From 200868456102c94feeea7d74ca5504a043f88926 Mon Sep 17 00:00:00 2001 From: Cornelius Roemer Date: Tue, 21 Nov 2023 18:07:55 +0100 Subject: [PATCH] Add v3 mpxv datasets, still some wip (#104) * Add v3 mpxv datasets, still some wip * fix: Update nextstrain collection with new mpox dataset paths * chore: rebuild [skip ci] * Update mpox datasets * chore: rebuild [skip ci] --------- Co-authored-by: nextstrain-bot --- data/nextstrain/collection.json | 6 +- data/nextstrain/mpox/all-clades/CHANGELOG.md | 13 + data/nextstrain/mpox/all-clades/README.md | 23 + .../mpox/all-clades/genome_annotation.gff3 | 391 + data/nextstrain/mpox/all-clades/pathogen.json | 212 + .../mpox/all-clades/reference.fasta | 2 + .../all-clades}/sequences.fasta | 0 data/nextstrain/mpox/all-clades/tree.json | 1 + data/nextstrain/mpox/clade-iib/CHANGELOG.md | 13 + data/nextstrain/mpox/clade-iib/README.md | 23 + .../mpox/clade-iib/genome_annotation.gff3 | 391 + data/nextstrain/mpox/clade-iib/pathogen.json | 92 + .../nextstrain/mpox/clade-iib/reference.fasta | 2 + .../clade-iib}/sequences.fasta | 0 data/nextstrain/mpox/clade-iib/tree.json | 1 + data/nextstrain/mpox/lineage-b.1/CHANGELOG.md | 13 + data/nextstrain/mpox/lineage-b.1/README.md | 24 + .../mpox/lineage-b.1/genome_annotation.gff3 | 391 + .../nextstrain/mpox/lineage-b.1/pathogen.json | 284 + .../mpox/lineage-b.1/reference.fasta | 2 + .../lineage-b.1}/sequences.fasta | 0 data/nextstrain/mpox/lineage-b.1/tree.json | 1 + .../mpx/hmpxv-b1/pseudo_ON563414/CHANGELOG.md | 7 - .../mpx/hmpxv-b1/pseudo_ON563414/README.md | 14 - .../pseudo_ON563414/genome_annotation.gff3 | 361 - .../hmpxv-b1/pseudo_ON563414/reference.fasta | 3288 - .../mpx/hmpxv-b1/pseudo_ON563414/tree.json | 91637 ---------- .../mpx/hmpxv/NC_063383.1/CHANGELOG.md | 7 - .../mpx/hmpxv/NC_063383.1/README.md | 14 - .../hmpxv/NC_063383.1/genome_annotation.gff3 | 361 - .../mpx/hmpxv/NC_063383.1/reference.fasta | 2820 - .../mpx/hmpxv/NC_063383.1/tree.json | 106766 ----------- .../mpx/mpxv/ancestral/CHANGELOG.md | 7 - data/nextstrain/mpx/mpxv/ancestral/README.md | 14 - .../mpx/mpxv/ancestral/genome_annotation.gff3 | 361 - .../mpx/mpxv/ancestral/reference.fasta | 3288 - data/nextstrain/mpx/mpxv/ancestral/tree.json | 142361 --------------- data_output/index.json | 104 +- data_output/minimizer_index.json | 1261 +- .../unreleased/CHANGELOG.md | 14 + .../unreleased/README.md | 27 + .../unreleased/genome_annotation.gff3 | 391 + .../unreleased}/pathogen.json | 43 +- .../unreleased/reference.fasta | 2 + .../unreleased/sequences.fasta | 18 + .../unreleased/tree.json | 1 + .../mpox/all-clades/unreleased/CHANGELOG.md | 13 + .../mpox/all-clades/unreleased/README.md | 23 + .../unreleased/genome_annotation.gff3 | 391 + .../mpox/all-clades/unreleased/pathogen.json | 212 + .../all-clades/unreleased/reference.fasta | 2 + .../all-clades/unreleased/sequences.fasta | 18 + .../mpox/all-clades/unreleased/tree.json | 1 + .../clade-iib/rivers/unreleased/CHANGELOG.md | 14 + .../clade-iib/rivers/unreleased/README.md | 27 + .../rivers/unreleased/genome_annotation.gff3 | 391 + .../rivers/unreleased}/pathogen.json | 43 +- .../rivers/unreleased/reference.fasta | 2 + .../rivers/unreleased/sequences.fasta | 10 + .../clade-iib/rivers/unreleased/tree.json | 1 + .../mpox/clade-iib/unreleased/CHANGELOG.md | 13 + .../mpox/clade-iib/unreleased/README.md | 23 + .../unreleased/genome_annotation.gff3 | 391 + .../mpox/clade-iib/unreleased/pathogen.json | 92 + .../mpox/clade-iib/unreleased/reference.fasta | 2 + .../mpox/clade-iib/unreleased/sequences.fasta | 10 + .../mpox/clade-iib/unreleased/tree.json | 1 + .../unreleased/CHANGELOG.md | 12 + .../unreleased/README.md | 27 + .../unreleased/genome_annotation.gff3 | 391 + .../unreleased}/pathogen.json | 43 +- .../unreleased/reference.fasta | 2 + .../unreleased/sequences.fasta | 18 + .../unreleased/tree.json | 1 + .../mpox/lineage-b.1/unreleased/CHANGELOG.md | 13 + .../mpox/lineage-b.1/unreleased/README.md | 24 + .../unreleased/genome_annotation.gff3 | 391 + .../mpox/lineage-b.1/unreleased/pathogen.json | 284 + .../lineage-b.1/unreleased/reference.fasta | 2 + .../lineage-b.1/unreleased/sequences.fasta | 18 + .../mpox/lineage-b.1/unreleased/tree.json | 1 + 81 files changed, 5661 insertions(+), 352298 deletions(-) create mode 100644 data/nextstrain/mpox/all-clades/CHANGELOG.md create mode 100644 data/nextstrain/mpox/all-clades/README.md create mode 100644 data/nextstrain/mpox/all-clades/genome_annotation.gff3 create mode 100644 data/nextstrain/mpox/all-clades/pathogen.json create mode 100644 data/nextstrain/mpox/all-clades/reference.fasta rename data/nextstrain/{mpx/mpxv/ancestral => mpox/all-clades}/sequences.fasta (100%) create mode 100644 data/nextstrain/mpox/all-clades/tree.json create mode 100644 data/nextstrain/mpox/clade-iib/CHANGELOG.md create mode 100644 data/nextstrain/mpox/clade-iib/README.md create mode 100644 data/nextstrain/mpox/clade-iib/genome_annotation.gff3 create mode 100644 data/nextstrain/mpox/clade-iib/pathogen.json create mode 100644 data/nextstrain/mpox/clade-iib/reference.fasta rename data/nextstrain/{mpx/hmpxv-b1/pseudo_ON563414 => mpox/clade-iib}/sequences.fasta (100%) create mode 100644 data/nextstrain/mpox/clade-iib/tree.json create mode 100644 data/nextstrain/mpox/lineage-b.1/CHANGELOG.md create mode 100644 data/nextstrain/mpox/lineage-b.1/README.md create mode 100644 data/nextstrain/mpox/lineage-b.1/genome_annotation.gff3 create mode 100644 data/nextstrain/mpox/lineage-b.1/pathogen.json create mode 100644 data/nextstrain/mpox/lineage-b.1/reference.fasta rename data/nextstrain/{mpx/hmpxv/NC_063383.1 => mpox/lineage-b.1}/sequences.fasta (100%) create mode 100644 data/nextstrain/mpox/lineage-b.1/tree.json delete mode 100644 data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/CHANGELOG.md delete mode 100644 data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/README.md delete mode 100644 data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/genome_annotation.gff3 delete mode 100644 data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/reference.fasta delete mode 100644 data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/tree.json delete mode 100644 data/nextstrain/mpx/hmpxv/NC_063383.1/CHANGELOG.md delete mode 100644 data/nextstrain/mpx/hmpxv/NC_063383.1/README.md delete mode 100644 data/nextstrain/mpx/hmpxv/NC_063383.1/genome_annotation.gff3 delete mode 100644 data/nextstrain/mpx/hmpxv/NC_063383.1/reference.fasta delete mode 100644 data/nextstrain/mpx/hmpxv/NC_063383.1/tree.json delete mode 100644 data/nextstrain/mpx/mpxv/ancestral/CHANGELOG.md delete mode 100644 data/nextstrain/mpx/mpxv/ancestral/README.md delete mode 100644 data/nextstrain/mpx/mpxv/ancestral/genome_annotation.gff3 delete mode 100644 data/nextstrain/mpx/mpxv/ancestral/reference.fasta delete mode 100644 data/nextstrain/mpx/mpxv/ancestral/tree.json create mode 100644 data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/CHANGELOG.md create mode 100644 data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/README.md create mode 100644 data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/genome_annotation.gff3 rename {data/nextstrain/mpx/mpxv/ancestral => data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased}/pathogen.json (83%) create mode 100644 data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/reference.fasta create mode 100644 data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/sequences.fasta create mode 100644 data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/tree.json create mode 100644 data_output/nextstrain/mpox/all-clades/unreleased/CHANGELOG.md create mode 100644 data_output/nextstrain/mpox/all-clades/unreleased/README.md create mode 100644 data_output/nextstrain/mpox/all-clades/unreleased/genome_annotation.gff3 create mode 100644 data_output/nextstrain/mpox/all-clades/unreleased/pathogen.json create mode 100644 data_output/nextstrain/mpox/all-clades/unreleased/reference.fasta create mode 100644 data_output/nextstrain/mpox/all-clades/unreleased/sequences.fasta create mode 100644 data_output/nextstrain/mpox/all-clades/unreleased/tree.json create mode 100644 data_output/nextstrain/mpox/clade-iib/rivers/unreleased/CHANGELOG.md create mode 100644 data_output/nextstrain/mpox/clade-iib/rivers/unreleased/README.md create mode 100644 data_output/nextstrain/mpox/clade-iib/rivers/unreleased/genome_annotation.gff3 rename {data/nextstrain/mpx/hmpxv/NC_063383.1 => data_output/nextstrain/mpox/clade-iib/rivers/unreleased}/pathogen.json (69%) create mode 100644 data_output/nextstrain/mpox/clade-iib/rivers/unreleased/reference.fasta create mode 100644 data_output/nextstrain/mpox/clade-iib/rivers/unreleased/sequences.fasta create mode 100644 data_output/nextstrain/mpox/clade-iib/rivers/unreleased/tree.json create mode 100644 data_output/nextstrain/mpox/clade-iib/unreleased/CHANGELOG.md create mode 100644 data_output/nextstrain/mpox/clade-iib/unreleased/README.md create mode 100644 data_output/nextstrain/mpox/clade-iib/unreleased/genome_annotation.gff3 create mode 100644 data_output/nextstrain/mpox/clade-iib/unreleased/pathogen.json create mode 100644 data_output/nextstrain/mpox/clade-iib/unreleased/reference.fasta create mode 100644 data_output/nextstrain/mpox/clade-iib/unreleased/sequences.fasta create mode 100644 data_output/nextstrain/mpox/clade-iib/unreleased/tree.json create mode 100644 data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/CHANGELOG.md create mode 100644 data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/README.md create mode 100644 data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/genome_annotation.gff3 rename {data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414 => data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased}/pathogen.json (84%) create mode 100644 data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/reference.fasta create mode 100644 data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/sequences.fasta create mode 100644 data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/tree.json create mode 100644 data_output/nextstrain/mpox/lineage-b.1/unreleased/CHANGELOG.md create mode 100644 data_output/nextstrain/mpox/lineage-b.1/unreleased/README.md create mode 100644 data_output/nextstrain/mpox/lineage-b.1/unreleased/genome_annotation.gff3 create mode 100644 data_output/nextstrain/mpox/lineage-b.1/unreleased/pathogen.json create mode 100644 data_output/nextstrain/mpox/lineage-b.1/unreleased/reference.fasta create mode 100644 data_output/nextstrain/mpox/lineage-b.1/unreleased/sequences.fasta create mode 100644 data_output/nextstrain/mpox/lineage-b.1/unreleased/tree.json diff --git a/data/nextstrain/collection.json b/data/nextstrain/collection.json index af57b161..7ff3af32 100644 --- a/data/nextstrain/collection.json +++ b/data/nextstrain/collection.json @@ -34,9 +34,9 @@ "nextstrain/flu/yam/ha/JN993010", "nextstrain/rsv/a/EPI_ISL_412866", "nextstrain/rsv/b/EPI_ISL_1653999", - "nextstrain/mpx/hmpxv-b1/pseudo_ON563414", - "nextstrain/mpx/hmpxv/NC_063383.1", - "nextstrain/mpx/mpxv/ancestral", + "nextstrain/mpox/all-clades", + "nextstrain/mpox/clade-iib", + "nextstrain/mpox/lineage-b.1", "nextstrain/ebola/zaire", "nextstrain/enterovirus/d68/fermon", "nextstrain/hiv/1", diff --git a/data/nextstrain/mpox/all-clades/CHANGELOG.md b/data/nextstrain/mpox/all-clades/CHANGELOG.md new file mode 100644 index 00000000..919c624d --- /dev/null +++ b/data/nextstrain/mpox/all-clades/CHANGELOG.md @@ -0,0 +1,13 @@ +## Unreleased + +Initial release of this dataset. This dataset is similar to the v2 dataset [`MPXV/ancestral`](https://github.com/nextstrain/nextclade_data/tree/2023-08-17--15-51-24--UTC/data/datasets/MPXV/references/ancestral/versions/2023-08-01T12%3A00%3A00Z/files) with some differences. + +### New and changed gene names + +Some genes have been renamed and one has been added. The new annotation is based on NCBI refseq annotations that were released in November 2022. The v2 dataset predates this refseq: + +- The 4 genes in the inverted terminal repeat segment (ITR) on both ends of the genome (OPG001, OPG002, OPG003,OPG015) are now all included. The genes on the 3' end (~positions 190000-197000) now have an `_dup` appended to distinguish them. +- The gene previously named `NBT03_gp052` is now called `OPG073` +- The gene previously named `NBT03_gp174` is now called `OPG016` +- The gene previously named `NBT03_gp175` is now called `OPG015_dup` +- Gene `OPG166` has been added diff --git a/data/nextstrain/mpox/all-clades/README.md b/data/nextstrain/mpox/all-clades/README.md new file mode 100644 index 00000000..8893afb1 --- /dev/null +++ b/data/nextstrain/mpox/all-clades/README.md @@ -0,0 +1,23 @@ +# Nextclade dataset for "Mpox virus (All Clades)" + +| Key | Value | +| ---------------------- | --------------------------------------------------------------------------------------------------------------------- | +| authors | [Cornelius Roemer](https://neherlab.org), [Richard Neher](https://neherlab.org), [Nextstrain](https://nextstrain.org) | +| data source | Genbank | +| workflow | [github.com/nextstrain/mpox/nextclade](https://github.com/nextstrain/mpox/nextclade) | +| nextclade dataset path | nextstrain/mpox/all-clades | +| annotation | [NC_063383.1](https://www.ncbi.nlm.nih.gov/nuccore/NC_063383) | +| clade definitions | [github.com/mpxv-lineages/lineage-designation](https://github.com/mpxv-lineages/lineage-designation) | +| related datasets | Mpox virus (Clade IIb): `nextstrain/mpox/clade-iib`
Mpox virus (Lineage B.1) `nextstrain/mpox/lineage-b.1` | + +This dataset is for Mpox viruses of all clades (I, IIa and IIb). For a focused analysis of sequences from clade IIb, you may want to use the more specific dataset: "Clade IIb" (`nextstrain/mpox/clade-iib`). For an even more focused analysis of 2022-2023 outbreak sequences (lineage B.1 and sublineages), you may want to use the even more specific dataset: "Lineage B.1" (`nextstrain/mpox/lineage-b.1`). + +The lineage system used is defined in [Happi et al. (2022)](https://doi.org/10.1371/journal.pbio.3001769). Lineage definitions are available at [github.com/mpxv-lineages/lineage-designation](https://github.com/nextstrain/mpox/nextclade). + +The reference used in this dataset is the clade IIb NCBI refseq `NC_063383.1` (Isolate `MPXV-M5312_HM12_Rivers`). + +The reference tree consists of around 500 sequences with representatives from all clades and lineages. + +## Further reading + +Read more about Nextclade datasets in Nextclade documentation: https://docs.nextstrain.org/projects/nextclade/en/stable/user/datasets.html diff --git a/data/nextstrain/mpox/all-clades/genome_annotation.gff3 b/data/nextstrain/mpox/all-clades/genome_annotation.gff3 new file mode 100644 index 00000000..432d5465 --- /dev/null +++ b/data/nextstrain/mpox/all-clades/genome_annotation.gff3 @@ -0,0 +1,391 @@ +##gff-version 3 +#!gff-spec-version 1.21 +#!processor NCBI annotwriter +##sequence-region NC_063383.1 1 197209 +##species https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10244 +NC_063383.1 RefSeq region 1 197209 . + . ID=NC_063383.1:1..197209;Dbxref=taxon:10244;collection-date=2018-08;country=Nigeria: Rivers State;gbkey=Src;genome=genomic;genotype=MPXV clade 2;isolate=MPXV-M5312_HM12_Rivers;mol_type=genomic DNA;nat-host=Homo sapiens +NC_063383.1 RefSeq long_terminal_repeat 1 6422 . - . ID=id-NC_063383.1:1..6422;gbkey=repeat_region;rpt_type=long_terminal_repeat +NC_063383.1 RefSeq gene 835 1575 . - . ID=gene-NBT03_gp001;Dbxref=GeneID:72551607;Name=OPG001;gbkey=Gene;gene=OPG001;gene_biotype=protein_coding;locus_tag=NBT03_gp001;old_locus_tag=MPXV-M5312_HM12_Rivers-001 +NC_063383.1 RefSeq CDS 835 1575 . - 0 ID=cds-YP_010377002.1;Parent=gene-NBT03_gp001;Dbxref=GenBank:YP_010377002.1,GeneID:72551607;Name=OPG001;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp001%3B Chemokine binding protein (Cop-C23L)%3B most abundant secreted protein%3B CC-chemokine binding%3B similar to VACV-WR J1L and VACV-Cop C23L;gbkey=CDS;gene=OPG001;locus_tag=NBT03_gp001;product=Chemokine binding protein;protein_id=YP_010377002.1 +NC_063383.1 RefSeq gene 1702 2751 . - . ID=gene-NBT03_gp002;Dbxref=GeneID:72551418;Name=OPG002;gbkey=Gene;gene=OPG002;gene_biotype=protein_coding;locus_tag=NBT03_gp002;old_locus_tag=MPXV-M5312_HM12_Rivers-002 +NC_063383.1 RefSeq CDS 1702 2751 . - 0 ID=cds-YP_010377003.1;Parent=gene-NBT03_gp002;Dbxref=GenBank:YP_010377003.1,GeneID:72551418;Name=OPG002;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: NBT03_gp002%3B TNF receptor (CrmB)%3B similar to VACV-WR J2L and VACV-Cop C22L;gbkey=CDS;gene=OPG002;locus_tag=NBT03_gp002;product=Crm-B secreted TNF-alpha-receptor-like protein;protein_id=YP_010377003.1 +NC_063383.1 RefSeq gene 2841 4607 . - . ID=gene-NBT03_gp003;Dbxref=GeneID:72551419;Name=OPG003;gbkey=Gene;gene=OPG003;gene_biotype=protein_coding;locus_tag=NBT03_gp003;old_locus_tag=MPXV-M5312_HM12_Rivers-003 +NC_063383.1 RefSeq CDS 2841 4607 . - 0 ID=cds-YP_010377004.1;Parent=gene-NBT03_gp003;Dbxref=GenBank:YP_010377004.1,GeneID:72551419;Name=OPG003;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp003%3B Ankyrin%3B similar to VACV-WR J3L and VACV-Cop C19L;gbkey=CDS;gene=OPG003;locus_tag=NBT03_gp003;product=Ankyrin repeat protein (25);protein_id=YP_010377004.1 +NC_063383.1 RefSeq gene 4843 6156 . - . ID=gene-NBT03_gp004;Dbxref=GeneID:72551420;Name=OPG015;gbkey=Gene;gene=OPG015;gene_biotype=protein_coding;locus_tag=NBT03_gp004;old_locus_tag=MPXV-M5312_HM12_Rivers-004 +NC_063383.1 RefSeq CDS 4843 6156 . - 0 ID=cds-YP_010377005.1;Parent=gene-NBT03_gp004;Dbxref=GenBank:YP_010377005.1,GeneID:72551420;Name=OPG015;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp004%3B Ankyrin%3B similar to VACV-WR D1L and CPXV-017;gbkey=CDS;gene=OPG015;locus_tag=NBT03_gp004;product=Ankyrin repeat protein (39);protein_id=YP_010377005.1 +NC_063383.1 RefSeq sequence_feature 6270 6419 . - . ID=id-NC_063383.1:6270..6419;exon_number=OPG016;gbkey=misc_feature;number=OPG016 +NC_063383.1 RefSeq sequence_feature 6444 6885 . - . ID=id-NC_063383.1:6444..6885;exon_number=OPG017;gbkey=misc_feature;number=OPG017 +NC_063383.1 RefSeq sequence_feature 6966 7463 . - . ID=id-NC_063383.1:6966..7463;exon_number=OPG018;gbkey=misc_feature;number=OPG018 +NC_063383.1 RefSeq gene 7580 8008 . + . ID=gene-NBT03_gp005;Dbxref=GeneID:72551421;Name=OPG019;gbkey=Gene;gene=OPG019;gene_biotype=protein_coding;locus_tag=NBT03_gp005;old_locus_tag=MPXV-M5312_HM12_Rivers-006 +NC_063383.1 RefSeq CDS 7580 8008 . + 0 ID=cds-YP_010377006.1;Parent=gene-NBT03_gp005;Dbxref=GenBank:YP_010377006.1,GeneID:72551421;Name=OPG019;Note=Taxonomic breadth: chordopoxvirinae%3B secreted growth factor Secreted EGF-like protein%3B similar to VACV-WR D3R and VACV-Cop C11R;gbkey=CDS;gene=OPG019;locus_tag=NBT03_gp005;product=EGF-like domain protein;protein_id=YP_010377006.1 +NC_063383.1 RefSeq sequence_feature 8136 9102 . - . ID=id-NC_063383.1:8136..9102;exon_number=OPG020;gbkey=misc_feature;number=OPG020 +NC_063383.1 RefSeq gene 9587 10315 . + . ID=gene-NBT03_gp006;Dbxref=GeneID:72551422;Name=OPG021;gbkey=Gene;gene=OPG021;gene_biotype=protein_coding;locus_tag=NBT03_gp006;old_locus_tag=MPXV-M5312_HM12_Rivers-008 +NC_063383.1 RefSeq CDS 9587 10315 . + 0 ID=cds-YP_010377007.1;Parent=gene-NBT03_gp006;Dbxref=GenBank:YP_010377007.1,GeneID:72551422;Name=OPG021;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp008%3B Zinc finger-like protein%3B zinc binding%3B virosome localization%3B virulence factor%3B inhibition of apoptosis induced by UV irradiation%3B similar to VACV-WR D5R;gbkey=CDS;gene=OPG021;locus_tag=NBT03_gp006;product=Zinc finger-like protein (2);protein_id=YP_010377007.1 +NC_063383.1 RefSeq gene 10478 10858 . - . ID=gene-NBT03_gp007;Dbxref=GeneID:72551423;Name=OPG022;gbkey=Gene;gene=OPG022;gene_biotype=protein_coding;locus_tag=NBT03_gp007;old_locus_tag=MPXV-M5312_HM12_Rivers-009 +NC_063383.1 RefSeq CDS 10478 10858 . - 0 ID=cds-YP_010377008.1;Parent=gene-NBT03_gp007;Dbxref=GenBank:YP_010377008.1,GeneID:72551423;Name=OPG022;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp009%3B secreted IL-18 binding protein%3B Soluble IL-18 binding protein (Bsh-D7L)%3B similar to VACV-WR D6L;gbkey=CDS;gene=OPG022;locus_tag=NBT03_gp007;product=Interleukin-18-binding protein;protein_id=YP_010377008.1 +NC_063383.1 RefSeq gene 10918 12900 . - . ID=gene-NBT03_gp008;Dbxref=GeneID:72551424;Name=OPG023;gbkey=Gene;gene=OPG023;gene_biotype=protein_coding;locus_tag=NBT03_gp008;old_locus_tag=MPXV-M5312_HM12_Rivers-010 +NC_063383.1 RefSeq CDS 10918 12900 . - 0 ID=cds-YP_010377009.1;Parent=gene-NBT03_gp008;Dbxref=GenBank:YP_010377009.1,GeneID:72551424;Name=OPG023;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp010%3B host range%3B ankyrin-like%3B Ankyrin/Host Range (Bang-D8L)%3B similar to VACV-WR D7L;gbkey=CDS;gene=OPG023;locus_tag=NBT03_gp008;product=Ankyrin repeat protein (2);protein_id=YP_010377009.1 +NC_063383.1 RefSeq gene 13034 13228 . - . ID=gene-NBT03_gp009;Dbxref=GeneID:72551425;Name=OPG024;gbkey=Gene;gene=OPG024;gene_biotype=protein_coding;locus_tag=NBT03_gp009;old_locus_tag=MPXV-M5312_HM12_Rivers-011 +NC_063383.1 RefSeq CDS 13034 13228 . - 0 ID=cds-YP_010377010.1;Parent=gene-NBT03_gp009;Dbxref=GenBank:YP_010377010.1,GeneID:72551425;Name=OPG024;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp011%3B ANK-containing protein%3B similar to VACV-WR D8L;gbkey=CDS;gene=OPG024;locus_tag=NBT03_gp009;product=retroviral pseudoprotease-like protein;protein_id=YP_010377010.1 +NC_063383.1 RefSeq gene 13375 15267 . - . ID=gene-NBT03_gp010;Dbxref=GeneID:72551426;Name=OPG025;gbkey=Gene;gene=OPG025;gene_biotype=protein_coding;locus_tag=NBT03_gp010;old_locus_tag=MPXV-M5312_HM12_Rivers-012 +NC_063383.1 RefSeq CDS 13375 15267 . - 0 ID=cds-YP_010377011.1;Parent=gene-NBT03_gp010;Dbxref=GenBank:YP_010377011.1,GeneID:72551426;Name=OPG025;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp012%3B ankyrin-like%3B Type I IFN resistance%3B similar to VACV-WR D9L and VACV-Cop C9L;gbkey=CDS;gene=OPG025;locus_tag=NBT03_gp010;product=Ankyrin repeat protein (14);protein_id=YP_010377011.1 +NC_063383.1 RefSeq sequence_feature 15310 15854 . - . ID=id-NC_063383.1:15310..15854;exon_number=OPG026;gbkey=misc_feature;number=OPG026 +NC_063383.1 RefSeq gene 15925 16377 . - . ID=gene-NBT03_gp011;Dbxref=GeneID:72551427;Name=OPG027;gbkey=Gene;gene=OPG027;gene_biotype=protein_coding;locus_tag=NBT03_gp011;old_locus_tag=MPXV-M5312_HM12_Rivers-013 +NC_063383.1 RefSeq CDS 15925 16377 . - 0 ID=cds-YP_010377012.1;Parent=gene-NBT03_gp011;Dbxref=GenBank:YP_010377012.1,GeneID:72551427;Name=OPG027;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp013%3B host range%3B Type 1 IFN inhibitor%3B similar to VACV-WR D10L and VACV-Cop C7L;gbkey=CDS;gene=OPG027;locus_tag=NBT03_gp011;product=Host range protein;protein_id=YP_010377012.1 +NC_063383.1 RefSeq gene 16602 17069 . - . ID=gene-NBT03_gp012;Dbxref=GeneID:72551428;Name=OPG029;gbkey=Gene;gene=OPG029;gene_biotype=protein_coding;locus_tag=NBT03_gp012;old_locus_tag=MPXV-M5312_HM12_Rivers-014 +NC_063383.1 RefSeq CDS 16602 17069 . - 0 ID=cds-YP_010377013.1;Parent=gene-NBT03_gp012;Dbxref=GenBank:YP_010377013.1,GeneID:72551428;Name=OPG029;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp014%3B Putative tlr signaling inhibitor%2C IFN-beta inhibitor%3B similar to VACV-WR D11L and VACV-Cop C6L;gbkey=CDS;gene=OPG029;locus_tag=NBT03_gp012;product=Bcl-2-like protein;protein_id=YP_010377013.1 +NC_063383.1 RefSeq gene 17213 17833 . - . ID=gene-NBT03_gp013;Dbxref=GeneID:72551429;Name=OPG030;gbkey=Gene;gene=OPG030;gene_biotype=protein_coding;locus_tag=NBT03_gp013;old_locus_tag=MPXV-M5312_HM12_Rivers-015 +NC_063383.1 RefSeq CDS 17213 17833 . - 0 ID=cds-YP_010377014.1;Parent=gene-NBT03_gp013;Dbxref=GenBank:YP_010377014.1,GeneID:72551429;Name=OPG030;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp015%3B BTB domain of kelch-like protein%3B Kelch-like protein%3B similar to VACV-WR D12L and VACV-Cop C5L;gbkey=CDS;gene=OPG030;locus_tag=NBT03_gp013;product=Kelch-like protein (1);protein_id=YP_010377014.1 +NC_063383.1 RefSeq gene 17878 18828 . - . ID=gene-NBT03_gp014;Dbxref=GeneID:72551430;Name=OPG031;gbkey=Gene;gene=OPG031;gene_biotype=protein_coding;locus_tag=NBT03_gp014;old_locus_tag=MPXV-M5312_HM12_Rivers-016 +NC_063383.1 RefSeq CDS 17878 18828 . - 0 ID=cds-YP_010377015.1;Parent=gene-NBT03_gp014;Dbxref=GenBank:YP_010377015.1,GeneID:72551430;Name=OPG031;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp016%3B IL-1 receptor antagonist%3B similar to VACV-WR D13L and VACV-Cop C10L;gbkey=CDS;gene=OPG031;locus_tag=NBT03_gp014;product=C4L/C10L-like family protein;protein_id=YP_010377015.1 +NC_063383.1 RefSeq sequence_feature 18902 19288 . - . ID=id-NC_063383.1:18902..19288;exon_number=OPG033;gbkey=misc_feature;number=OPG033 +NC_063383.1 RefSeq gene 19361 20005 . - . ID=gene-NBT03_gp015;Dbxref=GeneID:72551431;Name=OPG034;gbkey=Gene;gene=OPG034;gene_biotype=protein_coding;locus_tag=NBT03_gp015;old_locus_tag=MPXV-M5312_HM12_Rivers-018 +NC_063383.1 RefSeq CDS 19361 20005 . - 0 ID=cds-YP_010377017.1;Parent=gene-NBT03_gp015;Dbxref=GenBank:YP_010377017.1,GeneID:72551431;Name=OPG034;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp022%3B Putative TLR signalling inhibitor%3B start of ORF is missing approx. 18 AA compared to CPXVs%3B similar to VACV-WR D19L and VACV-Cop C1L;gbkey=CDS;gene=OPG034;locus_tag=NBT03_gp015;product=Bcl-2-like protein;protein_id=YP_010377017.1 +NC_063383.1 RefSeq gene 20051 20404 . - . ID=gene-NBT03_gp016;Dbxref=GeneID:72551432;Name=OPG035;gbkey=Gene;gene=OPG035;gene_biotype=protein_coding;locus_tag=NBT03_gp016;old_locus_tag=MPXV-M5312_HM12_Rivers-019 +NC_063383.1 RefSeq CDS 20051 20404 . - 0 ID=cds-YP_010377018.1;Parent=gene-NBT03_gp016;Dbxref=GenBank:YP_010377018.1,GeneID:72551432;Name=OPG035;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp023%3B secreted virulence factor%3B Putative tlr signaling inhibitor%3B Anti-apoptotic Bcl-2-like protein%3B similar to VACV-WR P1L and VACV-Cop N1L;gbkey=CDS;gene=OPG035;locus_tag=NBT03_gp016;product=Bcl-2-like protein;protein_id=YP_010377018.1 +NC_063383.1 RefSeq gene 20531 21064 . - . ID=gene-NBT03_gp017;Dbxref=GeneID:72551433;Name=OPG036;gbkey=Gene;gene=OPG036;gene_biotype=protein_coding;locus_tag=NBT03_gp017;old_locus_tag=MPXV-M5312_HM12_Rivers-020 +NC_063383.1 RefSeq CDS 20531 21064 . - 0 ID=cds-YP_010377019.1;Parent=gene-NBT03_gp017;Dbxref=GenBank:YP_010377019.1,GeneID:72551433;Name=OPG036;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp024%3B Alpha amanatin target protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR P2L and VACV-Cop #N2L;gbkey=CDS;gene=OPG036;locus_tag=NBT03_gp017;product=Bcl-2-like protein;protein_id=YP_010377019.1 +NC_063383.1 RefSeq gene 21105 22433 . - . ID=gene-NBT03_gp018;Dbxref=GeneID:72551434;Name=OPG037;gbkey=Gene;gene=OPG037;gene_biotype=protein_coding;locus_tag=NBT03_gp018;old_locus_tag=MPXV-M5312_HM12_Rivers-021 +NC_063383.1 RefSeq CDS 21105 22433 . - 0 ID=cds-YP_010377020.1;Parent=gene-NBT03_gp018;Dbxref=GenBank:YP_010377020.1,GeneID:72551434;Name=OPG037;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp025%3B ankyrin-like%3B ANK-containing protein%3B apoptosis inhibitor%3B start of ORF is missing approx. 31 AA compared to CPXVs%3B similar to VACV-WR O1L and VACV-Cop M1L;gbkey=CDS;gene=OPG037;locus_tag=NBT03_gp018;product=Ankyrin-like protein (1);protein_id=YP_010377020.1 +NC_063383.1 RefSeq gene 22497 23159 . - . ID=gene-NBT03_gp019;Dbxref=GeneID:72551435;Name=OPG038;gbkey=Gene;gene=OPG038;gene_biotype=protein_coding;locus_tag=NBT03_gp019;old_locus_tag=MPXV-M5312_HM12_Rivers-022 +NC_063383.1 RefSeq CDS 22497 23159 . - 0 ID=cds-YP_010377021.1;Parent=gene-NBT03_gp019;Dbxref=GenBank:YP_010377021.1,GeneID:72551435;Name=OPG038;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp026%3B NFkB inhibitor%3B similar to VACV-WR O2L and VACV-Cop M2L;gbkey=CDS;gene=OPG038;locus_tag=NBT03_gp019;product=NFkB inhibitor;protein_id=YP_010377021.1 +NC_063383.1 RefSeq gene 23264 24118 . - . ID=gene-NBT03_gp020;Dbxref=GeneID:72551436;Name=OPG039;gbkey=Gene;gene=OPG039;gene_biotype=protein_coding;locus_tag=NBT03_gp020;old_locus_tag=MPXV-M5312_HM12_Rivers-023 +NC_063383.1 RefSeq CDS 23264 24118 . - 0 ID=cds-YP_010377022.1;Parent=gene-NBT03_gp020;Dbxref=GenBank:YP_010377022.1,GeneID:72551436;Name=OPG039;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp027%3B host range%3B ankyrin-like%3B Ankyrin/NFkB inhibitor%3B similar to VACV-WR C1L and VACV-Cop K1L;gbkey=CDS;gene=OPG039;locus_tag=NBT03_gp020;product=Ankyrin-like protein (3);protein_id=YP_010377022.1 +NC_063383.1 RefSeq gene 24351 25478 . - . ID=gene-NBT03_gp021;Dbxref=GeneID:72551437;Name=OPG040;gbkey=Gene;gene=OPG040;gene_biotype=protein_coding;locus_tag=NBT03_gp021;old_locus_tag=MPXV-M5312_HM12_Rivers-024 +NC_063383.1 RefSeq CDS 24351 25478 . - 0 ID=cds-YP_010377023.1;Parent=gene-NBT03_gp021;Dbxref=GenBank:YP_010377023.1,GeneID:72551437;Name=OPG040;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp028%3B serine protease inhibitor-like%2C SPI-3%3B inhibition of the ability of infected cells to fuse%3B Serpin 1%2C2%2C3%3B similar to VACV-WR C2L and VACV-Cop K2L;gbkey=CDS;gene=OPG040;locus_tag=NBT03_gp021;product=Serpin;protein_id=YP_010377023.1 +NC_063383.1 RefSeq sequence_feature 25529 25767 . - . ID=id-NC_063383.1:25529..25767;exon_number=OPG041;gbkey=misc_feature;number=OPG041 +NC_063383.1 RefSeq gene 25823 27097 . - . ID=gene-NBT03_gp022;Dbxref=GeneID:72551438;Name=OPG042;gbkey=Gene;gene=OPG042;gene_biotype=protein_coding;locus_tag=NBT03_gp022;old_locus_tag=MPXV-M5312_HM12_Rivers-026 +NC_063383.1 RefSeq CDS 25823 27097 . - 0 ID=cds-YP_010377025.1;Parent=gene-NBT03_gp022;Dbxref=GenBank:YP_010377025.1,GeneID:72551438;Name=OPG042;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp030%3B phospholipase D-like%3B Phospholipase-D-like protein%3B similar to VACV-WR C4L and VACV-Cop K4L;gbkey=CDS;gene=OPG042;locus_tag=NBT03_gp022;product=Phospholipase-D-like protein;protein_id=YP_010377025.1 +NC_063383.1 RefSeq gene 27125 27955 . - . ID=gene-NBT03_gp023;Dbxref=GeneID:72551439;Name=OPG043;gbkey=Gene;gene=OPG043;gene_biotype=protein_coding;locus_tag=NBT03_gp023;old_locus_tag=MPXV-M5312_HM12_Rivers-027 +NC_063383.1 RefSeq CDS 27125 27955 . - 0 ID=cds-YP_010377026.1;Parent=gene-NBT03_gp023;Dbxref=GenBank:YP_010377026.1,GeneID:72551439;Name=OPG043;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp031%3B lysophospholipase-like%3B Monoglyceride lipase%3B similar to VACV-WR C5L and VACV-Cop K5L;gbkey=CDS;gene=OPG043;locus_tag=NBT03_gp023;product=Putative monoglyceride lipase;protein_id=YP_010377026.1 +NC_063383.1 RefSeq gene 28091 28540 . + . ID=gene-NBT03_gp024;Dbxref=GeneID:72551440;Name=OPG044;gbkey=Gene;gene=OPG044;gene_biotype=protein_coding;locus_tag=NBT03_gp024;old_locus_tag=MPXV-M5312_HM12_Rivers-028 +NC_063383.1 RefSeq CDS 28091 28540 . + 0 ID=cds-YP_010377027.1;Parent=gene-NBT03_gp024;Dbxref=GenBank:YP_010377027.1,GeneID:72551440;Name=OPG044;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp032%3B Putative tlr signaling inhibitor%3B Host immune response repressor%3B similar to VACV-WR C6R and VACV-Cop #K7R;gbkey=CDS;gene=OPG044;locus_tag=NBT03_gp024;product=Bcl-2-like protein;protein_id=YP_010377027.1 +NC_063383.1 RefSeq gene 28603 29262 . - . ID=gene-NBT03_gp025;Dbxref=GeneID:72551441;Name=OPG045;gbkey=Gene;gene=OPG045;gene_biotype=protein_coding;locus_tag=NBT03_gp025;old_locus_tag=MPXV-M5312_HM12_Rivers-029 +NC_063383.1 RefSeq CDS 28603 29262 . - 0 ID=cds-YP_010377028.1;Parent=gene-NBT03_gp025;Dbxref=GenBank:YP_010377028.1,GeneID:72551441;Name=OPG045;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp033%3B Caspase-9 (apoptosis) inhibitor (mitochondrial- associated)%3B similar to VACV-WR C7L and VACV-Cop F1L;gbkey=CDS;gene=OPG045;locus_tag=NBT03_gp025;product=Caspase-9 inhibitor;protein_id=YP_010377028.1 +NC_063383.1 RefSeq gene 29274 29729 . - . ID=gene-NBT03_gp026;Dbxref=GeneID:72551442;Name=OPG046;gbkey=Gene;gene=OPG046;gene_biotype=protein_coding;locus_tag=NBT03_gp026;old_locus_tag=MPXV-M5312_HM12_Rivers-030 +NC_063383.1 RefSeq CDS 29274 29729 . - 0 ID=cds-YP_010377029.1;Parent=gene-NBT03_gp026;Dbxref=GenBank:YP_010377029.1,GeneID:72551442;Name=OPG046;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp034%3B deoxyuridine triphosphatase%3B dUTPase%3B similar to VACV-WR C8L and VACV-Cop F2L;gbkey=CDS;gene=OPG046;locus_tag=NBT03_gp026;product=dUTPase;protein_id=YP_010377029.1 +NC_063383.1 RefSeq gene 29746 31194 . - . ID=gene-NBT03_gp027;Dbxref=GeneID:72551443;Name=OPG047;gbkey=Gene;gene=OPG047;gene_biotype=protein_coding;locus_tag=NBT03_gp027;old_locus_tag=MPXV-M5312_HM12_Rivers-031 +NC_063383.1 RefSeq CDS 29746 31194 . - 0 ID=cds-YP_010377030.1;Parent=gene-NBT03_gp027;Dbxref=GenBank:YP_010377030.1,GeneID:72551443;Name=OPG047;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp035%3B kelch-like%3B Kelch-like protein%3B similar to VACV-WR C9L and VACV-Cop F3L;gbkey=CDS;gene=OPG047;locus_tag=NBT03_gp027;product=Kelch-like protein (2);protein_id=YP_010377030.1 +NC_063383.1 RefSeq gene 31205 32164 . - . ID=gene-NBT03_gp028;Dbxref=GeneID:72551444;Name=OPG048;gbkey=Gene;gene=OPG048;gene_biotype=protein_coding;locus_tag=NBT03_gp028;old_locus_tag=MPXV-M5312_HM12_Rivers-032 +NC_063383.1 RefSeq CDS 31205 32164 . - 0 ID=cds-YP_010377031.1;Parent=gene-NBT03_gp028;Dbxref=GenBank:YP_010377031.1,GeneID:72551444;Name=OPG048;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp036%3B Ribonucleotide reductase small subunit%2C R2%3B similar to VACV-WR C10L and VACV-Cop F4L;gbkey=CDS;gene=OPG048;locus_tag=NBT03_gp028;product=Ribonucleotide reductase small subunit;protein_id=YP_010377031.1 +NC_063383.1 RefSeq gene 32195 33151 . - . ID=gene-NBT03_gp029;Dbxref=GeneID:72551445;Name=OPG049;gbkey=Gene;gene=OPG049;gene_biotype=protein_coding;locus_tag=NBT03_gp029;old_locus_tag=MPXV-M5312_HM12_Rivers-033 +NC_063383.1 RefSeq CDS 32195 33151 . - 0 ID=cds-YP_010377032.1;Parent=gene-NBT03_gp029;Dbxref=GenBank:YP_010377032.1,GeneID:72551445;Name=OPG049;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp037%3B 36kDa major membrane protein%3B similar to VACV-WR C11L and VACV-Cop F5L;gbkey=CDS;gene=OPG049;locus_tag=NBT03_gp029;product=Telomere-binding protein I6 (1);protein_id=YP_010377032.1 +NC_063383.1 RefSeq gene 33181 33408 . - . ID=gene-NBT03_gp030;Dbxref=GeneID:72551446;Name=OPG050;gbkey=Gene;gene=OPG050;gene_biotype=protein_coding;locus_tag=NBT03_gp030;old_locus_tag=MPXV-M5312_HM12_Rivers-034 +NC_063383.1 RefSeq CDS 33181 33408 . - 0 ID=cds-YP_010377033.1;Parent=gene-NBT03_gp030;Dbxref=GenBank:YP_010377033.1,GeneID:72551446;Name=OPG050;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp038%3B Hypothetical protein%3B similar to VACV-WR C12L and VACV-Cop F6L;gbkey=CDS;gene=OPG050;locus_tag=NBT03_gp030;product=CPXV053 protein;protein_id=YP_010377033.1 +NC_063383.1 RefSeq gene 33425 33649 . - . ID=gene-NBT03_gp031;Dbxref=GeneID:72551447;Name=OPG051;gbkey=Gene;gene=OPG051;gene_biotype=protein_coding;locus_tag=NBT03_gp031;old_locus_tag=MPXV-M5312_HM12_Rivers-035 +NC_063383.1 RefSeq CDS 33425 33649 . - 0 ID=cds-YP_010377034.1;Parent=gene-NBT03_gp031;Dbxref=GenBank:YP_010377034.1,GeneID:72551447;Name=OPG051;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp039%3B Hypothetical protein%3B similar to VACV-WR C13L and VACV-Cop F7L;gbkey=CDS;gene=OPG051;locus_tag=NBT03_gp031;product=CPXV054 protein;protein_id=YP_010377034.1 +NC_063383.1 RefSeq gene 33801 33995 . - . ID=gene-NBT03_gp032;Dbxref=GeneID:72551448;Name=OPG052;gbkey=Gene;gene=OPG052;gene_biotype=protein_coding;locus_tag=NBT03_gp032;old_locus_tag=MPXV-M5312_HM12_Rivers-036 +NC_063383.1 RefSeq CDS 33801 33995 . - 0 ID=cds-YP_010377035.1;Parent=gene-NBT03_gp032;Dbxref=GenBank:YP_010377035.1,GeneID:72551448;Name=OPG052;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp040%3B Cytoplasmic protein%3B similar to VACV-WR C14L and VACV-Cop F8L;gbkey=CDS;gene=OPG052;locus_tag=NBT03_gp032;product=Cytoplasmic protein;protein_id=YP_010377035.1 +NC_063383.1 RefSeq gene 34052 34690 . - . ID=gene-NBT03_gp033;Dbxref=GeneID:72551449;Name=OPG053;gbkey=Gene;gene=OPG053;gene_biotype=protein_coding;locus_tag=NBT03_gp033;old_locus_tag=MPXV-M5312_HM12_Rivers-037 +NC_063383.1 RefSeq CDS 34052 34690 . - 0 ID=cds-YP_010377036.1;Parent=gene-NBT03_gp033;Dbxref=GenBank:YP_010377036.1,GeneID:72551449;Name=OPG053;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp041%3B S-S bond formation pathway protein substrate%3B similar to VACV-WR C15L and VACV-Cop F9L;gbkey=CDS;gene=OPG053;locus_tag=NBT03_gp033;product=IMV membrane protein L1R;protein_id=YP_010377036.1 +NC_063383.1 RefSeq gene 34677 35996 . - . ID=gene-NBT03_gp034;Dbxref=GeneID:72551450;Name=OPG054;gbkey=Gene;gene=OPG054;gene_biotype=protein_coding;locus_tag=NBT03_gp034;old_locus_tag=MPXV-M5312_HM12_Rivers-038 +NC_063383.1 RefSeq CDS 34677 35996 . - 0 ID=cds-YP_010377037.1;Parent=gene-NBT03_gp034;Dbxref=GenBank:YP_010377037.1,GeneID:72551450;Name=OPG054;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp042%3B serine%3B Essential Ser/Thr kinase morph%3B similar to VACV-WR C16L and VACV-Cop F10L;gbkey=CDS;gene=OPG054;locus_tag=NBT03_gp034;product=Serine/threonine-protein kinase;protein_id=YP_010377037.1 +NC_063383.1 RefSeq gene 36019 37083 . - . ID=gene-NBT03_gp035;Dbxref=GeneID:72551451;Name=OPG055;gbkey=Gene;gene=OPG055;gene_biotype=protein_coding;locus_tag=NBT03_gp035;old_locus_tag=MPXV-M5312_HM12_Rivers-039 +NC_063383.1 RefSeq CDS 36019 37083 . - 0 ID=cds-YP_010377038.1;Parent=gene-NBT03_gp035;Dbxref=GenBank:YP_010377038.1,GeneID:72551451;Name=OPG055;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp043%3B RhoA signalling inhibitor%2C virus release protein%3B MC018%3B similar to VACV-WR C17L and VACV-Cop F11L;gbkey=CDS;gene=OPG055;locus_tag=NBT03_gp035;product=Protein F11;protein_id=YP_010377038.1 +NC_063383.1 RefSeq gene 37127 39034 . - . ID=gene-NBT03_gp036;Dbxref=GeneID:72551452;Name=OPG056;gbkey=Gene;gene=OPG056;gene_biotype=protein_coding;locus_tag=NBT03_gp036;old_locus_tag=MPXV-M5312_HM12_Rivers-040 +NC_063383.1 RefSeq CDS 37127 39034 . - 0 ID=cds-YP_010377039.1;Parent=gene-NBT03_gp036;Dbxref=GenBank:YP_010377039.1,GeneID:72551452;Name=OPG056;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp044%3B actin tail formation%3B EEV maturation protein%3B similar to VACV-WR C18L and VACV-Cop F12L;gbkey=CDS;gene=OPG056;locus_tag=NBT03_gp036;product=EEV maturation protein;protein_id=YP_010377039.1 +NC_063383.1 RefSeq gene 39077 40195 . - . ID=gene-NBT03_gp037;Dbxref=GeneID:72551453;Name=OPG057;gbkey=Gene;gene=OPG057;gene_biotype=protein_coding;locus_tag=NBT03_gp037;old_locus_tag=MPXV-M5312_HM12_Rivers-041 +NC_063383.1 RefSeq CDS 39077 40195 . - 0 ID=cds-YP_010377040.1;Parent=gene-NBT03_gp037;Dbxref=GenBank:YP_010377040.1,GeneID:72551453;Name=OPG057;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp045%3B major envelope antigen of EEV%3B wrapping of IMV to form IEV%3B phospholipase D-like%3B Palmitylated EEV membrane glycoprotein%3B similar to VACV-WR C19L and VACV-Cop F13L;gbkey=CDS;gene=OPG057;locus_tag=NBT03_gp037;product=Palmytilated EEV membrane protein;protein_id=YP_010377040.1 +NC_063383.1 RefSeq gene 40213 40434 . - . ID=gene-NBT03_gp038;Dbxref=GeneID:72551454;Name=OPG058;gbkey=Gene;gene=OPG058;gene_biotype=protein_coding;locus_tag=NBT03_gp038;old_locus_tag=MPXV-M5312_HM12_Rivers-042 +NC_063383.1 RefSeq CDS 40213 40434 . - 0 ID=cds-YP_010377041.1;Parent=gene-NBT03_gp038;Dbxref=GenBank:YP_010377041.1,GeneID:72551454;Name=OPG058;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp046%3B similar to VACV-WR C20L and VACV-Cop F14L;gbkey=CDS;gene=OPG058;locus_tag=NBT03_gp038;product=Protein F14 (1);protein_id=YP_010377041.1 +NC_063383.1 RefSeq gene 40484 40633 . - . ID=gene-NBT03_gp039;Dbxref=GeneID:72551455;Name=OPG059;gbkey=Gene;gene=OPG059;gene_biotype=protein_coding;locus_tag=NBT03_gp039;old_locus_tag=MPXV-M5312_HM12_Rivers-043 +NC_063383.1 RefSeq CDS 40484 40633 . - 0 ID=cds-YP_010377042.1;Parent=gene-NBT03_gp039;Dbxref=GenBank:YP_010377042.1,GeneID:72551455;Name=OPG059;Note=Taxonomic breadth: poxvirinae%3B IMV protein%3B C20.5L%3B similar to VACV-CopF14.5L;gbkey=CDS;gene=OPG059;locus_tag=NBT03_gp039;product=Cytochrome C oxidase;protein_id=YP_010377042.1 +NC_063383.1 RefSeq gene 40706 41182 . - . ID=gene-NBT03_gp040;Dbxref=GeneID:72551456;Name=OPG060;gbkey=Gene;gene=OPG060;gene_biotype=protein_coding;locus_tag=NBT03_gp040;old_locus_tag=MPXV-M5312_HM12_Rivers-044 +NC_063383.1 RefSeq CDS 40706 41182 . - 0 ID=cds-YP_010377043.1;Parent=gene-NBT03_gp040;Dbxref=GenBank:YP_010377043.1,GeneID:72551456;Name=OPG060;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp047%3B Unknown conserved protein%3B similar to VACV-WR C21L and VACV-Cop F15L;gbkey=CDS;gene=OPG060;locus_tag=NBT03_gp040;product=Protein F15;protein_id=YP_010377043.1 +NC_063383.1 RefSeq gene 41189 41884 . - . ID=gene-NBT03_gp041;Dbxref=GeneID:72551457;Name=OPG061;gbkey=Gene;gene=OPG061;gene_biotype=protein_coding;locus_tag=NBT03_gp041;old_locus_tag=MPXV-M5312_HM12_Rivers-045 +NC_063383.1 RefSeq CDS 41189 41884 . - 0 ID=cds-YP_010377044.1;Parent=gene-NBT03_gp041;Dbxref=GenBank:YP_010377044.1,GeneID:72551457;Name=OPG061;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp048%3B Non-functional Serine Recombinase%3B similar to VACV-WR C22L and VACV-Cop F16L;gbkey=CDS;gene=OPG061;locus_tag=NBT03_gp041;product=Protein F16 (1);protein_id=YP_010377044.1 +NC_063383.1 RefSeq gene 41947 42252 . + . ID=gene-NBT03_gp042;Dbxref=GeneID:72551458;Name=OPG062;gbkey=Gene;gene=OPG062;gene_biotype=protein_coding;locus_tag=NBT03_gp042;old_locus_tag=MPXV-M5312_HM12_Rivers-046 +NC_063383.1 RefSeq CDS 41947 42252 . + 0 ID=cds-YP_010377045.1;Parent=gene-NBT03_gp042;Dbxref=GenBank:YP_010377045.1,GeneID:72551458;Name=OPG062;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp049%3B virion core DNA-binding phosphoprotein (VP11)%3B mTOR antagonist%3B similar to VACV-WR C23R and VACV-Cop F17R;gbkey=CDS;gene=OPG062;locus_tag=NBT03_gp042;product=DNA-binding phosphoprotein (1);protein_id=YP_010377045.1 +NC_063383.1 RefSeq gene 42249 43688 . - . ID=gene-NBT03_gp043;Dbxref=GeneID:72551459;Name=OPG063;gbkey=Gene;gene=OPG063;gene_biotype=protein_coding;locus_tag=NBT03_gp043;old_locus_tag=MPXV-M5312_HM12_Rivers-047 +NC_063383.1 RefSeq CDS 42249 43688 . - 0 ID=cds-YP_010377046.1;Parent=gene-NBT03_gp043;Dbxref=GenBank:YP_010377046.1,GeneID:72551459;Name=OPG063;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp050%3B poly-A polymerase%2C Poly (A) polymerase catalytic subunit (VP55)%3B similar to VACV-WR F1L and VACV-Cop E1L;gbkey=CDS;gene=OPG063;locus_tag=NBT03_gp043;product=Poly(A) polymerase catalytic subunit (3);protein_id=YP_010377046.1 +NC_063383.1 RefSeq gene 43685 45898 . - . ID=gene-NBT03_gp044;Dbxref=GeneID:72551460;Name=OPG064;gbkey=Gene;gene=OPG064;gene_biotype=protein_coding;locus_tag=NBT03_gp044;old_locus_tag=MPXV-M5312_HM12_Rivers-048 +NC_063383.1 RefSeq CDS 43685 45898 . - 0 ID=cds-YP_010377047.1;Parent=gene-NBT03_gp044;Dbxref=GenBank:YP_010377047.1,GeneID:72551460;Name=OPG064;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp051%3B IEV morphogenesis%3B similar to VACV-WR F2L and VACV-Cop E2L;gbkey=CDS;gene=OPG064;locus_tag=NBT03_gp044;product=Iev morphogenesis protein;protein_id=YP_010377047.1 +NC_063383.1 RefSeq gene 46022 46483 . - . ID=gene-NBT03_gp045;Dbxref=GeneID:72551461;Name=OPG065;gbkey=Gene;gene=OPG065;gene_biotype=protein_coding;locus_tag=NBT03_gp045;old_locus_tag=MPXV-M5312_HM12_Rivers-049 +NC_063383.1 RefSeq CDS 46022 46483 . - 0 ID=cds-YP_010377048.1;Parent=gene-NBT03_gp045;Dbxref=GenBank:YP_010377048.1,GeneID:72551461;Name=OPG065;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp052%3B interferon resistance factor%3B two forms (25 kDa and 19 kDa) of the dsRNA-binding protein%3B inhibition of dsRNA-dependent protein kinase and 2-5A-synthet%3B dsRNA-binding protein%2C IFN resistance/PKR inhibitor (Z-DNA binding)%3B start of ORF is missing approx. 37 AA compared to CPXVs%3B similar to VACV-WR F3L and VACV-Cop E3L;gbkey=CDS;gene=OPG065;locus_tag=NBT03_gp045;product=Double-stranded RNA binding protein;protein_id=YP_010377048.1 +NC_063383.1 RefSeq gene 46649 47428 . - . ID=gene-NBT03_gp046;Dbxref=GeneID:72551462;Name=OPG066;gbkey=Gene;gene=OPG066;gene_biotype=protein_coding;locus_tag=NBT03_gp046;old_locus_tag=MPXV-M5312_HM12_Rivers-050 +NC_063383.1 RefSeq CDS 46649 47428 . - 0 ID=cds-YP_010377049.1;Parent=gene-NBT03_gp046;Dbxref=GenBank:YP_010377049.1,GeneID:72551462;Name=OPG066;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp053%3B RNA polymerase 30 kDa subunit (RPO30)%3B simultaneously intermediate stage promoter-specific transcription factor%2C VITF-1%3B similar to VACV-WR F4L and VACV-Cop E4L;gbkey=CDS;gene=OPG066;locus_tag=NBT03_gp046;product=DNA-directed RNA polymerase 30 kDa polypeptide;protein_id=YP_010377049.1 +NC_063383.1 RefSeq sequence_feature 47525 48062 . + . ID=id-NC_063383.1:47525..48062;exon_number=OPG067;gbkey=misc_feature;number=OPG067 +NC_063383.1 RefSeq gene 48201 49904 . + . ID=gene-NBT03_gp047;Dbxref=GeneID:72551463;Name=OPG068;gbkey=Gene;gene=OPG068;gene_biotype=protein_coding;locus_tag=NBT03_gp047;old_locus_tag=MPXV-M5312_HM12_Rivers-052 +NC_063383.1 RefSeq CDS 48201 49904 . + 0 ID=cds-YP_010377051.1;Parent=gene-NBT03_gp047;Dbxref=GenBank:YP_010377051.1,GeneID:72551463;Name=OPG068;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp054%3B Virion protein%3B similar to VACV-WR F5R and VACV-Cop E6R;gbkey=CDS;gene=OPG068;locus_tag=NBT03_gp047;product=IMV membrane protein E6;protein_id=YP_010377051.1 +NC_063383.1 RefSeq gene 49986 50486 . + . ID=gene-NBT03_gp048;Dbxref=GeneID:72551464;Name=OPG069;gbkey=Gene;gene=OPG069;gene_biotype=protein_coding;locus_tag=NBT03_gp048;old_locus_tag=MPXV-M5312_HM12_Rivers-053 +NC_063383.1 RefSeq CDS 49986 50486 . + 0 ID=cds-YP_010377052.1;Parent=gene-NBT03_gp048;Dbxref=GenBank:YP_010377052.1,GeneID:72551464;Name=OPG069;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp055%3B soluble myristylated protein%3B similar to VACV-WR F6R and VACV-Cop E7R;gbkey=CDS;gene=OPG069;locus_tag=NBT03_gp048;product=Myristoylated protein E7;protein_id=YP_010377052.1 +NC_063383.1 RefSeq gene 50590 51411 . + . ID=gene-NBT03_gp049;Dbxref=GeneID:72551465;Name=OPG070;gbkey=Gene;gene=OPG070;gene_biotype=protein_coding;locus_tag=NBT03_gp049;old_locus_tag=MPXV-M5312_HM12_Rivers-054 +NC_063383.1 RefSeq CDS 50590 51411 . + 0 ID=cds-YP_010377053.1;Parent=gene-NBT03_gp049;Dbxref=GenBank:YP_010377053.1,GeneID:72551465;Name=OPG070;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp056%3B ER-localized membrane protein%2C virion core protein%3B similar to VACV-WR F7R and VACV-Cop E8R;gbkey=CDS;gene=OPG070;locus_tag=NBT03_gp049;product=Membrane protein E8;protein_id=YP_010377053.1 +NC_063383.1 RefSeq gene 51418 54438 . - . ID=gene-NBT03_gp050;Dbxref=GeneID:72551466;Name=OPG071;gbkey=Gene;gene=OPG071;gene_biotype=protein_coding;locus_tag=NBT03_gp050;old_locus_tag=MPXV-M5312_HM12_Rivers-055 +NC_063383.1 RefSeq CDS 51418 54438 . - 0 ID=cds-YP_010377054.1;Parent=gene-NBT03_gp050;Dbxref=GenBank:YP_010377054.1,GeneID:72551466;Name=OPG071;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp057%3B DNA polymerase%2C catalytic subunit%3B similar to VACV-WR F8L and VACV-Cop E9L;gbkey=CDS;gene=OPG071;locus_tag=NBT03_gp050;product=DNA polymerase (2);protein_id=YP_010377054.1 +NC_063383.1 RefSeq gene 54470 54757 . + . ID=gene-NBT03_gp051;Dbxref=GeneID:72551467;Name=OPG072;gbkey=Gene;gene=OPG072;gene_biotype=protein_coding;locus_tag=NBT03_gp051;old_locus_tag=MPXV-M5312_HM12_Rivers-056 +NC_063383.1 RefSeq CDS 54470 54757 . + 0 ID=cds-YP_010377055.1;Parent=gene-NBT03_gp051;Dbxref=GenBank:YP_010377055.1,GeneID:72551467;Name=OPG072;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp058%3B protein disulfide bond-forming enzyme%3B Sulfhydryl oxidase (FAD-linked)%3B similar to VACV-WR F9R and VACV-Cop E10R;gbkey=CDS;gene=OPG072;locus_tag=NBT03_gp051;product=Sulfhydryl oxidase;protein_id=YP_010377055.1 +NC_063383.1 RefSeq gene 54752 55141 . - . ID=gene-NBT03_gp052;Dbxref=GeneID:72551468;Name=OPG073;gbkey=Gene;gene=OPG073;gene_biotype=protein_coding;locus_tag=NBT03_gp052;old_locus_tag=MPXV-M5312_HM12_Rivers-057 +NC_063383.1 RefSeq CDS 54752 55141 . - 0 ID=cds-YP_010377056.1;Parent=gene-NBT03_gp052;Dbxref=GenBank:YP_010377056.1,GeneID:72551468;Name=OPG073;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp059%3B virion core protein%3B similar to VACV-WR F10L and VACV-Cop E11L;gbkey=CDS;gene=OPG073;locus_tag=NBT03_gp052;product=Virion core protein E11;protein_id=YP_010377056.1 +NC_063383.1 RefSeq gene 55128 57125 . - . ID=gene-NBT03_gp053;Dbxref=GeneID:72551469;Name=OPG074;gbkey=Gene;gene=OPG074;gene_biotype=protein_coding;locus_tag=NBT03_gp053;old_locus_tag=MPXV-M5312_HM12_Rivers-058 +NC_063383.1 RefSeq CDS 55128 57125 . - 0 ID=cds-YP_010377057.1;Parent=gene-NBT03_gp053;Dbxref=GenBank:YP_010377057.1,GeneID:72551469;Name=OPG074;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp060%3B Membrane protein%3B similar to VACV-WR Q1L and VACV-Cop O1L;gbkey=CDS;gene=OPG074;locus_tag=NBT03_gp053;product=Iev morphogenesis protein;protein_id=YP_010377057.1 +NC_063383.1 RefSeq gene 57172 57498 . - . ID=gene-NBT03_gp054;Dbxref=GeneID:72551470;Name=OPG075;gbkey=Gene;gene=OPG075;gene_biotype=protein_coding;locus_tag=NBT03_gp054;old_locus_tag=MPXV-M5312_HM12_Rivers-059 +NC_063383.1 RefSeq CDS 57172 57498 . - 0 ID=cds-YP_010377058.1;Parent=gene-NBT03_gp054;Dbxref=GenBank:YP_010377058.1,GeneID:72551470;Name=OPG075;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp061%3B virion-associated glutaredoxin%3B glutaredoxin 1%3B similar to VACV-WR Q2L and VACV-Cop O2L;gbkey=CDS;gene=OPG075;locus_tag=NBT03_gp054;product=Glutaredoxin-1;protein_id=YP_010377058.1 +NC_063383.1 RefSeq gene 57523 57630 . - . ID=gene-NBT03_gp055;Dbxref=GeneID:72551471;Name=OPG076;gbkey=Gene;gene=OPG076;gene_biotype=protein_coding;locus_tag=NBT03_gp055 +NC_063383.1 RefSeq CDS 57523 57630 . - 0 ID=cds-YP_010377183.1;Parent=gene-NBT03_gp055;Dbxref=GenBank:YP_010377183.1,GeneID:72551471;Name=OPG076;gbkey=CDS;gene=OPG076;locus_tag=NBT03_gp055;product=MV membrane EFC component;protein_id=YP_010377183.1 +NC_063383.1 RefSeq gene 57645 58583 . - . ID=gene-NBT03_gp056;Dbxref=GeneID:72551472;Name=OPG077;gbkey=Gene;gene=OPG077;gene_biotype=protein_coding;locus_tag=NBT03_gp056;old_locus_tag=MPXV-M5312_HM12_Rivers-060 +NC_063383.1 RefSeq CDS 57645 58583 . - 0 ID=cds-YP_010377059.1;Parent=gene-NBT03_gp056;Dbxref=GenBank:YP_010377059.1,GeneID:72551472;Name=OPG077;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp062%3B virosomal protein essential for virus multiplication%3B DNA-binding core protein%3B similar to VACV-WR I1L and VACV-Cop I1L;gbkey=CDS;gene=OPG077;locus_tag=NBT03_gp056;product=Telomere-binding protein I1;protein_id=YP_010377059.1 +NC_063383.1 RefSeq gene 58590 58811 . - . ID=gene-NBT03_gp057;Dbxref=GeneID:72551473;Name=OPG078;gbkey=Gene;gene=OPG078;gene_biotype=protein_coding;locus_tag=NBT03_gp057;old_locus_tag=MPXV-M5312_HM12_Rivers-061 +NC_063383.1 RefSeq CDS 58590 58811 . - 0 ID=cds-YP_010377060.1;Parent=gene-NBT03_gp057;Dbxref=GenBank:YP_010377060.1,GeneID:72551473;Name=OPG078;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp063%3B IMV membrane protein%3B similar to VACV-WR I2L and VACV-Cop I2L;gbkey=CDS;gene=OPG078;locus_tag=NBT03_gp057;product=IMV membrane protein I2;protein_id=YP_010377060.1 +NC_063383.1 RefSeq gene 58812 59621 . - . ID=gene-NBT03_gp058;Dbxref=GeneID:72551474;Name=OPG079;gbkey=Gene;gene=OPG079;gene_biotype=protein_coding;locus_tag=NBT03_gp058;old_locus_tag=MPXV-M5312_HM12_Rivers-062 +NC_063383.1 RefSeq CDS 58812 59621 . - 0 ID=cds-YP_010377061.1;Parent=gene-NBT03_gp058;Dbxref=GenBank:YP_010377061.1,GeneID:72551474;Name=OPG079;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp064%3B virosomal ssDNA-binding phosphoprotein%3B interacts with R2 subunit of ribonucleotide reductase%3B similar to VACV-WR I3L and VACV-Cop I3L;gbkey=CDS;gene=OPG079;locus_tag=NBT03_gp058;product=DNA-binding phosphoprotein (2);protein_id=YP_010377061.1 +NC_063383.1 RefSeq gene 59703 62018 . - . ID=gene-NBT03_gp059;Dbxref=GeneID:72551475;Name=OPG080;gbkey=Gene;gene=OPG080;gene_biotype=protein_coding;locus_tag=NBT03_gp059;old_locus_tag=MPXV-M5312_HM12_Rivers-063 +NC_063383.1 RefSeq CDS 59703 62018 . - 0 ID=cds-YP_010377062.1;Parent=gene-NBT03_gp059;Dbxref=GenBank:YP_010377062.1,GeneID:72551475;Name=OPG080;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp065%3B ribonucleotide reductase%2C large subunit%2C R1%3B similar to VACV-WR I4L and VACV-Cop I4L;gbkey=CDS;gene=OPG080;locus_tag=NBT03_gp059;product=Ribonucleoside-diphosphate reductase (2);protein_id=YP_010377062.1 +NC_063383.1 RefSeq gene 62046 62285 . - . ID=gene-NBT03_gp060;Dbxref=GeneID:72551476;Name=OPG081;gbkey=Gene;gene=OPG081;gene_biotype=protein_coding;locus_tag=NBT03_gp060;old_locus_tag=MPXV-M5312_HM12_Rivers-064 +NC_063383.1 RefSeq CDS 62046 62285 . - 0 ID=cds-YP_010377063.1;Parent=gene-NBT03_gp060;Dbxref=GenBank:YP_010377063.1,GeneID:72551476;Name=OPG081;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp066%3B IMV surface membrane protein%2C VP13%3B similar to VACV-WR I5L and VACV-Cop I5L;gbkey=CDS;gene=OPG081;locus_tag=NBT03_gp060;product=IMV membrane protein I5;protein_id=YP_010377063.1 +NC_063383.1 RefSeq gene 62304 63452 . - . ID=gene-NBT03_gp061;Dbxref=GeneID:72551477;Name=OPG082;gbkey=Gene;gene=OPG082;gene_biotype=protein_coding;locus_tag=NBT03_gp061;old_locus_tag=MPXV-M5312_HM12_Rivers-065 +NC_063383.1 RefSeq CDS 62304 63452 . - 0 ID=cds-YP_010377064.1;Parent=gene-NBT03_gp061;Dbxref=GenBank:YP_010377064.1,GeneID:72551477;Name=OPG082;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp067%3B Telomere-binding protein%3B similar to VACV-WR I6L and VACV-Cop I6L;gbkey=CDS;gene=OPG082;locus_tag=NBT03_gp061;product=Telomere-binding protein;protein_id=YP_010377064.1 +NC_063383.1 RefSeq gene 63445 64716 . - . ID=gene-NBT03_gp062;Dbxref=GeneID:72551478;Name=OPG083;gbkey=Gene;gene=OPG083;gene_biotype=protein_coding;locus_tag=NBT03_gp062;old_locus_tag=MPXV-M5312_HM12_Rivers-066 +NC_063383.1 RefSeq CDS 63445 64716 . - 0 ID=cds-YP_010377065.1;Parent=gene-NBT03_gp062;Dbxref=GenBank:YP_010377065.1,GeneID:72551478;Name=OPG083;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp068%3B virion core protein%3B similar to DNA topoisomerase II%3B Virion core cysteine protease%3B similar to VACV-WR I7L and VACV-Cop I7L;gbkey=CDS;gene=OPG083;locus_tag=NBT03_gp062;product=Viral core cysteine proteinase;protein_id=YP_010377065.1 +NC_063383.1 RefSeq gene 64722 66752 . + . ID=gene-NBT03_gp063;Dbxref=GeneID:72551479;Name=OPG084;gbkey=Gene;gene=OPG084;gene_biotype=protein_coding;locus_tag=NBT03_gp063;old_locus_tag=MPXV-M5312_HM12_Rivers-067 +NC_063383.1 RefSeq CDS 64722 66752 . + 0 ID=cds-YP_010377066.1;Parent=gene-NBT03_gp063;Dbxref=GenBank:YP_010377066.1,GeneID:72551479;Name=OPG084;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp069%3B nucleoside triphosphate phosphohydrolase II%2C NPH-II%3B DNA and RNA helicase%3B DExH-NPH-II domain%3B similar to VACV-WR I8R and VACV-Cop I8R;gbkey=CDS;gene=OPG084;locus_tag=NBT03_gp063;product=RNA helicase NPH-II (2);protein_id=YP_010377066.1 +NC_063383.1 RefSeq gene 66756 68531 . - . ID=gene-NBT03_gp064;Dbxref=GeneID:72551480;Name=OPG085;gbkey=Gene;gene=OPG085;gene_biotype=protein_coding;locus_tag=NBT03_gp064;old_locus_tag=MPXV-M5312_HM12_Rivers-068 +NC_063383.1 RefSeq CDS 66756 68531 . - 0 ID=cds-YP_010377067.1;Parent=gene-NBT03_gp064;Dbxref=GenBank:YP_010377067.1,GeneID:72551480;Name=OPG085;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp070%3B proteinase%3B Metalloprotease%3B similar to VACV-WR G1L and VACV-Cop G1L;gbkey=CDS;gene=OPG085;locus_tag=NBT03_gp064;product=Metalloendopeptidase;protein_id=YP_010377067.1 +NC_063383.1 RefSeq gene 68528 68863 . - . ID=gene-NBT03_gp065;Dbxref=GeneID:72551481;Name=OPG086;gbkey=Gene;gene=OPG086;gene_biotype=protein_coding;locus_tag=NBT03_gp065;old_locus_tag=MPXV-M5312_HM12_Rivers-069 +NC_063383.1 RefSeq CDS 68528 68863 . - 0 ID=cds-YP_010377068.1;Parent=gene-NBT03_gp065;Dbxref=GenBank:YP_010377068.1,GeneID:72551481;Name=OPG086;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp071%3B Entry/fusion complex component%3B similar to VACV-WR G2L and VACV-Cop G3L;gbkey=CDS;gene=OPG086;locus_tag=NBT03_gp065;product=Entry/fusion complex component;protein_id=YP_010377068.1 +NC_063383.1 RefSeq gene 68857 69519 . + . ID=gene-NBT03_gp066;Dbxref=GeneID:72551482;Name=OPG087;gbkey=Gene;gene=OPG087;gene_biotype=protein_coding;locus_tag=NBT03_gp066;old_locus_tag=MPXV-M5312_HM12_Rivers-070 +NC_063383.1 RefSeq CDS 68857 69519 . + 0 ID=cds-YP_010377069.1;Parent=gene-NBT03_gp066;Dbxref=GenBank:YP_010377069.1,GeneID:72551482;Name=OPG087;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp072%3B VLTF (late transcription elongation factor)%3B similar to VACV-WR G3R and VACV-Cop G2R;gbkey=CDS;gene=OPG087;locus_tag=NBT03_gp066;product=Late transcription elongation factor;protein_id=YP_010377069.1 +NC_063383.1 RefSeq gene 69489 69863 . - . ID=gene-NBT03_gp067;Dbxref=GeneID:72551483;Name=OPG088;gbkey=Gene;gene=OPG088;gene_biotype=protein_coding;locus_tag=NBT03_gp067;old_locus_tag=MPXV-M5312_HM12_Rivers-071 +NC_063383.1 RefSeq CDS 69489 69863 . - 0 ID=cds-YP_010377070.1;Parent=gene-NBT03_gp067;Dbxref=GenBank:YP_010377070.1,GeneID:72551483;Name=OPG088;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp073%3B virion-associated glutaredoxin%3B Glutaredoxin-like protein%3B similar to VACV-WR G4L and VACV-Cop G4L;gbkey=CDS;gene=OPG088;locus_tag=NBT03_gp067;product=Glutaredoxin-2;protein_id=YP_010377070.1 +NC_063383.1 RefSeq gene 69866 71170 . + . ID=gene-NBT03_gp068;Dbxref=GeneID:72551484;Name=OPG089;gbkey=Gene;gene=OPG089;gene_biotype=protein_coding;locus_tag=NBT03_gp068;old_locus_tag=MPXV-M5312_HM12_Rivers-072 +NC_063383.1 RefSeq CDS 69866 71170 . + 0 ID=cds-YP_010377071.1;Parent=gene-NBT03_gp068;Dbxref=GenBank:YP_010377071.1,GeneID:72551484;Name=OPG089;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp074%3B FEN1-like nuclease%3B similar to VACV-WR G5R and VACV-Cop G5R;gbkey=CDS;gene=OPG089;locus_tag=NBT03_gp068;product=FEN1-like nuclease;protein_id=YP_010377071.1 +NC_063383.1 RefSeq gene 71179 71370 . + . ID=gene-NBT03_gp069;Dbxref=GeneID:72551485;Name=OPG090;gbkey=Gene;gene=OPG090;gene_biotype=protein_coding;locus_tag=NBT03_gp069;old_locus_tag=MPXV-M5312_HM12_Rivers-073 +NC_063383.1 RefSeq CDS 71179 71370 . + 0 ID=cds-YP_010377072.1;Parent=gene-NBT03_gp069;Dbxref=GenBank:YP_010377072.1,GeneID:72551485;Name=OPG090;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp075%3B RNA polymerase subunit%2C 7 kDa subunit (RPO7)%3B similar to VACV-WR G6R and VACV-Cop G5.5R;gbkey=CDS;gene=OPG090;locus_tag=NBT03_gp069;product=DNA-directed RNA polymerase 7 kDa subunit;protein_id=YP_010377072.1 +NC_063383.1 RefSeq gene 71370 71867 . + . ID=gene-NBT03_gp070;Dbxref=GeneID:72551486;Name=OPG091;gbkey=Gene;gene=OPG091;gene_biotype=protein_coding;locus_tag=NBT03_gp070;old_locus_tag=MPXV-M5312_HM12_Rivers-074 +NC_063383.1 RefSeq CDS 71370 71867 . + 0 ID=cds-YP_010377073.1;Parent=gene-NBT03_gp070;Dbxref=GenBank:YP_010377073.1,GeneID:72551486;Name=OPG091;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp076%3B NLPc/P60 superfamily protein%3B similar to VACV-WR G7R and VACV-Cop G6R;gbkey=CDS;gene=OPG091;locus_tag=NBT03_gp070;product=Nlpc/p60 superfamily protein;protein_id=YP_010377073.1 +NC_063383.1 RefSeq gene 71832 72947 . - . ID=gene-NBT03_gp071;Dbxref=GeneID:72551487;Name=OPG092;gbkey=Gene;gene=OPG092;gene_biotype=protein_coding;locus_tag=NBT03_gp071;old_locus_tag=MPXV-M5312_HM12_Rivers-075 +NC_063383.1 RefSeq CDS 71832 72947 . - 0 ID=cds-YP_010377074.1;Parent=gene-NBT03_gp071;Dbxref=GenBank:YP_010377074.1,GeneID:72551487;Name=OPG092;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp077%3B virion protein%3B Virion phosphoprotein%2C early morphogenesis%3B similar to VACV-WR G8L and VACV-Cop G7L;gbkey=CDS;gene=OPG092;locus_tag=NBT03_gp071;product=Assembly protein G7;protein_id=YP_010377074.1 +NC_063383.1 RefSeq gene 72978 73760 . + . ID=gene-NBT03_gp072;Dbxref=GeneID:72551488;Name=OPG093;gbkey=Gene;gene=OPG093;gene_biotype=protein_coding;locus_tag=NBT03_gp072;old_locus_tag=MPXV-M5312_HM12_Rivers-076 +NC_063383.1 RefSeq CDS 72978 73760 . + 0 ID=cds-YP_010377075.1;Parent=gene-NBT03_gp072;Dbxref=GenBank:YP_010377075.1,GeneID:72551488;Name=OPG093;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp078%3B late gene transcription factor%2C VLTF-1%3B similar to VACV-WR G9R and VACV-Cop G8R;gbkey=CDS;gene=OPG093;locus_tag=NBT03_gp072;product=Late transcription factor VLTF-1;protein_id=YP_010377075.1 +NC_063383.1 RefSeq gene 73780 74802 . + . ID=gene-NBT03_gp073;Dbxref=GeneID:72551489;Name=OPG094;gbkey=Gene;gene=OPG094;gene_biotype=protein_coding;locus_tag=NBT03_gp073;old_locus_tag=MPXV-M5312_HM12_Rivers-077 +NC_063383.1 RefSeq CDS 73780 74802 . + 0 ID=cds-YP_010377076.1;Parent=gene-NBT03_gp073;Dbxref=GenBank:YP_010377076.1,GeneID:72551489;Name=OPG094;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp079%3B myristylated protein%3B Entry/fusion complex component%2C myristylprotein%3B similar to VACV-WR G10R and VACV-Cop G9R;gbkey=CDS;gene=OPG094;locus_tag=NBT03_gp073;product=Myristylated protein;protein_id=YP_010377076.1 +NC_063383.1 RefSeq gene 74803 75555 . + . ID=gene-NBT03_gp074;Dbxref=GeneID:72551490;Name=OPG095;gbkey=Gene;gene=OPG095;gene_biotype=protein_coding;locus_tag=NBT03_gp074;old_locus_tag=MPXV-M5312_HM12_Rivers-078 +NC_063383.1 RefSeq CDS 74803 75555 . + 0 ID=cds-YP_010377077.1;Parent=gene-NBT03_gp074;Dbxref=GenBank:YP_010377077.1,GeneID:72551490;Name=OPG095;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp080%3B myristylated IMV surface membrane protein%3B similar to VACV-WR M1R and VACV-Cop L1R;gbkey=CDS;gene=OPG095;locus_tag=NBT03_gp074;product=IMV membrane protein L1R;protein_id=YP_010377077.1 +NC_063383.1 RefSeq gene 75587 75865 . + . ID=gene-NBT03_gp075;Dbxref=GeneID:72551491;Name=OPG096;gbkey=Gene;gene=OPG096;gene_biotype=protein_coding;locus_tag=NBT03_gp075;old_locus_tag=MPXV-M5312_HM12_Rivers-079 +NC_063383.1 RefSeq CDS 75587 75865 . + 0 ID=cds-YP_010377078.1;Parent=gene-NBT03_gp075;Dbxref=GenBank:YP_010377078.1,GeneID:72551491;Name=OPG096;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp081%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR M2R and VACV-Cop L2R;gbkey=CDS;gene=OPG096;locus_tag=NBT03_gp075;product=Crescent membrane and immature virion formation protein;protein_id=YP_010377078.1 +NC_063383.1 RefSeq gene 75841 76875 . - . ID=gene-NBT03_gp076;Dbxref=GeneID:72551492;Name=OPG097;gbkey=Gene;gene=OPG097;gene_biotype=protein_coding;locus_tag=NBT03_gp076;old_locus_tag=MPXV-M5312_HM12_Rivers-080 +NC_063383.1 RefSeq CDS 75841 76875 . - 0 ID=cds-YP_010377079.1;Parent=gene-NBT03_gp076;Dbxref=GenBank:YP_010377079.1,GeneID:72551492;Name=OPG097;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp082%3B Internal virion protein%3B similar to VACV-WR M3L and VACV-Cop L3L;gbkey=CDS;gene=OPG097;locus_tag=NBT03_gp076;product=Internal virion L3/FP4 protein;protein_id=YP_010377079.1 +NC_063383.1 RefSeq gene 76900 77655 . + . ID=gene-NBT03_gp077;Dbxref=GeneID:72551493;Name=OPG098;gbkey=Gene;gene=OPG098;gene_biotype=protein_coding;locus_tag=NBT03_gp077;old_locus_tag=MPXV-M5312_HM12_Rivers-081 +NC_063383.1 RefSeq CDS 76900 77655 . + 0 ID=cds-YP_010377080.1;Parent=gene-NBT03_gp077;Dbxref=GenBank:YP_010377080.1,GeneID:72551493;Name=OPG098;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp083%3B virion core protein vp8%3B stimulation of I8R helicase activity%3B ss/dsDNA binding protein (VP8)%3B similar to VACV-WR M4R and VACV-Cop L4R;gbkey=CDS;gene=OPG098;locus_tag=NBT03_gp077;product=Nucleic acid binding protein VP8/L4R;protein_id=YP_010377080.1 +NC_063383.1 RefSeq gene 77665 78051 . + . ID=gene-NBT03_gp078;Dbxref=GeneID:72551494;Name=OPG099;gbkey=Gene;gene=OPG099;gene_biotype=protein_coding;locus_tag=NBT03_gp078;old_locus_tag=MPXV-M5312_HM12_Rivers-082 +NC_063383.1 RefSeq CDS 77665 78051 . + 0 ID=cds-YP_010377081.1;Parent=gene-NBT03_gp078;Dbxref=GenBank:YP_010377081.1,GeneID:72551494;Name=OPG099;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp084%3B Entry and Fusion IMV protein%3B similar to VACV-WR M5R and VACV-Cop L5R;gbkey=CDS;gene=OPG099;locus_tag=NBT03_gp078;product=Membrane protein CL5;protein_id=YP_010377081.1 +NC_063383.1 RefSeq gene 78008 78466 . + . ID=gene-NBT03_gp079;Dbxref=GeneID:72551495;Name=OPG100;gbkey=Gene;gene=OPG100;gene_biotype=protein_coding;locus_tag=NBT03_gp079;old_locus_tag=MPXV-M5312_HM12_Rivers-083 +NC_063383.1 RefSeq CDS 78008 78466 . + 0 ID=cds-YP_010377082.1;Parent=gene-NBT03_gp079;Dbxref=GenBank:YP_010377082.1,GeneID:72551495;Name=OPG100;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp085%3B Virion morph%3B similar to VACV-WR L1R and VACV-Cop J1R;gbkey=CDS;gene=OPG100;locus_tag=NBT03_gp079;product=IMV membrane protein J1;protein_id=YP_010377082.1 +NC_063383.1 RefSeq gene 78486 79019 . + . ID=gene-NBT03_gp080;Dbxref=GeneID:72551496;Name=OPG101;gbkey=Gene;gene=OPG101;gene_biotype=protein_coding;locus_tag=NBT03_gp080;old_locus_tag=MPXV-M5312_HM12_Rivers-084 +NC_063383.1 RefSeq CDS 78486 79019 . + 0 ID=cds-YP_010377083.1;Parent=gene-NBT03_gp080;Dbxref=GenBank:YP_010377083.1,GeneID:72551496;Name=OPG101;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp086%3B thymidine kinase%3B similar to VACV-WR L2R and VACV-Cop J2R;gbkey=CDS;gene=OPG101;locus_tag=NBT03_gp080;product=Thymidine kinase;protein_id=YP_010377083.1 +NC_063383.1 RefSeq gene 79085 80086 . + . ID=gene-NBT03_gp081;Dbxref=GeneID:72551497;Name=OPG102;gbkey=Gene;gene=OPG102;gene_biotype=protein_coding;locus_tag=NBT03_gp081;old_locus_tag=MPXV-M5312_HM12_Rivers-085 +NC_063383.1 RefSeq CDS 79085 80086 . + 0 ID=cds-YP_010377084.1;Parent=gene-NBT03_gp081;Dbxref=GenBank:YP_010377084.1,GeneID:72551497;Name=OPG102;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp087%3B poly-A polymerase%2C stimulatory subunit%2C simultaneously cap-specific mRNA (nucleoside-O2'-)-methyltransferase%3B Poly (A) polymerase small subunit (VP39)%3B similar to VACV-WR L3R and VACV-Cop J3R;gbkey=CDS;gene=OPG102;locus_tag=NBT03_gp081;product=Cap-specific mRNA;protein_id=YP_010377084.1 +NC_063383.1 RefSeq gene 80001 80558 . + . ID=gene-NBT03_gp082;Dbxref=GeneID:72551498;Name=OPG103;gbkey=Gene;gene=OPG103;gene_biotype=protein_coding;locus_tag=NBT03_gp082;old_locus_tag=MPXV-M5312_HM12_Rivers-086 +NC_063383.1 RefSeq CDS 80001 80558 . + 0 ID=cds-YP_010377085.1;Parent=gene-NBT03_gp082;Dbxref=GenBank:YP_010377085.1,GeneID:72551498;Name=OPG103;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp088%3B RNA polymerase%2C 22 kDa subunit (RPO22)%3B similar to VACV-WR L4R and VACV-Cop J4R;gbkey=CDS;gene=OPG103;locus_tag=NBT03_gp082;product=DNA-directed RNA polymerase subunit;protein_id=YP_010377085.1 +NC_063383.1 RefSeq gene 80618 81019 . - . ID=gene-NBT03_gp083;Dbxref=GeneID:72551499;Name=OPG104;gbkey=Gene;gene=OPG104;gene_biotype=protein_coding;locus_tag=NBT03_gp083;old_locus_tag=MPXV-M5312_HM12_Rivers-087 +NC_063383.1 RefSeq CDS 80618 81019 . - 0 ID=cds-YP_010377086.1;Parent=gene-NBT03_gp083;Dbxref=GenBank:YP_010377086.1,GeneID:72551499;Name=OPG104;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp089%3B essential for virus multiplication%3B IMV membrane protein%3B similar to VACV-WR L5L and VACV-Cop J5L;gbkey=CDS;gene=OPG104;locus_tag=NBT03_gp083;product=Myristylated protein;protein_id=YP_010377086.1 +NC_063383.1 RefSeq gene 81126 84986 . + . ID=gene-NBT03_gp084;Dbxref=GeneID:72551500;Name=OPG105;gbkey=Gene;gene=OPG105;gene_biotype=protein_coding;locus_tag=NBT03_gp084;old_locus_tag=MPXV-M5312_HM12_Rivers-088 +NC_063383.1 RefSeq CDS 81126 84986 . + 0 ID=cds-YP_010377087.1;Parent=gene-NBT03_gp084;Dbxref=GenBank:YP_010377087.1,GeneID:72551500;Name=OPG105;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp090%3B RNA polymerase%2C 147 kDa subunit (RPO147)%3B similar to VACV-WR L6R and VACV-Cop J6R;gbkey=CDS;gene=OPG105;locus_tag=NBT03_gp084;product=DNA-dependent RNA polymerase subunit rpo147;protein_id=YP_010377087.1 +NC_063383.1 RefSeq gene 84983 85498 . - . ID=gene-NBT03_gp085;Dbxref=GeneID:72551501;Name=OPG106;gbkey=Gene;gene=OPG106;gene_biotype=protein_coding;locus_tag=NBT03_gp085;old_locus_tag=MPXV-M5312_HM12_Rivers-089 +NC_063383.1 RefSeq CDS 84983 85498 . - 0 ID=cds-YP_010377088.1;Parent=gene-NBT03_gp085;Dbxref=GenBank:YP_010377088.1,GeneID:72551501;Name=OPG106;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp091%3B tyrosine%3B Tyr/Ser phosphatase%2C IFN-gamma inhibitor%3B similar to VACV-WR H1L and VACV-Cop H1L;gbkey=CDS;gene=OPG106;locus_tag=NBT03_gp085;product=Tyr/ser protein phosphatase;protein_id=YP_010377088.1 +NC_063383.1 RefSeq gene 85512 86081 . + . ID=gene-NBT03_gp086;Dbxref=GeneID:72551502;Name=OPG107;gbkey=Gene;gene=OPG107;gene_biotype=protein_coding;locus_tag=NBT03_gp086;old_locus_tag=MPXV-M5312_HM12_Rivers-090 +NC_063383.1 RefSeq CDS 85512 86081 . + 0 ID=cds-YP_010377089.1;Parent=gene-NBT03_gp086;Dbxref=GenBank:YP_010377089.1,GeneID:72551502;Name=OPG107;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp092%3B IMV membrane protein%3B similar to VACV-WR H2R and VACV-Cop H2R;gbkey=CDS;gene=OPG107;locus_tag=NBT03_gp086;product=Entry-fusion complex essential component;protein_id=YP_010377089.1 +NC_063383.1 RefSeq gene 86085 87059 . - . ID=gene-NBT03_gp087;Dbxref=GeneID:72551503;Name=OPG108;gbkey=Gene;gene=OPG108;gene_biotype=protein_coding;locus_tag=NBT03_gp087;old_locus_tag=MPXV-M5312_HM12_Rivers-091 +NC_063383.1 RefSeq CDS 86085 87059 . - 0 ID=cds-YP_010377090.1;Parent=gene-NBT03_gp087;Dbxref=GenBank:YP_010377090.1,GeneID:72551503;Name=OPG108;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp093%3B IMV surface membrane protein%3B IMV heparin binding surface protein%3B similar to VACV-WR H3L and VACV-Cop H3L;gbkey=CDS;gene=OPG108;locus_tag=NBT03_gp087;product=IMV heparin binding surface protein;protein_id=YP_010377090.1 +NC_063383.1 RefSeq gene 87060 89447 . - . ID=gene-NBT03_gp088;Dbxref=GeneID:72551504;Name=OPG109;gbkey=Gene;gene=OPG109;gene_biotype=protein_coding;locus_tag=NBT03_gp088;old_locus_tag=MPXV-M5312_HM12_Rivers-092 +NC_063383.1 RefSeq CDS 87060 89447 . - 0 ID=cds-YP_010377091.1;Parent=gene-NBT03_gp088;Dbxref=GenBank:YP_010377091.1,GeneID:72551504;Name=OPG109;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp094%3B virion core RNA polymerase-associated protein%2C RAP94%3B similar to VACV-WR H4L and VACV-Cop H4L;gbkey=CDS;gene=OPG109;locus_tag=NBT03_gp088;product=RNA polymerase-associated transcription-specificity factor RAP94;protein_id=YP_010377091.1 +NC_063383.1 RefSeq gene 89632 90264 . + . ID=gene-NBT03_gp089;Dbxref=GeneID:72551505;Name=OPG110;gbkey=Gene;gene=OPG110;gene_biotype=protein_coding;locus_tag=NBT03_gp089;old_locus_tag=MPXV-M5312_HM12_Rivers-093 +NC_063383.1 RefSeq CDS 89632 90264 . + 0 ID=cds-YP_010377092.1;Parent=gene-NBT03_gp089;Dbxref=GenBank:YP_010377092.1,GeneID:72551505;Name=OPG110;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp095%3B virosome-associated late gene transcription factor%2C VLTF-4%3B Ca2+-binding motif%3B similar to VACV-WR H5R and VACV-Cop H5R;gbkey=CDS;gene=OPG110;locus_tag=NBT03_gp089;product=Late transcription factor VLTF-4 (1);protein_id=YP_010377092.1 +NC_063383.1 RefSeq gene 90265 91209 . + . ID=gene-NBT03_gp090;Dbxref=GeneID:72551506;Name=OPG111;gbkey=Gene;gene=OPG111;gene_biotype=protein_coding;locus_tag=NBT03_gp090;old_locus_tag=MPXV-M5312_HM12_Rivers-094 +NC_063383.1 RefSeq CDS 90265 91209 . + 0 ID=cds-YP_010377093.1;Parent=gene-NBT03_gp090;Dbxref=GenBank:YP_010377093.1,GeneID:72551506;Name=OPG111;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp096%3B DNA topoisomerase type I%3B similar to VACV-WR H6R and VACV-Cop H6R;gbkey=CDS;gene=OPG111;locus_tag=NBT03_gp090;product=DNA topoisomerase type I;protein_id=YP_010377093.1 +NC_063383.1 RefSeq gene 91247 91687 . + . ID=gene-NBT03_gp091;Dbxref=GeneID:72551507;Name=OPG112;gbkey=Gene;gene=OPG112;gene_biotype=protein_coding;locus_tag=NBT03_gp091;old_locus_tag=MPXV-M5312_HM12_Rivers-095 +NC_063383.1 RefSeq CDS 91247 91687 . + 0 ID=cds-YP_010377094.1;Parent=gene-NBT03_gp091;Dbxref=GenBank:YP_010377094.1,GeneID:72551507;Name=OPG112;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp097%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR H7R and VACV-Cop H7R;gbkey=CDS;gene=OPG112;locus_tag=NBT03_gp091;product=Late protein H7;protein_id=YP_010377094.1 +NC_063383.1 RefSeq gene 91731 94268 . + . ID=gene-NBT03_gp092;Dbxref=GeneID:72551508;Name=OPG113;gbkey=Gene;gene=OPG113;gene_biotype=protein_coding;locus_tag=NBT03_gp092;old_locus_tag=MPXV-M5312_HM12_Rivers-096 +NC_063383.1 RefSeq CDS 91731 94268 . + 0 ID=cds-YP_010377095.1;Parent=gene-NBT03_gp092;Dbxref=GenBank:YP_010377095.1,GeneID:72551508;Name=OPG113;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp098%3B mRNA capping enzyme%2C large subunit%3B RNA 5' triphosphatase and RNA guanylyl transferase activities%3B similar to VACV-WR E1R and VACV-Cop D1R;gbkey=CDS;gene=OPG113;locus_tag=NBT03_gp092;product=mRNA capping enzyme large subunit;protein_id=YP_010377095.1 +NC_063383.1 RefSeq gene 94227 94667 . - . ID=gene-NBT03_gp093;Dbxref=GeneID:72551509;Name=OPG114;gbkey=Gene;gene=OPG114;gene_biotype=protein_coding;locus_tag=NBT03_gp093;old_locus_tag=MPXV-M5312_HM12_Rivers-097 +NC_063383.1 RefSeq CDS 94227 94667 . - 0 ID=cds-YP_010377096.1;Parent=gene-NBT03_gp093;Dbxref=GenBank:YP_010377096.1,GeneID:72551509;Name=OPG114;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp099%3B virion core protein%3B similar to VACV-WR E2L and VACV-Cop D2L;gbkey=CDS;gene=OPG114;locus_tag=NBT03_gp093;product=Virion protein D2;protein_id=YP_010377096.1 +NC_063383.1 RefSeq gene 94660 95361 . + . ID=gene-NBT03_gp094;Dbxref=GeneID:72551510;Name=OPG115;gbkey=Gene;gene=OPG115;gene_biotype=protein_coding;locus_tag=NBT03_gp094;old_locus_tag=MPXV-M5312_HM12_Rivers-098 +NC_063383.1 RefSeq CDS 94660 95361 . + 0 ID=cds-YP_010377097.1;Parent=gene-NBT03_gp094;Dbxref=GenBank:YP_010377097.1,GeneID:72551510;Name=OPG115;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp100%3B virion core protein%3B similar to VACV-WR E3R and VACV-Cop D3R;gbkey=CDS;gene=OPG115;locus_tag=NBT03_gp094;product=Virion core protein D3;protein_id=YP_010377097.1 +NC_063383.1 RefSeq gene 95361 96017 . + . ID=gene-NBT03_gp095;Dbxref=GeneID:72551511;Name=OPG116;gbkey=Gene;gene=OPG116;gene_biotype=protein_coding;locus_tag=NBT03_gp095;old_locus_tag=MPXV-M5312_HM12_Rivers-099 +NC_063383.1 RefSeq CDS 95361 96017 . + 0 ID=cds-YP_010377098.1;Parent=gene-NBT03_gp095;Dbxref=GenBank:YP_010377098.1,GeneID:72551511;Name=OPG116;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp101%3B uracil DNA glycosylase%3B DNA polymerase processivity factor%3B similar to VACV-WR E4R and VACV-Cop D4R;gbkey=CDS;gene=OPG116;locus_tag=NBT03_gp095;product=Uracil DNA glycosylase superfamily;protein_id=YP_010377098.1 +NC_063383.1 RefSeq gene 96049 98406 . + . ID=gene-NBT03_gp096;Dbxref=GeneID:72551512;Name=OPG117;gbkey=Gene;gene=OPG117;gene_biotype=protein_coding;locus_tag=NBT03_gp096;old_locus_tag=MPXV-M5312_HM12_Rivers-100 +NC_063383.1 RefSeq CDS 96049 98406 . + 0 ID=cds-YP_010377099.1;Parent=gene-NBT03_gp096;Dbxref=GenBank:YP_010377099.1,GeneID:72551512;Name=OPG117;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp102%3B nucleic acid-independent nucleoside triphosphatase%3B NTPase%2C DNA primase%3B similar to VACV-WR E5R and VACV-Cop D5R;gbkey=CDS;gene=OPG117;locus_tag=NBT03_gp096;product=NTPase (1);protein_id=YP_010377099.1 +NC_063383.1 RefSeq gene 98446 100359 . + . ID=gene-NBT03_gp097;Dbxref=GeneID:72551513;Name=OPG118;gbkey=Gene;gene=OPG118;gene_biotype=protein_coding;locus_tag=NBT03_gp097;old_locus_tag=MPXV-M5312_HM12_Rivers-101 +NC_063383.1 RefSeq CDS 98446 100359 . + 0 ID=cds-YP_010377100.1;Parent=gene-NBT03_gp097;Dbxref=GenBank:YP_010377100.1,GeneID:72551513;Name=OPG118;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp103%3B early transcription factor%2C small subunit%2C VETF-s%3B Morphogenesis%3B similar to VACV-WR E6R and VACV-Cop D6R;gbkey=CDS;gene=OPG118;locus_tag=NBT03_gp097;product=Early transcription factor 70 kDa subunit;protein_id=YP_010377100.1 +NC_063383.1 RefSeq gene 100386 100871 . + . ID=gene-NBT03_gp098;Dbxref=GeneID:72551514;Name=OPG119;gbkey=Gene;gene=OPG119;gene_biotype=protein_coding;locus_tag=NBT03_gp098;old_locus_tag=MPXV-M5312_HM12_Rivers-102 +NC_063383.1 RefSeq CDS 100386 100871 . + 0 ID=cds-YP_010377101.1;Parent=gene-NBT03_gp098;Dbxref=GenBank:YP_010377101.1,GeneID:72551514;Name=OPG119;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp104%3B RNA polymerase%2C 18 kDa subunit (RPO18)%3B similar to VACV-WR E7R and VACV-Cop D7R;gbkey=CDS;gene=OPG119;locus_tag=NBT03_gp098;product=RNA polymerase subunit RPO18;protein_id=YP_010377101.1 +NC_063383.1 RefSeq gene 100834 101748 . - . ID=gene-NBT03_gp099;Dbxref=GeneID:72551515;Name=OPG120;gbkey=Gene;gene=OPG120;gene_biotype=protein_coding;locus_tag=NBT03_gp099;old_locus_tag=MPXV-M5312_HM12_Rivers-103 +NC_063383.1 RefSeq CDS 100834 101748 . - 0 ID=cds-YP_010377102.1;Parent=gene-NBT03_gp099;Dbxref=GenBank:YP_010377102.1,GeneID:72551515;Name=OPG120;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp105%3B IMV surface membrane 32 kDa protein%3B binding to cell surface chondroitin sulfate%3B IMV adsorption to cell surface%3B GAG-binding IMV membrane protein%3B similar to VACV-WR E8L and VACV-Cop D8L;gbkey=CDS;gene=OPG120;locus_tag=NBT03_gp099;product=Carbonic anhydrase;protein_id=YP_010377102.1 +NC_063383.1 RefSeq gene 101790 102431 . + . ID=gene-NBT03_gp100;Dbxref=GeneID:72551516;Name=OPG121;gbkey=Gene;gene=OPG121;gene_biotype=protein_coding;locus_tag=NBT03_gp100;old_locus_tag=MPXV-M5312_HM12_Rivers-104 +NC_063383.1 RefSeq CDS 101790 102431 . + 0 ID=cds-YP_010377103.1;Parent=gene-NBT03_gp100;Dbxref=GenBank:YP_010377103.1,GeneID:72551516;Name=OPG121;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp106%3B Mut-like%3B mRNA decapping enzyme%3B similar to VACV-WR E9R and VACV-Cop D9R;gbkey=CDS;gene=OPG121;locus_tag=NBT03_gp100;product=NUDIX domain protein;protein_id=YP_010377103.1 +NC_063383.1 RefSeq gene 102428 103174 . + . ID=gene-NBT03_gp101;Dbxref=GeneID:72551517;Name=OPG122;gbkey=Gene;gene=OPG122;gene_biotype=protein_coding;locus_tag=NBT03_gp101;old_locus_tag=MPXV-M5312_HM12_Rivers-105 +NC_063383.1 RefSeq CDS 102428 103174 . + 0 ID=cds-YP_010377104.1;Parent=gene-NBT03_gp101;Dbxref=GenBank:YP_010377104.1,GeneID:72551517;Name=OPG122;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp107%3B down regulation of gene expression%3B Mut-like%3B mRNA decapping enzyme%3B similar to VACV-WR E10R and VACV-Cop D10R;gbkey=CDS;gene=OPG122;locus_tag=NBT03_gp101;product=MutT motif protein;protein_id=YP_010377104.1 +NC_063383.1 RefSeq gene 103175 105070 . - . ID=gene-NBT03_gp102;Dbxref=GeneID:72551518;Name=OPG123;gbkey=Gene;gene=OPG123;gene_biotype=protein_coding;locus_tag=NBT03_gp102;old_locus_tag=MPXV-M5312_HM12_Rivers-106 +NC_063383.1 RefSeq CDS 103175 105070 . - 0 ID=cds-YP_010377105.1;Parent=gene-NBT03_gp102;Dbxref=GenBank:YP_010377105.1,GeneID:72551518;Name=OPG123;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp108%3B nucleoside triphosphate phosphohydrolase I%2C NPH I%3B DNA-dependent ATPase%3B early gene transcription termination factor%3B similar to VACV-WR E11L and VACV-Cop D11L;gbkey=CDS;gene=OPG123;locus_tag=NBT03_gp102;product=Nucleoside triphosphatase I;protein_id=YP_010377105.1 +NC_063383.1 RefSeq gene 105105 105968 . - . ID=gene-NBT03_gp103;Dbxref=GeneID:72551519;Name=OPG124;gbkey=Gene;gene=OPG124;gene_biotype=protein_coding;locus_tag=NBT03_gp103;old_locus_tag=MPXV-M5312_HM12_Rivers-107 +NC_063383.1 RefSeq CDS 105105 105968 . - 0 ID=cds-YP_010377106.1;Parent=gene-NBT03_gp103;Dbxref=GenBank:YP_010377106.1,GeneID:72551519;Name=OPG124;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp109%3B mRNA capping enzyme small subunit%3B mRNA (guanine-N7-)-methyl-transferase%3B transcription initiation factor%3B similar to VACV-WR E12L and VACV-Cop D12L;gbkey=CDS;gene=OPG124;locus_tag=NBT03_gp103;product=mRNA capping enzyme small subunit;protein_id=YP_010377106.1 +NC_063383.1 RefSeq gene 105999 107654 . - . ID=gene-NBT03_gp104;Dbxref=GeneID:72551520;Name=OPG125;gbkey=Gene;gene=OPG125;gene_biotype=protein_coding;locus_tag=NBT03_gp104;old_locus_tag=MPXV-M5312_HM12_Rivers-108 +NC_063383.1 RefSeq CDS 105999 107654 . - 0 ID=cds-YP_010377107.1;Parent=gene-NBT03_gp104;Dbxref=GenBank:YP_010377107.1,GeneID:72551520;Name=OPG125;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp110%3B protein needed for the formation of immature IMV surface membrane%3B Trimeric virion coat protein (rifampicin res)%3B similar to VACV-WR E13L and VACV-Cop D13L;gbkey=CDS;gene=OPG125;locus_tag=NBT03_gp104;product=Rifampicin resistance protein;protein_id=YP_010377107.1 +NC_063383.1 RefSeq gene 107678 108130 . - . ID=gene-NBT03_gp105;Dbxref=GeneID:72551521;Name=OPG126;gbkey=Gene;gene=OPG126;gene_biotype=protein_coding;locus_tag=NBT03_gp105;old_locus_tag=MPXV-M5312_HM12_Rivers-109 +NC_063383.1 RefSeq CDS 107678 108130 . - 0 ID=cds-YP_010377108.1;Parent=gene-NBT03_gp105;Dbxref=GenBank:YP_010377108.1,GeneID:72551521;Name=OPG126;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp111%3B late gene transcription factor%2C VLTF-2%3B similar to VACV-WR A1L and VACV-Cop A1L;gbkey=CDS;gene=OPG126;locus_tag=NBT03_gp105;product=Late transcription factor VLTF-2 (2);protein_id=YP_010377108.1 +NC_063383.1 RefSeq gene 108151 108825 . - . ID=gene-NBT03_gp106;Dbxref=GeneID:72551522;Name=OPG127;gbkey=Gene;gene=OPG127;gene_biotype=protein_coding;locus_tag=NBT03_gp106;old_locus_tag=MPXV-M5312_HM12_Rivers-110 +NC_063383.1 RefSeq CDS 108151 108825 . - 0 ID=cds-YP_010377109.1;Parent=gene-NBT03_gp106;Dbxref=GenBank:YP_010377109.1,GeneID:72551522;Name=OPG127;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp112%3B late gene transcription factor%2C VLTF-3%3B zinc binding%3B similar to VACV-WR A2L and VACV-Cop A2L;gbkey=CDS;gene=OPG127;locus_tag=NBT03_gp106;product=Late transcription factor VLTF-3 (1);protein_id=YP_010377109.1 +NC_063383.1 RefSeq gene 108822 109055 . - . ID=gene-NBT03_gp107;Dbxref=GeneID:72551523;Name=OPG128;gbkey=Gene;gene=OPG128;gene_biotype=protein_coding;locus_tag=NBT03_gp107;old_locus_tag=MPXV-M5312_HM12_Rivers-111 +NC_063383.1 RefSeq CDS 108822 109055 . - 0 ID=cds-YP_010377110.1;Parent=gene-NBT03_gp107;Dbxref=GenBank:YP_010377110.1,GeneID:72551523;Name=OPG128;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp113%3B S-S bond formation pathway protein%3B similar to VACV-WR A3L and VACV-Cop A2.5L;gbkey=CDS;gene=OPG128;locus_tag=NBT03_gp107;product=S-S bond formation pathway protein;protein_id=YP_010377110.1 +NC_063383.1 RefSeq gene 109070 111004 . - . ID=gene-NBT03_gp108;Dbxref=GeneID:72551524;Name=OPG129;gbkey=Gene;gene=OPG129;gene_biotype=protein_coding;locus_tag=NBT03_gp108;old_locus_tag=MPXV-M5312_HM12_Rivers-112 +NC_063383.1 RefSeq CDS 109070 111004 . - 0 ID=cds-YP_010377111.1;Parent=gene-NBT03_gp108;Dbxref=GenBank:YP_010377111.1,GeneID:72551524;Name=OPG129;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp114%3B major virion core protein p4b%3B P4b precursor%3B similar to VACV-WR A4L and VACV-Cop A3L;gbkey=CDS;gene=OPG129;locus_tag=NBT03_gp108;product=Virion core protein P4b;protein_id=YP_010377111.1 +NC_063383.1 RefSeq gene 111057 111902 . - . ID=gene-NBT03_gp109;Dbxref=GeneID:72551525;Name=OPG130;gbkey=Gene;gene=OPG130;gene_biotype=protein_coding;locus_tag=NBT03_gp109;old_locus_tag=MPXV-M5312_HM12_Rivers-113 +NC_063383.1 RefSeq CDS 111057 111902 . - 0 ID=cds-YP_010377112.1;Parent=gene-NBT03_gp109;Dbxref=GenBank:YP_010377112.1,GeneID:72551525;Name=OPG130;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp115%3B 39 kDa immunodominant virion core protein needed for the progression of IV to infectious IMV%3B 39kDa virion core protein%3B similar to VACV-WR A5L and VACV-Cop A4L;gbkey=CDS;gene=OPG130;locus_tag=NBT03_gp109;product=A5L protein-like;protein_id=YP_010377112.1 +NC_063383.1 RefSeq gene 111940 112425 . + . ID=gene-NBT03_gp110;Dbxref=GeneID:72551526;Name=OPG131;gbkey=Gene;gene=OPG131;gene_biotype=protein_coding;locus_tag=NBT03_gp110;old_locus_tag=MPXV-M5312_HM12_Rivers-114 +NC_063383.1 RefSeq CDS 111940 112425 . + 0 ID=cds-YP_010377113.1;Parent=gene-NBT03_gp110;Dbxref=GenBank:YP_010377113.1,GeneID:72551526;Name=OPG131;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp116%3B precursor of RNA polymerase 22 kDa and 21 kDa%3B RNA polymerase subunit (RPO19)%3B similar to VACV-WR A6R and VACV-Cop A5R;gbkey=CDS;gene=OPG131;locus_tag=NBT03_gp110;product=DNA-directed RNA polymerase 19 kDa subunit;protein_id=YP_010377113.1 +NC_063383.1 RefSeq gene 112422 113540 . - . ID=gene-NBT03_gp111;Dbxref=GeneID:72551527;Name=OPG132;gbkey=Gene;gene=OPG132;gene_biotype=protein_coding;locus_tag=NBT03_gp111;old_locus_tag=MPXV-M5312_HM12_Rivers-115 +NC_063383.1 RefSeq CDS 112422 113540 . - 0 ID=cds-YP_010377114.1;Parent=gene-NBT03_gp111;Dbxref=GenBank:YP_010377114.1,GeneID:72551527;Name=OPG132;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp117%3B Viral membrane assembly proteins (VMAP)%2C core protein%3B similar to VACV-WR A7L and VACV-Cop A6L;gbkey=CDS;gene=OPG132;locus_tag=NBT03_gp111;product=Virion morphogenesis protein;protein_id=YP_010377114.1 +NC_063383.1 RefSeq gene 113564 115696 . - . ID=gene-NBT03_gp112;Dbxref=GeneID:72551528;Name=OPG133;gbkey=Gene;gene=OPG133;gene_biotype=protein_coding;locus_tag=NBT03_gp112;old_locus_tag=MPXV-M5312_HM12_Rivers-116 +NC_063383.1 RefSeq CDS 113564 115696 . - 0 ID=cds-YP_010377115.1;Parent=gene-NBT03_gp112;Dbxref=GenBank:YP_010377115.1,GeneID:72551528;Name=OPG133;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp118%3B early transcription factor%2C large subunit%2C VETF-L%3B needed for morphogenesis of the virion core%3B similar to VACV-WR A8L and VACV-Cop A7L;gbkey=CDS;gene=OPG133;locus_tag=NBT03_gp112;product=Early transcription factor 82 kDa subunit;protein_id=YP_010377115.1 +NC_063383.1 RefSeq gene 115750 116628 . + . ID=gene-NBT03_gp113;Dbxref=GeneID:72551529;Name=OPG134;gbkey=Gene;gene=OPG134;gene_biotype=protein_coding;locus_tag=NBT03_gp113;old_locus_tag=MPXV-M5312_HM12_Rivers-117 +NC_063383.1 RefSeq CDS 115750 116628 . + 0 ID=cds-YP_010377116.1;Parent=gene-NBT03_gp113;Dbxref=GenBank:YP_010377116.1,GeneID:72551529;Name=OPG134;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp119%3B intermediate transcription factor%2C VITF-3 34kda subunit%2C 34 kDa%3B similar to VACV-WR A9R and VACV-Cop A8R;gbkey=CDS;gene=OPG134;locus_tag=NBT03_gp113;product=Intermediate transcription factor VITF-3 (1);protein_id=YP_010377116.1 +NC_063383.1 RefSeq gene 116609 116911 . - . ID=gene-NBT03_gp114;Dbxref=GeneID:72551530;Name=OPG135;gbkey=Gene;gene=OPG135;gene_biotype=protein_coding;locus_tag=NBT03_gp114;old_locus_tag=MPXV-M5312_HM12_Rivers-118 +NC_063383.1 RefSeq CDS 116609 116911 . - 0 ID=cds-YP_010377117.1;Parent=gene-NBT03_gp114;Dbxref=GenBank:YP_010377117.1,GeneID:72551530;Name=OPG135;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp120%3B Viral membrane associated%2C early morphogenesis protein%3B similar to VACV-WR A10L and VACV-Cop A9L;gbkey=CDS;gene=OPG135;locus_tag=NBT03_gp114;product=IMV membrane protein A9;protein_id=YP_010377117.1 +NC_063383.1 RefSeq gene 116912 119587 . - . ID=gene-NBT03_gp115;Dbxref=GeneID:72551531;Name=OPG136;gbkey=Gene;gene=OPG136;gene_biotype=protein_coding;locus_tag=NBT03_gp115;old_locus_tag=MPXV-M5312_HM12_Rivers-119 +NC_063383.1 RefSeq CDS 116912 119587 . - 0 ID=cds-YP_010377118.1;Parent=gene-NBT03_gp115;Dbxref=GenBank:YP_010377118.1,GeneID:72551531;Name=OPG136;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp121%3B major virion core protein p4a%3B P4a precursor%3B similar to VACV-WR A11L and VACV-Cop A10L;gbkey=CDS;gene=OPG136;locus_tag=NBT03_gp115;product=Virion core protein P4a;protein_id=YP_010377118.1 +NC_063383.1 RefSeq gene 119602 120558 . + . ID=gene-NBT03_gp116;Dbxref=GeneID:72551532;Name=OPG137;gbkey=Gene;gene=OPG137;gene_biotype=protein_coding;locus_tag=NBT03_gp116;old_locus_tag=MPXV-M5312_HM12_Rivers-120 +NC_063383.1 RefSeq CDS 119602 120558 . + 0 ID=cds-YP_010377119.1;Parent=gene-NBT03_gp116;Dbxref=GenBank:YP_010377119.1,GeneID:72551532;Name=OPG137;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp122%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR A12R and VACV-Cop A11R;gbkey=CDS;gene=OPG137;locus_tag=NBT03_gp116;product=Viral membrane formation protein;protein_id=YP_010377119.1 +NC_063383.1 RefSeq gene 120560 121132 . - . ID=gene-NBT03_gp117;Dbxref=GeneID:72551533;Name=OPG138;gbkey=Gene;gene=OPG138;gene_biotype=protein_coding;locus_tag=NBT03_gp117;old_locus_tag=MPXV-M5312_HM12_Rivers-121 +NC_063383.1 RefSeq CDS 120560 121132 . - 0 ID=cds-YP_010377120.1;Parent=gene-NBT03_gp117;Dbxref=GenBank:YP_010377120.1,GeneID:72551533;Name=OPG138;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp123%3B Virion core and cleavage processing protein%3B similar to VACV-WR A13L and VACV-Cop A12L;gbkey=CDS;gene=OPG138;locus_tag=NBT03_gp117;product=A12 protein;protein_id=YP_010377120.1 +NC_063383.1 RefSeq gene 121156 121368 . - . ID=gene-NBT03_gp118;Dbxref=GeneID:72551534;Name=OPG139;gbkey=Gene;gene=OPG139;gene_biotype=protein_coding;locus_tag=NBT03_gp118;old_locus_tag=MPXV-M5312_HM12_Rivers-122 +NC_063383.1 RefSeq CDS 121156 121368 . - 0 ID=cds-YP_010377121.1;Parent=gene-NBT03_gp118;Dbxref=GenBank:YP_010377121.1,GeneID:72551534;Name=OPG139;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp124%3B IMV inner and outer membrane protein%3B virion maturation%3B similar to VACV-WR A14L and VACV-Cop A13L;gbkey=CDS;gene=OPG139;locus_tag=NBT03_gp118;product=IMV membrane protein A13L;protein_id=YP_010377121.1 +NC_063383.1 RefSeq gene 121474 121746 . - . ID=gene-NBT03_gp119;Dbxref=GeneID:72551535;Name=OPG140;gbkey=Gene;gene=OPG140;gene_biotype=protein_coding;locus_tag=NBT03_gp119;old_locus_tag=MPXV-M5312_HM12_Rivers-123 +NC_063383.1 RefSeq CDS 121474 121746 . - 0 ID=cds-YP_010377122.1;Parent=gene-NBT03_gp119;Dbxref=GenBank:YP_010377122.1,GeneID:72551535;Name=OPG140;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp125%3B IMV inner membrane protein%3B Essential IMV membrane protein%3B similar to VACV-WR A15L and VACV-Cop A14L;gbkey=CDS;gene=OPG140;locus_tag=NBT03_gp119;product=IMV membrane protein A14;protein_id=YP_010377122.1 +NC_063383.1 RefSeq gene 121763 121924 . - . ID=gene-NBT03_gp120;Dbxref=GeneID:72551536;Name=OPG141;gbkey=Gene;gene=OPG141;gene_biotype=protein_coding;locus_tag=NBT03_gp120;old_locus_tag=MPXV-M5312_HM12_Rivers-124 +NC_063383.1 RefSeq CDS 121763 121924 . - 0 ID=cds-YP_010377123.1;Parent=gene-NBT03_gp120;Dbxref=GenBank:YP_010377123.1,GeneID:72551536;Name=OPG141;Note=Taxonomic breadth: chordopoxvirinae%3B Non-essential IMV membrane protein%3B similar to VACV-WR A15.5L and VACV-Cop A14.5L;gbkey=CDS;gene=OPG141;locus_tag=NBT03_gp120;product=DUF1029 domain protein;protein_id=YP_010377123.1 +NC_063383.1 RefSeq gene 121914 122198 . - . ID=gene-NBT03_gp121;Dbxref=GeneID:72551537;Name=OPG142;gbkey=Gene;gene=OPG142;gene_biotype=protein_coding;locus_tag=NBT03_gp121;old_locus_tag=MPXV-M5312_HM12_Rivers-125 +NC_063383.1 RefSeq CDS 121914 122198 . - 0 ID=cds-YP_010377124.1;Parent=gene-NBT03_gp121;Dbxref=GenBank:YP_010377124.1,GeneID:72551537;Name=OPG142;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp126%3B Core protein%3B similar to VACV-WR A16L and VACV-Cop A15L;gbkey=CDS;gene=OPG142;locus_tag=NBT03_gp121;product=Core protein A15;protein_id=YP_010377124.1 +NC_063383.1 RefSeq gene 122182 123315 . - . ID=gene-NBT03_gp122;Dbxref=GeneID:72551538;Name=OPG143;gbkey=Gene;gene=OPG143;gene_biotype=protein_coding;locus_tag=NBT03_gp122;old_locus_tag=MPXV-M5312_HM12_Rivers-126 +NC_063383.1 RefSeq CDS 122182 123315 . - 0 ID=cds-YP_010377125.1;Parent=gene-NBT03_gp122;Dbxref=GenBank:YP_010377125.1,GeneID:72551538;Name=OPG143;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp127%3B soluble myristylated protein%3B essential for entry/fusion%3B similar to VACV-WR A17L and VACV-Cop A16L;gbkey=CDS;gene=OPG143;locus_tag=NBT03_gp122;product=Myristylated protein;protein_id=YP_010377125.1 +NC_063383.1 RefSeq gene 123318 123932 . - . ID=gene-NBT03_gp123;Dbxref=GeneID:72551539;Name=OPG144;gbkey=Gene;gene=OPG144;gene_biotype=protein_coding;locus_tag=NBT03_gp123;old_locus_tag=MPXV-M5312_HM12_Rivers-127 +NC_063383.1 RefSeq CDS 123318 123932 . - 0 ID=cds-YP_010377126.1;Parent=gene-NBT03_gp123;Dbxref=GenBank:YP_010377126.1,GeneID:72551539;Name=OPG144;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp128%3B IMV surface membrane protein%3B early function in virion morphgenesis%3B similar to VACV-WR A18L and VACV-Cop A17L;gbkey=CDS;gene=OPG144;locus_tag=NBT03_gp123;product=IMV membrane protein P21;protein_id=YP_010377126.1 +NC_063383.1 RefSeq gene 123947 125425 . + . ID=gene-NBT03_gp124;Dbxref=GeneID:72551540;Name=OPG145;gbkey=Gene;gene=OPG145;gene_biotype=protein_coding;locus_tag=NBT03_gp124;old_locus_tag=MPXV-M5312_HM12_Rivers-128 +NC_063383.1 RefSeq CDS 123947 125425 . + 0 ID=cds-YP_010377127.1;Parent=gene-NBT03_gp124;Dbxref=GenBank:YP_010377127.1,GeneID:72551540;Name=OPG145;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp129%3B virion core associated DNA helicase%3B post-replicative negative transcription elongation factor%3B transcript release factor%3B similar to VACV-WR A19R and VACV-Cop A18R;gbkey=CDS;gene=OPG145;locus_tag=NBT03_gp124;product=DNA helicase;protein_id=YP_010377127.1 +NC_063383.1 RefSeq gene 125406 125639 . - . ID=gene-NBT03_gp125;Dbxref=GeneID:72551541;Name=OPG146;gbkey=Gene;gene=OPG146;gene_biotype=protein_coding;locus_tag=NBT03_gp125;old_locus_tag=MPXV-M5312_HM12_Rivers-129 +NC_063383.1 RefSeq CDS 125406 125639 . - 0 ID=cds-YP_010377128.1;Parent=gene-NBT03_gp125;Dbxref=GenBank:YP_010377128.1,GeneID:72551541;Name=OPG146;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp130%3B Zinc finger-like protein%3B similar to VACV-WR A20L and VACV-Cop A19L;gbkey=CDS;gene=OPG146;locus_tag=NBT03_gp125;product=Zinc finger-like protein (1);protein_id=YP_010377128.1 +NC_063383.1 RefSeq gene 125640 125987 . - . ID=gene-NBT03_gp126;Dbxref=GeneID:72551542;Name=OPG147;gbkey=Gene;gene=OPG147;gene_biotype=protein_coding;locus_tag=NBT03_gp126;old_locus_tag=MPXV-M5312_HM12_Rivers-130 +NC_063383.1 RefSeq CDS 125640 125987 . - 0 ID=cds-YP_010377129.1;Parent=gene-NBT03_gp126;Dbxref=GenBank:YP_010377129.1,GeneID:72551542;Name=OPG147;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp131%3B IMV membrane protein%2C entry/fusion complex component%3B similar to VACV-WR A21L and VACV-Cop A21L;gbkey=CDS;gene=OPG147;locus_tag=NBT03_gp126;product=IMV membrane protein A21;protein_id=YP_010377129.1 +NC_063383.1 RefSeq gene 125986 127266 . + . ID=gene-NBT03_gp127;Dbxref=GeneID:72551543;Name=OPG148;gbkey=Gene;gene=OPG148;gene_biotype=protein_coding;locus_tag=NBT03_gp127;old_locus_tag=MPXV-M5312_HM12_Rivers-131 +NC_063383.1 RefSeq CDS 125986 127266 . + 0 ID=cds-YP_010377130.1;Parent=gene-NBT03_gp127;Dbxref=GenBank:YP_010377130.1,GeneID:72551543;Name=OPG148;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp132%3B processivity factor for the viral DNA polymerase%2C VPF%3B similar to VACV-WR A22R and VACV-Cop A20R;gbkey=CDS;gene=OPG148;locus_tag=NBT03_gp127;product=DNA polymerase processivity factor;protein_id=YP_010377130.1 +NC_063383.1 RefSeq gene 127196 127759 . + . ID=gene-NBT03_gp128;Dbxref=GeneID:72551544;Name=OPG149;gbkey=Gene;gene=OPG149;gene_biotype=protein_coding;locus_tag=NBT03_gp128;old_locus_tag=MPXV-M5312_HM12_Rivers-132 +NC_063383.1 RefSeq CDS 127196 127759 . + 0 ID=cds-YP_010377131.1;Parent=gene-NBT03_gp128;Dbxref=GenBank:YP_010377131.1,GeneID:72551544;Name=OPG149;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp133%3B Holliday junction resolvase%3B similar to VACV-WR A23R and VACV-Cop A22R;gbkey=CDS;gene=OPG149;locus_tag=NBT03_gp128;product=Holliday junction resolvase;protein_id=YP_010377131.1 +NC_063383.1 RefSeq gene 127779 128927 . + . ID=gene-NBT03_gp129;Dbxref=GeneID:72551545;Name=OPG150;gbkey=Gene;gene=OPG150;gene_biotype=protein_coding;locus_tag=NBT03_gp129;old_locus_tag=MPXV-M5312_HM12_Rivers-133 +NC_063383.1 RefSeq CDS 127779 128927 . + 0 ID=cds-YP_010377132.1;Parent=gene-NBT03_gp129;Dbxref=GenBank:YP_010377132.1,GeneID:72551545;Name=OPG150;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp134%3B intermediate transcription factor%2C VITF-3%2C 45 kDa subunit%3B similar to VACV-WR A24R and VACV-Cop A23R;gbkey=CDS;gene=OPG150;locus_tag=NBT03_gp129;product=Intermediate transcription factor VITF-3 (2);protein_id=YP_010377132.1 +NC_063383.1 RefSeq gene 128924 132418 . + . ID=gene-NBT03_gp130;Dbxref=GeneID:72551546;Name=OPG151;gbkey=Gene;gene=OPG151;gene_biotype=protein_coding;locus_tag=NBT03_gp130;old_locus_tag=MPXV-M5312_HM12_Rivers-134 +NC_063383.1 RefSeq CDS 128924 132418 . + 0 ID=cds-YP_010377133.1;Parent=gene-NBT03_gp130;Dbxref=GenBank:YP_010377133.1,GeneID:72551546;Name=OPG151;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp135%3B RNA polymerase%2C 132 kDa subunit (RPO132)%3B similar to VACV-WR A25R and VACV-Cop A24R;gbkey=CDS;gene=OPG151;locus_tag=NBT03_gp130;product=DNA-dependent RNA polymerase subunit rpo132;protein_id=YP_010377133.1 +NC_063383.1 RefSeq sequence_feature 132396 136092 . - . ID=id-NC_063383.1:132396..136092;exon_number=OPG152;gbkey=misc_feature;number=OPG152 +NC_063383.1 RefSeq gene 136138 137667 . - . ID=gene-NBT03_gp131;Dbxref=GeneID:72551547;Name=OPG153;gbkey=Gene;gene=OPG153;gene_biotype=protein_coding;locus_tag=NBT03_gp131;old_locus_tag=MPXV-M5312_HM12_Rivers-137 +NC_063383.1 RefSeq CDS 136138 137667 . - 0 ID=cds-YP_010377134.1;Parent=gene-NBT03_gp131;Dbxref=GenBank:YP_010377134.1,GeneID:72551547;Name=OPG153;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp138%3B major component of IMV surface tubules%3B A-type inclusion protein%3B P4c precursor%3B similar to VACV-WR A28L and VACV-Cop A26L;gbkey=CDS;gene=OPG153;locus_tag=NBT03_gp131;product=Orthopoxvirus A26L/A30L protein;protein_id=YP_010377134.1 +NC_063383.1 RefSeq gene 137718 138050 . - . ID=gene-NBT03_gp132;Dbxref=GeneID:72551548;Name=OPG154;gbkey=Gene;gene=OPG154;gene_biotype=protein_coding;locus_tag=NBT03_gp132;old_locus_tag=MPXV-M5312_HM12_Rivers-138 +NC_063383.1 RefSeq CDS 137718 138050 . - 0 ID=cds-YP_010377135.1;Parent=gene-NBT03_gp132;Dbxref=GenBank:YP_010377135.1,GeneID:72551548;Name=OPG154;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp139%3B IMV surface membrane 14 kDa fusion protein%3B binding to cell surface heparan%3B similar to VACV-WR A29L and VACV-Cop A27L;gbkey=CDS;gene=OPG154;locus_tag=NBT03_gp132;product=IMV surface fusion protein;protein_id=YP_010377135.1 +NC_063383.1 RefSeq gene 138051 138491 . - . ID=gene-NBT03_gp133;Dbxref=GeneID:72551549;Name=OPG155;gbkey=Gene;gene=OPG155;gene_biotype=protein_coding;locus_tag=NBT03_gp133;old_locus_tag=MPXV-M5312_HM12_Rivers-139 +NC_063383.1 RefSeq CDS 138051 138491 . - 0 ID=cds-YP_010377136.1;Parent=gene-NBT03_gp133;Dbxref=GenBank:YP_010377136.1,GeneID:72551549;Name=OPG155;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp140%3B IMV MP/Virus entry%3B similar to VACV-WR A30L and VACV-Cop A28L;gbkey=CDS;gene=OPG155;locus_tag=NBT03_gp133;product=Envelope protein A28 homolog;protein_id=YP_010377136.1 +NC_063383.1 RefSeq gene 138492 139409 . - . ID=gene-NBT03_gp134;Dbxref=GeneID:72551550;Name=OPG156;gbkey=Gene;gene=OPG156;gene_biotype=protein_coding;locus_tag=NBT03_gp134;old_locus_tag=MPXV-M5312_HM12_Rivers-140 +NC_063383.1 RefSeq CDS 138492 139409 . - 0 ID=cds-YP_010377137.1;Parent=gene-NBT03_gp134;Dbxref=GenBank:YP_010377137.1,GeneID:72551550;Name=OPG156;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp141%3B RNA polymerase%2C 35 kDa subunit (RPO35)%3B similar to VACV-WR A31L and VACV-Cop A29L;gbkey=CDS;gene=OPG156;locus_tag=NBT03_gp134;product=DNA-directed RNA polymerase 35 kDa subunit;protein_id=YP_010377137.1 +NC_063383.1 RefSeq gene 139372 139608 . - . ID=gene-NBT03_gp135;Dbxref=GeneID:72551551;Name=OPG157;gbkey=Gene;gene=OPG157;gene_biotype=protein_coding;locus_tag=NBT03_gp135;old_locus_tag=MPXV-M5312_HM12_Rivers-141 +NC_063383.1 RefSeq CDS 139372 139608 . - 0 ID=cds-YP_010377138.1;Parent=gene-NBT03_gp135;Dbxref=GenBank:YP_010377138.1,GeneID:72551551;Name=OPG157;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp142%3B IMV protein%3B similar to VACV-WR A32L and VACV-Cop A30L;gbkey=CDS;gene=OPG157;locus_tag=NBT03_gp135;product=IMV membrane protein A30;protein_id=YP_010377138.1 +NC_063383.1 RefSeq gene 139641 139769 . - . ID=gene-NBT03_gp136;Dbxref=GeneID:72551552;Name=OPG158;gbkey=Gene;gene=OPG158;gene_biotype=protein_coding;locus_tag=NBT03_gp136;old_locus_tag=MPXV-M5312_HM12_Rivers-142 +NC_063383.1 RefSeq CDS 139641 139769 . - 0 ID=cds-YP_010377139.1;Parent=gene-NBT03_gp136;Dbxref=GenBank:YP_010377139.1,GeneID:72551552;Name=OPG158;Note=Viral membrane assembly proteins (VMAP)%3B similar to VACV-Cop A30.5L;gbkey=CDS;gene=OPG158;locus_tag=NBT03_gp136;product=A32.5L;protein_id=YP_010377139.1 +NC_063383.1 RefSeq gene 139768 140205 . + . ID=gene-NBT03_gp137;Dbxref=GeneID:72551553;Name=OPG159;gbkey=Gene;gene=OPG159;gene_biotype=protein_coding;locus_tag=NBT03_gp137;old_locus_tag=MPXV-M5312_HM12_Rivers-143 +NC_063383.1 RefSeq CDS 139768 140205 . + 0 ID=cds-YP_010377140.1;Parent=gene-NBT03_gp137;Dbxref=GenBank:YP_010377140.1,GeneID:72551553;Name=OPG159;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp143%3B Hypothetical protein%3B similar to VACV-WR A33R and VACV-Cop A31R;gbkey=CDS;gene=OPG159;locus_tag=NBT03_gp137;product=CPXV166 protein;protein_id=YP_010377140.1 +NC_063383.1 RefSeq gene 140172 141074 . - . ID=gene-NBT03_gp138;Dbxref=GeneID:72551554;Name=OPG160;gbkey=Gene;gene=OPG160;gene_biotype=protein_coding;locus_tag=NBT03_gp138;old_locus_tag=MPXV-M5312_HM12_Rivers-144 +NC_063383.1 RefSeq CDS 140172 141074 . - 0 ID=cds-YP_010377141.1;Parent=gene-NBT03_gp138;Dbxref=GenBank:YP_010377141.1,GeneID:72551554;Name=OPG160;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp144%3B DNA packaging into virion%3B NTP-binding motif A%3B ATPase/DNA packaging protein%3B similar to VACV-WR A34L and VACV-Cop A32L;gbkey=CDS;gene=OPG160;locus_tag=NBT03_gp138;product=ATPase A32;protein_id=YP_010377141.1 +NC_063383.1 RefSeq gene 141102 141647 . + . ID=gene-NBT03_gp139;Dbxref=GeneID:72551555;Name=OPG161;gbkey=Gene;gene=OPG161;gene_biotype=protein_coding;locus_tag=NBT03_gp139;old_locus_tag=MPXV-M5312_HM12_Rivers-145 +NC_063383.1 RefSeq CDS 141102 141647 . + 0 ID=cds-YP_010377142.1;Parent=gene-NBT03_gp139;Dbxref=GenBank:YP_010377142.1,GeneID:72551555;Name=OPG161;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp145%3B EEV envelope glycoprotein%2C needed for formation of actin-containing microvilli and cell-to-cell spread of virion%3B interacts with VAC A36R%3B EEV membrane phosphoglycoprotein%2C C-type lectin-like domain%3B similar to VACV-WR A35R and VACV-Cop A33R;gbkey=CDS;gene=OPG161;locus_tag=NBT03_gp139;product=EEV glycoprotein (1);protein_id=YP_010377142.1 +NC_063383.1 RefSeq gene 141652 142158 . + . ID=gene-NBT03_gp140;Dbxref=GeneID:72551556;Name=OPG162;gbkey=Gene;gene=OPG162;gene_biotype=protein_coding;locus_tag=NBT03_gp140;old_locus_tag=MPXV-M5312_HM12_Rivers-146 +NC_063383.1 RefSeq CDS 141652 142158 . + 0 ID=cds-YP_010377143.1;Parent=gene-NBT03_gp140;Dbxref=GenBank:YP_010377143.1,GeneID:72551556;Name=OPG162;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp146%3B EEV envelope glycoprotein%2C lectin-like%3B required for infectivity of EEV%2C formation of actin-containing microvilli%2C and cell-to-cell spread of virion%3B C-type lectin-like IEV/EEV glycoprotein%3B similar to VACV-WR A36R and VACV-Cop A34R;gbkey=CDS;gene=OPG162;locus_tag=NBT03_gp140;product=EEV glycoprotein (2);protein_id=YP_010377143.1 +NC_063383.1 RefSeq gene 142202 142732 . + . ID=gene-NBT03_gp141;Dbxref=GeneID:72551557;Name=OPG163;gbkey=Gene;gene=OPG163;gene_biotype=protein_coding;locus_tag=NBT03_gp141;old_locus_tag=MPXV-M5312_HM12_Rivers-147 +NC_063383.1 RefSeq CDS 142202 142732 . + 0 ID=cds-YP_010377144.1;Parent=gene-NBT03_gp141;Dbxref=GenBank:YP_010377144.1,GeneID:72551557;Name=OPG163;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp147%3B MHC class II antigen presentation inhibitor%3B similar to VACV-WR A37R and VACV-Cop A35R;gbkey=CDS;gene=OPG163;locus_tag=NBT03_gp141;product=MHC class II antigen presentation inhibitor;protein_id=YP_010377144.1 +NC_063383.1 RefSeq gene 142778 143464 . + . ID=gene-NBT03_gp142;Dbxref=GeneID:72551558;Name=OPG164;gbkey=Gene;gene=OPG164;gene_biotype=protein_coding;locus_tag=NBT03_gp142;old_locus_tag=MPXV-M5312_HM12_Rivers-148 +NC_063383.1 RefSeq CDS 142778 143464 . + 0 ID=cds-YP_010377145.1;Parent=gene-NBT03_gp142;Dbxref=GenBank:YP_010377145.1,GeneID:72551558;Name=OPG164;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp148%3B IEV but not CEV envelope protein%3B plays critical role for actin tail formation%3B interacts with VAC A33R and A34R%3B IEV transmembrane phosphoprotein%3B similar to VACV-WR A38R and VACV-Cop A36R;gbkey=CDS;gene=OPG164;locus_tag=NBT03_gp142;product=IEV transmembrane phosphoprotein;protein_id=YP_010377145.1 +NC_063383.1 RefSeq gene 143516 144322 . + . ID=gene-NBT03_gp143;Dbxref=GeneID:72551559;Name=OPG165;gbkey=Gene;gene=OPG165;gene_biotype=protein_coding;locus_tag=NBT03_gp143;old_locus_tag=MPXV-M5312_HM12_Rivers-149 +NC_063383.1 RefSeq CDS 143516 144322 . + 0 ID=cds-YP_010377146.1;Parent=gene-NBT03_gp143;Dbxref=GenBank:YP_010377146.1,GeneID:72551559;Name=OPG165;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp149%3B Hypothetical protein%3B similar to VACV-WR A39R and VACV-Cop A37R;gbkey=CDS;gene=OPG165;locus_tag=NBT03_gp143;product=CPXV173 protein;protein_id=YP_010377146.1 +NC_063383.1 RefSeq gene 144398 144577 . + . ID=gene-NBT03_gp144;Dbxref=GeneID:72551560;Name=OPG166;gbkey=Gene;gene=OPG166;gene_biotype=protein_coding;locus_tag=NBT03_gp144 +NC_063383.1 RefSeq CDS 144398 144577 . + 0 ID=cds-YP_010415322.1;Parent=gene-NBT03_gp144;Dbxref=GenBank:YP_010415322.1,GeneID:72551560;Name=OPG166;Note=Hypothetical protein%3B according to YP_233043.1%2C this VACV-WR protein was purified by sucrose gradient centrifugation%3B similar to VACWR161 and VARGAR-A43R;gbkey=CDS;gene=OPG166;locus_tag=NBT03_gp144;product=hypothetical protein;protein_id=YP_010415322.1 +NC_063383.1 RefSeq gene 144574 145407 . - . ID=gene-NBT03_gp145;Dbxref=GeneID:72551561;Name=OPG167;gbkey=Gene;gene=OPG167;gene_biotype=protein_coding;locus_tag=NBT03_gp145;old_locus_tag=MPXV-M5312_HM12_Rivers-150 +NC_063383.1 RefSeq CDS 144574 145407 . - 0 ID=cds-YP_010377147.1;Parent=gene-NBT03_gp145;Dbxref=GenBank:YP_010377147.1,GeneID:72551561;Name=OPG167;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp150%3B integral membrane glycoprotein%3B immunoglobulin-like%3B regulation of the influx of extracellular Ca2+%3B CD47-like%3B similar to VACV-WR A40L and VACV-Cop A38L;gbkey=CDS;gene=OPG167;locus_tag=NBT03_gp145;product=CD47-like protein;protein_id=YP_010377147.1 +NC_063383.1 RefSeq sequence_feature 145423 145856 . + . ID=id-NC_063383.1:145423..145856;exon_number=OPG168;gbkey=misc_feature;number=OPG168 +NC_063383.1 RefSeq sequence_feature 145857 146039 . + . ID=id-NC_063383.1:145857..146039;exon_number=OPG169;gbkey=misc_feature;number=OPG169 +NC_063383.1 RefSeq gene 146113 146778 . - . ID=gene-NBT03_gp146;Dbxref=GeneID:72551562;Name=OPG170;gbkey=Gene;gene=OPG170;gene_biotype=protein_coding;locus_tag=NBT03_gp146;old_locus_tag=MPXV-M5312_HM12_Rivers-151 +NC_063383.1 RefSeq CDS 146113 146778 . - 0 ID=cds-YP_010377148.1;Parent=gene-NBT03_gp146;Dbxref=GenBank:YP_010377148.1,GeneID:72551562;Name=OPG170;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp151%3B secreted protein reducing infiltration of inflammatory cells into the infected area%3B Chemokine binding protein%3B similar to VACV-WR A41L and VACV-Cop A41L;gbkey=CDS;gene=OPG170;locus_tag=NBT03_gp146;product=Chemokine binding protein;protein_id=YP_010377148.1 +NC_063383.1 RefSeq gene 146988 147389 . + . ID=gene-NBT03_gp147;Dbxref=GeneID:72551563;Name=OPG171;gbkey=Gene;gene=OPG171;gene_biotype=protein_coding;locus_tag=NBT03_gp147;old_locus_tag=MPXV-M5312_HM12_Rivers-152 +NC_063383.1 RefSeq CDS 146988 147389 . + 0 ID=cds-YP_010377149.1;Parent=gene-NBT03_gp147;Dbxref=GenBank:YP_010377149.1,GeneID:72551563;Name=OPG171;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp152%3B Profilin-like protein%2C ATI-localized%3B similar to VACV-WR A42R and VACV-Cop A42R;gbkey=CDS;gene=OPG171;locus_tag=NBT03_gp147;product=Profilin domain protein;protein_id=YP_010377149.1 +NC_063383.1 RefSeq gene 147427 148017 . + . ID=gene-NBT03_gp148;Dbxref=GeneID:72551564;Name=OPG172;gbkey=Gene;gene=OPG172;gene_biotype=protein_coding;locus_tag=NBT03_gp148;old_locus_tag=MPXV-M5312_HM12_Rivers-153 +NC_063383.1 RefSeq CDS 147427 148017 . + 0 ID=cds-YP_010377150.1;Parent=gene-NBT03_gp148;Dbxref=GenBank:YP_010377150.1,GeneID:72551564;Name=OPG172;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp153%3B Type I membrane glycoprotein%3B similar to VACV-WR A43R and VACV-Cop A43R;gbkey=CDS;gene=OPG172;locus_tag=NBT03_gp148;product=Type-I membrane glycoprotein;protein_id=YP_010377150.1 +NC_063383.1 RefSeq gene 148037 148261 . + . ID=gene-NBT03_gp149;Dbxref=GeneID:72551565;Name=OPG173;gbkey=Gene;gene=OPG173;gene_biotype=protein_coding;locus_tag=NBT03_gp149;old_locus_tag=MPXV-M5312_HM12_Rivers-154 +NC_063383.1 RefSeq CDS 148037 148261 . + 0 ID=cds-YP_010377151.1;Parent=gene-NBT03_gp149;Dbxref=GenBank:YP_010377151.1,GeneID:72551565;Name=OPG173;Note=Old product: MPXVgp154%3B Hypothetical protein%3B similar to VACV-WR A44R and VACV-Cop A43.5R;gbkey=CDS;gene=OPG173;locus_tag=NBT03_gp149;product=MPXVgp154;protein_id=YP_010377151.1 +NC_063383.1 RefSeq gene 148355 149395 . - . ID=gene-NBT03_gp150;Dbxref=GeneID:72551566;Name=OPG174;gbkey=Gene;gene=OPG174;gene_biotype=protein_coding;locus_tag=NBT03_gp150;old_locus_tag=MPXV-M5312_HM12_Rivers-155 +NC_063383.1 RefSeq CDS 148355 149395 . - 0 ID=cds-YP_010377152.1;Parent=gene-NBT03_gp150;Dbxref=GenBank:YP_010377152.1,GeneID:72551566;Name=OPG174;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp155%3B 3-b-Hydroxy-delta5-steroid dehydrogenase%3B 3 beta-hydroxysteroid dehydrogenase/delta 5->4 isomerase%3B similar to VACV-WR A45L and VACV-Cop A44L;gbkey=CDS;gene=OPG174;locus_tag=NBT03_gp150;product=Hydroxysteroid dehydrogenase;protein_id=YP_010377152.1 +NC_063383.1 RefSeq gene 149442 149819 . + . ID=gene-NBT03_gp151;Dbxref=GeneID:72551567;Name=OPG175;gbkey=Gene;gene=OPG175;gene_biotype=protein_coding;locus_tag=NBT03_gp151;old_locus_tag=MPXV-M5312_HM12_Rivers-156 +NC_063383.1 RefSeq CDS 149442 149819 . + 0 ID=cds-YP_010377153.1;Parent=gene-NBT03_gp151;Dbxref=GenBank:YP_010377153.1,GeneID:72551567;Name=OPG175;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp156%3B virion core protein%3B Inactive Cu-Zn superoxide dismutase-like virion protein%3B similar to VACV-WR A46R and VACV-Cop A45R;gbkey=CDS;gene=OPG175;locus_tag=NBT03_gp151;product=Copper/zinc superoxide dismutase;protein_id=YP_010377153.1 +NC_063383.1 RefSeq gene 149809 150531 . + . ID=gene-NBT03_gp152;Dbxref=GeneID:72551568;Name=OPG176;gbkey=Gene;gene=OPG176;gene_biotype=protein_coding;locus_tag=NBT03_gp152;old_locus_tag=MPXV-M5312_HM12_Rivers-157 +NC_063383.1 RefSeq CDS 149809 150531 . + 0 ID=cds-YP_010377154.1;Parent=gene-NBT03_gp152;Dbxref=GenBank:YP_010377154.1,GeneID:72551568;Name=OPG176;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp157%3B IL-1/TLR signaling inhibitor%3B similar to VACV-WR A47R and VACV-Cop A46R;gbkey=CDS;gene=OPG176;locus_tag=NBT03_gp152;product=Bcl-2-like protein;protein_id=YP_010377154.1 +NC_063383.1 RefSeq sequence_feature 150684 151407 . - . ID=id-NC_063383.1:150684..151407;exon_number=OPG177;gbkey=misc_feature;number=OPG177 +NC_063383.1 RefSeq gene 151509 152123 . + . ID=gene-NBT03_gp153;Dbxref=GeneID:72551569;Name=OPG178;gbkey=Gene;gene=OPG178;gene_biotype=protein_coding;locus_tag=NBT03_gp153;old_locus_tag=MPXV-M5312_HM12_Rivers-158 +NC_063383.1 RefSeq CDS 151509 152123 . + 0 ID=cds-YP_010377155.1;Parent=gene-NBT03_gp153;Dbxref=GenBank:YP_010377155.1,GeneID:72551569;Name=OPG178;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp159%3B thymidylate kinase%3B start of ORF is missing approx. 37 AA compared to CPXVs%3B similar to VACV-WR A49R and VACV-Cop A48R;gbkey=CDS;gene=OPG178;locus_tag=NBT03_gp153;product=Thymidylate kinase;protein_id=YP_010377155.1 +NC_063383.1 RefSeq sequence_feature 152172 152660 . + . ID=id-NC_063383.1:152172..152660;exon_number=OPG179;gbkey=misc_feature;number=OPG179 +NC_063383.1 RefSeq gene 152692 154371 . + . ID=gene-NBT03_gp154;Dbxref=GeneID:72551570;Name=OPG180;gbkey=Gene;gene=OPG180;gene_biotype=protein_coding;locus_tag=NBT03_gp154;old_locus_tag=MPXV-M5312_HM12_Rivers-159 +NC_063383.1 RefSeq CDS 152692 154371 . + 0 ID=cds-YP_010377156.1;Parent=gene-NBT03_gp154;Dbxref=GenBank:YP_010377156.1,GeneID:72551570;Name=OPG180;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp160%3B ATP-dependent DNA ligase%3B similar to VACV-WR A50R and VACV-Cop A50R;gbkey=CDS;gene=OPG180;locus_tag=NBT03_gp154;product=DNA ligase (2);protein_id=YP_010377156.1 +NC_063383.1 RefSeq gene 154412 155416 . + . ID=gene-NBT03_gp155;Dbxref=GeneID:72551571;Name=OPG181;gbkey=Gene;gene=OPG181;gene_biotype=protein_coding;locus_tag=NBT03_gp155;old_locus_tag=MPXV-M5312_HM12_Rivers-160 +NC_063383.1 RefSeq CDS 154412 155416 . + 0 ID=cds-YP_010377157.1;Parent=gene-NBT03_gp155;Dbxref=GenBank:YP_010377157.1,GeneID:72551571;Name=OPG181;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp161%3B Hypothetical protein%3B similar to VACV-WR A51R and VACV-Cop A51R;gbkey=CDS;gene=OPG181;locus_tag=NBT03_gp155;product=M137R;protein_id=YP_010377157.1 +NC_063383.1 RefSeq sequence_feature 155485 156037 . + . ID=id-NC_063383.1:155485..156037;exon_number=OPG182;gbkey=misc_feature;number=OPG182 +NC_063383.1 RefSeq sequence_feature 156355 156916 . + . ID=id-NC_063383.1:156355..156916;exon_number=OPG183;gbkey=misc_feature;number=OPG183 +NC_063383.1 RefSeq sequence_feature 157176 158867 . + . ID=id-NC_063383.1:157176..158867;exon_number=OPG184;gbkey=misc_feature;number=OPG184 +NC_063383.1 RefSeq gene 158917 159858 . + . ID=gene-NBT03_gp156;Dbxref=GeneID:72551572;Name=OPG185;gbkey=Gene;gene=OPG185;gene_biotype=protein_coding;locus_tag=NBT03_gp156;old_locus_tag=MPXV-M5312_HM12_Rivers-162 +NC_063383.1 RefSeq CDS 158917 159858 . + 0 ID=cds-YP_010377158.1;Parent=gene-NBT03_gp156;Dbxref=GenBank:YP_010377158.1,GeneID:72551572;Name=OPG185;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp163%3B EEV envelope and cell membrane glycoprotein hemagglutinin%3B inhibition of the ability of infected cells to fuse%3B interacts with VAC F13L%3B similar to VACV-WR B2R and VACV-Cop A56R;gbkey=CDS;gene=OPG185;locus_tag=NBT03_gp156;product=Hemagglutinin;protein_id=YP_010377158.1 +NC_063383.1 RefSeq sequence_feature 159876 160470 . + . ID=id-NC_063383.1:159876..160470;exon_number=OPG186;gbkey=misc_feature;number=OPG186 +NC_063383.1 RefSeq gene 160622 161533 . + . ID=gene-NBT03_gp157;Dbxref=GeneID:72551573;Name=OPG187;gbkey=Gene;gene=OPG187;gene_biotype=protein_coding;locus_tag=NBT03_gp157;old_locus_tag=MPXV-M5312_HM12_Rivers-163 +NC_063383.1 RefSeq CDS 160622 161533 . + 0 ID=cds-YP_010377159.1;Parent=gene-NBT03_gp157;Dbxref=GenBank:YP_010377159.1,GeneID:72551573;Name=OPG187;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp164%3B serine%3B Ser/Thr Kinase%3B similar to VACV-WR B3R and VACV-Cop B1R;gbkey=CDS;gene=OPG187;locus_tag=NBT03_gp157;product=Ser/thr kinase;protein_id=YP_010377159.1 +NC_063383.1 RefSeq gene 161596 163107 . + . ID=gene-NBT03_gp158;Dbxref=GeneID:72551574;Name=OPG188;gbkey=Gene;gene=OPG188;gene_biotype=protein_coding;locus_tag=NBT03_gp158;old_locus_tag=MPXV-M5312_HM12_Rivers-164 +NC_063383.1 RefSeq CDS 161596 163107 . + 0 ID=cds-YP_010377160.1;Parent=gene-NBT03_gp158;Dbxref=GenBank:YP_010377160.1,GeneID:72551574;Name=OPG188;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp165%3B schlafen-like%3B similar to VACV-WR B4R and VACV-Cop B2R;gbkey=CDS;gene=OPG188;locus_tag=NBT03_gp158;product=Schlafen (1);protein_id=YP_010377160.1 +NC_063383.1 RefSeq gene 163333 165018 . + . ID=gene-NBT03_gp159;Dbxref=GeneID:72551575;Name=OPG189;gbkey=Gene;gene=OPG189;gene_biotype=protein_coding;locus_tag=NBT03_gp159;old_locus_tag=MPXV-M5312_HM12_Rivers-165 +NC_063383.1 RefSeq CDS 163333 165018 . + 0 ID=cds-YP_010377161.1;Parent=gene-NBT03_gp159;Dbxref=GenBank:YP_010377161.1,GeneID:72551575;Name=OPG189;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp166%3B ankyrin-like%3B similar to VACV-WR B5R and VACV-Cop B4R;gbkey=CDS;gene=OPG189;locus_tag=NBT03_gp159;product=Ankyrin repeat protein (25);protein_id=YP_010377161.1 +NC_063383.1 RefSeq gene 165122 166075 . + . ID=gene-NBT03_gp160;Dbxref=GeneID:72551576;Name=OPG190;gbkey=Gene;gene=OPG190;gene_biotype=protein_coding;locus_tag=NBT03_gp160;old_locus_tag=MPXV-M5312_HM12_Rivers-166 +NC_063383.1 RefSeq CDS 165122 166075 . + 0 ID=cds-YP_010377162.1;Parent=gene-NBT03_gp160;Dbxref=GenBank:YP_010377162.1,GeneID:72551576;Name=OPG190;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp167%3B palmitated 42 kDa glycoprotein located both on the membranes of infected cells and on EEV envelope%3B complement control protein-like%3B EEV type-1 membrane glycoprotein%2C protective antigen%3B similar to VACV-WR B6R and VACV-Cop B5R;gbkey=CDS;gene=OPG190;locus_tag=NBT03_gp160;product=EEV type-I membrane glycoprotein;protein_id=YP_010377162.1 +NC_063383.1 RefSeq gene 166161 166667 . + . ID=gene-NBT03_gp161;Dbxref=GeneID:72551577;Name=OPG191;gbkey=Gene;gene=OPG191;gene_biotype=protein_coding;locus_tag=NBT03_gp161;old_locus_tag=MPXV-M5312_HM12_Rivers-167 +NC_063383.1 RefSeq CDS 166161 166667 . + 0 ID=cds-YP_010377163.1;Parent=gene-NBT03_gp161;Dbxref=GenBank:YP_010377163.1,GeneID:72551577;Name=OPG191;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp168%3B Ankyrin-like protein%3B similar to VACV-WR B7R and VACV-Cop B6R;gbkey=CDS;gene=OPG191;locus_tag=NBT03_gp161;product=Ankyrin-like protein (46);protein_id=YP_010377163.1 +NC_063383.1 RefSeq gene 166731 167279 . + . ID=gene-NBT03_gp162;Dbxref=GeneID:72551578;Name=OPG192;gbkey=Gene;gene=OPG192;gene_biotype=protein_coding;locus_tag=NBT03_gp162;old_locus_tag=MPXV-M5312_HM12_Rivers-168 +NC_063383.1 RefSeq CDS 166731 167279 . + 0 ID=cds-YP_010377164.1;Parent=gene-NBT03_gp162;Dbxref=GenBank:YP_010377164.1,GeneID:72551578;Name=OPG192;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp169%3B Virulence%2C ER resident%3B similar to VACV-WR B8R and VACV-Cop B7R;gbkey=CDS;gene=OPG192;locus_tag=NBT03_gp162;product=Virulence protein;protein_id=YP_010377164.1 +NC_063383.1 RefSeq gene 167334 168137 . + . ID=gene-NBT03_gp163;Dbxref=GeneID:72551579;Name=OPG193;gbkey=Gene;gene=OPG193;gene_biotype=protein_coding;locus_tag=NBT03_gp163;old_locus_tag=MPXV-M5312_HM12_Rivers-169 +NC_063383.1 RefSeq CDS 167334 168137 . + 0 ID=cds-YP_010377165.1;Parent=gene-NBT03_gp163;Dbxref=GenBank:YP_010377165.1,GeneID:72551579;Name=OPG193;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp170%3B secreted IFN-g binding protein%3B Soluble IFN-g receptor-like protein%3B similar to VACV-WR B9R and VACV-Cop B8R;gbkey=CDS;gene=OPG193;locus_tag=NBT03_gp163;product=Soluble interferon-gamma receptor-like protein;protein_id=YP_010377165.1 +NC_063383.1 RefSeq gene 168230 168895 . + . ID=gene-NBT03_gp164;Dbxref=GeneID:72551580;Name=OPG195;gbkey=Gene;gene=OPG195;gene_biotype=protein_coding;locus_tag=NBT03_gp164;old_locus_tag=MPXV-M5312_HM12_Rivers-170 +NC_063383.1 RefSeq CDS 168230 168895 . + 0 ID=cds-YP_010377166.1;Parent=gene-NBT03_gp164;Dbxref=GenBank:YP_010377166.1,GeneID:72551580;Name=OPG195;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp171%3B shope fibroma virus T4 protein-like%3B ER-localized apoptosis regulator%3B similar to VACV-WR B10R and VACV-Cop B9R;gbkey=CDS;gene=OPG195;locus_tag=NBT03_gp164;product=Intracellular viral protein;protein_id=YP_010377166.1 +NC_063383.1 RefSeq sequence_feature 169001 169642 . + . ID=id-NC_063383.1:169001..169642;exon_number=OPG196;gbkey=misc_feature;number=OPG196 +NC_063383.1 RefSeq gene 169670 169972 . + . ID=gene-NBT03_gp165;Dbxref=GeneID:72551581;Name=OPG197;gbkey=Gene;gene=OPG197;gene_biotype=protein_coding;locus_tag=NBT03_gp165;old_locus_tag=MPXV-M5312_HM12_Rivers-171 +NC_063383.1 RefSeq CDS 169670 169972 . + 0 ID=cds-YP_010377167.1;Parent=gene-NBT03_gp165;Dbxref=GenBank:YP_010377167.1,GeneID:72551581;Name=OPG197;Note=Taxonomic breadth: chordopoxvirinae%3B Hypothetical protein%3B similar to VACV-Cop-B11R;gbkey=CDS;gene=OPG197;locus_tag=NBT03_gp165;product=CPXV205 protein;protein_id=YP_010377167.1 +NC_063383.1 RefSeq gene 170038 170886 . + . ID=gene-NBT03_gp166;Dbxref=GeneID:72551582;Name=OPG198;gbkey=Gene;gene=OPG198;gene_biotype=protein_coding;locus_tag=NBT03_gp166;old_locus_tag=MPXV-M5312_HM12_Rivers-172 +NC_063383.1 RefSeq CDS 170038 170886 . + 0 ID=cds-YP_010377168.1;Parent=gene-NBT03_gp166;Dbxref=GenBank:YP_010377168.1,GeneID:72551582;Name=OPG198;Note=Taxonomic breadth: poxviridae%3B protein kinase-like%3B similar to VACV-WR B11R and VACV-Cop B12R;gbkey=CDS;gene=OPG198;locus_tag=NBT03_gp166;product=Ser/thr kinase;protein_id=YP_010377168.1 +NC_063383.1 RefSeq gene 170988 172022 . + . ID=gene-NBT03_gp167;Dbxref=GeneID:72551583;Name=OPG199;gbkey=Gene;gene=OPG199;gene_biotype=protein_coding;locus_tag=NBT03_gp167;old_locus_tag=MPXV-M5312_HM12_Rivers-173 +NC_063383.1 RefSeq CDS 170988 172022 . + 0 ID=cds-YP_010377169.1;Parent=gene-NBT03_gp167;Dbxref=GenBank:YP_010377169.1,GeneID:72551583;Name=OPG199;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp173%3B serine protease inhibitor-like%2C SPI-2%3B inhibition of the IL-1b converting enzyme%3B apoptosis inhibition%3B Serpin 1%2C2%2C3%3B similar to VACV-WR B12R and VACV-Cop K2L;gbkey=CDS;gene=OPG199;locus_tag=NBT03_gp167;product=Serpin;protein_id=YP_010377169.1 +NC_063383.1 RefSeq gene 172150 172599 . + . ID=gene-NBT03_gp168;Dbxref=GeneID:72551584;Name=OPG200;gbkey=Gene;gene=OPG200;gene_biotype=protein_coding;locus_tag=NBT03_gp168;old_locus_tag=MPXV-M5312_HM12_Rivers-174 +NC_063383.1 RefSeq CDS 172150 172599 . + 0 ID=cds-YP_010377170.1;Parent=gene-NBT03_gp168;Dbxref=GenBank:YP_010377170.1,GeneID:72551584;Name=OPG200;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp174%3B Hypothetical protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR B13R and VACV-Cop C16L and B15R;gbkey=CDS;gene=OPG200;locus_tag=NBT03_gp168;product=Bcl-2-like protein;protein_id=YP_010377170.1 +NC_063383.1 RefSeq sequence_feature 172685 173697 . + . ID=id-NC_063383.1:172685..173697;exon_number=OPG201;gbkey=misc_feature;number=OPG201 +NC_063383.1 RefSeq sequence_feature 173744 174187 . - . ID=id-NC_063383.1:173744..174187;exon_number=OPG202;gbkey=misc_feature;number=OPG202 +NC_063383.1 RefSeq sequence_feature 174328 174456 . + . ID=id-NC_063383.1:174328..174456;exon_number=OPG203;gbkey=misc_feature;number=OPG203 +NC_063383.1 RefSeq gene 174532 175587 . + . ID=gene-NBT03_gp169;Dbxref=GeneID:72551585;Name=OPG204;gbkey=Gene;gene=OPG204;gene_biotype=protein_coding;locus_tag=NBT03_gp169;old_locus_tag=MPXV-M5312_HM12_Rivers-177 +NC_063383.1 RefSeq CDS 174532 175587 . + 0 ID=cds-YP_010377172.1;Parent=gene-NBT03_gp169;Dbxref=GenBank:YP_010377172.1,GeneID:72551585;Name=OPG204;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp177%3B cell surface antigen and secreted IFN-a%3B IFN-alpha/beta receptor glycoprotein%3B similar to VACV-WR B16R and VACV-Cop B19R;gbkey=CDS;gene=OPG204;locus_tag=NBT03_gp169;product=IFN-alpha/beta-receptor-like secreted glycoprotein;protein_id=YP_010377172.1 +NC_063383.1 RefSeq gene 175656 178019 . + . ID=gene-NBT03_gp170;Dbxref=GeneID:72551586;Name=OPG205;gbkey=Gene;gene=OPG205;gene_biotype=protein_coding;locus_tag=NBT03_gp170;old_locus_tag=MPXV-M5312_HM12_Rivers-178 +NC_063383.1 RefSeq CDS 175656 178019 . + 0 ID=cds-YP_010377173.1;Parent=gene-NBT03_gp170;Dbxref=GenBank:YP_010377173.1,GeneID:72551586;Name=OPG205;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp178%3B ankyrin-like%3B similar to VACV-WR B17R and VACV-Cop B20R;gbkey=CDS;gene=OPG205;locus_tag=NBT03_gp170;product=Ankyrin repeat protein (44);protein_id=YP_010377173.1 +NC_063383.1 RefSeq sequence_feature 178118 178916 . + . ID=id-NC_063383.1:178118..178916;exon_number=OPG206;gbkey=misc_feature;number=OPG206 +NC_063383.1 RefSeq gene 179266 180339 . + . ID=gene-NBT03_gp171;Dbxref=GeneID:72551587;Name=OPG208;gbkey=Gene;gene=OPG208;gene_biotype=protein_coding;locus_tag=NBT03_gp171;old_locus_tag=MPXV-M5312_HM12_Rivers-180 +NC_063383.1 RefSeq CDS 179266 180339 . + 0 ID=cds-YP_010377174.1;Parent=gene-NBT03_gp171;Dbxref=GenBank:YP_010377174.1,GeneID:72551587;Name=OPG208;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp180%3B serine protease inhibitor-like%2C SPI-1%3B apoptosis inhibition%3B Serpin 1%2C2%2C3%3B Actual start may be at position 179%2C074%3B annotated start of ORF is missing approx. 17 AA compared to CPXVs%3B similar to VACV-WR B19R and VACV-Cop K2L;gbkey=CDS;gene=OPG208;locus_tag=NBT03_gp171;product=Serpin;protein_id=YP_010377174.1 +NC_063383.1 RefSeq gene 180518 181090 . + . ID=gene-NBT03_gp172;Dbxref=GeneID:72551588;Name=OPG209;gbkey=Gene;gene=OPG209;gene_biotype=protein_coding;locus_tag=NBT03_gp172;old_locus_tag=MPXV-M5312_HM12_Rivers-181 +NC_063383.1 RefSeq CDS 180518 181090 . + 0 ID=cds-YP_010377175.1;Parent=gene-NBT03_gp172;Dbxref=GenBank:YP_010377175.1,GeneID:72551588;Name=OPG209;Note=Old product: MPXVgp181%3B Hypothetical protein%3B similar to VACV-WR B20R and VACV-Cop C14L;gbkey=CDS;gene=OPG209;locus_tag=NBT03_gp172;product=Virulence protein;protein_id=YP_010377175.1 +NC_063383.1 RefSeq gene 181356 186998 . + . ID=gene-NBT03_gp173;Dbxref=GeneID:72551589;Name=OPG210;gbkey=Gene;gene=OPG210;gene_biotype=protein_coding;locus_tag=NBT03_gp173;old_locus_tag=MPXV-M5312_HM12_Rivers-182 +NC_063383.1 RefSeq CDS 181356 186998 . + 0 ID=cds-YP_010377176.1;Parent=gene-NBT03_gp173;Dbxref=GenBank:YP_010377176.1,GeneID:72551589;Name=OPG210;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp182%3B Surface glycoprotein%3B putative membrane-associated glycoprotein%3B cadherin-like domain%3B similar to VACV-WR B21R;gbkey=CDS;gene=OPG210;locus_tag=NBT03_gp173;product=B22R family protein;protein_id=YP_010377176.1 +NC_063383.1 RefSeq sequence_feature 187317 187743 . + . ID=id-NC_063383.1:187317..187743;exon_number=OPG212;gbkey=misc_feature;number=OPG212 +NC_063383.1 RefSeq sequence_feature 187822 188298 . + . ID=id-NC_063383.1:187822..188298;exon_number=OPG213;gbkey=misc_feature;number=OPG213 +NC_063383.1 RefSeq sequence_feature 188458 188963 . + . ID=id-NC_063383.1:188458..188963;exon_number=OPG214;gbkey=misc_feature;number=OPG214 +NC_063383.1 RefSeq gene 189199 189660 . + . ID=gene-NBT03_gp174;Dbxref=GeneID:72551590;Name=OPG005;gbkey=Gene;gene=OPG005;gene_biotype=protein_coding;locus_tag=NBT03_gp174;old_locus_tag=MPXV-M5312_HM12_Rivers-184 +NC_063383.1 RefSeq CDS 189199 189660 . + 0 ID=cds-YP_010377177.1;Parent=gene-NBT03_gp174;Dbxref=GenBank:YP_010377177.1,GeneID:72551590;Name=OPG005;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp185%3B VAC B15R-like%3B Hypothetical protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR N1R and VACV-Cop C16L and B22R;gbkey=CDS;gene=OPG005;locus_tag=NBT03_gp174;product=Bcl-2-like protein;protein_id=YP_010377177.1 +NC_063383.1 RefSeq gene 190410 190940 . + . ID=gene-NBT03_gp175;Dbxref=GeneID:72551591;Name=OPG016;gbkey=Gene;gene=OPG016;gene_biotype=protein_coding;locus_tag=NBT03_gp175;old_locus_tag=MPXV-M5312_HM12_Rivers-186 +NC_063383.1 RefSeq CDS 190410 190940 . + 0 ID=cds-YP_010377184.1;Parent=gene-NBT03_gp175;Dbxref=GenBank:YP_010377184.1,GeneID:72551591;Name=OPG016;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp187%3B similar to VACV-WR N3R;gbkey=CDS;gene=OPG016;locus_tag=NBT03_gp175;product=Brix domain protein;protein_id=YP_010377184.1 +NC_063383.1 RefSeq long_terminal_repeat 190788 197209 . + . ID=id-NC_063383.1:190788..197209;gbkey=repeat_region;rpt_type=long_terminal_repeat +NC_063383.1 RefSeq gene 191054 192367 . + . ID=gene-NBT03_gp176;Dbxref=GeneID:72551592;Name=OPG015_dup;gbkey=Gene;gene=OPG015_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp176;old_locus_tag=MPXV-M5312_HM12_Rivers-187 +NC_063383.1 RefSeq CDS 191054 192367 . + 0 ID=cds-YP_010377179.1;Parent=gene-NBT03_gp176;Dbxref=GenBank:YP_010377179.1,GeneID:72551592;Name=OPG015_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp188%3B ankyrin-like%3B Ankyrin (CPXV-017)%3B similar to VACV-WR N4R;gbkey=CDS;gene=OPG015_dup;locus_tag=NBT03_gp176;product=Ankyrin repeat protein (39);protein_id=YP_010377179.1 +NC_063383.1 RefSeq gene 192603 194369 . + . ID=gene-NBT03_gp177;Dbxref=GeneID:72551593;Name=OPG003_dup;gbkey=Gene;gene=OPG003_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp177;old_locus_tag=MPXV-M5312_HM12_Rivers-188 +NC_063383.1 RefSeq CDS 192603 194369 . + 0 ID=cds-YP_010377180.1;Parent=gene-NBT03_gp177;Dbxref=GenBank:YP_010377180.1,GeneID:72551593;Name=OPG003_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp189%3B ankyrin-like%3B similar to VACV-WR J1R and VACV-Cop C19L;gbkey=CDS;gene=OPG003_dup;locus_tag=NBT03_gp177;product=Ankyrin repeat protein (25);protein_id=YP_010377180.1 +NC_063383.1 RefSeq gene 194459 195508 . + . ID=gene-NBT03_gp178;Dbxref=GeneID:72551594;Name=OPG002_dup;gbkey=Gene;gene=OPG002_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp178;old_locus_tag=MPXV-M5312_HM12_Rivers-189 +NC_063383.1 RefSeq CDS 194459 195508 . + 0 ID=cds-YP_010377181.1;Parent=gene-NBT03_gp178;Dbxref=GenBank:YP_010377181.1,GeneID:72551594;Name=OPG002_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp190%3B secreted TNF binding protein%3B TNF receptor (CrmB)%3B similar to VACV-WR J2R and VACV-Cop C22L;gbkey=CDS;gene=OPG002_dup;locus_tag=NBT03_gp178;product=Crm-B secreted TNF-alpha-receptor-like protein;protein_id=YP_010377181.1 +NC_063383.1 RefSeq gene 195635 196375 . + . ID=gene-NBT03_gp179;Dbxref=GeneID:72551595;Name=OPG001_dup;gbkey=Gene;gene=OPG001_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp179;old_locus_tag=MPXV-M5312_HM12_Rivers-190 +NC_063383.1 RefSeq CDS 195635 196375 . + 0 ID=cds-YP_010377182.1;Parent=gene-NBT03_gp179;Dbxref=GenBank:YP_010377182.1,GeneID:72551595;Name=OPG001_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp191%3B Chemokine binding protein (Cop-C23L)%3B most abundant secreted protein%3B CC-chemokine binding protein%3B similar to VACV-WR J3R and VACV-Cop C23L and B29R;gbkey=CDS;gene=OPG001_dup;locus_tag=NBT03_gp179;product=Chemokine binding protein;protein_id=YP_010377182.1 diff --git a/data/nextstrain/mpox/all-clades/pathogen.json b/data/nextstrain/mpox/all-clades/pathogen.json new file mode 100644 index 00000000..e3f51617 --- /dev/null +++ b/data/nextstrain/mpox/all-clades/pathogen.json @@ -0,0 +1,212 @@ +{ + "alignmentParams": { + "excessBandwidth": 100, + "terminalBandwidth": 300, + "allowedMismatches": 8, + "windowSize": 40, + "minSeedCover": 0.1, + "gapAlignmentSide": "left" + }, + "attributes": { + "name": "Mpox virus (All clades)", + "reference accession": "NC_063383.1", + "reference name": "MPXV-M5312_HM12_Rivers" + }, + "compatibility": { + "cli": "3.0.0-alpha.0", + "web": "3.0.0-alpha.0" + }, + "deprecated": false, + "enabled": true, + "experimental": false, + "files": { + "changelog": "CHANGELOG.md", + "examples": "sequences.fasta", + "genomeAnnotation": "genome_annotation.gff3", + "pathogenJson": "pathogen.json", + "readme": "README.md", + "reference": "reference.fasta", + "treeJson": "tree.json" + }, + "official": true, + "qc": { + "frameShifts": { + "enabled": true, + "ignoredFrameShifts": [ + { + "codonRange": { + "begin": 3, + "end": 589 + }, + "geneName": "OPG003" + }, + { + "codonRange": { + "begin": 3, + "end": 589 + }, + "geneName": "OPG003_dup" + }, + { + "codonRange": { + "begin": 281, + "end": 285 + }, + "geneName": "OPG105" + }, + { + "codonRange": { + "begin": 227, + "end": 229 + }, + "geneName": "OPG164" + }, + { + "codonRange": { + "begin": 554, + "end": 560 + }, + "geneName": "OPG180" + }, + { + "codonRange": { + "begin": 42, + "end": 101 + }, + "geneName": "OPG197" + }, + { + "codonRange": { + "begin": 443, + "end": 443 + }, + "geneName": "OPG037" + }, + { + "codonRange": { + "begin": 57, + "end": 443 + }, + "geneName": "OPG037" + }, + { + "codonRange": { + "begin": 481, + "end": 483 + }, + "geneName": "OPG047" + }, + { + "codonRange": { + "begin": 482, + "end": 483 + }, + "geneName": "OPG047" + }, + { + "codonRange": { + "begin": 72, + "end": 76 + }, + "geneName": "OPG050" + }, + { + "codonRange": { + "begin": 369, + "end": 371 + }, + "geneName": "OPG153" + }, + { + "codonRange": { + "begin": 370, + "end": 371 + }, + "geneName": "OPG153" + }, + { + "codonRange": { + "begin": 166, + "end": 169 + }, + "geneName": "OPG191" + }, + { + "codonRange": { + "begin": 72, + "end": 222 + }, + "geneName": "OPG195" + }, + { + "codonRange": { + "begin": 208, + "end": 222 + }, + "geneName": "OPG195" + }, + { + "codonRange": { + "begin": 289, + "end": 346 + }, + "geneName": "OPG174" + } + ], + "scoreWeight": 20 + }, + "missingData": { + "enabled": true, + "missingDataThreshold": 20000, + "scoreBias": 1000 + }, + "mixedSites": { + "enabled": true, + "mixedSitesThreshold": 40 + }, + "privateMutations": { + "cutoff": 300, + "enabled": true, + "typical": 50, + "weightLabeledSubstitutions": 6, + "weightReversionSubstitutions": 6, + "weightUnlabeledSubstitutions": 1 + }, + "snpClusters": { + "clusterCutOff": 10, + "enabled": false, + "scoreWeight": 10, + "windowSize": 100 + }, + "stopCodons": { + "enabled": true, + "ignoredStopCodons": [ + { + "codon": 187, + "geneName": "OPG015_dup" + }, + { + "codon": 187, + "geneName": "OPG015" + }, + { + "codon": 21, + "geneName": "OPG176" + }, + { + "codon": 299, + "geneName": "OPG187" + }, + { + "codon": 48, + "geneName": "OPG059" + } + ], + "scoreWeight": 20 + } + }, + "schemaVersion": "3.0.0", + "version": { + "tag": "unreleased" + } +} diff --git a/data/nextstrain/mpox/all-clades/reference.fasta b/data/nextstrain/mpox/all-clades/reference.fasta new file mode 100644 index 00000000..0f1d13ac --- /dev/null +++ b/data/nextstrain/mpox/all-clades/reference.fasta @@ -0,0 +1,2 @@ +>NC_063383.1 Monkeypox virus, complete genome +ATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTAACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATTTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAAACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACAAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTTGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAAT diff --git a/data/nextstrain/mpx/mpxv/ancestral/sequences.fasta b/data/nextstrain/mpox/all-clades/sequences.fasta similarity index 100% rename from data/nextstrain/mpx/mpxv/ancestral/sequences.fasta rename to data/nextstrain/mpox/all-clades/sequences.fasta diff --git a/data/nextstrain/mpox/all-clades/tree.json b/data/nextstrain/mpox/all-clades/tree.json new file mode 100644 index 00000000..d9b86d19 --- /dev/null +++ b/data/nextstrain/mpox/all-clades/tree.json @@ -0,0 +1 @@ +{"version":"v2","meta":{"title":"Nextclade reference tree for Mpox virus (All clades) dataset","updated":"2023-11-21","build_url":"https://github.com/nextstrain/mpox/nextclade","data_provenance":[{"name":"GenBank","url":"https://www.ncbi.nlm.nih.gov/genbank/"}],"maintainers":[{"name":"Cornelius Roemer","url":"https://neherlab.org"},{"name":"Richard Neher","url":"https://neherlab.org"},{"name":"Nextstrain team","url":"https://nextstrain.org"}],"display_defaults":{"color_by":"clade_membership","map_triplicate":false,"distance_measure":"div","tip_label":"strain_display","transmission_lines":false},"genome_annotations":{"OPG001":{"end":1575,"seqid":"resources/genome_annotation.gff3","start":835,"strand":"-","type":"gene"},"OPG001_dup":{"end":196375,"seqid":"resources/genome_annotation.gff3","start":195635,"strand":"+","type":"gene"},"OPG002":{"end":2751,"seqid":"resources/genome_annotation.gff3","start":1702,"strand":"-","type":"gene"},"OPG002_dup":{"end":195508,"seqid":"resources/genome_annotation.gff3","start":194459,"strand":"+","type":"gene"},"OPG003":{"end":4607,"seqid":"resources/genome_annotation.gff3","start":2841,"strand":"-","type":"gene"},"OPG003_dup":{"end":194369,"seqid":"resources/genome_annotation.gff3","start":192603,"strand":"+","type":"gene"},"OPG005":{"end":189660,"seqid":"resources/genome_annotation.gff3","start":189199,"strand":"+","type":"gene"},"OPG015":{"end":6156,"seqid":"resources/genome_annotation.gff3","start":4843,"strand":"-","type":"gene"},"OPG015_dup":{"end":192367,"seqid":"resources/genome_annotation.gff3","start":191054,"strand":"+","type":"gene"},"OPG016":{"end":190940,"seqid":"resources/genome_annotation.gff3","start":190410,"strand":"+","type":"gene"},"OPG019":{"end":8008,"seqid":"resources/genome_annotation.gff3","start":7580,"strand":"+","type":"gene"},"OPG021":{"end":10315,"seqid":"resources/genome_annotation.gff3","start":9587,"strand":"+","type":"gene"},"OPG022":{"end":10858,"seqid":"resources/genome_annotation.gff3","start":10478,"strand":"-","type":"gene"},"OPG023":{"end":12900,"seqid":"resources/genome_annotation.gff3","start":10918,"strand":"-","type":"gene"},"OPG024":{"end":13228,"seqid":"resources/genome_annotation.gff3","start":13034,"strand":"-","type":"gene"},"OPG025":{"end":15267,"seqid":"resources/genome_annotation.gff3","start":13375,"strand":"-","type":"gene"},"OPG027":{"end":16377,"seqid":"resources/genome_annotation.gff3","start":15925,"strand":"-","type":"gene"},"OPG029":{"end":17069,"seqid":"resources/genome_annotation.gff3","start":16602,"strand":"-","type":"gene"},"OPG030":{"end":17833,"seqid":"resources/genome_annotation.gff3","start":17213,"strand":"-","type":"gene"},"OPG031":{"end":18828,"seqid":"resources/genome_annotation.gff3","start":17878,"strand":"-","type":"gene"},"OPG034":{"end":20005,"seqid":"resources/genome_annotation.gff3","start":19361,"strand":"-","type":"gene"},"OPG035":{"end":20404,"seqid":"resources/genome_annotation.gff3","start":20051,"strand":"-","type":"gene"},"OPG036":{"end":21064,"seqid":"resources/genome_annotation.gff3","start":20531,"strand":"-","type":"gene"},"OPG037":{"end":22433,"seqid":"resources/genome_annotation.gff3","start":21105,"strand":"-","type":"gene"},"OPG038":{"end":23159,"seqid":"resources/genome_annotation.gff3","start":22497,"strand":"-","type":"gene"},"OPG039":{"end":24118,"seqid":"resources/genome_annotation.gff3","start":23264,"strand":"-","type":"gene"},"OPG040":{"end":25478,"seqid":"resources/genome_annotation.gff3","start":24351,"strand":"-","type":"gene"},"OPG042":{"end":27097,"seqid":"resources/genome_annotation.gff3","start":25823,"strand":"-","type":"gene"},"OPG043":{"end":27955,"seqid":"resources/genome_annotation.gff3","start":27125,"strand":"-","type":"gene"},"OPG044":{"end":28540,"seqid":"resources/genome_annotation.gff3","start":28091,"strand":"+","type":"gene"},"OPG045":{"end":29262,"seqid":"resources/genome_annotation.gff3","start":28603,"strand":"-","type":"gene"},"OPG046":{"end":29729,"seqid":"resources/genome_annotation.gff3","start":29274,"strand":"-","type":"gene"},"OPG047":{"end":31194,"seqid":"resources/genome_annotation.gff3","start":29746,"strand":"-","type":"gene"},"OPG048":{"end":32164,"seqid":"resources/genome_annotation.gff3","start":31205,"strand":"-","type":"gene"},"OPG049":{"end":33151,"seqid":"resources/genome_annotation.gff3","start":32195,"strand":"-","type":"gene"},"OPG050":{"end":33408,"seqid":"resources/genome_annotation.gff3","start":33181,"strand":"-","type":"gene"},"OPG051":{"end":33649,"seqid":"resources/genome_annotation.gff3","start":33425,"strand":"-","type":"gene"},"OPG052":{"end":33995,"seqid":"resources/genome_annotation.gff3","start":33801,"strand":"-","type":"gene"},"OPG053":{"end":34690,"seqid":"resources/genome_annotation.gff3","start":34052,"strand":"-","type":"gene"},"OPG054":{"end":35996,"seqid":"resources/genome_annotation.gff3","start":34677,"strand":"-","type":"gene"},"OPG055":{"end":37083,"seqid":"resources/genome_annotation.gff3","start":36019,"strand":"-","type":"gene"},"OPG056":{"end":39034,"seqid":"resources/genome_annotation.gff3","start":37127,"strand":"-","type":"gene"},"OPG057":{"end":40195,"seqid":"resources/genome_annotation.gff3","start":39077,"strand":"-","type":"gene"},"OPG058":{"end":40434,"seqid":"resources/genome_annotation.gff3","start":40213,"strand":"-","type":"gene"},"OPG059":{"end":40633,"seqid":"resources/genome_annotation.gff3","start":40484,"strand":"-","type":"gene"},"OPG060":{"end":41182,"seqid":"resources/genome_annotation.gff3","start":40706,"strand":"-","type":"gene"},"OPG061":{"end":41884,"seqid":"resources/genome_annotation.gff3","start":41189,"strand":"-","type":"gene"},"OPG062":{"end":42252,"seqid":"resources/genome_annotation.gff3","start":41947,"strand":"+","type":"gene"},"OPG063":{"end":43688,"seqid":"resources/genome_annotation.gff3","start":42249,"strand":"-","type":"gene"},"OPG064":{"end":45898,"seqid":"resources/genome_annotation.gff3","start":43685,"strand":"-","type":"gene"},"OPG065":{"end":46483,"seqid":"resources/genome_annotation.gff3","start":46022,"strand":"-","type":"gene"},"OPG066":{"end":47428,"seqid":"resources/genome_annotation.gff3","start":46649,"strand":"-","type":"gene"},"OPG068":{"end":49904,"seqid":"resources/genome_annotation.gff3","start":48201,"strand":"+","type":"gene"},"OPG069":{"end":50486,"seqid":"resources/genome_annotation.gff3","start":49986,"strand":"+","type":"gene"},"OPG070":{"end":51411,"seqid":"resources/genome_annotation.gff3","start":50590,"strand":"+","type":"gene"},"OPG071":{"end":54438,"seqid":"resources/genome_annotation.gff3","start":51418,"strand":"-","type":"gene"},"OPG072":{"end":54757,"seqid":"resources/genome_annotation.gff3","start":54470,"strand":"+","type":"gene"},"OPG073":{"end":55141,"seqid":"resources/genome_annotation.gff3","start":54752,"strand":"-","type":"gene"},"OPG074":{"end":57125,"seqid":"resources/genome_annotation.gff3","start":55128,"strand":"-","type":"gene"},"OPG075":{"end":57498,"seqid":"resources/genome_annotation.gff3","start":57172,"strand":"-","type":"gene"},"OPG076":{"end":57630,"seqid":"resources/genome_annotation.gff3","start":57523,"strand":"-","type":"gene"},"OPG077":{"end":58583,"seqid":"resources/genome_annotation.gff3","start":57645,"strand":"-","type":"gene"},"OPG078":{"end":58811,"seqid":"resources/genome_annotation.gff3","start":58590,"strand":"-","type":"gene"},"OPG079":{"end":59621,"seqid":"resources/genome_annotation.gff3","start":58812,"strand":"-","type":"gene"},"OPG080":{"end":62018,"seqid":"resources/genome_annotation.gff3","start":59703,"strand":"-","type":"gene"},"OPG081":{"end":62285,"seqid":"resources/genome_annotation.gff3","start":62046,"strand":"-","type":"gene"},"OPG082":{"end":63452,"seqid":"resources/genome_annotation.gff3","start":62304,"strand":"-","type":"gene"},"OPG083":{"end":64716,"seqid":"resources/genome_annotation.gff3","start":63445,"strand":"-","type":"gene"},"OPG084":{"end":66752,"seqid":"resources/genome_annotation.gff3","start":64722,"strand":"+","type":"gene"},"OPG085":{"end":68531,"seqid":"resources/genome_annotation.gff3","start":66756,"strand":"-","type":"gene"},"OPG086":{"end":68863,"seqid":"resources/genome_annotation.gff3","start":68528,"strand":"-","type":"gene"},"OPG087":{"end":69519,"seqid":"resources/genome_annotation.gff3","start":68857,"strand":"+","type":"gene"},"OPG088":{"end":69863,"seqid":"resources/genome_annotation.gff3","start":69489,"strand":"-","type":"gene"},"OPG089":{"end":71170,"seqid":"resources/genome_annotation.gff3","start":69866,"strand":"+","type":"gene"},"OPG090":{"end":71370,"seqid":"resources/genome_annotation.gff3","start":71179,"strand":"+","type":"gene"},"OPG091":{"end":71867,"seqid":"resources/genome_annotation.gff3","start":71370,"strand":"+","type":"gene"},"OPG092":{"end":72947,"seqid":"resources/genome_annotation.gff3","start":71832,"strand":"-","type":"gene"},"OPG093":{"end":73760,"seqid":"resources/genome_annotation.gff3","start":72978,"strand":"+","type":"gene"},"OPG094":{"end":74802,"seqid":"resources/genome_annotation.gff3","start":73780,"strand":"+","type":"gene"},"OPG095":{"end":75555,"seqid":"resources/genome_annotation.gff3","start":74803,"strand":"+","type":"gene"},"OPG096":{"end":75865,"seqid":"resources/genome_annotation.gff3","start":75587,"strand":"+","type":"gene"},"OPG097":{"end":76875,"seqid":"resources/genome_annotation.gff3","start":75841,"strand":"-","type":"gene"},"OPG098":{"end":77655,"seqid":"resources/genome_annotation.gff3","start":76900,"strand":"+","type":"gene"},"OPG099":{"end":78051,"seqid":"resources/genome_annotation.gff3","start":77665,"strand":"+","type":"gene"},"OPG100":{"end":78466,"seqid":"resources/genome_annotation.gff3","start":78008,"strand":"+","type":"gene"},"OPG101":{"end":79019,"seqid":"resources/genome_annotation.gff3","start":78486,"strand":"+","type":"gene"},"OPG102":{"end":80086,"seqid":"resources/genome_annotation.gff3","start":79085,"strand":"+","type":"gene"},"OPG103":{"end":80558,"seqid":"resources/genome_annotation.gff3","start":80001,"strand":"+","type":"gene"},"OPG104":{"end":81019,"seqid":"resources/genome_annotation.gff3","start":80618,"strand":"-","type":"gene"},"OPG105":{"end":84986,"seqid":"resources/genome_annotation.gff3","start":81126,"strand":"+","type":"gene"},"OPG106":{"end":85498,"seqid":"resources/genome_annotation.gff3","start":84983,"strand":"-","type":"gene"},"OPG107":{"end":86081,"seqid":"resources/genome_annotation.gff3","start":85512,"strand":"+","type":"gene"},"OPG108":{"end":87059,"seqid":"resources/genome_annotation.gff3","start":86085,"strand":"-","type":"gene"},"OPG109":{"end":89447,"seqid":"resources/genome_annotation.gff3","start":87060,"strand":"-","type":"gene"},"OPG110":{"end":90264,"seqid":"resources/genome_annotation.gff3","start":89632,"strand":"+","type":"gene"},"OPG111":{"end":91209,"seqid":"resources/genome_annotation.gff3","start":90265,"strand":"+","type":"gene"},"OPG112":{"end":91687,"seqid":"resources/genome_annotation.gff3","start":91247,"strand":"+","type":"gene"},"OPG113":{"end":94268,"seqid":"resources/genome_annotation.gff3","start":91731,"strand":"+","type":"gene"},"OPG114":{"end":94667,"seqid":"resources/genome_annotation.gff3","start":94227,"strand":"-","type":"gene"},"OPG115":{"end":95361,"seqid":"resources/genome_annotation.gff3","start":94660,"strand":"+","type":"gene"},"OPG116":{"end":96017,"seqid":"resources/genome_annotation.gff3","start":95361,"strand":"+","type":"gene"},"OPG117":{"end":98406,"seqid":"resources/genome_annotation.gff3","start":96049,"strand":"+","type":"gene"},"OPG118":{"end":100359,"seqid":"resources/genome_annotation.gff3","start":98446,"strand":"+","type":"gene"},"OPG119":{"end":100871,"seqid":"resources/genome_annotation.gff3","start":100386,"strand":"+","type":"gene"},"OPG120":{"end":101748,"seqid":"resources/genome_annotation.gff3","start":100834,"strand":"-","type":"gene"},"OPG121":{"end":102431,"seqid":"resources/genome_annotation.gff3","start":101790,"strand":"+","type":"gene"},"OPG122":{"end":103174,"seqid":"resources/genome_annotation.gff3","start":102428,"strand":"+","type":"gene"},"OPG123":{"end":105070,"seqid":"resources/genome_annotation.gff3","start":103175,"strand":"-","type":"gene"},"OPG124":{"end":105968,"seqid":"resources/genome_annotation.gff3","start":105105,"strand":"-","type":"gene"},"OPG125":{"end":107654,"seqid":"resources/genome_annotation.gff3","start":105999,"strand":"-","type":"gene"},"OPG126":{"end":108130,"seqid":"resources/genome_annotation.gff3","start":107678,"strand":"-","type":"gene"},"OPG127":{"end":108825,"seqid":"resources/genome_annotation.gff3","start":108151,"strand":"-","type":"gene"},"OPG128":{"end":109055,"seqid":"resources/genome_annotation.gff3","start":108822,"strand":"-","type":"gene"},"OPG129":{"end":111004,"seqid":"resources/genome_annotation.gff3","start":109070,"strand":"-","type":"gene"},"OPG130":{"end":111902,"seqid":"resources/genome_annotation.gff3","start":111057,"strand":"-","type":"gene"},"OPG131":{"end":112425,"seqid":"resources/genome_annotation.gff3","start":111940,"strand":"+","type":"gene"},"OPG132":{"end":113540,"seqid":"resources/genome_annotation.gff3","start":112422,"strand":"-","type":"gene"},"OPG133":{"end":115696,"seqid":"resources/genome_annotation.gff3","start":113564,"strand":"-","type":"gene"},"OPG134":{"end":116628,"seqid":"resources/genome_annotation.gff3","start":115750,"strand":"+","type":"gene"},"OPG135":{"end":116911,"seqid":"resources/genome_annotation.gff3","start":116609,"strand":"-","type":"gene"},"OPG136":{"end":119587,"seqid":"resources/genome_annotation.gff3","start":116912,"strand":"-","type":"gene"},"OPG137":{"end":120558,"seqid":"resources/genome_annotation.gff3","start":119602,"strand":"+","type":"gene"},"OPG138":{"end":121132,"seqid":"resources/genome_annotation.gff3","start":120560,"strand":"-","type":"gene"},"OPG139":{"end":121368,"seqid":"resources/genome_annotation.gff3","start":121156,"strand":"-","type":"gene"},"OPG140":{"end":121746,"seqid":"resources/genome_annotation.gff3","start":121474,"strand":"-","type":"gene"},"OPG141":{"end":121924,"seqid":"resources/genome_annotation.gff3","start":121763,"strand":"-","type":"gene"},"OPG142":{"end":122198,"seqid":"resources/genome_annotation.gff3","start":121914,"strand":"-","type":"gene"},"OPG143":{"end":123315,"seqid":"resources/genome_annotation.gff3","start":122182,"strand":"-","type":"gene"},"OPG144":{"end":123932,"seqid":"resources/genome_annotation.gff3","start":123318,"strand":"-","type":"gene"},"OPG145":{"end":125425,"seqid":"resources/genome_annotation.gff3","start":123947,"strand":"+","type":"gene"},"OPG146":{"end":125639,"seqid":"resources/genome_annotation.gff3","start":125406,"strand":"-","type":"gene"},"OPG147":{"end":125987,"seqid":"resources/genome_annotation.gff3","start":125640,"strand":"-","type":"gene"},"OPG148":{"end":127266,"seqid":"resources/genome_annotation.gff3","start":125986,"strand":"+","type":"gene"},"OPG149":{"end":127759,"seqid":"resources/genome_annotation.gff3","start":127196,"strand":"+","type":"gene"},"OPG150":{"end":128927,"seqid":"resources/genome_annotation.gff3","start":127779,"strand":"+","type":"gene"},"OPG151":{"end":132418,"seqid":"resources/genome_annotation.gff3","start":128924,"strand":"+","type":"gene"},"OPG153":{"end":137667,"seqid":"resources/genome_annotation.gff3","start":136138,"strand":"-","type":"gene"},"OPG154":{"end":138050,"seqid":"resources/genome_annotation.gff3","start":137718,"strand":"-","type":"gene"},"OPG155":{"end":138491,"seqid":"resources/genome_annotation.gff3","start":138051,"strand":"-","type":"gene"},"OPG156":{"end":139409,"seqid":"resources/genome_annotation.gff3","start":138492,"strand":"-","type":"gene"},"OPG157":{"end":139608,"seqid":"resources/genome_annotation.gff3","start":139372,"strand":"-","type":"gene"},"OPG158":{"end":139769,"seqid":"resources/genome_annotation.gff3","start":139641,"strand":"-","type":"gene"},"OPG159":{"end":140205,"seqid":"resources/genome_annotation.gff3","start":139768,"strand":"+","type":"gene"},"OPG160":{"end":141074,"seqid":"resources/genome_annotation.gff3","start":140172,"strand":"-","type":"gene"},"OPG161":{"end":141647,"seqid":"resources/genome_annotation.gff3","start":141102,"strand":"+","type":"gene"},"OPG162":{"end":142158,"seqid":"resources/genome_annotation.gff3","start":141652,"strand":"+","type":"gene"},"OPG163":{"end":142732,"seqid":"resources/genome_annotation.gff3","start":142202,"strand":"+","type":"gene"},"OPG164":{"end":143464,"seqid":"resources/genome_annotation.gff3","start":142778,"strand":"+","type":"gene"},"OPG165":{"end":144322,"seqid":"resources/genome_annotation.gff3","start":143516,"strand":"+","type":"gene"},"OPG166":{"end":144577,"seqid":"resources/genome_annotation.gff3","start":144398,"strand":"+","type":"gene"},"OPG167":{"end":145407,"seqid":"resources/genome_annotation.gff3","start":144574,"strand":"-","type":"gene"},"OPG170":{"end":146778,"seqid":"resources/genome_annotation.gff3","start":146113,"strand":"-","type":"gene"},"OPG171":{"end":147389,"seqid":"resources/genome_annotation.gff3","start":146988,"strand":"+","type":"gene"},"OPG172":{"end":148017,"seqid":"resources/genome_annotation.gff3","start":147427,"strand":"+","type":"gene"},"OPG173":{"end":148261,"seqid":"resources/genome_annotation.gff3","start":148037,"strand":"+","type":"gene"},"OPG174":{"end":149395,"seqid":"resources/genome_annotation.gff3","start":148355,"strand":"-","type":"gene"},"OPG175":{"end":149819,"seqid":"resources/genome_annotation.gff3","start":149442,"strand":"+","type":"gene"},"OPG176":{"end":150531,"seqid":"resources/genome_annotation.gff3","start":149809,"strand":"+","type":"gene"},"OPG178":{"end":152123,"seqid":"resources/genome_annotation.gff3","start":151509,"strand":"+","type":"gene"},"OPG180":{"end":154371,"seqid":"resources/genome_annotation.gff3","start":152692,"strand":"+","type":"gene"},"OPG181":{"end":155416,"seqid":"resources/genome_annotation.gff3","start":154412,"strand":"+","type":"gene"},"OPG185":{"end":159858,"seqid":"resources/genome_annotation.gff3","start":158917,"strand":"+","type":"gene"},"OPG187":{"end":161533,"seqid":"resources/genome_annotation.gff3","start":160622,"strand":"+","type":"gene"},"OPG188":{"end":163107,"seqid":"resources/genome_annotation.gff3","start":161596,"strand":"+","type":"gene"},"OPG189":{"end":165018,"seqid":"resources/genome_annotation.gff3","start":163333,"strand":"+","type":"gene"},"OPG190":{"end":166075,"seqid":"resources/genome_annotation.gff3","start":165122,"strand":"+","type":"gene"},"OPG191":{"end":166667,"seqid":"resources/genome_annotation.gff3","start":166161,"strand":"+","type":"gene"},"OPG192":{"end":167279,"seqid":"resources/genome_annotation.gff3","start":166731,"strand":"+","type":"gene"},"OPG193":{"end":168137,"seqid":"resources/genome_annotation.gff3","start":167334,"strand":"+","type":"gene"},"OPG195":{"end":168895,"seqid":"resources/genome_annotation.gff3","start":168230,"strand":"+","type":"gene"},"OPG197":{"end":169972,"seqid":"resources/genome_annotation.gff3","start":169670,"strand":"+","type":"gene"},"OPG198":{"end":170886,"seqid":"resources/genome_annotation.gff3","start":170038,"strand":"+","type":"gene"},"OPG199":{"end":172022,"seqid":"resources/genome_annotation.gff3","start":170988,"strand":"+","type":"gene"},"OPG200":{"end":172599,"seqid":"resources/genome_annotation.gff3","start":172150,"strand":"+","type":"gene"},"OPG204":{"end":175587,"seqid":"resources/genome_annotation.gff3","start":174532,"strand":"+","type":"gene"},"OPG205":{"end":178019,"seqid":"resources/genome_annotation.gff3","start":175656,"strand":"+","type":"gene"},"OPG208":{"end":180339,"seqid":"resources/genome_annotation.gff3","start":179266,"strand":"+","type":"gene"},"OPG209":{"end":181090,"seqid":"resources/genome_annotation.gff3","start":180518,"strand":"+","type":"gene"},"OPG210":{"end":186998,"seqid":"resources/genome_annotation.gff3","start":181356,"strand":"+","type":"gene"},"nuc":{"end":197209,"start":1,"strand":"+","type":"source"}},"colorings":[{"key":"clade_membership","title":"Clade","type":"categorical","scale":[["I","#4A8CC2"],["II","#71B486"],["IIa","#ABBD52"],["IIb","#DEA73C"]]},{"key":"gt","title":"Genotype","type":"categorical"},{"key":"outbreak","title":"Outbreak","type":"categorical","scale":[["hMPXV-1","#4C90C0"]]},{"key":"lineage","title":"Lineage","type":"categorical","scale":[["A","#5E1D9D"],["A.1","#4D22AE"],["A.1.1","#4531BC"],["B.1","#4041C7"],["B.1.1","#3F53CD"],["B.1.2","#4064CF"],["B.1.3","#4375CD"],["C.1","#4784C8"],["B.1.4","#4C91BF"],["B.1.5","#539CB4"],["B.1.6","#5AA5A7"],["B.1.7","#63AC9A"],["B.1.8","#6CB28C"],["B.1.9","#77B67E"],["B.1.10","#82BA71"],["B.1.11","#8FBC66"],["B.1.12","#9CBE5B"],["B.1.13","#A9BD53"],["B.1.14","#B5BD4C"],["B.1.15","#C1BA46"],["B.1.16","#CDB642"],["B.1.17","#D6B03F"],["B.1.18","#DEA73B"],["B.1.19","#E39B39"],["B.1.20","#E68D36"],["A.2","#E67C33"],["A.2.1","#E5692F"],["A.2.2","#E1532B"],["A.2.3","#DE3E27"],["A.3","#DB2823"]]},{"key":"date","title":"Collection Date","type":"categorical"},{"key":"host","title":"Host","type":"categorical"},{"key":"strain","title":"Strain name","type":"categorical"},{"key":"strain_display","title":"Pretty strain name","type":"categorical"},{"key":"region","title":"Region","type":"categorical","scale":[["Asia","#447CCD"],["Oceania","#5EA9A1"],["Africa","#8ABB6A"],["Europe","#BEBB48"],["South America","#E29E39"],["North America","#E2562B"]]},{"key":"country","title":"Country","type":"categorical","scale":[["Israel","#5E1D9D"],["Singapore","#4F1FAA"],["Vietnam","#4929B4"],["Taiwan","#4333BE"],["South Korea","#403FC6"],["Japan","#3F4CCB"],["Australia","#3E59CF"],["Sierra Leone","#4066CF"],["Liberia","#4272CE"],["Côte d'Ivoire","#447ECC"],["Benin","#4887C6"],["Nigeria","#4C91C0"],["Gabon","#5199B8"],["Cameroon","#56A0AF"],["Republic of the Congo","#5BA7A6"],["Central African Republic","#62AB9C"],["Democratic Republic of the Congo","#69B091"],["South Africa","#70B487"],["Portugal","#78B67E"],["Ireland","#80B974"],["Spain","#89BB6B"],["United Kingdom","#92BC63"],["France","#9BBE5B"],["Belgium","#A4BE56"],["Netherlands","#AEBD50"],["Switzerland","#B7BD4B"],["Germany","#C0BB47"],["Italy","#C8B843"],["Slovenia","#D0B441"],["Sweden","#D6AF3E"],["Austria","#DDAA3C"],["Czech Republic","#E0A23A"],["Slovakia","#E49938"],["Romania","#E68F36"],["Finland","#E68234"],["Brazil","#E67631"],["Peru","#E4672E"],["Colombia","#E2572B"],["Mexico","#DF4728"],["USA","#DD3826"],["Canada","#DB2823"]]}],"filters":["clade_membership","lineage","country","host","institution","region","strain_display","strain","date","outbreak"],"panels":["tree","entropy"],"extensions":{"nextclade":{"clade_node_attrs":[{"name":"outbreak","displayName":"Outbreak","description":""},{"name":"lineage","displayName":"Lineage","description":""}],"placement_mask_ranges":[{"begin":0,"end":1500},{"begin":133050,"end":133250},{"begin":136500,"end":136600},{"begin":140050,"end":140250},{"begin":146750,"end":147000},{"begin":150500,"end":150650},{"begin":169250,"end":169500},{"begin":169700,"end":169800},{"begin":173150,"end":173350},{"begin":179000,"end":179300},{"begin":190787,"end":197209}]}}},"tree":{"name":"NODE_0000000","node_attrs":{"div":0,"clade_membership":{"value":"outgroup"}},"branch_attrs":{"mutations":{"nuc":["T128C","T466C","C630A","T720C","A1093G","C1201T","A1504G","A1687G","A1813C","T1814G","T2086G","C2391A","T2554C","T3099G","A3420G","A3450G","G4691A","T4836G","G5751A","A6076G","A6146G","C6429T","T6430A","C6904T","T6976-","C6978T","T7005C","T7648C","T7810C","T7950G","A8066G","C8286T","T8422C","T8694G","A8893C","T8923C","T9161G","A9376G","T9509A","G9698A","A10267C","A10275G","C10641T","T10992C","T11439C","A11593G","A11624G","A12003G","C12324A","A12352G","A12380G","T12418G","A12712G","A12733G","T13135C","C13223A","G13348A","T13995C","G13999T","C14091T","T14431C","G15602A","T15794C","T16393G","A16406G","G16581A","G16608A","A16634G","T16788G","C17496T","T17800C","A18017T","A18312G","A18478C","A18769G","T18861A","T18953C","T19055C","T19290C","A19304T","T19367C","A19392C","T19457C","A19475G","A20605G","A20990T","A21034G","A21191G","T22575G","C22928T","T23080G","A23171G","T23172A","A23173G","G23175A","C23176A","A24032G","T24179C","T24222C","T24358G","G24719C","T25173G","G25212T","A25407G","G25769T","T25856C","G27215A","T27614C","T27949C","A28090C","T28175C","A28532T","A28548G","C28710T","C29446T","T29655C","T29758C","A30500T","G31039A","A31102G","G31144A","G31793A","G32364A","A32477C","T32867C","T33043C","T33102A","T33143C","A33656C","A33708C","T33963C","C34005T","A34295G","A34301C","T34685C","A35613G","T36049C","C37170T","A38067G","T39072A","T39248C","T40558G","T40565C","C40937T","C41967T","T42516A","A42769G","T43751C","A44972T","A45500G","A45584G","C45637A","A46217G","T46417C","A46427C","A46895G","G47140T","T47181C","G47735T","G48138A","C48148A","A48527C","T49223G","C49994T","C50595A","T51168C","T52354G","T52684C","T52938C","C52989A","A53156G","A53207C","G53257A","T55188C","A55203G","T55805C","T56531C","T58035G","T58131C","T58467C","T58965C","A59046G","T59256C","C59488T","A59709G","C60874G","A61056C","T62823C","T63156C","T63303C","G63976A","A64465G","T65352A","A65663G","A66263G","A66580G","A66761C","T67245C","T67550C","T67827C","G69675T","A72261G","A73076G","A73821G","G74303C","T74382C","A75790G","T76123C","A76198G","A76648G","A76911G","A78461C","A78641G","A78728C","A78942G","C79267T","C79502A","A79829G","G80756A","T80986C","A81063G","C81182T","T81463G","A81977G","C81989T","A82838T","T83360C","T83843C","A84333G","A84395G","T85163C","C85763T","A86225G","G86502T","A86535G","A87049G","T87501C","C87584T","A87735G","A88773G","T89214C","T89579G","A90493G","T90891C","A91023G","A91347G","T91489G","G92009A","A92102G","C92237T","C92516T","T93356C","T95469C","C95477A","A95795G","C96651T","G97572A","T98430G","A99212G","G99234A","A99683G","T99830C","A100261G","T100341C","T100562C","C102971A","A103051G","T103424G","C105126T","T106115C","A106857C","G107232A","C107394T","T107511G","A108793G","A109382G","G109580A","T110828G","T111539C","A111545G","A111591T","T111716C","G113747A","A114458G","T116583C","A116643T","G116660A","G117014A","T117725G","T118520C","C120174A","C120252T","T120363C","A120965G","A121082G","C121453A","A121711G","T122049C","G122422A","T124687C","T124737C","G124988C","G125047A","A125334G","A125556G","A126255G","T126923G","T126969C","T127859C","A128076G","T128546G","A130030G","T131806C","T132118C","A132719C","T133099C","T133145C","A133201G","T133280C","A133328G","A133455G","T133733C","T133966C","A134233T","A134491G","T134765C","A134884G","A135706G","T136190G","A136486C","A136498G","T136555C","G136558C","A136596G","A136604G","A136687G","A136870G","T137026G","T137377C","A137627G","T137731C","A137925G","T138513C","G138654A","T138746C","T139285G","T139539C","A139771G","T139874C","A141300G","T141364C","A142450C","A143108G","T143392C","T143426C","C143997T","T144049C","T145074C","T145088G","T145336C","T145523G","A145551C","A145803C","G146098T","A146215G","A146434G","C146446T","C146687T","T147860C","T147904G","G148126A","G149765T","G149878A","C150132T","G150153A","T150444C","T150488C","T150513C","A150545G","C150756T","A150780G","A151320G","C151341A","A151923G","T152967A","A153645G","A154405G","T154408C","C154702T","C154975T","C155479A","A155843G","T156426C","A156512G","A156954G","T156978C","G157273T","A157437G","T157490C","A158175C","A158398G","A158403G","A158511G","T158668G","T158787G","A159351G","A159415G","C159447A","T159530C","C159741T","A159780G","T160152C","A160867G","A160924T","A161519T","T161574C","A161799G","A162291G","C162639T","A162720G","T162828C","T163467C","T164848C","G165006A","T165304C","C165691T","T166399G","T166934C","C167126T","T167656G","T167858C","T168185C","A168277C","G168588C","C168769T","C168987A","A169081G","T169142C","A169353G","A169603G","T169721A","T170037C","A170248G","A170335G","A170435G","A171675G","T172087A","A172188G","A172304G","A172980G","A173102G","A173150G","T173441C","A173472G","C173569T","A173809G","T173810C","C173882T","A173974G","T174170C","G174301A","C175065A","C175964T","T176160C","C176453T","G176701A","G176715A","T177167G","T177517C","T177724C","T178237C","T178275C","A178311C","A178395G","A178423G","A178540G","G178639A","G178791A","G178887A","G179023A","C179226T","C179478T","A179538C","G179589T","T179690C","T180197C","A181350G","T181364A","A181994G","T182033C","A182348C","A182443G","A182491G","T183008C","A183491G","A183695G","T183696C","T183718C","T183920C","A184137G","T184286C","G185268A","A185762G","T185900C","T186077C","T186466G","A186505G","T187080A","T187345C","C187421T","A187498G","T187839C","G187914A","T187964C","A188096C","T188537C","G188726A","A188747C","A188812G","T189179A","A189418G","T189811G","A189909C","T190098G","G190154A","A190396T","G190404T","T190596G","A190648T","C190772A","A191051G","T191064C","G191401A","C191459T","A192374C","C192471T","C192519T","T193760C","T193790C","A194111C","G194819T","A195124C","A195396C","T195397G","T195523C","T195706C","G196009A","T196117C","A196490G","A196744G"],"OPG002":["A121S","N313T"],"OPG002_dup":["A121S","N313T"],"OPG005":["N74D"],"OPG015":["V4A","L136F"],"OPG015_dup":["V4A","L136F"],"OPG016":["S63A","E80V","D121E"],"OPG019":["M124R"],"OPG021":["V38I","K230R"],"OPG022":["G73D"],"OPG023":["V174A","A193S","Y300H","V426A","T488A","K637E"],"OPG024":["S32G"],"OPG025":["E393K","I425V"],"OPG029":["C146R"],"OPG030":["N12D","S113N"],"OPG031":["D117E","M271K"],"OPG034":["L205R"],"OPG036":["S11P","D25E"],"OPG037":["C415R"],"OPG038":["H27P","V78I"],"OPG040":["P254A","Y374S"],"OPG043":["T3A"],"OPG044":["M148L"],"OPG045":["A185T"],"OPG046":["S95N"],"OPG047":["I232K"],"OPG049":["E17V","M37V","T263M"],"OPG054":["R438G"],"OPG056":["V323A","C622Y"],"OPG059":["I26L"],"OPG063":["V307A"],"OPG064":["A88S"],"OPG065":["N23D"],"OPG066":["K83R","H97N"],"OPG068":["D341E"],"OPG071":["L411W","I428T","A484S","I501V"],"OPG074":["N199D","I441V"],"OPG079":["C45Y"],"OPG080":["D321E","C382S"],"OPG084":["S211T","Q620R"],"OPG085":["T328A","F591V"],"OPG094":["R175T"],"OPG096":["I68M"],"OPG100":["K152Q"],"OPG101":["T153A"],"OPG102":["I249V"],"OPG104":["T12A"],"OPG105":["V113G","I1070V"],"OPG108":["V4A"],"OPG109":["A622T"],"OPG111":["I77V"],"OPG112":["H34R"],"OPG118":["K256R","N413S","V462A","K606E"],"OPG125":["I514V"],"OPG130":["T63A","T122A"],"OPG135":["V90E"],"OPG145":["I264T","A348P","Q463R"],"OPG148":["I313S"],"OPG150":["N100D","D256E"],"OPG153":["M14T","I355T","Y358H","I370M","I371M","Q493P"],"OPG154":["H107R"],"OPG156":["Y42S","T222A"],"OPG157":["M24V"],"OPG159":["T2A","L36S"],"OPG161":["K67E","V88A"],"OPG164":["I111V","Y217H"],"OPG165":["S161L"],"OPG167":["Y107S","I112V"],"OPG170":["G31D","M111I"],"OPG172":["M145T","Y160D"],"OPG176":["D24N","L227S"],"OPG178":["I139V"],"OPG185":["T167A","D177E","I205T"],"OPG187":["K300*"],"OPG189":["C506R"],"OPG191":["F80C"],"OPG193":["I108R"],"OPG195":["C120S"],"OPG197":["S18T"],"OPG198":["N71D","I100V","Q133R"],"OPG199":["K230E"],"OPG200":["D52G"],"OPG204":["N178K"],"OPG205":["W169R","C349Y","G354S","V621A","V690A"],"OPG208":["I142T","V311A"],"OPG210":["F3L","K331N","H363R","D379G","S781P","V788A","T928A","A1305T","L1704R","D1717G"]},"labels":{"aa":"OPG002: A121S, N313T; OPG002_dup: A121S, N313T; OPG005: N74D; OPG015: V4A, L136F; OPG015_dup: V4A, L136F; OPG016: S63A, E80V, D121E; OPG019: M124R; OPG021: V38I, K230R; OPG022: G73D; OPG023: V174A, A193S, Y300H, V426A, T488A, K637E; OPG024: S32G; OPG025: E393K, I425V; OPG029: C146R; OPG030: N12D, S113N; OPG031: D117E, M271K; OPG034: L205R; OPG036: S11P, D25E; OPG037: C415R; OPG038: H27P, V78I; OPG040: P254A, Y374S; OPG043: T3A; OPG044: M148L; OPG045: A185T; OPG046: S95N; OPG047: I232K; OPG049: E17V, M37V, T263M; OPG054: R438G; OPG056: V323A, C622Y; OPG059: I26L; OPG063: V307A; OPG064: A88S; OPG065: N23D; OPG066: K83R, H97N; OPG068: D341E; OPG071: L411W, I428T, A484S, I501V; OPG074: N199D, I441V; OPG079: C45Y; OPG080: D321E, C382S; OPG084: S211T, Q620R; OPG085: T328A, F591V; OPG094: R175T; OPG096: I68M; OPG100: K152Q; OPG101: T153A; OPG102: I249V; OPG104: T12A; OPG105: V113G, I1070V; OPG108: V4A; OPG109: A622T; OPG111: I77V; OPG112: H34R; OPG118: K256R, N413S, V462A, K606E; OPG125: I514V; OPG130: T63A, T122A; OPG135: V90E; OPG145: I264T, A348P, Q463R; OPG148: I313S; OPG150: N100D, D256E; OPG153: M14T, I355T, Y358H, I370M, I371M, Q493P; OPG154: H107R; OPG156: Y42S, T222A; OPG157: M24V; OPG159: T2A, L36S; OPG161: K67E, V88A; OPG164: I111V, Y217H; OPG165: S161L; OPG167: Y107S, I112V; OPG170: G31D, M111I; OPG172: M145T, Y160D; OPG176: D24N, L227S; OPG178: I139V; OPG185: T167A, D177E, I205T; OPG187: K300*; OPG189: C506R; OPG191: F80C; OPG193: I108R; OPG195: C120S; OPG197: S18T; OPG198: N71D, I100V, Q133R; OPG199: K230E; OPG200: D52G; OPG204: N178K; OPG205: W169R, C349Y, G354S, V621A, V690A; OPG208: I142T, V311A; OPG210: F3L, K331N, H363R, D379G, S781P, V788A, T928A, A1305T, L1704R, D1717G","clade":"outgroup"}},"children":[{"name":"reconstructed_ancestral_mpox","node_attrs":{"div":0,"clade_membership":{"value":"outgroup"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000001","node_attrs":{"div":9,"clade_membership":{"value":"outgroup"}},"branch_attrs":{"mutations":{"nuc":["T607-","T608-","T609-","T4694-","T4695-","T6429C","A6430T","T6978-","A8055-","T8499-","T8993-","A16608-","G23171-","A23172T","G23173A","A23175G","A23176C","C29758T","A32210-","C32211-","G32212-","A33199-","T33414-","A39072T","T132813-","T133090-","T133091-","T133092-","T133093-","T133094-","T133095-","T133096-","T133097-","T133098-","C133099-","T133100-","T133101-","T133102-","T133177-","T133179-","T133180-","T133181-","T133183-","A133185-","A133186-","C136555-","C136558-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","A156415-","A156548-","A157678-","A157679-","A157680-","A157681-","T157682-","T157683-","T157684-","T157685-","A157686-","A157687-","A157691-","T157692-","A157694-","T157695-","A157696-","A158027-","T158028-","A158029-","A158170-","T166656-","T166657-","A169721-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","A173501-","T173502-","T173745-","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","T179226C","A181114-","T181115-","T181116-","T181119-","T181120-","A181121-","T181122-","A187080-","A189179T","T189744-","T190396A","T192471-","A192515-","A192516-","A196615-","A196616-","A196617-"],"OPG049":["R314-"],"OPG153":["M370I","M371I"],"OPG159":["N124-","Y125-","N126-"],"OPG191":["F166-"]},"labels":{"aa":"OPG049: R314-; OPG153: M370I, M371I; OPG159: N124-, Y125-, N126-; OPG191: F166-"}},"children":[{"name":"NODE_0000002","node_attrs":{"div":262,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G475A","T600-","T601-","T602-","T603-","T604-","T605-","T606-","G749A","A1309G","G2239-","A2240-","C2241-","C2659T","C3143T","G4042A","C4693-","A4696-","A4697-","C4698-","T4699-","A4700-","A4701-","C4702-","T4703-","T4704-","A4705-","T4706-","G4707-","A4708-","C4709-","T4710-","T4711-","A4712-","A4713-","C4714-","T4715-","A4716-","A4717-","C4718-","T4719-","T4720-","A4721-","T4722-","G4723-","A4724-","C4725-","T4726-","T4727-","A4728-","A4729-","C4730-","T4731-","A4732-","A4733-","C4734-","T4735-","T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","A4748-","A4749-","C4750-","T4751-","T4752-","A4753-","T4754-","G4755-","A4756-","C4757-","T4758-","T4759-","A4760-","A4761-","C4762-","T4763-","A4764-","A4765-","C4766-","T4767-","T4768-","A4769-","T4770-","G4771-","A4772-","C4773-","T4774-","T4775-","C5809T","T6159C","T6432-","C6433-","-6976T","-6978C","G7021-","C7022-","T7023-","C7024-","T7025-","C7026-","C7148-","T7149-","A7150-","T7151-","G7205A","T7405-","T7411C","G8277A","T8328-","T8329-","A8421-","C8422-","A8423-","T8424-","A8471-","C8603A","A8810G","A8830G","T8919-","G9139A","A9282-","C9404T","A9529-","C10242T","A11097T","C11625T","A11991G","G12128A","C12574A","A13276-","T13353-","C14647T","T15281C","A15549-","T15550-","A15657T","A15872-","C15883A","C16002T","G16102A","T16239C","T16609-","C16610-","A16611-","T16612-","C16613-","G17525A","A18055-","C18056-","C18057-","C18107T","G18590A","A19086G","T19282G","C22003T","C23283T","C23648T","A24310-","C24338-","A25528T","G25777A","C27692T","T28278C","A28415G","A28590-","G28591-","T28592-","G28593-","T28594-","T28595-","A28596-","A28597-","A28598-","A28599-","A28600-","A28601-","A28602-","T28603-","T28604-","A28605-","T28606-","C28607-","C28608-","T29029C","G29923A","C30730T","C31081T","C31529T","G31955A","C33159T","C35352A","G36445A","T39076-","G40501A","A41207G","C41735T","A41861G","T41935-","C44387T","G44966A","G46303T","G46421A","C46435T","A46506-","C46507-","A46508-","T46583G","T46596-","G46610A","T46648-","T46760C","A47576-","A47700-","C47701-","G47966A","C48041T","G48062T","A48166-","G48167-","T48168-","C48392T","C48951T","C49139T","G49859T","C49957T","C50500-","T50501-","T50575-","A50576-","C51202T","G53269T","G54352T","G54497A","T57433C","C57572T","G57622A","A58872G","T59648C","G60274T","A60457G","G60753A","G62250A","C62649T","T66650C","G67611A","A68297T","A68795G","C69896T","C70774A","C71035T","A71205G","G71553A","G71587A","A72217T","C72231T","C73350T","T82688C","T84290C","C84927T","A86247G","G86728A","C87560T","T88356A","G88746A","A89276G","C90820T","G93339A","C94061T","G94623A","G95280A","C97134A","G97408A","G98202A","A98856G","G100445A","T101536C","C101694T","C103006A","C103764T","C103805A","C104134T","A104556G","C104840T","G106554A","G107118C","C107322A","G107764A","G109874A","G111095T","A111303G","G111715A","G112206A","A112221G","C112455T","A113916G","G113924A","T114770C","C115676T","A116427C","T116735C","C117047T","G118640A","A118740T","C118789T","C118903T","G119474A","G123382A","A124691G","C124714A","A125365G","G126603A","T127137C","A128940T","A129767G","C131809T","G132286A","G132887A","T133084C","T133088-","T133089-","C133178-","C133182-","C133184-","T133224C","G133368A","T133493-","C133494-","G133495-","G133496-","T133497-","C133498-","C133499-","A133500-","T133501-","G133502-","T133503-","C133504-","T133505-","C133506-","C133507-","A133508-","T133509-","T133510-","G133511-","C133512-","T133513-","A133514-","C133515-","A133516-","C133517-","C133518-","A133519-","C133520-","C133521-","A133522-","T133523-","T133524-","A133525-","G133526-","A133527-","T133528-","T133529-","T133530-","A133531-","C133532-","A133533-","G133534-","G133535-","C133536-","T133537-","G133538-","C133539-","T133540-","A133541-","G133542-","T133543-","T133544-","G133545-","T133546-","C133547-","G133548-","T133549-","T133550-","C133551-","G133552-","A133553-","G133554-","A133555-","T133556-","C133557-","A133558-","G133559-","A133560-","A133561-","A133562-","T133563-","A133564-","C133565-","G133566-","T133567-","G133568-","T133569-","T133570-","T133571-","T133572-","C133573-","T133574-","T133575-","G133576-","G133577-","A133578-","A133579-","T133580-","G133581-","G133582-","A133583-","T133584-","T133585-","T133586-","C133587-","G133588-","T133589-","C133590-","G133591-","A133592-","T133593-","G133594-","T133595-","A133596-","C133597-","T133598-","T133599-","G133600-","T133601-","C133602-","A133603-","T133604-","G133605-","A133606-","T133607-","T133608-","G133609-","G133610-","C133611-","A133612-","T133613-","C133614-","G133615-","A133616-","A133617-","A133618-","C133619-","A133620-","C133621-","T133622-","T133623-","A133624-","T133625-","T133626-","A133627-","A133628-","G133629-","T133630-","T133631-","C133632-","T133633-","T133634-","T133635-","T133636-","T133637-","T133638-","T133639-","C133640-","A133641-","A133642-","T133643-","T133644-","C133645-","T133646-","A133647-","C133648-","G133649-","A133650-","T133651-","T133652-","T133653-","T133654-","A133655-","T133656-","T133657-","T133658-","C133659-","T133660-","T133661-","T133662-","C133663-","G133664-","C133665-","G133666-","A133667-","G133668-","T133669-","C133670-","A133671-","A133672-","T133673-","T133674-","C133675-","C133676-","C133677-","T133678-","C133679-","C133680-","T133681-","G133682-","T133683-","A133684-","G133685-","T133686-","A133687-","A133688-","C133689-","T133690-","A133691-","T133692-","C133693-","A133694-","G133695-","T133696-","T133697-","T133698-","T133699-","G133700-","T133701-","C133702-","A133703-","G133704-","A133705-","T133706-","T133707-","C133708-","A133709-","C133710-","G133711-","C133712-","T133713-","C133714-","T133715-","C133716-","T133717-","A133718-","C133719-","G133720-","T133721-","A133722-","G133723-","A133724-","C133725-","T133726-","T133727-","T133728-","C133729-","T133730-","T133731-","G133732-","C133733-","A133734-","A133735-","G133736-","T133737-","T133738-","A133739-","C133740-","T133741-","A133742-","A133743-","T133744-","T133745-","T133746-","G133747-","T133748-","T133749-","C133750-","C133751-","C133752-","T133753-","G133754-","G133755-","C133756-","A133757-","T133758-","T133759-","A133760-","C133761-","C133762-","G133763-","A133764-","G133765-","T133766-","T133767-","C133768-","A133769-","G133770-","T133771-","T133772-","T133773-","T133774-","A133775-","T133776-","A133777-","T133778-","G133779-","C133780-","C133781-","G133782-","A133783-","A133784-","T133785-","A133786-","G133787-","A133788-","G133789-","T133790-","T133791-","C133792-","T133793-","G133794-","A133795-","T133796-","T133797-","C133798-","A133799-","T133800-","C133801-","C133802-","T133803-","T133804-","T133805-","G133806-","A133807-","G133808-","A133809-","A133810-","G133811-","A133812-","T133813-","C133814-","T133815-","C133816-","T133817-","A133818-","G133819-","C133820-","G133821-","A133822-","T133823-","C133824-","G133825-","T133826-","T133827-","C133828-","A133829-","A133830-","G133831-","A133832-","T133833-","C133834-","C133835-","C133836-","T133837-","G133838-","A133839-","T133840-","T133841-","C133842-","T133843-","A133844-","G133845-","T133846-","C133847-","T133848-","T133849-","T133850-","A133851-","G133852-","C133853-","C133854-","T133855-","A133856-","T133857-","T133858-","T133859-","A133860-","C133861-","C133862-","T133863-","C133864-","C133865-","T133866-","C133867-","A133868-","G133869-","A133870-","A133871-","G133872-","A133873-","T133874-","G133875-","C133876-","T133877-","C133878-","C133879-","G133880-","T133881-","T133882-","A133883-","C133884-","C133885-","G133886-","T133887-","T133888-","T133889-","T133890-","T133891-","A133892-","C133893-","A133894-","A133895-","T133896-","C133897-","G133898-","T133899-","T133900-","A133901-","A133902-","G133903-","A133904-","T133905-","G133906-","T133907-","C133908-","T133909-","A133910-","T133911-","C133912-","A133913-","A133914-","G133915-","A133916-","T133917-","C133918-","C133919-","A133920-","T133921-","G133922-","A133923-","T133924-","T133925-","C133926-","T133927-","A133928-","T133929-","C133930-","T133931-","C133932-","T133933-","T133934-","T133935-","T133936-","C133937-","C133938-","A133939-","T133940-","A133941-","T133942-","C133943-","A133944-","G133945-","C134152T","G134354T","A135987T","G136015A","C136390A","-136555T","-136558G","A136864C","C137830T","T138627C","G138840T","T139429-","T139430-","G139431-","G141071A","A141497G","G141759A","G142056A","C142159T","T142338C","A142755-","G143459-","T143743G","G143831A","C144025T","G144742A","C145303T","G145642T","A145892-","G145908A","T145979-","A145980-","A145981-","C146084-","G146085-","C146395A","G146494A","G146632T","A146863-","T146864-","T146884-","T146885-","T146886-","A146887-","T146888-","A146889-","T146890-","T146891-","T146892-","T146893-","A146894-","T146895-","A146969-","C147489T","G147780A","C147800T","A148336-","T148344A","A150156G","T150539-","A150549T","A150968T","G151022-","A151023-","C151024-","A151025-","T151026-","A151043-","T151289G","A152267-","T152268-","T152269-","G152328A","G154263A","C154354-","T154355-","C154389T","T154664A","C154791A","T155424-","C155483A","G155888A","A156210-","T156371-","A156372-","C156373-","T156374-","G156375-","A156376-","C156377-","T156378-","A156379-","C156380-","A156381-","T156382-","G156383-","T156384-","A156385-","C156386-","T156387-","A156388-","T156389-","T156390-","T156391-","T156392-","A156393-","C156394-","A156395-","T156396-","T156397-","A156398-","C156399-","T156400-","A156401-","C156402-","A156403-","T156404-","T156405-","G156406-","G156407-","C156408-","T156409-","A156410-","C156411-","G156412-","G156413-","C156414-","T156416-","A156417-","T156418-","A156419-","T156420-","A156421-","C156422-","C156423-","T156424-","A156425-","C156426-","T156427-","T156428-","C156429-","G156430-","T156431-","C156432-","A156433-","C156434-","T156435-","T156436-","C156437-","C156438-","A156439-","C156440-","A156441-","C156442-","G156443-","C156444-","T156445-","C156446-","C156447-","G156448-","G156449-","T156450-","A156451-","A156452-","A156453-","C156454-","G156455-","G156456-","G156457-","T156458-","G156459-","T156460-","C156461-","A156462-","T156463-","G156464-","T156465-","G156466-","A156467-","C156468-","G156469-","A156470-","G156471-","G156472-","G156473-","A156474-","G156475-","A156476-","A156477-","T156478-","C156479-","T156480-","T156481-","G156482-","A156483-","T156484-","A156485-","A156486-","G156487-","A156488-","G156489-","G156490-","C156491-","A156492-","T156493-","A156494-","A156495-","T156496-","C156497-","A156498-","A156499-","T156500-","G156501-","T156502-","T156503-","G156504-","T156505-","A156506-","A156507-","T156508-","C156509-","C156510-","G156511-","G156512-","T156513-","G156514-","T156515-","C156516-","C156517-","A156518-","C156519-","C156520-","T156521-","G156522-","G156523-","A156524-","G156525-","A156526-","A156527-","T156528-","T156529-","T156530-","G156531-","C156532-","C156533-","A156534-","A156535-","G156536-","G156537-","T156538-","C156539-","A156540-","G156541-","A156542-","T156543-","G156544-","T156545-","A156546-","G156547-","G156549-","T156550-","T156551-","G156552-","G156553-","T156554-","A156555-","G156556-","T156557-","G156558-","A156559-","T156560-","A156561-","A156562-","C156563-","A156564-","C156565-","A156566-","A156567-","A156568-","A156569-","T156570-","G156571-","T156572-","G156573-","A156574-","A156575-","C156576-","A156577-","C156578-","T156579-","G156580-","C156581-","C156582-","C156583-","A156584-","C156585-","C156586-","T156587-","C156588-","A156589-","T156590-","A156591-","C156592-","A156593-","T156594-","A156595-","T156596-","A156597-","C156598-","C156599-","G156600-","C156601-","A156602-","A156603-","T156604-","C156605-","C156606-","C156607-","C156608-","A156609-","A156610-","T156611-","T156612-","A156613-","T156614-","T156615-","C156616-","T156617-","A156618-","A156619-","T156620-","A156621-","G156622-","A156623-","T156624-","G156625-","T156626-","C156627-","A156628-","T156629-","C156630-","A156631-","A156632-","T156633-","G156634-","T156635-","A156636-","G156637-","A156638-","A156639-","A156640-","A156641-","T156642-","G156643-","C156644-","C156645-","C156646-","A156647-","A156648-","C156649-","A156650-","G156651-","G156652-","A156653-","T156654-","C156655-","A156656-","T156657-","T156658-","T156659-","G156660-","A156661-","T156662-","A156663-","A156664-","G156665-","G156666-","T156667-","A156668-","A156669-","A156670-","G156671-","T156672-","G156673-","T156674-","A156675-","C156676-","C156677-","G156678-","G156679-","A156680-","A156681-","C156682-","A156683-","C156684-","A156685-","G156686-","A156687-","A156688-","C156689-","A156690-","A156691-","A156692-","T156693-","G156694-","T156695-","T156696-","C156697-","G156698-","T156699-","G156700-","T156701-","C156702-","A156703-","T156704-","C156705-","C156706-","T156707-","G156708-","G156709-","T156710-","T156711-","G156712-","G156713-","T156714-","A156715-","T156716-","A156717-","C156718-","G156719-","C156720-","T156721-","A156722-","C156723-","T156724-","G156725-","A156726-","T156727-","T156728-","C156729-","T156730-","T156731-","C156732-","A156733-","C156734-","A156735-","G156736-","A156737-","C156738-","T156739-","G156740-","A156741-","A156742-","G156743-","A156744-","T156745-","T156746-","G156747-","T156748-","C156749-","G156750-","A156751-","G156752-","A156753-","T156754-","T156755-","T156756-","G156757-","T156758-","G156759-","T156760-","A156761-","C156762-","C156763-","A156764-","A156765-","A156766-","A156767-","A156768-","A156769-","G156770-","G156771-","A156772-","G156773-","A156774-","T156775-","G156776-","T156777-","C156778-","C156779-","A156780-","T156781-","G156782-","C156783-","G156784-","G156785-","A156786-","T156787-","A156788-","C156789-","T156790-","T156791-","T156792-","G156793-","G156794-","T156795-","G156796-","G156797-","A156798-","A156799-","T156800-","A156801-","G156802-","A156803-","T156804-","G156805-","A156806-","A156807-","G156808-","G156809-","A156810-","A156811-","A156812-","T156813-","C156814-","C156815-","T156816-","A156817-","T156818-","T156819-","T156820-","G156821-","T156822-","A156823-","A156824-","A156825-","T156826-","C156827-","G156828-","T156829-","G156830-","T156831-","T156832-","G156833-","T156834-","G156835-","T156836-","T156837-","G156838-","G156839-","T156840-","G156841-","A156842-","A156843-","T156844-","A156845-","T156846-","T156847-","G156848-","C156849-","G156850-","A156851-","C156852-","T156853-","A156854-","C156855-","C156856-","T156857-","A156858-","C156859-","G156860-","T156861-","A156862-","A156863-","T156864-","T156865-","A156866-","T156867-","A156868-","G156869-","A156870-","C156871-","T156872-","T156873-","G156874-","A156875-","T156876-","C156877-","C156878-","A156879-","T156880-","T156881-","T156882-","C156883-","C156884-","T156885-","C156886-","C156887-","A156888-","T156889-","G156890-","C156891-","A156892-","A156893-","A156894-","C156895-","T156896-","A156897-","T156898-","C156899-","T156900-","A156901-","T156902-","C156903-","T156904-","A156905-","A156906-","A156907-","T156908-","G156909-","T156910-","A156911-","A156912-","T156913-","T156914-","A156915-","A156916-","T156917-","T156918-","A156919-","T156920-","G156921-","A156922-","T156923-","T156924-","T156925-","T156926-","G156927-","A156928-","T156929-","G156930-","A156931-","T156932-","A156933-","A156934-","T156935-","G156936-","T156937-","T156938-","A156939-","C156940-","C156941-","A156942-","T156943-","A156944-","C156945-","A156946-","T156947-","T156948-","A156949-","T156950-","A156951-","T156952-","C156953-","G156954-","C156955-","T156956-","A156957-","C156958-","T156959-","T156960-","G156961-","G156962-","T156963-","T156964-","A156965-","G156966-","T156967-","G156968-","T156969-","G156970-","T156971-","A156972-","T156973-","T156974-","A156975-","T156976-","T156977-","C156978-","A156979-","G156980-","T156981-","A156982-","T156983-","G156984-","G156985-","A156986-","A156987-","G156988-","A156989-","C156990-","C156991-","T156992-","A156993-","T156994-","T156995-","A156996-","A156997-","T156998-","A156999-","A157000-","T157001-","T157002-","A157003-","C157004-","T157005-","T157006-","A157007-","T157008-","C157009-","T157010-","T157011-","T157012-","T157013-","G157014-","A157015-","C157016-","G157017-","A157018-","T157019-","C157020-","T157021-","T157022-","G157023-","T157024-","T157025-","A157026-","T157027-","A157028-","A157029-","T157030-","T157031-","A157032-","T157033-","A157034-","A157035-","T157036-","A157037-","T157038-","A157039-","A157040-","A157041-","A157042-","A157043-","T157044-","A157045-","C157046-","T157047-","T157048-","A157049-","T157050-","G157051-","A157052-","C157053-","A157054-","T157055-","A157056-","G157057-","T157058-","A157059-","A157060-","C157061-","T157062-","C157063-","A157064-","T157065-","A157066-","A157067-","T157068-","T157069-","G157070-","C157071-","T157072-","G157073-","A157074-","C157075-","G157076-","C157077-","G157078-","A157079-","T157080-","A157081-","A157082-","A157083-","T157084-","T157085-","C157086-","G157087-","T157088-","A157089-","A157090-","T157091-","A157092-","A157093-","T157094-","C157095-","T157096-","G157097-","T157098-","T157099-","T157100-","T157101-","G157102-","T157103-","T157104-","C157105-","A157106-","A157107-","A157108-","T157109-","T157110-","T157111-","T157112-","T157113-","A157114-","T157115-","A157116-","A157117-","G157118-","G157119-","A157120-","A157121-","T157122-","C157123-","T157124-","A157125-","C157126-","A157127-","G157128-","G157129-","C157130-","A157131-","T157132-","A157133-","A157134-","A157135-","A157136-","A157137-","T157138-","A157139-","A157140-","A157141-","A157142-","A157143-","T157144-","A157145-","T157146-","A157147-","A157148-","T157149-","C157150-","T157151-","A157152-","T157153-","A157154-","A157155-","T157156-","A157157-","T157158-","A157159-","C157160-","T157161-","C157162-","T157163-","T157164-","A157165-","C157166-","A157167-","A157168-","C157169-","G157170-","C157171-","C157172-","A157173-","T157174-","C157175-","A157176-","T157177-","G157178-","A157179-","A157180-","T157181-","A157182-","G157183-","C157184-","A157185-","G157186-","T157187-","G157188-","A157189-","A157190-","T157191-","T157192-","A157193-","A157194-","T157195-","T157196-","G157197-","C157198-","T157199-","G157200-","T157201-","T157202-","A157203-","T157204-","T157205-","A157206-","T157207-","G157208-","G157209-","A157210-","T157211-","T157212-","T157213-","A157214-","G157215-","A157216-","A157217-","A157218-","T157219-","A157220-","G157221-","T157222-","G157223-","G157224-","A157225-","C157226-","G157227-","A157228-","T157229-","T157230-","T157231-","T157232-","G157233-","T157234-","G157235-","A157236-","T157237-","A157238-","T157239-","T157240-","A157241-","A157242-","T157243-","A157244-","T157245-","A157246-","G157247-","T157248-","T157249-","A157250-","T157251-","T157252-","A157253-","A157254-","T157255-","G157256-","A157257-","T157258-","G157259-","A157260-","A157261-","A157262-","G157263-","G157264-","A157265-","T157266-","A157267-","A157268-","A157269-","C157270-","G157271-","C157272-","T157273-","C157274-","A157275-","T157276-","A157277-","G157278-","A157279-","C157280-","T157281-","C157282-","A157283-","T157284-","C157285-","C157286-","T157287-","A157288-","T157289-","C157290-","T157291-","G157292-","G157293-","A157294-","G157295-","C157296-","C157297-","T157298-","C157299-","C157300-","G157301-","A157302-","A157303-","T157304-","A157305-","T157306-","T157307-","T157308-","T157309-","T157310-","T157311-","C157312-","C157313-","A157314-","T157315-","T157316-","C157317-","T157318-","G157319-","T157320-","T157321-","T157322-","T157323-","C157324-","C157325-","A157326-","A157327-","T157328-","A157329-","A157330-","T157331-","T157332-","T157333-","T157334-","A157335-","T157336-","C157337-","G157338-","A157339-","T157340-","T157341-","C157342-","T157343-","A157344-","A157345-","T157346-","G157347-","A157348-","A157349-","T157350-","A157351-","C157352-","G157353-","A157354-","A157355-","G157356-","T157357-","T157358-","A157359-","A157360-","T157361-","C157362-","T157363-","A157364-","A157365-","G157366-","T157367-","C157368-","A157369-","T157370-","T157371-","T157372-","A157373-","G157374-","A157375-","T157376-","T157377-","A157378-","T157379-","C157380-","A157381-","A157382-","A157383-","G157384-","T157385-","G157386-","T157387-","T157388-","A157389-","A157390-","C157391-","T157392-","A157393-","T157394-","T157395-","T157396-","G157397-","A157398-","T157399-","C157400-","G157401-","A157402-","T157403-","T157404-","A157405-","C157406-","A157407-","T157408-","T157409-","T157410-","A157411-","T157412-","G157413-","G157414-","G157415-","A157416-","T157417-","A157418-","C157419-","C157420-","T157421-","T157422-","T157423-","G157424-","A157425-","G157426-","C157427-","C157428-","T157429-","A157430-","A157431-","C157432-","T157433-","A157434-","A157435-","C157436-","G157437-","A157438-","T157439-","A157440-","A157441-","C157442-","G157443-","T157444-","G157445-","A157446-","A157447-","A157448-","T157449-","A157450-","T157451-","A157452-","T157453-","T157454-","C157455-","T157456-","T157457-","T157458-","C157459-","A157460-","A157461-","C157462-","C157463-","G157464-","C157465-","T157466-","G157467-","A157468-","T157469-","T157470-","T157471-","T157472-","T157473-","T157474-","T157475-","A157476-","C157477-","A157478-","A157479-","A157480-","T157481-","T157482-","G157483-","G157484-","A157485-","T157486-","C157487-","T157488-","G157489-","C157490-","C157491-","A157492-","T157493-","T157494-","A157495-","C157496-","T157497-","G157498-","A157499-","G157500-","T157501-","G157502-","C157503-","G157504-","A157505-","A157506-","A157507-","A157508-","A157509-","T157510-","A157511-","C157512-","A157513-","T157514-","A157515-","C157516-","T157517-","T157518-","A157519-","A157520-","A157521-","A157522-","A157523-","T157524-","C157525-","T157526-","T157527-","T157528-","G157529-","T157530-","T157531-","T157532-","T157533-","A157534-","G157535-","A157536-","A157537-","A157538-","C157539-","T157540-","G157541-","T157542-","A157543-","T157544-","C157545-","G157546-","A157547-","T157548-","T157549-","T157550-","C157551-","T157552-","A157553-","C157554-","A157555-","T157556-","A157557-","T157558-","A157559-","C157560-","G157561-","C157562-","T157563-","G157564-","A157565-","T157566-","A157567-","A157568-","A157569-","T157570-","A157571-","T157572-","A157573-","A157574-","T157575-","A157576-","A157577-","C157578-","A157579-","A157580-","G157581-","A157582-","A157583-","A157584-","A157585-","T157586-","A157587-","G157588-","A157589-","A157590-","T157591-","T157592-","A157593-","G157594-","C157595-","A157596-","T157597-","C157598-","G157599-","T157600-","T157601-","T157602-","A157603-","A157604-","C157605-","A157606-","C157607-","A157608-","A157609-","T157610-","A157611-","T157612-","T157613-","A157614-","C157615-","G157616-","A157617-","A157618-","A157619-","T157620-","A157621-","T157622-","T157623-","T157624-","T157625-","G157626-","A157627-","G157628-","A157629-","C157630-","T157631-","C157632-","A157633-","T157634-","C157635-","A157636-","A157637-","C157638-","A157639-","A157640-","T157641-","G157642-","A157643-","A157644-","A157645-","A157646-","C157647-","T157648-","T157649-","T157650-","A157651-","A157652-","A157653-","T157654-","A157655-","C157656-","T157657-","T157658-","A157659-","A157660-","C157661-","A157662-","G157663-","A157664-","G157665-","G157666-","A157667-","A157668-","T157669-","C157670-","A157671-","A157672-","T157673-","G157674-","A157675-","T157676-","A157677-","G157688-","C157689-","G157690-","G157693-","T157697-","G157698-","T157699-","T157700-","A157701-","T157702-","A157703-","T157704-","A157705-","T157706-","A157707-","A157708-","A157709-","A157710-","A157711-","A157712-","T157713-","G157714-","A157715-","G157716-","G157717-","A157718-","T157719-","T157720-","T157721-","C157722-","A157723-","C157724-","C157725-","C157726-","C157727-","A157728-","C157729-","T157730-","G157731-","A157732-","T157733-","T157734-","C157735-","T157736-","C157737-","A157738-","T157739-","T157740-","A157741-","A157742-","A157743-","T157744-","G157745-","G157746-","T157747-","T157748-","A157749-","G157750-","A157751-","G157752-","A157753-","G157754-","T157755-","A157756-","C157757-","A157758-","C157759-","C157760-","A157761-","A157762-","C157763-","C157764-","A157765-","T157766-","G157767-","T157768-","A157769-","C157770-","C157771-","G157772-","T157773-","C157774-","G157775-","A157776-","G157777-","T157778-","T157779-","A157780-","C157781-","T157782-","T157783-","A157784-","G157785-","A157786-","T157787-","G157788-","C157789-","C157790-","T157791-","C157792-","A157793-","G157794-","A157795-","A157796-","T157797-","A157798-","T157799-","C157800-","A157801-","T157802-","T157803-","T157804-","C157805-","T157806-","T157807-","T157808-","C157809-","C157810-","C157811-","C157812-","A157813-","C157814-","A157815-","A157816-","G157817-","T157818-","T157819-","A157820-","T157821-","A157822-","A157823-","A157824-","A157825-","T157826-","C157827-","A157828-","C157829-","T157830-","T157831-","T157832-","A157833-","T157834-","A157835-","G157836-","T157837-","C157838-","A157839-","T157840-","C157841-","G157842-","A157843-","C157844-","T157845-","G157846-","G157847-","T157848-","T157849-","A157850-","G157851-","T157852-","T157853-","C157854-","A157855-","A157856-","T157857-","C157858-","T157859-","A157860-","C157861-","G157862-","A157863-","A157864-","T157865-","G157866-","T157867-","A157868-","T157869-","A157870-","A157871-","C157872-","A157873-","T157874-","T157875-","C157876-","T157877-","T157878-","A157879-","A157880-","A157881-","C157882-","A157883-","A157884-","T157885-","A157886-","T157887-","A157888-","G157889-","C157890-","A157891-","T157892-","T157893-","C157894-","T157895-","T157896-","G157897-","G157898-","A157899-","T157900-","A157901-","A157902-","A157903-","T157904-","C157905-","A157906-","T157907-","T157908-","T157909-","C157910-","C157911-","T157912-","A157913-","G157914-","A157915-","T157916-","A157917-","C157918-","C157919-","A157920-","T157921-","A157922-","T157923-","C157924-","A157925-","T157926-","C157927-","G157928-","A157929-","G157930-","T157931-","T157932-","G157933-","A157934-","T157935-","A157936-","T157937-","C157938-","T157939-","A157940-","T157941-","C157942-","G157943-","G157944-","T157945-","A157946-","T157947-","A157948-","A157949-","G157950-","T157951-","A157952-","A157953-","T157954-","T157955-","C157956-","A157957-","C157958-","A157959-","T157960-","G157961-","A157962-","T157963-","A157964-","A157965-","G157966-","A157967-","T157968-","T157969-","T157970-","C157971-","C157972-","A157973-","T157974-","A157975-","A157976-","A157977-","C157978-","T157979-","G157980-","C157981-","T157982-","A157983-","C157984-","A157985-","A157986-","T157987-","C157988-","A157989-","T157990-","A157991-","A157992-","A157993-","A157994-","A157995-","A157996-","A157997-","T157998-","T157999-","C158000-","A158001-","T158002-","G158003-","G158004-","G158005-","A158006-","A158007-","A158008-","T158009-","G158010-","A158011-","T158012-","A158013-","T158014-","C158015-","T158016-","T158017-","C158018-","A158019-","C158020-","G158021-","T158022-","A158023-","G158024-","A158025-","T158026-","G158030-","G158031-","T158032-","G158033-","T158034-","A158035-","G158036-","T158037-","T158038-","T158039-","C158040-","G158041-","C158042-","A158043-","G158044-","T158045-","G158046-","A158047-","C158048-","C158049-","G158050-","T158051-","C158052-","C158053-","T158054-","G158055-","G158056-","A158057-","T158058-","A158059-","A158060-","T158061-","A158062-","T158063-","T158064-","A158065-","T158066-","C158067-","T158068-","A158069-","T158070-","A158071-","T158072-","G158073-","A158074-","T158075-","G158076-","G158077-","G158078-","T158079-","G158080-","G158081-","A158082-","T158083-","A158084-","T158085-","G158086-","A158087-","T158088-","C158089-","A158090-","G158091-","T158092-","C158093-","C158094-","C158095-","T158096-","G158097-","T158098-","A158099-","T158100-","A158101-","G158102-","A158103-","A158104-","G158105-","T158106-","T158107-","C158108-","A158109-","A158110-","A158111-","G158112-","G158113-","T158114-","T158115-","A158116-","T158117-","A158118-","G158119-","C158120-","G158121-","T158122-","A158123-","C158124-","A158125-","A158126-","T158127-","A158128-","C158129-","A158130-","T158131-","G158132-","T158133-","A158134-","C158135-","T158136-","A158137-","A158138-","T158139-","T158140-","C158141-","T158142-","T158143-","G158144-","G158145-","A158146-","T158147-","A158148-","T158149-","A158150-","T158151-","G158152-","A158153-","T158154-","A158155-","T158156-","A158157-","C158158-","C158159-","A158160-","G158161-","A158162-","G158163-","C158164-","T158165-","A158166-","A158167-","A158168-","A158169-","T158171-","A158172-","T158173-","C158174-","C158175-","T158176-","C158177-","G158178-","T158179-","T158180-","C158181-","T158182-","A158183-","A158184-","T158185-","T158186-","G158187-","C158188-","G158189-","G158190-","A158191-","G158192-","G158193-","A158194-","G158195-","T158196-","T158197-","G158198-","C158199-","C158200-","A158201-","A158202-","T158203-","G158204-","A158205-","C158206-","G158207-","A158208-","A158209-","T158210-","A158211-","C158212-","A158213-","T158214-","T158215-","T158216-","A158217-","T158218-","T158219-","G158220-","T158221-","A158222-","T158223-","A158224-","G158225-","G158226-","C158227-","G158228-","G158229-","T158230-","A158231-","T158232-","A158233-","C158234-","G158235-","C158236-","G158237-","A158238-","T158239-","C158240-","A158241-","G158242-","G158243-","A158244-","G158245-","T158246-","C158247-","A158248-","T158249-","C158250-","G158251-","T158252-","T158253-","G158254-","A158255-","T158256-","A158257-","T158258-","C158259-","T158260-","A158261-","G158262-","T158263-","A158264-","T158265-","C158266-","G158267-","A158268-","T158269-","A158270-","G158271-","A158272-","T158273-","G158274-","G158275-","A158276-","A158277-","G158278-","C158279-","C158280-","A158281-","T158282-","C158283-","A158284-","A158285-","A158286-","A158287-","C158288-","C158289-","A158290-","T158291-","A158292-","T158293-","T158294-","G158295-","G158296-","C158297-","A158298-","G158299-","A158300-","A158301-","G158302-","T158303-","A158304-","T158305-","G158306-","C158307-","T158308-","A158309-","A158310-","A158311-","A158312-","T158313-","G158314-","T158315-","G158316-","C158317-","G158318-","A158319-","A158320-","C158321-","C158322-","A158323-","A158324-","A158325-","A158326-","T158327-","G158328-","T158329-","G158330-","A158331-","T158332-","A158333-","T158334-","G158335-","G158336-","G158337-","G158338-","T158339-","T158340-","G158341-","C158342-","G158343-","A158344-","T158345-","T158346-","T158347-","T158348-","A158349-","A158350-","A158351-","C158352-","G158353-","G158354-","A158355-","T158356-","T158357-","A158358-","A158359-","T158360-","A158361-","T158362-","A158363-","T158364-","G158365-","T158366-","C158367-","A158368-","T158369-","A158370-","G158371-","G158372-","T158373-","G158374-","G158375-","A158376-","G158377-","T158378-","C158379-","G158380-","T158381-","T158382-","A158383-","A158384-","A158385-","G158386-","G158387-","T158388-","G158389-","A158390-","C158391-","A158392-","C158393-","A158394-","C158395-","A158396-","T158397-","G158398-","T158399-","A158400-","C158401-","C158402-","G158403-","A158404-","C158405-","G158406-","C158407-","A158408-","C158409-","T158410-","A158411-","G158412-","A158413-","G158414-","A158415-","G158416-","T158417-","T158418-","T158419-","A158420-","T158421-","C158422-","A158423-","G158424-","A158425-","A158426-","G158427-","A158428-","T158429-","G158430-","G158431-","A158432-","T158433-","G158434-","G158435-","A158436-","T158437-","G158438-","A158439-","A158440-","T158441-","C158442-","A158443-","T158444-","C158445-","A158446-","A158447-","C158448-","G158449-","T158450-","C158451-","T158452-","T158453-","C158454-","C158455-","A158456-","A158457-","T158458-","A158459-","A158460-","A158461-","A158462-","A158463-","T158464-","G158465-","T158466-","C158467-","C158468-","A158469-","A158470-","T158471-","A158472-","T158473-","G158474-","T158475-","C158476-","G158477-","A158478-","C158479-","G158480-","A158481-","T158482-","T158483-","G158484-","T158485-","T158486-","C158487-","A158488-","T158489-","G158490-","C158491-","T158492-","G158493-","G158494-","A158495-","A158496-","A158497-","G158498-","A158499-","T158500-","T158501-","T158502-","A158503-","T158504-","A158505-","T158506-","A158507-","T158508-","C158509-","T158510-","G158511-","G158512-","A158513-","G158514-","G158515-","T158516-","T158517-","A158518-","C158519-","A158520-","A158521-","C158522-","A158523-","A158524-","T158525-","A158526-","G158527-","T158528-","A158529-","G158530-","T158531-","G158532-","T158533-","A158534-","G158535-","T158536-","T158537-","A158538-","A158539-","T158540-","G158541-","T158542-","A158543-","A158544-","T158545-","A158546-","T158547-","C158548-","G158549-","A158550-","A158551-","T158552-","C158553-","T158554-","A158555-","G158556-","T158557-","C158558-","C158559-","T158560-","T158561-","A158562-","G158563-","C158564-","T158565-","A158566-","T158567-","A158568-","A158569-","T158570-","C158571-","C158572-","G158573-","A158574-","T158575-","A158576-","T158577-","A158578-","T158579-","G158580-","A158581-","T158582-","G158583-","A158584-","A158585-","T158586-","G158587-","G158588-","A158589-","C158590-","C158591-","A158592-","A158593-","A158594-","T158595-","T158596-","A158597-","T158598-","C158599-","A158600-","T158601-","C158602-","A158603-","T158604-","T158605-","A158606-","A158607-","A158608-","T158609-","A158610-","T158611-","T158612-","C158613-","C158614-","T158615-","A158616-","G158617-","A158618-","A158619-","T158620-","T158621-","A158622-","A158623-","T158624-","C158625-","C158626-","T158627-","G158628-","C158629-","T158630-","C158631-","T158632-","A158633-","T158634-","T158751G","G160043-","C160057A","A160270G","C161356T","A161579G","T161591C","T162384C","G162388A","C162447T","T162852A","A163207-","A163208-","C163209-","T163210-","A163211-","A163212-","C163213-","T163214-","C163256T","A163886G","G164849A","C166006T","C166196T","C166309A","T166712-","G167029A","C168226T","C168466A","C169125T","G169672A","A169723-","A169725-","T169726-","T169792-","G170918-","C170999T","T172063-","A172550G","C172644T","C172671T","G173363T","G173436A","C173474T","A174044T","C174102A","C174146T","G174183T","G174537-","A174538-","T174539-","G174540-","A174541-","A174542-","T174855C","G177853A","A178328-","C178702T","C179366T","A180163G","T180435A","A180548G","C180578T","C181117-","C181118-","T181233C","C181351T","C181648A","A181790G","G181872A","A182356T","T182899C","C183555-","T183556-","A183557-","T184979C","C186840T","-187080T","G187145A","T187207-","C187533A","T187775-","G187896T","A188871G","C189206T","C189609T","A189896G","A190198-","C190199-","A190402-","T191134C","A192435-","A192436-","G192437-","T192438-","C192439-","A192440-","T192441-","A192442-","A192443-","G192444-","T192445-","T192446-","A192447-","G192448-","T192449-","T192450-","A192451-","A192452-","G192453-","T192454-","C192455-","A192456-","T192457-","A192458-","A192459-","G192460-","T192461-","T192462-","A192463-","G192464-","T192465-","T192466-","A192467-","A192468-","G192469-","T192470-","A192472-","T192473-","A192474-","A192475-","G192476-","T192477-","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-","A192490-","A192491-","G192492-","T192493-","T192494-","A192495-","G192496-","T192497-","T192498-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","G192517-","C193168T","G194067A","G194551A","A194656G","G194969-","T194970-","C194971-","T195901C","C196461T","G196580T","A196608-","A196609-","A196610-","A196611-","A196612-","A196613-","A196614-","C196735T","A197082G"],"OPG002":["V172-"],"OPG002_dup":["V172-"],"OPG003":["A189V","D489N"],"OPG005":["S3F"],"OPG021":["S219L"],"OPG023":["M109I","S258L","C304R","A426T","L602I"],"OPG027":["I47V","V126I"],"OPG029":["D153-","D154-"],"OPG031":["T80M","C241Y","G258-"],"OPG037":["C144Y"],"OPG039":["C279Y"],"OPG044":["V63A","T109A"],"OPG065":["A17T","H61N"],"OPG068":["P251S"],"OPG070":["H205Y"],"OPG072":["V10I"],"OPG076":["S20N"],"OPG080":["L521P","P582H"],"OPG085":["S79T"],"OPG089":["D303E"],"OPG091":["V62I","S73N"],"OPG092":["I244N"],"OPG108":["T111I"],"OPG109":["R364S","A630T"],"OPG113":["V537I"],"OPG117":["D454N"],"OPG120":["A19T"],"OPG123":["I172T","A313T","C436Y"],"OPG125":["E111D"],"OPG130":["A63V","L270I"],"OPG133":["F594S"],"OPG134":["E226D"],"OPG136":["A229T","D267N","F283Y"],"OPG144":["T184I"],"OPG145":["I249V"],"OPG151":["D6V","N282D"],"OPG154":["R74H"],"OPG156":["I261M"],"OPG157":["Q61-"],"OPG160":["P2S"],"OPG163":["V46A"],"OPG164":["V228-"],"OPG165":["D106N"],"OPG172":["A125V"],"OPG180":["L555-"],"OPG181":["L85M","S127Y"],"OPG188":["V265I","S419R"],"OPG189":["K185R","R506H"],"OPG191":["P50Q"],"OPG192":["G100E"],"OPG197":["M1I"],"OPG200":["E134G"],"OPG205":["R733Q"],"OPG208":["A34V","T300A"],"OPG209":["I11V","L21F"],"OPG210":["A98D","V173I","N334I","V515A","L734-"]},"labels":{"aa":"OPG002: V172-; OPG002_dup: V172-; OPG003: A189V, D489N; OPG005: S3F; OPG021: S219L; OPG023: M109I, S258L, C304R, A426T, L602I; OPG027: I47V, V126I; OPG029: D153-, D154-; OPG031: T80M, C241Y, G258-; OPG037: C144Y; OPG039: C279Y; OPG044: V63A, T109A; OPG065: A17T, H61N; OPG068: P251S; OPG070: H205Y; OPG072: V10I; OPG076: S20N; OPG080: L521P, P582H; OPG085: S79T; OPG089: D303E; OPG091: V62I, S73N; OPG092: I244N; OPG108: T111I; OPG109: R364S, A630T; OPG113: V537I; OPG117: D454N; OPG120: A19T; OPG123: I172T, A313T, C436Y; OPG125: E111D; OPG130: A63V, L270I; OPG133: F594S; OPG134: E226D; OPG136: A229T, D267N, F283Y; OPG144: T184I; OPG145: I249V; OPG151: D6V, N282D; OPG154: R74H; OPG156: I261M; OPG157: Q61-; OPG160: P2S; OPG163: V46A; OPG164: V228-; OPG165: D106N; OPG172: A125V; OPG180: L555-; OPG181: L85M, S127Y; OPG188: V265I, S419R; OPG189: K185R, R506H; OPG191: P50Q; OPG192: G100E; OPG197: M1I; OPG200: E134G; OPG205: R733Q; OPG208: A34V, T300A; OPG209: I11V, L21F; OPG210: A98D, V173I, N334I, V515A, L734-","clade":"clade I"}},"children":[{"name":"JX878417","node_attrs":{"div":301,"accession":"JX878417","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0104"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-12-14"},"strain_display":{"value":"Democratic Republic of the Congo/JX878417/2006-12-14"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T622-","C6615-","C13298T","A13302-","C13303-","C13304-","G13307-","A13308-","A13312T","A13313T","G13314T","C13316T","T13317A","G16147A","G23664T","T29805C","G31718A","C39731T","G47297T","C47929T","A49211G","C55169-","G59736A","A59910G","T70366C","T70958G","A71178-","C73040T","G87098T","C91509T","G91737A","C110159A","G117146A","G122405A","A142313G","C143414T","G143417C","T143419A","C143420-","A143421-","T143422-","G143423-","A143424-","A143425-","C143426-","C146214T","C148324A","T151060C","C159159T","C168295T","C169722-","G169724-","C169758T","A169777-","G169778-","A169779-","A169780-","G169781-","A169782-","T169783-","A169784-","T169785-","C169786-","A169787-","T169788-","G169789-","A169790-","A169791-","G169793-","A169794-","A169795-","A169796-","A172087T","C175361T","C178926-","A178927-","C179289T","T180737A","G181232A","G189594A","G191870A","A192420-","T197076G"],"OPG015_dup":["A273T"],"OPG039":["P152Q"],"OPG047":["I464V"],"OPG074":["V653-"],"OPG089":["S365A"],"OPG109":["R784S"],"OPG112":["A88V"],"OPG113":["A3T"],"OPG143":["A304V"],"OPG163":["N38D"],"OPG164":["Q213*","D214Q","H215-","E216-","H217-"],"OPG170":["G189R"],"OPG197":["T18-","D19-","T30I","E37-","D38-","I39-","M40-","N41-","E42-","I43-"],"OPG204":["T277M"],"OPG209":["S74T"]},"labels":{"aa":"OPG015_dup: A273T; OPG039: P152Q; OPG047: I464V; OPG074: V653-; OPG089: S365A; OPG109: R784S; OPG112: A88V; OPG113: A3T; OPG143: A304V; OPG163: N38D; OPG164: Q213*, D214Q, H215-, E216-, H217-; OPG170: G189R; OPG197: T18-, D19-, T30I, E37-, D38-, I39-, M40-, N41-, E42-, I43-; OPG204: T277M; OPG209: S74T"}}},{"name":"NODE_0000003","node_attrs":{"div":266,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["A204C","G994A","G16141T","C72111T","-169792C","A179227-","G186944T","G188824A","C196216T","T197006G"],"OPG027":["F79L"],"OPG210":["E1863D"]},"labels":{"aa":"OPG027: F79L; OPG210: E1863D"}},"children":[{"name":"NODE_0000004","node_attrs":{"div":272,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G1861A","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A6226-","T6227-","T6228-","C6229-","T6230-","T6281-","T6937-","G94890A","G105321T","C118612T","C121306T","A136543-","T136544-","C136545-","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","A144618G","-148336T","-173295T","-173296A","-173297T","-173298A","-173299T","-173300A","-173301T","-173302A","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T187042-","C195349T"],"OPG136":["A326T"],"OPG153":["I370D"]},"labels":{"aa":"OPG136: A326T; OPG153: I370D"}},"children":[{"name":"KJ642618","node_attrs":{"div":304,"accession":"KJ642618","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"Cameroon"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"KJ642618"},"date":{"value":"1990-XX-XX"},"strain_display":{"value":"Cameroon/KJ642618/1990-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G2075A","A4350-","G4351-","A4352-","T4353-","G4354-","G4355-","A4356-","T4357-","T4358-","A4359-","A4360-","A4361-","T4362-","C4363-","G4364-","T4365-","G4366-","T4367-","A4368-","T4369-","T4370-","C4371-","A4372-","T4373-","C4374-","G4375-","T4376-","A4377-","T4378-","A4379-","G4380-","C4381-","A4382-","A4383-","T4384-","G4385-","T4386-","A4387-","A4388-","T4389-","G4390-","G4391-","A4392-","G4393-","A4394-","G4395-","T4396-","T4397-","A4398-","C4399-","C4400-","A4401-","C4402-","A4403-","T4404-","T4405-","T4406-","T4407-","A4408-","G4409-","T4410-","C4411-","G4412-","T4413-","T4414-","T4415-","A4416-","T4417-","T4418-","C4419-","A4420-","G4421-","A4422-","T4423-","C4424-","G4425-","C4426-","A4427-","G4428-","T4429-","G4430-","T4431-","T4432-","T4433-","A4434-","A4435-","T4436-","A4437-","A4438-","C4439-","T4440-","A4441-","A4442-","T4443-","T4444-","T4445-","A4446-","A4447-","A4448-","C4449-","A4450-","G4451-","A4452-","T4453-","G4454-","A4455-","G4456-","A4457-","T4458-","G4459-","A4460-","T4461-","A4462-","T4463-","A4464-","T4465-","C4466-","C4467-","A4468-","C4469-","A4470-","T4471-","C4472-","A4473-","A4474-","A4475-","G4476-","A4477-","A4478-","T4479-","G4480-","C4481-","G4482-","A4483-","G4484-","A4485-","T4486-","A4487-","C4488-","A4489-","T4490-","A4491-","T4492-","G4493-","A4494-","C4495-","A4496-","G4497-","A4498-","C4499-","A4500-","T4501-","T4502-","A4503-","T4504-","T4505-","G4506-","A4507-","C4508-","A4509-","G4510-","A4511-","A4512-","A4513-","T4514-","G4515-","T4516-","G4517-","A4518-","C4519-","C4520-","T4521-","T4522-","C4523-","A4524-","T4525-","T4526-","A4527-","T4528-","C4529-","A4530-","C4531-","C4532-","G4533-","T4534-","C4535-","G4536-","T4537-","C4538-","C4539-","A4540-","T4541-","A4542-","A4543-","A4544-","T4545-","G4546-","C4547-","G4548-","T4549-","T4550-","A4551-","G4552-","G4553-","T4554-","A4555-","C4556-","G4557-","T4558-","A4559-","C4560-","C4561-","A4562-","C4563-","A4564-","T4565-","A4566-","C4567-","T4568-","A4569-","T4570-","C4571-","G4572-","T4573-","T4574-","A4575-","A4576-","C4577-","G4578-","A4579-","T4580-","G4581-","C4582-","G4583-","C4584-","A4585-","C4586-","A4587-","A4588-","T4589-","C4590-","T4591-","C4592-","G4593-","T4594-","C4595-","C4596-","A4597-","T4598-","T4599-","T4600-","C4601-","A4602-","T4603-","C4604-","C4605-","A4606-","T4607-","C4608-","T4609-","T4610-","C4611-","A4612-","T4613-","A4614-","A4615-","T4616-","G4617-","A4618-","T4619-","T4620-","T4621-","A4622-","C4623-","T4624-","T4625-","T4626-","T4627-","T4628-","C4629-","A4630-","T4631-","A4632-","A4633-","T4634-","T4635-","A4636-","G4637-","A4638-","G4639-","A4640-","A4641-","A4642-","A4643-","A4644-","G4645-","A4646-","T4647-","C4648-","A4649-","A4650-","G4651-","G4652-","T4653-","A4654-","T4655-","A4656-","A4657-","A4658-","A4659-","A4660-","T4661-","T4662-","A4663-","G4664-","A4665-","A4666-","G4667-","T4668-","G4669-","T4670-","T4671-","A4672-","G4673-","A4674-","C4675-","T4676-","A4677-","T4678-","A4679-","A4680-","A4681-","C4682-","T4683-","A4684-","A4685-","C4686-","T4687-","T4688-","A4689-","T4690-","A4691-","A4692-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","A4807-","T4808-","T4809-","A4810-","A4811-","C4812-","T4813-","C4814-","A4815-","T4816-","T4817-","T4818-","C4819-","A4820-","A4821-","G4822-","A4823-","A4824-","A4825-","G4826-","G4827-","T4828-","G4829-","G4830-","G4831-","T4832-","G4833-","G4834-","A4835-","G4836-","A4837-","G4838-","A4839-","A4840-","C4841-","T4842-","C4843-","T4844-","A4845-","T4846-","A4847-","T4848-","G4849-","A4850-","C4851-","A4852-","G4853-","C4854-","T4855-","T4856-","G4857-","T4858-","G4859-","A4860-","A4861-","A4862-","C4863-","A4864-","A4865-","T4866-","T4867-","A4868-","G4869-","A4870-","T4871-","C4872-","C4873-","C4874-","T4875-","A4876-","A4877-","T4878-","T4879-","T4880-","C4881-","T4882-","A4883-","A4884-","T4885-","G4886-","G4887-","A4888-","A4889-","G4890-","T4891-","T4892-","T4893-","T4894-","G4895-","A4896-","T4897-","A4898-","G4899-","G4900-","A4901-","G4902-","A4903-","T4904-","T4905-","G4906-","T4907-","C4908-","A4909-","T4910-","C4911-","A4912-","G4913-","T4914-","T4915-","G4916-","A4917-","T4918-","A4919-","C4920-","A4921-","T4922-","T4923-","G4924-","T4925-","T4926-","T4927-","A4928-","T4929-","T4930-","A4931-","T4932-","C4933-","T4934-","C4935-","A4936-","T4937-","C4938-","T4939-","A4940-","T4941-","T4942-","A4943-","G4944-","A4945-","G4946-","C4947-","A4948-","C4949-","G4950-","T4951-","C4952-","T4953-","G4954-","T4955-","T4956-","T4957-","A4958-","G4959-","A4960-","G4961-","C4962-","T4963-","T4964-","T4965-","A4966-","G4967-","T4968-","G4969-","A4970-","C4971-","C4972-","T4973-","G4974-","C4975-","T4976-","C4977-","G4978-","G4979-","T4980-","T4981-","A4982-","C4983-","T4984-","T4985-","C4986-","T4987-","G4988-","T4989-","G4990-","T4991-","A4992-","A4993-","A4994-","T4995-","C4996-","T4997-","T4998-","G4999-","A5000-","A5001-","T5002-","C5003-","C5004-","T5005-","T5006-","T5007-","A5008-","G5009-","T5010-","G5011-","A5012-","T5013-","A5014-","C5015-","A5016-","C5017-","T5018-","G5019-","T5020-","G5021-","T5022-","C5023-","A5024-","A5025-","A5026-","A5027-","C5028-","T5029-","G5030-","G5031-","A5032-","T5033-","G5034-","T5035-","T5036-","T5037-","A5038-","G5039-","A5040-","A5041-","T5042-","A5043-","C5044-","C5045-","T5046-","A5047-","T5048-","G5049-","T5050-","A5051-","G5052-","A5053-","A5054-","T5055-","A5056-","T5057-","G5058-","G5059-","G5060-","A5061-","A5062-","G5063-","C5064-","A5065-","T5066-","G5067-","C5068-","T5069-","T5070-","G5071-","T5072-","T5073-","T5074-","T5075-","T5076-","G5077-","T5078-","C5079-","T5080-","C5081-","T5082-","A5083-","T5084-","T5085-","A5086-","T5087-","A5088-","G5089-","A5090-","T5091-","T5092-","A5093-","A5094-","C5095-","T5096-","C5097-","A5098-","T5099-","A5100-","C5101-","A5102-","T5103-","G5104-","G5105-","T5106-","T5107-","G5108-","T5109-","A5110-","T5111-","T5112-","A5113-","T5114-","G5115-","A5116-","A5117-","T5118-","T5119-","T5120-","T5121-","C5122-","A5123-","T5124-","C5125-","T5126-","G5127-","C5128-","C5129-","T5130-","A5131-","A5132-","T5133-","G5134-","T5135-","A5136-","C5137-","T5138-","C5139-","C5140-","A5141-","A5142-","T5143-","T5144-","C5145-","T5146-","T5147-","G5148-","T5149-","T5150-","T5151-","A5152-","C5153-","A5154-","A5155-","T5156-","C5157-","A5158-","A5159-","T5160-","T5161-","A5162-","T5163-","A5164-","T5165-","A5166-","A5167-","T5168-","C5169-","A5170-","A5171-","A5172-","G5173-","A5174-","G5175-","T5176-","G5177-","A5178-","T5179-","G5180-","A5181-","T5182-","G5183-","C5184-","A5185-","T5186-","A5187-","C5188-","A5189-","C5190-","A5191-","T5192-","T5193-","A5194-","C5195-","A5196-","A5197-","A5198-","G5199-","T5200-","G5201-","A5202-","A5203-","T5204-","A5205-","A5206-","T5207-","C5208-","T5209-","A5210-","C5211-","C5212-","A5213-","T5214-","C5215-","A5216-","T5217-","A5218-","A5219-","A5220-","A5221-","T5222-","A5223-","C5224-","T5225-","T5226-","G5227-","A5228-","T5229-","A5230-","C5231-","A5232-","G5233-","A5234-","G5235-","C5236-","T5237-","T5238-","T5239-","A5240-","T5241-","C5242-","A5243-","C5244-","A5245-","T5246-","C5247-","A5248-","T5249-","G5250-","G5251-","T5252-","T5253-","T5254-","T5255-","C5256-","A5257-","A5258-","T5259-","T5260-","G5261-","T5262-","A5263-","T5264-","T5265-","A5266-","T5267-","T5268-","A5269-","A5270-","G5271-","T5272-","A5273-","T5274-","A5275-","G5276-","C5277-","T5278-","A5279-","A5280-","T5281-","T5282-","T5283-","T5284-","A5285-","T5286-","A5287-","C5288-","A5289-","G5290-","T5291-","C5292-","A5293-","A5294-","T5295-","A5296-","G5297-","A5298-","C5299-","A5300-","A5301-","T5302-","G5303-","G5304-","T5305-","T5306-","C5307-","T5308-","C5309-","T5310-","A5311-","A5312-","G5313-","C5314-","A5315-","A5316-","T5317-","A5318-","T5319-","T5320-","T5321-","C5322-","T5323-","A5324-","A5325-","T5326-","A5327-","T5328-","T5329-","T5330-","T5331-","A5332-","A5333-","G5334-","A5335-","T5336-","G5337-","T5338-","G5339-","C5340-","T5341-","T5342-","C5343-","C5344-","C5345-","T5346-","A5347-","C5348-","G5349-","G5350-","G5351-","C5352-","G5353-","A5354-","T5355-","G5356-","A5357-","C5358-","A5359-","G5360-","A5361-","T5362-","C5363-","C5364-","C5365-","C5366-","T5367-","A5368-","T5369-","C5370-","C5371-","A5372-","C5373-","G5374-","G5375-","C5376-","C5377-","A5378-","C5379-","G5380-","T5381-","C5382-","A5383-","A5384-","G5385-","A5386-","C5387-","A5388-","T5389-","G5390-","T5391-","A5392-","T5393-","A5394-","T5395-","C5396-","C5397-","A5398-","T5399-","T5400-","A5401-","C5402-","T5403-","C5404-","A5405-","T5406-","T5407-","A5408-","C5409-","T5410-","G5411-","C5412-","G5413-","T5414-","T5415-","G5416-","A5417-","C5418-","A5419-","T5420-","T5421-","T5422-","G5423-","C5424-","T5425-","C5426-","C5427-","A5428-","T5429-","T5430-","T5431-","T5432-","C5433-","T5434-","A5435-","A5436-","T5437-","A5438-","G5439-","C5440-","C5441-","A5442-","T5443-","G5444-","A5445-","T5446-","A5447-","C5448-","T5449-","A5450-","A5451-","A5452-","T5453-","C5454-","T5455-","A5456-","T5457-","A5458-","T5459-","A5460-","A5461-","C5462-","C5463-","T5464-","G5465-","C5466-","A5467-","T5468-","A5469-","G5470-","A5471-","T5472-","A5473-","G5474-","C5475-","G5476-","C5477-","G5478-","A5479-","T5480-","A5481-","A5482-","A5483-","G5484-","C5485-","A5486-","A5487-","G5488-","G5489-","T5490-","C5491-","C5492-","T5493-","T5494-","C5495-","C5496-","A5497-","C5498-","C5499-","A5500-","G5501-","C5502-","A5503-","T5504-","C5505-","T5506-","A5507-","G5508-","T5509-","T5510-","G5511-","A5512-","T5513-","T5514-","G5515-","A5516-","T5517-","A5518-","T5519-","C5520-","T5521-","T5522-","C5523-","A5524-","A5525-","T5526-","A5527-","T5528-","A5529-","T5530-","G5531-","G5532-","G5533-","A5534-","T5535-","A5536-","C5537-","A5538-","A5539-","A5540-","G5541-","C5542-","T5543-","T5544-","A5545-","T5546-","A5547-","A5548-","A5549-","T5550-","T5551-","T5552-","C5553-","T5554-","A5555-","A5556-","T5557-","A5558-","C5559-","T5560-","G5561-","T5562-","G5563-","G5564-","G5565-","T5566-","T5567-","C5568-","A5569-","T5570-","C5571-","T5572-","A5573-","C5574-","A5575-","A5576-","G5577-","G5578-","A5579-","A5580-","T5581-","C5582-","C5583-","C5584-","C5585-","T5586-","A5587-","G5588-","T5589-","A5590-","T5591-","A5592-","C5593-","T5594-","G5595-","A5596-","A5597-","T5598-","T5599-","A5600-","T5601-","T5602-","T5603-","T5604-","A5605-","T5606-","A5607-","T5608-","A5609-","G5610-","A5611-","T5612-","C5613-","T5614-","A5615-","A5616-","T5617-","T5618-","T5619-","A5620-","A5621-","C5622-","A5623-","T5624-","C5625-","A5626-","T5627-","T5628-","T5629-","T5630-","C5631-","A5632-","T5633-","C5634-","T5635-","G5636-","G5637-","G5638-","A5639-","T5640-","A5641-","C5642-","C5643-","A5644-","C5645-","A5646-","A5647-","T5648-","T5649-","C5650-","A5651-","A5652-","A5653-","A5654-","T5655-","A5656-","A5657-","A5658-","C5659-","T5660-","C5661-","A5662-","A5663-","C5664-","A5665-","A5666-","C5667-","A5668-","C5669-","T5670-","A5671-","C5672-","T5673-","T5674-","T5675-","C5676-","C5677-","T5678-","T5679-","T5680-","T5681-","T5682-","A5683-","C5684-","A5685-","T5686-","A5687-","T5688-","T5689-","C5690-","C5691-","C5692-","C5693-","T5694-","A5695-","A5696-","A5697-","A5698-","T5699-","A5700-","G5701-","G5702-","C5703-","A5704-","T5705-","T5706-","C5707-","A5708-","A5709-","G5710-","C5711-","A5712-","T5713-","T5714-","C5715-","T5716-","A5717-","T5718-","T5719-","T5720-","T5721-","A5722-","T5723-","A5724-","T5725-","A5726-","T5727-","T5728-","A5729-","C5730-","A5731-","G5732-","C5733-","C5734-","C5735-","C5736-","A5737-","T5738-","G5739-","A5740-","T5741-","C5742-","T5743-","A5744-","C5745-","C5746-","A5747-","T5748-","A5749-","A5750-","A5751-","A5752-","T5753-","C5754-","A5755-","A5756-","C5757-","A5758-","A5759-","T5760-","G5761-","T5762-","C5763-","T5764-","A5765-","T5766-","T5767-","T5768-","C5769-","T5770-","A5771-","C5772-","A5773-","T5774-","A5775-","T5776-","G5777-","C5778-","A5779-","T5780-","T5781-","A5782-","G5783-","A5784-","T5785-","A5786-","G5787-","A5788-","T5789-","A5790-","G5791-","T5792-","A5793-","A5794-","A5795-","G5796-","T5797-","A5798-","A5799-","G5800-","A5801-","G5802-","A5803-","T5804-","C5805-","T5806-","T5807-","G5808-","T5809-","A5810-","C5811-","A5812-","G5813-","A5814-","A5815-","T5816-","T5817-","A5818-","C5819-","A5820-","A5821-","T5822-","T5823-","C5824-","T5825-","T5826-","A5827-","A5828-","T5829-","A5830-","A5831-","T5832-","T5833-","A5834-","T5835-","A5836-","G5837-","A5838-","G5839-","A5840-","A5841-","A5842-","A5843-","T5844-","A5845-","T5846-","C5847-","T5848-","T5849-","C5850-","C5851-","A5852-","T5853-","A5854-","T5855-","A5856-","A5857-","T5858-","T5859-","C5860-","T5861-","T5862-","T5863-","G5864-","A5865-","C5866-","A5867-","C5868-","T5869-","A5870-","A5871-","T5872-","G5873-","C5874-","A5875-","G5876-","A5877-","T5878-","A5879-","T5880-","A5881-","A5882-","T5883-","A5884-","T5885-","C5886-","T5887-","T5888-","T5889-","A5890-","T5891-","A5892-","T5893-","G5894-","T5895-","A5896-","A5897-","T5898-","A5899-","T5900-","A5901-","T5902-","G5903-","C5904-","A5905-","A5906-","A5907-","C5908-","A5909-","G5910-","T5911-","C5912-","T5913-","A5914-","T5915-","C5916-","T5917-","A5918-","C5919-","T5920-","A5921-","T5922-","A5923-","T5924-","A5925-","C5926-","T5927-","G5928-","A5929-","T5930-","C5931-","A5932-","A5933-","T5934-","A5935-","T5936-","T5937-","A5938-","T5939-","C5940-","T5941-","C5942-","T5943-","A5944-","T5945-","G5946-","A5947-","A5948-","T5949-","C5950-","C5951-","T5952-","A5953-","A5954-","A5955-","A5956-","T5957-","A5958-","A5959-","T5960-","C5961-","A5962-","T5963-","A5964-","C5965-","A5966-","G5967-","A5968-","A5969-","C5970-","A5971-","T5972-","C5973-","T5974-","A5975-","C5976-","A5977-","G5978-","G5979-","A5980-","T5981-","C5982-","A5983-","C5984-","A5985-","A5986-","A5987-","T5988-","T5989-","G5990-","G5991-","T5992-","T5993-","C5994-","A5995-","A5996-","G5997-","G5998-","A5999-","G6000-","A6001-","A6002-","A6003-","T6004-","C6005-","T6006-","A6007-","T6008-","C6009-","A6010-","A6011-","A6012-","T6013-","A6014-","T6015-","T6016-","T6017-","T6018-","C6019-","C6020-","T6021-","G6022-","T6023-","C6024-","A6025-","A6026-","C6027-","A6028-","A6029-","C6030-","T6031-","G6032-","G6033-","T6034-","T6035-","C6036-","T6037-","A6038-","G6039-","A6040-","A6041-","C6042-","A6043-","T6044-","A6045-","A6046-","C6047-","A6048-","G6049-","T6050-","C6051-","A6052-","A6053-","C6054-","A6055-","C6056-","C6057-","T6058-","A6059-","A6060-","T6061-","C6062-","C6063-","A6064-","T6065-","G6066-","T6067-","T6068-","T6069-","T6070-","T6071-","T6072-","A6073-","T6074-","A6075-","G6076-","T6077-","C6078-","A6079-","T6080-","C6081-","T6082-","A6083-","C6084-","C6085-","A6086-","A6087-","A6088-","G6089-","A6090-","T6091-","A6092-","A6093-","T6094-","G6095-","A6096-","C6097-","C6098-","A6099-","A6100-","A6101-","G6102-","A6103-","T6104-","C6105-","G6106-","A6107-","G6108-","G6109-","T6110-","C6111-","G6112-","T6113-","C6114-","G6115-","T6116-","G6117-","A6118-","A6119-","A6120-","C6121-","T6122-","G6123-","C6124-","T6125-","C6126-","A6127-","T6128-","C6129-","G6130-","A6131-","C6132-","A6133-","G6134-","C6135-","C6136-","A6137-","T6138-","G6139-","A6140-","A6141-","A6142-","T6143-","C6144-","T6145-","G6146-","C6147-","C6148-","G6149-","A6150-","C6151-","T6152-","C6153-","C6154-","A6155-","T6156-","G6157-","G6158-","C6159-","G6160-","C6161-","G6162-","A6163-","A6164-","T6165-","C6166-","G6167-","C6168-","A6169-","C6170-","T6171-","G6172-","T6173-","C6174-","T6175-","T6176-","A6177-","T6178-","T6179-","C6180-","G6181-","C6182-","C6183-","A6184-","T6185-","T6186-","G6187-","A6188-","T6189-","T6190-","T6191-","T6192-","C6193-","A6194-","T6195-","T6196-","T6197-","T6198-","T6199-","T6200-","A6201-","T6202-","A6203-","A6204-","T6205-","T6206-","A6207-","T6208-","G6209-","T6210-","A6211-","C6212-","A6213-","T6214-","G6215-","T6216-","T6217-","T6218-","T6219-","C6220-","C6221-","T6222-","T6223-","C6224-","T6225-","C6231-","A6232-","A6233-","G6234-","A6235-","G6236-","T6237-","C6238-","T6239-","A6240-","C6241-","A6242-","A6243-","A6244-","A6245-","A6246-","T6247-","A6248-","T6249-","A6250-","T6251-","T6252-","T6253-","T6254-","T6255-","T6256-","C6257-","G6258-","A6259-","T6260-","A6261-","T6262-","C6263-","T6264-","A6265-","A6266-","G6267-","T6268-","A6269-","C6270-","T6271-","A6272-","A6273-","G6274-","T6275-","T6276-","T6277-","T6278-","T6279-","T6280-","A6282-","C6283-","T6284-","G6285-","T6286-","T6287-","T6288-","T6289-","T6290-","G6291-","T6292-","T6293-","A6294-","C6295-","T6296-","G6297-","T6298-","C6299-","T6300-","T6301-","C6302-","C6303-","A6304-","T6305-","T6306-","C6307-","T6308-","T6309-","C6310-","T6311-","A6312-","A6313-","C6314-","T6315-","A6316-","A6317-","A6318-","G6319-","A6320-","T6321-","C6322-","T6323-","G6324-","A6325-","G6326-","A6327-","T6328-","A6329-","A6330-","A6331-","T6332-","T6333-","A6334-","T6335-","A6336-","C6337-","A6338-","A6339-","T6340-","C6341-","T6342-","T6343-","C6344-","G6345-","C6346-","T6347-","A6348-","T6349-","C6350-","G6351-","A6352-","A6353-","C6354-","C6355-","A6356-","T6357-","T6358-","T6359-","T6360-","T6361-","G6362-","T6363-","A6364-","G6365-","T6366-","C6367-","T6368-","A6369-","A6370-","A6371-","G6372-","C6373-","C6374-","T6375-","G6376-","A6377-","A6378-","G6379-","T6380-","A6381-","A6382-","T6383-","T6384-","A6385-","A6386-","C6387-","C6388-","A6389-","A6390-","C6391-","T6392-","G6393-","T6394-","T6395-","T6396-","T6397-","T6398-","A6399-","T6400-","T6401-","A6402-","G6403-","T6404-","G6405-","G6406-","C6407-","T6408-","T6409-","T6410-","T6411-","T6412-","T6413-","C6414-","G6415-","A6416-","T6417-","C6418-","T6419-","A6420-","T6421-","C6422-","C6423-","T6424-","C6425-","G6426-","T6427-","C6428-","C6429-","T6430-","C6431-","A6434-","T6435-","C6436-","A6437-","T6438-","C6439-","C6440-","T6441-","T6442-","A6443-","T6444-","A6445-","T6446-","T6447-","A6448-","T6449-","T6450-","A6451-","T6452-","C6453-","A6454-","T6455-","T6456-","A6457-","T6458-","T6459-","A6460-","T6461-","C6462-","A6463-","T6464-","A6465-","G6466-","T6467-","C6468-","T6469-","A6470-","T6471-","T6472-","A6473-","A6474-","A6475-","C6476-","A6477-","C6478-","A6479-","A6480-","A6481-","T6482-","C6483-","A6484-","T6485-","C6486-","T6487-","A6488-","C6489-","G6490-","T6491-","T6492-","T6493-","A6494-","T6495-","A6496-","A6497-","C6498-","A6499-","A6500-","C6501-","A6502-","T6503-","T6504-","C6505-","T6506-","C6507-","A6508-","T6509-","T6510-","A6511-","T6512-","T6513-","A6514-","A6515-","T6516-","T6517-","A6518-","G6519-","T6520-","T6521-","C6522-","T6523-","G6524-","T6525-","A6526-","G6527-","A6528-","A6529-","T6530-","A6531-","T6532-","C6533-","T6534-","T6535-","T6536-","A6537-","A6538-","T6539-","A6540-","A6541-","T6542-","T6543-","T6544-","G6545-","G6546-","C6547-","T6548-","A6549-","T6550-","A6551-","C6552-","A6553-","T6554-","C6555-","T6556-","G6557-","T6558-","T6559-","C6560-","A6561-","A6562-","T6563-","A6564-","C6565-","T6566-","A6567-","T6568-","C6569-","T6570-","A6571-","T6572-","T6573-","G6574-","A6575-","T6576-","G6577-","A6578-","T6579-","T6580-","T6581-","C6582-","T6583-","T6584-","T6585-","T6586-","T6587-","T6588-","A6589-","A6590-","G6591-","A6592-","C6593-","T6594-","T6595-","A6596-","A6597-","A6598-","C6599-","T6600-","A6601-","G6602-","T6603-","T6604-","A6605-","T6606-","G6607-","G6608-","T6609-","A6610-","A6611-","T6612-","G6613-","A6614-","C6615-","G6616-","A6617-","T6618-","G6619-","A6620-","A6621-","A6622-","T6623-","C6624-","G6625-","A6626-","G6627-","T6628-","A6629-","G6630-","T6631-","A6632-","A6633-","C6634-","T6635-","T6636-","C6637-","T6638-","A6639-","A6640-","T6641-","A6642-","A6643-","A6644-","G6645-","A6646-","C6647-","T6648-","T6649-","G6650-","A6651-","T6652-","A6653-","T6654-","C6655-","A6656-","T6657-","T6658-","A6659-","T6660-","C6661-","A6662-","T6663-","A6664-","T6665-","G6666-","T6667-","T6668-","T6669-","G6670-","A6671-","T6672-","C6673-","G6674-","T6675-","C6676-","A6677-","T6678-","A6679-","G6680-","T6681-","T6682-","A6683-","A6684-","T6685-","A6686-","G6687-","T6688-","G6689-","T6690-","G6691-","G6692-","C6693-","T6694-","A6695-","A6696-","A6697-","T6698-","G6699-","G6700-","T6701-","A6702-","C6703-","T6704-","G6705-","T6706-","T6707-","A6708-","A6709-","T6710-","A6711-","A6712-","G6713-","T6714-","T6715-","T6716-","A6717-","T6718-","A6719-","G6720-","A6721-","C6722-","A6723-","A6724-","T6725-","A6726-","T6727-","C6728-","A6729-","T6730-","A6731-","G6732-","T6733-","A6734-","T6735-","T6736-","T6737-","T6738-","C6739-","T6740-","T6741-","T6742-","C6743-","C6744-","A6745-","G6746-","A6747-","A6748-","T6749-","T6750-","A6751-","G6752-","A6753-","T6754-","T6755-","A6756-","T6757-","T6758-","T6759-","T6760-","T6761-","T6762-","T6763-","A6764-","A6765-","A6766-","T6767-","A6768-","C6769-","T6770-","G6771-","A6772-","T6773-","C6774-","C6775-","T6776-","C6777-","A6778-","C6779-","A6780-","A6781-","T6782-","T6783-","C6784-","C6785-","G6786-","T6787-","G6788-","A6789-","T6790-","G6791-","T6792-","A6793-","G6794-","C6795-","A6796-","G6797-","T6798-","A6799-","G6800-","T6801-","T6802-","G6803-","G6804-","T6805-","G6806-","C6807-","A6808-","T6809-","G6810-","G6811-","T6812-","C6813-","T6814-","A6815-","T6816-","A6817-","T6818-","C6819-","G6820-","T6821-","T6822-","A6823-","A6824-","A6825-","A6826-","T6827-","G6828-","T6829-","A6830-","T6831-","C6832-","A6833-","T6834-","A6835-","T6836-","A6837-","T6838-","A6839-","A6840-","T6841-","A6842-","G6843-","T6844-","T6845-","T6846-","T6847-","C6848-","T6849-","G6850-","A6851-","C6852-","G6853-","T6854-","G6855-","G6856-","A6857-","G6858-","T6859-","A6860-","C6861-","A6862-","G6863-","A6864-","A6865-","T6866-","T6867-","T6868-","T6869-","C6870-","G6871-","A6872-","T6873-","T6874-","A6875-","A6876-","T6877-","G6878-","A6879-","G6880-","T6881-","T6882-","C6883-","A6884-","T6885-","G6886-","G6887-","T6888-","A6889-","A6890-","G6891-","G6892-","A6893-","A6894-","G6895-","G6896-","G6897-","C6898-","A6899-","A6900-","A6901-","T6902-","G6903-","T6904-","C6905-","T6906-","G6907-","T6908-","A6909-","T6910-","A6911-","T6912-","A6913-","A6914-","T6915-","A6916-","T6917-","A6918-","C6919-","A6920-","T6921-","A6922-","A6923-","G6924-","T6925-","T6926-","A6927-","A6928-","T6929-","A6930-","G6931-","T6932-","T6933-","T6934-","T6935-","T6936-","A6938-","T6939-","C6940-","A6941-","T6942-","A6943-","T6944-","T6945-","T6946-","T6947-","C6948-","T6949-","A6950-","A6951-","T6952-","A6953-","C6954-","C6955-","A6956-","T6957-","A6958-","A6959-","T6960-","A6961-","A6962-","A6963-","A6964-","A6965-","T6966-","T6967-","A6968-","T6969-","C6970-","A6971-","T6972-","T6973-","A6974-","T6975-","T6976-","G6977-","C6978-","G6979-","T6980-","T6981-","T6982-","G6983-","G6984-","T6985-","A6986-","G6987-","A8366C","G8599A","G10923A","T12181A","T15127-","C17933T","T18703C","C21073A","C29763T","G33053A","A35238G","A38984G","G46402T","G47539A","C47904-","C47905-","G64207A","T66182C","G69898A","A88356G","G102985T","C109017T","C115292T","G133070A","A136512C","T136555-","A136556-","T136557-","G136558-","A136559-","T136560-","A136561-","T136562-","C136563-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","C142360T","C145930-","G148718A","C152844T","C158803A","C159989T","C160938T","C166345A","G167529T","G169595A","-169721A","-169723A","-169725A","-169726T","A172087T","A173273-","A173274-","T173275-","A173276-","T173277-","A173278-","T173279-","A173280-","T173281-","A173282-","T173283-","A173284-","T173285-","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","C174599T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C192693T","C195135T"],"OPG002":["A226V"],"OPG002_dup":["A226V"],"OPG023":["Q660*"],"OPG031":["C299Y"],"OPG047":["D478N"],"OPG065":["R28S"],"OPG153":["D370-","I371-","D372-","D373-","D374-","D375-","D376-","D377-","D378-","Y386D"],"OPG187":["A106V"],"OPG191":["S62*"],"OPG193":["D66Y"],"OPG204":["A23V"]},"labels":{"aa":"OPG002: A226V; OPG002_dup: A226V; OPG023: Q660*; OPG031: C299Y; OPG047: D478N; OPG065: R28S; OPG153: D370-, I371-, D372-, D373-, D374-, D375-, D376-, D377-, D378-, Y386D; OPG187: A106V; OPG191: S62*; OPG193: D66Y; OPG204: A23V"}}},{"name":"NODE_0000005","node_attrs":{"div":297,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G8394T","C10147T","G11051A","G15606A","G18280A","G21146T","T32747C","G36045T","C39311G","A45542G","G84665A","A92711G","G114697T","G135808A","A136537-","T136538-","C136539-","A136540-","T136541-","C136542-","-140134A","-140135A","-140136C","-140137A","-140138A","-140139T","-140140T","-140141A","-140142T","C145551G","C148484T","T148958C","C156205T","A156206C","-156210A","C169722-","G169724-","C170542T","A172885-","-173286A","-173287T","-173288A","-173289T","-173290A","-173291T","-173292A","-173293T","-173294A","G173318-","G173595A","G176943A","C188468T","A188511G","C190447T","A190935-","T190984-","A190985-","G190986-","A190987-","A190988-","A192419-","A192420-","G192421-","T192422-","C192423-","A192424-","T192425-","A192426-","A192427-","G192428-","T192429-","T192430-","A192431-","G192432-","T192433-","T192434-"],"OPG016":["A13V","T176-"],"OPG023":["A617V"],"OPG037":["H430N"],"OPG055":["L347I"],"OPG133":["P334T"],"OPG153":["D372I","D381-","D382-","D383-","D384-","D385-"],"OPG159":["-124N","-125Y","-126N"],"OPG197":["T18-","D19-"],"OPG198":["H169Y"],"OPG205":["A430T"]},"labels":{"aa":"OPG016: A13V, T176-; OPG023: A617V; OPG037: H430N; OPG055: L347I; OPG133: P334T; OPG153: D372I, D381-, D382-, D383-, D384-, D385-; OPG159: -124N, -125Y, -126N; OPG197: T18-, D19-; OPG198: H169Y; OPG205: A430T"}},"children":[{"name":"KJ642619","node_attrs":{"div":299,"accession":"KJ642619","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"Gabon"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"KJ642619"},"date":{"value":"1988-XX-XX"},"strain_display":{"value":"Gabon/KJ642619/1988-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A24147T","T24148A"]}}},{"name":"OP498046","node_attrs":{"div":301,"accession":"OP498046","author":{"author":"Emmerich,P.,Bialonski,A.,Tomazatos,A.,Cadar,D.","value":"Emmerich,P.,Bialonski,A.,Tomazatos,A.,Cadar,D."},"country":{"value":"Gabon"},"institution":{"value":"Bernhard Nocht Institute for Tropical Medicine, Arbovirology and Entomology"},"strain":{"value":"BNITM-Gabon1988"},"host":{"value":"Homo sapiens"},"date":{"value":"1988-XX-XX"},"strain_display":{"value":"Gabon/OP498046/1988-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G11865C","T24612C","C151380T","G171690A"],"OPG023":["L346V"],"OPG199":["D235N"]},"labels":{"aa":"OPG023: L346V; OPG199: D235N"}}}]}]},{"name":"NODE_0000006","node_attrs":{"div":278,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G40182A","C54569A","G56397T","C57678T","C87267T","C109535A","G122405A","A134326G","G145959A","G146433A","A165096G","A179236G","G187305A"],"OPG057":["A5V"],"OPG072":["L34I"],"OPG143":["A304V"],"OPG170":["H116Y"]},"labels":{"aa":"OPG057: A5V; OPG072: L34I; OPG143: A304V; OPG170: H116Y"}},"children":[{"name":"KJ642612","node_attrs":{"div":300,"accession":"KJ642612","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"KJ642612"},"date":{"value":"1986-XX-XX"},"strain_display":{"value":"Democratic Republic of the Congo/KJ642612/1986-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G18301A","C29763T","G31718A","T33822A","G35972T","G39173A","G53569A","G53953A","T77412A","T90138C","A91005G","G96915A","G107670A","C117896T","C128183A","-148336T","G150582T","T151256A","T151769C","-169721A","-169723A","-169725A","-169726T","A172087T","C176495T","A179137G","C179145T","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","A181253-","C181619T","T187676C","T187975-","A187976-","A190302G","G197006T"],"OPG047":["D478N"],"OPG054":["P9T"]},"labels":{"aa":"OPG047: D478N; OPG054: P9T"}}},{"name":"NODE_0000007","node_attrs":{"div":291,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T622-","C5340T","C8344A","C15209A","C21369A","T52086C","A71178-","C76021T","T82313C","G98856A","G122351A","G129583T","T150936C","G154730A","C169722-","G169724-","C169758T","A169777-","G169778-","A169779-","A169780-","G169781-","A169782-","T169783-","A169784-","T169785-","C169786-","A169787-","T169788-","G169789-","A169790-","A169791-","C169792-","G169793-","A169794-","A169795-","A169796-","C171561T","-179227G","G191870A","A196593-"],"OPG015":["A273T"],"OPG015_dup":["A273T"],"OPG025":["S20I"],"OPG037":["M355I"],"OPG071":["N785D"],"OPG143":["A322V"],"OPG181":["A107T"],"OPG197":["T18-","D19-","T30I","E37-","D38-","I39-","M40-","N41-","E42-","I43-"],"OPG199":["P192S"]},"labels":{"aa":"OPG015: A273T; OPG015_dup: A273T; OPG025: S20I; OPG037: M355I; OPG071: N785D; OPG143: A322V; OPG181: A107T; OPG197: T18-, D19-, T30I, E37-, D38-, I39-, M40-, N41-, E42-, I43-; OPG199: P192S"}},"children":[{"name":"NODE_0000008","node_attrs":{"div":292,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C19745T"]}},"children":[{"name":"NC_003310","node_attrs":{"div":388,"accession":"NC_003310","author":{"author":"Senkevich,T.G.,Yutin,N.,Wolf,Y.I.,Koonin,E.V.,Moss,B.,Zmasek,C.M.,Knipe,D.M.,Pellett,P.E.,Scheuermann,R.H.,Shchelkunov,S.N.,Totmenin,A.V.,Babkin,I.V.,Safronov,P.F.,Ryazankina,O.I.,Petrov,N.A.,Gutorov,V.V.,Uvarova,E.A.,Mikheev,M.V.,Sisler,J.R.,Esposito,J.J.,Jahrling,P.B.,Sandakhchiev,L.S.","value":"Senkevich,T.G.,Yutin,N.,Wolf,Y.I.,Koonin,E.V.,Moss,B.,Zmasek,C.M.,Knipe,D.M.,Pellett,P.E.,Scheuermann,R.H.,Shchelkunov,S.N.,Totmenin,A.V.,Babkin,I.V.,Safronov,P.F.,Ryazankina,O.I.,Petrov,N.A.,Gutorov,V.V.,Uvarova,E.A.,Mikheev,M.V.,Sisler,J.R.,Esposito,J.J.,Jahrling,P.B.,Sandakhchiev,L.S."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Department of Molecular Biology of Genomes, SRC VB Vector, Russia"},"strain":{"value":"NC_003310"},"host":{"value":"Homo sapiens"},"date":{"value":"1996-XX-XX"},"strain_display":{"value":"Democratic Republic of the Congo/NC_003310/1996-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T2688A","G9441A","A24393T","C24945T","C26416T","A27114-","T27328C","C29029T","T29031C","T29753C","T29758C","T30743A","T30815A","T30855A","G32024A","A32322G","T32329C","T33159C","G34800A","T34944A","G35230A","G35775A","T37957A","C38427T","T38658A","A39070T","T39072A","-39076T","T39447C","A40487T","A50294G","G59966C","T60903A","C60947T","T61241C","A61926C","T62169A","G62941T","T65141C","T65870C","A67348G","C67353T","A70503T","T71422C","A73777T","T74112C","A75351T","C76284T","T78525C","A81969-","C82417T","T82548C","T82641G","C83956T","G88318A","T108302C","A115794G","T122451C","T122935C","T122986C","T124980C","T125566C","T125834C","T126192C","T126231C","T126963C","T130725C","A130822C","G134912A","T136637C","T138948C","T139755C","T140893C","T141277A","A141901G","G142068A","A143024T","G143126A","A143187T","A143703G","C143806T","T143895C","C158963T","G161650A","T165054-","C165055-","G166518A","C167064T","T168214-","A168962-","A169025-","T169165-","A169581-","T169894C","A170077G","C182952T","T182953C","C183492A","C183522A","C184979T","A185373G","G185472A","T186503C","T186531G","C186532T","A187305G","A194522T"],"OPG002":["I22L"],"OPG002_dup":["I22L"],"OPG042":["G228R"],"OPG043":["N210D"],"OPG045":["R78G"],"OPG047":["N114Y","E127V","H151L","E481G"],"OPG049":["T275A","M277T"],"OPG054":["A256V"],"OPG056":["N126I","C203Y","T360S"],"OPG057":["N250S"],"OPG059":["Y49*"],"OPG080":["S260G","G358R","P685A"],"OPG082":["T171K"],"OPG085":["L395P"],"OPG089":["K213I"],"OPG091":["F18S"],"OPG097":["D198N"],"OPG101":["F14L"],"OPG105":["K282-","A431V","C475R","Y506D","S944F"],"OPG109":["A377V"],"OPG127":["K175R"],"OPG143":["T289A"],"OPG145":["L345P"],"OPG146":["D25G"],"OPG147":["S52G"],"OPG151":["M601T","E633D"],"OPG153":["N344S"],"OPG156":["I154M"],"OPG160":["K61R"],"OPG161":["L59Q"],"OPG162":["R84G"],"OPG164":["N83Y","E117K","Q137L"],"OPG165":["D63G","I127T"],"OPG185":["A16V"],"OPG188":["G19R"],"OPG191":["A120T"],"OPG192":["H112Y"],"OPG198":["K14E"],"OPG210":["L533S","P713T","P723T","T1340A","A1373T","S1726V"]},"labels":{"aa":"OPG002: I22L; OPG002_dup: I22L; OPG042: G228R; OPG043: N210D; OPG045: R78G; OPG047: N114Y, E127V, H151L, E481G; OPG049: T275A, M277T; OPG054: A256V; OPG056: N126I, C203Y, T360S; OPG057: N250S; OPG059: Y49*; OPG080: S260G, G358R, P685A; OPG082: T171K; OPG085: L395P; OPG089: K213I; OPG091: F18S; OPG097: D198N; OPG101: F14L; OPG105: K282-, A431V, C475R, Y506D, S944F; OPG109: A377V; OPG127: K175R; OPG143: T289A; OPG145: L345P; OPG146: D25G; OPG147: S52G; OPG151: M601T, E633D; OPG153: N344S; OPG156: I154M; OPG160: K61R; OPG161: L59Q; OPG162: R84G; OPG164: N83Y, E117K, Q137L; OPG165: D63G, I127T; OPG185: A16V; OPG188: G19R; OPG191: A120T; OPG192: H112Y; OPG198: K14E; OPG210: L533S, P713T, P723T, T1340A, A1373T, S1726V"}}},{"name":"JX878418","node_attrs":{"div":303,"accession":"JX878418","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0120"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-01-02"},"strain_display":{"value":"Democratic Republic of the Congo/JX878418/2007-01-02"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G1934A","A50236G","G60803T","G74360A","G95577A","G116628T","C120371T","C151006A","C174070T","G187369A","A187951C","C195276T"],"OPG002":["T273M"],"OPG002_dup":["T273M"],"OPG069":["Q84R"],"OPG080":["L406I"],"OPG094":["R194H"],"OPG116":["D73N"],"OPG134":["*293Y"],"OPG135":["S95Y"],"OPG137":["A257V"]},"labels":{"aa":"OPG002: T273M; OPG002_dup: T273M; OPG069: Q84R; OPG080: L406I; OPG094: R194H; OPG116: D73N; OPG134: *293Y; OPG135: S95Y; OPG137: A257V"}}}]},{"name":"NODE_0000009","node_attrs":{"div":292,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G32003A"]}},"children":[{"name":"JX878426","node_attrs":{"div":301,"accession":"JX878426","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0450"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-05-27"},"strain_display":{"value":"Democratic Republic of the Congo/JX878426/2007-05-27"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G19563A","G38096T","G54227A","-71178A","A72767T","G111583A","T121790C","A160337-","C166976T","C185501T","G189591A"],"OPG005":["M131I"],"OPG034":["A148V"],"OPG071":["T71I"],"OPG092":["S61T"],"OPG130":["T107I"],"OPG141":["I45M"]},"labels":{"aa":"OPG005: M131I; OPG034: A148V; OPG071: T71I; OPG092: S61T; OPG130: T107I; OPG141: I45M"}}},{"name":"JX878408","node_attrs":{"div":292,"accession":"JX878408","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 06-0970"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-10-31"},"strain_display":{"value":"Democratic Republic of the Congo/JX878408/2006-10-31"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000010","node_attrs":{"div":297,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C7495-","A7496-","A7497-","T7498-","T7499-","A7500-","G24032A","G94972A","G137606T","C149206G","G160867A","C170296A"],"OPG115":["V105I"],"OPG153":["A21E"],"OPG174":["E64Q"],"OPG198":["L87M"]},"labels":{"aa":"OPG115: V105I; OPG153: A21E; OPG174: E64Q; OPG198: L87M"}},"children":[{"name":"JX878420","node_attrs":{"div":297,"accession":"JX878420","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0283"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-02-26"},"strain_display":{"value":"Democratic Republic of the Congo/JX878420/2007-02-26"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A8054-"]}}},{"name":"JX878419","node_attrs":{"div":297,"accession":"JX878419","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0275"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-02-10"},"strain_display":{"value":"Democratic Republic of the Congo/JX878419/2007-02-10"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000011","node_attrs":{"div":267,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T458-","A459-","G460-","C7756A","-140134A","-140135A","-140136C","-140137A","-140138A","-140139T","-140140T","-140141A","-140142T","-146863A","-146864T","-146884T","-146885T","-146886T","-146887A","-146888T","-146889A","-146890T","-146891T","-146892T","-146893T","-146894A","-146895T","G150568-","-169721A","-169723A","-169725A","-169726T","-179227A","C196750-","T196751-","A196752-"],"OPG159":["-124N","-125Y","-126N"]},"labels":{"aa":"OPG159: -124N, -125Y, -126N"}},"children":[{"name":"NODE_0000012","node_attrs":{"div":276,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C204A","C790T","C115912T","G148121A","A148344T","G152154A","C155631A","G169205T","C176693T","C177720T","G186892T","G196420A"],"OPG153":["P390L"],"OPG173":["V29I"],"OPG205":["R689C"],"OPG210":["R1846I"]},"labels":{"aa":"OPG153: P390L; OPG173: V29I; OPG205: R689C; OPG210: R1846I"}},"children":[{"name":"KP849471","node_attrs":{"div":287,"accession":"KP849471","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Yoshinori,N.,Muyembe,J.-J.,Kingbeni,P.M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Yoshinori,N.,Muyembe,J.-J.,Kingbeni,P.M."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"Yambuku_DRC_1985"},"date":{"value":"1985-XX-XX"},"strain_display":{"value":"Democratic Republic of the Congo/KP849471/1985-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G3975A","G12958A","A17046T","G60368A","C83195T","G85079A","G86364A","G133454A","T148337-","G150484A","-150568G","G150582T","G156302A","G180598A","C193235T","G197006T"],"OPG029":["D8E"],"OPG080":["P551S"],"OPG176":["D226N"]},"labels":{"aa":"OPG029: D8E; OPG080: P551S; OPG176: D226N"}}},{"name":"NODE_0000013","node_attrs":{"div":282,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T8510C","C16123A","C51889T","T87138C","G136499A","A146877T","T146880A","G151145A","T178510-"],"OPG027":["E85D"]},"labels":{"aa":"OPG027: E85D"}},"children":[{"name":"JX878410","node_attrs":{"div":283,"accession":"JX878410","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 06-1070"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-11-24"},"strain_display":{"value":"Democratic Republic of the Congo/JX878410/2006-11-24"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T8470C","-8471T","-148336T"]}}},{"name":"NODE_0000014","node_attrs":{"div":295,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T7058G","G16406A","G24032A","C69800T","T71738C","C79473A","G104054T","G141897A","G153208A","C162040T","C163571T","G165428A","A170972-","-178510T","A181253-","T183992C","A186633G","A189692-"],"OPG088":["A22T"],"OPG102":["P130H"],"OPG180":["A173T"],"OPG188":["L149F"],"OPG189":["A80V"],"OPG190":["G103S"],"OPG210":["T1760A"]},"labels":{"aa":"OPG088: A22T; OPG102: P130H; OPG180: A173T; OPG188: L149F; OPG189: A80V; OPG190: G103S; OPG210: T1760A"}},"children":[{"name":"JX878412","node_attrs":{"div":298,"accession":"JX878412","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 06-1076"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-11-30"},"strain_display":{"value":"Democratic Republic of the Congo/JX878412/2006-11-30"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G15850T","C99681T","C129086T"],"OPG151":["P55S"]},"labels":{"aa":"OPG151: P55S"}}},{"name":"NODE_0000015","node_attrs":{"div":296,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T6937-","G115548A"],"OPG133":["P50L"]},"labels":{"aa":"OPG133: P50L"}},"children":[{"name":"JX878411","node_attrs":{"div":296,"accession":"JX878411","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 06-1075"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-11-30"},"strain_display":{"value":"Democratic Republic of the Congo/JX878411/2006-11-30"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}},{"name":"JX878409","node_attrs":{"div":296,"accession":"JX878409","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 06-0999"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-11-09"},"strain_display":{"value":"Democratic Republic of the Congo/JX878409/2006-11-09"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000016","node_attrs":{"div":293,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G1750A","G11111A","G14622A","C25557T","C47009T","T49703C","C85076T","G140367T","-148336T","C173464T","C188051T","G190541A","C195460T"],"OPG023":["A597V"],"OPG025":["R216C"]},"labels":{"aa":"OPG023: A597V; OPG025: R216C"}},"children":[{"name":"JX878422","node_attrs":{"div":295,"accession":"JX878422","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0287"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-03-20"},"strain_display":{"value":"Democratic Republic of the Congo/JX878422/2007-03-20"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A66164C","C144356T"],"OPG084":["Q481H"]},"labels":{"aa":"OPG084: Q481H"}}},{"name":"NODE_0000017","node_attrs":{"div":294,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C187388G"]}},"children":[{"name":"JX878428","node_attrs":{"div":294,"accession":"JX878428","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0514"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-06-30"},"strain_display":{"value":"Democratic Republic of the Congo/JX878428/2007-06-30"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000018","node_attrs":{"div":296,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T8470C","-8471T","A14622G"],"OPG025":["C216R"]},"labels":{"aa":"OPG025: C216R"}},"children":[{"name":"JX878427","node_attrs":{"div":296,"accession":"JX878427","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0480"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-05-25"},"strain_display":{"value":"Democratic Republic of the Congo/JX878427/2007-05-25"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C144356-"]}}},{"name":"JX878421","node_attrs":{"div":297,"accession":"JX878421","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0286"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-03-22"},"strain_display":{"value":"Democratic Republic of the Congo/JX878421/2007-03-22"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G174812T"],"OPG204":["R94M"]},"labels":{"aa":"OPG204: R94M"}}},{"name":"JX878416","node_attrs":{"div":297,"accession":"JX878416","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0093"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-12-26"},"strain_display":{"value":"Democratic Republic of the Congo/JX878416/2006-12-26"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G50130A"],"OPG069":["D49N"]},"labels":{"aa":"OPG069: D49N"}}},{"name":"JX878415","node_attrs":{"div":296,"accession":"JX878415","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0092"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-12-26"},"strain_display":{"value":"Democratic Republic of the Congo/JX878415/2006-12-26"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}},{"name":"JX878414","node_attrs":{"div":296,"accession":"JX878414","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0046"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-12-14"},"strain_display":{"value":"Democratic Republic of the Congo/JX878414/2006-12-14"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}},{"name":"JX878413","node_attrs":{"div":296,"accession":"JX878413","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0045"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-12-14"},"strain_display":{"value":"Democratic Republic of the Congo/JX878413/2006-12-14"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}}]}]}]}]}]},{"name":"NODE_0000020","node_attrs":{"div":271,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G1319T","-46648T","G70874A","C130660T","G135598A","G144341-","-148336T","T159792C","C195891A"],"OPG001":["T86N"],"OPG001_dup":["T86N"],"OPG089":["E337K"]},"labels":{"aa":"OPG001: T86N; OPG001_dup: T86N; OPG089: E337K"}},"children":[{"name":"NODE_0000021","node_attrs":{"div":276,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["-8993A","C8994-","A56010G","C81524T","C94783T","C141329T","G148121A","G150582-","A150583-","T150584-","G150585-","A150586-"],"OPG115":["H42Y"],"OPG173":["V29I"]},"labels":{"aa":"OPG115: H42Y; OPG173: V29I"}},"children":[{"name":"NODE_0000022","node_attrs":{"div":279,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G6645T","G108249A","A133978-","A133979-","C133980-","T148343A","-173286A","-173287T","A184202C"],"OPG127":["H193Y"]},"labels":{"aa":"OPG127: H193Y"}},"children":[{"name":"KC257460","node_attrs":{"div":286,"accession":"KC257460","author":{"author":"Nakazawa,Y.,Emerson,G.L.,Carroll,D.S.,Zhao,H.,Li,Y.,Reynolds,M.G.,Karem,K.L.,Olson,V.A.,Lash,R.R.,Davidson,W.B.,Smith,S.K.,Levine,R.S.,Regnery,R.L.,Sammons,S.A.,Frace,M.A.,Mutasim,E.M.,Karsani,M.E.,Muntasir,M.O.,Babiker,A.A.,Opoka,L.,Chowdhary,V.,Damon,I.K.,Karsani,M.E.M.","value":"Nakazawa,Y.,Emerson,G.L.,Carroll,D.S.,Zhao,H.,Li,Y.,Reynolds,M.G.,Karem,K.L.,Olson,V.A.,Lash,R.R.,Davidson,W.B.,Smith,S.K.,Levine,R.S.,Regnery,R.L.,Sammons,S.A.,Frace,M.A.,Mutasim,E.M.,Karsani,M.E.,Muntasir,M.O.,Babiker,A.A.,Opoka,L.,Chowdhary,V.,Damon,I.K.,Karsani,M.E.M."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Biochemistry & Microbiology, University of Victoria, Canada"},"strain":{"value":"KC257460"},"host":{"value":"Homo sapiens"},"date":{"value":"1985-XX-XX"},"strain_display":{"value":"Democratic Republic of the Congo/KC257460/1985-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A461-","T462-","T463-","G464-","G465-","C466-","A581G","G582-","A583-","T12940-","A12941-","A21066G","G45419T","G46543A","C55215T","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","G164590A","C169530A","-170918G","G182700T","G183510-","T183511-","C183512-","C183513-","A183514-","A183515-","A183516-","A183517-","T183518-","C183519-","C183520-","G183521-","C183522-","C183523-","A183524-","C183525-","A183526-","A183527-","C183528-","T183529-","T183530-","C183531-","C183532-","C183533-","C183534-","C183535-","T183536-","A183537-","G183538-","A183539-","C183540-","C183541-","A183542-","T196627C","C196630-","T196631-","G196744-","C196745-","C196746-","A196747-","A196748-","T196749-"],"OPG153":["I370D","I371D","D372I","D373I"],"OPG189":["A420T"],"OPG197":["V36T"],"OPG210":["G449C","Q720-","N721-","P722-","P723-","Q724-","L725-","P726-","P727-","R728-","P729-","V730-"]},"labels":{"aa":"OPG153: I370D, I371D, D372I, D373I; OPG189: A420T; OPG197: V36T; OPG210: G449C, Q720-, N721-, P722-, P723-, Q724-, L725-, P726-, P727-, R728-, P729-, V730-"}}},{"name":"NODE_0000023","node_attrs":{"div":290,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C204A","G6146A","T11318C","C19628T","C33967G","T35962C","A42121C","T46648-","C126969T","C138190A","G166163A","G171413A","-173288A","-173289T","-173290A","-173291T","-173292A","-173293T","-173294A","-173295T","-173296A","-173297T","-173298A","-173299T","-173300A","-173301T","C178333T","A179227G","A179236G","C191064T","G197006T"],"OPG015":["A4V"],"OPG015_dup":["A4V"],"OPG023":["Y528C"],"OPG052":["S10T"],"OPG054":["Q12R"],"OPG155":["R101I"],"OPG191":["M1I"],"OPG199":["M142I"]},"labels":{"aa":"OPG015: A4V; OPG015_dup: A4V; OPG023: Y528C; OPG052: S10T; OPG054: Q12R; OPG155: R101I; OPG191: M1I; OPG199: M142I"}},"children":[{"name":"HM172544","node_attrs":{"div":332,"accession":"HM172544","author":{"author":"Farlow,J.,Ichou,M.A.,Huggins,J.,Ibrahim,S.,Ait Ichou,M.,Ibrahims,S.","value":"Farlow,J.,Ichou,M.A.,Huggins,J.,Ibrahim,S.,Ait Ichou,M.,Ibrahims,S."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Virology, The United States Army Medical Research Institute for Infectious Diseases (USAMRIID), USA"},"strain":{"value":"Zaire 1979-005"},"host":{"value":"Homo sapiens"},"date":{"value":"1979-XX-XX"},"strain_display":{"value":"Democratic Republic of the Congo/HM172544/1979-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G6897A","C13503T","C24978-","T30041-","C31367T","T33413-","G33447A","C38066A","C42664T","A45990T","T48341A","T50745C","G51355A","T51682C","G52016A","C52389T","C52602T","G53498A","T56271C","A71178-","G75423A","C80549T","G81722A","A82190C","T83083G","G87216A","C87303T","T97494C","C100884T","C102551A","C105412T","G105605A","G116846A","C126632T","G126942A","A135122G","G147239A","C148546T","T149979C","G152106-","C162397T","C164144T","A166358T","T169140A","C175384T","T176564C","T183716C","T189840C"],"OPG025":["A589T"],"OPG051":["T68M"],"OPG063":["R342H"],"OPG070":["V256I"],"OPG071":["A314V","A613T","A684T","T808M"],"OPG095":["M207I"],"OPG105":["K355N","L653R"],"OPG109":["M715I"],"OPG120":["A289T"],"OPG122":["L42I"],"OPG124":["H122Y","S186N"],"OPG148":["S216L"],"OPG174":["A284T"],"OPG178":["G200-"],"OPG188":["H268Y"],"OPG189":["A271V"],"OPG191":["Q66H"]},"labels":{"aa":"OPG025: A589T; OPG051: T68M; OPG063: R342H; OPG070: V256I; OPG071: A314V, A613T, A684T, T808M; OPG095: M207I; OPG105: K355N, L653R; OPG109: M715I; OPG120: A289T; OPG122: L42I; OPG124: H122Y, S186N; OPG148: S216L; OPG174: A284T; OPG178: G200-; OPG188: H268Y; OPG189: A271V; OPG191: Q66H"}}},{"name":"DQ011155","node_attrs":{"div":290,"accession":"DQ011155","author":{"author":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S.","value":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Centers for Disease Control and Prevention, National Center for Infectious Diseases"},"strain":{"value":"Zaire_1979-005"},"host":{"value":"Homo sapiens"},"date":{"value":"1978-XX-XX"},"strain_display":{"value":"Democratic Republic of the Congo/DQ011155/1978-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000024","node_attrs":{"div":293,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T7092-","T7093-","A7094-","C7095-","A7096-","G7097-","T7098-","A7099-","T7100-","A7101-","T7102-","A7103-","C7104-","G7105-","T7106-","T7107-","A7108-","T7109-","T7110-","C8249T","C38214T","C52909T","C63123T","C82622T","C85325T","C85869T","C101013T","G109883A","G117995A","A118781G","C123585T","A125829G","G133473T","G146819-","T146866G","C165490T","C165639A","A184066G","G197132-","A197133-","A197149-","G197150-","A197151-","G197152-","T197153-","T197154-","T197155-","C197156-","C197157-","T197158-","A197159-","C197160-","G197161-","G197162-"],"OPG056":["S274N"],"OPG120":["V246M"],"OPG190":["A173D"],"OPG210":["K904R"]},"labels":{"aa":"OPG056: S274N; OPG120: V246M; OPG190: A173D; OPG210: K904R"}},"children":[{"name":"MT724770","node_attrs":{"div":295,"accession":"MT724770","author":{"author":"Marien,J.,Laudisoit,A.,Patrono,L.V.,Calvignac-Spencer,S.,Leendertz,F.,Leirs,H.,Verheyen,E.","value":"Marien,J.,Laudisoit,A.,Patrono,L.V.,Calvignac-Spencer,S.,Leendertz,F.,Leirs,H.,Verheyen,E."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Biology, Universiteit Antwerpen, Belgium"},"strain":{"value":"MT724770"},"host":{"value":"Crocidura littoralis"},"date":{"value":"2014-01-01"},"strain_display":{"value":"Democratic Republic of the Congo/MT724770/2014-01-01"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C204A","C133072T","T136555-","G136558C","-150582G","-150583A","-150584T","-150585G","-150586A","C159210T","G189214A"],"OPG005":["A6T"]},"labels":{"aa":"OPG005: A6T"}}},{"name":"NODE_0000025","node_attrs":{"div":294,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T7090-","T7091-","G7111-","T7112-","C7113-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T180483A"],"OPG159":["N124-","Y125-","N126-"]},"labels":{"aa":"OPG159: N124-, Y125-, N126-"}},"children":[{"name":"MN702449","node_attrs":{"div":294,"accession":"MN702449","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702449"},"host":{"value":"Homo sapiens"},"date":{"value":"2016-01-02"},"strain_display":{"value":"Central African Republic/MN702449/2016-01-02"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G146866T","T197117A","C197118G","T197121G","A197122T","T197123A","C197127A","A197129T","T197136A","T197138C","A197142T","C197144T","T197166A","G197167T"]}}},{"name":"MN702446","node_attrs":{"div":297,"accession":"MN702446","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702446"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-04-14"},"strain_display":{"value":"Central African Republic/MN702446/2018-04-14"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A8054-","G10673T","T37120-","G42785A","C179154T","A179162C","-179163C","-179164T","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A181253-","C181732G"],"OPG022":["D62E"],"OPG063":["P302S"],"OPG210":["T126S"]},"labels":{"aa":"OPG022: D62E; OPG063: P302S; OPG210: T126S"}}},{"name":"NODE_0000026","node_attrs":{"div":299,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["A8054-","G18952A","G87276A","C127584T","T148336-","T148337-","A148344T","A151042G","-197132G","-197133A","-197149A","-197150G","-197151A","-197152G","-197153T","-197154T","-197155T","-197156C","-197157C","-197158T","-197159A","-197160C","-197161G","-197162G"],"OPG149":["A130V"]},"labels":{"aa":"OPG149: A130V"}},"children":[{"name":"MN702445","node_attrs":{"div":299,"accession":"MN702445","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702445"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-02-06"},"strain_display":{"value":"Central African Republic/MN702445/2017-02-06"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","G197006T"]}}},{"name":"MN702444","node_attrs":{"div":299,"accession":"MN702444","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702444"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-02-06"},"strain_display":{"value":"Central African Republic/MN702444/2017-02-06"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000027","node_attrs":{"div":272,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G12632A","A146877T","T146880A"],"OPG023":["A90V"]},"labels":{"aa":"OPG023: A90V"}},"children":[{"name":"KJ642613","node_attrs":{"div":284,"accession":"KJ642613","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"KJ642613"},"date":{"value":"1970-XX-XX"},"strain_display":{"value":"Democratic Republic of the Congo/KJ642613/1970-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A581G","G582-","A583-","G7469A","C8249T","C13298T","C31628T","-41935T","C50527-","C50528-","T50529-","G50530-","C50531-","A50532-","T50533-","C50534-","T50535-","T50536-","A50537-","T50538-","T50539-","A50540-","G58413A","G63150A","C64611T","G66698T","C79369T","C111519T","G133968A","G144316T","G150582T","A150634-","A150635-","T178641-","T196627C","C196630-","T196631-"],"OPG083":["V36I"],"OPG153":["I371D"]},"labels":{"aa":"OPG083: V36I; OPG153: I371D"}}},{"name":"NODE_0000028","node_attrs":{"div":290,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G907A","G3308T","G11575A","T15747-","G31211A","G35067A","G37230T","T57906C","G60984A","G62421A","C87507T","C100648G","T101111C","G136039T","C137054T","A148344T","C154681T","G180556T","G181036A","G189591A","C193902A","C196303T"],"OPG005":["M131I"],"OPG047":["D478N"],"OPG056":["T602N"],"OPG119":["T88R"],"OPG120":["H213R"],"OPG153":["R205H"]},"labels":{"aa":"OPG005: M131I; OPG047: D478N; OPG056: T602N; OPG119: T88R; OPG120: H213R; OPG153: R205H"}},"children":[{"name":"DQ011154","node_attrs":{"div":292,"accession":"DQ011154","author":{"author":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S.","value":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S."},"country":{"value":"Republic of the Congo"},"institution":{"value":"National Center for Infectious Diseases, Centers for Disease Control and Prevention (US CDC), USA"},"strain":{"value":"Congo_2003_358"},"host":{"value":"Homo sapiens"},"date":{"value":"2003-XX-XX"},"strain_display":{"value":"Republic of the Congo/DQ011154/2003-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C204A","G140147A","T140154C","C150750T","C188925A","G197006T"],"OPG159":["C127Y"]},"labels":{"aa":"OPG159: C127Y"}}},{"name":"NODE_0000029","node_attrs":{"div":293,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["A5646G","T6219-","G24996A","C149078T","A189040-","A190994-","T191564C"],"OPG015":["C171R"],"OPG015_dup":["C171R"]},"labels":{"aa":"OPG015: C171R; OPG015_dup: C171R"}},"children":[{"name":"MN702451","node_attrs":{"div":300,"accession":"MN702451","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702451"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-04-14"},"strain_display":{"value":"Central African Republic/MN702451/2017-04-14"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G39626A","A65771T","G93521T","T146865A","A146868T","-150568G","G151440A","T155635-","T155636-","A155637-","G155638-","A155639-","T155640-","A155641-","G155642-","C165304T","C167244T","G171695A","C179163T","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","A179236G","T197117A","C197118G","T197121G","A197122T","T197123A","C197127A","A197129T","G197132-","A197133-","T197134-","T197135-","T197136-","T197137-","T197138-","C197139-","C197143T","C197147-","T197148-","A197149-","G197150-","A197151-","G197152-","T197153-","T197154-","T197155-","C197156-","C197157-","T197158-","A197159-","C197160-","G197161-","G197162-","T197163-","C197164-","G197165-","T197166-","G197167-","G197168-","G197169-","T197170-","C197171-","A197172-","C197173-","A197174-","C197175-","A197176-","T197177-","T197178-","T197179-","T197182C"],"OPG192":["H172Y"]},"labels":{"aa":"OPG192: H172Y"}}},{"name":"KP849469","node_attrs":{"div":295,"accession":"KP849469","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Yoshinori,N.,Muyembe,J.-J.,Kingbeni,P.M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Yoshinori,N.,Muyembe,J.-J.,Kingbeni,P.M."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"Boende_DRC_2008"},"date":{"value":"2008-XX-XX"},"strain_display":{"value":"Democratic Republic of the Congo/KP849469/2008-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A10459T","T10460-","A10461-","G135460T","G197006T"]}}}]},{"name":"NODE_0000030","node_attrs":{"div":293,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["A134C","C33905T","G40666C","T143617C","T146877A","A146880T","G150582-","A150583-","T150584-","G150585-","A150586-","T189889-","T189890-","A189891-","T189892-","T189893-","A189894-","C189895-","G189896-","T189897-","G189898-","A189899-","A189900-","G189901-","A189902-","T189903-","G189904-","A189905-","T189906-","A189907-","T189908-","C189909-","A189910-","T189911-","T189912-","A189913-","A189914-","A189915-","C189916-","C189917-","A189918-","A189919-","C189920-","A189921-","T189922-","T189923-","G189924-","A189925-","G189926-","A189927-","T189928-","T189929-","G189930-","G189931-","C189932-","T189933-","C189934-","T189935-","T189936-","A189937-","T189938-","G189939-","T189940-","T189941-","A189942-","G189943-","C189944-","T189945-","G189946-","G189947-","A189948-","T189949-","T189950-","G189951-","A189952-","A189953-","T189954-","T189955-","A189956-","C189957-","T189958-","G189959-","T189960-","A189961-","A189962-","T189963-","A189964-","A189965-","A189966-","T189967-","G189968-","C189969-","A189970-","T189971-","C189972-","G189973-","A189974-","G189975-","T189976-","A189977-","T189978-","A189979-","G189980-","A189981-","G189982-","G189983-","G189984-","A189985-","T189986-","A189987-","T189988-","A189989-","G189990-","C189991-","A189992-","A189993-","T189994-","T189995-","C189996-","T189997-","C189998-","G189999-","A190000-","T190001-","A190002-","A190003-","T190004-","A190005-","G190006-","T190007-","C190008-","A190009-","T190010-","G190011-","C190012-","A190013-","A190014-","T190015-","A190016-","T190017-","T190018-","T190019-","G190020-","A190021-","A190022-","T190023-","G190024-","A190025-","G190026-","A190027-","C190028-","T190029-","G190030-","A190031-","T190032-","A190033-","A190034-","T190035-","T190036-","T190037-","A190038-","G190039-","G190040-","T190041-","A190042-","A190043-","T190044-","A190045-","C190046-","A190047-","G190048-","T190049-","A190050-","C190051-","T190052-","A190053-","C190054-","A190055-","C190056-","A190057-","C190058-","A190059-","T190060-","A190061-","T190062-","C190063-","T190064-","T190065-","T190066-","C190067-","T190068-","A190069-","G190070-","A190071-","T190072-","T190073-","A190074-","T190075-","A190076-","T190077-","A190078-","T190079-","C190080-","G190081-","T190082-","T190083-","A190084-","A190085-","A190086-","A190087-","A190088-","T190089-","C190090-","T190091-","G190092-","T190093-","A190094-","A190095-","G190096-","A190097-","G190098-","G190099-","T190100-","A190101-","T190102-","A190103-","T190104-","T190105-","T190106-","C190107-","T190108-","C190109-","A190110-","T190111-","A190112-","A190113-","G190114-","T190115-","A190116-","T190117-","C190118-","C190119-","A190120-","C190121-","T190122-","G190123-","T190124-","G190125-","T190126-","A190127-","A190128-","T190129-","A190130-","T190131-","T190132-","A190133-","T190134-","T190135-","A190136-","A190137-","T190138-","G190139-","G190140-","A190141-","T190142-","A190143-","T190144-","A190145-","T190146-","A190147-","G190148-","A190149-","T190150-","A190151-","A190152-","C190153-","A190154-","C190155-","A190156-","A190157-","T190158-","A190159-","G190160-","G190161-","G190162-","A190163-","C190164-","T190165-","A190166-","A190167-","T190168-","A190169-","G190170-","T190171-","A190172-","T190173-","T190174-","G190175-","T190176-","A190177-","A190178-","A190179-","A190180-","G190181-","A190182-","T190183-","A190184-","T190185-","A190186-","A190187-","T190188-","C190189-","G190190-","A190191-","C190192-","T190193-","A190194-","T190195-","T190196-","T190197-","G190200-","T190201-","A190202-","C190203-","A190204-","T190205-","A190206-","T190207-","C190208-","C190209-","A190210-","G190211-","A190212-","T190213-","A190214-","T190215-","C190216-","T190217-","A190218-","T190219-","A190220-","T190221-","T190222-","C190223-","C190224-","T190225-","A190226-","C190227-","T190228-","A190229-","G190230-","T190231-","T190232-","T190233-","G190234-","C190235-","T190236-","G190237-","C190238-","G190239-","T190240-","A190241-","G190242-","T190243-","T190244-","G190245-","C190246-","A190247-","T190248-","C190249-","A190250-","T190251-","T190252-","G190253-","A190254-","T190255-","A190256-","T190257-","G190258-","C190259-","A190260-","T190261-","G190262-","A190263-","T190264-","T190265-","T190266-","A190267-","T190268-","C190269-","A190270-","G190271-","G190272-","A190273-","T190274-","T190275-","C190276-","A190277-","G190278-","A190279-","G190280-","A190281-","T190282-","G190283-","A190284-","A190285-","T190286-","T190287-","A190288-","C190289-","T190290-","A190291-","A190292-","G190293-","T190294-","A190295-","A190296-","A190297-","C190298-","T190299-","A190300-","C190301-","A190302-","A190303-","T190304-","C190305-","C190306-","C190307-","A190308-","C190309-","A190310-","A190311-","T190312-","A190313-","A190314-","G190315-","T190316-","A190317-","A190318-","G190319-","A190320-","A190321-","T190322-","C190323-","A190324-","A190325-","A190326-","T190327-","A190328-","T190329-","C190330-","A190331-","A190332-","A190333-","A190334-","A190335-","C190336-","T190337-","C190338-","A190339-","C190340-","T190341-","T190342-","T190343-","T190344-","G190345-","A190346-","T190347-","T190348-","T190349-","T190350-","T190351-","C190352-","T190353-","A190354-","G190355-","T190356-","C190357-","T190358-","T190359-","A190360-","A190361-","G190362-","T190363-","A190364-","A190365-","T190366-","A190367-","C190368-","A190369-","T190370-","A190371-","T190372-","A190373-","T190374-","T190375-","T190376-","A190377-","T190378-","T190379-","A190380-","A190381-","T190382-","A190383-","G190384-","A190385-","C190386-","C190387-","T190388-","A190389-","T190390-","G190391-","A190392-","A190393-","A190394-","T190395-","A190396-","A190397-","A190398-","A190399-","A190400-","A190401-","G190403-","T190404-","T190405-","A190406-","A190407-","C190408-","A190409-","A190410-","T190411-","G190412-","G190413-","A190414-","T190415-","T190416-","C190417-","G190418-","C190419-","G190420-","T190421-","A190422-","T190423-","A190424-","G190425-","C190426-","T190427-","A190428-","T190429-","T190430-","T190431-","A190432-","C190433-","G190434-","T190435-","A190436-","T190437-","T190438-","A190439-","G190440-","T190441-","A190442-","T190443-","C190444-","G190445-","G190446-","C190447-","A190448-","T190449-","C190450-","T190451-","C190452-","T190453-","T190454-","T190455-","T190456-","G190457-","T190458-","A190459-","T190460-","C190461-","T190462-","T190463-","G190464-","T190465-","T190466-","A190467-","A190468-","T190469-","T190470-","G190471-","T190472-","C190473-","A190474-","C190475-","A190476-","A190477-","A190478-","C190479-","T190480-","A190481-","G190482-","T190483-","A190484-","C190485-","A190486-","T190487-","T190488-","A190489-","C190490-","T190491-","T190492-","C190493-","A190494-","A190495-","T190496-","C190497-","T190498-","G190499-","A190500-","A190501-","A190502-","A190503-","T190504-","A190505-","A190506-","A190507-","T190508-","G190509-","G190510-","T197076G"],"OPG052":["A31T"]},"labels":{"aa":"OPG052: A31T"}},"children":[{"name":"NODE_0000031","node_attrs":{"div":297,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G36971A","G124667A","G125413A","G176109A"],"OPG055":["S38L"],"OPG145":["A241T"],"OPG146":["A76V"],"OPG205":["D152N"]},"labels":{"aa":"OPG055: S38L; OPG145: A241T; OPG146: A76V; OPG205: D152N"}},"children":[{"name":"JX878429","node_attrs":{"div":297,"accession":"JX878429","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0662"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-09-04"},"strain_display":{"value":"Democratic Republic of the Congo/JX878429/2007-09-04"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}},{"name":"JX878425","node_attrs":{"div":297,"accession":"JX878425","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0354"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-04-20"},"strain_display":{"value":"Democratic Republic of the Congo/JX878425/2007-04-20"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-144341G"]}}}]},{"name":"NODE_0000032","node_attrs":{"div":296,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T18789C","G58263T","T73298C"],"OPG031":["T14A"]},"labels":{"aa":"OPG031: T14A"}},"children":[{"name":"JX878407","node_attrs":{"div":298,"accession":"JX878407","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 06-0950"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-10-09"},"strain_display":{"value":"Democratic Republic of the Congo/JX878407/2006-10-09"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C15207T","C47598T"],"OPG025":["A21T"]},"labels":{"aa":"OPG025: A21T"}}},{"name":"NODE_0000033","node_attrs":{"div":297,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C15349A"]}},"children":[{"name":"JX878424","node_attrs":{"div":297,"accession":"JX878424","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0338"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-03-25"},"strain_display":{"value":"Democratic Republic of the Congo/JX878424/2007-03-25"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A179227G","A179236G"]}}},{"name":"JX878423","node_attrs":{"div":298,"accession":"JX878423","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0337"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-03-25"},"strain_display":{"value":"Democratic Republic of the Congo/JX878423/2007-03-25"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C108244T"],"OPG127":["M194I"]},"labels":{"aa":"OPG127: M194I"}}}]}]}]},{"name":"NODE_0000034","node_attrs":{"div":291,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["A159953T","A179164-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","A179236G","T197076G"]}},"children":[{"name":"NODE_0000035","node_attrs":{"div":294,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C4584T","T55501C","A168328C","C179163T","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG074":["Y542C"],"OPG195":["K33N"]},"labels":{"aa":"OPG074: Y542C; OPG195: K33N"}},"children":[{"name":"MN702453","node_attrs":{"div":294,"accession":"MN702453","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702453"},"host":{"value":"Homo sapiens"},"date":{"value":"2001-08-11"},"strain_display":{"value":"Central African Republic/MN702453/2001-08-11"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}},{"name":"MN702452","node_attrs":{"div":295,"accession":"MN702452","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702452"},"host":{"value":"Homo sapiens"},"date":{"value":"2010-08-10"},"strain_display":{"value":"Central African Republic/MN702452/2010-08-10"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C164169T"]}}}]},{"name":"NODE_0000036","node_attrs":{"div":292,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G42564A","-179164G","-179172T"]}},"children":[{"name":"NODE_0000037","node_attrs":{"div":295,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C6624-","G6625-","A6626-","G6627-","T6628-","A6629-","G6630-","T6631-","A6632-","A6633-","C6634-","T6635-","T6636-","C6637-","T6638-","A6639-","A6640-","T6641-","A6642-","A6643-","A6644-","G6645-","A6646-","C6647-","T6648-","T6649-","G6650-","A6651-","T6652-","A6653-","T6654-","C6655-","A6656-","T6657-","T6658-","A6659-","T6660-","C6661-","A6662-","T6663-","A6664-","T6665-","G6666-","T6667-","T6668-","T6669-","G6670-","A6671-","T6672-","C6673-","G6674-","T6675-","C6676-","A6677-","T6678-","A6679-","G6680-","T6681-","T6682-","A6683-","A6684-","T6685-","A6686-","G6687-","T6688-","G6689-","T6690-","G6691-","G6692-","C6693-","T6694-","A6695-","A6696-","A6697-","T6698-","G6699-","G6700-","T6701-","A6702-","C6703-","T6704-","G6705-","T6706-","T6707-","A6708-","A6709-","T6710-","A6711-","A6712-","G6713-","T6714-","T6715-","T6716-","A6717-","T6718-","A6719-","G6720-","A6721-","C6722-","A6723-","A6724-","T6725-","A6726-","T6727-","C6728-","A6729-","T6730-","A6731-","G6732-","T6733-","C6744-","A6745-","G6746-","A6747-","A6748-","T6749-","T6750-","A6751-","G6752-","A6753-","T6754-","T6755-","A6756-","T6757-","T6758-","T6759-","T6760-","T6761-","T6762-","T6763-","A6764-","A6765-","A6766-","T6767-","A6768-","C6769-","T6770-","G6771-","A6772-","T6773-","C6774-","C6775-","T6776-","C6777-","A6778-","C6779-","A6780-","A6781-","T6782-","T6783-","C6784-","C6785-","G6786-","T6787-","G6788-","A6789-","T6790-","G6791-","T6792-","A6793-","G6794-","C6795-","A6796-","G6797-","T6798-","A6799-","G6800-","T6801-","T6802-","G6803-","G6804-","T6805-","G6806-","C6807-","A6808-","T6809-","G6810-","G6811-","T6812-","C6813-","T6814-","A6815-","T6816-","A6817-","T6818-","C6819-","G6820-","T6821-","T6822-","A6823-","A6824-","A6825-","A6826-","T6827-","G6828-","A6835G","T6836G","G6843T","T6846G","C6848G","G6850-","A6851-","C6852-","G6853-","T6854-","G6855-","G6856-","A6857-","G6858-","T6859-","A6860-","C6861-","A6862-","G6863-","A6864-","A6865-","T6866-","T6867-","T6868-","T6869-","C6870-","G6871-","A6872-","T6873-","T6874-","A6875-","A6876-","T6877-","G6878-","A6879-","G6880-","T6881-","T6882-","C6883-","A6884-","T6885-","G6886-","G6887-","T6888-","A6889-","A6890-","G6891-","G6892-","A6893-","A6894-","G6895-","G6896-","G6897-","C6898-","A6899-","A6900-","A6901-","T6902-","G6903-","T6904-","A117317G","G150585-","G150620A","G150621A","A150634-","A150635-","A169721-","C169722-","A169723-","G169724-","A169725-","T169726-","G171695A","-173286A","-173287T","-173288A","-173289T","G174029A","-174537G","-174538A","-174539T","-174540G","-174541A","-174542A"],"OPG197":["T18-","D19-"]},"labels":{"aa":"OPG197: T18-, D19-"}},"children":[{"name":"MN702448","node_attrs":{"div":296,"accession":"MN702448","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702448"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-03-07"},"strain_display":{"value":"Central African Republic/MN702448/2018-03-07"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G168741A"],"OPG195":["R171K"]},"labels":{"aa":"OPG195: R171K"}}},{"name":"MN702447","node_attrs":{"div":295,"accession":"MN702447","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702447"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-03-20"},"strain_display":{"value":"Central African Republic/MN702447/2018-03-20"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000038","node_attrs":{"div":296,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G7410A","A146863-","T146864-","T146866-","G169138A","A171639T","G186880A"],"OPG199":["T218S"],"OPG210":["R1842H"]},"labels":{"aa":"OPG199: T218S; OPG210: R1842H"}},"children":[{"name":"MN702450","node_attrs":{"div":305,"accession":"MN702450","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702450"},"host":{"value":"Homo sapiens"},"date":{"value":"2016-01-01"},"strain_display":{"value":"Central African Republic/MN702450/2016-01-01"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C6388A","G8888A","C47932A","G100885T","G108940A","C122824A","T138194A","T146865-","T146867-","A146868-","T146869-","A146870-","T146871-","G172951T","A186911G"],"OPG128":["A39V"],"OPG143":["K164N"],"OPG155":["T100S"],"OPG210":["I1852M"]},"labels":{"aa":"OPG128: A39V; OPG143: K164N; OPG155: T100S; OPG210: I1852M"}}},{"name":"OQ729808","node_attrs":{"div":305,"accession":"OQ729808","author":{"author":"Lee,T.Y.,Hwang,Y.-H.,Yun,M.-R.,Kim,Y.-J.,Kim,D.","value":"Lee,T.Y.,Hwang,Y.-H.,Yun,M.-R.,Kim,Y.-J.,Kim,D."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Korea National Institute of Health, Division of Infectious Disease Vaccine Research"},"strain":{"value":"MPXV/COD/2023/172V"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-XX-XX"},"strain_display":{"value":"Democratic Republic of the Congo/OQ729808/2022-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A134C","C29763T","G45818A","G70364A","G111683A","C131908A","G133359A","G139736A","-146866G","T146877A","A146880T","T148344A","G179164A","T179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","G179236A","G188460A"],"OPG089":["D167N"],"OPG130":["P74S"],"OPG158":["R12C"]},"labels":{"aa":"OPG089: D167N; OPG130: P74S; OPG158: R12C"}}}]}]}]}]}]}]}]}]}]},{"name":"NODE_0000039","node_attrs":{"div":308,"clade_membership":{"value":"II"}},"branch_attrs":{"mutations":{"nuc":["C466T","A630C","C720T","G1093A","T1201C","G1504A","G2086T","A2391C","C2554T","G4836T","A5751G","G6076A","G6146A","T6904C","C7005T","C7648T","C7810T","G8066A","G8694T","C8923T","G9161T","G9376A","A9509T","A9698G","C10992T","G12003A","A12324C","G12352A","G12380A","G12418T","C13135T","A13223C","A13348G","C13995T","T13999G","T14091C","C14431T","A15602G","C15794T","G16393T","G16406A","A16581G","-16608G","G16634A","T17496C","C17800T","C18478A","C18953T","C19290T","C19392A","C19457T","G19475A","G20605A","G21034A","G21191A","T22928C","G23080T","-23171A","G24032A","C24179T","C25856T","C27614T","C27949T","T28532A","G28548A","T28710C","G31102A","A31144G","C32867T","A33102T","C33656A","C33708A","C34301A","G35613A","C36049T","T37170C","C39248T","G40558T","C40565T","T40937C","T41967C","A42516T","G42769A","C43751T","T44972A","G45500A","G45584A","A45637C","G46217A","C46417T","C46427A","T47140G","C47181T","T47735G","G49223T","T49994C","A50595C","G52354T","C52684T","C52938T","A52989C","G53156A","A53257G","C55188T","G55203A","C56531T","G58035T","C58131T","C58965T","G59046A","T59488C","G59709A","G60874C","C61056A","C62823T","C63156T","C63303T","A63976G","G64465A","A65352T","G65663A","G66263A","C66761A","C67245T","C67550T","T69675G","G72261A","G73076A","G75790A","C76123T","G76198A","G76648A","G76911A","C78461A","G78641A","G78942A","T79267C","A79502C","G79829A","T81989C","C83360T","C83843T","G84395A","T85763C","T86502G","T87584C","G88773A","G90493A","C90891T","G91347A","G91489T","C93356T","C95469T","T96651C","A97572G","A99234G","C100341T","A102971C","G103051A","G103424T","C106857A","G107511T","G108793A","G110828T","C111539T","G111545A","T111591A","A113747G","G114458A","C116583T","T116643A","A116660G","A117014G","G117725T","C118520T","A120174C","C120363T","G121082A","A121453C","G121711A","C122049T","A122422G","C124687T","A125047G","G125334A","G125556A","G126923T","C126969T","C127859T","G128546T","G130030A","C131806T","C132118T","C133280T","G133328A","G133455A","T134233A","G134491A","C134765T","G136190T","C136486A","G136596A","G137026T","C137377T","C137731T","G137925A","C138513T","A138654G","C138746T","G139285T","C139539T","G139771A","C139874T","G143108A","C143392T","T143997C","C144049T","C145074T","G145088T","C145336T","G145523T","C145551A","T146098G","G146215A","G146434A","T146446C","G147904T","T150132C","A150153G","C150488T","C150513T","G150545A","G150780A","G151320A","A151341C","G151923A","A152967T","G153645A","T154702C","T154975C","A155479C","G155843A","G158787T","G159351A","C159530T","T159741C","G159780A","T160924A","T161519A","T162639C","G162720A","A165006G","T165691C","C166934T","C168185T","C168588-","T168769C","A168987C","G169081A","C169142T","G169353A","-169721T","G169772-","C170037T","G170335A","A172087-","G172304A","G173102A","G173472A","T173569C","G173974A","A174301G","T175964C","T176453C","A176701G","A176715G","C177517T","C177724T","C178237T","C178311A","A178639G","A178791G","A179023G","T179478C","C179538A","T179589G","C179690T","C180197T","A181364T","C182033T","C182348A","G183491A","C183718T","C183920T","C184286T","A185268G","G185762A","C185900T","C186077T","G186466T","G186505A","C187345T","G187498A","C187839T","A187914G","C187964T","C188537T","A188726G","C188747A","G188812A","C189909A","A190154G","T190404G","G190596T","T190648A","G191051A","C191064T","A191401G","T191459C","C192374A","-192471C","T194819G","C195124A","C195706T","A196009G","C196117T","G196490A","G196744A"],"OPG002":["S121A"],"OPG002_dup":["S121A"],"OPG015":["A4V","F136L"],"OPG015_dup":["A4V","F136L"],"OPG016":["A63S","V80E"],"OPG021":["I38V"],"OPG023":["A174V","S193A","H300Y","E637K"],"OPG024":["G32S"],"OPG025":["K393E","V425I"],"OPG029":["R146C"],"OPG030":["D12N","N113S"],"OPG031":["E117D"],"OPG034":["R205L"],"OPG036":["P11S"],"OPG037":["R415C"],"OPG038":["P27H","I78V"],"OPG043":["A3T"],"OPG044":["L148M"],"OPG045":["T185A"],"OPG049":["V17E"],"OPG056":["Y622C"],"OPG059":["L26I"],"OPG063":["A307V"],"OPG064":["S88A"],"OPG065":["D23N"],"OPG066":["R83K","N97H"],"OPG068":["E341D"],"OPG071":["T428I","S484A","V501I"],"OPG074":["D199N"],"OPG079":["Y45C"],"OPG080":["E321D","S382C"],"OPG084":["T211S"],"OPG085":["A328T","V591F"],"OPG096":["M68I"],"OPG100":["Q152K"],"OPG101":["A153T"],"OPG102":["V249I"],"OPG109":["T622A"],"OPG111":["V77I"],"OPG112":["R34H"],"OPG130":["A122T"],"OPG135":["E90V"],"OPG145":["R463Q"],"OPG148":["S313I"],"OPG150":["E256D"],"OPG153":["H358Y","P493Q"],"OPG154":["R107H"],"OPG156":["S42Y","A222T"],"OPG157":["V24M"],"OPG159":["A2T","S36L"],"OPG164":["V111I"],"OPG165":["L161S"],"OPG167":["S107Y","V112I"],"OPG170":["I111M"],"OPG172":["D160Y"],"OPG176":["S227L"],"OPG178":["V139I"],"OPG185":["T205I"],"OPG187":["*300K"],"OPG195":["S120-"],"OPG197":["T18S"],"OPG198":["V100I"],"OPG200":["G52D"],"OPG205":["Y349C","S354G","A621V","A690V"],"OPG208":["T142I","A311V"],"OPG210":["L3F","N331K","A788V","T1305A","R1704L","G1717D"]},"labels":{"aa":"OPG002: S121A; OPG002_dup: S121A; OPG015: A4V, F136L; OPG015_dup: A4V, F136L; OPG016: A63S, V80E; OPG021: I38V; OPG023: A174V, S193A, H300Y, E637K; OPG024: G32S; OPG025: K393E, V425I; OPG029: R146C; OPG030: D12N, N113S; OPG031: E117D; OPG034: R205L; OPG036: P11S; OPG037: R415C; OPG038: P27H, I78V; OPG043: A3T; OPG044: L148M; OPG045: T185A; OPG049: V17E; OPG056: Y622C; OPG059: L26I; OPG063: A307V; OPG064: S88A; OPG065: D23N; OPG066: R83K, N97H; OPG068: E341D; OPG071: T428I, S484A, V501I; OPG074: D199N; OPG079: Y45C; OPG080: E321D, S382C; OPG084: T211S; OPG085: A328T, V591F; OPG096: M68I; OPG100: Q152K; OPG101: A153T; OPG102: V249I; OPG109: T622A; OPG111: V77I; OPG112: R34H; OPG130: A122T; OPG135: E90V; OPG145: R463Q; OPG148: S313I; OPG150: E256D; OPG153: H358Y, P493Q; OPG154: R107H; OPG156: S42Y, A222T; OPG157: V24M; OPG159: A2T, S36L; OPG164: V111I; OPG165: L161S; OPG167: S107Y, V112I; OPG170: I111M; OPG172: D160Y; OPG176: S227L; OPG178: V139I; OPG185: T205I; OPG187: *300K; OPG195: S120-; OPG197: T18S; OPG198: V100I; OPG200: G52D; OPG205: Y349C, S354G, A621V, A690V; OPG208: T142I, A311V; OPG210: L3F, N331K, A788V, T1305A, R1704L, G1717D","clade":"clade II"}},"children":[{"name":"NODE_0000040","node_attrs":{"div":395,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["G580T","C4693-","T6432G","A6448-","A6475-","A6481G","C6486G","A6494G","A6496G","T6521-","T6525A","A6529C","A6538G","C6547A","C6552T","G6557T","G6577A","A6597-","G6613A","A6620-","G6625-","C6647-","G6674T","G6687-","T6698-","C6703-","T6704-","C6722G","A6747-","T6758-","T6801A","G6810-","T6814G","A6823C","T6836-","C6852A","G6855-","T6874-","A6922-","A6959-","G6977-","G6979C","G6987-","G6992A","A7000-","C7014T","G7021T","C7024T","T7033A","A7041C","T7043G","A7052G","C7053A","A7059G","T7075C","G7078A","A7579-","C7864T","T8015C","A8143G","G8841A","T9054C","A11365G","C11745T","G12947A","C18109T","T19324A","A21111-","G22308A","C23190T","C23747T","G23966A","G24232-","C24233-","A24234-","C24977T","C25368-","C29203A","C30510T","G30699T","C31454A","G32326A","C35859T","C36732T","A42426G","A54013G","G55750A","G58482T","A70398C","G76393A","G77451A","C79658T","G80435T","G84373A","C85145T","A86916G","G87055A","C89607T","G89869A","G90034A","A91246-","A91247-","T91248-","G91249-","G91250-","A91251-","G91737A","G93422A","G94404T","G97371A","C99287T","G99587A","G100967A","A104985G","G106460T","G107366T","G125514T","T130846C","A131548G","T133086C","C133178-","C133182-","C133184-","C133539T","G133682A","G136446A","T136641C","A137515G","G140772A","G142337A","A146877-","T146878-","T146879-","T146880-","T146881-","A146882-","T146883-","A147926T","A148124G","C148542T","A150569-","T150570-","A150571-","T150572-","G150573-","A150574-","T150575-","G150576-","G150577-","A150578-","T150579-","A150580-","T150581-","G150582-","A150583-","T150584-","G150585-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G150603-","A150604-","T150605-","A150606-","T150607-","G150608-","A150609-","T150610-","G150611-","C153210A","G153894A","C156081T","C156162A","C156414-","G156448A","G156549-","C157280T","G157688-","C157689-","G157690-","G157693-","C158981T","G159964T","C160120T","G161760A","T166103-","T166104-","A166105-","A166106-","T166107-","A166108-","A166109-","T166110-","T166111-","A166112-","A166113-","T166114-","A166115-","A166116-","T168446-","A168447-","A169574G","A169763-","C169764-","A169765-","A169767-","-169772A","G169814-","A169815-","A169816-","G170283A","G170918-","G171068A","T172524C","T172667-","T173283-","A173284-","T173285-","G173318-","G173544A","G173641A","G175396A","A177073G","C178285T","T179072-","G179076-","C179423T","G181076A","C181117-","C181118-","C182411A","C182600T","C183466A","-187080T","G187398-","T187399-","A187400-","C187401-","C189273T","G192517-","C196630A","A197082G"],"OPG023":["D386N"],"OPG040":["E37D","A168T"],"OPG045":["E20D"],"OPG047":["L166I","D229N"],"OPG049":["P276S"],"OPG055":["A118T"],"OPG074":["S459F"],"OPG089":["E178A"],"OPG102":["H192Y"],"OPG105":["S1083N"],"OPG108":["A2V"],"OPG110":["V80I","A135T"],"OPG113":["A3T"],"OPG118":["A281V","G381D"],"OPG120":["A261V"],"OPG123":["V29A"],"OPG125":["H97N","L399I"],"OPG153":["T343A","I370-","I371-","H408Y"],"OPG163":["V46I"],"OPG172":["D167V"],"OPG173":["T30A"],"OPG174":["C285Y"],"OPG185":["T22I"],"OPG195":["Y73-","D74-","Q75-","C76-","T77-","E78-","P79-","H80-","D81-","F82-","I83-","I84-","T85-","D86-","T87-","Q88-","Q89-","T90-","R91-","L92-","G93-","S94-","S95-","H96-","T97-","Y98-","I99-","K100-","F101-","S102-","N103-","M104-","N105-","T106-","G107-","V108-","P109-","S110-","S111-","I112-","P113-","K114-","C115-","S116-","R117-","T118-","L119-","I121-","S122-","V123-","Y124-","C125-","D126-","Q127-","E128-","A129-","G130-","D131-","I132-","K133-","F134-","E135-","E136-","Y137-","T138-","Q139-","E140-","S141-","S142-","D143-","I144-","S145-","I146-","R147-","V148-","K149-","Y150-","D151-","S152-","S153-","C154-","I155-","D156-","Y157-","L158-","G159-","I160-","N161-","Q162-","S163-","F164-","M165-","N166-","E167-","C168-","I169-","R170-","R171-","I172-","T173-","T174-","W175-","D176-","R177-","E178-","S179-","C180-","V181-","R182-","I183-","D184-","T185-","Q186-","T187-","I188-","N189-","K190-","Y191-","L192-","K193-","S194-","C195-","T196-","N197-","T198-","K199-","F200-","D201-","R202-","N203-","V204-","Y205-","K206-","R207-","Y208-"],"OPG197":["D33-","D35N","E49-"],"OPG204":["E289K"],"OPG205":["H473R"],"OPG208":["T53I"],"OPG209":["G187R"],"OPG210":["S704Y"]},"labels":{"aa":"OPG023: D386N; OPG040: E37D, A168T; OPG045: E20D; OPG047: L166I, D229N; OPG049: P276S; OPG055: A118T; OPG074: S459F; OPG089: E178A; OPG102: H192Y; OPG105: S1083N; OPG108: A2V; OPG110: V80I, A135T; OPG113: A3T; OPG118: A281V, G381D; OPG120: A261V; OPG123: V29A; OPG125: H97N, L399I; OPG153: T343A, I370-, I371-, H408Y; OPG163: V46I; OPG172: D167V; OPG173: T30A; OPG174: C285Y; OPG185: T22I; OPG195: Y73-, D74-, Q75-, C76-, T77-, E78-, P79-, H80-, D81-, F82-, I83-, I84-, T85-, D86-, T87-, Q88-, Q89-, T90-, R91-, L92-, G93-, S94-, S95-, H96-, T97-, Y98-, I99-, K100-, F101-, S102-, N103-, M104-, N105-, T106-, G107-, V108-, P109-, S110-, S111-, I112-, P113-, K114-, C115-, S116-, R117-, T118-, L119-, I121-, S122-, V123-, Y124-, C125-, D126-, Q127-, E128-, A129-, G130-, D131-, I132-, K133-, F134-, E135-, E136-, Y137-, T138-, Q139-, E140-, S141-, S142-, D143-, I144-, S145-, I146-, R147-, V148-, K149-, Y150-, D151-, S152-, S153-, C154-, I155-, D156-, Y157-, L158-, G159-, I160-, N161-, Q162-, S163-, F164-, M165-, N166-, E167-, C168-, I169-, R170-, R171-, I172-, T173-, T174-, W175-, D176-, R177-, E178-, S179-, C180-, V181-, R182-, I183-, D184-, T185-, Q186-, T187-, I188-, N189-, K190-, Y191-, L192-, K193-, S194-, C195-, T196-, N197-, T198-, K199-, F200-, D201-, R202-, N203-, V204-, Y205-, K206-, R207-, Y208-; OPG197: D33-, D35N, E49-; OPG204: E289K; OPG205: H473R; OPG208: T53I; OPG209: G187R; OPG210: S704Y","clade":"clade IIa"}},"children":[{"name":"NODE_0000041","node_attrs":{"div":466,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["C334T","T602-","T603-","T604-","T605-","T606-","C3299A","T4722-","G4723-","A4724-","T4754-","G4755-","A4756-","C6423A","C6433T","C6436T","C6439T","-6448T","C6453A","-6475T","C6483A","C6505G","G6519T","-6521A","G6524T","T6580A","-6597T","A6601C","-6620G","-6625C","T6635A","T6641G","A6644G","-6647T","T6648A","G6650A","T6654A","C6661G","G6666T","T6667C","C6673A","T6675C","T6681C","-6687T","G6689A","-6698A","G6699A","A6702G","-6703T","-6704A","T6707G","A6709G","T6714A","T6715G","A6724G","T6725C","C6728G","-6747C","T6750A","T6754G","-6758G","A6764G","T6767G","G6771C","A6772T","C6777G","G6786A","T6792A","G6794A","G6797T","A6799T","G6800A","G6804A","-6810T","C6819T","T6822C","A6826G","T6829A","A6833C","T6834G","-6836G","T6838A","T6844C","G6853A","T6854G","-6855A","C6861G","A6865G","G6871C","-6874C","A6875T","T6881A","T6885C","A6894G","G6895A","A6899C","A6901T","A6911T","A6916T","A6918C","-6922T","A6923T","G6924-","A6930G","T6933G","T6946A","T6947A","T6952C","A6958G","-6959T","T6967G","T6969C","A6971T","T6972A","-6976G","-6977T","-6978T","G6983A","G6984T","-6987A","C6994T","C6995T","-7000C","T7003A","T7005G","A7009-","G7610A","T8335-","T10992C","C11237A","G12496T","G13465C","T16524C","G20501T","G22164A","C22169T","A23203G","A23289T","-25368A","A32972C","T33806C","T37110C","G40684T","T45966A","A45971-","T45972-","T45980-","T47499A","C50255T","G55330T","G64427A","C66773T","G71925A","C77775A","A78461C","A80583C","G83661A","A84278G","G88566T","C92630A","G103421A","C107921T","T108250C","C113843T","T125262C","G132531A","A133442G","C134489T","C135792T","-136558C","C136794T","G138298A","C141072T","G141294A","G144604A","T147634G","G150612-","A150613-","T150614-","A150615-","T150616-","G150617-","A150618-","T150619-","G150620-","G155105A","C155392T","T156215C","T156724-","G159963A","C160171T","G161470A","T162663G","A162722G","G163020T","C163836T","G165637T","T168345A","A168371-","C168372-","T168373-","G168374-","A168375-","T168376-","T168377-","G168378-","C168379-","A168380-","G168381-","T168382-","G168383-","T168384-","T168385-","C168386-","A168387-","T168388-","C168389-","G168390-","C168391-","C168392-","C168393-","A168394-","A168395-","C168396-","T168397-","G168398-","C168399-","A168400-","A168401-","G168402-","T168403-","G168404-","G168405-","A168406-","G168407-","G168408-","A168409-","T168410-","T168411-","G168412-","A168413-","T168414-","A168415-","A168416-","C168417-","T168418-","G168419-","A168420-","A168421-","G168422-","G168423-","C168424-","A168425-","A168426-","T168427-","G168428-","G168429-","A168430-","T168431-","T168432-","C168433-","A168434-","G168435-","A168436-","G168437-","T168438-","A168439-","G168440-","T168441-","T168442-","A168443-","T168444-","A168445-","T168448-","G168449-","A168450-","T168451-","C168452-","A168453-","A168454-","T168455-","G168456-","T168457-","A168458-","C168459-","A168460-","G168461-","A168462-","A168463-","C168464-","C168465-","C168466-","C168467-","A168468-","T168469-","G168470-","A168471-","C168472-","T168473-","T168474-","T168475-","A168476-","T168477-","T168478-","A168479-","T168480-","C168481-","A168482-","C168483-","C168484-","G168485-","A168486-","T168487-","A168488-","C168489-","T168490-","C168491-","A168492-","A168493-","C168494-","A168495-","A168496-","A168497-","C168498-","A168499-","C168500-","G168501-","T168502-","C168503-","T168504-","T168505-","G168506-","G168507-","A168508-","T168509-","C168510-","A168511-","T168512-","C168513-","T168514-","C168515-","A168516-","T168517-","A168518-","C168519-","A168520-","T168521-","A168522-","T168523-","A168524-","T168525-","T168526-","A168527-","A168528-","A168529-","T168530-","T168531-","C168532-","A168533-","G168534-","T168535-","A168536-","A168537-","C168538-","A168539-","T168540-","G168541-","A168542-","A168543-","T168544-","A168545-","C168546-","A168547-","G168548-","G168549-","T168550-","G168551-","T168552-","C168553-","C168554-","C168555-","A168556-","T168557-","C168558-","T168559-","A168560-","G168561-","T168562-","A168563-","T168564-","T168565-","C168566-","C168567-","A168568-","A168569-","A168570-","A168571-","T168572-","G168573-","T168574-","T168575-","C168576-","C168577-","A168578-","G168579-","A168580-","A168581-","C168582-","T168583-","C168584-","T168585-","C168586-","T168587-","T168589-","A168590-","T168591-","T168592-","T168593-","C168594-","T168595-","G168596-","T168597-","A168598-","T168599-","A168600-","T168601-","T168602-","G168603-","T168604-","G168605-","A168606-","T168607-","C168608-","A168609-","A168610-","G168611-","A168612-","G168613-","G168614-","C168615-","G168616-","G168617-","G168618-","A168619-","G168620-","A168621-","C168622-","A168623-","T168624-","A168625-","A168626-","A168627-","A168628-","T168629-","T168630-","T168631-","G168632-","A168633-","G168634-","G168635-","A168636-","G168637-","T168638-","A168639-","T168640-","A168641-","C168642-","T168643-","C168644-","A168645-","A168646-","G168647-","A168648-","A168649-","T168650-","C168651-","A168652-","A168653-","G168654-","T168655-","G168656-","A168657-","T168658-","A168659-","T168660-","C168661-","A168662-","G168663-","T168664-","A168665-","T168666-","T168667-","A168668-","G168669-","A168670-","G168671-","T168672-","T168673-","A168674-","A168675-","G168676-","T168677-","A168678-","T168679-","G168680-","A168681-","T168682-","T168683-","C168684-","A168685-","T168686-","C168687-","A168688-","T168689-","G168690-","T168691-","A168692-","T168693-","T168694-","G168695-","A168696-","T168697-","T168698-","A168699-","T168700-","C168701-","T168702-","G168703-","G168704-","G168705-","T168706-","A168707-","T168708-","T168709-","A168710-","A168711-","T168712-","C168713-","A168714-","A168715-","A168716-","G168717-","T168718-","T168719-","T168720-","C168721-","A168722-","T168723-","G168724-","A168725-","A168726-","T168727-","G168728-","A168729-","A168730-","T168731-","G168732-","T168733-","A168734-","T168735-","T168736-","C168737-","G168738-","A168739-","A168740-","G168741-","A168742-","A168743-","T168744-","T168745-","A168746-","C168747-","A168748-","A168749-","C168750-","A168751-","T168752-","G168753-","G168754-","G168755-","A168756-","T168757-","A168758-","G168759-","A168760-","G168761-","A168762-","A168763-","T168764-","C168765-","A168766-","T168767-","G168768-","C168769-","G168770-","T168771-","C168772-","A168773-","G168774-","A168775-","A168776-","T168777-","T168778-","G168779-","A168780-","T168781-","A168782-","C168783-","A168784-","C168785-","A168786-","G168787-","A168788-","C168789-","T168790-","A168791-","T168792-","A168793-","A168794-","A168795-","T168796-","A168797-","A168798-","A168799-","T168800-","A168801-","T168802-","C168803-","T168804-","T168805-","A168806-","A168807-","G168808-","T168809-","C168810-","T168811-","T168812-","G168813-","C168814-","A168815-","C168816-","C168817-","A168818-","A168819-","C168820-","A168821-","C168822-","A168823-","A168824-","A168825-","A168826-","T168827-","T168828-","C168829-","G168830-","A168831-","C168832-","C168833-","G168834-","T168835-","A168836-","A168837-","T168838-","G168839-","T168840-","C168841-","T168842-","A168843-","C168844-","A168845-","A168846-","A168847-","A168848-","G168849-","G168850-","T168851-","A168852-","C168945T","-169767T","T170754C","G172736A","C173569T","C174990T","C175537T","C178666T","-179072A","-179076T","C180258T","A180482-","T180483-","T180484-","A180485-","A180486-","A180487-","A180488-","A180489-","C181298T","T183552A","C187489T","G187888A","C188575T","C189627A","C192455-","A192456-","T192457-","C192487-","A192488-","T192489-","G193911T","A196610-","A196611-","A196612-","A196613-","A196614-","G196876A"],"OPG003":["D437Y"],"OPG003_dup":["D437Y"],"OPG019":["A11T"],"OPG023":["N135K","R555L","K637E"],"OPG025":["N601K"],"OPG037":["V89M"],"OPG039":["V277D"],"OPG052":["K64E"],"OPG074":["T599N"],"OPG083":["T97M"],"OPG085":["V587M"],"OPG099":["F37L"],"OPG100":["K152Q"],"OPG105":["V846I"],"OPG109":["D294E"],"OPG145":["M439T"],"OPG153":["A292T"],"OPG155":["T65I"],"OPG160":["M1I"],"OPG161":["A65T"],"OPG172":["S70A"],"OPG181":["A232T"],"OPG188":["N356K","Q376R"],"OPG195":["I39N","T48-","D49-","C50-","S51-","V52-","H53-","R54-","P55-","T56-","A57-","S58-","G59-","G60-","L61-","I62-","T63-","E64-","G65-","N66-","G67-","F68-","R69-","V70-","V71-","I72-"],"OPG197":["T32V"],"OPG204":["H336Y"],"OPG210":["L733I"]},"labels":{"aa":"OPG003: D437Y; OPG003_dup: D437Y; OPG019: A11T; OPG023: N135K, R555L, K637E; OPG025: N601K; OPG037: V89M; OPG039: V277D; OPG052: K64E; OPG074: T599N; OPG083: T97M; OPG085: V587M; OPG099: F37L; OPG100: K152Q; OPG105: V846I; OPG109: D294E; OPG145: M439T; OPG153: A292T; OPG155: T65I; OPG160: M1I; OPG161: A65T; OPG172: S70A; OPG181: A232T; OPG188: N356K, Q376R; OPG195: I39N, T48-, D49-, C50-, S51-, V52-, H53-, R54-, P55-, T56-, A57-, S58-, G59-, G60-, L61-, I62-, T63-, E64-, G65-, N66-, G67-, F68-, R69-, V70-, V71-, I72-; OPG197: T32V; OPG204: H336Y; OPG210: L733I"}},"children":[{"name":"MT903346","node_attrs":{"div":466,"accession":"MT903346","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"USA"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"strain":{"value":"MPXV-USA2003_099_Gambian_Rat"},"host":{"value":"Cricetomys gambianus"},"date":{"value":"2003-XX-XX"},"strain_display":{"value":"USA/MT903346/2003-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000042","node_attrs":{"div":467,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["-602T","C137626T","-196610A"]}},"children":[{"name":"MT903348","node_attrs":{"div":467,"accession":"MT903348","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"USA"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"strain":{"value":"MPXV-USA2003_099_Rope_Squirrel"},"host":{"value":"Funisciurus"},"date":{"value":"2003-XX-XX"},"strain_display":{"value":"USA/MT903348/2003-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"DQ011153","node_attrs":{"div":467,"accession":"DQ011153","author":{"author":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S.","value":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S."},"country":{"value":"USA"},"institution":{"value":"National Center for Infectious Diseases, Centers for Disease Control and Prevention (US CDC), USA"},"strain":{"value":"DQ011153"},"host":{"value":"Cynomys"},"date":{"value":"2003-XX-XX"},"strain_display":{"value":"USA/DQ011153/2003-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C49T"]}}},{"name":"MT903347","node_attrs":{"div":467,"accession":"MT903347","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"USA"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"strain":{"value":"MPXV-USA2003_099_Dormouse"},"host":{"value":"Gliridae"},"date":{"value":"2003-XX-XX"},"strain_display":{"value":"USA/MT903347/2003-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"DQ011157","node_attrs":{"div":467,"accession":"DQ011157","author":{"author":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S.","value":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S."},"country":{"value":"USA"},"institution":{"value":"National Center for Infectious Diseases, Centers for Disease Control and Prevention (US CDC), USA"},"strain":{"value":"DQ011157"},"host":{"value":"Homo sapiens"},"date":{"value":"2003-XX-XX"},"strain_display":{"value":"USA/DQ011157/2003-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000045","node_attrs":{"div":408,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["G707A","C2959T","G3843A","C5441A","T6581C","C6593-","-6597C","T6609G","A6651C","T6669G","A6679-","T6688C","-6698G","G6705-","T6706-","A6719C","T6737C","A6745-","G6746-","A6748-","T6749-","-6758A","T6761C","T6762C","A6768G","G6788-","T6802G","A6817C","-6836A","A6837G","T6869C","A6890C","A6913G","-6922C","T6939C","A6950C","A6951G","A6953C","T6957G","-6977A","-6978A","A6986-","G7186A","C13709T","T19165A","T28278C","T38382A","G47813T","G85661A","A85968G","A88560T","T97911C","C115877T","A136556-","T136557-","A136559-","T136560-","A136561-","T136562-","C136563-","T136570-","A161541-","-168588C","T170904-","G174537-","A174538-","T174539-","G174540-","A174541-","A174542-","T180475-","T180476-","A180477-","A180478-","A180479-","A180480-","A180481-","G191769T","C193367T","G194251A","C196503T"],"OPG003":["S550N"],"OPG003_dup":["S550N"],"OPG015":["W239L"],"OPG015_dup":["W239L"],"OPG025":["C520Y"],"OPG056":["D218V"],"OPG107":["K153E"],"OPG134":["A43V"],"OPG153":["E366-","D372-"]},"labels":{"aa":"OPG003: S550N; OPG003_dup: S550N; OPG015: W239L; OPG015_dup: W239L; OPG025: C520Y; OPG056: D218V; OPG107: K153E; OPG134: A43V; OPG153: E366-, D372-"}},"children":[{"name":"NODE_0000046","node_attrs":{"div":435,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["A2760-","A2761-","G3051A","A4691G","-4693C","-4694T","-4695T","C5809T","C6423A","C6433T","C6436T","C6439T","-6448T","C6453A","-6475T","C6483A","C6505G","G6519T","-6521A","G6524T","A6578T","T6579A","T6583A","T6586A","T6587A","G6591T","G6602C","G6608A","G6619A","-6620T","-6625T","T6638A","A6643T","-6647A","T6660A","-6687A","G6700A","G6713C","G6752T","T6763A","C6769A","C6775A","C6779T","C6784T","C6785A","G6791T","C6807A","-6810A","A6815T","G6828C","A6830T","G6843C","T6846A","-6855T","G6863A","C6870T","-6874G","T6877A","G6878C","G6880T","C6883A","G6887A","G6896T","T6934A","T6935A","A6938T","A6943T","-6959G","T6966A","-6976T","C6993T","C6999G","-7000T","A7004T","C7008T","T13272-","A13273-","A15512-","C15513-","G15514-","T15515-","C15516-","A15517-","A15518-","T15519-","G15520-","G15521-","T15522-","A15523-","C15524-","A15525-","A15526-","A15527-","T15528-","T15529-","T15530-","T15531-","A15532-","C19281T","G19891A","T20697C","T24732C","-25368A","G36310T","T38583C","T48389G","T62580A","C71655G","C79980T","T80764G","C87501T","C93701T","A95738G","C125798T","C133086T","T133087C","-133090T","G133115-","C145219A","A156894C","A164460T","C164835T","-169763A","-169764C","-169765A","-169767A","A169772G","-172087T","G178332T","-179072A","-179076T","T180075A","T180218C","A183473G","G191401A","-192515A","-192516A","-192517G","T192519C","C194159T","T194449-","T194450-"],"OPG034":["R39C"],"OPG036":["D123G"],"OPG044":["V63A"],"OPG056":["N151S"],"OPG091":["L96V"],"OPG102":["T299I"],"OPG104":["N86H"],"OPG147":["V64M"],"OPG197":["-33D","N35D"],"OPG208":["N270K","F318S"]},"labels":{"aa":"OPG034: R39C; OPG036: D123G; OPG044: V63A; OPG056: N151S; OPG091: L96V; OPG102: T299I; OPG104: N86H; OPG147: V64M; OPG197: -33D, N35D; OPG208: N270K, F318S"}},"children":[{"name":"KJ642616","node_attrs":{"div":454,"accession":"KJ642616","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"France"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"KJ642616"},"date":{"value":"1968-XX-XX"},"strain_display":{"value":"France/KJ642616/1968-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T580G","T19608C","T23228A","T24498A","G27605A","C29763T","C37493T","T56538G","A87055G","C102787T","C112599A","G119877A","G121660T","C125897T","G133059A","G133454A","-136561A","-136562T","-136563C","-136570A","T146884-","T146885-","T146886-","A146887-","T146888-","A146889-","T146890-","G150612-","A150613-","T150614-","A150615-","T150616-","G150617-","A150618-","T150619-","G150620-","C156438A","A157609C","C158379T","A160363-","G160364-","G163255A","G168753T","A196630C"],"OPG034":["Y133C"],"OPG040":["Q327H"],"OPG047":["D478N"],"OPG074":["K196N"],"OPG108":["V2A"],"OPG147":["A31T"],"OPG153":["-366D","-372D"]},"labels":{"aa":"OPG034: Y133C; OPG040: Q327H; OPG047: D478N; OPG074: K196N; OPG108: V2A; OPG147: A31T; OPG153: -366D, -372D"}}},{"name":"NODE_0000047","node_attrs":{"div":438,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["-607T","C7611A","C65892T","G116640A","C133521-","A136543-","T136544-","C136545-","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","T136571-","C136572-","G148317-","-196615A"],"OPG019":["A11D"],"OPG084":["P391S"],"OPG135":["S91L"],"OPG153":["D367-","D368-","D369-","D373-","D374-","D375-"]},"labels":{"aa":"OPG019: A11D; OPG084: P391S; OPG135: S91L; OPG153: D367-, D368-, D369-, D373-, D374-, D375-"}},"children":[{"name":"AY753185","node_attrs":{"div":442,"accession":"AY753185","author":{"author":"Chen,N.,Li,G.,Liszewski,M.K.,Atkinson,J.P.,Jahrling,P.B.,Feng,Z.,Schriewer,J.,Buck,C.,Wang,C.,Lefkowitz,E.J.,Esposito,J.J.,Harms,T.,Damon,I.K.,Roper,R.L.,Upton,C.,Buller,R.M.,Buller,R.M.L.","value":"Chen,N.,Li,G.,Liszewski,M.K.,Atkinson,J.P.,Jahrling,P.B.,Feng,Z.,Schriewer,J.,Buck,C.,Wang,C.,Lefkowitz,E.J.,Esposito,J.J.,Harms,T.,Damon,I.K.,Roper,R.L.,Upton,C.,Buller,R.M.,Buller,R.M.L."},"institution":{"value":"Biochemistry & Microbiology, University of Victoria, Canada"},"strain":{"value":"AY753185"},"date":{"value":"1958-XX-XX"},"strain_display":{"value":"nan/AY753185/1958-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G32868A","G50614A","C137466T","C170999T","A181253-"],"OPG049":["S95L"],"OPG070":["D9N"],"OPG153":["E68K"]},"labels":{"aa":"OPG049: S95L; OPG070: D9N; OPG153: E68K"}}},{"name":"AY603973","node_attrs":{"div":441,"accession":"AY603973","author":{"author":"Chen,N.,Li,G.,Liszewski,M.K.,Atkinson,J.P.,Jahrling,P.B.,Feng,Z.,Schriewer,J.,Buck,C.,Wang,C.,Lefkowitz,E.J.,Esposito,J.J.,Harms,T.,Damon,I.K.,Roper,R.L.,Upton,C.,Buller,R.M.,Buller,R.M.L.","value":"Chen,N.,Li,G.,Liszewski,M.K.,Atkinson,J.P.,Jahrling,P.B.,Feng,Z.,Schriewer,J.,Buck,C.,Wang,C.,Lefkowitz,E.J.,Esposito,J.J.,Harms,T.,Damon,I.K.,Roper,R.L.,Upton,C.,Buller,R.M.,Buller,R.M.L."},"institution":{"value":"Biochemistry & Microbiology, University of Victoria, Canada"},"strain":{"value":"AY603973"},"date":{"value":"1961-XX-XX"},"strain_display":{"value":"nan/AY603973/1961-XX-XX"},"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["G775A","G90845A","G92261A","A124807G","-146877A","-146878T","-146879T","-146880T","-146881T","-146882A","-146883T","A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","C196435T"],"OPG111":["S194N"]},"labels":{"aa":"OPG111: S194N"}}}]}]},{"name":"NODE_0000048","node_attrs":{"div":419,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["T4087G","A4864G","C6431T","G6432T","-6448A","A6451T","A6460-","-6475A","C6476G","C6478A","G6481A","T6485A","G6486A","C6489A","G6494T","C6498T","A6500T","C6501T","C6507T","A6515C","-6521T","A6528C","C6529A","T6534A","T6535A","G6538A","T6543C","G7927A","G10999A","T25369-","C25370-","C28393T","C43244T","T69852C","C133520T","G135371A","A150549T","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-150603G","-150604A","-150605T","-150606A","-150607T","-150608G","-150609A","-150610T","-150611G","T154017C","A163207-","A163208-","C163209-","T163210-","A163211-","A163212-","C163213-","T163214-","-169767T","T179068-","T179069-","A179070-","T179071-","T179073-","A179074-","T179075-","A179077-","T179078-","C190338T","T192346C","A193123C"],"OPG003":["E174A"],"OPG003_dup":["E174A"],"OPG040":["D37-"],"OPG063":["V149I"]},"labels":{"aa":"OPG003: E174A; OPG003_dup: E174A; OPG040: D37-; OPG063: V149I"}},"children":[{"name":"AY741551","node_attrs":{"div":453,"accession":"AY741551","author":{"author":"Chen,N.,Li,G.,Liszewski,M.K.,Atkinson,J.P.,Jahrling,P.B.,Feng,Z.,Schriewer,J.,Buck,C.,Wang,C.,Lefkowitz,E.J.,Esposito,J.J.,Harms,T.,Damon,I.K.,Roper,R.L.,Upton,C.,Buller,R.M.,Buller,R.M.L.","value":"Chen,N.,Li,G.,Liszewski,M.K.,Atkinson,J.P.,Jahrling,P.B.,Feng,Z.,Schriewer,J.,Buck,C.,Wang,C.,Lefkowitz,E.J.,Esposito,J.J.,Harms,T.,Damon,I.K.,Roper,R.L.,Upton,C.,Buller,R.M.,Buller,R.M.L."},"country":{"value":"Sierra Leone"},"institution":{"value":"Biochemistry & Microbiology, University of Victoria, Canada"},"strain":{"value":"Sierra Leone"},"date":{"value":"1970-XX-XX"},"strain_display":{"value":"Sierra Leone/AY741551/1970-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G2387A","G3432A","A4696-","A4697-","C4698-","T4699-","A4700-","A4701-","C4702-","T4703-","T4704-","A4705-","T4706-","G4707-","A4708-","C4709-","T4710-","T4711-","A4712-","A4713-","C4714-","T4715-","A4716-","A4717-","C4718-","T4719-","T4720-","A4721-","T4722-","G4723-","A4724-","C4725-","T4726-","T4727-","A4728-","A4729-","C4730-","T4731-","A4732-","A4733-","C4734-","T4735-","T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","A4748-","A4749-","C4750-","T4751-","T4752-","A4753-","T4754-","G4755-","A4756-","C4757-","T4758-","T4759-","A4760-","A4761-","C4762-","T4763-","A4764-","A4765-","C4766-","T4767-","T4768-","A4769-","T4770-","G4771-","A4772-","C4773-","T4774-","T4775-","G5777T","T6580A","C6581T","-6593C","C6597T","A6601C","G6609T","-6620G","-6625C","T6635A","T6641G","A6644G","-6647T","T6648A","G6650A","C6651A","T6654A","C6661G","G6666T","T6667C","G6669T","C6673A","T6675C","-6679A","T6681C","-6687T","C6688T","G6689A","G6698A","G6699A","A6702G","-6703T","-6704A","-6705G","-6706T","T6707G","A6709G","T6714A","T6715G","C6719A","A6724G","T6725C","C6728G","C6737T","-6745A","-6746G","-6747C","-6748A","-6749T","T6750A","T6754G","A6758G","C6761T","C6762T","A6764G","T6767G","G6768A","G6771C","A6772T","C6777G","G6786A","-6788G","T6792A","G6794A","G6797T","A6799T","G6800A","G6802T","G6804A","-6810T","C6817A","C6819T","T6822C","A6826G","T6829A","A6833C","T6834G","A6836G","G6837A","T6838A","T6844C","G6853A","T6854G","-6855A","C6861G","A6865G","C6869T","G6871C","-6874C","A6875T","T6881A","T6885C","C6890A","A6894G","G6895A","A6899C","A6901T","A6911T","G6913A","A6916T","A6918C","C6922T","A6923T","G6924-","A6930G","T6936C","C6939T","T6945G","C6950A","G6951A","C6953T","C6955T","G6957T","A6958T","-6959T","A6964C","A6965T","-6976A","A6977G","C6979G","T6981A","G6983A","-6986A","-6987G","T6989C","A6992G","C6994A","C6995G","-7000A","C7002A","T7003G","T7007A","C7010G","T7014A","C7016A","C7022G","T7024G","C7026A","A7033G","C7037G","C7041A","C7046T","C7050A","G7052A","A7053C","T7058A","G7059A","C7062G","G7063T","T7065G","C7068A","A7069G","C18480T","A21930G","C28278T","G28324A","C29640T","G79597A","C79729A","G84125A","C84980T","C89970T","G94626A","C94743T","G95525A","C110255T","G118298T","C123888A","G133545A","G134297T","C134622T","G134915A","-136570T","A152605T","C154167A","C154410T","A160211-","A160212-","C161917T","C163183-","T163184-","C163185-","T163186-","T163187-","T163188-","T163189-","T163190-","A163191-","A163192-","C163193-","T163194-","A163195-","A163196-","C163197-","T163198-","A163199-","A163200-","C163201-","T163202-","A163203-","A163204-","C163205-","T163206-","C163215-","T163216-","T163217-","A163218-","T163219-","G165759A","G172195A","C175461A","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","G180374A","A185597G","C188478T","C188879T","A189894G","C191433A","A192435-","A192436-","G192437-","T192438-","C192439-","A192440-","T192441-","A192442-","A192443-","G192444-","T192445-","T192446-","A192447-","G192448-","T192449-","T192450-","A192451-","A192452-","G192453-","T192454-","C192455-","A192456-","T192457-","A192458-","A192459-","G192460-","T192461-","T192462-","A192463-","G192464-","T192465-","T192466-","A192467-","A192468-","G192469-","T192470-","C192471-","A192472-","T192473-","A192474-","A192475-","G192476-","T192477-","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-","A192490-","A192491-","G192492-","T192493-","T192494-","A192495-","G192496-","T192497-","T192498-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","C193778T","C194823T","-196615A","-196616A","-196617A"],"OPG002":["S122L"],"OPG002_dup":["S122L"],"OPG015":["A127E"],"OPG015_dup":["A127E"],"OPG031":["D117N"],"OPG153":["-366E"],"OPG190":["S213N"],"OPG197":["T32V"],"OPG200":["G16R"]},"labels":{"aa":"OPG002: S122L; OPG002_dup: S122L; OPG015: A127E; OPG015_dup: A127E; OPG031: D117N; OPG153: -366E; OPG190: S213N; OPG197: T32V; OPG200: G16R"}}},{"name":"NODE_0000049","node_attrs":{"div":448,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["T600-","T601-","T602-","T603-","T604-","T605-","T606-","A6578T","T6579A","T6583A","T6586A","T6587A","G6591T","G6602C","G6608A","G6619A","-6620T","-6625T","T6638A","A6643T","-6647A","T6660A","-6687A","G6700A","G6713C","G6752T","T6763A","C6769A","C6775A","C6779T","C6784T","C6785A","G6791T","C6807A","-6810A","A6815T","G6828C","A6830T","G6843C","T6846A","-6855T","G6863A","C6870T","-6874G","T6877A","G6878C","G6880T","C6883A","G6887A","G6896T","T6934A","T6935A","A6938T","A6943T","-6959G","T6966A","-6976T","C6993T","C6999G","-7000T","A7004T","C7008T","G8774A","A8794G","G9698A","C15082T","C20362T","C33964T","C38427T","C45637T","C50494A","C50572T","C55215A","G72890T","A81454C","G93357A","G121527T","G125116A","C128093T","T132868C","G133163A","G133255A","G133428-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","T136571-","C136572-","A142508G","C150444A","-150569A","-150570T","-150571A","-150572T","-150573G","-150574A","-150575T","-150576G","-150577G","-150578A","-150579T","-150580A","-150581T","-150582G","-150583A","-150584T","-150585G","G151505T","C154806T","T156450A","G156637T","C160271G","A169757-","C169758-","A169759-","G169760-","A169761-","T169762-","C188457T","T189549C","A189726-","T189727-","T189728-","A196608-","A196609-","A196610-","A196611-","A196612-","A196613-","A196614-"],"OPG021":["V38I"],"OPG035":["G15S"],"OPG044":["V63A"],"OPG052":["R11Q"],"OPG056":["C203Y"],"OPG064":["A88T"],"OPG092":["Q20K"],"OPG105":["E110A"],"OPG113":["A543T"],"OPG140":["H74N"],"OPG153":["D367-","D368-","D369-"],"OPG163":["I103V"],"OPG181":["A132V"],"OPG197":["T30V","D31-","T32-"]},"labels":{"aa":"OPG021: V38I; OPG035: G15S; OPG044: V63A; OPG052: R11Q; OPG056: C203Y; OPG064: A88T; OPG092: Q20K; OPG105: E110A; OPG113: A543T; OPG140: H74N; OPG153: D367-, D368-, D369-; OPG163: I103V; OPG181: A132V; OPG197: T30V, D31-, T32-"}},"children":[{"name":"KP849470","node_attrs":{"div":464,"accession":"KP849470","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Yoshinori,N.,Muyembe,J.-J.,Kingbeni,P.M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Yoshinori,N.,Muyembe,J.-J.,Kingbeni,P.M."},"country":{"value":"Côte d'Ivoire"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"Cote d'Ivoire_1971"},"date":{"value":"1971-XX-XX"},"strain_display":{"value":"Côte d'Ivoire/KP849470/1971-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A9454-","C15863-","C15864-","T15865-","T50665-","C52231T","C65466T","T72702C","C72750T","A86790G","G105195A","A111561G","G116852A","A121165C","T134625G","T136553-","C136554-","G136573-","C141287T","C151475A","C162897T","-163207A","-163208A","-163209C","-163210T","-163211A","-163212A","-163213C","-163214T","T163407C","C167177T","A169751-","C169752-","A169753-","G169754-","A169755-","T169756-","A171862C"],"OPG070":["F26-"],"OPG092":["M66I"],"OPG197":["T28V","D29-","V30-"],"OPG199":["E292A"]},"labels":{"aa":"OPG070: F26-; OPG092: M66I; OPG197: T28V, D29-, V30-; OPG199: E292A"}}},{"name":"NODE_0000050","node_attrs":{"div":450,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["C7A","A14T","G19A","G21A","C23T","T38A","T51A","G54A","C60T","G66A","T68A","A79C","T88A","G8143T","A28532-","G156023A","A197122C","T197131G","A197142T","C197144T","G197150A","C197156T","A197159T","A197172T","T197182A","A197186C","T197192A","T197196A","G197203T"],"OPG044":["M148-"],"OPG153":["-372D"]},"labels":{"aa":"OPG044: M148-; OPG153: -372D"}},"children":[{"name":"DQ011156","node_attrs":{"div":452,"accession":"DQ011156","author":{"author":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S.","value":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S."},"country":{"value":"Liberia"},"institution":{"value":"National Center for Infectious Diseases, Centers for Disease Control and Prevention (US CDC), USA"},"strain":{"value":"DQ011156"},"host":{"value":"Homo sapiens"},"date":{"value":"1970-XX-XX"},"strain_display":{"value":"Liberia/DQ011156/1970-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C39509T","G42709T","-179068T","-179069T","-179070A","-179071T","-179072A","-179073T","-179074A","-179075T","-179076T","-179077A","-179078T"],"OPG063":["T327K"]},"labels":{"aa":"OPG063: T327K"}}},{"name":"NODE_0000051","node_attrs":{"div":463,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["-600T","-601T","-602T","A2840C","A6577G","T6578A","A6579T","C6581A","A6583T","A6586T","A6587T","T6588A","A6590C","T6591G","-6593T","T6594A","C6597T","C6602G","G6607C","A6608G","G6609T","A6619G","T6620G","T6625C","T6635A","A6638T","T6641G","T6643A","A6644G","A6647T","T6648A","G6650A","C6651A","T6654A","A6660T","C6661G","G6666T","T6667C","G6669T","C6673A","T6675C","-6679A","T6681C","A6687T","C6688T","G6689A","G6698A","G6699A","A6700G","A6702G","-6703T","-6704A","-6705G","-6706T","T6707G","A6709G","C6713G","T6714A","T6715G","C6719A","A6724G","T6725C","C6728G","C6737T","-6745A","-6746G","-6747C","-6748A","-6749T","T6750A","T6752G","T6754G","A6758G","C6761T","C6762T","A6763T","A6764G","T6767G","G6768A","A6769C","G6771C","A6772T","A6775C","C6777G","T6779C","T6784C","A6785C","G6786A","-6788G","T6791G","T6792A","G6794A","G6797T","A6799T","G6800A","G6802T","G6804A","A6807C","A6810T","T6815A","C6817A","C6819T","T6822C","A6826G","C6828G","T6829A","T6830A","A6833C","T6834G","A6836G","G6837A","T6838A","C6843G","T6844C","A6846T","G6853A","T6854G","T6855A","C6861G","A6863G","A6865G","C6869T","T6870C","G6871C","G6874C","A6875T","A6877T","C6878G","T6880G","T6881A","A6883C","T6885C","A6887G","C6890A","A6894G","G6895A","T6896G","A6899C","A6901T","A6911T","G6913A","A6916T","A6918C","C6922T","A6923T","G6924-","A6930G","A6934T","A6935T","T6936C","T6938A","C6939T","T6943A","T6945G","C6950A","G6951A","C6953T","C6955T","G6957T","A6958T","G6959T","A6964C","A6965T","A6966T","A6978C","C6979G","G6983A","-6986A","-6987G","T6989C","A6992G","T6993C","C6994A","C6995G","G6999C","T7000A","C7002A","T7003G","T7004A","T7007A","T7008C","C7010G","T7014A","C7016A","C7022G","T7024G","C7026A","A7033G","C7037G","C7041A","C7046T","C7050A","G7052A","A7053C","T7058A","G7059A","C7062G","G7063T","T7065G","C7068A","A7069G","G10039A","C12561T","A15700-","G15701-","G46380A","A69837G","C89937A","C101011A","A116643G","G140316A","C159500A","T172828A","G187503T","G188419T","A190071-","T190072-","T194370G","-196608A","-196609A","-196610A"],"OPG023":["V114I"],"OPG065":["A35V"],"OPG135":["V90A"],"OPG185":["A195E"]},"labels":{"aa":"OPG023: V114I; OPG065: A35V; OPG135: V90A; OPG185: A195E"}},"children":[{"name":"KJ136820","node_attrs":{"div":467,"accession":"KJ136820","author":{"author":"Radonic,A.,Metzger,S.,Dabrowski,P.W.,Couacy-Hymann,E.,Schuenadel,L.,Kurth,A.,Matz-Rensing,K.,Boesch,C.,Leendertz,F.H.,Nitsche,A.","value":"Radonic,A.,Metzger,S.,Dabrowski,P.W.,Couacy-Hymann,E.,Schuenadel,L.,Kurth,A.,Matz-Rensing,K.,Boesch,C.,Leendertz,F.H.,Nitsche,A."},"country":{"value":"Côte d'Ivoire"},"institution":{"value":"Centre for Biological Security, Robert Koch Institute, Germany"},"strain":{"value":"KJ136820"},"host":{"value":"Platyrrhini"},"date":{"value":"2012-03-XX"},"strain_display":{"value":"Côte d'Ivoire/KJ136820/2012-03-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C4538T","T16298C","G35634A","A167909C","-179068T","-179069T","-179070A","-179071T","-179072A","-179073T","-179074A","-179075T","-179076T","-179077A","-179078T","G192672A"],"OPG003":["D24N"],"OPG003_dup":["D24N"],"OPG027":["N27S"]},"labels":{"aa":"OPG003: D24N; OPG003_dup: D24N; OPG027: N27S"}}},{"name":"NODE_0000052","node_attrs":{"div":467,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["T4722-","G4723-","A4724-","C4725-","T4726-","T4727-","A4728-","A4729-","C4730-","T4731-","A4732-","A4733-","G4739A","C4741-","T4742-","T4743-","G21441A","A27251G","-28532A","-136559A","-136560T","-136561A","-136562T","-136563C","-136564A","-136565T","-136566C","-136567A","-136568T","-136569C","-136570A","-136571T","-136572C","-146877A","-146878T","-146879T","-146880T","-146881T","-146882A","-146883T","A150569-","T150570-","A150571-","T150572-","G150573-","A150574-","T150575-","G150576-","G150577-","A150578-","T150579-","A150580-","T150581-","G150582-","A150583-","T150584-","G150585-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-169757A","-169758C","-169759A","-169760G","-169761A","-169762T","-169763A","-169764C","-169765A","T169767A","A169772G","T179120-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","C186017T","A192467-","A192468-","G192469-","C192471T","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-"],"OPG044":["-148M"],"OPG153":["-366D","-367D","-368D","-369D"],"OPG197":["V30T","-31D","-32T","-33D","N35D"]},"labels":{"aa":"OPG044: -148M; OPG153: -366D, -367D, -368D, -369D; OPG197: V30T, -31D, -32T, -33D, N35D"}},"children":[{"name":"NODE_0000053","node_attrs":{"div":473,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["-603T","-604T","A4744-","A4745-","C4746-","T4747-","A4748-","A4749-","C4750-","T4751-","T4752-","A4753-","T4754-","G4755-","A4756-","C4757-","T4758-","T4759-","G57148A","C137932T","T145515-","C152375A","G155747T","G158403A","G177534T","T179183-","T179184-","A179185-","T179186-","-196611A","-196612A"],"OPG154":["G40E"],"OPG205":["D627Y"]},"labels":{"aa":"OPG154: G40E; OPG205: D627Y"}},"children":[{"name":"MN346702","node_attrs":{"div":473,"accession":"MN346702","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"Côte d'Ivoire"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"strain":{"value":"MPXV_TNP_2018_East_Paddy"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2018-05-11"},"strain_display":{"value":"Côte d'Ivoire/MN346702/2018-05-11"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179121-"]}}},{"name":"MN346703","node_attrs":{"div":473,"accession":"MN346703","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"Côte d'Ivoire"},"institution":{"value":"Robert Koch Institute, Project Group Epidemiology of Highly Pathogenic Microorganisms"},"strain":{"value":"MPXV_TNP_2018_East_Placali"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2018-05-20"},"strain_display":{"value":"Côte d'Ivoire/MN346703/2018-05-20"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-605T","-136556A","-136557T","-136558C","-179068A","-179069T","-179070A","-179071C","-179074A","-179075T","-179076T","-179077A","-179078T","-179120T","-179122A","-179123T","-179124A","-179125T","-179126A","-196613A"]}}}]},{"name":"NODE_0000054","node_attrs":{"div":472,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["A22266-","T22267-","G22268-","A22269-","A22270-","G22271-","A22272-","A22273-","G22274-","T22275-","T22276-","C22277-","T22278-","T22279-","C22280-","T22281-","C44980T","C131652T","C133187-","A133188-","T133189-","T133190-","T133191-","C133192-","A133193-","T133194-","C133195-","C133196-","C133197-","C133198-","A133199-","T133200-","G133201-","C133202-","T133204A","T133749C","-136556A","-136557T","-136558C","C153524A","G156651T"],"OPG037":["E52-","E53-","L54-","L55-","H56-"],"OPG064":["D307N"],"OPG151":["T910I"],"OPG180":["T278K"]},"labels":{"aa":"OPG037: E52-, E53-, L54-, L55-, H56-; OPG064: D307N; OPG151: T910I; OPG180: T278K"}},"children":[{"name":"MN346700","node_attrs":{"div":472,"accession":"MN346700","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"Côte d'Ivoire"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"strain":{"value":"MPXV_TNP_2017_South_Ravel_2"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-01-31"},"strain_display":{"value":"Côte d'Ivoire/MN346700/2017-01-31"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-22266A","-22267T","-22268G","-22269A","-22270A","-22271G","-22272A","-22273A","-22274G","-22275T","-22276T","-22277C","-22278T","-22279T","-22280C","-22281T","A136556-","T136557-","C136558-","T150549-","G150550-","G150551-","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","T150567-","G150568-","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179121-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-"],"OPG037":["-52E","-53E","-54L","-55L","-56H"]},"labels":{"aa":"OPG037: -52E, -53E, -54L, -55L, -56H"}}},{"name":"MN346699","node_attrs":{"div":472,"accession":"MN346699","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"Côte d'Ivoire"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"strain":{"value":"MPXV_TNP_2017_South_Ravel_1"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-01-23"},"strain_display":{"value":"Côte d'Ivoire/MN346699/2017-01-23"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-22266A","-22267T","-22268G","-22269A","-22270A","-22271G","-22272A","-22273A","-22274G","-22275T","-22276T","-22277C","-22278T","-22279T","-22280C","-22281T","A136556-","T136557-","C136558-","T150549-","G150550-","G150551-","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","T150567-","G150568-","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179121-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-"],"OPG037":["-52E","-53E","-54L","-55L","-56H"]},"labels":{"aa":"OPG037: -52E, -53E, -54L, -55L, -56H"}}},{"name":"MN346701","node_attrs":{"div":472,"accession":"MN346701","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"Côte d'Ivoire"},"institution":{"value":"Robert Koch Institute, Project Group Epidemiology of Highly Pathogenic Microorganisms"},"strain":{"value":"MPXV_TNP_2017_South_Woodstock"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-01-14"},"strain_display":{"value":"Côte d'Ivoire/MN346701/2017-01-14"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-603T","-604T","-605T","G610-","T611-","A6786G","G6788T","A6789C","G6791T","A6792T","A6793G","A6794G","A6796G","T6797G","T6799A","A6800G","A6801T","C6807A","T6810G","G6811A","G6814T","A6815C","T6819C","T6821A","C6822T","C6823A","T6922A","T6923A","-6924G","T6926G","T6933C","C6936G","C6940A","A6941T","G6945T","T6946A","T6947A","T6952C","T6953A","T6955C","T6958G","C6964A","T6965A","T6967G","T6969C","A6971T","T6972A","T6976G","A6977T","C6978T","G6979C","G6984T","G6987A","C6989T","G6992A","A6994T","G6995T","A7000C","A7002C","T7005G","A7007T","A7009-","G7010C","A7014T","A7016C","G7022C","G7024T","A7026C","G7033A","G7037C","A7041C","T7046C","A7050C","A7052G","C7053A","A7058T","A7059G","G7062C","T7063G","G7065T","A7068C","G7069A","-22266A","-22267T","-22268G","-22269A","-22270A","-22271G","-22272A","-22273A","-22274G","-22275T","-22276T","-22277C","-22278T","-22279T","-22280C","-22281T","A136556-","T136557-","C136558-","A136559-","T136560-","T150549-","G150550-","G150551-","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","T150567-","G150568-","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196611A"],"OPG037":["-52E","-53E","-54L","-55L","-56H"]},"labels":{"aa":"OPG037: -52E, -53E, -54L, -55L, -56H"}}},{"name":"MN346698","node_attrs":{"div":472,"accession":"MN346698","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"Côte d'Ivoire"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"strain":{"value":"MPXV_TNP_2017_South_Pushkin"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-01-24"},"strain_display":{"value":"Côte d'Ivoire/MN346698/2017-01-24"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-22266A","-22267T","-22268G","-22269A","-22270A","-22271G","-22272A","-22273A","-22274G","-22275T","-22276T","-22277C","-22278T","-22279T","-22280C","-22281T","A136556-","T136557-","C136558-","T150549-","G150550-","G150551-","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","T150567-","G150568-","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179121-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-"],"OPG037":["-52E","-53E","-54L","-55L","-56H"]},"labels":{"aa":"OPG037: -52E, -53E, -54L, -55L, -56H"}}},{"name":"MN346697","node_attrs":{"div":472,"accession":"MN346697","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"Côte d'Ivoire"},"institution":{"value":"Robert Koch Institute, Project Group Epidemiology of Highly Pathogenic Microorganisms"},"strain":{"value":"MPXV_TNP_2017_North_Surprise_2"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-04-14"},"strain_display":{"value":"Côte d'Ivoire/MN346697/2017-04-14"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A15924-","T15925-","T15926-","A15927-","A15928-","T15929-","C15930-","C15931-","A15932-","T15933-","G15934-","G15935-","A15936-","C15937-","T15938-","C15939-","A15940-","T15941-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-"]}}},{"name":"MN346696","node_attrs":{"div":472,"accession":"MN346696","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"Côte d'Ivoire"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"strain":{"value":"MPXV_TNP_2017_North_Surprise_1"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-04-03"},"strain_display":{"value":"Côte d'Ivoire/MN346696/2017-04-03"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-179120T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A"]}}},{"name":"MN346695","node_attrs":{"div":472,"accession":"MN346695","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"Côte d'Ivoire"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"strain":{"value":"MPXV_TNP_2017_North_Sidonie"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-04-02"},"strain_display":{"value":"Côte d'Ivoire/MN346695/2017-04-02"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T179183-"]}}},{"name":"MN346692","node_attrs":{"div":472,"accession":"MN346692","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"Côte d'Ivoire"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"strain":{"value":"MPXV_TNP_2017_North_Mama"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-03-05"},"strain_display":{"value":"Côte d'Ivoire/MN346692/2017-03-05"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-179120T","-179122A","-179123T","-179124A","-179125T","-179126A","-179127C","-179128A","-179129T","-179130T","-179131A","-179132T","-179133A","-179134T","-179135A","-179136C","-179137A","-179138T","-179139T","-179140A","-179141T","-179142A","-179143T","-179144A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A"]}}},{"name":"MN346694","node_attrs":{"div":472,"accession":"MN346694","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"Côte d'Ivoire"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"strain":{"value":"MPXV_TNP_2017_North_Saro"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-03-28"},"strain_display":{"value":"Côte d'Ivoire/MN346694/2017-03-28"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-179120T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A"]}}},{"name":"MN346690","node_attrs":{"div":472,"accession":"MN346690","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"Côte d'Ivoire"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"strain":{"value":"MPXV_TNP_2017_North_Bic"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-03-13"},"strain_display":{"value":"Côte d'Ivoire/MN346690/2017-03-13"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-179139T","-179140A","-179141T","-179142A","-179143T","-179144A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A"]}}},{"name":"MN346691","node_attrs":{"div":472,"accession":"MN346691","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"Côte d'Ivoire"},"institution":{"value":"Robert Koch Institute, Project Group Epidemiology of Highly Pathogenic Microorganisms"},"strain":{"value":"MPXV_TNP_2017_North_Environmental"},"date":{"value":"2017-03-11"},"strain_display":{"value":"Côte d'Ivoire/MN346691/2017-03-11"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T7005G","A7007T","-179180A","-179181C","-179182A","-196611A"]}}}]}]}]}]}]}]}]}]},{"name":"NODE_0000055","node_attrs":{"div":474,"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C128T","G1687A","C1813A","G1814T","G3099T","G3420A","A4691G","-4694T","-4695T","-6976T","-6978C","G7950T","-8055A","T8286C","C8422T","-8499T","-8993T","C10267A","G10275A","T10641C","C11439T","G11593A","G11624A","G12712A","G12733A","G16788T","T18017A","A18861T","C19055T","T19304A","T20990A","G22575T","C24222T","G24358T","C24719G","G25173T","T25212G","G25407A","T25769G","A27215G","C28090A","T29446C","C29655T","T30500A","A31039G","A31793G","A32364G","C32477A","C33043T","-33199A","-33414T","C33963T","T34005C","G34295A","C34685T","A48148C","C51168T","C55805T","C58467T","C59256T","C67827T","G73821A","C74303G","C74382T","C78728A","A80756G","G81063A","T81182C","G81463T","T82838A","G84333A","C85163T","G86225A","G86535A","G87049A","C87501T","G87735A","C89214T","G89579T","G91023A","A92009G","G92102A","T92237C","A95477C","G95795A","G98430T","G99212A","G99683A","C99830T","C106115T","A107232G","T107394C","G109382A","A109580G","C111716T","T120252C","G120965A","C124737T","C124988G","G126255A","C132719A","-132813T","-133090T","-133091T","-133092T","-133093T","-133094T","-133095T","-133096T","-133097T","-133098T","-133099T","-133100T","-133101T","-133102T","-133177T","-133179T","-133180T","-133181T","-133183T","-133185A","-133186A","G133201A","C133733T","C133966T","G134884A","G135706A","G136498A","-136558G","G136604A","G136687A","G136870A","C143426T","C145803A","A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","C147860T","A148126G","T149765G","C150444T","T150756C","G154405A","-156415A","C156426T","G156512A","-156548A","G156954A","C156978T","T157273G","G157437A","C157490T","-157678A","-157679A","-157680A","-157681A","-157682T","-157683T","-157684T","-157685T","-157686A","-157687A","-157691A","-157692T","-157694A","-157695T","-157696A","-158027A","-158028T","-158029A","C158175A","G158398A","G158403A","G158511A","G158668T","G159415A","A159447C","C160152T","C161574T","G161799A","G162291A","C162828T","C163467T","C164848T","C165304T","G166399T","T167126C","C167858T","C168277A","-168588G","G169603A","G170248A","G170435A","-172087T","G172188A","G172980A","G173150A","-173286A","-173287T","-173288A","-173289T","-173290A","-173291T","-173292A","-173293T","-173294A","-173295T","-173296A","-173297T","-173298A","-173299T","-173300A","-173301T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","C173441T","-173501A","-173502T","-173745T","G173809A","C173810T","T173882C","C174170T","A175065C","C176160T","G177167T","C178275T","G178395A","G178540A","A178887G","-181114A","-181115T","-181116T","-181119T","-181120T","-181121A","-181122T","G181350A","G181994A","G182443A","G182491A","C183008T","G183695A","C183696T","G184137A","T187421C","C188096A","G189418A","-189744T","G189811T","G190098T","A190772C","-192515A","-192516A","T192519C","C193790T","C194111A","C195396A","G195397T","C195523T"],"OPG002":["T313N"],"OPG002_dup":["T313N"],"OPG005":["D74N"],"OPG016":["E121D"],"OPG019":["R124M"],"OPG021":["R230K"],"OPG022":["D73G"],"OPG023":["A426V","A488T"],"OPG031":["K271M"],"OPG036":["E25D"],"OPG040":["A254P","S374Y"],"OPG046":["N95S"],"OPG047":["K232I"],"OPG049":["V37M","M263T"],"OPG054":["G438R"],"OPG074":["V441I"],"OPG094":["T175R"],"OPG105":["G113V","V1070I"],"OPG108":["A4V"],"OPG118":["R256K","S413N","A462V"],"OPG125":["V514I"],"OPG130":["A63T"],"OPG145":["T264I","P348A"],"OPG153":["T355I"],"OPG164":["H217Y"],"OPG172":["T145M"],"OPG185":["A167T","E177D"],"OPG189":["R506C"],"OPG191":["C80F"],"OPG195":["-120C"],"OPG198":["D71N","R133Q"],"OPG204":["K178N"],"OPG205":["R169W"],"OPG210":["R363H","G379D","P781S","A928T"]},"labels":{"aa":"OPG002: T313N; OPG002_dup: T313N; OPG005: D74N; OPG016: E121D; OPG019: R124M; OPG021: R230K; OPG022: D73G; OPG023: A426V, A488T; OPG031: K271M; OPG036: E25D; OPG040: A254P, S374Y; OPG046: N95S; OPG047: K232I; OPG049: V37M, M263T; OPG054: G438R; OPG074: V441I; OPG094: T175R; OPG105: G113V, V1070I; OPG108: A4V; OPG118: R256K, S413N, A462V; OPG125: V514I; OPG130: A63T; OPG145: T264I, P348A; OPG153: T355I; OPG164: H217Y; OPG172: T145M; OPG185: A167T, E177D; OPG189: R506C; OPG191: C80F; OPG195: -120C; OPG198: D71N, R133Q; OPG204: K178N; OPG205: R169W; OPG210: R363H, G379D, P781S, A928T","clade":"clade IIb"}},"children":[{"name":"KJ642617","node_attrs":{"div":481,"accession":"KJ642617","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"Nigeria"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"KJ642617"},"date":{"value":"1971-XX-XX"},"strain_display":{"value":"Nigeria/KJ642617/1971-XX-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G13625A","G98489-","C98727T","T119718C","A129762G","-136555C","G149744A","G160174T","C160852T","A169769-","C169770-","A169771-","A169773-","T169774-","A181253-"],"OPG025":["T548M"],"OPG151":["D280G"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG025: T548M; OPG151: D280G; OPG197: T34-, D35-"}}},{"name":"NODE_0000056","node_attrs":{"div":500,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G3450A","C8893A","G18312A","C19367T","-32210A","-32211C","-32212G","C33143T","G38067A","G46895A","A48138G","C48527A","C53207A","G66580A","C80986T","T92516C","C100562T","T105126C","G128076A","C133145T","-136555T","G137627A","-140134A","-140135A","-140136C","-140137A","-140138A","-140139T","-140140T","-140141A","-140142T","G141300A","C141364T","C142450A","T146687C","A149878G","-158170A","G160867A","-166656T","-166657T","G167656T","-169772G","G171675A","-174531G","-174532A","-174533T","-174534G","-174535A","-174536A","G178423A","A179198-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","-187080T","C193760T","-196615A"],"OPG049":["-314R"],"OPG056":["A323V"],"OPG071":["W411L"],"OPG084":["R620Q"],"OPG104":["A12T"],"OPG150":["D100N"],"OPG153":["T14M"],"OPG159":["-124N","-125Y","-126N"],"OPG161":["E67K","A88V"],"OPG170":["D31G"],"OPG176":["N24D"],"OPG191":["-166F"],"OPG193":["R108I"],"OPG199":["E230K"]},"labels":{"aa":"OPG049: -314R; OPG056: A323V; OPG071: W411L; OPG084: R620Q; OPG104: A12T; OPG150: D100N; OPG153: T14M; OPG159: -124N, -125Y, -126N; OPG161: E67K, A88V; OPG170: D31G; OPG176: N24D; OPG191: -166F; OPG193: R108I; OPG199: E230K","clade":"A"}},"children":[{"name":"MK783031","node_attrs":{"div":504,"accession":"MK783031","author":{"author":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J.","value":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J."},"country":{"value":"Nigeria"},"institution":{"value":"NCEZID/DHCPP/PRB, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MK783031"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-11-09"},"strain_display":{"value":"Nigeria/MK783031/2017-11-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C5157T","G7764A","G9782A","G109736A","C133161T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","G192053A"],"OPG015":["D334N"],"OPG015_dup":["D334N"],"OPG019":["R62K"],"OPG021":["A66T"]},"labels":{"aa":"OPG015: D334N; OPG015_dup: D334N; OPG019: R62K; OPG021: A66T"}}},{"name":"NODE_0000057","node_attrs":{"div":504,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","G18769A","G81977A","G100261A","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","C154408T","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","-196616A","-196617A"],"OPG118":["E606K"]},"labels":{"aa":"OPG118: E606K"}},"children":[{"name":"OP535332","node_attrs":{"div":504,"accession":"OP535332","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2018_5232"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-01-XX"},"strain_display":{"value":"Nigeria/OP535332/2018-01-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C179199-","C179208-","C179217-"]}}},{"name":"NODE_0000058","node_attrs":{"div":505,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C28175T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T"]}},"children":[{"name":"NC_063383.1","node_attrs":{"div":505,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NC_063383","node_attrs":{"div":505,"accession":"NC_063383","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Senkevich,T.G.,Yutin,N.,Wolf,Y.I.,Koonin,E.V.,Moss,B.,Zmasek,C.M.,Knipe,D.M.,Pellett,P.E.,Scheuermann,R.H.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Senkevich,T.G.,Yutin,N.,Wolf,Y.I.,Koonin,E.V.,Moss,B.,Zmasek,C.M.,Knipe,D.M.,Pellett,P.E.,Scheuermann,R.H."},"country":{"value":"Nigeria"},"institution":{"value":"National Center for Biotechnology Information, NIH"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV-M5312_HM12_Rivers"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-08-XX"},"strain_display":{"value":"Nigeria/NC_063383/2018-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000059","node_attrs":{"div":503,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G51559A","C60923T","G179884A"],"OPG080":["E366K"],"OPG208":["E207K"]},"labels":{"aa":"OPG080: E366K; OPG208: E207K"}},"children":[{"name":"MT903337","node_attrs":{"div":505,"accession":"MT903337","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"Nigeria"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV-M2940_FCT"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-XX-XX"},"strain_display":{"value":"Nigeria/MT903337/2018-XX-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","G172784A","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","T181577C"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"OP535334","node_attrs":{"div":507,"accession":"OP535334","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2018_5223"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-02-XX"},"strain_display":{"value":"Nigeria/OP535334/2018-02-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T607-","C101683T","C127245T","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","G178814A","G178988A","C179199-","C179208-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A196615-"],"OPG149":["S17L"]},"labels":{"aa":"OPG149: S17L"}}},{"name":"OP535318","node_attrs":{"div":507,"accession":"OP535318","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2017_5227"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-12-XX"},"strain_display":{"value":"Nigeria/OP535318/2017-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-608T","C23311T","G75512A","G124715A","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","G162165A","C179199-","C179208-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","-196616A"],"OPG039":["E270K"],"OPG095":["R237K"],"OPG145":["D257N"]},"labels":{"aa":"OPG039: E270K; OPG095: R237K; OPG145: D257N"}}},{"name":"NODE_0000060","node_attrs":{"div":504,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A169769-","A169771-","A169773-","T169774-","G177009A","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","A196615-"],"OPG205":["E452K"]},"labels":{"aa":"OPG205: E452K"}},"children":[{"name":"OP535340","node_attrs":{"div":504,"accession":"OP535340","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2017_2888"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-10-XX"},"strain_display":{"value":"Nigeria/OP535340/2017-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C169770-","G169772-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"OP535326","node_attrs":{"div":509,"accession":"OP535326","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2018_5315"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-06-XX"},"strain_display":{"value":"Nigeria/OP535326/2018-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C23000T","G29826A","C109667T","A136552-","T136553-","C136554-","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","G147459A","G155644A","-169769A","-169771A","-169773A","-169774T","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"],"OPG038":["G54S"],"OPG047":["R457C"],"OPG153":["D385-"]},"labels":{"aa":"OPG038: G54S; OPG047: R457C; OPG153: D385-"}}}]}]},{"name":"NODE_0000061","node_attrs":{"div":506,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C8385T","G37209A","G43118A","G48180A","C113841T","A136552-","T136553-","C136554-","C146607T","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","T169721-","A169723-","A169725-","T169726-","A169727-","A169729-","A169731-","T169732-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-"],"OPG056":["S609F"],"OPG133":["G619E"],"OPG153":["D385-"],"OPG170":["E58K"]},"labels":{"aa":"OPG056: S609F; OPG133: G619E; OPG153: D385-; OPG170: E58K"}},"children":[{"name":"OP535328","node_attrs":{"div":506,"accession":"OP535328","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2018_5306"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-03-XX"},"strain_display":{"value":"Nigeria/OP535328/2018-03-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C169722-","G169724-","C169728-","G169730-","C179199-","C179208-","C179217-"],"OPG197":["S18-","D19-","T20-","D21-"]},"labels":{"aa":"OPG197: S18-, D19-, T20-, D21-"}}},{"name":"NODE_0000062","node_attrs":{"div":507,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G29889A","T76087-","A89106-","-169721T","-169723A","-169725A","-169726T","-169727A","-169729A","-169731A","-169732T","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T"],"OPG047":["P436S"]},"labels":{"aa":"OPG047: P436S"}},"children":[{"name":"NODE_0000063","node_attrs":{"div":510,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-","C40251T","C63801T","T121121-","G162243A","-196616A"],"OPG058":["D62N"],"OPG083":["E306K"]},"labels":{"aa":"OPG058: D62N; OPG083: E306K"}},"children":[{"name":"OP612684","node_attrs":{"div":513,"accession":"OP612684","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV/046/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-05-XX"},"strain_display":{"value":"Nigeria/OP612684/2019-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C92830T","A136543-","T136544-","C136545-","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","-173288A","-173289T","G180656A","G186423A","-196617A"],"OPG113":["S367F"],"OPG153":["D382-","D383-","D384-"],"OPG209":["D47N"],"OPG210":["E1690K"]},"labels":{"aa":"OPG113: S367F; OPG153: D382-, D383-, D384-; OPG209: D47N; OPG210: E1690K"}}},{"name":"OP612680","node_attrs":{"div":512,"accession":"OP612680","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV/021/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-04-01"},"strain_display":{"value":"Nigeria/OP612680/2019-04-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C63264T","-89106A","T104748C","T133098-","T133099-","T133100-","T133101-","T133102-","T187080-"],"OPG123":["D108G"]},"labels":{"aa":"OPG123: D108G"}}}]},{"name":"NODE_0000064","node_attrs":{"div":510,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","C28164T","C87027T","G121454A"],"OPG044":["S25F"]},"labels":{"aa":"OPG044: S25F"}},"children":[{"name":"OP612678","node_attrs":{"div":513,"accession":"OP612678","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV/017/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-03-14"},"strain_display":{"value":"Nigeria/OP612678/2019-03-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G46685A","G144659A","G165688A","T187080-","A196614-","A196615-"],"OPG167":["S250F"]},"labels":{"aa":"OPG167: S250F"}}},{"name":"NODE_0000065","node_attrs":{"div":512,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G3531A","-76087T","T151621G","T179068A","-196616A","-196617A"],"OPG178":["F38C"]},"labels":{"aa":"OPG178: F38C"}},"children":[{"name":"OP612675","node_attrs":{"div":513,"accession":"OP612675","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV/007/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-01-30"},"strain_display":{"value":"Nigeria/OP612675/2019-01-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T4676C","-89106A","-136552A","-136553T","-136554C","C193679T"]}}},{"name":"OP612676","node_attrs":{"div":512,"accession":"OP612676","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV/013/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-02-20"},"strain_display":{"value":"Nigeria/OP612676/2019-02-20"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A19360-","A23252-","T133100-","T133101-","T133102-","A138474-","A156769-","T163332-","A173514-","A173515-","G173516-","A173517-","A173518-","G173519-","A173520-","C173521-","G173522-","A173523-","G173524-","G173525-","A173526-","C173527-","G173528-","G173529-","A173530-","G173531-","A173532-","C173533-","G173534-","G173535-","T173536-","A173537-","G173538-","A173539-","A173540-","T173541-","A173542-","A173543-","T179072A"]}}}]}]}]}]},{"name":"NODE_0000066","node_attrs":{"div":501,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G154015A"],"OPG180":["D442N"]},"labels":{"aa":"OPG180: D442N"}},"children":[{"name":"OP535320","node_attrs":{"div":507,"accession":"OP535320","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2017_3008"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-11-XX"},"strain_display":{"value":"Nigeria/OP535320/2017-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-608T","C10430T","G15876A","C18699T","C143669T","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","G180039A","G189317A"],"OPG005":["R40K"],"OPG031":["D44N"],"OPG165":["L52F"],"OPG197":["T34-","D35-"],"OPG208":["M258I"]},"labels":{"aa":"OPG005: R40K; OPG031: D44N; OPG165: L52F; OPG197: T34-, D35-; OPG208: M258I"}}},{"name":"NODE_0000067","node_attrs":{"div":516,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-","C13298T","C18792T","C30636T","C34472T","C34578T","G80099A","G93387A","G114659A","G124031A","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","C148529-","A148530-","T148531-","A148532-","T148533-","C148534-","A148535-","G149265A","C149872T","C161953T","C165782T","G168205A","C177720T","A179194-","T179195-","A179196-","T179197-","C179199-","C179208-","A196614-","A196615-"],"OPG031":["D13N"],"OPG047":["D187N"],"OPG053":["G38E"],"OPG113":["E553K"],"OPG145":["D29N"],"OPG153":["D383-","D384-","D385-"],"OPG174":["S44L","D288-","M289-"],"OPG176":["Q22*"],"OPG188":["H120Y"],"OPG190":["P221S"],"OPG205":["R689C"]},"labels":{"aa":"OPG031: D13N; OPG047: D187N; OPG053: G38E; OPG113: E553K; OPG145: D29N; OPG153: D383-, D384-, D385-; OPG174: S44L, D288-, M289-; OPG176: Q22*; OPG188: H120Y; OPG190: P221S; OPG205: R689C","clade":"A.2"}},"children":[{"name":"ON675438","node_attrs":{"div":538,"accession":"ON675438","author":{"author":"Gigante,C.M.,Griffin-Thomas,L.A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Crain,J.,Li,Y.","value":"Gigante,C.M.,Griffin-Thomas,L.A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Crain,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2"},"strain":{"value":"MPXV_USA_2022_VA001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/ON675438/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-606T","-607T","G11332A","G12099A","C13648T","C15105T","C16227T","C29887T","C42101T","G64216A","G75614A","C117119T","C128534T","G130454A","C134442T","C142918T","G144446A","C156429T","C164832T","C168532T","G174610A","A175231-","T175232-","C175233-","G175234-","T175235-","A175236-","G175237-","T175238-","A175239-","T175240-","C175241-","A175242-","A175243-","G175244-","A175245-","T175246-","G175247-","T175248-","A175249-","A175250-","A175251-","A175252-","T175253-","A175254-","C175255-","T175256-","T175257-","A175258-","C175259-","G175260-","G175261-","T175262-","T175263-","A175264-","T175265-","A175266-","C175267-","C175268-","G175269-","T175270-","C175271-","A175272-","C175273-","A175274-","A175275-","G175276-","A175277-","C175278-","C175279-","A175280-","C175281-","A175282-","G175283-","G175284-","T175285-","T175286-","T175287-","A175288-","A175289-","A175290-","C175291-","T175292-","A175293-","A175294-","T175295-","A175296-","C175297-","T175298-","A175299-","G175300-","A175301-","T175302-","C175303-","C175304-","G175305-","A175306-","A175307-","A175308-","A175309-","T175310-","C175311-","A175312-","A175313-","C175314-","G175315-","T175316-","A175317-","A175318-","C175319-","G175320-","A175321-","T175322-","A175323-","G175324-","G175325-","A175326-","G175327-","A175328-","A175329-","C175330-","C175331-","T175332-","G175333-","C175334-","C175335-","A175336-","A175337-","T175338-","A175339-","T175340-","A175341-","A175342-","C175343-","A175344-","T175345-","G175346-","C175347-","A175348-","G175349-","T175350-","G175351-","C175352-","T175353-","G175354-","T175355-","G175356-","T175357-","C175358-","A175359-","A175360-","C175361-","G175362-","T175363-","C175364-","A175365-","T175366-","T175367-","A175368-","T175369-","T175370-","T175371-","G175372-","T175373-","C175374-","G175375-","A175376-","C175377-","G175378-","A175379-","T175380-","G175381-","T175382-","A175383-","C175384-","T175385-","G175386-","A175387-","T175388-","T175389-","G175390-","A175391-","A175392-","T175393-","G175394-","G175395-","G175396-","A175397-","A175398-","A175399-","A175400-","T175401-","C175402-","C175403-","A175404-","T175405-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A179628G","C179853T","G188544A","-196614A"],"OPG023":["R268*"],"OPG025":["D55N","M540I"],"OPG027":["D51N"],"OPG062":["S52L"],"OPG096":["D10N"],"OPG151":["E511K"],"OPG166":["D17N"],"OPG204":["E27K","I234-","V235-","V236-","S237-","R238-","C239-","K240-","I241-","L242-","T243-","V244-","I245-","P246-","S247-","Q248-","D249-","H250-","R251-","F252-","K253-","L254-","I255-","L256-","D257-","P258-","K259-","I260-","N261-","V262-","T263-","I264-","G265-","E266-","P267-","A268-","N269-","I270-","T271-","C272-","S273-","A274-","V275-","S276-","T277-","S278-","L279-","F280-","V281-","D282-","D283-","V284-","L285-","I286-","E287-","W288-","E289-","N290-","P291-","S292-"]},"labels":{"aa":"OPG023: R268*; OPG025: D55N, M540I; OPG027: D51N; OPG062: S52L; OPG096: D10N; OPG151: E511K; OPG166: D17N; OPG204: E27K, I234-, V235-, V236-, S237-, R238-, C239-, K240-, I241-, L242-, T243-, V244-, I245-, P246-, S247-, Q248-, D249-, H250-, R251-, F252-, K253-, L254-, I255-, L256-, D257-, P258-, K259-, I260-, N261-, V262-, T263-, I264-, G265-, E266-, P267-, A268-, N269-, I270-, T271-, C272-, S273-, A274-, V275-, S276-, T277-, S278-, L279-, F280-, V281-, D282-, D283-, V284-, L285-, I286-, E287-, W288-, E289-, N290-, P291-, S292-"}}},{"name":"OP612689","node_attrs":{"div":517,"accession":"OP612689","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2"},"strain":{"value":"MPXV/111/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-12-17"},"strain_display":{"value":"Nigeria/OP612689/2019-12-17"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G144876A","G173355-","A173356-","G173357-","G173358-","T173359-","A173360-","C173361-","G173362-","G173363-","G173364-","A173365-","T173366-","A173367-","G173368-","A173369-","A173370-","T173371-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A"],"OPG167":["P178S"]},"labels":{"aa":"OPG167: P178S"}}},{"name":"NODE_0000068","node_attrs":{"div":531,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G2752A","G39173A","C57284T","G61844A","C74226T","G118739A","C146223T","G148427A","G150800A","G168365A","G170317A","G172527A","C175759T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G189417A","C189474T","C194458T"],"OPG075":["R72K"],"OPG170":["D186N"],"OPG195":["E46K"],"OPG198":["D94N"],"OPG205":["A35V"]},"labels":{"aa":"OPG075: R72K; OPG170: D186N; OPG195: E46K; OPG198: D94N; OPG205: A35V","clade":"A.2.3"}},"children":[{"name":"ON676707","node_attrs":{"div":534,"accession":"ON676707","author":{"author":"Gigante,C.M.,Stringer,J.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Schulte,J.,Li,Y.","value":"Gigante,C.M.,Stringer,J.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Schulte,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.3"},"strain":{"value":"MPXV_USA_2021_TX"},"host":{"value":"Homo sapiens"},"date":{"value":"2021-07-XX"},"strain_display":{"value":"USA/ON676707/2021-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-606T","C100640T","G142636A","C186104T","-196614A"]}}},{"name":"OP555515","node_attrs":{"div":544,"accession":"OP555515","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.3"},"strain":{"value":"Monkeypox/PT0428/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Portugal/OP555515/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C30669T","C45028T","G49377A","G95355A","C121320T","G136132A","-136546A","-136547T","-136548C","G142265A","C159143T","C162264T","C170573T","C180686T","C181216T","G188229A"],"OPG047":["E176K"],"OPG064":["E291K"],"OPG068":["D393N"],"OPG139":["A17T"],"OPG153":["-383D"],"OPG163":["D22N"],"OPG185":["S76F"],"OPG198":["S179L"],"OPG209":["Q57*"]},"labels":{"aa":"OPG047: E176K; OPG064: E291K; OPG068: D393N; OPG139: A17T; OPG153: -383D; OPG163: D22N; OPG185: S76F; OPG198: S179L; OPG209: Q57*"}}}]},{"name":"NODE_0000069","node_attrs":{"div":536,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G11948A","C14790T","G21991A","G23118A","G38923A","G39515A","G56546A","G57786A","G93312A","C103019T","C112470T","C124129T","C127906T","G135303A","G145902A","C149365T","G155611A","G158424A","G162640A","G186984A"],"OPG023":["S318F"],"OPG025":["D160N"],"OPG037":["S148L"],"OPG056":["R38C"],"OPG113":["V528I"],"OPG122":["H198Y"],"OPG132":["M357I"],"OPG150":["S43L"],"OPG153":["D382-"],"OPG174":["G11R"],"OPG188":["G349S"],"OPG210":["D1877N"]},"labels":{"aa":"OPG023: S318F; OPG025: D160N; OPG037: S148L; OPG056: R38C; OPG113: V528I; OPG122: H198Y; OPG132: M357I; OPG150: S43L; OPG153: D382-; OPG174: G11R; OPG188: G349S; OPG210: D1877N","clade":"A.2.2"}},"children":[{"name":"OP422632","node_attrs":{"div":540,"accession":"OP422632","author":{"author":"Martin,F.,Anges,Y.,Benjamin,H.,Amadou,S.A.,Ousmane,F.","value":"Martin,F.,Anges,Y.,Benjamin,H.,Amadou,S.A.,Ousmane,F."},"country":{"value":"Benin"},"institution":{"value":"Institut Pasteur de Dakar, Virology Department"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.2"},"strain":{"value":"MPXV-SEN0022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Benin/OP422632/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T4619C","C4623-","T4624-","T4625-","T4626-","T4627-","T4628-","C4629-","A4630-","T4631-","A4632-","A4633-","T4634-","T4635-","A4636-","G4637-","A4638-","G4639-","A4640-","A4641-","A4642-","A4643-","A4644-","G4645-","A4646-","T4647-","C4648-","A4649-","A4650-","G4651-","G4652-","T4653-","A4654-","T4655-","A4656-","A4657-","A4658-","A4659-","A4660-","T4661-","T4662-","A4663-","G4664-","A4665-","A4666-","G4667-","T4668-","G4669-","T4670-","T4671-","A4672-","G4673-","A4674-","C4675-","T4676-","A4677-","T4678-","A4679-","A4680-","C32643T","-136546A","-136547T","-136548C","-136549A","-136550T","-136551C","-136552A","-136553T","-136554C","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","G146913-","T146914-","A146915-","-148529C","-148530A","-148531T","-148532A","-148533T","-148534C","-148535A","C156429T","G172501A","T196689-"],"OPG049":["R170K"],"OPG153":["-382D","-383D","-384D","-385D"],"OPG174":["-288D","-289M"],"OPG200":["E118K"]},"labels":{"aa":"OPG049: R170K; OPG153: -382D, -383D, -384D, -385D; OPG174: -288D, -289M; OPG200: E118K"}}},{"name":"OP450997","node_attrs":{"div":543,"accession":"OP450997","author":{"author":"Gigante,C.M.,Xia,D.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y.","value":"Gigante,C.M.,Xia,D.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.2"},"strain":{"value":"MPXV_USA_2022_PA0016"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OP450997/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G451A","G20576A","C20581T","G67351A","G78259A","G94479A","C133402T","A136543-","T136544-","C136545-","C176148T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C196759T"],"OPG036":["E162K"],"OPG085":["S394F"],"OPG205":["H165Y"]},"labels":{"aa":"OPG036: E162K; OPG085: S394F; OPG205: H165Y"}}},{"name":"NODE_0000070","node_attrs":{"div":541,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C13686T","C21861T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G151112A","G174721A","-179212A","-179213T","-179214A","-179215T","-179216A","C188491T"],"OPG025":["E528K"],"OPG037":["M191I"],"OPG204":["A64T"]},"labels":{"aa":"OPG025: E528K; OPG037: M191I; OPG204: A64T"}},"children":[{"name":"OP331336","node_attrs":{"div":545,"accession":"OP331336","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.2"},"strain":{"value":"MPXV_UK_2022_9000166"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-29"},"strain_display":{"value":"United Kingdom/OP331336/2022-06-29"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C27826T","G59282A","C65743A","G85356A","A136543-","T136544-","C136545-"],"OPG043":["E44K"],"OPG084":["P341H"],"OPG106":["S48F"]},"labels":{"aa":"OPG043: E44K; OPG084: P341H; OPG106: S48F"}}},{"name":"OR113690","node_attrs":{"div":551,"accession":"OR113690","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"country":{"value":"Austria"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.2"},"strain":{"value":"hMPXV/Austria/MUW1607960/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-04-05"},"strain_display":{"value":"Austria/OR113690/2023-04-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C18102T","C52429T","C86957T","G97318A","C121394T","G129982A","-136546A","-136547T","-136548C","-136549A","-136552A","-136553T","-136554C","G146714A","C148895A","G165892A","G175471A"],"OPG031":["D243N"],"OPG108":["D35N"],"OPG117":["D424N"],"OPG170":["A22V"],"OPG174":["M167I"],"OPG204":["E314K"]},"labels":{"aa":"OPG031: D243N; OPG108: D35N; OPG117: D424N; OPG170: A22V; OPG174: M167I; OPG204: E314K"}}}]}]},{"name":"NODE_0000071","node_attrs":{"div":517,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-606T","-607T","-608T","C25072T","A136543-","T136544-","C136545-","-179212A","-179213T","-179214A","-179215T","-179216A"],"OPG040":["R136Q"],"OPG153":["D382-"]},"labels":{"aa":"OPG040: R136Q; OPG153: D382-"}},"children":[{"name":"OP612691","node_attrs":{"div":519,"accession":"OP612691","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2"},"strain":{"value":"MPXV/191/20"},"host":{"value":"Homo sapiens"},"date":{"value":"2020-01-XX"},"strain_display":{"value":"Nigeria/OP612691/2020-01-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-609T","C90329T","C132520T","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG111":["S22L"]},"labels":{"aa":"OPG111: S22L"}}},{"name":"NODE_0000072","node_attrs":{"div":530,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G36898A","G42183A","C42903T","G50346A","C54268T","C73616T","G79406A","G105746A","A140492C","C142498T","C157737T","C161152T","A169763-","C169764-","A169765-","G169766-","A169767-","T169768-","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","C179537T","-196614A","-196615A"],"OPG062":["M79I"],"OPG063":["M262I"],"OPG069":["D121N"],"OPG102":["D108N"],"OPG160":["S195A"],"OPG197":["T32-","D33-","T34-","D35-"],"OPG208":["S91L"]},"labels":{"aa":"OPG062: M79I; OPG063: M262I; OPG069: D121N; OPG102: D108N; OPG160: S195A; OPG197: T32-, D33-, T34-, D35-; OPG208: S91L","clade":"A.2.1"}},"children":[{"name":"NODE_0000073","node_attrs":{"div":531,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T95936A"],"OPG116":["D192E"]},"labels":{"aa":"OPG116: D192E"}},"children":[{"name":"ON674051","node_attrs":{"div":533,"accession":"ON674051","author":{"author":"Gigante,C.M.,Lee,P.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"strain":{"value":"MPXV_USA_2022_FL001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/ON674051/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T608-","C112544T","G163540A"],"OPG132":["D333N"],"OPG189":["E70K"]},"labels":{"aa":"OPG132: D333N; OPG189: E70K"}}},{"name":"OR459777","node_attrs":{"div":539,"accession":"OR459777","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"country":{"value":"South Korea"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"strain":{"value":"MPXV-ROK-P004-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-22"},"strain_display":{"value":"South Korea/OR459777/2022-11-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["-609T","A46522G","G52289A","G67261A","C72231T","C115379T","C135822T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G181947A","G182189A","-196616A","-196617A"],"OPG071":["T717I"],"OPG085":["S424L"],"OPG210":["D198N"]},"labels":{"aa":"OPG071: T717I; OPG085: S424L; OPG210: D198N"}}}]},{"name":"NODE_0000074","node_attrs":{"div":531,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C184924T","-196616A","-196617A"],"OPG210":["S1190L"]},"labels":{"aa":"OPG210: S1190L"}},"children":[{"name":"OP936000","node_attrs":{"div":540,"accession":"OP936000","author":{"author":"Nguyen,D.T.,Le,H.M.,Huynh,H.T.T.,Tang,T.C.,Le,N.H.,Nguyen,H.H.,Nghiem,N.M.,Nguyen,H.T.T.,Vo,Q.T.,Vu,T.T.K.,Nguyen,T.T.,Phan,T.V.,Nguyen,T.L.N.,Le,T.M.,Vo,Q.M.,Dinh,M.N.H.,Nguyen,P.T.,Tran,P.T.L.,Tran,T.T.T.,Pham,T.T.N.,Nguyen,T.H.,Truong,L.T.T.,Nguyen,H.N.T.,Tran,T.T.,Le,K.T.T.,Lam,Y.M.,Thwaites,G.,Thwaites,L.,Nguyen,C.V.V.,Nguyen,A.T.,Le,T.V.","value":"Nguyen,D.T.,Le,H.M.,Huynh,H.T.T.,Tang,T.C.,Le,N.H.,Nguyen,H.H.,Nghiem,N.M.,Nguyen,H.T.T.,Vo,Q.T.,Vu,T.T.K.,Nguyen,T.T.,Phan,T.V.,Nguyen,T.L.N.,Le,T.M.,Vo,Q.M.,Dinh,M.N.H.,Nguyen,P.T.,Tran,P.T.L.,Tran,T.T.T.,Pham,T.T.N.,Nguyen,T.H.,Truong,L.T.T.,Nguyen,H.N.T.,Tran,T.T.,Le,K.T.T.,Lam,Y.M.,Thwaites,G.,Thwaites,L.,Nguyen,C.V.V.,Nguyen,A.T.,Le,T.V."},"country":{"value":"Vietnam"},"institution":{"value":"EI group, Oxford University Clinica Research Unit"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"strain":{"value":"Mpox-HCMC-M157"},"date":{"value":"2022-09-26"},"strain_display":{"value":"Vietnam/OP936000/2022-09-26"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["T647-","G648-","C32252T","G51559A","A86823T","G103706A","C152033T","T167015G","A167020T","A167021-","C167022-","G167029C","A187574C"]}}},{"name":"NODE_0000075","node_attrs":{"div":532,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G43103A","A136540-","T136541-","C136542-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"],"OPG063":["P196S"],"OPG153":["D381-"]},"labels":{"aa":"OPG063: P196S; OPG153: D381-"}},"children":[{"name":"OR455100","node_attrs":{"div":538,"accession":"OR455100","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"strain":{"value":"MpxV/human/USA/WA-UW-081251/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-08-XX"},"strain_display":{"value":"USA/OR455100/2023-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-609T","C29438T","G58696A","G120906A","G147352A","G178102A","C187942T","A192392-","A192393-","A192394-","T192395-","G192396-","A192397-","G192398-","T192399-","T192400-","A192401-","A192402-","T192403-","A192404-","G192405-"],"OPG046":["V98I"],"OPG078":["S39L"],"OPG138":["S76F"],"OPG171":["R122K"]},"labels":{"aa":"OPG046: V98I; OPG078: S39L; OPG138: S76F; OPG171: R122K"}}},{"name":"NODE_0000076","node_attrs":{"div":534,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G30868A","G102599A","-133098T","-133099T","-133100T","-169763A","-169764C","-169765A","-169766G","-169767A","-169768T","-169769A","-169770C","-169771A","-169772G","-169773A","-169774T"],"OPG122":["D58N"],"OPG197":["-32T","-33D","-34T","-35D"]},"labels":{"aa":"OPG122: D58N; OPG197: -32T, -33D, -34T, -35D"}},"children":[{"name":"OP331335","node_attrs":{"div":535,"accession":"OP331335","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"strain":{"value":"MPXV_UK_2022_9000155"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-03"},"strain_display":{"value":"United Kingdom/OP331335/2022-06-03"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T607-","T608-","-133101T","-133102T","-136540A","-136541T","-136542C","-136543A","-136544T","-136545C","-136546A","-136547T","-136548C","-136549A","-136550T","-136551C","-136552A","-136553T","-136554C","C164210T","-174531G","-174532A","-174533T","-174534G","-174535A","-174536A"],"OPG153":["-381D","-382D","-383D","-384D","-385D"],"OPG189":["S293L"]},"labels":{"aa":"OPG153: -381D, -382D, -383D, -384D, -385D; OPG189: S293L"}}},{"name":"OP605572","node_attrs":{"div":534,"accession":"OP605572","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"strain":{"value":"Slovenia-MPXV-30-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Slovenia/OP605572/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C165-","A196625-","T196626-","T196627-"]}}}]}]}]}]}]}]}]},{"name":"NODE_0000077","node_attrs":{"div":501,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A173314-","T173315-","A173316-","T173317-","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","C187428T"]}},"children":[{"name":"NODE_0000078","node_attrs":{"div":509,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G56968A","G61844A","C84008T","G96841A","C100971T","C134078T","C151050T","G188889-"],"OPG074":["S53L"],"OPG117":["D265N"],"OPG120":["E260K"]},"labels":{"aa":"OPG074: S53L; OPG117: D265N; OPG120: E260K","clade":"A.3"}},"children":[{"name":"MG693723","node_attrs":{"div":522,"accession":"MG693723","author":{"author":"Faye,O.,Pratt,C.B.,Faye,M.,Fall,G.,Chitty,J.A.,Diagne,M.M.,Wiley,M.R.,Yinka-Ogunleye,A.F.,Aruna,S.,Etebu,E.N.,Aworabhi,N.,Ogoina,D.,Numbere,W.,Mba,N.,Palacios,G.,Sall,A.A.,Ihekweazu,C.,Diagne,M.,Palacios,G.F.,Sall,A.","value":"Faye,O.,Pratt,C.B.,Faye,M.,Fall,G.,Chitty,J.A.,Diagne,M.M.,Wiley,M.R.,Yinka-Ogunleye,A.F.,Aruna,S.,Etebu,E.N.,Aworabhi,N.,Ogoina,D.,Numbere,W.,Mba,N.,Palacios,G.,Sall,A.A.,Ihekweazu,C.,Diagne,M.,Palacios,G.F.,Sall,A."},"country":{"value":"Nigeria"},"institution":{"value":"USAMRIID, Center for Genome Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"strain":{"value":"MPXV_Nig_2017_297957"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-XX-XX"},"strain_display":{"value":"Nigeria/MG693723/2017-XX-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A8143-","G8144-","C8145-","A8146-","T8147-","A8148-","T8149-","T8150-","A8151-","A8152-","A8153-","G8154-","T8155-","A8156-","A8157-","A8158-","A8159-","T8160-","C8161-","T8162-","A8163-","G8164-","T8165-","T8166-","A8167-","C8168-","C8169-","T8170-","T8171-","G8172-","A8173-","A8174-","A8175-","A8176-","T8177-","G8178-","A8179-","A8180-","T8181-","A8182-","C8183-","A8184-","G8185-","T8186-","G8187-","G8188-","G8189-","T8190-","G8191-","G8192-","T8193-","T8194-","C8195-","C8196-","G8197-","T8198-","A8199-","T8200-","C8201-","A8202-","C8203-","C8204-","A8205-","G8206-","T8207-","A8208-","A8209-","G8210-","A8211-","A8212-","C8213-","A8214-","T8215-","A8216-","A8217-","T8218-","A8219-","G8220-","T8221-","C8222-","G8223-","A8224-","A8225-","T8226-","A8227-","C8228-","A8229-","G8230-","T8231-","A8232-","T8233-","C8234-","C8235-","G8236-","A8237-","T8238-","T8239-","G8240-","A8241-","G8242-","A8243-","T8244-","T8245-","T8246-","T8247-","G8248-","C8249-","A8250-","T8251-","A8252-","C8253-","A8254-","A8255-","T8256-","A8257-","C8258-","T8259-","A8260-","G8261-","T8262-","C8263-","T8264-","A8265-","G8266-","A8267-","A8268-","A8269-","G8270-","A8271-","A8272-","A8273-","T8274-","T8275-","T8276-","G8277-","T8278-","A8279-","A8280-","T8281-","C8282-","A8283-","T8284-","C8285-","C8286-","T8287-","C8288-","T8289-","G8290-","T8291-","G8292-","A8293-","C8294-","A8295-","G8296-","G8297-","A8298-","G8299-","T8300-","C8301-","C8302-","A8303-","T8304-","A8305-","T8306-","A8307-","T8308-","C8309-","T8310-","G8311-","T8312-","A8313-","T8314-","C8315-","A8316-","T8317-","C8318-","G8319-","T8320-","C8321-","T8322-","A8323-","G8324-","T8325-","T8326-","T8327-","T8328-","T8329-","A8330-","T8331-","C8332-","A8333-","G8334-","T8335-","G8336-","T8337-","C8338-","C8339-","T8340-","A8341-","T8342-","G8343-","C8344-","T8345-","A8346-","T8347-","A8348-","T8349-","T8350-","C8351-","C8352-","T8353-","G8354-","T8355-","T8356-","A8357-","T8358-","C8359-","A8360-","T8361-","C8362-","A8363-","T8364-","T8365-","A8366-","G8367-","T8368-","T8369-","A8370-","A8371-","T8372-","G8373-","A8374-","A8375-","A8376-","A8377-","T8378-","A8379-","A8380-","C8381-","T8382-","C8383-","T8384-","C8385-","G8386-","T8387-","G8388-","C8389-","T8390-","T8391-","C8392-","A8393-","G8394-","A8395-","A8396-","A8397-","A8398-","G8399-","T8400-","C8401-","A8402-","A8403-","A8404-","T8405-","A8406-","T8407-","T8408-","G8409-","T8410-","A8411-","T8412-","C8413-","C8414-","A8415-","T8416-","A8417-","C8418-","A8419-","T8420-","A8421-","T8422-","A8423-","T8424-","C8425-","T8426-","C8427-","C8428-","A8429-","A8430-","A8431-","A8432-","C8433-","T8434-","A8435-","T8436-","C8437-","A8438-","C8439-","T8440-","T8441-","A8442-","T8443-","A8444-","C8445-","G8446-","T8447-","T8448-","T8449-","A8450-","T8451-","C8452-","T8453-","T8454-","T8455-","A8456-","A8457-","C8458-","G8459-","A8460-","A8461-","C8462-","A8463-","T8464-","A8465-","T8466-","A8467-","C8468-","C8469-","T8470-","A8471-","G8472-","A8473-","T8474-","G8475-","G8476-","T8477-","T8478-","A8479-","T8480-","T8481-","T8482-","A8483-","C8484-","T8485-","A8486-","A8487-","C8488-","A8489-","G8490-","A8491-","C8492-","A8493-","T8494-","T8495-","T8496-","T8497-","T8498-","T8499-","C8500-","A8501-","A8502-","G8503-","A8504-","T8505-","C8506-","T8507-","A8508-","T8509-","T8510-","G8511-","A8512-","C8513-","A8514-","A8515-","T8516-","A8517-","A8518-","C8519-","T8520-","C8521-","C8522-","T8523-","A8524-","T8525-","A8526-","G8527-","T8528-","T8529-","T8530-","C8531-","C8532-","A8533-","C8534-","A8535-","T8536-","C8537-","A8538-","A8539-","C8540-","C8541-","A8542-","A8543-","G8544-","T8545-","A8546-","A8547-","T8548-","G8549-","A8550-","T8551-","C8552-","A8553-","T8554-","C8555-","T8556-","A8557-","T8558-","T8559-","G8560-","T8561-","T8562-","A8563-","T8564-","A8565-","T8566-","A8567-","A8568-","C8569-","A8570-","A8571-","T8572-","A8573-","A8574-","C8575-","A8576-","T8577-","A8578-","A8579-","C8580-","T8581-","C8582-","T8583-","T8584-","T8585-","T8586-","C8587-","C8588-","A8589-","T8590-","T8591-","T8592-","T8593-","T8594-","A8595-","T8596-","C8597-","A8598-","G8599-","T8600-","A8601-","T8602-","C8603-","T8604-","A8605-","T8606-","A8607-","T8608-","C8609-","A8610-","A8611-","C8612-","G8613-","T8614-","C8615-","G8616-","T8617-","T8618-","G8619-","T8620-","A8621-","G8622-","T8623-","G8624-","A8625-","A8626-","T8627-","A8628-","G8629-","T8630-","A8631-","G8632-","T8633-","C8634-","A8635-","T8636-","T8637-","G8638-","A8639-","T8640-","C8641-","T8642-","A8643-","T8644-","T8645-","A8646-","T8647-","A8648-","T8649-","G8650-","A8651-","A8652-","A8653-","C8654-","G8655-","G8656-","A8657-","T8658-","A8659-","T8660-","G8661-","T8662-","C8663-","T8664-","A8665-","G8666-","T8667-","T8668-","A8669-","A8670-","T8671-","A8672-","T8673-","T8674-","T8675-","T8676-","C8677-","T8678-","T8679-","T8680-","G8681-","A8682-","T8683-","T8684-","T8685-","A8686-","A8687-","A8688-","G8689-","T8690-","C8691-","T8692-","A8693-","T8694-","A8695-","G8696-","T8697-","C8698-","T8699-","T8700-","T8701-","A8702-","C8703-","A8704-","A8705-","A8706-","C8707-","A8708-","T8709-","A8710-","A8711-","T8712-","A8713-","T8714-","C8715-","C8716-","T8717-","T8718-","A8719-","T8720-","C8721-","C8722-","G8723-","A8724-","C8725-","T8726-","T8727-","T8728-","A8729-","T8730-","A8731-","T8732-","T8733-","T8734-","C8735-","C8736-","T8737-","G8738-","T8739-","A8740-","G8741-","G8742-","G8743-","T8744-","G8745-","G8746-","C8747-","A8748-","T8749-","A8750-","A8751-","T8752-","T8753-","T8754-","T8755-","A8756-","T8757-","T8758-","C8759-","T8760-","G8761-","C8762-","C8763-","T8764-","C8765-","C8766-","A8767-","C8768-","A8769-","A8770-","T8771-","C8772-","A8773-","G8774-","T8775-","G8776-","T8777-","T8778-","T8779-","C8780-","C8781-","A8782-","A8783-","A8784-","T8785-","A8786-","T8787-","A8788-","T8789-","T8790-","A8791-","C8792-","T8793-","A8794-","G8795-","A8796-","C8797-","A8798-","A8799-","T8800-","A8801-","T8802-","T8803-","C8804-","C8805-","A8806-","T8807-","A8808-","T8809-","A8810-","G8811-","T8812-","T8813-","A8814-","T8815-","T8816-","A8817-","G8818-","T8819-","T8820-","A8821-","A8822-","G8823-","G8824-","G8825-","A8826-","C8827-","C8828-","C8829-","A8830-","A8831-","T8832-","T8833-","A8834-","G8835-","A8836-","A8837-","C8838-","A8839-","C8840-","G8841-","T8842-","A8843-","C8844-","G8845-","C8846-","G8847-","C8848-","T8849-","T8850-","A8851-","T8852-","T8853-","C8854-","A8855-","T8856-","C8857-","A8858-","T8859-","T8860-","T8861-","G8862-","G8863-","A8864-","T8865-","C8866-","G8867-","T8868-","A8869-","T8870-","T8871-","T8872-","C8873-","A8874-","T8875-","A8876-","A8877-","A8878-","A8879-","G8880-","T8881-","T8882-","A8883-","T8884-","T8885-","A8886-","T8887-","G8888-","T8889-","T8890-","A8891-","T8892-","A8893-","G8894-","A8895-","T8896-","G8897-","T8898-","C8899-","A8900-","A8901-","C8902-","A8903-","C8904-","A8905-","T8906-","T8907-","C8908-","T8909-","A8910-","C8911-","A8912-","T8913-","T8914-","T8915-","T8916-","T8917-","T8918-","T8919-","A8920-","A8921-","T8922-","T8923-","G8924-","T8925-","C8926-","T8927-","A8928-","T8929-","A8930-","T8931-","A8932-","G8933-","T8934-","A8935-","T8936-","T8937-","T8938-","T8939-","T8940-","C8941-","T8942-","G8943-","A8944-","T8945-","A8946-","T8947-","T8948-","T8949-","T8950-","C8951-","T8952-","A8953-","T8954-","A8955-","A8956-","T8957-","A8958-","T8959-","C8960-","A8961-","G8962-","A8963-","A8964-","T8965-","T8966-","G8967-","T8968-","C8969-","T8970-","T8971-","C8972-","C8973-","A8974-","T8975-","A8976-","G8977-","G8978-","A8979-","A8980-","G8981-","T8982-","T8983-","G8984-","T8985-","A8986-","T8987-","A8988-","C8989-","T8990-","A8991-","T8992-","T8993-","C8994-","G8995-","G8996-","A8997-","A8998-","T8999-","C9000-","A9001-","G9002-","T9003-","T9004-","A9005-","C9006-","A9007-","T9008-","G9009-","T9010-","T9011-","T9012-","A9013-","A9014-","A9015-","T9016-","A9017-","A9018-","T9019-","T9020-","C9021-","T9022-","C9023-","T9024-","G9025-","A9026-","T9027-","G9028-","T9029-","C9030-","A9031-","T9032-","T9033-","C9034-","C9035-","T9036-","T9037-","A9038-","T9039-","A9040-","C9041-","A9042-","A9043-","T9044-","C9045-","A9046-","A9047-","A9048-","T9049-","T9050-","C9051-","A9052-","T9053-","T9054-","A9055-","T9056-","T9057-","A9058-","A9059-","A9060-","C9061-","A9062-","G9063-","T9064-","T9065-","T9066-","A9067-","A9068-","T9069-","A9070-","G9071-","T9072-","C9073-","T9074-","G9075-","T9076-","A9077-","G9078-","A9079-","C9080-","C9081-","T9082-","T9083-","T9084-","A9085-","T9086-","C9087-","G9088-","T9089-","C9090-","G9091-","T9092-","A9093-","C9094-","A9095-","T9096-","A9097-","T9098-","C9099-","C9100-","A9101-","T9102-","T9103-","G9104-","T9105-","C9106-","T9107-","T9108-","A9109-","T9110-","T9111-","A9112-","G9113-","T9114-","T9115-","A9116-","C9117-","G9118-","C9119-","T9120-","T9121-","A9122-","T9123-","T9124-","T9125-","T9126-","T9127-","A9128-","T9129-","G9130-","G9131-","G9132-","T9133-","T9134-","T9135-","T9136-","A9137-","C9138-","G9139-","T9140-","T9141-","G9142-","C9143-","T9144-","T9145-","T9146-","A9147-","T9148-","T9149-","A9150-","T9151-","A9152-","T9153-","T9154-","T9155-","T9156-","A9157-","T9158-","A9159-","A9160-","T9161-","A9162-","A9163-","T9164-","G9165-","A9166-","T9167-","T9168-","G9169-","T9170-","T9171-","T9172-","G9173-","A9174-","C9175-","A9176-","A9177-","T9178-","G9179-","T9180-","C9181-","G9182-","T9183-","A9184-","G9185-","T9186-","A9187-","T9188-","A9189-","G9190-","A9191-","T9192-","A9193-","T9194-","A9195-","T9196-","T9197-","A9198-","T9199-","T9200-","A9201-","G9202-","A9203-","G9204-","G9205-","A9206-","G9207-","G9208-","T9209-","A9210-","T9211-","A9212-","A9213-","T9214-","T9215-","A9216-","T9217-","A9218-","A9219-","A9220-","A9221-","A9222-","G9223-","T9224-","T9225-","T9226-","C9227-","T9228-","G9229-","A9230-","G9231-","T9232-","A9233-","C9234-","G9235-","A9236-","T9237-","G9238-","T9239-","T9240-","A9241-","T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","C9257-","A9258-","T9259-","T9260-","A9261-","A9262-","C9263-","A9264-","T9265-","C53702T","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","A166866-","C166867-","T166868-","G166869-","A166870-","T166871-","G166872-","A166873-","T166874-","A166875-","A166876-","T166877-","A166878-","A166879-","T166880-","G166881-","A166882-","A166883-","T166884-","T166885-","G166886-","G166887-","T166888-","G166889-","T166890-","T166891-","A166892-","A166893-","A166894-","T166895-","T166896-","T166897-","T166898-","A166899-","A166900-","A166901-","G166902-","A166903-","G166904-","T166905-","A166906-","C166907-","A166908-","C166909-","A166910-","A166911-","T166912-","T166913-","T166914-","C166915-","T166916-","A166917-","T166918-","T166919-","A166920-","T166921-","T166922-","A166923-","C166924-","A166925-","G166926-","A166927-","G166928-","T166929-","C166930-","A166931-","T166932-","G166933-","T166934-","G166935-","A166936-","C166937-","G166938-","T166939-","C166940-","G166941-","G166942-","A166943-","T166944-","T166945-","T166946-","G166947-","A166948-","T166949-","T166950-","C166951-","C166952-","A166953-","T166954-","A166955-","G166956-","A166957-","T166958-","A166959-","T166960-","A166961-","G166962-","A166963-","T166964-","G166965-","T166966-","T166967-","A166968-","T166969-","A166970-","A166971-","A166972-","C166973-","G166974-","A166975-","C166976-","T166977-","A166978-","T166979-","A166980-","A166981-","A166982-","A166983-","T166984-","T166985-","A166986-","T166987-","T166988-","G166989-","A166990-","T166991-","A166992-","T166993-","G166994-","T166995-","A166996-","T166997-","A166998-","C166999-","C168582A","C168584-","T168585-","C168586-","T168587-","G168588-","T168589-","A168590-","T168591-","T168592-","T168593-","C168594-","T168595-","G168596-","T168597-","A168598-","T168599-","A168600-","T168601-","T168602-","G168603-","T168604-","G168605-","A168606-","T168607-","C168608-","A168609-","A168610-","G168611-","A168612-","G168613-","G168614-","C168615-","G168616-","G168617-","G168618-","A168619-","G168620-","T168624G","A168626-","A168627-","A168628-","T168629-","T168630-","T168631-","G168632-","A168633-","G168634-","G168635-","A168636-","G168637-","T168638-","A168639-","T168640-","A168641-","C168642-","T168643-","C168644-","A168645-","A168646-","G168647-","A168648-","A168649-","T168650-","C168651-","A168652-","A168653-","G168654-","T168655-","G168656-","A168657-","T168658-","A168659-","T168660-","C168661-","A168662-","G168663-","T168664-","A168665-","T168666-","T168667-","A168668-","A168674-","A168675-","G168676-","T168677-","A168678-","T168679-","G168680-","A168681-","T168682-","T168683-","C168684-","A168685-","T168686-","C168687-","A168688-","T168689-","G168690-","T168691-","A168692-","T168693-","T168694-","G168695-","A168696-","T168697-","T168698-","A168699-","T168700-","G168704-","G168705-","T168706-","A168707-","T168708-","T168709-","A168710-","A168711-","T168712-","C168713-","A168714-","A168715-","A168716-","G168717-","T168718-","T168719-","T168720-","C168721-","A168722-","T168723-","G168724-","A168725-","A168726-","T168727-","T168731C","G168732A","A168734T","C168737G","G168741-","A168742-","A168743-","T168744-","A168748T","C168750G","G168755-","A168756-","T168757-","A168758-","G168759-","A168760-","G168761-","A168762-","A168763-","T168764-","C168765-","A168766-","T168767-","G168768-","C168769-","G168770-","T168771-","C168772-","A168773-","G168774-","A168775-","T168777G","C169569-","A169570-","T169571-","T169572-","T169573-","A169574-","A169575-","T169576-","A169577-","A169578-","G169579-","G169580-","A169581-","C169582-","A169583-","T169584-","T169585-","G169586-","G169587-","A169588-","T169589-","A169590-","T169591-","G169592-","T169593-","G169594-","G169595-","A169596-","A169597-","A169598-","A169599-","G169600-","T169601-","G169602-","A169603-","T169604-","G169605-","T169606-","A169607-","T169608-","G169609-","G169610-","A169611-","A169612-","G169613-","T169614-","T169615-","A169616-","G169617-","T169618-","A169619-","C169620-","A169621-","T169622-","T169623-","A169624-","T169625-","C169626-","A169627-","A169628-","C169629-","T169630-","T169631-","C169632-","T169633-","C169634-","C169635-","T169636-","T169637-","A169638-","T169639-","T169640-","G169641-","A169642-","T169643-","T169644-","G169645-","A169646-","A169647-","A169648-","A169649-","T169650-","G169651-","A169652-","A169653-","A169654-","A169655-","T169656-","A169657-","T169658-","A169659-","A169660-","A169661-","T169662-","A169663-","G169664-","T169665-","T169666-","T169667-","T169668-","T169669-","A169670-","T169671-","G169672-","T169673-","A169674-","T169675-","A169676-","G169677-","C169678-","G169679-","G169680-","T169681-","A169682-","T169683-","C169684-","T169685-","A169686-","C169687-","C169688-","C169689-","T169690-","A169691-","T169692-","A169693-","G169694-","T169695-","T169696-","T169697-","T169698-","A169699-","T169700-","T169701-","G169702-","C169703-","T169704-","T169705-","A169706-","C169707-","T169708-","A169709-","C169710-","T169711-","A169712-","A169713-","C169714-","A169715-","T169716-","G169717-","G169718-","A169719-","T169720-","T169721-","C169722-","A169723-","G169724-","A169725-","T169726-","A169727-","C169728-","A169729-","G169730-","A169731-","T169732-","A169733-","C169734-","A169735-","G169736-","A169737-","T169738-","A169739-","C169740-","A169741-","G169742-","A169743-","T169744-","A169745-","C169746-","A169747-","G169748-","A169749-","T169750-","A169751-","C169752-","A169753-","G169754-","A169755-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","T187263G","A187265-","G187266-","A187267-","A187268-","T187269-","C187270-","A187271-","T187272-","T187273-","T187274-","A187275-","T187276-","C187277-","A187278-","T187279-","A187280-","A187281-","C187282-","T187283-","A187284-","T187285-","G187286-","T187287-","T187288-","T187289-","A187290-","A187291-","T187292-","A187293-","A187294-","A187295-","T187296-","T187297-","C187298-","A187299-","T187300-","C187301-","A187302-","A187303-","C187304-","G187305-","A187306-","A187307-","T187308-","A187309-","T187310-","C187311-","G187312-","A187313-","T187314-","A187315-","A187316-","A187317-","G187318-","A187319-","C187320-","C187321-","T187322-","C187323-","T187324-","T187325-","G187326-","T187327-","A187328-","A187329-","T187330-","T187331-","C187332-","G187333-","A187334-","G187335-","T187336-","A187337-","T187338-","A187339-","G187340-","G187341-","A187342-","A187343-","G187344-","T187345-","A187346-","G187347-","T187348-","A187349-","T187350-","T187351-","A187352-","C187353-","C187354-","A187355-","T187356-","A187357-","T187358-","C187359-","A187360-","A187361-","C187362-","C187366T","A187372-","A187373-","C187374-","A187375-","A187376-","T187377-","T187378-","A187379-","C187380-","T187381-","C187382-","T187383-","A187384-","A187385-","A187386-","A187387-","C187388-","A187389-","T187390-","G187391-","A187392-","G187393-","G187394-","A187395-","T187396-","T187397-","G187398-","T187399-","A187400-","C187401-","T187402-","C187403-","C187404-","T187405-","G187406-","T187407-","C187408-","T187409-","T187410-","G187415-","G187416-","A187417-","G187418-","A187419-","T187420-","C187421-","A187422-","C187423-","T187424-","A187425-","T187426-","T187427-","T187428-","A187429-","G187430-","T187431-","C187432-","G187433-","T187434-","T187435-","G187436-","A187437-","T187438-","A187439-","A187440-","A187441-","C187442-","T187443-","A187444-","G187445-","T187446-","A187447-","A187448-","C187449-","C187450-","T187451-","C187452-","A187453-","G187454-","G187455-","T187456-","T187457-","T187458-","C187459-","T187460-","T187461-","T187462-","A187463-","C187464-","A187465-","A187466-","A187467-","C187468-","G187469-","A187470-","T187471-","A187472-","A187473-","A187474-","G187475-","T187476-","A187477-","C187478-","A187479-","A187480-","C187481-","A187482-","T187483-","C187484-","A187485-","A187486-","G187487-","A187488-","C187489-","C187490-","T187491-","C187492-","A187493-","C187494-","A187495-","A187496-","C187497-","A187498-","C187499-","A187500-","G187501-","T187502-","G187503-","C187504-","A187505-","A187506-","G187507-","A187508-","T187509-","T187510-","A187511-","A187512-","T187513-","C187514-","T187515-","A187516-","G187517-","A187518-","A187519-","A187520-","T187521-","C187522-","A187523-","A187524-","A187525-","T187526-","G187527-","T187528-","A187529-","A187530-","T187531-","T187532-","C187533-","T187534-","G187535-","G187536-","A187537-","G187538-","G187539-","C187545-","T187546-","A187547-","G187548-","A187549-","C187550-","A187551-","A187552-","C187553-","T187554-","A187555-","A187556-","C187557-","A187558-","C187559-","C187560-","C187561-","A187562-","C187563-","G187564-","G187565-","C187566-","G187567-","A187568-","A187569-","G187570-","T187571-","A187572-","T187573-","A187574-","C187575-","T187576-","T187577-","T187578-","A187579-","T187580-","G187581-","C187582-","C187583-","T187584-","C187585-","A187586-","T187587-","T187588-","C187589-","A187590-","G187591-","A187592-","A187593-","A187594-","C187595-","G187596-","G187597-","T187598-","A187599-","A187600-","C187601-","T187602-","G187603-","T187604-","A187605-","G187606-","T187607-","A187608-","G187609-","G187610-","A187611-","G187612-","A187613-","C187614-","T187615-","G187616-","T187617-","C187618-","T187619-","C187620-","T187621-","C187622-","T187623-","A187624-","A187625-","T187626-","C187627-","T187628-","C187629-","G187630-","A187631-","T187632-","G187633-","T187634-","A187635-","T187636-","A187637-","T187638-","A187639-","T187640-","A187641-","A187642-","T187643-","A187644-","T187645-","A187646-","T187647-","A187648-","C187649-","C187650-","A187651-","A187652-","T187653-","A187654-","C187655-","G187656-","G187657-","A187658-","C187659-","G187660-","C187661-","G187662-","A187663-","T187664-","A187665-","T187666-","A187667-","T187668-","T187669-","C187670-","C187671-","G187672-","A187673-","C187674-","A187675-","T187676-","G187677-","A187678-","A187679-","T187680-","G187681-","G187682-","C187683-","G187684-","T187685-","C187686-","G187687-","C187688-","T187689-","T187690-","A187691-","T187692-","C187693-","A187694-","T187695-","A187696-","T187697-","G187698-","T187699-","T187700-","A187701-","T187702-","A187703-","T187704-","C187705-","C187706-","T187707-","A187708-","A187709-","A187710-","T187711-","G187712-","T187713-","T187714-","G187715-","A187716-","T187717-","C187718-","A187719-","T187720-","A187721-","T187722-","T187723-","C187724-","C187725-","A187726-","C187727-","A187728-","A187729-","A187730-","T187731-","G187732-","A187733-","T187734-","T187735-","G187736-","T187737-","G187738-","A187739-","A187740-","C187741-","G187742-","A187743-","G187744-","A187745-","T187746-","T187747-","A187748-","A187749-","A187750-","T187751-","C187752-","A187753-","T187754-","C187755-","T187756-","A187757-","A187758-","C187759-","A187760-","A187761-","A187762-","T187763-","A187764-","A187765-","T187766-","T187767-","A187768-","G187769-","T187770-","T187771-","T187772-","T187773-","T187774-","T187775-","A187776-","T187777-","G187778-","A187779-","C187780-","A187781-","T187782-","T187783-","A187784-","A187785-","C187786-","A187787-","T187788-","A187789-","T187790-","A187791-","A187792-","T187793-","A187794-","A187795-","A187796-","T187797-","A187798-","A187799-","A187800-","T187801-","T187802-","A187803-","A187804-","T187805-","C187806-","A187807-","T187808-","T187809-","A187810-","T187811-","T187812-","G187813-","A187814-","C187815-","T187816-","T187817-","A187818-","A187819-","C187820-","G187821-","A187822-","T187823-","G187824-","A187825-","C187826-","G187827-","A187828-","A187829-","A187830-","G187831-","T187832-","T187833-","A187834-","T187835-","C187836-","A187837-","T187838-","T187839-","A187840-","T187841-","C187842-","T187843-","T187844-","A187845-","G187846-","G187847-","A187848-","T187849-","T187850-","C187851-","T187852-","T187853-","G187854-","A187855-","T187856-","T187857-","A187858-","T187859-","T187860-","A187861-","A187862-","T187863-","A187864-","C187865-","A187866-","A187867-","A187868-","T187869-","T187870-","C187871-","G187872-","T187873-","T187874-","T188117-","T188118-","A188119-","T188120-","C188121-","G188122-","T188123-","C188124-","T188125-","C188126-","C188127-","T188128-","T188129-","A188130-","A188131-","A188132-","G188133-","C188134-","T188135-","T188136-","C188137-","T188138-","G188139-","A188140-","T188141-","G188142-","G188143-","T188144-","A188145-","A188146-","C188147-","T188148-","G188149-","T188150-","G188151-","T188152-","T188153-","A188154-","C188155-","A188156-","T188157-","G188158-","T188159-","G188160-","C188161-","T188162-","C188163-","C188164-","T188165-","A188166-","A188167-","A188168-","A188169-","C188170-","A188171-","A188172-","A188173-","A188174-","T188175-","A188176-","T188177-","G188178-","G188179-","T188180-","C188181-","G188182-","T188183-","G188184-","T188185-","G188186-","T188187-","A188188-","C188189-","G188190-","G188191-","A188192-","A188193-","A188194-","G188195-","A188196-","A188197-","A188198-","G188199-","G188200-","A188201-","G188202-","A188203-","A188204-","A188205-","A188206-","T188207-","G188208-","A188209-","T188210-","A188211-","T188212-","G188213-","G188214-","A188215-","A188216-","T188217-","A188218-","C188219-","C188220-","A188221-","T188222-","T188223-","T188224-","G188225-","T188226-","A188227-","A188228-","G188229-","A188230-","A188231-","A188232-","T188233-","G188234-","T188235-","C188236-","G188237-","G188238-","A188239-","A188240-","G188241-","G188242-","G188243-","T188244-","A188245-","C188246-","T188247-","T188248-","A188249-","T188250-","T188251-","C188252-","A188253-","G188254-","A188255-","T188256-","A188257-","T188258-","T188259-","G188260-","T188261-","A188262-","T188263-","C188264-","T188265-","G188266-","A188267-","C188268-","T188269-","C188270-","T188271-","G188272-","A188273-","T188274-","C188275-","A188276-","A188277-","T188278-","G188279-","T188280-","A188281-","A188282-","A188283-","C188284-","C188285-","T188286-","A188287-","T188288-","G188289-","A188290-","C188291-","A188292-","A188293-","G188294-","A188295-","T188296-","A188297-","A188298-","G188299-","A188300-","C188301-","T188302-","T188303-","A188304-","C188305-","T188306-","C188307-","G188308-","C188309-","A188310-","T188311-","C188312-","T188313-","A188314-","C188315-","T188316-","G188317-","G188318-","A188319-","T188320-","A188321-","G188322-","A188323-","C188324-","A188325-","T188326-","A188327-","A188328-","A188329-","T188330-","A188331-","T188332-","C188333-","C188334-","T188335-","C188336-","C188337-","T188338-","C188339-","G188340-","T188341-","A188342-","A188343-","T188344-","A188345-","A188346-","T188347-","G188348-","A188349-","A188350-","A188351-","T188352-","A188353-","T188354-","A188355-","A188356-","T188357-","A188358-","T188359-","A188360-","C188361-","A188362-","C188363-","T188364-","A188365-","A188366-","T188367-","T188368-","A188369-","T188370-","T188371-","A188372-","A188373-","T188374-","A188375-","T188376-","C188377-","A188378-","A188379-","T188380-","C188381-","G188382-","A188383-","G188384-","T188385-","A188386-","T188387-","T188388-","A188389-","A188390-","C188391-","A188392-","T188393-","A188394-","T188395-","A188396-","A188397-","G188398-","T188399-","T188400-","A188401-","T188402-","T188403-","T188404-","T188405-","T188406-","A188407-","A188408-","A188409-","C188410-","C188411-","C188412-","C188413-","T188414-","T188415-","T188416-","T188417-","G188418-","G188419-","G188420-","T188421-","T188422-","C188423-","C188424-","G188425-","T188426-","C188427-","C188428-","T188429-","A188430-","A188431-","A188432-","C188433-","G188434-","G188435-","C188436-","G188437-","T188438-","T188439-","T188440-","C188441-","G188442-","G188443-","T188444-","C188445-","T188446-","G188447-","T188448-","G188449-","T188450-","C188451-","G188452-","C188453-","C188454-","A188455-","C188456-","C188457-","A188458-","T188459-","G188460-","G188461-","T188462-","C188463-","A188464-","C188465-","A188466-","C188467-","C188468-","G188469-","A188470-","G188471-","C188472-","C188473-","T188474-","C188475-","T188476-","G188477-","C188478-","G188479-","T188480-","G188481-","C188482-","T188483-","C188484-","C188485-","T188486-","C188487-","C188488-","A188489-","T188490-","C188491-","G188492-","A188493-","G188494-","G188495-","A188496-","C188497-","G188498-","A188499-","C188500-","T188501-","T188502-","C188503-","A188504-","A188505-","C188506-","T188507-","A188508-","T188509-","G188510-","A188511-","C188512-","A188513-","G188514-","C188515-","T188516-","C188517-","G188518-","G188519-","T188520-","G188521-","G188522-","C188523-","G188524-","T188525-","C188526-","T188527-","G188528-","C188529-","C188530-","A188531-","G188532-","C188533-","G188534-","T188535-","G188536-","T188537-","A188538-","C188539-","A188540-","T188541-","A188542-","C188543-","G188544-","A188545-","A188546-","T188547-","G188548-","G188549-","C188550-","A188551-","T188552-","T188553-","T188554-","C188555-","T188556-","A188557-","A188558-","G188559-","A188560-","A188561-","A188562-","A188563-","G188564-","T188565-","C188566-","T188567-","A188568-","C188569-","G188570-","G188571-","T188572-","A188573-","T188574-","C188575-","C188576-","T188577-","T188578-","T188579-","C188580-","T188581-","A188582-","C188583-","A188584-","A188585-","T188586-","T188587-","T188588-","C188589-","C188590-","T188591-","T188592-","T188593-","A188594-","A188595-","C188596-","A188597-","A188598-","C188599-","G188600-","G188601-","C188602-","A188603-","A188604-","C188605-","A188606-","G188607-","C188608-","T188609-","G188610-","C188611-","A188612-","G188613-","T188614-","A188615-","T188616-","T188617-","T188618-","T188619-","T188620-","A188621-","T188622-","A188623-","C188624-","T188625-","T188626-","T188627-","G188628-","A188629-","A188630-","T188631-","G188632-","C188633-","A188634-","T188635-","C188636-","G188637-","G188638-","A188639-","C188640-","A188641-","T188642-","T188643-","T188644-","A188645-","T188646-","A188647-","C188648-","A188649-","A188650-","G188651-","G188652-","G188653-","A188654-","G188655-","T188656-","C188657-","C188658-","T188659-","G188660-","T188661-","T188662-","C188663-","T188664-","A188665-","A188666-","T188667-","A188668-","T188669-","T188670-","G188671-","G188672-","C188673-","A188674-","T188675-","C188676-","A188677-","A188678-","T188679-","G188680-","T188681-","T188682-","C188683-","G188684-","G188685-","A188686-","T188687-","C188688-","T188689-","A188690-","T188691-","A188692-","G188693-","G188694-","C188695-","T188696-","T188697-","G188698-","A188699-","T188700-","T188701-","T188702-","T188703-","C188704-","G188705-","C188706-","A188707-","T188708-","T188709-","G188710-","A188711-","C188712-","T188713-","T188714-","T188715-","A188716-","C188717-","A188718-","C188719-","A188720-","G188721-","A188722-","C188723-","A188724-","T188725-","G188726-","A188727-","A188728-","C188729-","A188730-","T188731-","C188732-","C188733-","C188734-","C188735-","T188736-","G188737-","A188738-","A188739-","T188740-","C188741-","T188742-","G188743-","T188744-","A188745-","C188746-","A188747-","T188748-","A188749-","C188750-","T188751-","T188752-","T188753-","G188754-","T188755-","G188756-","G188757-","A188758-","T188759-","T188760-","T188761-","A188762-","C188763-","A188764-","C188765-","T188766-","G188767-","T188768-","T188769-","A188770-","G188771-","A188772-","A188773-","T188774-","C188775-","T188776-","C188777-","T188778-","A188779-","A188780-","C188781-","G188782-","C188783-","T188784-","G188785-","G188786-","C188787-","C188788-","T188789-","C188790-","T188791-","G188792-","T188793-","T188794-","G188795-","T188796-","T188797-","A188798-","C188799-","T188800-","T188801-","T188802-","C188803-","T188804-","A188805-","T188806-","G188807-","A188808-","T188809-","G188810-","C188811-","A188812-","C188813-","G188814-","T188815-","A188816-","T188817-","C188818-","G188819-","T188820-","T188821-","A188822-","T188823-","G188824-","C188825-","A188826-","A188827-","G188828-","C188829-","T188830-","T188831-","T188832-","C188833-","A188834-","T188835-","G188836-","T188837-","T188838-","G188839-","A188840-","C188841-","T188842-","A188843-","C188844-","T188845-","G188846-","C188847-","A188848-","G188849-","T188850-","G188851-","T188852-","T188853-","T188854-","C188855-","T188856-","T188857-","G188858-","C188859-","T188860-","C188861-","T188862-","G188863-","A188864-","C188865-","T188866-","A188867-","C188868-","A188869-","T188870-","A188871-","T188872-","A188873-","C188874-","T188875-","C188876-","T188877-","A188878-","C188879-","A188880-","A188881-","T188882-","C188883-","A188884-","A188885-","A188886-","G188887-","A188888-","A188890-","G188891-","A188892-","T188893-","T188894-","T188895-","C188896-","A188897-","G188898-","T188899-","A188900-","A188901-","A188902-","C188903-","T188904-","T188905-","G188906-","T188907-","A188908-","A188909-","C188910-","A188911-","G188912-","G188913-","A188914-","T188915-","T188916-","G188917-","T188918-","T188919-","T188920-","G188921-","C188922-","T188923-","G188924-","C188925-","T188926-","T188927-","T188928-","C188929-","T188930-","G188931-","G188932-","A188933-","T188934-","T188935-","T188936-","T188937-","A188938-","A188939-","T188940-","T188941-","T188942-","T188943-","G188944-","T188945-","C188946-","A188947-","G188948-","G188949-","A188950-","G188951-","T188952-","C188953-","T188954-","T188955-","G188956-","A188957-","G188958-","G188959-","A188960-","T188961-","A188962-","A188963-","A188964-","G188965-","T188966-","T188967-","T188968-","A188969-","A188970-","A188971-","A188972-","T188973-","A188974-","G188975-","A188976-","A188977-","T188978-","T188979-","A188980-","A188981-","T188982-","A188983-","A188984-","A188985-","G188986-","A188987-","A188988-","C188989-","A188990-","T188991-","A188992-","T188993-","A188994-","G188995-","G188996-","T188997-","C188998-","A188999-","T189000-","T189001-","T189002-","T189003-","T189004-","T189005-","A189006-","A189007-","A189008-","C189009-","A189010-","T189011-","G189012-","G189013-","A189014-","T189015-","A189016-","G189017-","A189018-","A189019-","A189020-","C189021-","C189022-","A189023-","A189024-","G189025-","T190132-","A190133-","T190134-","T190135-","A190136-","A190137-","T190138-","G190139-","G190140-","A190141-","T190142-","A190143-","T190144-","A190145-","T190146-","A190147-","G190148-","A190149-","T190150-","A190151-","A190152-","C190153-","G190154-","C190155-","A190156-","A190157-","T190158-","A190159-","G190160-","G190161-","G190162-","A190163-","C190164-","T190165-","A190166-","A190167-","T190168-","A190169-","G190170-","T190171-","A190172-","T190173-","T190174-","G190175-","T190176-","A190177-","A190178-","A190179-","A190180-","G190181-","A190182-","T190183-","A190184-","T190185-","G190345A"],"OPG071":["R246Q"],"OPG192":["T46-","D47-","D48-","N49-","N50-","E51-","L52-","V53-","L54-","N55-","F56-","K57-","E58-","Y59-","T60-","I61-","S62-","I63-","I64-","T65-","E66-","S67-","C68-","D69-","V70-","G71-","F72-","D73-","S74-","I75-","D76-","I77-","D78-","V79-","I80-","N81-","D82-","Y83-","K84-","I85-","I86-","D87-","M88-","Y89-","T90-"],"OPG195":["T118N","L119-","C120-","I121-","S122-","V123-","Y124-","C125-","D126-","Q127-","E128-","A129-","G130-","D131-","I172-","L210-","K211-","S212-","K213-","A214-","L215-","H216-"]},"labels":{"aa":"OPG071: R246Q; OPG192: T46-, D47-, D48-, N49-, N50-, E51-, L52-, V53-, L54-, N55-, F56-, K57-, E58-, Y59-, T60-, I61-, S62-, I63-, I64-, T65-, E66-, S67-, C68-, D69-, V70-, G71-, F72-, D73-, S74-, I75-, D76-, I77-, D78-, V79-, I80-, N81-, D82-, Y83-, K84-, I85-, I86-, D87-, M88-, Y89-, T90-; OPG195: T118N, L119-, C120-, I121-, S122-, V123-, Y124-, C125-, D126-, Q127-, E128-, A129-, G130-, D131-, I172-, L210-, K211-, S212-, K213-, A214-, L215-, H216-"}}},{"name":"NODE_0000079","node_attrs":{"div":514,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C23353T","C51809T","G69678A","C125492T","C128174T","-188889A"],"OPG039":["D256N"],"OPG071":["R877Q"],"OPG146":["D50N"]},"labels":{"aa":"OPG039: D256N; OPG071: R877Q; OPG146: D50N"}},"children":[{"name":"NODE_0000080","node_attrs":{"div":515,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T27971C","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","-173314A","-173315T","-173316A","-173317T"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}},"children":[{"name":"MK783033","node_attrs":{"div":525,"accession":"MK783033","author":{"author":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J.","value":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J."},"country":{"value":"Nigeria"},"institution":{"value":"CDC, NCEZID/DHCPP/PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"strain":{"value":"MK783033"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-10-09"},"strain_display":{"value":"Nigeria/MK783033/2017-10-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-608T","C25731T","C25768T","C26020T","A56968G","G102267T","C117099T","G129583A","C155707T","G161701A","T187428C"],"OPG042":["D360N"],"OPG074":["L53S"],"OPG121":["G160C"],"OPG136":["R830Q"],"OPG188":["V36I"]},"labels":{"aa":"OPG042: D360N; OPG074: L53S; OPG121: G160C; OPG136: R830Q; OPG188: V36I"}}},{"name":"OP535335","node_attrs":{"div":515,"accession":"OP535335","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"strain":{"value":"MPXV_Nigeria_2017_2947"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-10-XX"},"strain_display":{"value":"Nigeria/OP535335/2017-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000081","node_attrs":{"div":519,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T607-","C92053T","C123000T","C146052T","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","C150831T","C151305T"],"OPG113":["S108L"],"OPG143":["E106K"]},"labels":{"aa":"OPG113: S108L; OPG143: E106K"}},"children":[{"name":"OP612677","node_attrs":{"div":522,"accession":"OP612677","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"strain":{"value":"MPXV/015/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-03-12"},"strain_display":{"value":"Nigeria/OP612677/2019-03-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C56351T","G74032A","T76087-","A89106-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","G190782A"],"OPG016":["E125K"],"OPG074":["E259K"],"OPG094":["A85T"]},"labels":{"aa":"OPG016: E125K; OPG074: E259K; OPG094: A85T"}}},{"name":"NODE_0000082","node_attrs":{"div":548,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C2930T","C18493T","C18908T","G21898A","G23626A","C25254T","C29199T","G36901A","G44085A","G63034A","G75099A","G75144A","G76509A","C87659T","G115332A","C115572T","G122627A","C128771T","C140739T","A149394-","G151519T","G151875A","C160008T","C160312T","G165130A","G168862A","-173314A","-173315T","-173316A","-173317T","G174491A","G176289A","G176366A","C177703T","G194280A","A196614-","A196615-"],"OPG003":["E560K"],"OPG003_dup":["E560K"],"OPG037":["S179L"],"OPG039":["H165Y"],"OPG045":["E22K"],"OPG064":["S605L"],"OPG082":["S140L"],"OPG097":["H123Y"],"OPG109":["E597K"],"OPG133":["R42Q","S122F"],"OPG143":["T230M"],"OPG178":["G4V","D123N"],"OPG205":["A212T","M237I","S683L"]},"labels":{"aa":"OPG003: E560K; OPG003_dup: E560K; OPG037: S179L; OPG039: H165Y; OPG045: E22K; OPG064: S605L; OPG082: S140L; OPG097: H123Y; OPG109: E597K; OPG133: R42Q, S122F; OPG143: T230M; OPG178: G4V, D123N; OPG205: A212T, M237I, S683L"}},"children":[{"name":"OP413718","node_attrs":{"div":548,"accession":"OP413718","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"strain":{"value":"9000360"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP413718/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T133171-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"]}}},{"name":"OP536812","node_attrs":{"div":548,"accession":"OP536812","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"strain":{"value":"9000450"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536812/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000083","node_attrs":{"div":513,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C23564T","C72362T","C83326T","G87230A","G87297A","G91728A","C119296T","C121320T","G125249A","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","G148412A","C164832T","C168120T","T173297-","A173298-","T173299-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-"],"OPG092":["D196N"],"OPG105":["S734L"],"OPG109":["H740Y"],"OPG136":["D98N"],"OPG139":["A17T"],"OPG145":["E435K"],"OPG193":["L263F"]},"labels":{"aa":"OPG092: D196N; OPG105: S734L; OPG109: H740Y; OPG136: D98N; OPG139: A17T; OPG145: E435K; OPG193: L263F","clade":"A.1"}},"children":[{"name":"MT903343","node_attrs":{"div":516,"accession":"MT903343","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"United Kingdom"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-UK_P1"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-09-XX"},"strain_display":{"value":"United Kingdom/MT903343/2018-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-608T","G28838A","G92349A","-173297T","-173298A","-173299T","-173314A","-173315T","-173316A","-173317T","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G188494A","-196616A"],"OPG045":["A142V"],"OPG113":["E207K"]},"labels":{"aa":"OPG045: A142V; OPG113: E207K"}}},{"name":"MN648051","node_attrs":{"div":517,"accession":"MN648051","author":{"author":"Cohen Gihon,I.,Israeli,O.,Shifman,O.,Erez,N.,Melamed,S.,Paran,N.,Beth-Din,A.,Zvi,A.","value":"Cohen Gihon,I.,Israeli,O.,Shifman,O.,Erez,N.,Melamed,S.,Paran,N.,Beth-Din,A.,Zvi,A."},"country":{"value":"Israel"},"institution":{"value":"Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MN648051"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-10-04"},"strain_display":{"value":"Israel/MN648051/2018-10-04"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["T607-","C8772T","C91363T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A147593T","G150568A","-173297T","-173298A","-173299T","G177273A","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A196615-"],"OPG172":["E56V"],"OPG205":["D540N"]},"labels":{"aa":"OPG172: E56V; OPG205: D540N"}}},{"name":"MT903341","node_attrs":{"div":515,"accession":"MT903341","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"Nigeria"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-M5320_M15_Bayelsa"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-08-14"},"strain_display":{"value":"Nigeria/MT903341/2018-08-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-608T","G3153-","A3154-","T3155-","T3156-","C3157-","G3158-","A3159-","A3160-","T3161-","C3162-","T3163-","C3164-","T3165-","T3166-","T3167-","G3168-","A3169-","G3170-","G3171-","A3172-","G3173-","A3174-","C3175-","T3176-","T3177-","A3178-","T3179-","G3180-","T3181-","C3182-","A3183-","C3184-","G3185-","A3186-","C3187-","T3188-","A3189-","C3190-","A3191-","T3192-","T3193-","T3194-","T3195-","T3196-","C3197-","G3198-","A3199-","T3200-","G3201-","A3202-","T3203-","G3204-","G3205-","A3206-","A3207-","T3208-","C3209-","T3210-","A3211-","T3212-","C3213-","T3214-","T3215-","A3216-","T3217-","C3218-","G3219-","A3220-","A3221-","T3222-","G3223-","A3224-","T3225-","A3226-","T3227-","A3228-","T3229-","T3230-","T3231-","T3232-","T3233-","C3234-","A3235-","T3236-","A3237-","A3238-","A3239-","T3240-","A3241-","C3242-","A3243-","C3244-","T3245-","T3246-","T3247-","T3248-","A3249-","T3250-","A3251-","G3252-","T3253-","C3254-","C3255-","T3256-","C3257-","G3258-","T3259-","T3260-","T3261-","A3262-","A3263-","A3264-","C3265-","A3266-","G3267-","A3268-","A3269-","T3270-","T3271-","T3272-","A3273-","G3274-","T3275-","A3276-","T3277-","G3278-","T3279-","A3280-","G3281-","T3282-","T3283-","C3284-","C3285-","G3286-","C3287-","A3288-","A3289-","A3290-","T3291-","G3292-","A3293-","C3294-","T3295-","C3296-","G3297-","T3298-","C3299-","C3300-","C3301-","T3302-","T3303-","A3304-","A3305-","T3306-","A3307-","G3308-","G3309-","C3310-","A3311-","G3312-","T3313-","A3314-","G3315-","G3316-","C3317-","T3318-","A3319-","T3320-","T3321-","A3322-","T3323-","C3324-","T3325-","T3326-","C3327-","T3328-","T3329-","T3330-","A3331-","C3332-","G3333-","T3334-","A3335-","G3336-","T3337-","G3338-","A3339-","T3340-","C3341-","G3342-","T3343-","C3344-","G3345-","T3346-","A3347-","G3348-","G3349-","G3350-","A3351-","G3352-","A3353-","G3354-","A3355-","A3356-","C3357-","T3358-","C3359-","C3360-","G3361-","A3362-","C3363-","A3364-","T3365-","C3366-","T3367-","T3368-","G3369-","T3370-","A3371-","G3372-","A3373-","A3374-","C3375-","A3376-","A3377-","C3378-","G3379-","A3380-","T3381-","T3382-","T3383-","A3384-","A3385-","T3386-","C3387-","A3388-","T3389-","A3390-","G3391-","G3392-","T3393-","A3394-","G3395-","A3396-","G3397-","A3398-","T3399-","A3400-","C3401-","T3402-","T3403-","T3404-","C3405-","A3406-","G3407-","T3408-","C3409-","T3410-","G3411-","T3412-","G3413-","G3414-","T3415-","G3416-","G3417-","A3418-","T3419-","A3420-","A3421-","T3422-","G3423-","T3424-","C3425-","A3426-","T3427-","T3428-","A3429-","A3430-","C3431-","G3432-","A3433-","C3434-","A3435-","T3436-","C3437-","C3438-","G3439-","C3440-","C3441-","T3442-","T3443-","G3444-","T3445-","A3446-","T3447-","A3448-","T3449-","A3450-","A3451-","T3452-","G3453-","T3454-","T3455-","T3456-","C3457-","T3458-","G3459-","T3460-","T3461-","T3462-","T3463-","C3464-","A3465-","A3466-","A3467-","C3468-","A3469-","C3470-","C3471-","A3472-","A3473-","G3474-","T3475-","C3476-","G3477-","A3478-","A3479-","T3480-","A3481-","C3482-","T3483-","G3484-","T3485-","C3486-","T3487-","T3488-","A3489-","T3490-","C3491-","G3492-","T3493-","C3494-","T3495-","T3496-","T3497-","A3498-","G3499-","T3500-","C3501-","G3502-","G3503-","A3504-","A3505-","G3506-","G3507-","T3508-","T3509-","G3510-","A3511-","T3512-","G3513-","T3514-","C3515-","G3516-","T3517-","A3518-","T3519-","C3520-","C3521-","G3522-","A3523-","T3524-","G3525-","T3526-","A3527-","T3528-","A3529-","C3530-","G3531-","A3532-","G3533-","G3534-","T3535-","A3536-","T3537-","G3538-","A3539-","G3540-","G3541-","C3542-","A3543-","A3544-","C3545-","A3546-","T3547-","T3548-","G3549-","T3550-","T3551-","A3552-","T3553-","T3554-","G3555-","C3556-","A3557-","A3558-","T3559-","T3560-","C3561-","T3562-","G3563-","G3564-","A3565-","A3566-","G3567-","G3568-","C3569-","G3570-","G3571-","T3572-","A3573-","T3574-","G3575-","A3576-","A3577-","G3578-","A3579-","G3580-","G3581-","A3582-","G3583-","T3584-","C3585-","A3586-","T3587-","T3588-","G3589-","T3590-","A3591-","T3592-","T3593-","A3594-","T3595-","A3596-","G3597-","T3598-","A3599-","T3600-","T3601-","C3602-","G3603-","T3604-","C3605-","T3606-","T3607-","T3608-","C3609-","T3610-","G3611-","A3612-","A3613-","T3614-","G3615-","T3616-","C3617-","G3618-","A3619-","A3620-","T3621-","C3622-","T3623-","A3624-","T3625-","C3626-","T3627-","A3628-","G3629-","T3630-","A3631-","G3632-","A3633-","T3634-","A3635-","C3636-","C3637-","G3638-","T3639-","A3640-","G3641-","T3642-","A3643-","T3644-","A3645-","T3646-","T3647-","G3648-","A3649-","G3650-","A3651-","G3652-","A3653-","G3654-","C3655-","G3656-","A3657-","C3658-","T3659-","T3660-","C3661-","C3662-","A3663-","T3664-","A3665-","T3666-","C3667-","C3668-","T3669-","T3670-","G3671-","A3672-","T3673-","T3674-","A3675-","T3676-","G3677-","T3678-","T3679-","T3680-","T3681-","A3682-","T3683-","G3684-","A3685-","A3686-","T3687-","A3688-","G3689-","A3690-","T3691-","A3692-","A3693-","A3694-","G3695-","T3696-","A3697-","G3698-","A3699-","T3700-","G3701-","T3702-","T3703-","G3704-","T3705-","C3706-","C3707-","T3708-","T3709-","C3710-","T3711-","T3712-","C3713-","C3714-","T3715-","T3716-","T3717-","T3718-","G3719-","T3720-","A3721-","A3722-","T3723-","T3724-","T3725-","C3726-","C3727-","C3728-","G3729-","T3730-","A3731-","T3732-","T3733-","T3734-","T3735-","T3736-","G3737-","T3738-","T3739-","C3740-","G3741-","T3742-","G3743-","C3744-","C3745-","A3746-","A3747-","T3748-","T3749-","G3750-","A3751-","G3752-","T3753-","A3754-","A3755-","C3756-","A3757-","T3758-","T3759-","A3760-","T3761-","G3762-","A3763-","G3764-","A3765-","A3766-","T3767-","A3768-","T3769-","G3770-","A3771-","C3772-","C3773-","T3774-","G3775-","T3776-","T3777-","G3778-","C3779-","A3780-","C3781-","A3782-","A3783-","T3784-","C3785-","G3786-","T3787-","T3788-","C3789-","T3790-","T3791-","T3792-","A3793-","T3794-","G3795-","T3796-","A3797-","T3798-","T3799-","C3800-","C3801-","A3802-","T3803-","G3804-","A3805-","T3806-","G3807-","G3808-","G3809-","T3810-","G3811-","T3812-","A3813-","C3814-","A3815-","A3816-","T3817-","C3818-","A3819-","A3820-","G3821-","A3822-","T3823-","T3824-","A3825-","T3826-","T3827-","A3828-","C3829-","G3830-","T3831-","A3832-","T3833-","C3834-","C3835-","T3836-","C3837-","G3838-","T3839-","A3840-","T3841-","C3842-","G3843-","G3844-","C3845-","T3846-","C3847-","C3848-","T3849-","C3850-","G3851-","A3852-","G3853-","A3854-","T3855-","A3856-","A3857-","A3858-","A3859-","G3860-","A3861-","G3862-","C3863-","A3864-","T3865-","A3866-","C3867-","A3868-","C3869-","C3870-","A3871-","C3872-","A3873-","C3874-","G3875-","A3876-","G3877-","G3878-","A3879-","C3880-","T3881-","A3882-","T3883-","G3884-","T3885-","T3886-","T3887-","G3888-","G3889-","T3890-","A3891-","T3892-","A3893-","C3894-","T3895-","G3896-","T3897-","T3898-","G3899-","A3900-","A3901-","G3902-","G3903-","T3904-","A3905-","A3906-","G3907-","T3908-","G3909-","T3910-","G3911-","T3912-","A3913-","A3914-","C3915-","G3916-","G3917-","C3918-","G3919-","T3920-","A3921-","T3922-","T3923-","T3924-","C3925-","C3926-","G3927-","A3928-","T3929-","T3930-","T3931-","T3932-","C3933-","G3934-","T3935-","A3936-","A3937-","C3938-","C3939-","G3940-","C3941-","G3942-","T3943-","T3944-","A3945-","A3946-","T3947-","G3948-","T3949-","T3950-","T3951-","G3952-","C3953-","T3954-","C3955-","C3956-","A3957-","T3958-","G3959-","A3960-","T3961-","C3962-","T3963-","A3964-","T3965-","T3966-","A3967-","T3968-","C3969-","G3970-","C3971-","G3972-","T3973-","A3974-","G3975-","A3976-","T3977-","G3978-","A3979-","A3980-","T3981-","C3982-","G3983-","C3984-","T3985-","T3986-","C3987-","T3988-","C3989-","A3990-","G3991-","C3992-","T3993-","C3994-","G3995-","C3996-","A3997-","T3998-","C3999-","T4000-","T4001-","A4002-","G4003-","T4004-","G4005-","T4006-","G4007-","A4008-","C4009-","T4010-","C4011-","T4012-","T4013-","T4014-","G4015-","A4016-","C4017-","T4018-","T4019-","G4020-","T4021-","A4022-","A4023-","T4024-","A4025-","A4026-","T4027-","T4028-","G4029-","C4030-","T4031-","T4032-","T4033-","C4034-","G4035-","T4036-","G4037-","G4038-","A4039-","A4040-","C4041-","G4042-","C4043-","G4044-","G4045-","A4046-","T4047-","A4048-","T4049-","G4050-","T4051-","G4052-","T4053-","T4054-","T4055-","A4056-","C4057-","A4058-","G4059-","T4060-","A4061-","G4062-","T4063-","A4064-","A4065-","T4066-","G4067-","A4068-","A4069-","G4070-","A4071-","G4072-","A4073-","A4074-","G4075-","T4076-","G4077-","A4078-","G4079-","T4080-","C4081-","C4082-","A4083-","T4084-","C4085-","C4086-","T4087-","C4088-","A4089-","T4090-","C4091-","G4092-","A4093-","C4094-","G4095-","C4096-","A4097-","A4098-","T4099-","T4100-","A4101-","G4102-","G4103-","G4104-","T4105-","C4106-","A4107-","G4108-","A4109-","T4110-","C4111-","C4112-","T4113-","T4114-","T4115-","A4116-","G4117-","T4118-","C4119-","A4120-","A4121-","T4122-","A4123-","A4124-","T4125-","T4126-","T4127-","G4128-","T4129-","A4130-","C4131-","A4132-","G4133-","A4134-","A4135-","C4136-","G4137-","T4138-","A4139-","A4140-","T4141-","A4142-","G4143-","T4144-","T4145-","T4146-","A4147-","A4148-","G4149-","C4150-","T4151-","C4152-","C4153-","C4154-","A4155-","T4156-","T4157-","G4158-","A4159-","A4160-","T4161-","T4162-","T4163-","A4164-","T4165-","A4166-","T4167-","C4168-","T4169-","A4170-","A4171-","G4172-","A4173-","T4174-","A4175-","A4176-","C4177-","A4178-","C4179-","A4180-","G4181-","C4182-","A4183-","A4184-","T4185-","A4186-","G4187-","A4188-","T4189-","C4190-","G4191-","G4192-","A4193-","T4194-","G4195-","A4196-","T4197-","T4198-","T4199-","A4200-","C4201-","T4202-","A4203-","A4204-","A4205-","G4206-","T4207-","C4208-","A4209-","T4210-","C4211-","A4212-","A4213-","T4214-","G4215-","G4216-","G4217-","G4218-","T4219-","C4220-","C4221-","G4222-","T4223-","T4224-","A4225-","G4226-","T4227-","A4228-","T4229-","A4230-","T4231-","C4232-","A4233-","A4234-","A4235-","G4236-","A4237-","T4238-","C4239-","T4240-","T4241-","G4242-","T4243-","T4244-","A4245-","T4246-","C4247-","G4248-","A4249-","T4250-","T4251-","G4252-","A4253-","T4254-","A4255-","G4256-","T4257-","G4258-","A4259-","A4260-","T4261-","G4262-","A4263-","A4264-","T4265-","C4266-","A4267-","G4268-","A4269-","T4270-","A4271-","G4272-","T4273-","G4274-","G4275-","T4276-","G4277-","T4278-","A4279-","G4280-","A4281-","G4282-","G4283-","A4284-","A4285-","T4286-","A4287-","T4288-","G4289-","T4290-","C4291-","C4292-","T4293-","T4294-","T4295-","T4296-","T4297-","T4298-","A4299-","T4300-","C4301-","C4302-","T4303-","T4304-","G4305-","C4306-","T4307-","A4308-","T4309-","C4310-","A4311-","A4312-","A4313-","G4314-","T4315-","T4316-","A4317-","C4318-","G4319-","C4320-","A4321-","T4322-","G4323-","C4324-","C4325-","G4326-","T4327-","G4328-","G4329-","C4330-","G4331-","T4332-","A4333-","A4334-","C4335-","A4336-","A4337-","T4338-","A4339-","T4340-","C4341-","T4342-","T4343-","T4344-","A4345-","A4346-","T4347-","A4348-","C4349-","A4350-","G4351-","A4352-","T4353-","G4354-","G4355-","A4356-","T4357-","T4358-","A4359-","A4360-","A4361-","T4362-","C4363-","G4364-","T4365-","G4366-","T4367-","A4368-","T4369-","T4370-","C4371-","A4372-","T4373-","C4374-","G4375-","T4376-","A4377-","T4378-","A4379-","G4380-","C4381-","A4382-","A4383-","T4384-","G4385-","T4386-","A4387-","A4388-","T4389-","G4390-","G4391-","A4392-","G4393-","A4394-","G4395-","T4396-","T4397-","A4398-","C4399-","C4400-","A4401-","C4402-","A4403-","T4404-","T4405-","T4406-","T4407-","A4408-","G4409-","T4410-","C4411-","G4412-","T4413-","T4414-","T4415-","A4416-","T4417-","T4418-","C4419-","A4420-","G4421-","A4422-","T4423-","C4424-","G4425-","C4426-","A4427-","G4428-","T4429-","G4430-","T4431-","T4432-","T4433-","A4434-","A4435-","T4436-","A4437-","A4438-","C4439-","T4440-","A4441-","A4442-","T4443-","T4444-","T4445-","A4446-","A4447-","A4448-","C4449-","A4450-","G4451-","A4452-","T4453-","G4454-","A4455-","G4456-","A4457-","T4458-","G4459-","A4460-","T4461-","A4462-","T4463-","A4464-","T4465-","C4466-","C4467-","A4468-","C4469-","A4470-","T4471-","C4472-","A4473-","A4474-","A4475-","G4476-","A4477-","A4478-","T4479-","G4480-","C4481-","G4482-","A4483-","G4484-","A4485-","T4486-","A4487-","C4488-","A4489-","T4490-","A4491-","T4492-","G4493-","A4494-","C4495-","A4496-","G4497-","A4498-","C4499-","A4500-","T4501-","T4502-","A4503-","T4504-","T4505-","G4506-","A4507-","C4508-","A4509-","G4510-","A4511-","A4512-","A4513-","T4514-","G4515-","T4516-","G4517-","A4518-","C4519-","C4520-","T4521-","T4522-","C4523-","A4524-","T4525-","T4526-","A4527-","T4528-","C4529-","A4530-","C4531-","C4532-","G4533-","T4534-","C4535-","G4536-","T4537-","C4538-","C4539-","A4540-","T4541-","A4542-","A4543-","A4544-","T4545-","G4546-","C4547-","G4548-","T4549-","T4550-","A4551-","G4552-","G4553-","T4554-","A4555-","C4556-","G4557-","T4558-","A4559-","C4560-","C4561-","A4562-","C4563-","A4564-","T4565-","A4566-","C4567-","T4568-","A4569-","T4570-","C4571-","G4572-","T4573-","T4574-","A4575-","A4576-","C4577-","G4578-","A4579-","T4580-","G4581-","C4582-","G4583-","C4584-","A4585-","C4586-","A4587-","A4588-","T4589-","C4590-","T4591-","C4592-","G4593-","T4594-","C4595-","C4596-","A4597-","T4598-","T4599-","T4600-","C4601-","A4602-","T4603-","C4604-","C4605-","A4606-","T4607-","C4608-","T4609-","T4610-","C4611-","A4612-","T4613-","A4614-","A4615-","T4616-","G4617-","A4618-","T4619-","T4620-","T4621-","A4622-","C4623-","T4624-","T4625-","T4626-","T4627-","T4628-","C4629-","A4630-","T4631-","A4632-","A4633-","T4634-","T4635-","A4636-","G4637-","A4638-","G4639-","A4640-","A4641-","A4642-","A4643-","A4644-","G4645-","A4646-","T4647-","C4648-","A4649-","A4650-","G4651-","G4652-","T4653-","A4654-","T4655-","A4656-","A4657-","A4658-","A4659-","A4660-","T4661-","T4662-","A4663-","G4664-","A4665-","A4666-","G4667-","T4668-","G4669-","T4670-","T4671-","A4672-","G4673-","A4674-","C4675-","T4676-","A4677-","T4678-","A4679-","A4680-","A4681-","C4682-","T4683-","A4684-","A4685-","C4686-","T4687-","T4688-","A4689-","T4690-","G4691-","A4692-","C4693-","T4694-","T4695-","A4696-","A4697-","C4698-","T4699-","A4700-","A4701-","C4702-","T4703-","T4704-","A4705-","T4706-","G4707-","A4708-","C4709-","T4710-","T4711-","A4712-","A4713-","C4714-","T4715-","A4716-","A4717-","C4718-","T4719-","T4720-","A4721-","T4722-","G4723-","A4724-","C4725-","T4726-","T4727-","A4728-","A4729-","C4730-","T4731-","A4732-","A4733-","C4734-","T4735-","T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","A4748-","A4749-","C4750-","T4751-","T4752-","A4753-","T4754-","G4755-","A4756-","C4757-","T4758-","T4759-","A4760-","A4761-","C4762-","T4763-","A4764-","A4765-","C4766-","T4767-","T4768-","A4769-","T4770-","G4771-","A4772-","C4773-","T4774-","T4775-","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","A4807-","T4808-","T4809-","A4810-","A4811-","C4812-","T4813-","C4814-","A4815-","T4816-","T4817-","T4818-","C4819-","A4820-","A4821-","G4822-","A4823-","A4824-","A4825-","G4826-","G4827-","T4828-","G4829-","G4830-","G4831-","T4832-","G4833-","G4834-","A4835-","T4836-","A4837-","G4838-","A4839-","A4840-","C4841-","T4842-","C4843-","T4844-","A4845-","T4846-","A4847-","T4848-","G4849-","A4850-","C4851-","A4852-","G4853-","C4854-","T4855-","T4856-","G4857-","T4858-","G4859-","A4860-","A4861-","A4862-","C4863-","A4864-","A4865-","T4866-","T4867-","A4868-","G4869-","A4870-","T4871-","C4872-","C4873-","C4874-","T4875-","A4876-","A4877-","T4878-","T4879-","T4880-","C4881-","T4882-","A4883-","A4884-","T4885-","G4886-","G4887-","A4888-","A4889-","G4890-","T4891-","T4892-","T4893-","T4894-","G4895-","A4896-","T4897-","A4898-","G4899-","G4900-","A4901-","G4902-","A4903-","T4904-","T4905-","G4906-","T4907-","C4908-","A4909-","T4910-","C4911-","A4912-","G4913-","T4914-","T4915-","G4916-","A4917-","T4918-","A4919-","C4920-","A4921-","T4922-","T4923-","G4924-","T4925-","T4926-","T4927-","A4928-","T4929-","T4930-","A4931-","T4932-","C4933-","T4934-","C4935-","A4936-","T4937-","C4938-","T4939-","A4940-","T4941-","T4942-","A4943-","G4944-","A4945-","G4946-","C4947-","A4948-","C4949-","G4950-","T4951-","C4952-","T4953-","G4954-","T4955-","T4956-","T4957-","A4958-","G4959-","A4960-","G4961-","C4962-","T4963-","T4964-","T4965-","A4966-","G4967-","T4968-","G4969-","A4970-","C4971-","C4972-","T4973-","G4974-","C4975-","T4976-","C4977-","G4978-","G4979-","T4980-","T4981-","A4982-","C4983-","T4984-","T4985-","C4986-","T4987-","G4988-","T4989-","G4990-","T4991-","A4992-","A4993-","A4994-","T4995-","C4996-","T4997-","T4998-","G4999-","A5000-","A5001-","T5002-","C5003-","C5004-","T5005-","T5006-","T5007-","A5008-","G5009-","T5010-","G5011-","A5012-","T5013-","A5014-","C5015-","A5016-","C5017-","T5018-","G5019-","T5020-","G5021-","T5022-","C5023-","A5024-","A5025-","A5026-","A5027-","C5028-","T5029-","G5030-","G5031-","A5032-","T5033-","G5034-","T5035-","T5036-","T5037-","A5038-","G5039-","A5040-","A5041-","T5042-","A5043-","C5044-","C5045-","T5046-","A5047-","T5048-","G5049-","T5050-","A5051-","G5052-","A5053-","A5054-","T5055-","A5056-","T5057-","G5058-","G5059-","G5060-","A5061-","A5062-","G5063-","C5064-","A5065-","T5066-","G5067-","C5068-","T5069-","T5070-","G5071-","T5072-","T5073-","T5074-","T5075-","T5076-","G5077-","T5078-","C5079-","T5080-","C5081-","T5082-","A5083-","T5084-","T5085-","A5086-","T5087-","A5088-","G5089-","A5090-","T5091-","T5092-","A5093-","A5094-","C5095-","T5096-","C5097-","A5098-","T5099-","A5100-","C5101-","A5102-","T5103-","G5104-","G5105-","T5106-","T5107-","G5108-","T5109-","A5110-","T5111-","T5112-","A5113-","T5114-","G5115-","A5116-","A5117-","T5118-","T5119-","T5120-","T5121-","C5122-","A5123-","T5124-","C5125-","T5126-","G5127-","C5128-","C5129-","T5130-","A5131-","A5132-","T5133-","G5134-","T5135-","A5136-","C5137-","T5138-","C5139-","C5140-","A5141-","A5142-","T5143-","T5144-","C5145-","T5146-","T5147-","G5148-","T5149-","T5150-","T5151-","A5152-","C5153-","A5154-","A5155-","T5156-","C5157-","A5158-","A5159-","T5160-","T5161-","A5162-","T5163-","A5164-","T5165-","A5166-","A5167-","T5168-","C5169-","A5170-","A5171-","A5172-","G5173-","A5174-","G5175-","T5176-","G5177-","A5178-","T5179-","G5180-","A5181-","T5182-","G5183-","C5184-","A5185-","T5186-","A5187-","C5188-","A5189-","C5190-","A5191-","T5192-","T5193-","A5194-","C5195-","A5196-","A5197-","A5198-","G5199-","T5200-","G5201-","A5202-","A5203-","T5204-","A5205-","A5206-","T5207-","C5208-","T5209-","A5210-","C5211-","C5212-","A5213-","T5214-","C5215-","A5216-","T5217-","A5218-","A5219-","A5220-","A5221-","T5222-","A5223-","C5224-","T5225-","T5226-","G5227-","A5228-","T5229-","A5230-","C5231-","A5232-","G5233-","A5234-","G5235-","C5236-","T5237-","T5238-","T5239-","A5240-","T5241-","C5242-","A5243-","C5244-","A5245-","T5246-","C5247-","A5248-","T5249-","G5250-","G5251-","T5252-","T5253-","T5254-","T5255-","C5256-","A5257-","A5258-","T5259-","T5260-","G5261-","T5262-","A5263-","T5264-","T5265-","A5266-","T5267-","T5268-","A5269-","A5270-","G5271-","T5272-","A5273-","T5274-","A5275-","G5276-","C5277-","T5278-","A5279-","A5280-","T5281-","T5282-","T5283-","T5284-","A5285-","T5286-","A5287-","C5288-","A5289-","G5290-","T5291-","C5292-","A5293-","A5294-","T5295-","A5296-","G5297-","A5298-","C5299-","A5300-","A5301-","T5302-","G5303-","G5304-","T5305-","T5306-","C5307-","T5308-","C5309-","T5310-","A5311-","A5312-","G5313-","C5314-","A5315-","A5316-","T5317-","A5318-","T5319-","T5320-","T5321-","C5322-","T5323-","A5324-","A5325-","T5326-","A5327-","T5328-","T5329-","T5330-","T5331-","A5332-","A5333-","G5334-","A5335-","T5336-","G5337-","T5338-","G5339-","C5340-","T5341-","T5342-","C5343-","C5344-","C5345-","T5346-","A5347-","C5348-","G5349-","G5350-","G5351-","C5352-","G5353-","A5354-","T5355-","G5356-","A5357-","C5358-","A5359-","G5360-","A5361-","T5362-","C5363-","C5364-","C5365-","C5366-","T5367-","A5368-","T5369-","C5370-","C5371-","A5372-","C5373-","G5374-","G5375-","C5376-","C5377-","A5378-","C5379-","G5380-","T5381-","C5382-","A5383-","A5384-","G5385-","A5386-","C5387-","A5388-","T5389-","G5390-","T5391-","A5392-","T5393-","A5394-","T5395-","C5396-","C5397-","A5398-","T5399-","T5400-","A5401-","C5402-","T5403-","C5404-","A5405-","T5406-","T5407-","A5408-","C5409-","T5410-","G5411-","C5412-","G5413-","T5414-","T5415-","G5416-","A5417-","C5418-","A5419-","T5420-","T5421-","T5422-","G5423-","C5424-","T5425-","C5426-","C5427-","A5428-","T5429-","T5430-","T5431-","T5432-","C5433-","T5434-","A5435-","A5436-","T5437-","A5438-","G5439-","C5440-","C5441-","A5442-","T5443-","G5444-","A5445-","T5446-","A5447-","C5448-","T5449-","A5450-","A5451-","A5452-","T5453-","C5454-","T5455-","A5456-","T5457-","A5458-","T5459-","A5460-","A5461-","C5462-","C5463-","T5464-","G5465-","C5466-","A5467-","T5468-","A5469-","G5470-","A5471-","T5472-","A5473-","G5474-","C5475-","G5476-","C5477-","G5478-","A5479-","T5480-","A5481-","A5482-","A5483-","G5484-","C5485-","A5486-","A5487-","G5488-","G5489-","T5490-","C5491-","C5492-","T5493-","T5494-","C5495-","C5496-","A5497-","C5498-","C5499-","A5500-","G5501-","C5502-","A5503-","T5504-","C5505-","T5506-","A5507-","G5508-","T5509-","T5510-","G5511-","A5512-","T5513-","T5514-","G5515-","A5516-","T5517-","A5518-","T5519-","C5520-","T5521-","T5522-","C5523-","A5524-","A5525-","T5526-","A5527-","T5528-","A5529-","T5530-","G5531-","G5532-","G5533-","A5534-","T5535-","A5536-","C5537-","A5538-","A5539-","A5540-","G5541-","C5542-","T5543-","T5544-","A5545-","T5546-","A5547-","A5548-","A5549-","T5550-","T5551-","T5552-","C5553-","T5554-","A5555-","A5556-","T5557-","A5558-","C5559-","T5560-","G5561-","T5562-","G5563-","G5564-","G5565-","T5566-","T5567-","C5568-","A5569-","T5570-","C5571-","T5572-","A5573-","C5574-","A5575-","A5576-","G5577-","G5578-","A5579-","A5580-","T5581-","C5582-","C5583-","C5584-","C5585-","T5586-","A5587-","G5588-","T5589-","A5590-","T5591-","A5592-","C5593-","T5594-","G5595-","A5596-","A5597-","T5598-","T5599-","A5600-","T5601-","T5602-","T5603-","T5604-","A5605-","T5606-","A5607-","T5608-","A5609-","G5610-","A5611-","T5612-","C5613-","T5614-","A5615-","A5616-","T5617-","T5618-","T5619-","A5620-","A5621-","C5622-","A5623-","T5624-","C5625-","A5626-","T5627-","T5628-","T5629-","T5630-","C5631-","A5632-","T5633-","C5634-","T5635-","G5636-","G5637-","G5638-","A5639-","T5640-","A5641-","C5642-","C5643-","A5644-","C5645-","A5646-","A5647-","T5648-","T5649-","C5650-","A5651-","A5652-","A5653-","A5654-","T5655-","A5656-","A5657-","A5658-","C5659-","T5660-","C5661-","A5662-","A5663-","C5664-","A5665-","A5666-","C5667-","A5668-","C5669-","T5670-","A5671-","C5672-","T5673-","T5674-","T5675-","C5676-","C5677-","T5678-","T5679-","T5680-","T5681-","T5682-","A5683-","C5684-","A5685-","T5686-","A5687-","T5688-","T5689-","C5690-","C5691-","C5692-","C5693-","T5694-","A5695-","A5696-","A5697-","A5698-","T5699-","A5700-","G5701-","G5702-","C5703-","A5704-","T5705-","T5706-","C5707-","A5708-","A5709-","G5710-","C5711-","A5712-","T5713-","T5714-","C5715-","T5716-","A5717-","T5718-","T5719-","T5720-","T5721-","A5722-","T5723-","A5724-","T5725-","A5726-","T5727-","T5728-","A5729-","C5730-","A5731-","G5732-","C5733-","C5734-","C5735-","C5736-","A5737-","T5738-","G5739-","A5740-","T5741-","C5742-","T5743-","A5744-","C5745-","C5746-","A5747-","T5748-","A5749-","A5750-","G5751-","A5752-","T5753-","C5754-","A5755-","A5756-","C5757-","A5758-","A5759-","T5760-","G5761-","T5762-","C5763-","T5764-","A5765-","T5766-","T5767-","T5768-","C5769-","T5770-","A5771-","C5772-","A5773-","T5774-","A5775-","T5776-","G5777-","C5778-","A5779-","T5780-","T5781-","A5782-","G5783-","A5784-","T5785-","A5786-","G5787-","A5788-","T5789-","A5790-","G5791-","T5792-","A5793-","A5794-","A5795-","G5796-","T5797-","A5798-","A5799-","G5800-","A5801-","G5802-","A5803-","T5804-","C5805-","T5806-","T5807-","G5808-","C5809-","A5810-","C5811-","A5812-","G5813-","A5814-","A5815-","T5816-","T5817-","A5818-","C5819-","A5820-","A5821-","T5822-","T5823-","C5824-","T5825-","T5826-","A5827-","A5828-","T5829-","A5830-","A5831-","T5832-","T5833-","A5834-","T5835-","A5836-","G5837-","A5838-","G5839-","A5840-","A5841-","A5842-","A5843-","T5844-","A5845-","T5846-","C5847-","T5848-","T5849-","C5850-","C5851-","A5852-","T5853-","A5854-","T5855-","A5856-","A5857-","T5858-","T5859-","C5860-","T5861-","T5862-","T5863-","G5864-","A5865-","C5866-","A5867-","C5868-","T5869-","A5870-","A5871-","T5872-","G5873-","C5874-","A5875-","G5876-","A5877-","T5878-","A5879-","T5880-","A5881-","A5882-","T5883-","A5884-","T5885-","C5886-","T5887-","T5888-","T5889-","A5890-","T5891-","A5892-","T5893-","G5894-","T5895-","A5896-","A5897-","T5898-","A5899-","T5900-","A5901-","T5902-","G5903-","C5904-","A5905-","A5906-","A5907-","C5908-","A5909-","G5910-","T5911-","C5912-","T5913-","A5914-","T5915-","C5916-","T5917-","A5918-","C5919-","T5920-","A5921-","T5922-","A5923-","T5924-","A5925-","C5926-","T5927-","G5928-","A5929-","T5930-","C5931-","A5932-","A5933-","T5934-","A5935-","T5936-","T5937-","A5938-","T5939-","C5940-","T5941-","C5942-","T5943-","A5944-","T5945-","G5946-","A5947-","A5948-","T5949-","C5950-","C5951-","T5952-","A5953-","A5954-","A5955-","A5956-","T5957-","A5958-","A5959-","T5960-","C5961-","A5962-","T5963-","A5964-","C5965-","A5966-","G5967-","A5968-","A5969-","C5970-","A5971-","T5972-","C5973-","T5974-","A5975-","C5976-","A5977-","G5978-","G5979-","A5980-","T5981-","C5982-","A5983-","C5984-","A5985-","A5986-","A5987-","T5988-","T5989-","G5990-","G5991-","T5992-","T5993-","C5994-","A5995-","A5996-","G5997-","G5998-","A5999-","G6000-","A6001-","A6002-","A6003-","T6004-","C6005-","T6006-","A6007-","T6008-","C6009-","A6010-","A6011-","A6012-","T6013-","A6014-","T6015-","T6016-","T6017-","T6018-","C6019-","C6020-","T6021-","G6022-","T6023-","C6024-","A6025-","A6026-","C6027-","A6028-","A6029-","C6030-","T6031-","G6032-","G6033-","T6034-","T6035-","C6036-","T6037-","A6038-","G6039-","A6040-","A6041-","C6042-","A6043-","T6044-","A6045-","A6046-","C6047-","A6048-","G6049-","T6050-","C6051-","A6052-","A6053-","C6054-","A6055-","C6056-","C6057-","T6058-","A6059-","A6060-","T6061-","C6062-","C6063-","A6064-","T6065-","G6066-","T6067-","T6068-","T6069-","T6070-","T6071-","T6072-","A6073-","T6074-","A6075-","A6076-","T6077-","C6078-","A6079-","T6080-","C6081-","T6082-","A6083-","C6084-","C6085-","A6086-","A6087-","A6088-","G6089-","A6090-","T6091-","A6092-","A6093-","T6094-","G6095-","A6096-","C6097-","C6098-","A6099-","A6100-","A6101-","G6102-","A6103-","T6104-","C6105-","G6106-","A6107-","G6108-","G6109-","T6110-","C6111-","G6112-","T6113-","C6114-","G6115-","T6116-","G6117-","A6118-","A6119-","A6120-","C6121-","T6122-","G6123-","C6124-","T6125-","C6126-","A6127-","T6128-","C6129-","G6130-","A6131-","C6132-","A6133-","G6134-","C6135-","C6136-","A6137-","T6138-","G6139-","A6140-","A6141-","A6142-","T6143-","C6144-","T6145-","A6146-","C6147-","C6148-","G6149-","A6150-","C6151-","T6152-","C6153-","C6154-","A6155-","T6156-","G6157-","G6158-","T6159-","G6160-","C6161-","G6162-","A6163-","A6164-","T6165-","C6166-","G6167-","C6168-","A6169-","C6170-","T6171-","G6172-","T6173-","C6174-","T6175-","T6176-","A6177-","T6178-","T6179-","C6180-","G6181-","C6182-","C6183-","A6184-","T6185-","T6186-","G6187-","A6188-","T6189-","T6190-","T6191-","T6192-","C6193-","A6194-","T6195-","T6196-","T6197-","T6198-","T6199-","T6200-","A6201-","T6202-","A6203-","A6204-","T6205-","T6206-","A6207-","T6208-","G6209-","T6210-","A6211-","C6212-","A6213-","T6214-","G6215-","T6216-","T6217-","T6218-","T6219-","C6220-","C6221-","T6222-","T6223-","C6224-","T6225-","A6226-","T6227-","T6228-","C6229-","T6230-","C6231-","A6232-","A6233-","G6234-","A6235-","G6236-","T6237-","C6238-","T6239-","A6240-","C6241-","A6242-","A6243-","A6244-","A6245-","A6246-","T6247-","A6248-","T6249-","A6250-","T6251-","T6252-","T6253-","T6254-","T6255-","T6256-","C6257-","G6258-","A6259-","T6260-","A6261-","T6262-","C6263-","T6264-","A6265-","A6266-","G6267-","T6268-","A6269-","C6270-","T6271-","A6272-","A6273-","G6274-","T6275-","T6276-","T6277-","T6278-","T6279-","T6280-","T6281-","A6282-","C6283-","T6284-","G6285-","T6286-","T6287-","T6288-","T6289-","T6290-","G6291-","T6292-","T6293-","A6294-","C6295-","T6296-","G6297-","T6298-","C6299-","T6300-","T6301-","C6302-","C6303-","A6304-","T6305-","T6306-","C6307-","T6308-","T6309-","C6310-","T6311-","A6312-","A6313-","C6314-","T6315-","A6316-","A6317-","A6318-","G6319-","A6320-","T6321-","C6322-","T6323-","G6324-","A6325-","G6326-","A6327-","T6328-","A6329-","A6330-","A6331-","T6332-","T6333-","A6334-","T6335-","A6336-","C6337-","A6338-","A6339-","T6340-","C6341-","T6342-","T6343-","C6344-","G6345-","C6346-","T6347-","A6348-","T6349-","C6350-","G6351-","A6352-","A6353-","C6354-","C6355-","A6356-","T6357-","T6358-","T6359-","T6360-","T6361-","G6362-","T6363-","A6364-","G6365-","T6366-","C6367-","T6368-","A6369-","A6370-","A6371-","G6372-","C6373-","C6374-","T6375-","G6376-","A6377-","A6378-","G6379-","T6380-","A6381-","A6382-","T6383-","T6384-","A6385-","A6386-","C6387-","C6388-","A6389-","A6390-","C6391-","T6392-","G6393-","T6394-","T6395-","T6396-","T6397-","T6398-","A6399-","T6400-","T6401-","A6402-","G6403-","T6404-","G6405-","G6406-","C6407-","T6408-","T6409-","T6410-","T6411-","T6412-","T6413-","C6414-","G6415-","A6416-","T6417-","C6418-","T6419-","A6420-","T6421-","C6422-","C6423-","T6424-","C6425-","G6426-","T6427-","C6428-","C6429-","T6430-","C6431-","T6432-","C6433-","A6434-","T6435-","C6436-","A6437-","T6438-","C6439-","C6440-","T6441-","T6442-","A6443-","T6444-","A6445-","T6446-","T6447-","A6448-","T6449-","T6450-","A6451-","T6452-","C6453-","A6454-","T6455-","T6456-","A6457-","T6458-","T6459-","A6460-","T6461-","C6462-","A6463-","T6464-","A6465-","G6466-","T6467-","C6468-","T6469-","A6470-","T6471-","T6472-","A6473-","A6474-","A6475-","C6476-","A6477-","C6478-","A6479-","A6480-","A6481-","T6482-","C6483-","A6484-","T6485-","C6486-","T6487-","A6488-","C6489-","G6490-","T6491-","T6492-","T6493-","A6494-","T6495-","A6496-","A6497-","C6498-","A6499-","A6500-","C6501-","A6502-","T6503-","T6504-","C6505-","T6506-","C6507-","A6508-","T6509-","T6510-","A6511-","T6512-","T6513-","A6514-","A6515-","T6516-","T6517-","A6518-","G6519-","T6520-","T6521-","C6522-","T6523-","G6524-","T6525-","A6526-","G6527-","A6528-","A6529-","T6530-","A6531-","T6532-","C6533-","T6534-","T6535-","T6536-","A6537-","A6538-","T6539-","A6540-","A6541-","T6542-","T6543-","T6544-","G6545-","G6546-","C6547-","T6548-","A6549-","T6550-","A6551-","C6552-","A6553-","T6554-","C6555-","T6556-","G6557-","T6558-","T6559-","C6560-","A6561-","A6562-","T6563-","A6564-","C6565-","T6566-","A6567-","T6568-","C6569-","T6570-","A6571-","T6572-","T6573-","G6574-","A6575-","T6576-","G6577-","A6578-","T6579-","T6580-","T6581-","C6582-","T6583-","T6584-","T6585-","T6586-","T6587-","T6588-","A6589-","A6590-","G6591-","A6592-","C6593-","T6594-","T6595-","A6596-","A6597-","A6598-","C6599-","T6600-","A6601-","G6602-","T6603-","T6604-","A6605-","T6606-","G6607-","G6608-","T6609-","A6610-","A6611-","T6612-","G6613-","A6614-","C6615-","G6616-","A6617-","T6618-","G6619-","A6620-","A6621-","A6622-","T6623-","C6624-","G6625-","A6626-","G6627-","T6628-","A6629-","G6630-","T6631-","A6632-","A6633-","C6634-","T6635-","T6636-","C6637-","T6638-","A6639-","A6640-","T6641-","A6642-","A6643-","A6644-","G6645-","A6646-","C6647-","T6648-","T6649-","G6650-","A6651-","T6652-","A6653-","T6654-","C6655-","A6656-","T6657-","T6658-","A6659-","T6660-","C6661-","A6662-","T6663-","A6664-","T6665-","G6666-","T6667-","T6668-","T6669-","G6670-","A6671-","T6672-","C6673-","G6674-","T6675-","C6676-","A6677-","T6678-","A6679-","G6680-","T6681-","T6682-","A6683-","A6684-","T6685-","A6686-","G6687-","T6688-","G6689-","T6690-","G6691-","G6692-","C6693-","T6694-","A6695-","A6696-","A6697-","T6698-","G6699-","G6700-","T6701-","A6702-","C6703-","T6704-","G6705-","T6706-","T6707-","A6708-","A6709-","T6710-","A6711-","A6712-","G6713-","T6714-","T6715-","T6716-","A6717-","T6718-","A6719-","G6720-","A6721-","C6722-","A6723-","A6724-","T6725-","A6726-","T6727-","C6728-","A6729-","T6730-","A6731-","G6732-","T6733-","A6734-","T6735-","T6736-","T6737-","T6738-","C6739-","T6740-","T6741-","T6742-","C6743-","C6744-","A6745-","G6746-","A6747-","A6748-","T6749-","T6750-","A6751-","G6752-","A6753-","T6754-","T6755-","A6756-","T6757-","T6758-","T6759-","T6760-","T6761-","T6762-","T6763-","A6764-","A6765-","A6766-","T6767-","A6768-","C6769-","T6770-","G6771-","A6772-","T6773-","C6774-","C6775-","T6776-","C6777-","A6778-","C6779-","A6780-","A6781-","T6782-","T6783-","C6784-","C6785-","G6786-","T6787-","G6788-","A6789-","T6790-","G6791-","T6792-","A6793-","G6794-","C6795-","A6796-","G6797-","T6798-","A6799-","G6800-","T6801-","T6802-","G6803-","G6804-","T6805-","G6806-","C6807-","A6808-","T6809-","G6810-","G6811-","T6812-","C6813-","T6814-","A6815-","T6816-","A6817-","T6818-","C6819-","G6820-","T6821-","T6822-","A6823-","A6824-","A6825-","A6826-","T6827-","G6828-","T6829-","A6830-","T6831-","C6832-","A6833-","T6834-","A6835-","T6836-","A6837-","T6838-","A6839-","A6840-","T6841-","A6842-","G6843-","T6844-","T6845-","T6846-","T6847-","C6848-","T6849-","G6850-","A6851-","C6852-","G6853-","T6854-","G6855-","G6856-","A6857-","G6858-","T6859-","A6860-","C6861-","A6862-","G6863-","A6864-","A6865-","T6866-","T6867-","T6868-","T6869-","C6870-","G6871-","A6872-","T6873-","T6874-","A6875-","A6876-","T6877-","G6878-","A6879-","G6880-","T6881-","T6882-","C6883-","A6884-","T6885-","G6886-","G6887-","T6888-","A6889-","A6890-","G6891-","G6892-","A6893-","A6894-","G6895-","G6896-","G6897-","C6898-","A6899-","A6900-","A6901-","T6902-","G6903-","C6904-","C6905-","T6906-","G6907-","T6908-","A6909-","T6910-","A6911-","T6912-","A6913-","A6914-","T6915-","A6916-","T6917-","A6918-","C6919-","A6920-","T6921-","A6922-","A6923-","G6924-","T6925-","T6926-","A6927-","A6928-","T6929-","A6930-","G6931-","T6932-","T6933-","T6934-","T6935-","T6936-","T6937-","A6938-","T6939-","C6940-","A6941-","T6942-","A6943-","T6944-","T6945-","T6946-","T6947-","C6948-","T6949-","A6950-","A6951-","T6952-","A6953-","C6954-","C6955-","A6956-","T6957-","A6958-","A6959-","T6960-","A6961-","A6962-","A6963-","A6964-","A6965-","T6966-","T6967-","A6968-","T6969-","C6970-","A6971-","T6972-","T6973-","A6974-","T6975-","T6976-","G6977-","C6978-","G6979-","T6980-","T6981-","T6982-","G6983-","G6984-","T6985-","A6986-","G6987-","T6988-","T6989-","C6990-","T6991-","G6992-","C6993-","C6994-","C6995-","T6996-","A6997-","T6998-","C6999-","A7000-","T7001-","C7002-","T7003-","A7004-","T7005-","A7006-","T7007-","C7008-","A7009-","C7010-","T7011-","G7012-","T7013-","C7014-","A7015-","C7016-","T7017-","C7018-","T7019-","C7020-","G7021-","C7022-","T7023-","C7024-","T7025-","C7026-","A7027-","C7028-","T7029-","A7030-","T7031-","A7032-","T7033-","C7034-","T7035-","T7036-","C7037-","T7038-","A7039-","A7040-","A7041-","A7042-","T7043-","T7044-","A7045-","C7046-","A7047-","A7048-","A7049-","C7050-","A7051-","A7052-","C7053-","T7054-","G7055-","G7056-","A7057-","T7058-","A7059-","T7060-","T7061-","C7062-","G7063-","A7064-","T7065-","A7066-","A7067-","C7068-","A7069-","G7070-","C7071-","A7072-","T7073-","T7074-","T7075-","G7076-","T7077-","G7078-","T7079-","A7080-","G7081-","T7082-","T7083-","T7084-","T7085-","T7086-","G7087-","T7088-","C7089-","T7090-","T7091-","T7092-","T7093-","A7094-","C7095-","A7096-","G7097-","T7098-","A7099-","T7100-","A7101-","T7102-","A7103-","C7104-","G7105-","T7106-","T7107-","A7108-","T7109-","T7110-","G7111-","T7112-","C7113-","A7114-","A7115-","A7116-","A7117-","T7118-","C7119-","T7120-","A7121-","A7122-","A7123-","C7124-","A7125-","A7126-","A7127-","T7128-","A7129-","T7130-","T7131-","A7132-","G7133-","C7134-","A7135-","T7136-","A7137-","A7138-","T7139-","A7140-","C7141-","A7142-","T7143-","C7144-","T7145-","A7146-","T7147-","C7148-","T7149-","A7150-","T7151-","A7152-","A7153-","G7154-","A7155-","T7156-","C7157-","A7158-","G7159-","G7160-","A7161-","T7162-","C7163-","C7164-","A7165-","T7166-","G7167-","T7168-","T7169-","C7170-","G7171-","A7172-","G7173-","C7174-","A7175-","T7176-","A7177-","C7178-","T7179-","A7180-","G7181-","C7182-","C7183-","A7184-","T7185-","G7186-","T7187-","A7188-","T7189-","A7190-","T7191-","T7192-","T7193-","G7194-","T7195-","A7196-","A7197-","C7198-","T7199-","T7200-","C7201-","G7202-","T7203-","C7204-","G7205-","T7206-","A7207-","C7208-","A7209-","G7210-","C7211-","G7212-","T7213-","T7214-","A7215-","G7216-","A7217-","T7218-","C7219-","A7220-","A7221-","T7222-","A7223-","G7224-","A7225-","A7226-","T7227-","A7228-","A7229-","A7230-","C7231-","A7232-","A7233-","T7234-","C7235-","G7236-","T7237-","G7238-","T7239-","G7240-","A7241-","C7242-","G7243-","C7244-","A7245-","A7246-","C7247-","T7248-","T7249-","T7250-","T7251-","T7252-","T7253-","A7254-","C7255-","G7256-","A7257-","T7258-","C7259-","T7260-","A7261-","G7262-","T7263-","T7264-","G7265-","T7266-","A7267-","T7268-","G7269-","A7270-","G7271-","T7272-","T7273-","T7274-","A7275-","T7276-","C7277-","G7278-","T7279-","T7280-","T7281-","A7282-","C7283-","A7284-","T7285-","A7286-","A7287-","G7288-","C7289-","A7290-","A7291-","T7292-","T7293-","A7294-","A7295-","C7296-","G7297-","G7298-","C7299-","T7300-","T7301-","T7302-","A7303-","A7304-","C7305-","A7306-","G7307-","A7308-","T7309-","G7310-","A7311-","T7312-","C7313-","T7314-","G7315-","A7316-","G7317-","T7318-","A7319-","A7320-","T7321-","A7322-","A7323-","T7324-","A7325-","T7326-","A7327-","C7328-","C7329-","T7330-","C7331-","T7332-","G7333-","T7334-","T7335-","A7336-","T7337-","A7338-","C7339-","G7340-","T7341-","T7342-","T7343-","A7344-","A7345-","T7346-","G7347-","T7348-","T7349-","C7350-","A7351-","C7352-","G7353-","G7354-","T7355-","C7356-","T7357-","T7358-","A7359-","G7360-","T7361-","A7362-","T7363-","T7364-","T7365-","T7366-","T7367-","A7368-","G7369-","A7370-","T7371-","A7372-","T7373-","C7374-","A7375-","A7376-","T7377-","T7378-","G7379-","T7380-","G7381-","A7382-","T7383-","T7384-","T7385-","A7386-","C7387-","A7388-","C7389-","C7390-","A7391-","T7392-","A7393-","T7394-","T7395-","C7396-","G7397-","A7398-","C7399-","T7400-","C7401-","C7402-","C7403-","T7404-","T7405-","G7406-","T7407-","G7408-","T7409-","G7410-","T7411-","A7412-","A7413-","C7414-","G7415-","T7416-","T7417-","A7418-","G7419-","A7420-","A7421-","A7422-","T7423-","T7424-","C7425-","T7426-","A7427-","A7428-","A7429-","T7430-","C7431-","T7432-","A7433-","T7434-","A7435-","T7436-","T7437-","A7438-","T7439-","C7440-","T7441-","A7442-","T7443-","T7444-","A7445-","C7446-","A7447-","G7448-","C7449-","G7450-","T7451-","A7452-","A7453-","A7454-","A7455-","C7456-","A7457-","C7458-","A7459-","T7460-","T7461-","C7462-","A7463-","A7464-","T7465-","A7466-","T7467-","T7468-","G7469-","T7470-","A7471-","T7472-","T7473-","G7474-","T7475-","T7476-","A7477-","T7478-","T7479-","T7480-","T7481-","T7482-","A7483-","T7484-","A7485-","T7486-","T7487-","A7488-","T7489-","T7490-","T7491-","A7492-","C7493-","A7494-","C7495-","A7496-","A7497-","T7498-","T7499-","A7500-","A7501-","C7502-","A7503-","A7504-","T7505-","G7506-","T7507-","A7508-","T7509-","T7510-","A7511-","T7512-","T7513-","A7514-","G7515-","T7516-","T7517-","T7518-","A7519-","T7520-","A7521-","T7522-","T7523-","A7524-","C7525-","T7526-","G7527-","A7528-","A7529-","T7530-","T7531-","A7532-","A7533-","T7534-","A7535-","A7536-","T7537-","A7538-","T7539-","A7540-","A7541-","A7542-","A7543-","T7544-","T7545-","C7546-","C7547-","C7548-","A7549-","A7550-","T7551-","C7552-","T7553-","T7554-","G7555-","T7556-","C7557-","A7558-","T7559-","A7560-","A7561-","A7562-","C7563-","A7564-","C7565-","A7566-","A7567-","A7568-","A7569-","T7570-","C7571-","C7572-","A7573-","T7574-","T7575-","A7576-","A7577-","A7578-","A7579-","A7580-","T7581-","G7582-","T7583-","C7584-","G7585-","A7586-","T7587-","A7588-","A7589-","A7590-","A7591-","T7592-","A7593-","T7594-","C7595-","T7596-","G7597-","A7598-","T7599-","G7600-","T7601-","T7602-","G7603-","T7604-","T7605-","G7606-","T7607-","T7608-","C7609-","G7610-","C7611-","T7612-","G7613-","C7614-","T7615-","A7616-","T7617-","G7618-","A7619-","T7620-","A7621-","A7622-","T7623-","C7624-","A7625-","G7626-","A7627-","T7628-","C7629-","A7630-","T7631-","T7632-","A7633-","G7634-","C7635-","C7636-","G7637-","A7638-","T7639-","A7640-","G7641-","T7642-","G7643-","G7644-","T7645-","A7646-","A7647-","T7648-","G7649-","C7650-","T7651-","A7652-","T7653-","C7654-","G7655-","A7656-","A7657-","A7658-","C7659-","A7660-","A7661-","C7662-","A7663-","T7664-","C7665-","G7666-","C7667-","C7668-","A7669-","G7670-","A7671-","A7672-","A7673-","T7674-","T7675-","A7676-","C7677-","A7678-","A7679-","A7680-","C7681-","G7682-","C7683-","T7684-","A7685-","C7686-","A7687-","A7688-","C7689-","A7690-","G7691-","A7692-","T7693-","A7694-","T7695-","T7696-","C7697-","C7698-","A7699-","G7700-","C7701-","T7702-","A7703-","T7704-","C7705-","A7706-","G7707-","A7708-","T7709-","T7710-","A7711-","T7712-","G7713-","T7714-","G7715-","G7716-","T7717-","C7718-","C7719-","A7720-","G7721-","A7722-","G7723-","G7724-","G7725-","A7726-","G7727-","A7728-","T7729-","G7730-","G7731-","A7732-","T7733-","A7734-","T7735-","T7736-","G7737-","T7738-","T7739-","T7740-","A7741-","C7742-","A7743-","C7744-","G7745-","G7746-","T7747-","G7748-","A7749-","C7750-","T7751-","G7752-","T7753-","A7754-","T7755-","C7756-","C7757-","A7758-","C7759-","G7760-","C7761-","T7762-","A7763-","G7764-","A7765-","G7766-","A7767-","T7768-","A7769-","T7770-","C7771-","G7772-","A7773-","C7774-","G7775-","G7776-","T7777-","A7778-","T7779-","G7780-","T7781-","A7782-","T7783-","T7784-","G7785-","T7786-","A7787-","G7788-","A7789-","T7790-","G7791-","C7792-","T7793-","C7794-","T7795-","C7796-","A7797-","T7798-","G7799-","G7800-","T7801-","T7802-","A7803-","T7804-","A7805-","C7806-","A7807-","G7808-","G7809-","T7810-","A7811-","T7812-","T7813-","A7814-","G7815-","A7816-","T7817-","G7818-","T7819-","C7820-","A7821-","G7822-","C7823-","A7824-","T7825-","G7826-","T7827-","A7828-","G7829-","T7830-","A7831-","T7832-","T7833-","A7834-","G7835-","T7836-","A7837-","G7838-","A7839-","C7840-","T7841-","A7842-","T7843-","C7844-","A7845-","A7846-","C7847-","G7848-","T7849-","T7850-","C7851-","A7852-","G7853-","G7854-","A7855-","A7856-","A7857-","A7858-","C7859-","C7860-","A7861-","G7862-","A7863-","C7864-","A7865-","C7866-","T7867-","A7868-","C7869-","A7870-","A7871-","C7872-","A7873-","T7874-","C7875-","A7876-","T7877-","A7878-","T7879-","A7880-","T7881-","C7882-","C7883-","C7884-","A7885-","T7886-","C7887-","T7888-","C7889-","T7890-","A7891-","G7892-","G7893-","T7894-","A7895-","T7896-","T7897-","G7898-","T7899-","G7900-","C7901-","T7902-","T7903-","G7904-","T7905-","A7906-","T7907-","T7908-","A7909-","G7910-","T7911-","A7912-","G7913-","G7914-","C7915-","A7916-","T7917-","T7918-","A7919-","T7920-","T7921-","A7922-","T7923-","T7924-","A7925-","C7926-","G7927-","T7928-","G7929-","T7930-","T7931-","G7932-","T7933-","C7934-","T7935-","A7936-","T7937-","T7938-","A7939-","T7940-","C7941-","T7942-","G7943-","T7944-","T7945-","T7946-","A7947-","T7948-","A7949-","T7950-","G7951-","T7952-","T7953-","C7954-","A7955-","C7956-","T7957-","C7958-","G7959-","A7960-","A7961-","G7962-","A7963-","A7964-","C7965-","T7966-","A7967-","A7968-","A7969-","C7970-","T7971-","A7972-","C7973-","C7974-","T7975-","A7976-","T7977-","A7978-","C7979-","A7980-","A7981-","G7982-","A7983-","T7984-","A7985-","T7986-","G7987-","G7988-","T7989-","T7990-","G7991-","T7992-","G7993-","T7994-","T7995-","A7996-","T7997-","A7998-","T7999-","T8000-","T8001-","T8002-","T8003-","T8004-","A8005-","T8006-","A8007-","A8008-","A8009-","A8010-","T8011-","T8012-","T8013-","T8014-","T8015-","T8016-","T8017-","A8018-","T8019-","G8020-","A8021-","G8022-","T8023-","A8024-","T8025-","T8026-","T8027-","T8028-","T8029-","A8030-","C8031-","A8032-","A8033-","A8034-","A8035-","A8036-","T8037-","G8038-","T8039-","A8040-","T8041-","A8042-","T8043-","G8044-","T8045-","A8046-","T8047-","A8048-","A8049-","A8050-","A8051-","A8052-","A8053-","A8054-","A8055-","T8056-","A8057-","C8058-","T8059-","A8060-","A8061-","G8062-","T8063-","A8064-","T8065-","A8066-","C8067-","G8068-","A8069-","T8070-","G8071-","T8072-","A8073-","T8074-","C8075-","C8076-","T8077-","G8078-","T8079-","A8080-","T8081-","T8082-","A8083-","T8084-","T8085-","T8086-","G8087-","T8088-","A8089-","T8090-","T8091-","T8092-","A8093-","T8094-","C8095-","T8096-","A8097-","A8098-","A8099-","C8100-","A8101-","A8102-","T8103-","A8104-","C8105-","T8106-","T8107-","C8108-","T8109-","G8110-","C8111-","C8112-","T8113-","C8114-","T8115-","A8116-","G8117-","A8118-","T8119-","G8120-","G8121-","G8122-","A8123-","T8124-","A8125-","C8126-","A8127-","A8128-","A8129-","A8130-","A8131-","T8132-","T8133-","T8134-","T8135-","T8136-","T8137-","A8138-","T8139-","T8140-","T8141-","C8142-","A8143-","G8144-","C8145-","A8146-","T8147-","A8148-","T8149-","T8150-","A8151-","A8152-","A8153-","G8154-","T8155-","A8156-","A8157-","A8158-","A8159-","T8160-","C8161-","T8162-","A8163-","G8164-","T8165-","T8166-","A8167-","C8168-","C8169-","T8170-","T8171-","G8172-","A8173-","A8174-","A8175-","A8176-","T8177-","G8178-","A8179-","A8180-","T8181-","A8182-","C8183-","A8184-","G8185-","T8186-","G8187-","G8188-","G8189-","T8190-","G8191-","G8192-","T8193-","T8194-","C8195-","C8196-","G8197-","T8198-","A8199-","T8200-","C8201-","A8202-","C8203-","C8204-","A8205-","G8206-","T8207-","A8208-","A8209-","G8210-","A8211-","A8212-","C8213-","A8214-","T8215-","A8216-","A8217-","T8218-","A8219-","G8220-","T8221-","C8222-","G8223-","A8224-","A8225-","T8226-","A8227-","C8228-","A8229-","G8230-","T8231-","A8232-","T8233-","C8234-","C8235-","G8236-","A8237-","T8238-","T8239-","G8240-","A8241-","G8242-","A8243-","T8244-","T8245-","T8246-","T8247-","G8248-","C8249-","A8250-","T8251-","A8252-","C8253-","A8254-","A8255-","T8256-","A8257-","C8258-","T8259-","A8260-","G8261-","T8262-","C8263-","T8264-","A8265-","G8266-","A8267-","A8268-","A8269-","G8270-","A8271-","A8272-","A8273-","T8274-","T8275-","T8276-","G8277-","T8278-","A8279-","A8280-","T8281-","C8282-","A8283-","T8284-","C8285-","C8286-","T8287-","C8288-","T8289-","G8290-","T8291-","G8292-","A8293-","C8294-","A8295-","G8296-","G8297-","A8298-","G8299-","T8300-","C8301-","C8302-","A8303-","T8304-","A8305-","T8306-","A8307-","T8308-","C8309-","T8310-","G8311-","T8312-","A8313-","T8314-","C8315-","A8316-","T8317-","C8318-","G8319-","T8320-","C8321-","T8322-","A8323-","G8324-","T8325-","T8326-","T8327-","T8328-","T8329-","A8330-","T8331-","C8332-","A8333-","G8334-","T8335-","G8336-","T8337-","C8338-","C8339-","T8340-","A8341-","T8342-","G8343-","C8344-","T8345-","A8346-","T8347-","A8348-","T8349-","T8350-","C8351-","C8352-","T8353-","G8354-","T8355-","T8356-","A8357-","T8358-","C8359-","A8360-","T8361-","C8362-","A8363-","T8364-","T8365-","A8366-","G8367-","T8368-","T8369-","A8370-","A8371-","T8372-","G8373-","A8374-","A8375-","A8376-","A8377-","T8378-","A8379-","A8380-","C8381-","T8382-","C8383-","T8384-","C8385-","G8386-","T8387-","G8388-","C8389-","T8390-","T8391-","C8392-","A8393-","G8394-","A8395-","A8396-","A8397-","A8398-","G8399-","T8400-","C8401-","A8402-","A8403-","A8404-","T8405-","A8406-","T8407-","T8408-","G8409-","T8410-","A8411-","T8412-","C8413-","C8414-","A8415-","T8416-","A8417-","C8418-","A8419-","T8420-","A8421-","T8422-","A8423-","T8424-","C8425-","T8426-","C8427-","C8428-","A8429-","A8430-","A8431-","A8432-","C8433-","T8434-","A8435-","T8436-","C8437-","A8438-","C8439-","T8440-","T8441-","A8442-","T8443-","A8444-","C8445-","G8446-","T8447-","T8448-","T8449-","A8450-","T8451-","C8452-","T8453-","T8454-","T8455-","A8456-","A8457-","C8458-","G8459-","A8460-","A8461-","C8462-","A8463-","T8464-","A8465-","T8466-","A8467-","C8468-","C8469-","T8470-","A8471-","G8472-","A8473-","T8474-","G8475-","G8476-","T8477-","T8478-","A8479-","T8480-","T8481-","T8482-","A8483-","C8484-","T8485-","A8486-","A8487-","C8488-","A8489-","G8490-","A8491-","C8492-","A8493-","T8494-","T8495-","T8496-","T8497-","T8498-","T8499-","C8500-","A8501-","A8502-","G8503-","A8504-","T8505-","C8506-","T8507-","A8508-","T8509-","T8510-","G8511-","A8512-","C8513-","A8514-","A8515-","T8516-","A8517-","A8518-","C8519-","T8520-","C8521-","C8522-","T8523-","A8524-","T8525-","A8526-","G8527-","T8528-","T8529-","T8530-","C8531-","C8532-","A8533-","C8534-","A8535-","T8536-","C8537-","A8538-","A8539-","C8540-","C8541-","A8542-","A8543-","G8544-","T8545-","A8546-","A8547-","T8548-","G8549-","A8550-","T8551-","C8552-","A8553-","T8554-","C8555-","T8556-","A8557-","T8558-","T8559-","G8560-","T8561-","T8562-","A8563-","T8564-","A8565-","T8566-","A8567-","A8568-","C8569-","A8570-","A8571-","T8572-","A8573-","A8574-","C8575-","A8576-","T8577-","A8578-","A8579-","C8580-","T8581-","C8582-","T8583-","T8584-","T8585-","T8586-","C8587-","C8588-","A8589-","T8590-","T8591-","T8592-","T8593-","T8594-","A8595-","T8596-","C8597-","A8598-","G8599-","T8600-","A8601-","T8602-","C8603-","T8604-","A8605-","T8606-","A8607-","T8608-","C8609-","A8610-","A8611-","C8612-","G8613-","T8614-","C8615-","G8616-","T8617-","T8618-","G8619-","T8620-","A8621-","G8622-","T8623-","G8624-","A8625-","A8626-","T8627-","A8628-","G8629-","T8630-","A8631-","G8632-","T8633-","C8634-","A8635-","T8636-","T8637-","G8638-","A8639-","T8640-","C8641-","T8642-","A8643-","T8644-","T8645-","A8646-","T8647-","A8648-","T8649-","G8650-","A8651-","A8652-","A8653-","C8654-","G8655-","G8656-","A8657-","T8658-","A8659-","T8660-","G8661-","T8662-","C8663-","T8664-","A8665-","G8666-","T8667-","T8668-","A8669-","A8670-","T8671-","A8672-","T8673-","T8674-","T8675-","T8676-","C8677-","T8678-","T8679-","T8680-","G8681-","A8682-","T8683-","T8684-","T8685-","A8686-","A8687-","A8688-","G8689-","T8690-","C8691-","T8692-","A8693-","T8694-","A8695-","G8696-","T8697-","C8698-","T8699-","T8700-","T8701-","A8702-","C8703-","A8704-","A8705-","A8706-","C8707-","A8708-","T8709-","A8710-","A8711-","T8712-","A8713-","T8714-","C8715-","C8716-","T8717-","T8718-","A8719-","T8720-","C8721-","C8722-","G8723-","A8724-","C8725-","T8726-","T8727-","T8728-","A8729-","T8730-","A8731-","T8732-","T8733-","T8734-","C8735-","C8736-","T8737-","G8738-","T8739-","A8740-","G8741-","G8742-","G8743-","T8744-","G8745-","G8746-","C8747-","A8748-","T8749-","A8750-","A8751-","T8752-","T8753-","T8754-","T8755-","A8756-","T8757-","T8758-","C8759-","T8760-","G8761-","C8762-","C8763-","T8764-","C8765-","C8766-","A8767-","C8768-","A8769-","A8770-","T8771-","C8772-","A8773-","G8774-","T8775-","G8776-","T8777-","T8778-","T8779-","C8780-","C8781-","A8782-","A8783-","A8784-","T8785-","A8786-","T8787-","A8788-","T8789-","T8790-","A8791-","C8792-","T8793-","A8794-","G8795-","A8796-","C8797-","A8798-","A8799-","T8800-","A8801-","T8802-","T8803-","C8804-","C8805-","A8806-","T8807-","A8808-","T8809-","A8810-","G8811-","T8812-","T8813-","A8814-","T8815-","T8816-","A8817-","G8818-","T8819-","T8820-","A8821-","A8822-","G8823-","G8824-","G8825-","A8826-","C8827-","C8828-","C8829-","A8830-","A8831-","T8832-","T8833-","A8834-","G8835-","A8836-","A8837-","C8838-","A8839-","C8840-","G8841-","T8842-","A8843-","C8844-","G8845-","C8846-","G8847-","C8848-","T8849-","T8850-","A8851-","T8852-","T8853-","C8854-","A8855-","T8856-","C8857-","A8858-","T8859-","T8860-","T8861-","G8862-","G8863-","A8864-","T8865-","C8866-","G8867-","T8868-","A8869-","T8870-","T8871-","T8872-","C8873-","A8874-","T8875-","A8876-","A8877-","A8878-","A8879-","G8880-","T8881-","T8882-","A8883-","T8884-","T8885-","A8886-","T8887-","G8888-","T8889-","T8890-","A8891-","T8892-","A8893-","G8894-","A8895-","T8896-","G8897-","T8898-","C8899-","A8900-","A8901-","C8902-","A8903-","C8904-","A8905-","T8906-","T8907-","C8908-","T8909-","A8910-","C8911-","A8912-","T8913-","T8914-","T8915-","T8916-","T8917-","T8918-","T8919-","A8920-","A8921-","T8922-","T8923-","G8924-","T8925-","C8926-","T8927-","A8928-","T8929-","A8930-","T8931-","A8932-","G8933-","T8934-","A8935-","T8936-","T8937-","T8938-","T8939-","T8940-","C8941-","T8942-","G8943-","A8944-","T8945-","A8946-","T8947-","T8948-","T8949-","T8950-","C8951-","T8952-","A8953-","T8954-","A8955-","A8956-","T8957-","A8958-","T8959-","C8960-","A8961-","G8962-","A8963-","A8964-","T8965-","T8966-","G8967-","T8968-","C8969-","T8970-","T8971-","C8972-","C8973-","A8974-","T8975-","A8976-","G8977-","G8978-","A8979-","A8980-","G8981-","T8982-","T8983-","G8984-","T8985-","A8986-","T8987-","A8988-","C8989-","T8990-","A8991-","T8992-","T8993-","C8994-","G8995-","G8996-","A8997-","A8998-","T8999-","C9000-","A9001-","G9002-","T9003-","T9004-","A9005-","C9006-","A9007-","T9008-","G9009-","T9010-","T9011-","T9012-","A9013-","A9014-","A9015-","T9016-","A9017-","A9018-","T9019-","T9020-","C9021-","T9022-","C9023-","T9024-","G9025-","A9026-","T9027-","G9028-","T9029-","C9030-","A9031-","T9032-","T9033-","C9034-","C9035-","T9036-","T9037-","A9038-","T9039-","A9040-","C9041-","A9042-","A9043-","T9044-","C9045-","A9046-","A9047-","A9048-","T9049-","T9050-","C9051-","A9052-","T9053-","T9054-","A9055-","T9056-","T9057-","A9058-","A9059-","A9060-","C9061-","A9062-","G9063-","T9064-","T9065-","T9066-","A9067-","A9068-","T9069-","A9070-","G9071-","T9072-","C9073-","T9074-","G9075-","T9076-","A9077-","G9078-","A9079-","C9080-","C9081-","T9082-","T9083-","T9084-","A9085-","T9086-","C9087-","G9088-","T9089-","C9090-","G9091-","T9092-","A9093-","C9094-","A9095-","T9096-","A9097-","T9098-","C9099-","C9100-","A9101-","T9102-","T9103-","G9104-","T9105-","C9106-","T9107-","T9108-","A9109-","T9110-","T9111-","A9112-","G9113-","T9114-","T9115-","A9116-","C9117-","G9118-","C9119-","T9120-","T9121-","A9122-","T9123-","T9124-","T9125-","T9126-","T9127-","A9128-","T9129-","G9130-","G9131-","G9132-","T9133-","T9134-","T9135-","T9136-","A9137-","C9138-","G9139-","T9140-","T9141-","G9142-","C9143-","T9144-","T9145-","T9146-","A9147-","T9148-","T9149-","A9150-","T9151-","A9152-","T9153-","T9154-","T9155-","T9156-","A9157-","T9158-","A9159-","A9160-","T9161-","A9162-","A9163-","T9164-","G9165-","A9166-","T9167-","T9168-","G9169-","T9170-","T9171-","T9172-","G9173-","A9174-","C9175-","A9176-","A9177-","T9178-","G9179-","T9180-","C9181-","G9182-","T9183-","A9184-","G9185-","T9186-","A9187-","T9188-","A9189-","G9190-","A9191-","T9192-","A9193-","T9194-","A9195-","T9196-","T9197-","A9198-","T9199-","T9200-","A9201-","G9202-","A9203-","G9204-","G9205-","A9206-","G9207-","G9208-","T9209-","A9210-","T9211-","A9212-","A9213-","T9214-","T9215-","A9216-","T9217-","A9218-","A9219-","A9220-","A9221-","A9222-","G9223-","T9224-","T9225-","T9226-","C9227-","T9228-","G9229-","A9230-","G9231-","T9232-","A9233-","C9234-","G9235-","A9236-","T9237-","G9238-","T9239-","T9240-","A9241-","T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","C9257-","A9258-","T9259-","T9260-","A9261-","A9262-","C9263-","A9264-","T9265-","C9266-","A9267-","T9268-","A9269-","C9270-","A9271-","T9272-","C9273-","A9274-","A9275-","T9276-","T9277-","A9278-","A9279-","C9280-","T9281-","A9282-","C9283-","A9284-","T9285-","T9286-","C9287-","T9288-","T9289-","A9290-","T9291-","A9292-","A9293-","C9294-","A9295-","T9296-","T9297-","G9298-","T9299-","A9300-","A9301-","T9302-","C9303-","A9304-","A9305-","A9306-","A9307-","G9308-","A9309-","A9310-","T9311-","T9312-","G9313-","C9314-","A9315-","A9316-","T9317-","T9318-","T9319-","T9320-","G9321-","A9322-","T9323-","G9324-","T9325-","A9326-","T9327-","A9328-","A9329-","C9330-","A9331-","A9332-","C9333-","T9334-","G9335-","T9336-","C9337-","A9338-","A9339-","T9340-","G9341-","G9342-","A9343-","A9344-","T9345-","T9346-","G9347-","T9348-","A9349-","T9350-","A9351-","T9352-","T9353-","A9354-","C9355-","A9356-","A9357-","A9358-","T9359-","T9360-","A9361-","C9362-","G9363-","G9364-","T9365-","A9366-","T9367-","G9368-","T9369-","T9370-","G9371-","T9372-","A9373-","A9374-","C9375-","A9376-","A9377-","C9378-","A9379-","A9380-","A9381-","T9382-","A9383-","C9384-","C9385-","G9386-","A9387-","T9388-","C9389-","G9390-","G9391-","T9392-","A9393-","A9394-","T9395-","T9396-","G9397-","T9398-","C9399-","T9400-","C9401-","T9402-","G9403-","C9404-","C9405-","G9406-","C9407-","T9408-","G9409-","T9410-","A9411-","A9412-","T9413-","A9414-","G9415-","A9416-","A9417-","T9418-","T9419-","A9420-","A9421-","T9422-","T9423-","A9424-","T9425-","A9426-","T9427-","A9428-","T9429-","C9430-","T9431-","A9432-","T9433-","T9434-","A9435-","C9436-","A9437-","C9438-","C9439-","G9440-","G9441-","C9442-","C9443-","T9444-","T9445-","G9446-","T9447-","A9448-","T9449-","C9450-","A9451-","T9452-","A9453-","A9454-","T9455-","A9456-","A9457-","A9458-","G9459-","T9460-","T9461-","G9462-","T9463-","G9464-","G9465-","T9466-","A9467-","G9468-","T9469-","A9470-","T9471-","G9472-","A9473-","T9474-","C9475-","T9476-","C9477-","C9478-","A9479-","T9480-","A9481-","T9482-","T9483-","T9484-","A9485-","T9486-","A9487-","A9488-","T9489-","T9490-","T9491-","A9492-","G9493-","T9494-","A9495-","C9496-","T9497-","T9498-","T9499-","G9500-","T9501-","A9502-","T9503-","T9504-","T9505-","A9506-","G9507-","T9508-","T9509-","T9510-","T9511-","T9512-","T9513-","T9514-","G9515-","G9516-","A9517-","A9518-","T9519-","C9520-","A9521-","T9522-","A9523-","A9524-","A9525-","A9526-","A9527-","A9528-","A9529-","G9530-","T9531-","T9532-","T9533-","T9534-","A9535-","C9536-","T9537-","A9538-","A9539-","T9540-","T9541-","T9542-","A9543-","A9544-","A9545-","A9546-","T9547-","T9548-","T9549-","A9550-","A9551-","A9552-","A9553-","A9554-","G9555-","T9556-","A9557-","T9558-","T9559-","T9560-","A9561-","C9562-","A9563-","T9564-","T9565-","T9566-","T9567-","T9568-","C9569-","A9570-","C9571-","T9572-","G9573-","T9574-","T9575-","T9576-","A9577-","G9578-","T9579-","C9580-","G9581-","C9582-","G9583-","G9584-","A9585-","T9586-","A9587-","T9588-","G9589-","G9590-","A9591-","A9592-","T9593-","T9594-","C9595-","G9596-","A9597-","T9598-","C9599-","C9600-","T9601-","G9602-","T9603-","C9604-","A9605-","A9606-","A9607-","A9608-","T9609-","C9610-","A9611-","A9612-","T9613-","A9614-","C9615-","A9616-","T9617-","C9618-","A9619-","T9620-","C9621-","T9622-","A9623-","T9624-","A9625-","G9626-","A9627-","T9628-","C9629-","A9630-","T9631-","G9632-","T9633-","A9634-","A9635-","C9636-","A9637-","A9638-","T9639-","A9640-","T9641-","T9642-","A9643-","C9644-","A9645-","A9646-","T9647-","A9648-","C9649-","A9650-","T9651-","A9652-","G9653-","A9654-","T9655-","G9656-","A9657-","A9658-","C9659-","C9660-","A9661-","A9662-","A9663-","T9664-","G9665-","A9666-","T9667-","A9668-","T9669-","A9670-","A9671-","G9672-","A9673-","C9674-","T9675-","A9676-","A9677-","C9678-","A9679-","G9680-","T9681-","A9682-","T9683-","G9684-","C9685-","A9686-","T9687-","T9688-","A9689-","T9690-","C9691-","C9692-","G9693-","A9694-","A9695-","A9696-","T9697-","G9698-","T9699-","T9700-","A9701-","A9702-","T9703-","A9704-","A9705-","C9706-","A9707-","T9708-","T9709-","A9710-","C9711-","A9712-","T9713-","A9714-","T9715-","T9716-","A9717-","T9718-","A9719-","T9720-","C9721-","A9722-","A9723-","T9724-","A9725-","T9726-","C9727-","A9728-","C9729-","A9730-","A9731-","A9732-","A9733-","A9734-","T9735-","A9736-","A9737-","A9738-","T9739-","C9740-","C9741-","A9742-","C9743-","A9744-","T9745-","T9746-","T9747-","G9748-","G9749-","C9750-","T9751-","A9752-","A9753-","T9754-","C9755-","G9756-","A9757-","T9758-","T9759-","T9760-","C9761-","G9762-","G9763-","G9764-","C9765-","T9766-","T9767-","G9768-","G9769-","A9770-","A9771-","A9772-","A9773-","A9774-","A9775-","C9776-","G9777-","T9778-","A9779-","T9780-","C9781-","G9782-","C9783-","C9784-","G9785-","G9786-","A9787-","A9788-","G9789-","G9790-","G9791-","A9792-","C9793-","T9794-","A9795-","T9796-","A9797-","T9798-","G9799-","A9800-","C9801-","T9802-","A9803-","A9804-","C9805-","T9806-","T9807-","A9808-","T9809-","C9810-","T9811-","A9812-","G9813-","A9814-","G9815-","A9816-","T9817-","A9818-","C9819-","A9820-","G9821-","G9822-","A9823-","A9824-","T9825-","A9826-","C9827-","A9828-","A9829-","C9830-","A9831-","A9832-","T9833-","C9834-","A9835-","A9836-","A9837-","A9838-","C9839-","T9840-","T9841-","A9842-","C9843-","T9844-","G9845-","A9846-","A9847-","A9848-","C9849-","T9850-","A9851-","T9852-","A9853-","C9854-","G9855-","T9856-","A9857-","A9858-","C9859-","T9860-","G9861-","T9862-","C9863-","A9864-","A9865-","A9866-","A9867-","A9868-","A9869-","A9870-","T9871-","A9872-","A9873-","A9874-","A9875-","A9876-","C9877-","A9878-","T9879-","A9880-","T9881-","A9882-","T9883-","G9884-","G9885-","T9886-","C9887-","T9888-","A9889-","T9890-","A9891-","T9892-","A9893-","T9894-","A9895-","C9896-","A9897-","C9898-","T9899-","A9900-","C9901-","A9902-","A9903-","T9904-","T9905-","T9906-","A9907-","G9908-","T9909-","T9910-","A9911-","T9912-","T9913-","A9914-","A9915-","T9916-","G9917-","T9918-","G9919-","G9920-","T9921-","T9922-","A9923-","T9924-","T9925-","G9926-","A9927-","T9928-","T9929-","G9930-","G9931-","A9932-","T9933-","A9934-","A9935-","C9936-","C9937-","G9938-","A9939-","T9940-","G9941-","T9942-","G9943-","A9944-","T9945-","T9946-","G9947-","T9948-","T9949-","C9950-","A9951-","A9952-","T9953-","C9954-","A9955-","A9956-","T9957-","A9958-","T9959-","T9960-","A9961-","A9962-","G9963-","A9964-","G9965-","G9966-","G9967-","T9968-","T9969-","G9970-","G9971-","T9972-","A9973-","A9974-","A9975-","T9976-","T9977-","G9978-","G9979-","T9980-","A9981-","C9982-","A9983-","T9984-","A9985-","G9986-","C9987-","T9988-","A9989-","A9990-","T9991-","A9992-","A9993-","T9994-","A9995-","C9996-","A9997-","T9998-","A9999-","T10000-","A10001-","C10002-","T10003-","C10004-","C10005-","A10006-","A10007-","A10008-","T10009-","A10010-","C10011-","A10012-","C10013-","C10014-","C10015-","A10016-","A10017-","T10018-","A10019-","A10020-","T10021-","A10022-","C10023-","T10024-","A10025-","C10026-","A10027-","A10028-","C10029-","C10030-","A10031-","T10032-","T10033-","T10034-","C10035-","T10036-","G10037-","A10038-","G10039-","T10040-","T10041-","G10042-","G10043-","A10044-","T10045-","A10046-","T10047-","C10048-","A10049-","T10050-","C10051-","A10052-","A10053-","A10054-","A10055-","T10056-","A10057-","C10058-","T10059-","G10060-","G10061-","A10062-","T10063-","A10064-","A10065-","A10066-","T10067-","A10068-","C10069-","G10070-","A10071-","G10072-","G10073-","A10074-","C10075-","A10076-","T10077-","G10078-","T10079-","A10080-","T10081-","A10082-","G10083-","A10084-","G10085-","T10086-","A10087-","A10088-","G10089-","T10090-","A10091-","A10092-","A10093-","G10094-","A10095-","A10096-","A10097-","A10098-","A10099-","G10100-","A10101-","A10102-","T10103-","G10104-","T10105-","G10106-","G10107-","A10108-","A10109-","T10110-","T10111-","T10112-","G10113-","C10114-","T10115-","A10116-","T10117-","G10118-","A10119-","A10120-","G10121-","T10122-","T10123-","G10124-","T10125-","T10126-","T10127-","A10128-","C10129-","T10130-","C10131-","A10132-","A10133-","A10134-","A10135-","C10136-","G10137-","A10138-","T10139-","T10140-","A10141-","G10142-","A10143-","A10144-","A10145-","A10146-","C10147-","G10148-","A10149-","T10150-","A10151-","G10152-","A10153-","T10154-","A10155-","C10156-","T10157-","T10158-","T10159-","G10160-","G10161-","T10162-","T10163-","T10164-","A10165-","T10166-","T10167-","G10168-","G10169-","A10170-","T10171-","T10172-","C10173-","G10174-","T10175-","G10176-","T10177-","A10178-","A10179-","T10180-","C10181-","A10182-","T10183-","A10184-","T10185-","A10186-","T10187-","T10188-","T10189-","T10190-","G10191-","C10192-","A10193-","T10194-","A10195-","A10196-","C10197-","A10198-","T10199-","G10200-","T10201-","A10202-","T10203-","C10204-","A10205-","A10206-","T10207-","A10208-","T10209-","A10210-","T10211-","G10212-","G10213-","C10214-","A10215-","T10216-","A10217-","G10218-","A10219-","A10220-","C10221-","A10222-","C10223-","G10224-","A10225-","A10226-","G10227-","A10228-","G10229-","A10230-","A10231-","A10232-","C10233-","C10234-","G10235-","G10236-","T10237-","G10238-","C10239-","G10240-","T10241-","C10242-","A10243-","G10244-","A10245-","T10246-","A10247-","A10248-","T10249-","T10250-","G10251-","T10252-","C10253-","C10254-","T10255-","A10256-","T10257-","A10258-","T10259-","G10260-","C10261-","C10262-","G10263-","T10264-","A10265-","C10266-","A10267-","C10268-","G10269-","T10270-","T10271-","T10272-","T10273-","A10274-","A10275-","A10276-","A10277-","A10278-","A10279-","A10280-","T10281-","A10282-","A10283-","C10284-","A10285-","A10286-","T10287-","G10288-","A10289-","G10290-","C10291-","A10292-","A10293-","G10294-","T10295-","T10296-","C10297-","T10298-","A10299-","T10300-","A10301-","A10302-","G10303-","C10304-","T10305-","A10306-","G10307-","T10308-","T10309-","A10310-","A10311-","C10312-","T10313-","A10314-","A10315-","T10316-","A10317-","A10318-","A10319-","T10320-","A10321-","A10322-","A10323-","A10324-","A10325-","G10326-","T10327-","T10328-","T10329-","A10330-","A10331-","T10332-","T10333-","A10334-","T10335-","C10336-","G10337-","A10338-","C10339-","G10340-","A10341-","T10342-","A10343-","T10344-","A10345-","T10346-","G10347-","T10348-","C10349-","G10350-","T10351-","T10352-","A10353-","T10354-","T10355-","T10356-","T10357-","T10358-","C10359-","T10360-","C10361-","T10362-","C10363-","A10364-","T10365-","A10366-","T10367-","G10368-","A10369-","A10370-","A10371-","G10372-","A10373-","T10374-","T10375-","A10376-","A10377-","T10378-","T10379-","T10380-","G10381-","A10382-","T10383-","T10384-","C10385-","T10386-","A10387-","A10388-","T10389-","A10390-","T10391-","A10392-","A10393-","T10394-","C10395-","T10396-","T10397-","C10398-","A10399-","G10400-","T10401-","A10402-","T10403-","T10404-","G10405-","G10406-","A10407-","T10408-","G10409-","A10410-","A10411-","T10412-","C10413-","T10414-","C10415-","A10416-","A10417-","T10418-","T10419-","C10420-","A10421-","A10422-","A10423-","T10424-","T10425-","A10426-","A10427-","T10428-","T10429-","C10430-","C10431-","A10432-","T10433-","T10434-","A10435-","G10436-","A10437-","T10438-","T10439-","A10440-","G10441-","A10442-","T10443-","T10444-","A10445-","G10446-","A10447-","T10448-","T10449-","A10450-","G10451-","A10452-","T10453-","C10454-","A10455-","T10456-","A10457-","A10458-","A10459-","T10460-","A10461-","A10462-","A10463-","A10464-","A10465-","T10466-","A10467-","G10468-","T10469-","A10470-","G10471-","C10472-","A10473-","C10474-","G10475-","C10476-","A10477-","C10478-","T10479-","A10480-","C10481-","T10482-","T10483-","C10484-","A10485-","G10486-","C10487-","C10488-","A10489-","A10490-","A10491-","T10492-","A10493-","T10494-","T10495-","C10496-","T10497-","T10498-","T10499-","T10500-","T10501-","T10502-","G10503-","A10504-","A10505-","A10506-","C10507-","G10508-","C10509-","C10510-","A10511-","T10512-","C10513-","T10514-","A10515-","G10516-","C10517-","G10518-","T10519-","A10520-","A10521-","T10522-","G10523-","A10524-","G10525-","A10526-","A10527-","C10528-","A10529-","C10530-","A10531-","A10532-","G10533-","T10534-","G10535-","A10536-","A10537-","C10538-","C10539-","T10540-","A10541-","T10542-","A10543-","A10544-","T10545-","G10546-","A10547-","G10548-","C10549-","A10550-","A10551-","A10552-","T10553-","T10554-","T10555-","A10556-","T10557-","T10558-","A10559-","G10560-","T10561-","A10562-","T10563-","C10564-","G10565-","G10566-","T10567-","T10568-","A10569-","C10570-","A10571-","T10572-","G10573-","A10574-","A10575-","G10576-","G10577-","A10578-","C10579-","T10580-","T10581-","T10582-","A10583-","C10584-","G10585-","T10586-","A10587-","G10588-","A10589-","G10590-","T10591-","G10592-","G10593-","T10594-","G10595-","A10596-","T10597-","T10598-","C10599-","C10600-","T10601-","C10602-","C10603-","A10604-","T10605-","C10606-","T10607-","G10608-","T10609-","G10610-","G10611-","T10612-","A10613-","C10614-","G10615-","A10616-","A10617-","C10618-","G10619-","G10620-","T10621-","T10622-","T10623-","C10624-","A10625-","T10626-","C10627-","T10628-","T10629-","C10630-","T10631-","T10632-","T10633-","G10634-","A10635-","T10636-","G10637-","C10638-","C10639-","A10640-","C10641-","C10642-","A10643-","C10644-","C10645-","C10646-","A10647-","G10648-","A10649-","T10650-","G10651-","T10652-","T10653-","C10654-","T10655-","A10656-","T10657-","A10658-","A10659-","A10660-","C10661-","T10662-","T10663-","G10664-","G10665-","T10666-","A10667-","T10668-","C10669-","C10670-","T10671-","C10672-","G10673-","T10674-","C10675-","C10676-","G10677-","A10678-","T10679-","T10680-","T10681-","C10682-","A10683-","T10684-","A10685-","T10686-","C10687-","A10688-","T10689-","T10690-","T10691-","G10692-","C10693-","C10694-","A10695-","A10696-","C10697-","C10698-","A10699-","A10700-","T10701-","A10702-","C10703-","A10704-","T10705-","A10706-","T10707-","A10708-","G10709-","C10710-","T10711-","A10712-","A10713-","A10714-","C10715-","C10716-","C10717-","A10718-","G10719-","G10720-","C10721-","A10722-","T10723-","A10724-","C10725-","G10726-","T10727-","T10728-","C10729-","C10730-","A10731-","C10732-","A10733-","C10734-","A10735-","T10736-","C10737-","C10738-","G10739-","G10740-","A10741-","A10742-","C10743-","A10744-","A10745-","T10746-","G10747-","A10748-","A10749-","A10750-","T10751-","T10752-","C10753-","T10754-","C10755-","C10756-","A10757-","G10758-","A10759-","A10760-","G10761-","A10762-","T10763-","G10764-","T10765-","T10766-","A10767-","C10768-","A10769-","A10770-","T10771-","G10772-","G10773-","C10774-","T10775-","A10776-","G10777-","A10778-","T10779-","T10780-","T10781-","G10782-","G10783-","A10784-","C10785-","A10786-","T10787-","T10788-","T10789-","G10790-","G10791-","T10792-","T10793-","T10794-","C10795-","A10796-","A10797-","C10798-","C10799-","G10800-","C10801-","G10802-","T10803-","T10804-","A10805-","A10806-","C10807-","A10808-","T10809-","A10810-","T10811-","G10812-","A10813-","G10814-","T10815-","G10816-","A10817-","A10818-","C10819-","A10820-","C10821-","A10822-","C10823-","C10824-","C10825-","A10826-","T10827-","A10828-","C10829-","A10830-","T10831-","G10832-","A10833-","A10834-","A10835-","G10836-","C10837-","G10838-","A10839-","T10840-","G10841-","A10842-","G10843-","A10844-","A10845-","A10846-","T10847-","A10848-","G10849-","G10850-","A10851-","T10852-","T10853-","C10854-","T10855-","C10856-","A10857-","T10858-","C10859-","T10860-","T10861-","G10862-","C10863-","C10864-","A10865-","A10866-","A10867-","A10868-","T10869-","A10870-","T10871-","C10872-","A10873-","C10874-","T10875-","A10876-","T10877-","A10878-","A10879-","A10880-","A10881-","A10882-","A10883-","T10884-","T10885-","T10886-","A10887-","T10888-","T10889-","T10890-","A10891-","T10892-","C10893-","A10894-","A10895-","T10896-","T10897-","T10898-","T10899-","A10900-","A10901-","A10902-","G10903-","G10904-","T10905-","A10906-","T10907-","A10908-","A10909-","A10910-","A10911-","A10912-","A10913-","A10914-","T10915-","A10916-","C10917-","T10918-","T10919-","A10920-","T10921-","T10922-","G10923-","T10924-","T10925-","G10926-","C10927-","T10928-","C10929-","G10930-","A10931-","A10932-","T10933-","A10934-","T10935-","T10936-","T10937-","T10938-","G10939-","T10940-","A10941-","T10942-","T10943-","T10944-","G10945-","A10946-","T10947-","G10948-","G10949-","T10950-","A10951-","T10952-","A10953-","C10954-","G10955-","G10956-","A10957-","A10958-","G10959-","A10960-","T10961-","T10962-","A10963-","G10964-","A10965-","A10966-","A10967-","T10968-","G10969-","T10970-","A10971-","G10972-","G10973-","T10974-","A10975-","T10976-","T10977-","A10978-","T10979-","C10980-","A10981-","T10982-","C10983-","A10984-","A10985-","C10986-","T10987-","G10988-","A10989-","T10990-","T10991-","T10992-","T10993-","A10994-","T10995-","G10996-","A10997-","T10998-","G10999-","G11000-","T11001-","T11002-","T11003-","T11004-","A11005-","T11006-","G11007-","A11008-","A11009-","T11010-","T11011-","T11012-","T11013-","A11014-","T11015-","T11016-","A11017-","T11018-","G11019-","C11020-","T11021-","T11022-","C11023-","A11024-","C11025-","T11026-","A11027-","T11028-","T11029-","G11030-","C11031-","A11032-","T11033-","C11034-","G11035-","G11036-","A11037-","A11038-","A11039-","T11040-","A11041-","A11042-","T11043-","A11044-","T11045-","C11046-","A11047-","T11048-","A11049-","T11050-","G11051-","C11052-","T11053-","T11054-","C11055-","C11056-","A11057-","C11058-","G11059-","T11060-","A11061-","T11062-","A11063-","T11064-","T11065-","T11066-","T11067-","A11068-","T11069-","T11070-","T11071-","T11072-","G11073-","T11074-","T11075-","T11076-","T11077-","G11078-","A11079-","C11080-","T11081-","C11082-","A11083-","T11084-","A11085-","A11086-","T11087-","A11088-","C11089-","G11090-","C11091-","A11092-","C11093-","G11094-","T11095-","A11096-","A11097-","T11098-","T11099-","C11100-","T11101-","G11102-","G11103-","A11104-","T11105-","T11106-","A11107-","T11108-","T11109-","G11110-","G11111-","C11112-","A11113-","T11114-","A11115-","T11116-","C11117-","G11118-","A11119-","T11120-","G11121-","A11122-","A11123-","T11124-","A11125-","A11126-","T11127-","T11128-","T11129-","T11130-","A11131-","G11132-","C11133-","T11134-","C11135-","C11136-","A11137-","T11138-","G11139-","C11140-","T11141-","C11142-","A11143-","G11144-","T11145-","A11146-","A11147-","A11148-","T11149-","A11150-","T11151-","T11152-","A11153-","A11154-","T11155-","G11156-","A11157-","G11158-","A11159-","A11160-","C11161-","A11162-","T11163-","A11164-","G11165-","T11166-","G11167-","T11168-","T11169-","G11170-","C11171-","C11172-","T11173-","C11174-","C11175-","T11176-","A11177-","C11178-","C11179-","A11180-","T11181-","T11182-","A11183-","T11184-","T11185-","T11186-","T11187-","T11188-","T11189-","T11190-","C11191-","A11192-","T11193-","C11194-","T11195-","C11196-","A11197-","T11198-","T11199-","C11200-","A11201-","A11202-","T11203-","T11204-","C11205-","T11206-","T11207-","G11208-","A11209-","T11210-","T11211-","G11212-","C11213-","A11214-","G11215-","A11216-","G11217-","A11218-","T11219-","C11220-","T11221-","A11222-","T11223-","A11224-","T11225-","A11226-","A11227-","T11228-","C11229-","A11230-","T11231-","T11232-","A11233-","T11234-","A11235-","G11236-","C11237-","G11238-","T11239-","T11240-","G11241-","A11242-","C11243-","T11244-","T11245-","A11246-","T11247-","G11248-","G11249-","A11250-","C11251-","T11252-","C11253-","T11254-","G11255-","G11256-","A11257-","A11258-","T11259-","C11260-","T11261-","T11262-","A11263-","G11264-","A11265-","C11266-","G11267-","A11268-","T11269-","G11270-","T11271-","A11272-","C11273-","A11274-","G11275-","T11276-","C11277-","A11278-","T11279-","C11280-","T11281-","A11282-","T11283-","A11284-","A11285-","T11286-","C11287-","A11288-","T11289-","G11290-","G11291-","T11292-","A11293-","T11294-","A11295-","T11296-","T11297-","T11298-","A11299-","A11300-","T11301-","A11302-","C11303-","A11304-","T11305-","T11306-","G11307-","T11308-","T11309-","T11310-","T11311-","A11312-","T11313-","A11314-","G11315-","C11316-","A11317-","T11318-","A11319-","G11320-","G11321-","C11322-","A11323-","T11324-","T11325-","A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","C11727T","C39139T","-173297T","-173298A","-173299T","-173314A","-173315T","-173316A","-173317T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A185259-","G185260-","A185261-","A185262-","T185263-","G185264-","T185265-","T185266-","T185267-","G185268-","C185269-","C185270-","A185271-","C185272-","A185273-","T185274-","T185275-","G185276-","G185277-","C185278-","T185279-","A185280-","G185281-","A185282-","G185283-","G185284-","A185285-","A185286-","T185287-","G185288-","C185289-","C185290-","G185291-","T185292-","T185293-","T185294-","A185295-","G185296-","A185297-","T185298-","C185299-","A185300-","A185301-","C185302-","G185303-","T185304-","A185305-","T185306-","T185307-","G185308-","C185309-","G185310-","A185311-","T185312-","A185313-","A185314-","C185315-","A185316-","G185317-","A185318-","C185319-","G185320-","A185321-","C185322-","G185323-","A185324-","T185325-","C185326-","A185327-","G185328-","G185329-","T185330-","T185331-","G185332-","T185333-","T185334-","A185335-","T185336-","T185337-","A185338-","T185339-","G185340-","C185341-","A185342-","G185343-","G185344-","A185345-","A185346-","T185347-","A185348-","C185349-","C185350-","A185351-","T185352-","T185353-","T185354-","C185355-","A185356-","T185357-","G185358-","A185359-","A185360-","G185361-","A185362-","T185363-","A185364-","G185365-","T185366-","G185367-","T185368-","A185369-","G185370-","A185371-","A185372-","A185373-","C185374-","A185375-","G185376-","A185377-","T185378-","A185379-","T185380-","A185381-","C185382-","A185383-","T185384-","T185385-","A185386-","T185387-","G185388-","G185389-","A185390-","C185391-","C185392-","A185393-","G185394-","A185395-","A185396-","A185397-","T185398-","A185399-","A185400-","T185401-","G185402-","T185403-","T185404-","A185405-","A185406-","A185407-","G185408-","G185409-","A185410-","A185411-","A185412-","C185413-","A185414-","T185415-","A185416-","T185417-","G185418-","A185419-","C185420-","A185421-","T185422-","A185423-","A185424-","A185425-","C185426-","A185427-","G185428-","T185429-","A185430-","T185431-","T185432-","G185433-","A185434-","C185435-","C185436-","C185437-","A185438-","C185439-","G185440-","A185441-","G185442-","T185443-","T185444-","A185445-","T185446-","A185447-","A185448-","C185449-","A185450-","A185451-","A185452-","G185453-","T185454-","C185455-","A185456-","A185457-","A185458-","G185459-","A185460-","C185461-","C185462-","C185463-","A185464-","T185465-","T185466-","T185467-","T185468-","C185469-","C185470-","T185471-","G185472-","C185473-","T185474-","C185475-","C185476-","A185477-","T185478-","T185479-","G185480-","A185481-","G185482-","T185483-","G185484-","T185485-","A185486-","A185487-","A185488-","A185489-","T185490-","T185491-","C185492-","A185493-","T185494-","G185495-","G185496-","T185497-","T185498-","G185499-","A185500-","C185501-","A185502-","A185503-","T185504-","T185505-","T185506-","A185507-","G185508-","G185509-","A185510-","A185511-","A185512-","T185513-","G185514-","G185515-","A185516-","T185517-","A185518-","T185519-","G185520-","A185521-","C185522-","A185523-","A185524-","C185525-","C185526-","C185527-","T185528-","A185529-","A185530-","T185531-","T185532-","C185533-","A185534-","T185535-","T185536-","T185537-","T185538-","G185539-","G185540-","G185541-","A185542-","A185543-","G185544-","A185545-","T185546-","G185547-","C185548-","T185549-","A185550-","A185551-","A185552-","A185553-","C185554-","T185555-","A185556-","A185557-","G185558-","A185559-","A185560-","A185561-","C185562-","G185563-","G185564-","A185565-","C185566-","A185567-","T185568-","A185569-","T185570-","A185571-","G185572-","T185573-","G185574-","C185575-","A185576-","A185577-","T185578-","G185579-","A185580-","C185581-","G185582-","A185583-","T185584-","A185585-","A185586-","A185587-","A185588-","G185589-","T185590-","C185591-","C185592-","T185593-","A185594-","C185595-","C185596-","A185597-","T185598-","G185599-","T185600-","A185601-","C185602-","A185603-","G185604-","T185605-","G185606-","A185607-","G185608-","A185609-","A185610-","A185611-","T185612-","A185613-","A185614-","A185615-","A185616-","A185617-","T185618-","A185619-","T185620-","A185621-","G185622-","A185623-","C185624-","T185625-","T185626-","T185627-","G185628-","G185629-","A185630-","T185631-","A185632-","T185633-","A185634-","A185635-","C185636-","T185637-","A185638-","T185639-","G185640-","G185641-","A185642-","G185643-","A185644-","T185645-","A185646-","T185647-","T185648-","A185649-","T185650-","T185651-","T185652-","C185653-","T185654-","A185655-","A185656-","T185657-","A185658-","T185659-","G185660-","G185661-","T185662-","T185663-","T185664-","A185665-","T185666-","C185667-","T185668-","A185669-","C185670-","A185671-","A185672-","T185673-","C185674-","T185675-","A185676-","C185677-","T185678-","A185679-","G185680-","T185681-","C185682-","A185683-","G185684-","G185685-","A185686-","T185687-","T185688-","A185689-","T185690-","G185691-","G185692-","A185693-","G185694-","A185695-","T185696-","G185697-","G185698-","T185699-","A185700-","C185701-","C185702-","A185703-","A185704-","A185705-","T185706-","A185707-","T185708-","A185709-","C185710-","A185711-","T185712-","T185713-","T185714-","A185715-","A185716-","A185717-","T185718-","C185719-","C185720-","G185721-","T185722-","A185723-","A185724-","C185725-","T185726-","A185727-","G185728-","A185729-","T185730-","C185731-","A185732-","G185733-","A185734-","T185735-","C185736-","A185737-","T185738-","G185739-","A185740-","G185741-","T185742-","G185743-","T185744-","G185745-","A185746-","A185747-","T185748-","C185749-","T185750-","A185751-","G185752-","C185753-","T185754-","T185755-","A185756-","G185757-","A185758-","T185759-","C185760-","T185761-","A185762-","A185763-","C185764-","G185765-","T185766-","C185767-","T185768-","A185769-","A185770-","G185771-","G185772-","A185773-","A185774-","G185775-","T185776-","A185777-","A185778-","C185779-","T185780-","G185781-","T185782-","G185783-","A185784-","C185785-","A185786-","T185787-","G185788-","T185789-","C185790-","C185791-","T185792-","G185793-","C185794-","G185795-","T185796-","T185797-","T185798-","A185799-","G185800-","T185801-","A185802-","T185803-","A185804-","C185805-","C185806-","A185807-","A185808-","G185809-","A185810-","A185811-","A185812-","T185813-","A185814-","T185815-","A185816-","T185817-","C185818-","A185819-","A185820-","C185821-","A185822-","T185823-","A185824-","T185825-","G185826-","A185827-","A185828-","G185829-","G185830-","T185831-","C185832-","T185833-","A185834-","T185835-","G185836-","C185837-","T185838-","T185839-","T185840-","A185841-","G185842-","T185843-","G185844-","T185845-","T185846-","A185847-","C185848-","T185849-","A185850-","C185851-","A185852-","T185853-","C185854-","T185855-","A185856-","A185857-","A185858-","G185859-","A185860-","T185861-","C185862-","A185863-","T185864-","T185865-","G185866-","T185867-","G185868-","C185869-","T185870-","A185871-","C185872-","A185873-","G185874-","G185875-","T185876-","A185877-","T185878-","T185879-","G185880-","G185881-","T185882-","T185883-","G185884-","G185885-","T185886-","T185887-","A185888-","A185889-","A185890-","A185891-","T185892-","C185893-","T185894-","A185895-","G185896-","T185897-","G185898-","G185899-","T185900-","T185901-","A185902-","T185903-","G185904-","G185905-","G185906-","A185907-","A185908-","G185909-","G185910-","A185911-","A185912-","G185913-","A185914-","T185915-","G185916-","C185917-","T185918-","G185919-","A185920-","T185921-","A185922-","A185923-","A185924-","C185925-","C185926-","A185927-","C185928-","G185929-","T185930-","G185931-","C185932-","T185933-","T185934-","G185935-","T185936-","T185937-","T185938-","T185939-","C185940-","A185941-","T185942-","C185943-","A185944-","T185945-","T185946-","G185947-","G185948-","A185949-","A185950-","T185951-","T185952-","A185953-","T185954-","T185955-","A185956-","C185957-","A185958-","C185959-","A185960-","C185961-","T185962-","G185963-","T185964-","C185965-","G185966-","T185967-","T185968-","G185969-","G185970-","A185971-","T185972-","T185973-","A185974-","T185975-","T185976-","A185977-","C185978-","T185979-","G185980-","T185981-","T185982-","C185983-","A185984-","T185985-","A185986-","C185987-","G185988-","A185989-","A185990-","G185991-","A185992-","T185993-","A185994-","T185995-","T185996-","T185997-","G185998-","G185999-","A186000-","G186001-","A186002-","A186003-","G186004-","C186005-","A186006-","C186007-","C186008-","T186009-","G186010-","G186011-","C186012-","C186013-","T186014-","G186015-","A186016-","C186017-","T186018-","A186019-","T186020-","G186021-","A186022-","T186023-","C186024-","C186025-","A186026-","T186027-","G186028-","T186029-","A186030-","A186031-","G186032-","T186033-","C186034-","A186035-","T186036-","A186037-","T186038-","A186039-","T186040-","C186041-","C186042-","A186043-","T186044-","A186045-","T186046-","A186047-","G186048-","A186049-","G186050-","T186051-","A186052-","T186053-","A186054-","G186055-","A186056-","G186057-","A186058-","T186059-","A186060-","C186061-","A186062-","T186063-","G186064-","G186065-","A186066-","T186067-","A186068-","G186069-","A186070-","A186071-","T186072-","C186073-","T186074-","A186075-","A186076-","T186077-","G186078-","T186079-","G186080-","T186081-","T186082-","A186083-","C186084-","A186085-","G186086-","C186087-","A186088-","A186089-","C186090-","C186091-","T186092-","C186093-","C186094-","T186095-","T186096-","A186097-","C186098-","A186099-","C186100-","A186101-","T186102-","T186103-","C186104-","G186105-","A186106-","A186107-","T186108-","T186109-","C186110-","A186111-","T186112-","T186113-","C186114-","A186115-","T186116-","G186117-","A186118-","C186119-","A186120-","A186121-","T186122-","T186123-","C186124-","T186125-","A186126-","A186127-","C186128-","G186129-","A186130-","A186131-","T186132-","A186133-","T186134-","G186135-","T186136-","G186137-","G186138-","A186139-","T186140-","A186141-","A186142-","A186143-","G186144-","A186145-","A186146-","A186147-","T186148-","T186149-","A186150-","G186151-","T186152-","A186153-","A186154-","C186155-","A186156-","A186157-","A186158-","T186159-","T186160-","A186161-","A186162-","A186163-","T186164-","G186165-","A186166-","T186167-","C186168-","T186169-","G186170-","T186171-","A186172-","C186173-","A186174-","A186175-","T186176-","G186177-","A186178-","A186179-","T186180-","A186181-","C186182-","A186183-","A186184-","G186185-","A186186-","A186187-","G186188-","A186189-","T186190-","T186191-","A186192-","T186193-","G186194-","G186195-","A186196-","A186197-","T186198-","A186199-","T186200-","A186201-","G186202-","C186203-","G186204-","A186205-","C186206-","G186207-","G186208-","A186209-","T186210-","C186211-","A186212-","T186213-","T186214-","G186215-","C186216-","C186217-","G186218-","G186219-","C186220-","G186221-","T186222-","C186223-","T186224-","A186225-","T186226-","A186227-","A186228-","A186229-","C186230-","A186231-","G186232-","A186233-","T186234-","T186235-","A186236-","G186237-","C186238-","A186239-","A186240-","A186241-","G186242-","G186243-","C186244-","A186245-","T186246-","T186247-","G186248-","A186249-","C186250-","T186251-","T186252-","C186253-","A186254-","G186255-","A186256-","G186257-","G186258-","G186259-","T186260-","A186261-","G186262-","A186263-","G186264-","A186265-","A186266-","A186267-","T186268-","A186269-","G186270-","C186271-","A186272-","A186273-","G186274-","T186275-","G186276-","T186277-","T186278-","A186279-","A186280-","T186281-","A186282-","T186283-","A186284-","G186285-","A186286-","T186287-","G186288-","G186289-","T186290-","A186291-","A186292-","T186293-","C186294-","T186295-","G186296-","T186297-","T186298-","A186299-","G186300-","A186301-","T186302-","A186303-","T186304-","C186305-","G186306-","C186307-","A186308-","T186309-","A186310-","T186311-","C186312-","A186313-","A186314-","G186315-","C186316-","A186317-","G186318-","A186319-","T186320-","A186321-","A186322-","G186323-","G186324-","A186325-","A186326-","A186327-","A186328-","G186329-","A186330-","T186331-","G186332-","G186333-","C186334-","C186335-","G186336-","A186337-","C186338-","A186339-","T186340-","A186341-","C186342-","A186343-","G186344-","A186345-","C186346-","A186347-","A186348-","G186349-","A186350-","A186351-","T186352-","A186353-","A186354-","A186355-","T186356-","G186357-","A186358-","T186359-","A186360-","T186361-","T186362-","A186363-","T186364-","T186365-","A186366-","G186367-","A186368-","G186369-","A186370-","T186371-","T186372-","T186373-","G186374-","T186375-","T186376-","T186377-","A186378-","T186379-","A186380-","C186381-","A186382-","C186383-","A186384-","C186385-","T186386-","C186387-","T186388-","A186389-","T186390-","C186391-","A186392-","G186393-","A186394-","C186395-","A186396-","A186397-","A186398-","G186399-","A186400-","T186401-","A186402-","T186403-","A186404-","A186405-","A186406-","A186407-","G186408-","A186409-","C186410-","A186411-","T186412-","T186413-","A186414-","T186415-","A186416-","G186417-","A186418-","A186419-","T186420-","C186421-","C186422-","G186423-","A186424-","A186425-","G186426-","A186427-","A186428-","G186429-","G186430-","T186431-","A186432-","A186433-","G186434-","A186435-","G186436-","A186437-","T186438-","G186439-","T186440-","T186441-","G186442-","T186443-","A186444-","T186445-","A186446-","A186447-","T186448-","A186449-","G186450-","A186451-","T186452-","G186453-","T186454-","T186455-","A186456-","A186457-","G186458-","A186459-","A186460-","C186461-","A186462-","A186463-","T186464-","C186465-","T186466-","T186467-","G186468-","T186469-","T186470-","A186471-","A186472-","A186473-","A186474-","A186475-","G186476-","T186477-","A186478-","C186479-","T186480-","A186481-","T186482-","T186483-","C186484-","T186485-","A186486-","T186487-","T186488-","G186489-","A186490-","T186491-","A186492-","A186493-","T186494-","T186495-","A186496-","T186497-","C186498-","T186499-","A186500-","T186501-","G186502-","T186503-","G186504-","A186505-","T186506-","A186507-","C186508-","T186509-","T186510-","T186511-","A186512-","G186513-","A186514-","T186515-","G186516-","A186517-","T186518-","T186519-","A186520-","T186521-","A186522-","T186523-","A186524-","T186525-","A186526-","C186527-","A186528-","C186529-","C186530-","T186531-","C186532-","T186533-","G186534-","T186535-","A186536-","G186537-","A186538-","A186539-","T186540-","A186541-","T186542-","A186543-","A186544-","C186545-","A186546-","A186547-","A186548-","T186549-","C186550-","C186551-","T186552-","A186553-","T186554-","G186555-","T186556-","G186557-","T186558-","T186559-","A186560-","G186561-","T186562-","A186563-","A186564-","A186565-","C186566-","G186567-","A186568-","T186569-","A186570-","C186571-","T186572-","T186573-","A186574-","T186575-","A186576-","T186577-","G186578-","A186579-","G186580-","C186581-","T186582-","A186583-","T186584-","G186585-","A186586-","C186587-","T186588-","A186589-","T186590-","C186591-","T186592-","T186593-","G186594-","A186595-","A186596-","T186597-","C186598-","A186599-","T186600-","C186601-","A186602-","G186603-","G186604-","T186605-","G186606-","T186607-","A186608-","G186609-","T186610-","T186611-","G186612-","T186613-","T186614-","C186615-","T186616-","A186617-","T186618-","C186619-","A186620-","T186621-","G186622-","T186623-","T186624-","A186625-","T186626-","G186627-","A186628-","A186629-","A186630-","T186631-","G186632-","A186633-","C186634-","T186635-","A186636-","T186637-","A186638-","A186639-","T186640-","C186641-","T186642-","C186643-","C186644-","T186645-","T186646-","G186647-","G186648-","A186649-","T186650-","A186651-","C186652-","A186653-","A186654-","A186655-","A186656-","G186657-","A186658-","C186659-","G186660-","C186661-","C186662-","A186663-","A186664-","A186665-","G186666-","A186667-","T186668-","G186669-","C186670-","T186671-","A186672-","T186673-","A186674-","G186675-","A186676-","A186677-","G186678-","A186679-","T186680-","G186681-","T186682-","G186683-","A186684-","T186685-","A186686-","G186687-","T186688-","A186689-","G186690-","C186691-","A186692-","A186693-","G186694-","T186695-","G186696-","C186697-","G186698-","G186699-","T186700-","A186701-","G186702-","C186703-","C186704-","G186705-","A186706-","A186707-","G186708-","C186709-","A186710-","T186711-","T186712-","G186713-","A186714-","A186715-","T186716-","G186717-","A186718-","C186719-","A186720-","T186721-","G186722-","T186723-","T186724-","T186725-","A186726-","A186727-","G186728-","G186729-","A186730-","A186731-","T186732-","T186733-","T186734-","G186735-","A186736-","T186737-","A186738-","A186739-","A186740-","A186741-","A186742-","C186743-","G186744-","T186745-","A186746-","A186747-","G186748-","T186749-","G186750-","C186751-","T186752-","A186753-","T186754-","T186755-","A186756-","T186757-","A186758-","A186759-","T186760-","A186761-","A186762-","A186763-","A186764-","G186765-","A186766-","A186767-","G186768-","A186769-","A186770-","G186771-","A186772-","T186773-","A186774-","A186775-","T186776-","T186777-","A186778-","T186779-","C186780-","T186781-","A186782-","A186783-","A186784-","C186785-","A186786-","G186787-","T186788-","T186789-","C186790-","G186791-","C186792-","C186793-","C186794-","G186795-","A186796-","T186797-","A186798-","T186799-","C186800-","T186801-","A186802-","C186803-","C186804-","A186805-","T186806-","A186807-","T186808-","A186809-","A186810-","T186811-","A186812-","T186813-","A186814-","T186815-","A186816-","T186817-","C186818-","A186819-","T186820-","A186821-","G186822-","G186823-","T186824-","G186825-","G186826-","C186827-","A186828-","C186829-","T186830-","A186831-","T186832-","T186833-","C186834-","T186835-","G186836-","C186837-","T186838-","A186839-","C186840-","T186841-","G186842-","T186843-","T186844-","A186845-","G186846-","T186847-","C186848-","A186849-","T186850-","T186851-","A186852-","T186853-","T186854-","T186855-","T186856-","A186857-","A186858-","T186859-","A186860-","T186861-","T186862-","G186863-","G186864-","C186865-","A186866-","A186867-","T186868-","T186869-","T186870-","A186871-","T186872-","A186873-","T186874-","A186875-","G186876-","C186877-","G186878-","C186879-","G186880-","C186881-","A186882-","A186883-","T186884-","A186885-","A186886-","A186887-","T186888-","A186889-","C186890-","A186891-","G186892-","A186893-","A186894-","C186895-","C186896-","A186897-","G186898-","G186899-","A186900-","A186901-","A186902-","T186903-","A186904-","T186905-","G186906-","A186907-","A186908-","A186909-","T186910-","A186911-","A186912-","T186913-","G186914-","A186915-","A186916-","A186917-","T186918-","A186919-","T186920-","G186921-","A186922-","C186923-","A186924-","A186925-","T186926-","A186927-","T186928-","G186929-","A186930-","G186931-","C186932-","A186933-","T186934-","T186935-","A186936-","A186937-","A186938-","T186939-","C186940-","T186941-","G186942-","A186943-","G186944-","C186945-","A186946-","T186947-","C186948-","A186949-","T186950-","G186951-","A186952-","T186953-","A186954-","G186955-","T186956-","C186957-","T186958-","T186959-","G186960-","A186961-","A186962-","A186963-","C186964-","A186965-","G186966-","T186967-","G186968-","T186969-","C186970-","T186971-","A186972-","T186973-","G186974-","G186975-","A186976-","A186977-","A186978-","T186979-","T186980-","A186981-","T186982-","T186983-","G186984-","A186985-","T186986-","A186987-","A186988-","T186989-","C186990-","G186991-","G186992-","T186993-","A186994-","C186995-","T186996-","A186997-","A186998-","T186999-","A187000-","A187001-","A187002-","A187003-","T187004-","A187005-","G187006-","T187007-","T187008-","T187009-","A187010-","A187011-","C187012-","T187013-","C187014-","T187015-","T187016-","T187017-","T187018-","A187019-","G187020-","A187021-","A187022-","C187023-","C187024-","A187025-","G187026-","T187027-","T187028-","T187029-","G187030-","G187031-","T187032-","A187033-","C187034-","T187035-","G187036-","T187037-","A187038-","A187039-","T187040-","T187041-","T187042-","C187043-","A187044-","G187045-","T187046-","T187047-","C187048-","A187049-","T187050-","T187051-","A187052-","C187053-","T187054-","C187055-","G187056-","T187057-","T187058-","G187059-","A187060-","G187061-","A187062-","A187063-","T187064-","A187065-","T187066-","T187067-","G187068-","A187069-","T187070-","G187071-","A187072-","T187073-","T187074-","T187075-","T187076-","T187077-","T187078-","T187079-","T187080-","A187081-","A187082-","A187083-","T187084-","G187085-","A187086-","G187087-","T187088-","A187089-","T187090-","C187091-","G187092-","G187093-","T187094-","A187095-","G187096-","T187097-","T187098-","A187099-","C187100-","A187101-","T187102-","A187103-","T187104-","T187105-","A187106-","C187107-","C187108-","A187109-","T187110-","A187111-","T187112-","C187113-","A187114-","T187115-","C187116-","C187117-","A187118-","T187119-","T187120-","A187121-","T187122-","A187123-","T187124-","A187125-","A187126-","T187127-","C187128-","G187129-","A187130-","T187131-","G187132-","A187133-","T187134-","G187135-","C187136-","A187137-","T187138-","G187139-","T187140-","A187141-","T187142-","T187143-","A187144-","G187145-","A187146-","A187147-","T187148-","A187149-","C187150-","T187151-","T187152-","T187153-","C187154-","C187155-","G187156-","A187157-","A187158-","T187159-","A187160-","A187161-","G187162-","T187163-","C187164-","T187165-","T187166-","C187167-","T187168-","A187169-","A187170-","A187171-","T187172-","A187173-","T187174-","T187175-","G187176-","T187177-","A187178-","T187179-","T187180-","A187181-","A187182-","T187183-","T187184-","A187185-","T187186-","G187187-","A187188-","A187189-","A187190-","A187191-","A187192-","C187193-","T187194-","A187195-","T187196-","G187197-","C187198-","T187199-","A187200-","T187201-","G187202-","T187203-","G187204-","A187205-","G187206-","T187207-","A187208-","T187209-","G187210-","A187211-","T187212-","T187213-","C187214-","A187215-","A187216-","A187217-","G187218-","A187219-","T187220-","G187221-","T187222-","T187223-","T187224-","A187225-","A187226-","T187227-","G187228-","A187229-","T187230-","A187231-","C187232-","G187233-","A187234-","T187235-","A187236-","C187237-","T187238-","A187239-","G187240-","A187241-","T187242-","T187243-","T187244-","T187245-","A187246-","T187247-","C187248-","T187249-","C187250-","T187251-","A187252-","G187253-","C187254-","G187255-","A187256-","G187257-","A187258-","T187259-","T187260-","G187261-","T187262-","T187263-","T187264-","A187265-","G187266-","A187267-","A187268-","T187269-","C187270-","A187271-","T187272-","T187273-","T187274-","A187275-","T187276-","C187277-","A187278-","T187279-","A187280-","A187281-","C187282-","T187283-","A187284-","T187285-","G187286-","T187287-","T187288-","T187289-","A187290-","A187291-","T187292-","A187293-","A187294-","A187295-","T187296-","T187297-","C187298-","A187299-","T187300-","C187301-","A187302-","A187303-","C187304-","G187305-","A187306-","A187307-","T187308-","A187309-","T187310-","C187311-","G187312-","A187313-","T187314-","A187315-","A187316-","A187317-","G187318-","A187319-","C187320-","C187321-","T187322-","C187323-","T187324-","T187325-","G187326-","T187327-","A187328-","A187329-","T187330-","T187331-","C187332-","G187333-","A187334-","G187335-","T187336-","A187337-","T187338-","A187339-","G187340-","G187341-","A187342-","A187343-","G187344-","T187345-","A187346-","G187347-","T187348-","A187349-","T187350-","T187351-","A187352-","C187353-","C187354-","A187355-","T187356-","A187357-","T187358-","C187359-","A187360-","A187361-","C187362-","T187363-","T187364-","C187365-","C187366-","G187367-","A187368-","G187369-","T187370-","T187371-","A187372-","A187373-","C187374-","A187375-","A187376-","T187377-","T187378-","A187379-","C187380-","T187381-","C187382-","T187383-","A187384-","A187385-","A187386-","A187387-","C187388-","A187389-","T187390-","G187391-","A187392-","G187393-","G187394-","A187395-","T187396-","T187397-","G187398-","T187399-","A187400-","C187401-","T187402-","C187403-","C187404-","T187405-","G187406-","T187407-","C187408-","T187409-","T187410-","T187411-","A187412-","T187413-","T187414-","G187415-","G187416-","A187417-","G187418-","A187419-","T187420-","C187421-","A187422-","C187423-","T187424-","A187425-","T187426-","T187427-","T187428-","A187429-","G187430-","T187431-","C187432-","G187433-","T187434-","T187435-","G187436-","A187437-","T187438-","A187439-","A187440-","A187441-","C187442-","T187443-","A187444-","G187445-","T187446-","A187447-","A187448-","C187449-","C187450-","T187451-","C187452-","A187453-","G187454-","G187455-","T187456-","T187457-","T187458-","C187459-","T187460-","T187461-","T187462-","A187463-","C187464-","A187465-","A187466-","A187467-","C187468-","G187469-","A187470-","T187471-","A187472-","A187473-","A187474-","G187475-","T187476-","A187477-","C187478-","A187479-","A187480-","C187481-","A187482-","T187483-","C187484-","A187485-","A187486-","G187487-","A187488-","C187489-","C187490-","T187491-","C187492-","A187493-","C187494-","A187495-","A187496-","C187497-","A187498-","C187499-","A187500-","G187501-","T187502-","G187503-","C187504-","A187505-","A187506-","G187507-","A187508-","T187509-","T187510-","A187511-","A187512-","T187513-","C187514-","T187515-","A187516-","G187517-","A187518-","A187519-","A187520-","T187521-","C187522-","A187523-","A187524-","A187525-","T187526-","G187527-","T187528-","A187529-","A187530-","T187531-","T187532-","C187533-","T187534-","G187535-","G187536-","A187537-","G187538-","G187539-","A187540-","G187541-","A187542-","A187543-","T187544-","C187545-","T187546-","A187547-","G187548-","A187549-","C187550-","A187551-","A187552-","C187553-","T187554-","A187555-","A187556-","C187557-","A187558-","C187559-","C187560-","C187561-","A187562-","C187563-","G187564-","G187565-","C187566-","G187567-","A187568-","A187569-","G187570-","T187571-","A187572-","T187573-","A187574-","C187575-","T187576-","T187577-","T187578-","A187579-","T187580-","G187581-","C187582-","C187583-","T187584-","C187585-","A187586-","T187587-","T187588-","C187589-","A187590-","G187591-","A187592-","A187593-","A187594-","C187595-","G187596-","G187597-","T187598-","A187599-","A187600-","C187601-","T187602-","G187603-","T187604-","A187605-","G187606-","T187607-","A187608-","G187609-","G187610-","A187611-","G187612-","A187613-","C187614-","T187615-","G187616-","T187617-","C187618-","T187619-","C187620-","T187621-","C187622-","T187623-","A187624-","A187625-","T187626-","C187627-","T187628-","C187629-","G187630-","A187631-","T187632-","G187633-","T187634-","A187635-","T187636-","A187637-","T187638-","A187639-","T187640-","A187641-","A187642-","T187643-","A187644-","T187645-","A187646-","T187647-","A187648-","C187649-","C187650-","A187651-","A187652-","T187653-","A187654-","C187655-","G187656-","G187657-","A187658-","C187659-","G187660-","C187661-","G187662-","A187663-","T187664-","A187665-","T187666-","A187667-","T187668-","T187669-","C187670-","C187671-","G187672-","A187673-","C187674-","A187675-","T187676-","G187677-","A187678-","A187679-","T187680-","G187681-","G187682-","C187683-","G187684-","T187685-","C187686-","G187687-","C187688-","T187689-","T187690-","A187691-","T187692-","C187693-","A187694-","T187695-","A187696-","T187697-","G187698-","T187699-","T187700-","A187701-","T187702-","A187703-","T187704-","C187705-","C187706-","T187707-","A187708-","A187709-","A187710-","T187711-","G187712-","T187713-","T187714-","G187715-","A187716-","T187717-","C187718-","A187719-","T187720-","A187721-","T187722-","T187723-","C187724-","C187725-","A187726-","C187727-","A187728-","A187729-","A187730-","T187731-","G187732-","A187733-","T187734-","T187735-","G187736-","T187737-","G187738-","A187739-","A187740-","C187741-","G187742-","A187743-","G187744-","A187745-","T187746-","T187747-","A187748-","A187749-","A187750-","T187751-","C187752-","A187753-","T187754-","C187755-","T187756-","A187757-","A187758-","C187759-","A187760-","A187761-","A187762-","T187763-","A187764-","A187765-","T187766-","T187767-","A187768-","G187769-","T187770-","T187771-","T187772-","T187773-","T187774-","T187775-","A187776-","T187777-","G187778-","A187779-","C187780-","A187781-","T187782-","T187783-","A187784-","A187785-","C187786-","A187787-","T187788-","A187789-","T187790-","A187791-","A187792-","T187793-","A187794-","A187795-","A187796-","T187797-","A187798-","A187799-","A187800-","T187801-","T187802-","A187803-","A187804-","T187805-","C187806-","A187807-","T187808-","T187809-","A187810-","T187811-","T187812-","G187813-","A187814-","C187815-","T187816-","T187817-","A187818-","A187819-","C187820-","G187821-","A187822-","T187823-","G187824-","A187825-","C187826-","G187827-","A187828-","A187829-","A187830-","G187831-","T187832-","T187833-","A187834-","T187835-","C187836-","A187837-","T187838-","T187839-","A187840-","T187841-","C187842-","T187843-","T187844-","A187845-","G187846-","G187847-","A187848-","T187849-","T187850-","C187851-","T187852-","T187853-","G187854-","A187855-","T187856-","T187857-","A187858-","T187859-","T187860-","A187861-","A187862-","T187863-","A187864-","C187865-","A187866-","A187867-","A187868-","T187869-","T187870-","C187871-","G187872-","T187873-","T187874-","G187875-","T187876-","G187877-","T187878-","C187879-","T187880-","A187881-","T187882-","G187883-","A187884-","A187885-","A187886-","T187887-","G187888-","T187889-","G187890-","A187891-","A187892-","C187893-","A187894-","A187895-","G187896-","G187897-","T187898-","G187899-","T187900-","C187901-","T187902-","C187903-","A187904-","T187905-","A187906-","T187907-","T187908-","A187909-","T187910-","A187911-","A187912-","T187913-","G187914-","C187915-","A187916-","C187917-","A187918-","A187919-","G187920-","A187921-","A187922-","T187923-","T187924-","A187925-","A187926-","A187927-","G187928-","T187929-","G187930-","T187931-","T187932-","G187933-","T187934-","A187935-","A187936-","A187937-","C187938-","T187939-","A187940-","T187941-","C187942-","T187943-","A187944-","G187945-","C187946-","C187947-","A187948-","G187949-","G187950-","A187951-","A187952-","C187953-","A187954-","T187955-","A187956-","T187957-","T187958-","C187959-","A187960-","G187961-","A187962-","T187963-","T187964-","A187965-","T187966-","C187967-","G187968-","A187969-","T187970-","G187971-","T187972-","G187973-","A187974-","T187975-","A187976-","A187977-","A187978-","T187979-","A187980-","C187981-","A187982-","G187983-","C187984-","G187985-","A187986-","T187987-","A187988-","C187989-","C187990-","A187991-","T187992-","C187993-","T187994-","G187995-","T187996-","G187997-","G187998-","A187999-","C188000-","A188001-","T188002-","T188003-","G188004-","T188005-","C188006-","C188007-","A188008-","A188009-","G188010-","T188011-","G188012-","A188013-","C188014-","A188015-","C188016-","A188017-","T188018-","T188019-","C188020-","A188021-","C188022-","G188023-","T188024-","C188025-","A188026-","A188027-","T188028-","A188029-","T188030-","A188031-","T188032-","A188033-","A188034-","T188035-","C188036-","G188037-","T188038-","T188039-","C188040-","T188041-","C188042-","C188043-","T188044-","C188045-","G188046-","G188047-","T188048-","G188049-","T188050-","C188051-","A188052-","T188053-","A188054-","G188055-","T188056-","T188057-","G188058-","T188059-","A188060-","G188061-","A188062-","G188063-","G188064-","T188065-","C188066-","A188067-","C188068-","A188069-","C188070-","C188071-","T188072-","T188073-","G188074-","T188075-","A188076-","C188077-","A188078-","C188079-","C188080-","T188081-","A188082-","C188083-","C188084-","A188085-","C188086-","A188087-","A188088-","A188089-","T188090-","A188091-","G188092-","A188093-","A188094-","T188095-","A188096-","T188097-","G188098-","T188099-","C188100-","A188101-","T188102-","T188103-","G188104-","T188105-","G188106-","A188107-","C188108-","T188109-","C188110-","G188111-","A188112-","A188113-","T188114-","A188115-","G188116-","T188117-","T188118-","A188119-","T188120-","C188121-","G188122-","T188123-","C188124-","T188125-","C188126-","C188127-","T188128-","T188129-","A188130-","A188131-","A188132-","G188133-","C188134-","T188135-","T188136-","C188137-","T188138-","G188139-","A188140-","T188141-","G188142-","G188143-","T188144-","A188145-","A188146-","C188147-","T188148-","G188149-","T188150-","G188151-","T188152-","T188153-","A188154-","C188155-","A188156-","T188157-","G188158-","T188159-","G188160-","C188161-","T188162-","C188163-","C188164-","T188165-","A188166-","A188167-","A188168-","A188169-","C188170-","A188171-","A188172-","A188173-","A188174-","T188175-","A188176-","T188177-","G188178-","G188179-","T188180-","C188181-","G188182-","T188183-","G188184-","T188185-","G188186-","T188187-","A188188-","C188189-","G188190-","G188191-","A188192-","A188193-","A188194-","G188195-","A188196-","A188197-","A188198-","G188199-","G188200-","A188201-","G188202-","A188203-","A188204-","A188205-","A188206-","T188207-","G188208-","A188209-","T188210-","A188211-","T188212-","G188213-","G188214-","A188215-","A188216-","T188217-","A188218-","C188219-","C188220-","A188221-","T188222-","T188223-","T188224-","G188225-","T188226-","A188227-","A188228-","G188229-","A188230-","A188231-","A188232-","T188233-","G188234-","T188235-","C188236-","G188237-","G188238-","A188239-","A188240-","G188241-","G188242-","G188243-","T188244-","A188245-","C188246-","T188247-","T188248-","A188249-","T188250-","T188251-","C188252-","A188253-","G188254-","A188255-","T188256-","A188257-","T188258-","T188259-","G188260-","T188261-","A188262-","T188263-","C188264-","T188265-","G188266-","A188267-","C188268-","T188269-","C188270-","T188271-","G188272-","A188273-","T188274-","C188275-","A188276-","A188277-","T188278-","G188279-","T188280-","A188281-","A188282-","A188283-","C188284-","C188285-","T188286-","A188287-","T188288-","G188289-","A188290-","C188291-","A188292-","A188293-","G188294-","A188295-","T188296-","A188297-","A188298-","G188299-","A188300-","C188301-","T188302-","T188303-","A188304-","C188305-","T188306-","C188307-","G188308-","C188309-","A188310-","T188311-","C188312-","T188313-","A188314-","C188315-","T188316-","G188317-","G188318-","A188319-","T188320-","A188321-","G188322-","A188323-","C188324-","A188325-","T188326-","A188327-","A188328-","A188329-","T188330-","A188331-","T188332-","C188333-","C188334-","T188335-","C188336-","C188337-","T188338-","C188339-","G188340-","T188341-","A188342-","A188343-","T188344-","A188345-","A188346-","T188347-","G188348-","A188349-","A188350-","A188351-","T188352-","A188353-","T188354-","A188355-","A188356-","T188357-","A188358-","T188359-","A188360-","C188361-","A188362-","C188363-","T188364-","A188365-","A188366-","T188367-","T188368-","A188369-","T188370-","T188371-","A188372-","A188373-","T188374-","A188375-","T188376-","C188377-","A188378-","A188379-","T188380-","C188381-","G188382-","A188383-","G188384-","T188385-","A188386-","T188387-","T188388-","A188389-","A188390-","C188391-","A188392-","T188393-","A188394-","T188395-","A188396-","A188397-","G188398-","T188399-","T188400-","A188401-","T188402-","T188403-","T188404-","T188405-","T188406-","A188407-","A188408-","A188409-","C188410-","C188411-","C188412-","C188413-","T188414-","T188415-","T188416-","T188417-","G188418-","G188419-","G188420-","T188421-","T188422-","C188423-","C188424-","G188425-","T188426-","C188427-","C188428-","T188429-","A188430-","A188431-","A188432-","C188433-","G188434-","G188435-","C188436-","G188437-","T188438-","T188439-","T188440-","C188441-","G188442-","G188443-","T188444-","C188445-","T188446-","G188447-","T188448-","G188449-","T188450-","C188451-","G188452-","C188453-","C188454-","A188455-","C188456-","C188457-","A188458-","T188459-","G188460-","G188461-","T188462-","C188463-","A188464-","C188465-","A188466-","C188467-","C188468-","G188469-","A188470-","G188471-","C188472-","C188473-","T188474-","C188475-","T188476-","G188477-","C188478-","G188479-","T188480-","G188481-","C188482-","T188483-","C188484-","C188485-","T188486-","C188487-","C188488-","A188489-","T188490-","C188491-","G188492-","A188493-","G188494-","G188495-","A188496-","C188497-","G188498-","A188499-","C188500-","T188501-","T188502-","C188503-","A188504-","A188505-","C188506-","T188507-","A188508-","T188509-","G188510-","A188511-","C188512-","A188513-","G188514-","C188515-","T188516-","C188517-","G188518-","G188519-","T188520-","G188521-","G188522-","C188523-","G188524-","T188525-","C188526-","T188527-","G188528-","C188529-","C188530-","A188531-","G188532-","C188533-","G188534-","T188535-","G188536-","T188537-","A188538-","C188539-","A188540-","T188541-","A188542-","C188543-","G188544-","A188545-","A188546-","T188547-","G188548-","G188549-","C188550-","A188551-","T188552-","T188553-","T188554-","C188555-","T188556-","A188557-","A188558-","G188559-","A188560-","A188561-","A188562-","A188563-","G188564-","T188565-","C188566-","T188567-","A188568-","C188569-","G188570-","G188571-","T188572-","A188573-","T188574-","C188575-","C188576-","T188577-","T188578-","T188579-","C188580-","T188581-","A188582-","C188583-","A188584-","A188585-","T188586-","T188587-","T188588-","C188589-","C188590-","T188591-","T188592-","T188593-","A188594-","A188595-","C188596-","A188597-","A188598-","C188599-","G188600-","G188601-","C188602-","A188603-","A188604-","C188605-","A188606-","G188607-","C188608-","T188609-","G188610-","C188611-","A188612-","G188613-","T188614-","A188615-","T188616-","T188617-","T188618-","T188619-","T188620-","A188621-","T188622-","A188623-","C188624-","T188625-","T188626-","T188627-","G188628-","A188629-","A188630-","T188631-","G188632-","C188633-","A188634-","T188635-","C188636-","G188637-","G188638-","A188639-","C188640-","A188641-","T188642-","T188643-","T188644-","A188645-","T188646-","A188647-","C188648-","A188649-","A188650-","G188651-","G188652-","G188653-","A188654-","G188655-","T188656-","C188657-","C188658-","T188659-","G188660-","T188661-","T188662-","C188663-","T188664-","A188665-","A188666-","T188667-","A188668-","T188669-","T188670-","G188671-","G188672-","C188673-","A188674-","T188675-","C188676-","A188677-","A188678-","T188679-","G188680-","T188681-","T188682-","C188683-","G188684-","G188685-","A188686-","T188687-","C188688-","T188689-","A188690-","T188691-","A188692-","G188693-","G188694-","C188695-","T188696-","T188697-","G188698-","A188699-","T188700-","T188701-","T188702-","T188703-","C188704-","G188705-","C188706-","A188707-","T188708-","T188709-","G188710-","A188711-","C188712-","T188713-","T188714-","T188715-","A188716-","C188717-","A188718-","C188719-","A188720-","G188721-","A188722-","C188723-","A188724-","T188725-","G188726-","A188727-","A188728-","C188729-","A188730-","T188731-","C188732-","C188733-","C188734-","C188735-","T188736-","G188737-","A188738-","A188739-","T188740-","C188741-","T188742-","G188743-","T188744-","A188745-","C188746-","A188747-","T188748-","A188749-","C188750-","T188751-","T188752-","T188753-","G188754-","T188755-","G188756-","G188757-","A188758-","T188759-","T188760-","T188761-","A188762-","C188763-","A188764-","C188765-","T188766-","G188767-","T188768-","T188769-","A188770-","G188771-","A188772-","A188773-","T188774-","C188775-","T188776-","C188777-","T188778-","A188779-","A188780-","C188781-","G188782-","C188783-","T188784-","G188785-","G188786-","C188787-","C188788-","T188789-","C188790-","T188791-","G188792-","T188793-","T188794-","G188795-","T188796-","T188797-","A188798-","C188799-","T188800-","T188801-","T188802-","C188803-","T188804-","A188805-","T188806-","G188807-","A188808-","T188809-","G188810-","C188811-","A188812-","C188813-","G188814-","T188815-","A188816-","T188817-","C188818-","G188819-","T188820-","T188821-","A188822-","T188823-","G188824-","C188825-","A188826-","A188827-","G188828-","C188829-","T188830-","T188831-","T188832-","C188833-","A188834-","T188835-","G188836-","T188837-","T188838-","G188839-","A188840-","C188841-","T188842-","A188843-","C188844-","T188845-","G188846-","C188847-","A188848-","G188849-","T188850-","G188851-","T188852-","T188853-","T188854-","C188855-","T188856-","T188857-","G188858-","C188859-","T188860-","C188861-","T188862-","G188863-","A188864-","C188865-","T188866-","A188867-","C188868-","A188869-","T188870-","A188871-","T188872-","A188873-","C188874-","T188875-","C188876-","T188877-","A188878-","C188879-","A188880-","A188881-","T188882-","C188883-","A188884-","A188885-","A188886-","G188887-","A188888-","G188889-","A188890-","G188891-","A188892-","T188893-","T188894-","T188895-","C188896-","A188897-","G188898-","T188899-","A188900-","A188901-","A188902-","C188903-","T188904-","T188905-","G188906-","T188907-","A188908-","A188909-","C188910-","A188911-","G188912-","G188913-","A188914-","T188915-","T188916-","G188917-","T188918-","T188919-","T188920-","G188921-","C188922-","T188923-","G188924-","C188925-","T188926-","T188927-","T188928-","C188929-","T188930-","G188931-","G188932-","A188933-","T188934-","-196616A"],"OPG023":["D392N"],"OPG057":["E353K"]},"labels":{"aa":"OPG023: D392N; OPG057: E353K"}}},{"name":"OP612688","node_attrs":{"div":522,"accession":"OP612688","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/104/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-11-02"},"strain_display":{"value":"Nigeria/OP612688/2019-11-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","G1126A","G2039A","G2152A","C6948T","C47224T","T76087-","C77726T","C143845T","G152431A","C166786T","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","G184037T","C184535T","C195058T","C195171T","C196084T"],"OPG002":["S238L"],"OPG002_dup":["S238L"],"OPG066":["E69K"],"OPG099":["S21F"],"OPG192":["S19L"]},"labels":{"aa":"OPG002: S238L; OPG002_dup: S238L; OPG066: E69K; OPG099: S21F; OPG192: S19L"}}},{"name":"OP612681","node_attrs":{"div":520,"accession":"OP612681","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/039/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-04-20"},"strain_display":{"value":"Nigeria/OP612681/2019-04-20"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A1231G","G22971A","G23711A","G33177A","T76087-","G77635A","C83496T","C90945T","T121121-","G138571A","A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","T187080-"],"OPG098":["D246N"],"OPG156":["T280I"]},"labels":{"aa":"OPG098: D246N; OPG156: T280I"}}},{"name":"OP612674","node_attrs":{"div":518,"accession":"OP612674","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/003/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-01-12"},"strain_display":{"value":"Nigeria/OP612674/2019-01-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C11555T","G28645A","G75967A","T76087-","G94840A","A173292-","T173293-","A173294-","T173295-","A173296-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","C188503T","A196612-","A196613-","A196614-","A196615-"],"OPG023":["R449Q"],"OPG115":["E61K"]},"labels":{"aa":"OPG023: R449Q; OPG115: E61K"}}},{"name":"NODE_0000084","node_attrs":{"div":514,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G151929A","-196616A"],"OPG178":["E141K"]},"labels":{"aa":"OPG178: E141K"}},"children":[{"name":"OL504742","node_attrs":{"div":521,"accession":"OL504742","author":{"author":"Atkinson,B.,Pottage,T.,Ngabo,D.,Crook,A.,Pitman,J.,Summers,S.,Pullan,S.,Lewandowski,K.,Furneaux,J.,Davies,K.,Brooks,T.","value":"Atkinson,B.,Pottage,T.,Ngabo,D.,Crook,A.,Pitman,J.,Summers,S.,Pullan,S.,Lewandowski,K.,Furneaux,J.,Davies,K.,Brooks,T."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"2095"},"date":{"value":"2019-12-XX"},"strain_display":{"value":"United Kingdom/OL504742/2019-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C13065T","C29887T","G61329A","C72206T","G103431A","C165369T","-173314A","-173315T","-173316A","-173317T","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G188949A","T192184C"],"OPG024":["G55E"],"OPG092":["E248K"],"OPG123":["S547L"],"OPG190":["S83F"]},"labels":{"aa":"OPG024: G55E; OPG092: E248K; OPG123: S547L; OPG190: S83F"}}},{"name":"NODE_0000085","node_attrs":{"div":515,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C39767T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A"]}},"children":[{"name":"MT903342","node_attrs":{"div":517,"accession":"MT903342","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"Singapore"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-Singapore"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-05-XX"},"strain_display":{"value":"Singapore/MT903342/2019-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["-608T","C43927T","C170573T","-173297T","-173298A","-173299T","-173314A","-173315T","-173316A","-173317T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"],"OPG064":["E658K"],"OPG198":["S179L"]},"labels":{"aa":"OPG064: E658K; OPG198: S179L"}}},{"name":"OP612685","node_attrs":{"div":515,"accession":"OP612685","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/052/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-05-29"},"strain_display":{"value":"Nigeria/OP612685/2019-05-29"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-","A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","-196617A"]}}}]}]},{"name":"NODE_0000086","node_attrs":{"div":515,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G25661A","C39119T","-173297T","-173298A","-173299T","-173314A","-173315T","-173316A","-173317T"]}},"children":[{"name":"OP612679","node_attrs":{"div":523,"accession":"OP612679","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/018/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-03-14"},"strain_display":{"value":"Nigeria/OP612679/2019-03-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C8500T","G79538A","G81354A","G84416A","C88736T","G100642A","C138791T","C161616T","-196616A","-196617A"],"OPG102":["D152N"],"OPG105":["E77K"],"OPG109":["E238K"],"OPG119":["R86K"],"OPG156":["D207N"]},"labels":{"aa":"OPG102: D152N; OPG105: E77K; OPG109: E238K; OPG119: R86K; OPG156: D207N"}}},{"name":"NODE_0000087","node_attrs":{"div":516,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T607-","G162243A","A196615-"]}},"children":[{"name":"MT903345","node_attrs":{"div":516,"accession":"MT903345","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"United Kingdom"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-UK_P3"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-09-XX"},"strain_display":{"value":"United Kingdom/MT903345/2018-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"MT903344","node_attrs":{"div":516,"accession":"MT903344","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"United Kingdom"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-UK_P2"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-09-XX"},"strain_display":{"value":"United Kingdom/MT903344/2018-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"]}}},{"name":"NODE_0000088","node_attrs":{"div":519,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G1262A","C3818T","G124130A","C128698T","T133102-","T133177-","C133178-","T133179-","T133180-","T133181-","C133182-","T133183-","C133184-","A133185-","A133186-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179177T","-179178A","G193392A","C195948T"],"OPG001":["S105L"],"OPG001_dup":["S105L"],"OPG003":["D264N"],"OPG003_dup":["D264N"],"OPG145":["E62K"],"OPG150":["S307L"]},"labels":{"aa":"OPG001: S105L; OPG001_dup: S105L; OPG003: D264N; OPG003_dup: D264N; OPG145: E62K; OPG150: S307L"}},"children":[{"name":"OP612687","node_attrs":{"div":524,"accession":"OP612687","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/058/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-07-11"},"strain_display":{"value":"Nigeria/OP612687/2019-07-11"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","C756T","G2039A","G168365A","A173288-","T173289-","-179172C","-179173A","-179174T","-179175T","-179176A","C188605A","A188606C","G188607A","T193455A","C195171T","G196454-","A196614-"],"OPG002":["S238L"],"OPG002_dup":["S238L"],"OPG003_dup":["L285I"],"OPG195":["E46K"]},"labels":{"aa":"OPG002: S238L; OPG002_dup: S238L; OPG003_dup: L285I; OPG195: E46K"}}},{"name":"NODE_0000089","node_attrs":{"div":520,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G81275A"]}},"children":[{"name":"OP612686","node_attrs":{"div":521,"accession":"OP612686","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/053/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-06-26"},"strain_display":{"value":"Nigeria/OP612686/2019-06-26"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-607T","T76087-","G88640A","-179172C","-179173A","-179174T","-179175T","-179176A","-196615A","-196616A","-196617A"],"OPG109":["R270C"]},"labels":{"aa":"OPG109: R270C"}}},{"name":"NODE_0000090","node_attrs":{"div":545,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G2591A","G3522A","C7771T","G14000T","G15428A","G21723A","G30367A","G31053A","G34459A","G37202A","G38360A","C38662T","G52885A","G54117A","G54635A","G64297A","C73066T","C82373T","G82451A","G95034A","G124674A","-133102T","C162331T","-173290A","-173291T","-173292A","-173293T","-173294A","-173295T","-173296A","-173297T","-173298A","-173299T","-173300A","-173301T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","G178133A","G181980A","G186578A","C193688T","C194619T"],"OPG002":["S54F"],"OPG002_dup":["S54F"],"OPG025":["A423D"],"OPG047":["R48C"],"OPG053":["P78S"],"OPG056":["E125K"],"OPG071":["L108F"],"OPG072":["D56N"],"OPG093":["S30L"],"OPG145":["R243Q"],"OPG210":["D209N","M1741I"]},"labels":{"aa":"OPG002: S54F; OPG002_dup: S54F; OPG025: A423D; OPG047: R48C; OPG053: P78S; OPG056: E125K; OPG071: L108F; OPG072: D56N; OPG093: S30L; OPG145: R243Q; OPG210: D209N, M1741I","clade":"A.1.1"}},"children":[{"name":"ON676708","node_attrs":{"div":548,"accession":"ON676708","author":{"author":"Gigante,C.M.,Myers,R.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Blythe,D.,Li,Y.","value":"Gigante,C.M.,Myers,R.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Blythe,D.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1.1"},"strain":{"value":"MPXV_USA_2021_MD"},"host":{"value":"Homo sapiens"},"date":{"value":"2021-11-XX"},"strain_display":{"value":"USA/ON676708/2021-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C79348T","C86979T","C133714T","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"NODE_0000091","node_attrs":{"div":556,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G3111A","C39139T","G73239A","G74205A","G77383A","C84587T","C150469T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A151461C","G155795A","G170262A","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C183519T","C194099T"],"OPG057":["E353K"],"OPG093":["D88N"],"OPG094":["M142I"],"OPG098":["E162K"],"OPG176":["H221Y"],"OPG210":["P722S"]},"labels":{"aa":"OPG057: E353K; OPG093: D88N; OPG094: M142I; OPG098: E162K; OPG176: H221Y; OPG210: P722S","clade":"B.1"}},"children":[{"name":"LC722946","node_attrs":{"div":559,"accession":"LC722946","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"country":{"value":"Japan"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/TKY220091/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Japan/LC722946/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["C13653T","C116100T","G150376A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG025":["D539N"],"OPG176":["D190N"]},"labels":{"aa":"OPG025: D539N; OPG176: D190N"}}},{"name":"OP160532","node_attrs":{"div":557,"accession":"OP160532","author":{"author":"Tutu van Furth AM,van der Kuip M,van Els AL,Fievez LC,van Rijckevorsel GG,van den Ouden A,Jonges M,Welkers MR,Welkers,M.,Jonges,M.","value":"Tutu van Furth AM,van der Kuip M,van Els AL,Fievez LC,van Rijckevorsel GG,van den Ouden A,Jonges M,Welkers MR,Welkers,M.,Jonges,M."},"country":{"value":"Netherlands"},"institution":{"value":"Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Netherlands/NH-AUMC-0001/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Netherlands/OP160532/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A148207T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G191845A","A196614-"],"OPG173":["E57D"]},"labels":{"aa":"OPG173: E57D"}}},{"name":"OP133006","node_attrs":{"div":560,"accession":"OP133006","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"country":{"value":"Austria"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV/Austria/MUW1532243/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-06"},"strain_display":{"value":"Austria/OP133006/2022-07-06"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A28532-","C122511T","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","G151801A","C153984T","G169886A","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG044":["M148-"],"OPG143":["E269K"],"OPG178":["G98E"],"OPG197":["E73K"]},"labels":{"aa":"OPG044: M148-; OPG143: E269K; OPG178: G98E; OPG197: E73K"}}},{"name":"OP062230","node_attrs":{"div":557,"accession":"OP062230","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Jolly,G.,Griffiths,E.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Jolly,G.,Griffiths,E.,Charest,H.,Levade,I.,Fafard,J."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3864/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-22"},"strain_display":{"value":"Canada/OP062230/2022-06-22"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C57790T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG077":["R265K"]},"labels":{"aa":"OPG077: R265K"}}},{"name":"OP019275","node_attrs":{"div":559,"accession":"OP019275","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"country":{"value":"Austria"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV/Austria/MUW1525179/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-10"},"strain_display":{"value":"Austria/OP019275/2022-06-10"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","A107070C","C144546T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G190319A","-196615A","-196616A","-196617A"],"OPG166":["S50F"]},"labels":{"aa":"OPG166: S50F"}}},{"name":"ON959134","node_attrs":{"div":557,"accession":"ON959134","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_USA_2022_NY003"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/ON959134/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C98368T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON927243","node_attrs":{"div":557,"accession":"ON927243","author":{"author":"Palomino-Cabrera,R.,Penas-Utrilla,D.,Buenestado-Serrano,S.,Perez-Lago,L.,Herranz Martin,M.,Veintimilla,C.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Palomino-Cabrera,R.,Penas-Utrilla,D.,Buenestado-Serrano,S.,Perez-Lago,L.,Herranz Martin,M.,Veintimilla,C.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"country":{"value":"Spain"},"institution":{"value":"HGUGM, Microbial Genomics"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MpxV/Spain/MD-HGUGM-6642566/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-21"},"strain_display":{"value":"Spain/ON927243/2022-06-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","C187154T"]}}},{"name":"ON880524","node_attrs":{"div":556,"accession":"ON880524","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3080/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-26"},"strain_display":{"value":"Canada/ON880524/2022-05-26"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"ON838940","node_attrs":{"div":556,"accession":"ON838940","author":{"author":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J.","value":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J."},"country":{"value":"Spain"},"institution":{"value":"Hospital Universitario La Paz, Microbiology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"4061"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-20"},"strain_display":{"value":"Spain/ON838940/2022-05-20"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON872184","node_attrs":{"div":561,"accession":"ON872184","author":{"author":"Fletcher,N.,Gonzalez,G.,Meredith,L.,Purves,K.,Carr,M.,Dean,J.,Keogan,B.,Crowley,B.,Lyons,F.,O'Reilly,S.,Gautier,V.,Mallon,P.,Gordon,S.,Connell,J.,De Gascun,C.F.","value":"Fletcher,N.,Gonzalez,G.,Meredith,L.,Purves,K.,Carr,M.,Dean,J.,Keogan,B.,Crowley,B.,Lyons,F.,O'Reilly,S.,Gautier,V.,Mallon,P.,Gordon,S.,Connell,J.,De Gascun,C.F."},"country":{"value":"Ireland"},"institution":{"value":"University College Dublin, National Virus Reference Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"WA-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Ireland/ON872184/2022-05-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T48785C","G49636A","C50017T","T72809C","G178541A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG068":["G479E"],"OPG069":["T11I"],"OPG092":["K47E"]},"labels":{"aa":"OPG068: G479E; OPG069: T11I; OPG092: K47E"}}},{"name":"ON751962","node_attrs":{"div":559,"accession":"ON751962","author":{"author":"Claro,I.M.,de Lima,E.L.,Romano,C.M.,Candido,D.S.,Lindoso,J.A.L.,Barra,L.A.C.,Borges,L.M.S.,Medeiros,L.A.,Tomishige,M.Y.S.,Ramundo,M.S.,Moutinho,T.,da Silva,A.J.D.,Rodrigues,C.C.M.,de Azevedo,L.C.F.,Villas-Boas,L.S.,da Silva,C.A.M.,Coletti,T.M.,O'Toole,A.,Quick,J.,Loman,N.,Rambaut,A.,Faria,N.R.,Figueiredo-Mello,C.,Sabino,E.C.","value":"Claro,I.M.,de Lima,E.L.,Romano,C.M.,Candido,D.S.,Lindoso,J.A.L.,Barra,L.A.C.,Borges,L.M.S.,Medeiros,L.A.,Tomishige,M.Y.S.,Ramundo,M.S.,Moutinho,T.,da Silva,A.J.D.,Rodrigues,C.C.M.,de Azevedo,L.C.F.,Villas-Boas,L.S.,da Silva,C.A.M.,Coletti,T.M.,O'Toole,A.,Quick,J.,Loman,N.,Rambaut,A.,Faria,N.R.,Figueiredo-Mello,C.,Sabino,E.C."},"country":{"value":"Brazil"},"institution":{"value":"Imperial College London, School of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/BR0001/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-07"},"strain_display":{"value":"Brazil/ON751962/2022-06-07"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G10118A","C15004T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G169928A","G173575-","A173576-","G173577-","A173578-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG021":["E178K"],"OPG197":["D87N"]},"labels":{"aa":"OPG021: E178K; OPG197: D87N"}}},{"name":"ON649710","node_attrs":{"div":556,"accession":"ON649710","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0027/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-18"},"strain_display":{"value":"Portugal/ON649710/2022-05-18"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"ON619836","node_attrs":{"div":558,"accession":"ON619836","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"Research & Evaluation, UKHSA, UK"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_UK_2022_2"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"United Kingdom/ON619836/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C7259T","C33832T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG052":["R55Q"]},"labels":{"aa":"OPG052: R55Q"}}},{"name":"ON622713","node_attrs":{"div":557,"accession":"ON622713","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"Microbiology, Immunology & Transplantation, KU Leuven, Rega Institute, Belgium"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPX/UZ_REGA_2/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-22"},"strain_display":{"value":"Belgium/ON622713/2022-05-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C4629T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G192581A"]}}},{"name":"ON614676","node_attrs":{"div":556,"accession":"ON614676","author":{"author":"Gruber,C.E.M.,Rueca,M.,Gramigna,G.,Carletti,F.,Butera,O.,Fabeni,L.,Specchiarello,E.,Meschi,S.,Colavita,F.,Minosse,C.,Francalancia,M.,Lapa,D.,Garbuglia,A.R.,Giombini,E.","value":"Gruber,C.E.M.,Rueca,M.,Gramigna,G.,Carletti,F.,Butera,O.,Fabeni,L.,Specchiarello,E.,Meschi,S.,Colavita,F.,Minosse,C.,Francalancia,M.,Lapa,D.,Garbuglia,A.R.,Giombini,E."},"country":{"value":"Italy"},"institution":{"value":"Laboratory of Virology, INMI Lazzaro Spallanzani IRCCS, Italy"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"INMI-Pt1"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-18"},"strain_display":{"value":"Italy/ON614676/2022-05-18"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"ON615424","node_attrs":{"div":558,"accession":"ON615424","author":{"author":"Oude Munnink,B.B.,Boter,M.,Wellers,B.,Molenkamp,R.,Sikkema,R.S.,Koopmans,M.","value":"Oude Munnink,B.B.,Boter,M.,Wellers,B.,Molenkamp,R.,Sikkema,R.S.,Koopmans,M."},"country":{"value":"Netherlands"},"institution":{"value":"Public Health Virology, Erasmus Medical Centre, The Netherlands"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_2022_NL001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Netherlands/ON615424/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155611A","G171003A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","G179362-","G179363-","-196615A"],"OPG199":["E6K"]},"labels":{"aa":"OPG199: E6K"}}},{"name":"ON595760","node_attrs":{"div":556,"accession":"ON595760","author":{"author":"Laubscher,F.,Chudzinski,V.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinski,V.,Schibler,M.,Kaiser,L.,Renzoni,A."},"country":{"value":"Switzerland"},"institution":{"value":"Laboratory of Viorology, University Hospital of Geneva, Switzerland"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV-CH-38134631/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-19"},"strain_display":{"value":"Switzerland/ON595760/2022-05-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","T133101-","T133102-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"]}}},{"name":"OP341487","node_attrs":{"div":560,"accession":"OP341487","author":{"author":"Welkers,M.,Jonges,M.,de Regt,M.,Ooijevaar,R.,Wagemakers,A.","value":"Welkers,M.,Jonges,M.,de Regt,M.,Ooijevaar,R.,Wagemakers,A."},"country":{"value":"Netherlands"},"institution":{"value":"Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Netherlands/NH-AUMC-0060/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-05"},"strain_display":{"value":"Netherlands/OP341487/2022-08-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C96773T","C109432T","C114985T","C142356T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG117":["S242L"],"OPG129":["D525N"],"OPG133":["D238N"],"OPG163":["S52F"]},"labels":{"aa":"OPG117: S242L; OPG129: D525N; OPG133: D238N; OPG163: S52F"}}},{"name":"OP324507","node_attrs":{"div":558,"accession":"OP324507","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0194/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-27"},"strain_display":{"value":"Portugal/OP324507/2022-06-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","C142461T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G151793C","-196615A"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG163":["S87L"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG163: S87L"}}},{"name":"OP310062","node_attrs":{"div":556,"accession":"OP310062","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MpxV/human/USA/WA-UW-089836/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP310062/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP245340","node_attrs":{"div":557,"accession":"OP245340","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPX/PT0090/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-21"},"strain_display":{"value":"Portugal/OP245340/2022-07-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C774-","G775-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159001A","-179175T","T179244-","C179245-","G179246-","T179247-","A196659-","T196660-"],"OPG185":["D29N"]},"labels":{"aa":"OPG185: D29N"}}},{"name":"OP205093","node_attrs":{"div":556,"accession":"OP205093","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_UK_2022_9000105"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-14"},"strain_display":{"value":"United Kingdom/OP205093/2022-06-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP422342","node_attrs":{"div":559,"accession":"OP422342","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"country":{"value":"Austria"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV/Austria/MUW1539124/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-02"},"strain_display":{"value":"Austria/OP422342/2022-08-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G28490A","G102694A","C110960T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG044":["D134N"]},"labels":{"aa":"OPG044: D134N"}}},{"name":"OP382478","node_attrs":{"div":557,"accession":"OP382478","author":{"author":"Colson,P.","value":"Colson,P."},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV-IHU00001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-13"},"strain_display":{"value":"France/OP382478/2022-06-13"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C178006T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG205":["S784F"]},"labels":{"aa":"OPG205: S784F"}}},{"name":"OP382487","node_attrs":{"div":556,"accession":"OP382487","author":{"author":"Colson,P.","value":"Colson,P."},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV-IHU00010"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-18"},"strain_display":{"value":"France/OP382487/2022-07-18"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OP555554","node_attrs":{"div":559,"accession":"OP555554","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0475/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-08"},"strain_display":{"value":"Portugal/OP555554/2022-08-08"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G22039A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G170776A","C179853T"],"OPG037":["S132L"],"OPG198":["E247K"]},"labels":{"aa":"OPG037: S132L; OPG198: E247K"}}},{"name":"OP555484","node_attrs":{"div":561,"accession":"OP555484","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0388/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-12"},"strain_display":{"value":"Portugal/OP555484/2022-07-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G2174A","G25030A","G40324A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G167802A","G168044A","C195036T"],"OPG002":["S193L"],"OPG002_dup":["S193L"],"OPG040":["S150F"],"OPG193":["E157K"]},"labels":{"aa":"OPG002: S193L; OPG002_dup: S193L; OPG040: S150F; OPG193: E157K"}}},{"name":"OP536802","node_attrs":{"div":558,"accession":"OP536802","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"9000430"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536802/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","C87702T","G150484A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG176":["D226N"]},"labels":{"aa":"OPG176: D226N"}}},{"name":"OP615276","node_attrs":{"div":560,"accession":"OP615276","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00203/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-19"},"strain_display":{"value":"USA/OP615276/2022-07-19"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G59905A","G131350A","C135330T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G150732A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG080":["S705F"]},"labels":{"aa":"OPG080: S705F"}}},{"name":"OP605565","node_attrs":{"div":556,"accession":"OP605565","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Slovenia-MPXV-23-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Slovenia/OP605565/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OP605582","node_attrs":{"div":566,"accession":"OP605582","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Slovenia-MPXV-41-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Slovenia/OP605582/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C198-","-607T","C27187T","G176523A","C176524T","T176532G","G176536C","A176544T","A176550T","A176551G","T176552C","A176559C","T179059G","T179072A","G179076T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG043":["D257N"],"OPG205":["A290Y","I297L","N299C"]},"labels":{"aa":"OPG043: D257N; OPG205: A290Y, I297L, N299C"}}},{"name":"OP594206","node_attrs":{"div":558,"accession":"OP594206","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/RKI442"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP594206/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C22880T","C52956T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A163211-","A163212-","C163213-","T163214-"],"OPG038":["E94K"],"OPG071":["E495K"]},"labels":{"aa":"OPG038: E94K; OPG071: E495K"}}},{"name":"OP555658","node_attrs":{"div":558,"accession":"OP555658","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0591/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-13"},"strain_display":{"value":"Portugal/OP555658/2022-09-13"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","C136572T","C138333T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G158190A"],"OPG153":["E366K","D385-"]},"labels":{"aa":"OPG153: E366K, D385-"}}},{"name":"OP837473","node_attrs":{"div":562,"accession":"OP837473","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"VAC_INS_MPX_1054_L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-25"},"strain_display":{"value":"Colombia/OP837473/2022-10-25"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C33082T","C36405T","C40849T","G68103A","G117233A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C180361T","A197043-","T197044-","G197045-"],"OPG049":["D24N"],"OPG055":["A227T"],"OPG060":["E112K"]},"labels":{"aa":"OPG049: D24N; OPG055: A227T; OPG060: E112K"}}},{"name":"OP693649","node_attrs":{"div":558,"accession":"OP693649","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"ANT_INS_MPX_0039_L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-29"},"strain_display":{"value":"Colombia/OP693649/2022-07-29"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["A2840-","T2841-","C2842-","G127058A","G136194A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","T196865-","A196866-","G196867-"],"OPG148":["R358K"],"OPG153":["H492Y"]},"labels":{"aa":"OPG148: R358K; OPG153: H492Y"}}},{"name":"OP689665","node_attrs":{"div":556,"accession":"OP689665","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI512"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"Germany/OP689665/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP920696","node_attrs":{"div":559,"accession":"OP920696","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00358/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-05"},"strain_display":{"value":"USA/OP920696/2022-11-05"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G15683A","C104028T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G184416A"],"OPG123":["G348E"],"OPG210":["D1021N"]},"labels":{"aa":"OPG123: G348E; OPG210: D1021N"}}},{"name":"OQ411312","node_attrs":{"div":557,"accession":"OQ411312","author":{"author":"Laubscher,F.,Chudzinsk,V.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinsk,V.,Schibler,M.,Kaiser,L.,Renzoni,A."},"country":{"value":"Switzerland"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV-CH-38292866/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-08"},"strain_display":{"value":"Switzerland/OQ411312/2022-06-08"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C87764T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG109":["E562K"]},"labels":{"aa":"OPG109: E562K"}}},{"name":"OQ547754","node_attrs":{"div":556,"accession":"OQ547754","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI727"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ547754/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OR035730","node_attrs":{"div":560,"accession":"OR035730","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_124"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-20"},"strain_display":{"value":"Belgium/OR035730/2022-09-20"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C12298T","C32853T","G35385A","C169036T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG049":["G100E"]},"labels":{"aa":"OPG049: G100E"}}},{"name":"OR035720","node_attrs":{"div":557,"accession":"OR035720","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_114"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035720/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C8597T","T133101-","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ918699","node_attrs":{"div":561,"accession":"OQ918699","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00488/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-20"},"strain_display":{"value":"USA/OQ918699/2023-02-20"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G66587A","G106113A","G143857A","C144237T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C189810T"],"OPG165":["S241L"]},"labels":{"aa":"OPG165: S241L"}}},{"name":"OQ918696","node_attrs":{"div":562,"accession":"OQ918696","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00485/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-11"},"strain_display":{"value":"USA/OQ918696/2023-03-11"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G30285A","G37487A","C71193T","G119839A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C161690T","C177865T","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T179244-"],"OPG047":["P304S"],"OPG137":["E80K"],"OPG188":["S32F"],"OPG205":["S737F"]},"labels":{"aa":"OPG047: P304S; OPG137: E80K; OPG188: S32F; OPG205: S737F"}}},{"name":"OQ581848","node_attrs":{"div":557,"accession":"OQ581848","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"country":{"value":"Spain"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0006b/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-01"},"strain_display":{"value":"Spain/OQ581848/2022-07-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C133168-","T133169-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C174264T","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ570420","node_attrs":{"div":559,"accession":"OQ570420","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"country":{"value":"Italy"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"INMI-14732022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-11"},"strain_display":{"value":"Italy/OQ570420/2022-08-11"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C45203T","C88917T","C130606T","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OR449698","node_attrs":{"div":557,"accession":"OR449698","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI984"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449698/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C99954T","G150551-","A150563-","T150564-","G150565-","A150566-","T150567-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"OR264408","node_attrs":{"div":557,"accession":"OR264408","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"39_K"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-19"},"strain_display":{"value":"Australia/OR264408/2022-05-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["-607T","C21128T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-196615A"],"OPG037":["E436K"]},"labels":{"aa":"OPG037: E436K"}}},{"name":"OR264387","node_attrs":{"div":556,"accession":"OR264387","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"28_A"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-23"},"strain_display":{"value":"Australia/OR264387/2022-06-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264382","node_attrs":{"div":558,"accession":"OR264382","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"26_C"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-19"},"strain_display":{"value":"Australia/OR264382/2022-07-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["C118421T","G133806A","-179223A","-179224T","-179225A"],"OPG136":["M389I"]},"labels":{"aa":"OPG136: M389I"}}},{"name":"OX291424","node_attrs":{"div":557,"accession":"OX291424","country":{"value":"Slovakia"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"RNA"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-25"},"strain_display":{"value":"Slovakia/OX291424/2022-07-25"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","G57076A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG074":["S17L"]},"labels":{"aa":"OPG074: S17L"}}},{"name":"OX291694","node_attrs":{"div":561,"accession":"OX291694","country":{"value":"Slovakia"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"RNA"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Slovakia/OX291694/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","C15311T","C28887T","C54262T","G81015T","G141131A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG045":["E126K"],"OPG104":["T2K"]},"labels":{"aa":"OPG045: E126K; OPG104: T2K"}}},{"name":"OR759158","node_attrs":{"div":560,"accession":"OR759158","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Canada/ON-PHOL067/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759158/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G4454A","G6619A","G24622A","G70190A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C190323T","C192756T"],"OPG003":["H52Y"],"OPG003_dup":["H52Y"],"OPG040":["S286L"],"OPG089":["E109K"]},"labels":{"aa":"OPG003: H52Y; OPG003_dup: H52Y; OPG040: S286L; OPG089: E109K"}}},{"name":"OR035664","node_attrs":{"div":556,"accession":"OR035664","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_58"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-13"},"strain_display":{"value":"Belgium/OR035664/2022-06-13"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP415195","node_attrs":{"div":556,"accession":"OP415195","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPX_96X1Vd_9000217"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-03-XX"},"strain_display":{"value":"United Kingdom/OP415195/2022-03-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON649879","node_attrs":{"div":556,"accession":"ON649879","author":{"author":"Israeli,O.,Guedj-Dana,Y.,Lazar,S.,Shifman,O.,Erez,N.,Weiss,S.,Paran,N.,Israely,T.,Schuster,O.,Zvi,A.,Beth-Din,A.,Cohen Gihon,I.","value":"Israeli,O.,Guedj-Dana,Y.,Lazar,S.,Shifman,O.,Erez,N.,Weiss,S.,Paran,N.,Israely,T.,Schuster,O.,Zvi,A.,Beth-Din,A.,Cohen Gihon,I."},"country":{"value":"Israel"},"institution":{"value":"Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_ISR001_2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-20"},"strain_display":{"value":"Israel/ON649879/2022-05-20"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"ON631241","node_attrs":{"div":556,"accession":"ON631241","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"2022/2 SLO"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-24"},"strain_display":{"value":"Slovenia/ON631241/2022-05-24"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON563414","node_attrs":{"div":556,"accession":"ON563414","author":{"author":"Gigante,C.M.,Smole,S.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Brown,C.,Li,Y.","value":"Gigante,C.M.,Smole,S.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Brown,C.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_USA_2022_MA001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/ON563414/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON782022","node_attrs":{"div":556,"accession":"ON782022","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.,Sironen,T.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.,Sironen,T."},"country":{"value":"Finland"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPX-42/Finland/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-31"},"strain_display":{"value":"Finland/ON782022/2022-05-31"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"NODE_0000092","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","T4775-","A4776-","A4777-","T4779-","A4780-","A4781-","T4783-","T4784-","A4785-","T4786-","A4788-","T4790-","T4791-","A4792-","A4793-","T4795-","A4796-","A4797-","T4799-","T4800-","A4801-","T4802-","A4804-","T4806-","C77462T","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A192499-","A192500-","T192502-","A192504-","T192505-","A192506-","A192507-","T192509-","T192510-","A192511-","T192513-","T192514-","A192515-","A192516-","T192518-","A192520-","T192521-","A192522-","A192523-","T192525-","T192526-","A192527-","T192529-","T192530-","A196614-"],"OPG098":["S188F"]},"labels":{"aa":"OPG098: S188F"}},"children":[{"name":"OP378707","node_attrs":{"div":557,"accession":"OP378707","author":{"author":"Gigante,C.M.,Griffin-Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Crain,J.,Li,Y.","value":"Gigante,C.M.,Griffin-Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Crain,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_USA_2022_VA0004"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP378707/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C4778-","C4782-","G4787-","C4789-","C4794-","C4798-","G4803-","C4805-","C179154-","C179163-","G192501-","C192503-","G192508-","G192512-","G192517-","C192519-","G192524-","G192528-"]}}},{"name":"OR759183","node_attrs":{"div":560,"accession":"OR759183","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Canada/ON-PHOL095/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759183/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-606T","-4775T","-4776A","-4777A","-4779T","-4780A","-4781A","-4783T","-4784T","-4785A","-4786T","-4788A","-4790T","-4791T","-4792A","-4793A","-4795T","-4796A","-4797A","-4799T","-4800T","-4801A","-4802T","-4804A","-4806T","C111164T","A143676G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C152385T","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-192499A","-192500A","-192502T","-192504A","-192505T","-192506A","-192507A","-192509T","-192510T","-192511A","-192513T","-192514T","-192515A","-192516A","-192518T","-192520A","-192521T","-192522A","-192523A","-192525T","-192526T","-192527A","-192529T","-192530T","-196614A"],"OPG130":["E247K"],"OPG165":["N54S"]},"labels":{"aa":"OPG130: E247K; OPG165: N54S"}}}]},{"name":"NODE_0000093","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C34432T","G190695A"],"OPG016":["E96K"],"OPG053":["E87K"]},"labels":{"aa":"OPG016: E96K; OPG053: E87K"}},"children":[{"name":"OP642382","node_attrs":{"div":560,"accession":"OP642382","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"ANT-LDSP-ANT-MPX-24812-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-09"},"strain_display":{"value":"Colombia/OP642382/2022-09-09"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C67439T","G154993A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG085":["D365N"]},"labels":{"aa":"OPG085: D365N"}}},{"name":"OR126131","node_attrs":{"div":561,"accession":"OR126131","author":{"author":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C.","value":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C."},"country":{"value":"Spain"},"institution":{"value":"Hospital Ramon y Cajal, Microbiology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"HRYC_MPXV001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-21"},"strain_display":{"value":"Spain/OR126131/2022-09-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C11749-","C48324T","G101294A","C141757T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG120":["S152L"]},"labels":{"aa":"OPG120: S152L"}}}]},{"name":"NODE_0000094","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G98456A","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-179189A","T179244-","T179247-","T179248-","A179249-","T179250-","T179251-","T179253-","T179254-","T179255-","T179258-","T179260-","A179261-"],"OPG118":["G4E"]},"labels":{"aa":"OPG118: G4E"}},"children":[{"name":"OP894033","node_attrs":{"div":557,"accession":"OP894033","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI613"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP894033/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C179245-","G179246-","G179252-","G179256-","G179257-","C179259-","G181052-"],"OPG209":["G179-"]},"labels":{"aa":"OPG209: G179-"}}},{"name":"OR086985","node_attrs":{"div":560,"accession":"OR086985","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_176/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR086985/2022-07-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G18442A","C101656T","-133096T","-133097T","-133098T","-133099T","-133100T","-133101T","G170981A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-179244T","-179247T","-179248T","-179249A","-179250T","-179251T","-179253T","-179254T","-179255T","-179258T","-179260T","-179261A","A196780-","A196781-","T196782-"]}}}]},{"name":"NODE_0000095","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G53326A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}},"children":[{"name":"OQ320508","node_attrs":{"div":561,"accession":"OQ320508","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Burroughs,M.R.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Burroughs,M.R.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_USA_2022_TX0032"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ320508/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C102640T","C124036T","C136033T","C142626T","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG163":["S142L"]},"labels":{"aa":"OPG163: S142L"}}},{"name":"OR264430","node_attrs":{"div":559,"accession":"OR264430","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"51_B"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-05"},"strain_display":{"value":"Australia/OR264430/2022-09-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["C15582T","C121104T"],"OPG138":["R10K"]},"labels":{"aa":"OPG138: R10K"}}}]},{"name":"NODE_0000096","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G43620A"]}},"children":[{"name":"OQ672580","node_attrs":{"div":565,"accession":"OQ672580","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"country":{"value":"Taiwan"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/human/Taiwan/110-093354/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-XX"},"strain_display":{"value":"Taiwan/OQ672580/2023-03-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["T4795C","C39503G","A44076G","G45563A","T69121C","T80764C","A130204G","A143123G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG057":["K231N"],"OPG064":["F608S"],"OPG087":["Y89H"],"OPG104":["N86D"],"OPG164":["T116A"]},"labels":{"aa":"OPG057: K231N; OPG064: F608S; OPG087: Y89H; OPG104: N86D; OPG164: T116A"}}},{"name":"OR759224","node_attrs":{"div":558,"accession":"OR759224","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Canada/ON-PHOL137/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-01"},"strain_display":{"value":"Canada/OR759224/2022-07-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C1554T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G195656A"],"OPG001":["A8T"],"OPG001_dup":["A8T"]},"labels":{"aa":"OPG001: A8T; OPG001_dup: A8T"}}}]},{"name":"NODE_0000097","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C101074T","G138682A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A"],"OPG156":["S243F"]},"labels":{"aa":"OPG156: S243F"}},"children":[{"name":"OR086993","node_attrs":{"div":559,"accession":"OR086993","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_184/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-03"},"strain_display":{"value":"Belgium/OR086993/2022-08-03"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G178410A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR463732","node_attrs":{"div":559,"accession":"OR463732","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI767"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OR463732/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G120394A","G150551-","G150568-","A150569-","T150570-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","A181253-"],"OPG137":["E265K"]},"labels":{"aa":"OPG137: E265K"}}}]},{"name":"NODE_0000098","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C34784T","C101418T","G109844A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG054":["D405N"],"OPG120":["D111N"]},"labels":{"aa":"OPG054: D405N; OPG120: D111N"}},"children":[{"name":"OR743498","node_attrs":{"div":562,"accession":"OR743498","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1029"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-10-XX"},"strain_display":{"value":"Germany/OR743498/2023-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C45528T","C84767T","C170791T"],"OPG064":["R124K"]},"labels":{"aa":"OPG064: R124K"}}},{"name":"OR743494","node_attrs":{"div":559,"accession":"OR743494","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1025"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-09-XX"},"strain_display":{"value":"Germany/OR743494/2023-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G179263-","C179264-"]}}}]},{"name":"NODE_0000099","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C67289T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG085":["E415K"]},"labels":{"aa":"OPG085: E415K"}},"children":[{"name":"OR500079","node_attrs":{"div":562,"accession":"OR500079","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"country":{"value":"Romania"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Romania/B-16/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-04"},"strain_display":{"value":"Romania/OR500079/2022-08-04"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A31817T","G74360A","G97717T","C133109A","C166374G","T166375G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG094":["R194H"],"OPG117":["E557*"],"OPG191":["L72G"]},"labels":{"aa":"OPG094: R194H; OPG117: E557*; OPG191: L72G"}}},{"name":"NODE_0000100","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C23567T","G67527A","G77052A"]}},"children":[{"name":"OP415212","node_attrs":{"div":560,"accession":"OP415212","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPX_UbfBKN_9000238"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415212/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OP536788","node_attrs":{"div":560,"accession":"OP536788","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"9000413"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP536788/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A"]}}}]}]},{"name":"NODE_0000101","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G47746-","G49680-","G49710-","G62109-","A62110-","T62111-","A62112-","A62113-","A62114-","G62115-","A62116-","G62117-","T62118-","C62119-","C62120-","T62121-","A62122-","T62123-","A62124-","T62125-","A62126-","T62127-","T62128-","T62129-","G62130-","A62131-","A62132-","A62133-","A62134-","T62135-","C62136-","G62137-","T62138-","T62139-","A62140-","C62141-","G62142-","G62143-","T62144-","T62145-","C62146-","G62147-","A62148-","T62149-","T62150-","A62151-","C62166-","A62167-","T62168-","T62169-","G62170-","T62171-","G62172-","A62173-","A62174-","T62175-","A62176-","T62177-","A62178-","T62179-","C62180-","A62181-","T62182-","T62183-","A62184-","G62185-","G62186-","A62187-","T62188-","T62189-","T62190-","A62191-","A62192-","C62193-","T62194-","C62195-","C62196-","T62197-","T62198-","G62199-","A62200-","C62201-","T62202-","A62203-","T62204-","C62205-","A62206-","T62207-","G62208-","G62209-","C62210-","G62211-","G62212-","T62213-","G62214-","C62215-","C62216-","A62217-","G62218-","A62219-","A62220-","A62221-","T62222-","T62223-","A62224-","C62225-","C62226-","A62227-","T62228-","C62229-","A62230-","A62231-","A62232-","A62233-","G62234-","C62235-","A62236-","T62237-","T62238-","A62239-","A62240-","T62241-","A62242-","C62243-","A62244-","G62245-","T62246-","T62247-","A62248-","T62249-","G62250-","C62251-","A62252-","G62253-","A62254-","T62255-","C62256-","G62257-","C62258-","A62259-","G62260-","T62261-","T62262-","A62263-","G62264-","A62265-","A62266-","C62267-","G62268-","G62269-","T62270-","T62271-","A62272-","T62273-","A62274-","G62275-","C62276-","A62277-","T62278-","C62279-","C62280-","A62281-","C62282-","C62283-","A62284-","T62285-","T62286-","T62287-","A62288-","T62289-","A62290-","T62291-","C62292-","T62293-","A62294-","A62295-","A62296-","A62297-","A62298-","T62299-","T62300-","A62301-","G62302-","A62303-","T62304-","C62305-","A62306-","A62307-","A62308-","G62309-","A62310-","A62311-","T62312-","A62313-","T62314-","G62315-","T62316-","G62317-","A62318-","C62319-","A62320-","A62321-","C62322-","G62323-","T62324-","C62325-","C62326-","T62327-","A62328-","G62329-","T62330-","T62331-","G62332-","T62333-","A62334-","T62335-","A62336-","C62337-","T62338-","G62339-","A62340-","G62341-","A62342-","A62343-","T62344-","T62345-","G62346-","A62347-","C62348-","G62349-","A62350-","A62351-","A62352-","C62353-","A62354-","A62355-","T62356-","G62357-","T62358-","T62359-","T62360-","C62361-","T62362-","T62363-","A62364-","C62365-","A62366-","T62367-","A62368-","T62369-","T62370-","T62371-","T62372-","T62373-","T62374-","T62375-","C62376-","T62377-","T62378-","A62379-","T62380-","T62381-","A62382-","G62383-","T62384-","A62385-","A62386-","C62387-","C62388-","G62389-","A62390-","C62391-","T62392-","T62393-","A62394-","A62395-","T62396-","A62397-","G62398-","T62399-","A62400-","G62401-","G62402-","A62403-","A62404-","C62405-","T62406-","G62407-","G62408-","A62409-","A62410-","A62411-","A62412-","C62413-","T62414-","A62415-","G62416-","A62417-","C62418-","T62419-","T62420-","G62421-","A62422-","T62423-","T62424-","A62425-","T62426-","T62427-","C62428-","T62429-","A62430-","T62431-","A62432-","A62433-","G62434-","T62435-","A62436-","T62437-","A62438-","G62439-","A62440-","T62441-","A62442-","C62443-","C62444-","C62445-","T62446-","T62447-","C62448-","C62449-","A62450-","A62451-","A62452-","T62453-","A62454-","A62455-","T62456-","G62457-","T62458-","T62459-","C62460-","T62461-","C62462-","T62463-","T62464-","T62465-","G62466-","A62467-","T62468-","A62469-","A62470-","A62471-","A62472-","G62473-","T62474-","T62475-","C62476-","C62477-","A62478-","G62479-","A62480-","A62481-","A62482-","A62483-","T62484-","G62485-","T62486-","A62487-","G62488-","A62489-","A62490-","T62491-","T62492-","T62493-","T62494-","T62495-","T62496-","A62497-","A62498-","A62499-","A62500-","A62501-","G62502-","T62503-","T62504-","A62505-","T62506-","C62507-","T62508-","T62509-","T62510-","T62511-","G62512-","C62513-","T62514-","A62515-","T62516-","T62517-","A62518-","C62519-","T62520-","A62521-","A62522-","T62523-","A62524-","T62525-","C62526-","G62527-","T62528-","G62529-","G62530-","T62531-","T62532-","A62533-","G62534-","A62535-","C62536-","G62537-","C62538-","T62539-","T62540-","A62541-","T62542-","T62543-","A62544-","T62545-","T62546-","A62547-","A62548-","T62549-","A62550-","T62551-","G62552-","A62553-","G62554-","T62555-","G62556-","A62557-","T62558-","G62559-","A62560-","A62561-","A62562-","T62563-","C62564-","C62565-","A62566-","C62567-","A62568-","C62569-","C62570-","G62571-","C62572-","T62573-","T62574-","C62575-","T62576-","A62577-","G62578-","A62579-","T62580-","A62581-","T62582-","C62583-","G62584-","C62585-","T62586-","T62587-","T62588-","T62589-","A62590-","T62591-","T62592-","T62593-","C62594-","C62595-","A62596-","C62597-","A62598-","T62599-","T62600-","A62601-","G62602-","A62603-","T62604-","G62605-","G62606-","T62607-","A62608-","A62609-","A62610-","T62611-","C62612-","C62613-","A62614-","A62615-","T62616-","A62617-","G62618-","T62619-","G62620-","A62621-","A62622-","A62623-","C62624-","T62625-","A62626-","T62627-","C62628-","T62629-","T62630-","A62703-","T62704-","A62705-","A62706-","A62707-","C62708-","A62709-","A62710-","T62711-","T62712-","T62713-","C62714-","A62715-","C62716-","A62717-","A62718-","A62719-","T62720-","G62721-","G62722-","A62723-","T62724-","G62725-","T62726-","T62727-","A62728-","A62729-","T62730-","G62731-","T62732-","A62733-","T62734-","T62735-","A62736-","G62737-","T62738-","A62739-","G62740-","G62741-","A62742-","A62743-","A62744-","T62745-","T62746-","T62747-","T62748-","T62749-","T62750-","G62751-","A62752-","C62753-","G62754-","C62755-","T62756-","A62757-","G62758-","T62759-","G62760-","G62761-","A62762-","A62763-","T62764-","T62765-","G62766-","A62767-","A62768-","G62769-","A62770-","T62771-","T62772-","C62773-","T62774-","A62775-","A62776-","T62777-","G62778-","G62779-","A62780-","T62781-","G62782-","A62783-","T62784-","G62785-","T62786-","T62787-","C62788-","T62789-","A62790-","C62791-","C62792-","T62793-","A62794-","T62795-","T62796-","T62797-","C62798-","A62799-","T62800-","C62801-","C62802-","G62803-","A62804-","T62805-","A62806-","A62807-","C62808-","A62809-","T62810-","G62811-","T62812-","T62813-","A62814-","A62815-","T62816-","T62817-","T62818-","C62819-","C62820-","A62821-","A62822-","T62823-","A62824-","C62825-","C62826-","A62827-","A62828-","C62829-","G62830-","G62831-","T62832-","T62833-","T62834-","T62835-","A62836-","A62837-","T62838-","A62839-","T62840-","T62841-","T62842-","C62843-","G62844-","A62845-","T62846-","G62847-","A62848-","T62849-","A62850-","T62851-","A62852-","C62853-","G62854-","G62855-","T62856-","A62857-","G62858-","T62859-","C62860-","T62861-","C62862-","T62863-","C62864-","T62865-","T62866-","T62867-","C62868-","G62869-","G62870-","A62871-","C62872-","T62873-","T62874-","A62875-","T62876-","A62877-","T62878-","A62879-","G62880-","C62881-","T62882-","T62883-","A62884-","T62885-","T62886-","C62887-","C62888-","A62889-","C62890-","A62891-","A62892-","T62893-","A62894-","C62895-","G62896-","A62897-","G62898-","T62899-","C62900-","A62901-","T62902-","T62903-","A62904-","T62905-","A62906-","T62907-","A62908-","C62909-","T62910-","C62911-","C62912-","A62913-","A62914-","A62915-","A62916-","A62917-","A62918-","C62919-","A62920-","A62921-","A62922-","A62923-","T62924-","A62925-","A62926-","C62927-","T62928-","A62929-","G62930-","T62931-","A62932-","T62933-","A62934-","A62935-","A62936-","A62937-","T62938-","C62939-","T62940-","G62941-","T62942-","A62943-","T62944-","C62945-","G62946-","A62947-","A62948-","T62949-","G62950-","G62951-","G62952-","A62953-","A62954-","A62955-","A62956-","A62957-","C62958-","G62959-","A62960-","A62961-","A62962-","T62963-","T62964-","A62965-","T62966-","C62967-","G62968-","A62969-","T62970-","A62971-","T62972-","A62973-","G62974-","G62975-","T62976-","A62977-","T62978-","A62979-","G62980-","A62981-","A62982-","T62983-","C62984-","C62985-","G62986-","G62987-","A62988-","A62989-","C62990-","A62991-","T62992-","T62993-","G62994-","A62995-","A62996-","C62997-","G62998-","T62999-","A63000-","T63001-","T63002-","A63003-","A63004-","T63005-","A63006-","C63007-","T63008-","T63009-","A63010-","A63011-","T63012-","T63013-","C63014-","T63015-","T63016-","T63017-","T63018-","T63019-","C63020-","A63021-","G63022-","T63023-","G63024-","G63025-","T63026-","A63027-","A63028-","G63029-","A63030-","A63031-","C63032-","C63033-","G63034-","A63035-","T63036-","A63037-","G63038-","G63039-","T63040-","T63041-","A63042-","T63043-","T63044-","G63045-","A63046-","C63047-","A63048-","T63049-","T63050-","G63051-","T63052-","A63053-","T63054-","G63055-","G63056-","T63057-","T63058-","T63059-","T63060-","A63061-","A63062-","A63063-","T63064-","A63065-","T63066-","T63067-","C63068-","T63069-","A63070-","T63071-","A63072-","A63073-","C63074-","T63075-","T63076-","G63077-","A63078-","G63079-","A63080-","C63081-","T63082-","T63083-","G63084-","A63085-","T63086-","A63087-","G63088-","A63089-","T63090-","A63091-","T63092-","T63093-","A63094-","A63095-","T63096-","G63097-","A63098-","C63099-","G63100-","A63101-","A63102-","T63103-","T63104-","G63105-","A63106-","A63107-","A63108-","A63109-","T63110-","T63111-","A63112-","T63113-","T63114-","T63115-","T63116-","T63117-","A63118-","T63119-","C63120-","A63121-","C63122-","C63123-","A63124-","C63125-","G63126-","T63127-","G63128-","T63129-","G63130-","T63131-","T63132-","T63133-","C63134-","A63135-","G63136-","G63137-","A63138-","T63139-","C63140-","A63141-","T63142-","C63143-","G63144-","T63145-","C63146-","G63147-","A63148-","C63149-","G63150-","C63151-","C63152-","A63153-","G63154-","T63155-","T63156-","A63157-","A63158-","C63159-","C63160-","A63161-","A63162-","C63163-","C63164-","G63165-","A63166-","A63167-","T63168-","G63169-","G63170-","A63171-","G63172-","T63173-","A63174-","A63175-","A63176-","A63177-","T63178-","A63179-","A63180-","A63181-","T63182-","A63183-","T63184-","C63185-","A63186-","T63187-","T63188-","A63189-","A63190-","T63191-","A63192-","T63193-","A63194-","T63195-","G63196-","C63197-","T63198-","C63199-","T63200-","A63201-","G63202-","A63203-","T63204-","A63205-","T63206-","T63207-","A63208-","G63209-","T63210-","A63211-","T63212-","T63213-","T63214-","T63215-","T63216-","A63217-","T63218-","T63219-","A63220-","A63221-","T63222-","C63223-","C63224-","T63225-","T63226-","T63227-","G63228-","A63229-","T63230-","T63231-","A63232-","T63233-","C63234-","A63235-","T63236-","C63237-","T63238-","T63239-","C63240-","T63241-","C63242-","G63243-","T63244-","A63245-","C63246-","G63247-","C63248-","G63249-","A63250-","A63251-","T63252-","G63253-","A63254-","T63255-","T63256-","C63257-","C63258-","A63259-","T63260-","G63261-","A63262-","T63263-","C63264-","A63265-","A63266-","G63267-","A63268-","G63269-","T63270-","G63271-","A63272-","T63273-","T63274-","T63275-","G63276-","A63277-","G63278-","A63279-","A63280-","C63281-","A63282-","T63283-","C63284-","C63285-","T63286-","C63287-","C63288-","G63289-","G63290-","A63291-","G63292-","T63293-","A63294-","T63295-","T63296-","A63297-","A63298-","T63299-","G63300-","G63301-","G63302-","T63303-","T63304-","T63305-","A63306-","G63307-","T63308-","A63309-","A63310-","A63311-","C63312-","A63313-","G63314-","T63315-","C63316-","C63317-","A63318-","T63319-","C63320-","G63321-","T63322-","T63323-","G63324-","C63325-","A63326-","A63327-","T63328-","A63329-","A63330-","T63331-","A63332-","A63333-","A63334-","A63335-","G63336-","T63337-","T63338-","G63339-","T63340-","C63341-","C63342-","A63343-","A63344-","G63345-","T63346-","T63347-","A63348-","A63349-","A63350-","G63351-","G63352-","A63353-","T63354-","A63355-","T63356-","T63357-","A63358-","T63359-","G63360-","C63361-","A63362-","T63363-","T63364-","C63365-","G63366-","T63367-","T63368-","T63369-","A63370-","A63371-","A63372-","G63373-","A63374-","T63375-","A63376-","T63377-","C63378-","A63379-","C63380-","C63381-","T63382-","C63383-","A63384-","T63385-","C63386-","T63387-","A63388-","A63389-","C63390-","G63391-","G63392-","A63393-","G63394-","A63395-","C63396-","A63397-","A63398-","T63399-","T63400-","T63401-","T63402-","T63403-","T63404-","G63405-","G63406-","T63407-","A63408-","G63409-","G63410-","T63411-","T63412-","T63413-","T63414-","A63415-","G63416-","A63417-","G63418-","A63419-","C63420-","T63421-","T63422-","T63423-","G63424-","A63425-","A63426-","G63427-","C63428-","T63429-","A63430-","C63431-","T63432-","T63433-","G63434-","T63435-","T63436-","T63437-","A63438-","A63439-","C63440-","A63441-","A63442-","A63443-","G63444-","T63445-","T63446-","A63447-","T63448-","T63449-","C63450-","A63451-","T63452-","C63453-","G63454-","T63455-","C63456-","G63457-","T63458-","C63459-","T63460-","A63461-","C63462-","T63463-","A63464-","T63465-","T63466-","C63467-","T63468-","A63469-","T63470-","T63471-","T63472-","A63473-","A63474-","T63475-","T63476-","T63477-","T63478-","G63479-","T63480-","A63481-","G63482-","T63483-","T63484-","A63485-","A63486-","T63487-","T63488-","T63489-","A63490-","T63491-","C63492-","A63493-","C63494-","A63495-","T63496-","A63497-","T63498-","C63499-","A63500-","C63501-","A63502-","T63503-","T63504-","C89166T","C112408T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG131":["L157F"]},"labels":{"aa":"OPG131: L157F"}},"children":[{"name":"OQ672570","node_attrs":{"div":558,"accession":"OQ672570","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"02112022_anal"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-02"},"strain_display":{"value":"Belgium/OQ672570/2022-11-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"OPG068":["D494-"],"OPG081":["N46-","R47-","T48-","V49-","T50-","I51-","F52-","K53-","Y54-","I55-","G56-","L57-","F58-","I59-"]},"labels":{"aa":"OPG068: D494-; OPG081: N46-, R47-, T48-, V49-, T50-, I51-, F52-, K53-, Y54-, I55-, G56-, L57-, F58-, I59-"}}},{"name":"NODE_0000102","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","G187391A","A194549-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-"],"OPG002":["R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-","C47-"],"OPG002_dup":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-"]},"labels":{"aa":"OPG002: R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-, C47-; OPG002_dup: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-"}},"children":[{"name":"OQ672572","node_attrs":{"div":559,"accession":"OQ672572","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"26012023_anal"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-26"},"strain_display":{"value":"Belgium/OQ672572/2023-01-26"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-47746G","-49680G","-49710G","-62109G","-62110A","-62111T","-62112A","-62113A","-62114A","-62115G","-62116A","-62117G","-62118T","-62119C","-62120C","-62121T","-62122A","-62123T","-62124A","-62125T","-62126A","-62127T","-62128T","-62129T","-62130G","-62131A","-62132A","-62133A","-62134A","-62135T","-62136C","-62137G","-62138T","-62139T","-62140A","-62141C","-62142G","-62143G","-62144T","-62145T","-62146C","-62147G","-62148A","-62149T","-62150T","-62151A","-62166C","-62167A","-62168T","-62169T","-62170G","-62171T","-62172G","-62173A","-62174A","-62175T","-62176A","-62177T","-62178A","-62179T","-62180C","-62181A","-62182T","-62183T","-62184A","-62185G","-62186G","-62187A","-62188T","-62189T","-62190T","-62191A","-62192A","-62193C","-62194T","-62195C","-62196C","-62197T","-62198T","-62199G","-62200A","-62201C","-62202T","-62203A","-62204T","-62205C","-62206A","-62207T","-62208G","-62209G","-62210C","-62211G","-62212G","-62213T","-62214G","-62215C","-62216C","-62217A","-62218G","-62219A","-62220A","-62221A","-62222T","-62223T","-62224A","-62225C","-62226C","-62227A","-62228T","-62229C","-62230A","-62231A","-62232A","-62233A","-62234G","-62235C","-62236A","-62237T","-62238T","-62239A","-62240A","-62241T","-62242A","-62243C","-62244A","-62245G","-62246T","-62247T","-62248A","-62249T","-62250G","-62251C","-62252A","-62253G","-62254A","-62255T","-62256C","-62257G","-62258C","-62259A","-62260G","-62261T","-62262T","-62263A","-62264G","-62265A","-62266A","-62267C","-62268G","-62269G","-62270T","-62271T","-62272A","-62273T","-62274A","-62275G","-62276C","-62277A","-62278T","-62279C","-62280C","-62281A","-62282C","-62283C","-62284A","-62285T","-62286T","-62287T","-62288A","-62289T","-62290A","-62291T","-62292C","-62293T","-62294A","-62295A","-62296A","-62297A","-62298A","-62299T","-62300T","-62301A","-62302G","-62303A","-62304T","-62305C","-62306A","-62307A","-62308A","-62309G","-62310A","-62311A","-62312T","-62313A","-62314T","-62315G","-62316T","-62317G","-62318A","-62319C","-62320A","-62321A","-62322C","-62323G","-62324T","-62325C","-62326C","-62327T","-62328A","-62329G","-62330T","-62331T","-62332G","-62333T","-62334A","-62335T","-62336A","-62337C","-62338T","-62339G","-62340A","-62341G","-62342A","-62343A","-62344T","-62345T","-62346G","-62347A","-62348C","-62349G","-62350A","-62351A","-62352A","-62353C","-62354A","-62355A","-62356T","-62357G","-62358T","-62359T","-62360T","-62361C","-62362T","-62363T","-62364A","-62365C","-62366A","-62367T","-62368A","-62369T","-62370T","-62371T","-62372T","-62373T","-62374T","-62375T","-62376C","-62377T","-62378T","-62379A","-62380T","-62381T","-62382A","-62383G","-62384T","-62385A","-62386A","-62387C","-62388C","-62389G","-62390A","-62391C","-62392T","-62393T","-62394A","-62395A","-62396T","-62397A","-62398G","-62399T","-62400A","-62401G","-62402G","-62403A","-62404A","-62405C","-62406T","-62407G","-62408G","-62409A","-62410A","-62411A","-62412A","-62413C","-62414T","-62415A","-62416G","-62417A","-62418C","-62419T","-62420T","-62421G","-62422A","-62423T","-62424T","-62425A","-62426T","-62427T","-62428C","-62429T","-62430A","-62431T","-62432A","-62433A","-62434G","-62435T","-62436A","-62437T","-62438A","-62439G","-62440A","-62441T","-62442A","-62443C","-62444C","-62445C","-62446T","-62447T","-62448C","-62449C","-62450A","-62451A","-62452A","-62453T","-62454A","-62455A","-62456T","-62457G","-62458T","-62459T","-62460C","-62461T","-62462C","-62463T","-62464T","-62465T","-62466G","-62467A","-62468T","-62469A","-62470A","-62471A","-62472A","-62473G","-62474T","-62475T","-62476C","-62477C","-62478A","-62479G","-62480A","-62481A","-62482A","-62483A","-62484T","-62485G","-62486T","-62487A","-62488G","-62489A","-62490A","-62491T","-62492T","-62493T","-62494T","-62495T","-62496T","-62497A","-62498A","-62499A","-62500A","-62501A","-62502G","-62503T","-62504T","-62505A","-62506T","-62507C","-62508T","-62509T","-62510T","-62511T","-62512G","-62513C","-62514T","-62515A","-62516T","-62517T","-62518A","-62519C","-62520T","-62521A","-62522A","-62523T","-62524A","-62525T","-62526C","-62527G","-62528T","-62529G","-62530G","-62531T","-62532T","-62533A","-62534G","-62535A","-62536C","-62537G","-62538C","-62539T","-62540T","-62541A","-62542T","-62543T","-62544A","-62545T","-62546T","-62547A","-62548A","-62549T","-62550A","-62551T","-62552G","-62553A","-62554G","-62555T","-62556G","-62557A","-62558T","-62559G","-62560A","-62561A","-62562A","-62563T","-62564C","-62565C","-62566A","-62567C","-62568A","-62569C","-62570C","-62571G","-62572C","-62573T","-62574T","-62575C","-62576T","-62577A","-62578G","-62579A","-62580T","-62581A","-62582T","-62583C","-62584G","-62585C","-62586T","-62587T","-62588T","-62589T","-62590A","-62591T","-62592T","-62593T","-62594C","-62595C","-62596A","-62597C","-62598A","-62599T","-62600T","-62601A","-62602G","-62603A","-62604T","-62605G","-62606G","-62607T","-62608A","-62609A","-62610A","-62611T","-62612C","-62613C","-62614A","-62615A","-62616T","-62617A","-62618G","-62619T","-62620G","-62621A","-62622A","-62623A","-62624C","-62625T","-62626A","-62627T","-62628C","-62629T","-62630T","-62703A","-62704T","-62705A","-62706A","-62707A","-62708C","-62709A","-62710A","-62711T","-62712T","-62713T","-62714C","-62715A","-62716C","-62717A","-62718A","-62719A","-62720T","-62721G","-62722G","-62723A","-62724T","-62725G","-62726T","-62727T","-62728A","-62729A","-62730T","-62731G","-62732T","-62733A","-62734T","-62735T","-62736A","-62737G","-62738T","-62739A","-62740G","-62741G","-62742A","-62743A","-62744A","-62745T","-62746T","-62747T","-62748T","-62749T","-62750T","-62751G","-62752A","-62753C","-62754G","-62755C","-62756T","-62757A","-62758G","-62759T","-62760G","-62761G","-62762A","-62763A","-62764T","-62765T","-62766G","-62767A","-62768A","-62769G","-62770A","-62771T","-62772T","-62773C","-62774T","-62775A","-62776A","-62777T","-62778G","-62779G","-62780A","-62781T","-62782G","-62783A","-62784T","-62785G","-62786T","-62787T","-62788C","-62789T","-62790A","-62791C","-62792C","-62793T","-62794A","-62795T","-62796T","-62797T","-62798C","-62799A","-62800T","-62801C","-62802C","-62803G","-62804A","-62805T","-62806A","-62807A","-62808C","-62809A","-62810T","-62811G","-62812T","-62813T","-62814A","-62815A","-62816T","-62817T","-62818T","-62819C","-62820C","-62821A","-62822A","-62823T","-62824A","-62825C","-62826C","-62827A","-62828A","-62829C","-62830G","-62831G","-62832T","-62833T","-62834T","-62835T","-62836A","-62837A","-62838T","-62839A","-62840T","-62841T","-62842T","-62843C","-62844G","-62845A","-62846T","-62847G","-62848A","-62849T","-62850A","-62851T","-62852A","-62853C","-62854G","-62855G","-62856T","-62857A","-62858G","-62859T","-62860C","-62861T","-62862C","-62863T","-62864C","-62865T","-62866T","-62867T","-62868C","-62869G","-62870G","-62871A","-62872C","-62873T","-62874T","-62875A","-62876T","-62877A","-62878T","-62879A","-62880G","-62881C","-62882T","-62883T","-62884A","-62885T","-62886T","-62887C","-62888C","-62889A","-62890C","-62891A","-62892A","-62893T","-62894A","-62895C","-62896G","-62897A","-62898G","-62899T","-62900C","-62901A","-62902T","-62903T","-62904A","-62905T","-62906A","-62907T","-62908A","-62909C","-62910T","-62911C","-62912C","-62913A","-62914A","-62915A","-62916A","-62917A","-62918A","-62919C","-62920A","-62921A","-62922A","-62923A","-62924T","-62925A","-62926A","-62927C","-62928T","-62929A","-62930G","-62931T","-62932A","-62933T","-62934A","-62935A","-62936A","-62937A","-62938T","-62939C","-62940T","-62941G","-62942T","-62943A","-62944T","-62945C","-62946G","-62947A","-62948A","-62949T","-62950G","-62951G","-62952G","-62953A","-62954A","-62955A","-62956A","-62957A","-62958C","-62959G","-62960A","-62961A","-62962A","-62963T","-62964T","-62965A","-62966T","-62967C","-62968G","-62969A","-62970T","-62971A","-62972T","-62973A","-62974G","-62975G","-62976T","-62977A","-62978T","-62979A","-62980G","-62981A","-62982A","-62983T","-62984C","-62985C","-62986G","-62987G","-62988A","-62989A","-62990C","-62991A","-62992T","-62993T","-62994G","-62995A","-62996A","-62997C","-62998G","-62999T","-63000A","-63001T","-63002T","-63003A","-63004A","-63005T","-63006A","-63007C","-63008T","-63009T","-63010A","-63011A","-63012T","-63013T","-63014C","-63015T","-63016T","-63017T","-63018T","-63019T","-63020C","-63021A","-63022G","-63023T","-63024G","-63025G","-63026T","-63027A","-63028A","-63029G","-63030A","-63031A","-63032C","-63033C","-63034G","-63035A","-63036T","-63037A","-63038G","-63039G","-63040T","-63041T","-63042A","-63043T","-63044T","-63045G","-63046A","-63047C","-63048A","-63049T","-63050T","-63051G","-63052T","-63053A","-63054T","-63055G","-63056G","-63057T","-63058T","-63059T","-63060T","-63061A","-63062A","-63063A","-63064T","-63065A","-63066T","-63067T","-63068C","-63069T","-63070A","-63071T","-63072A","-63073A","-63074C","-63075T","-63076T","-63077G","-63078A","-63079G","-63080A","-63081C","-63082T","-63083T","-63084G","-63085A","-63086T","-63087A","-63088G","-63089A","-63090T","-63091A","-63092T","-63093T","-63094A","-63095A","-63096T","-63097G","-63098A","-63099C","-63100G","-63101A","-63102A","-63103T","-63104T","-63105G","-63106A","-63107A","-63108A","-63109A","-63110T","-63111T","-63112A","-63113T","-63114T","-63115T","-63116T","-63117T","-63118A","-63119T","-63120C","-63121A","-63122C","-63123C","-63124A","-63125C","-63126G","-63127T","-63128G","-63129T","-63130G","-63131T","-63132T","-63133T","-63134C","-63135A","-63136G","-63137G","-63138A","-63139T","-63140C","-63141A","-63142T","-63143C","-63144G","-63145T","-63146C","-63147G","-63148A","-63149C","-63150G","-63151C","-63152C","-63153A","-63154G","-63155T","-63156T","-63157A","-63158A","-63159C","-63160C","-63161A","-63162A","-63163C","-63164C","-63165G","-63166A","-63167A","-63168T","-63169G","-63170G","-63171A","-63172G","-63173T","-63174A","-63175A","-63176A","-63177A","-63178T","-63179A","-63180A","-63181A","-63182T","-63183A","-63184T","-63185C","-63186A","-63187T","-63188T","-63189A","-63190A","-63191T","-63192A","-63193T","-63194A","-63195T","-63196G","-63197C","-63198T","-63199C","-63200T","-63201A","-63202G","-63203A","-63204T","-63205A","-63206T","-63207T","-63208A","-63209G","-63210T","-63211A","-63212T","-63213T","-63214T","-63215T","-63216T","-63217A","-63218T","-63219T","-63220A","-63221A","-63222T","-63223C","-63224C","-63225T","-63226T","-63227T","-63228G","-63229A","-63230T","-63231T","-63232A","-63233T","-63234C","-63235A","-63236T","-63237C","-63238T","-63239T","-63240C","-63241T","-63242C","-63243G","-63244T","-63245A","-63246C","-63247G","-63248C","-63249G","-63250A","-63251A","-63252T","-63253G","-63254A","-63255T","-63256T","-63257C","-63258C","-63259A","-63260T","-63261G","-63262A","-63263T","-63264C","-63265A","-63266A","-63267G","-63268A","-63269G","-63270T","-63271G","-63272A","-63273T","-63274T","-63275T","-63276G","-63277A","-63278G","-63279A","-63280A","-63281C","-63282A","-63283T","-63284C","-63285C","-63286T","-63287C","-63288C","-63289G","-63290G","-63291A","-63292G","-63293T","-63294A","-63295T","-63296T","-63297A","-63298A","-63299T","-63300G","-63301G","-63302G","-63303T","-63304T","-63305T","-63306A","-63307G","-63308T","-63309A","-63310A","-63311A","-63312C","-63313A","-63314G","-63315T","-63316C","-63317C","-63318A","-63319T","-63320C","-63321G","-63322T","-63323T","-63324G","-63325C","-63326A","-63327A","-63328T","-63329A","-63330A","-63331T","-63332A","-63333A","-63334A","-63335A","-63336G","-63337T","-63338T","-63339G","-63340T","-63341C","-63342C","-63343A","-63344A","-63345G","-63346T","-63347T","-63348A","-63349A","-63350A","-63351G","-63352G","-63353A","-63354T","-63355A","-63356T","-63357T","-63358A","-63359T","-63360G","-63361C","-63362A","-63363T","-63364T","-63365C","-63366G","-63367T","-63368T","-63369T","-63370A","-63371A","-63372A","-63373G","-63374A","-63375T","-63376A","-63377T","-63378C","-63379A","-63380C","-63381C","-63382T","-63383C","-63384A","-63385T","-63386C","-63387T","-63388A","-63389A","-63390C","-63391G","-63392G","-63393A","-63394G","-63395A","-63396C","-63397A","-63398A","-63399T","-63400T","-63401T","-63402T","-63403T","-63404T","-63405G","-63406G","-63407T","-63408A","-63409G","-63410G","-63411T","-63412T","-63413T","-63414T","-63415A","-63416G","-63417A","-63418G","-63419A","-63420C","-63421T","-63422T","-63423T","-63424G","-63425A","-63426A","-63427G","-63428C","-63429T","-63430A","-63431C","-63432T","-63433T","-63434G","-63435T","-63436T","-63437T","-63438A","-63439A","-63440C","-63441A","-63442A","-63443A","-63444G","-63445T","-63446T","-63447A","-63448T","-63449T","-63450C","-63451A","-63452T","-63453C","-63454G","-63455T","-63456C","-63457G","-63458T","-63459C","-63460T","-63461A","-63462C","-63463T","-63464A","-63465T","-63466T","-63467C","-63468T","-63469A","-63470T","-63471T","-63472T","-63473A","-63474A","-63475T","-63476T","-63477T","-63478T","-63479G","-63480T","-63481A","-63482G","-63483T","-63484T","-63485A","-63486A","-63487T","-63488T","-63489T","-63490A","-63491T","-63492C","-63493A","-63494C","-63495A","-63496T","-63497A","-63498T","-63499C","-63500A","-63501C","-63502A","-63503T","-63504T"]}}},{"name":"OQ672578","node_attrs":{"div":563,"accession":"OQ672578","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"23022023_anal"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-23"},"strain_display":{"value":"Belgium/OQ672578/2023-02-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A2611-","C2612-","A2613-","C2614-","G2615-","A2616-","T2617-","A2618-","G2619-","A2620-","C2621-","A2622-","T2653-","T2654-","T2655-","A2656-","C2657-","A2658-","C2659-","T2660-","T2661-","T2662-","C8201T","T39397C","C47694-","T47695-","C47696-","A47697-","T47698-","T47699-","A47700-","C47701-","G47702-","A47703-","G47704-","A47705-","C47706-","A47707-","T47708-","T47709-","G47710-","A47711-","A47712-","A47713-","C47714-","T47715-","A47716-","G47717-","G47718-","A47719-","T47720-","A47721-","T47722-","A47723-","T47724-","A47725-","A47726-","A47727-","A47728-","T47729-","T47730-","T47731-","A47732-","A47733-","G47734-","G47735-","G47736-","A47737-","A47738-","T47739-","G47740-","A47741-","T47742-","T47743-","A47744-","G47745-","A47747-","C47748-","T47749-","A47750-","C47751-","T47752-","A47753-","C47754-","T47755-","C47756-","T47757-","A47758-","G47759-","A47760-","A47761-","G47762-","A47763-","T47764-","A47765-","T47766-","A47767-","G47768-","C47769-","A47770-","C47771-","C47772-","A47773-","T47774-","C47775-","T47776-","A47777-","T47778-","T47779-","C47780-","C47781-","A47782-","A47783-","A47784-","T47785-","A47786-","A47787-","T47788-","C47789-","A47790-","G47791-","A47792-","A47793-","A47794-","A47795-","C47796-","T47797-","T47798-","A47799-","T47800-","A47801-","A47802-","A47803-","C47804-","T47805-","A47806-","T47807-","T47808-","C47809-","T47810-","C47811-","G47812-","G47813-","A47814-","C47815-","A47816-","T47817-","T47818-","T47819-","C47820-","A47821-","G47822-","T47823-","C47824-","A47825-","T47826-","T47827-","G47828-","G47829-","C47830-","A47831-","A47832-","A47833-","G47834-","C47835-","A47836-","T47837-","C47838-","A47839-","C47840-","A47841-","G47842-","A47843-","A47844-","T47845-","C47846-","C47847-","G47848-","A47849-","G47850-","T47851-","A47852-","A47853-","G47854-","A47855-","T47856-","G47857-","A47858-","T47859-","A47860-","T47861-","A47862-","T47863-","G47864-","C47865-","T47866-","C47867-","G47868-","C47869-","T47870-","G47871-","C47872-","T47873-","T47874-","T47875-","A47876-","C47877-","A47878-","T47879-","G47880-","T47881-","T47882-","T47883-","C47884-","C47885-","C47886-","A47887-","A47888-","T47889-","T47890-","T47891-","G47892-","T47893-","T47894-","T47895-","G47896-","G47897-","A47898-","G47899-","A47900-","T47901-","G47902-","A47903-","C47904-","C47905-","A47906-","T47907-","A47908-","G47909-","A47910-","T47911-","T47912-","C47913-","A47914-","T47915-","T47916-","T47917-","G47918-","T47919-","T47920-","A47921-","T47922-","A47923-","G47924-","A47925-","A47926-","T47927-","G47928-","C47929-","A47930-","T47931-","C47932-","C47933-","A47934-","A47935-","C47936-","A47937-","T47938-","T47939-","G47940-","T47941-","T47942-","C47943-","A47944-","T47945-","G47946-","A47947-","T47948-","A47949-","T47950-","A47951-","G47952-","T47953-","T47954-","G47955-","A47956-","A47957-","T47958-","C47959-","A47960-","T47961-","G47962-","T47963-","A47964-","T47965-","G47966-","C47967-","C47968-","T47969-","G47970-","T47971-","T47972-","C47973-","G47974-","T47975-","A47976-","T47977-","G47978-","C47979-","C47980-","T47981-","G47982-","T47983-","G47984-","G47985-","C47986-","T47987-","A47988-","A47989-","G47990-","A47991-","T47992-","A47993-","C47994-","T47995-","G47996-","T47997-","G47998-","T47999-","A48000-","A48001-","A48002-","G48003-","A48004-","A48005-","A48006-","T48007-","G48008-","G48009-","T48010-","A48011-","A48012-","A48013-","T48014-","A48015-","A48016-","A48017-","T48018-","A48019-","C48020-","T48021-","T48022-","T48023-","G48024-","A48025-","G48026-","A48027-","A48028-","T48029-","C48030-","T48031-","T48032-","T48033-","A48034-","A48035-","G48036-","A48037-","G48038-","T48039-","G48040-","C48041-","A48042-","T48043-","T48044-","G48045-","A48046-","C48047-","T48048-","T48049-","T48050-","G48051-","T48052-","T48053-","A48054-","G48055-","T48056-","G48057-","A48058-","A48059-","T48060-","A48061-","G48062-","G48063-","C48064-","A48065-","T48066-","T48067-","C48068-","C48069-","A48070-","T48071-","C48072-","T48073-","T48074-","T48075-","C48076-","T48077-","C48078-","C48079-","A48080-","A48081-","T48082-","A48083-","C48084-","T48085-","A48086-","A48087-","T48088-","T48089-","C48090-","A48091-","A48092-","A48093-","T48094-","T48095-","G48096-","T48097-","T48098-","A48099-","A48100-","A48101-","T48102-","T48103-","A48104-","A48105-","T48106-","A48107-","A48108-","T48109-","G48110-","G48111-","A48112-","A48113-","T48114-","A48115-","G48116-","T48117-","A48118-","T48119-","A48120-","A48121-","A48122-","T48123-","A48124-","G48125-","T48126-","T48127-","A48128-","T48129-","T48130-","A48131-","G48132-","T48133-","G48134-","A48135-","T48136-","A48137-","G48138-","G48139-","A48140-","T48141-","A48142-","G48143-","T48144-","A48145-","A48146-","A48147-","C48148-","A48149-","T48150-","A48151-","A48152-","T48153-","T48154-","A48155-","T48156-","T48157-","A48158-","G48159-","A48160-","A48161-","T48162-","A48163-","G48164-","T48165-","A48166-","G48167-","T48168-","G48169-","T48170-","A48171-","G48172-","T48173-","A48174-","T48175-","C48176-","A48177-","T48178-","A48179-","G48180-","A48181-","T48182-","A48183-","A48184-","C48185-","T48186-","C48187-","T48188-","C48189-","T48190-","T48191-","C48192-","T48193-","A48194-","T48195-","A48196-","A48197-","A48198-","A48199-","A48200-","A48201-","T48202-","G48203-","G48204-","A48205-","T48206-","T48207-","T48208-","T48209-","A48210-","T48211-","T48212-","C48213-","G48214-","T48215-","A48216-","G48217-","A48218-","A48219-","A48220-","G48221-","T48222-","A48223-","T48224-","C48225-","T48226-","T48227-","A48228-","T48229-","A48230-","T48231-","A48232-","C48233-","A48234-","C48235-","A48236-","G48237-","T48238-","A48239-","G48240-","A48241-","A48242-","A48243-","A48244-","T48245-","A48246-","A48247-","T48248-","A48249-","T48250-","A48251-","G48252-","A48253-","T48254-","T48255-","T48256-","T48257-","T48258-","T48259-","A48260-","A48261-","A48262-","G48263-","G48264-","A48265-","T48266-","G48267-","A48268-","T48269-","A48270-","C48271-","A48272-","T48273-","T48274-","A48275-","A48276-","G48277-","T48278-","A48279-","A48280-","A48281-","G48282-","T48283-","A48284-","A48285-","A48286-","C48287-","A48288-","A48289-","T48290-","T48291-","T48292-","T48293-","A48294-","C48295-","C48296-","C48297-","T48298-","C48299-","A48300-","A48301-","T48302-","C48303-","A48304-","T48305-","G48306-","T48307-","A48308-","C48309-","T48310-","A48311-","G48312-","C48313-","T48314-","C48315-","T48316-","C48317-","A48318-","A48319-","G48320-","T48321-","A48322-","T48323-","C48324-","T48325-","A48326-","G48327-","T48328-","T48329-","A48330-","G48331-","C48332-","A48333-","A48334-","T48335-","T48336-","T48337-","T48338-","C48339-","C48340-","T48341-","C48342-","A48343-","A48344-","C48345-","A48346-","T48347-","G48348-","T48349-","T48350-","A48351-","T48352-","T48353-","A48354-","C48355-","T48356-","A48357-","A48358-","G48359-","G48360-","A48361-","T48362-","G48363-","T48364-","A48365-","T48366-","T48367-","A48368-","G48369-","C48370-","T48371-","A48372-","A48373-","T48374-","A48375-","C48376-","C48377-","A48378-","A48379-","T48380-","T48381-","T48382-","T48383-","T48384-","T48385-","T48386-","G48387-","T48388-","T48389-","T48390-","T48391-","C48392-","A48393-","T48394-","A48395-","C48396-","A48397-","T48398-","A48399-","T48400-","G48401-","G48402-","T48403-","A48404-","C48405-","G48406-","A48407-","T48408-","G48409-","C48410-","T48411-","G48412-","T48413-","A48414-","A48415-","A48416-","G48417-","T48418-","A48419-","T48420-","A48421-","C48422-","G48423-","A48424-","A48425-","G48426-","C48427-","G48428-","G48429-","T48430-","T48431-","T48432-","T48433-","A48434-","C48435-","G48436-","A48437-","C48438-","A48439-","C48440-","G48441-","C48442-","A48443-","T48444-","T48445-","T48446-","G48447-","A48448-","T48449-","G48450-","C48451-","A48452-","C48453-","C48454-","C48455-","A48456-","C48457-","G48458-","T48459-","T48460-","G48461-","T48462-","A48463-","C48464-","G48465-","T48466-","T48467-","A48468-","A48469-","A48470-","G48471-","C48472-","A48473-","T48474-","T48475-","G48476-","A48477-","C48478-","T48479-","A48480-","A48481-","G48482-","A48483-","A48484-","T48485-","T48486-","A48487-","T48488-","T48489-","T48490-","A48491-","T48492-","C48493-","G48494-","T48495-","T48496-","T48497-","A48498-","G48499-","T48500-","A48501-","A48502-","C48503-","A48504-","C48505-","A48506-","A48507-","T48508-","A48509-","C48510-","A48511-","G48512-","T48513-","C48514-","G48515-","T48516-","A48517-","C48518-","A48519-","A48520-","G48521-","G48522-","A48523-","A48524-","A48525-","C48526-","A48527-","G48528-","T48529-","G48530-","C48531-","A48532-","T48533-","A48534-","A48535-","A48536-","C48537-","T48538-","A48539-","A48540-","C48541-","A48542-","C48543-","A48544-","A48545-","G48546-","A48547-","T48548-","G48549-","A48550-","A48551-","A48552-","A48553-","A48554-","T48555-","T48556-","T48557-","T48558-","T48559-","A48560-","G48561-","A48562-","G48563-","G48564-","T48565-","T48566-","G48567-","C48568-","C48569-","G48570-","A48571-","A48572-","T48573-","A48574-","C48575-","A48576-","T48577-","G48578-","G48579-","A48580-","C48581-","G48582-","A48583-","A48584-","T48585-","T48586-","A48587-","G48588-","G48589-","A48590-","G48591-","A48592-","A48593-","C48594-","T48595-","T48596-","A48597-","T48598-","A48599-","G48600-","G48601-","C48602-","G48603-","T48604-","A48605-","A48606-","A48607-","T48608-","T48609-","A48610-","T48611-","G48612-","A48613-","C48614-","T48615-","T48616-","A48617-","G48618-","T48619-","T48620-","C48621-","T48622-","T48623-","A48624-","A48625-","T48626-","C48627-","C48628-","A48629-","T48630-","T48631-","A48632-","T48633-","T48634-","T48635-","C48636-","A48637-","C48638-","G48639-","G48640-","A48641-","G48642-","G48643-","G48644-","G48645-","A48646-","A48647-","C48648-","C48649-","C48650-","A48651-","T48652-","C48653-","A48654-","A48655-","A48656-","G48657-","A48658-","T48659-","A48660-","T48661-","G48662-","G48663-","A48664-","A48665-","A48666-","T48667-","C48668-","A48669-","T48670-","T48671-","T48672-","T48673-","T48674-","T48675-","T48676-","A48677-","A48678-","A48679-","A48680-","C48681-","T48682-","G48683-","T48684-","T48685-","T48686-","A48687-","A48688-","G48689-","A48690-","A48691-","A48692-","A48693-","C48694-","A48695-","G48696-","A48697-","C48698-","T48699-","T48700-","C48701-","A48702-","A48703-","A48704-","G48705-","T48706-","T48707-","G48708-","T48709-","T48710-","A48711-","A48712-","A48713-","A48714-","A48715-","A48716-","T48717-","T48718-","A48719-","A48720-","G48721-","T48722-","G48723-","T48724-","T48725-","A48726-","T48727-","A48728-","A48729-","G48730-","A48731-","T48732-","T48733-","A48734-","C48735-","T48736-","T48737-","A48738-","T48739-","T48740-","T48741-","G48742-","G48743-","G48744-","C48745-","A48746-","T48747-","A48748-","C48749-","C48750-","T48751-","A48752-","A48753-","G48754-","C48755-","A48756-","A48757-","G48758-","A48759-","A48760-","A48761-","G48762-","A48763-","T48764-","A48765-","C48766-","A48767-","G48768-","G48769-","C48770-","A48771-","T48772-","A48773-","G48774-","A48775-","G48776-","T48777-","T48778-","T48779-","G48780-","C48781-","G48782-","G48783-","A48784-","T48785-","A48786-","A48787-","T48788-","G48789-","A48790-","T48791-","A48792-","G48793-","A48794-","C48795-","A48796-","A48797-","G48798-","A48799-","T48800-","A48801-","T48802-","A48803-","T48804-","A48805-","T48806-","A48807-","C48808-","T48809-","C48810-","T48811-","A48812-","T48813-","T48814-","T48815-","C48816-","A48817-","A48818-","C48819-","A48820-","A48821-","A48822-","C48823-","T48824-","G48825-","G48826-","T48827-","A48828-","G48829-","A48830-","A48831-","T48832-","A48833-","G48834-","T48835-","C48836-","C48837-","A48838-","T48839-","A48840-","G48841-","C48842-","A48843-","A48844-","T48845-","C48846-","T48847-","A48848-","A48849-","C48850-","A48851-","G48852-","A48853-","A48854-","A48855-","C48856-","G48857-","T48858-","T48859-","T48860-","A48861-","G48862-","G48863-","G48864-","A48865-","T48866-","T48867-","A48868-","T48869-","A48870-","T48871-","C48872-","T48873-","T48874-","T48875-","C48876-","C48877-","C48878-","G48879-","G48880-","A48881-","G48882-","A48883-","T48884-","A48885-","A48886-","G48887-","A48888-","C48889-","T48890-","A48891-","G48892-","C48893-","T48894-","A48895-","T48896-","T48897-","G48898-","G48899-","G48900-","T48901-","G48902-","T48903-","G48904-","G48905-","T48906-","T48907-","A48908-","A48909-","A48910-","C48911-","G48912-","A48913-","A48914-","A48915-","G48916-","T48917-","A48918-","T48919-","A48920-","G48921-","C48922-","T48923-","A48924-","A48925-","T48926-","G48927-","A48928-","T48929-","G48930-","C48931-","G48932-","G48933-","A48934-","T48935-","A48936-","T48937-","C48938-","G48939-","T48940-","T48941-","A48942-","T48943-","T48944-","A48945-","A48946-","T48947-","A48948-","G48949-","A48950-","C48951-","C48952-","C48953-","G48954-","C48955-","C48956-","A48957-","T48958-","T48959-","A48960-","C48961-","C48962-","A48963-","T48964-","G48965-","T48966-","A48967-","T48968-","G48969-","A48970-","T48971-","A48972-","A48973-","A48974-","A48975-","T48976-","T48977-","C48978-","T48979-","T48980-","A48981-","G48982-","T48983-","T48984-","A48985-","T48986-","A48987-","T48988-","A48989-","T48990-","A48991-","C48992-","T48993-","C48994-","T48995-","G48996-","A48997-","G48998-","A48999-","T49000-","A49001-","A49002-","A49003-","A49004-","C49005-","A49006-","G49007-","G49008-","G49009-","A49010-","C49011-","G49012-","C49013-","G49014-","T49015-","T49016-","A49017-","A49018-","T49019-","A49020-","A49021-","A49022-","A49023-","A49024-","C49025-","A49026-","T49027-","G49028-","C49029-","T49030-","T49031-","A49032-","A49033-","G49034-","T49035-","T49036-","A49037-","G49038-","T49039-","T49040-","T49041-","A49042-","T49043-","A49044-","T49045-","C49046-","T49047-","T49048-","T49049-","G49050-","A49051-","G49052-","C49053-","C49054-","T49055-","G49056-","A49057-","A49058-","A49059-","A49060-","A49061-","G49062-","A49063-","T49064-","A49065-","T49066-","C49067-","A49068-","G49069-","A49070-","G49071-","A49072-","A49073-","C49074-","T49075-","T49076-","C49077-","T49078-","G49079-","C49080-","T49081-","A49082-","G49083-","A49084-","A49085-","A49086-","T49087-","C49088-","A49089-","T49090-","A49091-","T49092-","A49093-","T49094-","G49095-","A49096-","T49097-","A49098-","T49099-","T49100-","C49101-","C49102-","T49103-","G49104-","G49105-","A49106-","G49107-","A49108-","T49109-","A49110-","T49111-","C49112-","C49113-","T49114-","A49115-","T49116-","C49117-","T49118-","A49119-","T49120-","T49121-","A49122-","T49123-","T49124-","G49125-","A49126-","T49127-","G49128-","C49129-","A49130-","A49131-","A49132-","A49133-","A49134-","A49135-","C49136-","G49137-","A49138-","C49139-","G49140-","A49141-","T49142-","T49143-","G49144-","G49145-","A49146-","A49147-","A49148-","A49149-","A49150-","A49151-","T49152-","A49153-","T49154-","T49155-","T49156-","T49157-","A49158-","T49159-","T49160-","A49161-","G49162-","T49163-","T49164-","T49165-","T49166-","T49167-","A49168-","C49169-","A49170-","A49171-","A49172-","G49173-","C49174-","T49175-","A49176-","A49177-","T49178-","T49179-","T49180-","T49181-","A49182-","T49183-","T49184-","A49185-","A49186-","C49187-","G49188-","G49189-","T49190-","A49191-","A49192-","T49193-","A49194-","C49195-","A49196-","T49197-","T49198-","T49199-","A49200-","T49201-","T49202-","A49203-","G49204-","T49205-","G49206-","A49207-","T49208-","A49209-","G49210-","A49211-","A49212-","C49213-","G49214-","T49215-","T49216-","T49217-","A49218-","A49219-","C49220-","G49221-","A49222-","T49223-","G49224-","A49225-","C49226-","T49227-","T49228-","A49229-","T49230-","T49231-","C49232-","A49233-","G49234-","A49235-","G49236-","T49237-","T49238-","G49239-","T49240-","T49241-","G49242-","T49243-","T49244-","C49245-","A49246-","A49247-","A49248-","T49249-","A49250-","G49251-","A49252-","T49253-","C49254-","C49255-","C49256-","G49257-","A49258-","A49259-","T49260-","A49261-","T49262-","T49263-","T49264-","C49265-","G49266-","A49267-","T49268-","A49269-","A49270-","T49271-","G49272-","A49273-","A49274-","C49275-","G49276-","A49277-","A49278-","T49279-","T49280-","A49281-","T49282-","G49283-","T49284-","C49285-","T49286-","T49287-","T49288-","A49289-","T49290-","T49291-","C49292-","T49293-","A49294-","T49295-","A49296-","C49297-","G49298-","A49299-","G49300-","T49301-","G49302-","C49303-","T49304-","G49305-","C49306-","G49307-","G49308-","A49309-","C49310-","A49311-","T49312-","T49313-","A49314-","A49315-","A49316-","C49317-","G49318-","A49319-","T49320-","T49321-","T49322-","G49323-","A49324-","T49325-","G49326-","A49327-","G49328-","T49329-","T49330-","A49331-","G49332-","A49333-","T49334-","A49335-","T49336-","T49337-","A49338-","A49339-","T49340-","A49341-","A49342-","C49343-","A49344-","G49345-","T49346-","T49347-","A49348-","T49349-","A49350-","T49351-","A49352-","T49353-","C49354-","T49355-","A49356-","A49357-","T49358-","A49359-","T49360-","A49361-","A49362-","T49363-","T49364-","T49365-","A49366-","T49367-","G49368-","A49369-","G49370-","G49371-","T49372-","G49373-","A49374-","A49375-","C49376-","G49377-","A49378-","T49379-","A49380-","T49381-","C49382-","A49383-","C49384-","A49385-","T49386-","T49387-","A49388-","G49389-","A49390-","T49391-","A49392-","C49393-","A49394-","A49395-","T49396-","G49397-","G49398-","A49399-","T49400-","G49401-","A49402-","T49403-","A49404-","T49405-","G49406-","A49407-","A49408-","G49409-","A49410-","A49411-","G49412-","T49413-","G49414-","T49415-","C49416-","A49417-","A49418-","A49419-","T49420-","C49421-","T49422-","T49423-","T49424-","A49425-","A49426-","C49427-","G49428-","A49429-","G49430-","G49431-","A49432-","T49433-","A49434-","C49435-","G49436-","T49437-","T49438-","G49439-","T49440-","A49441-","T49442-","T49443-","A49444-","T49445-","G49446-","T49447-","T49448-","A49449-","A49450-","G49451-","G49452-","A49453-","A49454-","T49455-","A49456-","C49457-","A49458-","A49459-","T49460-","A49461-","C49462-","A49463-","T49464-","A49465-","C49466-","C49467-","T49468-","G49469-","T49470-","T49471-","T49472-","T49473-","T49474-","G49475-","C49476-","A49477-","C49478-","G49479-","A49480-","G49481-","T49482-","C49483-","G49484-","G49485-","A49486-","T49487-","C49488-","C49489-","C49490-","A49491-","T49492-","G49493-","G49494-","T49495-","C49496-","A49497-","T49498-","A49499-","G49500-","A49501-","G49502-","A49503-","A49504-","C49505-","G49506-","G49507-","A49508-","A49509-","T49510-","A49511-","C49512-","T49513-","A49514-","A49515-","A49516-","G49517-","A49518-","A49519-","A49520-","C49521-","T49522-","G49523-","T49524-","C49525-","A49526-","T49527-","C49528-","T49529-","A49530-","T49531-","A49532-","A49533-","A49534-","A49535-","T49536-","C49537-","C49538-","A49539-","A49540-","G49541-","A49542-","G49543-","T49544-","A49545-","G49546-","A49547-","C49548-","G49549-","G49550-","C49551-","T49552-","G49553-","A49554-","A49555-","C49556-","T49557-","T49558-","G49559-","T49560-","T49561-","T49562-","A49563-","G49564-","C49565-","A49566-","A49567-","A49568-","A49569-","A49570-","C49571-","A49572-","T49573-","T49574-","T49575-","T49576-","A49577-","A49578-","A49579-","A49580-","T49581-","A49582-","T49583-","T49584-","A49585-","T49586-","T49587-","T49588-","A49589-","G49590-","A49591-","C49592-","G49593-","G49594-","A49595-","C49596-","A49597-","A49598-","T49599-","T49600-","G49601-","G49602-","C49603-","T49604-","C49605-","G49606-","T49607-","C49608-","T49609-","A49610-","G49611-","G49612-","T49613-","C49614-","T49615-","T49616-","G49617-","T49618-","G49619-","T49620-","T49621-","A49622-","G49623-","A49624-","T49625-","G49626-","A49627-","T49628-","T49629-","A49630-","T49631-","A49632-","A49633-","A49634-","G49635-","G49636-","A49637-","G49638-","A49639-","C49640-","T49641-","T49642-","A49643-","T49644-","T49645-","A49646-","G49647-","T49648-","T49649-","A49650-","A49651-","A49652-","A49653-","T49654-","G49655-","A49656-","T49657-","A49658-","A49659-","A49660-","C49661-","C49662-","A49663-","T49664-","C49665-","T49666-","C49667-","A49668-","A49669-","A49670-","T49671-","C49672-","T49673-","G49674-","T49675-","G49676-","G49677-","A49678-","G49679-","A49681-","T49682-","G49683-","T49684-","A49685-","T49686-","C49687-","C49688-","G49689-","C49690-","A49691-","T49692-","T49693-","C49694-","G49695-","T49696-","T49697-","A49698-","G49699-","A49700-","T49701-","T49702-","T49703-","T49704-","C49705-","T49706-","A49707-","C49708-","A49709-","A49711-","T49712-","G61626-","A61627-","G61628-","C61629-","T61630-","T61631-","A61674-","A61675-","T61676-","C61677-","G61678-","G61679-","A61680-","G61681-","A61682-","A61683-","T61684-","G61685-","T61686-","T61687-","T61688-","C61689-","C61690-","C61691-","A61692-","T61693-","T61694-","T61695-","T61696-","T61697-","A61698-","G61699-","G61700-","A61701-","T61702-","T61703-","A61704-","A61705-","C61706-","A61707-","T61708-","A61709-","G61710-","T61740-","A61741-","G61742-","T61743-","T61744-","A61764-","T61765-","T61766-","T61767-","G61768-","A61769-","T61770-","A61771-","A61791-","A61792-","T61793-","G61794-","G61795-","C61796-","A61797-","T61798-","A61799-","A61800-","T61801-","C61802-","C61803-","G61804-","G61805-","A61806-","T61807-","G61808-","T61809-","T61810-","G61811-","T61812-","G61813-","T61814-","A61815-","G61816-","T61817-","A61818-","C61819-","A61820-","A61821-","G61822-","T61823-","G61824-","G61825-","C61826-","T61827-","G61828-","C61829-","T61830-","A61831-","T61832-","T61833-","T61834-","C61835-","G61836-","G61837-","C61838-","T61839-","G61840-","C61841-","C61842-","A61843-","G61844-","A61845-","G61846-","T61847-","G61848-","T61849-","C61850-","C61851-","A61852-","A61853-","T61854-","T61855-","C61856-","T61857-","A61858-","C61859-","C61860-","G61861-","T61862-","T61863-","G61864-","T61865-","T61866-","A61867-","C61868-","T61869-","C61870-","C61871-","A61872-","T61873-","T61874-","A61875-","T61876-","A61877-","T61878-","A61879-","T61880-","T61881-","C61882-","C61883-","T61884-","T61885-","G61886-","A61887-","A61888-","T61889-","A61890-","A61891-","C61892-","C61893-","T61894-","T61895-","C61896-","A61897-","T61898-","A61899-","G61900-","C61901-","T61902-","A61903-","T61904-","T61905-","T61906-","T61907-","A61908-","A61909-","T61910-","A61911-","G61912-","G61913-","A61914-","T61915-","C61916-","T61917-","A61918-","T61919-","A61920-","T61921-","G61922-","A61923-","T61924-","C61925-","A61926-","G61927-","T61928-","G61929-","T61930-","T61931-","T61932-","A61933-","A61934-","G61935-","C61936-","C61937-","A61938-","T61939-","A61940-","G61941-","C61942-","A61943-","C61944-","A61945-","A61946-","T61947-","T61948-","T61949-","T61950-","C61951-","T61952-","A61953-","A61954-","T61955-","A61956-","C61957-","G61958-","A61959-","G61960-","A61961-","C61962-","G61963-","T61964-","G61965-","A61966-","T61967-","T61968-","T61969-","T61970-","A61971-","T61972-","C61973-","A61974-","A61975-","A61976-","C61977-","A61978-","T61979-","G61980-","A61981-","C61982-","A61983-","T61984-","T61985-","T61986-","T61987-","C61988-","C61989-","T61990-","T61991-","G61992-","T61993-","A61994-","T61995-","C61996-","C61997-","A61998-","T61999-","T62000-","T62001-","C62002-","G62003-","T62004-","T62005-","T62006-","A62007-","A62008-","T62009-","G62010-","A62011-","C62012-","A62013-","A62014-","A62015-","C62016-","A62017-","T62018-","T62019-","T62020-","T62021-","T62022-","G62023-","T62024-","T62025-","G62026-","G62027-","T62028-","G62029-","T62030-","A62031-","A62032-","T62033-","A62034-","A62035-","A62036-","A62037-","A62038-","A62039-","A62040-","A62041-","T62042-","T62043-","A62044-","T62045-","T62046-","T62047-","A62048-","A62049-","T62050-","T62051-","T62052-","T62053-","T62054-","C62055-","A62056-","T62057-","T62058-","A62059-","A62060-","T62061-","A62062-","G62063-","G62064-","G62065-","A62066-","T62067-","T62068-","T62069-","G62070-","A62071-","C62072-","G62073-","T62074-","A62075-","T62076-","G62077-","T62078-","A62079-","G62080-","C62081-","G62082-","T62083-","A62084-","C62085-","A62086-","A62087-","A62088-","A62089-","T62090-","T62091-","A62092-","T62093-","C62094-","G62095-","T62096-","T62097-","C62098-","C62099-","T62100-","G62101-","G62102-","T62103-","A62104-","T62105-","A62106-","T62107-","A62108-","A62152-","A62153-","C62154-","T62155-","T62156-","T62157-","A62158-","A62159-","T62160-","G62161-","A62162-","T62163-","T62164-","G62165-","T62631-","T62632-","T62633-","A62634-","G62635-","G62636-","A62637-","A62638-","T62639-","G62640-","T62641-","A62642-","T62643-","G62644-","G62645-","A62646-","C62647-","T62648-","C62649-","G62650-","C62651-","G62652-","T62653-","T62654-","T62655-","A62656-","G62657-","A62658-","G62659-","G62660-","A62661-","G62662-","T62663-","G62664-","A62665-","A62666-","C62667-","G62668-","T62669-","C62670-","T62671-","T62672-","C62673-","G62674-","G62675-","A62676-","G62677-","T62678-","A62679-","G62680-","T62681-","A62682-","A62683-","A62684-","G62685-","G62686-","A62687-","T62688-","G62689-","A62690-","T62691-","T62692-","C62693-","G62694-","T62695-","C62696-","A62697-","A62698-","A62699-","T62700-","G62701-","A62702-","A63505-","A63506-","G88521-","A88522-","T88523-","C88524-","T88525-","C88526-","T88527-","A88528-","T88529-","A88530-","A88531-","T88532-","A88533-","T88534-","C88535-","T88536-","A88537-","G88538-","T88539-","T88540-","T88541-","C88542-","T88543-","T88544-","G88545-","C88546-","G88547-","T88548-","T88549-","T88550-","C88551-","A88552-","C88553-","A88554-","A88555-","A88556-","C88557-","A88558-","C88559-","A88560-","G88561-","G88562-","C88563-","T88564-","C88565-","G88566-","T88567-","C88568-","T88569-","C88570-","T88571-","C88572-","G88573-","C88574-","G88575-","A88576-","T88577-","G88578-","A88579-","G88580-","A88581-","T88582-","C88583-","T88584-","G88585-","T88586-","A88587-","T88588-","A88589-","G88590-","T88591-","A88592-","A88593-","C88594-","T88595-","A88596-","T88597-","G88598-","T88599-","A88600-","A88601-","A88602-","T88603-","G88604-","A88605-","T88606-","A88607-","A88608-","C88609-","T88610-","A88611-","G88612-","A88613-","T88614-","A88615-","G88616-","A88617-","A88618-","A88619-","G88620-","A88621-","T88622-","G88623-","T88624-","A88625-","G88626-","C88627-","T88628-","A88629-","T88630-","A88631-","T88632-","A88633-","G88634-","A88635-","T88636-","G88637-","A88638-","C88639-","G88640-","A88641-","T88642-","C88643-","C88644-","T88645-","T88646-","T88647-","A88648-","A88649-","G88650-","A88651-","G88652-","A88653-","G88654-","G88655-","T88656-","A88657-","T88658-","A88659-","A88660-","T88661-","A88662-","A88663-","C88664-","T88665-","T88666-","T88667-","A88668-","C88669-","C88670-","C88671-","C88672-","A88673-","A88674-","T88675-","C88676-","A88677-","G88678-","A88679-","T88680-","A88681-","G88682-","A88683-","C88684-","T88685-","G88686-","T88687-","T88688-","G88689-","T88690-","T88691-","A88692-","T88693-","G88694-","G88695-","T88696-","C88697-","T88698-","T88699-","C88700-","G88701-","G88702-","A88703-","A88704-","A88705-","A88706-","A88707-","G88708-","A88709-","A88710-","T88711-","T88712-","T88713-","T88714-","T88715-","A88716-","T88717-","A88718-","A88719-","A88720-","T88721-","T88722-","T88723-","T88724-","T88725-","C88726-","C88727-","A88728-","G88729-","T88730-","A88731-","T88732-","T88733-","T88734-","T88735-","C88736-","T88737-","A88738-","A88739-","A88740-","T88741-","A88742-","T88743-","A88744-","C88745-","G88746-","T88747-","A88748-","C88749-","T88750-","T88751-","G88752-","A88753-","T88754-","A88755-","T88756-","C88757-","T88758-","A88759-","A88760-","G88761-","A88762-","A88763-","A88764-","T88765-","C88766-","C88767-","T88768-","T88769-","A88770-","A88771-","T88772-","A88773-","A88774-","T88775-","A88776-","A88777-","T88778-","A88779-","G88780-","G88781-","A88782-","A88783-","T88784-","G88785-","G88786-","A88787-","T88788-","A88789-","A88790-","T88791-","C88792-","C88793-","G88794-","T88795-","C88796-","T88797-","A88798-","T88799-","T88800-","T88801-","T88802-","A88803-","T88804-","A88805-","A88806-","A88807-","G88808-","A88809-","A88810-","A88811-","T88812-","A88813-","C88814-","A88815-","T88816-","A88817-","T88818-","C88819-","G88820-","C88821-","A88822-","T88823-","A88824-","T88825-","T88826-","A88827-","T88828-","A88829-","C88830-","T88831-","T88832-","T88833-","T88834-","T88835-","T88836-","T88837-","T88838-","G88839-","G88840-","A88841-","A88842-","A88843-","T88844-","T88845-","G88846-","G88847-","A88848-","A88849-","T88850-","A88851-","C88852-","C88853-","G88854-","A88855-","T88856-","G88857-","T88858-","G88859-","T88860-","C88861-","T88862-","A88863-","C88864-","A88865-","T88866-","A88867-","A88868-","A88869-","T88870-","A88871-","C88872-","G88873-","C88874-","A88875-","A88876-","A88877-","G88878-","T88879-","C88880-","T88881-","A88882-","A88883-","A88884-","T88885-","A88886-","T88887-","T88888-","T88889-","T88890-","T88891-","T88892-","A88893-","G88894-","A88895-","G88896-","A88897-","A88898-","T88899-","C88900-","T88901-","T88902-","A88903-","G88904-","T88905-","T88906-","G88907-","G88908-","T88909-","C88910-","C88911-","A88912-","A88913-","A88914-","T88915-","T88916-","C88917-","T88918-","T88919-","T88920-","T88921-","C88922-","C88923-","A88924-","A88925-","G88926-","T88927-","A88928-","C88929-","G88930-","G88931-","T88932-","A88933-","A88934-","T88935-","A88936-","G88937-","A88938-","T88939-","T88940-","T88941-","T88942-","T88943-","C88944-","A88945-","T88946-","A88947-","T88948-","T88949-","G88950-","A88951-","A88952-","C88953-","G88954-","G88955-","T88956-","A88957-","T88958-","C88959-","T88960-","T88961-","C88962-","T88963-","T88964-","G88965-","A88966-","T88967-","C88968-","T88969-","C88970-","T88971-","G88972-","G88973-","T88974-","T88975-","C88976-","T88977-","A88978-","A88979-","T88980-","T88981-","C88982-","C88983-","G88984-","C88985-","A88986-","T88987-","T88988-","A88989-","A88990-","A88991-","T88992-","G88993-","A88994-","T88995-","G88996-","A88997-","A88998-","A88999-","C89000-","T89001-","A89002-","A89003-","G89004-","T89005-","C89006-","A89007-","C89008-","T89009-","A89010-","T89011-","T89012-","T89013-","T89014-","T89015-","A89016-","T89017-","A89018-","A89019-","C89020-","T89021-","A89022-","A89023-","C89024-","G89025-","A89026-","T89027-","T89028-","A89029-","C89030-","A89031-","T89032-","C89033-","A89034-","C89035-","C89036-","T89037-","C89038-","T89039-","A89040-","A89041-","C89042-","A89043-","T89044-","C89045-","A89046-","T89047-","C89048-","A89049-","T89050-","T89051-","T89052-","A89053-","C89054-","C89055-","A89056-","G89057-","G89058-","A89059-","T89060-","A89061-","C89062-","T89063-","G89064-","A89065-","T89066-","C89067-","T89068-","T89069-","C89070-","T89071-","T89072-","T89073-","T89074-","G89075-","T89076-","C89077-","G89078-","T89079-","A89080-","A89081-","A89082-","T89083-","A89084-","C89085-","A89086-","T89087-","G89088-","T89089-","C89090-","T89091-","A89092-","A89093-","T89094-","G89095-","T89096-","G89097-","T89098-","T89099-","A89100-","A89101-","A89102-","A89103-","A89104-","A89105-","A89106-","A89107-","G89108-","A89109-","T89110-","C89111-","A89112-","T89113-","A89114-","C89115-","A89116-","A89117-","G89118-","T89119-","T89120-","A89121-","T89122-","A89123-","C89124-","G89125-","T89126-","C89127-","A89128-","T89129-","T89130-","T89131-","C89132-","A89133-","T89134-","C89135-","T89136-","G89137-","T89138-","A89139-","G89140-","T89141-","A89142-","T89143-","T89144-","C89145-","T89146-","T89147-","G89148-","T89149-","C89150-","A89151-","T89152-","T89153-","G89154-","A89155-","A89156-","G89157-","G89158-","A89159-","T89160-","A89161-","A89162-","A89163-","C89164-","T89165-","T89166-","G89167-","T89168-","A89169-","C89170-","T89171-","A89172-","A89173-","T89174-","C89175-","T89176-","C89177-","T89178-","T89179-","C89180-","T89181-","T89182-","T89183-","A89184-","A89185-","C89186-","A89187-","G89188-","T89189-","C89190-","T89191-","G89192-","T89193-","T89194-","C89195-","A89196-","A89197-","A89198-","T89199-","T89200-","T89201-","A89202-","T89203-","A89204-","T89205-","C89206-","C89207-","T89208-","A89209-","T89210-","A89211-","T89212-","A89213-","T89214-","G89215-","A89216-","A89217-","A89218-","A89219-","A89220-","A89221-","T89222-","A89223-","G89224-","C89225-","A89226-","A89227-","C89228-","C89229-","A89230-","G89231-","T89232-","G89233-","T89234-","T89235-","T89236-","G89237-","A89238-","T89239-","C89240-","A89241-","T89242-","C89243-","C89244-","G89245-","C89246-","G89247-","T89248-","C89249-","A89250-","A89251-","T89252-","A89253-","T89254-","T89255-","C89256-","T89257-","G89258-","T89259-","T89260-","C89261-","T89262-","A89263-","T89264-","C89265-","G89266-","T89267-","A89268-","G89269-","T89270-","G89271-","T89272-","A89273-","T89274-","A89275-","A89276-","C89277-","A89278-","A89279-","T89280-","C89281-","T89282-","T89283-","A89284-","T89285-","A89286-","T89287-","C89288-","T89289-","T89290-","C89291-","T89292-","T89293-","C89294-","T89295-","G89296-","T89297-","G89298-","A89299-","T89300-","A89301-","G89302-","T89303-","C89304-","G89305-","A89306-","T89307-","A89308-","C89309-","G89310-","T89311-","T89312-","A89313-","T89314-","A89315-","A89316-","A89317-","G89318-","G89319-","T89320-","T89321-","G89322-","A89323-","T89324-","A89325-","A89326-","C89327-","G89328-","A89329-","A89330-","A89331-","A89332-","T89333-","A89334-","T89335-","T89336-","T89337-","T89338-","T89339-","A89340-","T89341-","T89342-","T89343-","C89344-","G89345-","T89346-","G89347-","A89348-","A89349-","A89350-","T89351-","A89352-","A89353-","A89354-","G89355-","T89356-","C89357-","A89358-","T89359-","T89360-","G89361-","T89362-","A89363-","G89364-","G89365-","A89366-","T89367-","T89368-","T89369-","T89370-","G89371-","G89372-","A89373-","C89374-","T89375-","T89376-","A89377-","T89378-","A89379-","T89380-","T89381-","C89382-","G89383-","T89384-","G89385-","T89386-","C89387-","T89388-","A89389-","G89390-","T89391-","A89392-","G89393-","A89394-","T89395-","A89396-","T89397-","G89398-","A89399-","T89400-","T89401-","T89402-","T89403-","A89404-","T89405-","T89406-","T89407-","T89408-","T89409-","G89410-","G89411-","A89412-","A89413-","T89414-","G89415-","A89416-","T89417-","C89418-","T89419-","C89420-","A89421-","A89422-","T89423-","T89424-","A89425-","A89426-","A89427-","A89428-","T89429-","A89430-","G89431-","T89432-","C89433-","T89434-","C89435-","T89436-","T89437-","T89438-","A89439-","G89440-","A89441-","G89442-","T89443-","C89444-","C89445-","A89446-","T89447-","T89448-","T89449-","A89450-","A89451-","A89452-","G89453-","T89454-","T89455-","A89456-","C89457-","A89458-","A89459-","A89460-","C89461-","A89462-","A89463-","C89464-","T89465-","A89466-","G89467-","G89468-","A89469-","A89470-","A89471-","T89472-","T89473-","G89474-","G89475-","T89476-","T89477-","T89478-","A89479-","T89480-","G89481-","A89482-","T89483-","G89484-","T89485-","A89486-","T89487-","A89488-","A89489-","T89490-","T89491-","T89492-","T89493-","T89494-","T89495-","T89496-","A89497-","G89498-","T89499-","T89500-","T89501-","T89502-","T89503-","A89504-","T89505-","A89506-","G89507-","A89508-","T89509-","T89510-","C89511-","T89512-","T89513-","T89514-","A89515-","T89516-","T89517-","C89518-","T89519-","A89520-","T89521-","A89522-","C89523-","T89524-","T89525-","A89526-","A89527-","A89528-","A89529-","A89530-","A89531-","T89532-","G89533-","A89534-","A89535-","A89536-","A89537-","T89538-","A89539-","A89540-","A89541-","T89542-","A89543-","C89544-","A89545-","A89546-","A89547-","G89548-","G89549-","T89550-","T89551-","C89552-","T89553-","T89554-","G89555-","A89556-","G89557-","G89558-","G89559-","T89560-","T89561-","G89562-","T89563-","G89564-","T89565-","T89566-","A89567-","A89568-","T89569-","T89570-","G89571-","A89572-","A89573-","A89574-","G89575-","C89576-","G89577-","A89578-","T89579-","A89580-","A89581-","A89582-","T89583-","A89584-","A89585-","T89586-","C89587-","A89588-","T89589-","A89590-","A89591-","A89592-","T89593-","T89594-","A89595-","T89596-","T89597-","T89598-","C89599-","A89600-","T89601-","T89602-","A89603-","T89604-","C89605-","G89606-","C89607-","G89608-","A89609-","T89610-","A89611-","T89612-","C89613-","C89614-","G89615-","T89616-","T89617-","A89618-","A89619-","G89620-","T89621-","T89622-","T89623-","G89624-","T89625-","A89626-","T89627-","C89628-","G89629-","T89630-","A89631-","A89632-","T89633-","G89634-","G89635-","C89636-","G89637-","T89638-","G89639-","G89640-","T89641-","C89642-","A89643-","A89644-","T89645-","T89646-","A89647-","C89648-","G89649-","A89650-","A89651-","T89652-","A89653-","A89654-","A89655-","G89656-","C89657-","G89658-","G89659-","A89660-","T89661-","A89662-","C89663-","T89664-","A89665-","G89666-","T89667-","A89668-","G89669-","T89670-","T89671-","T89672-","C89673-","A89674-","C89675-","A89676-","A89677-","A89678-","G89679-","A89680-","T89681-","G89682-","G89683-","C89684-","T89685-","G89686-","A89687-","A89688-","A89689-","T89690-","C89691-","A89692-","G89693-","A89694-","G89695-","C89696-","T89697-","C89698-","A89699-","T89700-","C89701-","T89702-","A89703-","A89704-","G89705-","A89706-","A89707-","A89708-","T89709-","A89710-","G89711-","C89712-","G89713-","C89714-","T89715-","G89716-","A89717-","A89718-","A89719-","A89720-","T89721-","A89722-","A89723-","A89724-","G89725-","A89726-","T89727-","A89728-","A89729-","A89730-","A89731-","A89732-","C89733-","G89734-","A89735-","G89736-","G89737-","A89738-","T89739-","A89740-","T89741-","T89742-","T89743-","T89744-","C89745-","C89746-","C89747-","G89748-","G89749-","A89750-","A89751-","G89752-","A89753-","T89754-","G89755-","T89756-","A89757-","A89758-","T89759-","A89760-","A89761-","T89762-","T89763-","C89764-","C89765-","A89766-","T89767-","C89768-","T89769-","A89770-","C89771-","T89772-","A89773-","A89774-","G89775-","C89776-","C89777-","C89778-","A89779-","A89780-","A89781-","A89782-","C89783-","C89784-","A89785-","A89786-","A89787-","C89788-","G89789-","A89790-","A89791-","C89792-","C89793-","A89794-","C89795-","T89796-","A89797-","C89798-","T89799-","C89800-","C89801-","T89802-","C89803-","G89804-","T89805-","A89806-","A89807-","A89808-","C89809-","C89810-","A89811-","G89812-","C89813-","G89814-","G89815-","C89816-","T89817-","A89818-","C89819-","T89820-","A89821-","A89822-","A89823-","A89824-","G89825-","A89826-","T89827-","C89828-","A89829-","A89830-","C89831-","C89832-","A89833-","A89834-","A89835-","A89836-","A89837-","G89838-","G89839-","A89840-","T89841-","A89842-","A89843-","A89844-","G89845-","A89846-","A89847-","A89848-","A89849-","G89850-","G89851-","A89852-","G89853-","G89854-","A89855-","A89856-","G89857-","T89858-","G89859-","G89860-","A89861-","A89862-","G89863-","A89864-","A89865-","G89866-","T89867-","A89868-","G89869-","T89870-","T89871-","A89872-","T89873-","A89874-","G89875-","A89876-","G89877-","G89878-","A89879-","A89880-","T89881-","A89882-","T89883-","C89884-","A89885-","T89886-","C89887-","A89888-","A89889-","A89890-","C89891-","A89892-","A89893-","C89894-","T89895-","G89896-","A89897-","A89898-","G89899-","A89900-","A89901-","A89902-","A89903-","T89904-","T89905-","C89906-","T89907-","C89908-","C89909-","A89910-","C89911-","C89912-","T89913-","C89914-","C89915-","G89916-","T89917-","C89918-","A89919-","T89920-","C89921-","A89922-","T89923-","C89924-","T89925-","C89926-","C89927-","T89928-","G89929-","G89930-","A89931-","G89932-","T89933-","C89934-","G89935-","G89936-","C89937-","G89938-","A89939-","C89940-","A89941-","T89942-","T89943-","G89944-","T89945-","A89946-","G89947-","A89948-","A89949-","A89950-","G89951-","C89952-","G89953-","T89954-","G89955-","G89956-","C89957-","C89958-","G89959-","C89960-","T89961-","G89962-","T89963-","A89964-","G89965-","A89966-","G89967-","C89968-","T89969-","C89970-","G89971-","A89972-","T89973-","G89974-","A89975-","T89976-","A89977-","G89978-","C89979-","G89980-","A89981-","C89982-","G89983-","G89984-","G89985-","G89986-","A89987-","T89988-","G89989-","A89990-","T89991-","G89992-","A89993-","A89994-","C89995-","C89996-","T89997-","A89998-","T89999-","G90000-","G90001-","T90002-","A90003-","C90004-","A90005-","A90006-","G90007-","T90008-","T90009-","G90010-","A90011-","A90012-","G90013-","C90014-","T90015-","G90016-","G90017-","T90018-","A90019-","A90020-","A90021-","G90022-","T90023-","A90024-","A90025-","A90026-","T90027-","C90028-","A90029-","T90030-","A90031-","G90032-","T90033-","G90034-","C90035-","T90036-","A90037-","G90038-","A90039-","A90040-","G90041-","C90042-","G90043-","A90044-","T90045-","C90046-","T90047-","C90048-","T90049-","C90050-","T90051-","G90052-","A90053-","C90054-","C90055-","T90056-","A90057-","A90058-","A90059-","G90060-","G90061-","T90062-","G90063-","G90064-","C90065-","T90066-","A90067-","C90068-","C90069-","G90070-","A90071-","C90072-","A90073-","A90074-","T90075-","A90076-","T90077-","C90078-","G90079-","T90080-","T90081-","A90082-","A90083-","A90084-","G90085-","A90086-","T90087-","C90088-","T90089-","T90090-","A90091-","A90092-","G90093-","A90094-","A90095-","A90096-","A90097-","T90098-","T90099-","A90100-","T90101-","T90102-","A90103-","C90104-","T90105-","A90106-","G90107-","A90108-","A90109-","T90110-","C90111-","T90112-","C90113-","T90114-","G90115-","C90116-","A90117-","G90118-","T90119-","A90120-","T90121-","C90122-","G90123-","A90124-","C90125-","T90126-","G90127-","T90128-","T90129-","C90130-","T90131-","A90132-","G90133-","A90134-","G90135-","G90136-","A90137-","T90138-","G90139-","T90140-","T90141-","C90142-","A90143-","A90144-","G90145-","C90146-","A90147-","G90148-","C90149-","T90150-","G90151-","G90152-","T90153-","A90154-","T90155-","C90156-","T90157-","C90158-","T90159-","A90160-","G90161-","A90162-","C90163-","A90164-","A90165-","T90166-","T90167-","T90168-","A90169-","C90170-","T90171-","T90172-","C90173-","T90174-","A90175-","T90176-","G90177-","A90178-","C90179-","T90180-","A90181-","A90182-","A90183-","G90184-","C90185-","T90186-","A90187-","T90188-","T90189-","A90190-","C90191-","A90192-","A90193-","C90194-","A90195-","C90196-","T90197-","A90198-","T90199-","C90200-","T90201-","G90202-","A90203-","T90204-","C90205-","T90206-","A90207-","G90208-","T90209-","C90210-","A90211-","C90212-","C90213-","G90214-","A90215-","G90216-","G90217-","G90218-","A90219-","A90220-","A90221-","A90222-","T90223-","C90224-","T90225-","A90226-","A90227-","A90228-","G90229-","T90230-","T90231-","G90232-","T90233-","T90234-","C90235-","G90236-","T90237-","A90238-","A90239-","A90240-","A90241-","A90242-","A90243-","G90244-","T90245-","T90246-","A90247-","A90248-","A90249-","A90250-","C90251-","T90252-","T90253-","G90254-","T90255-","A90256-","A90257-","G90258-","A90259-","A90260-","G90261-","T90262-","A90263-","A90264-","A90265-","T90266-","G90267-","C90268-","G90269-","T90270-","G90271-","C90272-","A90273-","C90274-","T90275-","T90276-","T90277-","T90278-","T90279-","T90280-","A90281-","T90282-","A90283-","A90284-","A90285-","G90286-","A90287-","T90288-","G90289-","G90290-","T90291-","A90292-","A90293-","A90294-","C90295-","T90296-","G90297-","T90298-","T90299-","T90300-","A90301-","C90302-","C90303-","G90304-","A90305-","T90306-","A90307-","A90308-","T90309-","A90310-","A90311-","T90312-","T90313-","T90314-","T90315-","T90316-","T90317-","A90318-","A90319-","A90320-","T90321-","C90322-","C90323-","T90324-","G90325-","T90326-","A90327-","T90328-","C90329-","A90330-","G90331-","A90332-","C90333-","G90334-","A90335-","T90336-","A90337-","A90338-","T90339-","C90340-","C90341-","A90342-","G90343-","C90344-","G90345-","T90346-","A90347-","T90348-","G90349-","A90350-","G90351-","G90352-","T90353-","T90354-","T90355-","T90356-","G90357-","C90358-","A90359-","A90360-","C90361-","A90362-","T90363-","G90364-","T90365-","T90366-","A90367-","A90368-","A90369-","A90370-","T90371-","T90372-","C90373-","C90374-","T90375-","A90376-","C90377-","T90378-","C90379-","A90380-","T90381-","T90382-","T90383-","A90384-","A90385-","C90386-","A90387-","G90388-","A90389-","T90390-","G90391-","T90392-","A90393-","G90394-","T90395-","A90396-","G90397-","T90398-","A90399-","T90400-","A90401-","T90402-","G90403-","A90404-","A90405-","C90406-","A90407-","A90408-","A90409-","C90410-","G90411-","T90412-","G90413-","G90414-","G90415-","A90416-","A90417-","G90418-","A90419-","G90420-","G90421-","C90422-","A90423-","T90424-","T90425-","A90426-","A90427-","C90428-","T90429-","A90430-","G90431-","A90432-","T90433-","T90434-","A90435-","A90436-","T90437-","T90438-","T90439-","T90440-","T90441-","G90442-","T90443-","G90444-","G90445-","G90446-","A90447-","A90448-","G90449-","T90450-","G90451-","A90452-","T90453-","T90454-","C90455-","A90456-","A90457-","A90458-","A90459-","G90460-","G90461-","A90462-","C90463-","G90464-","T90465-","A90466-","G90467-","A90468-","C90469-","A90470-","A90471-","T90472-","A90473-","C90474-","T90475-","T90476-","T90477-","T90478-","A90479-","C90480-","G90481-","G90482-","A90483-","A90484-","A90485-","A90486-","A90487-","T90488-","G90489-","C90490-","A90491-","T90492-","A90493-","T90494-","A90495-","C90496-","A90497-","G90498-","A90499-","A90500-","T90501-","C90502-","G90503-","C90504-","A90505-","A90506-","T90507-","G90508-","C90509-","T90510-","A90511-","A90512-","A90513-","A90514-","G90515-","A90516-","G90517-","A90518-","T90519-","C90520-","G90521-","T90522-","A90523-","T90524-","T90525-","T90526-","T90527-","T90528-","G90529-","T90530-","T90531-","A90532-","G90533-","A90534-","G90535-","T90536-","A90537-","T90538-","A90539-","T90540-","A90541-","A90542-","C90543-","G90544-","T90545-","T90546-","A90547-","T90548-","G90549-","A90550-","A90551-","A90552-","C90553-","G90554-","A90555-","A90556-","T90557-","T90558-","A90559-","A90560-","T90561-","T90562-","G90563-","T90564-","T90565-","T90566-","T90567-","A90568-","T90569-","A90570-","A90571-","A90572-","C90573-","A90574-","A90575-","A90576-","A90577-","A90578-","T90579-","A90580-","T90581-","A90582-","A90583-","A90584-","G90585-","A90586-","A90587-","A90588-","T90589-","C90590-","G90591-","C151552T","C167451T","T172130-","T172131-","C172132-","C172133-","T173843-","A173844-","G173845-","T173846-","A173847-","A194548-","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","C194595-","G194596-","T194597-","G194598-","T194599-"],"OPG002":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-"],"OPG002_dup":["C44-","L45-","S46-","C47-"],"OPG057":["N267D"],"OPG080":["S84-","N85-"],"OPG178":["S15F"]},"labels":{"aa":"OPG002: K31-, C32-, K33-, D34-, N35-, E36-, Y37-; OPG002_dup: C44-, L45-, S46-, C47-; OPG057: N267D; OPG080: S84-, N85-; OPG178: S15F"}}}]}]},{"name":"NODE_0000103","node_attrs":{"div":563,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C18441T","G22415A","G70002A","C132698T","G143951A","C148604T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G154188A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG031":["E130K"],"OPG089":["R46K"],"OPG165":["D146N"],"OPG174":["M264I"]},"labels":{"aa":"OPG031: E130K; OPG089: R46K; OPG165: D146N; OPG174: M264I"}},"children":[{"name":"OR643708","node_attrs":{"div":565,"accession":"OR643708","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00553/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-07-28"},"strain_display":{"value":"USA/OR643708/2023-07-28"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G70425A","C137966T"],"OPG089":["G187E"],"OPG154":["E29K"]},"labels":{"aa":"OPG089: G187E; OPG154: E29K"}}},{"name":"OR643700","node_attrs":{"div":566,"accession":"OR643700","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00558/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-08-24"},"strain_display":{"value":"USA/OR643700/2023-08-24"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C96773T","A166129G","G168741A"],"OPG117":["S242L"],"OPG195":["R171K"]},"labels":{"aa":"OPG117: S242L; OPG195: R171K"}}},{"name":"OR499974","node_attrs":{"div":563,"accession":"OR499974","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00517/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-06-20"},"strain_display":{"value":"USA/OR499974/2023-06-20"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000104","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.16"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C9389T","C30154T","G161797A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","A185557C"],"OPG188":["E68K"],"OPG210":["K1401T"]},"labels":{"aa":"OPG188: E68K; OPG210: K1401T","clade":"B.1.16"}},"children":[{"name":"OP459211","node_attrs":{"div":561,"accession":"OP459211","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.16"},"strain":{"value":"ANT-LDSP-ANT-MPX-23596-O"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-29"},"strain_display":{"value":"Colombia/OP459211/2022-08-29"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G170076A"]}}},{"name":"OP642383","node_attrs":{"div":561,"accession":"OP642383","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.16"},"strain":{"value":"ANT-LDSP-ANT-MPX-24909-C"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-09"},"strain_display":{"value":"Colombia/OP642383/2022-09-09"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G6863A","C132608T"]}}},{"name":"OP693647","node_attrs":{"div":560,"accession":"OP693647","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.16"},"strain":{"value":"DC_INS_MPX_0082_L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-08"},"strain_display":{"value":"Colombia/OP693647/2022-08-08"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["A1701-","C1702-","T1703-","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-","T196852-","G196853-","T196854-"]}}},{"name":"NODE_0000105","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.16"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G148403A","-180517A","-180518A","-180519T","-180520G","-180521A","-180522C","-180523G","-180524A","-180525T","-180526A","-180527T","-180528A","-180529C","-180530G","-180531G","-180532A","-180533T","-180534T"],"OPG187":["R267K"]},"labels":{"aa":"OPG187: R267K"}},"children":[{"name":"OP837481","node_attrs":{"div":563,"accession":"OP837481","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.16"},"strain":{"value":"VAC_INS_MPX_1050_C"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-26"},"strain_display":{"value":"Colombia/OP837481/2022-10-26"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G69840A","G161421A","C196636-","T196637-","C196638-"]}}},{"name":"OQ148473","node_attrs":{"div":562,"accession":"OQ148473","author":{"author":"Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"country":{"value":"Colombia"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.16"},"strain":{"value":"LBMB-UTP_MP-021_VAC"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-11"},"strain_display":{"value":"Colombia/OQ148473/2022-11-11"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C133212-","C133213-","T133214-","C133215-","G133216-","A133217-","G133218-","T133219-","C133220-","T133221-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","C188896T"]}}}]}]},{"name":"NODE_0000106","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C170573T"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}},"children":[{"name":"OQ451902","node_attrs":{"div":562,"accession":"OQ451902","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/RKI717"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"Germany/OQ451902/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","C3602T","C53342T","C124495T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159789A","G190695A","G193608A"],"OPG003":["E336K"],"OPG003_dup":["E336K"],"OPG016":["E96K"],"OPG071":["R366K"]},"labels":{"aa":"OPG003: E336K; OPG003_dup: E336K; OPG016: E96K; OPG071: R366K"}}},{"name":"OR264459","node_attrs":{"div":559,"accession":"OR264459","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"7_A"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-11"},"strain_display":{"value":"Australia/OR264459/2022-07-11"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["C25644T","G144556A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"NODE_0000107","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N"}},"children":[{"name":"OR759146","node_attrs":{"div":560,"accession":"OR759146","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Canada/ON-PHOL053/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759146/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C3405T","G5375A","C191835T","G193805A"],"OPG015":["A261V"],"OPG015_dup":["A261V"]},"labels":{"aa":"OPG015: A261V; OPG015_dup: A261V"}}},{"name":"NODE_0000108","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C188391T"]}},"children":[{"name":"OP879761","node_attrs":{"div":559,"accession":"OP879761","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"country":{"value":"USA"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"NJ-MPXV-047"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-21"},"strain_display":{"value":"USA/OP879761/2022-07-21"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"OR353575","node_attrs":{"div":562,"accession":"OR353575","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"country":{"value":"USA"},"institution":{"value":"Minnesota Department of Health, Public Health Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MN-MDH-MPXV_0065"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-30"},"strain_display":{"value":"USA/OR353575/2022-08-30"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","C8392T","A20156G","G170867A","T196741-","A196742-","T196743-"],"OPG198":["R277K"]},"labels":{"aa":"OPG198: R277K"}}}]}]}]},{"name":"NODE_0000109","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C118453T","G137276A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177009A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","A196614-"],"OPG136":["E379K"],"OPG153":["S131F"],"OPG205":["E452K"]},"labels":{"aa":"OPG136: E379K; OPG153: S131F; OPG205: E452K"}},"children":[{"name":"NODE_0000110","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C117119T"]}},"children":[{"name":"OQ330972","node_attrs":{"div":561,"accession":"OQ330972","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00372/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-18"},"strain_display":{"value":"USA/OQ330972/2022-10-18"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A763-","A764-","T765-","C128294T","A196675-","T196676-","G196677-"]}}},{"name":"OR499971","node_attrs":{"div":562,"accession":"OR499971","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00514/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-05-04"},"strain_display":{"value":"USA/OR499971/2023-05-04"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T39397C","T178873C","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG057":["N267D"]},"labels":{"aa":"OPG057: N267D"}}}]},{"name":"NODE_0000111","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G635-","A636-","A637-","A1697-","G39327A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T195519-"],"OPG057":["A290V"]},"labels":{"aa":"OPG057: A290V"}},"children":[{"name":"OQ331006","node_attrs":{"div":560,"accession":"OQ331006","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00397/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-03"},"strain_display":{"value":"USA/OQ331006/2023-01-03"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-1697A","-179265C","-179266A","-179267T","-179268G","-179269G","-179270A","-179271T","-179272A","-179273T","-179274C","-179275T","-179276T","-179277T","-179278A","-179279A","-179280A","-179281G","-179282A","-179283A","-179284C","-179285T","-179286A","-179287A","-179288T","-179289C","-179290T","-179291T","-179292A","-179293A","-179294A","-179295A","-179296C","-179297A","-179298T","-179299A","-179300C","-179301G","-179302G","-179303A","-179304T","-179305G","-179306A","-179307A","-179308A","-179309A","-179310T","-179311G","-179312T","-179313T","-179314T","-179315T","-179316G","-179317A","-179318T","-179319T","-179320T","-179321C","-179322T","-179323C","-179324C","-179325A","-179326G","-179327T","-179328T","-179329T","-179330C","-179331C","-179332A","-179333T","-179334T","-179335T","-179336T","-179337A","-179338T","-179339C","-179340T","-179341A","-179342C","-179343T","-179344T","-179345T","-179346A","-179347T","-179348C","-179349T","-179350A","-179351T","-179352T","-179353C","-195519T","T196627-","C196628-","T196629-"]}}},{"name":"OR499967","node_attrs":{"div":560,"accession":"OR499967","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00510/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-05-04"},"strain_display":{"value":"USA/OR499967/2023-05-04"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A672-","C673-","A674-","T196633-","C196634-","T196635-"]}}},{"name":"OR499948","node_attrs":{"div":560,"accession":"OR499948","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00491/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-04-10"},"strain_display":{"value":"USA/OR499948/2023-04-10"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000117","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C43706T","T124690C","C141757T"]},"labels":{"clade":"B.1.18"}},"children":[{"name":"OP628451","node_attrs":{"div":559,"accession":"OP628451","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"strain":{"value":"MpxV/human/USA/WA-UW-083401/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP628451/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP722512","node_attrs":{"div":559,"accession":"OP722512","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00253/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-11"},"strain_display":{"value":"USA/OP722512/2022-10-11"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ121025","node_attrs":{"div":559,"accession":"OQ121025","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,Bell,J.,Hacker,J."},"country":{"value":"USA"},"institution":{"value":"CDPH, VRDL"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"strain":{"value":"hMpxV/USA/CA-CDPH-1000071/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-06"},"strain_display":{"value":"USA/OQ121025/2022-07-06"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ721920","node_attrs":{"div":561,"accession":"OQ721920","author":{"author":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"strain":{"value":"MPXV_USA_2022_IL0009"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721920/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","G78759A","C126911T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","A196614-"],"OPG101":["E92K"],"OPG148":["S309F"]},"labels":{"aa":"OPG101: E92K; OPG148: S309F"}}},{"name":"NODE_0000118","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C170049T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A"]}},"children":[{"name":"OR464199","node_attrs":{"div":565,"accession":"OR464199","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"strain":{"value":"MPXV_USA_2022_NY0051"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OR464199/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C45127T","G91787A","G91880A","G105147A","C114521T"],"OPG064":["E258K"],"OPG133":["M392I"]},"labels":{"aa":"OPG064: E258K; OPG133: M392I"}}},{"name":"NODE_0000119","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G67758A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP819956","node_attrs":{"div":562,"accession":"OP819956","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"strain":{"value":"VAC_INS_MPX_0965_EL"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-12"},"strain_display":{"value":"Colombia/OP819956/2022-10-12"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G28913A"],"OPG045":["S117L"]},"labels":{"aa":"OPG045: S117L"}}},{"name":"OQ148474","node_attrs":{"div":565,"accession":"OQ148474","author":{"author":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"country":{"value":"Colombia"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"strain":{"value":"LBMB-UTP_MP-025_VAC"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-15"},"strain_display":{"value":"Colombia/OQ148474/2022-11-15"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C128242T","G144572A","C166940T","C168829T"],"OPG150":["S155F"],"OPG166":["A59T"]},"labels":{"aa":"OPG150: S155F; OPG166: A59T"}}}]}]}]},{"name":"NODE_0000120","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G181367A","A196614-"]},"labels":{"clade":"B.1.9"}},"children":[{"name":"ON843175","node_attrs":{"div":557,"accession":"ON843175","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0043/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Portugal/ON843175/2022-05-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP693652","node_attrs":{"div":558,"accession":"OP693652","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"strain":{"value":"DC_INS_MPX_0718_L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-16"},"strain_display":{"value":"Colombia/OP693652/2022-08-16"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["-606T","G134122T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP687938","node_attrs":{"div":560,"accession":"OP687938","author":{"author":"Gigante,C.M.,Acheampong,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Morrison,S.S.,Seabolt,M.H.,Weigand,M.R.,Knipe,K.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,McDermott,D.,Li,Y.","value":"Gigante,C.M.,Acheampong,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Morrison,S.S.,Seabolt,M.H.,Weigand,M.R.,Knipe,K.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,McDermott,D.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"strain":{"value":"MPXV_USA_2022_NJ0005"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP687938/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G61329A","C101868T","C103427T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG121":["P27S"]},"labels":{"aa":"OPG121: P27S"}}},{"name":"NODE_0000121","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G176823A"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG205":["E390K"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG205: E390K"}},"children":[{"name":"ON880538","node_attrs":{"div":559,"accession":"ON880538","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"strain":{"value":"MpxV/human/CAN/UN-NML-3336/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-01"},"strain_display":{"value":"Canada/ON880538/2022-06-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-11326A","-11327T","-11328C","-11329T","-11330A","-11331C","-11332G","-11333A","-11334T","-11335A","-11336T","-11337T","-11338A","-11339G","-11340A","-11341T","-11342A","-11343C","-11344T","-11345T","-11346C","-11347A","-11348C","-11349T","-11350C","-11351A","-11352A","-11353T","-11354G","-11355A","-11356A","-11357T","-11358C","-11359A","-11360A","-11361T","-11362C","-11363A","-11364C","-11365A","-11366C","-11367A","-11368A","-11369T","-11370C","-11371T","-11372A","-11373A","-11374T","-11375G","-11376T","-11377A","-11378G","-11379G","-11380T","-11381T","-11382T","-11383A","-11384T","-11385G","-11386A","-11387C","-11388A","-11389T","-11390A","-11391A","-11392T","-11393A","-11394G","-11395C","-11396A","-11397T","-11398T","-11399T","-11400T","-11401C","-11402A","-11403G","-11404C","-11405A","-11406G","-11407T","-11408T","-11409C","-11410A","-11411A","-11412T","-11413G","-11414T","-11415T","-11416T","-11417C","-11418T","-11419A","-11420G","-11421A","-11422T","-11423T","-11424C","-11425G","-11426T","-11427T","-11428G","-11429A","-11430T","-11431G","-11432G","-11433C","-11434A","-11435A","-11436T","-11437G","-11438G","-11439T","-11440T","-11441A","-11442T","-11443A","-11444C","-11445A","-11446T","-11447G","-11448T","-11449A","-11450T","-11451A","-11452T","-11453C","-11454C","-11455G","-11456T","-11457T","-11458A","-11459T","-11460T","-11461T","-11462G","-11463A","-11464T","-11465C","-11466T","-11467A","-11468A","-11469T","-11470G","-11471T","-11472T","-11473G","-11474A","-11475C","-11476A","-11477T","-11478C","-11479T","-11480G","-11481A","-11482A","-11483C","-11484C","-11485G","-11486G","-11487A","-11488T","-11489T","-11490C","-11491T","-11492A","-11493G","-11494C","-11495A","-11496G","-11497T","-11498A","-11499A","-11500A","-11501G","-11502A","-11503T","-11504A","-11505C","-11506T","-11507A","-11508G","-11509A","-11510G","-11511A","-11512T","-11513T","-11514G","-11515T","-11516T","-11517T","-11518A","-11519T","-11520T","-11521A","-11522T","-11523A","-11524T","-11525C","-11526T","-11527A","-11528A","-11529C","-11530A","-11531G","-11532C","-11533C","-11534T","-11535T","-11536G","-11537T","-11538G","-11539A","-11540A","-11541G","-11542A","-11543A","-11544G","-11545T","-11546G","-11547T","-11548T","-11549T","-11550C","-11551T","-11552C","-11553C","-11554T","-11555C","-11556G","-11557T","-11558T","-11559T","-11560G","-11561T","-11562C","-11563A","-11564A","-11565T","-11566C","-11567A","-11568T","-11569G","-11570T","-11571T","-11572A","-11573A","-11574T","-11575G","-11576T","-11577C","-11578T","-11579T","-11580T","-11581A","-11582A","-11583G","-11584A","-11585T","-11586A","-11587A","-11588G","-11589G","-11590T","-11591A","-11592G","-11593A","-11594C","-11595A","-11596A","-11597A","-11598T","-11599G","-11600T","-11601T","-11602T","-11603A","-11604T","-11605A","-11606G","-11607T","-11608A","-11609C","-11610T","-11611A","-11612A","-11613G","-11614A","-11615A","-11616T","-11617T","-11618G","-11619G","-11620G","-11621C","-11622A","-11623A","-11624A","-11625C","-11626A","-11627T","-11628A","-11629A","-11630G","-11631A","-11632C","-11633A","-11634T","-11635G","-11636T","-11637C","-11638A","-11639C","-11640A","-11641A","-11642A","-11643G","-11644A","-11645C","-11646C","-11647C","-11648T","-11649T","-11650T","-11651T","-11652T","-11653G","-11654T","-11655A","-11656T","-11657G","-11658T","-11659A","-11660T","-11661A","-11662A","-11663G","-11664T","-11665G","-11666T","-11667A","-11668G","-11669A","-11670A","-11671A","-11672T","-11673T","-11674A","-11675T","-11676A","-11677A","-11678C","-11679A","-11680T","-11681C","-11682C","-11683A","-11684T","-11685A","-11686G","-11687T","-11688T","-11689G","-11690G","-11691A","-11692T","-11693T","-11694C","-11695A","-11696C","-11697A","-11698T","-11699A","-11700G","-11701G","-11702T","-11703G","-11704T","-11705C","-11706C","-11707A","-11708A","-11709T","-11710C","-11711G","-11712G","-11713G","-11714A","-11715T","-11716C","-11717T","-11718C","-11719T","-11720C","-11721C","-11722A","-11723T","-11724C","-11725A","-11726T","-11727C","-11728G","-11729A","-11730G","-11731A","-11732T","-11733G","-11734A","-11735T","-11736T","-11737G","-11738A","-11739C","-11740G","-11741G","-11742C","-11743A","-11744T","-11745C","-11746T","-11747C","-11748C","-11749C","-11750C","-11751C","-11752T","-11753T","-11754C","-11755C","-11756T","-11757T","-11758T","-11759T","-11760T","-11761T","-11762A","-11763G","-11764T","-11765A","-11766G","-11767A","-11768T","-11769A","-11770T","-11771T","-11772T","-11773C","-11774A","-11775T","-11776C","-11777G","-11778T","-11779G","-11780T","-11781A","-11782A","-11783G","-11784A","-11785A","-11786T","-11787C","-11788A","-11789A","-11790T","-11791A","-11792T","-11793T","-11794A","-11795A","-11796T","-11797A","-11798T","-11799T","-11800T","-11801C","-11802T","-11803A","-11804A","-11805A","-11806G","-11807T","-11808A","-11809T","-11810C","-11811T","-11812G","-11813T","-11814G","-11815T","-11816A","-11817T","-11818A","-11819G","-11820C","-11821C","-11822T","-11823C","-11824T","-11825T","-11826T","-11827A","-11828T","-11829T","-11830T","-11831A","-11832C","-11833C","-11834A","-11835C","-11836A","-11837G","-11838C","-11839T","-11840C","-11841C","-11842A","-11843T","-11844A","-11845T","-11846T","-11847C","-11848C","-11849A","-11850A","-11851C","-11852A","-11853T","-11854G","-11855C","-11856A","-11857T","-11858T","-11859C","-11860C","-11861A","-11862C","-11863T","-11864A","-11865G","-11866A","-11867G","-11868G","-11869G","-11870A","-11871T","-11872A","-11873T","-11874C","-11875G","-11876A","-11877T","-11878A","-11879T","-11880C","-11881G","-11882C","-11883C","-11884G","-11885A","-11886A","-11887T","-11888G","-11889T","-11890C","-11891A","-11892T","-11893A","-11894T","-11895A","-11896C","-11897T","-11898C","-11899A","-11900A","-11901T","-11902T","-11903A","-11904G","-11905T","-11906A","-11907T","-11908A","-11909T","-11910G","-11911T","-11912T","-11913G","-11914G","-11915A","-11916G","-11917G","-11918A","-11919C","-11920A","-11921T","-11922C","-11923C","-11924G","-11925A","-11926G","-11927T","-11928T","-11929C","-11930A","-11931T","-11932T","-11933G","-11934T","-11935T","-11936T","-11937T","-11938C","-11939A","-11940A","-11941T","-11942A","-11943T","-11944C","-11945A","-11946A","-11947A","-11948G","-11949A","-11950G","-11951A","-11952T","-11953G","-11954G","-11955T","-11956T","-11957T","-11958C","-11959C","-11960T","-11961T","-11962A","-11963T","-11964C","-11965A","-11966T","-11967T","-11968T","-11969C","-11970T","-11971C","-11972C","-11973A","-11974T","-11975A","-11976G","-11977T","-11978G","-11979G","-11980T","-11981A","-11982C","-11983A","-11984A","-11985T","-11986A","-11987C","-11988T","-11989A","-11990C","-11991A","-11992C","-11993A","-11994T","-11995T","-11996A","-11997T","-11998T","-11999C","-12000C","-12001G","-12002T","-12003A","-12004C","-12005G","-12006G","-12007C","-12008T","-12009T","-12010T","-12011C","-12012C","-12013A","-12014T","-12015T","-12016C","-12017T","-12018C","-12019C","-12020A","-12021A","-12022A","-12023A","-12024A","-12025C","-12026A","-12027A","-12028T","-12029T","-12030T","-12031T","-12032A","-12033C","-12034C","-12035A","-12036A","-12037A","-12038T","-12039C","-12040T","-12041A","-12042A","-12043A","-12044T","-12045C","-12046T","-12047A","-12048C","-12049A","-12050T","-12051C","-12052T","-12053T","-12054T","-12055A","-12056T","-12057T","-12058G","-12059T","-12060A","-12061T","-12062C","-12063T","-12064A","-12065T","-12066A","-12067A","-12068T","-12069C","-12070A","-12071C","-12072T","-12073A","-12074T","-12075T","-12076T","-12077A","-12078G","-12079A","-12080T","-12081A","-12082A","-12083T","-12084C","-12085A","-12086G","-12087C","-12088C","-12089A","-12090T","-12091A","-12092A","-12093T","-12094T","-12095C","-12096C","-12097T","-12098C","-12099G","-12100A","-12101G","-12102T","-12103G","-12104C","-12105A","-12106A","-12107C","-12108A","-12109T","-12110G","-12111T","-12112T","-12113A","-12114G","-12115A","-12116T","-12117C","-12118G","-12119T","-12120C","-12121T","-12122A","-12123T","-12124A","-12125T","-12126A","-12127T","-12128G","-12129A","-12130A","-12131T","-12132A","-12133A","-12134G","-12135C","-12136C","-12137G","-12138T","-12139G","-12140T","-12141T","-12142A","-12143T","-12144C","-12145T","-12146A","-12147T","-12148T","-12149C","-12150C","-12151T","-12152T","-12153T","-12154C","-12155A","-12156T","-12157T","-12158A","-12159A","-12160C","-12161A","-12162A","-12163T","-12164T","-12165T","-12166A","-12167A","-12168C","-12169G","-12170A","-12171T","-12172G","-12173T","-12174C","-12175T","-12176A","-12177T","-12178A","-12179T","-12180C","-12181T","-12182A","-12183T","-12184A","-12185T","-12186G","-12187A","-12188G","-12189A","-12190T","-12191G","-12192A","-12193C","-12194T","-12195T","-12196A","-12197A","-12198T","-12199A","-12200T","-12201A","-12202A","-12203T","-12204A","-12205T","-12206T","-12207G","-12208A","-12209A","-12210G","-12211A","-12212G","-12213C","-12214T","-12215G","-12216T","-12217A","-12218C","-12219A","-12220A","-12221T","-12222A","-12223G","-12224T","-12225T","-12226T","-12227T","-12228T","-12229A","-12230T","-12231C","-12232T","-12233A","-12234T","-12235A","-12236G","-12237A","-12238A","C32627T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"],"OPG023":["-222S","-223I","-224D","-225K","-226N","-227Y","-228C","-229T","-230A","-231L","-232Q","-233Y","-234Y","-235I","-236K","-237S","-238S","-239H","-240I","-241D","-242I","-243D","-244I","-245V","-246K","-247L","-248L","-249M","-250K","-251G","-252I","-253D","-254N","-255T","-256A","-257Y","-258S","-259Y","-260I","-261D","-262D","-263L","-264T","-265C","-266C","-267T","-268R","-269G","-270I","-271M","-272A","-273D","-274Y","-275L","-276N","-277S","-278D","-279Y","-280R","-281Y","-282N","-283K","-284D","-285V","-286D","-287L","-288D","-289L","-290V","-291K","-292L","-293F","-294L","-295E","-296N","-297G","-298K","-299P","-300Y","-301G","-302I","-303M","-304C","-305S","-306I","-307V","-308P","-309L","-310W","-311R","-312N","-313D","-314K","-315E","-316T","-317I","-318S","-319L","-320I","-321L","-322K","-323T","-324M","-325N","-326S","-327D","-328V","-329L","-330Q","-331H","-332I","-333L","-334I","-335E","-336Y","-337M","-338T","-339F","-340G","-341D","-342I","-343D","-344I","-345P","-346L","-347V","-348E","-349C","-350M","-351L","-352E","-353Y","-354G","-355A","-356V","-357V","-358N","-359K","-360E","-361A","-362I","-363H","-364R","-365Y","-366F","-367R","-368N","-369I","-370N","-371I","-372D","-373S","-374Y","-375T","-376M","-377K","-378Y","-379L","-380L","-381K","-382K","-383E","-384G","-385G","-386D","-387A","-388V","-389N","-390H","-391L","-392D","-393D","-394G","-395E","-396I","-397P","-398I","-399G","-400H","-401L","-402C","-403E","-404S","-405N","-406Y","-407G","-408C","-409Y","-410N","-411F","-412Y","-413T","-414Y","-415T","-416Y","-417K","-418K","-419G","-420L","-421C","-422D","-423M","-424S","-425Y","-426V","-427C","-428P","-429I","-430L","-431S","-432T","-433I","-434N","-435I","-436C","-437L","-438P","-439Y","-440L","-441K","-442D","-443I","-444N","-445M","-446I","-447D","-448K","-449R","-450G","-451E","-452T","-453L","-454L","-455H","-456K","-457A","-458V","-459R","-460Y","-461N","-462K","-463Q","-464S","-465L","-466V","-467S","-468L","-469L","-470L","-471E","-472S","-473G","-474S","-475D","-476V","-477N","-478I","-479R","-480S","-481N","-482N","-483G","-484Y","-485T","-486C","-487I","-488T","-489I","-490A","-491I","-492N","-493E","-494S","-495R","-496N","-497I","-498E","-499L","-500L","-501K","-502M","-503L","-504L","-505C","-506H","-507K","-508P","-509T","-510L","-511D","-512C","-513V","-514I","-515D","-516S","-517L","-518S","-519E","-520V","-521S","-522N","-523I","-524V","-525D"]},"labels":{"aa":"OPG023: -222S, -223I, -224D, -225K, -226N, -227Y, -228C, -229T, -230A, -231L, -232Q, -233Y, -234Y, -235I, -236K, -237S, -238S, -239H, -240I, -241D, -242I, -243D, -244I, -245V, -246K, -247L, -248L, -249M, -250K, -251G, -252I, -253D, -254N, -255T, -256A, -257Y, -258S, -259Y, -260I, -261D, -262D, -263L, -264T, -265C, -266C, -267T, -268R, -269G, -270I, -271M, -272A, -273D, -274Y, -275L, -276N, -277S, -278D, -279Y, -280R, -281Y, -282N, -283K, -284D, -285V, -286D, -287L, -288D, -289L, -290V, -291K, -292L, -293F, -294L, -295E, -296N, -297G, -298K, -299P, -300Y, -301G, -302I, -303M, -304C, -305S, -306I, -307V, -308P, -309L, -310W, -311R, -312N, -313D, -314K, -315E, -316T, -317I, -318S, -319L, -320I, -321L, -322K, -323T, -324M, -325N, -326S, -327D, -328V, -329L, -330Q, -331H, -332I, -333L, -334I, -335E, -336Y, -337M, -338T, -339F, -340G, -341D, -342I, -343D, -344I, -345P, -346L, -347V, -348E, -349C, -350M, -351L, -352E, -353Y, -354G, -355A, -356V, -357V, -358N, -359K, -360E, -361A, -362I, -363H, -364R, -365Y, -366F, -367R, -368N, -369I, -370N, -371I, -372D, -373S, -374Y, -375T, -376M, -377K, -378Y, -379L, -380L, -381K, -382K, -383E, -384G, -385G, -386D, -387A, -388V, -389N, -390H, -391L, -392D, -393D, -394G, -395E, -396I, -397P, -398I, -399G, -400H, -401L, -402C, -403E, -404S, -405N, -406Y, -407G, -408C, -409Y, -410N, -411F, -412Y, -413T, -414Y, -415T, -416Y, -417K, -418K, -419G, -420L, -421C, -422D, -423M, -424S, -425Y, -426V, -427C, -428P, -429I, -430L, -431S, -432T, -433I, -434N, -435I, -436C, -437L, -438P, -439Y, -440L, -441K, -442D, -443I, -444N, -445M, -446I, -447D, -448K, -449R, -450G, -451E, -452T, -453L, -454L, -455H, -456K, -457A, -458V, -459R, -460Y, -461N, -462K, -463Q, -464S, -465L, -466V, -467S, -468L, -469L, -470L, -471E, -472S, -473G, -474S, -475D, -476V, -477N, -478I, -479R, -480S, -481N, -482N, -483G, -484Y, -485T, -486C, -487I, -488T, -489I, -490A, -491I, -492N, -493E, -494S, -495R, -496N, -497I, -498E, -499L, -500L, -501K, -502M, -503L, -504L, -505C, -506H, -507K, -508P, -509T, -510L, -511D, -512C, -513V, -514I, -515D, -516S, -517L, -518S, -519E, -520V, -521S, -522N, -523I, -524V, -525D"}}},{"name":"ON585038","node_attrs":{"div":559,"accession":"ON585038","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0008/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-15"},"strain_display":{"value":"Portugal/ON585038/2022-05-15"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C16968T","A188351-"]}}},{"name":"OP555485","node_attrs":{"div":560,"accession":"OP555485","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0389/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-12"},"strain_display":{"value":"Portugal/OP555485/2022-07-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-606T","C57110T","G159148A","-196614A"],"OPG074":["E6K"],"OPG185":["D78N"]},"labels":{"aa":"OPG074: E6K; OPG185: D78N"}}},{"name":"NODE_0000122","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C34432T"],"OPG053":["E87K"]},"labels":{"aa":"OPG053: E87K"}},"children":[{"name":"OP414351","node_attrs":{"div":561,"accession":"OP414351","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0319/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-04"},"strain_display":{"value":"Portugal/OP414351/2022-06-04"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G25534A","G96524A"],"OPG117":["R159K"]},"labels":{"aa":"OPG117: R159K"}}},{"name":"OP555631","node_attrs":{"div":562,"accession":"OP555631","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0560/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-30"},"strain_display":{"value":"Portugal/OP555631/2022-08-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T594A","-606T","-607T","-608T","-609T","-11326A","-11327T","-11328C","-11329T","-11330A","-11331C","-11332G","-11333A","-11334T","-11335A","-11336T","-11337T","-11338A","-11339G","-11340A","-11341T","-11342A","-11343C","-11344T","-11345T","-11346C","-11347A","-11348C","-11349T","-11350C","-11351A","-11352A","-11353T","-11354G","-11355A","-11356A","-11357T","-11358C","-11359A","-11360A","-11361T","-11362C","-11363A","-11364C","-11365A","-11366C","-11367A","-11368A","-11369T","-11370C","-11371T","-11372A","-11373A","-11374T","-11375G","-11376T","-11377A","-11378G","-11379G","-11380T","-11381T","-11382T","-11383A","-11384T","-11385G","-11386A","-11387C","-11388A","-11389T","-11390A","-11391A","-11392T","-11393A","-11394G","-11395C","-11396A","-11397T","-11398T","-11399T","-11400T","-11401C","-11402A","-11403G","-11404C","-11405A","-11406G","-11407T","-11408T","-11409C","-11410A","-11411A","-11412T","-11413G","-11414T","-11415T","-11416T","-11417C","-11418T","-11419A","-11420G","-11421A","-11422T","-11423T","-11424C","-11425G","-11426T","-11427T","-11428G","-11429A","-11430T","-11431G","-11432G","-11433C","-11434A","-11435A","-11436T","-11437G","-11438G","-11439T","-11440T","-11441A","-11442T","-11443A","-11444C","-11445A","-11446T","-11447G","-11448T","-11449A","-11450T","-11451A","-11452T","-11453C","-11454C","-11455G","-11456T","-11457T","-11458A","-11459T","-11460T","-11461T","-11462G","-11463A","-11464T","-11465C","-11466T","-11467A","-11468A","-11469T","-11470G","-11471T","-11472T","-11473G","-11474A","-11475C","-11476A","-11477T","-11478C","-11479T","-11480G","-11481A","-11482A","-11483C","-11484C","-11485G","-11486G","-11487A","-11488T","-11489T","-11490C","-11491T","-11492A","-11493G","-11494C","-11495A","-11496G","-11497T","-11498A","-11499A","-11500A","-11501G","-11502A","-11503T","-11504A","-11505C","-11506T","-11507A","-11508G","-11509A","-11510G","-11511A","-11512T","-11513T","-11514G","-11515T","-11516T","-11517T","-11518A","-11519T","-11520T","-11521A","-11522T","-11523A","-11524T","-11525C","-11526T","-11527A","-11528A","-11529C","-11530A","-11531G","-11532C","-11533C","-11534T","-11535T","-11536G","-11537T","-11538G","-11539A","-11540A","-11541G","-11542A","-11543A","-11544G","-11545T","-11546G","-11547T","-11548T","-11549T","-11550C","-11551T","-11552C","-11553C","-11554T","-11555C","-11556G","-11557T","-11558T","-11559T","-11560G","-11561T","-11562C","-11563A","-11564A","-11565T","-11566C","-11567A","-11568T","-11569G","-11570T","-11571T","-11572A","-11573A","-11574T","-11575G","-11576T","-11577C","-11578T","-11579T","-11580T","-11581A","-11582A","-11583G","-11584A","-11585T","-11586A","-11587A","-11588G","-11589G","-11590T","-11591A","-11592G","-11593A","-11594C","-11595A","-11596A","-11597A","-11598T","-11599G","-11600T","-11601T","-11602T","-11603A","-11604T","-11605A","-11606G","-11607T","-11608A","-11609C","-11610T","-11611A","-11612A","-11613G","-11614A","-11615A","-11616T","-11617T","-11618G","-11619G","-11620G","-11621C","-11622A","-11623A","-11624A","-11625C","-11626A","-11627T","-11628A","-11629A","-11630G","-11631A","-11632C","-11633A","-11634T","-11635G","-11636T","-11637C","-11638A","-11639C","-11640A","-11641A","-11642A","-11643G","-11644A","-11645C","-11646C","-11647C","-11648T","-11649T","-11650T","-11651T","-11652T","-11653G","-11654T","-11655A","-11656T","-11657G","-11658T","-11659A","-11660T","-11661A","-11662A","-11663G","-11664T","-11665G","-11666T","-11667A","-11668G","-11669A","-11670A","-11671A","-11672T","-11673T","-11674A","-11675T","-11676A","-11677A","-11678C","-11679A","-11680T","-11681C","-11682C","-11683A","-11684T","-11685A","-11686G","-11687T","-11688T","-11689G","-11690G","-11691A","-11692T","-11693T","-11694C","-11695A","-11696C","-11697A","-11698T","-11699A","-11700G","-11701G","-11702T","-11703G","-11704T","-11705C","-11706C","-11707A","-11708A","-11709T","-11710C","-11711G","-11712G","-11713G","-11714A","-11715T","-11716C","-11717T","-11718C","-11719T","-11720C","-11721C","-11722A","-11723T","-11724C","-11725A","-11726T","-11727C","-11728G","-11729A","-11730G","-11731A","-11732T","-11733G","-11734A","-11735T","-11736T","-11737G","-11738A","-11739C","-11740G","-11741G","-11742C","-11743A","-11744T","-11745C","-11746T","-11748C","-11749C","-11750C","-11751C","-11752T","-11753T","-11754C","-11755C","-11756T","-11757T","-11758T","-11759T","-11760T","-11761T","-11762A","-11763G","-11764T","-11765A","-11766G","-11767A","-11769A","-11770T","-11773C","-11828T","-11829T","-11830T","-11831A","-11836A","-11837G","-11838C","-11842A","-11843T","-11844A","-11845T","-11846T","-11847C","-11848C","-11849A","-11850A","-11851C","-11852A","-11853T","-11854G","-11855C","-11856A","-11857T","-11858T","-11859C","-11860C","-11861A","-11862C","-11863T","-11864A","-11865G","-11866A","-11867G","-11868G","-11869G","-11870A","-11871T","-11872A","-11873T","-11874C","-11875G","-11876A","-11877T","-11878A","-11879T","-11880C","-11881G","-11882C","-11883C","-11884G","-11885A","-11886A","-11887T","-11888G","-11889T","-11890C","-11891A","-11892T","-11893A","-11894T","-11895A","-11896C","-11897T","-11898C","-11899A","-11900A","-11901T","-11902T","-11903A","-11904G","-11905T","-11906A","-11907T","-11908A","-11909T","-11910G","-11911T","-11912T","-11913G","-11914G","-11915A","-11916G","-11917G","-11918A","-11919C","-11920A","-11921T","-11922C","-11923C","-11924G","-11925A","-11926G","-11927T","-11928T","-11929C","-11930A","-11931T","-11932T","-11933G","-11934T","-11935T","-11936T","-11937T","-11938C","-11939A","-11940A","-11941T","-11942A","-11943T","-11944C","-11945A","-11946A","-11947A","-11948G","-11949A","-11950G","-11951A","-11952T","-11953G","-11954G","-11955T","-11956T","-11957T","-11958C","-11959C","-11960T","-11961T","-11962A","-11963T","-11964C","-11965A","-11966T","-11967T","-11968T","-11969C","-11970T","-11971C","-11972C","-11973A","-11974T","-11975A","-11976G","-11977T","-11978G","-11979G","-11980T","-11981A","-11982C","-11983A","-11984A","-11985T","-11986A","-11987C","-11988T","-11989A","-11990C","-11991A","-11992C","-11993A","-11994T","-11995T","-11996A","-11997T","-11998T","-11999C","-12000C","-12001G","-12002T","-12003A","-12004C","-12005G","-12006G","-12007C","-12008T","-12009T","-12010T","-12011C","-12012C","-12013A","-12014T","-12015T","-12016C","-12017T","-12018C","-12019C","-12020A","-12021A","-12022A","-12023A","-12024A","-12025C","-12026A","-12027A","-12028T","-12029T","-12030T","-12031T","-12032A","-12033C","-12034C","-12035A","-12036A","-12037A","-12038T","-12039C","-12040T","-12041A","-12042A","-12043A","-12044T","-12045C","-12046T","-12047A","-12048C","-12049A","-12050T","-12051C","-12053T","-12054T","-12055A","-12056T","-12057T","-12058G","-12059T","-12060A","-12062C","-12063T","-12064A","-12065T","-12066A","-12067A","-12068T","-12069C","-12070A","-12071C","-12073A","-12074T","-12075T","-12076T","-12077A","-12078G","-12079A","-12080T","-12081A","-12082A","-12083T","-12084C","-12085A","-12187A","-12189A","-12190T","-12191G","-12192A","-12193C","-12194T","-12195T","-12196A","-12197A","-12198T","-12199A","-12200T","-12201A","-12202A","-12203T","-12204A","-12205T","-12206T","-12207G","-12208A","-12209A","-12210G","-12211A","-12212G","-12213C","-12214T","-12215G","-12216T","-12217A","-12218C","-12219A","-12220A","-12221T","-12222A","-12223G","-12224T","-12225T","-12226T","-12227T","-12228T","-12229A","-12230T","-12231C","-12232T","-12233A","-12234T","-12235A","-12236G","-12237A","C68792T","G119156A","G155157A","-196614A","-196615A","-196616T","-196617A"],"OPG023":["-222S","-223I","-224D","-225K","-226N","-227Y","-228C","-229T","-230A","-231L","-232Q","-233Y","-234Y","-235I","-236K","-237S","-273D","-274Y","-275L","-276N","-278D","-279Y","-281Y","-282N","-284D","-285V","-286D","-287L","-288D","-289L","-290V","-291K","-292L","-293F","-294L","-295E","-296N","-297G","-298K","-299P","-300Y","-301G","-302I","-303M","-304C","-305S","-306I","-307V","-308P","-309L","-310W","-311R","-312N","-313D","-314K","-315E","-316T","-317I","-318S","-319L","-320I","-321L","-322K","-323T","-324M","-325N","-326S","-327D","-328V","-329L","-330Q","-331H","-332I","-333L","-334I","-335E","-336Y","-337M","-338T","-339F","-340G","-341D","-342I","-343D","-344I","-345P","-346L","-347V","-348E","-349C","-350M","-351L","-352E","-353Y","-355A","-379L","-380L","-381K","-382K","-383E","-384G","-386D","-387A","-388V","-389N","-390H","-391L","-392D","-393D","-394G","-395E","-396I","-397P","-398I","-399G","-400H","-401L","-402C","-403E","-404S","-405N","-406Y","-407G","-408C","-409Y","-410N","-411F","-412Y","-413T","-414Y","-415T","-416Y","-417K","-418K","-419G","-420L","-421C","-422D","-423M","-424S","-425Y","-426V","-427C","-428P","-429I","-430L","-431S","-432T","-433I","-434N","-435I","-436C","-437L","-438P","-439Y","-440L","-441K","-442D","-443I","-444N","-445M","-446I","-447D","-448K","-449R","-450G","-451E","-452T","-453L","-454L","-455H","-456K","-457A","-458V","-459R","-460Y","-461N","-462K","-463Q","-464S","-465L","-466V","-467S","-468L","-469L","-470L","-471E","-472S","-473G","-474S","-475D","-476V","-477N","-478I","-479R","-480S","-481N","-482N","-483G","-484Y","-485T","-486C","-487I","-488T","-489I","-490A","-491I","-492N","-493E","-494S","-495R","-496N","-497I","-498E","-499L","-500L","-501K","-502M","-503L","-504L","-505C","-506H","-507K","-508P","-509T","-510L","-511D","-512C","-513V","-514I","-515D","-516S","-517L","-518S","-519E","-520V","-521S","-522N","-523I","-524V","-525D"],"OPG181":["R249K"]},"labels":{"aa":"OPG023: -222S, -223I, -224D, -225K, -226N, -227Y, -228C, -229T, -230A, -231L, -232Q, -233Y, -234Y, -235I, -236K, -237S, -273D, -274Y, -275L, -276N, -278D, -279Y, -281Y, -282N, -284D, -285V, -286D, -287L, -288D, -289L, -290V, -291K, -292L, -293F, -294L, -295E, -296N, -297G, -298K, -299P, -300Y, -301G, -302I, -303M, -304C, -305S, -306I, -307V, -308P, -309L, -310W, -311R, -312N, -313D, -314K, -315E, -316T, -317I, -318S, -319L, -320I, -321L, -322K, -323T, -324M, -325N, -326S, -327D, -328V, -329L, -330Q, -331H, -332I, -333L, -334I, -335E, -336Y, -337M, -338T, -339F, -340G, -341D, -342I, -343D, -344I, -345P, -346L, -347V, -348E, -349C, -350M, -351L, -352E, -353Y, -355A, -379L, -380L, -381K, -382K, -383E, -384G, -386D, -387A, -388V, -389N, -390H, -391L, -392D, -393D, -394G, -395E, -396I, -397P, -398I, -399G, -400H, -401L, -402C, -403E, -404S, -405N, -406Y, -407G, -408C, -409Y, -410N, -411F, -412Y, -413T, -414Y, -415T, -416Y, -417K, -418K, -419G, -420L, -421C, -422D, -423M, -424S, -425Y, -426V, -427C, -428P, -429I, -430L, -431S, -432T, -433I, -434N, -435I, -436C, -437L, -438P, -439Y, -440L, -441K, -442D, -443I, -444N, -445M, -446I, -447D, -448K, -449R, -450G, -451E, -452T, -453L, -454L, -455H, -456K, -457A, -458V, -459R, -460Y, -461N, -462K, -463Q, -464S, -465L, -466V, -467S, -468L, -469L, -470L, -471E, -472S, -473G, -474S, -475D, -476V, -477N, -478I, -479R, -480S, -481N, -482N, -483G, -484Y, -485T, -486C, -487I, -488T, -489I, -490A, -491I, -492N, -493E, -494S, -495R, -496N, -497I, -498E, -499L, -500L, -501K, -502M, -503L, -504L, -505C, -506H, -507K, -508P, -509T, -510L, -511D, -512C, -513V, -514I, -515D, -516S, -517L, -518S, -519E, -520V, -521S, -522N, -523I, -524V, -525D; OPG181: R249K"}}}]}]}]},{"name":"NODE_0000123","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G12169A","G44960A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]},"labels":{"clade":"B.1.17"}},"children":[{"name":"OP442552","node_attrs":{"div":558,"accession":"OP442552","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00085/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-13"},"strain_display":{"value":"USA/OP442552/2022-07-13"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G771-","T772-","G773-","A196789-","A196790-","T196791-"]}}},{"name":"OP392546","node_attrs":{"div":562,"accession":"OP392546","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"strain":{"value":"MpxV/human/USA/WA-UW-085171/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP392546/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A11836G","G69249A","C113363T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G171959A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG132":["D60N"]},"labels":{"aa":"OPG132: D60N"}}},{"name":"OP748959","node_attrs":{"div":559,"accession":"OP748959","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00273/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-14"},"strain_display":{"value":"USA/OP748959/2022-07-14"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T658-","A659-","T660-","A11160G"],"OPG023":["F581L"]},"labels":{"aa":"OPG023: F581L"}}},{"name":"OQ054244","node_attrs":{"div":558,"accession":"OQ054244","author":{"author":"Gigante,C.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y.","value":"Gigante,C.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"strain":{"value":"MPXV_USA_2022_CA0029"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ054244/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A173316-","T173317-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP890564","node_attrs":{"div":559,"accession":"OP890564","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00336/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-09"},"strain_display":{"value":"USA/OP890564/2022-11-09"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A39482T"],"OPG057":["H238Q"]},"labels":{"aa":"OPG057: H238Q"}}},{"name":"OP890547","node_attrs":{"div":558,"accession":"OP890547","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00289/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-04"},"strain_display":{"value":"USA/OP890547/2022-10-04"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000124","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A39395-","T39396-","T39397-","C85931T","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG057":["N267-"]},"labels":{"aa":"OPG057: N267-"}},"children":[{"name":"OQ547899","node_attrs":{"div":562,"accession":"OQ547899","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"country":{"value":"USA"},"institution":{"value":"CDPH, VRDL"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000184/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-10"},"strain_display":{"value":"USA/OQ547899/2023-01-10"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G71249A","G172895A","-179079A","-179080T","-179081A","G182189A"],"OPG090":["R24Q"]},"labels":{"aa":"OPG090: R24Q"}}},{"name":"OQ503816","node_attrs":{"div":559,"accession":"OQ503816","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00423/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-02"},"strain_display":{"value":"USA/OQ503816/2022-12-02"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179176A","-179177T","-179178A"]}}}]}]},{"name":"NODE_0000125","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","G149818A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G151362A"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG176":["D4N"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG176: D4N","clade":"B.1.15"}},"children":[{"name":"ON694335","node_attrs":{"div":558,"accession":"ON694335","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/Germany/2022/RKI018"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/ON694335/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-","A196614-"]}}},{"name":"OP324453","node_attrs":{"div":559,"accession":"OP324453","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"strain":{"value":"Monkeypox/PT0129/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-12"},"strain_display":{"value":"Portugal/OP324453/2022-07-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","C18133T","-196615A","-196616T"]}}},{"name":"OP484673","node_attrs":{"div":561,"accession":"OP484673","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/Germany/2022/RKI352"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP484673/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C21128T","G74187T","C151111T"],"OPG037":["E436K"],"OPG094":["Q136H"]},"labels":{"aa":"OPG037: E436K; OPG094: Q136H"}}},{"name":"OP764619","node_attrs":{"div":558,"accession":"OP764619","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/Germany/2022/RKI561"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OP764619/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000126","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C8385T","-11326A","-11327T","-11328C","-11329T","-11330A","-11331C","-11332G","-11333A","-11334T","-11335A","-11336T","-11337T","-11338A","-11339G","-11340A","-11341T","-11342A","-11343C","-11344T","-11345T","-11346C","-11347A","-11348C","-11349T","-11350C","-11351A","-11352A","-11353T","-11354G","-11355A","-11356A","-11357T","-11358C","-11359A","-11360A","-11361T","-11362C","-11363A","-11364C","-11365A","-11366C","-11367A","-11368A","-11369T","-11370C","-11371T","-11372A","-11373A","-11374T","-11375G","-11376T","-11377A","-11378G","-11379G","-11380T","-11381T","-11382T","-11383A","-11384T","-11385G","-11386A","-11387C","-11388A","-11389T","-11390A","-11391A","-11392T","-11393A","-11394G","-11395C","-11396A","-11397T","-11398T","-11399T","-11400T","-11401C","-11402A","-11403G","-11404C","-11405A","-11406G","-11407T","-11408T","-11409C","-11410A","-11411A","-11412T","-11413G","-11414T","-11415T","-11416T","-11417C","-11418T","-11419A","-11420G","-11421A","-11422T","-11423T","-11424C","-11425G","-11426T","-11427T","-11428G","-11429A","-11430T","-11431G","-11432G","-11433C","-11434A","-11435A","-11436T","-11437G","-11438G","-11439T","-11440T","-11441A","-11442T","-11443A","-11444C","-11445A","-11446T","-11447G","-11448T","-11449A","-11450T","-11451A","-11452T","-11453C","-11454C","-11455G","-11456T","-11457T","-11458A","-11459T","-11460T","-11461T","-11462G","-11463A","-11464T","-11465C","-11466T","-11467A","-11468A","-11469T","-11470G","-11471T","-11472T","-11473G","-11474A","-11475C","-11476A","-11477T","-11478C","-11479T","-11480G","-11481A","-11482A","-11483C","-11484C","-11485G","-11486G","-11487A","-11488T","-11489T","-11490C","-11491T","-11492A","-11493G","-11494C","-11495A","-11496G","-11497T","-11498A","-11499A","-11500A","-11501G","-11502A","-11503T","-11504A","-11505C","-11506T","-11507A","-11508G","-11509A","-11510G","-11511A","-11512T","-11513T","-11514G","-11515T","-11516T","-11517T","-11518A","-11519T","-11520T","-11521A","-11522T","-11523A","-11524T","-11525C","-11526T","-11527A","-11528A","-11529C","-11530A","-11531G","-11532C","-11533C","-11534T","-11535T","-11536G","-11537T","-11538G","-11539A","-11540A","-11541G","-11542A","-11543A","-11544G","-11545T","-11546G","-11547T","-11548T","-11549T","-11550C","-11551T","-11552C","-11553C","-11554T","-11555C","-11556G","-11557T","-11558T","-11559T","-11560G","-11561T","-11562C","-11563A","-11564A","-11565T","-11566C","-11567A","-11568T","-11569G","-11570T","-11571T","-11572A","-11573A","-11574T","-11575G","-11576T","-11577C","-11578T","-11579T","-11580T","-11581A","-11582A","-11583G","-11584A","-11585T","-11586A","-11587A","-11588G","-11589G","-11590T","-11591A","-11592G","-11593A","-11594C","-11595A","-11596A","-11597A","-11598T","-11599G","-11600T","-11601T","-11602T","-11603A","-11604T","-11605A","-11606G","-11607T","-11608A","-11609C","-11610T","-11611A","-11612A","-11613G","-11614A","-11615A","-11616T","-11617T","-11618G","-11619G","-11620G","-11621C","-11622A","-11623A","-11624A","-11625C","-11626A","-11627T","-11628A","-11629A","-11630G","-11631A","-11632C","-11633A","-11634T","-11635G","-11636T","-11637C","-11638A","-11639C","-11640A","-11641A","-11642A","-11643G","-11644A","-11645C","-11646C","-11647C","-11648T","-11649T","-11650T","-11651T","-11652T","-11653G","-11654T","-11655A","-11656T","-11657G","-11658T","-11659A","-11660T","-11661A","-11662A","-11663G","-11664T","-11665G","-11666T","-11667A","-11668G","-11669A","-11670A","-11671A","-11672T","-11673T","-11674A","-11675T","-11676A","-11677A","-11678C","-11679A","-11680T","-11681C","-11682C","-11683A","-11684T","-11685A","-11686G","-11687T","-11688T","-11689G","-11690G","-11691A","-11692T","-11693T","-11694C","-11695A","-11696C","-11697A","-11698T","-11699A","-11700G","-11701G","-11702T","-11703G","-11704T","-11705C","-11706C","-11707A","-11708A","-11709T","-11710C","-11711G","-11712G","-11713G","-11714A","-11715T","-11716C","-11717T","-11718C","-11719T","-11720C","-11721C","-11722A","-11723T","-11724C","-11725A","-11726T","-11727C","-11728G","-11729A","-11730G","-11731A","-11732T","-11733G","-11734A","-11735T","-11736T","-11737G","-11738A","-11739C","-11740G","-11741G","-11742C","-11743A","-11744T","-11745C","-11746T","-11747C","-11748C","-11749C","-11750C","-11751C","-11752T","-11753T","-11754C","-11755C","-11756T","-11757T","-11758T","-11759T","-11760T","-11761T","-11762A","-11763G","-11764T","-11765A","-11766G","-11767A","-11768T","-11769A","-11770T","-11771T","-11772T","-11773C","-11774A","-11775T","-11776C","-11777G","-11778T","-11779G","-11780T","-11781A","-11782A","-11783G","-11784A","-11785A","-11786T","-11787C","-11788A","-11789A","-11790T","-11791A","-11792T","-11793T","-11794A","-11795A","-11796T","-11797A","-11798T","-11799T","-11800T","-11801C","-11802T","-11803A","-11804A","-11805A","-11806G","-11807T","-11808A","-11809T","-11810C","-11811T","-11812G","-11813T","-11814G","-11815T","-11816A","-11817T","-11818A","-11819G","-11820C","-11821C","-11822T","-11823C","-11824T","-11825T","-11826T","-11827A","-11828T","-11829T","-11830T","-11831A","-11832C","-11833C","-11834A","-11835C","-11836A","-11837G","-11838C","-11839T","-11840C","-11841C","-11842A","-11843T","-11844A","-11845T","-11846T","-11847C","-11848C","-11849A","-11850A","-11851C","-11852A","-11853T","-11854G","-11855C","-11856A","-11857T","-11858T","-11859C","-11860C","-11861A","-11862C","-11863T","-11864A","-11865G","-11866A","-11867G","-11868G","-11869G","-11870A","-11871T","-11872A","-11873T","-11874C","-11875G","-11876A","-11877T","-11878A","-11879T","-11880C","-11881G","-11882C","-11883C","-11884G","-11885A","-11886A","-11887T","-11888G","-11889T","-11890C","-11891A","-11892T","-11893A","-11894T","-11895A","-11896C","-11897T","-11898C","-11899A","-11900A","-11901T","-11902T","-11903A","-11904G","-11905T","-11906A","-11907T","-11908A","-11909T","-11910G","-11911T","-11912T","-11913G","-11914G","-11915A","-11916G","-11917G","-11918A","-11919C","-11920A","-11921T","-11922C","-11923C","-11924G","-11925A","-11926G","-11927T","-11928T","-11929C","-11930A","-11931T","-11932T","-11933G","-11934T","-11935T","-11936T","-11937T","-11938C","-11939A","-11940A","-11941T","-11942A","-11943T","-11944C","-11945A","-11946A","-11947A","-11948G","-11949A","-11950G","-11951A","-11952T","-11953G","-11954G","-11955T","-11956T","-11957T","-11958C","-11959C","-11960T","-11961T","-11962A","-11963T","-11964C","-11965A","-11966T","-11967T","-11968T","-11969C","-11970T","-11971C","-11972C","-11973A","-11974T","-11975A","-11976G","-11977T","-11978G","-11979G","-11980T","-11981A","-11982C","-11983A","-11984A","-11985T","-11986A","-11987C","-11988T","-11989A","-11990C","-11991A","-11992C","-11993A","-11994T","-11995T","-11996A","-11997T","-11998T","-11999C","-12000C","-12001G","-12002T","-12003A","-12004C","-12005G","-12006G","-12007C","-12008T","-12009T","-12010T","-12011C","-12012C","-12013A","-12014T","-12015T","-12016C","-12017T","-12018C","-12019C","-12020A","-12021A","-12022A","-12023A","-12024A","-12025C","-12026A","-12027A","-12028T","-12029T","-12030T","-12031T","-12032A","-12033C","-12034C","-12035A","-12036A","-12037A","-12038T","-12039C","-12040T","-12041A","-12042A","-12043A","-12044T","-12045C","-12046T","-12047A","-12048C","-12049A","-12050T","-12051C","-12052T","-12053T","-12054T","-12055A","-12056T","-12057T","-12058G","-12059T","-12060A","-12061T","-12062C","-12063T","-12064A","-12065T","-12066A","-12067A","-12068T","-12069C","-12070A","-12071C","-12072T","-12073A","-12074T","-12075T","-12076T","-12077A","-12078G","-12079A","-12080T","-12081A","-12082A","-12083T","-12084C","-12085A","-12086G","-12087C","-12088C","-12089A","-12090T","-12091A","-12092A","-12093T","-12094T","-12095C","-12096C","-12097T","-12098C","-12099G","-12100A","-12101G","-12102T","-12103G","-12104C","-12105A","-12106A","-12107C","-12108A","-12109T","-12110G","-12111T","-12112T","-12113A","-12114G","-12115A","-12116T","-12117C","-12118G","-12119T","-12120C","-12121T","-12122A","-12123T","-12124A","-12125T","-12126A","-12127T","-12128G","-12129A","-12130A","-12131T","-12132A","-12133A","-12134G","-12135C","-12136C","-12137G","-12138T","-12139G","-12140T","-12141T","-12142A","-12143T","-12144C","-12145T","-12146A","-12147T","-12148T","-12149C","-12150C","-12151T","-12152T","-12153T","-12154C","-12155A","-12156T","-12157T","-12158A","-12159A","-12160C","-12161A","-12162A","-12163T","-12164T","-12165T","-12166A","-12167A","-12168C","-12169G","-12170A","-12171T","-12172G","-12173T","-12174C","-12175T","-12176A","-12177T","-12178A","-12179T","-12180C","-12181T","-12182A","-12183T","-12184A","-12185T","-12186G","-12187A","-12188G","-12189A","-12190T","-12191G","-12192A","-12193C","-12194T","-12195T","-12196A","-12197A","-12198T","-12199A","-12200T","-12201A","-12202A","-12203T","-12204A","-12205T","-12206T","-12207G","-12208A","-12209A","-12210G","-12211A","-12212G","-12213C","-12214T","-12215G","-12216T","-12217A","-12218C","-12219A","-12220A","-12221T","-12222A","-12223G","-12224T","-12225T","-12226T","-12227T","-12228T","-12229A","-12230T","-12231C","-12232T","-12233A","-12234T","-12235A","-12236G","-12237A","-12238A","G40242A","C40335T","G139582A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG023":["-222S","-223I","-224D","-225K","-226N","-227Y","-228C","-229T","-230A","-231L","-232Q","-233Y","-234Y","-235I","-236K","-237S","-238S","-239H","-240I","-241D","-242I","-243D","-244I","-245V","-246K","-247L","-248L","-249M","-250K","-251G","-252I","-253D","-254N","-255T","-256A","-257Y","-258S","-259Y","-260I","-261D","-262D","-263L","-264T","-265C","-266C","-267T","-268R","-269G","-270I","-271M","-272A","-273D","-274Y","-275L","-276N","-277S","-278D","-279Y","-280R","-281Y","-282N","-283K","-284D","-285V","-286D","-287L","-288D","-289L","-290V","-291K","-292L","-293F","-294L","-295E","-296N","-297G","-298K","-299P","-300Y","-301G","-302I","-303M","-304C","-305S","-306I","-307V","-308P","-309L","-310W","-311R","-312N","-313D","-314K","-315E","-316T","-317I","-318S","-319L","-320I","-321L","-322K","-323T","-324M","-325N","-326S","-327D","-328V","-329L","-330Q","-331H","-332I","-333L","-334I","-335E","-336Y","-337M","-338T","-339F","-340G","-341D","-342I","-343D","-344I","-345P","-346L","-347V","-348E","-349C","-350M","-351L","-352E","-353Y","-354G","-355A","-356V","-357V","-358N","-359K","-360E","-361A","-362I","-363H","-364R","-365Y","-366F","-367R","-368N","-369I","-370N","-371I","-372D","-373S","-374Y","-375T","-376M","-377K","-378Y","-379L","-380L","-381K","-382K","-383E","-384G","-385G","-386D","-387A","-388V","-389N","-390H","-391L","-392D","-393D","-394G","-395E","-396I","-397P","-398I","-399G","-400H","-401L","-402C","-403E","-404S","-405N","-406Y","-407G","-408C","-409Y","-410N","-411F","-412Y","-413T","-414Y","-415T","-416Y","-417K","-418K","-419G","-420L","-421C","-422D","-423M","-424S","-425Y","-426V","-427C","-428P","-429I","-430L","-431S","-432T","-433I","-434N","-435I","-436C","-437L","-438P","-439Y","-440L","-441K","-442D","-443I","-444N","-445M","-446I","-447D","-448K","-449R","-450G","-451E","-452T","-453L","-454L","-455H","-456K","-457A","-458V","-459R","-460Y","-461N","-462K","-463Q","-464S","-465L","-466V","-467S","-468L","-469L","-470L","-471E","-472S","-473G","-474S","-475D","-476V","-477N","-478I","-479R","-480S","-481N","-482N","-483G","-484Y","-485T","-486C","-487I","-488T","-489I","-490A","-491I","-492N","-493E","-494S","-495R","-496N","-497I","-498E","-499L","-500L","-501K","-502M","-503L","-504L","-505C","-506H","-507K","-508P","-509T","-510L","-511D","-512C","-513V","-514I","-515D","-516S","-517L","-518S","-519E","-520V","-521S","-522N","-523I","-524V","-525D"],"OPG058":["E34K"]},"labels":{"aa":"OPG023: -222S, -223I, -224D, -225K, -226N, -227Y, -228C, -229T, -230A, -231L, -232Q, -233Y, -234Y, -235I, -236K, -237S, -238S, -239H, -240I, -241D, -242I, -243D, -244I, -245V, -246K, -247L, -248L, -249M, -250K, -251G, -252I, -253D, -254N, -255T, -256A, -257Y, -258S, -259Y, -260I, -261D, -262D, -263L, -264T, -265C, -266C, -267T, -268R, -269G, -270I, -271M, -272A, -273D, -274Y, -275L, -276N, -277S, -278D, -279Y, -280R, -281Y, -282N, -283K, -284D, -285V, -286D, -287L, -288D, -289L, -290V, -291K, -292L, -293F, -294L, -295E, -296N, -297G, -298K, -299P, -300Y, -301G, -302I, -303M, -304C, -305S, -306I, -307V, -308P, -309L, -310W, -311R, -312N, -313D, -314K, -315E, -316T, -317I, -318S, -319L, -320I, -321L, -322K, -323T, -324M, -325N, -326S, -327D, -328V, -329L, -330Q, -331H, -332I, -333L, -334I, -335E, -336Y, -337M, -338T, -339F, -340G, -341D, -342I, -343D, -344I, -345P, -346L, -347V, -348E, -349C, -350M, -351L, -352E, -353Y, -354G, -355A, -356V, -357V, -358N, -359K, -360E, -361A, -362I, -363H, -364R, -365Y, -366F, -367R, -368N, -369I, -370N, -371I, -372D, -373S, -374Y, -375T, -376M, -377K, -378Y, -379L, -380L, -381K, -382K, -383E, -384G, -385G, -386D, -387A, -388V, -389N, -390H, -391L, -392D, -393D, -394G, -395E, -396I, -397P, -398I, -399G, -400H, -401L, -402C, -403E, -404S, -405N, -406Y, -407G, -408C, -409Y, -410N, -411F, -412Y, -413T, -414Y, -415T, -416Y, -417K, -418K, -419G, -420L, -421C, -422D, -423M, -424S, -425Y, -426V, -427C, -428P, -429I, -430L, -431S, -432T, -433I, -434N, -435I, -436C, -437L, -438P, -439Y, -440L, -441K, -442D, -443I, -444N, -445M, -446I, -447D, -448K, -449R, -450G, -451E, -452T, -453L, -454L, -455H, -456K, -457A, -458V, -459R, -460Y, -461N, -462K, -463Q, -464S, -465L, -466V, -467S, -468L, -469L, -470L, -471E, -472S, -473G, -474S, -475D, -476V, -477N, -478I, -479R, -480S, -481N, -482N, -483G, -484Y, -485T, -486C, -487I, -488T, -489I, -490A, -491I, -492N, -493E, -494S, -495R, -496N, -497I, -498E, -499L, -500L, -501K, -502M, -503L, -504L, -505C, -506H, -507K, -508P, -509T, -510L, -511D, -512C, -513V, -514I, -515D, -516S, -517L, -518S, -519E, -520V, -521S, -522N, -523I, -524V, -525D; OPG058: E34K"}},"children":[{"name":"OP642402","node_attrs":{"div":564,"accession":"OP642402","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"strain":{"value":"ANT-LDSP-ANT-MPX-24957C"},"date":{"value":"2022-09-12"},"strain_display":{"value":"Colombia/OP642402/2022-09-12"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G125388A","G126763A","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-"],"OPG145":["R481H"],"OPG148":["E260K"]},"labels":{"aa":"OPG145: R481H; OPG148: E260K"}}},{"name":"NODE_0000127","node_attrs":{"div":563,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C127609T"]}},"children":[{"name":"OP431400","node_attrs":{"div":566,"accession":"OP431400","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"strain":{"value":"ANT-LDSP-ANT-MPX-22751-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-17"},"strain_display":{"value":"Colombia/OP431400/2022-08-17"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G47482A","C60062T","G125388A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG080":["E653K"],"OPG145":["R481H"]},"labels":{"aa":"OPG080: E653K; OPG145: R481H"}}},{"name":"OP819950","node_attrs":{"div":565,"accession":"OP819950","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"strain":{"value":"MET_INS_MPX_0956_C"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-12"},"strain_display":{"value":"Colombia/OP819950/2022-10-12"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G144284A","C171808T","G196973-","A196974-","A196975-"],"OPG165":["D257N"],"OPG199":["S274L"]},"labels":{"aa":"OPG165: D257N; OPG199: S274L"}}},{"name":"OR035721","node_attrs":{"div":565,"accession":"OR035721","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/UZ_REGA_115"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035721/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C21324T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G180556A","T196712-","A196713-","T196714-"]}}},{"name":"OR086972","node_attrs":{"div":568,"accession":"OR086972","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/UZ_REGA_163/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR086972/2022-07-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G31180A","C142626T","G158549A","G159341A","C170750T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG163":["S142L"],"OPG185":["G142E"],"OPG198":["A238V"]},"labels":{"aa":"OPG163: S142L; OPG185: G142E; OPG198: A238V"}}}]}]}]},{"name":"NODE_0000128","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G175093A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179194A","-179195T","-179199C","-179208C","-179217C","-179226C","-179235C"],"OPG204":["D188N"]},"labels":{"aa":"OPG204: D188N","clade":"B.1.13"}},"children":[{"name":"OP536663","node_attrs":{"div":559,"accession":"OP536663","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"country":{"value":"USA"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV-USA-IL-IDPH-002"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-04"},"strain_display":{"value":"USA/OP536663/2022-08-04"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G119424A","G125452A","-179193T","-179196A","-179197T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG136":["S55L"],"OPG146":["S63L"]},"labels":{"aa":"OPG136: S55L; OPG146: S63L"}}},{"name":"NODE_0000129","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G22814A","G55162A","G137128A","G167910A","-179193T","-179196A","-179197T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG038":["H116Y"],"OPG074":["S655L"],"OPG193":["E193K"]},"labels":{"aa":"OPG038: H116Y; OPG074: S655L; OPG193: E193K"}},"children":[{"name":"OP536673","node_attrs":{"div":561,"accession":"OP536673","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"country":{"value":"USA"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV-USA-IL-IDPH-012"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"strain_display":{"value":"USA/OP536673/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-196615A","-196616A","-196617A"]}}},{"name":"NODE_0000130","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C118921T","A173316-","T173317-"],"OPG136":["D223N"]},"labels":{"aa":"OPG136: D223N"}},"children":[{"name":"OQ320456","node_attrs":{"div":562,"accession":"OQ320456","author":{"author":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y.","value":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV_USA_2022_KS0004"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ320456/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"OQ721921","node_attrs":{"div":563,"accession":"OQ721921","author":{"author":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y.","value":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV_USA_2022_KS0005"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721921/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C110297T","A173314-","T173315-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-"]}}}]}]},{"name":"NODE_0000131","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C132520T"]}},"children":[{"name":"OP257254","node_attrs":{"div":558,"accession":"OP257254","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"MpxV/human/USA/OH-UW-073812/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP257254/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179193T","-179196A","-179197T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR160418","node_attrs":{"div":565,"accession":"OR160418","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"country":{"value":"USA"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-052-0034/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-05-10"},"strain_display":{"value":"USA/OR160418/2023-05-10"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C27520T","G58883A","G99832A","G102186A","G129583A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G171410A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","A179194-","T179195-","C179199-","C179208-","C179217-","C179226-","C179235-","C182950T"],"OPG043":["A146T"],"OPG118":["D463N"],"OPG121":["E133K"],"OPG210":["S532L"]},"labels":{"aa":"OPG043: A146T; OPG118: D463N; OPG121: E133K; OPG210: S532L"}}},{"name":"NODE_0000132","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G165086A"]}},"children":[{"name":"OP536701","node_attrs":{"div":560,"accession":"OP536701","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"country":{"value":"USA"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV-USA-IL-IDPH-040"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-22"},"strain_display":{"value":"USA/OP536701/2022-06-22"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C169529T","-179193T","-179196A","-179197T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"OP820455","node_attrs":{"div":562,"accession":"OP820455","author":{"author":"Barbian,H.,Green,S.,Kunstman,K.,Araujo Perez,F.,Bobrovska,S.,Hayden,M.,Moore,N.","value":"Barbian,H.,Green,S.,Kunstman,K.,Araujo Perez,F.,Bobrovska,S.,Hayden,M.,Moore,N."},"country":{"value":"USA"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"hMpxV/Human/USA/IL-RIPHL-MPXV_10006/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-08"},"strain_display":{"value":"USA/OP820455/2022-08-08"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","C85055T","G142550A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G165904A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","A179194-","T179195-","C179199-","C179208-","C179217-","C179226-","C179235-","A196614-"],"OPG163":["D117N"]},"labels":{"aa":"OPG163: D117N"}}}]},{"name":"NODE_0000133","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C21383T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179199-","C179208-","C179217-","C179226-","C179235-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG037":["G351S"]},"labels":{"aa":"OPG037: G351S"}},"children":[{"name":"OQ319139","node_attrs":{"div":561,"accession":"OQ319139","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV/Germany/2022/ON/RKI681"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OQ319139/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C24584T","G27462A","G150551-","A150569-","T150570-","A150571-","T150572-","G150573-","A150574-","T150575-","G150576-","A152676-","T152686-","A179194-","T179195-"],"OPG040":["D299N"],"OPG043":["S165L"]},"labels":{"aa":"OPG040: D299N; OPG043: S165L"}}},{"name":"OQ773520","node_attrs":{"div":562,"accession":"OQ773520","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV/Germany/2022/ON/RKI901"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773520/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G85431A","C146446T","C147140T","C179265-","A179266-","T179267-"],"OPG106":["S23F"],"OPG170":["M111I"]},"labels":{"aa":"OPG106: S23F; OPG170: M111I"}}}]}]}]},{"name":"NODE_0000134","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G111029A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]},"labels":{"clade":"B.1.6"}},"children":[{"name":"OP320549","node_attrs":{"div":557,"accession":"OP320549","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"country":{"value":"Peru"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"LIM-INS-010"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-02"},"strain_display":{"value":"Peru/OP320549/2022-07-02"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{}}},{"name":"OP289783","node_attrs":{"div":557,"accession":"OP289783","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Mestanza,O.,Lope,P.,Nunez,A.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Mestanza,O.,Lope,P.,Nunez,A."},"country":{"value":"Peru"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"LIM-INS-003"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-27"},"strain_display":{"value":"Peru/OP289783/2022-06-27"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{}}},{"name":"OP289782","node_attrs":{"div":557,"accession":"OP289782","author":{"author":"Silva,I.,Jimenez,V.,Hurtado,V.,Barcena,L.","value":"Silva,I.,Jimenez,V.,Hurtado,V.,Barcena,L."},"country":{"value":"Peru"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"LIM-INS-001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-25"},"strain_display":{"value":"Peru/OP289782/2022-06-25"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-196615A","-196616A","-196617A"]}}},{"name":"OP431402","node_attrs":{"div":558,"accession":"OP431402","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"ANT-LDSP-ANT-MPX-22752-O"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-18"},"strain_display":{"value":"Colombia/OP431402/2022-08-18"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G15814A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP536765","node_attrs":{"div":559,"accession":"OP536765","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"9000387"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP536765/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G59112A","C87978T"]}}},{"name":"OQ197863","node_attrs":{"div":558,"accession":"OQ197863","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Rosales,A.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Rosales,A.,Mercado-Reyes,M.M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"DC_INS_MPX-1122-H"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-22"},"strain_display":{"value":"Colombia/OQ197863/2022-10-22"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C151204T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"]}}},{"name":"OQ348868","node_attrs":{"div":559,"accession":"OQ348868","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"country":{"value":"USA"},"institution":{"value":"CDPH, VRDL"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000120/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-20"},"strain_display":{"value":"USA/OQ348868/2022-09-20"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","G150364A","C166930T"],"OPG176":["E186K"],"OPG192":["S67L"]},"labels":{"aa":"OPG176: E186K; OPG192: S67L"}}},{"name":"OQ503831","node_attrs":{"div":561,"accession":"OQ503831","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00408/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-11"},"strain_display":{"value":"USA/OQ503831/2023-01-11"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","G10945A","G39515A","C44627T","G56276A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A196614-"],"OPG064":["M424I"]},"labels":{"aa":"OPG064: M424I"}}},{"name":"NODE_0000135","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G132863A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A181356-","T181357-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","A181366-","A181368-","A181369-","A181370-","T181371-","T181372-"]}},"children":[{"name":"OP642401","node_attrs":{"div":558,"accession":"OP642401","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"ANT-LDSP-ANT-MPX-24947E"},"date":{"value":"2022-09-12"},"strain_display":{"value":"Colombia/OP642401/2022-09-12"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C181355-","G181358-","C181365-","G181367-"]}}},{"name":"OQ696099","node_attrs":{"div":561,"accession":"OQ696099","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"ANT-LDSP-ANT-MPX-30518C"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-09"},"strain_display":{"value":"Colombia/OQ696099/2022-11-09"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G63811A","G167862A","C170130T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","-181356A","-181357T","-181359A","-181360A","-181361T","-181362T","-181363T","-181364T","-181366A","-181368A","-181369A","-181370A","-181371T","-181372T"],"OPG193":["D177N"]},"labels":{"aa":"OPG193: D177N"}}}]},{"name":"NODE_0000136","node_attrs":{"div":563,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C14098T","C84063T","G142493A","G151324A","C170573T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","C187332T"],"OPG163":["D98N"],"OPG198":["S179L"]},"labels":{"aa":"OPG163: D98N; OPG198: S179L"}},"children":[{"name":"OQ503815","node_attrs":{"div":565,"accession":"OQ503815","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00422/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-03"},"strain_display":{"value":"USA/OQ503815/2022-12-03"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G97749A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","G188726A"]}}},{"name":"OR499960","node_attrs":{"div":568,"accession":"OR499960","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00503/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-15"},"strain_display":{"value":"USA/OR499960/2023-03-15"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G6746A","C39266T","C63819T","G106927A","G138862A","G169213A","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG083":["V300I"],"OPG125":["T243M"],"OPG156":["S183F"]},"labels":{"aa":"OPG083: V300I; OPG125: T243M; OPG156: S183F"}}}]}]},{"name":"NODE_0000137","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-","C148268T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"ON755039","node_attrs":{"div":557,"accession":"ON755039","author":{"author":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O.","value":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O."},"country":{"value":"France"},"institution":{"value":"IRBA, D.DNRBC/D.2MI/U.BACT"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_IRBA22-11"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-19"},"strain_display":{"value":"France/ON755039/2022-05-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T133097-","T133098-","T133099-","T133100-","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"NODE_0000138","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G9963A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T"],"OPG021":["R126K"]},"labels":{"aa":"OPG021: R126K","clade":"B.1.19"}},"children":[{"name":"OP270026","node_attrs":{"div":558,"accession":"OP270026","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"MpxV/human/CAN/UN-NML-4017/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"strain_display":{"value":"Canada/OP270026/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-133101T","-133102T","-196615A","-196616A","-196617A"]}}},{"name":"OP838893","node_attrs":{"div":558,"accession":"OP838893","author":{"author":"Viscardi,M.,Cozzolino,L.,De Martinis,C.,Cardillo,L.,Fusco,G.","value":"Viscardi,M.,Cozzolino,L.,De Martinis,C.,Cardillo,L.,Fusco,G."},"country":{"value":"Italy"},"institution":{"value":"Istituto Zooprofilattico Sperimentale del Mezzogiorno, Hanimal Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"ID6821"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-21"},"strain_display":{"value":"Italy/OP838893/2022-06-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","T133100-","C133103-","G133104-","A133105-","A133106-","T133107-","T133108-","C133109-","A133110-","C133111-","G133112-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A157678-","A157679-","A157680-","A157681-","T157682-","T157683-","T157684-","T157685-","A157686-","A157687-","G157688-","C157689-","G157690-","A157691-","T157692-","G157693-","A157694-","T157695-","A157696-","T163214-","C163215-","T163216-","T163217-","A163218-","T163219-","A163220-","T163221-","A163417-","A163418-","T163419-","T163420-","C163421-","T163422-","T163423-","C163424-","C163425-","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","G174537-","A174538-","T174539-","G174540-","A174541-","A174542-","A180482-","T180483-","T180484-","A180485-","A180486-","A180487-","A180488-","A180489-","A181114-","T181115-","T181116-","C181117-","C181118-","T181119-","T181120-","A181121-","T181122-","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-"],"OPG159":["N124-","Y125-","N126-"],"OPG189":["N29-","S30-","S31-"]},"labels":{"aa":"OPG159: N124-, Y125-, N126-; OPG189: N29-, S30-, S31-"}}},{"name":"OR035726","node_attrs":{"div":560,"accession":"OR035726","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV/UZ_REGA_120"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035726/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C22739T","-133101T","-133102T","G133104A","G133231A","T137560-","G164487A"],"OPG038":["E141K"]},"labels":{"aa":"OPG038: E141K"}}},{"name":"OR086965","node_attrs":{"div":563,"accession":"OR086965","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV/UZ_REGA_156/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR086965/2022-07-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C71016T","G77415A","G133319A","C176069T","G181309A"],"OPG089":["S384L"]},"labels":{"aa":"OPG089: S384L"}}},{"name":"NODE_0000139","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-133101T","-133102T","G150003A","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"]}},"children":[{"name":"OP382486","node_attrs":{"div":562,"accession":"OP382486","author":{"author":"Colson,P.","value":"Colson,P."},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"hMPXV-IHU00009"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-07"},"strain_display":{"value":"France/OP382486/2022-07-07"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C38483T","C164272T","G175971A"],"OPG189":["R314C"],"OPG205":["E106K"]},"labels":{"aa":"OPG189: R314C; OPG205: E106K"}}},{"name":"OQ172215","node_attrs":{"div":563,"accession":"OQ172215","author":{"author":"Zeggagh,J.,Ferraris,O.,Salmona,M.,Tarantola,A.,Molina,J.M.,Delaugerre,C.","value":"Zeggagh,J.,Ferraris,O.,Salmona,M.,Tarantola,A.,Molina,J.M.,Delaugerre,C."},"country":{"value":"France"},"institution":{"value":"Hopital Saint Louis, Paris"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV-1047"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-07"},"strain_display":{"value":"France/OQ172215/2022-06-07"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A2591G","A31053G","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133171-","C133172-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T133639-","A150635-","A152676-","T152686-","T155897A","C173533A","A179077T","A179079T","A179081T","C179082T","A179083T","A179086T","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","T194619C","T194627G"],"OPG002":["F54S"],"OPG002_dup":["F54S","C57G"],"OPG047":["C48R"]},"labels":{"aa":"OPG002: F54S; OPG002_dup: F54S, C57G; OPG047: C48R"}}},{"name":"OQ427121","node_attrs":{"div":560,"accession":"OQ427121","author":{"author":"Gigante,C.,Cogswell,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Grenz,L.,Li,Y.","value":"Gigante,C.,Cogswell,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Grenz,L.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV_USA_2022_OR0008"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OQ427121/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","C150140T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"],"OPG176":["S111L"]},"labels":{"aa":"OPG176: S111L"}}},{"name":"OR095050","node_attrs":{"div":562,"accession":"OR095050","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV/UZ_REGA_232/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-12"},"strain_display":{"value":"Belgium/OR095050/2022-08-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G57033A","G77415A","G83609A","T133101-","T133102-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C196750-","T196751-","A196752-"]}}},{"name":"NODE_0000140","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A169944T","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C185326T","-196615A"],"OPG197":["E92V"],"OPG210":["S1324L"]},"labels":{"aa":"OPG197: E92V; OPG210: S1324L"}},"children":[{"name":"OP555643","node_attrs":{"div":562,"accession":"OP555643","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"Monkeypox/PT0572/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-05"},"strain_display":{"value":"Portugal/OP555643/2022-09-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","C55057T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-"],"OPG073":["E29K"]},"labels":{"aa":"OPG073: E29K"}}},{"name":"OQ159056","node_attrs":{"div":565,"accession":"OQ159056","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV/Germany/2022/ON/RKI661"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OQ159056/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C2652T","G9584A","C87741T","G98995A","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG002":["D34N"],"OPG118":["E184K"]},"labels":{"aa":"OPG002: D34N; OPG118: E184K"}}}]},{"name":"NODE_0000141","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C74417T"],"OPG094":["S213L"]},"labels":{"aa":"OPG094: S213L"}},"children":[{"name":"OP205108","node_attrs":{"div":560,"accession":"OP205108","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV_UK_2022_9000145"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-16"},"strain_display":{"value":"United Kingdom/OP205108/2022-06-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OP413717","node_attrs":{"div":560,"accession":"OP413717","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"9000353"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP413717/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OP555533","node_attrs":{"div":561,"accession":"OP555533","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"Monkeypox/PT0452/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-04"},"strain_display":{"value":"Portugal/OP555533/2022-08-04"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-609T","G610-","T611-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C177833T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP536782","node_attrs":{"div":560,"accession":"OP536782","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"9000406"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536782/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}}]}]}]}]},{"name":"NODE_0000142","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","C187620T"]}},"children":[{"name":"OR464209","node_attrs":{"div":560,"accession":"OR464209","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_USA_2022_TX0056"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR464209/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","C1015T","G63034A","G103173A","C166214T","G196195A","A196614-"],"OPG082":["S140L"]},"labels":{"aa":"OPG082: S140L"}}},{"name":"NODE_0000143","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G53326A","C164385T","-196615A"]},"labels":{"clade":"B.1.20"}},"children":[{"name":"OQ320441","node_attrs":{"div":559,"accession":"OQ320441","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV_USA_2022_TX0040"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ320441/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"]}}},{"name":"OQ427125","node_attrs":{"div":561,"accession":"OQ427125","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV_USA_2022_TX0044"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ427125/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G48645A","G130027A"],"OPG068":["E149K"]},"labels":{"aa":"OPG068: E149K"}}},{"name":"OQ721939","node_attrs":{"div":561,"accession":"OQ721939","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV_USA_2022_TN0016"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721939/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C76839T","G89916A","T133101-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG097":["D13N"]},"labels":{"aa":"OPG097: D13N"}}},{"name":"OR464211","node_attrs":{"div":564,"accession":"OR464211","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV_USA_2022_TX0058"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR464211/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C9389T","C70539T","C71059T","C118247T","G118657A","A136552-","T136553-","C136554-"],"OPG089":["A225V"],"OPG136":["P311S"],"OPG153":["D385-"]},"labels":{"aa":"OPG089: A225V; OPG136: P311S; OPG153: D385-"}}},{"name":"NODE_0000144","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T602-","T603-","T604-","T605-","T606-","T607-","-133102T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177398A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","A196610-","A196611-","A196612-","A196613-","A196614-","A196615-"]}},"children":[{"name":"OQ427126","node_attrs":{"div":562,"accession":"OQ427126","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV_USA_2022_TX0045"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"USA/OQ427126/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G36027A","C72221T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A"],"OPG055":["R353C"],"OPG092":["E243K"]},"labels":{"aa":"OPG055: R353C; OPG092: E243K"}}},{"name":"OQ918695","node_attrs":{"div":560,"accession":"OQ918695","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00484/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-07"},"strain_display":{"value":"USA/OQ918695/2023-02-07"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ644783","node_attrs":{"div":560,"accession":"OQ644783","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00477/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-17"},"strain_display":{"value":"USA/OQ644783/2023-01-17"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T179179-","A179180-"]}}},{"name":"NODE_0000145","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C177899T","T179179-","A179180-"]}},"children":[{"name":"OR499995","node_attrs":{"div":568,"accession":"OR499995","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00539/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-07-23"},"strain_display":{"value":"USA/OR499995/2023-07-23"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C15718T","C22349T","C23353T","C83753T","G98119A","C113363T","G119341A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG037":["E29K"],"OPG039":["D256N"],"OPG117":["E691K"],"OPG132":["D60N"],"OPG136":["R83C"]},"labels":{"aa":"OPG037: E29K; OPG039: D256N; OPG117: E691K; OPG132: D60N; OPG136: R83C"}}},{"name":"NODE_0000146","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A662-","G146690A","T196633-","T196635-"],"OPG170":["S30F"]},"labels":{"aa":"OPG170: S30F"}},"children":[{"name":"OR665164","node_attrs":{"div":565,"accession":"OR665164","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MpxV/human/USA/WA-UW-098659/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-09-XX"},"strain_display":{"value":"USA/OR665164/2023-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-602T","-662A","G141131A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C159608T","G163900-","A163901-","A163902-","T163903-","C163904-","A163905-","G168964A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A192393C","G192396A","A192402G","-196610A","-196633T","-196635T"],"OPG185":["S231F"],"OPG189":["E190-","S191-"]},"labels":{"aa":"OPG185: S231F; OPG189: E190-, S191-"}}},{"name":"OR499949","node_attrs":{"div":562,"accession":"OR499949","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00492/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-30"},"strain_display":{"value":"USA/OR499949/2023-03-30"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A196713-","T196714-","A196715-"]}}},{"name":"OR499956","node_attrs":{"div":562,"accession":"OR499956","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00499/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-04-30"},"strain_display":{"value":"USA/OR499956/2023-04-30"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C661-","C663-","C196634-"]}}}]},{"name":"NODE_0000147","node_attrs":{"div":563,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C20453T","T164946C"]}},"children":[{"name":"OR449306","node_attrs":{"div":563,"accession":"OR449306","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Germany/2023/RKI1020"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-07-XX"},"strain_display":{"value":"Germany/OR449306/2023-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-602T","-603T","-604T","-605T","-606T","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"]}}},{"name":"OR421480","node_attrs":{"div":563,"accession":"OR421480","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"country":{"value":"USA"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0023/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-05-07"},"strain_display":{"value":"USA/OR421480/2023-05-07"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"OR725698","node_attrs":{"div":567,"accession":"OR725698","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"country":{"value":"USA"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"hMpxV/USA/IL-RIPHL-052-0100/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-08-22"},"strain_display":{"value":"USA/OR725698/2023-08-22"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-604T","-605T","-606T","C105798T","G148126A","C174050T","C180618T"],"OPG209":["S34L"]},"labels":{"aa":"OPG209: S34L"}}},{"name":"OR500003","node_attrs":{"div":565,"accession":"OR500003","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00547/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-06-12"},"strain_display":{"value":"USA/OR500003/2023-06-12"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C2313T","G51378A","A140155T","A140156G"],"OPG002":["D147N"],"OPG159":["N130C"]},"labels":{"aa":"OPG002: D147N; OPG159: N130C"}}}]}]}]}]}]},{"name":"NODE_0000148","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C18133T","G67611A","G130231A","G159277A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T"],"OPG185":["E121K"]},"labels":{"aa":"OPG185: E121K","clade":"B.1.11"}},"children":[{"name":"OP169336","node_attrs":{"div":560,"accession":"OP169336","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MpxV/human/USA/WA-UW-070499/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OP169336/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OP440607","node_attrs":{"div":565,"accession":"OP440607","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00065/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"USA/OP440607/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G2143-","C2144-","T2145-","G2146-","A2147-","G2148-","A2149-","C2150-","C2151-","G2152-","G2153-","T2154-","A2155-","G2156-","T2157-","G2158-","G2159-","T2160-","C2161-","G2162-","T2163-","C2164-","C2165-","G2166-","A2167-","G2168-","T2169-","A2170-","C2171-","A2172-","C2173-","G2174-","A2175-","T2176-","G2177-","T2178-","G2179-","T2180-","C2181-","G2182-","T2183-","T2184-","G2185-","A2186-","C2187-","T2188-","G2189-","G2190-","A2191-","T2192-","A2193-","C2194-","A2195-","G2196-","G2197-","T2198-","T2199-","A2200-","A2201-","T2202-","T2203-","T2204-","C2205-","C2206-","A2207-","C2208-","A2209-","T2210-","C2211-","G2212-","A2213-","T2214-","A2215-","T2216-","A2217-","G2218-","T2219-","T2220-","A2221-","A2222-","A2223-","T2224-","G2225-","T2226-","A2227-","T2228-","T2229-","G2230-","C2231-","T2232-","G2233-","G2234-","T2235-","T2236-","A2237-","C2238-","G2239-","A2240-","C2241-","G2242-","G2243-","G2244-","T2245-","T2246-","C2247-","G2248-","C2249-","A2250-","T2251-","T2252-","T2253-","A2254-","T2255-","C2256-","T2257-","G2258-","T2259-","G2260-","G2261-","A2262-","A2263-","G2264-","A2265-","G2266-","A2267-","C2268-","G2269-","G2270-","T2271-","G2272-","T2273-","G2274-","A2275-","G2276-","A2277-","A2278-","T2279-","A2280-","T2281-","G2282-","T2283-","T2284-","C2285-","C2286-","G2287-","G2288-","G2289-","A2290-","C2291-","C2292-","A2293-","C2294-","A2295-","C2296-","G2297-","G2298-","A2299-","G2300-","A2301-","A2302-","C2303-","A2304-","G2305-","A2306-","T2307-","G2308-","A2309-","C2310-","G2311-","T2312-","C2313-","T2314-","C2315-","C2316-","G2317-","G2318-","T2319-","A2320-","G2321-","A2322-","C2323-","G2324-","T2325-","G2326-","T2327-","A2328-","T2329-","C2330-","C2331-","G2332-","G2333-","A2334-","T2335-","A2336-","C2337-","T2338-","C2339-","C2340-","G2341-","T2342-","A2343-","T2344-","C2345-","C2346-","T2347-","A2348-","T2349-","T2350-","C2351-","C2352-","A2353-","C2354-","A2355-","C2356-","T2357-","T2358-","T2359-","G2360-","T2361-","T2362-","T2363-","T2364-","A2365-","G2366-","A2367-","A2368-","A2369-","T2370-","A2371-","C2372-","A2373-","T2374-","G2375-","T2376-","T2377-","C2378-","T2379-","A2380-","C2381-","A2382-","C2383-","C2384-","C2385-","T2386-","G2387-","A2388-","T2389-","G2390-","C2391-","T2392-","C2393-","C2394-","T2395-","T2396-","T2397-","G2398-","A2399-","G2400-","A2401-","A2402-","G2403-","A2404-","C2405-","A2406-","A2407-","T2408-","A2409-","A2410-","T2411-","A2412-","T2413-","C2414-","C2415-","T2416-","G2417-","G2418-","A2419-","G2420-","A2421-","G2422-","C2423-","A2424-","T2425-","T2426-","C2427-","A2428-","C2429-","A2430-","G2431-","A2432-","T2433-","T2434-","C2435-","T2436-","A2437-","T2438-","T2439-","G2440-","T2441-","G2442-","A2443-","G2444-","T2445-","C2446-","G2447-","T2448-","G2449-","T2450-","T2451-","A2452-","C2453-","A2454-","C2455-","G2456-","A2457-","T2458-","C2459-","G2460-","C2461-","G2462-","T2463-","C2464-","T2465-","C2466-","T2467-","A2468-","C2469-","C2470-","T2471-","G2472-","A2473-","T2474-","T2475-","A2476-","C2477-","T2478-","A2479-","T2480-","C2481-","A2482-","C2483-","A2484-","T2485-","C2486-","T2487-","T2488-","C2489-","C2490-","G2491-","T2492-","T2493-","A2494-","C2495-","A2496-","A2497-","C2498-","T2499-","T2500-","A2501-","G2502-","A2503-","C2504-","A2505-","A2506-","G2507-","C2508-","C2509-","T2510-","G2511-","T2512-","A2513-","A2514-","A2515-","T2516-","G2517-","A2518-","T2519-","T2520-","A2521-","T2522-","T2523-","G2524-","T2525-","G2526-","A2527-","G2528-","A2529-","T2530-","G2531-","T2532-","A2533-","A2534-","A2535-","G2536-","G2537-","T2538-","A2539-","T2540-","C2541-","C2542-","G2543-","A2544-","A2545-","C2546-","C2547-","A2548-","C2549-","A2550-","C2551-","G2552-","G2553-","T2554-","G2555-","T2556-","A2557-","C2558-","A2559-","T2560-","T2561-","G2562-","T2563-","G2564-","T2565-","A2566-","T2567-","T2568-","A2569-","G2570-","T2571-","C2572-","T2573-","T2574-","G2575-","C2576-","T2577-","A2578-","T2579-","C2580-","A2581-","C2582-","A2583-","T2584-","A2585-","A2586-","T2587-","C2588-","T2589-","G2590-","A2591-","A2592-","A2593-","G2594-","C2595-","G2596-","T2597-","A2598-","A2599-","G2600-","T2601-","T2602-","C2603-","C2604-","C2605-","G2606-","G2607-","A2608-","G2609-","G2610-","A2611-","C2612-","A2613-","C2614-","G2615-","A2616-","T2617-","A2618-","G2619-","A2620-","C2621-","A2622-","A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","T2653-","T2654-","T2655-","A2656-","C2657-","A2658-","C2659-","T2660-","T2661-","T2662-","C2663-","C2664-","A2665-","T2666-","T2667-","G2668-","G2669-","A2670-","T2671-","G2672-","G2673-","T2674-","G2675-","C2676-","A2677-","T2678-","G2679-","T2680-","G2681-","G2682-","T2683-","G2684-","C2685-","T2686-","A2687-","T2688-","A2689-","T2690-","C2691-","T2692-","C2693-","T2694-","T2695-","C2696-","C2697-","G2698-","T2699-","T2700-","T2701-","A2702-","T2703-","T2704-","A2705-","T2706-","T2707-","A2708-","T2709-","A2710-","C2711-","A2712-","T2713-","G2714-","A2715-","G2716-","A2717-","G2718-","A2719-","A2720-","A2721-","C2722-","A2723-","A2724-","T2725-","A2726-","T2727-","A2728-","T2729-","A2730-","C2731-","G2732-","A2733-","G2734-","T2735-","A2736-","T2737-","A2738-","A2739-","T2740-","A2741-","C2742-","G3104A","C20236T","C21206T","C134898T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C167792T","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","T179244-","C194106T","G194468-","T194469-","A194470-","T194471-","T194472-","A194473-","T194474-","A194475-","C194476-","T194477-","C194478-","G194479-","T194480-","A194481-","T194482-","A194483-","T194484-","A194485-","T194486-","T194487-","G194488-","T194489-","T194490-","T194491-","C194492-","T194493-","C194494-","T194495-","C194496-","A194497-","T194498-","G194499-","T194500-","A194501-","T194502-","A194503-","A194504-","T194505-","A194506-","A194507-","T194508-","A194509-","A194510-","A194511-","C194512-","G194513-","G194514-","A194515-","A194516-","G194517-","A194518-","G194519-","A194520-","T194521-","A194522-","T194523-","A194524-","G194525-","C194526-","A194527-","C194528-","C194529-","A194530-","C194531-","A194532-","T194533-","G194534-","C194535-","A194536-","C194537-","C194538-","A194539-","T194540-","C194541-","C194542-","A194543-","A194544-","T194545-","G194546-","G194547-","A194548-","A194549-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","C194595-","G194596-","T194597-","G194598-","T194599-","C194600-","C194601-","T194602-","C194603-","C194604-","G194605-","G194606-","G194607-","A194608-","A194609-","C194610-","T194611-","T194612-","A194613-","C194614-","G194615-","C194616-","T194617-","T194618-","T194619-","C194620-","A194621-","G194622-","A194623-","T194624-","T194625-","A194626-","T194627-","G194628-","T194629-","G194630-","A194631-","T194632-","A194633-","G194634-","C194635-","A194636-","A194637-","G194638-","A194639-","C194640-","T194641-","A194642-","A194643-","T194644-","A194645-","C194646-","A194647-","C194648-","A194649-","A194650-","T194651-","G194652-","T194653-","A194654-","C194655-","A194656-","C194657-","C194658-","G194659-","T194660-","G194661-","T194662-","G194663-","G194664-","T194665-","T194666-","C194667-","G194668-","G194669-","A194670-","T194671-","A194672-","C194673-","C194674-","T194675-","T194676-","T194677-","A194678-","C194679-","A194680-","T194681-","C194682-","T194683-","C194684-","A194685-","C194686-","A194687-","A194688-","T194689-","A194690-","A194691-","T194692-","C194693-","A194694-","T194695-","T194696-","T194697-","A194698-","C194699-","A194700-","G194701-","G194702-","C194703-","T194704-","T194705-","G194706-","T194707-","C194708-","T194709-","A194710-","A194711-","G194712-","T194713-","T194714-","G194715-","T194716-","A194717-","A194718-","C194719-","G194720-","G194721-","A194722-","A194723-","G194724-","A194725-","T194726-","G194727-","T194728-","G194729-","A194730-","T194731-","A194732-","G194733-","T194734-","A194735-","A194736-","T194737-","C194738-","A194739-","G194740-","G194741-","T194742-","A194743-","G194744-","A194745-","G194746-","A194747-","C194748-","G194749-","C194750-","G194751-","A194752-","T194753-","C194754-","G194755-","T194756-","G194757-","T194758-","A194759-","A194760-","C194761-","A194762-","C194763-","G194764-","A194765-","C194766-","T194767-","C194768-","A194769-","C194770-","A194771-","A194772-","T194773-","A194774-","G194775-","A194776-","A194777-","T194778-","C194779-","T194780-","G194781-","T194782-","G194783-","A194784-","A194785-","T194786-","G194787-","C194788-","T194789-","C194790-","T194791-","C194792-","C194793-","A194794-","G194795-","G194796-","A194797-","T194798-","A194799-","T194800-","T194801-","A194802-","T194803-","T194804-","G194805-","T194806-","C194807-","T194808-","T194809-","C194810-","T194811-","C194812-","A194813-","A194814-","A194815-","G194816-","G194817-","A194818-","G194819-","C194820-","A194821-","T194822-","C194823-","A194824-","G194825-","G194826-","G194827-","T194828-","G194829-","T194830-","A194831-","G194832-","A194833-","A194834-","C194835-","A194836-","T194837-","G194838-","T194839-","A194840-","T194841-","T194842-","T194843-","C194844-","T194845-","A194846-","A194847-","A194848-","A194849-","C194850-","A194851-","A194852-","A194853-","G194854-","T194855-","G194856-","T194857-","G194858-","G194859-","A194860-","A194861-","T194862-","A194863-","G194864-","G194865-","A194866-","T194867-","A194868-","C194869-","G194870-","G194871-","A194872-","G194873-","T194874-","A194875-","T194876-","C194877-","C194878-","G194879-","G194880-","A194881-","T194882-","A194883-","C194884-","A194885-","C194886-","G194887-","T194888-","C194889-","T194890-","A194891-","C194892-","C194893-","G194894-","G194895-","A194896-","G194897-","A194898-","C194899-","G194900-","T194901-","C194902-","A194903-","T194904-","C194905-","T194906-","G194907-","T194908-","T194909-","C194910-","T194911-","C194912-","C194913-","G194914-","T194915-","G194916-","T194917-","G194918-","G194919-","T194920-","C194921-","C194922-","C194923-","G194924-","G194925-","A194926-","A194927-","C194928-","A194929-","T194930-","A194931-","T194932-","T194933-","C194934-","T194935-","C194936-","A194937-","C194938-","A194939-","C194940-","C194941-","G194942-","T194943-","C194944-","T194945-","C194946-","T194947-","T194948-","C194949-","C194950-","A194951-","C194952-","A194953-","G194954-","A194955-","T194956-","A194957-","A194958-","A194959-","T194960-","G194961-","C194962-","G194963-","A194964-","A194965-","C194966-","C194967-","C194968-","G194969-","T194970-","C194971-","G194972-","T194973-","A194974-","A194975-","C194976-","C194977-","A194978-","G194979-","C194980-","A194981-","A194982-","T194983-","A194984-","C194985-","A194986-","T194987-","T194988-","T194989-","A194990-","A194991-","C194992-","T194993-","A194994-","T194995-","A194996-","T194997-","C194998-","G194999-","A195000-","T195001-","G195002-","T195003-","G195004-","G195005-","A195006-","A195007-","A195008-","T195009-","T195010-","A195011-","A195012-","C195013-","C195014-","T195015-","G195016-","T195017-","A195018-","T195019-","C195020-","C195021-","A195022-","G195023-","T195024-","C195025-","A195026-","A195027-","C195028-","G195029-","A195030-","C195031-","A195032-","C195033-","A195034-","T195035-","C195036-","G195037-","T195038-","G195039-","T195040-","A195041-","C195042-","T195043-","C195044-","G195045-","G195046-","A195047-","C195048-","G195049-","A195050-","C195051-","C195052-","A195053-","C195054-","T195055-","A195056-","C195057-","C195058-","G195059-","G195060-","T195061-","C195062-","T195063-","C195064-","A195065-","G195066-","C195067-"],"OPG002":["V4-","L5-","Y6-","S7-","Y8-","I9-","L10-","F11-","L12-","S13-","C14-","I15-","I16-","I17-","N18-","G19-","R20-","D21-","I22-","A23-","P24-","H25-","A26-","P27-","S28-","N29-","G30-","K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-","C47-","P48-","P49-","G50-","T51-","Y52-","A53-","F54-","R55-","L56-","C57-","D58-","S59-","K60-","T61-","N62-","T63-","Q64-","C65-","T66-","P67-","C68-","G69-","S70-","D71-","T72-","F73-","T74-","S75-","H76-","N77-","N78-","H79-","L80-","Q81-","A82-","C83-","L84-","S85-","C86-","N87-","G88-","R89-","C90-","D91-","S92-","N93-","Q94-","V95-","E96-","T97-","R98-","S99-","C100-","N101-","T102-","T103-","H104-","N105-","R106-","I107-","C108-","E109-","C110-","S111-","P112-","G113-","Y114-","Y115-","C116-","L117-","L118-","K119-","G120-","A121-","S122-","G123-","C124-","R125-","T126-","C127-","I128-","S129-","K130-","T131-","K132-","C133-","G134-","I135-","G136-","Y137-","G138-","V139-","S140-","G141-","Y142-","T143-","S144-","T145-","G146-","D147-","V148-","I149-","C150-","S151-","P152-","C153-","G154-","P155-","G156-","T157-","Y158-","S159-","H160-","T161-","V162-","S163-","S164-","T165-","D166-","K167-","C168-","E169-","P170-","V171-","V172-","T173-","S174-","N175-","T176-","F177-","N178-","Y179-","I180-","D181-","V182-","E183-","I184-","N185-","L186-","Y187-","P188-","V189-","N190-","D191-","T192-","S193-","C194-","T195-","R196-","T197-","T198-","T199-","T200-","G201-","L202-","S203-"],"OPG002_dup":["V4-","L5-","Y6-","S7-","Y8-","I9-","L10-","F11-","L12-","S13-","C14-","I15-","I16-","I17-","N18-","G19-","R20-","D21-","I22-","A23-","P24-","H25-","A26-","P27-","S28-","N29-","G30-","K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-","C47-","P48-","P49-","G50-","T51-","Y52-","A53-","F54-","R55-","L56-","C57-","D58-","S59-","K60-","T61-","N62-","T63-","Q64-","C65-","T66-","P67-","C68-","G69-","S70-","D71-","T72-","F73-","T74-","S75-","H76-","N77-","N78-","H79-","L80-","Q81-","A82-","C83-","L84-","S85-","C86-","N87-","G88-","R89-","C90-","D91-","S92-","N93-","Q94-","V95-","E96-","T97-","R98-","S99-","C100-","N101-","T102-","T103-","H104-","N105-","R106-","I107-","C108-","E109-","C110-","S111-","P112-","G113-","Y114-","Y115-","C116-","L117-","L118-","K119-","G120-","A121-","S122-","G123-","C124-","R125-","T126-","C127-","I128-","S129-","K130-","T131-","K132-","C133-","G134-","I135-","G136-","Y137-","G138-","V139-","S140-","G141-","Y142-","T143-","S144-","T145-","G146-","D147-","V148-","I149-","C150-","S151-","P152-","C153-","G154-","P155-","G156-","T157-","Y158-","S159-","H160-","T161-","V162-","S163-","S164-","T165-","D166-","K167-","C168-","E169-","P170-","V171-","V172-","T173-","S174-","N175-","T176-","F177-","N178-","Y179-","I180-","D181-","V182-","E183-","I184-","N185-","L186-","Y187-","P188-","V189-","N190-","D191-","T192-","S193-","C194-","T195-","R196-","T197-","T198-","T199-","T200-","G201-","L202-","S203-"],"OPG003":["H502Y"],"OPG003_dup":["H502Y"],"OPG035":["D57N"],"OPG037":["D410N"]},"labels":{"aa":"OPG002: V4-, L5-, Y6-, S7-, Y8-, I9-, L10-, F11-, L12-, S13-, C14-, I15-, I16-, I17-, N18-, G19-, R20-, D21-, I22-, A23-, P24-, H25-, A26-, P27-, S28-, N29-, G30-, K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-, C47-, P48-, P49-, G50-, T51-, Y52-, A53-, F54-, R55-, L56-, C57-, D58-, S59-, K60-, T61-, N62-, T63-, Q64-, C65-, T66-, P67-, C68-, G69-, S70-, D71-, T72-, F73-, T74-, S75-, H76-, N77-, N78-, H79-, L80-, Q81-, A82-, C83-, L84-, S85-, C86-, N87-, G88-, R89-, C90-, D91-, S92-, N93-, Q94-, V95-, E96-, T97-, R98-, S99-, C100-, N101-, T102-, T103-, H104-, N105-, R106-, I107-, C108-, E109-, C110-, S111-, P112-, G113-, Y114-, Y115-, C116-, L117-, L118-, K119-, G120-, A121-, S122-, G123-, C124-, R125-, T126-, C127-, I128-, S129-, K130-, T131-, K132-, C133-, G134-, I135-, G136-, Y137-, G138-, V139-, S140-, G141-, Y142-, T143-, S144-, T145-, G146-, D147-, V148-, I149-, C150-, S151-, P152-, C153-, G154-, P155-, G156-, T157-, Y158-, S159-, H160-, T161-, V162-, S163-, S164-, T165-, D166-, K167-, C168-, E169-, P170-, V171-, V172-, T173-, S174-, N175-, T176-, F177-, N178-, Y179-, I180-, D181-, V182-, E183-, I184-, N185-, L186-, Y187-, P188-, V189-, N190-, D191-, T192-, S193-, C194-, T195-, R196-, T197-, T198-, T199-, T200-, G201-, L202-, S203-; OPG002_dup: V4-, L5-, Y6-, S7-, Y8-, I9-, L10-, F11-, L12-, S13-, C14-, I15-, I16-, I17-, N18-, G19-, R20-, D21-, I22-, A23-, P24-, H25-, A26-, P27-, S28-, N29-, G30-, K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-, C47-, P48-, P49-, G50-, T51-, Y52-, A53-, F54-, R55-, L56-, C57-, D58-, S59-, K60-, T61-, N62-, T63-, Q64-, C65-, T66-, P67-, C68-, G69-, S70-, D71-, T72-, F73-, T74-, S75-, H76-, N77-, N78-, H79-, L80-, Q81-, A82-, C83-, L84-, S85-, C86-, N87-, G88-, R89-, C90-, D91-, S92-, N93-, Q94-, V95-, E96-, T97-, R98-, S99-, C100-, N101-, T102-, T103-, H104-, N105-, R106-, I107-, C108-, E109-, C110-, S111-, P112-, G113-, Y114-, Y115-, C116-, L117-, L118-, K119-, G120-, A121-, S122-, G123-, C124-, R125-, T126-, C127-, I128-, S129-, K130-, T131-, K132-, C133-, G134-, I135-, G136-, Y137-, G138-, V139-, S140-, G141-, Y142-, T143-, S144-, T145-, G146-, D147-, V148-, I149-, C150-, S151-, P152-, C153-, G154-, P155-, G156-, T157-, Y158-, S159-, H160-, T161-, V162-, S163-, S164-, T165-, D166-, K167-, C168-, E169-, P170-, V171-, V172-, T173-, S174-, N175-, T176-, F177-, N178-, Y179-, I180-, D181-, V182-, E183-, I184-, N185-, L186-, Y187-, P188-, V189-, N190-, D191-, T192-, S193-, C194-, T195-, R196-, T197-, T198-, T199-, T200-, G201-, L202-, S203-; OPG003: H502Y; OPG003_dup: H502Y; OPG035: D57N; OPG037: D410N"}}},{"name":"OP390178","node_attrs":{"div":560,"accession":"OP390178","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"country":{"value":"Colombia"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MAG-UNIMOL-MPX-292982-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-20"},"strain_display":{"value":"Colombia/OP390178/2022-08-20"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP555545","node_attrs":{"div":560,"accession":"OP555545","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"Monkeypox/PT0466/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-05"},"strain_display":{"value":"Portugal/OP555545/2022-08-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-"]}}},{"name":"OP536709","node_attrs":{"div":561,"accession":"OP536709","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"country":{"value":"USA"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV-USA-IL-IDPH-048"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-23"},"strain_display":{"value":"USA/OP536709/2022-06-23"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","T48717A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG068":["L173I"]},"labels":{"aa":"OPG068: L173I"}}},{"name":"OP524006","node_attrs":{"div":561,"accession":"OP524006","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV/Germany/2022/RKI404"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP524006/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","G182634A","-196615A"],"OPG210":["D427N"]},"labels":{"aa":"OPG210: D427N"}}},{"name":"OP879738","node_attrs":{"div":560,"accession":"OP879738","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"country":{"value":"USA"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"NJ-MPXV-020-rep2"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-06"},"strain_display":{"value":"USA/OP879738/2022-07-06"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-"]}}},{"name":"OP819960","node_attrs":{"div":563,"accession":"OP819960","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"SAN_INS_MPX_0973_L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-17"},"strain_display":{"value":"Colombia/OP819960/2022-10-17"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["A19748-","G19749-","G19750-","C19751-","G19752-","T19753-","G27840A","C64404T","C96810T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG034":["T87-","P88-"],"OPG043":["S39F"],"OPG083":["D105N"]},"labels":{"aa":"OPG034: T87-, P88-; OPG043: S39F; OPG083: D105N"}}},{"name":"OP743993","node_attrs":{"div":563,"accession":"OP743993","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MpxV/human/USA/WA-UW-094603/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OP743993/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","G52594A","C89777T","G176818A","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG110":["P49L"],"OPG205":["R388Q"]},"labels":{"aa":"OPG110: P49L; OPG205: R388Q"}}},{"name":"OP693656","node_attrs":{"div":562,"accession":"OP693656","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"CUN_INS_MPX_0751_C"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-10"},"strain_display":{"value":"Colombia/OP693656/2022-09-10"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C33832T","C42036T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG052":["R55Q"]},"labels":{"aa":"OPG052: R55Q"}}},{"name":"OP920682","node_attrs":{"div":562,"accession":"OP920682","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00344/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-09"},"strain_display":{"value":"USA/OP920682/2022-11-09"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","G39327A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177273A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","-196615A"],"OPG057":["A290V"],"OPG205":["D540N"]},"labels":{"aa":"OPG057: A290V; OPG205: D540N"}}},{"name":"OQ427115","node_attrs":{"div":563,"accession":"OQ427115","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV_USA_2022_NY0040"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ427115/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C2446T","G126646A","C160354T","-179194A","-179195T","-179196A","-179197T","-179198A","G194764A"],"OPG148":["E221K"]},"labels":{"aa":"OPG148: E221K"}}},{"name":"OR035719","node_attrs":{"div":563,"accession":"OR035719","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV/UZ_REGA_113"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035719/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T133102-","C142797T","C167995T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G189258A"],"OPG164":["S7L"],"OPG193":["S221F"]},"labels":{"aa":"OPG164: S7L; OPG193: S221F"}}},{"name":"OQ957072","node_attrs":{"div":563,"accession":"OQ957072","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"ANT-LDSP-ANT-MPX-3668E"},"date":{"value":"2023-02-16"},"strain_display":{"value":"Colombia/OQ957072/2023-02-16"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C35308T","G71777A","C120979T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG054":["R230H"],"OPG138":["D52N"]},"labels":{"aa":"OPG054: R230H; OPG138: D52N"}}},{"name":"OQ696092","node_attrs":{"div":564,"accession":"OQ696092","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"ANT-LDSP-ANT-MPX-29706O"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-03"},"strain_display":{"value":"Colombia/OQ696092/2022-11-03"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G17023A","G74462A","C80742T","G113382A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","T196988-","A196989-","A196990-"],"OPG029":["S16F"],"OPG094":["R228K"],"OPG104":["R93Q"]},"labels":{"aa":"OPG029: S16F; OPG094: R228K; OPG104: R93Q"}}},{"name":"OR095053","node_attrs":{"div":560,"accession":"OR095053","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV/UZ_REGA_235/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-12"},"strain_display":{"value":"Belgium/OR095053/2022-08-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR464206","node_attrs":{"div":563,"accession":"OR464206","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV_USA_2022_TN0020"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR464206/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","G19458A","G74374A","-179194A","-179195T","-179196A","-179197T","-179198A","C185455T","-196615A"],"OPG034":["S183L"],"OPG094":["E199K"],"OPG210":["S1367L"]},"labels":{"aa":"OPG034: S183L; OPG094: E199K; OPG210: S1367L"}}}]},{"name":"NODE_0000149","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G36617A","C159779T"],"OPG055":["S156L"],"OPG185":["S288L"]},"labels":{"aa":"OPG055: S156L; OPG185: S288L","clade":"B.1.14"}},"children":[{"name":"ON959133","node_attrs":{"div":558,"accession":"ON959133","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV_USA_2022_NY002"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/ON959133/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"]}}},{"name":"ON694342","node_attrs":{"div":558,"accession":"ON694342","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/RKI011"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/ON694342/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP378704","node_attrs":{"div":561,"accession":"OP378704","author":{"author":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y.","value":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV_USA_2022_TX0010"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP378704/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C8552T","C8597T","G46179A","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A","-196616A"],"OPG065":["S102L"]},"labels":{"aa":"OPG065: S102L"}}},{"name":"OP355563","node_attrs":{"div":558,"accession":"OP355563","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/ON/RKI302"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP355563/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","A188351-"]}}},{"name":"OP626108","node_attrs":{"div":560,"accession":"OP626108","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/RKI470"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OP626108/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G53788A","G107868A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG126":["S88F"]},"labels":{"aa":"OPG126: S88F"}}},{"name":"OP837350","node_attrs":{"div":559,"accession":"OP837350","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/RKI588"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OP837350/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C84008T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OQ274887","node_attrs":{"div":558,"accession":"OQ274887","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/ON/RKI668"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ274887/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A152676-","T152686-"]}}},{"name":"OR035646","node_attrs":{"div":562,"accession":"OR035646","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/UZ_REGA_40"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR035646/2022-07-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C22880T","G158617A","C170573T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C183790T"],"OPG038":["E94K"],"OPG198":["S179L"],"OPG210":["S812L"]},"labels":{"aa":"OPG038: E94K; OPG198: S179L; OPG210: S812L"}}},{"name":"OR086995","node_attrs":{"div":559,"accession":"OR086995","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/UZ_REGA_186/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-03"},"strain_display":{"value":"Belgium/OR086995/2022-08-03"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G146441A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG170":["S113F"]},"labels":{"aa":"OPG170: S113F"}}},{"name":"OX009124","node_attrs":{"div":560,"accession":"OX009124","author":{"author":"Pettke,A.,Filen,F.,Asgeirsson,H.,Glans,H.,Widgren,K.,Muradrasoli,S.,Helgesson,S.,Karlberg,M.L.,Walai,N.,Bjerkner,A.,Gourle,H.,Lindsjo,O.K.,Sonden,K.","value":"Pettke,A.,Filen,F.,Asgeirsson,H.,Glans,H.,Widgren,K.,Muradrasoli,S.,Helgesson,S.,Karlberg,M.L.,Walai,N.,Bjerkner,A.,Gourle,H.,Lindsjo,O.K.,Sonden,K."},"country":{"value":"Sweden"},"institution":{"value":"Public Health Agency of Sweden, Unit for Laboratory Development and Technology Transfer , Folkhalsomyndigheten, 171 82 Solna"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"Lesion"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-22"},"strain_display":{"value":"Sweden/OX009124/2022-05-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T602-","T603-","T604-","T605-","T606-","A8055-","A28529-","A28530-","T47054-","T76087-","T88836-","A91705-","A92907-","T103367-","T104687-","T148344A","A148345T","A151680-","A162904-","T163342-","T163597-","A170728-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG044":["K147-"],"OPG113":["I393-"],"OPG178":["T58-"],"OPG188":["K437-"],"OPG189":["F4-"],"OPG198":["K231-"]},"labels":{"aa":"OPG044: K147-; OPG113: I393-; OPG178: T58-; OPG188: K437-; OPG189: F4-; OPG198: K231-"}}},{"name":"NODE_0000150","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G28021A"]}},"children":[{"name":"OR026629","node_attrs":{"div":560,"accession":"OR026629","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"country":{"value":"USA"},"institution":{"value":"Utah Public Health Laboratory, Utah Public Health Laboratory Infectious Disease submission group"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200382/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-09"},"strain_display":{"value":"USA/OR026629/2022-09-09"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C148666T"],"OPG174":["A244T"]},"labels":{"aa":"OPG174: A244T"}}},{"name":"NODE_0000151","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G181818A"],"OPG210":["A155T"]},"labels":{"aa":"OPG210: A155T"}},"children":[{"name":"OP539922","node_attrs":{"div":561,"accession":"OP539922","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00137/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-09"},"strain_display":{"value":"USA/OP539922/2022-08-09"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G109793A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G168211-","G168212-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP743362","node_attrs":{"div":561,"accession":"OP743362","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"country":{"value":"USA"},"institution":{"value":"Utah Public Health Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200104/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-21"},"strain_display":{"value":"USA/OP743362/2022-07-21"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A19512C"],"OPG034":["I165R"]},"labels":{"aa":"OPG034: I165R"}}}]}]},{"name":"NODE_0000152","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G171270A","-196615A","-196616T"],"OPG199":["D95N"]},"labels":{"aa":"OPG199: D95N"}},"children":[{"name":"OP382492","node_attrs":{"div":560,"accession":"OP382492","author":{"author":"Colson,P.","value":"Colson,P."},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"hMPXV-IHU00015"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-22"},"strain_display":{"value":"France/OP382492/2022-07-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G161913A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196856-","A196857-","A196858-"]}}},{"name":"OP494266","node_attrs":{"div":559,"accession":"OP494266","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/ON/RKI320"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP494266/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OP605553","node_attrs":{"div":559,"accession":"OP605553","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"Slovenia-MPXV-10-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Slovenia/OP605553/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","T196950-","A196951-","A196952-"]}}},{"name":"OP555644","node_attrs":{"div":561,"accession":"OP555644","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"Monkeypox/PT0573/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-06"},"strain_display":{"value":"Portugal/OP555644/2022-09-06"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","C93713T","G158549A"]}}},{"name":"OP555562","node_attrs":{"div":559,"accession":"OP555562","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"Monkeypox/PT0486/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-09"},"strain_display":{"value":"Portugal/OP555562/2022-08-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000153","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G34308A"],"OPG053":["S128L"]},"labels":{"aa":"OPG053: S128L","clade":"B.1.4"}},"children":[{"name":"ON880519","node_attrs":{"div":558,"accession":"ON880519","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-2833/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-13"},"strain_display":{"value":"Canada/ON880519/2022-05-13"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T85846C"],"OPG107":["M112T"]},"labels":{"aa":"OPG107: M112T"}}},{"name":"OP390177","node_attrs":{"div":558,"accession":"OP390177","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"country":{"value":"Colombia"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"ATL-UNIMOL-MPX-292896-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-13"},"strain_display":{"value":"Colombia/OP390177/2022-08-13"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C176447T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"NODE_0000154","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C10672T","G112481A","G163626A"],"OPG022":["E63K"]},"labels":{"aa":"OPG022: E63K"}},"children":[{"name":"OR126132","node_attrs":{"div":564,"accession":"OR126132","author":{"author":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C.","value":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C."},"country":{"value":"Spain"},"institution":{"value":"Hospital Ramon y Cajal, Microbiology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"HRYC_MPXV002"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-23"},"strain_display":{"value":"Spain/OR126132/2023-03-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G6376A","G11924A","G21674A","A87705G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C190834T"],"OPG016":["S142L"],"OPG023":["S326L"],"OPG037":["L254F"]},"labels":{"aa":"OPG016: S142L; OPG023: S326L; OPG037: L254F"}}},{"name":"NODE_0000155","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G144478A"]}},"children":[{"name":"ON880511","node_attrs":{"div":561,"accession":"ON880511","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-3214/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Canada/ON880511/2022-05-30"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"OP752106","node_attrs":{"div":564,"accession":"OP752106","author":{"author":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Morrison,S.S.,Desch,M.,Knipe,K.,Weigand,M.R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Morrison,S.S.,Desch,M.,Knipe,K.,Weigand,M.R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPXV_USA_2022_FL0025"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OP752106/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C57339T","T173285-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","G176716A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","G185991A"],"OPG075":["E54K"],"OPG205":["G354D"],"OPG210":["D1546N"]},"labels":{"aa":"OPG075: E54K; OPG205: G354D; OPG210: D1546N"}}},{"name":"OR759176","node_attrs":{"div":564,"accession":"OR759176","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"hMpxV/Canada/ON-PHOL088/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759176/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","C128534T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C151626T","G170076A"],"OPG178":["Q40*"]},"labels":{"aa":"OPG178: Q40*"}}},{"name":"OR759160","node_attrs":{"div":561,"accession":"OR759160","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"hMpxV/Canada/ON-PHOL064/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759160/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}}]}]},{"name":"NODE_0000156","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C24995T","G85774A","G148427A","G189258A"],"OPG040":["D162N"],"OPG107":["R88K"]},"labels":{"aa":"OPG040: D162N; OPG107: R88K"}},"children":[{"name":"ON983163","node_attrs":{"div":561,"accession":"ON983163","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-3532/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-07"},"strain_display":{"value":"Canada/ON983163/2022-06-07"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"ON803414","node_attrs":{"div":561,"accession":"ON803414","author":{"author":"Knox,N.,Hole,D.,Duggan,A.,Yadav,C.,Haidl,E.,Chapel,M.,Graham,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Hagan,M.,Griffiths,E.,Leung,A.,Safronetz,D.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Knox,N.,Hole,D.,Duggan,A.,Yadav,C.,Haidl,E.,Chapel,M.,Graham,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Hagan,M.,Griffiths,E.,Leung,A.,Safronetz,D.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-2930/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-21"},"strain_display":{"value":"Canada/ON803414/2022-05-21"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP279035","node_attrs":{"div":561,"accession":"OP279035","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-4103/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-04"},"strain_display":{"value":"Canada/OP279035/2022-07-04"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ427147","node_attrs":{"div":562,"accession":"OQ427147","author":{"author":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPXV_USA_2022_IL0006"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OQ427147/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G131810A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG151":["D963N"]},"labels":{"aa":"OPG151: D963N"}}},{"name":"NODE_0000157","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G45236A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP279043","node_attrs":{"div":562,"accession":"OP279043","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-4140/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-30"},"strain_display":{"value":"Canada/OP279043/2022-06-30"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OP415246","node_attrs":{"div":563,"accession":"OP415246","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPX_J6xzTO_9000286"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415246/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G174962A"],"OPG204":["R144K"]},"labels":{"aa":"OPG204: R144K"}}}]}]},{"name":"NODE_0000158","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G36259A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G174543A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}},"children":[{"name":"OP626135","node_attrs":{"div":562,"accession":"OP626135","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPXV/Germany/2022/RKI496"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP626135/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C40251T","C154472T","G167517A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"],"OPG058":["D62N"],"OPG181":["H21Y"],"OPG193":["E62K"]},"labels":{"aa":"OPG058: D62N; OPG181: H21Y; OPG193: E62K"}}},{"name":"OQ547900","node_attrs":{"div":561,"accession":"OQ547900","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"country":{"value":"USA"},"institution":{"value":"CDPH, VRDL"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000185/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-21"},"strain_display":{"value":"USA/OQ547900/2022-12-21"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T6976-","G92733A","C177720T"],"OPG113":["E335K"],"OPG205":["R689C"]},"labels":{"aa":"OPG113: E335K; OPG205: R689C"}}},{"name":"NODE_0000159","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C25967T"],"OPG042":["W377*"]},"labels":{"aa":"OPG042: W377*"}},"children":[{"name":"OP442553","node_attrs":{"div":561,"accession":"OP442553","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00086/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"USA/OP442553/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C188775T"]}}},{"name":"NODE_0000160","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C172792T"]}},"children":[{"name":"OP920681","node_attrs":{"div":562,"accession":"OP920681","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00343/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-10"},"strain_display":{"value":"USA/OP920681/2022-11-10"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A763-","A764-","T765-","C97805T"],"OPG117":["P586L"]},"labels":{"aa":"OPG117: P586L"}}},{"name":"NODE_0000161","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","A150591-","T150592-","A150595-","T150596-","A150597-","T150598-","A150600-","T150601-","A163469T"],"OPG189":["E46V"]},"labels":{"aa":"OPG189: E46V"}},"children":[{"name":"OQ503786","node_attrs":{"div":570,"accession":"OQ503786","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00452/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-12"},"strain_display":{"value":"USA/OQ503786/2022-10-12"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G70435A","C125412T","C141442T","C141511T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G158709A","T172792C","G175698A","G176439A"],"OPG145":["S489L"],"OPG161":["S114L","S137F"],"OPG205":["D15N","D262N"]},"labels":{"aa":"OPG145: S489L; OPG161: S114L, S137F; OPG205: D15N, D262N"}}},{"name":"OQ503765","node_attrs":{"div":562,"accession":"OQ503765","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/USA/WA-UW-091026/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ503765/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]}]}]}]}]},{"name":"NODE_0000162","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G5595A","C191615T"],"OPG015":["Q188*"],"OPG015_dup":["Q188*"]},"labels":{"aa":"OPG015: Q188*; OPG015_dup: Q188*","clade":"B.1.8"}},"children":[{"name":"OP215224","node_attrs":{"div":557,"accession":"OP215224","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/RKI235"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP215224/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000163","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G161296A","-179188T","-179189A","C196308T"],"OPG001_dup":["S225L"]},"labels":{"aa":"OPG001_dup: S225L"}},"children":[{"name":"OP331337","node_attrs":{"div":558,"accession":"OP331337","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV_UK_2022_9000183"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-29"},"strain_display":{"value":"United Kingdom/OP331337/2022-06-29"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G902A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG001":["S225L"]},"labels":{"aa":"OPG001: S225L"}}},{"name":"OP555609","node_attrs":{"div":560,"accession":"OP555609","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"Monkeypox/PT0538/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-23"},"strain_display":{"value":"Portugal/OP555609/2022-08-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","G902A","C25269T","G25692A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179188-","A179189-"],"OPG001":["S225L"]},"labels":{"aa":"OPG001: S225L"}}},{"name":"OP863250","node_attrs":{"div":561,"accession":"OP863250","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/ON/RKI600"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP863250/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G89716A","G128858A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","G181052-","C186220T"],"OPG110":["E29K"],"OPG209":["G179-"],"OPG210":["A1622V"]},"labels":{"aa":"OPG110: E29K; OPG209: G179-; OPG210: A1622V"}}},{"name":"OR030928","node_attrs":{"div":559,"accession":"OR030928","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/UZ_REGA_17"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-19"},"strain_display":{"value":"Belgium/OR030928/2022-07-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G902A","C68981T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG001":["S225L"],"OPG087":["S42L"]},"labels":{"aa":"OPG001: S225L; OPG087: S42L"}}},{"name":"OR449625","node_attrs":{"div":558,"accession":"OR449625","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/ON/RKI912"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449625/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150562-","A150563-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"NODE_0000164","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C80545T","T196308C"],"OPG001_dup":["L225S"],"OPG103":["S182L"]},"labels":{"aa":"OPG001_dup: L225S; OPG103: S182L"}},"children":[{"name":"ON929089","node_attrs":{"div":559,"accession":"ON929089","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/RKI134"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/ON929089/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179188-","A179189-"]}}},{"name":"NODE_0000165","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G102614A","C170573T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG122":["V63I"],"OPG198":["S179L"]},"labels":{"aa":"OPG122: V63I; OPG198: S179L"}},"children":[{"name":"OR035714","node_attrs":{"div":561,"accession":"OR035714","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/UZ_REGA_108"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035714/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OR095062","node_attrs":{"div":562,"accession":"OR095062","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/UZ_REGA_244/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-16"},"strain_display":{"value":"Belgium/OR095062/2022-08-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C62305T"]}}}]}]}]},{"name":"NODE_0000166","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G78034A","C80111T"],"OPG099":["D124N"]},"labels":{"aa":"OPG099: D124N"}},"children":[{"name":"ON622718","node_attrs":{"div":560,"accession":"ON622718","author":{"author":"Martinez-Puchol,S.,Coello,A.,Bordoy,A.E.,Soler,L.,Panisello,D.,Gonzalez-Gomez,S.,Clara,G.,Paris de Leon,A.,Not,A.,Hernandez,A.,Bofill-Mas,S.,Saludes,V.,Blanco,I.,Martro,E.,Cardona,P.-J.","value":"Martinez-Puchol,S.,Coello,A.,Bordoy,A.E.,Soler,L.,Panisello,D.,Gonzalez-Gomez,S.,Clara,G.,Paris de Leon,A.,Not,A.,Hernandez,A.,Bofill-Mas,S.,Saludes,V.,Blanco,I.,Martro,E.,Cardona,P.-J."},"country":{"value":"Spain"},"institution":{"value":"Microbiology, Hospital Universitari Germans Trias i Pujol, Spain"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/ES0001/HUGTiP/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-20"},"strain_display":{"value":"Spain/ON622718/2022-05-20"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C14113-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T139150C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","-196615A","-196616A"],"OPG156":["Q87R"]},"labels":{"aa":"OPG156: Q87R"}}},{"name":"NODE_0000167","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G22643A","G63811A"],"OPG038":["H173Y"]},"labels":{"aa":"OPG038: H173Y"}},"children":[{"name":"OP378705","node_attrs":{"div":561,"accession":"OP378705","author":{"author":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y.","value":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV_USA_2022_TX0011"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP378705/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP459214","node_attrs":{"div":561,"accession":"OP459214","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"ANT-LDSP-ANT-MPX-23631-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-30"},"strain_display":{"value":"Colombia/OP459214/2022-08-30"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP642374","node_attrs":{"div":562,"accession":"OP642374","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"ANT-LDSP-ANT-MPX-24722-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-08"},"strain_display":{"value":"Colombia/OP642374/2022-09-08"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G168759A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG195":["R177K"]},"labels":{"aa":"OPG195: R177K"}}},{"name":"OP626136","node_attrs":{"div":563,"accession":"OP626136","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/RKI497"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP626136/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C64635T","G141114A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG083":["A28T"],"OPG161":["E5K"]},"labels":{"aa":"OPG083: A28T; OPG161: E5K"}}},{"name":"OQ320513","node_attrs":{"div":565,"accession":"OQ320513","author":{"author":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y.","value":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV_USA_2022_FL0009"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ320513/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G4038A","A39081T","C67289T","G73790A","T133102-","A173284-","T173285-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C193172T"],"OPG057":["I372N"],"OPG085":["E415K"],"OPG094":["G4E"]},"labels":{"aa":"OPG057: I372N; OPG085: E415K; OPG094: G4E"}}},{"name":"OQ557957","node_attrs":{"div":563,"accession":"OQ557957","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV_USA_2022_TX0047"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OQ557957/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C84485T","C127215T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG149":["S7L"]},"labels":{"aa":"OPG149: S7L"}}},{"name":"OQ721943","node_attrs":{"div":564,"accession":"OQ721943","author":{"author":"Gigante,C.,Segaloff,H.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Florek,K.,Li,Y.","value":"Gigante,C.,Segaloff,H.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Florek,K.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV_USA_2022_WI0002"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721943/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G22108A","G93387A","C144233T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"],"OPG037":["S109L"],"OPG113":["E553K"],"OPG165":["Q240*"]},"labels":{"aa":"OPG037: S109L; OPG113: E553K; OPG165: Q240*"}}},{"name":"OR759149","node_attrs":{"div":565,"accession":"OR759149","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"hMpxV/Canada/ON-PHOL055/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759149/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C8555T","G95862A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168089T","G181674A","-196615A"],"OPG116":["A168T"],"OPG210":["E107K"]},"labels":{"aa":"OPG116: A168T; OPG210: E107K"}}},{"name":"NODE_0000168","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T119985C"]}},"children":[{"name":"OP415254","node_attrs":{"div":563,"accession":"OP415254","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPX_imBNaw_9000300"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415254/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G189258A"]}}},{"name":"OP597796","node_attrs":{"div":562,"accession":"OP597796","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"country":{"value":"USA"},"institution":{"value":"Minnesota Department of Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MN-MDH-MPXV_0022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-18"},"strain_display":{"value":"USA/OP597796/2022-07-18"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}}]}]}]}]},{"name":"NODE_0000169","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C89906T","G94798A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG110":["S92F"],"OPG115":["E47K"]},"labels":{"aa":"OPG110: S92F; OPG115: E47K","clade":"B.1.10"}},"children":[{"name":"ON720848","node_attrs":{"div":559,"accession":"ON720848","author":{"author":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"country":{"value":"Spain"},"institution":{"value":"Microbial Genomics, Hospital General Universitario Gregorio Marañón, Madrid, Spain"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MpxV/Spain/MD-HGUGM-6513479/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-27"},"strain_display":{"value":"Spain/ON720848/2022-05-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A327-","T605-","T606-","A1697-","T4296-","T6587-","T6588-","T7253-","G7724-","T8017-","A8036-","T8499-","T9514-","A9869-","T10502-","A10914-","T11188-","C11749-","T11761-","T12121-","A15754-","A17087-","T18866-","A19360-","T20663-","A21081-","T21975-","T24678-","T25853-","T26099-","C27002-","A27114-","C27799-","A28529-","A28530-","T32194-","T33414-","G35949-","T37982-","T39131-","T39866-","T41744-","T42990-","C43014-","G43200-","A43443-","T44120-","T44738-","G46762-","T48675-","A49134-","G49833-","A51022-","A52765-","A54968-","A55124-","T55560-","T56040-","T57075-","A57277-","A58650-","T61749-","A62041-","T63628-","A64728-","A64935-","A65535-","A65967-","T66783-","A66843-","A67164-","C68466-","T68481-","C68899-","G69145-","A69744-","T69768-","A71254-","G71359-","T75833-","A76072-","T76084-","T76085-","A76153-","A76154-","A76890-","A77260-","T77803-","T78062-","A79042-","A79181-","G79217-","C79533T","A79787-","G80950-","C82482-","T84846-","T88095-","T88836-","T88941-","A89106-","T90646-","T91129-","T91370-","A91583-","A91705-","T94795-","A95341-","A95574-","G95742-","G95818-","A97351-","A97480-","A97501-","A97699-","A98683-","T101452-","G101515-","T102437-","T103367-","T103368-","T104279-","T105360-","T106596-","T108598-","A113921-","T113951-","C114431-","T114518-","T114755-","T115127-","G115801-","A116014-","C116494-","T116963-","T121121-","T121122-","G121269-","C121546-","T124022-","T124751-","A125249-","A126568-","T126682-","A126715-","A127250-","A127754-","A132023-","A132024-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133639-","T136780-","T137886-","A143045-","G143363-","T143478-","A144230-","T146131-","A148000-","A149727-","A150340-","T150538-","T150539-","A150635-","T150864-","A151490-","A151508-","G151545-","A152676-","T152686-","A153358-","A153424-","A153517-","T154862-","T155424-","C156607-","C156608-","A157997-","T163498-","T163597-","A163957-","A165461-","A166740-","G167640-","A167967-","T168120-","A170728-","T170758-","T170903-","T170904-","T172087-","T172667-","G179036-","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","A179551-","A179950-","T180905-","G181052-","A181253-","C183534-","A183780-","T187080-","A190935-","A191015-","G191519-","A196613-","A196614-","T196888-","T197183-"],"OPG015_dup":["G156-"],"OPG016":["T176-"],"OPG019":["G49-"],"OPG021":["N95-"],"OPG023":["G385-"],"OPG043":["G53-"],"OPG044":["K147-"],"OPG066":["P223-"],"OPG068":["L159-","D545-"],"OPG070":["N145-"],"OPG074":["K523-"],"OPG084":["K3-","K272-","R416-"],"OPG085":["F457-"],"OPG087":["L15-","G97-"],"OPG090":["K26-"],"OPG096":["L83-"],"OPG098":["S121-"],"OPG099":["F47-"],"OPG100":["F19-"],"OPG102":["K33-"],"OPG104":["P24-"],"OPG109":["K206-"],"OPG111":["F128-"],"OPG112":["S42-"],"OPG115":["S46-"],"OPG116":["K72-"],"OPG117":["K435-","N478-","R551-"],"OPG118":["I80-"],"OPG122":["Y4-"],"OPG123":["K569-"],"OPG133":["K394-"],"OPG134":["E18-","P249-"],"OPG139":["P34-"],"OPG145":["F26-","F269-","K435-"],"OPG148":["I195-","F233-"],"OPG149":["K19-"],"OPG151":["K1034-"],"OPG164":["R90-"],"OPG165":["M239-"],"OPG172":["I192-"],"OPG175":["N96-"],"OPG176":["K178-"],"OPG178":["D13-"],"OPG180":["K223-","K276-"],"OPG181":["F151-"],"OPG189":["L56-","K209-"],"OPG190":["N114-"],"OPG192":["K4-"],"OPG193":["G103-","F263-"],"OPG198":["K231-"],"OPG208":["I96-"],"OPG209":["L130-"],"OPG210":["P727-"]},"labels":{"aa":"OPG015_dup: G156-; OPG016: T176-; OPG019: G49-; OPG021: N95-; OPG023: G385-; OPG043: G53-; OPG044: K147-; OPG066: P223-; OPG068: L159-, D545-; OPG070: N145-; OPG074: K523-; OPG084: K3-, K272-, R416-; OPG085: F457-; OPG087: L15-, G97-; OPG090: K26-; OPG096: L83-; OPG098: S121-; OPG099: F47-; OPG100: F19-; OPG102: K33-; OPG104: P24-; OPG109: K206-; OPG111: F128-; OPG112: S42-; OPG115: S46-; OPG116: K72-; OPG117: K435-, N478-, R551-; OPG118: I80-; OPG122: Y4-; OPG123: K569-; OPG133: K394-; OPG134: E18-, P249-; OPG139: P34-; OPG145: F26-, F269-, K435-; OPG148: I195-, F233-; OPG149: K19-; OPG151: K1034-; OPG164: R90-; OPG165: M239-; OPG172: I192-; OPG175: N96-; OPG176: K178-; OPG178: D13-; OPG180: K223-, K276-; OPG181: F151-; OPG189: L56-, K209-; OPG190: N114-; OPG192: K4-; OPG193: G103-, F263-; OPG198: K231-; OPG208: I96-; OPG209: L130-; OPG210: P727-"}}},{"name":"OP245334","node_attrs":{"div":560,"accession":"OP245334","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPX/PT0081/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-23"},"strain_display":{"value":"Portugal/OP245334/2022-07-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-609T","G610-","T611-","C120237T","G126047A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A196619-","T196620-"],"OPG148":["R21K"]},"labels":{"aa":"OPG148: R21K"}}},{"name":"OP205110","node_attrs":{"div":558,"accession":"OP205110","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV_UK_2022_9000147"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-14"},"strain_display":{"value":"United Kingdom/OP205110/2022-06-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T"]}}},{"name":"OP205091","node_attrs":{"div":558,"accession":"OP205091","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV_UK_2022_9000103"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-13"},"strain_display":{"value":"United Kingdom/OP205091/2022-06-13"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T"]}}},{"name":"OP450985","node_attrs":{"div":558,"accession":"OP450985","author":{"author":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y.","value":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV_USA_2022_TX0019"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP450985/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","A136552-","T136553-","C136554-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-196615A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OQ581847","node_attrs":{"div":571,"accession":"OQ581847","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"country":{"value":"Spain"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0005b/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-01"},"strain_display":{"value":"Spain/OQ581847/2022-07-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A43453G","A66769C","T88735A","G90070A","C101656T","G104325A","C121681T","G127869A","G132490A","T133095A","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T139779C","G140866T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C151204T","T176743A","-179217C","-179218A","-179219T","-179220T"],"OPG063":["L79P"],"OPG085":["V588G"],"OPG109":["E238V"],"OPG110":["D147N"],"OPG123":["A249V"],"OPG150":["G31R"],"OPG160":["S70Y"],"OPG205":["L363*"]},"labels":{"aa":"OPG063: L79P; OPG085: V588G; OPG109: E238V; OPG110: D147N; OPG123: A249V; OPG150: G31R; OPG160: S70Y; OPG205: L363*"}}},{"name":"OR264420","node_attrs":{"div":559,"accession":"OR264420","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"45_B"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-10"},"strain_display":{"value":"Australia/OR264420/2022-07-10"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["G63147A","-179218A","-179219T","-179220T","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"NODE_0000170","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C150831T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-"]}},"children":[{"name":"ON959143","node_attrs":{"div":560,"accession":"ON959143","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O."},"country":{"value":"Finland"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPX-96/Finland/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-16"},"strain_display":{"value":"Finland/ON959143/2022-06-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","C188491T"]}}},{"name":"OP382489","node_attrs":{"div":560,"accession":"OP382489","author":{"author":"Colson,P.","value":"Colson,P."},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"hMPXV-IHU00012"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-19"},"strain_display":{"value":"France/OP382489/2022-07-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G109437A","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G150603-","A150604-","T150605-","A150606-","T150607-","G150608-","A150609-","T150610-","G150611-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T"],"OPG129":["S523L"],"OPG153":["D384-","D385-"]},"labels":{"aa":"OPG129: S523L; OPG153: D384-, D385-"}}},{"name":"OP879740","node_attrs":{"div":559,"accession":"OP879740","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"country":{"value":"USA"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"NJ-MPXV-022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-06"},"strain_display":{"value":"USA/OP879740/2022-07-06"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}}]},{"name":"NODE_0000171","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C33103T","C45605T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG049":["E17K"]},"labels":{"aa":"OPG049: E17K"}},"children":[{"name":"OP215226","node_attrs":{"div":561,"accession":"OP215226","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Germany/2022/RKI241"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP215226/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G47702A"]}}},{"name":"OP594193","node_attrs":{"div":560,"accession":"OP594193","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Germany/2022/RKI429"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP594193/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OQ773504","node_attrs":{"div":560,"accession":"OQ773504","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Germany/2022/ON/RKI885"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773504/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A41660-","A41661-","T41662-","T41663-","T41664-","G41665-","T41666-","T41667-","T41668-","T41669-","A41670-","C41671-","T41672-","C41673-","T41674-","A41675-","T41676-","A41677-","G150551-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG061":["Y70-","R71-","V72-","K73-","Q74-","I75-"]},"labels":{"aa":"OPG061: Y70-, R71-, V72-, K73-, Q74-, I75-"}}}]},{"name":"NODE_0000172","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C20879T","C60094T"],"OPG036":["M62I"],"OPG080":["R642K"]},"labels":{"aa":"OPG036: M62I; OPG080: R642K"}},"children":[{"name":"OP415264","node_attrs":{"div":561,"accession":"OP415264","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPX_Tga3e9_9000325"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415264/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G86904A","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T"]}}},{"name":"OR035722","node_attrs":{"div":561,"accession":"OR035722","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/UZ_REGA_116"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035722/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G149818A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","T196712-","A196713-","T196714-"],"OPG176":["D4N"]},"labels":{"aa":"OPG176: D4N"}}},{"name":"OR464215","node_attrs":{"div":560,"accession":"OR464215","author":{"author":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y.","value":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV_USA_2022_DC0006"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OR464215/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}}]},{"name":"NODE_0000173","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G50672A"],"OPG070":["R28K"]},"labels":{"aa":"OPG070: R28K"}},"children":[{"name":"OP689664","node_attrs":{"div":561,"accession":"OP689664","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Germany/2022/ON/RKI511"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"Germany/OP689664/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C13624T","C43472T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG063":["E73K"]},"labels":{"aa":"OPG063: E73K"}}},{"name":"NODE_0000174","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C49265T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T"]}},"children":[{"name":"OP536764","node_attrs":{"div":561,"accession":"OP536764","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"9000385"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536764/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","C100007T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"],"OPG118":["S521F"]},"labels":{"aa":"OPG118: S521F"}}},{"name":"OP459217","node_attrs":{"div":563,"accession":"OP459217","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"ANT-LDSP-ANT-MPX-23654-O"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-30"},"strain_display":{"value":"Colombia/OP459217/2022-08-30"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C113965T","G150800A","C152191T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG133":["E578K"]},"labels":{"aa":"OPG133: E578K"}}},{"name":"OP623593","node_attrs":{"div":562,"accession":"OP623593","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"country":{"value":"Colombia"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"BOL-UNIMOL-MPX-293264-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-17"},"strain_display":{"value":"Colombia/OP623593/2022-09-17"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["A1701-","C1702-","T1703-","C126654T","G149746A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","T196852-","G196853-","T196854-"],"OPG175":["C102Y"]},"labels":{"aa":"OPG175: C102Y"}}},{"name":"OQ261703","node_attrs":{"div":562,"accession":"OQ261703","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"ANT-LDSP-ANT-MPX-28297C"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-13"},"strain_display":{"value":"Colombia/OQ261703/2022-10-13"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G39515A","T113536C","T196854-","A196855-","A196856-"],"OPG132":["D2G"]},"labels":{"aa":"OPG132: D2G"}}},{"name":"OP959057","node_attrs":{"div":561,"accession":"OP959057","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"country":{"value":"Colombia"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"SUC-UNIMOL-MPX-293401-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-10"},"strain_display":{"value":"Colombia/OP959057/2022-11-10"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G23118A"]}}}]}]}]},{"name":"NODE_0000175","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G1302A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C182950T"],"OPG001":["L92F"],"OPG210":["S532L"]},"labels":{"aa":"OPG001: L92F; OPG210: S532L","clade":"B.1.12"}},"children":[{"name":"OQ773485","node_attrs":{"div":557,"accession":"OQ773485","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV/Germany/2022/ON/RKI866"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773485/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150563-","T150564-","G150565-","A150566-","T150567-","-179189A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"]}}},{"name":"NODE_0000176","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G78328A","C195908T"],"OPG001_dup":["L92F"]},"labels":{"aa":"OPG001_dup: L92F"}},"children":[{"name":"OP524001","node_attrs":{"div":558,"accession":"OP524001","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV/Germany/2022/RKI399"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP524001/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000177","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C57550T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP415207","node_attrs":{"div":559,"accession":"OP415207","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPX_BhVKjm_9000233"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415207/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OP415206","node_attrs":{"div":559,"accession":"OP415206","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPX_BhVKjm_9000232"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415206/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000178","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A1302G","G111084A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"],"OPG001":["F92L"]},"labels":{"aa":"OPG001: F92L"}},"children":[{"name":"OP013003","node_attrs":{"div":558,"accession":"OP013003","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MpxV/human/CAN/UN-NML-3276/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-31"},"strain_display":{"value":"Canada/OP013003/2022-05-31"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"ON880548","node_attrs":{"div":558,"accession":"ON880548","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MpxV/human/CAN/UN-NML-3448/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-03"},"strain_display":{"value":"Canada/ON880548/2022-06-03"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"OQ121959","node_attrs":{"div":566,"accession":"OQ121959","author":{"author":"Barbian,H.,Green,S.,Kunstman,K.,Araujo Perez,F.,Bobrovska,S.,Hayden,M.,Moore,N.","value":"Barbian,H.,Green,S.,Kunstman,K.,Araujo Perez,F.,Bobrovska,S.,Hayden,M.,Moore,N."},"country":{"value":"USA"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"hMpxV/Human/USA/IL-RIPHL-MPXV_10015/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-18"},"strain_display":{"value":"USA/OQ121959/2022-10-18"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","G4859A","C24077T","C24231T","G67582A","C88319T","G97405A","C101656T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G165506A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C192351T","A196614-"],"OPG015":["S433L"],"OPG015_dup":["S433L"],"OPG085":["S317L"],"OPG109":["A377T"],"OPG117":["E453K"],"OPG190":["E129K"]},"labels":{"aa":"OPG015: S433L; OPG015_dup: S433L; OPG085: S317L; OPG109: A377T; OPG117: E453K; OPG190: E129K"}}},{"name":"NODE_0000179","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G121510A"]}},"children":[{"name":"ON880540","node_attrs":{"div":559,"accession":"ON880540","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MpxV/human/CAN/UN-NML-3342/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-01"},"strain_display":{"value":"Canada/ON880540/2022-06-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"OR759170","node_attrs":{"div":564,"accession":"OR759170","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"hMpxV/Canada/ON-PHOL082/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759170/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","G10060A","G37022A","C132410T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G154793A","C180055T","-196615A"],"OPG055":["S21F"],"OPG181":["D128N"]},"labels":{"aa":"OPG055: S21F; OPG181: D128N"}}}]},{"name":"NODE_0000180","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G98233A","G98455A","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179235C"],"OPG117":["D729N"],"OPG118":["G4K"]},"labels":{"aa":"OPG117: D729N; OPG118: G4K"}},"children":[{"name":"ON880413","node_attrs":{"div":561,"accession":"ON880413","author":{"author":"Coletti,T.M.,Ghilardi,F.,khan,M.J.,Claro,I.M.,Valenca,I.N.,Faria,N.R.,Sabino,E.C.","value":"Coletti,T.M.,Ghilardi,F.,khan,M.J.,Claro,I.M.,Valenca,I.N.,Faria,N.R.,Sabino,E.C."},"country":{"value":"Brazil"},"institution":{"value":"Imperial College London, School of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPX/BR0002/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-14"},"strain_display":{"value":"Brazil/ON880413/2022-06-14"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C76334T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG097":["R181K"]},"labels":{"aa":"OPG097: R181K"}}},{"name":"NODE_0000181","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G98456A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T"]}},"children":[{"name":"OP171925","node_attrs":{"div":563,"accession":"OP171925","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"country":{"value":"USA"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV22/human/USA-NE-75"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-25"},"strain_display":{"value":"USA/OP171925/2022-07-25"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C10484T","A61974G","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"OP270022","node_attrs":{"div":564,"accession":"OP270022","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MpxV/human/CAN/UN-NML-3972/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-04"},"strain_display":{"value":"Canada/OP270022/2022-07-04"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","G3361A","C152970T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G181349A","C193849T"],"OPG003":["S416L"],"OPG003_dup":["S416L"]},"labels":{"aa":"OPG003: S416L; OPG003_dup: S416L"}}},{"name":"OR209309","node_attrs":{"div":564,"accession":"OR209309","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV_USA_2022_TN0019"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR209309/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C93601T","C94418T","T133101-","T133102-","C136029T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["A624V"],"OPG114":["E84K"]},"labels":{"aa":"OPG113: A624V; OPG114: E84K"}}},{"name":"OR464195","node_attrs":{"div":562,"accession":"OR464195","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV_USA_2022_NY0047"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OR464195/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T67849G","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","C179235-"],"OPG085":["N228T"]},"labels":{"aa":"OPG085: N228T"}}},{"name":"NODE_0000182","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G153910A","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-"],"OPG180":["E407K"]},"labels":{"aa":"OPG180: E407K"}},"children":[{"name":"OR759180","node_attrs":{"div":566,"accession":"OR759180","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"hMpxV/Canada/ON-PHOL092/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759180/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","C16209T","C24208T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","C179235-","G182088A","G182189A","A196614-"],"OPG027":["E57K"],"OPG210":["E245K"]},"labels":{"aa":"OPG027: E57K; OPG210: E245K"}}},{"name":"NODE_0000183","node_attrs":{"div":563,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G28483A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP451001","node_attrs":{"div":563,"accession":"OP451001","author":{"author":"Gigante,C.M.,Acheampong,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,McDermott,D.,Li,Y.","value":"Gigante,C.M.,Acheampong,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,McDermott,D.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV_USA_2022_NJ0002"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP451001/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A173314-","T173315-","A173316-","T173317-","-196615A"]}}},{"name":"OQ427129","node_attrs":{"div":567,"accession":"OQ427129","author":{"author":"Gigante,C.,Murray,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Atkinson,A.,Li,Y.","value":"Gigante,C.,Murray,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Atkinson,A.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV_USA_2022_UT0007"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ427129/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C15582T","C48299T","C122936T","G170349A","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG143":["R127Q"]},"labels":{"aa":"OPG143: R127Q"}}},{"name":"OQ918701","node_attrs":{"div":567,"accession":"OQ918701","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00490/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-10"},"strain_display":{"value":"USA/OQ918701/2023-02-10"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C21910T","G39552A","A57421-","C57422-","A57423-","A57424-","A57425-","A57426-","A57427-","G57428-","G57429-","A57430-","C57431-","A57432-","T57433-","G57434-","T57435-","A57436-","A57437-","A57438-","C57439-","T57440-","T57441-","G132490A","C150443T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T"],"OPG037":["R175K"],"OPG057":["S215F"],"OPG075":["K20-","F21-","T22-","C23-","P24-","F25-","C26-"],"OPG176":["T212I"]},"labels":{"aa":"OPG037: R175K; OPG057: S215F; OPG075: K20-, F21-, T22-, C23-, P24-, F25-, C26-; OPG176: T212I"}}}]}]},{"name":"NODE_0000184","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C24231T","C179226-","C179235-"]}},"children":[{"name":"OP390179","node_attrs":{"div":562,"accession":"OP390179","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"country":{"value":"Colombia"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"BOL-UNIMOL-MPX-293015-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-24"},"strain_display":{"value":"Colombia/OP390179/2022-08-24"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP382485","node_attrs":{"div":563,"accession":"OP382485","author":{"author":"Colson,P.","value":"Colson,P."},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"hMPXV-IHU00008"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"strain_display":{"value":"France/OP382485/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G184227A"],"OPG210":["D958N"]},"labels":{"aa":"OPG210: D958N"}}},{"name":"OR095033","node_attrs":{"div":563,"accession":"OR095033","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV/UZ_REGA_215/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-08"},"strain_display":{"value":"Belgium/OR095033/2022-08-08"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G61102A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG080":["S306F"]},"labels":{"aa":"OPG080: S306F"}}},{"name":"NODE_0000185","node_attrs":{"div":563,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G23457A"],"OPG039":["S221F"]},"labels":{"aa":"OPG039: S221F"}},"children":[{"name":"OP415236","node_attrs":{"div":563,"accession":"OP415236","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPX_ilzdZn_9000269"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415236/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A190409-","A190410-","T190411-","G190412-","G190413-","A190414-","T190415-","T190416-","C190417-","G190418-","C190419-","G190420-","T190421-","A190422-","T190423-","A190424-","G190425-","C190426-"]}}},{"name":"OR264365","node_attrs":{"div":563,"accession":"OR264365","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"12_A"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-18"},"strain_display":{"value":"Australia/OR264365/2022-07-18"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{}}}]}]}]}]}]}]},{"name":"NODE_0000186","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C70780T"]},"labels":{"clade":"B.1.5"}},"children":[{"name":"OP150925","node_attrs":{"div":557,"accession":"OP150925","author":{"author":"Gigante,C.,Xia,D.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y.","value":"Gigante,C.,Xia,D.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV_USA_2022_GA001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/OP150925/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON918656","node_attrs":{"div":561,"accession":"ON918656","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"country":{"value":"Taiwan"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/human/Taiwan/110-231642/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Taiwan/ON918656/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["C28702T","T34793C","T50861C","C51777T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG054":["T402A"],"OPG070":["V91A"],"OPG071":["E888K"]},"labels":{"aa":"OPG054: T402A; OPG070: V91A; OPG071: E888K"}}},{"name":"ON843165","node_attrs":{"div":557,"accession":"ON843165","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"Monkeypox/PT0033/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-24"},"strain_display":{"value":"Portugal/ON843165/2022-05-24"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON780017","node_attrs":{"div":557,"accession":"ON780017","author":{"author":"Gramigna,G.,Giombini,E.,Gruber,C.E.M.,Rueca,M.,Carletti,F.,Cicalini,S.,Lapa,D.,Puro,V.,Marani,A.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Rivano Capparuccia,M.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F.","value":"Gramigna,G.,Giombini,E.,Gruber,C.E.M.,Rueca,M.,Carletti,F.,Cicalini,S.,Lapa,D.,Puro,V.,Marani,A.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Rivano Capparuccia,M.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F."},"country":{"value":"Italy"},"institution":{"value":"INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"INMI-Pt4"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-21"},"strain_display":{"value":"Italy/ON780017/2022-05-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A"]}}},{"name":"OP450990","node_attrs":{"div":560,"accession":"OP450990","author":{"author":"Gigante,C.M.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y.","value":"Gigante,C.M.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV_USA_2022_NV0001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP450990/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G75554A","G147179A","G159373A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG185":["E153K"]},"labels":{"aa":"OPG185: E153K"}}},{"name":"OP414288","node_attrs":{"div":557,"accession":"OP414288","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"Monkeypox/PT0244/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-21"},"strain_display":{"value":"Portugal/OP414288/2022-06-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"]}}},{"name":"OP536756","node_attrs":{"div":559,"accession":"OP536756","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"9000376"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP536756/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C69888T","C150392T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG089":["S8L"],"OPG176":["S195F"]},"labels":{"aa":"OPG089: S8L; OPG176: S195F"}}},{"name":"OP555650","node_attrs":{"div":559,"accession":"OP555650","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"Monkeypox/PT0579/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-10"},"strain_display":{"value":"Portugal/OP555650/2022-09-10"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C41022T","A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159001A"],"OPG060":["R54K"],"OPG153":["D385-"],"OPG185":["D29N"]},"labels":{"aa":"OPG060: R54K; OPG153: D385-; OPG185: D29N"}}},{"name":"OP555598","node_attrs":{"div":565,"accession":"OP555598","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"Monkeypox/PT0527/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-19"},"strain_display":{"value":"Portugal/OP555598/2022-08-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G5876A","C87141T","C126707T","C128030T","C128417T","C133867T","C134247T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C187128T","C191334T"],"OPG015":["S94F"],"OPG015_dup":["S94F"],"OPG148":["S241L"]},"labels":{"aa":"OPG015: S94F; OPG015_dup: S94F; OPG148: S241L"}}},{"name":"OP783902","node_attrs":{"div":557,"accession":"OP783902","author":{"author":"Laubscher,F.,Marques-Melancia,S.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Marques-Melancia,S.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A."},"country":{"value":"Switzerland"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"hMPXV-CH-38347314/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-08"},"strain_display":{"value":"Switzerland/OP783902/2022-06-08"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ274883","node_attrs":{"div":557,"accession":"OQ274883","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/ON/RKI664"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ274883/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OR264397","node_attrs":{"div":561,"accession":"OR264397","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"34_A"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-16"},"strain_display":{"value":"Australia/OR264397/2022-08-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["T606-","C30283T","C37054T","-179197T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","G179589A","G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N"}}},{"name":"ON959175","node_attrs":{"div":557,"accession":"ON959175","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/RKI162"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/ON959175/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP524008","node_attrs":{"div":557,"accession":"OP524008","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/RKI406"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP524008/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000188","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C84063T","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}},"children":[{"name":"OQ547764","node_attrs":{"div":559,"accession":"OQ547764","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/ON/RKI737"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OQ547764/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150563-","G150565-","A150566-","T150567-","C190607T"]}}},{"name":"OQ773477","node_attrs":{"div":558,"accession":"OQ773477","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/ON/RKI858"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773477/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000189","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C160426T"]}},"children":[{"name":"OQ503755","node_attrs":{"div":563,"accession":"OQ503755","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MpxV/human/USA/WA-UW-113327/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"USA/OQ503755/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T10449-","A10450-","G10451-","A10452-","T10453-","G75332A","T124690C","C135762T","C144211T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G185394A"],"OPG095":["R177K"],"OPG210":["E1347K"]},"labels":{"aa":"OPG095: R177K; OPG210: E1347K"}}},{"name":"NODE_0000190","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G111379A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G165326A"],"OPG130":["S175L"],"OPG190":["E69K"]},"labels":{"aa":"OPG130: S175L; OPG190: E69K"}},"children":[{"name":"OP879727","node_attrs":{"div":560,"accession":"OP879727","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"country":{"value":"USA"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"NJ-MPXV-006-rpt1"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP879727/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP650029","node_attrs":{"div":563,"accession":"OP650029","author":{"author":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T.","value":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T."},"country":{"value":"USA"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV22/human/USA-OK-81"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-26"},"strain_display":{"value":"USA/OP650029/2022-07-26"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G22207A","C82187T","C120671T","T136555-","G136558C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG037":["S76F"]},"labels":{"aa":"OPG037: S76F"}}},{"name":"OQ721933","node_attrs":{"div":561,"accession":"OQ721933","author":{"author":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y.","value":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV_USA_2022_OH0005"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721933/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G48045A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","G173318-","G173319-","G173320-","C173321-","A173322-","A173323-","A173324-","A173325-","C173326-","A173327-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"]}}}]}]},{"name":"NODE_0000191","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C44333T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG064":["M522I"]},"labels":{"aa":"OPG064: M522I"}},"children":[{"name":"OP415189","node_attrs":{"div":558,"accession":"OP415189","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPX_luLfgA_9000208"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415189/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OR035675","node_attrs":{"div":559,"accession":"OR035675","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/UZ_REGA_69"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-30"},"strain_display":{"value":"Belgium/OR035675/2022-06-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G161488A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OR035702","node_attrs":{"div":562,"accession":"OR035702","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/UZ_REGA_96"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Belgium/OR035702/2022-05-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C29315T","C60396T","G149807A","C161572T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG046":["D139N"]},"labels":{"aa":"OPG046: D139N"}}},{"name":"OR449644","node_attrs":{"div":562,"accession":"OR449644","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/ON/RKI930"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449644/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G24983A","G46956A","G135180A","G143432A","G150551-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG066":["P158L"],"OPG164":["D219N"],"OPG193":["F263-"]},"labels":{"aa":"OPG066: P158L; OPG164: D219N; OPG193: F263-"}}},{"name":"NODE_0000192","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G93512T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG113":["K594N"]},"labels":{"aa":"OPG113: K594N"}},"children":[{"name":"OP358276","node_attrs":{"div":562,"accession":"OP358276","author":{"author":"Tramuto,F.","value":"Tramuto,F."},"country":{"value":"Italy"},"institution":{"value":"University of Palermo, Department of Health Promotion Sciences Maternal and Infant Care, Internal Medicine and Medical Specialties \"G. D'Alessandro\"\"\""},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"SIC-AOUP-UNIPA_VL_9aug"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-09"},"strain_display":{"value":"Italy/OP358276/2022-08-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C33103T","C114490T","C133295T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-"],"OPG049":["E17K"],"OPG133":["D403N"]},"labels":{"aa":"OPG049: E17K; OPG133: D403N"}}},{"name":"OR264417","node_attrs":{"div":560,"accession":"OR264417","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"43_A"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-22"},"strain_display":{"value":"Australia/OR264417/2022-06-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["G2898A","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","C194312T"]}}}]}]}]},{"name":"NODE_0000193","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N","clade":"B.1.2"}},"children":[{"name":"OP150927","node_attrs":{"div":557,"accession":"OP150927","author":{"author":"Gigante,C.,Pavlick,J.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y.","value":"Gigante,C.,Pavlick,J.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_USA_2022_WA001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/OP150927/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON929079","node_attrs":{"div":557,"accession":"ON929079","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/RKI124"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/ON929079/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-"]}}},{"name":"OP205082","node_attrs":{"div":558,"accession":"OP205082","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_UK_2022_9000079"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-15"},"strain_display":{"value":"United Kingdom/OP205082/2022-06-15"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C123899T","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG144":["D12N"]},"labels":{"aa":"OPG144: D12N"}}},{"name":"OP415193","node_attrs":{"div":557,"accession":"OP415193","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPX_gOirGi_9000215"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415193/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ274892","node_attrs":{"div":557,"accession":"OQ274892","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/ON/RKI673"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ274892/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-","C179172-"]}}},{"name":"OQ054238","node_attrs":{"div":560,"accession":"OQ054238","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_USA_2022_TX0016"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ054238/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C15575T","G16220A","G48662C","T173270-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A"],"OPG027":["S53L"],"OPG068":["M154I"]},"labels":{"aa":"OPG027: S53L; OPG068: M154I"}}},{"name":"NODE_0000194","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C20992T","G143789A"],"OPG036":["D25N"],"OPG165":["D92N"]},"labels":{"aa":"OPG036: D25N; OPG165: D92N"}},"children":[{"name":"NODE_0000195","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C29229T","C57492T","G73939A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG045":["D12N"],"OPG075":["E3K"],"OPG094":["D54N"]},"labels":{"aa":"OPG045: D12N; OPG075: E3K; OPG094: D54N"}},"children":[{"name":"OP536807","node_attrs":{"div":565,"accession":"OP536807","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"9000438"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536807/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G10475A","G23462A","C171808T","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG199":["S274L"]},"labels":{"aa":"OPG199: S274L"}}},{"name":"OP555557","node_attrs":{"div":562,"accession":"OP555557","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"Monkeypox/PT0478/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-08"},"strain_display":{"value":"Portugal/OP555557/2022-08-08"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C179172-"]}}}]},{"name":"NODE_0000196","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C147168T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG171":["L61F"]},"labels":{"aa":"OPG171: L61F"}},"children":[{"name":"OP279039","node_attrs":{"div":560,"accession":"OP279039","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/CAN/UN-NML-4117/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-28"},"strain_display":{"value":"Canada/OP279039/2022-06-28"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264413","node_attrs":{"div":560,"accession":"OR264413","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"42_B"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-22"},"strain_display":{"value":"Australia/OR264413/2022-06-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"]}}},{"name":"OR463713","node_attrs":{"div":561,"accession":"OR463713","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/ON/RKI759"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OR463713/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G66015A","G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","A181253-"],"OPG084":["D432N"]},"labels":{"aa":"OPG084: D432N"}}}]}]},{"name":"NODE_0000197","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188391T"]}},"children":[{"name":"OP215262","node_attrs":{"div":559,"accession":"OP215262","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/RKI238"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP215262/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G182303A"]}}},{"name":"OP205083","node_attrs":{"div":558,"accession":"OP205083","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_UK_2022_9000092"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-25"},"strain_display":{"value":"United Kingdom/OP205083/2022-05-25"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OP450991","node_attrs":{"div":559,"accession":"OP450991","author":{"author":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y.","value":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_USA_2022_TX0018"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP450991/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","G45781A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","-196615A"],"OPG064":["H40Y"]},"labels":{"aa":"OPG064: H40Y"}}},{"name":"OP536791","node_attrs":{"div":563,"accession":"OP536791","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"9000417"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP536791/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","G23288A","C36267T","G40863A","C85322T","G92048A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"],"OPG055":["D273N"],"OPG060":["S107L"]},"labels":{"aa":"OPG055: D273N; OPG060: S107L"}}},{"name":"OP615326","node_attrs":{"div":561,"accession":"OP615326","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/ON/RKI446"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP615326/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C101983T","C141757T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C160426T","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG121":["S65L"]},"labels":{"aa":"OPG121: S65L"}}},{"name":"OP605583","node_attrs":{"div":563,"accession":"OP605583","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"Slovenia-MPXV-42-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Slovenia/OP605583/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A161-","-607T","C17614A","C27187T","G111484A","G147305A","C159401A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG030":["V74L"],"OPG043":["D257N"],"OPG130":["T140I"],"OPG185":["S162Y"]},"labels":{"aa":"OPG030: V74L; OPG043: D257N; OPG130: T140I; OPG185: S162Y"}}},{"name":"OQ320468","node_attrs":{"div":559,"accession":"OQ320468","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_USA_2022_TN0014"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ320468/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","C150028T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A"],"OPG176":["R74C"]},"labels":{"aa":"OPG176: R74C"}}},{"name":"OR086973","node_attrs":{"div":559,"accession":"OR086973","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/UZ_REGA_164/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR086973/2022-07-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G135633A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"NODE_0000198","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T157527C","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}},"children":[{"name":"ON853649","node_attrs":{"div":563,"accession":"ON853649","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/RKI068"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/ON853649/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G22425A","G22971A","C26694A","C77829T"],"OPG042":["W135L"]},"labels":{"aa":"OPG042: W135L"}}},{"name":"OP555483","node_attrs":{"div":560,"accession":"OP555483","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"Monkeypox/PT0387/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-12"},"strain_display":{"value":"Portugal/OP555483/2022-07-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G154098A"]}}}]},{"name":"NODE_0000199","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T26669C","G96073A","G115235A","C125294T"],"OPG117":["D9N"]},"labels":{"aa":"OPG117: D9N"}},"children":[{"name":"OQ159027","node_attrs":{"div":564,"accession":"OQ159027","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/RKI632"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"Germany/OQ159027/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G77052A","C135868T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP959060","node_attrs":{"div":562,"accession":"OP959060","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"country":{"value":"Colombia"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"BOL-UNIMOL-MPX-293428-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-29"},"strain_display":{"value":"Colombia/OP959060/2022-10-29"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000200","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G8638A","C21548T","C188236T","C188339T"],"OPG037":["D296N"]},"labels":{"aa":"OPG037: D296N"}},"children":[{"name":"OQ503753","node_attrs":{"div":562,"accession":"OQ503753","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/USA/WA-UW-110466/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"USA/OQ503753/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-196615A"]}}},{"name":"NODE_0000201","node_attrs":{"div":564,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C47820T","C68218T"],"OPG085":["R105Q"]},"labels":{"aa":"OPG085: R105Q"}},"children":[{"name":"OQ503756","node_attrs":{"div":566,"accession":"OQ503756","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/USA/WA-UW-126801/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OQ503756/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","G12239A","G12488A","-196615A"],"OPG023":["S138L","S221F"]},"labels":{"aa":"OPG023: S138L, S221F"}}},{"name":"OR427343","node_attrs":{"div":565,"accession":"OR427343","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/USA/WA-UW-038917/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-XX"},"strain_display":{"value":"USA/OR427343/2023-03-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G100939A"]}}},{"name":"OR427340","node_attrs":{"div":564,"accession":"OR427340","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/USA/WA-UW-028603/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-XX"},"strain_display":{"value":"USA/OR427340/2023-02-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"OR427336","node_attrs":{"div":565,"accession":"OR427336","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/USA/WA-UW-019613/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-XX"},"strain_display":{"value":"USA/OR427336/2023-01-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","C165586T","-196615A"]}}},{"name":"OR499953","node_attrs":{"div":565,"accession":"OR499953","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00496/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-04-26"},"strain_display":{"value":"USA/OR499953/2023-04-26"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C102741T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG122":["S105L"]},"labels":{"aa":"OPG122: S105L"}}}]}]}]}]},{"name":"NODE_0000202","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G74360A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C"],"OPG094":["R194H"]},"labels":{"aa":"OPG094: R194H","clade":"B.1.1"}},"children":[{"name":"ON792321","node_attrs":{"div":557,"accession":"ON792321","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"country":{"value":"Switzerland"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba6450e/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-02"},"strain_display":{"value":"Switzerland/ON792321/2022-06-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","A19360-","T19361-","C19362-","A19363-","T19364-","T19365-","A43653-","T43654-","T43655-","A49176-","A49177-","T49178-","T49179-","T49180-","T49181-","A49182-","T49183-","T49184-","A49185-","A49186-","C49187-","G49188-","G49189-","T49190-","A49191-","A49192-","T49193-","A79063-","A79064-","T79065-","T79066-","T79067-","T79068-","A79069-","A79070-","T79071-","A79072-","T79073-","A79074-","A79075-","T79076-","A79077-","C79078-","T79079-","T79080-","A79081-","A79082-","A79083-","A79084-","A79085-","T79086-","G79087-","G79088-","A79089-","T79090-","G79091-","T79092-","T79093-","G79094-","T79095-","G79096-","T79097-","C79098-","G79099-","T79100-","T79101-","A79102-","A152691-","A152692-","T152693-","G152694-","A152695-","C152696-","G152697-","T152698-","A175944-","T175945-","A175946-","T175947-","C175948-","A175949-","A175950-","C179127A","C179136T","T179138A","T179148-","T179157-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","C179190T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T180493-","A180494-","T180495-","C180496-","A180497-","T180498-","T180499-"],"OPG063":["D50-"],"OPG068":["N329-","G330-","N331-","T332-","F333-","I334-"],"OPG205":["I97-","S98-","I99-"]},"labels":{"aa":"OPG063: D50-; OPG068: N329-, G330-, N331-, T332-, F333-, I334-; OPG205: I97-, S98-, I99-"}}},{"name":"ON694329","node_attrs":{"div":557,"accession":"ON694329","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/RKI025"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/ON694329/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-","A192490-","A192491-","G192492-","T192493-","T192494-","A192495-","G192496-","T192497-","T192498-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP339846","node_attrs":{"div":559,"accession":"OP339846","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/RKI289"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP339846/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168264T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","G187135A"],"OPG195":["S12F"]},"labels":{"aa":"OPG195: S12F"}}},{"name":"OP204857","node_attrs":{"div":559,"accession":"OP204857","author":{"author":"Rhie,G.-E.","value":"Rhie,G.-E."},"country":{"value":"South Korea"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV-ROK-P1-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"South Korea/OP204857/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["C786T","C71728T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G173429A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG091":["A120V"]},"labels":{"aa":"OPG091: A120V"}}},{"name":"OP382488","node_attrs":{"div":558,"accession":"OP382488","author":{"author":"Colson,P.","value":"Colson,P."},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMPXV-IHU00011"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-19"},"strain_display":{"value":"France/OP382488/2022-07-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C153387T","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP837475","node_attrs":{"div":559,"accession":"OP837475","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"DC_INS_MPX_1009_L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-19"},"strain_display":{"value":"Colombia/OP837475/2022-09-19"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C17764T","G54336A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG030":["D24N"],"OPG071":["P35S"]},"labels":{"aa":"OPG030: D24N; OPG071: P35S"}}},{"name":"OP752114","node_attrs":{"div":557,"accession":"OP752114","author":{"author":"Gigante,C.M.,Cogswell,K.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Morrison,S.S.,Desch,M.,Knipe,K.,Weigand,M.R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Grenz,L.,Li,Y.","value":"Gigante,C.M.,Cogswell,K.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Morrison,S.S.,Desch,M.,Knipe,K.,Weigand,M.R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Grenz,L.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV_USA_2022_OR0003"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP752114/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OQ547755","node_attrs":{"div":557,"accession":"OQ547755","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI728"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ547755/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150563-","T150564-","G150565-","A150566-","T150567-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179190-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","G181052-"],"OPG209":["G179-"]},"labels":{"aa":"OPG209: G179-"}}},{"name":"OR449656","node_attrs":{"div":557,"accession":"OR449656","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI942"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449656/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"OR427334","node_attrs":{"div":565,"accession":"OR427334","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MpxV/human/USA/WA-UW-121247/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR427334/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","C11810T","G52232A","G59218A","C63120T","G75522A","C119838T","C159899T","G160110A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG023":["R364K"],"OPG071":["S736L"],"OPG079":["S135L"]},"labels":{"aa":"OPG023: R364K; OPG071: S736L; OPG079: S135L"}}},{"name":"OR264400","node_attrs":{"div":559,"accession":"OR264400","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"36_B"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-15"},"strain_display":{"value":"Australia/OR264400/2022-08-15"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["T76084-","T76085-","G118500A","G160406A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG136":["T363M"]},"labels":{"aa":"OPG136: T363M"}}},{"name":"OR264368","node_attrs":{"div":558,"accession":"OR264368","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"15_B"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-22"},"strain_display":{"value":"Australia/OR264368/2022-08-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","T76084-","T76085-","T80846-","T80847-","T121121-","T133094-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","G183484A"],"OPG044":["K147-"],"OPG210":["R710K"]},"labels":{"aa":"OPG044: K147-; OPG210: R710K"}}},{"name":"OR095036","node_attrs":{"div":560,"accession":"OR095036","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/UZ_REGA_218/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-08"},"strain_display":{"value":"Belgium/OR095036/2022-08-08"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C25828T","G107496A","G109463A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG042":["E424K"]},"labels":{"aa":"OPG042: E424K"}}},{"name":"OR500078","node_attrs":{"div":557,"accession":"OR500078","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"country":{"value":"Romania"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Romania/B-8/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-29"},"strain_display":{"value":"Romania/OR500078/2022-06-29"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T92388-","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["F220-"]},"labels":{"aa":"OPG113: F220-"}}},{"name":"OR463727","node_attrs":{"div":559,"accession":"OR463727","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI784"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OR463727/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C14799T","G69951A","G150551-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","A181253-"],"OPG025":["D157N"],"OPG089":["G29E"]},"labels":{"aa":"OPG025: D157N; OPG089: G29E"}}},{"name":"NODE_0000203","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C17048T","G93828A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177009A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"],"OPG029":["D8N"],"OPG113":["E700K"],"OPG205":["E452K"]},"labels":{"aa":"OPG029: D8N; OPG113: E700K; OPG205: E452K"}},"children":[{"name":"OQ159028","node_attrs":{"div":561,"accession":"OQ159028","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/RKI633"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"Germany/OQ159028/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C41131T"],"OPG060":["E18K"]},"labels":{"aa":"OPG060: E18K"}}},{"name":"OQ735077","node_attrs":{"div":567,"accession":"OQ735077","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/PT0626/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-21"},"strain_display":{"value":"Portugal/OQ735077/2023-03-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-609T","A615-","C616-","C10929T","C22179T","G39515A","G77076A","G129659A","C129949T","G139167A","C196638-","T196639-"],"OPG023":["E658K"],"OPG151":["E246K"]},"labels":{"aa":"OPG023: E658K; OPG151: E246K"}}}]},{"name":"NODE_0000204","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C29887T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}},"children":[{"name":"OR264437","node_attrs":{"div":558,"accession":"OR264437","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"56_C"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-06"},"strain_display":{"value":"Australia/OR264437/2022-09-06"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-"],"OPG044":["K147-"]},"labels":{"aa":"OPG044: K147-"}}},{"name":"OR264424","node_attrs":{"div":558,"accession":"OR264424","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"47_A"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-13"},"strain_display":{"value":"Australia/OR264424/2022-07-13"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000205","node_attrs":{"div":564,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C42674T","C46672T","C56805T","C72314T","C103216T","C127628T","T152686-","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C180857T"],"OPG063":["E339K"],"OPG066":["E253K"],"OPG074":["M107I"],"OPG092":["D212N"],"OPG123":["V619I"],"OPG149":["P145S"]},"labels":{"aa":"OPG063: E339K; OPG066: E253K; OPG074: M107I; OPG092: D212N; OPG123: V619I; OPG149: P145S"}},"children":[{"name":"OR500085","node_attrs":{"div":564,"accession":"OR500085","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"country":{"value":"Romania"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Romania/B-35_R2/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-26"},"strain_display":{"value":"Romania/OR500085/2023-01-26"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179199C","-179200A","-179201T"]}}},{"name":"OR500086","node_attrs":{"div":566,"accession":"OR500086","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"country":{"value":"Romania"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Romania/B-35_R3/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-15"},"strain_display":{"value":"Romania/OR500086/2023-02-15"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G169748A","C179190T","T179192A","T179193A","A179198G","A185438C","C185439A"]}}}]},{"name":"NODE_0000206","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C11401T","T133102-","A136552-","T136553-","C136554-","C179190-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}},"children":[{"name":"OQ427112","node_attrs":{"div":560,"accession":"OQ427112","author":{"author":"Gigante,C.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y.","value":"Gigante,C.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV_USA_2022_NV0005"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ427112/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C72269T","G140194A","G158318A"],"OPG092":["D227N"],"OPG159":["D143N"],"OPG160":["S294L"]},"labels":{"aa":"OPG092: D227N; OPG159: D143N; OPG160: S294L"}}},{"name":"OQ721942","node_attrs":{"div":560,"accession":"OQ721942","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV_USA_2022_TX0051"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721942/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G23673A","G50121A","-133102T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"],"OPG039":["S149L"],"OPG069":["E46K"]},"labels":{"aa":"OPG039: S149L; OPG069: E46K"}}},{"name":"OR464214","node_attrs":{"div":558,"accession":"OR464214","author":{"author":"Gigante,C.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y.","value":"Gigante,C.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV_USA_2022_CA0008"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OR464214/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-"]}}}]},{"name":"NODE_0000207","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155698A"]}},"children":[{"name":"OR759194","node_attrs":{"div":567,"accession":"OR759194","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Canada/ON-PHOL106/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-01"},"strain_display":{"value":"Canada/OR759194/2022-07-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C7235T","C32798T","C55589T","C61706T","G115768A","T120124-","T120125-","A120126-","G120127-","A120128-","T120129-","A120130-","A120131-","T120132-","G127806A","G159118A","G162726A","C177833T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"],"OPG074":["E513K"],"OPG080":["V105I"],"OPG134":["D7N"],"OPG137":["L175-","D176-","N177-"],"OPG150":["E10K"],"OPG185":["D68N"]},"labels":{"aa":"OPG074: E513K; OPG080: V105I; OPG134: D7N; OPG137: L175-, D176-, N177-; OPG150: E10K; OPG185: D68N"}}},{"name":"NODE_0000208","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G161575A"]}},"children":[{"name":"OP245330","node_attrs":{"div":559,"accession":"OP245330","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPX/PT0076/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-23"},"strain_display":{"value":"Portugal/OP245330/2022-07-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"]}}},{"name":"OR459775","node_attrs":{"div":561,"accession":"OR459775","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"country":{"value":"South Korea"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV-ROK-P002-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-02"},"strain_display":{"value":"South Korea/OR459775/2022-09-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["G14640A","C108843T","G136558C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG025":["H210Y"],"OPG153":["I370M"]},"labels":{"aa":"OPG025: H210Y; OPG153: I370M"}}},{"name":"OR086942","node_attrs":{"div":559,"accession":"OR086942","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/UZ_REGA_133/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"strain_display":{"value":"Belgium/OR086942/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T133102-","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196748-","T196749-","C196750-"]}}}]}]},{"name":"NODE_0000209","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C22739T","C179190-"],"OPG038":["E141K"]},"labels":{"aa":"OPG038: E141K"}},"children":[{"name":"OP019276","node_attrs":{"div":558,"accession":"OP019276","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"country":{"value":"Austria"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMPXV/Austria/MUW1527495/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-21"},"strain_display":{"value":"Austria/OP019276/2022-06-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON808413","node_attrs":{"div":558,"accession":"ON808413","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"country":{"value":"United Kingdom"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"CVR_MPXV1a"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-15"},"strain_display":{"value":"United Kingdom/ON808413/2022-05-15"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP415188","node_attrs":{"div":559,"accession":"OP415188","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPX_dDDHx_9000207"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"United Kingdom/OP415188/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T33222-","A33223-","T33224-","T33225-","C33226-","T33227-","C33228-","A33229-","T33230-","T33231-","G33232-","C33233-","T33234-","T33235-","C144199T","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG050":["S59-","N60-","E61-","N62-","I63-"]},"labels":{"aa":"OPG050: S59-, N60-, E61-, N62-, I63-"}}},{"name":"OP523996","node_attrs":{"div":558,"accession":"OP523996","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/RKI397"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP523996/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-"]}}},{"name":"OP752118","node_attrs":{"div":561,"accession":"OP752118","author":{"author":"Gigante,C.M.,Epie,N.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Morrison,S.S.,Desch,M.,Knipe,K.,Weigand,M.R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Perez,T.,Li,Y.","value":"Gigante,C.M.,Epie,N.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Morrison,S.S.,Desch,M.,Knipe,K.,Weigand,M.R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Perez,T.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV_USA_2022_SC0005"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OP752118/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T4775-","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","G70775A","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C186124T","C189996T","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"],"OPG089":["D304N"],"OPG210":["S1590F"]},"labels":{"aa":"OPG089: D304N; OPG210: S1590F"}}},{"name":"NODE_0000210","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C22740T","C38937T"],"OPG056":["R33Q"]},"labels":{"aa":"OPG056: R33Q"}},"children":[{"name":"OP415276","node_attrs":{"div":561,"accession":"OP415276","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPX_KV9qz9_9000349"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415276/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C67659T","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG085":["M291I"]},"labels":{"aa":"OPG085: M291I"}}},{"name":"NODE_0000211","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G74362A","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","T136555-","A136556-","T136557-","G136558-","A136559-","T136560-","A136561-","T136562-","C136563-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C177240T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-"],"OPG094":["A195T"],"OPG153":["I370-","I371-","D372-","D373-","D374-","D375-","D376-","D377-"],"OPG205":["Q529*"]},"labels":{"aa":"OPG094: A195T; OPG153: I370-, I371-, D372-, D373-, D374-, D375-, D376-, D377-; OPG205: Q529*"}},"children":[{"name":"OP555641","node_attrs":{"div":562,"accession":"OP555641","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"Monkeypox/PT0570/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-02"},"strain_display":{"value":"Portugal/OP555641/2022-09-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OP555627","node_attrs":{"div":563,"accession":"OP555627","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"Monkeypox/PT0556/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-30"},"strain_display":{"value":"Portugal/OP555627/2022-08-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","G157775A","-196615A"]}}}]}]}]}]},{"name":"NODE_0000212","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C25644T"]},"labels":{"clade":"B.1.7"}},"children":[{"name":"ON843170","node_attrs":{"div":557,"accession":"ON843170","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"Monkeypox/PT0031/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-26"},"strain_display":{"value":"Portugal/ON843170/2022-05-26"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP205081","node_attrs":{"div":557,"accession":"OP205081","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_UK_2022_9000078"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-14"},"strain_display":{"value":"United Kingdom/OP205081/2022-06-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP413716","node_attrs":{"div":559,"accession":"OP413716","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"9000351"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP413716/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C31006T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C182707T"],"OPG210":["S451F"]},"labels":{"aa":"OPG210: S451F"}}},{"name":"OP615340","node_attrs":{"div":561,"accession":"OP615340","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/ON/RKI458"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP615340/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G23359A","C40251T","C114955T","C116175T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG039":["L254F"],"OPG058":["D62N"],"OPG133":["D248N"]},"labels":{"aa":"OPG039: L254F; OPG058: D62N; OPG133: D248N"}}},{"name":"OP597782","node_attrs":{"div":560,"accession":"OP597782","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"country":{"value":"USA"},"institution":{"value":"Minnesota Department of Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MN-MDH-MPXV_0008"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"strain_display":{"value":"USA/OP597782/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G74619A","G83118A","T87356C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG105":["A665T"],"OPG109":["K698E"]},"labels":{"aa":"OPG105: A665T; OPG109: K698E"}}},{"name":"OQ320507","node_attrs":{"div":560,"accession":"OQ320507","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_USA_2022_TN0013"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ320507/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","C1735T","C31714T","T149447C","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G195475A","-196615A"],"OPG048":["G151S"]},"labels":{"aa":"OPG048: G151S"}}},{"name":"OQ547747","node_attrs":{"div":557,"accession":"OQ547747","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/ON/RKI720"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ547747/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G150551-","G150568-","A150569-","T150570-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OR759218","node_attrs":{"div":559,"accession":"OR759218","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"hMpxV/Canada/ON-PHOL130/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759218/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C81095T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C172410T"]}}},{"name":"NODE_0000213","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G63147A"]}},"children":[{"name":"ON927248","node_attrs":{"div":562,"accession":"ON927248","author":{"author":"Chan,W.Y.,Mtshali,P.S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J.","value":"Chan,W.Y.,Mtshali,P.S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J."},"country":{"value":"South Africa"},"institution":{"value":"National Institute for Communicable Disease, Sequencing core facility"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"NICD-SVPL232"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-24"},"strain_display":{"value":"South Africa/ON927248/2022-06-24"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G10224A","G129761A","T143625A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C177847T","A196601C","-196615A"],"OPG021":["R213Q"],"OPG151":["D280N"],"OPG165":["I37N"],"OPG205":["S731L"]},"labels":{"aa":"OPG021: R213Q; OPG151: D280N; OPG165: I37N; OPG205: S731L"}}},{"name":"OR264426","node_attrs":{"div":558,"accession":"OR264426","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"48_C"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Australia/OR264426/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}}]},{"name":"NODE_0000214","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G120241A","-179194A","-179195T","T179244-","T179247-","T179248-","A179249-","T179250-","T179251-","T179253-","T179254-","T179255-","T179258-","T179260-","A179261-","T179262-","A179266-","T179267-","A181253-"],"OPG137":["D214N"]},"labels":{"aa":"OPG137: D214N"}},"children":[{"name":"ON911481","node_attrs":{"div":561,"accession":"ON911481","author":{"author":"Galan-Huerta,K.A.,Paz-Infanzon,M.,Ruiz-Higareda,A.F.,Nuzzolo-Shihadeh,L.,Camacho-Ortiz,A.,Bocanegra-Ibarias,P.,Rivas-Estilla,A.M.,Zacarias-Villarreal,D.,Yamallel-Ortega,L.A.,Guerrero-Putz,M.D.,Ocampo-Candiani,J.","value":"Galan-Huerta,K.A.,Paz-Infanzon,M.,Ruiz-Higareda,A.F.,Nuzzolo-Shihadeh,L.,Camacho-Ortiz,A.,Bocanegra-Ibarias,P.,Rivas-Estilla,A.M.,Zacarias-Villarreal,D.,Yamallel-Ortega,L.A.,Guerrero-Putz,M.D.,Ocampo-Candiani,J."},"country":{"value":"Mexico"},"institution":{"value":"Universidad Autonoma de Nuevo Leon - Facultad de Medicina, Centro de Investigacion e Innovacion en Virologia Medica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"Monkeypox/MX-UANL001/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-28"},"strain_display":{"value":"Mexico/ON911481/2022-06-28"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","G57088A","C127530T","T133098-","T133099-","T133100-","T133101-","T133102-","T168120C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-179244T","-179247T","-179248T","-179249A","-179250T","-179251T","-179253T","-179254T","-179255T","-179258T","-179260T","-179261A","-179262T","-179266A","-179267T","-181253A","-196615A","-196616A","-196617A"],"OPG074":["S13L"],"OPG149":["S112L"],"OPG193":["F263L"]},"labels":{"aa":"OPG074: S13L; OPG149: S112L; OPG193: F263L"}}},{"name":"OR463720","node_attrs":{"div":558,"accession":"OR463720","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/ON/RKI779"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OR463720/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179245-","G179246-","G179252-","G179256-","G179257-","C179259-","G179263-","C179264-","C179265-"]}}}]},{"name":"NODE_0000215","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C66249T","C88644A","C104134T","C112638T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG109":["K268N"],"OPG123":["A313T"]},"labels":{"aa":"OPG109: K268N; OPG123: A313T"}},"children":[{"name":"OP263628","node_attrs":{"div":561,"accession":"OP263628","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/RKI274"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP263628/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OP536778","node_attrs":{"div":563,"accession":"OP536778","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"9000400"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536778/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","G69081A","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G186489A","A196614-"],"OPG153":["D385-"],"OPG210":["D1712N"]},"labels":{"aa":"OPG153: D385-; OPG210: D1712N"}}}]},{"name":"NODE_0000216","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C14077T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP205084","node_attrs":{"div":560,"accession":"OP205084","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_UK_2022_9000093"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-30"},"strain_display":{"value":"United Kingdom/OP205084/2022-05-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C4529T","G155585A","G192681A"],"OPG003":["D27N"],"OPG003_dup":["D27N"]},"labels":{"aa":"OPG003: D27N; OPG003_dup: D27N"}}},{"name":"NODE_0000217","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G105860A"]}},"children":[{"name":"OP415197","node_attrs":{"div":561,"accession":"OP415197","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPX_2v76E1_9000221"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415197/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G41557A","G91376A"],"OPG061":["P110S"],"OPG112":["D44N"]},"labels":{"aa":"OPG061: P110S; OPG112: D44N"}}},{"name":"OR095063","node_attrs":{"div":559,"accession":"OR095063","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/UZ_REGA_245/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-16"},"strain_display":{"value":"Belgium/OR095063/2022-08-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}}]}]},{"name":"NODE_0000218","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C148771T"],"OPG174":["D209N"]},"labels":{"aa":"OPG174: D209N"}},"children":[{"name":"OR449631","node_attrs":{"div":560,"accession":"OR449631","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/ON/RKI917"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449631/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G69840A","C99542T","G150551-","A150563-","T150564-","G150565-","A150566-","T150567-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG118":["S366F"],"OPG193":["F263-"]},"labels":{"aa":"OPG118: S366F; OPG193: F263-"}}},{"name":"OR464198","node_attrs":{"div":559,"accession":"OR464198","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_USA_2022_NY0050"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OR464198/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C31881T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A"],"OPG048":["G95E"]},"labels":{"aa":"OPG048: G95E"}}},{"name":"NODE_0000219","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G114316A","G152437A"],"OPG133":["H461Y"]},"labels":{"aa":"OPG133: H461Y"}},"children":[{"name":"OQ159026","node_attrs":{"div":561,"accession":"OQ159026","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/RKI631"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"Germany/OQ159026/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G150547A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G187677A"]}}},{"name":"OQ627928","node_attrs":{"div":560,"accession":"OQ627928","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"country":{"value":"Italy"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"INMI-19442022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-14"},"strain_display":{"value":"Italy/OQ627928/2022-09-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-608T","G610-","T611-","A612-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}}]}]},{"name":"NODE_0000220","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G42504A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}},"children":[{"name":"OP324545","node_attrs":{"div":562,"accession":"OP324545","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"Monkeypox/PT0237/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-22"},"strain_display":{"value":"Portugal/OP324545/2022-06-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C5292T","G74267A","C115870T","A161784T","G191918A"],"OPG015":["D289N"],"OPG015_dup":["D289N"],"OPG094":["R163Q"]},"labels":{"aa":"OPG015: D289N; OPG015_dup: D289N; OPG094: R163Q"}}},{"name":"OP245307","node_attrs":{"div":560,"accession":"OP245307","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPX/PT0050/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Portugal/OP245307/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A796-","C797-","C134850T","C159741T","C196739-","T196740-"]}}},{"name":"OP204840","node_attrs":{"div":559,"accession":"OP204840","author":{"author":"Seang,S.,Burrel,S.,Todesco,E.,Leducq,V.,Monsel,G.,Le Pluart,D.,Cordevant,C.,Pourcher,V.,Palich,R.,Charpentier,C.","value":"Seang,S.,Burrel,S.,Todesco,E.,Leducq,V.,Monsel,G.,Le Pluart,D.,Cordevant,C.,Pourcher,V.,Palich,R.,Charpentier,C."},"country":{"value":"France"},"institution":{"value":"APHP Pitie Salpetriere SU, Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"PatientMPXV"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-10"},"strain_display":{"value":"France/OP204840/2022-06-10"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G163250A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196612-","A196613-","A196614-"]}}},{"name":"OP415190","node_attrs":{"div":561,"accession":"OP415190","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPX_KJ3uDD_9000210"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"United Kingdom/OP415190/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C36834T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G168034A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C181209T","A181253-"],"OPG055":["E84K"],"OPG193":["R234K"]},"labels":{"aa":"OPG055: E84K; OPG193: R234K"}}},{"name":"OP555475","node_attrs":{"div":558,"accession":"OP555475","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"Monkeypox/PT0379/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-06"},"strain_display":{"value":"Portugal/OP555475/2022-07-06"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000221","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C57173T"]}},"children":[{"name":"OP727822","node_attrs":{"div":565,"accession":"OP727822","author":{"author":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K.","value":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K."},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"PrEV_case_2"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-02"},"strain_display":{"value":"Belgium/OP727822/2022-10-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T604-","T605-","T606-","C11401T","C33964T","C36267T","G110285A","T133102-","C144366T","A174924T","G180608A","A188351-","G195316A"],"OPG052":["R11Q"],"OPG055":["D273N"],"OPG209":["E31K"]},"labels":{"aa":"OPG052: R11Q; OPG055: D273N; OPG209: E31K"}}},{"name":"NODE_0000222","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C142797T"],"OPG164":["S7L"]},"labels":{"aa":"OPG164: S7L"}},"children":[{"name":"OP279036","node_attrs":{"div":559,"accession":"OP279036","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MpxV/human/CAN/UN-NML-4112/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-30"},"strain_display":{"value":"Canada/OP279036/2022-06-30"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP378695","node_attrs":{"div":559,"accession":"OP378695","author":{"author":"Gigante,C.M.,Hauser,J.R.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y.","value":"Gigante,C.M.,Hauser,J.R.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_USA_2022_DC0010"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP378695/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T4775-","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP920699","node_attrs":{"div":565,"accession":"OP920699","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00361/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-31"},"strain_display":{"value":"USA/OP920699/2022-10-31"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G105325A","C108658T","G111379A","C149889T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G165395A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G184244A"],"OPG124":["S215F"],"OPG130":["S175L"],"OPG190":["E92K"]},"labels":{"aa":"OPG124: S215F; OPG130: S175L; OPG190: E92K"}}},{"name":"OR264396","node_attrs":{"div":564,"accession":"OR264396","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"33_A"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-07"},"strain_display":{"value":"Australia/OR264396/2022-09-07"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["G14622A","A28529-","A28530-","T76084-","T76085-","G101241A","T133102-","C136244T","C156446T","G174708A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG025":["R216C"],"OPG044":["K147-"],"OPG153":["R475K"],"OPG204":["M59I"]},"labels":{"aa":"OPG025: R216C; OPG044: K147-; OPG153: R475K; OPG204: M59I"}}},{"name":"OR209323","node_attrs":{"div":560,"accession":"OR209323","author":{"author":"Li,C.M.","value":"Li,C.M."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_USA_2022_NC0003"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR209323/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","G62268A","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","A196614-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OR759230","node_attrs":{"div":559,"accession":"OR759230","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"hMpxV/Canada/ON-PHOL146/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-01"},"strain_display":{"value":"Canada/OR759230/2022-07-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR759178","node_attrs":{"div":563,"accession":"OR759178","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"hMpxV/Canada/ON-PHOL090/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759178/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","G26352A","C30137T","C55072T","G130068A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"],"OPG042":["A249V"],"OPG047":["R353K"],"OPG073":["D24N"],"OPG151":["R382Q"]},"labels":{"aa":"OPG042: A249V; OPG047: R353K; OPG073: D24N; OPG151: R382Q"}}},{"name":"NODE_0000223","node_attrs":{"div":563,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C55036T","C96914T","G158254A","C170381T","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179176A","-179177T","-179178A","-179179T","-179180A"],"OPG073":["E36K"],"OPG117":["S289L"],"OPG198":["S115L"]},"labels":{"aa":"OPG073: E36K; OPG117: S289L; OPG198: S115L"}},"children":[{"name":"OQ918697","node_attrs":{"div":567,"accession":"OQ918697","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00486/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-18"},"strain_display":{"value":"USA/OQ918697/2023-02-18"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G73789A","C136435T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C166803T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","G178559A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG094":["G4R"],"OPG192":["P25S"]},"labels":{"aa":"OPG094: G4R; OPG192: P25S"}}},{"name":"OR464216","node_attrs":{"div":563,"accession":"OR464216","author":{"author":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y.","value":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_USA_2022_KS0007"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"USA/OR464216/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T"]}}}]}]}]}]},{"name":"NODE_0000224","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G190660A"],"OPG016":["R84K"]},"labels":{"aa":"OPG016: R84K","clade":"B.1.3"}},"children":[{"name":"ON983168","node_attrs":{"div":557,"accession":"ON983168","author":{"author":"Chmel,M.,Pajer,P.,Nagy,A.,Zlamal,M.,Jirincova,H.,Dresler,J.,Bartos,O.","value":"Chmel,M.,Pajer,P.,Nagy,A.,Zlamal,M.,Jirincova,H.,Dresler,J.,Bartos,O."},"country":{"value":"Czech Republic"},"institution":{"value":"Military Heatlh Institute, Military Heatlh Institute in Prague"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPxV/Prague_001/2022/flye_medaka"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-04-28"},"strain_display":{"value":"Czech Republic/ON983168/2022-04-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T80849-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OP314959","node_attrs":{"div":558,"accession":"OP314959","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"country":{"value":"USA"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV22/human/USA-NE-111"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-03"},"strain_display":{"value":"USA/OP314959/2022-08-03"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C119884T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A","-196616A","-196617A"],"OPG137":["P95S"]},"labels":{"aa":"OPG137: P95S"}}},{"name":"OP536804","node_attrs":{"div":558,"accession":"OP536804","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"9000432"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536804/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","C6423A","C135775T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","T190787-","A196614-"]}}},{"name":"OR449633","node_attrs":{"div":557,"accession":"OR449633","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/ON/RKI919"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449633/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"NODE_0000225","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C39898T","C148933T","G171318A","C175241T"],"OPG057":["D100N"],"OPG174":["E155K"],"OPG199":["E111K"],"OPG204":["S237L"]},"labels":{"aa":"OPG057: D100N; OPG174: E155K; OPG199: E111K; OPG204: S237L"}},"children":[{"name":"OP205121","node_attrs":{"div":561,"accession":"OP205121","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_UK_2022_9000164"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"strain_display":{"value":"United Kingdom/OP205121/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OP415237","node_attrs":{"div":567,"accession":"OP415237","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPX_oJ2Z6R_9000271"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415237/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C5023T","C17196T","C80447T","C127215T","G150190A","C164347T","G192187A"],"OPG149":["S7L"],"OPG176":["D128N"],"OPG189":["R339C"]},"labels":{"aa":"OPG149: S7L; OPG176: D128N; OPG189: R339C"}}}]},{"name":"NODE_0000226","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C64426T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}},"children":[{"name":"OQ721953","node_attrs":{"div":565,"accession":"OQ721953","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"country":{"value":"Taiwan"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/human/Taiwan/110-525030/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-XX"},"strain_display":{"value":"Taiwan/OQ721953/2023-03-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C166940T","T177665A","A177666T","A177667T","G178104T","G178290T","T178629A","G196412A"],"OPG205":["N670K","N671F"]},"labels":{"aa":"OPG205: N670K, N671F"}}},{"name":"NODE_0000227","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G55133A"],"OPG074":["R665C"]},"labels":{"aa":"OPG074: R665C"}},"children":[{"name":"ON792320","node_attrs":{"div":560,"accession":"ON792320","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"country":{"value":"Switzerland"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba6449f/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-01"},"strain_display":{"value":"Switzerland/ON792320/2022-06-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G159376A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG185":["D154N"]},"labels":{"aa":"OPG185: D154N"}}},{"name":"ON782054","node_attrs":{"div":561,"accession":"ON782054","author":{"author":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"country":{"value":"Spain"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0001a/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-31"},"strain_display":{"value":"Spain/ON782054/2022-05-31"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G50337A","A122238T","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A169759G","A193392G","T193688C","T194099C","T194619C","T195948C","-196615A"],"OPG001_dup":["L105S"],"OPG002_dup":["F54S"],"OPG003_dup":["N264D"],"OPG069":["G118R"],"OPG143":["S360T"]},"labels":{"aa":"OPG001_dup: L105S; OPG002_dup: F54S; OPG003_dup: N264D; OPG069: G118R; OPG143: S360T"}}},{"name":"ON754987","node_attrs":{"div":560,"accession":"ON754987","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_SI2022_S1_VEROE6"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-23"},"strain_display":{"value":"Slovenia/ON754987/2022-05-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A33-","T157-","-607T","G167517A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG193":["E62K"]},"labels":{"aa":"OPG193: E62K"}}},{"name":"ON622722","node_attrs":{"div":560,"accession":"ON622722","country":{"value":"France"},"institution":{"value":"Virology, GENomique EPIdemiologique das maladies Infectieuses, France"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_FR_HCL0001_2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-22"},"strain_display":{"value":"France/ON622722/2022-05-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C109627A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG129":["A460S"]},"labels":{"aa":"OPG129: A460S"}}},{"name":"OP215273","node_attrs":{"div":561,"accession":"OP215273","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/RKI251"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP215273/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G5515A","T54004C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179259T","C191695T"]}}},{"name":"OP205133","node_attrs":{"div":560,"accession":"OP205133","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_UK_2022_9000188"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-29"},"strain_display":{"value":"United Kingdom/OP205133/2022-06-29"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","C142545T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG163":["S115F"]},"labels":{"aa":"OPG163: S115F"}}},{"name":"OP205067","node_attrs":{"div":559,"accession":"OP205067","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_UK_2022_9000061"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-27"},"strain_display":{"value":"United Kingdom/OP205067/2022-05-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OP523994","node_attrs":{"div":562,"accession":"OP523994","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/RKI392"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP523994/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G36659A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G174642A","C190444T"],"OPG016":["S12L"],"OPG055":["A142V"],"OPG204":["M37I"]},"labels":{"aa":"OPG016: S12L; OPG055: A142V; OPG204: M37I"}}},{"name":"OP605585","node_attrs":{"div":563,"accession":"OP605585","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"Slovenia-MPXV-44-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Slovenia/OP605585/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","C8612T","G52232A","C56018T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G187156A"],"OPG071":["S736L"],"OPG074":["E370K"]},"labels":{"aa":"OPG071: S736L; OPG074: E370K"}}},{"name":"OP605552","node_attrs":{"div":559,"accession":"OP605552","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"Slovenia-MPXV-09-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Slovenia/OP605552/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T38-","T157-","-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP605562","node_attrs":{"div":565,"accession":"OP605562","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"Slovenia-MPXV-20-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Slovenia/OP605562/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","A29748T","G72609A","G72610T","G72611T","T72614A","A72617C","A72977-","A72978-","T72979-","G72980-","A72981-"],"OPG047":["*483K"],"OPG092":["C111G","K112*","P113N","T114S"]},"labels":{"aa":"OPG047: *483K; OPG092: C111G, K112*, P113N, T114S"}}},{"name":"OP555633","node_attrs":{"div":560,"accession":"OP555633","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"Monkeypox/PT0562/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Portugal/OP555633/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168066T"],"OPG153":["D385-"],"OPG193":["Q245*"]},"labels":{"aa":"OPG153: D385-; OPG193: Q245*"}}},{"name":"OP555564","node_attrs":{"div":559,"accession":"OP555564","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"Monkeypox/PT0488/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-11"},"strain_display":{"value":"Portugal/OP555564/2022-08-11"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP879736","node_attrs":{"div":559,"accession":"OP879736","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"country":{"value":"USA"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"NJ-MPXV-017-rep2"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-29"},"strain_display":{"value":"USA/OP879736/2022-06-29"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ274889","node_attrs":{"div":559,"accession":"OQ274889","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/ON/RKI670"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ274889/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OR035715","node_attrs":{"div":559,"accession":"OR035715","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/UZ_REGA_109"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035715/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"]}}},{"name":"OR035686","node_attrs":{"div":560,"accession":"OR035686","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/UZ_REGA_80"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-09"},"strain_display":{"value":"Belgium/OR035686/2022-08-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C22950T","T133101-","T133102-","C133161T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ773470","node_attrs":{"div":559,"accession":"OQ773470","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/ON/RKI851"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773470/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-"]}}},{"name":"OR264391","node_attrs":{"div":559,"accession":"OR264391","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"2_A"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-10"},"strain_display":{"value":"Australia/OR264391/2022-08-10"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["T80846-","T80847-","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OR134560","node_attrs":{"div":570,"accession":"OR134560","author":{"author":"Miller,H.,Bajwa,M.","value":"Miller,H.,Bajwa,M."},"country":{"value":"USA"},"institution":{"value":"Delaware Public Health Lab, Sequencing/Bioinformatics"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"B1221136"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-13"},"strain_display":{"value":"USA/OR134560/2023-03-13"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C19558T","G32277A","C35688T","G39140A","G55059A","G75512A","C110402T","C121161T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C170673T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179542T","C189174T"],"OPG034":["E150K"],"OPG049":["S292L"],"OPG073":["S28L"],"OPG095":["R237K"],"OPG139":["A70T"]},"labels":{"aa":"OPG034: E150K; OPG049: S292L; OPG073: S28L; OPG095: R237K; OPG139: A70T"}}},{"name":"OX248696","node_attrs":{"div":561,"accession":"OX248696","country":{"value":"Slovakia"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"RNA"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-04"},"strain_display":{"value":"Slovakia/OX248696/2022-07-04"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","G37250A","C138080T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG155":["E138K"]},"labels":{"aa":"OPG155: E138K"}}},{"name":"ON782021","node_attrs":{"div":559,"accession":"ON782021","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O."},"country":{"value":"Finland"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPX-37/Finland/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-24"},"strain_display":{"value":"Finland/ON782021/2022-05-24"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ557947","node_attrs":{"div":559,"accession":"OQ557947","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_USA_2022_NY0008"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OQ557947/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A"]}}},{"name":"NODE_0000228","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A140126-","C140127-","T168120C","-179234A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-"],"OPG159":["N120-"],"OPG193":["F263L"]},"labels":{"aa":"OPG159: N120-; OPG193: F263L"}},"children":[{"name":"OP144214","node_attrs":{"div":561,"accession":"OP144214","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P."},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/ITM_pt_25/Belgium/16-Jun-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-16"},"strain_display":{"value":"Belgium/OP144214/2022-06-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C133161T","C157632T"]}}},{"name":"ON950045","node_attrs":{"div":560,"accession":"ON950045","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,Van den Bossche,D.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Van Esbroeck,M.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,Van den Bossche,D.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Van Esbroeck,M."},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/ITM_pt_31/Belgium/27-May-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-27"},"strain_display":{"value":"Belgium/ON950045/2022-05-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T133102-","A140104-","A140105-","T140106-","A140107-","A140108-","C140109-","A140110-","A140111-","T140112-","T140113-","A140114-","T140115-","A140116-","A140117-","C140118-","A140119-","A140120-","T140121-","T140122-","A140123-","T140124-","A140125-","A140128-","A140129-","T140130-","T140131-","A140132-","T140133-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","A140143-","A140144-","T140145-","T140146-","G140147-","T140148-","T140149-","A140150-","T140151-","A140152-","A140153-","T140154-","A140155-","A140156-","T140157-","T140158-","A140159-","T140160-","A140161-","A140162-","T140163-","T140164-","G140165-","T140166-","T140167-","T179267-","-196615A"],"OPG159":["N113-","N114-","N115-","Y116-","N117-","N118-","Y119-","N121-","Y122-","N123-","N124-","Y125-","N126-","C127-","Y128-","N129-","N130-","Y131-","N132-","C133-","Y134-"]},"labels":{"aa":"OPG159: N113-, N114-, N115-, Y116-, N117-, N118-, Y119-, N121-, Y122-, N123-, N124-, Y125-, N126-, C127-, Y128-, N129-, N130-, Y131-, N132-, C133-, Y134-"}}}]},{"name":"NODE_0000230","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C133161T","C157632T"]}},"children":[{"name":"OP555472","node_attrs":{"div":561,"accession":"OP555472","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"Monkeypox/PT0376/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-07"},"strain_display":{"value":"Portugal/OP555472/2022-07-07"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159243A"]}}},{"name":"OR086974","node_attrs":{"div":561,"accession":"OR086974","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/UZ_REGA_165/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR086974/2022-07-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G41336A","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000231","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G152776A"],"OPG180":["D29N"]},"labels":{"aa":"OPG180: D29N"}},"children":[{"name":"OQ451903","node_attrs":{"div":571,"accession":"OQ451903","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2023/RKI718"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-XX"},"strain_display":{"value":"Germany/OQ451903/2023-01-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","C15969T","C17998T","G40610A","C43803T","C63879T","G70190A","G118289A","C147011T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C159532T","G161629A","C189427T"],"OPG005":["P77S"],"OPG027":["E137K"],"OPG031":["M277I"],"OPG064":["G699E"],"OPG083":["D280N"],"OPG089":["E109K"],"OPG185":["P206S"],"OPG188":["E12K"]},"labels":{"aa":"OPG005: P77S; OPG027: E137K; OPG031: M277I; OPG064: G699E; OPG083: D280N; OPG089: E109K; OPG185: P206S; OPG188: E12K"}}},{"name":"OQ581854","node_attrs":{"div":562,"accession":"OQ581854","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"country":{"value":"Taiwan"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/human/Taiwan/109-005210/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-XX"},"strain_display":{"value":"Taiwan/OQ581854/2023-02-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["T64426C","G158406A","A192404-","G192405-","T192406-","A192411-"]}}}]},{"name":"NODE_0000232","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G85581A"],"OPG107":["V24I"]},"labels":{"aa":"OPG107: V24I"}},"children":[{"name":"OQ320451","node_attrs":{"div":561,"accession":"OQ320451","author":{"author":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y.","value":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_USA_2022_DC0022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ320451/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C112740T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A"]}}},{"name":"OR759179","node_attrs":{"div":561,"accession":"OR759179","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"hMpxV/Canada/ON-PHOL091/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759179/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C122502T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG143":["D272N"]},"labels":{"aa":"OPG143: D272N"}}}]},{"name":"NODE_0000233","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G105923A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG124":["L16F"]},"labels":{"aa":"OPG124: L16F","clade":"C.1"}},"children":[{"name":"LC753968","node_attrs":{"div":560,"accession":"LC753968","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"country":{"value":"Japan"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220165"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Japan/LC753968/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{}}},{"name":"LC753969","node_attrs":{"div":560,"accession":"LC753969","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"country":{"value":"Japan"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220176"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"Japan/LC753969/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{}}},{"name":"OR035728","node_attrs":{"div":561,"accession":"OR035728","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/UZ_REGA_122"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035728/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G149818A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG176":["D4N"]},"labels":{"aa":"OPG176: D4N"}}},{"name":"OQ581853","node_attrs":{"div":562,"accession":"OQ581853","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"country":{"value":"Taiwan"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Taiwan/110-093831/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-XX"},"strain_display":{"value":"Taiwan/OQ581853/2023-02-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["T132513C","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C185069T"]}}},{"name":"NODE_0000234","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C166940T","G193223A"]}},"children":[{"name":"OQ721952","node_attrs":{"div":568,"accession":"OQ721952","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"country":{"value":"Taiwan"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Taiwan/240031000030/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-XX"},"strain_display":{"value":"Taiwan/OQ721952/2023-03-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["C798T","C13503T","G33539A","G34948A","G40174A","G156025A","A183935G","A184219G"],"OPG025":["A589T"],"OPG054":["A350V"],"OPG057":["P8S"],"OPG210":["I860M","Y955C"]},"labels":{"aa":"OPG025: A589T; OPG054: A350V; OPG057: P8S; OPG210: I860M, Y955C"}}},{"name":"NODE_0000235","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C3987T"]}},"children":[{"name":"LC756925","node_attrs":{"div":563,"accession":"LC756925","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"country":{"value":"Japan"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220342"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-09"},"strain_display":{"value":"Japan/LC756925/2023-02-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["C84734T"]}}},{"name":"LC756923","node_attrs":{"div":562,"accession":"LC756923","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"country":{"value":"Japan"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220318"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-25"},"strain_display":{"value":"Japan/LC756923/2023-01-25"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{}}},{"name":"OR427348","node_attrs":{"div":565,"accession":"OR427348","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MpxV/human/USA/WA-UW-066957/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-06-XX"},"strain_display":{"value":"USA/OR427348/2023-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G26855A","C30191T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C155490T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG047":["R335H"]},"labels":{"aa":"OPG047: R335H"}}},{"name":"OR665166","node_attrs":{"div":567,"accession":"OR665166","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MpxV/human/USA/WA-UW-092809/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-09-XX"},"strain_display":{"value":"USA/OR665166/2023-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","G13434A","G29650A","C33332T","G37974A","C74691T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG025":["R612C"],"OPG046":["T27I"],"OPG050":["R26Q"],"OPG056":["S354L"]},"labels":{"aa":"OPG025: R612C; OPG046: T27I; OPG050: R26Q; OPG056: S354L"}}},{"name":"OR499979","node_attrs":{"div":565,"accession":"OR499979","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00522/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-05-08"},"strain_display":{"value":"USA/OR499979/2023-05-08"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G11924A","C134237T","G178951A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG023":["S326L"]},"labels":{"aa":"OPG023: S326L"}}},{"name":"OR459802","node_attrs":{"div":563,"accession":"OR459802","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"country":{"value":"South Korea"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV-ROK-P032-2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-04-25"},"strain_display":{"value":"South Korea/OR459802/2023-04-25"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["C52108T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000236","node_attrs":{"div":564,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C149963T","G184562A"],"OPG176":["S52L"]},"labels":{"aa":"OPG176: S52L"}},"children":[{"name":"OR459778","node_attrs":{"div":565,"accession":"OR459778","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"country":{"value":"South Korea"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV-ROK-P005-2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-13"},"strain_display":{"value":"South Korea/OR459778/2023-03-13"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["G85691A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000237","node_attrs":{"div":567,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C21062T","G188348A","C188946T"],"OPG036":["M1I"]},"labels":{"aa":"OPG036: M1I"}},"children":[{"name":"OR643705","node_attrs":{"div":573,"accession":"OR643705","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00563/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-08-16"},"strain_display":{"value":"USA/OR643705/2023-08-16"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G21880A","G47532A","C125074T","G133704A","G133838A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T180483A"],"OPG037":["S185F"]},"labels":{"aa":"OPG037: S185F"}}},{"name":"NODE_0000238","node_attrs":{"div":569,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G101241A","G152866A"],"OPG180":["D59N"]},"labels":{"aa":"OPG180: D59N"}},"children":[{"name":"OR743500","node_attrs":{"div":572,"accession":"OR743500","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1031"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-10-XX"},"strain_display":{"value":"Germany/OR743500/2023-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T57476C","C142797T","G173397A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-"],"OPG075":["Q8R"],"OPG164":["S7L"]},"labels":{"aa":"OPG075: Q8R; OPG164: S7L"}}},{"name":"NODE_0000239","node_attrs":{"div":570,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G13563A"],"OPG025":["P569S"]},"labels":{"aa":"OPG025: P569S"}},"children":[{"name":"OR381843","node_attrs":{"div":570,"accession":"OR381843","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"Monkeypox/PT0649/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-07-10"},"strain_display":{"value":"Portugal/OR381843/2023-07-10"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000240","node_attrs":{"div":572,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T611-","C37738T","G151847A","C191053-","A191054-","T191055-","G191056-","G191057-","A191058-","G191059-","T191060-","C191061-","G191062-","G191063-","T191064-","A191065-","G191066-","A191067-","T191068-","T191069-","T191070-","C191071-","A191072-","T191073-","G191074-","G191075-","C191076-","T191077-","G191078-","T191079-","C191080-","G191081-","A191082-","T191083-","G191084-","A191085-","G191086-","C191087-","A191088-","G191089-","T191090-","T191091-","T191092-","C191093-","A191094-","C191095-","G191096-","A191097-","C191098-","G191099-","A191100-","C191101-","C191102-","T191103-","C191104-","G191105-","A191106-","T191107-","C191108-","T191109-","T191110-","T191111-","G191112-","G191113-","T191114-","C191115-","A191116-","T191117-","T191118-","A191119-","T191120-","C191121-","T191122-","T191123-","T191124-","G191125-","G191126-","T191127-","A191128-","G191129-"],"OPG056":["E433K"]},"labels":{"aa":"OPG056: E433K"}},"children":[{"name":"OR326997","node_attrs":{"div":572,"accession":"OR326997","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/PT0633/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-06-25"},"strain_display":{"value":"Portugal/OR326997/2023-06-25"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-608T","G610-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-"]}}},{"name":"OR519723","node_attrs":{"div":576,"accession":"OR519723","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-08-XX"},"strain_display":{"value":"Germany/OR519723/2023-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-611T","C56879T","C57492T","G121291A","G172945A"],"OPG074":["E83K"],"OPG075":["E3K"]},"labels":{"aa":"OPG074: E83K; OPG075: E3K"}}},{"name":"OR487988","node_attrs":{"div":572,"accession":"OR487988","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/PT0667/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-08-01"},"strain_display":{"value":"Portugal/OR487988/2023-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A784-","T785-","T196689-","C196690-"]}}}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}} diff --git a/data/nextstrain/mpox/clade-iib/CHANGELOG.md b/data/nextstrain/mpox/clade-iib/CHANGELOG.md new file mode 100644 index 00000000..1a0c18a8 --- /dev/null +++ b/data/nextstrain/mpox/clade-iib/CHANGELOG.md @@ -0,0 +1,13 @@ +## Unreleased + +Initial release of this dataset. This dataset is similar to the v2 dataset [`hMPXV/NC_063383.1`](https://github.com/nextstrain/nextclade_data/tree/2023-08-17--15-51-24--UTC/data/datasets/hMPXV/references/NC_063383.1/versions/2023-08-01T12%3A00%3A00Z/files) with some differences. + +### New and changed gene names + +Some genes have been renamed and one has been added. The new annotation is based on NCBI refseq annotations that were released in November 2022. The v2 dataset predates this refseq: + +- The 4 genes in the inverted terminal repeat segment (ITR) on both ends of the genome (OPG001, OPG002, OPG003,OPG015) are now all included. The genes on the 3' end (~positions 190000-197000) now have an `_dup` appended to distinguish them. +- The gene previously named `NBT03_gp052` is now called `OPG073` +- The gene previously named `NBT03_gp174` is now called `OPG016` +- The gene previously named `NBT03_gp175` is now called `OPG015_dup` +- Gene `OPG166` has been added diff --git a/data/nextstrain/mpox/clade-iib/README.md b/data/nextstrain/mpox/clade-iib/README.md new file mode 100644 index 00000000..ea947155 --- /dev/null +++ b/data/nextstrain/mpox/clade-iib/README.md @@ -0,0 +1,23 @@ +# Nextclade dataset for "Mpox virus (Clade IIb)" + +| Key | Value | +| ---------------------- | --------------------------------------------------------------------------------------------------------------------- | +| authors | [Cornelius Roemer](https://neherlab.org), [Richard Neher](https://neherlab.org), [Nextstrain](https://nextstrain.org) | +| data source | Genbank | +| workflow | [github.com/nextstrain/mpox/nextclade](https://github.com/nextstrain/mpox/nextclade) | +| nextclade dataset path | nextstrain/mpox/clade-iib | +| annotation | [NC_063383.1](https://www.ncbi.nlm.nih.gov/nuccore/NC_063383) | +| clade definitions | [github.com/mpxv-lineages/lineage-designation](https://github.com/mpxv-lineages/lineage-designation) | +| related datasets | Mpox virus (All clades): `nextstrain/mpox/all-clades`
Mpox virus (Lineage B.1) `nextstrain/mpox/lineage-b.1` | + +This dataset is for Mpox viruses of clade IIb. A more specific dataset just for outbreak lineage B.1 is available as `nextstrain/mpox/lineage-b.1`. There is also a broader dataset for all clades I, IIa and IIb under `nextstrain/mpox/all-clades`. + +The lineage system used is defined in [Happi et al. (2022)](https://doi.org/10.1371/journal.pbio.3001769). Lineage definitions are available at [github.com/mpxv-lineages/lineage-designation](https://github.com/nextstrain/mpox/nextclade). + +The reference used in this dataset is the clade IIb NCBI refseq `NC_063383.1` (Isolate `MPXV-M5312_HM12_Rivers`). + +The reference tree consists of around 5000 sequences with representatives from all clade IIb lineages. + +## Further reading + +Read more about Nextclade datasets in Nextclade documentation: https://docs.nextstrain.org/projects/nextclade/en/stable/user/datasets.html diff --git a/data/nextstrain/mpox/clade-iib/genome_annotation.gff3 b/data/nextstrain/mpox/clade-iib/genome_annotation.gff3 new file mode 100644 index 00000000..432d5465 --- /dev/null +++ b/data/nextstrain/mpox/clade-iib/genome_annotation.gff3 @@ -0,0 +1,391 @@ +##gff-version 3 +#!gff-spec-version 1.21 +#!processor NCBI annotwriter +##sequence-region NC_063383.1 1 197209 +##species https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10244 +NC_063383.1 RefSeq region 1 197209 . + . ID=NC_063383.1:1..197209;Dbxref=taxon:10244;collection-date=2018-08;country=Nigeria: Rivers State;gbkey=Src;genome=genomic;genotype=MPXV clade 2;isolate=MPXV-M5312_HM12_Rivers;mol_type=genomic DNA;nat-host=Homo sapiens +NC_063383.1 RefSeq long_terminal_repeat 1 6422 . - . ID=id-NC_063383.1:1..6422;gbkey=repeat_region;rpt_type=long_terminal_repeat +NC_063383.1 RefSeq gene 835 1575 . - . ID=gene-NBT03_gp001;Dbxref=GeneID:72551607;Name=OPG001;gbkey=Gene;gene=OPG001;gene_biotype=protein_coding;locus_tag=NBT03_gp001;old_locus_tag=MPXV-M5312_HM12_Rivers-001 +NC_063383.1 RefSeq CDS 835 1575 . - 0 ID=cds-YP_010377002.1;Parent=gene-NBT03_gp001;Dbxref=GenBank:YP_010377002.1,GeneID:72551607;Name=OPG001;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp001%3B Chemokine binding protein (Cop-C23L)%3B most abundant secreted protein%3B CC-chemokine binding%3B similar to VACV-WR J1L and VACV-Cop C23L;gbkey=CDS;gene=OPG001;locus_tag=NBT03_gp001;product=Chemokine binding protein;protein_id=YP_010377002.1 +NC_063383.1 RefSeq gene 1702 2751 . - . ID=gene-NBT03_gp002;Dbxref=GeneID:72551418;Name=OPG002;gbkey=Gene;gene=OPG002;gene_biotype=protein_coding;locus_tag=NBT03_gp002;old_locus_tag=MPXV-M5312_HM12_Rivers-002 +NC_063383.1 RefSeq CDS 1702 2751 . - 0 ID=cds-YP_010377003.1;Parent=gene-NBT03_gp002;Dbxref=GenBank:YP_010377003.1,GeneID:72551418;Name=OPG002;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: NBT03_gp002%3B TNF receptor (CrmB)%3B similar to VACV-WR J2L and VACV-Cop C22L;gbkey=CDS;gene=OPG002;locus_tag=NBT03_gp002;product=Crm-B secreted TNF-alpha-receptor-like protein;protein_id=YP_010377003.1 +NC_063383.1 RefSeq gene 2841 4607 . - . ID=gene-NBT03_gp003;Dbxref=GeneID:72551419;Name=OPG003;gbkey=Gene;gene=OPG003;gene_biotype=protein_coding;locus_tag=NBT03_gp003;old_locus_tag=MPXV-M5312_HM12_Rivers-003 +NC_063383.1 RefSeq CDS 2841 4607 . - 0 ID=cds-YP_010377004.1;Parent=gene-NBT03_gp003;Dbxref=GenBank:YP_010377004.1,GeneID:72551419;Name=OPG003;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp003%3B Ankyrin%3B similar to VACV-WR J3L and VACV-Cop C19L;gbkey=CDS;gene=OPG003;locus_tag=NBT03_gp003;product=Ankyrin repeat protein (25);protein_id=YP_010377004.1 +NC_063383.1 RefSeq gene 4843 6156 . - . ID=gene-NBT03_gp004;Dbxref=GeneID:72551420;Name=OPG015;gbkey=Gene;gene=OPG015;gene_biotype=protein_coding;locus_tag=NBT03_gp004;old_locus_tag=MPXV-M5312_HM12_Rivers-004 +NC_063383.1 RefSeq CDS 4843 6156 . - 0 ID=cds-YP_010377005.1;Parent=gene-NBT03_gp004;Dbxref=GenBank:YP_010377005.1,GeneID:72551420;Name=OPG015;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp004%3B Ankyrin%3B similar to VACV-WR D1L and CPXV-017;gbkey=CDS;gene=OPG015;locus_tag=NBT03_gp004;product=Ankyrin repeat protein (39);protein_id=YP_010377005.1 +NC_063383.1 RefSeq sequence_feature 6270 6419 . - . ID=id-NC_063383.1:6270..6419;exon_number=OPG016;gbkey=misc_feature;number=OPG016 +NC_063383.1 RefSeq sequence_feature 6444 6885 . - . ID=id-NC_063383.1:6444..6885;exon_number=OPG017;gbkey=misc_feature;number=OPG017 +NC_063383.1 RefSeq sequence_feature 6966 7463 . - . ID=id-NC_063383.1:6966..7463;exon_number=OPG018;gbkey=misc_feature;number=OPG018 +NC_063383.1 RefSeq gene 7580 8008 . + . ID=gene-NBT03_gp005;Dbxref=GeneID:72551421;Name=OPG019;gbkey=Gene;gene=OPG019;gene_biotype=protein_coding;locus_tag=NBT03_gp005;old_locus_tag=MPXV-M5312_HM12_Rivers-006 +NC_063383.1 RefSeq CDS 7580 8008 . + 0 ID=cds-YP_010377006.1;Parent=gene-NBT03_gp005;Dbxref=GenBank:YP_010377006.1,GeneID:72551421;Name=OPG019;Note=Taxonomic breadth: chordopoxvirinae%3B secreted growth factor Secreted EGF-like protein%3B similar to VACV-WR D3R and VACV-Cop C11R;gbkey=CDS;gene=OPG019;locus_tag=NBT03_gp005;product=EGF-like domain protein;protein_id=YP_010377006.1 +NC_063383.1 RefSeq sequence_feature 8136 9102 . - . ID=id-NC_063383.1:8136..9102;exon_number=OPG020;gbkey=misc_feature;number=OPG020 +NC_063383.1 RefSeq gene 9587 10315 . + . ID=gene-NBT03_gp006;Dbxref=GeneID:72551422;Name=OPG021;gbkey=Gene;gene=OPG021;gene_biotype=protein_coding;locus_tag=NBT03_gp006;old_locus_tag=MPXV-M5312_HM12_Rivers-008 +NC_063383.1 RefSeq CDS 9587 10315 . + 0 ID=cds-YP_010377007.1;Parent=gene-NBT03_gp006;Dbxref=GenBank:YP_010377007.1,GeneID:72551422;Name=OPG021;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp008%3B Zinc finger-like protein%3B zinc binding%3B virosome localization%3B virulence factor%3B inhibition of apoptosis induced by UV irradiation%3B similar to VACV-WR D5R;gbkey=CDS;gene=OPG021;locus_tag=NBT03_gp006;product=Zinc finger-like protein (2);protein_id=YP_010377007.1 +NC_063383.1 RefSeq gene 10478 10858 . - . ID=gene-NBT03_gp007;Dbxref=GeneID:72551423;Name=OPG022;gbkey=Gene;gene=OPG022;gene_biotype=protein_coding;locus_tag=NBT03_gp007;old_locus_tag=MPXV-M5312_HM12_Rivers-009 +NC_063383.1 RefSeq CDS 10478 10858 . - 0 ID=cds-YP_010377008.1;Parent=gene-NBT03_gp007;Dbxref=GenBank:YP_010377008.1,GeneID:72551423;Name=OPG022;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp009%3B secreted IL-18 binding protein%3B Soluble IL-18 binding protein (Bsh-D7L)%3B similar to VACV-WR D6L;gbkey=CDS;gene=OPG022;locus_tag=NBT03_gp007;product=Interleukin-18-binding protein;protein_id=YP_010377008.1 +NC_063383.1 RefSeq gene 10918 12900 . - . ID=gene-NBT03_gp008;Dbxref=GeneID:72551424;Name=OPG023;gbkey=Gene;gene=OPG023;gene_biotype=protein_coding;locus_tag=NBT03_gp008;old_locus_tag=MPXV-M5312_HM12_Rivers-010 +NC_063383.1 RefSeq CDS 10918 12900 . - 0 ID=cds-YP_010377009.1;Parent=gene-NBT03_gp008;Dbxref=GenBank:YP_010377009.1,GeneID:72551424;Name=OPG023;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp010%3B host range%3B ankyrin-like%3B Ankyrin/Host Range (Bang-D8L)%3B similar to VACV-WR D7L;gbkey=CDS;gene=OPG023;locus_tag=NBT03_gp008;product=Ankyrin repeat protein (2);protein_id=YP_010377009.1 +NC_063383.1 RefSeq gene 13034 13228 . - . ID=gene-NBT03_gp009;Dbxref=GeneID:72551425;Name=OPG024;gbkey=Gene;gene=OPG024;gene_biotype=protein_coding;locus_tag=NBT03_gp009;old_locus_tag=MPXV-M5312_HM12_Rivers-011 +NC_063383.1 RefSeq CDS 13034 13228 . - 0 ID=cds-YP_010377010.1;Parent=gene-NBT03_gp009;Dbxref=GenBank:YP_010377010.1,GeneID:72551425;Name=OPG024;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp011%3B ANK-containing protein%3B similar to VACV-WR D8L;gbkey=CDS;gene=OPG024;locus_tag=NBT03_gp009;product=retroviral pseudoprotease-like protein;protein_id=YP_010377010.1 +NC_063383.1 RefSeq gene 13375 15267 . - . ID=gene-NBT03_gp010;Dbxref=GeneID:72551426;Name=OPG025;gbkey=Gene;gene=OPG025;gene_biotype=protein_coding;locus_tag=NBT03_gp010;old_locus_tag=MPXV-M5312_HM12_Rivers-012 +NC_063383.1 RefSeq CDS 13375 15267 . - 0 ID=cds-YP_010377011.1;Parent=gene-NBT03_gp010;Dbxref=GenBank:YP_010377011.1,GeneID:72551426;Name=OPG025;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp012%3B ankyrin-like%3B Type I IFN resistance%3B similar to VACV-WR D9L and VACV-Cop C9L;gbkey=CDS;gene=OPG025;locus_tag=NBT03_gp010;product=Ankyrin repeat protein (14);protein_id=YP_010377011.1 +NC_063383.1 RefSeq sequence_feature 15310 15854 . - . ID=id-NC_063383.1:15310..15854;exon_number=OPG026;gbkey=misc_feature;number=OPG026 +NC_063383.1 RefSeq gene 15925 16377 . - . ID=gene-NBT03_gp011;Dbxref=GeneID:72551427;Name=OPG027;gbkey=Gene;gene=OPG027;gene_biotype=protein_coding;locus_tag=NBT03_gp011;old_locus_tag=MPXV-M5312_HM12_Rivers-013 +NC_063383.1 RefSeq CDS 15925 16377 . - 0 ID=cds-YP_010377012.1;Parent=gene-NBT03_gp011;Dbxref=GenBank:YP_010377012.1,GeneID:72551427;Name=OPG027;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp013%3B host range%3B Type 1 IFN inhibitor%3B similar to VACV-WR D10L and VACV-Cop C7L;gbkey=CDS;gene=OPG027;locus_tag=NBT03_gp011;product=Host range protein;protein_id=YP_010377012.1 +NC_063383.1 RefSeq gene 16602 17069 . - . ID=gene-NBT03_gp012;Dbxref=GeneID:72551428;Name=OPG029;gbkey=Gene;gene=OPG029;gene_biotype=protein_coding;locus_tag=NBT03_gp012;old_locus_tag=MPXV-M5312_HM12_Rivers-014 +NC_063383.1 RefSeq CDS 16602 17069 . - 0 ID=cds-YP_010377013.1;Parent=gene-NBT03_gp012;Dbxref=GenBank:YP_010377013.1,GeneID:72551428;Name=OPG029;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp014%3B Putative tlr signaling inhibitor%2C IFN-beta inhibitor%3B similar to VACV-WR D11L and VACV-Cop C6L;gbkey=CDS;gene=OPG029;locus_tag=NBT03_gp012;product=Bcl-2-like protein;protein_id=YP_010377013.1 +NC_063383.1 RefSeq gene 17213 17833 . - . ID=gene-NBT03_gp013;Dbxref=GeneID:72551429;Name=OPG030;gbkey=Gene;gene=OPG030;gene_biotype=protein_coding;locus_tag=NBT03_gp013;old_locus_tag=MPXV-M5312_HM12_Rivers-015 +NC_063383.1 RefSeq CDS 17213 17833 . - 0 ID=cds-YP_010377014.1;Parent=gene-NBT03_gp013;Dbxref=GenBank:YP_010377014.1,GeneID:72551429;Name=OPG030;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp015%3B BTB domain of kelch-like protein%3B Kelch-like protein%3B similar to VACV-WR D12L and VACV-Cop C5L;gbkey=CDS;gene=OPG030;locus_tag=NBT03_gp013;product=Kelch-like protein (1);protein_id=YP_010377014.1 +NC_063383.1 RefSeq gene 17878 18828 . - . ID=gene-NBT03_gp014;Dbxref=GeneID:72551430;Name=OPG031;gbkey=Gene;gene=OPG031;gene_biotype=protein_coding;locus_tag=NBT03_gp014;old_locus_tag=MPXV-M5312_HM12_Rivers-016 +NC_063383.1 RefSeq CDS 17878 18828 . - 0 ID=cds-YP_010377015.1;Parent=gene-NBT03_gp014;Dbxref=GenBank:YP_010377015.1,GeneID:72551430;Name=OPG031;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp016%3B IL-1 receptor antagonist%3B similar to VACV-WR D13L and VACV-Cop C10L;gbkey=CDS;gene=OPG031;locus_tag=NBT03_gp014;product=C4L/C10L-like family protein;protein_id=YP_010377015.1 +NC_063383.1 RefSeq sequence_feature 18902 19288 . - . ID=id-NC_063383.1:18902..19288;exon_number=OPG033;gbkey=misc_feature;number=OPG033 +NC_063383.1 RefSeq gene 19361 20005 . - . ID=gene-NBT03_gp015;Dbxref=GeneID:72551431;Name=OPG034;gbkey=Gene;gene=OPG034;gene_biotype=protein_coding;locus_tag=NBT03_gp015;old_locus_tag=MPXV-M5312_HM12_Rivers-018 +NC_063383.1 RefSeq CDS 19361 20005 . - 0 ID=cds-YP_010377017.1;Parent=gene-NBT03_gp015;Dbxref=GenBank:YP_010377017.1,GeneID:72551431;Name=OPG034;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp022%3B Putative TLR signalling inhibitor%3B start of ORF is missing approx. 18 AA compared to CPXVs%3B similar to VACV-WR D19L and VACV-Cop C1L;gbkey=CDS;gene=OPG034;locus_tag=NBT03_gp015;product=Bcl-2-like protein;protein_id=YP_010377017.1 +NC_063383.1 RefSeq gene 20051 20404 . - . ID=gene-NBT03_gp016;Dbxref=GeneID:72551432;Name=OPG035;gbkey=Gene;gene=OPG035;gene_biotype=protein_coding;locus_tag=NBT03_gp016;old_locus_tag=MPXV-M5312_HM12_Rivers-019 +NC_063383.1 RefSeq CDS 20051 20404 . - 0 ID=cds-YP_010377018.1;Parent=gene-NBT03_gp016;Dbxref=GenBank:YP_010377018.1,GeneID:72551432;Name=OPG035;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp023%3B secreted virulence factor%3B Putative tlr signaling inhibitor%3B Anti-apoptotic Bcl-2-like protein%3B similar to VACV-WR P1L and VACV-Cop N1L;gbkey=CDS;gene=OPG035;locus_tag=NBT03_gp016;product=Bcl-2-like protein;protein_id=YP_010377018.1 +NC_063383.1 RefSeq gene 20531 21064 . - . ID=gene-NBT03_gp017;Dbxref=GeneID:72551433;Name=OPG036;gbkey=Gene;gene=OPG036;gene_biotype=protein_coding;locus_tag=NBT03_gp017;old_locus_tag=MPXV-M5312_HM12_Rivers-020 +NC_063383.1 RefSeq CDS 20531 21064 . - 0 ID=cds-YP_010377019.1;Parent=gene-NBT03_gp017;Dbxref=GenBank:YP_010377019.1,GeneID:72551433;Name=OPG036;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp024%3B Alpha amanatin target protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR P2L and VACV-Cop #N2L;gbkey=CDS;gene=OPG036;locus_tag=NBT03_gp017;product=Bcl-2-like protein;protein_id=YP_010377019.1 +NC_063383.1 RefSeq gene 21105 22433 . - . ID=gene-NBT03_gp018;Dbxref=GeneID:72551434;Name=OPG037;gbkey=Gene;gene=OPG037;gene_biotype=protein_coding;locus_tag=NBT03_gp018;old_locus_tag=MPXV-M5312_HM12_Rivers-021 +NC_063383.1 RefSeq CDS 21105 22433 . - 0 ID=cds-YP_010377020.1;Parent=gene-NBT03_gp018;Dbxref=GenBank:YP_010377020.1,GeneID:72551434;Name=OPG037;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp025%3B ankyrin-like%3B ANK-containing protein%3B apoptosis inhibitor%3B start of ORF is missing approx. 31 AA compared to CPXVs%3B similar to VACV-WR O1L and VACV-Cop M1L;gbkey=CDS;gene=OPG037;locus_tag=NBT03_gp018;product=Ankyrin-like protein (1);protein_id=YP_010377020.1 +NC_063383.1 RefSeq gene 22497 23159 . - . ID=gene-NBT03_gp019;Dbxref=GeneID:72551435;Name=OPG038;gbkey=Gene;gene=OPG038;gene_biotype=protein_coding;locus_tag=NBT03_gp019;old_locus_tag=MPXV-M5312_HM12_Rivers-022 +NC_063383.1 RefSeq CDS 22497 23159 . - 0 ID=cds-YP_010377021.1;Parent=gene-NBT03_gp019;Dbxref=GenBank:YP_010377021.1,GeneID:72551435;Name=OPG038;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp026%3B NFkB inhibitor%3B similar to VACV-WR O2L and VACV-Cop M2L;gbkey=CDS;gene=OPG038;locus_tag=NBT03_gp019;product=NFkB inhibitor;protein_id=YP_010377021.1 +NC_063383.1 RefSeq gene 23264 24118 . - . ID=gene-NBT03_gp020;Dbxref=GeneID:72551436;Name=OPG039;gbkey=Gene;gene=OPG039;gene_biotype=protein_coding;locus_tag=NBT03_gp020;old_locus_tag=MPXV-M5312_HM12_Rivers-023 +NC_063383.1 RefSeq CDS 23264 24118 . - 0 ID=cds-YP_010377022.1;Parent=gene-NBT03_gp020;Dbxref=GenBank:YP_010377022.1,GeneID:72551436;Name=OPG039;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp027%3B host range%3B ankyrin-like%3B Ankyrin/NFkB inhibitor%3B similar to VACV-WR C1L and VACV-Cop K1L;gbkey=CDS;gene=OPG039;locus_tag=NBT03_gp020;product=Ankyrin-like protein (3);protein_id=YP_010377022.1 +NC_063383.1 RefSeq gene 24351 25478 . - . ID=gene-NBT03_gp021;Dbxref=GeneID:72551437;Name=OPG040;gbkey=Gene;gene=OPG040;gene_biotype=protein_coding;locus_tag=NBT03_gp021;old_locus_tag=MPXV-M5312_HM12_Rivers-024 +NC_063383.1 RefSeq CDS 24351 25478 . - 0 ID=cds-YP_010377023.1;Parent=gene-NBT03_gp021;Dbxref=GenBank:YP_010377023.1,GeneID:72551437;Name=OPG040;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp028%3B serine protease inhibitor-like%2C SPI-3%3B inhibition of the ability of infected cells to fuse%3B Serpin 1%2C2%2C3%3B similar to VACV-WR C2L and VACV-Cop K2L;gbkey=CDS;gene=OPG040;locus_tag=NBT03_gp021;product=Serpin;protein_id=YP_010377023.1 +NC_063383.1 RefSeq sequence_feature 25529 25767 . - . ID=id-NC_063383.1:25529..25767;exon_number=OPG041;gbkey=misc_feature;number=OPG041 +NC_063383.1 RefSeq gene 25823 27097 . - . ID=gene-NBT03_gp022;Dbxref=GeneID:72551438;Name=OPG042;gbkey=Gene;gene=OPG042;gene_biotype=protein_coding;locus_tag=NBT03_gp022;old_locus_tag=MPXV-M5312_HM12_Rivers-026 +NC_063383.1 RefSeq CDS 25823 27097 . - 0 ID=cds-YP_010377025.1;Parent=gene-NBT03_gp022;Dbxref=GenBank:YP_010377025.1,GeneID:72551438;Name=OPG042;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp030%3B phospholipase D-like%3B Phospholipase-D-like protein%3B similar to VACV-WR C4L and VACV-Cop K4L;gbkey=CDS;gene=OPG042;locus_tag=NBT03_gp022;product=Phospholipase-D-like protein;protein_id=YP_010377025.1 +NC_063383.1 RefSeq gene 27125 27955 . - . ID=gene-NBT03_gp023;Dbxref=GeneID:72551439;Name=OPG043;gbkey=Gene;gene=OPG043;gene_biotype=protein_coding;locus_tag=NBT03_gp023;old_locus_tag=MPXV-M5312_HM12_Rivers-027 +NC_063383.1 RefSeq CDS 27125 27955 . - 0 ID=cds-YP_010377026.1;Parent=gene-NBT03_gp023;Dbxref=GenBank:YP_010377026.1,GeneID:72551439;Name=OPG043;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp031%3B lysophospholipase-like%3B Monoglyceride lipase%3B similar to VACV-WR C5L and VACV-Cop K5L;gbkey=CDS;gene=OPG043;locus_tag=NBT03_gp023;product=Putative monoglyceride lipase;protein_id=YP_010377026.1 +NC_063383.1 RefSeq gene 28091 28540 . + . ID=gene-NBT03_gp024;Dbxref=GeneID:72551440;Name=OPG044;gbkey=Gene;gene=OPG044;gene_biotype=protein_coding;locus_tag=NBT03_gp024;old_locus_tag=MPXV-M5312_HM12_Rivers-028 +NC_063383.1 RefSeq CDS 28091 28540 . + 0 ID=cds-YP_010377027.1;Parent=gene-NBT03_gp024;Dbxref=GenBank:YP_010377027.1,GeneID:72551440;Name=OPG044;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp032%3B Putative tlr signaling inhibitor%3B Host immune response repressor%3B similar to VACV-WR C6R and VACV-Cop #K7R;gbkey=CDS;gene=OPG044;locus_tag=NBT03_gp024;product=Bcl-2-like protein;protein_id=YP_010377027.1 +NC_063383.1 RefSeq gene 28603 29262 . - . ID=gene-NBT03_gp025;Dbxref=GeneID:72551441;Name=OPG045;gbkey=Gene;gene=OPG045;gene_biotype=protein_coding;locus_tag=NBT03_gp025;old_locus_tag=MPXV-M5312_HM12_Rivers-029 +NC_063383.1 RefSeq CDS 28603 29262 . - 0 ID=cds-YP_010377028.1;Parent=gene-NBT03_gp025;Dbxref=GenBank:YP_010377028.1,GeneID:72551441;Name=OPG045;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp033%3B Caspase-9 (apoptosis) inhibitor (mitochondrial- associated)%3B similar to VACV-WR C7L and VACV-Cop F1L;gbkey=CDS;gene=OPG045;locus_tag=NBT03_gp025;product=Caspase-9 inhibitor;protein_id=YP_010377028.1 +NC_063383.1 RefSeq gene 29274 29729 . - . ID=gene-NBT03_gp026;Dbxref=GeneID:72551442;Name=OPG046;gbkey=Gene;gene=OPG046;gene_biotype=protein_coding;locus_tag=NBT03_gp026;old_locus_tag=MPXV-M5312_HM12_Rivers-030 +NC_063383.1 RefSeq CDS 29274 29729 . - 0 ID=cds-YP_010377029.1;Parent=gene-NBT03_gp026;Dbxref=GenBank:YP_010377029.1,GeneID:72551442;Name=OPG046;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp034%3B deoxyuridine triphosphatase%3B dUTPase%3B similar to VACV-WR C8L and VACV-Cop F2L;gbkey=CDS;gene=OPG046;locus_tag=NBT03_gp026;product=dUTPase;protein_id=YP_010377029.1 +NC_063383.1 RefSeq gene 29746 31194 . - . ID=gene-NBT03_gp027;Dbxref=GeneID:72551443;Name=OPG047;gbkey=Gene;gene=OPG047;gene_biotype=protein_coding;locus_tag=NBT03_gp027;old_locus_tag=MPXV-M5312_HM12_Rivers-031 +NC_063383.1 RefSeq CDS 29746 31194 . - 0 ID=cds-YP_010377030.1;Parent=gene-NBT03_gp027;Dbxref=GenBank:YP_010377030.1,GeneID:72551443;Name=OPG047;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp035%3B kelch-like%3B Kelch-like protein%3B similar to VACV-WR C9L and VACV-Cop F3L;gbkey=CDS;gene=OPG047;locus_tag=NBT03_gp027;product=Kelch-like protein (2);protein_id=YP_010377030.1 +NC_063383.1 RefSeq gene 31205 32164 . - . ID=gene-NBT03_gp028;Dbxref=GeneID:72551444;Name=OPG048;gbkey=Gene;gene=OPG048;gene_biotype=protein_coding;locus_tag=NBT03_gp028;old_locus_tag=MPXV-M5312_HM12_Rivers-032 +NC_063383.1 RefSeq CDS 31205 32164 . - 0 ID=cds-YP_010377031.1;Parent=gene-NBT03_gp028;Dbxref=GenBank:YP_010377031.1,GeneID:72551444;Name=OPG048;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp036%3B Ribonucleotide reductase small subunit%2C R2%3B similar to VACV-WR C10L and VACV-Cop F4L;gbkey=CDS;gene=OPG048;locus_tag=NBT03_gp028;product=Ribonucleotide reductase small subunit;protein_id=YP_010377031.1 +NC_063383.1 RefSeq gene 32195 33151 . - . ID=gene-NBT03_gp029;Dbxref=GeneID:72551445;Name=OPG049;gbkey=Gene;gene=OPG049;gene_biotype=protein_coding;locus_tag=NBT03_gp029;old_locus_tag=MPXV-M5312_HM12_Rivers-033 +NC_063383.1 RefSeq CDS 32195 33151 . - 0 ID=cds-YP_010377032.1;Parent=gene-NBT03_gp029;Dbxref=GenBank:YP_010377032.1,GeneID:72551445;Name=OPG049;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp037%3B 36kDa major membrane protein%3B similar to VACV-WR C11L and VACV-Cop F5L;gbkey=CDS;gene=OPG049;locus_tag=NBT03_gp029;product=Telomere-binding protein I6 (1);protein_id=YP_010377032.1 +NC_063383.1 RefSeq gene 33181 33408 . - . ID=gene-NBT03_gp030;Dbxref=GeneID:72551446;Name=OPG050;gbkey=Gene;gene=OPG050;gene_biotype=protein_coding;locus_tag=NBT03_gp030;old_locus_tag=MPXV-M5312_HM12_Rivers-034 +NC_063383.1 RefSeq CDS 33181 33408 . - 0 ID=cds-YP_010377033.1;Parent=gene-NBT03_gp030;Dbxref=GenBank:YP_010377033.1,GeneID:72551446;Name=OPG050;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp038%3B Hypothetical protein%3B similar to VACV-WR C12L and VACV-Cop F6L;gbkey=CDS;gene=OPG050;locus_tag=NBT03_gp030;product=CPXV053 protein;protein_id=YP_010377033.1 +NC_063383.1 RefSeq gene 33425 33649 . - . ID=gene-NBT03_gp031;Dbxref=GeneID:72551447;Name=OPG051;gbkey=Gene;gene=OPG051;gene_biotype=protein_coding;locus_tag=NBT03_gp031;old_locus_tag=MPXV-M5312_HM12_Rivers-035 +NC_063383.1 RefSeq CDS 33425 33649 . - 0 ID=cds-YP_010377034.1;Parent=gene-NBT03_gp031;Dbxref=GenBank:YP_010377034.1,GeneID:72551447;Name=OPG051;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp039%3B Hypothetical protein%3B similar to VACV-WR C13L and VACV-Cop F7L;gbkey=CDS;gene=OPG051;locus_tag=NBT03_gp031;product=CPXV054 protein;protein_id=YP_010377034.1 +NC_063383.1 RefSeq gene 33801 33995 . - . ID=gene-NBT03_gp032;Dbxref=GeneID:72551448;Name=OPG052;gbkey=Gene;gene=OPG052;gene_biotype=protein_coding;locus_tag=NBT03_gp032;old_locus_tag=MPXV-M5312_HM12_Rivers-036 +NC_063383.1 RefSeq CDS 33801 33995 . - 0 ID=cds-YP_010377035.1;Parent=gene-NBT03_gp032;Dbxref=GenBank:YP_010377035.1,GeneID:72551448;Name=OPG052;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp040%3B Cytoplasmic protein%3B similar to VACV-WR C14L and VACV-Cop F8L;gbkey=CDS;gene=OPG052;locus_tag=NBT03_gp032;product=Cytoplasmic protein;protein_id=YP_010377035.1 +NC_063383.1 RefSeq gene 34052 34690 . - . ID=gene-NBT03_gp033;Dbxref=GeneID:72551449;Name=OPG053;gbkey=Gene;gene=OPG053;gene_biotype=protein_coding;locus_tag=NBT03_gp033;old_locus_tag=MPXV-M5312_HM12_Rivers-037 +NC_063383.1 RefSeq CDS 34052 34690 . - 0 ID=cds-YP_010377036.1;Parent=gene-NBT03_gp033;Dbxref=GenBank:YP_010377036.1,GeneID:72551449;Name=OPG053;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp041%3B S-S bond formation pathway protein substrate%3B similar to VACV-WR C15L and VACV-Cop F9L;gbkey=CDS;gene=OPG053;locus_tag=NBT03_gp033;product=IMV membrane protein L1R;protein_id=YP_010377036.1 +NC_063383.1 RefSeq gene 34677 35996 . - . ID=gene-NBT03_gp034;Dbxref=GeneID:72551450;Name=OPG054;gbkey=Gene;gene=OPG054;gene_biotype=protein_coding;locus_tag=NBT03_gp034;old_locus_tag=MPXV-M5312_HM12_Rivers-038 +NC_063383.1 RefSeq CDS 34677 35996 . - 0 ID=cds-YP_010377037.1;Parent=gene-NBT03_gp034;Dbxref=GenBank:YP_010377037.1,GeneID:72551450;Name=OPG054;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp042%3B serine%3B Essential Ser/Thr kinase morph%3B similar to VACV-WR C16L and VACV-Cop F10L;gbkey=CDS;gene=OPG054;locus_tag=NBT03_gp034;product=Serine/threonine-protein kinase;protein_id=YP_010377037.1 +NC_063383.1 RefSeq gene 36019 37083 . - . ID=gene-NBT03_gp035;Dbxref=GeneID:72551451;Name=OPG055;gbkey=Gene;gene=OPG055;gene_biotype=protein_coding;locus_tag=NBT03_gp035;old_locus_tag=MPXV-M5312_HM12_Rivers-039 +NC_063383.1 RefSeq CDS 36019 37083 . - 0 ID=cds-YP_010377038.1;Parent=gene-NBT03_gp035;Dbxref=GenBank:YP_010377038.1,GeneID:72551451;Name=OPG055;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp043%3B RhoA signalling inhibitor%2C virus release protein%3B MC018%3B similar to VACV-WR C17L and VACV-Cop F11L;gbkey=CDS;gene=OPG055;locus_tag=NBT03_gp035;product=Protein F11;protein_id=YP_010377038.1 +NC_063383.1 RefSeq gene 37127 39034 . - . ID=gene-NBT03_gp036;Dbxref=GeneID:72551452;Name=OPG056;gbkey=Gene;gene=OPG056;gene_biotype=protein_coding;locus_tag=NBT03_gp036;old_locus_tag=MPXV-M5312_HM12_Rivers-040 +NC_063383.1 RefSeq CDS 37127 39034 . - 0 ID=cds-YP_010377039.1;Parent=gene-NBT03_gp036;Dbxref=GenBank:YP_010377039.1,GeneID:72551452;Name=OPG056;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp044%3B actin tail formation%3B EEV maturation protein%3B similar to VACV-WR C18L and VACV-Cop F12L;gbkey=CDS;gene=OPG056;locus_tag=NBT03_gp036;product=EEV maturation protein;protein_id=YP_010377039.1 +NC_063383.1 RefSeq gene 39077 40195 . - . ID=gene-NBT03_gp037;Dbxref=GeneID:72551453;Name=OPG057;gbkey=Gene;gene=OPG057;gene_biotype=protein_coding;locus_tag=NBT03_gp037;old_locus_tag=MPXV-M5312_HM12_Rivers-041 +NC_063383.1 RefSeq CDS 39077 40195 . - 0 ID=cds-YP_010377040.1;Parent=gene-NBT03_gp037;Dbxref=GenBank:YP_010377040.1,GeneID:72551453;Name=OPG057;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp045%3B major envelope antigen of EEV%3B wrapping of IMV to form IEV%3B phospholipase D-like%3B Palmitylated EEV membrane glycoprotein%3B similar to VACV-WR C19L and VACV-Cop F13L;gbkey=CDS;gene=OPG057;locus_tag=NBT03_gp037;product=Palmytilated EEV membrane protein;protein_id=YP_010377040.1 +NC_063383.1 RefSeq gene 40213 40434 . - . ID=gene-NBT03_gp038;Dbxref=GeneID:72551454;Name=OPG058;gbkey=Gene;gene=OPG058;gene_biotype=protein_coding;locus_tag=NBT03_gp038;old_locus_tag=MPXV-M5312_HM12_Rivers-042 +NC_063383.1 RefSeq CDS 40213 40434 . - 0 ID=cds-YP_010377041.1;Parent=gene-NBT03_gp038;Dbxref=GenBank:YP_010377041.1,GeneID:72551454;Name=OPG058;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp046%3B similar to VACV-WR C20L and VACV-Cop F14L;gbkey=CDS;gene=OPG058;locus_tag=NBT03_gp038;product=Protein F14 (1);protein_id=YP_010377041.1 +NC_063383.1 RefSeq gene 40484 40633 . - . ID=gene-NBT03_gp039;Dbxref=GeneID:72551455;Name=OPG059;gbkey=Gene;gene=OPG059;gene_biotype=protein_coding;locus_tag=NBT03_gp039;old_locus_tag=MPXV-M5312_HM12_Rivers-043 +NC_063383.1 RefSeq CDS 40484 40633 . - 0 ID=cds-YP_010377042.1;Parent=gene-NBT03_gp039;Dbxref=GenBank:YP_010377042.1,GeneID:72551455;Name=OPG059;Note=Taxonomic breadth: poxvirinae%3B IMV protein%3B C20.5L%3B similar to VACV-CopF14.5L;gbkey=CDS;gene=OPG059;locus_tag=NBT03_gp039;product=Cytochrome C oxidase;protein_id=YP_010377042.1 +NC_063383.1 RefSeq gene 40706 41182 . - . ID=gene-NBT03_gp040;Dbxref=GeneID:72551456;Name=OPG060;gbkey=Gene;gene=OPG060;gene_biotype=protein_coding;locus_tag=NBT03_gp040;old_locus_tag=MPXV-M5312_HM12_Rivers-044 +NC_063383.1 RefSeq CDS 40706 41182 . - 0 ID=cds-YP_010377043.1;Parent=gene-NBT03_gp040;Dbxref=GenBank:YP_010377043.1,GeneID:72551456;Name=OPG060;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp047%3B Unknown conserved protein%3B similar to VACV-WR C21L and VACV-Cop F15L;gbkey=CDS;gene=OPG060;locus_tag=NBT03_gp040;product=Protein F15;protein_id=YP_010377043.1 +NC_063383.1 RefSeq gene 41189 41884 . - . ID=gene-NBT03_gp041;Dbxref=GeneID:72551457;Name=OPG061;gbkey=Gene;gene=OPG061;gene_biotype=protein_coding;locus_tag=NBT03_gp041;old_locus_tag=MPXV-M5312_HM12_Rivers-045 +NC_063383.1 RefSeq CDS 41189 41884 . - 0 ID=cds-YP_010377044.1;Parent=gene-NBT03_gp041;Dbxref=GenBank:YP_010377044.1,GeneID:72551457;Name=OPG061;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp048%3B Non-functional Serine Recombinase%3B similar to VACV-WR C22L and VACV-Cop F16L;gbkey=CDS;gene=OPG061;locus_tag=NBT03_gp041;product=Protein F16 (1);protein_id=YP_010377044.1 +NC_063383.1 RefSeq gene 41947 42252 . + . ID=gene-NBT03_gp042;Dbxref=GeneID:72551458;Name=OPG062;gbkey=Gene;gene=OPG062;gene_biotype=protein_coding;locus_tag=NBT03_gp042;old_locus_tag=MPXV-M5312_HM12_Rivers-046 +NC_063383.1 RefSeq CDS 41947 42252 . + 0 ID=cds-YP_010377045.1;Parent=gene-NBT03_gp042;Dbxref=GenBank:YP_010377045.1,GeneID:72551458;Name=OPG062;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp049%3B virion core DNA-binding phosphoprotein (VP11)%3B mTOR antagonist%3B similar to VACV-WR C23R and VACV-Cop F17R;gbkey=CDS;gene=OPG062;locus_tag=NBT03_gp042;product=DNA-binding phosphoprotein (1);protein_id=YP_010377045.1 +NC_063383.1 RefSeq gene 42249 43688 . - . ID=gene-NBT03_gp043;Dbxref=GeneID:72551459;Name=OPG063;gbkey=Gene;gene=OPG063;gene_biotype=protein_coding;locus_tag=NBT03_gp043;old_locus_tag=MPXV-M5312_HM12_Rivers-047 +NC_063383.1 RefSeq CDS 42249 43688 . - 0 ID=cds-YP_010377046.1;Parent=gene-NBT03_gp043;Dbxref=GenBank:YP_010377046.1,GeneID:72551459;Name=OPG063;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp050%3B poly-A polymerase%2C Poly (A) polymerase catalytic subunit (VP55)%3B similar to VACV-WR F1L and VACV-Cop E1L;gbkey=CDS;gene=OPG063;locus_tag=NBT03_gp043;product=Poly(A) polymerase catalytic subunit (3);protein_id=YP_010377046.1 +NC_063383.1 RefSeq gene 43685 45898 . - . ID=gene-NBT03_gp044;Dbxref=GeneID:72551460;Name=OPG064;gbkey=Gene;gene=OPG064;gene_biotype=protein_coding;locus_tag=NBT03_gp044;old_locus_tag=MPXV-M5312_HM12_Rivers-048 +NC_063383.1 RefSeq CDS 43685 45898 . - 0 ID=cds-YP_010377047.1;Parent=gene-NBT03_gp044;Dbxref=GenBank:YP_010377047.1,GeneID:72551460;Name=OPG064;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp051%3B IEV morphogenesis%3B similar to VACV-WR F2L and VACV-Cop E2L;gbkey=CDS;gene=OPG064;locus_tag=NBT03_gp044;product=Iev morphogenesis protein;protein_id=YP_010377047.1 +NC_063383.1 RefSeq gene 46022 46483 . - . ID=gene-NBT03_gp045;Dbxref=GeneID:72551461;Name=OPG065;gbkey=Gene;gene=OPG065;gene_biotype=protein_coding;locus_tag=NBT03_gp045;old_locus_tag=MPXV-M5312_HM12_Rivers-049 +NC_063383.1 RefSeq CDS 46022 46483 . - 0 ID=cds-YP_010377048.1;Parent=gene-NBT03_gp045;Dbxref=GenBank:YP_010377048.1,GeneID:72551461;Name=OPG065;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp052%3B interferon resistance factor%3B two forms (25 kDa and 19 kDa) of the dsRNA-binding protein%3B inhibition of dsRNA-dependent protein kinase and 2-5A-synthet%3B dsRNA-binding protein%2C IFN resistance/PKR inhibitor (Z-DNA binding)%3B start of ORF is missing approx. 37 AA compared to CPXVs%3B similar to VACV-WR F3L and VACV-Cop E3L;gbkey=CDS;gene=OPG065;locus_tag=NBT03_gp045;product=Double-stranded RNA binding protein;protein_id=YP_010377048.1 +NC_063383.1 RefSeq gene 46649 47428 . - . ID=gene-NBT03_gp046;Dbxref=GeneID:72551462;Name=OPG066;gbkey=Gene;gene=OPG066;gene_biotype=protein_coding;locus_tag=NBT03_gp046;old_locus_tag=MPXV-M5312_HM12_Rivers-050 +NC_063383.1 RefSeq CDS 46649 47428 . - 0 ID=cds-YP_010377049.1;Parent=gene-NBT03_gp046;Dbxref=GenBank:YP_010377049.1,GeneID:72551462;Name=OPG066;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp053%3B RNA polymerase 30 kDa subunit (RPO30)%3B simultaneously intermediate stage promoter-specific transcription factor%2C VITF-1%3B similar to VACV-WR F4L and VACV-Cop E4L;gbkey=CDS;gene=OPG066;locus_tag=NBT03_gp046;product=DNA-directed RNA polymerase 30 kDa polypeptide;protein_id=YP_010377049.1 +NC_063383.1 RefSeq sequence_feature 47525 48062 . + . ID=id-NC_063383.1:47525..48062;exon_number=OPG067;gbkey=misc_feature;number=OPG067 +NC_063383.1 RefSeq gene 48201 49904 . + . ID=gene-NBT03_gp047;Dbxref=GeneID:72551463;Name=OPG068;gbkey=Gene;gene=OPG068;gene_biotype=protein_coding;locus_tag=NBT03_gp047;old_locus_tag=MPXV-M5312_HM12_Rivers-052 +NC_063383.1 RefSeq CDS 48201 49904 . + 0 ID=cds-YP_010377051.1;Parent=gene-NBT03_gp047;Dbxref=GenBank:YP_010377051.1,GeneID:72551463;Name=OPG068;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp054%3B Virion protein%3B similar to VACV-WR F5R and VACV-Cop E6R;gbkey=CDS;gene=OPG068;locus_tag=NBT03_gp047;product=IMV membrane protein E6;protein_id=YP_010377051.1 +NC_063383.1 RefSeq gene 49986 50486 . + . ID=gene-NBT03_gp048;Dbxref=GeneID:72551464;Name=OPG069;gbkey=Gene;gene=OPG069;gene_biotype=protein_coding;locus_tag=NBT03_gp048;old_locus_tag=MPXV-M5312_HM12_Rivers-053 +NC_063383.1 RefSeq CDS 49986 50486 . + 0 ID=cds-YP_010377052.1;Parent=gene-NBT03_gp048;Dbxref=GenBank:YP_010377052.1,GeneID:72551464;Name=OPG069;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp055%3B soluble myristylated protein%3B similar to VACV-WR F6R and VACV-Cop E7R;gbkey=CDS;gene=OPG069;locus_tag=NBT03_gp048;product=Myristoylated protein E7;protein_id=YP_010377052.1 +NC_063383.1 RefSeq gene 50590 51411 . + . ID=gene-NBT03_gp049;Dbxref=GeneID:72551465;Name=OPG070;gbkey=Gene;gene=OPG070;gene_biotype=protein_coding;locus_tag=NBT03_gp049;old_locus_tag=MPXV-M5312_HM12_Rivers-054 +NC_063383.1 RefSeq CDS 50590 51411 . + 0 ID=cds-YP_010377053.1;Parent=gene-NBT03_gp049;Dbxref=GenBank:YP_010377053.1,GeneID:72551465;Name=OPG070;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp056%3B ER-localized membrane protein%2C virion core protein%3B similar to VACV-WR F7R and VACV-Cop E8R;gbkey=CDS;gene=OPG070;locus_tag=NBT03_gp049;product=Membrane protein E8;protein_id=YP_010377053.1 +NC_063383.1 RefSeq gene 51418 54438 . - . ID=gene-NBT03_gp050;Dbxref=GeneID:72551466;Name=OPG071;gbkey=Gene;gene=OPG071;gene_biotype=protein_coding;locus_tag=NBT03_gp050;old_locus_tag=MPXV-M5312_HM12_Rivers-055 +NC_063383.1 RefSeq CDS 51418 54438 . - 0 ID=cds-YP_010377054.1;Parent=gene-NBT03_gp050;Dbxref=GenBank:YP_010377054.1,GeneID:72551466;Name=OPG071;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp057%3B DNA polymerase%2C catalytic subunit%3B similar to VACV-WR F8L and VACV-Cop E9L;gbkey=CDS;gene=OPG071;locus_tag=NBT03_gp050;product=DNA polymerase (2);protein_id=YP_010377054.1 +NC_063383.1 RefSeq gene 54470 54757 . + . ID=gene-NBT03_gp051;Dbxref=GeneID:72551467;Name=OPG072;gbkey=Gene;gene=OPG072;gene_biotype=protein_coding;locus_tag=NBT03_gp051;old_locus_tag=MPXV-M5312_HM12_Rivers-056 +NC_063383.1 RefSeq CDS 54470 54757 . + 0 ID=cds-YP_010377055.1;Parent=gene-NBT03_gp051;Dbxref=GenBank:YP_010377055.1,GeneID:72551467;Name=OPG072;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp058%3B protein disulfide bond-forming enzyme%3B Sulfhydryl oxidase (FAD-linked)%3B similar to VACV-WR F9R and VACV-Cop E10R;gbkey=CDS;gene=OPG072;locus_tag=NBT03_gp051;product=Sulfhydryl oxidase;protein_id=YP_010377055.1 +NC_063383.1 RefSeq gene 54752 55141 . - . ID=gene-NBT03_gp052;Dbxref=GeneID:72551468;Name=OPG073;gbkey=Gene;gene=OPG073;gene_biotype=protein_coding;locus_tag=NBT03_gp052;old_locus_tag=MPXV-M5312_HM12_Rivers-057 +NC_063383.1 RefSeq CDS 54752 55141 . - 0 ID=cds-YP_010377056.1;Parent=gene-NBT03_gp052;Dbxref=GenBank:YP_010377056.1,GeneID:72551468;Name=OPG073;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp059%3B virion core protein%3B similar to VACV-WR F10L and VACV-Cop E11L;gbkey=CDS;gene=OPG073;locus_tag=NBT03_gp052;product=Virion core protein E11;protein_id=YP_010377056.1 +NC_063383.1 RefSeq gene 55128 57125 . - . ID=gene-NBT03_gp053;Dbxref=GeneID:72551469;Name=OPG074;gbkey=Gene;gene=OPG074;gene_biotype=protein_coding;locus_tag=NBT03_gp053;old_locus_tag=MPXV-M5312_HM12_Rivers-058 +NC_063383.1 RefSeq CDS 55128 57125 . - 0 ID=cds-YP_010377057.1;Parent=gene-NBT03_gp053;Dbxref=GenBank:YP_010377057.1,GeneID:72551469;Name=OPG074;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp060%3B Membrane protein%3B similar to VACV-WR Q1L and VACV-Cop O1L;gbkey=CDS;gene=OPG074;locus_tag=NBT03_gp053;product=Iev morphogenesis protein;protein_id=YP_010377057.1 +NC_063383.1 RefSeq gene 57172 57498 . - . ID=gene-NBT03_gp054;Dbxref=GeneID:72551470;Name=OPG075;gbkey=Gene;gene=OPG075;gene_biotype=protein_coding;locus_tag=NBT03_gp054;old_locus_tag=MPXV-M5312_HM12_Rivers-059 +NC_063383.1 RefSeq CDS 57172 57498 . - 0 ID=cds-YP_010377058.1;Parent=gene-NBT03_gp054;Dbxref=GenBank:YP_010377058.1,GeneID:72551470;Name=OPG075;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp061%3B virion-associated glutaredoxin%3B glutaredoxin 1%3B similar to VACV-WR Q2L and VACV-Cop O2L;gbkey=CDS;gene=OPG075;locus_tag=NBT03_gp054;product=Glutaredoxin-1;protein_id=YP_010377058.1 +NC_063383.1 RefSeq gene 57523 57630 . - . ID=gene-NBT03_gp055;Dbxref=GeneID:72551471;Name=OPG076;gbkey=Gene;gene=OPG076;gene_biotype=protein_coding;locus_tag=NBT03_gp055 +NC_063383.1 RefSeq CDS 57523 57630 . - 0 ID=cds-YP_010377183.1;Parent=gene-NBT03_gp055;Dbxref=GenBank:YP_010377183.1,GeneID:72551471;Name=OPG076;gbkey=CDS;gene=OPG076;locus_tag=NBT03_gp055;product=MV membrane EFC component;protein_id=YP_010377183.1 +NC_063383.1 RefSeq gene 57645 58583 . - . ID=gene-NBT03_gp056;Dbxref=GeneID:72551472;Name=OPG077;gbkey=Gene;gene=OPG077;gene_biotype=protein_coding;locus_tag=NBT03_gp056;old_locus_tag=MPXV-M5312_HM12_Rivers-060 +NC_063383.1 RefSeq CDS 57645 58583 . - 0 ID=cds-YP_010377059.1;Parent=gene-NBT03_gp056;Dbxref=GenBank:YP_010377059.1,GeneID:72551472;Name=OPG077;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp062%3B virosomal protein essential for virus multiplication%3B DNA-binding core protein%3B similar to VACV-WR I1L and VACV-Cop I1L;gbkey=CDS;gene=OPG077;locus_tag=NBT03_gp056;product=Telomere-binding protein I1;protein_id=YP_010377059.1 +NC_063383.1 RefSeq gene 58590 58811 . - . ID=gene-NBT03_gp057;Dbxref=GeneID:72551473;Name=OPG078;gbkey=Gene;gene=OPG078;gene_biotype=protein_coding;locus_tag=NBT03_gp057;old_locus_tag=MPXV-M5312_HM12_Rivers-061 +NC_063383.1 RefSeq CDS 58590 58811 . - 0 ID=cds-YP_010377060.1;Parent=gene-NBT03_gp057;Dbxref=GenBank:YP_010377060.1,GeneID:72551473;Name=OPG078;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp063%3B IMV membrane protein%3B similar to VACV-WR I2L and VACV-Cop I2L;gbkey=CDS;gene=OPG078;locus_tag=NBT03_gp057;product=IMV membrane protein I2;protein_id=YP_010377060.1 +NC_063383.1 RefSeq gene 58812 59621 . - . ID=gene-NBT03_gp058;Dbxref=GeneID:72551474;Name=OPG079;gbkey=Gene;gene=OPG079;gene_biotype=protein_coding;locus_tag=NBT03_gp058;old_locus_tag=MPXV-M5312_HM12_Rivers-062 +NC_063383.1 RefSeq CDS 58812 59621 . - 0 ID=cds-YP_010377061.1;Parent=gene-NBT03_gp058;Dbxref=GenBank:YP_010377061.1,GeneID:72551474;Name=OPG079;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp064%3B virosomal ssDNA-binding phosphoprotein%3B interacts with R2 subunit of ribonucleotide reductase%3B similar to VACV-WR I3L and VACV-Cop I3L;gbkey=CDS;gene=OPG079;locus_tag=NBT03_gp058;product=DNA-binding phosphoprotein (2);protein_id=YP_010377061.1 +NC_063383.1 RefSeq gene 59703 62018 . - . ID=gene-NBT03_gp059;Dbxref=GeneID:72551475;Name=OPG080;gbkey=Gene;gene=OPG080;gene_biotype=protein_coding;locus_tag=NBT03_gp059;old_locus_tag=MPXV-M5312_HM12_Rivers-063 +NC_063383.1 RefSeq CDS 59703 62018 . - 0 ID=cds-YP_010377062.1;Parent=gene-NBT03_gp059;Dbxref=GenBank:YP_010377062.1,GeneID:72551475;Name=OPG080;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp065%3B ribonucleotide reductase%2C large subunit%2C R1%3B similar to VACV-WR I4L and VACV-Cop I4L;gbkey=CDS;gene=OPG080;locus_tag=NBT03_gp059;product=Ribonucleoside-diphosphate reductase (2);protein_id=YP_010377062.1 +NC_063383.1 RefSeq gene 62046 62285 . - . ID=gene-NBT03_gp060;Dbxref=GeneID:72551476;Name=OPG081;gbkey=Gene;gene=OPG081;gene_biotype=protein_coding;locus_tag=NBT03_gp060;old_locus_tag=MPXV-M5312_HM12_Rivers-064 +NC_063383.1 RefSeq CDS 62046 62285 . - 0 ID=cds-YP_010377063.1;Parent=gene-NBT03_gp060;Dbxref=GenBank:YP_010377063.1,GeneID:72551476;Name=OPG081;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp066%3B IMV surface membrane protein%2C VP13%3B similar to VACV-WR I5L and VACV-Cop I5L;gbkey=CDS;gene=OPG081;locus_tag=NBT03_gp060;product=IMV membrane protein I5;protein_id=YP_010377063.1 +NC_063383.1 RefSeq gene 62304 63452 . - . ID=gene-NBT03_gp061;Dbxref=GeneID:72551477;Name=OPG082;gbkey=Gene;gene=OPG082;gene_biotype=protein_coding;locus_tag=NBT03_gp061;old_locus_tag=MPXV-M5312_HM12_Rivers-065 +NC_063383.1 RefSeq CDS 62304 63452 . - 0 ID=cds-YP_010377064.1;Parent=gene-NBT03_gp061;Dbxref=GenBank:YP_010377064.1,GeneID:72551477;Name=OPG082;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp067%3B Telomere-binding protein%3B similar to VACV-WR I6L and VACV-Cop I6L;gbkey=CDS;gene=OPG082;locus_tag=NBT03_gp061;product=Telomere-binding protein;protein_id=YP_010377064.1 +NC_063383.1 RefSeq gene 63445 64716 . - . ID=gene-NBT03_gp062;Dbxref=GeneID:72551478;Name=OPG083;gbkey=Gene;gene=OPG083;gene_biotype=protein_coding;locus_tag=NBT03_gp062;old_locus_tag=MPXV-M5312_HM12_Rivers-066 +NC_063383.1 RefSeq CDS 63445 64716 . - 0 ID=cds-YP_010377065.1;Parent=gene-NBT03_gp062;Dbxref=GenBank:YP_010377065.1,GeneID:72551478;Name=OPG083;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp068%3B virion core protein%3B similar to DNA topoisomerase II%3B Virion core cysteine protease%3B similar to VACV-WR I7L and VACV-Cop I7L;gbkey=CDS;gene=OPG083;locus_tag=NBT03_gp062;product=Viral core cysteine proteinase;protein_id=YP_010377065.1 +NC_063383.1 RefSeq gene 64722 66752 . + . ID=gene-NBT03_gp063;Dbxref=GeneID:72551479;Name=OPG084;gbkey=Gene;gene=OPG084;gene_biotype=protein_coding;locus_tag=NBT03_gp063;old_locus_tag=MPXV-M5312_HM12_Rivers-067 +NC_063383.1 RefSeq CDS 64722 66752 . + 0 ID=cds-YP_010377066.1;Parent=gene-NBT03_gp063;Dbxref=GenBank:YP_010377066.1,GeneID:72551479;Name=OPG084;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp069%3B nucleoside triphosphate phosphohydrolase II%2C NPH-II%3B DNA and RNA helicase%3B DExH-NPH-II domain%3B similar to VACV-WR I8R and VACV-Cop I8R;gbkey=CDS;gene=OPG084;locus_tag=NBT03_gp063;product=RNA helicase NPH-II (2);protein_id=YP_010377066.1 +NC_063383.1 RefSeq gene 66756 68531 . - . ID=gene-NBT03_gp064;Dbxref=GeneID:72551480;Name=OPG085;gbkey=Gene;gene=OPG085;gene_biotype=protein_coding;locus_tag=NBT03_gp064;old_locus_tag=MPXV-M5312_HM12_Rivers-068 +NC_063383.1 RefSeq CDS 66756 68531 . - 0 ID=cds-YP_010377067.1;Parent=gene-NBT03_gp064;Dbxref=GenBank:YP_010377067.1,GeneID:72551480;Name=OPG085;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp070%3B proteinase%3B Metalloprotease%3B similar to VACV-WR G1L and VACV-Cop G1L;gbkey=CDS;gene=OPG085;locus_tag=NBT03_gp064;product=Metalloendopeptidase;protein_id=YP_010377067.1 +NC_063383.1 RefSeq gene 68528 68863 . - . ID=gene-NBT03_gp065;Dbxref=GeneID:72551481;Name=OPG086;gbkey=Gene;gene=OPG086;gene_biotype=protein_coding;locus_tag=NBT03_gp065;old_locus_tag=MPXV-M5312_HM12_Rivers-069 +NC_063383.1 RefSeq CDS 68528 68863 . - 0 ID=cds-YP_010377068.1;Parent=gene-NBT03_gp065;Dbxref=GenBank:YP_010377068.1,GeneID:72551481;Name=OPG086;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp071%3B Entry/fusion complex component%3B similar to VACV-WR G2L and VACV-Cop G3L;gbkey=CDS;gene=OPG086;locus_tag=NBT03_gp065;product=Entry/fusion complex component;protein_id=YP_010377068.1 +NC_063383.1 RefSeq gene 68857 69519 . + . ID=gene-NBT03_gp066;Dbxref=GeneID:72551482;Name=OPG087;gbkey=Gene;gene=OPG087;gene_biotype=protein_coding;locus_tag=NBT03_gp066;old_locus_tag=MPXV-M5312_HM12_Rivers-070 +NC_063383.1 RefSeq CDS 68857 69519 . + 0 ID=cds-YP_010377069.1;Parent=gene-NBT03_gp066;Dbxref=GenBank:YP_010377069.1,GeneID:72551482;Name=OPG087;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp072%3B VLTF (late transcription elongation factor)%3B similar to VACV-WR G3R and VACV-Cop G2R;gbkey=CDS;gene=OPG087;locus_tag=NBT03_gp066;product=Late transcription elongation factor;protein_id=YP_010377069.1 +NC_063383.1 RefSeq gene 69489 69863 . - . ID=gene-NBT03_gp067;Dbxref=GeneID:72551483;Name=OPG088;gbkey=Gene;gene=OPG088;gene_biotype=protein_coding;locus_tag=NBT03_gp067;old_locus_tag=MPXV-M5312_HM12_Rivers-071 +NC_063383.1 RefSeq CDS 69489 69863 . - 0 ID=cds-YP_010377070.1;Parent=gene-NBT03_gp067;Dbxref=GenBank:YP_010377070.1,GeneID:72551483;Name=OPG088;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp073%3B virion-associated glutaredoxin%3B Glutaredoxin-like protein%3B similar to VACV-WR G4L and VACV-Cop G4L;gbkey=CDS;gene=OPG088;locus_tag=NBT03_gp067;product=Glutaredoxin-2;protein_id=YP_010377070.1 +NC_063383.1 RefSeq gene 69866 71170 . + . ID=gene-NBT03_gp068;Dbxref=GeneID:72551484;Name=OPG089;gbkey=Gene;gene=OPG089;gene_biotype=protein_coding;locus_tag=NBT03_gp068;old_locus_tag=MPXV-M5312_HM12_Rivers-072 +NC_063383.1 RefSeq CDS 69866 71170 . + 0 ID=cds-YP_010377071.1;Parent=gene-NBT03_gp068;Dbxref=GenBank:YP_010377071.1,GeneID:72551484;Name=OPG089;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp074%3B FEN1-like nuclease%3B similar to VACV-WR G5R and VACV-Cop G5R;gbkey=CDS;gene=OPG089;locus_tag=NBT03_gp068;product=FEN1-like nuclease;protein_id=YP_010377071.1 +NC_063383.1 RefSeq gene 71179 71370 . + . ID=gene-NBT03_gp069;Dbxref=GeneID:72551485;Name=OPG090;gbkey=Gene;gene=OPG090;gene_biotype=protein_coding;locus_tag=NBT03_gp069;old_locus_tag=MPXV-M5312_HM12_Rivers-073 +NC_063383.1 RefSeq CDS 71179 71370 . + 0 ID=cds-YP_010377072.1;Parent=gene-NBT03_gp069;Dbxref=GenBank:YP_010377072.1,GeneID:72551485;Name=OPG090;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp075%3B RNA polymerase subunit%2C 7 kDa subunit (RPO7)%3B similar to VACV-WR G6R and VACV-Cop G5.5R;gbkey=CDS;gene=OPG090;locus_tag=NBT03_gp069;product=DNA-directed RNA polymerase 7 kDa subunit;protein_id=YP_010377072.1 +NC_063383.1 RefSeq gene 71370 71867 . + . ID=gene-NBT03_gp070;Dbxref=GeneID:72551486;Name=OPG091;gbkey=Gene;gene=OPG091;gene_biotype=protein_coding;locus_tag=NBT03_gp070;old_locus_tag=MPXV-M5312_HM12_Rivers-074 +NC_063383.1 RefSeq CDS 71370 71867 . + 0 ID=cds-YP_010377073.1;Parent=gene-NBT03_gp070;Dbxref=GenBank:YP_010377073.1,GeneID:72551486;Name=OPG091;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp076%3B NLPc/P60 superfamily protein%3B similar to VACV-WR G7R and VACV-Cop G6R;gbkey=CDS;gene=OPG091;locus_tag=NBT03_gp070;product=Nlpc/p60 superfamily protein;protein_id=YP_010377073.1 +NC_063383.1 RefSeq gene 71832 72947 . - . ID=gene-NBT03_gp071;Dbxref=GeneID:72551487;Name=OPG092;gbkey=Gene;gene=OPG092;gene_biotype=protein_coding;locus_tag=NBT03_gp071;old_locus_tag=MPXV-M5312_HM12_Rivers-075 +NC_063383.1 RefSeq CDS 71832 72947 . - 0 ID=cds-YP_010377074.1;Parent=gene-NBT03_gp071;Dbxref=GenBank:YP_010377074.1,GeneID:72551487;Name=OPG092;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp077%3B virion protein%3B Virion phosphoprotein%2C early morphogenesis%3B similar to VACV-WR G8L and VACV-Cop G7L;gbkey=CDS;gene=OPG092;locus_tag=NBT03_gp071;product=Assembly protein G7;protein_id=YP_010377074.1 +NC_063383.1 RefSeq gene 72978 73760 . + . ID=gene-NBT03_gp072;Dbxref=GeneID:72551488;Name=OPG093;gbkey=Gene;gene=OPG093;gene_biotype=protein_coding;locus_tag=NBT03_gp072;old_locus_tag=MPXV-M5312_HM12_Rivers-076 +NC_063383.1 RefSeq CDS 72978 73760 . + 0 ID=cds-YP_010377075.1;Parent=gene-NBT03_gp072;Dbxref=GenBank:YP_010377075.1,GeneID:72551488;Name=OPG093;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp078%3B late gene transcription factor%2C VLTF-1%3B similar to VACV-WR G9R and VACV-Cop G8R;gbkey=CDS;gene=OPG093;locus_tag=NBT03_gp072;product=Late transcription factor VLTF-1;protein_id=YP_010377075.1 +NC_063383.1 RefSeq gene 73780 74802 . + . ID=gene-NBT03_gp073;Dbxref=GeneID:72551489;Name=OPG094;gbkey=Gene;gene=OPG094;gene_biotype=protein_coding;locus_tag=NBT03_gp073;old_locus_tag=MPXV-M5312_HM12_Rivers-077 +NC_063383.1 RefSeq CDS 73780 74802 . + 0 ID=cds-YP_010377076.1;Parent=gene-NBT03_gp073;Dbxref=GenBank:YP_010377076.1,GeneID:72551489;Name=OPG094;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp079%3B myristylated protein%3B Entry/fusion complex component%2C myristylprotein%3B similar to VACV-WR G10R and VACV-Cop G9R;gbkey=CDS;gene=OPG094;locus_tag=NBT03_gp073;product=Myristylated protein;protein_id=YP_010377076.1 +NC_063383.1 RefSeq gene 74803 75555 . + . ID=gene-NBT03_gp074;Dbxref=GeneID:72551490;Name=OPG095;gbkey=Gene;gene=OPG095;gene_biotype=protein_coding;locus_tag=NBT03_gp074;old_locus_tag=MPXV-M5312_HM12_Rivers-078 +NC_063383.1 RefSeq CDS 74803 75555 . + 0 ID=cds-YP_010377077.1;Parent=gene-NBT03_gp074;Dbxref=GenBank:YP_010377077.1,GeneID:72551490;Name=OPG095;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp080%3B myristylated IMV surface membrane protein%3B similar to VACV-WR M1R and VACV-Cop L1R;gbkey=CDS;gene=OPG095;locus_tag=NBT03_gp074;product=IMV membrane protein L1R;protein_id=YP_010377077.1 +NC_063383.1 RefSeq gene 75587 75865 . + . ID=gene-NBT03_gp075;Dbxref=GeneID:72551491;Name=OPG096;gbkey=Gene;gene=OPG096;gene_biotype=protein_coding;locus_tag=NBT03_gp075;old_locus_tag=MPXV-M5312_HM12_Rivers-079 +NC_063383.1 RefSeq CDS 75587 75865 . + 0 ID=cds-YP_010377078.1;Parent=gene-NBT03_gp075;Dbxref=GenBank:YP_010377078.1,GeneID:72551491;Name=OPG096;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp081%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR M2R and VACV-Cop L2R;gbkey=CDS;gene=OPG096;locus_tag=NBT03_gp075;product=Crescent membrane and immature virion formation protein;protein_id=YP_010377078.1 +NC_063383.1 RefSeq gene 75841 76875 . - . ID=gene-NBT03_gp076;Dbxref=GeneID:72551492;Name=OPG097;gbkey=Gene;gene=OPG097;gene_biotype=protein_coding;locus_tag=NBT03_gp076;old_locus_tag=MPXV-M5312_HM12_Rivers-080 +NC_063383.1 RefSeq CDS 75841 76875 . - 0 ID=cds-YP_010377079.1;Parent=gene-NBT03_gp076;Dbxref=GenBank:YP_010377079.1,GeneID:72551492;Name=OPG097;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp082%3B Internal virion protein%3B similar to VACV-WR M3L and VACV-Cop L3L;gbkey=CDS;gene=OPG097;locus_tag=NBT03_gp076;product=Internal virion L3/FP4 protein;protein_id=YP_010377079.1 +NC_063383.1 RefSeq gene 76900 77655 . + . ID=gene-NBT03_gp077;Dbxref=GeneID:72551493;Name=OPG098;gbkey=Gene;gene=OPG098;gene_biotype=protein_coding;locus_tag=NBT03_gp077;old_locus_tag=MPXV-M5312_HM12_Rivers-081 +NC_063383.1 RefSeq CDS 76900 77655 . + 0 ID=cds-YP_010377080.1;Parent=gene-NBT03_gp077;Dbxref=GenBank:YP_010377080.1,GeneID:72551493;Name=OPG098;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp083%3B virion core protein vp8%3B stimulation of I8R helicase activity%3B ss/dsDNA binding protein (VP8)%3B similar to VACV-WR M4R and VACV-Cop L4R;gbkey=CDS;gene=OPG098;locus_tag=NBT03_gp077;product=Nucleic acid binding protein VP8/L4R;protein_id=YP_010377080.1 +NC_063383.1 RefSeq gene 77665 78051 . + . ID=gene-NBT03_gp078;Dbxref=GeneID:72551494;Name=OPG099;gbkey=Gene;gene=OPG099;gene_biotype=protein_coding;locus_tag=NBT03_gp078;old_locus_tag=MPXV-M5312_HM12_Rivers-082 +NC_063383.1 RefSeq CDS 77665 78051 . + 0 ID=cds-YP_010377081.1;Parent=gene-NBT03_gp078;Dbxref=GenBank:YP_010377081.1,GeneID:72551494;Name=OPG099;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp084%3B Entry and Fusion IMV protein%3B similar to VACV-WR M5R and VACV-Cop L5R;gbkey=CDS;gene=OPG099;locus_tag=NBT03_gp078;product=Membrane protein CL5;protein_id=YP_010377081.1 +NC_063383.1 RefSeq gene 78008 78466 . + . ID=gene-NBT03_gp079;Dbxref=GeneID:72551495;Name=OPG100;gbkey=Gene;gene=OPG100;gene_biotype=protein_coding;locus_tag=NBT03_gp079;old_locus_tag=MPXV-M5312_HM12_Rivers-083 +NC_063383.1 RefSeq CDS 78008 78466 . + 0 ID=cds-YP_010377082.1;Parent=gene-NBT03_gp079;Dbxref=GenBank:YP_010377082.1,GeneID:72551495;Name=OPG100;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp085%3B Virion morph%3B similar to VACV-WR L1R and VACV-Cop J1R;gbkey=CDS;gene=OPG100;locus_tag=NBT03_gp079;product=IMV membrane protein J1;protein_id=YP_010377082.1 +NC_063383.1 RefSeq gene 78486 79019 . + . ID=gene-NBT03_gp080;Dbxref=GeneID:72551496;Name=OPG101;gbkey=Gene;gene=OPG101;gene_biotype=protein_coding;locus_tag=NBT03_gp080;old_locus_tag=MPXV-M5312_HM12_Rivers-084 +NC_063383.1 RefSeq CDS 78486 79019 . + 0 ID=cds-YP_010377083.1;Parent=gene-NBT03_gp080;Dbxref=GenBank:YP_010377083.1,GeneID:72551496;Name=OPG101;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp086%3B thymidine kinase%3B similar to VACV-WR L2R and VACV-Cop J2R;gbkey=CDS;gene=OPG101;locus_tag=NBT03_gp080;product=Thymidine kinase;protein_id=YP_010377083.1 +NC_063383.1 RefSeq gene 79085 80086 . + . ID=gene-NBT03_gp081;Dbxref=GeneID:72551497;Name=OPG102;gbkey=Gene;gene=OPG102;gene_biotype=protein_coding;locus_tag=NBT03_gp081;old_locus_tag=MPXV-M5312_HM12_Rivers-085 +NC_063383.1 RefSeq CDS 79085 80086 . + 0 ID=cds-YP_010377084.1;Parent=gene-NBT03_gp081;Dbxref=GenBank:YP_010377084.1,GeneID:72551497;Name=OPG102;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp087%3B poly-A polymerase%2C stimulatory subunit%2C simultaneously cap-specific mRNA (nucleoside-O2'-)-methyltransferase%3B Poly (A) polymerase small subunit (VP39)%3B similar to VACV-WR L3R and VACV-Cop J3R;gbkey=CDS;gene=OPG102;locus_tag=NBT03_gp081;product=Cap-specific mRNA;protein_id=YP_010377084.1 +NC_063383.1 RefSeq gene 80001 80558 . + . ID=gene-NBT03_gp082;Dbxref=GeneID:72551498;Name=OPG103;gbkey=Gene;gene=OPG103;gene_biotype=protein_coding;locus_tag=NBT03_gp082;old_locus_tag=MPXV-M5312_HM12_Rivers-086 +NC_063383.1 RefSeq CDS 80001 80558 . + 0 ID=cds-YP_010377085.1;Parent=gene-NBT03_gp082;Dbxref=GenBank:YP_010377085.1,GeneID:72551498;Name=OPG103;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp088%3B RNA polymerase%2C 22 kDa subunit (RPO22)%3B similar to VACV-WR L4R and VACV-Cop J4R;gbkey=CDS;gene=OPG103;locus_tag=NBT03_gp082;product=DNA-directed RNA polymerase subunit;protein_id=YP_010377085.1 +NC_063383.1 RefSeq gene 80618 81019 . - . ID=gene-NBT03_gp083;Dbxref=GeneID:72551499;Name=OPG104;gbkey=Gene;gene=OPG104;gene_biotype=protein_coding;locus_tag=NBT03_gp083;old_locus_tag=MPXV-M5312_HM12_Rivers-087 +NC_063383.1 RefSeq CDS 80618 81019 . - 0 ID=cds-YP_010377086.1;Parent=gene-NBT03_gp083;Dbxref=GenBank:YP_010377086.1,GeneID:72551499;Name=OPG104;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp089%3B essential for virus multiplication%3B IMV membrane protein%3B similar to VACV-WR L5L and VACV-Cop J5L;gbkey=CDS;gene=OPG104;locus_tag=NBT03_gp083;product=Myristylated protein;protein_id=YP_010377086.1 +NC_063383.1 RefSeq gene 81126 84986 . + . ID=gene-NBT03_gp084;Dbxref=GeneID:72551500;Name=OPG105;gbkey=Gene;gene=OPG105;gene_biotype=protein_coding;locus_tag=NBT03_gp084;old_locus_tag=MPXV-M5312_HM12_Rivers-088 +NC_063383.1 RefSeq CDS 81126 84986 . + 0 ID=cds-YP_010377087.1;Parent=gene-NBT03_gp084;Dbxref=GenBank:YP_010377087.1,GeneID:72551500;Name=OPG105;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp090%3B RNA polymerase%2C 147 kDa subunit (RPO147)%3B similar to VACV-WR L6R and VACV-Cop J6R;gbkey=CDS;gene=OPG105;locus_tag=NBT03_gp084;product=DNA-dependent RNA polymerase subunit rpo147;protein_id=YP_010377087.1 +NC_063383.1 RefSeq gene 84983 85498 . - . ID=gene-NBT03_gp085;Dbxref=GeneID:72551501;Name=OPG106;gbkey=Gene;gene=OPG106;gene_biotype=protein_coding;locus_tag=NBT03_gp085;old_locus_tag=MPXV-M5312_HM12_Rivers-089 +NC_063383.1 RefSeq CDS 84983 85498 . - 0 ID=cds-YP_010377088.1;Parent=gene-NBT03_gp085;Dbxref=GenBank:YP_010377088.1,GeneID:72551501;Name=OPG106;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp091%3B tyrosine%3B Tyr/Ser phosphatase%2C IFN-gamma inhibitor%3B similar to VACV-WR H1L and VACV-Cop H1L;gbkey=CDS;gene=OPG106;locus_tag=NBT03_gp085;product=Tyr/ser protein phosphatase;protein_id=YP_010377088.1 +NC_063383.1 RefSeq gene 85512 86081 . + . ID=gene-NBT03_gp086;Dbxref=GeneID:72551502;Name=OPG107;gbkey=Gene;gene=OPG107;gene_biotype=protein_coding;locus_tag=NBT03_gp086;old_locus_tag=MPXV-M5312_HM12_Rivers-090 +NC_063383.1 RefSeq CDS 85512 86081 . + 0 ID=cds-YP_010377089.1;Parent=gene-NBT03_gp086;Dbxref=GenBank:YP_010377089.1,GeneID:72551502;Name=OPG107;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp092%3B IMV membrane protein%3B similar to VACV-WR H2R and VACV-Cop H2R;gbkey=CDS;gene=OPG107;locus_tag=NBT03_gp086;product=Entry-fusion complex essential component;protein_id=YP_010377089.1 +NC_063383.1 RefSeq gene 86085 87059 . - . ID=gene-NBT03_gp087;Dbxref=GeneID:72551503;Name=OPG108;gbkey=Gene;gene=OPG108;gene_biotype=protein_coding;locus_tag=NBT03_gp087;old_locus_tag=MPXV-M5312_HM12_Rivers-091 +NC_063383.1 RefSeq CDS 86085 87059 . - 0 ID=cds-YP_010377090.1;Parent=gene-NBT03_gp087;Dbxref=GenBank:YP_010377090.1,GeneID:72551503;Name=OPG108;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp093%3B IMV surface membrane protein%3B IMV heparin binding surface protein%3B similar to VACV-WR H3L and VACV-Cop H3L;gbkey=CDS;gene=OPG108;locus_tag=NBT03_gp087;product=IMV heparin binding surface protein;protein_id=YP_010377090.1 +NC_063383.1 RefSeq gene 87060 89447 . - . ID=gene-NBT03_gp088;Dbxref=GeneID:72551504;Name=OPG109;gbkey=Gene;gene=OPG109;gene_biotype=protein_coding;locus_tag=NBT03_gp088;old_locus_tag=MPXV-M5312_HM12_Rivers-092 +NC_063383.1 RefSeq CDS 87060 89447 . - 0 ID=cds-YP_010377091.1;Parent=gene-NBT03_gp088;Dbxref=GenBank:YP_010377091.1,GeneID:72551504;Name=OPG109;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp094%3B virion core RNA polymerase-associated protein%2C RAP94%3B similar to VACV-WR H4L and VACV-Cop H4L;gbkey=CDS;gene=OPG109;locus_tag=NBT03_gp088;product=RNA polymerase-associated transcription-specificity factor RAP94;protein_id=YP_010377091.1 +NC_063383.1 RefSeq gene 89632 90264 . + . ID=gene-NBT03_gp089;Dbxref=GeneID:72551505;Name=OPG110;gbkey=Gene;gene=OPG110;gene_biotype=protein_coding;locus_tag=NBT03_gp089;old_locus_tag=MPXV-M5312_HM12_Rivers-093 +NC_063383.1 RefSeq CDS 89632 90264 . + 0 ID=cds-YP_010377092.1;Parent=gene-NBT03_gp089;Dbxref=GenBank:YP_010377092.1,GeneID:72551505;Name=OPG110;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp095%3B virosome-associated late gene transcription factor%2C VLTF-4%3B Ca2+-binding motif%3B similar to VACV-WR H5R and VACV-Cop H5R;gbkey=CDS;gene=OPG110;locus_tag=NBT03_gp089;product=Late transcription factor VLTF-4 (1);protein_id=YP_010377092.1 +NC_063383.1 RefSeq gene 90265 91209 . + . ID=gene-NBT03_gp090;Dbxref=GeneID:72551506;Name=OPG111;gbkey=Gene;gene=OPG111;gene_biotype=protein_coding;locus_tag=NBT03_gp090;old_locus_tag=MPXV-M5312_HM12_Rivers-094 +NC_063383.1 RefSeq CDS 90265 91209 . + 0 ID=cds-YP_010377093.1;Parent=gene-NBT03_gp090;Dbxref=GenBank:YP_010377093.1,GeneID:72551506;Name=OPG111;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp096%3B DNA topoisomerase type I%3B similar to VACV-WR H6R and VACV-Cop H6R;gbkey=CDS;gene=OPG111;locus_tag=NBT03_gp090;product=DNA topoisomerase type I;protein_id=YP_010377093.1 +NC_063383.1 RefSeq gene 91247 91687 . + . ID=gene-NBT03_gp091;Dbxref=GeneID:72551507;Name=OPG112;gbkey=Gene;gene=OPG112;gene_biotype=protein_coding;locus_tag=NBT03_gp091;old_locus_tag=MPXV-M5312_HM12_Rivers-095 +NC_063383.1 RefSeq CDS 91247 91687 . + 0 ID=cds-YP_010377094.1;Parent=gene-NBT03_gp091;Dbxref=GenBank:YP_010377094.1,GeneID:72551507;Name=OPG112;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp097%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR H7R and VACV-Cop H7R;gbkey=CDS;gene=OPG112;locus_tag=NBT03_gp091;product=Late protein H7;protein_id=YP_010377094.1 +NC_063383.1 RefSeq gene 91731 94268 . + . ID=gene-NBT03_gp092;Dbxref=GeneID:72551508;Name=OPG113;gbkey=Gene;gene=OPG113;gene_biotype=protein_coding;locus_tag=NBT03_gp092;old_locus_tag=MPXV-M5312_HM12_Rivers-096 +NC_063383.1 RefSeq CDS 91731 94268 . + 0 ID=cds-YP_010377095.1;Parent=gene-NBT03_gp092;Dbxref=GenBank:YP_010377095.1,GeneID:72551508;Name=OPG113;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp098%3B mRNA capping enzyme%2C large subunit%3B RNA 5' triphosphatase and RNA guanylyl transferase activities%3B similar to VACV-WR E1R and VACV-Cop D1R;gbkey=CDS;gene=OPG113;locus_tag=NBT03_gp092;product=mRNA capping enzyme large subunit;protein_id=YP_010377095.1 +NC_063383.1 RefSeq gene 94227 94667 . - . ID=gene-NBT03_gp093;Dbxref=GeneID:72551509;Name=OPG114;gbkey=Gene;gene=OPG114;gene_biotype=protein_coding;locus_tag=NBT03_gp093;old_locus_tag=MPXV-M5312_HM12_Rivers-097 +NC_063383.1 RefSeq CDS 94227 94667 . - 0 ID=cds-YP_010377096.1;Parent=gene-NBT03_gp093;Dbxref=GenBank:YP_010377096.1,GeneID:72551509;Name=OPG114;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp099%3B virion core protein%3B similar to VACV-WR E2L and VACV-Cop D2L;gbkey=CDS;gene=OPG114;locus_tag=NBT03_gp093;product=Virion protein D2;protein_id=YP_010377096.1 +NC_063383.1 RefSeq gene 94660 95361 . + . ID=gene-NBT03_gp094;Dbxref=GeneID:72551510;Name=OPG115;gbkey=Gene;gene=OPG115;gene_biotype=protein_coding;locus_tag=NBT03_gp094;old_locus_tag=MPXV-M5312_HM12_Rivers-098 +NC_063383.1 RefSeq CDS 94660 95361 . + 0 ID=cds-YP_010377097.1;Parent=gene-NBT03_gp094;Dbxref=GenBank:YP_010377097.1,GeneID:72551510;Name=OPG115;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp100%3B virion core protein%3B similar to VACV-WR E3R and VACV-Cop D3R;gbkey=CDS;gene=OPG115;locus_tag=NBT03_gp094;product=Virion core protein D3;protein_id=YP_010377097.1 +NC_063383.1 RefSeq gene 95361 96017 . + . ID=gene-NBT03_gp095;Dbxref=GeneID:72551511;Name=OPG116;gbkey=Gene;gene=OPG116;gene_biotype=protein_coding;locus_tag=NBT03_gp095;old_locus_tag=MPXV-M5312_HM12_Rivers-099 +NC_063383.1 RefSeq CDS 95361 96017 . + 0 ID=cds-YP_010377098.1;Parent=gene-NBT03_gp095;Dbxref=GenBank:YP_010377098.1,GeneID:72551511;Name=OPG116;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp101%3B uracil DNA glycosylase%3B DNA polymerase processivity factor%3B similar to VACV-WR E4R and VACV-Cop D4R;gbkey=CDS;gene=OPG116;locus_tag=NBT03_gp095;product=Uracil DNA glycosylase superfamily;protein_id=YP_010377098.1 +NC_063383.1 RefSeq gene 96049 98406 . + . ID=gene-NBT03_gp096;Dbxref=GeneID:72551512;Name=OPG117;gbkey=Gene;gene=OPG117;gene_biotype=protein_coding;locus_tag=NBT03_gp096;old_locus_tag=MPXV-M5312_HM12_Rivers-100 +NC_063383.1 RefSeq CDS 96049 98406 . + 0 ID=cds-YP_010377099.1;Parent=gene-NBT03_gp096;Dbxref=GenBank:YP_010377099.1,GeneID:72551512;Name=OPG117;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp102%3B nucleic acid-independent nucleoside triphosphatase%3B NTPase%2C DNA primase%3B similar to VACV-WR E5R and VACV-Cop D5R;gbkey=CDS;gene=OPG117;locus_tag=NBT03_gp096;product=NTPase (1);protein_id=YP_010377099.1 +NC_063383.1 RefSeq gene 98446 100359 . + . ID=gene-NBT03_gp097;Dbxref=GeneID:72551513;Name=OPG118;gbkey=Gene;gene=OPG118;gene_biotype=protein_coding;locus_tag=NBT03_gp097;old_locus_tag=MPXV-M5312_HM12_Rivers-101 +NC_063383.1 RefSeq CDS 98446 100359 . + 0 ID=cds-YP_010377100.1;Parent=gene-NBT03_gp097;Dbxref=GenBank:YP_010377100.1,GeneID:72551513;Name=OPG118;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp103%3B early transcription factor%2C small subunit%2C VETF-s%3B Morphogenesis%3B similar to VACV-WR E6R and VACV-Cop D6R;gbkey=CDS;gene=OPG118;locus_tag=NBT03_gp097;product=Early transcription factor 70 kDa subunit;protein_id=YP_010377100.1 +NC_063383.1 RefSeq gene 100386 100871 . + . ID=gene-NBT03_gp098;Dbxref=GeneID:72551514;Name=OPG119;gbkey=Gene;gene=OPG119;gene_biotype=protein_coding;locus_tag=NBT03_gp098;old_locus_tag=MPXV-M5312_HM12_Rivers-102 +NC_063383.1 RefSeq CDS 100386 100871 . + 0 ID=cds-YP_010377101.1;Parent=gene-NBT03_gp098;Dbxref=GenBank:YP_010377101.1,GeneID:72551514;Name=OPG119;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp104%3B RNA polymerase%2C 18 kDa subunit (RPO18)%3B similar to VACV-WR E7R and VACV-Cop D7R;gbkey=CDS;gene=OPG119;locus_tag=NBT03_gp098;product=RNA polymerase subunit RPO18;protein_id=YP_010377101.1 +NC_063383.1 RefSeq gene 100834 101748 . - . ID=gene-NBT03_gp099;Dbxref=GeneID:72551515;Name=OPG120;gbkey=Gene;gene=OPG120;gene_biotype=protein_coding;locus_tag=NBT03_gp099;old_locus_tag=MPXV-M5312_HM12_Rivers-103 +NC_063383.1 RefSeq CDS 100834 101748 . - 0 ID=cds-YP_010377102.1;Parent=gene-NBT03_gp099;Dbxref=GenBank:YP_010377102.1,GeneID:72551515;Name=OPG120;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp105%3B IMV surface membrane 32 kDa protein%3B binding to cell surface chondroitin sulfate%3B IMV adsorption to cell surface%3B GAG-binding IMV membrane protein%3B similar to VACV-WR E8L and VACV-Cop D8L;gbkey=CDS;gene=OPG120;locus_tag=NBT03_gp099;product=Carbonic anhydrase;protein_id=YP_010377102.1 +NC_063383.1 RefSeq gene 101790 102431 . + . ID=gene-NBT03_gp100;Dbxref=GeneID:72551516;Name=OPG121;gbkey=Gene;gene=OPG121;gene_biotype=protein_coding;locus_tag=NBT03_gp100;old_locus_tag=MPXV-M5312_HM12_Rivers-104 +NC_063383.1 RefSeq CDS 101790 102431 . + 0 ID=cds-YP_010377103.1;Parent=gene-NBT03_gp100;Dbxref=GenBank:YP_010377103.1,GeneID:72551516;Name=OPG121;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp106%3B Mut-like%3B mRNA decapping enzyme%3B similar to VACV-WR E9R and VACV-Cop D9R;gbkey=CDS;gene=OPG121;locus_tag=NBT03_gp100;product=NUDIX domain protein;protein_id=YP_010377103.1 +NC_063383.1 RefSeq gene 102428 103174 . + . ID=gene-NBT03_gp101;Dbxref=GeneID:72551517;Name=OPG122;gbkey=Gene;gene=OPG122;gene_biotype=protein_coding;locus_tag=NBT03_gp101;old_locus_tag=MPXV-M5312_HM12_Rivers-105 +NC_063383.1 RefSeq CDS 102428 103174 . + 0 ID=cds-YP_010377104.1;Parent=gene-NBT03_gp101;Dbxref=GenBank:YP_010377104.1,GeneID:72551517;Name=OPG122;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp107%3B down regulation of gene expression%3B Mut-like%3B mRNA decapping enzyme%3B similar to VACV-WR E10R and VACV-Cop D10R;gbkey=CDS;gene=OPG122;locus_tag=NBT03_gp101;product=MutT motif protein;protein_id=YP_010377104.1 +NC_063383.1 RefSeq gene 103175 105070 . - . ID=gene-NBT03_gp102;Dbxref=GeneID:72551518;Name=OPG123;gbkey=Gene;gene=OPG123;gene_biotype=protein_coding;locus_tag=NBT03_gp102;old_locus_tag=MPXV-M5312_HM12_Rivers-106 +NC_063383.1 RefSeq CDS 103175 105070 . - 0 ID=cds-YP_010377105.1;Parent=gene-NBT03_gp102;Dbxref=GenBank:YP_010377105.1,GeneID:72551518;Name=OPG123;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp108%3B nucleoside triphosphate phosphohydrolase I%2C NPH I%3B DNA-dependent ATPase%3B early gene transcription termination factor%3B similar to VACV-WR E11L and VACV-Cop D11L;gbkey=CDS;gene=OPG123;locus_tag=NBT03_gp102;product=Nucleoside triphosphatase I;protein_id=YP_010377105.1 +NC_063383.1 RefSeq gene 105105 105968 . - . ID=gene-NBT03_gp103;Dbxref=GeneID:72551519;Name=OPG124;gbkey=Gene;gene=OPG124;gene_biotype=protein_coding;locus_tag=NBT03_gp103;old_locus_tag=MPXV-M5312_HM12_Rivers-107 +NC_063383.1 RefSeq CDS 105105 105968 . - 0 ID=cds-YP_010377106.1;Parent=gene-NBT03_gp103;Dbxref=GenBank:YP_010377106.1,GeneID:72551519;Name=OPG124;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp109%3B mRNA capping enzyme small subunit%3B mRNA (guanine-N7-)-methyl-transferase%3B transcription initiation factor%3B similar to VACV-WR E12L and VACV-Cop D12L;gbkey=CDS;gene=OPG124;locus_tag=NBT03_gp103;product=mRNA capping enzyme small subunit;protein_id=YP_010377106.1 +NC_063383.1 RefSeq gene 105999 107654 . - . ID=gene-NBT03_gp104;Dbxref=GeneID:72551520;Name=OPG125;gbkey=Gene;gene=OPG125;gene_biotype=protein_coding;locus_tag=NBT03_gp104;old_locus_tag=MPXV-M5312_HM12_Rivers-108 +NC_063383.1 RefSeq CDS 105999 107654 . - 0 ID=cds-YP_010377107.1;Parent=gene-NBT03_gp104;Dbxref=GenBank:YP_010377107.1,GeneID:72551520;Name=OPG125;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp110%3B protein needed for the formation of immature IMV surface membrane%3B Trimeric virion coat protein (rifampicin res)%3B similar to VACV-WR E13L and VACV-Cop D13L;gbkey=CDS;gene=OPG125;locus_tag=NBT03_gp104;product=Rifampicin resistance protein;protein_id=YP_010377107.1 +NC_063383.1 RefSeq gene 107678 108130 . - . ID=gene-NBT03_gp105;Dbxref=GeneID:72551521;Name=OPG126;gbkey=Gene;gene=OPG126;gene_biotype=protein_coding;locus_tag=NBT03_gp105;old_locus_tag=MPXV-M5312_HM12_Rivers-109 +NC_063383.1 RefSeq CDS 107678 108130 . - 0 ID=cds-YP_010377108.1;Parent=gene-NBT03_gp105;Dbxref=GenBank:YP_010377108.1,GeneID:72551521;Name=OPG126;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp111%3B late gene transcription factor%2C VLTF-2%3B similar to VACV-WR A1L and VACV-Cop A1L;gbkey=CDS;gene=OPG126;locus_tag=NBT03_gp105;product=Late transcription factor VLTF-2 (2);protein_id=YP_010377108.1 +NC_063383.1 RefSeq gene 108151 108825 . - . ID=gene-NBT03_gp106;Dbxref=GeneID:72551522;Name=OPG127;gbkey=Gene;gene=OPG127;gene_biotype=protein_coding;locus_tag=NBT03_gp106;old_locus_tag=MPXV-M5312_HM12_Rivers-110 +NC_063383.1 RefSeq CDS 108151 108825 . - 0 ID=cds-YP_010377109.1;Parent=gene-NBT03_gp106;Dbxref=GenBank:YP_010377109.1,GeneID:72551522;Name=OPG127;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp112%3B late gene transcription factor%2C VLTF-3%3B zinc binding%3B similar to VACV-WR A2L and VACV-Cop A2L;gbkey=CDS;gene=OPG127;locus_tag=NBT03_gp106;product=Late transcription factor VLTF-3 (1);protein_id=YP_010377109.1 +NC_063383.1 RefSeq gene 108822 109055 . - . ID=gene-NBT03_gp107;Dbxref=GeneID:72551523;Name=OPG128;gbkey=Gene;gene=OPG128;gene_biotype=protein_coding;locus_tag=NBT03_gp107;old_locus_tag=MPXV-M5312_HM12_Rivers-111 +NC_063383.1 RefSeq CDS 108822 109055 . - 0 ID=cds-YP_010377110.1;Parent=gene-NBT03_gp107;Dbxref=GenBank:YP_010377110.1,GeneID:72551523;Name=OPG128;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp113%3B S-S bond formation pathway protein%3B similar to VACV-WR A3L and VACV-Cop A2.5L;gbkey=CDS;gene=OPG128;locus_tag=NBT03_gp107;product=S-S bond formation pathway protein;protein_id=YP_010377110.1 +NC_063383.1 RefSeq gene 109070 111004 . - . ID=gene-NBT03_gp108;Dbxref=GeneID:72551524;Name=OPG129;gbkey=Gene;gene=OPG129;gene_biotype=protein_coding;locus_tag=NBT03_gp108;old_locus_tag=MPXV-M5312_HM12_Rivers-112 +NC_063383.1 RefSeq CDS 109070 111004 . - 0 ID=cds-YP_010377111.1;Parent=gene-NBT03_gp108;Dbxref=GenBank:YP_010377111.1,GeneID:72551524;Name=OPG129;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp114%3B major virion core protein p4b%3B P4b precursor%3B similar to VACV-WR A4L and VACV-Cop A3L;gbkey=CDS;gene=OPG129;locus_tag=NBT03_gp108;product=Virion core protein P4b;protein_id=YP_010377111.1 +NC_063383.1 RefSeq gene 111057 111902 . - . ID=gene-NBT03_gp109;Dbxref=GeneID:72551525;Name=OPG130;gbkey=Gene;gene=OPG130;gene_biotype=protein_coding;locus_tag=NBT03_gp109;old_locus_tag=MPXV-M5312_HM12_Rivers-113 +NC_063383.1 RefSeq CDS 111057 111902 . - 0 ID=cds-YP_010377112.1;Parent=gene-NBT03_gp109;Dbxref=GenBank:YP_010377112.1,GeneID:72551525;Name=OPG130;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp115%3B 39 kDa immunodominant virion core protein needed for the progression of IV to infectious IMV%3B 39kDa virion core protein%3B similar to VACV-WR A5L and VACV-Cop A4L;gbkey=CDS;gene=OPG130;locus_tag=NBT03_gp109;product=A5L protein-like;protein_id=YP_010377112.1 +NC_063383.1 RefSeq gene 111940 112425 . + . ID=gene-NBT03_gp110;Dbxref=GeneID:72551526;Name=OPG131;gbkey=Gene;gene=OPG131;gene_biotype=protein_coding;locus_tag=NBT03_gp110;old_locus_tag=MPXV-M5312_HM12_Rivers-114 +NC_063383.1 RefSeq CDS 111940 112425 . + 0 ID=cds-YP_010377113.1;Parent=gene-NBT03_gp110;Dbxref=GenBank:YP_010377113.1,GeneID:72551526;Name=OPG131;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp116%3B precursor of RNA polymerase 22 kDa and 21 kDa%3B RNA polymerase subunit (RPO19)%3B similar to VACV-WR A6R and VACV-Cop A5R;gbkey=CDS;gene=OPG131;locus_tag=NBT03_gp110;product=DNA-directed RNA polymerase 19 kDa subunit;protein_id=YP_010377113.1 +NC_063383.1 RefSeq gene 112422 113540 . - . ID=gene-NBT03_gp111;Dbxref=GeneID:72551527;Name=OPG132;gbkey=Gene;gene=OPG132;gene_biotype=protein_coding;locus_tag=NBT03_gp111;old_locus_tag=MPXV-M5312_HM12_Rivers-115 +NC_063383.1 RefSeq CDS 112422 113540 . - 0 ID=cds-YP_010377114.1;Parent=gene-NBT03_gp111;Dbxref=GenBank:YP_010377114.1,GeneID:72551527;Name=OPG132;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp117%3B Viral membrane assembly proteins (VMAP)%2C core protein%3B similar to VACV-WR A7L and VACV-Cop A6L;gbkey=CDS;gene=OPG132;locus_tag=NBT03_gp111;product=Virion morphogenesis protein;protein_id=YP_010377114.1 +NC_063383.1 RefSeq gene 113564 115696 . - . ID=gene-NBT03_gp112;Dbxref=GeneID:72551528;Name=OPG133;gbkey=Gene;gene=OPG133;gene_biotype=protein_coding;locus_tag=NBT03_gp112;old_locus_tag=MPXV-M5312_HM12_Rivers-116 +NC_063383.1 RefSeq CDS 113564 115696 . - 0 ID=cds-YP_010377115.1;Parent=gene-NBT03_gp112;Dbxref=GenBank:YP_010377115.1,GeneID:72551528;Name=OPG133;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp118%3B early transcription factor%2C large subunit%2C VETF-L%3B needed for morphogenesis of the virion core%3B similar to VACV-WR A8L and VACV-Cop A7L;gbkey=CDS;gene=OPG133;locus_tag=NBT03_gp112;product=Early transcription factor 82 kDa subunit;protein_id=YP_010377115.1 +NC_063383.1 RefSeq gene 115750 116628 . + . ID=gene-NBT03_gp113;Dbxref=GeneID:72551529;Name=OPG134;gbkey=Gene;gene=OPG134;gene_biotype=protein_coding;locus_tag=NBT03_gp113;old_locus_tag=MPXV-M5312_HM12_Rivers-117 +NC_063383.1 RefSeq CDS 115750 116628 . + 0 ID=cds-YP_010377116.1;Parent=gene-NBT03_gp113;Dbxref=GenBank:YP_010377116.1,GeneID:72551529;Name=OPG134;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp119%3B intermediate transcription factor%2C VITF-3 34kda subunit%2C 34 kDa%3B similar to VACV-WR A9R and VACV-Cop A8R;gbkey=CDS;gene=OPG134;locus_tag=NBT03_gp113;product=Intermediate transcription factor VITF-3 (1);protein_id=YP_010377116.1 +NC_063383.1 RefSeq gene 116609 116911 . - . ID=gene-NBT03_gp114;Dbxref=GeneID:72551530;Name=OPG135;gbkey=Gene;gene=OPG135;gene_biotype=protein_coding;locus_tag=NBT03_gp114;old_locus_tag=MPXV-M5312_HM12_Rivers-118 +NC_063383.1 RefSeq CDS 116609 116911 . - 0 ID=cds-YP_010377117.1;Parent=gene-NBT03_gp114;Dbxref=GenBank:YP_010377117.1,GeneID:72551530;Name=OPG135;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp120%3B Viral membrane associated%2C early morphogenesis protein%3B similar to VACV-WR A10L and VACV-Cop A9L;gbkey=CDS;gene=OPG135;locus_tag=NBT03_gp114;product=IMV membrane protein A9;protein_id=YP_010377117.1 +NC_063383.1 RefSeq gene 116912 119587 . - . ID=gene-NBT03_gp115;Dbxref=GeneID:72551531;Name=OPG136;gbkey=Gene;gene=OPG136;gene_biotype=protein_coding;locus_tag=NBT03_gp115;old_locus_tag=MPXV-M5312_HM12_Rivers-119 +NC_063383.1 RefSeq CDS 116912 119587 . - 0 ID=cds-YP_010377118.1;Parent=gene-NBT03_gp115;Dbxref=GenBank:YP_010377118.1,GeneID:72551531;Name=OPG136;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp121%3B major virion core protein p4a%3B P4a precursor%3B similar to VACV-WR A11L and VACV-Cop A10L;gbkey=CDS;gene=OPG136;locus_tag=NBT03_gp115;product=Virion core protein P4a;protein_id=YP_010377118.1 +NC_063383.1 RefSeq gene 119602 120558 . + . ID=gene-NBT03_gp116;Dbxref=GeneID:72551532;Name=OPG137;gbkey=Gene;gene=OPG137;gene_biotype=protein_coding;locus_tag=NBT03_gp116;old_locus_tag=MPXV-M5312_HM12_Rivers-120 +NC_063383.1 RefSeq CDS 119602 120558 . + 0 ID=cds-YP_010377119.1;Parent=gene-NBT03_gp116;Dbxref=GenBank:YP_010377119.1,GeneID:72551532;Name=OPG137;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp122%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR A12R and VACV-Cop A11R;gbkey=CDS;gene=OPG137;locus_tag=NBT03_gp116;product=Viral membrane formation protein;protein_id=YP_010377119.1 +NC_063383.1 RefSeq gene 120560 121132 . - . ID=gene-NBT03_gp117;Dbxref=GeneID:72551533;Name=OPG138;gbkey=Gene;gene=OPG138;gene_biotype=protein_coding;locus_tag=NBT03_gp117;old_locus_tag=MPXV-M5312_HM12_Rivers-121 +NC_063383.1 RefSeq CDS 120560 121132 . - 0 ID=cds-YP_010377120.1;Parent=gene-NBT03_gp117;Dbxref=GenBank:YP_010377120.1,GeneID:72551533;Name=OPG138;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp123%3B Virion core and cleavage processing protein%3B similar to VACV-WR A13L and VACV-Cop A12L;gbkey=CDS;gene=OPG138;locus_tag=NBT03_gp117;product=A12 protein;protein_id=YP_010377120.1 +NC_063383.1 RefSeq gene 121156 121368 . - . ID=gene-NBT03_gp118;Dbxref=GeneID:72551534;Name=OPG139;gbkey=Gene;gene=OPG139;gene_biotype=protein_coding;locus_tag=NBT03_gp118;old_locus_tag=MPXV-M5312_HM12_Rivers-122 +NC_063383.1 RefSeq CDS 121156 121368 . - 0 ID=cds-YP_010377121.1;Parent=gene-NBT03_gp118;Dbxref=GenBank:YP_010377121.1,GeneID:72551534;Name=OPG139;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp124%3B IMV inner and outer membrane protein%3B virion maturation%3B similar to VACV-WR A14L and VACV-Cop A13L;gbkey=CDS;gene=OPG139;locus_tag=NBT03_gp118;product=IMV membrane protein A13L;protein_id=YP_010377121.1 +NC_063383.1 RefSeq gene 121474 121746 . - . ID=gene-NBT03_gp119;Dbxref=GeneID:72551535;Name=OPG140;gbkey=Gene;gene=OPG140;gene_biotype=protein_coding;locus_tag=NBT03_gp119;old_locus_tag=MPXV-M5312_HM12_Rivers-123 +NC_063383.1 RefSeq CDS 121474 121746 . - 0 ID=cds-YP_010377122.1;Parent=gene-NBT03_gp119;Dbxref=GenBank:YP_010377122.1,GeneID:72551535;Name=OPG140;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp125%3B IMV inner membrane protein%3B Essential IMV membrane protein%3B similar to VACV-WR A15L and VACV-Cop A14L;gbkey=CDS;gene=OPG140;locus_tag=NBT03_gp119;product=IMV membrane protein A14;protein_id=YP_010377122.1 +NC_063383.1 RefSeq gene 121763 121924 . - . ID=gene-NBT03_gp120;Dbxref=GeneID:72551536;Name=OPG141;gbkey=Gene;gene=OPG141;gene_biotype=protein_coding;locus_tag=NBT03_gp120;old_locus_tag=MPXV-M5312_HM12_Rivers-124 +NC_063383.1 RefSeq CDS 121763 121924 . - 0 ID=cds-YP_010377123.1;Parent=gene-NBT03_gp120;Dbxref=GenBank:YP_010377123.1,GeneID:72551536;Name=OPG141;Note=Taxonomic breadth: chordopoxvirinae%3B Non-essential IMV membrane protein%3B similar to VACV-WR A15.5L and VACV-Cop A14.5L;gbkey=CDS;gene=OPG141;locus_tag=NBT03_gp120;product=DUF1029 domain protein;protein_id=YP_010377123.1 +NC_063383.1 RefSeq gene 121914 122198 . - . ID=gene-NBT03_gp121;Dbxref=GeneID:72551537;Name=OPG142;gbkey=Gene;gene=OPG142;gene_biotype=protein_coding;locus_tag=NBT03_gp121;old_locus_tag=MPXV-M5312_HM12_Rivers-125 +NC_063383.1 RefSeq CDS 121914 122198 . - 0 ID=cds-YP_010377124.1;Parent=gene-NBT03_gp121;Dbxref=GenBank:YP_010377124.1,GeneID:72551537;Name=OPG142;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp126%3B Core protein%3B similar to VACV-WR A16L and VACV-Cop A15L;gbkey=CDS;gene=OPG142;locus_tag=NBT03_gp121;product=Core protein A15;protein_id=YP_010377124.1 +NC_063383.1 RefSeq gene 122182 123315 . - . ID=gene-NBT03_gp122;Dbxref=GeneID:72551538;Name=OPG143;gbkey=Gene;gene=OPG143;gene_biotype=protein_coding;locus_tag=NBT03_gp122;old_locus_tag=MPXV-M5312_HM12_Rivers-126 +NC_063383.1 RefSeq CDS 122182 123315 . - 0 ID=cds-YP_010377125.1;Parent=gene-NBT03_gp122;Dbxref=GenBank:YP_010377125.1,GeneID:72551538;Name=OPG143;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp127%3B soluble myristylated protein%3B essential for entry/fusion%3B similar to VACV-WR A17L and VACV-Cop A16L;gbkey=CDS;gene=OPG143;locus_tag=NBT03_gp122;product=Myristylated protein;protein_id=YP_010377125.1 +NC_063383.1 RefSeq gene 123318 123932 . - . ID=gene-NBT03_gp123;Dbxref=GeneID:72551539;Name=OPG144;gbkey=Gene;gene=OPG144;gene_biotype=protein_coding;locus_tag=NBT03_gp123;old_locus_tag=MPXV-M5312_HM12_Rivers-127 +NC_063383.1 RefSeq CDS 123318 123932 . - 0 ID=cds-YP_010377126.1;Parent=gene-NBT03_gp123;Dbxref=GenBank:YP_010377126.1,GeneID:72551539;Name=OPG144;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp128%3B IMV surface membrane protein%3B early function in virion morphgenesis%3B similar to VACV-WR A18L and VACV-Cop A17L;gbkey=CDS;gene=OPG144;locus_tag=NBT03_gp123;product=IMV membrane protein P21;protein_id=YP_010377126.1 +NC_063383.1 RefSeq gene 123947 125425 . + . ID=gene-NBT03_gp124;Dbxref=GeneID:72551540;Name=OPG145;gbkey=Gene;gene=OPG145;gene_biotype=protein_coding;locus_tag=NBT03_gp124;old_locus_tag=MPXV-M5312_HM12_Rivers-128 +NC_063383.1 RefSeq CDS 123947 125425 . + 0 ID=cds-YP_010377127.1;Parent=gene-NBT03_gp124;Dbxref=GenBank:YP_010377127.1,GeneID:72551540;Name=OPG145;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp129%3B virion core associated DNA helicase%3B post-replicative negative transcription elongation factor%3B transcript release factor%3B similar to VACV-WR A19R and VACV-Cop A18R;gbkey=CDS;gene=OPG145;locus_tag=NBT03_gp124;product=DNA helicase;protein_id=YP_010377127.1 +NC_063383.1 RefSeq gene 125406 125639 . - . ID=gene-NBT03_gp125;Dbxref=GeneID:72551541;Name=OPG146;gbkey=Gene;gene=OPG146;gene_biotype=protein_coding;locus_tag=NBT03_gp125;old_locus_tag=MPXV-M5312_HM12_Rivers-129 +NC_063383.1 RefSeq CDS 125406 125639 . - 0 ID=cds-YP_010377128.1;Parent=gene-NBT03_gp125;Dbxref=GenBank:YP_010377128.1,GeneID:72551541;Name=OPG146;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp130%3B Zinc finger-like protein%3B similar to VACV-WR A20L and VACV-Cop A19L;gbkey=CDS;gene=OPG146;locus_tag=NBT03_gp125;product=Zinc finger-like protein (1);protein_id=YP_010377128.1 +NC_063383.1 RefSeq gene 125640 125987 . - . ID=gene-NBT03_gp126;Dbxref=GeneID:72551542;Name=OPG147;gbkey=Gene;gene=OPG147;gene_biotype=protein_coding;locus_tag=NBT03_gp126;old_locus_tag=MPXV-M5312_HM12_Rivers-130 +NC_063383.1 RefSeq CDS 125640 125987 . - 0 ID=cds-YP_010377129.1;Parent=gene-NBT03_gp126;Dbxref=GenBank:YP_010377129.1,GeneID:72551542;Name=OPG147;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp131%3B IMV membrane protein%2C entry/fusion complex component%3B similar to VACV-WR A21L and VACV-Cop A21L;gbkey=CDS;gene=OPG147;locus_tag=NBT03_gp126;product=IMV membrane protein A21;protein_id=YP_010377129.1 +NC_063383.1 RefSeq gene 125986 127266 . + . ID=gene-NBT03_gp127;Dbxref=GeneID:72551543;Name=OPG148;gbkey=Gene;gene=OPG148;gene_biotype=protein_coding;locus_tag=NBT03_gp127;old_locus_tag=MPXV-M5312_HM12_Rivers-131 +NC_063383.1 RefSeq CDS 125986 127266 . + 0 ID=cds-YP_010377130.1;Parent=gene-NBT03_gp127;Dbxref=GenBank:YP_010377130.1,GeneID:72551543;Name=OPG148;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp132%3B processivity factor for the viral DNA polymerase%2C VPF%3B similar to VACV-WR A22R and VACV-Cop A20R;gbkey=CDS;gene=OPG148;locus_tag=NBT03_gp127;product=DNA polymerase processivity factor;protein_id=YP_010377130.1 +NC_063383.1 RefSeq gene 127196 127759 . + . ID=gene-NBT03_gp128;Dbxref=GeneID:72551544;Name=OPG149;gbkey=Gene;gene=OPG149;gene_biotype=protein_coding;locus_tag=NBT03_gp128;old_locus_tag=MPXV-M5312_HM12_Rivers-132 +NC_063383.1 RefSeq CDS 127196 127759 . + 0 ID=cds-YP_010377131.1;Parent=gene-NBT03_gp128;Dbxref=GenBank:YP_010377131.1,GeneID:72551544;Name=OPG149;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp133%3B Holliday junction resolvase%3B similar to VACV-WR A23R and VACV-Cop A22R;gbkey=CDS;gene=OPG149;locus_tag=NBT03_gp128;product=Holliday junction resolvase;protein_id=YP_010377131.1 +NC_063383.1 RefSeq gene 127779 128927 . + . ID=gene-NBT03_gp129;Dbxref=GeneID:72551545;Name=OPG150;gbkey=Gene;gene=OPG150;gene_biotype=protein_coding;locus_tag=NBT03_gp129;old_locus_tag=MPXV-M5312_HM12_Rivers-133 +NC_063383.1 RefSeq CDS 127779 128927 . + 0 ID=cds-YP_010377132.1;Parent=gene-NBT03_gp129;Dbxref=GenBank:YP_010377132.1,GeneID:72551545;Name=OPG150;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp134%3B intermediate transcription factor%2C VITF-3%2C 45 kDa subunit%3B similar to VACV-WR A24R and VACV-Cop A23R;gbkey=CDS;gene=OPG150;locus_tag=NBT03_gp129;product=Intermediate transcription factor VITF-3 (2);protein_id=YP_010377132.1 +NC_063383.1 RefSeq gene 128924 132418 . + . ID=gene-NBT03_gp130;Dbxref=GeneID:72551546;Name=OPG151;gbkey=Gene;gene=OPG151;gene_biotype=protein_coding;locus_tag=NBT03_gp130;old_locus_tag=MPXV-M5312_HM12_Rivers-134 +NC_063383.1 RefSeq CDS 128924 132418 . + 0 ID=cds-YP_010377133.1;Parent=gene-NBT03_gp130;Dbxref=GenBank:YP_010377133.1,GeneID:72551546;Name=OPG151;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp135%3B RNA polymerase%2C 132 kDa subunit (RPO132)%3B similar to VACV-WR A25R and VACV-Cop A24R;gbkey=CDS;gene=OPG151;locus_tag=NBT03_gp130;product=DNA-dependent RNA polymerase subunit rpo132;protein_id=YP_010377133.1 +NC_063383.1 RefSeq sequence_feature 132396 136092 . - . ID=id-NC_063383.1:132396..136092;exon_number=OPG152;gbkey=misc_feature;number=OPG152 +NC_063383.1 RefSeq gene 136138 137667 . - . ID=gene-NBT03_gp131;Dbxref=GeneID:72551547;Name=OPG153;gbkey=Gene;gene=OPG153;gene_biotype=protein_coding;locus_tag=NBT03_gp131;old_locus_tag=MPXV-M5312_HM12_Rivers-137 +NC_063383.1 RefSeq CDS 136138 137667 . - 0 ID=cds-YP_010377134.1;Parent=gene-NBT03_gp131;Dbxref=GenBank:YP_010377134.1,GeneID:72551547;Name=OPG153;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp138%3B major component of IMV surface tubules%3B A-type inclusion protein%3B P4c precursor%3B similar to VACV-WR A28L and VACV-Cop A26L;gbkey=CDS;gene=OPG153;locus_tag=NBT03_gp131;product=Orthopoxvirus A26L/A30L protein;protein_id=YP_010377134.1 +NC_063383.1 RefSeq gene 137718 138050 . - . ID=gene-NBT03_gp132;Dbxref=GeneID:72551548;Name=OPG154;gbkey=Gene;gene=OPG154;gene_biotype=protein_coding;locus_tag=NBT03_gp132;old_locus_tag=MPXV-M5312_HM12_Rivers-138 +NC_063383.1 RefSeq CDS 137718 138050 . - 0 ID=cds-YP_010377135.1;Parent=gene-NBT03_gp132;Dbxref=GenBank:YP_010377135.1,GeneID:72551548;Name=OPG154;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp139%3B IMV surface membrane 14 kDa fusion protein%3B binding to cell surface heparan%3B similar to VACV-WR A29L and VACV-Cop A27L;gbkey=CDS;gene=OPG154;locus_tag=NBT03_gp132;product=IMV surface fusion protein;protein_id=YP_010377135.1 +NC_063383.1 RefSeq gene 138051 138491 . - . ID=gene-NBT03_gp133;Dbxref=GeneID:72551549;Name=OPG155;gbkey=Gene;gene=OPG155;gene_biotype=protein_coding;locus_tag=NBT03_gp133;old_locus_tag=MPXV-M5312_HM12_Rivers-139 +NC_063383.1 RefSeq CDS 138051 138491 . - 0 ID=cds-YP_010377136.1;Parent=gene-NBT03_gp133;Dbxref=GenBank:YP_010377136.1,GeneID:72551549;Name=OPG155;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp140%3B IMV MP/Virus entry%3B similar to VACV-WR A30L and VACV-Cop A28L;gbkey=CDS;gene=OPG155;locus_tag=NBT03_gp133;product=Envelope protein A28 homolog;protein_id=YP_010377136.1 +NC_063383.1 RefSeq gene 138492 139409 . - . ID=gene-NBT03_gp134;Dbxref=GeneID:72551550;Name=OPG156;gbkey=Gene;gene=OPG156;gene_biotype=protein_coding;locus_tag=NBT03_gp134;old_locus_tag=MPXV-M5312_HM12_Rivers-140 +NC_063383.1 RefSeq CDS 138492 139409 . - 0 ID=cds-YP_010377137.1;Parent=gene-NBT03_gp134;Dbxref=GenBank:YP_010377137.1,GeneID:72551550;Name=OPG156;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp141%3B RNA polymerase%2C 35 kDa subunit (RPO35)%3B similar to VACV-WR A31L and VACV-Cop A29L;gbkey=CDS;gene=OPG156;locus_tag=NBT03_gp134;product=DNA-directed RNA polymerase 35 kDa subunit;protein_id=YP_010377137.1 +NC_063383.1 RefSeq gene 139372 139608 . - . ID=gene-NBT03_gp135;Dbxref=GeneID:72551551;Name=OPG157;gbkey=Gene;gene=OPG157;gene_biotype=protein_coding;locus_tag=NBT03_gp135;old_locus_tag=MPXV-M5312_HM12_Rivers-141 +NC_063383.1 RefSeq CDS 139372 139608 . - 0 ID=cds-YP_010377138.1;Parent=gene-NBT03_gp135;Dbxref=GenBank:YP_010377138.1,GeneID:72551551;Name=OPG157;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp142%3B IMV protein%3B similar to VACV-WR A32L and VACV-Cop A30L;gbkey=CDS;gene=OPG157;locus_tag=NBT03_gp135;product=IMV membrane protein A30;protein_id=YP_010377138.1 +NC_063383.1 RefSeq gene 139641 139769 . - . ID=gene-NBT03_gp136;Dbxref=GeneID:72551552;Name=OPG158;gbkey=Gene;gene=OPG158;gene_biotype=protein_coding;locus_tag=NBT03_gp136;old_locus_tag=MPXV-M5312_HM12_Rivers-142 +NC_063383.1 RefSeq CDS 139641 139769 . - 0 ID=cds-YP_010377139.1;Parent=gene-NBT03_gp136;Dbxref=GenBank:YP_010377139.1,GeneID:72551552;Name=OPG158;Note=Viral membrane assembly proteins (VMAP)%3B similar to VACV-Cop A30.5L;gbkey=CDS;gene=OPG158;locus_tag=NBT03_gp136;product=A32.5L;protein_id=YP_010377139.1 +NC_063383.1 RefSeq gene 139768 140205 . + . ID=gene-NBT03_gp137;Dbxref=GeneID:72551553;Name=OPG159;gbkey=Gene;gene=OPG159;gene_biotype=protein_coding;locus_tag=NBT03_gp137;old_locus_tag=MPXV-M5312_HM12_Rivers-143 +NC_063383.1 RefSeq CDS 139768 140205 . + 0 ID=cds-YP_010377140.1;Parent=gene-NBT03_gp137;Dbxref=GenBank:YP_010377140.1,GeneID:72551553;Name=OPG159;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp143%3B Hypothetical protein%3B similar to VACV-WR A33R and VACV-Cop A31R;gbkey=CDS;gene=OPG159;locus_tag=NBT03_gp137;product=CPXV166 protein;protein_id=YP_010377140.1 +NC_063383.1 RefSeq gene 140172 141074 . - . ID=gene-NBT03_gp138;Dbxref=GeneID:72551554;Name=OPG160;gbkey=Gene;gene=OPG160;gene_biotype=protein_coding;locus_tag=NBT03_gp138;old_locus_tag=MPXV-M5312_HM12_Rivers-144 +NC_063383.1 RefSeq CDS 140172 141074 . - 0 ID=cds-YP_010377141.1;Parent=gene-NBT03_gp138;Dbxref=GenBank:YP_010377141.1,GeneID:72551554;Name=OPG160;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp144%3B DNA packaging into virion%3B NTP-binding motif A%3B ATPase/DNA packaging protein%3B similar to VACV-WR A34L and VACV-Cop A32L;gbkey=CDS;gene=OPG160;locus_tag=NBT03_gp138;product=ATPase A32;protein_id=YP_010377141.1 +NC_063383.1 RefSeq gene 141102 141647 . + . ID=gene-NBT03_gp139;Dbxref=GeneID:72551555;Name=OPG161;gbkey=Gene;gene=OPG161;gene_biotype=protein_coding;locus_tag=NBT03_gp139;old_locus_tag=MPXV-M5312_HM12_Rivers-145 +NC_063383.1 RefSeq CDS 141102 141647 . + 0 ID=cds-YP_010377142.1;Parent=gene-NBT03_gp139;Dbxref=GenBank:YP_010377142.1,GeneID:72551555;Name=OPG161;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp145%3B EEV envelope glycoprotein%2C needed for formation of actin-containing microvilli and cell-to-cell spread of virion%3B interacts with VAC A36R%3B EEV membrane phosphoglycoprotein%2C C-type lectin-like domain%3B similar to VACV-WR A35R and VACV-Cop A33R;gbkey=CDS;gene=OPG161;locus_tag=NBT03_gp139;product=EEV glycoprotein (1);protein_id=YP_010377142.1 +NC_063383.1 RefSeq gene 141652 142158 . + . ID=gene-NBT03_gp140;Dbxref=GeneID:72551556;Name=OPG162;gbkey=Gene;gene=OPG162;gene_biotype=protein_coding;locus_tag=NBT03_gp140;old_locus_tag=MPXV-M5312_HM12_Rivers-146 +NC_063383.1 RefSeq CDS 141652 142158 . + 0 ID=cds-YP_010377143.1;Parent=gene-NBT03_gp140;Dbxref=GenBank:YP_010377143.1,GeneID:72551556;Name=OPG162;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp146%3B EEV envelope glycoprotein%2C lectin-like%3B required for infectivity of EEV%2C formation of actin-containing microvilli%2C and cell-to-cell spread of virion%3B C-type lectin-like IEV/EEV glycoprotein%3B similar to VACV-WR A36R and VACV-Cop A34R;gbkey=CDS;gene=OPG162;locus_tag=NBT03_gp140;product=EEV glycoprotein (2);protein_id=YP_010377143.1 +NC_063383.1 RefSeq gene 142202 142732 . + . ID=gene-NBT03_gp141;Dbxref=GeneID:72551557;Name=OPG163;gbkey=Gene;gene=OPG163;gene_biotype=protein_coding;locus_tag=NBT03_gp141;old_locus_tag=MPXV-M5312_HM12_Rivers-147 +NC_063383.1 RefSeq CDS 142202 142732 . + 0 ID=cds-YP_010377144.1;Parent=gene-NBT03_gp141;Dbxref=GenBank:YP_010377144.1,GeneID:72551557;Name=OPG163;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp147%3B MHC class II antigen presentation inhibitor%3B similar to VACV-WR A37R and VACV-Cop A35R;gbkey=CDS;gene=OPG163;locus_tag=NBT03_gp141;product=MHC class II antigen presentation inhibitor;protein_id=YP_010377144.1 +NC_063383.1 RefSeq gene 142778 143464 . + . ID=gene-NBT03_gp142;Dbxref=GeneID:72551558;Name=OPG164;gbkey=Gene;gene=OPG164;gene_biotype=protein_coding;locus_tag=NBT03_gp142;old_locus_tag=MPXV-M5312_HM12_Rivers-148 +NC_063383.1 RefSeq CDS 142778 143464 . + 0 ID=cds-YP_010377145.1;Parent=gene-NBT03_gp142;Dbxref=GenBank:YP_010377145.1,GeneID:72551558;Name=OPG164;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp148%3B IEV but not CEV envelope protein%3B plays critical role for actin tail formation%3B interacts with VAC A33R and A34R%3B IEV transmembrane phosphoprotein%3B similar to VACV-WR A38R and VACV-Cop A36R;gbkey=CDS;gene=OPG164;locus_tag=NBT03_gp142;product=IEV transmembrane phosphoprotein;protein_id=YP_010377145.1 +NC_063383.1 RefSeq gene 143516 144322 . + . ID=gene-NBT03_gp143;Dbxref=GeneID:72551559;Name=OPG165;gbkey=Gene;gene=OPG165;gene_biotype=protein_coding;locus_tag=NBT03_gp143;old_locus_tag=MPXV-M5312_HM12_Rivers-149 +NC_063383.1 RefSeq CDS 143516 144322 . + 0 ID=cds-YP_010377146.1;Parent=gene-NBT03_gp143;Dbxref=GenBank:YP_010377146.1,GeneID:72551559;Name=OPG165;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp149%3B Hypothetical protein%3B similar to VACV-WR A39R and VACV-Cop A37R;gbkey=CDS;gene=OPG165;locus_tag=NBT03_gp143;product=CPXV173 protein;protein_id=YP_010377146.1 +NC_063383.1 RefSeq gene 144398 144577 . + . ID=gene-NBT03_gp144;Dbxref=GeneID:72551560;Name=OPG166;gbkey=Gene;gene=OPG166;gene_biotype=protein_coding;locus_tag=NBT03_gp144 +NC_063383.1 RefSeq CDS 144398 144577 . + 0 ID=cds-YP_010415322.1;Parent=gene-NBT03_gp144;Dbxref=GenBank:YP_010415322.1,GeneID:72551560;Name=OPG166;Note=Hypothetical protein%3B according to YP_233043.1%2C this VACV-WR protein was purified by sucrose gradient centrifugation%3B similar to VACWR161 and VARGAR-A43R;gbkey=CDS;gene=OPG166;locus_tag=NBT03_gp144;product=hypothetical protein;protein_id=YP_010415322.1 +NC_063383.1 RefSeq gene 144574 145407 . - . ID=gene-NBT03_gp145;Dbxref=GeneID:72551561;Name=OPG167;gbkey=Gene;gene=OPG167;gene_biotype=protein_coding;locus_tag=NBT03_gp145;old_locus_tag=MPXV-M5312_HM12_Rivers-150 +NC_063383.1 RefSeq CDS 144574 145407 . - 0 ID=cds-YP_010377147.1;Parent=gene-NBT03_gp145;Dbxref=GenBank:YP_010377147.1,GeneID:72551561;Name=OPG167;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp150%3B integral membrane glycoprotein%3B immunoglobulin-like%3B regulation of the influx of extracellular Ca2+%3B CD47-like%3B similar to VACV-WR A40L and VACV-Cop A38L;gbkey=CDS;gene=OPG167;locus_tag=NBT03_gp145;product=CD47-like protein;protein_id=YP_010377147.1 +NC_063383.1 RefSeq sequence_feature 145423 145856 . + . ID=id-NC_063383.1:145423..145856;exon_number=OPG168;gbkey=misc_feature;number=OPG168 +NC_063383.1 RefSeq sequence_feature 145857 146039 . + . ID=id-NC_063383.1:145857..146039;exon_number=OPG169;gbkey=misc_feature;number=OPG169 +NC_063383.1 RefSeq gene 146113 146778 . - . ID=gene-NBT03_gp146;Dbxref=GeneID:72551562;Name=OPG170;gbkey=Gene;gene=OPG170;gene_biotype=protein_coding;locus_tag=NBT03_gp146;old_locus_tag=MPXV-M5312_HM12_Rivers-151 +NC_063383.1 RefSeq CDS 146113 146778 . - 0 ID=cds-YP_010377148.1;Parent=gene-NBT03_gp146;Dbxref=GenBank:YP_010377148.1,GeneID:72551562;Name=OPG170;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp151%3B secreted protein reducing infiltration of inflammatory cells into the infected area%3B Chemokine binding protein%3B similar to VACV-WR A41L and VACV-Cop A41L;gbkey=CDS;gene=OPG170;locus_tag=NBT03_gp146;product=Chemokine binding protein;protein_id=YP_010377148.1 +NC_063383.1 RefSeq gene 146988 147389 . + . ID=gene-NBT03_gp147;Dbxref=GeneID:72551563;Name=OPG171;gbkey=Gene;gene=OPG171;gene_biotype=protein_coding;locus_tag=NBT03_gp147;old_locus_tag=MPXV-M5312_HM12_Rivers-152 +NC_063383.1 RefSeq CDS 146988 147389 . + 0 ID=cds-YP_010377149.1;Parent=gene-NBT03_gp147;Dbxref=GenBank:YP_010377149.1,GeneID:72551563;Name=OPG171;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp152%3B Profilin-like protein%2C ATI-localized%3B similar to VACV-WR A42R and VACV-Cop A42R;gbkey=CDS;gene=OPG171;locus_tag=NBT03_gp147;product=Profilin domain protein;protein_id=YP_010377149.1 +NC_063383.1 RefSeq gene 147427 148017 . + . ID=gene-NBT03_gp148;Dbxref=GeneID:72551564;Name=OPG172;gbkey=Gene;gene=OPG172;gene_biotype=protein_coding;locus_tag=NBT03_gp148;old_locus_tag=MPXV-M5312_HM12_Rivers-153 +NC_063383.1 RefSeq CDS 147427 148017 . + 0 ID=cds-YP_010377150.1;Parent=gene-NBT03_gp148;Dbxref=GenBank:YP_010377150.1,GeneID:72551564;Name=OPG172;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp153%3B Type I membrane glycoprotein%3B similar to VACV-WR A43R and VACV-Cop A43R;gbkey=CDS;gene=OPG172;locus_tag=NBT03_gp148;product=Type-I membrane glycoprotein;protein_id=YP_010377150.1 +NC_063383.1 RefSeq gene 148037 148261 . + . ID=gene-NBT03_gp149;Dbxref=GeneID:72551565;Name=OPG173;gbkey=Gene;gene=OPG173;gene_biotype=protein_coding;locus_tag=NBT03_gp149;old_locus_tag=MPXV-M5312_HM12_Rivers-154 +NC_063383.1 RefSeq CDS 148037 148261 . + 0 ID=cds-YP_010377151.1;Parent=gene-NBT03_gp149;Dbxref=GenBank:YP_010377151.1,GeneID:72551565;Name=OPG173;Note=Old product: MPXVgp154%3B Hypothetical protein%3B similar to VACV-WR A44R and VACV-Cop A43.5R;gbkey=CDS;gene=OPG173;locus_tag=NBT03_gp149;product=MPXVgp154;protein_id=YP_010377151.1 +NC_063383.1 RefSeq gene 148355 149395 . - . ID=gene-NBT03_gp150;Dbxref=GeneID:72551566;Name=OPG174;gbkey=Gene;gene=OPG174;gene_biotype=protein_coding;locus_tag=NBT03_gp150;old_locus_tag=MPXV-M5312_HM12_Rivers-155 +NC_063383.1 RefSeq CDS 148355 149395 . - 0 ID=cds-YP_010377152.1;Parent=gene-NBT03_gp150;Dbxref=GenBank:YP_010377152.1,GeneID:72551566;Name=OPG174;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp155%3B 3-b-Hydroxy-delta5-steroid dehydrogenase%3B 3 beta-hydroxysteroid dehydrogenase/delta 5->4 isomerase%3B similar to VACV-WR A45L and VACV-Cop A44L;gbkey=CDS;gene=OPG174;locus_tag=NBT03_gp150;product=Hydroxysteroid dehydrogenase;protein_id=YP_010377152.1 +NC_063383.1 RefSeq gene 149442 149819 . + . ID=gene-NBT03_gp151;Dbxref=GeneID:72551567;Name=OPG175;gbkey=Gene;gene=OPG175;gene_biotype=protein_coding;locus_tag=NBT03_gp151;old_locus_tag=MPXV-M5312_HM12_Rivers-156 +NC_063383.1 RefSeq CDS 149442 149819 . + 0 ID=cds-YP_010377153.1;Parent=gene-NBT03_gp151;Dbxref=GenBank:YP_010377153.1,GeneID:72551567;Name=OPG175;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp156%3B virion core protein%3B Inactive Cu-Zn superoxide dismutase-like virion protein%3B similar to VACV-WR A46R and VACV-Cop A45R;gbkey=CDS;gene=OPG175;locus_tag=NBT03_gp151;product=Copper/zinc superoxide dismutase;protein_id=YP_010377153.1 +NC_063383.1 RefSeq gene 149809 150531 . + . ID=gene-NBT03_gp152;Dbxref=GeneID:72551568;Name=OPG176;gbkey=Gene;gene=OPG176;gene_biotype=protein_coding;locus_tag=NBT03_gp152;old_locus_tag=MPXV-M5312_HM12_Rivers-157 +NC_063383.1 RefSeq CDS 149809 150531 . + 0 ID=cds-YP_010377154.1;Parent=gene-NBT03_gp152;Dbxref=GenBank:YP_010377154.1,GeneID:72551568;Name=OPG176;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp157%3B IL-1/TLR signaling inhibitor%3B similar to VACV-WR A47R and VACV-Cop A46R;gbkey=CDS;gene=OPG176;locus_tag=NBT03_gp152;product=Bcl-2-like protein;protein_id=YP_010377154.1 +NC_063383.1 RefSeq sequence_feature 150684 151407 . - . ID=id-NC_063383.1:150684..151407;exon_number=OPG177;gbkey=misc_feature;number=OPG177 +NC_063383.1 RefSeq gene 151509 152123 . + . ID=gene-NBT03_gp153;Dbxref=GeneID:72551569;Name=OPG178;gbkey=Gene;gene=OPG178;gene_biotype=protein_coding;locus_tag=NBT03_gp153;old_locus_tag=MPXV-M5312_HM12_Rivers-158 +NC_063383.1 RefSeq CDS 151509 152123 . + 0 ID=cds-YP_010377155.1;Parent=gene-NBT03_gp153;Dbxref=GenBank:YP_010377155.1,GeneID:72551569;Name=OPG178;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp159%3B thymidylate kinase%3B start of ORF is missing approx. 37 AA compared to CPXVs%3B similar to VACV-WR A49R and VACV-Cop A48R;gbkey=CDS;gene=OPG178;locus_tag=NBT03_gp153;product=Thymidylate kinase;protein_id=YP_010377155.1 +NC_063383.1 RefSeq sequence_feature 152172 152660 . + . ID=id-NC_063383.1:152172..152660;exon_number=OPG179;gbkey=misc_feature;number=OPG179 +NC_063383.1 RefSeq gene 152692 154371 . + . ID=gene-NBT03_gp154;Dbxref=GeneID:72551570;Name=OPG180;gbkey=Gene;gene=OPG180;gene_biotype=protein_coding;locus_tag=NBT03_gp154;old_locus_tag=MPXV-M5312_HM12_Rivers-159 +NC_063383.1 RefSeq CDS 152692 154371 . + 0 ID=cds-YP_010377156.1;Parent=gene-NBT03_gp154;Dbxref=GenBank:YP_010377156.1,GeneID:72551570;Name=OPG180;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp160%3B ATP-dependent DNA ligase%3B similar to VACV-WR A50R and VACV-Cop A50R;gbkey=CDS;gene=OPG180;locus_tag=NBT03_gp154;product=DNA ligase (2);protein_id=YP_010377156.1 +NC_063383.1 RefSeq gene 154412 155416 . + . ID=gene-NBT03_gp155;Dbxref=GeneID:72551571;Name=OPG181;gbkey=Gene;gene=OPG181;gene_biotype=protein_coding;locus_tag=NBT03_gp155;old_locus_tag=MPXV-M5312_HM12_Rivers-160 +NC_063383.1 RefSeq CDS 154412 155416 . + 0 ID=cds-YP_010377157.1;Parent=gene-NBT03_gp155;Dbxref=GenBank:YP_010377157.1,GeneID:72551571;Name=OPG181;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp161%3B Hypothetical protein%3B similar to VACV-WR A51R and VACV-Cop A51R;gbkey=CDS;gene=OPG181;locus_tag=NBT03_gp155;product=M137R;protein_id=YP_010377157.1 +NC_063383.1 RefSeq sequence_feature 155485 156037 . + . ID=id-NC_063383.1:155485..156037;exon_number=OPG182;gbkey=misc_feature;number=OPG182 +NC_063383.1 RefSeq sequence_feature 156355 156916 . + . ID=id-NC_063383.1:156355..156916;exon_number=OPG183;gbkey=misc_feature;number=OPG183 +NC_063383.1 RefSeq sequence_feature 157176 158867 . + . ID=id-NC_063383.1:157176..158867;exon_number=OPG184;gbkey=misc_feature;number=OPG184 +NC_063383.1 RefSeq gene 158917 159858 . + . ID=gene-NBT03_gp156;Dbxref=GeneID:72551572;Name=OPG185;gbkey=Gene;gene=OPG185;gene_biotype=protein_coding;locus_tag=NBT03_gp156;old_locus_tag=MPXV-M5312_HM12_Rivers-162 +NC_063383.1 RefSeq CDS 158917 159858 . + 0 ID=cds-YP_010377158.1;Parent=gene-NBT03_gp156;Dbxref=GenBank:YP_010377158.1,GeneID:72551572;Name=OPG185;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp163%3B EEV envelope and cell membrane glycoprotein hemagglutinin%3B inhibition of the ability of infected cells to fuse%3B interacts with VAC F13L%3B similar to VACV-WR B2R and VACV-Cop A56R;gbkey=CDS;gene=OPG185;locus_tag=NBT03_gp156;product=Hemagglutinin;protein_id=YP_010377158.1 +NC_063383.1 RefSeq sequence_feature 159876 160470 . + . ID=id-NC_063383.1:159876..160470;exon_number=OPG186;gbkey=misc_feature;number=OPG186 +NC_063383.1 RefSeq gene 160622 161533 . + . ID=gene-NBT03_gp157;Dbxref=GeneID:72551573;Name=OPG187;gbkey=Gene;gene=OPG187;gene_biotype=protein_coding;locus_tag=NBT03_gp157;old_locus_tag=MPXV-M5312_HM12_Rivers-163 +NC_063383.1 RefSeq CDS 160622 161533 . + 0 ID=cds-YP_010377159.1;Parent=gene-NBT03_gp157;Dbxref=GenBank:YP_010377159.1,GeneID:72551573;Name=OPG187;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp164%3B serine%3B Ser/Thr Kinase%3B similar to VACV-WR B3R and VACV-Cop B1R;gbkey=CDS;gene=OPG187;locus_tag=NBT03_gp157;product=Ser/thr kinase;protein_id=YP_010377159.1 +NC_063383.1 RefSeq gene 161596 163107 . + . ID=gene-NBT03_gp158;Dbxref=GeneID:72551574;Name=OPG188;gbkey=Gene;gene=OPG188;gene_biotype=protein_coding;locus_tag=NBT03_gp158;old_locus_tag=MPXV-M5312_HM12_Rivers-164 +NC_063383.1 RefSeq CDS 161596 163107 . + 0 ID=cds-YP_010377160.1;Parent=gene-NBT03_gp158;Dbxref=GenBank:YP_010377160.1,GeneID:72551574;Name=OPG188;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp165%3B schlafen-like%3B similar to VACV-WR B4R and VACV-Cop B2R;gbkey=CDS;gene=OPG188;locus_tag=NBT03_gp158;product=Schlafen (1);protein_id=YP_010377160.1 +NC_063383.1 RefSeq gene 163333 165018 . + . ID=gene-NBT03_gp159;Dbxref=GeneID:72551575;Name=OPG189;gbkey=Gene;gene=OPG189;gene_biotype=protein_coding;locus_tag=NBT03_gp159;old_locus_tag=MPXV-M5312_HM12_Rivers-165 +NC_063383.1 RefSeq CDS 163333 165018 . + 0 ID=cds-YP_010377161.1;Parent=gene-NBT03_gp159;Dbxref=GenBank:YP_010377161.1,GeneID:72551575;Name=OPG189;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp166%3B ankyrin-like%3B similar to VACV-WR B5R and VACV-Cop B4R;gbkey=CDS;gene=OPG189;locus_tag=NBT03_gp159;product=Ankyrin repeat protein (25);protein_id=YP_010377161.1 +NC_063383.1 RefSeq gene 165122 166075 . + . ID=gene-NBT03_gp160;Dbxref=GeneID:72551576;Name=OPG190;gbkey=Gene;gene=OPG190;gene_biotype=protein_coding;locus_tag=NBT03_gp160;old_locus_tag=MPXV-M5312_HM12_Rivers-166 +NC_063383.1 RefSeq CDS 165122 166075 . + 0 ID=cds-YP_010377162.1;Parent=gene-NBT03_gp160;Dbxref=GenBank:YP_010377162.1,GeneID:72551576;Name=OPG190;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp167%3B palmitated 42 kDa glycoprotein located both on the membranes of infected cells and on EEV envelope%3B complement control protein-like%3B EEV type-1 membrane glycoprotein%2C protective antigen%3B similar to VACV-WR B6R and VACV-Cop B5R;gbkey=CDS;gene=OPG190;locus_tag=NBT03_gp160;product=EEV type-I membrane glycoprotein;protein_id=YP_010377162.1 +NC_063383.1 RefSeq gene 166161 166667 . + . ID=gene-NBT03_gp161;Dbxref=GeneID:72551577;Name=OPG191;gbkey=Gene;gene=OPG191;gene_biotype=protein_coding;locus_tag=NBT03_gp161;old_locus_tag=MPXV-M5312_HM12_Rivers-167 +NC_063383.1 RefSeq CDS 166161 166667 . + 0 ID=cds-YP_010377163.1;Parent=gene-NBT03_gp161;Dbxref=GenBank:YP_010377163.1,GeneID:72551577;Name=OPG191;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp168%3B Ankyrin-like protein%3B similar to VACV-WR B7R and VACV-Cop B6R;gbkey=CDS;gene=OPG191;locus_tag=NBT03_gp161;product=Ankyrin-like protein (46);protein_id=YP_010377163.1 +NC_063383.1 RefSeq gene 166731 167279 . + . ID=gene-NBT03_gp162;Dbxref=GeneID:72551578;Name=OPG192;gbkey=Gene;gene=OPG192;gene_biotype=protein_coding;locus_tag=NBT03_gp162;old_locus_tag=MPXV-M5312_HM12_Rivers-168 +NC_063383.1 RefSeq CDS 166731 167279 . + 0 ID=cds-YP_010377164.1;Parent=gene-NBT03_gp162;Dbxref=GenBank:YP_010377164.1,GeneID:72551578;Name=OPG192;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp169%3B Virulence%2C ER resident%3B similar to VACV-WR B8R and VACV-Cop B7R;gbkey=CDS;gene=OPG192;locus_tag=NBT03_gp162;product=Virulence protein;protein_id=YP_010377164.1 +NC_063383.1 RefSeq gene 167334 168137 . + . ID=gene-NBT03_gp163;Dbxref=GeneID:72551579;Name=OPG193;gbkey=Gene;gene=OPG193;gene_biotype=protein_coding;locus_tag=NBT03_gp163;old_locus_tag=MPXV-M5312_HM12_Rivers-169 +NC_063383.1 RefSeq CDS 167334 168137 . + 0 ID=cds-YP_010377165.1;Parent=gene-NBT03_gp163;Dbxref=GenBank:YP_010377165.1,GeneID:72551579;Name=OPG193;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp170%3B secreted IFN-g binding protein%3B Soluble IFN-g receptor-like protein%3B similar to VACV-WR B9R and VACV-Cop B8R;gbkey=CDS;gene=OPG193;locus_tag=NBT03_gp163;product=Soluble interferon-gamma receptor-like protein;protein_id=YP_010377165.1 +NC_063383.1 RefSeq gene 168230 168895 . + . ID=gene-NBT03_gp164;Dbxref=GeneID:72551580;Name=OPG195;gbkey=Gene;gene=OPG195;gene_biotype=protein_coding;locus_tag=NBT03_gp164;old_locus_tag=MPXV-M5312_HM12_Rivers-170 +NC_063383.1 RefSeq CDS 168230 168895 . + 0 ID=cds-YP_010377166.1;Parent=gene-NBT03_gp164;Dbxref=GenBank:YP_010377166.1,GeneID:72551580;Name=OPG195;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp171%3B shope fibroma virus T4 protein-like%3B ER-localized apoptosis regulator%3B similar to VACV-WR B10R and VACV-Cop B9R;gbkey=CDS;gene=OPG195;locus_tag=NBT03_gp164;product=Intracellular viral protein;protein_id=YP_010377166.1 +NC_063383.1 RefSeq sequence_feature 169001 169642 . + . ID=id-NC_063383.1:169001..169642;exon_number=OPG196;gbkey=misc_feature;number=OPG196 +NC_063383.1 RefSeq gene 169670 169972 . + . ID=gene-NBT03_gp165;Dbxref=GeneID:72551581;Name=OPG197;gbkey=Gene;gene=OPG197;gene_biotype=protein_coding;locus_tag=NBT03_gp165;old_locus_tag=MPXV-M5312_HM12_Rivers-171 +NC_063383.1 RefSeq CDS 169670 169972 . + 0 ID=cds-YP_010377167.1;Parent=gene-NBT03_gp165;Dbxref=GenBank:YP_010377167.1,GeneID:72551581;Name=OPG197;Note=Taxonomic breadth: chordopoxvirinae%3B Hypothetical protein%3B similar to VACV-Cop-B11R;gbkey=CDS;gene=OPG197;locus_tag=NBT03_gp165;product=CPXV205 protein;protein_id=YP_010377167.1 +NC_063383.1 RefSeq gene 170038 170886 . + . ID=gene-NBT03_gp166;Dbxref=GeneID:72551582;Name=OPG198;gbkey=Gene;gene=OPG198;gene_biotype=protein_coding;locus_tag=NBT03_gp166;old_locus_tag=MPXV-M5312_HM12_Rivers-172 +NC_063383.1 RefSeq CDS 170038 170886 . + 0 ID=cds-YP_010377168.1;Parent=gene-NBT03_gp166;Dbxref=GenBank:YP_010377168.1,GeneID:72551582;Name=OPG198;Note=Taxonomic breadth: poxviridae%3B protein kinase-like%3B similar to VACV-WR B11R and VACV-Cop B12R;gbkey=CDS;gene=OPG198;locus_tag=NBT03_gp166;product=Ser/thr kinase;protein_id=YP_010377168.1 +NC_063383.1 RefSeq gene 170988 172022 . + . ID=gene-NBT03_gp167;Dbxref=GeneID:72551583;Name=OPG199;gbkey=Gene;gene=OPG199;gene_biotype=protein_coding;locus_tag=NBT03_gp167;old_locus_tag=MPXV-M5312_HM12_Rivers-173 +NC_063383.1 RefSeq CDS 170988 172022 . + 0 ID=cds-YP_010377169.1;Parent=gene-NBT03_gp167;Dbxref=GenBank:YP_010377169.1,GeneID:72551583;Name=OPG199;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp173%3B serine protease inhibitor-like%2C SPI-2%3B inhibition of the IL-1b converting enzyme%3B apoptosis inhibition%3B Serpin 1%2C2%2C3%3B similar to VACV-WR B12R and VACV-Cop K2L;gbkey=CDS;gene=OPG199;locus_tag=NBT03_gp167;product=Serpin;protein_id=YP_010377169.1 +NC_063383.1 RefSeq gene 172150 172599 . + . ID=gene-NBT03_gp168;Dbxref=GeneID:72551584;Name=OPG200;gbkey=Gene;gene=OPG200;gene_biotype=protein_coding;locus_tag=NBT03_gp168;old_locus_tag=MPXV-M5312_HM12_Rivers-174 +NC_063383.1 RefSeq CDS 172150 172599 . + 0 ID=cds-YP_010377170.1;Parent=gene-NBT03_gp168;Dbxref=GenBank:YP_010377170.1,GeneID:72551584;Name=OPG200;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp174%3B Hypothetical protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR B13R and VACV-Cop C16L and B15R;gbkey=CDS;gene=OPG200;locus_tag=NBT03_gp168;product=Bcl-2-like protein;protein_id=YP_010377170.1 +NC_063383.1 RefSeq sequence_feature 172685 173697 . + . ID=id-NC_063383.1:172685..173697;exon_number=OPG201;gbkey=misc_feature;number=OPG201 +NC_063383.1 RefSeq sequence_feature 173744 174187 . - . ID=id-NC_063383.1:173744..174187;exon_number=OPG202;gbkey=misc_feature;number=OPG202 +NC_063383.1 RefSeq sequence_feature 174328 174456 . + . ID=id-NC_063383.1:174328..174456;exon_number=OPG203;gbkey=misc_feature;number=OPG203 +NC_063383.1 RefSeq gene 174532 175587 . + . ID=gene-NBT03_gp169;Dbxref=GeneID:72551585;Name=OPG204;gbkey=Gene;gene=OPG204;gene_biotype=protein_coding;locus_tag=NBT03_gp169;old_locus_tag=MPXV-M5312_HM12_Rivers-177 +NC_063383.1 RefSeq CDS 174532 175587 . + 0 ID=cds-YP_010377172.1;Parent=gene-NBT03_gp169;Dbxref=GenBank:YP_010377172.1,GeneID:72551585;Name=OPG204;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp177%3B cell surface antigen and secreted IFN-a%3B IFN-alpha/beta receptor glycoprotein%3B similar to VACV-WR B16R and VACV-Cop B19R;gbkey=CDS;gene=OPG204;locus_tag=NBT03_gp169;product=IFN-alpha/beta-receptor-like secreted glycoprotein;protein_id=YP_010377172.1 +NC_063383.1 RefSeq gene 175656 178019 . + . ID=gene-NBT03_gp170;Dbxref=GeneID:72551586;Name=OPG205;gbkey=Gene;gene=OPG205;gene_biotype=protein_coding;locus_tag=NBT03_gp170;old_locus_tag=MPXV-M5312_HM12_Rivers-178 +NC_063383.1 RefSeq CDS 175656 178019 . + 0 ID=cds-YP_010377173.1;Parent=gene-NBT03_gp170;Dbxref=GenBank:YP_010377173.1,GeneID:72551586;Name=OPG205;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp178%3B ankyrin-like%3B similar to VACV-WR B17R and VACV-Cop B20R;gbkey=CDS;gene=OPG205;locus_tag=NBT03_gp170;product=Ankyrin repeat protein (44);protein_id=YP_010377173.1 +NC_063383.1 RefSeq sequence_feature 178118 178916 . + . ID=id-NC_063383.1:178118..178916;exon_number=OPG206;gbkey=misc_feature;number=OPG206 +NC_063383.1 RefSeq gene 179266 180339 . + . ID=gene-NBT03_gp171;Dbxref=GeneID:72551587;Name=OPG208;gbkey=Gene;gene=OPG208;gene_biotype=protein_coding;locus_tag=NBT03_gp171;old_locus_tag=MPXV-M5312_HM12_Rivers-180 +NC_063383.1 RefSeq CDS 179266 180339 . + 0 ID=cds-YP_010377174.1;Parent=gene-NBT03_gp171;Dbxref=GenBank:YP_010377174.1,GeneID:72551587;Name=OPG208;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp180%3B serine protease inhibitor-like%2C SPI-1%3B apoptosis inhibition%3B Serpin 1%2C2%2C3%3B Actual start may be at position 179%2C074%3B annotated start of ORF is missing approx. 17 AA compared to CPXVs%3B similar to VACV-WR B19R and VACV-Cop K2L;gbkey=CDS;gene=OPG208;locus_tag=NBT03_gp171;product=Serpin;protein_id=YP_010377174.1 +NC_063383.1 RefSeq gene 180518 181090 . + . ID=gene-NBT03_gp172;Dbxref=GeneID:72551588;Name=OPG209;gbkey=Gene;gene=OPG209;gene_biotype=protein_coding;locus_tag=NBT03_gp172;old_locus_tag=MPXV-M5312_HM12_Rivers-181 +NC_063383.1 RefSeq CDS 180518 181090 . + 0 ID=cds-YP_010377175.1;Parent=gene-NBT03_gp172;Dbxref=GenBank:YP_010377175.1,GeneID:72551588;Name=OPG209;Note=Old product: MPXVgp181%3B Hypothetical protein%3B similar to VACV-WR B20R and VACV-Cop C14L;gbkey=CDS;gene=OPG209;locus_tag=NBT03_gp172;product=Virulence protein;protein_id=YP_010377175.1 +NC_063383.1 RefSeq gene 181356 186998 . + . ID=gene-NBT03_gp173;Dbxref=GeneID:72551589;Name=OPG210;gbkey=Gene;gene=OPG210;gene_biotype=protein_coding;locus_tag=NBT03_gp173;old_locus_tag=MPXV-M5312_HM12_Rivers-182 +NC_063383.1 RefSeq CDS 181356 186998 . + 0 ID=cds-YP_010377176.1;Parent=gene-NBT03_gp173;Dbxref=GenBank:YP_010377176.1,GeneID:72551589;Name=OPG210;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp182%3B Surface glycoprotein%3B putative membrane-associated glycoprotein%3B cadherin-like domain%3B similar to VACV-WR B21R;gbkey=CDS;gene=OPG210;locus_tag=NBT03_gp173;product=B22R family protein;protein_id=YP_010377176.1 +NC_063383.1 RefSeq sequence_feature 187317 187743 . + . ID=id-NC_063383.1:187317..187743;exon_number=OPG212;gbkey=misc_feature;number=OPG212 +NC_063383.1 RefSeq sequence_feature 187822 188298 . + . ID=id-NC_063383.1:187822..188298;exon_number=OPG213;gbkey=misc_feature;number=OPG213 +NC_063383.1 RefSeq sequence_feature 188458 188963 . + . ID=id-NC_063383.1:188458..188963;exon_number=OPG214;gbkey=misc_feature;number=OPG214 +NC_063383.1 RefSeq gene 189199 189660 . + . ID=gene-NBT03_gp174;Dbxref=GeneID:72551590;Name=OPG005;gbkey=Gene;gene=OPG005;gene_biotype=protein_coding;locus_tag=NBT03_gp174;old_locus_tag=MPXV-M5312_HM12_Rivers-184 +NC_063383.1 RefSeq CDS 189199 189660 . + 0 ID=cds-YP_010377177.1;Parent=gene-NBT03_gp174;Dbxref=GenBank:YP_010377177.1,GeneID:72551590;Name=OPG005;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp185%3B VAC B15R-like%3B Hypothetical protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR N1R and VACV-Cop C16L and B22R;gbkey=CDS;gene=OPG005;locus_tag=NBT03_gp174;product=Bcl-2-like protein;protein_id=YP_010377177.1 +NC_063383.1 RefSeq gene 190410 190940 . + . ID=gene-NBT03_gp175;Dbxref=GeneID:72551591;Name=OPG016;gbkey=Gene;gene=OPG016;gene_biotype=protein_coding;locus_tag=NBT03_gp175;old_locus_tag=MPXV-M5312_HM12_Rivers-186 +NC_063383.1 RefSeq CDS 190410 190940 . + 0 ID=cds-YP_010377184.1;Parent=gene-NBT03_gp175;Dbxref=GenBank:YP_010377184.1,GeneID:72551591;Name=OPG016;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp187%3B similar to VACV-WR N3R;gbkey=CDS;gene=OPG016;locus_tag=NBT03_gp175;product=Brix domain protein;protein_id=YP_010377184.1 +NC_063383.1 RefSeq long_terminal_repeat 190788 197209 . + . ID=id-NC_063383.1:190788..197209;gbkey=repeat_region;rpt_type=long_terminal_repeat +NC_063383.1 RefSeq gene 191054 192367 . + . ID=gene-NBT03_gp176;Dbxref=GeneID:72551592;Name=OPG015_dup;gbkey=Gene;gene=OPG015_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp176;old_locus_tag=MPXV-M5312_HM12_Rivers-187 +NC_063383.1 RefSeq CDS 191054 192367 . + 0 ID=cds-YP_010377179.1;Parent=gene-NBT03_gp176;Dbxref=GenBank:YP_010377179.1,GeneID:72551592;Name=OPG015_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp188%3B ankyrin-like%3B Ankyrin (CPXV-017)%3B similar to VACV-WR N4R;gbkey=CDS;gene=OPG015_dup;locus_tag=NBT03_gp176;product=Ankyrin repeat protein (39);protein_id=YP_010377179.1 +NC_063383.1 RefSeq gene 192603 194369 . + . ID=gene-NBT03_gp177;Dbxref=GeneID:72551593;Name=OPG003_dup;gbkey=Gene;gene=OPG003_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp177;old_locus_tag=MPXV-M5312_HM12_Rivers-188 +NC_063383.1 RefSeq CDS 192603 194369 . + 0 ID=cds-YP_010377180.1;Parent=gene-NBT03_gp177;Dbxref=GenBank:YP_010377180.1,GeneID:72551593;Name=OPG003_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp189%3B ankyrin-like%3B similar to VACV-WR J1R and VACV-Cop C19L;gbkey=CDS;gene=OPG003_dup;locus_tag=NBT03_gp177;product=Ankyrin repeat protein (25);protein_id=YP_010377180.1 +NC_063383.1 RefSeq gene 194459 195508 . + . ID=gene-NBT03_gp178;Dbxref=GeneID:72551594;Name=OPG002_dup;gbkey=Gene;gene=OPG002_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp178;old_locus_tag=MPXV-M5312_HM12_Rivers-189 +NC_063383.1 RefSeq CDS 194459 195508 . + 0 ID=cds-YP_010377181.1;Parent=gene-NBT03_gp178;Dbxref=GenBank:YP_010377181.1,GeneID:72551594;Name=OPG002_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp190%3B secreted TNF binding protein%3B TNF receptor (CrmB)%3B similar to VACV-WR J2R and VACV-Cop C22L;gbkey=CDS;gene=OPG002_dup;locus_tag=NBT03_gp178;product=Crm-B secreted TNF-alpha-receptor-like protein;protein_id=YP_010377181.1 +NC_063383.1 RefSeq gene 195635 196375 . + . ID=gene-NBT03_gp179;Dbxref=GeneID:72551595;Name=OPG001_dup;gbkey=Gene;gene=OPG001_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp179;old_locus_tag=MPXV-M5312_HM12_Rivers-190 +NC_063383.1 RefSeq CDS 195635 196375 . + 0 ID=cds-YP_010377182.1;Parent=gene-NBT03_gp179;Dbxref=GenBank:YP_010377182.1,GeneID:72551595;Name=OPG001_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp191%3B Chemokine binding protein (Cop-C23L)%3B most abundant secreted protein%3B CC-chemokine binding protein%3B similar to VACV-WR J3R and VACV-Cop C23L and B29R;gbkey=CDS;gene=OPG001_dup;locus_tag=NBT03_gp179;product=Chemokine binding protein;protein_id=YP_010377182.1 diff --git a/data/nextstrain/mpox/clade-iib/pathogen.json b/data/nextstrain/mpox/clade-iib/pathogen.json new file mode 100644 index 00000000..934126a1 --- /dev/null +++ b/data/nextstrain/mpox/clade-iib/pathogen.json @@ -0,0 +1,92 @@ +{ + "alignmentParams": { + "allowedMismatches": 5, + "excessBandwidth": 40, + "gapAlignmentSide": "left", + "minSeedCover": 0.1, + "terminalBandwidth": 200, + "windowSize": 30 + }, + "attributes": { + "name": "Mpox virus (Clade IIb)", + "reference accession": "NC_063383.1", + "reference name": "MPXV-M5312_HM12_Rivers" + }, + "compatibility": { + "cli": "3.0.0-alpha.0", + "web": "3.0.0-alpha.0" + }, + "deprecated": false, + "enabled": true, + "experimental": false, + "files": { + "changelog": "CHANGELOG.md", + "examples": "sequences.fasta", + "genomeAnnotation": "genome_annotation.gff3", + "pathogenJson": "pathogen.json", + "readme": "README.md", + "reference": "reference.fasta", + "treeJson": "tree.json" + }, + "official": true, + "qc": { + "frameShifts": { + "enabled": true, + "ignoredFrameShifts": [ + { + "codonRange": { + "begin": 289, + "end": 346 + }, + "geneName": "OPG174" + } + ], + "scoreWeight": 20 + }, + "missingData": { + "enabled": true, + "missingDataThreshold": 20000, + "scoreBias": 1000 + }, + "mixedSites": { + "enabled": true, + "mixedSitesThreshold": 40 + }, + "privateMutations": { + "cutoff": 50, + "enabled": true, + "typical": 5, + "weightLabeledSubstitutions": 6, + "weightReversionSubstitutions": 6, + "weightUnlabeledSubstitutions": 1 + }, + "snpClusters": { + "clusterCutOff": 5, + "enabled": true, + "scoreWeight": 20, + "windowSize": 100 + }, + "stopCodons": { + "enabled": true, + "ignoredStopCodons": [ + { + "codon": 187, + "geneName": "OPG015_dup" + }, + { + "codon": 187, + "geneName": "OPG015" + }, + { + "codon": 21, + "geneName": "OPG176" + } + ], + "scoreWeight": 40 + } + }, + "schemaVersion": "3.0.0", + "version": { + "tag": "unreleased" + } +} diff --git a/data/nextstrain/mpox/clade-iib/reference.fasta b/data/nextstrain/mpox/clade-iib/reference.fasta new file mode 100644 index 00000000..0f1d13ac --- /dev/null +++ b/data/nextstrain/mpox/clade-iib/reference.fasta @@ -0,0 +1,2 @@ +>NC_063383.1 Monkeypox virus, complete genome +ATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTAACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATTTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAAACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACAAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTTGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAAT diff --git a/data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/sequences.fasta b/data/nextstrain/mpox/clade-iib/sequences.fasta similarity index 100% rename from data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/sequences.fasta rename to data/nextstrain/mpox/clade-iib/sequences.fasta diff --git a/data/nextstrain/mpox/clade-iib/tree.json b/data/nextstrain/mpox/clade-iib/tree.json new file mode 100644 index 00000000..0efffd32 --- /dev/null +++ b/data/nextstrain/mpox/clade-iib/tree.json @@ -0,0 +1 @@ +{"version":"v2","meta":{"title":"Nextclade reference tree for Mpox virus (Clade IIb)","updated":"2023-11-21","build_url":"https://github.com/nextstrain/mpox/nextclade","data_provenance":[{"name":"GenBank","url":"https://www.ncbi.nlm.nih.gov/genbank/"}],"maintainers":[{"name":"Cornelius Roemer","url":"https://neherlab.org"},{"name":"Richard Neher","url":"https://neherlab.org"},{"name":"Nextstrain team","url":"https://nextstrain.org"}],"display_defaults":{"color_by":"lineage","map_triplicate":false,"distance_measure":"div","tip_label":"strain_display","transmission_lines":false},"genome_annotations":{"OPG001":{"end":1575,"seqid":"resources/genome_annotation.gff3","start":835,"strand":"-","type":"gene"},"OPG001_dup":{"end":196375,"seqid":"resources/genome_annotation.gff3","start":195635,"strand":"+","type":"gene"},"OPG002":{"end":2751,"seqid":"resources/genome_annotation.gff3","start":1702,"strand":"-","type":"gene"},"OPG002_dup":{"end":195508,"seqid":"resources/genome_annotation.gff3","start":194459,"strand":"+","type":"gene"},"OPG003":{"end":4607,"seqid":"resources/genome_annotation.gff3","start":2841,"strand":"-","type":"gene"},"OPG003_dup":{"end":194369,"seqid":"resources/genome_annotation.gff3","start":192603,"strand":"+","type":"gene"},"OPG005":{"end":189660,"seqid":"resources/genome_annotation.gff3","start":189199,"strand":"+","type":"gene"},"OPG015":{"end":6156,"seqid":"resources/genome_annotation.gff3","start":4843,"strand":"-","type":"gene"},"OPG015_dup":{"end":192367,"seqid":"resources/genome_annotation.gff3","start":191054,"strand":"+","type":"gene"},"OPG016":{"end":190940,"seqid":"resources/genome_annotation.gff3","start":190410,"strand":"+","type":"gene"},"OPG019":{"end":8008,"seqid":"resources/genome_annotation.gff3","start":7580,"strand":"+","type":"gene"},"OPG021":{"end":10315,"seqid":"resources/genome_annotation.gff3","start":9587,"strand":"+","type":"gene"},"OPG022":{"end":10858,"seqid":"resources/genome_annotation.gff3","start":10478,"strand":"-","type":"gene"},"OPG023":{"end":12900,"seqid":"resources/genome_annotation.gff3","start":10918,"strand":"-","type":"gene"},"OPG024":{"end":13228,"seqid":"resources/genome_annotation.gff3","start":13034,"strand":"-","type":"gene"},"OPG025":{"end":15267,"seqid":"resources/genome_annotation.gff3","start":13375,"strand":"-","type":"gene"},"OPG027":{"end":16377,"seqid":"resources/genome_annotation.gff3","start":15925,"strand":"-","type":"gene"},"OPG029":{"end":17069,"seqid":"resources/genome_annotation.gff3","start":16602,"strand":"-","type":"gene"},"OPG030":{"end":17833,"seqid":"resources/genome_annotation.gff3","start":17213,"strand":"-","type":"gene"},"OPG031":{"end":18828,"seqid":"resources/genome_annotation.gff3","start":17878,"strand":"-","type":"gene"},"OPG034":{"end":20005,"seqid":"resources/genome_annotation.gff3","start":19361,"strand":"-","type":"gene"},"OPG035":{"end":20404,"seqid":"resources/genome_annotation.gff3","start":20051,"strand":"-","type":"gene"},"OPG036":{"end":21064,"seqid":"resources/genome_annotation.gff3","start":20531,"strand":"-","type":"gene"},"OPG037":{"end":22433,"seqid":"resources/genome_annotation.gff3","start":21105,"strand":"-","type":"gene"},"OPG038":{"end":23159,"seqid":"resources/genome_annotation.gff3","start":22497,"strand":"-","type":"gene"},"OPG039":{"end":24118,"seqid":"resources/genome_annotation.gff3","start":23264,"strand":"-","type":"gene"},"OPG040":{"end":25478,"seqid":"resources/genome_annotation.gff3","start":24351,"strand":"-","type":"gene"},"OPG042":{"end":27097,"seqid":"resources/genome_annotation.gff3","start":25823,"strand":"-","type":"gene"},"OPG043":{"end":27955,"seqid":"resources/genome_annotation.gff3","start":27125,"strand":"-","type":"gene"},"OPG044":{"end":28540,"seqid":"resources/genome_annotation.gff3","start":28091,"strand":"+","type":"gene"},"OPG045":{"end":29262,"seqid":"resources/genome_annotation.gff3","start":28603,"strand":"-","type":"gene"},"OPG046":{"end":29729,"seqid":"resources/genome_annotation.gff3","start":29274,"strand":"-","type":"gene"},"OPG047":{"end":31194,"seqid":"resources/genome_annotation.gff3","start":29746,"strand":"-","type":"gene"},"OPG048":{"end":32164,"seqid":"resources/genome_annotation.gff3","start":31205,"strand":"-","type":"gene"},"OPG049":{"end":33151,"seqid":"resources/genome_annotation.gff3","start":32195,"strand":"-","type":"gene"},"OPG050":{"end":33408,"seqid":"resources/genome_annotation.gff3","start":33181,"strand":"-","type":"gene"},"OPG051":{"end":33649,"seqid":"resources/genome_annotation.gff3","start":33425,"strand":"-","type":"gene"},"OPG052":{"end":33995,"seqid":"resources/genome_annotation.gff3","start":33801,"strand":"-","type":"gene"},"OPG053":{"end":34690,"seqid":"resources/genome_annotation.gff3","start":34052,"strand":"-","type":"gene"},"OPG054":{"end":35996,"seqid":"resources/genome_annotation.gff3","start":34677,"strand":"-","type":"gene"},"OPG055":{"end":37083,"seqid":"resources/genome_annotation.gff3","start":36019,"strand":"-","type":"gene"},"OPG056":{"end":39034,"seqid":"resources/genome_annotation.gff3","start":37127,"strand":"-","type":"gene"},"OPG057":{"end":40195,"seqid":"resources/genome_annotation.gff3","start":39077,"strand":"-","type":"gene"},"OPG058":{"end":40434,"seqid":"resources/genome_annotation.gff3","start":40213,"strand":"-","type":"gene"},"OPG059":{"end":40633,"seqid":"resources/genome_annotation.gff3","start":40484,"strand":"-","type":"gene"},"OPG060":{"end":41182,"seqid":"resources/genome_annotation.gff3","start":40706,"strand":"-","type":"gene"},"OPG061":{"end":41884,"seqid":"resources/genome_annotation.gff3","start":41189,"strand":"-","type":"gene"},"OPG062":{"end":42252,"seqid":"resources/genome_annotation.gff3","start":41947,"strand":"+","type":"gene"},"OPG063":{"end":43688,"seqid":"resources/genome_annotation.gff3","start":42249,"strand":"-","type":"gene"},"OPG064":{"end":45898,"seqid":"resources/genome_annotation.gff3","start":43685,"strand":"-","type":"gene"},"OPG065":{"end":46483,"seqid":"resources/genome_annotation.gff3","start":46022,"strand":"-","type":"gene"},"OPG066":{"end":47428,"seqid":"resources/genome_annotation.gff3","start":46649,"strand":"-","type":"gene"},"OPG068":{"end":49904,"seqid":"resources/genome_annotation.gff3","start":48201,"strand":"+","type":"gene"},"OPG069":{"end":50486,"seqid":"resources/genome_annotation.gff3","start":49986,"strand":"+","type":"gene"},"OPG070":{"end":51411,"seqid":"resources/genome_annotation.gff3","start":50590,"strand":"+","type":"gene"},"OPG071":{"end":54438,"seqid":"resources/genome_annotation.gff3","start":51418,"strand":"-","type":"gene"},"OPG072":{"end":54757,"seqid":"resources/genome_annotation.gff3","start":54470,"strand":"+","type":"gene"},"OPG073":{"end":55141,"seqid":"resources/genome_annotation.gff3","start":54752,"strand":"-","type":"gene"},"OPG074":{"end":57125,"seqid":"resources/genome_annotation.gff3","start":55128,"strand":"-","type":"gene"},"OPG075":{"end":57498,"seqid":"resources/genome_annotation.gff3","start":57172,"strand":"-","type":"gene"},"OPG076":{"end":57630,"seqid":"resources/genome_annotation.gff3","start":57523,"strand":"-","type":"gene"},"OPG077":{"end":58583,"seqid":"resources/genome_annotation.gff3","start":57645,"strand":"-","type":"gene"},"OPG078":{"end":58811,"seqid":"resources/genome_annotation.gff3","start":58590,"strand":"-","type":"gene"},"OPG079":{"end":59621,"seqid":"resources/genome_annotation.gff3","start":58812,"strand":"-","type":"gene"},"OPG080":{"end":62018,"seqid":"resources/genome_annotation.gff3","start":59703,"strand":"-","type":"gene"},"OPG081":{"end":62285,"seqid":"resources/genome_annotation.gff3","start":62046,"strand":"-","type":"gene"},"OPG082":{"end":63452,"seqid":"resources/genome_annotation.gff3","start":62304,"strand":"-","type":"gene"},"OPG083":{"end":64716,"seqid":"resources/genome_annotation.gff3","start":63445,"strand":"-","type":"gene"},"OPG084":{"end":66752,"seqid":"resources/genome_annotation.gff3","start":64722,"strand":"+","type":"gene"},"OPG085":{"end":68531,"seqid":"resources/genome_annotation.gff3","start":66756,"strand":"-","type":"gene"},"OPG086":{"end":68863,"seqid":"resources/genome_annotation.gff3","start":68528,"strand":"-","type":"gene"},"OPG087":{"end":69519,"seqid":"resources/genome_annotation.gff3","start":68857,"strand":"+","type":"gene"},"OPG088":{"end":69863,"seqid":"resources/genome_annotation.gff3","start":69489,"strand":"-","type":"gene"},"OPG089":{"end":71170,"seqid":"resources/genome_annotation.gff3","start":69866,"strand":"+","type":"gene"},"OPG090":{"end":71370,"seqid":"resources/genome_annotation.gff3","start":71179,"strand":"+","type":"gene"},"OPG091":{"end":71867,"seqid":"resources/genome_annotation.gff3","start":71370,"strand":"+","type":"gene"},"OPG092":{"end":72947,"seqid":"resources/genome_annotation.gff3","start":71832,"strand":"-","type":"gene"},"OPG093":{"end":73760,"seqid":"resources/genome_annotation.gff3","start":72978,"strand":"+","type":"gene"},"OPG094":{"end":74802,"seqid":"resources/genome_annotation.gff3","start":73780,"strand":"+","type":"gene"},"OPG095":{"end":75555,"seqid":"resources/genome_annotation.gff3","start":74803,"strand":"+","type":"gene"},"OPG096":{"end":75865,"seqid":"resources/genome_annotation.gff3","start":75587,"strand":"+","type":"gene"},"OPG097":{"end":76875,"seqid":"resources/genome_annotation.gff3","start":75841,"strand":"-","type":"gene"},"OPG098":{"end":77655,"seqid":"resources/genome_annotation.gff3","start":76900,"strand":"+","type":"gene"},"OPG099":{"end":78051,"seqid":"resources/genome_annotation.gff3","start":77665,"strand":"+","type":"gene"},"OPG100":{"end":78466,"seqid":"resources/genome_annotation.gff3","start":78008,"strand":"+","type":"gene"},"OPG101":{"end":79019,"seqid":"resources/genome_annotation.gff3","start":78486,"strand":"+","type":"gene"},"OPG102":{"end":80086,"seqid":"resources/genome_annotation.gff3","start":79085,"strand":"+","type":"gene"},"OPG103":{"end":80558,"seqid":"resources/genome_annotation.gff3","start":80001,"strand":"+","type":"gene"},"OPG104":{"end":81019,"seqid":"resources/genome_annotation.gff3","start":80618,"strand":"-","type":"gene"},"OPG105":{"end":84986,"seqid":"resources/genome_annotation.gff3","start":81126,"strand":"+","type":"gene"},"OPG106":{"end":85498,"seqid":"resources/genome_annotation.gff3","start":84983,"strand":"-","type":"gene"},"OPG107":{"end":86081,"seqid":"resources/genome_annotation.gff3","start":85512,"strand":"+","type":"gene"},"OPG108":{"end":87059,"seqid":"resources/genome_annotation.gff3","start":86085,"strand":"-","type":"gene"},"OPG109":{"end":89447,"seqid":"resources/genome_annotation.gff3","start":87060,"strand":"-","type":"gene"},"OPG110":{"end":90264,"seqid":"resources/genome_annotation.gff3","start":89632,"strand":"+","type":"gene"},"OPG111":{"end":91209,"seqid":"resources/genome_annotation.gff3","start":90265,"strand":"+","type":"gene"},"OPG112":{"end":91687,"seqid":"resources/genome_annotation.gff3","start":91247,"strand":"+","type":"gene"},"OPG113":{"end":94268,"seqid":"resources/genome_annotation.gff3","start":91731,"strand":"+","type":"gene"},"OPG114":{"end":94667,"seqid":"resources/genome_annotation.gff3","start":94227,"strand":"-","type":"gene"},"OPG115":{"end":95361,"seqid":"resources/genome_annotation.gff3","start":94660,"strand":"+","type":"gene"},"OPG116":{"end":96017,"seqid":"resources/genome_annotation.gff3","start":95361,"strand":"+","type":"gene"},"OPG117":{"end":98406,"seqid":"resources/genome_annotation.gff3","start":96049,"strand":"+","type":"gene"},"OPG118":{"end":100359,"seqid":"resources/genome_annotation.gff3","start":98446,"strand":"+","type":"gene"},"OPG119":{"end":100871,"seqid":"resources/genome_annotation.gff3","start":100386,"strand":"+","type":"gene"},"OPG120":{"end":101748,"seqid":"resources/genome_annotation.gff3","start":100834,"strand":"-","type":"gene"},"OPG121":{"end":102431,"seqid":"resources/genome_annotation.gff3","start":101790,"strand":"+","type":"gene"},"OPG122":{"end":103174,"seqid":"resources/genome_annotation.gff3","start":102428,"strand":"+","type":"gene"},"OPG123":{"end":105070,"seqid":"resources/genome_annotation.gff3","start":103175,"strand":"-","type":"gene"},"OPG124":{"end":105968,"seqid":"resources/genome_annotation.gff3","start":105105,"strand":"-","type":"gene"},"OPG125":{"end":107654,"seqid":"resources/genome_annotation.gff3","start":105999,"strand":"-","type":"gene"},"OPG126":{"end":108130,"seqid":"resources/genome_annotation.gff3","start":107678,"strand":"-","type":"gene"},"OPG127":{"end":108825,"seqid":"resources/genome_annotation.gff3","start":108151,"strand":"-","type":"gene"},"OPG128":{"end":109055,"seqid":"resources/genome_annotation.gff3","start":108822,"strand":"-","type":"gene"},"OPG129":{"end":111004,"seqid":"resources/genome_annotation.gff3","start":109070,"strand":"-","type":"gene"},"OPG130":{"end":111902,"seqid":"resources/genome_annotation.gff3","start":111057,"strand":"-","type":"gene"},"OPG131":{"end":112425,"seqid":"resources/genome_annotation.gff3","start":111940,"strand":"+","type":"gene"},"OPG132":{"end":113540,"seqid":"resources/genome_annotation.gff3","start":112422,"strand":"-","type":"gene"},"OPG133":{"end":115696,"seqid":"resources/genome_annotation.gff3","start":113564,"strand":"-","type":"gene"},"OPG134":{"end":116628,"seqid":"resources/genome_annotation.gff3","start":115750,"strand":"+","type":"gene"},"OPG135":{"end":116911,"seqid":"resources/genome_annotation.gff3","start":116609,"strand":"-","type":"gene"},"OPG136":{"end":119587,"seqid":"resources/genome_annotation.gff3","start":116912,"strand":"-","type":"gene"},"OPG137":{"end":120558,"seqid":"resources/genome_annotation.gff3","start":119602,"strand":"+","type":"gene"},"OPG138":{"end":121132,"seqid":"resources/genome_annotation.gff3","start":120560,"strand":"-","type":"gene"},"OPG139":{"end":121368,"seqid":"resources/genome_annotation.gff3","start":121156,"strand":"-","type":"gene"},"OPG140":{"end":121746,"seqid":"resources/genome_annotation.gff3","start":121474,"strand":"-","type":"gene"},"OPG141":{"end":121924,"seqid":"resources/genome_annotation.gff3","start":121763,"strand":"-","type":"gene"},"OPG142":{"end":122198,"seqid":"resources/genome_annotation.gff3","start":121914,"strand":"-","type":"gene"},"OPG143":{"end":123315,"seqid":"resources/genome_annotation.gff3","start":122182,"strand":"-","type":"gene"},"OPG144":{"end":123932,"seqid":"resources/genome_annotation.gff3","start":123318,"strand":"-","type":"gene"},"OPG145":{"end":125425,"seqid":"resources/genome_annotation.gff3","start":123947,"strand":"+","type":"gene"},"OPG146":{"end":125639,"seqid":"resources/genome_annotation.gff3","start":125406,"strand":"-","type":"gene"},"OPG147":{"end":125987,"seqid":"resources/genome_annotation.gff3","start":125640,"strand":"-","type":"gene"},"OPG148":{"end":127266,"seqid":"resources/genome_annotation.gff3","start":125986,"strand":"+","type":"gene"},"OPG149":{"end":127759,"seqid":"resources/genome_annotation.gff3","start":127196,"strand":"+","type":"gene"},"OPG150":{"end":128927,"seqid":"resources/genome_annotation.gff3","start":127779,"strand":"+","type":"gene"},"OPG151":{"end":132418,"seqid":"resources/genome_annotation.gff3","start":128924,"strand":"+","type":"gene"},"OPG153":{"end":137667,"seqid":"resources/genome_annotation.gff3","start":136138,"strand":"-","type":"gene"},"OPG154":{"end":138050,"seqid":"resources/genome_annotation.gff3","start":137718,"strand":"-","type":"gene"},"OPG155":{"end":138491,"seqid":"resources/genome_annotation.gff3","start":138051,"strand":"-","type":"gene"},"OPG156":{"end":139409,"seqid":"resources/genome_annotation.gff3","start":138492,"strand":"-","type":"gene"},"OPG157":{"end":139608,"seqid":"resources/genome_annotation.gff3","start":139372,"strand":"-","type":"gene"},"OPG158":{"end":139769,"seqid":"resources/genome_annotation.gff3","start":139641,"strand":"-","type":"gene"},"OPG159":{"end":140205,"seqid":"resources/genome_annotation.gff3","start":139768,"strand":"+","type":"gene"},"OPG160":{"end":141074,"seqid":"resources/genome_annotation.gff3","start":140172,"strand":"-","type":"gene"},"OPG161":{"end":141647,"seqid":"resources/genome_annotation.gff3","start":141102,"strand":"+","type":"gene"},"OPG162":{"end":142158,"seqid":"resources/genome_annotation.gff3","start":141652,"strand":"+","type":"gene"},"OPG163":{"end":142732,"seqid":"resources/genome_annotation.gff3","start":142202,"strand":"+","type":"gene"},"OPG164":{"end":143464,"seqid":"resources/genome_annotation.gff3","start":142778,"strand":"+","type":"gene"},"OPG165":{"end":144322,"seqid":"resources/genome_annotation.gff3","start":143516,"strand":"+","type":"gene"},"OPG166":{"end":144577,"seqid":"resources/genome_annotation.gff3","start":144398,"strand":"+","type":"gene"},"OPG167":{"end":145407,"seqid":"resources/genome_annotation.gff3","start":144574,"strand":"-","type":"gene"},"OPG170":{"end":146778,"seqid":"resources/genome_annotation.gff3","start":146113,"strand":"-","type":"gene"},"OPG171":{"end":147389,"seqid":"resources/genome_annotation.gff3","start":146988,"strand":"+","type":"gene"},"OPG172":{"end":148017,"seqid":"resources/genome_annotation.gff3","start":147427,"strand":"+","type":"gene"},"OPG173":{"end":148261,"seqid":"resources/genome_annotation.gff3","start":148037,"strand":"+","type":"gene"},"OPG174":{"end":149395,"seqid":"resources/genome_annotation.gff3","start":148355,"strand":"-","type":"gene"},"OPG175":{"end":149819,"seqid":"resources/genome_annotation.gff3","start":149442,"strand":"+","type":"gene"},"OPG176":{"end":150531,"seqid":"resources/genome_annotation.gff3","start":149809,"strand":"+","type":"gene"},"OPG178":{"end":152123,"seqid":"resources/genome_annotation.gff3","start":151509,"strand":"+","type":"gene"},"OPG180":{"end":154371,"seqid":"resources/genome_annotation.gff3","start":152692,"strand":"+","type":"gene"},"OPG181":{"end":155416,"seqid":"resources/genome_annotation.gff3","start":154412,"strand":"+","type":"gene"},"OPG185":{"end":159858,"seqid":"resources/genome_annotation.gff3","start":158917,"strand":"+","type":"gene"},"OPG187":{"end":161533,"seqid":"resources/genome_annotation.gff3","start":160622,"strand":"+","type":"gene"},"OPG188":{"end":163107,"seqid":"resources/genome_annotation.gff3","start":161596,"strand":"+","type":"gene"},"OPG189":{"end":165018,"seqid":"resources/genome_annotation.gff3","start":163333,"strand":"+","type":"gene"},"OPG190":{"end":166075,"seqid":"resources/genome_annotation.gff3","start":165122,"strand":"+","type":"gene"},"OPG191":{"end":166667,"seqid":"resources/genome_annotation.gff3","start":166161,"strand":"+","type":"gene"},"OPG192":{"end":167279,"seqid":"resources/genome_annotation.gff3","start":166731,"strand":"+","type":"gene"},"OPG193":{"end":168137,"seqid":"resources/genome_annotation.gff3","start":167334,"strand":"+","type":"gene"},"OPG195":{"end":168895,"seqid":"resources/genome_annotation.gff3","start":168230,"strand":"+","type":"gene"},"OPG197":{"end":169972,"seqid":"resources/genome_annotation.gff3","start":169670,"strand":"+","type":"gene"},"OPG198":{"end":170886,"seqid":"resources/genome_annotation.gff3","start":170038,"strand":"+","type":"gene"},"OPG199":{"end":172022,"seqid":"resources/genome_annotation.gff3","start":170988,"strand":"+","type":"gene"},"OPG200":{"end":172599,"seqid":"resources/genome_annotation.gff3","start":172150,"strand":"+","type":"gene"},"OPG204":{"end":175587,"seqid":"resources/genome_annotation.gff3","start":174532,"strand":"+","type":"gene"},"OPG205":{"end":178019,"seqid":"resources/genome_annotation.gff3","start":175656,"strand":"+","type":"gene"},"OPG208":{"end":180339,"seqid":"resources/genome_annotation.gff3","start":179266,"strand":"+","type":"gene"},"OPG209":{"end":181090,"seqid":"resources/genome_annotation.gff3","start":180518,"strand":"+","type":"gene"},"OPG210":{"end":186998,"seqid":"resources/genome_annotation.gff3","start":181356,"strand":"+","type":"gene"},"nuc":{"end":197209,"start":1,"strand":"+","type":"source"}},"colorings":[{"key":"clade_membership","title":"Clade","type":"categorical","scale":[["IIb","#DEA73C"]]},{"key":"gt","title":"Genotype","type":"categorical"},{"key":"outbreak","title":"Outbreak","type":"categorical","scale":[["hMPXV-1","#4C90C0"]]},{"key":"lineage","title":"Lineage","type":"categorical","scale":[["A","#5E1D9D"],["A.1","#4D22AE"],["A.1.1","#4531BC"],["B.1","#4041C7"],["B.1.1","#3F53CD"],["B.1.2","#4064CF"],["B.1.3","#4375CD"],["C.1","#4784C8"],["B.1.4","#4C91BF"],["B.1.5","#539CB4"],["B.1.6","#5AA5A7"],["B.1.7","#63AC9A"],["B.1.8","#6CB28C"],["B.1.9","#77B67E"],["B.1.10","#82BA71"],["B.1.11","#8FBC66"],["B.1.12","#9CBE5B"],["B.1.13","#A9BD53"],["B.1.14","#B5BD4C"],["B.1.15","#C1BA46"],["B.1.16","#CDB642"],["B.1.17","#D6B03F"],["B.1.18","#DEA73B"],["B.1.19","#E39B39"],["B.1.20","#E68D36"],["A.2","#E67C33"],["A.2.1","#E5692F"],["A.2.2","#E1532B"],["A.2.3","#DE3E27"],["A.3","#DB2823"]]},{"key":"date","title":"Collection Date","type":"categorical"},{"key":"host","title":"Host","type":"categorical"},{"key":"strain","title":"Strain name","type":"categorical"},{"key":"strain_display","title":"Pretty strain name","type":"categorical"},{"key":"region","title":"Region","type":"categorical","scale":[["Asia","#447CCD"],["Oceania","#5EA9A1"],["Africa","#8ABB6A"],["Europe","#BEBB48"],["South America","#E29E39"],["North America","#E2562B"]]},{"key":"country","title":"Country","type":"categorical","scale":[["Israel","#5E1D9D"],["Singapore","#4E21AD"],["Vietnam","#462EB9"],["Taiwan","#403CC5"],["South Korea","#3F4CCB"],["Japan","#3E5DD0"],["Australia","#416CCE"],["Benin","#447BCD"],["Nigeria","#4887C6"],["South Africa","#4D93BE"],["Portugal","#539CB3"],["Ireland","#5AA5A8"],["Spain","#62AB9C"],["United Kingdom","#6AB18F"],["France","#74B582"],["Belgium","#7EB876"],["Netherlands","#89BB6B"],["Switzerland","#94BD61"],["Germany","#A0BE59"],["Italy","#ABBD51"],["Slovenia","#B7BD4B"],["Sweden","#C2BA46"],["Austria","#CCB742"],["Czech Republic","#D5B13F"],["Slovakia","#DDAA3C"],["Romania","#E19F3A"],["Finland","#E69537"],["Brazil","#E68534"],["Peru","#E67631"],["Colombia","#E4632E"],["Mexico","#E14F2A"],["USA","#DE3C26"],["Canada","#DB2823"]]}],"filters":["clade_membership","lineage","country","host","institution","region","strain_display","strain","date","outbreak"],"panels":["tree","entropy"],"extensions":{"nextclade":{"clade_node_attrs":[{"name":"outbreak","displayName":"Outbreak","description":""},{"name":"lineage","displayName":"Lineage","description":""}],"placement_mask_ranges":[{"begin":0,"end":1500},{"begin":133050,"end":133250},{"begin":136500,"end":136600},{"begin":140050,"end":140250},{"begin":146750,"end":147000},{"begin":150500,"end":150650},{"begin":169250,"end":169500},{"begin":169700,"end":169800},{"begin":173150,"end":173350},{"begin":179000,"end":179300},{"begin":190787,"end":197209}]}}},"tree":{"name":"NODE_0000001","node_attrs":{"div":0,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{},"labels":{"clade":"A"}},"children":[{"name":"NC_063383","node_attrs":{"div":0,"accession":"NC_063383","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Senkevich,T.G.,Yutin,N.,Wolf,Y.I.,Koonin,E.V.,Moss,B.,Zmasek,C.M.,Knipe,D.M.,Pellett,P.E.,Scheuermann,R.H.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Senkevich,T.G.,Yutin,N.,Wolf,Y.I.,Koonin,E.V.,Moss,B.,Zmasek,C.M.,Knipe,D.M.,Pellett,P.E.,Scheuermann,R.H."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Center for Biotechnology Information, NIH"},"lineage":{"value":"A"},"strain":{"value":"MPXV-M5312_HM12_Rivers"},"date":{"value":"2018-08-XX"},"strain_display":{"value":"Nigeria/NC_063383/2018-08-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000000","node_attrs":{"div":0,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{}},"children":[{"name":"NC_063383.1","node_attrs":{"div":0,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000002","node_attrs":{"div":5,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["T608-","T609-","A18769G","T28175C","A81977G","A100261G","T146895-","T146897-","T146898-","T146899-","T146900-","T146902-","T146903-","T146904-","T146905-","T146907-","T146909-","T146910-","T146911-","T146912-","T154408C","A196616-","A196617-"],"OPG118":["K606E"]},"labels":{"aa":"OPG118: K606E"}},"children":[{"name":"KJ642617","node_attrs":{"div":38,"accession":"KJ642617","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"Nigeria"},"clade_membership":{"value":"outgroup"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"KJ642617"},"date":{"value":"1971-XX-XX"},"strain_display":{"value":"Nigeria/KJ642617/1971-XX-XX"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T607-","A3450G","A8893C","G13625A","A18312G","T19367C","A32210-","C32211-","G32212-","T33143C","A38067G","A46895G","G48138A","A48527C","A53207C","A66580G","T80986C","C92516T","G98489-","C98727T","T100562C","C105126T","T119718C","A128076G","A129762G","T133145C","T136555C","A137627G","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","A141300G","T141364C","A142450C","C146687T","A146894-","A146896-","A146901-","A146906-","A146908-","G149744A","G149878A","A158170-","G160174T","C160852T","A160867G","T166656-","T166657-","T167656G","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","A171675G","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","A178423G","A181253-","T187080-","T193760C","A196615-"],"OPG025":["T548M"],"OPG049":["R314-"],"OPG056":["V323A"],"OPG071":["L411W"],"OPG084":["Q620R"],"OPG104":["T12A"],"OPG150":["N100D"],"OPG151":["D280G"],"OPG153":["M14T"],"OPG159":["N124-","Y125-","N126-"],"OPG161":["K67E","V88A"],"OPG170":["G31D"],"OPG176":["D24N"],"OPG191":["F166-"],"OPG193":["I108R"],"OPG197":["T34-","D35-"],"OPG199":["K230E"]},"labels":{"aa":"OPG025: T548M; OPG049: R314-; OPG056: V323A; OPG071: L411W; OPG084: Q620R; OPG104: T12A; OPG150: N100D; OPG151: D280G; OPG153: M14T; OPG159: N124-, Y125-, N126-; OPG161: K67E, V88A; OPG170: G31D; OPG176: D24N; OPG191: F166-; OPG193: I108R; OPG197: T34-, D35-; OPG199: K230E","clade":"outgroup"}}},{"name":"OP535336","node_attrs":{"div":13,"accession":"OP535336","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2017_2946"},"date":{"value":"2017-10-XX"},"strain_display":{"value":"Nigeria/OP535336/2017-10-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C8634T","C33332T","C67253T","C110326T","C117099T","C122737T","G125303A","G129583A","A136552-","T136553-","C136554-","A146894-","A146896-","A146901-","A146906-","A146908-","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","T178048-"],"OPG050":["R26Q"],"OPG085":["D427N"],"OPG129":["E227K"],"OPG136":["R830Q"],"OPG145":["D453N"],"OPG153":["D385-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG050: R26Q; OPG085: D427N; OPG129: E227K; OPG136: R830Q; OPG145: D453N; OPG153: D385-; OPG197: T34-, D35-"}}},{"name":"NODE_0000003","node_attrs":{"div":8,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["C5157T","G7764A","G9782A","C133161T","A146894-","A146896-","A146901-","A146906-","A146908-","G192053A"],"OPG015":["D334N"],"OPG015_dup":["D334N"],"OPG019":["R62K"],"OPG021":["A66T"]},"labels":{"aa":"OPG015: D334N; OPG015_dup: D334N; OPG019: R62K; OPG021: A66T"}},"children":[{"name":"MK783031","node_attrs":{"div":9,"accession":"MK783031","author":{"author":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J.","value":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"NCEZID/DHCPP/PRB, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A"},"strain":{"value":"MK783031"},"date":{"value":"2017-11-09"},"strain_display":{"value":"Nigeria/MK783031/2017-11-09"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G109736A"]}}},{"name":"MK783027","node_attrs":{"div":8,"accession":"MK783027","author":{"author":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J.","value":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, NCEZID/DHCPP/PRB"},"lineage":{"value":"A"},"strain":{"value":"MK783027"},"date":{"value":"2017-11-09"},"strain_display":{"value":"Nigeria/MK783027/2017-11-09"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000004","node_attrs":{"div":8,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["G51559A","C60923T","G179884A"],"OPG080":["E366K"],"OPG208":["E207K"]},"labels":{"aa":"OPG080: E366K; OPG208: E207K"}},"children":[{"name":"MT903337","node_attrs":{"div":10,"accession":"MT903337","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A"},"strain":{"value":"MPXV-M2940_FCT"},"date":{"value":"2018-XX-XX"},"strain_display":{"value":"Nigeria/MT903337/2018-XX-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A146894-","A146896-","A146901-","A146906-","A146908-","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","G172784A","T181577C"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"OP535318","node_attrs":{"div":12,"accession":"OP535318","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2017_5227"},"date":{"value":"2017-12-XX"},"strain_display":{"value":"Nigeria/OP535318/2017-12-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-608T","C23311T","G75512A","G124715A","-146895T","-146897T","-146898T","-146899T","-146900T","-146902T","-146903T","-146904T","-146905T","-146907T","-146909T","-146910T","-146911T","-146912T","G162165A","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","-196616A"],"OPG039":["E270K"],"OPG095":["R237K"],"OPG145":["D257N"]},"labels":{"aa":"OPG039: E270K; OPG095: R237K; OPG145: D257N"}}},{"name":"OP535326","node_attrs":{"div":14,"accession":"OP535326","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2018_5315"},"date":{"value":"2018-06-XX"},"strain_display":{"value":"Nigeria/OP535326/2018-06-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C23000T","G29826A","C109667T","A136552-","T136553-","C136554-","-146895T","-146897T","-146898T","-146899T","-146900T","-146902T","-146903T","-146904T","-146905T","-146907T","-146909T","-146910T","-146911T","-146912T","G147459A","G155644A","G177009A","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG038":["G54S"],"OPG047":["R457C"],"OPG153":["D385-"],"OPG205":["E452K"]},"labels":{"aa":"OPG038: G54S; OPG047: R457C; OPG153: D385-; OPG205: E452K"}}},{"name":"NODE_0000005","node_attrs":{"div":17,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["T607-","C101683T","C127245T","T157146A","T158362-","T158506G","T158508G","T158517G","G158527A","G178814A","G178988A","A196615-"],"OPG149":["S17L"]},"labels":{"aa":"OPG149: S17L"}},"children":[{"name":"OP535334","node_attrs":{"div":17,"accession":"OP535334","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2018_5223"},"date":{"value":"2018-02-XX"},"strain_display":{"value":"Nigeria/OP535334/2018-02-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-146895T","-146897T","-146898T","-146899T","-146900T","-146902T","-146903T","-146904T","-146905T","-146907T","-146909T","-146910T","-146911T","-146912T","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-"]}}},{"name":"OP535314","node_attrs":{"div":17,"accession":"OP535314","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2018_5220"},"date":{"value":"2018-01-XX"},"strain_display":{"value":"Nigeria/OP535314/2018-01-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A146894-","A146896-","A146901-","A146906-","A146908-","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}}]}]},{"name":"NODE_0000006","node_attrs":{"div":11,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["C8385T","G37209A","G43118A","G48180A","C113841T","A136552-","T136553-","C136554-","C146607T","-146895T","-146897T","-146898T","-146899T","-146900T","-146902T","-146903T","-146904T","-146905T","-146907T","-146909T","-146910T","-146911T","-146912T","T169721-","A169723-","A169725-","T169726-","A169727-","A169729-","A169731-","T169732-","A179198-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-"],"OPG056":["S609F"],"OPG133":["G619E"],"OPG153":["D385-"],"OPG170":["E58K"]},"labels":{"aa":"OPG056: S609F; OPG133: G619E; OPG153: D385-; OPG170: E58K"}},"children":[{"name":"OP535328","node_attrs":{"div":11,"accession":"OP535328","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2018_5306"},"date":{"value":"2018-03-XX"},"strain_display":{"value":"Nigeria/OP535328/2018-03-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C169722-","G169724-","C169728-","G169730-","C179199-","C179208-","C179217-"],"OPG197":["S18-","D19-","T20-","D21-"]},"labels":{"aa":"OPG197: S18-, D19-, T20-, D21-"}}},{"name":"NODE_0000007","node_attrs":{"div":12,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["G29889A","T76087-","A89106-","-169721T","-169723A","-169725A","-169726T","-169727A","-169729A","-169731A","-169732T","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T"],"OPG047":["P436S"]},"labels":{"aa":"OPG047: P436S"}},"children":[{"name":"NODE_0000008","node_attrs":{"div":15,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-","C40251T","C63801T","T121121-","G162243A","-196616A"],"OPG058":["D62N"],"OPG083":["E306K"]},"labels":{"aa":"OPG058: D62N; OPG083: E306K"}},"children":[{"name":"OP612684","node_attrs":{"div":18,"accession":"OP612684","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A"},"strain":{"value":"MPXV/046/19"},"date":{"value":"2019-05-XX"},"strain_display":{"value":"Nigeria/OP612684/2019-05-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C92830T","A136543-","T136544-","C136545-","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","-173288A","-173289T","G180656A","G186423A","-196617A"],"OPG113":["S367F"],"OPG153":["D382-","D383-","D384-"],"OPG209":["D47N"],"OPG210":["E1690K"]},"labels":{"aa":"OPG113: S367F; OPG153: D382-, D383-, D384-; OPG209: D47N; OPG210: E1690K"}}},{"name":"OP612680","node_attrs":{"div":17,"accession":"OP612680","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A"},"strain":{"value":"MPXV/021/19"},"date":{"value":"2019-04-01"},"strain_display":{"value":"Nigeria/OP612680/2019-04-01"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C63264T","-89106A","T104748C","T133098-","T133099-","T133100-","T133101-","T133102-","T187080-"],"OPG123":["D108G"]},"labels":{"aa":"OPG123: D108G"}}}]},{"name":"NODE_0000009","node_attrs":{"div":15,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","C28164T","C87027T","G121454A"],"OPG044":["S25F"]},"labels":{"aa":"OPG044: S25F"}},"children":[{"name":"OP612678","node_attrs":{"div":18,"accession":"OP612678","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A"},"strain":{"value":"MPXV/017/19"},"date":{"value":"2019-03-14"},"strain_display":{"value":"Nigeria/OP612678/2019-03-14"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G46685A","G144659A","G165688A","T187080-","A196614-","A196615-"],"OPG167":["S250F"]},"labels":{"aa":"OPG167: S250F"}}},{"name":"NODE_0000010","node_attrs":{"div":17,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["G3531A","-76087T","T151621G","T179068A","-196616A","-196617A"],"OPG178":["F38C"]},"labels":{"aa":"OPG178: F38C"}},"children":[{"name":"OP612675","node_attrs":{"div":18,"accession":"OP612675","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A"},"strain":{"value":"MPXV/007/19"},"date":{"value":"2019-01-30"},"strain_display":{"value":"Nigeria/OP612675/2019-01-30"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T4676C","-89106A","-136552A","-136553T","-136554C","C193679T"]}}},{"name":"OP612676","node_attrs":{"div":17,"accession":"OP612676","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A"},"strain":{"value":"MPXV/013/19"},"date":{"value":"2019-02-20"},"strain_display":{"value":"Nigeria/OP612676/2019-02-20"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A19360-","A23252-","T133100-","T133101-","T133102-","A138474-","A156769-","T163332-","A173514-","A173515-","G173516-","A173517-","A173518-","G173519-","A173520-","C173521-","G173522-","A173523-","G173524-","G173525-","A173526-","C173527-","G173528-","G173529-","A173530-","G173531-","A173532-","C173533-","G173534-","G173535-","T173536-","A173537-","G173538-","A173539-","A173540-","T173541-","A173542-","A173543-","T179072A"]}}}]}]}]}]},{"name":"NODE_0000011","node_attrs":{"div":21,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-","C13298T","C18792T","C30636T","C34472T","C34578T","G80099A","G93387A","G114659A","G124031A","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","-146895T","-146897T","-146898T","-146899T","-146900T","-146902T","-146903T","-146904T","-146905T","-146907T","-146909T","-146910T","-146911T","-146912T","C148529-","A148530-","T148531-","A148532-","T148533-","C148534-","A148535-","G149265A","C149872T","G154015A","C161953T","C165782T","G168205A","C177720T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A196614-","A196615-"],"OPG031":["D13N"],"OPG047":["D187N"],"OPG053":["G38E"],"OPG113":["E553K"],"OPG145":["D29N"],"OPG153":["D383-","D384-","D385-"],"OPG174":["S44L","D288-","M289-"],"OPG176":["Q22*"],"OPG180":["D442N"],"OPG188":["H120Y"],"OPG190":["P221S"],"OPG205":["R689C"]},"labels":{"aa":"OPG031: D13N; OPG047: D187N; OPG053: G38E; OPG113: E553K; OPG145: D29N; OPG153: D383-, D384-, D385-; OPG174: S44L, D288-, M289-; OPG176: Q22*; OPG180: D442N; OPG188: H120Y; OPG190: P221S; OPG205: R689C","clade":"A.2"}},"children":[{"name":"ON675438","node_attrs":{"div":43,"accession":"ON675438","author":{"author":"Gigante,C.M.,Griffin-Thomas,L.A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Crain,J.,Li,Y.","value":"Gigante,C.M.,Griffin-Thomas,L.A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Crain,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A.2"},"strain":{"value":"MPXV_USA_2022_VA001"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/ON675438/2022-05-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-606T","-607T","G11332A","G12099A","C13648T","C15105T","C16227T","C29887T","C42101T","G64216A","G75614A","C117119T","C128534T","G130454A","C134442T","C142918T","G144446A","C156429T","C164832T","C168532T","G174610A","A175231-","T175232-","C175233-","G175234-","T175235-","A175236-","G175237-","T175238-","A175239-","T175240-","C175241-","A175242-","A175243-","G175244-","A175245-","T175246-","G175247-","T175248-","A175249-","A175250-","A175251-","A175252-","T175253-","A175254-","C175255-","T175256-","T175257-","A175258-","C175259-","G175260-","G175261-","T175262-","T175263-","A175264-","T175265-","A175266-","C175267-","C175268-","G175269-","T175270-","C175271-","A175272-","C175273-","A175274-","A175275-","G175276-","A175277-","C175278-","C175279-","A175280-","C175281-","A175282-","G175283-","G175284-","T175285-","T175286-","T175287-","A175288-","A175289-","A175290-","C175291-","T175292-","A175293-","A175294-","T175295-","A175296-","C175297-","T175298-","A175299-","G175300-","A175301-","T175302-","C175303-","C175304-","G175305-","A175306-","A175307-","A175308-","A175309-","T175310-","C175311-","A175312-","A175313-","C175314-","G175315-","T175316-","A175317-","A175318-","C175319-","G175320-","A175321-","T175322-","A175323-","G175324-","G175325-","A175326-","G175327-","A175328-","A175329-","C175330-","C175331-","T175332-","G175333-","C175334-","C175335-","A175336-","A175337-","T175338-","A175339-","T175340-","A175341-","A175342-","C175343-","A175344-","T175345-","G175346-","C175347-","A175348-","G175349-","T175350-","G175351-","C175352-","T175353-","G175354-","T175355-","G175356-","T175357-","C175358-","A175359-","A175360-","C175361-","G175362-","T175363-","C175364-","A175365-","T175366-","T175367-","A175368-","T175369-","T175370-","T175371-","G175372-","T175373-","C175374-","G175375-","A175376-","C175377-","G175378-","A175379-","T175380-","G175381-","T175382-","A175383-","C175384-","T175385-","G175386-","A175387-","T175388-","T175389-","G175390-","A175391-","A175392-","T175393-","G175394-","G175395-","G175396-","A175397-","A175398-","A175399-","A175400-","T175401-","C175402-","C175403-","A175404-","T175405-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A179628G","C179853T","G188544A","-196614A"],"OPG023":["R268*"],"OPG025":["D55N","M540I"],"OPG027":["D51N"],"OPG062":["S52L"],"OPG096":["D10N"],"OPG151":["E511K"],"OPG166":["D17N"],"OPG204":["E27K","I234-","V235-","V236-","S237-","R238-","C239-","K240-","I241-","L242-","T243-","V244-","I245-","P246-","S247-","Q248-","D249-","H250-","R251-","F252-","K253-","L254-","I255-","L256-","D257-","P258-","K259-","I260-","N261-","V262-","T263-","I264-","G265-","E266-","P267-","A268-","N269-","I270-","T271-","C272-","S273-","A274-","V275-","S276-","T277-","S278-","L279-","F280-","V281-","D282-","D283-","V284-","L285-","I286-","E287-","W288-","E289-","N290-","P291-","S292-"]},"labels":{"aa":"OPG023: R268*; OPG025: D55N, M540I; OPG027: D51N; OPG062: S52L; OPG096: D10N; OPG151: E511K; OPG166: D17N; OPG204: E27K, I234-, V235-, V236-, S237-, R238-, C239-, K240-, I241-, L242-, T243-, V244-, I245-, P246-, S247-, Q248-, D249-, H250-, R251-, F252-, K253-, L254-, I255-, L256-, D257-, P258-, K259-, I260-, N261-, V262-, T263-, I264-, G265-, E266-, P267-, A268-, N269-, I270-, T271-, C272-, S273-, A274-, V275-, S276-, T277-, S278-, L279-, F280-, V281-, D282-, D283-, V284-, L285-, I286-, E287-, W288-, E289-, N290-, P291-, S292-"}}},{"name":"OP612689","node_attrs":{"div":22,"accession":"OP612689","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.2"},"strain":{"value":"MPXV/111/19"},"date":{"value":"2019-12-17"},"strain_display":{"value":"Nigeria/OP612689/2019-12-17"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G144876A","G173355-","A173356-","G173357-","G173358-","T173359-","A173360-","C173361-","G173362-","G173363-","G173364-","A173365-","T173366-","A173367-","G173368-","A173369-","A173370-","T173371-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG167":["P178S"]},"labels":{"aa":"OPG167: P178S"}}},{"name":"NODE_0000012","node_attrs":{"div":36,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.3"}},"branch_attrs":{"mutations":{"nuc":["G2752A","G39173A","C57284T","G61844A","C74226T","G118739A","C146223T","G148427A","G150800A","G168365A","G170317A","G172527A","C175759T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G189417A","C189474T","C194458T"],"OPG075":["R72K"],"OPG170":["D186N"],"OPG195":["E46K"],"OPG198":["D94N"],"OPG205":["A35V"]},"labels":{"aa":"OPG075: R72K; OPG170: D186N; OPG195: E46K; OPG198: D94N; OPG205: A35V","clade":"A.2.3"}},"children":[{"name":"ON676707","node_attrs":{"div":39,"accession":"ON676707","author":{"author":"Gigante,C.M.,Stringer,J.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Schulte,J.,Li,Y.","value":"Gigante,C.M.,Stringer,J.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Schulte,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A.2.3"},"strain":{"value":"MPXV_USA_2021_TX"},"date":{"value":"2021-07-XX"},"strain_display":{"value":"USA/ON676707/2021-07-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-606T","C100640T","G142636A","C186104T","-196614A"]}}},{"name":"OP555515","node_attrs":{"div":49,"accession":"OP555515","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"A.2.3"},"strain":{"value":"Monkeypox/PT0428/2022"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Portugal/OP555515/2022-08-01"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C30669T","C45028T","G49377A","G95355A","C121320T","G136132A","-136546A","-136547T","-136548C","G142265A","C159143T","C162264T","C170573T","C180686T","C181216T","G188229A"],"OPG047":["E176K"],"OPG064":["E291K"],"OPG068":["D393N"],"OPG139":["A17T"],"OPG153":["-383D"],"OPG163":["D22N"],"OPG185":["S76F"],"OPG198":["S179L"],"OPG209":["Q57*"]},"labels":{"aa":"OPG047: E176K; OPG064: E291K; OPG068: D393N; OPG139: A17T; OPG153: -383D; OPG163: D22N; OPG185: S76F; OPG198: S179L; OPG209: Q57*"}}}]},{"name":"NODE_0000013","node_attrs":{"div":41,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.2"}},"branch_attrs":{"mutations":{"nuc":["G11948A","C14790T","G21991A","G23118A","G38923A","G39515A","G56546A","G57786A","G93312A","C103019T","C112470T","C124129T","C127906T","G135303A","G145902A","C149365T","G155611A","G158424A","G162640A","G186984A"],"OPG023":["S318F"],"OPG025":["D160N"],"OPG037":["S148L"],"OPG056":["R38C"],"OPG113":["V528I"],"OPG122":["H198Y"],"OPG132":["M357I"],"OPG150":["S43L"],"OPG153":["D382-"],"OPG174":["G11R"],"OPG188":["G349S"],"OPG210":["D1877N"]},"labels":{"aa":"OPG023: S318F; OPG025: D160N; OPG037: S148L; OPG056: R38C; OPG113: V528I; OPG122: H198Y; OPG132: M357I; OPG150: S43L; OPG153: D382-; OPG174: G11R; OPG188: G349S; OPG210: D1877N","clade":"A.2.2"}},"children":[{"name":"OP422632","node_attrs":{"div":45,"accession":"OP422632","author":{"author":"Martin,F.,Anges,Y.,Benjamin,H.,Amadou,S.A.,Ousmane,F.","value":"Martin,F.,Anges,Y.,Benjamin,H.,Amadou,S.A.,Ousmane,F."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Benin"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institut Pasteur de Dakar, Virology Department"},"lineage":{"value":"A.2.2"},"strain":{"value":"MPXV-SEN0022"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Benin/OP422632/2022-06-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T4619C","C4623-","T4624-","T4625-","T4626-","T4627-","T4628-","C4629-","A4630-","T4631-","A4632-","A4633-","T4634-","T4635-","A4636-","G4637-","A4638-","G4639-","A4640-","A4641-","A4642-","A4643-","A4644-","G4645-","A4646-","T4647-","C4648-","A4649-","A4650-","G4651-","G4652-","T4653-","A4654-","T4655-","A4656-","A4657-","A4658-","A4659-","A4660-","T4661-","T4662-","A4663-","G4664-","A4665-","A4666-","G4667-","T4668-","G4669-","T4670-","T4671-","A4672-","G4673-","A4674-","C4675-","T4676-","A4677-","T4678-","A4679-","A4680-","C32643T","-136546A","-136547T","-136548C","-136549A","-136550T","-136551C","-136552A","-136553T","-136554C","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","G146913-","T146914-","A146915-","-148529C","-148530A","-148531T","-148532A","-148533T","-148534C","-148535A","C156429T","G172501A","T196689-"],"OPG049":["R170K"],"OPG153":["-382D","-383D","-384D","-385D"],"OPG174":["-288D","-289M"],"OPG200":["E118K"]},"labels":{"aa":"OPG049: R170K; OPG153: -382D, -383D, -384D, -385D; OPG174: -288D, -289M; OPG200: E118K"}}},{"name":"OP450997","node_attrs":{"div":48,"accession":"OP450997","author":{"author":"Gigante,C.M.,Xia,D.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y.","value":"Gigante,C.M.,Xia,D.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"A.2.2"},"strain":{"value":"MPXV_USA_2022_PA0016"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OP450997/2022-07-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G451A","G20576A","C20581T","G67351A","G78259A","G94479A","C133402T","A136543-","T136544-","C136545-","C176148T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C196759T"],"OPG036":["E162K"],"OPG085":["S394F"],"OPG205":["H165Y"]},"labels":{"aa":"OPG036: E162K; OPG085: S394F; OPG205: H165Y"}}},{"name":"NODE_0000014","node_attrs":{"div":46,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.2"}},"branch_attrs":{"mutations":{"nuc":["C13686T","C21861T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G151112A","G174721A","C188491T"],"OPG025":["E528K"],"OPG037":["M191I"],"OPG204":["A64T"]},"labels":{"aa":"OPG025: E528K; OPG037: M191I; OPG204: A64T"}},"children":[{"name":"OP331336","node_attrs":{"div":50,"accession":"OP331336","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"A.2.2"},"strain":{"value":"MPXV_UK_2022_9000166"},"date":{"value":"2022-06-29"},"strain_display":{"value":"United Kingdom/OP331336/2022-06-29"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C27826T","G59282A","C65743A","G85356A","A136543-","T136544-","C136545-"],"OPG043":["E44K"],"OPG084":["P341H"],"OPG106":["S48F"]},"labels":{"aa":"OPG043: E44K; OPG084: P341H; OPG106: S48F"}}},{"name":"OR113690","node_attrs":{"div":56,"accession":"OR113690","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Austria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"lineage":{"value":"A.2.2"},"strain":{"value":"hMPXV/Austria/MUW1607960/2023"},"date":{"value":"2023-04-05"},"strain_display":{"value":"Austria/OR113690/2023-04-05"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C18102T","C52429T","C86957T","G97318A","C121394T","G129982A","-136546A","-136547T","-136548C","-136549A","-136552A","-136553T","-136554C","G146714A","C148895A","G165892A","G175471A"],"OPG031":["D243N"],"OPG108":["D35N"],"OPG117":["D424N"],"OPG170":["A22V"],"OPG174":["M167I"],"OPG204":["E314K"]},"labels":{"aa":"OPG031: D243N; OPG108: D35N; OPG117: D424N; OPG170: A22V; OPG174: M167I; OPG204: E314K"}}}]}]},{"name":"NODE_0000015","node_attrs":{"div":22,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2"}},"branch_attrs":{"mutations":{"nuc":["-606T","-607T","-608T","C25072T","A136543-","T136544-","C136545-"],"OPG040":["R136Q"],"OPG153":["D382-"]},"labels":{"aa":"OPG040: R136Q; OPG153: D382-"}},"children":[{"name":"OP612691","node_attrs":{"div":24,"accession":"OP612691","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.2"},"strain":{"value":"MPXV/191/20"},"date":{"value":"2020-01-XX"},"strain_display":{"value":"Nigeria/OP612691/2020-01-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-609T","C90329T","C132520T","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG111":["S22L"]},"labels":{"aa":"OPG111: S22L"}}},{"name":"NODE_0000016","node_attrs":{"div":35,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["G36898A","G42183A","C42903T","G50346A","C54268T","C73616T","G79406A","G105746A","A140492C","C142498T","C157737T","C161152T","A169763-","C169764-","A169765-","G169766-","A169767-","T169768-","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","C179537T","-196614A","-196615A"],"OPG062":["M79I"],"OPG063":["M262I"],"OPG069":["D121N"],"OPG102":["D108N"],"OPG160":["S195A"],"OPG197":["T32-","D33-","T34-","D35-"],"OPG208":["S91L"]},"labels":{"aa":"OPG062: M79I; OPG063: M262I; OPG069: D121N; OPG102: D108N; OPG160: S195A; OPG197: T32-, D33-, T34-, D35-; OPG208: S91L","clade":"A.2.1"}},"children":[{"name":"NODE_0000017","node_attrs":{"div":36,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["T95936A"],"OPG116":["D192E"]},"labels":{"aa":"OPG116: D192E"}},"children":[{"name":"ON674051","node_attrs":{"div":38,"accession":"ON674051","author":{"author":"Gigante,C.M.,Lee,P.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A.2.1"},"strain":{"value":"MPXV_USA_2022_FL001"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/ON674051/2022-05-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T608-","C112544T","G163540A"],"OPG132":["D333N"],"OPG189":["E70K"]},"labels":{"aa":"OPG132: D333N; OPG189: E70K"}}},{"name":"OR459777","node_attrs":{"div":44,"accession":"OR459777","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"South Korea"},"clade_membership":{"value":"IIb"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"lineage":{"value":"A.2.1"},"strain":{"value":"MPXV-ROK-P004-2022"},"date":{"value":"2022-11-22"},"strain_display":{"value":"South Korea/OR459777/2022-11-22"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-609T","A46522G","G52289A","G67261A","C72231T","C115379T","C135822T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G181947A","G182189A","-196616A","-196617A"],"OPG071":["T717I"],"OPG085":["S424L"],"OPG210":["D198N"]},"labels":{"aa":"OPG071: T717I; OPG085: S424L; OPG210: D198N"}}}]},{"name":"NODE_0000018","node_attrs":{"div":36,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C184924T","-196616A","-196617A"],"OPG210":["S1190L"]},"labels":{"aa":"OPG210: S1190L"}},"children":[{"name":"OP936000","node_attrs":{"div":45,"accession":"OP936000","author":{"author":"Nguyen,D.T.,Le,H.M.,Huynh,H.T.T.,Tang,T.C.,Le,N.H.,Nguyen,H.H.,Nghiem,N.M.,Nguyen,H.T.T.,Vo,Q.T.,Vu,T.T.K.,Nguyen,T.T.,Phan,T.V.,Nguyen,T.L.N.,Le,T.M.,Vo,Q.M.,Dinh,M.N.H.,Nguyen,P.T.,Tran,P.T.L.,Tran,T.T.T.,Pham,T.T.N.,Nguyen,T.H.,Truong,L.T.T.,Nguyen,H.N.T.,Tran,T.T.,Le,K.T.T.,Lam,Y.M.,Thwaites,G.,Thwaites,L.,Nguyen,C.V.V.,Nguyen,A.T.,Le,T.V.","value":"Nguyen,D.T.,Le,H.M.,Huynh,H.T.T.,Tang,T.C.,Le,N.H.,Nguyen,H.H.,Nghiem,N.M.,Nguyen,H.T.T.,Vo,Q.T.,Vu,T.T.K.,Nguyen,T.T.,Phan,T.V.,Nguyen,T.L.N.,Le,T.M.,Vo,Q.M.,Dinh,M.N.H.,Nguyen,P.T.,Tran,P.T.L.,Tran,T.T.T.,Pham,T.T.N.,Nguyen,T.H.,Truong,L.T.T.,Nguyen,H.N.T.,Tran,T.T.,Le,K.T.T.,Lam,Y.M.,Thwaites,G.,Thwaites,L.,Nguyen,C.V.V.,Nguyen,A.T.,Le,T.V."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Vietnam"},"clade_membership":{"value":"IIb"},"institution":{"value":"EI group, Oxford University Clinica Research Unit"},"lineage":{"value":"A.2.1"},"strain":{"value":"Mpox-HCMC-M157"},"date":{"value":"2022-09-26"},"strain_display":{"value":"Vietnam/OP936000/2022-09-26"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["T647-","G648-","C32252T","G51559A","A86823T","G103706A","C152033T","T167015G","A167020T","A167021-","C167022-","G167029C","A187574C"]}}},{"name":"NODE_0000019","node_attrs":{"div":37,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["G43103A","A136540-","T136541-","C136542-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"],"OPG063":["P196S"],"OPG153":["D381-"]},"labels":{"aa":"OPG063: P196S; OPG153: D381-"}},"children":[{"name":"OR455100","node_attrs":{"div":43,"accession":"OR455100","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"A.2.1"},"strain":{"value":"MpxV/human/USA/WA-UW-081251/2023"},"date":{"value":"2023-08-XX"},"strain_display":{"value":"USA/OR455100/2023-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-609T","C29438T","G58696A","G120906A","G147352A","G178102A","C187942T","A192392-","A192393-","A192394-","T192395-","G192396-","A192397-","G192398-","T192399-","T192400-","A192401-","A192402-","T192403-","A192404-","G192405-"],"OPG046":["V98I"],"OPG078":["S39L"],"OPG138":["S76F"],"OPG171":["R122K"]},"labels":{"aa":"OPG046: V98I; OPG078: S39L; OPG138: S76F; OPG171: R122K"}}},{"name":"NODE_0000020","node_attrs":{"div":39,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["G30868A","G102599A","-133098T","-133099T","-133100T","-169763A","-169764C","-169765A","-169766G","-169767A","-169768T","-169769A","-169770C","-169771A","-169772G","-169773A","-169774T"],"OPG122":["D58N"],"OPG197":["-32T","-33D","-34T","-35D"]},"labels":{"aa":"OPG122: D58N; OPG197: -32T, -33D, -34T, -35D"}},"children":[{"name":"OP331335","node_attrs":{"div":40,"accession":"OP331335","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"A.2.1"},"strain":{"value":"MPXV_UK_2022_9000155"},"date":{"value":"2022-06-03"},"strain_display":{"value":"United Kingdom/OP331335/2022-06-03"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T607-","T608-","-133101T","-133102T","-136540A","-136541T","-136542C","-136543A","-136544T","-136545C","-136546A","-136547T","-136548C","-136549A","-136550T","-136551C","-136552A","-136553T","-136554C","C164210T","-174531G","-174532A","-174533T","-174534G","-174535A","-174536A"],"OPG153":["-381D","-382D","-383D","-384D","-385D"],"OPG189":["S293L"]},"labels":{"aa":"OPG153: -381D, -382D, -383D, -384D, -385D; OPG189: S293L"}}},{"name":"OP605572","node_attrs":{"div":39,"accession":"OP605572","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"lineage":{"value":"A.2.1"},"strain":{"value":"Slovenia-MPXV-30-2022"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Slovenia/OP605572/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C165-","A196625-","T196626-","T196627-"]}}}]}]}]}]}]}]},{"name":"NODE_0000021","node_attrs":{"div":6,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["A173314-","T173315-","A173316-","T173317-","C187428T"]}},"children":[{"name":"NODE_0000022","node_attrs":{"div":14,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["G56968A","G61844A","C84008T","G96841A","C100971T","C134078T","C151050T","G188889-"],"OPG074":["S53L"],"OPG117":["D265N"],"OPG120":["E260K"]},"labels":{"aa":"OPG074: S53L; OPG117: D265N; OPG120: E260K","clade":"A.3"}},"children":[{"name":"MG693723","node_attrs":{"div":27,"accession":"MG693723","author":{"author":"Faye,O.,Pratt,C.B.,Faye,M.,Fall,G.,Chitty,J.A.,Diagne,M.M.,Wiley,M.R.,Yinka-Ogunleye,A.F.,Aruna,S.,Etebu,E.N.,Aworabhi,N.,Ogoina,D.,Numbere,W.,Mba,N.,Palacios,G.,Sall,A.A.,Ihekweazu,C.,Diagne,M.,Palacios,G.F.,Sall,A.","value":"Faye,O.,Pratt,C.B.,Faye,M.,Fall,G.,Chitty,J.A.,Diagne,M.M.,Wiley,M.R.,Yinka-Ogunleye,A.F.,Aruna,S.,Etebu,E.N.,Aworabhi,N.,Ogoina,D.,Numbere,W.,Mba,N.,Palacios,G.,Sall,A.A.,Ihekweazu,C.,Diagne,M.,Palacios,G.F.,Sall,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"USAMRIID, Center for Genome Sciences"},"lineage":{"value":"A.3"},"strain":{"value":"MPXV_Nig_2017_297957"},"date":{"value":"2017-XX-XX"},"strain_display":{"value":"Nigeria/MG693723/2017-XX-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A8143-","G8144-","C8145-","A8146-","T8147-","A8148-","T8149-","T8150-","A8151-","A8152-","A8153-","G8154-","T8155-","A8156-","A8157-","A8158-","A8159-","T8160-","C8161-","T8162-","A8163-","G8164-","T8165-","T8166-","A8167-","C8168-","C8169-","T8170-","T8171-","G8172-","A8173-","A8174-","A8175-","A8176-","T8177-","G8178-","A8179-","A8180-","T8181-","A8182-","C8183-","A8184-","G8185-","T8186-","G8187-","G8188-","G8189-","T8190-","G8191-","G8192-","T8193-","T8194-","C8195-","C8196-","G8197-","T8198-","A8199-","T8200-","C8201-","A8202-","C8203-","C8204-","A8205-","G8206-","T8207-","A8208-","A8209-","G8210-","A8211-","A8212-","C8213-","A8214-","T8215-","A8216-","A8217-","T8218-","A8219-","G8220-","T8221-","C8222-","G8223-","A8224-","A8225-","T8226-","A8227-","C8228-","A8229-","G8230-","T8231-","A8232-","T8233-","C8234-","C8235-","G8236-","A8237-","T8238-","T8239-","G8240-","A8241-","G8242-","A8243-","T8244-","T8245-","T8246-","T8247-","G8248-","C8249-","A8250-","T8251-","A8252-","C8253-","A8254-","A8255-","T8256-","A8257-","C8258-","T8259-","A8260-","G8261-","T8262-","C8263-","T8264-","A8265-","G8266-","A8267-","A8268-","A8269-","G8270-","A8271-","A8272-","A8273-","T8274-","T8275-","T8276-","G8277-","T8278-","A8279-","A8280-","T8281-","C8282-","A8283-","T8284-","C8285-","C8286-","T8287-","C8288-","T8289-","G8290-","T8291-","G8292-","A8293-","C8294-","A8295-","G8296-","G8297-","A8298-","G8299-","T8300-","C8301-","C8302-","A8303-","T8304-","A8305-","T8306-","A8307-","T8308-","C8309-","T8310-","G8311-","T8312-","A8313-","T8314-","C8315-","A8316-","T8317-","C8318-","G8319-","T8320-","C8321-","T8322-","A8323-","G8324-","T8325-","T8326-","T8327-","T8328-","T8329-","A8330-","T8331-","C8332-","A8333-","G8334-","T8335-","G8336-","T8337-","C8338-","C8339-","T8340-","A8341-","T8342-","G8343-","C8344-","T8345-","A8346-","T8347-","A8348-","T8349-","T8350-","C8351-","C8352-","T8353-","G8354-","T8355-","T8356-","A8357-","T8358-","C8359-","A8360-","T8361-","C8362-","A8363-","T8364-","T8365-","A8366-","G8367-","T8368-","T8369-","A8370-","A8371-","T8372-","G8373-","A8374-","A8375-","A8376-","A8377-","T8378-","A8379-","A8380-","C8381-","T8382-","C8383-","T8384-","C8385-","G8386-","T8387-","G8388-","C8389-","T8390-","T8391-","C8392-","A8393-","G8394-","A8395-","A8396-","A8397-","A8398-","G8399-","T8400-","C8401-","A8402-","A8403-","A8404-","T8405-","A8406-","T8407-","T8408-","G8409-","T8410-","A8411-","T8412-","C8413-","C8414-","A8415-","T8416-","A8417-","C8418-","A8419-","T8420-","A8421-","T8422-","A8423-","T8424-","C8425-","T8426-","C8427-","C8428-","A8429-","A8430-","A8431-","A8432-","C8433-","T8434-","A8435-","T8436-","C8437-","A8438-","C8439-","T8440-","T8441-","A8442-","T8443-","A8444-","C8445-","G8446-","T8447-","T8448-","T8449-","A8450-","T8451-","C8452-","T8453-","T8454-","T8455-","A8456-","A8457-","C8458-","G8459-","A8460-","A8461-","C8462-","A8463-","T8464-","A8465-","T8466-","A8467-","C8468-","C8469-","T8470-","A8471-","G8472-","A8473-","T8474-","G8475-","G8476-","T8477-","T8478-","A8479-","T8480-","T8481-","T8482-","A8483-","C8484-","T8485-","A8486-","A8487-","C8488-","A8489-","G8490-","A8491-","C8492-","A8493-","T8494-","T8495-","T8496-","T8497-","T8498-","T8499-","C8500-","A8501-","A8502-","G8503-","A8504-","T8505-","C8506-","T8507-","A8508-","T8509-","T8510-","G8511-","A8512-","C8513-","A8514-","A8515-","T8516-","A8517-","A8518-","C8519-","T8520-","C8521-","C8522-","T8523-","A8524-","T8525-","A8526-","G8527-","T8528-","T8529-","T8530-","C8531-","C8532-","A8533-","C8534-","A8535-","T8536-","C8537-","A8538-","A8539-","C8540-","C8541-","A8542-","A8543-","G8544-","T8545-","A8546-","A8547-","T8548-","G8549-","A8550-","T8551-","C8552-","A8553-","T8554-","C8555-","T8556-","A8557-","T8558-","T8559-","G8560-","T8561-","T8562-","A8563-","T8564-","A8565-","T8566-","A8567-","A8568-","C8569-","A8570-","A8571-","T8572-","A8573-","A8574-","C8575-","A8576-","T8577-","A8578-","A8579-","C8580-","T8581-","C8582-","T8583-","T8584-","T8585-","T8586-","C8587-","C8588-","A8589-","T8590-","T8591-","T8592-","T8593-","T8594-","A8595-","T8596-","C8597-","A8598-","G8599-","T8600-","A8601-","T8602-","C8603-","T8604-","A8605-","T8606-","A8607-","T8608-","C8609-","A8610-","A8611-","C8612-","G8613-","T8614-","C8615-","G8616-","T8617-","T8618-","G8619-","T8620-","A8621-","G8622-","T8623-","G8624-","A8625-","A8626-","T8627-","A8628-","G8629-","T8630-","A8631-","G8632-","T8633-","C8634-","A8635-","T8636-","T8637-","G8638-","A8639-","T8640-","C8641-","T8642-","A8643-","T8644-","T8645-","A8646-","T8647-","A8648-","T8649-","G8650-","A8651-","A8652-","A8653-","C8654-","G8655-","G8656-","A8657-","T8658-","A8659-","T8660-","G8661-","T8662-","C8663-","T8664-","A8665-","G8666-","T8667-","T8668-","A8669-","A8670-","T8671-","A8672-","T8673-","T8674-","T8675-","T8676-","C8677-","T8678-","T8679-","T8680-","G8681-","A8682-","T8683-","T8684-","T8685-","A8686-","A8687-","A8688-","G8689-","T8690-","C8691-","T8692-","A8693-","T8694-","A8695-","G8696-","T8697-","C8698-","T8699-","T8700-","T8701-","A8702-","C8703-","A8704-","A8705-","A8706-","C8707-","A8708-","T8709-","A8710-","A8711-","T8712-","A8713-","T8714-","C8715-","C8716-","T8717-","T8718-","A8719-","T8720-","C8721-","C8722-","G8723-","A8724-","C8725-","T8726-","T8727-","T8728-","A8729-","T8730-","A8731-","T8732-","T8733-","T8734-","C8735-","C8736-","T8737-","G8738-","T8739-","A8740-","G8741-","G8742-","G8743-","T8744-","G8745-","G8746-","C8747-","A8748-","T8749-","A8750-","A8751-","T8752-","T8753-","T8754-","T8755-","A8756-","T8757-","T8758-","C8759-","T8760-","G8761-","C8762-","C8763-","T8764-","C8765-","C8766-","A8767-","C8768-","A8769-","A8770-","T8771-","C8772-","A8773-","G8774-","T8775-","G8776-","T8777-","T8778-","T8779-","C8780-","C8781-","A8782-","A8783-","A8784-","T8785-","A8786-","T8787-","A8788-","T8789-","T8790-","A8791-","C8792-","T8793-","A8794-","G8795-","A8796-","C8797-","A8798-","A8799-","T8800-","A8801-","T8802-","T8803-","C8804-","C8805-","A8806-","T8807-","A8808-","T8809-","A8810-","G8811-","T8812-","T8813-","A8814-","T8815-","T8816-","A8817-","G8818-","T8819-","T8820-","A8821-","A8822-","G8823-","G8824-","G8825-","A8826-","C8827-","C8828-","C8829-","A8830-","A8831-","T8832-","T8833-","A8834-","G8835-","A8836-","A8837-","C8838-","A8839-","C8840-","G8841-","T8842-","A8843-","C8844-","G8845-","C8846-","G8847-","C8848-","T8849-","T8850-","A8851-","T8852-","T8853-","C8854-","A8855-","T8856-","C8857-","A8858-","T8859-","T8860-","T8861-","G8862-","G8863-","A8864-","T8865-","C8866-","G8867-","T8868-","A8869-","T8870-","T8871-","T8872-","C8873-","A8874-","T8875-","A8876-","A8877-","A8878-","A8879-","G8880-","T8881-","T8882-","A8883-","T8884-","T8885-","A8886-","T8887-","G8888-","T8889-","T8890-","A8891-","T8892-","A8893-","G8894-","A8895-","T8896-","G8897-","T8898-","C8899-","A8900-","A8901-","C8902-","A8903-","C8904-","A8905-","T8906-","T8907-","C8908-","T8909-","A8910-","C8911-","A8912-","T8913-","T8914-","T8915-","T8916-","T8917-","T8918-","T8919-","A8920-","A8921-","T8922-","T8923-","G8924-","T8925-","C8926-","T8927-","A8928-","T8929-","A8930-","T8931-","A8932-","G8933-","T8934-","A8935-","T8936-","T8937-","T8938-","T8939-","T8940-","C8941-","T8942-","G8943-","A8944-","T8945-","A8946-","T8947-","T8948-","T8949-","T8950-","C8951-","T8952-","A8953-","T8954-","A8955-","A8956-","T8957-","A8958-","T8959-","C8960-","A8961-","G8962-","A8963-","A8964-","T8965-","T8966-","G8967-","T8968-","C8969-","T8970-","T8971-","C8972-","C8973-","A8974-","T8975-","A8976-","G8977-","G8978-","A8979-","A8980-","G8981-","T8982-","T8983-","G8984-","T8985-","A8986-","T8987-","A8988-","C8989-","T8990-","A8991-","T8992-","T8993-","C8994-","G8995-","G8996-","A8997-","A8998-","T8999-","C9000-","A9001-","G9002-","T9003-","T9004-","A9005-","C9006-","A9007-","T9008-","G9009-","T9010-","T9011-","T9012-","A9013-","A9014-","A9015-","T9016-","A9017-","A9018-","T9019-","T9020-","C9021-","T9022-","C9023-","T9024-","G9025-","A9026-","T9027-","G9028-","T9029-","C9030-","A9031-","T9032-","T9033-","C9034-","C9035-","T9036-","T9037-","A9038-","T9039-","A9040-","C9041-","A9042-","A9043-","T9044-","C9045-","A9046-","A9047-","A9048-","T9049-","T9050-","C9051-","A9052-","T9053-","T9054-","A9055-","T9056-","T9057-","A9058-","A9059-","A9060-","C9061-","A9062-","G9063-","T9064-","T9065-","T9066-","A9067-","A9068-","T9069-","A9070-","G9071-","T9072-","C9073-","T9074-","G9075-","T9076-","A9077-","G9078-","A9079-","C9080-","C9081-","T9082-","T9083-","T9084-","A9085-","T9086-","C9087-","G9088-","T9089-","C9090-","G9091-","T9092-","A9093-","C9094-","A9095-","T9096-","A9097-","T9098-","C9099-","C9100-","A9101-","T9102-","T9103-","G9104-","T9105-","C9106-","T9107-","T9108-","A9109-","T9110-","T9111-","A9112-","G9113-","T9114-","T9115-","A9116-","C9117-","G9118-","C9119-","T9120-","T9121-","A9122-","T9123-","T9124-","T9125-","T9126-","T9127-","A9128-","T9129-","G9130-","G9131-","G9132-","T9133-","T9134-","T9135-","T9136-","A9137-","C9138-","G9139-","T9140-","T9141-","G9142-","C9143-","T9144-","T9145-","T9146-","A9147-","T9148-","T9149-","A9150-","T9151-","A9152-","T9153-","T9154-","T9155-","T9156-","A9157-","T9158-","A9159-","A9160-","T9161-","A9162-","A9163-","T9164-","G9165-","A9166-","T9167-","T9168-","G9169-","T9170-","T9171-","T9172-","G9173-","A9174-","C9175-","A9176-","A9177-","T9178-","G9179-","T9180-","C9181-","G9182-","T9183-","A9184-","G9185-","T9186-","A9187-","T9188-","A9189-","G9190-","A9191-","T9192-","A9193-","T9194-","A9195-","T9196-","T9197-","A9198-","T9199-","T9200-","A9201-","G9202-","A9203-","G9204-","G9205-","A9206-","G9207-","G9208-","T9209-","A9210-","T9211-","A9212-","A9213-","T9214-","T9215-","A9216-","T9217-","A9218-","A9219-","A9220-","A9221-","A9222-","G9223-","T9224-","T9225-","T9226-","C9227-","T9228-","G9229-","A9230-","G9231-","T9232-","A9233-","C9234-","G9235-","A9236-","T9237-","G9238-","T9239-","T9240-","A9241-","T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","C9257-","A9258-","T9259-","T9260-","A9261-","A9262-","C9263-","A9264-","T9265-","C53702T","-146895T","-146897T","-146898T","-146899T","-146900T","-146902T","-146903T","-146904T","-146905T","-146907T","-146909T","-146910T","-146911T","-146912T","A166866-","C166867-","T166868-","G166869-","A166870-","T166871-","G166872-","A166873-","T166874-","A166875-","A166876-","T166877-","A166878-","A166879-","T166880-","G166881-","A166882-","A166883-","T166884-","T166885-","G166886-","G166887-","T166888-","G166889-","T166890-","T166891-","A166892-","A166893-","A166894-","T166895-","T166896-","T166897-","T166898-","A166899-","A166900-","A166901-","G166902-","A166903-","G166904-","T166905-","A166906-","C166907-","A166908-","C166909-","A166910-","A166911-","T166912-","T166913-","T166914-","C166915-","T166916-","A166917-","T166918-","T166919-","A166920-","T166921-","T166922-","A166923-","C166924-","A166925-","G166926-","A166927-","G166928-","T166929-","C166930-","A166931-","T166932-","G166933-","T166934-","G166935-","A166936-","C166937-","G166938-","T166939-","C166940-","G166941-","G166942-","A166943-","T166944-","T166945-","T166946-","G166947-","A166948-","T166949-","T166950-","C166951-","C166952-","A166953-","T166954-","A166955-","G166956-","A166957-","T166958-","A166959-","T166960-","A166961-","G166962-","A166963-","T166964-","G166965-","T166966-","T166967-","A166968-","T166969-","A166970-","A166971-","A166972-","C166973-","G166974-","A166975-","C166976-","T166977-","A166978-","T166979-","A166980-","A166981-","A166982-","A166983-","T166984-","T166985-","A166986-","T166987-","T166988-","G166989-","A166990-","T166991-","A166992-","T166993-","G166994-","T166995-","A166996-","T166997-","A166998-","C166999-","C168582A","C168584-","T168585-","C168586-","T168587-","G168588-","T168589-","A168590-","T168591-","T168592-","T168593-","C168594-","T168595-","G168596-","T168597-","A168598-","T168599-","A168600-","T168601-","T168602-","G168603-","T168604-","G168605-","A168606-","T168607-","C168608-","A168609-","A168610-","G168611-","A168612-","G168613-","G168614-","C168615-","G168616-","G168617-","G168618-","A168619-","G168620-","T168624G","A168626-","A168627-","A168628-","T168629-","T168630-","T168631-","G168632-","A168633-","G168634-","G168635-","A168636-","G168637-","T168638-","A168639-","T168640-","A168641-","C168642-","T168643-","C168644-","A168645-","A168646-","G168647-","A168648-","A168649-","T168650-","C168651-","A168652-","A168653-","G168654-","T168655-","G168656-","A168657-","T168658-","A168659-","T168660-","C168661-","A168662-","G168663-","T168664-","A168665-","T168666-","T168667-","A168668-","A168674-","A168675-","G168676-","T168677-","A168678-","T168679-","G168680-","A168681-","T168682-","T168683-","C168684-","A168685-","T168686-","C168687-","A168688-","T168689-","G168690-","T168691-","A168692-","T168693-","T168694-","G168695-","A168696-","T168697-","T168698-","A168699-","T168700-","G168704-","G168705-","T168706-","A168707-","T168708-","T168709-","A168710-","A168711-","T168712-","C168713-","A168714-","A168715-","A168716-","G168717-","T168718-","T168719-","T168720-","C168721-","A168722-","T168723-","G168724-","A168725-","A168726-","T168727-","T168731C","G168732A","A168734T","C168737G","G168741-","A168742-","A168743-","T168744-","A168748T","C168750G","G168755-","A168756-","T168757-","A168758-","G168759-","A168760-","G168761-","A168762-","A168763-","T168764-","C168765-","A168766-","T168767-","G168768-","C168769-","G168770-","T168771-","C168772-","A168773-","G168774-","A168775-","T168777G","C169569-","A169570-","T169571-","T169572-","T169573-","A169574-","A169575-","T169576-","A169577-","A169578-","G169579-","G169580-","A169581-","C169582-","A169583-","T169584-","T169585-","G169586-","G169587-","A169588-","T169589-","A169590-","T169591-","G169592-","T169593-","G169594-","G169595-","A169596-","A169597-","A169598-","A169599-","G169600-","T169601-","G169602-","A169603-","T169604-","G169605-","T169606-","A169607-","T169608-","G169609-","G169610-","A169611-","A169612-","G169613-","T169614-","T169615-","A169616-","G169617-","T169618-","A169619-","C169620-","A169621-","T169622-","T169623-","A169624-","T169625-","C169626-","A169627-","A169628-","C169629-","T169630-","T169631-","C169632-","T169633-","C169634-","C169635-","T169636-","T169637-","A169638-","T169639-","T169640-","G169641-","A169642-","T169643-","T169644-","G169645-","A169646-","A169647-","A169648-","A169649-","T169650-","G169651-","A169652-","A169653-","A169654-","A169655-","T169656-","A169657-","T169658-","A169659-","A169660-","A169661-","T169662-","A169663-","G169664-","T169665-","T169666-","T169667-","T169668-","T169669-","A169670-","T169671-","G169672-","T169673-","A169674-","T169675-","A169676-","G169677-","C169678-","G169679-","G169680-","T169681-","A169682-","T169683-","C169684-","T169685-","A169686-","C169687-","C169688-","C169689-","T169690-","A169691-","T169692-","A169693-","G169694-","T169695-","T169696-","T169697-","T169698-","A169699-","T169700-","T169701-","G169702-","C169703-","T169704-","T169705-","A169706-","C169707-","T169708-","A169709-","C169710-","T169711-","A169712-","A169713-","C169714-","A169715-","T169716-","G169717-","G169718-","A169719-","T169720-","T169721-","C169722-","A169723-","G169724-","A169725-","T169726-","A169727-","C169728-","A169729-","G169730-","A169731-","T169732-","A169733-","C169734-","A169735-","G169736-","A169737-","T169738-","A169739-","C169740-","A169741-","G169742-","A169743-","T169744-","A169745-","C169746-","A169747-","G169748-","A169749-","T169750-","A169751-","C169752-","A169753-","G169754-","A169755-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","T187263G","A187265-","G187266-","A187267-","A187268-","T187269-","C187270-","A187271-","T187272-","T187273-","T187274-","A187275-","T187276-","C187277-","A187278-","T187279-","A187280-","A187281-","C187282-","T187283-","A187284-","T187285-","G187286-","T187287-","T187288-","T187289-","A187290-","A187291-","T187292-","A187293-","A187294-","A187295-","T187296-","T187297-","C187298-","A187299-","T187300-","C187301-","A187302-","A187303-","C187304-","G187305-","A187306-","A187307-","T187308-","A187309-","T187310-","C187311-","G187312-","A187313-","T187314-","A187315-","A187316-","A187317-","G187318-","A187319-","C187320-","C187321-","T187322-","C187323-","T187324-","T187325-","G187326-","T187327-","A187328-","A187329-","T187330-","T187331-","C187332-","G187333-","A187334-","G187335-","T187336-","A187337-","T187338-","A187339-","G187340-","G187341-","A187342-","A187343-","G187344-","T187345-","A187346-","G187347-","T187348-","A187349-","T187350-","T187351-","A187352-","C187353-","C187354-","A187355-","T187356-","A187357-","T187358-","C187359-","A187360-","A187361-","C187362-","C187366T","A187372-","A187373-","C187374-","A187375-","A187376-","T187377-","T187378-","A187379-","C187380-","T187381-","C187382-","T187383-","A187384-","A187385-","A187386-","A187387-","C187388-","A187389-","T187390-","G187391-","A187392-","G187393-","G187394-","A187395-","T187396-","T187397-","G187398-","T187399-","A187400-","C187401-","T187402-","C187403-","C187404-","T187405-","G187406-","T187407-","C187408-","T187409-","T187410-","G187415-","G187416-","A187417-","G187418-","A187419-","T187420-","C187421-","A187422-","C187423-","T187424-","A187425-","T187426-","T187427-","T187428-","A187429-","G187430-","T187431-","C187432-","G187433-","T187434-","T187435-","G187436-","A187437-","T187438-","A187439-","A187440-","A187441-","C187442-","T187443-","A187444-","G187445-","T187446-","A187447-","A187448-","C187449-","C187450-","T187451-","C187452-","A187453-","G187454-","G187455-","T187456-","T187457-","T187458-","C187459-","T187460-","T187461-","T187462-","A187463-","C187464-","A187465-","A187466-","A187467-","C187468-","G187469-","A187470-","T187471-","A187472-","A187473-","A187474-","G187475-","T187476-","A187477-","C187478-","A187479-","A187480-","C187481-","A187482-","T187483-","C187484-","A187485-","A187486-","G187487-","A187488-","C187489-","C187490-","T187491-","C187492-","A187493-","C187494-","A187495-","A187496-","C187497-","A187498-","C187499-","A187500-","G187501-","T187502-","G187503-","C187504-","A187505-","A187506-","G187507-","A187508-","T187509-","T187510-","A187511-","A187512-","T187513-","C187514-","T187515-","A187516-","G187517-","A187518-","A187519-","A187520-","T187521-","C187522-","A187523-","A187524-","A187525-","T187526-","G187527-","T187528-","A187529-","A187530-","T187531-","T187532-","C187533-","T187534-","G187535-","G187536-","A187537-","G187538-","G187539-","C187545-","T187546-","A187547-","G187548-","A187549-","C187550-","A187551-","A187552-","C187553-","T187554-","A187555-","A187556-","C187557-","A187558-","C187559-","C187560-","C187561-","A187562-","C187563-","G187564-","G187565-","C187566-","G187567-","A187568-","A187569-","G187570-","T187571-","A187572-","T187573-","A187574-","C187575-","T187576-","T187577-","T187578-","A187579-","T187580-","G187581-","C187582-","C187583-","T187584-","C187585-","A187586-","T187587-","T187588-","C187589-","A187590-","G187591-","A187592-","A187593-","A187594-","C187595-","G187596-","G187597-","T187598-","A187599-","A187600-","C187601-","T187602-","G187603-","T187604-","A187605-","G187606-","T187607-","A187608-","G187609-","G187610-","A187611-","G187612-","A187613-","C187614-","T187615-","G187616-","T187617-","C187618-","T187619-","C187620-","T187621-","C187622-","T187623-","A187624-","A187625-","T187626-","C187627-","T187628-","C187629-","G187630-","A187631-","T187632-","G187633-","T187634-","A187635-","T187636-","A187637-","T187638-","A187639-","T187640-","A187641-","A187642-","T187643-","A187644-","T187645-","A187646-","T187647-","A187648-","C187649-","C187650-","A187651-","A187652-","T187653-","A187654-","C187655-","G187656-","G187657-","A187658-","C187659-","G187660-","C187661-","G187662-","A187663-","T187664-","A187665-","T187666-","A187667-","T187668-","T187669-","C187670-","C187671-","G187672-","A187673-","C187674-","A187675-","T187676-","G187677-","A187678-","A187679-","T187680-","G187681-","G187682-","C187683-","G187684-","T187685-","C187686-","G187687-","C187688-","T187689-","T187690-","A187691-","T187692-","C187693-","A187694-","T187695-","A187696-","T187697-","G187698-","T187699-","T187700-","A187701-","T187702-","A187703-","T187704-","C187705-","C187706-","T187707-","A187708-","A187709-","A187710-","T187711-","G187712-","T187713-","T187714-","G187715-","A187716-","T187717-","C187718-","A187719-","T187720-","A187721-","T187722-","T187723-","C187724-","C187725-","A187726-","C187727-","A187728-","A187729-","A187730-","T187731-","G187732-","A187733-","T187734-","T187735-","G187736-","T187737-","G187738-","A187739-","A187740-","C187741-","G187742-","A187743-","G187744-","A187745-","T187746-","T187747-","A187748-","A187749-","A187750-","T187751-","C187752-","A187753-","T187754-","C187755-","T187756-","A187757-","A187758-","C187759-","A187760-","A187761-","A187762-","T187763-","A187764-","A187765-","T187766-","T187767-","A187768-","G187769-","T187770-","T187771-","T187772-","T187773-","T187774-","T187775-","A187776-","T187777-","G187778-","A187779-","C187780-","A187781-","T187782-","T187783-","A187784-","A187785-","C187786-","A187787-","T187788-","A187789-","T187790-","A187791-","A187792-","T187793-","A187794-","A187795-","A187796-","T187797-","A187798-","A187799-","A187800-","T187801-","T187802-","A187803-","A187804-","T187805-","C187806-","A187807-","T187808-","T187809-","A187810-","T187811-","T187812-","G187813-","A187814-","C187815-","T187816-","T187817-","A187818-","A187819-","C187820-","G187821-","A187822-","T187823-","G187824-","A187825-","C187826-","G187827-","A187828-","A187829-","A187830-","G187831-","T187832-","T187833-","A187834-","T187835-","C187836-","A187837-","T187838-","T187839-","A187840-","T187841-","C187842-","T187843-","T187844-","A187845-","G187846-","G187847-","A187848-","T187849-","T187850-","C187851-","T187852-","T187853-","G187854-","A187855-","T187856-","T187857-","A187858-","T187859-","T187860-","A187861-","A187862-","T187863-","A187864-","C187865-","A187866-","A187867-","A187868-","T187869-","T187870-","C187871-","G187872-","T187873-","T187874-","T188117-","T188118-","A188119-","T188120-","C188121-","G188122-","T188123-","C188124-","T188125-","C188126-","C188127-","T188128-","T188129-","A188130-","A188131-","A188132-","G188133-","C188134-","T188135-","T188136-","C188137-","T188138-","G188139-","A188140-","T188141-","G188142-","G188143-","T188144-","A188145-","A188146-","C188147-","T188148-","G188149-","T188150-","G188151-","T188152-","T188153-","A188154-","C188155-","A188156-","T188157-","G188158-","T188159-","G188160-","C188161-","T188162-","C188163-","C188164-","T188165-","A188166-","A188167-","A188168-","A188169-","C188170-","A188171-","A188172-","A188173-","A188174-","T188175-","A188176-","T188177-","G188178-","G188179-","T188180-","C188181-","G188182-","T188183-","G188184-","T188185-","G188186-","T188187-","A188188-","C188189-","G188190-","G188191-","A188192-","A188193-","A188194-","G188195-","A188196-","A188197-","A188198-","G188199-","G188200-","A188201-","G188202-","A188203-","A188204-","A188205-","A188206-","T188207-","G188208-","A188209-","T188210-","A188211-","T188212-","G188213-","G188214-","A188215-","A188216-","T188217-","A188218-","C188219-","C188220-","A188221-","T188222-","T188223-","T188224-","G188225-","T188226-","A188227-","A188228-","G188229-","A188230-","A188231-","A188232-","T188233-","G188234-","T188235-","C188236-","G188237-","G188238-","A188239-","A188240-","G188241-","G188242-","G188243-","T188244-","A188245-","C188246-","T188247-","T188248-","A188249-","T188250-","T188251-","C188252-","A188253-","G188254-","A188255-","T188256-","A188257-","T188258-","T188259-","G188260-","T188261-","A188262-","T188263-","C188264-","T188265-","G188266-","A188267-","C188268-","T188269-","C188270-","T188271-","G188272-","A188273-","T188274-","C188275-","A188276-","A188277-","T188278-","G188279-","T188280-","A188281-","A188282-","A188283-","C188284-","C188285-","T188286-","A188287-","T188288-","G188289-","A188290-","C188291-","A188292-","A188293-","G188294-","A188295-","T188296-","A188297-","A188298-","G188299-","A188300-","C188301-","T188302-","T188303-","A188304-","C188305-","T188306-","C188307-","G188308-","C188309-","A188310-","T188311-","C188312-","T188313-","A188314-","C188315-","T188316-","G188317-","G188318-","A188319-","T188320-","A188321-","G188322-","A188323-","C188324-","A188325-","T188326-","A188327-","A188328-","A188329-","T188330-","A188331-","T188332-","C188333-","C188334-","T188335-","C188336-","C188337-","T188338-","C188339-","G188340-","T188341-","A188342-","A188343-","T188344-","A188345-","A188346-","T188347-","G188348-","A188349-","A188350-","A188351-","T188352-","A188353-","T188354-","A188355-","A188356-","T188357-","A188358-","T188359-","A188360-","C188361-","A188362-","C188363-","T188364-","A188365-","A188366-","T188367-","T188368-","A188369-","T188370-","T188371-","A188372-","A188373-","T188374-","A188375-","T188376-","C188377-","A188378-","A188379-","T188380-","C188381-","G188382-","A188383-","G188384-","T188385-","A188386-","T188387-","T188388-","A188389-","A188390-","C188391-","A188392-","T188393-","A188394-","T188395-","A188396-","A188397-","G188398-","T188399-","T188400-","A188401-","T188402-","T188403-","T188404-","T188405-","T188406-","A188407-","A188408-","A188409-","C188410-","C188411-","C188412-","C188413-","T188414-","T188415-","T188416-","T188417-","G188418-","G188419-","G188420-","T188421-","T188422-","C188423-","C188424-","G188425-","T188426-","C188427-","C188428-","T188429-","A188430-","A188431-","A188432-","C188433-","G188434-","G188435-","C188436-","G188437-","T188438-","T188439-","T188440-","C188441-","G188442-","G188443-","T188444-","C188445-","T188446-","G188447-","T188448-","G188449-","T188450-","C188451-","G188452-","C188453-","C188454-","A188455-","C188456-","C188457-","A188458-","T188459-","G188460-","G188461-","T188462-","C188463-","A188464-","C188465-","A188466-","C188467-","C188468-","G188469-","A188470-","G188471-","C188472-","C188473-","T188474-","C188475-","T188476-","G188477-","C188478-","G188479-","T188480-","G188481-","C188482-","T188483-","C188484-","C188485-","T188486-","C188487-","C188488-","A188489-","T188490-","C188491-","G188492-","A188493-","G188494-","G188495-","A188496-","C188497-","G188498-","A188499-","C188500-","T188501-","T188502-","C188503-","A188504-","A188505-","C188506-","T188507-","A188508-","T188509-","G188510-","A188511-","C188512-","A188513-","G188514-","C188515-","T188516-","C188517-","G188518-","G188519-","T188520-","G188521-","G188522-","C188523-","G188524-","T188525-","C188526-","T188527-","G188528-","C188529-","C188530-","A188531-","G188532-","C188533-","G188534-","T188535-","G188536-","T188537-","A188538-","C188539-","A188540-","T188541-","A188542-","C188543-","G188544-","A188545-","A188546-","T188547-","G188548-","G188549-","C188550-","A188551-","T188552-","T188553-","T188554-","C188555-","T188556-","A188557-","A188558-","G188559-","A188560-","A188561-","A188562-","A188563-","G188564-","T188565-","C188566-","T188567-","A188568-","C188569-","G188570-","G188571-","T188572-","A188573-","T188574-","C188575-","C188576-","T188577-","T188578-","T188579-","C188580-","T188581-","A188582-","C188583-","A188584-","A188585-","T188586-","T188587-","T188588-","C188589-","C188590-","T188591-","T188592-","T188593-","A188594-","A188595-","C188596-","A188597-","A188598-","C188599-","G188600-","G188601-","C188602-","A188603-","A188604-","C188605-","A188606-","G188607-","C188608-","T188609-","G188610-","C188611-","A188612-","G188613-","T188614-","A188615-","T188616-","T188617-","T188618-","T188619-","T188620-","A188621-","T188622-","A188623-","C188624-","T188625-","T188626-","T188627-","G188628-","A188629-","A188630-","T188631-","G188632-","C188633-","A188634-","T188635-","C188636-","G188637-","G188638-","A188639-","C188640-","A188641-","T188642-","T188643-","T188644-","A188645-","T188646-","A188647-","C188648-","A188649-","A188650-","G188651-","G188652-","G188653-","A188654-","G188655-","T188656-","C188657-","C188658-","T188659-","G188660-","T188661-","T188662-","C188663-","T188664-","A188665-","A188666-","T188667-","A188668-","T188669-","T188670-","G188671-","G188672-","C188673-","A188674-","T188675-","C188676-","A188677-","A188678-","T188679-","G188680-","T188681-","T188682-","C188683-","G188684-","G188685-","A188686-","T188687-","C188688-","T188689-","A188690-","T188691-","A188692-","G188693-","G188694-","C188695-","T188696-","T188697-","G188698-","A188699-","T188700-","T188701-","T188702-","T188703-","C188704-","G188705-","C188706-","A188707-","T188708-","T188709-","G188710-","A188711-","C188712-","T188713-","T188714-","T188715-","A188716-","C188717-","A188718-","C188719-","A188720-","G188721-","A188722-","C188723-","A188724-","T188725-","G188726-","A188727-","A188728-","C188729-","A188730-","T188731-","C188732-","C188733-","C188734-","C188735-","T188736-","G188737-","A188738-","A188739-","T188740-","C188741-","T188742-","G188743-","T188744-","A188745-","C188746-","A188747-","T188748-","A188749-","C188750-","T188751-","T188752-","T188753-","G188754-","T188755-","G188756-","G188757-","A188758-","T188759-","T188760-","T188761-","A188762-","C188763-","A188764-","C188765-","T188766-","G188767-","T188768-","T188769-","A188770-","G188771-","A188772-","A188773-","T188774-","C188775-","T188776-","C188777-","T188778-","A188779-","A188780-","C188781-","G188782-","C188783-","T188784-","G188785-","G188786-","C188787-","C188788-","T188789-","C188790-","T188791-","G188792-","T188793-","T188794-","G188795-","T188796-","T188797-","A188798-","C188799-","T188800-","T188801-","T188802-","C188803-","T188804-","A188805-","T188806-","G188807-","A188808-","T188809-","G188810-","C188811-","A188812-","C188813-","G188814-","T188815-","A188816-","T188817-","C188818-","G188819-","T188820-","T188821-","A188822-","T188823-","G188824-","C188825-","A188826-","A188827-","G188828-","C188829-","T188830-","T188831-","T188832-","C188833-","A188834-","T188835-","G188836-","T188837-","T188838-","G188839-","A188840-","C188841-","T188842-","A188843-","C188844-","T188845-","G188846-","C188847-","A188848-","G188849-","T188850-","G188851-","T188852-","T188853-","T188854-","C188855-","T188856-","T188857-","G188858-","C188859-","T188860-","C188861-","T188862-","G188863-","A188864-","C188865-","T188866-","A188867-","C188868-","A188869-","T188870-","A188871-","T188872-","A188873-","C188874-","T188875-","C188876-","T188877-","A188878-","C188879-","A188880-","A188881-","T188882-","C188883-","A188884-","A188885-","A188886-","G188887-","A188888-","A188890-","G188891-","A188892-","T188893-","T188894-","T188895-","C188896-","A188897-","G188898-","T188899-","A188900-","A188901-","A188902-","C188903-","T188904-","T188905-","G188906-","T188907-","A188908-","A188909-","C188910-","A188911-","G188912-","G188913-","A188914-","T188915-","T188916-","G188917-","T188918-","T188919-","T188920-","G188921-","C188922-","T188923-","G188924-","C188925-","T188926-","T188927-","T188928-","C188929-","T188930-","G188931-","G188932-","A188933-","T188934-","T188935-","T188936-","T188937-","A188938-","A188939-","T188940-","T188941-","T188942-","T188943-","G188944-","T188945-","C188946-","A188947-","G188948-","G188949-","A188950-","G188951-","T188952-","C188953-","T188954-","T188955-","G188956-","A188957-","G188958-","G188959-","A188960-","T188961-","A188962-","A188963-","A188964-","G188965-","T188966-","T188967-","T188968-","A188969-","A188970-","A188971-","A188972-","T188973-","A188974-","G188975-","A188976-","A188977-","T188978-","T188979-","A188980-","A188981-","T188982-","A188983-","A188984-","A188985-","G188986-","A188987-","A188988-","C188989-","A188990-","T188991-","A188992-","T188993-","A188994-","G188995-","G188996-","T188997-","C188998-","A188999-","T189000-","T189001-","T189002-","T189003-","T189004-","T189005-","A189006-","A189007-","A189008-","C189009-","A189010-","T189011-","G189012-","G189013-","A189014-","T189015-","A189016-","G189017-","A189018-","A189019-","A189020-","C189021-","C189022-","A189023-","A189024-","G189025-","T190132-","A190133-","T190134-","T190135-","A190136-","A190137-","T190138-","G190139-","G190140-","A190141-","T190142-","A190143-","T190144-","A190145-","T190146-","A190147-","G190148-","A190149-","T190150-","A190151-","A190152-","C190153-","G190154-","C190155-","A190156-","A190157-","T190158-","A190159-","G190160-","G190161-","G190162-","A190163-","C190164-","T190165-","A190166-","A190167-","T190168-","A190169-","G190170-","T190171-","A190172-","T190173-","T190174-","G190175-","T190176-","A190177-","A190178-","A190179-","A190180-","G190181-","A190182-","T190183-","A190184-","T190185-","G190345A"],"OPG071":["R246Q"],"OPG192":["T46-","D47-","D48-","N49-","N50-","E51-","L52-","V53-","L54-","N55-","F56-","K57-","E58-","Y59-","T60-","I61-","S62-","I63-","I64-","T65-","E66-","S67-","C68-","D69-","V70-","G71-","F72-","D73-","S74-","I75-","D76-","I77-","D78-","V79-","I80-","N81-","D82-","Y83-","K84-","I85-","I86-","D87-","M88-","Y89-","T90-"],"OPG195":["T118N","L119-","C120-","I121-","S122-","V123-","Y124-","C125-","D126-","Q127-","E128-","A129-","G130-","D131-","I172-","L210-","K211-","S212-","K213-","A214-","L215-","H216-"]},"labels":{"aa":"OPG071: R246Q; OPG192: T46-, D47-, D48-, N49-, N50-, E51-, L52-, V53-, L54-, N55-, F56-, K57-, E58-, Y59-, T60-, I61-, S62-, I63-, I64-, T65-, E66-, S67-, C68-, D69-, V70-, G71-, F72-, D73-, S74-, I75-, D76-, I77-, D78-, V79-, I80-, N81-, D82-, Y83-, K84-, I85-, I86-, D87-, M88-, Y89-, T90-; OPG195: T118N, L119-, C120-, I121-, S122-, V123-, Y124-, C125-, D126-, Q127-, E128-, A129-, G130-, D131-, I172-, L210-, K211-, S212-, K213-, A214-, L215-, H216-"}}},{"name":"NODE_0000023","node_attrs":{"div":19,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["C23353T","C51809T","G69678A","C125492T","C128174T","-188889A"],"OPG039":["D256N"],"OPG071":["R877Q"],"OPG146":["D50N"]},"labels":{"aa":"OPG039: D256N; OPG071: R877Q; OPG146: D50N"}},"children":[{"name":"NODE_0000024","node_attrs":{"div":20,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["T27971C","A146894-","A146896-","A146901-","A146906-","A146908-","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","-173314A","-173315T","-173316A","-173317T"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}},"children":[{"name":"MK783033","node_attrs":{"div":30,"accession":"MK783033","author":{"author":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J.","value":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, NCEZID/DHCPP/PRB"},"lineage":{"value":"A.3"},"strain":{"value":"MK783033"},"date":{"value":"2017-10-09"},"strain_display":{"value":"Nigeria/MK783033/2017-10-09"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-608T","C25731T","C25768T","C26020T","A56968G","G102267T","C117099T","G129583A","C155707T","G161701A","T187428C"],"OPG042":["D360N"],"OPG074":["L53S"],"OPG121":["G160C"],"OPG136":["R830Q"],"OPG188":["V36I"]},"labels":{"aa":"OPG042: D360N; OPG074: L53S; OPG121: G160C; OPG136: R830Q; OPG188: V36I"}}},{"name":"OP535335","node_attrs":{"div":20,"accession":"OP535335","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"lineage":{"value":"A.3"},"strain":{"value":"MPXV_Nigeria_2017_2947"},"date":{"value":"2017-10-XX"},"strain_display":{"value":"Nigeria/OP535335/2017-10-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000025","node_attrs":{"div":24,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["T607-","C92053T","C123000T","C146052T","-146895T","-146897T","-146898T","-146899T","-146900T","-146902T","-146903T","-146904T","-146905T","-146907T","-146909T","-146910T","-146911T","-146912T","C150831T","C151305T"],"OPG113":["S108L"],"OPG143":["E106K"]},"labels":{"aa":"OPG113: S108L; OPG143: E106K"}},"children":[{"name":"OP612677","node_attrs":{"div":27,"accession":"OP612677","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.3"},"strain":{"value":"MPXV/015/19"},"date":{"value":"2019-03-12"},"strain_display":{"value":"Nigeria/OP612677/2019-03-12"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C56351T","G74032A","T76087-","A89106-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","G190782A"],"OPG016":["E125K"],"OPG074":["E259K"],"OPG094":["A85T"]},"labels":{"aa":"OPG016: E125K; OPG074: E259K; OPG094: A85T"}}},{"name":"NODE_0000026","node_attrs":{"div":53,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["T606-","C2930T","C18493T","C18908T","G21898A","G23626A","C25254T","C29199T","G36901A","G44085A","G63034A","G75099A","G75144A","G76509A","C87659T","G115332A","C115572T","G122627A","C128771T","C140739T","A149394-","G151519T","G151875A","C160008T","C160312T","G165130A","G168862A","-173314A","-173315T","-173316A","-173317T","G174491A","G176289A","G176366A","C177703T","G194280A","A196614-","A196615-"],"OPG003":["E560K"],"OPG003_dup":["E560K"],"OPG037":["S179L"],"OPG039":["H165Y"],"OPG045":["E22K"],"OPG064":["S605L"],"OPG082":["S140L"],"OPG097":["H123Y"],"OPG109":["E597K"],"OPG133":["R42Q","S122F"],"OPG143":["T230M"],"OPG178":["G4V","D123N"],"OPG205":["A212T","M237I","S683L"]},"labels":{"aa":"OPG003: E560K; OPG003_dup: E560K; OPG037: S179L; OPG039: H165Y; OPG045: E22K; OPG064: S605L; OPG082: S140L; OPG097: H123Y; OPG109: E597K; OPG133: R42Q, S122F; OPG143: T230M; OPG178: G4V, D123N; OPG205: A212T, M237I, S683L"}},"children":[{"name":"OP413718","node_attrs":{"div":53,"accession":"OP413718","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"A.3"},"strain":{"value":"9000360"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP413718/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133171-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"]}}},{"name":"OP536812","node_attrs":{"div":53,"accession":"OP536812","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"A.3"},"strain":{"value":"9000450"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536812/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000027","node_attrs":{"div":18,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["C23564T","C72362T","C83326T","G87230A","G87297A","G91728A","C119296T","C121320T","G125249A","-146895T","-146897T","-146898T","-146899T","-146900T","-146902T","-146903T","-146904T","-146905T","-146907T","-146909T","-146910T","-146911T","-146912T","G148412A","C164832T","C168120T"],"OPG092":["D196N"],"OPG105":["S734L"],"OPG109":["H740Y"],"OPG136":["D98N"],"OPG139":["A17T"],"OPG145":["E435K"],"OPG193":["L263F"]},"labels":{"aa":"OPG092: D196N; OPG105: S734L; OPG109: H740Y; OPG136: D98N; OPG139: A17T; OPG145: E435K; OPG193: L263F","clade":"A.1"}},"children":[{"name":"MT903343","node_attrs":{"div":21,"accession":"MT903343","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-UK_P1"},"date":{"value":"2018-09-XX"},"strain_display":{"value":"United Kingdom/MT903343/2018-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-608T","G28838A","G92349A","-173314A","-173315T","-173316A","-173317T","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","G188494A","-196616A"],"OPG045":["A142V"],"OPG113":["E207K"]},"labels":{"aa":"OPG045: A142V; OPG113: E207K"}}},{"name":"MN648051","node_attrs":{"div":22,"accession":"MN648051","author":{"author":"Cohen Gihon,I.,Israeli,O.,Shifman,O.,Erez,N.,Melamed,S.,Paran,N.,Beth-Din,A.,Zvi,A.","value":"Cohen Gihon,I.,Israeli,O.,Shifman,O.,Erez,N.,Melamed,S.,Paran,N.,Beth-Din,A.,Zvi,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Israel"},"clade_membership":{"value":"IIb"},"institution":{"value":"Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel"},"lineage":{"value":"A.1"},"strain":{"value":"MN648051"},"date":{"value":"2018-10-04"},"strain_display":{"value":"Israel/MN648051/2018-10-04"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T607-","C8772T","C91363T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A147593T","G150568A","G177273A","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A196615-"],"OPG172":["E56V"],"OPG205":["D540N"]},"labels":{"aa":"OPG172: E56V; OPG205: D540N"}}},{"name":"MT903341","node_attrs":{"div":20,"accession":"MT903341","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-M5320_M15_Bayelsa"},"date":{"value":"2018-08-14"},"strain_display":{"value":"Nigeria/MT903341/2018-08-14"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-608T","G3153-","A3154-","T3155-","T3156-","C3157-","G3158-","A3159-","A3160-","T3161-","C3162-","T3163-","C3164-","T3165-","T3166-","T3167-","G3168-","A3169-","G3170-","G3171-","A3172-","G3173-","A3174-","C3175-","T3176-","T3177-","A3178-","T3179-","G3180-","T3181-","C3182-","A3183-","C3184-","G3185-","A3186-","C3187-","T3188-","A3189-","C3190-","A3191-","T3192-","T3193-","T3194-","T3195-","T3196-","C3197-","G3198-","A3199-","T3200-","G3201-","A3202-","T3203-","G3204-","G3205-","A3206-","A3207-","T3208-","C3209-","T3210-","A3211-","T3212-","C3213-","T3214-","T3215-","A3216-","T3217-","C3218-","G3219-","A3220-","A3221-","T3222-","G3223-","A3224-","T3225-","A3226-","T3227-","A3228-","T3229-","T3230-","T3231-","T3232-","T3233-","C3234-","A3235-","T3236-","A3237-","A3238-","A3239-","T3240-","A3241-","C3242-","A3243-","C3244-","T3245-","T3246-","T3247-","T3248-","A3249-","T3250-","A3251-","G3252-","T3253-","C3254-","C3255-","T3256-","C3257-","G3258-","T3259-","T3260-","T3261-","A3262-","A3263-","A3264-","C3265-","A3266-","G3267-","A3268-","A3269-","T3270-","T3271-","T3272-","A3273-","G3274-","T3275-","A3276-","T3277-","G3278-","T3279-","A3280-","G3281-","T3282-","T3283-","C3284-","C3285-","G3286-","C3287-","A3288-","A3289-","A3290-","T3291-","G3292-","A3293-","C3294-","T3295-","C3296-","G3297-","T3298-","C3299-","C3300-","C3301-","T3302-","T3303-","A3304-","A3305-","T3306-","A3307-","G3308-","G3309-","C3310-","A3311-","G3312-","T3313-","A3314-","G3315-","G3316-","C3317-","T3318-","A3319-","T3320-","T3321-","A3322-","T3323-","C3324-","T3325-","T3326-","C3327-","T3328-","T3329-","T3330-","A3331-","C3332-","G3333-","T3334-","A3335-","G3336-","T3337-","G3338-","A3339-","T3340-","C3341-","G3342-","T3343-","C3344-","G3345-","T3346-","A3347-","G3348-","G3349-","G3350-","A3351-","G3352-","A3353-","G3354-","A3355-","A3356-","C3357-","T3358-","C3359-","C3360-","G3361-","A3362-","C3363-","A3364-","T3365-","C3366-","T3367-","T3368-","G3369-","T3370-","A3371-","G3372-","A3373-","A3374-","C3375-","A3376-","A3377-","C3378-","G3379-","A3380-","T3381-","T3382-","T3383-","A3384-","A3385-","T3386-","C3387-","A3388-","T3389-","A3390-","G3391-","G3392-","T3393-","A3394-","G3395-","A3396-","G3397-","A3398-","T3399-","A3400-","C3401-","T3402-","T3403-","T3404-","C3405-","A3406-","G3407-","T3408-","C3409-","T3410-","G3411-","T3412-","G3413-","G3414-","T3415-","G3416-","G3417-","A3418-","T3419-","A3420-","A3421-","T3422-","G3423-","T3424-","C3425-","A3426-","T3427-","T3428-","A3429-","A3430-","C3431-","G3432-","A3433-","C3434-","A3435-","T3436-","C3437-","C3438-","G3439-","C3440-","C3441-","T3442-","T3443-","G3444-","T3445-","A3446-","T3447-","A3448-","T3449-","A3450-","A3451-","T3452-","G3453-","T3454-","T3455-","T3456-","C3457-","T3458-","G3459-","T3460-","T3461-","T3462-","T3463-","C3464-","A3465-","A3466-","A3467-","C3468-","A3469-","C3470-","C3471-","A3472-","A3473-","G3474-","T3475-","C3476-","G3477-","A3478-","A3479-","T3480-","A3481-","C3482-","T3483-","G3484-","T3485-","C3486-","T3487-","T3488-","A3489-","T3490-","C3491-","G3492-","T3493-","C3494-","T3495-","T3496-","T3497-","A3498-","G3499-","T3500-","C3501-","G3502-","G3503-","A3504-","A3505-","G3506-","G3507-","T3508-","T3509-","G3510-","A3511-","T3512-","G3513-","T3514-","C3515-","G3516-","T3517-","A3518-","T3519-","C3520-","C3521-","G3522-","A3523-","T3524-","G3525-","T3526-","A3527-","T3528-","A3529-","C3530-","G3531-","A3532-","G3533-","G3534-","T3535-","A3536-","T3537-","G3538-","A3539-","G3540-","G3541-","C3542-","A3543-","A3544-","C3545-","A3546-","T3547-","T3548-","G3549-","T3550-","T3551-","A3552-","T3553-","T3554-","G3555-","C3556-","A3557-","A3558-","T3559-","T3560-","C3561-","T3562-","G3563-","G3564-","A3565-","A3566-","G3567-","G3568-","C3569-","G3570-","G3571-","T3572-","A3573-","T3574-","G3575-","A3576-","A3577-","G3578-","A3579-","G3580-","G3581-","A3582-","G3583-","T3584-","C3585-","A3586-","T3587-","T3588-","G3589-","T3590-","A3591-","T3592-","T3593-","A3594-","T3595-","A3596-","G3597-","T3598-","A3599-","T3600-","T3601-","C3602-","G3603-","T3604-","C3605-","T3606-","T3607-","T3608-","C3609-","T3610-","G3611-","A3612-","A3613-","T3614-","G3615-","T3616-","C3617-","G3618-","A3619-","A3620-","T3621-","C3622-","T3623-","A3624-","T3625-","C3626-","T3627-","A3628-","G3629-","T3630-","A3631-","G3632-","A3633-","T3634-","A3635-","C3636-","C3637-","G3638-","T3639-","A3640-","G3641-","T3642-","A3643-","T3644-","A3645-","T3646-","T3647-","G3648-","A3649-","G3650-","A3651-","G3652-","A3653-","G3654-","C3655-","G3656-","A3657-","C3658-","T3659-","T3660-","C3661-","C3662-","A3663-","T3664-","A3665-","T3666-","C3667-","C3668-","T3669-","T3670-","G3671-","A3672-","T3673-","T3674-","A3675-","T3676-","G3677-","T3678-","T3679-","T3680-","T3681-","A3682-","T3683-","G3684-","A3685-","A3686-","T3687-","A3688-","G3689-","A3690-","T3691-","A3692-","A3693-","A3694-","G3695-","T3696-","A3697-","G3698-","A3699-","T3700-","G3701-","T3702-","T3703-","G3704-","T3705-","C3706-","C3707-","T3708-","T3709-","C3710-","T3711-","T3712-","C3713-","C3714-","T3715-","T3716-","T3717-","T3718-","G3719-","T3720-","A3721-","A3722-","T3723-","T3724-","T3725-","C3726-","C3727-","C3728-","G3729-","T3730-","A3731-","T3732-","T3733-","T3734-","T3735-","T3736-","G3737-","T3738-","T3739-","C3740-","G3741-","T3742-","G3743-","C3744-","C3745-","A3746-","A3747-","T3748-","T3749-","G3750-","A3751-","G3752-","T3753-","A3754-","A3755-","C3756-","A3757-","T3758-","T3759-","A3760-","T3761-","G3762-","A3763-","G3764-","A3765-","A3766-","T3767-","A3768-","T3769-","G3770-","A3771-","C3772-","C3773-","T3774-","G3775-","T3776-","T3777-","G3778-","C3779-","A3780-","C3781-","A3782-","A3783-","T3784-","C3785-","G3786-","T3787-","T3788-","C3789-","T3790-","T3791-","T3792-","A3793-","T3794-","G3795-","T3796-","A3797-","T3798-","T3799-","C3800-","C3801-","A3802-","T3803-","G3804-","A3805-","T3806-","G3807-","G3808-","G3809-","T3810-","G3811-","T3812-","A3813-","C3814-","A3815-","A3816-","T3817-","C3818-","A3819-","A3820-","G3821-","A3822-","T3823-","T3824-","A3825-","T3826-","T3827-","A3828-","C3829-","G3830-","T3831-","A3832-","T3833-","C3834-","C3835-","T3836-","C3837-","G3838-","T3839-","A3840-","T3841-","C3842-","G3843-","G3844-","C3845-","T3846-","C3847-","C3848-","T3849-","C3850-","G3851-","A3852-","G3853-","A3854-","T3855-","A3856-","A3857-","A3858-","A3859-","G3860-","A3861-","G3862-","C3863-","A3864-","T3865-","A3866-","C3867-","A3868-","C3869-","C3870-","A3871-","C3872-","A3873-","C3874-","G3875-","A3876-","G3877-","G3878-","A3879-","C3880-","T3881-","A3882-","T3883-","G3884-","T3885-","T3886-","T3887-","G3888-","G3889-","T3890-","A3891-","T3892-","A3893-","C3894-","T3895-","G3896-","T3897-","T3898-","G3899-","A3900-","A3901-","G3902-","G3903-","T3904-","A3905-","A3906-","G3907-","T3908-","G3909-","T3910-","G3911-","T3912-","A3913-","A3914-","C3915-","G3916-","G3917-","C3918-","G3919-","T3920-","A3921-","T3922-","T3923-","T3924-","C3925-","C3926-","G3927-","A3928-","T3929-","T3930-","T3931-","T3932-","C3933-","G3934-","T3935-","A3936-","A3937-","C3938-","C3939-","G3940-","C3941-","G3942-","T3943-","T3944-","A3945-","A3946-","T3947-","G3948-","T3949-","T3950-","T3951-","G3952-","C3953-","T3954-","C3955-","C3956-","A3957-","T3958-","G3959-","A3960-","T3961-","C3962-","T3963-","A3964-","T3965-","T3966-","A3967-","T3968-","C3969-","G3970-","C3971-","G3972-","T3973-","A3974-","G3975-","A3976-","T3977-","G3978-","A3979-","A3980-","T3981-","C3982-","G3983-","C3984-","T3985-","T3986-","C3987-","T3988-","C3989-","A3990-","G3991-","C3992-","T3993-","C3994-","G3995-","C3996-","A3997-","T3998-","C3999-","T4000-","T4001-","A4002-","G4003-","T4004-","G4005-","T4006-","G4007-","A4008-","C4009-","T4010-","C4011-","T4012-","T4013-","T4014-","G4015-","A4016-","C4017-","T4018-","T4019-","G4020-","T4021-","A4022-","A4023-","T4024-","A4025-","A4026-","T4027-","T4028-","G4029-","C4030-","T4031-","T4032-","T4033-","C4034-","G4035-","T4036-","G4037-","G4038-","A4039-","A4040-","C4041-","G4042-","C4043-","G4044-","G4045-","A4046-","T4047-","A4048-","T4049-","G4050-","T4051-","G4052-","T4053-","T4054-","T4055-","A4056-","C4057-","A4058-","G4059-","T4060-","A4061-","G4062-","T4063-","A4064-","A4065-","T4066-","G4067-","A4068-","A4069-","G4070-","A4071-","G4072-","A4073-","A4074-","G4075-","T4076-","G4077-","A4078-","G4079-","T4080-","C4081-","C4082-","A4083-","T4084-","C4085-","C4086-","T4087-","C4088-","A4089-","T4090-","C4091-","G4092-","A4093-","C4094-","G4095-","C4096-","A4097-","A4098-","T4099-","T4100-","A4101-","G4102-","G4103-","G4104-","T4105-","C4106-","A4107-","G4108-","A4109-","T4110-","C4111-","C4112-","T4113-","T4114-","T4115-","A4116-","G4117-","T4118-","C4119-","A4120-","A4121-","T4122-","A4123-","A4124-","T4125-","T4126-","T4127-","G4128-","T4129-","A4130-","C4131-","A4132-","G4133-","A4134-","A4135-","C4136-","G4137-","T4138-","A4139-","A4140-","T4141-","A4142-","G4143-","T4144-","T4145-","T4146-","A4147-","A4148-","G4149-","C4150-","T4151-","C4152-","C4153-","C4154-","A4155-","T4156-","T4157-","G4158-","A4159-","A4160-","T4161-","T4162-","T4163-","A4164-","T4165-","A4166-","T4167-","C4168-","T4169-","A4170-","A4171-","G4172-","A4173-","T4174-","A4175-","A4176-","C4177-","A4178-","C4179-","A4180-","G4181-","C4182-","A4183-","A4184-","T4185-","A4186-","G4187-","A4188-","T4189-","C4190-","G4191-","G4192-","A4193-","T4194-","G4195-","A4196-","T4197-","T4198-","T4199-","A4200-","C4201-","T4202-","A4203-","A4204-","A4205-","G4206-","T4207-","C4208-","A4209-","T4210-","C4211-","A4212-","A4213-","T4214-","G4215-","G4216-","G4217-","G4218-","T4219-","C4220-","C4221-","G4222-","T4223-","T4224-","A4225-","G4226-","T4227-","A4228-","T4229-","A4230-","T4231-","C4232-","A4233-","A4234-","A4235-","G4236-","A4237-","T4238-","C4239-","T4240-","T4241-","G4242-","T4243-","T4244-","A4245-","T4246-","C4247-","G4248-","A4249-","T4250-","T4251-","G4252-","A4253-","T4254-","A4255-","G4256-","T4257-","G4258-","A4259-","A4260-","T4261-","G4262-","A4263-","A4264-","T4265-","C4266-","A4267-","G4268-","A4269-","T4270-","A4271-","G4272-","T4273-","G4274-","G4275-","T4276-","G4277-","T4278-","A4279-","G4280-","A4281-","G4282-","G4283-","A4284-","A4285-","T4286-","A4287-","T4288-","G4289-","T4290-","C4291-","C4292-","T4293-","T4294-","T4295-","T4296-","T4297-","T4298-","A4299-","T4300-","C4301-","C4302-","T4303-","T4304-","G4305-","C4306-","T4307-","A4308-","T4309-","C4310-","A4311-","A4312-","A4313-","G4314-","T4315-","T4316-","A4317-","C4318-","G4319-","C4320-","A4321-","T4322-","G4323-","C4324-","C4325-","G4326-","T4327-","G4328-","G4329-","C4330-","G4331-","T4332-","A4333-","A4334-","C4335-","A4336-","A4337-","T4338-","A4339-","T4340-","C4341-","T4342-","T4343-","T4344-","A4345-","A4346-","T4347-","A4348-","C4349-","A4350-","G4351-","A4352-","T4353-","G4354-","G4355-","A4356-","T4357-","T4358-","A4359-","A4360-","A4361-","T4362-","C4363-","G4364-","T4365-","G4366-","T4367-","A4368-","T4369-","T4370-","C4371-","A4372-","T4373-","C4374-","G4375-","T4376-","A4377-","T4378-","A4379-","G4380-","C4381-","A4382-","A4383-","T4384-","G4385-","T4386-","A4387-","A4388-","T4389-","G4390-","G4391-","A4392-","G4393-","A4394-","G4395-","T4396-","T4397-","A4398-","C4399-","C4400-","A4401-","C4402-","A4403-","T4404-","T4405-","T4406-","T4407-","A4408-","G4409-","T4410-","C4411-","G4412-","T4413-","T4414-","T4415-","A4416-","T4417-","T4418-","C4419-","A4420-","G4421-","A4422-","T4423-","C4424-","G4425-","C4426-","A4427-","G4428-","T4429-","G4430-","T4431-","T4432-","T4433-","A4434-","A4435-","T4436-","A4437-","A4438-","C4439-","T4440-","A4441-","A4442-","T4443-","T4444-","T4445-","A4446-","A4447-","A4448-","C4449-","A4450-","G4451-","A4452-","T4453-","G4454-","A4455-","G4456-","A4457-","T4458-","G4459-","A4460-","T4461-","A4462-","T4463-","A4464-","T4465-","C4466-","C4467-","A4468-","C4469-","A4470-","T4471-","C4472-","A4473-","A4474-","A4475-","G4476-","A4477-","A4478-","T4479-","G4480-","C4481-","G4482-","A4483-","G4484-","A4485-","T4486-","A4487-","C4488-","A4489-","T4490-","A4491-","T4492-","G4493-","A4494-","C4495-","A4496-","G4497-","A4498-","C4499-","A4500-","T4501-","T4502-","A4503-","T4504-","T4505-","G4506-","A4507-","C4508-","A4509-","G4510-","A4511-","A4512-","A4513-","T4514-","G4515-","T4516-","G4517-","A4518-","C4519-","C4520-","T4521-","T4522-","C4523-","A4524-","T4525-","T4526-","A4527-","T4528-","C4529-","A4530-","C4531-","C4532-","G4533-","T4534-","C4535-","G4536-","T4537-","C4538-","C4539-","A4540-","T4541-","A4542-","A4543-","A4544-","T4545-","G4546-","C4547-","G4548-","T4549-","T4550-","A4551-","G4552-","G4553-","T4554-","A4555-","C4556-","G4557-","T4558-","A4559-","C4560-","C4561-","A4562-","C4563-","A4564-","T4565-","A4566-","C4567-","T4568-","A4569-","T4570-","C4571-","G4572-","T4573-","T4574-","A4575-","A4576-","C4577-","G4578-","A4579-","T4580-","G4581-","C4582-","G4583-","C4584-","A4585-","C4586-","A4587-","A4588-","T4589-","C4590-","T4591-","C4592-","G4593-","T4594-","C4595-","C4596-","A4597-","T4598-","T4599-","T4600-","C4601-","A4602-","T4603-","C4604-","C4605-","A4606-","T4607-","C4608-","T4609-","T4610-","C4611-","A4612-","T4613-","A4614-","A4615-","T4616-","G4617-","A4618-","T4619-","T4620-","T4621-","A4622-","C4623-","T4624-","T4625-","T4626-","T4627-","T4628-","C4629-","A4630-","T4631-","A4632-","A4633-","T4634-","T4635-","A4636-","G4637-","A4638-","G4639-","A4640-","A4641-","A4642-","A4643-","A4644-","G4645-","A4646-","T4647-","C4648-","A4649-","A4650-","G4651-","G4652-","T4653-","A4654-","T4655-","A4656-","A4657-","A4658-","A4659-","A4660-","T4661-","T4662-","A4663-","G4664-","A4665-","A4666-","G4667-","T4668-","G4669-","T4670-","T4671-","A4672-","G4673-","A4674-","C4675-","T4676-","A4677-","T4678-","A4679-","A4680-","A4681-","C4682-","T4683-","A4684-","A4685-","C4686-","T4687-","T4688-","A4689-","T4690-","G4691-","A4692-","C4693-","T4694-","T4695-","A4696-","A4697-","C4698-","T4699-","A4700-","A4701-","C4702-","T4703-","T4704-","A4705-","T4706-","G4707-","A4708-","C4709-","T4710-","T4711-","A4712-","A4713-","C4714-","T4715-","A4716-","A4717-","C4718-","T4719-","T4720-","A4721-","T4722-","G4723-","A4724-","C4725-","T4726-","T4727-","A4728-","A4729-","C4730-","T4731-","A4732-","A4733-","C4734-","T4735-","T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","A4748-","A4749-","C4750-","T4751-","T4752-","A4753-","T4754-","G4755-","A4756-","C4757-","T4758-","T4759-","A4760-","A4761-","C4762-","T4763-","A4764-","A4765-","C4766-","T4767-","T4768-","A4769-","T4770-","G4771-","A4772-","C4773-","T4774-","T4775-","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","A4807-","T4808-","T4809-","A4810-","A4811-","C4812-","T4813-","C4814-","A4815-","T4816-","T4817-","T4818-","C4819-","A4820-","A4821-","G4822-","A4823-","A4824-","A4825-","G4826-","G4827-","T4828-","G4829-","G4830-","G4831-","T4832-","G4833-","G4834-","A4835-","T4836-","A4837-","G4838-","A4839-","A4840-","C4841-","T4842-","C4843-","T4844-","A4845-","T4846-","A4847-","T4848-","G4849-","A4850-","C4851-","A4852-","G4853-","C4854-","T4855-","T4856-","G4857-","T4858-","G4859-","A4860-","A4861-","A4862-","C4863-","A4864-","A4865-","T4866-","T4867-","A4868-","G4869-","A4870-","T4871-","C4872-","C4873-","C4874-","T4875-","A4876-","A4877-","T4878-","T4879-","T4880-","C4881-","T4882-","A4883-","A4884-","T4885-","G4886-","G4887-","A4888-","A4889-","G4890-","T4891-","T4892-","T4893-","T4894-","G4895-","A4896-","T4897-","A4898-","G4899-","G4900-","A4901-","G4902-","A4903-","T4904-","T4905-","G4906-","T4907-","C4908-","A4909-","T4910-","C4911-","A4912-","G4913-","T4914-","T4915-","G4916-","A4917-","T4918-","A4919-","C4920-","A4921-","T4922-","T4923-","G4924-","T4925-","T4926-","T4927-","A4928-","T4929-","T4930-","A4931-","T4932-","C4933-","T4934-","C4935-","A4936-","T4937-","C4938-","T4939-","A4940-","T4941-","T4942-","A4943-","G4944-","A4945-","G4946-","C4947-","A4948-","C4949-","G4950-","T4951-","C4952-","T4953-","G4954-","T4955-","T4956-","T4957-","A4958-","G4959-","A4960-","G4961-","C4962-","T4963-","T4964-","T4965-","A4966-","G4967-","T4968-","G4969-","A4970-","C4971-","C4972-","T4973-","G4974-","C4975-","T4976-","C4977-","G4978-","G4979-","T4980-","T4981-","A4982-","C4983-","T4984-","T4985-","C4986-","T4987-","G4988-","T4989-","G4990-","T4991-","A4992-","A4993-","A4994-","T4995-","C4996-","T4997-","T4998-","G4999-","A5000-","A5001-","T5002-","C5003-","C5004-","T5005-","T5006-","T5007-","A5008-","G5009-","T5010-","G5011-","A5012-","T5013-","A5014-","C5015-","A5016-","C5017-","T5018-","G5019-","T5020-","G5021-","T5022-","C5023-","A5024-","A5025-","A5026-","A5027-","C5028-","T5029-","G5030-","G5031-","A5032-","T5033-","G5034-","T5035-","T5036-","T5037-","A5038-","G5039-","A5040-","A5041-","T5042-","A5043-","C5044-","C5045-","T5046-","A5047-","T5048-","G5049-","T5050-","A5051-","G5052-","A5053-","A5054-","T5055-","A5056-","T5057-","G5058-","G5059-","G5060-","A5061-","A5062-","G5063-","C5064-","A5065-","T5066-","G5067-","C5068-","T5069-","T5070-","G5071-","T5072-","T5073-","T5074-","T5075-","T5076-","G5077-","T5078-","C5079-","T5080-","C5081-","T5082-","A5083-","T5084-","T5085-","A5086-","T5087-","A5088-","G5089-","A5090-","T5091-","T5092-","A5093-","A5094-","C5095-","T5096-","C5097-","A5098-","T5099-","A5100-","C5101-","A5102-","T5103-","G5104-","G5105-","T5106-","T5107-","G5108-","T5109-","A5110-","T5111-","T5112-","A5113-","T5114-","G5115-","A5116-","A5117-","T5118-","T5119-","T5120-","T5121-","C5122-","A5123-","T5124-","C5125-","T5126-","G5127-","C5128-","C5129-","T5130-","A5131-","A5132-","T5133-","G5134-","T5135-","A5136-","C5137-","T5138-","C5139-","C5140-","A5141-","A5142-","T5143-","T5144-","C5145-","T5146-","T5147-","G5148-","T5149-","T5150-","T5151-","A5152-","C5153-","A5154-","A5155-","T5156-","C5157-","A5158-","A5159-","T5160-","T5161-","A5162-","T5163-","A5164-","T5165-","A5166-","A5167-","T5168-","C5169-","A5170-","A5171-","A5172-","G5173-","A5174-","G5175-","T5176-","G5177-","A5178-","T5179-","G5180-","A5181-","T5182-","G5183-","C5184-","A5185-","T5186-","A5187-","C5188-","A5189-","C5190-","A5191-","T5192-","T5193-","A5194-","C5195-","A5196-","A5197-","A5198-","G5199-","T5200-","G5201-","A5202-","A5203-","T5204-","A5205-","A5206-","T5207-","C5208-","T5209-","A5210-","C5211-","C5212-","A5213-","T5214-","C5215-","A5216-","T5217-","A5218-","A5219-","A5220-","A5221-","T5222-","A5223-","C5224-","T5225-","T5226-","G5227-","A5228-","T5229-","A5230-","C5231-","A5232-","G5233-","A5234-","G5235-","C5236-","T5237-","T5238-","T5239-","A5240-","T5241-","C5242-","A5243-","C5244-","A5245-","T5246-","C5247-","A5248-","T5249-","G5250-","G5251-","T5252-","T5253-","T5254-","T5255-","C5256-","A5257-","A5258-","T5259-","T5260-","G5261-","T5262-","A5263-","T5264-","T5265-","A5266-","T5267-","T5268-","A5269-","A5270-","G5271-","T5272-","A5273-","T5274-","A5275-","G5276-","C5277-","T5278-","A5279-","A5280-","T5281-","T5282-","T5283-","T5284-","A5285-","T5286-","A5287-","C5288-","A5289-","G5290-","T5291-","C5292-","A5293-","A5294-","T5295-","A5296-","G5297-","A5298-","C5299-","A5300-","A5301-","T5302-","G5303-","G5304-","T5305-","T5306-","C5307-","T5308-","C5309-","T5310-","A5311-","A5312-","G5313-","C5314-","A5315-","A5316-","T5317-","A5318-","T5319-","T5320-","T5321-","C5322-","T5323-","A5324-","A5325-","T5326-","A5327-","T5328-","T5329-","T5330-","T5331-","A5332-","A5333-","G5334-","A5335-","T5336-","G5337-","T5338-","G5339-","C5340-","T5341-","T5342-","C5343-","C5344-","C5345-","T5346-","A5347-","C5348-","G5349-","G5350-","G5351-","C5352-","G5353-","A5354-","T5355-","G5356-","A5357-","C5358-","A5359-","G5360-","A5361-","T5362-","C5363-","C5364-","C5365-","C5366-","T5367-","A5368-","T5369-","C5370-","C5371-","A5372-","C5373-","G5374-","G5375-","C5376-","C5377-","A5378-","C5379-","G5380-","T5381-","C5382-","A5383-","A5384-","G5385-","A5386-","C5387-","A5388-","T5389-","G5390-","T5391-","A5392-","T5393-","A5394-","T5395-","C5396-","C5397-","A5398-","T5399-","T5400-","A5401-","C5402-","T5403-","C5404-","A5405-","T5406-","T5407-","A5408-","C5409-","T5410-","G5411-","C5412-","G5413-","T5414-","T5415-","G5416-","A5417-","C5418-","A5419-","T5420-","T5421-","T5422-","G5423-","C5424-","T5425-","C5426-","C5427-","A5428-","T5429-","T5430-","T5431-","T5432-","C5433-","T5434-","A5435-","A5436-","T5437-","A5438-","G5439-","C5440-","C5441-","A5442-","T5443-","G5444-","A5445-","T5446-","A5447-","C5448-","T5449-","A5450-","A5451-","A5452-","T5453-","C5454-","T5455-","A5456-","T5457-","A5458-","T5459-","A5460-","A5461-","C5462-","C5463-","T5464-","G5465-","C5466-","A5467-","T5468-","A5469-","G5470-","A5471-","T5472-","A5473-","G5474-","C5475-","G5476-","C5477-","G5478-","A5479-","T5480-","A5481-","A5482-","A5483-","G5484-","C5485-","A5486-","A5487-","G5488-","G5489-","T5490-","C5491-","C5492-","T5493-","T5494-","C5495-","C5496-","A5497-","C5498-","C5499-","A5500-","G5501-","C5502-","A5503-","T5504-","C5505-","T5506-","A5507-","G5508-","T5509-","T5510-","G5511-","A5512-","T5513-","T5514-","G5515-","A5516-","T5517-","A5518-","T5519-","C5520-","T5521-","T5522-","C5523-","A5524-","A5525-","T5526-","A5527-","T5528-","A5529-","T5530-","G5531-","G5532-","G5533-","A5534-","T5535-","A5536-","C5537-","A5538-","A5539-","A5540-","G5541-","C5542-","T5543-","T5544-","A5545-","T5546-","A5547-","A5548-","A5549-","T5550-","T5551-","T5552-","C5553-","T5554-","A5555-","A5556-","T5557-","A5558-","C5559-","T5560-","G5561-","T5562-","G5563-","G5564-","G5565-","T5566-","T5567-","C5568-","A5569-","T5570-","C5571-","T5572-","A5573-","C5574-","A5575-","A5576-","G5577-","G5578-","A5579-","A5580-","T5581-","C5582-","C5583-","C5584-","C5585-","T5586-","A5587-","G5588-","T5589-","A5590-","T5591-","A5592-","C5593-","T5594-","G5595-","A5596-","A5597-","T5598-","T5599-","A5600-","T5601-","T5602-","T5603-","T5604-","A5605-","T5606-","A5607-","T5608-","A5609-","G5610-","A5611-","T5612-","C5613-","T5614-","A5615-","A5616-","T5617-","T5618-","T5619-","A5620-","A5621-","C5622-","A5623-","T5624-","C5625-","A5626-","T5627-","T5628-","T5629-","T5630-","C5631-","A5632-","T5633-","C5634-","T5635-","G5636-","G5637-","G5638-","A5639-","T5640-","A5641-","C5642-","C5643-","A5644-","C5645-","A5646-","A5647-","T5648-","T5649-","C5650-","A5651-","A5652-","A5653-","A5654-","T5655-","A5656-","A5657-","A5658-","C5659-","T5660-","C5661-","A5662-","A5663-","C5664-","A5665-","A5666-","C5667-","A5668-","C5669-","T5670-","A5671-","C5672-","T5673-","T5674-","T5675-","C5676-","C5677-","T5678-","T5679-","T5680-","T5681-","T5682-","A5683-","C5684-","A5685-","T5686-","A5687-","T5688-","T5689-","C5690-","C5691-","C5692-","C5693-","T5694-","A5695-","A5696-","A5697-","A5698-","T5699-","A5700-","G5701-","G5702-","C5703-","A5704-","T5705-","T5706-","C5707-","A5708-","A5709-","G5710-","C5711-","A5712-","T5713-","T5714-","C5715-","T5716-","A5717-","T5718-","T5719-","T5720-","T5721-","A5722-","T5723-","A5724-","T5725-","A5726-","T5727-","T5728-","A5729-","C5730-","A5731-","G5732-","C5733-","C5734-","C5735-","C5736-","A5737-","T5738-","G5739-","A5740-","T5741-","C5742-","T5743-","A5744-","C5745-","C5746-","A5747-","T5748-","A5749-","A5750-","G5751-","A5752-","T5753-","C5754-","A5755-","A5756-","C5757-","A5758-","A5759-","T5760-","G5761-","T5762-","C5763-","T5764-","A5765-","T5766-","T5767-","T5768-","C5769-","T5770-","A5771-","C5772-","A5773-","T5774-","A5775-","T5776-","G5777-","C5778-","A5779-","T5780-","T5781-","A5782-","G5783-","A5784-","T5785-","A5786-","G5787-","A5788-","T5789-","A5790-","G5791-","T5792-","A5793-","A5794-","A5795-","G5796-","T5797-","A5798-","A5799-","G5800-","A5801-","G5802-","A5803-","T5804-","C5805-","T5806-","T5807-","G5808-","C5809-","A5810-","C5811-","A5812-","G5813-","A5814-","A5815-","T5816-","T5817-","A5818-","C5819-","A5820-","A5821-","T5822-","T5823-","C5824-","T5825-","T5826-","A5827-","A5828-","T5829-","A5830-","A5831-","T5832-","T5833-","A5834-","T5835-","A5836-","G5837-","A5838-","G5839-","A5840-","A5841-","A5842-","A5843-","T5844-","A5845-","T5846-","C5847-","T5848-","T5849-","C5850-","C5851-","A5852-","T5853-","A5854-","T5855-","A5856-","A5857-","T5858-","T5859-","C5860-","T5861-","T5862-","T5863-","G5864-","A5865-","C5866-","A5867-","C5868-","T5869-","A5870-","A5871-","T5872-","G5873-","C5874-","A5875-","G5876-","A5877-","T5878-","A5879-","T5880-","A5881-","A5882-","T5883-","A5884-","T5885-","C5886-","T5887-","T5888-","T5889-","A5890-","T5891-","A5892-","T5893-","G5894-","T5895-","A5896-","A5897-","T5898-","A5899-","T5900-","A5901-","T5902-","G5903-","C5904-","A5905-","A5906-","A5907-","C5908-","A5909-","G5910-","T5911-","C5912-","T5913-","A5914-","T5915-","C5916-","T5917-","A5918-","C5919-","T5920-","A5921-","T5922-","A5923-","T5924-","A5925-","C5926-","T5927-","G5928-","A5929-","T5930-","C5931-","A5932-","A5933-","T5934-","A5935-","T5936-","T5937-","A5938-","T5939-","C5940-","T5941-","C5942-","T5943-","A5944-","T5945-","G5946-","A5947-","A5948-","T5949-","C5950-","C5951-","T5952-","A5953-","A5954-","A5955-","A5956-","T5957-","A5958-","A5959-","T5960-","C5961-","A5962-","T5963-","A5964-","C5965-","A5966-","G5967-","A5968-","A5969-","C5970-","A5971-","T5972-","C5973-","T5974-","A5975-","C5976-","A5977-","G5978-","G5979-","A5980-","T5981-","C5982-","A5983-","C5984-","A5985-","A5986-","A5987-","T5988-","T5989-","G5990-","G5991-","T5992-","T5993-","C5994-","A5995-","A5996-","G5997-","G5998-","A5999-","G6000-","A6001-","A6002-","A6003-","T6004-","C6005-","T6006-","A6007-","T6008-","C6009-","A6010-","A6011-","A6012-","T6013-","A6014-","T6015-","T6016-","T6017-","T6018-","C6019-","C6020-","T6021-","G6022-","T6023-","C6024-","A6025-","A6026-","C6027-","A6028-","A6029-","C6030-","T6031-","G6032-","G6033-","T6034-","T6035-","C6036-","T6037-","A6038-","G6039-","A6040-","A6041-","C6042-","A6043-","T6044-","A6045-","A6046-","C6047-","A6048-","G6049-","T6050-","C6051-","A6052-","A6053-","C6054-","A6055-","C6056-","C6057-","T6058-","A6059-","A6060-","T6061-","C6062-","C6063-","A6064-","T6065-","G6066-","T6067-","T6068-","T6069-","T6070-","T6071-","T6072-","A6073-","T6074-","A6075-","A6076-","T6077-","C6078-","A6079-","T6080-","C6081-","T6082-","A6083-","C6084-","C6085-","A6086-","A6087-","A6088-","G6089-","A6090-","T6091-","A6092-","A6093-","T6094-","G6095-","A6096-","C6097-","C6098-","A6099-","A6100-","A6101-","G6102-","A6103-","T6104-","C6105-","G6106-","A6107-","G6108-","G6109-","T6110-","C6111-","G6112-","T6113-","C6114-","G6115-","T6116-","G6117-","A6118-","A6119-","A6120-","C6121-","T6122-","G6123-","C6124-","T6125-","C6126-","A6127-","T6128-","C6129-","G6130-","A6131-","C6132-","A6133-","G6134-","C6135-","C6136-","A6137-","T6138-","G6139-","A6140-","A6141-","A6142-","T6143-","C6144-","T6145-","A6146-","C6147-","C6148-","G6149-","A6150-","C6151-","T6152-","C6153-","C6154-","A6155-","T6156-","G6157-","G6158-","T6159-","G6160-","C6161-","G6162-","A6163-","A6164-","T6165-","C6166-","G6167-","C6168-","A6169-","C6170-","T6171-","G6172-","T6173-","C6174-","T6175-","T6176-","A6177-","T6178-","T6179-","C6180-","G6181-","C6182-","C6183-","A6184-","T6185-","T6186-","G6187-","A6188-","T6189-","T6190-","T6191-","T6192-","C6193-","A6194-","T6195-","T6196-","T6197-","T6198-","T6199-","T6200-","A6201-","T6202-","A6203-","A6204-","T6205-","T6206-","A6207-","T6208-","G6209-","T6210-","A6211-","C6212-","A6213-","T6214-","G6215-","T6216-","T6217-","T6218-","T6219-","C6220-","C6221-","T6222-","T6223-","C6224-","T6225-","A6226-","T6227-","T6228-","C6229-","T6230-","C6231-","A6232-","A6233-","G6234-","A6235-","G6236-","T6237-","C6238-","T6239-","A6240-","C6241-","A6242-","A6243-","A6244-","A6245-","A6246-","T6247-","A6248-","T6249-","A6250-","T6251-","T6252-","T6253-","T6254-","T6255-","T6256-","C6257-","G6258-","A6259-","T6260-","A6261-","T6262-","C6263-","T6264-","A6265-","A6266-","G6267-","T6268-","A6269-","C6270-","T6271-","A6272-","A6273-","G6274-","T6275-","T6276-","T6277-","T6278-","T6279-","T6280-","T6281-","A6282-","C6283-","T6284-","G6285-","T6286-","T6287-","T6288-","T6289-","T6290-","G6291-","T6292-","T6293-","A6294-","C6295-","T6296-","G6297-","T6298-","C6299-","T6300-","T6301-","C6302-","C6303-","A6304-","T6305-","T6306-","C6307-","T6308-","T6309-","C6310-","T6311-","A6312-","A6313-","C6314-","T6315-","A6316-","A6317-","A6318-","G6319-","A6320-","T6321-","C6322-","T6323-","G6324-","A6325-","G6326-","A6327-","T6328-","A6329-","A6330-","A6331-","T6332-","T6333-","A6334-","T6335-","A6336-","C6337-","A6338-","A6339-","T6340-","C6341-","T6342-","T6343-","C6344-","G6345-","C6346-","T6347-","A6348-","T6349-","C6350-","G6351-","A6352-","A6353-","C6354-","C6355-","A6356-","T6357-","T6358-","T6359-","T6360-","T6361-","G6362-","T6363-","A6364-","G6365-","T6366-","C6367-","T6368-","A6369-","A6370-","A6371-","G6372-","C6373-","C6374-","T6375-","G6376-","A6377-","A6378-","G6379-","T6380-","A6381-","A6382-","T6383-","T6384-","A6385-","A6386-","C6387-","C6388-","A6389-","A6390-","C6391-","T6392-","G6393-","T6394-","T6395-","T6396-","T6397-","T6398-","A6399-","T6400-","T6401-","A6402-","G6403-","T6404-","G6405-","G6406-","C6407-","T6408-","T6409-","T6410-","T6411-","T6412-","T6413-","C6414-","G6415-","A6416-","T6417-","C6418-","T6419-","A6420-","T6421-","C6422-","C6423-","T6424-","C6425-","G6426-","T6427-","C6428-","C6429-","T6430-","C6431-","T6432-","C6433-","A6434-","T6435-","C6436-","A6437-","T6438-","C6439-","C6440-","T6441-","T6442-","A6443-","T6444-","A6445-","T6446-","T6447-","A6448-","T6449-","T6450-","A6451-","T6452-","C6453-","A6454-","T6455-","T6456-","A6457-","T6458-","T6459-","A6460-","T6461-","C6462-","A6463-","T6464-","A6465-","G6466-","T6467-","C6468-","T6469-","A6470-","T6471-","T6472-","A6473-","A6474-","A6475-","C6476-","A6477-","C6478-","A6479-","A6480-","A6481-","T6482-","C6483-","A6484-","T6485-","C6486-","T6487-","A6488-","C6489-","G6490-","T6491-","T6492-","T6493-","A6494-","T6495-","A6496-","A6497-","C6498-","A6499-","A6500-","C6501-","A6502-","T6503-","T6504-","C6505-","T6506-","C6507-","A6508-","T6509-","T6510-","A6511-","T6512-","T6513-","A6514-","A6515-","T6516-","T6517-","A6518-","G6519-","T6520-","T6521-","C6522-","T6523-","G6524-","T6525-","A6526-","G6527-","A6528-","A6529-","T6530-","A6531-","T6532-","C6533-","T6534-","T6535-","T6536-","A6537-","A6538-","T6539-","A6540-","A6541-","T6542-","T6543-","T6544-","G6545-","G6546-","C6547-","T6548-","A6549-","T6550-","A6551-","C6552-","A6553-","T6554-","C6555-","T6556-","G6557-","T6558-","T6559-","C6560-","A6561-","A6562-","T6563-","A6564-","C6565-","T6566-","A6567-","T6568-","C6569-","T6570-","A6571-","T6572-","T6573-","G6574-","A6575-","T6576-","G6577-","A6578-","T6579-","T6580-","T6581-","C6582-","T6583-","T6584-","T6585-","T6586-","T6587-","T6588-","A6589-","A6590-","G6591-","A6592-","C6593-","T6594-","T6595-","A6596-","A6597-","A6598-","C6599-","T6600-","A6601-","G6602-","T6603-","T6604-","A6605-","T6606-","G6607-","G6608-","T6609-","A6610-","A6611-","T6612-","G6613-","A6614-","C6615-","G6616-","A6617-","T6618-","G6619-","A6620-","A6621-","A6622-","T6623-","C6624-","G6625-","A6626-","G6627-","T6628-","A6629-","G6630-","T6631-","A6632-","A6633-","C6634-","T6635-","T6636-","C6637-","T6638-","A6639-","A6640-","T6641-","A6642-","A6643-","A6644-","G6645-","A6646-","C6647-","T6648-","T6649-","G6650-","A6651-","T6652-","A6653-","T6654-","C6655-","A6656-","T6657-","T6658-","A6659-","T6660-","C6661-","A6662-","T6663-","A6664-","T6665-","G6666-","T6667-","T6668-","T6669-","G6670-","A6671-","T6672-","C6673-","G6674-","T6675-","C6676-","A6677-","T6678-","A6679-","G6680-","T6681-","T6682-","A6683-","A6684-","T6685-","A6686-","G6687-","T6688-","G6689-","T6690-","G6691-","G6692-","C6693-","T6694-","A6695-","A6696-","A6697-","T6698-","G6699-","G6700-","T6701-","A6702-","C6703-","T6704-","G6705-","T6706-","T6707-","A6708-","A6709-","T6710-","A6711-","A6712-","G6713-","T6714-","T6715-","T6716-","A6717-","T6718-","A6719-","G6720-","A6721-","C6722-","A6723-","A6724-","T6725-","A6726-","T6727-","C6728-","A6729-","T6730-","A6731-","G6732-","T6733-","A6734-","T6735-","T6736-","T6737-","T6738-","C6739-","T6740-","T6741-","T6742-","C6743-","C6744-","A6745-","G6746-","A6747-","A6748-","T6749-","T6750-","A6751-","G6752-","A6753-","T6754-","T6755-","A6756-","T6757-","T6758-","T6759-","T6760-","T6761-","T6762-","T6763-","A6764-","A6765-","A6766-","T6767-","A6768-","C6769-","T6770-","G6771-","A6772-","T6773-","C6774-","C6775-","T6776-","C6777-","A6778-","C6779-","A6780-","A6781-","T6782-","T6783-","C6784-","C6785-","G6786-","T6787-","G6788-","A6789-","T6790-","G6791-","T6792-","A6793-","G6794-","C6795-","A6796-","G6797-","T6798-","A6799-","G6800-","T6801-","T6802-","G6803-","G6804-","T6805-","G6806-","C6807-","A6808-","T6809-","G6810-","G6811-","T6812-","C6813-","T6814-","A6815-","T6816-","A6817-","T6818-","C6819-","G6820-","T6821-","T6822-","A6823-","A6824-","A6825-","A6826-","T6827-","G6828-","T6829-","A6830-","T6831-","C6832-","A6833-","T6834-","A6835-","T6836-","A6837-","T6838-","A6839-","A6840-","T6841-","A6842-","G6843-","T6844-","T6845-","T6846-","T6847-","C6848-","T6849-","G6850-","A6851-","C6852-","G6853-","T6854-","G6855-","G6856-","A6857-","G6858-","T6859-","A6860-","C6861-","A6862-","G6863-","A6864-","A6865-","T6866-","T6867-","T6868-","T6869-","C6870-","G6871-","A6872-","T6873-","T6874-","A6875-","A6876-","T6877-","G6878-","A6879-","G6880-","T6881-","T6882-","C6883-","A6884-","T6885-","G6886-","G6887-","T6888-","A6889-","A6890-","G6891-","G6892-","A6893-","A6894-","G6895-","G6896-","G6897-","C6898-","A6899-","A6900-","A6901-","T6902-","G6903-","C6904-","C6905-","T6906-","G6907-","T6908-","A6909-","T6910-","A6911-","T6912-","A6913-","A6914-","T6915-","A6916-","T6917-","A6918-","C6919-","A6920-","T6921-","A6922-","A6923-","G6924-","T6925-","T6926-","A6927-","A6928-","T6929-","A6930-","G6931-","T6932-","T6933-","T6934-","T6935-","T6936-","T6937-","A6938-","T6939-","C6940-","A6941-","T6942-","A6943-","T6944-","T6945-","T6946-","T6947-","C6948-","T6949-","A6950-","A6951-","T6952-","A6953-","C6954-","C6955-","A6956-","T6957-","A6958-","A6959-","T6960-","A6961-","A6962-","A6963-","A6964-","A6965-","T6966-","T6967-","A6968-","T6969-","C6970-","A6971-","T6972-","T6973-","A6974-","T6975-","T6976-","G6977-","C6978-","G6979-","T6980-","T6981-","T6982-","G6983-","G6984-","T6985-","A6986-","G6987-","T6988-","T6989-","C6990-","T6991-","G6992-","C6993-","C6994-","C6995-","T6996-","A6997-","T6998-","C6999-","A7000-","T7001-","C7002-","T7003-","A7004-","T7005-","A7006-","T7007-","C7008-","A7009-","C7010-","T7011-","G7012-","T7013-","C7014-","A7015-","C7016-","T7017-","C7018-","T7019-","C7020-","G7021-","C7022-","T7023-","C7024-","T7025-","C7026-","A7027-","C7028-","T7029-","A7030-","T7031-","A7032-","T7033-","C7034-","T7035-","T7036-","C7037-","T7038-","A7039-","A7040-","A7041-","A7042-","T7043-","T7044-","A7045-","C7046-","A7047-","A7048-","A7049-","C7050-","A7051-","A7052-","C7053-","T7054-","G7055-","G7056-","A7057-","T7058-","A7059-","T7060-","T7061-","C7062-","G7063-","A7064-","T7065-","A7066-","A7067-","C7068-","A7069-","G7070-","C7071-","A7072-","T7073-","T7074-","T7075-","G7076-","T7077-","G7078-","T7079-","A7080-","G7081-","T7082-","T7083-","T7084-","T7085-","T7086-","G7087-","T7088-","C7089-","T7090-","T7091-","T7092-","T7093-","A7094-","C7095-","A7096-","G7097-","T7098-","A7099-","T7100-","A7101-","T7102-","A7103-","C7104-","G7105-","T7106-","T7107-","A7108-","T7109-","T7110-","G7111-","T7112-","C7113-","A7114-","A7115-","A7116-","A7117-","T7118-","C7119-","T7120-","A7121-","A7122-","A7123-","C7124-","A7125-","A7126-","A7127-","T7128-","A7129-","T7130-","T7131-","A7132-","G7133-","C7134-","A7135-","T7136-","A7137-","A7138-","T7139-","A7140-","C7141-","A7142-","T7143-","C7144-","T7145-","A7146-","T7147-","C7148-","T7149-","A7150-","T7151-","A7152-","A7153-","G7154-","A7155-","T7156-","C7157-","A7158-","G7159-","G7160-","A7161-","T7162-","C7163-","C7164-","A7165-","T7166-","G7167-","T7168-","T7169-","C7170-","G7171-","A7172-","G7173-","C7174-","A7175-","T7176-","A7177-","C7178-","T7179-","A7180-","G7181-","C7182-","C7183-","A7184-","T7185-","G7186-","T7187-","A7188-","T7189-","A7190-","T7191-","T7192-","T7193-","G7194-","T7195-","A7196-","A7197-","C7198-","T7199-","T7200-","C7201-","G7202-","T7203-","C7204-","G7205-","T7206-","A7207-","C7208-","A7209-","G7210-","C7211-","G7212-","T7213-","T7214-","A7215-","G7216-","A7217-","T7218-","C7219-","A7220-","A7221-","T7222-","A7223-","G7224-","A7225-","A7226-","T7227-","A7228-","A7229-","A7230-","C7231-","A7232-","A7233-","T7234-","C7235-","G7236-","T7237-","G7238-","T7239-","G7240-","A7241-","C7242-","G7243-","C7244-","A7245-","A7246-","C7247-","T7248-","T7249-","T7250-","T7251-","T7252-","T7253-","A7254-","C7255-","G7256-","A7257-","T7258-","C7259-","T7260-","A7261-","G7262-","T7263-","T7264-","G7265-","T7266-","A7267-","T7268-","G7269-","A7270-","G7271-","T7272-","T7273-","T7274-","A7275-","T7276-","C7277-","G7278-","T7279-","T7280-","T7281-","A7282-","C7283-","A7284-","T7285-","A7286-","A7287-","G7288-","C7289-","A7290-","A7291-","T7292-","T7293-","A7294-","A7295-","C7296-","G7297-","G7298-","C7299-","T7300-","T7301-","T7302-","A7303-","A7304-","C7305-","A7306-","G7307-","A7308-","T7309-","G7310-","A7311-","T7312-","C7313-","T7314-","G7315-","A7316-","G7317-","T7318-","A7319-","A7320-","T7321-","A7322-","A7323-","T7324-","A7325-","T7326-","A7327-","C7328-","C7329-","T7330-","C7331-","T7332-","G7333-","T7334-","T7335-","A7336-","T7337-","A7338-","C7339-","G7340-","T7341-","T7342-","T7343-","A7344-","A7345-","T7346-","G7347-","T7348-","T7349-","C7350-","A7351-","C7352-","G7353-","G7354-","T7355-","C7356-","T7357-","T7358-","A7359-","G7360-","T7361-","A7362-","T7363-","T7364-","T7365-","T7366-","T7367-","A7368-","G7369-","A7370-","T7371-","A7372-","T7373-","C7374-","A7375-","A7376-","T7377-","T7378-","G7379-","T7380-","G7381-","A7382-","T7383-","T7384-","T7385-","A7386-","C7387-","A7388-","C7389-","C7390-","A7391-","T7392-","A7393-","T7394-","T7395-","C7396-","G7397-","A7398-","C7399-","T7400-","C7401-","C7402-","C7403-","T7404-","T7405-","G7406-","T7407-","G7408-","T7409-","G7410-","T7411-","A7412-","A7413-","C7414-","G7415-","T7416-","T7417-","A7418-","G7419-","A7420-","A7421-","A7422-","T7423-","T7424-","C7425-","T7426-","A7427-","A7428-","A7429-","T7430-","C7431-","T7432-","A7433-","T7434-","A7435-","T7436-","T7437-","A7438-","T7439-","C7440-","T7441-","A7442-","T7443-","T7444-","A7445-","C7446-","A7447-","G7448-","C7449-","G7450-","T7451-","A7452-","A7453-","A7454-","A7455-","C7456-","A7457-","C7458-","A7459-","T7460-","T7461-","C7462-","A7463-","A7464-","T7465-","A7466-","T7467-","T7468-","G7469-","T7470-","A7471-","T7472-","T7473-","G7474-","T7475-","T7476-","A7477-","T7478-","T7479-","T7480-","T7481-","T7482-","A7483-","T7484-","A7485-","T7486-","T7487-","A7488-","T7489-","T7490-","T7491-","A7492-","C7493-","A7494-","C7495-","A7496-","A7497-","T7498-","T7499-","A7500-","A7501-","C7502-","A7503-","A7504-","T7505-","G7506-","T7507-","A7508-","T7509-","T7510-","A7511-","T7512-","T7513-","A7514-","G7515-","T7516-","T7517-","T7518-","A7519-","T7520-","A7521-","T7522-","T7523-","A7524-","C7525-","T7526-","G7527-","A7528-","A7529-","T7530-","T7531-","A7532-","A7533-","T7534-","A7535-","A7536-","T7537-","A7538-","T7539-","A7540-","A7541-","A7542-","A7543-","T7544-","T7545-","C7546-","C7547-","C7548-","A7549-","A7550-","T7551-","C7552-","T7553-","T7554-","G7555-","T7556-","C7557-","A7558-","T7559-","A7560-","A7561-","A7562-","C7563-","A7564-","C7565-","A7566-","A7567-","A7568-","A7569-","T7570-","C7571-","C7572-","A7573-","T7574-","T7575-","A7576-","A7577-","A7578-","A7579-","A7580-","T7581-","G7582-","T7583-","C7584-","G7585-","A7586-","T7587-","A7588-","A7589-","A7590-","A7591-","T7592-","A7593-","T7594-","C7595-","T7596-","G7597-","A7598-","T7599-","G7600-","T7601-","T7602-","G7603-","T7604-","T7605-","G7606-","T7607-","T7608-","C7609-","G7610-","C7611-","T7612-","G7613-","C7614-","T7615-","A7616-","T7617-","G7618-","A7619-","T7620-","A7621-","A7622-","T7623-","C7624-","A7625-","G7626-","A7627-","T7628-","C7629-","A7630-","T7631-","T7632-","A7633-","G7634-","C7635-","C7636-","G7637-","A7638-","T7639-","A7640-","G7641-","T7642-","G7643-","G7644-","T7645-","A7646-","A7647-","T7648-","G7649-","C7650-","T7651-","A7652-","T7653-","C7654-","G7655-","A7656-","A7657-","A7658-","C7659-","A7660-","A7661-","C7662-","A7663-","T7664-","C7665-","G7666-","C7667-","C7668-","A7669-","G7670-","A7671-","A7672-","A7673-","T7674-","T7675-","A7676-","C7677-","A7678-","A7679-","A7680-","C7681-","G7682-","C7683-","T7684-","A7685-","C7686-","A7687-","A7688-","C7689-","A7690-","G7691-","A7692-","T7693-","A7694-","T7695-","T7696-","C7697-","C7698-","A7699-","G7700-","C7701-","T7702-","A7703-","T7704-","C7705-","A7706-","G7707-","A7708-","T7709-","T7710-","A7711-","T7712-","G7713-","T7714-","G7715-","G7716-","T7717-","C7718-","C7719-","A7720-","G7721-","A7722-","G7723-","G7724-","G7725-","A7726-","G7727-","A7728-","T7729-","G7730-","G7731-","A7732-","T7733-","A7734-","T7735-","T7736-","G7737-","T7738-","T7739-","T7740-","A7741-","C7742-","A7743-","C7744-","G7745-","G7746-","T7747-","G7748-","A7749-","C7750-","T7751-","G7752-","T7753-","A7754-","T7755-","C7756-","C7757-","A7758-","C7759-","G7760-","C7761-","T7762-","A7763-","G7764-","A7765-","G7766-","A7767-","T7768-","A7769-","T7770-","C7771-","G7772-","A7773-","C7774-","G7775-","G7776-","T7777-","A7778-","T7779-","G7780-","T7781-","A7782-","T7783-","T7784-","G7785-","T7786-","A7787-","G7788-","A7789-","T7790-","G7791-","C7792-","T7793-","C7794-","T7795-","C7796-","A7797-","T7798-","G7799-","G7800-","T7801-","T7802-","A7803-","T7804-","A7805-","C7806-","A7807-","G7808-","G7809-","T7810-","A7811-","T7812-","T7813-","A7814-","G7815-","A7816-","T7817-","G7818-","T7819-","C7820-","A7821-","G7822-","C7823-","A7824-","T7825-","G7826-","T7827-","A7828-","G7829-","T7830-","A7831-","T7832-","T7833-","A7834-","G7835-","T7836-","A7837-","G7838-","A7839-","C7840-","T7841-","A7842-","T7843-","C7844-","A7845-","A7846-","C7847-","G7848-","T7849-","T7850-","C7851-","A7852-","G7853-","G7854-","A7855-","A7856-","A7857-","A7858-","C7859-","C7860-","A7861-","G7862-","A7863-","C7864-","A7865-","C7866-","T7867-","A7868-","C7869-","A7870-","A7871-","C7872-","A7873-","T7874-","C7875-","A7876-","T7877-","A7878-","T7879-","A7880-","T7881-","C7882-","C7883-","C7884-","A7885-","T7886-","C7887-","T7888-","C7889-","T7890-","A7891-","G7892-","G7893-","T7894-","A7895-","T7896-","T7897-","G7898-","T7899-","G7900-","C7901-","T7902-","T7903-","G7904-","T7905-","A7906-","T7907-","T7908-","A7909-","G7910-","T7911-","A7912-","G7913-","G7914-","C7915-","A7916-","T7917-","T7918-","A7919-","T7920-","T7921-","A7922-","T7923-","T7924-","A7925-","C7926-","G7927-","T7928-","G7929-","T7930-","T7931-","G7932-","T7933-","C7934-","T7935-","A7936-","T7937-","T7938-","A7939-","T7940-","C7941-","T7942-","G7943-","T7944-","T7945-","T7946-","A7947-","T7948-","A7949-","T7950-","G7951-","T7952-","T7953-","C7954-","A7955-","C7956-","T7957-","C7958-","G7959-","A7960-","A7961-","G7962-","A7963-","A7964-","C7965-","T7966-","A7967-","A7968-","A7969-","C7970-","T7971-","A7972-","C7973-","C7974-","T7975-","A7976-","T7977-","A7978-","C7979-","A7980-","A7981-","G7982-","A7983-","T7984-","A7985-","T7986-","G7987-","G7988-","T7989-","T7990-","G7991-","T7992-","G7993-","T7994-","T7995-","A7996-","T7997-","A7998-","T7999-","T8000-","T8001-","T8002-","T8003-","T8004-","A8005-","T8006-","A8007-","A8008-","A8009-","A8010-","T8011-","T8012-","T8013-","T8014-","T8015-","T8016-","T8017-","A8018-","T8019-","G8020-","A8021-","G8022-","T8023-","A8024-","T8025-","T8026-","T8027-","T8028-","T8029-","A8030-","C8031-","A8032-","A8033-","A8034-","A8035-","A8036-","T8037-","G8038-","T8039-","A8040-","T8041-","A8042-","T8043-","G8044-","T8045-","A8046-","T8047-","A8048-","A8049-","A8050-","A8051-","A8052-","A8053-","A8054-","A8055-","T8056-","A8057-","C8058-","T8059-","A8060-","A8061-","G8062-","T8063-","A8064-","T8065-","A8066-","C8067-","G8068-","A8069-","T8070-","G8071-","T8072-","A8073-","T8074-","C8075-","C8076-","T8077-","G8078-","T8079-","A8080-","T8081-","T8082-","A8083-","T8084-","T8085-","T8086-","G8087-","T8088-","A8089-","T8090-","T8091-","T8092-","A8093-","T8094-","C8095-","T8096-","A8097-","A8098-","A8099-","C8100-","A8101-","A8102-","T8103-","A8104-","C8105-","T8106-","T8107-","C8108-","T8109-","G8110-","C8111-","C8112-","T8113-","C8114-","T8115-","A8116-","G8117-","A8118-","T8119-","G8120-","G8121-","G8122-","A8123-","T8124-","A8125-","C8126-","A8127-","A8128-","A8129-","A8130-","A8131-","T8132-","T8133-","T8134-","T8135-","T8136-","T8137-","A8138-","T8139-","T8140-","T8141-","C8142-","A8143-","G8144-","C8145-","A8146-","T8147-","A8148-","T8149-","T8150-","A8151-","A8152-","A8153-","G8154-","T8155-","A8156-","A8157-","A8158-","A8159-","T8160-","C8161-","T8162-","A8163-","G8164-","T8165-","T8166-","A8167-","C8168-","C8169-","T8170-","T8171-","G8172-","A8173-","A8174-","A8175-","A8176-","T8177-","G8178-","A8179-","A8180-","T8181-","A8182-","C8183-","A8184-","G8185-","T8186-","G8187-","G8188-","G8189-","T8190-","G8191-","G8192-","T8193-","T8194-","C8195-","C8196-","G8197-","T8198-","A8199-","T8200-","C8201-","A8202-","C8203-","C8204-","A8205-","G8206-","T8207-","A8208-","A8209-","G8210-","A8211-","A8212-","C8213-","A8214-","T8215-","A8216-","A8217-","T8218-","A8219-","G8220-","T8221-","C8222-","G8223-","A8224-","A8225-","T8226-","A8227-","C8228-","A8229-","G8230-","T8231-","A8232-","T8233-","C8234-","C8235-","G8236-","A8237-","T8238-","T8239-","G8240-","A8241-","G8242-","A8243-","T8244-","T8245-","T8246-","T8247-","G8248-","C8249-","A8250-","T8251-","A8252-","C8253-","A8254-","A8255-","T8256-","A8257-","C8258-","T8259-","A8260-","G8261-","T8262-","C8263-","T8264-","A8265-","G8266-","A8267-","A8268-","A8269-","G8270-","A8271-","A8272-","A8273-","T8274-","T8275-","T8276-","G8277-","T8278-","A8279-","A8280-","T8281-","C8282-","A8283-","T8284-","C8285-","C8286-","T8287-","C8288-","T8289-","G8290-","T8291-","G8292-","A8293-","C8294-","A8295-","G8296-","G8297-","A8298-","G8299-","T8300-","C8301-","C8302-","A8303-","T8304-","A8305-","T8306-","A8307-","T8308-","C8309-","T8310-","G8311-","T8312-","A8313-","T8314-","C8315-","A8316-","T8317-","C8318-","G8319-","T8320-","C8321-","T8322-","A8323-","G8324-","T8325-","T8326-","T8327-","T8328-","T8329-","A8330-","T8331-","C8332-","A8333-","G8334-","T8335-","G8336-","T8337-","C8338-","C8339-","T8340-","A8341-","T8342-","G8343-","C8344-","T8345-","A8346-","T8347-","A8348-","T8349-","T8350-","C8351-","C8352-","T8353-","G8354-","T8355-","T8356-","A8357-","T8358-","C8359-","A8360-","T8361-","C8362-","A8363-","T8364-","T8365-","A8366-","G8367-","T8368-","T8369-","A8370-","A8371-","T8372-","G8373-","A8374-","A8375-","A8376-","A8377-","T8378-","A8379-","A8380-","C8381-","T8382-","C8383-","T8384-","C8385-","G8386-","T8387-","G8388-","C8389-","T8390-","T8391-","C8392-","A8393-","G8394-","A8395-","A8396-","A8397-","A8398-","G8399-","T8400-","C8401-","A8402-","A8403-","A8404-","T8405-","A8406-","T8407-","T8408-","G8409-","T8410-","A8411-","T8412-","C8413-","C8414-","A8415-","T8416-","A8417-","C8418-","A8419-","T8420-","A8421-","T8422-","A8423-","T8424-","C8425-","T8426-","C8427-","C8428-","A8429-","A8430-","A8431-","A8432-","C8433-","T8434-","A8435-","T8436-","C8437-","A8438-","C8439-","T8440-","T8441-","A8442-","T8443-","A8444-","C8445-","G8446-","T8447-","T8448-","T8449-","A8450-","T8451-","C8452-","T8453-","T8454-","T8455-","A8456-","A8457-","C8458-","G8459-","A8460-","A8461-","C8462-","A8463-","T8464-","A8465-","T8466-","A8467-","C8468-","C8469-","T8470-","A8471-","G8472-","A8473-","T8474-","G8475-","G8476-","T8477-","T8478-","A8479-","T8480-","T8481-","T8482-","A8483-","C8484-","T8485-","A8486-","A8487-","C8488-","A8489-","G8490-","A8491-","C8492-","A8493-","T8494-","T8495-","T8496-","T8497-","T8498-","T8499-","C8500-","A8501-","A8502-","G8503-","A8504-","T8505-","C8506-","T8507-","A8508-","T8509-","T8510-","G8511-","A8512-","C8513-","A8514-","A8515-","T8516-","A8517-","A8518-","C8519-","T8520-","C8521-","C8522-","T8523-","A8524-","T8525-","A8526-","G8527-","T8528-","T8529-","T8530-","C8531-","C8532-","A8533-","C8534-","A8535-","T8536-","C8537-","A8538-","A8539-","C8540-","C8541-","A8542-","A8543-","G8544-","T8545-","A8546-","A8547-","T8548-","G8549-","A8550-","T8551-","C8552-","A8553-","T8554-","C8555-","T8556-","A8557-","T8558-","T8559-","G8560-","T8561-","T8562-","A8563-","T8564-","A8565-","T8566-","A8567-","A8568-","C8569-","A8570-","A8571-","T8572-","A8573-","A8574-","C8575-","A8576-","T8577-","A8578-","A8579-","C8580-","T8581-","C8582-","T8583-","T8584-","T8585-","T8586-","C8587-","C8588-","A8589-","T8590-","T8591-","T8592-","T8593-","T8594-","A8595-","T8596-","C8597-","A8598-","G8599-","T8600-","A8601-","T8602-","C8603-","T8604-","A8605-","T8606-","A8607-","T8608-","C8609-","A8610-","A8611-","C8612-","G8613-","T8614-","C8615-","G8616-","T8617-","T8618-","G8619-","T8620-","A8621-","G8622-","T8623-","G8624-","A8625-","A8626-","T8627-","A8628-","G8629-","T8630-","A8631-","G8632-","T8633-","C8634-","A8635-","T8636-","T8637-","G8638-","A8639-","T8640-","C8641-","T8642-","A8643-","T8644-","T8645-","A8646-","T8647-","A8648-","T8649-","G8650-","A8651-","A8652-","A8653-","C8654-","G8655-","G8656-","A8657-","T8658-","A8659-","T8660-","G8661-","T8662-","C8663-","T8664-","A8665-","G8666-","T8667-","T8668-","A8669-","A8670-","T8671-","A8672-","T8673-","T8674-","T8675-","T8676-","C8677-","T8678-","T8679-","T8680-","G8681-","A8682-","T8683-","T8684-","T8685-","A8686-","A8687-","A8688-","G8689-","T8690-","C8691-","T8692-","A8693-","T8694-","A8695-","G8696-","T8697-","C8698-","T8699-","T8700-","T8701-","A8702-","C8703-","A8704-","A8705-","A8706-","C8707-","A8708-","T8709-","A8710-","A8711-","T8712-","A8713-","T8714-","C8715-","C8716-","T8717-","T8718-","A8719-","T8720-","C8721-","C8722-","G8723-","A8724-","C8725-","T8726-","T8727-","T8728-","A8729-","T8730-","A8731-","T8732-","T8733-","T8734-","C8735-","C8736-","T8737-","G8738-","T8739-","A8740-","G8741-","G8742-","G8743-","T8744-","G8745-","G8746-","C8747-","A8748-","T8749-","A8750-","A8751-","T8752-","T8753-","T8754-","T8755-","A8756-","T8757-","T8758-","C8759-","T8760-","G8761-","C8762-","C8763-","T8764-","C8765-","C8766-","A8767-","C8768-","A8769-","A8770-","T8771-","C8772-","A8773-","G8774-","T8775-","G8776-","T8777-","T8778-","T8779-","C8780-","C8781-","A8782-","A8783-","A8784-","T8785-","A8786-","T8787-","A8788-","T8789-","T8790-","A8791-","C8792-","T8793-","A8794-","G8795-","A8796-","C8797-","A8798-","A8799-","T8800-","A8801-","T8802-","T8803-","C8804-","C8805-","A8806-","T8807-","A8808-","T8809-","A8810-","G8811-","T8812-","T8813-","A8814-","T8815-","T8816-","A8817-","G8818-","T8819-","T8820-","A8821-","A8822-","G8823-","G8824-","G8825-","A8826-","C8827-","C8828-","C8829-","A8830-","A8831-","T8832-","T8833-","A8834-","G8835-","A8836-","A8837-","C8838-","A8839-","C8840-","G8841-","T8842-","A8843-","C8844-","G8845-","C8846-","G8847-","C8848-","T8849-","T8850-","A8851-","T8852-","T8853-","C8854-","A8855-","T8856-","C8857-","A8858-","T8859-","T8860-","T8861-","G8862-","G8863-","A8864-","T8865-","C8866-","G8867-","T8868-","A8869-","T8870-","T8871-","T8872-","C8873-","A8874-","T8875-","A8876-","A8877-","A8878-","A8879-","G8880-","T8881-","T8882-","A8883-","T8884-","T8885-","A8886-","T8887-","G8888-","T8889-","T8890-","A8891-","T8892-","A8893-","G8894-","A8895-","T8896-","G8897-","T8898-","C8899-","A8900-","A8901-","C8902-","A8903-","C8904-","A8905-","T8906-","T8907-","C8908-","T8909-","A8910-","C8911-","A8912-","T8913-","T8914-","T8915-","T8916-","T8917-","T8918-","T8919-","A8920-","A8921-","T8922-","T8923-","G8924-","T8925-","C8926-","T8927-","A8928-","T8929-","A8930-","T8931-","A8932-","G8933-","T8934-","A8935-","T8936-","T8937-","T8938-","T8939-","T8940-","C8941-","T8942-","G8943-","A8944-","T8945-","A8946-","T8947-","T8948-","T8949-","T8950-","C8951-","T8952-","A8953-","T8954-","A8955-","A8956-","T8957-","A8958-","T8959-","C8960-","A8961-","G8962-","A8963-","A8964-","T8965-","T8966-","G8967-","T8968-","C8969-","T8970-","T8971-","C8972-","C8973-","A8974-","T8975-","A8976-","G8977-","G8978-","A8979-","A8980-","G8981-","T8982-","T8983-","G8984-","T8985-","A8986-","T8987-","A8988-","C8989-","T8990-","A8991-","T8992-","T8993-","C8994-","G8995-","G8996-","A8997-","A8998-","T8999-","C9000-","A9001-","G9002-","T9003-","T9004-","A9005-","C9006-","A9007-","T9008-","G9009-","T9010-","T9011-","T9012-","A9013-","A9014-","A9015-","T9016-","A9017-","A9018-","T9019-","T9020-","C9021-","T9022-","C9023-","T9024-","G9025-","A9026-","T9027-","G9028-","T9029-","C9030-","A9031-","T9032-","T9033-","C9034-","C9035-","T9036-","T9037-","A9038-","T9039-","A9040-","C9041-","A9042-","A9043-","T9044-","C9045-","A9046-","A9047-","A9048-","T9049-","T9050-","C9051-","A9052-","T9053-","T9054-","A9055-","T9056-","T9057-","A9058-","A9059-","A9060-","C9061-","A9062-","G9063-","T9064-","T9065-","T9066-","A9067-","A9068-","T9069-","A9070-","G9071-","T9072-","C9073-","T9074-","G9075-","T9076-","A9077-","G9078-","A9079-","C9080-","C9081-","T9082-","T9083-","T9084-","A9085-","T9086-","C9087-","G9088-","T9089-","C9090-","G9091-","T9092-","A9093-","C9094-","A9095-","T9096-","A9097-","T9098-","C9099-","C9100-","A9101-","T9102-","T9103-","G9104-","T9105-","C9106-","T9107-","T9108-","A9109-","T9110-","T9111-","A9112-","G9113-","T9114-","T9115-","A9116-","C9117-","G9118-","C9119-","T9120-","T9121-","A9122-","T9123-","T9124-","T9125-","T9126-","T9127-","A9128-","T9129-","G9130-","G9131-","G9132-","T9133-","T9134-","T9135-","T9136-","A9137-","C9138-","G9139-","T9140-","T9141-","G9142-","C9143-","T9144-","T9145-","T9146-","A9147-","T9148-","T9149-","A9150-","T9151-","A9152-","T9153-","T9154-","T9155-","T9156-","A9157-","T9158-","A9159-","A9160-","T9161-","A9162-","A9163-","T9164-","G9165-","A9166-","T9167-","T9168-","G9169-","T9170-","T9171-","T9172-","G9173-","A9174-","C9175-","A9176-","A9177-","T9178-","G9179-","T9180-","C9181-","G9182-","T9183-","A9184-","G9185-","T9186-","A9187-","T9188-","A9189-","G9190-","A9191-","T9192-","A9193-","T9194-","A9195-","T9196-","T9197-","A9198-","T9199-","T9200-","A9201-","G9202-","A9203-","G9204-","G9205-","A9206-","G9207-","G9208-","T9209-","A9210-","T9211-","A9212-","A9213-","T9214-","T9215-","A9216-","T9217-","A9218-","A9219-","A9220-","A9221-","A9222-","G9223-","T9224-","T9225-","T9226-","C9227-","T9228-","G9229-","A9230-","G9231-","T9232-","A9233-","C9234-","G9235-","A9236-","T9237-","G9238-","T9239-","T9240-","A9241-","T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","C9257-","A9258-","T9259-","T9260-","A9261-","A9262-","C9263-","A9264-","T9265-","C9266-","A9267-","T9268-","A9269-","C9270-","A9271-","T9272-","C9273-","A9274-","A9275-","T9276-","T9277-","A9278-","A9279-","C9280-","T9281-","A9282-","C9283-","A9284-","T9285-","T9286-","C9287-","T9288-","T9289-","A9290-","T9291-","A9292-","A9293-","C9294-","A9295-","T9296-","T9297-","G9298-","T9299-","A9300-","A9301-","T9302-","C9303-","A9304-","A9305-","A9306-","A9307-","G9308-","A9309-","A9310-","T9311-","T9312-","G9313-","C9314-","A9315-","A9316-","T9317-","T9318-","T9319-","T9320-","G9321-","A9322-","T9323-","G9324-","T9325-","A9326-","T9327-","A9328-","A9329-","C9330-","A9331-","A9332-","C9333-","T9334-","G9335-","T9336-","C9337-","A9338-","A9339-","T9340-","G9341-","G9342-","A9343-","A9344-","T9345-","T9346-","G9347-","T9348-","A9349-","T9350-","A9351-","T9352-","T9353-","A9354-","C9355-","A9356-","A9357-","A9358-","T9359-","T9360-","A9361-","C9362-","G9363-","G9364-","T9365-","A9366-","T9367-","G9368-","T9369-","T9370-","G9371-","T9372-","A9373-","A9374-","C9375-","A9376-","A9377-","C9378-","A9379-","A9380-","A9381-","T9382-","A9383-","C9384-","C9385-","G9386-","A9387-","T9388-","C9389-","G9390-","G9391-","T9392-","A9393-","A9394-","T9395-","T9396-","G9397-","T9398-","C9399-","T9400-","C9401-","T9402-","G9403-","C9404-","C9405-","G9406-","C9407-","T9408-","G9409-","T9410-","A9411-","A9412-","T9413-","A9414-","G9415-","A9416-","A9417-","T9418-","T9419-","A9420-","A9421-","T9422-","T9423-","A9424-","T9425-","A9426-","T9427-","A9428-","T9429-","C9430-","T9431-","A9432-","T9433-","T9434-","A9435-","C9436-","A9437-","C9438-","C9439-","G9440-","G9441-","C9442-","C9443-","T9444-","T9445-","G9446-","T9447-","A9448-","T9449-","C9450-","A9451-","T9452-","A9453-","A9454-","T9455-","A9456-","A9457-","A9458-","G9459-","T9460-","T9461-","G9462-","T9463-","G9464-","G9465-","T9466-","A9467-","G9468-","T9469-","A9470-","T9471-","G9472-","A9473-","T9474-","C9475-","T9476-","C9477-","C9478-","A9479-","T9480-","A9481-","T9482-","T9483-","T9484-","A9485-","T9486-","A9487-","A9488-","T9489-","T9490-","T9491-","A9492-","G9493-","T9494-","A9495-","C9496-","T9497-","T9498-","T9499-","G9500-","T9501-","A9502-","T9503-","T9504-","T9505-","A9506-","G9507-","T9508-","T9509-","T9510-","T9511-","T9512-","T9513-","T9514-","G9515-","G9516-","A9517-","A9518-","T9519-","C9520-","A9521-","T9522-","A9523-","A9524-","A9525-","A9526-","A9527-","A9528-","A9529-","G9530-","T9531-","T9532-","T9533-","T9534-","A9535-","C9536-","T9537-","A9538-","A9539-","T9540-","T9541-","T9542-","A9543-","A9544-","A9545-","A9546-","T9547-","T9548-","T9549-","A9550-","A9551-","A9552-","A9553-","A9554-","G9555-","T9556-","A9557-","T9558-","T9559-","T9560-","A9561-","C9562-","A9563-","T9564-","T9565-","T9566-","T9567-","T9568-","C9569-","A9570-","C9571-","T9572-","G9573-","T9574-","T9575-","T9576-","A9577-","G9578-","T9579-","C9580-","G9581-","C9582-","G9583-","G9584-","A9585-","T9586-","A9587-","T9588-","G9589-","G9590-","A9591-","A9592-","T9593-","T9594-","C9595-","G9596-","A9597-","T9598-","C9599-","C9600-","T9601-","G9602-","T9603-","C9604-","A9605-","A9606-","A9607-","A9608-","T9609-","C9610-","A9611-","A9612-","T9613-","A9614-","C9615-","A9616-","T9617-","C9618-","A9619-","T9620-","C9621-","T9622-","A9623-","T9624-","A9625-","G9626-","A9627-","T9628-","C9629-","A9630-","T9631-","G9632-","T9633-","A9634-","A9635-","C9636-","A9637-","A9638-","T9639-","A9640-","T9641-","T9642-","A9643-","C9644-","A9645-","A9646-","T9647-","A9648-","C9649-","A9650-","T9651-","A9652-","G9653-","A9654-","T9655-","G9656-","A9657-","A9658-","C9659-","C9660-","A9661-","A9662-","A9663-","T9664-","G9665-","A9666-","T9667-","A9668-","T9669-","A9670-","A9671-","G9672-","A9673-","C9674-","T9675-","A9676-","A9677-","C9678-","A9679-","G9680-","T9681-","A9682-","T9683-","G9684-","C9685-","A9686-","T9687-","T9688-","A9689-","T9690-","C9691-","C9692-","G9693-","A9694-","A9695-","A9696-","T9697-","G9698-","T9699-","T9700-","A9701-","A9702-","T9703-","A9704-","A9705-","C9706-","A9707-","T9708-","T9709-","A9710-","C9711-","A9712-","T9713-","A9714-","T9715-","T9716-","A9717-","T9718-","A9719-","T9720-","C9721-","A9722-","A9723-","T9724-","A9725-","T9726-","C9727-","A9728-","C9729-","A9730-","A9731-","A9732-","A9733-","A9734-","T9735-","A9736-","A9737-","A9738-","T9739-","C9740-","C9741-","A9742-","C9743-","A9744-","T9745-","T9746-","T9747-","G9748-","G9749-","C9750-","T9751-","A9752-","A9753-","T9754-","C9755-","G9756-","A9757-","T9758-","T9759-","T9760-","C9761-","G9762-","G9763-","G9764-","C9765-","T9766-","T9767-","G9768-","G9769-","A9770-","A9771-","A9772-","A9773-","A9774-","A9775-","C9776-","G9777-","T9778-","A9779-","T9780-","C9781-","G9782-","C9783-","C9784-","G9785-","G9786-","A9787-","A9788-","G9789-","G9790-","G9791-","A9792-","C9793-","T9794-","A9795-","T9796-","A9797-","T9798-","G9799-","A9800-","C9801-","T9802-","A9803-","A9804-","C9805-","T9806-","T9807-","A9808-","T9809-","C9810-","T9811-","A9812-","G9813-","A9814-","G9815-","A9816-","T9817-","A9818-","C9819-","A9820-","G9821-","G9822-","A9823-","A9824-","T9825-","A9826-","C9827-","A9828-","A9829-","C9830-","A9831-","A9832-","T9833-","C9834-","A9835-","A9836-","A9837-","A9838-","C9839-","T9840-","T9841-","A9842-","C9843-","T9844-","G9845-","A9846-","A9847-","A9848-","C9849-","T9850-","A9851-","T9852-","A9853-","C9854-","G9855-","T9856-","A9857-","A9858-","C9859-","T9860-","G9861-","T9862-","C9863-","A9864-","A9865-","A9866-","A9867-","A9868-","A9869-","A9870-","T9871-","A9872-","A9873-","A9874-","A9875-","A9876-","C9877-","A9878-","T9879-","A9880-","T9881-","A9882-","T9883-","G9884-","G9885-","T9886-","C9887-","T9888-","A9889-","T9890-","A9891-","T9892-","A9893-","T9894-","A9895-","C9896-","A9897-","C9898-","T9899-","A9900-","C9901-","A9902-","A9903-","T9904-","T9905-","T9906-","A9907-","G9908-","T9909-","T9910-","A9911-","T9912-","T9913-","A9914-","A9915-","T9916-","G9917-","T9918-","G9919-","G9920-","T9921-","T9922-","A9923-","T9924-","T9925-","G9926-","A9927-","T9928-","T9929-","G9930-","G9931-","A9932-","T9933-","A9934-","A9935-","C9936-","C9937-","G9938-","A9939-","T9940-","G9941-","T9942-","G9943-","A9944-","T9945-","T9946-","G9947-","T9948-","T9949-","C9950-","A9951-","A9952-","T9953-","C9954-","A9955-","A9956-","T9957-","A9958-","T9959-","T9960-","A9961-","A9962-","G9963-","A9964-","G9965-","G9966-","G9967-","T9968-","T9969-","G9970-","G9971-","T9972-","A9973-","A9974-","A9975-","T9976-","T9977-","G9978-","G9979-","T9980-","A9981-","C9982-","A9983-","T9984-","A9985-","G9986-","C9987-","T9988-","A9989-","A9990-","T9991-","A9992-","A9993-","T9994-","A9995-","C9996-","A9997-","T9998-","A9999-","T10000-","A10001-","C10002-","T10003-","C10004-","C10005-","A10006-","A10007-","A10008-","T10009-","A10010-","C10011-","A10012-","C10013-","C10014-","C10015-","A10016-","A10017-","T10018-","A10019-","A10020-","T10021-","A10022-","C10023-","T10024-","A10025-","C10026-","A10027-","A10028-","C10029-","C10030-","A10031-","T10032-","T10033-","T10034-","C10035-","T10036-","G10037-","A10038-","G10039-","T10040-","T10041-","G10042-","G10043-","A10044-","T10045-","A10046-","T10047-","C10048-","A10049-","T10050-","C10051-","A10052-","A10053-","A10054-","A10055-","T10056-","A10057-","C10058-","T10059-","G10060-","G10061-","A10062-","T10063-","A10064-","A10065-","A10066-","T10067-","A10068-","C10069-","G10070-","A10071-","G10072-","G10073-","A10074-","C10075-","A10076-","T10077-","G10078-","T10079-","A10080-","T10081-","A10082-","G10083-","A10084-","G10085-","T10086-","A10087-","A10088-","G10089-","T10090-","A10091-","A10092-","A10093-","G10094-","A10095-","A10096-","A10097-","A10098-","A10099-","G10100-","A10101-","A10102-","T10103-","G10104-","T10105-","G10106-","G10107-","A10108-","A10109-","T10110-","T10111-","T10112-","G10113-","C10114-","T10115-","A10116-","T10117-","G10118-","A10119-","A10120-","G10121-","T10122-","T10123-","G10124-","T10125-","T10126-","T10127-","A10128-","C10129-","T10130-","C10131-","A10132-","A10133-","A10134-","A10135-","C10136-","G10137-","A10138-","T10139-","T10140-","A10141-","G10142-","A10143-","A10144-","A10145-","A10146-","C10147-","G10148-","A10149-","T10150-","A10151-","G10152-","A10153-","T10154-","A10155-","C10156-","T10157-","T10158-","T10159-","G10160-","G10161-","T10162-","T10163-","T10164-","A10165-","T10166-","T10167-","G10168-","G10169-","A10170-","T10171-","T10172-","C10173-","G10174-","T10175-","G10176-","T10177-","A10178-","A10179-","T10180-","C10181-","A10182-","T10183-","A10184-","T10185-","A10186-","T10187-","T10188-","T10189-","T10190-","G10191-","C10192-","A10193-","T10194-","A10195-","A10196-","C10197-","A10198-","T10199-","G10200-","T10201-","A10202-","T10203-","C10204-","A10205-","A10206-","T10207-","A10208-","T10209-","A10210-","T10211-","G10212-","G10213-","C10214-","A10215-","T10216-","A10217-","G10218-","A10219-","A10220-","C10221-","A10222-","C10223-","G10224-","A10225-","A10226-","G10227-","A10228-","G10229-","A10230-","A10231-","A10232-","C10233-","C10234-","G10235-","G10236-","T10237-","G10238-","C10239-","G10240-","T10241-","C10242-","A10243-","G10244-","A10245-","T10246-","A10247-","A10248-","T10249-","T10250-","G10251-","T10252-","C10253-","C10254-","T10255-","A10256-","T10257-","A10258-","T10259-","G10260-","C10261-","C10262-","G10263-","T10264-","A10265-","C10266-","A10267-","C10268-","G10269-","T10270-","T10271-","T10272-","T10273-","A10274-","A10275-","A10276-","A10277-","A10278-","A10279-","A10280-","T10281-","A10282-","A10283-","C10284-","A10285-","A10286-","T10287-","G10288-","A10289-","G10290-","C10291-","A10292-","A10293-","G10294-","T10295-","T10296-","C10297-","T10298-","A10299-","T10300-","A10301-","A10302-","G10303-","C10304-","T10305-","A10306-","G10307-","T10308-","T10309-","A10310-","A10311-","C10312-","T10313-","A10314-","A10315-","T10316-","A10317-","A10318-","A10319-","T10320-","A10321-","A10322-","A10323-","A10324-","A10325-","G10326-","T10327-","T10328-","T10329-","A10330-","A10331-","T10332-","T10333-","A10334-","T10335-","C10336-","G10337-","A10338-","C10339-","G10340-","A10341-","T10342-","A10343-","T10344-","A10345-","T10346-","G10347-","T10348-","C10349-","G10350-","T10351-","T10352-","A10353-","T10354-","T10355-","T10356-","T10357-","T10358-","C10359-","T10360-","C10361-","T10362-","C10363-","A10364-","T10365-","A10366-","T10367-","G10368-","A10369-","A10370-","A10371-","G10372-","A10373-","T10374-","T10375-","A10376-","A10377-","T10378-","T10379-","T10380-","G10381-","A10382-","T10383-","T10384-","C10385-","T10386-","A10387-","A10388-","T10389-","A10390-","T10391-","A10392-","A10393-","T10394-","C10395-","T10396-","T10397-","C10398-","A10399-","G10400-","T10401-","A10402-","T10403-","T10404-","G10405-","G10406-","A10407-","T10408-","G10409-","A10410-","A10411-","T10412-","C10413-","T10414-","C10415-","A10416-","A10417-","T10418-","T10419-","C10420-","A10421-","A10422-","A10423-","T10424-","T10425-","A10426-","A10427-","T10428-","T10429-","C10430-","C10431-","A10432-","T10433-","T10434-","A10435-","G10436-","A10437-","T10438-","T10439-","A10440-","G10441-","A10442-","T10443-","T10444-","A10445-","G10446-","A10447-","T10448-","T10449-","A10450-","G10451-","A10452-","T10453-","C10454-","A10455-","T10456-","A10457-","A10458-","A10459-","T10460-","A10461-","A10462-","A10463-","A10464-","A10465-","T10466-","A10467-","G10468-","T10469-","A10470-","G10471-","C10472-","A10473-","C10474-","G10475-","C10476-","A10477-","C10478-","T10479-","A10480-","C10481-","T10482-","T10483-","C10484-","A10485-","G10486-","C10487-","C10488-","A10489-","A10490-","A10491-","T10492-","A10493-","T10494-","T10495-","C10496-","T10497-","T10498-","T10499-","T10500-","T10501-","T10502-","G10503-","A10504-","A10505-","A10506-","C10507-","G10508-","C10509-","C10510-","A10511-","T10512-","C10513-","T10514-","A10515-","G10516-","C10517-","G10518-","T10519-","A10520-","A10521-","T10522-","G10523-","A10524-","G10525-","A10526-","A10527-","C10528-","A10529-","C10530-","A10531-","A10532-","G10533-","T10534-","G10535-","A10536-","A10537-","C10538-","C10539-","T10540-","A10541-","T10542-","A10543-","A10544-","T10545-","G10546-","A10547-","G10548-","C10549-","A10550-","A10551-","A10552-","T10553-","T10554-","T10555-","A10556-","T10557-","T10558-","A10559-","G10560-","T10561-","A10562-","T10563-","C10564-","G10565-","G10566-","T10567-","T10568-","A10569-","C10570-","A10571-","T10572-","G10573-","A10574-","A10575-","G10576-","G10577-","A10578-","C10579-","T10580-","T10581-","T10582-","A10583-","C10584-","G10585-","T10586-","A10587-","G10588-","A10589-","G10590-","T10591-","G10592-","G10593-","T10594-","G10595-","A10596-","T10597-","T10598-","C10599-","C10600-","T10601-","C10602-","C10603-","A10604-","T10605-","C10606-","T10607-","G10608-","T10609-","G10610-","G10611-","T10612-","A10613-","C10614-","G10615-","A10616-","A10617-","C10618-","G10619-","G10620-","T10621-","T10622-","T10623-","C10624-","A10625-","T10626-","C10627-","T10628-","T10629-","C10630-","T10631-","T10632-","T10633-","G10634-","A10635-","T10636-","G10637-","C10638-","C10639-","A10640-","C10641-","C10642-","A10643-","C10644-","C10645-","C10646-","A10647-","G10648-","A10649-","T10650-","G10651-","T10652-","T10653-","C10654-","T10655-","A10656-","T10657-","A10658-","A10659-","A10660-","C10661-","T10662-","T10663-","G10664-","G10665-","T10666-","A10667-","T10668-","C10669-","C10670-","T10671-","C10672-","G10673-","T10674-","C10675-","C10676-","G10677-","A10678-","T10679-","T10680-","T10681-","C10682-","A10683-","T10684-","A10685-","T10686-","C10687-","A10688-","T10689-","T10690-","T10691-","G10692-","C10693-","C10694-","A10695-","A10696-","C10697-","C10698-","A10699-","A10700-","T10701-","A10702-","C10703-","A10704-","T10705-","A10706-","T10707-","A10708-","G10709-","C10710-","T10711-","A10712-","A10713-","A10714-","C10715-","C10716-","C10717-","A10718-","G10719-","G10720-","C10721-","A10722-","T10723-","A10724-","C10725-","G10726-","T10727-","T10728-","C10729-","C10730-","A10731-","C10732-","A10733-","C10734-","A10735-","T10736-","C10737-","C10738-","G10739-","G10740-","A10741-","A10742-","C10743-","A10744-","A10745-","T10746-","G10747-","A10748-","A10749-","A10750-","T10751-","T10752-","C10753-","T10754-","C10755-","C10756-","A10757-","G10758-","A10759-","A10760-","G10761-","A10762-","T10763-","G10764-","T10765-","T10766-","A10767-","C10768-","A10769-","A10770-","T10771-","G10772-","G10773-","C10774-","T10775-","A10776-","G10777-","A10778-","T10779-","T10780-","T10781-","G10782-","G10783-","A10784-","C10785-","A10786-","T10787-","T10788-","T10789-","G10790-","G10791-","T10792-","T10793-","T10794-","C10795-","A10796-","A10797-","C10798-","C10799-","G10800-","C10801-","G10802-","T10803-","T10804-","A10805-","A10806-","C10807-","A10808-","T10809-","A10810-","T10811-","G10812-","A10813-","G10814-","T10815-","G10816-","A10817-","A10818-","C10819-","A10820-","C10821-","A10822-","C10823-","C10824-","C10825-","A10826-","T10827-","A10828-","C10829-","A10830-","T10831-","G10832-","A10833-","A10834-","A10835-","G10836-","C10837-","G10838-","A10839-","T10840-","G10841-","A10842-","G10843-","A10844-","A10845-","A10846-","T10847-","A10848-","G10849-","G10850-","A10851-","T10852-","T10853-","C10854-","T10855-","C10856-","A10857-","T10858-","C10859-","T10860-","T10861-","G10862-","C10863-","C10864-","A10865-","A10866-","A10867-","A10868-","T10869-","A10870-","T10871-","C10872-","A10873-","C10874-","T10875-","A10876-","T10877-","A10878-","A10879-","A10880-","A10881-","A10882-","A10883-","T10884-","T10885-","T10886-","A10887-","T10888-","T10889-","T10890-","A10891-","T10892-","C10893-","A10894-","A10895-","T10896-","T10897-","T10898-","T10899-","A10900-","A10901-","A10902-","G10903-","G10904-","T10905-","A10906-","T10907-","A10908-","A10909-","A10910-","A10911-","A10912-","A10913-","A10914-","T10915-","A10916-","C10917-","T10918-","T10919-","A10920-","T10921-","T10922-","G10923-","T10924-","T10925-","G10926-","C10927-","T10928-","C10929-","G10930-","A10931-","A10932-","T10933-","A10934-","T10935-","T10936-","T10937-","T10938-","G10939-","T10940-","A10941-","T10942-","T10943-","T10944-","G10945-","A10946-","T10947-","G10948-","G10949-","T10950-","A10951-","T10952-","A10953-","C10954-","G10955-","G10956-","A10957-","A10958-","G10959-","A10960-","T10961-","T10962-","A10963-","G10964-","A10965-","A10966-","A10967-","T10968-","G10969-","T10970-","A10971-","G10972-","G10973-","T10974-","A10975-","T10976-","T10977-","A10978-","T10979-","C10980-","A10981-","T10982-","C10983-","A10984-","A10985-","C10986-","T10987-","G10988-","A10989-","T10990-","T10991-","T10992-","T10993-","A10994-","T10995-","G10996-","A10997-","T10998-","G10999-","G11000-","T11001-","T11002-","T11003-","T11004-","A11005-","T11006-","G11007-","A11008-","A11009-","T11010-","T11011-","T11012-","T11013-","A11014-","T11015-","T11016-","A11017-","T11018-","G11019-","C11020-","T11021-","T11022-","C11023-","A11024-","C11025-","T11026-","A11027-","T11028-","T11029-","G11030-","C11031-","A11032-","T11033-","C11034-","G11035-","G11036-","A11037-","A11038-","A11039-","T11040-","A11041-","A11042-","T11043-","A11044-","T11045-","C11046-","A11047-","T11048-","A11049-","T11050-","G11051-","C11052-","T11053-","T11054-","C11055-","C11056-","A11057-","C11058-","G11059-","T11060-","A11061-","T11062-","A11063-","T11064-","T11065-","T11066-","T11067-","A11068-","T11069-","T11070-","T11071-","T11072-","G11073-","T11074-","T11075-","T11076-","T11077-","G11078-","A11079-","C11080-","T11081-","C11082-","A11083-","T11084-","A11085-","A11086-","T11087-","A11088-","C11089-","G11090-","C11091-","A11092-","C11093-","G11094-","T11095-","A11096-","A11097-","T11098-","T11099-","C11100-","T11101-","G11102-","G11103-","A11104-","T11105-","T11106-","A11107-","T11108-","T11109-","G11110-","G11111-","C11112-","A11113-","T11114-","A11115-","T11116-","C11117-","G11118-","A11119-","T11120-","G11121-","A11122-","A11123-","T11124-","A11125-","A11126-","T11127-","T11128-","T11129-","T11130-","A11131-","G11132-","C11133-","T11134-","C11135-","C11136-","A11137-","T11138-","G11139-","C11140-","T11141-","C11142-","A11143-","G11144-","T11145-","A11146-","A11147-","A11148-","T11149-","A11150-","T11151-","T11152-","A11153-","A11154-","T11155-","G11156-","A11157-","G11158-","A11159-","A11160-","C11161-","A11162-","T11163-","A11164-","G11165-","T11166-","G11167-","T11168-","T11169-","G11170-","C11171-","C11172-","T11173-","C11174-","C11175-","T11176-","A11177-","C11178-","C11179-","A11180-","T11181-","T11182-","A11183-","T11184-","T11185-","T11186-","T11187-","T11188-","T11189-","T11190-","C11191-","A11192-","T11193-","C11194-","T11195-","C11196-","A11197-","T11198-","T11199-","C11200-","A11201-","A11202-","T11203-","T11204-","C11205-","T11206-","T11207-","G11208-","A11209-","T11210-","T11211-","G11212-","C11213-","A11214-","G11215-","A11216-","G11217-","A11218-","T11219-","C11220-","T11221-","A11222-","T11223-","A11224-","T11225-","A11226-","A11227-","T11228-","C11229-","A11230-","T11231-","T11232-","A11233-","T11234-","A11235-","G11236-","C11237-","G11238-","T11239-","T11240-","G11241-","A11242-","C11243-","T11244-","T11245-","A11246-","T11247-","G11248-","G11249-","A11250-","C11251-","T11252-","C11253-","T11254-","G11255-","G11256-","A11257-","A11258-","T11259-","C11260-","T11261-","T11262-","A11263-","G11264-","A11265-","C11266-","G11267-","A11268-","T11269-","G11270-","T11271-","A11272-","C11273-","A11274-","G11275-","T11276-","C11277-","A11278-","T11279-","C11280-","T11281-","A11282-","T11283-","A11284-","A11285-","T11286-","C11287-","A11288-","T11289-","G11290-","G11291-","T11292-","A11293-","T11294-","A11295-","T11296-","T11297-","T11298-","A11299-","A11300-","T11301-","A11302-","C11303-","A11304-","T11305-","T11306-","G11307-","T11308-","T11309-","T11310-","T11311-","A11312-","T11313-","A11314-","G11315-","C11316-","A11317-","T11318-","A11319-","G11320-","G11321-","C11322-","A11323-","T11324-","T11325-","A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","C11727T","C39139T","-173314A","-173315T","-173316A","-173317T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A185259-","G185260-","A185261-","A185262-","T185263-","G185264-","T185265-","T185266-","T185267-","G185268-","C185269-","C185270-","A185271-","C185272-","A185273-","T185274-","T185275-","G185276-","G185277-","C185278-","T185279-","A185280-","G185281-","A185282-","G185283-","G185284-","A185285-","A185286-","T185287-","G185288-","C185289-","C185290-","G185291-","T185292-","T185293-","T185294-","A185295-","G185296-","A185297-","T185298-","C185299-","A185300-","A185301-","C185302-","G185303-","T185304-","A185305-","T185306-","T185307-","G185308-","C185309-","G185310-","A185311-","T185312-","A185313-","A185314-","C185315-","A185316-","G185317-","A185318-","C185319-","G185320-","A185321-","C185322-","G185323-","A185324-","T185325-","C185326-","A185327-","G185328-","G185329-","T185330-","T185331-","G185332-","T185333-","T185334-","A185335-","T185336-","T185337-","A185338-","T185339-","G185340-","C185341-","A185342-","G185343-","G185344-","A185345-","A185346-","T185347-","A185348-","C185349-","C185350-","A185351-","T185352-","T185353-","T185354-","C185355-","A185356-","T185357-","G185358-","A185359-","A185360-","G185361-","A185362-","T185363-","A185364-","G185365-","T185366-","G185367-","T185368-","A185369-","G185370-","A185371-","A185372-","A185373-","C185374-","A185375-","G185376-","A185377-","T185378-","A185379-","T185380-","A185381-","C185382-","A185383-","T185384-","T185385-","A185386-","T185387-","G185388-","G185389-","A185390-","C185391-","C185392-","A185393-","G185394-","A185395-","A185396-","A185397-","T185398-","A185399-","A185400-","T185401-","G185402-","T185403-","T185404-","A185405-","A185406-","A185407-","G185408-","G185409-","A185410-","A185411-","A185412-","C185413-","A185414-","T185415-","A185416-","T185417-","G185418-","A185419-","C185420-","A185421-","T185422-","A185423-","A185424-","A185425-","C185426-","A185427-","G185428-","T185429-","A185430-","T185431-","T185432-","G185433-","A185434-","C185435-","C185436-","C185437-","A185438-","C185439-","G185440-","A185441-","G185442-","T185443-","T185444-","A185445-","T185446-","A185447-","A185448-","C185449-","A185450-","A185451-","A185452-","G185453-","T185454-","C185455-","A185456-","A185457-","A185458-","G185459-","A185460-","C185461-","C185462-","C185463-","A185464-","T185465-","T185466-","T185467-","T185468-","C185469-","C185470-","T185471-","G185472-","C185473-","T185474-","C185475-","C185476-","A185477-","T185478-","T185479-","G185480-","A185481-","G185482-","T185483-","G185484-","T185485-","A185486-","A185487-","A185488-","A185489-","T185490-","T185491-","C185492-","A185493-","T185494-","G185495-","G185496-","T185497-","T185498-","G185499-","A185500-","C185501-","A185502-","A185503-","T185504-","T185505-","T185506-","A185507-","G185508-","G185509-","A185510-","A185511-","A185512-","T185513-","G185514-","G185515-","A185516-","T185517-","A185518-","T185519-","G185520-","A185521-","C185522-","A185523-","A185524-","C185525-","C185526-","C185527-","T185528-","A185529-","A185530-","T185531-","T185532-","C185533-","A185534-","T185535-","T185536-","T185537-","T185538-","G185539-","G185540-","G185541-","A185542-","A185543-","G185544-","A185545-","T185546-","G185547-","C185548-","T185549-","A185550-","A185551-","A185552-","A185553-","C185554-","T185555-","A185556-","A185557-","G185558-","A185559-","A185560-","A185561-","C185562-","G185563-","G185564-","A185565-","C185566-","A185567-","T185568-","A185569-","T185570-","A185571-","G185572-","T185573-","G185574-","C185575-","A185576-","A185577-","T185578-","G185579-","A185580-","C185581-","G185582-","A185583-","T185584-","A185585-","A185586-","A185587-","A185588-","G185589-","T185590-","C185591-","C185592-","T185593-","A185594-","C185595-","C185596-","A185597-","T185598-","G185599-","T185600-","A185601-","C185602-","A185603-","G185604-","T185605-","G185606-","A185607-","G185608-","A185609-","A185610-","A185611-","T185612-","A185613-","A185614-","A185615-","A185616-","A185617-","T185618-","A185619-","T185620-","A185621-","G185622-","A185623-","C185624-","T185625-","T185626-","T185627-","G185628-","G185629-","A185630-","T185631-","A185632-","T185633-","A185634-","A185635-","C185636-","T185637-","A185638-","T185639-","G185640-","G185641-","A185642-","G185643-","A185644-","T185645-","A185646-","T185647-","T185648-","A185649-","T185650-","T185651-","T185652-","C185653-","T185654-","A185655-","A185656-","T185657-","A185658-","T185659-","G185660-","G185661-","T185662-","T185663-","T185664-","A185665-","T185666-","C185667-","T185668-","A185669-","C185670-","A185671-","A185672-","T185673-","C185674-","T185675-","A185676-","C185677-","T185678-","A185679-","G185680-","T185681-","C185682-","A185683-","G185684-","G185685-","A185686-","T185687-","T185688-","A185689-","T185690-","G185691-","G185692-","A185693-","G185694-","A185695-","T185696-","G185697-","G185698-","T185699-","A185700-","C185701-","C185702-","A185703-","A185704-","A185705-","T185706-","A185707-","T185708-","A185709-","C185710-","A185711-","T185712-","T185713-","T185714-","A185715-","A185716-","A185717-","T185718-","C185719-","C185720-","G185721-","T185722-","A185723-","A185724-","C185725-","T185726-","A185727-","G185728-","A185729-","T185730-","C185731-","A185732-","G185733-","A185734-","T185735-","C185736-","A185737-","T185738-","G185739-","A185740-","G185741-","T185742-","G185743-","T185744-","G185745-","A185746-","A185747-","T185748-","C185749-","T185750-","A185751-","G185752-","C185753-","T185754-","T185755-","A185756-","G185757-","A185758-","T185759-","C185760-","T185761-","A185762-","A185763-","C185764-","G185765-","T185766-","C185767-","T185768-","A185769-","A185770-","G185771-","G185772-","A185773-","A185774-","G185775-","T185776-","A185777-","A185778-","C185779-","T185780-","G185781-","T185782-","G185783-","A185784-","C185785-","A185786-","T185787-","G185788-","T185789-","C185790-","C185791-","T185792-","G185793-","C185794-","G185795-","T185796-","T185797-","T185798-","A185799-","G185800-","T185801-","A185802-","T185803-","A185804-","C185805-","C185806-","A185807-","A185808-","G185809-","A185810-","A185811-","A185812-","T185813-","A185814-","T185815-","A185816-","T185817-","C185818-","A185819-","A185820-","C185821-","A185822-","T185823-","A185824-","T185825-","G185826-","A185827-","A185828-","G185829-","G185830-","T185831-","C185832-","T185833-","A185834-","T185835-","G185836-","C185837-","T185838-","T185839-","T185840-","A185841-","G185842-","T185843-","G185844-","T185845-","T185846-","A185847-","C185848-","T185849-","A185850-","C185851-","A185852-","T185853-","C185854-","T185855-","A185856-","A185857-","A185858-","G185859-","A185860-","T185861-","C185862-","A185863-","T185864-","T185865-","G185866-","T185867-","G185868-","C185869-","T185870-","A185871-","C185872-","A185873-","G185874-","G185875-","T185876-","A185877-","T185878-","T185879-","G185880-","G185881-","T185882-","T185883-","G185884-","G185885-","T185886-","T185887-","A185888-","A185889-","A185890-","A185891-","T185892-","C185893-","T185894-","A185895-","G185896-","T185897-","G185898-","G185899-","T185900-","T185901-","A185902-","T185903-","G185904-","G185905-","G185906-","A185907-","A185908-","G185909-","G185910-","A185911-","A185912-","G185913-","A185914-","T185915-","G185916-","C185917-","T185918-","G185919-","A185920-","T185921-","A185922-","A185923-","A185924-","C185925-","C185926-","A185927-","C185928-","G185929-","T185930-","G185931-","C185932-","T185933-","T185934-","G185935-","T185936-","T185937-","T185938-","T185939-","C185940-","A185941-","T185942-","C185943-","A185944-","T185945-","T185946-","G185947-","G185948-","A185949-","A185950-","T185951-","T185952-","A185953-","T185954-","T185955-","A185956-","C185957-","A185958-","C185959-","A185960-","C185961-","T185962-","G185963-","T185964-","C185965-","G185966-","T185967-","T185968-","G185969-","G185970-","A185971-","T185972-","T185973-","A185974-","T185975-","T185976-","A185977-","C185978-","T185979-","G185980-","T185981-","T185982-","C185983-","A185984-","T185985-","A185986-","C185987-","G185988-","A185989-","A185990-","G185991-","A185992-","T185993-","A185994-","T185995-","T185996-","T185997-","G185998-","G185999-","A186000-","G186001-","A186002-","A186003-","G186004-","C186005-","A186006-","C186007-","C186008-","T186009-","G186010-","G186011-","C186012-","C186013-","T186014-","G186015-","A186016-","C186017-","T186018-","A186019-","T186020-","G186021-","A186022-","T186023-","C186024-","C186025-","A186026-","T186027-","G186028-","T186029-","A186030-","A186031-","G186032-","T186033-","C186034-","A186035-","T186036-","A186037-","T186038-","A186039-","T186040-","C186041-","C186042-","A186043-","T186044-","A186045-","T186046-","A186047-","G186048-","A186049-","G186050-","T186051-","A186052-","T186053-","A186054-","G186055-","A186056-","G186057-","A186058-","T186059-","A186060-","C186061-","A186062-","T186063-","G186064-","G186065-","A186066-","T186067-","A186068-","G186069-","A186070-","A186071-","T186072-","C186073-","T186074-","A186075-","A186076-","T186077-","G186078-","T186079-","G186080-","T186081-","T186082-","A186083-","C186084-","A186085-","G186086-","C186087-","A186088-","A186089-","C186090-","C186091-","T186092-","C186093-","C186094-","T186095-","T186096-","A186097-","C186098-","A186099-","C186100-","A186101-","T186102-","T186103-","C186104-","G186105-","A186106-","A186107-","T186108-","T186109-","C186110-","A186111-","T186112-","T186113-","C186114-","A186115-","T186116-","G186117-","A186118-","C186119-","A186120-","A186121-","T186122-","T186123-","C186124-","T186125-","A186126-","A186127-","C186128-","G186129-","A186130-","A186131-","T186132-","A186133-","T186134-","G186135-","T186136-","G186137-","G186138-","A186139-","T186140-","A186141-","A186142-","A186143-","G186144-","A186145-","A186146-","A186147-","T186148-","T186149-","A186150-","G186151-","T186152-","A186153-","A186154-","C186155-","A186156-","A186157-","A186158-","T186159-","T186160-","A186161-","A186162-","A186163-","T186164-","G186165-","A186166-","T186167-","C186168-","T186169-","G186170-","T186171-","A186172-","C186173-","A186174-","A186175-","T186176-","G186177-","A186178-","A186179-","T186180-","A186181-","C186182-","A186183-","A186184-","G186185-","A186186-","A186187-","G186188-","A186189-","T186190-","T186191-","A186192-","T186193-","G186194-","G186195-","A186196-","A186197-","T186198-","A186199-","T186200-","A186201-","G186202-","C186203-","G186204-","A186205-","C186206-","G186207-","G186208-","A186209-","T186210-","C186211-","A186212-","T186213-","T186214-","G186215-","C186216-","C186217-","G186218-","G186219-","C186220-","G186221-","T186222-","C186223-","T186224-","A186225-","T186226-","A186227-","A186228-","A186229-","C186230-","A186231-","G186232-","A186233-","T186234-","T186235-","A186236-","G186237-","C186238-","A186239-","A186240-","A186241-","G186242-","G186243-","C186244-","A186245-","T186246-","T186247-","G186248-","A186249-","C186250-","T186251-","T186252-","C186253-","A186254-","G186255-","A186256-","G186257-","G186258-","G186259-","T186260-","A186261-","G186262-","A186263-","G186264-","A186265-","A186266-","A186267-","T186268-","A186269-","G186270-","C186271-","A186272-","A186273-","G186274-","T186275-","G186276-","T186277-","T186278-","A186279-","A186280-","T186281-","A186282-","T186283-","A186284-","G186285-","A186286-","T186287-","G186288-","G186289-","T186290-","A186291-","A186292-","T186293-","C186294-","T186295-","G186296-","T186297-","T186298-","A186299-","G186300-","A186301-","T186302-","A186303-","T186304-","C186305-","G186306-","C186307-","A186308-","T186309-","A186310-","T186311-","C186312-","A186313-","A186314-","G186315-","C186316-","A186317-","G186318-","A186319-","T186320-","A186321-","A186322-","G186323-","G186324-","A186325-","A186326-","A186327-","A186328-","G186329-","A186330-","T186331-","G186332-","G186333-","C186334-","C186335-","G186336-","A186337-","C186338-","A186339-","T186340-","A186341-","C186342-","A186343-","G186344-","A186345-","C186346-","A186347-","A186348-","G186349-","A186350-","A186351-","T186352-","A186353-","A186354-","A186355-","T186356-","G186357-","A186358-","T186359-","A186360-","T186361-","T186362-","A186363-","T186364-","T186365-","A186366-","G186367-","A186368-","G186369-","A186370-","T186371-","T186372-","T186373-","G186374-","T186375-","T186376-","T186377-","A186378-","T186379-","A186380-","C186381-","A186382-","C186383-","A186384-","C186385-","T186386-","C186387-","T186388-","A186389-","T186390-","C186391-","A186392-","G186393-","A186394-","C186395-","A186396-","A186397-","A186398-","G186399-","A186400-","T186401-","A186402-","T186403-","A186404-","A186405-","A186406-","A186407-","G186408-","A186409-","C186410-","A186411-","T186412-","T186413-","A186414-","T186415-","A186416-","G186417-","A186418-","A186419-","T186420-","C186421-","C186422-","G186423-","A186424-","A186425-","G186426-","A186427-","A186428-","G186429-","G186430-","T186431-","A186432-","A186433-","G186434-","A186435-","G186436-","A186437-","T186438-","G186439-","T186440-","T186441-","G186442-","T186443-","A186444-","T186445-","A186446-","A186447-","T186448-","A186449-","G186450-","A186451-","T186452-","G186453-","T186454-","T186455-","A186456-","A186457-","G186458-","A186459-","A186460-","C186461-","A186462-","A186463-","T186464-","C186465-","T186466-","T186467-","G186468-","T186469-","T186470-","A186471-","A186472-","A186473-","A186474-","A186475-","G186476-","T186477-","A186478-","C186479-","T186480-","A186481-","T186482-","T186483-","C186484-","T186485-","A186486-","T186487-","T186488-","G186489-","A186490-","T186491-","A186492-","A186493-","T186494-","T186495-","A186496-","T186497-","C186498-","T186499-","A186500-","T186501-","G186502-","T186503-","G186504-","A186505-","T186506-","A186507-","C186508-","T186509-","T186510-","T186511-","A186512-","G186513-","A186514-","T186515-","G186516-","A186517-","T186518-","T186519-","A186520-","T186521-","A186522-","T186523-","A186524-","T186525-","A186526-","C186527-","A186528-","C186529-","C186530-","T186531-","C186532-","T186533-","G186534-","T186535-","A186536-","G186537-","A186538-","A186539-","T186540-","A186541-","T186542-","A186543-","A186544-","C186545-","A186546-","A186547-","A186548-","T186549-","C186550-","C186551-","T186552-","A186553-","T186554-","G186555-","T186556-","G186557-","T186558-","T186559-","A186560-","G186561-","T186562-","A186563-","A186564-","A186565-","C186566-","G186567-","A186568-","T186569-","A186570-","C186571-","T186572-","T186573-","A186574-","T186575-","A186576-","T186577-","G186578-","A186579-","G186580-","C186581-","T186582-","A186583-","T186584-","G186585-","A186586-","C186587-","T186588-","A186589-","T186590-","C186591-","T186592-","T186593-","G186594-","A186595-","A186596-","T186597-","C186598-","A186599-","T186600-","C186601-","A186602-","G186603-","G186604-","T186605-","G186606-","T186607-","A186608-","G186609-","T186610-","T186611-","G186612-","T186613-","T186614-","C186615-","T186616-","A186617-","T186618-","C186619-","A186620-","T186621-","G186622-","T186623-","T186624-","A186625-","T186626-","G186627-","A186628-","A186629-","A186630-","T186631-","G186632-","A186633-","C186634-","T186635-","A186636-","T186637-","A186638-","A186639-","T186640-","C186641-","T186642-","C186643-","C186644-","T186645-","T186646-","G186647-","G186648-","A186649-","T186650-","A186651-","C186652-","A186653-","A186654-","A186655-","A186656-","G186657-","A186658-","C186659-","G186660-","C186661-","C186662-","A186663-","A186664-","A186665-","G186666-","A186667-","T186668-","G186669-","C186670-","T186671-","A186672-","T186673-","A186674-","G186675-","A186676-","A186677-","G186678-","A186679-","T186680-","G186681-","T186682-","G186683-","A186684-","T186685-","A186686-","G186687-","T186688-","A186689-","G186690-","C186691-","A186692-","A186693-","G186694-","T186695-","G186696-","C186697-","G186698-","G186699-","T186700-","A186701-","G186702-","C186703-","C186704-","G186705-","A186706-","A186707-","G186708-","C186709-","A186710-","T186711-","T186712-","G186713-","A186714-","A186715-","T186716-","G186717-","A186718-","C186719-","A186720-","T186721-","G186722-","T186723-","T186724-","T186725-","A186726-","A186727-","G186728-","G186729-","A186730-","A186731-","T186732-","T186733-","T186734-","G186735-","A186736-","T186737-","A186738-","A186739-","A186740-","A186741-","A186742-","C186743-","G186744-","T186745-","A186746-","A186747-","G186748-","T186749-","G186750-","C186751-","T186752-","A186753-","T186754-","T186755-","A186756-","T186757-","A186758-","A186759-","T186760-","A186761-","A186762-","A186763-","A186764-","G186765-","A186766-","A186767-","G186768-","A186769-","A186770-","G186771-","A186772-","T186773-","A186774-","A186775-","T186776-","T186777-","A186778-","T186779-","C186780-","T186781-","A186782-","A186783-","A186784-","C186785-","A186786-","G186787-","T186788-","T186789-","C186790-","G186791-","C186792-","C186793-","C186794-","G186795-","A186796-","T186797-","A186798-","T186799-","C186800-","T186801-","A186802-","C186803-","C186804-","A186805-","T186806-","A186807-","T186808-","A186809-","A186810-","T186811-","A186812-","T186813-","A186814-","T186815-","A186816-","T186817-","C186818-","A186819-","T186820-","A186821-","G186822-","G186823-","T186824-","G186825-","G186826-","C186827-","A186828-","C186829-","T186830-","A186831-","T186832-","T186833-","C186834-","T186835-","G186836-","C186837-","T186838-","A186839-","C186840-","T186841-","G186842-","T186843-","T186844-","A186845-","G186846-","T186847-","C186848-","A186849-","T186850-","T186851-","A186852-","T186853-","T186854-","T186855-","T186856-","A186857-","A186858-","T186859-","A186860-","T186861-","T186862-","G186863-","G186864-","C186865-","A186866-","A186867-","T186868-","T186869-","T186870-","A186871-","T186872-","A186873-","T186874-","A186875-","G186876-","C186877-","G186878-","C186879-","G186880-","C186881-","A186882-","A186883-","T186884-","A186885-","A186886-","A186887-","T186888-","A186889-","C186890-","A186891-","G186892-","A186893-","A186894-","C186895-","C186896-","A186897-","G186898-","G186899-","A186900-","A186901-","A186902-","T186903-","A186904-","T186905-","G186906-","A186907-","A186908-","A186909-","T186910-","A186911-","A186912-","T186913-","G186914-","A186915-","A186916-","A186917-","T186918-","A186919-","T186920-","G186921-","A186922-","C186923-","A186924-","A186925-","T186926-","A186927-","T186928-","G186929-","A186930-","G186931-","C186932-","A186933-","T186934-","T186935-","A186936-","A186937-","A186938-","T186939-","C186940-","T186941-","G186942-","A186943-","G186944-","C186945-","A186946-","T186947-","C186948-","A186949-","T186950-","G186951-","A186952-","T186953-","A186954-","G186955-","T186956-","C186957-","T186958-","T186959-","G186960-","A186961-","A186962-","A186963-","C186964-","A186965-","G186966-","T186967-","G186968-","T186969-","C186970-","T186971-","A186972-","T186973-","G186974-","G186975-","A186976-","A186977-","A186978-","T186979-","T186980-","A186981-","T186982-","T186983-","G186984-","A186985-","T186986-","A186987-","A186988-","T186989-","C186990-","G186991-","G186992-","T186993-","A186994-","C186995-","T186996-","A186997-","A186998-","T186999-","A187000-","A187001-","A187002-","A187003-","T187004-","A187005-","G187006-","T187007-","T187008-","T187009-","A187010-","A187011-","C187012-","T187013-","C187014-","T187015-","T187016-","T187017-","T187018-","A187019-","G187020-","A187021-","A187022-","C187023-","C187024-","A187025-","G187026-","T187027-","T187028-","T187029-","G187030-","G187031-","T187032-","A187033-","C187034-","T187035-","G187036-","T187037-","A187038-","A187039-","T187040-","T187041-","T187042-","C187043-","A187044-","G187045-","T187046-","T187047-","C187048-","A187049-","T187050-","T187051-","A187052-","C187053-","T187054-","C187055-","G187056-","T187057-","T187058-","G187059-","A187060-","G187061-","A187062-","A187063-","T187064-","A187065-","T187066-","T187067-","G187068-","A187069-","T187070-","G187071-","A187072-","T187073-","T187074-","T187075-","T187076-","T187077-","T187078-","T187079-","T187080-","A187081-","A187082-","A187083-","T187084-","G187085-","A187086-","G187087-","T187088-","A187089-","T187090-","C187091-","G187092-","G187093-","T187094-","A187095-","G187096-","T187097-","T187098-","A187099-","C187100-","A187101-","T187102-","A187103-","T187104-","T187105-","A187106-","C187107-","C187108-","A187109-","T187110-","A187111-","T187112-","C187113-","A187114-","T187115-","C187116-","C187117-","A187118-","T187119-","T187120-","A187121-","T187122-","A187123-","T187124-","A187125-","A187126-","T187127-","C187128-","G187129-","A187130-","T187131-","G187132-","A187133-","T187134-","G187135-","C187136-","A187137-","T187138-","G187139-","T187140-","A187141-","T187142-","T187143-","A187144-","G187145-","A187146-","A187147-","T187148-","A187149-","C187150-","T187151-","T187152-","T187153-","C187154-","C187155-","G187156-","A187157-","A187158-","T187159-","A187160-","A187161-","G187162-","T187163-","C187164-","T187165-","T187166-","C187167-","T187168-","A187169-","A187170-","A187171-","T187172-","A187173-","T187174-","T187175-","G187176-","T187177-","A187178-","T187179-","T187180-","A187181-","A187182-","T187183-","T187184-","A187185-","T187186-","G187187-","A187188-","A187189-","A187190-","A187191-","A187192-","C187193-","T187194-","A187195-","T187196-","G187197-","C187198-","T187199-","A187200-","T187201-","G187202-","T187203-","G187204-","A187205-","G187206-","T187207-","A187208-","T187209-","G187210-","A187211-","T187212-","T187213-","C187214-","A187215-","A187216-","A187217-","G187218-","A187219-","T187220-","G187221-","T187222-","T187223-","T187224-","A187225-","A187226-","T187227-","G187228-","A187229-","T187230-","A187231-","C187232-","G187233-","A187234-","T187235-","A187236-","C187237-","T187238-","A187239-","G187240-","A187241-","T187242-","T187243-","T187244-","T187245-","A187246-","T187247-","C187248-","T187249-","C187250-","T187251-","A187252-","G187253-","C187254-","G187255-","A187256-","G187257-","A187258-","T187259-","T187260-","G187261-","T187262-","T187263-","T187264-","A187265-","G187266-","A187267-","A187268-","T187269-","C187270-","A187271-","T187272-","T187273-","T187274-","A187275-","T187276-","C187277-","A187278-","T187279-","A187280-","A187281-","C187282-","T187283-","A187284-","T187285-","G187286-","T187287-","T187288-","T187289-","A187290-","A187291-","T187292-","A187293-","A187294-","A187295-","T187296-","T187297-","C187298-","A187299-","T187300-","C187301-","A187302-","A187303-","C187304-","G187305-","A187306-","A187307-","T187308-","A187309-","T187310-","C187311-","G187312-","A187313-","T187314-","A187315-","A187316-","A187317-","G187318-","A187319-","C187320-","C187321-","T187322-","C187323-","T187324-","T187325-","G187326-","T187327-","A187328-","A187329-","T187330-","T187331-","C187332-","G187333-","A187334-","G187335-","T187336-","A187337-","T187338-","A187339-","G187340-","G187341-","A187342-","A187343-","G187344-","T187345-","A187346-","G187347-","T187348-","A187349-","T187350-","T187351-","A187352-","C187353-","C187354-","A187355-","T187356-","A187357-","T187358-","C187359-","A187360-","A187361-","C187362-","T187363-","T187364-","C187365-","C187366-","G187367-","A187368-","G187369-","T187370-","T187371-","A187372-","A187373-","C187374-","A187375-","A187376-","T187377-","T187378-","A187379-","C187380-","T187381-","C187382-","T187383-","A187384-","A187385-","A187386-","A187387-","C187388-","A187389-","T187390-","G187391-","A187392-","G187393-","G187394-","A187395-","T187396-","T187397-","G187398-","T187399-","A187400-","C187401-","T187402-","C187403-","C187404-","T187405-","G187406-","T187407-","C187408-","T187409-","T187410-","T187411-","A187412-","T187413-","T187414-","G187415-","G187416-","A187417-","G187418-","A187419-","T187420-","C187421-","A187422-","C187423-","T187424-","A187425-","T187426-","T187427-","T187428-","A187429-","G187430-","T187431-","C187432-","G187433-","T187434-","T187435-","G187436-","A187437-","T187438-","A187439-","A187440-","A187441-","C187442-","T187443-","A187444-","G187445-","T187446-","A187447-","A187448-","C187449-","C187450-","T187451-","C187452-","A187453-","G187454-","G187455-","T187456-","T187457-","T187458-","C187459-","T187460-","T187461-","T187462-","A187463-","C187464-","A187465-","A187466-","A187467-","C187468-","G187469-","A187470-","T187471-","A187472-","A187473-","A187474-","G187475-","T187476-","A187477-","C187478-","A187479-","A187480-","C187481-","A187482-","T187483-","C187484-","A187485-","A187486-","G187487-","A187488-","C187489-","C187490-","T187491-","C187492-","A187493-","C187494-","A187495-","A187496-","C187497-","A187498-","C187499-","A187500-","G187501-","T187502-","G187503-","C187504-","A187505-","A187506-","G187507-","A187508-","T187509-","T187510-","A187511-","A187512-","T187513-","C187514-","T187515-","A187516-","G187517-","A187518-","A187519-","A187520-","T187521-","C187522-","A187523-","A187524-","A187525-","T187526-","G187527-","T187528-","A187529-","A187530-","T187531-","T187532-","C187533-","T187534-","G187535-","G187536-","A187537-","G187538-","G187539-","A187540-","G187541-","A187542-","A187543-","T187544-","C187545-","T187546-","A187547-","G187548-","A187549-","C187550-","A187551-","A187552-","C187553-","T187554-","A187555-","A187556-","C187557-","A187558-","C187559-","C187560-","C187561-","A187562-","C187563-","G187564-","G187565-","C187566-","G187567-","A187568-","A187569-","G187570-","T187571-","A187572-","T187573-","A187574-","C187575-","T187576-","T187577-","T187578-","A187579-","T187580-","G187581-","C187582-","C187583-","T187584-","C187585-","A187586-","T187587-","T187588-","C187589-","A187590-","G187591-","A187592-","A187593-","A187594-","C187595-","G187596-","G187597-","T187598-","A187599-","A187600-","C187601-","T187602-","G187603-","T187604-","A187605-","G187606-","T187607-","A187608-","G187609-","G187610-","A187611-","G187612-","A187613-","C187614-","T187615-","G187616-","T187617-","C187618-","T187619-","C187620-","T187621-","C187622-","T187623-","A187624-","A187625-","T187626-","C187627-","T187628-","C187629-","G187630-","A187631-","T187632-","G187633-","T187634-","A187635-","T187636-","A187637-","T187638-","A187639-","T187640-","A187641-","A187642-","T187643-","A187644-","T187645-","A187646-","T187647-","A187648-","C187649-","C187650-","A187651-","A187652-","T187653-","A187654-","C187655-","G187656-","G187657-","A187658-","C187659-","G187660-","C187661-","G187662-","A187663-","T187664-","A187665-","T187666-","A187667-","T187668-","T187669-","C187670-","C187671-","G187672-","A187673-","C187674-","A187675-","T187676-","G187677-","A187678-","A187679-","T187680-","G187681-","G187682-","C187683-","G187684-","T187685-","C187686-","G187687-","C187688-","T187689-","T187690-","A187691-","T187692-","C187693-","A187694-","T187695-","A187696-","T187697-","G187698-","T187699-","T187700-","A187701-","T187702-","A187703-","T187704-","C187705-","C187706-","T187707-","A187708-","A187709-","A187710-","T187711-","G187712-","T187713-","T187714-","G187715-","A187716-","T187717-","C187718-","A187719-","T187720-","A187721-","T187722-","T187723-","C187724-","C187725-","A187726-","C187727-","A187728-","A187729-","A187730-","T187731-","G187732-","A187733-","T187734-","T187735-","G187736-","T187737-","G187738-","A187739-","A187740-","C187741-","G187742-","A187743-","G187744-","A187745-","T187746-","T187747-","A187748-","A187749-","A187750-","T187751-","C187752-","A187753-","T187754-","C187755-","T187756-","A187757-","A187758-","C187759-","A187760-","A187761-","A187762-","T187763-","A187764-","A187765-","T187766-","T187767-","A187768-","G187769-","T187770-","T187771-","T187772-","T187773-","T187774-","T187775-","A187776-","T187777-","G187778-","A187779-","C187780-","A187781-","T187782-","T187783-","A187784-","A187785-","C187786-","A187787-","T187788-","A187789-","T187790-","A187791-","A187792-","T187793-","A187794-","A187795-","A187796-","T187797-","A187798-","A187799-","A187800-","T187801-","T187802-","A187803-","A187804-","T187805-","C187806-","A187807-","T187808-","T187809-","A187810-","T187811-","T187812-","G187813-","A187814-","C187815-","T187816-","T187817-","A187818-","A187819-","C187820-","G187821-","A187822-","T187823-","G187824-","A187825-","C187826-","G187827-","A187828-","A187829-","A187830-","G187831-","T187832-","T187833-","A187834-","T187835-","C187836-","A187837-","T187838-","T187839-","A187840-","T187841-","C187842-","T187843-","T187844-","A187845-","G187846-","G187847-","A187848-","T187849-","T187850-","C187851-","T187852-","T187853-","G187854-","A187855-","T187856-","T187857-","A187858-","T187859-","T187860-","A187861-","A187862-","T187863-","A187864-","C187865-","A187866-","A187867-","A187868-","T187869-","T187870-","C187871-","G187872-","T187873-","T187874-","G187875-","T187876-","G187877-","T187878-","C187879-","T187880-","A187881-","T187882-","G187883-","A187884-","A187885-","A187886-","T187887-","G187888-","T187889-","G187890-","A187891-","A187892-","C187893-","A187894-","A187895-","G187896-","G187897-","T187898-","G187899-","T187900-","C187901-","T187902-","C187903-","A187904-","T187905-","A187906-","T187907-","T187908-","A187909-","T187910-","A187911-","A187912-","T187913-","G187914-","C187915-","A187916-","C187917-","A187918-","A187919-","G187920-","A187921-","A187922-","T187923-","T187924-","A187925-","A187926-","A187927-","G187928-","T187929-","G187930-","T187931-","T187932-","G187933-","T187934-","A187935-","A187936-","A187937-","C187938-","T187939-","A187940-","T187941-","C187942-","T187943-","A187944-","G187945-","C187946-","C187947-","A187948-","G187949-","G187950-","A187951-","A187952-","C187953-","A187954-","T187955-","A187956-","T187957-","T187958-","C187959-","A187960-","G187961-","A187962-","T187963-","T187964-","A187965-","T187966-","C187967-","G187968-","A187969-","T187970-","G187971-","T187972-","G187973-","A187974-","T187975-","A187976-","A187977-","A187978-","T187979-","A187980-","C187981-","A187982-","G187983-","C187984-","G187985-","A187986-","T187987-","A187988-","C187989-","C187990-","A187991-","T187992-","C187993-","T187994-","G187995-","T187996-","G187997-","G187998-","A187999-","C188000-","A188001-","T188002-","T188003-","G188004-","T188005-","C188006-","C188007-","A188008-","A188009-","G188010-","T188011-","G188012-","A188013-","C188014-","A188015-","C188016-","A188017-","T188018-","T188019-","C188020-","A188021-","C188022-","G188023-","T188024-","C188025-","A188026-","A188027-","T188028-","A188029-","T188030-","A188031-","T188032-","A188033-","A188034-","T188035-","C188036-","G188037-","T188038-","T188039-","C188040-","T188041-","C188042-","C188043-","T188044-","C188045-","G188046-","G188047-","T188048-","G188049-","T188050-","C188051-","A188052-","T188053-","A188054-","G188055-","T188056-","T188057-","G188058-","T188059-","A188060-","G188061-","A188062-","G188063-","G188064-","T188065-","C188066-","A188067-","C188068-","A188069-","C188070-","C188071-","T188072-","T188073-","G188074-","T188075-","A188076-","C188077-","A188078-","C188079-","C188080-","T188081-","A188082-","C188083-","C188084-","A188085-","C188086-","A188087-","A188088-","A188089-","T188090-","A188091-","G188092-","A188093-","A188094-","T188095-","A188096-","T188097-","G188098-","T188099-","C188100-","A188101-","T188102-","T188103-","G188104-","T188105-","G188106-","A188107-","C188108-","T188109-","C188110-","G188111-","A188112-","A188113-","T188114-","A188115-","G188116-","T188117-","T188118-","A188119-","T188120-","C188121-","G188122-","T188123-","C188124-","T188125-","C188126-","C188127-","T188128-","T188129-","A188130-","A188131-","A188132-","G188133-","C188134-","T188135-","T188136-","C188137-","T188138-","G188139-","A188140-","T188141-","G188142-","G188143-","T188144-","A188145-","A188146-","C188147-","T188148-","G188149-","T188150-","G188151-","T188152-","T188153-","A188154-","C188155-","A188156-","T188157-","G188158-","T188159-","G188160-","C188161-","T188162-","C188163-","C188164-","T188165-","A188166-","A188167-","A188168-","A188169-","C188170-","A188171-","A188172-","A188173-","A188174-","T188175-","A188176-","T188177-","G188178-","G188179-","T188180-","C188181-","G188182-","T188183-","G188184-","T188185-","G188186-","T188187-","A188188-","C188189-","G188190-","G188191-","A188192-","A188193-","A188194-","G188195-","A188196-","A188197-","A188198-","G188199-","G188200-","A188201-","G188202-","A188203-","A188204-","A188205-","A188206-","T188207-","G188208-","A188209-","T188210-","A188211-","T188212-","G188213-","G188214-","A188215-","A188216-","T188217-","A188218-","C188219-","C188220-","A188221-","T188222-","T188223-","T188224-","G188225-","T188226-","A188227-","A188228-","G188229-","A188230-","A188231-","A188232-","T188233-","G188234-","T188235-","C188236-","G188237-","G188238-","A188239-","A188240-","G188241-","G188242-","G188243-","T188244-","A188245-","C188246-","T188247-","T188248-","A188249-","T188250-","T188251-","C188252-","A188253-","G188254-","A188255-","T188256-","A188257-","T188258-","T188259-","G188260-","T188261-","A188262-","T188263-","C188264-","T188265-","G188266-","A188267-","C188268-","T188269-","C188270-","T188271-","G188272-","A188273-","T188274-","C188275-","A188276-","A188277-","T188278-","G188279-","T188280-","A188281-","A188282-","A188283-","C188284-","C188285-","T188286-","A188287-","T188288-","G188289-","A188290-","C188291-","A188292-","A188293-","G188294-","A188295-","T188296-","A188297-","A188298-","G188299-","A188300-","C188301-","T188302-","T188303-","A188304-","C188305-","T188306-","C188307-","G188308-","C188309-","A188310-","T188311-","C188312-","T188313-","A188314-","C188315-","T188316-","G188317-","G188318-","A188319-","T188320-","A188321-","G188322-","A188323-","C188324-","A188325-","T188326-","A188327-","A188328-","A188329-","T188330-","A188331-","T188332-","C188333-","C188334-","T188335-","C188336-","C188337-","T188338-","C188339-","G188340-","T188341-","A188342-","A188343-","T188344-","A188345-","A188346-","T188347-","G188348-","A188349-","A188350-","A188351-","T188352-","A188353-","T188354-","A188355-","A188356-","T188357-","A188358-","T188359-","A188360-","C188361-","A188362-","C188363-","T188364-","A188365-","A188366-","T188367-","T188368-","A188369-","T188370-","T188371-","A188372-","A188373-","T188374-","A188375-","T188376-","C188377-","A188378-","A188379-","T188380-","C188381-","G188382-","A188383-","G188384-","T188385-","A188386-","T188387-","T188388-","A188389-","A188390-","C188391-","A188392-","T188393-","A188394-","T188395-","A188396-","A188397-","G188398-","T188399-","T188400-","A188401-","T188402-","T188403-","T188404-","T188405-","T188406-","A188407-","A188408-","A188409-","C188410-","C188411-","C188412-","C188413-","T188414-","T188415-","T188416-","T188417-","G188418-","G188419-","G188420-","T188421-","T188422-","C188423-","C188424-","G188425-","T188426-","C188427-","C188428-","T188429-","A188430-","A188431-","A188432-","C188433-","G188434-","G188435-","C188436-","G188437-","T188438-","T188439-","T188440-","C188441-","G188442-","G188443-","T188444-","C188445-","T188446-","G188447-","T188448-","G188449-","T188450-","C188451-","G188452-","C188453-","C188454-","A188455-","C188456-","C188457-","A188458-","T188459-","G188460-","G188461-","T188462-","C188463-","A188464-","C188465-","A188466-","C188467-","C188468-","G188469-","A188470-","G188471-","C188472-","C188473-","T188474-","C188475-","T188476-","G188477-","C188478-","G188479-","T188480-","G188481-","C188482-","T188483-","C188484-","C188485-","T188486-","C188487-","C188488-","A188489-","T188490-","C188491-","G188492-","A188493-","G188494-","G188495-","A188496-","C188497-","G188498-","A188499-","C188500-","T188501-","T188502-","C188503-","A188504-","A188505-","C188506-","T188507-","A188508-","T188509-","G188510-","A188511-","C188512-","A188513-","G188514-","C188515-","T188516-","C188517-","G188518-","G188519-","T188520-","G188521-","G188522-","C188523-","G188524-","T188525-","C188526-","T188527-","G188528-","C188529-","C188530-","A188531-","G188532-","C188533-","G188534-","T188535-","G188536-","T188537-","A188538-","C188539-","A188540-","T188541-","A188542-","C188543-","G188544-","A188545-","A188546-","T188547-","G188548-","G188549-","C188550-","A188551-","T188552-","T188553-","T188554-","C188555-","T188556-","A188557-","A188558-","G188559-","A188560-","A188561-","A188562-","A188563-","G188564-","T188565-","C188566-","T188567-","A188568-","C188569-","G188570-","G188571-","T188572-","A188573-","T188574-","C188575-","C188576-","T188577-","T188578-","T188579-","C188580-","T188581-","A188582-","C188583-","A188584-","A188585-","T188586-","T188587-","T188588-","C188589-","C188590-","T188591-","T188592-","T188593-","A188594-","A188595-","C188596-","A188597-","A188598-","C188599-","G188600-","G188601-","C188602-","A188603-","A188604-","C188605-","A188606-","G188607-","C188608-","T188609-","G188610-","C188611-","A188612-","G188613-","T188614-","A188615-","T188616-","T188617-","T188618-","T188619-","T188620-","A188621-","T188622-","A188623-","C188624-","T188625-","T188626-","T188627-","G188628-","A188629-","A188630-","T188631-","G188632-","C188633-","A188634-","T188635-","C188636-","G188637-","G188638-","A188639-","C188640-","A188641-","T188642-","T188643-","T188644-","A188645-","T188646-","A188647-","C188648-","A188649-","A188650-","G188651-","G188652-","G188653-","A188654-","G188655-","T188656-","C188657-","C188658-","T188659-","G188660-","T188661-","T188662-","C188663-","T188664-","A188665-","A188666-","T188667-","A188668-","T188669-","T188670-","G188671-","G188672-","C188673-","A188674-","T188675-","C188676-","A188677-","A188678-","T188679-","G188680-","T188681-","T188682-","C188683-","G188684-","G188685-","A188686-","T188687-","C188688-","T188689-","A188690-","T188691-","A188692-","G188693-","G188694-","C188695-","T188696-","T188697-","G188698-","A188699-","T188700-","T188701-","T188702-","T188703-","C188704-","G188705-","C188706-","A188707-","T188708-","T188709-","G188710-","A188711-","C188712-","T188713-","T188714-","T188715-","A188716-","C188717-","A188718-","C188719-","A188720-","G188721-","A188722-","C188723-","A188724-","T188725-","G188726-","A188727-","A188728-","C188729-","A188730-","T188731-","C188732-","C188733-","C188734-","C188735-","T188736-","G188737-","A188738-","A188739-","T188740-","C188741-","T188742-","G188743-","T188744-","A188745-","C188746-","A188747-","T188748-","A188749-","C188750-","T188751-","T188752-","T188753-","G188754-","T188755-","G188756-","G188757-","A188758-","T188759-","T188760-","T188761-","A188762-","C188763-","A188764-","C188765-","T188766-","G188767-","T188768-","T188769-","A188770-","G188771-","A188772-","A188773-","T188774-","C188775-","T188776-","C188777-","T188778-","A188779-","A188780-","C188781-","G188782-","C188783-","T188784-","G188785-","G188786-","C188787-","C188788-","T188789-","C188790-","T188791-","G188792-","T188793-","T188794-","G188795-","T188796-","T188797-","A188798-","C188799-","T188800-","T188801-","T188802-","C188803-","T188804-","A188805-","T188806-","G188807-","A188808-","T188809-","G188810-","C188811-","A188812-","C188813-","G188814-","T188815-","A188816-","T188817-","C188818-","G188819-","T188820-","T188821-","A188822-","T188823-","G188824-","C188825-","A188826-","A188827-","G188828-","C188829-","T188830-","T188831-","T188832-","C188833-","A188834-","T188835-","G188836-","T188837-","T188838-","G188839-","A188840-","C188841-","T188842-","A188843-","C188844-","T188845-","G188846-","C188847-","A188848-","G188849-","T188850-","G188851-","T188852-","T188853-","T188854-","C188855-","T188856-","T188857-","G188858-","C188859-","T188860-","C188861-","T188862-","G188863-","A188864-","C188865-","T188866-","A188867-","C188868-","A188869-","T188870-","A188871-","T188872-","A188873-","C188874-","T188875-","C188876-","T188877-","A188878-","C188879-","A188880-","A188881-","T188882-","C188883-","A188884-","A188885-","A188886-","G188887-","A188888-","G188889-","A188890-","G188891-","A188892-","T188893-","T188894-","T188895-","C188896-","A188897-","G188898-","T188899-","A188900-","A188901-","A188902-","C188903-","T188904-","T188905-","G188906-","T188907-","A188908-","A188909-","C188910-","A188911-","G188912-","G188913-","A188914-","T188915-","T188916-","G188917-","T188918-","T188919-","T188920-","G188921-","C188922-","T188923-","G188924-","C188925-","T188926-","T188927-","T188928-","C188929-","T188930-","G188931-","G188932-","A188933-","T188934-","-196616A"],"OPG023":["D392N"],"OPG057":["E353K"]},"labels":{"aa":"OPG023: D392N; OPG057: E353K"}}},{"name":"OP612688","node_attrs":{"div":28,"accession":"OP612688","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/104/19"},"date":{"value":"2019-11-02"},"strain_display":{"value":"Nigeria/OP612688/2019-11-02"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","G1126A","G2039A","G2152A","C6948T","C47224T","T76087-","C77726T","C143845T","G152431A","C166786T","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","G184037T","C184535T","C195058T","C195171T","C196084T"],"OPG002":["S238L"],"OPG002_dup":["S238L"],"OPG066":["E69K"],"OPG099":["S21F"],"OPG192":["S19L"]},"labels":{"aa":"OPG002: S238L; OPG002_dup: S238L; OPG066: E69K; OPG099: S21F; OPG192: S19L"}}},{"name":"OP612674","node_attrs":{"div":23,"accession":"OP612674","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/003/19"},"date":{"value":"2019-01-12"},"strain_display":{"value":"Nigeria/OP612674/2019-01-12"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C11555T","G28645A","G75967A","T76087-","G94840A","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","C188503T","A196612-","A196613-","A196614-","A196615-"],"OPG023":["R449Q"],"OPG115":["E61K"]},"labels":{"aa":"OPG023: R449Q; OPG115: E61K"}}},{"name":"NODE_0000028","node_attrs":{"div":19,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","G151929A","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","-196616A","-196617A"],"OPG178":["E141K"]},"labels":{"aa":"OPG178: E141K"}},"children":[{"name":"OL504742","node_attrs":{"div":26,"accession":"OL504742","author":{"author":"Atkinson,B.,Pottage,T.,Ngabo,D.,Crook,A.,Pitman,J.,Summers,S.,Pullan,S.,Lewandowski,K.,Furneaux,J.,Davies,K.,Brooks,T.","value":"Atkinson,B.,Pottage,T.,Ngabo,D.,Crook,A.,Pitman,J.,Summers,S.,Pullan,S.,Lewandowski,K.,Furneaux,J.,Davies,K.,Brooks,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research"},"lineage":{"value":"A.1"},"strain":{"value":"2095"},"date":{"value":"2019-12-XX"},"strain_display":{"value":"United Kingdom/OL504742/2019-12-XX"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C13065T","C29887T","G61329A","C72206T","G103431A","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","C165369T","-173290A","-173291T","-173292A","-173293T","-173294A","-173295T","-173296A","-173300A","-173301T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G188949A","T192184C"],"OPG024":["G55E"],"OPG092":["E248K"],"OPG123":["S547L"],"OPG190":["S83F"]},"labels":{"aa":"OPG024: G55E; OPG092: E248K; OPG123: S547L; OPG190: S83F"}}},{"name":"OP612683","node_attrs":{"div":21,"accession":"OP612683","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/042/19"},"date":{"value":"2019-04-18"},"strain_display":{"value":"Nigeria/OP612683/2019-04-18"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-608T","T76087-","G81523A","C141757T"],"OPG105":["S133N"]},"labels":{"aa":"OPG105: S133N"}}},{"name":"NODE_0000029","node_attrs":{"div":20,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["C39767T"]}},"children":[{"name":"MT903342","node_attrs":{"div":22,"accession":"MT903342","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Singapore"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-Singapore"},"date":{"value":"2019-05-XX"},"strain_display":{"value":"Singapore/MT903342/2019-05-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-608T","C43927T","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","C170573T","-173290A","-173291T","-173292A","-173293T","-173294A","-173295T","-173296A","-173297T","-173298A","-173299T","-173300A","-173301T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A196617-"],"OPG064":["E658K"],"OPG198":["S179L"]},"labels":{"aa":"OPG064: E658K; OPG198: S179L"}}},{"name":"OP612685","node_attrs":{"div":20,"accession":"OP612685","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/052/19"},"date":{"value":"2019-05-29"},"strain_display":{"value":"Nigeria/OP612685/2019-05-29"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-"]}}}]}]},{"name":"NODE_0000030","node_attrs":{"div":20,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["G25661A","C39119T","-173314A","-173315T","-173316A","-173317T"]}},"children":[{"name":"OP612679","node_attrs":{"div":28,"accession":"OP612679","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/018/19"},"date":{"value":"2019-03-14"},"strain_display":{"value":"Nigeria/OP612679/2019-03-14"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C8500T","G79538A","G81354A","G84416A","C88736T","G100642A","C138791T","C161616T","-196616A","-196617A"],"OPG102":["D152N"],"OPG105":["E77K"],"OPG109":["E238K"],"OPG119":["R86K"],"OPG156":["D207N"]},"labels":{"aa":"OPG102: D152N; OPG105: E77K; OPG109: E238K; OPG119: R86K; OPG156: D207N"}}},{"name":"NODE_0000031","node_attrs":{"div":21,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["T607-","G162243A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","A196615-"]}},"children":[{"name":"MT903345","node_attrs":{"div":21,"accession":"MT903345","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-UK_P3"},"date":{"value":"2018-09-XX"},"strain_display":{"value":"United Kingdom/MT903345/2018-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"MT903344","node_attrs":{"div":21,"accession":"MT903344","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-UK_P2"},"date":{"value":"2018-09-XX"},"strain_display":{"value":"United Kingdom/MT903344/2018-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"]}}},{"name":"NODE_0000032","node_attrs":{"div":24,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["G1262A","C3818T","G124130A","C128698T","T133102-","T133177-","C133178-","T133179-","T133180-","T133181-","C133182-","T133183-","C133184-","A133185-","A133186-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179177T","-179178A","G193392A","C195948T"],"OPG001":["S105L"],"OPG001_dup":["S105L"],"OPG003":["D264N"],"OPG003_dup":["D264N"],"OPG145":["E62K"],"OPG150":["S307L"]},"labels":{"aa":"OPG001: S105L; OPG001_dup: S105L; OPG003: D264N; OPG003_dup: D264N; OPG145: E62K; OPG150: S307L"}},"children":[{"name":"OP612687","node_attrs":{"div":29,"accession":"OP612687","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/058/19"},"date":{"value":"2019-07-11"},"strain_display":{"value":"Nigeria/OP612687/2019-07-11"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","C756T","G2039A","G168365A","A173288-","T173289-","-179172C","-179173A","-179174T","-179175T","-179176A","C188605A","A188606C","G188607A","T193455A","C195171T","G196454-","A196614-"],"OPG002":["S238L"],"OPG002_dup":["S238L"],"OPG003_dup":["L285I"],"OPG195":["E46K"]},"labels":{"aa":"OPG002: S238L; OPG002_dup: S238L; OPG003_dup: L285I; OPG195: E46K"}}},{"name":"NODE_0000033","node_attrs":{"div":25,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["G81275A"]}},"children":[{"name":"OP612686","node_attrs":{"div":26,"accession":"OP612686","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/053/19"},"date":{"value":"2019-06-26"},"strain_display":{"value":"Nigeria/OP612686/2019-06-26"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","T76087-","G88640A","-179172C","-179173A","-179174T","-179175T","-179176A","-196615A","-196616A","-196617A"],"OPG109":["R270C"]},"labels":{"aa":"OPG109: R270C"}}},{"name":"NODE_0000034","node_attrs":{"div":50,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1.1"}},"branch_attrs":{"mutations":{"nuc":["G2591A","G3522A","C7771T","G14000T","G15428A","G21723A","G30367A","G31053A","G34459A","G37202A","G38360A","C38662T","G52885A","G54117A","G54635A","G64297A","C73066T","C82373T","G82451A","G95034A","G124674A","-133102T","C162331T","-173290A","-173291T","-173292A","-173293T","-173294A","-173295T","-173296A","-173297T","-173298A","-173299T","-173300A","-173301T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","G178133A","G181980A","G186578A","C193688T","C194619T"],"OPG002":["S54F"],"OPG002_dup":["S54F"],"OPG025":["A423D"],"OPG047":["R48C"],"OPG053":["P78S"],"OPG056":["E125K"],"OPG071":["L108F"],"OPG072":["D56N"],"OPG093":["S30L"],"OPG145":["R243Q"],"OPG210":["D209N","M1741I"]},"labels":{"aa":"OPG002: S54F; OPG002_dup: S54F; OPG025: A423D; OPG047: R48C; OPG053: P78S; OPG056: E125K; OPG071: L108F; OPG072: D56N; OPG093: S30L; OPG145: R243Q; OPG210: D209N, M1741I","clade":"A.1.1"}},"children":[{"name":"ON676708","node_attrs":{"div":53,"accession":"ON676708","author":{"author":"Gigante,C.M.,Myers,R.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Blythe,D.,Li,Y.","value":"Gigante,C.M.,Myers,R.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Blythe,D.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A.1.1"},"strain":{"value":"MPXV_USA_2021_MD"},"date":{"value":"2021-11-XX"},"strain_display":{"value":"USA/ON676708/2021-11-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C79348T","C86979T","C133714T","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"NODE_0000035","node_attrs":{"div":61,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G3111A","C39139T","G73239A","G74205A","G77383A","C84587T","C150469T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A151461C","G155795A","G170262A","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C183519T","C194099T"],"OPG057":["E353K"],"OPG093":["D88N"],"OPG094":["M142I"],"OPG098":["E162K"],"OPG176":["H221Y"],"OPG210":["P722S"]},"labels":{"aa":"OPG057: E353K; OPG093: D88N; OPG094: M142I; OPG098: E162K; OPG176: H221Y; OPG210: P722S","clade":"B.1"}},"children":[{"name":"LC722946","node_attrs":{"div":64,"accession":"LC722946","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Japan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/TKY220091/2022"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Japan/LC722946/2022-07-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C13653T","C116100T","G150376A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG025":["D539N"],"OPG176":["D190N"]},"labels":{"aa":"OPG025: D539N; OPG176: D190N"}}},{"name":"OP160532","node_attrs":{"div":62,"accession":"OP160532","author":{"author":"Tutu van Furth AM,van der Kuip M,van Els AL,Fievez LC,van Rijckevorsel GG,van den Ouden A,Jonges M,Welkers MR,Welkers,M.,Jonges,M.","value":"Tutu van Furth AM,van der Kuip M,van Els AL,Fievez LC,van Rijckevorsel GG,van den Ouden A,Jonges M,Welkers MR,Welkers,M.,Jonges,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Netherlands"},"clade_membership":{"value":"IIb"},"institution":{"value":"Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Netherlands/NH-AUMC-0001/2022"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Netherlands/OP160532/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A148207T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G191845A","A196614-"],"OPG173":["E57D"]},"labels":{"aa":"OPG173: E57D"}}},{"name":"OP150926","node_attrs":{"div":61,"accession":"OP150926","author":{"author":"Gigante,C.,Goldoft,M.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Holshue,M.,Li,Y.","value":"Gigante,C.,Goldoft,M.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Holshue,M.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_USA_2022_PA001"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/OP150926/2022-05-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP120938","node_attrs":{"div":63,"accession":"OP120938","author":{"author":"Aja-Macaya,P.,Rumbo-Feal,S.,Poza,M.,Canizares,A.,Vallejo,J.A.,Bou,G.","value":"Aja-Macaya,P.,Rumbo-Feal,S.,Poza,M.,Canizares,A.,Vallejo,J.A.,Bou,G."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Spain"},"clade_membership":{"value":"IIb"},"institution":{"value":"Biomedical research institute (INIBIC), Microbiology"},"lineage":{"value":"B.1"},"strain":{"value":"MP03CHUAC"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Spain/OP120938/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C118421T","C142607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG136":["M389I"],"OPG163":["H136Y"]},"labels":{"aa":"OPG136: M389I; OPG163: H136Y"}}},{"name":"OP019275","node_attrs":{"div":64,"accession":"OP019275","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Austria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV/Austria/MUW1525179/2022"},"date":{"value":"2022-06-10"},"strain_display":{"value":"Austria/OP019275/2022-06-10"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","A107070C","C144546T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G190319A","-196615A","-196616A","-196617A"],"OPG166":["S50F"]},"labels":{"aa":"OPG166: S50F"}}},{"name":"OP062230","node_attrs":{"div":62,"accession":"OP062230","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Jolly,G.,Griffiths,E.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Jolly,G.,Griffiths,E.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3864/2022"},"date":{"value":"2022-06-22"},"strain_display":{"value":"Canada/OP062230/2022-06-22"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C57790T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG077":["R265K"]},"labels":{"aa":"OPG077: R265K"}}},{"name":"ON843164","node_attrs":{"div":61,"accession":"ON843164","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0037/2022"},"date":{"value":"2022-05-18"},"strain_display":{"value":"Portugal/ON843164/2022-05-18"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C133103T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON872184","node_attrs":{"div":66,"accession":"ON872184","author":{"author":"Fletcher,N.,Gonzalez,G.,Meredith,L.,Purves,K.,Carr,M.,Dean,J.,Keogan,B.,Crowley,B.,Lyons,F.,O'Reilly,S.,Gautier,V.,Mallon,P.,Gordon,S.,Connell,J.,De Gascun,C.F.","value":"Fletcher,N.,Gonzalez,G.,Meredith,L.,Purves,K.,Carr,M.,Dean,J.,Keogan,B.,Crowley,B.,Lyons,F.,O'Reilly,S.,Gautier,V.,Mallon,P.,Gordon,S.,Connell,J.,De Gascun,C.F."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Ireland"},"clade_membership":{"value":"IIb"},"institution":{"value":"University College Dublin, National Virus Reference Laboratory"},"lineage":{"value":"B.1"},"strain":{"value":"WA-2022"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Ireland/ON872184/2022-05-30"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T48785C","G49636A","C50017T","T72809C","G178541A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG068":["G479E"],"OPG069":["T11I"],"OPG092":["K47E"]},"labels":{"aa":"OPG068: G479E; OPG069: T11I; OPG092: K47E"}}},{"name":"ON838940","node_attrs":{"div":61,"accession":"ON838940","author":{"author":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J.","value":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Spain"},"clade_membership":{"value":"IIb"},"institution":{"value":"Hospital Universitario La Paz, Microbiology"},"lineage":{"value":"B.1"},"strain":{"value":"4061"},"date":{"value":"2022-05-20"},"strain_display":{"value":"Spain/ON838940/2022-05-20"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON803426","node_attrs":{"div":61,"accession":"ON803426","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2856/2022"},"date":{"value":"2022-05-19"},"strain_display":{"value":"Canada/ON803426/2022-05-19"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON745215","node_attrs":{"div":61,"accession":"ON745215","author":{"author":"Giombini,E.,Gruber,C.E.M.,Rueca,M.,Gramigna,G.,VIta,S.,Carletti,F.,D'Abramo,A.,Lapa,D.,Puro,V.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Specchiarello,E.,Vairo,F.,Vaia,F.,Garbuglia,A.R.,Nicastri,E.,Antinori,A.,GIrardi,E.,Maggi,F.","value":"Giombini,E.,Gruber,C.E.M.,Rueca,M.,Gramigna,G.,VIta,S.,Carletti,F.,D'Abramo,A.,Lapa,D.,Puro,V.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Specchiarello,E.,Vairo,F.,Vaia,F.,Garbuglia,A.R.,Nicastri,E.,Antinori,A.,GIrardi,E.,Maggi,F."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Italy"},"clade_membership":{"value":"IIb"},"institution":{"value":"INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology"},"lineage":{"value":"B.1"},"strain":{"value":"INMI-Pt2"},"date":{"value":"2022-05-19"},"strain_display":{"value":"Italy/ON745215/2022-05-19"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T591A","A592-","T593-","T595A","-607T","-608T","-609T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A"]}}},{"name":"ON751962","node_attrs":{"div":64,"accession":"ON751962","author":{"author":"Claro,I.M.,de Lima,E.L.,Romano,C.M.,Candido,D.S.,Lindoso,J.A.L.,Barra,L.A.C.,Borges,L.M.S.,Medeiros,L.A.,Tomishige,M.Y.S.,Ramundo,M.S.,Moutinho,T.,da Silva,A.J.D.,Rodrigues,C.C.M.,de Azevedo,L.C.F.,Villas-Boas,L.S.,da Silva,C.A.M.,Coletti,T.M.,O'Toole,A.,Quick,J.,Loman,N.,Rambaut,A.,Faria,N.R.,Figueiredo-Mello,C.,Sabino,E.C.","value":"Claro,I.M.,de Lima,E.L.,Romano,C.M.,Candido,D.S.,Lindoso,J.A.L.,Barra,L.A.C.,Borges,L.M.S.,Medeiros,L.A.,Tomishige,M.Y.S.,Ramundo,M.S.,Moutinho,T.,da Silva,A.J.D.,Rodrigues,C.C.M.,de Azevedo,L.C.F.,Villas-Boas,L.S.,da Silva,C.A.M.,Coletti,T.M.,O'Toole,A.,Quick,J.,Loman,N.,Rambaut,A.,Faria,N.R.,Figueiredo-Mello,C.,Sabino,E.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Brazil"},"clade_membership":{"value":"IIb"},"institution":{"value":"Imperial College London, School of Public Health"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/BR0001/2022"},"date":{"value":"2022-06-07"},"strain_display":{"value":"Brazil/ON751962/2022-06-07"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G10118A","C15004T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G169928A","G173575-","A173576-","G173577-","A173578-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG021":["E178K"],"OPG197":["D87N"]},"labels":{"aa":"OPG021: E178K; OPG197: D87N"}}},{"name":"ON682269","node_attrs":{"div":61,"accession":"ON682269","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/RKI07"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/ON682269/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON615424","node_attrs":{"div":63,"accession":"ON615424","author":{"author":"Oude Munnink,B.B.,Boter,M.,Wellers,B.,Molenkamp,R.,Sikkema,R.S.,Koopmans,M.","value":"Oude Munnink,B.B.,Boter,M.,Wellers,B.,Molenkamp,R.,Sikkema,R.S.,Koopmans,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Netherlands"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Virology, Erasmus Medical Centre, The Netherlands"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_2022_NL001"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Netherlands/ON615424/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155611A","G171003A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","G179362-","G179363-","-196615A"],"OPG199":["E6K"]},"labels":{"aa":"OPG199: E6K"}}},{"name":"OP341487","node_attrs":{"div":65,"accession":"OP341487","author":{"author":"Welkers,M.,Jonges,M.,de Regt,M.,Ooijevaar,R.,Wagemakers,A.","value":"Welkers,M.,Jonges,M.,de Regt,M.,Ooijevaar,R.,Wagemakers,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Netherlands"},"clade_membership":{"value":"IIb"},"institution":{"value":"Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Netherlands/NH-AUMC-0060/2022"},"date":{"value":"2022-08-05"},"strain_display":{"value":"Netherlands/OP341487/2022-08-05"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C96773T","C109432T","C114985T","C142356T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG117":["S242L"],"OPG129":["D525N"],"OPG133":["D238N"],"OPG163":["S52F"]},"labels":{"aa":"OPG117: S242L; OPG129: D525N; OPG133: D238N; OPG163: S52F"}}},{"name":"OP324484","node_attrs":{"div":62,"accession":"OP324484","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0169/2022"},"date":{"value":"2022-07-03"},"strain_display":{"value":"Portugal/OP324484/2022-07-03"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C11787T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG023":["D372N"]},"labels":{"aa":"OPG023: D372N"}}},{"name":"OP215246","node_attrs":{"div":62,"accession":"OP215246","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/RKI210"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP215246/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C174842T"],"OPG204":["S104F"]},"labels":{"aa":"OPG204: S104F"}}},{"name":"OP205115","node_attrs":{"div":62,"accession":"OP205115","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_UK_2022_9000157"},"date":{"value":"2022-07-07"},"strain_display":{"value":"United Kingdom/OP205115/2022-07-07"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C78232T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP205123","node_attrs":{"div":62,"accession":"OP205123","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_UK_2022_9000167"},"date":{"value":"2022-06-30"},"strain_display":{"value":"United Kingdom/OP205123/2022-06-30"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C99954T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP422343","node_attrs":{"div":63,"accession":"OP422343","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Austria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV/Austria/MUW1540386/2022"},"date":{"value":"2022-08-08"},"strain_display":{"value":"Austria/OP422343/2022-08-08"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C102355T","C113923T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG121":["S189L"],"OPG133":["D592N"]},"labels":{"aa":"OPG121: S189L; OPG133: D592N"}}},{"name":"OP422245","node_attrs":{"div":61,"accession":"OP422245","author":{"author":"Laubscher,F.,Chudzinsk,V.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinsk,V.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Switzerland"},"clade_membership":{"value":"IIb"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV-CH-38212023/2022"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Switzerland/OP422245/2022-05-30"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OP415223","node_attrs":{"div":65,"accession":"OP415223","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1"},"strain":{"value":"MPX_jpMpSR_9000252"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415223/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C23567T","C67289T","G67527A","G77052A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG085":["E415K"]},"labels":{"aa":"OPG085: E415K"}}},{"name":"OP415194","node_attrs":{"div":61,"accession":"OP415194","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1"},"strain":{"value":"MPX_96X1Vd_9000216"},"date":{"value":"2022-03-XX"},"strain_display":{"value":"United Kingdom/OP415194/2022-03-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP414305","node_attrs":{"div":62,"accession":"OP414305","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0265/2022"},"date":{"value":"2022-06-17"},"strain_display":{"value":"Portugal/OP414305/2022-06-17"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","G25030A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"],"OPG040":["S150F"]},"labels":{"aa":"OPG040: S150F"}}},{"name":"OP382484","node_attrs":{"div":61,"accession":"OP382484","author":{"author":"Colson,P.","value":"Colson,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV-IHU00007"},"date":{"value":"2022-07-06"},"strain_display":{"value":"France/OP382484/2022-07-06"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP382478","node_attrs":{"div":62,"accession":"OP382478","author":{"author":"Colson,P.","value":"Colson,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV-IHU00001"},"date":{"value":"2022-06-13"},"strain_display":{"value":"France/OP382478/2022-06-13"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C178006T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG205":["S784F"]},"labels":{"aa":"OPG205: S784F"}}},{"name":"OP536811","node_attrs":{"div":63,"accession":"OP536811","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1"},"strain":{"value":"9000448"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536811/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C95004T","G111541A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG130":["S121F"]},"labels":{"aa":"OPG130: S121F"}}},{"name":"OP494265","node_attrs":{"div":63,"accession":"OP494265","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI374"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP494265/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C141266T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A153679T","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG180":["T330S"]},"labels":{"aa":"OPG180: T330S"}}},{"name":"OP587248","node_attrs":{"div":61,"accession":"OP587248","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDPH, VRDL"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-CDPH-MPX000019/2022"},"date":{"value":"2022-07-08"},"strain_display":{"value":"USA/OP587248/2022-07-08"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP555660","node_attrs":{"div":63,"accession":"OP555660","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0593/2022"},"date":{"value":"2022-09-14"},"strain_display":{"value":"Portugal/OP555660/2022-09-14"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C55859T","C93755T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG074":["V423I"]},"labels":{"aa":"OPG074: V423I"}}},{"name":"OP555573","node_attrs":{"div":63,"accession":"OP555573","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0499/2022"},"date":{"value":"2022-08-12"},"strain_display":{"value":"Portugal/OP555573/2022-08-12"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G2985A","C58850T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C194225T"],"OPG079":["E258K"]},"labels":{"aa":"OPG079: E258K"}}},{"name":"OP879743","node_attrs":{"div":61,"accession":"OP879743","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"lineage":{"value":"B.1"},"strain":{"value":"NJ-MPXV-027"},"date":{"value":"2022-06-29"},"strain_display":{"value":"USA/OP879743/2022-06-29"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP715825","node_attrs":{"div":63,"accession":"OP715825","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/RKI545"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OP715825/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G28706A","C38873T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG045":["P186L"],"OPG056":["M54I"]},"labels":{"aa":"OPG045: P186L; OPG056: M54I"}}},{"name":"OP693649","node_attrs":{"div":63,"accession":"OP693649","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1"},"strain":{"value":"ANT_INS_MPX_0039_L"},"date":{"value":"2022-07-29"},"strain_display":{"value":"Colombia/OP693649/2022-07-29"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A2840-","T2841-","C2842-","G127058A","G136194A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","T196865-","A196866-","G196867-"],"OPG148":["R358K"],"OPG153":["H492Y"]},"labels":{"aa":"OPG148: R358K; OPG153: H492Y"}}},{"name":"OQ411312","node_attrs":{"div":62,"accession":"OQ411312","author":{"author":"Laubscher,F.,Chudzinsk,V.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinsk,V.,Schibler,M.,Kaiser,L.,Renzoni,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Switzerland"},"clade_membership":{"value":"IIb"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV-CH-38292866/2022"},"date":{"value":"2022-06-08"},"strain_display":{"value":"Switzerland/OQ411312/2022-06-08"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C87764T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG109":["E562K"]},"labels":{"aa":"OPG109: E562K"}}},{"name":"OQ557951","node_attrs":{"div":66,"accession":"OQ557951","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_USA_2022_TX0003"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ557951/2022-10-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","C19610T","G108050A","T133102-","C135024T","C135225T","C156627T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-196615A"]}}},{"name":"OQ547873","node_attrs":{"div":62,"accession":"OQ547873","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDPH, VRDL"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000155/2022"},"date":{"value":"2022-12-15"},"strain_display":{"value":"USA/OQ547873/2022-12-15"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T620-","T621-","T622-","T6976-","G102694A","A140155T","A140156G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG159":["N130C"]},"labels":{"aa":"OPG159: N130C"}}},{"name":"OR030937","node_attrs":{"div":62,"accession":"OR030937","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_26"},"date":{"value":"2022-07-19"},"strain_display":{"value":"Belgium/OR030937/2022-07-19"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T98627C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG118":["V61A"]},"labels":{"aa":"OPG118: V61A"}}},{"name":"OQ973326","node_attrs":{"div":65,"accession":"OQ973326","author":{"author":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L.","value":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"lineage":{"value":"B.1"},"strain":{"value":"case1_air"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Belgium/OQ973326/2022-09-01"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","G2615-","A2616-","T2617-","A2618-","G2619-","A2620-","C2621-","A2622-","A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","T2653-","T2654-","T2655-","A2656-","C2657-","A2658-","C2659-","T2660-","T2661-","C111391T","C119654T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","C152191T","A173314-","T173315-","A173316-","T173317-","C176178T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A194549-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","A196613-","A196614-"],"OPG002":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-"],"OPG002_dup":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-"],"OPG130":["C171Y"],"OPG137":["S18L"],"OPG205":["H175Y"]},"labels":{"aa":"OPG002: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-; OPG002_dup: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-; OPG130: C171Y; OPG137: S18L; OPG205: H175Y"}}},{"name":"OQ918696","node_attrs":{"div":67,"accession":"OQ918696","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00485/2023"},"date":{"value":"2023-03-11"},"strain_display":{"value":"USA/OQ918696/2023-03-11"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G30285A","G37487A","C71193T","G119839A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C161690T","C177865T","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T179244-"],"OPG047":["P304S"],"OPG137":["E80K"],"OPG188":["S32F"],"OPG205":["S737F"]},"labels":{"aa":"OPG047: P304S; OPG137: E80K; OPG188: S32F; OPG205: S737F"}}},{"name":"OQ644777","node_attrs":{"div":65,"accession":"OQ644777","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00471/2023"},"date":{"value":"2023-02-13"},"strain_display":{"value":"USA/OQ644777/2023-02-13"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G2146A","A24345G","C39044T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T170904-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T187876C","C195064T"]}}},{"name":"OQ581849","node_attrs":{"div":63,"accession":"OQ581849","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Spain"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0007b/2022"},"date":{"value":"2022-07-05"},"strain_display":{"value":"Spain/OQ581849/2022-07-05"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A52777C","C150418T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T169409C","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG071":["Y554*"]},"labels":{"aa":"OPG071: Y554*"}}},{"name":"OQ570421","node_attrs":{"div":63,"accession":"OQ570421","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Italy"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"lineage":{"value":"B.1"},"strain":{"value":"INMI-22872022"},"date":{"value":"2022-08-22"},"strain_display":{"value":"Italy/OQ570421/2022-08-22"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C106275T","G111562A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG130":["S114F"]},"labels":{"aa":"OPG130: S114F"}}},{"name":"OR264423","node_attrs":{"div":62,"accession":"OR264423","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1"},"strain":{"value":"46_C"},"date":{"value":"2022-07-13"},"strain_display":{"value":"Australia/OR264423/2022-07-13"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","A41657-","C41658-","T41659-","A41660-","A41661-","T41662-","T41663-","T41664-","G41665-","T41666-","T41667-","T41668-","T41669-","A41670-","C41671-","T41672-","C41673-","T41674-","A41675-","T41676-","A41677-","C118161T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG061":["V72-","K73-","Q74-","I75-","S76-","I77-","S78-"],"OPG136":["R476Q"]},"labels":{"aa":"OPG061: V72-, K73-, Q74-, I75-, S76-, I77-, S78-; OPG136: R476Q"}}},{"name":"OR264404","node_attrs":{"div":66,"accession":"OR264404","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1"},"strain":{"value":"39_D"},"date":{"value":"2022-05-19"},"strain_display":{"value":"Australia/OR264404/2022-05-19"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C21128T","A22452T","C66718T","C144356T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188683T"],"OPG037":["E436K"],"OPG084":["S666L"]},"labels":{"aa":"OPG037: E436K; OPG084: S666L"}}},{"name":"OR095046","node_attrs":{"div":62,"accession":"OR095046","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Van Holm,B.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Van Holm,B.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_228/Belgium/2022'"},"date":{"value":"2022-08-12"},"strain_display":{"value":"Belgium/OR095046/2022-08-12"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133100-","T133101-","T133102-","C147965T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C196881-","G196882-","T196883-"],"OPG172":["S180F"]},"labels":{"aa":"OPG172: S180F"}}},{"name":"OR759186","node_attrs":{"div":65,"accession":"OR759186","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Canada/ON-PHOL098/2022"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759186/2022-09-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C77462T","C111164T","A143676G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C152385T"],"OPG098":["S188F"],"OPG130":["E247K"],"OPG165":["N54S"]},"labels":{"aa":"OPG098: S188F; OPG130: E247K; OPG165: N54S"}}},{"name":"OR759167","node_attrs":{"div":61,"accession":"OR759167","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Canada/ON-PHOL079/2022"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759167/2022-08-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR035713","node_attrs":{"div":61,"accession":"OR035713","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_107"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035713/2022-10-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP205139","node_attrs":{"div":61,"accession":"OP205139","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_UK_2022_9000090"},"date":{"value":"2022-05-25"},"strain_display":{"value":"United Kingdom/OP205139/2022-05-25"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON631241","node_attrs":{"div":61,"accession":"ON631241","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia"},"lineage":{"value":"B.1"},"strain":{"value":"2022/2 SLO"},"date":{"value":"2022-05-24"},"strain_display":{"value":"Slovenia/ON631241/2022-05-24"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON782022","node_attrs":{"div":61,"accession":"ON782022","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.,Sironen,T.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.,Sironen,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Finland"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"lineage":{"value":"B.1"},"strain":{"value":"MPX-42/Finland/2022"},"date":{"value":"2022-05-31"},"strain_display":{"value":"Finland/ON782022/2022-05-31"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"ON649879","node_attrs":{"div":61,"accession":"ON649879","author":{"author":"Israeli,O.,Guedj-Dana,Y.,Lazar,S.,Shifman,O.,Erez,N.,Weiss,S.,Paran,N.,Israely,T.,Schuster,O.,Zvi,A.,Beth-Din,A.,Cohen Gihon,I.","value":"Israeli,O.,Guedj-Dana,Y.,Lazar,S.,Shifman,O.,Erez,N.,Weiss,S.,Paran,N.,Israely,T.,Schuster,O.,Zvi,A.,Beth-Din,A.,Cohen Gihon,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Israel"},"clade_membership":{"value":"IIb"},"institution":{"value":"Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_ISR001_2022"},"date":{"value":"2022-05-20"},"strain_display":{"value":"Israel/ON649879/2022-05-20"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OR035655","node_attrs":{"div":61,"accession":"OR035655","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_49"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Belgium/OR035655/2022-05-30"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON563414","node_attrs":{"div":61,"accession":"ON563414","author":{"author":"Gigante,C.M.,Smole,S.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Brown,C.,Li,Y.","value":"Gigante,C.M.,Smole,S.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Brown,C.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_USA_2022_MA001"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/ON563414/2022-05-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON755040","node_attrs":{"div":61,"accession":"ON755040","author":{"author":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O.","value":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"IRBA, D.DNRBC/D.2MI/U.BACT"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_IRBA22-14"},"date":{"value":"2022-05-20"},"strain_display":{"value":"France/ON755040/2022-05-20"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000036","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C156429T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP019277","node_attrs":{"div":64,"accession":"OP019277","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Austria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV/Austria/MUW1531254/2022"},"date":{"value":"2022-07-04"},"strain_display":{"value":"Austria/OP019277/2022-07-04"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G162265A","C165278T"],"OPG188":["E224K"],"OPG190":["H53Y"]},"labels":{"aa":"OPG188: E224K; OPG190: H53Y"}}},{"name":"OP270023","node_attrs":{"div":66,"accession":"OP270023","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3975/2022"},"date":{"value":"2022-07-04"},"strain_display":{"value":"Canada/OP270023/2022-07-04"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G40625A","C65571T","C134205T","G144988A","-196615A"]}}}]},{"name":"NODE_0000037","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["A87268G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG109":["V727A"]},"labels":{"aa":"OPG109: V727A"}},"children":[{"name":"ON929076","node_attrs":{"div":63,"accession":"ON929076","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/RKI121"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/ON929076/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C141757T"]}}},{"name":"OP689663","node_attrs":{"div":64,"accession":"OP689663","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI510"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"Germany/OP689663/2022-10-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G84579A","G115865A"],"OPG105":["D1152N"],"OPG134":["R39K"]},"labels":{"aa":"OPG105: D1152N; OPG134: R39K"}}}]},{"name":"NODE_0000038","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C36405T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG055":["A227T"]},"labels":{"aa":"OPG055: A227T"}},"children":[{"name":"OP837473","node_attrs":{"div":67,"accession":"OP837473","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1"},"strain":{"value":"VAC_INS_MPX_1054_L"},"date":{"value":"2022-10-25"},"strain_display":{"value":"Colombia/OP837473/2022-10-25"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C33082T","C40849T","G68103A","G117233A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C180361T","A197043-","T197044-","G197045-"],"OPG049":["D24N"],"OPG060":["E112K"]},"labels":{"aa":"OPG049: D24N; OPG060: E112K"}}},{"name":"OQ320447","node_attrs":{"div":65,"accession":"OQ320447","author":{"author":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y.","value":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_USA_2022_DC0018"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ320447/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","C14226T","C46679T","C181816T","A196613-","A196614-"],"OPG025":["D348N"],"OPG210":["S154L"]},"labels":{"aa":"OPG025: D348N; OPG210: S154L"}}}]},{"name":"NODE_0000039","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C127215T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG149":["S7L"]},"labels":{"aa":"OPG149: S7L"}},"children":[{"name":"OQ148466","node_attrs":{"div":66,"accession":"OQ148466","author":{"author":"Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"lineage":{"value":"B.1"},"strain":{"value":"LBMB-UTP_MP-009_TOL"},"date":{"value":"2022-09-13"},"strain_display":{"value":"Colombia/OQ148466/2022-09-13"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G57907A","C105991T","C114157T","G175662A"],"OPG077":["S226L"],"OPG133":["E514K"],"OPG205":["E3K"]},"labels":{"aa":"OPG077: S226L; OPG133: E514K; OPG205: E3K"}}},{"name":"OR035705","node_attrs":{"div":63,"accession":"OR035705","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_99"},"date":{"value":"2022-06-02"},"strain_display":{"value":"Belgium/OR035705/2022-06-02"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C142797T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG164":["S7L"]},"labels":{"aa":"OPG164: S7L"}}}]},{"name":"NODE_0000040","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C53342T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG071":["R366K"]},"labels":{"aa":"OPG071: R366K"}},"children":[{"name":"OQ451902","node_attrs":{"div":67,"accession":"OQ451902","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/RKI717"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"Germany/OQ451902/2022-11-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","C3602T","C124495T","G159789A","C170573T","G190695A","G193608A"],"OPG003":["E336K"],"OPG003_dup":["E336K"],"OPG016":["E96K"],"OPG198":["S179L"]},"labels":{"aa":"OPG003: E336K; OPG003_dup: E336K; OPG016: E96K; OPG198: S179L"}}},{"name":"OQ331002","node_attrs":{"div":64,"accession":"OQ331002","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00374/2022"},"date":{"value":"2022-11-23"},"strain_display":{"value":"USA/OQ331002/2022-11-23"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C109535T","A136516-","T136517-","C156205T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196657-","T196658-","A196659-"]}}}]},{"name":"NODE_0000041","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G160358A"]}},"children":[{"name":"OQ503799","node_attrs":{"div":70,"accession":"OQ503799","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00411/2023"},"date":{"value":"2023-01-04"},"strain_display":{"value":"USA/OQ503799/2023-01-04"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G1512A","G12099A","G44107A","A60659T","G107064A","C143551T","G145790A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C188361T","C195698T"],"OPG001":["Q22*"],"OPG001_dup":["Q22*"],"OPG023":["R268*"],"OPG080":["F454I"]},"labels":{"aa":"OPG001: Q22*; OPG001_dup: Q22*; OPG023: R268*; OPG080: F454I"}}},{"name":"OQ721951","node_attrs":{"div":64,"accession":"OQ721951","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Taiwan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/human/Taiwan/110-122438/2023"},"date":{"value":"2023-03-XX"},"strain_display":{"value":"Taiwan/OQ721951/2023-03-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133092-","T133093-","T133094-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T149983A","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A184479G","G193496T","A193498T","A193748G","T194019G","T194021A","G194086A"],"OPG003_dup":["K298N","E299V","C473G","R495K"],"OPG176":["S59T"],"OPG210":["R1042G"]},"labels":{"aa":"OPG003_dup: K298N, E299V, C473G, R495K; OPG176: S59T; OPG210: R1042G"}}}]},{"name":"NODE_0000042","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T606-","G67955A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G184141A","A196614-"],"OPG085":["P193S"],"OPG210":["G929D"]},"labels":{"aa":"OPG085: P193S; OPG210: G929D"}},"children":[{"name":"OX291780","node_attrs":{"div":63,"accession":"OX291780","outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovakia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"lineage":{"value":"B.1"},"strain":{"value":"RNA"},"date":{"value":"2022-07-25"},"strain_display":{"value":"Slovakia/OX291780/2022-07-25"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A173316-","T173317-"]}}},{"name":"OX291676","node_attrs":{"div":64,"accession":"OX291676","outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovakia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"lineage":{"value":"B.1"},"strain":{"value":"RNA"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Slovakia/OX291676/2022-08-01"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G14590A","T133102-"]}}}]},{"name":"NODE_0000043","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C34784T","C101418T","G109844A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG054":["D405N"],"OPG120":["D111N"]},"labels":{"aa":"OPG054: D405N; OPG120: D111N"}},"children":[{"name":"OR743498","node_attrs":{"div":67,"accession":"OR743498","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1029"},"date":{"value":"2023-10-XX"},"strain_display":{"value":"Germany/OR743498/2023-10-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C45528T","C84767T","C170791T"],"OPG064":["R124K"]},"labels":{"aa":"OPG064: R124K"}}},{"name":"OR743494","node_attrs":{"div":64,"accession":"OR743494","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1025"},"date":{"value":"2023-09-XX"},"strain_display":{"value":"Germany/OR743494/2023-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G179263-","C179264-"]}}}]},{"name":"NODE_0000044","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G62109-","A62110-","T62111-","A62112-","A62113-","A62114-","G62115-","A62116-","G62117-","T62118-","C62119-","C62120-","T62121-","A62122-","T62123-","A62124-","T62125-","A62126-","T62127-","T62128-","T62129-","G62130-","A62131-","A62132-","A62133-","A62134-","T62135-","C62136-","G62137-","T62138-","T62139-","A62140-","C62141-","G62142-","G62143-","T62144-","T62145-","C62146-","G62147-","A62148-","T62149-","T62150-","A62151-","C62166-","A62167-","T62168-","T62169-","G62170-","T62171-","G62172-","A62173-","A62174-","T62175-","A62176-","T62177-","A62178-","T62179-","C62180-","A62181-","T62182-","T62183-","A62184-","G62185-","G62186-","A62187-","T62188-","T62189-","T62190-","A62191-","A62192-","C62193-","T62194-","C62195-","C62196-","T62197-","T62198-","G62199-","A62200-","C62201-","T62202-","A62203-","T62204-","C62205-","A62206-","T62207-","G62208-","G62209-","C62210-","G62211-","G62212-","T62213-","G62214-","C62215-","C62216-","A62217-","G62218-","A62219-","A62220-","A62221-","T62222-","T62223-","A62224-","C62225-","C62226-","A62227-","T62228-","C62229-","A62230-","A62231-","A62232-","A62233-","G62234-","C62235-","A62236-","T62237-","T62238-","A62239-","A62240-","T62241-","A62242-","C62243-","A62244-","G62245-","T62246-","T62247-","A62248-","T62249-","G62250-","C62251-","A62252-","G62253-","A62254-","T62255-","C62256-","G62257-","C62258-","A62259-","G62260-","T62261-","T62262-","A62263-","G62264-","A62265-","A62266-","C62267-","G62268-","G62269-","T62270-","T62271-","A62272-","T62273-","A62274-","G62275-","C62276-","A62277-","T62278-","C62279-","C62280-","A62281-","C62282-","C62283-","A62284-","T62285-","T62286-","T62287-","A62288-","T62289-","A62290-","T62291-","C62292-","T62293-","A62303-","T62304-","C62305-","A62306-","A62307-","A62308-","G62309-","A62310-","A62311-","T62312-","A62313-","T62314-","G62315-","T62316-","G62317-","A62318-","C62319-","A62320-","A62321-","C62322-","G62323-","T62324-","C62325-","C62326-","T62327-","A62328-","G62329-","T62330-","T62331-","G62332-","T62333-","A62334-","T62335-","A62336-","C62337-","T62338-","G62339-","A62340-","G62341-","A62342-","A62343-","T62344-","T62345-","G62346-","A62347-","C62348-","G62349-","A62350-","A62351-","A62352-","C62353-","A62354-","A62355-","T62356-","G62357-","C62376-","T62377-","T62378-","A62379-","T62380-","T62381-","A62382-","G62383-","T62384-","A62385-","A62386-","C62387-","C62388-","G62389-","A62390-","C62391-","T62392-","T62393-","A62394-","A62395-","T62396-","A62397-","G62398-","T62399-","A62400-","G62401-","G62402-","A62403-","A62404-","C62405-","T62406-","G62407-","G62408-","A62409-","A62410-","A62411-","A62412-","C62413-","T62414-","A62415-","G62416-","A62417-","C62418-","T62419-","T62420-","G62421-","A62422-","T62423-","T62424-","A62425-","T62426-","T62427-","C62428-","T62429-","A62430-","T62431-","A62432-","A62433-","G62434-","T62435-","A62436-","T62437-","A62438-","G62439-","A62440-","T62441-","A62442-","C62443-","C62444-","C62445-","T62446-","T62447-","C62448-","C62449-","A62450-","A62451-","A62452-","T62453-","A62454-","A62455-","T62456-","G62457-","T62458-","T62459-","C62460-","T62461-","C62462-","T62463-","T62464-","T62465-","G62466-","A62467-","T62468-","A62469-","A62470-","A62471-","A62472-","G62473-","T62474-","T62475-","C62476-","C62477-","A62478-","G62479-","A62480-","A62481-","A62482-","A62483-","T62484-","G62485-","T62486-","A62487-","G62488-","A62489-","A62490-","T62491-","T62492-","T62493-","T62494-","T62495-","T62496-","A62497-","A62498-","A62499-","A62500-","A62501-","G62502-","T62503-","T62504-","A62505-","T62506-","C62507-","T62508-","T62509-","T62510-","T62511-","G62512-","C62513-","T62514-","A62515-","T62516-","T62517-","A62518-","C62519-","T62520-","A62521-","A62522-","T62523-","A62524-","T62525-","C62526-","G62527-","T62528-","G62529-","G62530-","T62531-","T62532-","A62533-","G62534-","A62535-","C62536-","G62537-","C62538-","T62539-","T62540-","A62541-","T62542-","T62543-","A62544-","T62545-","T62546-","A62547-","A62548-","T62549-","A62550-","T62551-","G62552-","A62553-","G62554-","T62555-","G62556-","A62557-","T62558-","G62559-","A62560-","A62561-","A62562-","T62563-","C62564-","C62565-","A62566-","C62567-","A62568-","C62569-","C62570-","G62571-","C62572-","T62573-","T62574-","C62575-","T62576-","A62577-","G62578-","A62579-","T62580-","A62581-","T62582-","C62583-","G62584-","C62585-","T62586-","T62587-","T62588-","T62589-","A62590-","T62591-","T62592-","T62593-","C62594-","C62595-","A62596-","C62597-","A62598-","T62599-","T62600-","A62601-","G62602-","A62603-","T62604-","G62605-","G62606-","T62607-","A62608-","A62609-","A62610-","T62611-","C62612-","C62613-","A62614-","A62615-","T62616-","A62617-","G62618-","T62619-","G62620-","A62621-","A62622-","A62623-","C62624-","T62625-","A62626-","T62627-","C62628-","T62629-","T62630-","A62703-","T62704-","A62705-","A62706-","A62707-","C62708-","A62709-","A62710-","T62711-","T62712-","T62713-","C62714-","A62715-","C62716-","A62717-","A62718-","A62719-","T62720-","G62721-","G62722-","A62723-","T62724-","G62725-","T62726-","T62727-","A62728-","A62729-","T62730-","G62731-","T62732-","A62733-","T62734-","T62735-","A62736-","G62737-","T62738-","A62739-","G62740-","G62741-","A62742-","A62743-","A62744-","T62745-","T62746-","T62747-","T62748-","T62749-","T62750-","G62751-","A62752-","C62753-","G62754-","C62755-","T62756-","A62757-","G62758-","T62759-","G62760-","G62761-","A62762-","A62763-","T62764-","T62765-","G62766-","A62767-","A62768-","G62769-","A62770-","T62771-","T62772-","C62773-","T62774-","A62775-","A62776-","T62777-","G62778-","G62779-","A62780-","T62781-","G62782-","A62783-","T62784-","G62785-","T62786-","T62787-","C62788-","T62789-","A62790-","C62791-","C62792-","T62793-","A62794-","T62795-","T62796-","T62797-","C62798-","A62799-","T62800-","C62801-","C62802-","G62803-","A62804-","T62805-","A62806-","A62807-","C62808-","A62809-","T62810-","G62811-","T62812-","T62813-","A62814-","A62815-","T62816-","T62817-","T62818-","C62819-","C62820-","A62821-","A62822-","T62823-","A62824-","C62825-","C62826-","A62827-","A62828-","C62829-","G62830-","G62831-","T62832-","T62833-","T62834-","T62835-","A62836-","A62837-","T62838-","A62839-","T62840-","T62841-","T62842-","C62843-","G62844-","A62845-","T62846-","G62847-","A62848-","T62849-","A62850-","T62851-","A62852-","C62853-","G62854-","G62855-","T62856-","A62857-","G62858-","T62859-","C62860-","T62861-","C62862-","T62863-","C62864-","T62865-","T62866-","T62867-","C62868-","G62869-","G62870-","A62871-","C62872-","T62873-","T62874-","A62875-","T62876-","A62877-","T62878-","A62879-","G62880-","C62881-","T62882-","T62883-","A62884-","T62885-","T62886-","C62887-","C62888-","A62889-","C62890-","A62891-","A62892-","T62893-","A62894-","C62895-","G62896-","A62897-","G62898-","T62899-","C62900-","A62901-","T62902-","T62903-","A62904-","T62905-","A62906-","T62907-","A62908-","C62909-","T62910-","C62911-","C62912-","A62913-","A62914-","A62915-","A62916-","A62917-","A62918-","C62919-","A62920-","A62921-","A62922-","A62923-","T62924-","A62925-","A62926-","C62927-","T62928-","A62929-","G62930-","T62931-","A62932-","T62933-","A62934-","A62935-","A62936-","A62937-","T62938-","C62939-","T62940-","G62941-","T62942-","A62943-","T62944-","C62945-","G62946-","A62947-","A62948-","T62949-","G62950-","G62951-","G62952-","A62953-","A62954-","A62955-","A62956-","A62957-","C62958-","G62959-","A62960-","A62961-","A62962-","T62963-","T62964-","A62965-","T62966-","C62967-","G62968-","A62969-","T62970-","A62971-","T62972-","A62973-","G62974-","G62975-","T62976-","A62977-","T62978-","A62979-","G62980-","A62981-","A62982-","T62983-","C62984-","C62985-","G62986-","G62987-","A62988-","A62989-","C62990-","A62991-","T62992-","T62993-","G62994-","A62995-","A62996-","C62997-","G62998-","T62999-","A63000-","T63001-","T63002-","A63003-","A63004-","T63005-","A63006-","C63007-","T63008-","T63009-","A63010-","A63011-","T63012-","T63013-","C63014-","T63015-","T63016-","T63017-","T63018-","T63019-","C63020-","A63021-","G63022-","T63023-","G63024-","G63025-","T63026-","A63027-","A63028-","G63029-","A63030-","A63031-","C63032-","C63033-","G63034-","A63035-","T63036-","A63037-","G63038-","G63039-","T63040-","T63041-","A63042-","T63043-","T63044-","G63045-","A63046-","C63047-","A63048-","T63049-","T63050-","G63051-","T63052-","A63053-","T63054-","G63055-","G63056-","T63057-","T63058-","T63059-","T63060-","A63061-","A63062-","A63063-","T63064-","A63065-","T63066-","T63067-","C63068-","T63069-","A63070-","T63071-","A63072-","A63073-","C63074-","T63075-","T63076-","G63077-","A63078-","G63079-","A63080-","C63081-","T63082-","T63083-","G63084-","A63085-","T63086-","A63087-","G63088-","A63089-","T63090-","A63091-","T63092-","T63093-","A63094-","A63095-","T63096-","G63097-","A63098-","C63099-","G63100-","A63101-","A63102-","T63103-","T63104-","G63105-","A63106-","A63107-","A63108-","A63109-","T63110-","T63111-","A63112-","T63113-","T63114-","T63115-","T63116-","T63117-","A63118-","T63119-","C63120-","A63121-","C63122-","C63123-","A63124-","C63125-","G63126-","T63127-","G63128-","T63129-","G63130-","T63131-","T63132-","T63133-","C63134-","A63135-","G63136-","G63137-","A63138-","T63139-","C63140-","A63141-","T63142-","C63143-","G63144-","T63145-","C63146-","G63147-","A63148-","C63149-","G63150-","C63151-","C63152-","A63153-","G63154-","T63155-","T63156-","A63157-","A63158-","C63159-","C63160-","A63161-","A63162-","C63163-","C63164-","G63165-","A63166-","A63167-","T63168-","G63169-","G63170-","A63171-","G63172-","T63173-","A63174-","A63175-","A63176-","A63177-","T63178-","A63179-","A63180-","A63181-","T63182-","A63183-","T63184-","C63185-","A63186-","T63187-","T63188-","A63189-","A63190-","T63191-","A63192-","T63193-","A63194-","T63195-","G63196-","C63197-","T63198-","C63199-","T63200-","A63201-","G63202-","A63203-","T63204-","A63205-","T63206-","T63207-","A63208-","G63209-","T63210-","A63211-","T63212-","T63213-","T63214-","T63215-","T63216-","A63217-","T63218-","T63219-","A63220-","A63221-","T63222-","C63223-","C63224-","T63225-","T63226-","T63227-","G63228-","A63229-","T63230-","T63231-","A63232-","T63233-","C63234-","A63235-","T63236-","C63237-","T63238-","T63239-","C63240-","T63241-","C63242-","G63243-","T63244-","A63245-","C63246-","G63247-","C63248-","G63249-","A63250-","A63251-","T63252-","G63253-","A63254-","T63255-","T63256-","C63257-","C63258-","A63259-","T63260-","G63261-","A63262-","T63263-","C63264-","A63265-","A63266-","G63267-","A63268-","G63269-","T63270-","G63271-","A63272-","T63273-","T63274-","T63275-","G63276-","A63277-","G63278-","A63279-","A63280-","C63281-","A63282-","T63283-","C63284-","C63285-","T63286-","C63287-","C63288-","G63289-","G63290-","A63291-","G63292-","T63293-","A63294-","T63295-","T63296-","A63297-","A63298-","T63299-","G63300-","G63301-","G63302-","T63303-","T63304-","T63305-","A63306-","G63307-","T63308-","A63309-","A63310-","A63311-","C63312-","A63313-","G63314-","T63315-","C63316-","C63317-","A63318-","T63319-","C63320-","G63321-","T63322-","T63323-","G63324-","C63325-","A63326-","A63327-","T63328-","A63329-","A63330-","T63331-","A63332-","A63333-","A63334-","A63335-","G63336-","T63337-","T63338-","G63339-","T63340-","C63341-","C63342-","A63343-","A63344-","G63345-","T63346-","T63347-","A63348-","A63349-","A63350-","G63351-","G63352-","A63353-","T63354-","A63355-","T63356-","T63357-","A63358-","T63359-","G63360-","C63361-","A63362-","T63363-","T63364-","C63365-","G63366-","T63367-","T63368-","T63369-","A63370-","A63371-","A63372-","G63373-","A63374-","T63375-","A63376-","T63377-","C63378-","A63379-","C63380-","C63381-","T63382-","C63383-","A63384-","T63385-","C63386-","T63387-","A63388-","A63389-","C63390-","G63391-","G63392-","A63393-","G63394-","A63395-","C63396-","A63397-","A63398-","T63399-","T63400-","T63401-","T63402-","T63403-","T63404-","G63405-","G63406-","T63407-","A63408-","G63409-","G63410-","T63411-","T63412-","T63413-","T63414-","A63415-","G63416-","A63417-","G63418-","A63419-","C63420-","T63421-","T63422-","T63423-","G63424-","A63425-","A63426-","G63427-","C63428-","T63429-","A63430-","C63431-","T63432-","T63433-","G63434-","T63435-","T63436-","T63437-","A63438-","A63439-","C63440-","A63441-","A63442-","A63443-","G63444-","T63445-","T63446-","A63447-","T63448-","T63449-","C63450-","A63451-","T63452-","C63453-","G63454-","T63455-","C63456-","G63457-","T63458-","C63459-","T63460-","A63461-","C63462-","T63463-","A63464-","T63465-","T63466-","C63467-","T63468-","A63469-","T63470-","T63471-","T63472-","A63473-","A63474-","T63475-","T63476-","T63477-","T63478-","G63479-","T63480-","A63481-","G63482-","T63483-","T63484-","A63485-","A63486-","T63487-","T63488-","T63489-","A63490-","T63491-","C63492-","A63493-","C63494-","A63495-","T63496-","A63497-","T63498-","C63499-","A63500-","C63501-","A63502-","T63503-","T63504-","C89166T","C112408T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG131":["L157F"]},"labels":{"aa":"OPG131: L157F"}},"children":[{"name":"OQ672570","node_attrs":{"div":63,"accession":"OQ672570","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"lineage":{"value":"B.1"},"strain":{"value":"02112022_anal"},"date":{"value":"2022-11-02"},"strain_display":{"value":"Belgium/OQ672570/2022-11-02"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G47746-","G49680-","G49710-","A62294-","A62295-","A62296-","A62297-","A62298-","T62299-","T62300-","A62301-","G62302-","T62358-","T62359-","T62360-","C62361-","T62362-","T62363-","A62364-","C62365-","A62366-","T62367-","A62368-","T62369-","T62370-","T62371-","T62372-","T62373-","T62374-","T62375-"],"OPG068":["D494-"],"OPG081":["N46-","R47-","T48-","V49-","T50-","I51-","F52-","K53-","Y54-","I55-","G56-","L57-","F58-","I59-"]},"labels":{"aa":"OPG068: D494-; OPG081: N46-, R47-, T48-, V49-, T50-, I51-, F52-, K53-, Y54-, I55-, G56-, L57-, F58-, I59-"}}},{"name":"NODE_0000045","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","G187391A","A194549-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-"],"OPG002":["R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-","C47-"],"OPG002_dup":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-"]},"labels":{"aa":"OPG002: R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-, C47-; OPG002_dup: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-"}},"children":[{"name":"OQ672572","node_attrs":{"div":64,"accession":"OQ672572","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"lineage":{"value":"B.1"},"strain":{"value":"26012023_anal"},"date":{"value":"2023-01-26"},"strain_display":{"value":"Belgium/OQ672572/2023-01-26"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-62109G","-62110A","-62111T","-62112A","-62113A","-62114A","-62115G","-62116A","-62117G","-62118T","-62119C","-62120C","-62121T","-62122A","-62123T","-62124A","-62125T","-62126A","-62127T","-62128T","-62129T","-62130G","-62131A","-62132A","-62133A","-62134A","-62135T","-62136C","-62137G","-62138T","-62139T","-62140A","-62141C","-62142G","-62143G","-62144T","-62145T","-62146C","-62147G","-62148A","-62149T","-62150T","-62151A","-62166C","-62167A","-62168T","-62169T","-62170G","-62171T","-62172G","-62173A","-62174A","-62175T","-62176A","-62177T","-62178A","-62179T","-62180C","-62181A","-62182T","-62183T","-62184A","-62185G","-62186G","-62187A","-62188T","-62189T","-62190T","-62191A","-62192A","-62193C","-62194T","-62195C","-62196C","-62197T","-62198T","-62199G","-62200A","-62201C","-62202T","-62203A","-62204T","-62205C","-62206A","-62207T","-62208G","-62209G","-62210C","-62211G","-62212G","-62213T","-62214G","-62215C","-62216C","-62217A","-62218G","-62219A","-62220A","-62221A","-62222T","-62223T","-62224A","-62225C","-62226C","-62227A","-62228T","-62229C","-62230A","-62231A","-62232A","-62233A","-62234G","-62235C","-62236A","-62237T","-62238T","-62239A","-62240A","-62241T","-62242A","-62243C","-62244A","-62245G","-62246T","-62247T","-62248A","-62249T","-62250G","-62251C","-62252A","-62253G","-62254A","-62255T","-62256C","-62257G","-62258C","-62259A","-62260G","-62261T","-62262T","-62263A","-62264G","-62265A","-62266A","-62267C","-62268G","-62269G","-62270T","-62271T","-62272A","-62273T","-62274A","-62275G","-62276C","-62277A","-62278T","-62279C","-62280C","-62281A","-62282C","-62283C","-62284A","-62285T","-62286T","-62287T","-62288A","-62289T","-62290A","-62291T","-62292C","-62293T","-62303A","-62304T","-62305C","-62306A","-62307A","-62308A","-62309G","-62310A","-62311A","-62312T","-62313A","-62314T","-62315G","-62316T","-62317G","-62318A","-62319C","-62320A","-62321A","-62322C","-62323G","-62324T","-62325C","-62326C","-62327T","-62328A","-62329G","-62330T","-62331T","-62332G","-62333T","-62334A","-62335T","-62336A","-62337C","-62338T","-62339G","-62340A","-62341G","-62342A","-62343A","-62344T","-62345T","-62346G","-62347A","-62348C","-62349G","-62350A","-62351A","-62352A","-62353C","-62354A","-62355A","-62356T","-62357G","-62376C","-62377T","-62378T","-62379A","-62380T","-62381T","-62382A","-62383G","-62384T","-62385A","-62386A","-62387C","-62388C","-62389G","-62390A","-62391C","-62392T","-62393T","-62394A","-62395A","-62396T","-62397A","-62398G","-62399T","-62400A","-62401G","-62402G","-62403A","-62404A","-62405C","-62406T","-62407G","-62408G","-62409A","-62410A","-62411A","-62412A","-62413C","-62414T","-62415A","-62416G","-62417A","-62418C","-62419T","-62420T","-62421G","-62422A","-62423T","-62424T","-62425A","-62426T","-62427T","-62428C","-62429T","-62430A","-62431T","-62432A","-62433A","-62434G","-62435T","-62436A","-62437T","-62438A","-62439G","-62440A","-62441T","-62442A","-62443C","-62444C","-62445C","-62446T","-62447T","-62448C","-62449C","-62450A","-62451A","-62452A","-62453T","-62454A","-62455A","-62456T","-62457G","-62458T","-62459T","-62460C","-62461T","-62462C","-62463T","-62464T","-62465T","-62466G","-62467A","-62468T","-62469A","-62470A","-62471A","-62472A","-62473G","-62474T","-62475T","-62476C","-62477C","-62478A","-62479G","-62480A","-62481A","-62482A","-62483A","-62484T","-62485G","-62486T","-62487A","-62488G","-62489A","-62490A","-62491T","-62492T","-62493T","-62494T","-62495T","-62496T","-62497A","-62498A","-62499A","-62500A","-62501A","-62502G","-62503T","-62504T","-62505A","-62506T","-62507C","-62508T","-62509T","-62510T","-62511T","-62512G","-62513C","-62514T","-62515A","-62516T","-62517T","-62518A","-62519C","-62520T","-62521A","-62522A","-62523T","-62524A","-62525T","-62526C","-62527G","-62528T","-62529G","-62530G","-62531T","-62532T","-62533A","-62534G","-62535A","-62536C","-62537G","-62538C","-62539T","-62540T","-62541A","-62542T","-62543T","-62544A","-62545T","-62546T","-62547A","-62548A","-62549T","-62550A","-62551T","-62552G","-62553A","-62554G","-62555T","-62556G","-62557A","-62558T","-62559G","-62560A","-62561A","-62562A","-62563T","-62564C","-62565C","-62566A","-62567C","-62568A","-62569C","-62570C","-62571G","-62572C","-62573T","-62574T","-62575C","-62576T","-62577A","-62578G","-62579A","-62580T","-62581A","-62582T","-62583C","-62584G","-62585C","-62586T","-62587T","-62588T","-62589T","-62590A","-62591T","-62592T","-62593T","-62594C","-62595C","-62596A","-62597C","-62598A","-62599T","-62600T","-62601A","-62602G","-62603A","-62604T","-62605G","-62606G","-62607T","-62608A","-62609A","-62610A","-62611T","-62612C","-62613C","-62614A","-62615A","-62616T","-62617A","-62618G","-62619T","-62620G","-62621A","-62622A","-62623A","-62624C","-62625T","-62626A","-62627T","-62628C","-62629T","-62630T","-62703A","-62704T","-62705A","-62706A","-62707A","-62708C","-62709A","-62710A","-62711T","-62712T","-62713T","-62714C","-62715A","-62716C","-62717A","-62718A","-62719A","-62720T","-62721G","-62722G","-62723A","-62724T","-62725G","-62726T","-62727T","-62728A","-62729A","-62730T","-62731G","-62732T","-62733A","-62734T","-62735T","-62736A","-62737G","-62738T","-62739A","-62740G","-62741G","-62742A","-62743A","-62744A","-62745T","-62746T","-62747T","-62748T","-62749T","-62750T","-62751G","-62752A","-62753C","-62754G","-62755C","-62756T","-62757A","-62758G","-62759T","-62760G","-62761G","-62762A","-62763A","-62764T","-62765T","-62766G","-62767A","-62768A","-62769G","-62770A","-62771T","-62772T","-62773C","-62774T","-62775A","-62776A","-62777T","-62778G","-62779G","-62780A","-62781T","-62782G","-62783A","-62784T","-62785G","-62786T","-62787T","-62788C","-62789T","-62790A","-62791C","-62792C","-62793T","-62794A","-62795T","-62796T","-62797T","-62798C","-62799A","-62800T","-62801C","-62802C","-62803G","-62804A","-62805T","-62806A","-62807A","-62808C","-62809A","-62810T","-62811G","-62812T","-62813T","-62814A","-62815A","-62816T","-62817T","-62818T","-62819C","-62820C","-62821A","-62822A","-62823T","-62824A","-62825C","-62826C","-62827A","-62828A","-62829C","-62830G","-62831G","-62832T","-62833T","-62834T","-62835T","-62836A","-62837A","-62838T","-62839A","-62840T","-62841T","-62842T","-62843C","-62844G","-62845A","-62846T","-62847G","-62848A","-62849T","-62850A","-62851T","-62852A","-62853C","-62854G","-62855G","-62856T","-62857A","-62858G","-62859T","-62860C","-62861T","-62862C","-62863T","-62864C","-62865T","-62866T","-62867T","-62868C","-62869G","-62870G","-62871A","-62872C","-62873T","-62874T","-62875A","-62876T","-62877A","-62878T","-62879A","-62880G","-62881C","-62882T","-62883T","-62884A","-62885T","-62886T","-62887C","-62888C","-62889A","-62890C","-62891A","-62892A","-62893T","-62894A","-62895C","-62896G","-62897A","-62898G","-62899T","-62900C","-62901A","-62902T","-62903T","-62904A","-62905T","-62906A","-62907T","-62908A","-62909C","-62910T","-62911C","-62912C","-62913A","-62914A","-62915A","-62916A","-62917A","-62918A","-62919C","-62920A","-62921A","-62922A","-62923A","-62924T","-62925A","-62926A","-62927C","-62928T","-62929A","-62930G","-62931T","-62932A","-62933T","-62934A","-62935A","-62936A","-62937A","-62938T","-62939C","-62940T","-62941G","-62942T","-62943A","-62944T","-62945C","-62946G","-62947A","-62948A","-62949T","-62950G","-62951G","-62952G","-62953A","-62954A","-62955A","-62956A","-62957A","-62958C","-62959G","-62960A","-62961A","-62962A","-62963T","-62964T","-62965A","-62966T","-62967C","-62968G","-62969A","-62970T","-62971A","-62972T","-62973A","-62974G","-62975G","-62976T","-62977A","-62978T","-62979A","-62980G","-62981A","-62982A","-62983T","-62984C","-62985C","-62986G","-62987G","-62988A","-62989A","-62990C","-62991A","-62992T","-62993T","-62994G","-62995A","-62996A","-62997C","-62998G","-62999T","-63000A","-63001T","-63002T","-63003A","-63004A","-63005T","-63006A","-63007C","-63008T","-63009T","-63010A","-63011A","-63012T","-63013T","-63014C","-63015T","-63016T","-63017T","-63018T","-63019T","-63020C","-63021A","-63022G","-63023T","-63024G","-63025G","-63026T","-63027A","-63028A","-63029G","-63030A","-63031A","-63032C","-63033C","-63034G","-63035A","-63036T","-63037A","-63038G","-63039G","-63040T","-63041T","-63042A","-63043T","-63044T","-63045G","-63046A","-63047C","-63048A","-63049T","-63050T","-63051G","-63052T","-63053A","-63054T","-63055G","-63056G","-63057T","-63058T","-63059T","-63060T","-63061A","-63062A","-63063A","-63064T","-63065A","-63066T","-63067T","-63068C","-63069T","-63070A","-63071T","-63072A","-63073A","-63074C","-63075T","-63076T","-63077G","-63078A","-63079G","-63080A","-63081C","-63082T","-63083T","-63084G","-63085A","-63086T","-63087A","-63088G","-63089A","-63090T","-63091A","-63092T","-63093T","-63094A","-63095A","-63096T","-63097G","-63098A","-63099C","-63100G","-63101A","-63102A","-63103T","-63104T","-63105G","-63106A","-63107A","-63108A","-63109A","-63110T","-63111T","-63112A","-63113T","-63114T","-63115T","-63116T","-63117T","-63118A","-63119T","-63120C","-63121A","-63122C","-63123C","-63124A","-63125C","-63126G","-63127T","-63128G","-63129T","-63130G","-63131T","-63132T","-63133T","-63134C","-63135A","-63136G","-63137G","-63138A","-63139T","-63140C","-63141A","-63142T","-63143C","-63144G","-63145T","-63146C","-63147G","-63148A","-63149C","-63150G","-63151C","-63152C","-63153A","-63154G","-63155T","-63156T","-63157A","-63158A","-63159C","-63160C","-63161A","-63162A","-63163C","-63164C","-63165G","-63166A","-63167A","-63168T","-63169G","-63170G","-63171A","-63172G","-63173T","-63174A","-63175A","-63176A","-63177A","-63178T","-63179A","-63180A","-63181A","-63182T","-63183A","-63184T","-63185C","-63186A","-63187T","-63188T","-63189A","-63190A","-63191T","-63192A","-63193T","-63194A","-63195T","-63196G","-63197C","-63198T","-63199C","-63200T","-63201A","-63202G","-63203A","-63204T","-63205A","-63206T","-63207T","-63208A","-63209G","-63210T","-63211A","-63212T","-63213T","-63214T","-63215T","-63216T","-63217A","-63218T","-63219T","-63220A","-63221A","-63222T","-63223C","-63224C","-63225T","-63226T","-63227T","-63228G","-63229A","-63230T","-63231T","-63232A","-63233T","-63234C","-63235A","-63236T","-63237C","-63238T","-63239T","-63240C","-63241T","-63242C","-63243G","-63244T","-63245A","-63246C","-63247G","-63248C","-63249G","-63250A","-63251A","-63252T","-63253G","-63254A","-63255T","-63256T","-63257C","-63258C","-63259A","-63260T","-63261G","-63262A","-63263T","-63264C","-63265A","-63266A","-63267G","-63268A","-63269G","-63270T","-63271G","-63272A","-63273T","-63274T","-63275T","-63276G","-63277A","-63278G","-63279A","-63280A","-63281C","-63282A","-63283T","-63284C","-63285C","-63286T","-63287C","-63288C","-63289G","-63290G","-63291A","-63292G","-63293T","-63294A","-63295T","-63296T","-63297A","-63298A","-63299T","-63300G","-63301G","-63302G","-63303T","-63304T","-63305T","-63306A","-63307G","-63308T","-63309A","-63310A","-63311A","-63312C","-63313A","-63314G","-63315T","-63316C","-63317C","-63318A","-63319T","-63320C","-63321G","-63322T","-63323T","-63324G","-63325C","-63326A","-63327A","-63328T","-63329A","-63330A","-63331T","-63332A","-63333A","-63334A","-63335A","-63336G","-63337T","-63338T","-63339G","-63340T","-63341C","-63342C","-63343A","-63344A","-63345G","-63346T","-63347T","-63348A","-63349A","-63350A","-63351G","-63352G","-63353A","-63354T","-63355A","-63356T","-63357T","-63358A","-63359T","-63360G","-63361C","-63362A","-63363T","-63364T","-63365C","-63366G","-63367T","-63368T","-63369T","-63370A","-63371A","-63372A","-63373G","-63374A","-63375T","-63376A","-63377T","-63378C","-63379A","-63380C","-63381C","-63382T","-63383C","-63384A","-63385T","-63386C","-63387T","-63388A","-63389A","-63390C","-63391G","-63392G","-63393A","-63394G","-63395A","-63396C","-63397A","-63398A","-63399T","-63400T","-63401T","-63402T","-63403T","-63404T","-63405G","-63406G","-63407T","-63408A","-63409G","-63410G","-63411T","-63412T","-63413T","-63414T","-63415A","-63416G","-63417A","-63418G","-63419A","-63420C","-63421T","-63422T","-63423T","-63424G","-63425A","-63426A","-63427G","-63428C","-63429T","-63430A","-63431C","-63432T","-63433T","-63434G","-63435T","-63436T","-63437T","-63438A","-63439A","-63440C","-63441A","-63442A","-63443A","-63444G","-63445T","-63446T","-63447A","-63448T","-63449T","-63450C","-63451A","-63452T","-63453C","-63454G","-63455T","-63456C","-63457G","-63458T","-63459C","-63460T","-63461A","-63462C","-63463T","-63464A","-63465T","-63466T","-63467C","-63468T","-63469A","-63470T","-63471T","-63472T","-63473A","-63474A","-63475T","-63476T","-63477T","-63478T","-63479G","-63480T","-63481A","-63482G","-63483T","-63484T","-63485A","-63486A","-63487T","-63488T","-63489T","-63490A","-63491T","-63492C","-63493A","-63494C","-63495A","-63496T","-63497A","-63498T","-63499C","-63500A","-63501C","-63502A","-63503T","-63504T"]}}},{"name":"OQ672579","node_attrs":{"div":67,"accession":"OQ672579","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"lineage":{"value":"B.1"},"strain":{"value":"28022023_anal"},"date":{"value":"2023-02-28"},"strain_display":{"value":"Belgium/OQ672579/2023-02-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A2611-","C2612-","A2613-","C2614-","G2615-","A2616-","T2617-","A2618-","G2619-","A2620-","C2621-","A2622-","T2653-","T2654-","T2655-","A2656-","C2657-","A2658-","C2659-","T2660-","T2661-","T39397C","A48200-","A48201-","T48202-","G48203-","G48204-","A48205-","T48206-","T48207-","T48208-","T48209-","A48210-","T48211-","T48212-","C48213-","G48214-","T48215-","A48216-","G48217-","A48218-","A48219-","A48220-","G48221-","T48222-","A48223-","T48224-","C48225-","T48226-","T48227-","A48228-","T48229-","A48230-","T48231-","A48232-","C48233-","A48234-","C48235-","A48236-","G48237-","T48238-","A48239-","G48240-","A48241-","A48242-","A48243-","A48244-","T48245-","A48246-","A48247-","T48248-","A48249-","T48250-","A48251-","G48252-","A48253-","T48254-","T48255-","T48256-","T48257-","T48258-","T48259-","A48260-","A48261-","A48262-","G48263-","G48264-","A48265-","T48266-","G48267-","A48268-","T48269-","A48270-","C48271-","A48272-","T48273-","T48274-","A48275-","A48276-","G48277-","T48278-","A48279-","A48280-","A48281-","G48282-","T48283-","A48284-","A48285-","A48286-","C48287-","A48288-","A48289-","T48290-","T48291-","T48292-","T48293-","A48294-","C48295-","C48296-","C48297-","T48298-","C48299-","A48300-","A48301-","T48302-","C48303-","A48304-","T48305-","G48306-","T48307-","A48308-","C48309-","T48310-","A48311-","G48312-","C48313-","T48314-","C48315-","T48316-","C48317-","A48318-","A48319-","G48320-","T48321-","A48322-","T48323-","C48324-","T48325-","A48326-","G48327-","T48328-","T48329-","A48330-","G48331-","C48332-","A48333-","A48334-","T48335-","T48336-","T48337-","T48338-","C48339-","C48340-","T48341-","C48342-","A48343-","A48344-","C48345-","A48346-","T48347-","G48348-","T48349-","T48350-","A48351-","T48352-","T48353-","A48354-","C48355-","T48356-","A48357-","A48358-","G48359-","G48360-","A48361-","T48362-","G48363-","T48364-","A48365-","T48366-","T48367-","A48368-","G48369-","C48370-","T48371-","A48372-","A48373-","T48374-","A48375-","C48376-","C48377-","A48378-","A48379-","T48380-","T48381-","T48382-","T48383-","T48384-","T48385-","T48386-","G48387-","T48388-","T48389-","T48390-","T48391-","C48392-","A48393-","T48394-","A48395-","C48396-","A48397-","T48398-","A48399-","T48400-","G48401-","G48402-","T48403-","A48404-","C48405-","G48406-","A48407-","T48408-","G48409-","C48410-","T48411-","G48412-","T48413-","A48414-","A48415-","A48416-","G48417-","T48418-","A48419-","T48420-","A48421-","C48422-","G48423-","A48424-","A48425-","G48426-","C48427-","G48428-","G48429-","T48430-","T48431-","T48432-","T48433-","A48434-","C48435-","G48436-","A48437-","C48438-","A48439-","C48440-","G48441-","C48442-","A48443-","T48444-","T48445-","T48446-","G48447-","A48448-","T48449-","G48450-","C48451-","A48452-","C48453-","C48454-","C48455-","A48456-","C48457-","G48458-","T48459-","T48460-","G48461-","T48462-","A48463-","C48464-","G48465-","T48466-","T48467-","A48468-","A48469-","A48470-","G48471-","C48472-","A48473-","T48474-","T48475-","G48476-","A48477-","C48478-","T48479-","A48480-","A48481-","G48482-","A48483-","A48484-","T48485-","T48486-","A48487-","T48488-","T48489-","T48490-","A48491-","T48492-","C48493-","G48494-","T48495-","T48496-","T48497-","A48498-","G48499-","T48500-","A48501-","A48502-","C48503-","A48504-","C48505-","A48506-","A48507-","T48508-","A48509-","C48510-","A48511-","G48512-","T48513-","C48514-","G48515-","T48516-","A48517-","C48518-","A48519-","A48520-","G48521-","G48522-","A48523-","A48524-","A48525-","G61794-","G61795-","C61796-","A61797-","T61798-","A61815-","G61816-","T61817-","A61818-","C61819-","A61820-","A61821-","G61822-","T61823-","G61824-","G61825-","C61826-","T61827-","G61828-","C61829-","T61830-","A61831-","T61832-","T61833-","T61834-","C61835-","G61836-","G61837-","C61838-","T61839-","G61840-","C61841-","C61842-","A61843-","G61844-","A61845-","G61846-","T61847-","G61848-","T61849-","C61850-","C61851-","A61852-","A61853-","T61854-","T61855-","C61856-","T61857-","A61858-","C61859-","C61860-","G61861-","T61862-","T61863-","G61864-","T61865-","T61866-","A61867-","C61868-","T61869-","C61870-","C61871-","A61872-","T61873-","T61874-","A61875-","T61876-","A61877-","T61878-","A61879-","T61880-","T61881-","C61882-","C61883-","T61884-","T61885-","G61886-","A61887-","A61888-","T61889-","A61890-","A61891-","C61892-","C61893-","T61894-","T61895-","C61896-","A61897-","T61898-","A61899-","G61900-","C61901-","T61902-","A61903-","T61904-","T61905-","T61906-","T61907-","A61908-","A61909-","T61910-","A61911-","G61912-","G61913-","A61914-","T61915-","C61916-","T61917-","A61918-","T61919-","A61920-","T61921-","G61922-","A61923-","T61924-","C61925-","A61926-","G61927-","T61928-","G61929-","T61930-","T61931-","T61932-","A61933-","A61934-","G61935-","C61936-","C61937-","A61938-","T61939-","A61940-","G61941-","C61942-","A61943-","C61944-","A61945-","A61946-","T61947-","T61948-","T61949-","T61950-","C61951-","T61952-","A61953-","A61954-","T61955-","A61956-","C61957-","G61958-","A61959-","G61960-","A61961-","C61962-","G61963-","T61964-","G61965-","A61966-","T61967-","T61968-","T61969-","T61970-","A61971-","T61972-","C61973-","A61974-","A61975-","A61976-","C61977-","A61978-","T61979-","G61980-","A61981-","C61982-","A61983-","T61984-","T61985-","T61986-","T61987-","C61988-","C61989-","T61990-","T61991-","G61992-","T61993-","A61994-","T61995-","C61996-","C61997-","A61998-","T61999-","T62000-","T62001-","C62002-","G62003-","T62004-","T62005-","T62006-","A62007-","A62008-","T62009-","G62010-","A62011-","C62012-","A62013-","A62014-","A62015-","C62016-","A62017-","T62018-","T62019-","T62020-","T62021-","T62022-","G62023-","T62024-","T62025-","G62026-","G62027-","T62028-","G62029-","T62030-","A62031-","A62032-","T62033-","A62034-","A62035-","A62036-","A62037-","A62038-","A62039-","A62040-","A62041-","T62042-","T62043-","A62044-","T62045-","T62046-","T62047-","A62048-","A62049-","T62050-","T62051-","T62052-","T62053-","T62054-","C62055-","A62056-","T62057-","T62058-","A62059-","A62060-","T62061-","A62062-","G62063-","G62064-","G62065-","A62066-","T62067-","T62068-","T62069-","G62070-","A62071-","C62072-","G62073-","T62074-","A62075-","T62076-","G62077-","T62078-","A62079-","G62080-","C62081-","G62082-","T62083-","A62084-","C62085-","A62086-","A62087-","A62088-","A62089-","T62090-","T62091-","A62092-","T62093-","C62094-","G62095-","T62096-","T62097-","C62098-","C62099-","T62100-","G62101-","G62102-","T62103-","A62104-","T62105-","A62106-","T62107-","A62108-","A62152-","A62153-","C62154-","T62155-","T62156-","T62157-","A62158-","A62159-","T62160-","G62161-","A62162-","T62163-","T62164-","G62165-","T62631-","T62632-","T62633-","A62634-","G62635-","G62636-","A62637-","A62638-","T62639-","G62640-","T62641-","A62642-","T62643-","G62644-","G62645-","A62646-","C62647-","T62648-","C62649-","G62650-","C62651-","G62652-","T62653-","T62654-","T62655-","A62656-","G62657-","A62658-","G62659-","G62660-","A62661-","G62662-","T62663-","G62664-","A62665-","A62666-","C62667-","G62668-","T62669-","C62670-","T62671-","T62672-","C62673-","G62674-","G62675-","A62676-","G62677-","T62678-","A62679-","G62680-","T62681-","A62682-","A62683-","A62684-","G62685-","G62686-","A62687-","T62688-","G62689-","A62690-","T62691-","T62692-","C62693-","G62694-","T62695-","C62696-","A62697-","A62698-","A62699-","T62700-","G62701-","A62702-","A63505-","C70785-","G70786-","T70787-","A70788-","T70789-","A70790-","T70829-","C70830-","G70880-","T70881-","G70882-","C70883-","C70884-","G70885-","T70886-","T70887-","A70888-","C70889-","C70890-","C70891-","T70892-","G70893-","C70894-","C70895-","G70907-","C70908-","A70909-","T70910-","T70911-","A70912-","G70913-","A70914-","A70915-","C70916-","C70917-","A70918-","C70919-","G70920-","T70921-","G70940-","A70941-","A70942-","T70963-","T70970-","T70971-","C70972-","G70973-","A70974-","A70975-","A70976-","A70977-","T70978-","A70979-","C70980-","T70981-","A70982-","A70983-","A70984-","T70985-","C70986-","A70987-","T71023-","G71024-","G71025-","A71026-","T71027-","A71028-","T71029-","T71030-","C71031-","T71032-","A71033-","A71034-","C71035-","G71036-","A71037-","A71038-","A71039-","A71040-","C71041-","T71042-","G71043-","T71044-","A71045-","A71046-","C71047-","A71048-","C71049-","C71050-","A71051-","T71052-","A71053-","G71054-","T71055-","G71056-","T71057-","T71058-","C71059-","G71060-","G71061-","C71062-","A71063-","T71064-","C71065-","T71066-","A71067-","T71068-","A71069-","A71070-","G71071-","G71072-","A71073-","T71074-","A71075-","A71076-","T71077-","T71078-","T71079-","A71080-","C71081-","T71082-","A71083-","C71084-","T71085-","G71086-","A71087-","G71088-","T71089-","A71090-","T71091-","A71092-","A71129-","C71130-","C71131-","A71132-","A71133-","T71134-","A71135-","C71136-","T71137-","A71138-","A71139-","A71140-","A71141-","G71142-","T71143-","G71144-","A71145-","T71146-","A71147-","A71148-","T71149-","A71150-","T71172-","T71173-","A71174-","A71175-","A71176-","A71177-","A71178-","A71179-","T71180-","G71181-","G71182-","T71183-","G71184-","T71185-","T71186-","C71187-","C71188-","A71189-","G71190-","C71191-","T71192-","C71193-","G71194-","T71195-","G71196-","T71197-","G71198-","T71199-","T71200-","C71201-","T71202-","A71203-","C71204-","A71205-","T71206-","G71207-","C71208-","G71209-","G71210-","C71211-","A71212-","A71213-","A71214-","G71215-","A71216-","T71217-","A71218-","T71219-","T71220-","T71221-","C71222-","T71223-","C71224-","A71225-","C71226-","G71227-","A71228-","A71229-","C71230-","G71231-","A71232-","T71233-","A71234-","T71235-","A71236-","A71237-","A71238-","T71239-","T71240-","G71241-","A71242-","T71243-","T71244-","A71245-","T71246-","A71247-","C71248-","G71249-","A71250-","A71251-","A71252-","A71253-","A71254-","A71255-","A71256-","T71257-","C71258-","A71259-","T71260-","T71261-","A71262-","A71263-","A71264-","G71265-","G71266-","A71267-","T71268-","G71269-","T71270-","A71271-","C71272-","T71273-","A71274-","G71275-","T71276-","C71277-","A71278-","G71279-","T71280-","G71281-","T71282-","A71283-","A71284-","A71285-","G71286-","A71287-","A71288-","C71289-","G71290-","A71291-","A71292-","T71293-","G71294-","T71295-","T71296-","G71297-","T71298-","A71299-","G71300-","G71301-","T71302-","T71303-","A71304-","A71305-","A71306-","A71307-","T71308-","T71309-","A71310-","T71311-","C71312-","T71313-","A71314-","C71315-","A71316-","C71317-","A71318-","A71319-","A71320-","T71321-","A71322-","G71323-","A71324-","A71325-","C71326-","C71327-","T71328-","C71329-","A71330-","A71331-","C71332-","G71333-","T71334-","A71335-","A71336-","C71337-","T71338-","T71339-","A71340-","A71341-","C71342-","A71343-","G71344-","T71345-","G71346-","C71347-","A71348-","A71349-","C71350-","C71351-","T71352-","C71353-","T71354-","A71355-","T71356-","T71357-","G71358-","G71359-","A71360-","T71361-","A71362-","T71363-","A71364-","A71365-","A71366-","C71367-","T71368-","A71369-","A71370-","T71371-","G71372-","G71373-","A71374-","T71375-","C71376-","C71377-","G71378-","G71379-","T71380-","T71381-","A71382-","A71383-","T71384-","T71385-","T71386-","T71387-","A71388-","T71389-","C71390-","A71391-","A71392-","G71393-","A71394-","C71395-","A71396-","T71397-","A71398-","T71399-","G71400-","C71401-","G71402-","C71403-","C71404-","T71405-","A71406-","G71407-","A71408-","G71409-","G71410-","T71411-","T71412-","C71413-","T71414-","A71415-","T71416-","T71417-","A71418-","T71419-","T71420-","T71421-","T71422-","T71423-","A71424-","T71425-","T71426-","G71517-","T71518-","A71519-","G71520-","T71521-","T71522-","G71523-","A71524-","A71525-","T71526-","C71527-","T71528-","A71529-","C71530-","C71531-","T71532-","A71533-","T71534-","A71535-","G71536-","A71537-","A71538-","A71539-","A71540-","G71541-","G71542-","A71543-","G71544-","T71545-","T71546-","A71547-","G71548-","A71549-","A71550-","T71551-","A71552-","G71553-","T71554-","C71555-","C71556-","C71557-","A71558-","T71559-","T71560-","G71561-","G71562-","A71563-","T71564-","A71565-","G71566-","A71567-","T71568-","T71569-","T71570-","T71571-","T71572-","T71573-","G71574-","A71575-","A71576-","G71577-","G71578-","A71579-","T71580-","A71581-","T71582-","C71583-","T71584-","T71585-","A71586-","G71587-","T71588-","G71589-","C71590-","A71591-","A71592-","A71593-","A71594-","G71595-","T71596-","A71597-","T71598-","A71599-","C71600-","A71601-","T71602-","G71603-","T71604-","T71605-","A71606-","G71607-","A71608-","G71609-","A71610-","A71611-","T71612-","A71613-","T71614-","T71615-","C71616-","A71617-","A71618-","G71619-","T71620-","T71621-","A71622-","T71623-","G71624-","A71625-","A71626-","A71627-","A71628-","T71629-","A71630-","G71631-","C71632-","A71633-","G71634-","C71635-","T71636-","G71637-","A71638-","T71639-","A71640-","T71641-","G71642-","T71643-","C71644-","G71645-","T71646-","T71647-","A71648-","A71649-","C71650-","T71651-","T71652-","G71676-","G71677-","T71678-","C71679-","G71709-","C71710-","T71711-","G71712-","A71713-","A71714-","T71715-","G71716-","T71717-","T71718-","A71719-","T71720-","A71721-","A71722-","A71723-","A71724-","A71725-","T71726-","G71727-","C71728-","C71729-","G71730-","G71731-","T71732-","A71733-","T71734-","T71735-","G71736-","A71737-","T71738-","A71739-","C71740-","A71741-","T71742-","C71743-","G71744-","T71745-","C71746-","T71747-","A71748-","A71749-","A71750-","C71751-","G71752-","A71753-","A71754-","T71755-","A71756-","T71757-","T71758-","A71759-","G71760-","G71761-","T71762-","A71763-","A71764-","A71765-","G71766-","A71767-","T71768-","A71769-","T71770-","T71771-","T71772-","T71773-","T71774-","C71775-","T71776-","G71777-","A71778-","G71779-","C71780-","C71781-","A71782-","A71783-","A71784-","A71785-","C71786-","T71787-","T71788-","T71789-","A71790-","C71791-","A71792-","G71793-","A71794-","T71795-","G71796-","A71797-","T71798-","A71799-","A71800-","T71801-","A71802-","G71803-","A71804-","T71805-","G71806-","G71807-","A71808-","T71809-","A71810-","A71811-","A71812-","G71813-","C71856-","C71910-","T71911-","T71912-","T71913-","T71914-","T71915-","C71916-","T71917-","T71918-","A71919-","A71920-","C71921-","G71922-","T71923-","T71924-","G71925-","T71926-","T71927-","T71928-","G71929-","C71930-","C71931-","A71932-","T71933-","C71934-","A71935-","C71936-","T71937-","C71938-","T71939-","C71940-","A71941-","T71942-","A71943-","A71944-","T71945-","G71946-","T71947-","A71948-","A71949-","A71950-","G71951-","A71952-","T71953-","A71954-","T71955-","T71956-","C71957-","T71958-","A71959-","A71960-","A71961-","A71962-","T71963-","G71964-","G71965-","T71966-","A71967-","A71968-","A71969-","C71970-","T71971-","T71972-","T71973-","T71974-","G71975-","C71976-","A71977-","T71978-","A71979-","T71980-","C71981-","G71982-","G71983-","A71984-","T71985-","G71986-","C71987-","A71988-","G71989-","A71990-","A71991-","A71992-","T71993-","T71994-","G71995-","G71996-","T71997-","A71998-","T71999-","A72000-","A72001-","A72002-","T72003-","G72004-","T72005-","T72006-","G72007-","T72008-","A72009-","A72010-","T72011-","T72012-","G72013-","T72014-","A72015-","T72016-","T72017-","A72018-","T72019-","T72020-","T72021-","C72022-","C72023-","C72024-","G72025-","T72026-","C72027-","A72028-","A72029-","T72030-","G72031-","G72032-","A72033-","C72034-","T72035-","A72036-","G72037-","T72038-","C72039-","A72040-","C72041-","A72042-","G72043-","C72044-","T72045-","C72046-","C72047-","A72048-","T72049-","C72050-","A72051-","G72052-","T72053-","T72054-","T72055-","T72056-","A72057-","T72058-","A72059-","T72060-","C72061-","C72062-","T72063-","T72064-","T72065-","A72066-","G72067-","A72068-","G72069-","T72070-","A72071-","T72072-","T72073-","T72074-","C72075-","T72076-","C72077-","A72078-","C72079-","T72080-","C72081-","G72082-","T72083-","G72084-","T72085-","C72086-","T72087-","A72088-","G72089-","C72090-","A72091-","T72092-","T72093-","C72094-","T72095-","A72096-","G72097-","A72098-","G72099-","C72100-","A72101-","T72102-","T72103-","C72104-","C72105-","A72106-","T72107-","G72108-","A72109-","T72110-","C72111-","T72112-","G72113-","T72114-","T72115-","T72116-","A72117-","T72118-","C72119-","G72120-","T72121-","T72122-","G72123-","A72124-","T72125-","A72126-","T72127-","T72128-","G72129-","G72130-","C72131-","C72132-","G72133-","G72134-","A72135-","A72136-","A72137-","G72138-","A72139-","T72140-","A72141-","G72142-","A72143-","T72144-","T72145-","T72146-","T72147-","T72148-","T72149-","A72150-","T72151-","T72152-","T72153-","T72154-","T72155-","T72156-","A72157-","T72158-","T72159-","A72160-","T72161-","A72162-","T72163-","T72164-","A72165-","C72166-","T72167-","A72168-","T72169-","T72170-","G72171-","G72172-","C72173-","A72174-","A72175-","T72176-","T72177-","G72178-","T72179-","A72180-","G72181-","A72182-","T72183-","A72184-","T72185-","A72186-","A72187-","C72188-","T72189-","T72190-","C72191-","T72192-","G72193-","G72194-","T72195-","A72196-","A72197-","A72198-","T72199-","A72200-","T72201-","T72202-","T72203-","T72204-","T72205-","C72206-","T72207-","A72208-","C72209-","C72210-","T72211-","T72212-","T72213-","T72214-","C72215-","A72216-","A72217-","T72218-","C72219-","T72220-","C72221-","T72222-","T72223-","C72224-","T72225-","A72226-","T72227-","T72228-","T72229-","T72230-","C72231-","A72232-","A72233-","G72234-","C72235-","C72236-","G72237-","G72238-","C72239-","T72240-","A72241-","T72242-","A72243-","T72244-","A72245-","T72246-","T72247-","C72248-","T72249-","G72250-","C72251-","T72252-","A72253-","T72254-","A72255-","T72256-","T72257-","G72258-","T72259-","T72260-","A72261-","C72262-","T72263-","A72264-","G72265-","T72266-","A72267-","T72268-","C72269-","A72270-","A72271-","T72272-","A72273-","C72274-","C72275-","T72276-","T72277-","T72278-","T72279-","C72280-","T72281-","G72282-","G72283-","C72284-","T72285-","A72286-","A72287-","G72288-","A72289-","A72290-","G72291-","T72292-","C72293-","A72294-","T72295-","A72296-","T72297-","G72298-","T72299-","G72300-","G72301-","T72302-","A72303-","T72304-","T72305-","C72306-","A72307-","C72308-","T72309-","A72310-","T72311-","A72312-","T72313-","C72314-","A72315-","G72316-","T72317-","T72318-","T72319-","T72320-","A72321-","A72322-","C72323-","T72324-","G72325-","G72326-","T72327-","A72328-","G72329-","T72330-","T72331-","C72332-","C72333-","A72334-","T72335-","T72336-","A72337-","G72338-","C72339-","C72340-","T72341-","T72342-","T72343-","C72344-","C72345-","A72346-","C72347-","T72348-","T72349-","C72350-","T72351-","G72352-","C72353-","A72354-","G72355-","A72356-","A72357-","T72358-","A72359-","A72360-","T72361-","T72362-","A72363-","G72364-","A72365-","A72366-","A72367-","T72368-","T72369-","G72370-","G72371-","T72372-","T72373-","C72374-","T72375-","T72376-","T72377-","A72378-","C72379-","C72380-","A72381-","G72382-","A72383-","A72384-","A72385-","A72386-","T72387-","C72388-","C72389-","A72390-","G72391-","C72392-","T72393-","A72394-","A89103-","A89104-","A89105-","G89148-","T89149-","C89150-","A89151-","T89166-","C89229-","A89230-","G89231-","T89232-","G89233-","T89234-","T89235-","A89373-","C89374-","T89375-","T89376-","A89377-","T89378-","A89379-","T89380-","T89381-","C89382-","G89383-","T89384-","G89385-","T89386-","C89387-","T89388-","A89389-","G89390-","T89391-","A89392-","G89393-","A89394-","T89700-","C151552T","C167451T","-194549A","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","C194595-","G194596-","T194597-","G194598-","T194599-"],"OPG002":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-"],"OPG002_dup":["C44-","L45-","S46-","C47-"],"OPG057":["N267D"],"OPG080":["A75-"],"OPG089":["S307F","I309-","P310-","S322-","V339-","P340-","L341-","P342-","C343-","Q344-","L349-","E350-","P351-","R352-","K353-","E359-"],"OPG091":["L163-"],"OPG092":["A186-","G187-","F188-","S189-","G190-","K191-","E192-","P193-","I194-","S195-","N196-","Y197-","S198-","A199-","E200-","V201-","E202-","R203-","L204-","M205-","E206-","L207-","P208-","V209-","K210-","T211-","D212-","I213-","V214-","N215-","T216-","T217-","Y218-","D219-","F220-","L221-","A222-","R223-","K224-","G225-","I226-","D227-","T228-","S229-","N230-","N231-","I232-","A233-","E234-","Y235-","I236-","A237-","G238-","L239-","K240-","I241-","E242-","E243-","I244-","E245-","K246-","V247-","E248-","K249-","Y250-","L251-","P252-","E253-","V254-","I255-","S256-","T257-","I258-","A259-","N260-","S261-","N262-","I263-","I264-","K265-","N266-","K267-","K268-","S269-","I270-","F271-","P272-","A273-","N274-","I275-","N276-","D277-","K278-","Q279-","I280-","M281-","E282-","C283-","S284-","R285-","M286-","L287-","D288-","T289-","S290-","E291-","K292-","Y293-","S294-","K295-","G296-","Y297-","K298-","T299-","D300-","G301-","A302-","V303-","T304-","S305-","P306-","L307-","T308-","G309-","N310-","N311-","T312-","I313-","T314-","T315-","F316-","I317-","P318-","I319-","S320-","A321-","S322-","D323-","M324-","Q325-","K326-","F327-","T328-","I329-","L330-","E331-","Y332-","L333-","Y334-","I335-","M336-","R337-","V338-","M339-","A340-","N341-","N342-","V343-","K344-","K345-","K346-","V365-"],"OPG109":["L19-","L20-","D21-","T22-","N23-","I24-","S25-","D100-"],"OPG178":["S15F"]},"labels":{"aa":"OPG002: K31-, C32-, K33-, D34-, N35-, E36-, Y37-; OPG002_dup: C44-, L45-, S46-, C47-; OPG057: N267D; OPG080: A75-; OPG089: S307F, I309-, P310-, S322-, V339-, P340-, L341-, P342-, C343-, Q344-, L349-, E350-, P351-, R352-, K353-, E359-; OPG091: L163-; OPG092: A186-, G187-, F188-, S189-, G190-, K191-, E192-, P193-, I194-, S195-, N196-, Y197-, S198-, A199-, E200-, V201-, E202-, R203-, L204-, M205-, E206-, L207-, P208-, V209-, K210-, T211-, D212-, I213-, V214-, N215-, T216-, T217-, Y218-, D219-, F220-, L221-, A222-, R223-, K224-, G225-, I226-, D227-, T228-, S229-, N230-, N231-, I232-, A233-, E234-, Y235-, I236-, A237-, G238-, L239-, K240-, I241-, E242-, E243-, I244-, E245-, K246-, V247-, E248-, K249-, Y250-, L251-, P252-, E253-, V254-, I255-, S256-, T257-, I258-, A259-, N260-, S261-, N262-, I263-, I264-, K265-, N266-, K267-, K268-, S269-, I270-, F271-, P272-, A273-, N274-, I275-, N276-, D277-, K278-, Q279-, I280-, M281-, E282-, C283-, S284-, R285-, M286-, L287-, D288-, T289-, S290-, E291-, K292-, Y293-, S294-, K295-, G296-, Y297-, K298-, T299-, D300-, G301-, A302-, V303-, T304-, S305-, P306-, L307-, T308-, G309-, N310-, N311-, T312-, I313-, T314-, T315-, F316-, I317-, P318-, I319-, S320-, A321-, S322-, D323-, M324-, Q325-, K326-, F327-, T328-, I329-, L330-, E331-, Y332-, L333-, Y334-, I335-, M336-, R337-, V338-, M339-, A340-, N341-, N342-, V343-, K344-, K345-, K346-, V365-; OPG109: L19-, L20-, D21-, T22-, N23-, I24-, S25-, D100-; OPG178: S15F"}}}]}]},{"name":"NODE_0000046","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C18441T","G22415A","G70002A","C132698T","G143951A","C148604T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G154188A","T179078-","A179079-","T179080-","A179081-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C196745-","C196746-","A196747-"],"OPG031":["E130K"],"OPG089":["R46K"],"OPG165":["D146N"],"OPG174":["M264I"]},"labels":{"aa":"OPG031: E130K; OPG089: R46K; OPG165: D146N; OPG174: M264I"}},"children":[{"name":"OR499993","node_attrs":{"div":68,"accession":"OR499993","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00537/2023"},"date":{"value":"2023-07-06"},"strain_display":{"value":"USA/OR499993/2023-07-06"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179082-","C179091-","C179100-","C179109-","C179118-","C179127-","C179136-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000047","node_attrs":{"div":69,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C14823A","-179078T","-179079A","-179080T","-179081A","-179083A","-179084T","-179085T","-179086A","-179087T","-179088A","-179089T","-179090A","-179092A","-179093T","-179094T","-179095A","-179096T","-179097A","-179098T","-179099A","-179101A","-179102T","-179103T","-179104A","-179105T","-179106A","-179107T","-179108A","-179110A","-179111T","-179112T","-179113A","-179114T","-179115A","-179116T","-179117A","-179119A","-179120T","-179121T","-179122A","-179123T","-179124A","-179125T","-179126A","-179128A","-179129T","-179130T","-179131A","-179132T","-179133A","-179134T","-179135A","-179137A","-179138T","-179139T","-179140A","-179141T","-179142A","-179143T","-179144A"],"OPG025":["D149Y"]},"labels":{"aa":"OPG025: D149Y"}},"children":[{"name":"OR643702","node_attrs":{"div":69,"accession":"OR643702","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00560/2023"},"date":{"value":"2023-08-08"},"strain_display":{"value":"USA/OR643702/2023-08-08"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OR499982","node_attrs":{"div":69,"accession":"OR499982","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00525/2023"},"date":{"value":"2023-06-14"},"strain_display":{"value":"USA/OR499982/2023-06-14"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000048","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T606-","C118453T","G137276A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177009A","T178873C","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","A196614-"],"OPG136":["E379K"],"OPG153":["S131F"],"OPG205":["E452K"]},"labels":{"aa":"OPG136: E379K; OPG153: S131F; OPG205: E452K"}},"children":[{"name":"OR499971","node_attrs":{"div":67,"accession":"OR499971","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00514/2023"},"date":{"value":"2023-05-04"},"strain_display":{"value":"USA/OR499971/2023-05-04"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T39397C","C117119T"],"OPG057":["N267D"]},"labels":{"aa":"OPG057: N267D"}}},{"name":"NODE_0000049","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G635-","A636-","A637-","A1697-","G39327A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","T195519-"],"OPG057":["A290V"]},"labels":{"aa":"OPG057: A290V"}},"children":[{"name":"OR499948","node_attrs":{"div":66,"accession":"OR499948","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00491/2023"},"date":{"value":"2023-04-10"},"strain_display":{"value":"USA/OR499948/2023-04-10"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OR499967","node_attrs":{"div":66,"accession":"OR499967","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00510/2023"},"date":{"value":"2023-05-04"},"strain_display":{"value":"USA/OR499967/2023-05-04"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A672-","C673-","A674-","T196633-","C196634-","T196635-"]}}}]}]},{"name":"NODE_0000052","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.16"}},"branch_attrs":{"mutations":{"nuc":["C9389T","C30154T","G161797A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A185557C","T196852-","T196854-"],"OPG188":["E68K"],"OPG210":["K1401T"]},"labels":{"aa":"OPG188: E68K; OPG210: K1401T","clade":"B.1.16"}},"children":[{"name":"OP642383","node_attrs":{"div":67,"accession":"OP642383","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.16"},"strain":{"value":"ANT-LDSP-ANT-MPX-24909-C"},"date":{"value":"2022-09-09"},"strain_display":{"value":"Colombia/OP642383/2022-09-09"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G6863A","C132608T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP693653","node_attrs":{"div":66,"accession":"OP693653","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.16"},"strain":{"value":"DC_INS_MPX_0719_L"},"date":{"value":"2022-08-29"},"strain_display":{"value":"Colombia/OP693653/2022-08-29"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G121275A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG139":["P32S"]},"labels":{"aa":"OPG139: P32S"}}},{"name":"OP693647","node_attrs":{"div":65,"accession":"OP693647","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.16"},"strain":{"value":"DC_INS_MPX_0082_L"},"date":{"value":"2022-08-08"},"strain_display":{"value":"Colombia/OP693647/2022-08-08"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A1701-","C1702-","T1703-","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-","G196853-"]}}},{"name":"OQ197862","node_attrs":{"div":66,"accession":"OQ197862","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Rosales,A.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Rosales,A.,Mercado-Reyes,M.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.16"},"strain":{"value":"DC_INS_MPX-1119-H"},"date":{"value":"2022-10-24"},"strain_display":{"value":"Colombia/OQ197862/2022-10-24"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","G23118A","T197076-","T197077-","C197078-"]}}},{"name":"OQ696097","node_attrs":{"div":67,"accession":"OQ696097","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.16"},"strain":{"value":"ANT-LDSP-ANT-MPX-30512O"},"date":{"value":"2022-11-10"},"strain_display":{"value":"Colombia/OQ696097/2022-11-10"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G23673A","G37974A","-196852T","-196854T"],"OPG039":["S149L"],"OPG056":["S354L"]},"labels":{"aa":"OPG039: S149L; OPG056: S354L"}}}]},{"name":"NODE_0000060","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{"nuc":["T606-","G181367A","A196614-"]},"labels":{"clade":"B.1.9"}},"children":[{"name":"ON843175","node_attrs":{"div":62,"accession":"ON843175","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0043/2022"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Portugal/ON843175/2022-05-30"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP693652","node_attrs":{"div":63,"accession":"OP693652","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.9"},"strain":{"value":"DC_INS_MPX_0718_L"},"date":{"value":"2022-08-16"},"strain_display":{"value":"Colombia/OP693652/2022-08-16"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-606T","G134122T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP687938","node_attrs":{"div":65,"accession":"OP687938","author":{"author":"Gigante,C.M.,Acheampong,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Morrison,S.S.,Seabolt,M.H.,Weigand,M.R.,Knipe,K.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,McDermott,D.,Li,Y.","value":"Gigante,C.M.,Acheampong,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Morrison,S.S.,Seabolt,M.H.,Weigand,M.R.,Knipe,K.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,McDermott,D.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.9"},"strain":{"value":"MPXV_USA_2022_NJ0005"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP687938/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G61329A","C101868T","C103427T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG121":["P27S"]},"labels":{"aa":"OPG121: P27S"}}},{"name":"NODE_0000061","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{"nuc":["G176823A"],"OPG205":["E390K"]},"labels":{"aa":"OPG205: E390K"}},"children":[{"name":"ON880538","node_attrs":{"div":64,"accession":"ON880538","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.9"},"strain":{"value":"MpxV/human/CAN/UN-NML-3336/2022"},"date":{"value":"2022-06-01"},"strain_display":{"value":"Canada/ON880538/2022-06-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C32627T"]}}},{"name":"NODE_0000062","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{"nuc":["-606T","A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","C57110T","-196614A"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG074":["E6K"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG074: E6K"}},"children":[{"name":"ON649713","node_attrs":{"div":64,"accession":"ON649713","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0020/2022"},"date":{"value":"2022-05-19"},"strain_display":{"value":"Portugal/ON649713/2022-05-19"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP555485","node_attrs":{"div":65,"accession":"OP555485","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0389/2022"},"date":{"value":"2022-07-12"},"strain_display":{"value":"Portugal/OP555485/2022-07-12"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159148A"],"OPG185":["D78N"]},"labels":{"aa":"OPG185: D78N"}}}]},{"name":"NODE_0000063","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{"nuc":["C34432T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155157A"],"OPG053":["E87K"],"OPG181":["R249K"]},"labels":{"aa":"OPG053: E87K; OPG181: R249K"}},"children":[{"name":"OP324505","node_attrs":{"div":66,"accession":"OP324505","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0191/2022"},"date":{"value":"2022-06-28"},"strain_display":{"value":"Portugal/OP324505/2022-06-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-606T","-607T","G4195A","C193015T"],"OPG003":["S138L"],"OPG003_dup":["S138L"]},"labels":{"aa":"OPG003: S138L; OPG003_dup: S138L"}}},{"name":"OP555563","node_attrs":{"div":65,"accession":"OP555563","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0487/2022"},"date":{"value":"2022-08-11"},"strain_display":{"value":"Portugal/OP555563/2022-08-11"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000064","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.17"}},"branch_attrs":{"mutations":{"nuc":["G12169A","G44960A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]},"labels":{"clade":"B.1.17"}},"children":[{"name":"OP442552","node_attrs":{"div":63,"accession":"OP442552","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.17"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00085/2022"},"date":{"value":"2022-07-13"},"strain_display":{"value":"USA/OP442552/2022-07-13"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G771-","T772-","G773-","A196789-","A196790-","T196791-"]}}},{"name":"OP392544","node_attrs":{"div":66,"accession":"OP392544","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.17"},"strain":{"value":"MpxV/human/USA/WA-UW-083781/2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP392544/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A11836G","C113363T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G171959A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG132":["D60N"]},"labels":{"aa":"OPG132: D60N"}}},{"name":"OP748959","node_attrs":{"div":64,"accession":"OP748959","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.17"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00273/2022"},"date":{"value":"2022-07-14"},"strain_display":{"value":"USA/OP748959/2022-07-14"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T658-","A659-","T660-","A11160G"],"OPG023":["F581L"]},"labels":{"aa":"OPG023: F581L"}}},{"name":"OQ054244","node_attrs":{"div":63,"accession":"OQ054244","author":{"author":"Gigante,C.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y.","value":"Gigante,C.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.17"},"strain":{"value":"MPXV_USA_2022_CA0029"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ054244/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A173316-","T173317-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP890565","node_attrs":{"div":64,"accession":"OP890565","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.17"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00308/2022"},"date":{"value":"2022-11-09"},"strain_display":{"value":"USA/OP890565/2022-11-09"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A763-","A764-","T765-","C39334G","T196627-","C196628-","T196629-"],"OPG057":["A288P"]},"labels":{"aa":"OPG057: A288P"}}},{"name":"OQ888843","node_attrs":{"div":66,"accession":"OQ888843","author":{"author":"Hemarajata,P.,Garrigues,J.M.,Green,N.M.","value":"Hemarajata,P.,Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.17"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00483/2022"},"date":{"value":"2022-10-13"},"strain_display":{"value":"USA/OQ888843/2022-10-13"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T39397C","G86148A","C177626T"],"OPG057":["N267D"]},"labels":{"aa":"OPG057: N267D"}}},{"name":"NODE_0000065","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.17"}},"branch_attrs":{"mutations":{"nuc":["A39395-","T39396-","T39397-","C85931T"],"OPG057":["N267-"]},"labels":{"aa":"OPG057: N267-"}},"children":[{"name":"OQ330999","node_attrs":{"div":65,"accession":"OQ330999","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.17"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00391/2022"},"date":{"value":"2022-12-19"},"strain_display":{"value":"USA/OQ330999/2022-12-19"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C174129T"]}}},{"name":"OQ503830","node_attrs":{"div":68,"accession":"OQ503830","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.17"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00407/2023"},"date":{"value":"2023-01-10"},"strain_display":{"value":"USA/OQ503830/2023-01-10"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C49265T","G71249A","G79741A","G182189A"],"OPG090":["R24Q"],"OPG102":["M219I"]},"labels":{"aa":"OPG090: R24Q; OPG102: M219I"}}}]}]},{"name":"NODE_0000066","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C141757T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A"]}},"children":[{"name":"OR126131","node_attrs":{"div":66,"accession":"OR126131","author":{"author":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C.","value":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Spain"},"clade_membership":{"value":"IIb"},"institution":{"value":"Hospital Ramon y Cajal, Microbiology"},"lineage":{"value":"B.1"},"strain":{"value":"HRYC_MPXV001"},"date":{"value":"2022-09-21"},"strain_display":{"value":"Spain/OR126131/2022-09-21"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C11749-","C34432T","C48324T","G101294A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G190695A"],"OPG016":["E96K"],"OPG053":["E87K"],"OPG120":["S152L"]},"labels":{"aa":"OPG016: E96K; OPG053: E87K; OPG120: S152L"}}},{"name":"NODE_0000067","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.18"}},"branch_attrs":{"mutations":{"nuc":["C43706T","T124690C"]},"labels":{"clade":"B.1.18"}},"children":[{"name":"OP628451","node_attrs":{"div":64,"accession":"OP628451","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.18"},"strain":{"value":"MpxV/human/USA/WA-UW-083401/2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP628451/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP615266","node_attrs":{"div":69,"accession":"OP615266","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.18"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00193/2022"},"date":{"value":"2022-07-19"},"strain_display":{"value":"USA/OP615266/2022-07-19"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G24063A","G54088A","G59082A","A140155T","C145187T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C190067T","G191268A"],"OPG015_dup":["R72K"],"OPG039":["S19F"],"OPG167":["R74K"]},"labels":{"aa":"OPG015_dup: R72K; OPG039: S19F; OPG167: R74K"}}},{"name":"OQ330978","node_attrs":{"div":65,"accession":"OQ330978","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.18"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00375/2022"},"date":{"value":"2022-10-06"},"strain_display":{"value":"USA/OQ330978/2022-10-06"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A185923C","A196614-"],"OPG210":["K1523T"]},"labels":{"aa":"OPG210: K1523T"}}},{"name":"OQ721920","node_attrs":{"div":66,"accession":"OQ721920","author":{"author":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.18"},"strain":{"value":"MPXV_USA_2022_IL0009"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721920/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","G78759A","C126911T","A196614-"],"OPG101":["E92K"],"OPG148":["S309F"]},"labels":{"aa":"OPG101: E92K; OPG148: S309F"}}},{"name":"NODE_0000068","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.18"}},"branch_attrs":{"mutations":{"nuc":["C170049T"]}},"children":[{"name":"OR464199","node_attrs":{"div":70,"accession":"OR464199","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.18"},"strain":{"value":"MPXV_USA_2022_NY0051"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OR464199/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C45127T","G91787A","G91880A","G105147A","C114521T"],"OPG064":["E258K"],"OPG133":["M392I"]},"labels":{"aa":"OPG064: E258K; OPG133: M392I"}}},{"name":"NODE_0000069","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.18"}},"branch_attrs":{"mutations":{"nuc":["G67758A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP837471","node_attrs":{"div":66,"accession":"OP837471","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.18"},"strain":{"value":"VAC_INS_MPX_1052_E"},"date":{"value":"2022-10-25"},"strain_display":{"value":"Colombia/OP837471/2022-10-25"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OQ148474","node_attrs":{"div":70,"accession":"OQ148474","author":{"author":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"lineage":{"value":"B.1.18"},"strain":{"value":"LBMB-UTP_MP-025_VAC"},"date":{"value":"2022-11-15"},"strain_display":{"value":"Colombia/OQ148474/2022-11-15"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C128242T","G144572A","C166940T","C168829T"],"OPG150":["S155F"],"OPG166":["A59T"]},"labels":{"aa":"OPG150: S155F; OPG166: A59T"}}}]}]}]}]},{"name":"NODE_0000070","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.15"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","G149818A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G151362A"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG176":["D4N"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG176: D4N","clade":"B.1.15"}},"children":[{"name":"ON694335","node_attrs":{"div":63,"accession":"ON694335","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/Germany/2022/RKI018"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/ON694335/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-","A196614-"]}}},{"name":"OP324453","node_attrs":{"div":64,"accession":"OP324453","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.15"},"strain":{"value":"Monkeypox/PT0129/2022"},"date":{"value":"2022-07-12"},"strain_display":{"value":"Portugal/OP324453/2022-07-12"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","C18133T","-196615A","-196616T"]}}},{"name":"OP484673","node_attrs":{"div":66,"accession":"OP484673","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/Germany/2022/RKI352"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP484673/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C21128T","G74187T","C151111T"],"OPG037":["E436K"],"OPG094":["Q136H"]},"labels":{"aa":"OPG037: E436K; OPG094: Q136H"}}},{"name":"OP764619","node_attrs":{"div":63,"accession":"OP764619","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/Germany/2022/RKI561"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OP764619/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000071","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.15"}},"branch_attrs":{"mutations":{"nuc":["C8385T","-11326A","-11327T","-11328C","-11329T","-11330A","-11331C","-11332G","-11333A","-11334T","-11335A","-11336T","-11337T","-11338A","-11339G","-11340A","-11341T","-11342A","-11343C","-11344T","-11345T","-11346C","-11347A","-11348C","-11349T","-11350C","-11351A","-11352A","-11353T","-11354G","-11355A","-11356A","-11357T","-11358C","-11359A","-11360A","-11361T","-11362C","-11363A","-11364C","-11365A","-11366C","-11367A","-11368A","-11369T","-11370C","-11371T","-11372A","-11373A","-11374T","-11375G","-11376T","-11377A","-11378G","-11379G","-11380T","-11381T","-11382T","-11383A","-11384T","-11385G","-11386A","-11387C","-11388A","-11389T","-11390A","-11391A","-11392T","-11393A","-11394G","-11395C","-11396A","-11397T","-11398T","-11399T","-11400T","-11401C","-11402A","-11403G","-11404C","-11405A","-11406G","-11407T","-11408T","-11409C","-11410A","-11411A","-11412T","-11413G","-11414T","-11415T","-11416T","-11417C","-11418T","-11419A","-11420G","-11421A","-11422T","-11423T","-11424C","-11425G","-11426T","-11427T","-11428G","-11429A","-11430T","-11431G","-11432G","-11433C","-11434A","-11435A","-11436T","-11437G","-11438G","-11439T","-11440T","-11441A","-11442T","-11443A","-11444C","-11445A","-11446T","-11447G","-11448T","-11449A","-11450T","-11451A","-11452T","-11453C","-11454C","-11455G","-11456T","-11457T","-11458A","-11459T","-11460T","-11461T","-11462G","-11463A","-11464T","-11465C","-11466T","-11467A","-11468A","-11469T","-11470G","-11471T","-11472T","-11473G","-11474A","-11475C","-11476A","-11477T","-11478C","-11479T","-11480G","-11481A","-11482A","-11483C","-11484C","-11485G","-11486G","-11487A","-11488T","-11489T","-11490C","-11491T","-11492A","-11493G","-11494C","-11495A","-11496G","-11497T","-11498A","-11499A","-11500A","-11501G","-11502A","-11503T","-11504A","-11505C","-11506T","-11507A","-11508G","-11509A","-11510G","-11511A","-11512T","-11513T","-11514G","-11515T","-11516T","-11517T","-11518A","-11519T","-11520T","-11521A","-11522T","-11523A","-11524T","-11525C","-11526T","-11527A","-11528A","-11529C","-11530A","-11531G","-11532C","-11533C","-11534T","-11535T","-11536G","-11537T","-11538G","-11539A","-11540A","-11541G","-11542A","-11543A","-11544G","-11545T","-11546G","-11547T","-11548T","-11549T","-11550C","-11551T","-11552C","-11553C","-11554T","-11555C","-11556G","-11557T","-11558T","-11559T","-11560G","-11561T","-11562C","-11563A","-11564A","-11565T","-11566C","-11567A","-11568T","-11569G","-11570T","-11571T","-11572A","-11573A","-11574T","-11575G","-11576T","-11577C","-11578T","-11579T","-11580T","-11581A","-11582A","-11583G","-11584A","-11585T","-11586A","-11587A","-11588G","-11589G","-11590T","-11591A","-11592G","-11593A","-11594C","-11595A","-11596A","-11597A","-11598T","-11599G","-11600T","-11601T","-11602T","-11603A","-11604T","-11605A","-11606G","-11607T","-11608A","-11609C","-11610T","-11611A","-11612A","-11613G","-11614A","-11615A","-11616T","-11617T","-11618G","-11619G","-11620G","-11621C","-11622A","-11623A","-11624A","-11625C","-11626A","-11627T","-11628A","-11629A","-11630G","-11631A","-11632C","-11633A","-11634T","-11635G","-11636T","-11637C","-11638A","-11639C","-11640A","-11641A","-11642A","-11643G","-11644A","-11645C","-11646C","-11647C","-11648T","-11649T","-11650T","-11651T","-11652T","-11653G","-11654T","-11655A","-11656T","-11657G","-11658T","-11659A","-11660T","-11661A","-11662A","-11663G","-11664T","-11665G","-11666T","-11667A","-11668G","-11669A","-11670A","-11671A","-11672T","-11673T","-11674A","-11675T","-11676A","-11677A","-11678C","-11679A","-11680T","-11681C","-11682C","-11683A","-11684T","-11685A","-11686G","-11687T","-11688T","-11689G","-11690G","-11691A","-11692T","-11693T","-11694C","-11695A","-11696C","-11697A","-11698T","-11699A","-11700G","-11701G","-11702T","-11703G","-11704T","-11705C","-11706C","-11707A","-11708A","-11709T","-11710C","-11711G","-11712G","-11713G","-11714A","-11715T","-11716C","-11717T","-11718C","-11719T","-11720C","-11721C","-11722A","-11723T","-11724C","-11725A","-11726T","-11727C","-11728G","-11729A","-11730G","-11731A","-11732T","-11733G","-11734A","-11735T","-11736T","-11737G","-11738A","-11739C","-11740G","-11741G","-11742C","-11743A","-11744T","-11745C","-11746T","-11747C","-11748C","-11749C","-11750C","-11751C","-11752T","-11753T","-11754C","-11755C","-11756T","-11757T","-11758T","-11759T","-11760T","-11761T","-11762A","-11763G","-11764T","-11765A","-11766G","-11767A","-11768T","-11769A","-11770T","-11771T","-11772T","-11773C","-11774A","-11775T","-11776C","-11777G","-11778T","-11779G","-11780T","-11781A","-11782A","-11783G","-11784A","-11785A","-11786T","-11787C","-11788A","-11789A","-11790T","-11791A","-11792T","-11793T","-11794A","-11795A","-11796T","-11797A","-11798T","-11799T","-11800T","-11801C","-11802T","-11803A","-11804A","-11805A","-11806G","-11807T","-11808A","-11809T","-11810C","-11811T","-11812G","-11813T","-11814G","-11815T","-11816A","-11817T","-11818A","-11819G","-11820C","-11821C","-11822T","-11823C","-11824T","-11825T","-11826T","-11827A","-11828T","-11829T","-11830T","-11831A","-11832C","-11833C","-11834A","-11835C","-11836A","-11837G","-11838C","-11839T","-11840C","-11841C","-11842A","-11843T","-11844A","-11845T","-11846T","-11847C","-11848C","-11849A","-11850A","-11851C","-11852A","-11853T","-11854G","-11855C","-11856A","-11857T","-11858T","-11859C","-11860C","-11861A","-11862C","-11863T","-11864A","-11865G","-11866A","-11867G","-11868G","-11869G","-11870A","-11871T","-11872A","-11873T","-11874C","-11875G","-11876A","-11877T","-11878A","-11879T","-11880C","-11881G","-11882C","-11883C","-11884G","-11885A","-11886A","-11887T","-11888G","-11889T","-11890C","-11891A","-11892T","-11893A","-11894T","-11895A","-11896C","-11897T","-11898C","-11899A","-11900A","-11901T","-11902T","-11903A","-11904G","-11905T","-11906A","-11907T","-11908A","-11909T","-11910G","-11911T","-11912T","-11913G","-11914G","-11915A","-11916G","-11917G","-11918A","-11919C","-11920A","-11921T","-11922C","-11923C","-11924G","-11925A","-11926G","-11927T","-11928T","-11929C","-11930A","-11931T","-11932T","-11933G","-11934T","-11935T","-11936T","-11937T","-11938C","-11939A","-11940A","-11941T","-11942A","-11943T","-11944C","-11945A","-11946A","-11947A","-11948G","-11949A","-11950G","-11951A","-11952T","-11953G","-11954G","-11955T","-11956T","-11957T","-11958C","-11959C","-11960T","-11961T","-11962A","-11963T","-11964C","-11965A","-11966T","-11967T","-11968T","-11969C","-11970T","-11971C","-11972C","-11973A","-11974T","-11975A","-11976G","-11977T","-11978G","-11979G","-11980T","-11981A","-11982C","-11983A","-11984A","-11985T","-11986A","-11987C","-11988T","-11989A","-11990C","-11991A","-11992C","-11993A","-11994T","-11995T","-11996A","-11997T","-11998T","-11999C","-12000C","-12001G","-12002T","-12003A","-12004C","-12005G","-12006G","-12007C","-12008T","-12009T","-12010T","-12011C","-12012C","-12013A","-12014T","-12015T","-12016C","-12017T","-12018C","-12019C","-12020A","-12021A","-12022A","-12023A","-12024A","-12025C","-12026A","-12027A","-12028T","-12029T","-12030T","-12031T","-12032A","-12033C","-12034C","-12035A","-12036A","-12037A","-12038T","-12039C","-12040T","-12041A","-12042A","-12043A","-12044T","-12045C","-12046T","-12047A","-12048C","-12049A","-12050T","-12051C","-12052T","-12053T","-12054T","-12055A","-12056T","-12057T","-12058G","-12059T","-12060A","-12061T","-12062C","-12063T","-12064A","-12065T","-12066A","-12067A","-12068T","-12069C","-12070A","-12071C","-12072T","-12073A","-12074T","-12075T","-12076T","-12077A","-12078G","-12079A","-12080T","-12081A","-12082A","-12083T","-12084C","-12085A","-12086G","-12087C","-12088C","-12089A","-12090T","-12091A","-12092A","-12093T","-12094T","-12095C","-12096C","-12097T","-12098C","-12099G","-12100A","-12101G","-12102T","-12103G","-12104C","-12105A","-12106A","-12107C","-12108A","-12109T","-12110G","-12111T","-12112T","-12113A","-12114G","-12115A","-12116T","-12117C","-12118G","-12119T","-12120C","-12121T","-12122A","-12123T","-12124A","-12125T","-12126A","-12127T","-12128G","-12129A","-12130A","-12131T","-12132A","-12133A","-12134G","-12135C","-12136C","-12137G","-12138T","-12139G","-12140T","-12141T","-12142A","-12143T","-12144C","-12145T","-12146A","-12147T","-12148T","-12149C","-12150C","-12151T","-12152T","-12153T","-12154C","-12155A","-12156T","-12157T","-12158A","-12159A","-12160C","-12161A","-12162A","-12163T","-12164T","-12165T","-12166A","-12167A","-12168C","-12169G","-12170A","-12171T","-12172G","-12173T","-12174C","-12175T","-12176A","-12177T","-12178A","-12179T","-12180C","-12181T","-12182A","-12183T","-12184A","-12185T","-12186G","-12187A","-12188G","-12189A","-12190T","-12191G","-12192A","-12193C","-12194T","-12195T","-12196A","-12197A","-12198T","-12199A","-12200T","-12201A","-12202A","-12203T","-12204A","-12205T","-12206T","-12207G","-12208A","-12209A","-12210G","-12211A","-12212G","-12213C","-12214T","-12215G","-12216T","-12217A","-12218C","-12219A","-12220A","-12221T","-12222A","-12223G","-12224T","-12225T","-12226T","-12227T","-12228T","-12229A","-12230T","-12231C","-12232T","-12233A","-12234T","-12235A","-12236G","-12237A","-12238A","G40242A","C40335T","C127609T","G139582A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG023":["-222S","-223I","-224D","-225K","-226N","-227Y","-228C","-229T","-230A","-231L","-232Q","-233Y","-234Y","-235I","-236K","-237S","-238S","-239H","-240I","-241D","-242I","-243D","-244I","-245V","-246K","-247L","-248L","-249M","-250K","-251G","-252I","-253D","-254N","-255T","-256A","-257Y","-258S","-259Y","-260I","-261D","-262D","-263L","-264T","-265C","-266C","-267T","-268R","-269G","-270I","-271M","-272A","-273D","-274Y","-275L","-276N","-277S","-278D","-279Y","-280R","-281Y","-282N","-283K","-284D","-285V","-286D","-287L","-288D","-289L","-290V","-291K","-292L","-293F","-294L","-295E","-296N","-297G","-298K","-299P","-300Y","-301G","-302I","-303M","-304C","-305S","-306I","-307V","-308P","-309L","-310W","-311R","-312N","-313D","-314K","-315E","-316T","-317I","-318S","-319L","-320I","-321L","-322K","-323T","-324M","-325N","-326S","-327D","-328V","-329L","-330Q","-331H","-332I","-333L","-334I","-335E","-336Y","-337M","-338T","-339F","-340G","-341D","-342I","-343D","-344I","-345P","-346L","-347V","-348E","-349C","-350M","-351L","-352E","-353Y","-354G","-355A","-356V","-357V","-358N","-359K","-360E","-361A","-362I","-363H","-364R","-365Y","-366F","-367R","-368N","-369I","-370N","-371I","-372D","-373S","-374Y","-375T","-376M","-377K","-378Y","-379L","-380L","-381K","-382K","-383E","-384G","-385G","-386D","-387A","-388V","-389N","-390H","-391L","-392D","-393D","-394G","-395E","-396I","-397P","-398I","-399G","-400H","-401L","-402C","-403E","-404S","-405N","-406Y","-407G","-408C","-409Y","-410N","-411F","-412Y","-413T","-414Y","-415T","-416Y","-417K","-418K","-419G","-420L","-421C","-422D","-423M","-424S","-425Y","-426V","-427C","-428P","-429I","-430L","-431S","-432T","-433I","-434N","-435I","-436C","-437L","-438P","-439Y","-440L","-441K","-442D","-443I","-444N","-445M","-446I","-447D","-448K","-449R","-450G","-451E","-452T","-453L","-454L","-455H","-456K","-457A","-458V","-459R","-460Y","-461N","-462K","-463Q","-464S","-465L","-466V","-467S","-468L","-469L","-470L","-471E","-472S","-473G","-474S","-475D","-476V","-477N","-478I","-479R","-480S","-481N","-482N","-483G","-484Y","-485T","-486C","-487I","-488T","-489I","-490A","-491I","-492N","-493E","-494S","-495R","-496N","-497I","-498E","-499L","-500L","-501K","-502M","-503L","-504L","-505C","-506H","-507K","-508P","-509T","-510L","-511D","-512C","-513V","-514I","-515D","-516S","-517L","-518S","-519E","-520V","-521S","-522N","-523I","-524V","-525D"],"OPG058":["E34K"]},"labels":{"aa":"OPG023: -222S, -223I, -224D, -225K, -226N, -227Y, -228C, -229T, -230A, -231L, -232Q, -233Y, -234Y, -235I, -236K, -237S, -238S, -239H, -240I, -241D, -242I, -243D, -244I, -245V, -246K, -247L, -248L, -249M, -250K, -251G, -252I, -253D, -254N, -255T, -256A, -257Y, -258S, -259Y, -260I, -261D, -262D, -263L, -264T, -265C, -266C, -267T, -268R, -269G, -270I, -271M, -272A, -273D, -274Y, -275L, -276N, -277S, -278D, -279Y, -280R, -281Y, -282N, -283K, -284D, -285V, -286D, -287L, -288D, -289L, -290V, -291K, -292L, -293F, -294L, -295E, -296N, -297G, -298K, -299P, -300Y, -301G, -302I, -303M, -304C, -305S, -306I, -307V, -308P, -309L, -310W, -311R, -312N, -313D, -314K, -315E, -316T, -317I, -318S, -319L, -320I, -321L, -322K, -323T, -324M, -325N, -326S, -327D, -328V, -329L, -330Q, -331H, -332I, -333L, -334I, -335E, -336Y, -337M, -338T, -339F, -340G, -341D, -342I, -343D, -344I, -345P, -346L, -347V, -348E, -349C, -350M, -351L, -352E, -353Y, -354G, -355A, -356V, -357V, -358N, -359K, -360E, -361A, -362I, -363H, -364R, -365Y, -366F, -367R, -368N, -369I, -370N, -371I, -372D, -373S, -374Y, -375T, -376M, -377K, -378Y, -379L, -380L, -381K, -382K, -383E, -384G, -385G, -386D, -387A, -388V, -389N, -390H, -391L, -392D, -393D, -394G, -395E, -396I, -397P, -398I, -399G, -400H, -401L, -402C, -403E, -404S, -405N, -406Y, -407G, -408C, -409Y, -410N, -411F, -412Y, -413T, -414Y, -415T, -416Y, -417K, -418K, -419G, -420L, -421C, -422D, -423M, -424S, -425Y, -426V, -427C, -428P, -429I, -430L, -431S, -432T, -433I, -434N, -435I, -436C, -437L, -438P, -439Y, -440L, -441K, -442D, -443I, -444N, -445M, -446I, -447D, -448K, -449R, -450G, -451E, -452T, -453L, -454L, -455H, -456K, -457A, -458V, -459R, -460Y, -461N, -462K, -463Q, -464S, -465L, -466V, -467S, -468L, -469L, -470L, -471E, -472S, -473G, -474S, -475D, -476V, -477N, -478I, -479R, -480S, -481N, -482N, -483G, -484Y, -485T, -486C, -487I, -488T, -489I, -490A, -491I, -492N, -493E, -494S, -495R, -496N, -497I, -498E, -499L, -500L, -501K, -502M, -503L, -504L, -505C, -506H, -507K, -508P, -509T, -510L, -511D, -512C, -513V, -514I, -515D, -516S, -517L, -518S, -519E, -520V, -521S, -522N, -523I, -524V, -525D; OPG058: E34K"}},"children":[{"name":"OP819950","node_attrs":{"div":70,"accession":"OP819950","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.15"},"strain":{"value":"MET_INS_MPX_0956_C"},"date":{"value":"2022-10-12"},"strain_display":{"value":"Colombia/OP819950/2022-10-12"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G144284A","C171808T","G196973-","A196974-","A196975-"],"OPG165":["D257N"],"OPG199":["S274L"]},"labels":{"aa":"OPG165: D257N; OPG199: S274L"}}},{"name":"OP693654","node_attrs":{"div":68,"accession":"OP693654","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.15"},"strain":{"value":"DC_INS_MPX_0722_L"},"date":{"value":"2022-08-23"},"strain_display":{"value":"Colombia/OP693654/2022-08-23"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A2840-","T2841-","C2842-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP959066","node_attrs":{"div":68,"accession":"OP959066","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"lineage":{"value":"B.1.15"},"strain":{"value":"CES-UNIMOL-MPX-202203848-L"},"date":{"value":"2022-09-14"},"strain_display":{"value":"Colombia/OP959066/2022-09-14"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OR035721","node_attrs":{"div":70,"accession":"OR035721","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/UZ_REGA_115"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035721/2022-10-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C21324T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G180556A","T196712-","A196713-","T196714-"]}}},{"name":"OR086972","node_attrs":{"div":73,"accession":"OR086972","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/UZ_REGA_163/Belgium/2022"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR086972/2022-07-27"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G31180A","C142626T","G158549A","G159341A","C170750T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG163":["S142L"],"OPG185":["G142E"],"OPG198":["A238V"]},"labels":{"aa":"OPG163: S142L; OPG185: G142E; OPG198: A238V"}}}]}]},{"name":"NODE_0000072","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["G175093A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG204":["D188N"]},"labels":{"aa":"OPG204: D188N","clade":"B.1.13"}},"children":[{"name":"OP536663","node_attrs":{"div":64,"accession":"OP536663","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV-USA-IL-IDPH-002"},"date":{"value":"2022-08-04"},"strain_display":{"value":"USA/OP536663/2022-08-04"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G119424A","G125452A","-196615A","-196616A","-196617A"],"OPG136":["S55L"],"OPG146":["S63L"]},"labels":{"aa":"OPG136: S55L; OPG146: S63L"}}},{"name":"NODE_0000073","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["G22814A","G55162A","C118921T","G137128A","G167910A","A173316-","T173317-"],"OPG038":["H116Y"],"OPG074":["S655L"],"OPG136":["D223N"],"OPG193":["E193K"]},"labels":{"aa":"OPG038: H116Y; OPG074: S655L; OPG136: D223N; OPG193: E193K"}},"children":[{"name":"OQ320456","node_attrs":{"div":67,"accession":"OQ320456","author":{"author":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y.","value":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV_USA_2022_KS0004"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ320456/2022-10-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OQ721921","node_attrs":{"div":68,"accession":"OQ721921","author":{"author":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y.","value":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV_USA_2022_KS0005"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721921/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C110297T","A173314-","T173315-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-"]}}}]},{"name":"NODE_0000074","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["C132520T"]}},"children":[{"name":"OP257254","node_attrs":{"div":63,"accession":"OP257254","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.13"},"strain":{"value":"MpxV/human/USA/OH-UW-073812/2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP257254/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP536733","node_attrs":{"div":63,"accession":"OP536733","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV-USA-IL-IDPH-072"},"date":{"value":"2022-06-30"},"strain_display":{"value":"USA/OP536733/2022-06-30"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-196615A","-196616A","-196617A"]}}},{"name":"OP451003","node_attrs":{"div":65,"accession":"OP451003","author":{"author":"Gigante,C.M.,Wang,X.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Ostadkar,R.,Li,Y.","value":"Gigante,C.M.,Wang,X.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Ostadkar,R.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV_USA_2022_MN0006"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OP451003/2022-07-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","G127678A","G165086A","G173341-","A173342-","A173343-","T173344-","T173345-","A173346-","T173347-","A173348-","A173349-","A173350-","A173351-","T173352-","T173353-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"],"OPG149":["M161I"]},"labels":{"aa":"OPG149: M161I"}}},{"name":"NODE_0000075","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["C21383T","G85431A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG037":["G351S"],"OPG106":["S23F"]},"labels":{"aa":"OPG037: G351S; OPG106: S23F"}},"children":[{"name":"OP270476","node_attrs":{"div":66,"accession":"OP270476","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Friesen,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Friesen,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV/Germany/2022/RKI287"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP270476/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C172851T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-"]}}},{"name":"OQ773520","node_attrs":{"div":67,"accession":"OQ773520","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV/Germany/2022/ON/RKI901"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773520/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C146446T","C147140T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG170":["M111I"]},"labels":{"aa":"OPG170: M111I"}}}]},{"name":"NODE_0000076","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["G99832A","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"],"OPG118":["D463N"]},"labels":{"aa":"OPG118: D463N"}},"children":[{"name":"OP743957","node_attrs":{"div":67,"accession":"OP743957","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.13"},"strain":{"value":"MpxV/human/USA/OH-UW-080634/2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP743957/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C16327T","G61713A","G135355A"]}}},{"name":"OR160418","node_attrs":{"div":70,"accession":"OR160418","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"lineage":{"value":"B.1.13"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-052-0034/2023"},"date":{"value":"2023-05-10"},"strain_display":{"value":"USA/OR160418/2023-05-10"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C27520T","G58883A","G102186A","G129583A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G171410A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C182950T"],"OPG043":["A146T"],"OPG121":["E133K"],"OPG210":["S532L"]},"labels":{"aa":"OPG043: A146T; OPG121: E133K; OPG210: S532L"}}}]}]}]},{"name":"NODE_0000077","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.6"}},"branch_attrs":{"mutations":{"nuc":["G111029A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]},"labels":{"clade":"B.1.6"}},"children":[{"name":"OP289782","node_attrs":{"div":62,"accession":"OP289782","author":{"author":"Silva,I.,Jimenez,V.,Hurtado,V.,Barcena,L.","value":"Silva,I.,Jimenez,V.,Hurtado,V.,Barcena,L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Peru"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"lineage":{"value":"B.1.6"},"strain":{"value":"LIM-INS-001"},"date":{"value":"2022-06-25"},"strain_display":{"value":"Peru/OP289782/2022-06-25"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-196615A","-196616A","-196617A"]}}},{"name":"OP431402","node_attrs":{"div":63,"accession":"OP431402","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.6"},"strain":{"value":"ANT-LDSP-ANT-MPX-22752-O"},"date":{"value":"2022-08-18"},"strain_display":{"value":"Colombia/OP431402/2022-08-18"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G15814A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP536765","node_attrs":{"div":64,"accession":"OP536765","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.6"},"strain":{"value":"9000387"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP536765/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G59112A","C87978T"]}}},{"name":"OP837474","node_attrs":{"div":63,"accession":"OP837474","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.6"},"strain":{"value":"DC_INS_MPX_0996_L"},"date":{"value":"2022-09-19"},"strain_display":{"value":"Colombia/OP837474/2022-09-19"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G29656A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"],"OPG046":["S25L"]},"labels":{"aa":"OPG046: S25L"}}},{"name":"OQ348868","node_attrs":{"div":64,"accession":"OQ348868","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDPH, VRDL"},"lineage":{"value":"B.1.6"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000120/2022"},"date":{"value":"2022-09-20"},"strain_display":{"value":"USA/OQ348868/2022-09-20"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","G150364A","C166930T"],"OPG176":["E186K"],"OPG192":["S67L"]},"labels":{"aa":"OPG176: E186K; OPG192: S67L"}}},{"name":"OQ503831","node_attrs":{"div":66,"accession":"OQ503831","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.6"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00408/2023"},"date":{"value":"2023-01-11"},"strain_display":{"value":"USA/OQ503831/2023-01-11"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","G10945A","G39515A","C44627T","G56276A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A196614-"],"OPG064":["M424I"]},"labels":{"aa":"OPG064: M424I"}}},{"name":"OP320555","node_attrs":{"div":62,"accession":"OP320555","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Peru"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"lineage":{"value":"B.1.6"},"strain":{"value":"LIM-INS-021"},"date":{"value":"2022-07-09"},"strain_display":{"value":"Peru/OP320555/2022-07-09"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP289783","node_attrs":{"div":62,"accession":"OP289783","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Mestanza,O.,Lope,P.,Nunez,A.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Mestanza,O.,Lope,P.,Nunez,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Peru"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"lineage":{"value":"B.1.6"},"strain":{"value":"LIM-INS-003"},"date":{"value":"2022-06-27"},"strain_display":{"value":"Peru/OP289783/2022-06-27"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000079","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.6"}},"branch_attrs":{"mutations":{"nuc":["C14098T","C84063T","G142493A","G151324A","C170573T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C187332T","C196696-","G196697-","A196698-"],"OPG163":["D98N"],"OPG198":["S179L"]},"labels":{"aa":"OPG163: D98N; OPG198: S179L"}},"children":[{"name":"OQ331003","node_attrs":{"div":70,"accession":"OQ331003","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.6"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00392/2022"},"date":{"value":"2022-12-06"},"strain_display":{"value":"USA/OQ331003/2022-12-06"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G97749A","G188726A"]}}},{"name":"OR499960","node_attrs":{"div":74,"accession":"OR499960","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1.6"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00503/2023"},"date":{"value":"2023-03-15"},"strain_display":{"value":"USA/OR499960/2023-03-15"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G6746A","C39266T","C63819T","G106927A","G138862A","G169213A"],"OPG083":["V300I"],"OPG125":["T243M"],"OPG156":["S183F"]},"labels":{"aa":"OPG083: V300I; OPG125: T243M; OPG156: S183F"}}}]},{"name":"NODE_0000080","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.6"}},"branch_attrs":{"mutations":{"nuc":["G63811A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G167862A","C170130T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179266-","T179267-","A179270-","T179271-","A179272-","T179273-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","A179282-"],"OPG193":["D177N"]},"labels":{"aa":"OPG193: D177N"}},"children":[{"name":"OQ696099","node_attrs":{"div":66,"accession":"OQ696099","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.6"},"strain":{"value":"ANT-LDSP-ANT-MPX-30518C"},"date":{"value":"2022-11-09"},"strain_display":{"value":"Colombia/OQ696099/2022-11-09"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G132863A","-179266A","-179267T","-179270A","-179271T","-179272A","-179273T","-179275T","-179276T","-179277T","-179278A","-179279A","-179280A","-179282A"]}}},{"name":"OQ696077","node_attrs":{"div":65,"accession":"OQ696077","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.6"},"strain":{"value":"ANT-LDSP-ANT-MPX-29396O"},"date":{"value":"2022-10-27"},"strain_display":{"value":"Colombia/OQ696077/2022-10-27"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179265-","G179268-","G179269-","C179274-","G179281-"]}}}]}]},{"name":"NODE_0000081","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["G9963A","T133102-","C148268T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG021":["R126K"]},"labels":{"aa":"OPG021: R126K","clade":"B.1.19"}},"children":[{"name":"OP270026","node_attrs":{"div":63,"accession":"OP270026","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.19"},"strain":{"value":"MpxV/human/CAN/UN-NML-4017/2022"},"date":{"value":"2022-07-05"},"strain_display":{"value":"Canada/OP270026/2022-07-05"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-133102T","-196615A","-196616A","-196617A"]}}},{"name":"OP382481","node_attrs":{"div":65,"accession":"OP382481","author":{"author":"Colson,P.","value":"Colson,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"lineage":{"value":"B.1.19"},"strain":{"value":"hMPXV-IHU00004"},"date":{"value":"2022-07-04"},"strain_display":{"value":"France/OP382481/2022-07-04"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G115549A","C163653T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"],"OPG133":["P50S"]},"labels":{"aa":"OPG133: P50S"}}},{"name":"OP838893","node_attrs":{"div":63,"accession":"OP838893","author":{"author":"Viscardi,M.,Cozzolino,L.,De Martinis,C.,Cardillo,L.,Fusco,G.","value":"Viscardi,M.,Cozzolino,L.,De Martinis,C.,Cardillo,L.,Fusco,G."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Italy"},"clade_membership":{"value":"IIb"},"institution":{"value":"Istituto Zooprofilattico Sperimentale del Mezzogiorno, Hanimal Health"},"lineage":{"value":"B.1.19"},"strain":{"value":"ID6821"},"date":{"value":"2022-06-21"},"strain_display":{"value":"Italy/OP838893/2022-06-21"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","T133100-","T133101-","C133103-","G133104-","A133105-","A133106-","T133107-","T133108-","C133109-","A133110-","C133111-","G133112-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A157678-","A157679-","A157680-","A157681-","T157682-","T157683-","T157684-","T157685-","A157686-","A157687-","G157688-","C157689-","G157690-","A157691-","T157692-","G157693-","A157694-","T157695-","A157696-","T163214-","C163215-","T163216-","T163217-","A163218-","T163219-","A163220-","T163221-","A163417-","A163418-","T163419-","T163420-","C163421-","T163422-","T163423-","C163424-","C163425-","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","G174537-","A174538-","T174539-","G174540-","A174541-","A174542-","A180482-","T180483-","T180484-","A180485-","A180486-","A180487-","A180488-","A180489-","A181114-","T181115-","T181116-","C181117-","C181118-","T181119-","T181120-","A181121-","T181122-","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-"],"OPG159":["N124-","Y125-","N126-"],"OPG189":["N29-","S30-","S31-"]},"labels":{"aa":"OPG159: N124-, Y125-, N126-; OPG189: N29-, S30-, S31-"}}},{"name":"OR035726","node_attrs":{"div":65,"accession":"OR035726","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV/UZ_REGA_120"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035726/2022-10-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C22739T","-133102T","G133104A","G133231A","T137560-","G164487A"],"OPG038":["E141K"]},"labels":{"aa":"OPG038: E141K"}}},{"name":"OR086965","node_attrs":{"div":68,"accession":"OR086965","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV/UZ_REGA_156/Belgium/2022"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR086965/2022-07-27"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C71016T","G77415A","T133101-","G133319A","C176069T","G181309A"],"OPG089":["S384L"]},"labels":{"aa":"OPG089: S384L"}}},{"name":"NODE_0000082","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["G150003A","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"]}},"children":[{"name":"OQ172215","node_attrs":{"div":68,"accession":"OQ172215","author":{"author":"Zeggagh,J.,Ferraris,O.,Salmona,M.,Tarantola,A.,Molina,J.M.,Delaugerre,C.","value":"Zeggagh,J.,Ferraris,O.,Salmona,M.,Tarantola,A.,Molina,J.M.,Delaugerre,C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"Hopital Saint Louis, Paris"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV-1047"},"date":{"value":"2022-06-07"},"strain_display":{"value":"France/OQ172215/2022-06-07"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A2591G","A31053G","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133171-","C133172-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T133639-","A150635-","A152676-","T152686-","T155897A","C173533A","A179077T","A179079T","A179081T","C179082T","A179083T","A179086T","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","T194619C","T194627G"],"OPG002":["F54S"],"OPG002_dup":["F54S","C57G"],"OPG047":["C48R"]},"labels":{"aa":"OPG002: F54S; OPG002_dup: F54S, C57G; OPG047: C48R"}}},{"name":"OQ427121","node_attrs":{"div":65,"accession":"OQ427121","author":{"author":"Gigante,C.,Cogswell,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Grenz,L.,Li,Y.","value":"Gigante,C.,Cogswell,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Grenz,L.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV_USA_2022_OR0008"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OQ427121/2022-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-133102T","C150140T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"],"OPG176":["S111L"]},"labels":{"aa":"OPG176: S111L"}}},{"name":"OR095050","node_attrs":{"div":67,"accession":"OR095050","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV/UZ_REGA_232/Belgium/2022"},"date":{"value":"2022-08-12"},"strain_display":{"value":"Belgium/OR095050/2022-08-12"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G57033A","G77415A","G83609A","T133101-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C196750-","T196751-","A196752-"]}}},{"name":"NODE_0000083","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["C74417T","-133102T"],"OPG094":["S213L"]},"labels":{"aa":"OPG094: S213L"}},"children":[{"name":"OP205108","node_attrs":{"div":65,"accession":"OP205108","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV_UK_2022_9000145"},"date":{"value":"2022-06-16"},"strain_display":{"value":"United Kingdom/OP205108/2022-06-16"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP413717","node_attrs":{"div":65,"accession":"OP413717","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.19"},"strain":{"value":"9000353"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP413717/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP536781","node_attrs":{"div":66,"accession":"OP536781","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.19"},"strain":{"value":"9000405"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536781/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","C62868T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"]}}}]},{"name":"NODE_0000084","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["-133102T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A169944T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG197":["E92V"]},"labels":{"aa":"OPG197: E92V"}},"children":[{"name":"OP555622","node_attrs":{"div":65,"accession":"OP555622","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.19"},"strain":{"value":"Monkeypox/PT0551/2022"},"date":{"value":"2022-08-26"},"strain_display":{"value":"Portugal/OP555622/2022-08-26"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000085","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["C185326T","-196615A"],"OPG210":["S1324L"]},"labels":{"aa":"OPG210: S1324L"}},"children":[{"name":"OP555643","node_attrs":{"div":67,"accession":"OP555643","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.19"},"strain":{"value":"Monkeypox/PT0572/2022"},"date":{"value":"2022-09-05"},"strain_display":{"value":"Portugal/OP555643/2022-09-05"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","C55057T"],"OPG073":["E29K"]},"labels":{"aa":"OPG073: E29K"}}},{"name":"OQ159056","node_attrs":{"div":70,"accession":"OQ159056","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV/Germany/2022/ON/RKI661"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OQ159056/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C2652T","G9584A","C87741T","G98995A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG002":["D34N"],"OPG118":["E184K"]},"labels":{"aa":"OPG002: D34N; OPG118: E184K"}}}]}]}]}]},{"name":"NODE_0000086","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-607T","G53326A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-196615A"]}},"children":[{"name":"OR264430","node_attrs":{"div":64,"accession":"OR264430","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1"},"strain":{"value":"51_B"},"date":{"value":"2022-09-05"},"strain_display":{"value":"Australia/OR264430/2022-09-05"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C15582T","C121104T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG138":["R10K"]},"labels":{"aa":"OPG138: R10K"}}},{"name":"NODE_0000087","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["T133102-","C164385T","C187620T"]},"labels":{"clade":"B.1.20"}},"children":[{"name":"OQ320441","node_attrs":{"div":64,"accession":"OQ320441","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV_USA_2022_TX0040"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ320441/2022-10-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"]}}},{"name":"OQ054239","node_attrs":{"div":65,"accession":"OQ054239","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV_USA_2022_TX0017"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ054239/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-133102T","G176549A","-179194A","-179195T","-179196A","-179197T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG205":["M298I"]},"labels":{"aa":"OPG205: M298I"}}},{"name":"OQ427125","node_attrs":{"div":66,"accession":"OQ427125","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV_USA_2022_TX0044"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ427125/2022-10-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G48645A","G130027A","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-"],"OPG068":["E149K"]},"labels":{"aa":"OPG068: E149K"}}},{"name":"NODE_0000088","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["T602-","T603-","T604-","T605-","T606-","T607-","-133102T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177398A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A196610-","A196611-","A196612-","A196613-","A196614-","A196615-"]}},"children":[{"name":"OQ918695","node_attrs":{"div":65,"accession":"OQ918695","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00484/2023"},"date":{"value":"2023-02-07"},"strain_display":{"value":"USA/OQ918695/2023-02-07"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ644783","node_attrs":{"div":65,"accession":"OQ644783","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00477/2023"},"date":{"value":"2023-01-17"},"strain_display":{"value":"USA/OQ644783/2023-01-17"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T179179-","A179180-"]}}},{"name":"NODE_0000089","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["G36027A","C72221T","A150586-","T150587-","A150588-","T150589-","A150591-","T150592-","A150595-","T150596-","A150597-","T150598-","A150600-","T150601-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A"],"OPG055":["R353C"],"OPG092":["E243K"]},"labels":{"aa":"OPG055: R353C; OPG092: E243K"}},"children":[{"name":"OQ427126","node_attrs":{"div":67,"accession":"OQ427126","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV_USA_2022_TX0045"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"USA/OQ427126/2022-11-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-"]}}},{"name":"OQ626773","node_attrs":{"div":71,"accession":"OQ626773","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV22/human/USA-NE-375"},"date":{"value":"2022-12-28"},"strain_display":{"value":"USA/OQ626773/2022-12-28"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-602T","-603T","-604T","-605T","-606T","-607T","-608T","-609T","C11175A","G102694A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C161572T","G164017A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196610A","-196611A","-196612A","-196613A","-196614A","-196615A","-196616A","-196617A"],"OPG023":["G576*"],"OPG189":["E229K"]},"labels":{"aa":"OPG023: G576*; OPG189: E229K"}}}]},{"name":"NODE_0000090","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["C177899T","T179179-","A179180-"]}},"children":[{"name":"OR499966","node_attrs":{"div":67,"accession":"OR499966","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00509/2023"},"date":{"value":"2023-03-31"},"strain_display":{"value":"USA/OR499966/2023-03-31"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G115293A"],"OPG133":["A135V"]},"labels":{"aa":"OPG133: A135V"}}},{"name":"NODE_0000091","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["C20453T","T164946C"]}},"children":[{"name":"OR449306","node_attrs":{"div":68,"accession":"OR449306","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Germany/2023/RKI1020"},"date":{"value":"2023-07-XX"},"strain_display":{"value":"Germany/OR449306/2023-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-602T","-603T","-604T","-605T","-606T","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"]}}},{"name":"OR421480","node_attrs":{"div":68,"accession":"OR421480","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"lineage":{"value":"B.1.20"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0023/2023"},"date":{"value":"2023-05-07"},"strain_display":{"value":"USA/OR421480/2023-05-07"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OR500001","node_attrs":{"div":69,"accession":"OR500001","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00545/2023"},"date":{"value":"2023-06-10"},"strain_display":{"value":"USA/OR500001/2023-06-10"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C2313T","G194897A"],"OPG002":["D147N"],"OPG002_dup":["D147N"]},"labels":{"aa":"OPG002: D147N; OPG002_dup: D147N"}}},{"name":"OR499954","node_attrs":{"div":68,"accession":"OR499954","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00497/2023"},"date":{"value":"2023-04-28"},"strain_display":{"value":"USA/OR499954/2023-04-28"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000092","node_attrs":{"div":70,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["-604T","-605T","-606T","C174050T","C180618T"],"OPG209":["S34L"]},"labels":{"aa":"OPG209: S34L"}},"children":[{"name":"OR725698","node_attrs":{"div":72,"accession":"OR725698","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"lineage":{"value":"B.1.20"},"strain":{"value":"hMpxV/USA/IL-RIPHL-052-0100/2023"},"date":{"value":"2023-08-22"},"strain_display":{"value":"USA/OR725698/2023-08-22"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C105798T","G148126A"]}}},{"name":"OR725697","node_attrs":{"div":72,"accession":"OR725697","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"lineage":{"value":"B.1.20"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0107/2023"},"date":{"value":"2023-09-06"},"strain_display":{"value":"USA/OR725697/2023-09-06"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","G113508A","C136791T"],"OPG153":["E293K"]},"labels":{"aa":"OPG153: E293K"}}},{"name":"OR473619","node_attrs":{"div":72,"accession":"OR473619","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"lineage":{"value":"B.1.20"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0088/2023"},"date":{"value":"2023-07-17"},"strain_display":{"value":"USA/OR473619/2023-07-17"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C61724T","C111728T"],"OPG080":["E99K"],"OPG130":["D59N"]},"labels":{"aa":"OPG080: E99K; OPG130: D59N"}}}]}]}]}]}]}]},{"name":"NODE_0000093","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["C18133T","G67611A","G130231A","G159277A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179217C","-179226C","-179235C"],"OPG185":["E121K"]},"labels":{"aa":"OPG185: E121K","clade":"B.1.11"}},"children":[{"name":"OP169336","node_attrs":{"div":65,"accession":"OP169336","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.11"},"strain":{"value":"MpxV/human/USA/WA-UW-070499/2022"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OP169336/2022-07-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OP390178","node_attrs":{"div":65,"accession":"OP390178","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"lineage":{"value":"B.1.11"},"strain":{"value":"MAG-UNIMOL-MPX-292982-L"},"date":{"value":"2022-08-20"},"strain_display":{"value":"Colombia/OP390178/2022-08-20"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP555545","node_attrs":{"div":65,"accession":"OP555545","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.11"},"strain":{"value":"Monkeypox/PT0466/2022"},"date":{"value":"2022-08-05"},"strain_display":{"value":"Portugal/OP555545/2022-08-05"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","C179217-","C179226-","C179235-"]}}},{"name":"OP536702","node_attrs":{"div":65,"accession":"OP536702","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV-USA-IL-IDPH-041"},"date":{"value":"2022-06-21"},"strain_display":{"value":"USA/OP536702/2022-06-21"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"OP524006","node_attrs":{"div":66,"accession":"OP524006","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV/Germany/2022/RKI404"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP524006/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","C179217-","C179226-","C179235-","G182634A","-196615A"],"OPG210":["D427N"]},"labels":{"aa":"OPG210: D427N"}}},{"name":"OP879738","node_attrs":{"div":65,"accession":"OP879738","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"lineage":{"value":"B.1.11"},"strain":{"value":"NJ-MPXV-020-rep2"},"date":{"value":"2022-07-06"},"strain_display":{"value":"USA/OP879738/2022-07-06"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","C179217-","C179226-","C179235-"]}}},{"name":"OP819960","node_attrs":{"div":68,"accession":"OP819960","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.11"},"strain":{"value":"SAN_INS_MPX_0973_L"},"date":{"value":"2022-10-17"},"strain_display":{"value":"Colombia/OP819960/2022-10-17"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A19748-","G19749-","G19750-","C19751-","G19752-","T19753-","G27840A","C64404T","C96810T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG034":["T87-","P88-"],"OPG043":["S39F"],"OPG083":["D105N"]},"labels":{"aa":"OPG034: T87-, P88-; OPG043: S39F; OPG083: D105N"}}},{"name":"OQ148464","node_attrs":{"div":68,"accession":"OQ148464","author":{"author":"Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"lineage":{"value":"B.1.11"},"strain":{"value":"LBMB-UTP_MP-006_TOL"},"date":{"value":"2022-09-16"},"strain_display":{"value":"Colombia/OQ148464/2022-09-16"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C58682T","C170573T","G178744A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG078":["G44S"],"OPG198":["S179L"]},"labels":{"aa":"OPG078: G44S; OPG198: S179L"}}},{"name":"OP920682","node_attrs":{"div":67,"accession":"OP920682","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00344/2022"},"date":{"value":"2022-11-09"},"strain_display":{"value":"USA/OP920682/2022-11-09"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","G39327A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177273A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","C179217-","C179226-","C179235-","-196615A"],"OPG057":["A290V"],"OPG205":["D540N"]},"labels":{"aa":"OPG057: A290V; OPG205: D540N"}}},{"name":"OR035719","node_attrs":{"div":68,"accession":"OR035719","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV/UZ_REGA_113"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035719/2022-10-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133102-","C142797T","C167995T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G189258A"],"OPG164":["S7L"],"OPG193":["S221F"]},"labels":{"aa":"OPG164: S7L; OPG193: S221F"}}},{"name":"OQ957072","node_attrs":{"div":68,"accession":"OQ957072","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.11"},"strain":{"value":"ANT-LDSP-ANT-MPX-3668E"},"date":{"value":"2023-02-16"},"strain_display":{"value":"Colombia/OQ957072/2023-02-16"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C35308T","G71777A","C120979T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG054":["R230H"],"OPG138":["D52N"]},"labels":{"aa":"OPG054: R230H; OPG138: D52N"}}},{"name":"OQ696101","node_attrs":{"div":69,"accession":"OQ696101","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.11"},"strain":{"value":"ANT-LDSP-ANT-MPX-30628C"},"date":{"value":"2022-11-11"},"strain_display":{"value":"Colombia/OQ696101/2022-11-11"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G17023A","G74462A","C80742T","G113382A","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG029":["S16F"],"OPG094":["R228K"],"OPG104":["R93Q"]},"labels":{"aa":"OPG029: S16F; OPG094: R228K; OPG104: R93Q"}}},{"name":"OR095053","node_attrs":{"div":65,"accession":"OR095053","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV/UZ_REGA_235/Belgium/2022"},"date":{"value":"2022-08-12"},"strain_display":{"value":"Belgium/OR095053/2022-08-12"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000094","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["-607T","C89777T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG110":["P49L"]},"labels":{"aa":"OPG110: P49L"}},"children":[{"name":"OP628471","node_attrs":{"div":66,"accession":"OP628471","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.11"},"strain":{"value":"MpxV/human/USA/WA-UW-086901/2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP628471/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-196615A"]}}},{"name":"OR433614","node_attrs":{"div":66,"accession":"OR433614","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.11"},"strain":{"value":"MpxV/human/USA/WA-UW-094945/2022"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OR433614/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T166110-","T166111-","A166112-","A166113-","T166114-","A166115-","A166116-"]}}}]},{"name":"NODE_0000095","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["G19458A","-179194A","-179195T","-179196A","-179197T","-179198A","C179217-","C179226-","C179235-","C185455T"],"OPG034":["S183L"],"OPG210":["S1367L"]},"labels":{"aa":"OPG034: S183L; OPG210: S1367L"}},"children":[{"name":"OQ320458","node_attrs":{"div":69,"accession":"OQ320458","author":{"author":"Gigante,C.,Cleavinger,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Burroughs,M.R.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Sinn,M.,Li,Y.","value":"Gigante,C.,Cleavinger,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Burroughs,M.R.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Sinn,M.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV_USA_2022_MO0002"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ320458/2022-10-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","G149818A","T167929A","A196614-"],"OPG176":["D4N"],"OPG193":["I199N"]},"labels":{"aa":"OPG176: D4N; OPG193: I199N"}}},{"name":"OR209310","node_attrs":{"div":68,"accession":"OR209310","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV_USA_2022_TX0052"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR209310/2022-12-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G74374A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"],"OPG094":["E199K"]},"labels":{"aa":"OPG094: E199K"}}}]}]},{"name":"NODE_0000096","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["G36617A","C159779T"],"OPG055":["S156L"],"OPG185":["S288L"]},"labels":{"aa":"OPG055: S156L; OPG185: S288L","clade":"B.1.14"}},"children":[{"name":"ON694342","node_attrs":{"div":63,"accession":"ON694342","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/RKI011"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/ON694342/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP378704","node_attrs":{"div":66,"accession":"OP378704","author":{"author":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y.","value":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV_USA_2022_TX0010"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP378704/2022-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C8552T","C8597T","G46179A","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A","-196616A"],"OPG065":["S102L"]},"labels":{"aa":"OPG065: S102L"}}},{"name":"OP355563","node_attrs":{"div":63,"accession":"OP355563","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/ON/RKI302"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP355563/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","A188351-"]}}},{"name":"OP837348","node_attrs":{"div":67,"accession":"OP837348","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/RKI586"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OP837348/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C2459T","G90418A","C133943T","C134688T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G194751A"],"OPG002":["R98Q"],"OPG002_dup":["R98Q"],"OPG111":["E52K"]},"labels":{"aa":"OPG002: R98Q; OPG002_dup: R98Q; OPG111: E52K"}}},{"name":"OQ547749","node_attrs":{"div":63,"accession":"OQ547749","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/ON/RKI722"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ547749/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150563-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OR086995","node_attrs":{"div":64,"accession":"OR086995","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/UZ_REGA_186/Belgium/2022"},"date":{"value":"2022-08-03"},"strain_display":{"value":"Belgium/OR086995/2022-08-03"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G146441A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG170":["S113F"]},"labels":{"aa":"OPG170: S113F"}}},{"name":"OX009124","node_attrs":{"div":65,"accession":"OX009124","author":{"author":"Pettke,A.,Filen,F.,Asgeirsson,H.,Glans,H.,Widgren,K.,Muradrasoli,S.,Helgesson,S.,Karlberg,M.L.,Walai,N.,Bjerkner,A.,Gourle,H.,Lindsjo,O.K.,Sonden,K.","value":"Pettke,A.,Filen,F.,Asgeirsson,H.,Glans,H.,Widgren,K.,Muradrasoli,S.,Helgesson,S.,Karlberg,M.L.,Walai,N.,Bjerkner,A.,Gourle,H.,Lindsjo,O.K.,Sonden,K."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Sweden"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Agency of Sweden, Unit for Laboratory Development and Technology Transfer , Folkhalsomyndigheten, 171 82 Solna"},"lineage":{"value":"B.1.14"},"strain":{"value":"Lesion"},"date":{"value":"2022-05-22"},"strain_display":{"value":"Sweden/OX009124/2022-05-22"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T602-","T603-","T604-","T605-","T606-","A8055-","A28529-","A28530-","T47054-","T76087-","T88836-","A91705-","A92907-","T103367-","T104687-","T148344A","A148345T","A151680-","A162904-","T163342-","T163597-","A170728-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG044":["K147-"],"OPG113":["I393-"],"OPG178":["T58-"],"OPG188":["K437-"],"OPG189":["F4-"],"OPG198":["K231-"]},"labels":{"aa":"OPG044: K147-; OPG113: I393-; OPG178: T58-; OPG188: K437-; OPG189: F4-; OPG198: K231-"}}},{"name":"ON959133","node_attrs":{"div":63,"accession":"ON959133","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV_USA_2022_NY002"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/ON959133/2022-05-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"]}}},{"name":"OP451009","node_attrs":{"div":63,"accession":"OP451009","author":{"author":"Gigante,C.M.,Pearson,C.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Maloney,M.,Li,Y.","value":"Gigante,C.M.,Pearson,C.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Maloney,M.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV_USA_2022_CT0002"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OP451009/2022-07-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","T173277-","A173278-","T173279-","A173280-","T173281-","A173282-","T173283-","A173284-","T173285-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"]}}},{"name":"NODE_0000098","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["G158617A","C183790T"],"OPG210":["S812L"]},"labels":{"aa":"OPG210: S812L"}},"children":[{"name":"ON929060","node_attrs":{"div":67,"accession":"ON929060","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/RKI102"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/ON929060/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C127245T","C132437T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG149":["S17L"]},"labels":{"aa":"OPG149: S17L"}}},{"name":"OR035646","node_attrs":{"div":67,"accession":"OR035646","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/UZ_REGA_40"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR035646/2022-07-27"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C22880T","C170573T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG038":["E94K"],"OPG198":["S179L"]},"labels":{"aa":"OPG038: E94K; OPG198: S179L"}}}]},{"name":"NODE_0000099","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["G28021A"]}},"children":[{"name":"OP539922","node_attrs":{"div":66,"accession":"OP539922","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00137/2022"},"date":{"value":"2022-08-09"},"strain_display":{"value":"USA/OP539922/2022-08-09"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G109793A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G168211-","G168212-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G181818A"],"OPG210":["A155T"]},"labels":{"aa":"OPG210: A155T"}}},{"name":"OR026632","node_attrs":{"div":68,"accession":"OR026632","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Utah Public Health Laboratory, Utah Public Health Laboratory Infectious Disease submission group"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200396/2022"},"date":{"value":"2022-09-19"},"strain_display":{"value":"USA/OR026632/2022-09-19"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C25855T","G127941A","C177833T","C177917T"],"OPG042":["E415K"],"OPG150":["D55N"]},"labels":{"aa":"OPG042: E415K; OPG150: D55N"}}}]},{"name":"NODE_0000100","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G171270A","-196615A"],"OPG199":["D95N"]},"labels":{"aa":"OPG199: D95N"}},"children":[{"name":"OP382492","node_attrs":{"div":65,"accession":"OP382492","author":{"author":"Colson,P.","value":"Colson,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"lineage":{"value":"B.1.14"},"strain":{"value":"hMPXV-IHU00015"},"date":{"value":"2022-07-22"},"strain_display":{"value":"France/OP382492/2022-07-22"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G161913A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196856-","A196857-","A196858-"]}}},{"name":"OP494266","node_attrs":{"div":64,"accession":"OP494266","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/ON/RKI320"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP494266/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T607-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OP605553","node_attrs":{"div":64,"accession":"OP605553","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"lineage":{"value":"B.1.14"},"strain":{"value":"Slovenia-MPXV-10-2022"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Slovenia/OP605553/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T594A","-608T","-609T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","T196950-","A196951-","A196952-"]}}},{"name":"OP555644","node_attrs":{"div":66,"accession":"OP555644","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.14"},"strain":{"value":"Monkeypox/PT0573/2022"},"date":{"value":"2022-09-06"},"strain_display":{"value":"Portugal/OP555644/2022-09-06"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T594A","-608T","-609T","C93713T","G158549A","-196616T"]}}},{"name":"OP555575","node_attrs":{"div":64,"accession":"OP555575","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.14"},"strain":{"value":"Monkeypox/PT0501/2022"},"date":{"value":"2022-08-16"},"strain_display":{"value":"Portugal/OP555575/2022-08-16"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000101","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["G34308A"],"OPG053":["S128L"]},"labels":{"aa":"OPG053: S128L","clade":"B.1.4"}},"children":[{"name":"OP390177","node_attrs":{"div":63,"accession":"OP390177","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"lineage":{"value":"B.1.4"},"strain":{"value":"ATL-UNIMOL-MPX-292896-L"},"date":{"value":"2022-08-13"},"strain_display":{"value":"Colombia/OP390177/2022-08-13"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C176447T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"NODE_0000102","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["T85846C"],"OPG107":["M112T"]},"labels":{"aa":"OPG107: M112T"}},"children":[{"name":"ON880519","node_attrs":{"div":63,"accession":"ON880519","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-2833/2022"},"date":{"value":"2022-05-13"},"strain_display":{"value":"Canada/ON880519/2022-05-13"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"ON880532","node_attrs":{"div":63,"accession":"ON880532","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-3253/2022"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Canada/ON880532/2022-05-30"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C133187-","A133188-","T133189-","T133190-","T133191-","C133192-","A133193-"]}}}]},{"name":"NODE_0000103","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["C10672T","G112481A","G163626A"],"OPG022":["E63K"]},"labels":{"aa":"OPG022: E63K"}},"children":[{"name":"OR126132","node_attrs":{"div":69,"accession":"OR126132","author":{"author":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C.","value":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Spain"},"clade_membership":{"value":"IIb"},"institution":{"value":"Hospital Ramon y Cajal, Microbiology"},"lineage":{"value":"B.1.4"},"strain":{"value":"HRYC_MPXV002"},"date":{"value":"2023-03-23"},"strain_display":{"value":"Spain/OR126132/2023-03-23"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G6376A","G11924A","G21674A","A87705G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C190834T"],"OPG016":["S142L"],"OPG023":["S326L"],"OPG037":["L254F"]},"labels":{"aa":"OPG016: S142L; OPG023: S326L; OPG037: L254F"}}},{"name":"NODE_0000104","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["G144478A"]}},"children":[{"name":"ON880511","node_attrs":{"div":66,"accession":"ON880511","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-3214/2022"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Canada/ON880511/2022-05-30"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP484341","node_attrs":{"div":69,"accession":"OP484341","author":{"author":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T.","value":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPXV22/human/USA-OK-180"},"date":{"value":"2022-08-17"},"strain_display":{"value":"USA/OP484341/2022-08-17"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G84534A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G175117A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G185991A","-196615A","-196616A","-196617A"],"OPG105":["D1137N"],"OPG204":["D196N"],"OPG210":["D1546N"]},"labels":{"aa":"OPG105: D1137N; OPG204: D196N; OPG210: D1546N"}}}]}]},{"name":"NODE_0000105","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["C24995T","G85774A","G148427A","G189258A"],"OPG040":["D162N"],"OPG107":["R88K"]},"labels":{"aa":"OPG040: D162N; OPG107: R88K"}},"children":[{"name":"ON983163","node_attrs":{"div":66,"accession":"ON983163","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-3532/2022"},"date":{"value":"2022-06-07"},"strain_display":{"value":"Canada/ON983163/2022-06-07"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"ON880515","node_attrs":{"div":66,"accession":"ON880515","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-3467/2022"},"date":{"value":"2022-06-02"},"strain_display":{"value":"Canada/ON880515/2022-06-02"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP415246","node_attrs":{"div":68,"accession":"OP415246","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPX_J6xzTO_9000286"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415246/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G45236A","G174962A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG204":["R144K"]},"labels":{"aa":"OPG204: R144K"}}},{"name":"NODE_0000106","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["C13331T","G67225A"],"OPG085":["S436L"]},"labels":{"aa":"OPG085: S436L"}},"children":[{"name":"OP279037","node_attrs":{"div":68,"accession":"OP279037","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-4113/2022"},"date":{"value":"2022-07-04"},"strain_display":{"value":"Canada/OP279037/2022-07-04"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OR759177","node_attrs":{"div":72,"accession":"OR759177","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.4"},"strain":{"value":"hMpxV/Canada/ON-PHOL089/2022"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759177/2022-09-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","G62952A","G100442A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G178818A","C181598T","-196615A"]}}},{"name":"OR759161","node_attrs":{"div":68,"accession":"OR759161","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.4"},"strain":{"value":"hMpxV/Canada/ON-PHOL073/2022"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759161/2022-08-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}}]}]},{"name":"NODE_0000107","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["G36259A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G174543A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}},"children":[{"name":"OP626135","node_attrs":{"div":67,"accession":"OP626135","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPXV/Germany/2022/RKI496"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP626135/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C40251T","C154472T","G167517A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"],"OPG058":["D62N"],"OPG181":["H21Y"],"OPG193":["E62K"]},"labels":{"aa":"OPG058: D62N; OPG181: H21Y; OPG193: E62K"}}},{"name":"OP863227","node_attrs":{"div":64,"accession":"OP863227","author":{"author":"Haw,M.,Probert,W.,Espinosa,A.,Kath,C.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Haw,M.,Probert,W.,Espinosa,A.,Kath,C.,O'Neil,R.,Bell,J.,Hacker,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDPH, VRDL"},"lineage":{"value":"B.1.4"},"strain":{"value":"hMpxV/USA/CA-CDPH-000052/2022"},"date":{"value":"2022-07-21"},"strain_display":{"value":"USA/OP863227/2022-07-21"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OQ547876","node_attrs":{"div":64,"accession":"OQ547876","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDPH, VRDL"},"lineage":{"value":"B.1.4"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000164/2022"},"date":{"value":"2022-06-28"},"strain_display":{"value":"USA/OQ547876/2022-06-28"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C699-","T700-","T701-","T6976-","C196727-","T196728-","T196729-"]}}},{"name":"NODE_0000108","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["-607T","C177720T","-196615A"],"OPG205":["R689C"]},"labels":{"aa":"OPG205: R689C"}},"children":[{"name":"OQ547900","node_attrs":{"div":66,"accession":"OQ547900","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDPH, VRDL"},"lineage":{"value":"B.1.4"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000185/2022"},"date":{"value":"2022-12-21"},"strain_display":{"value":"USA/OQ547900/2022-12-21"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T6976-","G92733A"],"OPG113":["E335K"]},"labels":{"aa":"OPG113: E335K"}}},{"name":"OQ503748","node_attrs":{"div":67,"accession":"OQ503748","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/USA/WA-UW-108160/2022"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ503748/2022-10-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A80755C","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G159203A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG104":["C89G"],"OPG185":["G96E"]},"labels":{"aa":"OPG104: C89G; OPG185: G96E"}}}]},{"name":"NODE_0000109","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["C25967T"],"OPG042":["W377*"]},"labels":{"aa":"OPG042: W377*"}},"children":[{"name":"OQ503808","node_attrs":{"div":73,"accession":"OQ503808","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00434/2022"},"date":{"value":"2022-09-28"},"strain_display":{"value":"USA/OQ503808/2022-09-28"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G70435A","C125412T","C141442T","C141511T","G158709A","A163469T","G175698A","G176439A","A196814-","A196815-","A196816-"],"OPG145":["S489L"],"OPG161":["S114L","S137F"],"OPG189":["E46V"],"OPG205":["D15N","D262N"]},"labels":{"aa":"OPG145: S489L; OPG161: S114L, S137F; OPG189: E46V; OPG205: D15N, D262N"}}},{"name":"OQ644775","node_attrs":{"div":69,"accession":"OQ644775","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00469/2022"},"date":{"value":"2022-11-18"},"strain_display":{"value":"USA/OQ644775/2022-11-18"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C97805T","C100640T","C105632T","C172792T","T196673-","G196674-"],"OPG117":["P586L"],"OPG124":["E113K"]},"labels":{"aa":"OPG117: P586L; OPG124: E113K"}}}]}]}]},{"name":"NODE_0000110","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["G5595A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C191615T"],"OPG015":["Q188*"],"OPG015_dup":["Q188*"]},"labels":{"aa":"OPG015: Q188*; OPG015_dup: Q188*","clade":"B.1.8"}},"children":[{"name":"OP215224","node_attrs":{"div":62,"accession":"OP215224","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/RKI235"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP215224/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP722502","node_attrs":{"div":64,"accession":"OP722502","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00243/2022"},"date":{"value":"2022-07-20"},"strain_display":{"value":"USA/OP722502/2022-07-20"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T731-","G732-","C733-","G53326A","G67898A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG085":["P212S"]},"labels":{"aa":"OPG085: P212S"}}},{"name":"NODE_0000111","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["G78034A","C80111T"],"OPG099":["D124N"]},"labels":{"aa":"OPG099: D124N"}},"children":[{"name":"ON622718","node_attrs":{"div":65,"accession":"ON622718","author":{"author":"Martinez-Puchol,S.,Coello,A.,Bordoy,A.E.,Soler,L.,Panisello,D.,Gonzalez-Gomez,S.,Clara,G.,Paris de Leon,A.,Not,A.,Hernandez,A.,Bofill-Mas,S.,Saludes,V.,Blanco,I.,Martro,E.,Cardona,P.-J.","value":"Martinez-Puchol,S.,Coello,A.,Bordoy,A.E.,Soler,L.,Panisello,D.,Gonzalez-Gomez,S.,Clara,G.,Paris de Leon,A.,Not,A.,Hernandez,A.,Bofill-Mas,S.,Saludes,V.,Blanco,I.,Martro,E.,Cardona,P.-J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Spain"},"clade_membership":{"value":"IIb"},"institution":{"value":"Microbiology, Hospital Universitari Germans Trias i Pujol, Spain"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/ES0001/HUGTiP/2022"},"date":{"value":"2022-05-20"},"strain_display":{"value":"Spain/ON622718/2022-05-20"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C14113-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T139150C","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","-196615A","-196616A"],"OPG156":["Q87R"]},"labels":{"aa":"OPG156: Q87R"}}},{"name":"NODE_0000112","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["G22643A","G63811A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"],"OPG038":["H173Y"]},"labels":{"aa":"OPG038: H173Y"}},"children":[{"name":"OP303781","node_attrs":{"div":66,"accession":"OP303781","author":{"author":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV_USA_2022_FL0018"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP303781/2022-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP415254","node_attrs":{"div":68,"accession":"OP415254","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPX_imBNaw_9000300"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415254/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T119985C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G189258A"]}}},{"name":"OP480416","node_attrs":{"div":72,"accession":"OP480416","author":{"author":"Deanhardt,B.,Miller,M.,Wang,J.R.","value":"Deanhardt,B.,Miller,M.,Wang,J.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of North Carolina at Chapel Hill, Department of Genetics"},"lineage":{"value":"B.1.8"},"strain":{"value":"hMPXV/USA/NC-UNC-0017/2022"},"date":{"value":"2022-08-24"},"strain_display":{"value":"USA/OP480416/2022-08-24"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G2079A","C12359T","A31053G","C89240T","G150404A","C173533A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C195131T"],"OPG002":["R225C"],"OPG002_dup":["R225C"],"OPG023":["R181Q"],"OPG047":["C48R"],"OPG109":["D70N"],"OPG176":["R199K"]},"labels":{"aa":"OPG002: R225C; OPG002_dup: R225C; OPG023: R181Q; OPG047: C48R; OPG109: D70N; OPG176: R199K"}}},{"name":"OP459214","node_attrs":{"div":66,"accession":"OP459214","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"lineage":{"value":"B.1.8"},"strain":{"value":"ANT-LDSP-ANT-MPX-23631-L"},"date":{"value":"2022-08-30"},"strain_display":{"value":"Colombia/OP459214/2022-08-30"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP642374","node_attrs":{"div":67,"accession":"OP642374","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.8"},"strain":{"value":"ANT-LDSP-ANT-MPX-24722-L"},"date":{"value":"2022-09-08"},"strain_display":{"value":"Colombia/OP642374/2022-09-08"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G168759A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG195":["R177K"]},"labels":{"aa":"OPG195: R177K"}}},{"name":"OQ320513","node_attrs":{"div":70,"accession":"OQ320513","author":{"author":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y.","value":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV_USA_2022_FL0009"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ320513/2022-10-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G4038A","A39081T","C67289T","G73790A","T133102-","A173284-","T173285-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C193172T"],"OPG057":["I372N"],"OPG085":["E415K"],"OPG094":["G4E"]},"labels":{"aa":"OPG057: I372N; OPG085: E415K; OPG094: G4E"}}},{"name":"OQ721938","node_attrs":{"div":68,"accession":"OQ721938","author":{"author":"Gigante,C.,Epie,N.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Perez,T.,Li,Y.","value":"Gigante,C.,Epie,N.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Perez,T.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV_USA_2022_SC0010"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721938/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C96649T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","G188382A"],"OPG117":["H201Y"]},"labels":{"aa":"OPG117: H201Y"}}},{"name":"OR759149","node_attrs":{"div":70,"accession":"OR759149","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.8"},"strain":{"value":"hMpxV/Canada/ON-PHOL055/2022"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759149/2022-08-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C8555T","G95862A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168089T","G181674A","-196615A"],"OPG116":["A168T"],"OPG210":["E107K"]},"labels":{"aa":"OPG116: A168T; OPG210: E107K"}}}]}]},{"name":"NODE_0000113","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","A150591-","T150592-","A150595-","T150596-","A150597-","T150598-","A150600-","T150601-","G161296A","-179172C","-179181C","C196308T"],"OPG001_dup":["S225L"]},"labels":{"aa":"OPG001_dup: S225L"}},"children":[{"name":"OP331337","node_attrs":{"div":63,"accession":"OP331337","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV_UK_2022_9000183"},"date":{"value":"2022-06-29"},"strain_display":{"value":"United Kingdom/OP331337/2022-06-29"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G902A","G150590-","G150593-","G150594-","G150599-","G150602-","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG001":["S225L"]},"labels":{"aa":"OPG001: S225L"}}},{"name":"OP615338","node_attrs":{"div":66,"accession":"OP615338","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/ON/RKI459"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP615338/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G89716A","G128858A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","C186220T"],"OPG110":["E29K"],"OPG210":["A1622V"]},"labels":{"aa":"OPG110: E29K; OPG210: A1622V"}}},{"name":"OP626130","node_attrs":{"div":64,"accession":"OP626130","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/RKI492"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OP626130/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C24929T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C179172-","C179181-","T196308C"],"OPG001_dup":["L225S"],"OPG040":["D184N"]},"labels":{"aa":"OPG001_dup: L225S; OPG040: D184N"}}},{"name":"OP555609","node_attrs":{"div":65,"accession":"OP555609","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.8"},"strain":{"value":"Monkeypox/PT0538/2022"},"date":{"value":"2022-08-23"},"strain_display":{"value":"Portugal/OP555609/2022-08-23"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","G902A","C25269T","G25692A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C179172-","C179181-"],"OPG001":["S225L"]},"labels":{"aa":"OPG001: S225L"}}},{"name":"OP894040","node_attrs":{"div":68,"accession":"OP894040","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/ON/RKI620"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP894040/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G2039A","G34298T","C37048T","G70190A","G150590-","G150593-","G150594-","G150599-","G150602-","G153094A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"],"OPG002":["S238L"],"OPG089":["E109K"],"OPG180":["D135N"]},"labels":{"aa":"OPG002: S238L; OPG089: E109K; OPG180: D135N"}}},{"name":"OR030928","node_attrs":{"div":64,"accession":"OR030928","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/UZ_REGA_17"},"date":{"value":"2022-07-19"},"strain_display":{"value":"Belgium/OR030928/2022-07-19"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G902A","C68981T","G150590-","G150593-","G150594-","G150599-","G150602-","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG001":["S225L"],"OPG087":["S42L"]},"labels":{"aa":"OPG001: S225L; OPG087: S42L"}}},{"name":"OR449682","node_attrs":{"div":63,"accession":"OR449682","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/ON/RKI968"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449682/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"NODE_0000114","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["C80545T","G102614A","G150590-","G150593-","G150594-","G150599-","G150602-","C170573T","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG103":["S182L"],"OPG122":["V63I"],"OPG198":["S179L"]},"labels":{"aa":"OPG103: S182L; OPG122: V63I; OPG198: S179L"}},"children":[{"name":"OR035714","node_attrs":{"div":66,"accession":"OR035714","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/UZ_REGA_108"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035714/2022-10-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OR095062","node_attrs":{"div":67,"accession":"OR095062","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/UZ_REGA_244/Belgium/2022"},"date":{"value":"2022-08-16"},"strain_display":{"value":"Belgium/OR095062/2022-08-16"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C62305T"]}}}]}]}]},{"name":"NODE_0000121","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["C89906T","G94798A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG110":["S92F"],"OPG115":["E47K"]},"labels":{"aa":"OPG110: S92F; OPG115: E47K","clade":"B.1.10"}},"children":[{"name":"ON720848","node_attrs":{"div":64,"accession":"ON720848","author":{"author":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Spain"},"clade_membership":{"value":"IIb"},"institution":{"value":"Microbial Genomics, Hospital General Universitario Gregorio Marañón, Madrid, Spain"},"lineage":{"value":"B.1.10"},"strain":{"value":"MpxV/Spain/MD-HGUGM-6513479/2022"},"date":{"value":"2022-05-27"},"strain_display":{"value":"Spain/ON720848/2022-05-27"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A327-","T605-","T606-","A1697-","T4296-","T6587-","T6588-","T7253-","G7724-","T8017-","A8036-","T8499-","T9514-","A9869-","T10502-","A10914-","T11188-","C11749-","T11761-","T12121-","A15754-","A17087-","T18866-","A19360-","T20663-","A21081-","T21975-","T24678-","T25853-","T26099-","C27002-","A27114-","C27799-","A28529-","A28530-","T32194-","T33414-","G35949-","T37982-","T39131-","T39866-","T41744-","T42990-","C43014-","G43200-","A43443-","T44120-","T44738-","G46762-","T48675-","A49134-","G49833-","A51022-","A52765-","A54968-","A55124-","T55560-","T56040-","T57075-","A57277-","A58650-","T61749-","A62041-","T63628-","A64728-","A64935-","A65535-","A65967-","T66783-","A66843-","A67164-","C68466-","T68481-","C68899-","G69145-","A69744-","T69768-","A71254-","G71359-","T75833-","A76072-","T76084-","T76085-","A76153-","A76154-","A76890-","A77260-","T77803-","T78062-","A79042-","A79181-","G79217-","C79533T","A79787-","G80950-","C82482-","T84846-","T88095-","T88836-","T88941-","A89106-","T90646-","T91129-","T91370-","A91583-","A91705-","T94795-","A95341-","A95574-","G95742-","G95818-","A97351-","A97480-","A97501-","A97699-","A98683-","T101452-","G101515-","T102437-","T103367-","T103368-","T104279-","T105360-","T106596-","T108598-","A113921-","T113951-","C114431-","T114518-","T114755-","T115127-","G115801-","A116014-","C116494-","T116963-","T121121-","T121122-","G121269-","C121546-","T124022-","T124751-","A125249-","A126568-","T126682-","A126715-","A127250-","A127754-","A132023-","A132024-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133639-","T136780-","T137886-","A143045-","G143363-","T143478-","A144230-","T146131-","A148000-","A149727-","A150340-","T150538-","T150539-","A150635-","T150864-","A151490-","A151508-","G151545-","A152676-","T152686-","A153358-","A153424-","A153517-","T154862-","T155424-","C156607-","C156608-","A157997-","T163498-","T163597-","A163957-","A165461-","A166740-","G167640-","A167967-","T168120-","A170728-","T170758-","T170903-","T170904-","T172087-","T172667-","G179036-","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A179551-","A179950-","T180905-","G181052-","A181253-","C183534-","A183780-","T187080-","A190935-","A191015-","G191519-","A196613-","A196614-","T196888-","T197183-"],"OPG015_dup":["G156-"],"OPG016":["T176-"],"OPG019":["G49-"],"OPG021":["N95-"],"OPG023":["G385-"],"OPG043":["G53-"],"OPG044":["K147-"],"OPG066":["P223-"],"OPG068":["L159-","D545-"],"OPG070":["N145-"],"OPG074":["K523-"],"OPG084":["K3-","K272-","R416-"],"OPG085":["F457-"],"OPG087":["L15-","G97-"],"OPG090":["K26-"],"OPG096":["L83-"],"OPG098":["S121-"],"OPG099":["F47-"],"OPG100":["F19-"],"OPG102":["K33-"],"OPG104":["P24-"],"OPG109":["K206-"],"OPG111":["F128-"],"OPG112":["S42-"],"OPG115":["S46-"],"OPG116":["K72-"],"OPG117":["K435-","N478-","R551-"],"OPG118":["I80-"],"OPG122":["Y4-"],"OPG123":["K569-"],"OPG133":["K394-"],"OPG134":["E18-","P249-"],"OPG139":["P34-"],"OPG145":["F26-","F269-","K435-"],"OPG148":["I195-","F233-"],"OPG149":["K19-"],"OPG151":["K1034-"],"OPG164":["R90-"],"OPG165":["M239-"],"OPG172":["I192-"],"OPG175":["N96-"],"OPG176":["K178-"],"OPG178":["D13-"],"OPG180":["K223-","K276-"],"OPG181":["F151-"],"OPG189":["L56-","K209-"],"OPG190":["N114-"],"OPG192":["K4-"],"OPG193":["G103-","F263-"],"OPG198":["K231-"],"OPG208":["I96-"],"OPG209":["L130-"],"OPG210":["P727-"]},"labels":{"aa":"OPG015_dup: G156-; OPG016: T176-; OPG019: G49-; OPG021: N95-; OPG023: G385-; OPG043: G53-; OPG044: K147-; OPG066: P223-; OPG068: L159-, D545-; OPG070: N145-; OPG074: K523-; OPG084: K3-, K272-, R416-; OPG085: F457-; OPG087: L15-, G97-; OPG090: K26-; OPG096: L83-; OPG098: S121-; OPG099: F47-; OPG100: F19-; OPG102: K33-; OPG104: P24-; OPG109: K206-; OPG111: F128-; OPG112: S42-; OPG115: S46-; OPG116: K72-; OPG117: K435-, N478-, R551-; OPG118: I80-; OPG122: Y4-; OPG123: K569-; OPG133: K394-; OPG134: E18-, P249-; OPG139: P34-; OPG145: F26-, F269-, K435-; OPG148: I195-, F233-; OPG149: K19-; OPG151: K1034-; OPG164: R90-; OPG165: M239-; OPG172: I192-; OPG175: N96-; OPG176: K178-; OPG178: D13-; OPG180: K223-, K276-; OPG181: F151-; OPG189: L56-, K209-; OPG190: N114-; OPG192: K4-; OPG193: G103-, F263-; OPG198: K231-; OPG208: I96-; OPG209: L130-; OPG210: P727-"}}},{"name":"OP245334","node_attrs":{"div":65,"accession":"OP245334","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPX/PT0081/2022"},"date":{"value":"2022-07-23"},"strain_display":{"value":"Portugal/OP245334/2022-07-23"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-609T","G610-","T611-","C120237T","G126047A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","A196619-","T196620-"],"OPG148":["R21K"]},"labels":{"aa":"OPG148: R21K"}}},{"name":"OP205110","node_attrs":{"div":63,"accession":"OP205110","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV_UK_2022_9000147"},"date":{"value":"2022-06-14"},"strain_display":{"value":"United Kingdom/OP205110/2022-06-14"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP205091","node_attrs":{"div":63,"accession":"OP205091","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV_UK_2022_9000103"},"date":{"value":"2022-06-13"},"strain_display":{"value":"United Kingdom/OP205091/2022-06-13"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP450985","node_attrs":{"div":63,"accession":"OP450985","author":{"author":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y.","value":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV_USA_2022_TX0019"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP450985/2022-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","A136552-","T136553-","C136554-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP484683","node_attrs":{"div":65,"accession":"OP484683","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Germany/2022/RKI362"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP484683/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C17027T","C84943T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-"],"OPG029":["D15N"],"OPG105":["S1273F"]},"labels":{"aa":"OPG029: D15N; OPG105: S1273F"}}},{"name":"OP894038","node_attrs":{"div":64,"accession":"OP894038","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Germany/2022/ON/RKI618"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP894038/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C33964T","T136514-","C136515-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","G181052-"],"OPG052":["R11Q"],"OPG153":["D385-"],"OPG209":["G179-"]},"labels":{"aa":"OPG052: R11Q; OPG153: D385-; OPG209: G179-"}}},{"name":"OQ773504","node_attrs":{"div":65,"accession":"OQ773504","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Germany/2022/ON/RKI885"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773504/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C33103T","A41660-","A41661-","T41662-","T41663-","T41664-","G41665-","T41666-","T41667-","T41668-","T41669-","A41670-","C41671-","T41672-","C41673-","T41674-","A41675-","T41676-","A41677-","C45605T","G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG049":["E17K"],"OPG061":["Y70-","R71-","V72-","K73-","Q74-","I75-"]},"labels":{"aa":"OPG049: E17K; OPG061: Y70-, R71-, V72-, K73-, Q74-, I75-"}}},{"name":"OQ581847","node_attrs":{"div":76,"accession":"OQ581847","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Spain"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0005b/2022"},"date":{"value":"2022-07-01"},"strain_display":{"value":"Spain/OQ581847/2022-07-01"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A43453G","A66769C","T88735A","G90070A","C101656T","G104325A","C121681T","G127869A","G132490A","T133095A","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T139779C","G140866T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C151204T","T176743A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG063":["L79P"],"OPG085":["V588G"],"OPG109":["E238V"],"OPG110":["D147N"],"OPG123":["A249V"],"OPG150":["G31R"],"OPG160":["S70Y"],"OPG205":["L363*"]},"labels":{"aa":"OPG063: L79P; OPG085: V588G; OPG109: E238V; OPG110: D147N; OPG123: A249V; OPG150: G31R; OPG160: S70Y; OPG205: L363*"}}},{"name":"OR264420","node_attrs":{"div":64,"accession":"OR264420","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.10"},"strain":{"value":"45_B"},"date":{"value":"2022-07-10"},"strain_display":{"value":"Australia/OR264420/2022-07-10"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G63147A","-179218A","-179219T","-179220T"]}}},{"name":"NODE_0000122","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C150831T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-"]}},"children":[{"name":"ON959143","node_attrs":{"div":65,"accession":"ON959143","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Finland"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPX-96/Finland/2022"},"date":{"value":"2022-06-16"},"strain_display":{"value":"Finland/ON959143/2022-06-16"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188491T"]}}},{"name":"OP382489","node_attrs":{"div":65,"accession":"OP382489","author":{"author":"Colson,P.","value":"Colson,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"lineage":{"value":"B.1.10"},"strain":{"value":"hMPXV-IHU00012"},"date":{"value":"2022-07-19"},"strain_display":{"value":"France/OP382489/2022-07-19"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G109437A","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G150603-","A150604-","T150605-","A150606-","T150607-","G150608-","A150609-","T150610-","G150611-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG129":["S523L"],"OPG153":["D384-","D385-"]},"labels":{"aa":"OPG129: S523L; OPG153: D384-, D385-"}}},{"name":"OP879740","node_attrs":{"div":64,"accession":"OP879740","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"lineage":{"value":"B.1.10"},"strain":{"value":"NJ-MPXV-022"},"date":{"value":"2022-07-06"},"strain_display":{"value":"USA/OP879740/2022-07-06"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-"]}}}]},{"name":"NODE_0000123","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["C20879T","C60094T"],"OPG036":["M62I"],"OPG080":["R642K"]},"labels":{"aa":"OPG036: M62I; OPG080: R642K"}},"children":[{"name":"OP415264","node_attrs":{"div":66,"accession":"OP415264","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPX_Tga3e9_9000325"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415264/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G86904A","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035722","node_attrs":{"div":66,"accession":"OR035722","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/UZ_REGA_116"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035722/2022-10-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G149818A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG176":["D4N"]},"labels":{"aa":"OPG176: D4N"}}},{"name":"OR464201","node_attrs":{"div":65,"accession":"OR464201","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV_USA_2022_NY0053"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OR464201/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-"]}}}]},{"name":"NODE_0000124","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["G50672A","C179265-","A179266-","T179267-"],"OPG070":["R28K"]},"labels":{"aa":"OPG070: R28K"}},"children":[{"name":"OP642387","node_attrs":{"div":64,"accession":"OP642387","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.10"},"strain":{"value":"ANT-LDSP-ANT-MPX-24914-L"},"date":{"value":"2022-09-09"},"strain_display":{"value":"Colombia/OP642387/2022-09-09"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP689664","node_attrs":{"div":66,"accession":"OP689664","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Germany/2022/ON/RKI511"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"Germany/OP689664/2022-10-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C13624T","C43472T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG063":["E73K"]},"labels":{"aa":"OPG063: E73K"}}},{"name":"OQ696103","node_attrs":{"div":69,"accession":"OQ696103","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.10"},"strain":{"value":"ANT-LDSP-ANT-MPX-31501C"},"date":{"value":"2022-11-22"},"strain_display":{"value":"Colombia/OQ696103/2022-11-22"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G32863A","G45416A","C72770T","C123118T","C148771T","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG092":["E60K"],"OPG174":["D209N"]},"labels":{"aa":"OPG092: E60K; OPG174: D209N"}}},{"name":"NODE_0000125","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["C49265T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-179265C","-179266A","-179267T"]}},"children":[{"name":"OP536764","node_attrs":{"div":66,"accession":"OP536764","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.10"},"strain":{"value":"9000385"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536764/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","C100007T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"],"OPG118":["S521F"]},"labels":{"aa":"OPG118: S521F"}}},{"name":"OP459218","node_attrs":{"div":65,"accession":"OP459218","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"lineage":{"value":"B.1.10"},"strain":{"value":"ANT-LDSP-ANT-MPX-23655-L"},"date":{"value":"2022-08-30"},"strain_display":{"value":"Colombia/OP459218/2022-08-30"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP819958","node_attrs":{"div":65,"accession":"OP819958","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.10"},"strain":{"value":"QUI_INS_MPX_0967_L"},"date":{"value":"2022-10-15"},"strain_display":{"value":"Colombia/OP819958/2022-10-15"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150603-","A150604-","T150605-","A150606-","T150607-","G150608-","A150609-","T150610-","G150611-"]}}}]}]}]},{"name":"OQ773485_NODE_0000126_merged","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["C182950T"],"OPG210":["S532L"]},"labels":{"aa":"OPG210: S532L","clade":"B.1.12"}},"children":[{"name":"OQ773485","node_attrs":{"div":62,"accession":"OQ773485","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV/Germany/2022/ON/RKI866"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773485/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G1302A","G150551-","A150563-","T150564-","G150565-","A150566-","T150567-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179189A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"],"OPG001":["L92F"]},"labels":{"aa":"OPG001: L92F"}}},{"name":"OP539926","node_attrs":{"div":67,"accession":"OP539926","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00141/2022"},"date":{"value":"2022-08-25"},"strain_display":{"value":"USA/OP539926/2022-08-25"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C23759T","G55059A","C84767T","G102972A","G144497A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A190409-","A190410-","T190411-","G190412-","G190413-","A190414-","T190415-","T190416-","C190417-","G190418-","C190419-","G190420-","T190421-","A190422-","T190423-","A190424-","G190425-","C190426-","T190427-","A190428-","T190429-","T190430-","T190431-","A190432-","C190433-","G190434-","T190435-","A190436-","T190437-","T190438-","A190439-","G190440-","T190441-","A190442-","T190443-","C190444-","G190445-","G190446-","C190447-","A190448-","T190449-","C190450-","T190451-","C190452-","T190453-","T190454-","T190455-","T190456-","G190457-","T190458-","A190459-","T190460-","C190461-","T190462-","T190463-","G190464-","T190465-","T190466-","A190467-","A190468-","T190469-","T190470-","G190471-","T190472-","C190473-","A190474-","C190475-","A190476-","A190477-","A190478-","C190479-","T190480-","A190481-","G190482-","T190483-","A190484-","C190485-","A190486-","T190487-","T190488-","A190489-","C190490-","T190491-","T190492-","C190493-","A190494-","A190495-","T190496-","C190497-","T190498-","G190499-","A190500-","A190501-","A190502-","A190503-","T190504-","A190505-"],"OPG073":["S28L"],"OPG122":["R182Q"],"OPG166":["E34K"]},"labels":{"aa":"OPG073: S28L; OPG122: R182Q; OPG166: E34K"}}},{"name":"OP605580","node_attrs":{"div":63,"accession":"OP605580","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"lineage":{"value":"B.1.12"},"strain":{"value":"Slovenia-MPXV-39-2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Slovenia/OP605580/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","C179082T","C179091T","T179094A","C179100T","T179103A","C179109T","T179112A","C179118T","T179121A","C179127T","T179130A","C179136T","C179145T","T179148A","C179154T","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179239A","-179240T","-179241A","-179242T","-179243A","G189288A"]}}},{"name":"OP605566","node_attrs":{"div":63,"accession":"OP605566","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"lineage":{"value":"B.1.12"},"strain":{"value":"Slovenia-MPXV-24-2022"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Slovenia/OP605566/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","C167944T","G196973-","A196974-","A196975-"],"OPG193":["S204L"]},"labels":{"aa":"OPG193: S204L"}}},{"name":"NODE_0000127","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G1302A","G78328A","C195908T"],"OPG001":["L92F"],"OPG001_dup":["L92F"]},"labels":{"aa":"OPG001: L92F; OPG001_dup: L92F"}},"children":[{"name":"OP524001","node_attrs":{"div":63,"accession":"OP524001","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV/Germany/2022/RKI399"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP524001/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000128","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["C57550T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP415206","node_attrs":{"div":64,"accession":"OP415206","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPX_BhVKjm_9000232"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415206/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP415207","node_attrs":{"div":64,"accession":"OP415207","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPX_BhVKjm_9000233"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415207/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000129","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G111084A"]}},"children":[{"name":"OP013003","node_attrs":{"div":63,"accession":"OP013003","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.12"},"strain":{"value":"MpxV/human/CAN/UN-NML-3276/2022"},"date":{"value":"2022-05-31"},"strain_display":{"value":"Canada/OP013003/2022-05-31"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"ON880548","node_attrs":{"div":63,"accession":"ON880548","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.12"},"strain":{"value":"MpxV/human/CAN/UN-NML-3448/2022"},"date":{"value":"2022-06-03"},"strain_display":{"value":"Canada/ON880548/2022-06-03"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000130","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G121510A"]}},"children":[{"name":"ON880540","node_attrs":{"div":64,"accession":"ON880540","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.12"},"strain":{"value":"MpxV/human/CAN/UN-NML-3342/2022"},"date":{"value":"2022-06-01"},"strain_display":{"value":"Canada/ON880540/2022-06-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OR759170","node_attrs":{"div":69,"accession":"OR759170","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.12"},"strain":{"value":"hMpxV/Canada/ON-PHOL082/2022"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759170/2022-08-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","G10060A","G37022A","C132410T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G154793A","C180055T","-196615A"],"OPG055":["S21F"],"OPG181":["D128N"]},"labels":{"aa":"OPG055: S21F; OPG181: D128N"}}}]},{"name":"NODE_0000131","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G98233A","G98455A","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG117":["D729N"],"OPG118":["G4K"]},"labels":{"aa":"OPG117: D729N; OPG118: G4K"}},"children":[{"name":"ON880413","node_attrs":{"div":66,"accession":"ON880413","author":{"author":"Coletti,T.M.,Ghilardi,F.,khan,M.J.,Claro,I.M.,Valenca,I.N.,Faria,N.R.,Sabino,E.C.","value":"Coletti,T.M.,Ghilardi,F.,khan,M.J.,Claro,I.M.,Valenca,I.N.,Faria,N.R.,Sabino,E.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Brazil"},"clade_membership":{"value":"IIb"},"institution":{"value":"Imperial College London, School of Public Health"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPX/BR0002/2022"},"date":{"value":"2022-06-14"},"strain_display":{"value":"Brazil/ON880413/2022-06-14"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C76334T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG097":["R181K"]},"labels":{"aa":"OPG097: R181K"}}},{"name":"NODE_0000132","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G98456A","-179172C","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C"]}},"children":[{"name":"OP171920","node_attrs":{"div":68,"accession":"OP171920","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV22/human/USA-NE-31"},"date":{"value":"2022-07-04"},"strain_display":{"value":"USA/OP171920/2022-07-04"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G102694A","G160484A","-179173A","-179174T","-179175T","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"OP303780","node_attrs":{"div":66,"accession":"OP303780","author":{"author":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV_USA_2022_FL0017"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP303780/2022-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"]}}},{"name":"OP270022","node_attrs":{"div":69,"accession":"OP270022","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.12"},"strain":{"value":"MpxV/human/CAN/UN-NML-3972/2022"},"date":{"value":"2022-07-04"},"strain_display":{"value":"Canada/OP270022/2022-07-04"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","G3361A","C152970T","-179173A","-179174T","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G181349A","C193849T"],"OPG003":["S416L"],"OPG003_dup":["S416L"]},"labels":{"aa":"OPG003: S416L; OPG003_dup: S416L"}}},{"name":"OQ626770","node_attrs":{"div":69,"accession":"OQ626770","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV22/human/USA-NE-324"},"date":{"value":"2022-09-29"},"strain_display":{"value":"USA/OQ626770/2022-09-29"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C3438T","C10484T","A61974G","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G193772A","-196615A","-196616A","-196617A"]}}},{"name":"OR209309","node_attrs":{"div":69,"accession":"OR209309","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV_USA_2022_TN0019"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR209309/2022-12-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C93601T","C94418T","T133101-","T133102-","C136029T","-179173A","-179174T","-179175T","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["A624V"],"OPG114":["E84K"]},"labels":{"aa":"OPG113: A624V; OPG114: E84K"}}},{"name":"NODE_0000133","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G153910A","C179199-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"],"OPG180":["E407K"]},"labels":{"aa":"OPG180: E407K"}},"children":[{"name":"OQ427114","node_attrs":{"div":68,"accession":"OQ427114","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV_USA_2022_NY0039"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ427114/2022-10-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G71407A","-179173A","-179174T","-179175T","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-196615A"],"OPG091":["R13K"]},"labels":{"aa":"OPG091: R13K"}}},{"name":"OQ918701","node_attrs":{"div":72,"accession":"OQ918701","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00490/2023"},"date":{"value":"2023-02-10"},"strain_display":{"value":"USA/OQ918701/2023-02-10"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C21910T","G28483A","G39552A","A57421-","C57422-","A57423-","A57424-","A57425-","A57426-","A57427-","G57428-","G57429-","A57430-","C57431-","A57432-","T57433-","G57434-","T57435-","A57436-","A57437-","A57438-","C57439-","T57440-","T57441-","G132490A","C150443T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG037":["R175K"],"OPG057":["S215F"],"OPG075":["K20-","F21-","T22-","C23-","P24-","F25-","C26-"],"OPG176":["T212I"]},"labels":{"aa":"OPG037: R175K; OPG057: S215F; OPG075: K20-, F21-, T22-, C23-, P24-, F25-, C26-; OPG176: T212I"}}},{"name":"OR759180","node_attrs":{"div":71,"accession":"OR759180","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.12"},"strain":{"value":"hMpxV/Canada/ON-PHOL092/2022"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759180/2022-09-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","C16209T","C24208T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","G182088A","G182189A","A196614-"],"OPG027":["E57K"],"OPG210":["E245K"]},"labels":{"aa":"OPG027: E57K; OPG210: E245K"}}},{"name":"OR464203","node_attrs":{"div":69,"accession":"OR464203","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV_USA_2022_NY0055"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OR464203/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T3777C","C119854T","-179173A","-179174T","-179175T","C179181-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","A193433G"],"OPG137":["H85Y"]},"labels":{"aa":"OPG137: H85Y"}}}]},{"name":"NODE_0000134","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["C24231T","-179173A","-179174T","-179175T","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T"]}},"children":[{"name":"OR095033","node_attrs":{"div":68,"accession":"OR095033","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV/UZ_REGA_215/Belgium/2022"},"date":{"value":"2022-08-08"},"strain_display":{"value":"Belgium/OR095033/2022-08-08"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G61102A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG080":["S306F"]},"labels":{"aa":"OPG080: S306F"}}},{"name":"NODE_0000135","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G23457A"],"OPG039":["S221F"]},"labels":{"aa":"OPG039: S221F"}},"children":[{"name":"OP415236","node_attrs":{"div":68,"accession":"OP415236","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPX_ilzdZn_9000269"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415236/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A190409-","A190410-","T190411-","G190412-","G190413-","A190414-","T190415-","T190416-","C190417-","G190418-","C190419-","G190420-","T190421-","A190422-","T190423-","A190424-","G190425-","C190426-"]}}},{"name":"OR264365","node_attrs":{"div":68,"accession":"OR264365","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.12"},"strain":{"value":"12_A"},"date":{"value":"2022-07-18"},"strain_display":{"value":"Australia/OR264365/2022-07-18"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000136","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G184227A"],"OPG210":["D958N"]},"labels":{"aa":"OPG210: D958N"}},"children":[{"name":"OP390179","node_attrs":{"div":68,"accession":"OP390179","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"lineage":{"value":"B.1.12"},"strain":{"value":"BOL-UNIMOL-MPX-293015-L"},"date":{"value":"2022-08-24"},"strain_display":{"value":"Colombia/OP390179/2022-08-24"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP382485","node_attrs":{"div":68,"accession":"OP382485","author":{"author":"Colson,P.","value":"Colson,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"lineage":{"value":"B.1.12"},"strain":{"value":"hMPXV-IHU00008"},"date":{"value":"2022-07-05"},"strain_display":{"value":"France/OP382485/2022-07-05"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]}]}]}]}]}]},{"name":"NODE_0000050_NODE_0000115_merged","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["C70780T","-150590G","-150593G","-150594G","-150599G","-150602G"]},"labels":{"clade":"B.1.5"}},"children":[{"name":"OP150925","node_attrs":{"div":62,"accession":"OP150925","author":{"author":"Gigante,C.,Xia,D.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y.","value":"Gigante,C.,Xia,D.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV_USA_2022_GA001"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/OP150925/2022-05-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON780017","node_attrs":{"div":62,"accession":"ON780017","author":{"author":"Gramigna,G.,Giombini,E.,Gruber,C.E.M.,Rueca,M.,Carletti,F.,Cicalini,S.,Lapa,D.,Puro,V.,Marani,A.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Rivano Capparuccia,M.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F.","value":"Gramigna,G.,Giombini,E.,Gruber,C.E.M.,Rueca,M.,Carletti,F.,Cicalini,S.,Lapa,D.,Puro,V.,Marani,A.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Rivano Capparuccia,M.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Italy"},"clade_membership":{"value":"IIb"},"institution":{"value":"INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology"},"lineage":{"value":"B.1.5"},"strain":{"value":"INMI-Pt4"},"date":{"value":"2022-05-21"},"strain_display":{"value":"Italy/ON780017/2022-05-21"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A"]}}},{"name":"OQ339211","node_attrs":{"div":63,"accession":"OQ339211","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/ON/RKI692"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OQ339211/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","G147459A","G150551-","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG044":["K147-"]},"labels":{"aa":"OPG044: K147-"}}},{"name":"ON959173","node_attrs":{"div":64,"accession":"ON959173","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/RKI159"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/ON959173/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G78593A","C126202T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"],"OPG148":["P73S"]},"labels":{"aa":"OPG148: P73S"}}},{"name":"ON918656","node_attrs":{"div":66,"accession":"ON918656","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Taiwan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/human/Taiwan/110-231642/2022"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Taiwan/ON918656/2022-06-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C28702T","T34793C","T50861C","C51777T","G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG054":["T402A"],"OPG070":["V91A"],"OPG071":["E888K"]},"labels":{"aa":"OPG054: T402A; OPG070: V91A; OPG071: E888K"}}},{"name":"ON843165","node_attrs":{"div":62,"accession":"ON843165","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.5"},"strain":{"value":"Monkeypox/PT0033/2022"},"date":{"value":"2022-05-24"},"strain_display":{"value":"Portugal/ON843165/2022-05-24"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}}},{"name":"OP245318","node_attrs":{"div":66,"accession":"OP245318","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPX/PT0064/2022"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Portugal/OP245318/2022-08-01"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G71227A","C133867T","C134247T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G158866A"],"OPG090":["E17K"]},"labels":{"aa":"OPG090: E17K"}}},{"name":"OP450990","node_attrs":{"div":65,"accession":"OP450990","author":{"author":"Gigante,C.M.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y.","value":"Gigante,C.M.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV_USA_2022_NV0001"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP450990/2022-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G75554A","G147179A","G150590-","G150593-","G150594-","G150599-","G150602-","G159373A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG185":["E153K"]},"labels":{"aa":"OPG185: E153K"}}},{"name":"OP414288","node_attrs":{"div":62,"accession":"OP414288","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.5"},"strain":{"value":"Monkeypox/PT0244/2022"},"date":{"value":"2022-06-21"},"strain_display":{"value":"Portugal/OP414288/2022-06-21"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","-196615A"]}}},{"name":"OP536756","node_attrs":{"div":64,"accession":"OP536756","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.5"},"strain":{"value":"9000376"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP536756/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C69888T","C150392T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG089":["S8L"],"OPG176":["S195F"]},"labels":{"aa":"OPG089: S8L; OPG176: S195F"}}},{"name":"OP783902","node_attrs":{"div":62,"accession":"OP783902","author":{"author":"Laubscher,F.,Marques-Melancia,S.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Marques-Melancia,S.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Switzerland"},"clade_membership":{"value":"IIb"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"lineage":{"value":"B.1.5"},"strain":{"value":"hMPXV-CH-38347314/2022"},"date":{"value":"2022-06-08"},"strain_display":{"value":"Switzerland/OP783902/2022-06-08"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ274884","node_attrs":{"div":62,"accession":"OQ274884","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/ON/RKI665"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ274884/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OR264397","node_attrs":{"div":66,"accession":"OR264397","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.5"},"strain":{"value":"34_A"},"date":{"value":"2022-08-16"},"strain_display":{"value":"Australia/OR264397/2022-08-16"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","C30283T","C37054T","G150590-","G150593-","G150594-","G150599-","G150602-","-179197T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","G179589A","G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N"}}},{"name":"ON959175","node_attrs":{"div":62,"accession":"ON959175","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/RKI162"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/ON959175/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}}},{"name":"OP524008","node_attrs":{"div":62,"accession":"OP524008","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/RKI406"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP524008/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}}},{"name":"NODE_0000051","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["C774-","G775-","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G159001A","A196659-","T196660-"],"OPG185":["D29N"]},"labels":{"aa":"OPG185: D29N"}},"children":[{"name":"OP245340","node_attrs":{"div":63,"accession":"OP245340","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPX/PT0090/2022"},"date":{"value":"2022-07-21"},"strain_display":{"value":"Portugal/OP245340/2022-07-21"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179175T","T179244-","C179245-","G179246-","T179247-"]}}},{"name":"OP555650","node_attrs":{"div":64,"accession":"OP555650","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.5"},"strain":{"value":"Monkeypox/PT0579/2022"},"date":{"value":"2022-09-10"},"strain_display":{"value":"Portugal/OP555650/2022-09-10"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C41022T","A136552-","T136553-","C136554-"],"OPG060":["R54K"],"OPG153":["D385-"]},"labels":{"aa":"OPG060: R54K; OPG153: D385-"}}}]},{"name":"NODE_0000117","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","C160426T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A"]}},"children":[{"name":"OQ503755","node_attrs":{"div":68,"accession":"OQ503755","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.5"},"strain":{"value":"MpxV/human/USA/WA-UW-113327/2022"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"USA/OQ503755/2022-11-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T10449-","A10450-","G10451-","A10452-","T10453-","G75332A","T124690C","C135762T","C144211T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G185394A"],"OPG095":["R177K"],"OPG210":["E1347K"]},"labels":{"aa":"OPG095: R177K; OPG210: E1347K"}}},{"name":"NODE_0000118","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["G111379A","G165326A"],"OPG130":["S175L"],"OPG190":["E69K"]},"labels":{"aa":"OPG130: S175L; OPG190: E69K"}},"children":[{"name":"OP650029","node_attrs":{"div":68,"accession":"OP650029","author":{"author":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T.","value":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV22/human/USA-OK-81"},"date":{"value":"2022-07-26"},"strain_display":{"value":"USA/OP650029/2022-07-26"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G22207A","C82187T","C120671T","T136555-","G136558C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG037":["S76F"]},"labels":{"aa":"OPG037: S76F"}}},{"name":"OQ320464","node_attrs":{"div":65,"accession":"OQ320464","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV_USA_2022_NY0025"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OQ320464/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OQ721933","node_attrs":{"div":66,"accession":"OQ721933","author":{"author":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y.","value":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV_USA_2022_OH0005"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721933/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G48045A","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","G173318-","G173319-","G173320-","C173321-","A173322-","A173323-","A173324-","A173325-","C173326-","A173327-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"]}}}]}]},{"name":"NODE_0000119","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["C44333T","G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179235C"],"OPG064":["M522I"]},"labels":{"aa":"OPG064: M522I"}},"children":[{"name":"OP415189","node_attrs":{"div":63,"accession":"OP415189","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPX_luLfgA_9000208"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415189/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035702","node_attrs":{"div":67,"accession":"OR035702","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/UZ_REGA_96"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Belgium/OR035702/2022-05-30"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C29315T","C60396T","G149807A","C161572T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG046":["D139N"]},"labels":{"aa":"OPG046: D139N"}}},{"name":"OR035675","node_attrs":{"div":64,"accession":"OR035675","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/UZ_REGA_69"},"date":{"value":"2022-06-30"},"strain_display":{"value":"Belgium/OR035675/2022-06-30"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G161488A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR449646","node_attrs":{"div":64,"accession":"OR449646","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/ON/RKI932"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449646/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G149300A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","C179235-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"NODE_0000120","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["G93512T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C179235-"],"OPG113":["K594N"]},"labels":{"aa":"OPG113: K594N"}},"children":[{"name":"OP358276","node_attrs":{"div":67,"accession":"OP358276","author":{"author":"Tramuto,F.","value":"Tramuto,F."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Italy"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Palermo, Department of Health Promotion Sciences Maternal and Infant Care, Internal Medicine and Medical Specialties \"G. D'Alessandro\"\"\""},"lineage":{"value":"B.1.5"},"strain":{"value":"SIC-AOUP-UNIPA_VL_9aug"},"date":{"value":"2022-08-09"},"strain_display":{"value":"Italy/OP358276/2022-08-09"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C33103T","C114490T","C133295T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-"],"OPG049":["E17K"],"OPG133":["D403N"]},"labels":{"aa":"OPG049: E17K; OPG133: D403N"}}},{"name":"OR264417","node_attrs":{"div":65,"accession":"OR264417","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.5"},"strain":{"value":"43_A"},"date":{"value":"2022-06-22"},"strain_display":{"value":"Australia/OR264417/2022-06-22"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G2898A","C179226-","C194312T"]}}}]}]}]},{"name":"NODE_0000137","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N","clade":"B.1.2"}},"children":[{"name":"OP150927","node_attrs":{"div":62,"accession":"OP150927","author":{"author":"Gigante,C.,Pavlick,J.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y.","value":"Gigante,C.,Pavlick,J.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_USA_2022_WA001"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/OP150927/2022-05-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON929079","node_attrs":{"div":62,"accession":"ON929079","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/RKI124"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/ON929079/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP484696","node_attrs":{"div":63,"accession":"OP484696","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/RKI344"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP484696/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G118391A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OQ274892","node_attrs":{"div":62,"accession":"OQ274892","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/ON/RKI673"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ274892/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-"]}}},{"name":"OQ773441","node_attrs":{"div":62,"accession":"OQ773441","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/ON/RKI822"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773441/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"NODE_0000138","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G5375A","C191835T"],"OPG015":["A261V"],"OPG015_dup":["A261V"]},"labels":{"aa":"OPG015: A261V; OPG015_dup: A261V"}},"children":[{"name":"OP378702","node_attrs":{"div":64,"accession":"OP378702","author":{"author":"Gigante,C.M.,Johnson,S.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Riner,D.,Li,Y.","value":"Gigante,C.M.,Johnson,S.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Riner,D.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_USA_2022_MI0001"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP378702/2022-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T4775-","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C184829T","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OR759146","node_attrs":{"div":65,"accession":"OR759146","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.2"},"strain":{"value":"hMpxV/Canada/ON-PHOL053/2022"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759146/2022-08-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C3405T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C170573T","G193805A"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}}}]},{"name":"NODE_0000139","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["C20992T","G143789A","C147168T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG036":["D25N"],"OPG165":["D92N"],"OPG171":["L61F"]},"labels":{"aa":"OPG036: D25N; OPG165: D92N; OPG171: L61F"}},"children":[{"name":"OP279039","node_attrs":{"div":65,"accession":"OP279039","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/CAN/UN-NML-4117/2022"},"date":{"value":"2022-06-28"},"strain_display":{"value":"Canada/OP279039/2022-06-28"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OP355567","node_attrs":{"div":66,"accession":"OP355567","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/ON/RKI307"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP355567/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G49821A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A188351-"],"OPG068":["E541K"]},"labels":{"aa":"OPG068: E541K"}}},{"name":"OR264414","node_attrs":{"div":65,"accession":"OR264414","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.2"},"strain":{"value":"42_C"},"date":{"value":"2022-06-22"},"strain_display":{"value":"Australia/OR264414/2022-06-22"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T"]}}}]},{"name":"NODE_0000140","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188391T"]}},"children":[{"name":"OP205083","node_attrs":{"div":63,"accession":"OP205083","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_UK_2022_9000092"},"date":{"value":"2022-05-25"},"strain_display":{"value":"United Kingdom/OP205083/2022-05-25"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP205086","node_attrs":{"div":63,"accession":"OP205086","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_UK_2022_9000097"},"date":{"value":"2022-06-06"},"strain_display":{"value":"United Kingdom/OP205086/2022-06-06"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP415205","node_attrs":{"div":72,"accession":"OP415205","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPX_TcUINH_9000230"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415205/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T11371C","G34303A","C85322T","G92048A","G123119A","G129583A","C140931T","C153104T","C178378T"],"OPG053":["P130S"],"OPG143":["S66L"],"OPG180":["S138F"]},"labels":{"aa":"OPG053: P130S; OPG143: S66L; OPG180: S138F"}}},{"name":"OP536784","node_attrs":{"div":63,"accession":"OP536784","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.2"},"strain":{"value":"9000408"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536784/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OP605583","node_attrs":{"div":68,"accession":"OP605583","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"lineage":{"value":"B.1.2"},"strain":{"value":"Slovenia-MPXV-42-2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Slovenia/OP605583/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A161-","-607T","C17614A","C27187T","G111484A","G147305A","C159401A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG030":["V74L"],"OPG043":["D257N"],"OPG130":["T140I"],"OPG185":["S162Y"]},"labels":{"aa":"OPG030: V74L; OPG043: D257N; OPG130: T140I; OPG185: S162Y"}}},{"name":"OP555625","node_attrs":{"div":65,"accession":"OP555625","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.2"},"strain":{"value":"Monkeypox/PT0554/2022"},"date":{"value":"2022-08-30"},"strain_display":{"value":"Portugal/OP555625/2022-08-30"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G29102A","G45781A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG045":["S54L"],"OPG064":["H40Y"]},"labels":{"aa":"OPG045: S54L; OPG064: H40Y"}}},{"name":"OP881946","node_attrs":{"div":67,"accession":"OP881946","author":{"author":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y.","value":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_USA_2022_FL0027"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OP881946/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G65961A","G126646A","C168226T","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C188998T"],"OPG084":["E414K"],"OPG148":["E221K"]},"labels":{"aa":"OPG084: E414K; OPG148: E221K"}}},{"name":"OQ626772","node_attrs":{"div":66,"accession":"OQ626772","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV22/human/USA-NE-341"},"date":{"value":"2022-10-11"},"strain_display":{"value":"USA/OQ626772/2022-10-11"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G10523A","A16620-","T16621-","C16622-","G92433A","C160426T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A","-196616A","-196617A"],"OPG029":["D154-"],"OPG113":["A235T"]},"labels":{"aa":"OPG029: D154-; OPG113: A235T"}}},{"name":"OR086973","node_attrs":{"div":64,"accession":"OR086973","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/UZ_REGA_164/Belgium/2022"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR086973/2022-07-27"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G135633A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"NODE_0000141","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G133968T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}},"children":[{"name":"OP881952","node_attrs":{"div":66,"accession":"OP881952","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_USA_2022_TX0030"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP881952/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G164971A","C188929T"],"OPG189":["E547K"]},"labels":{"aa":"OPG189: E547K"}}},{"name":"OQ503827","node_attrs":{"div":70,"accession":"OQ503827","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00404/2023"},"date":{"value":"2023-01-10"},"strain_display":{"value":"USA/OQ503827/2023-01-10"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G25309A","G28271A","G112785A","T118096C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C165231T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C180371T"],"OPG040":["S57L"],"OPG044":["D61N"],"OPG136":["M498V"],"OPG190":["S37L"]},"labels":{"aa":"OPG040: S57L; OPG044: D61N; OPG136: M498V; OPG190: S37L"}}}]},{"name":"NODE_0000142","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["T26669C","G96073A","G115235A","C125294T"],"OPG117":["D9N"]},"labels":{"aa":"OPG117: D9N"}},"children":[{"name":"OQ159027","node_attrs":{"div":69,"accession":"OQ159027","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/RKI632"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"Germany/OQ159027/2022-11-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G77052A","C135868T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP959060","node_attrs":{"div":67,"accession":"OP959060","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"lineage":{"value":"B.1.2"},"strain":{"value":"BOL-UNIMOL-MPX-293428-L"},"date":{"value":"2022-10-29"},"strain_display":{"value":"Colombia/OP959060/2022-10-29"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000143","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["C27730T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A","-196616A","-196617A"],"OPG043":["D76N"]},"labels":{"aa":"OPG043: D76N"}},"children":[{"name":"OP890528","node_attrs":{"div":65,"accession":"OP890528","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00295/2022"},"date":{"value":"2022-11-01"},"strain_display":{"value":"USA/OP890528/2022-11-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G176439A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG205":["D262N"]},"labels":{"aa":"OPG205: D262N"}}},{"name":"OQ603479","node_attrs":{"div":66,"accession":"OQ603479","author":{"author":"Haw,M.,Kath,C.,Espinosa,A.,O'Neil,R.,Hacker,J.","value":"Haw,M.,Kath,C.,Espinosa,A.,O'Neil,R.,Hacker,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDPH, VRDL"},"lineage":{"value":"B.1.2"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000210/2023"},"date":{"value":"2022-07-09"},"strain_display":{"value":"USA/OQ603479/2022-07-09"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G130555A","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","G149400A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG151":["M544I"]},"labels":{"aa":"OPG151: M544I"}}}]},{"name":"NODE_0000144","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T157527C","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}},"children":[{"name":"OP415265","node_attrs":{"div":68,"accession":"OP415265","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPX_7eECz2_9000326"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415265/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C46023T","C114099T","G149805A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G166317A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG133":["R533Q"],"OPG175":["E122K"],"OPG191":["D53N"]},"labels":{"aa":"OPG133: R533Q; OPG175: E122K; OPG191: D53N"}}},{"name":"OP555483","node_attrs":{"div":65,"accession":"OP555483","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.2"},"strain":{"value":"Monkeypox/PT0387/2022"},"date":{"value":"2022-07-12"},"strain_display":{"value":"Portugal/OP555483/2022-07-12"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G154098A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"]}}},{"name":"OR449642","node_attrs":{"div":64,"accession":"OR449642","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/ON/RKI928"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449642/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}}]},{"name":"NODE_0000145","node_attrs":{"div":69,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G8638A","C21548T","C47820T","C68218T","C188236T","C188339T"],"OPG037":["D296N"],"OPG085":["R105Q"]},"labels":{"aa":"OPG037: D296N; OPG085: R105Q"}},"children":[{"name":"OR427347","node_attrs":{"div":71,"accession":"OR427347","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/USA/WA-UW-025109/2023"},"date":{"value":"2023-02-XX"},"strain_display":{"value":"USA/OR427347/2023-02-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","G12239A","G12488A","-196615A"],"OPG023":["S138L","S221F"]},"labels":{"aa":"OPG023: S138L, S221F"}}},{"name":"OR427346","node_attrs":{"div":69,"accession":"OR427346","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/USA/WA-UW-048416/2023"},"date":{"value":"2023-04-XX"},"strain_display":{"value":"USA/OR427346/2023-04-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-"]}}},{"name":"OR427341","node_attrs":{"div":71,"accession":"OR427341","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/USA/WA-UW-039072/2023"},"date":{"value":"2023-03-XX"},"strain_display":{"value":"USA/OR427341/2023-03-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G156482A","C175867T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG205":["S71F"]},"labels":{"aa":"OPG205: S71F"}}},{"name":"OR464212","node_attrs":{"div":70,"accession":"OR464212","author":{"author":"Gigante,C.,Goldoft,M.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Holshue,M.,Li,Y.","value":"Gigante,C.,Goldoft,M.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Holshue,M.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_USA_2022_WA0018"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR464212/2022-12-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","T126424A","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"],"OPG148":["S147T"]},"labels":{"aa":"OPG148: S147T"}}}]}]}]},{"name":"NODE_0000146","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C25644T","-179172C","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C"]},"labels":{"clade":"B.1.7"}},"children":[{"name":"ON843170","node_attrs":{"div":62,"accession":"ON843170","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.7"},"strain":{"value":"Monkeypox/PT0031/2022"},"date":{"value":"2022-05-26"},"strain_display":{"value":"Portugal/ON843170/2022-05-26"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"]}}},{"name":"OP205081","node_attrs":{"div":62,"accession":"OP205081","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_UK_2022_9000078"},"date":{"value":"2022-06-14"},"strain_display":{"value":"United Kingdom/OP205081/2022-06-14"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179173A","-179174T","-179175T","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP415238","node_attrs":{"div":63,"accession":"OP415238","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPX_GGr0lD_9000276"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415238/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","C39935T","-179173A","-179174T","-179175T","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OQ547747","node_attrs":{"div":62,"accession":"OQ547747","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/ON/RKI720"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ547747/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150551-","G150568-","A150569-","T150570-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OQ702773","node_attrs":{"div":64,"accession":"OQ702773","author":{"author":"Gigante,C.,Berns,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Carpenter-Azevedo,K.,Li,Y.","value":"Gigante,C.,Berns,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Carpenter-Azevedo,K.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_USA_2022_RI0005"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OQ702773/2022-07-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G98456A","C103258T","-179173A","-179174T","-179175T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A"],"OPG118":["G4E"],"OPG123":["D605N"]},"labels":{"aa":"OPG118: G4E; OPG123: D605N"}}},{"name":"OR264460","node_attrs":{"div":64,"accession":"OR264460","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.7"},"strain":{"value":"7_B"},"date":{"value":"2022-07-11"},"strain_display":{"value":"Australia/OR264460/2022-07-11"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G144556A","C170573T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}}},{"name":"OR264376","node_attrs":{"div":64,"accession":"OR264376","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.7"},"strain":{"value":"23_A"},"date":{"value":"2022-08-18"},"strain_display":{"value":"Australia/OR264376/2022-08-18"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","G46562A","T76084-","T76085-","C98821T","-179173A","-179174T","-179175T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG044":["K147-"],"OPG118":["R126C"]},"labels":{"aa":"OPG044: K147-; OPG118: R126C"}}},{"name":"NODE_0000147","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G63147A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}},"children":[{"name":"ON918611","node_attrs":{"div":67,"accession":"ON918611","author":{"author":"Chan,W.Y.,Mtshali,S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J.","value":"Chan,W.Y.,Mtshali,S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"South Africa"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute for Communicable Disease, Sequencing Core Facility"},"lineage":{"value":"B.1.7"},"strain":{"value":"NICD-SVPL223"},"date":{"value":"2022-06-20"},"strain_display":{"value":"South Africa/ON918611/2022-06-20"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","G10224A","G129761A","T143625A","C177847T","C179172-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","-196615A"],"OPG021":["R213Q"],"OPG151":["D280N"],"OPG165":["I37N"],"OPG205":["S731L"]},"labels":{"aa":"OPG021: R213Q; OPG151: D280N; OPG165: I37N; OPG205: S731L"}}},{"name":"OP536776","node_attrs":{"div":65,"accession":"OP536776","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.7"},"strain":{"value":"9000398"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536776/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C157854T","C164272T","-179173A","-179174T","-179175T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A190779-","C190780-","T190781-","G190782-","A190783-","A190784-","A190785-","T190786-","T190787-"],"OPG016":["T124-","E125-","I126-"],"OPG189":["R314C"]},"labels":{"aa":"OPG016: T124-, E125-, I126-; OPG189: R314C"}}}]},{"name":"NODE_0000148","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C14077T","-179173A","-179174T","-179175T","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP205084","node_attrs":{"div":65,"accession":"OP205084","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_UK_2022_9000093"},"date":{"value":"2022-05-30"},"strain_display":{"value":"United Kingdom/OP205084/2022-05-30"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C4529T","G155585A","G192681A"],"OPG003":["D27N"],"OPG003_dup":["D27N"]},"labels":{"aa":"OPG003: D27N; OPG003_dup: D27N"}}},{"name":"OP415197","node_attrs":{"div":66,"accession":"OP415197","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPX_2v76E1_9000221"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415197/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G41557A","G91376A","G105860A"],"OPG061":["P110S"],"OPG112":["D44N"]},"labels":{"aa":"OPG061: P110S; OPG112: D44N"}}}]},{"name":"NODE_0000149","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G120241A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"],"OPG137":["D214N"]},"labels":{"aa":"OPG137: D214N"}},"children":[{"name":"ON911481","node_attrs":{"div":66,"accession":"ON911481","author":{"author":"Galan-Huerta,K.A.,Paz-Infanzon,M.,Ruiz-Higareda,A.F.,Nuzzolo-Shihadeh,L.,Camacho-Ortiz,A.,Bocanegra-Ibarias,P.,Rivas-Estilla,A.M.,Zacarias-Villarreal,D.,Yamallel-Ortega,L.A.,Guerrero-Putz,M.D.,Ocampo-Candiani,J.","value":"Galan-Huerta,K.A.,Paz-Infanzon,M.,Ruiz-Higareda,A.F.,Nuzzolo-Shihadeh,L.,Camacho-Ortiz,A.,Bocanegra-Ibarias,P.,Rivas-Estilla,A.M.,Zacarias-Villarreal,D.,Yamallel-Ortega,L.A.,Guerrero-Putz,M.D.,Ocampo-Candiani,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Mexico"},"clade_membership":{"value":"IIb"},"institution":{"value":"Universidad Autonoma de Nuevo Leon - Facultad de Medicina, Centro de Investigacion e Innovacion en Virologia Medica"},"lineage":{"value":"B.1.7"},"strain":{"value":"Monkeypox/MX-UANL001/2022"},"date":{"value":"2022-06-28"},"strain_display":{"value":"Mexico/ON911481/2022-06-28"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","G57088A","C127530T","T133098-","T133099-","T133100-","T133101-","T133102-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","T168120C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG074":["S13L"],"OPG149":["S112L"],"OPG193":["F263L"]},"labels":{"aa":"OPG074: S13L; OPG149: S112L; OPG193: F263L"}}},{"name":"OP935994","node_attrs":{"div":63,"accession":"OP935994","author":{"author":"Bajwa,M.I.,Miller,H.","value":"Bajwa,M.I.,Miller,H."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Delaware Public Health Lab, Sequencing/Bioinformatics"},"lineage":{"value":"B.1.7"},"strain":{"value":"B1118431"},"date":{"value":"2022-09-27"},"strain_display":{"value":"USA/OP935994/2022-09-27"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"NODE_0000150","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C168226T","C175467T"]}},"children":[{"name":"OP484682","node_attrs":{"div":65,"accession":"OP484682","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/RKI361"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP484682/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OQ547765","node_attrs":{"div":65,"accession":"OQ547765","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/ON/RKI738"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OQ547765/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150563-","T150564-","G150565-","A150566-","T150567-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}}]}]},{"name":"NODE_0000151","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C148771T"],"OPG174":["D209N"]},"labels":{"aa":"OPG174: D209N"}},"children":[{"name":"OR449630","node_attrs":{"div":65,"accession":"OR449630","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/ON/RKI916"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449630/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G69840A","C99542T","G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG118":["S366F"],"OPG193":["F263-"]},"labels":{"aa":"OPG118: S366F; OPG193: F263-"}}},{"name":"NODE_0000152","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G114316A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG133":["H461Y"]},"labels":{"aa":"OPG133: H461Y"}},"children":[{"name":"OR087006","node_attrs":{"div":68,"accession":"OR087006","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/UZ_REGA_197/Belgium/2022"},"date":{"value":"2022-08-03"},"strain_display":{"value":"Belgium/OR087006/2022-08-03"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C12637T","G53377A","T133102-","C178569T","-179173A","-179174T","-179175T","-179191A","-179192T","-179193T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C182707T"],"OPG210":["S451F"]},"labels":{"aa":"OPG210: S451F"}}},{"name":"NODE_0000153","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G152437A"]}},"children":[{"name":"OQ159026","node_attrs":{"div":66,"accession":"OQ159026","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/RKI631"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"Germany/OQ159026/2022-10-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150547A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","G187677A"]}}},{"name":"OQ627928","node_attrs":{"div":65,"accession":"OQ627928","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Italy"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"lineage":{"value":"B.1.7"},"strain":{"value":"INMI-19442022"},"date":{"value":"2022-09-14"},"strain_display":{"value":"Italy/OQ627928/2022-09-14"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-608T","G610-","T611-","A612-"]}}}]}]}]},{"name":"NODE_0000154","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G42504A","-179173A","-179174T","-179175T"]}},"children":[{"name":"OP205076","node_attrs":{"div":63,"accession":"OP205076","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_UK_2022_9000070"},"date":{"value":"2022-06-09"},"strain_display":{"value":"United Kingdom/OP205076/2022-06-09"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP204840","node_attrs":{"div":64,"accession":"OP204840","author":{"author":"Seang,S.,Burrel,S.,Todesco,E.,Leducq,V.,Monsel,G.,Le Pluart,D.,Cordevant,C.,Pourcher,V.,Palich,R.,Charpentier,C.","value":"Seang,S.,Burrel,S.,Todesco,E.,Leducq,V.,Monsel,G.,Le Pluart,D.,Cordevant,C.,Pourcher,V.,Palich,R.,Charpentier,C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"APHP Pitie Salpetriere SU, Virology"},"lineage":{"value":"B.1.7"},"strain":{"value":"PatientMPXV"},"date":{"value":"2022-06-10"},"strain_display":{"value":"France/OP204840/2022-06-10"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G163250A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196612-","A196613-","A196614-"]}}},{"name":"OR463715","node_attrs":{"div":64,"accession":"OR463715","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/ON/RKI768"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OR463715/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C159741T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","A181253-"]}}},{"name":"NODE_0000155","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C115870T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"]}},"children":[{"name":"OP414322","node_attrs":{"div":64,"accession":"OP414322","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.7"},"strain":{"value":"Monkeypox/PT0287/2022"},"date":{"value":"2022-06-10"},"strain_display":{"value":"Portugal/OP414322/2022-06-10"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-196615A"]}}},{"name":"NODE_0000156","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C5292T","G11924A","G74267A","A161784T","G191918A"],"OPG015":["D289N"],"OPG015_dup":["D289N"],"OPG023":["S326L"],"OPG094":["R163Q"]},"labels":{"aa":"OPG015: D289N; OPG015_dup: D289N; OPG023: S326L; OPG094: R163Q"}},"children":[{"name":"OP245331","node_attrs":{"div":68,"accession":"OP245331","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPX/PT0077/2022"},"date":{"value":"2022-07-28"},"strain_display":{"value":"Portugal/OP245331/2022-07-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP555568","node_attrs":{"div":70,"accession":"OP555568","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.7"},"strain":{"value":"Monkeypox/PT0493/2022"},"date":{"value":"2022-08-11"},"strain_display":{"value":"Portugal/OP555568/2022-08-11"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G125379A","G176342A"],"OPG145":["R478K"]},"labels":{"aa":"OPG145: R478K"}}}]}]}]},{"name":"NODE_0000157","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C57173T","C179172-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"]}},"children":[{"name":"OP727822","node_attrs":{"div":70,"accession":"OP727822","author":{"author":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K.","value":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"lineage":{"value":"B.1.7"},"strain":{"value":"PrEV_case_2"},"date":{"value":"2022-10-02"},"strain_display":{"value":"Belgium/OP727822/2022-10-02"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T604-","T605-","T606-","C11401T","C33964T","C36267T","G110285A","T133102-","C144366T","A174924T","G180608A","A188351-","G195316A"],"OPG052":["R11Q"],"OPG055":["D273N"],"OPG209":["E31K"]},"labels":{"aa":"OPG052: R11Q; OPG055: D273N; OPG209: E31K"}}},{"name":"NODE_0000158","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C142797T"],"OPG164":["S7L"]},"labels":{"aa":"OPG164: S7L"}},"children":[{"name":"OP279036","node_attrs":{"div":64,"accession":"OP279036","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.7"},"strain":{"value":"MpxV/human/CAN/UN-NML-4112/2022"},"date":{"value":"2022-06-30"},"strain_display":{"value":"Canada/OP279036/2022-06-30"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP378695","node_attrs":{"div":64,"accession":"OP378695","author":{"author":"Gigante,C.M.,Hauser,J.R.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y.","value":"Gigante,C.M.,Hauser,J.R.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_USA_2022_DC0010"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP378695/2022-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T4775-","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP480419","node_attrs":{"div":69,"accession":"OP480419","author":{"author":"Deanhardt,B.,Miller,M.,Wang,J.R.","value":"Deanhardt,B.,Miller,M.,Wang,J.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of North Carolina at Chapel Hill, Department of Genetics"},"lineage":{"value":"B.1.7"},"strain":{"value":"hMPXV/USA/NC-UNC-0020/2022"},"date":{"value":"2022-08-30"},"strain_display":{"value":"USA/OP480419/2022-08-30"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C23868T","A31053G","C128717T","G143512A","C173533A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG039":["G84E"],"OPG047":["C48R"]},"labels":{"aa":"OPG039: G84E; OPG047: C48R"}}},{"name":"OP920699","node_attrs":{"div":70,"accession":"OP920699","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00361/2022"},"date":{"value":"2022-10-31"},"strain_display":{"value":"USA/OP920699/2022-10-31"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G105325A","C108658T","G111379A","C149889T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G165395A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G184244A"],"OPG124":["S215F"],"OPG130":["S175L"],"OPG190":["E92K"]},"labels":{"aa":"OPG124: S215F; OPG130: S175L; OPG190: E92K"}}},{"name":"OR264396","node_attrs":{"div":69,"accession":"OR264396","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.7"},"strain":{"value":"33_A"},"date":{"value":"2022-09-07"},"strain_display":{"value":"Australia/OR264396/2022-09-07"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G14622A","A28529-","A28530-","T76084-","T76085-","G101241A","T133102-","C136244T","C156446T","G174708A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG025":["R216C"],"OPG044":["K147-"],"OPG153":["R475K"],"OPG204":["M59I"]},"labels":{"aa":"OPG025: R216C; OPG044: K147-; OPG153: R475K; OPG204: M59I"}}},{"name":"OR209323","node_attrs":{"div":65,"accession":"OR209323","author":{"author":"Li,C.M.","value":"Li,C.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_USA_2022_NC0003"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR209323/2022-12-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","G62268A","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","A196614-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OR759196","node_attrs":{"div":64,"accession":"OR759196","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.7"},"strain":{"value":"hMpxV/Canada/ON-PHOL108/2022"},"date":{"value":"2022-07-01"},"strain_display":{"value":"Canada/OR759196/2022-07-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR759178","node_attrs":{"div":68,"accession":"OR759178","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.7"},"strain":{"value":"hMpxV/Canada/ON-PHOL090/2022"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759178/2022-09-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","G26352A","C30137T","C55072T","G130068A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"],"OPG042":["A249V"],"OPG047":["R353K"],"OPG073":["D24N"],"OPG151":["R382Q"]},"labels":{"aa":"OPG042: A249V; OPG047: R353K; OPG073: D24N; OPG151: R382Q"}}},{"name":"OR759164","node_attrs":{"div":64,"accession":"OR759164","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.7"},"strain":{"value":"hMpxV/Canada/ON-PHOL075/2022"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759164/2022-08-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000159","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C55036T","C96914T","G158254A","C170381T","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179176A","-179177T","-179178A","-179179T","-179180A"],"OPG073":["E36K"],"OPG117":["S289L"],"OPG198":["S115L"]},"labels":{"aa":"OPG073: E36K; OPG117: S289L; OPG198: S115L"}},"children":[{"name":"OQ918697","node_attrs":{"div":72,"accession":"OQ918697","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00486/2023"},"date":{"value":"2023-02-18"},"strain_display":{"value":"USA/OQ918697/2023-02-18"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G73789A","C136435T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C166803T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","G178559A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG094":["G4R"],"OPG192":["P25S"]},"labels":{"aa":"OPG094: G4R; OPG192: P25S"}}},{"name":"OR464216","node_attrs":{"div":68,"accession":"OR464216","author":{"author":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y.","value":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_USA_2022_KS0007"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"USA/OR464216/2022-11-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T"]}}}]}]}]}]},{"name":"NODE_0000160","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["G74360A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179235C"],"OPG094":["R194H"]},"labels":{"aa":"OPG094: R194H","clade":"B.1.1"}},"children":[{"name":"OP055805","node_attrs":{"div":62,"accession":"OP055805","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.1"},"strain":{"value":"MpxV/human/USA/Unknown-UW-076991/2022"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OP055805/2022-07-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C133103T","-179198A","-179199C","-179200A","-179201T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON792321","node_attrs":{"div":62,"accession":"ON792321","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Switzerland"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba6450e/2022"},"date":{"value":"2022-06-02"},"strain_display":{"value":"Switzerland/ON792321/2022-06-02"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","A19360-","T19361-","C19362-","A19363-","T19364-","T19365-","A43653-","T43654-","T43655-","A49176-","A49177-","T49178-","T49179-","T49180-","T49181-","A49182-","T49183-","T49184-","A49185-","A49186-","C49187-","G49188-","G49189-","T49190-","A49191-","A49192-","T49193-","A79063-","A79064-","T79065-","T79066-","T79067-","T79068-","A79069-","A79070-","T79071-","A79072-","T79073-","A79074-","A79075-","T79076-","A79077-","C79078-","T79079-","T79080-","A79081-","A79082-","A79083-","A79084-","A79085-","T79086-","G79087-","G79088-","A79089-","T79090-","G79091-","T79092-","T79093-","G79094-","T79095-","G79096-","T79097-","C79098-","G79099-","T79100-","T79101-","A79102-","A152691-","A152692-","T152693-","G152694-","A152695-","C152696-","G152697-","T152698-","A175944-","T175945-","A175946-","T175947-","C175948-","A175949-","A175950-","C179127A","C179136T","T179138A","T179148-","T179157-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","C179190T","-179198A","-179199C","-179200A","-179201T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T180493-","A180494-","T180495-","C180496-","A180497-","T180498-","T180499-"],"OPG063":["D50-"],"OPG068":["N329-","G330-","N331-","T332-","F333-","I334-"],"OPG205":["I97-","S98-","I99-"]},"labels":{"aa":"OPG063: D50-; OPG068: N329-, G330-, N331-, T332-, F333-, I334-; OPG205: I97-, S98-, I99-"}}},{"name":"ON694337","node_attrs":{"div":63,"accession":"ON694337","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/RKI020"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/ON694337/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C152033T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179235-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP303785","node_attrs":{"div":62,"accession":"OP303785","author":{"author":"Gigante,C.M.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.M.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV_USA_2022_IL0042"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP303785/2022-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179235-"]}}},{"name":"OP204857","node_attrs":{"div":64,"accession":"OP204857","author":{"author":"Rhie,G.-E.","value":"Rhie,G.-E."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"South Korea"},"clade_membership":{"value":"IIb"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV-ROK-P1-2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"South Korea/OP204857/2022-08-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C786T","C71728T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G173429A","-179198A","-179199C","-179200A","-179201T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG091":["A120V"]},"labels":{"aa":"OPG091: A120V"}}},{"name":"OP382488","node_attrs":{"div":63,"accession":"OP382488","author":{"author":"Colson,P.","value":"Colson,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMPXV-IHU00011"},"date":{"value":"2022-07-19"},"strain_display":{"value":"France/OP382488/2022-07-19"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C153387T","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP536800","node_attrs":{"div":62,"accession":"OP536800","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.1"},"strain":{"value":"9000426"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP536800/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179198A","-179199C","-179200A","-179201T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T190786-","T190787-","A196614-"]}}},{"name":"OP837475","node_attrs":{"div":64,"accession":"OP837475","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.1"},"strain":{"value":"DC_INS_MPX_1009_L"},"date":{"value":"2022-09-19"},"strain_display":{"value":"Colombia/OP837475/2022-09-19"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C17764T","G54336A","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG030":["D24N"],"OPG071":["P35S"]},"labels":{"aa":"OPG030: D24N; OPG071: P35S"}}},{"name":"OP894029","node_attrs":{"div":67,"accession":"OP894029","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI609"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP894029/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C3850T","C93296T","G117944A","G143995A","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","T150567-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155986A","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179235-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"],"OPG003":["R253Q"]},"labels":{"aa":"OPG003: R253Q"}}},{"name":"OQ427112","node_attrs":{"div":65,"accession":"OQ427112","author":{"author":"Gigante,C.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y.","value":"Gigante,C.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV_USA_2022_NV0005"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ427112/2022-10-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C11401T","C72269T","T133102-","A136552-","T136553-","C136554-","G140194A","G158318A","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179235-"],"OPG092":["D227N"],"OPG153":["D385-"],"OPG159":["D143N"],"OPG160":["S294L"]},"labels":{"aa":"OPG092: D227N; OPG153: D385-; OPG159: D143N; OPG160: S294L"}}},{"name":"OR264399","node_attrs":{"div":64,"accession":"OR264399","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.1"},"strain":{"value":"36_A"},"date":{"value":"2022-06-30"},"strain_display":{"value":"Australia/OR264399/2022-06-30"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","A43500-","T76084-","T76085-","T80846-","T80847-","A89106-","G118500A","T121121-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","G160406A","-179198A","-179199C","-179200A","-179201T","C179235-","C196772-","A196773-","T196774-"],"OPG044":["K147-"],"OPG136":["T363M"]},"labels":{"aa":"OPG044: K147-; OPG136: T363M"}}},{"name":"OR264368","node_attrs":{"div":63,"accession":"OR264368","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.1"},"strain":{"value":"15_B"},"date":{"value":"2022-08-22"},"strain_display":{"value":"Australia/OR264368/2022-08-22"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","T76084-","T76085-","T80846-","T80847-","T121121-","T133094-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-179198A","-179199C","-179200A","-179201T","C179235-","G183484A"],"OPG044":["K147-"],"OPG210":["R710K"]},"labels":{"aa":"OPG044: K147-; OPG210: R710K"}}},{"name":"OR095036","node_attrs":{"div":65,"accession":"OR095036","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/UZ_REGA_218/Belgium/2022"},"date":{"value":"2022-08-08"},"strain_display":{"value":"Belgium/OR095036/2022-08-08"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C25828T","G107496A","G109463A","-179198A","-179199C","-179200A","-179201T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG042":["E424K"]},"labels":{"aa":"OPG042: E424K"}}},{"name":"OR500080","node_attrs":{"div":71,"accession":"OR500080","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Romania"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Romania/B-18/2022"},"date":{"value":"2022-08-16"},"strain_display":{"value":"Romania/OR500080/2022-08-16"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G17189T","A55140C","T55141A","T75369C","T91506G","G121663A","T169776C","A173282G","A173284G","T174471A","G179029T","A179046T","A179081T","A179110T","T179121A","C179127T","T179129-","T179130-","T179139A","C179172A","C179190T","-179198A","-179200A","-179201T","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C179672A","C181209T"],"OPG073":["M1W"],"OPG074":["N662M"],"OPG208":["S136Y"]},"labels":{"aa":"OPG073: M1W; OPG074: N662M; OPG208: S136Y"}}},{"name":"OR500078","node_attrs":{"div":62,"accession":"OR500078","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Romania"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Romania/B-8/2022"},"date":{"value":"2022-06-29"},"strain_display":{"value":"Romania/OR500078/2022-06-29"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T92388-","-179198A","-179199C","-179200A","-179201T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["F220-"]},"labels":{"aa":"OPG113: F220-"}}},{"name":"ON694329","node_attrs":{"div":62,"accession":"ON694329","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/RKI025"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/ON694329/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179235-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-","A192490-","A192491-","G192492-","T192493-","T192494-","A192495-","G192496-","T192497-","T192498-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP310042","node_attrs":{"div":62,"accession":"OP310042","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.1"},"strain":{"value":"MpxV/human/USA/WA-UW-089266/2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP310042/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-179198A","-179199C","-179200A","-179201T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A"]}}},{"name":"NODE_0000162","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C17048T","G93828A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177009A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179235-"],"OPG029":["D8N"],"OPG113":["E700K"],"OPG205":["E452K"]},"labels":{"aa":"OPG029: D8N; OPG113: E700K; OPG205: E452K"}},"children":[{"name":"OQ159028","node_attrs":{"div":66,"accession":"OQ159028","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/RKI633"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"Germany/OQ159028/2022-11-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C41131T"],"OPG060":["E18K"]},"labels":{"aa":"OPG060: E18K"}}},{"name":"OQ735077","node_attrs":{"div":72,"accession":"OQ735077","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/PT0626/2023"},"date":{"value":"2023-03-21"},"strain_display":{"value":"Portugal/OQ735077/2023-03-21"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-609T","A615-","C616-","C10929T","C22179T","G39515A","G77076A","G129659A","C129949T","G139167A","C196638-","T196639-"],"OPG023":["E658K"],"OPG151":["E246K"]},"labels":{"aa":"OPG023: E658K; OPG151: E246K"}}}]},{"name":"NODE_0000163","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["G52232A","C119838T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG071":["S736L"]},"labels":{"aa":"OPG071: S736L"}},"children":[{"name":"OQ320518","node_attrs":{"div":65,"accession":"OQ320518","author":{"author":"Gigante,C.,Culbertson,M.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Pope,B.,Li,Y.","value":"Gigante,C.,Culbertson,M.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Pope,B.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV_USA_2022_IN0006"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ320518/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T22135C","A136552-","T136553-","C136554-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","-179198A","-179199C","-179200A","-179201T"],"OPG037":["H100R"],"OPG153":["D385-"]},"labels":{"aa":"OPG037: H100R; OPG153: D385-"}}},{"name":"OR427334","node_attrs":{"div":70,"accession":"OR427334","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.1"},"strain":{"value":"MpxV/human/USA/WA-UW-121247/2022"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR427334/2022-12-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","C11810T","G59218A","C63120T","G75522A","C159899T","G160110A","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","-196615A"],"OPG023":["R364K"],"OPG079":["S135L"]},"labels":{"aa":"OPG023: R364K; OPG079: S135L"}}}]},{"name":"NODE_0000164","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C46672T","C56805T","C72314T","C103216T","C127628T","T152686-","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C180857T"],"OPG066":["E253K"],"OPG074":["M107I"],"OPG092":["D212N"],"OPG123":["V619I"],"OPG149":["P145S"]},"labels":{"aa":"OPG066: E253K; OPG074: M107I; OPG092: D212N; OPG123: V619I; OPG149: P145S"}},"children":[{"name":"OR500086","node_attrs":{"div":71,"accession":"OR500086","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Romania"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Romania/B-35_R3/2023"},"date":{"value":"2023-02-15"},"strain_display":{"value":"Romania/OR500086/2023-02-15"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C42674T","G169748A","C179190T","T179192A","T179193A","-179198G","A185438C","C185439A"],"OPG063":["E339K"]},"labels":{"aa":"OPG063: E339K"}}},{"name":"OR500081","node_attrs":{"div":69,"accession":"OR500081","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Romania"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Romania/B-35_L1/2023"},"date":{"value":"2023-01-05"},"strain_display":{"value":"Romania/OR500081/2023-01-05"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C16327T","-179198A","-179199C","-179200A","-179201T"]}}}]},{"name":"NODE_0000165","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["G155698A"]}},"children":[{"name":"OR759194","node_attrs":{"div":72,"accession":"OR759194","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Canada/ON-PHOL106/2022"},"date":{"value":"2022-07-01"},"strain_display":{"value":"Canada/OR759194/2022-07-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C7235T","C32798T","C55589T","C61706T","G115768A","T120124-","T120125-","A120126-","G120127-","A120128-","T120129-","A120130-","A120131-","T120132-","G127806A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159118A","G162726A","C177833T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179235-"],"OPG074":["E513K"],"OPG080":["V105I"],"OPG134":["D7N"],"OPG137":["L175-","D176-","N177-"],"OPG150":["E10K"],"OPG185":["D68N"]},"labels":{"aa":"OPG074: E513K; OPG080: V105I; OPG134: D7N; OPG137: L175-, D176-, N177-; OPG150: E10K; OPG185: D68N"}}},{"name":"NODE_0000166","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["G161575A","-179198A","-179199C","-179200A","-179201T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OR459775","node_attrs":{"div":66,"accession":"OR459775","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"South Korea"},"clade_membership":{"value":"IIb"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV-ROK-P002-2022"},"date":{"value":"2022-09-02"},"strain_display":{"value":"South Korea/OR459775/2022-09-02"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G14640A","C108843T","G136558C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG025":["H210Y"],"OPG153":["I370M"]},"labels":{"aa":"OPG025: H210Y; OPG153: I370M"}}},{"name":"OR086958","node_attrs":{"div":64,"accession":"OR086958","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/UZ_REGA_149/Belgium/2022"},"date":{"value":"2022-07-05"},"strain_display":{"value":"Belgium/OR086958/2022-07-05"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133102-"]}}}]}]},{"name":"NODE_0000167","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C29887T","-179198A","-179199C","-179200A","-179201T","C179235-"]}},"children":[{"name":"OR264437","node_attrs":{"div":63,"accession":"OR264437","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.1"},"strain":{"value":"56_C"},"date":{"value":"2022-09-06"},"strain_display":{"value":"Australia/OR264437/2022-09-06"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-"],"OPG044":["K147-"]},"labels":{"aa":"OPG044: K147-"}}},{"name":"OR264424","node_attrs":{"div":63,"accession":"OR264424","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.1"},"strain":{"value":"47_A"},"date":{"value":"2022-07-13"},"strain_display":{"value":"Australia/OR264424/2022-07-13"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OR264455","node_attrs":{"div":63,"accession":"OR264455","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.1"},"strain":{"value":"67_D"},"date":{"value":"2022-08-25"},"strain_display":{"value":"Australia/OR264455/2022-08-25"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T76084-","T76085-","T80846-","T80847-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-"]}}}]},{"name":"NODE_0000168","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C22739T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179235-"],"OPG038":["E141K"]},"labels":{"aa":"OPG038: E141K"}},"children":[{"name":"OP019276","node_attrs":{"div":63,"accession":"OP019276","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Austria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMPXV/Austria/MUW1527495/2022"},"date":{"value":"2022-06-21"},"strain_display":{"value":"Austria/OP019276/2022-06-21"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP018589","node_attrs":{"div":65,"accession":"OP018589","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/RKI180"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OP018589/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C144256T","G170785A"],"OPG198":["E250K"]},"labels":{"aa":"OPG198: E250K"}}},{"name":"ON808413","node_attrs":{"div":63,"accession":"ON808413","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"lineage":{"value":"B.1.1"},"strain":{"value":"CVR_MPXV1a"},"date":{"value":"2022-05-15"},"strain_display":{"value":"United Kingdom/ON808413/2022-05-15"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP245355","node_attrs":{"div":66,"accession":"OP245355","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPX/PT0122/2022"},"date":{"value":"2022-07-15"},"strain_display":{"value":"Portugal/OP245355/2022-07-15"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G11267A","G18540A","G173727A"],"OPG023":["S545L"],"OPG031":["R97W"]},"labels":{"aa":"OPG023: S545L; OPG031: R97W"}}},{"name":"OP415188","node_attrs":{"div":64,"accession":"OP415188","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPX_dDDHx_9000207"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"United Kingdom/OP415188/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T33222-","A33223-","T33224-","T33225-","C33226-","T33227-","C33228-","A33229-","T33230-","T33231-","G33232-","C33233-","T33234-","T33235-","C144199T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG050":["S59-","N60-","E61-","N62-","I63-"]},"labels":{"aa":"OPG050: S59-, N60-, E61-, N62-, I63-"}}},{"name":"OP524005","node_attrs":{"div":63,"accession":"OP524005","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/RKI400"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP524005/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OR449685","node_attrs":{"div":65,"accession":"OR449685","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI971"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449685/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","C186124T","C189996T"],"OPG193":["F263-"],"OPG210":["S1590F"]},"labels":{"aa":"OPG193: F263-; OPG210: S1590F"}}},{"name":"NODE_0000169","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C22740T","C38937T"],"OPG056":["R33Q"]},"labels":{"aa":"OPG056: R33Q"}},"children":[{"name":"OP555641","node_attrs":{"div":67,"accession":"OP555641","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.1"},"strain":{"value":"Monkeypox/PT0570/2022"},"date":{"value":"2022-09-02"},"strain_display":{"value":"Portugal/OP555641/2022-09-02"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G74362A","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","T136555-","A136556-","T136557-","G136558-","A136559-","T136560-","A136561-","T136562-","C136563-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","C177240T"],"OPG094":["A195T"],"OPG153":["I370-","I371-","D372-","D373-","D374-","D375-","D376-","D377-"],"OPG205":["Q529*"]},"labels":{"aa":"OPG094: A195T; OPG153: I370-, I371-, D372-, D373-, D374-, D375-, D376-, D377-; OPG205: Q529*"}}},{"name":"OP555587","node_attrs":{"div":66,"accession":"OP555587","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.1"},"strain":{"value":"Monkeypox/PT0516/2022"},"date":{"value":"2022-08-17"},"strain_display":{"value":"Portugal/OP555587/2022-08-17"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G778-","T779-","C118523T","A196656-","A196657-"]}}}]}]}]},{"name":"NODE_0000170","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","G190660A"],"OPG016":["R84K"]},"labels":{"aa":"OPG016: R84K","clade":"B.1.3"}},"children":[{"name":"ON983168","node_attrs":{"div":62,"accession":"ON983168","author":{"author":"Chmel,M.,Pajer,P.,Nagy,A.,Zlamal,M.,Jirincova,H.,Dresler,J.,Bartos,O.","value":"Chmel,M.,Pajer,P.,Nagy,A.,Zlamal,M.,Jirincova,H.,Dresler,J.,Bartos,O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Czech Republic"},"clade_membership":{"value":"IIb"},"institution":{"value":"Military Heatlh Institute, Military Heatlh Institute in Prague"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPxV/Prague_001/2022/flye_medaka"},"date":{"value":"2022-04-28"},"strain_display":{"value":"Czech Republic/ON983168/2022-04-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T80849-","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP536795","node_attrs":{"div":62,"accession":"OP536795","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.3"},"strain":{"value":"9000421"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP536795/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ721953","node_attrs":{"div":70,"accession":"OQ721953","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Taiwan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/human/Taiwan/110-525030/2023"},"date":{"value":"2023-03-XX"},"strain_display":{"value":"Taiwan/OQ721953/2023-03-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","C64426T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C166940T","T177665A","A177666T","A177667T","G178104T","G178290T","T178629A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","G196412A"],"OPG205":["N670K","N671F"]},"labels":{"aa":"OPG205: N670K, N671F"}}},{"name":"OR449633","node_attrs":{"div":62,"accession":"OR449633","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/ON/RKI919"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449633/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"NODE_0000171","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["C17196T","C39898T","C148933T","G171318A","C175241T","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG057":["D100N"],"OPG174":["E155K"],"OPG199":["E111K"],"OPG204":["S237L"]},"labels":{"aa":"OPG057: D100N; OPG174: E155K; OPG199: E111K; OPG204: S237L"}},"children":[{"name":"OP205116","node_attrs":{"div":67,"accession":"OP205116","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_UK_2022_9000158"},"date":{"value":"2022-07-07"},"strain_display":{"value":"United Kingdom/OP205116/2022-07-07"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP536779","node_attrs":{"div":67,"accession":"OP536779","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.3"},"strain":{"value":"9000403"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536779/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","A62041-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"]}}}]},{"name":"NODE_0000172","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["G55133A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"],"OPG074":["R665C"]},"labels":{"aa":"OPG074: R665C"}},"children":[{"name":"OQ581854","node_attrs":{"div":65,"accession":"OQ581854","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Taiwan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/human/Taiwan/109-005210/2023"},"date":{"value":"2023-02-XX"},"strain_display":{"value":"Taiwan/OQ581854/2023-02-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G152776A","G158406A","A192404-","G192405-","T192406-","A192411-"],"OPG180":["D29N"]},"labels":{"aa":"OPG180: D29N"}}},{"name":"NODE_0000173","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["C64426T"]}},"children":[{"name":"ON782055","node_attrs":{"div":66,"accession":"ON782055","author":{"author":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Spain"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0001b/2022"},"date":{"value":"2022-05-31"},"strain_display":{"value":"Spain/ON782055/2022-05-31"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A48265T","C48296G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG068":["D22V"]},"labels":{"aa":"OPG068: D22V"}}},{"name":"ON792320","node_attrs":{"div":65,"accession":"ON792320","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Switzerland"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"lineage":{"value":"B.1.3"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba6449f/2022"},"date":{"value":"2022-06-01"},"strain_display":{"value":"Switzerland/ON792320/2022-06-01"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G159376A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG185":["D154N"]},"labels":{"aa":"OPG185: D154N"}}},{"name":"ON754984","node_attrs":{"div":64,"accession":"ON754984","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_SI2022_S3"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Slovenia/ON754984/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A240-","-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON622722","node_attrs":{"div":65,"accession":"ON622722","outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"Virology, GENomique EPIdemiologique das maladies Infectieuses, France"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_FR_HCL0001_2022"},"date":{"value":"2022-05-22"},"strain_display":{"value":"France/ON622722/2022-05-22"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C109627A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG129":["A460S"]},"labels":{"aa":"OPG129: A460S"}}},{"name":"ON609725","node_attrs":{"div":65,"accession":"ON609725","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Skubic,C.,Rozman,D.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Skubic,C.,Rozman,D.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia"},"lineage":{"value":"B.1.3"},"strain":{"value":"SLO"},"date":{"value":"2022-05-23"},"strain_display":{"value":"Slovenia/ON609725/2022-05-23"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T157-","-607T","G167517A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG193":["E62K"]},"labels":{"aa":"OPG193: E62K"}}},{"name":"OP205133","node_attrs":{"div":65,"accession":"OP205133","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_UK_2022_9000188"},"date":{"value":"2022-06-29"},"strain_display":{"value":"United Kingdom/OP205133/2022-06-29"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","C142545T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG163":["S115F"]},"labels":{"aa":"OPG163: S115F"}}},{"name":"OP205067","node_attrs":{"div":64,"accession":"OP205067","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_UK_2022_9000061"},"date":{"value":"2022-05-27"},"strain_display":{"value":"United Kingdom/OP205067/2022-05-27"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OP523994","node_attrs":{"div":67,"accession":"OP523994","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/RKI392"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP523994/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G36659A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G174642A","C190444T"],"OPG016":["S12L"],"OPG055":["A142V"],"OPG204":["M37I"]},"labels":{"aa":"OPG016: S12L; OPG055: A142V; OPG204: M37I"}}},{"name":"OP555633","node_attrs":{"div":65,"accession":"OP555633","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.3"},"strain":{"value":"Monkeypox/PT0562/2022"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Portugal/OP555633/2022-09-01"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168066T"],"OPG153":["D385-"],"OPG193":["Q245*"]},"labels":{"aa":"OPG153: D385-; OPG193: Q245*"}}},{"name":"OP555595","node_attrs":{"div":64,"accession":"OP555595","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.3"},"strain":{"value":"Monkeypox/PT0524/2022"},"date":{"value":"2022-08-18"},"strain_display":{"value":"Portugal/OP555595/2022-08-18"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP879736","node_attrs":{"div":64,"accession":"OP879736","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"lineage":{"value":"B.1.3"},"strain":{"value":"NJ-MPXV-017-rep2"},"date":{"value":"2022-06-29"},"strain_display":{"value":"USA/OP879736/2022-06-29"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ274889","node_attrs":{"div":64,"accession":"OQ274889","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/ON/RKI670"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ274889/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OP894031","node_attrs":{"div":68,"accession":"OP894031","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/ON/RKI611"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP894031/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133094-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","G144669A","G145790A","G168044A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","G181052-","C182177T"],"OPG209":["G179-"]},"labels":{"aa":"OPG209: G179-"}}},{"name":"OQ451904","node_attrs":{"div":76,"accession":"OQ451904","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2023/RKI719"},"date":{"value":"2023-01-XX"},"strain_display":{"value":"Germany/OQ451904/2023-01-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","C15969T","C17998T","G40610A","C43803T","C63879T","G70190A","G118289A","C147011T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G152776A","C159532T","G161629A","C189427T"],"OPG005":["P77S"],"OPG027":["E137K"],"OPG031":["M277I"],"OPG064":["G699E"],"OPG083":["D280N"],"OPG089":["E109K"],"OPG180":["D29N"],"OPG185":["P206S"],"OPG188":["E12K"]},"labels":{"aa":"OPG005: P77S; OPG027: E137K; OPG031: M277I; OPG064: G699E; OPG083: D280N; OPG089: E109K; OPG180: D29N; OPG185: P206S; OPG188: E12K"}}},{"name":"OR035715","node_attrs":{"div":64,"accession":"OR035715","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/UZ_REGA_109"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035715/2022-10-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"]}}},{"name":"OR035686","node_attrs":{"div":65,"accession":"OR035686","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/UZ_REGA_80"},"date":{"value":"2022-08-09"},"strain_display":{"value":"Belgium/OR035686/2022-08-09"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C22950T","T133101-","T133102-","C133161T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ773470","node_attrs":{"div":64,"accession":"OQ773470","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/ON/RKI851"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773470/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-"]}}},{"name":"OR353541","node_attrs":{"div":66,"accession":"OR353541","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Minnesota Department of Health, Public Health Laboratory"},"lineage":{"value":"B.1.3"},"strain":{"value":"MN-MDH-MPXV_0031"},"date":{"value":"2022-07-28"},"strain_display":{"value":"USA/OR353541/2022-07-28"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G13224A","G100344C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG024":["S2L"]},"labels":{"aa":"OPG024: S2L"}}},{"name":"OR264391","node_attrs":{"div":64,"accession":"OR264391","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.3"},"strain":{"value":"2_A"},"date":{"value":"2022-08-10"},"strain_display":{"value":"Australia/OR264391/2022-08-10"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T80846-","T80847-","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OR134560","node_attrs":{"div":75,"accession":"OR134560","author":{"author":"Miller,H.,Bajwa,M.","value":"Miller,H.,Bajwa,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Delaware Public Health Lab, Sequencing/Bioinformatics"},"lineage":{"value":"B.1.3"},"strain":{"value":"B1221136"},"date":{"value":"2023-03-13"},"strain_display":{"value":"USA/OR134560/2023-03-13"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C19558T","G32277A","C35688T","G39140A","G55059A","G75512A","C110402T","C121161T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C170673T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179542T","C189174T"],"OPG034":["E150K"],"OPG049":["S292L"],"OPG073":["S28L"],"OPG095":["R237K"],"OPG139":["A70T"]},"labels":{"aa":"OPG034: E150K; OPG049: S292L; OPG073: S28L; OPG095: R237K; OPG139: A70T"}}},{"name":"OX248696","node_attrs":{"div":66,"accession":"OX248696","outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovakia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"lineage":{"value":"B.1.3"},"strain":{"value":"RNA"},"date":{"value":"2022-07-04"},"strain_display":{"value":"Slovakia/OX248696/2022-07-04"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","G37250A","C138080T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG155":["E138K"]},"labels":{"aa":"OPG155: E138K"}}},{"name":"OR759179","node_attrs":{"div":66,"accession":"OR759179","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.3"},"strain":{"value":"hMpxV/Canada/ON-PHOL091/2022"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759179/2022-09-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G85581A","C122502T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG107":["V24I"],"OPG143":["D272N"]},"labels":{"aa":"OPG107: V24I; OPG143: D272N"}}},{"name":"OP431827","node_attrs":{"div":64,"accession":"OP431827","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV22/human/USA-NE-176"},"date":{"value":"2022-08-15"},"strain_display":{"value":"USA/OP431827/2022-08-15"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"ON782021","node_attrs":{"div":64,"accession":"ON782021","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Finland"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPX-37/Finland/2022"},"date":{"value":"2022-05-24"},"strain_display":{"value":"Finland/ON782021/2022-05-24"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ626769","node_attrs":{"div":64,"accession":"OQ626769","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV22/human/USA-NE-250"},"date":{"value":"2022-09-01"},"strain_display":{"value":"USA/OQ626769/2022-09-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000174","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["T133102-","T168120C","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG193":["F263L"]},"labels":{"aa":"OPG193: F263L"}},"children":[{"name":"OP144212","node_attrs":{"div":66,"accession":"OP144212","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/ITM_pt_16/Belgium/10-Jun-2022"},"date":{"value":"2022-06-10"},"strain_display":{"value":"Belgium/OP144212/2022-06-10"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C133161T","C146824T","C157632T","T197000-"]}}},{"name":"ON950045","node_attrs":{"div":65,"accession":"ON950045","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,Van den Bossche,D.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Van Esbroeck,M.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,Van den Bossche,D.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Van Esbroeck,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/ITM_pt_31/Belgium/27-May-2022"},"date":{"value":"2022-05-27"},"strain_display":{"value":"Belgium/ON950045/2022-05-27"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A140104-","A140105-","T140106-","A140107-","A140108-","C140109-","A140110-","A140111-","T140112-","T140113-","A140114-","T140115-","A140116-","A140117-","C140118-","A140119-","A140120-","T140121-","T140122-","A140123-","T140124-","A140125-","A140126-","C140127-","A140128-","A140129-","T140130-","T140131-","A140132-","T140133-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","A140143-","A140144-","T140145-","T140146-","G140147-","T140148-","T140149-","A140150-","T140151-","A140152-","A140153-","T140154-","A140155-","A140156-","T140157-","T140158-","A140159-","T140160-","A140161-","A140162-","T140163-","T140164-","G140165-","T140166-","T140167-","-196615A"],"OPG159":["N113-","N114-","N115-","Y116-","N117-","N118-","Y119-","N120-","N121-","Y122-","N123-","N124-","Y125-","N126-","C127-","Y128-","N129-","N130-","Y131-","N132-","C133-","Y134-"]},"labels":{"aa":"OPG159: N113-, N114-, N115-, Y116-, N117-, N118-, Y119-, N120-, N121-, Y122-, N123-, N124-, Y125-, N126-, C127-, Y128-, N129-, N130-, Y131-, N132-, C133-, Y134-"}}}]},{"name":"NODE_0000175","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["C133161T","C157632T"]}},"children":[{"name":"OP555472","node_attrs":{"div":66,"accession":"OP555472","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.3"},"strain":{"value":"Monkeypox/PT0376/2022"},"date":{"value":"2022-07-07"},"strain_display":{"value":"Portugal/OP555472/2022-07-07"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159243A"]}}},{"name":"OR086974","node_attrs":{"div":66,"accession":"OR086974","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/UZ_REGA_165/Belgium/2022"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR086974/2022-07-27"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G41336A","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000176","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["-607T","C8612T","C56018T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G187156A"],"OPG074":["E370K"]},"labels":{"aa":"OPG074: E370K"}},"children":[{"name":"OP605585","node_attrs":{"div":68,"accession":"OP605585","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"lineage":{"value":"B.1.3"},"strain":{"value":"Slovenia-MPXV-44-2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Slovenia/OP605585/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G52232A"],"OPG071":["S736L"]},"labels":{"aa":"OPG071: S736L"}}},{"name":"OP605570","node_attrs":{"div":67,"accession":"OP605570","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"lineage":{"value":"B.1.3"},"strain":{"value":"Slovenia-MPXV-28-2022"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Slovenia/OP605570/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000179","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["G105923A","-150590G","-150593G","-150594G","-150599G","-150602G"],"OPG124":["L16F"]},"labels":{"aa":"OPG124: L16F","clade":"C.1"}},"children":[{"name":"LC753968","node_attrs":{"div":65,"accession":"LC753968","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Japan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220165"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Japan/LC753968/2022-09-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}}},{"name":"LC753969","node_attrs":{"div":65,"accession":"LC753969","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Japan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220176"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"Japan/LC753969/2022-10-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}}},{"name":"OR035728","node_attrs":{"div":66,"accession":"OR035728","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/UZ_REGA_122"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035728/2022-10-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G149818A","G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG176":["D4N"]},"labels":{"aa":"OPG176: D4N"}}},{"name":"OQ581853","node_attrs":{"div":67,"accession":"OQ581853","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Taiwan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Taiwan/110-093831/2023"},"date":{"value":"2023-02-XX"},"strain_display":{"value":"Taiwan/OQ581853/2023-02-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T132513C","G150590-","G150593-","G150594-","G150599-","G150602-","C185069T"]}}},{"name":"NODE_0000180","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["C166940T","G193223A"]}},"children":[{"name":"OQ721952","node_attrs":{"div":73,"accession":"OQ721952","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Taiwan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Taiwan/240031000030/2023"},"date":{"value":"2023-03-XX"},"strain_display":{"value":"Taiwan/OQ721952/2023-03-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C798T","C13503T","G33539A","G34948A","G40174A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G156025A","A183935G","A184219G"],"OPG025":["A589T"],"OPG054":["A350V"],"OPG057":["P8S"],"OPG210":["I860M","Y955C"]},"labels":{"aa":"OPG025: A589T; OPG054: A350V; OPG057: P8S; OPG210: I860M, Y955C"}}},{"name":"NODE_0000181","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["C3987T"]}},"children":[{"name":"LC756924","node_attrs":{"div":68,"accession":"LC756924","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Japan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220325"},"date":{"value":"2023-01-30"},"strain_display":{"value":"Japan/LC756924/2023-01-30"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C151434T"]}}},{"name":"LC760461","node_attrs":{"div":68,"accession":"LC760461","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Japan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220343"},"date":{"value":"2023-02-13"},"strain_display":{"value":"Japan/LC760461/2023-02-13"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C798T","C68765T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G196412A"],"OPG086":["M33I"]},"labels":{"aa":"OPG086: M33I"}}},{"name":"OR427348","node_attrs":{"div":70,"accession":"OR427348","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"C.1"},"strain":{"value":"MpxV/human/USA/WA-UW-066957/2023"},"date":{"value":"2023-06-XX"},"strain_display":{"value":"USA/OR427348/2023-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G26855A","C30191T","G150590-","G150593-","G150594-","G150599-","G150602-","C155490T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG047":["R335H"]},"labels":{"aa":"OPG047: R335H"}}},{"name":"OR665166","node_attrs":{"div":72,"accession":"OR665166","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"C.1"},"strain":{"value":"MpxV/human/USA/WA-UW-092809/2023"},"date":{"value":"2023-09-XX"},"strain_display":{"value":"USA/OR665166/2023-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","G13434A","G29650A","C33332T","G37974A","C74691T","G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG025":["R612C"],"OPG046":["T27I"],"OPG050":["R26Q"],"OPG056":["S354L"]},"labels":{"aa":"OPG025: R612C; OPG046: T27I; OPG050: R26Q; OPG056: S354L"}}},{"name":"OR499979","node_attrs":{"div":70,"accession":"OR499979","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00522/2023"},"date":{"value":"2023-05-08"},"strain_display":{"value":"USA/OR499979/2023-05-08"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G11924A","C134237T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G178951A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG023":["S326L"]},"labels":{"aa":"OPG023: S326L"}}},{"name":"OR459797","node_attrs":{"div":67,"accession":"OR459797","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"South Korea"},"clade_membership":{"value":"IIb"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV-ROK-P026-2023"},"date":{"value":"2023-04-22"},"strain_display":{"value":"South Korea/OR459797/2023-04-22"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A113921-","G150590-","G150593-","G150594-","G150599-","G150602-","T169716C","G169717A","T169721A","G169775A","T169776C","A169780T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181T","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG197":["M16T","S18T","V36T","E37D"]},"labels":{"aa":"OPG197: M16T, S18T, V36T, E37D"}}},{"name":"NODE_0000182","node_attrs":{"div":69,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["C149963T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G184562A"],"OPG176":["S52L"]},"labels":{"aa":"OPG176: S52L"}},"children":[{"name":"OR459778","node_attrs":{"div":70,"accession":"OR459778","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"South Korea"},"clade_membership":{"value":"IIb"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV-ROK-P005-2023"},"date":{"value":"2023-03-13"},"strain_display":{"value":"South Korea/OR459778/2023-03-13"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G85691A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000183","node_attrs":{"div":72,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["C21062T","G188348A","C188946T"],"OPG036":["M1I"]},"labels":{"aa":"OPG036: M1I"}},"children":[{"name":"OR643705","node_attrs":{"div":78,"accession":"OR643705","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"C.1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00563/2023"},"date":{"value":"2023-08-16"},"strain_display":{"value":"USA/OR643705/2023-08-16"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G21880A","G47532A","C125074T","G133704A","G133838A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T180483A"],"OPG037":["S185F"]},"labels":{"aa":"OPG037: S185F"}}},{"name":"NODE_0000184","node_attrs":{"div":75,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["G101241A","C142797T","G152866A","C191053-","A191054-","T191055-","G191056-","G191057-","A191058-","G191059-","T191060-","C191061-","G191062-","G191063-","T191064-","A191065-","G191066-","A191067-","T191068-","T191069-","T191070-","C191071-","A191072-","T191073-","G191074-","G191075-","C191076-","T191077-","G191078-","T191079-","C191080-","G191081-","A191082-","T191083-","G191084-","A191085-","G191086-","C191087-","A191088-","G191089-","T191090-","T191091-","T191092-","C191093-","A191094-","C191095-","G191096-","A191097-","C191098-","G191099-","A191100-","C191101-","C191102-","T191103-","C191104-","G191105-","A191106-","T191107-","C191108-","T191109-","T191110-","T191111-","G191112-","G191113-","T191114-","C191115-","A191116-","T191117-","T191118-","A191119-","T191120-","C191121-","T191122-","T191123-","T191124-","G191125-","G191126-","T191127-","A191128-","G191129-"],"OPG164":["S7L"],"OPG180":["D59N"]},"labels":{"aa":"OPG164: S7L; OPG180: D59N"}},"children":[{"name":"OR326991","node_attrs":{"div":76,"accession":"OR326991","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/PT0627/2023"},"date":{"value":"2023-06-15"},"strain_display":{"value":"Portugal/OR326991/2023-06-15"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G165862T"]}}},{"name":"OR743499","node_attrs":{"div":77,"accession":"OR743499","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1030"},"date":{"value":"2023-10-XX"},"strain_display":{"value":"Germany/OR743499/2023-10-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T57476C","G173397A","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG075":["Q8R"]},"labels":{"aa":"OPG075: Q8R"}}},{"name":"OR519724","node_attrs":{"div":75,"accession":"OR519724","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1022"},"date":{"value":"2023-08-XX"},"strain_display":{"value":"Germany/OR519724/2023-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"]}}},{"name":"OR487998","node_attrs":{"div":76,"accession":"OR487998","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/PT0680/2023"},"date":{"value":"2023-08-08"},"strain_display":{"value":"Portugal/OR487998/2023-08-08"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A176268G"],"OPG205":["S205G"]},"labels":{"aa":"OPG205: S205G"}}},{"name":"OR487980","node_attrs":{"div":78,"accession":"OR487980","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/PT0656/2023"},"date":{"value":"2023-07-21"},"strain_display":{"value":"Portugal/OR487980/2023-07-21"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","G13563A","C37738T","G151847A","A196614-"],"OPG025":["P569S"],"OPG056":["E433K"]},"labels":{"aa":"OPG025: P569S; OPG056: E433K"}}}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}} diff --git a/data/nextstrain/mpox/lineage-b.1/CHANGELOG.md b/data/nextstrain/mpox/lineage-b.1/CHANGELOG.md new file mode 100644 index 00000000..f941baec --- /dev/null +++ b/data/nextstrain/mpox/lineage-b.1/CHANGELOG.md @@ -0,0 +1,13 @@ +## Unreleased + +Initial release of this dataset. This dataset is similar to the v2 dataset [`hMPXV_B.1/pseudo_ON563414`](https://github.com/nextstrain/nextclade_data/tree/2023-08-17--15-51-24--UTC/data/datasets/hMPXV_B.1/references/pseudo_ON563414/versions/2023-08-01T12%3A00%3A00Z/files) with some differences. + +### New and changed gene names + +Some genes have been renamed and one has been added. The new annotation is based on NCBI refseq annotations that were released in November 2022. The v2 dataset predates this refseq: + +- The 4 genes in the inverted terminal repeat segment (ITR) on both ends of the genome (OPG001, OPG002, OPG003,OPG015) are now all included. The genes on the 3' end (~positions 190000-197000) now have an `_dup` appended to distinguish them. +- The gene previously named `NBT03_gp052` is now called `OPG073` +- The gene previously named `NBT03_gp174` is now called `OPG016` +- The gene previously named `NBT03_gp175` is now called `OPG015_dup` +- Gene `OPG166` has been added diff --git a/data/nextstrain/mpox/lineage-b.1/README.md b/data/nextstrain/mpox/lineage-b.1/README.md new file mode 100644 index 00000000..2cb8b770 --- /dev/null +++ b/data/nextstrain/mpox/lineage-b.1/README.md @@ -0,0 +1,24 @@ +# Nextclade dataset for "Mpox virus (Lineage B.1)" + +| Key | Value | +| ---------------------- | --------------------------------------------------------------------------------------------------------------------- | +| authors | [Cornelius Roemer](https://neherlab.org), [Richard Neher](https://neherlab.org), [Nextstrain](https://nextstrain.org) | +| data source | Genbank | +| workflow | [github.com/nextstrain/mpox/nextclade](https://github.com/nextstrain/mpox/nextclade) | +| nextclade dataset path | nextstrain/mpox/lineage-b.1 | +| annotation | [NC_063383.1](https://www.ncbi.nlm.nih.gov/nuccore/NC_063383) | +| clade definitions | [github.com/mpxv-lineages/lineage-designation](https://github.com/mpxv-lineages/lineage-designation) | +| related datasets | Mpox virus (All clades): `nextstrain/mpox/all-clades`
Mpox virus (Clade IIb) `nextstrain/mpox/clade-iib` | + +This dataset is for Mpox viruses of the 2022-2023 outbreak lineage B.1. Two broader datasets for clade IIb and all clades are available as well: `nextstrain/mpox/clade-iib` for Clade IIb and `nextstrain/mpox/all-clades` for all clades (I, IIa and IIb). + +The lineage system used is defined in [Happi et al. (2022)](https://doi.org/10.1371/journal.pbio.3001769). Lineage definitions are available at [github.com/mpxv-lineages/lineage-designation](https://github.com/nextstrain/mpox/nextclade). + +The reference used in this dataset is the clade IIb NCBI refseq `NC_063383.1` (Isolate `MPXV-M5312_HM12_Rivers`) with all B.1 defining SNPs added to make the mutation view less cluttered. + +The reference tree consists of around 1000 sequences with representatives from all B.1 sublineages. + + +## Further reading + +Read more about Nextclade datasets in Nextclade documentation: https://docs.nextstrain.org/projects/nextclade/en/stable/user/datasets.html diff --git a/data/nextstrain/mpox/lineage-b.1/genome_annotation.gff3 b/data/nextstrain/mpox/lineage-b.1/genome_annotation.gff3 new file mode 100644 index 00000000..432d5465 --- /dev/null +++ b/data/nextstrain/mpox/lineage-b.1/genome_annotation.gff3 @@ -0,0 +1,391 @@ +##gff-version 3 +#!gff-spec-version 1.21 +#!processor NCBI annotwriter +##sequence-region NC_063383.1 1 197209 +##species https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10244 +NC_063383.1 RefSeq region 1 197209 . + . ID=NC_063383.1:1..197209;Dbxref=taxon:10244;collection-date=2018-08;country=Nigeria: Rivers State;gbkey=Src;genome=genomic;genotype=MPXV clade 2;isolate=MPXV-M5312_HM12_Rivers;mol_type=genomic DNA;nat-host=Homo sapiens +NC_063383.1 RefSeq long_terminal_repeat 1 6422 . - . ID=id-NC_063383.1:1..6422;gbkey=repeat_region;rpt_type=long_terminal_repeat +NC_063383.1 RefSeq gene 835 1575 . - . ID=gene-NBT03_gp001;Dbxref=GeneID:72551607;Name=OPG001;gbkey=Gene;gene=OPG001;gene_biotype=protein_coding;locus_tag=NBT03_gp001;old_locus_tag=MPXV-M5312_HM12_Rivers-001 +NC_063383.1 RefSeq CDS 835 1575 . - 0 ID=cds-YP_010377002.1;Parent=gene-NBT03_gp001;Dbxref=GenBank:YP_010377002.1,GeneID:72551607;Name=OPG001;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp001%3B Chemokine binding protein (Cop-C23L)%3B most abundant secreted protein%3B CC-chemokine binding%3B similar to VACV-WR J1L and VACV-Cop C23L;gbkey=CDS;gene=OPG001;locus_tag=NBT03_gp001;product=Chemokine binding protein;protein_id=YP_010377002.1 +NC_063383.1 RefSeq gene 1702 2751 . - . ID=gene-NBT03_gp002;Dbxref=GeneID:72551418;Name=OPG002;gbkey=Gene;gene=OPG002;gene_biotype=protein_coding;locus_tag=NBT03_gp002;old_locus_tag=MPXV-M5312_HM12_Rivers-002 +NC_063383.1 RefSeq CDS 1702 2751 . - 0 ID=cds-YP_010377003.1;Parent=gene-NBT03_gp002;Dbxref=GenBank:YP_010377003.1,GeneID:72551418;Name=OPG002;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: NBT03_gp002%3B TNF receptor (CrmB)%3B similar to VACV-WR J2L and VACV-Cop C22L;gbkey=CDS;gene=OPG002;locus_tag=NBT03_gp002;product=Crm-B secreted TNF-alpha-receptor-like protein;protein_id=YP_010377003.1 +NC_063383.1 RefSeq gene 2841 4607 . - . ID=gene-NBT03_gp003;Dbxref=GeneID:72551419;Name=OPG003;gbkey=Gene;gene=OPG003;gene_biotype=protein_coding;locus_tag=NBT03_gp003;old_locus_tag=MPXV-M5312_HM12_Rivers-003 +NC_063383.1 RefSeq CDS 2841 4607 . - 0 ID=cds-YP_010377004.1;Parent=gene-NBT03_gp003;Dbxref=GenBank:YP_010377004.1,GeneID:72551419;Name=OPG003;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp003%3B Ankyrin%3B similar to VACV-WR J3L and VACV-Cop C19L;gbkey=CDS;gene=OPG003;locus_tag=NBT03_gp003;product=Ankyrin repeat protein (25);protein_id=YP_010377004.1 +NC_063383.1 RefSeq gene 4843 6156 . - . ID=gene-NBT03_gp004;Dbxref=GeneID:72551420;Name=OPG015;gbkey=Gene;gene=OPG015;gene_biotype=protein_coding;locus_tag=NBT03_gp004;old_locus_tag=MPXV-M5312_HM12_Rivers-004 +NC_063383.1 RefSeq CDS 4843 6156 . - 0 ID=cds-YP_010377005.1;Parent=gene-NBT03_gp004;Dbxref=GenBank:YP_010377005.1,GeneID:72551420;Name=OPG015;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp004%3B Ankyrin%3B similar to VACV-WR D1L and CPXV-017;gbkey=CDS;gene=OPG015;locus_tag=NBT03_gp004;product=Ankyrin repeat protein (39);protein_id=YP_010377005.1 +NC_063383.1 RefSeq sequence_feature 6270 6419 . - . ID=id-NC_063383.1:6270..6419;exon_number=OPG016;gbkey=misc_feature;number=OPG016 +NC_063383.1 RefSeq sequence_feature 6444 6885 . - . ID=id-NC_063383.1:6444..6885;exon_number=OPG017;gbkey=misc_feature;number=OPG017 +NC_063383.1 RefSeq sequence_feature 6966 7463 . - . ID=id-NC_063383.1:6966..7463;exon_number=OPG018;gbkey=misc_feature;number=OPG018 +NC_063383.1 RefSeq gene 7580 8008 . + . ID=gene-NBT03_gp005;Dbxref=GeneID:72551421;Name=OPG019;gbkey=Gene;gene=OPG019;gene_biotype=protein_coding;locus_tag=NBT03_gp005;old_locus_tag=MPXV-M5312_HM12_Rivers-006 +NC_063383.1 RefSeq CDS 7580 8008 . + 0 ID=cds-YP_010377006.1;Parent=gene-NBT03_gp005;Dbxref=GenBank:YP_010377006.1,GeneID:72551421;Name=OPG019;Note=Taxonomic breadth: chordopoxvirinae%3B secreted growth factor Secreted EGF-like protein%3B similar to VACV-WR D3R and VACV-Cop C11R;gbkey=CDS;gene=OPG019;locus_tag=NBT03_gp005;product=EGF-like domain protein;protein_id=YP_010377006.1 +NC_063383.1 RefSeq sequence_feature 8136 9102 . - . ID=id-NC_063383.1:8136..9102;exon_number=OPG020;gbkey=misc_feature;number=OPG020 +NC_063383.1 RefSeq gene 9587 10315 . + . ID=gene-NBT03_gp006;Dbxref=GeneID:72551422;Name=OPG021;gbkey=Gene;gene=OPG021;gene_biotype=protein_coding;locus_tag=NBT03_gp006;old_locus_tag=MPXV-M5312_HM12_Rivers-008 +NC_063383.1 RefSeq CDS 9587 10315 . + 0 ID=cds-YP_010377007.1;Parent=gene-NBT03_gp006;Dbxref=GenBank:YP_010377007.1,GeneID:72551422;Name=OPG021;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp008%3B Zinc finger-like protein%3B zinc binding%3B virosome localization%3B virulence factor%3B inhibition of apoptosis induced by UV irradiation%3B similar to VACV-WR D5R;gbkey=CDS;gene=OPG021;locus_tag=NBT03_gp006;product=Zinc finger-like protein (2);protein_id=YP_010377007.1 +NC_063383.1 RefSeq gene 10478 10858 . - . ID=gene-NBT03_gp007;Dbxref=GeneID:72551423;Name=OPG022;gbkey=Gene;gene=OPG022;gene_biotype=protein_coding;locus_tag=NBT03_gp007;old_locus_tag=MPXV-M5312_HM12_Rivers-009 +NC_063383.1 RefSeq CDS 10478 10858 . - 0 ID=cds-YP_010377008.1;Parent=gene-NBT03_gp007;Dbxref=GenBank:YP_010377008.1,GeneID:72551423;Name=OPG022;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp009%3B secreted IL-18 binding protein%3B Soluble IL-18 binding protein (Bsh-D7L)%3B similar to VACV-WR D6L;gbkey=CDS;gene=OPG022;locus_tag=NBT03_gp007;product=Interleukin-18-binding protein;protein_id=YP_010377008.1 +NC_063383.1 RefSeq gene 10918 12900 . - . ID=gene-NBT03_gp008;Dbxref=GeneID:72551424;Name=OPG023;gbkey=Gene;gene=OPG023;gene_biotype=protein_coding;locus_tag=NBT03_gp008;old_locus_tag=MPXV-M5312_HM12_Rivers-010 +NC_063383.1 RefSeq CDS 10918 12900 . - 0 ID=cds-YP_010377009.1;Parent=gene-NBT03_gp008;Dbxref=GenBank:YP_010377009.1,GeneID:72551424;Name=OPG023;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp010%3B host range%3B ankyrin-like%3B Ankyrin/Host Range (Bang-D8L)%3B similar to VACV-WR D7L;gbkey=CDS;gene=OPG023;locus_tag=NBT03_gp008;product=Ankyrin repeat protein (2);protein_id=YP_010377009.1 +NC_063383.1 RefSeq gene 13034 13228 . - . ID=gene-NBT03_gp009;Dbxref=GeneID:72551425;Name=OPG024;gbkey=Gene;gene=OPG024;gene_biotype=protein_coding;locus_tag=NBT03_gp009;old_locus_tag=MPXV-M5312_HM12_Rivers-011 +NC_063383.1 RefSeq CDS 13034 13228 . - 0 ID=cds-YP_010377010.1;Parent=gene-NBT03_gp009;Dbxref=GenBank:YP_010377010.1,GeneID:72551425;Name=OPG024;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp011%3B ANK-containing protein%3B similar to VACV-WR D8L;gbkey=CDS;gene=OPG024;locus_tag=NBT03_gp009;product=retroviral pseudoprotease-like protein;protein_id=YP_010377010.1 +NC_063383.1 RefSeq gene 13375 15267 . - . ID=gene-NBT03_gp010;Dbxref=GeneID:72551426;Name=OPG025;gbkey=Gene;gene=OPG025;gene_biotype=protein_coding;locus_tag=NBT03_gp010;old_locus_tag=MPXV-M5312_HM12_Rivers-012 +NC_063383.1 RefSeq CDS 13375 15267 . - 0 ID=cds-YP_010377011.1;Parent=gene-NBT03_gp010;Dbxref=GenBank:YP_010377011.1,GeneID:72551426;Name=OPG025;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp012%3B ankyrin-like%3B Type I IFN resistance%3B similar to VACV-WR D9L and VACV-Cop C9L;gbkey=CDS;gene=OPG025;locus_tag=NBT03_gp010;product=Ankyrin repeat protein (14);protein_id=YP_010377011.1 +NC_063383.1 RefSeq sequence_feature 15310 15854 . - . ID=id-NC_063383.1:15310..15854;exon_number=OPG026;gbkey=misc_feature;number=OPG026 +NC_063383.1 RefSeq gene 15925 16377 . - . ID=gene-NBT03_gp011;Dbxref=GeneID:72551427;Name=OPG027;gbkey=Gene;gene=OPG027;gene_biotype=protein_coding;locus_tag=NBT03_gp011;old_locus_tag=MPXV-M5312_HM12_Rivers-013 +NC_063383.1 RefSeq CDS 15925 16377 . - 0 ID=cds-YP_010377012.1;Parent=gene-NBT03_gp011;Dbxref=GenBank:YP_010377012.1,GeneID:72551427;Name=OPG027;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp013%3B host range%3B Type 1 IFN inhibitor%3B similar to VACV-WR D10L and VACV-Cop C7L;gbkey=CDS;gene=OPG027;locus_tag=NBT03_gp011;product=Host range protein;protein_id=YP_010377012.1 +NC_063383.1 RefSeq gene 16602 17069 . - . ID=gene-NBT03_gp012;Dbxref=GeneID:72551428;Name=OPG029;gbkey=Gene;gene=OPG029;gene_biotype=protein_coding;locus_tag=NBT03_gp012;old_locus_tag=MPXV-M5312_HM12_Rivers-014 +NC_063383.1 RefSeq CDS 16602 17069 . - 0 ID=cds-YP_010377013.1;Parent=gene-NBT03_gp012;Dbxref=GenBank:YP_010377013.1,GeneID:72551428;Name=OPG029;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp014%3B Putative tlr signaling inhibitor%2C IFN-beta inhibitor%3B similar to VACV-WR D11L and VACV-Cop C6L;gbkey=CDS;gene=OPG029;locus_tag=NBT03_gp012;product=Bcl-2-like protein;protein_id=YP_010377013.1 +NC_063383.1 RefSeq gene 17213 17833 . - . ID=gene-NBT03_gp013;Dbxref=GeneID:72551429;Name=OPG030;gbkey=Gene;gene=OPG030;gene_biotype=protein_coding;locus_tag=NBT03_gp013;old_locus_tag=MPXV-M5312_HM12_Rivers-015 +NC_063383.1 RefSeq CDS 17213 17833 . - 0 ID=cds-YP_010377014.1;Parent=gene-NBT03_gp013;Dbxref=GenBank:YP_010377014.1,GeneID:72551429;Name=OPG030;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp015%3B BTB domain of kelch-like protein%3B Kelch-like protein%3B similar to VACV-WR D12L and VACV-Cop C5L;gbkey=CDS;gene=OPG030;locus_tag=NBT03_gp013;product=Kelch-like protein (1);protein_id=YP_010377014.1 +NC_063383.1 RefSeq gene 17878 18828 . - . ID=gene-NBT03_gp014;Dbxref=GeneID:72551430;Name=OPG031;gbkey=Gene;gene=OPG031;gene_biotype=protein_coding;locus_tag=NBT03_gp014;old_locus_tag=MPXV-M5312_HM12_Rivers-016 +NC_063383.1 RefSeq CDS 17878 18828 . - 0 ID=cds-YP_010377015.1;Parent=gene-NBT03_gp014;Dbxref=GenBank:YP_010377015.1,GeneID:72551430;Name=OPG031;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp016%3B IL-1 receptor antagonist%3B similar to VACV-WR D13L and VACV-Cop C10L;gbkey=CDS;gene=OPG031;locus_tag=NBT03_gp014;product=C4L/C10L-like family protein;protein_id=YP_010377015.1 +NC_063383.1 RefSeq sequence_feature 18902 19288 . - . ID=id-NC_063383.1:18902..19288;exon_number=OPG033;gbkey=misc_feature;number=OPG033 +NC_063383.1 RefSeq gene 19361 20005 . - . ID=gene-NBT03_gp015;Dbxref=GeneID:72551431;Name=OPG034;gbkey=Gene;gene=OPG034;gene_biotype=protein_coding;locus_tag=NBT03_gp015;old_locus_tag=MPXV-M5312_HM12_Rivers-018 +NC_063383.1 RefSeq CDS 19361 20005 . - 0 ID=cds-YP_010377017.1;Parent=gene-NBT03_gp015;Dbxref=GenBank:YP_010377017.1,GeneID:72551431;Name=OPG034;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp022%3B Putative TLR signalling inhibitor%3B start of ORF is missing approx. 18 AA compared to CPXVs%3B similar to VACV-WR D19L and VACV-Cop C1L;gbkey=CDS;gene=OPG034;locus_tag=NBT03_gp015;product=Bcl-2-like protein;protein_id=YP_010377017.1 +NC_063383.1 RefSeq gene 20051 20404 . - . ID=gene-NBT03_gp016;Dbxref=GeneID:72551432;Name=OPG035;gbkey=Gene;gene=OPG035;gene_biotype=protein_coding;locus_tag=NBT03_gp016;old_locus_tag=MPXV-M5312_HM12_Rivers-019 +NC_063383.1 RefSeq CDS 20051 20404 . - 0 ID=cds-YP_010377018.1;Parent=gene-NBT03_gp016;Dbxref=GenBank:YP_010377018.1,GeneID:72551432;Name=OPG035;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp023%3B secreted virulence factor%3B Putative tlr signaling inhibitor%3B Anti-apoptotic Bcl-2-like protein%3B similar to VACV-WR P1L and VACV-Cop N1L;gbkey=CDS;gene=OPG035;locus_tag=NBT03_gp016;product=Bcl-2-like protein;protein_id=YP_010377018.1 +NC_063383.1 RefSeq gene 20531 21064 . - . ID=gene-NBT03_gp017;Dbxref=GeneID:72551433;Name=OPG036;gbkey=Gene;gene=OPG036;gene_biotype=protein_coding;locus_tag=NBT03_gp017;old_locus_tag=MPXV-M5312_HM12_Rivers-020 +NC_063383.1 RefSeq CDS 20531 21064 . - 0 ID=cds-YP_010377019.1;Parent=gene-NBT03_gp017;Dbxref=GenBank:YP_010377019.1,GeneID:72551433;Name=OPG036;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp024%3B Alpha amanatin target protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR P2L and VACV-Cop #N2L;gbkey=CDS;gene=OPG036;locus_tag=NBT03_gp017;product=Bcl-2-like protein;protein_id=YP_010377019.1 +NC_063383.1 RefSeq gene 21105 22433 . - . ID=gene-NBT03_gp018;Dbxref=GeneID:72551434;Name=OPG037;gbkey=Gene;gene=OPG037;gene_biotype=protein_coding;locus_tag=NBT03_gp018;old_locus_tag=MPXV-M5312_HM12_Rivers-021 +NC_063383.1 RefSeq CDS 21105 22433 . - 0 ID=cds-YP_010377020.1;Parent=gene-NBT03_gp018;Dbxref=GenBank:YP_010377020.1,GeneID:72551434;Name=OPG037;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp025%3B ankyrin-like%3B ANK-containing protein%3B apoptosis inhibitor%3B start of ORF is missing approx. 31 AA compared to CPXVs%3B similar to VACV-WR O1L and VACV-Cop M1L;gbkey=CDS;gene=OPG037;locus_tag=NBT03_gp018;product=Ankyrin-like protein (1);protein_id=YP_010377020.1 +NC_063383.1 RefSeq gene 22497 23159 . - . ID=gene-NBT03_gp019;Dbxref=GeneID:72551435;Name=OPG038;gbkey=Gene;gene=OPG038;gene_biotype=protein_coding;locus_tag=NBT03_gp019;old_locus_tag=MPXV-M5312_HM12_Rivers-022 +NC_063383.1 RefSeq CDS 22497 23159 . - 0 ID=cds-YP_010377021.1;Parent=gene-NBT03_gp019;Dbxref=GenBank:YP_010377021.1,GeneID:72551435;Name=OPG038;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp026%3B NFkB inhibitor%3B similar to VACV-WR O2L and VACV-Cop M2L;gbkey=CDS;gene=OPG038;locus_tag=NBT03_gp019;product=NFkB inhibitor;protein_id=YP_010377021.1 +NC_063383.1 RefSeq gene 23264 24118 . - . ID=gene-NBT03_gp020;Dbxref=GeneID:72551436;Name=OPG039;gbkey=Gene;gene=OPG039;gene_biotype=protein_coding;locus_tag=NBT03_gp020;old_locus_tag=MPXV-M5312_HM12_Rivers-023 +NC_063383.1 RefSeq CDS 23264 24118 . - 0 ID=cds-YP_010377022.1;Parent=gene-NBT03_gp020;Dbxref=GenBank:YP_010377022.1,GeneID:72551436;Name=OPG039;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp027%3B host range%3B ankyrin-like%3B Ankyrin/NFkB inhibitor%3B similar to VACV-WR C1L and VACV-Cop K1L;gbkey=CDS;gene=OPG039;locus_tag=NBT03_gp020;product=Ankyrin-like protein (3);protein_id=YP_010377022.1 +NC_063383.1 RefSeq gene 24351 25478 . - . ID=gene-NBT03_gp021;Dbxref=GeneID:72551437;Name=OPG040;gbkey=Gene;gene=OPG040;gene_biotype=protein_coding;locus_tag=NBT03_gp021;old_locus_tag=MPXV-M5312_HM12_Rivers-024 +NC_063383.1 RefSeq CDS 24351 25478 . - 0 ID=cds-YP_010377023.1;Parent=gene-NBT03_gp021;Dbxref=GenBank:YP_010377023.1,GeneID:72551437;Name=OPG040;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp028%3B serine protease inhibitor-like%2C SPI-3%3B inhibition of the ability of infected cells to fuse%3B Serpin 1%2C2%2C3%3B similar to VACV-WR C2L and VACV-Cop K2L;gbkey=CDS;gene=OPG040;locus_tag=NBT03_gp021;product=Serpin;protein_id=YP_010377023.1 +NC_063383.1 RefSeq sequence_feature 25529 25767 . - . ID=id-NC_063383.1:25529..25767;exon_number=OPG041;gbkey=misc_feature;number=OPG041 +NC_063383.1 RefSeq gene 25823 27097 . - . ID=gene-NBT03_gp022;Dbxref=GeneID:72551438;Name=OPG042;gbkey=Gene;gene=OPG042;gene_biotype=protein_coding;locus_tag=NBT03_gp022;old_locus_tag=MPXV-M5312_HM12_Rivers-026 +NC_063383.1 RefSeq CDS 25823 27097 . - 0 ID=cds-YP_010377025.1;Parent=gene-NBT03_gp022;Dbxref=GenBank:YP_010377025.1,GeneID:72551438;Name=OPG042;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp030%3B phospholipase D-like%3B Phospholipase-D-like protein%3B similar to VACV-WR C4L and VACV-Cop K4L;gbkey=CDS;gene=OPG042;locus_tag=NBT03_gp022;product=Phospholipase-D-like protein;protein_id=YP_010377025.1 +NC_063383.1 RefSeq gene 27125 27955 . - . ID=gene-NBT03_gp023;Dbxref=GeneID:72551439;Name=OPG043;gbkey=Gene;gene=OPG043;gene_biotype=protein_coding;locus_tag=NBT03_gp023;old_locus_tag=MPXV-M5312_HM12_Rivers-027 +NC_063383.1 RefSeq CDS 27125 27955 . - 0 ID=cds-YP_010377026.1;Parent=gene-NBT03_gp023;Dbxref=GenBank:YP_010377026.1,GeneID:72551439;Name=OPG043;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp031%3B lysophospholipase-like%3B Monoglyceride lipase%3B similar to VACV-WR C5L and VACV-Cop K5L;gbkey=CDS;gene=OPG043;locus_tag=NBT03_gp023;product=Putative monoglyceride lipase;protein_id=YP_010377026.1 +NC_063383.1 RefSeq gene 28091 28540 . + . ID=gene-NBT03_gp024;Dbxref=GeneID:72551440;Name=OPG044;gbkey=Gene;gene=OPG044;gene_biotype=protein_coding;locus_tag=NBT03_gp024;old_locus_tag=MPXV-M5312_HM12_Rivers-028 +NC_063383.1 RefSeq CDS 28091 28540 . + 0 ID=cds-YP_010377027.1;Parent=gene-NBT03_gp024;Dbxref=GenBank:YP_010377027.1,GeneID:72551440;Name=OPG044;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp032%3B Putative tlr signaling inhibitor%3B Host immune response repressor%3B similar to VACV-WR C6R and VACV-Cop #K7R;gbkey=CDS;gene=OPG044;locus_tag=NBT03_gp024;product=Bcl-2-like protein;protein_id=YP_010377027.1 +NC_063383.1 RefSeq gene 28603 29262 . - . ID=gene-NBT03_gp025;Dbxref=GeneID:72551441;Name=OPG045;gbkey=Gene;gene=OPG045;gene_biotype=protein_coding;locus_tag=NBT03_gp025;old_locus_tag=MPXV-M5312_HM12_Rivers-029 +NC_063383.1 RefSeq CDS 28603 29262 . - 0 ID=cds-YP_010377028.1;Parent=gene-NBT03_gp025;Dbxref=GenBank:YP_010377028.1,GeneID:72551441;Name=OPG045;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp033%3B Caspase-9 (apoptosis) inhibitor (mitochondrial- associated)%3B similar to VACV-WR C7L and VACV-Cop F1L;gbkey=CDS;gene=OPG045;locus_tag=NBT03_gp025;product=Caspase-9 inhibitor;protein_id=YP_010377028.1 +NC_063383.1 RefSeq gene 29274 29729 . - . ID=gene-NBT03_gp026;Dbxref=GeneID:72551442;Name=OPG046;gbkey=Gene;gene=OPG046;gene_biotype=protein_coding;locus_tag=NBT03_gp026;old_locus_tag=MPXV-M5312_HM12_Rivers-030 +NC_063383.1 RefSeq CDS 29274 29729 . - 0 ID=cds-YP_010377029.1;Parent=gene-NBT03_gp026;Dbxref=GenBank:YP_010377029.1,GeneID:72551442;Name=OPG046;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp034%3B deoxyuridine triphosphatase%3B dUTPase%3B similar to VACV-WR C8L and VACV-Cop F2L;gbkey=CDS;gene=OPG046;locus_tag=NBT03_gp026;product=dUTPase;protein_id=YP_010377029.1 +NC_063383.1 RefSeq gene 29746 31194 . - . ID=gene-NBT03_gp027;Dbxref=GeneID:72551443;Name=OPG047;gbkey=Gene;gene=OPG047;gene_biotype=protein_coding;locus_tag=NBT03_gp027;old_locus_tag=MPXV-M5312_HM12_Rivers-031 +NC_063383.1 RefSeq CDS 29746 31194 . - 0 ID=cds-YP_010377030.1;Parent=gene-NBT03_gp027;Dbxref=GenBank:YP_010377030.1,GeneID:72551443;Name=OPG047;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp035%3B kelch-like%3B Kelch-like protein%3B similar to VACV-WR C9L and VACV-Cop F3L;gbkey=CDS;gene=OPG047;locus_tag=NBT03_gp027;product=Kelch-like protein (2);protein_id=YP_010377030.1 +NC_063383.1 RefSeq gene 31205 32164 . - . ID=gene-NBT03_gp028;Dbxref=GeneID:72551444;Name=OPG048;gbkey=Gene;gene=OPG048;gene_biotype=protein_coding;locus_tag=NBT03_gp028;old_locus_tag=MPXV-M5312_HM12_Rivers-032 +NC_063383.1 RefSeq CDS 31205 32164 . - 0 ID=cds-YP_010377031.1;Parent=gene-NBT03_gp028;Dbxref=GenBank:YP_010377031.1,GeneID:72551444;Name=OPG048;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp036%3B Ribonucleotide reductase small subunit%2C R2%3B similar to VACV-WR C10L and VACV-Cop F4L;gbkey=CDS;gene=OPG048;locus_tag=NBT03_gp028;product=Ribonucleotide reductase small subunit;protein_id=YP_010377031.1 +NC_063383.1 RefSeq gene 32195 33151 . - . ID=gene-NBT03_gp029;Dbxref=GeneID:72551445;Name=OPG049;gbkey=Gene;gene=OPG049;gene_biotype=protein_coding;locus_tag=NBT03_gp029;old_locus_tag=MPXV-M5312_HM12_Rivers-033 +NC_063383.1 RefSeq CDS 32195 33151 . - 0 ID=cds-YP_010377032.1;Parent=gene-NBT03_gp029;Dbxref=GenBank:YP_010377032.1,GeneID:72551445;Name=OPG049;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp037%3B 36kDa major membrane protein%3B similar to VACV-WR C11L and VACV-Cop F5L;gbkey=CDS;gene=OPG049;locus_tag=NBT03_gp029;product=Telomere-binding protein I6 (1);protein_id=YP_010377032.1 +NC_063383.1 RefSeq gene 33181 33408 . - . ID=gene-NBT03_gp030;Dbxref=GeneID:72551446;Name=OPG050;gbkey=Gene;gene=OPG050;gene_biotype=protein_coding;locus_tag=NBT03_gp030;old_locus_tag=MPXV-M5312_HM12_Rivers-034 +NC_063383.1 RefSeq CDS 33181 33408 . - 0 ID=cds-YP_010377033.1;Parent=gene-NBT03_gp030;Dbxref=GenBank:YP_010377033.1,GeneID:72551446;Name=OPG050;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp038%3B Hypothetical protein%3B similar to VACV-WR C12L and VACV-Cop F6L;gbkey=CDS;gene=OPG050;locus_tag=NBT03_gp030;product=CPXV053 protein;protein_id=YP_010377033.1 +NC_063383.1 RefSeq gene 33425 33649 . - . ID=gene-NBT03_gp031;Dbxref=GeneID:72551447;Name=OPG051;gbkey=Gene;gene=OPG051;gene_biotype=protein_coding;locus_tag=NBT03_gp031;old_locus_tag=MPXV-M5312_HM12_Rivers-035 +NC_063383.1 RefSeq CDS 33425 33649 . - 0 ID=cds-YP_010377034.1;Parent=gene-NBT03_gp031;Dbxref=GenBank:YP_010377034.1,GeneID:72551447;Name=OPG051;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp039%3B Hypothetical protein%3B similar to VACV-WR C13L and VACV-Cop F7L;gbkey=CDS;gene=OPG051;locus_tag=NBT03_gp031;product=CPXV054 protein;protein_id=YP_010377034.1 +NC_063383.1 RefSeq gene 33801 33995 . - . ID=gene-NBT03_gp032;Dbxref=GeneID:72551448;Name=OPG052;gbkey=Gene;gene=OPG052;gene_biotype=protein_coding;locus_tag=NBT03_gp032;old_locus_tag=MPXV-M5312_HM12_Rivers-036 +NC_063383.1 RefSeq CDS 33801 33995 . - 0 ID=cds-YP_010377035.1;Parent=gene-NBT03_gp032;Dbxref=GenBank:YP_010377035.1,GeneID:72551448;Name=OPG052;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp040%3B Cytoplasmic protein%3B similar to VACV-WR C14L and VACV-Cop F8L;gbkey=CDS;gene=OPG052;locus_tag=NBT03_gp032;product=Cytoplasmic protein;protein_id=YP_010377035.1 +NC_063383.1 RefSeq gene 34052 34690 . - . ID=gene-NBT03_gp033;Dbxref=GeneID:72551449;Name=OPG053;gbkey=Gene;gene=OPG053;gene_biotype=protein_coding;locus_tag=NBT03_gp033;old_locus_tag=MPXV-M5312_HM12_Rivers-037 +NC_063383.1 RefSeq CDS 34052 34690 . - 0 ID=cds-YP_010377036.1;Parent=gene-NBT03_gp033;Dbxref=GenBank:YP_010377036.1,GeneID:72551449;Name=OPG053;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp041%3B S-S bond formation pathway protein substrate%3B similar to VACV-WR C15L and VACV-Cop F9L;gbkey=CDS;gene=OPG053;locus_tag=NBT03_gp033;product=IMV membrane protein L1R;protein_id=YP_010377036.1 +NC_063383.1 RefSeq gene 34677 35996 . - . ID=gene-NBT03_gp034;Dbxref=GeneID:72551450;Name=OPG054;gbkey=Gene;gene=OPG054;gene_biotype=protein_coding;locus_tag=NBT03_gp034;old_locus_tag=MPXV-M5312_HM12_Rivers-038 +NC_063383.1 RefSeq CDS 34677 35996 . - 0 ID=cds-YP_010377037.1;Parent=gene-NBT03_gp034;Dbxref=GenBank:YP_010377037.1,GeneID:72551450;Name=OPG054;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp042%3B serine%3B Essential Ser/Thr kinase morph%3B similar to VACV-WR C16L and VACV-Cop F10L;gbkey=CDS;gene=OPG054;locus_tag=NBT03_gp034;product=Serine/threonine-protein kinase;protein_id=YP_010377037.1 +NC_063383.1 RefSeq gene 36019 37083 . - . ID=gene-NBT03_gp035;Dbxref=GeneID:72551451;Name=OPG055;gbkey=Gene;gene=OPG055;gene_biotype=protein_coding;locus_tag=NBT03_gp035;old_locus_tag=MPXV-M5312_HM12_Rivers-039 +NC_063383.1 RefSeq CDS 36019 37083 . - 0 ID=cds-YP_010377038.1;Parent=gene-NBT03_gp035;Dbxref=GenBank:YP_010377038.1,GeneID:72551451;Name=OPG055;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp043%3B RhoA signalling inhibitor%2C virus release protein%3B MC018%3B similar to VACV-WR C17L and VACV-Cop F11L;gbkey=CDS;gene=OPG055;locus_tag=NBT03_gp035;product=Protein F11;protein_id=YP_010377038.1 +NC_063383.1 RefSeq gene 37127 39034 . - . ID=gene-NBT03_gp036;Dbxref=GeneID:72551452;Name=OPG056;gbkey=Gene;gene=OPG056;gene_biotype=protein_coding;locus_tag=NBT03_gp036;old_locus_tag=MPXV-M5312_HM12_Rivers-040 +NC_063383.1 RefSeq CDS 37127 39034 . - 0 ID=cds-YP_010377039.1;Parent=gene-NBT03_gp036;Dbxref=GenBank:YP_010377039.1,GeneID:72551452;Name=OPG056;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp044%3B actin tail formation%3B EEV maturation protein%3B similar to VACV-WR C18L and VACV-Cop F12L;gbkey=CDS;gene=OPG056;locus_tag=NBT03_gp036;product=EEV maturation protein;protein_id=YP_010377039.1 +NC_063383.1 RefSeq gene 39077 40195 . - . ID=gene-NBT03_gp037;Dbxref=GeneID:72551453;Name=OPG057;gbkey=Gene;gene=OPG057;gene_biotype=protein_coding;locus_tag=NBT03_gp037;old_locus_tag=MPXV-M5312_HM12_Rivers-041 +NC_063383.1 RefSeq CDS 39077 40195 . - 0 ID=cds-YP_010377040.1;Parent=gene-NBT03_gp037;Dbxref=GenBank:YP_010377040.1,GeneID:72551453;Name=OPG057;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp045%3B major envelope antigen of EEV%3B wrapping of IMV to form IEV%3B phospholipase D-like%3B Palmitylated EEV membrane glycoprotein%3B similar to VACV-WR C19L and VACV-Cop F13L;gbkey=CDS;gene=OPG057;locus_tag=NBT03_gp037;product=Palmytilated EEV membrane protein;protein_id=YP_010377040.1 +NC_063383.1 RefSeq gene 40213 40434 . - . ID=gene-NBT03_gp038;Dbxref=GeneID:72551454;Name=OPG058;gbkey=Gene;gene=OPG058;gene_biotype=protein_coding;locus_tag=NBT03_gp038;old_locus_tag=MPXV-M5312_HM12_Rivers-042 +NC_063383.1 RefSeq CDS 40213 40434 . - 0 ID=cds-YP_010377041.1;Parent=gene-NBT03_gp038;Dbxref=GenBank:YP_010377041.1,GeneID:72551454;Name=OPG058;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp046%3B similar to VACV-WR C20L and VACV-Cop F14L;gbkey=CDS;gene=OPG058;locus_tag=NBT03_gp038;product=Protein F14 (1);protein_id=YP_010377041.1 +NC_063383.1 RefSeq gene 40484 40633 . - . ID=gene-NBT03_gp039;Dbxref=GeneID:72551455;Name=OPG059;gbkey=Gene;gene=OPG059;gene_biotype=protein_coding;locus_tag=NBT03_gp039;old_locus_tag=MPXV-M5312_HM12_Rivers-043 +NC_063383.1 RefSeq CDS 40484 40633 . - 0 ID=cds-YP_010377042.1;Parent=gene-NBT03_gp039;Dbxref=GenBank:YP_010377042.1,GeneID:72551455;Name=OPG059;Note=Taxonomic breadth: poxvirinae%3B IMV protein%3B C20.5L%3B similar to VACV-CopF14.5L;gbkey=CDS;gene=OPG059;locus_tag=NBT03_gp039;product=Cytochrome C oxidase;protein_id=YP_010377042.1 +NC_063383.1 RefSeq gene 40706 41182 . - . ID=gene-NBT03_gp040;Dbxref=GeneID:72551456;Name=OPG060;gbkey=Gene;gene=OPG060;gene_biotype=protein_coding;locus_tag=NBT03_gp040;old_locus_tag=MPXV-M5312_HM12_Rivers-044 +NC_063383.1 RefSeq CDS 40706 41182 . - 0 ID=cds-YP_010377043.1;Parent=gene-NBT03_gp040;Dbxref=GenBank:YP_010377043.1,GeneID:72551456;Name=OPG060;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp047%3B Unknown conserved protein%3B similar to VACV-WR C21L and VACV-Cop F15L;gbkey=CDS;gene=OPG060;locus_tag=NBT03_gp040;product=Protein F15;protein_id=YP_010377043.1 +NC_063383.1 RefSeq gene 41189 41884 . - . ID=gene-NBT03_gp041;Dbxref=GeneID:72551457;Name=OPG061;gbkey=Gene;gene=OPG061;gene_biotype=protein_coding;locus_tag=NBT03_gp041;old_locus_tag=MPXV-M5312_HM12_Rivers-045 +NC_063383.1 RefSeq CDS 41189 41884 . - 0 ID=cds-YP_010377044.1;Parent=gene-NBT03_gp041;Dbxref=GenBank:YP_010377044.1,GeneID:72551457;Name=OPG061;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp048%3B Non-functional Serine Recombinase%3B similar to VACV-WR C22L and VACV-Cop F16L;gbkey=CDS;gene=OPG061;locus_tag=NBT03_gp041;product=Protein F16 (1);protein_id=YP_010377044.1 +NC_063383.1 RefSeq gene 41947 42252 . + . ID=gene-NBT03_gp042;Dbxref=GeneID:72551458;Name=OPG062;gbkey=Gene;gene=OPG062;gene_biotype=protein_coding;locus_tag=NBT03_gp042;old_locus_tag=MPXV-M5312_HM12_Rivers-046 +NC_063383.1 RefSeq CDS 41947 42252 . + 0 ID=cds-YP_010377045.1;Parent=gene-NBT03_gp042;Dbxref=GenBank:YP_010377045.1,GeneID:72551458;Name=OPG062;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp049%3B virion core DNA-binding phosphoprotein (VP11)%3B mTOR antagonist%3B similar to VACV-WR C23R and VACV-Cop F17R;gbkey=CDS;gene=OPG062;locus_tag=NBT03_gp042;product=DNA-binding phosphoprotein (1);protein_id=YP_010377045.1 +NC_063383.1 RefSeq gene 42249 43688 . - . ID=gene-NBT03_gp043;Dbxref=GeneID:72551459;Name=OPG063;gbkey=Gene;gene=OPG063;gene_biotype=protein_coding;locus_tag=NBT03_gp043;old_locus_tag=MPXV-M5312_HM12_Rivers-047 +NC_063383.1 RefSeq CDS 42249 43688 . - 0 ID=cds-YP_010377046.1;Parent=gene-NBT03_gp043;Dbxref=GenBank:YP_010377046.1,GeneID:72551459;Name=OPG063;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp050%3B poly-A polymerase%2C Poly (A) polymerase catalytic subunit (VP55)%3B similar to VACV-WR F1L and VACV-Cop E1L;gbkey=CDS;gene=OPG063;locus_tag=NBT03_gp043;product=Poly(A) polymerase catalytic subunit (3);protein_id=YP_010377046.1 +NC_063383.1 RefSeq gene 43685 45898 . - . ID=gene-NBT03_gp044;Dbxref=GeneID:72551460;Name=OPG064;gbkey=Gene;gene=OPG064;gene_biotype=protein_coding;locus_tag=NBT03_gp044;old_locus_tag=MPXV-M5312_HM12_Rivers-048 +NC_063383.1 RefSeq CDS 43685 45898 . - 0 ID=cds-YP_010377047.1;Parent=gene-NBT03_gp044;Dbxref=GenBank:YP_010377047.1,GeneID:72551460;Name=OPG064;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp051%3B IEV morphogenesis%3B similar to VACV-WR F2L and VACV-Cop E2L;gbkey=CDS;gene=OPG064;locus_tag=NBT03_gp044;product=Iev morphogenesis protein;protein_id=YP_010377047.1 +NC_063383.1 RefSeq gene 46022 46483 . - . ID=gene-NBT03_gp045;Dbxref=GeneID:72551461;Name=OPG065;gbkey=Gene;gene=OPG065;gene_biotype=protein_coding;locus_tag=NBT03_gp045;old_locus_tag=MPXV-M5312_HM12_Rivers-049 +NC_063383.1 RefSeq CDS 46022 46483 . - 0 ID=cds-YP_010377048.1;Parent=gene-NBT03_gp045;Dbxref=GenBank:YP_010377048.1,GeneID:72551461;Name=OPG065;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp052%3B interferon resistance factor%3B two forms (25 kDa and 19 kDa) of the dsRNA-binding protein%3B inhibition of dsRNA-dependent protein kinase and 2-5A-synthet%3B dsRNA-binding protein%2C IFN resistance/PKR inhibitor (Z-DNA binding)%3B start of ORF is missing approx. 37 AA compared to CPXVs%3B similar to VACV-WR F3L and VACV-Cop E3L;gbkey=CDS;gene=OPG065;locus_tag=NBT03_gp045;product=Double-stranded RNA binding protein;protein_id=YP_010377048.1 +NC_063383.1 RefSeq gene 46649 47428 . - . ID=gene-NBT03_gp046;Dbxref=GeneID:72551462;Name=OPG066;gbkey=Gene;gene=OPG066;gene_biotype=protein_coding;locus_tag=NBT03_gp046;old_locus_tag=MPXV-M5312_HM12_Rivers-050 +NC_063383.1 RefSeq CDS 46649 47428 . - 0 ID=cds-YP_010377049.1;Parent=gene-NBT03_gp046;Dbxref=GenBank:YP_010377049.1,GeneID:72551462;Name=OPG066;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp053%3B RNA polymerase 30 kDa subunit (RPO30)%3B simultaneously intermediate stage promoter-specific transcription factor%2C VITF-1%3B similar to VACV-WR F4L and VACV-Cop E4L;gbkey=CDS;gene=OPG066;locus_tag=NBT03_gp046;product=DNA-directed RNA polymerase 30 kDa polypeptide;protein_id=YP_010377049.1 +NC_063383.1 RefSeq sequence_feature 47525 48062 . + . ID=id-NC_063383.1:47525..48062;exon_number=OPG067;gbkey=misc_feature;number=OPG067 +NC_063383.1 RefSeq gene 48201 49904 . + . ID=gene-NBT03_gp047;Dbxref=GeneID:72551463;Name=OPG068;gbkey=Gene;gene=OPG068;gene_biotype=protein_coding;locus_tag=NBT03_gp047;old_locus_tag=MPXV-M5312_HM12_Rivers-052 +NC_063383.1 RefSeq CDS 48201 49904 . + 0 ID=cds-YP_010377051.1;Parent=gene-NBT03_gp047;Dbxref=GenBank:YP_010377051.1,GeneID:72551463;Name=OPG068;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp054%3B Virion protein%3B similar to VACV-WR F5R and VACV-Cop E6R;gbkey=CDS;gene=OPG068;locus_tag=NBT03_gp047;product=IMV membrane protein E6;protein_id=YP_010377051.1 +NC_063383.1 RefSeq gene 49986 50486 . + . ID=gene-NBT03_gp048;Dbxref=GeneID:72551464;Name=OPG069;gbkey=Gene;gene=OPG069;gene_biotype=protein_coding;locus_tag=NBT03_gp048;old_locus_tag=MPXV-M5312_HM12_Rivers-053 +NC_063383.1 RefSeq CDS 49986 50486 . + 0 ID=cds-YP_010377052.1;Parent=gene-NBT03_gp048;Dbxref=GenBank:YP_010377052.1,GeneID:72551464;Name=OPG069;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp055%3B soluble myristylated protein%3B similar to VACV-WR F6R and VACV-Cop E7R;gbkey=CDS;gene=OPG069;locus_tag=NBT03_gp048;product=Myristoylated protein E7;protein_id=YP_010377052.1 +NC_063383.1 RefSeq gene 50590 51411 . + . ID=gene-NBT03_gp049;Dbxref=GeneID:72551465;Name=OPG070;gbkey=Gene;gene=OPG070;gene_biotype=protein_coding;locus_tag=NBT03_gp049;old_locus_tag=MPXV-M5312_HM12_Rivers-054 +NC_063383.1 RefSeq CDS 50590 51411 . + 0 ID=cds-YP_010377053.1;Parent=gene-NBT03_gp049;Dbxref=GenBank:YP_010377053.1,GeneID:72551465;Name=OPG070;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp056%3B ER-localized membrane protein%2C virion core protein%3B similar to VACV-WR F7R and VACV-Cop E8R;gbkey=CDS;gene=OPG070;locus_tag=NBT03_gp049;product=Membrane protein E8;protein_id=YP_010377053.1 +NC_063383.1 RefSeq gene 51418 54438 . - . ID=gene-NBT03_gp050;Dbxref=GeneID:72551466;Name=OPG071;gbkey=Gene;gene=OPG071;gene_biotype=protein_coding;locus_tag=NBT03_gp050;old_locus_tag=MPXV-M5312_HM12_Rivers-055 +NC_063383.1 RefSeq CDS 51418 54438 . - 0 ID=cds-YP_010377054.1;Parent=gene-NBT03_gp050;Dbxref=GenBank:YP_010377054.1,GeneID:72551466;Name=OPG071;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp057%3B DNA polymerase%2C catalytic subunit%3B similar to VACV-WR F8L and VACV-Cop E9L;gbkey=CDS;gene=OPG071;locus_tag=NBT03_gp050;product=DNA polymerase (2);protein_id=YP_010377054.1 +NC_063383.1 RefSeq gene 54470 54757 . + . ID=gene-NBT03_gp051;Dbxref=GeneID:72551467;Name=OPG072;gbkey=Gene;gene=OPG072;gene_biotype=protein_coding;locus_tag=NBT03_gp051;old_locus_tag=MPXV-M5312_HM12_Rivers-056 +NC_063383.1 RefSeq CDS 54470 54757 . + 0 ID=cds-YP_010377055.1;Parent=gene-NBT03_gp051;Dbxref=GenBank:YP_010377055.1,GeneID:72551467;Name=OPG072;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp058%3B protein disulfide bond-forming enzyme%3B Sulfhydryl oxidase (FAD-linked)%3B similar to VACV-WR F9R and VACV-Cop E10R;gbkey=CDS;gene=OPG072;locus_tag=NBT03_gp051;product=Sulfhydryl oxidase;protein_id=YP_010377055.1 +NC_063383.1 RefSeq gene 54752 55141 . - . ID=gene-NBT03_gp052;Dbxref=GeneID:72551468;Name=OPG073;gbkey=Gene;gene=OPG073;gene_biotype=protein_coding;locus_tag=NBT03_gp052;old_locus_tag=MPXV-M5312_HM12_Rivers-057 +NC_063383.1 RefSeq CDS 54752 55141 . - 0 ID=cds-YP_010377056.1;Parent=gene-NBT03_gp052;Dbxref=GenBank:YP_010377056.1,GeneID:72551468;Name=OPG073;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp059%3B virion core protein%3B similar to VACV-WR F10L and VACV-Cop E11L;gbkey=CDS;gene=OPG073;locus_tag=NBT03_gp052;product=Virion core protein E11;protein_id=YP_010377056.1 +NC_063383.1 RefSeq gene 55128 57125 . - . ID=gene-NBT03_gp053;Dbxref=GeneID:72551469;Name=OPG074;gbkey=Gene;gene=OPG074;gene_biotype=protein_coding;locus_tag=NBT03_gp053;old_locus_tag=MPXV-M5312_HM12_Rivers-058 +NC_063383.1 RefSeq CDS 55128 57125 . - 0 ID=cds-YP_010377057.1;Parent=gene-NBT03_gp053;Dbxref=GenBank:YP_010377057.1,GeneID:72551469;Name=OPG074;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp060%3B Membrane protein%3B similar to VACV-WR Q1L and VACV-Cop O1L;gbkey=CDS;gene=OPG074;locus_tag=NBT03_gp053;product=Iev morphogenesis protein;protein_id=YP_010377057.1 +NC_063383.1 RefSeq gene 57172 57498 . - . ID=gene-NBT03_gp054;Dbxref=GeneID:72551470;Name=OPG075;gbkey=Gene;gene=OPG075;gene_biotype=protein_coding;locus_tag=NBT03_gp054;old_locus_tag=MPXV-M5312_HM12_Rivers-059 +NC_063383.1 RefSeq CDS 57172 57498 . - 0 ID=cds-YP_010377058.1;Parent=gene-NBT03_gp054;Dbxref=GenBank:YP_010377058.1,GeneID:72551470;Name=OPG075;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp061%3B virion-associated glutaredoxin%3B glutaredoxin 1%3B similar to VACV-WR Q2L and VACV-Cop O2L;gbkey=CDS;gene=OPG075;locus_tag=NBT03_gp054;product=Glutaredoxin-1;protein_id=YP_010377058.1 +NC_063383.1 RefSeq gene 57523 57630 . - . ID=gene-NBT03_gp055;Dbxref=GeneID:72551471;Name=OPG076;gbkey=Gene;gene=OPG076;gene_biotype=protein_coding;locus_tag=NBT03_gp055 +NC_063383.1 RefSeq CDS 57523 57630 . - 0 ID=cds-YP_010377183.1;Parent=gene-NBT03_gp055;Dbxref=GenBank:YP_010377183.1,GeneID:72551471;Name=OPG076;gbkey=CDS;gene=OPG076;locus_tag=NBT03_gp055;product=MV membrane EFC component;protein_id=YP_010377183.1 +NC_063383.1 RefSeq gene 57645 58583 . - . ID=gene-NBT03_gp056;Dbxref=GeneID:72551472;Name=OPG077;gbkey=Gene;gene=OPG077;gene_biotype=protein_coding;locus_tag=NBT03_gp056;old_locus_tag=MPXV-M5312_HM12_Rivers-060 +NC_063383.1 RefSeq CDS 57645 58583 . - 0 ID=cds-YP_010377059.1;Parent=gene-NBT03_gp056;Dbxref=GenBank:YP_010377059.1,GeneID:72551472;Name=OPG077;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp062%3B virosomal protein essential for virus multiplication%3B DNA-binding core protein%3B similar to VACV-WR I1L and VACV-Cop I1L;gbkey=CDS;gene=OPG077;locus_tag=NBT03_gp056;product=Telomere-binding protein I1;protein_id=YP_010377059.1 +NC_063383.1 RefSeq gene 58590 58811 . - . ID=gene-NBT03_gp057;Dbxref=GeneID:72551473;Name=OPG078;gbkey=Gene;gene=OPG078;gene_biotype=protein_coding;locus_tag=NBT03_gp057;old_locus_tag=MPXV-M5312_HM12_Rivers-061 +NC_063383.1 RefSeq CDS 58590 58811 . - 0 ID=cds-YP_010377060.1;Parent=gene-NBT03_gp057;Dbxref=GenBank:YP_010377060.1,GeneID:72551473;Name=OPG078;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp063%3B IMV membrane protein%3B similar to VACV-WR I2L and VACV-Cop I2L;gbkey=CDS;gene=OPG078;locus_tag=NBT03_gp057;product=IMV membrane protein I2;protein_id=YP_010377060.1 +NC_063383.1 RefSeq gene 58812 59621 . - . ID=gene-NBT03_gp058;Dbxref=GeneID:72551474;Name=OPG079;gbkey=Gene;gene=OPG079;gene_biotype=protein_coding;locus_tag=NBT03_gp058;old_locus_tag=MPXV-M5312_HM12_Rivers-062 +NC_063383.1 RefSeq CDS 58812 59621 . - 0 ID=cds-YP_010377061.1;Parent=gene-NBT03_gp058;Dbxref=GenBank:YP_010377061.1,GeneID:72551474;Name=OPG079;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp064%3B virosomal ssDNA-binding phosphoprotein%3B interacts with R2 subunit of ribonucleotide reductase%3B similar to VACV-WR I3L and VACV-Cop I3L;gbkey=CDS;gene=OPG079;locus_tag=NBT03_gp058;product=DNA-binding phosphoprotein (2);protein_id=YP_010377061.1 +NC_063383.1 RefSeq gene 59703 62018 . - . ID=gene-NBT03_gp059;Dbxref=GeneID:72551475;Name=OPG080;gbkey=Gene;gene=OPG080;gene_biotype=protein_coding;locus_tag=NBT03_gp059;old_locus_tag=MPXV-M5312_HM12_Rivers-063 +NC_063383.1 RefSeq CDS 59703 62018 . - 0 ID=cds-YP_010377062.1;Parent=gene-NBT03_gp059;Dbxref=GenBank:YP_010377062.1,GeneID:72551475;Name=OPG080;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp065%3B ribonucleotide reductase%2C large subunit%2C R1%3B similar to VACV-WR I4L and VACV-Cop I4L;gbkey=CDS;gene=OPG080;locus_tag=NBT03_gp059;product=Ribonucleoside-diphosphate reductase (2);protein_id=YP_010377062.1 +NC_063383.1 RefSeq gene 62046 62285 . - . ID=gene-NBT03_gp060;Dbxref=GeneID:72551476;Name=OPG081;gbkey=Gene;gene=OPG081;gene_biotype=protein_coding;locus_tag=NBT03_gp060;old_locus_tag=MPXV-M5312_HM12_Rivers-064 +NC_063383.1 RefSeq CDS 62046 62285 . - 0 ID=cds-YP_010377063.1;Parent=gene-NBT03_gp060;Dbxref=GenBank:YP_010377063.1,GeneID:72551476;Name=OPG081;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp066%3B IMV surface membrane protein%2C VP13%3B similar to VACV-WR I5L and VACV-Cop I5L;gbkey=CDS;gene=OPG081;locus_tag=NBT03_gp060;product=IMV membrane protein I5;protein_id=YP_010377063.1 +NC_063383.1 RefSeq gene 62304 63452 . - . ID=gene-NBT03_gp061;Dbxref=GeneID:72551477;Name=OPG082;gbkey=Gene;gene=OPG082;gene_biotype=protein_coding;locus_tag=NBT03_gp061;old_locus_tag=MPXV-M5312_HM12_Rivers-065 +NC_063383.1 RefSeq CDS 62304 63452 . - 0 ID=cds-YP_010377064.1;Parent=gene-NBT03_gp061;Dbxref=GenBank:YP_010377064.1,GeneID:72551477;Name=OPG082;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp067%3B Telomere-binding protein%3B similar to VACV-WR I6L and VACV-Cop I6L;gbkey=CDS;gene=OPG082;locus_tag=NBT03_gp061;product=Telomere-binding protein;protein_id=YP_010377064.1 +NC_063383.1 RefSeq gene 63445 64716 . - . ID=gene-NBT03_gp062;Dbxref=GeneID:72551478;Name=OPG083;gbkey=Gene;gene=OPG083;gene_biotype=protein_coding;locus_tag=NBT03_gp062;old_locus_tag=MPXV-M5312_HM12_Rivers-066 +NC_063383.1 RefSeq CDS 63445 64716 . - 0 ID=cds-YP_010377065.1;Parent=gene-NBT03_gp062;Dbxref=GenBank:YP_010377065.1,GeneID:72551478;Name=OPG083;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp068%3B virion core protein%3B similar to DNA topoisomerase II%3B Virion core cysteine protease%3B similar to VACV-WR I7L and VACV-Cop I7L;gbkey=CDS;gene=OPG083;locus_tag=NBT03_gp062;product=Viral core cysteine proteinase;protein_id=YP_010377065.1 +NC_063383.1 RefSeq gene 64722 66752 . + . ID=gene-NBT03_gp063;Dbxref=GeneID:72551479;Name=OPG084;gbkey=Gene;gene=OPG084;gene_biotype=protein_coding;locus_tag=NBT03_gp063;old_locus_tag=MPXV-M5312_HM12_Rivers-067 +NC_063383.1 RefSeq CDS 64722 66752 . + 0 ID=cds-YP_010377066.1;Parent=gene-NBT03_gp063;Dbxref=GenBank:YP_010377066.1,GeneID:72551479;Name=OPG084;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp069%3B nucleoside triphosphate phosphohydrolase II%2C NPH-II%3B DNA and RNA helicase%3B DExH-NPH-II domain%3B similar to VACV-WR I8R and VACV-Cop I8R;gbkey=CDS;gene=OPG084;locus_tag=NBT03_gp063;product=RNA helicase NPH-II (2);protein_id=YP_010377066.1 +NC_063383.1 RefSeq gene 66756 68531 . - . ID=gene-NBT03_gp064;Dbxref=GeneID:72551480;Name=OPG085;gbkey=Gene;gene=OPG085;gene_biotype=protein_coding;locus_tag=NBT03_gp064;old_locus_tag=MPXV-M5312_HM12_Rivers-068 +NC_063383.1 RefSeq CDS 66756 68531 . - 0 ID=cds-YP_010377067.1;Parent=gene-NBT03_gp064;Dbxref=GenBank:YP_010377067.1,GeneID:72551480;Name=OPG085;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp070%3B proteinase%3B Metalloprotease%3B similar to VACV-WR G1L and VACV-Cop G1L;gbkey=CDS;gene=OPG085;locus_tag=NBT03_gp064;product=Metalloendopeptidase;protein_id=YP_010377067.1 +NC_063383.1 RefSeq gene 68528 68863 . - . ID=gene-NBT03_gp065;Dbxref=GeneID:72551481;Name=OPG086;gbkey=Gene;gene=OPG086;gene_biotype=protein_coding;locus_tag=NBT03_gp065;old_locus_tag=MPXV-M5312_HM12_Rivers-069 +NC_063383.1 RefSeq CDS 68528 68863 . - 0 ID=cds-YP_010377068.1;Parent=gene-NBT03_gp065;Dbxref=GenBank:YP_010377068.1,GeneID:72551481;Name=OPG086;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp071%3B Entry/fusion complex component%3B similar to VACV-WR G2L and VACV-Cop G3L;gbkey=CDS;gene=OPG086;locus_tag=NBT03_gp065;product=Entry/fusion complex component;protein_id=YP_010377068.1 +NC_063383.1 RefSeq gene 68857 69519 . + . ID=gene-NBT03_gp066;Dbxref=GeneID:72551482;Name=OPG087;gbkey=Gene;gene=OPG087;gene_biotype=protein_coding;locus_tag=NBT03_gp066;old_locus_tag=MPXV-M5312_HM12_Rivers-070 +NC_063383.1 RefSeq CDS 68857 69519 . + 0 ID=cds-YP_010377069.1;Parent=gene-NBT03_gp066;Dbxref=GenBank:YP_010377069.1,GeneID:72551482;Name=OPG087;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp072%3B VLTF (late transcription elongation factor)%3B similar to VACV-WR G3R and VACV-Cop G2R;gbkey=CDS;gene=OPG087;locus_tag=NBT03_gp066;product=Late transcription elongation factor;protein_id=YP_010377069.1 +NC_063383.1 RefSeq gene 69489 69863 . - . ID=gene-NBT03_gp067;Dbxref=GeneID:72551483;Name=OPG088;gbkey=Gene;gene=OPG088;gene_biotype=protein_coding;locus_tag=NBT03_gp067;old_locus_tag=MPXV-M5312_HM12_Rivers-071 +NC_063383.1 RefSeq CDS 69489 69863 . - 0 ID=cds-YP_010377070.1;Parent=gene-NBT03_gp067;Dbxref=GenBank:YP_010377070.1,GeneID:72551483;Name=OPG088;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp073%3B virion-associated glutaredoxin%3B Glutaredoxin-like protein%3B similar to VACV-WR G4L and VACV-Cop G4L;gbkey=CDS;gene=OPG088;locus_tag=NBT03_gp067;product=Glutaredoxin-2;protein_id=YP_010377070.1 +NC_063383.1 RefSeq gene 69866 71170 . + . ID=gene-NBT03_gp068;Dbxref=GeneID:72551484;Name=OPG089;gbkey=Gene;gene=OPG089;gene_biotype=protein_coding;locus_tag=NBT03_gp068;old_locus_tag=MPXV-M5312_HM12_Rivers-072 +NC_063383.1 RefSeq CDS 69866 71170 . + 0 ID=cds-YP_010377071.1;Parent=gene-NBT03_gp068;Dbxref=GenBank:YP_010377071.1,GeneID:72551484;Name=OPG089;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp074%3B FEN1-like nuclease%3B similar to VACV-WR G5R and VACV-Cop G5R;gbkey=CDS;gene=OPG089;locus_tag=NBT03_gp068;product=FEN1-like nuclease;protein_id=YP_010377071.1 +NC_063383.1 RefSeq gene 71179 71370 . + . ID=gene-NBT03_gp069;Dbxref=GeneID:72551485;Name=OPG090;gbkey=Gene;gene=OPG090;gene_biotype=protein_coding;locus_tag=NBT03_gp069;old_locus_tag=MPXV-M5312_HM12_Rivers-073 +NC_063383.1 RefSeq CDS 71179 71370 . + 0 ID=cds-YP_010377072.1;Parent=gene-NBT03_gp069;Dbxref=GenBank:YP_010377072.1,GeneID:72551485;Name=OPG090;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp075%3B RNA polymerase subunit%2C 7 kDa subunit (RPO7)%3B similar to VACV-WR G6R and VACV-Cop G5.5R;gbkey=CDS;gene=OPG090;locus_tag=NBT03_gp069;product=DNA-directed RNA polymerase 7 kDa subunit;protein_id=YP_010377072.1 +NC_063383.1 RefSeq gene 71370 71867 . + . ID=gene-NBT03_gp070;Dbxref=GeneID:72551486;Name=OPG091;gbkey=Gene;gene=OPG091;gene_biotype=protein_coding;locus_tag=NBT03_gp070;old_locus_tag=MPXV-M5312_HM12_Rivers-074 +NC_063383.1 RefSeq CDS 71370 71867 . + 0 ID=cds-YP_010377073.1;Parent=gene-NBT03_gp070;Dbxref=GenBank:YP_010377073.1,GeneID:72551486;Name=OPG091;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp076%3B NLPc/P60 superfamily protein%3B similar to VACV-WR G7R and VACV-Cop G6R;gbkey=CDS;gene=OPG091;locus_tag=NBT03_gp070;product=Nlpc/p60 superfamily protein;protein_id=YP_010377073.1 +NC_063383.1 RefSeq gene 71832 72947 . - . ID=gene-NBT03_gp071;Dbxref=GeneID:72551487;Name=OPG092;gbkey=Gene;gene=OPG092;gene_biotype=protein_coding;locus_tag=NBT03_gp071;old_locus_tag=MPXV-M5312_HM12_Rivers-075 +NC_063383.1 RefSeq CDS 71832 72947 . - 0 ID=cds-YP_010377074.1;Parent=gene-NBT03_gp071;Dbxref=GenBank:YP_010377074.1,GeneID:72551487;Name=OPG092;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp077%3B virion protein%3B Virion phosphoprotein%2C early morphogenesis%3B similar to VACV-WR G8L and VACV-Cop G7L;gbkey=CDS;gene=OPG092;locus_tag=NBT03_gp071;product=Assembly protein G7;protein_id=YP_010377074.1 +NC_063383.1 RefSeq gene 72978 73760 . + . ID=gene-NBT03_gp072;Dbxref=GeneID:72551488;Name=OPG093;gbkey=Gene;gene=OPG093;gene_biotype=protein_coding;locus_tag=NBT03_gp072;old_locus_tag=MPXV-M5312_HM12_Rivers-076 +NC_063383.1 RefSeq CDS 72978 73760 . + 0 ID=cds-YP_010377075.1;Parent=gene-NBT03_gp072;Dbxref=GenBank:YP_010377075.1,GeneID:72551488;Name=OPG093;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp078%3B late gene transcription factor%2C VLTF-1%3B similar to VACV-WR G9R and VACV-Cop G8R;gbkey=CDS;gene=OPG093;locus_tag=NBT03_gp072;product=Late transcription factor VLTF-1;protein_id=YP_010377075.1 +NC_063383.1 RefSeq gene 73780 74802 . + . ID=gene-NBT03_gp073;Dbxref=GeneID:72551489;Name=OPG094;gbkey=Gene;gene=OPG094;gene_biotype=protein_coding;locus_tag=NBT03_gp073;old_locus_tag=MPXV-M5312_HM12_Rivers-077 +NC_063383.1 RefSeq CDS 73780 74802 . + 0 ID=cds-YP_010377076.1;Parent=gene-NBT03_gp073;Dbxref=GenBank:YP_010377076.1,GeneID:72551489;Name=OPG094;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp079%3B myristylated protein%3B Entry/fusion complex component%2C myristylprotein%3B similar to VACV-WR G10R and VACV-Cop G9R;gbkey=CDS;gene=OPG094;locus_tag=NBT03_gp073;product=Myristylated protein;protein_id=YP_010377076.1 +NC_063383.1 RefSeq gene 74803 75555 . + . ID=gene-NBT03_gp074;Dbxref=GeneID:72551490;Name=OPG095;gbkey=Gene;gene=OPG095;gene_biotype=protein_coding;locus_tag=NBT03_gp074;old_locus_tag=MPXV-M5312_HM12_Rivers-078 +NC_063383.1 RefSeq CDS 74803 75555 . + 0 ID=cds-YP_010377077.1;Parent=gene-NBT03_gp074;Dbxref=GenBank:YP_010377077.1,GeneID:72551490;Name=OPG095;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp080%3B myristylated IMV surface membrane protein%3B similar to VACV-WR M1R and VACV-Cop L1R;gbkey=CDS;gene=OPG095;locus_tag=NBT03_gp074;product=IMV membrane protein L1R;protein_id=YP_010377077.1 +NC_063383.1 RefSeq gene 75587 75865 . + . ID=gene-NBT03_gp075;Dbxref=GeneID:72551491;Name=OPG096;gbkey=Gene;gene=OPG096;gene_biotype=protein_coding;locus_tag=NBT03_gp075;old_locus_tag=MPXV-M5312_HM12_Rivers-079 +NC_063383.1 RefSeq CDS 75587 75865 . + 0 ID=cds-YP_010377078.1;Parent=gene-NBT03_gp075;Dbxref=GenBank:YP_010377078.1,GeneID:72551491;Name=OPG096;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp081%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR M2R and VACV-Cop L2R;gbkey=CDS;gene=OPG096;locus_tag=NBT03_gp075;product=Crescent membrane and immature virion formation protein;protein_id=YP_010377078.1 +NC_063383.1 RefSeq gene 75841 76875 . - . ID=gene-NBT03_gp076;Dbxref=GeneID:72551492;Name=OPG097;gbkey=Gene;gene=OPG097;gene_biotype=protein_coding;locus_tag=NBT03_gp076;old_locus_tag=MPXV-M5312_HM12_Rivers-080 +NC_063383.1 RefSeq CDS 75841 76875 . - 0 ID=cds-YP_010377079.1;Parent=gene-NBT03_gp076;Dbxref=GenBank:YP_010377079.1,GeneID:72551492;Name=OPG097;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp082%3B Internal virion protein%3B similar to VACV-WR M3L and VACV-Cop L3L;gbkey=CDS;gene=OPG097;locus_tag=NBT03_gp076;product=Internal virion L3/FP4 protein;protein_id=YP_010377079.1 +NC_063383.1 RefSeq gene 76900 77655 . + . ID=gene-NBT03_gp077;Dbxref=GeneID:72551493;Name=OPG098;gbkey=Gene;gene=OPG098;gene_biotype=protein_coding;locus_tag=NBT03_gp077;old_locus_tag=MPXV-M5312_HM12_Rivers-081 +NC_063383.1 RefSeq CDS 76900 77655 . + 0 ID=cds-YP_010377080.1;Parent=gene-NBT03_gp077;Dbxref=GenBank:YP_010377080.1,GeneID:72551493;Name=OPG098;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp083%3B virion core protein vp8%3B stimulation of I8R helicase activity%3B ss/dsDNA binding protein (VP8)%3B similar to VACV-WR M4R and VACV-Cop L4R;gbkey=CDS;gene=OPG098;locus_tag=NBT03_gp077;product=Nucleic acid binding protein VP8/L4R;protein_id=YP_010377080.1 +NC_063383.1 RefSeq gene 77665 78051 . + . ID=gene-NBT03_gp078;Dbxref=GeneID:72551494;Name=OPG099;gbkey=Gene;gene=OPG099;gene_biotype=protein_coding;locus_tag=NBT03_gp078;old_locus_tag=MPXV-M5312_HM12_Rivers-082 +NC_063383.1 RefSeq CDS 77665 78051 . + 0 ID=cds-YP_010377081.1;Parent=gene-NBT03_gp078;Dbxref=GenBank:YP_010377081.1,GeneID:72551494;Name=OPG099;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp084%3B Entry and Fusion IMV protein%3B similar to VACV-WR M5R and VACV-Cop L5R;gbkey=CDS;gene=OPG099;locus_tag=NBT03_gp078;product=Membrane protein CL5;protein_id=YP_010377081.1 +NC_063383.1 RefSeq gene 78008 78466 . + . ID=gene-NBT03_gp079;Dbxref=GeneID:72551495;Name=OPG100;gbkey=Gene;gene=OPG100;gene_biotype=protein_coding;locus_tag=NBT03_gp079;old_locus_tag=MPXV-M5312_HM12_Rivers-083 +NC_063383.1 RefSeq CDS 78008 78466 . + 0 ID=cds-YP_010377082.1;Parent=gene-NBT03_gp079;Dbxref=GenBank:YP_010377082.1,GeneID:72551495;Name=OPG100;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp085%3B Virion morph%3B similar to VACV-WR L1R and VACV-Cop J1R;gbkey=CDS;gene=OPG100;locus_tag=NBT03_gp079;product=IMV membrane protein J1;protein_id=YP_010377082.1 +NC_063383.1 RefSeq gene 78486 79019 . + . ID=gene-NBT03_gp080;Dbxref=GeneID:72551496;Name=OPG101;gbkey=Gene;gene=OPG101;gene_biotype=protein_coding;locus_tag=NBT03_gp080;old_locus_tag=MPXV-M5312_HM12_Rivers-084 +NC_063383.1 RefSeq CDS 78486 79019 . + 0 ID=cds-YP_010377083.1;Parent=gene-NBT03_gp080;Dbxref=GenBank:YP_010377083.1,GeneID:72551496;Name=OPG101;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp086%3B thymidine kinase%3B similar to VACV-WR L2R and VACV-Cop J2R;gbkey=CDS;gene=OPG101;locus_tag=NBT03_gp080;product=Thymidine kinase;protein_id=YP_010377083.1 +NC_063383.1 RefSeq gene 79085 80086 . + . ID=gene-NBT03_gp081;Dbxref=GeneID:72551497;Name=OPG102;gbkey=Gene;gene=OPG102;gene_biotype=protein_coding;locus_tag=NBT03_gp081;old_locus_tag=MPXV-M5312_HM12_Rivers-085 +NC_063383.1 RefSeq CDS 79085 80086 . + 0 ID=cds-YP_010377084.1;Parent=gene-NBT03_gp081;Dbxref=GenBank:YP_010377084.1,GeneID:72551497;Name=OPG102;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp087%3B poly-A polymerase%2C stimulatory subunit%2C simultaneously cap-specific mRNA (nucleoside-O2'-)-methyltransferase%3B Poly (A) polymerase small subunit (VP39)%3B similar to VACV-WR L3R and VACV-Cop J3R;gbkey=CDS;gene=OPG102;locus_tag=NBT03_gp081;product=Cap-specific mRNA;protein_id=YP_010377084.1 +NC_063383.1 RefSeq gene 80001 80558 . + . ID=gene-NBT03_gp082;Dbxref=GeneID:72551498;Name=OPG103;gbkey=Gene;gene=OPG103;gene_biotype=protein_coding;locus_tag=NBT03_gp082;old_locus_tag=MPXV-M5312_HM12_Rivers-086 +NC_063383.1 RefSeq CDS 80001 80558 . + 0 ID=cds-YP_010377085.1;Parent=gene-NBT03_gp082;Dbxref=GenBank:YP_010377085.1,GeneID:72551498;Name=OPG103;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp088%3B RNA polymerase%2C 22 kDa subunit (RPO22)%3B similar to VACV-WR L4R and VACV-Cop J4R;gbkey=CDS;gene=OPG103;locus_tag=NBT03_gp082;product=DNA-directed RNA polymerase subunit;protein_id=YP_010377085.1 +NC_063383.1 RefSeq gene 80618 81019 . - . ID=gene-NBT03_gp083;Dbxref=GeneID:72551499;Name=OPG104;gbkey=Gene;gene=OPG104;gene_biotype=protein_coding;locus_tag=NBT03_gp083;old_locus_tag=MPXV-M5312_HM12_Rivers-087 +NC_063383.1 RefSeq CDS 80618 81019 . - 0 ID=cds-YP_010377086.1;Parent=gene-NBT03_gp083;Dbxref=GenBank:YP_010377086.1,GeneID:72551499;Name=OPG104;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp089%3B essential for virus multiplication%3B IMV membrane protein%3B similar to VACV-WR L5L and VACV-Cop J5L;gbkey=CDS;gene=OPG104;locus_tag=NBT03_gp083;product=Myristylated protein;protein_id=YP_010377086.1 +NC_063383.1 RefSeq gene 81126 84986 . + . ID=gene-NBT03_gp084;Dbxref=GeneID:72551500;Name=OPG105;gbkey=Gene;gene=OPG105;gene_biotype=protein_coding;locus_tag=NBT03_gp084;old_locus_tag=MPXV-M5312_HM12_Rivers-088 +NC_063383.1 RefSeq CDS 81126 84986 . + 0 ID=cds-YP_010377087.1;Parent=gene-NBT03_gp084;Dbxref=GenBank:YP_010377087.1,GeneID:72551500;Name=OPG105;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp090%3B RNA polymerase%2C 147 kDa subunit (RPO147)%3B similar to VACV-WR L6R and VACV-Cop J6R;gbkey=CDS;gene=OPG105;locus_tag=NBT03_gp084;product=DNA-dependent RNA polymerase subunit rpo147;protein_id=YP_010377087.1 +NC_063383.1 RefSeq gene 84983 85498 . - . ID=gene-NBT03_gp085;Dbxref=GeneID:72551501;Name=OPG106;gbkey=Gene;gene=OPG106;gene_biotype=protein_coding;locus_tag=NBT03_gp085;old_locus_tag=MPXV-M5312_HM12_Rivers-089 +NC_063383.1 RefSeq CDS 84983 85498 . - 0 ID=cds-YP_010377088.1;Parent=gene-NBT03_gp085;Dbxref=GenBank:YP_010377088.1,GeneID:72551501;Name=OPG106;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp091%3B tyrosine%3B Tyr/Ser phosphatase%2C IFN-gamma inhibitor%3B similar to VACV-WR H1L and VACV-Cop H1L;gbkey=CDS;gene=OPG106;locus_tag=NBT03_gp085;product=Tyr/ser protein phosphatase;protein_id=YP_010377088.1 +NC_063383.1 RefSeq gene 85512 86081 . + . ID=gene-NBT03_gp086;Dbxref=GeneID:72551502;Name=OPG107;gbkey=Gene;gene=OPG107;gene_biotype=protein_coding;locus_tag=NBT03_gp086;old_locus_tag=MPXV-M5312_HM12_Rivers-090 +NC_063383.1 RefSeq CDS 85512 86081 . + 0 ID=cds-YP_010377089.1;Parent=gene-NBT03_gp086;Dbxref=GenBank:YP_010377089.1,GeneID:72551502;Name=OPG107;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp092%3B IMV membrane protein%3B similar to VACV-WR H2R and VACV-Cop H2R;gbkey=CDS;gene=OPG107;locus_tag=NBT03_gp086;product=Entry-fusion complex essential component;protein_id=YP_010377089.1 +NC_063383.1 RefSeq gene 86085 87059 . - . ID=gene-NBT03_gp087;Dbxref=GeneID:72551503;Name=OPG108;gbkey=Gene;gene=OPG108;gene_biotype=protein_coding;locus_tag=NBT03_gp087;old_locus_tag=MPXV-M5312_HM12_Rivers-091 +NC_063383.1 RefSeq CDS 86085 87059 . - 0 ID=cds-YP_010377090.1;Parent=gene-NBT03_gp087;Dbxref=GenBank:YP_010377090.1,GeneID:72551503;Name=OPG108;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp093%3B IMV surface membrane protein%3B IMV heparin binding surface protein%3B similar to VACV-WR H3L and VACV-Cop H3L;gbkey=CDS;gene=OPG108;locus_tag=NBT03_gp087;product=IMV heparin binding surface protein;protein_id=YP_010377090.1 +NC_063383.1 RefSeq gene 87060 89447 . - . ID=gene-NBT03_gp088;Dbxref=GeneID:72551504;Name=OPG109;gbkey=Gene;gene=OPG109;gene_biotype=protein_coding;locus_tag=NBT03_gp088;old_locus_tag=MPXV-M5312_HM12_Rivers-092 +NC_063383.1 RefSeq CDS 87060 89447 . - 0 ID=cds-YP_010377091.1;Parent=gene-NBT03_gp088;Dbxref=GenBank:YP_010377091.1,GeneID:72551504;Name=OPG109;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp094%3B virion core RNA polymerase-associated protein%2C RAP94%3B similar to VACV-WR H4L and VACV-Cop H4L;gbkey=CDS;gene=OPG109;locus_tag=NBT03_gp088;product=RNA polymerase-associated transcription-specificity factor RAP94;protein_id=YP_010377091.1 +NC_063383.1 RefSeq gene 89632 90264 . + . ID=gene-NBT03_gp089;Dbxref=GeneID:72551505;Name=OPG110;gbkey=Gene;gene=OPG110;gene_biotype=protein_coding;locus_tag=NBT03_gp089;old_locus_tag=MPXV-M5312_HM12_Rivers-093 +NC_063383.1 RefSeq CDS 89632 90264 . + 0 ID=cds-YP_010377092.1;Parent=gene-NBT03_gp089;Dbxref=GenBank:YP_010377092.1,GeneID:72551505;Name=OPG110;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp095%3B virosome-associated late gene transcription factor%2C VLTF-4%3B Ca2+-binding motif%3B similar to VACV-WR H5R and VACV-Cop H5R;gbkey=CDS;gene=OPG110;locus_tag=NBT03_gp089;product=Late transcription factor VLTF-4 (1);protein_id=YP_010377092.1 +NC_063383.1 RefSeq gene 90265 91209 . + . ID=gene-NBT03_gp090;Dbxref=GeneID:72551506;Name=OPG111;gbkey=Gene;gene=OPG111;gene_biotype=protein_coding;locus_tag=NBT03_gp090;old_locus_tag=MPXV-M5312_HM12_Rivers-094 +NC_063383.1 RefSeq CDS 90265 91209 . + 0 ID=cds-YP_010377093.1;Parent=gene-NBT03_gp090;Dbxref=GenBank:YP_010377093.1,GeneID:72551506;Name=OPG111;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp096%3B DNA topoisomerase type I%3B similar to VACV-WR H6R and VACV-Cop H6R;gbkey=CDS;gene=OPG111;locus_tag=NBT03_gp090;product=DNA topoisomerase type I;protein_id=YP_010377093.1 +NC_063383.1 RefSeq gene 91247 91687 . + . ID=gene-NBT03_gp091;Dbxref=GeneID:72551507;Name=OPG112;gbkey=Gene;gene=OPG112;gene_biotype=protein_coding;locus_tag=NBT03_gp091;old_locus_tag=MPXV-M5312_HM12_Rivers-095 +NC_063383.1 RefSeq CDS 91247 91687 . + 0 ID=cds-YP_010377094.1;Parent=gene-NBT03_gp091;Dbxref=GenBank:YP_010377094.1,GeneID:72551507;Name=OPG112;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp097%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR H7R and VACV-Cop H7R;gbkey=CDS;gene=OPG112;locus_tag=NBT03_gp091;product=Late protein H7;protein_id=YP_010377094.1 +NC_063383.1 RefSeq gene 91731 94268 . + . ID=gene-NBT03_gp092;Dbxref=GeneID:72551508;Name=OPG113;gbkey=Gene;gene=OPG113;gene_biotype=protein_coding;locus_tag=NBT03_gp092;old_locus_tag=MPXV-M5312_HM12_Rivers-096 +NC_063383.1 RefSeq CDS 91731 94268 . + 0 ID=cds-YP_010377095.1;Parent=gene-NBT03_gp092;Dbxref=GenBank:YP_010377095.1,GeneID:72551508;Name=OPG113;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp098%3B mRNA capping enzyme%2C large subunit%3B RNA 5' triphosphatase and RNA guanylyl transferase activities%3B similar to VACV-WR E1R and VACV-Cop D1R;gbkey=CDS;gene=OPG113;locus_tag=NBT03_gp092;product=mRNA capping enzyme large subunit;protein_id=YP_010377095.1 +NC_063383.1 RefSeq gene 94227 94667 . - . ID=gene-NBT03_gp093;Dbxref=GeneID:72551509;Name=OPG114;gbkey=Gene;gene=OPG114;gene_biotype=protein_coding;locus_tag=NBT03_gp093;old_locus_tag=MPXV-M5312_HM12_Rivers-097 +NC_063383.1 RefSeq CDS 94227 94667 . - 0 ID=cds-YP_010377096.1;Parent=gene-NBT03_gp093;Dbxref=GenBank:YP_010377096.1,GeneID:72551509;Name=OPG114;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp099%3B virion core protein%3B similar to VACV-WR E2L and VACV-Cop D2L;gbkey=CDS;gene=OPG114;locus_tag=NBT03_gp093;product=Virion protein D2;protein_id=YP_010377096.1 +NC_063383.1 RefSeq gene 94660 95361 . + . ID=gene-NBT03_gp094;Dbxref=GeneID:72551510;Name=OPG115;gbkey=Gene;gene=OPG115;gene_biotype=protein_coding;locus_tag=NBT03_gp094;old_locus_tag=MPXV-M5312_HM12_Rivers-098 +NC_063383.1 RefSeq CDS 94660 95361 . + 0 ID=cds-YP_010377097.1;Parent=gene-NBT03_gp094;Dbxref=GenBank:YP_010377097.1,GeneID:72551510;Name=OPG115;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp100%3B virion core protein%3B similar to VACV-WR E3R and VACV-Cop D3R;gbkey=CDS;gene=OPG115;locus_tag=NBT03_gp094;product=Virion core protein D3;protein_id=YP_010377097.1 +NC_063383.1 RefSeq gene 95361 96017 . + . ID=gene-NBT03_gp095;Dbxref=GeneID:72551511;Name=OPG116;gbkey=Gene;gene=OPG116;gene_biotype=protein_coding;locus_tag=NBT03_gp095;old_locus_tag=MPXV-M5312_HM12_Rivers-099 +NC_063383.1 RefSeq CDS 95361 96017 . + 0 ID=cds-YP_010377098.1;Parent=gene-NBT03_gp095;Dbxref=GenBank:YP_010377098.1,GeneID:72551511;Name=OPG116;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp101%3B uracil DNA glycosylase%3B DNA polymerase processivity factor%3B similar to VACV-WR E4R and VACV-Cop D4R;gbkey=CDS;gene=OPG116;locus_tag=NBT03_gp095;product=Uracil DNA glycosylase superfamily;protein_id=YP_010377098.1 +NC_063383.1 RefSeq gene 96049 98406 . + . ID=gene-NBT03_gp096;Dbxref=GeneID:72551512;Name=OPG117;gbkey=Gene;gene=OPG117;gene_biotype=protein_coding;locus_tag=NBT03_gp096;old_locus_tag=MPXV-M5312_HM12_Rivers-100 +NC_063383.1 RefSeq CDS 96049 98406 . + 0 ID=cds-YP_010377099.1;Parent=gene-NBT03_gp096;Dbxref=GenBank:YP_010377099.1,GeneID:72551512;Name=OPG117;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp102%3B nucleic acid-independent nucleoside triphosphatase%3B NTPase%2C DNA primase%3B similar to VACV-WR E5R and VACV-Cop D5R;gbkey=CDS;gene=OPG117;locus_tag=NBT03_gp096;product=NTPase (1);protein_id=YP_010377099.1 +NC_063383.1 RefSeq gene 98446 100359 . + . ID=gene-NBT03_gp097;Dbxref=GeneID:72551513;Name=OPG118;gbkey=Gene;gene=OPG118;gene_biotype=protein_coding;locus_tag=NBT03_gp097;old_locus_tag=MPXV-M5312_HM12_Rivers-101 +NC_063383.1 RefSeq CDS 98446 100359 . + 0 ID=cds-YP_010377100.1;Parent=gene-NBT03_gp097;Dbxref=GenBank:YP_010377100.1,GeneID:72551513;Name=OPG118;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp103%3B early transcription factor%2C small subunit%2C VETF-s%3B Morphogenesis%3B similar to VACV-WR E6R and VACV-Cop D6R;gbkey=CDS;gene=OPG118;locus_tag=NBT03_gp097;product=Early transcription factor 70 kDa subunit;protein_id=YP_010377100.1 +NC_063383.1 RefSeq gene 100386 100871 . + . ID=gene-NBT03_gp098;Dbxref=GeneID:72551514;Name=OPG119;gbkey=Gene;gene=OPG119;gene_biotype=protein_coding;locus_tag=NBT03_gp098;old_locus_tag=MPXV-M5312_HM12_Rivers-102 +NC_063383.1 RefSeq CDS 100386 100871 . + 0 ID=cds-YP_010377101.1;Parent=gene-NBT03_gp098;Dbxref=GenBank:YP_010377101.1,GeneID:72551514;Name=OPG119;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp104%3B RNA polymerase%2C 18 kDa subunit (RPO18)%3B similar to VACV-WR E7R and VACV-Cop D7R;gbkey=CDS;gene=OPG119;locus_tag=NBT03_gp098;product=RNA polymerase subunit RPO18;protein_id=YP_010377101.1 +NC_063383.1 RefSeq gene 100834 101748 . - . ID=gene-NBT03_gp099;Dbxref=GeneID:72551515;Name=OPG120;gbkey=Gene;gene=OPG120;gene_biotype=protein_coding;locus_tag=NBT03_gp099;old_locus_tag=MPXV-M5312_HM12_Rivers-103 +NC_063383.1 RefSeq CDS 100834 101748 . - 0 ID=cds-YP_010377102.1;Parent=gene-NBT03_gp099;Dbxref=GenBank:YP_010377102.1,GeneID:72551515;Name=OPG120;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp105%3B IMV surface membrane 32 kDa protein%3B binding to cell surface chondroitin sulfate%3B IMV adsorption to cell surface%3B GAG-binding IMV membrane protein%3B similar to VACV-WR E8L and VACV-Cop D8L;gbkey=CDS;gene=OPG120;locus_tag=NBT03_gp099;product=Carbonic anhydrase;protein_id=YP_010377102.1 +NC_063383.1 RefSeq gene 101790 102431 . + . ID=gene-NBT03_gp100;Dbxref=GeneID:72551516;Name=OPG121;gbkey=Gene;gene=OPG121;gene_biotype=protein_coding;locus_tag=NBT03_gp100;old_locus_tag=MPXV-M5312_HM12_Rivers-104 +NC_063383.1 RefSeq CDS 101790 102431 . + 0 ID=cds-YP_010377103.1;Parent=gene-NBT03_gp100;Dbxref=GenBank:YP_010377103.1,GeneID:72551516;Name=OPG121;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp106%3B Mut-like%3B mRNA decapping enzyme%3B similar to VACV-WR E9R and VACV-Cop D9R;gbkey=CDS;gene=OPG121;locus_tag=NBT03_gp100;product=NUDIX domain protein;protein_id=YP_010377103.1 +NC_063383.1 RefSeq gene 102428 103174 . + . ID=gene-NBT03_gp101;Dbxref=GeneID:72551517;Name=OPG122;gbkey=Gene;gene=OPG122;gene_biotype=protein_coding;locus_tag=NBT03_gp101;old_locus_tag=MPXV-M5312_HM12_Rivers-105 +NC_063383.1 RefSeq CDS 102428 103174 . + 0 ID=cds-YP_010377104.1;Parent=gene-NBT03_gp101;Dbxref=GenBank:YP_010377104.1,GeneID:72551517;Name=OPG122;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp107%3B down regulation of gene expression%3B Mut-like%3B mRNA decapping enzyme%3B similar to VACV-WR E10R and VACV-Cop D10R;gbkey=CDS;gene=OPG122;locus_tag=NBT03_gp101;product=MutT motif protein;protein_id=YP_010377104.1 +NC_063383.1 RefSeq gene 103175 105070 . - . ID=gene-NBT03_gp102;Dbxref=GeneID:72551518;Name=OPG123;gbkey=Gene;gene=OPG123;gene_biotype=protein_coding;locus_tag=NBT03_gp102;old_locus_tag=MPXV-M5312_HM12_Rivers-106 +NC_063383.1 RefSeq CDS 103175 105070 . - 0 ID=cds-YP_010377105.1;Parent=gene-NBT03_gp102;Dbxref=GenBank:YP_010377105.1,GeneID:72551518;Name=OPG123;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp108%3B nucleoside triphosphate phosphohydrolase I%2C NPH I%3B DNA-dependent ATPase%3B early gene transcription termination factor%3B similar to VACV-WR E11L and VACV-Cop D11L;gbkey=CDS;gene=OPG123;locus_tag=NBT03_gp102;product=Nucleoside triphosphatase I;protein_id=YP_010377105.1 +NC_063383.1 RefSeq gene 105105 105968 . - . ID=gene-NBT03_gp103;Dbxref=GeneID:72551519;Name=OPG124;gbkey=Gene;gene=OPG124;gene_biotype=protein_coding;locus_tag=NBT03_gp103;old_locus_tag=MPXV-M5312_HM12_Rivers-107 +NC_063383.1 RefSeq CDS 105105 105968 . - 0 ID=cds-YP_010377106.1;Parent=gene-NBT03_gp103;Dbxref=GenBank:YP_010377106.1,GeneID:72551519;Name=OPG124;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp109%3B mRNA capping enzyme small subunit%3B mRNA (guanine-N7-)-methyl-transferase%3B transcription initiation factor%3B similar to VACV-WR E12L and VACV-Cop D12L;gbkey=CDS;gene=OPG124;locus_tag=NBT03_gp103;product=mRNA capping enzyme small subunit;protein_id=YP_010377106.1 +NC_063383.1 RefSeq gene 105999 107654 . - . ID=gene-NBT03_gp104;Dbxref=GeneID:72551520;Name=OPG125;gbkey=Gene;gene=OPG125;gene_biotype=protein_coding;locus_tag=NBT03_gp104;old_locus_tag=MPXV-M5312_HM12_Rivers-108 +NC_063383.1 RefSeq CDS 105999 107654 . - 0 ID=cds-YP_010377107.1;Parent=gene-NBT03_gp104;Dbxref=GenBank:YP_010377107.1,GeneID:72551520;Name=OPG125;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp110%3B protein needed for the formation of immature IMV surface membrane%3B Trimeric virion coat protein (rifampicin res)%3B similar to VACV-WR E13L and VACV-Cop D13L;gbkey=CDS;gene=OPG125;locus_tag=NBT03_gp104;product=Rifampicin resistance protein;protein_id=YP_010377107.1 +NC_063383.1 RefSeq gene 107678 108130 . - . ID=gene-NBT03_gp105;Dbxref=GeneID:72551521;Name=OPG126;gbkey=Gene;gene=OPG126;gene_biotype=protein_coding;locus_tag=NBT03_gp105;old_locus_tag=MPXV-M5312_HM12_Rivers-109 +NC_063383.1 RefSeq CDS 107678 108130 . - 0 ID=cds-YP_010377108.1;Parent=gene-NBT03_gp105;Dbxref=GenBank:YP_010377108.1,GeneID:72551521;Name=OPG126;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp111%3B late gene transcription factor%2C VLTF-2%3B similar to VACV-WR A1L and VACV-Cop A1L;gbkey=CDS;gene=OPG126;locus_tag=NBT03_gp105;product=Late transcription factor VLTF-2 (2);protein_id=YP_010377108.1 +NC_063383.1 RefSeq gene 108151 108825 . - . ID=gene-NBT03_gp106;Dbxref=GeneID:72551522;Name=OPG127;gbkey=Gene;gene=OPG127;gene_biotype=protein_coding;locus_tag=NBT03_gp106;old_locus_tag=MPXV-M5312_HM12_Rivers-110 +NC_063383.1 RefSeq CDS 108151 108825 . - 0 ID=cds-YP_010377109.1;Parent=gene-NBT03_gp106;Dbxref=GenBank:YP_010377109.1,GeneID:72551522;Name=OPG127;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp112%3B late gene transcription factor%2C VLTF-3%3B zinc binding%3B similar to VACV-WR A2L and VACV-Cop A2L;gbkey=CDS;gene=OPG127;locus_tag=NBT03_gp106;product=Late transcription factor VLTF-3 (1);protein_id=YP_010377109.1 +NC_063383.1 RefSeq gene 108822 109055 . - . ID=gene-NBT03_gp107;Dbxref=GeneID:72551523;Name=OPG128;gbkey=Gene;gene=OPG128;gene_biotype=protein_coding;locus_tag=NBT03_gp107;old_locus_tag=MPXV-M5312_HM12_Rivers-111 +NC_063383.1 RefSeq CDS 108822 109055 . - 0 ID=cds-YP_010377110.1;Parent=gene-NBT03_gp107;Dbxref=GenBank:YP_010377110.1,GeneID:72551523;Name=OPG128;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp113%3B S-S bond formation pathway protein%3B similar to VACV-WR A3L and VACV-Cop A2.5L;gbkey=CDS;gene=OPG128;locus_tag=NBT03_gp107;product=S-S bond formation pathway protein;protein_id=YP_010377110.1 +NC_063383.1 RefSeq gene 109070 111004 . - . ID=gene-NBT03_gp108;Dbxref=GeneID:72551524;Name=OPG129;gbkey=Gene;gene=OPG129;gene_biotype=protein_coding;locus_tag=NBT03_gp108;old_locus_tag=MPXV-M5312_HM12_Rivers-112 +NC_063383.1 RefSeq CDS 109070 111004 . - 0 ID=cds-YP_010377111.1;Parent=gene-NBT03_gp108;Dbxref=GenBank:YP_010377111.1,GeneID:72551524;Name=OPG129;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp114%3B major virion core protein p4b%3B P4b precursor%3B similar to VACV-WR A4L and VACV-Cop A3L;gbkey=CDS;gene=OPG129;locus_tag=NBT03_gp108;product=Virion core protein P4b;protein_id=YP_010377111.1 +NC_063383.1 RefSeq gene 111057 111902 . - . ID=gene-NBT03_gp109;Dbxref=GeneID:72551525;Name=OPG130;gbkey=Gene;gene=OPG130;gene_biotype=protein_coding;locus_tag=NBT03_gp109;old_locus_tag=MPXV-M5312_HM12_Rivers-113 +NC_063383.1 RefSeq CDS 111057 111902 . - 0 ID=cds-YP_010377112.1;Parent=gene-NBT03_gp109;Dbxref=GenBank:YP_010377112.1,GeneID:72551525;Name=OPG130;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp115%3B 39 kDa immunodominant virion core protein needed for the progression of IV to infectious IMV%3B 39kDa virion core protein%3B similar to VACV-WR A5L and VACV-Cop A4L;gbkey=CDS;gene=OPG130;locus_tag=NBT03_gp109;product=A5L protein-like;protein_id=YP_010377112.1 +NC_063383.1 RefSeq gene 111940 112425 . + . ID=gene-NBT03_gp110;Dbxref=GeneID:72551526;Name=OPG131;gbkey=Gene;gene=OPG131;gene_biotype=protein_coding;locus_tag=NBT03_gp110;old_locus_tag=MPXV-M5312_HM12_Rivers-114 +NC_063383.1 RefSeq CDS 111940 112425 . + 0 ID=cds-YP_010377113.1;Parent=gene-NBT03_gp110;Dbxref=GenBank:YP_010377113.1,GeneID:72551526;Name=OPG131;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp116%3B precursor of RNA polymerase 22 kDa and 21 kDa%3B RNA polymerase subunit (RPO19)%3B similar to VACV-WR A6R and VACV-Cop A5R;gbkey=CDS;gene=OPG131;locus_tag=NBT03_gp110;product=DNA-directed RNA polymerase 19 kDa subunit;protein_id=YP_010377113.1 +NC_063383.1 RefSeq gene 112422 113540 . - . ID=gene-NBT03_gp111;Dbxref=GeneID:72551527;Name=OPG132;gbkey=Gene;gene=OPG132;gene_biotype=protein_coding;locus_tag=NBT03_gp111;old_locus_tag=MPXV-M5312_HM12_Rivers-115 +NC_063383.1 RefSeq CDS 112422 113540 . - 0 ID=cds-YP_010377114.1;Parent=gene-NBT03_gp111;Dbxref=GenBank:YP_010377114.1,GeneID:72551527;Name=OPG132;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp117%3B Viral membrane assembly proteins (VMAP)%2C core protein%3B similar to VACV-WR A7L and VACV-Cop A6L;gbkey=CDS;gene=OPG132;locus_tag=NBT03_gp111;product=Virion morphogenesis protein;protein_id=YP_010377114.1 +NC_063383.1 RefSeq gene 113564 115696 . - . ID=gene-NBT03_gp112;Dbxref=GeneID:72551528;Name=OPG133;gbkey=Gene;gene=OPG133;gene_biotype=protein_coding;locus_tag=NBT03_gp112;old_locus_tag=MPXV-M5312_HM12_Rivers-116 +NC_063383.1 RefSeq CDS 113564 115696 . - 0 ID=cds-YP_010377115.1;Parent=gene-NBT03_gp112;Dbxref=GenBank:YP_010377115.1,GeneID:72551528;Name=OPG133;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp118%3B early transcription factor%2C large subunit%2C VETF-L%3B needed for morphogenesis of the virion core%3B similar to VACV-WR A8L and VACV-Cop A7L;gbkey=CDS;gene=OPG133;locus_tag=NBT03_gp112;product=Early transcription factor 82 kDa subunit;protein_id=YP_010377115.1 +NC_063383.1 RefSeq gene 115750 116628 . + . ID=gene-NBT03_gp113;Dbxref=GeneID:72551529;Name=OPG134;gbkey=Gene;gene=OPG134;gene_biotype=protein_coding;locus_tag=NBT03_gp113;old_locus_tag=MPXV-M5312_HM12_Rivers-117 +NC_063383.1 RefSeq CDS 115750 116628 . + 0 ID=cds-YP_010377116.1;Parent=gene-NBT03_gp113;Dbxref=GenBank:YP_010377116.1,GeneID:72551529;Name=OPG134;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp119%3B intermediate transcription factor%2C VITF-3 34kda subunit%2C 34 kDa%3B similar to VACV-WR A9R and VACV-Cop A8R;gbkey=CDS;gene=OPG134;locus_tag=NBT03_gp113;product=Intermediate transcription factor VITF-3 (1);protein_id=YP_010377116.1 +NC_063383.1 RefSeq gene 116609 116911 . - . ID=gene-NBT03_gp114;Dbxref=GeneID:72551530;Name=OPG135;gbkey=Gene;gene=OPG135;gene_biotype=protein_coding;locus_tag=NBT03_gp114;old_locus_tag=MPXV-M5312_HM12_Rivers-118 +NC_063383.1 RefSeq CDS 116609 116911 . - 0 ID=cds-YP_010377117.1;Parent=gene-NBT03_gp114;Dbxref=GenBank:YP_010377117.1,GeneID:72551530;Name=OPG135;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp120%3B Viral membrane associated%2C early morphogenesis protein%3B similar to VACV-WR A10L and VACV-Cop A9L;gbkey=CDS;gene=OPG135;locus_tag=NBT03_gp114;product=IMV membrane protein A9;protein_id=YP_010377117.1 +NC_063383.1 RefSeq gene 116912 119587 . - . ID=gene-NBT03_gp115;Dbxref=GeneID:72551531;Name=OPG136;gbkey=Gene;gene=OPG136;gene_biotype=protein_coding;locus_tag=NBT03_gp115;old_locus_tag=MPXV-M5312_HM12_Rivers-119 +NC_063383.1 RefSeq CDS 116912 119587 . - 0 ID=cds-YP_010377118.1;Parent=gene-NBT03_gp115;Dbxref=GenBank:YP_010377118.1,GeneID:72551531;Name=OPG136;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp121%3B major virion core protein p4a%3B P4a precursor%3B similar to VACV-WR A11L and VACV-Cop A10L;gbkey=CDS;gene=OPG136;locus_tag=NBT03_gp115;product=Virion core protein P4a;protein_id=YP_010377118.1 +NC_063383.1 RefSeq gene 119602 120558 . + . ID=gene-NBT03_gp116;Dbxref=GeneID:72551532;Name=OPG137;gbkey=Gene;gene=OPG137;gene_biotype=protein_coding;locus_tag=NBT03_gp116;old_locus_tag=MPXV-M5312_HM12_Rivers-120 +NC_063383.1 RefSeq CDS 119602 120558 . + 0 ID=cds-YP_010377119.1;Parent=gene-NBT03_gp116;Dbxref=GenBank:YP_010377119.1,GeneID:72551532;Name=OPG137;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp122%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR A12R and VACV-Cop A11R;gbkey=CDS;gene=OPG137;locus_tag=NBT03_gp116;product=Viral membrane formation protein;protein_id=YP_010377119.1 +NC_063383.1 RefSeq gene 120560 121132 . - . ID=gene-NBT03_gp117;Dbxref=GeneID:72551533;Name=OPG138;gbkey=Gene;gene=OPG138;gene_biotype=protein_coding;locus_tag=NBT03_gp117;old_locus_tag=MPXV-M5312_HM12_Rivers-121 +NC_063383.1 RefSeq CDS 120560 121132 . - 0 ID=cds-YP_010377120.1;Parent=gene-NBT03_gp117;Dbxref=GenBank:YP_010377120.1,GeneID:72551533;Name=OPG138;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp123%3B Virion core and cleavage processing protein%3B similar to VACV-WR A13L and VACV-Cop A12L;gbkey=CDS;gene=OPG138;locus_tag=NBT03_gp117;product=A12 protein;protein_id=YP_010377120.1 +NC_063383.1 RefSeq gene 121156 121368 . - . ID=gene-NBT03_gp118;Dbxref=GeneID:72551534;Name=OPG139;gbkey=Gene;gene=OPG139;gene_biotype=protein_coding;locus_tag=NBT03_gp118;old_locus_tag=MPXV-M5312_HM12_Rivers-122 +NC_063383.1 RefSeq CDS 121156 121368 . - 0 ID=cds-YP_010377121.1;Parent=gene-NBT03_gp118;Dbxref=GenBank:YP_010377121.1,GeneID:72551534;Name=OPG139;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp124%3B IMV inner and outer membrane protein%3B virion maturation%3B similar to VACV-WR A14L and VACV-Cop A13L;gbkey=CDS;gene=OPG139;locus_tag=NBT03_gp118;product=IMV membrane protein A13L;protein_id=YP_010377121.1 +NC_063383.1 RefSeq gene 121474 121746 . - . ID=gene-NBT03_gp119;Dbxref=GeneID:72551535;Name=OPG140;gbkey=Gene;gene=OPG140;gene_biotype=protein_coding;locus_tag=NBT03_gp119;old_locus_tag=MPXV-M5312_HM12_Rivers-123 +NC_063383.1 RefSeq CDS 121474 121746 . - 0 ID=cds-YP_010377122.1;Parent=gene-NBT03_gp119;Dbxref=GenBank:YP_010377122.1,GeneID:72551535;Name=OPG140;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp125%3B IMV inner membrane protein%3B Essential IMV membrane protein%3B similar to VACV-WR A15L and VACV-Cop A14L;gbkey=CDS;gene=OPG140;locus_tag=NBT03_gp119;product=IMV membrane protein A14;protein_id=YP_010377122.1 +NC_063383.1 RefSeq gene 121763 121924 . - . ID=gene-NBT03_gp120;Dbxref=GeneID:72551536;Name=OPG141;gbkey=Gene;gene=OPG141;gene_biotype=protein_coding;locus_tag=NBT03_gp120;old_locus_tag=MPXV-M5312_HM12_Rivers-124 +NC_063383.1 RefSeq CDS 121763 121924 . - 0 ID=cds-YP_010377123.1;Parent=gene-NBT03_gp120;Dbxref=GenBank:YP_010377123.1,GeneID:72551536;Name=OPG141;Note=Taxonomic breadth: chordopoxvirinae%3B Non-essential IMV membrane protein%3B similar to VACV-WR A15.5L and VACV-Cop A14.5L;gbkey=CDS;gene=OPG141;locus_tag=NBT03_gp120;product=DUF1029 domain protein;protein_id=YP_010377123.1 +NC_063383.1 RefSeq gene 121914 122198 . - . ID=gene-NBT03_gp121;Dbxref=GeneID:72551537;Name=OPG142;gbkey=Gene;gene=OPG142;gene_biotype=protein_coding;locus_tag=NBT03_gp121;old_locus_tag=MPXV-M5312_HM12_Rivers-125 +NC_063383.1 RefSeq CDS 121914 122198 . - 0 ID=cds-YP_010377124.1;Parent=gene-NBT03_gp121;Dbxref=GenBank:YP_010377124.1,GeneID:72551537;Name=OPG142;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp126%3B Core protein%3B similar to VACV-WR A16L and VACV-Cop A15L;gbkey=CDS;gene=OPG142;locus_tag=NBT03_gp121;product=Core protein A15;protein_id=YP_010377124.1 +NC_063383.1 RefSeq gene 122182 123315 . - . ID=gene-NBT03_gp122;Dbxref=GeneID:72551538;Name=OPG143;gbkey=Gene;gene=OPG143;gene_biotype=protein_coding;locus_tag=NBT03_gp122;old_locus_tag=MPXV-M5312_HM12_Rivers-126 +NC_063383.1 RefSeq CDS 122182 123315 . - 0 ID=cds-YP_010377125.1;Parent=gene-NBT03_gp122;Dbxref=GenBank:YP_010377125.1,GeneID:72551538;Name=OPG143;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp127%3B soluble myristylated protein%3B essential for entry/fusion%3B similar to VACV-WR A17L and VACV-Cop A16L;gbkey=CDS;gene=OPG143;locus_tag=NBT03_gp122;product=Myristylated protein;protein_id=YP_010377125.1 +NC_063383.1 RefSeq gene 123318 123932 . - . ID=gene-NBT03_gp123;Dbxref=GeneID:72551539;Name=OPG144;gbkey=Gene;gene=OPG144;gene_biotype=protein_coding;locus_tag=NBT03_gp123;old_locus_tag=MPXV-M5312_HM12_Rivers-127 +NC_063383.1 RefSeq CDS 123318 123932 . - 0 ID=cds-YP_010377126.1;Parent=gene-NBT03_gp123;Dbxref=GenBank:YP_010377126.1,GeneID:72551539;Name=OPG144;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp128%3B IMV surface membrane protein%3B early function in virion morphgenesis%3B similar to VACV-WR A18L and VACV-Cop A17L;gbkey=CDS;gene=OPG144;locus_tag=NBT03_gp123;product=IMV membrane protein P21;protein_id=YP_010377126.1 +NC_063383.1 RefSeq gene 123947 125425 . + . ID=gene-NBT03_gp124;Dbxref=GeneID:72551540;Name=OPG145;gbkey=Gene;gene=OPG145;gene_biotype=protein_coding;locus_tag=NBT03_gp124;old_locus_tag=MPXV-M5312_HM12_Rivers-128 +NC_063383.1 RefSeq CDS 123947 125425 . + 0 ID=cds-YP_010377127.1;Parent=gene-NBT03_gp124;Dbxref=GenBank:YP_010377127.1,GeneID:72551540;Name=OPG145;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp129%3B virion core associated DNA helicase%3B post-replicative negative transcription elongation factor%3B transcript release factor%3B similar to VACV-WR A19R and VACV-Cop A18R;gbkey=CDS;gene=OPG145;locus_tag=NBT03_gp124;product=DNA helicase;protein_id=YP_010377127.1 +NC_063383.1 RefSeq gene 125406 125639 . - . ID=gene-NBT03_gp125;Dbxref=GeneID:72551541;Name=OPG146;gbkey=Gene;gene=OPG146;gene_biotype=protein_coding;locus_tag=NBT03_gp125;old_locus_tag=MPXV-M5312_HM12_Rivers-129 +NC_063383.1 RefSeq CDS 125406 125639 . - 0 ID=cds-YP_010377128.1;Parent=gene-NBT03_gp125;Dbxref=GenBank:YP_010377128.1,GeneID:72551541;Name=OPG146;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp130%3B Zinc finger-like protein%3B similar to VACV-WR A20L and VACV-Cop A19L;gbkey=CDS;gene=OPG146;locus_tag=NBT03_gp125;product=Zinc finger-like protein (1);protein_id=YP_010377128.1 +NC_063383.1 RefSeq gene 125640 125987 . - . ID=gene-NBT03_gp126;Dbxref=GeneID:72551542;Name=OPG147;gbkey=Gene;gene=OPG147;gene_biotype=protein_coding;locus_tag=NBT03_gp126;old_locus_tag=MPXV-M5312_HM12_Rivers-130 +NC_063383.1 RefSeq CDS 125640 125987 . - 0 ID=cds-YP_010377129.1;Parent=gene-NBT03_gp126;Dbxref=GenBank:YP_010377129.1,GeneID:72551542;Name=OPG147;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp131%3B IMV membrane protein%2C entry/fusion complex component%3B similar to VACV-WR A21L and VACV-Cop A21L;gbkey=CDS;gene=OPG147;locus_tag=NBT03_gp126;product=IMV membrane protein A21;protein_id=YP_010377129.1 +NC_063383.1 RefSeq gene 125986 127266 . + . ID=gene-NBT03_gp127;Dbxref=GeneID:72551543;Name=OPG148;gbkey=Gene;gene=OPG148;gene_biotype=protein_coding;locus_tag=NBT03_gp127;old_locus_tag=MPXV-M5312_HM12_Rivers-131 +NC_063383.1 RefSeq CDS 125986 127266 . + 0 ID=cds-YP_010377130.1;Parent=gene-NBT03_gp127;Dbxref=GenBank:YP_010377130.1,GeneID:72551543;Name=OPG148;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp132%3B processivity factor for the viral DNA polymerase%2C VPF%3B similar to VACV-WR A22R and VACV-Cop A20R;gbkey=CDS;gene=OPG148;locus_tag=NBT03_gp127;product=DNA polymerase processivity factor;protein_id=YP_010377130.1 +NC_063383.1 RefSeq gene 127196 127759 . + . ID=gene-NBT03_gp128;Dbxref=GeneID:72551544;Name=OPG149;gbkey=Gene;gene=OPG149;gene_biotype=protein_coding;locus_tag=NBT03_gp128;old_locus_tag=MPXV-M5312_HM12_Rivers-132 +NC_063383.1 RefSeq CDS 127196 127759 . + 0 ID=cds-YP_010377131.1;Parent=gene-NBT03_gp128;Dbxref=GenBank:YP_010377131.1,GeneID:72551544;Name=OPG149;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp133%3B Holliday junction resolvase%3B similar to VACV-WR A23R and VACV-Cop A22R;gbkey=CDS;gene=OPG149;locus_tag=NBT03_gp128;product=Holliday junction resolvase;protein_id=YP_010377131.1 +NC_063383.1 RefSeq gene 127779 128927 . + . ID=gene-NBT03_gp129;Dbxref=GeneID:72551545;Name=OPG150;gbkey=Gene;gene=OPG150;gene_biotype=protein_coding;locus_tag=NBT03_gp129;old_locus_tag=MPXV-M5312_HM12_Rivers-133 +NC_063383.1 RefSeq CDS 127779 128927 . + 0 ID=cds-YP_010377132.1;Parent=gene-NBT03_gp129;Dbxref=GenBank:YP_010377132.1,GeneID:72551545;Name=OPG150;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp134%3B intermediate transcription factor%2C VITF-3%2C 45 kDa subunit%3B similar to VACV-WR A24R and VACV-Cop A23R;gbkey=CDS;gene=OPG150;locus_tag=NBT03_gp129;product=Intermediate transcription factor VITF-3 (2);protein_id=YP_010377132.1 +NC_063383.1 RefSeq gene 128924 132418 . + . ID=gene-NBT03_gp130;Dbxref=GeneID:72551546;Name=OPG151;gbkey=Gene;gene=OPG151;gene_biotype=protein_coding;locus_tag=NBT03_gp130;old_locus_tag=MPXV-M5312_HM12_Rivers-134 +NC_063383.1 RefSeq CDS 128924 132418 . + 0 ID=cds-YP_010377133.1;Parent=gene-NBT03_gp130;Dbxref=GenBank:YP_010377133.1,GeneID:72551546;Name=OPG151;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp135%3B RNA polymerase%2C 132 kDa subunit (RPO132)%3B similar to VACV-WR A25R and VACV-Cop A24R;gbkey=CDS;gene=OPG151;locus_tag=NBT03_gp130;product=DNA-dependent RNA polymerase subunit rpo132;protein_id=YP_010377133.1 +NC_063383.1 RefSeq sequence_feature 132396 136092 . - . ID=id-NC_063383.1:132396..136092;exon_number=OPG152;gbkey=misc_feature;number=OPG152 +NC_063383.1 RefSeq gene 136138 137667 . - . ID=gene-NBT03_gp131;Dbxref=GeneID:72551547;Name=OPG153;gbkey=Gene;gene=OPG153;gene_biotype=protein_coding;locus_tag=NBT03_gp131;old_locus_tag=MPXV-M5312_HM12_Rivers-137 +NC_063383.1 RefSeq CDS 136138 137667 . - 0 ID=cds-YP_010377134.1;Parent=gene-NBT03_gp131;Dbxref=GenBank:YP_010377134.1,GeneID:72551547;Name=OPG153;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp138%3B major component of IMV surface tubules%3B A-type inclusion protein%3B P4c precursor%3B similar to VACV-WR A28L and VACV-Cop A26L;gbkey=CDS;gene=OPG153;locus_tag=NBT03_gp131;product=Orthopoxvirus A26L/A30L protein;protein_id=YP_010377134.1 +NC_063383.1 RefSeq gene 137718 138050 . - . ID=gene-NBT03_gp132;Dbxref=GeneID:72551548;Name=OPG154;gbkey=Gene;gene=OPG154;gene_biotype=protein_coding;locus_tag=NBT03_gp132;old_locus_tag=MPXV-M5312_HM12_Rivers-138 +NC_063383.1 RefSeq CDS 137718 138050 . - 0 ID=cds-YP_010377135.1;Parent=gene-NBT03_gp132;Dbxref=GenBank:YP_010377135.1,GeneID:72551548;Name=OPG154;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp139%3B IMV surface membrane 14 kDa fusion protein%3B binding to cell surface heparan%3B similar to VACV-WR A29L and VACV-Cop A27L;gbkey=CDS;gene=OPG154;locus_tag=NBT03_gp132;product=IMV surface fusion protein;protein_id=YP_010377135.1 +NC_063383.1 RefSeq gene 138051 138491 . - . ID=gene-NBT03_gp133;Dbxref=GeneID:72551549;Name=OPG155;gbkey=Gene;gene=OPG155;gene_biotype=protein_coding;locus_tag=NBT03_gp133;old_locus_tag=MPXV-M5312_HM12_Rivers-139 +NC_063383.1 RefSeq CDS 138051 138491 . - 0 ID=cds-YP_010377136.1;Parent=gene-NBT03_gp133;Dbxref=GenBank:YP_010377136.1,GeneID:72551549;Name=OPG155;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp140%3B IMV MP/Virus entry%3B similar to VACV-WR A30L and VACV-Cop A28L;gbkey=CDS;gene=OPG155;locus_tag=NBT03_gp133;product=Envelope protein A28 homolog;protein_id=YP_010377136.1 +NC_063383.1 RefSeq gene 138492 139409 . - . ID=gene-NBT03_gp134;Dbxref=GeneID:72551550;Name=OPG156;gbkey=Gene;gene=OPG156;gene_biotype=protein_coding;locus_tag=NBT03_gp134;old_locus_tag=MPXV-M5312_HM12_Rivers-140 +NC_063383.1 RefSeq CDS 138492 139409 . - 0 ID=cds-YP_010377137.1;Parent=gene-NBT03_gp134;Dbxref=GenBank:YP_010377137.1,GeneID:72551550;Name=OPG156;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp141%3B RNA polymerase%2C 35 kDa subunit (RPO35)%3B similar to VACV-WR A31L and VACV-Cop A29L;gbkey=CDS;gene=OPG156;locus_tag=NBT03_gp134;product=DNA-directed RNA polymerase 35 kDa subunit;protein_id=YP_010377137.1 +NC_063383.1 RefSeq gene 139372 139608 . - . ID=gene-NBT03_gp135;Dbxref=GeneID:72551551;Name=OPG157;gbkey=Gene;gene=OPG157;gene_biotype=protein_coding;locus_tag=NBT03_gp135;old_locus_tag=MPXV-M5312_HM12_Rivers-141 +NC_063383.1 RefSeq CDS 139372 139608 . - 0 ID=cds-YP_010377138.1;Parent=gene-NBT03_gp135;Dbxref=GenBank:YP_010377138.1,GeneID:72551551;Name=OPG157;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp142%3B IMV protein%3B similar to VACV-WR A32L and VACV-Cop A30L;gbkey=CDS;gene=OPG157;locus_tag=NBT03_gp135;product=IMV membrane protein A30;protein_id=YP_010377138.1 +NC_063383.1 RefSeq gene 139641 139769 . - . ID=gene-NBT03_gp136;Dbxref=GeneID:72551552;Name=OPG158;gbkey=Gene;gene=OPG158;gene_biotype=protein_coding;locus_tag=NBT03_gp136;old_locus_tag=MPXV-M5312_HM12_Rivers-142 +NC_063383.1 RefSeq CDS 139641 139769 . - 0 ID=cds-YP_010377139.1;Parent=gene-NBT03_gp136;Dbxref=GenBank:YP_010377139.1,GeneID:72551552;Name=OPG158;Note=Viral membrane assembly proteins (VMAP)%3B similar to VACV-Cop A30.5L;gbkey=CDS;gene=OPG158;locus_tag=NBT03_gp136;product=A32.5L;protein_id=YP_010377139.1 +NC_063383.1 RefSeq gene 139768 140205 . + . ID=gene-NBT03_gp137;Dbxref=GeneID:72551553;Name=OPG159;gbkey=Gene;gene=OPG159;gene_biotype=protein_coding;locus_tag=NBT03_gp137;old_locus_tag=MPXV-M5312_HM12_Rivers-143 +NC_063383.1 RefSeq CDS 139768 140205 . + 0 ID=cds-YP_010377140.1;Parent=gene-NBT03_gp137;Dbxref=GenBank:YP_010377140.1,GeneID:72551553;Name=OPG159;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp143%3B Hypothetical protein%3B similar to VACV-WR A33R and VACV-Cop A31R;gbkey=CDS;gene=OPG159;locus_tag=NBT03_gp137;product=CPXV166 protein;protein_id=YP_010377140.1 +NC_063383.1 RefSeq gene 140172 141074 . - . ID=gene-NBT03_gp138;Dbxref=GeneID:72551554;Name=OPG160;gbkey=Gene;gene=OPG160;gene_biotype=protein_coding;locus_tag=NBT03_gp138;old_locus_tag=MPXV-M5312_HM12_Rivers-144 +NC_063383.1 RefSeq CDS 140172 141074 . - 0 ID=cds-YP_010377141.1;Parent=gene-NBT03_gp138;Dbxref=GenBank:YP_010377141.1,GeneID:72551554;Name=OPG160;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp144%3B DNA packaging into virion%3B NTP-binding motif A%3B ATPase/DNA packaging protein%3B similar to VACV-WR A34L and VACV-Cop A32L;gbkey=CDS;gene=OPG160;locus_tag=NBT03_gp138;product=ATPase A32;protein_id=YP_010377141.1 +NC_063383.1 RefSeq gene 141102 141647 . + . ID=gene-NBT03_gp139;Dbxref=GeneID:72551555;Name=OPG161;gbkey=Gene;gene=OPG161;gene_biotype=protein_coding;locus_tag=NBT03_gp139;old_locus_tag=MPXV-M5312_HM12_Rivers-145 +NC_063383.1 RefSeq CDS 141102 141647 . + 0 ID=cds-YP_010377142.1;Parent=gene-NBT03_gp139;Dbxref=GenBank:YP_010377142.1,GeneID:72551555;Name=OPG161;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp145%3B EEV envelope glycoprotein%2C needed for formation of actin-containing microvilli and cell-to-cell spread of virion%3B interacts with VAC A36R%3B EEV membrane phosphoglycoprotein%2C C-type lectin-like domain%3B similar to VACV-WR A35R and VACV-Cop A33R;gbkey=CDS;gene=OPG161;locus_tag=NBT03_gp139;product=EEV glycoprotein (1);protein_id=YP_010377142.1 +NC_063383.1 RefSeq gene 141652 142158 . + . ID=gene-NBT03_gp140;Dbxref=GeneID:72551556;Name=OPG162;gbkey=Gene;gene=OPG162;gene_biotype=protein_coding;locus_tag=NBT03_gp140;old_locus_tag=MPXV-M5312_HM12_Rivers-146 +NC_063383.1 RefSeq CDS 141652 142158 . + 0 ID=cds-YP_010377143.1;Parent=gene-NBT03_gp140;Dbxref=GenBank:YP_010377143.1,GeneID:72551556;Name=OPG162;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp146%3B EEV envelope glycoprotein%2C lectin-like%3B required for infectivity of EEV%2C formation of actin-containing microvilli%2C and cell-to-cell spread of virion%3B C-type lectin-like IEV/EEV glycoprotein%3B similar to VACV-WR A36R and VACV-Cop A34R;gbkey=CDS;gene=OPG162;locus_tag=NBT03_gp140;product=EEV glycoprotein (2);protein_id=YP_010377143.1 +NC_063383.1 RefSeq gene 142202 142732 . + . ID=gene-NBT03_gp141;Dbxref=GeneID:72551557;Name=OPG163;gbkey=Gene;gene=OPG163;gene_biotype=protein_coding;locus_tag=NBT03_gp141;old_locus_tag=MPXV-M5312_HM12_Rivers-147 +NC_063383.1 RefSeq CDS 142202 142732 . + 0 ID=cds-YP_010377144.1;Parent=gene-NBT03_gp141;Dbxref=GenBank:YP_010377144.1,GeneID:72551557;Name=OPG163;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp147%3B MHC class II antigen presentation inhibitor%3B similar to VACV-WR A37R and VACV-Cop A35R;gbkey=CDS;gene=OPG163;locus_tag=NBT03_gp141;product=MHC class II antigen presentation inhibitor;protein_id=YP_010377144.1 +NC_063383.1 RefSeq gene 142778 143464 . + . ID=gene-NBT03_gp142;Dbxref=GeneID:72551558;Name=OPG164;gbkey=Gene;gene=OPG164;gene_biotype=protein_coding;locus_tag=NBT03_gp142;old_locus_tag=MPXV-M5312_HM12_Rivers-148 +NC_063383.1 RefSeq CDS 142778 143464 . + 0 ID=cds-YP_010377145.1;Parent=gene-NBT03_gp142;Dbxref=GenBank:YP_010377145.1,GeneID:72551558;Name=OPG164;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp148%3B IEV but not CEV envelope protein%3B plays critical role for actin tail formation%3B interacts with VAC A33R and A34R%3B IEV transmembrane phosphoprotein%3B similar to VACV-WR A38R and VACV-Cop A36R;gbkey=CDS;gene=OPG164;locus_tag=NBT03_gp142;product=IEV transmembrane phosphoprotein;protein_id=YP_010377145.1 +NC_063383.1 RefSeq gene 143516 144322 . + . ID=gene-NBT03_gp143;Dbxref=GeneID:72551559;Name=OPG165;gbkey=Gene;gene=OPG165;gene_biotype=protein_coding;locus_tag=NBT03_gp143;old_locus_tag=MPXV-M5312_HM12_Rivers-149 +NC_063383.1 RefSeq CDS 143516 144322 . + 0 ID=cds-YP_010377146.1;Parent=gene-NBT03_gp143;Dbxref=GenBank:YP_010377146.1,GeneID:72551559;Name=OPG165;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp149%3B Hypothetical protein%3B similar to VACV-WR A39R and VACV-Cop A37R;gbkey=CDS;gene=OPG165;locus_tag=NBT03_gp143;product=CPXV173 protein;protein_id=YP_010377146.1 +NC_063383.1 RefSeq gene 144398 144577 . + . ID=gene-NBT03_gp144;Dbxref=GeneID:72551560;Name=OPG166;gbkey=Gene;gene=OPG166;gene_biotype=protein_coding;locus_tag=NBT03_gp144 +NC_063383.1 RefSeq CDS 144398 144577 . + 0 ID=cds-YP_010415322.1;Parent=gene-NBT03_gp144;Dbxref=GenBank:YP_010415322.1,GeneID:72551560;Name=OPG166;Note=Hypothetical protein%3B according to YP_233043.1%2C this VACV-WR protein was purified by sucrose gradient centrifugation%3B similar to VACWR161 and VARGAR-A43R;gbkey=CDS;gene=OPG166;locus_tag=NBT03_gp144;product=hypothetical protein;protein_id=YP_010415322.1 +NC_063383.1 RefSeq gene 144574 145407 . - . ID=gene-NBT03_gp145;Dbxref=GeneID:72551561;Name=OPG167;gbkey=Gene;gene=OPG167;gene_biotype=protein_coding;locus_tag=NBT03_gp145;old_locus_tag=MPXV-M5312_HM12_Rivers-150 +NC_063383.1 RefSeq CDS 144574 145407 . - 0 ID=cds-YP_010377147.1;Parent=gene-NBT03_gp145;Dbxref=GenBank:YP_010377147.1,GeneID:72551561;Name=OPG167;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp150%3B integral membrane glycoprotein%3B immunoglobulin-like%3B regulation of the influx of extracellular Ca2+%3B CD47-like%3B similar to VACV-WR A40L and VACV-Cop A38L;gbkey=CDS;gene=OPG167;locus_tag=NBT03_gp145;product=CD47-like protein;protein_id=YP_010377147.1 +NC_063383.1 RefSeq sequence_feature 145423 145856 . + . ID=id-NC_063383.1:145423..145856;exon_number=OPG168;gbkey=misc_feature;number=OPG168 +NC_063383.1 RefSeq sequence_feature 145857 146039 . + . ID=id-NC_063383.1:145857..146039;exon_number=OPG169;gbkey=misc_feature;number=OPG169 +NC_063383.1 RefSeq gene 146113 146778 . - . ID=gene-NBT03_gp146;Dbxref=GeneID:72551562;Name=OPG170;gbkey=Gene;gene=OPG170;gene_biotype=protein_coding;locus_tag=NBT03_gp146;old_locus_tag=MPXV-M5312_HM12_Rivers-151 +NC_063383.1 RefSeq CDS 146113 146778 . - 0 ID=cds-YP_010377148.1;Parent=gene-NBT03_gp146;Dbxref=GenBank:YP_010377148.1,GeneID:72551562;Name=OPG170;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp151%3B secreted protein reducing infiltration of inflammatory cells into the infected area%3B Chemokine binding protein%3B similar to VACV-WR A41L and VACV-Cop A41L;gbkey=CDS;gene=OPG170;locus_tag=NBT03_gp146;product=Chemokine binding protein;protein_id=YP_010377148.1 +NC_063383.1 RefSeq gene 146988 147389 . + . ID=gene-NBT03_gp147;Dbxref=GeneID:72551563;Name=OPG171;gbkey=Gene;gene=OPG171;gene_biotype=protein_coding;locus_tag=NBT03_gp147;old_locus_tag=MPXV-M5312_HM12_Rivers-152 +NC_063383.1 RefSeq CDS 146988 147389 . + 0 ID=cds-YP_010377149.1;Parent=gene-NBT03_gp147;Dbxref=GenBank:YP_010377149.1,GeneID:72551563;Name=OPG171;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp152%3B Profilin-like protein%2C ATI-localized%3B similar to VACV-WR A42R and VACV-Cop A42R;gbkey=CDS;gene=OPG171;locus_tag=NBT03_gp147;product=Profilin domain protein;protein_id=YP_010377149.1 +NC_063383.1 RefSeq gene 147427 148017 . + . ID=gene-NBT03_gp148;Dbxref=GeneID:72551564;Name=OPG172;gbkey=Gene;gene=OPG172;gene_biotype=protein_coding;locus_tag=NBT03_gp148;old_locus_tag=MPXV-M5312_HM12_Rivers-153 +NC_063383.1 RefSeq CDS 147427 148017 . + 0 ID=cds-YP_010377150.1;Parent=gene-NBT03_gp148;Dbxref=GenBank:YP_010377150.1,GeneID:72551564;Name=OPG172;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp153%3B Type I membrane glycoprotein%3B similar to VACV-WR A43R and VACV-Cop A43R;gbkey=CDS;gene=OPG172;locus_tag=NBT03_gp148;product=Type-I membrane glycoprotein;protein_id=YP_010377150.1 +NC_063383.1 RefSeq gene 148037 148261 . + . ID=gene-NBT03_gp149;Dbxref=GeneID:72551565;Name=OPG173;gbkey=Gene;gene=OPG173;gene_biotype=protein_coding;locus_tag=NBT03_gp149;old_locus_tag=MPXV-M5312_HM12_Rivers-154 +NC_063383.1 RefSeq CDS 148037 148261 . + 0 ID=cds-YP_010377151.1;Parent=gene-NBT03_gp149;Dbxref=GenBank:YP_010377151.1,GeneID:72551565;Name=OPG173;Note=Old product: MPXVgp154%3B Hypothetical protein%3B similar to VACV-WR A44R and VACV-Cop A43.5R;gbkey=CDS;gene=OPG173;locus_tag=NBT03_gp149;product=MPXVgp154;protein_id=YP_010377151.1 +NC_063383.1 RefSeq gene 148355 149395 . - . ID=gene-NBT03_gp150;Dbxref=GeneID:72551566;Name=OPG174;gbkey=Gene;gene=OPG174;gene_biotype=protein_coding;locus_tag=NBT03_gp150;old_locus_tag=MPXV-M5312_HM12_Rivers-155 +NC_063383.1 RefSeq CDS 148355 149395 . - 0 ID=cds-YP_010377152.1;Parent=gene-NBT03_gp150;Dbxref=GenBank:YP_010377152.1,GeneID:72551566;Name=OPG174;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp155%3B 3-b-Hydroxy-delta5-steroid dehydrogenase%3B 3 beta-hydroxysteroid dehydrogenase/delta 5->4 isomerase%3B similar to VACV-WR A45L and VACV-Cop A44L;gbkey=CDS;gene=OPG174;locus_tag=NBT03_gp150;product=Hydroxysteroid dehydrogenase;protein_id=YP_010377152.1 +NC_063383.1 RefSeq gene 149442 149819 . + . ID=gene-NBT03_gp151;Dbxref=GeneID:72551567;Name=OPG175;gbkey=Gene;gene=OPG175;gene_biotype=protein_coding;locus_tag=NBT03_gp151;old_locus_tag=MPXV-M5312_HM12_Rivers-156 +NC_063383.1 RefSeq CDS 149442 149819 . + 0 ID=cds-YP_010377153.1;Parent=gene-NBT03_gp151;Dbxref=GenBank:YP_010377153.1,GeneID:72551567;Name=OPG175;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp156%3B virion core protein%3B Inactive Cu-Zn superoxide dismutase-like virion protein%3B similar to VACV-WR A46R and VACV-Cop A45R;gbkey=CDS;gene=OPG175;locus_tag=NBT03_gp151;product=Copper/zinc superoxide dismutase;protein_id=YP_010377153.1 +NC_063383.1 RefSeq gene 149809 150531 . + . ID=gene-NBT03_gp152;Dbxref=GeneID:72551568;Name=OPG176;gbkey=Gene;gene=OPG176;gene_biotype=protein_coding;locus_tag=NBT03_gp152;old_locus_tag=MPXV-M5312_HM12_Rivers-157 +NC_063383.1 RefSeq CDS 149809 150531 . + 0 ID=cds-YP_010377154.1;Parent=gene-NBT03_gp152;Dbxref=GenBank:YP_010377154.1,GeneID:72551568;Name=OPG176;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp157%3B IL-1/TLR signaling inhibitor%3B similar to VACV-WR A47R and VACV-Cop A46R;gbkey=CDS;gene=OPG176;locus_tag=NBT03_gp152;product=Bcl-2-like protein;protein_id=YP_010377154.1 +NC_063383.1 RefSeq sequence_feature 150684 151407 . - . ID=id-NC_063383.1:150684..151407;exon_number=OPG177;gbkey=misc_feature;number=OPG177 +NC_063383.1 RefSeq gene 151509 152123 . + . ID=gene-NBT03_gp153;Dbxref=GeneID:72551569;Name=OPG178;gbkey=Gene;gene=OPG178;gene_biotype=protein_coding;locus_tag=NBT03_gp153;old_locus_tag=MPXV-M5312_HM12_Rivers-158 +NC_063383.1 RefSeq CDS 151509 152123 . + 0 ID=cds-YP_010377155.1;Parent=gene-NBT03_gp153;Dbxref=GenBank:YP_010377155.1,GeneID:72551569;Name=OPG178;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp159%3B thymidylate kinase%3B start of ORF is missing approx. 37 AA compared to CPXVs%3B similar to VACV-WR A49R and VACV-Cop A48R;gbkey=CDS;gene=OPG178;locus_tag=NBT03_gp153;product=Thymidylate kinase;protein_id=YP_010377155.1 +NC_063383.1 RefSeq sequence_feature 152172 152660 . + . ID=id-NC_063383.1:152172..152660;exon_number=OPG179;gbkey=misc_feature;number=OPG179 +NC_063383.1 RefSeq gene 152692 154371 . + . ID=gene-NBT03_gp154;Dbxref=GeneID:72551570;Name=OPG180;gbkey=Gene;gene=OPG180;gene_biotype=protein_coding;locus_tag=NBT03_gp154;old_locus_tag=MPXV-M5312_HM12_Rivers-159 +NC_063383.1 RefSeq CDS 152692 154371 . + 0 ID=cds-YP_010377156.1;Parent=gene-NBT03_gp154;Dbxref=GenBank:YP_010377156.1,GeneID:72551570;Name=OPG180;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp160%3B ATP-dependent DNA ligase%3B similar to VACV-WR A50R and VACV-Cop A50R;gbkey=CDS;gene=OPG180;locus_tag=NBT03_gp154;product=DNA ligase (2);protein_id=YP_010377156.1 +NC_063383.1 RefSeq gene 154412 155416 . + . ID=gene-NBT03_gp155;Dbxref=GeneID:72551571;Name=OPG181;gbkey=Gene;gene=OPG181;gene_biotype=protein_coding;locus_tag=NBT03_gp155;old_locus_tag=MPXV-M5312_HM12_Rivers-160 +NC_063383.1 RefSeq CDS 154412 155416 . + 0 ID=cds-YP_010377157.1;Parent=gene-NBT03_gp155;Dbxref=GenBank:YP_010377157.1,GeneID:72551571;Name=OPG181;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp161%3B Hypothetical protein%3B similar to VACV-WR A51R and VACV-Cop A51R;gbkey=CDS;gene=OPG181;locus_tag=NBT03_gp155;product=M137R;protein_id=YP_010377157.1 +NC_063383.1 RefSeq sequence_feature 155485 156037 . + . ID=id-NC_063383.1:155485..156037;exon_number=OPG182;gbkey=misc_feature;number=OPG182 +NC_063383.1 RefSeq sequence_feature 156355 156916 . + . ID=id-NC_063383.1:156355..156916;exon_number=OPG183;gbkey=misc_feature;number=OPG183 +NC_063383.1 RefSeq sequence_feature 157176 158867 . + . ID=id-NC_063383.1:157176..158867;exon_number=OPG184;gbkey=misc_feature;number=OPG184 +NC_063383.1 RefSeq gene 158917 159858 . + . ID=gene-NBT03_gp156;Dbxref=GeneID:72551572;Name=OPG185;gbkey=Gene;gene=OPG185;gene_biotype=protein_coding;locus_tag=NBT03_gp156;old_locus_tag=MPXV-M5312_HM12_Rivers-162 +NC_063383.1 RefSeq CDS 158917 159858 . + 0 ID=cds-YP_010377158.1;Parent=gene-NBT03_gp156;Dbxref=GenBank:YP_010377158.1,GeneID:72551572;Name=OPG185;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp163%3B EEV envelope and cell membrane glycoprotein hemagglutinin%3B inhibition of the ability of infected cells to fuse%3B interacts with VAC F13L%3B similar to VACV-WR B2R and VACV-Cop A56R;gbkey=CDS;gene=OPG185;locus_tag=NBT03_gp156;product=Hemagglutinin;protein_id=YP_010377158.1 +NC_063383.1 RefSeq sequence_feature 159876 160470 . + . ID=id-NC_063383.1:159876..160470;exon_number=OPG186;gbkey=misc_feature;number=OPG186 +NC_063383.1 RefSeq gene 160622 161533 . + . ID=gene-NBT03_gp157;Dbxref=GeneID:72551573;Name=OPG187;gbkey=Gene;gene=OPG187;gene_biotype=protein_coding;locus_tag=NBT03_gp157;old_locus_tag=MPXV-M5312_HM12_Rivers-163 +NC_063383.1 RefSeq CDS 160622 161533 . + 0 ID=cds-YP_010377159.1;Parent=gene-NBT03_gp157;Dbxref=GenBank:YP_010377159.1,GeneID:72551573;Name=OPG187;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp164%3B serine%3B Ser/Thr Kinase%3B similar to VACV-WR B3R and VACV-Cop B1R;gbkey=CDS;gene=OPG187;locus_tag=NBT03_gp157;product=Ser/thr kinase;protein_id=YP_010377159.1 +NC_063383.1 RefSeq gene 161596 163107 . + . ID=gene-NBT03_gp158;Dbxref=GeneID:72551574;Name=OPG188;gbkey=Gene;gene=OPG188;gene_biotype=protein_coding;locus_tag=NBT03_gp158;old_locus_tag=MPXV-M5312_HM12_Rivers-164 +NC_063383.1 RefSeq CDS 161596 163107 . + 0 ID=cds-YP_010377160.1;Parent=gene-NBT03_gp158;Dbxref=GenBank:YP_010377160.1,GeneID:72551574;Name=OPG188;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp165%3B schlafen-like%3B similar to VACV-WR B4R and VACV-Cop B2R;gbkey=CDS;gene=OPG188;locus_tag=NBT03_gp158;product=Schlafen (1);protein_id=YP_010377160.1 +NC_063383.1 RefSeq gene 163333 165018 . + . ID=gene-NBT03_gp159;Dbxref=GeneID:72551575;Name=OPG189;gbkey=Gene;gene=OPG189;gene_biotype=protein_coding;locus_tag=NBT03_gp159;old_locus_tag=MPXV-M5312_HM12_Rivers-165 +NC_063383.1 RefSeq CDS 163333 165018 . + 0 ID=cds-YP_010377161.1;Parent=gene-NBT03_gp159;Dbxref=GenBank:YP_010377161.1,GeneID:72551575;Name=OPG189;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp166%3B ankyrin-like%3B similar to VACV-WR B5R and VACV-Cop B4R;gbkey=CDS;gene=OPG189;locus_tag=NBT03_gp159;product=Ankyrin repeat protein (25);protein_id=YP_010377161.1 +NC_063383.1 RefSeq gene 165122 166075 . + . ID=gene-NBT03_gp160;Dbxref=GeneID:72551576;Name=OPG190;gbkey=Gene;gene=OPG190;gene_biotype=protein_coding;locus_tag=NBT03_gp160;old_locus_tag=MPXV-M5312_HM12_Rivers-166 +NC_063383.1 RefSeq CDS 165122 166075 . + 0 ID=cds-YP_010377162.1;Parent=gene-NBT03_gp160;Dbxref=GenBank:YP_010377162.1,GeneID:72551576;Name=OPG190;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp167%3B palmitated 42 kDa glycoprotein located both on the membranes of infected cells and on EEV envelope%3B complement control protein-like%3B EEV type-1 membrane glycoprotein%2C protective antigen%3B similar to VACV-WR B6R and VACV-Cop B5R;gbkey=CDS;gene=OPG190;locus_tag=NBT03_gp160;product=EEV type-I membrane glycoprotein;protein_id=YP_010377162.1 +NC_063383.1 RefSeq gene 166161 166667 . + . ID=gene-NBT03_gp161;Dbxref=GeneID:72551577;Name=OPG191;gbkey=Gene;gene=OPG191;gene_biotype=protein_coding;locus_tag=NBT03_gp161;old_locus_tag=MPXV-M5312_HM12_Rivers-167 +NC_063383.1 RefSeq CDS 166161 166667 . + 0 ID=cds-YP_010377163.1;Parent=gene-NBT03_gp161;Dbxref=GenBank:YP_010377163.1,GeneID:72551577;Name=OPG191;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp168%3B Ankyrin-like protein%3B similar to VACV-WR B7R and VACV-Cop B6R;gbkey=CDS;gene=OPG191;locus_tag=NBT03_gp161;product=Ankyrin-like protein (46);protein_id=YP_010377163.1 +NC_063383.1 RefSeq gene 166731 167279 . + . ID=gene-NBT03_gp162;Dbxref=GeneID:72551578;Name=OPG192;gbkey=Gene;gene=OPG192;gene_biotype=protein_coding;locus_tag=NBT03_gp162;old_locus_tag=MPXV-M5312_HM12_Rivers-168 +NC_063383.1 RefSeq CDS 166731 167279 . + 0 ID=cds-YP_010377164.1;Parent=gene-NBT03_gp162;Dbxref=GenBank:YP_010377164.1,GeneID:72551578;Name=OPG192;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp169%3B Virulence%2C ER resident%3B similar to VACV-WR B8R and VACV-Cop B7R;gbkey=CDS;gene=OPG192;locus_tag=NBT03_gp162;product=Virulence protein;protein_id=YP_010377164.1 +NC_063383.1 RefSeq gene 167334 168137 . + . ID=gene-NBT03_gp163;Dbxref=GeneID:72551579;Name=OPG193;gbkey=Gene;gene=OPG193;gene_biotype=protein_coding;locus_tag=NBT03_gp163;old_locus_tag=MPXV-M5312_HM12_Rivers-169 +NC_063383.1 RefSeq CDS 167334 168137 . + 0 ID=cds-YP_010377165.1;Parent=gene-NBT03_gp163;Dbxref=GenBank:YP_010377165.1,GeneID:72551579;Name=OPG193;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp170%3B secreted IFN-g binding protein%3B Soluble IFN-g receptor-like protein%3B similar to VACV-WR B9R and VACV-Cop B8R;gbkey=CDS;gene=OPG193;locus_tag=NBT03_gp163;product=Soluble interferon-gamma receptor-like protein;protein_id=YP_010377165.1 +NC_063383.1 RefSeq gene 168230 168895 . + . ID=gene-NBT03_gp164;Dbxref=GeneID:72551580;Name=OPG195;gbkey=Gene;gene=OPG195;gene_biotype=protein_coding;locus_tag=NBT03_gp164;old_locus_tag=MPXV-M5312_HM12_Rivers-170 +NC_063383.1 RefSeq CDS 168230 168895 . + 0 ID=cds-YP_010377166.1;Parent=gene-NBT03_gp164;Dbxref=GenBank:YP_010377166.1,GeneID:72551580;Name=OPG195;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp171%3B shope fibroma virus T4 protein-like%3B ER-localized apoptosis regulator%3B similar to VACV-WR B10R and VACV-Cop B9R;gbkey=CDS;gene=OPG195;locus_tag=NBT03_gp164;product=Intracellular viral protein;protein_id=YP_010377166.1 +NC_063383.1 RefSeq sequence_feature 169001 169642 . + . ID=id-NC_063383.1:169001..169642;exon_number=OPG196;gbkey=misc_feature;number=OPG196 +NC_063383.1 RefSeq gene 169670 169972 . + . ID=gene-NBT03_gp165;Dbxref=GeneID:72551581;Name=OPG197;gbkey=Gene;gene=OPG197;gene_biotype=protein_coding;locus_tag=NBT03_gp165;old_locus_tag=MPXV-M5312_HM12_Rivers-171 +NC_063383.1 RefSeq CDS 169670 169972 . + 0 ID=cds-YP_010377167.1;Parent=gene-NBT03_gp165;Dbxref=GenBank:YP_010377167.1,GeneID:72551581;Name=OPG197;Note=Taxonomic breadth: chordopoxvirinae%3B Hypothetical protein%3B similar to VACV-Cop-B11R;gbkey=CDS;gene=OPG197;locus_tag=NBT03_gp165;product=CPXV205 protein;protein_id=YP_010377167.1 +NC_063383.1 RefSeq gene 170038 170886 . + . ID=gene-NBT03_gp166;Dbxref=GeneID:72551582;Name=OPG198;gbkey=Gene;gene=OPG198;gene_biotype=protein_coding;locus_tag=NBT03_gp166;old_locus_tag=MPXV-M5312_HM12_Rivers-172 +NC_063383.1 RefSeq CDS 170038 170886 . + 0 ID=cds-YP_010377168.1;Parent=gene-NBT03_gp166;Dbxref=GenBank:YP_010377168.1,GeneID:72551582;Name=OPG198;Note=Taxonomic breadth: poxviridae%3B protein kinase-like%3B similar to VACV-WR B11R and VACV-Cop B12R;gbkey=CDS;gene=OPG198;locus_tag=NBT03_gp166;product=Ser/thr kinase;protein_id=YP_010377168.1 +NC_063383.1 RefSeq gene 170988 172022 . + . ID=gene-NBT03_gp167;Dbxref=GeneID:72551583;Name=OPG199;gbkey=Gene;gene=OPG199;gene_biotype=protein_coding;locus_tag=NBT03_gp167;old_locus_tag=MPXV-M5312_HM12_Rivers-173 +NC_063383.1 RefSeq CDS 170988 172022 . + 0 ID=cds-YP_010377169.1;Parent=gene-NBT03_gp167;Dbxref=GenBank:YP_010377169.1,GeneID:72551583;Name=OPG199;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp173%3B serine protease inhibitor-like%2C SPI-2%3B inhibition of the IL-1b converting enzyme%3B apoptosis inhibition%3B Serpin 1%2C2%2C3%3B similar to VACV-WR B12R and VACV-Cop K2L;gbkey=CDS;gene=OPG199;locus_tag=NBT03_gp167;product=Serpin;protein_id=YP_010377169.1 +NC_063383.1 RefSeq gene 172150 172599 . + . ID=gene-NBT03_gp168;Dbxref=GeneID:72551584;Name=OPG200;gbkey=Gene;gene=OPG200;gene_biotype=protein_coding;locus_tag=NBT03_gp168;old_locus_tag=MPXV-M5312_HM12_Rivers-174 +NC_063383.1 RefSeq CDS 172150 172599 . + 0 ID=cds-YP_010377170.1;Parent=gene-NBT03_gp168;Dbxref=GenBank:YP_010377170.1,GeneID:72551584;Name=OPG200;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp174%3B Hypothetical protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR B13R and VACV-Cop C16L and B15R;gbkey=CDS;gene=OPG200;locus_tag=NBT03_gp168;product=Bcl-2-like protein;protein_id=YP_010377170.1 +NC_063383.1 RefSeq sequence_feature 172685 173697 . + . ID=id-NC_063383.1:172685..173697;exon_number=OPG201;gbkey=misc_feature;number=OPG201 +NC_063383.1 RefSeq sequence_feature 173744 174187 . - . ID=id-NC_063383.1:173744..174187;exon_number=OPG202;gbkey=misc_feature;number=OPG202 +NC_063383.1 RefSeq sequence_feature 174328 174456 . + . ID=id-NC_063383.1:174328..174456;exon_number=OPG203;gbkey=misc_feature;number=OPG203 +NC_063383.1 RefSeq gene 174532 175587 . + . ID=gene-NBT03_gp169;Dbxref=GeneID:72551585;Name=OPG204;gbkey=Gene;gene=OPG204;gene_biotype=protein_coding;locus_tag=NBT03_gp169;old_locus_tag=MPXV-M5312_HM12_Rivers-177 +NC_063383.1 RefSeq CDS 174532 175587 . + 0 ID=cds-YP_010377172.1;Parent=gene-NBT03_gp169;Dbxref=GenBank:YP_010377172.1,GeneID:72551585;Name=OPG204;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp177%3B cell surface antigen and secreted IFN-a%3B IFN-alpha/beta receptor glycoprotein%3B similar to VACV-WR B16R and VACV-Cop B19R;gbkey=CDS;gene=OPG204;locus_tag=NBT03_gp169;product=IFN-alpha/beta-receptor-like secreted glycoprotein;protein_id=YP_010377172.1 +NC_063383.1 RefSeq gene 175656 178019 . + . ID=gene-NBT03_gp170;Dbxref=GeneID:72551586;Name=OPG205;gbkey=Gene;gene=OPG205;gene_biotype=protein_coding;locus_tag=NBT03_gp170;old_locus_tag=MPXV-M5312_HM12_Rivers-178 +NC_063383.1 RefSeq CDS 175656 178019 . + 0 ID=cds-YP_010377173.1;Parent=gene-NBT03_gp170;Dbxref=GenBank:YP_010377173.1,GeneID:72551586;Name=OPG205;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp178%3B ankyrin-like%3B similar to VACV-WR B17R and VACV-Cop B20R;gbkey=CDS;gene=OPG205;locus_tag=NBT03_gp170;product=Ankyrin repeat protein (44);protein_id=YP_010377173.1 +NC_063383.1 RefSeq sequence_feature 178118 178916 . + . ID=id-NC_063383.1:178118..178916;exon_number=OPG206;gbkey=misc_feature;number=OPG206 +NC_063383.1 RefSeq gene 179266 180339 . + . ID=gene-NBT03_gp171;Dbxref=GeneID:72551587;Name=OPG208;gbkey=Gene;gene=OPG208;gene_biotype=protein_coding;locus_tag=NBT03_gp171;old_locus_tag=MPXV-M5312_HM12_Rivers-180 +NC_063383.1 RefSeq CDS 179266 180339 . + 0 ID=cds-YP_010377174.1;Parent=gene-NBT03_gp171;Dbxref=GenBank:YP_010377174.1,GeneID:72551587;Name=OPG208;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp180%3B serine protease inhibitor-like%2C SPI-1%3B apoptosis inhibition%3B Serpin 1%2C2%2C3%3B Actual start may be at position 179%2C074%3B annotated start of ORF is missing approx. 17 AA compared to CPXVs%3B similar to VACV-WR B19R and VACV-Cop K2L;gbkey=CDS;gene=OPG208;locus_tag=NBT03_gp171;product=Serpin;protein_id=YP_010377174.1 +NC_063383.1 RefSeq gene 180518 181090 . + . ID=gene-NBT03_gp172;Dbxref=GeneID:72551588;Name=OPG209;gbkey=Gene;gene=OPG209;gene_biotype=protein_coding;locus_tag=NBT03_gp172;old_locus_tag=MPXV-M5312_HM12_Rivers-181 +NC_063383.1 RefSeq CDS 180518 181090 . + 0 ID=cds-YP_010377175.1;Parent=gene-NBT03_gp172;Dbxref=GenBank:YP_010377175.1,GeneID:72551588;Name=OPG209;Note=Old product: MPXVgp181%3B Hypothetical protein%3B similar to VACV-WR B20R and VACV-Cop C14L;gbkey=CDS;gene=OPG209;locus_tag=NBT03_gp172;product=Virulence protein;protein_id=YP_010377175.1 +NC_063383.1 RefSeq gene 181356 186998 . + . ID=gene-NBT03_gp173;Dbxref=GeneID:72551589;Name=OPG210;gbkey=Gene;gene=OPG210;gene_biotype=protein_coding;locus_tag=NBT03_gp173;old_locus_tag=MPXV-M5312_HM12_Rivers-182 +NC_063383.1 RefSeq CDS 181356 186998 . + 0 ID=cds-YP_010377176.1;Parent=gene-NBT03_gp173;Dbxref=GenBank:YP_010377176.1,GeneID:72551589;Name=OPG210;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp182%3B Surface glycoprotein%3B putative membrane-associated glycoprotein%3B cadherin-like domain%3B similar to VACV-WR B21R;gbkey=CDS;gene=OPG210;locus_tag=NBT03_gp173;product=B22R family protein;protein_id=YP_010377176.1 +NC_063383.1 RefSeq sequence_feature 187317 187743 . + . ID=id-NC_063383.1:187317..187743;exon_number=OPG212;gbkey=misc_feature;number=OPG212 +NC_063383.1 RefSeq sequence_feature 187822 188298 . + . ID=id-NC_063383.1:187822..188298;exon_number=OPG213;gbkey=misc_feature;number=OPG213 +NC_063383.1 RefSeq sequence_feature 188458 188963 . + . ID=id-NC_063383.1:188458..188963;exon_number=OPG214;gbkey=misc_feature;number=OPG214 +NC_063383.1 RefSeq gene 189199 189660 . + . ID=gene-NBT03_gp174;Dbxref=GeneID:72551590;Name=OPG005;gbkey=Gene;gene=OPG005;gene_biotype=protein_coding;locus_tag=NBT03_gp174;old_locus_tag=MPXV-M5312_HM12_Rivers-184 +NC_063383.1 RefSeq CDS 189199 189660 . + 0 ID=cds-YP_010377177.1;Parent=gene-NBT03_gp174;Dbxref=GenBank:YP_010377177.1,GeneID:72551590;Name=OPG005;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp185%3B VAC B15R-like%3B Hypothetical protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR N1R and VACV-Cop C16L and B22R;gbkey=CDS;gene=OPG005;locus_tag=NBT03_gp174;product=Bcl-2-like protein;protein_id=YP_010377177.1 +NC_063383.1 RefSeq gene 190410 190940 . + . ID=gene-NBT03_gp175;Dbxref=GeneID:72551591;Name=OPG016;gbkey=Gene;gene=OPG016;gene_biotype=protein_coding;locus_tag=NBT03_gp175;old_locus_tag=MPXV-M5312_HM12_Rivers-186 +NC_063383.1 RefSeq CDS 190410 190940 . + 0 ID=cds-YP_010377184.1;Parent=gene-NBT03_gp175;Dbxref=GenBank:YP_010377184.1,GeneID:72551591;Name=OPG016;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp187%3B similar to VACV-WR N3R;gbkey=CDS;gene=OPG016;locus_tag=NBT03_gp175;product=Brix domain protein;protein_id=YP_010377184.1 +NC_063383.1 RefSeq long_terminal_repeat 190788 197209 . + . ID=id-NC_063383.1:190788..197209;gbkey=repeat_region;rpt_type=long_terminal_repeat +NC_063383.1 RefSeq gene 191054 192367 . + . ID=gene-NBT03_gp176;Dbxref=GeneID:72551592;Name=OPG015_dup;gbkey=Gene;gene=OPG015_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp176;old_locus_tag=MPXV-M5312_HM12_Rivers-187 +NC_063383.1 RefSeq CDS 191054 192367 . + 0 ID=cds-YP_010377179.1;Parent=gene-NBT03_gp176;Dbxref=GenBank:YP_010377179.1,GeneID:72551592;Name=OPG015_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp188%3B ankyrin-like%3B Ankyrin (CPXV-017)%3B similar to VACV-WR N4R;gbkey=CDS;gene=OPG015_dup;locus_tag=NBT03_gp176;product=Ankyrin repeat protein (39);protein_id=YP_010377179.1 +NC_063383.1 RefSeq gene 192603 194369 . + . ID=gene-NBT03_gp177;Dbxref=GeneID:72551593;Name=OPG003_dup;gbkey=Gene;gene=OPG003_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp177;old_locus_tag=MPXV-M5312_HM12_Rivers-188 +NC_063383.1 RefSeq CDS 192603 194369 . + 0 ID=cds-YP_010377180.1;Parent=gene-NBT03_gp177;Dbxref=GenBank:YP_010377180.1,GeneID:72551593;Name=OPG003_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp189%3B ankyrin-like%3B similar to VACV-WR J1R and VACV-Cop C19L;gbkey=CDS;gene=OPG003_dup;locus_tag=NBT03_gp177;product=Ankyrin repeat protein (25);protein_id=YP_010377180.1 +NC_063383.1 RefSeq gene 194459 195508 . + . ID=gene-NBT03_gp178;Dbxref=GeneID:72551594;Name=OPG002_dup;gbkey=Gene;gene=OPG002_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp178;old_locus_tag=MPXV-M5312_HM12_Rivers-189 +NC_063383.1 RefSeq CDS 194459 195508 . + 0 ID=cds-YP_010377181.1;Parent=gene-NBT03_gp178;Dbxref=GenBank:YP_010377181.1,GeneID:72551594;Name=OPG002_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp190%3B secreted TNF binding protein%3B TNF receptor (CrmB)%3B similar to VACV-WR J2R and VACV-Cop C22L;gbkey=CDS;gene=OPG002_dup;locus_tag=NBT03_gp178;product=Crm-B secreted TNF-alpha-receptor-like protein;protein_id=YP_010377181.1 +NC_063383.1 RefSeq gene 195635 196375 . + . ID=gene-NBT03_gp179;Dbxref=GeneID:72551595;Name=OPG001_dup;gbkey=Gene;gene=OPG001_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp179;old_locus_tag=MPXV-M5312_HM12_Rivers-190 +NC_063383.1 RefSeq CDS 195635 196375 . + 0 ID=cds-YP_010377182.1;Parent=gene-NBT03_gp179;Dbxref=GenBank:YP_010377182.1,GeneID:72551595;Name=OPG001_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp191%3B Chemokine binding protein (Cop-C23L)%3B most abundant secreted protein%3B CC-chemokine binding protein%3B similar to VACV-WR J3R and VACV-Cop C23L and B29R;gbkey=CDS;gene=OPG001_dup;locus_tag=NBT03_gp179;product=Chemokine binding protein;protein_id=YP_010377182.1 diff --git a/data/nextstrain/mpox/lineage-b.1/pathogen.json b/data/nextstrain/mpox/lineage-b.1/pathogen.json new file mode 100644 index 00000000..6b453c98 --- /dev/null +++ b/data/nextstrain/mpox/lineage-b.1/pathogen.json @@ -0,0 +1,284 @@ +{ + "alignmentParams": { + "excessBandwidth": 40, + "terminalBandwidth": 200, + "allowedMismatches": 5, + "windowSize": 30, + "minSeedCover": 0.1, + "gapAlignmentSide": "left" + }, + "attributes": { + "name": "Mpox virus (Lineage B.1)", + "reference accession": "NC_063383.1 (with B.1 SNPs)", + "reference name": "MPXV-M5312_HM12_Rivers with B.1 SNPs" + }, + "compatibility": { + "cli": "3.0.0-alpha.0", + "web": "3.0.0-alpha.0" + }, + "deprecated": false, + "enabled": true, + "experimental": false, + "files": { + "changelog": "CHANGELOG.md", + "examples": "sequences.fasta", + "genomeAnnotation": "genome_annotation.gff3", + "pathogenJson": "pathogen.json", + "readme": "README.md", + "reference": "reference.fasta", + "treeJson": "tree.json" + }, + "mutLabels": { + "nucMutLabelMap": { + "100261A": [ + "rev" + ], + "119296C": [ + "rev" + ], + "121320C": [ + "rev" + ], + "124130G": [ + "rev" + ], + "124674G": [ + "rev" + ], + "125249G": [ + "rev" + ], + "1262G": [ + "rev" + ], + "128698C": [ + "rev" + ], + "14000G": [ + "rev" + ], + "148412G": [ + "rev" + ], + "150469C": [ + "rev" + ], + "151461A": [ + "rev" + ], + "15428G": [ + "rev" + ], + "154408T": [ + "rev" + ], + "155795G": [ + "rev" + ], + "162243G": [ + "rev" + ], + "162331C": [ + "rev" + ], + "164832C": [ + "rev" + ], + "168120C": [ + "rev" + ], + "170262G": [ + "rev" + ], + "178133G": [ + "rev" + ], + "181980G": [ + "rev" + ], + "183519C": [ + "rev" + ], + "186578G": [ + "rev" + ], + "187428C": [ + "rev" + ], + "18769A": [ + "rev" + ], + "193392G": [ + "rev" + ], + "193688C": [ + "rev" + ], + "194099C": [ + "rev" + ], + "194619C": [ + "rev" + ], + "195948C": [ + "rev" + ], + "21723G": [ + "rev" + ], + "23564C": [ + "rev" + ], + "25661G": [ + "rev" + ], + "2591G": [ + "rev" + ], + "28175T": [ + "rev" + ], + "30367G": [ + "rev" + ], + "31053G": [ + "rev" + ], + "3111G": [ + "rev" + ], + "34459G": [ + "rev" + ], + "3522G": [ + "rev" + ], + "37202G": [ + "rev" + ], + "3818C": [ + "rev" + ], + "38360G": [ + "rev" + ], + "38662C": [ + "rev" + ], + "39119C": [ + "rev" + ], + "39139C": [ + "rev" + ], + "52885G": [ + "rev" + ], + "54117G": [ + "rev" + ], + "54635G": [ + "rev" + ], + "64297G": [ + "rev" + ], + "72362C": [ + "rev" + ], + "73066C": [ + "rev" + ], + "73239G": [ + "rev" + ], + "74205G": [ + "rev" + ], + "77383G": [ + "rev" + ], + "7771C": [ + "rev" + ], + "81275G": [ + "rev" + ], + "81977A": [ + "rev" + ], + "82373C": [ + "rev" + ], + "82451G": [ + "rev" + ], + "83326C": [ + "rev" + ], + "84587C": [ + "rev" + ], + "87230G": [ + "rev" + ], + "87297G": [ + "rev" + ], + "91728G": [ + "rev" + ], + "95034G": [ + "rev" + ] + } + }, + "official": true, + "qc": { + "frameShifts": { + "enabled": true, + "scoreWeight": 20 + }, + "missingData": { + "enabled": true, + "missingDataThreshold": 20000, + "scoreBias": 1000 + }, + "mixedSites": { + "enabled": true, + "mixedSitesThreshold": 40 + }, + "privateMutations": { + "cutoff": 50, + "enabled": true, + "typical": 5, + "weightLabeledSubstitutions": 6, + "weightReversionSubstitutions": 6, + "weightUnlabeledSubstitutions": 1 + }, + "snpClusters": { + "clusterCutOff": 5, + "enabled": true, + "scoreWeight": 20, + "windowSize": 100 + }, + "stopCodons": { + "enabled": true, + "ignoredStopCodons": [ + { + "codon": 187, + "geneName": "OPG015_dup" + }, + { + "codon": 187, + "geneName": "OPG015" + } + ], + "scoreWeight": 40 + } + }, + "schemaVersion": "3.0.0", + "version": { + "tag": "unreleased" + } +} diff --git a/data/nextstrain/mpox/lineage-b.1/reference.fasta b/data/nextstrain/mpox/lineage-b.1/reference.fasta new file mode 100644 index 00000000..a69fa925 --- /dev/null +++ b/data/nextstrain/mpox/lineage-b.1/reference.fasta @@ -0,0 +1,2 @@ +>ref_in_coord MPXV_USA_2022_MA001 sequence in NC_063383 coordinates +ATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTTGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGAGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGAGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAAT diff --git a/data/nextstrain/mpx/hmpxv/NC_063383.1/sequences.fasta b/data/nextstrain/mpox/lineage-b.1/sequences.fasta similarity index 100% rename from data/nextstrain/mpx/hmpxv/NC_063383.1/sequences.fasta rename to data/nextstrain/mpox/lineage-b.1/sequences.fasta diff --git a/data/nextstrain/mpox/lineage-b.1/tree.json b/data/nextstrain/mpox/lineage-b.1/tree.json new file mode 100644 index 00000000..a4ec4c9f --- /dev/null +++ b/data/nextstrain/mpox/lineage-b.1/tree.json @@ -0,0 +1 @@ +{"version":"v2","meta":{"title":"Nextclade reference tree for Mpox virus (Lineage B.1)","updated":"2023-11-21","build_url":"https://github.com/nextstrain/mpox/nextclade","data_provenance":[{"name":"GenBank","url":"https://www.ncbi.nlm.nih.gov/genbank/"}],"maintainers":[{"name":"Cornelius Roemer","url":"https://neherlab.org"},{"name":"Richard Neher","url":"https://neherlab.org"},{"name":"Nextstrain team","url":"https://nextstrain.org"}],"display_defaults":{"color_by":"lineage","map_triplicate":false,"distance_measure":"div","tip_label":"strain_display","transmission_lines":false},"genome_annotations":{"OPG001":{"end":1575,"seqid":"resources/genome_annotation.gff3","start":835,"strand":"-","type":"gene"},"OPG001_dup":{"end":196375,"seqid":"resources/genome_annotation.gff3","start":195635,"strand":"+","type":"gene"},"OPG002":{"end":2751,"seqid":"resources/genome_annotation.gff3","start":1702,"strand":"-","type":"gene"},"OPG002_dup":{"end":195508,"seqid":"resources/genome_annotation.gff3","start":194459,"strand":"+","type":"gene"},"OPG003":{"end":4607,"seqid":"resources/genome_annotation.gff3","start":2841,"strand":"-","type":"gene"},"OPG003_dup":{"end":194369,"seqid":"resources/genome_annotation.gff3","start":192603,"strand":"+","type":"gene"},"OPG005":{"end":189660,"seqid":"resources/genome_annotation.gff3","start":189199,"strand":"+","type":"gene"},"OPG015":{"end":6156,"seqid":"resources/genome_annotation.gff3","start":4843,"strand":"-","type":"gene"},"OPG015_dup":{"end":192367,"seqid":"resources/genome_annotation.gff3","start":191054,"strand":"+","type":"gene"},"OPG016":{"end":190940,"seqid":"resources/genome_annotation.gff3","start":190410,"strand":"+","type":"gene"},"OPG019":{"end":8008,"seqid":"resources/genome_annotation.gff3","start":7580,"strand":"+","type":"gene"},"OPG021":{"end":10315,"seqid":"resources/genome_annotation.gff3","start":9587,"strand":"+","type":"gene"},"OPG022":{"end":10858,"seqid":"resources/genome_annotation.gff3","start":10478,"strand":"-","type":"gene"},"OPG023":{"end":12900,"seqid":"resources/genome_annotation.gff3","start":10918,"strand":"-","type":"gene"},"OPG024":{"end":13228,"seqid":"resources/genome_annotation.gff3","start":13034,"strand":"-","type":"gene"},"OPG025":{"end":15267,"seqid":"resources/genome_annotation.gff3","start":13375,"strand":"-","type":"gene"},"OPG027":{"end":16377,"seqid":"resources/genome_annotation.gff3","start":15925,"strand":"-","type":"gene"},"OPG029":{"end":17069,"seqid":"resources/genome_annotation.gff3","start":16602,"strand":"-","type":"gene"},"OPG030":{"end":17833,"seqid":"resources/genome_annotation.gff3","start":17213,"strand":"-","type":"gene"},"OPG031":{"end":18828,"seqid":"resources/genome_annotation.gff3","start":17878,"strand":"-","type":"gene"},"OPG034":{"end":20005,"seqid":"resources/genome_annotation.gff3","start":19361,"strand":"-","type":"gene"},"OPG035":{"end":20404,"seqid":"resources/genome_annotation.gff3","start":20051,"strand":"-","type":"gene"},"OPG036":{"end":21064,"seqid":"resources/genome_annotation.gff3","start":20531,"strand":"-","type":"gene"},"OPG037":{"end":22433,"seqid":"resources/genome_annotation.gff3","start":21105,"strand":"-","type":"gene"},"OPG038":{"end":23159,"seqid":"resources/genome_annotation.gff3","start":22497,"strand":"-","type":"gene"},"OPG039":{"end":24118,"seqid":"resources/genome_annotation.gff3","start":23264,"strand":"-","type":"gene"},"OPG040":{"end":25478,"seqid":"resources/genome_annotation.gff3","start":24351,"strand":"-","type":"gene"},"OPG042":{"end":27097,"seqid":"resources/genome_annotation.gff3","start":25823,"strand":"-","type":"gene"},"OPG043":{"end":27955,"seqid":"resources/genome_annotation.gff3","start":27125,"strand":"-","type":"gene"},"OPG044":{"end":28540,"seqid":"resources/genome_annotation.gff3","start":28091,"strand":"+","type":"gene"},"OPG045":{"end":29262,"seqid":"resources/genome_annotation.gff3","start":28603,"strand":"-","type":"gene"},"OPG046":{"end":29729,"seqid":"resources/genome_annotation.gff3","start":29274,"strand":"-","type":"gene"},"OPG047":{"end":31194,"seqid":"resources/genome_annotation.gff3","start":29746,"strand":"-","type":"gene"},"OPG048":{"end":32164,"seqid":"resources/genome_annotation.gff3","start":31205,"strand":"-","type":"gene"},"OPG049":{"end":33151,"seqid":"resources/genome_annotation.gff3","start":32195,"strand":"-","type":"gene"},"OPG050":{"end":33408,"seqid":"resources/genome_annotation.gff3","start":33181,"strand":"-","type":"gene"},"OPG051":{"end":33649,"seqid":"resources/genome_annotation.gff3","start":33425,"strand":"-","type":"gene"},"OPG052":{"end":33995,"seqid":"resources/genome_annotation.gff3","start":33801,"strand":"-","type":"gene"},"OPG053":{"end":34690,"seqid":"resources/genome_annotation.gff3","start":34052,"strand":"-","type":"gene"},"OPG054":{"end":35996,"seqid":"resources/genome_annotation.gff3","start":34677,"strand":"-","type":"gene"},"OPG055":{"end":37083,"seqid":"resources/genome_annotation.gff3","start":36019,"strand":"-","type":"gene"},"OPG056":{"end":39034,"seqid":"resources/genome_annotation.gff3","start":37127,"strand":"-","type":"gene"},"OPG057":{"end":40195,"seqid":"resources/genome_annotation.gff3","start":39077,"strand":"-","type":"gene"},"OPG058":{"end":40434,"seqid":"resources/genome_annotation.gff3","start":40213,"strand":"-","type":"gene"},"OPG059":{"end":40633,"seqid":"resources/genome_annotation.gff3","start":40484,"strand":"-","type":"gene"},"OPG060":{"end":41182,"seqid":"resources/genome_annotation.gff3","start":40706,"strand":"-","type":"gene"},"OPG061":{"end":41884,"seqid":"resources/genome_annotation.gff3","start":41189,"strand":"-","type":"gene"},"OPG062":{"end":42252,"seqid":"resources/genome_annotation.gff3","start":41947,"strand":"+","type":"gene"},"OPG063":{"end":43688,"seqid":"resources/genome_annotation.gff3","start":42249,"strand":"-","type":"gene"},"OPG064":{"end":45898,"seqid":"resources/genome_annotation.gff3","start":43685,"strand":"-","type":"gene"},"OPG065":{"end":46483,"seqid":"resources/genome_annotation.gff3","start":46022,"strand":"-","type":"gene"},"OPG066":{"end":47428,"seqid":"resources/genome_annotation.gff3","start":46649,"strand":"-","type":"gene"},"OPG068":{"end":49904,"seqid":"resources/genome_annotation.gff3","start":48201,"strand":"+","type":"gene"},"OPG069":{"end":50486,"seqid":"resources/genome_annotation.gff3","start":49986,"strand":"+","type":"gene"},"OPG070":{"end":51411,"seqid":"resources/genome_annotation.gff3","start":50590,"strand":"+","type":"gene"},"OPG071":{"end":54438,"seqid":"resources/genome_annotation.gff3","start":51418,"strand":"-","type":"gene"},"OPG072":{"end":54757,"seqid":"resources/genome_annotation.gff3","start":54470,"strand":"+","type":"gene"},"OPG073":{"end":55141,"seqid":"resources/genome_annotation.gff3","start":54752,"strand":"-","type":"gene"},"OPG074":{"end":57125,"seqid":"resources/genome_annotation.gff3","start":55128,"strand":"-","type":"gene"},"OPG075":{"end":57498,"seqid":"resources/genome_annotation.gff3","start":57172,"strand":"-","type":"gene"},"OPG076":{"end":57630,"seqid":"resources/genome_annotation.gff3","start":57523,"strand":"-","type":"gene"},"OPG077":{"end":58583,"seqid":"resources/genome_annotation.gff3","start":57645,"strand":"-","type":"gene"},"OPG078":{"end":58811,"seqid":"resources/genome_annotation.gff3","start":58590,"strand":"-","type":"gene"},"OPG079":{"end":59621,"seqid":"resources/genome_annotation.gff3","start":58812,"strand":"-","type":"gene"},"OPG080":{"end":62018,"seqid":"resources/genome_annotation.gff3","start":59703,"strand":"-","type":"gene"},"OPG081":{"end":62285,"seqid":"resources/genome_annotation.gff3","start":62046,"strand":"-","type":"gene"},"OPG082":{"end":63452,"seqid":"resources/genome_annotation.gff3","start":62304,"strand":"-","type":"gene"},"OPG083":{"end":64716,"seqid":"resources/genome_annotation.gff3","start":63445,"strand":"-","type":"gene"},"OPG084":{"end":66752,"seqid":"resources/genome_annotation.gff3","start":64722,"strand":"+","type":"gene"},"OPG085":{"end":68531,"seqid":"resources/genome_annotation.gff3","start":66756,"strand":"-","type":"gene"},"OPG086":{"end":68863,"seqid":"resources/genome_annotation.gff3","start":68528,"strand":"-","type":"gene"},"OPG087":{"end":69519,"seqid":"resources/genome_annotation.gff3","start":68857,"strand":"+","type":"gene"},"OPG088":{"end":69863,"seqid":"resources/genome_annotation.gff3","start":69489,"strand":"-","type":"gene"},"OPG089":{"end":71170,"seqid":"resources/genome_annotation.gff3","start":69866,"strand":"+","type":"gene"},"OPG090":{"end":71370,"seqid":"resources/genome_annotation.gff3","start":71179,"strand":"+","type":"gene"},"OPG091":{"end":71867,"seqid":"resources/genome_annotation.gff3","start":71370,"strand":"+","type":"gene"},"OPG092":{"end":72947,"seqid":"resources/genome_annotation.gff3","start":71832,"strand":"-","type":"gene"},"OPG093":{"end":73760,"seqid":"resources/genome_annotation.gff3","start":72978,"strand":"+","type":"gene"},"OPG094":{"end":74802,"seqid":"resources/genome_annotation.gff3","start":73780,"strand":"+","type":"gene"},"OPG095":{"end":75555,"seqid":"resources/genome_annotation.gff3","start":74803,"strand":"+","type":"gene"},"OPG096":{"end":75865,"seqid":"resources/genome_annotation.gff3","start":75587,"strand":"+","type":"gene"},"OPG097":{"end":76875,"seqid":"resources/genome_annotation.gff3","start":75841,"strand":"-","type":"gene"},"OPG098":{"end":77655,"seqid":"resources/genome_annotation.gff3","start":76900,"strand":"+","type":"gene"},"OPG099":{"end":78051,"seqid":"resources/genome_annotation.gff3","start":77665,"strand":"+","type":"gene"},"OPG100":{"end":78466,"seqid":"resources/genome_annotation.gff3","start":78008,"strand":"+","type":"gene"},"OPG101":{"end":79019,"seqid":"resources/genome_annotation.gff3","start":78486,"strand":"+","type":"gene"},"OPG102":{"end":80086,"seqid":"resources/genome_annotation.gff3","start":79085,"strand":"+","type":"gene"},"OPG103":{"end":80558,"seqid":"resources/genome_annotation.gff3","start":80001,"strand":"+","type":"gene"},"OPG104":{"end":81019,"seqid":"resources/genome_annotation.gff3","start":80618,"strand":"-","type":"gene"},"OPG105":{"end":84986,"seqid":"resources/genome_annotation.gff3","start":81126,"strand":"+","type":"gene"},"OPG106":{"end":85498,"seqid":"resources/genome_annotation.gff3","start":84983,"strand":"-","type":"gene"},"OPG107":{"end":86081,"seqid":"resources/genome_annotation.gff3","start":85512,"strand":"+","type":"gene"},"OPG108":{"end":87059,"seqid":"resources/genome_annotation.gff3","start":86085,"strand":"-","type":"gene"},"OPG109":{"end":89447,"seqid":"resources/genome_annotation.gff3","start":87060,"strand":"-","type":"gene"},"OPG110":{"end":90264,"seqid":"resources/genome_annotation.gff3","start":89632,"strand":"+","type":"gene"},"OPG111":{"end":91209,"seqid":"resources/genome_annotation.gff3","start":90265,"strand":"+","type":"gene"},"OPG112":{"end":91687,"seqid":"resources/genome_annotation.gff3","start":91247,"strand":"+","type":"gene"},"OPG113":{"end":94268,"seqid":"resources/genome_annotation.gff3","start":91731,"strand":"+","type":"gene"},"OPG114":{"end":94667,"seqid":"resources/genome_annotation.gff3","start":94227,"strand":"-","type":"gene"},"OPG115":{"end":95361,"seqid":"resources/genome_annotation.gff3","start":94660,"strand":"+","type":"gene"},"OPG116":{"end":96017,"seqid":"resources/genome_annotation.gff3","start":95361,"strand":"+","type":"gene"},"OPG117":{"end":98406,"seqid":"resources/genome_annotation.gff3","start":96049,"strand":"+","type":"gene"},"OPG118":{"end":100359,"seqid":"resources/genome_annotation.gff3","start":98446,"strand":"+","type":"gene"},"OPG119":{"end":100871,"seqid":"resources/genome_annotation.gff3","start":100386,"strand":"+","type":"gene"},"OPG120":{"end":101748,"seqid":"resources/genome_annotation.gff3","start":100834,"strand":"-","type":"gene"},"OPG121":{"end":102431,"seqid":"resources/genome_annotation.gff3","start":101790,"strand":"+","type":"gene"},"OPG122":{"end":103174,"seqid":"resources/genome_annotation.gff3","start":102428,"strand":"+","type":"gene"},"OPG123":{"end":105070,"seqid":"resources/genome_annotation.gff3","start":103175,"strand":"-","type":"gene"},"OPG124":{"end":105968,"seqid":"resources/genome_annotation.gff3","start":105105,"strand":"-","type":"gene"},"OPG125":{"end":107654,"seqid":"resources/genome_annotation.gff3","start":105999,"strand":"-","type":"gene"},"OPG126":{"end":108130,"seqid":"resources/genome_annotation.gff3","start":107678,"strand":"-","type":"gene"},"OPG127":{"end":108825,"seqid":"resources/genome_annotation.gff3","start":108151,"strand":"-","type":"gene"},"OPG128":{"end":109055,"seqid":"resources/genome_annotation.gff3","start":108822,"strand":"-","type":"gene"},"OPG129":{"end":111004,"seqid":"resources/genome_annotation.gff3","start":109070,"strand":"-","type":"gene"},"OPG130":{"end":111902,"seqid":"resources/genome_annotation.gff3","start":111057,"strand":"-","type":"gene"},"OPG131":{"end":112425,"seqid":"resources/genome_annotation.gff3","start":111940,"strand":"+","type":"gene"},"OPG132":{"end":113540,"seqid":"resources/genome_annotation.gff3","start":112422,"strand":"-","type":"gene"},"OPG133":{"end":115696,"seqid":"resources/genome_annotation.gff3","start":113564,"strand":"-","type":"gene"},"OPG134":{"end":116628,"seqid":"resources/genome_annotation.gff3","start":115750,"strand":"+","type":"gene"},"OPG135":{"end":116911,"seqid":"resources/genome_annotation.gff3","start":116609,"strand":"-","type":"gene"},"OPG136":{"end":119587,"seqid":"resources/genome_annotation.gff3","start":116912,"strand":"-","type":"gene"},"OPG137":{"end":120558,"seqid":"resources/genome_annotation.gff3","start":119602,"strand":"+","type":"gene"},"OPG138":{"end":121132,"seqid":"resources/genome_annotation.gff3","start":120560,"strand":"-","type":"gene"},"OPG139":{"end":121368,"seqid":"resources/genome_annotation.gff3","start":121156,"strand":"-","type":"gene"},"OPG140":{"end":121746,"seqid":"resources/genome_annotation.gff3","start":121474,"strand":"-","type":"gene"},"OPG141":{"end":121924,"seqid":"resources/genome_annotation.gff3","start":121763,"strand":"-","type":"gene"},"OPG142":{"end":122198,"seqid":"resources/genome_annotation.gff3","start":121914,"strand":"-","type":"gene"},"OPG143":{"end":123315,"seqid":"resources/genome_annotation.gff3","start":122182,"strand":"-","type":"gene"},"OPG144":{"end":123932,"seqid":"resources/genome_annotation.gff3","start":123318,"strand":"-","type":"gene"},"OPG145":{"end":125425,"seqid":"resources/genome_annotation.gff3","start":123947,"strand":"+","type":"gene"},"OPG146":{"end":125639,"seqid":"resources/genome_annotation.gff3","start":125406,"strand":"-","type":"gene"},"OPG147":{"end":125987,"seqid":"resources/genome_annotation.gff3","start":125640,"strand":"-","type":"gene"},"OPG148":{"end":127266,"seqid":"resources/genome_annotation.gff3","start":125986,"strand":"+","type":"gene"},"OPG149":{"end":127759,"seqid":"resources/genome_annotation.gff3","start":127196,"strand":"+","type":"gene"},"OPG150":{"end":128927,"seqid":"resources/genome_annotation.gff3","start":127779,"strand":"+","type":"gene"},"OPG151":{"end":132418,"seqid":"resources/genome_annotation.gff3","start":128924,"strand":"+","type":"gene"},"OPG153":{"end":137667,"seqid":"resources/genome_annotation.gff3","start":136138,"strand":"-","type":"gene"},"OPG154":{"end":138050,"seqid":"resources/genome_annotation.gff3","start":137718,"strand":"-","type":"gene"},"OPG155":{"end":138491,"seqid":"resources/genome_annotation.gff3","start":138051,"strand":"-","type":"gene"},"OPG156":{"end":139409,"seqid":"resources/genome_annotation.gff3","start":138492,"strand":"-","type":"gene"},"OPG157":{"end":139608,"seqid":"resources/genome_annotation.gff3","start":139372,"strand":"-","type":"gene"},"OPG158":{"end":139769,"seqid":"resources/genome_annotation.gff3","start":139641,"strand":"-","type":"gene"},"OPG159":{"end":140205,"seqid":"resources/genome_annotation.gff3","start":139768,"strand":"+","type":"gene"},"OPG160":{"end":141074,"seqid":"resources/genome_annotation.gff3","start":140172,"strand":"-","type":"gene"},"OPG161":{"end":141647,"seqid":"resources/genome_annotation.gff3","start":141102,"strand":"+","type":"gene"},"OPG162":{"end":142158,"seqid":"resources/genome_annotation.gff3","start":141652,"strand":"+","type":"gene"},"OPG163":{"end":142732,"seqid":"resources/genome_annotation.gff3","start":142202,"strand":"+","type":"gene"},"OPG164":{"end":143464,"seqid":"resources/genome_annotation.gff3","start":142778,"strand":"+","type":"gene"},"OPG165":{"end":144322,"seqid":"resources/genome_annotation.gff3","start":143516,"strand":"+","type":"gene"},"OPG166":{"end":144577,"seqid":"resources/genome_annotation.gff3","start":144398,"strand":"+","type":"gene"},"OPG167":{"end":145407,"seqid":"resources/genome_annotation.gff3","start":144574,"strand":"-","type":"gene"},"OPG170":{"end":146778,"seqid":"resources/genome_annotation.gff3","start":146113,"strand":"-","type":"gene"},"OPG171":{"end":147389,"seqid":"resources/genome_annotation.gff3","start":146988,"strand":"+","type":"gene"},"OPG172":{"end":148017,"seqid":"resources/genome_annotation.gff3","start":147427,"strand":"+","type":"gene"},"OPG173":{"end":148261,"seqid":"resources/genome_annotation.gff3","start":148037,"strand":"+","type":"gene"},"OPG174":{"end":149395,"seqid":"resources/genome_annotation.gff3","start":148355,"strand":"-","type":"gene"},"OPG175":{"end":149819,"seqid":"resources/genome_annotation.gff3","start":149442,"strand":"+","type":"gene"},"OPG176":{"end":150531,"seqid":"resources/genome_annotation.gff3","start":149809,"strand":"+","type":"gene"},"OPG178":{"end":152123,"seqid":"resources/genome_annotation.gff3","start":151509,"strand":"+","type":"gene"},"OPG180":{"end":154371,"seqid":"resources/genome_annotation.gff3","start":152692,"strand":"+","type":"gene"},"OPG181":{"end":155416,"seqid":"resources/genome_annotation.gff3","start":154412,"strand":"+","type":"gene"},"OPG185":{"end":159858,"seqid":"resources/genome_annotation.gff3","start":158917,"strand":"+","type":"gene"},"OPG187":{"end":161533,"seqid":"resources/genome_annotation.gff3","start":160622,"strand":"+","type":"gene"},"OPG188":{"end":163107,"seqid":"resources/genome_annotation.gff3","start":161596,"strand":"+","type":"gene"},"OPG189":{"end":165018,"seqid":"resources/genome_annotation.gff3","start":163333,"strand":"+","type":"gene"},"OPG190":{"end":166075,"seqid":"resources/genome_annotation.gff3","start":165122,"strand":"+","type":"gene"},"OPG191":{"end":166667,"seqid":"resources/genome_annotation.gff3","start":166161,"strand":"+","type":"gene"},"OPG192":{"end":167279,"seqid":"resources/genome_annotation.gff3","start":166731,"strand":"+","type":"gene"},"OPG193":{"end":168137,"seqid":"resources/genome_annotation.gff3","start":167334,"strand":"+","type":"gene"},"OPG195":{"end":168895,"seqid":"resources/genome_annotation.gff3","start":168230,"strand":"+","type":"gene"},"OPG197":{"end":169972,"seqid":"resources/genome_annotation.gff3","start":169670,"strand":"+","type":"gene"},"OPG198":{"end":170886,"seqid":"resources/genome_annotation.gff3","start":170038,"strand":"+","type":"gene"},"OPG199":{"end":172022,"seqid":"resources/genome_annotation.gff3","start":170988,"strand":"+","type":"gene"},"OPG200":{"end":172599,"seqid":"resources/genome_annotation.gff3","start":172150,"strand":"+","type":"gene"},"OPG204":{"end":175587,"seqid":"resources/genome_annotation.gff3","start":174532,"strand":"+","type":"gene"},"OPG205":{"end":178019,"seqid":"resources/genome_annotation.gff3","start":175656,"strand":"+","type":"gene"},"OPG208":{"end":180339,"seqid":"resources/genome_annotation.gff3","start":179266,"strand":"+","type":"gene"},"OPG209":{"end":181090,"seqid":"resources/genome_annotation.gff3","start":180518,"strand":"+","type":"gene"},"OPG210":{"end":186998,"seqid":"resources/genome_annotation.gff3","start":181356,"strand":"+","type":"gene"},"nuc":{"end":197209,"start":1,"strand":"+","type":"source"}},"colorings":[{"key":"clade_membership","title":"Clade","type":"categorical","scale":[["IIb","#DEA73C"]]},{"key":"gt","title":"Genotype","type":"categorical"},{"key":"outbreak","title":"Outbreak","type":"categorical","scale":[["hMPXV-1","#4C90C0"]]},{"key":"lineage","title":"Lineage","type":"categorical","scale":[["B.1","#4041C7"],["B.1.1","#3F53CD"],["B.1.2","#4064CF"],["B.1.3","#4375CD"],["C.1","#4784C8"],["B.1.4","#4C91BF"],["B.1.5","#539CB4"],["B.1.6","#5AA5A7"],["B.1.7","#63AC9A"],["B.1.8","#6CB28C"],["B.1.9","#77B67E"],["B.1.10","#82BA71"],["B.1.11","#8FBC66"],["B.1.12","#9CBE5B"],["B.1.13","#A9BD53"],["B.1.14","#B5BD4C"],["B.1.15","#C1BA46"],["B.1.16","#CDB642"],["B.1.17","#D6B03F"],["B.1.18","#DEA73B"],["B.1.19","#E39B39"],["B.1.20","#E68D36"]]},{"key":"date","title":"Collection Date","type":"categorical"},{"key":"host","title":"Host","type":"categorical"},{"key":"strain","title":"Strain name","type":"categorical"},{"key":"strain_display","title":"Pretty strain name","type":"categorical"},{"key":"region","title":"Region","type":"categorical","scale":[["Asia","#447CCD"],["Oceania","#5EA9A1"],["Africa","#8ABB6A"],["Europe","#BEBB48"],["South America","#E29E39"],["North America","#E2562B"]]},{"key":"country","title":"Country","type":"categorical","scale":[["Israel","#5E1D9D"],["Taiwan","#4D23AE"],["South Korea","#4432BD"],["Japan","#3F43C7"],["Australia","#3F56CE"],["South Africa","#4067CF"],["Portugal","#4379CD"],["Ireland","#4887C6"],["Spain","#4E95BD"],["United Kingdom","#559FB0"],["France","#5DA8A3"],["Belgium","#67AE94"],["Netherlands","#71B486"],["Switzerland","#7CB878"],["Germany","#89BB6B"],["Italy","#96BD60"],["Slovenia","#A3BE57"],["Sweden","#B1BD4E"],["Austria","#BDBB48"],["Czech Republic","#CAB843"],["Slovakia","#D3B23F"],["Romania","#DDAA3C"],["Finland","#E29E39"],["Brazil","#E69036"],["Peru","#E67F33"],["Colombia","#E56B2F"],["Mexico","#E1552B"],["USA","#DE3E27"],["Canada","#DB2823"]]}],"filters":["clade_membership","lineage","country","host","institution","region","strain_display","strain","date","outbreak"],"panels":["tree","entropy"],"extensions":{"nextclade":{"clade_node_attrs":[{"name":"outbreak","displayName":"Outbreak","description":""},{"name":"lineage","displayName":"Lineage","description":""}],"placement_mask_ranges":[{"begin":0,"end":1500},{"begin":133050,"end":133250},{"begin":136500,"end":136600},{"begin":140050,"end":140250},{"begin":146750,"end":147000},{"begin":150500,"end":150650},{"begin":169250,"end":169500},{"begin":169700,"end":169800},{"begin":173150,"end":173350},{"begin":179000,"end":179300},{"begin":190787,"end":197209}]}}},"tree":{"name":"NODE_0000001","node_attrs":{"div":0,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{},"labels":{"clade":"B.1"}},"children":[{"name":"ref_in_coord","node_attrs":{"div":0,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000000","node_attrs":{"div":0,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T607-","T608-","T609-","T133177-","C133178-","T133179-","T133180-","T133181-","C133182-","T133183-","C133184-","A133185-","A133186-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A196615-","A196616-","A196617-"]}},"children":[{"name":"ON682267","node_attrs":{"div":0,"accession":"ON682267","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI010"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON682267/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP205139","node_attrs":{"div":0,"accession":"OP205139","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000090"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205139/2022-05-25"},"date":{"value":"2022-05-25"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON880546","node_attrs":{"div":0,"accession":"ON880546","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3368/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880546/2022-06-02"},"date":{"value":"2022-06-02"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"ON631241","node_attrs":{"div":0,"accession":"ON631241","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"2022/2 SLO"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia"},"strain_display":{"value":"Slovenia/ON631241/2022-05-24"},"date":{"value":"2022-05-24"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON838940","node_attrs":{"div":0,"accession":"ON838940","author":{"author":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J.","value":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"4061"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Hospital Universitario La Paz, Microbiology"},"strain_display":{"value":"Spain/ON838940/2022-05-20"},"date":{"value":"2022-05-20"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP689666","node_attrs":{"div":0,"accession":"OP689666","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI513"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP689666/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR035655","node_attrs":{"div":0,"accession":"OR035655","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_49"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035655/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON983166","node_attrs":{"div":0,"accession":"ON983166","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3702/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON983166/2022-06-15"},"date":{"value":"2022-06-15"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OR035652","node_attrs":{"div":0,"accession":"OR035652","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_46"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035652/2022-08-02"},"date":{"value":"2022-08-02"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON808414","node_attrs":{"div":0,"accession":"ON808414","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"CVR_MPXV1b"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"strain_display":{"value":"United Kingdom/ON808414/2022-05-15"},"date":{"value":"2022-05-15"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"ON782022","node_attrs":{"div":0,"accession":"ON782022","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.,Sironen,T.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.,Sironen,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX-42/Finland/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"strain_display":{"value":"Finland/ON782022/2022-05-31"},"date":{"value":"2022-05-31"},"country":{"value":"Finland"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP382480","node_attrs":{"div":0,"accession":"OP382480","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00003"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382480/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP415195","node_attrs":{"div":0,"accession":"OP415195","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_96X1Vd_9000217"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415195/2022-03-XX"},"date":{"value":"2022-03-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP225969","node_attrs":{"div":0,"accession":"OP225969","author":{"author":"Gigante,C.M.,Ghinai,I.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.M.,Ghinai,I.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_IL0025"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP225969/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"ON880508","node_attrs":{"div":0,"accession":"ON880508","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3127/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880508/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"ON627808","node_attrs":{"div":0,"accession":"ON627808","author":{"author":"Young,E.L.,Hergert,J.,Oakeson,K.F.","value":"Young,E.L.,Hergert,J.,Oakeson,K.F."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/human/USA/UT-UPHL-82200022/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Department of Health, Utah Public Health Laboratory, USA"},"strain_display":{"value":"USA/ON627808/2022-05-20"},"date":{"value":"2022-05-20"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"ON803429","node_attrs":{"div":0,"accession":"ON803429","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2873/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON803429/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR087011","node_attrs":{"div":0,"accession":"OR087011","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_202/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR087011/2022-08-08"},"date":{"value":"2022-08-08"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON880421","node_attrs":{"div":0,"accession":"ON880421","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/UZ_REGA_5/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Rega Institute, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/ON880421/2022-05-27"},"date":{"value":"2022-05-27"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON755040","node_attrs":{"div":0,"accession":"ON755040","author":{"author":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O.","value":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_IRBA22-14"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IRBA, D.DNRBC/D.2MI/U.BACT"},"strain_display":{"value":"France/ON755040/2022-05-20"},"date":{"value":"2022-05-20"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON880420","node_attrs":{"div":0,"accession":"ON880420","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/UZ_REGA_4/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Rega Institute, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/ON880420/2022-05-27"},"date":{"value":"2022-05-27"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON808417","node_attrs":{"div":0,"accession":"ON808417","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"CVR_MPXV1e"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"strain_display":{"value":"United Kingdom/ON808417/2022-05-15"},"date":{"value":"2022-05-15"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"ON649720","node_attrs":{"div":0,"accession":"ON649720","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0024/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"strain_display":{"value":"Portugal/ON649720/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"ON676703","node_attrs":{"div":0,"accession":"ON676703","author":{"author":"Gigante,C.M.,Ventura,J.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y.","value":"Gigante,C.M.,Ventura,J.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_CA001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"strain_display":{"value":"USA/ON676703/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON880422","node_attrs":{"div":0,"accession":"ON880422","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/UZ_REGA_6/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Rega Institute, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/ON880422/2022-05-27"},"date":{"value":"2022-05-27"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR759162","node_attrs":{"div":0,"accession":"OR759162","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL074/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759162/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["G850A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C196360T"]}}},{"name":"OP382482","node_attrs":{"div":0,"accession":"OP382482","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00005"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382482/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035663","node_attrs":{"div":0,"accession":"OR035663","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_57"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035663/2022-06-09"},"date":{"value":"2022-06-09"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP205117","node_attrs":{"div":0,"accession":"OP205117","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000159"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205117/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON803438","node_attrs":{"div":0,"accession":"ON803438","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2897/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON803438/2022-05-20"},"date":{"value":"2022-05-20"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP536747","node_attrs":{"div":0,"accession":"OP536747","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000365"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536747/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035654","node_attrs":{"div":0,"accession":"OR035654","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_48"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035654/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP205114","node_attrs":{"div":0,"accession":"OP205114","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000152"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205114/2022-05-16"},"date":{"value":"2022-05-16"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035713","node_attrs":{"div":0,"accession":"OR035713","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_107"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035713/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON880419","node_attrs":{"div":0,"accession":"ON880419","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/UZ_REGA_3/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Rega Institute, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/ON880419/2022-05-27"},"date":{"value":"2022-05-27"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035704","node_attrs":{"div":0,"accession":"OR035704","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_98"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035704/2022-05-31"},"date":{"value":"2022-05-31"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G179023A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON649879","node_attrs":{"div":0,"accession":"ON649879","author":{"author":"Israeli,O.,Guedj-Dana,Y.,Lazar,S.,Shifman,O.,Erez,N.,Weiss,S.,Paran,N.,Israely,T.,Schuster,O.,Zvi,A.,Beth-Din,A.,Cohen Gihon,I.","value":"Israeli,O.,Guedj-Dana,Y.,Lazar,S.,Shifman,O.,Erez,N.,Weiss,S.,Paran,N.,Israely,T.,Schuster,O.,Zvi,A.,Beth-Din,A.,Cohen Gihon,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_ISR001_2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel"},"strain_display":{"value":"Israel/ON649879/2022-05-20"},"date":{"value":"2022-05-20"},"country":{"value":"Israel"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"ON880530","node_attrs":{"div":0,"accession":"ON880530","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3162/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880530/2022-05-29"},"date":{"value":"2022-05-29"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"OR264442","node_attrs":{"div":0,"accession":"OR264442","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"60_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264442/2022-08-22"},"date":{"value":"2022-08-22"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["C173173T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035678","node_attrs":{"div":0,"accession":"OR035678","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_72"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035678/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON563414","node_attrs":{"div":0,"accession":"ON563414","author":{"author":"Gigante,C.M.,Smole,S.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Brown,C.,Li,Y.","value":"Gigante,C.M.,Smole,S.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Brown,C.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_MA001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"strain_display":{"value":"USA/ON563414/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON585034","node_attrs":{"div":0,"accession":"ON585034","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0007/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"strain_display":{"value":"Portugal/ON585034/2022-05-15"},"date":{"value":"2022-05-15"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A188351-"]}}},{"name":"OP160532","node_attrs":{"div":1,"accession":"OP160532","author":{"author":"Tutu van Furth AM,van der Kuip M,van Els AL,Fievez LC,van Rijckevorsel GG,van den Ouden A,Jonges M,Welkers MR,Welkers,M.,Jonges,M.","value":"Tutu van Furth AM,van der Kuip M,van Els AL,Fievez LC,van Rijckevorsel GG,van den Ouden A,Jonges M,Welkers MR,Welkers,M.,Jonges,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Netherlands/NH-AUMC-0001/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention"},"strain_display":{"value":"Netherlands/OP160532/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Netherlands"}},"branch_attrs":{"mutations":{"nuc":["A148207T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G191845A","A196614-"],"OPG173":["E57D"]},"labels":{"aa":"OPG173: E57D"}}},{"name":"OP150926","node_attrs":{"div":0,"accession":"OP150926","author":{"author":"Gigante,C.,Goldoft,M.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Holshue,M.,Li,Y.","value":"Gigante,C.,Goldoft,M.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Holshue,M.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_PA001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP150926/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP133007","node_attrs":{"div":2,"accession":"OP133007","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1536480/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP133007/2022-07-22"},"date":{"value":"2022-07-22"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{"nuc":["A28532-","G32715A","G110407A","T133099-","T133100-","T133101-","T133102-","A173189G","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG044":["M148-"],"OPG049":["S146F"]},"labels":{"aa":"OPG044: M148-; OPG049: S146F"}}},{"name":"OP120937","node_attrs":{"div":1,"accession":"OP120937","author":{"author":"Aja-Macaya,P.,Rumbo-Feal,S.,Poza,M.,Canizares,A.,Vallejo,J.A.,Bou,G.","value":"Aja-Macaya,P.,Rumbo-Feal,S.,Poza,M.,Canizares,A.,Vallejo,J.A.,Bou,G."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MP01CHUAC"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Biomedical research institute (INIBIC), Microbiology"},"strain_display":{"value":"Spain/OP120937/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["G150330A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP133006","node_attrs":{"div":4,"accession":"OP133006","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1532243/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP133006/2022-07-06"},"date":{"value":"2022-07-06"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{"nuc":["A28532-","C122511T","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","G151801A","C153984T","G169886A","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG044":["M148-"],"OPG143":["E269K"],"OPG178":["G98E"],"OPG197":["E73K"]},"labels":{"aa":"OPG044: M148-; OPG143: E269K; OPG178: G98E; OPG197: E73K"}}},{"name":"OP062232","node_attrs":{"div":1,"accession":"OP062232","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Jolly,G.,Griffiths,E.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Jolly,G.,Griffiths,E.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3909/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP062232/2022-06-27"},"date":{"value":"2022-06-27"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T","G75169A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG095":["D123N"]},"labels":{"aa":"OPG095: D123N"}}},{"name":"OP022170","node_attrs":{"div":1,"accession":"OP022170","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_5"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP022170/2022-05-16"},"date":{"value":"2022-05-16"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C178569T","-179183T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OP022171","node_attrs":{"div":0,"accession":"OP022171","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_6"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP022171/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179208C","-179209A","-179210T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"ON959134","node_attrs":{"div":1,"accession":"ON959134","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_NY003"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"strain_display":{"value":"USA/ON959134/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C98368T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON927243","node_attrs":{"div":1,"accession":"ON927243","author":{"author":"Palomino-Cabrera,R.,Penas-Utrilla,D.,Buenestado-Serrano,S.,Perez-Lago,L.,Herranz Martin,M.,Veintimilla,C.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Palomino-Cabrera,R.,Penas-Utrilla,D.,Buenestado-Serrano,S.,Perez-Lago,L.,Herranz Martin,M.,Veintimilla,C.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/Spain/MD-HGUGM-6642566/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"HGUGM, Microbial Genomics"},"strain_display":{"value":"Spain/ON927243/2022-06-21"},"date":{"value":"2022-06-21"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","C187154T"]}}},{"name":"ON880543","node_attrs":{"div":3,"accession":"ON880543","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3357/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880543/2022-06-02"},"date":{"value":"2022-06-02"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["T606-","C17810T","G62130A","C157792T","A196614-"],"OPG030":["M8I"]},"labels":{"aa":"OPG030: M8I"}}},{"name":"ON880531","node_attrs":{"div":0,"accession":"ON880531","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3165/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880531/2022-05-29"},"date":{"value":"2022-05-29"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"ON880521","node_attrs":{"div":0,"accession":"ON880521","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2858/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880521/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"ON880525","node_attrs":{"div":0,"accession":"ON880525","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3086/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880525/2022-05-25"},"date":{"value":"2022-05-25"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"ON880509","node_attrs":{"div":0,"accession":"ON880509","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3137/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880509/2022-05-29"},"date":{"value":"2022-05-29"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"ON872184","node_attrs":{"div":5,"accession":"ON872184","author":{"author":"Fletcher,N.,Gonzalez,G.,Meredith,L.,Purves,K.,Carr,M.,Dean,J.,Keogan,B.,Crowley,B.,Lyons,F.,O'Reilly,S.,Gautier,V.,Mallon,P.,Gordon,S.,Connell,J.,De Gascun,C.F.","value":"Fletcher,N.,Gonzalez,G.,Meredith,L.,Purves,K.,Carr,M.,Dean,J.,Keogan,B.,Crowley,B.,Lyons,F.,O'Reilly,S.,Gautier,V.,Mallon,P.,Gordon,S.,Connell,J.,De Gascun,C.F."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"WA-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University College Dublin, National Virus Reference Laboratory"},"strain_display":{"value":"Ireland/ON872184/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Ireland"}},"branch_attrs":{"mutations":{"nuc":["T48785C","G49636A","C50017T","T72809C","G178541A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG068":["G479E"],"OPG069":["T11I"],"OPG092":["K47E"]},"labels":{"aa":"OPG068: G479E; OPG069: T11I; OPG092: K47E"}}},{"name":"ON838939","node_attrs":{"div":2,"accession":"ON838939","author":{"author":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J.","value":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"8887"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Hospital Universitario La Paz, Microbiology"},"strain_display":{"value":"Spain/ON838939/2022-06-06"},"date":{"value":"2022-06-06"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["G90838A","G94328A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG111":["D192N"]},"labels":{"aa":"OPG111: D192N"}}},{"name":"ON843171","node_attrs":{"div":0,"accession":"ON843171","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0030/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/ON843171/2022-05-26"},"date":{"value":"2022-05-26"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C133103T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON843164","node_attrs":{"div":0,"accession":"ON843164","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0037/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/ON843164/2022-05-18"},"date":{"value":"2022-05-18"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C133103T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON808416","node_attrs":{"div":1,"accession":"ON808416","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"CVR_MPXV1d"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"strain_display":{"value":"United Kingdom/ON808416/2022-05-15"},"date":{"value":"2022-05-15"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["G20576A","T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"ON808415","node_attrs":{"div":0,"accession":"ON808415","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"CVR_MPXV1c"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"strain_display":{"value":"United Kingdom/ON808415/2022-05-15"},"date":{"value":"2022-05-15"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"ON803444","node_attrs":{"div":1,"accession":"ON803444","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2969/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON803444/2022-05-24"},"date":{"value":"2022-05-24"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["G21069A"]}}},{"name":"ON803427","node_attrs":{"div":0,"accession":"ON803427","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2861/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON803427/2022-05-18"},"date":{"value":"2022-05-18"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON803436","node_attrs":{"div":0,"accession":"ON803436","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2894/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON803436/2022-05-20"},"date":{"value":"2022-05-20"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["G143768-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG165":["G85-"]},"labels":{"aa":"OPG165: G85-"}}},{"name":"ON780016","node_attrs":{"div":0,"accession":"ON780016","author":{"author":"Rueca,M.,Giombini,E.,Gruber,C.E.M.,Gramigna,G.,Mazzotta,V.,Carletti,F.,Lapa,D.,Pittalis,S.,Puro,V.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F.","value":"Rueca,M.,Giombini,E.,Gruber,C.E.M.,Gramigna,G.,Mazzotta,V.,Carletti,F.,Lapa,D.,Pittalis,S.,Puro,V.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"INMI-Pt3"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology"},"strain_display":{"value":"Italy/ON780016/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A"]}}},{"name":"ON745215","node_attrs":{"div":0,"accession":"ON745215","author":{"author":"Giombini,E.,Gruber,C.E.M.,Rueca,M.,Gramigna,G.,VIta,S.,Carletti,F.,D'Abramo,A.,Lapa,D.,Puro,V.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Specchiarello,E.,Vairo,F.,Vaia,F.,Garbuglia,A.R.,Nicastri,E.,Antinori,A.,GIrardi,E.,Maggi,F.","value":"Giombini,E.,Gruber,C.E.M.,Rueca,M.,Gramigna,G.,VIta,S.,Carletti,F.,D'Abramo,A.,Lapa,D.,Puro,V.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Specchiarello,E.,Vairo,F.,Vaia,F.,Garbuglia,A.R.,Nicastri,E.,Antinori,A.,GIrardi,E.,Maggi,F."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"INMI-Pt2"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology"},"strain_display":{"value":"Italy/ON745215/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["T591A","A592-","T593-","T595A","-607T","-608T","-609T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A"]}}},{"name":"ON745225","node_attrs":{"div":1,"accession":"ON745225","author":{"author":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/Spain/MD-HGUGM-66649483/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"HGUGM, Microbial Genomics"},"strain_display":{"value":"Spain/ON745225/2022-05-27"},"date":{"value":"2022-05-27"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["G50151A","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG069":["D56N"]},"labels":{"aa":"OPG069: D56N"}}},{"name":"ON682265","node_attrs":{"div":0,"accession":"ON682265","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI04"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON682265/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON682268","node_attrs":{"div":1,"accession":"ON682268","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI08"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON682268/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G4454A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C192756T"],"OPG003":["H52Y"],"OPG003_dup":["H52Y"]},"labels":{"aa":"OPG003: H52Y; OPG003_dup: H52Y"}}},{"name":"ON676705","node_attrs":{"div":1,"accession":"ON676705","author":{"author":"Gigante,C.M.,Atkinson,A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Murray,J.,Li,Y.","value":"Gigante,C.M.,Atkinson,A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Murray,J.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_UT001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"strain_display":{"value":"USA/ON676705/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","G28330A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG044":["M80I"]},"labels":{"aa":"OPG044: M80I"}}},{"name":"ON676706","node_attrs":{"div":0,"accession":"ON676706","author":{"author":"Gigante,C.M.,Atkinson,A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Murray,J.,Li,Y.","value":"Gigante,C.M.,Atkinson,A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Murray,J.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_UT002"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"strain_display":{"value":"USA/ON676706/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","T133102-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON676708","node_attrs":{"div":14,"accession":"ON676708","author":{"author":"Gigante,C.M.,Myers,R.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Blythe,D.,Li,Y.","value":"Gigante,C.M.,Myers,R.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Blythe,D.,Li,Y."},"strain":{"value":"MPXV_USA_2021_MD"},"clade_membership":{"value":"outgroup"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"strain_display":{"value":"USA/ON676708/2021-11-XX"},"date":{"value":"2021-11-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A3111G","T39139C","A73239G","A74205G","A77383G","C79348T","T84587C","C86979T","C133714T","T150469C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C151461A","A155795G","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","A170262G","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T183519C","T194099C"],"OPG057":["K353E"],"OPG093":["N88D"],"OPG094":["I142M"],"OPG098":["K162E"],"OPG176":["Y221H"],"OPG197":["T34-","D35-"],"OPG210":["S722P"]},"labels":{"aa":"OPG057: K353E; OPG093: N88D; OPG094: I142M; OPG098: K162E; OPG176: Y221H; OPG197: T34-, D35-; OPG210: S722P","clade":"outgroup"}}},{"name":"ON649717","node_attrs":{"div":1,"accession":"ON649717","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0019/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"strain_display":{"value":"Portugal/ON649717/2022-05-21"},"date":{"value":"2022-05-21"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C118296T"],"OPG136":["R431K"]},"labels":{"aa":"OPG136: R431K"}}},{"name":"ON644344","node_attrs":{"div":0,"accession":"ON644344","author":{"author":"Licastro,D.,DeGasperi,M.,Negri,C.,Piscianz,E.,Koncan,R.,Dal Monego,S.,Segat,L.,D'Agaro,P.","value":"Licastro,D.,DeGasperi,M.,Negri,C.,Piscianz,E.,Koncan,R.,Dal Monego,S.,Segat,L.,D'Agaro,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_FVG-ITA_01_2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Genomics & Epigenomics, AREA Science Park, Italy"},"strain_display":{"value":"Italy/ON644344/2022-05-25"},"date":{"value":"2022-05-25"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["C334-","A335-","C133077T","T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T173317-","G173318-","G173319-","G173320-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON619838","node_attrs":{"div":2,"accession":"ON619838","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_4"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Research & Evaluation, UKHSA, UK"},"strain_display":{"value":"United Kingdom/ON619838/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C147011T","G172095A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"ON622712","node_attrs":{"div":1,"accession":"ON622712","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/UZ_REGA_1/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Microbiology, Immunology & Transplantation, KU Leuven, Rega Institute, Belgium"},"strain_display":{"value":"Belgium/ON622712/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C46125T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG065":["R120K"]},"labels":{"aa":"OPG065: R120K"}}},{"name":"ON619836","node_attrs":{"div":2,"accession":"ON619836","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_2"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Research & Evaluation, UKHSA, UK"},"strain_display":{"value":"United Kingdom/ON619836/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C7259T","C33832T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG052":["R55Q"]},"labels":{"aa":"OPG052: R55Q"}}},{"name":"ON622720","node_attrs":{"div":0,"accession":"ON622720","author":{"author":"Laubscher,F.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Schibler,M.,Kaiser,L.,Renzoni,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-CH-38156923/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Laboratory of Viorology, University Hospital of Geneva, Switzerland"},"strain_display":{"value":"Switzerland/ON622720/2022-05-24"},"date":{"value":"2022-05-24"},"country":{"value":"Switzerland"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON619835","node_attrs":{"div":0,"accession":"ON619835","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Research & Evaluation, UKHSA, UK"},"strain_display":{"value":"United Kingdom/ON619835/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179179T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"ON614676","node_attrs":{"div":0,"accession":"ON614676","author":{"author":"Gruber,C.E.M.,Rueca,M.,Gramigna,G.,Carletti,F.,Butera,O.,Fabeni,L.,Specchiarello,E.,Meschi,S.,Colavita,F.,Minosse,C.,Francalancia,M.,Lapa,D.,Garbuglia,A.R.,Giombini,E.","value":"Gruber,C.E.M.,Rueca,M.,Gramigna,G.,Carletti,F.,Butera,O.,Fabeni,L.,Specchiarello,E.,Meschi,S.,Colavita,F.,Minosse,C.,Francalancia,M.,Lapa,D.,Garbuglia,A.R.,Giombini,E."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"INMI-Pt1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Laboratory of Virology, INMI Lazzaro Spallanzani IRCCS, Italy"},"strain_display":{"value":"Italy/ON614676/2022-05-18"},"date":{"value":"2022-05-18"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"ON615424","node_attrs":{"div":2,"accession":"ON615424","author":{"author":"Oude Munnink,B.B.,Boter,M.,Wellers,B.,Molenkamp,R.,Sikkema,R.S.,Koopmans,M.","value":"Oude Munnink,B.B.,Boter,M.,Wellers,B.,Molenkamp,R.,Sikkema,R.S.,Koopmans,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_2022_NL001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Public Health Virology, Erasmus Medical Centre, The Netherlands"},"strain_display":{"value":"Netherlands/ON615424/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Netherlands"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155611A","G171003A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","G179362-","G179363-","-196615A"],"OPG199":["E6K"]},"labels":{"aa":"OPG199: E6K"}}},{"name":"ON595760","node_attrs":{"div":0,"accession":"ON595760","author":{"author":"Laubscher,F.,Chudzinski,V.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinski,V.,Schibler,M.,Kaiser,L.,Renzoni,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-CH-38134631/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Laboratory of Viorology, University Hospital of Geneva, Switzerland"},"strain_display":{"value":"Switzerland/ON595760/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Switzerland"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","T133101-","T133102-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"]}}},{"name":"OP324500","node_attrs":{"div":5,"accession":"OP324500","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0186/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP324500/2022-06-28"},"date":{"value":"2022-06-28"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C774-","G775-","C4592T","G11462A","G89734A","C92865T","C133750T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G192618A","T196649-","C196650-"],"OPG003":["E6K"],"OPG003_dup":["E6K"],"OPG023":["S480L"],"OPG110":["E35K"]},"labels":{"aa":"OPG003: E6K; OPG003_dup: E6K; OPG023: S480L; OPG110: E35K"}}},{"name":"OP324540","node_attrs":{"div":0,"accession":"OP324540","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0232/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP324540/2022-06-21"},"date":{"value":"2022-06-21"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","C146816T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A","-196616T"]}}},{"name":"OP324492","node_attrs":{"div":0,"accession":"OP324492","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0177/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP324492/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A","-196616T"]}}},{"name":"OP324497","node_attrs":{"div":0,"accession":"OP324497","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0182/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP324497/2022-06-27"},"date":{"value":"2022-06-27"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP324485","node_attrs":{"div":1,"accession":"OP324485","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0170/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP324485/2022-07-03"},"date":{"value":"2022-07-03"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179853T"]}}},{"name":"OP324475","node_attrs":{"div":1,"accession":"OP324475","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0158/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP324475/2022-07-07"},"date":{"value":"2022-07-07"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G727-","T728-","A136552-","T136553-","C136554-","G150394A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T196639-","T196640-"],"OPG153":["D385-"],"OPG176":["E196K"]},"labels":{"aa":"OPG153: D385-; OPG176: E196K"}}},{"name":"OP324472","node_attrs":{"div":1,"accession":"OP324472","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0155/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP324472/2022-07-06"},"date":{"value":"2022-07-06"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G685-","T686-","C21998T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196686-","T196687-"],"OPG037":["D146N"]},"labels":{"aa":"OPG037: D146N"}}},{"name":"OP310056","node_attrs":{"div":5,"accession":"OP310056","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-089437/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP310056/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C21398T","C66975T","C97153T","G120238A","C136972T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG037":["D346N"],"OPG085":["M519I"],"OPG137":["E213K"]},"labels":{"aa":"OPG037: D346N; OPG085: M519I; OPG137: E213K"}}},{"name":"OP245359","node_attrs":{"div":0,"accession":"OP245359","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/PT0126/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP245359/2022-07-14"},"date":{"value":"2022-07-14"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP245346","node_attrs":{"div":0,"accession":"OP245346","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/PT0112/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP245346/2022-07-15"},"date":{"value":"2022-07-15"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP245311","node_attrs":{"div":1,"accession":"OP245311","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/PT0055/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP245311/2022-07-28"},"date":{"value":"2022-07-28"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C136572T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G158190A"],"OPG153":["E366K"]},"labels":{"aa":"OPG153: E366K"}}},{"name":"OP245316","node_attrs":{"div":1,"accession":"OP245316","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/PT0062/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP245316/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C15652T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP245308","node_attrs":{"div":0,"accession":"OP245308","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/PT0051/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP245308/2022-07-31"},"date":{"value":"2022-07-31"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP215217","node_attrs":{"div":2,"accession":"OP215217","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI218"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP215217/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C56259T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C188946T"]}}},{"name":"OP205095","node_attrs":{"div":2,"accession":"OP205095","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000107"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205095/2022-06-13"},"date":{"value":"2022-06-13"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-607T","C49892T","A56110G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG074":["L339S"]},"labels":{"aa":"OPG074: L339S"}}},{"name":"OP205092","node_attrs":{"div":4,"accession":"OP205092","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000104"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205092/2022-06-12"},"date":{"value":"2022-06-12"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-607T","G30128T","C164096T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188683T","C190269T","-196615A"],"OPG047":["P356Q"],"OPG189":["S255L"]},"labels":{"aa":"OPG047: P356Q; OPG189: S255L"}}},{"name":"OP185715","node_attrs":{"div":1,"accession":"OP185715","author":{"author":"Gigante,C.M.,Steidley,B.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Davizon,E.S.,Li,Y.","value":"Gigante,C.M.,Steidley,B.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Davizon,E.S.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_CO0002"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP185715/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C17437T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG030":["E133K"]},"labels":{"aa":"OPG030: E133K"}}},{"name":"OP440563","node_attrs":{"div":1,"accession":"OP440563","author":{"author":"Hemarajata,P.,Green,N.M.","value":"Hemarajata,P.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00061/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP440563/2022-07-20"},"date":{"value":"2022-07-20"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C2489T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G194721A"],"OPG002":["G88E"],"OPG002_dup":["G88E"]},"labels":{"aa":"OPG002: G88E; OPG002_dup: G88E"}}},{"name":"OP415274","node_attrs":{"div":1,"accession":"OP415274","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_i96eY5_9000346"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415274/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G180299A"],"OPG208":["G345E"]},"labels":{"aa":"OPG208: G345E"}}},{"name":"OP415281","node_attrs":{"div":0,"accession":"OP415281","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_hSAaEl_9000356"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415281/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP422245","node_attrs":{"div":0,"accession":"OP422245","author":{"author":"Laubscher,F.,Chudzinsk,V.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinsk,V.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-CH-38212023/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"strain_display":{"value":"Switzerland/OP422245/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Switzerland"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OP415226","node_attrs":{"div":0,"accession":"OP415226","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_k9tr7U_9000256"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415226/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["A173518-","G173519-","A173520-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP415196","node_attrs":{"div":0,"accession":"OP415196","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_96X1Vd_9000218"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415196/2022-03-XX"},"date":{"value":"2022-03-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP415220","node_attrs":{"div":0,"accession":"OP415220","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_EduQvV_9000249"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415220/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP415194","node_attrs":{"div":0,"accession":"OP415194","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_96X1Vd_9000216"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415194/2022-03-XX"},"date":{"value":"2022-03-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP414372","node_attrs":{"div":0,"accession":"OP414372","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0343/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414372/2022-05-26"},"date":{"value":"2022-05-26"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP414365","node_attrs":{"div":1,"accession":"OP414365","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0335/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414365/2022-05-29"},"date":{"value":"2022-05-29"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C144555T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG166":["S53L"]},"labels":{"aa":"OPG166: S53L"}}},{"name":"OP414380","node_attrs":{"div":0,"accession":"OP414380","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0351/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414380/2022-05-24"},"date":{"value":"2022-05-24"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"]}}},{"name":"OP414330","node_attrs":{"div":2,"accession":"OP414330","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0296/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414330/2022-06-08"},"date":{"value":"2022-06-08"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C110108T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A152274G"]}}},{"name":"OP414300","node_attrs":{"div":3,"accession":"OP414300","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0259/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414300/2022-06-19"},"date":{"value":"2022-06-19"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-607T","C23759T","G68825A","G117941A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"]}}},{"name":"OP414323","node_attrs":{"div":3,"accession":"OP414323","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0288/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414323/2022-06-13"},"date":{"value":"2022-06-13"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-607T","G58696A","G59086A","G90052A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"],"OPG078":["S39L"],"OPG079":["S179L"],"OPG110":["D141N"]},"labels":{"aa":"OPG078: S39L; OPG079: S179L; OPG110: D141N"}}},{"name":"OP414301","node_attrs":{"div":1,"accession":"OP414301","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0261/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414301/2022-06-19"},"date":{"value":"2022-06-19"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C184822T"],"OPG210":["T1156I"]},"labels":{"aa":"OPG210: T1156I"}}},{"name":"OP414297","node_attrs":{"div":0,"accession":"OP414297","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0256/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414297/2022-06-19"},"date":{"value":"2022-06-19"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP414294","node_attrs":{"div":1,"accession":"OP414294","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0253/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414294/2022-06-21"},"date":{"value":"2022-06-21"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","G142942A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-"}}},{"name":"OP382494","node_attrs":{"div":0,"accession":"OP382494","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00017"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382494/2022-07-22"},"date":{"value":"2022-07-22"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP382491","node_attrs":{"div":4,"accession":"OP382491","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00014"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382491/2022-07-22"},"date":{"value":"2022-07-22"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["T606-","G5444A","C20105T","A83680T","G101344A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C191766T"],"OPG015":["S238L"],"OPG015_dup":["S238L"],"OPG105":["D852V"]},"labels":{"aa":"OPG015: S238L; OPG015_dup: S238L; OPG105: D852V"}}},{"name":"OP382490","node_attrs":{"div":0,"accession":"OP382490","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00013"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382490/2022-07-20"},"date":{"value":"2022-07-20"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP382487","node_attrs":{"div":0,"accession":"OP382487","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00010"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382487/2022-07-18"},"date":{"value":"2022-07-18"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OP382484","node_attrs":{"div":0,"accession":"OP382484","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00007"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382484/2022-07-06"},"date":{"value":"2022-07-06"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP382483","node_attrs":{"div":0,"accession":"OP382483","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00006"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382483/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OP382478","node_attrs":{"div":1,"accession":"OP382478","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382478/2022-06-13"},"date":{"value":"2022-06-13"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["C178006T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG205":["S784F"]},"labels":{"aa":"OPG205: S784F"}}},{"name":"OP555503","node_attrs":{"div":6,"accession":"OP555503","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0409/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555503/2022-07-25"},"date":{"value":"2022-07-25"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C15057T","G67261A","G74252A","G95760A","G118335A","G132631A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG025":["D71N"],"OPG085":["S424L"],"OPG094":["R158K"],"OPG116":["A134T"],"OPG136":["S418F"]},"labels":{"aa":"OPG025: D71N; OPG085: S424L; OPG094: R158K; OPG116: A134T; OPG136: S418F"}}},{"name":"OP555501","node_attrs":{"div":2,"accession":"OP555501","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0406/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555501/2022-07-20"},"date":{"value":"2022-07-20"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G11924A","G41652A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG023":["S326L"],"OPG061":["S78F"]},"labels":{"aa":"OPG023: S326L; OPG061: S78F"}}},{"name":"OP536815","node_attrs":{"div":0,"accession":"OP536815","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000453"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536815/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP536813","node_attrs":{"div":3,"accession":"OP536813","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000451"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536813/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","G61102A","C77309T","C96440T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A"],"OPG080":["S306F"],"OPG098":["S137L"],"OPG117":["T131I"]},"labels":{"aa":"OPG080: S306F; OPG098: S137L; OPG117: T131I"}}},{"name":"OP536811","node_attrs":{"div":2,"accession":"OP536811","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000448"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536811/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C95004T","G111541A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG130":["S121F"]},"labels":{"aa":"OPG130: S121F"}}},{"name":"OP539896","node_attrs":{"div":2,"accession":"OP539896","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00111/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP539896/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","C104164T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C177339T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T196813-","A196814-","A196815-"],"OPG123":["E303K"],"OPG205":["L562F"]},"labels":{"aa":"OPG123: E303K; OPG205: L562F"}}},{"name":"OP536802","node_attrs":{"div":2,"accession":"OP536802","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000430"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536802/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-607T","C87702T","G150484A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG176":["D226N"]},"labels":{"aa":"OPG176: D226N"}}},{"name":"OP536739","node_attrs":{"div":3,"accession":"OP536739","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-USA-IL-IDPH-078"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"strain_display":{"value":"USA/OP536739/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C88308T","G97290A","C109462T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG129":["G515R"]},"labels":{"aa":"OPG129: G515R"}}},{"name":"OP536730","node_attrs":{"div":0,"accession":"OP536730","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-USA-IL-IDPH-069"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"strain_display":{"value":"USA/OP536730/2022-06-28"},"date":{"value":"2022-06-28"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"OP536682","node_attrs":{"div":1,"accession":"OP536682","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-USA-IL-IDPH-021"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"strain_display":{"value":"USA/OP536682/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C27368T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"OP524009","node_attrs":{"div":0,"accession":"OP524009","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI407"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP524009/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP523986","node_attrs":{"div":1,"accession":"OP523986","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI384"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP523986/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A4679T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T192531A"]}}},{"name":"OP484675","node_attrs":{"div":2,"accession":"OP484675","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI354"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP484675/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C87755T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G165247A"],"OPG109":["D565N"]},"labels":{"aa":"OPG109: D565N"}}},{"name":"OP484674","node_attrs":{"div":2,"accession":"OP484674","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI353"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP484674/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C32790T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C183220T"],"OPG049":["R121K"],"OPG210":["S622F"]},"labels":{"aa":"OPG049: R121K; OPG210: S622F"}}},{"name":"OP628484","node_attrs":{"div":3,"accession":"OP628484","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-088353/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP628484/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G44856T","C145137T","G162929A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG064":["P348H"],"OPG167":["D91N"],"OPG188":["R445K"]},"labels":{"aa":"OPG064: P348H; OPG167: D91N; OPG188: R445K"}}},{"name":"OP628489","node_attrs":{"div":4,"accession":"OP628489","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-092175/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP628489/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A93217G","G116130A","G151339A","G152202A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["K496R"]},"labels":{"aa":"OPG113: K496R"}}},{"name":"OP626127","node_attrs":{"div":1,"accession":"OP626127","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI489"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP626127/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C362T","C148390T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G196848A"],"OPG174":["E336K"]},"labels":{"aa":"OPG174: E336K"}}},{"name":"OP626117","node_attrs":{"div":3,"accession":"OP626117","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI479"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP626117/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C101074T","C128824T","G138682A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG150":["S349F"],"OPG156":["S243F"]},"labels":{"aa":"OPG150: S349F; OPG156: S243F"}}},{"name":"OP626105","node_attrs":{"div":1,"accession":"OP626105","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI467"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP626105/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C82676T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP605580","node_attrs":{"div":1,"accession":"OP605580","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-39-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605580/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["-607T","C179082T","C179091T","T179094A","C179100T","T179103A","C179109T","T179112A","C179118T","T179121A","C179127T","T179130A","C179136T","C179145T","T179148A","C179154T","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179239A","-179240T","-179241A","-179242T","-179243A","G189288A"]}}},{"name":"OP605573","node_attrs":{"div":0,"accession":"OP605573","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-31-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605573/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["-607T","A120644-","T120645-","T120646-","A120647-","G120648-","T120649-","G120650-","G120651-","G120652-","C120653-","A120654-","T120655-","C120656-","T120657-","T120658-","T120659-","T120660-","T120661-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179216A","-179217C","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG138":["M160-","P161-","T162-","N163-","K164-","K165-"]},"labels":{"aa":"OPG138: M160-, P161-, T162-, N163-, K164-, K165-"}}},{"name":"OP605575","node_attrs":{"div":0,"accession":"OP605575","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-33-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605575/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["-607T","C179154T","T179157A","C179163T","T179166A","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181T","-179182A","-179183T","-179184A","-179185A","-179186T","-179187A","-179188T","-179189A","-179190T","-179191A","-179192T","-179193A","-179194A","-179195T","-179196A","-179197T","-179198A","-179204T","-179205A","-179206T","-179207A","-179208T","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP605571","node_attrs":{"div":2,"accession":"OP605571","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-29-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605571/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["T264-","-607T","A86557T","A120644-","T120645-","T120646-","A120647-","G120648-","T120649-","G120650-","G120651-","G120652-","C120653-","A120654-","T120655-","C120656-","T120657-","T120658-","T120659-","T120660-","T120661-","C168661T","G173318A","G173319T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG108":["I168K"],"OPG138":["M160-","P161-","T162-","N163-","K164-","K165-"]},"labels":{"aa":"OPG108: I168K; OPG138: M160-, P161-, T162-, N163-, K164-, K165-"}}},{"name":"OP605582","node_attrs":{"div":10,"accession":"OP605582","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-41-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605582/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["C198-","-607T","C27187T","G176523A","C176524T","T176532G","G176536C","A176544T","A176550T","A176551G","T176552C","A176559C","T179059G","T179072A","G179076T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG043":["D257N"],"OPG205":["A290Y","I297L","N299C"]},"labels":{"aa":"OPG043: D257N; OPG205: A290Y, I297L, N299C"}}},{"name":"OP605569","node_attrs":{"div":2,"accession":"OP605569","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-27-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605569/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["-607T","G104565A","G130432A","T179166A","-179172C","-179173A","-179174G","-179175T","-179176A","-179177T","-179178C","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185G","-179186T","-179187T","-179188T","-179189A","-179190G","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197A","-179198T","-179199C","-179200C","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208A","-179209T","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217T","-179218A","-179219T","-179220C","-179221A","-179222T","-179223A","-179224T","-179225C","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236T","-179237T","-179238T","-179239A","-179240C","-179241A","-179242T","-179243A","T179248A","T179254A","G179256C","T179258G","A179261T","G179269A","T179271C","A179272G"],"OPG123":["S169F"],"OPG208":["D2N","I3V"]},"labels":{"aa":"OPG123: S169F; OPG208: D2N, I3V"}}},{"name":"OP605563","node_attrs":{"div":1,"accession":"OP605563","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-21-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605563/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","A29748T"],"OPG047":["*483K"]},"labels":{"aa":"OPG047: *483K"}}},{"name":"OP605561","node_attrs":{"div":0,"accession":"OP605561","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-19-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605561/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{}}},{"name":"OP605558","node_attrs":{"div":0,"accession":"OP605558","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-16-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605558/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP605554","node_attrs":{"div":0,"accession":"OP605554","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-11-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605554/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{}}},{"name":"OP603007","node_attrs":{"div":1,"accession":"OP603007","author":{"author":"Gigante,C.M.,Xia,D.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y.","value":"Gigante,C.M.,Xia,D.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_PA0007"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP603007/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","A153679T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-196615A"],"OPG180":["T330S"]},"labels":{"aa":"OPG180: T330S"}}},{"name":"OP555657","node_attrs":{"div":2,"accession":"OP555657","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0589/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555657/2022-08-24"},"date":{"value":"2022-08-24"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-607T","G2543A","G73164A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C194667T","-196615A"],"OPG002":["S70L"],"OPG002_dup":["S70L"],"OPG093":["E63K"]},"labels":{"aa":"OPG002: S70L; OPG002_dup: S70L; OPG093: E63K"}}},{"name":"OP555648","node_attrs":{"div":4,"accession":"OP555648","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0577/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555648/2022-09-09"},"date":{"value":"2022-09-09"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G2360A","A136552-","T136553-","C136554-","G146433A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C167425T","C189174T","C194850T"],"OPG002":["T131I"],"OPG002_dup":["T131I"],"OPG153":["D385-"],"OPG170":["H116Y"],"OPG193":["S31F"]},"labels":{"aa":"OPG002: T131I; OPG002_dup: T131I; OPG153: D385-; OPG170: H116Y; OPG193: S31F"}}},{"name":"OP555647","node_attrs":{"div":7,"accession":"OP555647","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0576/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555647/2022-09-05"},"date":{"value":"2022-09-05"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C28104T","C28175T","C46132T","G112246A","C125152T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A153083G","C162012T"],"OPG044":["S5L"],"OPG065":["D118N"],"OPG131":["D103N"],"OPG180":["K131R"]},"labels":{"aa":"OPG044: S5L; OPG065: D118N; OPG131: D103N; OPG180: K131R"}}},{"name":"OP555610","node_attrs":{"div":0,"accession":"OP555610","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0539/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555610/2022-08-23"},"date":{"value":"2022-08-23"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"]}}},{"name":"OP555612","node_attrs":{"div":3,"accession":"OP555612","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0541/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555612/2022-08-23"},"date":{"value":"2022-08-23"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G98166A","C124265T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C157632T"]}}},{"name":"OP555578","node_attrs":{"div":3,"accession":"OP555578","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0504/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555578/2022-08-13"},"date":{"value":"2022-08-13"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G70841A","G132625A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G182189A"],"OPG089":["E326K"]},"labels":{"aa":"OPG089: E326K"}}},{"name":"OP837355","node_attrs":{"div":0,"accession":"OP837355","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI593"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP837355/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP747062","node_attrs":{"div":3,"accession":"OP747062","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-106624/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP747062/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C90945T","C103417T","C173114T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG123":["E552K"]},"labels":{"aa":"OPG123: E552K"}}},{"name":"OP743991","node_attrs":{"div":0,"accession":"OP743991","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-092990/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP743991/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP748946","node_attrs":{"div":1,"accession":"OP748946","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00260/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP748946/2022-10-17"},"date":{"value":"2022-10-17"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C12684T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG023":["E73K"]},"labels":{"aa":"OPG023: E73K"}}},{"name":"OP743357","node_attrs":{"div":0,"accession":"OP743357","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200022/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Utah Public Health Laboratory"},"strain_display":{"value":"USA/OP743357/2022-05-21"},"date":{"value":"2022-05-21"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OP743358","node_attrs":{"div":0,"accession":"OP743358","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200023/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Utah Public Health Laboratory"},"strain_display":{"value":"USA/OP743358/2022-05-21"},"date":{"value":"2022-05-21"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OP743365","node_attrs":{"div":3,"accession":"OP743365","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200134/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Utah Public Health Laboratory"},"strain_display":{"value":"USA/OP743365/2022-07-27"},"date":{"value":"2022-07-27"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","C138921A","A149457T","C189536T"],"OPG005":["S113L"],"OPG153":["D385-"],"OPG175":["I6L"]},"labels":{"aa":"OPG005: S113L; OPG153: D385-; OPG175: I6L"}}},{"name":"OP715826","node_attrs":{"div":0,"accession":"OP715826","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI546"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP715826/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP693649","node_attrs":{"div":2,"accession":"OP693649","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT_INS_MPX_0039_L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP693649/2022-07-29"},"date":{"value":"2022-07-29"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A2840-","T2841-","C2842-","G127058A","G136194A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","T196865-","A196866-","G196867-"],"OPG148":["R358K"],"OPG153":["H492Y"]},"labels":{"aa":"OPG148: R358K; OPG153: H492Y"}}},{"name":"OP689665","node_attrs":{"div":0,"accession":"OP689665","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI512"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP689665/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OQ319136","node_attrs":{"div":0,"accession":"OQ319136","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI678"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ319136/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150564-","G150565-","A150566-","T150567-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OQ099609","node_attrs":{"div":1,"accession":"OQ099609","author":{"author":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_IL0031"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ099609/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G50617A","A173314-","T173315-","A173316-","T173317-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A"],"OPG070":["D10N"]},"labels":{"aa":"OPG070: D10N"}}},{"name":"OP920685","node_attrs":{"div":9,"accession":"OP920685","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00347/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP920685/2022-10-09"},"date":{"value":"2022-10-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C29308T","C54262T","C65348T","G69678A","G74672A","C76556T","C105161T","C144237T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G162016A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG046":["G141E"],"OPG094":["R298K"],"OPG097":["R107K"],"OPG124":["D270N"],"OPG165":["S241L"],"OPG188":["E141K"]},"labels":{"aa":"OPG046: G141E; OPG094: R298K; OPG097: R107K; OPG124: D270N; OPG165: S241L; OPG188: E141K"}}},{"name":"OP920696","node_attrs":{"div":3,"accession":"OP920696","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00358/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP920696/2022-11-05"},"date":{"value":"2022-11-05"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G15683A","C104028T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G184416A"],"OPG123":["G348E"],"OPG210":["D1021N"]},"labels":{"aa":"OPG123: G348E; OPG210: D1021N"}}},{"name":"OP935995","node_attrs":{"div":2,"accession":"OP935995","author":{"author":"Bajwa,M.I.,Miller,H.","value":"Bajwa,M.I.,Miller,H."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"B1118436"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Delaware Public Health Lab, Sequencing/Bioinformatics"},"strain_display":{"value":"USA/OP935995/2022-10-02"},"date":{"value":"2022-10-02"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C95099T","C135868T","A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG115":["S147L"],"OPG153":["D385-"]},"labels":{"aa":"OPG115: S147L; OPG153: D385-"}}},{"name":"OQ411312","node_attrs":{"div":1,"accession":"OQ411312","author":{"author":"Laubscher,F.,Chudzinsk,V.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinsk,V.,Schibler,M.,Kaiser,L.,Renzoni,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-CH-38292866/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"strain_display":{"value":"Switzerland/OQ411312/2022-06-08"},"date":{"value":"2022-06-08"},"country":{"value":"Switzerland"}},"branch_attrs":{"mutations":{"nuc":["C87764T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG109":["E562K"]},"labels":{"aa":"OPG109: E562K"}}},{"name":"OQ348875","node_attrs":{"div":3,"accession":"OQ348875","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000128/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDPH, VRDL"},"strain_display":{"value":"USA/OQ348875/2022-06-27"},"date":{"value":"2022-06-27"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T6976-","G53144A","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","C145153T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C165730T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG071":["S432F"]},"labels":{"aa":"OPG071: S432F"}}},{"name":"OQ339209","node_attrs":{"div":2,"accession":"OQ339209","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI690"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ339209/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","G103240A","G150551-","A150563-","T150564-","G150565-","A150566-","T150567-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C156437T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG044":["K147-"]},"labels":{"aa":"OPG044: K147-"}}},{"name":"OQ320520","node_attrs":{"div":0,"accession":"OQ320520","author":{"author":"Gigante,C.,Ostadkar,R.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Weigand,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,X.,Li,Y.","value":"Gigante,C.,Ostadkar,R.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Weigand,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,X.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_MN0008"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ320520/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ320449","node_attrs":{"div":3,"accession":"OQ320449","author":{"author":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y.","value":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_DC0020"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ320449/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G6619A","C99831T","C142957T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ557951","node_attrs":{"div":5,"accession":"OQ557951","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_TX0003"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ557951/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","C19610T","G108050A","T133102-","C135024T","C135225T","C156627T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-196615A"]}}},{"name":"OQ547776","node_attrs":{"div":0,"accession":"OQ547776","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI749"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ547776/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OQ547894","node_attrs":{"div":0,"accession":"OQ547894","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000169/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDPH, VRDL"},"strain_display":{"value":"USA/OQ547894/2023-01-09"},"date":{"value":"2023-01-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T6976-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ503763","node_attrs":{"div":1,"accession":"OQ503763","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-090794/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OQ503763/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G72069A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR086938","node_attrs":{"div":0,"accession":"OR086938","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Horemans,M.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Horemans,M.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_129/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR086938/2022-06-29"},"date":{"value":"2022-06-29"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035730","node_attrs":{"div":4,"accession":"OR035730","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_124"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035730/2022-09-20"},"date":{"value":"2022-09-20"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C12298T","C32853T","G35385A","C169036T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG049":["G100E"]},"labels":{"aa":"OPG049: G100E"}}},{"name":"OR035729","node_attrs":{"div":2,"accession":"OR035729","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_123"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035729/2022-09-20"},"date":{"value":"2022-09-20"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C19277T","C166803T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG192":["P25S"]},"labels":{"aa":"OPG192: P25S"}}},{"name":"OR035725","node_attrs":{"div":1,"accession":"OR035725","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_119"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035725/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-","C137999T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG154":["E18K"]},"labels":{"aa":"OPG154: E18K"}}},{"name":"OR035720","node_attrs":{"div":1,"accession":"OR035720","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_114"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035720/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C8597T","T133101-","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035693","node_attrs":{"div":0,"accession":"OR035693","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_87"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035693/2022-08-09"},"date":{"value":"2022-08-09"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035687","node_attrs":{"div":1,"accession":"OR035687","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_81"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035687/2022-08-09"},"date":{"value":"2022-08-09"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T98627C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG118":["V61A"]},"labels":{"aa":"OPG118: V61A"}}},{"name":"OR035684","node_attrs":{"div":0,"accession":"OR035684","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_78"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035684/2022-06-29"},"date":{"value":"2022-06-29"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035681","node_attrs":{"div":0,"accession":"OR035681","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_75"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035681/2022-06-03"},"date":{"value":"2022-06-03"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-"]}}},{"name":"OR035682","node_attrs":{"div":0,"accession":"OR035682","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_76"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035682/2022-06-07"},"date":{"value":"2022-06-07"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035683","node_attrs":{"div":0,"accession":"OR035683","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_77"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035683/2022-06-13"},"date":{"value":"2022-06-13"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035656","node_attrs":{"div":1,"accession":"OR035656","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_50"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035656/2022-05-31"},"date":{"value":"2022-05-31"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","C173614T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035649","node_attrs":{"div":0,"accession":"OR035649","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_43"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035649/2022-08-02"},"date":{"value":"2022-08-02"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR030940","node_attrs":{"div":1,"accession":"OR030940","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_29"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR030940/2022-07-15"},"date":{"value":"2022-07-15"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C82511T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR030935","node_attrs":{"div":2,"accession":"OR030935","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_24"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR030935/2022-07-19"},"date":{"value":"2022-07-19"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C94839T","C131367T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG151":["S815F"]},"labels":{"aa":"OPG151: S815F"}}},{"name":"OR030933","node_attrs":{"div":1,"accession":"OR030933","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_22"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR030933/2022-07-19"},"date":{"value":"2022-07-19"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","C170121T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR030925","node_attrs":{"div":1,"accession":"OR030925","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_7"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR030925/2022-06-09"},"date":{"value":"2022-06-09"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["A28532-","T76087-","T80849-","T133639-","A138474-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C187959T","-196615A"],"OPG044":["M148-"]},"labels":{"aa":"OPG044: M148-"}}},{"name":"OR030923","node_attrs":{"div":0,"accession":"OR030923","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_12"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR030923/2022-06-29"},"date":{"value":"2022-06-29"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T606-","A26090-","T26091-","T76087-","T80849-","A89106-","T133101-","T133102-","T155424-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OQ918696","node_attrs":{"div":6,"accession":"OQ918696","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00485/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ918696/2023-03-11"},"date":{"value":"2023-03-11"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G30285A","G37487A","C71193T","G119839A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C161690T","C177865T","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T179244-"],"OPG047":["P304S"],"OPG137":["E80K"],"OPG188":["S32F"],"OPG205":["S737F"]},"labels":{"aa":"OPG047: P304S; OPG137: E80K; OPG188: S32F; OPG205: S737F"}}},{"name":"OQ721951","node_attrs":{"div":3,"accession":"OQ721951","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Taiwan/110-122438/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"strain_display":{"value":"Taiwan/OQ721951/2023-03-XX"},"date":{"value":"2023-03-XX"},"country":{"value":"Taiwan"}},"branch_attrs":{"mutations":{"nuc":["T133092-","T133093-","T133094-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T149983A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G160358A","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A184479G","G193496T","A193498T","A193748G","T194019G","T194021A","G194086A"],"OPG003_dup":["K298N","E299V","C473G","R495K"],"OPG176":["S59T"],"OPG210":["R1042G"]},"labels":{"aa":"OPG003_dup: K298N, E299V, C473G, R495K; OPG176: S59T; OPG210: R1042G"}}},{"name":"OQ672580","node_attrs":{"div":9,"accession":"OQ672580","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Taiwan/110-093354/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"strain_display":{"value":"Taiwan/OQ672580/2023-03-XX"},"date":{"value":"2023-03-XX"},"country":{"value":"Taiwan"}},"branch_attrs":{"mutations":{"nuc":["T4795C","C39503G","G43620A","A44076G","G45563A","T69121C","T80764C","A130204G","A143123G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG057":["K231N"],"OPG064":["F608S"],"OPG087":["Y89H"],"OPG104":["N86D"],"OPG164":["T116A"]},"labels":{"aa":"OPG057: K231N; OPG064: F608S; OPG087: Y89H; OPG104: N86D; OPG164: T116A"}}},{"name":"OQ627926","node_attrs":{"div":0,"accession":"OQ627926","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"INMI-22932022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"strain_display":{"value":"Italy/OQ627926/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OQ581849","node_attrs":{"div":2,"accession":"OQ581849","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0007b/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"strain_display":{"value":"Spain/OQ581849/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["A52777C","C150418T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T169409C","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG071":["Y554*"]},"labels":{"aa":"OPG071: Y554*"}}},{"name":"OQ581848","node_attrs":{"div":1,"accession":"OQ581848","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0006b/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"strain_display":{"value":"Spain/OQ581848/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["C133168-","T133169-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C174264T","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ570421","node_attrs":{"div":2,"accession":"OQ570421","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"INMI-22872022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"strain_display":{"value":"Italy/OQ570421/2022-08-22"},"date":{"value":"2022-08-22"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["C106275T","G111562A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG130":["S114F"]},"labels":{"aa":"OPG130: S114F"}}},{"name":"OR449703","node_attrs":{"div":0,"accession":"OR449703","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI989"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR449703/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"OR449638","node_attrs":{"div":0,"accession":"OR449638","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI924"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR449638/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150551-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"OR353584","node_attrs":{"div":1,"accession":"OR353584","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MN-MDH-MPXV_0074"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Minnesota Department of Health, Public Health Laboratory"},"strain_display":{"value":"USA/OR353584/2022-09-15"},"date":{"value":"2022-09-15"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","T129642G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T196756-","G196757-","T196758-"],"OPG151":["L240*"]},"labels":{"aa":"OPG151: L240*"}}},{"name":"OR264462","node_attrs":{"div":0,"accession":"OR264462","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"8_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264462/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OR264461","node_attrs":{"div":0,"accession":"OR264461","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"8_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264461/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264418","node_attrs":{"div":0,"accession":"OR264418","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"44_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264418/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OR264419","node_attrs":{"div":0,"accession":"OR264419","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"44_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264419/2022-07-10"},"date":{"value":"2022-07-10"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OR264409","node_attrs":{"div":1,"accession":"OR264409","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"39_L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264409/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["C66718T","T179244-"],"OPG084":["S666L"]},"labels":{"aa":"OPG084: S666L"}}},{"name":"OR264387","node_attrs":{"div":0,"accession":"OR264387","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"28_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264387/2022-06-23"},"date":{"value":"2022-06-23"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264384","node_attrs":{"div":6,"accession":"OR264384","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"27_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264384/2022-08-14"},"date":{"value":"2022-08-14"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","G29641A","A50415G","T76084-","T76085-","T80846-","T80847-","G109811A","T121121-","C146721T","A152675-","A152676-","G176229A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","G188299A"],"OPG044":["K147-"],"OPG046":["S30L"],"OPG069":["S144G"],"OPG170":["E20K"],"OPG205":["E192K"]},"labels":{"aa":"OPG044: K147-; OPG046: S30L; OPG069: S144G; OPG170: E20K; OPG205: E192K"}}},{"name":"OR095066","node_attrs":{"div":0,"accession":"OR095066","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_248/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR095066/2022-08-16"},"date":{"value":"2022-08-16"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR086978","node_attrs":{"div":0,"accession":"OR086978","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_169/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR086978/2022-07-27"},"date":{"value":"2022-07-27"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR086963","node_attrs":{"div":0,"accession":"OR086963","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_154/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR086963/2022-07-15"},"date":{"value":"2022-07-15"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR086969","node_attrs":{"div":0,"accession":"OR086969","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_160/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR086969/2022-07-27"},"date":{"value":"2022-07-27"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C196750-","T196751-","A196752-"]}}},{"name":"OR086948","node_attrs":{"div":0,"accession":"OR086948","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_139/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR086948/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OX336004","node_attrs":{"div":1,"accession":"OX336004","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX336004/2022-08-26"},"date":{"value":"2022-08-26"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{"nuc":["T606-","C94836T","T133100-","T133101-","T133102-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"]}}},{"name":"OX261748","node_attrs":{"div":0,"accession":"OX261748","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX261748/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{"nuc":["T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"]}}},{"name":"OR759206","node_attrs":{"div":4,"accession":"OR759206","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL118/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759206/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["T606-","C25172T","C67289T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G164327A","G164910A","A196614-"],"OPG040":["D103N"],"OPG085":["E415K"],"OPG189":["G332E"]},"labels":{"aa":"OPG040: D103N; OPG085: E415K; OPG189: G332E"}}},{"name":"OR759163","node_attrs":{"div":0,"accession":"OR759163","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL072/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759163/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR759159","node_attrs":{"div":1,"accession":"OR759159","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL071/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759159/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C20143T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG035":["E88K"]},"labels":{"aa":"OPG035: E88K"}}},{"name":"OR759145","node_attrs":{"div":1,"accession":"OR759145","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL054/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759145/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C171732T"],"OPG199":["L249F"]},"labels":{"aa":"OPG199: L249F"}}},{"name":"OR499950","node_attrs":{"div":8,"accession":"OR499950","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00493/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499950/2023-04-24"},"date":{"value":"2023-04-24"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C21494T","C69560T","C80874T","C86342T","C137855T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C182578T","C188161T","C189998T"],"OPG037":["D314N"],"OPG088":["V102M"],"OPG104":["S49N"],"OPG108":["D240N"],"OPG154":["E66K"],"OPG210":["S408L"]},"labels":{"aa":"OPG037: D314N; OPG088: V102M; OPG104: S49N; OPG108: D240N; OPG154: E66K; OPG210: S408L"}}},{"name":"OR488002","node_attrs":{"div":2,"accession":"OR488002","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0684/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR488002/2022-05-31"},"date":{"value":"2022-05-31"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C132153T","C132940T","C133227T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG151":["S1077L"]},"labels":{"aa":"OPG151: S1077L"}}},{"name":"OR464218","node_attrs":{"div":2,"accession":"OR464218","author":{"author":"Gigante,C.,Johnson,S.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Riner,D.,Li,Y.","value":"Gigante,C.,Johnson,S.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Riner,D.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_MI0013"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OR464218/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C8222T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","G186177A"],"OPG210":["E1608K"]},"labels":{"aa":"OPG210: E1608K"}}},{"name":"OR464192","node_attrs":{"div":6,"accession":"OR464192","author":{"author":"Gigante,C.,Pettit,D.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Deutsch-Feldman,M.,Li,Y.","value":"Gigante,C.,Pettit,D.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Deutsch-Feldman,M.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_NC0016"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OR464192/2022-12-XX"},"date":{"value":"2022-12-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T606-","C14091T","G16956A","G56721A","C94427T","G141759A","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","C184829T","A196614-"],"OPG025":["E393K"],"OPG114":["E81K"]},"labels":{"aa":"OPG025: E393K; OPG114: E81K"}}},{"name":"NODE_0000042","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C127220T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG148":["S412L"],"OPG149":["Q9*"]},"labels":{"aa":"OPG148: S412L; OPG149: Q9*"}},"children":[{"name":"ON585036","node_attrs":{"div":2,"accession":"ON585036","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0010/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"strain_display":{"value":"Portugal/ON585036/2022-05-15"},"date":{"value":"2022-05-15"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C144527T","A188351-"],"OPG166":["P44S"]},"labels":{"aa":"OPG166: P44S"}}},{"name":"OP414370","node_attrs":{"div":1,"accession":"OP414370","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0341/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414370/2022-05-27"},"date":{"value":"2022-05-27"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C663-","A664-","A196619-","T196620-"]}}}]},{"name":"NODE_0000043","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133102-","T168120C","-179207A"],"OPG193":["F263L"]},"labels":{"aa":"OPG193: F263L"}},"children":[{"name":"OP144216","node_attrs":{"div":1,"accession":"OP144216","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/ITM_pt_07/Belgium/30-May-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OP144216/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["A133165-","A133166-","T133167-","C133168-","T133169-","T133170-","T133171-","C133172-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T140113-","A140114-","T140115-","A140116-","A140117-","T140122-","A140123-","T140124-","A140125-","A140126-","C140127-","A140128-","A140129-","T140130-","T140131-","A140132-","T140133-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","A140143-","A140144-","T140145-","T140146-","G140147-","T140148-","T140149-","A140150-","T140151-","A140152-","A140153-","T140154-","A140155-","-179240T","-179241A","-179242T","-179243A"],"OPG159":["Y116-","N117-","Y119-","N120-","N121-","Y122-","N123-","N124-","Y125-","N126-","C127-","Y128-","N129-","N130-"]},"labels":{"aa":"OPG159: Y116-, N117-, Y119-, N120-, N121-, Y122-, N123-, N124-, Y125-, N126-, C127-, Y128-, N129-, N130-"}}},{"name":"OP144215","node_attrs":{"div":1,"accession":"OP144215","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/ITM_pt_05/Belgium/30-May-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OP144215/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T179244-","C179245-","G179246-","T179247-","T179248-"]}}}]},{"name":"NODE_0000044","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A28532-","T133098-","T133099-","T133100-","T133101-","T133102-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","C179091-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188252T","A196613-","A196614-"],"OPG044":["M148-"]},"labels":{"aa":"OPG044: M148-"}},"children":[{"name":"OP133005","node_attrs":{"div":1,"accession":"OP133005","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1531848/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP133005/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{"nuc":["A179077-","A179090-","A179092-","T179093-","G197058T","C197173G"]}}},{"name":"OP133004","node_attrs":{"div":1,"accession":"OP133004","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1533374/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP133004/2022-07-11"},"date":{"value":"2022-07-11"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{"nuc":["A322G","T450C","-179091T"]}}}]},{"name":"NODE_0000045","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C144546T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"],"OPG166":["S50F"]},"labels":{"aa":"OPG166: S50F"}},"children":[{"name":"OP019275","node_attrs":{"div":3,"accession":"OP019275","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1525179/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP019275/2022-06-10"},"date":{"value":"2022-06-10"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","A107070C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G190319A","-196616A","-196617A"]}}},{"name":"OR473631","node_attrs":{"div":1,"accession":"OR473631","author":{"author":"Kwasiborski,A.,Hourdel,V.,Baliere,C.,Hoinard,D.,Grassin,Q.,Feher,M.,De La Porte Des Vaux,C.,Cresta,M.,Vanhomwegen,J.,Manuguerra,J.-C.,Batejat,C.,Caro,V.","value":"Kwasiborski,A.,Hourdel,V.,Baliere,C.,Hoinard,D.,Grassin,Q.,Feher,M.,De La Porte Des Vaux,C.,Cresta,M.,Vanhomwegen,J.,Manuguerra,J.-C.,Batejat,C.,Caro,V."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"CIBU-220031"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Insitut Pasteur, Environment and Infectious Risks Unit"},"strain_display":{"value":"France/OR473631/2022-06-03"},"date":{"value":"2022-06-03"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A"]}}}]},{"name":"NODE_0000046","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C4629T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","G192581A"]}},"children":[{"name":"ON622713","node_attrs":{"div":1,"accession":"ON622713","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/UZ_REGA_2/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Microbiology, Immunology & Transplantation, KU Leuven, Rega Institute, Belgium"},"strain_display":{"value":"Belgium/ON622713/2022-05-22"},"date":{"value":"2022-05-22"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ159044","node_attrs":{"div":6,"accession":"OQ159044","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI649"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ159044/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C75807T","C110546T","G141123A","G157626A","C171794T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG096":["A74V"],"OPG161":["E8K"]},"labels":{"aa":"OPG096: A74V; OPG161: E8K"}}}]},{"name":"NODE_0000047","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C96773T","C109432T","C142356T"],"OPG117":["S242L"],"OPG129":["D525N"],"OPG163":["S52F"]},"labels":{"aa":"OPG117: S242L; OPG129: D525N; OPG163: S52F"}},"children":[{"name":"OP341487","node_attrs":{"div":4,"accession":"OP341487","author":{"author":"Welkers,M.,Jonges,M.,de Regt,M.,Ooijevaar,R.,Wagemakers,A.","value":"Welkers,M.,Jonges,M.,de Regt,M.,Ooijevaar,R.,Wagemakers,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Netherlands/NH-AUMC-0060/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention"},"strain_display":{"value":"Netherlands/OP341487/2022-08-05"},"date":{"value":"2022-08-05"},"country":{"value":"Netherlands"}},"branch_attrs":{"mutations":{"nuc":["C114985T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG133":["D238N"]},"labels":{"aa":"OPG133: D238N"}}},{"name":"OP245310","node_attrs":{"div":3,"accession":"OP245310","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/PT0053/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP245310/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}}]},{"name":"NODE_0000048","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G16110A","G51378A","C89030T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G181082A"],"OPG109":["V140I"],"OPG209":["D189N"]},"labels":{"aa":"OPG109: V140I; OPG209: D189N"}},"children":[{"name":"OP328312","node_attrs":{"div":4,"accession":"OP328312","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-087564/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP328312/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR433615","node_attrs":{"div":4,"accession":"OR433615","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-080214/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR433615/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000049","node_attrs":{"div":1,"lineage":{"value":"B.1.13"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G175093A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG204":["D188N"]},"labels":{"aa":"OPG204: D188N","clade":"B.1.13"}},"children":[{"name":"OP257254","node_attrs":{"div":2,"accession":"OP257254","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.13"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/OH-UW-073812/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP257254/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C132520T"]}}},{"name":"OP536663","node_attrs":{"div":3,"accession":"OP536663","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"lineage":{"value":"B.1.13"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-USA-IL-IDPH-002"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"strain_display":{"value":"USA/OP536663/2022-08-04"},"date":{"value":"2022-08-04"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G119424A","G125452A","-196615A","-196616A","-196617A"],"OPG136":["S55L"],"OPG146":["S63L"]},"labels":{"aa":"OPG136: S55L; OPG146: S63L"}}}]},{"name":"NODE_0000050","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C23567T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP205109","node_attrs":{"div":2,"accession":"OP205109","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000146"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205109/2022-06-13"},"date":{"value":"2022-06-13"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C118683T"],"OPG136":["R302K"]},"labels":{"aa":"OPG136: R302K"}}},{"name":"OP415212","node_attrs":{"div":4,"accession":"OP415212","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_UbfBKN_9000238"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415212/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C67289T","G67527A","G77052A"],"OPG085":["E415K"]},"labels":{"aa":"OPG085: E415K"}}}]},{"name":"NODE_0000051","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C102355T","C113923T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG121":["S189L"],"OPG133":["D592N"]},"labels":{"aa":"OPG121: S189L; OPG133: D592N"}},"children":[{"name":"OP422343","node_attrs":{"div":2,"accession":"OP422343","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1540386/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP422343/2022-08-08"},"date":{"value":"2022-08-08"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{}}},{"name":"OP422340","node_attrs":{"div":2,"accession":"OP422340","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1533948/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP422340/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000052","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T12827C","T12833A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG023":["D23V","N25S"]},"labels":{"aa":"OPG023: D23V, N25S"}},"children":[{"name":"OP440550","node_attrs":{"div":4,"accession":"OP440550","author":{"author":"Hemarajata,P.,Green,N.M.","value":"Hemarajata,P.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00035/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP440550/2022-08-13"},"date":{"value":"2022-08-13"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C1735T","T149447C","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G195475A","-196615A"]}}},{"name":"OP414329","node_attrs":{"div":3,"accession":"OP414329","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0295/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414329/2022-06-08"},"date":{"value":"2022-06-08"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C27303T"],"OPG043":["G218E"]},"labels":{"aa":"OPG043: G218E"}}}]},{"name":"NODE_0000053","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C170573T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}},"children":[{"name":"OP415248","node_attrs":{"div":3,"accession":"OP415248","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_XJRG9b_9000293"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415248/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["G148403A","G148615A"],"OPG174":["L261F"]},"labels":{"aa":"OPG174: L261F"}}},{"name":"OP605567","node_attrs":{"div":3,"accession":"OP605567","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-25-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605567/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["C71938T","G73939A","T196886-","T196887-","T196888-"],"OPG092":["R337K"],"OPG094":["D54N"]},"labels":{"aa":"OPG092: R337K; OPG094: D54N"}}}]},{"name":"NODE_0000054","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G59905A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG080":["S705F"]},"labels":{"aa":"OPG080: S705F"}},"children":[{"name":"OP615276","node_attrs":{"div":4,"accession":"OP615276","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00203/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP615276/2022-07-19"},"date":{"value":"2022-07-19"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G131350A","C135330T","G150732A"]}}},{"name":"OP722497","node_attrs":{"div":2,"accession":"OP722497","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00238/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP722497/2022-07-21"},"date":{"value":"2022-07-21"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C165424T"]}}}]},{"name":"NODE_0000055","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A33-","C8385T","A86934G","G91904A","T133101-","T133102-","A151508-","A151509-","T151510-","T151512-","T151514-","T151517-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196751-","A196752-"]}},"children":[{"name":"OP605584","node_attrs":{"div":4,"accession":"OP605584","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-43-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605584/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["-607T","T33995A","-133101T","-133102T","-151508A","-151509A","-151510T","-151512T","-151514T","-151517T","-151523A","-151524T","-196751T","-196752A"],"OPG052":["M1L"]},"labels":{"aa":"OPG052: M1L"}}},{"name":"OR087013","node_attrs":{"div":3,"accession":"OR087013","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_204/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR087013/2022-08-08"},"date":{"value":"2022-08-08"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G151511-","C151513-","C151515-","G151516-","G151518-","G151519-","G151520-","G151521-","C151522-","C196750-"]}}}]},{"name":"NODE_0000056","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G84579A","A87268G","G115865A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG105":["D1152N"],"OPG109":["V727A"],"OPG134":["R39K"]},"labels":{"aa":"OPG105: D1152N; OPG109: V727A; OPG134: R39K"}},"children":[{"name":"OP588277","node_attrs":{"div":3,"accession":"OP588277","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI414"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP588277/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-179189A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"]}}},{"name":"OP689663","node_attrs":{"div":3,"accession":"OP689663","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI510"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP689663/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000057","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C55859T","C93755T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG074":["V423I"]},"labels":{"aa":"OPG074: V423I"}},"children":[{"name":"OP555660","node_attrs":{"div":2,"accession":"OP555660","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0593/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555660/2022-09-14"},"date":{"value":"2022-09-14"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OQ451901","node_attrs":{"div":6,"accession":"OQ451901","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI716"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ451901/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-607T","C2315T","G21250A","G40586A","G146821A","G160267A","G194895A"],"OPG002":["G146E"],"OPG002_dup":["G146E"],"OPG037":["S395F"]},"labels":{"aa":"OPG002: G146E; OPG002_dup: G146E; OPG037: S395F"}}}]},{"name":"NODE_0000058","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C15480T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}},"children":[{"name":"OP555642","node_attrs":{"div":2,"accession":"OP555642","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0571/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555642/2022-09-05"},"date":{"value":"2022-09-05"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["A19385T"],"OPG034":["F207L"]},"labels":{"aa":"OPG034: F207L"}}},{"name":"OP555630","node_attrs":{"div":2,"accession":"OP555630","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0559/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555630/2022-08-30"},"date":{"value":"2022-08-30"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G102204A","A136543-","T136544-","C136545-","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-"],"OPG121":["E139K"],"OPG153":["D382-","D383-","D384-","D385-"]},"labels":{"aa":"OPG121: E139K; OPG153: D382-, D383-, D384-, D385-"}}}]},{"name":"NODE_0000059","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G98456A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG118":["G4E"]},"labels":{"aa":"OPG118: G4E"}},"children":[{"name":"OP881941","node_attrs":{"div":9,"accession":"OP881941","author":{"author":"Gigante,C.,Ingram,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Geeter,E.,Li,Y.","value":"Gigante,C.,Ingram,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Geeter,E.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_AL0001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP881941/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G17735A","C25644T","G74526A","T97911C","C103258T","G141521A","G157338A","G157752A"],"OPG123":["D605N"]},"labels":{"aa":"OPG123: D605N"}}},{"name":"OR030924","node_attrs":{"div":4,"accession":"OR030924","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_13"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR030924/2022-06-29"},"date":{"value":"2022-06-29"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T606-","G18442A","G26858A","A28532-","T76087-","T80849-","A89106-","T155424-","G170981A"],"OPG044":["M148-"]},"labels":{"aa":"OPG044: M148-"}}}]},{"name":"NODE_0000060","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C43487T","C71729T","C101983T"],"OPG063":["D68N"],"OPG121":["S65L"]},"labels":{"aa":"OPG063: D68N; OPG121: S65L"}},"children":[{"name":"OQ503837","node_attrs":{"div":3,"accession":"OQ503837","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00460/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ503837/2023-01-23"},"date":{"value":"2023-01-23"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OR209311","node_attrs":{"div":3,"accession":"OR209311","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_TX0053"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OR209311/2023-01-XX"},"date":{"value":"2023-01-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000061","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C111391T","C119654T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","C152191T","A173314-","T173315-","A173316-","T173317-","C176178T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-"],"OPG130":["C171Y"],"OPG137":["S18L"],"OPG205":["H175Y"]},"labels":{"aa":"OPG130: C171Y; OPG137: S18L; OPG205: H175Y"}},"children":[{"name":"OQ973327","node_attrs":{"div":4,"accession":"OQ973327","author":{"author":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L.","value":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"case1_skin"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ973327/2022-09-06"},"date":{"value":"2022-09-06"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G173595-","G173596-","T173597-","T173598-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","A180535-","A180536-","T180537-","A180538-","G180539-","C180540-","G180541-","T180542-","A180543-","T180544-","C180545-","T180546-","T180547-","A180548-"]}}},{"name":"OQ973326","node_attrs":{"div":4,"accession":"OQ973326","author":{"author":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L.","value":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"case1_air"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ973326/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G2615-","A2616-","T2617-","A2618-","G2619-","A2620-","C2621-","A2622-","A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","T2653-","T2654-","T2655-","A2656-","C2657-","A2658-","C2659-","T2660-","T2661-","A194549-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","A196613-","A196614-"],"OPG002":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-"],"OPG002_dup":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-"]},"labels":{"aa":"OPG002: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-; OPG002_dup: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-"}}}]},{"name":"NODE_0000062","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C28887T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG045":["E126K"]},"labels":{"aa":"OPG045: E126K"}},"children":[{"name":"OX336038","node_attrs":{"div":1,"accession":"OX336038","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX336038/2022-08-31"},"date":{"value":"2022-08-31"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{}}},{"name":"OX291694","node_attrs":{"div":5,"accession":"OX291694","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX291694/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{"nuc":["C15311T","C54262T","G81015T","G141131A"],"OPG104":["T2K"]},"labels":{"aa":"OPG104: T2K"}}}]},{"name":"NODE_0000063","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G67955A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G184141A","A196614-"],"OPG085":["P193S"],"OPG210":["G929D"]},"labels":{"aa":"OPG085: P193S; OPG210: G929D"}},"children":[{"name":"OX291780","node_attrs":{"div":2,"accession":"OX291780","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX291780/2022-07-25"},"date":{"value":"2022-07-25"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{"nuc":["A173316-","T173317-"]}}},{"name":"OX291676","node_attrs":{"div":3,"accession":"OX291676","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX291676/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{"nuc":["G14590A","T133102-"]}}}]},{"name":"NODE_0000064","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G57076A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG074":["S17L"]},"labels":{"aa":"OPG074: S17L"}},"children":[{"name":"OX291435","node_attrs":{"div":1,"accession":"OX291435","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX291435/2022-07-25"},"date":{"value":"2022-07-25"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{"nuc":["T164536-","T164537-","G164538-","A164539-","A164540-","A164541-","A164542-","T164543-","T164544-","A164545-","T164546-","G164547-","A164548-","T164549-","A164550-","C164551-","C164552-","A164553-","T164554-","C164555-","T164556-","A173314-","T173315-","A173316-","T173317-"],"OPG189":["L402-","K403-","I404-","M405-","I406-","P407-","S408-"]},"labels":{"aa":"OPG189: L402-, K403-, I404-, M405-, I406-, P407-, S408-"}}},{"name":"OX291424","node_attrs":{"div":1,"accession":"OX291424","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX291424/2022-07-25"},"date":{"value":"2022-07-25"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000065","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C118421T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG136":["M389I"]},"labels":{"aa":"OPG136: M389I"}},"children":[{"name":"OP120938","node_attrs":{"div":2,"accession":"OP120938","author":{"author":"Aja-Macaya,P.,Rumbo-Feal,S.,Poza,M.,Canizares,A.,Vallejo,J.A.,Bou,G.","value":"Aja-Macaya,P.,Rumbo-Feal,S.,Poza,M.,Canizares,A.,Vallejo,J.A.,Bou,G."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MP03CHUAC"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Biomedical research institute (INIBIC), Microbiology"},"strain_display":{"value":"Spain/OP120938/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["C142607T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG163":["H136Y"]},"labels":{"aa":"OPG163: H136Y"}}},{"name":"NODE_0000066","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G133806A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}},"children":[{"name":"OP536771","node_attrs":{"div":4,"accession":"OP536771","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000393"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536771/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-607T","G63147A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C160426T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OR264382","node_attrs":{"div":2,"accession":"OR264382","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"26_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264382/2022-07-19"},"date":{"value":"2022-07-19"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000068","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C73609T","C113740T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG093":["S211L"],"OPG133":["D653N"]},"labels":{"aa":"OPG093: S211L; OPG133: D653N"}},"children":[{"name":"OP626126","node_attrs":{"div":2,"accession":"OP626126","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI488"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP626126/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"OP594188","node_attrs":{"div":3,"accession":"OP594188","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI424"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP594188/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G8068A"]}}},{"name":"OQ773481","node_attrs":{"div":2,"accession":"OQ773481","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI862"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ773481/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150564-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}}]},{"name":"NODE_0000069","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G21655A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG037":["S260L"]},"labels":{"aa":"OPG037: S260L"}},"children":[{"name":"OP837354","node_attrs":{"div":1,"accession":"OP837354","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI592"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP837354/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"OP764629","node_attrs":{"div":1,"accession":"OP764629","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI571"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP764629/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"OQ451900","node_attrs":{"div":1,"accession":"OQ451900","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI715"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ451900/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-607T"]}}}]},{"name":"NODE_0000070","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","G145790A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OQ348891","node_attrs":{"div":2,"accession":"OQ348891","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000144/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDPH, VRDL"},"strain_display":{"value":"USA/OQ348891/2022-06-25"},"date":{"value":"2022-06-25"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T6976-","C117143T"]}}},{"name":"NODE_0000071","node_attrs":{"div":5,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G1512A","G12099A","C143551T","G160358A","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","C195698T"],"OPG001":["Q22*"],"OPG001_dup":["Q22*"],"OPG023":["R268*"]},"labels":{"aa":"OPG001: Q22*; OPG001_dup: Q22*; OPG023: R268*"}},"children":[{"name":"OQ503818","node_attrs":{"div":8,"accession":"OQ503818","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00425/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ503818/2022-12-03"},"date":{"value":"2022-12-03"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G44107A","G107064A","T133177-","C133178-","T133179-","T133180-","T133181-","C133182-","T133183-","C133184-","A133185-","A133186-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C188361T"]}}},{"name":"OQ603483","node_attrs":{"div":5,"accession":"OQ603483","author":{"author":"Haw,M.,Kath,C.,Espinosa,A.,O'Neil,R.,Hacker,J.","value":"Haw,M.,Kath,C.,Espinosa,A.,O'Neil,R.,Hacker,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000214/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDPH, VRDL"},"strain_display":{"value":"USA/OQ603483/2023-01-31"},"date":{"value":"2023-01-31"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C942T","G196268A"],"OPG001":["E212K"],"OPG001_dup":["E212K"]},"labels":{"aa":"OPG001: E212K; OPG001_dup: E212K"}}}]}]},{"name":"NODE_0000072","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G2146A","C39044T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T187876C","C195064T"]}},"children":[{"name":"OQ503829","node_attrs":{"div":6,"accession":"OQ503829","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00406/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ503829/2023-01-09"},"date":{"value":"2023-01-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C2749T","G112552A","C167231T","G194461A"],"OPG002":["M1I"],"OPG002_dup":["M1I"],"OPG132":["S330L"]},"labels":{"aa":"OPG002: M1I; OPG002_dup: M1I; OPG132: S330L"}}},{"name":"NODE_0000073","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A24345G","T170904-"]}},"children":[{"name":"OQ644777","node_attrs":{"div":4,"accession":"OQ644777","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00471/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ644777/2023-02-13"},"date":{"value":"2023-02-13"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ644776","node_attrs":{"div":4,"accession":"OQ644776","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00470/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ644776/2023-02-13"},"date":{"value":"2023-02-13"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000074","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G162623A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG188":["R343K"]},"labels":{"aa":"OPG188: R343K"}},"children":[{"name":"OR087002","node_attrs":{"div":1,"accession":"OR087002","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_193/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR087002/2022-08-03"},"date":{"value":"2022-08-03"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-"]}}},{"name":"NODE_0000075","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C110147T"]}},"children":[{"name":"OR035731","node_attrs":{"div":3,"accession":"OR035731","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_125"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035731/2022-09-20"},"date":{"value":"2022-09-20"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G61361A"]}}},{"name":"OR035708","node_attrs":{"div":3,"accession":"OR035708","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_102"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035708/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C60081T","T196712-","A196713-","T196714-"]}}}]}]},{"name":"NODE_0000076","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","A41654-","A41655-","T41656-","A41657-","C41658-","T41659-","A41660-","A41661-","T41662-","T41663-","T41664-","G41665-","T41666-","T41667-","T41668-","T41669-","A41670-","C41671-","T41672-","C41673-","T41674-","A41675-","T41676-","A41677-","C118161T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG061":["V72-","K73-","Q74-","I75-","S76-","I77-"],"OPG136":["R476Q"]},"labels":{"aa":"OPG061: V72-, K73-, Q74-, I75-, S76-, I77-; OPG136: R476Q"}},"children":[{"name":"OR035716","node_attrs":{"div":6,"accession":"OR035716","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_110"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035716/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T607-","G36963A","-41654A","-41655A","-41656T","-41657A","-41658C","-41659T","-41660A","-41661A","-41662T","-41663T","-41664T","-41665G","-41666T","-41667T","-41668T","-41669T","-41670A","-41671C","-41672T","-41673C","-41674T","-41675A","-41676T","-41677A","G48024A","C109810T","G149818A","C170573T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","T196712-","A196713-","T196714-"],"OPG055":["R41C"],"OPG061":["-72V","-73K","-74Q","-75I","-76S","-77I"],"OPG129":["D399N"],"OPG176":["D4N"],"OPG198":["S179L"]},"labels":{"aa":"OPG055: R41C; OPG061: -72V, -73K, -74Q, -75I, -76S, -77I; OPG129: D399N; OPG176: D4N; OPG198: S179L"}}},{"name":"OR264421","node_attrs":{"div":1,"accession":"OR264421","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"46_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264421/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"OPG061":["R71-"]},"labels":{"aa":"OPG061: R71-"}}},{"name":"OR264423","node_attrs":{"div":1,"accession":"OR264423","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"46_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264423/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"OPG061":["S78-"]},"labels":{"aa":"OPG061: S78-"}}}]},{"name":"NODE_0000077","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133100-","T133101-","T133102-","C147965T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG172":["S180F"]},"labels":{"aa":"OPG172: S180F"}},"children":[{"name":"OR095046","node_attrs":{"div":1,"accession":"OR095046","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Van Holm,B.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Van Holm,B.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_228/Belgium/2022'"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR095046/2022-08-12"},"date":{"value":"2022-08-12"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C196881-","G196882-","T196883-"]}}},{"name":"NODE_0000078","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C28168T","T133097-","T133098-","T133099-","A173314-","T173315-","A173316-","T173317-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","C179470T","A196614-"],"OPG208":["P69S"]},"labels":{"aa":"OPG208: P69S"}},"children":[{"name":"OQ973328","node_attrs":{"div":3,"accession":"OQ973328","author":{"author":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L.","value":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"case6_air"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ973328/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G2615-","A2616-","T2617-","A2618-","G2619-","A2620-","C2621-","A2622-","A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","T2653-","T2654-","T2655-","A2656-","C2657-","A2658-","C2659-","T2660-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","C194595-"],"OPG002":["C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-"],"OPG002_dup":["C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-"]},"labels":{"aa":"OPG002: C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-; OPG002_dup: C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-"}}},{"name":"OQ973329","node_attrs":{"div":3,"accession":"OQ973329","author":{"author":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L.","value":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"case6_skin"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ973329/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C173474-","G173475-","A173476-","C173477-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","A180535-","A180536-","T180537-","A180538-","G180539-","C180540-","G180541-","T180542-","A180543-","T180544-","C180545-","T180546-","T180547-","A180548-"]}}}]}]},{"name":"NODE_0000079","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C130606T"]}},"children":[{"name":"OR759155","node_attrs":{"div":1,"accession":"OR759155","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL065/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759155/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000080","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C45203T","C88917T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}},"children":[{"name":"OQ627927","node_attrs":{"div":3,"accession":"OQ627927","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"INMI-18982022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"strain_display":{"value":"Italy/OQ627927/2022-08-16"},"date":{"value":"2022-08-16"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{}}},{"name":"OQ570420","node_attrs":{"div":3,"accession":"OQ570420","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"INMI-14732022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"strain_display":{"value":"Italy/OQ570420/2022-08-11"},"date":{"value":"2022-08-11"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000081","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","C168943T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OR095049","node_attrs":{"div":1,"accession":"OR095049","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_231/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR095049/2022-08-12"},"date":{"value":"2022-08-12"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T196852-","G196853-","T196854-"]}}},{"name":"OR086979","node_attrs":{"div":2,"accession":"OR086979","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_170/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR086979/2022-07-27"},"date":{"value":"2022-07-27"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C33863T","-151508A","-151509A","-151510T","-151511G","-151512T","-151513C","-151514T","-151515C","-151516G","-151517T","-151518G","-151519G","-151520G","-151521G","-151522C","-151523A","-151524T","T196618-","A196619-"],"OPG052":["E45K"]},"labels":{"aa":"OPG052: E45K"}}},{"name":"OR086964","node_attrs":{"div":1,"accession":"OR086964","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_155/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR086964/2022-07-27"},"date":{"value":"2022-07-27"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000082","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G64522A","T133102-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"]}},"children":[{"name":"OR095045","node_attrs":{"div":1,"accession":"OR095045","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_227/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR095045/2022-08-12"},"date":{"value":"2022-08-12"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-606T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196614A"]}}},{"name":"OX297403","node_attrs":{"div":1,"accession":"OX297403","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX297403/2022-08-09"},"date":{"value":"2022-08-09"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{"nuc":["T133101-"]}}},{"name":"OX261749","node_attrs":{"div":1,"accession":"OX261749","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX261749/2022-07-20"},"date":{"value":"2022-07-20"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{"nuc":["-133102T","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-"]}}}]},{"name":"NODE_0000083","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C13653T","C116100T","G150376A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG025":["D539N"],"OPG176":["D190N"]},"labels":{"aa":"OPG025: D539N; OPG176: D190N"}},"children":[{"name":"LC722946","node_attrs":{"div":3,"accession":"LC722946","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/TKY220091/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC722946/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000084","node_attrs":{"div":5,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G121971A","G187059A"]}},"children":[{"name":"OP588282","node_attrs":{"div":6,"accession":"OP588282","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI419"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP588282/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G44231A","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OP689687","node_attrs":{"div":5,"accession":"OP689687","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI534"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP689687/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"OQ773494","node_attrs":{"div":7,"accession":"OQ773494","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI875"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ773494/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G86751A","G86752A","G150551-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG108":["A103V"]},"labels":{"aa":"OPG108: A103V"}}}]}]},{"name":"NODE_0000085","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G169928A"],"OPG197":["D87N"]},"labels":{"aa":"OPG197: D87N"}},"children":[{"name":"NODE_0000086","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G10118A","C15004T"],"OPG021":["E178K"]},"labels":{"aa":"OPG021: E178K"}},"children":[{"name":"ON983165","node_attrs":{"div":5,"accession":"ON983165","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3686/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON983165/2022-06-14"},"date":{"value":"2022-06-14"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["G16819A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A163211-","A163212-","C163213-","T163214-","C180825T"],"OPG029":["S84L"],"OPG209":["S103F"]},"labels":{"aa":"OPG029: S84L; OPG209: S103F"}}},{"name":"ON751962","node_attrs":{"div":3,"accession":"ON751962","author":{"author":"Claro,I.M.,de Lima,E.L.,Romano,C.M.,Candido,D.S.,Lindoso,J.A.L.,Barra,L.A.C.,Borges,L.M.S.,Medeiros,L.A.,Tomishige,M.Y.S.,Ramundo,M.S.,Moutinho,T.,da Silva,A.J.D.,Rodrigues,C.C.M.,de Azevedo,L.C.F.,Villas-Boas,L.S.,da Silva,C.A.M.,Coletti,T.M.,O'Toole,A.,Quick,J.,Loman,N.,Rambaut,A.,Faria,N.R.,Figueiredo-Mello,C.,Sabino,E.C.","value":"Claro,I.M.,de Lima,E.L.,Romano,C.M.,Candido,D.S.,Lindoso,J.A.L.,Barra,L.A.C.,Borges,L.M.S.,Medeiros,L.A.,Tomishige,M.Y.S.,Ramundo,M.S.,Moutinho,T.,da Silva,A.J.D.,Rodrigues,C.C.M.,de Azevedo,L.C.F.,Villas-Boas,L.S.,da Silva,C.A.M.,Coletti,T.M.,O'Toole,A.,Quick,J.,Loman,N.,Rambaut,A.,Faria,N.R.,Figueiredo-Mello,C.,Sabino,E.C."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/BR0001/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Imperial College London, School of Public Health"},"strain_display":{"value":"Brazil/ON751962/2022-06-07"},"date":{"value":"2022-06-07"},"country":{"value":"Brazil"}},"branch_attrs":{"mutations":{"nuc":["T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","G173575-","A173576-","G173577-","A173578-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000087","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G58518A"]}},"children":[{"name":"OP626120","node_attrs":{"div":8,"accession":"OP626120","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI482"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP626120/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G3079A","C23345T","C23353T","C23356T","C151626T","C157938T","C194131T"],"OPG003":["S510L"],"OPG003_dup":["S510L"],"OPG039":["D255N","D256N"],"OPG178":["Q40*"]},"labels":{"aa":"OPG003: S510L; OPG003_dup: S510L; OPG039: D255N, D256N; OPG178: Q40*"}}},{"name":"OP594200","node_attrs":{"div":4,"accession":"OP594200","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI436"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP594200/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G59922A","G112249A"],"OPG131":["E104K"]},"labels":{"aa":"OPG131: E104K"}}}]}]},{"name":"NODE_0000088","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G70190A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG089":["E109K"]},"labels":{"aa":"OPG089: E109K"}},"children":[{"name":"ON954773","node_attrs":{"div":2,"accession":"ON954773","author":{"author":"Gigante,C.M.,Ventura,J.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y.","value":"Gigante,C.M.,Ventura,J.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_CA002"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"strain_display":{"value":"USA/ON954773/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G83568A"],"OPG105":["A815T"]},"labels":{"aa":"OPG105: A815T"}}},{"name":"OQ427119","node_attrs":{"div":2,"accession":"OQ427119","author":{"author":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Weigand,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y.","value":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Weigand,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_OH0004"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ427119/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G126310A","A173316-","T173317-"],"OPG148":["E109K"]},"labels":{"aa":"OPG148: E109K"}}},{"name":"OR035734","node_attrs":{"div":2,"accession":"OR035734","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_128"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035734/2022-10-10"},"date":{"value":"2022-10-10"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G164038A","T196712-","A196713-","T196714-"],"OPG189":["E236K"]},"labels":{"aa":"OPG189: E236K"}}},{"name":"OR035673","node_attrs":{"div":3,"accession":"OR035673","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_67"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035673/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G60855A","G71907A"]}}}]},{"name":"NODE_0000089","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C77462T"],"OPG098":["S188F"]},"labels":{"aa":"OPG098: S188F"}},"children":[{"name":"OP440592","node_attrs":{"div":1,"accession":"OP440592","author":{"author":"Hemarajata,P.,Green,N.M.","value":"Hemarajata,P.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00013/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP440592/2022-07-22"},"date":{"value":"2022-07-22"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A763-","A764-","T765-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196715-","T196716-","T196717-"]}}},{"name":"OP451007","node_attrs":{"div":1,"accession":"OP451007","author":{"author":"Gigante,C.M.,Pavlick,J.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y.","value":"Gigante,C.M.,Pavlick,J.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_GA0009"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP451007/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000090","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C111164T","A143676G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C152385T"],"OPG130":["E247K"],"OPG165":["N54S"]},"labels":{"aa":"OPG130: E247K; OPG165: N54S"}},"children":[{"name":"OR759186","node_attrs":{"div":4,"accession":"OR759186","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL098/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759186/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"OR759183","node_attrs":{"div":4,"accession":"OR759183","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL095/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759183/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000091","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G106113A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C189810T"]}},"children":[{"name":"OQ644781","node_attrs":{"div":8,"accession":"OQ644781","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00475/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ644781/2022-11-22"},"date":{"value":"2022-11-22"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G13224A","C22664T","C23353T","G24446A","G25294A","C25308T"],"OPG024":["S2L"],"OPG038":["D166N"],"OPG039":["D256N"],"OPG040":["S62L","P345S"]},"labels":{"aa":"OPG024: S2L; OPG038: D166N; OPG039: D256N; OPG040: S62L, P345S"}}},{"name":"NODE_0000092","node_attrs":{"div":5,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G66587A","G143857A","C144237T","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG165":["S241L"]},"labels":{"aa":"OPG165: S241L"}},"children":[{"name":"OQ918699","node_attrs":{"div":5,"accession":"OQ918699","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00488/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ918699/2023-02-20"},"date":{"value":"2023-02-20"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","-179176A","-179177T","-179178A"]}}},{"name":"OQ918700","node_attrs":{"div":5,"accession":"OQ918700","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00489/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ918700/2023-02-20"},"date":{"value":"2023-02-20"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OQ918698","node_attrs":{"div":5,"accession":"OQ918698","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00487/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ918698/2023-02-20"},"date":{"value":"2023-02-20"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179082C","-179083A","-179084T","-179085T","-179086A","-179087T","-179088A","-179089T","-179090A","-179091C","-179092A","-179093T","-179094T","-179095A","-179096T","-179097A","-179098T","-179099A","-179100C","-179101A","-179102T","-179103T","-179104A","-179105T","-179106A","-179107T","-179108A","-179109C","-179110A","-179111T","-179112T","-179113A","-179114T","-179115A","-179116T","-179117A","-179118C","-179119A","-179120T","-179121T","-179122A","-179123T","-179124A","-179125T","-179126A","-179127C","-179128A","-179129T","-179130T","-179131A","-179132T","-179133A","-179134T","-179135A","-179136C","-179137A","-179138T","-179139T","-179140A","-179141T","-179142A","-179143T","-179144A","-179145C","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-"]}}}]}]},{"name":"NODE_0000093","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C34784T","C101418T","G109844A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG054":["D405N"],"OPG120":["D111N"]},"labels":{"aa":"OPG054: D405N; OPG120: D111N"}},"children":[{"name":"OR743495","node_attrs":{"div":4,"accession":"OR743495","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1026"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR743495/2023-09-XX"},"date":{"value":"2023-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G145312A","-179194A","-179195T","C179265-","A179266-","T179267-"]}}},{"name":"OR743494","node_attrs":{"div":3,"accession":"OR743494","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1025"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR743494/2023-09-XX"},"date":{"value":"2023-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000094","node_attrs":{"div":6,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C45528T","C84767T","C170791T"],"OPG064":["R124K"]},"labels":{"aa":"OPG064: R124K"}},"children":[{"name":"OR743498","node_attrs":{"div":6,"accession":"OR743498","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1029"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR743498/2023-10-XX"},"date":{"value":"2023-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-179263G","-179264C"]}}},{"name":"OR743497","node_attrs":{"div":8,"accession":"OR743497","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1028"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR743497/2023-10-XX"},"date":{"value":"2023-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G143777A","G175934A","-179194A","-179195T","C179265-","A179266-","T179267-"],"OPG165":["V88I"]},"labels":{"aa":"OPG165: V88I"}}}]}]},{"name":"OR126131_NODE_0000067_merged","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C141757T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OR126131","node_attrs":{"div":5,"accession":"OR126131","author":{"author":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C.","value":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"HRYC_MPXV001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Hospital Ramon y Cajal, Microbiology"},"strain_display":{"value":"Spain/OR126131/2022-09-21"},"date":{"value":"2022-09-21"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["C11749-","C34432T","C48324T","G101294A","G190695A"],"OPG016":["E96K"],"OPG053":["E87K"],"OPG120":["S152L"]},"labels":{"aa":"OPG016: E96K; OPG053: E87K; OPG120: S152L"}}},{"name":"NODE_0000067","node_attrs":{"div":3,"lineage":{"value":"B.1.18"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C43706T","T124690C"]},"labels":{"clade":"B.1.18"}},"children":[{"name":"OP628451","node_attrs":{"div":3,"accession":"OP628451","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.18"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-083401/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP628451/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OQ148474","node_attrs":{"div":9,"accession":"OQ148474","author":{"author":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"lineage":{"value":"B.1.18"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LBMB-UTP_MP-025_VAC"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"strain_display":{"value":"Colombia/OQ148474/2022-11-15"},"date":{"value":"2022-11-15"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G67758A","C128242T","G144572A","C166940T","C168829T","C170049T"],"OPG150":["S155F"],"OPG166":["A59T"]},"labels":{"aa":"OPG150: S155F; OPG166: A59T"}}},{"name":"OQ557948","node_attrs":{"div":8,"accession":"OQ557948","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"lineage":{"value":"B.1.18"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_NY0009"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ557948/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G24063A","C25370T","G54088A","G108462A","C159779T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG039":["S19F"],"OPG040":["E37K"],"OPG185":["S288L"]},"labels":{"aa":"OPG039: S19F; OPG040: E37K; OPG185: S288L"}}}]}]},{"name":"NODE_0000095","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C6310T","C81194T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G190900A"],"OPG016":["R164K"]},"labels":{"aa":"OPG016: R164K"}},"children":[{"name":"OQ503839","node_attrs":{"div":4,"accession":"OQ503839","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00463/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ503839/2023-01-26"},"date":{"value":"2023-01-26"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A39081T","C102294T","T179244-"],"OPG057":["I372N"],"OPG121":["Q169*"]},"labels":{"aa":"OPG057: I372N; OPG121: Q169*"}}},{"name":"NODE_0000096","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","A39482C","A170123-","T170124-","A170125-","A170126-","C179145-"],"OPG057":["H238Q"],"OPG198":["K30-"]},"labels":{"aa":"OPG057: H238Q; OPG198: K30-"}},"children":[{"name":"OP680504","node_attrs":{"div":3,"accession":"OP680504","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00226/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP680504/2022-10-03"},"date":{"value":"2022-10-03"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OQ503844","node_attrs":{"div":3,"accession":"OQ503844","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00468/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ503844/2023-01-26"},"date":{"value":"2023-01-26"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-","A181373-","T181374-","C181375-","T181376-","C181377-","T181378-","G181379-","G181380-","C181381-","T181382-","A181383-","T181384-","A181385-","T181386-","A181387-","T181388-","C181389-","T181390-","T181391-","A181392-","C181393-","G181394-","G181395-","T181396-","G181397-","A181398-","C181399-","A181400-","T181401-","G181402-","T181403-","T181404-","C181405-","G181406-","T181407-","G181408-","G181409-","T181410-","G181411-","T181412-","T181413-","A181414-","T181415-","G181416-","A181417-","A181418-","A181419-","C181420-","A181421-","T181422-","G181423-","T181424-","A181425-","T181426-","G181427-","A181428-","G181429-","A181430-","A181431-","A181432-","A181433-","A181434-","C181435-","T181436-","G181437-","C181438-","G181439-","T181440-","T181441-","G181442-","T181443-","A181444-","T181445-","C181446-","A181447-","T181448-","G181449-","A181450-","C181451-"]}}}]},{"name":"NODE_0000097","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G159399A","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"]}},"children":[{"name":"OP689657","node_attrs":{"div":3,"accession":"OP689657","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI504"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP689657/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OP689655","node_attrs":{"div":3,"accession":"OP689655","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI502"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP689655/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000098","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C118453T","G137276A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177009A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG136":["E379K"],"OPG153":["S131F"],"OPG205":["E452K"]},"labels":{"aa":"OPG136: E379K; OPG153: S131F; OPG205: E452K"}},"children":[{"name":"OQ331006","node_attrs":{"div":4,"accession":"OQ331006","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00397/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ331006/2023-01-03"},"date":{"value":"2023-01-03"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G635-","A636-","A637-","G39327A","T196627-","C196628-","T196629-"],"OPG057":["A290V"]},"labels":{"aa":"OPG057: A290V"}}},{"name":"NODE_0000099","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C117119T"]}},"children":[{"name":"OQ331007","node_attrs":{"div":4,"accession":"OQ331007","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00398/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ331007/2023-01-03"},"date":{"value":"2023-01-03"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499970","node_attrs":{"div":4,"accession":"OR499970","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00513/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499970/2023-05-04"},"date":{"value":"2023-05-04"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T605-"]}}},{"name":"OR499971","node_attrs":{"div":6,"accession":"OR499971","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00514/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499971/2023-05-04"},"date":{"value":"2023-05-04"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T39397C","T178873C","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG057":["N267D"]},"labels":{"aa":"OPG057: N267D"}}},{"name":"OR499968","node_attrs":{"div":5,"accession":"OR499968","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00511/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499968/2023-05-04"},"date":{"value":"2023-05-04"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T39076-","T39077-","T39078-","A39079-","A39080-","A39081-","T39082-","T39083-","T39084-","A176368T","A190409-","A190410-","T190411-","G190412-","G190413-","A190414-","T190415-","T190416-","C190417-","G190418-","C190419-","G190420-","T190421-","A190422-","T190423-","A190424-","G190425-","C190426-","T190427-","A190428-","T190429-","T190430-","T190431-","A190432-","C190433-","G190434-","T190435-","A190436-","T190437-","T190438-","A190439-","G190440-","T190441-","A190442-","T190443-","C190444-","G190445-","G190446-","C190447-","A190448-","T190449-","C190450-","T190451-","C190452-","T190453-","T190454-","T190455-","T190456-","G190457-","T190458-","A190459-","T190460-","C190461-","T190462-","T190463-","G190464-","T190465-","T190466-","A190467-","A190468-","T190469-","T190470-","G190471-","T190472-","C190473-","A190474-","C190475-","A190476-","A190477-","A190478-","C190479-","T190480-","A190481-","G190482-","T190483-","A190484-","C190485-","A190486-","T190487-","T190488-","A190489-","C190490-","T190491-","T190492-","C190493-","A190494-","A190495-","T190496-","C190497-","T190498-","G190499-","A190500-","A190501-","A190502-","A190503-","T190504-","A190505-"],"OPG205":["E238V"]},"labels":{"aa":"OPG205: E238V"}}}]}]},{"name":"NODE_0000100","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G50982A","T133102-","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OR035670","node_attrs":{"div":3,"accession":"OR035670","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_64"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035670/2022-06-24"},"date":{"value":"2022-06-24"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C71644T","C127445T","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"],"OPG091":["S92L"],"OPG149":["P84S"]},"labels":{"aa":"OPG091: S92L; OPG149: P84S"}}},{"name":"OR035643","node_attrs":{"div":1,"accession":"OR035643","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_37"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035643/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-133102T"]}}},{"name":"OR030943","node_attrs":{"div":1,"accession":"OR030943","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_32"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR030943/2022-07-15"},"date":{"value":"2022-07-15"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133101-"]}}},{"name":"NODE_0000101","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G28334A","G47240A","C48569T"],"OPG044":["E82K"]},"labels":{"aa":"OPG044: E82K"}},"children":[{"name":"OR095057","node_attrs":{"div":4,"accession":"OR095057","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_239/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR095057/2022-08-12"},"date":{"value":"2022-08-12"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T196852-","G196853-","T196854-"]}}},{"name":"OR095054","node_attrs":{"div":4,"accession":"OR095054","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_236/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR095054/2022-08-12"},"date":{"value":"2022-08-12"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000102","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C156429T"]}},"children":[{"name":"NODE_0000103","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G162265A","C165278T"],"OPG188":["E224K"],"OPG190":["H53Y"]},"labels":{"aa":"OPG188: E224K; OPG190: H53Y"}},"children":[{"name":"OP019277","node_attrs":{"div":3,"accession":"OP019277","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1531254/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP019277/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP555487","node_attrs":{"div":4,"accession":"OP555487","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0391/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555487/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C139646T"],"OPG158":["E42K"]},"labels":{"aa":"OPG158: E42K"}}}]},{"name":"NODE_0000104","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C65571T","G144988A"]}},"children":[{"name":"OP013006","node_attrs":{"div":3,"accession":"OP013006","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3542/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP013006/2022-06-07"},"date":{"value":"2022-06-07"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"OP013017","node_attrs":{"div":3,"accession":"OP013017","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3752/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP013017/2022-06-10"},"date":{"value":"2022-06-10"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"OP270027","node_attrs":{"div":4,"accession":"OP270027","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-4024/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP270027/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C181455T"],"OPG210":["Q34*"]},"labels":{"aa":"OPG210: Q34*"}}},{"name":"OP270025","node_attrs":{"div":6,"accession":"OP270025","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-4014/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP270025/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T","C45103T","G74933A","G131867A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG064":["E266K"],"OPG095":["R44Q"],"OPG151":["E982K"]},"labels":{"aa":"OPG064: E266K; OPG095: R44Q; OPG151: E982K"}}}]}]},{"name":"NODE_0000105","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C21128T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-196615A"],"OPG037":["E436K"]},"labels":{"aa":"OPG037: E436K"}},"children":[{"name":"OR264408","node_attrs":{"div":1,"accession":"OR264408","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"39_K"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264408/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}},{"name":"ON631963","node_attrs":{"div":1,"accession":"ON631963","author":{"author":"Hammerschlag,Y.,MacLeod,G.,Papadakis,G.,Adnan Sanchez,A.,Druce,J.,Savic,I.,Taiaroa,G.,Roberts,J.,Caly,L.,Williamson,D.A.,Cheng,A.C.,McMahon,J.H.","value":"Hammerschlag,Y.,MacLeod,G.,Papadakis,G.,Adnan Sanchez,A.,Druce,J.,Savic,I.,Taiaroa,G.,Roberts,J.,Caly,L.,Williamson,D.A.,Cheng,A.C.,McMahon,J.H."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPxV/VIDRL01/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"Victorian Infectious Diseases Reference Laboratory, Doherty Institute, Australia"},"strain_display":{"value":"Australia/ON631963/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["C133077T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264407","node_attrs":{"div":1,"accession":"OR264407","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"39_I"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264407/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000107","node_attrs":{"div":5,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T607-","A22452T","C66718T","C144356T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","C188683T","A196615-"],"OPG084":["S666L"]},"labels":{"aa":"OPG084: S666L"}},"children":[{"name":"OR264405","node_attrs":{"div":5,"accession":"OR264405","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"39_G"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264405/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}},{"name":"OR264404","node_attrs":{"div":5,"accession":"OR264404","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"39_D"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264404/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264406","node_attrs":{"div":5,"accession":"OR264406","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"39_H"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264406/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"]}}}]}]},{"name":"NODE_0000108","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C53342T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG071":["R366K"]},"labels":{"aa":"OPG071: R366K"}},"children":[{"name":"OQ451902","node_attrs":{"div":6,"accession":"OQ451902","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI717"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ451902/2022-11-XX"},"date":{"value":"2022-11-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-607T","C3602T","C124495T","G159789A","C170573T","G190695A","G193608A"],"OPG003":["E336K"],"OPG003_dup":["E336K"],"OPG016":["E96K"],"OPG198":["S179L"]},"labels":{"aa":"OPG003: E336K; OPG003_dup: E336K; OPG016: E96K; OPG198: S179L"}}},{"name":"NODE_0000109","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C156205T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}},"children":[{"name":"OP748969","node_attrs":{"div":2,"accession":"OP748969","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00283/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP748969/2022-10-19"},"date":{"value":"2022-10-19"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OP748964","node_attrs":{"div":2,"accession":"OP748964","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00278/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP748964/2022-10-20"},"date":{"value":"2022-10-20"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OQ427135","node_attrs":{"div":3,"accession":"OQ427135","author":{"author":"Gigante,C.,Steidley,B.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Davizon,E.,Li,Y.","value":"Gigante,C.,Steidley,B.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Davizon,E.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_CO0004"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ427135/2022-11-XX"},"date":{"value":"2022-11-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G120238A","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","T136555-","A136556-","T136557-","G136558-","A136559-","T136560-","A136561-","T136562-","C136563-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG137":["E213K"],"OPG153":["I370-","I371-","D372-","D373-","D374-","D375-","D376-"]},"labels":{"aa":"OPG137: E213K; OPG153: I370-, I371-, D372-, D373-, D374-, D375-, D376-"}}},{"name":"NODE_0000110","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C109535T","A136516-","T136517-","A196657-","T196658-","A196659-"]}},"children":[{"name":"OQ331002","node_attrs":{"div":3,"accession":"OQ331002","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00374/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ331002/2022-11-23"},"date":{"value":"2022-11-23"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OQ331001","node_attrs":{"div":6,"accession":"OQ331001","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00373/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ331001/2022-11-23"},"date":{"value":"2022-11-23"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A763-","A764-","T765-","A11160G","T20384A","T130733C","-179145C","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","C196738-","C196739-","T196740-"],"OPG023":["F581L"],"OPG151":["C604R"]},"labels":{"aa":"OPG023: F581L; OPG151: C604R"}}}]}]}]},{"name":"NODE_0000111","node_attrs":{"div":1,"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G181367A","A196614-"]},"labels":{"clade":"B.1.9"}},"children":[{"name":"ON843175","node_attrs":{"div":1,"accession":"ON843175","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0043/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/ON843175/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000112","node_attrs":{"div":2,"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G176823A"],"OPG205":["E390K"]},"labels":{"aa":"OPG205: E390K"}},"children":[{"name":"ON880538","node_attrs":{"div":3,"accession":"ON880538","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3336/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880538/2022-06-01"},"date":{"value":"2022-06-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C32627T"]}}},{"name":"NODE_0000113","node_attrs":{"div":3,"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-606T","A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","C57110T","-196614A"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG074":["E6K"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG074: E6K"}},"children":[{"name":"ON649713","node_attrs":{"div":3,"accession":"ON649713","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0020/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"strain_display":{"value":"Portugal/ON649713/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OP555532","node_attrs":{"div":4,"accession":"OP555532","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0451/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555532/2022-08-04"},"date":{"value":"2022-08-04"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159148A"],"OPG185":["D78N"]},"labels":{"aa":"OPG185: D78N"}}}]},{"name":"NODE_0000114","node_attrs":{"div":4,"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C34432T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155157A"],"OPG053":["E87K"],"OPG181":["R249K"]},"labels":{"aa":"OPG053: E87K; OPG181: R249K"}},"children":[{"name":"OP555506","node_attrs":{"div":4,"accession":"OP555506","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0413/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555506/2022-07-26"},"date":{"value":"2022-07-26"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000115","node_attrs":{"div":5,"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C68792T"]}},"children":[{"name":"OP555608","node_attrs":{"div":5,"accession":"OP555608","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0537/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555608/2022-08-19"},"date":{"value":"2022-08-19"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OP555607","node_attrs":{"div":6,"accession":"OP555607","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0536/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555607/2022-08-22"},"date":{"value":"2022-08-22"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G13563A"],"OPG025":["P569S"]},"labels":{"aa":"OPG025: P569S"}}}]}]}]}]},{"name":"NODE_0000116","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G102694A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}},"children":[{"name":"OP863230","node_attrs":{"div":6,"accession":"OP863230","author":{"author":"Haw,M.,Probert,W.,Espinosa,A.,Kath,C.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Haw,M.,Probert,W.,Espinosa,A.,Kath,C.,O'Neil,R.,Bell,J.,Hacker,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/CA-CDPH-000056/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDPH, VRDL"},"strain_display":{"value":"USA/OP863230/2022-10-07"},"date":{"value":"2022-10-07"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A31053G","G34502A","G147352A","G151540A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G189258A"],"OPG047":["C48R"],"OPG171":["R122K"],"OPG178":["G11E"]},"labels":{"aa":"OPG047: C48R; OPG171: R122K; OPG178: G11E"}}},{"name":"NODE_0000117","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G28490A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG044":["D134N"]},"labels":{"aa":"OPG044: D134N"}},"children":[{"name":"OP422342","node_attrs":{"div":3,"accession":"OP422342","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1539124/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP422342/2022-08-02"},"date":{"value":"2022-08-02"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{"nuc":["C110960T"]}}},{"name":"OP422341","node_attrs":{"div":2,"accession":"OP422341","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1538395/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP422341/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000118","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C179853T"]}},"children":[{"name":"OP555651","node_attrs":{"div":3,"accession":"OP555651","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0580/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555651/2022-09-09"},"date":{"value":"2022-09-09"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C121514T"],"OPG140":["G78E"]},"labels":{"aa":"OPG140: G78E"}}},{"name":"OP555639","node_attrs":{"div":3,"accession":"OP555639","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0568/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555639/2022-09-02"},"date":{"value":"2022-09-02"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G101192A"],"OPG120":["P186L"]},"labels":{"aa":"OPG120: P186L"}}}]},{"name":"NODE_0000119","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C12684T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG023":["E73K"]},"labels":{"aa":"OPG023: E73K"}},"children":[{"name":"OQ331004","node_attrs":{"div":2,"accession":"OQ331004","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00393/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ331004/2022-12-13"},"date":{"value":"2022-12-13"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OQ644787","node_attrs":{"div":3,"accession":"OQ644787","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00481/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ644787/2023-01-18"},"date":{"value":"2023-01-18"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G90825A"]}}}]}]},{"name":"NODE_0000120","node_attrs":{"div":2,"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G36617A","C159779T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG055":["S156L"],"OPG185":["S288L"]},"labels":{"aa":"OPG055: S156L; OPG185: S288L","clade":"B.1.14"}},"children":[{"name":"ON959133","node_attrs":{"div":2,"accession":"ON959133","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_NY002"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"strain_display":{"value":"USA/ON959133/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"ON959135","node_attrs":{"div":4,"accession":"ON959135","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_NY004"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"strain_display":{"value":"USA/ON959135/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G2132A","G96835A","C195078T"],"OPG002":["S207L"],"OPG002_dup":["S207L"],"OPG117":["D263N"]},"labels":{"aa":"OPG002: S207L; OPG002_dup: S207L; OPG117: D263N"}}},{"name":"ON694342","node_attrs":{"div":2,"accession":"ON694342","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI011"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON694342/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-606T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-","-196614A"]}}},{"name":"OR086956","node_attrs":{"div":5,"accession":"OR086956","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_147/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR086956/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-606T","C22880T","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","G158617A","C170573T"],"OPG038":["E94K"],"OPG198":["S179L"]},"labels":{"aa":"OPG038: E94K; OPG198: S179L"}}},{"name":"OX009124","node_attrs":{"div":4,"accession":"OX009124","author":{"author":"Pettke,A.,Filen,F.,Asgeirsson,H.,Glans,H.,Widgren,K.,Muradrasoli,S.,Helgesson,S.,Karlberg,M.L.,Walai,N.,Bjerkner,A.,Gourle,H.,Lindsjo,O.K.,Sonden,K.","value":"Pettke,A.,Filen,F.,Asgeirsson,H.,Glans,H.,Widgren,K.,Muradrasoli,S.,Helgesson,S.,Karlberg,M.L.,Walai,N.,Bjerkner,A.,Gourle,H.,Lindsjo,O.K.,Sonden,K."},"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Lesion"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Public Health Agency of Sweden, Unit for Laboratory Development and Technology Transfer , Folkhalsomyndigheten, 171 82 Solna"},"strain_display":{"value":"Sweden/OX009124/2022-05-22"},"date":{"value":"2022-05-22"},"country":{"value":"Sweden"}},"branch_attrs":{"mutations":{"nuc":["T602-","T603-","T604-","T605-","A8055-","A28529-","A28530-","T47054-","T76087-","T88836-","A91705-","A92907-","T103367-","T104687-","T148344A","A148345T","A151680-","A162904-","T163342-","T163597-","A170728-"],"OPG044":["K147-"],"OPG113":["I393-"],"OPG178":["T58-"],"OPG188":["K437-"],"OPG189":["F4-"],"OPG198":["K231-"]},"labels":{"aa":"OPG044: K147-; OPG113: I393-; OPG178: T58-; OPG188: K437-; OPG189: F4-; OPG198: K231-"}}},{"name":"NODE_0000121","node_attrs":{"div":3,"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G171270A","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","-196614A"],"OPG199":["D95N"]},"labels":{"aa":"OPG199: D95N"}},"children":[{"name":"OP382493","node_attrs":{"div":6,"accession":"OP382493","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00016"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382493/2022-07-22"},"date":{"value":"2022-07-22"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["G25999A","G97417A","G100939A"],"OPG042":["Q367*"],"OPG117":["E457K"]},"labels":{"aa":"OPG042: Q367*; OPG117: E457K"}}},{"name":"OP382492","node_attrs":{"div":4,"accession":"OP382492","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00015"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382492/2022-07-22"},"date":{"value":"2022-07-22"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["G161913A","A196856-","A196857-","A196858-"]}}},{"name":"OP555644","node_attrs":{"div":5,"accession":"OP555644","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0573/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555644/2022-09-06"},"date":{"value":"2022-09-06"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T594A","-606T","-607T","-608T","-609T","C93713T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G158549A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A","-196616T"]}}}]}]},{"name":"NODE_0000122","node_attrs":{"div":4,"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C9389T","C30154T","G161797A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A179266-","T179267-","A179270-","T179271-","A179272-","T179273-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","A179282-","A185557C"],"OPG188":["E68K"],"OPG210":["K1401T"]},"labels":{"aa":"OPG188: E68K; OPG210: K1401T","clade":"B.1.16"}},"children":[{"name":"OP459211","node_attrs":{"div":5,"accession":"OP459211","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-23596-O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"strain_display":{"value":"Colombia/OP459211/2022-08-29"},"date":{"value":"2022-08-29"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G170076A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP819959","node_attrs":{"div":6,"accession":"OP819959","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"SAN_INS_MPX_0971_L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP819959/2022-10-11"},"date":{"value":"2022-10-11"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G23673A","G37974A","-179266A","-179267T","-179270A","-179271T","-179272A","-179273T","-179275T","-179276T","-179277T","-179278A","-179279A","-179280A","-179282A"],"OPG039":["S149L"],"OPG056":["S354L"]},"labels":{"aa":"OPG039: S149L; OPG056: S354L"}}},{"name":"OP693647","node_attrs":{"div":4,"accession":"OP693647","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"DC_INS_MPX_0082_L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP693647/2022-08-08"},"date":{"value":"2022-08-08"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A1701-","C1702-","T1703-","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-","T196852-","G196853-","T196854-"]}}},{"name":"OQ197861","node_attrs":{"div":7,"accession":"OQ197861","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Rosales,A.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Rosales,A.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"DC_INS_MPX-1118-H"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OQ197861/2022-10-20"},"date":{"value":"2022-10-20"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G23118A","G74167A","T110647C","C179265-","G179268-","G179269-","C179274-","G179281-"],"OPG094":["D130N"],"OPG129":["T120A"]},"labels":{"aa":"OPG094: D130N; OPG129: T120A"}}},{"name":"NODE_0000123","node_attrs":{"div":5,"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G148403A"]}},"children":[{"name":"OP819955","node_attrs":{"div":13,"accession":"OP819955","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"VAC_INS_MPX_0962_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP819955/2022-10-13"},"date":{"value":"2022-10-13"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C53865T","C57810T","G69840A","C117200T","C124379T","G161421A","C178546T","-179266A","-179267T","-179270A","-179271T","-179272A","-179273T","-179275T","-179276T","-179277T","-179278A","-179279A","-179280A","-179282A","C188775T"],"OPG071":["D192N"],"OPG145":["H145Y"],"OPG187":["R267K"]},"labels":{"aa":"OPG071: D192N; OPG145: H145Y; OPG187: R267K"}}},{"name":"OP819954","node_attrs":{"div":7,"accession":"OP819954","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"VAC_INS_MPX_0960_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP819954/2022-10-15"},"date":{"value":"2022-10-15"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G89896A","G164843A","-179266A","-179267T","-179270A","-179271T","-179272A","-179273T","-179275T","-179276T","-179277T","-179278A","-179279A","-179280A","-179282A"],"OPG110":["E89K"],"OPG189":["G504E"]},"labels":{"aa":"OPG110: E89K; OPG189: G504E"}}},{"name":"OQ148473","node_attrs":{"div":6,"accession":"OQ148473","author":{"author":"Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LBMB-UTP_MP-021_VAC"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"strain_display":{"value":"Colombia/OQ148473/2022-11-11"},"date":{"value":"2022-11-11"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C133212-","C133213-","T133214-","C133215-","G133216-","A133217-","G133218-","T133219-","C133220-","T133221-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","C179265-","G179268-","G179269-","C179274-","G179281-","C188896T"]}}},{"name":"OQ696095","node_attrs":{"div":7,"accession":"OQ696095","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-30094O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ696095/2022-11-08"},"date":{"value":"2022-11-08"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","G104597A","C116175T","G150568A","C179265-","G179268-","G179269-","C179274-","G179281-"]}}}]}]},{"name":"NODE_0000124","node_attrs":{"div":2,"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","G149818A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G151362A"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG176":["D4N"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG176: D4N","clade":"B.1.15"}},"children":[{"name":"ON694335","node_attrs":{"div":2,"accession":"ON694335","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI018"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON694335/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-","A196614-"]}}},{"name":"OP484673","node_attrs":{"div":5,"accession":"OP484673","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI352"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP484673/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C21128T","G74187T","C151111T"],"OPG037":["E436K"],"OPG094":["Q136H"]},"labels":{"aa":"OPG037: E436K; OPG094: Q136H"}}},{"name":"NODE_0000125","node_attrs":{"div":7,"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C8385T","-11326A","-11327T","-11328C","-11329T","-11330A","-11331C","-11332G","-11333A","-11334T","-11335A","-11336T","-11337T","-11338A","-11339G","-11340A","-11341T","-11342A","-11343C","-11344T","-11345T","-11346C","-11347A","-11348C","-11349T","-11350C","-11351A","-11352A","-11353T","-11354G","-11355A","-11356A","-11357T","-11358C","-11359A","-11360A","-11361T","-11362C","-11363A","-11364C","-11365A","-11366C","-11367A","-11368A","-11369T","-11370C","-11371T","-11372A","-11373A","-11374T","-11375G","-11376T","-11377A","-11378G","-11379G","-11380T","-11381T","-11382T","-11383A","-11384T","-11385G","-11386A","-11387C","-11388A","-11389T","-11390A","-11391A","-11392T","-11393A","-11394G","-11395C","-11396A","-11397T","-11398T","-11399T","-11400T","-11401C","-11402A","-11403G","-11404C","-11405A","-11406G","-11407T","-11408T","-11409C","-11410A","-11411A","-11412T","-11413G","-11414T","-11415T","-11416T","-11417C","-11418T","-11419A","-11420G","-11421A","-11422T","-11423T","-11424C","-11425G","-11426T","-11427T","-11428G","-11429A","-11430T","-11431G","-11432G","-11433C","-11434A","-11435A","-11436T","-11437G","-11438G","-11439T","-11440T","-11441A","-11442T","-11443A","-11444C","-11445A","-11446T","-11447G","-11448T","-11449A","-11450T","-11451A","-11452T","-11453C","-11454C","-11455G","-11456T","-11457T","-11458A","-11459T","-11460T","-11461T","-11462G","-11463A","-11464T","-11465C","-11466T","-11467A","-11468A","-11469T","-11470G","-11471T","-11472T","-11473G","-11474A","-11475C","-11476A","-11477T","-11478C","-11479T","-11480G","-11481A","-11482A","-11483C","-11484C","-11485G","-11486G","-11487A","-11488T","-11489T","-11490C","-11491T","-11492A","-11493G","-11494C","-11495A","-11496G","-11497T","-11498A","-11499A","-11500A","-11501G","-11502A","-11503T","-11504A","-11505C","-11506T","-11507A","-11508G","-11509A","-11510G","-11511A","-11512T","-11513T","-11514G","-11515T","-11516T","-11517T","-11518A","-11519T","-11520T","-11521A","-11522T","-11523A","-11524T","-11525C","-11526T","-11527A","-11528A","-11529C","-11530A","-11531G","-11532C","-11533C","-11534T","-11535T","-11536G","-11537T","-11538G","-11539A","-11540A","-11541G","-11542A","-11543A","-11544G","-11545T","-11546G","-11547T","-11548T","-11549T","-11550C","-11551T","-11552C","-11553C","-11554T","-11555C","-11556G","-11557T","-11558T","-11559T","-11560G","-11561T","-11562C","-11563A","-11564A","-11565T","-11566C","-11567A","-11568T","-11569G","-11570T","-11571T","-11572A","-11573A","-11574T","-11575G","-11576T","-11577C","-11578T","-11579T","-11580T","-11581A","-11582A","-11583G","-11584A","-11585T","-11586A","-11587A","-11588G","-11589G","-11590T","-11591A","-11592G","-11593A","-11594C","-11595A","-11596A","-11597A","-11598T","-11599G","-11600T","-11601T","-11602T","-11603A","-11604T","-11605A","-11606G","-11607T","-11608A","-11609C","-11610T","-11611A","-11612A","-11613G","-11614A","-11615A","-11616T","-11617T","-11618G","-11619G","-11620G","-11621C","-11622A","-11623A","-11624A","-11625C","-11626A","-11627T","-11628A","-11629A","-11630G","-11631A","-11632C","-11633A","-11634T","-11635G","-11636T","-11637C","-11638A","-11639C","-11640A","-11641A","-11642A","-11643G","-11644A","-11645C","-11646C","-11647C","-11648T","-11649T","-11650T","-11651T","-11652T","-11653G","-11654T","-11655A","-11656T","-11657G","-11658T","-11659A","-11660T","-11661A","-11662A","-11663G","-11664T","-11665G","-11666T","-11667A","-11668G","-11669A","-11670A","-11671A","-11672T","-11673T","-11674A","-11675T","-11676A","-11677A","-11678C","-11679A","-11680T","-11681C","-11682C","-11683A","-11684T","-11685A","-11686G","-11687T","-11688T","-11689G","-11690G","-11691A","-11692T","-11693T","-11694C","-11695A","-11696C","-11697A","-11698T","-11699A","-11700G","-11701G","-11702T","-11703G","-11704T","-11705C","-11706C","-11707A","-11708A","-11709T","-11710C","-11711G","-11712G","-11713G","-11714A","-11715T","-11716C","-11717T","-11718C","-11719T","-11720C","-11721C","-11722A","-11723T","-11724C","-11725A","-11726T","-11727C","-11728G","-11729A","-11730G","-11731A","-11732T","-11733G","-11734A","-11735T","-11736T","-11737G","-11738A","-11739C","-11740G","-11741G","-11742C","-11743A","-11744T","-11745C","-11746T","-11747C","-11748C","-11749C","-11750C","-11751C","-11752T","-11753T","-11754C","-11755C","-11756T","-11757T","-11758T","-11759T","-11760T","-11761T","-11762A","-11763G","-11764T","-11765A","-11766G","-11767A","-11768T","-11769A","-11770T","-11771T","-11772T","-11773C","-11774A","-11775T","-11776C","-11777G","-11778T","-11779G","-11780T","-11781A","-11782A","-11783G","-11784A","-11785A","-11786T","-11787C","-11788A","-11789A","-11790T","-11791A","-11792T","-11793T","-11794A","-11795A","-11796T","-11797A","-11798T","-11799T","-11800T","-11801C","-11802T","-11803A","-11804A","-11805A","-11806G","-11807T","-11808A","-11809T","-11810C","-11811T","-11812G","-11813T","-11814G","-11815T","-11816A","-11817T","-11818A","-11819G","-11820C","-11821C","-11822T","-11823C","-11824T","-11825T","-11826T","-11827A","-11828T","-11829T","-11830T","-11831A","-11832C","-11833C","-11834A","-11835C","-11836A","-11837G","-11838C","-11839T","-11840C","-11841C","-11842A","-11843T","-11844A","-11845T","-11846T","-11847C","-11848C","-11849A","-11850A","-11851C","-11852A","-11853T","-11854G","-11855C","-11856A","-11857T","-11858T","-11859C","-11860C","-11861A","-11862C","-11863T","-11864A","-11865G","-11866A","-11867G","-11868G","-11869G","-11870A","-11871T","-11872A","-11873T","-11874C","-11875G","-11876A","-11877T","-11878A","-11879T","-11880C","-11881G","-11882C","-11883C","-11884G","-11885A","-11886A","-11887T","-11888G","-11889T","-11890C","-11891A","-11892T","-11893A","-11894T","-11895A","-11896C","-11897T","-11898C","-11899A","-11900A","-11901T","-11902T","-11903A","-11904G","-11905T","-11906A","-11907T","-11908A","-11909T","-11910G","-11911T","-11912T","-11913G","-11914G","-11915A","-11916G","-11917G","-11918A","-11919C","-11920A","-11921T","-11922C","-11923C","-11924G","-11925A","-11926G","-11927T","-11928T","-11929C","-11930A","-11931T","-11932T","-11933G","-11934T","-11935T","-11936T","-11937T","-11938C","-11939A","-11940A","-11941T","-11942A","-11943T","-11944C","-11945A","-11946A","-11947A","-11948G","-11949A","-11950G","-11951A","-11952T","-11953G","-11954G","-11955T","-11956T","-11957T","-11958C","-11959C","-11960T","-11961T","-11962A","-11963T","-11964C","-11965A","-11966T","-11967T","-11968T","-11969C","-11970T","-11971C","-11972C","-11973A","-11974T","-11975A","-11976G","-11977T","-11978G","-11979G","-11980T","-11981A","-11982C","-11983A","-11984A","-11985T","-11986A","-11987C","-11988T","-11989A","-11990C","-11991A","-11992C","-11993A","-11994T","-11995T","-11996A","-11997T","-11998T","-11999C","-12000C","-12001G","-12002T","-12003A","-12004C","-12005G","-12006G","-12007C","-12008T","-12009T","-12010T","-12011C","-12012C","-12013A","-12014T","-12015T","-12016C","-12017T","-12018C","-12019C","-12020A","-12021A","-12022A","-12023A","-12024A","-12025C","-12026A","-12027A","-12028T","-12029T","-12030T","-12031T","-12032A","-12033C","-12034C","-12035A","-12036A","-12037A","-12038T","-12039C","-12040T","-12041A","-12042A","-12043A","-12044T","-12045C","-12046T","-12047A","-12048C","-12049A","-12050T","-12051C","-12052T","-12053T","-12054T","-12055A","-12056T","-12057T","-12058G","-12059T","-12060A","-12061T","-12062C","-12063T","-12064A","-12065T","-12066A","-12067A","-12068T","-12069C","-12070A","-12071C","-12072T","-12073A","-12074T","-12075T","-12076T","-12077A","-12078G","-12079A","-12080T","-12081A","-12082A","-12083T","-12084C","-12085A","-12086G","-12087C","-12088C","-12089A","-12090T","-12091A","-12092A","-12093T","-12094T","-12095C","-12096C","-12097T","-12098C","-12099G","-12100A","-12101G","-12102T","-12103G","-12104C","-12105A","-12106A","-12107C","-12108A","-12109T","-12110G","-12111T","-12112T","-12113A","-12114G","-12115A","-12116T","-12117C","-12118G","-12119T","-12120C","-12121T","-12122A","-12123T","-12124A","-12125T","-12126A","-12127T","-12128G","-12129A","-12130A","-12131T","-12132A","-12133A","-12134G","-12135C","-12136C","-12137G","-12138T","-12139G","-12140T","-12141T","-12142A","-12143T","-12144C","-12145T","-12146A","-12147T","-12148T","-12149C","-12150C","-12151T","-12152T","-12153T","-12154C","-12155A","-12156T","-12157T","-12158A","-12159A","-12160C","-12161A","-12162A","-12163T","-12164T","-12165T","-12166A","-12167A","-12168C","-12169G","-12170A","-12171T","-12172G","-12173T","-12174C","-12175T","-12176A","-12177T","-12178A","-12179T","-12180C","-12181T","-12182A","-12183T","-12184A","-12185T","-12186G","-12187A","-12188G","-12189A","-12190T","-12191G","-12192A","-12193C","-12194T","-12195T","-12196A","-12197A","-12198T","-12199A","-12200T","-12201A","-12202A","-12203T","-12204A","-12205T","-12206T","-12207G","-12208A","-12209A","-12210G","-12211A","-12212G","-12213C","-12214T","-12215G","-12216T","-12217A","-12218C","-12219A","-12220A","-12221T","-12222A","-12223G","-12224T","-12225T","-12226T","-12227T","-12228T","-12229A","-12230T","-12231C","-12232T","-12233A","-12234T","-12235A","-12236G","-12237A","-12238A","G40242A","C40335T","C127609T","G139582A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG023":["-222S","-223I","-224D","-225K","-226N","-227Y","-228C","-229T","-230A","-231L","-232Q","-233Y","-234Y","-235I","-236K","-237S","-238S","-239H","-240I","-241D","-242I","-243D","-244I","-245V","-246K","-247L","-248L","-249M","-250K","-251G","-252I","-253D","-254N","-255T","-256A","-257Y","-258S","-259Y","-260I","-261D","-262D","-263L","-264T","-265C","-266C","-267T","-268R","-269G","-270I","-271M","-272A","-273D","-274Y","-275L","-276N","-277S","-278D","-279Y","-280R","-281Y","-282N","-283K","-284D","-285V","-286D","-287L","-288D","-289L","-290V","-291K","-292L","-293F","-294L","-295E","-296N","-297G","-298K","-299P","-300Y","-301G","-302I","-303M","-304C","-305S","-306I","-307V","-308P","-309L","-310W","-311R","-312N","-313D","-314K","-315E","-316T","-317I","-318S","-319L","-320I","-321L","-322K","-323T","-324M","-325N","-326S","-327D","-328V","-329L","-330Q","-331H","-332I","-333L","-334I","-335E","-336Y","-337M","-338T","-339F","-340G","-341D","-342I","-343D","-344I","-345P","-346L","-347V","-348E","-349C","-350M","-351L","-352E","-353Y","-354G","-355A","-356V","-357V","-358N","-359K","-360E","-361A","-362I","-363H","-364R","-365Y","-366F","-367R","-368N","-369I","-370N","-371I","-372D","-373S","-374Y","-375T","-376M","-377K","-378Y","-379L","-380L","-381K","-382K","-383E","-384G","-385G","-386D","-387A","-388V","-389N","-390H","-391L","-392D","-393D","-394G","-395E","-396I","-397P","-398I","-399G","-400H","-401L","-402C","-403E","-404S","-405N","-406Y","-407G","-408C","-409Y","-410N","-411F","-412Y","-413T","-414Y","-415T","-416Y","-417K","-418K","-419G","-420L","-421C","-422D","-423M","-424S","-425Y","-426V","-427C","-428P","-429I","-430L","-431S","-432T","-433I","-434N","-435I","-436C","-437L","-438P","-439Y","-440L","-441K","-442D","-443I","-444N","-445M","-446I","-447D","-448K","-449R","-450G","-451E","-452T","-453L","-454L","-455H","-456K","-457A","-458V","-459R","-460Y","-461N","-462K","-463Q","-464S","-465L","-466V","-467S","-468L","-469L","-470L","-471E","-472S","-473G","-474S","-475D","-476V","-477N","-478I","-479R","-480S","-481N","-482N","-483G","-484Y","-485T","-486C","-487I","-488T","-489I","-490A","-491I","-492N","-493E","-494S","-495R","-496N","-497I","-498E","-499L","-500L","-501K","-502M","-503L","-504L","-505C","-506H","-507K","-508P","-509T","-510L","-511D","-512C","-513V","-514I","-515D","-516S","-517L","-518S","-519E","-520V","-521S","-522N","-523I","-524V","-525D"],"OPG058":["E34K"]},"labels":{"aa":"OPG023: -222S, -223I, -224D, -225K, -226N, -227Y, -228C, -229T, -230A, -231L, -232Q, -233Y, -234Y, -235I, -236K, -237S, -238S, -239H, -240I, -241D, -242I, -243D, -244I, -245V, -246K, -247L, -248L, -249M, -250K, -251G, -252I, -253D, -254N, -255T, -256A, -257Y, -258S, -259Y, -260I, -261D, -262D, -263L, -264T, -265C, -266C, -267T, -268R, -269G, -270I, -271M, -272A, -273D, -274Y, -275L, -276N, -277S, -278D, -279Y, -280R, -281Y, -282N, -283K, -284D, -285V, -286D, -287L, -288D, -289L, -290V, -291K, -292L, -293F, -294L, -295E, -296N, -297G, -298K, -299P, -300Y, -301G, -302I, -303M, -304C, -305S, -306I, -307V, -308P, -309L, -310W, -311R, -312N, -313D, -314K, -315E, -316T, -317I, -318S, -319L, -320I, -321L, -322K, -323T, -324M, -325N, -326S, -327D, -328V, -329L, -330Q, -331H, -332I, -333L, -334I, -335E, -336Y, -337M, -338T, -339F, -340G, -341D, -342I, -343D, -344I, -345P, -346L, -347V, -348E, -349C, -350M, -351L, -352E, -353Y, -354G, -355A, -356V, -357V, -358N, -359K, -360E, -361A, -362I, -363H, -364R, -365Y, -366F, -367R, -368N, -369I, -370N, -371I, -372D, -373S, -374Y, -375T, -376M, -377K, -378Y, -379L, -380L, -381K, -382K, -383E, -384G, -385G, -386D, -387A, -388V, -389N, -390H, -391L, -392D, -393D, -394G, -395E, -396I, -397P, -398I, -399G, -400H, -401L, -402C, -403E, -404S, -405N, -406Y, -407G, -408C, -409Y, -410N, -411F, -412Y, -413T, -414Y, -415T, -416Y, -417K, -418K, -419G, -420L, -421C, -422D, -423M, -424S, -425Y, -426V, -427C, -428P, -429I, -430L, -431S, -432T, -433I, -434N, -435I, -436C, -437L, -438P, -439Y, -440L, -441K, -442D, -443I, -444N, -445M, -446I, -447D, -448K, -449R, -450G, -451E, -452T, -453L, -454L, -455H, -456K, -457A, -458V, -459R, -460Y, -461N, -462K, -463Q, -464S, -465L, -466V, -467S, -468L, -469L, -470L, -471E, -472S, -473G, -474S, -475D, -476V, -477N, -478I, -479R, -480S, -481N, -482N, -483G, -484Y, -485T, -486C, -487I, -488T, -489I, -490A, -491I, -492N, -493E, -494S, -495R, -496N, -497I, -498E, -499L, -500L, -501K, -502M, -503L, -504L, -505C, -506H, -507K, -508P, -509T, -510L, -511D, -512C, -513V, -514I, -515D, -516S, -517L, -518S, -519E, -520V, -521S, -522N, -523I, -524V, -525D; OPG058: E34K"}},"children":[{"name":"OP431400","node_attrs":{"div":10,"accession":"OP431400","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-22751-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP431400/2022-08-17"},"date":{"value":"2022-08-17"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G47482A","C60062T","G125388A"],"OPG080":["E653K"],"OPG145":["R481H"]},"labels":{"aa":"OPG080: E653K; OPG145: R481H"}}},{"name":"OP390175","node_attrs":{"div":7,"accession":"OP390175","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"BOL-UNIMOL-MPX-292803-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"strain_display":{"value":"Colombia/OP390175/2022-08-02"},"date":{"value":"2022-08-02"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{}}},{"name":"OP819950","node_attrs":{"div":9,"accession":"OP819950","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MET_INS_MPX_0956_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP819950/2022-10-12"},"date":{"value":"2022-10-12"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G144284A","C171808T","-180517A","-180518A","-180519T","-180520G","-180521A","-180522C","-180523G","-180524A","-180525T","-180526A","-180527T","-180528A","-180529C","-180530G","-180531G","-180532A","-180533T","-180534T","G196973-","A196974-","A196975-"],"OPG165":["D257N"],"OPG199":["S274L"]},"labels":{"aa":"OPG165: D257N; OPG199: S274L"}}},{"name":"OP693654","node_attrs":{"div":7,"accession":"OP693654","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"DC_INS_MPX_0722_L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP693654/2022-08-23"},"date":{"value":"2022-08-23"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A2840-","T2841-","C2842-"]}}},{"name":"NODE_0000126","node_attrs":{"div":8,"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C21324T"]}},"children":[{"name":"OP623592","node_attrs":{"div":10,"accession":"OP623592","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"BOL-UNIMOL-MPX-293165-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"strain_display":{"value":"Colombia/OP623592/2022-08-09"},"date":{"value":"2022-08-09"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C18213T","G141921A"],"OPG031":["E206K"]},"labels":{"aa":"OPG031: E206K"}}},{"name":"OP837479","node_attrs":{"div":11,"accession":"OP837479","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"DC_INS_MPX_1024_L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP837479/2022-09-20"},"date":{"value":"2022-09-20"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","G68296A","C144166T","-180517A","-180518A","-180519T","-180520G","-180521A","-180522C","-180523G","-180524A","-180525T","-180526A","-180527T","-180528A","-180529C","-180530G","-180531G","-180532A","-180533T","-180534T","C181495T"],"OPG085":["S79L"],"OPG210":["S47L"]},"labels":{"aa":"OPG085: S79L; OPG210: S47L"}}},{"name":"OR035721","node_attrs":{"div":9,"accession":"OR035721","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_115"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035721/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-180517A","-180518A","-180519T","-180520G","-180521A","-180522C","-180523G","-180524A","-180525T","-180526A","-180527T","-180528A","-180529C","-180530G","-180531G","-180532A","-180533T","-180534T","G180556A","T196712-","A196713-","T196714-"]}}}]}]}]},{"name":"NODE_0000127","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C112408T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG131":["L157F"]},"labels":{"aa":"OPG131: L157F"}},"children":[{"name":"OQ672571","node_attrs":{"div":3,"accession":"OQ672571","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"19012023_anal"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672571/2023-01-19"},"date":{"value":"2023-01-19"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G69989A","C117978T","T145510-","T145511-","A145512-","C145513-","T145514-","T145515-","A145516-","A145517-","T145518-","A145519-","G145520-","A145521-","T145522-","T145523-","A145524-","T145525-","G145526-","T145527-","T146786-","A146787-","T146788-","T146789-","G146790-","T146791-","T146792-","A146793-","T146794-","C146795-","G146796-","T146797-","A146798-","A146799-","T146800-","T146801-","G146802-","G146803-","A146804-","A146805-","A146806-","A146807-","T146808-","T146809-","G146810-","G146811-","T146812-","A146813-","T146814-","T146815-","C146816-","A146817-","A146818-","G146819-","T146820-","G146821-","A146822-","G146823-","C146824-","T146825-","G146826-","G146827-","A146828-","T146829-","T146830-","A146831-","T146832-","G146833-","T146834-","G146835-","A146836-","G146837-","T146838-","A146839-","T146840-","T146841-","G146842-","G146843-","A146844-","T146845-","T146846-","G146847-","T146848-","A146849-","T146850-","A146851-","T146852-","T146853-","T146854-","T146855-","A146856-","T146857-","T146858-","T146859-","T146860-","A146861-","T146862-","A146863-","T146864-","T146865-","T146866-","T146867-","A146868-","T146869-","A146870-","T146871-","T146872-","T146873-","T146874-","A146875-","T146876-","A146877-","T146878-","T146879-","T146880-","T146881-","A146882-","T146883-","T146884-","T146885-","T146886-","A146887-","T146888-","A146889-","T146890-","T146891-","T146892-","T146893-","A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","G146913-","T146914-","A146915-","G146916-","T146917-","A146918-","A146919-","G146920-","A146921-","A146922-","T146923-","A146924-","G146925-","A146926-","A146927-","T146928-","G146929-","C146930-","T146931-","A146932-","A146933-","T146934-","G146935-","T146936-","C146937-","A146938-","A146939-","G146940-","T146941-","T146942-","T146943-","A146944-","T146945-","T146946-","C146947-","G146948-","A146949-","A146950-","T146951-","A146952-","G146953-","A146954-","T146955-","G146956-","T146957-","C146958-","T146959-","T146960-","A146961-","T146962-","T146963-","A146964-","A146965-","A146966-","A146967-","A146968-","A146969-","C146970-","A146971-","T146972-","A146973-","T146974-","A146975-","T146976-","A146977-","A146978-","T146979-","A146980-","A146981-","A146982-","T146983-","A146984-","A146985-","C146986-","A146987-","A146988-","T146989-","G146990-","G146991-","C146992-","T146993-","G146994-","A146995-","A146996-","T146997-","G146998-","G146999-","C147000-","A147001-","T147002-","A147003-","A147004-","A147005-","A147006-","T147007-","T147008-","A147009-","T147010-","C147011-","G147012-","A147013-","G147014-","G147015-","A147016-","T147017-","A147018-","T147019-","C147020-","T147021-","C147022-","A147023-","A147024-","A147025-","A147026-","A147027-","T169726-","A169727-"],"OPG089":["A42T"],"OPG136":["R537K"],"OPG197":["T20-"]},"labels":{"aa":"OPG089: A42T; OPG136: R537K; OPG197: T20-"}}},{"name":"NODE_0000128","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G6878A","C40894T","C67724T","C145201-","C145202-","A145203-","T145204-","T145205-","T145206-","A145207-","T180382-","A180383-","T180384-","T180385-","A180386-","C180387-","A180388-","A180389-","A180390-","T180391-","A180392-","G180393-","T180394-","A180395-","T180396-","A180397-","G180398-","C180399-","A180400-","T180401-","A180402-","A180403-","A180404-","C180405-","T180406-","A180407-","A180408-","A180409-","G180410-","T180411-","C180412-","G180413-","A180414-","T180415-","A180416-","C180417-","A180418-","T180419-","A180420-","C180421-","A180422-","T180423-","T180424-","A180425-","A180426-","A180427-","A180428-","C180429-","T180430-","T180431-","A180432-","A180433-","A180434-","T180435-","A180436-","A180437-","T180438-","A180439-","A180440-","T180441-","G180442-","T180443-","A180444-","A180445-","T180446-","T180447-","T180448-","A180449-","C180450-","A180451-","A180452-","T180453-","T180454-","A180455-","A180456-","T180457-","A180458-","G180459-","T180460-","A180461-","T180462-","A180463-","A180464-","A180465-","C180466-","T180467-","A180468-","A180469-","A180470-","A180471-","A180472-","A180473-","A180474-","T180475-","T180476-","A180477-","A180478-","A180479-","A180480-","A180481-","A180482-","T180483-","T180484-","A180485-","A180486-","A180487-","A180488-","A180489-","C180490-","A180491-","A180492-","T180493-","A180494-","T180495-","C180496-","A180497-","T180498-","T180499-","A180500-","T180501-","T180502-","A180503-","T180504-","A180505-","A180506-","G180507-","T180508-","A180509-","A180510-","T180511-","A180512-","T180513-","C180514-","A180515-","A180516-","A180535-","A180536-","T180537-","A180538-","G180539-","C180540-","G180541-","T180542-","A180543-","T180544-","C180545-","T180546-","T180547-","A180548-","T180549-","A180550-","T180551-","T180552-","C180553-","G180554-","T180555-","G180556-","A180557-","C180558-","T180559-","T180560-","C180561-","A180562-","T180563-","C180564-","C180565-","A180566-","T180567-","C180568-","G180569-","C180570-","T180571-","A180572-","G180573-","T180574-","C180575-","C180576-","A180577-","C180578-","T180579-","T180580-","T180581-","A180582-","C180583-","A180584-","T180585-","T180586-","C180587-","C180588-","C180589-","G180590-","T180591-","T180592-","A180593-","T180594-","T180595-","C180596-","C180597-","G180598-","C180599-","C180600-","C180601-","A180602-","T180603-","T180604-","T180605-","C180606-","G180607-","G180608-","A180609-","A180610-","G180611-","A180612-","T180613-","A180614-","A180615-","A180616-","T180617-","C180618-","G180619-","T180620-","T180621-","C180622-","A180623-","A180624-","T180625-","A180626-","G180627-","T180628-","G180629-","T180630-","A180631-","G180632-","A180633-","G180634-","G180635-","T180636-","A180637-","T180638-","T180639-","A180640-","G180641-","T180642-","T180643-","T180644-","C180645-","T180646-","T180647-","T180648-","G180649-","T180650-","T180651-","T180652-","C180653-","C180654-","C180655-","G180656-","A180657-","T180658-","G180659-","A180660-","C180661-","C180662-","A180663-","A180664-","A180665-","A180666-","A180667-","G180668-","A180669-","C180670-","T180671-","A180672-","T180673-","A180674-","C180675-","A180676-","G180677-","T180678-","A180679-","A180680-","C180681-","T180682-","T180683-","C180684-","T180685-","C180686-","A180687-","G180688-","T180689-","T180690-","C180691-","A180692-","A180693-","T180694-","A180695-","A180696-","C180697-","T180698-","A180699-","C180700-","A180701-","C180702-","T180703-","A180704-","T180705-","C180706-","G180707-","G180708-","T180709-","A180710-","C180711-","C180712-","A180713-","A180714-","A180715-","G180716-","A180717-","C180718-","T180719-","G180720-","G180721-","A180722-","C180723-","T180724-","A180725-","T180726-","C180727-","A180728-","A180729-","C180730-","G180731-","T180732-","A180733-","C180734-","T180735-","A180736-","T180737-","C180738-"],"OPG060":["G97R"],"OPG085":["E270K"],"OPG167":["K68-","W69-"]},"labels":{"aa":"OPG060: G97R; OPG085: E270K; OPG167: K68-, W69-"}},"children":[{"name":"OQ672575","node_attrs":{"div":6,"accession":"OQ672575","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"02022023_gluteal"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672575/2023-02-02"},"date":{"value":"2023-02-02"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["A125538G","G152986A"],"OPG180":["E99K"]},"labels":{"aa":"OPG180: E99K"}}},{"name":"OQ672573","node_attrs":{"div":5,"accession":"OQ672573","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"26012023_neck"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672573/2023-01-26"},"date":{"value":"2023-01-26"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","T2653-","T2654-","T47709-","G47710-","T47742-","T47743-","A47744-","G47745-","G47746-","A47747-","C47748-","T47749-","A47750-","C47751-","T47752-","A47753-","C47754-","T47755-","C47756-","T47757-","A47758-","G47759-","A47760-","A47761-","G47762-","A47763-","T47764-","A47765-","T47766-","A47767-","G47768-","C47769-","A47770-","C47771-","C47772-","A47773-","T47774-","C47775-","T47776-","A47777-","T47778-","T47779-","C47780-","C47781-","A47782-","A47783-","A47784-","T47785-","A47786-","A47787-","T47788-","C47789-","A47790-","G47791-","A47792-","A47793-","A47794-","A47795-","C47796-","T47797-","T47798-","A47799-","T47800-","A47801-","A47802-","A47803-","C47804-","T47805-","A47806-","T47807-","T47808-","C47809-","T47810-","C47811-","G47812-","G47813-","A47814-","C47815-","A47816-","T47817-","T47818-","T47819-","C47820-","A47821-","G47822-","T47823-","C47824-","A47825-","T47826-","T47827-","G47828-","G47829-","C47830-","A47831-","A47960-","T47961-","G47962-","T47963-","A47964-","T47965-","G47966-","C47967-","C47968-","T47969-","G47970-","T47971-","T47972-","C47973-","G47974-","T47975-","A47976-","T47977-","G47978-","C47979-","C47980-","A48037-","G48038-","T48039-","C48069-","A48070-","T48071-","C48072-","A48113-","T48114-","A48115-","G48116-","T48117-","A48118-","C48176-","A48177-","T48178-","A48179-","G48180-","A48181-","T48182-","A48183-","A48184-","C48185-","T48186-","C48187-","T48188-","C48189-","T48190-","T48191-","C48192-","T48193-","A48194-","T48195-","A48196-","A48197-","A48198-","A48199-","A48200-","A48201-","T48202-","G48203-","G48204-","A48205-","T48206-","T48207-","T48208-","T48209-","A48210-","T48211-","T48212-","C48213-","G48214-","T48215-","A48216-","G48217-","A48218-","A48219-","A48220-","G48221-","T48222-","A48223-","T48224-","C48225-","T48226-","T48227-","A48228-","T48229-","A48230-","T48231-","A48232-","C48233-","A48234-","C48235-","A48236-","G48237-","T48238-","A48239-","G48240-","A48241-","A48289-","T48290-","A48330-","G48331-","C48332-","A48333-","A48334-","T48335-","T48336-","T48337-","T48338-","C48339-","T48366-","G48387-","T48388-","T48389-","T48390-","T48391-","C48392-","A48393-","T48394-","A48395-","C48396-","A48397-","C48435-","G48436-","A48437-","C48438-","A48439-","C48440-","G48441-","C48442-","A48443-","T48444-","T48445-","T48446-","G48447-","A48448-","T48449-","G48450-","C48451-","A48452-","A48571-","A48572-","T48573-","A48574-","C48575-","A48576-","T48577-","G48578-","G48579-","A48580-","C48581-","G48582-","A48583-","A48584-","T48585-","T48586-","A48587-","G48588-","G48589-","A48590-","G48591-","A48592-","A48593-","C48594-","T48595-","T48596-","A48597-","T48598-","A48599-","G48600-","G48601-","C48602-","G48603-","T48604-","A48605-","A48606-","A48607-","T48608-","T48609-","A48610-","T48611-","G48612-","A48613-","C48614-","T48615-","T48616-","A48617-","G48618-","T48619-","C48648-","C48649-","C48650-","A48651-","T48652-","C48653-","A48654-","A48655-","A48656-","G48657-","A48658-","T48659-","A48660-","T48661-","G48662-","G48663-","A48664-","A48665-","A48666-","T48667-","C48668-","A48669-","T48670-","T48671-","T48672-","T48673-","T48674-","A48759-","A48760-","A48761-","G48762-","A48763-","T48764-","A48765-","C48766-","A48767-","G48768-","G48769-","C48770-","A48771-","T48772-","A48773-","G48774-","G48780-","C48781-","G48782-","G48783-","A48784-","T48785-","A48786-","A48787-","T48788-","G48789-","A48790-","T48791-","A48792-","G48793-","A48794-","C48823A","C48837-","A48838-","T48839-","A48840-","G48841-","C48842-","A48843-","A48844-","T48845-","C48846-","T48847-","A48848-","A48849-","C48850-","A48851-","G48852-","A48853-","A48854-","A48855-","C48856-","G48857-","T48858-","T48859-","T48860-","A48861-","G48862-","G48863-","G48864-","A48865-","T48866-","T48867-","A48868-","T48869-","A48870-","T48871-","C48872-","T48873-","T48874-","T48875-","C48876-","C48877-","C48878-","G48879-","G48880-","A48881-","G48882-","A48883-","T48884-","A48885-","A48886-","G48887-","A48888-","C48889-","A48924-","A48925-","T48926-","G48927-","A48928-","T48929-","G48930-","C48931-","G48932-","G48933-","A48934-","A48987-","T48988-","A48989-","T48990-","A48991-","C48992-","T48993-","C48994-","T48995-","G48996-","A48997-","G48998-","A48999-","T49000-","A49001-","A49002-","A49003-","A49004-","C49005-","A49006-","G49007-","G49008-","G49009-","A49010-","C49011-","G49012-","C49013-","G49014-","T49015-","T49016-","A49017-","A49018-","T49019-","A49020-","A49021-","A49022-","A49023-","A49024-","C49025-","A49026-","T49027-","G49028-","C49029-","T49030-","T49031-","A49032-","A49033-","G49034-","T49035-","T49036-","A49037-","G49038-","T49039-","T49040-","T49041-","A49042-","T49043-","A49044-","T49045-","C49046-","T49047-","T49048-","T49049-","G49050-","A49051-","G49052-","C49053-","C49054-","T49157-","A49158-","T49159-","T49160-","A49161-","G49162-","T49163-","T49164-","T49165-","T49166-","T49167-","A49168-","C49169-","A49170-","A49171-","A49172-","G49173-","C49174-","T49175-","A49176-","A49177-","T49178-","T49179-","T49180-","T49181-","A49182-","T49183-","T49184-","A49185-","A49186-","C49187-","G49188-","G49189-","T49190-","A49191-","A49192-","T49193-","A49194-","C49195-","A49196-","T49197-","T49198-","T49199-","A49200-","T49201-","T49202-","A49203-","G49204-","T49205-","G49206-","A49207-","T49208-","A49209-","G49210-","A49211-","A49212-","C49213-","G49214-","T49215-","T49216-","T49217-","A49218-","A49219-","C49220-","G49221-","A49222-","T49223-","G49224-","A49225-","C49226-","T49227-","T49228-","A49229-","T49230-","T49231-","C49232-","A49233-","G49234-","A49235-","G49236-","T49237-","T49238-","G49239-","T49240-","T49241-","G49242-","T49243-","T49244-","C49245-","A49246-","A49247-","A49248-","T49249-","A49250-","G49251-","A49252-","T49253-","C49254-","C49255-","C49256-","G49257-","A49258-","A49259-","T49260-","A49261-","T49262-","T49263-","T49264-","C49265-","G49266-","A49267-","T49268-","A49269-","A49270-","T49271-","G49272-","A49273-","A49274-","C49275-","G49276-","A49277-","A49278-","T49279-","T49280-","A49281-","T49282-","G49283-","T49284-","C49285-","T49286-","T49287-","T49288-","A49289-","T49290-","T49291-","C49292-","T49293-","A49294-","T49295-","A49296-","C49297-","G49298-","A49299-","G49300-","T49301-","G49302-","C49303-","T49304-","G49305-","C49306-","G49307-","G49308-","A49309-","C49310-","A49311-","T49312-","T49313-","A49314-","A49315-","A49316-","C49317-","G49318-","A49319-","T49320-","T49321-","T49322-","G49323-","A49324-","T49325-","G49326-","A49327-","G49328-","T49329-","T49330-","A49331-","G49332-","A49333-","T49334-","A49335-","T49336-","T49337-","A49338-","A49339-","T49340-","A49341-","A49342-","C49343-","A49344-","G49345-","T49346-","T49347-","A49348-","T49349-","A49350-","T49351-","A49352-","T49353-","C49354-","T49355-","A49356-","A49357-","T49358-","A49407-","A49408-","G49409-","A49410-","A49411-","G49412-","T49413-","G49414-","T49415-","C49416-","A49417-","A49418-","A49419-","T49420-","T49473-","T49474-","G49475-","C49476-","A49477-","C49478-","G49479-","A49480-","G49481-","T49482-","C49483-","G49484-","G49485-","A49486-","T49487-","C49488-","C49489-","C49490-","A49491-","T49492-","G49493-","G49494-","T49495-","C49496-","A49497-","T49498-","A49499-","G49500-","A49501-","G49502-","A49503-","A49504-","C49505-","G49506-","G49507-","A49508-","A49509-","T49510-","A49511-","C49512-","T49513-","A49514-","A49515-","A49516-","G49517-","A49518-","A49519-","A49520-","C49521-","T49522-","G49523-","T49524-","C49525-","A49526-","T49527-","C49528-","T49529-","A49530-","T49531-","A49532-","A49533-","A49534-","A49535-","T49536-","C49537-","C49538-","A49539-","A49540-","G49541-","A49542-","G49543-","T49544-","A49545-","G49546-","A49547-","C49548-","G49549-","G49550-","C49551-","T49552-","G49553-","A49554-","A49555-","C49556-","T49557-","T49558-","G49559-","T49560-","T49561-","T49562-","A49563-","G49564-","C49565-","A49566-","A49567-","A49568-","A49569-","A49570-","C49571-","A49572-","T49573-","T49574-","T49575-","T49576-","A49577-","A49578-","A49579-","A49580-","T49581-","A49582-","T49583-","T49584-","A49585-","T49586-","T49587-","T49588-","A49589-","G49590-","A49591-","C49592-","G49593-","G49594-","A49595-","C49596-","A49597-","A49598-","T49599-","T49600-","G49601-","G49602-","C49603-","T49604-","C49605-","G49606-","T49607-","C49608-","T49609-","A49610-","G49611-","G49612-","T49613-","C49614-","T49615-","T49616-","G49617-","T49618-","G49619-","T49620-","T49621-","A49622-","G49623-","A49624-","T49625-","G49626-","A49627-","T49628-","T49629-","A49630-","T49631-","A49632-","A49633-","A49634-","G49635-","G49636-","A49637-","G49638-","A49639-","C49640-","T49641-","T49642-","A49643-","T49644-","T49645-","A49646-","G49647-","T49648-","T49649-","A49650-","A49651-","A49652-","A49653-","T49654-","G49655-","A49656-","T49657-","A49658-","A49659-","A49660-","C49661-","C49662-","A49663-","T49664-","C49665-","T49666-","C49667-","A49668-","A49669-","A49670-","T49671-","C49672-","T49673-","G49674-","T49675-","G49676-","G49677-","A49678-","G49679-","G49680-","A49681-","T49682-","G49683-","T49684-","A49685-","T49686-","C49687-","C49688-","G49689-","C49690-","A49691-","T49692-","T49693-","C49694-","G49695-","T49696-","T49697-","A49698-","G49699-","A49700-","T49701-","T49702-","T49703-","T49704-","C49705-","T49706-","A49707-","C49708-","A49709-","A62259-","G62260-","T62261-","T62262-","A62263-","C62305-","A62306-","A62307-","A62308-","G62309-","A62328-","G62329-","T62330-","T62331-","G62332-","T62333-","A62334-","T62335-","A62336-","C62337-","T62338-","G62339-","A62340-","G62341-","A62342-","A62343-","T62344-","T62345-","G62346-","A62347-","C62348-","G62349-","T62373-","T62374-","T62375-","C62376-","T62377-","A62412-","C62413-","T62414-","A62415-","G62416-","A62417-","C62418-","T62419-","T62420-","G62421-","A62422-","A62433-","G62434-","T62435-","A62436-","T62437-","A62438-","G62439-","A62535-","C62536-","G62552-","A62553-","G62554-","G62571-","C62572-","T62573-","T62574-","C62575-","T62576-","A62577-","G62578-","A62601-","C62624-","T62625-","A62626-","T62627-","C62628-","A62646-","C62647-","T62648-","C62649-","G62650-","C62651-","G62652-","T62653-","T62654-","T62655-","A62656-","G62657-","A62658-","G62659-","G62660-","A62661-","G62662-","T62663-","G62664-","A62665-","A62666-","C62667-","G62668-","T62669-","C62670-","T62671-","T62672-","C62673-","G62758-","T62759-","G62760-","G62761-","A62762-","A62763-","T62764-","T62765-","G62766-","A62767-","A62768-","G62769-","A62770-","T62771-","T62772-","C62773-","T62774-","A62775-","A62776-","T62777-","G62778-","G62779-","A62780-","T62781-","G62782-","A62783-","T62784-","G62785-","T62786-","T62787-","C62788-","T62789-","A62790-","C62791-","C62792-","T62793-","A62794-","T62795-","T62796-","T62797-","C62798-","A62799-","T62800-","C62801-","C62802-","G62803-","A62804-","T62805-","C62820-","A62821-","A62822-","T62823-","T62856-","A62857-","G62858-","T62859-","C62860-","T62861-","C62862-","T62863-","C62864-","T62865-","T62866-","T62867-","C62868-","G62869-","G62870-","A62871-","A62892-","T62893-","A62894-","C62895-","G62896-","A62897-","G62898-","T62899-","C62900-","A62901-","T62902-","T62903-","A62904-","T62905-","A62906-","T62907-","A62908-","C62909-","T62910-","C62911-","C62912-","T62931-","T62949-","G62950-","G62951-","G62952-","A62953-","C62967-","G62968-","A62969-","T62970-","A62982-","T62983-","C62984-","C62985-","G62986-","G62987-","A62988-","A62989-","C62990-","A62991-","T62992-","T62993-","G62994-","G63024-","G63025-","T63026-","A63027-","A63028-","G63029-","A63030-","A63031-","C63032-","A63042-","T63075-","T63076-","G63077-","A63078-","G63079-","A63080-","C63081-","T63082-","T63083-","G63084-","A63085-","T63086-","A63102-","T63103-","T63104-","C63143-","G63144-","T63145-","C63146-","G63147-","A63148-","C63149-","G63150-","C63151-","C63152-","A63153-","T63168-","G63169-","G63170-","A63171-","G63172-","T63173-","A63174-","C63240-","T63241-","C63242-","G63243-","T63244-","A63245-","C63246-","G63247-","C63248-","C63258-","A63259-","T63260-","G63261-","A63262-","T63263-","C63264-","A63265-","A63266-","G63267-","A63268-","G63269-","T63270-","G63271-","A63272-","T63273-","T63274-","T63275-","G63276-","A63277-","G63278-","A63279-","A63280-","C63281-","A63282-","T63283-","C63284-","C63285-","T63286-","C63287-","C63288-","A63311-","C63312-","A63313-","G63314-","T63315-","A63330-","T63331-","A63332-","A63333-","A63348-","A63349-","T63369-","A63370-","A63371-","A63372-","G63373-","A63374-","T63375-","T63385-","C63386-","T63387-","A63388-","A63389-","C63390-","G63391-","G63392-","A63393-","G63394-","A63395-","C63396-","A63397-","A63398-","T63399-","T63400-","T63401-","T63402-","T63403-","T63404-","G63405-","G63406-","T63407-","A63408-","G63409-","G63410-","T63411-","T63412-","T63413-","T63414-","A63415-","G63416-","A63417-","G63418-","A63419-","C63420-","T63421-","T63422-","T63423-","G63424-","A63425-","A63426-","G63427-","C63428-","T63429-","A63430-","C63431-","T63432-","T63433-","G63434-","T63435-","T63436-","T63437-","A63438-","A63439-","C63440-","A63441-","A63442-","A63443-","G63444-","T63445-","T63446-","A63447-","T63448-","T63449-","C63450-","A63451-","T63452-","C63453-","G63454-","T63455-","C63456-","T133098-","T133099-","T133100-","T133101-","T133102-","C180739-","A180740-"],"OPG002":["D34-","N35-"],"OPG068":["S44-","N45-","F46-","P47-","Q48-","H49-","L56-","V63-","F64-","I65-","H66-","M67-","V68-","R69-","H80-","A81-","F82-","D83-","A84-","P85-","Y125-","M126-","D127-","E128-","L129-","G130-","E131-","L132-","I133-","G134-","V135-","N136-","Y137-","D138-","L139-","V140-","N242-","D243-","A244-","D245-","I263-","Y264-","S265-","E266-","I267-","K268-","Q269-","G270-","R271-","V272-","N273-","K274-","N275-","M276-","L277-","K278-","L279-","V280-","Y281-","I282-","F283-","E284-","P285-","I320-","S321-","F322-","Y323-","K324-","A325-","N326-","F327-","I328-","N329-","G330-","N331-","T332-","F333-","I334-","S335-","D336-","R337-","T338-","F339-","N340-","D341-","D342-","L343-","F344-","R345-","V346-","V347-","V348-","Q349-","I350-","D351-","P352-","E353-","Y354-","F355-","D356-","N357-","E358-","R359-","I360-","M361-","S362-","L363-","F364-","Y365-","T366-","S367-","A368-","A369-","D370-","I371-","K372-","R373-","F374-","D375-","E376-","L377-","D378-","I379-","N380-","N381-","S382-","Y383-","I384-","S385-","N386-","I387-","K403-","K404-","C405-","Q406-","I407-"],"OPG081":["T9-"],"OPG082":["S27-","L28-","Y41-","L47-","F48-","T49-","K50-","E56-","D57-","V58-","L59-","K60-","S61-","L62-","L63-","I64-","M65-","N154-","V155-","P156-","D157-","S158-","S162-","P168-","F169-","D170-","L211-","E212-","I213-","N214-","M215-","L216-","S217-","D218-","E219-","I220-","G221-","R222-","T223-","S224-","S225-","I226-","R227-","I228-","F229-","S231M","T232F","K261-","T262-","F263-","T264-","P265-","L266-","N267-","A268-","S269-","I276-","V277-","R293-","S294-","T300N","H301-","Y339-","T340-","K345-","S346-","S347-"]},"labels":{"aa":"OPG002: D34-, N35-; OPG068: S44-, N45-, F46-, P47-, Q48-, H49-, L56-, V63-, F64-, I65-, H66-, M67-, V68-, R69-, H80-, A81-, F82-, D83-, A84-, P85-, Y125-, M126-, D127-, E128-, L129-, G130-, E131-, L132-, I133-, G134-, V135-, N136-, Y137-, D138-, L139-, V140-, N242-, D243-, A244-, D245-, I263-, Y264-, S265-, E266-, I267-, K268-, Q269-, G270-, R271-, V272-, N273-, K274-, N275-, M276-, L277-, K278-, L279-, V280-, Y281-, I282-, F283-, E284-, P285-, I320-, S321-, F322-, Y323-, K324-, A325-, N326-, F327-, I328-, N329-, G330-, N331-, T332-, F333-, I334-, S335-, D336-, R337-, T338-, F339-, N340-, D341-, D342-, L343-, F344-, R345-, V346-, V347-, V348-, Q349-, I350-, D351-, P352-, E353-, Y354-, F355-, D356-, N357-, E358-, R359-, I360-, M361-, S362-, L363-, F364-, Y365-, T366-, S367-, A368-, A369-, D370-, I371-, K372-, R373-, F374-, D375-, E376-, L377-, D378-, I379-, N380-, N381-, S382-, Y383-, I384-, S385-, N386-, I387-, K403-, K404-, C405-, Q406-, I407-; OPG081: T9-; OPG082: S27-, L28-, Y41-, L47-, F48-, T49-, K50-, E56-, D57-, V58-, L59-, K60-, S61-, L62-, L63-, I64-, M65-, N154-, V155-, P156-, D157-, S158-, S162-, P168-, F169-, D170-, L211-, E212-, I213-, N214-, M215-, L216-, S217-, D218-, E219-, I220-, G221-, R222-, T223-, S224-, S225-, I226-, R227-, I228-, F229-, S231M, T232F, K261-, T262-, F263-, T264-, P265-, L266-, N267-, A268-, S269-, I276-, V277-, R293-, S294-, T300N, H301-, Y339-, T340-, K345-, S346-, S347-"}}}]},{"name":"NODE_0000129","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G47746-","A62110-","T62111-","A62112-","A62113-","A62114-","A62116-","T62118-","T62121-","A62122-","T62123-","A62124-","T62125-","A62126-","T62127-","T62128-","T62129-","A62131-","A62132-","A62133-","A62134-","T62135-","T62138-","T62139-","A62140-","T62144-","T62145-","A62148-","T62149-","T62150-","A62151-","A62167-","T62168-","T62169-","T62171-","A62173-","A62174-","T62175-","A62176-","T62177-","A62178-","T62179-","A62181-","T62182-","T62183-","A62184-","A62187-","T62188-","T62189-","T62190-","A62191-","A62192-","T62194-","T62197-","T62198-","A62200-","T62202-","A62203-","T62204-","A62206-","T62207-","T62213-","A62217-","A62219-","A62220-","A62221-","T62222-","T62223-","A62224-","A62227-","T62228-","A62230-","A62231-","A62232-","A62233-","A62236-","T62237-","T62238-","A62239-","A62240-","T62241-","A62242-","A62244-","T62246-","T62247-","A62248-","T62249-","A62252-","A62254-","T62255-","A62259-","T62261-","T62262-","A62263-","A62265-","A62266-","T62270-","T62271-","A62272-","T62273-","A62274-","A62277-","T62278-","A62281-","A62284-","T62285-","T62286-","T62287-","A62288-","T62289-","A62290-","T62291-","T62293-","A62294-","A62295-","A62296-","A62297-","A62298-","T62299-","T62300-","A62301-","A62303-","T62304-","A62306-","A62307-","A62308-","A62310-","A62311-","T62312-","A62313-","T62314-","T62316-","A62318-","A62320-","A62321-","T62324-","T62327-","A62328-","T62330-","T62331-","T62333-","A62334-","T62335-","A62336-","T62338-","A62340-","A62342-","A62343-","T62344-","T62345-","A62347-","A62350-","A62351-","A62352-","A62354-","A62355-","T62356-","T62358-","T62359-","T62360-","T62362-","T62363-","A62364-","A62366-","T62367-","A62368-","T62369-","T62370-","T62371-","T62372-","T62373-","T62374-","T62375-","T62377-","T62378-","A62379-","T62380-","T62381-","A62382-","T62384-","A62385-","A62386-","A62390-","T62392-","T62393-","A62394-","A62395-","T62396-","A62397-","T62399-","A62400-","A62403-","A62404-","T62406-","A62409-","A62410-","A62411-","A62412-","T62414-","A62415-","A62417-","T62419-","T62420-","A62422-","T62423-","T62424-","A62425-","T62426-","T62427-","T62429-","A62430-","T62431-","A62432-","A62433-","T62435-","A62436-","T62437-","A62438-","A62440-","T62441-","A62442-","T62446-","T62447-","A62450-","A62451-","A62452-","T62453-","A62454-","A62455-","T62456-","T62458-","T62459-","T62461-","T62463-","T62464-","T62465-","A62467-","T62468-","A62469-","A62470-","A62471-","A62472-","T62474-","T62475-","A62478-","A62480-","A62481-","A62482-","A62483-","T62484-","T62486-","A62487-","A62489-","A62490-","T62491-","T62492-","T62493-","T62494-","T62495-","T62496-","A62497-","A62498-","A62499-","A62500-","A62501-","T62503-","T62504-","A62505-","T62506-","T62508-","T62509-","T62510-","T62511-","T62514-","A62515-","T62516-","T62517-","A62518-","T62520-","A62521-","A62522-","T62523-","A62524-","T62525-","T62528-","T62531-","T62532-","A62533-","A62535-","T62539-","T62540-","A62541-","T62542-","T62543-","A62544-","T62545-","T62546-","A62547-","A62548-","T62549-","A62550-","T62551-","A62553-","T62555-","A62557-","T62558-","A62560-","A62561-","A62562-","T62563-","A62566-","A62568-","T62573-","T62574-","T62576-","A62577-","A62579-","T62580-","A62581-","T62582-","T62586-","T62587-","T62588-","T62589-","A62590-","T62591-","T62592-","T62593-","A62596-","A62598-","T62599-","T62600-","A62601-","A62603-","T62604-","T62607-","A62608-","A62609-","A62610-","T62611-","A62614-","A62615-","T62616-","A62617-","T62619-","A62621-","A62622-","A62623-","T62625-","A62626-","T62627-","T62629-","T62630-","A62703-","T62704-","A62705-","A62706-","A62707-","A62709-","A62710-","T62711-","T62712-","T62713-","A62715-","A62717-","A62718-","A62719-","T62720-","A62723-","T62724-","T62726-","T62727-","A62728-","A62729-","T62730-","T62732-","A62733-","T62734-","T62735-","A62736-","T62738-","A62739-","A62742-","A62743-","A62744-","T62745-","T62746-","T62747-","T62748-","T62749-","T62750-","A62752-","T62756-","A62757-","T62759-","A62762-","A62763-","T62764-","T62765-","A62767-","A62768-","A62770-","T62771-","T62772-","T62774-","A62775-","A62776-","T62777-","A62780-","T62781-","A62783-","T62784-","T62786-","T62787-","T62789-","A62790-","T62793-","A62794-","T62795-","T62796-","T62797-","A62799-","T62800-","A62804-","T62805-","A62806-","A62807-","A62809-","T62810-","T62812-","T62813-","A62814-","A62815-","T62816-","T62817-","T62818-","A62821-","A62822-","T62823-","A62824-","A62827-","A62828-","T62832-","T62833-","T62834-","T62835-","A62836-","A62837-","T62838-","A62839-","T62840-","T62841-","T62842-","A62845-","T62846-","A62848-","T62849-","A62850-","T62851-","A62852-","T62856-","A62857-","T62859-","T62861-","C62862-","T62863-","T62865-","T62866-","T62867-","A62871-","T62873-","T62874-","A62875-","T62876-","A62877-","T62878-","A62879-","T62882-","T62883-","A62884-","T62885-","T62886-","A62889-","A62891-","A62892-","T62893-","A62894-","A62897-","T62899-","A62901-","T62902-","T62903-","A62904-","T62905-","A62906-","T62907-","A62908-","T62910-","A62913-","A62914-","A62915-","A62916-","A62917-","A62918-","A62920-","A62921-","A62922-","A62923-","T62924-","A62925-","A62926-","T62928-","A62929-","T62931-","A62932-","T62933-","A62934-","A62935-","A62936-","A62937-","T62938-","T62940-","T62942-","A62943-","T62944-","A62947-","A62948-","T62949-","A62953-","A62954-","A62955-","A62956-","A62957-","A62960-","A62961-","A62962-","T62963-","T62964-","A62965-","T62966-","A62969-","T62970-","A62971-","T62972-","A62973-","T62976-","A62977-","T62978-","A62979-","A62981-","A62982-","T62983-","A62988-","A62989-","A62991-","T62992-","T62993-","A62995-","A62996-","T62999-","A63000-","T63001-","T63002-","A63003-","A63004-","T63005-","A63006-","T63008-","T63009-","A63010-","A63011-","T63012-","T63013-","T63015-","T63016-","T63017-","T63018-","T63019-","A63021-","T63023-","T63026-","A63027-","A63028-","A63030-","A63031-","A63035-","T63036-","A63037-","T63040-","T63041-","A63042-","T63043-","T63044-","A63046-","A63048-","T63049-","T63050-","T63052-","A63053-","T63054-","T63057-","T63058-","T63059-","T63060-","A63061-","A63062-","A63063-","T63064-","A63065-","T63066-","T63067-","T63069-","A63070-","T63071-","A63072-","A63073-","T63075-","T63076-","A63078-","A63080-","T63082-","T63083-","A63085-","T63086-","A63087-","A63089-","T63090-","A63091-","T63092-","T63093-","A63094-","A63095-","T63096-","A63098-","A63101-","A63102-","T63103-","T63104-","A63106-","A63107-","A63108-","A63109-","T63110-","T63111-","A63112-","T63113-","T63114-","T63115-","T63116-","T63117-","A63118-","T63119-","A63121-","A63124-","T63127-","T63129-","T63131-","T63132-","T63133-","A63135-","A63138-","T63139-","A63141-","T63142-","T63145-","A63148-","A63153-","T63155-","T63156-","A63157-","A63158-","A63161-","A63162-","A63166-","A63167-","T63168-","A63171-","T63173-","A63174-","A63175-","A63176-","A63177-","T63178-","A63179-","A63180-","A63181-","T63182-","A63183-","T63184-","A63186-","T63187-","T63188-","A63189-","A63190-","T63191-","A63192-","T63193-","A63194-","T63195-","T63198-","T63200-","A63201-","A63203-","T63204-","A63205-","T63206-","T63207-","A63208-","T63210-","A63211-","T63212-","T63213-","T63214-","T63215-","T63216-","A63217-","T63218-","T63219-","A63220-","A63221-","T63222-","T63225-","T63226-","T63227-","A63229-","T63230-","T63231-","A63232-","T63233-","A63235-","T63236-","T63238-","T63239-","T63241-","T63244-","A63245-","A63250-","A63251-","T63252-","A63254-","T63255-","T63256-","A63259-","T63260-","A63262-","T63263-","A63265-","A63266-","A63268-","T63270-","A63272-","T63273-","T63274-","T63275-","A63277-","A63279-","A63280-","A63282-","T63283-","T63286-","A63291-","T63293-","A63294-","T63295-","T63296-","A63297-","A63298-","T63299-","T63303-","T63304-","T63305-","A63306-","T63308-","A63309-","A63310-","A63311-","A63313-","T63315-","A63318-","T63319-","T63322-","T63323-","A63326-","A63327-","T63328-","A63329-","A63330-","T63331-","A63332-","A63333-","A63334-","A63335-","T63337-","T63338-","T63340-","A63343-","A63344-","T63346-","T63347-","A63348-","A63349-","A63350-","A63353-","T63354-","A63355-","T63356-","T63357-","A63358-","T63359-","A63362-","T63363-","T63364-","T63367-","T63368-","T63369-","A63370-","A63371-","A63372-","A63374-","T63375-","A63376-","T63377-","A63379-","T63382-","A63384-","T63385-","T63387-","A63388-","A63389-","A63393-","A63395-","A63397-","A63398-","T63399-","T63400-","T63401-","T63402-","T63403-","T63404-","T63407-","A63408-","T63411-","T63412-","T63413-","T63414-","A63415-","A63417-","A63419-","T63421-","T63422-","T63423-","A63425-","A63426-","T63429-","A63430-","T63432-","T63433-","T63435-","T63436-","T63437-","A63438-","A63439-","A63441-","A63442-","A63443-","T63445-","T63446-","A63447-","T63448-","T63449-","A63451-","T63452-","T63455-","T63458-","T63460-","A63461-","T63463-","A63464-","T63465-","T63466-","T63468-","A63469-","T63470-","T63471-","T63472-","A63473-","A63474-","T63475-","T63476-","T63477-","T63478-","T63480-","A63481-","T63483-","T63484-","A63485-","A63486-","T63487-","T63488-","T63489-","A63490-","T63491-","A63493-","A63495-","T63496-","A63497-","T63498-","A63500-","A63502-","T63503-","T63504-","C89166T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"]}},"children":[{"name":"OQ672570","node_attrs":{"div":2,"accession":"OQ672570","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"02112022_anal"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672570/2022-11-02"},"date":{"value":"2022-11-02"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G49680-","G49710-","G62109-","G62115-","G62117-","C62119-","C62120-","G62130-","C62136-","G62137-","C62141-","G62142-","G62143-","C62146-","G62147-","C62166-","G62170-","G62172-","C62180-","G62185-","G62186-","C62193-","C62195-","C62196-","G62199-","C62201-","C62205-","G62208-","G62209-","C62210-","G62211-","G62212-","G62214-","C62215-","C62216-","G62218-","C62225-","C62226-","C62229-","G62234-","C62235-","C62243-","G62245-","G62250-","C62251-","G62253-","C62256-","G62257-","C62258-","G62260-","G62264-","C62267-","G62268-","G62269-","G62275-","C62276-","C62279-","C62280-","C62282-","C62283-","C62292-","G62302-","C62305-","G62309-","G62315-","G62317-","C62319-","C62322-","G62323-","C62325-","C62326-","G62329-","G62332-","C62337-","G62339-","G62341-","G62346-","C62348-","G62349-","C62353-","G62357-","C62361-","C62365-","C62376-","G62383-","C62387-","C62388-","G62389-","C62391-","G62398-","G62401-","G62402-","C62405-","G62407-","G62408-","C62413-","G62416-","C62418-","G62421-","C62428-","G62434-","G62439-","C62443-","C62444-","C62445-","C62448-","C62449-","G62457-","C62460-","C62462-","G62466-","G62473-","C62476-","C62477-","G62479-","G62485-","G62488-","G62502-","C62507-","G62512-","C62513-","C62519-","C62526-","G62527-","G62529-","G62530-","G62534-","C62536-","G62537-","C62538-","G62552-","G62554-","G62556-","G62559-","C62564-","C62565-","C62567-","C62569-","C62570-","G62571-","C62572-","C62575-","G62578-","C62583-","G62584-","C62585-","C62594-","C62595-","C62597-","G62602-","G62605-","G62606-","C62612-","C62613-","G62618-","G62620-","C62624-","C62628-","C62708-","C62714-","C62716-","G62721-","G62722-","G62725-","G62731-","G62737-","G62740-","G62741-","G62751-","C62753-","G62754-","C62755-","G62758-","G62760-","G62761-","G62766-","G62769-","C62773-","G62778-","G62779-","G62782-","G62785-","C62788-","C62791-","C62792-","C62798-","C62801-","C62802-","G62803-","C62808-","G62811-","C62819-","C62820-","C62825-","C62826-","C62829-","G62830-","G62831-","C62843-","G62844-","G62847-","C62853-","G62854-","G62855-","G62858-","C62860-","C62864-","C62868-","G62869-","G62870-","C62872-","G62880-","C62881-","C62887-","C62888-","C62890-","C62895-","G62896-","G62898-","C62900-","C62909-","C62911-","C62912-","C62919-","C62927-","G62930-","C62939-","G62941-","C62945-","G62946-","G62950-","G62951-","G62952-","C62958-","G62959-","C62967-","G62968-","G62974-","G62975-","G62980-","C62984-","C62985-","G62986-","G62987-","C62990-","G62994-","C62997-","G62998-","C63007-","C63014-","C63020-","G63022-","G63024-","G63025-","G63029-","C63032-","C63033-","G63034-","G63038-","G63039-","G63045-","C63047-","G63051-","G63055-","G63056-","C63068-","C63074-","G63077-","G63079-","C63081-","G63084-","G63088-","G63097-","C63099-","G63100-","G63105-","C63120-","C63122-","C63123-","C63125-","G63126-","G63128-","G63130-","C63134-","G63136-","G63137-","C63140-","C63143-","G63144-","C63146-","G63147-","C63149-","G63150-","C63151-","C63152-","G63154-","C63159-","C63160-","C63163-","C63164-","G63165-","G63169-","G63170-","G63172-","C63185-","G63196-","C63197-","C63199-","G63202-","G63209-","C63223-","C63224-","G63228-","C63234-","C63237-","C63240-","C63242-","G63243-","C63246-","G63247-","C63248-","G63249-","G63253-","C63257-","C63258-","G63261-","C63264-","G63267-","G63269-","G63271-","G63276-","G63278-","C63281-","C63284-","C63285-","C63287-","C63288-","G63289-","G63290-","G63292-","G63300-","G63301-","G63302-","G63307-","C63312-","G63314-","C63316-","C63317-","C63320-","G63321-","G63324-","C63325-","G63336-","G63339-","C63341-","C63342-","G63345-","G63351-","G63352-","G63360-","C63361-","C63365-","G63366-","G63373-","C63378-","C63380-","C63381-","C63383-","C63386-","C63390-","G63391-","G63392-","G63394-","C63396-","G63405-","G63406-","G63409-","G63410-","G63416-","G63418-","C63420-","G63424-","G63427-","C63428-","C63431-","G63434-","C63440-","G63444-","C63450-","C63453-","G63454-","C63456-","G63457-","C63459-","C63462-","C63467-","G63479-","G63482-","C63492-","C63494-","C63499-","C63501-","-180517A","-180518A","-180519T","-180520G","-180521A","-180522C","-180523G","-180524A","-180525T","-180526A","-180527T","-180528A","-180529C","-180530G","-180531G","-180532A","-180533T","-180534T"],"OPG068":["D494-"],"OPG081":["N46-","R47-","T48-","V49-","T50-","I51-","F52-","K53-","Y54-","I55-","G56-","L57-","F58-","I59-"]},"labels":{"aa":"OPG068: D494-; OPG081: N46-, R47-, T48-, V49-, T50-, I51-, F52-, K53-, Y54-, I55-, G56-, L57-, F58-, I59-"}}},{"name":"NODE_0000130","node_attrs":{"div":6,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C2621-","A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","C8201T","-62110A","-62111T","-62112A","-62113A","-62114A","-62116A","-62118T","-62121T","-62122A","-62123T","-62124A","-62125T","-62126A","-62127T","-62128T","-62129T","-62131A","-62132A","-62133A","-62134A","-62135T","-62138T","-62139T","-62140A","-62144T","-62145T","-62148A","-62149T","-62150T","-62151A","-62167A","-62168T","-62169T","-62171T","-62173A","-62174A","-62175T","-62176A","-62177T","-62178A","-62179T","-62181A","-62182T","-62183T","-62184A","-62187A","-62188T","-62189T","-62190T","-62191A","-62192A","-62194T","-62197T","-62198T","-62200A","-62202T","-62203A","-62204T","-62206A","-62207T","-62213T","-62217A","-62219A","-62220A","-62221A","-62222T","-62223T","-62224A","-62227A","-62228T","-62230A","-62231A","-62232A","-62233A","-62236A","-62237T","-62238T","-62239A","-62240A","-62241T","-62242A","-62244A","-62246T","-62247T","-62248A","-62249T","-62252A","-62254A","-62255T","-62259A","-62261T","-62262T","-62263A","-62265A","-62266A","-62270T","-62271T","-62272A","-62273T","-62274A","-62277A","-62278T","-62281A","-62284A","-62285T","-62286T","-62287T","-62288A","-62289T","-62290A","-62291T","-62293T","-62294A","-62295A","-62296A","-62297A","-62298A","-62299T","-62300T","-62301A","-62303A","-62304T","-62306A","-62307A","-62308A","-62310A","-62311A","-62312T","-62313A","-62314T","-62316T","-62318A","-62320A","-62321A","-62324T","-62327T","-62328A","-62330T","-62331T","-62333T","-62334A","-62335T","-62336A","-62338T","-62340A","-62342A","-62343A","-62344T","-62345T","-62347A","-62350A","-62351A","-62352A","-62354A","-62355A","-62356T","-62358T","-62359T","-62360T","-62362T","-62363T","-62364A","-62366A","-62367T","-62368A","-62369T","-62370T","-62371T","-62372T","-62373T","-62374T","-62375T","-62377T","-62378T","-62379A","-62380T","-62381T","-62382A","-62384T","-62385A","-62386A","-62390A","-62392T","-62393T","-62394A","-62395A","-62396T","-62397A","-62399T","-62400A","-62403A","-62404A","-62406T","-62409A","-62410A","-62411A","-62412A","-62414T","-62415A","-62417A","-62419T","-62420T","-62422A","-62423T","-62424T","-62425A","-62426T","-62427T","-62429T","-62430A","-62431T","-62432A","-62433A","-62435T","-62436A","-62437T","-62438A","-62440A","-62441T","-62442A","-62446T","-62447T","-62450A","-62451A","-62452A","-62453T","-62454A","-62455A","-62456T","-62458T","-62459T","-62461T","-62463T","-62464T","-62465T","-62467A","-62468T","-62469A","-62470A","-62471A","-62472A","-62474T","-62475T","-62478A","-62480A","-62481A","-62482A","-62483A","-62484T","-62486T","-62487A","-62489A","-62490A","-62491T","-62492T","-62493T","-62494T","-62495T","-62496T","-62497A","-62498A","-62499A","-62500A","-62501A","-62503T","-62504T","-62505A","-62506T","-62508T","-62509T","-62510T","-62511T","-62514T","-62515A","-62516T","-62517T","-62518A","-62520T","-62521A","-62522A","-62523T","-62524A","-62525T","-62528T","-62531T","-62532T","-62533A","-62535A","-62539T","-62540T","-62541A","-62542T","-62543T","-62544A","-62545T","-62546T","-62547A","-62548A","-62549T","-62550A","-62551T","-62553A","-62555T","-62557A","-62558T","-62560A","-62561A","-62562A","-62563T","-62566A","-62568A","-62573T","-62574T","-62576T","-62577A","-62579A","-62580T","-62581A","-62582T","-62586T","-62587T","-62588T","-62589T","-62590A","-62591T","-62592T","-62593T","-62596A","-62598A","-62599T","-62600T","-62601A","-62603A","-62604T","-62607T","-62608A","-62609A","-62610A","-62611T","-62614A","-62615A","-62616T","-62617A","-62619T","-62621A","-62622A","-62623A","-62625T","-62626A","-62627T","-62629T","-62630T","-62703A","-62704T","-62705A","-62706A","-62707A","-62709A","-62710A","-62711T","-62712T","-62713T","-62715A","-62717A","-62718A","-62719A","-62720T","-62723A","-62724T","-62726T","-62727T","-62728A","-62729A","-62730T","-62732T","-62733A","-62734T","-62735T","-62736A","-62738T","-62739A","-62742A","-62743A","-62744A","-62745T","-62746T","-62747T","-62748T","-62749T","-62750T","-62752A","-62756T","-62757A","-62759T","-62762A","-62763A","-62764T","-62765T","-62767A","-62768A","-62770A","-62771T","-62772T","-62774T","-62775A","-62776A","-62777T","-62780A","-62781T","-62783A","-62784T","-62786T","-62787T","-62789T","-62790A","-62793T","-62794A","-62795T","-62796T","-62797T","-62799A","-62800T","-62804A","-62805T","-62806A","-62807A","-62809A","-62810T","-62812T","-62813T","-62814A","-62815A","-62816T","-62817T","-62818T","-62821A","-62822A","-62823T","-62824A","-62827A","-62828A","-62832T","-62833T","-62834T","-62835T","-62836A","-62837A","-62838T","-62839A","-62840T","-62841T","-62842T","-62845A","-62846T","-62848A","-62849T","-62850A","-62851T","-62852A","-62856T","-62857A","-62859T","-62863T","-62865T","-62866T","-62867T","-62871A","-62873T","-62874T","-62875A","-62876T","-62877A","-62878T","-62879A","-62882T","-62883T","-62884A","-62885T","-62886T","-62889A","-62891A","-62892A","-62893T","-62894A","-62897A","-62899T","-62901A","-62902T","-62903T","-62904A","-62905T","-62906A","-62907T","-62908A","-62910T","-62913A","-62914A","-62915A","-62916A","-62917A","-62918A","-62920A","-62921A","-62922A","-62923A","-62924T","-62925A","-62926A","-62928T","-62929A","-62931T","-62932A","-62933T","-62934A","-62935A","-62936A","-62937A","-62938T","-62940T","-62942T","-62943A","-62944T","-62947A","-62948A","-62949T","-62953A","-62954A","-62955A","-62956A","-62957A","-62960A","-62961A","-62962A","-62963T","-62964T","-62965A","-62966T","-62969A","-62970T","-62971A","-62972T","-62973A","-62976T","-62977A","-62978T","-62979A","-62981A","-62982A","-62983T","-62988A","-62989A","-62991A","-62992T","-62993T","-62995A","-62996A","-62999T","-63000A","-63001T","-63002T","-63003A","-63004A","-63005T","-63006A","-63008T","-63009T","-63010A","-63011A","-63012T","-63013T","-63015T","-63016T","-63017T","-63018T","-63019T","-63021A","-63023T","-63026T","-63027A","-63028A","-63030A","-63031A","-63035A","-63036T","-63037A","-63040T","-63041T","-63042A","-63043T","-63044T","-63046A","-63048A","-63049T","-63050T","-63052T","-63053A","-63054T","-63057T","-63058T","-63059T","-63060T","-63061A","-63062A","-63063A","-63064T","-63065A","-63066T","-63067T","-63069T","-63070A","-63071T","-63072A","-63073A","-63075T","-63076T","-63078A","-63080A","-63082T","-63083T","-63085A","-63086T","-63087A","-63089A","-63090T","-63091A","-63092T","-63093T","-63094A","-63095A","-63096T","-63098A","-63101A","-63102A","-63103T","-63104T","-63106A","-63107A","-63108A","-63109A","-63110T","-63111T","-63112A","-63113T","-63114T","-63115T","-63116T","-63117T","-63118A","-63119T","-63121A","-63124A","-63127T","-63129T","-63131T","-63132T","-63133T","-63135A","-63138A","-63139T","-63141A","-63142T","-63145T","-63148A","-63153A","-63155T","-63156T","-63157A","-63158A","-63161A","-63162A","-63166A","-63167A","-63168T","-63171A","-63173T","-63174A","-63175A","-63176A","-63177A","-63178T","-63179A","-63180A","-63181A","-63182T","-63183A","-63184T","-63186A","-63187T","-63188T","-63189A","-63190A","-63191T","-63192A","-63193T","-63194A","-63195T","-63198T","-63200T","-63201A","-63203A","-63204T","-63205A","-63206T","-63207T","-63208A","-63210T","-63211A","-63212T","-63213T","-63214T","-63215T","-63216T","-63217A","-63218T","-63219T","-63220A","-63221A","-63222T","-63225T","-63226T","-63227T","-63229A","-63230T","-63231T","-63232A","-63233T","-63235A","-63236T","-63238T","-63239T","-63241T","-63244T","-63245A","-63250A","-63251A","-63252T","-63254A","-63255T","-63256T","-63259A","-63260T","-63262A","-63263T","-63265A","-63266A","-63268A","-63270T","-63272A","-63273T","-63274T","-63275T","-63277A","-63279A","-63280A","-63282A","-63283T","-63286T","-63291A","-63293T","-63294A","-63295T","-63296T","-63297A","-63298A","-63299T","-63303T","-63304T","-63305T","-63306A","-63308T","-63309A","-63310A","-63311A","-63313A","-63315T","-63318A","-63319T","-63322T","-63323T","-63326A","-63327A","-63328T","-63329A","-63330A","-63331T","-63332A","-63333A","-63334A","-63335A","-63337T","-63338T","-63340T","-63343A","-63344A","-63346T","-63347T","-63348A","-63349A","-63350A","-63353A","-63354T","-63355A","-63356T","-63357T","-63358A","-63359T","-63362A","-63363T","-63364T","-63367T","-63368T","-63369T","-63370A","-63371A","-63372A","-63374A","-63375T","-63376A","-63377T","-63379A","-63382T","-63384A","-63385T","-63387T","-63388A","-63389A","-63393A","-63395A","-63397A","-63398A","-63399T","-63400T","-63401T","-63402T","-63403T","-63404T","-63407T","-63408A","-63411T","-63412T","-63413T","-63414T","-63415A","-63417A","-63419A","-63421T","-63422T","-63423T","-63425A","-63426A","-63429T","-63430A","-63432T","-63433T","-63435T","-63436T","-63437T","-63438A","-63439A","-63441A","-63442A","-63443A","-63445T","-63446T","-63447A","-63448T","-63449T","-63451A","-63452T","-63455T","-63458T","-63460T","-63461A","-63463T","-63464A","-63465T","-63466T","-63468T","-63469A","-63470T","-63471T","-63472T","-63473A","-63474A","-63475T","-63476T","-63477T","-63478T","-63480T","-63481A","-63483T","-63484T","-63485A","-63486A","-63487T","-63488T","-63489T","-63490A","-63491T","-63493A","-63495A","-63496T","-63497A","-63498T","-63500A","-63502A","-63503T","-63504T","C151552T","C167451T","G187391A","A194549-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-"],"OPG002":["R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-","C47-"],"OPG002_dup":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-"],"OPG178":["S15F"]},"labels":{"aa":"OPG002: R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-, C47-; OPG002_dup: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-; OPG178: S15F"}},"children":[{"name":"OQ672572","node_attrs":{"div":6,"accession":"OQ672572","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"26012023_anal"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672572/2023-01-26"},"date":{"value":"2023-01-26"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-47746G","-62861T","-62862C"]}}},{"name":"OQ672574","node_attrs":{"div":6,"accession":"OQ672574","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"02022023_anal"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672574/2023-02-02"},"date":{"value":"2023-02-02"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-2623A","-2624C","-2625A","-2626T","-2627A","-2628G","-2629A","-2630T","-2631T","-2632A","-2633C","-2634G","-2635G","-2636C","-2637T","-2638T","-2639C","-2640T","-2641G","-2642T","-2643A","-2644T","-2645T","-2646C","-2647G","-2648T","-2649T","-2650G","-2651T","-2652C","-194549A","-194550A","-194551G","-194552T","-194553G","-194554T","-194555A","-194556A","-194557A","-194558G","-194559A","-194560C","-194561A","-194562A","-194563C","-194564G","-194565A","-194566A","-194567T","-194568A","-194569C","-194570A","-194571G","-194572A","-194573A","-194574G","-194575C","-194576C","-194577G","-194578T","-194579A","-194580A","-194581T","-194582C","-194583T","-194584A","-194585T"],"OPG002":["-38R","-39S","-40R","-41N","-42L","-43C","-45L","-46S","-47C"],"OPG002_dup":["-31K","-32C","-33K","-34D","-35N","-36E","-37Y","-38R","-39S","-40R","-41N","-42L","-43C"]},"labels":{"aa":"OPG002: -38R, -39S, -40R, -41N, -42L, -43C, -45L, -46S, -47C; OPG002_dup: -31K, -32C, -33K, -34D, -35N, -36E, -37Y, -38R, -39S, -40R, -41N, -42L, -43C"}}},{"name":"NODE_0000131","node_attrs":{"div":7,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A2611-","C2612-","A2613-","C2614-","G2615-","A2616-","T2617-","A2618-","G2619-","A2620-","A2622-","T2653-","T2654-","T2655-","A2656-","C2657-","A2658-","C2659-","T2660-","T2661-","T39397C","T47695-","C47696-","A47697-","T47698-","T47699-","A47700-","C47701-","G47702-","A47703-","G47704-","A47705-","C47706-","A47707-","T47708-","T47709-","G47710-","A47711-","A47712-","A47713-","C47714-","T47715-","A47716-","G47717-","G47718-","A47719-","T47720-","A47721-","T47722-","A47723-","T47724-","A47725-","A47726-","A47727-","A47728-","T47729-","T47730-","T47731-","A47732-","A47733-","G47734-","G47735-","G47736-","A47737-","A47738-","T47739-","G47740-","A47741-","T47742-","T47743-","A47744-","G47745-","A47747-","C47748-","T47749-","A47750-","C47751-","T47752-","A47753-","C47754-","T47755-","C47756-","T47757-","A47758-","G47759-","A47760-","A47761-","G47762-","A47763-","T47764-","A47765-","T47766-","A47767-","G47768-","C47769-","A47770-","C47771-","C47772-","A47773-","T47774-","C47775-","T47776-","A47777-","T47778-","T47779-","C47780-","C47781-","A47782-","A47783-","A47784-","T47785-","A47786-","A47787-","T47788-","C47789-","A47790-","G47791-","A47792-","A47793-","A47794-","A47795-","C47796-","T47797-","T47798-","A47799-","T47800-","A47801-","A47802-","A47803-","C47804-","T47805-","A47806-","T47807-","T47808-","C47809-","T47810-","C47811-","G47812-","G47813-","A47814-","C47815-","A47816-","T47817-","T47818-","T47819-","C47820-","A47821-","G47822-","T47823-","C47824-","A47825-","T47826-","T47827-","G47828-","G47829-","C47830-","A47831-","A47832-","A47833-","G47834-","C47835-","A47836-","T47837-","C47838-","A47839-","C47840-","A47841-","G47842-","A47843-","A47844-","T47845-","C47846-","C47847-","G47848-","A47849-","G47850-","T47851-","A47852-","A47853-","G47854-","A47855-","T47856-","G47857-","A47858-","T47859-","A47860-","T47861-","A47862-","T47863-","G47864-","C47865-","T47866-","C47867-","G47868-","C47869-","T47870-","G47871-","C47872-","T47873-","T47874-","T47875-","A47876-","C47877-","A47878-","T47879-","G47880-","T47881-","T47882-","T47883-","C47884-","C47885-","C47886-","A47887-","A47888-","T47889-","T47890-","T47891-","G47892-","T47893-","T47894-","T47895-","G47896-","G47897-","A47898-","G47899-","A47900-","T47901-","G47902-","A47903-","C47904-","C47905-","A47906-","T47907-","A47908-","G47909-","A47910-","T47911-","T47912-","C47913-","A47914-","T47915-","T47916-","T47917-","G47918-","T47919-","T47920-","A47921-","T47922-","A47923-","G47924-","A47925-","A47926-","T47927-","G47928-","C47929-","A47930-","T47931-","C47932-","C47933-","A47934-","A47935-","C47936-","A47937-","T47938-","T47939-","G47940-","T47941-","T47942-","C47943-","A47944-","T47945-","G47946-","A47947-","T47948-","A47949-","T47950-","A47951-","G47952-","T47953-","T47954-","G47955-","A47956-","A47957-","T47958-","C47959-","A47960-","T47961-","G47962-","T47963-","A47964-","T47965-","G47966-","C47967-","C47968-","T47969-","G47970-","T47971-","T47972-","C47973-","G47974-","T47975-","A47976-","T47977-","G47978-","C47979-","C47980-","T47981-","G47982-","T47983-","G47984-","G47985-","C47986-","T47987-","A47988-","A47989-","G47990-","A47991-","T47992-","A47993-","C47994-","T47995-","G47996-","T47997-","G47998-","T47999-","A48000-","A48001-","A48002-","G48003-","A48004-","A48005-","A48006-","T48007-","G48008-","G48009-","T48010-","A48011-","A48012-","A48013-","T48014-","A48015-","A48016-","A48017-","T48018-","A48019-","C48020-","T48021-","T48022-","T48023-","G48024-","A48025-","G48026-","A48027-","A48028-","T48029-","C48030-","T48031-","T48032-","T48033-","A48034-","A48035-","G48036-","A48037-","G48038-","T48039-","G48040-","C48041-","A48042-","T48043-","T48044-","G48045-","A48046-","C48047-","T48048-","T48049-","T48050-","G48051-","T48052-","T48053-","A48054-","G48055-","T48056-","G48057-","A48058-","A48059-","T48060-","A48061-","G48062-","G48063-","C48064-","A48065-","T48066-","T48067-","C48068-","C48069-","A48070-","T48071-","C48072-","T48073-","T48074-","T48075-","C48076-","T48077-","C48078-","C48079-","A48080-","A48081-","T48082-","A48083-","C48084-","T48085-","A48086-","A48087-","T48088-","T48089-","C48090-","A48091-","A48092-","A48093-","T48094-","T48095-","G48096-","T48097-","T48098-","A48099-","A48100-","A48101-","T48102-","T48103-","A48104-","A48105-","T48106-","A48107-","A48108-","T48109-","G48110-","G48111-","A48112-","A48113-","T48114-","A48115-","G48116-","T48117-","A48118-","T48119-","A48120-","A48121-","A48122-","T48123-","A48124-","G48125-","T48126-","T48127-","A48128-","T48129-","T48130-","A48131-","G48132-","T48133-","G48134-","A48135-","T48136-","A48137-","G48138-","G48139-","A48140-","T48141-","A48142-","G48143-","T48144-","A48145-","A48146-","A48147-","C48148-","A48149-","T48150-","A48151-","A48152-","T48153-","T48154-","A48155-","T48156-","T48157-","A48158-","G48159-","A48160-","A48161-","T48162-","A48163-","G48164-","T48165-","A48166-","G48167-","T48168-","G48169-","T48170-","A48171-","G48172-","T48173-","A48174-","T48175-","C48176-","A48177-","T48178-","A48179-","G48180-","A48181-","T48182-","A48183-","A48184-","C48185-","T48186-","C48187-","T48188-","C48189-","T48190-","T48191-","C48192-","T48193-","A48194-","T48195-","A48196-","A48197-","A48198-","A48199-","A48200-","A48201-","T48202-","G48203-","G48204-","A48205-","T48206-","T48207-","T48208-","T48209-","A48210-","T48211-","T48212-","C48213-","G48214-","T48215-","A48216-","G48217-","A48218-","A48219-","A48220-","G48221-","T48222-","A48223-","T48224-","C48225-","T48226-","T48227-","A48228-","T48229-","A48230-","T48231-","A48232-","C48233-","A48234-","C48235-","A48236-","G48237-","T48238-","A48239-","G48240-","A48241-","A48242-","A48243-","A48244-","T48245-","A48246-","A48247-","T48248-","A48249-","T48250-","A48251-","G48252-","A48253-","T48254-","T48255-","T48256-","T48257-","T48258-","T48259-","A48260-","A48261-","A48262-","G48263-","G48264-","A48265-","T48266-","G48267-","A48268-","T48269-","A48270-","C48271-","A48272-","T48273-","T48274-","A48275-","A48276-","G48277-","T48278-","A48279-","A48280-","A48281-","G48282-","T48283-","A48284-","A48285-","A48286-","C48287-","A48288-","A48289-","T48290-","T48291-","T48292-","T48293-","A48294-","C48295-","C48296-","C48297-","T48298-","C48299-","A48300-","A48301-","T48302-","C48303-","A48304-","T48305-","G48306-","T48307-","A48308-","C48309-","T48310-","A48311-","G48312-","C48313-","T48314-","C48315-","T48316-","C48317-","A48318-","A48319-","G48320-","T48321-","A48322-","T48323-","C48324-","T48325-","A48326-","G48327-","T48328-","T48329-","A48330-","G48331-","C48332-","A48333-","A48334-","T48335-","T48336-","T48337-","T48338-","C48339-","C48340-","T48341-","C48342-","A48343-","A48344-","C48345-","A48346-","T48347-","G48348-","T48349-","T48350-","A48351-","T48352-","T48353-","A48354-","C48355-","T48356-","A48357-","A48358-","G48359-","G48360-","A48361-","T48362-","G48363-","T48364-","A48365-","T48366-","T48367-","A48368-","G48369-","C48370-","T48371-","A48372-","A48373-","T48374-","A48375-","C48376-","C48377-","A48378-","A48379-","T48380-","T48381-","T48382-","T48383-","T48384-","T48385-","T48386-","G48387-","T48388-","T48389-","T48390-","T48391-","C48392-","A48393-","T48394-","A48395-","C48396-","A48397-","T48398-","A48399-","T48400-","G48401-","G48402-","T48403-","A48404-","C48405-","G48406-","A48407-","T48408-","G48409-","C48410-","T48411-","G48412-","T48413-","A48414-","A48415-","A48416-","G48417-","T48418-","A48419-","T48420-","A48421-","C48422-","G48423-","A48424-","A48425-","G48426-","C48427-","G48428-","G48429-","T48430-","T48431-","T48432-","T48433-","A48434-","C48435-","G48436-","A48437-","C48438-","A48439-","C48440-","G48441-","C48442-","A48443-","T48444-","T48445-","T48446-","G48447-","A48448-","T48449-","G48450-","C48451-","A48452-","C48453-","C48454-","C48455-","A48456-","C48457-","G48458-","T48459-","T48460-","G48461-","T48462-","A48463-","C48464-","G48465-","T48466-","T48467-","A48468-","A48469-","A48470-","G48471-","C48472-","A48473-","T48474-","T48475-","G48476-","A48477-","C48478-","T48479-","A48480-","A48481-","G48482-","A48483-","A48484-","T48485-","T48486-","A48487-","T48488-","T48489-","T48490-","A48491-","T48492-","C48493-","G48494-","T48495-","T48496-","T48497-","A48498-","G48499-","T48500-","A48501-","A48502-","C48503-","A48504-","C48505-","A48506-","A48507-","T48508-","A48509-","C48510-","A48511-","G48512-","T48513-","C48514-","G48515-","T48516-","A48517-","C48518-","A48519-","A48520-","G48521-","G48522-","A48523-","A48524-","A48525-","C48526-","A48527-","G48528-","T48529-","G48530-","C48531-","A48532-","T48533-","A48534-","A48535-","A48536-","C48537-","T48538-","A48539-","A48540-","C48541-","A48542-","C48543-","A48544-","A48545-","G48546-","A48547-","T48548-","G48549-","A48550-","A48551-","A48552-","A48553-","A48554-","T48555-","T48556-","T48557-","T48558-","T48559-","A48560-","G48561-","A48562-","G48563-","G48564-","T48565-","T48566-","G48567-","C48568-","C48569-","G48570-","A48571-","A48572-","T48573-","A48574-","C48575-","A48576-","T48577-","G48578-","G48579-","A48580-","C48581-","G48582-","A48583-","A48584-","T48585-","T48586-","A48587-","G48588-","G48589-","A48590-","G48591-","A48592-","A48593-","C48594-","T48595-","T48596-","A48597-","T48598-","A48599-","G48600-","G48601-","C48602-","G48603-","T48604-","A48605-","A48606-","A48607-","T48608-","T48609-","A48610-","T48611-","G48612-","A48613-","C48614-","T48615-","T48616-","A48617-","G48618-","T48619-","T48620-","C48621-","T48622-","T48623-","A48624-","A48625-","T48626-","C48627-","C48628-","A48629-","T48630-","T48631-","A48632-","T48633-","T48634-","T48635-","C48636-","A48637-","C48638-","G48639-","G48640-","A48641-","G48642-","G48643-","G48644-","G48645-","A48646-","A48647-","C48648-","C48649-","C48650-","A48651-","T48652-","C48653-","A48654-","A48655-","A48656-","G48657-","A48658-","T48659-","A48660-","T48661-","G48662-","G48663-","A48664-","A48665-","A48666-","T48667-","C48668-","A48669-","T48670-","T48671-","T48672-","T48673-","T48674-","T48675-","T48676-","A48677-","A48678-","A48679-","A48680-","C48681-","T48682-","G48683-","T48684-","T48685-","T48686-","A48687-","A48688-","G48689-","A48690-","A48691-","A48692-","A48693-","C48694-","A48695-","G48696-","A48697-","C48698-","T48699-","T48700-","C48701-","A48702-","A48703-","A48704-","G48705-","T48706-","T48707-","G48708-","T48709-","T48710-","A48711-","A48712-","A48713-","A48714-","A48715-","A48716-","T48717-","T48718-","A48719-","A48720-","G48721-","T48722-","G48723-","T48724-","T48725-","A48726-","T48727-","A48728-","A48729-","G48730-","A48731-","T48732-","T48733-","A48734-","C48735-","T48736-","T48737-","A48738-","T48739-","T48740-","T48741-","G48742-","G48743-","G48744-","C48745-","A48746-","T48747-","A48748-","C48749-","C48750-","T48751-","A48752-","A48753-","G48754-","C48755-","A48756-","A48757-","G48758-","A48759-","A48760-","A48761-","G48762-","A48763-","T48764-","A48765-","C48766-","A48767-","G48768-","G48769-","C48770-","A48771-","T48772-","A48773-","G48774-","A48775-","G48776-","T48777-","T48778-","T48779-","G48780-","C48781-","G48782-","G48783-","A48784-","T48785-","A48786-","A48787-","T48788-","G48789-","A48790-","T48791-","A48792-","G48793-","A48794-","C48795-","A48796-","A48797-","G48798-","A48799-","T48800-","A48801-","T48802-","A48803-","T48804-","A48805-","T48806-","A48807-","C48808-","T48809-","C48810-","T48811-","A48812-","T48813-","T48814-","T48815-","C48816-","A48817-","A48818-","C48819-","A48820-","A48821-","A48822-","C48823-","T48824-","G48825-","G48826-","T48827-","A48828-","G48829-","A48830-","A48831-","T48832-","A48833-","G48834-","T48835-","C48836-","C48837-","A48838-","T48839-","A48840-","G48841-","C48842-","A48843-","A48844-","T48845-","C48846-","T48847-","A48848-","A48849-","C48850-","A48851-","G48852-","A48853-","A48854-","A48855-","C48856-","G48857-","T48858-","T48859-","T48860-","A48861-","G48862-","G48863-","G48864-","A48865-","T48866-","T48867-","A48868-","T48869-","A48870-","T48871-","C48872-","T48873-","T48874-","T48875-","C48876-","C48877-","C48878-","G48879-","G48880-","A48881-","G48882-","A48883-","T48884-","A48885-","A48886-","G48887-","A48888-","C48889-","T48890-","A48891-","G48892-","C48893-","T48894-","A48895-","T48896-","T48897-","G48898-","G48899-","G48900-","T48901-","G48902-","T48903-","G48904-","G48905-","T48906-","T48907-","A48908-","A48909-","A48910-","C48911-","G48912-","A48913-","A48914-","A48915-","G48916-","T48917-","A48918-","T48919-","A48920-","G48921-","C48922-","T48923-","A48924-","A48925-","T48926-","G48927-","A48928-","T48929-","G48930-","C48931-","G48932-","G48933-","A48934-","T48935-","A48936-","T48937-","C48938-","G48939-","T48940-","T48941-","A48942-","T48943-","T48944-","A48945-","A48946-","T48947-","A48948-","G48949-","A48950-","C48951-","C48952-","C48953-","G48954-","C48955-","C48956-","A48957-","T48958-","T48959-","A48960-","C48961-","C48962-","A48963-","T48964-","G48965-","T48966-","A48967-","T48968-","G48969-","A48970-","T48971-","A48972-","A48973-","A48974-","A48975-","T48976-","T48977-","C48978-","T48979-","T48980-","A48981-","G48982-","T48983-","T48984-","A48985-","T48986-","A48987-","T48988-","A48989-","T48990-","A48991-","C48992-","T48993-","C48994-","T48995-","G48996-","A48997-","G48998-","A48999-","T49000-","A49001-","A49002-","A49003-","A49004-","C49005-","A49006-","G49007-","G49008-","G49009-","A49010-","C49011-","G49012-","C49013-","G49014-","T49015-","T49016-","A49017-","A49018-","T49019-","A49020-","A49021-","A49022-","A49023-","A49024-","C49025-","A49026-","T49027-","G49028-","C49029-","T49030-","T49031-","A49032-","A49033-","G49034-","T49035-","T49036-","A49037-","G49038-","T49039-","T49040-","T49041-","A49042-","T49043-","A49044-","T49045-","C49046-","T49047-","T49048-","T49049-","G49050-","A49051-","G49052-","C49053-","C49054-","T49055-","G49056-","A49057-","A49058-","A49059-","A49060-","A49061-","G49062-","A49063-","T49064-","A49065-","T49066-","C49067-","A49068-","G49069-","A49070-","G49071-","A49072-","A49073-","C49074-","T49075-","T49076-","C49077-","T49078-","G49079-","C49080-","T49081-","A49082-","G49083-","A49084-","A49085-","A49086-","T49087-","C49088-","A49089-","T49090-","A49091-","T49092-","A49093-","T49094-","G49095-","A49096-","T49097-","A49098-","T49099-","T49100-","C49101-","C49102-","T49103-","G49104-","G49105-","A49106-","G49107-","A49108-","T49109-","A49110-","T49111-","C49112-","C49113-","T49114-","A49115-","T49116-","C49117-","T49118-","A49119-","T49120-","T49121-","A49122-","T49123-","T49124-","G49125-","A49126-","T49127-","G49128-","C49129-","A49130-","A49131-","A49132-","A49133-","A49134-","A49135-","C49136-","G49137-","A49138-","C49139-","G49140-","A49141-","T49142-","T49143-","G49144-","G49145-","A49146-","A49147-","A49148-","A49149-","A49150-","A49151-","T49152-","A49153-","T49154-","T49155-","T49156-","T49157-","A49158-","T49159-","T49160-","A49161-","G49162-","T49163-","T49164-","T49165-","T49166-","T49167-","A49168-","C49169-","A49170-","A49171-","A49172-","G49173-","C49174-","T49175-","A49176-","A49177-","T49178-","T49179-","T49180-","T49181-","A49182-","T49183-","T49184-","A49185-","A49186-","C49187-","G49188-","G49189-","T49190-","A49191-","A49192-","T49193-","A49194-","C49195-","A49196-","T49197-","T49198-","T49199-","A49200-","T49201-","T49202-","A49203-","G49204-","T49205-","G49206-","A49207-","T49208-","A49209-","G49210-","A49211-","A49212-","C49213-","G49214-","T49215-","T49216-","T49217-","A49218-","A49219-","C49220-","G49221-","A49222-","T49223-","G49224-","A49225-","C49226-","T49227-","T49228-","A49229-","T49230-","T49231-","C49232-","A49233-","G49234-","A49235-","G49236-","T49237-","T49238-","G49239-","T49240-","T49241-","G49242-","T49243-","T49244-","C49245-","A49246-","A49247-","A49248-","T49249-","A49250-","G49251-","A49252-","T49253-","C49254-","C49255-","C49256-","G49257-","A49258-","A49259-","T49260-","A49261-","T49262-","T49263-","T49264-","C49265-","G49266-","A49267-","T49268-","A49269-","A49270-","T49271-","G49272-","A49273-","A49274-","C49275-","G49276-","A49277-","A49278-","T49279-","T49280-","A49281-","T49282-","G49283-","T49284-","C49285-","T49286-","T49287-","T49288-","A49289-","T49290-","T49291-","C49292-","T49293-","A49294-","T49295-","A49296-","C49297-","G49298-","A49299-","G49300-","T49301-","G49302-","C49303-","T49304-","G49305-","C49306-","G49307-","G49308-","A49309-","C49310-","A49311-","T49312-","T49313-","A49314-","A49315-","A49316-","C49317-","G49318-","A49319-","T49320-","T49321-","T49322-","G49323-","A49324-","T49325-","G49326-","A49327-","G49328-","T49329-","T49330-","A49331-","G49332-","A49333-","T49334-","A49335-","T49336-","T49337-","A49338-","A49339-","T49340-","A49341-","A49342-","C49343-","A49344-","G49345-","T49346-","T49347-","A49348-","T49349-","A49350-","T49351-","A49352-","T49353-","C49354-","T49355-","A49356-","A49357-","T49358-","A49359-","T49360-","A49361-","A49362-","T49363-","T49364-","T49365-","A49366-","T49367-","G49368-","A49369-","G49370-","G49371-","T49372-","G49373-","A49374-","A49375-","C49376-","G49377-","A49378-","T49379-","A49380-","T49381-","C49382-","A49383-","C49384-","A49385-","T49386-","T49387-","A49388-","G49389-","A49390-","T49391-","A49392-","C49393-","A49394-","A49395-","T49396-","G49397-","G49398-","A49399-","T49400-","G49401-","A49402-","T49403-","A49404-","T49405-","G49406-","A49407-","A49408-","G49409-","A49410-","A49411-","G49412-","T49413-","G49414-","T49415-","C49416-","A49417-","A49418-","A49419-","T49420-","C49421-","T49422-","T49423-","T49424-","A49425-","A49426-","C49427-","G49428-","A49429-","G49430-","G49431-","A49432-","T49433-","A49434-","C49435-","G49436-","T49437-","T49438-","G49439-","T49440-","A49441-","T49442-","T49443-","A49444-","T49445-","G49446-","T49447-","T49448-","A49449-","A49450-","G49451-","G49452-","A49453-","A49454-","T49455-","A49456-","C49457-","A49458-","A49459-","T49460-","A49461-","C49462-","A49463-","T49464-","A49465-","C49466-","C49467-","T49468-","G49469-","T49470-","T49471-","T49472-","T49473-","T49474-","G49475-","C49476-","A49477-","C49478-","G49479-","A49480-","G49481-","T49482-","C49483-","G49484-","G49485-","A49486-","T49487-","C49488-","C49489-","C49490-","A49491-","T49492-","G49493-","G49494-","T49495-","C49496-","A49497-","T49498-","A49499-","G49500-","A49501-","G49502-","A49503-","A49504-","C49505-","G49506-","G49507-","A49508-","A49509-","T49510-","A49511-","C49512-","T49513-","A49514-","A49515-","A49516-","G49517-","A49518-","A49519-","A49520-","C49521-","T49522-","G49523-","T49524-","C49525-","A49526-","T49527-","C49528-","T49529-","A49530-","T49531-","A49532-","A49533-","A49534-","A49535-","T49536-","C49537-","C49538-","A49539-","A49540-","G49541-","A49542-","G49543-","T49544-","A49545-","G49546-","A49547-","C49548-","G49549-","G49550-","C49551-","T49552-","G49553-","A49554-","A49555-","C49556-","T49557-","T49558-","G49559-","T49560-","T49561-","T49562-","A49563-","G49564-","C49565-","A49566-","A49567-","A49568-","A49569-","A49570-","C49571-","A49572-","T49573-","T49574-","T49575-","T49576-","A49577-","A49578-","A49579-","A49580-","T49581-","A49582-","T49583-","T49584-","A49585-","T49586-","T49587-","T49588-","A49589-","G49590-","A49591-","C49592-","G49593-","G49594-","A49595-","C49596-","A49597-","A49598-","T49599-","T49600-","G49601-","G49602-","C49603-","T49604-","C49605-","G49606-","T49607-","C49608-","T49609-","A49610-","G49611-","G49612-","T49613-","C49614-","T49615-","T49616-","G49617-","T49618-","G49619-","T49620-","T49621-","A49622-","G49623-","A49624-","T49625-","G49626-","A49627-","T49628-","T49629-","A49630-","T49631-","A49632-","A49633-","A49634-","G49635-","G49636-","A49637-","G49638-","A49639-","C49640-","T49641-","T49642-","A49643-","T49644-","T49645-","A49646-","G49647-","T49648-","T49649-","A49650-","A49651-","A49652-","A49653-","T49654-","G49655-","A49656-","T49657-","A49658-","A49659-","A49660-","C49661-","C49662-","A49663-","T49664-","C49665-","T49666-","C49667-","A49668-","A49669-","A49670-","T49671-","C49672-","T49673-","G49674-","T49675-","G49676-","G49677-","A49678-","G49679-","G49680-","A49681-","T49682-","G49683-","T49684-","A49685-","T49686-","C49687-","C49688-","G49689-","C49690-","A49691-","T49692-","T49693-","C49694-","G49695-","T49696-","T49697-","A49698-","G49699-","A49700-","T49701-","T49702-","T49703-","T49704-","C49705-","T49706-","A49707-","C49708-","A49709-","G49710-","A49711-","G61794-","G61795-","C61796-","A61797-","T61798-","A61815-","G61816-","T61817-","A61818-","C61819-","A61820-","A61821-","G61822-","T61823-","G61824-","G61825-","C61826-","T61827-","G61828-","C61829-","T61830-","A61831-","T61832-","T61833-","T61834-","C61835-","G61836-","G61837-","C61838-","T61839-","G61840-","C61841-","C61842-","A61843-","G61844-","A61845-","G61846-","T61847-","G61848-","T61849-","C61850-","C61851-","A61852-","A61853-","T61854-","T61855-","C61856-","T61857-","A61858-","C61859-","C61860-","G61861-","T61862-","T61863-","G61864-","T61865-","T61866-","A61867-","C61868-","T61869-","C61870-","C61871-","A61872-","T61873-","T61874-","A61875-","T61876-","A61877-","T61878-","A61879-","T61880-","T61881-","C61882-","C61883-","T61884-","T61885-","G61886-","A61887-","A61888-","T61889-","A61890-","A61891-","C61892-","C61893-","T61894-","T61895-","C61896-","A61897-","T61898-","A61899-","G61900-","C61901-","T61902-","A61903-","T61904-","T61905-","T61906-","T61907-","A61908-","A61909-","T61910-","A61911-","G61912-","G61913-","A61914-","T61915-","C61916-","T61917-","A61918-","T61919-","A61920-","T61921-","G61922-","A61923-","T61924-","C61925-","A61926-","G61927-","T61928-","G61929-","T61930-","T61931-","T61932-","A61933-","A61934-","G61935-","C61936-","C61937-","A61938-","T61939-","A61940-","G61941-","C61942-","A61943-","C61944-","A61945-","A61946-","T61947-","T61948-","T61949-","T61950-","C61951-","T61952-","A61953-","A61954-","T61955-","A61956-","C61957-","G61958-","A61959-","G61960-","A61961-","C61962-","G61963-","T61964-","G61965-","A61966-","T61967-","T61968-","T61969-","T61970-","A61971-","T61972-","C61973-","A61974-","A61975-","A61976-","C61977-","A61978-","T61979-","G61980-","A61981-","C61982-","A61983-","T61984-","T61985-","T61986-","T61987-","C61988-","C61989-","T61990-","T61991-","G61992-","T61993-","A61994-","T61995-","C61996-","C61997-","A61998-","T61999-","T62000-","T62001-","C62002-","G62003-","T62004-","T62005-","T62006-","A62007-","A62008-","T62009-","G62010-","A62011-","C62012-","A62013-","A62014-","A62015-","C62016-","A62017-","T62018-","T62019-","T62020-","T62021-","T62022-","G62023-","T62024-","T62025-","G62026-","G62027-","T62028-","G62029-","T62030-","A62031-","A62032-","T62033-","A62034-","A62035-","A62036-","A62037-","A62038-","A62039-","A62040-","A62041-","T62042-","T62043-","A62044-","T62045-","T62046-","T62047-","A62048-","A62049-","T62050-","T62051-","T62052-","T62053-","T62054-","C62055-","A62056-","T62057-","T62058-","A62059-","A62060-","T62061-","A62062-","G62063-","G62064-","G62065-","A62066-","T62067-","T62068-","T62069-","G62070-","A62071-","C62072-","G62073-","T62074-","A62075-","T62076-","G62077-","T62078-","A62079-","G62080-","C62081-","G62082-","T62083-","A62084-","C62085-","A62086-","A62087-","A62088-","A62089-","T62090-","T62091-","A62092-","T62093-","C62094-","G62095-","T62096-","T62097-","C62098-","C62099-","T62100-","G62101-","G62102-","T62103-","A62104-","T62105-","A62106-","T62107-","A62108-","G62109-","A62110-","T62111-","A62112-","A62113-","A62114-","G62115-","A62116-","G62117-","T62118-","C62119-","C62120-","T62121-","A62122-","T62123-","A62124-","T62125-","A62126-","T62127-","T62128-","T62129-","G62130-","A62131-","A62132-","A62133-","A62134-","T62135-","C62136-","G62137-","T62138-","T62139-","A62140-","C62141-","G62142-","G62143-","T62144-","T62145-","C62146-","G62147-","A62148-","T62149-","T62150-","A62151-","A62152-","A62153-","C62154-","T62155-","T62156-","T62157-","A62158-","A62159-","T62160-","G62161-","A62162-","T62163-","T62164-","G62165-","C62166-","A62167-","T62168-","T62169-","G62170-","T62171-","G62172-","A62173-","A62174-","T62175-","A62176-","T62177-","A62178-","T62179-","C62180-","A62181-","T62182-","T62183-","A62184-","G62185-","G62186-","A62187-","T62188-","T62189-","T62190-","A62191-","A62192-","C62193-","T62194-","C62195-","C62196-","T62197-","T62198-","G62199-","A62200-","C62201-","T62202-","A62203-","T62204-","C62205-","A62206-","T62207-","G62208-","G62209-","C62210-","G62211-","G62212-","T62213-","G62214-","C62215-","C62216-","A62217-","G62218-","A62219-","A62220-","A62221-","T62222-","T62223-","A62224-","C62225-","C62226-","A62227-","T62228-","C62229-","A62230-","A62231-","A62232-","A62233-","G62234-","C62235-","A62236-","T62237-","T62238-","A62239-","A62240-","T62241-","A62242-","C62243-","A62244-","G62245-","T62246-","T62247-","A62248-","T62249-","G62250-","C62251-","A62252-","G62253-","A62254-","T62255-","C62256-","G62257-","C62258-","A62259-","G62260-","T62261-","T62262-","A62263-","G62264-","A62265-","A62266-","C62267-","G62268-","G62269-","T62270-","T62271-","A62272-","T62273-","A62274-","G62275-","C62276-","A62277-","T62278-","C62279-","C62280-","A62281-","C62282-","C62283-","A62284-","T62285-","T62286-","T62287-","A62288-","T62289-","A62290-","T62291-","C62292-","T62293-","A62294-","A62295-","A62303-","T62304-","C62305-","A62306-","A62307-","A62308-","G62309-","A62310-","A62311-","T62312-","A62313-","T62314-","G62315-","T62316-","G62317-","A62318-","C62319-","A62320-","A62321-","C62322-","G62323-","T62324-","C62325-","C62326-","T62327-","A62328-","G62329-","T62330-","T62331-","G62332-","T62333-","A62334-","T62335-","A62336-","C62337-","T62338-","G62339-","A62340-","G62341-","A62342-","A62343-","T62344-","T62345-","G62346-","A62347-","C62348-","G62349-","A62350-","A62351-","A62352-","C62353-","A62354-","A62355-","T62356-","G62357-","T62373-","T62374-","T62375-","C62376-","T62377-","T62378-","A62379-","T62380-","T62381-","A62382-","G62383-","T62384-","A62385-","A62386-","C62387-","C62388-","G62389-","A62390-","C62391-","T62392-","T62393-","A62394-","A62395-","T62396-","A62397-","G62398-","T62399-","A62400-","G62401-","G62402-","A62403-","A62404-","C62405-","T62406-","G62407-","G62408-","A62409-","A62410-","A62411-","A62412-","C62413-","T62414-","A62415-","G62416-","A62417-","C62418-","T62419-","T62420-","G62421-","A62422-","T62423-","T62424-","A62425-","T62426-","T62427-","C62428-","T62429-","A62430-","T62431-","A62432-","A62433-","G62434-","T62435-","A62436-","T62437-","A62438-","G62439-","A62440-","T62441-","A62442-","C62443-","C62444-","C62445-","T62446-","T62447-","C62448-","C62449-","A62450-","A62451-","A62452-","T62453-","A62454-","A62455-","T62456-","G62457-","T62458-","T62459-","C62460-","T62461-","C62462-","T62463-","T62464-","T62465-","G62466-","A62467-","T62468-","A62469-","A62470-","A62471-","A62472-","G62473-","T62474-","T62475-","C62476-","C62477-","A62478-","G62479-","A62480-","A62481-","A62482-","A62483-","T62484-","G62485-","T62486-","A62487-","G62488-","A62489-","A62490-","T62491-","T62492-","T62493-","T62494-","T62495-","T62496-","A62497-","A62498-","A62499-","A62500-","A62501-","G62502-","T62503-","T62504-","A62505-","T62506-","C62507-","T62508-","T62509-","T62510-","T62511-","G62512-","C62513-","T62514-","A62515-","T62516-","T62517-","A62518-","C62519-","T62520-","A62521-","A62522-","T62523-","A62524-","T62525-","C62526-","G62527-","T62528-","G62529-","G62530-","T62531-","T62532-","A62533-","G62534-","A62535-","C62536-","G62537-","C62538-","T62539-","T62540-","A62541-","T62542-","T62543-","A62544-","T62545-","T62546-","A62547-","A62548-","T62549-","A62550-","T62551-","G62552-","A62553-","G62554-","T62555-","G62556-","A62557-","T62558-","G62559-","A62560-","A62561-","A62562-","T62563-","C62564-","C62565-","A62566-","C62567-","A62568-","C62569-","C62570-","G62571-","C62572-","T62573-","T62574-","C62575-","T62576-","A62577-","G62578-","A62579-","T62580-","A62581-","T62582-","C62583-","G62584-","C62585-","T62586-","T62587-","T62588-","T62589-","A62590-","T62591-","T62592-","T62593-","C62594-","C62595-","A62596-","C62597-","A62598-","T62599-","T62600-","A62601-","G62602-","A62603-","T62604-","G62605-","G62606-","T62607-","A62608-","A62609-","A62610-","T62611-","C62612-","C62613-","A62614-","A62615-","T62616-","A62617-","G62618-","T62619-","G62620-","A62621-","A62622-","A62623-","C62624-","T62625-","A62626-","T62627-","C62628-","T62629-","T62630-","T62631-","T62632-","T62633-","A62634-","G62635-","G62636-","A62637-","A62638-","T62639-","G62640-","T62641-","A62642-","T62643-","G62644-","G62645-","A62646-","C62647-","T62648-","C62649-","G62650-","C62651-","G62652-","T62653-","T62654-","T62655-","A62656-","G62657-","A62658-","G62659-","G62660-","A62661-","G62662-","T62663-","G62664-","A62665-","A62666-","C62667-","G62668-","T62669-","C62670-","T62671-","T62672-","C62673-","G62674-","G62675-","A62676-","G62677-","T62678-","A62679-","G62680-","T62681-","A62682-","A62683-","A62684-","G62685-","G62686-","A62687-","T62688-","G62689-","A62690-","T62691-","T62692-","C62693-","G62694-","T62695-","C62696-","A62697-","A62698-","A62699-","T62700-","G62701-","A62702-","A62703-","T62704-","A62705-","A62706-","A62707-","C62708-","A62709-","A62710-","T62711-","T62712-","T62713-","C62714-","A62715-","C62716-","A62717-","A62718-","A62719-","T62720-","G62721-","G62722-","A62723-","T62724-","G62725-","T62726-","T62727-","A62728-","A62729-","T62730-","G62731-","T62732-","A62733-","T62734-","T62735-","A62736-","G62737-","T62738-","A62739-","G62740-","G62741-","A62742-","A62743-","A62744-","T62745-","T62746-","T62747-","T62748-","T62749-","T62750-","G62751-","A62752-","C62753-","G62754-","C62755-","T62756-","A62757-","G62758-","T62759-","G62760-","G62761-","A62762-","A62763-","T62764-","T62765-","G62766-","A62767-","A62768-","G62769-","A62770-","T62771-","T62772-","C62773-","T62774-","A62775-","A62776-","T62777-","G62778-","G62779-","A62780-","T62781-","G62782-","A62783-","T62784-","G62785-","T62786-","T62787-","C62788-","T62789-","A62790-","C62791-","C62792-","T62793-","A62794-","T62795-","T62796-","T62797-","C62798-","A62799-","T62800-","C62801-","C62802-","G62803-","A62804-","T62805-","A62806-","A62807-","C62808-","A62809-","T62810-","G62811-","T62812-","T62813-","A62814-","A62815-","T62816-","T62817-","T62818-","C62819-","C62820-","A62821-","A62822-","T62823-","A62824-","C62825-","C62826-","A62827-","A62828-","C62829-","G62830-","G62831-","T62832-","T62833-","T62834-","T62835-","A62836-","A62837-","T62838-","A62839-","T62840-","T62841-","T62842-","C62843-","G62844-","A62845-","T62846-","G62847-","A62848-","T62849-","A62850-","T62851-","A62852-","C62853-","G62854-","G62855-","T62856-","A62857-","G62858-","T62859-","C62860-","T62863-","C62864-","T62865-","T62866-","T62867-","C62868-","G62869-","G62870-","A62871-","C62872-","T62873-","T62874-","A62875-","T62876-","A62877-","T62878-","A62879-","G62880-","C62881-","T62882-","T62883-","A62884-","T62885-","T62886-","C62887-","C62888-","A62889-","C62890-","A62891-","A62892-","T62893-","A62894-","C62895-","G62896-","A62897-","G62898-","T62899-","C62900-","A62901-","T62902-","T62903-","A62904-","T62905-","A62906-","T62907-","A62908-","C62909-","T62910-","C62911-","C62912-","A62913-","A62914-","A62915-","A62916-","A62917-","A62918-","C62919-","A62920-","A62921-","A62922-","A62923-","T62924-","A62925-","A62926-","C62927-","T62928-","A62929-","G62930-","T62931-","A62932-","T62933-","A62934-","A62935-","A62936-","A62937-","T62938-","C62939-","T62940-","G62941-","T62942-","A62943-","T62944-","C62945-","G62946-","A62947-","A62948-","T62949-","G62950-","G62951-","G62952-","A62953-","A62954-","A62955-","A62956-","A62957-","C62958-","G62959-","A62960-","A62961-","A62962-","T62963-","T62964-","A62965-","T62966-","C62967-","G62968-","A62969-","T62970-","A62971-","T62972-","A62973-","G62974-","G62975-","T62976-","A62977-","T62978-","A62979-","G62980-","A62981-","A62982-","T62983-","C62984-","C62985-","G62986-","G62987-","A62988-","A62989-","C62990-","A62991-","T62992-","T62993-","G62994-","A62995-","A62996-","C62997-","G62998-","T62999-","A63000-","T63001-","T63002-","A63003-","A63004-","T63005-","A63006-","C63007-","T63008-","T63009-","A63010-","A63011-","T63012-","T63013-","C63014-","T63015-","T63016-","T63017-","T63018-","T63019-","C63020-","A63021-","G63022-","T63023-","G63024-","G63025-","T63026-","A63027-","A63028-","G63029-","A63030-","A63031-","C63032-","C63033-","G63034-","A63035-","T63036-","A63037-","G63038-","G63039-","T63040-","T63041-","A63042-","T63043-","T63044-","G63045-","A63046-","C63047-","A63048-","T63049-","T63050-","G63051-","T63052-","A63053-","T63054-","G63055-","G63056-","T63057-","T63058-","T63059-","T63060-","A63061-","A63062-","A63063-","T63064-","A63065-","T63066-","T63067-","C63068-","T63069-","A63070-","T63071-","A63072-","A63073-","C63074-","T63075-","T63076-","G63077-","A63078-","G63079-","A63080-","C63081-","T63082-","T63083-","G63084-","A63085-","T63086-","A63087-","G63088-","A63089-","T63090-","A63091-","T63092-","T63093-","A63094-","A63095-","T63096-","G63097-","A63098-","C63099-","G63100-","A63101-","A63102-","T63103-","T63104-","G63105-","A63106-","A63107-","A63108-","A63109-","T63110-","T63111-","A63112-","T63113-","T63114-","T63115-","T63116-","T63117-","A63118-","T63119-","C63120-","A63121-","C63122-","C63123-","A63124-","C63125-","G63126-","T63127-","G63128-","T63129-","G63130-","T63131-","T63132-","T63133-","C63134-","A63135-","G63136-","G63137-","A63138-","T63139-","C63140-","A63141-","T63142-","C63143-","G63144-","T63145-","C63146-","G63147-","A63148-","C63149-","G63150-","C63151-","C63152-","A63153-","G63154-","T63155-","T63156-","A63157-","A63158-","C63159-","C63160-","A63161-","A63162-","C63163-","C63164-","G63165-","A63166-","A63167-","T63168-","G63169-","G63170-","A63171-","G63172-","T63173-","A63174-","A63175-","A63176-","A63177-","T63178-","A63179-","A63180-","A63181-","T63182-","A63183-","T63184-","C63185-","A63186-","T63187-","T63188-","A63189-","A63190-","T63191-","A63192-","T63193-","A63194-","T63195-","G63196-","C63197-","T63198-","C63199-","T63200-","A63201-","G63202-","A63203-","T63204-","A63205-","T63206-","T63207-","A63208-","G63209-","T63210-","A63211-","T63212-","T63213-","T63214-","T63215-","T63216-","A63217-","T63218-","T63219-","A63220-","A63221-","T63222-","C63223-","C63224-","T63225-","T63226-","T63227-","G63228-","A63229-","T63230-","T63231-","A63232-","T63233-","C63234-","A63235-","T63236-","C63237-","T63238-","T63239-","C63240-","T63241-","C63242-","G63243-","T63244-","A63245-","C63246-","G63247-","C63248-","G63249-","A63250-","A63251-","T63252-","G63253-","A63254-","T63255-","T63256-","C63257-","C63258-","A63259-","T63260-","G63261-","A63262-","T63263-","C63264-","A63265-","A63266-","G63267-","A63268-","G63269-","T63270-","G63271-","A63272-","T63273-","T63274-","T63275-","G63276-","A63277-","G63278-","A63279-","A63280-","C63281-","A63282-","T63283-","C63284-","C63285-","T63286-","C63287-","C63288-","G63289-","G63290-","A63291-","G63292-","T63293-","A63294-","T63295-","T63296-","A63297-","A63298-","T63299-","G63300-","G63301-","G63302-","T63303-","T63304-","T63305-","A63306-","G63307-","T63308-","A63309-","A63310-","A63311-","C63312-","A63313-","G63314-","T63315-","C63316-","C63317-","A63318-","T63319-","C63320-","G63321-","T63322-","T63323-","G63324-","C63325-","A63326-","A63327-","T63328-","A63329-","A63330-","T63331-","A63332-","A63333-","A63334-","A63335-","G63336-","T63337-","T63338-","G63339-","T63340-","C63341-","C63342-","A63343-","A63344-","G63345-","T63346-","T63347-","A63348-","A63349-","A63350-","G63351-","G63352-","A63353-","T63354-","A63355-","T63356-","T63357-","A63358-","T63359-","G63360-","C63361-","A63362-","T63363-","T63364-","C63365-","G63366-","T63367-","T63368-","T63369-","A63370-","A63371-","A63372-","G63373-","A63374-","T63375-","A63376-","T63377-","C63378-","A63379-","C63380-","C63381-","T63382-","C63383-","A63384-","T63385-","C63386-","T63387-","A63388-","A63389-","C63390-","G63391-","G63392-","A63393-","G63394-","A63395-","C63396-","A63397-","A63398-","T63399-","T63400-","T63401-","T63402-","T63403-","T63404-","G63405-","G63406-","T63407-","A63408-","G63409-","G63410-","T63411-","T63412-","T63413-","T63414-","A63415-","G63416-","A63417-","G63418-","A63419-","C63420-","T63421-","T63422-","T63423-","G63424-","A63425-","A63426-","G63427-","C63428-","T63429-","A63430-","C63431-","T63432-","T63433-","G63434-","T63435-","T63436-","T63437-","A63438-","A63439-","C63440-","A63441-","A63442-","A63443-","G63444-","T63445-","T63446-","A63447-","T63448-","T63449-","C63450-","A63451-","T63452-","C63453-","G63454-","T63455-","C63456-","G63457-","T63458-","C63459-","T63460-","A63461-","C63462-","T63463-","A63464-","T63465-","T63466-","C63467-","T63468-","A63469-","T63470-","T63471-","T63472-","A63473-","A63474-","T63475-","T63476-","T63477-","T63478-","G63479-","T63480-","A63481-","G63482-","T63483-","T63484-","A63485-","A63486-","T63487-","T63488-","T63489-","A63490-","T63491-","C63492-","A63493-","C63494-","A63495-","T63496-","A63497-","T63498-","C63499-","A63500-","C63501-","A63502-","T63503-","T63504-","A63505-","A63506-","A89103-","A89104-","A89105-","G89148-","T89149-","C89150-","A89151-","T89166-","C89229-","A89230-","G89231-","T89232-","G89233-","T89234-","T89235-","A89373-","C89374-","T89375-","T89376-","A89377-","T89378-","A89379-","T89380-","T89381-","C89382-","G89383-","T89384-","G89385-","T89386-","C89387-","T89388-","A89389-","G89390-","T89391-","A89392-","G89393-","A89394-","T89700-","A194548-","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","C194595-","G194596-","T194597-","G194598-","T194599-"],"OPG002":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-"],"OPG002_dup":["C44-","L45-","S46-","C47-"],"OPG057":["N267D"],"OPG082":["T259-","P260-","K261-","T262-","F263-","T264-","P265-","L266-","N267-","A268-","S269-","P270-","V277-","F328-","I329-","K330-","E331-","N332-","I333-","I334-","W335-","K336-","G337-","I338-","Y339-","T340-","F348-","P349-","V350-","P351-","T352-","T357-","N358-","K359-","K360-","K361-","V369-","N370-","S371-","Q372-"]},"labels":{"aa":"OPG002: K31-, C32-, K33-, D34-, N35-, E36-, Y37-; OPG002_dup: C44-, L45-, S46-, C47-; OPG057: N267D; OPG082: T259-, P260-, K261-, T262-, F263-, T264-, P265-, L266-, N267-, A268-, S269-, P270-, V277-, F328-, I329-, K330-, E331-, N332-, I333-, I334-, W335-, K336-, G337-, I338-, Y339-, T340-, F348-, P349-, V350-, P351-, T352-, T357-, N358-, K359-, K360-, K361-, V369-, N370-, S371-, Q372-"}},"children":[{"name":"OQ672577","node_attrs":{"div":7,"accession":"OQ672577","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"13022023_anal"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672577/2023-02-13"},"date":{"value":"2023-02-13"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-61794G","-61795G","-61796C","-61797A","-61798T","-61815A","-61816G","-61817T","-61818A","-61819C","-61820A","-61821A","-61822G","-61823T","-61824G","-61825G","-61826C","-61827T","-61828G","-61829C","-61830T","-61831A","-61832T","-61833T","-61834T","-61835C","-61836G","-61837G","-61838C","-61839T","-61840G","-61841C","-61842C","-61843A","-61844G","-61845A","-61846G","-61847T","-61848G","-61849T","-61850C","-61851C","-61852A","-61853A","-61854T","-61855T","-61856C","-61857T","-61858A","-61859C","-61860C","-61861G","-61862T","-61863T","-61864G","-61865T","-61866T","-61867A","-61868C","-61869T","-61870C","-61871C","-61872A","-61873T","-61874T","-61875A","-61876T","-61877A","-61878T","-61879A","-61880T","-61881T","-61882C","-61883C","-61884T","-61885T","-61886G","-61887A","-61888A","-61889T","-61890A","-61891A","-61892C","-61893C","-61894T","-61895T","-61896C","-61897A","-61898T","-61899A","-61900G","-61901C","-61902T","-61903A","-61904T","-61905T","-61906T","-61907T","-61908A","-61909A","-61910T","-61911A","-61912G","-61913G","-61914A","-61915T","-61916C","-61917T","-61918A","-61919T","-61920A","-61921T","-61922G","-61923A","-61924T","-61925C","-61926A","-61927G","-61928T","-61929G","-61930T","-61931T","-61932T","-61933A","-61934A","-61935G","-61936C","-61937C","-61938A","-61939T","-61940A","-61941G","-61942C","-61943A","-61944C","-61945A","-61946A","-61947T","-61948T","-61949T","-61950T","-61951C","-61952T","-61953A","-61954A","-61955T","-61956A","-61957C","-61958G","-61961A","-61962C","-61963G","-61964T","-61965G","-61966A","-61967T","-61968T","-61969T","-61970T","-61971A","-61972T","-61973C","-61974A","-61975A","-61976A","-61977C","-61978A","-61979T","-61980G","-61981A","-61982C","-61983A","-61984T","-61985T","-61986T","-61987T","-61988C","-61989C","-61990T","-61991T","-61992G","-61993T","-61994A","-61995T","-61996C","-61997C","-61998A","-61999T","-62000T","-62001T","-62002C","-62003G","-62004T","-62005T","-62006T","-62007A","-62008A","-62009T","-62010G","-62011A","-62012C","-62013A","-62014A","-62015A","-62016C","-62017A","-62018T","-62019T","-62020T","-62021T","-62022T","-62023G","-62024T","-62025T","-62026G","-62027G","-62028T","-62029G","-62030T","-62031A","-62032A","-62033T","-62034A","-62035A","-62036A","-62037A","-62038A","-62039A","-62040A","-62041A","-62042T","-62043T","-62044A","-62045T","-62046T","-62047T","-62048A","-62049A","-62050T","-62051T","-62052T","-62053T","-62054T","-62055C","-62056A","-62057T","-62058T","-62059A","-62060A","-62061T","-62062A","-62064G","-62066A","-62067T","-62068T","-62069T","-62070G","-62071A","-62072C","-62073G","-62074T","-62075A","-62076T","-62077G","-62078T","-62079A","-62080G","-62081C","-62082G","-62083T","-62084A","-62085C","-62086A","-62087A","-62088A","-62089A","-62090T","-62091T","-62092A","-62093T","-62094C","-62095G","-62096T","-62097T","-62098C","-62099C","-62100T","-62101G","-62102G","-62103T","-62104A","-62105T","-62106A","-62107T","-62108A","-62109G","-62110A","-62111T","-62112A","-62113A","-62114A","-62115G","-62116A","-62117G","-62118T","-62119C","-62120C","-62121T","-62122A","-62123T","-62124A","-62125T","-62126A","-62127T","-62128T","-62129T","-62130G","-62131A","-62132A","-62133A","-62134A","-62135T","-62136C","-62137G","-62138T","-62139T","-62140A","-62141C","-62142G","-62143G","-62144T","-62145T","-62146C","-62147G","-62148A","-62149T","-62150T","-62151A","-62152A","-62153A","-62154C","-62155T","-62156T","-62157T","-62158A","-62159A","-62160T","-62161G","-62162A","-62163T","-62164T","-62165G","-62166C","-62167A","-62168T","-62169T","-62170G","-62171T","-62172G","-62173A","-62174A","-62175T","-62176A","-62177T","-62178A","-62179T","-62180C","-62181A","-62182T","-62183T","-62184A","-62185G","-62186G","-62187A","-62188T","-62189T","-62190T","-62191A","-62192A","-62193C","-62194T","-62195C","-62196C","-62197T","-62198T","-62199G","-62200A","-62201C","-62202T","-62203A","-62204T","-62205C","-62206A","-62207T","-62208G","-62209G","-62210C","-62211G","-62212G","-62213T","-62214G","-62215C","-62216C","-62217A","-62221A","-62222T","-62223T","-62228T","-62229C","-62230A","-62231A","-62232A","-62233A","-62234G","-62235C","-62236A","-62237T","-62238T","-62239A","-62240A","-62241T","-62242A","-62243C","-62244A","-62245G","-62246T","-62247T","-62248A","-62249T","-62250G","-62251C","-62252A","-62253G","-62254A","-62255T","-62256C","-62257G","-62258C","-62259A","-62260G","-62264G","-62265A","-62266A","-62267C","-62268G","-62269G","-62270T","-62271T","-62272A","-62273T","-62274A","-62275G","-62276C","-62277A","-62278T","-62279C","-62280C","-62281A","-62282C","-62283C","-62284A","-62285T","-62286T","-62287T","-62288A","-62289T","-62290A","-62303A","-62304T","-62309G","-62310A","-62311A","-62312T","-62313A","-62314T","-62315G","-62316T","-62317G","-62318A","-62319C","-62320A","-62321A","-62322C","-62324T","-62325C","-62326C","-62327T","-62328A","-62329G","-62330T","-62331T","-62332G","-62333T","-62352A","-62353C","-62354A","-62355A","-62356T","-62357G","-62389G","-62390A","-62391C","-62392T","-62393T","-62413C","-62414T","-62416G","-62417A","-62420T","-62421G","-62422A","-62423T","-62424T","-62425A","-62426T","-62427T","-62428C","-62429T","-62430A","-62431T","-62432A","-62474T","-62475T","-62484T","-62492T","-62493T","-62494T","-62495T","-62496T","-62497A","-62498A","-62499A","-62500A","-62501A","-62502G","-62503T","-62504T","-62505A","-62506T","-62507C","-62508T","-62509T","-62510T","-62511T","-62512G","-62513C","-62514T","-62515A","-62516T","-62517T","-62518A","-62519C","-62520T","-62521A","-62522A","-62523T","-62524A","-62525T","-62526C","-62527G","-62528T","-62529G","-62530G","-62531T","-62532T","-62543T","-62546T","-62547A","-62548A","-62549T","-62550A","-62551T","-62552G","-62553A","-62554G","-62555T","-62556G","-62557A","-62558T","-62559G","-62560A","-62561A","-62562A","-62563T","-62564C","-62565C","-62566A","-62567C","-62568A","-62569C","-62570C","-62571G","-62572C","-62573T","-62575C","-62579A","-62580T","-62581A","-62582T","-62583C","-62584G","-62585C","-62586T","-62587T","-62588T","-62589T","-62590A","-62591T","-62592T","-62593T","-62594C","-62595C","-62596A","-62597C","-62598A","-62599T","-62600T","-62601A","-62602G","-62606G","-62607T","-62608A","-62609A","-62610A","-62611T","-62612C","-62616T","-62617A","-62618G","-62619T","-62620G","-62621A","-62627T","-62632T","-62633T","-62634A","-62635G","-62636G","-62637A","-62638A","-62639T","-62640G","-62641T","-62642A","-62643T","-62653T","-62694G","-62695T","-62697A","-62698A","-62700T","-62705A","-62706A","-62707A","-62708C","-62709A","-62710A","-62711T","-62712T","-62713T","-62714C","-62715A","-62716C","-62717A","-62718A","-62719A","-62720T","-62721G","-62722G","-89103A","-89104A","-89105A","-89148G","-89149T","-89150C","-89151A","-89229C","-89230A","-89231G","-89232T","-89233G","-89234T","-89235T","-89373A","-89374C","-89375T","-89376T","-89377A","-89378T","-89379A","-89380T","-89381T","-89382C","-89383G","-89384T","-89385G","-89386T","-89387C","-89388T","-89389A","-89390G","-89391T","-89392A","-89393G","-89394A","-89700T","C194600-","C194601-","T194602-"],"OPG002_dup":["P48-"]},"labels":{"aa":"OPG002_dup: P48-"}}},{"name":"OQ672576","node_attrs":{"div":8,"accession":"OQ672576","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"08022023_anal"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672576/2023-02-08"},"date":{"value":"2023-02-08"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T70389G","-194548A"],"OPG089":["M175R"]},"labels":{"aa":"OPG089: M175R"}}},{"name":"OQ672579","node_attrs":{"div":7,"accession":"OQ672579","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"28022023_anal"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672579/2023-02-28"},"date":{"value":"2023-02-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-62294A","-62374T","-62375T","-63506A","C70785-","G70786-","T70787-","A70788-","T70789-","A70790-","T70829-","C70830-","G70880-","T70881-","G70882-","C70883-","C70884-","G70885-","T70886-","T70887-","A70888-","C70889-","C70890-","C70891-","T70892-","G70893-","C70894-","C70895-","G70907-","C70908-","A70909-","T70910-","T70911-","A70912-","G70913-","A70914-","A70915-","C70916-","C70917-","A70918-","C70919-","G70920-","T70921-","G70940-","A70941-","A70942-","T70963-","T70970-","T70971-","C70972-","G70973-","A70974-","A70975-","A70976-","A70977-","T70978-","A70979-","C70980-","T70981-","A70982-","A70983-","A70984-","T70985-","C70986-","A70987-","T71023-","G71024-","G71025-","A71026-","T71027-","A71028-","T71029-","T71030-","C71031-","T71032-","A71033-","A71034-","C71035-","G71036-","A71037-","A71038-","A71039-","A71040-","C71041-","T71042-","G71043-","T71044-","A71045-","A71046-","C71047-","A71048-","C71049-","C71050-","A71051-","T71052-","A71053-","G71054-","T71055-","G71056-","T71057-","T71058-","C71059-","G71060-","G71061-","C71062-","A71063-","T71064-","C71065-","T71066-","A71067-","T71068-","A71069-","A71070-","G71071-","G71072-","A71073-","T71074-","A71075-","A71076-","T71077-","T71078-","T71079-","A71080-","C71081-","T71082-","A71083-","C71084-","T71085-","G71086-","A71087-","G71088-","T71089-","A71090-","T71091-","A71092-","A71129-","C71130-","C71131-","A71132-","A71133-","T71134-","A71135-","C71136-","T71137-","A71138-","A71139-","A71140-","A71141-","G71142-","T71143-","G71144-","A71145-","T71146-","A71147-","A71148-","T71149-","A71150-","T71172-","T71173-","A71174-","A71175-","A71176-","A71177-","A71178-","A71179-","T71180-","G71181-","G71182-","T71183-","G71184-","T71185-","T71186-","C71187-","C71188-","A71189-","G71190-","C71191-","T71192-","C71193-","G71194-","T71195-","G71196-","T71197-","G71198-","T71199-","T71200-","C71201-","T71202-","A71203-","C71204-","A71205-","T71206-","G71207-","C71208-","G71209-","G71210-","C71211-","A71212-","A71213-","A71214-","G71215-","A71216-","T71217-","A71218-","T71219-","T71220-","T71221-","C71222-","T71223-","C71224-","A71225-","C71226-","G71227-","A71228-","A71229-","C71230-","G71231-","A71232-","T71233-","A71234-","T71235-","A71236-","A71237-","A71238-","T71239-","T71240-","G71241-","A71242-","T71243-","T71244-","A71245-","T71246-","A71247-","C71248-","G71249-","A71250-","A71251-","A71252-","A71253-","A71254-","A71255-","A71256-","T71257-","C71258-","A71259-","T71260-","T71261-","A71262-","A71263-","A71264-","G71265-","G71266-","A71267-","T71268-","G71269-","T71270-","A71271-","C71272-","T71273-","A71274-","G71275-","T71276-","C71277-","A71278-","G71279-","T71280-","G71281-","T71282-","A71283-","A71284-","A71285-","G71286-","A71287-","A71288-","C71289-","G71290-","A71291-","A71292-","T71293-","G71294-","T71295-","T71296-","G71297-","T71298-","A71299-","G71300-","G71301-","T71302-","T71303-","A71304-","A71305-","A71306-","A71307-","T71308-","T71309-","A71310-","T71311-","C71312-","T71313-","A71314-","C71315-","A71316-","C71317-","A71318-","A71319-","A71320-","T71321-","A71322-","G71323-","A71324-","A71325-","C71326-","C71327-","T71328-","C71329-","A71330-","A71331-","C71332-","G71333-","T71334-","A71335-","A71336-","C71337-","T71338-","T71339-","A71340-","A71341-","C71342-","A71343-","G71344-","T71345-","G71346-","C71347-","A71348-","A71349-","C71350-","C71351-","T71352-","C71353-","T71354-","A71355-","T71356-","T71357-","G71358-","G71359-","A71360-","T71361-","A71362-","T71363-","A71364-","A71365-","A71366-","C71367-","T71368-","A71369-","A71370-","T71371-","G71372-","G71373-","A71374-","T71375-","C71376-","C71377-","G71378-","G71379-","T71380-","T71381-","A71382-","A71383-","T71384-","T71385-","T71386-","T71387-","A71388-","T71389-","C71390-","A71391-","A71392-","G71393-","A71394-","C71395-","A71396-","T71397-","A71398-","T71399-","G71400-","C71401-","G71402-","C71403-","C71404-","T71405-","A71406-","G71407-","A71408-","G71409-","G71410-","T71411-","T71412-","C71413-","T71414-","A71415-","T71416-","T71417-","A71418-","T71419-","T71420-","T71421-","T71422-","T71423-","A71424-","T71425-","T71426-","G71517-","T71518-","A71519-","G71520-","T71521-","T71522-","G71523-","A71524-","A71525-","T71526-","C71527-","T71528-","A71529-","C71530-","C71531-","T71532-","A71533-","T71534-","A71535-","G71536-","A71537-","A71538-","A71539-","A71540-","G71541-","G71542-","A71543-","G71544-","T71545-","T71546-","A71547-","G71548-","A71549-","A71550-","T71551-","A71552-","G71553-","T71554-","C71555-","C71556-","C71557-","A71558-","T71559-","T71560-","G71561-","G71562-","A71563-","T71564-","A71565-","G71566-","A71567-","T71568-","T71569-","T71570-","T71571-","T71572-","T71573-","G71574-","A71575-","A71576-","G71577-","G71578-","A71579-","T71580-","A71581-","T71582-","C71583-","T71584-","T71585-","A71586-","G71587-","T71588-","G71589-","C71590-","A71591-","A71592-","A71593-","A71594-","G71595-","T71596-","A71597-","T71598-","A71599-","C71600-","A71601-","T71602-","G71603-","T71604-","T71605-","A71606-","G71607-","A71608-","G71609-","A71610-","A71611-","T71612-","A71613-","T71614-","T71615-","C71616-","A71617-","A71618-","G71619-","T71620-","T71621-","A71622-","T71623-","G71624-","A71625-","A71626-","A71627-","A71628-","T71629-","A71630-","G71631-","C71632-","A71633-","G71634-","C71635-","T71636-","G71637-","A71638-","T71639-","A71640-","T71641-","G71642-","T71643-","C71644-","G71645-","T71646-","T71647-","A71648-","A71649-","C71650-","T71651-","T71652-","G71676-","G71677-","T71678-","C71679-","G71709-","C71710-","T71711-","G71712-","A71713-","A71714-","T71715-","G71716-","T71717-","T71718-","A71719-","T71720-","A71721-","A71722-","A71723-","A71724-","A71725-","T71726-","G71727-","C71728-","C71729-","G71730-","G71731-","T71732-","A71733-","T71734-","T71735-","G71736-","A71737-","T71738-","A71739-","C71740-","A71741-","T71742-","C71743-","G71744-","T71745-","C71746-","T71747-","A71748-","A71749-","A71750-","C71751-","G71752-","A71753-","A71754-","T71755-","A71756-","T71757-","T71758-","A71759-","G71760-","G71761-","T71762-","A71763-","A71764-","A71765-","G71766-","A71767-","T71768-","A71769-","T71770-","T71771-","T71772-","T71773-","T71774-","C71775-","T71776-","G71777-","A71778-","G71779-","C71780-","C71781-","A71782-","A71783-","A71784-","A71785-","C71786-","T71787-","T71788-","T71789-","A71790-","C71791-","A71792-","G71793-","A71794-","T71795-","G71796-","A71797-","T71798-","A71799-","A71800-","T71801-","A71802-","G71803-","A71804-","T71805-","G71806-","G71807-","A71808-","T71809-","A71810-","A71811-","A71812-","G71813-","C71856-","C71910-","T71911-","T71912-","T71913-","T71914-","T71915-","C71916-","T71917-","T71918-","A71919-","A71920-","C71921-","G71922-","T71923-","T71924-","G71925-","T71926-","T71927-","T71928-","G71929-","C71930-","C71931-","A71932-","T71933-","C71934-","A71935-","C71936-","T71937-","C71938-","T71939-","C71940-","A71941-","T71942-","A71943-","A71944-","T71945-","G71946-","T71947-","A71948-","A71949-","A71950-","G71951-","A71952-","T71953-","A71954-","T71955-","T71956-","C71957-","T71958-","A71959-","A71960-","A71961-","A71962-","T71963-","G71964-","G71965-","T71966-","A71967-","A71968-","A71969-","C71970-","T71971-","T71972-","T71973-","T71974-","G71975-","C71976-","A71977-","T71978-","A71979-","T71980-","C71981-","G71982-","G71983-","A71984-","T71985-","G71986-","C71987-","A71988-","G71989-","A71990-","A71991-","A71992-","T71993-","T71994-","G71995-","G71996-","T71997-","A71998-","T71999-","A72000-","A72001-","A72002-","T72003-","G72004-","T72005-","T72006-","G72007-","T72008-","A72009-","A72010-","T72011-","T72012-","G72013-","T72014-","A72015-","T72016-","T72017-","A72018-","T72019-","T72020-","T72021-","C72022-","C72023-","C72024-","G72025-","T72026-","C72027-","A72028-","A72029-","T72030-","G72031-","G72032-","A72033-","C72034-","T72035-","A72036-","G72037-","T72038-","C72039-","A72040-","C72041-","A72042-","G72043-","C72044-","T72045-","C72046-","C72047-","A72048-","T72049-","C72050-","A72051-","G72052-","T72053-","T72054-","T72055-","T72056-","A72057-","T72058-","A72059-","T72060-","C72061-","C72062-","T72063-","T72064-","T72065-","A72066-","G72067-","A72068-","G72069-","T72070-","A72071-","T72072-","T72073-","T72074-","C72075-","T72076-","C72077-","A72078-","C72079-","T72080-","C72081-","G72082-","T72083-","G72084-","T72085-","C72086-","T72087-","A72088-","G72089-","C72090-","A72091-","T72092-","T72093-","C72094-","T72095-","A72096-","G72097-","A72098-","G72099-","C72100-","A72101-","T72102-","T72103-","C72104-","C72105-","A72106-","T72107-","G72108-","A72109-","T72110-","C72111-","T72112-","G72113-","T72114-","T72115-","T72116-","A72117-","T72118-","C72119-","G72120-","T72121-","T72122-","G72123-","A72124-","T72125-","A72126-","T72127-","T72128-","G72129-","G72130-","C72131-","C72132-","G72133-","G72134-","A72135-","A72136-","A72137-","G72138-","A72139-","T72140-","A72141-","G72142-","A72143-","T72144-","T72145-","T72146-","T72147-","T72148-","T72149-","A72150-","T72151-","T72152-","T72153-","T72154-","T72155-","T72156-","A72157-","T72158-","T72159-","A72160-","T72161-","A72162-","T72163-","T72164-","A72165-","C72166-","T72167-","A72168-","T72169-","T72170-","G72171-","G72172-","C72173-","A72174-","A72175-","T72176-","T72177-","G72178-","T72179-","A72180-","G72181-","A72182-","T72183-","A72184-","T72185-","A72186-","A72187-","C72188-","T72189-","T72190-","C72191-","T72192-","G72193-","G72194-","T72195-","A72196-","A72197-","A72198-","T72199-","A72200-","T72201-","T72202-","T72203-","T72204-","T72205-","C72206-","T72207-","A72208-","C72209-","C72210-","T72211-","T72212-","T72213-","T72214-","C72215-","A72216-","A72217-","T72218-","C72219-","T72220-","C72221-","T72222-","T72223-","C72224-","T72225-","A72226-","T72227-","T72228-","T72229-","T72230-","C72231-","A72232-","A72233-","G72234-","C72235-","C72236-","G72237-","G72238-","C72239-","T72240-","A72241-","T72242-","A72243-","T72244-","A72245-","T72246-","T72247-","C72248-","T72249-","G72250-","C72251-","T72252-","A72253-","T72254-","A72255-","T72256-","T72257-","G72258-","T72259-","T72260-","A72261-","C72262-","T72263-","A72264-","G72265-","T72266-","A72267-","T72268-","C72269-","A72270-","A72271-","T72272-","A72273-","C72274-","C72275-","T72276-","T72277-","T72278-","T72279-","C72280-","T72281-","G72282-","G72283-","C72284-","T72285-","A72286-","A72287-","G72288-","A72289-","A72290-","G72291-","T72292-","C72293-","A72294-","T72295-","A72296-","T72297-","G72298-","T72299-","G72300-","G72301-","T72302-","A72303-","T72304-","T72305-","C72306-","A72307-","C72308-","T72309-","A72310-","T72311-","A72312-","T72313-","C72314-","A72315-","G72316-","T72317-","T72318-","T72319-","T72320-","A72321-","A72322-","C72323-","T72324-","G72325-","G72326-","T72327-","A72328-","G72329-","T72330-","T72331-","C72332-","C72333-","A72334-","T72335-","T72336-","A72337-","G72338-","C72339-","C72340-","T72341-","T72342-","T72343-","C72344-","C72345-","A72346-","C72347-","T72348-","T72349-","C72350-","T72351-","G72352-","C72353-","A72354-","G72355-","A72356-","A72357-","T72358-","A72359-","A72360-","T72361-","T72362-","A72363-","G72364-","A72365-","A72366-","A72367-","T72368-","T72369-","G72370-","G72371-","T72372-","T72373-","C72374-","T72375-","T72376-","T72377-","A72378-","C72379-","C72380-","A72381-","G72382-","A72383-","A72384-","A72385-","A72386-","T72387-","C72388-","C72389-","A72390-","G72391-","C72392-","T72393-","A72394-","-194548A","-194549A"],"OPG080":["A75-"],"OPG089":["S307F","I309-","P310-","S322-","V339-","P340-","L341-","P342-","C343-","Q344-","L349-","E350-","P351-","R352-","K353-","E359-"],"OPG091":["L163-"],"OPG092":["A186-","G187-","F188-","S189-","G190-","K191-","E192-","P193-","I194-","S195-","N196-","Y197-","S198-","A199-","E200-","V201-","E202-","R203-","L204-","M205-","E206-","L207-","P208-","V209-","K210-","T211-","D212-","I213-","V214-","N215-","T216-","T217-","Y218-","D219-","F220-","L221-","A222-","R223-","K224-","G225-","I226-","D227-","T228-","S229-","N230-","N231-","I232-","A233-","E234-","Y235-","I236-","A237-","G238-","L239-","K240-","I241-","E242-","E243-","I244-","E245-","K246-","V247-","E248-","K249-","Y250-","L251-","P252-","E253-","V254-","I255-","S256-","T257-","I258-","A259-","N260-","S261-","N262-","I263-","I264-","K265-","N266-","K267-","K268-","S269-","I270-","F271-","P272-","A273-","N274-","I275-","N276-","D277-","K278-","Q279-","I280-","M281-","E282-","C283-","S284-","R285-","M286-","L287-","D288-","T289-","S290-","E291-","K292-","Y293-","S294-","K295-","G296-","Y297-","K298-","T299-","D300-","G301-","A302-","V303-","T304-","S305-","P306-","L307-","T308-","G309-","N310-","N311-","T312-","I313-","T314-","T315-","F316-","I317-","P318-","I319-","S320-","A321-","S322-","D323-","M324-","Q325-","K326-","F327-","T328-","I329-","L330-","E331-","Y332-","L333-","Y334-","I335-","M336-","R337-","V338-","M339-","A340-","N341-","N342-","V343-","K344-","K345-","K346-","V365-"],"OPG109":["L19-","L20-","D21-","T22-","N23-","I24-","S25-","D100-"]},"labels":{"aa":"OPG080: A75-; OPG089: S307F, I309-, P310-, S322-, V339-, P340-, L341-, P342-, C343-, Q344-, L349-, E350-, P351-, R352-, K353-, E359-; OPG091: L163-; OPG092: A186-, G187-, F188-, S189-, G190-, K191-, E192-, P193-, I194-, S195-, N196-, Y197-, S198-, A199-, E200-, V201-, E202-, R203-, L204-, M205-, E206-, L207-, P208-, V209-, K210-, T211-, D212-, I213-, V214-, N215-, T216-, T217-, Y218-, D219-, F220-, L221-, A222-, R223-, K224-, G225-, I226-, D227-, T228-, S229-, N230-, N231-, I232-, A233-, E234-, Y235-, I236-, A237-, G238-, L239-, K240-, I241-, E242-, E243-, I244-, E245-, K246-, V247-, E248-, K249-, Y250-, L251-, P252-, E253-, V254-, I255-, S256-, T257-, I258-, A259-, N260-, S261-, N262-, I263-, I264-, K265-, N266-, K267-, K268-, S269-, I270-, F271-, P272-, A273-, N274-, I275-, N276-, D277-, K278-, Q279-, I280-, M281-, E282-, C283-, S284-, R285-, M286-, L287-, D288-, T289-, S290-, E291-, K292-, Y293-, S294-, K295-, G296-, Y297-, K298-, T299-, D300-, G301-, A302-, V303-, T304-, S305-, P306-, L307-, T308-, G309-, N310-, N311-, T312-, I313-, T314-, T315-, F316-, I317-, P318-, I319-, S320-, A321-, S322-, D323-, M324-, Q325-, K326-, F327-, T328-, I329-, L330-, E331-, Y332-, L333-, Y334-, I335-, M336-, R337-, V338-, M339-, A340-, N341-, N342-, V343-, K344-, K345-, K346-, V365-; OPG109: L19-, L20-, D21-, T22-, N23-, I24-, S25-, D100-"}}},{"name":"OQ672578","node_attrs":{"div":7,"accession":"OQ672578","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"23022023_anal"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672578/2023-02-23"},"date":{"value":"2023-02-23"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T2662-","C47694-","T49712-","G61626-","A61627-","G61628-","C61629-","T61630-","T61631-","A61674-","A61675-","T61676-","C61677-","G61678-","G61679-","A61680-","G61681-","A61682-","A61683-","T61684-","G61685-","T61686-","T61687-","T61688-","C61689-","C61690-","C61691-","A61692-","T61693-","T61694-","T61695-","T61696-","T61697-","A61698-","G61699-","G61700-","A61701-","T61702-","T61703-","A61704-","A61705-","C61706-","A61707-","T61708-","A61709-","G61710-","T61740-","A61741-","G61742-","T61743-","T61744-","A61764-","T61765-","T61766-","T61767-","G61768-","A61769-","T61770-","A61771-","A61791-","A61792-","T61793-","A61799-","A61800-","T61801-","C61802-","C61803-","G61804-","G61805-","A61806-","T61807-","G61808-","T61809-","T61810-","G61811-","T61812-","G61813-","T61814-","A62296-","A62297-","A62298-","T62299-","T62300-","A62301-","G62302-","T62358-","T62359-","T62360-","C62361-","T62362-","T62363-","A62364-","C62365-","A62366-","T62367-","A62368-","T62369-","T62370-","T62371-","T62372-","G88521-","A88522-","T88523-","C88524-","T88525-","C88526-","T88527-","A88528-","T88529-","A88530-","A88531-","T88532-","A88533-","T88534-","C88535-","T88536-","A88537-","G88538-","T88539-","T88540-","T88541-","C88542-","T88543-","T88544-","G88545-","C88546-","G88547-","T88548-","T88549-","T88550-","C88551-","A88552-","C88553-","A88554-","A88555-","A88556-","C88557-","A88558-","C88559-","A88560-","G88561-","G88562-","C88563-","T88564-","C88565-","G88566-","T88567-","C88568-","T88569-","C88570-","T88571-","C88572-","G88573-","C88574-","G88575-","A88576-","T88577-","G88578-","A88579-","G88580-","A88581-","T88582-","C88583-","T88584-","G88585-","T88586-","A88587-","T88588-","A88589-","G88590-","T88591-","A88592-","A88593-","C88594-","T88595-","A88596-","T88597-","G88598-","T88599-","A88600-","A88601-","A88602-","T88603-","G88604-","A88605-","T88606-","A88607-","A88608-","C88609-","T88610-","A88611-","G88612-","A88613-","T88614-","A88615-","G88616-","A88617-","A88618-","A88619-","G88620-","A88621-","T88622-","G88623-","T88624-","A88625-","G88626-","C88627-","T88628-","A88629-","T88630-","A88631-","T88632-","A88633-","G88634-","A88635-","T88636-","G88637-","A88638-","C88639-","G88640-","A88641-","T88642-","C88643-","C88644-","T88645-","T88646-","T88647-","A88648-","A88649-","G88650-","A88651-","G88652-","A88653-","G88654-","G88655-","T88656-","A88657-","T88658-","A88659-","A88660-","T88661-","A88662-","A88663-","C88664-","T88665-","T88666-","T88667-","A88668-","C88669-","C88670-","C88671-","C88672-","A88673-","A88674-","T88675-","C88676-","A88677-","G88678-","A88679-","T88680-","A88681-","G88682-","A88683-","C88684-","T88685-","G88686-","T88687-","T88688-","G88689-","T88690-","T88691-","A88692-","T88693-","G88694-","G88695-","T88696-","C88697-","T88698-","T88699-","C88700-","G88701-","G88702-","A88703-","A88704-","A88705-","A88706-","A88707-","G88708-","A88709-","A88710-","T88711-","T88712-","T88713-","T88714-","T88715-","A88716-","T88717-","A88718-","A88719-","A88720-","T88721-","T88722-","T88723-","T88724-","T88725-","C88726-","C88727-","A88728-","G88729-","T88730-","A88731-","T88732-","T88733-","T88734-","T88735-","C88736-","T88737-","A88738-","A88739-","A88740-","T88741-","A88742-","T88743-","A88744-","C88745-","G88746-","T88747-","A88748-","C88749-","T88750-","T88751-","G88752-","A88753-","T88754-","A88755-","T88756-","C88757-","T88758-","A88759-","A88760-","G88761-","A88762-","A88763-","A88764-","T88765-","C88766-","C88767-","T88768-","T88769-","A88770-","A88771-","T88772-","A88773-","A88774-","T88775-","A88776-","A88777-","T88778-","A88779-","G88780-","G88781-","A88782-","A88783-","T88784-","G88785-","G88786-","A88787-","T88788-","A88789-","A88790-","T88791-","C88792-","C88793-","G88794-","T88795-","C88796-","T88797-","A88798-","T88799-","T88800-","T88801-","T88802-","A88803-","T88804-","A88805-","A88806-","A88807-","G88808-","A88809-","A88810-","A88811-","T88812-","A88813-","C88814-","A88815-","T88816-","A88817-","T88818-","C88819-","G88820-","C88821-","A88822-","T88823-","A88824-","T88825-","T88826-","A88827-","T88828-","A88829-","C88830-","T88831-","T88832-","T88833-","T88834-","T88835-","T88836-","T88837-","T88838-","G88839-","G88840-","A88841-","A88842-","A88843-","T88844-","T88845-","G88846-","G88847-","A88848-","A88849-","T88850-","A88851-","C88852-","C88853-","G88854-","A88855-","T88856-","G88857-","T88858-","G88859-","T88860-","C88861-","T88862-","A88863-","C88864-","A88865-","T88866-","A88867-","A88868-","A88869-","T88870-","A88871-","C88872-","G88873-","C88874-","A88875-","A88876-","A88877-","G88878-","T88879-","C88880-","T88881-","A88882-","A88883-","A88884-","T88885-","A88886-","T88887-","T88888-","T88889-","T88890-","T88891-","T88892-","A88893-","G88894-","A88895-","G88896-","A88897-","A88898-","T88899-","C88900-","T88901-","T88902-","A88903-","G88904-","T88905-","T88906-","G88907-","G88908-","T88909-","C88910-","C88911-","A88912-","A88913-","A88914-","T88915-","T88916-","C88917-","T88918-","T88919-","T88920-","T88921-","C88922-","C88923-","A88924-","A88925-","G88926-","T88927-","A88928-","C88929-","G88930-","G88931-","T88932-","A88933-","A88934-","T88935-","A88936-","G88937-","A88938-","T88939-","T88940-","T88941-","T88942-","T88943-","C88944-","A88945-","T88946-","A88947-","T88948-","T88949-","G88950-","A88951-","A88952-","C88953-","G88954-","G88955-","T88956-","A88957-","T88958-","C88959-","T88960-","T88961-","C88962-","T88963-","T88964-","G88965-","A88966-","T88967-","C88968-","T88969-","C88970-","T88971-","G88972-","G88973-","T88974-","T88975-","C88976-","T88977-","A88978-","A88979-","T88980-","T88981-","C88982-","C88983-","G88984-","C88985-","A88986-","T88987-","T88988-","A88989-","A88990-","A88991-","T88992-","G88993-","A88994-","T88995-","G88996-","A88997-","A88998-","A88999-","C89000-","T89001-","A89002-","A89003-","G89004-","T89005-","C89006-","A89007-","C89008-","T89009-","A89010-","T89011-","T89012-","T89013-","T89014-","T89015-","A89016-","T89017-","A89018-","A89019-","C89020-","T89021-","A89022-","A89023-","C89024-","G89025-","A89026-","T89027-","T89028-","A89029-","C89030-","A89031-","T89032-","C89033-","A89034-","C89035-","C89036-","T89037-","C89038-","T89039-","A89040-","A89041-","C89042-","A89043-","T89044-","C89045-","A89046-","T89047-","C89048-","A89049-","T89050-","T89051-","T89052-","A89053-","C89054-","C89055-","A89056-","G89057-","G89058-","A89059-","T89060-","A89061-","C89062-","T89063-","G89064-","A89065-","T89066-","C89067-","T89068-","T89069-","C89070-","T89071-","T89072-","T89073-","T89074-","G89075-","T89076-","C89077-","G89078-","T89079-","A89080-","A89081-","A89082-","T89083-","A89084-","C89085-","A89086-","T89087-","G89088-","T89089-","C89090-","T89091-","A89092-","A89093-","T89094-","G89095-","T89096-","G89097-","T89098-","T89099-","A89100-","A89101-","A89102-","A89106-","A89107-","G89108-","A89109-","T89110-","C89111-","A89112-","T89113-","A89114-","C89115-","A89116-","A89117-","G89118-","T89119-","T89120-","A89121-","T89122-","A89123-","C89124-","G89125-","T89126-","C89127-","A89128-","T89129-","T89130-","T89131-","C89132-","A89133-","T89134-","C89135-","T89136-","G89137-","T89138-","A89139-","G89140-","T89141-","A89142-","T89143-","T89144-","C89145-","T89146-","T89147-","T89152-","T89153-","G89154-","A89155-","A89156-","G89157-","G89158-","A89159-","T89160-","A89161-","A89162-","A89163-","C89164-","T89165-","G89167-","T89168-","A89169-","C89170-","T89171-","A89172-","A89173-","T89174-","C89175-","T89176-","C89177-","T89178-","T89179-","C89180-","T89181-","T89182-","T89183-","A89184-","A89185-","C89186-","A89187-","G89188-","T89189-","C89190-","T89191-","G89192-","T89193-","T89194-","C89195-","A89196-","A89197-","A89198-","T89199-","T89200-","T89201-","A89202-","T89203-","A89204-","T89205-","C89206-","C89207-","T89208-","A89209-","T89210-","A89211-","T89212-","A89213-","T89214-","G89215-","A89216-","A89217-","A89218-","A89219-","A89220-","A89221-","T89222-","A89223-","G89224-","C89225-","A89226-","A89227-","C89228-","T89236-","G89237-","A89238-","T89239-","C89240-","A89241-","T89242-","C89243-","C89244-","G89245-","C89246-","G89247-","T89248-","C89249-","A89250-","A89251-","T89252-","A89253-","T89254-","T89255-","C89256-","T89257-","G89258-","T89259-","T89260-","C89261-","T89262-","A89263-","T89264-","C89265-","G89266-","T89267-","A89268-","G89269-","T89270-","G89271-","T89272-","A89273-","T89274-","A89275-","A89276-","C89277-","A89278-","A89279-","T89280-","C89281-","T89282-","T89283-","A89284-","T89285-","A89286-","T89287-","C89288-","T89289-","T89290-","C89291-","T89292-","T89293-","C89294-","T89295-","G89296-","T89297-","G89298-","A89299-","T89300-","A89301-","G89302-","T89303-","C89304-","G89305-","A89306-","T89307-","A89308-","C89309-","G89310-","T89311-","T89312-","A89313-","T89314-","A89315-","A89316-","A89317-","G89318-","G89319-","T89320-","T89321-","G89322-","A89323-","T89324-","A89325-","A89326-","C89327-","G89328-","A89329-","A89330-","A89331-","A89332-","T89333-","A89334-","T89335-","T89336-","T89337-","T89338-","T89339-","A89340-","T89341-","T89342-","T89343-","C89344-","G89345-","T89346-","G89347-","A89348-","A89349-","A89350-","T89351-","A89352-","A89353-","A89354-","G89355-","T89356-","C89357-","A89358-","T89359-","T89360-","G89361-","T89362-","A89363-","G89364-","G89365-","A89366-","T89367-","T89368-","T89369-","T89370-","G89371-","G89372-","T89395-","A89396-","T89397-","G89398-","A89399-","T89400-","T89401-","T89402-","T89403-","A89404-","T89405-","T89406-","T89407-","T89408-","T89409-","G89410-","G89411-","A89412-","A89413-","T89414-","G89415-","A89416-","T89417-","C89418-","T89419-","C89420-","A89421-","A89422-","T89423-","T89424-","A89425-","A89426-","A89427-","A89428-","T89429-","A89430-","G89431-","T89432-","C89433-","T89434-","C89435-","T89436-","T89437-","T89438-","A89439-","G89440-","A89441-","G89442-","T89443-","C89444-","C89445-","A89446-","T89447-","T89448-","T89449-","A89450-","A89451-","A89452-","G89453-","T89454-","T89455-","A89456-","C89457-","A89458-","A89459-","A89460-","C89461-","A89462-","A89463-","C89464-","T89465-","A89466-","G89467-","G89468-","A89469-","A89470-","A89471-","T89472-","T89473-","G89474-","G89475-","T89476-","T89477-","T89478-","A89479-","T89480-","G89481-","A89482-","T89483-","G89484-","T89485-","A89486-","T89487-","A89488-","A89489-","T89490-","T89491-","T89492-","T89493-","T89494-","T89495-","T89496-","A89497-","G89498-","T89499-","T89500-","T89501-","T89502-","T89503-","A89504-","T89505-","A89506-","G89507-","A89508-","T89509-","T89510-","C89511-","T89512-","T89513-","T89514-","A89515-","T89516-","T89517-","C89518-","T89519-","A89520-","T89521-","A89522-","C89523-","T89524-","T89525-","A89526-","A89527-","A89528-","A89529-","A89530-","A89531-","T89532-","G89533-","A89534-","A89535-","A89536-","A89537-","T89538-","A89539-","A89540-","A89541-","T89542-","A89543-","C89544-","A89545-","A89546-","A89547-","G89548-","G89549-","T89550-","T89551-","C89552-","T89553-","T89554-","G89555-","A89556-","G89557-","G89558-","G89559-","T89560-","T89561-","G89562-","T89563-","G89564-","T89565-","T89566-","A89567-","A89568-","T89569-","T89570-","G89571-","A89572-","A89573-","A89574-","G89575-","C89576-","G89577-","A89578-","T89579-","A89580-","A89581-","A89582-","T89583-","A89584-","A89585-","T89586-","C89587-","A89588-","T89589-","A89590-","A89591-","A89592-","T89593-","T89594-","A89595-","T89596-","T89597-","T89598-","C89599-","A89600-","T89601-","T89602-","A89603-","T89604-","C89605-","G89606-","C89607-","G89608-","A89609-","T89610-","A89611-","T89612-","C89613-","C89614-","G89615-","T89616-","T89617-","A89618-","A89619-","G89620-","T89621-","T89622-","T89623-","G89624-","T89625-","A89626-","T89627-","C89628-","G89629-","T89630-","A89631-","A89632-","T89633-","G89634-","G89635-","C89636-","G89637-","T89638-","G89639-","G89640-","T89641-","C89642-","A89643-","A89644-","T89645-","T89646-","A89647-","C89648-","G89649-","A89650-","A89651-","T89652-","A89653-","A89654-","A89655-","G89656-","C89657-","G89658-","G89659-","A89660-","T89661-","A89662-","C89663-","T89664-","A89665-","G89666-","T89667-","A89668-","G89669-","T89670-","T89671-","T89672-","C89673-","A89674-","C89675-","A89676-","A89677-","A89678-","G89679-","A89680-","T89681-","G89682-","G89683-","C89684-","T89685-","G89686-","A89687-","A89688-","A89689-","T89690-","C89691-","A89692-","G89693-","A89694-","G89695-","C89696-","T89697-","C89698-","A89699-","C89701-","T89702-","A89703-","A89704-","G89705-","A89706-","A89707-","A89708-","T89709-","A89710-","G89711-","C89712-","G89713-","C89714-","T89715-","G89716-","A89717-","A89718-","A89719-","A89720-","T89721-","A89722-","A89723-","A89724-","G89725-","A89726-","T89727-","A89728-","A89729-","A89730-","A89731-","A89732-","C89733-","G89734-","A89735-","G89736-","G89737-","A89738-","T89739-","A89740-","T89741-","T89742-","T89743-","T89744-","C89745-","C89746-","C89747-","G89748-","G89749-","A89750-","A89751-","G89752-","A89753-","T89754-","G89755-","T89756-","A89757-","A89758-","T89759-","A89760-","A89761-","T89762-","T89763-","C89764-","C89765-","A89766-","T89767-","C89768-","T89769-","A89770-","C89771-","T89772-","A89773-","A89774-","G89775-","C89776-","C89777-","C89778-","A89779-","A89780-","A89781-","A89782-","C89783-","C89784-","A89785-","A89786-","A89787-","C89788-","G89789-","A89790-","A89791-","C89792-","C89793-","A89794-","C89795-","T89796-","A89797-","C89798-","T89799-","C89800-","C89801-","T89802-","C89803-","G89804-","T89805-","A89806-","A89807-","A89808-","C89809-","C89810-","A89811-","G89812-","C89813-","G89814-","G89815-","C89816-","T89817-","A89818-","C89819-","T89820-","A89821-","A89822-","A89823-","A89824-","G89825-","A89826-","T89827-","C89828-","A89829-","A89830-","C89831-","C89832-","A89833-","A89834-","A89835-","A89836-","A89837-","G89838-","G89839-","A89840-","T89841-","A89842-","A89843-","A89844-","G89845-","A89846-","A89847-","A89848-","A89849-","G89850-","G89851-","A89852-","G89853-","G89854-","A89855-","A89856-","G89857-","T89858-","G89859-","G89860-","A89861-","A89862-","G89863-","A89864-","A89865-","G89866-","T89867-","A89868-","G89869-","T89870-","T89871-","A89872-","T89873-","A89874-","G89875-","A89876-","G89877-","G89878-","A89879-","A89880-","T89881-","A89882-","T89883-","C89884-","A89885-","T89886-","C89887-","A89888-","A89889-","A89890-","C89891-","A89892-","A89893-","C89894-","T89895-","G89896-","A89897-","A89898-","G89899-","A89900-","A89901-","A89902-","A89903-","T89904-","T89905-","C89906-","T89907-","C89908-","C89909-","A89910-","C89911-","C89912-","T89913-","C89914-","C89915-","G89916-","T89917-","C89918-","A89919-","T89920-","C89921-","A89922-","T89923-","C89924-","T89925-","C89926-","C89927-","T89928-","G89929-","G89930-","A89931-","G89932-","T89933-","C89934-","G89935-","G89936-","C89937-","G89938-","A89939-","C89940-","A89941-","T89942-","T89943-","G89944-","T89945-","A89946-","G89947-","A89948-","A89949-","A89950-","G89951-","C89952-","G89953-","T89954-","G89955-","G89956-","C89957-","C89958-","G89959-","C89960-","T89961-","G89962-","T89963-","A89964-","G89965-","A89966-","G89967-","C89968-","T89969-","C89970-","G89971-","A89972-","T89973-","G89974-","A89975-","T89976-","A89977-","G89978-","C89979-","G89980-","A89981-","C89982-","G89983-","G89984-","G89985-","G89986-","A89987-","T89988-","G89989-","A89990-","T89991-","G89992-","A89993-","A89994-","C89995-","C89996-","T89997-","A89998-","T89999-","G90000-","G90001-","T90002-","A90003-","C90004-","A90005-","A90006-","G90007-","T90008-","T90009-","G90010-","A90011-","A90012-","G90013-","C90014-","T90015-","G90016-","G90017-","T90018-","A90019-","A90020-","A90021-","G90022-","T90023-","A90024-","A90025-","A90026-","T90027-","C90028-","A90029-","T90030-","A90031-","G90032-","T90033-","G90034-","C90035-","T90036-","A90037-","G90038-","A90039-","A90040-","G90041-","C90042-","G90043-","A90044-","T90045-","C90046-","T90047-","C90048-","T90049-","C90050-","T90051-","G90052-","A90053-","C90054-","C90055-","T90056-","A90057-","A90058-","A90059-","G90060-","G90061-","T90062-","G90063-","G90064-","C90065-","T90066-","A90067-","C90068-","C90069-","G90070-","A90071-","C90072-","A90073-","A90074-","T90075-","A90076-","T90077-","C90078-","G90079-","T90080-","T90081-","A90082-","A90083-","A90084-","G90085-","A90086-","T90087-","C90088-","T90089-","T90090-","A90091-","A90092-","G90093-","A90094-","A90095-","A90096-","A90097-","T90098-","T90099-","A90100-","T90101-","T90102-","A90103-","C90104-","T90105-","A90106-","G90107-","A90108-","A90109-","T90110-","C90111-","T90112-","C90113-","T90114-","G90115-","C90116-","A90117-","G90118-","T90119-","A90120-","T90121-","C90122-","G90123-","A90124-","C90125-","T90126-","G90127-","T90128-","T90129-","C90130-","T90131-","A90132-","G90133-","A90134-","G90135-","G90136-","A90137-","T90138-","G90139-","T90140-","T90141-","C90142-","A90143-","A90144-","G90145-","C90146-","A90147-","G90148-","C90149-","T90150-","G90151-","G90152-","T90153-","A90154-","T90155-","C90156-","T90157-","C90158-","T90159-","A90160-","G90161-","A90162-","C90163-","A90164-","A90165-","T90166-","T90167-","T90168-","A90169-","C90170-","T90171-","T90172-","C90173-","T90174-","A90175-","T90176-","G90177-","A90178-","C90179-","T90180-","A90181-","A90182-","A90183-","G90184-","C90185-","T90186-","A90187-","T90188-","T90189-","A90190-","C90191-","A90192-","A90193-","C90194-","A90195-","C90196-","T90197-","A90198-","T90199-","C90200-","T90201-","G90202-","A90203-","T90204-","C90205-","T90206-","A90207-","G90208-","T90209-","C90210-","A90211-","C90212-","C90213-","G90214-","A90215-","G90216-","G90217-","G90218-","A90219-","A90220-","A90221-","A90222-","T90223-","C90224-","T90225-","A90226-","A90227-","A90228-","G90229-","T90230-","T90231-","G90232-","T90233-","T90234-","C90235-","G90236-","T90237-","A90238-","A90239-","A90240-","A90241-","A90242-","A90243-","G90244-","T90245-","T90246-","A90247-","A90248-","A90249-","A90250-","C90251-","T90252-","T90253-","G90254-","T90255-","A90256-","A90257-","G90258-","A90259-","A90260-","G90261-","T90262-","A90263-","A90264-","A90265-","T90266-","G90267-","C90268-","G90269-","T90270-","G90271-","C90272-","A90273-","C90274-","T90275-","T90276-","T90277-","T90278-","T90279-","T90280-","A90281-","T90282-","A90283-","A90284-","A90285-","G90286-","A90287-","T90288-","G90289-","G90290-","T90291-","A90292-","A90293-","A90294-","C90295-","T90296-","G90297-","T90298-","T90299-","T90300-","A90301-","C90302-","C90303-","G90304-","A90305-","T90306-","A90307-","A90308-","T90309-","A90310-","A90311-","T90312-","T90313-","T90314-","T90315-","T90316-","T90317-","A90318-","A90319-","A90320-","T90321-","C90322-","C90323-","T90324-","G90325-","T90326-","A90327-","T90328-","C90329-","A90330-","G90331-","A90332-","C90333-","G90334-","A90335-","T90336-","A90337-","A90338-","T90339-","C90340-","C90341-","A90342-","G90343-","C90344-","G90345-","T90346-","A90347-","T90348-","G90349-","A90350-","G90351-","G90352-","T90353-","T90354-","T90355-","T90356-","G90357-","C90358-","A90359-","A90360-","C90361-","A90362-","T90363-","G90364-","T90365-","T90366-","A90367-","A90368-","A90369-","A90370-","T90371-","T90372-","C90373-","C90374-","T90375-","A90376-","C90377-","T90378-","C90379-","A90380-","T90381-","T90382-","T90383-","A90384-","A90385-","C90386-","A90387-","G90388-","A90389-","T90390-","G90391-","T90392-","A90393-","G90394-","T90395-","A90396-","G90397-","T90398-","A90399-","T90400-","A90401-","T90402-","G90403-","A90404-","A90405-","C90406-","A90407-","A90408-","A90409-","C90410-","G90411-","T90412-","G90413-","G90414-","G90415-","A90416-","A90417-","G90418-","A90419-","G90420-","G90421-","C90422-","A90423-","T90424-","T90425-","A90426-","A90427-","C90428-","T90429-","A90430-","G90431-","A90432-","T90433-","T90434-","A90435-","A90436-","T90437-","T90438-","T90439-","T90440-","T90441-","G90442-","T90443-","G90444-","G90445-","G90446-","A90447-","A90448-","G90449-","T90450-","G90451-","A90452-","T90453-","T90454-","C90455-","A90456-","A90457-","A90458-","A90459-","G90460-","G90461-","A90462-","C90463-","G90464-","T90465-","A90466-","G90467-","A90468-","C90469-","A90470-","A90471-","T90472-","A90473-","C90474-","T90475-","T90476-","T90477-","T90478-","A90479-","C90480-","G90481-","G90482-","A90483-","A90484-","A90485-","A90486-","A90487-","T90488-","G90489-","C90490-","A90491-","T90492-","A90493-","T90494-","A90495-","C90496-","A90497-","G90498-","A90499-","A90500-","T90501-","C90502-","G90503-","C90504-","A90505-","A90506-","T90507-","G90508-","C90509-","T90510-","A90511-","A90512-","A90513-","A90514-","G90515-","A90516-","G90517-","A90518-","T90519-","C90520-","G90521-","T90522-","A90523-","T90524-","T90525-","T90526-","T90527-","T90528-","G90529-","T90530-","T90531-","A90532-","G90533-","A90534-","G90535-","T90536-","A90537-","T90538-","A90539-","T90540-","A90541-","A90542-","C90543-","G90544-","T90545-","T90546-","A90547-","T90548-","G90549-","A90550-","A90551-","A90552-","C90553-","G90554-","A90555-","A90556-","T90557-","T90558-","A90559-","A90560-","T90561-","T90562-","G90563-","T90564-","T90565-","T90566-","T90567-","A90568-","T90569-","A90570-","A90571-","A90572-","C90573-","A90574-","A90575-","A90576-","A90577-","A90578-","T90579-","A90580-","T90581-","A90582-","A90583-","A90584-","G90585-","A90586-","A90587-","A90588-","T90589-","C90590-","G90591-","T172130-","T172131-","C172132-","C172133-","T173843-","A173844-","G173845-","T173846-","A173847-"],"OPG080":["S84-","N85-"]},"labels":{"aa":"OPG080: S84-, N85-"}}}]}]}]}]},{"name":"NODE_0000132","node_attrs":{"div":1,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C182950T"],"OPG210":["S532L"]},"labels":{"aa":"OPG210: S532L","clade":"B.1.12"}},"children":[{"name":"NODE_0000133","node_attrs":{"div":3,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G1302A","C57550T","G78328A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C195908T"],"OPG001":["L92F"],"OPG001_dup":["L92F"]},"labels":{"aa":"OPG001: L92F; OPG001_dup: L92F"}},"children":[{"name":"OP415207","node_attrs":{"div":3,"accession":"OP415207","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_BhVKjm_9000233"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415207/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OP415206","node_attrs":{"div":3,"accession":"OP415206","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_BhVKjm_9000232"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415206/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000134","node_attrs":{"div":2,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G111084A"]}},"children":[{"name":"ON880548","node_attrs":{"div":2,"accession":"ON880548","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3448/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880548/2022-06-03"},"date":{"value":"2022-06-03"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000135","node_attrs":{"div":4,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G98233A","G98455A","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG117":["D729N"],"OPG118":["G4K"]},"labels":{"aa":"OPG117: D729N; OPG118: G4K"}},"children":[{"name":"ON880413","node_attrs":{"div":5,"accession":"ON880413","author":{"author":"Coletti,T.M.,Ghilardi,F.,khan,M.J.,Claro,I.M.,Valenca,I.N.,Faria,N.R.,Sabino,E.C.","value":"Coletti,T.M.,Ghilardi,F.,khan,M.J.,Claro,I.M.,Valenca,I.N.,Faria,N.R.,Sabino,E.C."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/BR0002/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Imperial College London, School of Public Health"},"strain_display":{"value":"Brazil/ON880413/2022-06-14"},"date":{"value":"2022-06-14"},"country":{"value":"Brazil"}},"branch_attrs":{"mutations":{"nuc":["C76334T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A173314-","T173315-","A173316-","T173317-","-179189A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG097":["R181K"]},"labels":{"aa":"OPG097: R181K"}}},{"name":"NODE_0000136","node_attrs":{"div":5,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G98456A"]}},"children":[{"name":"OP270022","node_attrs":{"div":8,"accession":"OP270022","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3972/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP270022/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","G3361A","C152970T","-179158A","-179160A","-179161T","-179162A","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G181349A","C193849T"],"OPG003":["S416L"],"OPG003_dup":["S416L"]},"labels":{"aa":"OPG003: S416L; OPG003_dup: S416L"}}},{"name":"OP378701","node_attrs":{"div":6,"accession":"OP378701","author":{"author":"Gigante,C.M.,Hughes,S.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_NY0028"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP378701/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T4775-","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","C40966T","C179154-","A179155-","T179156-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"],"OPG060":["D73N"]},"labels":{"aa":"OPG060: D73N"}}},{"name":"OR209309","node_attrs":{"div":8,"accession":"OR209309","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_TN0019"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OR209309/2022-12-XX"},"date":{"value":"2022-12-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C93601T","C94418T","T133101-","T133102-","C136029T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["A624V"],"OPG114":["E84K"]},"labels":{"aa":"OPG113: A624V; OPG114: E84K"}}},{"name":"NODE_0000137","node_attrs":{"div":6,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C24231T"]}},"children":[{"name":"OP390179","node_attrs":{"div":6,"accession":"OP390179","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"BOL-UNIMOL-MPX-293015-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"strain_display":{"value":"Colombia/OP390179/2022-08-24"},"date":{"value":"2022-08-24"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OR264365","node_attrs":{"div":7,"accession":"OR264365","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"12_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264365/2022-07-18"},"date":{"value":"2022-07-18"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["G23457A"],"OPG039":["S221F"]},"labels":{"aa":"OPG039: S221F"}}}]},{"name":"NODE_0000138","node_attrs":{"div":6,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G153910A"],"OPG180":["E407K"]},"labels":{"aa":"OPG180: E407K"}},"children":[{"name":"OQ918701","node_attrs":{"div":11,"accession":"OQ918701","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00490/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ918701/2023-02-10"},"date":{"value":"2023-02-10"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C21910T","G28483A","G39552A","A57421-","C57422-","A57423-","A57424-","A57425-","A57426-","A57427-","G57428-","G57429-","A57430-","C57431-","A57432-","T57433-","G57434-","T57435-","A57436-","A57437-","A57438-","C57439-","T57440-","T57441-","G132490A","C150443T","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG037":["R175K"],"OPG057":["S215F"],"OPG075":["K20-","F21-","T22-","C23-","P24-","F25-","C26-"],"OPG176":["T212I"]},"labels":{"aa":"OPG037: R175K; OPG057: S215F; OPG075: K20-, F21-, T22-, C23-, P24-, F25-, C26-; OPG176: T212I"}}},{"name":"OR759180","node_attrs":{"div":10,"accession":"OR759180","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL092/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759180/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["T606-","C16209T","C24208T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","G182088A","G182189A","A196614-"],"OPG027":["E57K"],"OPG210":["E245K"]},"labels":{"aa":"OPG027: E57K; OPG210: E245K"}}}]}]}]}]}]},{"name":"NODE_0000139","node_attrs":{"div":2,"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G12169A","G44960A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]},"labels":{"clade":"B.1.17"}},"children":[{"name":"OP442552","node_attrs":{"div":2,"accession":"OP442552","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00085/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP442552/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G771-","T772-","G773-","A196789-","A196790-","T196791-"]}}},{"name":"OP890564","node_attrs":{"div":3,"accession":"OP890564","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00336/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP890564/2022-11-09"},"date":{"value":"2022-11-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A39482T"],"OPG057":["H238Q"]},"labels":{"aa":"OPG057: H238Q"}}},{"name":"OP890557","node_attrs":{"div":3,"accession":"OP890557","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00329/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP890557/2022-11-09"},"date":{"value":"2022-11-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","A13238C","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000140","node_attrs":{"div":3,"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A39081T","A196780-","A196781-","T196782-"],"OPG057":["I372N"]},"labels":{"aa":"OPG057: I372N"}},"children":[{"name":"OP890570","node_attrs":{"div":4,"accession":"OP890570","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00313/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP890570/2022-11-09"},"date":{"value":"2022-11-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G178111A","C196672-","T196673-","G196674-"]}}},{"name":"OP890553","node_attrs":{"div":3,"accession":"OP890553","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00325/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP890553/2022-11-09"},"date":{"value":"2022-11-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000141","node_attrs":{"div":3,"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G140635A"],"OPG160":["S147L"]},"labels":{"aa":"OPG160: S147L"}},"children":[{"name":"OP890567","node_attrs":{"div":5,"accession":"OP890567","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00310/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP890567/2022-11-09"},"date":{"value":"2022-11-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C39334G","G164476A"],"OPG057":["A288P"],"OPG189":["E382K"]},"labels":{"aa":"OPG057: A288P; OPG189: E382K"}}},{"name":"OP890569","node_attrs":{"div":4,"accession":"OP890569","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00312/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP890569/2022-11-09"},"date":{"value":"2022-11-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A763-","A764-","T765-","G39312T","-179145T","T179244-","T196678-","C196679-","T196680-"],"OPG057":["A295E"]},"labels":{"aa":"OPG057: A295E"}}}]},{"name":"NODE_0000142","node_attrs":{"div":3,"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A39395-","T39396-","T39397-","C85931T"],"OPG057":["N267-"]},"labels":{"aa":"OPG057: N267-"}},"children":[{"name":"OQ330999","node_attrs":{"div":4,"accession":"OQ330999","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00391/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ330999/2022-12-19"},"date":{"value":"2022-12-19"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C174129T"]}}},{"name":"OQ503816","node_attrs":{"div":3,"accession":"OQ503816","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00423/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ503816/2022-12-02"},"date":{"value":"2022-12-02"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000143","node_attrs":{"div":5,"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G71249A","G182189A"],"OPG090":["R24Q"]},"labels":{"aa":"OPG090: R24Q"}},"children":[{"name":"OQ547884","node_attrs":{"div":6,"accession":"OQ547884","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000176/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDPH, VRDL"},"strain_display":{"value":"USA/OQ547884/2023-01-06"},"date":{"value":"2023-01-06"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T760-","T761-","T762-","G79741A"],"OPG102":["M219I"]},"labels":{"aa":"OPG102: M219I"}}},{"name":"OQ644784","node_attrs":{"div":7,"accession":"OQ644784","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00478/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ644784/2023-01-08"},"date":{"value":"2023-01-08"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A11160G","T133529G"],"OPG023":["F581L"]},"labels":{"aa":"OPG023: F581L"}}}]}]}]},{"name":"NODE_0000144","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C132698T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}},"children":[{"name":"OP555508","node_attrs":{"div":4,"accession":"OP555508","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0416/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555508/2022-07-26"},"date":{"value":"2022-07-26"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G40375A","C92352T","C120425T"],"OPG137":["S275L"]},"labels":{"aa":"OPG137: S275L"}}},{"name":"OP555512","node_attrs":{"div":1,"accession":"OP555512","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0424/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555512/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-607T"]}}},{"name":"OP555662","node_attrs":{"div":3,"accession":"OP555662","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0595/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555662/2022-09-16"},"date":{"value":"2022-09-16"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T109045C","T122837G"],"OPG128":["Y4C"],"OPG143":["N160T"]},"labels":{"aa":"OPG128: Y4C; OPG143: N160T"}}},{"name":"NODE_0000145","node_attrs":{"div":7,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C18441T","G22415A","G70002A","G143951A","C148604T","G154188A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C196745-","C196746-","A196747-"],"OPG031":["E130K"],"OPG089":["R46K"],"OPG165":["D146N"],"OPG174":["M264I"]},"labels":{"aa":"OPG031: E130K; OPG089: R46K; OPG165: D146N; OPG174: M264I"}},"children":[{"name":"OR643700","node_attrs":{"div":10,"accession":"OR643700","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00558/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643700/2023-08-24"},"date":{"value":"2023-08-24"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C96773T","A166129G","G168741A"],"OPG117":["S242L"],"OPG195":["R171K"]},"labels":{"aa":"OPG117: S242L; OPG195: R171K"}}},{"name":"OR499996","node_attrs":{"div":9,"accession":"OR499996","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00540/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499996/2023-07-01"},"date":{"value":"2023-07-01"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G30433A","C57102T","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR499994","node_attrs":{"div":7,"accession":"OR499994","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00538/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499994/2023-07-21"},"date":{"value":"2023-07-21"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499993","node_attrs":{"div":7,"accession":"OR499993","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00537/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499993/2023-07-06"},"date":{"value":"2023-07-06"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000146","node_attrs":{"div":9,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G70425A","C137966T"],"OPG089":["G187E"],"OPG154":["E29K"]},"labels":{"aa":"OPG089: G187E; OPG154: E29K"}},"children":[{"name":"OR643711","node_attrs":{"div":9,"accession":"OR643711","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00555/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643711/2023-08-02"},"date":{"value":"2023-08-02"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR643708","node_attrs":{"div":9,"accession":"OR643708","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00553/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643708/2023-07-28"},"date":{"value":"2023-07-28"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000147","node_attrs":{"div":8,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C14823A"],"OPG025":["D149Y"]},"labels":{"aa":"OPG025: D149Y"}},"children":[{"name":"OR643701","node_attrs":{"div":8,"accession":"OR643701","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00559/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643701/2023-08-07"},"date":{"value":"2023-08-07"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499982","node_attrs":{"div":8,"accession":"OR499982","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00525/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499982/2023-06-14"},"date":{"value":"2023-06-14"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000148","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C148268T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"ON755039","node_attrs":{"div":1,"accession":"ON755039","author":{"author":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O.","value":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_IRBA22-11"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IRBA, D.DNRBC/D.2MI/U.BACT"},"strain_display":{"value":"France/ON755039/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OR035703","node_attrs":{"div":2,"accession":"OR035703","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_97"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035703/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C162521T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T"],"OPG188":["S309L"]},"labels":{"aa":"OPG188: S309L"}}},{"name":"OR264451","node_attrs":{"div":4,"accession":"OR264451","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"65_D"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264451/2022-08-25"},"date":{"value":"2022-08-25"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["T96531G","G158414A","G159694A","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG185":["V260I"]},"labels":{"aa":"OPG185: V260I"}}},{"name":"NODE_0000149","node_attrs":{"div":2,"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G9963A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T"],"OPG021":["R126K"]},"labels":{"aa":"OPG021: R126K","clade":"B.1.19"}},"children":[{"name":"OP270026","node_attrs":{"div":2,"accession":"OP270026","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-4017/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP270026/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-196615A","-196616A","-196617A"]}}},{"name":"OP382481","node_attrs":{"div":4,"accession":"OP382481","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00004"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382481/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["G115549A","T133102-","C163653T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"],"OPG133":["P50S"]},"labels":{"aa":"OPG133: P50S"}}},{"name":"OP838893","node_attrs":{"div":2,"accession":"OP838893","author":{"author":"Viscardi,M.,Cozzolino,L.,De Martinis,C.,Cardillo,L.,Fusco,G.","value":"Viscardi,M.,Cozzolino,L.,De Martinis,C.,Cardillo,L.,Fusco,G."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ID6821"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Istituto Zooprofilattico Sperimentale del Mezzogiorno, Hanimal Health"},"strain_display":{"value":"Italy/OP838893/2022-06-21"},"date":{"value":"2022-06-21"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","T133100-","T133101-","T133102-","C133103-","G133104-","A133105-","A133106-","T133107-","T133108-","C133109-","A133110-","C133111-","G133112-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A157678-","A157679-","A157680-","A157681-","T157682-","T157683-","T157684-","T157685-","A157686-","A157687-","G157688-","C157689-","G157690-","A157691-","T157692-","G157693-","A157694-","T157695-","A157696-","T163214-","C163215-","T163216-","T163217-","A163218-","T163219-","A163220-","T163221-","A163417-","A163418-","T163419-","T163420-","C163421-","T163422-","T163423-","C163424-","C163425-","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","G174537-","A174538-","T174539-","G174540-","A174541-","A174542-","A180482-","T180483-","T180484-","A180485-","A180486-","A180487-","A180488-","A180489-","A181114-","T181115-","T181116-","C181117-","C181118-","T181119-","T181120-","A181121-","T181122-","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-"],"OPG159":["N124-","Y125-","N126-"],"OPG189":["N29-","S30-","S31-"]},"labels":{"aa":"OPG159: N124-, Y125-, N126-; OPG189: N29-, S30-, S31-"}}},{"name":"OR035726","node_attrs":{"div":4,"accession":"OR035726","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_120"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035726/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C22739T","G133104A","G133231A","T137560-","G164487A"],"OPG038":["E141K"]},"labels":{"aa":"OPG038: E141K"}}},{"name":"NODE_0000150","node_attrs":{"div":3,"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G150003A"]}},"children":[{"name":"OP382486","node_attrs":{"div":6,"accession":"OP382486","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00009"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382486/2022-07-07"},"date":{"value":"2022-07-07"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["C38483T","C164272T","G175971A","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"],"OPG189":["R314C"],"OPG205":["E106K"]},"labels":{"aa":"OPG189: R314C; OPG205: E106K"}}},{"name":"OP555643","node_attrs":{"div":6,"accession":"OP555643","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0572/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555643/2022-09-05"},"date":{"value":"2022-09-05"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-607T","C55057T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A169944T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C185326T","-196615A"],"OPG073":["E29K"],"OPG197":["E92V"],"OPG210":["S1324L"]},"labels":{"aa":"OPG073: E29K; OPG197: E92V; OPG210: S1324L"}}},{"name":"OQ172215","node_attrs":{"div":7,"accession":"OQ172215","author":{"author":"Zeggagh,J.,Ferraris,O.,Salmona,M.,Tarantola,A.,Molina,J.M.,Delaugerre,C.","value":"Zeggagh,J.,Ferraris,O.,Salmona,M.,Tarantola,A.,Molina,J.M.,Delaugerre,C."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-1047"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Hopital Saint Louis, Paris"},"strain_display":{"value":"France/OQ172215/2022-06-07"},"date":{"value":"2022-06-07"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["A2591G","A31053G","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133171-","C133172-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T133639-","A150635-","A152676-","T152686-","T155897A","C173533A","A179077T","A179079T","A179081T","C179082T","A179083T","A179086T","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T194619C","T194627G"],"OPG002":["F54S"],"OPG002_dup":["F54S","C57G"],"OPG047":["C48R"]},"labels":{"aa":"OPG002: F54S; OPG002_dup: F54S, C57G; OPG047: C48R"}}},{"name":"NODE_0000151","node_attrs":{"div":4,"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C74417T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"],"OPG094":["S213L"]},"labels":{"aa":"OPG094: S213L"}},"children":[{"name":"OP536781","node_attrs":{"div":5,"accession":"OP536781","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000405"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536781/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C62868T"]}}},{"name":"NODE_0000152","node_attrs":{"div":5,"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C22179T"]}},"children":[{"name":"OP536803","node_attrs":{"div":5,"accession":"OP536803","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000431"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536803/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["G190782-","A190783-","A190784-","A190785-"],"OPG016":["E125-","I126-"]},"labels":{"aa":"OPG016: E125-, I126-"}}},{"name":"OP536782","node_attrs":{"div":5,"accession":"OP536782","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000406"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536782/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-606T","-196614A"]}}}]}]}]}]}]},{"name":"NODE_0000153","node_attrs":{"div":1,"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G5595A","C191615T"],"OPG015":["Q188*"],"OPG015_dup":["Q188*"]},"labels":{"aa":"OPG015: Q188*; OPG015_dup: Q188*","clade":"B.1.8"}},"children":[{"name":"OP215224","node_attrs":{"div":1,"accession":"OP215224","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI235"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP215224/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000154","node_attrs":{"div":2,"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G902A","G161296A","C196308T"],"OPG001_dup":["S225L"]},"labels":{"aa":"OPG001_dup: S225L"}},"children":[{"name":"OP331337","node_attrs":{"div":2,"accession":"OP331337","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000183"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP331337/2022-06-29"},"date":{"value":"2022-06-29"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG001":["S225L"]},"labels":{"aa":"OPG001: S225L"}}},{"name":"OP484679","node_attrs":{"div":2,"accession":"OP484679","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI358"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP484679/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG001":["S225L"]},"labels":{"aa":"OPG001: S225L"}}},{"name":"OP626130","node_attrs":{"div":3,"accession":"OP626130","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI492"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP626130/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A902G","C24929T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T196308C"],"OPG001_dup":["L225S"],"OPG040":["D184N"]},"labels":{"aa":"OPG001_dup: L225S; OPG040: D184N"}}},{"name":"OP863250","node_attrs":{"div":5,"accession":"OP863250","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI600"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP863250/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A902G","G89716A","G128858A","-179188T","-179189A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","G181052-","C186220T"],"OPG110":["E29K"],"OPG209":["G179-"],"OPG210":["A1622V"]},"labels":{"aa":"OPG110: E29K; OPG209: G179-; OPG210: A1622V"}}},{"name":"OR035714","node_attrs":{"div":5,"accession":"OR035714","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_108"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035714/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["A902G","C80545T","G102614A","C170573T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG103":["S182L"],"OPG122":["V63I"],"OPG198":["S179L"]},"labels":{"aa":"OPG103: S182L; OPG122: V63I; OPG198: S179L"}}},{"name":"OR030928","node_attrs":{"div":3,"accession":"OR030928","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_17"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR030928/2022-07-19"},"date":{"value":"2022-07-19"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C68981T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG001":["S225L"],"OPG087":["S42L"]},"labels":{"aa":"OPG001: S225L; OPG087: S42L"}}}]},{"name":"NODE_0000155","node_attrs":{"div":3,"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G78034A","C80111T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG099":["D124N"]},"labels":{"aa":"OPG099: D124N"}},"children":[{"name":"ON720849","node_attrs":{"div":4,"accession":"ON720849","author":{"author":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/Spain/MD-HGUGM-6532064/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Microbial Genomics, Hospital General Universitario Gregorio Marañón, Madrid, Spain"},"strain_display":{"value":"Spain/ON720849/2022-05-27"},"date":{"value":"2022-05-27"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["A327-","T604-","T605-","T606-","A1697-","A8055-","A9529-","C11749-","T15127-","T16099-","A19360-","A21081-","A27114-","A28529-","A28530-","A28602-","T32194-","A33199-","T34046-","T35571-","T37982-","T39131-","T39866-","T41744-","A43500-","T43509-","T46648-","A55124-","T56040-","A57277-","A58650-","A62041-","T64752-","A64935-","G69145-","A69744-","T76084-","T76085-","A76890-","A79181-","T79229-","A79460-","A79787-","T80849-","T88095-","T88836-","A89106-","A91705-","T94647-","T94795-","A98080-","T103367-","T105360-","T108715-","A110978-","T114518-","T114755-","A116014-","T116963-","T121121-","C122649T","A123995-","A124727-","A127250-","A127754-","A128933-","A132023-","A132024-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133639-","T137886-","A138474-","A142466-","A144230-","A148000-","A148351-","T150539-","A150635-","A151986-","A152676-","T152686-","A153424-","A154129-","T155424-","A157997-","T163597-","T168120-","A168962-","A170728-","T170904-","T172087-","T172667-","T178048-","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","A179950-","G181052-","A181253-","A182646-","T187080-","A190935-","T195519-","A196593-","A196611-","A196612-","A196613-","A196614-","T197183-"],"OPG016":["T176-"],"OPG044":["K147-"],"OPG084":["F11-"],"OPG087":["G97-"],"OPG102":["K33-","K126-","K235-"],"OPG115":["S46-"],"OPG117":["K678-"],"OPG134":["N89-"],"OPG143":["D223N"],"OPG145":["M17-"],"OPG149":["K19-"],"OPG151":["N4-","K1034-"],"OPG163":["N89-"],"OPG165":["M239-"],"OPG172":["I192-"],"OPG178":["M160-"],"OPG180":["N245-"],"OPG189":["F89-"],"OPG193":["F263-"],"OPG198":["K231-"],"OPG208":["N229-"],"OPG209":["G179-"],"OPG210":["K431-"]},"labels":{"aa":"OPG016: T176-; OPG044: K147-; OPG084: F11-; OPG087: G97-; OPG102: K33-, K126-, K235-; OPG115: S46-; OPG117: K678-; OPG134: N89-; OPG143: D223N; OPG145: M17-; OPG149: K19-; OPG151: N4-, K1034-; OPG163: N89-; OPG165: M239-; OPG172: I192-; OPG178: M160-; OPG180: N245-; OPG189: F89-; OPG193: F263-; OPG198: K231-; OPG208: N229-; OPG209: G179-; OPG210: K431-"}}},{"name":"ON622718","node_attrs":{"div":4,"accession":"ON622718","author":{"author":"Martinez-Puchol,S.,Coello,A.,Bordoy,A.E.,Soler,L.,Panisello,D.,Gonzalez-Gomez,S.,Clara,G.,Paris de Leon,A.,Not,A.,Hernandez,A.,Bofill-Mas,S.,Saludes,V.,Blanco,I.,Martro,E.,Cardona,P.-J.","value":"Martinez-Puchol,S.,Coello,A.,Bordoy,A.E.,Soler,L.,Panisello,D.,Gonzalez-Gomez,S.,Clara,G.,Paris de Leon,A.,Not,A.,Hernandez,A.,Bofill-Mas,S.,Saludes,V.,Blanco,I.,Martro,E.,Cardona,P.-J."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/ES0001/HUGTiP/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Microbiology, Hospital Universitari Germans Trias i Pujol, Spain"},"strain_display":{"value":"Spain/ON622718/2022-05-20"},"date":{"value":"2022-05-20"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C14113-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T139150C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","-196615A","-196616A"],"OPG156":["Q87R"]},"labels":{"aa":"OPG156: Q87R"}}},{"name":"NODE_0000156","node_attrs":{"div":5,"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G22643A","G63811A","-179194A","-179195T","-179196A","-179197T","-179198A"],"OPG038":["H173Y"]},"labels":{"aa":"OPG038: H173Y"}},"children":[{"name":"OP303778","node_attrs":{"div":5,"accession":"OP303778","author":{"author":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_FL0015"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP303778/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP415254","node_attrs":{"div":7,"accession":"OP415254","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_imBNaw_9000300"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415254/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T119985C","A179194-","T179195-","A179196-","T179197-","A179198-","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","G189258A"]}}},{"name":"OP477454","node_attrs":{"div":5,"accession":"OP477454","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-23267-O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP477454/2022-08-23"},"date":{"value":"2022-08-23"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP477452","node_attrs":{"div":5,"accession":"OP477452","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-23265-C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP477452/2022-08-23"},"date":{"value":"2022-08-23"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP450995","node_attrs":{"div":5,"accession":"OP450995","author":{"author":"Gigante,C.M.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.M.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_TN0001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP450995/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179199C","-179200A","-179201T","-179202T","A182310-","T182311-","T182312-","G182313-","G182314-","T182315-","G182316-","T182317-","A182318-","A182319-","A182320-","A182321-","G182322-","A182323-","T182324-","G182325-","A182326-","T182327-","G182328-","A182329-","A182330-","A182331-"],"OPG210":["I319-","G320-","V321-","K322-","D323-","D324-","E325-","N326-"]},"labels":{"aa":"OPG210: I319-, G320-, V321-, K322-, D323-, D324-, E325-, N326-"}}},{"name":"OP642374","node_attrs":{"div":6,"accession":"OP642374","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-24722-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642374/2022-09-08"},"date":{"value":"2022-09-08"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G168759A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG195":["R177K"]},"labels":{"aa":"OPG195: R177K"}}},{"name":"OQ320513","node_attrs":{"div":9,"accession":"OQ320513","author":{"author":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y.","value":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_FL0009"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ320513/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G4038A","A39081T","C67289T","G73790A","T133102-","A173284-","T173285-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","C193172T"],"OPG057":["I372N"],"OPG085":["E415K"],"OPG094":["G4E"]},"labels":{"aa":"OPG057: I372N; OPG085: E415K; OPG094: G4E"}}},{"name":"OR759149","node_attrs":{"div":9,"accession":"OR759149","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL055/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759149/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C8555T","G95862A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168089T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G181674A","-196615A"],"OPG116":["A168T"],"OPG210":["E107K"]},"labels":{"aa":"OPG116: A168T; OPG210: E107K"}}}]}]}]},{"name":"NODE_0000157","node_attrs":{"div":4,"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C18133T","G67611A","G130231A","G159277A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG185":["E121K"]},"labels":{"aa":"OPG185: E121K","clade":"B.1.11"}},"children":[{"name":"OP169336","node_attrs":{"div":4,"accession":"OP169336","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-070499/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP169336/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A"]}}},{"name":"OP440582","node_attrs":{"div":5,"accession":"OP440582","author":{"author":"Hemarajata,P.,Green,N.M.","value":"Hemarajata,P.,Green,N.M."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00009/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP440582/2022-07-22"},"date":{"value":"2022-07-22"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C31162T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP390178","node_attrs":{"div":4,"accession":"OP390178","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MAG-UNIMOL-MPX-292982-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"strain_display":{"value":"Colombia/OP390178/2022-08-20"},"date":{"value":"2022-08-20"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP378706","node_attrs":{"div":5,"accession":"OP378706","author":{"author":"Gigante,C.M.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.M.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_IL0053"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP378706/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C161002T","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP536709","node_attrs":{"div":5,"accession":"OP536709","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-USA-IL-IDPH-048"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"strain_display":{"value":"USA/OP536709/2022-06-23"},"date":{"value":"2022-06-23"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","T48717A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A","-196616A","-196617A"],"OPG068":["L173I"]},"labels":{"aa":"OPG068: L173I"}}},{"name":"OP536703","node_attrs":{"div":4,"accession":"OP536703","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-USA-IL-IDPH-042"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"strain_display":{"value":"USA/OP536703/2022-06-23"},"date":{"value":"2022-06-23"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G173318A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A","-196616A","-196617A"]}}},{"name":"OP603012","node_attrs":{"div":4,"accession":"OP603012","author":{"author":"Gigante,C.M.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y.","value":"Gigante,C.M.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_CA0034"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP603012/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"]}}},{"name":"OP819960","node_attrs":{"div":7,"accession":"OP819960","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"SAN_INS_MPX_0973_L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP819960/2022-10-17"},"date":{"value":"2022-10-17"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A19748-","G19749-","G19750-","C19751-","G19752-","T19753-","G27840A","C64404T","C96810T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG034":["T87-","P88-"],"OPG043":["S39F"],"OPG083":["D105N"]},"labels":{"aa":"OPG034: T87-, P88-; OPG043: S39F; OPG083: D105N"}}},{"name":"OP642421","node_attrs":{"div":5,"accession":"OP642421","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-25510E"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642421/2022-09-03"},"date":{"value":"2022-09-03"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C90842T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG111":["S193F"]},"labels":{"aa":"OPG111: S193F"}}},{"name":"OQ148469","node_attrs":{"div":7,"accession":"OQ148469","author":{"author":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LBMB-UTP_MP-013_VAC"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"strain_display":{"value":"Colombia/OQ148469/2022-11-11"},"date":{"value":"2022-11-11"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C29040T","G128544A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","G182189A"],"OPG045":["D75N"],"OPG150":["D256N"]},"labels":{"aa":"OPG045: D75N; OPG150: D256N"}}},{"name":"OP959063","node_attrs":{"div":6,"accession":"OP959063","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"BOL-UNIMOL-MPX-293633-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"strain_display":{"value":"Colombia/OP959063/2022-11-15"},"date":{"value":"2022-11-15"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C132590T","G139081A"],"OPG156":["S110F"]},"labels":{"aa":"OPG156: S110F"}}},{"name":"OP959062","node_attrs":{"div":4,"accession":"OP959062","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"BOL-UNIMOL-MPX-293614-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"strain_display":{"value":"Colombia/OP959062/2022-11-11"},"date":{"value":"2022-11-11"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{}}},{"name":"OQ320458","node_attrs":{"div":8,"accession":"OQ320458","author":{"author":"Gigante,C.,Cleavinger,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Burroughs,M.R.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Sinn,M.,Li,Y.","value":"Gigante,C.,Cleavinger,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Burroughs,M.R.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Sinn,M.,Li,Y."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_MO0002"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ320458/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T606-","G19458A","G149818A","T167929A","-179194A","-179195T","-179196A","-179197T","-179198A","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C185455T","A196614-"],"OPG034":["S183L"],"OPG176":["D4N"],"OPG193":["I199N"],"OPG210":["S1367L"]},"labels":{"aa":"OPG034: S183L; OPG176: D4N; OPG193: I199N; OPG210: S1367L"}}},{"name":"OR035719","node_attrs":{"div":7,"accession":"OR035719","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_113"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035719/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","C142797T","C167995T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G189258A"],"OPG164":["S7L"],"OPG193":["S221F"]},"labels":{"aa":"OPG164: S7L; OPG193: S221F"}}},{"name":"OQ957072","node_attrs":{"div":7,"accession":"OQ957072","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-3668E"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ957072/2023-02-16"},"date":{"value":"2023-02-16"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C35308T","G71777A","C120979T"],"OPG054":["R230H"],"OPG138":["D52N"]},"labels":{"aa":"OPG054: R230H; OPG138: D52N"}}},{"name":"NODE_0000158","node_attrs":{"div":5,"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G17023A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG029":["S16F"]},"labels":{"aa":"OPG029: S16F"}},"children":[{"name":"OQ696093","node_attrs":{"div":8,"accession":"OQ696093","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-29778O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ696093/2022-11-03"},"date":{"value":"2022-11-03"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C35308T","G102395A","G148319A"],"OPG054":["R230H"]},"labels":{"aa":"OPG054: R230H"}}},{"name":"NODE_0000159","node_attrs":{"div":8,"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G74462A","C80742T","G113382A"],"OPG094":["R228K"],"OPG104":["R93Q"]},"labels":{"aa":"OPG094: R228K; OPG104: R93Q"}},"children":[{"name":"OQ696101","node_attrs":{"div":8,"accession":"OQ696101","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-30628C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ696101/2022-11-11"},"date":{"value":"2022-11-11"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["-179265C","-179266A","-179267T","-179268G","-179269G","-179270A","-179271T","-179272A","-179273T","-179274C","-179275T","-179276T","-179277T","-179278A","-179279A","-179280A","-179281G","-179282A"]}}},{"name":"OQ696092","node_attrs":{"div":8,"accession":"OQ696092","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-29706O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ696092/2022-11-03"},"date":{"value":"2022-11-03"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["T196988-","A196989-","A196990-"]}}}]}]}]},{"name":"NODE_0000160","node_attrs":{"div":1,"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G111029A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]},"labels":{"clade":"B.1.6"}},"children":[{"name":"OP320554","node_attrs":{"div":3,"accession":"OP320554","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS-016"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP320554/2022-07-09"},"date":{"value":"2022-07-09"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{"nuc":["G25098A","A34289G"]}}},{"name":"OP320548","node_attrs":{"div":1,"accession":"OP320548","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS008"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP320548/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{}}},{"name":"OP320552","node_attrs":{"div":2,"accession":"OP320552","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS-012"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP320552/2022-07-06"},"date":{"value":"2022-07-06"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{"nuc":["C96110T"],"OPG117":["S21L"]},"labels":{"aa":"OPG117: S21L"}}},{"name":"OP320553","node_attrs":{"div":1,"accession":"OP320553","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS-013"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP320553/2022-07-08"},"date":{"value":"2022-07-08"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{}}},{"name":"OP320549","node_attrs":{"div":1,"accession":"OP320549","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS-010"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP320549/2022-07-02"},"date":{"value":"2022-07-02"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{}}},{"name":"OP431402","node_attrs":{"div":2,"accession":"OP431402","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-22752-O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP431402/2022-08-18"},"date":{"value":"2022-08-18"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G15814A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP642385","node_attrs":{"div":1,"accession":"OP642385","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-24910-O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642385/2022-09-09"},"date":{"value":"2022-09-09"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-"]}}},{"name":"OQ261706","node_attrs":{"div":1,"accession":"OQ261706","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-28353C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ261706/2022-10-14"},"date":{"value":"2022-10-14"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","T196852-","G196853-","T196854-"]}}},{"name":"OQ197863","node_attrs":{"div":2,"accession":"OQ197863","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Rosales,A.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Rosales,A.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"DC_INS_MPX-1122-H"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OQ197863/2022-10-22"},"date":{"value":"2022-10-22"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C151204T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"]}}},{"name":"OQ644785","node_attrs":{"div":8,"accession":"OQ644785","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00479/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ644785/2022-12-01"},"date":{"value":"2022-12-01"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A713-","G714-","T715-","C3375T","C35216T","C105831T","G134403A","C140075T","G158161A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C183982T","G187156A","G193835A","C196668-","T196669-","T196670-"],"OPG054":["D261N"],"OPG159":["S103F"],"OPG210":["T876M"]},"labels":{"aa":"OPG054: D261N; OPG159: S103F; OPG210: T876M"}}},{"name":"OP289783","node_attrs":{"div":1,"accession":"OP289783","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Mestanza,O.,Lope,P.,Nunez,A.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Mestanza,O.,Lope,P.,Nunez,A."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS-003"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP289783/2022-06-27"},"date":{"value":"2022-06-27"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{}}},{"name":"OP289782","node_attrs":{"div":1,"accession":"OP289782","author":{"author":"Silva,I.,Jimenez,V.,Hurtado,V.,Barcena,L.","value":"Silva,I.,Jimenez,V.,Hurtado,V.,Barcena,L."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS-001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP289782/2022-06-25"},"date":{"value":"2022-06-25"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-196615A","-196616A","-196617A"]}}},{"name":"OP320551","node_attrs":{"div":1,"accession":"OP320551","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS-018"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP320551/2022-07-09"},"date":{"value":"2022-07-09"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{}}},{"name":"OP320555","node_attrs":{"div":1,"accession":"OP320555","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS-021"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP320555/2022-07-09"},"date":{"value":"2022-07-09"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{}}},{"name":"OP320550","node_attrs":{"div":1,"accession":"OP320550","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS-015"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP320550/2022-07-09"},"date":{"value":"2022-07-09"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000161","node_attrs":{"div":7,"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C14098T","C84063T","G142493A","G151324A","C170573T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C187332T","C196696-","G196697-","A196698-"],"OPG163":["D98N"],"OPG198":["S179L"]},"labels":{"aa":"OPG163: D98N; OPG198: S179L"}},"children":[{"name":"OR499960","node_attrs":{"div":13,"accession":"OR499960","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00503/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499960/2023-03-15"},"date":{"value":"2023-03-15"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G6746A","C39266T","C63819T","G106927A","G138862A","G169213A"],"OPG083":["V300I"],"OPG125":["T243M"],"OPG156":["S183F"]},"labels":{"aa":"OPG083: V300I; OPG125: T243M; OPG156: S183F"}}},{"name":"NODE_0000162","node_attrs":{"div":9,"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G97749A","G188726A"]}},"children":[{"name":"OQ331003","node_attrs":{"div":9,"accession":"OQ331003","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00392/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ331003/2022-12-06"},"date":{"value":"2022-12-06"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OQ503814","node_attrs":{"div":11,"accession":"OQ503814","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00421/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ503814/2022-12-03"},"date":{"value":"2022-12-03"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A11160G","C108851T"],"OPG023":["F581L"],"OPG128":["D69N"]},"labels":{"aa":"OPG023: F581L; OPG128: D69N"}}}]}]},{"name":"NODE_0000163","node_attrs":{"div":2,"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G132863A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"]}},"children":[{"name":"OP642375","node_attrs":{"div":4,"accession":"OP642375","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-24590-C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642375/2022-09-07"},"date":{"value":"2022-09-07"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C29887T","C71451T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG091":["H28Y"]},"labels":{"aa":"OPG091: H28Y"}}},{"name":"OP881939","node_attrs":{"div":2,"accession":"OP881939","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-26719E"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP881939/2022-09-29"},"date":{"value":"2022-09-29"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-"]}}},{"name":"OQ148463","node_attrs":{"div":4,"accession":"OQ148463","author":{"author":"Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LBMB-UTP_MP-004_TOL"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"strain_display":{"value":"Colombia/OQ148463/2022-09-21"},"date":{"value":"2022-09-21"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G22646A","C85452T"],"OPG038":["P172S"],"OPG106":["G16E"]},"labels":{"aa":"OPG038: P172S; OPG106: G16E"}}},{"name":"OQ696099","node_attrs":{"div":5,"accession":"OQ696099","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-30518C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ696099/2022-11-09"},"date":{"value":"2022-11-09"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G63811A","G167862A","C170130T"],"OPG193":["D177N"]},"labels":{"aa":"OPG193: D177N"}}}]}]},{"name":"NODE_0000168","node_attrs":{"div":1,"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C70780T"]},"labels":{"clade":"B.1.5"}},"children":[{"name":"OP150925","node_attrs":{"div":1,"accession":"OP150925","author":{"author":"Gigante,C.,Xia,D.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y.","value":"Gigante,C.,Xia,D.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_GA001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP150925/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON959175","node_attrs":{"div":1,"accession":"ON959175","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI162"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/ON959175/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON959154","node_attrs":{"div":1,"accession":"ON959154","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI137"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/ON959154/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON918656","node_attrs":{"div":5,"accession":"ON918656","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Taiwan/110-231642/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"strain_display":{"value":"Taiwan/ON918656/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Taiwan"}},"branch_attrs":{"mutations":{"nuc":["C28702T","T34793C","T50861C","C51777T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG054":["T402A"],"OPG070":["V91A"],"OPG071":["E888K"]},"labels":{"aa":"OPG054: T402A; OPG070: V91A; OPG071: E888K"}}},{"name":"ON792322","node_attrs":{"div":1,"accession":"ON792322","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba64538/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"strain_display":{"value":"Switzerland/ON792322/2022-06-02"},"date":{"value":"2022-06-02"},"country":{"value":"Switzerland"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON780017","node_attrs":{"div":1,"accession":"ON780017","author":{"author":"Gramigna,G.,Giombini,E.,Gruber,C.E.M.,Rueca,M.,Carletti,F.,Cicalini,S.,Lapa,D.,Puro,V.,Marani,A.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Rivano Capparuccia,M.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F.","value":"Gramigna,G.,Giombini,E.,Gruber,C.E.M.,Rueca,M.,Carletti,F.,Cicalini,S.,Lapa,D.,Puro,V.,Marani,A.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Rivano Capparuccia,M.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"INMI-Pt4"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology"},"strain_display":{"value":"Italy/ON780017/2022-05-21"},"date":{"value":"2022-05-21"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A"]}}},{"name":"OP245318","node_attrs":{"div":5,"accession":"OP245318","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/PT0064/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP245318/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G71227A","C133867T","C134247T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G158866A"],"OPG090":["E17K"]},"labels":{"aa":"OPG090: E17K"}}},{"name":"OP536756","node_attrs":{"div":3,"accession":"OP536756","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000376"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536756/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C69888T","C150392T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG089":["S8L"],"OPG176":["S195F"]},"labels":{"aa":"OPG089: S8L; OPG176: S195F"}}},{"name":"OP555650","node_attrs":{"div":3,"accession":"OP555650","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0579/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555650/2022-09-10"},"date":{"value":"2022-09-10"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C41022T","A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159001A"],"OPG060":["R54K"],"OPG153":["D385-"],"OPG185":["D29N"]},"labels":{"aa":"OPG060: R54K; OPG153: D385-; OPG185: D29N"}}},{"name":"OP783902","node_attrs":{"div":1,"accession":"OP783902","author":{"author":"Laubscher,F.,Marques-Melancia,S.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Marques-Melancia,S.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-CH-38347314/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"strain_display":{"value":"Switzerland/OP783902/2022-06-08"},"date":{"value":"2022-06-08"},"country":{"value":"Switzerland"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ319135","node_attrs":{"div":1,"accession":"OQ319135","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI677"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ319135/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150562-","A150563-","T150564-","G150565-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OQ274885","node_attrs":{"div":1,"accession":"OQ274885","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI666"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ274885/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OQ274886","node_attrs":{"div":1,"accession":"OQ274886","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI667"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ274886/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OQ274884","node_attrs":{"div":1,"accession":"OQ274884","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI665"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ274884/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OQ274883","node_attrs":{"div":1,"accession":"OQ274883","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI664"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ274883/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OR264398","node_attrs":{"div":5,"accession":"OR264398","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"34_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264398/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["C30283T","C37054T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","G179589A","G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N"}}},{"name":"NODE_0000169","node_attrs":{"div":2,"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C25644T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}},"children":[{"name":"ON637939","node_attrs":{"div":2,"accession":"ON637939","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI02"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON637939/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A169745-","C169746-","A169747-","G169748-","A169749-","T169750-","A169751-","C169752-","A169753-","G169754-","A169755-","T169756-","A169757-","C169758-","A169759-","G169760-","A169761-","T169762-","A169763-","C169764-","A169765-","G169766-","A169767-","T169768-","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-"],"OPG197":["T26-","D27-","T28-","D29-","T30-","D31-","T32-","D33-","T34-","D35-"]},"labels":{"aa":"OPG197: T26-, D27-, T28-, D29-, T30-, D31-, T32-, D33-, T34-, D35-"}}},{"name":"OQ773463","node_attrs":{"div":4,"accession":"OQ773463","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI844"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ773463/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150564-","G150565-","G156469A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","C190668T"],"OPG016":["R87*"]},"labels":{"aa":"OPG016: R87*"}}}]},{"name":"NODE_0000170","node_attrs":{"div":4,"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G111379A","C160426T","G165326A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A"],"OPG130":["S175L"],"OPG190":["E69K"]},"labels":{"aa":"OPG130: S175L; OPG190: E69K"}},"children":[{"name":"OQ320464","node_attrs":{"div":4,"accession":"OQ320464","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_NY0025"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ320464/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OQ721933","node_attrs":{"div":5,"accession":"OQ721933","author":{"author":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y.","value":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_OH0005"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ721933/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G48045A","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","G173318-","G173319-","G173320-","C173321-","A173322-","A173323-","A173324-","A173325-","C173326-","A173327-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"]}}},{"name":"OQ721932","node_attrs":{"div":9,"accession":"OQ721932","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_NY0046"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ721932/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","G74391A","G98473A","C124495T","C132962T","C149264T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-196615A"],"OPG094":["M204I"],"OPG118":["D10N"]},"labels":{"aa":"OPG094: M204I; OPG118: D10N"}}}]},{"name":"NODE_0000171","node_attrs":{"div":2,"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C44333T","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG064":["M522I"]},"labels":{"aa":"OPG064: M522I"}},"children":[{"name":"ON853667","node_attrs":{"div":3,"accession":"ON853667","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI085"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/ON853667/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G46956A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"],"OPG066":["P158L"]},"labels":{"aa":"OPG066: P158L"}}},{"name":"OR035702","node_attrs":{"div":6,"accession":"OR035702","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_96"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035702/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C29315T","C60396T","G149807A","C161572T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG046":["D139N"]},"labels":{"aa":"OPG046: D139N"}}},{"name":"OR035675","node_attrs":{"div":3,"accession":"OR035675","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_69"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035675/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G161488A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000172","node_attrs":{"div":3,"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G93512T"],"OPG113":["K594N"]},"labels":{"aa":"OPG113: K594N"}},"children":[{"name":"OP358276","node_attrs":{"div":6,"accession":"OP358276","author":{"author":"Tramuto,F.","value":"Tramuto,F."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"SIC-AOUP-UNIPA_VL_9aug"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University of Palermo, Department of Health Promotion Sciences Maternal and Infant Care, Internal Medicine and Medical Specialties \"G. D'Alessandro\"\"\""},"strain_display":{"value":"Italy/OP358276/2022-08-09"},"date":{"value":"2022-08-09"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["C33103T","C114490T","C133295T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-"],"OPG049":["E17K"],"OPG133":["D403N"]},"labels":{"aa":"OPG049: E17K; OPG133: D403N"}}},{"name":"OR264417","node_attrs":{"div":4,"accession":"OR264417","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"43_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264417/2022-06-22"},"date":{"value":"2022-06-22"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["G2898A","C194312T"]}}}]}]}]},{"name":"NODE_0000173","node_attrs":{"div":2,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C89906T","G94798A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG110":["S92F"],"OPG115":["E47K"]},"labels":{"aa":"OPG110: S92F; OPG115: E47K","clade":"B.1.10"}},"children":[{"name":"ON720848","node_attrs":{"div":3,"accession":"ON720848","author":{"author":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/Spain/MD-HGUGM-6513479/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Microbial Genomics, Hospital General Universitario Gregorio Marañón, Madrid, Spain"},"strain_display":{"value":"Spain/ON720848/2022-05-27"},"date":{"value":"2022-05-27"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["A327-","T605-","T606-","A1697-","T4296-","T6587-","T6588-","T7253-","G7724-","T8017-","A8036-","T8499-","T9514-","A9869-","T10502-","A10914-","T11188-","C11749-","T11761-","T12121-","A15754-","A17087-","T18866-","A19360-","T20663-","A21081-","T21975-","T24678-","T25853-","T26099-","C27002-","A27114-","C27799-","A28529-","A28530-","T32194-","T33414-","G35949-","T37982-","T39131-","T39866-","T41744-","T42990-","C43014-","G43200-","A43443-","T44120-","T44738-","G46762-","T48675-","A49134-","G49833-","A51022-","A52765-","A54968-","A55124-","T55560-","T56040-","T57075-","A57277-","A58650-","T61749-","A62041-","T63628-","A64728-","A64935-","A65535-","A65967-","T66783-","A66843-","A67164-","C68466-","T68481-","C68899-","G69145-","A69744-","T69768-","A71254-","G71359-","T75833-","A76072-","T76084-","T76085-","A76153-","A76154-","A76890-","A77260-","T77803-","T78062-","A79042-","A79181-","G79217-","C79533T","A79787-","G80950-","C82482-","T84846-","T88095-","T88836-","T88941-","A89106-","T90646-","T91129-","T91370-","A91583-","A91705-","T94795-","A95341-","A95574-","G95742-","G95818-","A97351-","A97480-","A97501-","A97699-","A98683-","T101452-","G101515-","T102437-","T103367-","T103368-","T104279-","T105360-","T106596-","T108598-","A113921-","T113951-","C114431-","T114518-","T114755-","T115127-","G115801-","A116014-","C116494-","T116963-","T121121-","T121122-","G121269-","C121546-","T124022-","T124751-","A125252-","A126568-","T126682-","A126715-","A127250-","A127754-","A132023-","A132024-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133639-","T136780-","T137886-","A143045-","G143363-","T143478-","A144230-","T146131-","A148000-","A149727-","A150340-","T150538-","T150539-","A150635-","T150864-","A151490-","A151508-","G151545-","A152676-","T152686-","A153358-","A153424-","A153517-","T154862-","T155424-","C156607-","C156608-","A157997-","T163498-","T163597-","A163957-","A165461-","A166740-","G167640-","A167967-","T168120-","A170728-","T170758-","T170903-","T170904-","T172087-","T172667-","G179036-","A179551-","A179950-","T180905-","G181052-","A181253-","C183534-","A183780-","T187080-","A190935-","A191015-","G191519-","A196613-","A196614-","T196888-","T197183-"],"OPG015_dup":["G156-"],"OPG016":["T176-"],"OPG019":["G49-"],"OPG021":["N95-"],"OPG023":["G385-"],"OPG043":["G53-"],"OPG044":["K147-"],"OPG066":["P223-"],"OPG068":["L159-","D545-"],"OPG070":["N145-"],"OPG074":["K523-"],"OPG084":["K3-","K272-","R416-"],"OPG085":["F457-"],"OPG087":["L15-","G97-"],"OPG090":["K26-"],"OPG096":["L83-"],"OPG098":["S121-"],"OPG099":["F47-"],"OPG100":["F19-"],"OPG102":["K33-"],"OPG104":["P24-"],"OPG109":["K206-"],"OPG111":["F128-"],"OPG112":["S42-"],"OPG115":["S46-"],"OPG116":["K72-"],"OPG117":["K435-","N478-","R551-"],"OPG118":["I80-"],"OPG122":["Y4-"],"OPG123":["K569-"],"OPG133":["K394-"],"OPG134":["E18-","P249-"],"OPG139":["P34-"],"OPG145":["F26-","F269-","I436-"],"OPG148":["I195-","F233-"],"OPG149":["K19-"],"OPG151":["K1034-"],"OPG164":["R90-"],"OPG165":["M239-"],"OPG172":["I192-"],"OPG175":["N96-"],"OPG176":["K178-"],"OPG178":["D13-"],"OPG180":["K223-","K276-"],"OPG181":["F151-"],"OPG189":["L56-","K209-"],"OPG190":["N114-"],"OPG192":["K4-"],"OPG193":["G103-","F263-"],"OPG198":["K231-"],"OPG208":["I96-"],"OPG209":["L130-"],"OPG210":["P727-"]},"labels":{"aa":"OPG015_dup: G156-; OPG016: T176-; OPG019: G49-; OPG021: N95-; OPG023: G385-; OPG043: G53-; OPG044: K147-; OPG066: P223-; OPG068: L159-, D545-; OPG070: N145-; OPG074: K523-; OPG084: K3-, K272-, R416-; OPG085: F457-; OPG087: L15-, G97-; OPG090: K26-; OPG096: L83-; OPG098: S121-; OPG099: F47-; OPG100: F19-; OPG102: K33-; OPG104: P24-; OPG109: K206-; OPG111: F128-; OPG112: S42-; OPG115: S46-; OPG116: K72-; OPG117: K435-, N478-, R551-; OPG118: I80-; OPG122: Y4-; OPG123: K569-; OPG133: K394-; OPG134: E18-, P249-; OPG139: P34-; OPG145: F26-, F269-, I436-; OPG148: I195-, F233-; OPG149: K19-; OPG151: K1034-; OPG164: R90-; OPG165: M239-; OPG172: I192-; OPG175: N96-; OPG176: K178-; OPG178: D13-; OPG180: K223-, K276-; OPG181: F151-; OPG189: L56-, K209-; OPG190: N114-; OPG192: K4-; OPG193: G103-, F263-; OPG198: K231-; OPG208: I96-; OPG209: L130-; OPG210: P727-"}}},{"name":"OP205110","node_attrs":{"div":2,"accession":"OP205110","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000147"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205110/2022-06-14"},"date":{"value":"2022-06-14"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OR035722","node_attrs":{"div":5,"accession":"OR035722","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_116"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035722/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C20879T","C60094T","T133102-","G149818A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","T196712-","A196713-","T196714-"],"OPG036":["M62I"],"OPG080":["R642K"],"OPG176":["D4N"]},"labels":{"aa":"OPG036: M62I; OPG080: R642K; OPG176: D4N"}}},{"name":"OQ581847","node_attrs":{"div":15,"accession":"OQ581847","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0005b/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"strain_display":{"value":"Spain/OQ581847/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["A43453G","A66769C","T88735A","G90070A","C101656T","G104325A","C121681T","G127869A","G132490A","T133095A","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T139779C","G140866T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C151204T","T176743A"],"OPG063":["L79P"],"OPG085":["V588G"],"OPG109":["E238V"],"OPG110":["D147N"],"OPG123":["A249V"],"OPG150":["G31R"],"OPG160":["S70Y"],"OPG205":["L363*"]},"labels":{"aa":"OPG063: L79P; OPG085: V588G; OPG109: E238V; OPG110: D147N; OPG123: A249V; OPG150: G31R; OPG160: S70Y; OPG205: L363*"}}},{"name":"OR264420","node_attrs":{"div":3,"accession":"OR264420","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"45_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264420/2022-07-10"},"date":{"value":"2022-07-10"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["G63147A","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"NODE_0000174","node_attrs":{"div":3,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C150831T"]}},"children":[{"name":"ON959143","node_attrs":{"div":4,"accession":"ON959143","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX-96/Finland/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"strain_display":{"value":"Finland/ON959143/2022-06-16"},"date":{"value":"2022-06-16"},"country":{"value":"Finland"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C188491T"]}}},{"name":"OP382489","node_attrs":{"div":4,"accession":"OP382489","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00012"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382489/2022-07-19"},"date":{"value":"2022-07-19"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["G109437A","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","G150603-","A150604-","T150605-","A150606-","T150607-","G150608-","A150609-","T150610-","G150611-"],"OPG129":["S523L"],"OPG153":["D384-","D385-"]},"labels":{"aa":"OPG129: S523L; OPG153: D384-, D385-"}}}]},{"name":"NODE_0000175","node_attrs":{"div":3,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G50672A"],"OPG070":["R28K"]},"labels":{"aa":"OPG070: R28K"}},"children":[{"name":"OP642386","node_attrs":{"div":4,"accession":"OP642386","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-24913-O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642386/2022-09-09"},"date":{"value":"2022-09-09"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C121034T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP642392","node_attrs":{"div":3,"accession":"OP642392","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-24520-O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642392/2022-09-07"},"date":{"value":"2022-09-07"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP642388","node_attrs":{"div":3,"accession":"OP642388","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-24915-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642388/2022-09-09"},"date":{"value":"2022-09-09"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP693650","node_attrs":{"div":4,"accession":"OP693650","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT_INS_MPX_0024_L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP693650/2022-08-07"},"date":{"value":"2022-08-07"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G93624A"],"OPG113":["E632K"]},"labels":{"aa":"OPG113: E632K"}}},{"name":"OP642408","node_attrs":{"div":3,"accession":"OP642408","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-25285O"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642408/2022-09-13"},"date":{"value":"2022-09-13"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-"]}}},{"name":"OQ261707","node_attrs":{"div":4,"accession":"OQ261707","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-28354C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ261707/2022-10-14"},"date":{"value":"2022-10-14"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G148202A"],"OPG173":["E56K"]},"labels":{"aa":"OPG173: E56K"}}},{"name":"OQ148472","node_attrs":{"div":5,"accession":"OQ148472","author":{"author":"Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LBMB-UTP_MP-019_VAC"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"strain_display":{"value":"Colombia/OQ148472/2022-11-11"},"date":{"value":"2022-11-11"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C25087T","C62649T"],"OPG040":["R131K"]},"labels":{"aa":"OPG040: R131K"}}},{"name":"NODE_0000176","node_attrs":{"div":4,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G68499A"]}},"children":[{"name":"OQ261709","node_attrs":{"div":6,"accession":"OQ261709","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-28766E"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ261709/2022-10-21"},"date":{"value":"2022-10-21"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C15945T","C158835T","A197010-","T197011-","G197012-"],"OPG027":["D145N"]},"labels":{"aa":"OPG027: D145N"}}},{"name":"OQ261701","node_attrs":{"div":4,"accession":"OQ261701","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-28290C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ261701/2022-10-13"},"date":{"value":"2022-10-13"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","A197133-","T197134-","T197135-"]}}}]},{"name":"NODE_0000177","node_attrs":{"div":8,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","G32863A","G45416A","C72770T","C123118T","C148771T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG092":["E60K"],"OPG174":["D209N"]},"labels":{"aa":"OPG092: E60K; OPG174: D209N"}},"children":[{"name":"OQ696103","node_attrs":{"div":8,"accession":"OQ696103","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-31501C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ696103/2022-11-22"},"date":{"value":"2022-11-22"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{}}},{"name":"OQ696098","node_attrs":{"div":11,"accession":"OQ696098","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-30513C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ696098/2022-11-10"},"date":{"value":"2022-11-10"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A50672G","C67823T","A94798G"],"OPG070":["K28R"],"OPG085":["E237K"],"OPG115":["K47E"]},"labels":{"aa":"OPG070: K28R; OPG085: E237K; OPG115: K47E"}}}]},{"name":"NODE_0000178","node_attrs":{"div":4,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C13624T","-179194A","-179195T","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-"]}},"children":[{"name":"OP642403","node_attrs":{"div":5,"accession":"OP642403","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-25254C"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642403/2022-09-13"},"date":{"value":"2022-09-13"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C120170T","G133051A"],"OPG137":["S190L"]},"labels":{"aa":"OPG137: S190L"}}},{"name":"NODE_0000179","node_attrs":{"div":5,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C43472T","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG063":["E73K"]},"labels":{"aa":"OPG063: E73K"}},"children":[{"name":"OP642398","node_attrs":{"div":5,"accession":"OP642398","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-24939C"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642398/2022-09-12"},"date":{"value":"2022-09-12"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{}}},{"name":"OP689664","node_attrs":{"div":5,"accession":"OP689664","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI511"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP689664/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-181355C","-181356A","-181357T","-181358G","-181359A","-181360A","-181361T","-181362T","-181363T","-181364T","-181365C","-181366A","-181367G","-181368A","-181369A","-181370A","-181371T","-181372T"]}}}]}]},{"name":"NODE_0000180","node_attrs":{"div":4,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C49265T"]}},"children":[{"name":"OP459217","node_attrs":{"div":7,"accession":"OP459217","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-23654-O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"strain_display":{"value":"Colombia/OP459217/2022-08-30"},"date":{"value":"2022-08-30"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C113965T","G150800A","C152191T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG133":["E578K"]},"labels":{"aa":"OPG133: E578K"}}},{"name":"OP819958","node_attrs":{"div":4,"accession":"OP819958","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"QUI_INS_MPX_0967_L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP819958/2022-10-15"},"date":{"value":"2022-10-15"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G150603-","A150604-","T150605-","A150606-","T150607-","G150608-","A150609-","T150610-","G150611-"]}}},{"name":"OQ261695","node_attrs":{"div":7,"accession":"OQ261695","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-28157C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ261695/2022-10-12"},"date":{"value":"2022-10-12"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A1701-","C1702-","T1703-","G7959A","C19990T","G164476A","T196852-","G196853-","T196854-"],"OPG019":["R127Q"],"OPG034":["D6N"],"OPG189":["E382K"]},"labels":{"aa":"OPG019: R127Q; OPG034: D6N; OPG189: E382K"}}},{"name":"OP959057","node_attrs":{"div":5,"accession":"OP959057","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"SUC-UNIMOL-MPX-293401-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"strain_display":{"value":"Colombia/OP959057/2022-11-10"},"date":{"value":"2022-11-10"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G23118A"]}}},{"name":"NODE_0000181","node_attrs":{"div":5,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C100007T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG118":["S521F"]},"labels":{"aa":"OPG118: S521F"}},"children":[{"name":"OP536764","node_attrs":{"div":5,"accession":"OP536764","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000385"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536764/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-180517A","-180518A","-180519T","-180520G","-180521A","-180522C","-180523G","-180524A","-180525T","-180526A","-180527T","-180528A","-180529C","-180530G","-180531G","-180532A","-180533T","-180534T","A196614-"]}}},{"name":"OP477453","node_attrs":{"div":5,"accession":"OP477453","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-23188-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP477453/2022-08-23"},"date":{"value":"2022-08-23"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{}}},{"name":"OP642379","node_attrs":{"div":5,"accession":"OP642379","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-24713-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642379/2022-09-08"},"date":{"value":"2022-09-08"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000182","node_attrs":{"div":1,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G34308A"],"OPG053":["S128L"]},"labels":{"aa":"OPG053: S128L","clade":"B.1.4"}},"children":[{"name":"ON803417","node_attrs":{"div":3,"accession":"ON803417","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2836/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON803417/2022-05-17"},"date":{"value":"2022-05-17"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C69127T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G158750A"],"OPG087":["R91W"]},"labels":{"aa":"OPG087: R91W"}}},{"name":"OP390177","node_attrs":{"div":2,"accession":"OP390177","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ATL-UNIMOL-MPX-292896-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"strain_display":{"value":"Colombia/OP390177/2022-08-13"},"date":{"value":"2022-08-13"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C176447T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OQ503748","node_attrs":{"div":6,"accession":"OQ503748","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-108160/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OQ503748/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","G36259A","A80755C","G159203A","G174543A","C177720T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG104":["C89G"],"OPG185":["G96E"],"OPG205":["R689C"]},"labels":{"aa":"OPG104: C89G; OPG185: G96E; OPG205: R689C"}}},{"name":"NODE_0000183","node_attrs":{"div":2,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T85846C"],"OPG107":["M112T"]},"labels":{"aa":"OPG107: M112T"}},"children":[{"name":"ON880532","node_attrs":{"div":2,"accession":"ON880532","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3253/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880532/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C133187-","A133188-","T133189-","T133190-","T133191-","C133192-","A133193-"]}}},{"name":"ON880519","node_attrs":{"div":2,"accession":"ON880519","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2833/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880519/2022-05-13"},"date":{"value":"2022-05-13"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000184","node_attrs":{"div":4,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C10672T","G112481A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G163626A"],"OPG022":["E63K"]},"labels":{"aa":"OPG022: E63K"}},"children":[{"name":"NODE_0000185","node_attrs":{"div":5,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A87705G"]}},"children":[{"name":"OR126132","node_attrs":{"div":8,"accession":"OR126132","author":{"author":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C.","value":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"HRYC_MPXV002"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Hospital Ramon y Cajal, Microbiology"},"strain_display":{"value":"Spain/OR126132/2023-03-23"},"date":{"value":"2023-03-23"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["G6376A","G11924A","G21674A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C190834T"],"OPG016":["S142L"],"OPG023":["S326L"],"OPG037":["L254F"]},"labels":{"aa":"OPG016: S142L; OPG023: S326L; OPG037: L254F"}}},{"name":"OR759209","node_attrs":{"div":5,"accession":"OR759209","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL121/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759209/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000186","node_attrs":{"div":6,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C99441T"]}},"children":[{"name":"OR759187","node_attrs":{"div":8,"accession":"OR759187","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL099/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759187/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C153642T","C183429T"],"OPG210":["P692S"]},"labels":{"aa":"OPG210: P692S"}}},{"name":"NODE_0000187","node_attrs":{"div":7,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C111569T"],"OPG130":["D112N"]},"labels":{"aa":"OPG130: D112N"}},"children":[{"name":"OR759185","node_attrs":{"div":7,"accession":"OR759185","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL097/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759185/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"OR759175","node_attrs":{"div":7,"accession":"OR759175","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL087/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759175/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T"]}}},{"name":"OR759157","node_attrs":{"div":7,"accession":"OR759157","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL068/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759157/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000188","node_attrs":{"div":5,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G144478A"]}},"children":[{"name":"ON880511","node_attrs":{"div":5,"accession":"ON880511","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3214/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880511/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"]}}},{"name":"OR759193","node_attrs":{"div":5,"accession":"OR759193","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL105/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759193/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"OR759168","node_attrs":{"div":6,"accession":"OR759168","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL080/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759168/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C4150T","G193060A"],"OPG003":["S153N"],"OPG003_dup":["S153N"]},"labels":{"aa":"OPG003: S153N; OPG003_dup: S153N"}}},{"name":"NODE_0000189","node_attrs":{"div":6,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C143461T"]}},"children":[{"name":"OR759212","node_attrs":{"div":6,"accession":"OR759212","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL124/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759212/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["T606-","A196614-"]}}},{"name":"OR759148","node_attrs":{"div":6,"accession":"OR759148","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL052/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759148/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T","-196615A"]}}}]},{"name":"NODE_0000190","node_attrs":{"div":6,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G170076A"]}},"children":[{"name":"OR759176","node_attrs":{"div":8,"accession":"OR759176","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL088/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759176/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T","C128534T","C151626T"],"OPG178":["Q40*"]},"labels":{"aa":"OPG178: Q40*"}}},{"name":"OR759174","node_attrs":{"div":6,"accession":"OR759174","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL086/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759174/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000191","node_attrs":{"div":5,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C24995T","G85774A","G148427A","G189258A"],"OPG040":["D162N"],"OPG107":["R88K"]},"labels":{"aa":"OPG040: D162N; OPG107: R88K"}},"children":[{"name":"ON983164","node_attrs":{"div":6,"accession":"ON983164","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3558/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON983164/2022-06-09"},"date":{"value":"2022-06-09"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["G167106A"],"OPG192":["E126K"]},"labels":{"aa":"OPG192: E126K"}}},{"name":"ON983163","node_attrs":{"div":5,"accession":"ON983163","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3532/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON983163/2022-06-07"},"date":{"value":"2022-06-07"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"ON880505","node_attrs":{"div":5,"accession":"ON880505","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2906/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880505/2022-05-20"},"date":{"value":"2022-05-20"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"OP279048","node_attrs":{"div":6,"accession":"OP279048","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-4155/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP279048/2022-06-29"},"date":{"value":"2022-06-29"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C120198T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP279035","node_attrs":{"div":5,"accession":"OP279035","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-4103/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP279035/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP279033","node_attrs":{"div":9,"accession":"OP279033","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-4094/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP279033/2022-07-06"},"date":{"value":"2022-07-06"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","G8373A","C19191T","G103142A","C105161T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A"],"OPG122":["E239K"],"OPG124":["D270N"]},"labels":{"aa":"OPG122: E239K; OPG124: D270N"}}},{"name":"OR759221","node_attrs":{"div":5,"accession":"OR759221","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL133/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759221/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR759227","node_attrs":{"div":7,"accession":"OR759227","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL141/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759227/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["G16076A","G106482A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG027":["S101F"]},"labels":{"aa":"OPG027: S101F"}}},{"name":"OR759211","node_attrs":{"div":6,"accession":"OR759211","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL123/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759211/2022-06-01"},"date":{"value":"2022-06-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G172501A"],"OPG200":["E118K"]},"labels":{"aa":"OPG200: E118K"}}},{"name":"OR759192","node_attrs":{"div":5,"accession":"OR759192","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL104/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759192/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR759177","node_attrs":{"div":11,"accession":"OR759177","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL089/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759177/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T","C13331T","G62952A","G67225A","G100442A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G178818A","C181598T","-196615A"],"OPG085":["S436L"]},"labels":{"aa":"OPG085: S436L"}}},{"name":"OR759156","node_attrs":{"div":6,"accession":"OR759156","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL066/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759156/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T","C923A","G127179A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G196287T","-196615A"],"OPG001":["G218V"],"OPG001_dup":["G218V"]},"labels":{"aa":"OPG001: G218V; OPG001_dup: G218V"}}},{"name":"NODE_0000192","node_attrs":{"div":7,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C24282T","G28334A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG044":["E82K"]},"labels":{"aa":"OPG044: E82K"}},"children":[{"name":"OR759181","node_attrs":{"div":8,"accession":"OR759181","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL093/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759181/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C47672T"]}}},{"name":"OR759182","node_attrs":{"div":7,"accession":"OR759182","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL094/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759182/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-196615A"]}}}]},{"name":"NODE_0000193","node_attrs":{"div":6,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G45236A"]}},"children":[{"name":"OP279043","node_attrs":{"div":6,"accession":"OP279043","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-4140/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP279043/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR759203","node_attrs":{"div":6,"accession":"OR759203","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL115/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759203/2022-06-01"},"date":{"value":"2022-06-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR759184","node_attrs":{"div":7,"accession":"OR759184","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL096/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759184/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["G132531A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}}]}]}]},{"name":"NODE_0000194","node_attrs":{"div":1,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C25644T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]},"labels":{"clade":"B.1.7"}},"children":[{"name":"OP205106","node_attrs":{"div":1,"accession":"OP205106","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000143"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205106/2022-06-16"},"date":{"value":"2022-06-16"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OP205101","node_attrs":{"div":2,"accession":"OP205101","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000136"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205101/2022-07-07"},"date":{"value":"2022-07-07"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C174227T"]}}},{"name":"OP205090","node_attrs":{"div":1,"accession":"OP205090","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000102"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205090/2022-06-13"},"date":{"value":"2022-06-13"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OP205081","node_attrs":{"div":1,"accession":"OP205081","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000078"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205081/2022-06-14"},"date":{"value":"2022-06-14"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OP415182","node_attrs":{"div":4,"accession":"OP415182","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_Yob5K4_9000201"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415182/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["G56745A","C88394T","G187367A"],"OPG109":["E352K"]},"labels":{"aa":"OPG109: E352K"}}},{"name":"OP415181","node_attrs":{"div":1,"accession":"OP415181","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_dTfiMV_9000200"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415181/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OP536814","node_attrs":{"div":2,"accession":"OP536814","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000452"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536814/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["A57256G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OP536801","node_attrs":{"div":3,"accession":"OP536801","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000429"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536801/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G160946A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G180608A","T190787-"],"OPG187":["D109N"],"OPG209":["E31K"]},"labels":{"aa":"OPG187: D109N; OPG209: E31K"}}},{"name":"OP536778","node_attrs":{"div":7,"accession":"OP536778","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000400"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536778/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T606-","C66249T","G69081A","C88644A","C104134T","C112638T","A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G186489A","A196614-"],"OPG109":["K268N"],"OPG123":["A313T"],"OPG153":["D385-"],"OPG210":["D1712N"]},"labels":{"aa":"OPG109: K268N; OPG123: A313T; OPG153: D385-; OPG210: D1712N"}}},{"name":"OP536774","node_attrs":{"div":3,"accession":"OP536774","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000396"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536774/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-607T","G50034A","G74200A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A"],"OPG069":["E17K"],"OPG094":["D141N"]},"labels":{"aa":"OPG069: E17K; OPG094: D141N"}}},{"name":"OP536665","node_attrs":{"div":2,"accession":"OP536665","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-USA-IL-IDPH-004"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"strain_display":{"value":"USA/OP536665/2022-06-14"},"date":{"value":"2022-06-14"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G12169A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A","-196616A","-196617A"]}}},{"name":"OP604567","node_attrs":{"div":5,"accession":"OP604567","author":{"author":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T.","value":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV22/human/USA-OK-288"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"strain_display":{"value":"USA/OP604567/2022-09-12"},"date":{"value":"2022-09-12"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G4236A","C9781T","G49824A","C57550T","A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C192974T","-196615A","-196616A","-196617A"],"OPG068":["E542K"],"OPG153":["D385-"]},"labels":{"aa":"OPG068: E542K; OPG153: D385-"}}},{"name":"OR759205","node_attrs":{"div":1,"accession":"OR759205","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL117/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759205/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"ON843170","node_attrs":{"div":1,"accession":"ON843170","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0031/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/ON843170/2022-05-26"},"date":{"value":"2022-05-26"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP205070","node_attrs":{"div":1,"accession":"OP205070","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000064"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205070/2022-06-06"},"date":{"value":"2022-06-06"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000195","node_attrs":{"div":2,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G120241A"],"OPG137":["D214N"]},"labels":{"aa":"OPG137: D214N"}},"children":[{"name":"ON911481","node_attrs":{"div":5,"accession":"ON911481","author":{"author":"Galan-Huerta,K.A.,Paz-Infanzon,M.,Ruiz-Higareda,A.F.,Nuzzolo-Shihadeh,L.,Camacho-Ortiz,A.,Bocanegra-Ibarias,P.,Rivas-Estilla,A.M.,Zacarias-Villarreal,D.,Yamallel-Ortega,L.A.,Guerrero-Putz,M.D.,Ocampo-Candiani,J.","value":"Galan-Huerta,K.A.,Paz-Infanzon,M.,Ruiz-Higareda,A.F.,Nuzzolo-Shihadeh,L.,Camacho-Ortiz,A.,Bocanegra-Ibarias,P.,Rivas-Estilla,A.M.,Zacarias-Villarreal,D.,Yamallel-Ortega,L.A.,Guerrero-Putz,M.D.,Ocampo-Candiani,J."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/MX-UANL001/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Universidad Autonoma de Nuevo Leon - Facultad de Medicina, Centro de Investigacion e Innovacion en Virologia Medica"},"strain_display":{"value":"Mexico/ON911481/2022-06-28"},"date":{"value":"2022-06-28"},"country":{"value":"Mexico"}},"branch_attrs":{"mutations":{"nuc":["T606-","G57088A","C127530T","T133098-","T133099-","T133100-","T133101-","T133102-","T168120C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A","-196616A","-196617A"],"OPG074":["S13L"],"OPG149":["S112L"],"OPG193":["F263L"]},"labels":{"aa":"OPG074: S13L; OPG149: S112L; OPG193: F263L"}}},{"name":"OP205071","node_attrs":{"div":2,"accession":"OP205071","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000065"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205071/2022-06-06"},"date":{"value":"2022-06-06"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OQ773452","node_attrs":{"div":2,"accession":"OQ773452","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI833"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ773452/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-"]}}}]},{"name":"NODE_0000198","node_attrs":{"div":3,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G144556A","C170573T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}},"children":[{"name":"OR264460","node_attrs":{"div":3,"accession":"OR264460","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"7_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264460/2022-07-11"},"date":{"value":"2022-07-11"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}},{"name":"OR264459","node_attrs":{"div":3,"accession":"OR264459","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"7_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264459/2022-07-11"},"date":{"value":"2022-07-11"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}},{"name":"OR264370","node_attrs":{"div":3,"accession":"OR264370","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"18_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264370/2022-07-11"},"date":{"value":"2022-07-11"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000199","node_attrs":{"div":2,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G63147A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}},"children":[{"name":"OP536792","node_attrs":{"div":5,"accession":"OP536792","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000418"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536792/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C15004T","C101845T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177780A","-179194A","-179195T","-179196A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG121":["S19F"],"OPG205":["E709K"]},"labels":{"aa":"OPG121: S19F; OPG205: E709K"}}},{"name":"OR264425","node_attrs":{"div":2,"accession":"OR264425","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"48_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264425/2022-08-31"},"date":{"value":"2022-08-31"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000200","node_attrs":{"div":6,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G10224A","G129761A","T143625A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C177847T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","-196615A"],"OPG021":["R213Q"],"OPG151":["D280N"],"OPG165":["I37N"],"OPG205":["S731L"]},"labels":{"aa":"OPG021: R213Q; OPG151: D280N; OPG165: I37N; OPG205: S731L"}},"children":[{"name":"ON927248","node_attrs":{"div":6,"accession":"ON927248","author":{"author":"Chan,W.Y.,Mtshali,P.S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J.","value":"Chan,W.Y.,Mtshali,P.S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"NICD-SVPL232"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Africa"},"institution":{"value":"National Institute for Communicable Disease, Sequencing core facility"},"strain_display":{"value":"South Africa/ON927248/2022-06-24"},"date":{"value":"2022-06-24"},"country":{"value":"South Africa"}},"branch_attrs":{"mutations":{"nuc":["A196601C"]}}},{"name":"ON918611","node_attrs":{"div":6,"accession":"ON918611","author":{"author":"Chan,W.Y.,Mtshali,S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J.","value":"Chan,W.Y.,Mtshali,S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"NICD-SVPL223"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Africa"},"institution":{"value":"National Institute for Communicable Disease, Sequencing Core Facility"},"strain_display":{"value":"South Africa/ON918611/2022-06-20"},"date":{"value":"2022-06-20"},"country":{"value":"South Africa"}},"branch_attrs":{"mutations":{"nuc":["-607T"]}}}]}]},{"name":"NODE_0000201","node_attrs":{"div":2,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C14077T"]}},"children":[{"name":"OP205084","node_attrs":{"div":4,"accession":"OP205084","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000093"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205084/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C4529T","G155585A","G192681A"],"OPG003":["D27N"],"OPG003_dup":["D27N"]},"labels":{"aa":"OPG003: D27N; OPG003_dup: D27N"}}},{"name":"OP415186","node_attrs":{"div":2,"accession":"OP415186","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_cmjxZM_9000205"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415186/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000202","node_attrs":{"div":3,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G147799A"],"OPG172":["A125T"]},"labels":{"aa":"OPG172: A125T"}},"children":[{"name":"OP205097","node_attrs":{"div":5,"accession":"OP205097","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000130"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205097/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["G37691A","G157353A"]}}},{"name":"OP415199","node_attrs":{"div":3,"accession":"OP415199","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_K1dQNt_9000223"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415199/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000203","node_attrs":{"div":2,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C148771T","A179191-","T179192-","T179193-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG174":["D209N"]},"labels":{"aa":"OPG174: D209N"}},"children":[{"name":"OR449630","node_attrs":{"div":4,"accession":"OR449630","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI916"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR449630/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G69840A","C99542T","G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG118":["S366F"],"OPG193":["F263-"]},"labels":{"aa":"OPG118: S366F; OPG193: F263-"}}},{"name":"NODE_0000204","node_attrs":{"div":3,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G114316A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG133":["H461Y"]},"labels":{"aa":"OPG133: H461Y"}},"children":[{"name":"OR087006","node_attrs":{"div":7,"accession":"OR087006","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_197/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR087006/2022-08-03"},"date":{"value":"2022-08-03"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C12637T","G53377A","T133102-","C178569T","-179191A","-179192T","-179193T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C182707T"],"OPG210":["S451F"]},"labels":{"aa":"OPG210: S451F"}}},{"name":"NODE_0000205","node_attrs":{"div":4,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G152437A"]}},"children":[{"name":"OQ159026","node_attrs":{"div":5,"accession":"OQ159026","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI631"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ159026/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150547A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","G187677A"]}}},{"name":"OQ627928","node_attrs":{"div":4,"accession":"OQ627928","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"INMI-19442022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"strain_display":{"value":"Italy/OQ627928/2022-09-14"},"date":{"value":"2022-09-14"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["-608T","G610-","T611-","A612-"]}}}]}]}]},{"name":"NODE_0000206","node_attrs":{"div":2,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G42504A"]}},"children":[{"name":"OP324503","node_attrs":{"div":3,"accession":"OP324503","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0189/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP324503/2022-06-27"},"date":{"value":"2022-06-27"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-607T","G149478-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G186537A","-196615A"],"OPG175":["G13-"],"OPG210":["E1728K"]},"labels":{"aa":"OPG175: G13-; OPG210: E1728K"}}},{"name":"OP205098","node_attrs":{"div":4,"accession":"OP205098","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000131"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205098/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C40862T","G95871A"],"OPG116":["E171K"]},"labels":{"aa":"OPG116: E171K"}}},{"name":"OP205076","node_attrs":{"div":2,"accession":"OP205076","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000070"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205076/2022-06-09"},"date":{"value":"2022-06-09"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OP204840","node_attrs":{"div":3,"accession":"OP204840","author":{"author":"Seang,S.,Burrel,S.,Todesco,E.,Leducq,V.,Monsel,G.,Le Pluart,D.,Cordevant,C.,Pourcher,V.,Palich,R.,Charpentier,C.","value":"Seang,S.,Burrel,S.,Todesco,E.,Leducq,V.,Monsel,G.,Le Pluart,D.,Cordevant,C.,Pourcher,V.,Palich,R.,Charpentier,C."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"PatientMPXV"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"APHP Pitie Salpetriere SU, Virology"},"strain_display":{"value":"France/OP204840/2022-06-10"},"date":{"value":"2022-06-10"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G163250A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196612-","A196613-","A196614-"]}}},{"name":"NODE_0000207","node_attrs":{"div":3,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C115870T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}},"children":[{"name":"OP414387","node_attrs":{"div":7,"accession":"OP414387","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0364/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414387/2022-06-26"},"date":{"value":"2022-06-26"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C5292T","G74267A","A161784T","C176852T","G191918A"],"OPG015":["D289N"],"OPG015_dup":["D289N"],"OPG094":["R163Q"]},"labels":{"aa":"OPG015: D289N; OPG015_dup: D289N; OPG094: R163Q"}}},{"name":"OP414335","node_attrs":{"div":7,"accession":"OP414335","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0301/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414335/2022-06-07"},"date":{"value":"2022-06-07"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C1458T","C1920T","G37739A","G61329A","C65828T","G195290A","G195752A"],"OPG001":["D40N"],"OPG001_dup":["D40N"],"OPG002":["D278N"],"OPG002_dup":["D278N"]},"labels":{"aa":"OPG001: D40N; OPG001_dup: D40N; OPG002: D278N; OPG002_dup: D278N"}}}]}]},{"name":"NODE_0000208","node_attrs":{"div":2,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C57173T"]}},"children":[{"name":"OP205099","node_attrs":{"div":4,"accession":"OP205099","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000133"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205099/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["G56365A","A174924T"]}}},{"name":"NODE_0000209","node_attrs":{"div":3,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C142797T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG164":["S7L"]},"labels":{"aa":"OPG164: S7L"}},"children":[{"name":"OP279036","node_attrs":{"div":3,"accession":"OP279036","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-4112/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP279036/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP480404","node_attrs":{"div":5,"accession":"OP480404","author":{"author":"Deanhardt,B.,Miller,M.,Wang,J.R.","value":"Deanhardt,B.,Miller,M.,Wang,J.R."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/USA/NC-UNC-0003/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"University of North Carolina at Chapel Hill, Department of Genetics"},"strain_display":{"value":"USA/OP480404/2022-08-04"},"date":{"value":"2022-08-04"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C74733T","C102889T","A133165-","A133166-","T133167-","C133168-","T133169-","T133170-","T133171-","C133172-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"OQ918697","node_attrs":{"div":11,"accession":"OQ918697","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00486/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ918697/2023-02-18"},"date":{"value":"2023-02-18"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C55036T","G73789A","C96914T","C136435T","G158254A","C166803T","C170381T","G178559A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG073":["E36K"],"OPG094":["G4R"],"OPG117":["S289L"],"OPG192":["P25S"],"OPG198":["S115L"]},"labels":{"aa":"OPG073: E36K; OPG094: G4R; OPG117: S289L; OPG192: P25S; OPG198: S115L"}}},{"name":"OR264396","node_attrs":{"div":8,"accession":"OR264396","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"33_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264396/2022-09-07"},"date":{"value":"2022-09-07"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["G14622A","A28529-","A28530-","T76084-","T76085-","G101241A","T133102-","C136244T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C156446T","G174708A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG025":["R216C"],"OPG044":["K147-"],"OPG153":["R475K"],"OPG204":["M59I"]},"labels":{"aa":"OPG025: R216C; OPG044: K147-; OPG153: R475K; OPG204: M59I"}}},{"name":"OR209323","node_attrs":{"div":4,"accession":"OR209323","author":{"author":"Li,C.M.","value":"Li,C.M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_NC0003"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OR209323/2022-12-XX"},"date":{"value":"2022-12-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T606-","G62268A","A136552-","T136553-","C136554-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","A196614-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OR759200","node_attrs":{"div":3,"accession":"OR759200","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL112/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759200/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"OR759172","node_attrs":{"div":3,"accession":"OR759172","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL084/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759172/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000210","node_attrs":{"div":6,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C30137T","C55072T","G130068A"],"OPG047":["R353K"],"OPG073":["D24N"],"OPG151":["R382Q"]},"labels":{"aa":"OPG047: R353K; OPG073: D24N; OPG151: R382Q"}},"children":[{"name":"OR759178","node_attrs":{"div":7,"accession":"OR759178","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL090/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759178/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["T606-","G26352A","A196614-"],"OPG042":["A249V"]},"labels":{"aa":"OPG042: A249V"}}},{"name":"OR759165","node_attrs":{"div":6,"accession":"OR759165","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL077/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759165/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000211","node_attrs":{"div":1,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G74360A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG094":["R194H"]},"labels":{"aa":"OPG094: R194H","clade":"B.1.1"}},"children":[{"name":"ON792321","node_attrs":{"div":1,"accession":"ON792321","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba6450e/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"strain_display":{"value":"Switzerland/ON792321/2022-06-02"},"date":{"value":"2022-06-02"},"country":{"value":"Switzerland"}},"branch_attrs":{"mutations":{"nuc":["T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","A19360-","T19361-","C19362-","A19363-","T19364-","T19365-","A43653-","T43654-","T43655-","A49176-","A49177-","T49178-","T49179-","T49180-","T49181-","A49182-","T49183-","T49184-","A49185-","A49186-","C49187-","G49188-","G49189-","T49190-","A49191-","A49192-","T49193-","A79063-","A79064-","T79065-","T79066-","T79067-","T79068-","A79069-","A79070-","T79071-","A79072-","T79073-","A79074-","A79075-","T79076-","A79077-","C79078-","T79079-","T79080-","A79081-","A79082-","A79083-","A79084-","A79085-","T79086-","G79087-","G79088-","A79089-","T79090-","G79091-","T79092-","T79093-","G79094-","T79095-","G79096-","T79097-","C79098-","G79099-","T79100-","T79101-","A79102-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A152691-","A152692-","T152693-","G152694-","A152695-","C152696-","G152697-","T152698-","A175944-","T175945-","A175946-","T175947-","C175948-","A175949-","A175950-","C179127A","C179136T","T179138A","T179148-","T179157-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179185A","-179186T","-179187A","-179188T","-179189A","-179190T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T180493-","A180494-","T180495-","C180496-","A180497-","T180498-","T180499-"],"OPG063":["D50-"],"OPG068":["N329-","G330-","N331-","T332-","F333-","I334-"],"OPG205":["I97-","S98-","I99-"]},"labels":{"aa":"OPG063: D50-; OPG068: N329-, G330-, N331-, T332-, F333-, I334-; OPG205: I97-, S98-, I99-"}}},{"name":"ON755236","node_attrs":{"div":1,"accession":"ON755236","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI030"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/ON755236/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"ON755252","node_attrs":{"div":2,"accession":"ON755252","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI046"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/ON755252/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C21530T"],"OPG037":["E302K"]},"labels":{"aa":"OPG037: E302K"}}},{"name":"ON694332","node_attrs":{"div":2,"accession":"ON694332","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON694332/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A163211T","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"ON694329","node_attrs":{"div":1,"accession":"ON694329","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI025"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON694329/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-","A192490-","A192491-","G192492-","T192493-","T192494-","A192495-","G192496-","T192497-","T192498-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP215268","node_attrs":{"div":3,"accession":"OP215268","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI248"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP215268/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C40937T","G175349A"],"OPG204":["S273N"]},"labels":{"aa":"OPG204: S273N"}}},{"name":"OP215223","node_attrs":{"div":1,"accession":"OP215223","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI234"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP215223/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"OP355564","node_attrs":{"div":1,"accession":"OP355564","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI303"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP355564/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","A188351-"]}}},{"name":"OP628448","node_attrs":{"div":3,"accession":"OP628448","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-082531/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP628448/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","G52232A","C119838T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG071":["S736L"]},"labels":{"aa":"OPG071: S736L"}}},{"name":"OP615337","node_attrs":{"div":4,"accession":"OP615337","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI453"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP615337/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C92284T","C116142T","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","G187135A"],"OPG113":["S185L"]},"labels":{"aa":"OPG113: S185L"}}},{"name":"OP555635","node_attrs":{"div":6,"accession":"OP555635","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0564/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555635/2022-09-05"},"date":{"value":"2022-09-05"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C23422T","G54619A","G68997A","C69705T","C156100T"],"OPG039":["E233K"]},"labels":{"aa":"OPG039: E233K"}}},{"name":"OQ547751","node_attrs":{"div":1,"accession":"OQ547751","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI724"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ547751/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OR264399","node_attrs":{"div":3,"accession":"OR264399","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"36_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264399/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","A43500-","T76084-","T76085-","T80846-","T80847-","A89106-","G118500A","T121121-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G160406A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","C196772-","A196773-","T196774-"],"OPG044":["K147-"],"OPG136":["T363M"]},"labels":{"aa":"OPG044: K147-; OPG136: T363M"}}},{"name":"OR264392","node_attrs":{"div":1,"accession":"OR264392","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"31_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264392/2022-08-10"},"date":{"value":"2022-08-10"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OR500079","node_attrs":{"div":6,"accession":"OR500079","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Romania/B-16/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"strain_display":{"value":"Romania/OR500079/2022-08-04"},"date":{"value":"2022-08-04"},"country":{"value":"Romania"}},"branch_attrs":{"mutations":{"nuc":["A31817T","C67289T","G97717T","C133109A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C166374G","T166375G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG085":["E415K"],"OPG117":["E557*"],"OPG191":["L72G"]},"labels":{"aa":"OPG085: E415K; OPG117: E557*; OPG191: L72G"}}},{"name":"OR500080","node_attrs":{"div":10,"accession":"OR500080","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Romania/B-18/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"strain_display":{"value":"Romania/OR500080/2022-08-16"},"date":{"value":"2022-08-16"},"country":{"value":"Romania"}},"branch_attrs":{"mutations":{"nuc":["G17189T","A55140C","T55141A","T75369C","T91506G","G121663A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","T169776C","A173282G","A173284G","T174471A","G179029T","A179046T","A179081T","A179110T","T179121A","C179127T","T179129-","T179130-","T179139A","-179172A","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C179672A","C181209T"],"OPG073":["M1W"],"OPG074":["N662M"],"OPG208":["S136Y"]},"labels":{"aa":"OPG073: M1W; OPG074: N662M; OPG208: S136Y"}}},{"name":"OR500078","node_attrs":{"div":1,"accession":"OR500078","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Romania/B-8/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"strain_display":{"value":"Romania/OR500078/2022-06-29"},"date":{"value":"2022-06-29"},"country":{"value":"Romania"}},"branch_attrs":{"mutations":{"nuc":["T92388-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["F220-"]},"labels":{"aa":"OPG113: F220-"}}},{"name":"OP382479","node_attrs":{"div":1,"accession":"OP382479","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00002"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382479/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON694333","node_attrs":{"div":1,"accession":"ON694333","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON694333/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP310061","node_attrs":{"div":1,"accession":"OP310061","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-088764/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP310061/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"NODE_0000212","node_attrs":{"div":2,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G173429A"]}},"children":[{"name":"ON694334","node_attrs":{"div":2,"accession":"ON694334","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI021"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON694334/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP204857","node_attrs":{"div":3,"accession":"OP204857","author":{"author":"Rhie,G.-E.","value":"Rhie,G.-E."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P1-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OP204857/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["C786T","C71728T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG091":["A120V"]},"labels":{"aa":"OPG091: A120V"}}}]},{"name":"NODE_0000213","node_attrs":{"div":3,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G145305A","G178435A"],"OPG167":["P35S"]},"labels":{"aa":"OPG167: P35S"}},"children":[{"name":"OP555488","node_attrs":{"div":3,"accession":"OP555488","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0392/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555488/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OR030945","node_attrs":{"div":7,"accession":"OR030945","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_34"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR030945/2022-07-19"},"date":{"value":"2022-07-19"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G23288A","C57919T","A74360G","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G183819A"],"OPG077":["R222K"],"OPG094":["H194R"],"OPG210":["D822N"]},"labels":{"aa":"OPG077: R222K; OPG094: H194R; OPG210: D822N"}}}]},{"name":"NODE_0000216","node_attrs":{"div":4,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C17048T","G93828A","G177009A"],"OPG029":["D8N"],"OPG113":["E700K"],"OPG205":["E452K"]},"labels":{"aa":"OPG029: D8N; OPG113: E700K; OPG205: E452K"}},"children":[{"name":"OQ159028","node_attrs":{"div":5,"accession":"OQ159028","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI633"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ159028/2022-11-XX"},"date":{"value":"2022-11-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C41131T"],"OPG060":["E18K"]},"labels":{"aa":"OPG060: E18K"}}},{"name":"OQ339216","node_attrs":{"div":7,"accession":"OQ339216","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI697"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ339216/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G25098A","A28529-","A28530-","T54142A","G111116A","G150551-","T150564-","G150565-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG044":["K147-"],"OPG130":["R263C"]},"labels":{"aa":"OPG044: K147-; OPG130: R263C"}}},{"name":"OQ735077","node_attrs":{"div":11,"accession":"OQ735077","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0626/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OQ735077/2023-03-21"},"date":{"value":"2023-03-21"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-609T","A615-","C616-","C10929T","C22179T","G39515A","G77076A","G129659A","C129949T","G139167A","C196638-","T196639-"],"OPG023":["E658K"],"OPG151":["E246K"]},"labels":{"aa":"OPG023: E658K; OPG151: E246K"}}}]},{"name":"NODE_0000217","node_attrs":{"div":2,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G155698A"]}},"children":[{"name":"OP555659","node_attrs":{"div":7,"accession":"OP555659","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0592/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555659/2022-09-14"},"date":{"value":"2022-09-14"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G685-","T686-","C21910T","C67207T","G81244A","G109451A","G138237A","-196615A"],"OPG037":["R175K"],"OPG085":["R442K"],"OPG105":["R40K"]},"labels":{"aa":"OPG037: R175K; OPG085: R442K; OPG105: R40K"}}},{"name":"NODE_0000218","node_attrs":{"div":3,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G161575A"]}},"children":[{"name":"OP626115","node_attrs":{"div":3,"accession":"OP626115","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI477"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP626115/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"OR459775","node_attrs":{"div":5,"accession":"OR459775","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P002-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459775/2022-09-02"},"date":{"value":"2022-09-02"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["G14640A","C108843T","G136558C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG025":["H210Y"],"OPG153":["I370M"]},"labels":{"aa":"OPG025: H210Y; OPG153: I370M"}}},{"name":"OR086942","node_attrs":{"div":3,"accession":"OR086942","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_133/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR086942/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196748-","T196749-","C196750-"]}}}]}]},{"name":"NODE_0000219","node_attrs":{"div":6,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C46672T","C56805T","C72314T","C103216T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","T152686-","A169769-","C169770-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C180857T"],"OPG066":["E253K"],"OPG074":["M107I"],"OPG092":["D212N"],"OPG123":["V619I"]},"labels":{"aa":"OPG066: E253K; OPG074: M107I; OPG092: D212N; OPG123: V619I"}},"children":[{"name":"OR500083","node_attrs":{"div":8,"accession":"OR500083","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Romania/B-35_L3/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"strain_display":{"value":"Romania/OR500083/2023-02-15"},"date":{"value":"2023-02-15"},"country":{"value":"Romania"}},"branch_attrs":{"mutations":{"nuc":["C9781T","G127563A","-169769A","-169770C"],"OPG149":["R123Q"]},"labels":{"aa":"OPG149: R123Q"}}},{"name":"OR500082","node_attrs":{"div":6,"accession":"OR500082","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Romania/B-35_L2/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"strain_display":{"value":"Romania/OR500082/2023-01-26"},"date":{"value":"2023-01-26"},"country":{"value":"Romania"}},"branch_attrs":{"mutations":{"nuc":["A169771-","G169772-","A169773-","T169774-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"NODE_0000220","node_attrs":{"div":7,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C127628T"],"OPG149":["P145S"]},"labels":{"aa":"OPG149: P145S"}},"children":[{"name":"OR500081","node_attrs":{"div":8,"accession":"OR500081","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Romania/B-35_L1/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"strain_display":{"value":"Romania/OR500081/2023-01-05"},"date":{"value":"2023-01-05"},"country":{"value":"Romania"}},"branch_attrs":{"mutations":{"nuc":["C16327T"]}}},{"name":"NODE_0000221","node_attrs":{"div":8,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C42674T"],"OPG063":["E339K"]},"labels":{"aa":"OPG063: E339K"}},"children":[{"name":"OR500084","node_attrs":{"div":8,"accession":"OR500084","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Romania/B-35_R1/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"strain_display":{"value":"Romania/OR500084/2023-01-05"},"date":{"value":"2023-01-05"},"country":{"value":"Romania"}},"branch_attrs":{"mutations":{"nuc":["A169771-","G169772-","A169773-","T169774-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"OR500085","node_attrs":{"div":8,"accession":"OR500085","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Romania/B-35_R2/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"strain_display":{"value":"Romania/OR500085/2023-01-26"},"date":{"value":"2023-01-26"},"country":{"value":"Romania"}},"branch_attrs":{"mutations":{"nuc":["-169769A","-169770C"]}}},{"name":"OR500086","node_attrs":{"div":10,"accession":"OR500086","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Romania/B-35_R3/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"strain_display":{"value":"Romania/OR500086/2023-02-15"},"date":{"value":"2023-02-15"},"country":{"value":"Romania"}},"branch_attrs":{"mutations":{"nuc":["G169748A","C179190T","T179192A","T179193A","A179198G","C179199-","A179200-","T179201-","A185438C","C185439A"]}}}]}]}]},{"name":"NODE_0000222","node_attrs":{"div":2,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","C29887T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG044":["K147-"]},"labels":{"aa":"OPG044: K147-"}},"children":[{"name":"OR264455","node_attrs":{"div":2,"accession":"OR264455","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"67_D"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264455/2022-08-25"},"date":{"value":"2022-08-25"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-28529A","-28530A","T76084-","T76085-","T80846-","T80847-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-"],"OPG044":["-147K"]},"labels":{"aa":"OPG044: -147K"}}},{"name":"OR264438","node_attrs":{"div":3,"accession":"OR264438","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"56_D"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264438/2022-09-06"},"date":{"value":"2022-09-06"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["T76084-","T76085-","C89382T"]}}},{"name":"OR264437","node_attrs":{"div":2,"accession":"OR264437","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"56_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264437/2022-09-06"},"date":{"value":"2022-09-06"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}},{"name":"OR264439","node_attrs":{"div":2,"accession":"OR264439","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"56_F"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264439/2022-09-06"},"date":{"value":"2022-09-06"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}},{"name":"OR264424","node_attrs":{"div":2,"accession":"OR264424","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"47_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264424/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-28529A","-28530A"],"OPG044":["-147K"]},"labels":{"aa":"OPG044: -147K"}}},{"name":"OR264410","node_attrs":{"div":2,"accession":"OR264410","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"3_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264410/2022-07-29"},"date":{"value":"2022-07-29"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-607T","-28529A","-28530A","-196615A"],"OPG044":["-147K"]},"labels":{"aa":"OPG044: -147K"}}},{"name":"OR264372","node_attrs":{"div":2,"accession":"OR264372","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"19_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264372/2022-08-24"},"date":{"value":"2022-08-24"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["T76084-","T76085-","T80846-","T80847-","A89106-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A152675-","A152676-","A165461-"],"OPG190":["N114-"]},"labels":{"aa":"OPG190: N114-"}}}]},{"name":"NODE_0000223","node_attrs":{"div":2,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C22739T"],"OPG038":["E141K"]},"labels":{"aa":"OPG038: E141K"}},"children":[{"name":"ON808413","node_attrs":{"div":2,"accession":"ON808413","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"CVR_MPXV1a"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"strain_display":{"value":"United Kingdom/ON808413/2022-05-15"},"date":{"value":"2022-05-15"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP355578","node_attrs":{"div":4,"accession":"OP355578","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI322"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP355578/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G55993A","G173727A","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","A188351-"],"OPG074":["S378F"]},"labels":{"aa":"OPG074: S378F"}}},{"name":"OP523990","node_attrs":{"div":7,"accession":"OP523990","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI388"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP523990/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G6376A","G13107A","G117345A","C144256T","G170785A","C190834T"],"OPG016":["S142L"],"OPG024":["S41L"],"OPG136":["S748F"],"OPG198":["E250K"]},"labels":{"aa":"OPG016: S142L; OPG024: S41L; OPG136: S748F; OPG198: E250K"}}},{"name":"OP019276","node_attrs":{"div":2,"accession":"OP019276","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1527495/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP019276/2022-06-21"},"date":{"value":"2022-06-21"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP626111","node_attrs":{"div":2,"accession":"OP626111","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI473"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP626111/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000225","node_attrs":{"div":3,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C86567T"],"OPG108":["E165K"]},"labels":{"aa":"OPG108: E165K"}},"children":[{"name":"OP215272","node_attrs":{"div":5,"accession":"OP215272","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI253"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP215272/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G9245A","G21060A","C174904-","G174905-","T174906-","A174907-","G174908-","G174909-","T174910-","A174911-","T174912-","T174913-","T174914-","A174915-","T174916-","G174917-","T174918-","A174919-","C174920-","C174921-","G174922-","T174923-","A174924-","A174925-","C174926-"],"OPG036":["T2M"],"OPG204":["R125-","R126-","Y127-","L128-","C129-","T130-","V131-","T132-"]},"labels":{"aa":"OPG036: T2M; OPG204: R125-, R126-, Y127-, L128-, C129-, T130-, V131-, T132-"}}},{"name":"OP484684","node_attrs":{"div":3,"accession":"OP484684","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI363"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP484684/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000226","node_attrs":{"div":4,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C22740T","C38937T"],"OPG056":["R33Q"]},"labels":{"aa":"OPG056: R33Q"}},"children":[{"name":"OP555641","node_attrs":{"div":6,"accession":"OP555641","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0570/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555641/2022-09-02"},"date":{"value":"2022-09-02"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G74362A","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","T136555-","A136556-","T136557-","G136558-","A136559-","T136560-","A136561-","T136562-","C136563-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","C177240T"],"OPG094":["A195T"],"OPG153":["I370-","I371-","D372-","D373-","D374-","D375-","D376-","D377-"],"OPG205":["Q529*"]},"labels":{"aa":"OPG094: A195T; OPG153: I370-, I371-, D372-, D373-, D374-, D375-, D376-, D377-; OPG205: Q529*"}}},{"name":"NODE_0000227","node_attrs":{"div":5,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C118523T","A196614-"]}},"children":[{"name":"OP555587","node_attrs":{"div":5,"accession":"OP555587","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0516/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555587/2022-08-17"},"date":{"value":"2022-08-17"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G778-","T779-","A196656-","A196657-"]}}},{"name":"OP555569","node_attrs":{"div":5,"accession":"OP555569","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0494/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555569/2022-08-15"},"date":{"value":"2022-08-15"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000228","node_attrs":{"div":1,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N","clade":"B.1.2"}},"children":[{"name":"ON929079","node_attrs":{"div":1,"accession":"ON929079","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI124"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/ON929079/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"]}}},{"name":"OP331334","node_attrs":{"div":1,"accession":"OP331334","author":{"author":"Grove,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Grove,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000060"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP331334/2022-06-07"},"date":{"value":"2022-06-07"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP415208","node_attrs":{"div":6,"accession":"OP415208","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_Fap1fz_9000234"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415208/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T606-","C24282T","G24622A","C49694T","C92375T","G94221A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG040":["S286L"],"OPG113":["E831K"]},"labels":{"aa":"OPG040: S286L; OPG113: E831K"}}},{"name":"OP415203","node_attrs":{"div":1,"accession":"OP415203","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_fZLVcc_9000228"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415203/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ330980","node_attrs":{"div":5,"accession":"OQ330980","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00363/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ330980/2022-10-07"},"date":{"value":"2022-10-07"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C28321T","C68714T","C94102T","A121162G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"],"OPG113":["T791I"]},"labels":{"aa":"OPG113: T791I"}}},{"name":"OR449688","node_attrs":{"div":2,"accession":"OR449688","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI974"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR449688/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G118391A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"OR449671","node_attrs":{"div":1,"accession":"OR449671","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI957"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR449671/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","C179190-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"OP150927","node_attrs":{"div":1,"accession":"OP150927","author":{"author":"Gigante,C.,Pavlick,J.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y.","value":"Gigante,C.,Pavlick,J.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_WA001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP150927/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035718","node_attrs":{"div":1,"accession":"OR035718","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_112"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035718/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000230","node_attrs":{"div":3,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C3405T","G5375A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","C191835T","G193805A"],"OPG015":["A261V"],"OPG015_dup":["A261V"]},"labels":{"aa":"OPG015: A261V; OPG015_dup: A261V"}},"children":[{"name":"OQ503812","node_attrs":{"div":10,"accession":"OQ503812","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00419/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ503812/2022-11-22"},"date":{"value":"2022-11-22"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C72914T","C112712T","G129749A","G133004A","G154098A","C166171T","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G182486A"],"OPG092":["D12N"],"OPG132":["D277N"],"OPG151":["E276K"],"OPG191":["S4L"]},"labels":{"aa":"OPG092: D12N; OPG132: D277N; OPG151: E276K; OPG191: S4L"}}},{"name":"OR759146","node_attrs":{"div":4,"accession":"OR759146","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL053/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759146/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C170573T","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}}}]},{"name":"NODE_0000231","node_attrs":{"div":12,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A670-","A671-","G2126A","G10224A","T39348C","C64132T","A78942G","T130733C","G138728A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C154736T","A155151C","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","G183791A","T187664C","C195084T","T196774-","A196775-","A196776-"],"OPG002":["S209L"],"OPG002_dup":["S209L"],"OPG021":["R213Q"],"OPG057":["D283G"],"OPG083":["M195I"],"OPG101":["T153A"],"OPG151":["C604R"],"OPG156":["H228Y"],"OPG181":["P109S","E247A"]},"labels":{"aa":"OPG002: S209L; OPG002_dup: S209L; OPG021: R213Q; OPG057: D283G; OPG083: M195I; OPG101: T153A; OPG151: C604R; OPG156: H228Y; OPG181: P109S, E247A"}},"children":[{"name":"OR178742","node_attrs":{"div":12,"accession":"OR178742","author":{"author":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J.","value":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000194/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDPH, VRDL"},"strain_display":{"value":"USA/OR178742/2023-02-14"},"date":{"value":"2023-02-14"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G669-"]}}},{"name":"OR178741","node_attrs":{"div":13,"accession":"OR178741","author":{"author":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J.","value":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000193/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDPH, VRDL"},"strain_display":{"value":"USA/OR178741/2023-02-14"},"date":{"value":"2023-02-14"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-670A","-671A","A31053G","-196774T","-196775A","-196776A"],"OPG047":["C48R"]},"labels":{"aa":"OPG047: C48R"}}}]},{"name":"NODE_0000232","node_attrs":{"div":3,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G143789A","C147168T","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG165":["D92N"],"OPG171":["L61F"]},"labels":{"aa":"OPG165: D92N; OPG171: L61F"}},"children":[{"name":"OP205080","node_attrs":{"div":4,"accession":"OP205080","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000076"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205080/2022-06-09"},"date":{"value":"2022-06-09"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["G61253A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG080":["R256C"]},"labels":{"aa":"OPG080: R256C"}}},{"name":"NODE_0000233","node_attrs":{"div":4,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C20992T"],"OPG036":["D25N"]},"labels":{"aa":"OPG036: D25N"}},"children":[{"name":"OP626125","node_attrs":{"div":5,"accession":"OP626125","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI487"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP626125/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C61780T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"],"OPG080":["R80K"]},"labels":{"aa":"OPG080: R80K"}}},{"name":"OR449692","node_attrs":{"div":6,"accession":"OR449692","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI978"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR449692/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G61253A","G95871A","G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG080":["R256C"],"OPG116":["E171K"],"OPG193":["F263-"]},"labels":{"aa":"OPG080: R256C; OPG116: E171K; OPG193: F263-"}}},{"name":"OR264415","node_attrs":{"div":4,"accession":"OR264415","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"42_F"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264415/2022-06-22"},"date":{"value":"2022-06-22"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OR264412","node_attrs":{"div":4,"accession":"OR264412","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"42_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264412/2022-06-08"},"date":{"value":"2022-06-08"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["C133103T","G133104-","A133105-","A133106-","A133201-","C133202-","C133203-","T133204-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","T196669-","T196670-","T196671-"]}}},{"name":"OR264414","node_attrs":{"div":4,"accession":"OR264414","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"42_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264414/2022-06-22"},"date":{"value":"2022-06-22"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264416","node_attrs":{"div":4,"accession":"OR264416","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"42_G"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264416/2022-06-22"},"date":{"value":"2022-06-22"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OR264413","node_attrs":{"div":4,"accession":"OR264413","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"42_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264413/2022-06-22"},"date":{"value":"2022-06-22"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"NODE_0000236","node_attrs":{"div":5,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C29229T"],"OPG045":["D12N"]},"labels":{"aa":"OPG045: D12N"}},"children":[{"name":"OP205089","node_attrs":{"div":7,"accession":"OP205089","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000101"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205089/2022-06-09"},"date":{"value":"2022-06-09"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["G149561A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G182486A"]}}},{"name":"NODE_0000237","node_attrs":{"div":6,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C57492T","-179194A","-179195T","-179199C","-179200A","-179201T","-179203A","-179205A","-179208C","-179209A","-179210T","-179211T"],"OPG075":["E3K"]},"labels":{"aa":"OPG075: E3K"}},"children":[{"name":"OP205140","node_attrs":{"div":6,"accession":"OP205140","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000193"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205140/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000238","node_attrs":{"div":11,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G10475A","G23462A","G73939A","T147168C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C171808T","-179196A","-179197T","-179198A","-179202T","-179204T","-179206T","-179207A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG094":["D54N"],"OPG171":["F61L"],"OPG199":["S274L"]},"labels":{"aa":"OPG094: D54N; OPG171: F61L; OPG199: S274L"}},"children":[{"name":"OP536807","node_attrs":{"div":11,"accession":"OP536807","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000438"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536807/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OP536763","node_attrs":{"div":11,"accession":"OP536763","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000384"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536763/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}}]}]}]}]}]},{"name":"NODE_0000239","node_attrs":{"div":2,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C188391T"]}},"children":[{"name":"OP215262","node_attrs":{"div":3,"accession":"OP215262","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI238"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP215262/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C179181-","C179190-","G182303A"]}}},{"name":"OP205086","node_attrs":{"div":2,"accession":"OP205086","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000097"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205086/2022-06-06"},"date":{"value":"2022-06-06"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP539914","node_attrs":{"div":2,"accession":"OP539914","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00129/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP539914/2022-09-09"},"date":{"value":"2022-09-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179181-","C179190-","T179244-"]}}},{"name":"OP539909","node_attrs":{"div":2,"accession":"OP539909","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00124/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP539909/2022-09-09"},"date":{"value":"2022-09-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179181-","C179190-","G196753-","G196754-","T196755-"]}}},{"name":"OP536784","node_attrs":{"div":2,"accession":"OP536784","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000408"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536784/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP605583","node_attrs":{"div":7,"accession":"OP605583","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-42-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605583/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["A161-","-607T","C17614A","C27187T","G111484A","G147305A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C159401A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG030":["V74L"],"OPG043":["D257N"],"OPG130":["T140I"],"OPG185":["S162Y"]},"labels":{"aa":"OPG030: V74L; OPG043: D257N; OPG130: T140I; OPG185: S162Y"}}},{"name":"OP879767","node_attrs":{"div":2,"accession":"OP879767","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"NJ-MPXV-054"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"strain_display":{"value":"USA/OP879767/2022-07-25"},"date":{"value":"2022-07-25"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179181-","C179190-"]}}},{"name":"OP687929","node_attrs":{"div":4,"accession":"OP687929","author":{"author":"Gigante,C.M.,Maloney,M.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Morrison,S.S.,Seabolt,M.H.,Weigand,M.R.,Knipe,K.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Pearson,C.,Li,Y.","value":"Gigante,C.M.,Maloney,M.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Morrison,S.S.,Seabolt,M.H.,Weigand,M.R.,Knipe,K.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Pearson,C.,Li,Y."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_CT0004"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP687929/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C22880T","G62253A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG038":["E94K"]},"labels":{"aa":"OPG038: E94K"}}},{"name":"OQ348860","node_attrs":{"div":11,"accession":"OQ348860","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000112/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDPH, VRDL"},"strain_display":{"value":"USA/OQ348860/2022-12-14"},"date":{"value":"2022-12-14"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C7705T","C39334G","G50617A","G62896A","G89947A","C110394T","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","G150753A","A158920T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G183899A"],"OPG057":["A288P"],"OPG070":["D10N"],"OPG082":["S186L"],"OPG110":["E106K"],"OPG129":["R204Q"],"OPG185":["T2S"]},"labels":{"aa":"OPG057: A288P; OPG070: D10N; OPG082: S186L; OPG110: E106K; OPG129: R204Q; OPG185: T2S"}}},{"name":"OQ330997","node_attrs":{"div":6,"accession":"OQ330997","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00390/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ330997/2022-12-14"},"date":{"value":"2022-12-14"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G4248A","C100938T","G146665A","G159103A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C192962T"],"OPG120":["E271K"],"OPG185":["D63N"]},"labels":{"aa":"OPG120: E271K; OPG185: D63N"}}},{"name":"OQ503828","node_attrs":{"div":9,"accession":"OQ503828","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00405/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ503828/2023-01-10"},"date":{"value":"2023-01-10"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A662-","C663-","A664-","G25309A","G28271A","G112785A","T118096C","G133968T","C165231T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179181-","C179190-","C180371T","T196635-","C196636-","T196637-"],"OPG040":["S57L"],"OPG044":["D61N"],"OPG136":["M498V"],"OPG190":["S37L"]},"labels":{"aa":"OPG040: S57L; OPG044: D61N; OPG136: M498V; OPG190: S37L"}}},{"name":"OQ979625","node_attrs":{"div":10,"accession":"OQ979625","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-012937/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OQ979625/2023-01-XX"},"date":{"value":"2023-01-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A63108T","G77907A","G92718A","C136554T","G148238A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C167676T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G180523A","G180531A","G180827A"],"OPG099":["M81I"],"OPG113":["E330K"],"OPG153":["D372N"],"OPG173":["D68N"],"OPG193":["H115Y"],"OPG209":["G5E","E104K"]},"labels":{"aa":"OPG099: M81I; OPG113: E330K; OPG153: D372N; OPG173: D68N; OPG193: H115Y; OPG209: G5E, E104K"}}},{"name":"OQ702779","node_attrs":{"div":4,"accession":"OQ702779","author":{"author":"Gigante,C.,Haydel,D.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salinas,A.,Li,Y.","value":"Gigante,C.,Haydel,D.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salinas,A.,Li,Y."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_LA0009"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ702779/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C85811T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188491T"]}}},{"name":"OQ644778","node_attrs":{"div":3,"accession":"OQ644778","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00472/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ644778/2022-11-10"},"date":{"value":"2022-11-10"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T606-","G23127A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179181-","C179190-","A196614-"]}}},{"name":"OR464207","node_attrs":{"div":6,"accession":"OR464207","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_TX0054"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OR464207/2022-12-XX"},"date":{"value":"2022-12-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T606-","G45781A","G71465A","G96778A","G145287A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG064":["H40Y"],"OPG117":["E244K"],"OPG167":["P41S"]},"labels":{"aa":"OPG064: H40Y; OPG117: E244K; OPG167: P41S"}}},{"name":"NODE_0000240","node_attrs":{"div":4,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A20156G","C170573T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179181-","C179190-"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}},"children":[{"name":"OP597793","node_attrs":{"div":4,"accession":"OP597793","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MN-MDH-MPXV_0019"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Minnesota Department of Health"},"strain_display":{"value":"USA/OP597793/2022-07-20"},"date":{"value":"2022-07-20"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR353582","node_attrs":{"div":5,"accession":"OR353582","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MN-MDH-MPXV_0072"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Minnesota Department of Health, Public Health Laboratory"},"strain_display":{"value":"USA/OR353582/2022-09-07"},"date":{"value":"2022-09-07"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C185818T"],"OPG210":["S1488L"]},"labels":{"aa":"OPG210: S1488L"}}}]},{"name":"NODE_0000241","node_attrs":{"div":7,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T26669C","G96073A","G115235A","C125294T","C135868T","A150586-","T150587-","A150588-","T150589-","A150591-","T150592-","A150595-","T150596-","A150597-","T150598-","A150600-","T150601-"],"OPG117":["D9N"]},"labels":{"aa":"OPG117: D9N"}},"children":[{"name":"OQ159027","node_attrs":{"div":8,"accession":"OQ159027","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI632"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ159027/2022-11-XX"},"date":{"value":"2022-11-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G77052A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C179181-","C179190-"]}}},{"name":"OP959061","node_attrs":{"div":7,"accession":"OP959061","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"BOL-UNIMOL-MPX-293613-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"strain_display":{"value":"Colombia/OP959061/2022-10-11"},"date":{"value":"2022-10-11"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000242","node_attrs":{"div":3,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T157527C","C179181-","C179190-"]}},"children":[{"name":"ON813262","node_attrs":{"div":3,"accession":"ON813262","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI062"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/ON813262/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"OP555483","node_attrs":{"div":4,"accession":"OP555483","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0387/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555483/2022-07-12"},"date":{"value":"2022-07-12"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G154098A"]}}},{"name":"OP689671","node_attrs":{"div":5,"accession":"OP689671","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI518"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP689671/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C34258T","T100218C","G173153A"],"OPG053":["A145T"]},"labels":{"aa":"OPG053: A145T"}}},{"name":"OQ773512","node_attrs":{"div":7,"accession":"OQ773512","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI893"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ773512/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150087A","C156429T","C156509T","G177872A","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}}]},{"name":"NODE_0000243","node_attrs":{"div":6,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G8638A","C21548T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188236T","C188339T"],"OPG037":["D296N"]},"labels":{"aa":"OPG037: D296N"}},"children":[{"name":"OQ503752","node_attrs":{"div":6,"accession":"OQ503752","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-118017/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OQ503752/2022-11-XX"},"date":{"value":"2022-11-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-196615A"]}}},{"name":"NODE_0000244","node_attrs":{"div":8,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C47820T","C68218T"],"OPG085":["R105Q"]},"labels":{"aa":"OPG085: R105Q"}},"children":[{"name":"OR427346","node_attrs":{"div":8,"accession":"OR427346","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-048416/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR427346/2023-04-XX"},"date":{"value":"2023-04-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-"]}}},{"name":"OR427343","node_attrs":{"div":9,"accession":"OR427343","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-038917/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR427343/2023-03-XX"},"date":{"value":"2023-03-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G100939A"]}}},{"name":"OR427340","node_attrs":{"div":8,"accession":"OR427340","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-028603/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR427340/2023-02-XX"},"date":{"value":"2023-02-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR427341","node_attrs":{"div":10,"accession":"OR427341","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-039072/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR427341/2023-03-XX"},"date":{"value":"2023-03-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G156482A","C175867T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG205":["S71F"]},"labels":{"aa":"OPG205: S71F"}}},{"name":"NODE_0000245","node_attrs":{"div":9,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C102741T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG122":["S105L"]},"labels":{"aa":"OPG122: S105L"}},"children":[{"name":"OQ979621","node_attrs":{"div":9,"accession":"OQ979621","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-042823/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OQ979621/2023-04-XX"},"date":{"value":"2023-04-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR499962","node_attrs":{"div":9,"accession":"OR499962","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00505/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499962/2023-04-12"},"date":{"value":"2023-04-12"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499953","node_attrs":{"div":9,"accession":"OR499953","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00496/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499953/2023-04-26"},"date":{"value":"2023-04-26"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000246","node_attrs":{"div":10,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G12239A","G12488A","-196615A"],"OPG023":["S138L","S221F"]},"labels":{"aa":"OPG023: S138L, S221F"}},"children":[{"name":"OQ979624","node_attrs":{"div":10,"accession":"OQ979624","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-028492/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OQ979624/2023-02-XX"},"date":{"value":"2023-02-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR427347","node_attrs":{"div":10,"accession":"OR427347","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-025109/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR427347/2023-02-XX"},"date":{"value":"2023-02-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR427345","node_attrs":{"div":11,"accession":"OR427345","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-036395/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR427345/2023-03-XX"},"date":{"value":"2023-03-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T607-","G12748A","A196615-"]}}}]}]}]}]}]},{"name":"NODE_0000247","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G53326A"]}},"children":[{"name":"NODE_0000248","node_attrs":{"div":6,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A61383C","G63100A","G141114A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G153562A","C177155T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG082":["S118L"],"OPG161":["E5K"],"OPG180":["E291K"]},"labels":{"aa":"OPG082: S118L; OPG161: E5K; OPG180: E291K"}},"children":[{"name":"OP751212","node_attrs":{"div":7,"accession":"OP751212","author":{"author":"Bajwa,M.I.,Miller,H.","value":"Bajwa,M.I.,Miller,H."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"B1118383"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Delaware Public Health Lab, Sequencing/Bioinformatics"},"strain_display":{"value":"USA/OP751212/2022-08-30"},"date":{"value":"2022-08-30"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C136081T"]}}},{"name":"OP751213","node_attrs":{"div":6,"accession":"OP751213","author":{"author":"Bajwa,M.I.,Miller,H.","value":"Bajwa,M.I.,Miller,H."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"B1118385"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Delaware Public Health Lab, Sequencing/Bioinformatics"},"strain_display":{"value":"USA/OP751213/2022-08-30"},"date":{"value":"2022-08-30"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000249","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C121104T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG138":["R10K"]},"labels":{"aa":"OPG138: R10K"}},"children":[{"name":"OR264430","node_attrs":{"div":3,"accession":"OR264430","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"51_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264430/2022-09-05"},"date":{"value":"2022-09-05"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-607T","C15582T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"NODE_0000250","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","T133102-","C134102T","G177009A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG044":["K147-"],"OPG205":["E452K"]},"labels":{"aa":"OPG044: K147-; OPG205: E452K"}},"children":[{"name":"OR264447","node_attrs":{"div":4,"accession":"OR264447","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"63_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264447/2022-08-22"},"date":{"value":"2022-08-22"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["T76084-","T76085-"]}}},{"name":"OR264378","node_attrs":{"div":4,"accession":"OR264378","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"25_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264378/2022-08-22"},"date":{"value":"2022-08-22"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T172087-"]}}}]},{"name":"NODE_0000251","node_attrs":{"div":5,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G57661A","A118917C","C187452T","-196615A"],"OPG077":["S308L"],"OPG136":["I224S"]},"labels":{"aa":"OPG077: S308L; OPG136: I224S"}},"children":[{"name":"OR264457","node_attrs":{"div":6,"accession":"OR264457","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"68_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264457/2022-08-26"},"date":{"value":"2022-08-26"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["T607-","A28529-","A28530-","C62868T","T76084-","T76085-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196615-"],"OPG044":["K147-"]},"labels":{"aa":"OPG044: K147-"}}},{"name":"OR264427","node_attrs":{"div":5,"accession":"OR264427","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"4_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264427/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264394","node_attrs":{"div":5,"accession":"OR264394","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"32_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264394/2022-08-24"},"date":{"value":"2022-08-24"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}}]},{"name":"NODE_0000252","node_attrs":{"div":7,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C7034T","A28529-","A28530-","G70190A","G144895A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G187827A","C190276T"],"OPG044":["K147-"],"OPG089":["E109K"]},"labels":{"aa":"OPG044: K147-; OPG089: E109K"}},"children":[{"name":"OR264452","node_attrs":{"div":7,"accession":"OR264452","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"66_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264452/2022-08-25"},"date":{"value":"2022-08-25"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-"]}}},{"name":"OR264436","node_attrs":{"div":7,"accession":"OR264436","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"55_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264436/2022-08-09"},"date":{"value":"2022-08-09"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-28529A","-28530A","T76084-","T76085-"],"OPG044":["-147K"]},"labels":{"aa":"OPG044: -147K"}}},{"name":"OR264369","node_attrs":{"div":7,"accession":"OR264369","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"16_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264369/2022-08-08"},"date":{"value":"2022-08-08"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000253","node_attrs":{"div":3,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C164385T","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","C187620T"]},"labels":{"clade":"B.1.20"}},"children":[{"name":"OQ320441","node_attrs":{"div":3,"accession":"OQ320441","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_TX0040"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ320441/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","T133102-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179190C","-179199C","-196615A"]}}},{"name":"NODE_0000254","node_attrs":{"div":4,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T602-","T603-","T604-","T605-","T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177398A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196610-","A196611-","A196612-","A196613-","A196614-"]}},"children":[{"name":"OQ918695","node_attrs":{"div":4,"accession":"OQ918695","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00484/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ918695/2023-02-07"},"date":{"value":"2023-02-07"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179190C","-179199C","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR464208","node_attrs":{"div":6,"accession":"OR464208","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_TX0055"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OR464208/2022-12-XX"},"date":{"value":"2022-12-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G129761A","G150577-","A150578-","T150579-","A150580-","T150581-","G150582-","A150583-","T150584-","G150585-","T165597C","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-"],"OPG151":["D280N"],"OPG190":["V159A"]},"labels":{"aa":"OPG151: D280N; OPG190: V159A"}}},{"name":"NODE_0000255","node_attrs":{"div":5,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C177899T","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-"]}},"children":[{"name":"OR500006","node_attrs":{"div":5,"accession":"OR500006","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00530/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR500006/2023-03-24"},"date":{"value":"2023-03-24"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179145T","T179244-"]}}},{"name":"OR499978","node_attrs":{"div":8,"accession":"OR499978","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00521/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499978/2023-05-09"},"date":{"value":"2023-05-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C14016T","C134847T","-179145T","T179244-","C183799T"],"OPG025":["E418K"],"OPG210":["S815L"]},"labels":{"aa":"OPG025: E418K; OPG210: S815L"}}},{"name":"OR499972","node_attrs":{"div":7,"accession":"OR499972","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00515/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499972/2023-04-25"},"date":{"value":"2023-04-25"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G18919A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G187517A"]}}},{"name":"NODE_0000256","node_attrs":{"div":6,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","G115293A"],"OPG133":["A135V"]},"labels":{"aa":"OPG133: A135V"}},"children":[{"name":"OR499966","node_attrs":{"div":6,"accession":"OR499966","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00509/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499966/2023-03-31"},"date":{"value":"2023-03-31"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499965","node_attrs":{"div":6,"accession":"OR499965","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00508/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499965/2023-04-10"},"date":{"value":"2023-04-10"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C193406A"]}}},{"name":"OR499964","node_attrs":{"div":6,"accession":"OR499964","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00507/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499964/2023-04-10"},"date":{"value":"2023-04-10"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000257","node_attrs":{"div":6,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G146690A"],"OPG170":["S30F"]},"labels":{"aa":"OPG170: S30F"}},"children":[{"name":"OR499983","node_attrs":{"div":6,"accession":"OR499983","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00526/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499983/2023-06-09"},"date":{"value":"2023-06-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499951","node_attrs":{"div":6,"accession":"OR499951","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00494/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499951/2023-04-30"},"date":{"value":"2023-04-30"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G196724-","A196725-","G196726-"]}}},{"name":"OR499949","node_attrs":{"div":6,"accession":"OR499949","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00492/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499949/2023-03-30"},"date":{"value":"2023-03-30"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A196713-","T196714-","A196715-"]}}},{"name":"NODE_0000258","node_attrs":{"div":8,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-602T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C159608T","G163900-","A163901-","A163902-","T163903-","C163904-","A163905-","G168964A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A192393C","G192396A","A192402G","-196610A"],"OPG185":["S231F"],"OPG189":["E190-","S191-"]},"labels":{"aa":"OPG185: S231F; OPG189: E190-, S191-"}},"children":[{"name":"OR665165","node_attrs":{"div":9,"accession":"OR665165","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-097301/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR665165/2023-09-XX"},"date":{"value":"2023-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G177918A"],"OPG205":["D755N"]},"labels":{"aa":"OPG205: D755N"}}},{"name":"OR665162","node_attrs":{"div":8,"accession":"OR665162","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-097833/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR665162/2023-09-XX"},"date":{"value":"2023-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000259","node_attrs":{"div":9,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G141131A"]}},"children":[{"name":"OR665164","node_attrs":{"div":9,"accession":"OR665164","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-098659/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR665164/2023-09-XX"},"date":{"value":"2023-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR665163","node_attrs":{"div":10,"accession":"OR665163","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-097798/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR665163/2023-09-XX"},"date":{"value":"2023-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A80466G"],"OPG103":["N156D"]},"labels":{"aa":"OPG103: N156D"}}}]}]}]},{"name":"NODE_0000260","node_attrs":{"div":10,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C15718T","C22349T","C83753T","G98119A","C113363T"],"OPG037":["E29K"],"OPG117":["E691K"],"OPG132":["D60N"]},"labels":{"aa":"OPG037: E29K; OPG117: E691K; OPG132: D60N"}},"children":[{"name":"OR643712","node_attrs":{"div":11,"accession":"OR643712","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00556/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643712/2023-07-31"},"date":{"value":"2023-07-31"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G36246A"]}}},{"name":"OR499987","node_attrs":{"div":10,"accession":"OR499987","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00531/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499987/2023-06-30"},"date":{"value":"2023-06-30"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499975","node_attrs":{"div":10,"accession":"OR499975","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00518/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499975/2023-06-21"},"date":{"value":"2023-06-21"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR473614","node_attrs":{"div":11,"accession":"OR473614","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0077/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR473614/2023-06-27"},"date":{"value":"2023-06-27"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G164230A"],"OPG189":["E300K"]},"labels":{"aa":"OPG189: E300K"}}},{"name":"NODE_0000261","node_attrs":{"div":12,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C23353T","G119341A"],"OPG039":["D256N"],"OPG136":["R83C"]},"labels":{"aa":"OPG039: D256N; OPG136: R83C"}},"children":[{"name":"OR725694","node_attrs":{"div":12,"accession":"OR725694","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0101/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR725694/2023-08-23"},"date":{"value":"2023-08-23"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499995","node_attrs":{"div":12,"accession":"OR499995","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00539/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499995/2023-07-23"},"date":{"value":"2023-07-23"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000262","node_attrs":{"div":13,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C11710T","G41336A","G155611A","T179078-","A179079-","T179080-","A179081-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-"]}},"children":[{"name":"OR643703","node_attrs":{"div":13,"accession":"OR643703","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00561/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643703/2023-08-09"},"date":{"value":"2023-08-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C179082-","C179091-","C179100-","C179109-","C179118-","C179127-","C179136-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000263","node_attrs":{"div":15,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C629-","C630-","A631-","A632-","G633-","A634-","G635-","A636-","G25213A","C168713T","-179078T","-179079A","-179080T","-179081A","-179083A","-179084T","-179085T","-179086A","-179087T","-179088A","-179089T","-179090A","-179092A","-179093T","-179094T","-179095A","-179096T","-179097A","-179098T","-179099A","-179101A","-179102T","-179103T","-179104A","-179105T","-179106A","-179107T","-179108A","-179110A","-179111T","-179112T","-179113A","-179114T","-179115A","-179116T","-179117A","-179119A","-179120T","-179121T","-179122A","-179123T","-179124A","-179125T","-179126A","-179128A","-179129T","-179130T","-179131A","-179132T","-179133A","-179134T","-179135A","-179137A","-179138T","-179139T","-179140A","-179141T","-179142A","-179143T","-179144A","-196610A","-196611A","-196612A","-196613A","-196614A"],"OPG040":["S89F"],"OPG195":["Q162*"]},"labels":{"aa":"OPG040: S89F; OPG195: Q162*"}},"children":[{"name":"OR643710","node_attrs":{"div":16,"accession":"OR643710","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00564/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643710/2023-08-14"},"date":{"value":"2023-08-14"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C170130T"]}}},{"name":"OR643704","node_attrs":{"div":15,"accession":"OR643704","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00562/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643704/2023-08-07"},"date":{"value":"2023-08-07"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000264","node_attrs":{"div":6,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T164946C"]}},"children":[{"name":"OR160416","node_attrs":{"div":10,"accession":"OR160416","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0058/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR160416/2023-05-17"},"date":{"value":"2023-05-17"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G7637A","G36409A","C101983T","G186105A"],"OPG019":["D20N"],"OPG121":["S65L"],"OPG210":["E1584K"]},"labels":{"aa":"OPG019: D20N; OPG121: S65L; OPG210: E1584K"}}},{"name":"NODE_0000265","node_attrs":{"div":7,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C20453T"]}},"children":[{"name":"OR449306","node_attrs":{"div":7,"accession":"OR449306","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/RKI1020"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR449306/2023-07-XX"},"date":{"value":"2023-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-602T","-603T","-604T","-605T","-606T","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"]}}},{"name":"OR421477","node_attrs":{"div":7,"accession":"OR421477","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0019/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR421477/2023-04-20"},"date":{"value":"2023-04-20"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR257451","node_attrs":{"div":7,"accession":"OR257451","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0061/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR257451/2023-05-31"},"date":{"value":"2023-05-31"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR160417","node_attrs":{"div":9,"accession":"OR160417","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0059/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR160417/2023-05-23"},"date":{"value":"2023-05-23"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G43661A","C57550T","A136552-","T136553-","C136554-"],"OPG063":["L10F"],"OPG153":["D385-"]},"labels":{"aa":"OPG063: L10F; OPG153: D385-"}}},{"name":"OR574872","node_attrs":{"div":7,"accession":"OR574872","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0097/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR574872/2023-08-15"},"date":{"value":"2023-08-15"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR643699","node_attrs":{"div":8,"accession":"OR643699","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00550/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643699/2023-07-28"},"date":{"value":"2023-07-28"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G3804T","C193406A"]}}},{"name":"OR574871","node_attrs":{"div":8,"accession":"OR574871","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0096/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR574871/2023-08-10"},"date":{"value":"2023-08-10"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C25865T"]}}},{"name":"OR574862","node_attrs":{"div":7,"accession":"OR574862","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0053/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR574862/2023-05-15"},"date":{"value":"2023-05-15"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR574865","node_attrs":{"div":7,"accession":"OR574865","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0065/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR574865/2023-06-01"},"date":{"value":"2023-06-01"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C169399T"]}}},{"name":"OR574860","node_attrs":{"div":7,"accession":"OR574860","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0051/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR574860/2023-05-12"},"date":{"value":"2023-05-12"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OR574861","node_attrs":{"div":7,"accession":"OR574861","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0052/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR574861/2023-05-13"},"date":{"value":"2023-05-13"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR574870","node_attrs":{"div":12,"accession":"OR574870","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0095/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR574870/2023-08-03"},"date":{"value":"2023-08-03"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G17038A","G34502A","C86402T","G105411A","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","C177946T"],"OPG029":["S11F"],"OPG108":["E220K"],"OPG153":["D384-","D385-"],"OPG205":["T764I"]},"labels":{"aa":"OPG029: S11F; OPG108: E220K; OPG153: D384-, D385-; OPG205: T764I"}}},{"name":"OR499999","node_attrs":{"div":7,"accession":"OR499999","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00543/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499999/2023-06-24"},"date":{"value":"2023-06-24"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR500000","node_attrs":{"div":7,"accession":"OR500000","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00544/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR500000/2023-06-28"},"date":{"value":"2023-06-28"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-"]}}},{"name":"OR500005","node_attrs":{"div":8,"accession":"OR500005","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00549/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR500005/2023-07-26"},"date":{"value":"2023-07-26"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","G18504A","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","-179145T","T179244-"]}}},{"name":"OR499955","node_attrs":{"div":7,"accession":"OR499955","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00498/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499955/2023-04-24"},"date":{"value":"2023-04-24"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499954","node_attrs":{"div":7,"accession":"OR499954","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00497/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499954/2023-04-28"},"date":{"value":"2023-04-28"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499958","node_attrs":{"div":10,"accession":"OR499958","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00501/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499958/2023-05-02"},"date":{"value":"2023-05-02"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A11160G","T126985C","T130733C"],"OPG023":["F581L"],"OPG151":["C604R"]},"labels":{"aa":"OPG023: F581L; OPG151: C604R"}}},{"name":"OR499952","node_attrs":{"div":7,"accession":"OR499952","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00495/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499952/2023-04-26"},"date":{"value":"2023-04-26"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR473618","node_attrs":{"div":8,"accession":"OR473618","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0087/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR473618/2023-07-12"},"date":{"value":"2023-07-12"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C69779T","C196709-","A196710-","A196711-"],"OPG088":["E29K"]},"labels":{"aa":"OPG088: E29K"}}},{"name":"OR473615","node_attrs":{"div":7,"accession":"OR473615","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0083/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR473615/2023-07-10"},"date":{"value":"2023-07-10"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR421479","node_attrs":{"div":7,"accession":"OR421479","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0022/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR421479/2023-05-04"},"date":{"value":"2023-05-04"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR160415","node_attrs":{"div":7,"accession":"OR160415","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0057/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR160415/2023-05-18"},"date":{"value":"2023-05-18"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR421480","node_attrs":{"div":7,"accession":"OR421480","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0023/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR421480/2023-05-07"},"date":{"value":"2023-05-07"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR421478","node_attrs":{"div":7,"accession":"OR421478","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0020/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR421478/2023-04-27"},"date":{"value":"2023-04-27"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000266","node_attrs":{"div":8,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C2313T","G194897A"],"OPG002":["D147N"],"OPG002_dup":["D147N"]},"labels":{"aa":"OPG002: D147N; OPG002_dup: D147N"}},"children":[{"name":"OR500001","node_attrs":{"div":8,"accession":"OR500001","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00545/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR500001/2023-06-10"},"date":{"value":"2023-06-10"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499998","node_attrs":{"div":9,"accession":"OR499998","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00542/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499998/2023-06-22"},"date":{"value":"2023-06-22"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G51378A","T196676-","G196677-","T196678-"]}}}]},{"name":"NODE_0000270","node_attrs":{"div":8,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C180618T"],"OPG209":["S34L"]},"labels":{"aa":"OPG209: S34L"}},"children":[{"name":"OR421481","node_attrs":{"div":9,"accession":"OR421481","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0067/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR421481/2023-06-08"},"date":{"value":"2023-06-08"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C98128T"],"OPG117":["P694S"]},"labels":{"aa":"OPG117: P694S"}}},{"name":"OR353590","node_attrs":{"div":9,"accession":"OR353590","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MN-MDH-MPXV_0080"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Minnesota Department of Health, Public Health Laboratory"},"strain_display":{"value":"USA/OR353590/2023-06-05"},"date":{"value":"2023-06-05"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C134847T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T194619C"],"OPG002_dup":["F54S"]},"labels":{"aa":"OPG002_dup: F54S"}}},{"name":"OR473622","node_attrs":{"div":8,"accession":"OR473622","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0076/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR473622/2023-06-27"},"date":{"value":"2023-06-27"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR473620","node_attrs":{"div":8,"accession":"OR473620","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0074/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR473620/2023-06-22"},"date":{"value":"2023-06-22"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR473619","node_attrs":{"div":10,"accession":"OR473619","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0088/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR473619/2023-07-17"},"date":{"value":"2023-07-17"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C61724T","C111728T"],"OPG080":["E99K"],"OPG130":["D59N"]},"labels":{"aa":"OPG080: E99K; OPG130: D59N"}}},{"name":"NODE_0000271","node_attrs":{"div":9,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-604T","-605T","-606T","C174050T"]}},"children":[{"name":"OR725692","node_attrs":{"div":9,"accession":"OR725692","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0098/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR725692/2023-08-19"},"date":{"value":"2023-08-19"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G635-","A636-","A637-"]}}},{"name":"OR502626","node_attrs":{"div":13,"accession":"OR502626","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0091/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR502626/2023-07-23"},"date":{"value":"2023-07-23"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C5912T","C25865T","C56140T","C175358T","G191298A"],"OPG015":["R82K"],"OPG015_dup":["R82K"],"OPG074":["R329K"],"OPG204":["S276L"]},"labels":{"aa":"OPG015: R82K; OPG015_dup: R82K; OPG074: R329K; OPG204: S276L"}}},{"name":"OR473617","node_attrs":{"div":9,"accession":"OR473617","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0085/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR473617/2023-07-11"},"date":{"value":"2023-07-11"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000272","node_attrs":{"div":11,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","G113508A","C136791T"],"OPG153":["E293K"]},"labels":{"aa":"OPG153: E293K"}},"children":[{"name":"OR725697","node_attrs":{"div":11,"accession":"OR725697","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0107/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR725697/2023-09-06"},"date":{"value":"2023-09-06"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR725696","node_attrs":{"div":11,"accession":"OR725696","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0106/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR725696/2023-09-05"},"date":{"value":"2023-09-05"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000273","node_attrs":{"div":10,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C105798T"]}},"children":[{"name":"OR502625","node_attrs":{"div":10,"accession":"OR502625","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0090/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR502625/2023-07-21"},"date":{"value":"2023-07-21"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000274","node_attrs":{"div":11,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G148126A","T196633-","C196634-","T196635-"]}},"children":[{"name":"OR725698","node_attrs":{"div":11,"accession":"OR725698","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-052-0100/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR725698/2023-08-22"},"date":{"value":"2023-08-22"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR725693","node_attrs":{"div":11,"accession":"OR725693","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0099/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR725693/2023-08-18"},"date":{"value":"2023-08-18"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]}]}]}]}]}]}]}]}]}]},{"name":"NODE_0000275","node_attrs":{"div":1,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G190660A"],"OPG016":["R84K"]},"labels":{"aa":"OPG016: R84K","clade":"B.1.3"}},"children":[{"name":"ON983168","node_attrs":{"div":1,"accession":"ON983168","author":{"author":"Chmel,M.,Pajer,P.,Nagy,A.,Zlamal,M.,Jirincova,H.,Dresler,J.,Bartos,O.","value":"Chmel,M.,Pajer,P.,Nagy,A.,Zlamal,M.,Jirincova,H.,Dresler,J.,Bartos,O."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPxV/Prague_001/2022/flye_medaka"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Military Heatlh Institute, Military Heatlh Institute in Prague"},"strain_display":{"value":"Czech Republic/ON983168/2022-04-28"},"date":{"value":"2022-04-28"},"country":{"value":"Czech Republic"}},"branch_attrs":{"mutations":{"nuc":["T80849-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP414383","node_attrs":{"div":1,"accession":"OP414383","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0356/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414383/2022-05-23"},"date":{"value":"2022-05-23"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["A666-","T667-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OQ721953","node_attrs":{"div":9,"accession":"OQ721953","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Taiwan/110-525030/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"strain_display":{"value":"Taiwan/OQ721953/2023-03-XX"},"date":{"value":"2023-03-XX"},"country":{"value":"Taiwan"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","C64426T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C166940T","T177665A","A177666T","A177667T","G178104T","G178290T","T178629A","G196412A"],"OPG205":["N670K","N671F"]},"labels":{"aa":"OPG205: N670K, N671F"}}},{"name":"NODE_0000276","node_attrs":{"div":6,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C17196T","C39898T","C148933T","G171318A","C175241T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG057":["D100N"],"OPG174":["E155K"],"OPG199":["E111K"],"OPG204":["S237L"]},"labels":{"aa":"OPG057: D100N; OPG174: E155K; OPG199: E111K; OPG204: S237L"}},"children":[{"name":"OP205116","node_attrs":{"div":6,"accession":"OP205116","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000158"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205116/2022-07-07"},"date":{"value":"2022-07-07"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OP536780","node_attrs":{"div":6,"accession":"OP536780","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000404"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536780/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T606-","A62041-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"]}}}]},{"name":"NODE_0000277","node_attrs":{"div":2,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G55133A"],"OPG074":["R665C"]},"labels":{"aa":"OPG074: R665C"}},"children":[{"name":"OQ581854","node_attrs":{"div":4,"accession":"OQ581854","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Taiwan/109-005210/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"strain_display":{"value":"Taiwan/OQ581854/2023-02-XX"},"date":{"value":"2023-02-XX"},"country":{"value":"Taiwan"}},"branch_attrs":{"mutations":{"nuc":["G152776A","G158406A","A192404-","G192405-","T192406-","A192411-"],"OPG180":["D29N"]},"labels":{"aa":"OPG180: D29N"}}},{"name":"NODE_0000278","node_attrs":{"div":3,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C64426T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"ON792320","node_attrs":{"div":4,"accession":"ON792320","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba6449f/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"strain_display":{"value":"Switzerland/ON792320/2022-06-01"},"date":{"value":"2022-06-01"},"country":{"value":"Switzerland"}},"branch_attrs":{"mutations":{"nuc":["G159376A"],"OPG185":["D154N"]},"labels":{"aa":"OPG185: D154N"}}},{"name":"ON782054","node_attrs":{"div":5,"accession":"ON782054","author":{"author":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0001a/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"strain_display":{"value":"Spain/ON782054/2022-05-31"},"date":{"value":"2022-05-31"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["G50337A","A122238T","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A169759G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A193392G","T193688C","T194099C","T194619C","T195948C","-196615A"],"OPG001_dup":["L105S"],"OPG002_dup":["F54S"],"OPG003_dup":["N264D"],"OPG069":["G118R"],"OPG143":["S360T"]},"labels":{"aa":"OPG001_dup: L105S; OPG002_dup: F54S; OPG003_dup: N264D; OPG069: G118R; OPG143: S360T"}}},{"name":"ON782055","node_attrs":{"div":5,"accession":"ON782055","author":{"author":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0001b/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"strain_display":{"value":"Spain/ON782055/2022-05-31"},"date":{"value":"2022-05-31"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["A48265T","C48296G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG068":["D22V"]},"labels":{"aa":"OPG068: D22V"}}},{"name":"ON782021","node_attrs":{"div":3,"accession":"ON782021","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX-37/Finland/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"strain_display":{"value":"Finland/ON782021/2022-05-24"},"date":{"value":"2022-05-24"},"country":{"value":"Finland"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"ON622722","node_attrs":{"div":4,"accession":"ON622722","lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_FR_HCL0001_2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Virology, GENomique EPIdemiologique das maladies Infectieuses, France"},"strain_display":{"value":"France/ON622722/2022-05-22"},"date":{"value":"2022-05-22"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["C109627A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG129":["A460S"]},"labels":{"aa":"OPG129: A460S"}}},{"name":"OP215273","node_attrs":{"div":5,"accession":"OP215273","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI251"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP215273/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G5515A","T54004C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C179259T","C191695T"]}}},{"name":"OP205067","node_attrs":{"div":3,"accession":"OP205067","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000061"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205067/2022-05-27"},"date":{"value":"2022-05-27"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-607T","-196615A"]}}},{"name":"OP415255","node_attrs":{"div":3,"accession":"OP415255","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_GZUtx9_9000301"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415255/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T606-","A196614-"]}}},{"name":"OP536751","node_attrs":{"div":4,"accession":"OP536751","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000370"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536751/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C158422T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"]}}},{"name":"OP605568","node_attrs":{"div":6,"accession":"OP605568","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-26-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605568/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["C12426T","C44716T","C141194T","A196614-"],"OPG023":["E159K"],"OPG064":["E395K"]},"labels":{"aa":"OPG023: E159K; OPG064: E395K"}}},{"name":"OP555633","node_attrs":{"div":4,"accession":"OP555633","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0562/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555633/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168066T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG153":["D385-"],"OPG193":["Q245*"]},"labels":{"aa":"OPG153: D385-; OPG193: Q245*"}}},{"name":"OQ054224","node_attrs":{"div":4,"accession":"OQ054224","author":{"author":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_IL0030"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ054224/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G108819A","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OR035732","node_attrs":{"div":4,"accession":"OR035732","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_126"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035732/2022-10-03"},"date":{"value":"2022-10-03"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G92135A","T133102-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OR353547","node_attrs":{"div":3,"accession":"OR353547","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MN-MDH-MPXV_0037"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Minnesota Department of Health, Public Health Laboratory"},"strain_display":{"value":"USA/OR353547/2022-08-03"},"date":{"value":"2022-08-03"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","T150567-","G150568-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OR134560","node_attrs":{"div":14,"accession":"OR134560","author":{"author":"Miller,H.,Bajwa,M.","value":"Miller,H.,Bajwa,M."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"B1221136"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Delaware Public Health Lab, Sequencing/Bioinformatics"},"strain_display":{"value":"USA/OR134560/2023-03-13"},"date":{"value":"2023-03-13"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C19558T","G32277A","C35688T","G39140A","G55059A","G75512A","C110402T","C121161T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C170673T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C179542T","C189174T"],"OPG034":["E150K"],"OPG049":["S292L"],"OPG073":["S28L"],"OPG095":["R237K"],"OPG139":["A70T"]},"labels":{"aa":"OPG034: E150K; OPG049: S292L; OPG073: S28L; OPG095: R237K; OPG139: A70T"}}},{"name":"OX248696","node_attrs":{"div":5,"accession":"OX248696","lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX248696/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{"nuc":["T606-","G37250A","C138080T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A196614-"],"OPG155":["E138K"]},"labels":{"aa":"OPG155: E138K"}}},{"name":"OR759179","node_attrs":{"div":5,"accession":"OR759179","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL091/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759179/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["G85581A","C122502T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG107":["V24I"],"OPG143":["D272N"]},"labels":{"aa":"OPG107: V24I; OPG143: D272N"}}},{"name":"ON754985","node_attrs":{"div":3,"accession":"ON754985","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_SI2022_S4"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/ON754985/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["A33-","T157-","-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OP605552","node_attrs":{"div":3,"accession":"OP605552","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-09-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605552/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["T38-","T157-","-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"ON754986","node_attrs":{"div":3,"accession":"ON754986","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_SI2022_S5"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/ON754986/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["A161-","-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"ON754984","node_attrs":{"div":3,"accession":"ON754984","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_SI2022_S3"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/ON754984/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["A240-","-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"ON838178","node_attrs":{"div":3,"accession":"ON838178","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"SI2022_S7"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/ON838178/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["A33-","T157-","-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"]}}},{"name":"OP605551","node_attrs":{"div":3,"accession":"OP605551","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-08-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605551/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["A33-","T157-","-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"NODE_0000279","node_attrs":{"div":4,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A33-","T157-","-607T","G167517A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG193":["E62K"]},"labels":{"aa":"OPG193: E62K"}},"children":[{"name":"ON754987","node_attrs":{"div":4,"accession":"ON754987","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_SI2022_S1_VEROE6"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/ON754987/2022-05-23"},"date":{"value":"2022-05-23"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{}}},{"name":"ON609725","node_attrs":{"div":4,"accession":"ON609725","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Skubic,C.,Rozman,D.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Skubic,C.,Rozman,D.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"SLO"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia"},"strain_display":{"value":"Slovenia/ON609725/2022-05-23"},"date":{"value":"2022-05-23"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000280","node_attrs":{"div":8,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","G72609A","G72610T","G72611T","T72614A","A72617C","A72977-","A72978-","T72979-","G72980-","A72981-"],"OPG092":["C111G","K112*","P113N","T114S"]},"labels":{"aa":"OPG092: C111G, K112*, P113N, T114S"}},"children":[{"name":"OP605560","node_attrs":{"div":12,"accession":"OP605560","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-18-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605560/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["G19153A","A55133G","T64426C","G183650A"],"OPG074":["C665R"],"OPG210":["M765I"]},"labels":{"aa":"OPG074: C665R; OPG210: M765I"}}},{"name":"OP605562","node_attrs":{"div":9,"accession":"OP605562","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-20-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605562/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["A29748T"],"OPG047":["*483K"]},"labels":{"aa":"OPG047: *483K"}}}]},{"name":"NODE_0000281","node_attrs":{"div":15,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C15969T","C17998T","G40610A","C43803T","C63879T","G70190A","G118289A","C147011T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G152776A","C159532T","G161629A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C189427T"],"OPG005":["P77S"],"OPG027":["E137K"],"OPG031":["M277I"],"OPG064":["G699E"],"OPG083":["D280N"],"OPG089":["E109K"],"OPG180":["D29N"],"OPG185":["P206S"],"OPG188":["E12K"]},"labels":{"aa":"OPG005: P77S; OPG027: E137K; OPG031: M277I; OPG064: G699E; OPG083: D280N; OPG089: E109K; OPG180: D29N; OPG185: P206S; OPG188: E12K"}},"children":[{"name":"OQ451904","node_attrs":{"div":15,"accession":"OQ451904","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/RKI719"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ451904/2023-01-XX"},"date":{"value":"2023-01-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"OQ451903","node_attrs":{"div":15,"accession":"OQ451903","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/RKI718"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ451903/2023-01-XX"},"date":{"value":"2023-01-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000282","node_attrs":{"div":6,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C8612T","C56018T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G187156A"],"OPG074":["E370K"]},"labels":{"aa":"OPG074: E370K"}},"children":[{"name":"OP605570","node_attrs":{"div":6,"accession":"OP605570","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-28-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605570/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000283","node_attrs":{"div":7,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G52232A"],"OPG071":["S736L"]},"labels":{"aa":"OPG071: S736L"}},"children":[{"name":"OP605585","node_attrs":{"div":7,"accession":"OP605585","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-44-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605585/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{}}},{"name":"OP605581","node_attrs":{"div":7,"accession":"OP605581","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-40-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605581/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["A204-"]}}},{"name":"OP605578","node_attrs":{"div":10,"accession":"OP605578","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-36-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605578/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["T163-","C64583A","C115217T","C183631T"],"OPG083":["G45V"],"OPG210":["S759F"]},"labels":{"aa":"OPG083: G45V; OPG210: S759F"}}}]}]},{"name":"NODE_0000289","node_attrs":{"div":4,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G105923A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG124":["L16F"]},"labels":{"aa":"OPG124: L16F","clade":"C.1"}},"children":[{"name":"LC753969","node_attrs":{"div":4,"accession":"LC753969","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220176"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC753969/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{}}},{"name":"OR035728","node_attrs":{"div":5,"accession":"OR035728","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_122"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035728/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G149818A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG176":["D4N"]},"labels":{"aa":"OPG176: D4N"}}},{"name":"OQ581853","node_attrs":{"div":6,"accession":"OQ581853","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Taiwan/110-093831/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"strain_display":{"value":"Taiwan/OQ581853/2023-02-XX"},"date":{"value":"2023-02-XX"},"country":{"value":"Taiwan"}},"branch_attrs":{"mutations":{"nuc":["T132513C","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C185069T"]}}},{"name":"LC753970","node_attrs":{"div":4,"accession":"LC753970","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220187"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC753970/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{}}},{"name":"LC753968","node_attrs":{"div":4,"accession":"LC753968","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220165"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC753968/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000291","node_attrs":{"div":5,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C3987T"]}},"children":[{"name":"OQ721954","node_attrs":{"div":10,"accession":"OQ721954","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Taiwan/110-539498/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"strain_display":{"value":"Taiwan/OQ721954/2023-03-XX"},"date":{"value":"2023-03-XX"},"country":{"value":"Taiwan"}},"branch_attrs":{"mutations":{"nuc":["-607T","C798T","C11923T","T14737C","C48442T","G90825A","G102694A","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A191312G","G196412A"],"OPG015_dup":["I87V"],"OPG068":["A81V"]},"labels":{"aa":"OPG015_dup: I87V; OPG068: A81V"}}},{"name":"OQ581855","node_attrs":{"div":8,"accession":"OQ581855","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Taiwan/0310000009/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"strain_display":{"value":"Taiwan/OQ581855/2023-03-XX"},"date":{"value":"2023-03-XX"},"country":{"value":"Taiwan"}},"branch_attrs":{"mutations":{"nuc":["G15797A","C41168T","A137251T"]}}}]},{"name":"NODE_0000292","node_attrs":{"div":5,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C166940T","G193223A"]}},"children":[{"name":"OQ721952","node_attrs":{"div":12,"accession":"OQ721952","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Taiwan/240031000030/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"strain_display":{"value":"Taiwan/OQ721952/2023-03-XX"},"date":{"value":"2023-03-XX"},"country":{"value":"Taiwan"}},"branch_attrs":{"mutations":{"nuc":["C798T","C13503T","G33539A","G34948A","G40174A","G156025A","A183935G","A184219G"],"OPG025":["A589T"],"OPG054":["A350V"],"OPG057":["P8S"],"OPG210":["I860M","Y955C"]},"labels":{"aa":"OPG025: A589T; OPG054: A350V; OPG057: P8S; OPG210: I860M, Y955C"}}},{"name":"NODE_0000293","node_attrs":{"div":6,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C3987T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"LC760460","node_attrs":{"div":8,"accession":"LC760460","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220304"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC760460/2023-01-23"},"date":{"value":"2023-01-23"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{"nuc":["G48887A","G75699A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG096":["R38Q"]},"labels":{"aa":"OPG096: R38Q"}}},{"name":"LC760461","node_attrs":{"div":7,"accession":"LC760461","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220343"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC760461/2023-02-13"},"date":{"value":"2023-02-13"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{"nuc":["C798T","C68765T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G196412A"],"OPG086":["M33I"]},"labels":{"aa":"OPG086: M33I"}}},{"name":"LC756924","node_attrs":{"div":7,"accession":"LC756924","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220325"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC756924/2023-01-30"},"date":{"value":"2023-01-30"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{"nuc":["C151434T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"LC756923","node_attrs":{"div":6,"accession":"LC756923","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220318"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC756923/2023-01-25"},"date":{"value":"2023-01-25"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{"nuc":["C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"LC756925","node_attrs":{"div":7,"accession":"LC756925","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220342"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC756925/2023-02-09"},"date":{"value":"2023-02-09"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{"nuc":["C84734T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OR459782","node_attrs":{"div":8,"accession":"OR459782","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P009-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459782/2023-04-12"},"date":{"value":"2023-04-12"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["G12908A","C159231T","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C"]}}},{"name":"OR665166","node_attrs":{"div":11,"accession":"OR665166","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-092809/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR665166/2023-09-XX"},"date":{"value":"2023-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T606-","G13434A","G29650A","C33332T","G37974A","C74691T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179181C","-179226C","A196614-"],"OPG025":["R612C"],"OPG046":["T27I"],"OPG050":["R26Q"],"OPG056":["S354L"]},"labels":{"aa":"OPG025: R612C; OPG046: T27I; OPG050: R26Q; OPG056: S354L"}}},{"name":"OR459804","node_attrs":{"div":7,"accession":"OR459804","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P034-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459804/2023-04-25"},"date":{"value":"2023-04-25"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G163603A","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C"],"OPG189":["D91N"]},"labels":{"aa":"OPG189: D91N"}}},{"name":"OR459798","node_attrs":{"div":7,"accession":"OR459798","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P027-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459798/2023-04-22"},"date":{"value":"2023-04-22"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["G5173A","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","C192037T"]}}},{"name":"OR459797","node_attrs":{"div":6,"accession":"OR459797","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P026-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459797/2023-04-22"},"date":{"value":"2023-04-22"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["A113921-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","T169716C","G169717A","T169721A","G169775A","T169776C","A169780T","-179181T","-179226T"],"OPG197":["M16T","S18T","V36T","E37D"]},"labels":{"aa":"OPG197: M16T, S18T, V36T, E37D"}}},{"name":"OR459796","node_attrs":{"div":8,"accession":"OR459796","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P024-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459796/2023-04-21"},"date":{"value":"2023-04-21"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["T606-","G57129A","G144095A","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","A196614-"],"OPG165":["D194N"]},"labels":{"aa":"OPG165: D194N"}}},{"name":"OR459793","node_attrs":{"div":6,"accession":"OR459793","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P020-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459793/2023-04-19"},"date":{"value":"2023-04-19"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C"]}}},{"name":"LC756922","node_attrs":{"div":6,"accession":"LC756922","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220310"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC756922/2023-01-25"},"date":{"value":"2023-01-25"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{"nuc":["C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OR459783","node_attrs":{"div":6,"accession":"OR459783","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P010-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459783/2023-04-13"},"date":{"value":"2023-04-13"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C"]}}},{"name":"NODE_0000294","node_attrs":{"div":7,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C155209T","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","A196614-"]}},"children":[{"name":"OR459780","node_attrs":{"div":7,"accession":"OR459780","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P007-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459780/2023-04-10"},"date":{"value":"2023-04-10"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{}}},{"name":"OR459789","node_attrs":{"div":7,"accession":"OR459789","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P016-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459789/2023-04-18"},"date":{"value":"2023-04-18"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000297","node_attrs":{"div":7,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C52108T","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C"]}},"children":[{"name":"OR459784","node_attrs":{"div":8,"accession":"OR459784","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P011-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459784/2023-04-14"},"date":{"value":"2023-04-14"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["C97608T"]}}},{"name":"OR459800","node_attrs":{"div":7,"accession":"OR459800","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P029-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459800/2023-04-23"},"date":{"value":"2023-04-23"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{}}},{"name":"OR459794","node_attrs":{"div":8,"accession":"OR459794","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P021-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459794/2023-04-21"},"date":{"value":"2023-04-21"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["T178915C"]}}},{"name":"OR459802","node_attrs":{"div":7,"accession":"OR459802","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P032-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459802/2023-04-25"},"date":{"value":"2023-04-25"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{}}},{"name":"OR459792","node_attrs":{"div":7,"accession":"OR459792","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P019-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459792/2023-04-19"},"date":{"value":"2023-04-19"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000299","node_attrs":{"div":8,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C149963T","G184562A"],"OPG176":["S52L"]},"labels":{"aa":"OPG176: S52L"}},"children":[{"name":"OR459778","node_attrs":{"div":9,"accession":"OR459778","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P005-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459778/2023-03-13"},"date":{"value":"2023-03-13"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["G85691A","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C"]}}},{"name":"NODE_0000300","node_attrs":{"div":13,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C21062T","G101241A","G152866A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G188348A","C188946T","C191053-","A191054-","T191055-","G191056-","G191057-","A191058-","G191059-","T191060-","C191061-","G191062-","G191063-","T191064-","A191065-","G191066-","A191067-","T191068-","T191069-","T191070-","C191071-","A191072-","T191073-","G191074-","G191075-","C191076-","T191077-","G191078-","T191079-","C191080-","G191081-","A191082-","T191083-","G191084-","A191085-","G191086-","C191087-","A191088-","G191089-","T191090-","T191091-","T191092-","C191093-","A191094-","C191095-","G191096-","A191097-","C191098-","G191099-","A191100-","C191101-","C191102-","T191103-","C191104-","G191105-","A191106-","T191107-","C191108-","T191109-","T191110-","T191111-","G191112-","G191113-","T191114-","C191115-","A191116-","T191117-","T191118-","A191119-","T191120-","C191121-","T191122-","T191123-","T191124-","G191125-","G191126-","T191127-","A191128-","G191129-"],"OPG036":["M1I"],"OPG180":["D59N"]},"labels":{"aa":"OPG036: M1I; OPG180: D59N"}},"children":[{"name":"OR643705","node_attrs":{"div":21,"accession":"OR643705","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00563/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643705/2023-08-16"},"date":{"value":"2023-08-16"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G21880A","G47532A","A101241G","C125074T","G133704A","G133838A","A152866G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T180483A","-191053C","-191054A","-191055T","-191056G","-191057G","-191058A","-191059G","-191060T","-191061C","-191062G","-191063G","-191064T","-191065A","-191066G","-191067A","-191068T","-191069T","-191070T","-191071C","-191072A","-191073T","-191074G","-191075G","-191076C","-191077T","-191078G","-191079T","-191080C","-191081G","-191082A","-191083T","-191084G","-191085A","-191086G","-191087C","-191088A","-191089G","-191090T","-191091T","-191092T","-191093C","-191094A","-191095C","-191096G","-191097A","-191098C","-191099G","-191100A","-191101C","-191102C","-191103T","-191104C","-191105G","-191106A","-191107T","-191108C","-191109T","-191110T","-191111T","-191112G","-191113G","-191114T","-191115C","-191116A","-191117T","-191118T","-191119A","-191120T","-191121C","-191122T","-191123T","-191124T","-191125G","-191126G","-191127T","-191128A","-191129G"],"OPG037":["S185F"],"OPG180":["N59D"]},"labels":{"aa":"OPG037: S185F; OPG180: N59D"}}},{"name":"NODE_0000301","node_attrs":{"div":14,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C142797T"],"OPG164":["S7L"]},"labels":{"aa":"OPG164: S7L"}},"children":[{"name":"OR381841","node_attrs":{"div":14,"accession":"OR381841","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0645/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381841/2023-07-07"},"date":{"value":"2023-07-07"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OR326996","node_attrs":{"div":14,"accession":"OR326996","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0632/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR326996/2023-06-25"},"date":{"value":"2023-06-25"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T591A","-607T","-608T","-609T","A196619T"]}}},{"name":"OR326992","node_attrs":{"div":14,"accession":"OR326992","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0628/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR326992/2023-06-16"},"date":{"value":"2023-06-16"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179183T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-"]}}},{"name":"OR326991","node_attrs":{"div":15,"accession":"OR326991","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0627/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR326991/2023-06-15"},"date":{"value":"2023-06-15"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G165862T"]}}},{"name":"OR519724","node_attrs":{"div":14,"accession":"OR519724","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR519724/2023-08-XX"},"date":{"value":"2023-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"]}}},{"name":"OR487998","node_attrs":{"div":15,"accession":"OR487998","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0680/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487998/2023-08-08"},"date":{"value":"2023-08-08"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["A176268G"],"OPG205":["S205G"]},"labels":{"aa":"OPG205: S205G"}}},{"name":"OR487990","node_attrs":{"div":14,"accession":"OR487990","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0669/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487990/2023-08-01"},"date":{"value":"2023-08-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OR487991","node_attrs":{"div":15,"accession":"OR487991","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0671/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487991/2023-08-02"},"date":{"value":"2023-08-02"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C165219T"],"OPG190":["S33F"]},"labels":{"aa":"OPG190: S33F"}}},{"name":"OR487989","node_attrs":{"div":15,"accession":"OR487989","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0668/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487989/2023-08-01"},"date":{"value":"2023-08-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G90093A"]}}},{"name":"OR487986","node_attrs":{"div":15,"accession":"OR487986","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0665/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487986/2023-08-01"},"date":{"value":"2023-08-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C72039T"]}}},{"name":"NODE_0000302_NODE_0000303_merged","node_attrs":{"div":16,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T57476C"],"OPG075":["Q8R"]},"labels":{"aa":"OPG075: Q8R"}},"children":[{"name":"OR487995","node_attrs":{"div":17,"accession":"OR487995","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0675/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487995/2023-08-03"},"date":{"value":"2023-08-03"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C175864T"],"OPG205":["S70L"]},"labels":{"aa":"OPG205: S70L"}}},{"name":"OR487996","node_attrs":{"div":16,"accession":"OR487996","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0677/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487996/2023-08-07"},"date":{"value":"2023-08-07"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000303","node_attrs":{"div":16,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G173397A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-"]}},"children":[{"name":"OR743499","node_attrs":{"div":16,"accession":"OR743499","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1030"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR743499/2023-10-XX"},"date":{"value":"2023-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OR743500","node_attrs":{"div":16,"accession":"OR743500","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1031"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR743500/2023-10-XX"},"date":{"value":"2023-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"OR487992","node_attrs":{"div":16,"accession":"OR487992","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0672/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487992/2023-08-02"},"date":{"value":"2023-08-02"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-179244T","-179245C","-179246G","-179247T","-179248T","-179249A","-179250T","-179251T","-179252G","-179253T","-179254T","-179255T","-179256G","-179257G","-179258T","-179259C","-179260T","-179261A","-179262T","-179263G"]}}}]}]}]},{"name":"NODE_0000304","node_attrs":{"div":14,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G13563A"],"OPG025":["P569S"]},"labels":{"aa":"OPG025: P569S"}},"children":[{"name":"OR381843","node_attrs":{"div":14,"accession":"OR381843","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0649/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381843/2023-07-10"},"date":{"value":"2023-07-10"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OR381837","node_attrs":{"div":16,"accession":"OR381837","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0640/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381837/2023-06-27"},"date":{"value":"2023-06-27"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C29342T","C148438T","G150556A"],"OPG046":["E130K"],"OPG174":["E320K"]},"labels":{"aa":"OPG046: E130K; OPG174: E320K"}}},{"name":"OR381835","node_attrs":{"div":14,"accession":"OR381835","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0638/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381835/2023-06-27"},"date":{"value":"2023-06-27"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OR381834","node_attrs":{"div":15,"accession":"OR381834","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0636/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381834/2023-06-29"},"date":{"value":"2023-06-29"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G55497A"]}}},{"name":"OR381833","node_attrs":{"div":15,"accession":"OR381833","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0634/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381833/2023-07-03"},"date":{"value":"2023-07-03"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C176877T","-179186T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-"],"OPG205":["H408Y"]},"labels":{"aa":"OPG205: H408Y"}}},{"name":"OR326994","node_attrs":{"div":14,"accession":"OR326994","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0630/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR326994/2023-06-22"},"date":{"value":"2023-06-22"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-608T","G610-","T611-","-179186T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-"]}}},{"name":"OR326993","node_attrs":{"div":14,"accession":"OR326993","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0629/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR326993/2023-06-20"},"date":{"value":"2023-06-20"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"]}}},{"name":"OR488000","node_attrs":{"div":17,"accession":"OR488000","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0682/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR488000/2023-08-07"},"date":{"value":"2023-08-07"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G49821A","G87187A","C190352T"],"OPG068":["E541K"],"OPG109":["S754L"]},"labels":{"aa":"OPG068: E541K; OPG109: S754L"}}},{"name":"OR487982","node_attrs":{"div":14,"accession":"OR487982","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0660/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487982/2023-07-26"},"date":{"value":"2023-07-26"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-607T"]}}},{"name":"OR487981","node_attrs":{"div":14,"accession":"OR487981","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0657/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487981/2023-07-21"},"date":{"value":"2023-07-21"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000305","node_attrs":{"div":15,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C117631T"],"OPG136":["D653N"]},"labels":{"aa":"OPG136: D653N"}},"children":[{"name":"OR381840","node_attrs":{"div":15,"accession":"OR381840","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0644/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381840/2023-07-07"},"date":{"value":"2023-07-07"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OR381839","node_attrs":{"div":15,"accession":"OR381839","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0643/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381839/2023-07-04"},"date":{"value":"2023-07-04"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000306","node_attrs":{"div":16,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C121394T","G162280A"],"OPG188":["E229K"]},"labels":{"aa":"OPG188: E229K"}},"children":[{"name":"OR743496","node_attrs":{"div":16,"accession":"OR743496","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1027"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR743496/2023-10-XX"},"date":{"value":"2023-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OR487994","node_attrs":{"div":16,"accession":"OR487994","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0674/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487994/2023-08-03"},"date":{"value":"2023-08-03"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OR487993","node_attrs":{"div":16,"accession":"OR487993","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0673/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487993/2023-08-03"},"date":{"value":"2023-08-03"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000307","node_attrs":{"div":15,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C37738T"],"OPG056":["E433K"]},"labels":{"aa":"OPG056: E433K"}},"children":[{"name":"OR487984","node_attrs":{"div":16,"accession":"OR487984","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0663/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487984/2023-07-28"},"date":{"value":"2023-07-28"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C15258T"],"OPG025":["D4N"]},"labels":{"aa":"OPG025: D4N"}}},{"name":"NODE_0000308","node_attrs":{"div":16,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G151847A"]}},"children":[{"name":"OR381844","node_attrs":{"div":18,"accession":"OR381844","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0650/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381844/2023-07-18"},"date":{"value":"2023-07-18"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-609T","G610-","T611-","G138584A","G151875A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-"],"OPG156":["R276W"],"OPG178":["D123N"]},"labels":{"aa":"OPG156: R276W; OPG178: D123N"}}},{"name":"OR381836","node_attrs":{"div":16,"accession":"OR381836","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0639/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381836/2023-06-27"},"date":{"value":"2023-06-27"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OR381838","node_attrs":{"div":17,"accession":"OR381838","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0641/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381838/2023-07-04"},"date":{"value":"2023-07-04"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-607T","-609T","G610-","T611-","C82619T"]}}},{"name":"OR326997","node_attrs":{"div":16,"accession":"OR326997","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0633/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR326997/2023-06-25"},"date":{"value":"2023-06-25"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-608T","G610-","T611-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-"]}}},{"name":"OR326995","node_attrs":{"div":17,"accession":"OR326995","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0631/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR326995/2023-06-22"},"date":{"value":"2023-06-22"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G695-","T696-","C34435T","A196625-","T196626-"],"OPG053":["A86T"]},"labels":{"aa":"OPG053: A86T"}}},{"name":"OR487997","node_attrs":{"div":16,"accession":"OR487997","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0679/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487997/2023-08-08"},"date":{"value":"2023-08-08"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OR487985","node_attrs":{"div":21,"accession":"OR487985","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0664/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487985/2023-08-01"},"date":{"value":"2023-08-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C62243T","A132145G","G150054A","C162248T","G164445A"],"OPG081":["V15I"],"OPG176":["M82I"],"OPG188":["S218F"]},"labels":{"aa":"OPG081: V15I; OPG176: M82I; OPG188: S218F"}}},{"name":"OR487988","node_attrs":{"div":16,"accession":"OR487988","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0667/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487988/2023-08-01"},"date":{"value":"2023-08-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["A784-","T785-","T196689-","C196690-"]}}},{"name":"OR487980","node_attrs":{"div":16,"accession":"OR487980","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0656/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487980/2023-07-21"},"date":{"value":"2023-07-21"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T606-","A196614-"]}}},{"name":"OR487979","node_attrs":{"div":18,"accession":"OR487979","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0655/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487979/2023-07-21"},"date":{"value":"2023-07-21"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T12827C","C15258T"],"OPG023":["N25S"],"OPG025":["D4N"]},"labels":{"aa":"OPG023: N25S; OPG025: D4N"}}},{"name":"NODE_0000309","node_attrs":{"div":19,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C56879T","C57492T","G121291A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","A196614-"],"OPG074":["E83K"],"OPG075":["E3K"]},"labels":{"aa":"OPG074: E83K; OPG075: E3K"}},"children":[{"name":"OR449307","node_attrs":{"div":21,"accession":"OR449307","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1021"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR449307/2023-08-XX"},"date":{"value":"2023-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C84191T","C115068T","A179169-","T179170-","A179171-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG133":["R210K"]},"labels":{"aa":"OPG133: R210K"}}},{"name":"OR487976","node_attrs":{"div":20,"accession":"OR487976","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0652/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487976/2023-07-19"},"date":{"value":"2023-07-19"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T606-","-179244T","-179245C","-179246G","-179247T","-179248T","-179249A","-179250T","-179251T","-179252G","-179253T","-179254T","-179255T","-179256G","C181495T"],"OPG210":["S47L"]},"labels":{"aa":"OPG210: S47L"}}},{"name":"OR487978","node_attrs":{"div":21,"accession":"OR487978","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0654/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487978/2023-07-21"},"date":{"value":"2023-07-21"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T606-","T12827C","T12833A"],"OPG023":["N25S"]},"labels":{"aa":"OPG023: N25S"}}},{"name":"NODE_0000310","node_attrs":{"div":20,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G172945A"]}},"children":[{"name":"OR743493","node_attrs":{"div":20,"accession":"OR743493","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1024"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR743493/2023-08-XX"},"date":{"value":"2023-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OR519723","node_attrs":{"div":20,"accession":"OR519723","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR519723/2023-08-XX"},"date":{"value":"2023-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-179244T","-179245C","-179246G","-179247T","-179248T","-179249A","-179250T","-179251T","-179252G","-179253T","-179254T","-179255T","-179256G"]}}}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}} diff --git a/data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/CHANGELOG.md b/data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/CHANGELOG.md deleted file mode 100644 index 04463a94..00000000 --- a/data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/CHANGELOG.md +++ /dev/null @@ -1,7 +0,0 @@ -## Unreleased - -Initial release for Nextclade v3! - -This dataset is converted from the corresponding older dataset for Nextclade v2. You can find old versions of datasets here: https://github.com/nextstrain/nextclade_data/tree/2023-08-17--15-51-24--UTC/data/datasets - -Read more about Nextclade datasets in the documentation: https://docs.nextstrain.org/projects/nextclade/en/stable/user/datasets.html diff --git a/data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/README.md b/data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/README.md deleted file mode 100644 index 21a4bfe3..00000000 --- a/data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/README.md +++ /dev/null @@ -1,14 +0,0 @@ -# Nextclade dataset for "Human Monkeypox Lineage B.1*" based on reference "MPXV_USA_2022_MA001 in NC_063383 coordinates" (hMPXV_B1/pseudo_ON563414) - - -## Dataset attributes - -| attribute | value | value friendly | -| -------------------- | -------------------- | ---------------------------------------- | -| name | hMPXV_B1 | Human Monkeypox Lineage B.1* | -| reference | pseudo_ON563414 | MPXV_USA_2022_MA001 in NC_063383 coordinates | - - -## What is Nextclade dataset - -Read more about Nextclade datasets in Nextclade documentation: https://docs.nextstrain.org/projects/nextclade/en/stable/user/datasets.html diff --git a/data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/genome_annotation.gff3 b/data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/genome_annotation.gff3 deleted file mode 100644 index 32348669..00000000 --- a/data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/genome_annotation.gff3 +++ /dev/null @@ -1,361 +0,0 @@ -##sequence-region NC_063383.1 1 197209 -##species https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10244 -##NC_063383.1 RefSeq region 1 197209 . + . ID=NC_063383.1:1..197209;Dbxref=taxon:10244;collection-date=2018-08;country=Nigeria: Rivers State;gbkey=Src;genome=genomic;genotype=West African clade;isolate=MPXV-M5312_HM12_Rivers;mol_type=genomic DNA;nat-host=Homo sapiens -## Required edit of above line for augur translate -NC_063383.1 RefSeq source 1 197209 . + . gene_name=nuc;ID=NC_063383.1:1..197209;Dbxref=taxon:10244;collection-date=2018-08;country=Nigeria: Rivers State;gbkey=Src;genome=genomic;genotype=West African clade;isolate=MPXV-M5312_HM12_Rivers;mol_type=genomic DNA;nat-host=Homo sapiens -NC_063383.1 RefSeq gene 835 1575 . - . ID=gene-NBT03_gp001;Dbxref=GeneID:72551607;Name=OPG001;gbkey=Gene;gene_name=OPG001;gene_biotype=protein_coding;locus_tag=NBT03_gp001;old_locus_tag=MPXV-M5312_HM12_Rivers-001 -NC_063383.1 RefSeq CDS 835 1575 . - 0 ID=cds-YP_010377002.1;Parent=gene-NBT03_gp001;Dbxref=Genbank:YP_010377002.1,GeneID:72551607;Name=YP_010377002.1;Note=J1L%3B similar to Vaccinia virus strain Copenhagen C23L%3B most abundant secreted protein%3B CC-chemokine binding;gbkey=CDS;gene_name=OPG001;locus_tag=NBT03_gp001;product=MPXVgp001;protein_id=YP_010377002.1 -NC_063383.1 RefSeq gene 1702 2751 . - . ID=gene-NBT03_gp002;Dbxref=GeneID:72551418;Name=OPG002;gbkey=Gene;gene_name=OPG002;gene_biotype=protein_coding;locus_tag=NBT03_gp002;old_locus_tag=MPXV-M5312_HM12_Rivers-002 -NC_063383.1 RefSeq CDS 1702 2751 . - 0 ID=cds-YP_010377003.1;Parent=gene-NBT03_gp002;Dbxref=Genbank:YP_010377003.1,GeneID:72551418;Name=YP_010377003.1;Note=J2L;gbkey=CDS;gene_name=OPG002;locus_tag=NBT03_gp002;product=MPXVgp002;protein_id=YP_010377003.1 -NC_063383.1 RefSeq gene 2841 4607 . - . ID=gene-NBT03_gp003;Dbxref=GeneID:72551419;Name=OPG003;gbkey=Gene;gene_name=OPG003;gene_biotype=protein_coding;locus_tag=NBT03_gp003;old_locus_tag=MPXV-M5312_HM12_Rivers-003 -NC_063383.1 RefSeq CDS 2841 4607 . - 0 ID=cds-YP_010377004.1;Parent=gene-NBT03_gp003;Dbxref=Genbank:YP_010377004.1,GeneID:72551419;Name=YP_010377004.1;Note=J3L;gbkey=CDS;gene_name=OPG003;locus_tag=NBT03_gp003;product=MPXVgp003;protein_id=YP_010377004.1 -NC_063383.1 RefSeq gene 4843 6156 . - . ID=gene-NBT03_gp004;Dbxref=GeneID:72551420;Name=OPG015;gbkey=Gene;gene_name=OPG015;gene_biotype=protein_coding;locus_tag=NBT03_gp004;old_locus_tag=MPXV-M5312_HM12_Rivers-004 -NC_063383.1 RefSeq CDS 4843 6156 . - 0 ID=cds-YP_010377005.1;Parent=gene-NBT03_gp004;Dbxref=Genbank:YP_010377005.1,GeneID:72551420;Name=YP_010377005.1;Note=D1L;gbkey=CDS;gene_name=OPG015;locus_tag=NBT03_gp004;product=MPXVgp004;protein_id=YP_010377005.1 -NC_063383.1 RefSeq gene 7580 8008 . + . ID=gene-NBT03_gp005;Dbxref=GeneID:72551421;Name=OPG019;gbkey=Gene;gene_name=OPG019;gene_biotype=protein_coding;locus_tag=NBT03_gp005;old_locus_tag=MPXV-M5312_HM12_Rivers-006 -NC_063383.1 RefSeq CDS 7580 8008 . + 0 ID=cds-YP_010377006.1;Parent=gene-NBT03_gp005;Dbxref=Genbank:YP_010377006.1,GeneID:72551421;Name=YP_010377006.1;Note=D3R%3B similar to Vaccinia virus strain Copenhagen C11R%3B secreted growth factor;gbkey=CDS;gene_name=OPG019;locus_tag=NBT03_gp005;product=MPXVgp006;protein_id=YP_010377006.1 -NC_063383.1 RefSeq gene 9587 10315 . + . ID=gene-NBT03_gp006;Dbxref=GeneID:72551422;Name=OPG021;gbkey=Gene;gene_name=OPG021;gene_biotype=protein_coding;locus_tag=NBT03_gp006;old_locus_tag=MPXV-M5312_HM12_Rivers-008 -NC_063383.1 RefSeq CDS 9587 10315 . + 0 ID=cds-YP_010377007.1;Parent=gene-NBT03_gp006;Dbxref=Genbank:YP_010377007.1,GeneID:72551422;Name=YP_010377007.1;Note=D5R%3B zinc binding%3B virosome localization%3B virulence factor%3B inhibition of apoptosis induced by UV irradiation;gbkey=CDS;gene_name=OPG021;locus_tag=NBT03_gp006;product=MPXVgp008;protein_id=YP_010377007.1 -NC_063383.1 RefSeq gene 10478 10858 . - . ID=gene-NBT03_gp007;Dbxref=GeneID:72551423;Name=OPG022;gbkey=Gene;gene_name=OPG022;gene_biotype=protein_coding;locus_tag=NBT03_gp007;old_locus_tag=MPXV-M5312_HM12_Rivers-009 -NC_063383.1 RefSeq CDS 10478 10858 . - 0 ID=cds-YP_010377008.1;Parent=gene-NBT03_gp007;Dbxref=Genbank:YP_010377008.1,GeneID:72551423;Name=YP_010377008.1;Note=D6L%3B secreted IL-18 binding protein;gbkey=CDS;gene_name=OPG022;locus_tag=NBT03_gp007;product=MPXVgp009;protein_id=YP_010377008.1 -NC_063383.1 RefSeq gene 10918 12900 . - . ID=gene-NBT03_gp008;Dbxref=GeneID:72551424;Name=OPG023;gbkey=Gene;gene_name=OPG023;gene_biotype=protein_coding;locus_tag=NBT03_gp008;old_locus_tag=MPXV-M5312_HM12_Rivers-010 -NC_063383.1 RefSeq CDS 10918 12900 . - 0 ID=cds-YP_010377009.1;Parent=gene-NBT03_gp008;Dbxref=Genbank:YP_010377009.1,GeneID:72551424;Name=YP_010377009.1;Note=D7L%3B host range%3B ankyrin-like;gbkey=CDS;gene_name=OPG023;locus_tag=NBT03_gp008;product=MPXVgp010;protein_id=YP_010377009.1 -NC_063383.1 RefSeq gene 13034 13228 . - . ID=gene-NBT03_gp009;Dbxref=GeneID:72551425;Name=OPG024;gbkey=Gene;gene_name=OPG024;gene_biotype=protein_coding;locus_tag=NBT03_gp009;old_locus_tag=MPXV-M5312_HM12_Rivers-011 -NC_063383.1 RefSeq CDS 13034 13228 . - 0 ID=cds-YP_010377010.1;Parent=gene-NBT03_gp009;Dbxref=Genbank:YP_010377010.1,GeneID:72551425;Name=YP_010377010.1;Note=D8L;gbkey=CDS;gene_name=OPG024;locus_tag=NBT03_gp009;product=MPXVgp011;protein_id=YP_010377010.1 -NC_063383.1 RefSeq gene 13375 15267 . - . ID=gene-NBT03_gp010;Dbxref=GeneID:72551426;Name=OPG025;gbkey=Gene;gene_name=OPG025;gene_biotype=protein_coding;locus_tag=NBT03_gp010;old_locus_tag=MPXV-M5312_HM12_Rivers-012 -NC_063383.1 RefSeq CDS 13375 15267 . - 0 ID=cds-YP_010377011.1;Parent=gene-NBT03_gp010;Dbxref=Genbank:YP_010377011.1,GeneID:72551426;Name=YP_010377011.1;Note=D9L%3B similar to Vaccinia virus strain Copenhagen C9L%3B ankyrin-like;gbkey=CDS;gene_name=OPG025;locus_tag=NBT03_gp010;product=MPXVgp012;protein_id=YP_010377011.1 -NC_063383.1 RefSeq gene 15925 16377 . - . ID=gene-NBT03_gp011;Dbxref=GeneID:72551427;Name=OPG027;gbkey=Gene;gene_name=OPG027;gene_biotype=protein_coding;locus_tag=NBT03_gp011;old_locus_tag=MPXV-M5312_HM12_Rivers-013 -NC_063383.1 RefSeq CDS 15925 16377 . - 0 ID=cds-YP_010377012.1;Parent=gene-NBT03_gp011;Dbxref=Genbank:YP_010377012.1,GeneID:72551427;Name=YP_010377012.1;Note=D10L%3B similar to Vaccinia virus strain Copenhagen C7L%3B host range;gbkey=CDS;gene_name=OPG027;locus_tag=NBT03_gp011;product=MPXVgp013;protein_id=YP_010377012.1 -NC_063383.1 RefSeq gene 16602 17069 . - . ID=gene-NBT03_gp012;Dbxref=GeneID:72551428;Name=OPG029;gbkey=Gene;gene_name=OPG029;gene_biotype=protein_coding;locus_tag=NBT03_gp012;old_locus_tag=MPXV-M5312_HM12_Rivers-014 -NC_063383.1 RefSeq CDS 16602 17069 . - 0 ID=cds-YP_010377013.1;Parent=gene-NBT03_gp012;Dbxref=Genbank:YP_010377013.1,GeneID:72551428;Name=YP_010377013.1;Note=D11L%3B similar to Vaccinia virus strain Copenhagen C6L;gbkey=CDS;gene_name=OPG029;locus_tag=NBT03_gp012;product=MPXVgp014;protein_id=YP_010377013.1 -NC_063383.1 RefSeq gene 17213 17833 . - . ID=gene-NBT03_gp013;Dbxref=GeneID:72551429;Name=OPG030;gbkey=Gene;gene_name=OPG030;gene_biotype=protein_coding;locus_tag=NBT03_gp013;old_locus_tag=MPXV-M5312_HM12_Rivers-015 -NC_063383.1 RefSeq CDS 17213 17833 . - 0 ID=cds-YP_010377014.1;Parent=gene-NBT03_gp013;Dbxref=Genbank:YP_010377014.1,GeneID:72551429;Name=YP_010377014.1;Note=D12L%3B similar to Vaccinia virus strain Copenhagen C5L%3B BTB domain of kelch-like protein;gbkey=CDS;gene_name=OPG030;locus_tag=NBT03_gp013;product=MPXVgp015;protein_id=YP_010377014.1 -NC_063383.1 RefSeq gene 17878 18828 . - . ID=gene-NBT03_gp014;Dbxref=GeneID:72551430;Name=OPG031;gbkey=Gene;gene_name=OPG031;gene_biotype=protein_coding;locus_tag=NBT03_gp014;old_locus_tag=MPXV-M5312_HM12_Rivers-016 -NC_063383.1 RefSeq CDS 17878 18828 . - 0 ID=cds-YP_010377015.1;Parent=gene-NBT03_gp014;Dbxref=Genbank:YP_010377015.1,GeneID:72551430;Name=YP_010377015.1;Note=D13L%3B similar to Vaccinia virus strain Copenhagen C4L;gbkey=CDS;gene_name=OPG031;locus_tag=NBT03_gp014;product=MPXVgp016;protein_id=YP_010377015.1 -NC_063383.1 RefSeq gene 19361 20005 . - . ID=gene-NBT03_gp015;Dbxref=GeneID:72551431;Name=OPG034;gbkey=Gene;gene_name=OPG034;gene_biotype=protein_coding;locus_tag=NBT03_gp015;old_locus_tag=MPXV-M5312_HM12_Rivers-018 -NC_063383.1 RefSeq CDS 19361 20005 . - 0 ID=cds-YP_010377017.1;Parent=gene-NBT03_gp015;Dbxref=Genbank:YP_010377017.1,GeneID:72551431;Name=YP_010377017.1;Note=D19L%3B similar to Vaccinia virus strain Copenhagen C1L;gbkey=CDS;gene_name=OPG034;locus_tag=NBT03_gp015;product=MPXVgp022;protein_id=YP_010377017.1 -NC_063383.1 RefSeq gene 20051 20404 . - . ID=gene-NBT03_gp016;Dbxref=GeneID:72551432;Name=OPG035;gbkey=Gene;gene_name=OPG035;gene_biotype=protein_coding;locus_tag=NBT03_gp016;old_locus_tag=MPXV-M5312_HM12_Rivers-019 -NC_063383.1 RefSeq CDS 20051 20404 . - 0 ID=cds-YP_010377018.1;Parent=gene-NBT03_gp016;Dbxref=Genbank:YP_010377018.1,GeneID:72551432;Name=YP_010377018.1;Note=P1L%3B similar to Vaccinia virus strain Copenhagen N1L%3B secreted virulence factor;gbkey=CDS;gene_name=OPG035;locus_tag=NBT03_gp016;product=MPXVgp023;protein_id=YP_010377018.1 -NC_063383.1 RefSeq gene 20531 21064 . - . ID=gene-NBT03_gp017;Dbxref=GeneID:72551433;Name=OPG036;gbkey=Gene;gene_name=OPG036;gene_biotype=protein_coding;locus_tag=NBT03_gp017;old_locus_tag=MPXV-M5312_HM12_Rivers-020 -NC_063383.1 RefSeq CDS 20531 21064 . - 0 ID=cds-YP_010377019.1;Parent=gene-NBT03_gp017;Dbxref=Genbank:YP_010377019.1,GeneID:72551433;Name=YP_010377019.1;Note=P2L%3B similar to Vaccinia virus strain Copenhagen N2L;gbkey=CDS;gene_name=OPG036;locus_tag=NBT03_gp017;product=MPXVgp024;protein_id=YP_010377019.1 -NC_063383.1 RefSeq gene 21105 22433 . - . ID=gene-NBT03_gp018;Dbxref=GeneID:72551434;Name=OPG037;gbkey=Gene;gene_name=OPG037;gene_biotype=protein_coding;locus_tag=NBT03_gp018;old_locus_tag=MPXV-M5312_HM12_Rivers-021 -NC_063383.1 RefSeq CDS 21105 22433 . - 0 ID=cds-YP_010377020.1;Parent=gene-NBT03_gp018;Dbxref=Genbank:YP_010377020.1,GeneID:72551434;Name=YP_010377020.1;Note=O1L%3B similar to Vaccinia virus strain Copenhagen M1L%3B ankyrin-like;gbkey=CDS;gene_name=OPG037;locus_tag=NBT03_gp018;product=MPXVgp025;protein_id=YP_010377020.1 -NC_063383.1 RefSeq gene 22497 23159 . - . ID=gene-NBT03_gp019;Dbxref=GeneID:72551435;Name=OPG038;gbkey=Gene;gene_name=OPG038;gene_biotype=protein_coding;locus_tag=NBT03_gp019;old_locus_tag=MPXV-M5312_HM12_Rivers-022 -NC_063383.1 RefSeq CDS 22497 23159 . - 0 ID=cds-YP_010377021.1;Parent=gene-NBT03_gp019;Dbxref=Genbank:YP_010377021.1,GeneID:72551435;Name=YP_010377021.1;Note=O2L%3B similar to Vaccinia virus strain Copenhagen M2L;gbkey=CDS;gene_name=OPG038;locus_tag=NBT03_gp019;product=MPXVgp026;protein_id=YP_010377021.1 -NC_063383.1 RefSeq gene 23264 24118 . - . ID=gene-NBT03_gp020;Dbxref=GeneID:72551436;Name=OPG039;gbkey=Gene;gene_name=OPG039;gene_biotype=protein_coding;locus_tag=NBT03_gp020;old_locus_tag=MPXV-M5312_HM12_Rivers-023 -NC_063383.1 RefSeq CDS 23264 24118 . - 0 ID=cds-YP_010377022.1;Parent=gene-NBT03_gp020;Dbxref=Genbank:YP_010377022.1,GeneID:72551436;Name=YP_010377022.1;Note=C1L%3B similar to Vaccinia virus strain Copenhagen K1L%3B host range%3B ankyrin-like;gbkey=CDS;gene_name=OPG039;locus_tag=NBT03_gp020;product=MPXVgp027;protein_id=YP_010377022.1 -NC_063383.1 RefSeq gene 24351 25478 . - . ID=gene-NBT03_gp021;Dbxref=GeneID:72551437;Name=OPG040;gbkey=Gene;gene_name=OPG040;gene_biotype=protein_coding;locus_tag=NBT03_gp021;old_locus_tag=MPXV-M5312_HM12_Rivers-024 -NC_063383.1 RefSeq CDS 24351 25478 . - 0 ID=cds-YP_010377023.1;Parent=gene-NBT03_gp021;Dbxref=Genbank:YP_010377023.1,GeneID:72551437;Name=YP_010377023.1;Note=SPI-3%3B C2L%3B similar to Vaccinia virus strain Copenhagen K2L%3B serine protease inhibitor-like%2C SPI-3%3B inhibition of the ability of infected cells to fuse;gbkey=CDS;gene_name=OPG040;locus_tag=NBT03_gp021;product=MPXVgp028;protein_id=YP_010377023.1 -NC_063383.1 RefSeq gene 25823 27097 . - . ID=gene-NBT03_gp022;Dbxref=GeneID:72551438;Name=OPG042;gbkey=Gene;gene_name=OPG042;gene_biotype=protein_coding;locus_tag=NBT03_gp022;old_locus_tag=MPXV-M5312_HM12_Rivers-026 -NC_063383.1 RefSeq CDS 25823 27097 . - 0 ID=cds-YP_010377025.1;Parent=gene-NBT03_gp022;Dbxref=Genbank:YP_010377025.1,GeneID:72551438;Name=YP_010377025.1;Note=C4L%3B similar to Vaccinia virus strain Copenhagen K4L%3B phospholipase D-like;gbkey=CDS;gene_name=OPG042;locus_tag=NBT03_gp022;product=MPXVgp030;protein_id=YP_010377025.1 -NC_063383.1 RefSeq gene 27125 27955 . - . ID=gene-NBT03_gp023;Dbxref=GeneID:72551439;Name=OPG043;gbkey=Gene;gene_name=OPG043;gene_biotype=protein_coding;locus_tag=NBT03_gp023;old_locus_tag=MPXV-M5312_HM12_Rivers-027 -NC_063383.1 RefSeq CDS 27125 27955 . - 0 ID=cds-YP_010377026.1;Parent=gene-NBT03_gp023;Dbxref=Genbank:YP_010377026.1,GeneID:72551439;Name=YP_010377026.1;Note=C5L%3B lysophospholipase-like;gbkey=CDS;gene_name=OPG043;locus_tag=NBT03_gp023;product=MPXVgp031;protein_id=YP_010377026.1 -NC_063383.1 RefSeq gene 28091 28540 . + . ID=gene-NBT03_gp024;Dbxref=GeneID:72551440;Name=OPG044;gbkey=Gene;gene_name=OPG044;gene_biotype=protein_coding;locus_tag=NBT03_gp024;old_locus_tag=MPXV-M5312_HM12_Rivers-028 -NC_063383.1 RefSeq CDS 28091 28540 . + 0 ID=cds-YP_010377027.1;Parent=gene-NBT03_gp024;Dbxref=Genbank:YP_010377027.1,GeneID:72551440;Name=YP_010377027.1;Note=C6R%3B similar to Vaccinia virus strain Copenhagen K7R%3B VAC B15R-like;gbkey=CDS;gene_name=OPG044;locus_tag=NBT03_gp024;product=MPXVgp032;protein_id=YP_010377027.1 -NC_063383.1 RefSeq gene 28603 29262 . - . ID=gene-NBT03_gp025;Dbxref=GeneID:72551441;Name=OPG045;gbkey=Gene;gene_name=OPG045;gene_biotype=protein_coding;locus_tag=NBT03_gp025;old_locus_tag=MPXV-M5312_HM12_Rivers-029 -NC_063383.1 RefSeq CDS 28603 29262 . - 0 ID=cds-YP_010377028.1;Parent=gene-NBT03_gp025;Dbxref=Genbank:YP_010377028.1,GeneID:72551441;Name=YP_010377028.1;Note=C7L%3B similar to Vaccinia virus strain Copenhagen F1L;gbkey=CDS;gene_name=OPG045;locus_tag=NBT03_gp025;product=MPXVgp033;protein_id=YP_010377028.1 -NC_063383.1 RefSeq gene 29274 29729 . - . ID=gene-NBT03_gp026;Dbxref=GeneID:72551442;Name=OPG046;gbkey=Gene;gene_name=OPG046;gene_biotype=protein_coding;locus_tag=NBT03_gp026;old_locus_tag=MPXV-M5312_HM12_Rivers-030 -NC_063383.1 RefSeq CDS 29274 29729 . - 0 ID=cds-YP_010377029.1;Parent=gene-NBT03_gp026;Dbxref=Genbank:YP_010377029.1,GeneID:72551442;Name=YP_010377029.1;Note=C8L%3B similar to Vaccinia virus strain Copenhagen F2L%3B deoxyuridine triphosphatase;gbkey=CDS;gene_name=OPG046;locus_tag=NBT03_gp026;product=MPXVgp034;protein_id=YP_010377029.1 -NC_063383.1 RefSeq gene 29746 31194 . - . ID=gene-NBT03_gp027;Dbxref=GeneID:72551443;Name=OPG047;gbkey=Gene;gene_name=OPG047;gene_biotype=protein_coding;locus_tag=NBT03_gp027;old_locus_tag=MPXV-M5312_HM12_Rivers-031 -NC_063383.1 RefSeq CDS 29746 31194 . - 0 ID=cds-YP_010377030.1;Parent=gene-NBT03_gp027;Dbxref=Genbank:YP_010377030.1,GeneID:72551443;Name=YP_010377030.1;Note=C9L%3B similar to Vaccinia virus strain Copenhagen F3L%3B kelch-like;gbkey=CDS;gene_name=OPG047;locus_tag=NBT03_gp027;product=MPXVgp035;protein_id=YP_010377030.1 -NC_063383.1 RefSeq gene 31205 32164 . - . ID=gene-NBT03_gp028;Dbxref=GeneID:72551444;Name=OPG048;gbkey=Gene;gene_name=OPG048;gene_biotype=protein_coding;locus_tag=NBT03_gp028;old_locus_tag=MPXV-M5312_HM12_Rivers-032 -NC_063383.1 RefSeq CDS 31205 32164 . - 0 ID=cds-YP_010377031.1;Parent=gene-NBT03_gp028;Dbxref=Genbank:YP_010377031.1,GeneID:72551444;Name=YP_010377031.1;Note=C10L%3B similar to Vaccinia virus strain Copenhagen F4L%3B ribonucleotide reductase%2C small subunit%2C R2;gbkey=CDS;gene_name=OPG048;locus_tag=NBT03_gp028;product=MPXVgp036;protein_id=YP_010377031.1 -NC_063383.1 RefSeq gene 32195 33151 . - . ID=gene-NBT03_gp029;Dbxref=GeneID:72551445;Name=OPG049;gbkey=Gene;gene_name=OPG049;gene_biotype=protein_coding;locus_tag=NBT03_gp029;old_locus_tag=MPXV-M5312_HM12_Rivers-033 -NC_063383.1 RefSeq CDS 32195 33151 . - 0 ID=cds-YP_010377032.1;Parent=gene-NBT03_gp029;Dbxref=Genbank:YP_010377032.1,GeneID:72551445;Name=YP_010377032.1;Note=C11L%3B similar to Vaccinia virus strain Copenhagen F5L;gbkey=CDS;gene_name=OPG049;locus_tag=NBT03_gp029;product=MPXVgp037;protein_id=YP_010377032.1 -NC_063383.1 RefSeq gene 33181 33408 . - . ID=gene-NBT03_gp030;Dbxref=GeneID:72551446;Name=OPG050;gbkey=Gene;gene_name=OPG050;gene_biotype=protein_coding;locus_tag=NBT03_gp030;old_locus_tag=MPXV-M5312_HM12_Rivers-034 -NC_063383.1 RefSeq CDS 33181 33408 . - 0 ID=cds-YP_010377033.1;Parent=gene-NBT03_gp030;Dbxref=Genbank:YP_010377033.1,GeneID:72551446;Name=YP_010377033.1;Note=C12L%3B similar to Vaccinia virus strain Copenhagen F6L;gbkey=CDS;gene_name=OPG050;locus_tag=NBT03_gp030;product=MPXVgp038;protein_id=YP_010377033.1 -NC_063383.1 RefSeq gene 33425 33649 . - . ID=gene-NBT03_gp031;Dbxref=GeneID:72551447;Name=OPG051;gbkey=Gene;gene_name=OPG051;gene_biotype=protein_coding;locus_tag=NBT03_gp031;old_locus_tag=MPXV-M5312_HM12_Rivers-035 -NC_063383.1 RefSeq CDS 33425 33649 . - 0 ID=cds-YP_010377034.1;Parent=gene-NBT03_gp031;Dbxref=Genbank:YP_010377034.1,GeneID:72551447;Name=YP_010377034.1;Note=C13L%3B similar to Vaccinia virus strain Copenhagen F7L;gbkey=CDS;gene_name=OPG051;locus_tag=NBT03_gp031;product=MPXVgp039;protein_id=YP_010377034.1 -NC_063383.1 RefSeq gene 33801 33995 . - . ID=gene-NBT03_gp032;Dbxref=GeneID:72551448;Name=OPG052;gbkey=Gene;gene_name=OPG052;gene_biotype=protein_coding;locus_tag=NBT03_gp032;old_locus_tag=MPXV-M5312_HM12_Rivers-036 -NC_063383.1 RefSeq CDS 33801 33995 . - 0 ID=cds-YP_010377035.1;Parent=gene-NBT03_gp032;Dbxref=Genbank:YP_010377035.1,GeneID:72551448;Name=YP_010377035.1;Note=C14L%3B similar to Vaccinia virus strain Copenhagen F8L;gbkey=CDS;gene_name=OPG052;locus_tag=NBT03_gp032;product=MPXVgp040;protein_id=YP_010377035.1 -NC_063383.1 RefSeq gene 34052 34690 . - . ID=gene-NBT03_gp033;Dbxref=GeneID:72551449;Name=OPG053;gbkey=Gene;gene_name=OPG053;gene_biotype=protein_coding;locus_tag=NBT03_gp033;old_locus_tag=MPXV-M5312_HM12_Rivers-037 -NC_063383.1 RefSeq CDS 34052 34690 . - 0 ID=cds-YP_010377036.1;Parent=gene-NBT03_gp033;Dbxref=Genbank:YP_010377036.1,GeneID:72551449;Name=YP_010377036.1;Note=C15L%3B similar to Vaccinia virus strain Copenhagen F9L;gbkey=CDS;gene_name=OPG053;locus_tag=NBT03_gp033;product=MPXVgp041;protein_id=YP_010377036.1 -NC_063383.1 RefSeq gene 34677 35996 . - . ID=gene-NBT03_gp034;Dbxref=GeneID:72551450;Name=OPG054;gbkey=Gene;gene_name=OPG054;gene_biotype=protein_coding;locus_tag=NBT03_gp034;old_locus_tag=MPXV-M5312_HM12_Rivers-038 -NC_063383.1 RefSeq CDS 34677 35996 . - 0 ID=cds-YP_010377037.1;Parent=gene-NBT03_gp034;Dbxref=Genbank:YP_010377037.1,GeneID:72551450;Name=YP_010377037.1;Note=C16L%3B similar to Vaccinia virus strain Copenhagen F10L%3B serine;gbkey=CDS;gene_name=OPG054;locus_tag=NBT03_gp034;product=MPXVgp042;protein_id=YP_010377037.1 -NC_063383.1 RefSeq gene 36019 37083 . - . ID=gene-NBT03_gp035;Dbxref=GeneID:72551451;Name=OPG055;gbkey=Gene;gene_name=OPG055;gene_biotype=protein_coding;locus_tag=NBT03_gp035;old_locus_tag=MPXV-M5312_HM12_Rivers-039 -NC_063383.1 RefSeq CDS 36019 37083 . - 0 ID=cds-YP_010377038.1;Parent=gene-NBT03_gp035;Dbxref=Genbank:YP_010377038.1,GeneID:72551451;Name=YP_010377038.1;Note=C17L%3B similar to Vaccinia virus strain Copenhagen F11L;gbkey=CDS;gene_name=OPG055;locus_tag=NBT03_gp035;product=MPXVgp043;protein_id=YP_010377038.1 -NC_063383.1 RefSeq gene 37127 39034 . - . ID=gene-NBT03_gp036;Dbxref=GeneID:72551452;Name=OPG056;gbkey=Gene;gene_name=OPG056;gene_biotype=protein_coding;locus_tag=NBT03_gp036;old_locus_tag=MPXV-M5312_HM12_Rivers-040 -NC_063383.1 RefSeq CDS 37127 39034 . - 0 ID=cds-YP_010377039.1;Parent=gene-NBT03_gp036;Dbxref=Genbank:YP_010377039.1,GeneID:72551452;Name=YP_010377039.1;Note=C18L%3B similar to Vaccinia virus strain Copenhagen F12L%3B actin tail formation;gbkey=CDS;gene_name=OPG056;locus_tag=NBT03_gp036;product=MPXVgp044;protein_id=YP_010377039.1 -NC_063383.1 RefSeq gene 39077 40195 . - . ID=gene-NBT03_gp037;Dbxref=GeneID:72551453;Name=OPG057;gbkey=Gene;gene_name=OPG057;gene_biotype=protein_coding;locus_tag=NBT03_gp037;old_locus_tag=MPXV-M5312_HM12_Rivers-041 -NC_063383.1 RefSeq CDS 39077 40195 . - 0 ID=cds-YP_010377040.1;Parent=gene-NBT03_gp037;Dbxref=Genbank:YP_010377040.1,GeneID:72551453;Name=YP_010377040.1;Note=C19L%3B similar to Vaccinia virus strain Copenhagen F13L%3B major envelope antigen of EEV%3B wrapping of IMV to form IEV%3B phospholipase D-like;gbkey=CDS;gene_name=OPG057;locus_tag=NBT03_gp037;product=MPXVgp045;protein_id=YP_010377040.1 -NC_063383.1 RefSeq gene 40213 40434 . - . ID=gene-NBT03_gp038;Dbxref=GeneID:72551454;Name=OPG058;gbkey=Gene;gene_name=OPG058;gene_biotype=protein_coding;locus_tag=NBT03_gp038;old_locus_tag=MPXV-M5312_HM12_Rivers-042 -NC_063383.1 RefSeq CDS 40213 40434 . - 0 ID=cds-YP_010377041.1;Parent=gene-NBT03_gp038;Dbxref=Genbank:YP_010377041.1,GeneID:72551454;Name=YP_010377041.1;Note=C20L%3B similar to Vaccinia virus strain Copenhagen F14L;gbkey=CDS;gene_name=OPG058;locus_tag=NBT03_gp038;product=MPXVgp046;protein_id=YP_010377041.1 -NC_063383.1 RefSeq gene 40484 40633 . - . ID=gene-NBT03_gp039;Dbxref=GeneID:72551455;Name=OPG059;gbkey=Gene;gene_name=OPG059;gene_biotype=protein_coding;locus_tag=NBT03_gp039;old_locus_tag=MPXV-M5312_HM12_Rivers-043 -NC_063383.1 RefSeq CDS 40484 40633 . - 0 ID=cds-YP_010377042.1;Parent=gene-NBT03_gp039;Dbxref=Genbank:YP_010377042.1,GeneID:72551455;Name=YP_010377042.1;gbkey=CDS;gene_name=OPG059;locus_tag=NBT03_gp039;product=C20.5L;protein_id=YP_010377042.1 -NC_063383.1 RefSeq gene 40706 41182 . - . ID=gene-NBT03_gp040;Dbxref=GeneID:72551456;Name=OPG060;gbkey=Gene;gene_name=OPG060;gene_biotype=protein_coding;locus_tag=NBT03_gp040;old_locus_tag=MPXV-M5312_HM12_Rivers-044 -NC_063383.1 RefSeq CDS 40706 41182 . - 0 ID=cds-YP_010377043.1;Parent=gene-NBT03_gp040;Dbxref=Genbank:YP_010377043.1,GeneID:72551456;Name=YP_010377043.1;Note=C21L%3B similar to Vaccinia virus strain Copenhagen F15L;gbkey=CDS;gene_name=OPG060;locus_tag=NBT03_gp040;product=MPXVgp047;protein_id=YP_010377043.1 -NC_063383.1 RefSeq gene 41189 41884 . - . ID=gene-NBT03_gp041;Dbxref=GeneID:72551457;Name=OPG061;gbkey=Gene;gene_name=OPG061;gene_biotype=protein_coding;locus_tag=NBT03_gp041;old_locus_tag=MPXV-M5312_HM12_Rivers-045 -NC_063383.1 RefSeq CDS 41189 41884 . - 0 ID=cds-YP_010377044.1;Parent=gene-NBT03_gp041;Dbxref=Genbank:YP_010377044.1,GeneID:72551457;Name=YP_010377044.1;Note=C22L%3B similar to Vaccinia virus strain Copenhagen F16L;gbkey=CDS;gene_name=OPG061;locus_tag=NBT03_gp041;product=MPXVgp048;protein_id=YP_010377044.1 -NC_063383.1 RefSeq gene 41947 42252 . + . ID=gene-NBT03_gp042;Dbxref=GeneID:72551458;Name=OPG062;gbkey=Gene;gene_name=OPG062;gene_biotype=protein_coding;locus_tag=NBT03_gp042;old_locus_tag=MPXV-M5312_HM12_Rivers-046 -NC_063383.1 RefSeq CDS 41947 42252 . + 0 ID=cds-YP_010377045.1;Parent=gene-NBT03_gp042;Dbxref=Genbank:YP_010377045.1,GeneID:72551458;Name=YP_010377045.1;Note=C23R%3B similar to Vaccinia virus strain Copenhagen F17R%3B virion core DNA-binding phosphoprotein;gbkey=CDS;gene_name=OPG062;locus_tag=NBT03_gp042;product=MPXVgp049;protein_id=YP_010377045.1 -NC_063383.1 RefSeq gene 42249 43688 . - . ID=gene-NBT03_gp043;Dbxref=GeneID:72551459;Name=OPG063;gbkey=Gene;gene_name=OPG063;gene_biotype=protein_coding;locus_tag=NBT03_gp043;old_locus_tag=MPXV-M5312_HM12_Rivers-047 -NC_063383.1 RefSeq CDS 42249 43688 . - 0 ID=cds-YP_010377046.1;Parent=gene-NBT03_gp043;Dbxref=Genbank:YP_010377046.1,GeneID:72551459;Name=YP_010377046.1;Note=F1L%3B similar to Vaccinia virus strain Copenhagen E1L%3B poly-A polymerase%2C catalytic subunit;gbkey=CDS;gene_name=OPG063;locus_tag=NBT03_gp043;product=MPXVgp050;protein_id=YP_010377046.1 -NC_063383.1 RefSeq gene 43685 45898 . - . ID=gene-NBT03_gp044;Dbxref=GeneID:72551460;Name=OPG064;gbkey=Gene;gene_name=OPG064;gene_biotype=protein_coding;locus_tag=NBT03_gp044;old_locus_tag=MPXV-M5312_HM12_Rivers-048 -NC_063383.1 RefSeq CDS 43685 45898 . - 0 ID=cds-YP_010377047.1;Parent=gene-NBT03_gp044;Dbxref=Genbank:YP_010377047.1,GeneID:72551460;Name=YP_010377047.1;Note=F2L%3B similar to Vaccinia virus strain Copenhagen E2L;gbkey=CDS;gene_name=OPG064;locus_tag=NBT03_gp044;product=MPXVgp051;protein_id=YP_010377047.1 -NC_063383.1 RefSeq gene 46022 46483 . - . ID=gene-NBT03_gp045;Dbxref=GeneID:72551461;Name=OPG065;gbkey=Gene;gene_name=OPG065;gene_biotype=protein_coding;locus_tag=NBT03_gp045;old_locus_tag=MPXV-M5312_HM12_Rivers-049 -NC_063383.1 RefSeq CDS 46022 46483 . - 0 ID=cds-YP_010377048.1;Parent=gene-NBT03_gp045;Dbxref=Genbank:YP_010377048.1,GeneID:72551461;Name=YP_010377048.1;Note=F3L%3B similar to Vaccinia virus strain Copenhagen E3L%3B interferon resistance factor%3B two forms (25 kDa and 19 kDa) of the dsRNA-binding protein%3B inhibition of dsRNA-dependent protein kinase and 2-5A-synthet;gbkey=CDS;gene_name=OPG065;locus_tag=NBT03_gp045;product=MPXVgp052;protein_id=YP_010377048.1 -NC_063383.1 RefSeq gene 46649 47428 . - . ID=gene-NBT03_gp046;Dbxref=GeneID:72551462;Name=OPG066;gbkey=Gene;gene_name=OPG066;gene_biotype=protein_coding;locus_tag=NBT03_gp046;old_locus_tag=MPXV-M5312_HM12_Rivers-050 -NC_063383.1 RefSeq CDS 46649 47428 . - 0 ID=cds-YP_010377049.1;Parent=gene-NBT03_gp046;Dbxref=Genbank:YP_010377049.1,GeneID:72551462;Name=YP_010377049.1;Note=F4L%3B similar to Vaccinia virus strain Copenhagen E4L%3B RNA polymerase 30 kDa subunit%3B simultaneously intermediate stage promoter-specific transcription factor%2C VITF-1;gbkey=CDS;gene_name=OPG066;locus_tag=NBT03_gp046;product=MPXVgp053;protein_id=YP_010377049.1 -NC_063383.1 RefSeq gene 48201 49904 . + . ID=gene-NBT03_gp047;Dbxref=GeneID:72551463;Name=OPG068;gbkey=Gene;gene_name=OPG068;gene_biotype=protein_coding;locus_tag=NBT03_gp047;old_locus_tag=MPXV-M5312_HM12_Rivers-052 -NC_063383.1 RefSeq CDS 48201 49904 . + 0 ID=cds-YP_010377051.1;Parent=gene-NBT03_gp047;Dbxref=Genbank:YP_010377051.1,GeneID:72551463;Name=YP_010377051.1;Note=F5R%3B similar to Vaccinia virus strain Copenhagen E6R;gbkey=CDS;gene_name=OPG068;locus_tag=NBT03_gp047;product=MPXVgp054;protein_id=YP_010377051.1 -NC_063383.1 RefSeq gene 49986 50486 . + . ID=gene-NBT03_gp048;Dbxref=GeneID:72551464;Name=OPG069;gbkey=Gene;gene_name=OPG069;gene_biotype=protein_coding;locus_tag=NBT03_gp048;old_locus_tag=MPXV-M5312_HM12_Rivers-053 -NC_063383.1 RefSeq CDS 49986 50486 . + 0 ID=cds-YP_010377052.1;Parent=gene-NBT03_gp048;Dbxref=Genbank:YP_010377052.1,GeneID:72551464;Name=YP_010377052.1;Note=F6R%3B similar to Vaccinia virus strain Copenhagen E7R%3B soluble myristylated protein;gbkey=CDS;gene_name=OPG069;locus_tag=NBT03_gp048;product=MPXVgp055;protein_id=YP_010377052.1 -NC_063383.1 RefSeq gene 50590 51411 . + . ID=gene-NBT03_gp049;Dbxref=GeneID:72551465;Name=OPG070;gbkey=Gene;gene_name=OPG070;gene_biotype=protein_coding;locus_tag=NBT03_gp049;old_locus_tag=MPXV-M5312_HM12_Rivers-054 -NC_063383.1 RefSeq CDS 50590 51411 . + 0 ID=cds-YP_010377053.1;Parent=gene-NBT03_gp049;Dbxref=Genbank:YP_010377053.1,GeneID:72551465;Name=YP_010377053.1;Note=F7R%3B similar to Vaccinia virus strain Copenhagen E8R;gbkey=CDS;gene_name=OPG070;locus_tag=NBT03_gp049;product=MPXVgp056;protein_id=YP_010377053.1 -NC_063383.1 RefSeq gene 51418 54438 . - . ID=gene-NBT03_gp050;Dbxref=GeneID:72551466;Name=OPG071;gbkey=Gene;gene_name=OPG071;gene_biotype=protein_coding;locus_tag=NBT03_gp050;old_locus_tag=MPXV-M5312_HM12_Rivers-055 -NC_063383.1 RefSeq CDS 51418 54438 . - 0 ID=cds-YP_010377054.1;Parent=gene-NBT03_gp050;Dbxref=Genbank:YP_010377054.1,GeneID:72551466;Name=YP_010377054.1;Note=F8L%3B similar to Vaccinia virus strain Copenhagen E9L%3B DNA polymerase%2C catalytic subunit;gbkey=CDS;gene_name=OPG071;locus_tag=NBT03_gp050;product=MPXVgp057;protein_id=YP_010377054.1 -NC_063383.1 RefSeq gene 54470 54757 . + . ID=gene-NBT03_gp051;Dbxref=GeneID:72551467;Name=OPG072;gbkey=Gene;gene_name=OPG072;gene_biotype=protein_coding;locus_tag=NBT03_gp051;old_locus_tag=MPXV-M5312_HM12_Rivers-056 -NC_063383.1 RefSeq CDS 54470 54757 . + 0 ID=cds-YP_010377055.1;Parent=gene-NBT03_gp051;Dbxref=Genbank:YP_010377055.1,GeneID:72551467;Name=YP_010377055.1;Note=F9R%3B similar to Vaccinia virus strain Copenhagen E10R%3B protein disulfide bond-forming enzyme;gbkey=CDS;gene_name=OPG072;locus_tag=NBT03_gp051;product=MPXVgp058;protein_id=YP_010377055.1 -NC_063383.1 RefSeq gene 54752 55141 . - . ID=gene-NBT03_gp052;Dbxref=GeneID:72551468;Name=NBT03_gp052;gbkey=Gene;gene_biotype=protein_coding;locus_tag=NBT03_gp052;old_locus_tag=MPXV-M5312_HM12_Rivers-057 -NC_063383.1 RefSeq CDS 54752 55141 . - 0 ID=cds-YP_010377056.1;Parent=gene-NBT03_gp052;Dbxref=Genbank:YP_010377056.1,GeneID:72551468;Name=YP_010377056.1;Note=F10L%3B similar to Vaccinia virus strain Copenhagen E11L%3B virion core protein;gbkey=CDS;locus_tag=NBT03_gp052;product=MPXVgp059;protein_id=YP_010377056.1 -NC_063383.1 RefSeq gene 55128 57125 . - . ID=gene-NBT03_gp053;Dbxref=GeneID:72551469;Name=OPG074;gbkey=Gene;gene_name=OPG074;gene_biotype=protein_coding;locus_tag=NBT03_gp053;old_locus_tag=MPXV-M5312_HM12_Rivers-058 -NC_063383.1 RefSeq CDS 55128 57125 . - 0 ID=cds-YP_010377057.1;Parent=gene-NBT03_gp053;Dbxref=Genbank:YP_010377057.1,GeneID:72551469;Name=YP_010377057.1;Note=Q1L%3B similar to Vaccinia virus strain Copenhagen O1L;gbkey=CDS;gene_name=OPG074;locus_tag=NBT03_gp053;product=MPXVgp060;protein_id=YP_010377057.1 -NC_063383.1 RefSeq gene 57172 57498 . - . ID=gene-NBT03_gp054;Dbxref=GeneID:72551470;Name=OPG075;gbkey=Gene;gene_name=OPG075;gene_biotype=protein_coding;locus_tag=NBT03_gp054;old_locus_tag=MPXV-M5312_HM12_Rivers-059 -NC_063383.1 RefSeq CDS 57172 57498 . - 0 ID=cds-YP_010377058.1;Parent=gene-NBT03_gp054;Dbxref=Genbank:YP_010377058.1,GeneID:72551470;Name=YP_010377058.1;Note=Q2L%3B similar to Vaccinia virus strain Copenhagen O2L%3B virion-associated glutaredoxin;gbkey=CDS;gene_name=OPG075;locus_tag=NBT03_gp054;product=MPXVgp061;protein_id=YP_010377058.1 -NC_063383.1 RefSeq gene 57523 57630 . - . ID=gene-NBT03_gp055;Dbxref=GeneID:72551471;Name=OPG076;gbkey=Gene;gene_name=OPG076;gene_biotype=protein_coding;locus_tag=NBT03_gp055 -NC_063383.1 RefSeq CDS 57523 57630 . - 0 ID=cds-YP_010377183.1;Parent=gene-NBT03_gp055;Dbxref=Genbank:YP_010377183.1,GeneID:72551471;Name=YP_010377183.1;gbkey=CDS;gene_name=OPG076;locus_tag=NBT03_gp055;product=MV membrane%2C EFC component;protein_id=YP_010377183.1 -NC_063383.1 RefSeq gene 57645 58583 . - . ID=gene-NBT03_gp056;Dbxref=GeneID:72551472;Name=OPG077;gbkey=Gene;gene_name=OPG077;gene_biotype=protein_coding;locus_tag=NBT03_gp056;old_locus_tag=MPXV-M5312_HM12_Rivers-060 -NC_063383.1 RefSeq CDS 57645 58583 . - 0 ID=cds-YP_010377059.1;Parent=gene-NBT03_gp056;Dbxref=Genbank:YP_010377059.1,GeneID:72551472;Name=YP_010377059.1;Note=I1L%3B similar to Vaccinia virus strain Copenhagen I1L%3B virosomal protein essential for virus multiplication;gbkey=CDS;gene_name=OPG077;locus_tag=NBT03_gp056;product=MPXVgp062;protein_id=YP_010377059.1 -NC_063383.1 RefSeq gene 58590 58811 . - . ID=gene-NBT03_gp057;Dbxref=GeneID:72551473;Name=OPG078;gbkey=Gene;gene_name=OPG078;gene_biotype=protein_coding;locus_tag=NBT03_gp057;old_locus_tag=MPXV-M5312_HM12_Rivers-061 -NC_063383.1 RefSeq CDS 58590 58811 . - 0 ID=cds-YP_010377060.1;Parent=gene-NBT03_gp057;Dbxref=Genbank:YP_010377060.1,GeneID:72551473;Name=YP_010377060.1;Note=I2L%3B similar to Vaccinia virus strain Copenhagen I2L;gbkey=CDS;gene_name=OPG078;locus_tag=NBT03_gp057;product=MPXVgp063;protein_id=YP_010377060.1 -NC_063383.1 RefSeq gene 58812 59621 . - . ID=gene-NBT03_gp058;Dbxref=GeneID:72551474;Name=OPG079;gbkey=Gene;gene_name=OPG079;gene_biotype=protein_coding;locus_tag=NBT03_gp058;old_locus_tag=MPXV-M5312_HM12_Rivers-062 -NC_063383.1 RefSeq CDS 58812 59621 . - 0 ID=cds-YP_010377061.1;Parent=gene-NBT03_gp058;Dbxref=Genbank:YP_010377061.1,GeneID:72551474;Name=YP_010377061.1;Note=I3L%3B similar to Vaccinia virus strain Copenhagen I3L%3B virosomal ssDNA-binding phosphoprotein%3B interacts with R2 subunit of ribonucleotide reductase;gbkey=CDS;gene_name=OPG079;locus_tag=NBT03_gp058;product=MPXVgp064;protein_id=YP_010377061.1 -NC_063383.1 RefSeq gene 59703 62018 . - . ID=gene-NBT03_gp059;Dbxref=GeneID:72551475;Name=OPG080;gbkey=Gene;gene_name=OPG080;gene_biotype=protein_coding;locus_tag=NBT03_gp059;old_locus_tag=MPXV-M5312_HM12_Rivers-063 -NC_063383.1 RefSeq CDS 59703 62018 . - 0 ID=cds-YP_010377062.1;Parent=gene-NBT03_gp059;Dbxref=Genbank:YP_010377062.1,GeneID:72551475;Name=YP_010377062.1;Note=I4L%3B similar to Vaccinia virus strain Copenhagen I4L%3B ribonucleotide reductase%2C large subunit%2C R1;gbkey=CDS;gene_name=OPG080;locus_tag=NBT03_gp059;product=MPXVgp065;protein_id=YP_010377062.1 -NC_063383.1 RefSeq gene 62046 62285 . - . ID=gene-NBT03_gp060;Dbxref=GeneID:72551476;Name=OPG081;gbkey=Gene;gene_name=OPG081;gene_biotype=protein_coding;locus_tag=NBT03_gp060;old_locus_tag=MPXV-M5312_HM12_Rivers-064 -NC_063383.1 RefSeq CDS 62046 62285 . - 0 ID=cds-YP_010377063.1;Parent=gene-NBT03_gp060;Dbxref=Genbank:YP_010377063.1,GeneID:72551476;Name=YP_010377063.1;Note=I5L%3B similar to Vaccinia virus strain Copenhagen I5L%3B IMV surface membrane protein;gbkey=CDS;gene_name=OPG081;locus_tag=NBT03_gp060;product=MPXVgp066;protein_id=YP_010377063.1 -NC_063383.1 RefSeq gene 62304 63452 . - . ID=gene-NBT03_gp061;Dbxref=GeneID:72551477;Name=OPG082;gbkey=Gene;gene_name=OPG082;gene_biotype=protein_coding;locus_tag=NBT03_gp061;old_locus_tag=MPXV-M5312_HM12_Rivers-065 -NC_063383.1 RefSeq CDS 62304 63452 . - 0 ID=cds-YP_010377064.1;Parent=gene-NBT03_gp061;Dbxref=Genbank:YP_010377064.1,GeneID:72551477;Name=YP_010377064.1;Note=I6L%3B similar to Vaccinia virus strain Copenhagen I6L;gbkey=CDS;gene_name=OPG082;locus_tag=NBT03_gp061;product=MPXVgp067;protein_id=YP_010377064.1 -NC_063383.1 RefSeq gene 63445 64716 . - . ID=gene-NBT03_gp062;Dbxref=GeneID:72551478;Name=OPG083;gbkey=Gene;gene_name=OPG083;gene_biotype=protein_coding;locus_tag=NBT03_gp062;old_locus_tag=MPXV-M5312_HM12_Rivers-066 -NC_063383.1 RefSeq CDS 63445 64716 . - 0 ID=cds-YP_010377065.1;Parent=gene-NBT03_gp062;Dbxref=Genbank:YP_010377065.1,GeneID:72551478;Name=YP_010377065.1;Note=I7L%3B similar to Vaccinia virus strain Copenhagen I7L%3B virion core protein%3B similar to DNA topoisomerase II;gbkey=CDS;gene_name=OPG083;locus_tag=NBT03_gp062;product=MPXVgp068;protein_id=YP_010377065.1 -NC_063383.1 RefSeq gene 64722 66752 . + . ID=gene-NBT03_gp063;Dbxref=GeneID:72551479;Name=OPG084;gbkey=Gene;gene_name=OPG084;gene_biotype=protein_coding;locus_tag=NBT03_gp063;old_locus_tag=MPXV-M5312_HM12_Rivers-067 -NC_063383.1 RefSeq CDS 64722 66752 . + 0 ID=cds-YP_010377066.1;Parent=gene-NBT03_gp063;Dbxref=Genbank:YP_010377066.1,GeneID:72551479;Name=YP_010377066.1;Note=I8R%3B similar to Vaccinia virus strain Copenhagen I8R%3B nucleoside triphosphate phosphohydrolase II%2C NPH-II%3B DNA and RNA helicase;gbkey=CDS;gene_name=OPG084;locus_tag=NBT03_gp063;product=MPXVgp069;protein_id=YP_010377066.1 -NC_063383.1 RefSeq gene 66756 68531 . - . ID=gene-NBT03_gp064;Dbxref=GeneID:72551480;Name=OPG085;gbkey=Gene;gene_name=OPG085;gene_biotype=protein_coding;locus_tag=NBT03_gp064;old_locus_tag=MPXV-M5312_HM12_Rivers-068 -NC_063383.1 RefSeq CDS 66756 68531 . - 0 ID=cds-YP_010377067.1;Parent=gene-NBT03_gp064;Dbxref=Genbank:YP_010377067.1,GeneID:72551480;Name=YP_010377067.1;Note=G1L%3B similar to Vaccinia virus strain Copenhagen G1L%3B proteinase;gbkey=CDS;gene_name=OPG085;locus_tag=NBT03_gp064;product=MPXVgp070;protein_id=YP_010377067.1 -NC_063383.1 RefSeq gene 68528 68863 . - . ID=gene-NBT03_gp065;Dbxref=GeneID:72551481;Name=OPG086;gbkey=Gene;gene_name=OPG086;gene_biotype=protein_coding;locus_tag=NBT03_gp065;old_locus_tag=MPXV-M5312_HM12_Rivers-069 -NC_063383.1 RefSeq CDS 68528 68863 . - 0 ID=cds-YP_010377068.1;Parent=gene-NBT03_gp065;Dbxref=Genbank:YP_010377068.1,GeneID:72551481;Name=YP_010377068.1;Note=G2L%3B similar to Vaccinia virus strain Copenhagen G3L;gbkey=CDS;gene_name=OPG086;locus_tag=NBT03_gp065;product=MPXVgp071;protein_id=YP_010377068.1 -NC_063383.1 RefSeq gene 68857 69519 . + . ID=gene-NBT03_gp066;Dbxref=GeneID:72551482;Name=OPG087;gbkey=Gene;gene_name=OPG087;gene_biotype=protein_coding;locus_tag=NBT03_gp066;old_locus_tag=MPXV-M5312_HM12_Rivers-070 -NC_063383.1 RefSeq CDS 68857 69519 . + 0 ID=cds-YP_010377069.1;Parent=gene-NBT03_gp066;Dbxref=Genbank:YP_010377069.1,GeneID:72551482;Name=YP_010377069.1;Note=G3R%3B similar to Vaccinia virus strain Copenhagen G2R;gbkey=CDS;gene_name=OPG087;locus_tag=NBT03_gp066;product=MPXVgp072;protein_id=YP_010377069.1 -NC_063383.1 RefSeq gene 69489 69863 . - . ID=gene-NBT03_gp067;Dbxref=GeneID:72551483;Name=OPG088;gbkey=Gene;gene_name=OPG088;gene_biotype=protein_coding;locus_tag=NBT03_gp067;old_locus_tag=MPXV-M5312_HM12_Rivers-071 -NC_063383.1 RefSeq CDS 69489 69863 . - 0 ID=cds-YP_010377070.1;Parent=gene-NBT03_gp067;Dbxref=Genbank:YP_010377070.1,GeneID:72551483;Name=YP_010377070.1;Note=G4L%3B similar to Vaccinia virus strain Copenhagen G4L%3B virion-associated glutaredoxin;gbkey=CDS;gene_name=OPG088;locus_tag=NBT03_gp067;product=MPXVgp073;protein_id=YP_010377070.1 -NC_063383.1 RefSeq gene 69866 71170 . + . ID=gene-NBT03_gp068;Dbxref=GeneID:72551484;Name=OPG089;gbkey=Gene;gene_name=OPG089;gene_biotype=protein_coding;locus_tag=NBT03_gp068;old_locus_tag=MPXV-M5312_HM12_Rivers-072 -NC_063383.1 RefSeq CDS 69866 71170 . + 0 ID=cds-YP_010377071.1;Parent=gene-NBT03_gp068;Dbxref=Genbank:YP_010377071.1,GeneID:72551484;Name=YP_010377071.1;Note=G5R%3B similar to Vaccinia virus strain Copenhagen G5R;gbkey=CDS;gene_name=OPG089;locus_tag=NBT03_gp068;product=MPXVgp074;protein_id=YP_010377071.1 -NC_063383.1 RefSeq gene 71179 71370 . + . ID=gene-NBT03_gp069;Dbxref=GeneID:72551485;Name=OPG090;gbkey=Gene;gene_name=OPG090;gene_biotype=protein_coding;locus_tag=NBT03_gp069;old_locus_tag=MPXV-M5312_HM12_Rivers-073 -NC_063383.1 RefSeq CDS 71179 71370 . + 0 ID=cds-YP_010377072.1;Parent=gene-NBT03_gp069;Dbxref=Genbank:YP_010377072.1,GeneID:72551485;Name=YP_010377072.1;Note=G6R%3B RNA polymerase%2C 7 kDa subunit;gbkey=CDS;gene_name=OPG090;locus_tag=NBT03_gp069;product=MPXVgp075;protein_id=YP_010377072.1 -NC_063383.1 RefSeq gene 71370 71867 . + . ID=gene-NBT03_gp070;Dbxref=GeneID:72551486;Name=OPG091;gbkey=Gene;gene_name=OPG091;gene_biotype=protein_coding;locus_tag=NBT03_gp070;old_locus_tag=MPXV-M5312_HM12_Rivers-074 -NC_063383.1 RefSeq CDS 71370 71867 . + 0 ID=cds-YP_010377073.1;Parent=gene-NBT03_gp070;Dbxref=Genbank:YP_010377073.1,GeneID:72551486;Name=YP_010377073.1;Note=G7R%3B similar to Vaccinia virus strain Copenhagen G6R;gbkey=CDS;gene_name=OPG091;locus_tag=NBT03_gp070;product=MPXVgp076;protein_id=YP_010377073.1 -NC_063383.1 RefSeq gene 71832 72947 . - . ID=gene-NBT03_gp071;Dbxref=GeneID:72551487;Name=OPG092;gbkey=Gene;gene_name=OPG092;gene_biotype=protein_coding;locus_tag=NBT03_gp071;old_locus_tag=MPXV-M5312_HM12_Rivers-075 -NC_063383.1 RefSeq CDS 71832 72947 . - 0 ID=cds-YP_010377074.1;Parent=gene-NBT03_gp071;Dbxref=Genbank:YP_010377074.1,GeneID:72551487;Name=YP_010377074.1;Note=G8L%3B similar to Vaccinia virus strain Copenhagen G7L%3B virion protein;gbkey=CDS;gene_name=OPG092;locus_tag=NBT03_gp071;product=MPXVgp077;protein_id=YP_010377074.1 -NC_063383.1 RefSeq gene 72978 73760 . + . ID=gene-NBT03_gp072;Dbxref=GeneID:72551488;Name=OPG093;gbkey=Gene;gene_name=OPG093;gene_biotype=protein_coding;locus_tag=NBT03_gp072;old_locus_tag=MPXV-M5312_HM12_Rivers-076 -NC_063383.1 RefSeq CDS 72978 73760 . + 0 ID=cds-YP_010377075.1;Parent=gene-NBT03_gp072;Dbxref=Genbank:YP_010377075.1,GeneID:72551488;Name=YP_010377075.1;Note=G9R%3B similar to Vaccinia virus strain Copenhagen G8R%3B late gene transcription factor%2C VLTF-1;gbkey=CDS;gene_name=OPG093;locus_tag=NBT03_gp072;product=MPXVgp078;protein_id=YP_010377075.1 -NC_063383.1 RefSeq gene 73780 74802 . + . ID=gene-NBT03_gp073;Dbxref=GeneID:72551489;Name=OPG094;gbkey=Gene;gene_name=OPG094;gene_biotype=protein_coding;locus_tag=NBT03_gp073;old_locus_tag=MPXV-M5312_HM12_Rivers-077 -NC_063383.1 RefSeq CDS 73780 74802 . + 0 ID=cds-YP_010377076.1;Parent=gene-NBT03_gp073;Dbxref=Genbank:YP_010377076.1,GeneID:72551489;Name=YP_010377076.1;Note=G10R%3B similar to Vaccinia virus strain Copenhagen G9R%3B myristylated protein;gbkey=CDS;gene_name=OPG094;locus_tag=NBT03_gp073;product=MPXVgp079;protein_id=YP_010377076.1 -NC_063383.1 RefSeq gene 74803 75555 . + . ID=gene-NBT03_gp074;Dbxref=GeneID:72551490;Name=OPG095;gbkey=Gene;gene_name=OPG095;gene_biotype=protein_coding;locus_tag=NBT03_gp074;old_locus_tag=MPXV-M5312_HM12_Rivers-078 -NC_063383.1 RefSeq CDS 74803 75555 . + 0 ID=cds-YP_010377077.1;Parent=gene-NBT03_gp074;Dbxref=Genbank:YP_010377077.1,GeneID:72551490;Name=YP_010377077.1;Note=M1R%3B similar to Vaccinia virus strain Copenhagen L1R%3B myristylated IMV surface membrane protein;gbkey=CDS;gene_name=OPG095;locus_tag=NBT03_gp074;product=MPXVgp080;protein_id=YP_010377077.1 -NC_063383.1 RefSeq gene 75587 75865 . + . ID=gene-NBT03_gp075;Dbxref=GeneID:72551491;Name=OPG096;gbkey=Gene;gene_name=OPG096;gene_biotype=protein_coding;locus_tag=NBT03_gp075;old_locus_tag=MPXV-M5312_HM12_Rivers-079 -NC_063383.1 RefSeq CDS 75587 75865 . + 0 ID=cds-YP_010377078.1;Parent=gene-NBT03_gp075;Dbxref=Genbank:YP_010377078.1,GeneID:72551491;Name=YP_010377078.1;Note=M2R%3B similar to Vaccinia virus strain Copenhagen L2R;gbkey=CDS;gene_name=OPG096;locus_tag=NBT03_gp075;product=MPXVgp081;protein_id=YP_010377078.1 -NC_063383.1 RefSeq gene 75841 76875 . - . ID=gene-NBT03_gp076;Dbxref=GeneID:72551492;Name=OPG097;gbkey=Gene;gene_name=OPG097;gene_biotype=protein_coding;locus_tag=NBT03_gp076;old_locus_tag=MPXV-M5312_HM12_Rivers-080 -NC_063383.1 RefSeq CDS 75841 76875 . - 0 ID=cds-YP_010377079.1;Parent=gene-NBT03_gp076;Dbxref=Genbank:YP_010377079.1,GeneID:72551492;Name=YP_010377079.1;Note=M3L%3B similar to Vaccinia virus strain Copenhagen L3L;gbkey=CDS;gene_name=OPG097;locus_tag=NBT03_gp076;product=MPXVgp082;protein_id=YP_010377079.1 -NC_063383.1 RefSeq gene 76900 77655 . + . ID=gene-NBT03_gp077;Dbxref=GeneID:72551493;Name=OPG098;gbkey=Gene;gene_name=OPG098;gene_biotype=protein_coding;locus_tag=NBT03_gp077;old_locus_tag=MPXV-M5312_HM12_Rivers-081 -NC_063383.1 RefSeq CDS 76900 77655 . + 0 ID=cds-YP_010377080.1;Parent=gene-NBT03_gp077;Dbxref=Genbank:YP_010377080.1,GeneID:72551493;Name=YP_010377080.1;Note=M4R%3B similar to Vaccinia virus strain Copenhagen L4R%3B virion core protein%3B ssDNA binding%3B stimulation of I8R helicase activity;gbkey=CDS;gene_name=OPG098;locus_tag=NBT03_gp077;product=MPXVgp083;protein_id=YP_010377080.1 -NC_063383.1 RefSeq gene 77665 78051 . + . ID=gene-NBT03_gp078;Dbxref=GeneID:72551494;Name=OPG099;gbkey=Gene;gene_name=OPG099;gene_biotype=protein_coding;locus_tag=NBT03_gp078;old_locus_tag=MPXV-M5312_HM12_Rivers-082 -NC_063383.1 RefSeq CDS 77665 78051 . + 0 ID=cds-YP_010377081.1;Parent=gene-NBT03_gp078;Dbxref=Genbank:YP_010377081.1,GeneID:72551494;Name=YP_010377081.1;Note=M5R%3B similar to Vaccinia virus strain Copenhagen L5R;gbkey=CDS;gene_name=OPG099;locus_tag=NBT03_gp078;product=MPXVgp084;protein_id=YP_010377081.1 -NC_063383.1 RefSeq gene 78008 78466 . + . ID=gene-NBT03_gp079;Dbxref=GeneID:72551495;Name=OPG100;gbkey=Gene;gene_name=OPG100;gene_biotype=protein_coding;locus_tag=NBT03_gp079;old_locus_tag=MPXV-M5312_HM12_Rivers-083 -NC_063383.1 RefSeq CDS 78008 78466 . + 0 ID=cds-YP_010377082.1;Parent=gene-NBT03_gp079;Dbxref=Genbank:YP_010377082.1,GeneID:72551495;Name=YP_010377082.1;Note=L1R%3B similar to Vaccinia virus strain Copenhagen J1R;gbkey=CDS;gene_name=OPG100;locus_tag=NBT03_gp079;product=MPXVgp085;protein_id=YP_010377082.1 -NC_063383.1 RefSeq gene 78486 79019 . + . ID=gene-NBT03_gp080;Dbxref=GeneID:72551496;Name=OPG101;gbkey=Gene;gene_name=OPG101;gene_biotype=protein_coding;locus_tag=NBT03_gp080;old_locus_tag=MPXV-M5312_HM12_Rivers-084 -NC_063383.1 RefSeq CDS 78486 79019 . + 0 ID=cds-YP_010377083.1;Parent=gene-NBT03_gp080;Dbxref=Genbank:YP_010377083.1,GeneID:72551496;Name=YP_010377083.1;Note=L2R%3B similar to Vaccinia virus strain Copenhagen J2R%3B thymidine kinase;gbkey=CDS;gene_name=OPG101;locus_tag=NBT03_gp080;product=MPXVgp086;protein_id=YP_010377083.1 -NC_063383.1 RefSeq gene 79085 80086 . + . ID=gene-NBT03_gp081;Dbxref=GeneID:72551497;Name=OPG102;gbkey=Gene;gene_name=OPG102;gene_biotype=protein_coding;locus_tag=NBT03_gp081;old_locus_tag=MPXV-M5312_HM12_Rivers-085 -NC_063383.1 RefSeq CDS 79085 80086 . + 0 ID=cds-YP_010377084.1;Parent=gene-NBT03_gp081;Dbxref=Genbank:YP_010377084.1,GeneID:72551497;Name=YP_010377084.1;Note=L3R%3B similar to Vaccinia virus strain Copenhagen J3R%3B poly-A polymerase%2C stimulatory subunit%2C simultaneously cap-specific mRNA (nucleoside-O2'-)-methyltransferase;gbkey=CDS;gene_name=OPG102;locus_tag=NBT03_gp081;product=MPXVgp087;protein_id=YP_010377084.1 -NC_063383.1 RefSeq gene 80001 80558 . + . ID=gene-NBT03_gp082;Dbxref=GeneID:72551498;Name=OPG103;gbkey=Gene;gene_name=OPG103;gene_biotype=protein_coding;locus_tag=NBT03_gp082;old_locus_tag=MPXV-M5312_HM12_Rivers-086 -NC_063383.1 RefSeq CDS 80001 80558 . + 0 ID=cds-YP_010377085.1;Parent=gene-NBT03_gp082;Dbxref=Genbank:YP_010377085.1,GeneID:72551498;Name=YP_010377085.1;Note=L4R%3B similar to Vaccinia virus strain Copenhagen J4R%3B RNA polymerase%2C 22 kDa subunit;gbkey=CDS;gene_name=OPG103;locus_tag=NBT03_gp082;product=MPXVgp088;protein_id=YP_010377085.1 -NC_063383.1 RefSeq gene 80618 81019 . - . ID=gene-NBT03_gp083;Dbxref=GeneID:72551499;Name=OPG104;gbkey=Gene;gene_name=OPG104;gene_biotype=protein_coding;locus_tag=NBT03_gp083;old_locus_tag=MPXV-M5312_HM12_Rivers-087 -NC_063383.1 RefSeq CDS 80618 81019 . - 0 ID=cds-YP_010377086.1;Parent=gene-NBT03_gp083;Dbxref=Genbank:YP_010377086.1,GeneID:72551499;Name=YP_010377086.1;Note=L5L%3B similar to Vaccinia virus strain Copenhagen J5L%3B essential for virus multiplication;gbkey=CDS;gene_name=OPG104;locus_tag=NBT03_gp083;product=MPXVgp089;protein_id=YP_010377086.1 -NC_063383.1 RefSeq gene 81126 84986 . + . ID=gene-NBT03_gp084;Dbxref=GeneID:72551500;Name=OPG105;gbkey=Gene;gene_name=OPG105;gene_biotype=protein_coding;locus_tag=NBT03_gp084;old_locus_tag=MPXV-M5312_HM12_Rivers-088 -NC_063383.1 RefSeq CDS 81126 84986 . + 0 ID=cds-YP_010377087.1;Parent=gene-NBT03_gp084;Dbxref=Genbank:YP_010377087.1,GeneID:72551500;Name=YP_010377087.1;Note=L6R%3B similar to Vaccinia virus strain Copenhagen J6R%3B RNA polymerase%2C 147 kDa subunit;gbkey=CDS;gene_name=OPG105;locus_tag=NBT03_gp084;product=MPXVgp090;protein_id=YP_010377087.1 -NC_063383.1 RefSeq gene 84983 85498 . - . ID=gene-NBT03_gp085;Dbxref=GeneID:72551501;Name=OPG106;gbkey=Gene;gene_name=OPG106;gene_biotype=protein_coding;locus_tag=NBT03_gp085;old_locus_tag=MPXV-M5312_HM12_Rivers-089 -NC_063383.1 RefSeq CDS 84983 85498 . - 0 ID=cds-YP_010377088.1;Parent=gene-NBT03_gp085;Dbxref=Genbank:YP_010377088.1,GeneID:72551501;Name=YP_010377088.1;Note=H1L%3B similar to Vaccinia virus strain Copenhagen H1L%3B tyrosine;gbkey=CDS;gene_name=OPG106;locus_tag=NBT03_gp085;product=MPXVgp091;protein_id=YP_010377088.1 -NC_063383.1 RefSeq gene 85512 86081 . + . ID=gene-NBT03_gp086;Dbxref=GeneID:72551502;Name=OPG107;gbkey=Gene;gene_name=OPG107;gene_biotype=protein_coding;locus_tag=NBT03_gp086;old_locus_tag=MPXV-M5312_HM12_Rivers-090 -NC_063383.1 RefSeq CDS 85512 86081 . + 0 ID=cds-YP_010377089.1;Parent=gene-NBT03_gp086;Dbxref=Genbank:YP_010377089.1,GeneID:72551502;Name=YP_010377089.1;Note=H2R%3B similar to Vaccinia virus strain Copenhagen H2R;gbkey=CDS;gene_name=OPG107;locus_tag=NBT03_gp086;product=MPXVgp092;protein_id=YP_010377089.1 -NC_063383.1 RefSeq gene 86085 87059 . - . ID=gene-NBT03_gp087;Dbxref=GeneID:72551503;Name=OPG108;gbkey=Gene;gene_name=OPG108;gene_biotype=protein_coding;locus_tag=NBT03_gp087;old_locus_tag=MPXV-M5312_HM12_Rivers-091 -NC_063383.1 RefSeq CDS 86085 87059 . - 0 ID=cds-YP_010377090.1;Parent=gene-NBT03_gp087;Dbxref=Genbank:YP_010377090.1,GeneID:72551503;Name=YP_010377090.1;Note=H3L%3B similar to Vaccinia virus strain Copenhagen H3L%3B IMV surface membrane protein;gbkey=CDS;gene_name=OPG108;locus_tag=NBT03_gp087;product=MPXVgp093;protein_id=YP_010377090.1 -NC_063383.1 RefSeq gene 87060 89447 . - . ID=gene-NBT03_gp088;Dbxref=GeneID:72551504;Name=OPG109;gbkey=Gene;gene_name=OPG109;gene_biotype=protein_coding;locus_tag=NBT03_gp088;old_locus_tag=MPXV-M5312_HM12_Rivers-092 -NC_063383.1 RefSeq CDS 87060 89447 . - 0 ID=cds-YP_010377091.1;Parent=gene-NBT03_gp088;Dbxref=Genbank:YP_010377091.1,GeneID:72551504;Name=YP_010377091.1;Note=H4L%3B similar to Vaccinia virus strain Copenhagen H4L%3B virion core RNA polymerase-associated protein%2C RAP94;gbkey=CDS;gene_name=OPG109;locus_tag=NBT03_gp088;product=MPXVgp094;protein_id=YP_010377091.1 -NC_063383.1 RefSeq gene 89632 90264 . + . ID=gene-NBT03_gp089;Dbxref=GeneID:72551505;Name=OPG110;gbkey=Gene;gene_name=OPG110;gene_biotype=protein_coding;locus_tag=NBT03_gp089;old_locus_tag=MPXV-M5312_HM12_Rivers-093 -NC_063383.1 RefSeq CDS 89632 90264 . + 0 ID=cds-YP_010377092.1;Parent=gene-NBT03_gp089;Dbxref=Genbank:YP_010377092.1,GeneID:72551505;Name=YP_010377092.1;Note=H5R%3B similar to Vaccinia virus strain Copenhagen H5R%3B virosome-associated late gene transcription factor%2C VLTF-4%3B Ca2+-binding motif;gbkey=CDS;gene_name=OPG110;locus_tag=NBT03_gp089;product=MPXVgp095;protein_id=YP_010377092.1 -NC_063383.1 RefSeq gene 90265 91209 . + . ID=gene-NBT03_gp090;Dbxref=GeneID:72551506;Name=OPG111;gbkey=Gene;gene_name=OPG111;gene_biotype=protein_coding;locus_tag=NBT03_gp090;old_locus_tag=MPXV-M5312_HM12_Rivers-094 -NC_063383.1 RefSeq CDS 90265 91209 . + 0 ID=cds-YP_010377093.1;Parent=gene-NBT03_gp090;Dbxref=Genbank:YP_010377093.1,GeneID:72551506;Name=YP_010377093.1;Note=H6R%3B similar to Vaccinia virus strain Copenhagen H6R%3B DNA topoisomerase;gbkey=CDS;gene_name=OPG111;locus_tag=NBT03_gp090;product=MPXVgp096;protein_id=YP_010377093.1 -NC_063383.1 RefSeq gene 91247 91687 . + . ID=gene-NBT03_gp091;Dbxref=GeneID:72551507;Name=OPG112;gbkey=Gene;gene_name=OPG112;gene_biotype=protein_coding;locus_tag=NBT03_gp091;old_locus_tag=MPXV-M5312_HM12_Rivers-095 -NC_063383.1 RefSeq CDS 91247 91687 . + 0 ID=cds-YP_010377094.1;Parent=gene-NBT03_gp091;Dbxref=Genbank:YP_010377094.1,GeneID:72551507;Name=YP_010377094.1;Note=H7R%3B similar to Vaccinia virus strain Copenhagen H7R;gbkey=CDS;gene_name=OPG112;locus_tag=NBT03_gp091;product=MPXVgp097;protein_id=YP_010377094.1 -NC_063383.1 RefSeq gene 91731 94268 . + . ID=gene-NBT03_gp092;Dbxref=GeneID:72551508;Name=OPG113;gbkey=Gene;gene_name=OPG113;gene_biotype=protein_coding;locus_tag=NBT03_gp092;old_locus_tag=MPXV-M5312_HM12_Rivers-096 -NC_063383.1 RefSeq CDS 91731 94268 . + 0 ID=cds-YP_010377095.1;Parent=gene-NBT03_gp092;Dbxref=Genbank:YP_010377095.1,GeneID:72551508;Name=YP_010377095.1;Note=E1R%3B similar to Vaccinia virus strain Copenhagen D1R%3B mRNA capping enzyme%2C large subunit%3B RNA 5' triphosphatase and RNA guanylyl transferase activities;gbkey=CDS;gene_name=OPG113;locus_tag=NBT03_gp092;product=MPXVgp098;protein_id=YP_010377095.1 -NC_063383.1 RefSeq gene 94227 94667 . - . ID=gene-NBT03_gp093;Dbxref=GeneID:72551509;Name=OPG114;gbkey=Gene;gene_name=OPG114;gene_biotype=protein_coding;locus_tag=NBT03_gp093;old_locus_tag=MPXV-M5312_HM12_Rivers-097 -NC_063383.1 RefSeq CDS 94227 94667 . - 0 ID=cds-YP_010377096.1;Parent=gene-NBT03_gp093;Dbxref=Genbank:YP_010377096.1,GeneID:72551509;Name=YP_010377096.1;Note=E2L%3B similar to Vaccinia virus strain Copenhagen D2L%3B virion core protein;gbkey=CDS;gene_name=OPG114;locus_tag=NBT03_gp093;product=MPXVgp099;protein_id=YP_010377096.1 -NC_063383.1 RefSeq gene 94660 95361 . + . ID=gene-NBT03_gp094;Dbxref=GeneID:72551510;Name=OPG115;gbkey=Gene;gene_name=OPG115;gene_biotype=protein_coding;locus_tag=NBT03_gp094;old_locus_tag=MPXV-M5312_HM12_Rivers-098 -NC_063383.1 RefSeq CDS 94660 95361 . + 0 ID=cds-YP_010377097.1;Parent=gene-NBT03_gp094;Dbxref=Genbank:YP_010377097.1,GeneID:72551510;Name=YP_010377097.1;Note=E3R%3B similar to Vaccinia virus strain Copenhagen D3R%3B virion core protein;gbkey=CDS;gene_name=OPG115;locus_tag=NBT03_gp094;product=MPXVgp100;protein_id=YP_010377097.1 -NC_063383.1 RefSeq gene 95361 96017 . + . ID=gene-NBT03_gp095;Dbxref=GeneID:72551511;Name=OPG116;gbkey=Gene;gene_name=OPG116;gene_biotype=protein_coding;locus_tag=NBT03_gp095;old_locus_tag=MPXV-M5312_HM12_Rivers-099 -NC_063383.1 RefSeq CDS 95361 96017 . + 0 ID=cds-YP_010377098.1;Parent=gene-NBT03_gp095;Dbxref=Genbank:YP_010377098.1,GeneID:72551511;Name=YP_010377098.1;Note=E4R%3B similar to Vaccinia virus strain Copenhagen D4R%3B uracil DNA glycosylase;gbkey=CDS;gene_name=OPG116;locus_tag=NBT03_gp095;product=MPXVgp101;protein_id=YP_010377098.1 -NC_063383.1 RefSeq gene 96049 98406 . + . ID=gene-NBT03_gp096;Dbxref=GeneID:72551512;Name=OPG117;gbkey=Gene;gene_name=OPG117;gene_biotype=protein_coding;locus_tag=NBT03_gp096;old_locus_tag=MPXV-M5312_HM12_Rivers-100 -NC_063383.1 RefSeq CDS 96049 98406 . + 0 ID=cds-YP_010377099.1;Parent=gene-NBT03_gp096;Dbxref=Genbank:YP_010377099.1,GeneID:72551512;Name=YP_010377099.1;Note=E5R%3B similar to Vaccinia virus strain Copenhagen D5R%3B nucleic acid-independent nucleoside triphosphatase;gbkey=CDS;gene_name=OPG117;locus_tag=NBT03_gp096;product=MPXVgp102;protein_id=YP_010377099.1 -NC_063383.1 RefSeq gene 98446 100359 . + . ID=gene-NBT03_gp097;Dbxref=GeneID:72551513;Name=OPG118;gbkey=Gene;gene_name=OPG118;gene_biotype=protein_coding;locus_tag=NBT03_gp097;old_locus_tag=MPXV-M5312_HM12_Rivers-101 -NC_063383.1 RefSeq CDS 98446 100359 . + 0 ID=cds-YP_010377100.1;Parent=gene-NBT03_gp097;Dbxref=Genbank:YP_010377100.1,GeneID:72551513;Name=YP_010377100.1;Note=E6R%3B similar to Vaccinia virus strain Copenhagen D6R%3B early transcription factor%2C VETF%2C small subunit;gbkey=CDS;gene_name=OPG118;locus_tag=NBT03_gp097;product=MPXVgp103;protein_id=YP_010377100.1 -NC_063383.1 RefSeq gene 100386 100871 . + . ID=gene-NBT03_gp098;Dbxref=GeneID:72551514;Name=OPG119;gbkey=Gene;gene_name=OPG119;gene_biotype=protein_coding;locus_tag=NBT03_gp098;old_locus_tag=MPXV-M5312_HM12_Rivers-102 -NC_063383.1 RefSeq CDS 100386 100871 . + 0 ID=cds-YP_010377101.1;Parent=gene-NBT03_gp098;Dbxref=Genbank:YP_010377101.1,GeneID:72551514;Name=YP_010377101.1;Note=E7R%3B similar to Vaccinia virus strain Copenhagen D7R%3B RNA polymerase%2C 18 kDa subunit;gbkey=CDS;gene_name=OPG119;locus_tag=NBT03_gp098;product=MPXVgp104;protein_id=YP_010377101.1 -NC_063383.1 RefSeq gene 100834 101748 . - . ID=gene-NBT03_gp099;Dbxref=GeneID:72551515;Name=OPG120;gbkey=Gene;gene_name=OPG120;gene_biotype=protein_coding;locus_tag=NBT03_gp099;old_locus_tag=MPXV-M5312_HM12_Rivers-103 -NC_063383.1 RefSeq CDS 100834 101748 . - 0 ID=cds-YP_010377102.1;Parent=gene-NBT03_gp099;Dbxref=Genbank:YP_010377102.1,GeneID:72551515;Name=YP_010377102.1;Note=E8L%3B similar to Vaccinia virus strain Copenhagen D8L%3B IMV surface membrane 32 kDa protein%3B binding to cell surface chondroitin sulfate%3B IMV adsorption to cell surface;gbkey=CDS;gene_name=OPG120;locus_tag=NBT03_gp099;product=MPXVgp105;protein_id=YP_010377102.1 -NC_063383.1 RefSeq gene 101790 102431 . + . ID=gene-NBT03_gp100;Dbxref=GeneID:72551516;Name=OPG121;gbkey=Gene;gene_name=OPG121;gene_biotype=protein_coding;locus_tag=NBT03_gp100;old_locus_tag=MPXV-M5312_HM12_Rivers-104 -NC_063383.1 RefSeq CDS 101790 102431 . + 0 ID=cds-YP_010377103.1;Parent=gene-NBT03_gp100;Dbxref=Genbank:YP_010377103.1,GeneID:72551516;Name=YP_010377103.1;Note=E9R%3B similar to Vaccinia virus strain Copenhagen D9R%3B Mut-like;gbkey=CDS;gene_name=OPG121;locus_tag=NBT03_gp100;product=MPXVgp106;protein_id=YP_010377103.1 -NC_063383.1 RefSeq gene 102428 103174 . + . ID=gene-NBT03_gp101;Dbxref=GeneID:72551517;Name=OPG122;gbkey=Gene;gene_name=OPG122;gene_biotype=protein_coding;locus_tag=NBT03_gp101;old_locus_tag=MPXV-M5312_HM12_Rivers-105 -NC_063383.1 RefSeq CDS 102428 103174 . + 0 ID=cds-YP_010377104.1;Parent=gene-NBT03_gp101;Dbxref=Genbank:YP_010377104.1,GeneID:72551517;Name=YP_010377104.1;Note=E10R%3B similar to Vaccinia virus strain Copenhagen D10R%3B down regulation of gene expression%3B Mut-like;gbkey=CDS;gene_name=OPG122;locus_tag=NBT03_gp101;product=MPXVgp107;protein_id=YP_010377104.1 -NC_063383.1 RefSeq gene 103175 105070 . - . ID=gene-NBT03_gp102;Dbxref=GeneID:72551518;Name=OPG123;gbkey=Gene;gene_name=OPG123;gene_biotype=protein_coding;locus_tag=NBT03_gp102;old_locus_tag=MPXV-M5312_HM12_Rivers-106 -NC_063383.1 RefSeq CDS 103175 105070 . - 0 ID=cds-YP_010377105.1;Parent=gene-NBT03_gp102;Dbxref=Genbank:YP_010377105.1,GeneID:72551518;Name=YP_010377105.1;Note=E11L%3B similar to Vaccinia virus strain Copenhagen D11L%3B nucleoside triphosphate phosphohydrolase I%2C NPH I%3B DNA-dependent ATPase%3B early gene transcription termination factor;gbkey=CDS;gene_name=OPG123;locus_tag=NBT03_gp102;product=MPXVgp108;protein_id=YP_010377105.1 -NC_063383.1 RefSeq gene 105105 105968 . - . ID=gene-NBT03_gp103;Dbxref=GeneID:72551519;Name=OPG124;gbkey=Gene;gene_name=OPG124;gene_biotype=protein_coding;locus_tag=NBT03_gp103;old_locus_tag=MPXV-M5312_HM12_Rivers-107 -NC_063383.1 RefSeq CDS 105105 105968 . - 0 ID=cds-YP_010377106.1;Parent=gene-NBT03_gp103;Dbxref=Genbank:YP_010377106.1,GeneID:72551519;Name=YP_010377106.1;Note=E12L%3B similar to Vaccinia virus strain Copenhagen D12L%3B mRNA capping enzyme%2C small subunit%3B mRNA (guanine-N7-)-methyl-transferase%3B transcription initiation factor;gbkey=CDS;gene_name=OPG124;locus_tag=NBT03_gp103;product=MPXVgp109;protein_id=YP_010377106.1 -NC_063383.1 RefSeq gene 105999 107654 . - . ID=gene-NBT03_gp104;Dbxref=GeneID:72551520;Name=OPG125;gbkey=Gene;gene_name=OPG125;gene_biotype=protein_coding;locus_tag=NBT03_gp104;old_locus_tag=MPXV-M5312_HM12_Rivers-108 -NC_063383.1 RefSeq CDS 105999 107654 . - 0 ID=cds-YP_010377107.1;Parent=gene-NBT03_gp104;Dbxref=Genbank:YP_010377107.1,GeneID:72551520;Name=YP_010377107.1;Note=E13L%3B similar to Vaccinia virus strain Copenhagen D13L%3B protein needed for the formation of immature IMV surface membrane;gbkey=CDS;gene_name=OPG125;locus_tag=NBT03_gp104;product=MPXVgp110;protein_id=YP_010377107.1 -NC_063383.1 RefSeq gene 107678 108130 . - . ID=gene-NBT03_gp105;Dbxref=GeneID:72551521;Name=OPG126;gbkey=Gene;gene_name=OPG126;gene_biotype=protein_coding;locus_tag=NBT03_gp105;old_locus_tag=MPXV-M5312_HM12_Rivers-109 -NC_063383.1 RefSeq CDS 107678 108130 . - 0 ID=cds-YP_010377108.1;Parent=gene-NBT03_gp105;Dbxref=Genbank:YP_010377108.1,GeneID:72551521;Name=YP_010377108.1;Note=A1L%3B similar to Vaccinia virus strain Copenhagen A1L%3B late gene transcription factor%2C VLTF-2;gbkey=CDS;gene_name=OPG126;locus_tag=NBT03_gp105;product=MPXVgp111;protein_id=YP_010377108.1 -NC_063383.1 RefSeq gene 108151 108825 . - . ID=gene-NBT03_gp106;Dbxref=GeneID:72551522;Name=OPG127;gbkey=Gene;gene_name=OPG127;gene_biotype=protein_coding;locus_tag=NBT03_gp106;old_locus_tag=MPXV-M5312_HM12_Rivers-110 -NC_063383.1 RefSeq CDS 108151 108825 . - 0 ID=cds-YP_010377109.1;Parent=gene-NBT03_gp106;Dbxref=Genbank:YP_010377109.1,GeneID:72551522;Name=YP_010377109.1;Note=A2L%3B similar to Vaccinia virus strain Copenhagen A2L%3B late gene transcription factor%2C VLTF-3%3B zinc binding;gbkey=CDS;gene_name=OPG127;locus_tag=NBT03_gp106;product=MPXVgp112;protein_id=YP_010377109.1 -NC_063383.1 RefSeq gene 108822 109055 . - . ID=gene-NBT03_gp107;Dbxref=GeneID:72551523;Name=OPG128;gbkey=Gene;gene_name=OPG128;gene_biotype=protein_coding;locus_tag=NBT03_gp107;old_locus_tag=MPXV-M5312_HM12_Rivers-111 -NC_063383.1 RefSeq CDS 108822 109055 . - 0 ID=cds-YP_010377110.1;Parent=gene-NBT03_gp107;Dbxref=Genbank:YP_010377110.1,GeneID:72551523;Name=YP_010377110.1;Note=A3L;gbkey=CDS;gene_name=OPG128;locus_tag=NBT03_gp107;product=MPXVgp113;protein_id=YP_010377110.1 -NC_063383.1 RefSeq gene 109070 111004 . - . ID=gene-NBT03_gp108;Dbxref=GeneID:72551524;Name=OPG129;gbkey=Gene;gene_name=OPG129;gene_biotype=protein_coding;locus_tag=NBT03_gp108;old_locus_tag=MPXV-M5312_HM12_Rivers-112 -NC_063383.1 RefSeq CDS 109070 111004 . - 0 ID=cds-YP_010377111.1;Parent=gene-NBT03_gp108;Dbxref=Genbank:YP_010377111.1,GeneID:72551524;Name=YP_010377111.1;Note=A4L%3B similar to Vaccinia virus strain Copenhagen A3L%3B major virion core protein p4b;gbkey=CDS;gene_name=OPG129;locus_tag=NBT03_gp108;product=MPXVgp114;protein_id=YP_010377111.1 -NC_063383.1 RefSeq gene 111057 111902 . - . ID=gene-NBT03_gp109;Dbxref=GeneID:72551525;Name=OPG130;gbkey=Gene;gene_name=OPG130;gene_biotype=protein_coding;locus_tag=NBT03_gp109;old_locus_tag=MPXV-M5312_HM12_Rivers-113 -NC_063383.1 RefSeq CDS 111057 111902 . - 0 ID=cds-YP_010377112.1;Parent=gene-NBT03_gp109;Dbxref=Genbank:YP_010377112.1,GeneID:72551525;Name=YP_010377112.1;Note=A5L%3B similar to Vaccinia virus strain Copenhagen A4L%3B 39 kDa immunodominant virion core protein needed for the progression of IV to infectious IMV;gbkey=CDS;gene_name=OPG130;locus_tag=NBT03_gp109;product=MPXVgp115;protein_id=YP_010377112.1 -NC_063383.1 RefSeq gene 111940 112425 . + . ID=gene-NBT03_gp110;Dbxref=GeneID:72551526;Name=OPG131;gbkey=Gene;gene_name=OPG131;gene_biotype=protein_coding;locus_tag=NBT03_gp110;old_locus_tag=MPXV-M5312_HM12_Rivers-114 -NC_063383.1 RefSeq CDS 111940 112425 . + 0 ID=cds-YP_010377113.1;Parent=gene-NBT03_gp110;Dbxref=Genbank:YP_010377113.1,GeneID:72551526;Name=YP_010377113.1;Note=A6R%3B similar to Vaccinia virus strain Copenhagen A5R%3B precursor of RNA polymerase 22 kDa and 21 kDa;gbkey=CDS;gene_name=OPG131;locus_tag=NBT03_gp110;product=MPXVgp116;protein_id=YP_010377113.1 -NC_063383.1 RefSeq gene 112422 113540 . - . ID=gene-NBT03_gp111;Dbxref=GeneID:72551527;Name=OPG132;gbkey=Gene;gene_name=OPG132;gene_biotype=protein_coding;locus_tag=NBT03_gp111;old_locus_tag=MPXV-M5312_HM12_Rivers-115 -NC_063383.1 RefSeq CDS 112422 113540 . - 0 ID=cds-YP_010377114.1;Parent=gene-NBT03_gp111;Dbxref=Genbank:YP_010377114.1,GeneID:72551527;Name=YP_010377114.1;Note=A7L%3B similar to Vaccinia virus strain Copenhagen A6L;gbkey=CDS;gene_name=OPG132;locus_tag=NBT03_gp111;product=MPXVgp117;protein_id=YP_010377114.1 -NC_063383.1 RefSeq gene 113564 115696 . - . ID=gene-NBT03_gp112;Dbxref=GeneID:72551528;Name=OPG133;gbkey=Gene;gene_name=OPG133;gene_biotype=protein_coding;locus_tag=NBT03_gp112;old_locus_tag=MPXV-M5312_HM12_Rivers-116 -NC_063383.1 RefSeq CDS 113564 115696 . - 0 ID=cds-YP_010377115.1;Parent=gene-NBT03_gp112;Dbxref=Genbank:YP_010377115.1,GeneID:72551528;Name=YP_010377115.1;Note=A8L%3B similar to Vaccinia virus strain Copenhagen A7L%3B early transcription factor%2C VETF%2C large subunit%3B needed for morphogenesis of the virion core;gbkey=CDS;gene_name=OPG133;locus_tag=NBT03_gp112;product=MPXVgp118;protein_id=YP_010377115.1 -NC_063383.1 RefSeq gene 115750 116628 . + . ID=gene-NBT03_gp113;Dbxref=GeneID:72551529;Name=OPG134;gbkey=Gene;gene_name=OPG134;gene_biotype=protein_coding;locus_tag=NBT03_gp113;old_locus_tag=MPXV-M5312_HM12_Rivers-117 -NC_063383.1 RefSeq CDS 115750 116628 . + 0 ID=cds-YP_010377116.1;Parent=gene-NBT03_gp113;Dbxref=Genbank:YP_010377116.1,GeneID:72551529;Name=YP_010377116.1;Note=A9R%3B similar to Vaccinia virus strain Copenhagen A8R%3B intermediate transcription factor%2C VITF-3%2C 34 kDa;gbkey=CDS;gene_name=OPG134;locus_tag=NBT03_gp113;product=MPXVgp119;protein_id=YP_010377116.1 -NC_063383.1 RefSeq gene 116609 116911 . - . ID=gene-NBT03_gp114;Dbxref=GeneID:72551530;Name=OPG135;gbkey=Gene;gene_name=OPG135;gene_biotype=protein_coding;locus_tag=NBT03_gp114;old_locus_tag=MPXV-M5312_HM12_Rivers-118 -NC_063383.1 RefSeq CDS 116609 116911 . - 0 ID=cds-YP_010377117.1;Parent=gene-NBT03_gp114;Dbxref=Genbank:YP_010377117.1,GeneID:72551530;Name=YP_010377117.1;Note=A10L%3B similar to Vaccinia virus strain Copenhagen A9L;gbkey=CDS;gene_name=OPG135;locus_tag=NBT03_gp114;product=MPXVgp120;protein_id=YP_010377117.1 -NC_063383.1 RefSeq gene 116912 119587 . - . ID=gene-NBT03_gp115;Dbxref=GeneID:72551531;Name=OPG136;gbkey=Gene;gene_name=OPG136;gene_biotype=protein_coding;locus_tag=NBT03_gp115;old_locus_tag=MPXV-M5312_HM12_Rivers-119 -NC_063383.1 RefSeq CDS 116912 119587 . - 0 ID=cds-YP_010377118.1;Parent=gene-NBT03_gp115;Dbxref=Genbank:YP_010377118.1,GeneID:72551531;Name=YP_010377118.1;Note=A11L%3B similar to Vaccinia virus strain Copenhagen A10L%3B major virion core protein p4a;gbkey=CDS;gene_name=OPG136;locus_tag=NBT03_gp115;product=MPXVgp121;protein_id=YP_010377118.1 -NC_063383.1 RefSeq gene 119602 120558 . + . ID=gene-NBT03_gp116;Dbxref=GeneID:72551532;Name=OPG137;gbkey=Gene;gene_name=OPG137;gene_biotype=protein_coding;locus_tag=NBT03_gp116;old_locus_tag=MPXV-M5312_HM12_Rivers-120 -NC_063383.1 RefSeq CDS 119602 120558 . + 0 ID=cds-YP_010377119.1;Parent=gene-NBT03_gp116;Dbxref=Genbank:YP_010377119.1,GeneID:72551532;Name=YP_010377119.1;Note=A12R%3B similar to Vaccinia virus strain Copenhagen A11R;gbkey=CDS;gene_name=OPG137;locus_tag=NBT03_gp116;product=MPXVgp122;protein_id=YP_010377119.1 -NC_063383.1 RefSeq gene 120560 121132 . - . ID=gene-NBT03_gp117;Dbxref=GeneID:72551533;Name=OPG138;gbkey=Gene;gene_name=OPG138;gene_biotype=protein_coding;locus_tag=NBT03_gp117;old_locus_tag=MPXV-M5312_HM12_Rivers-121 -NC_063383.1 RefSeq CDS 120560 121132 . - 0 ID=cds-YP_010377120.1;Parent=gene-NBT03_gp117;Dbxref=Genbank:YP_010377120.1,GeneID:72551533;Name=YP_010377120.1;Note=A13L%3B similar to Vaccinia virus strain Copenhagen A12L%3B virion core protein;gbkey=CDS;gene_name=OPG138;locus_tag=NBT03_gp117;product=MPXVgp123;protein_id=YP_010377120.1 -NC_063383.1 RefSeq gene 121156 121368 . - . ID=gene-NBT03_gp118;Dbxref=GeneID:72551534;Name=OPG139;gbkey=Gene;gene_name=OPG139;gene_biotype=protein_coding;locus_tag=NBT03_gp118;old_locus_tag=MPXV-M5312_HM12_Rivers-122 -NC_063383.1 RefSeq CDS 121156 121368 . - 0 ID=cds-YP_010377121.1;Parent=gene-NBT03_gp118;Dbxref=Genbank:YP_010377121.1,GeneID:72551534;Name=YP_010377121.1;Note=A14L%3B similar to Vaccinia virus strain Copenhagen A13L%3B IMV inner and outer membrane protein;gbkey=CDS;gene_name=OPG139;locus_tag=NBT03_gp118;product=MPXVgp124;protein_id=YP_010377121.1 -NC_063383.1 RefSeq gene 121474 121746 . - . ID=gene-NBT03_gp119;Dbxref=GeneID:72551535;Name=OPG140;gbkey=Gene;gene_name=OPG140;gene_biotype=protein_coding;locus_tag=NBT03_gp119;old_locus_tag=MPXV-M5312_HM12_Rivers-123 -NC_063383.1 RefSeq CDS 121474 121746 . - 0 ID=cds-YP_010377122.1;Parent=gene-NBT03_gp119;Dbxref=Genbank:YP_010377122.1,GeneID:72551535;Name=YP_010377122.1;Note=A15L%3B similar to Vaccinia virus strain Copenhagen A14L%3B IMV inner membrane protein;gbkey=CDS;gene_name=OPG140;locus_tag=NBT03_gp119;product=MPXVgp125;protein_id=YP_010377122.1 -NC_063383.1 RefSeq gene 121763 121924 . - . ID=gene-NBT03_gp120;Dbxref=GeneID:72551536;Name=OPG141;gbkey=Gene;gene_name=OPG141;gene_biotype=protein_coding;locus_tag=NBT03_gp120;old_locus_tag=MPXV-M5312_HM12_Rivers-124 -NC_063383.1 RefSeq CDS 121763 121924 . - 0 ID=cds-YP_010377123.1;Parent=gene-NBT03_gp120;Dbxref=Genbank:YP_010377123.1,GeneID:72551536;Name=YP_010377123.1;gbkey=CDS;gene_name=OPG141;locus_tag=NBT03_gp120;product=A15.5L;protein_id=YP_010377123.1 -NC_063383.1 RefSeq gene 121914 122198 . - . ID=gene-NBT03_gp121;Dbxref=GeneID:72551537;Name=OPG142;gbkey=Gene;gene_name=OPG142;gene_biotype=protein_coding;locus_tag=NBT03_gp121;old_locus_tag=MPXV-M5312_HM12_Rivers-125 -NC_063383.1 RefSeq CDS 121914 122198 . - 0 ID=cds-YP_010377124.1;Parent=gene-NBT03_gp121;Dbxref=Genbank:YP_010377124.1,GeneID:72551537;Name=YP_010377124.1;Note=A16L%3B similar to Vaccinia virus strain Copenhagen A15L;gbkey=CDS;gene_name=OPG142;locus_tag=NBT03_gp121;product=MPXVgp126;protein_id=YP_010377124.1 -NC_063383.1 RefSeq gene 122182 123315 . - . ID=gene-NBT03_gp122;Dbxref=GeneID:72551538;Name=OPG143;gbkey=Gene;gene_name=OPG143;gene_biotype=protein_coding;locus_tag=NBT03_gp122;old_locus_tag=MPXV-M5312_HM12_Rivers-126 -NC_063383.1 RefSeq CDS 122182 123315 . - 0 ID=cds-YP_010377125.1;Parent=gene-NBT03_gp122;Dbxref=Genbank:YP_010377125.1,GeneID:72551538;Name=YP_010377125.1;Note=A17L%3B similar to Vaccinia virus strain Copenhagen A16L%3B soluble myristylated protein;gbkey=CDS;gene_name=OPG143;locus_tag=NBT03_gp122;product=MPXVgp127;protein_id=YP_010377125.1 -NC_063383.1 RefSeq gene 123318 123932 . - . ID=gene-NBT03_gp123;Dbxref=GeneID:72551539;Name=OPG144;gbkey=Gene;gene_name=OPG144;gene_biotype=protein_coding;locus_tag=NBT03_gp123;old_locus_tag=MPXV-M5312_HM12_Rivers-127 -NC_063383.1 RefSeq CDS 123318 123932 . - 0 ID=cds-YP_010377126.1;Parent=gene-NBT03_gp123;Dbxref=Genbank:YP_010377126.1,GeneID:72551539;Name=YP_010377126.1;Note=A18L%3B similar to Vaccinia virus strain Copenhagen A17L%3B IMV surface membrane protein%3B early function in virion morphgenesis;gbkey=CDS;gene_name=OPG144;locus_tag=NBT03_gp123;product=MPXVgp128;protein_id=YP_010377126.1 -NC_063383.1 RefSeq gene 123947 125425 . + . ID=gene-NBT03_gp124;Dbxref=GeneID:72551540;Name=OPG145;gbkey=Gene;gene_name=OPG145;gene_biotype=protein_coding;locus_tag=NBT03_gp124;old_locus_tag=MPXV-M5312_HM12_Rivers-128 -NC_063383.1 RefSeq CDS 123947 125425 . + 0 ID=cds-YP_010377127.1;Parent=gene-NBT03_gp124;Dbxref=Genbank:YP_010377127.1,GeneID:72551540;Name=YP_010377127.1;Note=A19R%3B similar to Vaccinia virus strain Copenhagen A1 8R%3B virion core associated DNA helicase%3B post-replicative negative transcription elongation factor;gbkey=CDS;gene_name=OPG145;locus_tag=NBT03_gp124;product=MPXVgp129;protein_id=YP_010377127.1 -NC_063383.1 RefSeq gene 125406 125639 . - . ID=gene-NBT03_gp125;Dbxref=GeneID:72551541;Name=OPG146;gbkey=Gene;gene_name=OPG146;gene_biotype=protein_coding;locus_tag=NBT03_gp125;old_locus_tag=MPXV-M5312_HM12_Rivers-129 -NC_063383.1 RefSeq CDS 125406 125639 . - 0 ID=cds-YP_010377128.1;Parent=gene-NBT03_gp125;Dbxref=Genbank:YP_010377128.1,GeneID:72551541;Name=YP_010377128.1;Note=A20L%3B similar to Vaccinia virus strain Copenhagen A19L;gbkey=CDS;gene_name=OPG146;locus_tag=NBT03_gp125;product=MPXVgp130;protein_id=YP_010377128.1 -NC_063383.1 RefSeq gene 125640 125987 . - . ID=gene-NBT03_gp126;Dbxref=GeneID:72551542;Name=OPG147;gbkey=Gene;gene_name=OPG147;gene_biotype=protein_coding;locus_tag=NBT03_gp126;old_locus_tag=MPXV-M5312_HM12_Rivers-130 -NC_063383.1 RefSeq CDS 125640 125987 . - 0 ID=cds-YP_010377129.1;Parent=gene-NBT03_gp126;Dbxref=Genbank:YP_010377129.1,GeneID:72551542;Name=YP_010377129.1;Note=A21L%3B similar to Vaccinia virus strain Copenhagen A21L;gbkey=CDS;gene_name=OPG147;locus_tag=NBT03_gp126;product=MPXVgp131;protein_id=YP_010377129.1 -NC_063383.1 RefSeq gene 125986 127266 . + . ID=gene-NBT03_gp127;Dbxref=GeneID:72551543;Name=OPG148;gbkey=Gene;gene_name=OPG148;gene_biotype=protein_coding;locus_tag=NBT03_gp127;old_locus_tag=MPXV-M5312_HM12_Rivers-131 -NC_063383.1 RefSeq CDS 125986 127266 . + 0 ID=cds-YP_010377130.1;Parent=gene-NBT03_gp127;Dbxref=Genbank:YP_010377130.1,GeneID:72551543;Name=YP_010377130.1;Note=A22R%3B similar to Vaccinia virus strain Copenhagen A20R%3B processivity factor for the viral DNA polymerase%2C VPF;gbkey=CDS;gene_name=OPG148;locus_tag=NBT03_gp127;product=MPXVgp132;protein_id=YP_010377130.1 -NC_063383.1 RefSeq gene 127196 127759 . + . ID=gene-NBT03_gp128;Dbxref=GeneID:72551544;Name=OPG149;gbkey=Gene;gene_name=OPG149;gene_biotype=protein_coding;locus_tag=NBT03_gp128;old_locus_tag=MPXV-M5312_HM12_Rivers-132 -NC_063383.1 RefSeq CDS 127196 127759 . + 0 ID=cds-YP_010377131.1;Parent=gene-NBT03_gp128;Dbxref=Genbank:YP_010377131.1,GeneID:72551544;Name=YP_010377131.1;Note=A23R%3B similar to Vaccinia virus strain Copenhagen A22R;gbkey=CDS;gene_name=OPG149;locus_tag=NBT03_gp128;product=MPXVgp133;protein_id=YP_010377131.1 -NC_063383.1 RefSeq gene 127779 128927 . + . ID=gene-NBT03_gp129;Dbxref=GeneID:72551545;Name=OPG150;gbkey=Gene;gene_name=OPG150;gene_biotype=protein_coding;locus_tag=NBT03_gp129;old_locus_tag=MPXV-M5312_HM12_Rivers-133 -NC_063383.1 RefSeq CDS 127779 128927 . + 0 ID=cds-YP_010377132.1;Parent=gene-NBT03_gp129;Dbxref=Genbank:YP_010377132.1,GeneID:72551545;Name=YP_010377132.1;Note=A24R%3B similar to Vaccinia virus strain Copenhagen A23R%3B intermediate transcription factor%2C VITF-3%2C 45 kDa;gbkey=CDS;gene_name=OPG150;locus_tag=NBT03_gp129;product=MPXVgp134;protein_id=YP_010377132.1 -NC_063383.1 RefSeq gene 128924 132418 . + . ID=gene-NBT03_gp130;Dbxref=GeneID:72551546;Name=OPG151;gbkey=Gene;gene_name=OPG151;gene_biotype=protein_coding;locus_tag=NBT03_gp130;old_locus_tag=MPXV-M5312_HM12_Rivers-134 -NC_063383.1 RefSeq CDS 128924 132418 . + 0 ID=cds-YP_010377133.1;Parent=gene-NBT03_gp130;Dbxref=Genbank:YP_010377133.1,GeneID:72551546;Name=YP_010377133.1;Note=A25R%3B similar to Vaccinia virus strain Copenhagen A24R%3B RNA polymerase%2C 132 kDa subunit;gbkey=CDS;gene_name=OPG151;locus_tag=NBT03_gp130;product=MPXVgp135;protein_id=YP_010377133.1 -NC_063383.1 RefSeq gene 136138 137667 . - . ID=gene-NBT03_gp131;Dbxref=GeneID:72551547;Name=OPG153;gbkey=Gene;gene_name=OPG153;gene_biotype=protein_coding;locus_tag=NBT03_gp131;old_locus_tag=MPXV-M5312_HM12_Rivers-137 -NC_063383.1 RefSeq CDS 136138 137667 . - 0 ID=cds-YP_010377134.1;Parent=gene-NBT03_gp131;Dbxref=Genbank:YP_010377134.1,GeneID:72551547;Name=YP_010377134.1;Note=A28L%3B major component of IMV surface tubules%3B p4c;gbkey=CDS;gene_name=OPG153;locus_tag=NBT03_gp131;product=MPXVgp138;protein_id=YP_010377134.1 -NC_063383.1 RefSeq gene 137718 138050 . - . ID=gene-NBT03_gp132;Dbxref=GeneID:72551548;Name=OPG154;gbkey=Gene;gene_name=OPG154;gene_biotype=protein_coding;locus_tag=NBT03_gp132;old_locus_tag=MPXV-M5312_HM12_Rivers-138 -NC_063383.1 RefSeq CDS 137718 138050 . - 0 ID=cds-YP_010377135.1;Parent=gene-NBT03_gp132;Dbxref=Genbank:YP_010377135.1,GeneID:72551548;Name=YP_010377135.1;Note=A29L%3B similar to Vaccinia virus strain Copenhagen A27L%3B IMV surface membrane 14 kDa fusion protein%3B binding to cell surface heparan;gbkey=CDS;gene_name=OPG154;locus_tag=NBT03_gp132;product=MPXVgp139;protein_id=YP_010377135.1 -NC_063383.1 RefSeq gene 138051 138491 . - . ID=gene-NBT03_gp133;Dbxref=GeneID:72551549;Name=OPG155;gbkey=Gene;gene_name=OPG155;gene_biotype=protein_coding;locus_tag=NBT03_gp133;old_locus_tag=MPXV-M5312_HM12_Rivers-139 -NC_063383.1 RefSeq CDS 138051 138491 . - 0 ID=cds-YP_010377136.1;Parent=gene-NBT03_gp133;Dbxref=Genbank:YP_010377136.1,GeneID:72551549;Name=YP_010377136.1;Note=A30L%3B similar to Vaccinia virus strain Copenhagen A28L;gbkey=CDS;gene_name=OPG155;locus_tag=NBT03_gp133;product=MPXVgp140;protein_id=YP_010377136.1 -NC_063383.1 RefSeq gene 138492 139409 . - . ID=gene-NBT03_gp134;Dbxref=GeneID:72551550;Name=OPG156;gbkey=Gene;gene_name=OPG156;gene_biotype=protein_coding;locus_tag=NBT03_gp134;old_locus_tag=MPXV-M5312_HM12_Rivers-140 -NC_063383.1 RefSeq CDS 138492 139409 . - 0 ID=cds-YP_010377137.1;Parent=gene-NBT03_gp134;Dbxref=Genbank:YP_010377137.1,GeneID:72551550;Name=YP_010377137.1;Note=A31L%3B similar to Vaccinia virus strain Copenhagen A29L%3B RNA polymerase%2C 35 kDa subunit;gbkey=CDS;gene_name=OPG156;locus_tag=NBT03_gp134;product=MPXVgp141;protein_id=YP_010377137.1 -NC_063383.1 RefSeq gene 139372 139608 . - . ID=gene-NBT03_gp135;Dbxref=GeneID:72551551;Name=OPG157;gbkey=Gene;gene_name=OPG157;gene_biotype=protein_coding;locus_tag=NBT03_gp135;old_locus_tag=MPXV-M5312_HM12_Rivers-141 -NC_063383.1 RefSeq CDS 139372 139608 . - 0 ID=cds-YP_010377138.1;Parent=gene-NBT03_gp135;Dbxref=Genbank:YP_010377138.1,GeneID:72551551;Name=YP_010377138.1;Note=A32L%3B similar to Vaccinia virus strain Copenhagen A30L;gbkey=CDS;gene_name=OPG157;locus_tag=NBT03_gp135;product=MPXVgp142;protein_id=YP_010377138.1 -NC_063383.1 RefSeq gene 139641 139769 . - . ID=gene-NBT03_gp136;Dbxref=GeneID:72551552;Name=OPG158;gbkey=Gene;gene_name=OPG158;gene_biotype=protein_coding;locus_tag=NBT03_gp136;old_locus_tag=MPXV-M5312_HM12_Rivers-142 -NC_063383.1 RefSeq CDS 139641 139769 . - 0 ID=cds-YP_010377139.1;Parent=gene-NBT03_gp136;Dbxref=Genbank:YP_010377139.1,GeneID:72551552;Name=YP_010377139.1;gbkey=CDS;gene_name=OPG158;locus_tag=NBT03_gp136;product=A32.5L;protein_id=YP_010377139.1 -NC_063383.1 RefSeq gene 139768 140205 . + . ID=gene-NBT03_gp137;Dbxref=GeneID:72551553;Name=OPG159;gbkey=Gene;gene_name=OPG159;gene_biotype=protein_coding;locus_tag=NBT03_gp137;old_locus_tag=MPXV-M5312_HM12_Rivers-143 -NC_063383.1 RefSeq CDS 139768 140205 . + 0 ID=cds-YP_010377140.1;Parent=gene-NBT03_gp137;Dbxref=Genbank:YP_010377140.1,GeneID:72551553;Name=YP_010377140.1;Note=A33R%3B similar to Vaccinia virus strain Copenhagen A31R;gbkey=CDS;gene_name=OPG159;locus_tag=NBT03_gp137;product=MPXVgp143;protein_id=YP_010377140.1 -NC_063383.1 RefSeq gene 140172 141074 . - . ID=gene-NBT03_gp138;Dbxref=GeneID:72551554;Name=OPG160;gbkey=Gene;gene_name=OPG160;gene_biotype=protein_coding;locus_tag=NBT03_gp138;old_locus_tag=MPXV-M5312_HM12_Rivers-144 -NC_063383.1 RefSeq CDS 140172 141074 . - 0 ID=cds-YP_010377141.1;Parent=gene-NBT03_gp138;Dbxref=Genbank:YP_010377141.1,GeneID:72551554;Name=YP_010377141.1;Note=A34L%3B similar to Vaccinia virus strain Copenhagen A32L%3B DNA packaging into virion%3B NTP-binding motif A;gbkey=CDS;gene_name=OPG160;locus_tag=NBT03_gp138;product=MPXVgp144;protein_id=YP_010377141.1 -NC_063383.1 RefSeq gene 141102 141647 . + . ID=gene-NBT03_gp139;Dbxref=GeneID:72551555;Name=OPG161;gbkey=Gene;gene_name=OPG161;gene_biotype=protein_coding;locus_tag=NBT03_gp139;old_locus_tag=MPXV-M5312_HM12_Rivers-145 -NC_063383.1 RefSeq CDS 141102 141647 . + 0 ID=cds-YP_010377142.1;Parent=gene-NBT03_gp139;Dbxref=Genbank:YP_010377142.1,GeneID:72551555;Name=YP_010377142.1;Note=A35R%3B similar to Vaccinia virus strain Copenhagen A33R%3B EEV envelope glycoprotein%2C needed for formation of actin-containing microvilli and cell-to-cell spread of virion%3B interacts with VAC A36R;gbkey=CDS;gene_name=OPG161;locus_tag=NBT03_gp139;product=MPXVgp145;protein_id=YP_010377142.1 -NC_063383.1 RefSeq gene 141652 142158 . + . ID=gene-NBT03_gp140;Dbxref=GeneID:72551556;Name=OPG162;gbkey=Gene;gene_name=OPG162;gene_biotype=protein_coding;locus_tag=NBT03_gp140;old_locus_tag=MPXV-M5312_HM12_Rivers-146 -NC_063383.1 RefSeq CDS 141652 142158 . + 0 ID=cds-YP_010377143.1;Parent=gene-NBT03_gp140;Dbxref=Genbank:YP_010377143.1,GeneID:72551556;Name=YP_010377143.1;Note=A36R%3B similar to Vaccinia virus strain Copenhagen A3 4R%3B EEV envelope glycoprotein%2C lectin-like%3B required for infectivity of EEV%2C formation of actin-containing microvilli%2C and cell-to-cell spread of virion;gbkey=CDS;gene_name=OPG162;locus_tag=NBT03_gp140;product=MPXVgp146;protein_id=YP_010377143.1 -NC_063383.1 RefSeq gene 142202 142732 . + . ID=gene-NBT03_gp141;Dbxref=GeneID:72551557;Name=OPG163;gbkey=Gene;gene_name=OPG163;gene_biotype=protein_coding;locus_tag=NBT03_gp141;old_locus_tag=MPXV-M5312_HM12_Rivers-147 -NC_063383.1 RefSeq CDS 142202 142732 . + 0 ID=cds-YP_010377144.1;Parent=gene-NBT03_gp141;Dbxref=Genbank:YP_010377144.1,GeneID:72551557;Name=YP_010377144.1;Note=A37R%3B similar to Vaccinia virus strain Copenhagen A35R;gbkey=CDS;gene_name=OPG163;locus_tag=NBT03_gp141;product=MPXVgp147;protein_id=YP_010377144.1 -NC_063383.1 RefSeq gene 142778 143464 . + . ID=gene-NBT03_gp142;Dbxref=GeneID:72551558;Name=OPG164;gbkey=Gene;gene_name=OPG164;gene_biotype=protein_coding;locus_tag=NBT03_gp142;old_locus_tag=MPXV-M5312_HM12_Rivers-148 -NC_063383.1 RefSeq CDS 142778 143464 . + 0 ID=cds-YP_010377145.1;Parent=gene-NBT03_gp142;Dbxref=Genbank:YP_010377145.1,GeneID:72551558;Name=YP_010377145.1;Note=A38R%3B similar to Vaccinia virus strain Copenhagen A36R%3B IEV but not CEV envelope protein%3B plays critical role for actin tail formation%3B interacts with VAC A33R and A34R;gbkey=CDS;gene_name=OPG164;locus_tag=NBT03_gp142;product=MPXVgp148;protein_id=YP_010377145.1 -NC_063383.1 RefSeq gene 143516 144322 . + . ID=gene-NBT03_gp143;Dbxref=GeneID:72551559;Name=OPG165;gbkey=Gene;gene_name=OPG165;gene_biotype=protein_coding;locus_tag=NBT03_gp143;old_locus_tag=MPXV-M5312_HM12_Rivers-149 -NC_063383.1 RefSeq CDS 143516 144322 . + 0 ID=cds-YP_010377146.1;Parent=gene-NBT03_gp143;Dbxref=Genbank:YP_010377146.1,GeneID:72551559;Name=YP_010377146.1;Note=A39R%3B similar to Vaccinia virus strain Copenhagen A37R;gbkey=CDS;gene_name=OPG165;locus_tag=NBT03_gp143;product=MPXVgp149;protein_id=YP_010377146.1 -NC_063383.1 RefSeq gene 144574 145407 . - . ID=gene-NBT03_gp144;Dbxref=GeneID:72551560;Name=OPG167;gbkey=Gene;gene_name=OPG167;gene_biotype=protein_coding;locus_tag=NBT03_gp144;old_locus_tag=MPXV-M5312_HM12_Rivers-150 -NC_063383.1 RefSeq CDS 144574 145407 . - 0 ID=cds-YP_010377147.1;Parent=gene-NBT03_gp144;Dbxref=Genbank:YP_010377147.1,GeneID:72551560;Name=YP_010377147.1;Note=A40L%3B similar to Vaccinia virus strain Copenhagen A38L%3B integral membrane glycoprotein%3B immunoglobulin-like%3B regulation of the influx of extracellular Ca2+;gbkey=CDS;gene_name=OPG167;locus_tag=NBT03_gp144;product=MPXVgp150;protein_id=YP_010377147.1 -NC_063383.1 RefSeq gene 146113 146778 . - . ID=gene-NBT03_gp145;Dbxref=GeneID:72551561;Name=OPG170;gbkey=Gene;gene_name=OPG170;gene_biotype=protein_coding;locus_tag=NBT03_gp145;old_locus_tag=MPXV-M5312_HM12_Rivers-151 -NC_063383.1 RefSeq CDS 146113 146778 . - 0 ID=cds-YP_010377148.1;Parent=gene-NBT03_gp145;Dbxref=Genbank:YP_010377148.1,GeneID:72551561;Name=YP_010377148.1;Note=A41L%3B similar to Vaccinia virus strain Copenhagen A41L%3B secreted protein reducing infiltration of inflammatory cells into the infected area;gbkey=CDS;gene_name=OPG170;locus_tag=NBT03_gp145;product=MPXVgp151;protein_id=YP_010377148.1 -NC_063383.1 RefSeq gene 146988 147389 . + . ID=gene-NBT03_gp146;Dbxref=GeneID:72551562;Name=OPG171;gbkey=Gene;gene_name=OPG171;gene_biotype=protein_coding;locus_tag=NBT03_gp146;old_locus_tag=MPXV-M5312_HM12_Rivers-152 -NC_063383.1 RefSeq CDS 146988 147389 . + 0 ID=cds-YP_010377149.1;Parent=gene-NBT03_gp146;Dbxref=Genbank:YP_010377149.1,GeneID:72551562;Name=YP_010377149.1;Note=A42R%3B similar to Vaccinia virus strain Copenhagen A42R%3B profilin-like;gbkey=CDS;gene_name=OPG171;locus_tag=NBT03_gp146;product=MPXVgp152;protein_id=YP_010377149.1 -NC_063383.1 RefSeq gene 147427 148017 . + . ID=gene-NBT03_gp147;Dbxref=GeneID:72551563;Name=OPG172;gbkey=Gene;gene_name=OPG172;gene_biotype=protein_coding;locus_tag=NBT03_gp147;old_locus_tag=MPXV-M5312_HM12_Rivers-153 -NC_063383.1 RefSeq CDS 147427 148017 . + 0 ID=cds-YP_010377150.1;Parent=gene-NBT03_gp147;Dbxref=Genbank:YP_010377150.1,GeneID:72551563;Name=YP_010377150.1;Note=A43R%3B similar to Vaccinia virus strain Copenhagen A43R%3B membrane glycoprotein;gbkey=CDS;gene_name=OPG172;locus_tag=NBT03_gp147;product=MPXVgp153;protein_id=YP_010377150.1 -NC_063383.1 RefSeq gene 148037 148261 . + . ID=gene-NBT03_gp148;Dbxref=GeneID:72551564;Name=OPG173;gbkey=Gene;gene_name=OPG173;gene_biotype=protein_coding;locus_tag=NBT03_gp148;old_locus_tag=MPXV-M5312_HM12_Rivers-154 -NC_063383.1 RefSeq CDS 148037 148261 . + 0 ID=cds-YP_010377151.1;Parent=gene-NBT03_gp148;Dbxref=Genbank:YP_010377151.1,GeneID:72551564;Name=YP_010377151.1;Note=A44R;gbkey=CDS;gene_name=OPG173;locus_tag=NBT03_gp148;product=MPXVgp154;protein_id=YP_010377151.1 -NC_063383.1 RefSeq gene 148355 149395 . - . ID=gene-NBT03_gp149;Dbxref=GeneID:72551565;Name=OPG174;gbkey=Gene;gene_name=OPG174;gene_biotype=protein_coding;locus_tag=NBT03_gp149;old_locus_tag=MPXV-M5312_HM12_Rivers-155 -NC_063383.1 RefSeq CDS 148355 149395 . - 0 ID=cds-YP_010377152.1;Parent=gene-NBT03_gp149;Dbxref=Genbank:YP_010377152.1,GeneID:72551565;Name=YP_010377152.1;Note=A45L%3B similar to Vaccinia virus strain Copenhagen A44L%3B 3-b-Hydroxy-delta5-steroid dehydrogenase;gbkey=CDS;gene_name=OPG174;locus_tag=NBT03_gp149;product=MPXVgp158;protein_id=YP_010377152.1 -NC_063383.1 RefSeq gene 149442 149819 . + . ID=gene-NBT03_gp150;Dbxref=GeneID:72551566;Name=OPG175;gbkey=Gene;gene_name=OPG175;gene_biotype=protein_coding;locus_tag=NBT03_gp150;old_locus_tag=MPXV-M5312_HM12_Rivers-156 -NC_063383.1 RefSeq CDS 149442 149819 . + 0 ID=cds-YP_010377153.1;Parent=gene-NBT03_gp150;Dbxref=Genbank:YP_010377153.1,GeneID:72551566;Name=YP_010377153.1;Note=A46R%3B similar to Vaccinia virus strain Copenhagen A45R%3B superoxide dismutase-like%3B virion core protein;gbkey=CDS;gene_name=OPG175;locus_tag=NBT03_gp150;product=MPXVgp156;protein_id=YP_010377153.1 -NC_063383.1 RefSeq gene 149809 150531 . + . ID=gene-NBT03_gp151;Dbxref=GeneID:72551567;Name=OPG176;gbkey=Gene;gene_name=OPG176;gene_biotype=protein_coding;locus_tag=NBT03_gp151;old_locus_tag=MPXV-M5312_HM12_Rivers-157 -NC_063383.1 RefSeq CDS 149809 150531 . + 0 ID=cds-YP_010377154.1;Parent=gene-NBT03_gp151;Dbxref=Genbank:YP_010377154.1,GeneID:72551567;Name=YP_010377154.1;Note=A47R%3B similar to Vaccinia virus strain Copenhagen A46R;gbkey=CDS;gene_name=OPG176;locus_tag=NBT03_gp151;product=MPXVgp157;protein_id=YP_010377154.1 -NC_063383.1 RefSeq gene 151509 152123 . + . ID=gene-NBT03_gp152;Dbxref=GeneID:72551568;Name=OPG178;gbkey=Gene;gene_name=OPG178;gene_biotype=protein_coding;locus_tag=NBT03_gp152;old_locus_tag=MPXV-M5312_HM12_Rivers-158 -NC_063383.1 RefSeq CDS 151509 152123 . + 0 ID=cds-YP_010377155.1;Parent=gene-NBT03_gp152;Dbxref=Genbank:YP_010377155.1,GeneID:72551568;Name=YP_010377155.1;Note=A49R%3B similar to Vaccinia virus strain Copenhagen A48R%3B thymidylate kinase;gbkey=CDS;gene_name=OPG178;locus_tag=NBT03_gp152;product=MPXVgp159;protein_id=YP_010377155.1 -NC_063383.1 RefSeq gene 152692 154371 . + . ID=gene-NBT03_gp153;Dbxref=GeneID:72551569;Name=OPG180;gbkey=Gene;gene_name=OPG180;gene_biotype=protein_coding;locus_tag=NBT03_gp153;old_locus_tag=MPXV-M5312_HM12_Rivers-159 -NC_063383.1 RefSeq CDS 152692 154371 . + 0 ID=cds-YP_010377156.1;Parent=gene-NBT03_gp153;Dbxref=Genbank:YP_010377156.1,GeneID:72551569;Name=YP_010377156.1;Note=A50R%3B similar to Vaccinia virus strain Copenhagen A50R%3B DNA ligase;gbkey=CDS;gene_name=OPG180;locus_tag=NBT03_gp153;product=MPXVgp160;protein_id=YP_010377156.1 -NC_063383.1 RefSeq gene 154412 155416 . + . ID=gene-NBT03_gp154;Dbxref=GeneID:72551570;Name=OPG181;gbkey=Gene;gene_name=OPG181;gene_biotype=protein_coding;locus_tag=NBT03_gp154;old_locus_tag=MPXV-M5312_HM12_Rivers-160 -NC_063383.1 RefSeq CDS 154412 155416 . + 0 ID=cds-YP_010377157.1;Parent=gene-NBT03_gp154;Dbxref=Genbank:YP_010377157.1,GeneID:72551570;Name=YP_010377157.1;Note=A51R%3B similar to Vaccinia virus strain Copenhagen A51R;gbkey=CDS;gene_name=OPG181;locus_tag=NBT03_gp154;product=MPXVgp161;protein_id=YP_010377157.1 -NC_063383.1 RefSeq gene 158917 159858 . + . ID=gene-NBT03_gp155;Dbxref=GeneID:72551571;Name=OPG185;gbkey=Gene;gene_name=OPG185;gene_biotype=protein_coding;locus_tag=NBT03_gp155;old_locus_tag=MPXV-M5312_HM12_Rivers-162 -NC_063383.1 RefSeq CDS 158917 159858 . + 0 ID=cds-YP_010377158.1;Parent=gene-NBT03_gp155;Dbxref=Genbank:YP_010377158.1,GeneID:72551571;Name=YP_010377158.1;Note=B2R%3B similar to Vaccinia virus strain Copenhagen A56R%3B EEV envelope and cell membrane glycoprotein hemagglutinin%3B inhibition of the ability of infected cells to fuse%3B interacts with VAC F13L;gbkey=CDS;gene_name=OPG185;locus_tag=NBT03_gp155;product=MPXVgp163;protein_id=YP_010377158.1 -NC_063383.1 RefSeq gene 160622 161533 . + . ID=gene-NBT03_gp156;Dbxref=GeneID:72551572;Name=OPG187;gbkey=Gene;gene_name=OPG187;gene_biotype=protein_coding;locus_tag=NBT03_gp156;old_locus_tag=MPXV-M5312_HM12_Rivers-163 -NC_063383.1 RefSeq CDS 160622 161533 . + 0 ID=cds-YP_010377159.1;Parent=gene-NBT03_gp156;Dbxref=Genbank:YP_010377159.1,GeneID:72551572;Name=YP_010377159.1;Note=B3R%3B similar to Vaccinia virus strain Copenhagen B1R%3B serine;gbkey=CDS;gene_name=OPG187;locus_tag=NBT03_gp156;product=MPXVgp164;protein_id=YP_010377159.1 -NC_063383.1 RefSeq gene 161596 163107 . + . ID=gene-NBT03_gp157;Dbxref=GeneID:72551573;Name=OPG188;gbkey=Gene;gene_name=OPG188;gene_biotype=protein_coding;locus_tag=NBT03_gp157;old_locus_tag=MPXV-M5312_HM12_Rivers-164 -NC_063383.1 RefSeq CDS 161596 163107 . + 0 ID=cds-YP_010377160.1;Parent=gene-NBT03_gp157;Dbxref=Genbank:YP_010377160.1,GeneID:72551573;Name=YP_010377160.1;Note=B4R%3B schlafen-like;gbkey=CDS;gene_name=OPG188;locus_tag=NBT03_gp157;product=MPXVgp165;protein_id=YP_010377160.1 -NC_063383.1 RefSeq gene 163333 165018 . + . ID=gene-NBT03_gp158;Dbxref=GeneID:72551574;Name=OPG189;gbkey=Gene;gene_name=OPG189;gene_biotype=protein_coding;locus_tag=NBT03_gp158;old_locus_tag=MPXV-M5312_HM12_Rivers-165 -NC_063383.1 RefSeq CDS 163333 165018 . + 0 ID=cds-YP_010377161.1;Parent=gene-NBT03_gp158;Dbxref=Genbank:YP_010377161.1,GeneID:72551574;Name=YP_010377161.1;Note=B5R%3B similar to Vaccinia virus strain Copenhagen B4R%3B ankyrin-like;gbkey=CDS;gene_name=OPG189;locus_tag=NBT03_gp158;product=MPXVgp166;protein_id=YP_010377161.1 -NC_063383.1 RefSeq gene 165122 166075 . + . ID=gene-NBT03_gp159;Dbxref=GeneID:72551575;Name=OPG190;gbkey=Gene;gene_name=OPG190;gene_biotype=protein_coding;locus_tag=NBT03_gp159;old_locus_tag=MPXV-M5312_HM12_Rivers-166 -NC_063383.1 RefSeq CDS 165122 166075 . + 0 ID=cds-YP_010377162.1;Parent=gene-NBT03_gp159;Dbxref=Genbank:YP_010377162.1,GeneID:72551575;Name=YP_010377162.1;Note=B6R%3B similar to Vaccinia virus strain Copenhagen B5R%3B palmitated 42 kDa glycoprotein located both on the membranes of infected cells and on EEV envelope%3B complement control protein-like;gbkey=CDS;gene_name=OPG190;locus_tag=NBT03_gp159;product=MPXVgp167;protein_id=YP_010377162.1 -NC_063383.1 RefSeq gene 166161 166667 . + . ID=gene-NBT03_gp160;Dbxref=GeneID:72551576;Name=OPG191;gbkey=Gene;gene_name=OPG191;gene_biotype=protein_coding;locus_tag=NBT03_gp160;old_locus_tag=MPXV-M5312_HM12_Rivers-167 -NC_063383.1 RefSeq CDS 166161 166667 . + 0 ID=cds-YP_010377163.1;Parent=gene-NBT03_gp160;Dbxref=Genbank:YP_010377163.1,GeneID:72551576;Name=YP_010377163.1;Note=B7R%3B similar to Vaccinia virus strain Copenhagen B6R;gbkey=CDS;gene_name=OPG191;locus_tag=NBT03_gp160;product=MPXVgp168;protein_id=YP_010377163.1 -NC_063383.1 RefSeq gene 166731 167279 . + . ID=gene-NBT03_gp161;Dbxref=GeneID:72551577;Name=OPG192;gbkey=Gene;gene_name=OPG192;gene_biotype=protein_coding;locus_tag=NBT03_gp161;old_locus_tag=MPXV-M5312_HM12_Rivers-168 -NC_063383.1 RefSeq CDS 166731 167279 . + 0 ID=cds-YP_010377164.1;Parent=gene-NBT03_gp161;Dbxref=Genbank:YP_010377164.1,GeneID:72551577;Name=YP_010377164.1;Note=B8R%3B similar to Vaccinia virus strain Copenhagen B7R;gbkey=CDS;gene_name=OPG192;locus_tag=NBT03_gp161;product=MPXVgp169;protein_id=YP_010377164.1 -NC_063383.1 RefSeq gene 167334 168137 . + . ID=gene-NBT03_gp162;Dbxref=GeneID:72551578;Name=OPG193;gbkey=Gene;gene_name=OPG193;gene_biotype=protein_coding;locus_tag=NBT03_gp162;old_locus_tag=MPXV-M5312_HM12_Rivers-169 -NC_063383.1 RefSeq CDS 167334 168137 . + 0 ID=cds-YP_010377165.1;Parent=gene-NBT03_gp162;Dbxref=Genbank:YP_010377165.1,GeneID:72551578;Name=YP_010377165.1;Note=B9R%3B similar to Vaccinia virus strain Copenhagen B8R%3B secreted IFN-g binding protein;gbkey=CDS;gene_name=OPG193;locus_tag=NBT03_gp162;product=MPXVgp170;protein_id=YP_010377165.1 -NC_063383.1 RefSeq gene 168230 168895 . + . ID=gene-NBT03_gp163;Dbxref=GeneID:72551579;Name=OPG195;gbkey=Gene;gene_name=OPG195;gene_biotype=protein_coding;locus_tag=NBT03_gp163;old_locus_tag=MPXV-M5312_HM12_Rivers-170 -NC_063383.1 RefSeq CDS 168230 168895 . + 0 ID=cds-YP_010377166.1;Parent=gene-NBT03_gp163;Dbxref=Genbank:YP_010377166.1,GeneID:72551579;Name=YP_010377166.1;Note=B10R%3B shope fibroma virus T4 protein-like;gbkey=CDS;gene_name=OPG195;locus_tag=NBT03_gp163;product=MPXVgp171;protein_id=YP_010377166.1 -NC_063383.1 RefSeq gene 169670 169972 . + . ID=gene-NBT03_gp164;Dbxref=GeneID:72551580;Name=OPG197;gbkey=Gene;gene_name=OPG197;gene_biotype=protein_coding;locus_tag=NBT03_gp164;old_locus_tag=MPXV-M5312_HM12_Rivers-171 -NC_063383.1 RefSeq CDS 169670 169972 . + 0 ID=cds-YP_010377167.1;Parent=gene-NBT03_gp164;Dbxref=Genbank:YP_010377167.1,GeneID:72551580;Name=YP_010377167.1;gbkey=CDS;gene_name=OPG197;locus_tag=NBT03_gp164;product=Hypothetical protein (Cop-B11R);protein_id=YP_010377167.1 -NC_063383.1 RefSeq gene 170038 170886 . + . ID=gene-NBT03_gp165;Dbxref=GeneID:72551581;Name=OPG198;gbkey=Gene;gene_name=OPG198;gene_biotype=protein_coding;locus_tag=NBT03_gp165;old_locus_tag=MPXV-M5312_HM12_Rivers-172 -NC_063383.1 RefSeq CDS 170038 170886 . + 0 ID=cds-YP_010377168.1;Parent=gene-NBT03_gp165;Dbxref=Genbank:YP_010377168.1,GeneID:72551581;Name=YP_010377168.1;Note=B11R%3B similar to Vaccinia virus strain Copenhagen B12R%3B protein kinase-like;gbkey=CDS;gene_name=OPG198;locus_tag=NBT03_gp165;product=MPXVgp172;protein_id=YP_010377168.1 -NC_063383.1 RefSeq gene 170988 172022 . + . ID=gene-NBT03_gp166;Dbxref=GeneID:72551582;Name=OPG199;gbkey=Gene;gene_name=OPG199;gene_biotype=protein_coding;locus_tag=NBT03_gp166;old_locus_tag=MPXV-M5312_HM12_Rivers-173 -NC_063383.1 RefSeq CDS 170988 172022 . + 0 ID=cds-YP_010377169.1;Parent=gene-NBT03_gp166;Dbxref=Genbank:YP_010377169.1,GeneID:72551582;Name=YP_010377169.1;Note=SPI-2%3B B12R%3B serine protease inhibitor-like%2C SPI-2%3B inhibition of the IL-1b converting enzyme%3B apoptosis inhibition;gbkey=CDS;gene_name=OPG199;locus_tag=NBT03_gp166;product=MPXVgp173;protein_id=YP_010377169.1 -NC_063383.1 RefSeq gene 172150 172599 . + . ID=gene-NBT03_gp167;Dbxref=GeneID:72551583;Name=OPG200;gbkey=Gene;gene_name=OPG200;gene_biotype=protein_coding;locus_tag=NBT03_gp167;old_locus_tag=MPXV-M5312_HM12_Rivers-174 -NC_063383.1 RefSeq CDS 172150 172599 . + 0 ID=cds-YP_010377170.1;Parent=gene-NBT03_gp167;Dbxref=Genbank:YP_010377170.1,GeneID:72551583;Name=YP_010377170.1;Note=B13R%3B similar to Vaccinia virus strain Copenhagen B15R;gbkey=CDS;gene_name=OPG200;locus_tag=NBT03_gp167;product=MPXVgp174;protein_id=YP_010377170.1 -NC_063383.1 RefSeq gene 174532 175587 . + . ID=gene-NBT03_gp168;Dbxref=GeneID:72551584;Name=OPG204;gbkey=Gene;gene_name=OPG204;gene_biotype=protein_coding;locus_tag=NBT03_gp168;old_locus_tag=MPXV-M5312_HM12_Rivers-177 -NC_063383.1 RefSeq CDS 174532 175587 . + 0 ID=cds-YP_010377172.1;Parent=gene-NBT03_gp168;Dbxref=Genbank:YP_010377172.1,GeneID:72551584;Name=YP_010377172.1;Note=B16R%3B similar to Vaccinia virus strain Copenhagen B19R%3B cell surface antigen and secreted IFN-a;gbkey=CDS;gene_name=OPG204;locus_tag=NBT03_gp168;product=MPXVgp177;protein_id=YP_010377172.1 -NC_063383.1 RefSeq gene 175656 178019 . + . ID=gene-NBT03_gp169;Dbxref=GeneID:72551585;Name=OPG205;gbkey=Gene;gene_name=OPG205;gene_biotype=protein_coding;locus_tag=NBT03_gp169;old_locus_tag=MPXV-M5312_HM12_Rivers-178 -NC_063383.1 RefSeq CDS 175656 178019 . + 0 ID=cds-YP_010377173.1;Parent=gene-NBT03_gp169;Dbxref=Genbank:YP_010377173.1,GeneID:72551585;Name=YP_010377173.1;Note=B17R%3B ankyrin-like;gbkey=CDS;gene_name=OPG205;locus_tag=NBT03_gp169;product=MPXVgp178;protein_id=YP_010377173.1 -NC_063383.1 RefSeq gene 179266 180339 . + . ID=gene-NBT03_gp170;Dbxref=GeneID:72551586;Name=OPG208;gbkey=Gene;gene_name=OPG208;gene_biotype=protein_coding;locus_tag=NBT03_gp170;old_locus_tag=MPXV-M5312_HM12_Rivers-180 -NC_063383.1 RefSeq CDS 179266 180339 . + 0 ID=cds-YP_010377174.1;Parent=gene-NBT03_gp170;Dbxref=Genbank:YP_010377174.1,GeneID:72551586;Name=YP_010377174.1;Note=SPI-1%3B B19R%3B serine protease inhibitor-like%2C SPI-1%3B apoptosis inhibition;gbkey=CDS;gene_name=OPG208;locus_tag=NBT03_gp170;product=MPXVgp180;protein_id=YP_010377174.1 -NC_063383.1 RefSeq gene 180518 181090 . + . ID=gene-NBT03_gp171;Dbxref=GeneID:72551587;Name=OPG209;gbkey=Gene;gene_name=OPG209;gene_biotype=protein_coding;locus_tag=NBT03_gp171;old_locus_tag=MPXV-M5312_HM12_Rivers-181 -NC_063383.1 RefSeq CDS 180518 181090 . + 0 ID=cds-YP_010377175.1;Parent=gene-NBT03_gp171;Dbxref=Genbank:YP_010377175.1,GeneID:72551587;Name=YP_010377175.1;Note=B20R;gbkey=CDS;gene_name=OPG209;locus_tag=NBT03_gp171;product=MPXVgp181;protein_id=YP_010377175.1 -NC_063383.1 RefSeq gene 181356 186998 . + . ID=gene-NBT03_gp172;Dbxref=GeneID:72551588;Name=OPG210;gbkey=Gene;gene_name=OPG210;gene_biotype=protein_coding;locus_tag=NBT03_gp172;old_locus_tag=MPXV-M5312_HM12_Rivers-182 -NC_063383.1 RefSeq CDS 181356 186998 . + 0 ID=cds-YP_010377176.1;Parent=gene-NBT03_gp172;Dbxref=Genbank:YP_010377176.1,GeneID:72551588;Name=YP_010377176.1;Note=B21R%3B putative membrane-associated glycoprotein%3B cadherin-like domain;gbkey=CDS;gene_name=OPG210;locus_tag=NBT03_gp172;product=MPXVgp182;protein_id=YP_010377176.1 -NC_063383.1 RefSeq gene 189199 189660 . + . ID=gene-NBT03_gp173;Dbxref=GeneID:72551589;Name=OPG005;gbkey=Gene;gene_name=OPG005;gene_biotype=protein_coding;locus_tag=NBT03_gp173;old_locus_tag=MPXV-M5312_HM12_Rivers-184 -NC_063383.1 RefSeq CDS 189199 189660 . + 0 ID=cds-YP_010377177.1;Parent=gene-NBT03_gp173;Dbxref=Genbank:YP_010377177.1,GeneID:72551589;Name=YP_010377177.1;Note=N1R%3B similar to Vaccinia virus strain Copenhagen B22R%3B VAC B15R-like;gbkey=CDS;gene_name=OPG005;locus_tag=NBT03_gp173;product=MPXVgp185;protein_id=YP_010377177.1 -NC_063383.1 RefSeq gene 190410 190940 . + . ID=gene-NBT03_gp174;Dbxref=GeneID:72551590;Name=NBT03_gp174;gbkey=Gene;gene_biotype=protein_coding;locus_tag=NBT03_gp174;old_locus_tag=MPXV-M5312_HM12_Rivers-186 -NC_063383.1 RefSeq CDS 190410 190940 . + 0 ID=cds-YP_010377184.1;Parent=gene-NBT03_gp174;Dbxref=Genbank:YP_010377184.1,GeneID:72551590;Name=YP_010377184.1;gbkey=CDS;locus_tag=NBT03_gp174;product=hypothetical protein;protein_id=YP_010377184.1 -NC_063383.1 RefSeq gene 191054 192367 . + . ID=gene-NBT03_gp175;Dbxref=GeneID:72551591;Name=NBT03_gp175;gbkey=Gene;gene_biotype=protein_coding;locus_tag=NBT03_gp175;old_locus_tag=MPXV-M5312_HM12_Rivers-187 -NC_063383.1 RefSeq CDS 191054 192367 . + 0 ID=cds-YP_010377179.1;Parent=gene-NBT03_gp175;Dbxref=Genbank:YP_010377179.1,GeneID:72551591;Name=YP_010377179.1;Note=N4R%3B ankyrin-like;gbkey=CDS;locus_tag=NBT03_gp175;product=MPXVgp188;protein_id=YP_010377179.1 -NC_063383.1 RefSeq gene 192603 194369 . + . ID=gene-NBT03_gp176;Dbxref=GeneID:72551592;Name=OPG003;gbkey=Gene;gene_name=OPG003;gene_biotype=protein_coding;locus_tag=NBT03_gp176;old_locus_tag=MPXV-M5312_HM12_Rivers-188 -NC_063383.1 RefSeq CDS 192603 194369 . + 0 ID=cds-YP_010377180.1;Parent=gene-NBT03_gp176;Dbxref=Genbank:YP_010377180.1,GeneID:72551592;Name=YP_010377180.1;Note=J1R%3B ankyrin-like;gbkey=CDS;gene_name=OPG003;locus_tag=NBT03_gp176;product=MPXVgp189;protein_id=YP_010377180.1 -NC_063383.1 RefSeq gene 194459 195508 . + . ID=gene-NBT03_gp177;Dbxref=GeneID:72551593;Name=OPG002;gbkey=Gene;gene_name=OPG002;gene_biotype=protein_coding;locus_tag=NBT03_gp177;old_locus_tag=MPXV-M5312_HM12_Rivers-189 -NC_063383.1 RefSeq CDS 194459 195508 . + 0 ID=cds-YP_010377181.1;Parent=gene-NBT03_gp177;Dbxref=Genbank:YP_010377181.1,GeneID:72551593;Name=YP_010377181.1;Note=J2R%3B secreted TNF binding protein;gbkey=CDS;gene_name=OPG002;locus_tag=NBT03_gp177;product=MPXVgp190;protein_id=YP_010377181.1 -NC_063383.1 RefSeq gene 195635 196375 . + . ID=gene-NBT03_gp178;Dbxref=GeneID:72551594;Name=OPG001;gbkey=Gene;gene_name=OPG001;gene_biotype=protein_coding;locus_tag=NBT03_gp178;old_locus_tag=MPXV-M5312_HM12_Rivers-190 -NC_063383.1 RefSeq CDS 195635 196375 . + 0 ID=cds-YP_010377182.1;Parent=gene-NBT03_gp178;Dbxref=Genbank:YP_010377182.1,GeneID:72551594;Name=YP_010377182.1;Note=J3R%3B similar to Vaccinia virus strain Copenhagen B29R%3B CC-chemokine binding;gbkey=CDS;gene_name=OPG001;locus_tag=NBT03_gp178;product=MPXVgp191;protein_id=YP_010377182.1 diff --git a/data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/reference.fasta b/data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/reference.fasta deleted file mode 100644 index 2500fd78..00000000 --- a/data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/reference.fasta +++ /dev/null @@ -1,3288 +0,0 @@ ->MPXV_USA_2022_MA001_in_NC_063383_coordinates -attttactattttatttagtgtctagaaaaaaatgtgtgacccacgaccgtaggaaactc -tagagggtaagaaaaatcaatcgtttatagagaccatcagaaagaggtttaatatttttg -tgagacctatcgaagagagaaaggataaaaactttttacgactccatcagaaagaggttt -aatatttttgtgagacccatcgaagagagaaagagatggttagtcaagatatttttctta -gtacaaaagtcaatgttttaaaatatatggacgagaattaatttgtctgtataaaaactt -gtgtgaaattatgtactagagaaaaaacgtgagcagtgtcccctacatggattttacaga -tcatttatattccaaaaatattaactatatacgtttattatatgatgttaacgtgtaaat -tataaacattattttatgatgcaattgtctgacaacctagattggtataaggatgttgat -aagctctacgagaatatattgttggacgttatcgtttacgaaatagttgagacatcagaa -agaggtttaatatttttgtgagaccatcgaagagagaaagagaataaaaatatttttttt -tttttttttgtaaaacttttttatgagaccaagagaatacgaatagtgatcatatcgtat -cacatattgaaacagaaagaagaagtaacgagaggtaactttttgtgaatgtagttaaat -atttttgttttgcaaaccggaatatagtgcccggtcttttttaattcgtggtgcggtgtc -tgaatcgttcgattaacccaactcatccattttcagatgaatagagttatcgattcagac -acatgctttgagttttgttgaatcgatgagtgaagtatcatcggttgcaccttcagatgc -cgatccgtcgacatacttgaatccatccttgacttcaagttcagatgattcctcacacat -gtctccgatacgtacgctaaactctaggttcttgacacattttgtatcaacgatcgttga -accgatgatatctttgtaactcactttcttatgtgagatgttagacccaagtactggatg -ggtcttgatgtcactgtctttctcttcttcgctacatctgatgtcgatagacatctcaca -gtctttgatcatagccagagcttcttcacgcgtgatcgcgggagagtccttaccttgtcc -cggtgacacgctggacaatctagtattcacagtgtttccatcagaggattcggagatgga -taaaatctttgggcatttggtgaatccaaagttcatgttaagacccgcaccgacgatagt -gtaataagtggtgggatctccttttacaacttcttcggatacctcatcatcttcggtctc -tgtaacttccgttacggattgacaaatcttatcattggtcggtgtttggtcttgctttgt -gactttgataataacatcgattcccatatgatgtttgttttcttcttcagtacacgagga -tgaagattgttgaagactagtaggcatagcagctgccactaggcacatgcatgccaggac -aatatattgtttcatgattgctattgattgattactgttctagatgattctactttctta -ccatataataaattagaatatattttctacttttacgagaaattaattattgtatttatt -atttataggtaaaaaaacttactataagtgggtgggattctgggaattagtgatcagttt -atgtatatcgcaactagcgggcatatggctattgacatcgagaacattacccatatgata -agagattgtatcattttcgtagtcttgagtattggtattactatatagtatgtagatgtc -gacgctagatagacagtcgcccactagagttaccgtctctgaatgcggcatgatagtatc -attctttgttttcgttaactgtttggaagatgaatctttgttgttacatttaatctcgaa -attcagagtacatatctttgaagtattctgatatctattttctcctgtaaagaatcctga -agttgctacattattaaggacagagaagtattctgcacgaaagactggatcacaatcttt -atgattcatggtaatagttagttccgacgttgagatggattcgctgagaccggtagtggt -cgtccgagtacacgatgtgtcgttgactggatacaggttaatttccacatcgatatagtt -aaatgtattgctggttacgacgggttcgcatttatctgtggaagagacggtgtgagaata -tgttccgggaccacacggagaacagatgacgtctccggtagacgtgtatccggatactcc -gtatcctattccacactttgttttagaaatacatgttctacaccctgatgctcctttgag -aagacaataatatcctggagagcattcacagattctattgtgagtcgtgttacacgatcg -cgtctctacctgattactatcacatcttccgttacaacttagacaagcctgtaaatgatt -attgtgagatgtaaaggtatccgaaccacacggtgtacattgtgtattagtcttgctatc -acataatctgaaagcgtaagttcccggaggacacgatagacaacatagattacggcttct -gtattcgttgtctttacactttccattggatggtgcatgtggtgctatatctcttccgtt -tattattatacatgagagaaacaatatatacgagtataatacggacctcatgatttaata -atgtagtaatcgtcgtcttgttactgtttgtttcctacttctccaatcatatagattatt -ttttaaatattttctttctatcatggataatatttgtaatggttctttccgtacaacata -ctgtttagatggtagtcgcttagcttggttatgatattgcgcataatttccggaggcaaa -tacgatagtctagattgactatcgatggtagactctaatttattgagtgctttgtcgacg -agtttacttttatgctccatcgatagatgacactgttctatgagatcgtcgtacatggga -aatgaaatgcgtttgtctgaatgtatggcttcgagatatgtgtgataccgaatgtcttct -gttctcaataccgtatacaagtcggtgtctgagattcgaatctctttgaggagacttatg -tcacgactacatttttcgatgatggaatctatcttatcgaatgatatatttttcataaat -acacttttatagtcctcgtttaaacagaatttagtatgtagttccgcaaatgactcgtcc -cttaataggcagtaggctattatcttctttacgtagtgatcgtcgtagggagagaactcc -gacatcttgtagaacaacgatttaatcataggtagagatactttcagtctgtggtggata -atgtcattaacgacatccgccttgtatataatgtttctgttttcaaacaccaagtcgaat -actgtcttatcgtctttagtcggaaggttgatgtcgtatccaatgtatacgaggtatgag -gcaacattgttattgcaattctggaaggcggtatgaagaggagtcattgtattatagtat -tcgtctttctgaatgtcgaatctatctagtagataccgtagtatattgagagagcgactt -ccatatccttgattatgttttatgaatagataaagtagatgttgtccttcttccttttgt -aatttcccgtatttttgttcgtgccaattgagtaacattatgagaatatgacctgttgca -caatcgttctttatgtattccatgatgggtgtacaattaagattattacgtatcctcgta -tcggctcctcgagataaaagagcatacaccacacgaggactatgtttggtatactgttga -aggtaagtgtgtaacggcgtatttccgattttcgtaaccgcgttaatgtttgctccatga -tctattatcgcgtagatgaatcgcttctcagctcgcatcttagtgtgactctttgacttg -taataattgctttcgtggaacgcggatatgtgtttacagtagtaatgaagagaagtgagt -ccatcctcatcgacgcaattagggtcagatcctttagtcaataatttgtacagaacgtaa -tagtttaagctcccattgaatttatatctaagataacacagcaatagatcggatgattta -ctaaagtcatcaatggggtccgttagtatatcaaagatcttgttatcgattgatagtgaa -tgaatcagatagtggtgtagaggaatatgtccttttttatccttgctatcaaagttacgc -atgccgtggcgtaacaatatctttaatacagatggattaaatcgtgtattcatcgtatag -caatgtaatggagagttaccacattttagtcgtttattcagatcgcagtgtttaataact -aatttaaacagatgagatgatatatccacatcaaagaatgcgagatacatatgacagaca -ttattgacagaaatgtgaccttcattatcaccgtcgtccataaatgcgttaggtacgtac -cacatactatcgttaacgatgcgcacaatctcgtccatttcatccatcttcataatgatt -tactttttcataattagagaaaaagatcaaggtataaaaattagaagtgttagactataa -actaacttatgacttaactaacttatgacttaactaacttatgacttaactaacttatga -cttaactaacttatgacttaactaacttatgacttaactaacttatgacttaactaactt -atgactattaactcatttcaagaaaggtgggtggatagaactctatatgacagcttgtga -aacaattagatccctaatttctaatggaagttttgataggagattgtcatcagttgatac -attgtttattatctcatctattagagcacgtctgtttagagctttagtgacctgctcggt -tacttctgtgtaaatcttgaatcctttagtgatacactgtgtcaaaactggatgtttaga -atacctatgtagaatatgggaagcatgcttgtttttgtctctattatagattaactcata -catggttgtattatgaattttcatctgcctaatgtactccaattcttgtttacaatcaat -tatataatcaaagagtgatgatgcatacacattacaaagtgaataatctaccatcataaa -atacttgatacagagctttatcacatcatggttttcaattgtattattaagtatagctaa -ttttatacagtcaatagacaatggttctctaagcaatatttctaatattttaagatgtgc -ttccctacgggcgatgacagatcccctatccacggccacgtcaagacatgtatatccatt -actcattactgcgttgacatttgctccattttctaatagccatgatactaaatctatata -acctgcatagatagcgcgataaagcaaggtccttccaccagcatctagttgattgatatc -ttcaatatatgggatacaaagcttataaatttctaatactgtgggttcatctacaaggaa -tcccctagtatactgaattattttatatagatctaatttaacatcattttcatctgggat -accacaattcaaaataaactcaacaacactactttcctttttacatattcccctaaaata -ggcattcaagcattctattttatatattacagccccatgatctaccataagatcaacaat -gtctatttctacatatgcattagatagatagtaaagtaagagatcttgcacagaattaca -attcttaataattatagagaaaatatcttccatataattctttgacactaatgcagatat -aatatctttatatgtaatatatgcaaacagtctatctactatatactgatcaatattatc -tctatgaatcctaaaataatcatacagaacatctacaggatcacaaattggttcaaggag -aaatctatcaaatattttcctgtcaacaactggttctagaacataacagtcaacacctaa -tccatgttttttataatcatctaccaaagataatgaccaaagatcgaggtcgtcgtgaaa -ctgctcatcgacagccatgaaatctaccgactccatggtgcgaatcgcactgtcttattc -gccattgattttcattttttataattatgtacatgttttccttctattctcaagagtcta -caaaaatatattttttcgatatctaagtactaagtttttttactgtttttgttactgtct -tccattcttctaactaaagatctgagataaattatacaatcttcgctatcgaaccatttt -tgtagtctaaagcctgaagtaattaaccaactgtttttattagtggcttttttcgatcta -tcctcgtcctctcatcatccttatattattatcattattatcatagtctattaaacacaa -atcatctacgtttataacaacattctcattattaattagttctgtagaatatctttaata -atttggctatacatctgttcaatactatctattgatgatttcttttttaagacttaaact -agttatggtaatgacgatgaaatcgagtagtaacttctaataaagacttgatatcattat -catatgtttgatcgtcatagttaatagtgtggctaaatggtactgttaataagtttatag -acaatatcatagtattttctttccagaattagattatttttttaaatactgatcctcaca -attccgtgatgtagcagtagttggtgcatggtctatatcgttaaaatgtatcatatataa -tagttttctgacgtggagtacagaattttcgattaatgagttcatggtaaggaagggcaa -atgcctgtatataatatacataagttaatagttttttatcatattttctaataccataat -aaaaattatcattattgcgtttggtagttctgccctatcatctatatcactgtcactctc -gctctcactatatcttctaaaattacaaacaactggatattcgataacagcatttgtgta -gtttttgtcttttacagtatatacgttattgtcaaaatctaaacaaatattagcataata -catctatctataagatcaggatccatgttcgagcatactagccatgtatatttgtaactt -cgtcgtacagcgttagatcaatagaataaacaatcgtgtgacgcaacttttttacgatct -agttgtatgagtttatcgtttacataagcaattaacggctttaacagatgatctgagtaa -taatatacctctgttatacgtttaatgttcacggtcttagtatttttagatatcaattgt -gatttacaccatattcgactcccttgtgtgtaacgttagaaattctaaatctatattatc -tattacagcgtaaaacacattcaatattgtattgttatttttatattatttacacaatta -acaatgtattattagtttatattactgaattaataatataaaattcccaatcttgtcata -aacacaaaatccattaaaaatgtcgataaaatatctgatgttgttgttcgctgctatgat -aatcagatcattagccgatagtggtaatgctatcgaaacaacatcgccagaaattacaaa -cgctacaacagatattccagctatcagattatgtggtccagagggagatggatattgttt -acacggtgactgtatccacgctagagatattgacggtatgtattgtagatgctctcatgg -ttatacaggtattagatgtcagcatgtagtattagtagactatcaacgttcaggaaaacc -agacactacaacatcatatatcccatctctaggtattgtgcttgtattagtaggcattat -tattacgtgttgtctattatctgtttatatgttcactcgaagaactaaactacctataca -agatatggttgtgttatattttttataaaatttttttatgagtatttttacaaaaatgta -tatgtataaaaaaaatactaagtatacgatgtatcctgtattatttgtatttatctaaac -aatacttctgcctctagatgggatacaaaaattttttatttcagcatattaaagtaaaat -ctagttaccttgaaaatgaatacagtgggtggttccgtatcaccagtaagaacataatag -tcgaatacagtatccgattgagattttgcatacaatactagtctagaaagaaatttgtaa -tcatcctctgtgacaggagtccatatatctgtatcatcgtctagtttttatcagtgtcct -atgctatattcctgttatcatcattagttaatgaaaataactctcgtgcttcagaaaagt -caaatattgtatccatacatatatctccaaaactatcacttatacgtttatctttaacga -acatatacctagatggttatttactaacagacattttttcaagatctattgacaataact -cctatagtttccacatcaaccaagtaatgatcatctattgttatataacaataacataac -tcttttccatttttatcagtatctatatcaacgtcgttgtagtgaatagtagtcattgat -ctattatatgaaacggatatgtctagttaatattttctttgatttaaagtctatagtctt -tacaaacataatatccttatccgactttatatttcctgtagggtggcataattttattct -gcctccacaatcagtgtttccaaatatattactagacaatattccatatagttattagtt -aagggacccaattagaacacgtacgcgcttattcatcatttggatcgtatttcataaaag -ttattatgttatagatgtcaacacattctacatttttttaattgtctatatagtattttt -ctgatattttctataatatcagaattgtcttccataggaagttgtatactattcggaatc -agttacatgtttaaataattctctgatgtcattccttatacaatcaaattcattattaaa -cagtttaatagtctgtagacctttatcgtcgtacatatccattgtcttattagttacgct -tatttttatgggttttacgttgctttattatattttataataatgattgtttgacaatgt -cgtagtatagatatattattagaggaggtataattataaaaagtttctgagtacgatgtt -ataagaggagaggacacattaacatcatacatcaattaactacattcttataacattgta -atcaaaagaattgcaattttgatgtataacaactgtcaatggaattgtatattacaaatt -acggtatgttgtaacaacaaataccgatcggtaattgtctctgccgctgtaatagaatta -attatatatctattacaccggccttgtatcataataaagttgtggtagtatgatctccat -atttataatttagtactttgtatttagtttttttggaatcataaaaaaagttttactaat -ttaaaatttaaaaagtatttacatttttcactgtttagtcgcggatatggaattcgatcc -tgtcaaaatcaatacatcatctatagatcatgtaacaatattacaatacatagatgaacc -aaatgatataagactaacagtatgcattatccgaaatgttaataacattacatattatat -caatatcacaaaaataaatccacatttggctaatcgatttcgggcttggaaaaaacgtat -cgccggaagggactatatgactaacttatctagagatacaggaatacaacaatcaaaact -tactgaaactatacgtaactgtcaaaaaaataaaaacatatatggtctatatatacacta -caatttagttattaatgtggttattgattggataaccgatgtgattgttcaatcaatatt -aagagggttggtaaattggtacatagctaataatacatatactccaaatacacccaataa -tactacaaccatttctgagttggatatcatcaaaatactggataaatacgaggacatgta -tagagtaagtaaagaaaaagaatgtggaatttgctatgaagttgtttactcaaaacgatt -agaaaacgatagatactttggtttattggattcgtgtaatcatatattttgcataacatg -tatcaatatatggcatagaacacgaagagaaaccggtgcgtcagataattgtcctatatg -ccgtacacgttttaaaaaaataacaatgagcaagttctataagctagttaactaataaat -aaaaagtttaattatcgacgatatatgtcgttatttttctctcatatgaaagattaattt -gattctaatataatcttcagtattggatgaatctcaattcaaattaattccattagatta -gattagattagatcataaataaaaatagtagcacgcactacttcagccaaatattctttt -ttgaaacgccatctagcgtaatgagaacacaagtgaacctataatgagcaaatttattag -tatcggttacatgaaggactttacgtagagtggtgattcctccatctgtggtacgaacgg -tttcatcttctttgatgccaccacccagatgttctataaacttggtatcctcgtccgatt -tcatatcatttgccaaccaatacatatagctaaacccaggcatacgttccacacatccgg -aacaatgaaattctccagaagatgttacaatggctagatttggacatttggtttcaaccg -cgttaacatatgagtgaacacacccatacatgaaagcgatgagaaataggattctcatct -tgccaaaatatcactataaaaaatttatttatcaattttaaaggtataaaaaaatactta -ttgttgctcgaatattttgtatttgatggtatacggaagattagaaatgtaggtattatc -atcaactgattttatgatggttttatgaattttattatgcttcactattgcatcggaaat -aatatcatatgcttccacgtatattttattttgttttgactcataatacgcacgtaattc -tggattattggcatatcgatgaataattttagctccatgctcagtaaatattaatgagaa -catagtgttgcctcctaccattatttttttcatctcattcaattcttgattgcagagatc -tatataatcattatagcgttgacttatggactctggaatcttagacgatgtacagtcatc -tataatcatggtatatttaatacattgttttatagcataggcattatctacgatattaga -tacttcactcaatgaatcaatcacacaatctaatgtaggtttatgacataatagcatttt -cagcagttcaatgtttctagattcgttgatggcaatggttatacatgtatatccgttatt -tgatctaatgttgacatctgaaccggattctagcagtaaagatactagagattgtttatt -atatctaacagccttgtgaagaagtgtttctcctcgtttgtcaatcatgttaatgtcttt -aagataaggtagacaaatgtttatagtactaagaattgggcaaacataagacatgtcaca -aagaccctttttgtatgtataagtgtagaaattataacatccatagttggattcacatag -gtgtccaatcgggatctctccatcatcgagatgattgacggcatctcccccttccttttt -tagtagatatttcatcgtgtaagaatcaatattaatatttctaaagtatctgtgtatagc -ctctttatttaccacagctccatattccaacatgcattccactagagggatatcgatatc -gccgaatgtcatatactcaattagtatatgttggaggacatccgagttcattgttttcaa -tatcaaagagatggtttccttatcatttctccatagtggtacaatactacacattattcc -gtacggctttccattctccaaaaacaattttaccaaatctaaatctacatctttattgta -tctataatcactatttagataatcagccataattcctcgagtgcaacatgttagatcgtc -tatatatgaataagccgtgttatctattcctttcattaacaatttaacgatgtctatatc -tatatgagatgacttaatataatattgaagagctgtacaatagtttttatctatagaaga -cggcttgattccgtgattaattagacatttaacaacttccggacgcacatatgctctcgt -atccgactctgaatacagatgagcgatgatatacagatgcaatacggtaccacaatttcg -tggttgataatcatcatacacgtatccgtactcgtcatcctcataaagaacactgcatcc -attttctatgaacaaatcaataatttcaggaacaggatcatctgtcattacataattttc -tataactgaacgatggttttcacatttaacactcaagtcaaatccatgttctaccaacac -ctttatcaagtcaacgtctacattttttgatttcatatagctgaatatattaaagtcatt -tatgttgctatatccagtagcttctagtagagccatcgctatatccttattgactttaac -atgtctactatttgtgtattcttctattggggtaaactgtctccaatttttatgtaatgg -attagtgccactatctagtagtagtttgacgacctcaacattattacaatgctcattgaa -aaggtatgcgtgtaaagcattattcttgaattggttcctggtatcattaggatctctgtc -tctcaacatctgtttaagttcatcgagaaccacctcctcattttccagatagtcaaacat -tttgactgaatagaagtgaatgagctactgtgaactctatacacccgcacaactaatgtc -attaaatatcatttttgaatgtatttataccatgtcaaaaacttgtacaattattaataa -aaataattagtgtttaaattttaccagttccagattttacacctccgttaacacctccat -taaccccactttttacaccactggacgatcctcctccccacattccactgccactagatg -tataagttttagatcctttattactaccatcatgtccatggataaagacactccacatgc -cgccactactaccccctttagacgacatattaataagacaagtttaacaataaaattaat -cacgagtaccctactaccaaccactattatatgattacagtaccttgactaaagtctcta -gtcacaagatcaatactaccaacctacgctattatatgattatagtttctatttttatag -gaacgcgtacgagaaaatcaaatgtctaagttctaacggtagtgttgataaacgattgtt -atccgcggatacctcatctatcatgttgtctattttcttactttgttctattaacctatt -agcattatatattatttgattataaaacttatattgcttattagcccaatctgtaaatat -cggattattaacatatcgtttctttgtaggtttatttaacttgtacatcactgtaagcat -gtccgtaccatttattttaatttgacacatatcagcaatttctttttcgcagtcggttat -atattctatataagatggatacgtatcacatatgtacttatagtctactaatatgaagta -cttaatacatattttcagtaacgatttagccttattacctattaataagtgcctgtcgtt -ggataggtaatcaactgttttcttaatacattcgatggttggtaatttactcaaaataat -ttccaatatcttaatatatatttctgctatttctggtatacatgcatgtgccattataac -acaaataccaatacatgtagacccatatgttgttgttatattaatatctgcgccattatc -tattaaccattctattaggtcaacactatgcgactcgatacaataataaagtatactacg -tccatgtttatctattttgtttatatcatcgatatacggcttacaaatttctagtatcga -taacacttctgactcgtgaataaataaggtagggaataacggcataatatttattatgtt -atcatcattaacaactacgtttccattttttaaaatatactctacaactttaggatccct -attgtcaaatcttttaaaatatttatttatatgcttaaatctatataatatagctccttc -cctaatcatacatttgataacattgatgtacactgtatgataagatacatattctgacaa -tagatcttgtatagaatctgtatatcttttaagaattgaggatattatgacattattacg -taaactattacacaattctaaaatataaaatgtatcatgggcagataatagtttatccac -tatataattatctattttatgatttttcttcctatattgtttacgtaaatagatagatag -aatatgcattagttcattaccgctatagttactatcgaataacacgtcaaatatttcccg -tttaatatcgcatttgtcaacataataatagagtatggtacgttcacgataagtataatg -acacatctcgttttcgtgcgaaattaaatagtttatcacgtccaaagatgtcacataacc -atcttgtgacctagtaataatataataatagagaactgttttacccattctattatcata -atcagtggtgtagtcataatctaaataatcaaactcgtcatcccaattaaaataaatata -atcagtacattgaatgggtatgatattgtacccatactgtatgttgctacatgtaggtat -tcctttatccaataatagtttaaatacatctatattaggatttgatgttgtcgcgtattt -ctctacaatattaataccatttttgatactatttatttctatacctttcgaaattagtaa -tttcaataagtctatatcgatgttatcagaacatagatattcaaatatatcaaaatcatt -gatatttttatagtcgactgacgacaataacaaaatcacaacatcgtttttgatattatt -attttttttggtaacgtatgcctttaatggagtttcaccatcatactcatataatggatt -tgcaccactttctattaatgattgtgcactactggcatcgatgttaaatgttttacaact -atcatagagtatcttatcgttaaccatgattggttgttgatgttatcacattttttggtt -tctttcatttcagttatgtatggatttagcacgtttgggaagcatgagctcatatgattt -cagtactgtagtgtcagtactattagtttcgatcagatcaatgtctagatctatagaatc -aaaacacaataggtcagaagataatgaatatctgtacgcttcttcttgtactgtaacttc -tggttttgttagatggttgcatcgtgctttaacgtcaatggtacaaattttatcctcgct -ttgtgtatatcatattcgtctctagtataaaattctatattcaaattatcatgcgatgtg -tgtacgctaacggtatcaataaacggagcacagcatttagtcaacagtaatccaaaattt -tttaaagtatatcttaacgaaagaagttgtcatcgttagagtgtggtaaatcattgtcta -cggtactagatcctcataagtgtatatatctagagtaatatttaatttatcaaatggttg -ataatatggatgttgtggcaatttcctaatacggaaataagacataaacacgcaataaat -ctaattgcggacatgttacactccttaaaaaatacgaataaacactttggcttttagtaa -gtgtcatttaacactatactcatattaatccatggactcataatctctatacgggattaa -cggatgttctatatacggggatgagtagttctcttctttaactttatactttttactaat -catatttagactgatgtatgggtaatagtgtttgaagagctcgttctcatcatcagaata -aatcaatatctctgtttttttgttatacagatgtattacagcctcatatattacgtaata -gaacgtgtaatctaccttattaactttcaccgcatagttgtttgcaaatacggttaatcc -tttgacctcgtcgatttccgaccaatctgggcgtataatgaatcttaactttaatttctt -gtaatcattcgaaataatttttagtttgcatccgtagttatctcctctatgtaactgtaa -atttctcaacgcgatatctccattaataatgatgtcgaattcgtgttgtatacccatact -gaattgatgaactaataccgacggtattaatagtaatttacttttcatctttacatactt -ggtaatagttttactatcataagtttataaattccacaagctactatggaatataccaac -catcttagtatagaacacatgtcttaaagttattaattaattacatgttgttttatatat -cgctacgaatttaaacagaggaatcagttaggaagaaaaaattatctgtcatcatcatca -tctattggataacatctctgtattctacgatagagtgctattttaagatgtgacagatcc -gtgtcatcaaatatatactccattaaaatgattattccggcagcgaacttgatattggat -acatcacgacctttgttaatatccacgacaatagacagcaatcccattgttccataaaca -gtgagtttatctttctttgaagtgatattttgtagagatcttataaaactgtcgaatgac -atcgtatttatatctttagctaaatcatatatgttaccatcataatatctaacagcatct -atcttaaacgtttccatcgctgtaaagacgtttccgatagatggtctcgtttcatcagtc -atactgagccaacaaatgtaatcgtgtataacatctttgatagaatcagactctaaagaa -aaggaatcggctttattatacacattcatgataaacttaatgaaaaatgtttttcgttgt -ttaagttggatgaatagtatgtcttaataattgttattatttcactaattaatatttagt -aacgagtacactctataaaaacgagaatgacataactaatcataactagttatcaaagaa -tgtctaggacgcgtaattttttatggtatagatcctgtaagcgttgtctgtattctggag -ctattttctctatcgcattagtgagttcagaatatgttataaatttaaatcgaataacga -acataactttagtaaagtcgtctatattaactcttttattttctagccatcgtaatacca -tgtttaagatagtatattctctagttactacgatctcatcgttgtctagaatatcgcata -ctgaatctacatccaattttagaaattggtctgtgctacatatctcttctatattattgt -tgatgtattgtcgtagaaaactattacgtagaccattttctttataaaacgaatatatag -tactccaattatctttaccgatatatttgcatacataatccattctctcaatcactacat -ctttaagagtttggttgttaagatatttggctaaactatataattctattagatcatcaa -cagaatcagtatatatttttctagatccaaagatgaactctttggcatcctctataatat -tatcagaaaagatattttcgtgttttagtttatcaagatttaacctgttcatatccatga -ttaacgacgtcatataaccacataaaataaaaatccattttcatttttagcacaatacta -ttcataattgatattgatgtaatattttgttactttgaacgtaaagacagtacacgggtc -cgtatctccaacaagcacgtagtaatcaaatttggtgttgttaaacttcgcaatattcat -caatttagatagaaacatatactcatcatctgttttaggaatccatgtattattaccact -ttccaacttatcattatcccaggctatgtttcgcccatcatcgttgcacagagtgaataa -ttcttttgtattcggtagttcaaatatatgatccatgcatatatcgacaaagctattgta -gatgtgatttttcctaaatctaatataaaactcgtttactagcaaacattttcctgattt -atcgaccaagacacacatggtttctaaatctatcaagtggtggggatccatagttataac -gcagtaacataaattattaccttcttgactgtcgctaatatctatatacttattgttatc -gtattggattctacatatagatggcttgtatatcaaagatatagaacacataaccaattt -atattctcgctttgtattttcgaatctaaagttaagagatttagaaaacattatatcatc -ggatgatgatatcactgtttccagagtaggatatattaaagtctttaaagattttgtccg -attcaaataaatcactaaataatatcccatattatcatctgttatagtcgtgtcattaaa -tctattatattttatgaaagatatatcactgctcacctctatatttcgtacatttttaaa -ctgtttgtataatatctctctaatacaatcagatatatctattgtgtcggtagacgatac -cgttacatttgaattaatggtgttccattttacaacttttaacaagttgaccaattcatt -tctaatagtatcaaactctccatgattaaatattttaatagtatccattttatatcacta -cggacataaaccattgtatattttttatgtttattagtgtacacattttggaagtaagtt -cctggatcggatgtcaccgcagtaatattgttgattatttctgacatcgacgtattatat -agttttttaattccatatcttttagaaaagttaaacatccttatacaatttgtggaatta -atattatgaatcatggtttttacacatagatctattacaggcggaacatcaattattatg -gcagcaactagtatcatttctacattgtttatggtgatgtttatcttcttccagcgcata -tagtctaatatcgattcaaacgcgtgatagtttataccattcaatataatcgcttcatcc -tttagatggtgatcctgaatgtgtttaaaaaattatacggagacgccgtaataatttccc -cattgatagaaaatatcacgctttccattttcttgaagtactaaaagtaattataatata -atgtaaaggtttatatattcaatattttttataaaaaaaatcattttgacattaattcct -ttttaaatttcagtctatcatctatagaaacatattctatgaatttataaaatgctttta -cgtatcctatcgtaggtgatagaaccgctaaaaaacctatcgaatttctacaaaagaatc -tgttatatggtatagggagagtataaaacattaaatgtccgtacttattaaagtattcag -tagccaatcctaactctttcgaataattattaatggctcttattctgtacgaatctattt -ttttgaacaatggacctagtggtatatcttgttctatgtatctaaaataatgtctgacta -gatccgttagtttaatatccgcagtcatcttgtctagaatggcaaatctaactgcgggtt -taggcgtaggcgttagtttagtttctatatctacatctatgtctttatctaacaccaaaa -atataatagctaatattttattacaatcatccggatattcttctacgatctcactaacta -atgtttctttggttatactagtatagtcacgatcagacaaataaagaaaatcagatgatc -gatgaataatacatttaaattcatcatctgtaagatttttgagatgtctcattaaaatat -tattagtgtcagttctcattatcatatattgacagcagctattacacttattttattttt -ctgtattttattacttttcaccatatagatcagtcattagatcatcaaaatacttttcaa -tcatcctaaagagtatggtgaacgaatcttcccatctaatttctgaacgtctaccaatgt -ctctagccactttggcactaatagcgatcattcgcttaacatcttctacattattaactg -gttgattcaatctatctagcaatggaccgtcggatagcgtcattctcatgttcttaatca -atgtacatacatcgtcatcatctaccaattcatcaaacaatataagctttttaaaatcat -cattataataggatggatcgccgtcatttctccaaagaatatatctaataagtagagtcc -tcatgcttagtaatttaactattttagttaacaactattttttatgttaaatcaattagt -aacaccgctatgtttaatacttattcatattttagttttaggatcgagaatcaatacaaa -aattaatacatcaattttggaaatacttagtttccacgtagtcaatgaaacatttgagct -catcgtaaaggacgttctcgtacaagacgtaactataaattggtttatatttgttcaaga -tagatacaaatccgataacttttttgacgaattctacgggattcactttaaaagtgtcat -accgggttctttttattcttttaaacagatcgattgtgtgatgttgattaggtcttttac -gaatttgatacagaatagcgtttacatatccaccatagtaatcaatagccatttgttcgt -atgtcataaattctttaattatatgacactgtgtattatttagttcgtccttgttcatca -ttaggaatctatccaatatggcaattatattagaactataactgcgttgtatgcgcatgt -tgatgtgtctgtttatacaatcaattatactaggatccataccactacaatcgggtaaaa -ttgtagcatcatataccatttctagtactttagattcattgttatccattgcagaggacg -tcatgatcgaatccaaaaaaatatattatttttatgttattttgttaaaaataatcatca -aatacttcgtaagatactccttcatgaacataatcagttacaaaacgtttatatgaagta -aagtatctacaatttttacaaaagtcaggatgcataagtacaaagtacgcgataaacgga -ataataatagatttatctagtttatctttttctatctctttcatagttatatacatggtc -tcagaagtcggattatgtaacatcagcttcgataaaatgactgggttatttagtcttaca -cattcgctcatacatgtatgaccgttaactatagagtctacactaaaatgattgaataat -agatagtctaccattgtttcgtattcagatagtacagcgtagtacatggcatcttcacaa -attatatcattatctaatagatatttgacgcatcttatggatcccacttcaacagccatc -ttaaaatcggtagaatcatattgctttcctttatcgttaataatttctagaacatcatct -ctatcataaaagatacaaatattaactgtttgatcagtaataacattgctagtcgatatc -aatttgttaataagatgcgctgggctcaatgtcttaataagaagtgtaagaggactatct -ccaaatttgttttgtttattaacatccgttgatggaagtaaaagatttataatgtctaca -tacttgactgttttagagcatacaatatggagaggcgtatttccatcatgatctggtttt -gagggactaattcctagtttcatcatccatgagattgtagaagcttttggattgtctgac -ataagatgtctatgaatatgatttttgccaaatttatccactatcctggcttcgaatccg -atagacattatttttttaaacactctttctgaaggatctgtacacgccaacaacggacca -catccttcttcatcaaccgagttgttaatcttggctccatactgtaccaataaatttatt -ctctctatgacttcatcatctgttcccgagagataatatagaggtgttttattatgttta -tcacatgcgtttggatctgcgccgtgcaccagcagcatcgcgactattctattattatta -attttagaagctatatgcaatggataatttccatcatcatccgtctcatttggagagtat -cctctatgaagaagttcttctataaatcgttcatctagtcctttaatgccacaatacgca -tgtagaatgtgataatttccagagggttcgataacttgtagcatattcctaaatacatct -aaatttttactattatatttggcataaagagatagataatactcgaccgacataatgttg -tgttgtccattatagtataaaaattaatatttctatttctatatatttgcaacaatttac -tctctataacaaatatcataacttagttcttttatgtcaagaaggcactggtttaattca -tctataaatgtcactccataactaccacgcatactatactcagaattatgataaagatat -ttattcttggggtgtaagtaatggggattaatctttgttggatcagtctctaagttaaca -catgtcacacatgatccatttatagttatatcacacgatgatgatttatgaattgattcc -ggaagatcgctattgtattttgtagttccacaattcatttccatacatgttattgtcaca -ctaatattatgatgaactttatctagccgctgagtggtaaacaacagaacagatagttta -ttatctttaccaacaccctcagccgctgccacaaatctctgatccgtatccatgatggtc -atgtttacttttagtccgtatccagtcaacactatgttagcatttctgtcgatatagctt -tcactcatatgacactcaccaataattgtagaattaatgtcgtaatttacaccaatagtg -agttcggcgacaaagtaccagtaccggtaatcttgtcgatgaggacatatagtattcttg -tattctaccgaatacccgagagatgcgatacaaaagagtaagactaatttgtaaaccatc -ttactcaaaaatatgcgacaataggaaatctatcttatacacataattattctatcaatt -ttaccaattagttagtgtaatgttaacaaaaatgtgggataatttaatagtttttcctta -cacaattgacatacatgagtctgagttcctcgtttttgctaattatttcgtccaatttat -tattcttgacatcgtcaagatcttttgtataggagtcagacttgtattcaacatgttttt -ctataatcatcttagctatttcggcatcatccaatagtacattttccagattaacagaat -agatattaatgtcgtatttgaacagagcctgtaacatctcaatgtctttattatctatag -ccaatttgatgtccggaatgaagagaagggaattggtgtttgttgacgtcatatagtcga -gcaagagaatcatcatatccacgtgtccattttttatagtggtgtgaatacaactaagga -gaatagccagatcaaaaggagatggtatctctgaaagaaagtaggaaacaatacttacat -cattaagcatgacagcatgataaaatgaagttttccatccagttttcccatagaacatca -gtctccaatttttcttaacaaacagttttaccgtttgcatgttaccactatcaaccgcat -aatacaatgcggtgtttcctttgtcatcaaattgtgaatcatccattccactgaatagca -aaatctttactattttggtatcttctaatgtggctgcctgatgtaatggaaattcattat -ctagaagatttttcaatgctccagcgttcaacaacgtacatactagacgcacgttattat -cagctattgcataatacaagacactatgaccattgatatccgccttaaatgcatctttgc -tagagagaaagcttttcagttgcttagacttccaagtattaattcgtgacagatccatgt -ctgaaacgagacgctaattagtgtatattttttcattttttataattttgtcatattgta -ccagaattaataatatctctaatagatctgattagtagatatatggctatcgcaaaacaa -catatacacatttaataaaaataatattcattaagaagattcagattccactgtacccat -caatataaaataaaataattattccttacatcgtacccataaacaatatattaagtatat -tccaccttacccataaacaatataaatccagtaatatcatgtctaatgatgaacacaaat -ggtgtattaaattccagttcttcaggagatgatctcgccgtagctaccatgatagtagat -gcctccgctacagttccttgttcgtctacatctatctttacattctgaaacattttataa -atatataatgggtccctagtcatatgtttaaacgacgccttatctggattaaacatacta -ggagccatcatttcggctatcgacttaatatccctcttgttttcgatagaaaatctaggg -agtttaagattgtacattttattccctaattgagatgaccaatattctaattttgcaggc -gtgatagaatctgtgaaatgggtcatattatcacctattgccaggtacatactaatatta -gcatccttatacagaaggcgcaccatatcatattcttcgtcatcgattgtgattgtattt -ccttgcaatttagtaactacgttcatcatgggaaccgttttcgtaccgtacttattagta -aaactagcattgtgtgttttagtgatatcaaacggatattgccacgtacctttaaaatat -atagtattaatgattgcccatagagtattatcgtcgagcatagtagaatcaactacatta -gacataccagatctacgttctactatagaattaattttattaaccgcatctcgtctaaag -tttaatctatataggccgaatctatgatattgttgataatacgacggtttaatacacaca -gtactatcgacgaaactttgatacgttagatctgtgtacgtatatttagatgttttcatc -ttagctaatccggatattaattctgtaaatgctggacccagatctctttttctcaaattc -atagtattcaataattctactctagtattacctgatgcagacaatagcgacataaacata -gaaaacgaatacccaaacggtgagaagacaatattatcattatcatcctcatccccattt -tgaatatttttatacgctaatataccagcattgataaatccctgcagacgatatgcggat -actgaacacgctaatgatagtatcaataacgcaatcatgatttttatggtattaataatt -aaccttatttttatgtttggtataaaaattattgatgtctacacatcctttataatcaac -tctaatcactttaacttttacagttttccctacaagtttatccctatattcaacatatct -atccatatgcatctcttaacactctgccaagatagcttcaaagtgaggatagtcaaaaag -ataaatatatagagtataatcattctcgtatactctgccctttattacatcgcccgcatt -gggcaacgaataacaaaatgcaagcatcgtgttaacgggctcgtaaattgggataaaatt -atgtttttattgtttatctattttattcaagagaatattcaggaagttccttttctggtt -gtatctcgtcgcagtatatatcatttgtacattgtttcatattttttaatagtctacacc -ttttagtaggactagtatcgtacaattcatagctgtattttgaattccaatcacgtataa -aaatatcttccaattgttgacgaagacctaatccatcatccggtgtaatattaatagatg -ctccacatatatccgtaaagtaatttcctgtccaatttgatgtacctatatacgccgttt -tatcggttaccatatattttgcatggtttaccctagaatacggaatgggaggatcagcat -ctggtacaataaatagctttacttctatatctatgtttttagattttagcatagctatag -atcttaaaaagtttctcatgataaacgaagatcgttgccagcaactaatcaatagcttaa -cggatacttgtctgtctatagcggatcttcttaattcatcttctatataaggccaaaaca -aaattttacccgcctttgaataaataataggaataaagttcataacagatacataaacga -atttactcgcatttccgatacatgacaataaagcggttaaatcattggttctttccatag -tacataattgttgtggtgcagaagcaataaatacagagtgtggaacaccgcttacgttaa -tactaagaggatgatctgtattataatacgacggataaaagtttttccaattatatggta -gattgttaactccaagataccagtatacctcaaaaatttgagtgagatccgctgccaagt -tcctattattgaagatcgcaatacccaattccttgacctgagttagtgatctccaatcca -tgttagcgcttcctaaataaatatgtgtattatcagatatccaaaattttgtatgaagaa -ctcctcctaggatatttgtaatatctatgtatcgtacttcaactccggccatttgtagtc -tttcaacatcctttaatggtttgttggatttattgacggctactctaactcttactcctc -ttttgggtaattgtacaatctcgtttaatattaccgtgccgaaattcgtacccacttcat -ccgataaactccaataaaaagatgatatatctagtgtttttatggtattggatagaattt -ccctccacatgttaaatgtagtcaaatatactttatcaaattgcatacctataggaatag -tctctgtaatcactgcgattgtattatccggattcattttatttgttaaaaaaataatcc -tatatcacttcactctattaaaaatccaagtttctatttctttcatgactgattttttaa -cttcatccgtttccttatgaagatgatgtttggcgccttcataaatttttatttccctat -tacaatttgcatgttgcatgaaataatatgcacctgaaacatcgctaatctcattgtttg -ttccctggagtatgagagtcggggtgttaatcttgggaattatttttctaaccttgttgg -tagccttcaagacctgactagcaaatccagccttaattttttcatgattgactaatggat -cgtattggtatttataaacttcatccatatctctagatactgattctggacatagctttc -cgactgacgcatttggtgtaatggttcccataagttttgcagctagcagattcagtcttg -gaacagcgtctgcattaactagaggagacattagaatcattgctgtaaacaagtttggat -tatcgcaagcagctagtatagaaattgttgctcccatggaatgacccaataagaagactg -gaactcctggataagtagatttaatagtcaccacgtgctgtaccacatctctaacatact -taccaaagtcatcaatcatcattttttcaccattacttcttccatggccaatatgatcat -gtgagaatactaaaattcctaacgatgatatgttttcagctagttcgtcataacgtccag -aatgttcaccagctccatgacttatgaatactaatgccttaggatatgtaataggtttcc -aatatttacaatatatgtaatcattgtccagattgaacatacagtttgtactcatgattc -actatataactatcaatattaacagttcgtttaatgatcatattatttttatgttttatt -gataattgtaaaaatatacaattaaatcaatatagaggaaggagacggtactgtattttg -tgagatagtaatggagactaaatcagattatgaggatgctgttttttactttgtggatga -tgatgaaatatgtagtcgcgactccatcattgatctaatagatgaatatatcacgtggag -aaatcatgttatagtgtttaataaagatattaccagttgtggaagactgtacaaggaatt -gataaagttcgatgatgtcgctatacggtactatggtattgataaaattaatgagattgt -cgaggctatgagtgaaggagaccactacatcaatcttacagaagtccatgatcaggaaag -tctattcgctaccataggaatatgtgctaaaatcactgaacattggggatacaaaaagat -ttcagaatctaaattccaatcattgggaaacattacagatctgatgaccgacgataatat -aaacatcttgatactttttctagaaaaaaaaatgaattgatgatataagtgtcttcataa -cgcattattacgttagcattctattatccagtgttaaaaaaattatcctatcatgtattt -gagagtcttatatgtagcaaacatgataactgcaatacccataatctttagatattcacg -cgtgctatggatggcattatcccgcggtgcggaaatgtacgttatataatctacaaaata -atcatcgcatatagtatgagatagtagagtaaacatttttatcgtttctactgggttcat -acatcgtctacccaattcggtaatgaatgaaattgtcgccaatcttacacccaaaccctt -gttgttcattagtatagtattaacttcattatttatgtcataaactgtaaatgattctgt -agatgccatatcacacatgatattcatgtcactattataatcattattaactttatcaca -atacgtgttgataatatctacatatgatctagtttttgtgggtaattgtctatacaagtc -gtctaaacgttgtttactcatatagtattgaacagccatcattacatggtcccgttccgt -tgatagataatcgagtatgttagtagacttgtcaaatctatataccatattttctggaag -cggatatacatagtcgcgatcatcattatcactagcctcatcctctatatcatgtacatg -tacataatctatgatattattatacataaacatcgacaacatactattgtctattatcta -agtcctgttgatccaaacccttgatctcctctatctgtactatctagagattgtacttct -tcaagttctggataatatatacgttgatagattagctgagctattctatctccagtattt -acattaaacgtacattttccattattaataagaatgactcctatgcttcccctataatct -tcgtctattacaccgcctcctatatcaatgccttttagggacagaccagacctaggagct -attctaccatagcagaacttaggcatggacatactaatatctgtcttaattaactgtcgt -tctccaggagggatagtataatcgtaagcgctatacaaatcatatccggcagcacccggc -gattgcctagtaggtgatttagctctgttagtttccttaacaaatctaactggtgagtta -atattcatgttgaacataaaaaatatcattttatttcaaaattatttaccattccattcc -atcccatatattccatgaataagtgcgattattgtacacttctatagtatctatatacga -tccacgataaaatcctcctatcaatagcagtttattatccactatgatcaattctggatt -atccctcggataaataggatcatctatcagagtccatgtattgctggattcacaataaaa -ttccgcatttctaccaaccaagaataaccttctaccaaacactaacgcacatgatttata -atgaggataataagtggatggtccaaactgccactgatcatgattgggtagcaaatattc -tgtagttgtatcagtttcagaatgtcctcccattacgtatataacattgtttatggatgc -cactgctggattacatctaggtttcagaagactcggcatattaacccaagcagcatcccc -gtggaaccaacgctcaacagatgtgggatttggtagacctcctactacgtataatttatt -gttagcgggtatcccgctagcatacagtctggggctattcatcggaggaattggaatcca -attgtttgatatataatttaccgctatagcattgttatgtatttcattgttcatccatcc -accgataagatatactacttctccaacatgagtacttgtacacatatggaatatatctat -aatttgatccatgttcataggatactctatgaatggatacttgtatgatttgcgtggttg -tttatcacaatgaaatattatgttacagtctagtatccattttacattatgtatacctct -gggagaaagataatttgacctgattacatttttgataagaagtagcagatttcctaatct -atttcttcgcctcatataccacttaatgacaaaatcaactacataatcctcatctggaac -atttagttcgtcgctttctagaataagtttcatagatagataatcaaaattgtctatgat -gtcatcttccagttccaaaaagtgtttggtaataaagtctttagtatgacataagagatt -ggatagtccgtattctatacccatcatgtaacactcgatacaatattcctttctaaaatc -tcgtaggataaagtttatacaagtgtagatgataaattctacagatgttaatatagaagc -acgtaataaattgacgacgttatgactatctatatatacctttccagtatatgagtaaat -aactatagaagttagactgtgaatgtcaaggtctagacaaaccctcgtaactggatcttt -attttttgtgtatttttggcgtaaatgtgtgcaaaagtatggagataactttttcaatat -cgtagaattgactattatattacctcctatagcttcaataattgttttgaatttcttagt -cgtgtacaatgctaatatattcttacagtacacagtattgacaaatatcggcatttatgt -ttctttaaaagtcaacatctaaagaaaaatgattgtcttcttgagacataactcccattt -tttggtattcacccacacgtttttcgaaaaaattagtttttccttccaatgatatatttt -ccatgaaatcaaacggattggtaacattgtaaatttttttaaatcccaattcagaaatca -atctatctgcgacgaattctatatatgttttcatcatttcacaattcattcctatgagtt -taactggaagagccacagtaagaaattcttgttcaatggataccgcatttgttataataa -atctaacggtttcttcactcggtggatgcaataaatgtttaaacatcaaacatgcgaaat -cgcagtgcagaccctcgtctctactaattaattcgttagaaaacgtgagtccgggcatta -ggccacgctttttaagccaaaatatggaagcgaatgatccggaaaagaagattccttcta -ctgcagcaaaggcaataagtctctctccataaccggcgctgtcatgtatccacttttgag -cccaatcggccttcttttttacacaaggcatcgtttctatggcattaaagaggtagtttt -tttcattactatctttaacataagtatcgatcaaaagactatacatttccgaatgaatgt -tttcaatggccatctgaaatccgtagaaacatctagcctcggtaatctgcacttctgtac -aaaatcgttctgctaaattttcattcactattccgtcactggctgcaaaaaacgccaata -catgttttataaaatatttttcgtctggtgttagtttattccagtcattgatatctttag -atatatccacttcttccactgtccaaaatgatgcctctgcctttttatacatattccaga -tgtcatgatattggattgggaaaataacaaatctatttggatttggtgcaaggataggtt -ccataactaaattaacaatagtagtaattttttttcagttatctgtatgacgactgtact -tggatcttttgtatatcgctatcgccgcaatcactacaataattacaagtattattgata -gcattgttattactactatcataattaaattatcgacattcatgggtgttgaataatcgt -tatcatcattttgtaattgtgacgtcatactagataaatcatttgtgagattgttgtggg -aagcgggcacggaagatgcattatcattattatttaacgcctcccattcggattcacaaa -tgttacgcacgttcaaagttttatggaaactataattttgtgaaaacagataacaagaaa -actcgtcatcgttcaaatttttaacgatagtaaaccgattaaacgtcgagctaatttcta -acgctagcgactctgttggatatgggtttccagatatatatcttttcagttcccctacgt -atctataatcatctgtaggaaatggaagatatttccatttatctactgttcctaatatca -tatgcggtggtgtagaaccattaagcgcgaaagatgttatttcgcatcgtattttaactt -cgcaataatttctggttagataacgcactctaccagtcaagtcaatgatattagccttta -cagatatattcatagtagtcgtaacgatgactccatcttttagatgtgatactcctttgt -atgtaccagaatcttcgtacctcaaactcgatatatttaaacaagttaatgatatattaa -cgcgttttatgaatgatgatatataaccagaagttttatcctctgtggctagcgctataa -ccttatcattataataccaactagtgtaattaatatgtgacatgacagtgtgggtacaaa -tatgtacattatcgtctacgtcgtatttgatacatccgcattcagccaacaaatataaaa -ttacaaaaactctaacgacgtttgtacacatcttgatgcggtttaataaatgttttgatt -tcaatttattgtaaaaaaagattcggttttatactgttcgatattctcattgcttatatt -ctcatctatcatctccacacagtcaaatccatggttaacatgtacctcatcaaccggtaa -aagactatcggattcttctatcatcataactcgagaatatttaatttggtggtcattatt -aatcaagtcaattatcttatttttaacaaacgtaagtattttactcatttttttataaaa -acttttagaaatatacagactctatcgtgtgtctatatcttctttttatatccaatgtat -ttatgtctgatttttcttcatttatcatatataatggtccaaattctacacgtgcttcgg -attcatccagatcattaaggttcttataatcgcaacatccttctcttccatcttctacat -cttccttcttattcttagcgtcacagaatctaccacagcaggatcccatgacgagagtca -cattaaactaattcattttcaattataatatactgattagtaatgacaattaaaataaaa -atattcttcataaccggtaagaaagtaaaaagttcacattgaaactatgtcagtagttat -acatcatgagatgatatactctattttggtggaggattatatgatataattcgtggataa -tcattcttaagacacatttcttcattcgtaaatcttttcacattaaatgagtgtccatat -tttgcaatttcttcatatgatggcggtgtacgtggacgaggctgctcctgttcttgtagt -cgtcgactgtcgtgtttgcgtttagatccctccattatcgcgatcgcgtagtgagtacta -tttataccttgtaattaaatttttttattaattaaacgtataaaaacgttccgtatctgt -atttaagagccagatttcgtctaatagaacaaatagctacagtaaaaataactagaataa -tcgctacacccactagaaaccacggatcgtaatacggcaatcggttttcgataataggtg -gaacgtatattttatttaaggacttaacaattgtctgtaaaccacaatttgcttccgccg -atcctgtattaactatctgtaaaagcatatgttgaccgggaggagccgaacattctccga -tattcaatttttgtatatctataatgttattaacctccgcatacgcattacagttctttt -ctagcttggatactacactaggtacatcatctaaatctattcctatttcctcagcgatag -ctcttctatccttttccgaaagtaatgaaatcacttcaataaatgattcaaccatgagtg -tgaaactaagtcgagaattactcatgcatttgttagttattcggagcgcgcaatttttaa -actgtcctataacctctcctatatgaatagcacaagtgacattagtagggatagaatgtt -gagctaatttttgtaaataactatctataaaaagattatacaaagttttaaactctttag -tttctgccatttatccagtctgagaaaatgtctctcataataaatttttccaagaaacta -attgggtgaagaatggaaacctttaatctatatttatcacagtctgttttggtacacatg -atgaattcttctaatgctgtactaaattcgatatctttttcgatttctggatatgttttt -aataaagtatgaacaaagaaatggaaatcgtaataccagttatgttcaactttgaaattg -ttttttattttcttgttaatgattccagccacttgggaaaagtcaaagtcgtttaatgcc -gatttaatacgttcattaaaaacaaactttttattctttagatgaattattattggttca -ttggaatcaaaaagtaagatattatcgggtttaagatctgcatgtaaaaagttgtcacaa -cagggtagttcgtagattttaatgtataacagagacatctgtaaaaagataaactttatg -tattgtaccaaagatttaaatcctaatttgatagctaactcggtatctactttatctgcc -gaatacagtgctaggggaaaaattataatatttcctctttcgtattcgtaattagttctc -ttttcatgttcgaaaaagtgaaacatgcggttaaaatagtttataacattaatattactg -ttaataactgccggataaaagtgggatagtaatttcacgaatttgatactgtcctttctc -tcgttaaacgcctttagaaaaactttagaagaatatctcaatgagagttcctgaccatcc -atagtttgtatcaataatagcaacatatgaagaacccgcttatacagagtatgtaaaaat -gttaatttatagtttaatcccatggcccacgcacacacgattaattttttttcatctccc -tttagattgttgtatagaaatttgggtactgtaaactccgccgtagtttccatgggacta -tataattttgtggcctcgaatacaaattttactacatagttatctatcttaaagactata -ccatatcctcctgtagatatgtgataaaaatcgtcgtttataggataaaatcgtttatct -ttttgttggaaaaaggatgaattaatgtaatcattctcttctatctttagtagtgtttcc -ttattaaaattcttaaaataatttaacaatctaactgacggagcccaattttggtgtaaa -tctaattgggacattatgttgttaaaatataaacagtctcctaatataacagtatctgat -aatctatggggagacatccattgatattcaggggatgaatcattggcaacacccatttat -tgtacaaaaagccccaatttacaaacgaaagtccaggtttgatagagataaactattaac -tattttgtctctgtttttaacacctccacagtttttaatttctttggtaatgaaattatt -cacaatatcagtatcttctttatctaccagagattttactaacttgataaccttggctgt -ctcattcaatagggtagtgatatttgtatgtatgatattgatatctttttgaattgtttc -ttttagaagtgattctttgatggtatcagcatacgaattacaataatgcagaaactcagt -taacatgcaggaattatagtaagccaattccaattgttgcctgtattgtattagagtatt -aatatgcgcaatgatgtccttgcgtttctctgatagaatgcgagcagcgattttggcgtt -atcatttgacgatatttctggaatgacgaatcctgtttctactaacttcttggtaggaca -aagtgaaacaatcaagaaaatagcttctcctcctatttgtggaagaaattgaactcctct -agatgatctactgacgatagtatctccttgacagatattggaccgaactacggaagtacc -tggaatgtaaagccctgaaaccccctcattttttaagcagattgttgccgtaaatcctgc -actatgcccaagatagagagctcctttggtgaatccatcactatgtttcagtttaaccaa -gaaacagtcagctggtctaaaatttccatctctatctaatacagaatccaacttgatgtc -agggactatgaccggtttaatgttatatgtaacattgagtaaatccttaagttcataatc -atcgttgtcatcagttatgtacgatccaaacaatgtttctaccggcatggtggatacgaa -gatgctatccatcagaatgtttccctgattagtattttctatatagctattcttctttaa -acgattttccgaatcagtaactatgttcatttttttaggagtaggacgtctagccagtat -ggaagaggattttctagatactctcttcaacatctttgatctcaatggaatgcaaaaccc -catggtgtaacaaccaacgataaaaataatattgttttttcactttttataattttacca -tctgactcatggattcattaatatctttacaagagctactaacgtataattctttataac -taaactgagatatatacaccggatctatggtttccataattgagtaaatgaatgctcggc -aataactaatggcaaatgtatagaacaacgaaattatactagagttgttaaagttaatat -tttctatgagttgttccaataaattatttgttgtgactgcgttcaagtcataaattatct -tgatactatccagtaaacagtctttaagttctggaatattatcatcccattgtaaagccc -ctagttcgactatcgaatatcctgctctgatagcagtttcaatatcgacggacgtcaata -ctgtaataaaggtggtagtattgtcatcatcgtgataaactacgggaatatggtcgttag -taggtaccgtgactttacacaacgcgatatataactttccttttgtaccatttttaacgt -agttgggacgtcctgcagggtattgttttgaagaaatgatatcgagaacagatttgatac -gatatttgttggattcctgattattcactataatataatctagacagatagatgattcga -taaatagagaaggtatatcgttggtaggataatacatccccattccagtattctcggata -ctctattgatgacactagttaagaacatgtcttctattctagaaaacgaaaacatcctac -atggactcattaaaacttctaacgctcctgattgtgtttcgaatgcctcgtacaaggatt -tcaaggatgccatagattctttgaccaacgatttagtattgcgtttagcatctgattttt -ttattaaatcaaatggtcggctctctggtttactaccccaatgataacaatagtcttgta -aagataaaccgcaagaaaatttatacacatccatccaaataaccctagcaccgtcggatg -atattaatgtattattatagattttccatccacagttattgggccagtatactgttagca -acggtatatcgaatagattactcatgtaacctactagaatgatagttcgtgtactagtca -taatatctttaatccaatctaagaaatctaaaattagatcttttacactattaaagttaa -caaaggtattacccgggtacgtggatatcatatatggtattggtccattatcagtaatgg -ctccataaactgatacggcaatggtttttatatgtgtttgatctaatgaggacgaaattc -gcgcccacaattcatctctagatatgcatttaatatcgaacggtaacacatcaatctcgg -gacgcgtatatgtttctaaattcttaatccaaatataatgatgacctatatgccctatta -tcatactgtcaactatagtatacctagagaactttcgatacatctgctgtttcctgtaat -cgttaaattttacaaatctataacatgctaaaccttttgacgacagccattcattaattt -ctgatatggaatctgtattcttaataccgtatcgttctaaagccagtgctatatctccct -gttcgtgggaacgctttcgtataatatcgatcaatggataatatgaagtttttggagaat -aatatgattcatgatctatttcgtccataaacaatctagacataggaattggaggcgatg -atcttaattttgtgcaatgggtcaatcctataacttctaatattgtaatattcatcatcg -acataacactatctatgttatcatcgtatattagtataccacgaccttcttcatttcgtg -ccaaaatgatatacagtcttaaataattacgcaatatctcaatagtttcataattgttag -ctgttttcatcaaggtttgtatcctgtttaacatgatggcgttctataacgtctctattt -tctatttttaatttttttaaatttttaacgatttactgtggctagatacccaatctcttt -caaatatttttttagccttgcttacaagctgtttatctatactattaaaactgacgaatc -cgtgattttggtaatgggttccgtcgaaatttgccgaagtgatatgaacatattcgtcgt -cgactattaacaattttgtattattctgaatagtgaaaaccttcacagatagatcatttt -gaacacacaacgcatctagacttctggcggttgccatagaatatacgtcgttcttatccc -aattaccaactagaagtctgatcttaactcctctattaatggctgcttctataatggagt -tgtaaatgtcaggccaatagtagctattaccgtcgacacgtgtagtgggaactatggcca -aatgttcaatatctatactagtcttagccgacttgagtttatcaataactacatcagtgt -ctagatctctagaatatcccaataggtgttctggagaatcagtaaagaacactccaccta -taggattcttaatatgatacgcagtgctaactggcagacaacaagccgcagagcataaat -tcaaccatgaattttttgcgctattaaaggctttaaaagtatcaaatcttctacgaagat -ctgtggccagcggaggataatcagaatatacgcctaacgttttaatcgtatgtatagatc -ctccagtaaatgacgcgtttcctacataacatctttcatcatcagacacccaaaaacaac -cgagtagtagtcccacattattttttttatctatattaacggttataaaatttatatccg -gggagtgactttgtagctctcccagatttcttttccctcgttcatctagcaaaactatta -ttttaatccctttttcagatacctcttttagtttatcaaaaataagcgctcccctagtag -tactcagaggattacaacaaaaagatgctatgtatatatatttcttagctagagtgataa -tttcgttaaaacattcaaatgttgtcaaatgatcggatctaaaatccatattttctggta -gtgtttctaccagcctacattttgctcccgcaggtaccgatgcaaatggccacatttagt -taacataaaaacttatatatcctgttctatcaacgattctagaatatcatcggctatatc -gctaaaattttcatcaaagtcgacatcacaacctaactcagtcaatatattaagaagttc -catgatgtcatcttcgtctatttctatatccgtatccattgtagattgttgaccgattat -cgagtttaaatcattactaatactcaatccttcagaatacaatctgtgtttcattgtaaa -tttataggcggtgtatttaagttggtagattttcaattatgtatcaatatagcaacagta -gttcttgctcctccttgattttagcatcctcttcattattttcttctacgtacataatca -tgtctaatacgttagacaacacaccgacgatggtggccgccacagacacgaatatgacta -gaccgatgaccatttaaaaaatactctctagctttaacttaaactgtatcgatcattctt -ttagcacatgtataatataaaaacattattctatttcgaatttaggcttccaaaaatttt -tcatccgtaaaccgataataatatatatagacttgttaatagtcggaataaatatattaa -tgcttaaactatcatcatctccacgattagagatacaatatttacattctttttgctgtt -tcgaaactttatcaatacacgttaatacaaacccaggaaggagatattgaaactgaggct -gttgaaaatgaaacggcgaatacaataattcagataatgtaaaatcatgattccgtattc -tgatgatattagaactgctaatggatgtcgatggtatgtatctaggagtatctattttaa -caaagcatcgatttgctaatatacaattatccttttgattaattgttattttattcatat -tcttaaaaggtttcatatttatcaattcttctacattaaaaatttccatttttaatttat -ctagccccgcaatactcctcattacgtttcattttttgtctagaatacccattttgttca -tcttggtacatagattatccaattgagaagcgcatttagtagttttgtacattttaagtt -tattaacgaatcgtcgaaaactagttatagttaacattttattatttgataccctgatat -taatacccctgccgttactattatttataactgatgtaacccacgtaacattggaattaa -ttatcgatagtaatgcatcgacacttccaaaattgtctattataaactcaccgataattt -ttttattgcatgttttcatattcattaggattatcaaatctttaatcttattacgattgt -atgcgttgatattacaagacgtcattctaaaagacggaggatttccatcaaatgccagac -aatcacgtacaaagtacatggaaataggttttgttctattacgcatcatagattcatata -aaacacccgtagaaatactaatttgttttactctataaaatactattgcatctatttcat -cgttttgtataacgtctttccaagtgtcaaattccaattttttttcattgatagtaccaa -attcttctatctctttaactacttgcatagataggtaattacagtgatgcctacatgccg -ttttttgaaactgaatagatgcatctagaagcgatgctacactagtcacgatcaccactt -tcatatttagaatatatgtatgtaaaaatatagtagaatttcattttgtttttttctatg -ctataaatgaattctcattttgtatccgcacatactccgttttatatcaataccaaagaa -ggaagatatctggttctaaaagccgttaaagtatgcgatgttagaactgtagaatgcgaa -ggaagtaaagcttcctgcgtactcaaagtagataaaccctcatcacccacgtgtgagaga -agaccttcgtccccgtccagatgcgagagaatgaataaccctggaaaacaagtcccgttt -atgagaacggacatgttacaaaatatgtttgctgctaatcgcgacaacgtaacgtcaaga -cttttgaactaaaatacaattatatctttttcgatattaataaatccgtgtctcccgggt -tttttatctctttcagtatgtgaatagataggtattttatctctattcatcatcgaattt -aagagatccgataaacattgtttgtattctccagatgtcagcatctgatacaacaatata -tgtgcacataaacctctggcacttatttcatgtaccttccccttatcactaaggagaata -gtatttgagaaatatgtatacatgatattatcatgtattagatatacagaatttgtaaca -ctctcgaaatcacacgatgtgtcggcgttaagatctaatatatcactcgataacacattt -tcatctagatacactagacattttttaaagctaaaatagtctttagtagtaacagtaact -atgcgattattttcatcgatgatacatttcatcggcatattattacgcgtaccatcaaag -actataccatgtgtatatctaacgtattctagcatagttgccatacgtacattaaacttt -tcaggatctttggatagatcttccaatctatctatttgagaaaacatttttatcatgttc -aatagttgaaacgtcggatccactatatagatattatctataaagattttaggaactatg -ttcatggtatcctggcgaatattaaaactatcaatgatatgattatcgttttcatctttt -atcaccatatagtttctaagatatgggattttacttaatataatattatttcccgtaata -aattttattagaaatgccaaatctataagaaaagtcctagaattagtctgaagaatatct -atatcaccgtaccgtatatttggattaattagatatagagaatatgatccgtaacatata -caacttttattatgacgtctaagatattcttccatcaacttattaacatttttgactagg -gaagatacattatgacgtcccattacttttgccttgtctattacagcgacgttcatagaa -tttagcatatctcttgccaattcttccattgatgttacattataagaaattttagatgaa -attacatttggagctttaatagtaagaactcctaatatatccgtgtatgtggtcactaat -acagattgtagttctataatcgtaaataatttacctatattatatgtttgagtttgttta -gaaaagtagctaagtatacgatcttttatttctgatgccgatgtatcaacatcgaaaaaa -aatctttttttattcttttttactaacgatacgaatatgtctttgttaaaaacagttatt -ttctgaatatttctagcttgtaattttaacatatgatattcgttcacactaggtactctg -cctaaataggtttctataatctttaatgtaatattaggaagagtattctgatcaggattc -ctattcattttgaggatttaaaactctgattattgtctaatatggtctcaacacaaactt -tttcacagagtgatagagtttttgataactcgtttttcttaagaaatataaaactactgt -ctccagagctcgctctatcttttattttatctaattcgatacaaactcctgatactggtt -cagaaagtaattcattaattttcagtcctttatagaagatatttaatatagataatacaa -aatcttcagttcttgatatcgatctgattgatcctagaactagatatattaataacgtgc -tcattaggcagtttatggcagcttgataattagatatagtatattccagttcatatttat -tagataccgcattgcccagattttgatattctatgaattcctctgaaaataaatccaaaa -taactagacattctattttttgtggattagtgtactctcttccctctatcatgttcacta -ctggtgtccacaatgataaatatctagagggaatataatatagtccatatgatgccaatc -tagcaatgtcgaataactgtaattttattcttcgctcttcattatgaattgaatcttgag -gtataaacctaacacaaattatatcattagacttttcgtatgtaatgtctttcatgttat -aagtttttaatcctggaatagaatctattttaatgaggcttttaaacgcagcgttctcca -acgagtcaaagcataatactctgttggttttcttatattcaatattacgattttcttctt -tgaatggaataggtttttgaattagtttataattacaacataatagataaggaagtgtgt -aaatagtacgcggaaaaaacataatagctcccctgttttcatccatggttttaagtaaat -gatcactggcttctttagtcaatggatattcgaacattaaccgtttcatcatcattggac -agaatccatatttcttaatgtaaagagtgatcaaatcattgtgtttattgtaccatcttg -ttgtaaatgtgtattcggttatcggatctgctcctttttctattaaagtatcgatatcga -tctcgtctaagaattcaactatatcgacatatttcatttgtatacacataaccattacta -acgtagaatgtataggaagagatgtaacgggaacagggtttgttgattcgcaaactattc -taatacataattcttctgttaatacgtcttgcacgtaatctattatagatgccaagatat -ctatataattattttgtaagatgatgttaacaatgtgatctatataagtagtgtaataat -tcatgtatttcgatatatgttccaactctgtctttgtgatgtctagtttcgtaatatcta -tagcgtcctcaaaaaatatattcgcatatattcccaagtcttcagttctatcttctaaaa -aatcttcaacgtatggaatataataatctattttacctcttctgatgtcattaatgatat -agtttttgacactattttccgtcaattgattcttattcactatgtctaaaaaccggatag -cgtccctaggacgaactactgccattaatatctctattatagcttctggacataaatcat -ctattataccagaattaatgggaactattccgtatctatctaacatagttttaagaaagt -cagaatctaagacctgatgttcatatattggttcatacatgaaatgatctctattgatga -tagtgactatttcattctctgaaaattggtaactcattctatacacgctttccttgttga -taaaggatagtatatactcaatggaatttgtaccaacaaactgttctcttatgaatcgta -tatcatcatctgaaatgatcatgtaaggcatacatttaacaataagagacttgtctcctg -ttatcaatatactattcttgtgataatttatgtgtgcggcaaatttgtccacgttcttta -attttgttatagtagatatcaaatccaatggagatacagttcttggcttaaacagatata -gtttttctggaacgaattctacaacattattataaaggactttgggtatataagtgggat -gaaatcctattttaattaatgcgatagccttgtcctcgtgcagatatccaaacgcttttg -tgatagtatggcattcattgtctagaaacgctctacgaatatctgtaacagatatcatct -ttagagaatactagtcgcgttaatagtactaaaatttgtattttttaatctatctcaata -aaaaattaatatgtatgattcaatgtataactaaactactaactgttattgataactaga -atcagaatctaatgatgacataactaagaagtttatctacagccaatttagctgcattat -ttttagcatctcgtttagattttccatctgccttatcgaatactcttccgtcaatgtcta -cacaggcataaaatgtaggagagttactaggccccactgattcaatacgaaaagaccaat -ctctcctagttatttgacagtactcattaataacggtgacagggttaacacctttccaat -aaataatttttttaaccggaataacatcatcaaaagacttatgatcctctctcattgatt -tttcgcgggatacatcatctattatagcatcagcatcagaatctgtaggccgtgtatcag -catccattgtcgtagaccaacgaggaggagtatcgttggagctgtaaaccatagcactac -gttgaagatcatacagagctttattaacttctcgcttctccatattaagttgtttagtta -gttgtacagcagtagctccttagtccaatgtttttaataaccgcacacaatctctgtgtc -agaacgctcgtcaatatagatcttagaaatttttttagagagaactaacgcaactagcaa -taaaactgatcttattttatcattttttttattcatcatcctctggtggttcgtcgttcc -tatcgaatgtagctctgattaacccgtcatctataggtgatgctggttctggagattctg -gaggagatggattattatctggaagaatctctgttatttccttgttttcatgtatcgatt -gcgttgtaacattaagattgcgaaatgctctaaatttgggaggcttaaagtgttgtttac -aatctctacacgcgtgtctaactaatggaggttcatcagcggctctagtttgaatcatca -tcggtgtagtattcctacttttacagttaggacacggtgtattgtatttctcgtcgagaa -cgttaaaataatcgttgtaactcacatcctttattttatctatattgtattctactcctt -tcttaatgcattttataccgaacaagagatagcgaaggaattctttttcggtaccgctag -tacccttaatcatatcacatagtgttttatattctaaatgtgtggcaatggacggtttat -ttctatacgatagtttgtttttggaatcctttgagtattctataccaatattattctttg -attcgaatttagtttcttcgatattagattttgtattacctatattcttgatgtagtact -ttgatgatttttccatggcccattctattaagttttccaagttggcatcatccacatatt -gtgatagtaattctcggatatcagtagtgactaccgccattgatatttgttcatttgatg -agtaactactaatgtatacattttccatttataacacttatgtattaactttgtttattt -atattttttcattattatgttgatattaataatcgtattgtggttatatggctacaattt -cataatgagttgaagtcagtgtcctatgatcaatgacgatagctttactctgaaaagaaa -gtatcaaatcgatagtgcagagtcaacaatgaaaatggataagacgatgacaaagtttca -gaatagagtcaaaatggtaaaagaaataaatcagacgataagagcagcacaaactcatta -cgagacattgaaactaggatatataaaatttaagggaatgattaggactactactctaga -agatatagcaccatctattccaaataatcagaaaacttataaactattctcggacatttc -agtcattggcaaagcatcacagaatccgagtaagatgatatatgctcgctgctttacatg -tttcccaatttgtttggagatgaccatagattcatttgttatagaatgcatccaacattg -ttcatgatatagttgaatcatgtatgcctgttcgtatgcctgtggctaagatactgtgta -aagaaatggtaaataaatactttgagaatctttaagagtgcattgactttgttagtgaat -aggcattccatctttctccaatactaattcaaattgttaaattaataatggaatagtata -aatagttattagtgataggatagtaaacataattattagaatagtagtgtagtatcatag -ataactctcttctataaaaaatggattttattcgtagaaagtatcttatatacacagtag -aaaataatatagattttttaaaggatgatacattaagtaaagtaaacaattttaccctca -atcatgtactagctctcaagtatctagttagcaattttcctcaacatgttattactaagg -atgtattagctaataccaatttttttgttttcatacatatggtacgatgctgtaaagtat -acgaagcggttttacgacacgcatttgatgcacccacgttgtacgttaaagcattgacta -agaattatttatcgtttagtaacacaatacagtcgtacaaggaaacagtgcataaactaa -cacaagatgaaaaatttttagaggttgccgaatacatggacgaattaggagaacttatag -gcgtaaattatgacttagttcttaatccattatttcacggaggggaacccatcaaagata -tggaaatcatttttttaaaactgtttaagaaaacagacttcaaagttgttaaaaaattaa -gtgttataagattacttatttgggcatacctaagcaagaaagatacaggcatagagtttg -cggataatgatagacaagatatatatactctatttcaacaaactggtagaatagtccata -gcaatctaacagaaacgtttagggattatatctttcccggagataagactagctattggg -tgtggttaaacgaaagtatagctaatgatgcggatatcgttattaatagacccgccatta -ccatgtatgataaaattcttagttatatatactctgagataaaacagggacgcgttaata -aaaacatgcttaagttagtttatatctttgagcctgaaaaagatatcagagaacttctgc -tagaaatcatatatgatattcctggagatatcctatctattattgatgcaaaaaacgacg -attggaaaaaatattttattagtttttacaaagctaattttattaacggtaatacattta -ttagtgatagaacgtttaacgatgacttattcagagttgttgttcaaatagatcccgaat -atttcgataatgaacgaattatgtctttattctatacgagtgctgcggacattaaacgat -ttgatgagttagatattaataacagttatatatctaatataatttatgaggtgaacgata -tcacattagatacaatggatgatatgaagaagtgtcaaatctttaacgaggatacgttgt -attatgttaaggaatacaatacatacctgtttttgcacgagtcggatcccatggtcatag -agaacggaatactaaagaaactgtcatctataaaatccaagagtagacggctgaacttgt -ttagcaaaaacattttaaaatattatttagacggacaattggctcgtctaggtcttgtgt -tagatgattataaaggagacttattagttaaaatgataaaccatctcaaatctgtggagg -atgtatccgcattcgttagattttctacagataaaaaccctagtattcttccatcgctaa -tcaaaactattttagctagttataatatttccatcatcgtcttatttcaaaggtttttaa -gagataatctatatcatgtagaagaattcttggataaaagcatccatctaaccaagacgg -ataagaaatatatacttcaattgataaggcacggtagatcatagaacaaaccaaatatat -tattaataatttgtatatacatagatataattatcacatattaaaaaataacacattttt -gataaatggaaaccgttgcaacaattcagactcccaccaaattaatgaataaagaaaatg -cagaaatgattttggaaaaaattgttaatcatatagctatgtatattagtgacgaatcaa -tatattcagaaaataatcctgaatatattgattttcgtaacagatacggagactatagat -ctctcattataaaaagtgatcacgagtttgtaaagctatgtaaagatcatgcagagaaaa -gttctccagaaacgcaacaaatgattatcaaacacatatacgaacaatatcttattccag -tatctgaagtactattaaaacctataatgtccatgggtgacatatttacatataacggat -gtaaagacaatgaatggatgctagaacaactctctaccctaaactttaacaatctctaca -catggaactcatgtagcataggcaatgtaacgcgtctgttttatacattttttagttatc -tgatgaaagataaactaaatatataagtataatcccattctaatactttaacctgatgta -ttattacctgcatcttattagaatattaacctaactaaaagacataaaaagcggtaggat -ataaatattatggccgcaaccgttccgcgttttgacgatgtgtacaaaaatgcacaaaga -agaattctagatcaagaaacattttttagtagaggtctaagtagaccgttaatgaaaaac -acatatctatttgataattacgcgtatggatggataccagaaactgcaatttggagtagt -agatacgcaaacctagatgctagtgactattatcccatttcgttgggattacttaaaaag -tttgaatttctcatgtctctatataaaggtcctattcccgtatatgaagaaaaagtaaat -actgaattcattgctaatggatctttctccggtagatacgtatcatatcttagaaagttt -tctgcccttccaacaaacgagtttattagttttttattattgacctccatccctatctat -aatatcttattctggtttaaaaacacacagtttgatattactaaacacacattattcaga -tacgtctatacagataataccaaacaccttgcgttggctaggtatatacatcaaacagga -gactataagcctttgtttagtcgtctcaaagagaattatatatttactggtcccgttcca -ataggtatcaaagatatagatcaccctaatcttagtagagcaagaagtccatccgattat -gagacattagctaatattagtactatattgtactttaccaagtatgatccagtattaatg -tttttattgttttacgtacctgggtattcaattactacaaaaattactccagccgtagaa -tatctaatggataaactgaatctaacaaagagcgacgtacaactgttgtaaattatttta -tgcttcgtaaaatgtaggtcttgaaccaaacattctttgaaaaaatgagatgcataaaac -tttattatccaatagattaactatttcagacgtcaatcgtttaaagtaaacttcgtaaaa -tattctttgattgctgccgagtttaaaacttctatcgataattgtttcatatgttttaat -atttacaagttttttggtccatggtacattagctggacagatatatgcaaaataatatcg -ttctccaagttctatagtctctggattgtttttattatattcagtaaccaaatacatatt -agggttatctgcggatttataatttgagtgatgcattcgactcaacataaataattctag -aggagacgatctactatcaaattcggatcgtaaatctgtttctaaagaacggagaatatc -tatacatacctgattagaattcatccgtccttcagacaacatctcagacagtctggtctt -gtatgtcttaatcatattcttatgaaacttggaaacatctcttctagtttcactagtacc -tttattaattctctcaggtacagattttgaattcgacgatgccgagtatttcatcgttgt -atatttcttcttcgattgcataatcaaattcttatataccgcctcaaactctattttaaa -attattaaacaatactctactattaatcagtcgttctaactcctttgctatttctatgga -cttatctacatcttgactgtctatctctgtaaacacggagtcggtatctccatacacgct -acgaaaacgaaatctataatctataggcaacgatgttttcacaatcggattaatatctct -atcgtccatataaaatggattacttaatgtattggcaaaccgtaacataccgttggataa -ctctgctccatttagtaccgattctagatacaatatcattctacgtcctatggatgtgca -actcttagccgaagcgtatgagtatagagcactatttctaaatcccatcagaccatatac -tgagttggctactatcttgtacgtatattgcatggaatcatagatggccttttcagttga -actggtagcctgttttaacatctttttatatctggctctctctgccaaaaatgttcttaa -tagtctaggaatggttccttctattgatctatcgaaaattgctatttcagagatgaggtt -cggtagtctaggttcacaatgaaccgtaatatatctaggaggtggatatttctgaagcaa -gagttgattatttatttcttcttccaatctattggtactaacaacgacaccgactaatgt -ttccggagatagatttccaaagatacacacattaggatacagactgttataatcaaagat -taatacattattactaaacattttttgttttggagcaaataccttaccgccttcataagg -aaacttttgttttgtttctgatctaactaagatagttttagtttccaacaatagctttaa -cagtggacccttgatgattgtactcgctctatattcgaataccatggattgaggaagcac -atatgttgccgcaccagcgtctgtttttgtttctactccataatactcccacaaatactg -acacaaacaagcatcatgaatacagtatctagccatatctaaagctatgtttagattata -atccttatacatctgagctaaatcaatgtcatcctttccgaaagataatttatatatatc -attaggtaaagtaggacatgatagtacgactttaaatccattttccaaaatatctttacg -aattactttacatataatatcctcatcaacagtcacgtaattacctgtggttaaaacctt -tgcaaatgtatcggctttgcctttcgcgtccgtagtatcgtcaccgatgaacgtcatttc -tctaactcctctatttaatactttacccatgcaactgaacgcgttcttggatatagaatc -caatttgtacgaatccaatttttcagatttttgaatgaatgaatatagatcgaaaaatat -agttccattattgttattaacgtgaaacgtagtattggccatgccgcatactcccttatg -actagactgatttctctcataaatacagagatgtacagcttcctttttgtctggagatct -aaagataatcttctctcctgttaataactctagacgattagtaatatatctcagatcaaa -gttatgtccgttaaaggtaacgacgtagtcgaacgttagttccaacaattgtttagctat -tcgtaacaaaactatttcagaacatagaactagttctcgttcgtaatccatttccattag -cgactgtatcctcaaacatcctctatcgacggcttcttgtatttcctgttccgttaacat -ctcttcattaatgagcgtaaacagtaatcgtttaccacttaaatcgatataacagtaact -tgtatgcgagattgggttaataaatacagaaggaaacttcttatcgaagtgacactctat -atctagaaataagtacgatcttgggatatcgaatctaggtatttctttagcgaaacagtt -acgtggatcgtcacaatgataacatccattgttaatctttgtcaaatattgctcgtccaa -cgagtaacatccgtctggagatatcccgttagaaatataaaaccaactaatattgaaaaa -ttcatccatggtggcattttgtatgctgcgtttctttggctcttctatcaaccacatatc -tgcgacggagcattttctatctttaatatctagattataacttattgtctcgtcaatgtc -tatagttctcatctttcccatcggcctcgcattaaatggaggaggagataatgactgata -tatttcgtccgtcactacgtaataaaagtaatgaggaaatcgtataaatacggtctcgcc -atttcgacatctggatttcagatataaaaatctgttttcaccgtgactttcaaaccaatt -aatacacctaacatccatttctagaatttagaaatatattttcatttaaatgaatcccaa -acattggggaagagccgtatggaccattatttttatagtactttcgcaagcgggtttaga -cggcaacatagaagcgtgtaaacgaaaactatatactatagtcagcactcttccatgtcc -tgcatgtagacgacacgcgactatcgctatagagaacaataatgtcatgtctagcgatga -tctgaattatatttattattttttcatcagattatttaacaatttggcatttgatcccaa -atacgcaatcgatgtgtcaaaggttaaacctttataaacttaacccattataaaacttat -gattagtcacgactgaaataaccgcgtgattattttttggtataattctacacggcatgg -tttctgtgactatgaattcaacacctgttatcttagtgaaatctttaacaaacagcaagg -gttcgtcaaagacataaaactcattgtttacgatcgaaatagaccccctatcacacttaa -aataaaaaatatccttatcctttaccaccaaataaaattctgattggtcaatgtgaatgt -attcacttaacagttccacaaatttatttattaactccgaggcacatacatcgtcggtat -tttttatgacaaactttactcttccagcatccgtttctaaaaaaatattaacgagttcca -tttatatcatccaatattattgaaatgacgttgatggacagatgatataaataagaaggt -acagtacctttgtccaccatctcctccaattcatactctattttgtcattaactttaatg -tgtgaaaacagtacgccacatgcttccatgacagtgtgtaacactttggatacaaaatgt -ttgacattagtataattgtccaagactgtcaatctataatagatagtagctataatatat -tctatgatggtattgaagaagatgacaaccttggcatattgatcatttaacacagacatg -gtatcaacaaatagcttaaatgaaagagaatcagtaattggaataagcgtcttctcgatg -tagtgtccgtataccaacatgtctgatattttgatgtattccattaaattatttagtttt -ttctttttattctcgttaaacagaatttctgtcaatggaccccaacatcgttgacctatt -aagttttgattgatttttccgtgtaaggcgtatctagtcagatcgtatagcctatccaat -aatccatcgtctgtgcgtagatcacatcgtacactttttaattttctatagaagagtgac -agacatctggagcaattacagacagcaatttctttattctctacagatgtaagatacttg -aagatattcctatgatgatgcagaattttggataacacggtattgatggtatctgttacc -ataattcctttgactgatagtgtcaaagtacaagatttccaatcttttgcaattttcagt -accattatctttgttttgatatctatatcagacagcatggtacgtctgacaacacaggga -ttaagacggaaagatgaaatgattctctcaacatcttcaatagataccttgctatttttt -ttggcattatctatatgtgagagaatatcctctagagaatcagtatcctttttgatgata -gtggatctcaatgacatgggacgtctaaaccttcttattctatcaccagattgcatggtg -atttgtcttctttcttttatcatgatgtaatctctaaattcatcggcaaattgtctatat -ctaaaatcataatatgagatgtttacctctacaaatatctgttcgtccaatgttagagta -tctatatcagttttgtattccaaattaaacatggcaacggatttaattttatattcctct -attaagtcctcgtcgataataacagaatgtagataatcatttaatccatcgtacatggtt -ggaagatgctcgttgacaaaatctttaattgtcttgatgaaggtgggactatatctaaca -tcttgattaataaaatttataacattgtccataggatactttgtaactagttttatacac -atctcttcattggtaagtttagacagaatatcgtgaacaggtggtatattatattcatca -gatatacgaagaataatgtccaaatctatattgtttaatatattatatagatgtagtgta -gctcctacaggaatatctttaactaagtcaatgatttcatcaacagttagatctatttta -aagttaatcatataggcattgatttttaaaaggtatgtagccttgactacattctcatta -attaaccattccaagtcactgtgtgtaagaagattatattctatcataagcttgactaca -tttggtcccgataccattaaagaattcttatgatataaggaaacagcttttaggtactca -tctactctacaagaattttggagagccttaacgatatcagtgacgtttattatttcagga -ggaaagaacctaacattgagaatatctgaattaatagcttccagatacagtgattttggc -aatagtccgtgtaatccataatccagtaacacgagctggtgcttgctagacaccttttca -atgtttaatttttttgaaataagctttgataaagccttcctcgcaaattccggatacatg -aacatgtcgccaacatgattaagtattgtttttcattatttttatattttctcaacaagt -tctcaataccccaatagataatagaatatcacccaatgcgtccatgttgtctatttccaa -caggtcgctatatccaccaatagaagttttcccaaaaaagattctaggaacagttctacc -accagtaatttgttcaaaatagtcacgcaattcattttcgggtttaaattctttaatatc -tacaatttcatacgctcctcttttgaaactaaacttatttagaatatccagtgcgtttct -acaaaaaggacatgtaaacttgacaaaaattgtcactttgttattggccaacctttgttg -tacaaattcctcggccatttttaatatttaagtgatacaaaactatctcgacttatttaa -ctctttagtcgagatatatggacacagatagctatatgataaccaactacagaagacaaa -cgctataaaaaacataattacgacgagcatatttataaatatttttattcagtattactt -gatatagtaatattaggcacagtcaaacattcaaccactctagatacattaactctctca -ttttctttaacaaattctgcaatatcttcgtaaaaagattcttgaaactttttagaatat -ctatcgactctagatgaaatagcgttcgtcaacatactatgttttgtatacataaaggcg -cccattttaacagtttctagtgacaaaatgctagcgatcctaggatcctttagaatcaca -tagattgacgattcgtctctcttagtaactctagtaaaataatcatacaatctagtacgc -gaaataatattatccttgacttgaggagatctaaacaatctagttttgagaacatcgata -agttcatcgggaattacatacatactatctttaatagaactcttttcatccagttgaatg -gattcgtccttaaccaactgattaatgagatcttctattttatcattttctagatgatat -gtatgtccattaaagttaaattgtgtagcgcttctttttagcctagcagccaatacttta -acatcactaatatcgatatacaaaggagatgatttatcgatggtattaagaattcgtttt -tcgacatccgtcaaaaccaattcctttttgcctgtatcatccagtttgccattctttgta -aagaaattattttctactagactattaataagactgataaggattcctccataattgcac -aatccaaactttttcacaaaactagactttacgagatctacaggaatgcgtacttcaggt -ttcttagcttgtgattttttcttttgtggacattttctagtgaccaactcatctaccatt -tcattgattttagcagtgaaataagctttcaatgcacgggcactgatactattgaaaacg -agttgatcttcaaattccgccatttaagttcaccaaacaacttttaaatacaaatatatc -aatagtagtagaataagaactataaaaaaaataataattaaccaataccaaccccaacaa -cctgtattattagttgatgtgacagttttctcatcacttagaacagatttaacaatttct -ataaagtctgtcaaatcatcttcctgagaacccataaatacaccaaatatagcagcgtac -aacttatccatttatacattgaatattggcttttctttatcgctatcttcatcatattca -tcatcaatatcaacaagtcccagattacgaaccagatcttcttctacattttcagtcatt -gatacgcgttcactatctccagagagtccgataacgttagccactacttctctatcaatg -attagtttcttgagcgcgaatgtaatttttgtttccgttccggatctatagaaaactaca -ggtgtaataattgccttggctaattgtctttctcttttactgagtgattctagttcacct -tctatagatctgagaatggatgattctccagtcgaaacatattctaccatggctccgttt -aatttgttgatgaagatggattcatccttaaatgttttctctgtaatagtttccgccgaa -agactatgcaaagaatttggaatgcgttccttgtgtgtaatgtttccatagacagcttct -agaagttgatacaacataggactagccgcggtaacttttatttttagaaagtatccatcg -cttctatcttgtttagatttatttttataaagtttagtctctccttccaacataataaaa -gtggaagtcatctgactagataaactatcagtaagttttatagagatagatgaacaatta -gcgtattgagaagcatttagtgtaacgcattcgatacattttgcattagatttactaatc -gattttgcatactctataacacccgcacaagtctgtagagaatcgctagatgctgtaggt -cttggtgaagtttcaactctcttcttgattaccttactcatgattaaacctaaataattg -tactttgtaatataatgatatatattttcactttatctcatttgagaataaaaatgtttt -tgttaaccactgcatgatgtacagatttcggaatcgcaaaccacttgtggttttatttta -tccttgtccaatgtgaattgaatgggagcggatgcgggtttcgtacgtagatagtacatt -cccgtttttagaccgagactccatccgtaaaaatgcatactcgttagtttggaataactc -ggatctgctatatggatattcatagattgactttgatcgatgaaggctcccctgtctgca -gccatttttatgatcgtcttttgtggaatttcccaaatagttttataaactcgcttaata -tcttctggaaggtttgtattctgaatggatccaccatctaccataatcctattcttgatc -tcatcattccataattttctctcggttaaaactctaaggagatgcgggttaactacttgg -aattctccagacaatactctccgagtgtaaatattactggtatacggttccaccgactca -ttatttcccaaaatttgagcagttgatgcagtcggcataggtgccaccaataaactattt -ctaagaccgtatgttctgattttatcttttagaggttcccaattccaaagatccgacggt -acaacattccaaagatcatattgtagaataccgttactggcgtacgatcctacatatgta -tcatatggtccttccttctcagctagtttacaactcgcctctaatgcaccgtaataaatg -gtttcaaagatcttcttatttagatcttgtgcttccaggctatcaaatggataatttaag -agaataaacgcgtccgctaatccttgaacaccaataccgataggtctatgtctcttatta -gagatttcagcttctggaataggataataattaatatctataattttattgagatttctg -acaattactttgaccacatccttcagtttgagaaaatcaaatcgcccatctattacaaac -atgttcaatgcaacagatgccagattacacacggctacctcattagcatccgcatattgt -attatctcagtgcaaagattactacacttgatggttcctaaattttgttgattactcttt -ttgttacacgcatccttataaagaatgaatggagtaccagtttcaatctgagattctata -atcgctttccagacgactcgagcctttattatacatttgtatctcctttctctttcgtat -agtgtatacaatcgttcgaactcgtctccccaaacattgtccaatccaggacattcatcc -ggacacatcaacgaccactctccgtcatccttcactcgtttcataaagagatcaggaatc -caaagagctataaatagatctcttgttctatgttcatcgtttcctgtattctttttaaga -tcgaggaacgccataatatcagaatgccacggttccaagtatatggccataactccaggc -cgtttgtttcctccctgatctatgtatctagcggtgttattataaactctcaacattgga -ataataccgtttgatataccattggtaccggagatatagcttccactggcacgaatatta -ctaattgatagacctattccccctgccattttagagattaatgcgcatcgttttaacgtg -tcatagatgccttctatgctatcatcgatcatgttaagtagaaaacagctagacatttgg -tgacgagtagttcccgcattaaataaggtaggagaagcgtgcgtaaaccatttttcagaa -agtagattgtacgtctcaatagctgagtctatatcccattgatgaattcctactgcgaca -cgcattaacatgtgctgaggtctttcaacaattttgttgtttattttcaacaagtaggat -ttttccaaagttttaaaaccaaaatagttgtatgaaaagtctcgttcgtaaataataacc -gaattgagcttatccttatatttgttaactatatccatggtaatacttgaaataatcgga -gaatgtttcccatttttaggattaacatagttgaataaatcctccatcacttcactaaat -agtttttttgtttccttgtgtagatttgatatggctattctggcggctagaatggcataa -tccggatgttgtgtagtacaagtggctgctatttcggctgccagagtgtccaattctacc -gttgttactccattatatattccttgaataaccttcatagctattttaataggatctata -tgatcagtgtttaagccatagcacaattttctaatacgagacgtgattttatcaaacatg -acattttccttgtatccatttcgtttaatgacaaacatttttgttggtgtaataaaaaaa -attatttaatttttcattaatagggatttgacgtatgtagcgtacaaaattatcgttcct -ggtatatagataaagagtcctatatatttgaaaatcgttacggttcgattaaactttaat -gattgcattgtgaatatatcattaggatttaactccttgactatcatggcggtgccagaa -attaccatcaaaagcattaatacagttatgcagatcgcagttagaacggttatagcatcc -accatttatatctaaaaattagatcaaagaatatgtgacaacgtcctagttgtatactga -gaattgacgaaacaatgtttcttacatatttttttcttattagtaaccgacttaatagta -ggaactggaaaactagacttgattattctataagtatagatacccttccaaataatgttc -tctttgataaaagttccagaaaatgtagaattttttaaaaagttatcttttgctattact -aatatcgtggttagacgcttattattaatatgagtgatgaaatccacaccgcttctagat -atcgcttttatttccacattagatggtaaatccaatagtgaaactatctttttaggaatg -tatggactcgcgtttagaggagtgaacgtcttcggagtagtaaaggatgattcgtcaaat -gaataaacaatttcacaaatggatgttaatgtattagtaggaaattttttgacgctagtg -gaattgaagattctaatggatgatgttctacctatttcatccgataacatgttaatttcc -aataccaacggttttaatatttcgatgatatacggtagtctctctttcggacttatatag -cttattccacaatacgagtcattatatactccaaaaaacaaaataactagtataaaatct -gtatcgaatgggaaaaacgaaattatcgatataggtatagaatccggaacattgaacgta -ttaatacttaattctttttcagtggtaagaaccgataggttattgacattgtatggtttt -aaatattctataacttgagacttgatagatattaatgacgaattgaaaattatttttatc -accacgtgtgtttcaggatcatcgtcgacgccagttaaccaaccgaatggagtaaaataa -atatcattaatatatgctctagatattagtatttttattaatcctttgattatcatcttc -tcgtacgcgaatgattccatgatcaagagtgatttgagaacatcctccggagtattaatg -ggtttagtaaacagtccatcgttgcaataataaaagttgtccaagttaaaggatattatg -cattcgtttaaagatatcacctcatctaacggagacaattttttggtaggttttagagac -tttgaagctacttgtttaacaaagttattcatcgtcgtctactattctatttaattttgt -agttaatttatcacatatcacattaattgactttttggtccacttttccatacgtttata -ttcttttaatcctgcgttatccgtttccgttatatacagggatagatcttgcaagttaaa -tagaatgctcttaaataatgtcatttttttatccgctaaaaatttaaagaatgtataaac -ttttttcaaagatttaaaacttttaggtggagttctggtacacaatatcataaacaaact -aataaacatcccacattcagattccaacaattgattaacttccacattaatacagcctat -tttcgctccaaatgtacattcgaaaaatctgaataaaacatcaatatcgcaatttgtatt -atccaatacagaatgtctgtgattcgtgttaaaaccatcggaaaaagaatagaaataaaa -attattataatggtggaattcagttggaatattgcctccggagtcataaaaggatactaa -acattgttttttatcgtaaattacacatttccaatgagacaaataacaaaatccaaacat -tacaaatctagaggtagaacttttaattttgtctttaagtatatacgataagatatgttt -attcataaacgcgtcaaatttttcatgaatagctaaggagtttaagaatctcatgtcaaa -ttgtcctatataatccacttcggatccataagcaaactgagagactaagttcttaatact -tcgattgctcatccaggctcctctctcaggctctattttcatcttgacgacctttggatt -ttcaccagtatgtattcctttacgtgataaatcatcaattttcaaatccatttgtgagaa -gtctatcgccttagatactttttcccgtagttgaggtttaaagaaatacgctaacggtat -actagtaggtaactcaaagacatcatatatagaatggtaacgcgtcgttaactcgtcggt -taactctttcttttgatcgagttcatcgctactattgggtctgctcaggtgccccgactc -tactagttccaacatcataccgataggaatacaagacactttgccagcggttgtagattt -atcatatttctccaccacatatccgttacaatttgttaagaatttagatacatctatatt -gctacataatccagctagtgaatatatatgacataataaattggtaaatcctagttctgg -tattttactaattactaaatctgtatatctttccatttatcatggaaaagaatttaccag -atatcttcttttttccaaactgcgttaatgtattctcttacaaatattcacaagatgaat -tcagtaatatgagtaaaacggaacgtgataatttctcattggctgtgtttccagtgataa -aacatagatggcataacgcacacgttgtaaaacataaaggaatatacaaagttagtacag -aagcacgtggaaaaaaagtatctcctccatcactaggaaaacccgcacatataaacctaa -tgtcgaagcaatatatatatagtgagtatgcaataagctttgaatgttatagttttctaa -aatgtataacaaatacagaaatcaattcgttcgatgagtatatattaagaggactattag -aagctggtaatagtttacagatattttccaattccgtaggtaaacgaatagatactatag -gtgtactagggaataagtatccatttagcaaaattccattggcctcattaactcctaaag -cacaacgagagatatttttagcgtggatttctcatagacctgtagttttaactggaggaa -ccggagtgggtaagacgtcacaggtacccaagttattgctttggtttaattatttatttg -gtggattctcttctctagataaaatcactgactttcacgaaagaccagtcattctatctc -ttcctaggatagctttagttagattgcatagcaataccattttaaaatcattgggattta -aggtactagatggatctcctatctctttacggtacggatctataccggaagaattaataa -acaaacaaccaaaaaaatatggaattgtattttctacccataagttatctctaacaaaac -tatttagttatggcactattattatagacgaagttcatgagcatgatcaaataggagata -ttattatagcagtagcgagaaaacatcatacgaaaatagattctatgtttttaatgactg -ccacgttagaggatgacagggaacgtctaaaaatatttttacctaatcccgcatttatac -atattcctggagatacactgtttaaaattagcgaggtatttattcataataagataaatc -catcttccagaatggcatatatagaagaagaaaagagaaatttagttactgctatacaga -tgtatactcctcctgatggatcatccggtatagtctttgtggcatccgttgcacagtgtc -acgaatataaatcatatttagaaaaaagattaccgtatgatatgtatattattcatggta -aggtcttagatatagacgaaatattagaaaaagtgtattcatcacctaatgtatcgataa -ttatttctactccttatttggaatccagcgttactatacgcaatgttacacacatttatg -atatgggtagagtttttgtccccgctccttttggaggatcacaacaatttatttctaaat -ctatgagagatcaacgaaaaggaagagtaggaagagttaatcctggaacatacgtatatt -tctatgatctgtcttatatgaaatctatacagcgaatagattcagaatttctacataatt -atatattgtacgctaataagtttaatctaacactccccgaagatttgtttataatcccta -caaatttggatattctatggcgtacaaaggaatatatagactcgttcgatattagtacag -aaacatggaataaattattatccaattattatatgaagatgatagagtatgctaaacttt -atgtactaagtcctattctcgctgaggagttggataactttgagaggacgggagaattaa -ctagtattgtacaagaagccattttatctctaaatttacaaattaagattttaaaattta -aacataaagatgatgatacgtatatacacttttgtagaatattattcggtgtctataacg -gaacaaacgctactatatattatcatagacctctaacgggatatatgaatatgatttcag -atactatatttgttcctgtagataataactaaaaatcaaaatctaatgaccacatctttt -tttagagatgaaaaattttccacatctccttttgtagacacgactaaacattttgcagaa -aaaagtttattattatttagataatcgtatacttcatcagtgtagatagtaaatgtgaac -agataaaaggtattcttgctcaatagattggtaaattccatagaatatattaatcctttc -ttcttgagatcccacatcatttcaaccaaagacgttttatccaatgatttacctcgtact -ataccacatacaaaactagattttgcagtgatgtcgtacctggtattcctaccaaacaaa -attttacttttagttcttttagaaaattctaaggtagaatctctatttgtcaatatgtca -tctatggaattaccactagcaaaaaatgatagaaatatatattgatacatcgcagctggt -tttgatctactatactttaaaaacgaatcagattccataattgcttgtatatcatcagct -gaaaaactatgttttacacgtattccttcggcatttctttttaatgatatatcttgttta -gacaatgataaagttatcatgtccatgagagacgcgtctccgtatcgtataaatatttca -ttagatgttagacgcttcattaggggtatacttctataaggtttcttaattagtccatca -ttggttgcgtcaagaactactatctgatgttgttgggtatctctagtgttacacatggcc -ttactaaagtttgggtaaataactatgatatctctattaattatagatgtatatatttca -ttcgtcaaggatattaatatcgacttactatcgtcattaatacgtgtaatgtaatcatat -aaatcatgcgatagccaaggaaaattcaaatagatgttcatcatataatcgtcgctataa -ttcatattaatactttgacattgactaatttgtaatatagcctcgccacgaagaaagctc -tcgtattcagtttcatcgataaaggataccgttaaatataactggttgccgatagtctca -tagtctattaagtggtaagtttcgtataaatacagaatccctaaaatattatctaatgtg -ggattaatccttaccataactgtataaaatggagccggagtcataactattttaccgttt -gtacttactggaatagatgaaggaataatctccggacatgatggtaaagacccaaatgtc -tgtttgaagaaatccaatgttccaggtcctaatctcttgacaaaaattacgatattcgat -cccgatatcctttgcattctatttaccagcatatcacgaactatattaagattatctatc -atgtctattctcccaccgttatataaatcgcctccgctaagaaacgttagtatatccata -caatggaatacttcatttctaaaatagtattcgttttctaattctttaatgtgaaatcgt -atactagaaagggaaaaattatctttgagttttccattagaaaagaaccacgaaactaat -gttctgattgcgtctgactccgtcgctgaattaatagatttacaccaaaaactcatataa -cttctagatgtagaagcattcgctaaaaaattagtagaatcaaaggatataagtagatgt -tccaacaagtgagcaattcccaagatttcatctatatcattctcgaatccgaaattagaa -attcccaagtagatatcctttttcatccgatcattgatgaaaatacgaactttattcggt -aagacgatcatttactaaggagtaaaataggaagtaacgttcgtatatcgttatcgtcgt -ataaattaaaggtgtgttttttgccattaagagacattataattttaccaatattggaat -tataatataggtgtatttgagcactagaaacggtcgatgcatcggtaaatatagctgtat -ctaatgttctagtcggtatttcttcatttcgctgtctaatgatagcgttttctctatctg -tttccattacagctgcctgaagtttattggtcggataatatgtaaaataataagaaatac -atacgaataacaaaaataaaataagatataataaagatgccatttagagatctaattttg -ttcaacttgtccaaattcctacttacagaagatgaggaatcgttggagatagtatcttcc -ttatgtagaggatttgaaatatcttacgatgacttaatatcgtactttccagataggaaa -taccataaatatatttctaaggtatttgaacatgtagatttatcggaggaattaagtatg -gaattccatgatacaactctgagagatttagtatatcttagattgtacaagtattccaag -tatatacggccgtgttataaattaggagataatctaaaaggtatagttgttataaaggac -agaaatatatatattagagaagcaaatgatgacttgatagaatatctcctcaaggaatac -actcctcagatttatacatattctaatgagcgagttcccatagctggttcaaaattaatt -ctttgtggattttctcaagttacatttatggcgtatacaacgtcgcatataacaacaaat -aaaaaggtagatgttctcgtttccaaaaaatgtatagatgaactagtcgatccaataaat -tatcaaatacttcaaaatttatttgataaaggaagcggaacaataaacaaaatactcagg -aagatattttattcggtaacaggtggccaaactccataggtagctttttctatttcggat -tttagaatttccaaattcaccagcgatttatcggttttggtgaaatccaaggatttatta -atgtccacaaatgccatttgttttgtctgtggattgtatttgaaaatggaaacgatgtag -ttagatagatgcgcggcgaagtttcctattagggttccgcgcttcacgtcacccaacata -cttgaatcaccatcctttaaaaaaaatgataagatatcaacatggagtatatcatactcg -gattttaattcttctactgcctcactgacattttcacaaatactacaatacggtttaccg -aaaataatcagtacgttcttcatttatgggtatcaaaaacttaaaatcgttactgctgga -aaataaatcactgacgatattagatgataatttatacaaagtatacaatggaatatttgt -ggatacaatgagtatttatatagccgtcgccaattgtgtcagaaacttagaagagttaac -tacggtattcataaaatacgtaaacggatgggtaaaaaagggaggacatgtaaccctttt -tatcgatagaggaagtataaaaattaaacaagacgttagagacaagagacgtaaatattc -taaattaaccaaggacagaaaaatgttagaattagaaaagtgtacatccgaaatacaaaa -tgttaccggatttatggaagaagaaataaaggcagaaatgcaattaaaaatcgataaact -cacatttcaaatatatttatctgattatgataacataaaaatatcattgaatgagatact -aacacatttcaacaataatgagaatgttacattattttattgtgatgaacgagacgcaga -attcgttatgtgtctagaggctaaaacacagttctctaccacaggagaatggccgttaat -aataagtaccgatcaggatactatgctattcgcgtctgctgataatcatcctaagatgat -aaaaaacttaactcaactgtttaaatttgttccctcggcagaggataactatttagcaaa -attaactgcattagtgaatggatgtgatttctttcctggactctatggggcatctataac -acccaacaacttaaacaaaatacaattgtttagtgattttacaatcgataatatagtcac -tagtttggcaattaaaaattattatagaaagactaactctaccgtagacgtgcgtaatat -tgttacgtttataaacgattacgctaatttagacgatgtctactcgtatattcctccttg -tcaatgcactgttcaagaatttatattctccgcattagatgaaaaatggaatgaatttaa -atcatcttatttagagagcgtgccgttaccctgccaattaatgtacgcattagaaccacg -taaggagattgatgtttcagaagttaaaactttatcatcttatatagatttcgaaaatac -taaatcagatatcgatgttataaaatctatatcctcgatttttggatattctaacgaaaa -ctgtaacaccatagtgttcggcatctataaggataatttactactgagtataaataattc -attttactttaacgatagtctgttaataaccaatactaaaagtgataatataataaatat -aggttactagattaaaaaatggtgttccagctcgtgtgttctacatgcggcaaagatatt -tctcacgaacgatataaattgattatacgaaaaaaatcattaaaggatgtactagtcagt -gtaaagaacgaatgttgtaggttaaaattatctacacaaatagaacctcaacgtaactta -acagtgcaacctctattggatataaactaatggatccggttaattttatcaagacatatg -cgcctagaggttctattatttttattaattatgccatgtcattaactagtcatttgaatc -catcgatagaaaaacatgtgggtatttattatggtacgttattatcggaacacttggtag -ttgaatctacctatagaaaaggagttagaatagtcccattggatagattttttgaaggat -atcttagtgcaaaagtatacatgttagagaatattcaagttatgaaaatagcagctgata -tgtcgttaactttactaggtattccatatggatttggtcatgatagaatgtattgtttta -aattggtagctgaatgttataaaaatgccggtattgatacatcgtctaaacgaatattag -gtaaagatatttttctgagccaaaactttacagatgataatagatggataaagatatatg -attctaataatttaacattttggcaaattgattaccttaaagggtgagttaatatgcata -actactcctccgttgttttttccctcgttctttttcttaacgttgtttgccatcactctc -ataatgtaaagatattctaaaatggtaaacttttgcatatcggatgcagaaattggtata -aatgttgtaattgtattatttcccgtcaatggactagtcacagctccatcagttttatat -cctttagagtatttctcactcgtgtctagcattctagagcattccatgatctgtttatcg -ttgatattggccggaaagatagattttttattttttattatattactattggcaattgta -gatataacttctggtaaatatttttctaccttttcaatctcttctattttcaagccggct -atatattctgctatattgttactagtatcaataccttttctggctaagaagtcatatgtg -gtattcactatatcagttttaactggtagttccattagcctttccacttctgcagaataa -ttagaaattggttctttaccagaaaatccagctactataataggctcaccgatgatcatt -ggcaaaatcctatattgtaccagattaatgagagcatatttcatttccaataattctgct -agttcttgagacattgatttatttgatgaatctatttggttctctagatactctaccatt -tctgccgcatacaataacttgttagataaaatcagggttatcaaagtgtttagtgtggct -agaatagtgggcttgcacgtattaaagaatgctgtagtatgagtaaaccgttttaacgaa -ttatatagtctccagaaatctgtggcgttgcatacatgaactgaatgacatcgaagattg -tccaatatttttaatagctgctctttgtccattatttctatatttgactcgcaacaattg -tagataccattaatcactgattcctttttcgatgccggacaatagcacaattgtttagct -ttggactctatgtattcagaattaatagatatatctctcaatacagattgcactatacat -tttgaaactatgtcaaaaattgtagaacgacgctgttctgtagccatttaactttaaata -atttacaaaaatttaaaatgagcatccgtataaaaatcgataaattgcgccaaattgtgg -catatttttcagagttcagcgaagaagtgtctataaatgtagacttgacggatgaattaa -tgtatatttttgccgccttgggcggatctgtaaacatttgggccattatacctctcagtg -catcagtgttctaccgcggagccgaaaatattgtgtttaaccttccagtgtccaaggtaa -aatcgtgtttgtgtagttttcacaatgatgctatcataaatatagaacctgatctggaaa -ataatctagtaaaactttctagttatcatgtagtaagtgtcgattgtaacaaggaactga -tgcctattaggacagatactactatttgtctaagtatagatcaaaagaaatcttacgtat -ttaattttcacaagtatgaagaaaaatgttgtggtagaaccgtcattcatctagaatggt -tgttgggctttatcaagtgtattagtcagcatcagcatttggctattatgtttaaagatg -acaatattattatgaagactcctggtaatactgatgcgttttccagggaatattctatga -ctgaatgttctcaagaactacaaaagttttctttcaaaatagctatctcgtctctcaaca -aactacgaggattcaaaaagagagtcaatgtttttgaaactagaatcgtaatggataatg -acgataacattctaggaatgttgttttcggatagagttcaatcctttaagattaacatct -ttatggcgtttttagactaatactttcaatgagataaatatgggtggcggagtaagtgtt -gagctccctaaacgggatccacctccgggagtacccactgatgagatgttattaaacgtg -gataaaatgcatgacgtgatagctcccgctaagcttttagaatatgtgcatataggacca -ctaacaaaagataaagaggataaagtaaagaaaagatatccagagtttagattagtcaac -acaggacccggtggtctttcggcattattaagacaatcatataatggaaccgcacccaat -tgctgtcgcacttttaatcgtactcattattggaagaaggatggaaagatatcagataag -tatgaagagggtgcagtattagaatcgtgttggcccgacgtccacgacactggaaaatgc -gatgttgatttattcgactggtgtcagggggatacgttcgatataaacatatgccatcag -tggatcggttcagcctttaataggagtgatagaactgtagagggtcgacaatcgttaata -aatctgtataataagatgcaaagattatgtagtaaagatgctagtgtaccaatatgtgaa -ttatttttgcatcatttacgcgcacacaatacagaagatagtaaagagatgatcgattat -attctaagacaacagtcggcggactttaaacagaaatatatgagatgtagttatcccact -agagataagttagaagagtcattaaaatatgcggaacctcgagaatgttgggatccagag -tgttcgaatgccaatgttaatttcttactaacacgtaattataataatttaggactttgc -aatattgtacgatgtaatacgagcgtgaataacttacagatggataaaacttcctcatta -agattatcatgtggattaagcaatagtgatagattttctactgttcccgtcaatagagca -aaagtagttcaacataatattaaacattcgttcgacctaaaattgcatttgatcagttta -ttatctctcttggtaatatggatactaattgtagctatttaaatgggtgccgcagcaagc -atacagacgactgtgaatacactcagtgaacgtatctcgtctaaattagaacaagaagcg -aacgctagtgctcaaacaaaatgtgatatagaaatcggaaatttttatatccgacaaaac -catggatgtaacatcactgttaaaaatatgtgctctgcggacgcggatgctcagttggat -gctgtgttatcagccgctacagaaacatatagtggattaacaccggaacaaaaagcatac -gtaccagctatgtttactgctgcgttaaacattcagacgagtgtaaacactgttgttaga -gattttgaaaattatgtgaaacagacttgtaattctagcgctgttgtcgataacaaatta -aagatacaaaacgtaattatagatgaatgttacggagccccaggatctccaacaaatttg -gaatttattaatacaggatctagcaaaggaaattgtgccattaaggcgttgatgcaattg -actactaaggccactactcaaatagcacctagacaagttgctggtacaggagttcagttt -tatatgattgttatcggtgttataatattggcagcgttgtttatgtactatgccaagcgt -atgctgttcacatccaccaatgataaaatcaaacttattttagccaataaggaaaacgtc -cattggactacttacatggacacattctttagaacttctccgatgattattgctaccacg -gatatacaaaactgaaaatatattgataatattttaatagattaacatggaagttatcgc -tgatcgtctagacgatatagtgaaacaaaatatagcggatgaaaaatttgtagattttgt -tatacacggtctagagcatcaatgtcctgctatacttcgaccattaattaggttgtttat -tgatatactattatttgttatagtaatttatatttttacggtacgtctagtaagtagaaa -ttatcaaatattgttggtgttggtggcgctagtcatcacattaactatttttttattact -ttatactataatagtactagactgacttctaacaaacatctcacctgccataaataaatg -cttgatattaaagtcttctatttctaacactattccatctgtggaaaataatactctgac -attatcgctaattgatacatcggtaagtgatatgcctataaagtaataatcttctttggg -cacatataccagtgtaccaggttctaacaacctatttactggtgctcctgtagcatactt -tttttttaccttgagaatatccattgtttgcttggtcaatagtgatatgtgattttttat -caaccactcaaaaaagtaattggagtgttcatatcctctacgggctattgtctcatgacc -gtgtatgaaatttaagtaacacgactgtggtagatttgttctatagagccggttgccgca -aatagatagaactaccaatatgtctgtacaaatgttaaacattaattgattaacagaaaa -aacaatgttcgttctgggaatagaaaccagattaaaacaaaattcattagaatatatgcc -acgtttatacatggaatataaaataactacagtttgaaaaataacagtatcatttaaaca -tttaacttgcggggttaatctcacaactttactgtttttgaactgttcaaaatatagcat -agatccatgagaaatacgtttagccgcctttaatagaggaaatccaaccgcctttctgga -tctcaccaacgacgatagttctgaccagcaactcatttcttcatcatccacctgttttaa -catataataggcaggagatagatatccatcattgcaatattccttctcgtaggcacacaa -tctaatattgataaaatctccattctcttctctgtatttattatcttgtctcggtggctg -attaggctgtggtctatcgttgttgaatctattttggtcattaaatctttcatttcttcc -tggtatatttctatcacctcgtttggttggatttttgtctatattatcgtttgtaacatc -ggtacgggtattcatttatcacaaaaaaaacttctctaaatgagtctactactagaaaac -ctcatcgaagaagataccatattttttgcaggaagtatatctgagtatgatgatttacaa -atggttattgctggtgcaaaatccaaatttccaagatctatgctttctatttttaatata -gtacctagaacgatgtcaaaatatgagttggagttgattcataacgagaatatcacaggg -gcaatgtttaccacaatgtataatataagaaacaatttgggtctaggcgatgataaacta -actattgaagccattgaaaactatttcttggatcctaacaatgaggttatgcctcttatc -attaataatacggatatgactaccgtcattcctaaaaaaagtggtaggagaaagaataag -aacatggttatcttccgtcaaggatcatcacctatcttgtgtattttcgaaactcgtaaa -aagattaatatttataaagaaaatatggaatccgtatcgactaagtatacacctatcgga -gacaacaaggctttgatatctaaatatgcgggaattaatatcctgaatgtgtattctcct -tccacgtccatgagattgaatgccatttacggattcaccaataaaaataaactagagaaa -cttagtactaataaggaactagaatcgtatagttctagccctcttcaagaacccattagg -ttaaatgattttctgggactattggaatgtgttaaaaagaatattcctctaacagatatt -ccgacaaaggattgattactataaatggagaatgttcctaatgtatactttaatcctgtg -tttatagagcccacgtttaaacattctttattaagtgtttataaacacagattaatagtt -ttatttgaagtattcgttgtattcattctaatatatgtattttttagatctgaattaaat -atgttcttcatgcctaaacgaaaaatacccgatcctattgatagattacgacgtgctaat -ctagcgtgtgaagacgataaattaatgatctatggattaccatggataacaactcaaaca -tctgcgttatcaataaatagtaaaccgatagtgtataaagattgtgcaaagcttttgcga -tcaataaatggatcacaaccagtatctcttaacgatgttcttcgcagatgatgattcatt -ttttaagtattttgctagtcaagatgatgaatcttcattatctgatatattgcaaatcac -tcaatatctagactttctgttattattattgatccaatcaaaaaataaattagaagctgt -gggtcattgttatgaatctctttcagaggaatacagacaattgacaaaattcacagactc -tcaagattttaaaaaactgtttaacaaggtccctattgttacagatggaagggtcaaact -taataaaggatatttgttcgactttgtgattagtttgatgcgattcaaaaaagaatcagc -tctagctaccaccgcaatagatcctgttagatacatagatcctcgtcgtgatatcgcatt -ttctaacgtgatggatatattaaagtcgaataaagttgaaaaataattaattctttattg -ttatcatgaacggcggacatattcagttgataatcggccccatgttttcaggtaaaagta -cagaattaattagacgagttagacgttatcaaatagctcaatataaatgtgtgactataa -aatattctaacgataatagatacggaacgggactatggacacatgataagaataattttg -cagcattggaagtaactaaactatgtgatgtcttggaagcaattacagatttctccgtga -taggtatagatgaaggacagttctttccagacattgttgaattctgtgagcgtatggcaa -acgaaggaaaaatagttatagtagccgcgctcgatgggacatttcaacgtagaccgttta -ataatattttgaatcttattccattatctgaaatggtggtaaaactaactgcagtgtgta -tgaaatgctttaaggaggcttccttttctaaacgattaggtacagaaaccgagatagaaa -taataggaggtaatgatatgtatcaatctgtgtgtagaaagtgttacatcgactcataat -attatattttttatctaaaaaactaaaaataaacattgattaaattttaatataatactt -aaaaatggatgttgtgtcgttagataaaccgtttatgtattttgaggaaattgataatga -gttagattacgaaccagaaagtgcaaatgaggtcgcaaaaaaactgccgtatcaaggaca -gttaaaactattactaggagaattattttttcttagtaagttacagcgacacggtatatt -agatggcgccaccgtagtgtatataggatctgctccaggtacacatatacgttatttgag -agatcatttctataatttaggagtgatcatcaaatggatgctaattgacggccgccatca -tgatcctattctaaatggattgcgtgatgtgactctagtgactcggtttgttgatgagga -atatctacgatccatcaaaaaacaactacatccttctaagattattttaatttctgatgt -gcgatccaaacgaggaggaaatgaacctagtactgcggatttactaagtaattatgctct -acaaaatgtcatgattagtattttaaaccccgtggcgtctagtcttaaatggagatgccc -gtttccagatcaatggatcaaggacttttatatcccacacggtaataaaatgttacaacc -ttttgctccttcatattcagctgaaatgagattattaagtatttataccggtgagaatat -gagactgactcgagttaccaaatcagacgctgtaaattatgaaaaaaagatgtattacct -taataagatagtccgcaacaaagtagttattaactttgattatcctaatcaggaatatga -ctattttcacatgtactttatgttgaggaccgtatactgcaataaaacatttcctactac -taaagcaaagatactatttctacaacaatctatatttcgtttcttaaatattccaacgac -atcaactgaaaaagttagtcatgaaccaatacaacgtaaaatatctagcaaagattctat -gtctaaaaacagaaatagcaagagatccgtacgcggtaataaatagaaacgtactactga -gatatactaccgatatagagtataatgatttagttactttaataaccgttagacataaaa -ttgattctatgaaaactgtgtttcaggtatttaacgaatcatccataaattatactccgg -ttgatgatgattatggagaaccaatcattataacatcgtatcttcaaaaaggtcataaca -agtttcctgtaaattttctatacatagatgtggtaatatctgacttatttcctagctttg -ttagactagatactacagaaactaatatagttaatagtgtactacaaacaggcgatggta -aaaagactcttcgtcttcctaaaatgttagagacggaaatagttgtcaagattctctatc -gtcctaatataccattaaaaattgttagatttttccgcaataacatggtaactggagtag -agatagccgatagatctgttatttcagtcgctgattaatcaattagtagagatgagataa -gaacattataataatcaataatatatcttatatctgtttagaaaaatgctaatattaaaa -tagctaacgctagtaatccaatcggaagccatttgatatctataatagggtatctaattt -cctgattcagatagcgtacggctatattctcggtagctactcgtttggaatcacagacat -tatttacatctaatttactatctgtaatggaaacgtttcccaatgaaatggtacaatcag -atacattacatcttgatatatttttttttaaagaggctggtaacaacgcatcgcttcgtt -tacatggctcgtaccaacaataatagggtaatcttgtatctattcctatccgtactatac -ttttatcaggataaatacatttacatcgtatatcgtctttgttagtatcacagaatgcat -aaatttgttcgtccgtcatgataaaaatttaaagtgtaaatataactattatttttatag -ttataataaaaagggaaatttgattgtataccttcggttctttaaaagaaactgacttga -taaaaatggctgtaatctctaaggttacgtatagtctatacgatcaaaaagagattaatg -ccacagatattatcattagtcatattaaaaatgacgacgatatcggtaccgttaaagatg -gtagactaggtgctatggatggggcattatgtaaaacttgtgggaaaacggaattggaat -gtttcggtcactggggtaaagtaagtatttataaaactcatatagttaagcctgaattta -tttcagaaattattcgtttactgaatcatatatgtattcattgcggattattgcgttcac -gagaaccgtattccgacgatattaacctaaaagagttatcggtacacgctcttaggagat -taaaggataaaatattatccaagaaaaagtcatgttggaacagcgaatgtatgcaaccgt -atcaaaaaattactttttcaaagaaaaaggtttgtttcgtcaacaagttggatgatatta -acgttcctaattctctcatctatcaaaagttaatttctattcatgaaaagttttggccat -tattagaaattcatcaatatccagctaacttattttatacagactactttcccatccctc -cgttgattattagaccggctattagtttttggatagatagtatacccaaagagacaaatg -aattaacttacttattaggtatgatcgttaagaattgtaacttgaatgctgatgaacagg -ttatccagaaggcggtaatagaatacgatgatattaaaattatttctaataacactacca -gtatcaatttatcatatatcacatccggcaaaaataatatgattagaagttatatcgtcg -ctcggcgaaaagatcagaccgctagatccgtaattggtcccagtacatctatcaccgtta -atgaggtaggaatgcccacatatattagaaatacacttacagaaaagatatttgttaatg -cctttacagtggataaagttaaacaactattagcatcaaaccaagttaaattttacttta -ataaacgattaaaccaattaacaagaatacgtcaaggaaagtttatcaaaaataaaatac -atttattgcctggtgattgggtagaagtagctgttcaagaatatacaagtattatttttg -gaagacaaccgtctctacatagatacaacgtcatcgcttcatctatcagagctaccgaag -gagatactatcaaaatatctcccggaattgccaactctcaaaatgctgattttgacggag -atgaagaatggatgatattggagcaaaatcctaaagccgtagttgaacaaagtattctta -tgtatccgacaacgttactcaaacacgatattcatggagcccccgtttatggatctattc -aagatgaaatcgtagcagcgtattcattgtttaggatacaagatctttgtttagatgaag -tattgaacatcttggggaaatatggaagagagttcgatcctaaaggtaaatgtaaattca -gcggtaaagatatctatacttacttgataggtgaaaagattaattatccgggtctcttaa -aggatggtgaaattattgcaaacgacgtagatagtaattttgttgtagctatgaggcatc -tgtcattggctggactcttatccgatcataaatcgaacgtggaaggtatcaactttatta -tcaagtcatcttatgtttttaagagatatctatctatatacggttttggggtgacattca -aagatctgagaccaaattcgacgttcactaataaattggaggctatcaacgtagaaaaaa -tagaacttatcaaagaagcatacgccaaatatctcaaagatgtaagagacgggaaaatag -ttccattatctaaagctttagaggcggactacttggaatccatgttatccaacttgacaa -atcttaatatcagagagatagaagaacatatgagacaaacgctgatagatgatccagata -ataacctcctgaaaatggccaaagcgggttataaagtaaatcccacagaactaatgtata -ttctaggtacttatggacaacagaggatagatggcgaaccagcagagactcgagtattgg -gtagagtcttaccttactatcttccagactctaaggatccagaaggaagaggttatattc -ttaattctttaacaaaaggattaacgggttctcaatattactttttgatgctggttgcaa -gatctcaatctactgatattgtctgtgaaacatcacgtaccggaacactggctagaaaaa -tcattaaaaagatggaggatatggtggtcgacggatacggacaagtagttataggtaata -cgctcatcaagtacgcagccaattataccaaaattctaggctcagtatgtaaacctgtag -atcttatctatccagatgagtccatgacttggtatttggaaattagtgctttgtggaata -aaataaaacagggattcgtttactctcagaaacagaaacttgcaaagaagacattggcgc -cgtttaatttcctagtattcgtcaaacccaccactgaggataatgctattaaggttaagg -atctgtacgatatgattcataacgtcattgatgatgtgagagagaaatacttctttacgg -tatctaatatagattttatggagtatatattcttgacgcatcttaatccttctagaatta -gaattacaaaagaaacggctattactatctttgaaaagttctatgaaaaactcaattata -ctctaggtggtggaactcctattggaattatttctgcacaggtattgtctgagaagttta -cacaacaagccctgtccagttttcacactactgaaaagagtggtgctgtaaaacaaaaac -ttggtttcaacgagtttaataacttgactaatttgagtaagaataagaccgaaattatca -ctctggtatccgatgatatctctaaacttcaatctgttaagattaatttcgaatttgtat -gtttgggagaattaaatccagacatcactcttcgaaaagaaacagatagatatgtagtag -acataatagtcaatagattatacatcaagagagcagaaataaccgaattagtcgtcgaat -atatgattgaacgatttatctcctttagcgtcattgtaaaggaatggggtatggagacat -tcattgaggacgaggataatattagatttactatctacctaaatttcgttgaaccggagg -aattgaatcttagtaagtttatgatggttcttccaggtgccgccaacaagggcaagatta -gtaaattcaagattcctatctctgactatacgggatataacgacttcaatcaaacaaaaa -agctcaataagatgactgtagaactcatgaatctaaaagaattgggttctttcgatttgg -agaacgtcaacgtgtatcctggagtatggaatacatacgatatctttggtattgaggccg -ctcgtggatacttgtgcgaagccatgttaaacacctatggagaaggtttcgattatctgt -accagccttgtgatcttctcgctagtttactatgtgctagttacgaaccagaatcagtta -ataaattcaagttcggtgcagctagtactcttaagagagctacgttcggagataataaag -cattgttaaacgcggctcttcataaaaagtcagaacctattaacgataatagtagctgcc -acttttttagcaaggtccctaatataggaactggatattacaaatactttatcgacttgg -gtcttctcatgagaatggaaaggaaactatctgataagatatcttctcaaaagatcaagg -agatagaagaaacagaagacttttaattcttatcaataacatatttttctatgatctgtc -ttttaaacgatggattttccacaaatgcgcctctcaagtccctcatagaatgatacacgt -ataaaaaatatagcataggtgatgactccttatttttagacattagatatgccaaaatca -tagccccgcttctatttactcctgcaacacaatgaaccaacacgggctcgtttcgttgat -cacatttagataagaaggcggtcacgtcgtcaaaatatttactaatatcagtagttgtat -catctaccaacggtatatgaataatattaatattagagttaggtaatgtatatttatcca -tcgtcaaatttaaaacatatttgaacttaacttcagatgatggtgcatccatagcatttt -tataatttcccaaatacacattatttgttactcttgtcattatagtgggagatttggctc -tgtgcatatctccagttgaacgtagtagtaagtatttatacaaacttttcttatccattt -ataacgtacaaatggataaaactactttatcagtaaacgcatgcaatttagaatacgtta -gagaaaaggctatagtaggcgtacaagcagccaagacatcaacacttatattttttgtta -ttatattggcaattagtgcgctattactctggtttcagacgtctgataatccagtcttta -atgaattaacgagatatatgcgaattaaaaatacggttaacgattggaaatcattaacgg -atagcaaaacaaaattagaaagcgatagaggtagacttctagccgctggtaaggatgata -tattcgaattcaaatgtgtggatttcggcgcctattttatagctatgcgattggataaga -aaacatatctgccgcaagctattaggcgaggtactggagacgcgtggatggttaaaaagg -cggcaaaagtcgatccatctgctcaacaattttgtcagtatttgataaaacacaagtcta -ataatgttattacttgtggtaatgagatgttaaatgaattaggttatagcggttatttta -tgtcaccgcattggtgttccgatcttagtaatatggaataagtgttagataaatgcggta -acaaatgttcctgtaaggaaccataacagtttagatttaacattaaagatgagcataaac -ataataaacaaaattacaatcaaacctataacattaatatcaaacaatccaaaaaatgaa -atcaatggagtagtaaacgtgtacataactcctggataacgtttagcagctaccgttcct -attctagaccaaaaatttggtttcatggtttcgaagcggtgttctgcaacaagacgagga -tcgtgttctacatatttggcagagttatccattatttgcctgttaatcttcatttcgttt -tcgattctggctatttcaaaataaaatcccgatgatagacctccagactttataatttca -tctacgatgttcagcgccgtagtaactctaataatataggcggataagctaacatcatac -cctcctgtatatgtaaatatggcatgatctttgtctattacaagctcggttttaacttta -tttcctgtaataatttctctcatctgtaggatatctattttcttgtcatgtattgccttc -aagacgggacgaagaaacgtaatatcctcaataacgttatcgttttctataataactaca -tattctacatttttattttctagctcggtaaaaaatttagaatcccatagggctaaatgt -ctagcgatatttcttttcgtttcctctgtacacatagtgttacaaaaccctgaaaagaag -tgagtatacttgtcatcatctctaatatttcctccagtccattgtataaacacataatcc -ttgtaatgatctggatcatcattgactatcacaacatctcttttttcttgcataacttca -ttgtccttcacatcatcgaacttctgatcattaatatgctcatgaacattaggaaatgtt -tctgatggaggtctatcaataactggcacaacaataacaggagttttcaccgccgccatt -tagttattgaaattaatcatatacaactctctaatacgagttatattttcgtctatccat -tgtttcacattgacatatttcgacaaaaagatataaaatgcgtattccaatgcttctctg -tttaatgaattactaaaatatacaaacacgtcactgtctggtaataaataatatcttaga -atattgtaacaatttattttgtattgcacatgttcgtgatctatgagttcttcttcaaat -ggcataggatctccgaatctgaaaacgtataaataggagttagaataataatatttgaga -gtattggtaatgtataaactctttagcggtataattagtttttttctctcgatttctatt -tttagatgtgatggaaaaatgactaattttgtagcattagtatcatgaactctaatcaaa -atcttaatatcttcgtcacatgttagctctttgaagtttttaagagatgcatcagttggt -tttacagatggagtaggtgcaacaattttttgtttaatgcatgcatgtattggagccatt -gtcttaactataatggtgcttgtatcgaaaaactttaatgcggataacggaagctcttcg -ccgcgactttctacgtcgtaattgggttctaatgccgatctctgaatggatactagtttt -ctaagttctaatgtaattctctgaaaatgtaaatccaattcctccggcattatagatgtg -tatacatcggtaaataaaactatagtatccaacgatcccttctcgcaaattctagtctta -accaagaaatcgtatataactacggagatggcgtatttaagagtggattcttctaccgtt -ttgttcttggatttcatataagaaactataaagtccgcactactgttaagaatgatcact -aacgcaactatatagttcaaattaagcatcttggaaacataaaataactctgtagatgat -acttgactttcgaataagtttgcagacaaacgaagaaagaacagacctctcttaatttca -gaagaaaactttttttcgtattcctgacgtctagagtttatatcaataagaaagttaaga -attagtcggttaatgttgtatttcattacccaagtttgagatttcataatattgtcaaaa -gacatgataatattaaagataaagcgctgactatgaacgaaatagctatatggttcgctc -aagaatatagtcttgttaaacgtggaaacgataactgtatttttaatcacgtcagcggca -tctaaattaaatataggtatatttattccacacactctacaatatgccacaccatcttca -taataaataaattcgttagcaaaattattaattttagtgaaatagttagcgtcaactttc -atagcttccttcaatctaatttgatgctcacatggcgcgaattctactctaacatccctt -ttccatgcctcaggttcatcgatctctataatatctagtttcttgcgtttcacaaacaca -ggctcgtctctcgcgatgagatctgtatagtaactatgtaaatgataactagatagaaag -atgtagctatatagatgacgatcctttaagagaggtataataactttaccccaatcagat -agactgttgttatggtcttcggaaaaagaatttttataaatttttccagtattttctaaa -tatacgtacttgatatctaagaaatccttaataataataggaatggataatccgtctatt -ttataaagaaatacatatcgcatattatacttttttttggaaattggaataccgatgtgt -ctacataaatacgcaaagtctaaatattttttagagaatcttagttggtccaaattcttt -tccaagtacggtaatagatttttcatattgaacggtatcttcttgatctctggttctaat -tccgcattaaatgatgaaactaagtcactatttttataactaacgattacatcacctcta -acatcatcatttaccaggatactgatcttcttttgtcgtaaatacatgtctaatgtgtta -aaaaaaagatcatacaagttatacgtcatttcatctgtagtattcttgtcattgaaggat -aaactcgtactaatctcttctttaacagtctgttcaaatttatatcctatatatgaaaaa -atagcaaccagtgtttgatcatccgcgtcaatattctgttctatcgtagtgtataacaat -cttatatcttcttctgtgatagtcgatacgttataaaggttgataacgaaaatattttta -tttcgtgaaataaagtcattgtaggattttggacttatattcgtgtctagtagatatgat -tttatttttggaatgatctcaattaaaatagtctctttagagtccatttaaagttacaaa -caactaggaaattggtttatgatgtataatttttttagtttttatagattctttattcta -tacttaaaaaatgaaaataaatacaaaggttcttgagggttgtgttaattgaaagcgata -aataatcataaattatttcattatcgcgatatccgttaagtttgtatcgtaatggcgtgg -tcaattacgaataaagcggatactagtagtttcacaaagatggctgaaatcagagctcat -ctaagaaatagcgctgaaaataaagataaaaacgaggatattttcccggaagatgtaata -attccatctactaagcccaaaaccaaacgaaccactactcctcgtaaaccagcggctact -aaaagatcaaccaaaaaggataaagaaaaggaggaagtggaagaagtagttatagaggaa -tatcatcaaacaactgaagaaaattctccacctccgtcatcatctcctggagtcggcgac -attgtagaaagcgtggccgctgtagagctcgatgatagcgacggggatgatgaacctatg -gtacaagttgaagctggtaaagtaaatcatagtgctagaagcgatctctctgacctaaag -gtggctaccgacaatatcgttaaagatcttaagaaaattattactagaatctctgcagta -tcgactgttctagaggatgttcaagcagctggtatctctagacaatttacttctatgact -aaagctattacaacactatctgatctagtcaccgagggaaaatctaaagttgttcgtaaa -aaagttaaaacttgtaagaagtaaatgcgtgcacttttttataaagatggtaaactgttt -accgataataattttttaaatcctgtatcagacgataatccagcgtatgaggttttgcaa -catgttaaaattcctactcatttaacagatgtagtagtatatgaacaaacgtgggaagag -gcattaactagattaatttttgtgggaagtgattcaaaaggacgtagacaatacttttac -ggaaaaatgcatatacagaatcgcaatgctaaaagagatcgtatttttgttagagtatat -aacgttatgaaacgaattaattgttttataaacaaaaatataaagaaatcgtccacagat -tccaattatcagttggcggtttttatgttaatggaaactatgttttttattagatttggt -aaaatgaaatatcttaaggagaatgaaacagtagggttattaacactaaaaaataaacac -atagaaataagtcccgatgaaatagttatcaagtttgtaggaaaggacaaagtttcacat -gaatttgttgttcataagtctaatagactatataaaccgctattgaaactgactgatgat -tctagtcccgaagaatttctgttcaacaaactaagtgaacgaaaggtatatgaatgtatc -aaacagtttggtattagaatcaaggatctccgaacgtatggagtcaattatacgttttta -tataatttttggacaaatgtaaagtccgtatctcctcttccatcaccaaaaaagttgata -gcattaactatcaaacaaactgctgaagtggtaggtcatactccatcaatttcaaaaaga -gcttatatggcaacgactattttagaaatggtaaaggataaaaattttttagacgtagta -tctaaaactacgttcgatgaattcctatctatagtcgtagatcacgttaaatcatctacg -gatggatgataatagatctttacacaaataattacaagaccgataaatggaaatggataa -acggatgaaatctctcgctatgacagctttcttcggagagctaaacacgttagatattat -ggcattgataatgtctatatttaaacaccatccaaacaataccattttttcagtggataa -ggatggtcaatttatgattgatttcgaatacgataattataaggcttctcaatatttgga -tctgaccctcactccgatatctggaaatgaatgcaagactcacgcatctagtatagccga -acaattggcgtgtgtggatattattaaagaggatattagcgaatatatcaaaactactcc -ccgtcttaaacgatttataaaaaaataccgcaatagatcatatactcgtatcagtcgaga -tacagaaaagcttaaaatagctctagctaaaggcatagattacgaatatataaaagacgc -ttgttaataagtaaatgaaaaaaaactagtcgtttataataaaacacaatatggatgcca -acatagtatcatcttctactattgcgacgtatatagacgctttagcgaagaatgcttcag -aattagaacagaggtctaccgcatacgaaataaataatgaattggaactagtatttatta -aaccgccattgattacgttgacaaatgtagtaaatatctccacgattcaggaatcgttta -ttcgatttaccgttactaataaggaaggtatcaaaattagaactaagattccattatcta -aggtacatggtctagatgtaaaaaatgtgcagttggtagatgctatagataacatagttt -gggaaaagaaatcattagtgacggaaaatcgtcttcacaaagaatgcttgttgagactat -caacagaggaacgtcatatatttttggattacaagaaatatggatcctctatccgactag -aattagtcaatcttattcaagcaaaaacaaaaaactttacgatagactttaagctaaaat -attttctaggatctggcgctcaatctaaaagttctttattgcacgctattaatcatccaa -agtcaaggcctaatacatctctggaaatagaatttacacctagagacaatgaaacagttc -catatgatgaactaataaaggaattgacgactctctcgcgtcatatatttatggcttctc -cagagaatgtaattctttctccacctattaacgcacctataaagacttttatgttgccta -aacaagatatagtaggtctggatctggaaaatctatatgccgtaactaagactgacggca -ttcctataactatcagagttacatcaaaagggttgtattgttattttacacatcttggtt -atattattagatatccagttaagagaacaatagattccgaagtagtagtctttggtgagg -cagttaaggataagaactggaccgtatatctcattaagctaatagagcccgtaaatgcaa -tcagtgatagactagaagaaagtaagtatgttgaatctaaactagtggatatttgtgatc -ggatagtattcaagtcaaagaaatacgaaggtccgtttactacaactagtgaagtcgtcg -atatgttatctacatatttaccaaagcaaccagaaggtgttattctgttctattcaaagg -gacctaaatctaacattgattttaaaatcaaaaaggagaatactatagaccaaactgcaa -atgtagtatttaggtacatgtccagtgaaccaattatctttggagagtcgtctatcttta -tagagtataagaaatttaccaacgataaaggctttcctaaagaatatggttctggtaaga -ttgtgttatataacggcgttaattatctaaataatatctattgtttggaatatattaata -cacataatgaagtgggtattaagtccgttgttgtacctattaagtttatagcagaattct -tagtcaatggagaaatacttaaacctagaatcgataaaaccatgaaatatattaactcag -aagactattatggaaatcaacataatatcatagtcgaacatttaagagatcaaagcatca -aaataggagatgtctttaacgaggataaactatcggatgttggacatcaatacgctgcca -acaacgataaatttagattaaatccagaagttagttattttactaataaacgaactagag -ggccgttgggaattttatcaaactacgtcaagactcttcttatttctatgtattgttcca -aaacatttttagacgattccaacaaacgaaaggtattagcgattgattttggaaacggtg -ctgacctggaaaaatacttttatggagagattgcgttattggtagcgacggatccggatg -ctgatgctatagctagaggaaatgaaagatacaacaaattaaattctggaattaaaacca -agtactacaaatttgactacattcaggaaactattcgatccgatacatttgtctctagtg -tcagagaagtattctattttggaaagtttaatatcattgactggcagttcgctattcatt -attcttttcatccaagacattatgctacagtcatgaataacttatccgaactaactgctt -ctggaggcaaggtattaattactaccatggatggagacaaattatcaaaattaaccgata -aaaagacttttataattcataagaatctacctagtagcgaaaactatatgtctgtagaaa -aaatagctgatgatagaatagtggtatataatccatcaacaatgtctactccaatgactg -aatacattatcaaaaagaacgatatagtcagagtgtttaacgaatacggatttgttcttg -tagataatgttgatttcgctacaattatagaacgaagtaaaaagtttattaatggcgcat -ctacaatggaagatagaccgtctacaagaaactttttcgaactaaatagaggagccatta -aatgtgaaggtttagatgtcgaagacttacttagttactatgttgtttatgtcttttcta -agcggtaaataataatatggtatgggttctgatatccccgttctaaatgcattaaataat -tccaatagagcgatttttgttcctataggaccttccaactgtggatactctgtattatta -atagatatattaatacttttgtagggtaacagaggttctacgtcttctaaaaataaaagt -tttataacatctggcctgttcataaataaaaacttggcgattctatatatactcttatta -tcaaatctagccattgtcttatagatgtgagctactgtaggtgtaccatttgattttctt -tctaatactatatatttctctcgaagaagttcttgcagatcatctgggaataaaatacta -ctgttgagtaaatcagttattttttttatatcgatattgatggacatttttatagttaag -gataataagtatcccaaagtagataacgacgataacgaagtatttatacttttaggaaat -cacaatgactttatcagatcaaaattaacaaaattaaaggagcatgtatttttttctgaa -tatattgtgactccagatacatatggatctttatgcgtcgaattaaatgggtctagtttt -cagcacggtggtagatatatagaggtggaggaatttatagatgctggaagacaagttaga -tggtgttctacatccaatcatatatctgaagatatacacactgataaatttgtcatttat -gatatttatacgtttgattcgttcaagaataaacgattggtatttgtacaggtacctcca -tcattaggagatgatagctatttaactaatccgttattgtctccgtattatcgtaattca -gtagccagacaaatggtcaatgatatgatttttaatcaagattcatttttaaaatattta -ttagaacatctgattagaagccactatagagtttctaaacatataacaatagttagatac -aaggataccgaagaattaaatctaacaagaatatgttataatagagataagtttaaggcg -tttgtattcgcttggtttaacggcgtttcggaaaatgaaaaggtactagatacgtataaa -aaggtatctgatttgatataatgaattcagtgactatatcacacgcaccatatactatta -cttatcacgatgattgggaaccagtaatgagtcaattggtagagttttataacgaagtag -ccagttggttgctacgcgacgagacgtcgcctattcctgataagttctttatacaattga -aacagccgcttagaaataaacgagtatgtgtgtgtggtatagatccgtatccaaaagatg -gaactggtgtaccgttcgaatcaccaaattttacaaaaaaatcaattaaggagatagctt -catctatatctagattaaccggagtaattgattataaaggttataaccttaatataatag -acggggttataccctggaattattacttaagttgtaaattaggagaaacaaaaagtcacg -cgatttactgggataagatttccaagttactgctacagcatataactaaacacgttagtg -ttctttattgtttgggtaaaacagatttctcgaatatacgggcaaagttagaatccccgg -taactaccatagtgggatatcatccagcggccagagaccaccaattcgagaaagatcgat -catttgaaattatcaacgttttactggaattagacaacaagacacctataaattgggctc -aagggtttatttattaatgctttagtgaaattttaacttgtgttctaaatggatgcggct -attagaggtaatgatgttatctttgttcttaagactataggtgtcccgtcagcatgcaga -caaaatgaagatccaagattcgtagaagcatttaaatgcgacgagttagaaagatatatt -gataataatccagaatgtacactattcgaaagtcttagggatgaggaagcatactctata -gtcagaattttcatggatgtagatttagacgcgtgtctagacgaaatagattatttaacg -gctattcaagattttattatcgaggtgtcaaactgtgtagctagattcgcatttacagaa -tgcggtgccattcatgaaaatgtaataaaatccatgagatctaatttttcattgactaag -tctacaaatagagataaaacaagttttcatattatctttttagacacgtataccactatg -gatacattgatagctatgaaacgaacactattagaattaagtagatcatctgaaaatcca -ctaacaagatcgatagacactgccgtatataggagaaaaacaactcttcgggttgtaggt -actaggaaaaatccaaattgcgacactattcatgtaatgcaaccacctcacgataatata -gaagattacctattcacttacgtggatatgaacaacaatagttattacttttctctacaa -cgacgattggaggatttagttcctgataagttatgggaaccagggtttatttcgttcgaa -gacgctataaaaagagtttcaaaaatattcattaattctataataaactttaatgatctc -gatgaaaataattttacaacggtaccactggtcatagattatgtaacaccttgtgcatta -tgtaaaaaacgatcgcataaacatccgcatcaactatcgttggaaaatggtgctattaga -atttacaaaactggtaatccacatagttgtaaagttaaaattgttccgttggatggtaat -aaactgtttaatattgcacaaagaattttagacactaactctgttttattaaccgaacga -ggagaccatatagtttggattaataattcatggaaatttaacagcgaagaacccttgata -acaaaactaattctatcaataagacatcaactacctaaggaatattcaagcgaattactc -tgtccgaggaaacgaaagactgtagaagctaacatacgagacatgttagtagattcagta -gagaccgatacctatccggataaacttccgtttaaaaatggtgtattggacctggtagac -ggaatgttttactctggagatgatgctaaaaaatatacgtgtactgtatcgaccggattt -aaatttgacgatacaaaattcgtcgaagacagtccagaaatggaagagttaatgaatatc -attaacgatatccaaccattaacggatgaaaataagaaaaatagagagctgtatgaaaaa -acattatctagttgtttatgtggtgctaccaaaggatgtttaacattcttttttggagaa -accgcaactgggaagtcgacaaccaaacgtttgttaaagtctgctatcggtgacctgttt -gtcgagacgggtcaaacaattttaacagatgtattggataaaggacctaatccatttatc -gctaatatgcatttaaaaagatctgtattctgtagcgaactacctgattttgcatgtagt -ggatcaaagaaaattagatctgataatattaaaaagttgacagaaccttgtgtcattgga -agaccgtgtttctccaataaaattaataatagaaaccatgcgacaatcattatcgatact -aattacaaacctgtctttgataggatagataacgcattaatgagaagaattgccgtcgtg -cgattcagaacacacttttctcaaccttctggtagagaggctgctgaaaataatgacgcg -tacgataaagtcaaactattagacgagggattagatggtaaaatacagaataatagatat -agattcgcatttctatacttgttggttaaatggtacaaaaaatatcatattcctattatg -aaactatatcctacaccggaagagattccggactttgcattctatctcaaaataggtact -ctgttggtatctagctctgtaaagcatattccattaatgacggacctctccaaaaaggga -tatatattgtacgataatgtggttactcttccgttgactactttccaacagaaaatatcc -aagtattttaattctagactatttggacacgatatagagagcttcatcaatagacataag -aaatttgccaatgttagtgatgaatatctgcaatatatattcatagaggatatttcatct -ccgtaaatatatgccatatatttatagaatatatcacatatctaaatgaataccggaatc -atagatttatttgataatcatgttgatagtataccaactatattacctcatcagttagct -actttagattatctagttagaactatcatagatgagaacagaagcgtgttattgttccat -attatgggatcgggtaaaacaataatcgctttgttgttcgccttggtagcttccagattt -aaaaaggtttacattttagtaccgaacatcaacatcttaaaaattttcaattataatatg -ggtgtagctatgaacttgtttaatgacgaattcatagctgagaatatctttattcattcc -acaacaagtttttattctcttaattataacgataacgtcattaattataacggattaagt -cgctacaataactctatttttatcgttgatgaggcacataatatttttgggaataatact -ggagaacttatgaccgtgataaaaaataaaaacaagattccttttctactattgtctgga -tctcccattactaacacacctaatacgctgggtcatattatagatttaatgtccgaagag -acgatagattttggtgagattattagtcgtggtaagaaagtaattcagacacttcttaac -gaacgcggagtgaatgtactcaaggatttgcttaaaggaagaatatcatattacgaaatg -ccggacaaagatctaccaacaataagatatcacggacgtaaatttctagatactcgagta -gtatattgtcacatgtctaaacttcaagagaaagattatatgattactagacggcagcta -tgttatcatgaaatgtttgataaaaatatgtataacgtgtcaatggcagtattgggacaa -cttaatctgatgaataatttagatacgttatttcaggaacaggataaggaattgtaccca -aatctgaaaataaataatggagtgttatacggtgaagaattggtaacgttaaacattagt -tccaaatttaagtactttatcaatcggatacagacactcaagggaaaacactttatatac -ttctctaattctacatatggtggattggtaattaaatatatcatgctcagtaatggatat -tctgaatataatggttctcagggaactaatccacatatgataaacggcaaaccaaaaaca -tttgctatcgttactagtaaaatgaaatcgtctttagaggatctattagatgtgtataat -tctcctgaaaacgatgatggcaatcaattgatgtttttgttttcgtcaaacattatgtct -gaatcctatactctgaaagaggtaaggcatatttggtttatgactatcccggatactttt -tctcaatacaaccaaattcttggacgatctattagaaaattctcttacgtcgatatttct -gaacccgttaatgtatatcttttagcagccgtatattcagatttcaatgacgaagtgacg -tcattaaacgattatacacaggatgaattgattaatgttttaccctttgacatcaaaaag -ctgttgtatctaaaatttaagactaaagaaacgaatagaatatactctattcttcaagag -atgtctgaaacgtattctcttccaccacatccatcaattgtaaaagttttattgggagaa -ttggtcagacaatttttttataataattctcgtattaagtataacgactccaagttactt -aaaatggttacatcagttataaaaaataaagaagacgctaggaattacatagatgatatt -gtaaacggtcacttctttgtatcgaataaagtatttgataaatctcttttatacaaatac -gaaaacgatattattacagtaccgtttagactttcctacgaaccatttgtttggggagtt -aactttcgtaaagaatataatgtggtatcttctccataaaactgatgagatatataaaga -aataaatgtcgagctttgttaccaatggatatcttccagttacattggaaccacatgagt -tgacgttagacataaaaactaatattaggaatgccgtatataaggcgtatctccatagag -aaattagtggtaaaatggccaagaaaatagaaattcgtgaagacgtggaattacctctcg -gtgaaatagttaataattctgtagttataaacgttccgtgtgtaataacctacgcatatt -atcacgttggggatatagtcagaggaacattaaacatcgaagatgaatcaaatgtaacta -ttcaatgtggagatttaatctgtaaactaagtagagattcgggtactgtatcatttagcg -attcaaagtactgcttttttcgaaatggtaatgcgtatgataacggcatcgaagtctccg -ccgttctaatggaggctcaacaaggtaccgaatctagttttgtttttctcgcgaatatcg -ttgactcataagaaagagaatagcggtgagtataaatacgaatactatggcaataattgc -gaatgttttattcccttcgatatatttttgataatatgaaaaacatgcctctctcaaatc -agacaaccatttcataaaatagttctctcgcactggtgaggtggttgcagctcgtataat -ctccccagaataatatacttgcgtgtcgtcgttcaatttatacggatttctataattctc -tgttatataatgaggtttaccctcatgattagacgacgacaatagtgttctgaatttaga -tagttgatcagaatgaatgtttattggtgttggaaaaattatccatgctgcgtctgcaga -gtggttgatagttgttcctagatatgtaaaataatccaacgtactaggtagcaaattgtc -tagataaaatactgaatcaaatggcgcagacatattagcggatctaatggaatccaattg -attgactatcttttgaaaatatacatttttatgatctgatacttgtaagaatatagcaat -aatgataattccatcatcgtgtttttttgcctcttcataagaactatattttttcttatt -ccaatgaaccagattaatctctccagagtatttgtatacatctatcaagtgattggatcc -ataatcgtcttcctttccccaatatatatgtattgttgataacacatattcattggggag -aaaccctccacttatatatcctcctttaaaattaatccttactagttttccagtattctg -gatagtggttggtttcgactcattataatgtatgtctaacgtcttcaatcgcgcgtcaga -aattgcttttttagtttctatattaataggagatagttgttgaggcatagtaaaaatgaa -atgataactgtctagaaatagctcttagtatgggatttacaatggatgaggaagtgatat -ttgaaactcctagagaattaatatctattaaacgaataaaagatattccaagatcaaaag -acacgcacgtgtttgctgcgtgtataacaagtgacggatatccgttaataggagctagaa -gaacttcattcgcattccaggcgatattatctcaacaaaattcagattctatctttagag -tatccactaaactattacggtttatgtactacaatgaactaagagaaatctttagacggt -tgagaaaaggttctatcaacaatatcgatcctcacttcgaagagttaatattattgggtg -gtaaactagataaaaaggaatctattaaagattgtttaagaagagaattaaaagaggaaa -gtgatgaacatataacagtaaaagaattcggaaatgtaattctaaaacttacaacgagtg -ataaattatttaataaagtatatataggttattgcatggcatgttttattaatcaatcgt -tggaggatttatcacatactagtatttacaatgtagaaattagaaagattaaatcgttaa -atgattgtattaacgacgataaatacgaatatctgtcttatatttataatatactaatta -atagtaaatgagcttttacagatctagtataattagtcagattattaagtataatagacg -actagctaagtctattatttgcgaggatgactctcaaattattacactcacggcattcgt -taaccaatgcctatggtgtcataaacgagtatccgtgtccgctattttattaactactga -taacaaaatattagtatgtaacagacgagatagttttctctattctgaaataattagaac -tagaaacatgtatagaaagaaacgattatttctgaattattccaattatttgaacaaaca -ggaaagaagtatactatcgtcatttttttctctagatccagctactgctgataatgatag -aataaacgctatttatccgggtggtatacccaaaaggggtgagaacgttccagagtgttt -atccagggaaatcaaagaagaagttaatatagacaattcttttgtattcatagacactcg -tttttttattcatggtatcatagaagataccattattaacaaattttttgaggtaatttt -ctttgttggacgaatatctctaacgagtgatcaaattattgatacctttaaaagtaatca -tgaaataaaggatctaatatttttagatccaaattcaggtaatggactccaatacgaaat -tgcaaaatatgctctagatactgcaaaacttaaatgttacggtcatagaggatgttatta -tgaatcattaaaaaaattaactgaggatgattgattagaaaatataaattaatttaccat -cgtgtatttttataacgggattgtctggcatatcatgtagatagttaccgtctacatcgt -atactctaccatctacgcctttaaatcctctatttattgatattaatctattagaattgg -aataccaaatattagtaccctcaattagtttattggtaatattttttttagacgatagat -cgatggctcttgaaaccaaggttttccaaccggactcattgtctatcggtgagaagtctt -tttcattagcatgaatccattctaatgatgtatgtttaaacactctaaacaattgtacaa -attcttttgatttgttttgaatgatttcaaataggtcttcgtctacagtaggcataccat -tagataatctagccattataaagtgcacgtttacatatctacgttctggaggagtaagaa -cgtgactattgagacgaatggctcttcctactatctgacgaagagacgcctcgttccatg -tcatatctaaaatgaagatatcattgattgagaagaaactaataccctcgcctccgctag -aagagaatacgcatgttttaatgcattctccgttagtgtttgattcttggttaaactcag -ccaccgccttgattctagtatcttttgttctagatgagaactctatattagagataccaa -agactttgaaatatagtaataagatttctattcctgactgattaacaaatggttcaaaga -ctagacatttaccatgggatgctaatattcccaaacatacatctataaatttgacgcttt -tctcttttaattcagtaaatagagagatatcagccgcaatagcatcccctcccaatagtt -ctccctttttaaaggtgtctaatgcggatttagaaaattctctatctcttaatgaatttt -taaaatcattatatagggttgctatctcttgtgcgtattctcccggatcacgattttgtc -tttcaggaaagctatcgaatgtaaacgtagtagccatacgtctcagaattctaaatgatg -atataccagtttttatttctgcgagtttagccttttgataaatctcttcttgcttttttg -acatattaacgtatcgcattaatactgttttcttagcgaatgatgcagacccttccacat -catcaaaaatagaaaactcgttattaactatgtacgaacataggcctcctagtttggaga -ctaattctttttcatcgactagacgtttattctcaaatagcgattggtgttgtaaggatc -ctggtcgcagtaagttaaccaacatggtgaattcttgcacactattaacgataggtgtag -ccgataaacaaatcatcttatggttttttaacgcaatggtcttagataaaaaattatata -ctgaccgagtaggacggatcttaccatcttctttgattaatgatttagaaatgaagttat -gacattcatcaatgatgacgcatattctactcttggaattaatagttttgatattagtaa -aaaatttatttctaaaattttgatcatcgtaattaataaaaatacaatccttcgttatct -ctggagcgtatctgagtatagtgtttatccaaggatcttctatcaaagccttttttacca -ataagataattgcccaattcgtataaatatccttaagatgtttgagaatatatacagtag -tcattgttttaccgacacctgtttcatggaacaataaaagagaatgcatactgtctaatc -ctaagaaaactcttgctacaaaatgttgataatccttgaggcgtactacgtctgacccca -tcatttcaacgggcatattagtagttctgcgtaaggcataatcgatataggccgcgtgtg -atttactcatttatgagtgataagtaataactatgttttaaaaatcacagcagtagttta -actagccttctctgatgtttgttttcgatactttttgaatcagaagtcatactagaataa -agcagcgagtgaacgtaatagagagcttcgtatactctattcgaaaactctaagaactta -ttaatgaattccgtatccactggatcgtttaaaatactaaattgaacagtgttcacatcc -ttccaagacgaagacttagtgacggacttaacatgagacataaataaatccaaatttttt -ttataaacatcactagccaccataatggcgctatctttcaaccaactatcgcttacgcat -tttaacagtctaacatttttaaagagactacaatatattctcatagtatcgattacacct -ctaccgaatagagtgggaagtttaataatacaatatttttcgtttacaaaatcaaataat -ggtcgaaacacgtcgaaggttaacatcttataatcgctaatgtatagattgttttcagtg -agatgattattagatttaatagcatctcgttcacgtttgaacagtttattgcgtgcgctg -aggtcggcaactacggcatccgctctagtactcctcccataatactttacgctattaatc -tttaaaatttcatagactttatctagatcgctttctggtaacatgatatcatgtgtaaaa -agttttaacatgtcggtcggcattctatttagatcattaactctagaaatctgaagaaag -taattagctccatattccagactaggtaatgggcttttacctaaagacaagttaagttct -ggcaatgtttcataaaatggaagaaggacatgtgtcccctcccggatattttttacaatt -tcatccatttacaactctatagtttgttttcattattattagttattatctcccataatc -ttggtaatacttacaccttgatcataagataccttatacaggtcattacatacaactacc -aattgtttttgtacataatagattggatgattgatatccatggtggaataaactactcga -acagatagtttatctttccccctagatacattggccgtaatagttgtcggcctaaagaat -atctttggtgtaaagttaaaagttagggttcttgttccattattgctttttgtcagtagt -tcgttataaattctcgagatgggcccgttctctgaatatagaacatcatttccaaatcta -acttctagtctagaaataatatcggtcttatttttaaaatctattcccttgatgaatgga -tcgttaataaacaaatccttggcctttgattcggctgatctattatctccgttatagacg -ttacgttgactagtccaaagacttacaggaatagatgtatcgatgatgttgatagtatgt -gatatgtgagcaaagactgttctcttggtggcgtcgctatatgttccagtaatggcggaa -aactttttagaaatgttatatataaaagaattttttcgggttccaaacattaacagatta -gtatgaagataaacactcatattatcaggaacattatcaatttttacataaacatcggca -tcttgaatagaaacaacaccatcttctggaacctctacgatctcggcagattccggataa -ccagtcggtggaccatcactaacaataactagatcatccaacaatctactcacatatgcg -tctatataatctttttcatcttgtgagtaccctggatacgaaataaatttgttatcagta -tttccataataaggtttagtataaacagagagagatgttgctgcatgaacttcggttact -gtcgccgttggttggtttatttgacctattactctcctaggtttctctataaatgatggt -ttaatttgtacattcttaaccatatatccaataaagctcaattcaggaacataaacaaat -tctttgttgaacgtttcaaagtcgaacgaagagtcacgaataacgatatcggatactgga -ttgaaggtcaccgttacggtaatttttgaatcggatagtttaagactactgaatgtatct -tccacatcaaacggagttttaatataaacgtatactgtagatggttctttaatagtgtca -ttaggagttaggccaatagaaatatcattaagttcactagaatatccagaatgtttcaaa -gcaattgtattattgatacaattattatataattcttcgccctcaatttcccaaataaca -ccgttacacgaagagacagatacatgattaatacatttatatccaacatatggcacgtaa -ccgaatcttcccatacctttaacttctggaagttccaaactcagaaccaaatgattaagc -gcagtaatatactgatccctaatttcgaagctagcgatagcctgattgtctggcccatcg -tttgtcataactccggatagagaaatatattgcggcatatataaagttggaatttgacta -tcaactgcgaagacattagaccgtttaataaagtcatccccaccgatcaaagaattaatg -atagtattattcattttctatttaaaatggaaaaagcttacaataaactccgtagagaaa -tatctataatttgtgagttttccttaaagtaacagcttccgtaaacaccgtctttatctc -ttagtaagtttattgtatttatgaccttttccttatcttcatagaatactaaaggcaata -aagaaatttttggttcttctctaagagctacgtgagacttaaccatagacgccaacgaat -ccctacatattttagaacagaaatacccaacttcaccacccttgaatgtctcaatactaa -taggtctaaaaaccaaatcttgattacaaaaccaacacttatcaattacactatttgtct -taatagacatatctgccatagatttataatactttggtagtatacaagcgagtgcttctt -ctttagcgggcttaaagactgctttaggtgctgaaataaccacatctggaagacttactc -gcttagccatttaattacggaactatttttttatacttctaatgaacaagtagaaaacct -ctcatctacaaaaacatactcgtgtccataatcctctaccatagtaacacgttttttaga -tctcatatgtgctaaaaagttttcccatactaattggttactattatttttcgtataatt -tttaacagtttgaggttttagatttttagttacagaagtgatatcgaatattttatccaa -aaagaatgagtaattaattgtcttagaaggagtgttttcttggcaaaagaataccaagtg -cttaaatatttctactacttcattaatcttttctgtactcagattcagtttctcatcttt -tacttgattgattatttcaaagactaacttataatcctttttatttattctctcgttagc -cttaagaaaactagatacaaaatttgcatctacatcatccgtggatatttgatttttttc -catgatatccaatagttccgagataatttctccagaacattgatgagacaataatctccg -caatacatttctcaaatgaataagtttattagacacgtggaagtttgactttttttgtac -ctttgtacatttttgaaatacagactcgcaaaaaatacaatattcatatccttgttcaga -tactataccgttatgtctacaacagctacataatcgtagattcatgttaacactctacgt -atctcgtcgtccaatattttatataaaaacattttatttctagacgttgtcagaaaatcc -tgtaatatttttagtttttttggttgtgaataaagtatcgccctaataatattggtaccg -tcttccgacaatatagtagttaaattatccgagcatgtagaagaacaccgcttaggcgga -ttcagtacaatgttatatttttcgtaccaactcatttaaatatcataatctaaaatagtt -ctgtaatatgtctagcgctaatatattgatcataatcctgtgcataaattaagatacaac -aatgtcttgaaatcatcgacatggcttcttccatagttagaagatcatcgtcaaagttag -caacgtgattcatcaacatttgctgttttgaggcagcaaatactgaaccatcaccattca -accattcataaaaaccatcgtctgaatccattgataatttcttgtactggtttttgagag -ctcgcatcaatctagcatttctagctcccggattgaaaacagaaagaggatcgtacatcc -aaggtccattttctgtaaatagaatcgtataatgtcccttcaagaagatatcagacgatc -cacaatcaaagaattggtctccgagtttgtaacagactgcggactttaacctatacatga -taccgtttagcatgatttctggtgatacgtcaatcggagtatcatctattagagatctaa -agccggtgtaacattctccgccaaacatattcttattctgacgtcgttctacataaaaca -tcattgctccattaacgataacaggtgaatgaacagcactacccatcacattagttccca -atggatcaatgtgtgtaactccagaacatcttccatagcctatgttaggaggagcgaaca -ccactcttccactattgccatcgaatgccatagaataaatatccttggaattgatagaaa -tcggactgtcggatgttgttatcatcttcataggattaacaacgatgtatggtgcagcct -gaagtttcatatcgtaactgatgccgttcataggtctagccacagaaaccaacgtaggtc -taaatccaactatagacaaaatagaagctaatatctgttcctcatctgtcataacttgag -agcatccagtatgaataatcttcattagatggggatctaccgcatcatcatcgttacaat -aaaaaattcccattctaatgttcataattgcttttctaatcatggtatgaatgtttgctc -tctgaatctctgtggaaattagatctgatacacctgtaatcactatcggattatcctccg -taagacgattaaccaacaacatataattataagactttactcttctaaattcataaagtt -gctggattagactatatgtgtctccatgtacatacgcgttctcgagcgcaggaagtttaa -taccgaatagtgccatcagaataggatgaatgtagtaattagtttctggttttctataaa -taaaagacaaatcttgtgaactagacatatcggtaaaatgcatggattggaatcgtgtag -tcgacagaagaatatgatgattagatggagagtatattttatctaactctttgagttggt -caccgattctaggactagctcgagaatgaataagtactaagggatgagtacatttcacag -aaacactggcgttgttcaacgtactctttacatgggaaaggagttgaaatagctcgtttc -tatttgtcctgacaatatttagtttattcataatattaagcatatcctgaatagtaaagt -tagatgtgtcatacttgttagtagttagatatttagcaattgcattcccatcatttctca -atctcgtactccaatcatgtgtggatgctacttcgtcgatggaaaccatacaatcctttt -tgataggctgttgagattgatcatttcctgtacgtttaggtttggtacgttgatttctag -cccctgctgatataaagtcatcgtctacaatttgggataatgaattacatacactacaag -acaaagatttatcagaagtgtgaatatgatcttcatctaccaaagaaagagtttgattag -tataactagattttagtcccgcgttagatgttaaaaaaacatcgctattgaccacggctt -ccattatttatattcgtagtttttactcgaaagcgtgattttaatatccaatcttattac -ttttggaatcgttcaaaacctttgactagttgtagaatttgatctattgccctacgcgta -tactcccttgcatcatatacgttcgtcaccagatcgtttgtttcggcctgaagttgacgc -atatctttttcaacactcgacatgagatccttaagggtcatatcgtctagattttgttga -gatgctgctcctggatttggattttgttgtgctgttgtacatactgtaccaccagtaggt -gtaggagtacatacagtggccacaataggaggttgaagaggtgtaaccgttggagtagta -caagaaatacttccatccgattgttgtgtacatgtggttgttggtaacgtctgagaaggt -tgggtagatggcggtgtcgtcatcttttgatctttattaaatttagagataatatcctga -acagtattgctcggcgtcaacgctggaaggagtgtactcgccggcgcatcagtatctgta -gacaaccaatcaaaaagattagacatatcagatgatgtattagtttgttgacgtggtttt -agtacaggagcagtactactaggtagaagaataggagccggtgtaggtgtcggaaccggc -tgtggagttatatgaatagttggttgtagcggttgggtaggctgtctgctggcggtcatc -atattatctctagctagttgttctcgcaactgtctttgataatacgactcttgagacttt -agtcctatttcaatcgcttcatcctttttcgtatccggatccttttcttcagaataatag -attgacgactttggtgtagaggattctgccagcccctgtgagaacttgttaaagaagtcc -atttaaggctttaaaattgaattgcgattataagattaaatggcagacacggacgatatt -atcgactatgaatccgatgatctcaccgaatacgaggatgatgaagaagatggagagtca -ctagaaactagtgatatagatcccaaatcttcttataagattgtagaatcaacatccact -catatagaagatgcgcattccaatcttaaacatatagggaatcatatatctgctcttaaa -cgacgctatactagacgtataagtctatttgaaatagcgggtataatagcagaaagctat -aacttgcttcaacgaggaagattacctctagtttcagaattttctgacgaaacgatgaag -caaaatatgctacatgtaattatacaagagatagaggagggttcttgtcctatagtcatc -gaaaagaacggagaattgttgtcggtaaacgattttgataaagatggtctaaaattccat -ctagactatattatcaaaatttggaaacttcaaaaacgatattagaatttatacgaatat -cgttctctaaatgtcacaatcaagtctctcatattcagcagtttattgtcgtactttata -tcgtgttcattaacgatattttgcaaaatagtaatgattctatcttccttcgatagatat -tcttcagagattattgtcttatattctttcttgttatccgatatgaatttgataagactt -tgaacattattaatacccgtctgtttaattttttctatagatattttagttttggtagat -tctatggtgtctgttaataggcatccaacatcgacattcgacgtcaattgtctataaatc -agagtataaattttagaaataacattagcaaattgttgtgcgttgatgtcgttattctga -aacagtatgattttaggtagcattttcttaacaaagagaacgtatttattgttactcagt -tgaacagatgatatatccagattactaacgcatctgattccatataccaaactttcagaa -gaaatggtgtacaattgtttgtattcattcaatgtctccttttcagaaattagtttagag -tcgaatactgcaataattttcaagagatagttttcatcagataagattttatttagtgta -gatatgataaaactattgttttgttggagaacttgatacgccgcattctctgtagtcgac -gctctcaaatgggaaacaatctctattatttttttggaatcggatactatatcttcggta -tcttgacgcagtctagtatacatagagttaagagaaattagagtttgtacattaagcaac -atgtctctaaatgtggctacaaacttttctttttccacatcatctagtttattatatacc -gatttcacaacggcaccagatttaaggaaccagaatgaaaaactctgataactacaatat -ttcatcatagttacgattttatcatcttctatagttggtgtgataacacatacctttttc -tccaagactggaaccaacgtcataaaaatgtttaaatcaaaatccatatcaacatctgat -gcgctaagaccagtctcgcgttcaagattatctttactaatggtgacgaactcatcgtat -agaactctaagtttgtccattatttatttacagatttagttgtttaatttatttgtgctc -ttccagagttgggatagtatttttctaacgtcggtattatattattaggatctacgttca -tatgtatcataatattaatcatccacgttttgataaatctatctttagcttctgaaataa -cgtatttaaacaaaggagaaaaatatttagttacggcatcagacgcgataacattttttg -taaatgtaacgtatttagacgacagatcttcgttaaaaagttttccatctatgtagaatc -catcggttgttaacaccattcccgcgtcagagtgaataggagtttgaatagtttgttttg -gaaatagatccttcaataacttatagttgggtgggaaaaaatcgattttatcactagact -ctttcttttttactatcattacctcatgaactatttcttgaatgagtatatgtattttct -ttcctatatcggtcgcgttcattggaaaatatatcatgtcgttaactataagaatatttt -tatcctcgtttacaaactgaataatatcagatatagttcgtaaacgaactatatcatcac -cagcacaacatctaactatatgatatccactagtttcctttagccgtttattatcttgtt -ccatattagcagtcattccatcatttaagaaggcgtcaaagataatagggagaaatgaca -ttttggattctgttacgactttaccaaaattaaggatatacggacttactatctttttct -caacgtcgatttgatgaacacacgatgaaaatgtacttcgatgagattgatcatgtagaa -aacaacaagggatacaatatttccgcatatcatgaaatatattaagaaatcccactttat -tatatttccccaaaggatcaatgcatgtaaacattataccgttatcattaataaagactt -ctttctcatcggatctgtaaaagttgttactgatttttttcattccaggatctagataat -taataataatgggttttctattcttattctttgtattttgacatatcctagaccagtaaa -cagtttccactttggtaaaatcagaagacttttgaacgctattaaacatggcattaatgg -caataactaaaaatgtaaaatatttttctatgttaggaatatggtttttcactttaatag -atatatggttttttgccaaaatgatagatatttttttatccgatgatagtaaaatattat -tagtcgccgtctctataaaaatgaagctagtctcgatatccaattttattctagaattga -taggagtcgccaaatgtaccttatacgttatatctcccttgatgcgttccatttgtgtat -ctatatcggacacaagatctgtaaatagttttacgttattaatcatcacggtatcgccat -cgctagataatgctaatgtactatccaagtcccaaatggagagatttaactgttcatcgt -ttagaataaaatgattacctgtcatattaataaagtgttcatcgtatctagataacaacg -acttataattaatgtccaagtcttgaactcgctgaatgatcttttttaacccagttagtt -ttagattggtacgaaatatattgttaaactttgattctacagtaatgtccaaatctagtt -gtggaaatacttccatcaacattgtttcaaacttgataatattattatctacatcttcgt -acgatccaaattccggaatagatgtatcgcacgctctggccacccagataaccaaaaagt -cacacgctccagaatatacattgtataaaaagctatcgttttttagtagtgtttttttct -gagtatatacgaaaggattaaaaatagtattatcaacgtaactatattccaaattattct -tatgagaatagataataatatcgtccttaatatctaacaaatttcctaaatatcccttta -attgagtcattcgaagcgttaataaaatatgtctcttaactatttccggccgttgtatat -ttaaatgacttcgtaagaaataatatataggcgacttctcatctatgtaatcatatggag -tgagatatagggctcgttctacctcctgccccttacccacctgtaataccaattgcggac -tcactatatatcgcatatttatatcgtggggtaaagtgaaaatctactaccgatgatgta -agtcttacaatgttcgaaccagtaccagatcttaatttggaggcctccgtagaactaggg -gaggtaaatatagatcaaacaacacctatgataaaggagaatagcggttttatatcccgt -agtagacgtctattcgcccatagatctaaggatgatgagagaaaactagcactacgattc -tttttacaaagactttattttttagatcatagagagattcattatttgttcagatgcgtc -gacgctgtaaaagacgtcactattaccaaaaaaaataacattatcgtggcgccttatata -gcacttttaactatcgcatcaaaaggatgcaaacttacagaaacaatgattgaagcattc -tttccagaactatataatgaacatagtaagaaattcaaattcaactctcaagtatccatc -atccaagaaaaactcggataccagtctggaaactatcacgtttatgattttgaaccgtat -tactctacagtagctctggctattcgagatgaacattcatctggcatttttaatatccgt -caagagagttatcttgtaagttcattatctgaaataacatatagattttatctaattaat -ctaaaatctgatcttgttcaatggagtgctagtacgggcgctgtaattaatcaaatggta -aatactgtattgattacagtgtatgaaaaattacaactggccatagaaaatgattcacaa -tttacatgttcattggctgtggaatcagaacttccaataaaattacttaaagatagaaat -gaattatttacaaaattcattaacgagttaaaaaagaccagttcattcaagataagcaaa -cgtgataaggatacgctattaaaacattttacttatgactggagttagaatttatagacg -acacatttcgtttatcattgttactattactatcattattagtattcttcttgtcatctt -gttcagaaatatacagcaatgctatacctaatactaaatacattatcatgcttgcaatgg -ctctaacaacaacgaaccaaaatgaatttggtcgtagcttttgttcacaaaaatacataa -agaaatgtctacataaatctatggcgccattggctacttgaaatagcgccagtcctccta -cagattttaatatagctgtataacatgacatttattcatcatcaaaagagacagagtcac -catctgtcatatttagattttttttcatgtgttcaaagtatcctctactcatttcattat -aatagtttatcatgcttagaattttaggacggatcaatgagtaagacttgactagatcgt -cagtagtaatttgtgcatcatctattctgcatccgcttcgtcgaataatgtatagcatcg -ctttgagattctccatagctatcaagtctttatataatgacatggaaatatctgtgaatg -ctttatacttctccaacatcgatgccttaacatcatcacatactttagcattgaaaatac -gttctattgtgtagatggatgtagcaagatttttaaacaacaatgccatcttacatgatg -attgtctcaagtctccaatcgtttgtttagaacgattagctacagagtccaatgcttggc -taactagcatattattatctttagaaattgtattcttcaatgaggcgtttatcatatctg -tgatttcgttagtcatattacagtctgactgggttgtaatgttatccaacatatcaccta -tggatacggtacacgtaccagcatttgtaataatcctatctaagatgttgtatggcattg -cgcagaaaatatcttctcctgtaatatctccactctcgataaatctactcagattattct -taaatgccttattctctggagaaaagatatcagtgtccatcatttcattaatagtatacg -cagaaaagataccacgagtatcaattctatccaagatacttatcggttccgagtcacaga -taattgtttcctctccttcgggagatcctgcatagaaatatctaggacaatagtttctat -actgtctgtaactctgataatctctaaagtcactaactgataccatgaaattgagaagat -caaacgctgaagtaatcaatttttctgcctcgtttttactacaactagttttcatcaatg -tagtgacgatgtattgtttagttactcttggtctaatactgatgatagagatattattgc -ttcccataatggatcttctagtagtcaccttaaagcccattgatgcgaatagcagataga -taaagtcttggtatgactcctttctaatatagtacggactacctttgtcacccaacttta -tacccacataagccataacaacctctttaatagccgtttcatgaggtttatcagccatga -gcctgagtagttgaaagaatcgcatgaatcccgtctcagaaagtcctatatgcatgatag -atttatctttcctgggaaactctcgtatagttatagatgaaatactcttcaaagtttctg -aaataagattagtaacagtcttacctccgactactctgggtaacaaacatactctaatag -gtgttttctctgcggagataatatcagaaaggatagagcaataagtagtattattgtgat -tataaagaccgaatacataacaggtagaatttataaacatcatgtcctgaagggttttag -acttgtattcctcgtaatctataccgtcccaaaacatggatttggtaactttgatagccg -tagatctttgttccttcgctaacaggttaaagaaattaataaagaatttgttgtttctat -ttatgtccacaaattgcacgtttggaagcgccacggttacattcactgcagcattttgag -gatcgcgagtatgaagtacgatgttattgtttactggtatatctggaaagaaatctacca -gtctaggaataagagattgatatcgcatagaaatagtaaagtttataatctcatcattga -agattactctgttaccattgtaataaattggtactctatcataatcatcgacaaagtact -gttcatacatgatgagatgtttatatgttggcatagtagtgagatcgacgtttggtaatg -gcaatgtattaagattaactccataatgtctagcagcatctgcgatgttataagtgatgt -caaagcggggttgatcttgtgctgttatatattgtctaacacctataagattatcaaaat -cttgtctgcttaatacaccgttaacaatttttgccttgaattcttttattggtgcattaa -taacatccttatagaggatgttaaacaaataagtattatcaaagttaagatctgggtatt -tcttttctgctagaacatccattgagtcggagccatctggtttaatataaccaccgataa -atctagctctgtattctgtatccgtcaatctaatattaagaaggtgttgagtgaaaggtg -gaagatcgtaaaagctgtgagtattaataatagggttagtttccgaactaatgttaattg -gatgattaataatatttatatttccagcgttaagtgtaacattaaacagttttaattcac -gtgacgtggtatcaattaaataattaatgcccaatttggatatagtagcctgaagctcat -cttgtttagttacggatcctaatgagttattaagaaatacatcgaacggatgaacgaagg -ttgttttaagttggtcacatactttgtaatctagacatagatgtggaagaacggtagaaa -ctatacgaaatagatattcagagtcctctaattgatcaagagtaactattgacttaatag -gcatcatttatttagtattaaatgacgaccgtaccagtgacagatatacaaaacgactta -attacagagttttcagaagataattatccatctaacaaaaattatgaaataactcttcgc -caaatgtctattctaactcacgttaacaacgtggtagatagagaacataatgccgccgta -gtgtcatctccagaggaaatatcatcacaacttaatgaagatctatttccagatgatgat -tcaccggccactattatcgaacgagtacaacctcatactactattattgacgatacgcca -cctcctacttttcgtagagagttattgatatcggaacaacgtcaacaacgagaaaaaaga -tttaatattacagtatcaaaaaattctgaagcaataatggaatctagatctatgataact -tctatgccaacacaaacaccatccttgggagtagtttatgataaagataaaagaattcag -atgctagaggatgaagtggttaatcttagaaatcaacgatctaatacaaaatcatctgat -aatttagataattttaccagaatactatttggtaagactccgtataaatcaaccgaagtt -aataagcgtatagccatcgttaattatgcaaatttgaacgggtcccccttatcagtcgag -gacttggatgtctgttcggaggatgaaatagatagaatctataaaacgattaaacaatat -cacgaaagtagaaaacgaaaaattatcgtcactaacgtgattattattgtcataaacatt -attgagcaggcattgctaaaactcggatttgaagaaatcaaaggactgagtaccgatatc -acttcagaaattatcgatgtggagatcggagatgactgcgatgctgtagcatcaaaacta -ggaatcggtaacagtccggttcttaatattgtattgtttatactcaagatattcgttaaa -cgaattaaaattatttaatttaatacattcccatatccagacaacaatcgtctggattaa -tctgttcctgtcgtctcataccggacgacatattaatctttttattagtgggcatctttt -tagatggtttctttttcccagcattaactgattcgatacctagaagatcgtgattgattt -ctccgaccattccacgaacttctaattggccgtctctaacggtaccataaactattttac -cagcattagtaacagcttggacaatctgaccatccattgcgttgaatgatgtagttgctg -ttgttctacgtctaggagcaccagaggtatttttagagctcttggatgttgatgtagaag -acgaggattttgattttggtttacatgtaatacattttgaactctttgattttgtatcac -atgcaccggcagtcacatctgtttgagaattaagattattgttgcctcctttgacggctg -catctccaccgatctgcgctagtagatttttaagctgtggtgtaatcttattaactgttt -caatataatcatcgtaactacttctaacggctaaattttttttatccgccatttagaagc -taaaaatatttttatttatgcagaagatttaactagattatacaatgaactaatatgatc -cttttctagattatttacgaacttggtatttcttgtttctggaggaggagaatttaaatt -cggacttggattcggattttgtgggttcttgatcttattatacagcgtgtataggatggt -gacggtaactgctacacaaataccgatcaacagaagaataccaatcatttattgacaata -acttcactatgatcaagtatgtaataatcatcttttcactaagtaagtagtaataatgat -tcaacaatgacacgatatatggacgataataatttagttcatggaaatatcgctatgatt -ggtgtgaatgactccgctaactctgtggggtgcacagtgctttccccacatagaataaat -tagcattccgactgtgataataataccaagtataaacgccataatactcaatactttcca -tgtacgagtgggactggtagacttactaaagtcaataaaggcgaagatacacgaaagaat -caaaagaatgattccagcgattagcacgccagaaaaataatttccaatcataagcatcat -gtccatttaactaataaaaattttaaatcgccgaataaacaaagtggaatataaaccata -taaaaacaatagtttgtactgcaaaaataatatctatttttgttttcgaagatatggtaa -aattaaatagtagtacacagcatgttataactaacagcagcaacggctcgtaattactta -tcatttactagacgaaaaggtggtgggatattttcttgctcaaataatacgaatatatca -cccatccattttatacgatgtttatatactctaatctttaatagatctatagatgacggg -tttaccaataatatagattttatcgattcatctaatttaaacccttccttaaacgtgaat -gatctattatctggcataatgatgaccctacctgatgaatctgacaatgtactgggccat -gtagaataaattatcaacgaattatcgtctacgaacatttatatcatttgttttaatttt -aggacgtgaataaatagatataaaatagaaaataacagatattacaaccagtgttatgga -cgcacccaaccatgtaggcagttttattttatcgtttactacaggttctcctggatgtac -gtcaccaactgcagacgtagttctagtacaattagacgtaagttccgcttgggaattttt -taacgctaaagagttaacgttgatcgtacacccaacgtatttacatctagttctttgaac -atcttgattataatataaccattttctatctctagattcgtcagtgcactcatgtaacca -acataccctaggtcctaaatatttatctccggaattagattttggataattcgcgcacca -acaatttctatttcctttatggtcgttacaaaagacgtataatgccgtatccccaaaagt -aaaataatcaggacgaataattctaataaactcagaacaatatctcgcatccatatgttt -ggagcaaatatcggaataagtagacatagccggtttccgttttacacgtaaccattctaa -acaattggggtttccaggatcgtttctacaaaaaccagtcatgaaatcgtcacaatgttc -tgtcttgtaattattattaaatatttttggacagtgtttggtatttgtcttagaacaaca -ttttgccacgctatcactatcacccaggagataatccttttttataaaatgacatcgttg -cccggatgctatataatcagtagcatattttaaatccttaatatattcaggagttacctc -gttctgataatagattaatgatccaggacgaaatttgaaagaactacatggttctccatg -aattaatacatattgtttagcaaattcaggaactataaaactactacaatgatctatcga -cataccatctatcaaacaaaatttgggtttaatttctcctggagacgtttcataataata -catataactttcttcggcaaacctaacagctctattatattcaggataattaaaatctaa -taccatatatttgtctcgtatatctgctattcctgtctctattttgattctattaagagt -aacagctgcccccattcttaataatcatcagtatttaaactgttaaatgttggtatatca -acatctatcttatttcccgcagtataaggtttgttgcaggtatactgttcaggaatgggt -acatttatacttcttttatagtcctgtctttcgatgttcatcacaaatgcaaagaacaga -ataaacaaaataatgtaagaaataatattaaatatctgtgaattcgtaaatacattgatt -gccataataattacagcagctacaatacacacaatagacattcccacagtgttgccatta -cctccacgatacatttgagttactaagcaataggtaataactaagctagtaagaggcaat -agaaaagatgagataaatatcatcaatatagagattagaggagggctatatagagccaag -acgaacaaaatcaaaccgagtaacgttctaacatcattatttttgaagattcccaaataa -tcattcattattcctccataatcgttttgcatcatacccccatctttaggcataaacgat -tgctgctgttcctctgtaaataaatctttatcaagcactccagcacccgcagagaagtca -tcaagcatattgtaatatcttaaataactcatttatatattaaaaaatgtcactattaaa -gatggagtataatctttatgccgaactaaaaaaaatgacttgtggtcagaccataagtct -ttttaatgaagacggcgatttcgtagaagttgaaccaggatcatcctttaagtttctaat -acctaagggattttactcctctccttgtgtaaagacgagtctagtattcaagacattaac -aacgaccgataataaaattactagtatcaatccaacaaatgcgccaaagttatatcctct -tcaacgcaaagtcgtatctgaagtagtttctaatatgaggaaaatgatcgaattaaaacg -tcctctatacatcactcttcacttggcatgtggatttggtaagactattaccacgtgtta -tcttatgaccacacacggcagaaaaaccatcatttgcgtacccaataaaatgttaataca -tcaatggaagacacaggtagaggcagtcggattggaacataagatatctatagatggagt -tagtagtctattaaaggaactaaagactcaaagtccggatgtattaatcgtagtcagtag -acatctgacaaacgatgcattttgtaaatatatcaataagcattatgatttgtttatctt -ggatgaatcacatacgtataatctgatgaacaatacagcagttacaagatttttagcgta -ttatcctccgatgatgtgttattttttaactgctacacctagaccagctaaccaaattta -ttgtaatagtattattaatattgccaagttatccgatctaaaaaaaactatctatatagt -agatagtttttttgagccatattccacagacaatattagaaatatggtaaaacgactaga -tggaccatctaataaatatcatatatataccgagaagttattatctgtagacgagcctag -aaaccaacttattcttgataccctggtagaagaattcaagtcaggaactattaatagaat -tttagttattactaaactacgtgaacatatggtattcttctacaaacgattattagatct -tttcggagcagaggttgtatttataggagacgcccaaaatagacgtactccagatatggt -caaatcgattaaggaactaaatagatttatattcgtatccaccttattttattccggcac -tggtttagatattccgagtttggattctttgttcatttgctcggcagtaatcaacaatat -gcaaatagagcaattactagggagggtatgtcgagaaacagaactattagataggacggt -atatgtatttcctaacacatccatcaaaaaaataaagtacatgataggaaatttcgtgca -acgaattattagtctgtctgtagataaactcggatttaaacaagaaagttatcagaaaca -tcaggaatctgaacccgcttccgtaccaacatcctccagagaagaacgtgtattaaatag -aatatttaactcgcaaaatcgttaagaagtttaagagacgatccacatgctgagcaggcc -agtgtattacccctcatagtattaatataatccaatgatacttttgtgatgtcggaaatc -ttaaccaatttagactgacaggcagaacacgtcatacaatcatcatcgtcatcgataact -gtagtcttgggcttctttttgcgactcttcattccggaacgcatattggtgctatccatt -taggtagtaaaaaataagtcagaatatgccctataacacgatcgtgcaaaacctggtata -tcgtctctatctttatcacaatatagtgtatcaacatctttattattgacctcgtttatc -ttggaacatggaatgggaacatttttgttaacggccacctttgccttaattccagatgtt -gtaaaattataactaaacagtctatcatcgacacaaatgaaattcttgtttagacgtttg -tagtttacgtatgcggctcgttctcgtctcattttttcagatattgcaggtactataata -ttaaaaataagaatgaaataacataggattaaaaataaagttatcatgacttctagtgct -gatttaactaacttaaaagaattacttagtctgtacaaaagtttgagattttcagattct -gtggctatagagaagtataattctttggtagaatggggaacatctacttactggaaaata -ggcgtacaaaaggtaactaatgtcgagacgtccatatctgattattatgatgaggtaaaa -aataaaccgtttaatattgatccggggtattatattttcttaccagtatattttggaagc -gtctttatttattcaaagggtaaaaatatggtagaacttggatctggaaactcttttcaa -ataccggatgagattcgaagtgcgtgtaacaaagtattagatagtgataacggaatagac -tttctgagatttgttttgttaaacaatagatggataatggaagacgctatatcaaaatac -cagtctccagttaatatatttaaactagctagtgagtacggattaaacatacccaactat -ttagaaattgaaatagaggaagacacattatttgacgatgagttatactctattatggaa -cgctctttcgatgatacatttccaaaaatatctatatcgtatattaagttgggagaactt -aagcggcaagttgtagactttttcaaattctcattcatgtatattgagtcaatcaaggta -gatcgtataggagataatatttttattcctagcgttataacaaaatcaggaaaaaagata -ttagtaaaagatgtagaccatttaatacgatccaaggttagagaacatacatttgtaaaa -gtaaaaaagaaaaacacattttccattttatacgactatgatgggaacggaacagaaact -agaggagaagtaataaaacgaattatagacactataggacgagactattatgttaatgga -aagtatttctctaaggttggtattgcaggcttaaagcaattgactaataaattagatatt -aatgagtgtgcaactgtcgatgagttagttgatgagattaataaatccggaactgtaaaa -cgaaaaataaaaaaccaatcagtatttgatttaagcagagaatgtttgggatatccagaa -gcggattttataacgttagttaataacatgcggttcaaaatagaaaattgtaaggttgta -aatttcaatattgaaaatactaattgtttaaataacccgagtattgaaactatatatgga -aacttcaaccagttcgtctcaatctttaataccgttaccgatgtcaaaaaaagattattc -gagtgaaataatatgcgcctttgatataggtgcaaaaaatcctgccagaactgttttaga -agtcaaggataactccgttagggtattggatatatcaaaattagactggagttctgattg -ggaaaggcgcatagctcaagatttgtcacaatatgaatacactacagttcttctagaacg -tcagcctagaaggtcaccgtacgtcaaatttatctattttattaaaggctttttatatca -tacatctgctgccaaagttatttgcgtctcacctgtcatgtctggtaattcatatagaga -tcgaaaaaagagatctgttgaagcatttcttgattggatggacacattcggattgcgaga -ctccgttccggatagacgcaaattagacgatgtagcggatagtttcaatttggctatgag -atacgtattagataaatggaatactaattatacaccttataataggtgtaaatatagaaa -ttacataaaaaaaatgtaataacgttagtaacgccattatggataatctatttacctttc -tacatgaaatagaagatagatatgccagaactatttttaactttcatctaataagttgtg -atgaaataggagatatatatggtcttatgaaagaacgcatttcctcagaggatatgtttg -acaatatagtatataataaagatatacatcctgccattaagaaactagtttattgcgaca -tccaacttactaaacatattattaatcagaatacgtatccggtatttaacgattcttcac -aagtgaaatgttgtcattatttcgatataaactcaaataatagcaatattagctctcgta -cagtagagatatttgagagtgaaaagtcatctcttgtatcatatattaaaactaccaata -agaagagaaaggtcaattacggcgaaataaagaaaactgtacatggaggcactaatgcaa -attacttttccggtaaaaagtctgatgagtatctgagcactacagtcaggtccaacatta -atcaaccttggatcaaaaccatttctaagagaatgagagtagatatcattaatcactcta -tagtaacgcgtggaaaaagctctatattacaaactatagaaattatttttactaatagaa -catgtgtgaaaatattcaaggattctactatgcacattattctatccaaggacaaggatg -aaaagggatgtataaacatgattgataaattattctatgtatattataatttatttctgt -tgttcgaggatatcatccaaaacgattactttaaagaagtagctaatgttgtaaaccatg -tactcatggctacggcattagatgagaaattattcctaattaagaaaatggctgaacacg -atgtttatggagttagcaatttcaaaatagggatgtttaacctgacatttattaagttgt -tggatcataccgttttcccctctctgttagatgaggatagcaaaataaagttttttaagg -ggaaaaagctcaatattgtagcattacgatctctggaggattgtacaaattacgtgacta -aatccgagaatatgatagaaatgatgaaggaaagatcgactattttaaatagcatagata -tagaaacggaatcggtagatcgtctaaaagaattgcttctaaaatgaaaaaaaacactga -ttcagaaatggatcaacgactcgggtataagtttttggtgcctgatcctaaagccggagt -tttttatagaccgttacatttccaatatgtatcgtattctaattttatattgcatcgatt -gcatgaaatcttgaccgtcaagcggccactcttatcgtttaagaataatacagaacgaat -tatgatagaaattagcaatgttaaagtgactcctccagattactcacctataattgcgag -tattaaaggtaagagttatgacgcattagccacgttcactgtaaatatctttaaagaggt -aatgaccaaagagggtatatccatcactaaaataagtagttatgagggaaaagattctca -tttgataaaaattccgctactaataggatatgggaataaaaatccacttgatacagccaa -gtatcttgttcctaatgtcataggtggagtctttatcaataaacaatctgtcgaaaaagt -aggaattaatctagtagaaaagattacaacatggccaaaatttagggttgttaagccaaa -ctcattcactttctcgttttcctccgtatcccctcctaatgtattaccgacaagatatcg -ccattacaagatatctctggatatatcacaattggaagcgtcgaatatatcatcgacaaa -gacatttataacggtcaatattgttttgctgtctcaatatttatctagagtgagtctaga -attcattagacgtagtttatcatacgatatgcctccagaagttgtctatctagtaaacgc -gataatagatagtgctaaacgacttaccgaatctattactgactttaatattgatacata -cattaatgacctggtggaagctgaacacattaaacaaaaatctcagttaacgattaacga -gtttaaatatgaaatgctgcataactttttacctcatatgaactatacacccgatcaact -aaagggattttatatgatatctttactaagaaagtttctctactgtatctaccacacttc -tagatatccagatagagattcgatggtttgtcatcgcatcctaacgtacggcaaatattt -tgagacgttagcacatgatgaattagagaattacataggtaacatccgaaacgatatcat -gaacaatcacaagaacagaggcacttacgcagtaaacattcatgtactaacaactcctgg -acttaatcatgcattttctagtctattgagtggaaagttcaaaaagtcagacggtagtta -tcgaacacatcctcactattcatggatgcagaatatttctattcctagaagtgttggatt -ttatccggatcaagtaaagatttcaaagatgttttctgtcagaaaataccatccaagcca -atatctttacttttgttcatcagacgttccggaaagaggtcctcaggtaggtttagtatc -tcaattgtctgtcttgagttccattacaaatatactaacgtctgagtatttggatttgga -aaagaaaatttgtgagtatatcagatcatattataaagatgatataagttactttgaaac -aggatttccaatcactatagaaaatgctctagtcgcatctcttaatccaaatatgatatg -tgattttgtaactgactttagacgtagaaaacggatgggattcttcggtaacttggaggt -aggtattactttagttagggatcacatgaatgaaattcgcattaatattggagcaggaag -attagtcagaccattcttggttgtggataacggagagctcatgatggatgtgtgtccgga -gttagaaagcagattagacgacatgacattctctgacattcagaaagagtttccacatgt -catcgaaatggtagatatagaacaatttacttttagtaacgtatgtgaatcggttcaaaa -atttagaatgatgtcaaaggatgaaagaaagcaatacgatttatgtgactttcctgccga -atttagagatggatatgtagcatcttcactagtgggaatcaatcacaattctggacccag -agctattcttggatgtgctcaagctaaacaagctatctcttgtctgagttcggatatacg -aaataaaatagacaatggaattcatttgatgtatccagagaggccaattgtgattagtaa -ggctttagaaacttcaaagattgcggctaattgcttcggacaacatgttactatagcatt -aatgtcgtacaaaggtatcaatcaagaggatggaattatcatcaaaaaacaatttattca -gagaggcggtctcgatattgttacagccaagaaacatcaagtagaaattccattggaaaa -ctttaataacaaagaaagagataggtctaacgcctattcgaaattagaaagtaatggatt -agttagactgaatgctttcttggaatccggagacgctatggcaagaaatatctcatcaag -aactcttgaagatgattttgctagagataatcagattagctttgatgtttccgagaaata -tacagatatgtacaaatctcgcgttgaacgagtacaagtagaacttactgacaaagttaa -ggtgcgagtattaaccatgaaagaaagaagacccattctaggagacaaatttactactag -aacgagtcaaaagggaacagtcgcgtatatcgcagatgaaacggaacttccgtacgacga -aaatggtatcacaccagatgtcattattaattctacatccatcttctctagaaaaactat -atctatgttgatagaagttattttaacagccgcatattctactaagccgtacaacaataa -gggagaaaaccgacctgtctgttttcctagtagtaacgaaacatctatcgatgcatatat -gcaattcgctaaacaatgttatgagtattcaaatccgaaattgtccgaggaagaattatc -ggataaaatcttttgtgaaaagattctctatgatcctgaaacggataagccttatgaatc -caaagtattttttggaccaatttattacttgcgtctgagacatttaactcaggacaaggc -aaccgttagatgtagaggtaaaaagacgaagctcattagacaagcgaatgagggacgaaa -acgtggaggaggtatcaagtttggagaaatggagagagactgtttaatagcacatggtgc -agccaatactattacagaagttttaaaagactcagaagaggattatcaagatgtgtatat -ttgtgaaaattgtggagacatagcagcacaaatcaaaagtattaatacatgtcttagatg -ttcaaaacttaatctctctcctctcttaacaaaaattgataccacgcacgtatctaaagt -atttcttactcaaatgaacgccagaggcgtaaaagttaaattagatttcgaacgaaggcc -tccttcgttttataaaccattagataaagttgatcttaaaccgtcttttctggtataata -ttgtttagtagatactcatcaagataagctaattcactaaacatattatcggattcggta -ttgttactcgagaatagagttcgttatgctcctgatattcggaaatctgtggagtttcag -gttttggtggaagtgtaactgctacttggtgggatactgaaggatatttcagagagttgt -ggatgttcgggttcgacatccaccgatggtgtcacgccactaatcggttcggtaacgtct -gtggatggaggtgctacttctacagaacctgtagcctcagttgtcaacggagatacatat -tcaatgcgcggaaatgtataatttggtaatggtttctcatgtggatcttaagaagaagag -gtaagatatctacgaaagataccgatcacgtttctagttctcttttgtagaactttaact -ttttctttctcagcatctagttgatattccgacctcttcacgtttcgcatgggttacctc -cgcagtttttacaagcgatttcacgttccagatcacgttcagccttcatacgtctctccc -tctctctatcgagtttatcagagcagtctttctgaaggcgatcgaactccataaatttct -ccaacgctttgattgtttccatagatttccgaagtttagcttctaggacggcgattcttt -ttttttttttttttttttttttcgaattcacggggtacaaccgtttccattaccaccatc -tctatgtttcttttctagatcggcaatctttctcaatctttctcaacatttcatccccat -accttttcattcctcgagtctattgtcgtcgaaatatcgttccagctccttttcgacctc -aataactttagcacgttgtttcatcaagctctctcttgtagtactatcatttttatctga -ttccctgacacgtttaagatcttcatgtaattgagtcagctcttgacgcaatctcttaac -taacttcctctcttgcttcttcgtcatagtacttacaatcactatgggatccattgttac -cacgtctgtactcgacgagctcacgtttaagagattcaatttccagtttgtatcggtcca -tgtctccattgctacaccaccattagatttacaggctgctagttgtcgttcgagatcaga -aatacgtgttttcttggaatggatttcgtcgatgtacttgtcatgattggcatcgaaaca -cttattaagttctttttttcaattctacgattttatttctttcgcgagtcaattccctcc -tgtagtaactatcagttttgtcagattcacgctctctacgtagactttcttgtaagttac -taatttgttccctggcattaccgagttcagttttatatgccgaatagagttctgattcat -cctttgagaagatctctagcgatcgttcaagatccctgattctagtctttagcctattta -cctcctcagaagatgctccgttaccgtttttacaatcgttaagatgtctatcaagatcca -tgattctatctcttttccatatcagcattgatttcattattacgttcgcagtcgttcaac -tgtatttcaagatctgagattctagattgtaatctctgtagcatttccacggcattcact -cagttgtctttcaagatctgagattctagattggagtctgctaatctctgtaagatttcc -tcctccgctctcgatgcagtcggtcaacttattctctagttctctaatacgcgaacgcag -tgcatcaacttcttgtgtgtcttcttgattgcgtgtgcattcatcgagtctagattcgag -atctctaacgtgacgtcgttcttcctcaagttctctgtgtactacagaaagcgtgtccct -atcttgttgatatttagcaatttctgattctagagtactgattctactcacgtatgtact -aatagttgtcttagccttatcaagatcctccttgtatttgtcacattccttgatatccat -acgaagtctggacagttcccattcgacattacgacgtttatcgatttcagctcggagatc -gtcgtcgcgttgttttagccacatacgactaagttcaagttctcgttgacaagatccatc -tacttttccatccctaatagtatccagttccttttctagttctgaccgcatttctcgttc -catatcaagagattctctcaattctcgtatagtcttcttatcaatttctgatgaatctga -accatcatctgtcccattttgttgcatatccctgagttctttgatctctgttgtaagtct -gtcgattctttcggttttataaacagaatccctttccaaagtcctaatcttactgagttt -atcattaagttcttcattcaattcagtgagttttctcttggcttcttccaagtctgtttt -aaactctccatcatttccgcattcttcctcgcatttatctaaccattcaattagtttatt -aataactagttggtaatcagcgattcctatagccgttcttgtatttgtgggaacataatt -aggatcttctaatggattgtatggcttgatagcatcatctttatcattattaggtggggg -atggacaaccttaattggttggtcctccttatctcctccagtagcatgtggttcttcaat -accagtattagtaataggcttagacaaatgcttgtcgtacgcgggcacttcctcatccat -caagtatttataatcgggttctgtttcagaatattcttttctaagagacgcgacttcagg -agttagtagaagaactctgtttctgtatctatcaacgctggaatcgatactcaagttaag -gatagcgaatacctcatcgtcatcatccgtatcttctgaaacgccatcatatgacatttc -atgaagtctaacgtattgataaacagaatcagatttagtattaaacagatccttgacctt -tttagtaaatgcatatgtatattttagatctccagatttcataatatgatcgcatgcctt -aaatgtcaatgcttccatgatatagtctggaacactaatgggtgacgaaaaagatacagc -accatatgctacgttgataaatagatctgaaccactaagtagataatgattaatgttaag -gaagaggaaatattcagtatatagatatgccttagcatcatatcttgtactaaacacgct -aaacagtttattgatgtgatcaatttccaacagaacaattagagcggcaggaataccaac -aaacatattaccacatccgtattttctatgaatatcacatatcatattaaaaaatcttga -tagaagagcgaatatctcgtctgacttaatgagatgtagttcagcagcataagtcataac -tgtaaatagaacatactttcctgtagtgttgattctagactccacatcaacaccattatt -aaaaatagttttatatacatctttaatctgctctccgttaatcgtcgaacgttctagtat -acggaaacactttgatttcttatctgtagttaatgacttagtgatatcacgaagaatatt -acgaattacatttcttgtttttcttgagagacctgattcagaactcaactcatcgttcca -tagtttttctacctcagtggcgaaatctttggagtgtttggtacattttttaataaggtt -cgtgacctccatttattataaaaaatttttattcaaaacttaactacaatcgggtaatta -taagatcgtagatctcccatgtggtggaatactaccatctatcgcatgttgatggacagt -aggtaatggccatgggaacagtaatgtttgcatatttatctttcttgctagtattactgt -atattgtcccaatgtttcaatgtgatgttctaacctatcaactgccactgtatcacaaca -ataatgtccgatggaattaagattatgatccaatgtgtttaatatatgattatcaagtct -tatacgatccgcgtcttttttgacaggatcaggctcttctacaggaagaagtttcggcct -cttatgatagtcatgtctgggaaatggtggtctaggatgaggatcaggtatcggagtagg -ttttggattataatcatcatcatcatcatcatcatcatcatcatcatcatcatctatgat -atcatcatcttcgatatttattttgctatcttgataatgtcctatatcagttgcattttc -agcactcgactgaatattagtacattcattgtctattattaacgtatttctaaacccaaa -atgtatatgttgaacatcactactatagttgatgagtcttatagcatgaattcgcttatc -gttatcgggtttatcttctgtcaccttaacaattccttttttattaaactctgcataatc -ataaccatttctattgtttgttctaatataaacgagtatagcatcattgctaaatttttc -aatagtatcaaaaacagaatatcctaaaccatataatatatattcaggaacactcaaact -aaatgtccaggattctcctaaatacgtaaactttaatagtgctaaatcattcaaaaatct -accgcttatagatagatagtacatgaatgcgtatagtagtctacctatctctttattatg -aaaaccgacattacgatcatatatttcgtgatatacatgtgacccgtttacgttaaacca -taaatacatgggtgatcctataaacatgaatttatttctaattctcagagccatagttaa -ttgaccgtgtaatatttgtttacatgcatacttgatacgatcattaataagatttttatc -attgctcgttatttcagaatcgtatatataaggagtaccatcatgattcttaccagatat -tatacaaaatactatatataaaatatattgacccacgttagtaatcatgtaaatgtttaa -tgttttaaattttgtatttaatgatccatcatcatatgctagcatggtcttgtgatattc -attctttaaaatataatattgtgttagccattgcattggagctcctaatggagattttct -attctcgtccattttaggatatgctttcataaagtccctaataacttcgtgaataatgtt -tctatgttttctactgatgcatgtatttgcttcgatttttttatcccatgtttcatctat -catagatttaaacgcagtaatgctcgcaacattaacatcttgaaccattggtacaattcc -gttccataaatttataatgttcgccatttatataactcattttttgaatatacttttaat -tgaacaaaagagttaagttactcatatggatgccgtccagtctgtacatcaatcttttta -gccagagatatcatagccgctcttagagtttcagcgtgattttccaacctaaatagaact -tcatcgttgcgtttacaacacttttctatttgttcaaactttgttgttatattagtaatc -tttttttccaaattagttagccgttgtttgagagtttcctcattatcgtctccataggct -ttaacaattgcttcgcgtttagtctctggatttttagcagcctttgtagagaaaaattca -gttgctggaattgcaagatcgtcatctccggggaaaagagttccgtccatttaaagtaca -gattttagaaactgacactctgtgttatttatatttggcgcaatacatggattataaata -tcgatgttaataacatcagaaaatgtaaagtctatacattgtcgcatcgtgttaaatttt -ctaatggatctagtattattgggtccaacttctgcctgaaatccaaatatggaagcggat -acaaaaccgtttcctggataaaccacacatctccacttttgctttacatcagaaattgtg -tcattgacatcttgaactctcctatctaatgccggtgttccacctatagattttgaatac -tcgaatgctgcatgagtagcattgaattccttaatattgccataattttcatatattgag -taactctggataaaaagtaaacacaccgcagccgtcgctactacaataaaaaaaattgat -agagagttcatttataatctattagaagctgataaaatttttttacacgcgtcagacaat -gctttaataaatagttcaacatctacttttgtcatatcgaaccgatggtatgattctaac -ctagaattacatccgaaaaagttgactatgttcatagtcattaagtcattaacgaacaac -attccagactctggattataagacgatactgtttcgtcacaatcacccaccttaatcatg -tgattatgaatattggctattagagtaccttctaagaaatctataatatctttgaaacac -gatttaaaatcaaaccacgaatatacttctacgaagaaagttagtttacccataggagag -ataactataaatggagatctagatacaaaatccggatctatgatagttttaacattatta -tattctctattaaatacctccacatctaaaaatgttaattttgaaactatgtcttcgttt -attaccgtacctgaactaaacgctataagctctattgtttgagaactctttaaacgatat -tcttgaaatacatgtaacaaagtttcctttaactcggtcggtttatctaccatagttaca -gaatttgtatccttatctataatataataatcaaaatcgtataaagttatataattatcg -tgttcagattgtgatcttttcaaatagactaaaaaccccatttctctagtaagtatctta -tgtatatgtttgtaaaatatcttcatggtgggaatatgctctacagcagttagccattcc -tcattgacagctgtagatgtattatacaaaactactccaatgtttaacaagggccatttt -acgagattattaaatccttgtttgataaatgtagccaatgcgggttcgagttcaacgacg -attgaattctcttcccgtggatgctgcatgatgaacgacgggatgttgttgttctattga -tttggaattctttttcgactttttgtttatattaaatattttaaaatttatggctgatag -taattcatgtactacggataatgtagacgtgtattgcatatcgatatctttattattaga -taaatttatcaataaatgtgagaagtttgcctcgttaaggtcttccatttaaatattata -taaatatttgtgtttgtattttattcgtcttttatgggatagtttttaactagtaaagct -gtaattacatactttgtccgtaaaacataaatataaatacccgcttttatcaaacgttcc -aaaaagtcggcagctgacatttttaacatgacatctattttaaatacacttaggttttta -gaaaaaacatcattttataattgtaacgattcaataactaaagaaaagattaagattaaa -cataagggaatgttatttgtattttataagccaaagcattctaccgttgttaaatacttg -tctggaggaggtatatatcatgatgatttggttgtattggggaaggtaacaattaatgat -ctaaagatgatgctattttacatggatttatcatatcatggagtgacaagtagtggagca -atttacaaattgggatcgtctatcgatagactttctctaaataggactattgttacaaaa -gttaataacaattataacaattataacaattataacaattataattgttataataattat -aattgttataattatgatgatacattttttgacgatgatgattgatcactattacacaat -tttgtttttgtactttctaatatagtgtttaggttctttttcatatgagaatattgactt -actaaaatatctatgtttaacttttgttctataacgtccttatcggcggtatcggtacat -atacgtaattcaccttcacaaaatacggagtcttcgataataatagccaatcgattattg -gatctagctgtctgtatcatattcaacatgtttaatatatcctttcgtttcccctttaca -ggcatcgatcgtagcatattttccgcgtctgagatggaaatgttaaaactgcaaaaatgc -gtaatgttagcccgtcctaatattggtacgtgtctataagtttggcatagtagaataata -gacgtgtttaaatgccttccaaagtttaagaattctattagagtattacattttgatagt -ttatcacctacatcatcaaaaataagtaaaaagtgtgctgattttttatgattttgtgcg -acagcaatacatttttctatgttacttttagttcgtatcagattatattctagagcttcc -tgactactaacgaaattaatatgatttggccaaatgtatccatcataatctgggttataa -acgggtgtaaacaagaatatatgtttatattttttaactagtgtagaaaacagagatagt -aaatagatagtttttccagatccagatcctcctgttaaaaccattctaaacggcattttt -aataaattttctcttgaaaattgtttttcttgaaaacaattcataattatatttacagtt -actaaattaatttgataataaatcaaaatatggaaaactaaggtcgttagtagggaggag -aacaacgaaggcatatcgtgatataaataacatttattatcatgatgacaccagaaaacg -acgaagagcagacatctgtgttctccgctactgtttacggagacaaaattcagggaaaga -ataaacgcaaacgcgtgattggtctatgtattagaatatctatggttatttcactactat -ctatgattaccatgtccgcgtttctcatagtgcgcctaaatcaatgcatgtctgctaaca -aggctgctattactgactccgctgttgccgttgctgcggcatcatctactcatagaaagg -ttgtgtctagcactacacaatatgatcacaaagaaagctgtaatggtttatattaccagg -gttcttgttatatattacattcagactataagtcattcgaggatgctaaagcaaactgcg -ctgcggaatcatcaacactacccaataaatccgatgtcttgactacctggctcattgatt -atgttgaggatacatggggatctgatggtaatccaattacaaaaactacatccgattatc -aagattctgatgtatcacaagaagttagaaagtatttttgtacataaataaatgaaatcg -cttaatagacaaactgtaagtaggtttaggaagttgtcggtgccggccgctataatgatg -ttactctcaaccattattagcggcataggaacatttctgcattacagagaagaactgatg -cctagtgcttgcgccaatggatggatacaatacgataaacattgttatctggataccaac -attaaaatgtctacggataatgcagtttatcagtgtcgcaaattacgagctagattgcct -agacctgatactagacatctgagagtattgtttagtattttttataaagattattgggta -agtttaaaaaagaccaatgataaatggttagatattaataatgataaagatatagatatt -agtaaattaacaaattttaagcaactaaacagcacgacggattctgaggcgtgttatata -tacaagtctggaaaactggttaaaacagtatgtaaaagtactcaatctgtactatgcgtt -aaaagattctacaagtgacaacaaaaaatgaattaatagtaagtcgttaacgtacgccgc -catggacgccgcgtttgttattactccaatgggtgtgttgactataacagatacattgta -tgatgatctcgatatctcaatcatggactttataggaccatacattataggtaacataaa -aattgtccaaatagatgtacgggatataaaatattccgacatgcaaaaatgctactttag -ctataagggtaaaatagttcctcaggattctaatgatttggctagattcaacatttatag -tatttgtacagcatacagatcaaaaaataccatcatcatagcatgcgactatgatatcat -gttagatatagaaggtaaacatcaaccattttatctattcccatctattgatgtttttaa -cgctacaatcatagaagcgtataatctgtatacagctggagattatcatctgatcatcaa -tccttcagataatctgaaaatgaaattgtcgtttaattcttcattttgtatatcagacgg -caatggatggattataattgatgggaaatgtaatagtaattttttatcataaaagttgta -aagtaaataataaaacaataaatattgaactagtagtatgttgtatattgagcaatcaga -gatgatgctggtacctcttatcacggtgaccgtagttgcgggaacaatattagtatgtta -tatattatatatttgtaggaaaaagatacgtactgtctataatgacaataaaattatcat -gacaaaattaaaaaagataaagagtcctaattccagcaaatctagtaaatcaactgatag -cgaatcagactgggaggatcactgtagtgctatggaacaaaacaatgacgtagataatat -ttctagaaatgagatattgaacgatgatagcttcgctggtagtttaatatgggataacga -atccaatatcatggcgcctagcacagaacacatttacgatagtgttgctggaagcacgct -gctaataaataatgatcgtaatgaacagactatttatcagaatactacagtagtaattaa -tgatacagagactgttgaaatacttaatgaagataccaaacagattcctagctattcttc -caatcctttcgtaaattataataaaaccagtatttgtagcaagtcaaatccgttcattgc -agaactcaacaataaatttagtgataataatccgtttaggagagcacatagtgacgatta -tcttaataagcaacaagatcatgaatacgatgatatagaatcatcggttgtatcattggt -ctgattagtttcctttttataaaattgaagtaatatttagtattaattaccgccgatgca -ttatacaaatatggagatattccctgtattcggcatttctaaaattagcaattttattgc -taataatgactgtagatattatatagatgtagagcatcaaaaaattatatctgatgagat -caatagacagatggatgaaacggtacttcttaccaacatcttaagcgtagaagttgtaaa -tgacaatgagatgtaccatcttattccccatagactatcgactattatactctgtattag -ttctgttggaggatgtgttatctctatagataatgacgtcaatgacaaaaatattctaac -atttcccattgatcatgctgtaatcatatccccactgagtaaatgtgtcgtagttagcaa -gggccctacaaccatactggttgttaaagcggatatacccagcaaacgattggtaacatc -gtttacaaacgacatactgtatgtaaacaatctatcactgattaattatttaccgtcgtc -tgtattcattattagacgagtcaccgactatttggatagacacatatgtgatcagatatt -tgctaataataagtggtattccattataactatcgacgataagcaatatcctattccatc -aaattgtataggtatgtcttctgccaagtacataaattcgagcatcgagcaagatatttt -gatccatgtttgtaacctcgagcatccattcgactcagtctacaaaaaaatgcagtcgta -caattctctacctatcaaggaacaaatattgtatggtagaattgataatataaatatgag -cattagtatttcggtggattaatagatttctctagtatgggatcattaatcatctctaaa -tacatcataaaaaagctattatcaaatactgtactgaatggattcattcttttctctttt -tatgaaactctgttgtatatctacggataaaactagaagcaaaaaatctgataggaagaa -taatgattatatggaggaacacgattattataaaataacaatagttcctggttcctcttc -cacgtctactagctcgtggtattatacacatgcctagtaatagtctctttgcgttgacgg -aaagcagactagaaataacaggccaaaatgttcagacaccataatagttcccaacccaga -taataacagagttccatcaacacattcctttaaactcaatcccaaacccaaaaccgttaa -aatgtatccagccaattgatagtagataatgaggtgtacagcacatgataatttacacag -taaccaaaatgaaaacactttagtaattataagaaatatagacggtaatgtcatcatcaa -caatccaataatatgcctgagagtaaacattgacggataaaacaaaaatgccccgcataa -ctctatcatggcaataacgcaaccaaacacttgtaaaattcctaaattagtagaaaatac -aactgatatcgatgtataagcgatttcgaggaataataagaacaaagtaattcccgtaaa -gataaacatcaacattgtttggtaatcattaaaccaattagtatgacgttgaattaattt -cacagtatattttattccagtattatccccgcatgtatacgtacctggtaagatatcttt -atattccataatcaatgagacatcactatccgataacgaatgaagtctagcactagtatg -ccatttacttaatatggtcgtcttggaagttttattataagttaaaatatcatgattgtc -caatttccatctaatatactttgtcggattatctataatacacggaataatgatggtatc -attacatgctgtatattctatagtctttgtagatgttataaccacaaaagtacagaggta -tatcaacaatattctaactcttaacatttttatttatttaaaatgatacctttgttattt -attttattcttattttgctaacggtatcgaatggcataagtttgaaacgagtgaagaaat -aatttctacttacttaatagattatgtggtaacgggtgttattaatggggatgtatatac -attttcaaataatgaactaaacaaaactgggttaactaataacaataattatatcacaac -atctataaaagtagaggataaggatacattagtagtatgcggaaccaataacggaaatcc -caaatgttggaaaatagacggttcatactacccaaaacatataggtagaggatacgatca -tcaaaatagcaaagtaacgataatcagtcacaatgaatgtgtactatccgacataaacat -ataaaaagaaggaattaaacgatggagaagatttgacggaccatgtggttatgattaaac -gagttaagttttttaagaagccttagaagagaggctattgggtatgagaatccgaaatat -taaaccagacaaccccatataattttatagctaagaatgccgcgaagaatggaactaata -aaaacggaaatatttgtagcacaacgaataactcccaaactgcattcatgttacactata -taacactacttcggttagatgttttagaaaaaataaatatcaccgtaccgttttgttgta -taaaaataacaattaacaattatcaatttttttctttaatattttacgtggttgaccatt -cttggtggtaaaataatctcttagtgttggaatggaatgctgtttaatgtttccacactc -atcgtatattttgacgtatgcagtcacatcgtttacgcaatagtcagactgtagttctat -catgcttcctacgttagaaggaggaacagttttaaagtctcttggttttaatctattgtc -attagttttcatgaaatcctttgttttatccacttcacattttaaataaatgtccactat -acattcttctgttaattttactagatcatcatgagtcatagaattcataggttccgtagt -ccatggatccaaactagcaaacttcgcgtatacggtatcgcgattagtgtatacaccaac -tgtatgaaaattaagaaaacagtttaataaatctacagaaatatttaatcctccgtttga -tacagatgcgccatatttatggatttcggattcacacgttgtttgtctaaggggttcgtc -tagtgttgcttctacatagacttcgattcccatatattctttattgccagaatcacatac -cgatttatcatacgctggttcacttgtttgaaaactaaatggtagtagatacatcaaaat -aataaataataagtacattctgcaatattgttatcgtaattggaaaattggtattcaagt -gagctggattatgtgagtattggattgtatattttattttatattttatattttatattt -tattttatattttatattttattttatattttgtagtaagaatagaatgctaatgtcaag -tttattcgaatagatgtcttattaaaaaacatatataataaataacaatggctgaatggc -ataaaattatcgaggatatctcaaaaaataataagttcgaggatgccgccatcgttgatt -acaagactacaaagaatgttctagcggctattcctaacagaacatttgcaaagattaatc -cgggtgaagttattcccctcatcactaatcataatattctaaaacctcttattggtcaga -aattttgtattgtatatactaactctctaatggatgagaacacgtatgctatggagttgc -ttactgggtacgcccctgtatctccgatcgttatagcgagaactcataccgcacttatat -ttttgatgggtaagccaacaacatccagacgtgatgtgtatagaacatgtagagatcacg -ctacccgtgtacgtgcaactggtaattaaaataaaaagtaatattcatatgtagtgtcaa -ttttaaatgatgatgaaatggataatatccatattgacgatgtcaataatgccggtattg -acatacagctcatcgatttttagatttcattcagaggatattgaattatgttatgggaat -ttgtattttgataggatctataataatgtagtaaatataaaatatattcctgagcatatt -ccatatagatataattttattaatcgtacgttctccgtagatgaactagatgataatgtc -ttttttacacatggttattttttaaaacacaaatatggttgttcacttaatcctagtttg -attgtctcattatcaggaaacttaaaatataatgatatacaatgctcagtaaatgtatcg -tgtctcattaaaaatttggcaacgagtacatctactatattaacatctaaacataagact -tattctctatatcggtccatgtgtattgctataataggatacgattctattatatggtat -aaatatataaatgacaggtataatgacatctatgattttactgcaatatgtatgctaata -gcgtctacattgatagtgatcatatacgtgtttaaaaaaataaaaatgaactcttaatta -tgttatactattagaaatggataaaatcaaaattacgattgattcaaaaattggtaatgt -tgttaccatatcgtataacttggaaaagataactattgatgtcacgccaaaaaagaaaaa -agaaaaggatgtattattagcgcaatcagttgctgtcgaagaggcaaaagatgtcaaggt -ggaagaaaaaaatattatcgatattgaagatgacgatgatatggatatagaaaacacgta -atacgatctataaaaataagtattaaatactttttatttacggtactcttgtagtggtga -taccactaatcgattattttttttaaaaaaatacttattctgattcttctagccatttcc -gtgttcgttcgaatgccacatcgacgtcaaaaataggggagtagttgaaatctagttctg -cattgttggtacgcacctcaaatgtagtgttggatatcttcaacgtatagttgttgagta -ttgatggttttctaaatagaattctcttcatatcattcttgcacgcgtacatttttagca -tccatcttggaatcctagatccttgttctattcccaatggtttcatcaatagaagattaa -acatatcgtaagaacacgatggagagtaatcgtagcaaaagtaagcatttcctttaatcg -cagatcccggatactggatatattttgcagccaacacgtgcatccatgcaacatttccta -catatacccggctatgcacagcgtcatcatcgactgtacgatacataatgttaccgtgtt -gcttacattgctcgtaaaagactttcgtcaatttgtctccttctccgtaaattccagtgg -gtcttaggcaacaagtatacaattttgcgccattcatgattacggaattattggctttca -taaccagttgctcggccatacgtttactttttgcgtatacatgtcctggtgatatatcat -aaagggtatgctcatgaccgatgaatggattaccgtgtttatttggtcctattgcttcca -tgctactagtatagatcaaatacttgattcctaggtccacacaagctgccaatatagtct -gtgttccataatagtttactttcatgatttcattatcagtgtattttccaaatacatcca -ctagagcagccgtatgaataatcagatttaccccatctagcgcttctctcaccttatcaa -agtcgtttatatcacattgtatatagtttataaccttaactttcgaggttattggttgtg -gatcttctacaatatctatgactcttatttcttgaacatcatctgcgctaattaaaagtt -ttactatatacctgcctagaaatccggcaccgccagtaaccgcgtacacggccattgctg -ccactcataatatcagactacttattctattttactaaataatggctgtttgtataatag -accacgataatatcagaggagttatttacgttgaacaagtccatggaaaagataaagttt -taggatcagttattggattaaaatccggaacgtatagtttgataattcatcgttacggag -atattagtcgaggatgtgattccataggcagtccagaaatatttatcggtaacatctttg -taaacagatatggtgtagcatatgtttatttagatacagatgtaaatatatctacaatta -ttggaaaggcgttatctatttcaaaaaatgatcagagattagcgtgtggagttattggta -tttcgtacataaatgaaaagataatacattttcttacaattaacgagaatggcgtttgat -atatcagttaatgcgtctaaaacaataaatgcattagtttacttttctactcagcaagat -aaattagtcatacgtaatgaagttaatgatatacactacactgtcgaatttgatagggac -aaagtagttgatacgtttatttcatataatagacataatgactccatagagataagaggg -gtgcttccagaggaaactaatattggtcgcgtggttaatacgccggttagtatgacttac -ttgtataataagtatagttttaaaccgattttagcagaatatataagacacagaaatact -atatccggcaacatttattcggcattgatgacgctagatgatttggttattaaacagtat -ggagacattgatctattatttaatgagaaacttaaagtagactccgattcgggactattt -gactttgtcaactttgtaaaggatatgatatgttgtgattctagaatagtagtagctcta -tctagtctagtatctaaacattgggaattgacaaataaaaagtataggtgtatggcatta -gccgaacatatagctgatagtattccaatatctgagctatctagactacgatacaatcta -tgtaagtatctacgcggacacactgatagcatagaggatgaatttgattattttgaagac -gatgatttgtctacatgttctgccgtaaccgatagggaaacggatgtataatttttttta -tagtatgaaggatatgatggatatgatgatatgatggatatgatgatatgatggatatga -tggatatgatggatatgatggatatgataaaaaaatataattgttgtatccattcccatt -caaatcaccttatatgattctgtaacacaatgaaggagtctcatagatatatagaggtca -gatactggtttgataaactttttattccacatgagcatgtttgacttatggttagacaca -catactttaacaaatcactgaaaattggagttaggtattcctctcagaatcagttgccgt -tctggaacattaaatgtattttttatgatatactccaacgcatttatgtgggtatacaac -aagtcattaataatgagtatttccaagagttttagttgtctagtatttaacaagagaaga -gatttcaacagactgtttatgaactcgaataccgcctcattgtcgcttatattgatgaca -tgacatcgaattcccaatatcaatctcatcagtgatgagtagctcaatcttgttatcggg -atccaatttctaaagatgtcattaaaccctcgatcgtgaatggatttatcatcatcgttt -ttatgttggacatgagcttagtccgtttgtccacatctatatacgatgatttctgaatta -tttcatatatctctcgttaactccaggaacttgtcagggatctaactttaatatgttctc -gtctaagagatgaaaatctttggatggttgcatgtgacttttctctaaaggatgatgtta -cccgatcctctcttaaatgactccatcttatccttggacaagatggacagtctattttcc -ttagatggtttaatattttttacccatgatctataaaggtagacagacctaatcgtctcg -gatgaccatatattattttccgttttattatacgcataaattgtaaaaaatatgttaggt -ttacgaaaatgtctcgtggggcattaatcgtttttgaaggattggacaaatctggaaaaa -caacacaatgtatgaacatcatggaatctataccggcaaacacgataaaatatcttaact -ttcctcagcgatccacagtcactggaaagatgatagatgactatctaactcgtaaaaaaa -cctataatgatcatatagttaatctattattttgtgcaaatagatgggagtttgcatctt -ttatacaagaacaactagaacagggaattactttaatagttgacagatacgcgttctctg -gagtagcgtatgccaccgctaaaggcgcgtcaatgactctcagtaagagttatgaatctg -gattgcctaaacccgacttagttatattcttggaatctggtagcaaagaaattaatagaa -acatcggcgaggaaatttatgaagatgttgaattccaacaaaaggtattacaagaatata -aaaaaatgattgaagaaggagatattcattggcaaattatttcttctgaattcgaggaag -atgtaaagaaggagttgattaagaatatagttatagaggctatacacacggttactggac -cagtggggcaactgtggatgtaataaaatgaaattacatttttataaatagatgttagta -cagtgttataaatggatgaagcatattactctggcaacttggaatcagtactcggggata -cgtgtccgatatgcataccgaactcgcatcaatatctcaattagttattgccaagataga -aactatagataatgattattaaacaaggacattgtaaattttatcatgtgtagatcaaac -ttggataatccatttatctctttcctagatactgcatatactatcatagatcaagagatc -tatcagaacgagttgattaattcattagacgataatgaaattatcgattgtatagttaac -aagtttatgagcttttataaggataacctagaaaatatggtagatgctatcattactcta -aaatattataattaataatccagattttaaaactacgtatgtggaagtactcggttccag -aatagctgatatagatattaaacaagtgatacgtaagaatataatacaattgtctaatga -tccgcgaacgatatttgtgaaaatattaaaaaaaaatactttttttattaaatgacgtct -cttcgcgaatttagaaaattatgctgtgatatatatcacgcatcaggatataaagaaaaa -tctaaattaattagagactttataacagatagagatgataccgatacatatttgatcatt -aagctattgcttcccggattagacgatagaatgtataacatgaacgataaacaaattata -aaattatatagtataatatttaaacaatctcaggaagatatgctacaagatttaggatac -ggatatataggagacactattaggactttcttcaaagagaacacggaaatccgtccacga -gataaaagcattttaactttagaagaagtggatagttttttaactacgttatcatcagta -actaaagaatcacatcaaataaaattattgactgatatagcatctgtttgtacatgtaat -gatttaaaatgtgtagtcatgcttattgataaagatctaaaaattaaagcgggtcctcgg -tacgtgcttaacgctattagtcctcatgcctatgatgtttttagaaaatctaataacttg -aaagagataatagaaaatgcagctaaacaaaatctagactctatatctatttctgttatg -actccaattaatcccatgttagcggaatcatgtgattctgtcaataaggcgtttaaaaaa -tttccatcaggaatgtttgcggaagtcaaatacgatggtgaaagagtacaagttcataaa -aaaaataacgagtttgcattctttagtagaaacatgaaaccagtactctctcataaagtg -gattatctcaaagaatacataccgaaagcatttaaaaaagctacgtctatcgtattggat -tctgaaattgttcttgtagacgaacataatgtaccgctaccgtttggaagtttaggtata -cacaaaaagaaagaatataaaaactctaacatgtgtttgttcgtatttgactgtttatac -tttgatggattcgatatgacagacattccattgtatgaacgaagatcttttctcaaagat -gttatggtcgaaatacccaatagaatagtattctcagagttgacgaatattagtaacgag -tctcagttaactgatgtattagatgatgcactaacgagaaaattagaaggattggtctta -aaagatattaatggcgtatacgaaccgggaaagagaagatggttaaaaataaagcgagac -tatttgaacgagggttccatggcagattctgccgatttagtagtactaggtgcctactat -ggtaaaggaggaaagggtggtatcatggcagtctttctaatgggttgttacgacgatgaa -tccggtaaatggaagacggtaactaaatgttccggtcacgatgataatacgttaagggtt -ttgcaagaccaattaacgatggttaaaattaacaaggatcccaaaaaaattccagagtgg -ttggtagttaataaaatctatattcccgattttgtagtagatgatccgaaacaatctcag -atatgggaaatttcaggagcagagtttacatcttccaagtcacatacagcgaatggaata -tcgattagatttcctagatttactaggattagagaagataaaacgtggaaagaatctact -catctaaacgatttagtaaacttgactaaatctcttaatagttacatataaactgaaaaa -taaaataacactattttagttggtagtcgccatggatggtgttatcgtatactgtctaaa -tgcgttagtaaaacatggcgaggaaataaatcatataaaaaatgatttcatgattaaacc -atgttgtgaaagagtttgtgaaaaagtcaagaacgttcacatcggcggacaatctaaaaa -caatacagtgattgcagatttgccatatctggataatgctgtatcagatgtatgcaaatc -aatatataaaaagaatgtatcaagaatatccagatttgctaatttgataaaaatagatga -cgatgacaagactcctaccggcgtatataattattttaaacctaaagatgctattcctgt -tattatatccataggaaaggataaagatgtctgtgaactattaatctcatctgataaagc -gtgtgcgtgtataaagttaaatttatataaagtagccattcttcccatggatgtttcctt -ttttaccaaaggaaatgcatcattgattattctcctgtttgatttctctatcgatgcggc -acctctcttaagaagtgtaaccgataataatgttattatatctagacaccagcgcctaca -tgacgagcttccgagttccaattggttcaagttttacataagtataaagtccgactattg -ttctatattatatatggttgttgatggatctatgatgtatgcgatagctgataatagaac -tcacgcaattattagcaaaaatatattagacaatactacgattaacgatgagtgtagatg -ctgttattctgaaccacagattaggattcttgatagagatgagatgctcaatggatcatc -gtgttatatgaacagacattgtattatgatgaatttacctgatgtaggcgaatttggatc -tagtatgttggggaaatatgaacctgacatgattaagattgctctttcggtggctggtaa -tttaataagaaatcgagactacattcccgggagacgaggctatagctactacgtttacgg -tatagcctctagataattttttttaagcacgaaataaaaacataattttaaacaatctat -ttcatactattttgtgtgctcaccatgaacataaagatagatatattagtatttctggtg -ataaatttacggcgactgctaggagggaaaatgaagaaagaaaaaatatctacctctcca -aaaagaaaaactactgatgttatcaaacctgattatcttgagtacaatgacttgttagat -agagatgagatgtctactattctagaggaatattaggccttagaataaaatatggacgac -tcttaacgaaattagaaaattcgataatgatgttgaagaacaattcggtactatagaaga -actcaagcagaagcttagattaaattctgaagagagagcagataattttatagattatat -aaaggtacaaaaacaggatatcatcaaacttactgtatacgattgcatatatctatgata -ggattgtgtgcgtgcgtggtagatgtttggagaaatgagaaactgttttctagatggaaa -tattggttacaagcgattaaactgtttattgatgatcacatgcttgataagataaaatct -attgtagaatagactagtgtatgtggaaatgtcatagaaagttaaaagttaatgagagca -aaaatatataaggttgtattccatatttgttatttttttctgtaatagttagaaaataca -ttcgatggtctatctaccagattattatgtgttataaggtacttttctcataataaacta -gagtatgagtaagatagtgtttttcaaaaacatataaatctaaaattgatggatgagata -tacagctattaatttcgaaaatatattttaatctgataactttaaacatggatttttgat -ggtggtttaagtttaaaaaagattttgttattgtagtatgataatatcaaaaagatggat -ataaagaatttactgactacatgtactattttacattactacattggctacggcatatat -acctatttcgtcacttccacacgctccggtaaacgggtgtcatgtgacgagggagaatct -tgataagaggcataatcaatgttgtaatccgatgtccacctggagaatttgccaaggtca -gatgtagagttggtagtgataacacaaaatgtgaacactgcccacctcatacatataccg -caatccccaattattctaatagatgtcatcaatgtagaaaatgcccaacaggatcatttg -ataaggtaaagtgtaccggaacacagaacaaatgttcgtgtcatcctggttggtatacgc -tactgattcttcacagactgaagattgtcgagatttgtgtaccaaaaaaggagatgtcca -tgcggatactttggtggaatagatgaaggaaatcctatttgtaaatcgtgttgtgttggt -gaatattgcgactacctacgtaattatagacttgatccatttcctccatgcaaactatct -atctaaatgtaattaattatgattttgatgataatgttaccatacattatatcactactt -ggttagtgtgtattatttagtatggaagacctattaataattacttatcttttgacgatc -ttgttataattataatataaaaatacttatgacatagtaactcataattgctgacgcgat -aaattcgtaataatctgttttgttcaaatttttataaggaatctacaggcataaaaataa -aaatataatctataatatactcttacaacgccatcatgaatagcagtgaattaattgctg -ttattatggatttagaaatagtggacgattttgtgatattaatatagttattaatgatga -aaggataaacgcgcatagactcatcctatctggagcctccgaatattttttccattctgt -tttccaataattttatcgattctaatgaatacgaagttaatctaagtcatttagattatc -aaagtgttaactatttgatcgattacatttatgggatacctttgagcctaactaacaata -acgtgaaatatattctttcaaccgctgatttttttacaaattggatctgtcattactgag -tgcgaaaaatacatacttaaaaatctttgttttagaaactgtatcgatttctacatatac -gctgataaatataataacaagaaaatagaattagcatcgtttaacacaatattacgaaat -attttgagactcatcaacaatgaaaactttaaatacttaacagaggaatcaatgataaaa -attttaagcgatgatatgttatatataaaaaatgaggatttcaccccactgattctcatt -aaatggttagagagtacaccaaccatgtaccgtcgagttacttagatgcctcagaatatc -atttctttccccacaagttataaaatcactttatagtcatcgactggttagttcaatcta -cgaatgtataacattcttaaacaatatagcattcttggataaatcatttcctagatacca -tatcatcgagttgatatctatcggtataagtaattcacatgataagatttccataaactg -ctacaatcataaaaaaattcatgggaaatgatatcttcacgtagatataggtgtagtttc -gcagtgaccgtcctggataatattatctatatgatgggtggatatgatcagtccctgtat -agaagttcaaaggttatagcgtacaatacatgtactaattcttggatatatgatatacca -gagctaaaaatatcatcgttctaattgcggaggagttgccaatgacgaatacatttattg -tataggcggtatacgcgatcaggagtcatcgttgatatctagtatcgatagatggaagcc -atcaaaaccatattggcagaagtatgctaaaatgtgcgaaccaaaatgtgatatggggtt -gcgattttaaacggattaatatatgtcataggtggagtcgttaaaggtgacacacatata -ccaacgcactagagagtttatcagaagatggatggatgaatcatcaacgtcttccaataa -aaatgtccaatatgtcgacgattgttcatgctggaaagatttatatatctagaggttaca -acaatagtagtgtagttaatgtaatatcgaatctagtccttagctataatccgatatatg -atgaatggaccaaattatcatcattaaatattcctagaattaatcctgctctatggtcag -tgtataataaattatatgtaggaggagtaatatctgatgatgttcaaactaatacatctg -aaacatacgataaagaaaaagattgttggacattggataatggtcacttgttaccacata -attatataatgtataaatgcgaaccgtttaaacatagatatccattggaaaaaacacagt -acacgaatgattttctaaagtatttggaaagttttataggtagttgatagaacaaaatac -ataattttgtaaaaataaatcactttttatactaatatgacacaattaccaatacttttg -ttactaatatcattagtatacgctacaccttctcctcagacatctaaaaaaataggtgat -gatgcaactatatcatgtagtcgaaataatacaaattactacgttgttatgagtgcttgg -tataaggagcccaattccattattctcttagctgccaaaagcgacgtcttgtattttgat -aattataccaaggataaaatatcttacgactctccatacgatgatctagttacaactatc -acaattaaatcattgactgctggagatgccggtacttatatatgtgcattctttatgaca -tcgactacaaatgatactgataaagtagattatgaagaatactccatagagttgattgta -aatacagatagtgaatcgactatagacataatactatctggatctacaccagaaactatt -tctgagaaaccagaggatatagataattctaattgctcgtctgtattcgaaatcacgact -ccggaaccaattactgataatgtagacgaccatacagacaccgtcacatacactagtgat -agcattaatacagtaaatgcatcatctggagaatccacaacagacgagattccggaacca -attactgataaagaagaagatcatacagtaacagacactgtctcatacactacagtaagt -acatcatctggaattgtcactactaaatcaaccaccgatgatgcggatctttatgataca -tacaatgataatgatacagtaccgccaactactgtaggtggtagtacaacctctattagc -aattataaaaccaaggacttcgtagaaatatttggtattaccacattaattatattgtca -gcagtggcgattttctgtattacgtattatatatgtaataaacacccacgtaaatacaaa -acagagaacaaagtctagatttttgacttacataaatatctgggataataaaatctatca -tattgagaggaccatctggttcaggaaagacagccataaccaaaagactgttaaaagact -atgggaatatatttggatttgtggtgtcccataccactagatttcctcgtcctatggaac -gagaaggtgttgattaccttacgttaacagagaggccatctggaagggaatagccgccgg -aaactttctagaacatactgagtttttaggaaatatttacggaacttctaaaacagctgt -aaatacagcggttattaataatcgtatttgcgcgatggatttaaacatcaacggtgttag -aagtcttaaaaatacttacctaatgcattacttgggtatataagacctacctctcttaaa -atggttgagaccaatcttcgtcgtagaaacactgaagcggacgacgaatctcatcgtcgc -gtgatgttggcaaaaaacggatatggatgaggtcaacgaagcaggtctattcgacactat -tattattgaagatgatgtgaatttagcatatagtaagtgttaattcagatactacaggac -cgtattagaatgtattttaacactaattagagacttaagatttgacttaaaacttgataa -ttaataatataactcgtttttatatgtggctatttcaacgtctaatgtattagttaaata -ttaaaacttaccacgtaaaacttaaaatttaaaatggtatttcattgacagatcatacat -tatgaagtttcaaggacttgtgttaattgacaattgcaaaaatcaatgggtcgttggacc -attaataggaaaaggtggattcggtagtatttatactactaatgacaataattatgtagt -aaaaatagagcccaaagctaacggatcattatttaccgaacaggcattttatactagagt -acttaaaccatccgttatcgaagaatggaaaaaatctcacaatataaagcacgtaggtct -tatcacatgcaaggcatttggtttatacaaatccattaatgtggaatatcgattcttggt -aataaatagattaggtgcagatctagatgcggtgatcagagccaataataatagactacc -agaaaggtcggtgatgttgatcggaatcgaaatcttaaataccatacaatttatgcacga -gcaaggatattctcacggagatattaaagcgagtaatatagtcttggatcaaatagataa -gaataaattatatctagtggattacggattggtttctaaattcatgtctaacggcgaaca -tgttccatttataagaaatccaaataaaatggataacggtactctagaatttacacctat -agattcgcataaaggatacgttgtatctagacgtggtgatctagaaacacttggatattg -tatgattagatggttgggaggtatcttgccatggactaagatatctgaaacaaagaattc -tgcattagtaagtgccgcaaaacagaaatatgttaacaatactgcgactttgttaatgac -cagtttgcaatatgcacctagagaattgctgcaatatattaccatggtaaactctttgac -atattttgaggaacccaattacgacgagtttcgtcgagtattaatgaatggagttatgaa -aaatttttgttgataaaaaaattaaaaaaataacttagttattatcactctcgtgagtac -aatagaaacatggcgatgttttacgcacacgctttcggtgggtacgacgagaaccttcat -gcatttcctggaatatcatcgacggttgccaatgatgtcaggaaatattctgttgtgtca -gtttataataaaaagtataacattgtaaaaaacaaatatatgtggtgtaacagtcaagtg -aacaagagatatattggagcactactgcctatgtttgaatgcaatgaatatctacaaatt -ggagatccaatccatgatctagaaggaaatcaaatctctattgtcacatatcgccacaaa -aactactatgctctaagtggaattgggtacgagagtctagacttgtgtttggaaggagta -gggattcatcatcacgtacttgaaacaggaaacgcggtatatggaaaagttcaacatgag -tattctactatcaaagagaaggccaaagaaatgaatgcactcaaaccaggacctatcatc -gattaccacgtctggataggagattgtgtctgccaagttactactgtagacgtgcatgga -aaggaaattatgagaatgagattcaaaaggggtgcggtgcttccgattccaaatctggta -aaagttaaagttggggaggaaaatgatacaataaatctttccacttccatatcagctctc -ctaaattccggtggcggcaccatcgaggtaacatctaaggaagaacgtgtagattatgta -ctcatgaaacgtttggaatctatacatcatttgtggtctgtagtgtatgatcatcttaat -gttgtgaatggcgaagaacgatgttatgtacatatgcattcatctcatcaaagtcctatg -ctgagtactgtaaaaacaaatttgtacatgaagactatgggagcatgtcttcaaatggac -tccatggaagctctagagtatcttagtgaactgaaggaatcaggtgggcggagtcccaga -ccagaattgcagaaatttgaatatccagatggagtgaaagacactgaatcaattgagaga -ttggcagaggagttcttcaatagatcagaacttcaggccggtgaatcagtcaaatttggt -aattctattaatgttaaacatacatctgtttcagctaagcaactaagaacacgtatacga -cagcagcttccttctatactctcatcttttgccaacacaaagggtggatatttgttcatt -ggagttgataataatacacacaaagtaattggattcacggtgggtcatgactacctcaaa -ctggtagagagtgatatagaaaagtatatccaaaaacttcctgttgtgcatttctgcaag -aaaaaagaggacatcaagtacgcatgtagattcatcaaggtgtataaacctggtgatgag -actacctcgacatatgtgtgcgcaatcaaagtggaaagatgctgctgtgctgtgtttgcg -gattggccagaatcatggtacatggatactagtggtagtatgaagaagtattctccagat -gaatgggtgtcacatataaaattttaattagggtaaggtaaaactatatataataactaa -caatttgtgtatcatatagacaattaattaggtaactgttatctctttttaactaactaa -ctaactaactaactcttatatactattaataatacatctattaatcattgattagcttat -tgctttaattgtttttgtaaactaacactgttcattgaaaagggataacatgttacagaa -tataaattatatatggatttttttaaaaaggaaatacttgactggagtatatatttattt -cttcattacataacacgtctgtgttctaattcttccaattcttccacatctcatataata -caggaatataatcttgttcgaaaatatgagaaagtggataaaacaatagttgatttttta -tctaggtggccaaatttattccatattttagaatatggggaaaatattctacatatttat -tttatagatgctgctaatacgaatattatgattttttttctagatagagtattaaatatt -aataagaaccgtgggtcatttatacataatctcgggttatcatccattaatataaaagaa -tatgtatatcaattagttaataatgatcatctagataatagtataagactaatgcttgaa -aatggacgtagaacaagacattttttgtcttatatattggatacagttaatatctatata -agtattttaataaatcatagattttatatagatgccgaagacagttacggttgtacatta -ttacatagatgtatatataactataagaaatcagaatcagaatcatataatgaattaatt -aagatattgttaaataatggatcagatgtagataaaaaagatacgtacggaaacacaccg -tttatcctattatgtaaacacgatatcgacaacgcggaattgtttgagatatgtttagag -aatgctaatatagactctgtagactttaatggatatacacctcttcattatgtctcatgt -cgtaataaatatgattttgtaaagttattaatttctaaaggagcaaatgttaatgcacgt -aatagattcggaactactccattttattgtggaattatacacggtatctcgcttataaaa -ctatatttggaatcagacacagagttagaaatagataatgaacatatagttcgtcattta -ataatttttgatgctgttgaatctttagattatctattgtccagaggagttattgatatt -aactatcgtactatatacaacgaaacatctatttacgacgctgtcagttataatgcgtat -aatacgttagtctatctattaaacagaaatggtgattttgagacgattactactagtgga -tgtacatgtatttcggaagcagtcgcgaacaacaacaaaataataatggatatactattg -tctaaacgaccatctttgaaaattatgataccatctatgatagcaattactaaacataaa -caacataatgcagatttattgaaaatgtgtataaaatatactgcgtgtatgaccgattat -gatactcttatagatgtacaatcgctacatcaatataaatggtatattttaaaatgtttt -gatgaaatagatatcatgaagagatgttatataaaaaataaaactgtattccaattagtt -ttttgtatcaaagacattaatactttaatgagatacggtagacatccttctttcgtgaaa -tgtaatattcttgacgtatacggaagttgtgtacgtaatatcatagcatctattagatat -cgtcagagattaattagtctattatccaagaagctggatgctggagataaatggtcgtgt -tttcctaacgaaataaaatataaaatattggaaaactttaacgataacgaactgaccaca -tatctgaaaatcttataaacactattaaaatataaaatctaagtaggataaaatcacact -acatcattgtttccttttagtgctcgacagtgtatactatttttaacactcataaataaa -aatgaaaacgatttccgttgttacgttgttatgcgtactacctgctgttgtttattcaac -atgtactgtacccactatgaataacgctaaattaacgtctaccgaaacatcgtttaatga -taaacagaaagttacgtttacatgtgattcaggatatcattctttggatccaaatgctgt -ctgtgaaacagataaatggaaatacgaaaatccatgcaagaaaatgtgcacagtttctga -ttatgtctctgaactatatgataagccattatacgaagtgaattccaccatgacactaag -ttgcaacggtgaaacaaaatattttcgttgtgaagaaaaaaatggaaatacttcttggaa -tgatactgtcacgtgtcctaatgcggaatgtcaacctcttcaattagaacacggatcgtg -tcaaccagttaaagaaaaatactcatttggggaatatatgactatcaactgtgatgttgg -atatgaggttattggtgtttcgtatataagttgtacggctaattcttggaatgttattcc -atcatgtcaacaaaaatgtgatataccgtccctatctaatggattaatttccggatctac -attttctatcggtggcgttatacatcttagttgtaaaagtggttttacactaacggggtc -tccatcatccacatgtatcgacggtaaatggaatcccatactcccaacatgtgtacgatc -taacgaagaatttgatccagtggatgatggtcccgacgatgagacagatctgagcaaact -ctcgaaagacgttgtacaatatgaacaagaaatagaatcgttagaagcaacttatcatat -aatcataatggcgttgacaattatgggtgtcatatttctaatctccattatagtattagt -ttgttcctgtgacaaaaataatgaccaatataagttccataaattgctaccgtgaatata -aatccgttaaaataattaataattaataattaataacgaacaagtatcaaaagattaaag -aattagctagaatcaattagatgtcttcttcagtggatgttgatatctacgatgccgtta -gagcatttttactcaggcactattatgacaagagatttattgtgtatggaagaagtaaca -ccatattacataatatatacaggctatttacaagatgcaccgttataccgttcgatgata -tagtacgtactatgccaaatgaatcacgtgttaaacaatgggtgatggatacacttaatg -gtataatgatgaatgaattcgatactgtatgtgtgggtaccggactacgattcatggaaa -tgtttttcgattacaataaaaataatcccaaaaatagcatcaacaatcaaataatgtatg -atataattaatagcgtagccataattctagctaatgagagatatagaagcgcgtttaacg -acgatagaatatacatccgtagaactatgatggacaaattgtacgaatacgcatctctaa -ctactattggtacgatcactggaggtgtttgttattttatctgttgatgcatctagttag -tttgtataaataattatttcgatatactagttaaaattttaagattttaaatgtataaaa -aactaataacgtttttatttgtaataggtgcagttgcatcctattcgaataatgagtaca -ctccgtttaataaactgagtgtaaaactctatatagatggagtagataatatagaaaatt -catatactgatgataataatgaattggtgttaaattttaaagagtacacaatttctatta -ttacagagtcatgtgacgtcggatttgattccatagatatagatgttataaacgactata -aaattattgatatgtataccattgactcgtctactattcaacgcagaggacatacgtgta -gaatatctaccaaattatcatgccattatgataagtacccttatatccacaaatatgagg -gtgatgaacgacaatattctattaccgcagagggaaaatgctataaaggaataaaatatg -aaataagtatgatgaacgatgatactctattgagaaaacatactcttaaaattggattta -cttatatattcgatcgtcatgggcatagtaatacatattattcaaaatatgatttttaaa -aatttaaaatatattatcacttcagtgacagtagtcaaataacaaacaacaccatgagat -atattataattctcgcagttttgttcattaatagtatacatgctaaaataactagttata -agtttgaatccgtcaattttgattccaaaattgaatggactggggatggtctatacaata -tatcccttaaaaattatggcatcaagacgtggcaaacaatgtatacaaatgtaccagaag -gaacatacgacatatccggatttccaaagaatgatttcgtatctttctgggttaaatttg -aacaaggcgactataaagtggaagagtattgtacgggactatgtgtcgaagtaaaaattg -gaccaccaactgtaatattgactgaatatgacgatcatatcaatttgttcatcgagcatc -cgtatgctactagaggtagcaagaagattcctatttacaaacgcggtgacatgtgtgata -tctacttgttgtatacggctaacttcacattcggagattctgaagaaccagtaacatatg -atatcgatgactacgattgcacgtctacaggttgcagtatagactttgccacaacagaaa -aagtgtgtgtgacagcacagggagccacagaagggtttctcgaaaaaattactccatgga -gttcggaagtatgtctgacacctaaaaagaatgtatatacgtgcgcaattagatctaaag -aagatgttcccaatttcaaggacaaaatagccagagttatcacgagaaaatttaataaac -agtctcaatcttatttgactaaatttctcggtagcacatcgaatgatgttacaacttttt -ttagcattcttgactaaatattcataactaatttttattaatgatacaaaaatgaaataa -actgtatattatacactggttaacgcccttggctctaaccattttcaagatgaggtccct -gattatagtccttctgttcccctctatcatctactcaatgtctattagacgatgcgagaa -gactgaagaggaaacatggggattaaaaatagggttgtgtataattgccaaagatttcta -tcccgaaagaactgattgcagtgttcatcgcccaactgcaagtggaggattgataactga -aggcaatggattcagagtagttatatatgatcaatgtacagaaccccatgactttattat -caccgatactcaacaaacacgtcttggatcatctcatacatatattaaattcagtaacat -gaatacaggtgtcccatctagtattccaaaatgttccagaactctctgtatttctgtata -ttgtgatcaagaggcgggagacataaaatttgaggagtatactcaagaatcaagtgatat -cagtattagagttaagtatgattcatcatgtattgattatctgggtattaatcaaagttt -catgaatgaatgtattcgaagaattacaacatgggatagagaatcatgcgtcagaattga -tacacagactataaataaatatcttaagtcttgcaccaacacaaaattcgaccgtaatgt -ctacaaaaggtacatactgaagagtaaagcactccatgctaaaacagagttgtaatagat -ataaaatactttttataataattaggctagaaaaatctcactcacatgtaatcttaaaaa -aatgatatgatagttcttacaagtagcgattgagttttaaatggattctattaattaccg -gggaacttaacaattcgttctgatctacagacattggttaataaatcatcttattttgcc -aatatattaaaatgtggaaactccactaataatattacattgtgcgactttcaagatgat -gtgatatatagggttatacagttttaacaattatataatagagatagaaagtacaaaaga -tgtagaatcaatgatatggcacgctaaacagttgggtgtggaatcattgctaaaagaatg -tcaaaattatttgcttagaatattacgtatataattgtttagaaatttatagaataacta -atattaatacattatcgtatatctacaacgatataagaaacttcatattggataatatta -ctattaatatataaggatccagattttatatatttgcctaaatacattattatagattta -ctaggacaatcacctaaatgtttttaacgaagataatgtggtaaagattatatacactta -tatatcttccgatatctacaaggatattccatatcatcattgtgtaaactaaataacgtt -ttctatggcatttaataaggacattggatatgtggaaaagtgatgtatggaagttagtac -attatcaacttctccttattgattgaaaatgaaaatataaatagtttttatgtatagcgg -tatctaccctatagttttattgcttactactaacatggattcagatacagatacagatac -agatacagatacagatacagatacagatacagatgtagaagatatcatgaatgaaataga -tagagagaaagaagaaatactaaaaaatgtagaaattgaaaataataaaaacattaacaa -gaatcatcccagtgaatatattagagaagcacttgttattaataccagtagtaatagtga -ttccattgataaagaagttatagaatatatcagtcacgatgtaggaatatagatcatatc -tactaatttttataatcgatacaaaacataaaaacaactcgttattacatagcaggtatg -gaatccttcaagtattgttttgataacgatggtaagaaatggattatcggaaatacttta -tattctggtaattcaatactctataaggtcagaaaaaatttcactagttcgttctacaat -tacgtaatgaagatagatcataaatcacacaagccattgttgtccgaaatacgattctat -atatctgtattggatcctttgactatcaacaactggacacgagaacgtggtataaagtat -ttggctattccagatctgtatggaattggagaaaccgatgattatatgttcttcattata -aagaatttgggaagagtattcgccccaaaggatagtgaatcagttttcgaagcatgtgtc -actatgataaacacgttagagtttatacactctcaaggatttactcatggaaaaatagaa -ccgatgaatatactgattagaaataaacgtatttcactaattgactattctagaactaac -aaactatacaaaagtggaacacatatagattacaacgaggacatgataacttcaggaaat -atcaattatatgtgtgtagacaatcatcttggagcaacagtttcaagacgaggagattta -gaaatgttgggatattgcatgatagaatggttcggtggtaaacttccatggaaaaacgaa -agtagtataaaagtaataaaacaaaaaaaagaatataaacaatttatagctacttttttt -gaggactgttttcctgaaggaaatgaacctctggaattagttagatatatagaattagta -tacatgttagattattctcaaactcctaattatgacagactacgtagactgtttatacaa -gattgaaattatattcttttttttatagagtgtgggggtagtgttacggatatctaatat -taatattagactatctctatcgcgctacacgaccaatatcgattactatggatatcttca -gggaaatcgcatcttctatgaaaggaaagaatgtattcatttctccagcgtcaatctcgt -cagtattgacaatactgtattatggagctaatggatccactgctgaacagctatcaaaat -atgtagaaaaggaggagaacatggataaggttagcgctcagaatatctcattcaaatcca -tgaataaagtatatgggcgatattctgccgtgtttaaagattcctttttgggaaaaattg -gcgataagtttcaaactgttgacttcactgattgtcgcactatagatgcaatcaataagt -gtgtagatatctttactgagggaaaaatcaatccactattggatgaaccattgtctcctg -atacctgtctcctagcaattagtgccgtatactttaaagcaaaatggttgatgccattcg -aaaaggaatttaccagtgattatcccttttacgtatctccaacggaaatggtagatgtaa -gtatgatgtctatttacggcgagccatttaatcacgcatctgtaaaagaatcattcggta -acttttcaatcatagaactgccatatgttggagatactagtatgatggtcattcttccaa -acaagattgatggattagaatccatagaacaaaatctaacagatacaaattttaagaaat -ggtgtaactctctgaaagctacgtttatcgatgtgcacattcctaagtttaaggtaatag -gttcgtataatcttgtggatacgctaataaagttgggactgacagatgtgttctattcaa -ctggtgattatatcaatatgtgtaattcagatgtgagtgttgacgctatgattcacaaaa -cgtatatagatgtcaatgaagagtatacagaagcagctgcagcaacttctgtactagtgg -cagactgtgcatcaacagttacaaatgagttctgtgcagatcatccgttcatctatgtga -ttagacatgtcgatggtaaaattcttttcgttggtagatattgctctccaacaactaatt -aagcacattcttaatattagaatattatatagttaagatttttactaacaggttaacatt -tttttttaaaaatagaaaaaacatgtggtattagtgcaggtcgttattcttccaattgca -attggtaagatgacggccaactttagtacccacgtcttttcaccacaacactgtggatgt -gacagactgaccagtattgatgacgtcagacaatgtttgactgaatatatttattggtcg -tcgtatgcataccgcaacaggcaatgcgctggacaactgtatgacacactcctctctttt -aaagatgatgcggaatcagtgttcatcgacgttcgtgagctggtaaaaaatatgccgtgg -gataatgttaaggattgtacagagatcatccgttgttatataccggatgagcaaaaaacc -atcagagagatttcggccatcattggactttgtgcatatgctgctacttactggggaggt -gaagaccatcccactagtaacagtctgaacgcattgtttgtgatgcttgagatgctcaat -tacatggattataccatcatattctggcgtatgaattgatgagttacagcttgacatttc -ttctttcctccctcttcttctacctttcccagaaacaaactttttttacccactataaaa -taaaatgagtatactacctgttatatttcttcctatatttttttattctccattcgttca -gacttttaacgtgcctgaatgtatcgacaaagggcaatattttgcatcattcatggagtt -agaaaacgagccagtaatcttaccatgtcctcaaataaatacgctatcatccggatataa -tatattagatattttatgggaaaaacgaggagcggataatgatagaattatacagataga -taatggtagcaatatgctaattctgaacccgacacaatcagactctggtatttatatata -cattaccacgaacgaaacctactgtgacatgatgtcgttaaatttgacaatcgtgtctgt -ctcagaatcaaatatagatcttatctcgtatccacaaatagtaaatgagagatctactgg -taaaatggtatgtcccaatattaatgcatttatttctagtaacgtaaacacagaattata -tggagcggacatcgacgccttagaaataagagacttaaacaacggacacctggaattatt -accatagaagatgttagaaaaaatgatgctggttattatacatgtgttttagaatatata -tatatatatatatatatatatatatatatatatatatgggcaaaacatataacgtaacca -gaattataaaattagaggtacgggatagaataatacctcctactatgaaattaccagaag -gagtagtaacttcaataggtagtaatttgactattgcatgtagagtatcgttgagacttc -ccacaacggacaccgacgtcttttggataagtaatggtatatgtattacgaagaagaaga -cgaggacggagacggtagaataagtgtagcaaataaaatctatatgaccgataagagacg -tgttattacatcctggttaaacattaatcctgtcaaggaagaagatgctacaacgtttac -gtgtatggcgtttactattcctagcatcagcaaaacagttactgttagtaaacgtgaatg -tatgttgttacatttccatatcaattgagtttataagaattttttatacattatcttcca -acaaacaattgacgaacgtattgctatgattaactcccacaatactatatatattattaa -tcattaacttgcagactatacctagtagtgctattttgacatactcatgttcttgtgtaa -tcgcagtatctatattattaaagtacgtaaatctagctatagttttattatttaatttta -gataatatactgtctccgtatttttaaaaaattaccacatcctttattaaatcatgaatg -ggaatttctgtgtcatcgttagtatattgtgaacaacaagagcagatatctataggaaag -ggtggaatgcgatacattgatctatgtagttttaaaacatacgcgaactttgaagaattt -atataaatcatctcacgagatattgctctctgtcatattcatacacctgtataaactttc -tagacatcttacaatgtgttattttatgatcatatttacatatttactggtatatcaaag -atgttagattagttaatgggaatcgtctataataatgaatattaaacaattataggagga -gtttatacctacaaaaacatcataaaaatgagtcatcgtccgatttatgttttaaatata -ctaacattactaccttcagaaattatatacgaaatattatacatgctgacaattaacgat -ctttataatatatagtatccacctaccaaagtataattgtatttttctcatgtgatgtgt -gtaaaaaactgatattatataattatcttagtacctatgatgaagatgaagatgaagatg -aagatgatggtccgtatatattttgtatcattatcgttattgctattccatagttacgcc -atagacatcgaaaatgaaatcaccgaattcttcaataaaatgagagatactctaccagct -aaagactctaaatggttgaatccagtatgtatgtttggaggcacaatgaatgatatggcc -gctctaggagagccattcagtgcaaagtgtcctcctattgaagacagtcttttatcgcat -agatataaagactatgtggttaaatgggaaaggctagaaaagaatagacggcgacaggtt -tctaataaacgtgttaaacatggtgatttatggatagccaactatacatctaaattcagt -aaccgtaggtatttatgtaccgtaaccacaaagaatggtgactgtgttcagggtgtagtt -agatctcatgtgtggaaaccttcttcatgcattccaaaaacatatgaactaggtacttat -gataagtatggcatagacttatactgtggaattctttatgcgaaccattataataatata -acttggtataaagataataaggaaattaatatcgacgattttaagtattcacaagcggga -aaggaattaattattcataatccagagttagaagatagtggaagatacgactgttacgtt -cattacgacgacgttagaatcaagaatgatatcgtagtatcaagatgtaaaatacttacg -gttataccgtcacaagaccacaggtttaaactaatactagatccgaaaatcaacgtaacg -ataggagaacctgccaatataacatgcagtgctgtgtcaacgtcattatttgtcgacgat -gtactgattgaatgggaaaatccatccggatggattataggattagattttggtgtatac -tctattttaactagtagaggcggtatcaccgaggcgactttgtattttgaaaatgttact -gaagaatatataggcaatacatatacatgtcgtggacacaactattattttgataaaact -cttacaactacagtagtattggagtaaatacacaatgcatttttatatacattactgaat -tattattattaattatatcgtatttgtgctatagaatggatgaagatacgcgactatcta -ggtatttgtatctcaccgatagagaacatataaatgtagactctattaaacagttgtgta -aaatatcagatcctaatgcatgttatagatgtggatgtacggctttacatgagtactttt -ataattatagatcagtcaacggaaaatacaagtatagatacaacggttactatcaatatt -attcatctagcgattatgaaaattataatgaatattattatgatgattatgatagaactg -gtatgaacagtgagagtgataatatatcaatcaaaacagaatacgagaatgaatatgaat -tctatgatgaaacacaagatcaaagtacacaactagtagattacgacattaaactcaaaa -ccaatgaggatgattttgttgatgaattctatggttatgatagatcagtgggtgtccatg -attatatagatgtatcaattaataaagtagtatatggaagagagtctcacgtaagatggt -gggatatatggcaagaacataatgatggcgtatacagtataggaaaggagtgcatagata -atatatacgaagacagacataccgtagacgaattctacaagatagacagcgtatcagatg -tagatgacgcagaacatatatctcagataactaatgatgtatctacacaaacatgggaaa -agaaatcagagttagatagatacatggaaatgtatcctcgtcatagatatggtaagcatt -ctgtctttaagggattttctgacaaagttagaaaaaatgatttagacatgaacgtggtaa -aagaattactttctaacggtgcatctctaacaatcaaggatagcagtaataaggatccaa -ttgctgtttattttagaagaacaataatgaatttagaaatgattgatatcattaacaaac -atacaactatctatgaacgcaggtatatagtacactcctatctaaaaaattatagaaatt -tcgattatccatttttcagaaagttagttttgactaataaacattgtctcaacaattatt -gtaatataagcgacggcaaatatggaacaccactacatatattagcatctaataaaaaaa -taataactcctaattacatgaagttattagtgtataacggaaatgatataaacgcacgag -gtgaagatacacaaatgcgaactccattacacaaatatttgtgtaaatttgtatatcata -atattgaatatggtatccgatactataatgaaaagattatagacgcatttatagagttag -gagccgatctaactattccaaatgacgatggaatgataccagtagtttactgtatacact -caaatgccgaatatggttataacaatattactaacataaagataatacgtaaactactta -atcttagtagacatgcgtcacataatctatttagagatcgagtcatgcacgattatataa -gtaatacatatattgatcttgagtgtttagatatcattagatcacttgatgggtacgata -ttaattgttactttgaaggacgtacaccacttcattgcgctatacaatataacttcactc -agattgctgagtacttattagatcgaggagctgatatatcattaaagacagacgatggta -aaactgtatttgatttatcgttatgtagttacattcctcttaaatggactagctttttga -ttagtcgtctaccgcctaaaagtgtcatatgctcactgactaaccatataatagattatg -ttcttacgaacaatagacgtattatttggcagagtcaaatgattaataagtacgtactgt -tactggacccatccttttattatagattcagaaatgttatcgaaaacaaattagaccaat -acaataatcgttataatatgttcgaacacgatagggacgttaatgaaaagtatggcaaag -tcttacatgacctcgatacatatatcaaggatgtacaagtattaaaatctacttccatca -ctaataatataacactatacgacactattataaataataagtcagagtttcctatacgtc -gtgtaaacgacaaacaattaattaatctcataaaatccaatacatatcataatcttatcg -aaaaagttattaaaaatacattagagaaatatactttaactaatatagtcctcgagtata -tgatctcatctcgatctcaatcatcttatttgagtcgtattcctaatgagatattactcg -aaatattatataaactcgacatgtacgatttacgtaatctatatacaagatatatgagag -agaatgatatcacagagtatcatatagagaatacgaggtctgtttctacacagacatgaa -taatgaatacacatacaacgttttttttaatcttagatataacactaattacatcaagat -tatatattgaaatcgtaatttgagttgtctgatcatcatggatatcgaaaataatatacg -taacattagcaatcttttagatgattgatatattattatgcgatgtaatcataactatcg -gagatgtagaaattaaagcgcataaaactattttggttgccggatctacgtattttaaaa -caatgttcacaacatctatgatagcgagagatctagcaactagagtaaatatacagatgt -tcgataaagatgccgtcaaaaatattgtacagtacttatacaataggtatataagttcta -tgaatgtgatagacatattaaaatgcaccgactaagaacgtaaaacgaactatagaatgt -tatacaatgggtgatgataagtagaagatgttacccgatatacccatagcattatctagt -tatggcatgtgtgtattagatcaatacatatacattataagcggtcgtacccaacactga -ttatacatcggtacatacagtaaatagcatagatatggaggaggatacaaatatttcaaa -taaagttatgagatacgcgctgtcaataatatatggaagacattacctaacttctgaact -ggaactataaatccaggctctcgcataaagatgaatatatatgttgtatgcgacatcaaa -gatgaaaaaatgttaagacttatatatttagatataacacgaatatgtatgacggatggg -aattggtaacgatgacagaaagcagattgtcagctctgcatactattcttcatgacaata -ccataatgatgttacattgttatgaagcgtatatgttacaagatacatttaatgtgctta -cggaacatatatttagaaacatctactaacgattttttatgcttgtattattaatggtat -gtaatatgatttaattgattgtgtacacgataccaatttgtcgagtatgaatacggagta -caaacataaactgaagtttaacattatttatttatgatatacattatatacattatatac -attatatacattatatacattatatacattatatacattatatacattatatacattata -tacattatatacattatatacattatatacattatatacattatatacattatatacatt -atatacattatatacattatatatcgttattgtttggtctatgccatggatatctttaaa -gaactaatcttaaaacatacggatgaaaatgttttgatttctccagtttccattttatct -actttatctattctgaatcatggagcagctggttctacagctgaacaactatcaaaatat -atagagaatatgaatgagaatacacccgatgataagaaggatgacaataatgacatggac -gtagatattccgtattgcgcgacactagctaccgcaaataaaatatacggtagtgatagt -atcgagttccatgcctcattcctacaaaaaataaaagacgattttcaaactgtaaacttt -aataatgcgaaccaaacaaaggaactaatcaacgaatgggttaagacaatgacaaatggt -aaaattaattccttattgactagtccgctatccattaatactcgtatgatagttattagc -gccgtccattttaaagcaatgtggaaatatccattttctaaacatcttacatatacagac -aagttttatatttctaagaatatagttaccagtgttgatatgatggtgggtaccgagaat -gacttgcaatatgtacatattaatgaattattcggaggattctctattatcgatattcca -tacgagggaaactctagtatggtgattatactgccggacgacatagaaggtatatataac -atagaaaaaaatataacagatgaaaaatttaaaaaatggtgtggtatgttatctactaaa -agtatagacttgtatatgccaaagtttaaagtggaaatgacggaaccgtataatctggta -ccgattctagaaaatttaggacttactaatatatttggatattatgcagattttagtaag -atgtgtaatgaaactatcactgtagaaaaatttctacatacgacgtttatagatgttaat -gaggagtatacagaagtatcggccgttacaggagtattcatgactaacttttcgatggta -tatcgtatgaaggtctacataaaccatccattcatatacatgattaaagataacaccgga -catacactttttatagggaaatactgctatccgcaataaatataaacaatagacttttat -cacgttatctcatgtataaaatattacaaatagtatagcataaactaaagtcgatacata -cattaaaacttaaataataatgtaatttacaattaatagtataaactaaaaaaattaaaa -aattaaaaacaatatcattattataagtaatatcaaaatgacgatatacggattaatagc -gtatcttatattcgtgacttcatccatcgctagtccactttacattcccgttattccgcc -catttcggaagataaatcgttcaatagtgtagaggtattagtttctttgtttcccgatga -ccaaaaagactatacagtaacttctcagttcaataactacactatcggtaccaaagactg -gactatcaacgtactatccacacctgatggtctggacataccattgactaatataactta -ttggtcacggtttactataggtcgtgcattgttcaaatcagagtctgaggatattttcca -aaagaaaatgagtattctaggtgtttctatagaatgtaagaagccgtcgacattacttac -ttttttaaccgtgcgtaaaatgactcgagtatttaatagatttccagatatggcttatta -tcgaggagactgtctagaagccgtttatgtaacaatgacttataaaaatactaaaactgg -agagactgattacacgtacctctctaatggggggttgcctgcatactatcgtaatggggt -cgatggttgattattgattagtatattccttatattccttattctttttattcacacaaa -aagaacatttttataaacatgaaaccactgtctaaatgtaattatgatcttgatttatag -atgatgatcagccttcagaggattttgaccagtatgtttaatatgaaaaaaaacataact -attaagcgctattgcgctattgtgcttaattattttgctctataaactgaatatatagcc -acaattattgacgggcttgtttgtgaccgacaatcatgaattttcagaaattatctctgg -ctatatatcttacggtgacatgttcgtggtgttatgaaacatgtatgagaaaaactgcgt -tgtatcatgacattcaattggagcatgtagaagacaataaagatagtgtagcatcgctac -cgtacaagtatctacaagtagtcaaacaaagagaacgtagtagattgttggctacattta -attggacggatatagctgagggtgttagaaatgagttcattaaaatatgtgatatcaacg -gaacatatctatataattatactattgctgttagtataattattgattccacggaagaac -taccaacagttactccaattacaacatatgaaccttctatatataattatactatcgatt -atagcactgttattactactgaagaactacaagtgactccaacatatgcacctgtaacaa -ctcctcttccaacatcagcagttccttatgatcaacgatcgaataacaatgtaagtacta -tatctattcaggtactgagtaaaatattgggagtcaatgaaacagaattaactaattatc -ttattatgcataaaaatgacactgttgacaataacaccatggttgatgatgagacatcta -acaataacacattacatggtaatataggatttttggaaataaataattgttataatgttt -ctgtgtcagatgctagttttagaataacattagtaaacgatacttctgaagaaattttgc -taatgctaacaggaactagttcatccgacaccttcatatcttccaccaatatcactgaat -gtttgaaaacattaatcaataatgtgtcgattaatgatgtacttataacacaaaatatga -atgtaacatctaattgtgataaatgctcaatgaatttgatggcatccgttattcctgcag -ttaatgaatttaacaatacgttgatgaaaattggtgtaaaagatgatgaaaacaatacgg -tatataaatattataattgtaaactaactacaaattctacatgtgatgagttaatcaatt -tagatgaagtcattaacaacataactctgacaaatattatacacaatagtgtttcgacaa -ctaacagcagaaaaagacgagatctgaatgatgagtttgaattttccacttccaaggaat -tagattgtctttacgaatcatatggtgtaaacgatgatataagtcattgttttgcatcac -ctagacgtagacgatctgacgacaaaaaggagtacatggacatgaaattattcgaccacg -cgaaaaaagatttaggaatagacagtgttattcctagaggtacaacccatttccaagtag -gtgcatctggtgcaagtggtggtgttgtaggagatagtttcccatttcaaaatgttaaat -cgcgtgccagtctattggcggaaaaaataatgcctagagtacctattactgctaccgaag -ctgatctatatgcaactgtaaatagacaacccaagttaccagcaggtgttaaaagtactc -cgtttacagaggcgcttgtgtctacgataaaccaaaagctttctaatgttagagaggtaa -cttatgcttcgctcaatctgccaggatcaagtggctatgttcatagaccatctgattctg -ttatttatagcagtataagacggtcacgtttacctagtgatagcgatagtgattatgagg -atatacaaactgttgttaaggaatataatgaaagatatggtagatcagtcagtagaacac -agtcatcaagtagtgaaagcgattttgaagatatagatactgttgttagggaatatagac -aaaaatatggcaatgcaatggcaaaaggacgtagtagttcccctaaacctgatccattat -atagtactgttaagaaaacaactaaaagtctatctactggtgtagacatagttacaaaac -aatcagactattctctattacctgacgttaatactggcagttctattgtgtcacctctca -ccagaaaaggagctactagacgacgacctagacgccctacaaatgatggtctacagagtc -caaatcctcctctccgtaatccacttcctcaacatgatgattattctcctccacaagtac -acagacctccaccacttcctcctaaaccagtccaaaattcgccacaacttccccctagac -cagtaggtcaattactacctcctcctatagatcaaccagataaaggatttagtaagtttg -tatcacctagacggtgtagaagagcaagctctggagtcatatgtggtatgatacaatcaa -aaccaaacgatgatacctattcacttcttcaacgatcaaaaattgaaccagaatatgtgg -aggttggtaatggtatacccaagaacaatgttcctgtaataggtaataaacatagtaaaa -aatatacatcgacgatgtcaaaaatatcaacaaaatttgataaatctacggcatttggag -cagcaatgttactaactggtcagcaggccattagccaacagactagatcaactacgttga -gtagaaaagatcagatgagtaaggaagaaaagatattcgaagcagttacaatgagtctat -caactataggttcaacgttgacgtctgcaggtatgacgggtggtccaaaactaatgattg -caggaatggctataacggctataactggtataatagatacgataaaagatatatattaca -tgttttcaggacaggagaggccagtagatcctgttattaaattatttaataagtacactg -gcttaatgtccgataataataaaatgggtgtaagaaaatgtttgacacccggtgacgaca -cacttatttatatcgcatacagaaacgataccagttttaaacagaatacggatgcgatgg -ctttgtatttcttagatgttatcgattcagagatcctatatctaaacacatcaaatttag -ttctagagtatcaactaaaggtggcttgccccataggaacattaagatctgtagatgtgg -acataactgcgtatacaatattatatgatacagcggataatattaagaaatacaagttta -tcagaatggcaacgctactatccaaacatccagttattagattgacatgtggtttagcag -caacattggtgattaaaccgtacgaggtacccatcagtgatatgcaactactaaaaatgg -cgacgcctggtgaaccagaatccactaaatctataccatccgatgtctgtgataggtatc -ctctaaagaaattctatcttttagctggtggttgtccctatgatacatctcaaactttta -ttgtacatactacttgcagtattctactaagaacagctacacgggatcagtttagaaaca -gatgggtgttacaaaatccatttagacaagaagggacatataagcaactgtttaccttta -gcaaatacgattttaacgacaccataatcgatcctaatggtgtggtgggtcatgctagct -tttgtaccaatagaagcagcaaccaatgtttctggtccgaacctatgatattggaagatg -tatcatcgtgtagttctagaactagaaaaatatacgtaaaactgggaatatttaatgctg -aaggttttaatagttttgtactaaattgtccaactgggtctacacctacatacatcaaac -ataaaaatgcggacagtaacaatgttatcatagagctacctgtaggtgattacggcacag -ccaaattgtattcagcaacaaaaccatcgaggatagctgtgttctgcacacataactatg -ataaacgattcaaatcagatattatagttctaatgtttaataaaaacagcggtattccat -tttggagcatgtacacaggaagtgtaactagtaaaaatagaatgtttgccacattggcta -gaggaatgccgtttagatcaacgtattgcgataacagacgacgatcaggttgttattatg -caggaataccatttcatgaagatagtgtagaaacagatatacattatggaccagaaataa -tgttaaaggaaacatatgacataaacagtattgacccacgagttataacaaagtcaaaga -cccattttcctgctccattgagtgtaaaattcatggttgacaatttaggaaatggatatg -acaaccctaattcattttgggaagatgctaaaactaagaaacggacatatagtgcaatga -cgataaaagtcctaccatgtacagtgagaaataaaaatatagactttggatataactatg -gagatattatttctaatatggtttatctacaatctactagtcaggattatggagatggta -ccaaatatacatttaaatccgtaactagatcagatcatgagtgtgaatctagcttagatc -taacgtctaaggaagtaactgtgacatgtcctgcgtttagtataccaagaaatatatcaa -catatgaaggtctatgctttagtgttactacatctaaagatcattgtgctacaggtattg -gttggttaaaatctagtggttatgggaaggaagatgctgataaaccacgtgcttgttttc -atcattggaattattacacactgtcgttggattattactgttcatacgaagatatttgga -gaagcacctggcctgactatgatccatgtaagtcatatatccatatagagtatagagata -catggatagaatctaatgtgttacagcaacctccttacacattcgaattcattcatgaca -attctaacgaatatgtggataaagaaattagtaacaaattaaatgatctgtacaatgaat -acaagaagattatggaatatagcgacggatcattgccggcgtctataaacagattagcaa -aggcattgacttcagagggtagagaaatagcaagtgttaatatagatggtaatctgttag -atatcgcatatcaagcagataaggaaaagatggccgacatacagacaagaataaatgata -ttattagagatttgtttatacacactctatcagacaaagatataaaagacattatagaat -ccgaagaaggtaagagatgttgtataatagatgttaagaacaatcttgttaaaaagtact -attctattgataattatctatgtgatactttagatgattatatatacacctctgtagaat -ataacaaatcctatgtgttagtaaacgatacttatataagctatgactatcttgaatcat -caggtgtagttgttctatcatgttatgaaatgactataatctccttggatacaaaagacg -ccaaagatgctatagaagatgtgatagtagcaagtgcggtagccgaagcattgaatgaca -tgtttaaggaatttgataaaaacgtaagtgctattataataaaagaagaagataattatc -taaacagttcgcccgatatctaccatataatatatatcataggtggcactattctgctac -tgttagtcattattttaatattggcaatttatatagcgcgcaataaatacagaaccagga -aatatgaaataatgaaatatgacaatatgagcattaaatctgagcatcatgatagtcttg -aaacagtgtctatggaaattattgataatcggtactaataaaatagtttaactcttttag -aaccagtttggtactgtaatttcagttcattactcgttgagaatattgatgatttttttt -aaatgagtatcggtagttacatattaccatatcatccattatataatcgatgatgcatgt -attagaatactttccgaataagtcttctaaatattgtattaattatgaaaaactatgcta -tgtgagtatgattcaaagatgtttaatgatacgatactagattttatctctagcgagatt -gtttagaatcatttatcataactatgtttaataaattcatcaacgaatatcgataaagac -ctcttgtaattcgagtataggaagtagtattaccatatcaacttccgagttaacaattac -tctaaaacatgaggattgtactcctgtctttattggagatcactatttagtcgttgataa -actagtaacctcaggtttctttacaaacgataaagtacaacatcaagacctcacaacaca -gtgcaagattaatctagaaatcaaatgtaattctggaggagaatctagacaactaacacc -cacggcgaagtatactttatgcctcattcagaaacggtaactgtagtaggagactgtctc -tctaatctcgatgtatatataatatataccaatacggacgcgatatattccgacatgaat -ggcgtcgcttatcatatgttatatcctaaatgttgatcatattccacaaatgattgtgaa -cgagattaaatcatctaacaaataattagttttttatgacattaacatataataaataaa -ttaatcattattgacttaacgatgacgaaagttatcattatcttaggattcttgattatt -aatacaaattcgttgtgtctatgaaatgtgaacaaggtgtctcatattataatgcacaag -aattaaagtgttgtaaactatctagccaggaacatattcagattatcgatgtgataaata -cagcgataccatctgtggacattgtccaagtgacacattcacgtcaatatataatcgttc -tcctcggtgtcatagttgtagaggtcacaccttgtacacctaccacaaatagaatatgtc -attgtgactcgaatagttatcgtctccttaaagcttctgatggtaactgtgttacatgtg -ctcctaaaacaaaatatggtcgtgtgtacggaaagaaaggagaaaatgatatggaatacc -atttgtaagaaatgtcggaagggtacttattcagatattgtatctgactctgatcaatgt -aaacctatgacaagataagacttactcgcatctactggatagacataaatatcctcctcg -taataatgaaatataatatacactaattattaatatcaatcgagtattaacatataagtt -atttttaaaccccttttgggttccgtcctaaacggcgtttcggtctgtgtcgccaccatg -gtcacaccgagcctctgcgtgctcctccatcgaggacgacttcaactatgacagctcggt -ggcgtctgccagcgtgtacatacgaatggcatttctaagaaaagtctacggtatcctttc -tacaatttcctttaacaacggcaacagctgcagtatttttatactttgaatgcatcggac -atttatacaagggagtcctgttctaatattggcatcaatgttcggatctataggcttgat -tttcgcattgactttacacagacatgaacatcccctgaatctgtacatactttgtggatt -tacactgttagaatctctaacgctggcctctgttgttactttctatgatgcacgtatcgt -tatgcaagctttcatgttgactactgcagtgtttcttgctctgactacatatactctaca -atcaaagagagatttcagtaaacttgtaacaggattgtttgctgctttctggattttaat -tttgtcaggagtcttgaggataaagtttaaaatagaattaataaagaacatataggtcat -tttttaaacatggatagaaaccaaggttgttagttaataatatacaagatattttttctc -actctgatccatgtaaaccaaggacgagagacactctcattcctcattcacgacaccatt -aaaaatggaaattaaagccctctattaagcacagacggctacaggtctaccatcaggtta -ccttcgtctaccttcacaatggcctctccttgtgcccagttcagtccctgtcattgccac -gctactaaggactccctgaataccgtgactgacgtcagacattgtctgactgaatacatc -ctgtgggtttctcatagatggacccatagagaaagcgcagggcctctctacaggcttctc -atctctttcagaattgatgcaatggagctatttggtagcgagttgaaggagttctcgaat -tcacttccgtgggacaatatcgacaattgcgtggagatcattaaatgtttcatcagaaat -gactccatgaaaaccgccaaagaactttgtgcaataattggactttgtactcaatcagct -attgtcactggaagagtcttcaatgataagtatatcgacatactacttatgctgcgaaag -attctgaacgagaacgactatctcaccctcttggatcatatcctcactgctaaatactaa -atctccttcatgctctctcactaatactcttactcactacactttttatcatcttatgat -gaatgattgccttcatcattttttcgtggaatataatataggaataattagcaccagaat -agctatggatatctcgttaagaatattctctataagagacataatgtagacatagttatt -atatccttcttagataagtgttacgctactggaaagtttccatcgttattattacatgaa -gatgatataattaaaccaacattgagattggctcttatgttagctggattgaattactgt -aataaatgcatcgagtatagagggatatagcaattctcgataatagtcatgcaatatttg -aatgagactgataatttaggtaatacagtactacacacatatctttctagattatatatc -gttaaaaatctgtaagatgtatatttctcataagtatccactgtgtaatattattaatgg -atatatagataacgcaatagggactaatagtattgtaaaagatataatcgactatttacg -tacatatccagatatctatattcctactagtttgctgcgtagttgcatcattgatatgca -tgatttatcaggattcagagatgaattactaagtaaactacaatcccacaataagtaaga -atcaaatatcaaaaactcacttttgatttttctagtcttaagtaatacatatatttatta -atagacctatgaaataaaaaaaggtaacaatggattcgcgtatagctatttacgtattag -tatcggcatctcttttgtatcttgttaattgtcacaaactagtacattacttcaatctga -aaataaatggaagtgatataactaatacagcagatatattgctggacaattatccaatta -tgacctttgatggaaaggatatttatccatctatctcgttcatggtcggtaataaacttt -tcctagatctttataaaaatatctttgaagaatttttcagactatttcgagtatctgtaa -gtagtcaatacgaggaattagaatattattattcatgtgattatactaacaaccgtccta -caattaaacaacattacttttataacggcgacgaatatactgaaattgatagatcgaaaa -aagccactaataaaaacagttggttaattacttcaggctttagactacaaaaatggttcg -atagcgaagattgtataatttatctcagatctttagttagaagaatggaagacagtaaca -aaaacagtaaaaaaacttagtacttagatatcgaaaaaatatatttttgtagactcttga -gaatagaaggaaaacatgtacataattataaaaaatgaaaatcaatggcgaataagacag -tgcgattcgcaccatggagtcggtagatttcatggctgtcgatgagcagtttcacgacga -cctcgatctttggtcattatctttggtagatgattataaaaaacatggattaggtgttga -ctgttatgttctagaaccagttgttgacaggaaaatatttgatagatttctccttgaacc -aatttgtgatcctgtagatgttctgtatgattattttaggattcatagagataatattga -tcagtatatagtagatagactgtttgcatatattacatataaagatattatatctgcatt -agtgtcaaagaattatatggaagatattttctctataattattaagaattgtaattctgt -gcaagatctcttactttactatctatctaatgcatatgtagaaatagacattgttgatct -tatggtagatcatggggctgtaatatataaaatagaatgcttgaatgcctattttagggg -aatatgtaaaaaggaaagtagtgttgttgagtttattttgaattgtggtatcccagatga -aaatgatgttaaattagatctatataaaataattcagtatactaggggattccttgtaga -tgaacccacagtattagaaatttataagctttgtatcccatatattgaagatatcaatca -actagatgctggtggaaggaccttgctttatcgcgctatctatgcaggttatatagattt -agtatcatggctattagaaaatggagcaaatgtcaacgcagtaatgagtaatggatatac -atgtcttgacgtggccgtggataggggatctgtcatcgcccgtagggaagcacatcttaa -aatattagaaatattgcttagagaaccattgtctattgactgtataaaattagctatact -taataatacaattgaaaaccatgatgtgataaagctctgtatcaagtattttatgatggt -agattattcactttgtaatgtgtatgcatcatcactctttgattatataattgattgtaa -acaagaattggagtacattaggcagatgaaaattcataatacaaccatgtatgagttaat -ctataatagagacaaaaacaagcatgcttcccatattctacataggtattctaaacatcc -agttttgacacagtgtatcactaaaggattcaagatttacacagaagtaaccgagcaggt -cactaaagctctaaacagacgtgctctaatagatgagataataaacaatgtatcaactga -tgacaatctcctatcaaaacttccattagaaattagggatctaattgtttcacaagctgt -catatagagttctatccacccacctttcttgaaatgagttaatagtcataagttagttaa -gtcataagttagttaagtcataagttagttaagtcataagttagttaagtcataagttag -ttaagtcataagttagttaagtcataagttagttaagtcataagttagtttatagtctaa -cacttctaatttttataccttgatctttttctctaattatgaaaaagtaaatcattatga -agatggatgaaatggacgagattgtgcgcatcgttaacgatagtatgtggtacgtaccta -acgcatttatggacgacggtgataatgaaggtcacatttctgtcaataatgtctgtcata -tgtatctcgcattctttgatgtggatatatcatctcatctgtttaaattagttattaaac -actgcgatctgaataaacgactaaaatgtggtaactctccattacattgctatacgatga -atacacgatttaatccatctgtattaaagatattgttacgccacggcatgcgtaactttg -atagcaaggataaaaaaggacatattcctctacaccactatctgattcattcactatcaa -tcgataacaagatctttgatatactaacggaccccattgatgactttagtaaatcatccg -atctattgctgtgttatcttagatataaattcaatgggagcttaaactattacgttctgt -acaaattattgactaaaggatctgaccctaattgcgtcgatgaggatggactcacttctc -ttcattactactgtaaacacatatccgcgttccacgaaagcaattattacaagtcaaaga -gtcacactaagatgcgagctgagaagcgattcatctacgcgataatagatcatggagcaa -acattaacgcggttacgaaaatcggaaatacgccgttacacacttaccttcaacagtata -ccaaacatagtcctcgtgtggtgtatgctcttttatctcgaggagccgatacgaggatac -gtaataatcttaattgtacacccatcatggaatacataaagaacgattgtgcaacaggtc -atattctcataatgttactcaattggcacgaacaaaaatacgggaaattacaaaaggaag -aaggacaacatctactttatctattcataaaacataatcaaggatatggaagtcgctctc -tcaatatactacggtatctactagatagattcgacattcagaaagacgaatactataata -caatgactcctcttcataccgccttccagaattgcaataacaatgttgcctcatacctcg -tatacattggatacgacatcaaccttccgactaaagacgataagacagtattcgacttgg -tgtttgaaaacagaaacattatatacaaggcggatgtcgttaatgacattatccaccaca -gactgaaagtatctctacctatgattaaatcgttgttctacaagatgtcggagttctctc -cctacgacgatcactacgtaaagaagataatagcctactgcctattaagggacgagtcat -ttgcggaactacatactaaattctgtttaaacgaggactataaaagtgtatttatgaaaa -atatatcattcgataagatagattccatcatcgaaaaatgtagtcgtgacataagtctcc -tcaaagagattcgaatctcagacaccgacttgtatacggtattgagaacagaagacattc -ggtatcacacatatctcgaagccatacattcagacaaacgcatttcatttcccatgtacg -acgatctcatagaacagtgtcatctatcgatggagcataaaagtaaactcgtcgacaaag -cactcaataaattagagtctaccatcgatagtcaatctagactatcgtatttgcctccgg -aaattatgcgcaatatcataaccaagctaagcgactaccatctaaacagtatgttgtacg -gaaagaaccattacaaatattatccatgatagaaagaaaatatttaaaaaataatctata -tgattggagaagtaggaaacaaacagtaacaagacgacgattactacattattaaatcat -gaggtccgtattatactcgtatatattgtttctctcatgtataataataaacggaagaga -tatagcaccacatgcaccatccaatggaaagtgtaaagacaacgaatacagaagccgtaa -tctatgttgtctatcgtgtcctccgggaacttacgctttcagattatgtgatagcaagac -taatacacaatgtacaccgtgtggttcggatacctttacatctcacaataatcatttaca -ggcttgtctaagttgtaacggaagatgtgatagtaatcaggtagagacgcgatcgtgtaa -cacgactcacaatagaatctgtgaatgctctccaggatattattgtcttctcaaaggagc -atcagggtgtagaacatgtatttctaaaacaaagtgtggaataggatacggagtatccgg -atacacgtctaccggagacgtcatctgttctccgtgtggtcccggaacatattctcacac -cgtctcttccacagataaatgcgaacccgtcgtaaccagcaatacatttaactatatcga -tgtggaaattaacctgtatccagtcaacgacacatcgtgtactcggacgaccactaccgg -tctcagcgaatccatctcaacgtcggaactaactattaccatgaatcataaagattgtga -tccagtctttcgtgcagaatacttctctgtccttaataatgtagcaacttcaggattctt -tacaggagaaaatagatatcagaatacttcaaagatatgtactctgaatttcgagattaa -atgtaacaacaaagattcatcttccaaacagttaacgaaaacaaagaatgatactatcat -gccgcattcagagacggtaactctagtgggcgactgtctatctagcgtcgacatctacat -actatatagtaataccaatactcaagactacgaaaatgatacaatctcttatcatatggg -taatgttctcgatgtcaatagccatatgcccgctagttgcgatatacataaactgatcac -taattcccagaatcccacccacttatagtaagtttttttacctataaataataaatacaa -taattaatttctcgtaaaagtagaaaatatattctaatttattatatggtaagaaagtag -aatcatctagaacagtaatcaatcaatagcaatcatgaaacaatatattgtcctggcatg -catgtgcctagtggcagctgctatgcctactagtcttcaacaatcttcatcctcgtgtac -tgaagaagaaaacaaacatcatatgggaatcgatgttattatcaaagtcacaaagcaaga -ccaaacaccgaccaatgataagatttgtcaatccgtaacggaagttacagagaccgaaga -tgatgaggtatccgaagaagttgtaaaaggagatcccaccacttattacactatcgtcgg -tgcgggtcttaacatgaactttggattcaccaaatgcccaaagattttatccatctccga -atcctctgatggaaacactgtgaatactagattgtccagcgtgtcaccgggacaaggtaa -ggactctcccgcgatcacgcgtgaagaagctctggctatgatcaaagactgtgagatgtc -tatcgacatcagatgtagcgaagaagagaaagacagtgacatcaagacccatccagtact -tgggtctaacatctcacataagaaagtgagttacaaagatatcatcggttcaacgatcgt -tgatacaaaatgtgtcaagaacctagagtttagcgtacgtatcggagacatgtgtgagga -atcatctgaacttgaagtcaaggatggattcaagtatgtcgacggatcggcatctgaagg -tgcaaccgatgatacttcactcatcgattcaacaaaactcaaagcatgtgtctgaatcga -taactctattcatctgaaaatggatgagttgggttaatcgaacgattcagacaccgcacc -acgaattaaaaaagaccgggcactatattccggtttgcaaaacaaaaatatttaactaca -ttcacaaaaagttacctctcgttacttcttctttctgtttcaatatgtgatacgatatga -tcactattcgtattctcttggtctcataaaaaagttttacaaaaaaaaaaaaaaaaatat -ttttattctctttctctcttcgatggtctcacaaaaatattaaacctctttctgatgtct -caactatttcgtaaacgataacgtccaacaatatattctcgtagagcttatcaacatcct -tataccaatctaggttgtcagacaattgcatcataaaataatgtttataatttacacgtt -aacatcatataataaacgtatatagttaatatttttggaatataaatgatctgtaaaatc -catgtaggggacactgctcacgttttttctctagtacataatttcacacaagtttttata -cagacaaattaattctcgtccatatattttaaaacattgacttttgtactaagaaaaata -tcttgactaaccatctctttctctcttcgatgggtctcacaaaaatattaaacctctttc -tgatggagtcgtaaaaagtttttatcctttctctcttcgataggtctcacaaaaatatta -aacctctttctgatggtctctataaacgattgatttttcttaccctctagagtttcctac -ggtcgtgggtcacacatttttttctagacactaaataaaatagtaaaat diff --git a/data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/tree.json b/data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/tree.json deleted file mode 100644 index dada2af1..00000000 --- a/data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/tree.json +++ /dev/null @@ -1,91637 +0,0 @@ -{ - "version": "v2", - "meta": { - "title": "Nextclade reference tree for hMPXV-1 clade B.1 (reference seq: ON622721.3 in NC_063383.1 coordinates)", - "updated": "2023-07-31", - "build_url": "https://github.com/nextstrain/monkeypox", - "data_provenance": [ - { - "name": "GenBank", - "url": "https://www.ncbi.nlm.nih.gov/genbank/" - } - ], - "maintainers": [ - { - "name": "Nextstrain team", - "url": "http://nextstrain.org" - } - ], - "display_defaults": { - "color_by": "lineage", - "map_triplicate": false, - "distance_measure": "div", - "transmission_lines": false - }, - "genome_annotations": { - "nuc": { - "end": 197209, - "start": 1, - "strand": "+", - "seqid": "config/genemap.gff", - "type": "source" - }, - "NBT03_gp052": { - "end": 55141, - "seqid": "config/genemap.gff", - "start": 54752, - "strand": "+", - "type": "gene" - }, - "NBT03_gp174": { - "end": 190940, - "seqid": "config/genemap.gff", - "start": 190410, - "strand": "+", - "type": "gene" - }, - "NBT03_gp175": { - "end": 192367, - "seqid": "config/genemap.gff", - "start": 191054, - "strand": "+", - "type": "gene" - }, - "OPG001": { - "end": 196375, - "seqid": "config/genemap.gff", - "start": 195635, - "strand": "+", - "type": "gene" - }, - "OPG002": { - "end": 195508, - "seqid": "config/genemap.gff", - "start": 194459, - "strand": "+", - "type": "gene" - }, - "OPG003": { - "end": 194369, - "seqid": "config/genemap.gff", - "start": 192603, - "strand": "+", - "type": "gene" - }, - "OPG005": { - "end": 189660, - "seqid": "config/genemap.gff", - "start": 189199, - "strand": "+", - "type": "gene" - }, - "OPG015": { - "end": 6156, - "seqid": "config/genemap.gff", - "start": 4843, - "strand": "+", - "type": "gene" - }, - "OPG019": { - "end": 8008, - "seqid": "config/genemap.gff", - "start": 7580, - "strand": "+", - "type": "gene" - }, - "OPG021": { - "end": 10315, - "seqid": "config/genemap.gff", - "start": 9587, - "strand": "+", - "type": "gene" - }, - "OPG022": { - "end": 10858, - "seqid": "config/genemap.gff", - "start": 10478, - "strand": "+", - "type": "gene" - }, - "OPG023": { - "end": 12900, - "seqid": "config/genemap.gff", - "start": 10918, - "strand": "+", - "type": "gene" - }, - "OPG024": { - "end": 13228, - "seqid": "config/genemap.gff", - "start": 13034, - "strand": "+", - "type": "gene" - }, - "OPG025": { - "end": 15267, - "seqid": "config/genemap.gff", - "start": 13375, - "strand": "+", - "type": "gene" - }, - "OPG027": { - "end": 16377, - "seqid": "config/genemap.gff", - "start": 15925, - "strand": "+", - "type": "gene" - }, - "OPG029": { - "end": 17069, - "seqid": "config/genemap.gff", - "start": 16602, - "strand": "+", - "type": "gene" - }, - "OPG030": { - "end": 17833, - "seqid": "config/genemap.gff", - "start": 17213, - "strand": "+", - "type": "gene" - }, - "OPG031": { - "end": 18828, - "seqid": "config/genemap.gff", - "start": 17878, - "strand": "+", - "type": "gene" - }, - "OPG034": { - "end": 20005, - "seqid": "config/genemap.gff", - "start": 19361, - "strand": "+", - "type": "gene" - }, - "OPG035": { - "end": 20404, - "seqid": "config/genemap.gff", - "start": 20051, - "strand": "+", - "type": "gene" - }, - "OPG036": { - "end": 21064, - "seqid": "config/genemap.gff", - "start": 20531, - "strand": "+", - "type": "gene" - }, - "OPG037": { - "end": 22433, - "seqid": "config/genemap.gff", - "start": 21105, - "strand": "+", - "type": "gene" - }, - "OPG038": { - "end": 23159, - "seqid": "config/genemap.gff", - "start": 22497, - "strand": "+", - "type": "gene" - }, - "OPG039": { - "end": 24118, - "seqid": "config/genemap.gff", - "start": 23264, - "strand": "+", - "type": "gene" - }, - "OPG040": { - "end": 25478, - "seqid": "config/genemap.gff", - "start": 24351, - "strand": "+", - "type": "gene" - }, - "OPG042": { - "end": 27097, - "seqid": "config/genemap.gff", - "start": 25823, - "strand": "+", - "type": "gene" - }, - "OPG043": { - "end": 27955, - "seqid": "config/genemap.gff", - "start": 27125, - "strand": "+", - "type": "gene" - }, - "OPG044": { - "end": 28540, - "seqid": "config/genemap.gff", - "start": 28091, - "strand": "+", - "type": "gene" - }, - "OPG045": { - "end": 29262, - "seqid": "config/genemap.gff", - "start": 28603, - "strand": "+", - "type": "gene" - }, - "OPG046": { - "end": 29729, - "seqid": "config/genemap.gff", - "start": 29274, - "strand": "+", - "type": "gene" - }, - "OPG047": { - "end": 31194, - "seqid": "config/genemap.gff", - "start": 29746, - "strand": "+", - "type": "gene" - }, - "OPG048": { - "end": 32164, - "seqid": "config/genemap.gff", - "start": 31205, - "strand": "+", - "type": "gene" - }, - "OPG049": { - "end": 33151, - "seqid": "config/genemap.gff", - "start": 32195, - "strand": "+", - "type": "gene" - }, - "OPG050": { - "end": 33408, - "seqid": "config/genemap.gff", - "start": 33181, - "strand": "+", - "type": "gene" - }, - "OPG051": { - "end": 33649, - "seqid": "config/genemap.gff", - "start": 33425, - "strand": "+", - "type": "gene" - }, - "OPG052": { - "end": 33995, - "seqid": "config/genemap.gff", - "start": 33801, - "strand": "+", - "type": "gene" - }, - "OPG053": { - "end": 34690, - "seqid": "config/genemap.gff", - "start": 34052, - "strand": "+", - "type": "gene" - }, - "OPG054": { - "end": 35996, - "seqid": "config/genemap.gff", - "start": 34677, - "strand": "+", - "type": "gene" - }, - "OPG055": { - "end": 37083, - "seqid": "config/genemap.gff", - "start": 36019, - "strand": "+", - "type": "gene" - }, - "OPG056": { - "end": 39034, - "seqid": "config/genemap.gff", - "start": 37127, - "strand": "+", - "type": "gene" - }, - "OPG057": { - "end": 40195, - "seqid": "config/genemap.gff", - "start": 39077, - "strand": "+", - "type": "gene" - }, - "OPG058": { - "end": 40434, - "seqid": "config/genemap.gff", - "start": 40213, - "strand": "+", - "type": "gene" - }, - "OPG059": { - "end": 40633, - "seqid": "config/genemap.gff", - "start": 40484, - "strand": "+", - "type": "gene" - }, - "OPG060": { - "end": 41182, - "seqid": "config/genemap.gff", - "start": 40706, - "strand": "+", - "type": "gene" - }, - "OPG061": { - "end": 41884, - "seqid": "config/genemap.gff", - "start": 41189, - "strand": "+", - "type": "gene" - }, - "OPG062": { - "end": 42252, - "seqid": "config/genemap.gff", - "start": 41947, - "strand": "+", - "type": "gene" - }, - "OPG063": { - "end": 43688, - "seqid": "config/genemap.gff", - "start": 42249, - "strand": "+", - "type": "gene" - }, - "OPG064": { - "end": 45898, - "seqid": "config/genemap.gff", - "start": 43685, - "strand": "+", - "type": "gene" - }, - "OPG065": { - "end": 46483, - "seqid": "config/genemap.gff", - "start": 46022, - "strand": "+", - "type": "gene" - }, - "OPG066": { - "end": 47428, - "seqid": "config/genemap.gff", - "start": 46649, - "strand": "+", - "type": "gene" - }, - "OPG068": { - "end": 49904, - "seqid": "config/genemap.gff", - "start": 48201, - "strand": "+", - "type": "gene" - }, - "OPG069": { - "end": 50486, - "seqid": "config/genemap.gff", - "start": 49986, - "strand": "+", - "type": "gene" - }, - "OPG070": { - "end": 51411, - "seqid": "config/genemap.gff", - "start": 50590, - "strand": "+", - "type": "gene" - }, - "OPG071": { - "end": 54438, - "seqid": "config/genemap.gff", - "start": 51418, - "strand": "+", - "type": "gene" - }, - "OPG072": { - "end": 54757, - "seqid": "config/genemap.gff", - "start": 54470, - "strand": "+", - "type": "gene" - }, - "OPG074": { - "end": 57125, - "seqid": "config/genemap.gff", - "start": 55128, - "strand": "+", - "type": "gene" - }, - "OPG075": { - "end": 57498, - "seqid": "config/genemap.gff", - "start": 57172, - "strand": "+", - "type": "gene" - }, - "OPG076": { - "end": 57630, - "seqid": "config/genemap.gff", - "start": 57523, - "strand": "+", - "type": "gene" - }, - "OPG077": { - "end": 58583, - "seqid": "config/genemap.gff", - "start": 57645, - "strand": "+", - "type": "gene" - }, - "OPG078": { - "end": 58811, - "seqid": "config/genemap.gff", - "start": 58590, - "strand": "+", - "type": "gene" - }, - "OPG079": { - "end": 59621, - "seqid": "config/genemap.gff", - "start": 58812, - "strand": "+", - "type": "gene" - }, - "OPG080": { - "end": 62018, - "seqid": "config/genemap.gff", - "start": 59703, - "strand": "+", - "type": "gene" - }, - "OPG081": { - "end": 62285, - "seqid": "config/genemap.gff", - "start": 62046, - "strand": "+", - "type": "gene" - }, - "OPG082": { - "end": 63452, - "seqid": "config/genemap.gff", - "start": 62304, - "strand": "+", - "type": "gene" - }, - "OPG083": { - "end": 64716, - "seqid": "config/genemap.gff", - "start": 63445, - "strand": "+", - "type": "gene" - }, - "OPG084": { - "end": 66752, - "seqid": "config/genemap.gff", - "start": 64722, - "strand": "+", - "type": "gene" - }, - "OPG085": { - "end": 68531, - "seqid": "config/genemap.gff", - "start": 66756, - "strand": "+", - "type": "gene" - }, - "OPG086": { - "end": 68863, - "seqid": "config/genemap.gff", - "start": 68528, - "strand": "+", - "type": "gene" - }, - "OPG087": { - "end": 69519, - "seqid": "config/genemap.gff", - "start": 68857, - "strand": "+", - "type": "gene" - }, - "OPG088": { - "end": 69863, - "seqid": "config/genemap.gff", - "start": 69489, - "strand": "+", - "type": "gene" - }, - "OPG089": { - "end": 71170, - "seqid": "config/genemap.gff", - "start": 69866, - "strand": "+", - "type": "gene" - }, - "OPG090": { - "end": 71370, - "seqid": "config/genemap.gff", - "start": 71179, - "strand": "+", - "type": "gene" - }, - "OPG091": { - "end": 71867, - "seqid": "config/genemap.gff", - "start": 71370, - "strand": "+", - "type": "gene" - }, - "OPG092": { - "end": 72947, - "seqid": "config/genemap.gff", - "start": 71832, - "strand": "+", - "type": "gene" - }, - "OPG093": { - "end": 73760, - "seqid": "config/genemap.gff", - "start": 72978, - "strand": "+", - "type": "gene" - }, - "OPG094": { - "end": 74802, - "seqid": "config/genemap.gff", - "start": 73780, - "strand": "+", - "type": "gene" - }, - "OPG095": { - "end": 75555, - "seqid": "config/genemap.gff", - "start": 74803, - "strand": "+", - "type": "gene" - }, - "OPG096": { - "end": 75865, - "seqid": "config/genemap.gff", - "start": 75587, - "strand": "+", - "type": "gene" - }, - "OPG097": { - "end": 76875, - "seqid": "config/genemap.gff", - "start": 75841, - "strand": "+", - "type": "gene" - }, - "OPG098": { - "end": 77655, - "seqid": "config/genemap.gff", - "start": 76900, - "strand": "+", - "type": "gene" - }, - "OPG099": { - "end": 78051, - "seqid": "config/genemap.gff", - "start": 77665, - "strand": "+", - "type": "gene" - }, - "OPG100": { - "end": 78466, - "seqid": "config/genemap.gff", - "start": 78008, - "strand": "+", - "type": "gene" - }, - "OPG101": { - "end": 79019, - "seqid": "config/genemap.gff", - "start": 78486, - "strand": "+", - "type": "gene" - }, - "OPG102": { - "end": 80086, - "seqid": "config/genemap.gff", - "start": 79085, - "strand": "+", - "type": "gene" - }, - "OPG103": { - "end": 80558, - "seqid": "config/genemap.gff", - "start": 80001, - "strand": "+", - "type": "gene" - }, - "OPG104": { - "end": 81019, - "seqid": "config/genemap.gff", - "start": 80618, - "strand": "+", - "type": "gene" - }, - "OPG105": { - "end": 84986, - "seqid": "config/genemap.gff", - "start": 81126, - "strand": "+", - "type": "gene" - }, - "OPG106": { - "end": 85498, - "seqid": "config/genemap.gff", - "start": 84983, - "strand": "+", - "type": "gene" - }, - "OPG107": { - "end": 86081, - "seqid": "config/genemap.gff", - "start": 85512, - "strand": "+", - "type": "gene" - }, - "OPG108": { - "end": 87059, - "seqid": "config/genemap.gff", - "start": 86085, - "strand": "+", - "type": "gene" - }, - "OPG109": { - "end": 89447, - "seqid": "config/genemap.gff", - "start": 87060, - "strand": "+", - "type": "gene" - }, - "OPG110": { - "end": 90264, - "seqid": "config/genemap.gff", - "start": 89632, - "strand": "+", - "type": "gene" - }, - "OPG111": { - "end": 91209, - "seqid": "config/genemap.gff", - "start": 90265, - "strand": "+", - "type": "gene" - }, - "OPG112": { - "end": 91687, - "seqid": "config/genemap.gff", - "start": 91247, - "strand": "+", - "type": "gene" - }, - "OPG113": { - "end": 94268, - "seqid": "config/genemap.gff", - "start": 91731, - "strand": "+", - "type": "gene" - }, - "OPG114": { - "end": 94667, - "seqid": "config/genemap.gff", - "start": 94227, - "strand": "+", - "type": "gene" - }, - "OPG115": { - "end": 95361, - "seqid": "config/genemap.gff", - "start": 94660, - "strand": "+", - "type": "gene" - }, - "OPG116": { - "end": 96017, - "seqid": "config/genemap.gff", - "start": 95361, - "strand": "+", - "type": "gene" - }, - "OPG117": { - "end": 98406, - "seqid": "config/genemap.gff", - "start": 96049, - "strand": "+", - "type": "gene" - }, - "OPG118": { - "end": 100359, - "seqid": "config/genemap.gff", - "start": 98446, - "strand": "+", - "type": "gene" - }, - "OPG119": { - "end": 100871, - "seqid": "config/genemap.gff", - "start": 100386, - "strand": "+", - "type": "gene" - }, - "OPG120": { - "end": 101748, - "seqid": "config/genemap.gff", - "start": 100834, - "strand": "+", - "type": "gene" - }, - "OPG121": { - "end": 102431, - "seqid": "config/genemap.gff", - "start": 101790, - "strand": "+", - "type": "gene" - }, - "OPG122": { - "end": 103174, - "seqid": "config/genemap.gff", - "start": 102428, - "strand": "+", - "type": "gene" - }, - "OPG123": { - "end": 105070, - "seqid": "config/genemap.gff", - "start": 103175, - "strand": "+", - "type": "gene" - }, - "OPG124": { - "end": 105968, - "seqid": "config/genemap.gff", - "start": 105105, - "strand": "+", - "type": "gene" - }, - "OPG125": { - "end": 107654, - "seqid": "config/genemap.gff", - "start": 105999, - "strand": "+", - "type": "gene" - }, - "OPG126": { - "end": 108130, - "seqid": "config/genemap.gff", - "start": 107678, - "strand": "+", - "type": "gene" - }, - "OPG127": { - "end": 108825, - "seqid": "config/genemap.gff", - "start": 108151, - "strand": "+", - "type": "gene" - }, - "OPG128": { - "end": 109055, - "seqid": "config/genemap.gff", - "start": 108822, - "strand": "+", - "type": "gene" - }, - "OPG129": { - "end": 111004, - "seqid": "config/genemap.gff", - "start": 109070, - "strand": "+", - "type": "gene" - }, - "OPG130": { - "end": 111902, - "seqid": "config/genemap.gff", - "start": 111057, - "strand": "+", - "type": "gene" - }, - "OPG131": { - "end": 112425, - "seqid": "config/genemap.gff", - "start": 111940, - "strand": "+", - "type": "gene" - }, - "OPG132": { - "end": 113540, - "seqid": "config/genemap.gff", - "start": 112422, - "strand": "+", - "type": "gene" - }, - "OPG133": { - "end": 115696, - "seqid": "config/genemap.gff", - "start": 113564, - "strand": "+", - "type": "gene" - }, - "OPG134": { - "end": 116628, - "seqid": "config/genemap.gff", - "start": 115750, - "strand": "+", - "type": "gene" - }, - "OPG135": { - "end": 116911, - "seqid": "config/genemap.gff", - "start": 116609, - "strand": "+", - "type": "gene" - }, - "OPG136": { - "end": 119587, - "seqid": "config/genemap.gff", - "start": 116912, - "strand": "+", - "type": "gene" - }, - "OPG137": { - "end": 120558, - "seqid": "config/genemap.gff", - "start": 119602, - "strand": "+", - "type": "gene" - }, - "OPG138": { - "end": 121132, - "seqid": "config/genemap.gff", - "start": 120560, - "strand": "+", - "type": "gene" - }, - "OPG139": { - "end": 121368, - "seqid": "config/genemap.gff", - "start": 121156, - "strand": "+", - "type": "gene" - }, - "OPG140": { - "end": 121746, - "seqid": "config/genemap.gff", - "start": 121474, - "strand": "+", - "type": "gene" - }, - "OPG141": { - "end": 121924, - "seqid": "config/genemap.gff", - "start": 121763, - "strand": "+", - "type": "gene" - }, - "OPG142": { - "end": 122198, - "seqid": "config/genemap.gff", - "start": 121914, - "strand": "+", - "type": "gene" - }, - "OPG143": { - "end": 123315, - "seqid": "config/genemap.gff", - "start": 122182, - "strand": "+", - "type": "gene" - }, - "OPG144": { - "end": 123932, - "seqid": "config/genemap.gff", - "start": 123318, - "strand": "+", - "type": "gene" - }, - "OPG145": { - "end": 125425, - "seqid": "config/genemap.gff", - "start": 123947, - "strand": "+", - "type": "gene" - }, - "OPG146": { - "end": 125639, - "seqid": "config/genemap.gff", - "start": 125406, - "strand": "+", - "type": "gene" - }, - "OPG147": { - "end": 125987, - "seqid": "config/genemap.gff", - "start": 125640, - "strand": "+", - "type": "gene" - }, - "OPG148": { - "end": 127266, - "seqid": "config/genemap.gff", - "start": 125986, - "strand": "+", - "type": "gene" - }, - "OPG149": { - "end": 127759, - "seqid": "config/genemap.gff", - "start": 127196, - "strand": "+", - "type": "gene" - }, - "OPG150": { - "end": 128927, - "seqid": "config/genemap.gff", - "start": 127779, - "strand": "+", - "type": "gene" - }, - "OPG151": { - "end": 132418, - "seqid": "config/genemap.gff", - "start": 128924, - "strand": "+", - "type": "gene" - }, - "OPG153": { - "end": 137667, - "seqid": "config/genemap.gff", - "start": 136138, - "strand": "+", - "type": "gene" - }, - "OPG154": { - "end": 138050, - "seqid": "config/genemap.gff", - "start": 137718, - "strand": "+", - "type": "gene" - }, - "OPG155": { - "end": 138491, - "seqid": "config/genemap.gff", - "start": 138051, - "strand": "+", - "type": "gene" - }, - "OPG156": { - "end": 139409, - "seqid": "config/genemap.gff", - "start": 138492, - "strand": "+", - "type": "gene" - }, - "OPG157": { - "end": 139608, - "seqid": "config/genemap.gff", - "start": 139372, - "strand": "+", - "type": "gene" - }, - "OPG158": { - "end": 139769, - "seqid": "config/genemap.gff", - "start": 139641, - "strand": "+", - "type": "gene" - }, - "OPG159": { - "end": 140205, - "seqid": "config/genemap.gff", - "start": 139768, - "strand": "+", - "type": "gene" - }, - "OPG160": { - "end": 141074, - "seqid": "config/genemap.gff", - "start": 140172, - "strand": "+", - "type": "gene" - }, - "OPG161": { - "end": 141647, - "seqid": "config/genemap.gff", - "start": 141102, - "strand": "+", - "type": "gene" - }, - "OPG162": { - "end": 142158, - "seqid": "config/genemap.gff", - "start": 141652, - "strand": "+", - "type": "gene" - }, - "OPG163": { - "end": 142732, - "seqid": "config/genemap.gff", - "start": 142202, - "strand": "+", - "type": "gene" - }, - "OPG164": { - "end": 143464, - "seqid": "config/genemap.gff", - "start": 142778, - "strand": "+", - "type": "gene" - }, - "OPG165": { - "end": 144322, - "seqid": "config/genemap.gff", - "start": 143516, - "strand": "+", - "type": "gene" - }, - "OPG167": { - "end": 145407, - "seqid": "config/genemap.gff", - "start": 144574, - "strand": "+", - "type": "gene" - }, - "OPG170": { - "end": 146778, - "seqid": "config/genemap.gff", - "start": 146113, - "strand": "+", - "type": "gene" - }, - "OPG171": { - "end": 147389, - "seqid": "config/genemap.gff", - "start": 146988, - "strand": "+", - "type": "gene" - }, - "OPG172": { - "end": 148017, - "seqid": "config/genemap.gff", - "start": 147427, - "strand": "+", - "type": "gene" - }, - "OPG173": { - "end": 148261, - "seqid": "config/genemap.gff", - "start": 148037, - "strand": "+", - "type": "gene" - }, - "OPG174": { - "end": 149395, - "seqid": "config/genemap.gff", - "start": 148355, - "strand": "+", - "type": "gene" - }, - "OPG175": { - "end": 149819, - "seqid": "config/genemap.gff", - "start": 149442, - "strand": "+", - "type": "gene" - }, - "OPG176": { - "end": 150531, - "seqid": "config/genemap.gff", - "start": 149809, - "strand": "+", - "type": "gene" - }, - "OPG178": { - "end": 152123, - "seqid": "config/genemap.gff", - "start": 151509, - "strand": "+", - "type": "gene" - }, - "OPG180": { - "end": 154371, - "seqid": "config/genemap.gff", - "start": 152692, - "strand": "+", - "type": "gene" - }, - "OPG181": { - "end": 155416, - "seqid": "config/genemap.gff", - "start": 154412, - "strand": "+", - "type": "gene" - }, - "OPG185": { - "end": 159858, - "seqid": "config/genemap.gff", - "start": 158917, - "strand": "+", - "type": "gene" - }, - "OPG187": { - "end": 161533, - "seqid": "config/genemap.gff", - "start": 160622, - "strand": "+", - "type": "gene" - }, - "OPG188": { - "end": 163107, - "seqid": "config/genemap.gff", - "start": 161596, - "strand": "+", - "type": "gene" - }, - "OPG189": { - "end": 165018, - "seqid": "config/genemap.gff", - "start": 163333, - "strand": "+", - "type": "gene" - }, - "OPG190": { - "end": 166075, - "seqid": "config/genemap.gff", - "start": 165122, - "strand": "+", - "type": "gene" - }, - "OPG191": { - "end": 166667, - "seqid": "config/genemap.gff", - "start": 166161, - "strand": "+", - "type": "gene" - }, - "OPG192": { - "end": 167279, - "seqid": "config/genemap.gff", - "start": 166731, - "strand": "+", - "type": "gene" - }, - "OPG193": { - "end": 168137, - "seqid": "config/genemap.gff", - "start": 167334, - "strand": "+", - "type": "gene" - }, - "OPG195": { - "end": 168895, - "seqid": "config/genemap.gff", - "start": 168230, - "strand": "+", - "type": "gene" - }, - "OPG197": { - "end": 169972, - "seqid": "config/genemap.gff", - "start": 169670, - "strand": "+", - "type": "gene" - }, - "OPG198": { - "end": 170886, - "seqid": "config/genemap.gff", - "start": 170038, - "strand": "+", - "type": "gene" - }, - "OPG199": { - "end": 172022, - "seqid": "config/genemap.gff", - "start": 170988, - "strand": "+", - "type": "gene" - }, - "OPG200": { - "end": 172599, - "seqid": "config/genemap.gff", - "start": 172150, - "strand": "+", - "type": "gene" - }, - "OPG204": { - "end": 175587, - "seqid": "config/genemap.gff", - "start": 174532, - "strand": "+", - "type": "gene" - }, - "OPG205": { - "end": 178019, - "seqid": "config/genemap.gff", - "start": 175656, - "strand": "+", - "type": "gene" - }, - "OPG208": { - "end": 180339, - "seqid": "config/genemap.gff", - "start": 179266, - "strand": "+", - "type": "gene" - }, - "OPG209": { - "end": 181090, - "seqid": "config/genemap.gff", - "start": 180518, - "strand": "+", - "type": "gene" - }, - "OPG210": { - "end": 186998, - "seqid": "config/genemap.gff", - "start": 181356, - "strand": "+", - "type": "gene" - } - }, - "colorings": [ - { - "key": "clade_membership", - "title": "Clade", - "type": "categorical", - "scale": [ - [ - "IIb", - "#DEA73C" - ] - ] - }, - { - "key": "gt", - "title": "Genotype", - "type": "categorical" - }, - { - "key": "outbreak", - "title": "Outbreak", - "type": "categorical", - "scale": [ - [ - "hMPXV-1", - "#4C90C0" - ] - ] - }, - { - "key": "lineage", - "title": "Lineage", - "type": "categorical", - "scale": [ - [ - "B.1", - "#4041C7" - ], - [ - "B.1.1", - "#3F53CD" - ], - [ - "B.1.2", - "#4064CF" - ], - [ - "B.1.3", - "#4375CD" - ], - [ - "C.1", - "#4784C8" - ], - [ - "B.1.4", - "#4C91BF" - ], - [ - "B.1.5", - "#539CB4" - ], - [ - "B.1.6", - "#5AA5A7" - ], - [ - "B.1.7", - "#63AC9A" - ], - [ - "B.1.8", - "#6CB28C" - ], - [ - "B.1.9", - "#77B67E" - ], - [ - "B.1.10", - "#82BA71" - ], - [ - "B.1.11", - "#8FBC66" - ], - [ - "B.1.12", - "#9CBE5B" - ], - [ - "B.1.13", - "#A9BD53" - ], - [ - "B.1.14", - "#B5BD4C" - ], - [ - "B.1.15", - "#C1BA46" - ], - [ - "B.1.16", - "#CDB642" - ], - [ - "B.1.17", - "#D6B03F" - ], - [ - "B.1.18", - "#DEA73B" - ], - [ - "B.1.19", - "#E39B39" - ], - [ - "B.1.20", - "#E68D36" - ] - ] - }, - { - "key": "date", - "title": "Collection Date", - "type": "categorical" - }, - { - "key": "host", - "title": "Host", - "type": "categorical" - }, - { - "key": "strain", - "title": "Accession", - "type": "categorical" - }, - { - "key": "strain_original", - "title": "Strain name", - "type": "categorical" - }, - { - "key": "region", - "title": "Region", - "type": "categorical", - "scale": [ - [ - "Asia", - "#447CCD" - ], - [ - "Oceania", - "#5EA9A1" - ], - [ - "Africa", - "#8ABB6A" - ], - [ - "Europe", - "#BEBB48" - ], - [ - "South America", - "#E29E39" - ], - [ - "North America", - "#E2562B" - ] - ] - }, - { - "key": "country", - "title": "Country", - "type": "categorical", - "scale": [ - [ - "Israel", - "#5E1D9D" - ], - [ - "Taiwan", - "#3F45C8" - ], - [ - "South Korea", - "#3F51CC" - ], - [ - "Japan", - "#3E5CD0" - ], - [ - "Australia", - "#4067CF" - ], - [ - "South Africa", - "#6FB388" - ], - [ - "Portugal", - "#85BA6F" - ], - [ - "Ireland", - "#8DBC68" - ], - [ - "Spain", - "#95BD61" - ], - [ - "United Kingdom", - "#9DBE5A" - ], - [ - "France", - "#A5BE55" - ], - [ - "Belgium", - "#AEBD50" - ], - [ - "Netherlands", - "#B6BD4B" - ], - [ - "Switzerland", - "#BEBB48" - ], - [ - "Germany", - "#CDB642" - ], - [ - "Italy", - "#D3B240" - ], - [ - "Slovenia", - "#D8AE3E" - ], - [ - "Sweden", - "#DDA83C" - ], - [ - "Austria", - "#E1A13A" - ], - [ - "Czech Republic", - "#E49938" - ], - [ - "Slovakia", - "#E69036" - ], - [ - "Finland", - "#E68534" - ], - [ - "Brazil", - "#E56E30" - ], - [ - "Peru", - "#E3602D" - ], - [ - "Colombia", - "#E1522A" - ], - [ - "Mexico", - "#DF4428" - ], - [ - "USA", - "#DD3625" - ], - [ - "Canada", - "#DB2823" - ] - ] - } - ], - "filters": [ - "clade_membership", - "lineage", - "country", - "host", - "institution", - "region" - ], - "panels": [ - "tree", - "entropy" - ], - "extensions": { - "nextclade": { - "clade_node_attrs": [ - { - "name": "outbreak", - "displayName": "Outbreak" - }, - { - "name": "lineage", - "displayName": "Lineage" - } - ] - } - } - }, - "tree": { - "name": "NODE_0000001", - "node_attrs": { - "div": 0, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": {}, - "labels": { - "clade": "B.1" - } - }, - "children": [ - { - "name": "ref_in_coord", - "node_attrs": { - "div": 0, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000000", - "node_attrs": { - "div": 0, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T593-", - "T594-", - "T595-", - "C133164-", - "A133165-", - "A133166-", - "T133167-", - "C133168-", - "T133169-", - "T133170-", - "T133171-", - "C133172-", - "T133173-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A196601-", - "A196602-", - "A196603-" - ] - } - }, - "children": [ - { - "name": "MPX-42/Finland/2022", - "node_attrs": { - "div": 0, - "author": { - "author": "Kant,R., Smura,T., Vauhkonen,H., Vapalahti,O., Sironen,T.", - "value": "Kant,R., Smura,T., Vauhkonen,H., Vapalahti,O., Sironen,T." - }, - "strain_original": { - "value": "MPX-42/Finland/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Helsinki, Department of Virology, Faculty of Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON782022" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Finland" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-31" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - }, - { - "name": "CVR_MPXV1e", - "node_attrs": { - "div": 0, - "author": { - "author": "Filipe,A., Tong,L., Vattipally,S.B., Maclean,A., Gunson,R., Holden,M.T.G., Barr,D., Ho,A., Palmarini,M., Rambaut,A., Robertson,D.L., Thomson,E.C.", - "value": "Filipe,A., Tong,L., Vattipally,S.B., Maclean,A., Gunson,R., Holden,M.T.G., Barr,D., Ho,A., Palmarini,M., Rambaut,A., Robertson,D.L., Thomson,E.C." - }, - "strain_original": { - "value": "CVR_MPXV1e" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON808417" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-15" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133098-", - "T133099-", - "T133100-", - "T133101-", - "T133102-", - "C133103-", - "A136513-", - "T136514-", - "C136515-", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "4061", - "node_attrs": { - "div": 0, - "author": { - "author": "de la Hoz-Sanchez,B., Lopez-Ortiz,M., Gutierrez-Arroyo,A., Roces-Alvarez,P., Lazaro-Peona,F., Dahdouh,E., Bloise,I., Garcia-Rodriguez,J., Mingorance,J.", - "value": "de la Hoz-Sanchez,B., Lopez-Ortiz,M., Gutierrez-Arroyo,A., Roces-Alvarez,P., Lazaro-Peona,F., Dahdouh,E., Bloise,I., Garcia-Rodriguez,J., Mingorance,J." - }, - "strain_original": { - "value": "4061" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Hospital Universitario La Paz, Microbiology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON838940" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-20" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI024", - "node_attrs": { - "div": 0, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI024" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON694336" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A192404-", - "G192405-", - "T192406-", - "C192407-", - "A192408-", - "T192409-", - "A192410-", - "A192411-", - "G192412-", - "T192413-", - "T192414-", - "A192415-", - "G192416-", - "T192417-", - "T192418-", - "A192419-", - "A192420-", - "G192421-", - "T192422-", - "C192423-", - "A192424-", - "T192425-", - "A192426-", - "A192427-", - "G192428-", - "T192429-", - "T192430-", - "A192431-", - "G192432-", - "T192433-", - "T192434-", - "A192435-", - "A192436-", - "G192437-", - "T192438-", - "C192439-", - "A192440-", - "T192441-", - "A192442-", - "A192443-", - "G192444-", - "T192445-", - "T192446-", - "A192447-", - "G192448-", - "T192449-", - "T192450-", - "A192451-" - ] - } - } - }, - { - "name": "MPX_96X1Vd_9000217", - "node_attrs": { - "div": 0, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_96X1Vd_9000217" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415195" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-03-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV_USA_2022_IL001", - "node_attrs": { - "div": 0, - "author": { - "author": "Gigante,C.M., Ghinai,I., Seabolt,M.H., Zhao,H., Wilkins,K., Respress,J., Howard,D., Batra,D., McCollum,A., Hutson,C., Davidson,W., Rao,A., Kerins,J., Li,Y.", - "value": "Gigante,C.M., Ghinai,I., Seabolt,M.H., Zhao,H., Wilkins,K., Respress,J., Howard,D., Batra,D., McCollum,A., Hutson,C., Davidson,W., Rao,A., Kerins,J., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_IL001" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON959131" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "2022/2 SLO", - "node_attrs": { - "div": 0, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "strain_original": { - "value": "2022/2 SLO" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON631241" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-24" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPX/UZ_REGA_4/Belgium/2022", - "node_attrs": { - "div": 0, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPX/UZ_REGA_4/Belgium/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Rega Institute, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880420" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-27" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV_ISR001_2022", - "node_attrs": { - "div": 0, - "author": { - "author": "Israeli,O., Guedj-Dana,Y., Lazar,S., Shifman,O., Erez,N., Weiss,S., Paran,N., Israely,T., Schuster,O., Zvi,A., Beth-Din,A., Cohen Gihon,I.", - "value": "Israeli,O., Guedj-Dana,Y., Lazar,S., Shifman,O., Erez,N., Weiss,S., Paran,N., Israely,T., Schuster,O., Zvi,A., Beth-Din,A., Cohen Gihon,I." - }, - "strain_original": { - "value": "MPXV_ISR001_2022" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON649879" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Israel" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-20" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_107", - "node_attrs": { - "div": 0, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_107" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035713" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-28" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPX/human/USA/UT-UPHL-82200022/2022", - "node_attrs": { - "div": 0, - "author": { - "author": "Young,E.L., Hergert,J., Oakeson,K.F.", - "value": "Young,E.L., Hergert,J., Oakeson,K.F." - }, - "strain_original": { - "value": "MPX/human/USA/UT-UPHL-82200022/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Department of Health, Utah Public Health Laboratory, USA" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON627808" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-20" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - }, - { - "name": "CVR_MPXV1b", - "node_attrs": { - "div": 0, - "author": { - "author": "Filipe,A., Tong,L., Vattipally,S.B., Maclean,A., Gunson,R., Holden,M.T.G., Barr,D., Ho,A., Palmarini,M., Rambaut,A., Robertson,D.L., Thomson,E.C.", - "value": "Filipe,A., Tong,L., Vattipally,S.B., Maclean,A., Gunson,R., Holden,M.T.G., Barr,D., Ho,A., Palmarini,M., Rambaut,A., Robertson,D.L., Thomson,E.C." - }, - "strain_original": { - "value": "CVR_MPXV1b" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON808414" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-15" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133098-", - "T133099-", - "T133100-", - "T133101-", - "T133102-", - "C133103-", - "A136513-", - "T136514-", - "C136515-", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "hMPXV-IHU00003", - "node_attrs": { - "div": 0, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "strain_original": { - "value": "hMPXV-IHU00003" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP382480" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-04" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "hMPXV-IHU00005", - "node_attrs": { - "div": 0, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "strain_original": { - "value": "hMPXV-IHU00005" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP382482" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-04" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV_IRBA22-14", - "node_attrs": { - "div": 0, - "author": { - "author": "Jarjaval,F., Nolent,F., Criqui,A., Chapus,C., Lamer,O., Ferraris,O., Gorge,O.", - "value": "Jarjaval,F., Nolent,F., Criqui,A., Chapus,C., Lamer,O., Ferraris,O., Gorge,O." - }, - "strain_original": { - "value": "MPXV_IRBA22-14" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IRBA, D.DNRBC/D.2MI/U.BACT" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON755040" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-20" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI385", - "node_attrs": { - "div": 0, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI385" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP523987" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV/human/Japan/Tokyo/TKY220091/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/TKY220091/2022" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "LC722946" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Japan" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C13653T", - "C116100T", - "G150376A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG025": [ - "D539N" - ], - "OPG176": [ - "D190N" - ] - }, - "labels": { - "aa": "OPG025: D539N; OPG176: D190N" - } - } - }, - { - "name": "MPXV_USA_2022_MA001", - "node_attrs": { - "div": 0, - "author": { - "author": "Gigante,C.M., Smole,S., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Brown,C., Li,Y.", - "value": "Gigante,C.M., Smole,S., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Brown,C., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_MA001" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON563414" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV_2022_NL001", - "node_attrs": { - "div": 2, - "author": { - "author": "Oude Munnink,B.B., Boter,M., Wellers,B., Molenkamp,R., Sikkema,R.S., Koopmans,M.", - "value": "Oude Munnink,B.B., Boter,M., Wellers,B., Molenkamp,R., Sikkema,R.S., Koopmans,M." - }, - "strain_original": { - "value": "MPXV_2022_NL001" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Public Health Virology, Erasmus Medical Centre, The Netherlands" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON615424" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Netherlands" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G155611A", - "G171003A", - "A178777-", - "C178778-", - "A178779-", - "C178780-", - "G178781-", - "A178782-", - "A178783-", - "T178784-", - "A178785-", - "T178786-", - "G178787-", - "T178788-", - "A178789-", - "T178790-", - "G178791-", - "A178792-", - "C178793-", - "G178794-", - "G178795-", - "A178796-", - "T178797-", - "G178798-", - "G178799-", - "G178800-", - "A178801-", - "A178802-", - "T178803-", - "T178804-", - "G178805-", - "G178806-", - "T178807-", - "A178808-", - "A178809-", - "C178810-", - "G178811-", - "A178812-", - "T178813-", - "G178814-", - "A178815-", - "C178816-", - "A178817-", - "G178818-", - "A178819-", - "A178820-", - "A178821-", - "G178822-", - "C178823-", - "A178824-", - "G178825-", - "A178826-", - "T178827-", - "T178828-", - "G178829-", - "T178830-", - "C178831-", - "A178832-", - "G178833-", - "C178834-", - "T178835-", - "C178836-", - "T178837-", - "G178838-", - "C178839-", - "A178840-", - "T178841-", - "A178842-", - "C178843-", - "T178844-", - "A178845-", - "T178846-", - "T178847-", - "C178848-", - "T178849-", - "T178850-", - "C178851-", - "A178852-", - "T178853-", - "G178854-", - "A178855-", - "C178856-", - "A178857-", - "A178858-", - "T178859-", - "A178860-", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "-196603A" - ], - "OPG199": [ - "E6K" - ] - }, - "labels": { - "aa": "OPG199: E6K" - } - } - }, - { - "name": "MPXV-CH-38156923/2022", - "node_attrs": { - "div": 0, - "author": { - "author": "Laubscher,F., Schibler,M., Kaiser,L., Renzoni,A.", - "value": "Laubscher,F., Schibler,M., Kaiser,L., Renzoni,A." - }, - "strain_original": { - "value": "MPXV-CH-38156923/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Laboratory of Viorology, University Hospital of Geneva, Switzerland" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON622720" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Switzerland" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-24" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPxV/VIDRL01/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Hammerschlag,Y., MacLeod,G., Papadakis,G., Adnan Sanchez,A., Druce,J., Savic,I., Taiaroa,G., Roberts,J., Caly,L., Williamson,D.A., Cheng,A.C., McMahon,J.H.", - "value": "Hammerschlag,Y., MacLeod,G., Papadakis,G., Adnan Sanchez,A., Druce,J., Savic,I., Taiaroa,G., Roberts,J., Caly,L., Williamson,D.A., Cheng,A.C., McMahon,J.H." - }, - "strain_original": { - "value": "MPxV/VIDRL01/2022" - }, - "region": { - "value": "Oceania" - }, - "institution": { - "value": "Victorian Infectious Diseases Reference Laboratory, Doherty Institute, Australia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON631963" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Australia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C21128T", - "C133077T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196603A" - ], - "OPG037": [ - "E436K" - ] - }, - "labels": { - "aa": "OPG037: E436K" - } - } - }, - { - "name": "MPXV_USA_2021_MD", - "node_attrs": { - "div": 14, - "author": { - "author": "Gigante,C.M., Myers,R., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Blythe,D., Li,Y.", - "value": "Gigante,C.M., Myers,R., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Blythe,D., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2021_MD" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "strain": { - "value": "ON676708" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "outgroup" - }, - "date": { - "value": "2021-11-XX" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A3111G", - "T39139C", - "A73239G", - "A74205G", - "A77383G", - "C79348T", - "T84587C", - "C86979T", - "C133714T", - "T150469C", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C151461A", - "A155795G", - "C169722-", - "A169723-", - "G169724-", - "A169725-", - "T169726-", - "A169727-", - "A170262G", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "T183519C", - "T194099C" - ], - "OPG057": [ - "K353E" - ], - "OPG093": [ - "N88D" - ], - "OPG094": [ - "I142M" - ], - "OPG098": [ - "K162E" - ], - "OPG176": [ - "Y221H" - ], - "OPG197": [ - "S18X", - "D19-", - "T20X", - "*101X" - ], - "OPG210": [ - "S722P" - ] - }, - "labels": { - "aa": "OPG057: K353E; OPG093: N88D; OPG094: I142M; OPG098: K162E; OPG176: Y221H; OPG197: S18X, D19-, T20X, *101X; OPG210: S722P", - "clade": "outgroup" - } - } - }, - { - "name": "MPXV_GSTT_Patient1", - "node_attrs": { - "div": 0, - "author": { - "author": "Alcolea-Medina,A., Charalampous,T., Snell,L.B., Batra,R., Edgeworth,J.D.", - "value": "Alcolea-Medina,A., Charalampous,T., Snell,L.B., Batra,R., Edgeworth,J.D." - }, - "strain_original": { - "value": "MPXV_GSTT_Patient1" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Clinical Infection & Diagnostics Research, Kings College London, St Thomas Hospital, UK" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON645312" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-11" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "T597-", - "T598-", - "T599-", - "T600-", - "T601-", - "T602-", - "T617-", - "A2237-", - "C2238-", - "G2239-", - "C4693-", - "T4694-", - "T4695-", - "A4696-", - "A4697-", - "C4698-", - "T4699-", - "A4700-", - "A4701-", - "C4702-", - "T4703-", - "T4704-", - "A4705-", - "T4706-", - "G4707-", - "A4708-", - "C4709-", - "T4710-", - "T4711-", - "A4712-", - "A4713-", - "C4714-", - "T4715-", - "A4716-", - "A4717-", - "C4718-", - "T4719-", - "T4720-", - "A4721-", - "T4722-", - "G4723-", - "A4724-", - "C4725-", - "T4726-", - "T4727-", - "A4728-", - "A4729-", - "C4730-", - "T4731-", - "A4732-", - "A4733-", - "C4734-", - "T4735-", - "T4736-", - "A4737-", - "T4738-", - "G4739-", - "A4740-", - "C4741-", - "T4742-", - "T4743-", - "A4744-", - "A4745-", - "C4746-", - "T4747-", - "A4748-", - "A4749-", - "C4750-", - "T4751-", - "T4752-", - "A4753-", - "T4754-", - "G4755-", - "A4756-", - "C4757-", - "T4758-", - "T4759-", - "A4760-", - "A4761-", - "C4762-", - "T4763-", - "A4764-", - "A4765-", - "C4766-", - "T4767-", - "T4768-", - "A4769-", - "T4770-", - "G4771-", - "A4772-", - "C4773-", - "T4774-", - "T4775-", - "C6429-", - "T6430-", - "C7016-", - "T7017-", - "C7018-", - "T7019-", - "C7020-", - "G7021-", - "A7142-", - "T7143-", - "C7144-", - "T7145-", - "T7404-", - "A8048-", - "A8049-", - "T8325-", - "T8326-", - "A8419-", - "T8420-", - "A8421-", - "T8422-", - "A8471-", - "T8494-", - "T8913-", - "T8992-", - "A9282-", - "A9523-", - "A10274-", - "T10497-", - "A13276-", - "T13352-", - "T15546-", - "A15547-", - "A15867-", - "G16608-", - "T16609-", - "C16610-", - "A16611-", - "T16612-", - "C16613-", - "A18055-", - "C18056-", - "C18057-", - "A21075-", - "A23167-", - "A24307-", - "C24336-", - "A27108-", - "A28524-", - "A28525-", - "A28583-", - "T28584-", - "T28585-", - "A28586-", - "T28587-", - "C28588-", - "C28589-", - "A28590-", - "G28591-", - "T28592-", - "G28593-", - "T28594-", - "T28595-", - "A28596-", - "A28597-", - "A28598-", - "A28599-", - "A28600-", - "A28601-", - "T32188-", - "G32209-", - "A32210-", - "C32211-", - "A33193-", - "T33409-", - "T35565-", - "T41738-", - "T41929-", - "A43495-", - "A45117-", - "A46506-", - "C46507-", - "A46508-", - "T46590-", - "T46643-", - "A47573-", - "A47700-", - "C47701-", - "T48162-", - "A48163-", - "G48164-", - "T50499-", - "C50500-", - "T50575-", - "A50576-", - "A57274-", - "A58644-", - "A62034-", - "T62369-", - "T64749-", - "T66777-", - "A66839-", - "A71174-", - "T71896-", - "T76079-", - "T76080-", - "A76883-", - "T80841-", - "T80842-", - "A81968-", - "T87399-", - "T88831-", - "A89100-", - "A91698-", - "T94640-", - "T94641-", - "T97549-", - "T102743-", - "T103362-", - "T105355-", - "C106158-", - "C115266-", - "T116958-", - "T121116-", - "A123988-", - "A124720-", - "A127747-", - "A127748-", - "A128927-", - "G131761-", - "T132811-", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "T133084-", - "T133085-", - "T133086-", - "T133087-", - "T133088-", - "T133089-", - "T133090-", - "T133091-", - "T133092-", - "T133493-", - "C133494-", - "G133495-", - "G133496-", - "T133497-", - "C133498-", - "C133499-", - "A133500-", - "T133501-", - "G133502-", - "T133503-", - "C133504-", - "T133505-", - "C133506-", - "C133507-", - "A133508-", - "T133509-", - "T133510-", - "G133511-", - "C133512-", - "T133513-", - "A133514-", - "C133515-", - "A133516-", - "C133517-", - "C133518-", - "A133519-", - "C133520-", - "C133521-", - "A133522-", - "T133523-", - "T133524-", - "A133525-", - "G133526-", - "A133527-", - "T133528-", - "T133529-", - "T133530-", - "A133531-", - "C133532-", - "A133533-", - "G133534-", - "G133535-", - "C133536-", - "T133537-", - "G133538-", - "C133539-", - "T133540-", - "A133541-", - "G133542-", - "T133543-", - "T133544-", - "G133545-", - "T133546-", - "C133547-", - "G133548-", - "T133549-", - "T133550-", - "C133551-", - "G133552-", - "A133553-", - "G133554-", - "A133555-", - "T133556-", - "C133557-", - "A133558-", - "G133559-", - "A133560-", - "A133561-", - "A133562-", - "T133563-", - "A133564-", - "C133565-", - "G133566-", - "T133567-", - "G133568-", - "T133569-", - "T133570-", - "T133571-", - "T133572-", - "C133573-", - "T133574-", - "T133575-", - "G133576-", - "G133577-", - "A133578-", - "A133579-", - "T133580-", - "G133581-", - "G133582-", - "A133583-", - "T133584-", - "T133585-", - "T133586-", - "C133587-", - "G133588-", - "T133589-", - "C133590-", - "G133591-", - "A133592-", - "T133593-", - "G133594-", - "T133595-", - "A133596-", - "C133597-", - "T133598-", - "T133599-", - "G133600-", - "T133601-", - "C133602-", - "A133603-", - "T133604-", - "G133605-", - "A133606-", - "T133607-", - "T133608-", - "G133609-", - "G133610-", - "C133611-", - "A133612-", - "T133613-", - "C133614-", - "G133615-", - "A133616-", - "A133617-", - "A133618-", - "C133619-", - "A133620-", - "C133621-", - "T133622-", - "T133623-", - "A133624-", - "T133625-", - "T133626-", - "A133627-", - "A133628-", - "G133629-", - "T133630-", - "T133631-", - "C133632-", - "T133633-", - "T133634-", - "T133635-", - "T133636-", - "T133637-", - "T133638-", - "T133639-", - "C133640-", - "A133641-", - "A133642-", - "T133643-", - "T133644-", - "C133645-", - "T133646-", - "A133647-", - "C133648-", - "G133649-", - "A133650-", - "T133651-", - "T133652-", - "T133653-", - "T133654-", - "A133655-", - "T133656-", - "T133657-", - "T133658-", - "C133659-", - "T133660-", - "T133661-", - "T133662-", - "C133663-", - "G133664-", - "C133665-", - "G133666-", - "A133667-", - "G133668-", - "T133669-", - "C133670-", - "A133671-", - "A133672-", - "T133673-", - "T133674-", - "C133675-", - "C133676-", - "C133677-", - "T133678-", - "C133679-", - "C133680-", - "T133681-", - "G133682-", - "T133683-", - "A133684-", - "G133685-", - "T133686-", - "A133687-", - "A133688-", - "C133689-", - "T133690-", - "A133691-", - "T133692-", - "C133693-", - "A133694-", - "G133695-", - "T133696-", - "T133697-", - "T133698-", - "T133699-", - "G133700-", - "T133701-", - "C133702-", - "A133703-", - "G133704-", - "A133705-", - "T133706-", - "T133707-", - "C133708-", - "A133709-", - "C133710-", - "G133711-", - "C133712-", - "T133713-", - "C133714-", - "T133715-", - "C133716-", - "T133717-", - "A133718-", - "C133719-", - "G133720-", - "T133721-", - "A133722-", - "G133723-", - "A133724-", - "C133725-", - "T133726-", - "T133727-", - "T133728-", - "C133729-", - "T133730-", - "T133731-", - "G133732-", - "T133733-", - "A133734-", - "A133735-", - "G133736-", - "T133737-", - "T133738-", - "A133739-", - "C133740-", - "T133741-", - "A133742-", - "A133743-", - "T133744-", - "T133745-", - "T133746-", - "G133747-", - "T133748-", - "T133749-", - "C133750-", - "C133751-", - "C133752-", - "T133753-", - "G133754-", - "G133755-", - "C133756-", - "A133757-", - "T133758-", - "T133759-", - "A133760-", - "C133761-", - "C133762-", - "G133763-", - "A133764-", - "G133765-", - "T133766-", - "T133767-", - "C133768-", - "A133769-", - "G133770-", - "T133771-", - "T133772-", - "T133773-", - "T133774-", - "A133775-", - "T133776-", - "A133777-", - "T133778-", - "G133779-", - "C133780-", - "C133781-", - "G133782-", - "A133783-", - "A133784-", - "T133785-", - "A133786-", - "G133787-", - "A133788-", - "G133789-", - "T133790-", - "T133791-", - "C133792-", - "T133793-", - "G133794-", - "A133795-", - "T133796-", - "T133797-", - "C133798-", - "A133799-", - "T133800-", - "C133801-", - "C133802-", - "T133803-", - "T133804-", - "T133805-", - "G133806-", - "A133807-", - "G133808-", - "A133809-", - "A133810-", - "G133811-", - "A133812-", - "T133813-", - "C133814-", - "T133815-", - "C133816-", - "T133817-", - "A133818-", - "G133819-", - "C133820-", - "G133821-", - "A133822-", - "T133823-", - "C133824-", - "G133825-", - "T133826-", - "T133827-", - "C133828-", - "A133829-", - "A133830-", - "G133831-", - "A133832-", - "T133833-", - "C133834-", - "C133835-", - "C133836-", - "T133837-", - "G133838-", - "A133839-", - "T133840-", - "T133841-", - "C133842-", - "T133843-", - "A133844-", - "G133845-", - "T133846-", - "C133847-", - "T133848-", - "T133849-", - "T133850-", - "A133851-", - "G133852-", - "C133853-", - "C133854-", - "T133855-", - "A133856-", - "T133857-", - "T133858-", - "T133859-", - "A133860-", - "C133861-", - "C133862-", - "T133863-", - "C133864-", - "C133865-", - "T133866-", - "C133867-", - "A133868-", - "G133869-", - "A133870-", - "A133871-", - "G133872-", - "A133873-", - "T133874-", - "G133875-", - "C133876-", - "T133877-", - "C133878-", - "C133879-", - "G133880-", - "T133881-", - "T133882-", - "A133883-", - "C133884-", - "C133885-", - "G133886-", - "T133887-", - "T133888-", - "T133889-", - "T133890-", - "T133891-", - "A133892-", - "C133893-", - "A133894-", - "A133895-", - "T133896-", - "C133897-", - "G133898-", - "T133899-", - "T133900-", - "A133901-", - "A133902-", - "G133903-", - "A133904-", - "T133905-", - "G133906-", - "T133907-", - "C133908-", - "T133909-", - "A133910-", - "T133911-", - "C133912-", - "A133913-", - "A133914-", - "G133915-", - "A133916-", - "T133917-", - "C133918-", - "C133919-", - "A133920-", - "T133921-", - "G133922-", - "A133923-", - "T133924-", - "T133925-", - "C133926-", - "T133927-", - "A133928-", - "T133929-", - "C133930-", - "T133931-", - "C133932-", - "T133933-", - "T133934-", - "T133935-", - "T133936-", - "C133937-", - "C133938-", - "A133939-", - "T133940-", - "A133941-", - "T133942-", - "C133943-", - "A133944-", - "G133945-", - "T137881-", - "A138468-", - "T139424-", - "G139425-", - "T139426-", - "A140105-", - "T140106-", - "A140107-", - "A140108-", - "C140109-", - "A140110-", - "A140111-", - "T140112-", - "T140113-", - "A142752-", - "G143458-", - "A145892-", - "T145976-", - "A145977-", - "A145978-", - "C146084-", - "G146085-", - "T146127-", - "T146860-", - "A146861-", - "T146869-", - "A146870-", - "T146871-", - "T146872-", - "T146873-", - "T146874-", - "A146875-", - "T146876-", - "A146877-", - "T146878-", - "T146879-", - "T146880-", - "A146964-", - "A148136-", - "A148206-", - "T148337-", - "T150532-", - "A151015-", - "T151016-", - "G151017-", - "A151018-", - "C151019-", - "A151042-", - "T152265-", - "T152266-", - "A152267-", - "A152668-", - "A152669-", - "A153418-", - "T154351-", - "C154352-", - "T155417-", - "A156206-", - "T156370-", - "T156371-", - "A156372-", - "C156373-", - "T156374-", - "G156375-", - "A156376-", - "C156377-", - "T156378-", - "A156379-", - "C156380-", - "A156381-", - "T156382-", - "G156383-", - "T156384-", - "A156385-", - "C156386-", - "T156387-", - "A156388-", - "T156389-", - "T156390-", - "T156391-", - "T156392-", - "A156393-", - "C156394-", - "A156395-", - "T156396-", - "T156397-", - "A156398-", - "C156399-", - "T156400-", - "A156401-", - "C156402-", - "A156403-", - "T156404-", - "T156405-", - "G156406-", - "G156407-", - "C156408-", - "T156409-", - "A156410-", - "C156411-", - "G156412-", - "G156413-", - "C156414-", - "A156415-", - "T156416-", - "A156417-", - "T156418-", - "A156419-", - "T156420-", - "A156421-", - "C156422-", - "C156423-", - "T156424-", - "A156425-", - "T156426-", - "T156427-", - "T156428-", - "C156429-", - "G156430-", - "T156431-", - "C156432-", - "A156433-", - "C156434-", - "T156435-", - "T156436-", - "C156437-", - "C156438-", - "A156439-", - "C156440-", - "A156441-", - "C156442-", - "G156443-", - "C156444-", - "T156445-", - "C156446-", - "C156447-", - "G156448-", - "G156449-", - "T156450-", - "A156451-", - "A156452-", - "A156453-", - "C156454-", - "G156455-", - "G156456-", - "G156457-", - "T156458-", - "G156459-", - "T156460-", - "C156461-", - "A156462-", - "T156463-", - "G156464-", - "T156465-", - "G156466-", - "A156467-", - "C156468-", - "G156469-", - "A156470-", - "G156471-", - "G156472-", - "G156473-", - "A156474-", - "G156475-", - "A156476-", - "A156477-", - "T156478-", - "C156479-", - "T156480-", - "T156481-", - "G156482-", - "A156483-", - "T156484-", - "A156485-", - "A156486-", - "G156487-", - "A156488-", - "G156489-", - "G156490-", - "C156491-", - "A156492-", - "T156493-", - "A156494-", - "A156495-", - "T156496-", - "C156497-", - "A156498-", - "A156499-", - "T156500-", - "G156501-", - "T156502-", - "T156503-", - "G156504-", - "T156505-", - "A156506-", - "A156507-", - "T156508-", - "C156509-", - "C156510-", - "G156511-", - "A156512-", - "T156513-", - "G156514-", - "T156515-", - "C156516-", - "C156517-", - "A156518-", - "C156519-", - "C156520-", - "T156521-", - "G156522-", - "G156523-", - "A156524-", - "G156525-", - "A156526-", - "A156527-", - "T156528-", - "T156529-", - "T156530-", - "G156531-", - "C156532-", - "C156533-", - "A156534-", - "A156535-", - "G156536-", - "G156537-", - "T156538-", - "C156539-", - "A156540-", - "G156541-", - "A156542-", - "T156543-", - "G156544-", - "T156545-", - "A156546-", - "G156547-", - "A156548-", - "G156549-", - "T156550-", - "T156551-", - "G156552-", - "G156553-", - "T156554-", - "A156555-", - "G156556-", - "T156557-", - "G156558-", - "A156559-", - "T156560-", - "A156561-", - "A156562-", - "C156563-", - "A156564-", - "C156565-", - "A156566-", - "A156567-", - "A156568-", - "A156569-", - "T156570-", - "G156571-", - "T156572-", - "G156573-", - "A156574-", - "A156575-", - "C156576-", - "A156577-", - "C156578-", - "T156579-", - "G156580-", - "C156581-", - "C156582-", - "C156583-", - "A156584-", - "C156585-", - "C156586-", - "T156587-", - "C156588-", - "A156589-", - "T156590-", - "A156591-", - "C156592-", - "A156593-", - "T156594-", - "A156595-", - "T156596-", - "A156597-", - "C156598-", - "C156599-", - "G156600-", - "C156601-", - "A156602-", - "A156603-", - "T156604-", - "C156605-", - "C156606-", - "C156607-", - "C156608-", - "A156609-", - "A156610-", - "T156611-", - "T156612-", - "A156613-", - "T156614-", - "T156615-", - "C156616-", - "T156617-", - "A156618-", - "A156619-", - "T156620-", - "A156621-", - "G156622-", - "A156623-", - "T156624-", - "G156625-", - "T156626-", - "C156627-", - "A156628-", - "T156629-", - "C156630-", - "A156631-", - "A156632-", - "T156633-", - "G156634-", - "T156635-", - "A156636-", - "G156637-", - "A156638-", - "A156639-", - "A156640-", - "A156641-", - "T156642-", - "G156643-", - "C156644-", - "C156645-", - "C156646-", - "A156647-", - "A156648-", - "C156649-", - "A156650-", - "G156651-", - "G156652-", - "A156653-", - "T156654-", - "C156655-", - "A156656-", - "T156657-", - "T156658-", - "T156659-", - "G156660-", - "A156661-", - "T156662-", - "A156663-", - "A156664-", - "G156665-", - "G156666-", - "T156667-", - "A156668-", - "A156669-", - "A156670-", - "G156671-", - "T156672-", - "G156673-", - "T156674-", - "A156675-", - "C156676-", - "C156677-", - "G156678-", - "G156679-", - "A156680-", - "A156681-", - "C156682-", - "A156683-", - "C156684-", - "A156685-", - "G156686-", - "A156687-", - "A156688-", - "C156689-", - "A156690-", - "A156691-", - "A156692-", - "T156693-", - "G156694-", - "T156695-", - "T156696-", - "C156697-", - "G156698-", - "T156699-", - "G156700-", - "T156701-", - "C156702-", - "A156703-", - "T156704-", - "C156705-", - "C156706-", - "T156707-", - "G156708-", - "G156709-", - "T156710-", - "T156711-", - "G156712-", - "G156713-", - "T156714-", - "A156715-", - "T156716-", - "A156717-", - "C156718-", - "G156719-", - "C156720-", - "T156721-", - "A156722-", - "C156723-", - "T156724-", - "G156725-", - "A156726-", - "T156727-", - "T156728-", - "C156729-", - "T156730-", - "T156731-", - "C156732-", - "A156733-", - "C156734-", - "A156735-", - "G156736-", - "A156737-", - "C156738-", - "T156739-", - "G156740-", - "A156741-", - "A156742-", - "G156743-", - "A156744-", - "T156745-", - "T156746-", - "G156747-", - "T156748-", - "C156749-", - "G156750-", - "A156751-", - "G156752-", - "A156753-", - "T156754-", - "T156755-", - "T156756-", - "G156757-", - "T156758-", - "G156759-", - "T156760-", - "A156761-", - "C156762-", - "C156763-", - "A156764-", - "A156765-", - "A156766-", - "A156767-", - "A156768-", - "A156769-", - "G156770-", - "G156771-", - "A156772-", - "G156773-", - "A156774-", - "T156775-", - "G156776-", - "T156777-", - "C156778-", - "C156779-", - "A156780-", - "T156781-", - "G156782-", - "C156783-", - "G156784-", - "G156785-", - "A156786-", - "T156787-", - "A156788-", - "C156789-", - "T156790-", - "T156791-", - "T156792-", - "G156793-", - "G156794-", - "T156795-", - "G156796-", - "G156797-", - "A156798-", - "A156799-", - "T156800-", - "A156801-", - "G156802-", - "A156803-", - "T156804-", - "G156805-", - "A156806-", - "A156807-", - "G156808-", - "G156809-", - "A156810-", - "A156811-", - "A156812-", - "T156813-", - "C156814-", - "C156815-", - "T156816-", - "A156817-", - "T156818-", - "T156819-", - "T156820-", - "G156821-", - "T156822-", - "A156823-", - "A156824-", - "A156825-", - "T156826-", - "C156827-", - "G156828-", - "T156829-", - "G156830-", - "T156831-", - "T156832-", - "G156833-", - "T156834-", - "G156835-", - "T156836-", - "T156837-", - "G156838-", - "G156839-", - "T156840-", - "G156841-", - "A156842-", - "A156843-", - "T156844-", - "A156845-", - "T156846-", - "T156847-", - "G156848-", - "C156849-", - "G156850-", - "A156851-", - "C156852-", - "T156853-", - "A156854-", - "C156855-", - "C156856-", - "T156857-", - "A156858-", - "C156859-", - "G156860-", - "T156861-", - "A156862-", - "A156863-", - "T156864-", - "T156865-", - "A156866-", - "T156867-", - "A156868-", - "G156869-", - "A156870-", - "C156871-", - "T156872-", - "T156873-", - "G156874-", - "A156875-", - "T156876-", - "C156877-", - "C156878-", - "A156879-", - "T156880-", - "T156881-", - "T156882-", - "C156883-", - "C156884-", - "T156885-", - "C156886-", - "C156887-", - "A156888-", - "T156889-", - "G156890-", - "C156891-", - "A156892-", - "A156893-", - "A156894-", - "C156895-", - "T156896-", - "A156897-", - "T156898-", - "C156899-", - "T156900-", - "A156901-", - "T156902-", - "C156903-", - "T156904-", - "A156905-", - "A156906-", - "A156907-", - "T156908-", - "G156909-", - "T156910-", - "A156911-", - "A156912-", - "T156913-", - "T156914-", - "A156915-", - "A156916-", - "T156917-", - "T156918-", - "A156919-", - "T156920-", - "G156921-", - "A156922-", - "T156923-", - "T156924-", - "T156925-", - "T156926-", - "G156927-", - "A156928-", - "T156929-", - "G156930-", - "A156931-", - "T156932-", - "A156933-", - "A156934-", - "T156935-", - "G156936-", - "T156937-", - "T156938-", - "A156939-", - "C156940-", - "C156941-", - "A156942-", - "T156943-", - "A156944-", - "C156945-", - "A156946-", - "T156947-", - "T156948-", - "A156949-", - "T156950-", - "A156951-", - "T156952-", - "C156953-", - "A156954-", - "C156955-", - "T156956-", - "A156957-", - "C156958-", - "T156959-", - "T156960-", - "G156961-", - "G156962-", - "T156963-", - "T156964-", - "A156965-", - "G156966-", - "T156967-", - "G156968-", - "T156969-", - "G156970-", - "T156971-", - "A156972-", - "T156973-", - "T156974-", - "A156975-", - "T156976-", - "T156977-", - "T156978-", - "A156979-", - "G156980-", - "T156981-", - "A156982-", - "T156983-", - "G156984-", - "G156985-", - "A156986-", - "A156987-", - "G156988-", - "A156989-", - "C156990-", - "C156991-", - "T156992-", - "A156993-", - "T156994-", - "T156995-", - "A156996-", - "A156997-", - "T156998-", - "A156999-", - "A157000-", - "T157001-", - "T157002-", - "A157003-", - "C157004-", - "T157005-", - "T157006-", - "A157007-", - "T157008-", - "C157009-", - "T157010-", - "T157011-", - "T157012-", - "T157013-", - "G157014-", - "A157015-", - "C157016-", - "G157017-", - "A157018-", - "T157019-", - "C157020-", - "T157021-", - "T157022-", - "G157023-", - "T157024-", - "T157025-", - "A157026-", - "T157027-", - "A157028-", - "A157029-", - "T157030-", - "T157031-", - "A157032-", - "T157033-", - "A157034-", - "A157035-", - "T157036-", - "A157037-", - "T157038-", - "A157039-", - "A157040-", - "A157041-", - "A157042-", - "A157043-", - "T157044-", - "A157045-", - "C157046-", - "T157047-", - "T157048-", - "A157049-", - "T157050-", - "G157051-", - "A157052-", - "C157053-", - "A157054-", - "T157055-", - "A157056-", - "G157057-", - "T157058-", - "A157059-", - "A157060-", - "C157061-", - "T157062-", - "C157063-", - "A157064-", - "T157065-", - "A157066-", - "A157067-", - "T157068-", - "T157069-", - "G157070-", - "C157071-", - "T157072-", - "G157073-", - "A157074-", - "C157075-", - "G157076-", - "C157077-", - "G157078-", - "A157079-", - "T157080-", - "A157081-", - "A157082-", - "A157083-", - "T157084-", - "T157085-", - "C157086-", - "G157087-", - "T157088-", - "A157089-", - "A157090-", - "T157091-", - "A157092-", - "A157093-", - "T157094-", - "C157095-", - "T157096-", - "G157097-", - "T157098-", - "T157099-", - "T157100-", - "T157101-", - "G157102-", - "T157103-", - "T157104-", - "C157105-", - "A157106-", - "A157107-", - "A157108-", - "T157109-", - "T157110-", - "T157111-", - "T157112-", - "T157113-", - "A157114-", - "T157115-", - "A157116-", - "A157117-", - "G157118-", - "G157119-", - "A157120-", - "A157121-", - "T157122-", - "C157123-", - "T157124-", - "A157125-", - "C157126-", - "A157127-", - "G157128-", - "G157129-", - "C157130-", - "A157131-", - "T157132-", - "A157133-", - "A157134-", - "A157135-", - "A157136-", - "A157137-", - "T157138-", - "A157139-", - "A157140-", - "A157141-", - "A157142-", - "A157143-", - "T157144-", - "A157145-", - "T157146-", - "A157147-", - "A157148-", - "T157149-", - "C157150-", - "T157151-", - "A157152-", - "T157153-", - "A157154-", - "A157155-", - "T157156-", - "A157157-", - "T157158-", - "A157159-", - "C157160-", - "T157161-", - "C157162-", - "T157163-", - "T157164-", - "A157165-", - "C157166-", - "A157167-", - "A157168-", - "C157169-", - "G157170-", - "C157171-", - "C157172-", - "A157173-", - "T157174-", - "C157175-", - "A157176-", - "T157177-", - "G157178-", - "A157179-", - "A157180-", - "T157181-", - "A157182-", - "G157183-", - "C157184-", - "A157185-", - "G157186-", - "T157187-", - "G157188-", - "A157189-", - "A157190-", - "T157191-", - "T157192-", - "A157193-", - "A157194-", - "T157195-", - "T157196-", - "G157197-", - "C157198-", - "T157199-", - "G157200-", - "T157201-", - "T157202-", - "A157203-", - "T157204-", - "T157205-", - "A157206-", - "T157207-", - "G157208-", - "G157209-", - "A157210-", - "T157211-", - "T157212-", - "T157213-", - "A157214-", - "G157215-", - "A157216-", - "A157217-", - "A157218-", - "T157219-", - "A157220-", - "G157221-", - "T157222-", - "G157223-", - "G157224-", - "A157225-", - "C157226-", - "G157227-", - "A157228-", - "T157229-", - "T157230-", - "T157231-", - "T157232-", - "G157233-", - "T157234-", - "G157235-", - "A157236-", - "T157237-", - "A157238-", - "T157239-", - "T157240-", - "A157241-", - "A157242-", - "T157243-", - "A157244-", - "T157245-", - "A157246-", - "G157247-", - "T157248-", - "T157249-", - "A157250-", - "T157251-", - "T157252-", - "A157253-", - "A157254-", - "T157255-", - "G157256-", - "A157257-", - "T157258-", - "G157259-", - "A157260-", - "A157261-", - "A157262-", - "G157263-", - "G157264-", - "A157265-", - "T157266-", - "A157267-", - "A157268-", - "A157269-", - "C157270-", - "G157271-", - "C157272-", - "G157273-", - "C157274-", - "A157275-", - "T157276-", - "A157277-", - "G157278-", - "A157279-", - "C157280-", - "T157281-", - "C157282-", - "A157283-", - "T157284-", - "C157285-", - "C157286-", - "T157287-", - "A157288-", - "T157289-", - "C157290-", - "T157291-", - "G157292-", - "G157293-", - "A157294-", - "G157295-", - "C157296-", - "C157297-", - "T157298-", - "C157299-", - "C157300-", - "G157301-", - "A157302-", - "A157303-", - "T157304-", - "A157305-", - "T157306-", - "T157307-", - "T157308-", - "T157309-", - "T157310-", - "T157311-", - "C157312-", - "C157313-", - "A157314-", - "T157315-", - "T157316-", - "C157317-", - "T157318-", - "G157319-", - "T157320-", - "T157321-", - "T157322-", - "T157323-", - "C157324-", - "C157325-", - "A157326-", - "A157327-", - "T157328-", - "A157329-", - "A157330-", - "T157331-", - "T157332-", - "T157333-", - "T157334-", - "A157335-", - "T157336-", - "C157337-", - "G157338-", - "A157339-", - "T157340-", - "T157341-", - "C157342-", - "T157343-", - "A157344-", - "A157345-", - "T157346-", - "G157347-", - "A157348-", - "A157349-", - "T157350-", - "A157351-", - "C157352-", - "G157353-", - "A157354-", - "A157355-", - "G157356-", - "T157357-", - "T157358-", - "A157359-", - "A157360-", - "T157361-", - "C157362-", - "T157363-", - "A157364-", - "A157365-", - "G157366-", - "T157367-", - "C157368-", - "A157369-", - "T157370-", - "T157371-", - "T157372-", - "A157373-", - "G157374-", - "A157375-", - "T157376-", - "T157377-", - "A157378-", - "T157379-", - "C157380-", - "A157381-", - "A157382-", - "A157383-", - "G157384-", - "T157385-", - "G157386-", - "T157387-", - "T157388-", - "A157389-", - "A157390-", - "C157391-", - "T157392-", - "A157393-", - "T157394-", - "T157395-", - "T157396-", - "G157397-", - "A157398-", - "T157399-", - "C157400-", - "G157401-", - "A157402-", - "T157403-", - "T157404-", - "A157405-", - "C157406-", - "A157407-", - "T157408-", - "T157409-", - "T157410-", - "A157411-", - "T157412-", - "G157413-", - "G157414-", - "G157415-", - "A157416-", - "T157417-", - "A157418-", - "C157419-", - "C157420-", - "T157421-", - "T157422-", - "T157423-", - "G157424-", - "A157425-", - "G157426-", - "C157427-", - "C157428-", - "T157429-", - "A157430-", - "A157431-", - "C157432-", - "T157433-", - "A157434-", - "A157435-", - "C157436-", - "A157437-", - "A157438-", - "T157439-", - "A157440-", - "A157441-", - "C157442-", - "G157443-", - "T157444-", - "G157445-", - "A157446-", - "A157447-", - "A157448-", - "T157449-", - "A157450-", - "T157451-", - "A157452-", - "T157453-", - "T157454-", - "C157455-", - "T157456-", - "T157457-", - "T157458-", - "C157459-", - "A157460-", - "A157461-", - "C157462-", - "C157463-", - "G157464-", - "C157465-", - "T157466-", - "G157467-", - "A157468-", - "T157469-", - "T157470-", - "T157471-", - "T157472-", - "T157473-", - "T157474-", - "T157475-", - "A157476-", - "C157477-", - "A157478-", - "A157479-", - "A157480-", - "T157481-", - "T157482-", - "G157483-", - "G157484-", - "A157485-", - "T157486-", - "C157487-", - "T157488-", - "G157489-", - "T157490-", - "C157491-", - "A157492-", - "T157493-", - "T157494-", - "A157495-", - "C157496-", - "T157497-", - "G157498-", - "A157499-", - "G157500-", - "T157501-", - "G157502-", - "C157503-", - "G157504-", - "A157505-", - "A157506-", - "A157507-", - "A157508-", - "A157509-", - "T157510-", - "A157511-", - "C157512-", - "A157513-", - "T157514-", - "A157515-", - "C157516-", - "T157517-", - "T157518-", - "A157519-", - "A157520-", - "A157521-", - "A157522-", - "A157523-", - "T157524-", - "C157525-", - "T157526-", - "T157527-", - "T157528-", - "G157529-", - "T157530-", - "T157531-", - "T157532-", - "T157533-", - "A157534-", - "G157535-", - "A157536-", - "A157537-", - "A157538-", - "C157539-", - "T157540-", - "G157541-", - "T157542-", - "A157543-", - "T157544-", - "C157545-", - "G157546-", - "A157547-", - "T157548-", - "T157549-", - "T157550-", - "C157551-", - "T157552-", - "A157553-", - "C157554-", - "A157555-", - "T157556-", - "A157557-", - "T157558-", - "A157559-", - "C157560-", - "G157561-", - "C157562-", - "T157563-", - "G157564-", - "A157565-", - "T157566-", - "A157567-", - "A157568-", - "A157569-", - "T157570-", - "A157571-", - "T157572-", - "A157573-", - "A157574-", - "T157575-", - "A157576-", - "A157577-", - "C157578-", - "A157579-", - "A157580-", - "G157581-", - "A157582-", - "A157583-", - "A157584-", - "A157585-", - "T157586-", - "A157587-", - "G157588-", - "A157589-", - "A157590-", - "T157591-", - "T157592-", - "A157593-", - "G157594-", - "C157595-", - "A157596-", - "T157597-", - "C157598-", - "G157599-", - "T157600-", - "T157601-", - "T157602-", - "A157603-", - "A157604-", - "C157605-", - "A157606-", - "C157607-", - "A157608-", - "A157609-", - "T157610-", - "A157611-", - "T157612-", - "T157613-", - "A157614-", - "C157615-", - "G157616-", - "A157617-", - "A157618-", - "A157619-", - "T157620-", - "A157621-", - "T157622-", - "T157623-", - "T157624-", - "T157625-", - "G157626-", - "A157627-", - "G157628-", - "A157629-", - "C157630-", - "T157631-", - "C157632-", - "A157633-", - "T157634-", - "C157635-", - "A157636-", - "A157637-", - "C157638-", - "A157639-", - "A157640-", - "T157641-", - "G157642-", - "A157643-", - "A157644-", - "A157645-", - "A157646-", - "C157647-", - "T157648-", - "T157649-", - "T157650-", - "A157651-", - "A157652-", - "A157653-", - "T157654-", - "A157655-", - "C157656-", - "T157657-", - "T157658-", - "A157659-", - "A157660-", - "C157661-", - "A157662-", - "G157663-", - "A157664-", - "G157665-", - "G157666-", - "A157667-", - "A157668-", - "T157669-", - "C157670-", - "A157671-", - "A157672-", - "T157673-", - "G157674-", - "A157675-", - "T157676-", - "A157677-", - "A157678-", - "A157679-", - "A157680-", - "A157681-", - "T157682-", - "T157683-", - "T157684-", - "T157685-", - "A157686-", - "A157687-", - "G157688-", - "C157689-", - "G157690-", - "A157691-", - "T157692-", - "G157693-", - "A157694-", - "T157695-", - "A157696-", - "T157697-", - "G157698-", - "T157699-", - "T157700-", - "A157701-", - "T157702-", - "A157703-", - "T157704-", - "A157705-", - "T157706-", - "A157707-", - "A157708-", - "A157709-", - "A157710-", - "A157711-", - "A157712-", - "T157713-", - "G157714-", - "A157715-", - "G157716-", - "G157717-", - "A157718-", - "T157719-", - "T157720-", - "T157721-", - "C157722-", - "A157723-", - "C157724-", - "C157725-", - "C157726-", - "C157727-", - "A157728-", - "C157729-", - "T157730-", - "G157731-", - "A157732-", - "T157733-", - "T157734-", - "C157735-", - "T157736-", - "C157737-", - "A157738-", - "T157739-", - "T157740-", - "A157741-", - "A157742-", - "A157743-", - "T157744-", - "G157745-", - "G157746-", - "T157747-", - "T157748-", - "A157749-", - "G157750-", - "A157751-", - "G157752-", - "A157753-", - "G157754-", - "T157755-", - "A157756-", - "C157757-", - "A157758-", - "C157759-", - "C157760-", - "A157761-", - "A157762-", - "C157763-", - "C157764-", - "A157765-", - "T157766-", - "G157767-", - "T157768-", - "A157769-", - "C157770-", - "C157771-", - "G157772-", - "T157773-", - "C157774-", - "G157775-", - "A157776-", - "G157777-", - "T157778-", - "T157779-", - "A157780-", - "C157781-", - "T157782-", - "T157783-", - "A157784-", - "G157785-", - "A157786-", - "T157787-", - "G157788-", - "C157789-", - "C157790-", - "T157791-", - "C157792-", - "A157793-", - "G157794-", - "A157795-", - "A157796-", - "T157797-", - "A157798-", - "T157799-", - "C157800-", - "A157801-", - "T157802-", - "T157803-", - "T157804-", - "C157805-", - "T157806-", - "T157807-", - "T157808-", - "C157809-", - "C157810-", - "C157811-", - "C157812-", - "A157813-", - "C157814-", - "A157815-", - "A157816-", - "G157817-", - "T157818-", - "T157819-", - "A157820-", - "T157821-", - "A157822-", - "A157823-", - "A157824-", - "A157825-", - "T157826-", - "C157827-", - "A157828-", - "C157829-", - "T157830-", - "T157831-", - "T157832-", - "A157833-", - "T157834-", - "A157835-", - "G157836-", - "T157837-", - "C157838-", - "A157839-", - "T157840-", - "C157841-", - "G157842-", - "A157843-", - "C157844-", - "T157845-", - "G157846-", - "G157847-", - "T157848-", - "T157849-", - "A157850-", - "G157851-", - "T157852-", - "T157853-", - "C157854-", - "A157855-", - "A157856-", - "T157857-", - "C157858-", - "T157859-", - "A157860-", - "C157861-", - "G157862-", - "A157863-", - "A157864-", - "T157865-", - "G157866-", - "T157867-", - "A157868-", - "T157869-", - "A157870-", - "A157871-", - "C157872-", - "A157873-", - "T157874-", - "T157875-", - "C157876-", - "T157877-", - "T157878-", - "A157879-", - "A157880-", - "A157881-", - "C157882-", - "A157883-", - "A157884-", - "T157885-", - "A157886-", - "T157887-", - "A157888-", - "G157889-", - "C157890-", - "A157891-", - "T157892-", - "T157893-", - "C157894-", - "T157895-", - "T157896-", - "G157897-", - "G157898-", - "A157899-", - "T157900-", - "A157901-", - "A157902-", - "A157903-", - "T157904-", - "C157905-", - "A157906-", - "T157907-", - "T157908-", - "T157909-", - "C157910-", - "C157911-", - "T157912-", - "A157913-", - "G157914-", - "A157915-", - "T157916-", - "A157917-", - "C157918-", - "C157919-", - "A157920-", - "T157921-", - "A157922-", - "T157923-", - "C157924-", - "A157925-", - "T157926-", - "C157927-", - "G157928-", - "A157929-", - "G157930-", - "T157931-", - "T157932-", - "G157933-", - "A157934-", - "T157935-", - "A157936-", - "T157937-", - "C157938-", - "T157939-", - "A157940-", - "T157941-", - "C157942-", - "G157943-", - "G157944-", - "T157945-", - "A157946-", - "T157947-", - "A157948-", - "A157949-", - "G157950-", - "T157951-", - "A157952-", - "A157953-", - "T157954-", - "T157955-", - "C157956-", - "A157957-", - "C157958-", - "A157959-", - "T157960-", - "G157961-", - "A157962-", - "T157963-", - "A157964-", - "A157965-", - "G157966-", - "A157967-", - "T157968-", - "T157969-", - "T157970-", - "C157971-", - "C157972-", - "A157973-", - "T157974-", - "A157975-", - "A157976-", - "A157977-", - "C157978-", - "T157979-", - "G157980-", - "C157981-", - "T157982-", - "A157983-", - "C157984-", - "A157985-", - "A157986-", - "T157987-", - "C157988-", - "A157989-", - "T157990-", - "A157991-", - "A157992-", - "A157993-", - "A157994-", - "A157995-", - "A157996-", - "A157997-", - "T157998-", - "T157999-", - "C158000-", - "A158001-", - "T158002-", - "G158003-", - "G158004-", - "G158005-", - "A158006-", - "A158007-", - "A158008-", - "T158009-", - "G158010-", - "A158011-", - "T158012-", - "A158013-", - "T158014-", - "C158015-", - "T158016-", - "T158017-", - "C158018-", - "A158019-", - "C158020-", - "G158021-", - "T158022-", - "A158023-", - "G158024-", - "A158025-", - "T158026-", - "A158027-", - "T158028-", - "A158029-", - "G158030-", - "G158031-", - "T158032-", - "G158033-", - "T158034-", - "A158035-", - "G158036-", - "T158037-", - "T158038-", - "T158039-", - "C158040-", - "G158041-", - "C158042-", - "A158043-", - "G158044-", - "T158045-", - "G158046-", - "A158047-", - "C158048-", - "C158049-", - "G158050-", - "T158051-", - "C158052-", - "C158053-", - "T158054-", - "G158055-", - "G158056-", - "A158057-", - "T158058-", - "A158059-", - "A158060-", - "T158061-", - "A158062-", - "T158063-", - "T158064-", - "A158065-", - "T158066-", - "C158067-", - "T158068-", - "A158069-", - "T158070-", - "A158071-", - "T158072-", - "G158073-", - "A158074-", - "T158075-", - "G158076-", - "G158077-", - "G158078-", - "T158079-", - "G158080-", - "G158081-", - "A158082-", - "T158083-", - "A158084-", - "T158085-", - "G158086-", - "A158087-", - "T158088-", - "C158089-", - "A158090-", - "G158091-", - "T158092-", - "C158093-", - "C158094-", - "C158095-", - "T158096-", - "G158097-", - "T158098-", - "A158099-", - "T158100-", - "A158101-", - "G158102-", - "A158103-", - "A158104-", - "G158105-", - "T158106-", - "T158107-", - "C158108-", - "A158109-", - "A158110-", - "A158111-", - "G158112-", - "G158113-", - "T158114-", - "T158115-", - "A158116-", - "T158117-", - "A158118-", - "G158119-", - "C158120-", - "G158121-", - "T158122-", - "A158123-", - "C158124-", - "A158125-", - "A158126-", - "T158127-", - "A158128-", - "C158129-", - "A158130-", - "T158131-", - "G158132-", - "T158133-", - "A158134-", - "C158135-", - "T158136-", - "A158137-", - "A158138-", - "T158139-", - "T158140-", - "C158141-", - "T158142-", - "T158143-", - "G158144-", - "G158145-", - "A158146-", - "T158147-", - "A158148-", - "T158149-", - "A158150-", - "T158151-", - "G158152-", - "A158153-", - "T158154-", - "A158155-", - "T158156-", - "A158157-", - "C158158-", - "C158159-", - "A158160-", - "G158161-", - "A158162-", - "G158163-", - "C158164-", - "T158165-", - "A158166-", - "A158167-", - "A158168-", - "A158169-", - "A158170-", - "T158171-", - "A158172-", - "T158173-", - "C158174-", - "A158175-", - "T158176-", - "C158177-", - "G158178-", - "T158179-", - "T158180-", - "C158181-", - "T158182-", - "A158183-", - "A158184-", - "T158185-", - "T158186-", - "G158187-", - "C158188-", - "G158189-", - "G158190-", - "A158191-", - "G158192-", - "G158193-", - "A158194-", - "G158195-", - "T158196-", - "T158197-", - "G158198-", - "C158199-", - "C158200-", - "A158201-", - "A158202-", - "T158203-", - "G158204-", - "A158205-", - "C158206-", - "G158207-", - "A158208-", - "A158209-", - "T158210-", - "A158211-", - "C158212-", - "A158213-", - "T158214-", - "T158215-", - "T158216-", - "A158217-", - "T158218-", - "T158219-", - "G158220-", - "T158221-", - "A158222-", - "T158223-", - "A158224-", - "G158225-", - "G158226-", - "C158227-", - "G158228-", - "G158229-", - "T158230-", - "A158231-", - "T158232-", - "A158233-", - "C158234-", - "G158235-", - "C158236-", - "G158237-", - "A158238-", - "T158239-", - "C158240-", - "A158241-", - "G158242-", - "G158243-", - "A158244-", - "G158245-", - "T158246-", - "C158247-", - "A158248-", - "T158249-", - "C158250-", - "G158251-", - "T158252-", - "T158253-", - "G158254-", - "A158255-", - "T158256-", - "A158257-", - "T158258-", - "C158259-", - "T158260-", - "A158261-", - "G158262-", - "T158263-", - "A158264-", - "T158265-", - "C158266-", - "G158267-", - "A158268-", - "T158269-", - "A158270-", - "G158271-", - "A158272-", - "T158273-", - "G158274-", - "G158275-", - "A158276-", - "A158277-", - "G158278-", - "C158279-", - "C158280-", - "A158281-", - "T158282-", - "C158283-", - "A158284-", - "A158285-", - "A158286-", - "A158287-", - "C158288-", - "C158289-", - "A158290-", - "T158291-", - "A158292-", - "T158293-", - "T158294-", - "G158295-", - "G158296-", - "C158297-", - "A158298-", - "G158299-", - "A158300-", - "A158301-", - "G158302-", - "T158303-", - "A158304-", - "T158305-", - "G158306-", - "C158307-", - "T158308-", - "A158309-", - "A158310-", - "A158311-", - "A158312-", - "T158313-", - "G158314-", - "T158315-", - "G158316-", - "C158317-", - "G158318-", - "A158319-", - "A158320-", - "C158321-", - "C158322-", - "A158323-", - "A158324-", - "A158325-", - "A158326-", - "T158327-", - "G158328-", - "T158329-", - "G158330-", - "A158331-", - "T158332-", - "A158333-", - "T158334-", - "G158335-", - "G158336-", - "G158337-", - "G158338-", - "T158339-", - "T158340-", - "G158341-", - "C158342-", - "G158343-", - "A158344-", - "T158345-", - "T158346-", - "T158347-", - "T158348-", - "A158349-", - "A158350-", - "A158351-", - "C158352-", - "G158353-", - "G158354-", - "A158355-", - "T158356-", - "T158357-", - "A158358-", - "A158359-", - "T158360-", - "A158361-", - "T158362-", - "A158363-", - "T158364-", - "G158365-", - "T158366-", - "C158367-", - "A158368-", - "T158369-", - "A158370-", - "G158371-", - "G158372-", - "T158373-", - "G158374-", - "G158375-", - "A158376-", - "G158377-", - "T158378-", - "C158379-", - "G158380-", - "T158381-", - "T158382-", - "A158383-", - "A158384-", - "A158385-", - "G158386-", - "G158387-", - "T158388-", - "G158389-", - "A158390-", - "C158391-", - "A158392-", - "C158393-", - "A158394-", - "C158395-", - "A158396-", - "T158397-", - "A158398-", - "T158399-", - "A158400-", - "C158401-", - "C158402-", - "A158403-", - "A158404-", - "C158405-", - "G158406-", - "C158407-", - "A158408-", - "C158409-", - "T158410-", - "A158411-", - "G158412-", - "A158413-", - "G158414-", - "A158415-", - "G158416-", - "T158417-", - "T158418-", - "T158419-", - "A158420-", - "T158421-", - "C158422-", - "A158423-", - "G158424-", - "A158425-", - "A158426-", - "G158427-", - "A158428-", - "T158429-", - "G158430-", - "G158431-", - "A158432-", - "T158433-", - "G158434-", - "G158435-", - "A158436-", - "T158437-", - "G158438-", - "A158439-", - "A158440-", - "T158441-", - "C158442-", - "A158443-", - "T158444-", - "C158445-", - "A158446-", - "A158447-", - "C158448-", - "G158449-", - "T158450-", - "C158451-", - "T158452-", - "T158453-", - "C158454-", - "C158455-", - "A158456-", - "A158457-", - "T158458-", - "A158459-", - "A158460-", - "A158461-", - "A158462-", - "A158463-", - "T158464-", - "G158465-", - "T158466-", - "C158467-", - "C158468-", - "A158469-", - "A158470-", - "T158471-", - "A158472-", - "T158473-", - "G158474-", - "T158475-", - "C158476-", - "G158477-", - "A158478-", - "C158479-", - "G158480-", - "A158481-", - "T158482-", - "T158483-", - "G158484-", - "T158485-", - "T158486-", - "C158487-", - "A158488-", - "T158489-", - "G158490-", - "C158491-", - "T158492-", - "G158493-", - "G158494-", - "A158495-", - "A158496-", - "A158497-", - "G158498-", - "A158499-", - "T158500-", - "T158501-", - "T158502-", - "A158503-", - "T158504-", - "A158505-", - "T158506-", - "A158507-", - "T158508-", - "C158509-", - "T158510-", - "A158511-", - "G158512-", - "A158513-", - "G158514-", - "G158515-", - "T158516-", - "T158517-", - "A158518-", - "C158519-", - "A158520-", - "A158521-", - "C158522-", - "A158523-", - "A158524-", - "T158525-", - "A158526-", - "G158527-", - "T158528-", - "A158529-", - "G158530-", - "T158531-", - "G158532-", - "T158533-", - "A158534-", - "G158535-", - "T158536-", - "T158537-", - "A158538-", - "A158539-", - "T158540-", - "G158541-", - "T158542-", - "A158543-", - "A158544-", - "T158545-", - "A158546-", - "T158547-", - "C158548-", - "G158549-", - "A158550-", - "A158551-", - "T158552-", - "C158553-", - "T158554-", - "A158555-", - "G158556-", - "T158557-", - "C158558-", - "C158559-", - "T158560-", - "T158561-", - "A158562-", - "G158563-", - "C158564-", - "T158565-", - "A158566-", - "T158567-", - "A158568-", - "A158569-", - "T158570-", - "C158571-", - "C158572-", - "G158573-", - "A158574-", - "T158575-", - "A158576-", - "T158577-", - "A158578-", - "T158579-", - "G158580-", - "A158581-", - "T158582-", - "G158583-", - "A158584-", - "A158585-", - "T158586-", - "G158587-", - "G158588-", - "A158589-", - "C158590-", - "C158591-", - "A158592-", - "A158593-", - "A158594-", - "T158595-", - "T158596-", - "A158597-", - "T158598-", - "C158599-", - "A158600-", - "T158601-", - "C158602-", - "A158603-", - "T158604-", - "T158605-", - "A158606-", - "A158607-", - "A158608-", - "T158609-", - "A158610-", - "T158611-", - "T158612-", - "C158613-", - "C158614-", - "T158615-", - "A158616-", - "G158617-", - "A158618-", - "A158619-", - "T158620-", - "T158621-", - "A158622-", - "A158623-", - "T158624-", - "C158625-", - "C158626-", - "T158627-", - "G158628-", - "C158629-", - "T158630-", - "C158631-", - "T158632-", - "A158633-", - "G160043-", - "A162901-", - "T163190-", - "A163191-", - "A163192-", - "C163193-", - "T163194-", - "A163195-", - "A163196-", - "C163197-", - "T165054-", - "C165055-", - "T166655-", - "T166656-", - "T166711-", - "T168116-", - "T168214-", - "A168956-", - "A169024-", - "T169162-", - "A169581-", - "G169718-", - "A169719-", - "T169720-", - "T169721-", - "C169722-", - "A169723-", - "A169777-", - "G169778-", - "A169779-", - "A169780-", - "G169781-", - "A169782-", - "T169783-", - "A169784-", - "T169785-", - "C169786-", - "A169787-", - "T169788-", - "G169789-", - "A169790-", - "A169791-", - "T169792-", - "G169793-", - "A169794-", - "A169795-", - "A169796-", - "A170723-", - "T170897-", - "T170898-", - "G170914-", - "T172059-", - "T172079-", - "T172080-", - "T172661-", - "G173004-", - "T173005-", - "G173006-", - "A173007-", - "C173008-", - "A173009-", - "T173010-", - "G173011-", - "A173012-", - "T173013-", - "G173014-", - "T173015-", - "C173016-", - "G173017-", - "T173018-", - "T173019-", - "A173020-", - "A173021-", - "A173022-", - "T173023-", - "T173024-", - "T173025-", - "G173026-", - "A173027-", - "C173028-", - "A173029-", - "A173030-", - "T173031-", - "C173032-", - "G173033-", - "T173034-", - "G173035-", - "T173036-", - "C173037-", - "T173038-", - "G173039-", - "T173040-", - "C173041-", - "T173042-", - "C173043-", - "A173044-", - "G173045-", - "A173046-", - "A173047-", - "T173048-", - "C173049-", - "A173050-", - "A173051-", - "A173052-", - "T173053-", - "A173054-", - "T173055-", - "A173056-", - "G173057-", - "A173058-", - "T173059-", - "C173060-", - "T173061-", - "T173062-", - "A173063-", - "T173064-", - "C173065-", - "T173066-", - "C173067-", - "G173068-", - "T173069-", - "A173070-", - "T173071-", - "C173072-", - "C173073-", - "A173074-", - "C173075-", - "A173076-", - "A173077-", - "A173078-", - "T173079-", - "A173080-", - "G173081-", - "T173082-", - "A173083-", - "A173084-", - "A173085-", - "T173086-", - "G173087-", - "A173088-", - "G173089-", - "A173090-", - "G173091-", - "A173092-", - "T173093-", - "C173094-", - "T173095-", - "A173096-", - "C173097-", - "T173098-", - "G173099-", - "G173100-", - "T173101-", - "A173102-", - "A173103-", - "A173104-", - "A173105-", - "T173106-", - "G173107-", - "G173108-", - "T173109-", - "A173110-", - "T173111-", - "G173112-", - "T173113-", - "C173114-", - "C173115-", - "C173116-", - "A173117-", - "A173118-", - "T173119-", - "A173120-", - "T173121-", - "T173122-", - "A173123-", - "A173124-", - "T173125-", - "G173126-", - "C173127-", - "A173128-", - "T173129-", - "T173130-", - "T173131-", - "A173132-", - "T173133-", - "T173134-", - "T173135-", - "C173136-", - "T173137-", - "A173138-", - "G173139-", - "T173140-", - "A173141-", - "A173142-", - "C173143-", - "G173144-", - "T173145-", - "A173146-", - "A173147-", - "A173148-", - "C173149-", - "A173150-", - "C173151-", - "A173152-", - "G173153-", - "A173154-", - "A173155-", - "T173156-", - "T173157-", - "A173158-", - "T173159-", - "A173160-", - "T173161-", - "G173162-", - "G173163-", - "A173164-", - "G173165-", - "C173166-", - "G173167-", - "G173168-", - "A173169-", - "C173170-", - "A173171-", - "T173172-", - "C173173-", - "G173174-", - "A173175-", - "C173176-", - "G173177-", - "C173178-", - "C173179-", - "T173180-", - "T173181-", - "A173182-", - "G173183-", - "A173184-", - "A173185-", - "A173186-", - "T173187-", - "A173188-", - "A173189-", - "G173190-", - "A173191-", - "G173192-", - "A173193-", - "C173194-", - "T173195-", - "T173196-", - "A173197-", - "A173198-", - "A173199-", - "C173200-", - "A173201-", - "A173202-", - "C173203-", - "G173204-", - "G173205-", - "A173206-", - "C173207-", - "A173208-", - "C173209-", - "C173210-", - "T173211-", - "G173212-", - "G173213-", - "A173214-", - "A173215-", - "T173216-", - "T173217-", - "A173218-", - "T173219-", - "T173220-", - "A173221-", - "C173222-", - "C173223-", - "A173224-", - "T173225-", - "A173226-", - "G173227-", - "A173228-", - "A173229-", - "G173230-", - "A173231-", - "T173232-", - "G173233-", - "T173234-", - "T173235-", - "A173236-", - "G173237-", - "A173238-", - "A173239-", - "A173240-", - "A173241-", - "A173242-", - "A173243-", - "T173244-", - "G173245-", - "A173246-", - "T173247-", - "G173248-", - "C173249-", - "T173250-", - "G173251-", - "G173252-", - "T173253-", - "T173254-", - "A173255-", - "T173256-", - "T173257-", - "A173258-", - "T173259-", - "A173260-", - "C173261-", - "A173262-", - "T173263-", - "G173264-", - "T173265-", - "G173266-", - "T173267-", - "T173268-", - "T173269-", - "T173270-", - "A173271-", - "G173272-", - "A173273-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "A173300-", - "T173301-", - "A173302-", - "T173303-", - "A173304-", - "T173305-", - "A173306-", - "T173307-", - "A173308-", - "T173309-", - "A173310-", - "T173311-", - "A173312-", - "T173313-", - "A173314-", - "T173315-", - "A173316-", - "T173317-", - "G173318-", - "G173319-", - "G173320-", - "C173321-", - "A173322-", - "A173323-", - "A173324-", - "A173325-", - "C173326-", - "A173327-", - "T173328-", - "A173329-", - "T173330-", - "A173331-", - "A173332-", - "C173333-", - "G173334-", - "T173335-", - "A173336-", - "A173337-", - "C173338-", - "C173339-", - "A173340-", - "G173341-", - "A173342-", - "A173343-", - "T173344-", - "T173345-", - "A173346-", - "T173347-", - "A173348-", - "A173349-", - "A173350-", - "A173351-", - "T173352-", - "T173353-", - "A173354-", - "G173355-", - "A173356-", - "G173357-", - "G173358-", - "T173359-", - "A173360-", - "C173361-", - "G173362-", - "G173363-", - "G173364-", - "A173365-", - "T173366-", - "A173367-", - "G173368-", - "A173369-", - "A173370-", - "T173371-", - "A173372-", - "A173373-", - "T173374-", - "A173375-", - "C173376-", - "C173377-", - "T173378-", - "C173379-", - "C173380-", - "T173381-", - "A173382-", - "C173383-", - "T173384-", - "A173385-", - "T173386-", - "G173387-", - "A173388-", - "A173389-", - "A173390-", - "T173391-", - "T173392-", - "A173393-", - "C173394-", - "C173395-", - "A173396-", - "G173397-", - "A173398-", - "A173399-", - "G173400-", - "G173401-", - "A173402-", - "G173403-", - "T173404-", - "A173405-", - "G173406-", - "T173407-", - "A173408-", - "A173409-", - "C173410-", - "T173411-", - "T173412-", - "C173413-", - "A173414-", - "A173415-", - "T173416-", - "A173417-", - "G173418-", - "G173419-", - "T173420-", - "A173421-", - "G173422-", - "T173423-", - "A173424-", - "A173425-", - "T173426-", - "T173427-", - "T173428-", - "G173429-", - "A173430-", - "C173431-", - "T173432-", - "A173433-", - "T173434-", - "T173435-", - "G173436-", - "C173437-", - "A173438-", - "T173439-", - "G173440-", - "T173441-", - "A173442-", - "G173443-", - "A173444-", - "G173445-", - "T173446-", - "A173447-", - "T173448-", - "C173449-", - "G173450-", - "T173451-", - "T173452-", - "G173453-", - "A173454-", - "G173455-", - "A173456-", - "C173457-", - "T173458-", - "T173459-", - "C173460-", - "C173461-", - "C173462-", - "A173463-", - "C173464-", - "A173465-", - "A173466-", - "C173467-", - "G173468-", - "G173469-", - "A173470-", - "C173471-", - "A173472-", - "C173473-", - "C173474-", - "G173475-", - "A173476-", - "C173477-", - "G173478-", - "T173479-", - "C173480-", - "T173481-", - "T173482-", - "T173483-", - "T173484-", - "G173485-", - "G173486-", - "A173487-", - "T173488-", - "A173489-", - "A173490-", - "G173491-", - "T173492-", - "A173493-", - "A173494-", - "T173495-", - "G173496-", - "G173497-", - "T173498-", - "A173499-", - "T173500-", - "A173501-", - "T173502-", - "G173503-", - "T173504-", - "A173505-", - "T173506-", - "T173507-", - "A173508-", - "C173509-", - "G173510-", - "A173511-", - "A173512-", - "G173513-", - "A173514-", - "A173515-", - "G173516-", - "A173517-", - "A173518-", - "G173519-", - "A173520-", - "C173521-", - "G173522-", - "A173523-", - "G173524-", - "G173525-", - "A173526-", - "C173527-", - "G173528-", - "G173529-", - "A173530-", - "G173531-", - "A173532-", - "C173533-", - "G173534-", - "G173535-", - "T173536-", - "A173537-", - "G173538-", - "A173539-", - "A173540-", - "T173541-", - "A173542-", - "A173543-", - "G173544-", - "T173545-", - "G173546-", - "T173547-", - "A173548-", - "G173549-", - "C173550-", - "A173551-", - "A173552-", - "A173553-", - "T173554-", - "A173555-", - "A173556-", - "A173557-", - "A173558-", - "T173559-", - "C173560-", - "T173561-", - "A173562-", - "T173563-", - "A173564-", - "T173565-", - "G173566-", - "A173567-", - "C173568-", - "C173569-", - "G173570-", - "A173571-", - "T173572-", - "A173573-", - "A173574-", - "G173575-", - "A173576-", - "G173577-", - "A173578-", - "C173579-", - "G173580-", - "T173581-", - "G173582-", - "T173583-", - "T173584-", - "A173585-", - "T173586-", - "T173587-", - "A173588-", - "C173589-", - "A173590-", - "T173591-", - "C173592-", - "C173593-", - "T173594-", - "G173595-", - "G173596-", - "T173597-", - "T173598-", - "A173599-", - "A173600-", - "A173601-", - "C173602-", - "A173603-", - "T173604-", - "T173605-", - "A173606-", - "A173607-", - "T173608-", - "C173609-", - "C173610-", - "T173611-", - "G173612-", - "T173613-", - "C173614-", - "A173615-", - "A173616-", - "G173617-", - "G173618-", - "A173619-", - "A173620-", - "G173621-", - "A173622-", - "A173623-", - "G173624-", - "A173625-", - "T173626-", - "G173627-", - "C173628-", - "T173629-", - "A173630-", - "C173631-", - "A173632-", - "A173633-", - "C173634-", - "G173635-", - "T173636-", - "T173637-", - "T173638-", - "A173639-", - "C173640-", - "G173641-", - "T173642-", - "G173643-", - "T173644-", - "A173645-", - "T173646-", - "G173647-", - "G173648-", - "C173649-", - "G173650-", - "T173651-", - "T173652-", - "T173653-", - "A173654-", - "C173655-", - "T173656-", - "A173657-", - "T173658-", - "T173659-", - "C173660-", - "C173661-", - "T173662-", - "A173663-", - "G173664-", - "C173665-", - "A173666-", - "T173667-", - "C173668-", - "A173669-", - "G173670-", - "C173671-", - "A173672-", - "A173673-", - "A173674-", - "A173675-", - "C173676-", - "A173677-", - "G173678-", - "T173679-", - "T173680-", - "A173681-", - "C173682-", - "T173683-", - "G173684-", - "T173685-", - "T173686-", - "A173687-", - "G173688-", - "T173689-", - "A173690-", - "A173691-", - "A173692-", - "C173693-", - "G173694-", - "T173695-", - "G173696-", - "A173697-", - "A173698-", - "T173699-", - "G173700-", - "T173701-", - "A173702-", - "T173703-", - "G173704-", - "T173705-", - "T173706-", - "G173707-", - "T173708-", - "T173709-", - "A173710-", - "C173711-", - "A173712-", - "T173713-", - "T173714-", - "T173715-", - "C173716-", - "C173717-", - "A173718-", - "T173719-", - "A173720-", - "T173721-", - "C173722-", - "A173723-", - "A173724-", - "T173725-", - "T173726-", - "G173727-", - "A173728-", - "G173729-", - "T173730-", - "T173731-", - "T173732-", - "A173733-", - "T173734-", - "A173735-", - "A173736-", - "G173737-", - "A173738-", - "A173739-", - "T173740-", - "T173741-", - "T173742-", - "T173743-", - "T173744-", - "T173745-", - "A173746-", - "T173747-", - "A173748-", - "C173749-", - "A173750-", - "T173751-", - "T173752-", - "A173753-", - "T173754-", - "C173755-", - "T173756-", - "T173757-", - "C173758-", - "C173759-", - "A173760-", - "A173761-", - "C173762-", - "A173763-", - "A173764-", - "A173765-", - "C173766-", - "A173767-", - "A173768-", - "T173769-", - "T173770-", - "G173771-", - "A173772-", - "C173773-", - "G173774-", - "A173775-", - "A173776-", - "C173777-", - "G173778-", - "T173779-", - "A173780-", - "T173781-", - "T173782-", - "G173783-", - "C173784-", - "T173785-", - "A173786-", - "T173787-", - "G173788-", - "A173789-", - "T173790-", - "T173791-", - "A173792-", - "A173793-", - "C173794-", - "T173795-", - "C173796-", - "C173797-", - "C173798-", - "A173799-", - "C173800-", - "A173801-", - "A173802-", - "T173803-", - "A173804-", - "C173805-", - "T173806-", - "A173807-", - "T173808-", - "A173809-", - "T173810-", - "A173811-", - "T173812-", - "A173813-", - "T173814-", - "T173815-", - "A173816-", - "T173817-", - "T173818-", - "A173819-", - "A173820-", - "T173821-", - "C173822-", - "A173823-", - "T173824-", - "T173825-", - "A173826-", - "A173827-", - "C173828-", - "T173829-", - "T173830-", - "G173831-", - "C173832-", - "A173833-", - "G173834-", - "A173835-", - "C173836-", - "T173837-", - "A173838-", - "T173839-", - "A173840-", - "C173841-", - "C173842-", - "T173843-", - "A173844-", - "G173845-", - "T173846-", - "A173847-", - "G173848-", - "T173849-", - "G173850-", - "C173851-", - "T173852-", - "A173853-", - "T173854-", - "T173855-", - "T173856-", - "T173857-", - "G173858-", - "A173859-", - "C173860-", - "A173861-", - "T173862-", - "A173863-", - "C173864-", - "T173865-", - "C173866-", - "A173867-", - "T173868-", - "G173869-", - "T173870-", - "T173871-", - "C173872-", - "T173873-", - "T173874-", - "G173875-", - "T173876-", - "G173877-", - "T173878-", - "A173879-", - "A173880-", - "T173881-", - "C173882-", - "G173883-", - "C173884-", - "A173885-", - "G173886-", - "T173887-", - "A173888-", - "T173889-", - "C173890-", - "T173891-", - "A173892-", - "T173893-", - "A173894-", - "T173895-", - "T173896-", - "A173897-", - "T173898-", - "T173899-", - "A173900-", - "A173901-", - "A173902-", - "G173903-", - "T173904-", - "A173905-", - "C173906-", - "G173907-", - "T173908-", - "A173909-", - "A173910-", - "A173911-", - "T173912-", - "C173913-", - "T173914-", - "A173915-", - "G173916-", - "C173917-", - "T173918-", - "A173919-", - "T173920-", - "A173921-", - "G173922-", - "T173923-", - "T173924-", - "T173925-", - "T173926-", - "A173927-", - "T173928-", - "T173929-", - "A173930-", - "T173931-", - "T173932-", - "T173933-", - "A173934-", - "A173935-", - "T173936-", - "T173937-", - "T173938-", - "T173939-", - "A173940-", - "G173941-", - "A173942-", - "T173943-", - "A173944-", - "A173945-", - "T173946-", - "A173947-", - "T173948-", - "A173949-", - "C173950-", - "T173951-", - "G173952-", - "T173953-", - "C173954-", - "T173955-", - "C173956-", - "C173957-", - "G173958-", - "T173959-", - "A173960-", - "T173961-", - "T173962-", - "T173963-", - "T173964-", - "T173965-", - "A173966-", - "A173967-", - "A173968-", - "A173969-", - "A173970-", - "A173971-", - "T173972-", - "T173973-", - "A173974-", - "C173975-", - "C173976-", - "A173977-", - "C173978-", - "A173979-", - "T173980-", - "C173981-", - "C173982-", - "T173983-", - "T173984-", - "T173985-", - "A173986-", - "T173987-", - "T173988-", - "A173989-", - "A173990-", - "A173991-", - "T173992-", - "C173993-", - "A173994-", - "T173995-", - "G173996-", - "A173997-", - "A173998-", - "T173999-", - "G174000-", - "G174001-", - "G174002-", - "A174003-", - "A174004-", - "T174005-", - "T174006-", - "T174007-", - "C174008-", - "T174009-", - "G174010-", - "T174011-", - "G174012-", - "T174013-", - "C174014-", - "A174015-", - "T174016-", - "C174017-", - "G174018-", - "T174019-", - "T174020-", - "A174021-", - "G174022-", - "T174023-", - "A174024-", - "T174025-", - "A174026-", - "T174027-", - "T174028-", - "G174029-", - "T174030-", - "G174031-", - "A174032-", - "A174033-", - "C174034-", - "A174035-", - "A174036-", - "C174037-", - "A174038-", - "A174039-", - "G174040-", - "A174041-", - "G174042-", - "C174043-", - "A174044-", - "G174045-", - "A174046-", - "T174047-", - "A174048-", - "T174049-", - "C174050-", - "T174051-", - "A174052-", - "T174053-", - "A174054-", - "G174055-", - "G174056-", - "A174057-", - "A174058-", - "A174059-", - "G174060-", - "G174061-", - "G174062-", - "T174063-", - "G174064-", - "G174065-", - "A174066-", - "A174067-", - "T174068-", - "G174069-", - "C174070-", - "G174071-", - "A174072-", - "T174073-", - "A174074-", - "C174075-", - "A174076-", - "T174077-", - "T174078-", - "G174079-", - "A174080-", - "T174081-", - "C174082-", - "T174083-", - "A174084-", - "T174085-", - "G174086-", - "T174087-", - "A174088-", - "G174089-", - "T174090-", - "T174091-", - "T174092-", - "T174093-", - "A174094-", - "A174095-", - "A174096-", - "A174097-", - "C174098-", - "A174099-", - "T174100-", - "A174101-", - "C174102-", - "G174103-", - "C174104-", - "G174105-", - "A174106-", - "A174107-", - "C174108-", - "T174109-", - "T174110-", - "T174111-", - "G174112-", - "A174113-", - "A174114-", - "G174115-", - "A174116-", - "A174117-", - "T174118-", - "T174119-", - "T174120-", - "A174121-", - "T174122-", - "A174123-", - "T174124-", - "A174125-", - "A174126-", - "A174127-", - "T174128-", - "C174129-", - "A174130-", - "T174131-", - "C174132-", - "T174133-", - "C174134-", - "A174135-", - "C174136-", - "G174137-", - "A174138-", - "G174139-", - "A174140-", - "T174141-", - "A174142-", - "T174143-", - "T174144-", - "G174145-", - "C174146-", - "T174147-", - "C174148-", - "T174149-", - "C174150-", - "T174151-", - "G174152-", - "T174153-", - "C174154-", - "A174155-", - "T174156-", - "A174157-", - "T174158-", - "T174159-", - "C174160-", - "A174161-", - "T174162-", - "A174163-", - "C174164-", - "A174165-", - "C174166-", - "C174167-", - "T174168-", - "G174169-", - "T174170-", - "A174171-", - "T174172-", - "A174173-", - "A174174-", - "A174175-", - "C174176-", - "T174177-", - "T174178-", - "T174179-", - "C174180-", - "T174181-", - "A174182-", - "G174183-", - "A174184-", - "C174185-", - "A174186-", - "T174187-", - "C174188-", - "T174189-", - "T174190-", - "A174191-", - "C174192-", - "A174193-", - "A174194-", - "T174195-", - "G174196-", - "T174197-", - "G174198-", - "T174199-", - "T174200-", - "A174201-", - "T174202-", - "T174203-", - "T174204-", - "T174205-", - "A174206-", - "T174207-", - "G174208-", - "A174209-", - "T174210-", - "C174211-", - "A174212-", - "T174213-", - "A174214-", - "T174215-", - "T174216-", - "T174217-", - "A174218-", - "C174219-", - "A174220-", - "T174221-", - "A174222-", - "T174223-", - "T174224-", - "T174225-", - "A174226-", - "C174227-", - "T174228-", - "G174229-", - "G174230-", - "T174231-", - "A174232-", - "T174233-", - "A174234-", - "T174235-", - "C174236-", - "A174237-", - "A174238-", - "A174239-", - "G174240-", - "A174241-", - "T174242-", - "G174243-", - "T174244-", - "T174245-", - "A174246-", - "G174247-", - "A174248-", - "T174249-", - "T174250-", - "A174251-", - "G174252-", - "T174253-", - "T174254-", - "A174255-", - "A174256-", - "T174257-", - "G174258-", - "G174259-", - "G174260-", - "A174261-", - "A174262-", - "T174263-", - "C174264-", - "G174265-", - "T174266-", - "C174267-", - "T174268-", - "A174269-", - "T174270-", - "A174271-", - "A174272-", - "T174273-", - "A174274-", - "A174275-", - "T174276-", - "G174277-", - "A174278-", - "A174279-", - "T174280-", - "A174281-", - "T174282-", - "T174283-", - "A174284-", - "A174285-", - "A174286-", - "C174287-", - "A174288-", - "A174289-", - "T174290-", - "T174291-", - "A174292-", - "T174293-", - "A174294-", - "G174295-", - "G174296-", - "A174297-", - "G174298-", - "G174299-", - "A174300-", - "G174301-", - "T174302-", - "T174303-", - "T174304-", - "A174305-", - "T174306-", - "A174307-", - "C174308-", - "C174309-", - "T174310-", - "A174311-", - "C174312-", - "A174313-", - "A174314-", - "A174315-", - "A174316-", - "A174317-", - "C174318-", - "A174319-", - "T174320-", - "C174321-", - "A174322-", - "T174323-", - "A174324-", - "A174325-", - "A174326-", - "A174327-", - "A174328-", - "T174329-", - "G174330-", - "A174331-", - "G174332-", - "T174333-", - "C174334-", - "A174335-", - "T174336-", - "C174337-", - "G174338-", - "T174339-", - "C174340-", - "C174341-", - "G174342-", - "A174343-", - "T174344-", - "T174345-", - "T174346-", - "A174347-", - "T174348-", - "G174349-", - "T174350-", - "T174351-", - "T174352-", - "T174353-", - "A174354-", - "A174355-", - "A174356-", - "T174357-", - "A174358-", - "T174359-", - "A174360-", - "C174361-", - "T174362-", - "A174363-", - "A174364-", - "C174365-", - "A174366-", - "T174367-", - "T174368-", - "A174369-", - "C174370-", - "T174371-", - "A174372-", - "C174373-", - "C174374-", - "T174375-", - "T174376-", - "C174377-", - "A174378-", - "G174379-", - "A174380-", - "A174381-", - "A174382-", - "T174383-", - "T174384-", - "A174385-", - "T174386-", - "A174387-", - "T174388-", - "A174389-", - "C174390-", - "G174391-", - "A174392-", - "A174393-", - "A174394-", - "T174395-", - "A174396-", - "T174397-", - "T174398-", - "A174399-", - "T174400-", - "A174401-", - "C174402-", - "A174403-", - "T174404-", - "G174405-", - "C174406-", - "T174407-", - "G174408-", - "A174409-", - "C174410-", - "A174411-", - "A174412-", - "T174413-", - "T174414-", - "A174415-", - "A174416-", - "C174417-", - "G174418-", - "A174419-", - "T174420-", - "C174421-", - "T174422-", - "T174423-", - "T174424-", - "A174425-", - "T174426-", - "A174427-", - "A174428-", - "T174429-", - "A174430-", - "T174431-", - "A174432-", - "T174433-", - "A174434-", - "G174435-", - "T174436-", - "A174437-", - "T174438-", - "C174439-", - "C174440-", - "A174441-", - "C174442-", - "C174443-", - "T174444-", - "A174445-", - "C174446-", - "C174447-", - "A174448-", - "A174449-", - "A174450-", - "G174451-", - "T174452-", - "A174453-", - "T174454-", - "A174455-", - "A174456-", - "T174457-", - "T174458-", - "G174459-", - "T174460-", - "A174461-", - "T174462-", - "T174463-", - "T174464-", - "T174465-", - "T174466-", - "C174467-", - "T174468-", - "C174469-", - "A174470-", - "T174471-", - "G174472-", - "T174473-", - "G174474-", - "A174475-", - "T174476-", - "G174477-", - "T174478-", - "G174479-", - "T174480-", - "G174481-", - "T174482-", - "A174483-", - "A174484-", - "A174485-", - "A174486-", - "A174487-", - "A174488-", - "C174489-", - "T174490-", - "G174491-", - "A174492-", - "T174493-", - "A174494-", - "T174495-", - "T174496-", - "A174497-", - "T174498-", - "A174499-", - "T174500-", - "A174501-", - "A174502-", - "T174503-", - "T174504-", - "A174505-", - "T174506-", - "C174507-", - "T174508-", - "T174509-", - "A174510-", - "G174511-", - "T174512-", - "A174513-", - "C174514-", - "C174515-", - "T174516-", - "A174517-", - "T174518-", - "G174519-", - "A174520-", - "T174521-", - "G174522-", - "A174523-", - "A174524-", - "G174525-", - "A174526-", - "T174527-", - "G174528-", - "A174529-", - "A174530-", - "G174531-", - "A174532-", - "T174533-", - "G174534-", - "A174535-", - "A174536-", - "G174537-", - "A174538-", - "T174539-", - "G174540-", - "A174541-", - "A174542-", - "G174543-", - "A174544-", - "T174545-", - "G174546-", - "A174547-", - "T174548-", - "G174549-", - "G174550-", - "T174551-", - "C174552-", - "C174553-", - "G174554-", - "T174555-", - "A174556-", - "T174557-", - "A174558-", - "T174559-", - "A174560-", - "T174561-", - "T174562-", - "T174563-", - "T174564-", - "G174565-", - "T174566-", - "A174567-", - "T174568-", - "C174569-", - "A174570-", - "T174571-", - "T174572-", - "A174573-", - "T174574-", - "C174575-", - "G174576-", - "T174577-", - "T174578-", - "A174579-", - "T174580-", - "T174581-", - "G174582-", - "C174583-", - "T174584-", - "A174585-", - "T174586-", - "T174587-", - "C174588-", - "C174589-", - "A174590-", - "T174591-", - "A174592-", - "G174593-", - "T174594-", - "T174595-", - "A174596-", - "C174597-", - "G174598-", - "C174599-", - "C174600-", - "A174601-", - "T174602-", - "A174603-", - "G174604-", - "A174605-", - "C174606-", - "A174607-", - "T174608-", - "C174609-", - "G174610-", - "A174611-", - "A174612-", - "A174613-", - "A174614-", - "T174615-", - "G174616-", - "A174617-", - "A174618-", - "A174619-", - "T174620-", - "C174621-", - "A174622-", - "C174623-", - "C174624-", - "G174625-", - "A174626-", - "A174627-", - "T174628-", - "T174629-", - "C174630-", - "T174631-", - "T174632-", - "C174633-", - "A174634-", - "A174635-", - "T174636-", - "A174637-", - "A174638-", - "A174639-", - "A174640-", - "T174641-", - "G174642-", - "A174643-", - "G174644-", - "A174645-", - "G174646-", - "A174647-", - "T174648-", - "A174649-", - "C174650-", - "T174651-", - "C174652-", - "T174653-", - "A174654-", - "C174655-", - "C174656-", - "A174657-", - "G174658-", - "C174659-", - "T174660-", - "A174661-", - "A174662-", - "A174663-", - "G174664-", - "A174665-", - "C174666-", - "T174667-", - "C174668-", - "T174669-", - "A174670-", - "A174671-", - "A174672-", - "T174673-", - "G174674-", - "G174675-", - "T174676-", - "T174677-", - "G174678-", - "A174679-", - "A174680-", - "T174681-", - "C174682-", - "C174683-", - "A174684-", - "G174685-", - "T174686-", - "A174687-", - "T174688-", - "G174689-", - "T174690-", - "A174691-", - "T174692-", - "G174693-", - "T174694-", - "T174695-", - "T174696-", - "G174697-", - "G174698-", - "A174699-", - "G174700-", - "G174701-", - "C174702-", - "A174703-", - "C174704-", - "A174705-", - "A174706-", - "T174707-", - "G174708-", - "A174709-", - "A174710-", - "T174711-", - "G174712-", - "A174713-", - "T174714-", - "A174715-", - "T174716-", - "G174717-", - "G174718-", - "C174719-", - "C174720-", - "G174721-", - "C174722-", - "T174723-", - "C174724-", - "T174725-", - "A174726-", - "G174727-", - "G174728-", - "A174729-", - "G174730-", - "A174731-", - "G174732-", - "C174733-", - "C174734-", - "A174735-", - "T174736-", - "T174737-", - "C174738-", - "A174739-", - "G174740-", - "T174741-", - "G174742-", - "C174743-", - "A174744-", - "A174745-", - "A174746-", - "G174747-", - "T174748-", - "G174749-", - "T174750-", - "C174751-", - "C174752-", - "T174753-", - "C174754-", - "C174755-", - "T174756-", - "A174757-", - "T174758-", - "T174759-", - "G174760-", - "A174761-", - "A174762-", - "G174763-", - "A174764-", - "C174765-", - "A174766-", - "G174767-", - "T174768-", - "C174769-", - "T174770-", - "T174771-", - "T174772-", - "T174773-", - "A174774-", - "T174775-", - "C174776-", - "G174777-", - "C174778-", - "A174779-", - "T174780-", - "A174781-", - "G174782-", - "A174783-", - "T174784-", - "A174785-", - "T174786-", - "A174787-", - "A174788-", - "A174789-", - "G174790-", - "A174791-", - "C174792-", - "T174793-", - "A174794-", - "T174795-", - "G174796-", - "T174797-", - "G174798-", - "G174799-", - "T174800-", - "T174801-", - "A174802-", - "A174803-", - "A174804-", - "T174805-", - "G174806-", - "G174807-", - "G174808-", - "A174809-", - "A174810-", - "A174811-", - "G174812-", - "G174813-", - "C174814-", - "T174815-", - "A174816-", - "G174817-", - "A174818-", - "A174819-", - "A174820-", - "A174821-", - "G174822-", - "A174823-", - "A174824-", - "T174825-", - "A174826-", - "G174827-", - "A174828-", - "C174829-", - "G174830-", - "G174831-", - "C174832-", - "G174833-", - "A174834-", - "C174835-", - "A174836-", - "G174837-", - "G174838-", - "T174839-", - "T174840-", - "T174841-", - "C174842-", - "T174843-", - "A174844-", - "A174845-", - "T174846-", - "A174847-", - "A174848-", - "A174849-", - "C174850-", - "G174851-", - "T174852-", - "G174853-", - "T174854-", - "T174855-", - "A174856-", - "A174857-", - "A174858-", - "C174859-", - "A174860-", - "T174861-", - "G174862-", - "G174863-", - "T174864-", - "G174865-", - "A174866-", - "T174867-", - "T174868-", - "T174869-", - "A174870-", - "T174871-", - "G174872-", - "G174873-", - "A174874-", - "T174875-", - "A174876-", - "G174877-", - "C174878-", - "C174879-", - "A174880-", - "A174881-", - "C174882-", - "T174883-", - "A174884-", - "T174885-", - "A174886-", - "C174887-", - "A174888-", - "T174889-", - "C174890-", - "T174891-", - "A174892-", - "A174893-", - "A174894-", - "T174895-", - "T174896-", - "C174897-", - "A174898-", - "G174899-", - "T174900-", - "A174901-", - "A174902-", - "C174903-", - "C174904-", - "G174905-", - "T174906-", - "A174907-", - "G174908-", - "G174909-", - "T174910-", - "A174911-", - "T174912-", - "T174913-", - "T174914-", - "A174915-", - "T174916-", - "G174917-", - "T174918-", - "A174919-", - "C174920-", - "C174921-", - "G174922-", - "T174923-", - "A174924-", - "A174925-", - "C174926-", - "C174927-", - "A174928-", - "C174929-", - "A174930-", - "A174931-", - "A174932-", - "G174933-", - "A174934-", - "A174935-", - "T174936-", - "G174937-", - "G174938-", - "T174939-", - "G174940-", - "A174941-", - "C174942-", - "T174943-", - "G174944-", - "T174945-", - "G174946-", - "T174947-", - "T174948-", - "C174949-", - "A174950-", - "G174951-", - "G174952-", - "G174953-", - "T174954-", - "G174955-", - "T174956-", - "A174957-", - "G174958-", - "T174959-", - "T174960-", - "A174961-", - "G174962-", - "A174963-", - "T174964-", - "C174965-", - "T174966-", - "C174967-", - "A174968-", - "T174969-", - "G174970-", - "T174971-", - "G174972-", - "T174973-", - "G174974-", - "G174975-", - "A174976-", - "A174977-", - "A174978-", - "C174979-", - "C174980-", - "T174981-", - "T174982-", - "C174983-", - "T174984-", - "T174985-", - "C174986-", - "A174987-", - "T174988-", - "G174989-", - "C174990-", - "A174991-", - "T174992-", - "T174993-", - "C174994-", - "C174995-", - "A174996-", - "A174997-", - "A174998-", - "A174999-", - "A175000-", - "C175001-", - "A175002-", - "T175003-", - "A175004-", - "T175005-", - "G175006-", - "A175007-", - "A175008-", - "C175009-", - "T175010-", - "A175011-", - "G175012-", - "G175013-", - "T175014-", - "A175015-", - "C175016-", - "T175017-", - "T175018-", - "A175019-", - "T175020-", - "G175021-", - "A175022-", - "T175023-", - "A175024-", - "A175025-", - "G175026-", - "T175027-", - "A175028-", - "T175029-", - "G175030-", - "G175031-", - "C175032-", - "A175033-", - "T175034-", - "A175035-", - "G175036-", - "A175037-", - "C175038-", - "T175039-", - "T175040-", - "A175041-", - "T175042-", - "A175043-", - "C175044-", - "T175045-", - "G175046-", - "T175047-", - "G175048-", - "G175049-", - "A175050-", - "A175051-", - "T175052-", - "T175053-", - "C175054-", - "T175055-", - "T175056-", - "T175057-", - "A175058-", - "T175059-", - "G175060-", - "C175061-", - "G175062-", - "A175063-", - "A175064-", - "C175065-", - "C175066-", - "A175067-", - "T175068-", - "T175069-", - "A175070-", - "T175071-", - "A175072-", - "A175073-", - "T175074-", - "A175075-", - "A175076-", - "T175077-", - "A175078-", - "T175079-", - "A175080-", - "A175081-", - "C175082-", - "T175083-", - "T175084-", - "G175085-", - "G175086-", - "T175087-", - "A175088-", - "T175089-", - "A175090-", - "A175091-", - "A175092-", - "G175093-", - "A175094-", - "T175095-", - "A175096-", - "A175097-", - "T175098-", - "A175099-", - "A175100-", - "G175101-", - "G175102-", - "A175103-", - "A175104-", - "A175105-", - "T175106-", - "T175107-", - "A175108-", - "A175109-", - "T175110-", - "A175111-", - "T175112-", - "C175113-", - "G175114-", - "A175115-", - "C175116-", - "G175117-", - "A175118-", - "T175119-", - "T175120-", - "T175121-", - "T175122-", - "A175123-", - "A175124-", - "G175125-", - "T175126-", - "A175127-", - "T175128-", - "T175129-", - "C175130-", - "A175131-", - "C175132-", - "A175133-", - "A175134-", - "G175135-", - "C175136-", - "G175137-", - "G175138-", - "G175139-", - "A175140-", - "A175141-", - "A175142-", - "G175143-", - "G175144-", - "A175145-", - "A175146-", - "T175147-", - "T175148-", - "A175149-", - "A175150-", - "T175151-", - "T175152-", - "A175153-", - "T175154-", - "T175155-", - "C175156-", - "A175157-", - "T175158-", - "A175159-", - "A175160-", - "T175161-", - "C175162-", - "C175163-", - "A175164-", - "G175165-", - "A175166-", - "G175167-", - "T175168-", - "T175169-", - "A175170-", - "G175171-", - "A175172-", - "A175173-", - "G175174-", - "A175175-", - "T175176-", - "A175177-", - "G175178-", - "T175179-", - "G175180-", - "G175181-", - "A175182-", - "A175183-", - "G175184-", - "A175185-", - "T175186-", - "A175187-", - "C175188-", - "G175189-", - "A175190-", - "C175191-", - "T175192-", - "G175193-", - "T175194-", - "T175195-", - "A175196-", - "C175197-", - "G175198-", - "T175199-", - "T175200-", - "C175201-", - "A175202-", - "T175203-", - "T175204-", - "A175205-", - "C175206-", - "G175207-", - "A175208-", - "C175209-", - "G175210-", - "A175211-", - "C175212-", - "G175213-", - "T175214-", - "T175215-", - "A175216-", - "G175217-", - "A175218-", - "A175219-", - "T175220-", - "C175221-", - "A175222-", - "A175223-", - "G175224-", - "A175225-", - "A175226-", - "T175227-", - "G175228-", - "A175229-", - "T175230-", - "A175231-", - "T175232-", - "C175233-", - "G175234-", - "T175235-", - "A175236-", - "G175237-", - "T175238-", - "A175239-", - "T175240-", - "C175241-", - "A175242-", - "A175243-", - "G175244-", - "A175245-", - "T175246-", - "G175247-", - "T175248-", - "A175249-", - "A175250-", - "A175251-", - "A175252-", - "T175253-", - "A175254-", - "C175255-", - "T175256-", - "T175257-", - "A175258-", - "C175259-", - "G175260-", - "G175261-", - "T175262-", - "T175263-", - "A175264-", - "T175265-", - "A175266-", - "C175267-", - "C175268-", - "G175269-", - "T175270-", - "C175271-", - "A175272-", - "C175273-", - "A175274-", - "A175275-", - "G175276-", - "A175277-", - "C175278-", - "C175279-", - "A175280-", - "C175281-", - "A175282-", - "G175283-", - "G175284-", - "T175285-", - "T175286-", - "T175287-", - "A175288-", - "A175289-", - "A175290-", - "C175291-", - "T175292-", - "A175293-", - "A175294-", - "T175295-", - "A175296-", - "C175297-", - "T175298-", - "A175299-", - "G175300-", - "A175301-", - "T175302-", - "C175303-", - "C175304-", - "G175305-", - "A175306-", - "A175307-", - "A175308-", - "A175309-", - "T175310-", - "C175311-", - "A175312-", - "A175313-", - "C175314-", - "G175315-", - "T175316-", - "A175317-", - "A175318-", - "C175319-", - "G175320-", - "A175321-", - "T175322-", - "A175323-", - "G175324-", - "G175325-", - "A175326-", - "G175327-", - "A175328-", - "A175329-", - "C175330-", - "C175331-", - "T175332-", - "G175333-", - "C175334-", - "C175335-", - "A175336-", - "A175337-", - "T175338-", - "A175339-", - "T175340-", - "A175341-", - "A175342-", - "C175343-", - "A175344-", - "T175345-", - "G175346-", - "C175347-", - "A175348-", - "G175349-", - "T175350-", - "G175351-", - "C175352-", - "T175353-", - "G175354-", - "T175355-", - "G175356-", - "T175357-", - "C175358-", - "A175359-", - "A175360-", - "C175361-", - "G175362-", - "T175363-", - "C175364-", - "A175365-", - "T175366-", - "T175367-", - "A175368-", - "T175369-", - "T175370-", - "T175371-", - "G175372-", - "T175373-", - "C175374-", - "G175375-", - "A175376-", - "C175377-", - "G175378-", - "A175379-", - "T175380-", - "G175381-", - "T175382-", - "A175383-", - "C175384-", - "T175385-", - "G175386-", - "A175387-", - "T175388-", - "T175389-", - "G175390-", - "A175391-", - "A175392-", - "T175393-", - "G175394-", - "G175395-", - "G175396-", - "A175397-", - "A175398-", - "A175399-", - "A175400-", - "T175401-", - "C175402-", - "C175403-", - "A175404-", - "T175405-", - "C175406-", - "C175407-", - "G175408-", - "G175409-", - "A175410-", - "T175411-", - "G175412-", - "G175413-", - "A175414-", - "T175415-", - "T175416-", - "A175417-", - "T175418-", - "A175419-", - "G175420-", - "G175421-", - "A175422-", - "T175423-", - "T175424-", - "A175425-", - "G175426-", - "A175427-", - "T175428-", - "T175429-", - "T175430-", - "T175431-", - "G175432-", - "G175433-", - "T175434-", - "G175435-", - "T175436-", - "A175437-", - "T175438-", - "A175439-", - "C175440-", - "T175441-", - "C175442-", - "T175443-", - "A175444-", - "T175445-", - "T175446-", - "T175447-", - "T175448-", - "A175449-", - "A175450-", - "C175451-", - "T175452-", - "A175453-", - "G175454-", - "T175455-", - "A175456-", - "G175457-", - "A175458-", - "G175459-", - "G175460-", - "C175461-", - "G175462-", - "G175463-", - "T175464-", - "A175465-", - "T175466-", - "C175467-", - "A175468-", - "C175469-", - "C175470-", - "G175471-", - "A175472-", - "G175473-", - "G175474-", - "C175475-", - "G175476-", - "A175477-", - "C175478-", - "T175479-", - "T175480-", - "T175481-", - "G175482-", - "T175483-", - "A175484-", - "T175485-", - "T175486-", - "T175487-", - "T175488-", - "G175489-", - "A175490-", - "A175491-", - "A175492-", - "A175493-", - "T175494-", - "G175495-", - "T175496-", - "T175497-", - "A175498-", - "C175499-", - "T175500-", - "G175501-", - "A175502-", - "A175503-", - "G175504-", - "A175505-", - "A175506-", - "T175507-", - "A175508-", - "T175509-", - "A175510-", - "T175511-", - "A175512-", - "G175513-", - "G175514-", - "C175515-", - "A175516-", - "A175517-", - "T175518-", - "A175519-", - "C175520-", - "A175521-", - "T175522-", - "A175523-", - "T175524-", - "A175525-", - "C175526-", - "A175527-", - "T175528-", - "G175529-", - "T175530-", - "C175531-", - "G175532-", - "T175533-", - "G175534-", - "G175535-", - "A175536-", - "C175537-", - "A175538-", - "C175539-", - "A175540-", - "A175541-", - "C175542-", - "T175543-", - "A175544-", - "T175545-", - "T175546-", - "A175547-", - "T175548-", - "T175549-", - "T175550-", - "T175551-", - "G175552-", - "A175553-", - "T175554-", - "A175555-", - "A175556-", - "A175557-", - "A175558-", - "C175559-", - "T175560-", - "C175561-", - "T175562-", - "T175563-", - "A175564-", - "C175565-", - "A175566-", - "A175567-", - "C175568-", - "T175569-", - "A175570-", - "C175571-", - "A175572-", - "G175573-", - "T175574-", - "A175575-", - "G175576-", - "T175577-", - "A175578-", - "T175579-", - "T175580-", - "G175581-", - "G175582-", - "A175583-", - "G175584-", - "T175585-", - "A175586-", - "A175587-", - "A175588-", - "T175589-", - "A175590-", - "C175591-", - "A175592-", - "C175593-", - "A175594-", - "A175595-", - "T175596-", - "G175597-", - "C175598-", - "A175599-", - "T175600-", - "T175601-", - "T175602-", - "T175603-", - "T175604-", - "A175605-", - "T175606-", - "A175607-", - "T175608-", - "A175609-", - "C175610-", - "A175611-", - "T175612-", - "T175613-", - "A175614-", - "C175615-", - "T175616-", - "G175617-", - "A175618-", - "A175619-", - "T175620-", - "T175621-", - "A175622-", - "T175623-", - "T175624-", - "A175625-", - "T175626-", - "T175627-", - "A175628-", - "T175629-", - "T175630-", - "A175631-", - "A175632-", - "T175633-", - "T175634-", - "A175635-", - "T175636-", - "A175637-", - "T175638-", - "C175639-", - "G175640-", - "T175641-", - "A175642-", - "T175643-", - "T175644-", - "T175645-", - "G175646-", - "T175647-", - "G175648-", - "C175649-", - "T175650-", - "A175651-", - "T175652-", - "A175653-", - "G175654-", - "A175655-", - "A175656-", - "T175657-", - "G175658-", - "G175659-", - "A175660-", - "T175661-", - "G175662-", - "A175663-", - "A175664-", - "G175665-", - "A175666-", - "T175667-", - "A175668-", - "C175669-", - "G175670-", - "C175671-", - "G175672-", - "A175673-", - "C175674-", - "T175675-", - "A175676-", - "T175677-", - "C175678-", - "T175679-", - "A175680-", - "G175681-", - "G175682-", - "T175683-", - "A175684-", - "T175685-", - "T175686-", - "T175687-", - "G175688-", - "T175689-", - "A175690-", - "T175691-", - "C175692-", - "T175693-", - "C175694-", - "A175695-", - "C175696-", - "C175697-", - "G175698-", - "A175699-", - "T175700-", - "A175701-", - "G175702-", - "A175703-", - "G175704-", - "A175705-", - "A175706-", - "C175707-", - "A175708-", - "T175709-", - "A175710-", - "T175711-", - "A175712-", - "A175713-", - "A175714-", - "T175715-", - "G175716-", - "T175717-", - "A175718-", - "G175719-", - "A175720-", - "C175721-", - "T175722-", - "C175723-", - "T175724-", - "A175725-", - "T175726-", - "T175727-", - "A175728-", - "A175729-", - "A175730-", - "C175731-", - "A175732-", - "G175733-", - "T175734-", - "T175735-", - "G175736-", - "T175737-", - "G175738-", - "T175739-", - "A175740-", - "A175741-", - "A175742-", - "A175743-", - "T175744-", - "A175745-", - "T175746-", - "C175747-", - "A175748-", - "G175749-", - "A175750-", - "T175751-", - "C175752-", - "C175753-", - "T175754-", - "A175755-", - "A175756-", - "T175757-", - "G175758-", - "C175759-", - "A175760-", - "T175761-", - "G175762-", - "T175763-", - "T175764-", - "A175765-", - "T175766-", - "A175767-", - "G175768-", - "A175769-", - "T175770-", - "G175771-", - "T175772-", - "G175773-", - "G175774-", - "A175775-", - "T175776-", - "G175777-", - "T175778-", - "A175779-", - "C175780-", - "G175781-", - "G175782-", - "C175783-", - "T175784-", - "T175785-", - "T175786-", - "A175787-", - "C175788-", - "A175789-", - "T175790-", - "G175791-", - "A175792-", - "G175793-", - "T175794-", - "A175795-", - "C175796-", - "T175797-", - "T175798-", - "T175799-", - "T175800-", - "A175801-", - "T175802-", - "A175803-", - "A175804-", - "T175805-", - "T175806-", - "A175807-", - "T175808-", - "A175809-", - "G175810-", - "A175811-", - "T175812-", - "C175813-", - "A175814-", - "G175815-", - "T175816-", - "C175817-", - "A175818-", - "A175819-", - "C175820-", - "G175821-", - "G175822-", - "A175823-", - "A175824-", - "A175825-", - "A175826-", - "T175827-", - "A175828-", - "C175829-", - "A175830-", - "A175831-", - "G175832-", - "T175833-", - "A175834-", - "T175835-", - "A175836-", - "G175837-", - "A175838-", - "T175839-", - "A175840-", - "C175841-", - "A175842-", - "A175843-", - "C175844-", - "G175845-", - "G175846-", - "T175847-", - "T175848-", - "A175849-", - "C175850-", - "T175851-", - "A175852-", - "T175853-", - "C175854-", - "A175855-", - "A175856-", - "T175857-", - "A175858-", - "T175859-", - "T175860-", - "A175861-", - "T175862-", - "T175863-", - "C175864-", - "A175865-", - "T175866-", - "C175867-", - "T175868-", - "A175869-", - "G175870-", - "C175871-", - "G175872-", - "A175873-", - "T175874-", - "T175875-", - "A175876-", - "T175877-", - "G175878-", - "A175879-", - "A175880-", - "A175881-", - "A175882-", - "T175883-", - "T175884-", - "A175885-", - "T175886-", - "A175887-", - "A175888-", - "T175889-", - "G175890-", - "A175891-", - "A175892-", - "T175893-", - "A175894-", - "T175895-", - "T175896-", - "A175897-", - "T175898-", - "T175899-", - "A175900-", - "T175901-", - "G175902-", - "A175903-", - "T175904-", - "G175905-", - "A175906-", - "T175907-", - "T175908-", - "A175909-", - "T175910-", - "G175911-", - "A175912-", - "T175913-", - "A175914-", - "G175915-", - "A175916-", - "A175917-", - "C175918-", - "T175919-", - "G175920-", - "G175921-", - "T175922-", - "A175923-", - "T175924-", - "G175925-", - "A175926-", - "A175927-", - "C175928-", - "A175929-", - "G175930-", - "T175931-", - "G175932-", - "A175933-", - "G175934-", - "A175935-", - "G175936-", - "T175937-", - "G175938-", - "A175939-", - "T175940-", - "A175941-", - "A175942-", - "T175943-", - "A175944-", - "T175945-", - "A175946-", - "T175947-", - "C175948-", - "A175949-", - "A175950-", - "T175951-", - "C175952-", - "A175953-", - "A175954-", - "A175955-", - "A175956-", - "C175957-", - "A175958-", - "G175959-", - "A175960-", - "A175961-", - "T175962-", - "A175963-", - "C175964-", - "G175965-", - "A175966-", - "G175967-", - "A175968-", - "A175969-", - "T175970-", - "G175971-", - "A175972-", - "A175973-", - "T175974-", - "A175975-", - "T175976-", - "G175977-", - "A175978-", - "A175979-", - "T175980-", - "T175981-", - "C175982-", - "T175983-", - "A175984-", - "T175985-", - "G175986-", - "A175987-", - "T175988-", - "G175989-", - "A175990-", - "A175991-", - "A175992-", - "C175993-", - "A175994-", - "C175995-", - "A175996-", - "A175997-", - "G175998-", - "A175999-", - "T176000-", - "C176001-", - "A176002-", - "A176003-", - "A176004-", - "G176005-", - "T176006-", - "A176007-", - "C176008-", - "A176009-", - "C176010-", - "A176011-", - "A176012-", - "C176013-", - "T176014-", - "A176015-", - "G176016-", - "T176017-", - "A176018-", - "G176019-", - "A176020-", - "T176021-", - "T176022-", - "A176023-", - "C176024-", - "G176025-", - "A176026-", - "C176027-", - "A176028-", - "T176029-", - "T176030-", - "A176031-", - "A176032-", - "A176033-", - "C176034-", - "T176035-", - "C176036-", - "A176037-", - "A176038-", - "A176039-", - "A176040-", - "C176041-", - "C176042-", - "A176043-", - "A176044-", - "T176045-", - "G176046-", - "A176047-", - "G176048-", - "G176049-", - "A176050-", - "T176051-", - "G176052-", - "A176053-", - "T176054-", - "T176055-", - "T176056-", - "T176057-", - "G176058-", - "T176059-", - "T176060-", - "G176061-", - "A176062-", - "T176063-", - "G176064-", - "A176065-", - "A176066-", - "T176067-", - "T176068-", - "C176069-", - "T176070-", - "A176071-", - "T176072-", - "G176073-", - "G176074-", - "T176075-", - "T176076-", - "A176077-", - "T176078-", - "G176079-", - "A176080-", - "T176081-", - "A176082-", - "G176083-", - "A176084-", - "T176085-", - "C176086-", - "A176087-", - "G176088-", - "T176089-", - "G176090-", - "G176091-", - "G176092-", - "T176093-", - "G176094-", - "T176095-", - "C176096-", - "C176097-", - "A176098-", - "T176099-", - "G176100-", - "A176101-", - "T176102-", - "T176103-", - "A176104-", - "T176105-", - "A176106-", - "T176107-", - "A176108-", - "G176109-", - "A176110-", - "T176111-", - "G176112-", - "T176113-", - "A176114-", - "T176115-", - "C176116-", - "A176117-", - "A176118-", - "T176119-", - "T176120-", - "A176121-", - "A176122-", - "T176123-", - "A176124-", - "A176125-", - "A176126-", - "G176127-", - "T176128-", - "A176129-", - "G176130-", - "T176131-", - "A176132-", - "T176133-", - "A176134-", - "T176135-", - "G176136-", - "G176137-", - "A176138-", - "A176139-", - "G176140-", - "A176141-", - "G176142-", - "A176143-", - "G176144-", - "T176145-", - "C176146-", - "T176147-", - "C176148-", - "A176149-", - "C176150-", - "G176151-", - "T176152-", - "A176153-", - "A176154-", - "G176155-", - "A176156-", - "T176157-", - "G176158-", - "G176159-", - "T176160-", - "G176161-", - "G176162-", - "G176163-", - "A176164-", - "T176165-", - "A176166-", - "T176167-", - "A176168-", - "T176169-", - "G176170-", - "G176171-", - "C176172-", - "A176173-", - "A176174-", - "G176175-", - "A176176-", - "A176177-", - "C176178-", - "A176179-", - "T176180-", - "A176181-", - "A176182-", - "T176183-", - "G176184-", - "A176185-", - "T176186-", - "G176187-", - "G176188-", - "C176189-", - "G176190-", - "T176191-", - "A176192-", - "T176193-", - "A176194-", - "C176195-", - "A176196-", - "G176197-", - "T176198-", - "A176199-", - "T176200-", - "A176201-", - "G176202-", - "G176203-", - "A176204-", - "A176205-", - "A176206-", - "G176207-", - "G176208-", - "A176209-", - "G176210-", - "T176211-", - "G176212-", - "C176213-", - "A176214-", - "T176215-", - "A176216-", - "G176217-", - "A176218-", - "T176219-", - "A176220-", - "A176221-", - "T176222-", - "A176223-", - "T176224-", - "A176225-", - "T176226-", - "A176227-", - "C176228-", - "G176229-", - "A176230-", - "A176231-", - "G176232-", - "A176233-", - "C176234-", - "A176235-", - "G176236-", - "A176237-", - "C176238-", - "A176239-", - "T176240-", - "A176241-", - "C176242-", - "C176243-", - "G176244-", - "T176245-", - "A176246-", - "G176247-", - "A176248-", - "C176249-", - "G176250-", - "A176251-", - "A176252-", - "T176253-", - "T176254-", - "C176255-", - "T176256-", - "A176257-", - "C176258-", - "A176259-", - "A176260-", - "G176261-", - "A176262-", - "T176263-", - "A176264-", - "G176265-", - "A176266-", - "C176267-", - "A176268-", - "G176269-", - "C176270-", - "G176271-", - "T176272-", - "A176273-", - "T176274-", - "C176275-", - "A176276-", - "G176277-", - "A176278-", - "T176279-", - "G176280-", - "T176281-", - "A176282-", - "G176283-", - "A176284-", - "T176285-", - "G176286-", - "A176287-", - "C176288-", - "G176289-", - "C176290-", - "A176291-", - "G176292-", - "A176293-", - "A176294-", - "C176295-", - "A176296-", - "T176297-", - "A176298-", - "T176299-", - "A176300-", - "T176301-", - "C176302-", - "T176303-", - "C176304-", - "A176305-", - "G176306-", - "A176307-", - "T176308-", - "A176309-", - "A176310-", - "C176311-", - "T176312-", - "A176313-", - "A176314-", - "T176315-", - "G176316-", - "A176317-", - "T176318-", - "G176319-", - "T176320-", - "A176321-", - "T176322-", - "C176323-", - "T176324-", - "A176325-", - "C176326-", - "A176327-", - "C176328-", - "A176329-", - "A176330-", - "A176331-", - "C176332-", - "A176333-", - "T176334-", - "G176335-", - "G176336-", - "G176337-", - "A176338-", - "A176339-", - "A176340-", - "A176341-", - "G176342-", - "A176343-", - "A176344-", - "A176345-", - "T176346-", - "C176347-", - "A176348-", - "G176349-", - "A176350-", - "G176351-", - "T176352-", - "T176353-", - "A176354-", - "G176355-", - "A176356-", - "T176357-", - "A176358-", - "G176359-", - "A176360-", - "T176361-", - "A176362-", - "C176363-", - "A176364-", - "T176365-", - "G176366-", - "G176367-", - "A176368-", - "A176369-", - "A176370-", - "T176371-", - "G176372-", - "T176373-", - "A176374-", - "T176375-", - "C176376-", - "C176377-", - "T176378-", - "C176379-", - "G176380-", - "T176381-", - "C176382-", - "A176383-", - "T176384-", - "A176385-", - "G176386-", - "A176387-", - "T176388-", - "A176389-", - "T176390-", - "G176391-", - "G176392-", - "T176393-", - "A176394-", - "A176395-", - "G176396-", - "C176397-", - "A176398-", - "T176399-", - "T176400-", - "C176401-", - "T176402-", - "G176403-", - "T176404-", - "C176405-", - "T176406-", - "T176407-", - "T176408-", - "A176409-", - "A176410-", - "G176411-", - "G176412-", - "G176413-", - "A176414-", - "T176415-", - "T176416-", - "T176417-", - "T176418-", - "C176419-", - "T176420-", - "G176421-", - "A176422-", - "C176423-", - "A176424-", - "A176425-", - "A176426-", - "G176427-", - "T176428-", - "T176429-", - "A176430-", - "G176431-", - "A176432-", - "A176433-", - "A176434-", - "A176435-", - "A176436-", - "A176437-", - "T176438-", - "G176439-", - "A176440-", - "T176441-", - "T176442-", - "T176443-", - "A176444-", - "G176445-", - "A176446-", - "C176447-", - "A176448-", - "T176449-", - "G176450-", - "A176451-", - "A176452-", - "C176453-", - "G176454-", - "T176455-", - "G176456-", - "G176457-", - "T176458-", - "A176459-", - "A176460-", - "A176461-", - "A176462-", - "G176463-", - "A176464-", - "A176465-", - "T176466-", - "T176467-", - "A176468-", - "C176469-", - "T176470-", - "T176471-", - "T176472-", - "C176473-", - "T176474-", - "A176475-", - "A176476-", - "C176477-", - "G176478-", - "G176479-", - "T176480-", - "G176481-", - "C176482-", - "A176483-", - "T176484-", - "C176485-", - "T176486-", - "C176487-", - "T176488-", - "A176489-", - "A176490-", - "C176491-", - "A176492-", - "A176493-", - "T176494-", - "C176495-", - "A176496-", - "A176497-", - "G176498-", - "G176499-", - "A176500-", - "T176501-", - "A176502-", - "G176503-", - "C176504-", - "A176505-", - "G176506-", - "T176507-", - "A176508-", - "A176509-", - "T176510-", - "A176511-", - "A176512-", - "G176513-", - "G176514-", - "A176515-", - "T176516-", - "C176517-", - "C176518-", - "A176519-", - "A176520-", - "T176521-", - "T176522-", - "G176523-", - "C176524-", - "T176525-", - "G176526-", - "T176527-", - "T176528-", - "T176529-", - "A176530-", - "T176531-", - "T176532-", - "T176533-", - "T176534-", - "A176535-", - "G176536-", - "A176537-", - "A176538-", - "G176539-", - "A176540-", - "A176541-", - "C176542-", - "A176543-", - "A176544-", - "T176545-", - "A176546-", - "A176547-", - "T176548-", - "G176549-", - "A176550-", - "A176551-", - "T176552-", - "T176553-", - "T176554-", - "A176555-", - "G176556-", - "A176557-", - "A176558-", - "A176559-", - "T176560-", - "G176561-", - "A176562-", - "T176563-", - "T176564-", - "G176565-", - "A176566-", - "T176567-", - "A176568-", - "T176569-", - "C176570-", - "A176571-", - "T176572-", - "T176573-", - "A176574-", - "A176575-", - "C176576-", - "A176577-", - "A176578-", - "A176579-", - "C176580-", - "A176581-", - "T176582-", - "A176583-", - "C176584-", - "A176585-", - "A176586-", - "C176587-", - "T176588-", - "A176589-", - "T176590-", - "C176591-", - "T176592-", - "A176593-", - "T176594-", - "G176595-", - "A176596-", - "A176597-", - "C176598-", - "G176599-", - "C176600-", - "A176601-", - "G176602-", - "G176603-", - "T176604-", - "A176605-", - "T176606-", - "A176607-", - "T176608-", - "A176609-", - "G176610-", - "T176611-", - "A176612-", - "C176613-", - "A176614-", - "C176615-", - "T176616-", - "C176617-", - "C176618-", - "T176619-", - "A176620-", - "T176621-", - "C176622-", - "T176623-", - "A176624-", - "A176625-", - "A176626-", - "A176627-", - "A176628-", - "A176629-", - "T176630-", - "T176631-", - "A176632-", - "T176633-", - "A176634-", - "G176635-", - "A176636-", - "A176637-", - "A176638-", - "T176639-", - "T176640-", - "T176641-", - "C176642-", - "G176643-", - "A176644-", - "T176645-", - "T176646-", - "A176647-", - "T176648-", - "C176649-", - "C176650-", - "A176651-", - "T176652-", - "T176653-", - "T176654-", - "T176655-", - "T176656-", - "C176657-", - "A176658-", - "G176659-", - "A176660-", - "A176661-", - "A176662-", - "G176663-", - "T176664-", - "T176665-", - "A176666-", - "G176667-", - "T176668-", - "T176669-", - "T176670-", - "T176671-", - "G176672-", - "A176673-", - "C176674-", - "T176675-", - "A176676-", - "A176677-", - "T176678-", - "A176679-", - "A176680-", - "A176681-", - "C176682-", - "A176683-", - "T176684-", - "T176685-", - "G176686-", - "T176687-", - "C176688-", - "T176689-", - "C176690-", - "A176691-", - "A176692-", - "C176693-", - "A176694-", - "A176695-", - "T176696-", - "T176697-", - "A176698-", - "T176699-", - "T176700-", - "G176701-", - "T176702-", - "A176703-", - "A176704-", - "T176705-", - "A176706-", - "T176707-", - "A176708-", - "A176709-", - "G176710-", - "C176711-", - "G176712-", - "A176713-", - "C176714-", - "G176715-", - "G176716-", - "C176717-", - "A176718-", - "A176719-", - "A176720-", - "T176721-", - "A176722-", - "T176723-", - "G176724-", - "G176725-", - "A176726-", - "A176727-", - "C176728-", - "A176729-", - "C176730-", - "C176731-", - "A176732-", - "C176733-", - "T176734-", - "A176735-", - "C176736-", - "A176737-", - "T176738-", - "A176739-", - "T176740-", - "A176741-", - "T176742-", - "T176743-", - "A176744-", - "G176745-", - "C176746-", - "A176747-", - "T176748-", - "C176749-", - "T176750-", - "A176751-", - "A176752-", - "T176753-", - "A176754-", - "A176755-", - "A176756-", - "A176757-", - "A176758-", - "A176759-", - "A176760-", - "T176761-", - "A176762-", - "A176763-", - "T176764-", - "A176765-", - "A176766-", - "C176767-", - "T176768-", - "C176769-", - "C176770-", - "T176771-", - "A176772-", - "A176773-", - "T176774-", - "T176775-", - "A176776-", - "C176777-", - "A176778-", - "T176779-", - "G176780-", - "A176781-", - "A176782-", - "G176783-", - "T176784-", - "T176785-", - "A176786-", - "T176787-", - "T176788-", - "A176789-", - "G176790-", - "T176791-", - "G176792-", - "T176793-", - "A176794-", - "T176795-", - "A176796-", - "A176797-", - "C176798-", - "G176799-", - "G176800-", - "A176801-", - "A176802-", - "A176803-", - "T176804-", - "G176805-", - "A176806-", - "T176807-", - "A176808-", - "T176809-", - "A176810-", - "A176811-", - "A176812-", - "C176813-", - "G176814-", - "C176815-", - "A176816-", - "C176817-", - "G176818-", - "A176819-", - "G176820-", - "G176821-", - "T176822-", - "G176823-", - "A176824-", - "A176825-", - "G176826-", - "A176827-", - "T176828-", - "A176829-", - "C176830-", - "A176831-", - "C176832-", - "A176833-", - "A176834-", - "A176835-", - "T176836-", - "G176837-", - "C176838-", - "G176839-", - "A176840-", - "A176841-", - "C176842-", - "T176843-", - "C176844-", - "C176845-", - "A176846-", - "T176847-", - "T176848-", - "A176849-", - "C176850-", - "A176851-", - "C176852-", - "A176853-", - "A176854-", - "A176855-", - "T176856-", - "A176857-", - "T176858-", - "T176859-", - "T176860-", - "G176861-", - "T176862-", - "G176863-", - "T176864-", - "A176865-", - "A176866-", - "A176867-", - "T176868-", - "T176869-", - "T176870-", - "G176871-", - "T176872-", - "A176873-", - "T176874-", - "A176875-", - "T176876-", - "C176877-", - "A176878-", - "T176879-", - "A176880-", - "A176881-", - "T176882-", - "A176883-", - "T176884-", - "T176885-", - "G176886-", - "A176887-", - "A176888-", - "T176889-", - "A176890-", - "T176891-", - "G176892-", - "G176893-", - "T176894-", - "A176895-", - "T176896-", - "C176897-", - "C176898-", - "G176899-", - "A176900-", - "T176901-", - "A176902-", - "C176903-", - "T176904-", - "A176905-", - "T176906-", - "A176907-", - "A176908-", - "T176909-", - "G176910-", - "A176911-", - "A176912-", - "A176913-", - "A176914-", - "G176915-", - "A176916-", - "T176917-", - "T176918-", - "A176919-", - "T176920-", - "A176921-", - "G176922-", - "A176923-", - "C176924-", - "G176925-", - "C176926-", - "A176927-", - "T176928-", - "T176929-", - "T176930-", - "A176931-", - "T176932-", - "A176933-", - "G176934-", - "A176935-", - "G176936-", - "T176937-", - "T176938-", - "A176939-", - "G176940-", - "G176941-", - "A176942-", - "G176943-", - "C176944-", - "C176945-", - "G176946-", - "A176947-", - "T176948-", - "C176949-", - "T176950-", - "A176951-", - "A176952-", - "C176953-", - "T176954-", - "A176955-", - "T176956-", - "T176957-", - "C176958-", - "C176959-", - "A176960-", - "A176961-", - "A176962-", - "T176963-", - "G176964-", - "A176965-", - "C176966-", - "G176967-", - "A176968-", - "T176969-", - "G176970-", - "G176971-", - "A176972-", - "A176973-", - "T176974-", - "G176975-", - "A176976-", - "T176977-", - "A176978-", - "C176979-", - "C176980-", - "A176981-", - "G176982-", - "T176983-", - "A176984-", - "G176985-", - "T176986-", - "T176987-", - "T176988-", - "A176989-", - "C176990-", - "T176991-", - "G176992-", - "T176993-", - "A176994-", - "T176995-", - "A176996-", - "C176997-", - "A176998-", - "C176999-", - "T177000-", - "C177001-", - "A177002-", - "A177003-", - "A177004-", - "T177005-", - "G177006-", - "C177007-", - "C177008-", - "G177009-", - "A177010-", - "A177011-", - "T177012-", - "A177013-", - "T177014-", - "G177015-", - "G177016-", - "T177017-", - "T177018-", - "A177019-", - "T177020-", - "A177021-", - "A177022-", - "C177023-", - "A177024-", - "A177025-", - "T177026-", - "A177027-", - "T177028-", - "T177029-", - "A177030-", - "C177031-", - "T177032-", - "A177033-", - "A177034-", - "C177035-", - "A177036-", - "T177037-", - "A177038-", - "A177039-", - "A177040-", - "G177041-", - "A177042-", - "T177043-", - "A177044-", - "A177045-", - "T177046-", - "A177047-", - "C177048-", - "G177049-", - "T177050-", - "A177051-", - "A177052-", - "A177053-", - "C177054-", - "T177055-", - "A177056-", - "C177057-", - "T177058-", - "T177059-", - "A177060-", - "A177061-", - "T177062-", - "C177063-", - "T177064-", - "T177065-", - "A177066-", - "G177067-", - "T177068-", - "A177069-", - "G177070-", - "A177071-", - "C177072-", - "A177073-", - "T177074-", - "G177075-", - "C177076-", - "G177077-", - "T177078-", - "C177079-", - "A177080-", - "C177081-", - "A177082-", - "T177083-", - "A177084-", - "A177085-", - "T177086-", - "C177087-", - "T177088-", - "A177089-", - "T177090-", - "T177091-", - "T177092-", - "A177093-", - "G177094-", - "A177095-", - "G177096-", - "A177097-", - "T177098-", - "C177099-", - "G177100-", - "A177101-", - "G177102-", - "T177103-", - "C177104-", - "A177105-", - "T177106-", - "G177107-", - "C177108-", - "A177109-", - "C177110-", - "G177111-", - "A177112-", - "T177113-", - "T177114-", - "A177115-", - "T177116-", - "A177117-", - "T177118-", - "A177119-", - "A177120-", - "G177121-", - "T177122-", - "A177123-", - "A177124-", - "T177125-", - "A177126-", - "C177127-", - "A177128-", - "T177129-", - "A177130-", - "T177131-", - "A177132-", - "T177133-", - "T177134-", - "G177135-", - "A177136-", - "T177137-", - "C177138-", - "T177139-", - "T177140-", - "G177141-", - "A177142-", - "G177143-", - "T177144-", - "G177145-", - "T177146-", - "T177147-", - "T177148-", - "A177149-", - "G177150-", - "A177151-", - "T177152-", - "A177153-", - "T177154-", - "C177155-", - "A177156-", - "T177157-", - "T177158-", - "A177159-", - "G177160-", - "A177161-", - "T177162-", - "C177163-", - "A177164-", - "C177165-", - "T177166-", - "T177167-", - "G177168-", - "A177169-", - "T177170-", - "G177171-", - "G177172-", - "G177173-", - "T177174-", - "A177175-", - "C177176-", - "G177177-", - "A177178-", - "T177179-", - "A177180-", - "T177181-", - "T177182-", - "A177183-", - "A177184-", - "T177185-", - "T177186-", - "G177187-", - "T177188-", - "T177189-", - "A177190-", - "C177191-", - "T177192-", - "T177193-", - "T177194-", - "G177195-", - "A177196-", - "A177197-", - "G177198-", - "G177199-", - "A177200-", - "C177201-", - "G177202-", - "T177203-", - "A177204-", - "C177205-", - "A177206-", - "C177207-", - "C177208-", - "A177209-", - "C177210-", - "T177211-", - "T177212-", - "C177213-", - "A177214-", - "T177215-", - "T177216-", - "G177217-", - "C177218-", - "G177219-", - "C177220-", - "T177221-", - "A177222-", - "T177223-", - "A177224-", - "C177225-", - "A177226-", - "A177227-", - "T177228-", - "A177229-", - "T177230-", - "A177231-", - "A177232-", - "C177233-", - "T177234-", - "T177235-", - "C177236-", - "A177237-", - "C177238-", - "T177239-", - "C177240-", - "A177241-", - "G177242-", - "A177243-", - "T177244-", - "T177245-", - "G177246-", - "C177247-", - "T177248-", - "G177249-", - "A177250-", - "G177251-", - "T177252-", - "A177253-", - "C177254-", - "T177255-", - "T177256-", - "A177257-", - "T177258-", - "T177259-", - "A177260-", - "G177261-", - "A177262-", - "T177263-", - "C177264-", - "G177265-", - "A177266-", - "G177267-", - "G177268-", - "A177269-", - "G177270-", - "C177271-", - "T177272-", - "G177273-", - "A177274-", - "T177275-", - "A177276-", - "T177277-", - "A177278-", - "T177279-", - "C177280-", - "A177281-", - "T177282-", - "T177283-", - "A177284-", - "A177285-", - "A177286-", - "G177287-", - "A177288-", - "C177289-", - "A177290-", - "G177291-", - "A177292-", - "C177293-", - "G177294-", - "A177295-", - "T177296-", - "G177297-", - "G177298-", - "T177299-", - "A177300-", - "A177301-", - "A177302-", - "A177303-", - "C177304-", - "T177305-", - "G177306-", - "T177307-", - "A177308-", - "T177309-", - "T177310-", - "T177311-", - "G177312-", - "A177313-", - "T177314-", - "T177315-", - "T177316-", - "A177317-", - "T177318-", - "C177319-", - "G177320-", - "T177321-", - "T177322-", - "A177323-", - "T177324-", - "G177325-", - "T177326-", - "A177327-", - "G177328-", - "T177329-", - "T177330-", - "A177331-", - "C177332-", - "A177333-", - "T177334-", - "T177335-", - "C177336-", - "C177337-", - "T177338-", - "C177339-", - "T177340-", - "T177341-", - "A177342-", - "A177343-", - "A177344-", - "T177345-", - "G177346-", - "G177347-", - "A177348-", - "C177349-", - "T177350-", - "A177351-", - "G177352-", - "C177353-", - "T177354-", - "T177355-", - "T177356-", - "T177357-", - "T177358-", - "G177359-", - "A177360-", - "T177361-", - "T177362-", - "A177363-", - "G177364-", - "T177365-", - "C177366-", - "G177367-", - "T177368-", - "C177369-", - "T177370-", - "A177371-", - "C177372-", - "C177373-", - "G177374-", - "C177375-", - "C177376-", - "T177377-", - "A177378-", - "A177379-", - "A177380-", - "A177381-", - "G177382-", - "T177383-", - "G177384-", - "T177385-", - "C177386-", - "A177387-", - "T177388-", - "A177389-", - "T177390-", - "G177391-", - "C177392-", - "T177393-", - "C177394-", - "A177395-", - "C177396-", - "T177397-", - "G177398-", - "A177399-", - "C177400-", - "T177401-", - "A177402-", - "A177403-", - "C177404-", - "C177405-", - "A177406-", - "T177407-", - "A177408-", - "T177409-", - "A177410-", - "A177411-", - "T177412-", - "A177413-", - "G177414-", - "A177415-", - "T177416-", - "T177417-", - "A177418-", - "T177419-", - "G177420-", - "T177421-", - "T177422-", - "C177423-", - "T177424-", - "T177425-", - "A177426-", - "C177427-", - "G177428-", - "A177429-", - "A177430-", - "C177431-", - "A177432-", - "A177433-", - "T177434-", - "A177435-", - "G177436-", - "A177437-", - "C177438-", - "G177439-", - "T177440-", - "A177441-", - "T177442-", - "T177443-", - "A177444-", - "T177445-", - "T177446-", - "T177447-", - "G177448-", - "G177449-", - "C177450-", - "A177451-", - "G177452-", - "A177453-", - "G177454-", - "T177455-", - "C177456-", - "A177457-", - "A177458-", - "A177459-", - "T177460-", - "G177461-", - "A177462-", - "T177463-", - "T177464-", - "A177465-", - "A177466-", - "T177467-", - "A177468-", - "A177469-", - "G177470-", - "T177471-", - "A177472-", - "C177473-", - "G177474-", - "T177475-", - "A177476-", - "C177477-", - "T177478-", - "G177479-", - "T177480-", - "T177481-", - "A177482-", - "C177483-", - "T177484-", - "G177485-", - "G177486-", - "A177487-", - "C177488-", - "C177489-", - "C177490-", - "A177491-", - "T177492-", - "C177493-", - "C177494-", - "T177495-", - "T177496-", - "T177497-", - "T177498-", - "A177499-", - "T177500-", - "T177501-", - "A177502-", - "T177503-", - "A177504-", - "G177505-", - "A177506-", - "T177507-", - "T177508-", - "C177509-", - "A177510-", - "G177511-", - "A177512-", - "A177513-", - "A177514-", - "T177515-", - "G177516-", - "T177517-", - "T177518-", - "A177519-", - "T177520-", - "C177521-", - "G177522-", - "A177523-", - "A177524-", - "A177525-", - "A177526-", - "C177527-", - "A177528-", - "A177529-", - "A177530-", - "T177531-", - "T177532-", - "A177533-", - "G177534-", - "A177535-", - "C177536-", - "C177537-", - "A177538-", - "A177539-", - "T177540-", - "A177541-", - "C177542-", - "A177543-", - "A177544-", - "T177545-", - "A177546-", - "A177547-", - "T177548-", - "C177549-", - "G177550-", - "T177551-", - "T177552-", - "A177553-", - "T177554-", - "A177555-", - "A177556-", - "T177557-", - "A177558-", - "T177559-", - "G177560-", - "T177561-", - "T177562-", - "C177563-", - "G177564-", - "A177565-", - "A177566-", - "C177567-", - "A177568-", - "C177569-", - "G177570-", - "A177571-", - "T177572-", - "A177573-", - "G177574-", - "G177575-", - "G177576-", - "A177577-", - "C177578-", - "G177579-", - "T177580-", - "T177581-", - "A177582-", - "A177583-", - "T177584-", - "G177585-", - "A177586-", - "A177587-", - "A177588-", - "A177589-", - "G177590-", - "T177591-", - "A177592-", - "T177593-", - "G177594-", - "G177595-", - "C177596-", - "A177597-", - "A177598-", - "A177599-", - "G177600-", - "T177601-", - "C177602-", - "T177603-", - "T177604-", - "A177605-", - "C177606-", - "A177607-", - "T177608-", - "G177609-", - "A177610-", - "C177611-", - "C177612-", - "T177613-", - "C177614-", - "G177615-", - "A177616-", - "T177617-", - "A177618-", - "C177619-", - "A177620-", - "T177621-", - "A177622-", - "T177623-", - "A177624-", - "T177625-", - "C177626-", - "A177627-", - "A177628-", - "G177629-", - "G177630-", - "A177631-", - "T177632-", - "G177633-", - "T177634-", - "A177635-", - "C177636-", - "A177637-", - "A177638-", - "G177639-", - "T177640-", - "A177641-", - "T177642-", - "T177643-", - "A177644-", - "A177645-", - "A177646-", - "A177647-", - "T177648-", - "C177649-", - "T177650-", - "A177651-", - "C177652-", - "T177653-", - "T177654-", - "C177655-", - "C177656-", - "A177657-", - "T177658-", - "C177659-", - "A177660-", - "C177661-", - "T177662-", - "A177663-", - "A177664-", - "T177665-", - "A177666-", - "A177667-", - "T177668-", - "A177669-", - "T177670-", - "A177671-", - "A177672-", - "C177673-", - "A177674-", - "C177675-", - "T177676-", - "A177677-", - "T177678-", - "A177679-", - "C177680-", - "G177681-", - "A177682-", - "C177683-", - "A177684-", - "C177685-", - "T177686-", - "A177687-", - "T177688-", - "T177689-", - "A177690-", - "T177691-", - "A177692-", - "A177693-", - "A177694-", - "T177695-", - "A177696-", - "A177697-", - "T177698-", - "A177699-", - "A177700-", - "G177701-", - "T177702-", - "C177703-", - "A177704-", - "G177705-", - "A177706-", - "G177707-", - "T177708-", - "T177709-", - "T177710-", - "C177711-", - "C177712-", - "T177713-", - "A177714-", - "T177715-", - "A177716-", - "C177717-", - "G177718-", - "T177719-", - "C177720-", - "G177721-", - "T177722-", - "G177723-", - "T177724-", - "A177725-", - "A177726-", - "A177727-", - "C177728-", - "G177729-", - "A177730-", - "C177731-", - "A177732-", - "A177733-", - "A177734-", - "C177735-", - "A177736-", - "A177737-", - "T177738-", - "T177739-", - "A177740-", - "A177741-", - "T177742-", - "T177743-", - "A177744-", - "A177745-", - "T177746-", - "C177747-", - "T177748-", - "C177749-", - "A177750-", - "T177751-", - "A177752-", - "A177753-", - "A177754-", - "A177755-", - "T177756-", - "C177757-", - "C177758-", - "A177759-", - "A177760-", - "T177761-", - "A177762-", - "C177763-", - "A177764-", - "T177765-", - "A177766-", - "T177767-", - "C177768-", - "A177769-", - "T177770-", - "A177771-", - "A177772-", - "T177773-", - "C177774-", - "T177775-", - "T177776-", - "A177777-", - "T177778-", - "C177779-", - "G177780-", - "A177781-", - "A177782-", - "A177783-", - "A177784-", - "A177785-", - "G177786-", - "T177787-", - "T177788-", - "A177789-", - "T177790-", - "T177791-", - "A177792-", - "A177793-", - "A177794-", - "A177795-", - "A177796-", - "T177797-", - "A177798-", - "C177799-", - "A177800-", - "T177801-", - "T177802-", - "A177803-", - "G177804-", - "A177805-", - "G177806-", - "A177807-", - "A177808-", - "A177809-", - "T177810-", - "A177811-", - "T177812-", - "A177813-", - "C177814-", - "T177815-", - "T177816-", - "T177817-", - "A177818-", - "A177819-", - "C177820-", - "T177821-", - "A177822-", - "A177823-", - "T177824-", - "A177825-", - "T177826-", - "A177827-", - "G177828-", - "T177829-", - "C177830-", - "C177831-", - "T177832-", - "C177833-", - "G177834-", - "A177835-", - "G177836-", - "T177837-", - "A177838-", - "T177839-", - "A177840-", - "T177841-", - "G177842-", - "A177843-", - "T177844-", - "C177845-", - "T177846-", - "C177847-", - "A177848-", - "T177849-", - "C177850-", - "T177851-", - "C177852-", - "G177853-", - "A177854-", - "T177855-", - "C177856-", - "T177857-", - "C177858-", - "A177859-", - "A177860-", - "T177861-", - "C177862-", - "A177863-", - "T177864-", - "C177865-", - "T177866-", - "T177867-", - "A177868-", - "T177869-", - "T177870-", - "T177871-", - "G177872-", - "A177873-", - "G177874-", - "T177875-", - "C177876-", - "G177877-", - "T177878-", - "A177879-", - "T177880-", - "T177881-", - "C177882-", - "C177883-", - "T177884-", - "A177885-", - "A177886-", - "T177887-", - "G177888-", - "A177889-", - "G177890-", - "A177891-", - "T177892-", - "A177893-", - "T177894-", - "T177895-", - "A177896-", - "C177897-", - "T177898-", - "C177899-", - "G177900-", - "A177901-", - "A177902-", - "A177903-", - "T177904-", - "A177905-", - "T177906-", - "T177907-", - "A177908-", - "T177909-", - "A177910-", - "T177911-", - "A177912-", - "A177913-", - "A177914-", - "C177915-", - "T177916-", - "C177917-", - "G177918-", - "A177919-", - "C177920-", - "A177921-", - "T177922-", - "G177923-", - "T177924-", - "A177925-", - "C177926-", - "G177927-", - "A177928-", - "T177929-", - "T177930-", - "T177931-", - "A177932-", - "C177933-", - "G177934-", - "T177935-", - "A177936-", - "A177937-", - "T177938-", - "C177939-", - "T177940-", - "A177941-", - "T177942-", - "A177943-", - "T177944-", - "A177945-", - "C177946-", - "A177947-", - "A177948-", - "G177949-", - "A177950-", - "T177951-", - "A177952-", - "T177953-", - "A177954-", - "T177955-", - "G177956-", - "A177957-", - "G177958-", - "A177959-", - "G177960-", - "A177961-", - "G177962-", - "A177963-", - "A177964-", - "T177965-", - "G177966-", - "A177967-", - "T177968-", - "A177969-", - "T177970-", - "C177971-", - "A177972-", - "C177973-", - "A177974-", - "G177975-", - "A177976-", - "G177977-", - "T177978-", - "A177979-", - "T177980-", - "C177981-", - "A177982-", - "T177983-", - "A177984-", - "T177985-", - "A177986-", - "G177987-", - "A177988-", - "G177989-", - "A177990-", - "A177991-", - "T177992-", - "A177993-", - "C177994-", - "G177995-", - "A177996-", - "G177997-", - "G177998-", - "T177999-", - "C178000-", - "T178001-", - "G178002-", - "T178003-", - "T178004-", - "T178005-", - "C178006-", - "T178007-", - "A178008-", - "C178009-", - "A178010-", - "C178011-", - "A178012-", - "G178013-", - "A178014-", - "C178015-", - "A178016-", - "T178017-", - "G178018-", - "A178019-", - "A178020-", - "T178021-", - "A178022-", - "A178023-", - "T178024-", - "G178025-", - "A178026-", - "A178027-", - "T178028-", - "A178029-", - "C178030-", - "A178031-", - "C178032-", - "A178033-", - "T178034-", - "A178035-", - "C178036-", - "A178037-", - "A178038-", - "C178039-", - "G178040-", - "T178041-", - "T178042-", - "T178043-", - "T178044-", - "T178045-", - "T178046-", - "T178047-", - "T178048-", - "A178049-", - "A178050-", - "T178051-", - "C178052-", - "T178053-", - "T178054-", - "A178055-", - "G178056-", - "A178057-", - "T178058-", - "A178059-", - "T178060-", - "A178061-", - "A178062-", - "C178063-", - "A178064-", - "C178065-", - "T178066-", - "A178067-", - "A178068-", - "T178069-", - "T178070-", - "A178071-", - "C178072-", - "A178073-", - "T178074-", - "C178075-", - "A178076-", - "A178077-", - "G178078-", - "A178079-", - "T178080-", - "T178081-", - "A178082-", - "T178083-", - "A178084-", - "T178085-", - "A178086-", - "T178087-", - "T178088-", - "G178089-", - "A178090-", - "A178091-", - "A178092-", - "T178093-", - "C178094-", - "G178095-", - "T178096-", - "A178097-", - "A178098-", - "T178099-", - "T178100-", - "T178101-", - "G178102-", - "A178103-", - "G178104-", - "T178105-", - "T178106-", - "G178107-", - "T178108-", - "C178109-", - "T178110-", - "G178111-", - "A178112-", - "T178113-", - "C178114-", - "A178115-", - "T178116-", - "C178117-", - "A178118-", - "T178119-", - "G178120-", - "G178121-", - "A178122-", - "T178123-", - "A178124-", - "T178125-", - "C178126-", - "G178127-", - "A178128-", - "A178129-", - "A178130-", - "A178131-", - "T178132-", - "A178133-", - "A178134-", - "T178135-", - "A178136-", - "T178137-", - "A178138-", - "C178139-", - "G178140-", - "T178141-", - "A178142-", - "A178143-", - "C178144-", - "A178145-", - "T178146-", - "T178147-", - "A178148-", - "G178149-", - "C178150-", - "A178151-", - "A178152-", - "T178153-", - "C178154-", - "T178155-", - "T178156-", - "T178157-", - "T178158-", - "A178159-", - "G178160-", - "A178161-", - "T178162-", - "G178163-", - "A178164-", - "T178165-", - "T178166-", - "G178167-", - "A178168-", - "T178169-", - "A178170-", - "T178171-", - "A178172-", - "T178173-", - "T178174-", - "A178175-", - "T178176-", - "T178177-", - "A178178-", - "T178179-", - "G178180-", - "C178181-", - "G178182-", - "A178183-", - "T178184-", - "G178185-", - "T178186-", - "A178187-", - "A178188-", - "T178189-", - "C178190-", - "A178191-", - "T178192-", - "A178193-", - "A178194-", - "C178195-", - "T178196-", - "A178197-", - "T178198-", - "C178199-", - "G178200-", - "G178201-", - "A178202-", - "G178203-", - "A178204-", - "T178205-", - "G178206-", - "T178207-", - "A178208-", - "G178209-", - "A178210-", - "A178211-", - "A178212-", - "T178213-", - "T178214-", - "A178215-", - "A178216-", - "A178217-", - "G178218-", - "C178219-", - "G178220-", - "C178221-", - "A178222-", - "T178223-", - "A178224-", - "A178225-", - "A178226-", - "A178227-", - "C178228-", - "T178229-", - "A178230-", - "T178231-", - "T178232-", - "T178233-", - "T178234-", - "G178235-", - "G178236-", - "T178237-", - "T178238-", - "G178239-", - "C178240-", - "C178241-", - "G178242-", - "G178243-", - "A178244-", - "T178245-", - "C178246-", - "T178247-", - "A178248-", - "C178249-", - "G178250-", - "T178251-", - "A178252-", - "T178253-", - "T178254-", - "T178255-", - "T178256-", - "A178257-", - "A178258-", - "A178259-", - "A178260-", - "C178261-", - "A178262-", - "A178263-", - "T178264-", - "G178265-", - "T178266-", - "T178267-", - "C178268-", - "A178269-", - "C178270-", - "A178271-", - "A178272-", - "C178273-", - "A178274-", - "T178275-", - "C178276-", - "T178277-", - "A178278-", - "T178279-", - "G178280-", - "A178281-", - "T178282-", - "A178283-", - "G178284-", - "C178285-", - "G178286-", - "A178287-", - "G178288-", - "A178289-", - "G178290-", - "A178291-", - "T178292-", - "C178293-", - "T178294-", - "A178295-", - "G178296-", - "C178297-", - "A178298-", - "A178299-", - "C178300-", - "T178301-", - "A178302-", - "G178303-", - "A178304-", - "G178305-", - "T178306-", - "A178307-", - "A178308-", - "A178309-", - "T178310-", - "A178311-", - "T178312-", - "A178313-", - "C178314-", - "A178315-", - "G178316-", - "A178317-", - "T178318-", - "G178319-", - "T178320-", - "T178321-", - "C178322-", - "G178323-", - "A178324-", - "T178325-", - "A178326-", - "A178327-", - "A178328-", - "G178329-", - "A178330-", - "T178331-", - "G178332-", - "C178333-", - "C178334-", - "G178335-", - "T178336-", - "C178337-", - "A178338-", - "A178339-", - "A178340-", - "A178341-", - "A178342-", - "T178343-", - "A178344-", - "T178345-", - "T178346-", - "G178347-", - "T178348-", - "A178349-", - "C178350-", - "A178351-", - "G178352-", - "T178353-", - "A178354-", - "C178355-", - "T178356-", - "T178357-", - "A178358-", - "T178359-", - "A178360-", - "C178361-", - "A178362-", - "A178363-", - "T178364-", - "A178365-", - "G178366-", - "G178367-", - "T178368-", - "A178369-", - "T178370-", - "A178371-", - "T178372-", - "A178373-", - "A178374-", - "G178375-", - "T178376-", - "T178377-", - "C178378-", - "T178379-", - "A178380-", - "T178381-", - "G178382-", - "A178383-", - "A178384-", - "T178385-", - "G178386-", - "T178387-", - "G178388-", - "A178389-", - "T178390-", - "A178391-", - "G178392-", - "A178393-", - "C178394-", - "A178395-", - "T178396-", - "A178397-", - "T178398-", - "T178399-", - "A178400-", - "A178401-", - "A178402-", - "A178403-", - "T178404-", - "G178405-", - "C178406-", - "A178407-", - "C178408-", - "C178409-", - "G178410-", - "A178411-", - "C178412-", - "T178413-", - "A178414-", - "A178415-", - "G178416-", - "A178417-", - "A178418-", - "C178419-", - "G178420-", - "T178421-", - "A178422-", - "A178423-", - "A178424-", - "A178425-", - "C178426-", - "G178427-", - "A178428-", - "A178429-", - "C178430-", - "T178431-", - "A178432-", - "T178433-", - "A178434-", - "G178435-", - "A178436-", - "A178437-", - "T178438-", - "G178439-", - "T178440-", - "T178441-", - "A178442-", - "T178443-", - "A178444-", - "C178445-", - "A178446-", - "A178447-", - "T178448-", - "G178449-", - "G178450-", - "G178451-", - "T178452-", - "G178453-", - "A178454-", - "T178455-", - "G178456-", - "A178457-", - "T178458-", - "A178459-", - "A178460-", - "G178461-", - "T178462-", - "A178463-", - "G178464-", - "A178465-", - "A178466-", - "G178467-", - "A178468-", - "T178469-", - "G178470-", - "T178471-", - "T178472-", - "A178473-", - "C178474-", - "C178475-", - "C178476-", - "G178477-", - "A178478-", - "T178479-", - "A178480-", - "T178481-", - "A178482-", - "C178483-", - "C178484-", - "C178485-", - "A178486-", - "T178487-", - "A178488-", - "G178489-", - "C178490-", - "A178491-", - "T178492-", - "T178493-", - "A178494-", - "T178495-", - "C178496-", - "T178497-", - "A178498-", - "G178499-", - "T178500-", - "T178501-", - "A178502-", - "T178503-", - "G178504-", - "G178505-", - "C178506-", - "A178507-", - "T178508-", - "G178509-", - "T178510-", - "G178511-", - "T178512-", - "G178513-", - "T178514-", - "A178515-", - "T178516-", - "T178517-", - "A178518-", - "G178519-", - "A178520-", - "T178521-", - "C178522-", - "A178523-", - "A178524-", - "T178525-", - "A178526-", - "C178527-", - "A178528-", - "T178529-", - "A178530-", - "T178531-", - "A178532-", - "C178533-", - "A178534-", - "T178535-", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-", - "A178554-", - "C178555-", - "A178556-", - "C178557-", - "T178558-", - "G178559-", - "A178560-", - "T178561-", - "T178562-", - "A178563-", - "T178564-", - "A178565-", - "C178566-", - "A178567-", - "T178568-", - "C178569-", - "G178570-", - "G178571-", - "T178572-", - "A178573-", - "C178574-", - "A178575-", - "T178576-", - "A178577-", - "C178578-", - "A178579-", - "G178580-", - "T178581-", - "A178582-", - "A178583-", - "A178584-", - "T178585-", - "A178586-", - "G178587-", - "C178588-", - "A178589-", - "T178590-", - "A178591-", - "G178592-", - "A178593-", - "T178594-", - "A178595-", - "T178596-", - "G178597-", - "G178598-", - "A178599-", - "G178600-", - "G178601-", - "A178602-", - "G178603-", - "G178604-", - "A178605-", - "T178606-", - "A178607-", - "C178608-", - "A178609-", - "A178610-", - "A178611-", - "T178612-", - "A178613-", - "T178614-", - "T178615-", - "T178616-", - "C178617-", - "A178618-", - "A178619-", - "A178620-", - "T178621-", - "A178622-", - "A178623-", - "A178624-", - "G178625-", - "T178626-", - "T178627-", - "A178628-", - "T178629-", - "G178630-", - "A178631-", - "G178632-", - "A178633-", - "T178634-", - "A178635-", - "C178636-", - "G178637-", - "C178638-", - "G178639-", - "C178640-", - "T178641-", - "G178642-", - "T178643-", - "C178644-", - "A178645-", - "A178646-", - "T178647-", - "A178648-", - "A178649-", - "T178650-", - "A178651-", - "T178652-", - "A178653-", - "T178654-", - "G178655-", - "G178656-", - "A178657-", - "A178658-", - "G178659-", - "A178660-", - "C178661-", - "A178662-", - "T178663-", - "T178664-", - "A178665-", - "C178666-", - "C178667-", - "T178668-", - "A178669-", - "A178670-", - "C178671-", - "T178672-", - "T178673-", - "C178674-", - "T178675-", - "G178676-", - "A178677-", - "A178678-", - "C178679-", - "T178680-", - "G178681-", - "G178682-", - "A178683-", - "A178684-", - "C178685-", - "T178686-", - "A178687-", - "T178688-", - "A178689-", - "A178690-", - "A178691-", - "T178692-", - "C178693-", - "C178694-", - "A178695-", - "G178696-", - "G178697-", - "C178698-", - "T178699-", - "C178700-", - "T178701-", - "C178702-", - "G178703-", - "C178704-", - "A178705-", - "T178706-", - "A178707-", - "A178708-", - "A178709-", - "G178710-", - "A178711-", - "T178712-", - "G178713-", - "A178714-", - "A178715-", - "T178716-", - "A178717-", - "T178718-", - "A178719-", - "T178720-", - "A178721-", - "T178722-", - "G178723-", - "T178724-", - "T178725-", - "G178726-", - "T178727-", - "A178728-", - "T178729-", - "G178730-", - "C178731-", - "G178732-", - "A178733-", - "C178734-", - "A178735-", - "T178736-", - "C178737-", - "A178738-", - "A178739-", - "A178740-", - "G178741-", - "A178742-", - "T178743-", - "G178744-", - "A178745-", - "A178746-", - "A178747-", - "A178748-", - "A178749-", - "A178750-", - "T178751-", - "G178752-", - "T178753-", - "T178754-", - "A178755-", - "A178756-", - "G178757-", - "A178758-", - "C178759-", - "T178760-", - "T178761-", - "A178762-", - "T178763-", - "A178764-", - "T178765-", - "A178766-", - "T178767-", - "T178768-", - "T178769-", - "A178770-", - "G178771-", - "A178772-", - "T178773-", - "A178774-", - "T178775-", - "A178776-", - "A178777-", - "C178778-", - "A178779-", - "C178780-", - "G178781-", - "A178782-", - "A178783-", - "T178784-", - "A178785-", - "T178786-", - "G178787-", - "T178788-", - "A178789-", - "T178790-", - "G178791-", - "A178792-", - "C178793-", - "G178794-", - "G178795-", - "A178796-", - "T178797-", - "G178798-", - "G178799-", - "G178800-", - "A178801-", - "A178802-", - "T178803-", - "T178804-", - "G178805-", - "G178806-", - "T178807-", - "A178808-", - "A178809-", - "C178810-", - "G178811-", - "A178812-", - "T178813-", - "G178814-", - "A178815-", - "C178816-", - "A178817-", - "G178818-", - "A178819-", - "A178820-", - "A178821-", - "G178822-", - "C178823-", - "A178824-", - "G178825-", - "A178826-", - "T178827-", - "T178828-", - "G178829-", - "T178830-", - "C178831-", - "A178832-", - "G178833-", - "C178834-", - "T178835-", - "C178836-", - "T178837-", - "G178838-", - "C178839-", - "A178840-", - "T178841-", - "A178842-", - "C178843-", - "T178844-", - "A178845-", - "T178846-", - "T178847-", - "C178848-", - "T178849-", - "T178850-", - "C178851-", - "A178852-", - "T178853-", - "G178854-", - "A178855-", - "C178856-", - "A178857-", - "A178858-", - "T178859-", - "A178860-", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-", - "G178879-", - "T178880-", - "T178881-", - "A178882-", - "T178883-", - "G178884-", - "A178885-", - "A178886-", - "G178887-", - "C178888-", - "G178889-", - "T178890-", - "A178891-", - "T178892-", - "A178893-", - "T178894-", - "G178895-", - "T178896-", - "T178897-", - "A178898-", - "C178899-", - "A178900-", - "A178901-", - "G178902-", - "A178903-", - "T178904-", - "A178905-", - "C178906-", - "A178907-", - "T178908-", - "T178909-", - "T178910-", - "A178911-", - "A178912-", - "T178913-", - "G178914-", - "T178915-", - "G178916-", - "C178917-", - "T178918-", - "T178919-", - "A178920-", - "C178921-", - "G178922-", - "G178923-", - "A178924-", - "A178925-", - "C178926-", - "A178927-", - "T178928-", - "A178929-", - "T178930-", - "A178931-", - "T178932-", - "T178933-", - "T178934-", - "A178935-", - "G178936-", - "A178937-", - "A178938-", - "A178939-", - "C178940-", - "A178941-", - "T178942-", - "C178943-", - "T178944-", - "A178945-", - "C178946-", - "T178947-", - "A178948-", - "A178949-", - "C178950-", - "G178951-", - "A178952-", - "T178953-", - "T178954-", - "T178955-", - "T178956-", - "T178957-", - "T178958-", - "A178959-", - "T178960-", - "G178961-", - "C178962-", - "T178963-", - "T178964-", - "G178965-", - "T178966-", - "A178967-", - "T178968-", - "T178969-", - "A178970-", - "T178971-", - "T178972-", - "A178973-", - "A178974-", - "T178975-", - "G178976-", - "G178977-", - "T178978-", - "A178979-", - "T178980-", - "G178981-", - "T178982-", - "A178983-", - "A178984-", - "T178985-", - "A178986-", - "T178987-", - "G178988-", - "A178989-", - "T178990-", - "T178991-", - "T178992-", - "A178993-", - "A178994-", - "T178995-", - "T178996-", - "G178997-", - "A178998-", - "T178999-", - "T179000-", - "G179001-", - "T179002-", - "G179003-", - "T179004-", - "A179005-", - "C179006-", - "A179007-", - "C179008-", - "G179009-", - "A179010-", - "T179011-", - "A179012-", - "C179013-", - "C179014-", - "A179015-", - "A179016-", - "T179017-", - "T179018-", - "T179019-", - "G179020-", - "T179021-", - "C179022-", - "G179023-", - "A179024-", - "G179025-", - "T179026-", - "A179027-", - "T179028-", - "G179029-", - "A179030-", - "A179031-", - "T179032-", - "A179033-", - "C179034-", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "G181049-", - "T181102-", - "A181103-", - "T181104-", - "A181105-", - "T181106-", - "T181107-", - "C181108-", - "C181109-", - "T181110-", - "A181246-", - "T183553-", - "A183554-", - "C183555-", - "T187073-", - "T187207-", - "T187770-", - "T189739-", - "A190198-", - "C190199-", - "A190396-", - "A192435-", - "A192436-", - "G192437-", - "T192438-", - "C192439-", - "A192440-", - "T192441-", - "A192442-", - "A192443-", - "G192444-", - "T192445-", - "T192446-", - "A192447-", - "G192448-", - "T192449-", - "T192450-", - "A192451-", - "A192452-", - "G192453-", - "T192454-", - "C192455-", - "A192456-", - "T192457-", - "A192458-", - "A192459-", - "G192460-", - "T192461-", - "T192462-", - "A192463-", - "G192464-", - "T192465-", - "T192466-", - "A192467-", - "A192468-", - "G192469-", - "T192470-", - "C192471-", - "A192472-", - "T192473-", - "A192474-", - "A192475-", - "G192476-", - "T192477-", - "T192478-", - "A192479-", - "G192480-", - "T192481-", - "T192482-", - "A192483-", - "A192484-", - "G192485-", - "T192486-", - "C192487-", - "A192488-", - "T192489-", - "A192490-", - "A192491-", - "G192492-", - "T192493-", - "T192494-", - "A192495-", - "G192496-", - "T192497-", - "T192498-", - "A192499-", - "A192500-", - "G192501-", - "T192502-", - "C192503-", - "A192504-", - "T192505-", - "A192506-", - "A192507-", - "G192508-", - "T192509-", - "T192510-", - "A192511-", - "G192512-", - "T192513-", - "T192514-", - "A192515-", - "A192516-", - "G192517-", - "T193611C" - ], - "OPG003": [ - "Y337H" - ], - "OPG021": [ - "K230X", - "*243X" - ], - "OPG022": [ - "K121X", - "*127X" - ], - "OPG029": [ - "D153-", - "D154-" - ], - "OPG031": [ - "G258-" - ], - "OPG044": [ - "E145X", - "*150X" - ], - "OPG049": [ - "R314X", - "H315X", - "*319X" - ], - "OPG050": [ - "F72X", - "*76X" - ], - "OPG054": [ - "K144X", - "*440X" - ], - "OPG061": [ - "K49X", - "*232X" - ], - "OPG063": [ - "F65X", - "*480X" - ], - "OPG064": [ - "L261X", - "*738X" - ], - "OPG075": [ - "F75X", - "*109X" - ], - "OPG078": [ - "F56X", - "*74X" - ], - "OPG082": [ - "I362X", - "*383X" - ], - "OPG084": [ - "F10X", - "*677X" - ], - "OPG085": [ - "S565X", - "K585X", - "*592X" - ], - "OPG092": [ - "N351X", - "*372X" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG104": [ - "N60X", - "*134X" - ], - "OPG105": [ - "R281X", - "*1287X" - ], - "OPG109": [ - "F116X", - "K206X", - "K683X", - "*796X" - ], - "OPG114": [ - "K9X", - "I10X", - "*147X" - ], - "OPG117": [ - "F501X", - "*786X" - ], - "OPG122": [ - "F106X", - "*249X" - ], - "OPG123": [ - "N570X", - "*632X" - ], - "OPG124": [ - "N205X", - "*288X" - ], - "OPG125": [ - "G499X", - "*552X" - ], - "OPG133": [ - "G144X", - "*711X" - ], - "OPG136": [ - "N877X", - "*892X" - ], - "OPG138": [ - "N6X", - "*191X" - ], - "OPG145": [ - "L14X", - "L258X", - "*493X" - ], - "OPG149": [ - "I184X", - "K185X", - "*188X" - ], - "OPG150": [ - "*383X" - ], - "OPG151": [ - "K2X", - "K946X", - "*1165X" - ], - "OPG154": [ - "K57X", - "*111X" - ], - "OPG155": [ - "F8X", - "*147X" - ], - "OPG157": [ - "Q61X", - "H62X", - "*79X" - ], - "OPG159": [ - "N113X", - "N114-", - "N115-", - "Y116X", - "*146X" - ], - "OPG164": [ - "L227X", - "*229X" - ], - "OPG170": [ - "I218X", - "*222X" - ], - "OPG173": [ - "K34X", - "E57X", - "*75X" - ], - "OPG180": [ - "K243X", - "S554X", - "*560X" - ], - "OPG188": [ - "K436X", - "*504X" - ], - "OPG191": [ - "Y165X", - "F166X", - "*169X" - ], - "OPG193": [ - "T261X", - "*268X" - ], - "OPG197": [ - "D17-", - "S18-", - "V36X", - "E37-", - "D38-", - "I39-", - "M40-", - "N41-", - "E42-", - "I43X", - "*101X" - ], - "OPG198": [ - "Q229X", - "*283X" - ], - "OPG204": [ - "M1-", - "K2-", - "M3-", - "K4-", - "M5-", - "M6-", - "V7-", - "R8-", - "I9-", - "Y10-", - "F11-", - "V12-", - "S13-", - "L14-", - "S15-", - "L16-", - "L17-", - "L18-", - "F19-", - "H20-", - "S21-", - "Y22-", - "A23-", - "I24-", - "D25-", - "I26-", - "E27-", - "N28-", - "E29-", - "I30-", - "T31-", - "E32-", - "F33-", - "F34-", - "N35-", - "K36-", - "M37-", - "R38-", - "D39-", - "T40-", - "L41-", - "P42-", - "A43-", - "K44-", - "D45-", - "S46-", - "K47-", - "W48-", - "L49-", - "N50-", - "P51-", - "V52-", - "C53-", - "M54-", - "F55-", - "G56-", - "G57-", - "T58-", - "M59-", - "N60-", - "D61-", - "M62-", - "A63-", - "A64-", - "L65-", - "G66-", - "E67-", - "P68-", - "F69-", - "S70-", - "A71-", - "K72-", - "C73-", - "P74-", - "P75-", - "I76-", - "E77-", - "D78-", - "S79-", - "L80-", - "L81-", - "S82-", - "H83-", - "R84-", - "Y85-", - "K86-", - "D87-", - "Y88-", - "V89-", - "V90-", - "K91-", - "W92-", - "E93-", - "R94-", - "L95-", - "E96-", - "K97-", - "N98-", - "R99-", - "R100-", - "R101-", - "Q102-", - "V103-", - "S104-", - "N105-", - "K106-", - "R107-", - "V108-", - "K109-", - "H110-", - "G111-", - "D112-", - "L113-", - "W114-", - "I115-", - "A116-", - "N117-", - "Y118-", - "T119-", - "S120-", - "K121-", - "F122-", - "S123-", - "N124-", - "R125-", - "R126-", - "Y127-", - "L128-", - "C129-", - "T130-", - "V131-", - "T132-", - "T133-", - "K134-", - "N135-", - "G136-", - "D137-", - "C138-", - "V139-", - "Q140-", - "G141-", - "V142-", - "V143-", - "R144-", - "S145-", - "H146-", - "V147-", - "W148-", - "K149-", - "P150-", - "S151-", - "S152-", - "C153-", - "I154-", - "P155-", - "K156-", - "T157-", - "Y158-", - "E159-", - "L160-", - "G161-", - "T162-", - "Y163-", - "D164-", - "K165-", - "Y166-", - "G167-", - "I168-", - "D169-", - "L170-", - "Y171-", - "C172-", - "G173-", - "I174-", - "L175-", - "Y176-", - "A177-", - "N178-", - "H179-", - "Y180-", - "N181-", - "N182-", - "I183-", - "T184-", - "W185-", - "Y186-", - "K187-", - "D188-", - "N189-", - "K190-", - "E191-", - "I192-", - "N193-", - "I194-", - "D195-", - "D196-", - "F197-", - "K198-", - "Y199-", - "S200-", - "Q201-", - "A202-", - "G203-", - "K204-", - "E205-", - "L206-", - "I207-", - "I208-", - "H209-", - "N210-", - "P211-", - "E212-", - "L213-", - "E214-", - "D215-", - "S216-", - "G217-", - "R218-", - "Y219-", - "D220-", - "C221-", - "Y222-", - "V223-", - "H224-", - "Y225-", - "D226-", - "D227-", - "V228-", - "R229-", - "I230-", - "K231-", - "N232-", - "D233-", - "I234-", - "V235-", - "V236-", - "S237-", - "R238-", - "C239-", - "K240-", - "I241-", - "L242-", - "T243-", - "V244-", - "I245-", - "P246-", - "S247-", - "Q248-", - "D249-", - "H250-", - "R251-", - "F252-", - "K253-", - "L254-", - "I255-", - "L256-", - "D257-", - "P258-", - "K259-", - "I260-", - "N261-", - "V262-", - "T263-", - "I264-", - "G265-", - "E266-", - "P267-", - "A268-", - "N269-", - "I270-", - "T271-", - "C272-", - "S273-", - "A274-", - "V275-", - "S276-", - "T277-", - "S278-", - "L279-", - "F280-", - "V281-", - "D282-", - "D283-", - "V284-", - "L285-", - "I286-", - "E287-", - "W288-", - "E289-", - "N290-", - "P291-", - "S292-", - "G293-", - "W294-", - "I295-", - "I296-", - "G297-", - "L298-", - "D299-", - "F300-", - "G301-", - "V302-", - "Y303-", - "S304-", - "I305-", - "L306-", - "T307-", - "S308-", - "R309-", - "G310-", - "G311-", - "I312-", - "T313-", - "E314-", - "A315-", - "T316-", - "L317-", - "Y318-", - "F319-", - "E320-", - "N321-", - "V322-", - "T323-", - "E324-", - "E325-", - "Y326-", - "I327-", - "G328-", - "N329-", - "T330-", - "Y331-", - "T332-", - "C333-", - "R334-", - "G335-", - "H336-", - "N337-", - "Y338-", - "Y339-", - "F340-", - "D341-", - "K342-", - "T343-", - "L344-", - "T345-", - "T346-", - "T347-", - "V348-", - "V349-", - "L350-", - "E351-", - "*352-" - ], - "OPG205": [ - "M1-", - "D2-", - "E3-", - "D4-", - "T5-", - "R6-", - "L7-", - "S8-", - "R9-", - "Y10-", - "L11-", - "Y12-", - "L13-", - "T14-", - "D15-", - "R16-", - "E17-", - "H18-", - "I19-", - "N20-", - "V21-", - "D22-", - "S23-", - "I24-", - "K25-", - "Q26-", - "L27-", - "C28-", - "K29-", - "I30-", - "S31-", - "D32-", - "P33-", - "N34-", - "A35-", - "C36-", - "Y37-", - "R38-", - "C39-", - "G40-", - "C41-", - "T42-", - "A43-", - "L44-", - "H45-", - "E46-", - "Y47-", - "F48-", - "Y49-", - "N50-", - "Y51-", - "R52-", - "S53-", - "V54-", - "N55-", - "G56-", - "K57-", - "Y58-", - "K59-", - "Y60-", - "R61-", - "Y62-", - "N63-", - "G64-", - "Y65-", - "Y66-", - "Q67-", - "Y68-", - "Y69-", - "S70-", - "S71-", - "S72-", - "D73-", - "Y74-", - "E75-", - "N76-", - "Y77-", - "N78-", - "E79-", - "Y80-", - "Y81-", - "Y82-", - "D83-", - "D84-", - "Y85-", - "D86-", - "R87-", - "T88-", - "G89-", - "M90-", - "N91-", - "S92-", - "E93-", - "S94-", - "D95-", - "N96-", - "I97-", - "S98-", - "I99-", - "K100-", - "T101-", - "E102-", - "Y103-", - "E104-", - "N105-", - "E106-", - "Y107-", - "E108-", - "F109-", - "Y110-", - "D111-", - "E112-", - "T113-", - "Q114-", - "D115-", - "Q116-", - "S117-", - "T118-", - "Q119-", - "L120-", - "V121-", - "D122-", - "Y123-", - "D124-", - "I125-", - "K126-", - "L127-", - "K128-", - "T129-", - "N130-", - "E131-", - "D132-", - "D133-", - "F134-", - "V135-", - "D136-", - "E137-", - "F138-", - "Y139-", - "G140-", - "Y141-", - "D142-", - "R143-", - "S144-", - "V145-", - "G146-", - "V147-", - "H148-", - "D149-", - "Y150-", - "I151-", - "D152-", - "V153-", - "S154-", - "I155-", - "N156-", - "K157-", - "V158-", - "V159-", - "Y160-", - "G161-", - "R162-", - "E163-", - "S164-", - "H165-", - "V166-", - "R167-", - "W168-", - "W169-", - "D170-", - "I171-", - "W172-", - "Q173-", - "E174-", - "H175-", - "N176-", - "D177-", - "G178-", - "V179-", - "Y180-", - "S181-", - "I182-", - "G183-", - "K184-", - "E185-", - "C186-", - "I187-", - "D188-", - "N189-", - "I190-", - "Y191-", - "E192-", - "D193-", - "R194-", - "H195-", - "T196-", - "V197-", - "D198-", - "E199-", - "F200-", - "Y201-", - "K202-", - "I203-", - "D204-", - "S205-", - "V206-", - "S207-", - "D208-", - "V209-", - "D210-", - "D211-", - "A212-", - "E213-", - "H214-", - "I215-", - "S216-", - "Q217-", - "I218-", - "T219-", - "N220-", - "D221-", - "V222-", - "S223-", - "T224-", - "Q225-", - "T226-", - "W227-", - "E228-", - "K229-", - "K230-", - "S231-", - "E232-", - "L233-", - "D234-", - "R235-", - "Y236-", - "M237-", - "E238-", - "M239-", - "Y240-", - "P241-", - "R242-", - "H243-", - "R244-", - "Y245-", - "G246-", - "K247-", - "H248-", - "S249-", - "V250-", - "F251-", - "K252-", - "G253-", - "F254-", - "S255-", - "D256-", - "K257-", - "V258-", - "R259-", - "K260-", - "N261-", - "D262-", - "L263-", - "D264-", - "M265-", - "N266-", - "V267-", - "V268-", - "K269-", - "E270-", - "L271-", - "L272-", - "S273-", - "N274-", - "G275-", - "A276-", - "S277-", - "L278-", - "T279-", - "I280-", - "K281-", - "D282-", - "S283-", - "S284-", - "N285-", - "K286-", - "D287-", - "P288-", - "I289-", - "A290-", - "V291-", - "Y292-", - "F293-", - "R294-", - "R295-", - "T296-", - "I297-", - "M298-", - "N299-", - "L300-", - "E301-", - "M302-", - "I303-", - "D304-", - "I305-", - "I306-", - "N307-", - "K308-", - "H309-", - "T310-", - "T311-", - "I312-", - "Y313-", - "E314-", - "R315-", - "R316-", - "Y317-", - "I318-", - "V319-", - "H320-", - "S321-", - "Y322-", - "L323-", - "K324-", - "N325-", - "Y326-", - "R327-", - "N328-", - "F329-", - "D330-", - "Y331-", - "P332-", - "F333-", - "F334-", - "R335-", - "K336-", - "L337-", - "V338-", - "L339-", - "T340-", - "N341-", - "K342-", - "H343-", - "C344-", - "L345-", - "N346-", - "N347-", - "Y348-", - "C349-", - "N350-", - "I351-", - "S352-", - "D353-", - "G354-", - "K355-", - "Y356-", - "G357-", - "T358-", - "P359-", - "L360-", - "H361-", - "I362-", - "L363-", - "A364-", - "S365-", - "N366-", - "K367-", - "K368-", - "I369-", - "I370-", - "T371-", - "P372-", - "N373-", - "Y374-", - "M375-", - "K376-", - "L377-", - "L378-", - "V379-", - "Y380-", - "N381-", - "G382-", - "N383-", - "D384-", - "I385-", - "N386-", - "A387-", - "R388-", - "G389-", - "E390-", - "D391-", - "T392-", - "Q393-", - "M394-", - "R395-", - "T396-", - "P397-", - "L398-", - "H399-", - "K400-", - "Y401-", - "L402-", - "C403-", - "K404-", - "F405-", - "V406-", - "Y407-", - "H408-", - "N409-", - "I410-", - "E411-", - "Y412-", - "G413-", - "I414-", - "R415-", - "Y416-", - "Y417-", - "N418-", - "E419-", - "K420-", - "I421-", - "I422-", - "D423-", - "A424-", - "F425-", - "I426-", - "E427-", - "L428-", - "G429-", - "A430-", - "D431-", - "L432-", - "T433-", - "I434-", - "P435-", - "N436-", - "D437-", - "D438-", - "G439-", - "M440-", - "I441-", - "P442-", - "V443-", - "V444-", - "Y445-", - "C446-", - "I447-", - "H448-", - "S449-", - "N450-", - "A451-", - "E452-", - "Y453-", - "G454-", - "Y455-", - "N456-", - "N457-", - "I458-", - "T459-", - "N460-", - "I461-", - "K462-", - "I463-", - "I464-", - "R465-", - "K466-", - "L467-", - "L468-", - "N469-", - "L470-", - "S471-", - "R472-", - "H473-", - "A474-", - "S475-", - "H476-", - "N477-", - "L478-", - "F479-", - "R480-", - "D481-", - "R482-", - "V483-", - "M484-", - "H485-", - "D486-", - "Y487-", - "I488-", - "S489-", - "N490-", - "T491-", - "Y492-", - "I493-", - "D494-", - "L495-", - "E496-", - "C497-", - "L498-", - "D499-", - "I500-", - "I501-", - "R502-", - "S503-", - "L504-", - "D505-", - "G506-", - "Y507-", - "D508-", - "I509-", - "N510-", - "C511-", - "Y512-", - "F513-", - "E514-", - "G515-", - "R516-", - "T517-", - "P518-", - "L519-", - "H520-", - "C521-", - "A522-", - "I523-", - "Q524-", - "Y525-", - "N526-", - "F527-", - "T528-", - "Q529-", - "I530-", - "A531-", - "E532-", - "Y533-", - "L534-", - "L535-", - "D536-", - "R537-", - "G538-", - "A539-", - "D540-", - "I541-", - "S542-", - "L543-", - "K544-", - "T545-", - "D546-", - "D547-", - "G548-", - "K549-", - "T550-", - "V551-", - "F552-", - "D553-", - "L554-", - "S555-", - "L556-", - "C557-", - "S558-", - "Y559-", - "I560-", - "P561-", - "L562-", - "K563-", - "W564-", - "T565-", - "S566-", - "F567-", - "L568-", - "I569-", - "S570-", - "R571-", - "L572-", - "P573-", - "P574-", - "K575-", - "S576-", - "V577-", - "I578-", - "C579-", - "S580-", - "L581-", - "T582-", - "N583-", - "H584-", - "I585-", - "I586-", - "D587-", - "Y588-", - "V589-", - "L590-", - "T591-", - "N592-", - "N593-", - "R594-", - "R595-", - "I596-", - "I597-", - "W598-", - "Q599-", - "S600-", - "Q601-", - "M602-", - "I603-", - "N604-", - "K605-", - "Y606-", - "V607-", - "L608-", - "L609-", - "L610-", - "D611-", - "P612-", - "S613-", - "F614-", - "Y615-", - "Y616-", - "R617-", - "F618-", - "R619-", - "N620-", - "V621-", - "I622-", - "E623-", - "N624-", - "K625-", - "L626-", - "D627-", - "Q628-", - "Y629-", - "N630-", - "N631-", - "R632-", - "Y633-", - "N634-", - "M635-", - "F636-", - "E637-", - "H638-", - "D639-", - "R640-", - "D641-", - "V642-", - "N643-", - "E644-", - "K645-", - "Y646-", - "G647-", - "K648-", - "V649-", - "L650-", - "H651-", - "D652-", - "L653-", - "D654-", - "T655-", - "Y656-", - "I657-", - "K658-", - "D659-", - "V660-", - "Q661-", - "V662-", - "L663-", - "K664-", - "S665-", - "T666-", - "S667-", - "I668-", - "T669-", - "N670-", - "N671-", - "I672-", - "T673-", - "L674-", - "Y675-", - "D676-", - "T677-", - "I678-", - "I679-", - "N680-", - "N681-", - "K682-", - "S683-", - "E684-", - "F685-", - "P686-", - "I687-", - "R688-", - "R689-", - "V690-", - "N691-", - "D692-", - "K693-", - "Q694-", - "L695-", - "I696-", - "N697-", - "L698-", - "I699-", - "K700-", - "S701-", - "N702-", - "T703-", - "Y704-", - "H705-", - "N706-", - "L707-", - "I708-", - "E709-", - "K710-", - "V711-", - "I712-", - "K713-", - "N714-", - "T715-", - "L716-", - "E717-", - "K718-", - "Y719-", - "T720-", - "L721-", - "T722-", - "N723-", - "I724-", - "V725-", - "L726-", - "E727-", - "Y728-", - "M729-", - "I730-", - "S731-", - "S732-", - "R733-", - "S734-", - "Q735-", - "S736-", - "S737-", - "Y738-", - "L739-", - "S740-", - "R741-", - "I742-", - "P743-", - "N744-", - "E745-", - "I746-", - "L747-", - "L748-", - "E749-", - "I750-", - "L751-", - "Y752-", - "K753-", - "L754-", - "D755-", - "M756-", - "Y757-", - "D758-", - "L759-", - "R760-", - "N761-", - "L762-", - "Y763-", - "T764-", - "R765-", - "Y766-", - "M767-", - "R768-", - "E769-", - "N770-", - "D771-", - "I772-", - "T773-", - "E774-", - "Y775-", - "H776-", - "I777-", - "E778-", - "N779-", - "T780-", - "R781-", - "S782-", - "V783-", - "S784-", - "T785-", - "Q786-", - "T787-", - "*788-" - ], - "OPG209": [ - "G178X", - "*191X" - ], - "OPG210": [ - "L733X", - "L734X", - "*1881X" - ] - }, - "labels": { - "aa": "OPG003: Y337H; OPG021: K230X, *243X; OPG022: K121X, *127X; OPG029: D153-, D154-; OPG031: G258-; OPG044: E145X, *150X; OPG049: R314X, H315X, *319X; OPG050: F72X, *76X; OPG054: K144X, *440X; OPG061: K49X, *232X; OPG063: F65X, *480X; OPG064: L261X, *738X; OPG075: F75X, *109X; OPG078: F56X, *74X; OPG082: I362X, *383X; OPG084: F10X, *677X; OPG085: S565X, K585X, *592X; OPG092: N351X, *372X; OPG097: K266X, *345X; OPG104: N60X, *134X; OPG105: R281X, *1287X; OPG109: F116X, K206X, K683X, *796X; OPG114: K9X, I10X, *147X; OPG117: F501X, *786X; OPG122: F106X, *249X; OPG123: N570X, *632X; OPG124: N205X, *288X; OPG125: G499X, *552X; OPG133: G144X, *711X; OPG136: N877X, *892X; OPG138: N6X, *191X; OPG145: L14X, L258X, *493X; OPG149: I184X, K185X, *188X; OPG150: *383X; OPG151: K2X, K946X, *1165X; OPG154: K57X, *111X; OPG155: F8X, *147X; OPG157: Q61X, H62X, *79X; OPG159: N113X, N114-, N115-, Y116X, *146X; OPG164: L227X, *229X; OPG170: I218X, *222X; OPG173: K34X, E57X, *75X; OPG180: K243X, S554X, *560X; OPG188: K436X, *504X; OPG191: Y165X, F166X, *169X; OPG193: T261X, *268X; OPG197: D17-, S18-, V36X, E37-, D38-, I39-, M40-, N41-, E42-, I43X, *101X; OPG198: Q229X, *283X; OPG204: M1-, K2-, M3-, K4-, M5-, M6-, V7-, R8-, I9-, Y10-, F11-, V12-, S13-, L14-, S15-, L16-, L17-, L18-, F19-, H20-, S21-, Y22-, A23-, I24-, D25-, I26-, E27-, N28-, E29-, I30-, T31-, E32-, F33-, F34-, N35-, K36-, M37-, R38-, D39-, T40-, L41-, P42-, A43-, K44-, D45-, S46-, K47-, W48-, L49-, N50-, P51-, V52-, C53-, M54-, F55-, G56-, G57-, T58-, M59-, N60-, D61-, M62-, A63-, A64-, L65-, G66-, E67-, P68-, F69-, S70-, A71-, K72-, C73-, P74-, P75-, I76-, E77-, D78-, S79-, L80-, L81-, S82-, H83-, R84-, Y85-, K86-, D87-, Y88-, V89-, V90-, K91-, W92-, E93-, R94-, L95-, E96-, K97-, N98-, R99-, R100-, R101-, Q102-, V103-, S104-, N105-, K106-, R107-, V108-, K109-, H110-, G111-, D112-, L113-, W114-, I115-, A116-, N117-, Y118-, T119-, S120-, K121-, F122-, S123-, N124-, R125-, R126-, Y127-, L128-, C129-, T130-, V131-, T132-, T133-, K134-, N135-, G136-, D137-, C138-, V139-, Q140-, G141-, V142-, V143-, R144-, S145-, H146-, V147-, W148-, K149-, P150-, S151-, S152-, C153-, I154-, P155-, K156-, T157-, Y158-, E159-, L160-, G161-, T162-, Y163-, D164-, K165-, Y166-, G167-, I168-, D169-, L170-, Y171-, C172-, G173-, I174-, L175-, Y176-, A177-, N178-, H179-, Y180-, N181-, N182-, I183-, T184-, W185-, Y186-, K187-, D188-, N189-, K190-, E191-, I192-, N193-, I194-, D195-, D196-, F197-, K198-, Y199-, S200-, Q201-, A202-, G203-, K204-, E205-, L206-, I207-, I208-, H209-, N210-, P211-, E212-, L213-, E214-, D215-, S216-, G217-, R218-, Y219-, D220-, C221-, Y222-, V223-, H224-, Y225-, D226-, D227-, V228-, R229-, I230-, K231-, N232-, D233-, I234-, V235-, V236-, S237-, R238-, C239-, K240-, I241-, L242-, T243-, V244-, I245-, P246-, S247-, Q248-, D249-, H250-, R251-, F252-, K253-, L254-, I255-, L256-, D257-, P258-, K259-, I260-, N261-, V262-, T263-, I264-, G265-, E266-, P267-, A268-, N269-, I270-, T271-, C272-, S273-, A274-, V275-, S276-, T277-, S278-, L279-, F280-, V281-, D282-, D283-, V284-, L285-, I286-, E287-, W288-, E289-, N290-, P291-, S292-, G293-, W294-, I295-, I296-, G297-, L298-, D299-, F300-, G301-, V302-, Y303-, S304-, I305-, L306-, T307-, S308-, R309-, G310-, G311-, I312-, T313-, E314-, A315-, T316-, L317-, Y318-, F319-, E320-, N321-, V322-, T323-, E324-, E325-, Y326-, I327-, G328-, N329-, T330-, Y331-, T332-, C333-, R334-, G335-, H336-, N337-, Y338-, Y339-, F340-, D341-, K342-, T343-, L344-, T345-, T346-, T347-, V348-, V349-, L350-, E351-, *352-; OPG205: M1-, D2-, E3-, D4-, T5-, R6-, L7-, S8-, R9-, Y10-, L11-, Y12-, L13-, T14-, D15-, R16-, E17-, H18-, I19-, N20-, V21-, D22-, S23-, I24-, K25-, Q26-, L27-, C28-, K29-, I30-, S31-, D32-, P33-, N34-, A35-, C36-, Y37-, R38-, C39-, G40-, C41-, T42-, A43-, L44-, H45-, E46-, Y47-, F48-, Y49-, N50-, Y51-, R52-, S53-, V54-, N55-, G56-, K57-, Y58-, K59-, Y60-, R61-, Y62-, N63-, G64-, Y65-, Y66-, Q67-, Y68-, Y69-, S70-, S71-, S72-, D73-, Y74-, E75-, N76-, Y77-, N78-, E79-, Y80-, Y81-, Y82-, D83-, D84-, Y85-, D86-, R87-, T88-, G89-, M90-, N91-, S92-, E93-, S94-, D95-, N96-, I97-, S98-, I99-, K100-, T101-, E102-, Y103-, E104-, N105-, E106-, Y107-, E108-, F109-, Y110-, D111-, E112-, T113-, Q114-, D115-, Q116-, S117-, T118-, Q119-, L120-, V121-, D122-, Y123-, D124-, I125-, K126-, L127-, K128-, T129-, N130-, E131-, D132-, D133-, F134-, V135-, D136-, E137-, F138-, Y139-, G140-, Y141-, D142-, R143-, S144-, V145-, G146-, V147-, H148-, D149-, Y150-, I151-, D152-, V153-, S154-, I155-, N156-, K157-, V158-, V159-, Y160-, G161-, R162-, E163-, S164-, H165-, V166-, R167-, W168-, W169-, D170-, I171-, W172-, Q173-, E174-, H175-, N176-, D177-, G178-, V179-, Y180-, S181-, I182-, G183-, K184-, E185-, C186-, I187-, D188-, N189-, I190-, Y191-, E192-, D193-, R194-, H195-, T196-, V197-, D198-, E199-, F200-, Y201-, K202-, I203-, D204-, S205-, V206-, S207-, D208-, V209-, D210-, D211-, A212-, E213-, H214-, I215-, S216-, Q217-, I218-, T219-, N220-, D221-, V222-, S223-, T224-, Q225-, T226-, W227-, E228-, K229-, K230-, S231-, E232-, L233-, D234-, R235-, Y236-, M237-, E238-, M239-, Y240-, P241-, R242-, H243-, R244-, Y245-, G246-, K247-, H248-, S249-, V250-, F251-, K252-, G253-, F254-, S255-, D256-, K257-, V258-, R259-, K260-, N261-, D262-, L263-, D264-, M265-, N266-, V267-, V268-, K269-, E270-, L271-, L272-, S273-, N274-, G275-, A276-, S277-, L278-, T279-, I280-, K281-, D282-, S283-, S284-, N285-, K286-, D287-, P288-, I289-, A290-, V291-, Y292-, F293-, R294-, R295-, T296-, I297-, M298-, N299-, L300-, E301-, M302-, I303-, D304-, I305-, I306-, N307-, K308-, H309-, T310-, T311-, I312-, Y313-, E314-, R315-, R316-, Y317-, I318-, V319-, H320-, S321-, Y322-, L323-, K324-, N325-, Y326-, R327-, N328-, F329-, D330-, Y331-, P332-, F333-, F334-, R335-, K336-, L337-, V338-, L339-, T340-, N341-, K342-, H343-, C344-, L345-, N346-, N347-, Y348-, C349-, N350-, I351-, S352-, D353-, G354-, K355-, Y356-, G357-, T358-, P359-, L360-, H361-, I362-, L363-, A364-, S365-, N366-, K367-, K368-, I369-, I370-, T371-, P372-, N373-, Y374-, M375-, K376-, L377-, L378-, V379-, Y380-, N381-, G382-, N383-, D384-, I385-, N386-, A387-, R388-, G389-, E390-, D391-, T392-, Q393-, M394-, R395-, T396-, P397-, L398-, H399-, K400-, Y401-, L402-, C403-, K404-, F405-, V406-, Y407-, H408-, N409-, I410-, E411-, Y412-, G413-, I414-, R415-, Y416-, Y417-, N418-, E419-, K420-, I421-, I422-, D423-, A424-, F425-, I426-, E427-, L428-, G429-, A430-, D431-, L432-, T433-, I434-, P435-, N436-, D437-, D438-, G439-, M440-, I441-, P442-, V443-, V444-, Y445-, C446-, I447-, H448-, S449-, N450-, A451-, E452-, Y453-, G454-, Y455-, N456-, N457-, I458-, T459-, N460-, I461-, K462-, I463-, I464-, R465-, K466-, L467-, L468-, N469-, L470-, S471-, R472-, H473-, A474-, S475-, H476-, N477-, L478-, F479-, R480-, D481-, R482-, V483-, M484-, H485-, D486-, Y487-, I488-, S489-, N490-, T491-, Y492-, I493-, D494-, L495-, E496-, C497-, L498-, D499-, I500-, I501-, R502-, S503-, L504-, D505-, G506-, Y507-, D508-, I509-, N510-, C511-, Y512-, F513-, E514-, G515-, R516-, T517-, P518-, L519-, H520-, C521-, A522-, I523-, Q524-, Y525-, N526-, F527-, T528-, Q529-, I530-, A531-, E532-, Y533-, L534-, L535-, D536-, R537-, G538-, A539-, D540-, I541-, S542-, L543-, K544-, T545-, D546-, D547-, G548-, K549-, T550-, V551-, F552-, D553-, L554-, S555-, L556-, C557-, S558-, Y559-, I560-, P561-, L562-, K563-, W564-, T565-, S566-, F567-, L568-, I569-, S570-, R571-, L572-, P573-, P574-, K575-, S576-, V577-, I578-, C579-, S580-, L581-, T582-, N583-, H584-, I585-, I586-, D587-, Y588-, V589-, L590-, T591-, N592-, N593-, R594-, R595-, I596-, I597-, W598-, Q599-, S600-, Q601-, M602-, I603-, N604-, K605-, Y606-, V607-, L608-, L609-, L610-, D611-, P612-, S613-, F614-, Y615-, Y616-, R617-, F618-, R619-, N620-, V621-, I622-, E623-, N624-, K625-, L626-, D627-, Q628-, Y629-, N630-, N631-, R632-, Y633-, N634-, M635-, F636-, E637-, H638-, D639-, R640-, D641-, V642-, N643-, E644-, K645-, Y646-, G647-, K648-, V649-, L650-, H651-, D652-, L653-, D654-, T655-, Y656-, I657-, K658-, D659-, V660-, Q661-, V662-, L663-, K664-, S665-, T666-, S667-, I668-, T669-, N670-, N671-, I672-, T673-, L674-, Y675-, D676-, T677-, I678-, I679-, N680-, N681-, K682-, S683-, E684-, F685-, P686-, I687-, R688-, R689-, V690-, N691-, D692-, K693-, Q694-, L695-, I696-, N697-, L698-, I699-, K700-, S701-, N702-, T703-, Y704-, H705-, N706-, L707-, I708-, E709-, K710-, V711-, I712-, K713-, N714-, T715-, L716-, E717-, K718-, Y719-, T720-, L721-, T722-, N723-, I724-, V725-, L726-, E727-, Y728-, M729-, I730-, S731-, S732-, R733-, S734-, Q735-, S736-, S737-, Y738-, L739-, S740-, R741-, I742-, P743-, N744-, E745-, I746-, L747-, L748-, E749-, I750-, L751-, Y752-, K753-, L754-, D755-, M756-, Y757-, D758-, L759-, R760-, N761-, L762-, Y763-, T764-, R765-, Y766-, M767-, R768-, E769-, N770-, D771-, I772-, T773-, E774-, Y775-, H776-, I777-, E778-, N779-, T780-, R781-, S782-, V783-, S784-, T785-, Q786-, T787-, *788-; OPG209: G178X, *191X; OPG210: L733X, L734X, *1881X" - } - } - }, - { - "name": "INMI-Pt2", - "node_attrs": { - "div": 0, - "author": { - "author": "Giombini,E., Gruber,C.E.M., Rueca,M., Gramigna,G., VIta,S., Carletti,F., D'Abramo,A., Lapa,D., Puro,V., Fabeni,L., Butera,O., Colavita,F., Meschi,S., Matusali,G., Specchiarello,E., Vairo,F., Vaia,F., Garbuglia,A.R., Nicastri,E., Antinori,A., GIrardi,E., Maggi,F.", - "value": "Giombini,E., Gruber,C.E.M., Rueca,M., Gramigna,G., VIta,S., Carletti,F., D'Abramo,A., Lapa,D., Puro,V., Fabeni,L., Butera,O., Colavita,F., Meschi,S., Matusali,G., Specchiarello,E., Vairo,F., Vaia,F., Garbuglia,A.R., Nicastri,E., Antinori,A., GIrardi,E., Maggi,F." - }, - "strain_original": { - "value": "INMI-Pt2" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON745215" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Italy" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-19" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A590-", - "T591-", - "-593A", - "-594T", - "-595A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "-196603A" - ] - } - } - }, - { - "name": "MpxV/Spain/MD-HGUGM-66649483/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Buenestado-Serrano,S., Palomino-Cabrera,R., Penas-Utrilla,D., Rodriguez-Grande,J., Sola Campoy,P., Perez-Lago,L., Rodriguez-Grande,C., Herranz Martin,M., Suarez,J., Catalan,P., Munoz,P., Garcia de Viedma,D.", - "value": "Buenestado-Serrano,S., Palomino-Cabrera,R., Penas-Utrilla,D., Rodriguez-Grande,J., Sola Campoy,P., Perez-Lago,L., Rodriguez-Grande,C., Herranz Martin,M., Suarez,J., Catalan,P., Munoz,P., Garcia de Viedma,D." - }, - "strain_original": { - "value": "MpxV/Spain/MD-HGUGM-66649483/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "HGUGM, Microbial Genomics" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON745225" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-27" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G50151A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T" - ], - "OPG069": [ - "D56N" - ] - }, - "labels": { - "aa": "OPG069: D56N" - } - } - }, - { - "name": "INMI-Pt3", - "node_attrs": { - "div": 0, - "author": { - "author": "Rueca,M., Giombini,E., Gruber,C.E.M., Gramigna,G., Mazzotta,V., Carletti,F., Lapa,D., Pittalis,S., Puro,V., Fabeni,L., Butera,O., Colavita,F., Meschi,S., Matusali,G., Specchiarello,E., Vairo,F., Vaia,F., Nicastri,E., Antinori,A., Girardi,E., Maggi,F.", - "value": "Rueca,M., Giombini,E., Gruber,C.E.M., Gramigna,G., Mazzotta,V., Carletti,F., Lapa,D., Pittalis,S., Puro,V., Fabeni,L., Butera,O., Colavita,F., Meschi,S., Matusali,G., Specchiarello,E., Vairo,F., Vaia,F., Nicastri,E., Antinori,A., Girardi,E., Maggi,F." - }, - "strain_original": { - "value": "INMI-Pt3" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON780016" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Italy" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-19" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "-196603A" - ] - } - } - }, - { - "name": "Monkeypox/PT0046/2022", - "node_attrs": { - "div": 2, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0046/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON843174" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-30" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G45851A", - "C136299T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG153": [ - "D457N" - ] - }, - "labels": { - "aa": "OPG153: D457N" - } - } - }, - { - "name": "WA-2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Fletcher,N., Gonzalez,G., Meredith,L., Purves,K., Carr,M., Dean,J., Keogan,B., Crowley,B., Lyons,F., O'Reilly,S., Gautier,V., Mallon,P., Gordon,S., Connell,J., De Gascun,C.F.", - "value": "Fletcher,N., Gonzalez,G., Meredith,L., Purves,K., Carr,M., Dean,J., Keogan,B., Crowley,B., Lyons,F., O'Reilly,S., Gautier,V., Mallon,P., Gordon,S., Connell,J., De Gascun,C.F." - }, - "strain_original": { - "value": "WA-2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University College Dublin, National Virus Reference Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON872184" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Ireland" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-30" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T48785C", - "G49636A", - "C50017T", - "T72809C", - "G178541A", - "A178772-", - "T178773-", - "A178774-", - "T178775-", - "A178776-", - "A178777-", - "C178778-", - "A178779-", - "C178780-", - "G178781-", - "A178782-", - "A178783-", - "T178784-", - "A178785-", - "T178786-", - "G178787-", - "T178788-", - "A178789-" - ], - "OPG068": [ - "G479E" - ], - "OPG069": [ - "T11I" - ], - "OPG092": [ - "K47E" - ] - }, - "labels": { - "aa": "OPG068: G479E; OPG069: T11I; OPG092: K47E" - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3272/2022", - "node_attrs": { - "div": 2, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3272/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880536" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-31" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C61013T", - "C75264T" - ], - "OPG080": [ - "D336N" - ] - }, - "labels": { - "aa": "OPG080: D336N" - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3141/2022", - "node_attrs": { - "div": 0, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3141/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880527" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-27" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/Spain/MD-HGUGM-6642566/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Palomino-Cabrera,R., Penas-Utrilla,D., Buenestado-Serrano,S., Perez-Lago,L., Herranz Martin,M., Veintimilla,C., Catalan,P., Munoz,P., Garcia de Viedma,D.", - "value": "Palomino-Cabrera,R., Penas-Utrilla,D., Buenestado-Serrano,S., Perez-Lago,L., Herranz Martin,M., Veintimilla,C., Catalan,P., Munoz,P., Garcia de Viedma,D." - }, - "strain_original": { - "value": "MpxV/Spain/MD-HGUGM-6642566/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "HGUGM, Microbial Genomics" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON927243" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-21" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T179002-", - "G179003-", - "T179004-", - "A179005-", - "C179006-", - "A179007-", - "C179008-", - "G179009-", - "A179010-", - "T179011-", - "A179012-", - "C179013-", - "C179014-", - "A179015-", - "A179016-", - "T179017-", - "T179018-", - "T179019-", - "C187154T" - ] - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3678/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Chapel,M., Tyler,A., Haidl,E., Domselaar,G.V., Antonation,K., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Jolly,G., Fafard,J., Charest,H., Levade,I.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Chapel,M., Tyler,A., Haidl,E., Domselaar,G.V., Antonation,K., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Jolly,G., Fafard,J., Charest,H., Levade,I." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3678/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP013016" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-13" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G75169A", - "T179052-", - "G179053-", - "A179054-", - "A179055-", - "G179056-", - "T179057-", - "T179058-", - "T179059-", - "A179060-", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-", - "A196604-" - ], - "OPG095": [ - "D123N" - ] - }, - "labels": { - "aa": "OPG095: D123N" - } - } - }, - { - "name": "hMPXV/Austria/MUW1525179/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1525179/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP019275" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Austria" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-10" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "A107070C", - "C144546T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "G190319A", - "-196601A", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "MP03CHUAC", - "node_attrs": { - "div": 2, - "author": { - "author": "Aja-Macaya,P., Rumbo-Feal,S., Poza,M., Canizares,A., Vallejo,J.A., Bou,G.", - "value": "Aja-Macaya,P., Rumbo-Feal,S., Poza,M., Canizares,A., Vallejo,J.A., Bou,G." - }, - "strain_original": { - "value": "MP03CHUAC" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Biomedical research institute (INIBIC), Microbiology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP120938" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C118421T", - "C142607T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG136": [ - "M389I" - ], - "OPG163": [ - "H136Y" - ] - }, - "labels": { - "aa": "OPG136: M389I; OPG163: H136Y" - } - } - }, - { - "name": "hMPXV/Austria/MUW1531848/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1531848/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP133005" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Austria" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-05" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A28524-", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "C188252T", - "A196604-", - "A196605-", - "G197058T", - "C197173G" - ], - "OPG044": [ - "E145X", - "*150X" - ] - }, - "labels": { - "aa": "OPG044: E145X, *150X" - } - } - }, - { - "name": "hMPXV/Austria/MUW1536480/2022", - "node_attrs": { - "div": 2, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1536480/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP133007" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Austria" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-22" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A28524-", - "G32715A", - "G110407A", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "A173189G", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A196604-" - ], - "OPG044": [ - "E145X", - "*150X" - ], - "OPG049": [ - "S146F" - ] - }, - "labels": { - "aa": "OPG044: E145X, *150X; OPG049: S146F" - } - } - }, - { - "name": "MPXV/ITM_pt_07/Belgium/30-May-2022", - "node_attrs": { - "div": 1, - "author": { - "author": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., den Bossche,D.V., Florence,E., Rezende,A.M., Vercauteren,K., Esbroeck,M.V., Bracke,S., Brosius,I., Soentjens,P.", - "value": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., den Bossche,D.V., Florence,E., Rezende,A.M., Vercauteren,K., Esbroeck,M.V., Bracke,S., Brosius,I., Soentjens,P." - }, - "strain_original": { - "value": "MPXV/ITM_pt_07/Belgium/30-May-2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP144216" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-30" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "-133164C", - "A140111-", - "T140112-", - "T140113-", - "A140114-", - "T140115-", - "A140116-", - "A140117-", - "C140118-", - "A140119-", - "A140120-", - "T140121-", - "T140122-", - "A140123-", - "T140124-", - "A140125-", - "A140126-", - "C140127-", - "A140128-", - "A140129-", - "T140130-", - "T140131-", - "A140132-", - "T140133-", - "A140134-", - "A140135-", - "C140136-", - "A140137-", - "A140138-", - "T140139-", - "T140140-", - "A140141-", - "T140142-", - "A140143-", - "A140144-", - "T140145-", - "T140146-", - "G140147-", - "T140148-", - "T140149-", - "T140154A", - "A140155T", - "T168120C", - "A179060-", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-", - "-179092A" - ], - "OPG159": [ - "N115X", - "Y116-", - "N117-", - "N118-", - "Y119-", - "N120-", - "N121-", - "Y122-", - "N123-", - "N124-", - "Y125-", - "N126-", - "C127-", - "Y128X", - "N129K", - "N130Y", - "*146X" - ], - "OPG193": [ - "F263L" - ] - }, - "labels": { - "aa": "OPG159: N115X, Y116-, N117-, N118-, Y119-, N120-, N121-, Y122-, N123-, N124-, Y125-, N126-, C127-, Y128X, N129K, N130Y, *146X; OPG193: F263L" - } - } - }, - { - "name": "hMpxV/Netherlands/NH-AUMC-0001/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Tutu van Furth AM, van der Kuip M, van Els AL, Fievez LC, van Rijckevorsel GG, van den Ouden A, Jonges M, Welkers MR, Welkers,M., Jonges,M.", - "value": "Tutu van Furth AM, van der Kuip M, van Els AL, Fievez LC, van Rijckevorsel GG, van den Ouden A, Jonges M, Welkers MR, Welkers,M., Jonges,M." - }, - "strain_original": { - "value": "hMpxV/Netherlands/NH-AUMC-0001/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP160532" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Netherlands" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A148207T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "G191845A", - "A196604-" - ], - "OPG173": [ - "E57D" - ] - }, - "labels": { - "aa": "OPG173: E57D" - } - } - }, - { - "name": "MPXV_UK_2022_9000107", - "node_attrs": { - "div": 2, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPXV_UK_2022_9000107" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205095" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-13" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C49892T", - "A56110G", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196603A" - ], - "OPG074": [ - "L339S" - ] - }, - "labels": { - "aa": "OPG074: L339S" - } - } - }, - { - "name": "MPX/PT0051/2022", - "node_attrs": { - "div": 0, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "MPX/PT0051/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP245308" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-31" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPX/PT0075/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "MPX/PT0075/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP245329" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-22" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G103240A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-4038/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Griffiths,E., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Griffiths,E., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-4038/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP270028" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-07" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G43708A", - "C133362T", - "G134674A", - "G134755A", - "G148453A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG064": [ - "Q731*" - ], - "OPG174": [ - "R315C" - ] - }, - "labels": { - "aa": "OPG064: Q731*; OPG174: R315C" - } - } - }, - { - "name": "Monkeypox/PT0182/2022", - "node_attrs": { - "div": 0, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0182/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP324497" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-27" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "Monkeypox/PT0188/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0188/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP324502" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-28" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A117044T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "hMpxV/Netherlands/NH-AUMC-0060/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Welkers,M., Jonges,M., de Regt,M., Ooijevaar,R., Wagemakers,A.", - "value": "Welkers,M., Jonges,M., de Regt,M., Ooijevaar,R., Wagemakers,A." - }, - "strain_original": { - "value": "hMpxV/Netherlands/NH-AUMC-0060/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP341487" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Netherlands" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-05" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C96773T", - "C109432T", - "C114985T", - "C142356T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG117": [ - "S242L" - ], - "OPG129": [ - "D525N" - ], - "OPG133": [ - "D238N" - ], - "OPG163": [ - "S52F" - ] - }, - "labels": { - "aa": "OPG117: S242L; OPG129: D525N; OPG133: D238N; OPG163: S52F" - } - } - }, - { - "name": "hMPXV-IHU00001", - "node_attrs": { - "div": 1, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "strain_original": { - "value": "hMPXV-IHU00001" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP382478" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-13" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C178006T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG205": [ - "S784F" - ] - }, - "labels": { - "aa": "OPG205: S784F" - } - } - }, - { - "name": "Monkeypox/PT0333/2022", - "node_attrs": { - "div": 0, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0333/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP414364" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-27" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPX_96X1Vd_9000218", - "node_attrs": { - "div": 0, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_96X1Vd_9000218" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415196" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-03-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPX_1bN2W6_9000321", - "node_attrs": { - "div": 1, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_1bN2W6_9000321" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415261" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C10641T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG022": [ - "G73D" - ] - }, - "labels": { - "aa": "OPG022: G73D" - } - } - }, - { - "name": "hMPXV-CH-38212023/2022", - "node_attrs": { - "div": 0, - "author": { - "author": "Laubscher,F., Chudzinsk,V., Cordey,S., Schibler,M., Kaiser,L., Renzoni,A.", - "value": "Laubscher,F., Chudzinsk,V., Cordey,S., Schibler,M., Kaiser,L., Renzoni,A." - }, - "strain_original": { - "value": "hMPXV-CH-38212023/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University Hospitals of Geneva, Laboratory of Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP422245" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Switzerland" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-30" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G178922-", - "G178923-", - "A178924-", - "A178925-", - "C178926-", - "A178927-", - "T178928-", - "A178929-", - "T178930-", - "A178931-", - "T178932-", - "T178933-", - "T178934-", - "A178935-", - "G178936-", - "A178937-", - "A178938-", - "A178939-" - ] - } - } - }, - { - "name": "hMPXV/Austria/MUW1540386/2022", - "node_attrs": { - "div": 2, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1540386/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP422343" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Austria" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-08" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C102355T", - "C113923T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG121": [ - "S189L" - ], - "OPG133": [ - "D592N" - ] - }, - "labels": { - "aa": "OPG121: S189L; OPG133: D592N" - } - } - }, - { - "name": "hMPXV/Austria/MUW1539124/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1539124/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP422342" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Austria" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-02" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G28490A", - "G102694A", - "C110960T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG044": [ - "D134N" - ] - }, - "labels": { - "aa": "OPG044: D134N" - } - } - }, - { - "name": "MPXV-USA-IL-IDPH-061", - "node_attrs": { - "div": 1, - "author": { - "author": "Gagnon,K.T.", - "value": "Gagnon,K.T." - }, - "strain_original": { - "value": "MPXV-USA-IL-IDPH-061" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536722" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-24" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "C156533T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196601A", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "9000451", - "node_attrs": { - "div": 3, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "9000451" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536813" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "-595T", - "G61102A", - "C77309T", - "C96440T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196602A", - "-196603A" - ], - "OPG080": [ - "S306F" - ], - "OPG098": [ - "S137L" - ], - "OPG117": [ - "T131I" - ] - }, - "labels": { - "aa": "OPG080: S306F; OPG098: S137L; OPG117: T131I" - } - } - }, - { - "name": "Monkeypox/PT0447/2022", - "node_attrs": { - "div": 2, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0447/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555528" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-04" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C92352T", - "C132698T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "Monkeypox/PT0591/2022", - "node_attrs": { - "div": 2, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0591/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555658" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-13" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A136513-", - "T136514-", - "C136515-", - "C136572T", - "C138333T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G158190A" - ], - "OPG153": [ - "E366K", - "D385-" - ] - }, - "labels": { - "aa": "OPG153: E366K, D385-" - } - } - }, - { - "name": "MPXV/Human/USA/CA-CDPH-MPX000038/2022", - "node_attrs": { - "div": 2, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-CDPH-MPX000038/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP587260" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-11" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C42708T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "C179541T" - ] - } - } - }, - { - "name": "Slovenia-MPXV-24-2022", - "node_attrs": { - "div": 2, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "strain_original": { - "value": "Slovenia-MPXV-24-2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605566" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594A", - "-595T", - "C167944T", - "C180273A", - "T196367-", - "G196368-", - "T196369-" - ], - "OPG001": [ - "C245-" - ], - "OPG193": [ - "S204L" - ], - "OPG208": [ - "F336L" - ] - }, - "labels": { - "aa": "OPG001: C245-; OPG193: S204L; OPG208: F336L" - } - } - }, - { - "name": "Slovenia-MPXV-33-2022", - "node_attrs": { - "div": 0, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "strain_original": { - "value": "Slovenia-MPXV-33-2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605575" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A" - ] - } - } - }, - { - "name": "Slovenia-MPXV-39-2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "strain_original": { - "value": "Slovenia-MPXV-39-2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605580" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G189288A" - ] - } - } - }, - { - "name": "Slovenia-MPXV-41-2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "strain_original": { - "value": "Slovenia-MPXV-41-2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605582" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C126-", - "-595T", - "C27187T" - ], - "OPG043": [ - "D257N" - ] - }, - "labels": { - "aa": "OPG043: D257N" - } - } - }, - { - "name": "Monkeypox virus/Human/USA/CA-LACPHL-MA00222/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "Monkeypox virus/Human/USA/CA-LACPHL-MA00222/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP680500" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-03" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C6310T", - "A39081T", - "C81194T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "G190900A" - ], - "NBT03_gp174": [ - "R164K" - ], - "OPG057": [ - "I372N" - ] - }, - "labels": { - "aa": "NBT03_gp174: R164K; OPG057: I372N" - } - } - }, - { - "name": "ANT_INS_MPX_0039_L", - "node_attrs": { - "div": 2, - "author": { - "author": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M.", - "value": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M." - }, - "strain_original": { - "value": "ANT_INS_MPX_0039_L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP693649" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-29" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A267-", - "T268-", - "G269-", - "G127058A", - "G136194A", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG148": [ - "R358K" - ], - "OPG153": [ - "H492Y" - ] - }, - "labels": { - "aa": "OPG148: R358K; OPG153: H492Y" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI547", - "node_attrs": { - "div": 1, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI547" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP715827" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G92288C", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG113": [ - "R186S" - ] - }, - "labels": { - "aa": "OPG113: R186S" - } - } - }, - { - "name": "MPXV_USA_2022_OR0004", - "node_attrs": { - "div": 3, - "author": { - "author": "Gigante,C.M., Cogswell,K., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Morrison,S.S., Desch,M., Knipe,K., Weigand,M.R., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Grenz,L., Li,Y.", - "value": "Gigante,C.M., Cogswell,K., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Morrison,S.S., Desch,M., Knipe,K., Weigand,M.R., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Grenz,L., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_OR0004" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP752115" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G53484A", - "C97153T", - "A173274-", - "T173275-", - "G184980A" - ], - "OPG071": [ - "H319Y" - ], - "OPG210": [ - "E1209K" - ] - }, - "labels": { - "aa": "OPG071: H319Y; OPG210: E1209K" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI571", - "node_attrs": { - "div": 1, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI571" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP764629" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G21655A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG037": [ - "S260L" - ] - }, - "labels": { - "aa": "OPG037: S260L" - } - } - }, - { - "name": "VAC_INS_MPX_0952_C", - "node_attrs": { - "div": 6, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "strain_original": { - "value": "VAC_INS_MPX_0952_C" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP819948" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-15" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C33082T", - "C36405T", - "C40849T", - "G68103A", - "G117233A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "C180361T" - ], - "OPG049": [ - "D24N" - ], - "OPG055": [ - "A227T" - ], - "OPG060": [ - "E112K" - ] - }, - "labels": { - "aa": "OPG049: D24N; OPG055: A227T; OPG060: E112K" - } - } - }, - { - "name": "DC_INS_MPX_1011_L", - "node_attrs": { - "div": 4, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "strain_original": { - "value": "DC_INS_MPX_1011_L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP837478" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-20" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G16956A", - "C94427T", - "G141759A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "C184829T" - ], - "OPG114": [ - "E81K" - ] - }, - "labels": { - "aa": "OPG114: E81K" - } - } - }, - { - "name": "NJ-MPXV-007-rpt1", - "node_attrs": { - "div": 1, - "author": { - "author": "Palmateer,N.C.", - "value": "Palmateer,N.C." - }, - "strain_original": { - "value": "NJ-MPXV-007-rpt1" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "New Jersey Department of Health, Public Health and Environmental Laboratories" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP879728" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-05" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "C178702T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00284/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00284/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP890542" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-28" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "C189710T" - ] - } - } - }, - { - "name": "hMPXV-CH-38292866/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Laubscher,F., Chudzinsk,V., Schibler,M., Kaiser,L., Renzoni,A.", - "value": "Laubscher,F., Chudzinsk,V., Schibler,M., Kaiser,L., Renzoni,A." - }, - "strain_original": { - "value": "hMPXV-CH-38292866/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University Hospitals of Geneva, Laboratory of Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ411312" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Switzerland" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-08" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C87764T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG109": [ - "E562K" - ] - }, - "labels": { - "aa": "OPG109: E562K" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI711", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI711" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ451896" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "A87268G", - "G115865A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG109": [ - "V727A" - ], - "OPG134": [ - "R39K" - ] - }, - "labels": { - "aa": "OPG109: V727A; OPG134: R39K" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI717", - "node_attrs": { - "div": 6, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI717" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ451902" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C3602T", - "C53342T", - "C124495T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G159789A", - "C170573T", - "G190695A", - "G193608A" - ], - "NBT03_gp174": [ - "E96K" - ], - "OPG003": [ - "E336K" - ], - "OPG071": [ - "R366K" - ], - "OPG198": [ - "S179L" - ] - }, - "labels": { - "aa": "NBT03_gp174: E96K; OPG003: E336K; OPG071: R366K; OPG198: S179L" - } - } - }, - { - "name": "NY-NYCPHL-000684", - "node_attrs": { - "div": 2, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000684" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468746" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-18" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C100867T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150566A", - "-150567T", - "G158573A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG119": [ - "S161L" - ], - "OPG120": [ - "M294I" - ] - }, - "labels": { - "aa": "OPG119: S161L; OPG120: M294I" - } - } - }, - { - "name": "NY-NYCPHL-000739", - "node_attrs": { - "div": 3, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000739" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468776" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-13" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A10432-", - "T10433-", - "T10434-", - "A10435-", - "G10436-", - "C13171T", - "G23067-", - "T23068-", - "A23069-", - "A23070-", - "T23071-", - "C23072-", - "T23073-", - "T23074-", - "G23075-", - "T23076-", - "C23077-", - "G23078-", - "A23079-", - "T23080-", - "G23081-", - "A23082-", - "G23083-", - "G23084-", - "A23085-", - "C23086-", - "A23087-", - "T23088-", - "A23089-", - "T23090-", - "A23091-", - "C39547T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "G152728A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG024": [ - "D20N" - ], - "OPG038": [ - "T23X", - "I24-", - "C25-", - "P26-", - "H27-", - "R28-", - "Q29-", - "D30-", - "Y31-", - "*221X" - ], - "OPG057": [ - "D217N" - ], - "OPG180": [ - "D13N" - ] - }, - "labels": { - "aa": "OPG024: D20N; OPG038: T23X, I24-, C25-, P26-, H27-, R28-, Q29-, D30-, Y31-, *221X; OPG057: D217N; OPG180: D13N" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00406/2023", - "node_attrs": { - "div": 6, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00406/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503829" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-01-09" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G2146A", - "C2749T", - "C39044T", - "G112552A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "C167231T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "T187876C", - "G194461A", - "C195064T" - ], - "OPG002": [ - "M1I" - ], - "OPG132": [ - "S330L" - ] - }, - "labels": { - "aa": "OPG002: M1I; OPG132: S330L" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI749", - "node_attrs": { - "div": 0, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI749" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ547776" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "hMpxV/USA/CACDPH1MPX1000162/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J." - }, - "strain_original": { - "value": "hMpxV/USA/CACDPH1MPX1000162/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ547889" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-23" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T6975-", - "G145790A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - }, - { - "name": "hMpxV/USA/CACDPH1MPX1000174/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J." - }, - "strain_original": { - "value": "hMpxV/USA/CACDPH1MPX1000174/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ547882" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-12-23" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C565-", - "A566-", - "T567-", - "C3850T", - "T6975-", - "T39315A", - "C132440T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "G193360A", - "G196581-", - "T196582-", - "C196583-" - ], - "OPG003": [ - "R253Q" - ], - "OPG057": [ - "D294V" - ] - }, - "labels": { - "aa": "OPG003: R253Q; OPG057: D294V" - } - } - }, - { - "name": "INMI-22872022", - "node_attrs": { - "div": 2, - "author": { - "author": "Rueca,M., Tucci,F.G., Mazzotta,V., Gramigna,G., Gruber,C.E.M., Fabeni,L., Giombini,E., Matusali,G., Pinnetti,C., Mariano,A., Butera,O., Specchiarello,E., Mondi,A., Lanini,S., Carletti,F., Girardi,E., Vaia,F., Nicastri,E., Antinori,A., Maggi,F.", - "value": "Rueca,M., Tucci,F.G., Mazzotta,V., Gramigna,G., Gruber,C.E.M., Fabeni,L., Giombini,E., Matusali,G., Pinnetti,C., Mariano,A., Butera,O., Specchiarello,E., Mondi,A., Lanini,S., Carletti,F., Girardi,E., Vaia,F., Nicastri,E., Antinori,A., Maggi,F." - }, - "strain_original": { - "value": "INMI-22872022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute for Infectious Diseases \"L. Spallanzani\" - IRCCS, Laboratory of Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ570421" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Italy" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-22" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C106275T", - "G111562A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T" - ], - "OPG130": [ - "S114F" - ] - }, - "labels": { - "aa": "OPG130: S114F" - } - } - }, - { - "name": "MPXV/Spain/HUNSC_ITER_0006b/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Munoz-Barrera,A., Ciuffreda,L., Alcoba-Florez,J., Rubio-Rodriguez,L.A., Rodriguez-Perez,H., Gil-Campesino,H., Garcia-Martinez de Artola,D., Salas-Hernandez,J., Rodriguez-Nunez,J., Inigo-Campos,A., Garcia-Olivares,V., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C.", - "value": "Munoz-Barrera,A., Ciuffreda,L., Alcoba-Florez,J., Rubio-Rodriguez,L.A., Rodriguez-Perez,H., Gil-Campesino,H., Garcia-Martinez de Artola,D., Salas-Hernandez,J., Rodriguez-Nunez,J., Inigo-Campos,A., Garcia-Olivares,V., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C." - }, - "strain_original": { - "value": "MPXV/Spain/HUNSC_ITER_0006b/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ581848" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-01" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-133169T", - "-133170T", - "-133171T", - "-133172C", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C174264T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T" - ] - } - } - }, - { - "name": "MPXV/Spain/HUNSC_ITER_0007b/2022", - "node_attrs": { - "div": 2, - "author": { - "author": "Munoz-Barrera,A., Ciuffreda,L., Alcoba-Florez,J., Rubio-Rodriguez,L.A., Rodriguez-Perez,H., Gil-Campesino,H., Garcia-Martinez de Artola,D., Salas-Hernandez,J., Rodriguez-Nunez,J., Inigo-Campos,A., Garcia-Olivares,V., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C.", - "value": "Munoz-Barrera,A., Ciuffreda,L., Alcoba-Florez,J., Rubio-Rodriguez,L.A., Rodriguez-Perez,H., Gil-Campesino,H., Garcia-Martinez de Artola,D., Salas-Hernandez,J., Rodriguez-Nunez,J., Inigo-Campos,A., Garcia-Olivares,V., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C." - }, - "strain_original": { - "value": "MPXV/Spain/HUNSC_ITER_0007b/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ581849" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-05" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A52777C", - "C150418T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T169409C", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C" - ], - "OPG071": [ - "Y554*" - ] - }, - "labels": { - "aa": "OPG071: Y554*" - } - } - }, - { - "name": "MPXV/human/Taiwan/110-093354/2023", - "node_attrs": { - "div": 8, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "strain_original": { - "value": "MPXV/human/Taiwan/110-093354/2023" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ672580" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Taiwan" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-03-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C39503G", - "G43620A", - "A44076G", - "G45563A", - "T69121C", - "T80764C", - "A130204G", - "A143123G", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG057": [ - "K231N" - ], - "OPG064": [ - "F608S" - ], - "OPG087": [ - "Y89H" - ], - "OPG104": [ - "N86D" - ], - "OPG164": [ - "T116A" - ] - }, - "labels": { - "aa": "OPG057: K231N; OPG064: F608S; OPG087: Y89H; OPG104: N86D; OPG164: T116A" - } - } - }, - { - "name": "MPXV/human/Taiwan/110-122438/2023", - "node_attrs": { - "div": 3, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "strain_original": { - "value": "MPXV/human/Taiwan/110-122438/2023" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ721951" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Taiwan" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-03-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "T133084-", - "T133085-", - "T133086-", - "T133087-", - "T133088-", - "T149983A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G160358A", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A184479G", - "G193496T", - "A193498T", - "A193748G", - "T194019G", - "T194021A", - "G194086A" - ], - "OPG003": [ - "K298N", - "E299V", - "C473G", - "R495K" - ], - "OPG176": [ - "S59T" - ], - "OPG210": [ - "R1042G" - ] - }, - "labels": { - "aa": "OPG003: K298N, E299V, C473G, R495K; OPG176: S59T; OPG210: R1042G" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI882", - "node_attrs": { - "div": 1, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI882" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773501" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C81716T", - "G150550-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G" - ] - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00485/2023", - "node_attrs": { - "div": 6, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00485/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ918696" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-03-11" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G30285A", - "G37487A", - "C71193T", - "G119839A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C161690T", - "C177865T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ], - "OPG047": [ - "P304S" - ], - "OPG137": [ - "E80K" - ], - "OPG188": [ - "S32F" - ], - "OPG205": [ - "S737F" - ] - }, - "labels": { - "aa": "OPG047: P304S; OPG137: E80K; OPG188: S32F; OPG205: S737F" - } - } - }, - { - "name": "MPXV/UZ_REGA_37", - "node_attrs": { - "div": 1, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_37" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035643" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-30" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G50982A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G150577-", - "A150578-", - "T150579-", - "A150580-", - "T150581-", - "G150582-", - "A150583-", - "T150584-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_74", - "node_attrs": { - "div": 1, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_74" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035680" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-03" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A40037G", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_75", - "node_attrs": { - "div": 0, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_75" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035681" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-03" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "T149487-", - "A149488-", - "C149489-", - "G149490-", - "T149491-", - "T149492-", - "G149493-", - "A149494-", - "A149495-", - "C149496-", - "A149497-", - "A149498-", - "G149499-", - "T149500-", - "C149501-", - "C149502-", - "A149503-" - ], - "OPG175": [ - "Y16-", - "V17-", - "E18-", - "Q19-", - "V20-", - "H21X", - "*126X" - ] - }, - "labels": { - "aa": "OPG175: Y16-, V17-, E18-, Q19-, V20-, H21X, *126X" - } - } - }, - { - "name": "MPXV/UZ_REGA_87", - "node_attrs": { - "div": 0, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_87" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035693" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-09" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_89", - "node_attrs": { - "div": 0, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_89" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035695" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-09" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_91", - "node_attrs": { - "div": 0, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_91" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035697" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-15" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_92", - "node_attrs": { - "div": 0, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_92" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035698" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-27" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_93", - "node_attrs": { - "div": 1, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_93" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035699" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-30" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C10015A", - "T155417-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_125", - "node_attrs": { - "div": 3, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_125" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035731" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-20" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G61361A", - "C110147T", - "G162623A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG188": [ - "R343K" - ] - }, - "labels": { - "aa": "OPG188: R343K" - } - } - }, - { - "name": "MPXV/UZ_REGA_123", - "node_attrs": { - "div": 2, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_123" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035729" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-20" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C19277T", - "C166803T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG192": [ - "P25S" - ] - }, - "labels": { - "aa": "OPG192: P25S" - } - } - }, - { - "name": "MPXV/UZ_REGA_161/Belgium/2022", - "node_attrs": { - "div": 0, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_161/Belgium/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR086970" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-27" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "T195509-", - "A195510-", - "A195511-" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_216/Belgium/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_216/Belgium/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR095034" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-08" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C98294T", - "C118161T", - "T133078-", - "G161458A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG117": [ - "S749F" - ], - "OPG136": [ - "R476Q" - ] - }, - "labels": { - "aa": "OPG117: S749F; OPG136: R476Q" - } - } - }, - { - "name": "RNA", - "node_attrs": { - "div": 1, - "strain_original": { - "value": "RNA" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OX291435" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovakia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-25" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G57076A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A164529-", - "C164530-", - "C164531-", - "A164532-", - "T164533-", - "C164534-", - "T164535-", - "T164536-", - "T164537-", - "G164538-", - "A164539-", - "A164540-", - "A164541-", - "A164542-", - "T164543-", - "T164544-", - "A164545-", - "T164546-", - "G164547-", - "A164548-", - "T164549-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A196604-" - ], - "OPG074": [ - "S17L" - ], - "OPG189": [ - "R399X", - "P400-", - "S401-", - "L402-", - "K403-", - "I404-", - "M405-", - "I406X", - "*562X" - ] - }, - "labels": { - "aa": "OPG074: S17L; OPG189: R399X, P400-, S401-, L402-, K403-, I404-, M405-, I406X, *562X" - } - } - }, - { - "name": "RNA", - "node_attrs": { - "div": 0, - "strain_original": { - "value": "RNA" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OX261748" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovakia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-13" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A196604-" - ] - } - } - }, - { - "name": "RNA", - "node_attrs": { - "div": 1, - "strain_original": { - "value": "RNA" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OX297403" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovakia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-09" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G64522A", - "T133078-", - "T133079-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A196604-" - ] - } - } - }, - { - "name": "NODE_0000018", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G169928A" - ], - "OPG197": [ - "D87N" - ] - }, - "labels": { - "aa": "OPG197: D87N" - } - }, - "children": [ - { - "name": "Monkeypox/BR0001/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Claro,I.M., de Lima,E.L., Romano,C.M., Candido,D.S., Lindoso,J.A.L., Barra,L.A.C., Borges,L.M.S., Medeiros,L.A., Tomishige,M.Y.S., Ramundo,M.S., Moutinho,T., da Silva,A.J.D., Rodrigues,C.C.M., de Azevedo,L.C.F., Villas-Boas,L.S., da Silva,C.A.M., Coletti,T.M., O'Toole,A., Quick,J., Loman,N., Rambaut,A., Faria,N.R., Figueiredo-Mello,C., Sabino,E.C.", - "value": "Claro,I.M., de Lima,E.L., Romano,C.M., Candido,D.S., Lindoso,J.A.L., Barra,L.A.C., Borges,L.M.S., Medeiros,L.A., Tomishige,M.Y.S., Ramundo,M.S., Moutinho,T., da Silva,A.J.D., Rodrigues,C.C.M., de Azevedo,L.C.F., Villas-Boas,L.S., da Silva,C.A.M., Coletti,T.M., O'Toole,A., Quick,J., Loman,N., Rambaut,A., Faria,N.R., Figueiredo-Mello,C., Sabino,E.C." - }, - "strain_original": { - "value": "Monkeypox/BR0001/2022" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Imperial College London, School of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON751962" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Brazil" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-07" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T591-", - "A592-", - "-594T", - "G10118A", - "C15004T", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "T172973-", - "A172974-", - "T172975-", - "A172976-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-" - ], - "OPG021": [ - "E178K" - ] - }, - "labels": { - "aa": "OPG021: E178K" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI811", - "node_attrs": { - "div": 5, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI811" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773430" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C23345T", - "C23353T", - "C23356T", - "G58518A", - "G150550-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG039": [ - "D255N", - "D256N" - ] - }, - "labels": { - "aa": "OPG039: D255N, D256N" - } - } - } - ] - }, - { - "name": "NODE_0000019", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C65571T", - "G144988A", - "C156429T" - ] - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-3607/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Chapel,M., Tyler,A., Haidl,E., Domselaar,G.V., Antonation,K., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Jolly,G., Fafard,J., Charest,H., Levade,I.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Chapel,M., Tyler,A., Haidl,E., Domselaar,G.V., Antonation,K., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Jolly,G., Fafard,J., Charest,H., Levade,I." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3607/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP013010" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-09" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/CAN/UN-NML-4014/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Griffiths,E., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Griffiths,E., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-4014/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP270025" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-05" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C45103T", - "G74933A", - "G131867A" - ], - "OPG064": [ - "E266K" - ], - "OPG095": [ - "R44Q" - ], - "OPG151": [ - "E982K" - ] - }, - "labels": { - "aa": "OPG064: E266K; OPG095: R44Q; OPG151: E982K" - } - } - } - ] - }, - { - "name": "NODE_0000020", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C130606T" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI276", - "node_attrs": { - "div": 1, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI276" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP263631" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "INMI-18982022", - "node_attrs": { - "div": 3, - "author": { - "author": "Rueca,M., Tucci,F.G., Mazzotta,V., Gramigna,G., Gruber,C.E.M., Fabeni,L., Giombini,E., Matusali,G., Pinnetti,C., Mariano,A., Butera,O., Specchiarello,E., Mondi,A., Lanini,S., Carletti,F., Girardi,E., Vaia,F., Nicastri,E., Antinori,A., Maggi,F.", - "value": "Rueca,M., Tucci,F.G., Mazzotta,V., Gramigna,G., Gruber,C.E.M., Fabeni,L., Giombini,E., Matusali,G., Pinnetti,C., Mariano,A., Butera,O., Specchiarello,E., Mondi,A., Lanini,S., Carletti,F., Girardi,E., Vaia,F., Nicastri,E., Antinori,A., Maggi,F." - }, - "strain_original": { - "value": "INMI-18982022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute for Infectious Diseases \"L. Spallanzani\" - IRCCS, Laboratory of Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ627927" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Italy" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-16" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C45203T", - "C88917T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - } - ] - }, - { - "name": "NODE_0000021", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G141131A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - }, - "children": [ - { - "name": "Monkeypox/PT0544/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0544/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555615" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-25" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C54268T", - "G109514A", - "C182968T", - "-196603A" - ], - "OPG210": [ - "S538L" - ] - }, - "labels": { - "aa": "OPG210: S538L" - } - } - }, - { - "name": "RNA", - "node_attrs": { - "div": 5, - "strain_original": { - "value": "RNA" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OX291694" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovakia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-01" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C15311T", - "C28887T", - "C54262T", - "G81015T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A196604-" - ], - "OPG045": [ - "E126K" - ], - "OPG104": [ - "T2K" - ] - }, - "labels": { - "aa": "OPG045: E126K; OPG104: T2K" - } - } - } - ] - }, - { - "name": "NODE_0000022", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C12684T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ], - "OPG023": [ - "E73K" - ] - }, - "labels": { - "aa": "OPG023: E73K" - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00298/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00298/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP890532" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-30" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C33291T", - "C135135T" - ], - "OPG050": [ - "D40N" - ] - }, - "labels": { - "aa": "OPG050: D40N" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00481/2023", - "node_attrs": { - "div": 3, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00481/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ644787" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-01-18" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G90825A", - "G102694A" - ] - } - } - } - ] - }, - { - "name": "NODE_0000023", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C156205T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00357/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00357/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP920695" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-08" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A469-", - "A470-", - "G471-", - "G23685A", - "C33499T", - "A196604-" - ], - "OPG039": [ - "S145F" - ], - "OPG051": [ - "E51K" - ] - }, - "labels": { - "aa": "OPG039: S145F; OPG051: E51K" - } - } - }, - { - "name": "Monkeypox virus/Human/USA/CA-LACPHL-MA00395/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "Monkeypox virus/Human/USA/CA-LACPHL-MA00395/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ330974" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-12-23" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000024", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G106113A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "C189810T" - ] - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00475/2022", - "node_attrs": { - "div": 8, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00475/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ644781" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-22" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G13224A", - "C22664T", - "C23353T", - "G24446A", - "G25294A", - "C25308T", - "T179174-", - "T179175-" - ], - "OPG024": [ - "S2L" - ], - "OPG038": [ - "D166N" - ], - "OPG039": [ - "D256N" - ], - "OPG040": [ - "S62L", - "P345S" - ] - }, - "labels": { - "aa": "OPG024: S2L; OPG038: D166N; OPG039: D256N; OPG040: S62L, P345S" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00489/2023", - "node_attrs": { - "div": 5, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00489/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ918700" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-02-20" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G66587A", - "G143857A", - "C144237T" - ], - "OPG165": [ - "S241L" - ] - }, - "labels": { - "aa": "OPG165: S241L" - } - } - } - ] - }, - { - "name": "NODE_0000025", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C141757T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - }, - "children": [ - { - "name": "HRYC_MPXV001", - "node_attrs": { - "div": 5, - "author": { - "author": "Ponce-Alonso,M., Martinez-Garcia,L., Olavarrieta,L., Galan,J.C.", - "value": "Ponce-Alonso,M., Martinez-Garcia,L., Olavarrieta,L., Galan,J.C." - }, - "strain_original": { - "value": "HRYC_MPXV001" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Hospital Ramon y Cajal, Microbiology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR126131" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-21" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C11747-", - "C34432T", - "C48324T", - "G101294A", - "G190695A" - ], - "NBT03_gp174": [ - "E96K" - ], - "OPG023": [ - "G385X", - "*661X" - ], - "OPG053": [ - "E87K" - ], - "OPG120": [ - "S152L" - ] - }, - "labels": { - "aa": "NBT03_gp174: E96K; OPG023: G385X, *661X; OPG053: E87K; OPG120: S152L" - } - } - }, - { - "name": "NODE_0000026", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.18" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C43706T", - "T124690C" - ] - }, - "labels": { - "clade": "B.1.18" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-083401/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-083401/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP628451" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.18" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000027", - "node_attrs": { - "div": 5, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.18" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G67758A", - "C170049T" - ] - } - }, - "children": [ - { - "name": "VAC_INS_MPX_1052_E", - "node_attrs": { - "div": 5, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "strain_original": { - "value": "VAC_INS_MPX_1052_E" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP837471" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-25" - }, - "lineage": { - "value": "B.1.18" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "LBMB-UTP_MP-025_VAC", - "node_attrs": { - "div": 9, - "author": { - "author": "Lopez,P.A., Orjuela,M., Tabares,F.A., Anacona,J.D., Zuluaga-Velez,A., Sepulveda-Arias,J.C.", - "value": "Lopez,P.A., Orjuela,M., Tabares,F.A., Anacona,J.D., Zuluaga-Velez,A., Sepulveda-Arias,J.C." - }, - "strain_original": { - "value": "LBMB-UTP_MP-025_VAC" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ148474" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-15" - }, - "lineage": { - "value": "B.1.18" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C128242T", - "G144572A", - "C166940T", - "C168829T" - ], - "OPG150": [ - "S155F" - ] - }, - "labels": { - "aa": "OPG150: S155F" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000028", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C148268T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - }, - "children": [ - { - "name": "MPXV_IRBA22-11", - "node_attrs": { - "div": 1, - "author": { - "author": "Jarjaval,F., Nolent,F., Criqui,A., Chapus,C., Lamer,O., Ferraris,O., Gorge,O.", - "value": "Jarjaval,F., Nolent,F., Criqui,A., Chapus,C., Lamer,O., Ferraris,O., Gorge,O." - }, - "strain_original": { - "value": "MPXV_IRBA22-11" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IRBA, D.DNRBC/D.2MI/U.BACT" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON755039" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-19" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-" - ] - } - } - }, - { - "name": "NODE_0000029", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.19" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G9963A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG021": [ - "R126K" - ] - }, - "labels": { - "aa": "OPG021: R126K", - "clade": "B.1.19" - } - }, - "children": [ - { - "name": "9000405", - "node_attrs": { - "div": 4, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "9000405" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536781" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.19" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C62868T", - "C74417T", - "A196604-" - ], - "OPG094": [ - "S213L" - ] - }, - "labels": { - "aa": "OPG094: S213L" - } - } - }, - { - "name": "ID6821", - "node_attrs": { - "div": 2, - "author": { - "author": "Viscardi,M., Cozzolino,L., De Martinis,C., Cardillo,L., Fusco,G.", - "value": "Viscardi,M., Cozzolino,L., De Martinis,C., Cardillo,L., Fusco,G." - }, - "strain_original": { - "value": "ID6821" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Istituto Zooprofilattico Sperimentale del Mezzogiorno, Hanimal Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP838893" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Italy" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-21" - }, - "lineage": { - "value": "B.1.19" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A4728-", - "A4729-", - "C4730-", - "T4731-", - "A4732-", - "A4733-", - "C4734-", - "T4735-", - "T4736-", - "A4737-", - "T4738-", - "G4739-", - "T133100-", - "T133101-", - "T133102-", - "C133103-", - "G133104-", - "A133105-", - "A133106-", - "T133107-", - "T133108-", - "C133109-", - "A133110-", - "C133111-", - "G133112-", - "A140105-", - "T140106-", - "A140107-", - "A140108-", - "C140109-", - "A140110-", - "A140111-", - "T140112-", - "T140113-", - "A157667-", - "A157668-", - "T157669-", - "C157670-", - "A157671-", - "A157672-", - "T157673-", - "G157674-", - "A157675-", - "T157676-", - "A157677-", - "A157678-", - "A157679-", - "A157680-", - "A157681-", - "T157682-", - "T157683-", - "T157684-", - "T157685-", - "T163214-", - "C163215-", - "T163216-", - "T163217-", - "A163218-", - "T163219-", - "A163220-", - "T163221-", - "A163408-", - "A163409-", - "T163410-", - "T163411-", - "C163412-", - "T163413-", - "T163414-", - "C163415-", - "C163416-", - "G174519-", - "A174520-", - "T174521-", - "G174522-", - "A174523-", - "A174524-", - "G174525-", - "A174526-", - "T174527-", - "G174528-", - "A174529-", - "A174530-", - "A180469-", - "A180470-", - "A180471-", - "A180472-", - "A180473-", - "A180474-", - "T180475-", - "T180476-", - "T181102-", - "A181103-", - "T181104-", - "A181105-", - "T181106-", - "T181107-", - "C181108-", - "C181109-", - "T181110-", - "T192477-", - "T192478-", - "A192479-", - "G192480-", - "T192481-", - "T192482-", - "A192483-", - "A192484-", - "G192485-", - "T192486-", - "C192487-", - "A192488-" - ], - "OPG159": [ - "N113X", - "N114-", - "N115-", - "Y116X", - "*146X" - ], - "OPG189": [ - "N26-", - "S27-", - "S28-" - ] - }, - "labels": { - "aa": "OPG159: N113X, N114-, N115-, Y116X, *146X; OPG189: N26-, S27-, S28-" - } - } - }, - { - "name": "NODE_0000030", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.19" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150003A", - "A179077-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "A179140-", - "A179142-", - "A179144-", - "C179145-", - "A179146-" - ] - } - }, - "children": [ - { - "name": "Monkeypox/PT0572/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0572/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555643" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-05" - }, - "lineage": { - "value": "B.1.19" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C55057T", - "A169944T", - "T179078-", - "T179138-", - "T179139-", - "T179141-", - "T179143-", - "T179147-", - "T179148-", - "C185326T", - "-196603A" - ], - "NBT03_gp052": [ - "E29K" - ], - "OPG197": [ - "E92V" - ], - "OPG210": [ - "S1324L" - ] - }, - "labels": { - "aa": "NBT03_gp052: E29K; OPG197: E92V; OPG210: S1324L" - } - } - }, - { - "name": "MPXV-1047", - "node_attrs": { - "div": 7, - "author": { - "author": "Zeggagh,J., Ferraris,O., Salmona,M., Tarantola,A., Molina,J.M., Delaugerre,C.", - "value": "Zeggagh,J., Ferraris,O., Salmona,M., Tarantola,A., Molina,J.M., Delaugerre,C." - }, - "strain_original": { - "value": "MPXV-1047" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Hopital Saint Louis, Paris" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ172215" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-07" - }, - "lineage": { - "value": "B.1.19" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A2591G", - "A31053G", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "T133084-", - "-133164C", - "-133165A", - "-133166A", - "-133167T", - "-133168C", - "-133169T", - "-133173T", - "T133633-", - "G150577-", - "A150578-", - "T150579-", - "A150580-", - "T150581-", - "G150582-", - "A150583-", - "T150584-", - "G150620-", - "G150621-", - "A150622-", - "T150623-", - "A150624-", - "T150625-", - "G150626-", - "A150627-", - "T150628-", - "A150629-", - "A152668-", - "T152680-", - "T155897A", - "C173533A", - "-179077T", - "-179140T", - "-179142T", - "-179144T", - "-179145T", - "-179146T", - "T194619C", - "T194627G" - ], - "OPG002": [ - "F54S", - "C57G" - ], - "OPG047": [ - "C48R" - ] - }, - "labels": { - "aa": "OPG002: F54S, C57G; OPG047: C48R" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000031", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.20" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G53326A", - "T133078-", - "C164385T", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "C187620T" - ] - }, - "labels": { - "clade": "B.1.20" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_TX0040", - "node_attrs": { - "div": 3, - "author": { - "author": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Sheth,M.R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y.", - "value": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Sheth,M.R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_TX0040" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ320441" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-XX" - }, - "lineage": { - "value": "B.1.20" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196603A" - ] - } - } - }, - { - "name": "NODE_0000032", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.20" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-133078T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-173292A", - "-173293T", - "G177398A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-" - ] - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00484/2023", - "node_attrs": { - "div": 4, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00484/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ918695" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-02-07" - }, - "lineage": { - "value": "B.1.20" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000033", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.20" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "T597-", - "T598-", - "T599-", - "T600-", - "T164946C", - "C177899T", - "T179174-", - "T179175-", - "A196604-", - "A196605-", - "A196606-", - "A196607-", - "A196608-" - ] - } - }, - "children": [ - { - "name": "hMpxV/USA/IL-RIPHL-MPXV-050-0058/2023", - "node_attrs": { - "div": 10, - "author": { - "author": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S.", - "value": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S." - }, - "strain_original": { - "value": "hMpxV/USA/IL-RIPHL-MPXV-050-0058/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR160416" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-05-17" - }, - "lineage": { - "value": "B.1.20" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G7637A", - "G36409A", - "C101983T", - "G186105A" - ], - "OPG019": [ - "D20N" - ], - "OPG121": [ - "S65L" - ], - "OPG210": [ - "E1584K" - ] - }, - "labels": { - "aa": "OPG019: D20N; OPG121: S65L; OPG210: E1584K" - } - } - }, - { - "name": "NODE_0000034", - "node_attrs": { - "div": 7, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.20" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C20453T" - ] - } - }, - "children": [ - { - "name": "hMpxV/USA/IL-RIPHL-MPXV-050-0068/2023", - "node_attrs": { - "div": 11, - "author": { - "author": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S.", - "value": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S." - }, - "strain_original": { - "value": "hMpxV/USA/IL-RIPHL-MPXV-050-0068/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR257450" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-06-14" - }, - "lineage": { - "value": "B.1.20" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C2313T", - "T117118C", - "G170233A", - "G189274A", - "G194897A" - ], - "OPG002": [ - "D147N" - ], - "OPG005": [ - "V26I" - ], - "OPG136": [ - "M824V" - ], - "OPG198": [ - "D66N" - ] - }, - "labels": { - "aa": "OPG002: D147N; OPG005: V26I; OPG136: M824V; OPG198: D66N" - } - } - }, - { - "name": "hMpxV/USA/IL-RIPHL-MPXV-050-0061/2023", - "node_attrs": { - "div": 7, - "author": { - "author": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S.", - "value": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S." - }, - "strain_original": { - "value": "hMpxV/USA/IL-RIPHL-MPXV-050-0061/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR257451" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-05-31" - }, - "lineage": { - "value": "B.1.20" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000035", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A47741-", - "G49679-", - "A49707-", - "C62258-", - "A62259-", - "G62260-", - "T62261-", - "T62262-", - "C62305-", - "A62306-", - "A62307-", - "A62308-", - "G62309-", - "C62325-", - "C62326-", - "T62327-", - "A62328-", - "G62329-", - "T62330-", - "T62331-", - "G62332-", - "T62333-", - "A62334-", - "T62335-", - "A62336-", - "C62337-", - "T62338-", - "G62339-", - "A62340-", - "G62341-", - "A62342-", - "A62343-", - "T62344-", - "T62345-", - "G62346-", - "T62372-", - "T62373-", - "T62374-", - "T62375-", - "C62376-", - "A62404-", - "C62405-", - "T62406-", - "G62407-", - "G62408-", - "A62409-", - "A62410-", - "A62411-", - "A62412-", - "C62413-", - "T62414-", - "A62432-", - "A62433-", - "G62434-", - "T62435-", - "A62436-", - "T62437-", - "A62438-", - "T62532-", - "A62533-", - "G62552-", - "A62553-", - "G62554-", - "G62571-", - "C62572-", - "T62573-", - "T62574-", - "C62575-", - "T62576-", - "A62577-", - "G62578-", - "T62599-", - "A62623-", - "C62624-", - "T62625-", - "A62626-", - "T62627-", - "G62758-", - "T62759-", - "G62760-", - "G62761-", - "A62762-", - "A62763-", - "T62764-", - "T62765-", - "G62766-", - "A62767-", - "A62768-", - "G62769-", - "A62770-", - "T62771-", - "T62772-", - "C62773-", - "T62774-", - "A62775-", - "A62776-", - "T62777-", - "G62778-", - "G62779-", - "A62780-", - "T62781-", - "G62782-", - "A62783-", - "T62784-", - "G62785-", - "T62786-", - "T62787-", - "C62788-", - "T62789-", - "A62790-", - "C62791-", - "C62792-", - "T62793-", - "A62794-", - "T62795-", - "T62796-", - "T62797-", - "C62798-", - "A62799-", - "T62800-", - "C62801-", - "C62802-", - "G62803-", - "A62804-", - "T62805-", - "T62818-", - "C62819-", - "C62820-", - "A62821-", - "G62854-", - "G62855-", - "T62856-", - "A62857-", - "G62858-", - "T62859-", - "C62860-", - "T62861-", - "C62862-", - "T62863-", - "C62864-", - "T62865-", - "T62866-", - "T62867-", - "C62868-", - "G62869-", - "A62892-", - "T62893-", - "A62894-", - "C62895-", - "G62896-", - "A62897-", - "G62898-", - "T62899-", - "C62900-", - "A62901-", - "T62902-", - "T62903-", - "A62904-", - "T62905-", - "A62906-", - "T62907-", - "A62908-", - "C62909-", - "T62910-", - "C62911-", - "C62912-", - "T62931-", - "A62943-", - "T62944-", - "C62945-", - "G62946-", - "A62947-", - "A62965-", - "T62966-", - "C62967-", - "G62968-", - "G62980-", - "A62981-", - "A62982-", - "T62983-", - "C62984-", - "C62985-", - "G62986-", - "G62987-", - "A62988-", - "A62989-", - "C62990-", - "A62991-", - "T62992-", - "T63023-", - "G63024-", - "G63025-", - "T63026-", - "A63027-", - "A63028-", - "G63029-", - "A63030-", - "A63031-", - "A63042-", - "T63075-", - "T63076-", - "G63077-", - "A63078-", - "G63079-", - "A63080-", - "C63081-", - "T63082-", - "T63083-", - "G63084-", - "A63085-", - "T63086-", - "A63102-", - "T63103-", - "T63104-", - "C63143-", - "G63144-", - "T63145-", - "C63146-", - "G63147-", - "A63148-", - "C63149-", - "G63150-", - "C63151-", - "C63152-", - "A63153-", - "A63167-", - "T63168-", - "G63169-", - "G63170-", - "A63171-", - "G63172-", - "T63173-", - "T63239-", - "C63240-", - "T63241-", - "C63242-", - "G63243-", - "T63244-", - "A63245-", - "C63246-", - "G63247-", - "T63255-", - "T63256-", - "C63257-", - "C63258-", - "A63259-", - "T63260-", - "G63261-", - "A63262-", - "T63263-", - "C63264-", - "A63265-", - "A63266-", - "G63267-", - "A63268-", - "G63269-", - "T63270-", - "G63271-", - "A63272-", - "T63273-", - "T63274-", - "T63275-", - "G63276-", - "A63277-", - "G63278-", - "A63279-", - "A63280-", - "C63281-", - "A63282-", - "T63283-", - "C63284-", - "C63285-", - "A63311-", - "C63312-", - "A63313-", - "G63314-", - "T63315-", - "T63328-", - "A63329-", - "A63330-", - "T63331-", - "T63347-", - "A63348-", - "C63365-", - "G63366-", - "T63367-", - "T63368-", - "T63369-", - "A63370-", - "A63371-", - "T63385-", - "C63386-", - "T63387-", - "A63388-", - "A63389-", - "C63390-", - "G63391-", - "G63392-", - "A63393-", - "G63394-", - "A63395-", - "C63396-", - "A63397-", - "A63398-", - "T63399-", - "T63400-", - "T63401-", - "T63402-", - "T63403-", - "T63404-", - "G63405-", - "G63406-", - "T63407-", - "A63408-", - "G63409-", - "G63410-", - "T63411-", - "T63412-", - "T63413-", - "T63414-", - "A63415-", - "G63416-", - "A63417-", - "G63418-", - "A63419-", - "C63420-", - "T63421-", - "T63422-", - "T63423-", - "G63424-", - "A63425-", - "A63426-", - "G63427-", - "C63428-", - "T63429-", - "A63430-", - "C63431-", - "T63432-", - "T63433-", - "G63434-", - "T63435-", - "T63436-", - "T63437-", - "A63438-", - "A63439-", - "C63440-", - "A63441-", - "A63442-", - "A63443-", - "G63444-", - "T63445-", - "T63446-", - "A63447-", - "T63448-", - "T63449-", - "C63450-", - "A63451-", - "T63452-", - "C63453-", - "G63454-", - "T63455-", - "C63456-", - "C112408T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A" - ], - "OPG068": [ - "E493X", - "T503X", - "*568X" - ], - "OPG081": [ - "L8X", - "T9-", - "A10X", - "*80X" - ], - "OPG082": [ - "M1-", - "N2-", - "N3-", - "F4-", - "V5-", - "K6-", - "Q7-", - "V8-", - "A9-", - "S10-", - "K11-", - "S12-", - "L13-", - "K14-", - "P15-", - "T16-", - "K17-", - "K18-", - "L19-", - "S20-", - "P21-", - "L22-", - "D23X", - "L28-", - "N29-", - "E30X", - "F35X", - "N36X", - "Y41X", - "Y42X", - "G46X", - "L47-", - "F48X", - "E56X", - "D57-", - "V58-", - "L59-", - "K60-", - "S61-", - "L62-", - "L63-", - "I64-", - "M65-", - "E66-", - "A69X", - "Y70-", - "E71-", - "K72X", - "T94-", - "P95-", - "F96X", - "T100X", - "G101-", - "V102-", - "D103-", - "D104X", - "N117-", - "I123-", - "K124-", - "S125-", - "Q126-", - "N137X", - "V141X", - "L142-", - "T143-", - "T144X", - "N154X", - "V155-", - "P156-", - "D157-", - "S158X", - "S162X", - "I163X", - "F169X", - "D170-", - "I174X", - "G181-", - "V182-", - "Y183-", - "N184-", - "D185-", - "S186-", - "Y187-", - "P195X", - "K196-", - "E197-", - "R198-", - "L199-", - "P200X", - "L211X", - "E212X", - "L216X", - "S217-", - "D218-", - "E219-", - "I220-", - "G221-", - "R222-", - "T223-", - "S224-", - "S225-", - "I226-", - "R227-", - "I228-", - "F229-", - "N230-", - "S231-", - "T232X", - "I276-", - "V277X", - "N285X", - "S292X", - "R293-", - "S294-", - "T300X", - "H301X", - "L307X", - "Y339-", - "T340-", - "Y341X", - "S347-", - "F348-", - "P349-", - "V350X", - "K359X", - "K360-", - "K361X", - "V369X", - "N370-", - "S371-", - "Q372-", - "Y373-", - "T374-", - "T375-", - "R376-", - "L382-", - "*383X" - ], - "OPG083": [ - "D421-", - "D422-", - "E423-", - "*424-" - ], - "OPG131": [ - "L157F" - ] - }, - "labels": { - "aa": "OPG068: E493X, T503X, *568X; OPG081: L8X, T9-, A10X, *80X; OPG082: M1-, N2-, N3-, F4-, V5-, K6-, Q7-, V8-, A9-, S10-, K11-, S12-, L13-, K14-, P15-, T16-, K17-, K18-, L19-, S20-, P21-, L22-, D23X, L28-, N29-, E30X, F35X, N36X, Y41X, Y42X, G46X, L47-, F48X, E56X, D57-, V58-, L59-, K60-, S61-, L62-, L63-, I64-, M65-, E66-, A69X, Y70-, E71-, K72X, T94-, P95-, F96X, T100X, G101-, V102-, D103-, D104X, N117-, I123-, K124-, S125-, Q126-, N137X, V141X, L142-, T143-, T144X, N154X, V155-, P156-, D157-, S158X, S162X, I163X, F169X, D170-, I174X, G181-, V182-, Y183-, N184-, D185-, S186-, Y187-, P195X, K196-, E197-, R198-, L199-, P200X, L211X, E212X, L216X, S217-, D218-, E219-, I220-, G221-, R222-, T223-, S224-, S225-, I226-, R227-, I228-, F229-, N230-, S231-, T232X, I276-, V277X, N285X, S292X, R293-, S294-, T300X, H301X, L307X, Y339-, T340-, Y341X, S347-, F348-, P349-, V350X, K359X, K360-, K361X, V369X, N370-, S371-, Q372-, Y373-, T374-, T375-, R376-, L382-, *383X; OPG083: D421-, D422-, E423-, *424-; OPG131: L157F" - } - }, - "children": [ - { - "name": "26012023_neck", - "node_attrs": { - "div": 7, - "author": { - "author": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K.", - "value": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K." - }, - "strain_original": { - "value": "26012023_neck" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ672573" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-01-26" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T2640-", - "G2641-", - "T2642-", - "A2643-", - "T2644-", - "T2645-", - "C2646-", - "G2647-", - "G6878A", - "C40894T", - "T47699-", - "A47700-", - "T47742-", - "T47743-", - "A47744-", - "G47745-", - "G47746-", - "A47747-", - "C47748-", - "T47749-", - "A47750-", - "C47751-", - "T47752-", - "A47753-", - "C47754-", - "T47755-", - "C47756-", - "T47757-", - "A47758-", - "G47759-", - "A47760-", - "A47761-", - "G47762-", - "A47763-", - "T47764-", - "A47765-", - "T47766-", - "A47767-", - "G47768-", - "C47769-", - "A47770-", - "C47771-", - "C47772-", - "A47773-", - "T47774-", - "C47775-", - "T47776-", - "A47777-", - "T47778-", - "T47779-", - "C47780-", - "C47781-", - "A47782-", - "A47783-", - "A47784-", - "T47785-", - "A47786-", - "A47787-", - "T47788-", - "C47789-", - "A47790-", - "G47791-", - "A47792-", - "A47793-", - "A47794-", - "A47795-", - "C47796-", - "T47797-", - "T47798-", - "A47799-", - "T47800-", - "A47801-", - "A47802-", - "A47803-", - "C47804-", - "T47805-", - "A47806-", - "T47807-", - "T47808-", - "C47809-", - "T47810-", - "C47811-", - "G47812-", - "G47813-", - "A47814-", - "C47815-", - "A47816-", - "T47817-", - "T47818-", - "T47819-", - "C47820-", - "A47821-", - "G47822-", - "T47823-", - "C47824-", - "A47825-", - "T47826-", - "T47827-", - "G47828-", - "G47829-", - "C47830-", - "G47946-", - "A47947-", - "T47948-", - "A47949-", - "T47950-", - "A47951-", - "G47952-", - "T47953-", - "T47954-", - "G47955-", - "A47956-", - "A47957-", - "T47958-", - "C47959-", - "A47960-", - "T47961-", - "G47962-", - "T47963-", - "A47964-", - "T47965-", - "G47966-", - "T48032-", - "T48033-", - "A48034-", - "T48060-", - "A48061-", - "G48062-", - "G48063-", - "A48112-", - "A48113-", - "T48114-", - "A48115-", - "G48116-", - "T48117-", - "A48161-", - "T48162-", - "A48163-", - "G48164-", - "T48165-", - "A48166-", - "G48167-", - "T48168-", - "G48169-", - "T48170-", - "A48171-", - "G48172-", - "T48173-", - "A48174-", - "T48175-", - "C48176-", - "A48177-", - "T48178-", - "A48179-", - "G48180-", - "A48181-", - "T48182-", - "A48183-", - "A48184-", - "C48185-", - "T48186-", - "C48187-", - "T48188-", - "C48189-", - "T48190-", - "T48191-", - "C48192-", - "T48193-", - "A48194-", - "T48195-", - "A48196-", - "A48197-", - "A48198-", - "A48199-", - "A48200-", - "A48201-", - "T48202-", - "G48203-", - "G48204-", - "A48205-", - "T48206-", - "T48207-", - "T48208-", - "T48209-", - "A48210-", - "T48211-", - "T48212-", - "C48213-", - "G48214-", - "T48215-", - "A48216-", - "G48217-", - "A48218-", - "A48219-", - "A48220-", - "G48221-", - "T48222-", - "A48223-", - "T48224-", - "C48225-", - "T48226-", - "A48289-", - "T48290-", - "A48318-", - "A48319-", - "G48320-", - "T48321-", - "A48322-", - "T48323-", - "C48324-", - "T48325-", - "A48326-", - "G48327-", - "T48366-", - "T48382-", - "T48383-", - "T48384-", - "T48385-", - "T48386-", - "G48387-", - "T48388-", - "T48389-", - "T48390-", - "T48391-", - "C48392-", - "A48415-", - "A48416-", - "G48417-", - "T48418-", - "A48419-", - "T48420-", - "A48421-", - "C48422-", - "G48423-", - "A48424-", - "A48425-", - "G48426-", - "C48427-", - "G48428-", - "G48429-", - "T48430-", - "T48431-", - "T48432-", - "A48571-", - "A48572-", - "T48573-", - "A48574-", - "C48575-", - "A48576-", - "T48577-", - "G48578-", - "G48579-", - "A48580-", - "C48581-", - "G48582-", - "A48583-", - "A48584-", - "T48585-", - "T48586-", - "A48587-", - "G48588-", - "G48589-", - "A48590-", - "G48591-", - "A48592-", - "A48593-", - "C48594-", - "T48595-", - "T48596-", - "A48597-", - "T48598-", - "A48599-", - "G48600-", - "G48601-", - "C48602-", - "G48603-", - "T48604-", - "A48605-", - "A48606-", - "A48607-", - "T48608-", - "T48609-", - "A48610-", - "T48611-", - "G48612-", - "A48613-", - "C48614-", - "T48615-", - "T48616-", - "A48617-", - "G48618-", - "T48619-", - "C48648-", - "C48649-", - "C48650-", - "A48651-", - "T48652-", - "C48653-", - "A48654-", - "A48655-", - "A48656-", - "G48657-", - "A48658-", - "T48659-", - "A48660-", - "T48661-", - "G48662-", - "G48663-", - "A48664-", - "A48665-", - "A48666-", - "T48667-", - "C48668-", - "A48669-", - "T48670-", - "T48671-", - "T48672-", - "T48673-", - "T48674-", - "A48760-", - "A48761-", - "G48762-", - "A48763-", - "T48764-", - "A48765-", - "C48766-", - "A48767-", - "G48768-", - "G48769-", - "C48770-", - "A48771-", - "T48772-", - "A48773-", - "G48774-", - "A48775-", - "G48776-", - "T48777-", - "T48778-", - "T48779-", - "G48780-", - "C48781-", - "G48782-", - "G48783-", - "A48784-", - "T48785-", - "A48786-", - "A48787-", - "T48788-", - "A48790T", - "G48798T", - "A48822-", - "C48823-", - "T48824-", - "G48825-", - "G48826-", - "T48827-", - "A48828-", - "G48829-", - "A48830-", - "A48831-", - "T48832-", - "A48833-", - "G48834-", - "T48835-", - "C48836-", - "C48837-", - "A48838-", - "T48839-", - "A48840-", - "G48841-", - "C48842-", - "A48843-", - "A48844-", - "T48845-", - "C48846-", - "T48847-", - "A48848-", - "A48849-", - "C48850-", - "A48851-", - "G48852-", - "A48853-", - "A48854-", - "A48855-", - "C48856-", - "G48857-", - "T48858-", - "T48859-", - "T48860-", - "A48861-", - "G48862-", - "G48863-", - "G48864-", - "A48865-", - "T48866-", - "T48867-", - "A48868-", - "T48869-", - "A48870-", - "T48871-", - "C48872-", - "T48873-", - "T48874-", - "T48875-", - "C48876-", - "C48877T", - "A48909-", - "A48910-", - "C48911-", - "G48912-", - "A48913-", - "A48914-", - "A48915-", - "G48916-", - "T48917-", - "A48918-", - "T48919-", - "T48968-", - "G48969-", - "A48970-", - "T48971-", - "A48972-", - "A48973-", - "A48974-", - "A48975-", - "T48976-", - "T48977-", - "C48978-", - "T48979-", - "T48980-", - "A48981-", - "G48982-", - "T48983-", - "T48984-", - "A48985-", - "T48986-", - "A48987-", - "T48988-", - "A48989-", - "T48990-", - "A48991-", - "C48992-", - "T48993-", - "C48994-", - "T48995-", - "G48996-", - "A48997-", - "G48998-", - "A48999-", - "T49000-", - "A49001-", - "A49002-", - "A49003-", - "A49004-", - "C49005-", - "A49006-", - "G49007-", - "G49008-", - "G49009-", - "A49010-", - "C49011-", - "G49012-", - "C49013-", - "G49014-", - "T49015-", - "T49016-", - "A49017-", - "A49018-", - "T49019-", - "A49020-", - "A49021-", - "A49022-", - "A49023-", - "A49024-", - "C49025-", - "A49026-", - "T49027-", - "G49028-", - "C49029-", - "T49030-", - "T49031-", - "A49032-", - "A49033-", - "G49034-", - "T49035-", - "T49156-", - "T49157-", - "A49158-", - "T49159-", - "T49160-", - "A49161-", - "G49162-", - "T49163-", - "T49164-", - "T49165-", - "T49166-", - "T49167-", - "A49168-", - "C49169-", - "A49170-", - "A49171-", - "A49172-", - "G49173-", - "C49174-", - "T49175-", - "A49176-", - "A49177-", - "T49178-", - "T49179-", - "T49180-", - "T49181-", - "A49182-", - "T49183-", - "T49184-", - "A49185-", - "A49186-", - "C49187-", - "G49188-", - "G49189-", - "T49190-", - "A49191-", - "A49192-", - "T49193-", - "A49194-", - "C49195-", - "A49196-", - "T49197-", - "T49198-", - "T49199-", - "A49200-", - "T49201-", - "T49202-", - "A49203-", - "G49204-", - "T49205-", - "G49206-", - "A49207-", - "T49208-", - "A49209-", - "G49210-", - "A49211-", - "A49212-", - "C49213-", - "G49214-", - "T49215-", - "T49216-", - "T49217-", - "A49218-", - "A49219-", - "C49220-", - "G49221-", - "A49222-", - "T49223-", - "G49224-", - "A49225-", - "C49226-", - "T49227-", - "T49228-", - "A49229-", - "T49230-", - "T49231-", - "C49232-", - "A49233-", - "G49234-", - "A49235-", - "G49236-", - "T49237-", - "T49238-", - "G49239-", - "T49240-", - "T49241-", - "G49242-", - "T49243-", - "T49244-", - "C49245-", - "A49246-", - "A49247-", - "A49248-", - "T49249-", - "A49250-", - "G49251-", - "A49252-", - "T49253-", - "C49254-", - "C49255-", - "C49256-", - "G49257-", - "A49258-", - "A49259-", - "T49260-", - "A49261-", - "T49262-", - "T49263-", - "T49264-", - "C49265-", - "G49266-", - "A49267-", - "T49268-", - "A49269-", - "A49270-", - "T49271-", - "G49272-", - "A49273-", - "A49274-", - "C49275-", - "G49276-", - "A49277-", - "A49278-", - "T49279-", - "T49280-", - "A49281-", - "T49282-", - "G49283-", - "T49284-", - "C49285-", - "T49286-", - "T49287-", - "T49288-", - "A49289-", - "T49290-", - "T49291-", - "C49292-", - "T49293-", - "A49294-", - "T49295-", - "A49296-", - "C49297-", - "G49298-", - "A49299-", - "G49300-", - "T49301-", - "G49302-", - "C49303-", - "T49304-", - "G49305-", - "C49306-", - "G49307-", - "G49308-", - "A49309-", - "C49310-", - "A49311-", - "T49312-", - "T49313-", - "A49314-", - "A49315-", - "A49316-", - "C49317-", - "G49318-", - "A49319-", - "T49320-", - "T49321-", - "T49322-", - "G49323-", - "A49324-", - "T49325-", - "G49326-", - "A49327-", - "G49328-", - "T49329-", - "T49330-", - "A49331-", - "G49332-", - "A49333-", - "T49334-", - "A49335-", - "T49336-", - "T49337-", - "A49338-", - "A49339-", - "T49340-", - "A49341-", - "A49342-", - "C49343-", - "A49344-", - "G49345-", - "T49346-", - "T49347-", - "A49348-", - "T49349-", - "A49350-", - "T49351-", - "A49352-", - "T49353-", - "C49354-", - "T49355-", - "A49356-", - "A49357-", - "G49397-", - "G49398-", - "A49399-", - "T49400-", - "G49401-", - "A49402-", - "T49403-", - "A49404-", - "T49405-", - "G49406-", - "A49407-", - "A49408-", - "G49409-", - "A49410-", - "T49473-", - "T49474-", - "G49475-", - "C49476-", - "A49477-", - "C49478-", - "G49479-", - "A49480-", - "G49481-", - "T49482-", - "C49483-", - "G49484-", - "G49485-", - "A49486-", - "T49487-", - "C49488-", - "C49489-", - "C49490-", - "A49491-", - "T49492-", - "G49493-", - "G49494-", - "T49495-", - "C49496-", - "A49497-", - "T49498-", - "A49499-", - "G49500-", - "A49501-", - "G49502-", - "A49503-", - "A49504-", - "C49505-", - "G49506-", - "G49507-", - "A49508-", - "A49509-", - "T49510-", - "A49511-", - "C49512-", - "T49513-", - "A49514-", - "A49515-", - "A49516-", - "G49517-", - "A49518-", - "A49519-", - "A49520-", - "C49521-", - "T49522-", - "G49523-", - "T49524-", - "C49525-", - "A49526-", - "T49527-", - "C49528-", - "T49529-", - "A49530-", - "T49531-", - "A49532-", - "A49533-", - "A49534-", - "A49535-", - "T49536-", - "C49537-", - "C49538-", - "A49539-", - "A49540-", - "G49541-", - "A49542-", - "G49543-", - "T49544-", - "A49545-", - "G49546-", - "A49547-", - "C49548-", - "G49549-", - "G49550-", - "C49551-", - "T49552-", - "G49553-", - "A49554-", - "A49555-", - "C49556-", - "T49557-", - "T49558-", - "G49559-", - "T49560-", - "T49561-", - "T49562-", - "A49563-", - "G49564-", - "C49565-", - "A49566-", - "A49567-", - "A49568-", - "A49569-", - "A49570-", - "C49571-", - "A49572-", - "T49573-", - "T49574-", - "T49575-", - "T49576-", - "A49577-", - "A49578-", - "A49579-", - "A49580-", - "T49581-", - "A49582-", - "T49583-", - "T49584-", - "A49585-", - "T49586-", - "T49587-", - "T49588-", - "A49589-", - "G49590-", - "A49591-", - "C49592-", - "G49593-", - "G49594-", - "A49595-", - "C49596-", - "A49597-", - "A49598-", - "T49599-", - "T49600-", - "G49601-", - "G49602-", - "C49603-", - "T49604-", - "C49605-", - "G49606-", - "T49607-", - "C49608-", - "T49609-", - "A49610-", - "G49611-", - "G49612-", - "T49613-", - "C49614-", - "T49615-", - "T49616-", - "G49617-", - "T49618-", - "G49619-", - "T49620-", - "T49621-", - "A49622-", - "G49623-", - "A49624-", - "T49625-", - "G49626-", - "A49627-", - "T49628-", - "T49629-", - "A49630-", - "T49631-", - "A49632-", - "A49633-", - "A49634-", - "G49635-", - "G49636-", - "A49637-", - "G49638-", - "A49639-", - "C49640-", - "T49641-", - "T49642-", - "A49643-", - "T49644-", - "T49645-", - "A49646-", - "G49647-", - "T49648-", - "T49649-", - "A49650-", - "A49651-", - "A49652-", - "A49653-", - "T49654-", - "G49655-", - "A49656-", - "T49657-", - "A49658-", - "A49659-", - "A49660-", - "C49661-", - "C49662-", - "A49663-", - "T49664-", - "C49665-", - "T49666-", - "C49667-", - "A49668-", - "A49669-", - "A49670-", - "T49671-", - "C49672-", - "T49673-", - "G49674-", - "T49675-", - "G49676-", - "G49677-", - "A49678-", - "G49680-", - "A49681-", - "T49682-", - "G49683-", - "T49684-", - "A49685-", - "T49686-", - "C49687-", - "C49688-", - "G49689-", - "C49690-", - "A49691-", - "T49692-", - "T49693-", - "C49694-", - "G49695-", - "T49696-", - "T49697-", - "A49698-", - "G49699-", - "A49700-", - "T49701-", - "T49702-", - "T49703-", - "T49704-", - "C49705-", - "T49706-", - "C49708-", - "A49709-", - "T62643-", - "G62644-", - "G62645-", - "A62646-", - "C62647-", - "T62648-", - "C62649-", - "G62650-", - "C62651-", - "G62652-", - "T62653-", - "T62654-", - "T62655-", - "A62656-", - "G62657-", - "A62658-", - "G62659-", - "G62660-", - "A62661-", - "G62662-", - "T62663-", - "G62664-", - "A62665-", - "A62666-", - "C62667-", - "G62668-", - "T62669-", - "C62670-", - "C67724T", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T178558-", - "G178559-", - "A178560-", - "T178561-", - "T178562-", - "A178563-", - "T178564-", - "A178565-", - "C178566-", - "A178567-", - "T178568-", - "C178569-", - "G178570-", - "G178571-", - "T178572-", - "A178573-", - "C178574-", - "A178575-", - "T178576-", - "A178577-", - "C178578-", - "A178579-", - "G178580-", - "T178581-", - "A178582-", - "A178583-", - "A178584-", - "T178585-", - "A178586-", - "G178587-", - "C178588-", - "A178589-", - "T178590-", - "A178591-", - "G178592-", - "A178593-", - "T178594-", - "A178595-", - "T178596-", - "G178597-", - "G178598-", - "A178599-", - "G178600-", - "G178601-", - "A178602-", - "G178603-", - "G178604-", - "A178605-", - "T178606-", - "A178607-", - "C178608-", - "A178609-", - "A178610-", - "A178611-", - "T178612-", - "A178613-", - "T178614-", - "T178615-", - "T178616-", - "C178617-", - "A178618-", - "A178619-", - "A178620-", - "T178621-", - "A178622-", - "A178623-", - "A178624-", - "G178625-", - "T178626-", - "T178627-", - "A178628-", - "T178629-", - "G178630-", - "A178631-", - "G178632-", - "A178633-", - "T178634-", - "A178635-", - "C178636-", - "G178637-", - "C178638-", - "G178639-", - "C178640-", - "T178641-", - "G178642-", - "T178643-", - "C178644-", - "A178645-", - "A178646-", - "T178647-", - "A178648-", - "A178649-", - "T178650-", - "A178651-", - "T178652-", - "A178653-", - "T178654-", - "G178655-", - "G178656-", - "A178657-", - "A178658-", - "G178659-", - "A178660-", - "C178661-", - "A178662-", - "T178663-", - "T178664-", - "A178665-", - "C178666-", - "C178667-", - "T178668-", - "A178669-", - "A178670-", - "C178671-", - "T178672-", - "T178673-", - "C178674-", - "T178675-", - "G178676-", - "A178677-", - "A178678-", - "C178679-", - "T178680-", - "G178681-", - "G178682-", - "A178683-", - "A178684-", - "C178685-", - "T178686-", - "A178687-", - "T178688-", - "A178689-", - "A178690-", - "A178691-", - "T178692-", - "C178693-", - "C178694-", - "A178695-", - "G178696-", - "G178697-", - "C178698-", - "T178699-", - "C178700-", - "T178701-", - "C178702-", - "G178703-", - "C178704-", - "A178705-", - "T178706-", - "A178707-", - "A178708-", - "A178709-", - "G178710-", - "A178711-", - "T178712-", - "G178713-", - "A178714-", - "A178715-", - "T178716-", - "A178717-", - "T178718-", - "A178719-", - "T178720-", - "A178721-", - "T178722-", - "G178723-", - "T178724-", - "T178725-", - "G178726-", - "T178727-", - "A178728-", - "T178729-", - "G178730-", - "C178731-", - "G178732-", - "A178733-", - "C178734-", - "A178735-", - "T178736-", - "C178737-", - "A178738-", - "A178739-", - "A178740-", - "G178741-", - "A178742-", - "T178743-", - "G178744-", - "A178745-", - "A178746-", - "A178747-", - "A178748-", - "A178749-", - "A178750-", - "T178751-", - "G178752-", - "T178753-", - "T178754-", - "A178755-", - "A178756-", - "G178757-", - "A178758-", - "C178759-", - "T178760-", - "T178761-", - "A178762-", - "T178763-", - "A178764-", - "T178765-", - "A178766-", - "T178767-", - "T178768-", - "T178769-", - "A178770-", - "G178771-", - "A178772-", - "T178773-", - "A178774-", - "T178775-", - "A178776-", - "A178777-", - "C178778-", - "A178779-", - "C178780-", - "G178781-", - "A178782-", - "A178783-", - "T178784-", - "A178785-", - "T178786-", - "G178787-", - "T178788-", - "A178789-", - "T178790-", - "G178791-", - "A178792-", - "C178793-", - "G178794-", - "G178795-", - "A178796-", - "T178797-", - "G178798-", - "G178799-", - "G178800-", - "A178801-", - "A178802-", - "T178803-", - "T178804-", - "G178805-", - "G178806-", - "T178807-", - "A178808-", - "A178809-", - "C178810-", - "G178811-", - "A178812-", - "T178813-", - "G178814-", - "A178815-", - "C178816-", - "A178817-", - "G178818-", - "A178819-", - "A178820-", - "A178821-", - "G178822-", - "C178823-", - "A178824-", - "G178825-", - "A178826-", - "T178827-", - "T178828-", - "G178829-", - "T178830-", - "C178831-", - "A178832-", - "G178833-", - "C178834-", - "T178835-", - "C178836-", - "T178837-", - "G178838-", - "C178839-", - "A178840-", - "T178841-", - "A178842-", - "C178843-", - "T178844-", - "A178845-", - "T178846-", - "T178847-", - "C178848-", - "T178849-", - "T178850-", - "C178851-", - "A178852-", - "T178853-", - "G178854-", - "A178855-", - "C178856-", - "A178857-", - "A178858-", - "T178859-", - "A178860-", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-", - "G178879-", - "T178880-", - "T178881-", - "A178882-", - "T178883-", - "G178884-", - "A178885-", - "A178886-", - "G178887-", - "C178888-", - "G178889-", - "T178890-", - "A178891-", - "T178892-", - "A178893-", - "T178894-", - "G178895-", - "T178896-", - "T178897-", - "A178898-", - "C178899-", - "A178900-", - "A178901-", - "G178902-", - "A178903-", - "T178904-", - "A178905-", - "C178906-", - "A178907-", - "T178908-", - "T178909-", - "T178910-", - "A178911-", - "A178912-", - "T178913-", - "G178914-", - "T178915-", - "G178916-" - ], - "OPG060": [ - "G97R" - ], - "OPG068": [ - "M1-", - "D2-", - "F3-", - "I4-", - "R5-", - "R6-", - "K7-", - "Y8-", - "L9X", - "N30X", - "K40-", - "Y41-", - "L42-", - "V43X", - "L56X", - "F61X", - "F62-", - "V63-", - "F64-", - "K72X", - "V73-", - "Y74-", - "E75-", - "A76-", - "V77-", - "L78X", - "E124X", - "Y125-", - "M126-", - "D127-", - "E128-", - "L129-", - "G130-", - "E131-", - "L132-", - "I133-", - "G134-", - "V135-", - "N136-", - "Y137-", - "D138-", - "L139-", - "V140X", - "P150-", - "I151-", - "K152-", - "D153-", - "M154-", - "E155-", - "I156-", - "I157-", - "F158-", - "K187X", - "D188-", - "T189-", - "G190-", - "I191-", - "E192-", - "F193-", - "A194-", - "D195-", - "N196-", - "D197V", - "D200Y", - "T208-", - "G209-", - "R210-", - "I211-", - "V212-", - "H213-", - "S214-", - "N215-", - "L216-", - "T217-", - "E218-", - "T219-", - "F220-", - "R221-", - "D222-", - "Y223-", - "I224-", - "F225-", - "P226X", - "N237-", - "E238-", - "S239-", - "I240X", - "Y256X", - "D257-", - "K258-", - "I259-", - "L260-", - "S261-", - "Y262-", - "I263-", - "Y264-", - "S265-", - "E266-", - "I267-", - "K268-", - "Q269-", - "G270-", - "R271-", - "V272-", - "N273-", - "K274-", - "N275-", - "M276-", - "L277-", - "K278-", - "L279X", - "F319X", - "I320-", - "S321-", - "F322-", - "Y323-", - "K324-", - "A325-", - "N326-", - "F327-", - "I328-", - "N329-", - "G330-", - "N331-", - "T332-", - "F333-", - "I334-", - "S335-", - "D336-", - "R337-", - "T338-", - "F339-", - "N340-", - "D341-", - "D342-", - "L343-", - "F344-", - "R345-", - "V346-", - "V347-", - "V348-", - "Q349-", - "I350-", - "D351-", - "P352-", - "E353-", - "Y354-", - "F355-", - "D356-", - "N357-", - "E358-", - "R359-", - "I360-", - "M361-", - "S362-", - "L363-", - "F364-", - "Y365-", - "T366-", - "S367-", - "A368-", - "A369-", - "D370-", - "I371-", - "K372-", - "R373-", - "F374-", - "D375-", - "E376-", - "L377-", - "D378-", - "I379-", - "N380-", - "N381-", - "S382-", - "Y383-", - "I384-", - "S385-", - "N386X", - "M399X", - "D400-", - "D401-", - "M402-", - "K403-", - "K404X", - "L425-", - "H426-", - "E427-", - "S428-", - "D429-", - "P430-", - "M431-", - "V432-", - "I433-", - "E434-", - "N435-", - "G436-", - "I437-", - "L438-", - "K439-", - "K440-", - "L441-", - "S442-", - "S443-", - "I444-", - "K445-", - "S446-", - "K447-", - "S448-", - "R449-", - "R450-", - "L451-", - "N452-", - "L453-", - "F454-", - "S455-", - "K456-", - "N457-", - "I458-", - "L459-", - "K460-", - "Y461-", - "Y462-", - "L463-", - "D464-", - "G465-", - "Q466-", - "L467-", - "A468-", - "R469-", - "L470-", - "G471-", - "L472-", - "V473-", - "L474-", - "D475-", - "D476-", - "Y477-", - "K478-", - "G479-", - "D480-", - "L481-", - "L482-", - "V483-", - "K484-", - "M485-", - "I486-", - "N487-", - "H488-", - "L489-", - "K490-", - "S491-", - "V492-", - "X493-", - "D494-", - "V495-", - "S496-", - "A497-", - "F498-", - "V499-", - "R500-", - "F501-", - "S502-", - "X503-" - ], - "OPG082": [ - "K261X", - "T262-", - "F263-", - "T264-", - "P265-", - "L266-", - "N267-", - "A268-", - "S269-", - "P270-" - ], - "OPG085": [ - "E270K" - ] - }, - "labels": { - "aa": "OPG060: G97R; OPG068: M1-, D2-, F3-, I4-, R5-, R6-, K7-, Y8-, L9X, N30X, K40-, Y41-, L42-, V43X, L56X, F61X, F62-, V63-, F64-, K72X, V73-, Y74-, E75-, A76-, V77-, L78X, E124X, Y125-, M126-, D127-, E128-, L129-, G130-, E131-, L132-, I133-, G134-, V135-, N136-, Y137-, D138-, L139-, V140X, P150-, I151-, K152-, D153-, M154-, E155-, I156-, I157-, F158-, K187X, D188-, T189-, G190-, I191-, E192-, F193-, A194-, D195-, N196-, D197V, D200Y, T208-, G209-, R210-, I211-, V212-, H213-, S214-, N215-, L216-, T217-, E218-, T219-, F220-, R221-, D222-, Y223-, I224-, F225-, P226X, N237-, E238-, S239-, I240X, Y256X, D257-, K258-, I259-, L260-, S261-, Y262-, I263-, Y264-, S265-, E266-, I267-, K268-, Q269-, G270-, R271-, V272-, N273-, K274-, N275-, M276-, L277-, K278-, L279X, F319X, I320-, S321-, F322-, Y323-, K324-, A325-, N326-, F327-, I328-, N329-, G330-, N331-, T332-, F333-, I334-, S335-, D336-, R337-, T338-, F339-, N340-, D341-, D342-, L343-, F344-, R345-, V346-, V347-, V348-, Q349-, I350-, D351-, P352-, E353-, Y354-, F355-, D356-, N357-, E358-, R359-, I360-, M361-, S362-, L363-, F364-, Y365-, T366-, S367-, A368-, A369-, D370-, I371-, K372-, R373-, F374-, D375-, E376-, L377-, D378-, I379-, N380-, N381-, S382-, Y383-, I384-, S385-, N386X, M399X, D400-, D401-, M402-, K403-, K404X, L425-, H426-, E427-, S428-, D429-, P430-, M431-, V432-, I433-, E434-, N435-, G436-, I437-, L438-, K439-, K440-, L441-, S442-, S443-, I444-, K445-, S446-, K447-, S448-, R449-, R450-, L451-, N452-, L453-, F454-, S455-, K456-, N457-, I458-, L459-, K460-, Y461-, Y462-, L463-, D464-, G465-, Q466-, L467-, A468-, R469-, L470-, G471-, L472-, V473-, L474-, D475-, D476-, Y477-, K478-, G479-, D480-, L481-, L482-, V483-, K484-, M485-, I486-, N487-, H488-, L489-, K490-, S491-, V492-, X493-, D494-, V495-, S496-, A497-, F498-, V499-, R500-, F501-, S502-, X503-; OPG082: K261X, T262-, F263-, T264-, P265-, L266-, N267-, A268-, S269-, P270-; OPG085: E270K" - } - } - }, - { - "name": "NODE_0000036", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A62106-", - "T62107-", - "A62108-", - "G62109-", - "A62110-", - "T62111-", - "A62112-", - "A62113-", - "A62114-", - "G62115-", - "A62116-", - "G62117-", - "T62118-", - "C62119-", - "C62120-", - "T62121-", - "A62122-", - "T62123-", - "A62124-", - "T62125-", - "A62126-", - "T62127-", - "T62128-", - "T62129-", - "G62130-", - "A62131-", - "A62132-", - "A62133-", - "A62134-", - "T62135-", - "C62136-", - "G62137-", - "T62138-", - "T62139-", - "A62140-", - "C62141-", - "G62142-", - "G62143-", - "T62144-", - "T62145-", - "C62146-", - "G62147-", - "A62148-", - "T62164-", - "G62165-", - "C62166-", - "A62167-", - "T62168-", - "T62169-", - "G62170-", - "T62171-", - "G62172-", - "A62173-", - "A62174-", - "T62175-", - "A62176-", - "T62177-", - "A62178-", - "T62179-", - "C62180-", - "A62181-", - "T62182-", - "T62183-", - "A62184-", - "G62185-", - "G62186-", - "A62187-", - "T62188-", - "T62189-", - "T62190-", - "A62191-", - "A62192-", - "C62193-", - "T62194-", - "C62195-", - "C62196-", - "T62197-", - "T62198-", - "G62199-", - "A62200-", - "C62201-", - "T62202-", - "A62203-", - "T62204-", - "C62205-", - "A62206-", - "T62207-", - "G62208-", - "G62209-", - "C62210-", - "G62211-", - "G62212-", - "T62213-", - "G62214-", - "C62215-", - "C62216-", - "A62217-", - "G62218-", - "A62219-", - "A62220-", - "A62221-", - "T62222-", - "T62223-", - "A62224-", - "C62225-", - "C62226-", - "A62227-", - "T62228-", - "C62229-", - "A62230-", - "A62231-", - "A62232-", - "A62233-", - "G62234-", - "C62235-", - "A62236-", - "T62237-", - "T62238-", - "A62239-", - "A62240-", - "T62241-", - "A62242-", - "C62243-", - "A62244-", - "G62245-", - "T62246-", - "T62247-", - "A62248-", - "T62249-", - "G62250-", - "C62251-", - "A62252-", - "G62253-", - "A62254-", - "T62255-", - "C62256-", - "G62257-", - "A62263-", - "G62264-", - "A62265-", - "A62266-", - "C62267-", - "G62268-", - "G62269-", - "T62270-", - "T62271-", - "A62272-", - "T62273-", - "A62274-", - "G62275-", - "C62276-", - "A62277-", - "T62278-", - "C62279-", - "C62280-", - "A62281-", - "C62282-", - "C62283-", - "A62284-", - "T62285-", - "T62286-", - "T62287-", - "A62288-", - "T62289-", - "A62290-", - "T62291-", - "C62292-", - "T62293-", - "A62294-", - "A62295-", - "A62296-", - "A62297-", - "A62298-", - "T62299-", - "T62300-", - "A62301-", - "G62302-", - "A62303-", - "T62304-", - "A62310-", - "A62311-", - "T62312-", - "A62313-", - "T62314-", - "G62315-", - "T62316-", - "G62317-", - "A62318-", - "C62319-", - "A62320-", - "A62321-", - "C62322-", - "G62323-", - "T62324-", - "A62347-", - "C62348-", - "G62349-", - "A62350-", - "A62351-", - "A62352-", - "C62353-", - "A62354-", - "A62355-", - "T62356-", - "T62358-", - "T62359-", - "T62360-", - "T62363-", - "A62364-", - "C62365-", - "A62366-", - "T62367-", - "A62368-", - "T62369-", - "T62370-", - "T62377-", - "T62378-", - "A62379-", - "T62380-", - "T62381-", - "A62382-", - "G62383-", - "T62384-", - "A62385-", - "A62386-", - "C62387-", - "C62388-", - "G62389-", - "A62390-", - "C62391-", - "T62392-", - "T62393-", - "A62394-", - "A62395-", - "T62396-", - "A62397-", - "G62398-", - "T62399-", - "A62400-", - "G62401-", - "G62402-", - "A62403-", - "A62415-", - "G62416-", - "A62417-", - "C62418-", - "T62419-", - "T62420-", - "G62421-", - "A62422-", - "T62423-", - "T62424-", - "A62425-", - "T62426-", - "T62427-", - "C62428-", - "T62429-", - "A62430-", - "T62431-", - "G62439-", - "A62440-", - "T62441-", - "A62442-", - "C62443-", - "C62444-", - "C62445-", - "T62446-", - "T62447-", - "C62448-", - "C62449-", - "A62450-", - "A62451-", - "A62452-", - "T62453-", - "A62454-", - "A62455-", - "T62456-", - "G62457-", - "T62458-", - "T62459-", - "C62460-", - "T62461-", - "C62462-", - "T62463-", - "T62464-", - "T62465-", - "G62466-", - "A62467-", - "T62468-", - "A62469-", - "A62470-", - "A62471-", - "A62472-", - "G62473-", - "T62474-", - "T62475-", - "C62476-", - "C62477-", - "A62478-", - "G62479-", - "A62480-", - "A62481-", - "A62482-", - "A62483-", - "T62484-", - "G62485-", - "T62486-", - "A62487-", - "G62488-", - "A62489-", - "A62490-", - "T62491-", - "T62492-", - "T62493-", - "T62494-", - "T62495-", - "T62496-", - "A62497-", - "A62498-", - "A62499-", - "A62500-", - "A62501-", - "G62502-", - "T62503-", - "T62504-", - "A62505-", - "T62506-", - "C62507-", - "T62508-", - "T62509-", - "T62510-", - "T62511-", - "G62512-", - "C62513-", - "T62514-", - "A62515-", - "T62516-", - "T62517-", - "A62518-", - "C62519-", - "T62520-", - "A62521-", - "A62522-", - "T62523-", - "A62524-", - "T62525-", - "C62526-", - "G62527-", - "T62528-", - "G62529-", - "G62530-", - "T62531-", - "G62534-", - "A62535-", - "C62536-", - "G62537-", - "C62538-", - "T62539-", - "T62540-", - "A62541-", - "T62542-", - "T62543-", - "A62544-", - "T62545-", - "T62546-", - "A62547-", - "A62548-", - "T62549-", - "A62550-", - "T62551-", - "T62555-", - "G62556-", - "A62557-", - "T62558-", - "G62559-", - "A62560-", - "A62561-", - "A62562-", - "T62563-", - "C62564-", - "C62565-", - "A62566-", - "C62567-", - "A62568-", - "C62569-", - "C62570-", - "A62579-", - "T62580-", - "A62581-", - "T62582-", - "C62583-", - "G62584-", - "C62585-", - "T62586-", - "T62587-", - "T62588-", - "T62589-", - "A62590-", - "T62591-", - "T62592-", - "T62593-", - "C62594-", - "C62595-", - "A62596-", - "C62597-", - "A62598-", - "T62600-", - "A62601-", - "G62602-", - "A62603-", - "T62604-", - "G62605-", - "G62606-", - "T62607-", - "A62608-", - "A62609-", - "A62610-", - "T62611-", - "C62612-", - "C62613-", - "A62614-", - "A62615-", - "T62616-", - "A62617-", - "G62618-", - "T62619-", - "G62620-", - "A62621-", - "A62622-", - "C62628-", - "T62691-", - "T62692-", - "C62693-", - "G62694-", - "T62695-", - "C62696-", - "A62697-", - "A62698-", - "A62699-", - "T62700-", - "G62701-", - "A62702-", - "A62703-", - "T62704-", - "A62705-", - "A62706-", - "A62707-", - "C62708-", - "A62709-", - "A62710-", - "T62711-", - "T62712-", - "T62713-", - "C62714-", - "A62715-", - "C62716-", - "A62717-", - "A62718-", - "A62719-", - "T62720-", - "G62721-", - "G62722-", - "A62723-", - "T62724-", - "G62725-", - "T62726-", - "T62727-", - "A62728-", - "A62729-", - "T62730-", - "G62731-", - "T62732-", - "A62733-", - "T62734-", - "T62735-", - "A62736-", - "G62737-", - "T62738-", - "A62739-", - "G62740-", - "G62741-", - "A62742-", - "A62743-", - "A62744-", - "T62745-", - "T62746-", - "T62747-", - "T62748-", - "T62749-", - "T62750-", - "G62751-", - "A62752-", - "C62753-", - "G62754-", - "C62755-", - "T62756-", - "A62757-", - "A62806-", - "A62807-", - "C62808-", - "A62809-", - "T62810-", - "G62811-", - "T62812-", - "T62813-", - "A62814-", - "A62815-", - "T62816-", - "T62817-", - "A62822-", - "T62823-", - "A62824-", - "C62825-", - "C62826-", - "A62827-", - "A62828-", - "C62829-", - "G62830-", - "G62831-", - "T62832-", - "T62833-", - "T62834-", - "T62835-", - "A62836-", - "A62837-", - "T62838-", - "A62839-", - "T62840-", - "T62841-", - "T62842-", - "C62843-", - "G62844-", - "A62845-", - "T62846-", - "G62847-", - "A62848-", - "T62849-", - "A62850-", - "T62851-", - "A62852-", - "C62853-", - "G62870-", - "A62871-", - "C62872-", - "T62873-", - "T62874-", - "A62875-", - "T62876-", - "A62877-", - "T62878-", - "A62879-", - "G62880-", - "C62881-", - "T62882-", - "T62883-", - "A62884-", - "T62885-", - "T62886-", - "C62887-", - "C62888-", - "A62889-", - "C62890-", - "A62891-", - "A62913-", - "A62914-", - "A62915-", - "A62916-", - "A62917-", - "A62918-", - "C62919-", - "A62920-", - "A62921-", - "A62922-", - "A62923-", - "T62924-", - "A62925-", - "A62926-", - "C62927-", - "T62928-", - "A62929-", - "G62930-", - "A62932-", - "T62933-", - "A62934-", - "A62935-", - "A62936-", - "A62937-", - "T62938-", - "C62939-", - "T62940-", - "G62941-", - "T62942-", - "A62948-", - "T62949-", - "G62950-", - "G62951-", - "G62952-", - "A62953-", - "A62954-", - "A62955-", - "A62956-", - "A62957-", - "C62958-", - "G62959-", - "A62960-", - "A62961-", - "A62962-", - "T62963-", - "T62964-", - "A62969-", - "T62970-", - "A62971-", - "T62972-", - "A62973-", - "G62974-", - "G62975-", - "T62976-", - "A62977-", - "T62978-", - "A62979-", - "T62993-", - "G62994-", - "A62995-", - "A62996-", - "C62997-", - "G62998-", - "T62999-", - "A63000-", - "T63001-", - "T63002-", - "A63003-", - "A63004-", - "T63005-", - "A63006-", - "C63007-", - "T63008-", - "T63009-", - "A63010-", - "A63011-", - "T63012-", - "T63013-", - "C63014-", - "T63015-", - "T63016-", - "T63017-", - "T63018-", - "T63019-", - "C63020-", - "A63021-", - "G63022-", - "C63032-", - "C63033-", - "G63034-", - "A63035-", - "T63036-", - "A63037-", - "G63038-", - "G63039-", - "T63040-", - "T63041-", - "T63043-", - "T63044-", - "G63045-", - "A63046-", - "C63047-", - "A63048-", - "T63049-", - "T63050-", - "G63051-", - "T63052-", - "A63053-", - "T63054-", - "G63055-", - "G63056-", - "T63057-", - "T63058-", - "T63059-", - "T63060-", - "A63061-", - "A63062-", - "A63063-", - "T63064-", - "A63065-", - "T63066-", - "T63067-", - "C63068-", - "T63069-", - "A63070-", - "T63071-", - "A63072-", - "A63073-", - "C63074-", - "A63087-", - "G63088-", - "A63089-", - "T63090-", - "A63091-", - "T63092-", - "T63093-", - "A63094-", - "A63095-", - "T63096-", - "G63097-", - "A63098-", - "C63099-", - "G63100-", - "A63101-", - "G63105-", - "A63106-", - "A63107-", - "A63108-", - "A63109-", - "T63110-", - "T63111-", - "A63112-", - "T63113-", - "T63114-", - "T63115-", - "T63116-", - "T63117-", - "A63118-", - "T63119-", - "C63120-", - "A63121-", - "C63122-", - "C63123-", - "A63124-", - "C63125-", - "G63126-", - "T63127-", - "G63128-", - "T63129-", - "G63130-", - "T63131-", - "T63132-", - "T63133-", - "C63134-", - "A63135-", - "G63136-", - "G63137-", - "A63138-", - "T63139-", - "C63140-", - "A63141-", - "T63142-", - "G63154-", - "T63155-", - "T63156-", - "A63157-", - "A63158-", - "C63159-", - "C63160-", - "A63161-", - "A63162-", - "C63163-", - "C63164-", - "G63165-", - "A63166-", - "A63174-", - "A63175-", - "A63176-", - "A63177-", - "T63178-", - "A63179-", - "A63180-", - "A63181-", - "T63182-", - "A63183-", - "T63184-", - "C63185-", - "A63186-", - "T63187-", - "T63188-", - "A63189-", - "A63190-", - "T63191-", - "A63192-", - "T63193-", - "A63194-", - "T63195-", - "G63196-", - "C63197-", - "T63198-", - "C63199-", - "T63200-", - "A63201-", - "G63202-", - "A63203-", - "T63204-", - "A63205-", - "T63206-", - "T63207-", - "A63208-", - "G63209-", - "T63210-", - "A63211-", - "T63212-", - "T63213-", - "T63214-", - "T63215-", - "T63216-", - "A63217-", - "T63218-", - "T63219-", - "A63220-", - "A63221-", - "T63222-", - "C63223-", - "C63224-", - "T63225-", - "T63226-", - "T63227-", - "G63228-", - "A63229-", - "T63230-", - "T63231-", - "A63232-", - "T63233-", - "C63234-", - "A63235-", - "T63236-", - "C63237-", - "T63238-", - "C63248-", - "G63249-", - "A63250-", - "A63251-", - "T63252-", - "G63253-", - "A63254-", - "T63286-", - "C63287-", - "C63288-", - "G63289-", - "G63290-", - "A63291-", - "G63292-", - "T63293-", - "A63294-", - "T63295-", - "T63296-", - "A63297-", - "A63298-", - "T63299-", - "G63300-", - "G63301-", - "G63302-", - "T63303-", - "T63304-", - "T63305-", - "A63306-", - "G63307-", - "T63308-", - "A63309-", - "A63310-", - "C63316-", - "C63317-", - "A63318-", - "T63319-", - "C63320-", - "G63321-", - "T63322-", - "T63323-", - "G63324-", - "C63325-", - "A63326-", - "A63327-", - "A63332-", - "A63333-", - "A63334-", - "A63335-", - "G63336-", - "T63337-", - "T63338-", - "G63339-", - "T63340-", - "C63341-", - "C63342-", - "A63343-", - "A63344-", - "G63345-", - "T63346-", - "A63349-", - "A63350-", - "G63351-", - "G63352-", - "A63353-", - "T63354-", - "A63355-", - "T63356-", - "T63357-", - "A63358-", - "T63359-", - "G63360-", - "C63361-", - "A63362-", - "T63363-", - "T63364-", - "A63372-", - "G63373-", - "A63374-", - "T63375-", - "A63376-", - "T63377-", - "C63378-", - "A63379-", - "C63380-", - "C63381-", - "T63382-", - "C63383-", - "A63384-", - "G63457-", - "T63458-", - "C63459-", - "T63460-", - "A63461-", - "C63462-", - "T63463-", - "A63464-", - "T63465-", - "T63466-", - "C63467-", - "T63468-", - "A63469-", - "T63470-", - "T63471-", - "T63472-", - "A63473-", - "A63474-", - "T63475-", - "T63476-", - "T63477-", - "T63478-", - "G63479-", - "T63480-", - "A63481-", - "G63482-", - "T63483-", - "T63484-", - "A63485-", - "A63486-", - "T63487-", - "T63488-", - "T63489-", - "A63490-", - "T63491-", - "C63492-", - "C89166T" - ], - "OPG081": [ - "M1-", - "V2-", - "D3-", - "A4-", - "I5-", - "T6-", - "V7-", - "X8-", - "X10-", - "I11-", - "C12-", - "I13-", - "T14-", - "V15-", - "L16-", - "M17-", - "L18-", - "L19-", - "M20-", - "V21-", - "I22-", - "S23-", - "G24-", - "T25-", - "A26-", - "M27-", - "I28-", - "V29-", - "K30-", - "E31-", - "L32-", - "N33-", - "P34-", - "N35-", - "D36-", - "I37-", - "F38-", - "T39-", - "M40-", - "Q41X", - "N46X", - "R47-", - "T48-", - "V49-", - "T50-", - "I51-", - "F52-", - "K53-", - "Y54-", - "I55-", - "G56-", - "L57-", - "F58-", - "I59-", - "Y60-" - ], - "OPG082": [ - "X23-", - "E24-", - "V25-", - "I26-", - "S27-", - "X30-", - "C31-", - "I32-", - "I33-", - "S34-", - "X35-", - "X36-", - "L37-", - "D38-", - "N39-", - "F40-", - "X41-", - "X42-", - "C43-", - "N44-", - "D45-", - "X46-", - "X48-", - "T49-", - "K50-", - "P51-", - "I52-", - "N53-", - "T54-", - "P55-", - "X56-", - "S67-", - "F68-", - "X69-", - "X72-", - "M73-", - "I74-", - "I75-", - "K76-", - "G77-", - "L78-", - "I79-", - "K80-", - "I81-", - "L82-", - "I83-", - "S84-", - "R85-", - "A86-", - "Y87-", - "I88-", - "N89-", - "D90-", - "I91-", - "Y92-", - "F93-", - "X96-", - "G97-", - "W98-", - "L99-", - "X100-", - "X104-", - "D105-", - "P106-", - "E107-", - "T108-", - "H109-", - "V110-", - "V111-", - "I112-", - "K113-", - "I114-", - "I115-", - "F116-", - "S118-", - "S119-", - "L120-", - "I121-", - "S122-", - "V127-", - "I128-", - "E129-", - "Y130-", - "L131-", - "K132-", - "P133-", - "Y134-", - "N135-", - "V136-", - "X137-", - "N138-", - "L139-", - "S140-", - "X141-", - "X144-", - "E145-", - "K146-", - "E147-", - "L148-", - "S149-", - "I150-", - "N151-", - "T152-", - "F153-", - "X154-", - "X158-", - "I159-", - "P160-", - "I161-", - "X162-", - "X163-", - "I164-", - "S165-", - "F166-", - "F167-", - "P168-", - "X169-", - "T171-", - "D172-", - "F173-", - "X174-", - "L175-", - "V176-", - "I177-", - "L178-", - "F179-", - "F180-", - "C188-", - "G189-", - "I190-", - "S191-", - "Y192-", - "I193-", - "S194-", - "X195-", - "X200-", - "Y201-", - "I202-", - "I203-", - "E204-", - "I205-", - "L206-", - "K207-", - "P208-", - "L209-", - "V210-", - "X211-", - "X212-", - "I213-", - "N214-", - "M215-", - "X216-", - "X232-", - "S233-", - "V234-", - "K235-", - "K236-", - "F237-", - "P238-", - "T239-", - "N240-", - "T241-", - "L242-", - "T243-", - "S244-", - "I245-", - "C246-", - "E247-", - "I248-", - "V249-", - "Y250-", - "S251-", - "F252-", - "D253-", - "E254-", - "K275X", - "X277-", - "S278-", - "L279-", - "L280-", - "D281-", - "L282-", - "P283-", - "S284-", - "X285-", - "V286-", - "E287-", - "I288-", - "K289-", - "A290-", - "I291-", - "X292-", - "G295-", - "V296-", - "D297-", - "F298-", - "I299-", - "X300-", - "X301-", - "I302-", - "N303-", - "N304-", - "K305-", - "R306-", - "X307-", - "T308-", - "T309-", - "I310-", - "L311-", - "V312-", - "I313-", - "A314-", - "K315-", - "D316-", - "N317-", - "F318-", - "L319-", - "K320-", - "N321-", - "S322-", - "T323-", - "F324-", - "S325-", - "G326-", - "T327-", - "F328-", - "I329-", - "K330-", - "E331-", - "N332-", - "I333-", - "I334-", - "W335-", - "K336-", - "G337-", - "I338-", - "X341-", - "R342-", - "I343-", - "I344-", - "K345-", - "S346-", - "X350-", - "P351-", - "T352-", - "I353-", - "K354-", - "S355-", - "V356-", - "T357-", - "N358-", - "X359-", - "I362-", - "C363-", - "K364X", - "K365-", - "H366X", - "C367-", - "F368-", - "X369-", - "T377-", - "L378-", - "S379-", - "H380-", - "I381-", - "X383-" - ], - "OPG083": [ - "D409-", - "K410-", - "L411-", - "T412-", - "T413-", - "K414-", - "L415-", - "N416-", - "R417-", - "I418-", - "V419-", - "D420-" - ] - }, - "labels": { - "aa": "OPG081: M1-, V2-, D3-, A4-, I5-, T6-, V7-, X8-, X10-, I11-, C12-, I13-, T14-, V15-, L16-, M17-, L18-, L19-, M20-, V21-, I22-, S23-, G24-, T25-, A26-, M27-, I28-, V29-, K30-, E31-, L32-, N33-, P34-, N35-, D36-, I37-, F38-, T39-, M40-, Q41X, N46X, R47-, T48-, V49-, T50-, I51-, F52-, K53-, Y54-, I55-, G56-, L57-, F58-, I59-, Y60-; OPG082: X23-, E24-, V25-, I26-, S27-, X30-, C31-, I32-, I33-, S34-, X35-, X36-, L37-, D38-, N39-, F40-, X41-, X42-, C43-, N44-, D45-, X46-, X48-, T49-, K50-, P51-, I52-, N53-, T54-, P55-, X56-, S67-, F68-, X69-, X72-, M73-, I74-, I75-, K76-, G77-, L78-, I79-, K80-, I81-, L82-, I83-, S84-, R85-, A86-, Y87-, I88-, N89-, D90-, I91-, Y92-, F93-, X96-, G97-, W98-, L99-, X100-, X104-, D105-, P106-, E107-, T108-, H109-, V110-, V111-, I112-, K113-, I114-, I115-, F116-, S118-, S119-, L120-, I121-, S122-, V127-, I128-, E129-, Y130-, L131-, K132-, P133-, Y134-, N135-, V136-, X137-, N138-, L139-, S140-, X141-, X144-, E145-, K146-, E147-, L148-, S149-, I150-, N151-, T152-, F153-, X154-, X158-, I159-, P160-, I161-, X162-, X163-, I164-, S165-, F166-, F167-, P168-, X169-, T171-, D172-, F173-, X174-, L175-, V176-, I177-, L178-, F179-, F180-, C188-, G189-, I190-, S191-, Y192-, I193-, S194-, X195-, X200-, Y201-, I202-, I203-, E204-, I205-, L206-, K207-, P208-, L209-, V210-, X211-, X212-, I213-, N214-, M215-, X216-, X232-, S233-, V234-, K235-, K236-, F237-, P238-, T239-, N240-, T241-, L242-, T243-, S244-, I245-, C246-, E247-, I248-, V249-, Y250-, S251-, F252-, D253-, E254-, K275X, X277-, S278-, L279-, L280-, D281-, L282-, P283-, S284-, X285-, V286-, E287-, I288-, K289-, A290-, I291-, X292-, G295-, V296-, D297-, F298-, I299-, X300-, X301-, I302-, N303-, N304-, K305-, R306-, X307-, T308-, T309-, I310-, L311-, V312-, I313-, A314-, K315-, D316-, N317-, F318-, L319-, K320-, N321-, S322-, T323-, F324-, S325-, G326-, T327-, F328-, I329-, K330-, E331-, N332-, I333-, I334-, W335-, K336-, G337-, I338-, X341-, R342-, I343-, I344-, K345-, S346-, X350-, P351-, T352-, I353-, K354-, S355-, V356-, T357-, N358-, X359-, I362-, C363-, K364X, K365-, H366X, C367-, F368-, X369-, T377-, L378-, S379-, H380-, I381-, X383-; OPG083: D409-, K410-, L411-, T412-, T413-, K414-, L415-, N416-, R417-, I418-, V419-, D420-" - } - }, - "children": [ - { - "name": "02112022_anal", - "node_attrs": { - "div": 2, - "author": { - "author": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K.", - "value": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K." - }, - "strain_original": { - "value": "02112022_anal" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ672570" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-02" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G62357-", - "C62361-", - "T62362-", - "T62371-" - ], - "OPG082": [ - "X361-", - "X364-", - "X366-" - ] - }, - "labels": { - "aa": "OPG082: X361-, X364-, X366-" - } - } - }, - { - "name": "NODE_0000037", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A2611-", - "C2612-", - "A2613-", - "C2614-", - "G2615-", - "A2616-", - "T2617-", - "A2618-", - "G2619-", - "A2620-", - "C2621-", - "A2622-", - "A2623-", - "C2624-", - "A2625-", - "T2626-", - "A2627-", - "G2628-", - "A2629-", - "T2630-", - "T2631-", - "A2632-", - "C2633-", - "G2634-", - "G2635-", - "C2636-", - "T2637-", - "T2638-", - "C2639-", - "T2640-", - "-62372T", - "-62374T", - "-62375T", - "A178815-", - "A178817-", - "A178819-", - "A178820-", - "A178821-", - "C178823-", - "A178824-", - "G178825-", - "A178826-", - "T178827-", - "T178828-", - "G178829-", - "T178830-", - "C178831-", - "G187391A", - "A194549-", - "A194550-", - "G194551-", - "T194552-", - "G194553-", - "T194554-", - "A194555-", - "A194556-", - "A194557-", - "G194558-", - "A194559-", - "C194560-", - "A194561-", - "A194562-", - "C194563-", - "G194564-", - "A194565-", - "A194566-", - "T194567-", - "A194568-", - "C194569-", - "A194570-", - "G194571-", - "A194572-", - "A194573-", - "G194574-", - "C194575-", - "C194576-", - "G194577-", - "T194578-", - "A194579-", - "A194580-", - "T194581-", - "C194582-", - "T194583-", - "A194584-", - "T194585-" - ], - "OPG002": [ - "K31-", - "C32-", - "K33-", - "D34-", - "N35-", - "E36-", - "Y37-", - "R38-", - "S39-", - "R40-", - "N41-", - "L42-", - "C43X", - "*350X" - ], - "OPG082": [ - "-360X" - ] - }, - "labels": { - "aa": "OPG002: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43X, *350X; OPG082: -360X" - } - }, - "children": [ - { - "name": "26012023_anal", - "node_attrs": { - "div": 3, - "author": { - "author": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K.", - "value": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K." - }, - "strain_original": { - "value": "26012023_anal" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ672572" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-01-26" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-47741A", - "-49679G", - "-49707A", - "-62106A", - "-62107T", - "-62108A", - "-62109G", - "-62110A", - "-62111T", - "-62112A", - "-62113A", - "-62114A", - "-62115G", - "-62116A", - "-62117G", - "-62118T", - "-62119C", - "-62120C", - "-62121T", - "-62122A", - "-62123T", - "-62124A", - "-62125T", - "-62126A", - "-62127T", - "-62128T", - "-62129T", - "-62130G", - "-62131A", - "-62132A", - "-62133A", - "-62134A", - "-62135T", - "-62136C", - "-62137G", - "-62138T", - "-62139T", - "-62140A", - "-62141C", - "-62142G", - "-62143G", - "-62144T", - "-62145T", - "-62146C", - "-62147G", - "-62148A", - "-62164T", - "-62165G", - "-62166C", - "-62167A", - "-62168T", - "-62169T", - "-62170G", - "-62171T", - "-62172G", - "-62173A", - "-62174A", - "-62175T", - "-62176A", - "-62177T", - "-62178A", - "-62179T", - "-62180C", - "-62181A", - "-62182T", - "-62183T", - "-62184A", - "-62185G", - "-62186G", - "-62187A", - "-62188T", - "-62189T", - "-62190T", - "-62191A", - "-62192A", - "-62193C", - "-62194T", - "-62195C", - "-62196C", - "-62197T", - "-62198T", - "-62199G", - "-62200A", - "-62201C", - "-62202T", - "-62203A", - "-62204T", - "-62205C", - "-62206A", - "-62207T", - "-62208G", - "-62209G", - "-62210C", - "-62211G", - "-62212G", - "-62213T", - "-62214G", - "-62215C", - "-62216C", - "-62217A", - "-62218G", - "-62219A", - "-62220A", - "-62221A", - "-62222T", - "-62223T", - "-62224A", - "-62225C", - "-62226C", - "-62227A", - "-62228T", - "-62229C", - "-62230A", - "-62231A", - "-62232A", - "-62233A", - "-62234G", - "-62235C", - "-62236A", - "-62237T", - "-62238T", - "-62239A", - "-62240A", - "-62241T", - "-62242A", - "-62243C", - "-62244A", - "-62245G", - "-62246T", - "-62247T", - "-62248A", - "-62249T", - "-62250G", - "-62251C", - "-62252A", - "-62253G", - "-62254A", - "-62255T", - "-62256C", - "-62257G", - "-62258C", - "-62259A", - "-62260G", - "-62261T", - "-62262T", - "-62263A", - "-62264G", - "-62265A", - "-62266A", - "-62267C", - "-62268G", - "-62269G", - "-62270T", - "-62271T", - "-62272A", - "-62273T", - "-62274A", - "-62275G", - "-62276C", - "-62277A", - "-62278T", - "-62279C", - "-62280C", - "-62281A", - "-62282C", - "-62283C", - "-62284A", - "-62285T", - "-62286T", - "-62287T", - "-62288A", - "-62289T", - "-62290A", - "-62291T", - "-62292C", - "-62293T", - "-62294A", - "-62295A", - "-62296A", - "-62297A", - "-62298A", - "-62299T", - "-62300T", - "-62301A", - "-62302G", - "-62303A", - "-62304T", - "-62305C", - "-62306A", - "-62307A", - "-62308A", - "-62309G", - "-62310A", - "-62311A", - "-62312T", - "-62313A", - "-62314T", - "-62315G", - "-62316T", - "-62317G", - "-62318A", - "-62319C", - "-62320A", - "-62321A", - "-62322C", - "-62323G", - "-62324T", - "-62325C", - "-62326C", - "-62327T", - "-62328A", - "-62329G", - "-62330T", - "-62331T", - "-62332G", - "-62333T", - "-62334A", - "-62335T", - "-62336A", - "-62337C", - "-62338T", - "-62339G", - "-62340A", - "-62341G", - "-62342A", - "-62343A", - "-62344T", - "-62345T", - "-62346G", - "-62347A", - "-62348C", - "-62349G", - "-62350A", - "-62351A", - "-62352A", - "-62353C", - "-62354A", - "-62355A", - "-62356T", - "-62358T", - "-62359T", - "-62360T", - "-62363T", - "-62364A", - "-62365C", - "-62366A", - "-62367T", - "-62368A", - "-62369T", - "-62370T", - "-62373T", - "-62376C", - "-62377T", - "-62378T", - "-62379A", - "-62380T", - "-62381T", - "-62382A", - "-62383G", - "-62384T", - "-62385A", - "-62386A", - "-62387C", - "-62388C", - "-62389G", - "-62390A", - "-62391C", - "-62392T", - "-62393T", - "-62394A", - "-62395A", - "-62396T", - "-62397A", - "-62398G", - "-62399T", - "-62400A", - "-62401G", - "-62402G", - "-62403A", - "-62404A", - "-62405C", - "-62406T", - "-62407G", - "-62408G", - "-62409A", - "-62410A", - "-62411A", - "-62412A", - "-62413C", - "-62414T", - "-62415A", - "-62416G", - "-62417A", - "-62418C", - "-62419T", - "-62420T", - "-62421G", - "-62422A", - "-62423T", - "-62424T", - "-62425A", - "-62426T", - "-62427T", - "-62428C", - "-62429T", - "-62430A", - "-62431T", - "-62432A", - "-62433A", - "-62434G", - "-62435T", - "-62436A", - "-62437T", - "-62438A", - "-62439G", - "-62440A", - "-62441T", - "-62442A", - "-62443C", - "-62444C", - "-62445C", - "-62446T", - "-62447T", - "-62448C", - "-62449C", - "-62450A", - "-62451A", - "-62452A", - "-62453T", - "-62454A", - "-62455A", - "-62456T", - "-62457G", - "-62458T", - "-62459T", - "-62460C", - "-62461T", - "-62462C", - "-62463T", - "-62464T", - "-62465T", - "-62466G", - "-62467A", - "-62468T", - "-62469A", - "-62470A", - "-62471A", - "-62472A", - "-62473G", - "-62474T", - "-62475T", - "-62476C", - "-62477C", - "-62478A", - "-62479G", - "-62480A", - "-62481A", - "-62482A", - "-62483A", - "-62484T", - "-62485G", - "-62486T", - "-62487A", - "-62488G", - "-62489A", - "-62490A", - "-62491T", - "-62492T", - "-62493T", - "-62494T", - "-62495T", - "-62496T", - "-62497A", - "-62498A", - "-62499A", - "-62500A", - "-62501A", - "-62502G", - "-62503T", - "-62504T", - "-62505A", - "-62506T", - "-62507C", - "-62508T", - "-62509T", - "-62510T", - "-62511T", - "-62512G", - "-62513C", - "-62514T", - "-62515A", - "-62516T", - "-62517T", - "-62518A", - "-62519C", - "-62520T", - "-62521A", - "-62522A", - "-62523T", - "-62524A", - "-62525T", - "-62526C", - "-62527G", - "-62528T", - "-62529G", - "-62530G", - "-62531T", - "-62532T", - "-62533A", - "-62534G", - "-62535A", - "-62536C", - "-62537G", - "-62538C", - "-62539T", - "-62540T", - "-62541A", - "-62542T", - "-62543T", - "-62544A", - "-62545T", - "-62546T", - "-62547A", - "-62548A", - "-62549T", - "-62550A", - "-62551T", - "-62552G", - "-62553A", - "-62554G", - "-62555T", - "-62556G", - "-62557A", - "-62558T", - "-62559G", - "-62560A", - "-62561A", - "-62562A", - "-62563T", - "-62564C", - "-62565C", - "-62566A", - "-62567C", - "-62568A", - "-62569C", - "-62570C", - "-62571G", - "-62572C", - "-62573T", - "-62574T", - "-62575C", - "-62576T", - "-62577A", - "-62578G", - "-62579A", - "-62580T", - "-62581A", - "-62582T", - "-62583C", - "-62584G", - "-62585C", - "-62586T", - "-62587T", - "-62588T", - "-62589T", - "-62590A", - "-62591T", - "-62592T", - "-62593T", - "-62594C", - "-62595C", - "-62596A", - "-62597C", - "-62598A", - "-62599T", - "-62600T", - "-62601A", - "-62602G", - "-62603A", - "-62604T", - "-62605G", - "-62606G", - "-62607T", - "-62608A", - "-62609A", - "-62610A", - "-62611T", - "-62612C", - "-62613C", - "-62614A", - "-62615A", - "-62616T", - "-62617A", - "-62618G", - "-62619T", - "-62620G", - "-62621A", - "-62622A", - "-62623A", - "-62624C", - "-62625T", - "-62626A", - "-62627T", - "-62628C", - "-62691T", - "-62692T", - "-62693C", - "-62694G", - "-62695T", - "-62696C", - "-62697A", - "-62698A", - "-62699A", - "-62700T", - "-62701G", - "-62702A", - "-62703A", - "-62704T", - "-62705A", - "-62706A", - "-62707A", - "-62708C", - "-62709A", - "-62710A", - "-62711T", - "-62712T", - "-62713T", - "-62714C", - "-62715A", - "-62716C", - "-62717A", - "-62718A", - "-62719A", - "-62720T", - "-62721G", - "-62722G", - "-62723A", - "-62724T", - "-62725G", - "-62726T", - "-62727T", - "-62728A", - "-62729A", - "-62730T", - "-62731G", - "-62732T", - "-62733A", - "-62734T", - "-62735T", - "-62736A", - "-62737G", - "-62738T", - "-62739A", - "-62740G", - "-62741G", - "-62742A", - "-62743A", - "-62744A", - "-62745T", - "-62746T", - "-62747T", - "-62748T", - "-62749T", - "-62750T", - "-62751G", - "-62752A", - "-62753C", - "-62754G", - "-62755C", - "-62756T", - "-62757A", - "-62758G", - "-62759T", - "-62760G", - "-62761G", - "-62762A", - "-62763A", - "-62764T", - "-62765T", - "-62766G", - "-62767A", - "-62768A", - "-62769G", - "-62770A", - "-62771T", - "-62772T", - "-62773C", - "-62774T", - "-62775A", - "-62776A", - "-62777T", - "-62778G", - "-62779G", - "-62780A", - "-62781T", - "-62782G", - "-62783A", - "-62784T", - "-62785G", - "-62786T", - "-62787T", - "-62788C", - "-62789T", - "-62790A", - "-62791C", - "-62792C", - "-62793T", - "-62794A", - "-62795T", - "-62796T", - "-62797T", - "-62798C", - "-62799A", - "-62800T", - "-62801C", - "-62802C", - "-62803G", - "-62804A", - "-62805T", - "-62806A", - "-62807A", - "-62808C", - "-62809A", - "-62810T", - "-62811G", - "-62812T", - "-62813T", - "-62814A", - "-62815A", - "-62816T", - "-62817T", - "-62818T", - "-62819C", - "-62820C", - "-62821A", - "-62822A", - "-62823T", - "-62824A", - "-62825C", - "-62826C", - "-62827A", - "-62828A", - "-62829C", - "-62830G", - "-62831G", - "-62832T", - "-62833T", - "-62834T", - "-62835T", - "-62836A", - "-62837A", - "-62838T", - "-62839A", - "-62840T", - "-62841T", - "-62842T", - "-62843C", - "-62844G", - "-62845A", - "-62846T", - "-62847G", - "-62848A", - "-62849T", - "-62850A", - "-62851T", - "-62852A", - "-62853C", - "-62854G", - "-62855G", - "-62856T", - "-62857A", - "-62858G", - "-62859T", - "-62860C", - "-62861T", - "-62862C", - "-62863T", - "-62864C", - "-62865T", - "-62866T", - "-62867T", - "-62868C", - "-62869G", - "-62870G", - "-62871A", - "-62872C", - "-62873T", - "-62874T", - "-62875A", - "-62876T", - "-62877A", - "-62878T", - "-62879A", - "-62880G", - "-62881C", - "-62882T", - "-62883T", - "-62884A", - "-62885T", - "-62886T", - "-62887C", - "-62888C", - "-62889A", - "-62890C", - "-62891A", - "-62892A", - "-62893T", - "-62894A", - "-62895C", - "-62896G", - "-62897A", - "-62898G", - "-62899T", - "-62900C", - "-62901A", - "-62902T", - "-62903T", - "-62904A", - "-62905T", - "-62906A", - "-62907T", - "-62908A", - "-62909C", - "-62910T", - "-62911C", - "-62912C", - "-62913A", - "-62914A", - "-62915A", - "-62916A", - "-62917A", - "-62918A", - "-62919C", - "-62920A", - "-62921A", - "-62922A", - "-62923A", - "-62924T", - "-62925A", - "-62926A", - "-62927C", - "-62928T", - "-62929A", - "-62930G", - "-62931T", - "-62932A", - "-62933T", - "-62934A", - "-62935A", - "-62936A", - "-62937A", - "-62938T", - "-62939C", - "-62940T", - "-62941G", - "-62942T", - "-62943A", - "-62944T", - "-62945C", - "-62946G", - "-62947A", - "-62948A", - "-62949T", - "-62950G", - "-62951G", - "-62952G", - "-62953A", - "-62954A", - "-62955A", - "-62956A", - "-62957A", - "-62958C", - "-62959G", - "-62960A", - "-62961A", - "-62962A", - "-62963T", - "-62964T", - "-62965A", - "-62966T", - "-62967C", - "-62968G", - "-62969A", - "-62970T", - "-62971A", - "-62972T", - "-62973A", - "-62974G", - "-62975G", - "-62976T", - "-62977A", - "-62978T", - "-62979A", - "-62980G", - "-62981A", - "-62982A", - "-62983T", - "-62984C", - "-62985C", - "-62986G", - "-62987G", - "-62988A", - "-62989A", - "-62990C", - "-62991A", - "-62992T", - "-62993T", - "-62994G", - "-62995A", - "-62996A", - "-62997C", - "-62998G", - "-62999T", - "-63000A", - "-63001T", - "-63002T", - "-63003A", - "-63004A", - "-63005T", - "-63006A", - "-63007C", - "-63008T", - "-63009T", - "-63010A", - "-63011A", - "-63012T", - "-63013T", - "-63014C", - "-63015T", - "-63016T", - "-63017T", - "-63018T", - "-63019T", - "-63020C", - "-63021A", - "-63022G", - "-63023T", - "-63024G", - "-63025G", - "-63026T", - "-63027A", - "-63028A", - "-63029G", - "-63030A", - "-63031A", - "-63032C", - "-63033C", - "-63034G", - "-63035A", - "-63036T", - "-63037A", - "-63038G", - "-63039G", - "-63040T", - "-63041T", - "-63042A", - "-63043T", - "-63044T", - "-63045G", - "-63046A", - "-63047C", - "-63048A", - "-63049T", - "-63050T", - "-63051G", - "-63052T", - "-63053A", - "-63054T", - "-63055G", - "-63056G", - "-63057T", - "-63058T", - "-63059T", - "-63060T", - "-63061A", - "-63062A", - "-63063A", - "-63064T", - "-63065A", - "-63066T", - "-63067T", - "-63068C", - "-63069T", - "-63070A", - "-63071T", - "-63072A", - "-63073A", - "-63074C", - "-63075T", - "-63076T", - "-63077G", - "-63078A", - "-63079G", - "-63080A", - "-63081C", - "-63082T", - "-63083T", - "-63084G", - "-63085A", - "-63086T", - "-63087A", - "-63088G", - "-63089A", - "-63090T", - "-63091A", - "-63092T", - "-63093T", - "-63094A", - "-63095A", - "-63096T", - "-63097G", - "-63098A", - "-63099C", - "-63100G", - "-63101A", - "-63102A", - "-63103T", - "-63104T", - "-63105G", - "-63106A", - "-63107A", - "-63108A", - "-63109A", - "-63110T", - "-63111T", - "-63112A", - "-63113T", - "-63114T", - "-63115T", - "-63116T", - "-63117T", - "-63118A", - "-63119T", - "-63120C", - "-63121A", - "-63122C", - "-63123C", - "-63124A", - "-63125C", - "-63126G", - "-63127T", - "-63128G", - "-63129T", - "-63130G", - "-63131T", - "-63132T", - "-63133T", - "-63134C", - "-63135A", - "-63136G", - "-63137G", - "-63138A", - "-63139T", - "-63140C", - "-63141A", - "-63142T", - "-63143C", - "-63144G", - "-63145T", - "-63146C", - "-63147G", - "-63148A", - "-63149C", - "-63150G", - "-63151C", - "-63152C", - "-63153A", - "-63154G", - "-63155T", - "-63156T", - "-63157A", - "-63158A", - "-63159C", - "-63160C", - "-63161A", - "-63162A", - "-63163C", - "-63164C", - "-63165G", - "-63166A", - "-63167A", - "-63168T", - "-63169G", - "-63170G", - "-63171A", - "-63172G", - "-63173T", - "-63174A", - "-63175A", - "-63176A", - "-63177A", - "-63178T", - "-63179A", - "-63180A", - "-63181A", - "-63182T", - "-63183A", - "-63184T", - "-63185C", - "-63186A", - "-63187T", - "-63188T", - "-63189A", - "-63190A", - "-63191T", - "-63192A", - "-63193T", - "-63194A", - "-63195T", - "-63196G", - "-63197C", - "-63198T", - "-63199C", - "-63200T", - "-63201A", - "-63202G", - "-63203A", - "-63204T", - "-63205A", - "-63206T", - "-63207T", - "-63208A", - "-63209G", - "-63210T", - "-63211A", - "-63212T", - "-63213T", - "-63214T", - "-63215T", - "-63216T", - "-63217A", - "-63218T", - "-63219T", - "-63220A", - "-63221A", - "-63222T", - "-63223C", - "-63224C", - "-63225T", - "-63226T", - "-63227T", - "-63228G", - "-63229A", - "-63230T", - "-63231T", - "-63232A", - "-63233T", - "-63234C", - "-63235A", - "-63236T", - "-63237C", - "-63238T", - "-63239T", - "-63240C", - "-63241T", - "-63242C", - "-63243G", - "-63244T", - "-63245A", - "-63246C", - "-63247G", - "-63248C", - "-63249G", - "-63250A", - "-63251A", - "-63252T", - "-63253G", - "-63254A", - "-63255T", - "-63256T", - "-63257C", - "-63258C", - "-63259A", - "-63260T", - "-63261G", - "-63262A", - "-63263T", - "-63264C", - "-63265A", - "-63266A", - "-63267G", - "-63268A", - "-63269G", - "-63270T", - "-63271G", - "-63272A", - "-63273T", - "-63274T", - "-63275T", - "-63276G", - "-63277A", - "-63278G", - "-63279A", - "-63280A", - "-63281C", - "-63282A", - "-63283T", - "-63284C", - "-63285C", - "-63286T", - "-63287C", - "-63288C", - "-63289G", - "-63290G", - "-63291A", - "-63292G", - "-63293T", - "-63294A", - "-63295T", - "-63296T", - "-63297A", - "-63298A", - "-63299T", - "-63300G", - "-63301G", - "-63302G", - "-63303T", - "-63304T", - "-63305T", - "-63306A", - "-63307G", - "-63308T", - "-63309A", - "-63310A", - "-63311A", - "-63312C", - "-63313A", - "-63314G", - "-63315T", - "-63316C", - "-63317C", - "-63318A", - "-63319T", - "-63320C", - "-63321G", - "-63322T", - "-63323T", - "-63324G", - "-63325C", - "-63326A", - "-63327A", - "-63328T", - "-63329A", - "-63330A", - "-63331T", - "-63332A", - "-63333A", - "-63334A", - "-63335A", - "-63336G", - "-63337T", - "-63338T", - "-63339G", - "-63340T", - "-63341C", - "-63342C", - "-63343A", - "-63344A", - "-63345G", - "-63346T", - "-63347T", - "-63348A", - "-63349A", - "-63350A", - "-63351G", - "-63352G", - "-63353A", - "-63354T", - "-63355A", - "-63356T", - "-63357T", - "-63358A", - "-63359T", - "-63360G", - "-63361C", - "-63362A", - "-63363T", - "-63364T", - "-63365C", - "-63366G", - "-63367T", - "-63368T", - "-63369T", - "-63370A", - "-63371A", - "-63372A", - "-63373G", - "-63374A", - "-63375T", - "-63376A", - "-63377T", - "-63378C", - "-63379A", - "-63380C", - "-63381C", - "-63382T", - "-63383C", - "-63384A", - "-63385T", - "-63386C", - "-63387T", - "-63388A", - "-63389A", - "-63390C", - "-63391G", - "-63392G", - "-63393A", - "-63394G", - "-63395A", - "-63396C", - "-63397A", - "-63398A", - "-63399T", - "-63400T", - "-63401T", - "-63402T", - "-63403T", - "-63404T", - "-63405G", - "-63406G", - "-63407T", - "-63408A", - "-63409G", - "-63410G", - "-63411T", - "-63412T", - "-63413T", - "-63414T", - "-63415A", - "-63416G", - "-63417A", - "-63418G", - "-63419A", - "-63420C", - "-63421T", - "-63422T", - "-63423T", - "-63424G", - "-63425A", - "-63426A", - "-63427G", - "-63428C", - "-63429T", - "-63430A", - "-63431C", - "-63432T", - "-63433T", - "-63434G", - "-63435T", - "-63436T", - "-63437T", - "-63438A", - "-63439A", - "-63440C", - "-63441A", - "-63442A", - "-63443A", - "-63444G", - "-63445T", - "-63446T", - "-63447A", - "-63448T", - "-63449T", - "-63450C", - "-63451A", - "-63452T", - "-63453C", - "-63454G", - "-63455T", - "-63456C", - "-63457G", - "-63458T", - "-63459C", - "-63460T", - "-63461A", - "-63462C", - "-63463T", - "-63464A", - "-63465T", - "-63466T", - "-63467C", - "-63468T", - "-63469A", - "-63470T", - "-63471T", - "-63472T", - "-63473A", - "-63474A", - "-63475T", - "-63476T", - "-63477T", - "-63478T", - "-63479G", - "-63480T", - "-63481A", - "-63482G", - "-63483T", - "-63484T", - "-63485A", - "-63486A", - "-63487T", - "-63488T", - "-63489T", - "-63490A", - "-63491T", - "-63492C", - "G178814-", - "C178816-", - "G178818-", - "G178822-" - ], - "OPG068": [ - "X493E", - "X503T", - "X568*" - ], - "OPG081": [ - "-1M", - "-2V", - "-3D", - "-4A", - "-5I", - "-6T", - "-7V", - "-8L", - "-9T", - "-10A", - "-11I", - "-12C", - "-13I", - "-14T", - "-15V", - "-16L", - "-17M", - "-18L", - "-19L", - "-20M", - "-21V", - "-22I", - "-23S", - "-24G", - "-25T", - "-26A", - "-27M", - "-28I", - "-29V", - "-30K", - "-31E", - "-32L", - "-33N", - "-34P", - "-35N", - "-36D", - "-37I", - "-38F", - "-39T", - "-40M", - "X41Q", - "X46N", - "-47R", - "-48T", - "-49V", - "-50T", - "-51I", - "-52F", - "-53K", - "-54Y", - "-55I", - "-56G", - "-57L", - "-58F", - "-59I", - "-60Y", - "X80*" - ], - "OPG082": [ - "-1M", - "-2N", - "-3N", - "-4F", - "-5V", - "-6K", - "-7Q", - "-8V", - "-9A", - "-10S", - "-11K", - "-12S", - "-13L", - "-14K", - "-15P", - "-16T", - "-17K", - "-18K", - "-19L", - "-20S", - "-21P", - "-22L", - "-23D", - "-24E", - "-25V", - "-26I", - "-27S", - "-28L", - "-29N", - "-30E", - "-31C", - "-32I", - "-33I", - "-34S", - "-35F", - "-36N", - "-37L", - "-38D", - "-39N", - "-40F", - "-41Y", - "-42Y", - "-43C", - "-44N", - "-45D", - "-46G", - "-47L", - "-48F", - "-49T", - "-50K", - "-51P", - "-52I", - "-53N", - "-54T", - "-55P", - "-56E", - "-57D", - "-58V", - "-59L", - "-60K", - "-61S", - "-62L", - "-63L", - "-64I", - "-65M", - "-66E", - "-67S", - "-68F", - "-69A", - "-70Y", - "-71E", - "-72K", - "-73M", - "-74I", - "-75I", - "-76K", - "-77G", - "-78L", - "-79I", - "-80K", - "-81I", - "-82L", - "-83I", - "-84S", - "-85R", - "-86A", - "-87Y", - "-88I", - "-89N", - "-90D", - "-91I", - "-92Y", - "-93F", - "-94T", - "-95P", - "-96F", - "-97G", - "-98W", - "-99L", - "-100T", - "-101G", - "-102V", - "-103D", - "-104D", - "-105D", - "-106P", - "-107E", - "-108T", - "-109H", - "-110V", - "-111V", - "-112I", - "-113K", - "-114I", - "-115I", - "-116F", - "-117N", - "-118S", - "-119S", - "-120L", - "-121I", - "-122S", - "-123I", - "-124K", - "-125S", - "-126Q", - "-127V", - "-128I", - "-129E", - "-130Y", - "-131L", - "-132K", - "-133P", - "-134Y", - "-135N", - "-136V", - "-137N", - "-138N", - "-139L", - "-140S", - "-141V", - "-142L", - "-143T", - "-144T", - "-145E", - "-146K", - "-147E", - "-148L", - "-149S", - "-150I", - "-151N", - "-152T", - "-153F", - "-154N", - "-155V", - "-156P", - "-157D", - "-158S", - "-159I", - "-160P", - "-161I", - "-162S", - "-163I", - "-164I", - "-165S", - "-166F", - "-167F", - "-168P", - "-169F", - "-170D", - "-171T", - "-172D", - "-173F", - "-174I", - "-175L", - "-176V", - "-177I", - "-178L", - "-179F", - "-180F", - "-181G", - "-182V", - "-183Y", - "-184N", - "-185D", - "-186S", - "-187Y", - "-188C", - "-189G", - "-190I", - "-191S", - "-192Y", - "-193I", - "-194S", - "-195P", - "-196K", - "-197E", - "-198R", - "-199L", - "-200P", - "-201Y", - "-202I", - "-203I", - "-204E", - "-205I", - "-206L", - "-207K", - "-208P", - "-209L", - "-210V", - "-211L", - "-212E", - "-213I", - "-214N", - "-215M", - "-216L", - "-217S", - "-218D", - "-219E", - "-220I", - "-221G", - "-222R", - "-223T", - "-224S", - "-225S", - "-226I", - "-227R", - "-228I", - "-229F", - "-230N", - "-231S", - "-232T", - "-233S", - "-234V", - "-235K", - "-236K", - "-237F", - "-238P", - "-239T", - "-240N", - "-241T", - "-242L", - "-243T", - "-244S", - "-245I", - "-246C", - "-247E", - "-248I", - "-249V", - "-250Y", - "-251S", - "-252F", - "-253D", - "-254E", - "X275K", - "-276I", - "-277V", - "-278S", - "-279L", - "-280L", - "-281D", - "-282L", - "-283P", - "-284S", - "-285N", - "-286V", - "-287E", - "-288I", - "-289K", - "-290A", - "-291I", - "-292S", - "-293R", - "-294S", - "-295G", - "-296V", - "-297D", - "-298F", - "-299I", - "-300T", - "-301H", - "-302I", - "-303N", - "-304N", - "-305K", - "-306R", - "-307L", - "-308T", - "-309T", - "-310I", - "-311L", - "-312V", - "-313I", - "-314A", - "-315K", - "-316D", - "-317N", - "-318F", - "-319L", - "-320K", - "-321N", - "-322S", - "-323T", - "-324F", - "-325S", - "-326G", - "-327T", - "-328F", - "-329I", - "-330K", - "-331E", - "-332N", - "-333I", - "-334I", - "-335W", - "-336K", - "-337G", - "-338I", - "-339Y", - "-340T", - "-341Y", - "-342R", - "-343I", - "-344I", - "-345K", - "-346S", - "-347S", - "-348F", - "-349P", - "-350V", - "-351P", - "-352T", - "-353I", - "-354K", - "-355S", - "-356V", - "-357T", - "-358N", - "-359K", - "X360K", - "X361K", - "-362I", - "-363C", - "X364K", - "-365K", - "X366H", - "-367C", - "-368F", - "-369V", - "-370N", - "-371S", - "-372Q", - "-373Y", - "-374T", - "-375T", - "-376R", - "-377T", - "-378L", - "-379S", - "-380H", - "-381I", - "-382L", - "-383*" - ], - "OPG083": [ - "-409D", - "-410K", - "-411L", - "-412T", - "-413T", - "-414K", - "-415L", - "-416N", - "-417R", - "-418I", - "-419V", - "-420D", - "-421D", - "-422D", - "-423E", - "-424*" - ] - }, - "labels": { - "aa": "OPG068: X493E, X503T, X568*; OPG081: -1M, -2V, -3D, -4A, -5I, -6T, -7V, -8L, -9T, -10A, -11I, -12C, -13I, -14T, -15V, -16L, -17M, -18L, -19L, -20M, -21V, -22I, -23S, -24G, -25T, -26A, -27M, -28I, -29V, -30K, -31E, -32L, -33N, -34P, -35N, -36D, -37I, -38F, -39T, -40M, X41Q, X46N, -47R, -48T, -49V, -50T, -51I, -52F, -53K, -54Y, -55I, -56G, -57L, -58F, -59I, -60Y, X80*; OPG082: -1M, -2N, -3N, -4F, -5V, -6K, -7Q, -8V, -9A, -10S, -11K, -12S, -13L, -14K, -15P, -16T, -17K, -18K, -19L, -20S, -21P, -22L, -23D, -24E, -25V, -26I, -27S, -28L, -29N, -30E, -31C, -32I, -33I, -34S, -35F, -36N, -37L, -38D, -39N, -40F, -41Y, -42Y, -43C, -44N, -45D, -46G, -47L, -48F, -49T, -50K, -51P, -52I, -53N, -54T, -55P, -56E, -57D, -58V, -59L, -60K, -61S, -62L, -63L, -64I, -65M, -66E, -67S, -68F, -69A, -70Y, -71E, -72K, -73M, -74I, -75I, -76K, -77G, -78L, -79I, -80K, -81I, -82L, -83I, -84S, -85R, -86A, -87Y, -88I, -89N, -90D, -91I, -92Y, -93F, -94T, -95P, -96F, -97G, -98W, -99L, -100T, -101G, -102V, -103D, -104D, -105D, -106P, -107E, -108T, -109H, -110V, -111V, -112I, -113K, -114I, -115I, -116F, -117N, -118S, -119S, -120L, -121I, -122S, -123I, -124K, -125S, -126Q, -127V, -128I, -129E, -130Y, -131L, -132K, -133P, -134Y, -135N, -136V, -137N, -138N, -139L, -140S, -141V, -142L, -143T, -144T, -145E, -146K, -147E, -148L, -149S, -150I, -151N, -152T, -153F, -154N, -155V, -156P, -157D, -158S, -159I, -160P, -161I, -162S, -163I, -164I, -165S, -166F, -167F, -168P, -169F, -170D, -171T, -172D, -173F, -174I, -175L, -176V, -177I, -178L, -179F, -180F, -181G, -182V, -183Y, -184N, -185D, -186S, -187Y, -188C, -189G, -190I, -191S, -192Y, -193I, -194S, -195P, -196K, -197E, -198R, -199L, -200P, -201Y, -202I, -203I, -204E, -205I, -206L, -207K, -208P, -209L, -210V, -211L, -212E, -213I, -214N, -215M, -216L, -217S, -218D, -219E, -220I, -221G, -222R, -223T, -224S, -225S, -226I, -227R, -228I, -229F, -230N, -231S, -232T, -233S, -234V, -235K, -236K, -237F, -238P, -239T, -240N, -241T, -242L, -243T, -244S, -245I, -246C, -247E, -248I, -249V, -250Y, -251S, -252F, -253D, -254E, X275K, -276I, -277V, -278S, -279L, -280L, -281D, -282L, -283P, -284S, -285N, -286V, -287E, -288I, -289K, -290A, -291I, -292S, -293R, -294S, -295G, -296V, -297D, -298F, -299I, -300T, -301H, -302I, -303N, -304N, -305K, -306R, -307L, -308T, -309T, -310I, -311L, -312V, -313I, -314A, -315K, -316D, -317N, -318F, -319L, -320K, -321N, -322S, -323T, -324F, -325S, -326G, -327T, -328F, -329I, -330K, -331E, -332N, -333I, -334I, -335W, -336K, -337G, -338I, -339Y, -340T, -341Y, -342R, -343I, -344I, -345K, -346S, -347S, -348F, -349P, -350V, -351P, -352T, -353I, -354K, -355S, -356V, -357T, -358N, -359K, X360K, X361K, -362I, -363C, X364K, -365K, X366H, -367C, -368F, -369V, -370N, -371S, -372Q, -373Y, -374T, -375T, -376R, -377T, -378L, -379S, -380H, -381I, -382L, -383*; OPG083: -409D, -410K, -411L, -412T, -413T, -414K, -415L, -416N, -417R, -418I, -419V, -420D, -421D, -422D, -423E, -424*" - } - } - }, - { - "name": "NODE_0000038", - "node_attrs": { - "div": 7, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G2641-", - "T2642-", - "A2643-", - "T2644-", - "T2645-", - "C2646-", - "G2647-", - "T2648-", - "T2649-", - "G2650-", - "T2651-", - "C2652-", - "T2653-", - "T2654-", - "T2655-", - "A2656-", - "C2657-", - "A2658-", - "C2659-", - "T2660-", - "T2661-", - "C8201T", - "T39397C", - "A47693-", - "C47694-", - "T47695-", - "C47696-", - "A47697-", - "T47698-", - "T47699-", - "A47700-", - "C47701-", - "G47702-", - "A47703-", - "G47704-", - "A47705-", - "C47706-", - "A47707-", - "T47708-", - "T47709-", - "G47710-", - "A47711-", - "A47712-", - "A47713-", - "C47714-", - "T47715-", - "A47716-", - "G47717-", - "G47718-", - "A47719-", - "T47720-", - "A47721-", - "T47722-", - "A47723-", - "T47724-", - "A47725-", - "A47726-", - "A47727-", - "A47728-", - "T47729-", - "T47730-", - "T47731-", - "A47732-", - "A47733-", - "G47734-", - "G47735-", - "G47736-", - "A47737-", - "A47738-", - "T47739-", - "G47740-", - "T47742-", - "T47743-", - "A47744-", - "G47745-", - "G47746-", - "A47747-", - "C47748-", - "T47749-", - "A47750-", - "C47751-", - "T47752-", - "A47753-", - "C47754-", - "T47755-", - "C47756-", - "T47757-", - "A47758-", - "G47759-", - "A47760-", - "A47761-", - "G47762-", - "A47763-", - "T47764-", - "A47765-", - "T47766-", - "A47767-", - "G47768-", - "C47769-", - "A47770-", - "C47771-", - "C47772-", - "A47773-", - "T47774-", - "C47775-", - "T47776-", - "A47777-", - "T47778-", - "T47779-", - "C47780-", - "C47781-", - "A47782-", - "A47783-", - "A47784-", - "T47785-", - "A47786-", - "A47787-", - "T47788-", - "C47789-", - "A47790-", - "G47791-", - "A47792-", - "A47793-", - "A47794-", - "A47795-", - "C47796-", - "T47797-", - "T47798-", - "A47799-", - "T47800-", - "A47801-", - "A47802-", - "A47803-", - "C47804-", - "T47805-", - "A47806-", - "T47807-", - "T47808-", - "C47809-", - "T47810-", - "C47811-", - "G47812-", - "G47813-", - "A47814-", - "C47815-", - "A47816-", - "T47817-", - "T47818-", - "T47819-", - "C47820-", - "A47821-", - "G47822-", - "T47823-", - "C47824-", - "A47825-", - "T47826-", - "T47827-", - "G47828-", - "G47829-", - "C47830-", - "A47831-", - "A47832-", - "A47833-", - "G47834-", - "C47835-", - "A47836-", - "T47837-", - "C47838-", - "A47839-", - "C47840-", - "A47841-", - "G47842-", - "A47843-", - "A47844-", - "T47845-", - "C47846-", - "C47847-", - "G47848-", - "A47849-", - "G47850-", - "T47851-", - "A47852-", - "A47853-", - "G47854-", - "A47855-", - "T47856-", - "G47857-", - "A47858-", - "T47859-", - "A47860-", - "T47861-", - "A47862-", - "T47863-", - "G47864-", - "C47865-", - "T47866-", - "C47867-", - "G47868-", - "C47869-", - "T47870-", - "G47871-", - "C47872-", - "T47873-", - "T47874-", - "T47875-", - "A47876-", - "C47877-", - "A47878-", - "T47879-", - "G47880-", - "T47881-", - "T47882-", - "T47883-", - "C47884-", - "C47885-", - "C47886-", - "A47887-", - "A47888-", - "T47889-", - "T47890-", - "T47891-", - "G47892-", - "T47893-", - "T47894-", - "T47895-", - "G47896-", - "G47897-", - "A47898-", - "G47899-", - "A47900-", - "T47901-", - "G47902-", - "A47903-", - "C47904-", - "C47905-", - "A47906-", - "T47907-", - "A47908-", - "G47909-", - "A47910-", - "T47911-", - "T47912-", - "C47913-", - "A47914-", - "T47915-", - "T47916-", - "T47917-", - "G47918-", - "T47919-", - "T47920-", - "A47921-", - "T47922-", - "A47923-", - "G47924-", - "A47925-", - "A47926-", - "T47927-", - "G47928-", - "C47929-", - "A47930-", - "T47931-", - "C47932-", - "C47933-", - "A47934-", - "A47935-", - "C47936-", - "A47937-", - "T47938-", - "T47939-", - "G47940-", - "T47941-", - "T47942-", - "C47943-", - "A47944-", - "T47945-", - "G47946-", - "A47947-", - "T47948-", - "A47949-", - "T47950-", - "A47951-", - "G47952-", - "T47953-", - "T47954-", - "G47955-", - "A47956-", - "A47957-", - "T47958-", - "C47959-", - "A47960-", - "T47961-", - "G47962-", - "T47963-", - "A47964-", - "T47965-", - "G47966-", - "C47967-", - "C47968-", - "T47969-", - "G47970-", - "T47971-", - "T47972-", - "C47973-", - "G47974-", - "T47975-", - "A47976-", - "T47977-", - "G47978-", - "C47979-", - "C47980-", - "T47981-", - "G47982-", - "T47983-", - "G47984-", - "G47985-", - "C47986-", - "T47987-", - "A47988-", - "A47989-", - "G47990-", - "A47991-", - "T47992-", - "A47993-", - "C47994-", - "T47995-", - "G47996-", - "T47997-", - "G47998-", - "T47999-", - "A48000-", - "A48001-", - "A48002-", - "G48003-", - "A48004-", - "A48005-", - "A48006-", - "T48007-", - "G48008-", - "G48009-", - "T48010-", - "A48011-", - "A48012-", - "A48013-", - "T48014-", - "A48015-", - "A48016-", - "A48017-", - "T48018-", - "T48021-", - "T48022-", - "T48023-", - "G48024-", - "A48025-", - "G48026-", - "A48027-", - "A48028-", - "T48029-", - "C48030-", - "T48031-", - "T48032-", - "T48033-", - "A48034-", - "A48035-", - "G48036-", - "A48037-", - "G48038-", - "T48039-", - "G48040-", - "C48041-", - "A48042-", - "T48043-", - "T48044-", - "G48045-", - "A48046-", - "C48047-", - "T48048-", - "T48049-", - "T48050-", - "G48051-", - "T48052-", - "T48053-", - "A48054-", - "G48055-", - "T48056-", - "G48057-", - "A48058-", - "A48059-", - "T48060-", - "A48061-", - "G48062-", - "G48063-", - "C48064-", - "A48065-", - "T48066-", - "T48067-", - "C48068-", - "C48069-", - "A48070-", - "T48071-", - "C48072-", - "T48073-", - "T48074-", - "T48075-", - "C48076-", - "T48077-", - "C48078-", - "C48079-", - "A48080-", - "A48081-", - "T48082-", - "A48083-", - "C48084-", - "T48085-", - "A48086-", - "A48087-", - "T48088-", - "T48089-", - "C48090-", - "A48091-", - "A48092-", - "A48093-", - "T48094-", - "T48095-", - "G48096-", - "T48097-", - "T48098-", - "A48099-", - "A48100-", - "A48101-", - "T48102-", - "T48103-", - "A48104-", - "A48105-", - "T48106-", - "A48107-", - "A48108-", - "T48109-", - "G48110-", - "G48111-", - "A48112-", - "A48113-", - "T48114-", - "A48115-", - "G48116-", - "T48117-", - "A48118-", - "T48119-", - "A48120-", - "A48121-", - "A48122-", - "T48123-", - "A48124-", - "G48125-", - "T48126-", - "T48127-", - "A48128-", - "T48129-", - "T48130-", - "A48131-", - "G48132-", - "T48133-", - "G48134-", - "A48135-", - "T48136-", - "A48137-", - "G48138-", - "G48139-", - "A48140-", - "T48141-", - "A48142-", - "G48143-", - "T48144-", - "A48145-", - "A48146-", - "A48147-", - "C48148-", - "A48149-", - "T48150-", - "A48151-", - "A48152-", - "T48153-", - "T48154-", - "A48155-", - "T48156-", - "T48157-", - "A48158-", - "G48159-", - "A48160-", - "A48161-", - "T48162-", - "A48163-", - "G48164-", - "T48165-", - "A48166-", - "G48167-", - "T48168-", - "G48169-", - "T48170-", - "A48171-", - "G48172-", - "T48173-", - "A48174-", - "T48175-", - "C48176-", - "A48177-", - "T48178-", - "A48179-", - "G48180-", - "A48181-", - "T48182-", - "A48183-", - "A48184-", - "C48185-", - "T48186-", - "C48187-", - "T48188-", - "C48189-", - "T48190-", - "T48191-", - "C48192-", - "T48193-", - "A48194-", - "T48195-", - "A48196-", - "A48197-", - "A48198-", - "A48199-", - "A48200-", - "A48201-", - "T48202-", - "G48203-", - "G48204-", - "A48205-", - "T48206-", - "T48207-", - "T48208-", - "T48209-", - "A48210-", - "T48211-", - "T48212-", - "C48213-", - "G48214-", - "T48215-", - "A48216-", - "G48217-", - "A48218-", - "A48219-", - "A48220-", - "G48221-", - "T48222-", - "A48223-", - "T48224-", - "C48225-", - "T48226-", - "T48227-", - "A48228-", - "T48229-", - "A48230-", - "T48231-", - "A48232-", - "C48233-", - "A48234-", - "C48235-", - "A48236-", - "G48237-", - "T48238-", - "A48239-", - "G48240-", - "A48241-", - "A48242-", - "A48243-", - "A48244-", - "T48245-", - "A48246-", - "A48247-", - "T48248-", - "A48249-", - "T48250-", - "A48251-", - "G48252-", - "A48253-", - "T48254-", - "T48255-", - "T48256-", - "T48257-", - "T48258-", - "T48259-", - "A48260-", - "A48261-", - "A48262-", - "G48263-", - "G48264-", - "A48265-", - "T48266-", - "G48267-", - "A48268-", - "T48269-", - "A48270-", - "C48271-", - "A48272-", - "T48273-", - "T48274-", - "A48275-", - "A48276-", - "G48277-", - "T48278-", - "A48279-", - "A48280-", - "A48281-", - "G48282-", - "T48283-", - "A48284-", - "A48285-", - "A48286-", - "C48287-", - "A48288-", - "A48289-", - "T48290-", - "T48291-", - "T48292-", - "T48293-", - "A48294-", - "C48295-", - "C48296-", - "C48297-", - "T48298-", - "C48299-", - "A48300-", - "A48301-", - "T48302-", - "C48303-", - "A48304-", - "T48305-", - "G48306-", - "T48307-", - "A48308-", - "C48309-", - "T48310-", - "A48311-", - "G48312-", - "C48313-", - "T48314-", - "C48315-", - "T48316-", - "C48317-", - "A48318-", - "A48319-", - "G48320-", - "T48321-", - "A48322-", - "T48323-", - "C48324-", - "T48325-", - "A48326-", - "G48327-", - "T48328-", - "T48329-", - "A48330-", - "G48331-", - "C48332-", - "A48333-", - "A48334-", - "T48335-", - "T48336-", - "T48337-", - "T48338-", - "C48339-", - "C48340-", - "T48341-", - "C48342-", - "A48343-", - "A48344-", - "C48345-", - "A48346-", - "T48347-", - "G48348-", - "T48349-", - "T48350-", - "A48351-", - "T48352-", - "T48353-", - "A48354-", - "C48355-", - "T48356-", - "A48357-", - "A48358-", - "G48359-", - "G48360-", - "A48361-", - "T48362-", - "G48363-", - "T48364-", - "A48365-", - "T48366-", - "T48367-", - "A48368-", - "G48369-", - "C48370-", - "T48371-", - "A48372-", - "A48373-", - "T48374-", - "A48375-", - "C48376-", - "C48377-", - "A48378-", - "A48379-", - "T48380-", - "T48381-", - "T48382-", - "T48383-", - "T48384-", - "T48385-", - "T48386-", - "G48387-", - "T48388-", - "T48389-", - "T48390-", - "T48391-", - "C48392-", - "A48393-", - "T48394-", - "A48395-", - "C48396-", - "A48397-", - "T48398-", - "A48399-", - "T48400-", - "G48401-", - "G48402-", - "T48403-", - "A48404-", - "C48405-", - "G48406-", - "A48407-", - "T48408-", - "G48409-", - "C48410-", - "T48411-", - "G48412-", - "T48413-", - "A48414-", - "A48415-", - "A48416-", - "G48417-", - "T48418-", - "A48419-", - "T48420-", - "A48421-", - "C48422-", - "G48423-", - "A48424-", - "A48425-", - "G48426-", - "C48427-", - "G48428-", - "G48429-", - "T48430-", - "T48431-", - "T48432-", - "T48433-", - "A48434-", - "C48435-", - "G48436-", - "A48437-", - "C48438-", - "A48439-", - "C48440-", - "G48441-", - "C48442-", - "A48443-", - "T48444-", - "T48445-", - "T48446-", - "G48447-", - "A48448-", - "T48449-", - "G48450-", - "C48451-", - "A48452-", - "C48453-", - "C48454-", - "C48455-", - "A48456-", - "C48457-", - "G48458-", - "T48459-", - "T48460-", - "G48461-", - "T48462-", - "A48463-", - "C48464-", - "G48465-", - "T48466-", - "T48467-", - "A48468-", - "A48469-", - "A48470-", - "G48471-", - "C48472-", - "A48473-", - "T48474-", - "T48475-", - "G48476-", - "A48477-", - "C48478-", - "T48479-", - "A48480-", - "A48481-", - "G48482-", - "A48483-", - "A48484-", - "T48485-", - "T48486-", - "A48487-", - "T48488-", - "T48489-", - "T48490-", - "A48491-", - "T48492-", - "C48493-", - "G48494-", - "T48495-", - "T48496-", - "T48497-", - "A48498-", - "G48499-", - "T48500-", - "A48501-", - "A48502-", - "C48503-", - "A48504-", - "C48505-", - "A48506-", - "A48507-", - "T48508-", - "A48509-", - "C48510-", - "A48511-", - "G48512-", - "T48513-", - "C48514-", - "G48515-", - "T48516-", - "A48517-", - "C48518-", - "A48519-", - "A48520-", - "G48521-", - "G48522-", - "A48523-", - "A48524-", - "A48525-", - "C48526-", - "A48527-", - "G48528-", - "T48529-", - "G48530-", - "C48531-", - "A48532-", - "T48533-", - "A48534-", - "A48535-", - "A48536-", - "C48537-", - "T48538-", - "A48539-", - "A48540-", - "C48541-", - "A48542-", - "C48543-", - "A48544-", - "A48545-", - "G48546-", - "A48547-", - "T48548-", - "G48549-", - "A48550-", - "A48551-", - "A48552-", - "A48553-", - "A48554-", - "T48555-", - "T48556-", - "T48557-", - "T48558-", - "T48559-", - "A48560-", - "G48561-", - "A48562-", - "G48563-", - "G48564-", - "T48565-", - "T48566-", - "G48567-", - "C48568-", - "C48569-", - "G48570-", - "A48571-", - "A48572-", - "T48573-", - "A48574-", - "C48575-", - "A48576-", - "T48577-", - "G48578-", - "G48579-", - "A48580-", - "C48581-", - "G48582-", - "A48583-", - "A48584-", - "T48585-", - "T48586-", - "A48587-", - "G48588-", - "G48589-", - "A48590-", - "G48591-", - "A48592-", - "A48593-", - "C48594-", - "T48595-", - "T48596-", - "A48597-", - "T48598-", - "A48599-", - "G48600-", - "G48601-", - "C48602-", - "G48603-", - "T48604-", - "A48605-", - "A48606-", - "A48607-", - "T48608-", - "T48609-", - "A48610-", - "T48611-", - "G48612-", - "A48613-", - "C48614-", - "T48615-", - "T48616-", - "A48617-", - "G48618-", - "T48619-", - "T48620-", - "C48621-", - "T48622-", - "T48623-", - "A48624-", - "A48625-", - "T48626-", - "C48627-", - "C48628-", - "A48629-", - "T48630-", - "T48631-", - "A48632-", - "T48633-", - "T48634-", - "T48635-", - "C48636-", - "A48637-", - "C48638-", - "G48639-", - "G48640-", - "A48641-", - "G48642-", - "G48643-", - "G48644-", - "G48645-", - "A48646-", - "A48647-", - "C48648-", - "C48649-", - "C48650-", - "A48651-", - "T48652-", - "C48653-", - "A48654-", - "A48655-", - "A48656-", - "G48657-", - "A48658-", - "T48659-", - "A48660-", - "T48661-", - "G48662-", - "G48663-", - "A48664-", - "A48665-", - "A48666-", - "T48667-", - "C48668-", - "A48669-", - "T48670-", - "T48671-", - "T48672-", - "T48673-", - "T48674-", - "T48675-", - "T48676-", - "A48677-", - "A48678-", - "A48679-", - "A48680-", - "C48681-", - "T48682-", - "G48683-", - "T48684-", - "T48685-", - "T48686-", - "A48687-", - "A48688-", - "G48689-", - "A48690-", - "A48691-", - "A48692-", - "A48693-", - "C48694-", - "A48695-", - "G48696-", - "A48697-", - "C48698-", - "T48699-", - "T48700-", - "C48701-", - "A48702-", - "A48703-", - "A48704-", - "G48705-", - "T48706-", - "T48707-", - "G48708-", - "T48709-", - "T48710-", - "A48711-", - "A48712-", - "A48713-", - "A48714-", - "A48715-", - "A48716-", - "T48717-", - "T48718-", - "A48719-", - "A48720-", - "G48721-", - "T48722-", - "G48723-", - "T48724-", - "T48725-", - "A48726-", - "T48727-", - "A48728-", - "A48729-", - "G48730-", - "A48731-", - "T48732-", - "T48733-", - "A48734-", - "C48735-", - "T48736-", - "T48737-", - "A48738-", - "T48739-", - "T48740-", - "T48741-", - "G48742-", - "G48743-", - "G48744-", - "C48745-", - "A48746-", - "T48747-", - "A48748-", - "C48749-", - "C48750-", - "T48751-", - "A48752-", - "A48753-", - "G48754-", - "C48755-", - "A48756-", - "A48757-", - "G48758-", - "A48759-", - "A48760-", - "A48761-", - "G48762-", - "A48763-", - "T48764-", - "A48765-", - "C48766-", - "A48767-", - "G48768-", - "G48769-", - "C48770-", - "A48771-", - "T48772-", - "A48773-", - "G48774-", - "A48775-", - "G48776-", - "T48777-", - "T48778-", - "T48779-", - "G48780-", - "C48781-", - "G48782-", - "G48783-", - "A48784-", - "T48785-", - "A48786-", - "A48787-", - "T48788-", - "G48789-", - "A48790-", - "T48791-", - "A48792-", - "G48793-", - "A48794-", - "C48795-", - "A48796-", - "A48797-", - "G48798-", - "A48799-", - "T48800-", - "A48801-", - "T48802-", - "A48803-", - "T48804-", - "A48805-", - "T48806-", - "A48807-", - "C48808-", - "T48809-", - "C48810-", - "T48811-", - "A48812-", - "T48813-", - "T48814-", - "T48815-", - "C48816-", - "A48817-", - "A48818-", - "C48819-", - "A48820-", - "A48821-", - "A48822-", - "C48823-", - "T48824-", - "G48825-", - "G48826-", - "T48827-", - "A48828-", - "G48829-", - "A48830-", - "A48831-", - "T48832-", - "A48833-", - "G48834-", - "T48835-", - "C48836-", - "C48837-", - "A48838-", - "T48839-", - "A48840-", - "G48841-", - "C48842-", - "A48843-", - "A48844-", - "T48845-", - "C48846-", - "T48847-", - "A48848-", - "A48849-", - "C48850-", - "A48851-", - "G48852-", - "A48853-", - "A48854-", - "A48855-", - "C48856-", - "G48857-", - "T48858-", - "T48859-", - "T48860-", - "A48861-", - "G48862-", - "G48863-", - "G48864-", - "A48865-", - "T48866-", - "T48867-", - "A48868-", - "T48869-", - "A48870-", - "T48871-", - "C48872-", - "T48873-", - "T48874-", - "T48875-", - "C48876-", - "C48877-", - "C48878-", - "G48879-", - "G48880-", - "A48881-", - "G48882-", - "A48883-", - "T48884-", - "A48885-", - "A48886-", - "G48887-", - "A48888-", - "C48889-", - "T48890-", - "A48891-", - "G48892-", - "C48893-", - "T48894-", - "A48895-", - "T48896-", - "T48897-", - "G48898-", - "G48899-", - "G48900-", - "T48901-", - "G48902-", - "T48903-", - "G48904-", - "G48905-", - "T48906-", - "T48907-", - "A48908-", - "A48909-", - "A48910-", - "C48911-", - "G48912-", - "A48913-", - "A48914-", - "A48915-", - "G48916-", - "T48917-", - "A48918-", - "T48919-", - "A48920-", - "G48921-", - "C48922-", - "T48923-", - "A48924-", - "A48925-", - "T48926-", - "G48927-", - "A48928-", - "T48929-", - "G48930-", - "C48931-", - "G48932-", - "G48933-", - "A48934-", - "T48935-", - "A48936-", - "T48937-", - "C48938-", - "G48939-", - "T48940-", - "T48941-", - "A48942-", - "T48943-", - "T48944-", - "A48945-", - "A48946-", - "T48947-", - "A48948-", - "G48949-", - "A48950-", - "C48951-", - "C48952-", - "C48953-", - "G48954-", - "C48955-", - "C48956-", - "A48957-", - "T48958-", - "T48959-", - "A48960-", - "C48961-", - "C48962-", - "A48963-", - "T48964-", - "G48965-", - "T48966-", - "A48967-", - "T48968-", - "G48969-", - "A48970-", - "T48971-", - "A48972-", - "A48973-", - "A48974-", - "A48975-", - "T48976-", - "T48977-", - "C48978-", - "T48979-", - "T48980-", - "A48981-", - "G48982-", - "T48983-", - "T48984-", - "A48985-", - "T48986-", - "A48987-", - "T48988-", - "A48989-", - "T48990-", - "A48991-", - "C48992-", - "T48993-", - "C48994-", - "T48995-", - "G48996-", - "A48997-", - "G48998-", - "A48999-", - "T49000-", - "A49001-", - "A49002-", - "A49003-", - "A49004-", - "C49005-", - "A49006-", - "G49007-", - "G49008-", - "G49009-", - "A49010-", - "C49011-", - "G49012-", - "C49013-", - "G49014-", - "T49015-", - "T49016-", - "A49017-", - "A49018-", - "T49019-", - "A49020-", - "A49021-", - "A49022-", - "A49023-", - "A49024-", - "C49025-", - "A49026-", - "T49027-", - "G49028-", - "C49029-", - "T49030-", - "T49031-", - "A49032-", - "A49033-", - "G49034-", - "T49035-", - "T49036-", - "A49037-", - "G49038-", - "T49039-", - "T49040-", - "T49041-", - "A49042-", - "T49043-", - "A49044-", - "T49045-", - "C49046-", - "T49047-", - "T49048-", - "T49049-", - "G49050-", - "A49051-", - "G49052-", - "C49053-", - "C49054-", - "T49055-", - "G49056-", - "A49057-", - "A49058-", - "A49059-", - "A49060-", - "A49061-", - "G49062-", - "A49063-", - "T49064-", - "A49065-", - "T49066-", - "C49067-", - "A49068-", - "G49069-", - "A49070-", - "G49071-", - "A49072-", - "A49073-", - "C49074-", - "T49075-", - "T49076-", - "C49077-", - "T49078-", - "G49079-", - "C49080-", - "T49081-", - "A49082-", - "G49083-", - "A49084-", - "A49085-", - "A49086-", - "T49087-", - "C49088-", - "A49089-", - "T49090-", - "A49091-", - "T49092-", - "A49093-", - "T49094-", - "G49095-", - "A49096-", - "T49097-", - "A49098-", - "T49099-", - "T49100-", - "C49101-", - "C49102-", - "T49103-", - "G49104-", - "G49105-", - "A49106-", - "G49107-", - "A49108-", - "T49109-", - "A49110-", - "T49111-", - "C49112-", - "C49113-", - "T49114-", - "A49115-", - "T49116-", - "C49117-", - "T49118-", - "A49119-", - "T49120-", - "T49121-", - "A49122-", - "T49123-", - "T49124-", - "G49125-", - "A49126-", - "T49127-", - "G49128-", - "C49129-", - "A49130-", - "A49131-", - "A49132-", - "A49133-", - "A49134-", - "A49135-", - "C49136-", - "G49137-", - "A49138-", - "C49139-", - "G49140-", - "A49141-", - "T49142-", - "T49143-", - "G49144-", - "G49145-", - "A49146-", - "A49147-", - "A49148-", - "A49149-", - "A49150-", - "A49151-", - "T49152-", - "A49153-", - "T49154-", - "T49155-", - "T49156-", - "T49157-", - "A49158-", - "T49159-", - "T49160-", - "A49161-", - "G49162-", - "T49163-", - "T49164-", - "T49165-", - "T49166-", - "T49167-", - "A49168-", - "C49169-", - "A49170-", - "A49171-", - "A49172-", - "G49173-", - "C49174-", - "T49175-", - "A49176-", - "A49177-", - "T49178-", - "T49179-", - "T49180-", - "T49181-", - "A49182-", - "T49183-", - "T49184-", - "A49185-", - "A49186-", - "C49187-", - "G49188-", - "G49189-", - "T49190-", - "A49191-", - "A49192-", - "T49193-", - "A49194-", - "C49195-", - "A49196-", - "T49197-", - "T49198-", - "T49199-", - "A49200-", - "T49201-", - "T49202-", - "A49203-", - "G49204-", - "T49205-", - "G49206-", - "A49207-", - "T49208-", - "A49209-", - "G49210-", - "A49211-", - "A49212-", - "C49213-", - "G49214-", - "T49215-", - "T49216-", - "T49217-", - "A49218-", - "A49219-", - "C49220-", - "G49221-", - "A49222-", - "T49223-", - "G49224-", - "A49225-", - "C49226-", - "T49227-", - "T49228-", - "A49229-", - "T49230-", - "T49231-", - "C49232-", - "A49233-", - "G49234-", - "A49235-", - "G49236-", - "T49237-", - "T49238-", - "G49239-", - "T49240-", - "T49241-", - "G49242-", - "T49243-", - "T49244-", - "C49245-", - "A49246-", - "A49247-", - "A49248-", - "T49249-", - "A49250-", - "G49251-", - "A49252-", - "T49253-", - "C49254-", - "C49255-", - "C49256-", - "G49257-", - "A49258-", - "A49259-", - "T49260-", - "A49261-", - "T49262-", - "T49263-", - "T49264-", - "C49265-", - "G49266-", - "A49267-", - "T49268-", - "A49269-", - "A49270-", - "T49271-", - "G49272-", - "A49273-", - "A49274-", - "C49275-", - "G49276-", - "A49277-", - "A49278-", - "T49279-", - "T49280-", - "A49281-", - "T49282-", - "G49283-", - "T49284-", - "C49285-", - "T49286-", - "T49287-", - "T49288-", - "A49289-", - "T49290-", - "T49291-", - "C49292-", - "T49293-", - "A49294-", - "T49295-", - "A49296-", - "C49297-", - "G49298-", - "A49299-", - "G49300-", - "T49301-", - "G49302-", - "C49303-", - "T49304-", - "G49305-", - "C49306-", - "G49307-", - "G49308-", - "A49309-", - "C49310-", - "A49311-", - "T49312-", - "T49313-", - "A49314-", - "A49315-", - "A49316-", - "C49317-", - "G49318-", - "A49319-", - "T49320-", - "T49321-", - "T49322-", - "G49323-", - "A49324-", - "T49325-", - "G49326-", - "A49327-", - "G49328-", - "T49329-", - "T49330-", - "A49331-", - "G49332-", - "A49333-", - "T49334-", - "A49335-", - "T49336-", - "T49337-", - "A49338-", - "A49339-", - "T49340-", - "A49341-", - "A49342-", - "C49343-", - "A49344-", - "G49345-", - "T49346-", - "T49347-", - "A49348-", - "T49349-", - "A49350-", - "T49351-", - "A49352-", - "T49353-", - "C49354-", - "T49355-", - "A49356-", - "A49357-", - "T49358-", - "A49359-", - "T49360-", - "A49361-", - "A49362-", - "T49363-", - "T49364-", - "T49365-", - "A49366-", - "T49367-", - "G49368-", - "A49369-", - "G49370-", - "G49371-", - "T49372-", - "G49373-", - "A49374-", - "A49375-", - "C49376-", - "G49377-", - "A49378-", - "T49379-", - "A49380-", - "T49381-", - "C49382-", - "A49383-", - "C49384-", - "A49385-", - "T49386-", - "T49387-", - "A49388-", - "G49389-", - "A49390-", - "T49391-", - "A49392-", - "C49393-", - "A49394-", - "A49395-", - "T49396-", - "G49397-", - "G49398-", - "A49399-", - "T49400-", - "G49401-", - "A49402-", - "T49403-", - "A49404-", - "T49405-", - "G49406-", - "A49407-", - "A49408-", - "G49409-", - "A49410-", - "A49411-", - "G49412-", - "T49413-", - "G49414-", - "T49415-", - "C49416-", - "A49417-", - "A49418-", - "A49419-", - "T49420-", - "C49421-", - "T49422-", - "T49423-", - "T49424-", - "A49425-", - "A49426-", - "C49427-", - "G49428-", - "A49429-", - "G49430-", - "G49431-", - "A49432-", - "T49433-", - "A49434-", - "C49435-", - "G49436-", - "T49437-", - "T49438-", - "G49439-", - "T49440-", - "A49441-", - "T49442-", - "T49443-", - "A49444-", - "T49445-", - "G49446-", - "T49447-", - "T49448-", - "A49449-", - "A49450-", - "G49451-", - "G49452-", - "A49453-", - "A49454-", - "T49455-", - "A49456-", - "C49457-", - "A49458-", - "A49459-", - "T49460-", - "A49461-", - "C49462-", - "A49463-", - "T49464-", - "A49465-", - "C49466-", - "C49467-", - "T49468-", - "G49469-", - "T49470-", - "T49471-", - "T49472-", - "T49473-", - "T49474-", - "G49475-", - "C49476-", - "A49477-", - "C49478-", - "G49479-", - "A49480-", - "G49481-", - "T49482-", - "C49483-", - "G49484-", - "G49485-", - "A49486-", - "T49487-", - "C49488-", - "C49489-", - "C49490-", - "A49491-", - "T49492-", - "G49493-", - "G49494-", - "T49495-", - "C49496-", - "A49497-", - "T49498-", - "A49499-", - "G49500-", - "A49501-", - "G49502-", - "A49503-", - "A49504-", - "C49505-", - "G49506-", - "G49507-", - "A49508-", - "A49509-", - "T49510-", - "A49511-", - "C49512-", - "T49513-", - "A49514-", - "A49515-", - "A49516-", - "G49517-", - "A49518-", - "A49519-", - "A49520-", - "C49521-", - "T49522-", - "G49523-", - "T49524-", - "C49525-", - "A49526-", - "T49527-", - "C49528-", - "T49529-", - "A49530-", - "T49531-", - "A49532-", - "A49533-", - "A49534-", - "A49535-", - "T49536-", - "C49537-", - "C49538-", - "A49539-", - "A49540-", - "G49541-", - "A49542-", - "G49543-", - "T49544-", - "A49545-", - "G49546-", - "A49547-", - "C49548-", - "G49549-", - "G49550-", - "C49551-", - "T49552-", - "G49553-", - "A49554-", - "A49555-", - "C49556-", - "T49557-", - "T49558-", - "G49559-", - "T49560-", - "T49561-", - "T49562-", - "A49563-", - "G49564-", - "C49565-", - "A49566-", - "A49567-", - "A49568-", - "A49569-", - "A49570-", - "C49571-", - "A49572-", - "T49573-", - "T49574-", - "T49575-", - "T49576-", - "A49577-", - "A49578-", - "A49579-", - "A49580-", - "T49581-", - "A49582-", - "T49583-", - "T49584-", - "A49585-", - "T49586-", - "T49587-", - "T49588-", - "A49589-", - "G49590-", - "A49591-", - "C49592-", - "G49593-", - "G49594-", - "A49595-", - "C49596-", - "A49597-", - "A49598-", - "T49599-", - "T49600-", - "G49601-", - "G49602-", - "C49603-", - "T49604-", - "C49605-", - "G49606-", - "T49607-", - "C49608-", - "T49609-", - "A49610-", - "G49611-", - "G49612-", - "T49613-", - "C49614-", - "T49615-", - "T49616-", - "G49617-", - "T49618-", - "G49619-", - "T49620-", - "T49621-", - "A49622-", - "G49623-", - "A49624-", - "T49625-", - "G49626-", - "A49627-", - "T49628-", - "T49629-", - "A49630-", - "T49631-", - "A49632-", - "A49633-", - "A49634-", - "G49635-", - "G49636-", - "A49637-", - "G49638-", - "A49639-", - "C49640-", - "T49641-", - "T49642-", - "A49643-", - "T49644-", - "T49645-", - "A49646-", - "G49647-", - "T49648-", - "T49649-", - "A49650-", - "A49651-", - "A49652-", - "A49653-", - "T49654-", - "G49655-", - "A49656-", - "T49657-", - "A49658-", - "A49659-", - "A49660-", - "C49661-", - "C49662-", - "A49663-", - "T49664-", - "C49665-", - "T49666-", - "C49667-", - "A49668-", - "A49669-", - "A49670-", - "T49671-", - "C49672-", - "T49673-", - "G49674-", - "T49675-", - "G49676-", - "G49677-", - "A49678-", - "G49680-", - "A49681-", - "T49682-", - "G49683-", - "T49684-", - "A49685-", - "T49686-", - "C49687-", - "C49688-", - "G49689-", - "C49690-", - "A49691-", - "T49692-", - "T49693-", - "C49694-", - "G49695-", - "T49696-", - "T49697-", - "A49698-", - "G49699-", - "A49700-", - "T49701-", - "T49702-", - "T49703-", - "T49704-", - "C49705-", - "T49706-", - "C49708-", - "A49709-", - "G49710-", - "G61679-", - "G61786-", - "C61787-", - "T61788-", - "A61789-", - "A61791-", - "A61792-", - "T61793-", - "G61794-", - "C61796-", - "A61815-", - "G61816-", - "T61817-", - "A61818-", - "C61819-", - "A61820-", - "A61821-", - "G61822-", - "T61823-", - "G61824-", - "G61825-", - "C61826-", - "T61827-", - "G61828-", - "C61829-", - "T61830-", - "A61831-", - "T61832-", - "T61833-", - "T61834-", - "C61835-", - "G61836-", - "G61837-", - "C61838-", - "T61839-", - "G61840-", - "C61841-", - "C61842-", - "A61843-", - "G61844-", - "A61845-", - "G61846-", - "T61847-", - "G61848-", - "T61849-", - "C61850-", - "C61851-", - "A61852-", - "A61853-", - "T61854-", - "T61855-", - "C61856-", - "T61857-", - "A61858-", - "C61859-", - "C61860-", - "G61861-", - "T61862-", - "T61863-", - "G61864-", - "T61865-", - "T61866-", - "A61867-", - "C61868-", - "T61869-", - "C61870-", - "C61871-", - "A61872-", - "T61873-", - "T61874-", - "A61875-", - "T61876-", - "A61877-", - "T61878-", - "A61879-", - "T61880-", - "T61881-", - "C61882-", - "C61883-", - "T61884-", - "T61885-", - "G61886-", - "A61887-", - "A61888-", - "T61889-", - "A61890-", - "A61891-", - "C61892-", - "C61893-", - "T61894-", - "T61895-", - "C61896-", - "A61897-", - "T61898-", - "A61899-", - "G61900-", - "C61901-", - "T61902-", - "A61903-", - "T61904-", - "T61905-", - "T61906-", - "T61907-", - "A61908-", - "A61909-", - "T61910-", - "A61911-", - "G61912-", - "G61913-", - "A61914-", - "T61915-", - "C61916-", - "T61917-", - "A61918-", - "T61919-", - "A61920-", - "T61921-", - "G61922-", - "A61923-", - "T61924-", - "C61925-", - "A61926-", - "G61927-", - "T61928-", - "G61929-", - "T61930-", - "T61931-", - "T61932-", - "A61933-", - "A61934-", - "G61935-", - "C61936-", - "C61937-", - "A61938-", - "T61939-", - "A61940-", - "G61941-", - "C61942-", - "A61943-", - "C61944-", - "A61945-", - "A61946-", - "T61947-", - "T61948-", - "T61949-", - "T61950-", - "C61951-", - "T61952-", - "A61953-", - "A61954-", - "T61955-", - "A61956-", - "C61957-", - "G61958-", - "A61959-", - "G61960-", - "A61961-", - "C61962-", - "G61963-", - "T61964-", - "G61965-", - "A61966-", - "T61967-", - "T61968-", - "T61969-", - "T61970-", - "A61971-", - "T61972-", - "C61973-", - "A61974-", - "A61975-", - "A61976-", - "C61977-", - "A61978-", - "T61979-", - "G61980-", - "A61981-", - "C61982-", - "A61983-", - "T61984-", - "T61985-", - "T61986-", - "T61987-", - "C61988-", - "C61989-", - "T61990-", - "T61991-", - "G61992-", - "T61993-", - "A61994-", - "T61995-", - "C61996-", - "C61997-", - "A61998-", - "T61999-", - "T62000-", - "T62001-", - "C62002-", - "G62003-", - "T62004-", - "T62005-", - "T62006-", - "A62007-", - "A62008-", - "T62009-", - "G62010-", - "A62011-", - "C62012-", - "A62013-", - "A62014-", - "A62015-", - "C62016-", - "A62017-", - "T62018-", - "T62019-", - "T62020-", - "T62021-", - "T62022-", - "G62023-", - "T62024-", - "T62025-", - "G62026-", - "G62027-", - "T62028-", - "G62029-", - "T62030-", - "A62031-", - "A62032-", - "T62033-", - "A62034-", - "A62035-", - "A62037-", - "A62041-", - "T62043-", - "A62044-", - "T62045-", - "T62046-", - "T62047-", - "A62048-", - "A62049-", - "T62050-", - "T62051-", - "T62052-", - "T62053-", - "T62054-", - "C62055-", - "A62056-", - "T62057-", - "T62058-", - "A62059-", - "A62060-", - "T62061-", - "A62062-", - "G62063-", - "G62064-", - "G62065-", - "A62066-", - "T62067-", - "T62068-", - "T62069-", - "G62070-", - "A62071-", - "C62072-", - "G62073-", - "T62074-", - "A62075-", - "T62076-", - "G62077-", - "T62078-", - "A62079-", - "G62080-", - "C62081-", - "G62082-", - "T62083-", - "A62084-", - "C62085-", - "A62086-", - "A62087-", - "A62088-", - "A62089-", - "T62090-", - "T62091-", - "A62092-", - "T62093-", - "C62094-", - "G62095-", - "T62096-", - "T62097-", - "C62098-", - "C62099-", - "T62100-", - "G62101-", - "G62102-", - "T62103-", - "A62104-", - "T62105-", - "T62149-", - "T62150-", - "A62151-", - "A62152-", - "A62153-", - "C62154-", - "T62155-", - "T62156-", - "T62157-", - "A62158-", - "A62159-", - "T62160-", - "G62161-", - "A62162-", - "T62163-", - "T62629-", - "T62630-", - "T62631-", - "T62632-", - "T62633-", - "A62634-", - "G62635-", - "G62636-", - "A62637-", - "A62638-", - "T62639-", - "G62640-", - "T62641-", - "A62642-", - "T62643-", - "G62644-", - "G62645-", - "A62646-", - "C62647-", - "T62648-", - "C62649-", - "G62650-", - "C62651-", - "G62652-", - "T62653-", - "T62654-", - "T62655-", - "A62656-", - "G62657-", - "A62658-", - "G62659-", - "G62660-", - "A62661-", - "G62662-", - "T62663-", - "G62664-", - "A62665-", - "A62666-", - "C62667-", - "G62668-", - "T62669-", - "C62670-", - "T62671-", - "T62672-", - "C62673-", - "G62674-", - "G62675-", - "A62676-", - "G62677-", - "T62678-", - "A62679-", - "G62680-", - "T62681-", - "A62682-", - "A62683-", - "A62684-", - "G62685-", - "G62686-", - "A62687-", - "T62688-", - "G62689-", - "A62690-", - "A63493-", - "C63494-", - "A63495-", - "T63496-", - "A63497-", - "T63498-", - "C63499-", - "A63500-", - "C63501-", - "A63502-", - "T63503-", - "T63504-", - "A63505-", - "A89100-", - "A89101-", - "A89102-", - "C89145-", - "T89146-", - "T89147-", - "G89148-", - "T89149-", - "C89150-", - "A89151-", - "T89153-", - "G89154-", - "A89155-", - "T89166-", - "G89167-", - "C89170-", - "C89180-", - "T89181-", - "T89182-", - "T89183-", - "A89184-", - "A89185-", - "A89216-", - "A89219-", - "A89220-", - "A89221-", - "T89222-", - "A89223-", - "G89224-", - "C89225-", - "C89228-", - "C89229-", - "G89231-", - "T89232-", - "G89233-", - "T89234-", - "T89235-", - "G89237-", - "C89288-", - "C89291-", - "C89327-", - "G89328-", - "A89329-", - "A89330-", - "A89373-", - "C89374-", - "T89375-", - "T89376-", - "A89377-", - "T89378-", - "A89379-", - "T89380-", - "T89381-", - "C89382-", - "G89383-", - "T89384-", - "G89385-", - "T89386-", - "C89387-", - "T89388-", - "A89389-", - "G89390-", - "T89391-", - "A89392-", - "G89393-", - "A89394-", - "T89397-", - "G89398-", - "A89399-", - "T89401-", - "T89402-", - "T89403-", - "T89409-", - "G89410-", - "G89411-", - "A89412-", - "A89413-", - "T89414-", - "T89419-", - "T89429-", - "G89431-", - "T89465-", - "T89501-", - "T89502-", - "G89555-", - "A89618-", - "T89625-", - "A89660-", - "T89661-", - "C89663-", - "T89664-", - "T89671-", - "A89674-", - "C89675-", - "A89676-", - "G89679-", - "G89683-", - "C89684-", - "T89700-", - "A89703-", - "A89704-", - "G89705-", - "A89706-", - "A89731-", - "C89801-", - "T89802-", - "A89874-", - "G89875-", - "A89966-", - "G89967-", - "C89968-", - "A90039-", - "A90040-", - "G90041-", - "C90046-", - "T90051-", - "T90102-", - "A90103-", - "C90104-", - "T90153-", - "A90160-", - "G90161-", - "C90163-", - "C90173-", - "G90177-", - "A90178-", - "C90179-", - "A90183-", - "T90186-", - "A90187-", - "T90204-", - "C90213-", - "G90214-", - "G90232-", - "T90233-", - "G90331-", - "C90333-", - "C151552T", - "C167451T", - "-178815A", - "-178817A", - "-178819A", - "-178820A", - "-178821A", - "A178832-", - "G178833-", - "C178834-", - "T178835-", - "C178836-", - "T178837-", - "G178838-", - "C178839-", - "A178840-", - "T178841-", - "G194586-", - "T194587-", - "T194588-", - "G194589-", - "T194590-", - "C194591-", - "T194592-", - "A194593-", - "T194594-", - "C194595-", - "G194596-", - "T194597-", - "G194598-", - "T194599-" - ], - "OPG002": [ - "X43-", - "C44-", - "L45-", - "S46-", - "C47-", - "X350*" - ], - "OPG057": [ - "N267D" - ], - "OPG068": [ - "M1-", - "D2-", - "F3-", - "I4-", - "R5-", - "R6-", - "K7-", - "Y8-", - "L9-", - "I10-", - "Y11-", - "T12-", - "V13-", - "E14-", - "N15-", - "N16-", - "I17-", - "D18-", - "F19-", - "L20-", - "K21-", - "D22-", - "D23-", - "T24-", - "L25-", - "S26-", - "K27-", - "V28-", - "N29-", - "N30-", - "F31-", - "T32-", - "L33-", - "N34-", - "H35-", - "V36-", - "L37-", - "A38-", - "L39-", - "K40-", - "Y41-", - "L42-", - "V43-", - "S44-", - "N45-", - "F46-", - "P47-", - "Q48-", - "H49-", - "V50-", - "I51-", - "T52-", - "K53-", - "D54-", - "V55-", - "L56-", - "A57-", - "N58-", - "T59-", - "N60-", - "F61-", - "F62-", - "V63-", - "F64-", - "I65-", - "H66-", - "M67-", - "V68-", - "R69-", - "C70-", - "C71-", - "K72-", - "V73-", - "Y74-", - "E75-", - "A76-", - "V77-", - "L78-", - "R79-", - "H80-", - "A81-", - "F82-", - "D83-", - "A84-", - "P85-", - "T86-", - "L87-", - "Y88-", - "V89-", - "K90-", - "A91-", - "L92-", - "T93-", - "K94-", - "N95-", - "Y96-", - "L97-", - "S98-", - "F99-", - "S100-", - "N101-", - "T102-", - "I103-", - "Q104-", - "S105-", - "Y106-", - "K107-", - "E108-", - "T109-", - "V110-", - "H111-", - "K112-", - "L113-", - "T114-", - "Q115-", - "D116-", - "E117-", - "K118-", - "F119-", - "L120-", - "E121-", - "V122-", - "A123-", - "E124-", - "Y125-", - "M126-", - "D127-", - "E128-", - "L129-", - "G130-", - "E131-", - "L132-", - "I133-", - "G134-", - "V135-", - "N136-", - "Y137-", - "D138-", - "L139-", - "V140-", - "L141-", - "N142-", - "P143-", - "L144-", - "F145-", - "H146-", - "G147-", - "G148-", - "E149-", - "P150-", - "I151-", - "K152-", - "D153-", - "M154-", - "E155-", - "I156-", - "I157-", - "F158-", - "L159-", - "K160-", - "L161-", - "F162-", - "K163-", - "K164-", - "T165-", - "D166-", - "F167-", - "K168-", - "V169-", - "V170-", - "K171-", - "K172-", - "L173-", - "S174-", - "V175-", - "I176-", - "R177-", - "L178-", - "L179-", - "I180-", - "W181-", - "A182-", - "Y183-", - "L184-", - "S185-", - "K186-", - "K187-", - "D188-", - "T189-", - "G190-", - "I191-", - "E192-", - "F193-", - "A194-", - "D195-", - "N196-", - "D197-", - "R198-", - "Q199-", - "D200-", - "I201-", - "Y202-", - "T203-", - "L204-", - "F205-", - "Q206-", - "Q207-", - "T208-", - "G209-", - "R210-", - "I211-", - "V212-", - "H213-", - "S214-", - "N215-", - "L216-", - "T217-", - "E218-", - "T219-", - "F220-", - "R221-", - "D222-", - "Y223-", - "I224-", - "F225-", - "P226-", - "G227-", - "D228-", - "K229-", - "T230-", - "S231-", - "Y232-", - "W233-", - "V234-", - "W235-", - "L236-", - "N237-", - "E238-", - "S239-", - "I240-", - "A241-", - "N242-", - "D243-", - "A244-", - "D245-", - "I246-", - "V247-", - "I248-", - "N249-", - "R250-", - "P251-", - "A252-", - "I253-", - "T254-", - "M255-", - "Y256-", - "D257-", - "K258-", - "I259-", - "L260-", - "S261-", - "Y262-", - "I263-", - "Y264-", - "S265-", - "E266-", - "I267-", - "K268-", - "Q269-", - "G270-", - "R271-", - "V272-", - "N273-", - "K274-", - "N275-", - "M276-", - "L277-", - "K278-", - "L279-", - "V280-", - "Y281-", - "I282-", - "F283-", - "E284-", - "P285-", - "E286-", - "K287-", - "D288-", - "I289-", - "R290-", - "E291-", - "L292-", - "L293-", - "L294-", - "E295-", - "I296-", - "I297-", - "Y298-", - "D299-", - "I300-", - "P301-", - "G302-", - "D303-", - "I304-", - "L305-", - "S306-", - "I307-", - "I308-", - "D309-", - "A310-", - "K311-", - "N312-", - "D313-", - "D314-", - "W315-", - "K316-", - "K317-", - "Y318-", - "F319-", - "I320-", - "S321-", - "F322-", - "Y323-", - "K324-", - "A325-", - "N326-", - "F327-", - "I328-", - "N329-", - "G330-", - "N331-", - "T332-", - "F333-", - "I334-", - "S335-", - "D336-", - "R337-", - "T338-", - "F339-", - "N340-", - "D341-", - "D342-", - "L343-", - "F344-", - "R345-", - "V346-", - "V347-", - "V348-", - "Q349-", - "I350-", - "D351-", - "P352-", - "E353-", - "Y354-", - "F355-", - "D356-", - "N357-", - "E358-", - "R359-", - "I360-", - "M361-", - "S362-", - "L363-", - "F364-", - "Y365-", - "T366-", - "S367-", - "A368-", - "A369-", - "D370-", - "I371-", - "K372-", - "R373-", - "F374-", - "D375-", - "E376-", - "L377-", - "D378-", - "I379-", - "N380-", - "N381-", - "S382-", - "Y383-", - "I384-", - "S385-", - "N386-", - "I387-", - "I388-", - "Y389-", - "E390-", - "V391-", - "N392-", - "D393-", - "I394-", - "T395-", - "L396-", - "D397-", - "T398-", - "M399-", - "D400-", - "D401-", - "M402-", - "K403-", - "K404-", - "C405-", - "Q406-", - "I407-", - "F408-", - "N409-", - "E410-", - "D411-", - "T412-", - "L413-", - "Y414-", - "Y415-", - "V416-", - "K417-", - "E418-", - "Y419-", - "N420-", - "T421-", - "Y422-", - "L423-", - "F424-", - "L425-", - "H426-", - "E427-", - "S428-", - "D429-", - "P430-", - "M431-", - "V432-", - "I433-", - "E434-", - "N435-", - "G436-", - "I437-", - "L438-", - "K439-", - "K440-", - "L441-", - "S442-", - "S443-", - "I444-", - "K445-", - "S446-", - "K447-", - "S448-", - "R449-", - "R450-", - "L451-", - "N452-", - "L453-", - "F454-", - "S455-", - "K456-", - "N457-", - "I458-", - "L459-", - "K460-", - "Y461-", - "Y462-", - "L463-", - "D464-", - "G465-", - "Q466-", - "L467-", - "A468-", - "R469-", - "L470-", - "G471-", - "L472-", - "V473-", - "L474-", - "D475-", - "D476-", - "Y477-", - "K478-", - "G479-", - "D480-", - "L481-", - "L482-", - "V483-", - "K484-", - "M485-", - "I486-", - "N487-", - "H488-", - "L489-", - "K490-", - "S491-", - "V492-", - "X493-", - "D494-", - "V495-", - "S496-", - "A497-", - "F498-", - "V499-", - "R500-", - "F501-", - "S502-", - "X503-", - "D504X" - ], - "OPG080": [ - "M1-", - "F2-", - "V3-", - "I4-", - "K5-", - "R6-", - "N7-", - "G8-", - "Y9-", - "K10-", - "E11-", - "N12-", - "V13-", - "M14-", - "F15-", - "D16-", - "K17-", - "I18-", - "T19-", - "S20-", - "R21-", - "I22-", - "R23-", - "K24-", - "L25-", - "C26-", - "Y27-", - "G28-", - "L29-", - "N30-", - "T31-", - "D32-", - "H33-", - "I34-", - "D35-", - "P36-", - "I37-", - "K38-", - "I39-", - "A40-", - "M41-", - "K42-", - "V43-", - "I44-", - "Q45-", - "G46-", - "I47-", - "Y48-", - "N49-", - "G50-", - "V51-", - "T52-", - "T53-", - "V54-", - "E55-", - "L56-", - "D57-", - "T58-", - "L59-", - "A60-", - "A61-", - "E62-", - "I63-", - "A64-", - "A65-", - "T66-", - "C67-", - "T68-", - "A75X", - "I76-", - "L77X", - "A78X", - "P114X", - "*772X" - ], - "OPG081": [ - "X41-", - "S42-", - "L43-", - "K44-", - "F45-", - "X46-", - "I61-", - "P62-", - "G63-", - "T64-", - "I65-", - "I66-", - "L67-", - "Y68-", - "A69-", - "T70-", - "Y71-", - "V72-", - "K73-", - "S74-", - "L75-", - "L76-", - "M77-", - "K78-", - "N79-", - "X80-" - ], - "OPG082": [ - "S255-", - "S256-", - "F257-", - "T258-", - "T259-", - "P260-", - "K261-", - "T262-", - "F263-", - "T264-", - "P265-", - "L266-", - "N267-", - "A268-", - "S269-", - "P270-", - "Y271-", - "I272-", - "P273-", - "K274-", - "X275-" - ], - "OPG083": [ - "I404X", - "N405-", - "V406-", - "I407-", - "C408-" - ], - "OPG109": [ - "T6X", - "I7X", - "E10X", - "I12-", - "P13-", - "I15X", - "K16X", - "S17-", - "Y18X", - "L19-", - "L20-", - "D21-", - "T22-", - "N23-", - "I24-", - "S25-", - "F40-", - "V41X", - "E53X", - "D54X", - "Q71X", - "T72-", - "L73X", - "V74X", - "A75-", - "I76-", - "F77X", - "S78X", - "V88X", - "K89-", - "E90X", - "S93X", - "T94X", - "F98X", - "N99X", - "D100-", - "K101-", - "F116-", - "*796X" - ], - "OPG110": [ - "D10X", - "T11X", - "F14X", - "T15-", - "K16X", - "A18X", - "H23X", - "L24X", - "R25-", - "N34X", - "P57X", - "I81X", - "E82X", - "E112X", - "L113X", - "R136X", - "S137X", - "L139X", - "S140X", - "I157X", - "T158X", - "G174X", - "R177X", - "Q178X", - "S181X", - "M182X", - "T183X", - "K184X", - "A185X", - "I186X", - "D191X", - "T194X", - "E195X", - "V201X", - "*211X" - ], - "OPG111": [ - "D23X", - "*315X" - ], - "OPG178": [ - "S15F" - ] - }, - "labels": { - "aa": "OPG002: X43-, C44-, L45-, S46-, C47-, X350*; OPG057: N267D; OPG068: M1-, D2-, F3-, I4-, R5-, R6-, K7-, Y8-, L9-, I10-, Y11-, T12-, V13-, E14-, N15-, N16-, I17-, D18-, F19-, L20-, K21-, D22-, D23-, T24-, L25-, S26-, K27-, V28-, N29-, N30-, F31-, T32-, L33-, N34-, H35-, V36-, L37-, A38-, L39-, K40-, Y41-, L42-, V43-, S44-, N45-, F46-, P47-, Q48-, H49-, V50-, I51-, T52-, K53-, D54-, V55-, L56-, A57-, N58-, T59-, N60-, F61-, F62-, V63-, F64-, I65-, H66-, M67-, V68-, R69-, C70-, C71-, K72-, V73-, Y74-, E75-, A76-, V77-, L78-, R79-, H80-, A81-, F82-, D83-, A84-, P85-, T86-, L87-, Y88-, V89-, K90-, A91-, L92-, T93-, K94-, N95-, Y96-, L97-, S98-, F99-, S100-, N101-, T102-, I103-, Q104-, S105-, Y106-, K107-, E108-, T109-, V110-, H111-, K112-, L113-, T114-, Q115-, D116-, E117-, K118-, F119-, L120-, E121-, V122-, A123-, E124-, Y125-, M126-, D127-, E128-, L129-, G130-, E131-, L132-, I133-, G134-, V135-, N136-, Y137-, D138-, L139-, V140-, L141-, N142-, P143-, L144-, F145-, H146-, G147-, G148-, E149-, P150-, I151-, K152-, D153-, M154-, E155-, I156-, I157-, F158-, L159-, K160-, L161-, F162-, K163-, K164-, T165-, D166-, F167-, K168-, V169-, V170-, K171-, K172-, L173-, S174-, V175-, I176-, R177-, L178-, L179-, I180-, W181-, A182-, Y183-, L184-, S185-, K186-, K187-, D188-, T189-, G190-, I191-, E192-, F193-, A194-, D195-, N196-, D197-, R198-, Q199-, D200-, I201-, Y202-, T203-, L204-, F205-, Q206-, Q207-, T208-, G209-, R210-, I211-, V212-, H213-, S214-, N215-, L216-, T217-, E218-, T219-, F220-, R221-, D222-, Y223-, I224-, F225-, P226-, G227-, D228-, K229-, T230-, S231-, Y232-, W233-, V234-, W235-, L236-, N237-, E238-, S239-, I240-, A241-, N242-, D243-, A244-, D245-, I246-, V247-, I248-, N249-, R250-, P251-, A252-, I253-, T254-, M255-, Y256-, D257-, K258-, I259-, L260-, S261-, Y262-, I263-, Y264-, S265-, E266-, I267-, K268-, Q269-, G270-, R271-, V272-, N273-, K274-, N275-, M276-, L277-, K278-, L279-, V280-, Y281-, I282-, F283-, E284-, P285-, E286-, K287-, D288-, I289-, R290-, E291-, L292-, L293-, L294-, E295-, I296-, I297-, Y298-, D299-, I300-, P301-, G302-, D303-, I304-, L305-, S306-, I307-, I308-, D309-, A310-, K311-, N312-, D313-, D314-, W315-, K316-, K317-, Y318-, F319-, I320-, S321-, F322-, Y323-, K324-, A325-, N326-, F327-, I328-, N329-, G330-, N331-, T332-, F333-, I334-, S335-, D336-, R337-, T338-, F339-, N340-, D341-, D342-, L343-, F344-, R345-, V346-, V347-, V348-, Q349-, I350-, D351-, P352-, E353-, Y354-, F355-, D356-, N357-, E358-, R359-, I360-, M361-, S362-, L363-, F364-, Y365-, T366-, S367-, A368-, A369-, D370-, I371-, K372-, R373-, F374-, D375-, E376-, L377-, D378-, I379-, N380-, N381-, S382-, Y383-, I384-, S385-, N386-, I387-, I388-, Y389-, E390-, V391-, N392-, D393-, I394-, T395-, L396-, D397-, T398-, M399-, D400-, D401-, M402-, K403-, K404-, C405-, Q406-, I407-, F408-, N409-, E410-, D411-, T412-, L413-, Y414-, Y415-, V416-, K417-, E418-, Y419-, N420-, T421-, Y422-, L423-, F424-, L425-, H426-, E427-, S428-, D429-, P430-, M431-, V432-, I433-, E434-, N435-, G436-, I437-, L438-, K439-, K440-, L441-, S442-, S443-, I444-, K445-, S446-, K447-, S448-, R449-, R450-, L451-, N452-, L453-, F454-, S455-, K456-, N457-, I458-, L459-, K460-, Y461-, Y462-, L463-, D464-, G465-, Q466-, L467-, A468-, R469-, L470-, G471-, L472-, V473-, L474-, D475-, D476-, Y477-, K478-, G479-, D480-, L481-, L482-, V483-, K484-, M485-, I486-, N487-, H488-, L489-, K490-, S491-, V492-, X493-, D494-, V495-, S496-, A497-, F498-, V499-, R500-, F501-, S502-, X503-, D504X; OPG080: M1-, F2-, V3-, I4-, K5-, R6-, N7-, G8-, Y9-, K10-, E11-, N12-, V13-, M14-, F15-, D16-, K17-, I18-, T19-, S20-, R21-, I22-, R23-, K24-, L25-, C26-, Y27-, G28-, L29-, N30-, T31-, D32-, H33-, I34-, D35-, P36-, I37-, K38-, I39-, A40-, M41-, K42-, V43-, I44-, Q45-, G46-, I47-, Y48-, N49-, G50-, V51-, T52-, T53-, V54-, E55-, L56-, D57-, T58-, L59-, A60-, A61-, E62-, I63-, A64-, A65-, T66-, C67-, T68-, A75X, I76-, L77X, A78X, P114X, *772X; OPG081: X41-, S42-, L43-, K44-, F45-, X46-, I61-, P62-, G63-, T64-, I65-, I66-, L67-, Y68-, A69-, T70-, Y71-, V72-, K73-, S74-, L75-, L76-, M77-, K78-, N79-, X80-; OPG082: S255-, S256-, F257-, T258-, T259-, P260-, K261-, T262-, F263-, T264-, P265-, L266-, N267-, A268-, S269-, P270-, Y271-, I272-, P273-, K274-, X275-; OPG083: I404X, N405-, V406-, I407-, C408-; OPG109: T6X, I7X, E10X, I12-, P13-, I15X, K16X, S17-, Y18X, L19-, L20-, D21-, T22-, N23-, I24-, S25-, F40-, V41X, E53X, D54X, Q71X, T72-, L73X, V74X, A75-, I76-, F77X, S78X, V88X, K89-, E90X, S93X, T94X, F98X, N99X, D100-, K101-, F116-, *796X; OPG110: D10X, T11X, F14X, T15-, K16X, A18X, H23X, L24X, R25-, N34X, P57X, I81X, E82X, E112X, L113X, R136X, S137X, L139X, S140X, I157X, T158X, G174X, R177X, Q178X, S181X, M182X, T183X, K184X, A185X, I186X, D191X, T194X, E195X, V201X, *211X; OPG111: D23X, *315X; OPG178: S15F" - } - }, - "children": [ - { - "name": "28022023_anal", - "node_attrs": { - "div": 7, - "author": { - "author": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K.", - "value": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K." - }, - "strain_original": { - "value": "28022023_anal" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ672579" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-02-28" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G61785-", - "C70785-", - "G70786-", - "T70787-", - "A70788-", - "T70789-", - "A70790-", - "T70827-", - "C70828-", - "A70869-", - "T70870-", - "T70871-", - "T70872-", - "A70873-", - "G70874-", - "A70875-", - "G70876-", - "A70877-", - "G70878-", - "C70879-", - "G70880-", - "T70881-", - "G70882-", - "C70883-", - "C70884-", - "G70907-", - "C70908-", - "A70909-", - "T70910-", - "T70911-", - "A70912-", - "G70913-", - "A70914-", - "A70915-", - "C70916-", - "C70917-", - "A70918-", - "C70919-", - "G70920-", - "T70921-", - "C70938-", - "A70939-", - "G70940-", - "A70962-", - "T70969-", - "T70970-", - "T70971-", - "C70972-", - "G70973-", - "A70974-", - "A70975-", - "A70976-", - "A70977-", - "T70978-", - "A70979-", - "C70980-", - "T70981-", - "A70982-", - "A70983-", - "A70984-", - "T70985-", - "C70986-", - "T71023-", - "G71024-", - "G71025-", - "A71026-", - "T71027-", - "A71028-", - "T71029-", - "T71030-", - "C71031-", - "T71032-", - "A71033-", - "A71034-", - "C71035-", - "G71036-", - "A71037-", - "A71038-", - "A71039-", - "A71040-", - "C71041-", - "T71042-", - "G71043-", - "T71044-", - "A71045-", - "A71046-", - "C71047-", - "A71048-", - "C71049-", - "C71050-", - "A71051-", - "T71052-", - "A71053-", - "G71054-", - "T71055-", - "G71056-", - "T71057-", - "T71058-", - "C71059-", - "G71060-", - "G71061-", - "C71062-", - "A71063-", - "T71064-", - "C71065-", - "T71066-", - "A71067-", - "T71068-", - "A71069-", - "A71070-", - "G71071-", - "G71072-", - "A71073-", - "T71074-", - "A71075-", - "A71076-", - "T71077-", - "T71078-", - "T71079-", - "A71080-", - "C71081-", - "T71082-", - "A71083-", - "C71084-", - "T71085-", - "G71086-", - "A71087-", - "G71088-", - "T71089-", - "A71090-", - "T71091-", - "A71092-", - "C71113-", - "G71114-", - "A71115-", - "T71116-", - "A71117-", - "G71118-", - "T71119-", - "C71120-", - "T71121-", - "G71122-", - "T71123-", - "T71124-", - "A71125-", - "A71126-", - "T71127-", - "A71128-", - "A71129-", - "C71130-", - "C71131-", - "A71132-", - "A71133-", - "T71134-", - "T71172-", - "T71173-", - "A71174-", - "A71175-", - "A71176-", - "A71177-", - "A71178-", - "A71179-", - "T71180-", - "G71181-", - "G71182-", - "T71183-", - "G71184-", - "T71185-", - "T71186-", - "C71187-", - "C71188-", - "A71189-", - "G71190-", - "C71191-", - "T71192-", - "C71193-", - "G71194-", - "T71195-", - "G71196-", - "T71197-", - "G71198-", - "T71199-", - "T71200-", - "C71201-", - "T71202-", - "A71203-", - "C71204-", - "A71205-", - "T71206-", - "G71207-", - "C71208-", - "G71209-", - "G71210-", - "C71211-", - "A71212-", - "A71213-", - "A71214-", - "G71215-", - "A71216-", - "T71217-", - "A71218-", - "T71219-", - "T71220-", - "T71221-", - "C71222-", - "T71223-", - "C71224-", - "A71225-", - "C71226-", - "G71227-", - "A71228-", - "A71229-", - "C71230-", - "G71231-", - "A71232-", - "T71233-", - "A71234-", - "T71235-", - "A71236-", - "A71237-", - "A71238-", - "T71239-", - "T71240-", - "G71241-", - "A71242-", - "T71243-", - "T71244-", - "A71245-", - "T71246-", - "A71247-", - "C71248-", - "G71249-", - "A71250-", - "A71251-", - "A71252-", - "A71253-", - "A71254-", - "A71255-", - "A71256-", - "T71257-", - "C71258-", - "A71259-", - "T71260-", - "T71261-", - "A71262-", - "A71263-", - "A71264-", - "G71265-", - "G71266-", - "A71267-", - "T71268-", - "G71269-", - "T71270-", - "A71271-", - "C71272-", - "T71273-", - "A71274-", - "G71275-", - "T71276-", - "C71277-", - "A71278-", - "G71279-", - "T71280-", - "G71281-", - "T71282-", - "A71283-", - "A71284-", - "A71285-", - "G71286-", - "A71287-", - "A71288-", - "C71289-", - "G71290-", - "A71291-", - "A71292-", - "T71293-", - "G71294-", - "T71295-", - "T71296-", - "G71297-", - "T71298-", - "A71299-", - "G71300-", - "G71301-", - "T71302-", - "T71303-", - "A71304-", - "A71305-", - "A71306-", - "A71307-", - "T71308-", - "T71309-", - "A71310-", - "T71311-", - "C71312-", - "T71313-", - "A71314-", - "C71315-", - "A71316-", - "C71317-", - "A71318-", - "A71319-", - "A71320-", - "T71321-", - "A71322-", - "G71323-", - "A71324-", - "A71325-", - "C71326-", - "C71327-", - "T71328-", - "C71329-", - "A71330-", - "A71331-", - "C71332-", - "G71333-", - "T71334-", - "A71335-", - "A71336-", - "C71337-", - "T71338-", - "T71339-", - "A71340-", - "A71341-", - "C71342-", - "A71343-", - "G71344-", - "T71345-", - "G71346-", - "C71347-", - "A71348-", - "A71349-", - "C71350-", - "C71351-", - "T71352-", - "C71353-", - "T71354-", - "A71355-", - "T71356-", - "T71357-", - "G71358-", - "G71359-", - "A71360-", - "T71361-", - "A71362-", - "T71363-", - "A71364-", - "A71365-", - "A71366-", - "C71367-", - "T71368-", - "A71369-", - "A71370-", - "T71371-", - "G71372-", - "G71373-", - "A71374-", - "T71375-", - "C71376-", - "C71377-", - "G71378-", - "G71379-", - "T71380-", - "T71381-", - "A71382-", - "A71383-", - "T71384-", - "T71385-", - "T71386-", - "T71387-", - "A71388-", - "T71389-", - "C71390-", - "A71391-", - "A71392-", - "G71393-", - "A71394-", - "C71395-", - "A71396-", - "T71397-", - "A71398-", - "T71399-", - "G71400-", - "C71401-", - "G71402-", - "C71403-", - "C71404-", - "T71405-", - "A71406-", - "G71407-", - "A71408-", - "G71409-", - "G71410-", - "T71411-", - "T71412-", - "C71413-", - "T71414-", - "A71415-", - "T71416-", - "T71417-", - "A71418-", - "T71419-", - "T71420-", - "T71421-", - "T71422-", - "T71423-", - "A71424-", - "T71425-", - "T71426-", - "T71500-", - "A71501-", - "T71502-", - "T71503-", - "A71504-", - "T71505-", - "C71506-", - "G71507-", - "G71508-", - "A71509-", - "A71510-", - "C71511-", - "A71512-", - "C71513-", - "T71514-", - "T71515-", - "G71516-", - "G71517-", - "T71518-", - "A71519-", - "G71520-", - "T71521-", - "T71522-", - "G71523-", - "A71524-", - "A71525-", - "T71526-", - "C71527-", - "T71528-", - "A71529-", - "C71530-", - "C71531-", - "T71532-", - "A71533-", - "T71534-", - "A71535-", - "G71536-", - "A71537-", - "A71538-", - "A71539-", - "A71540-", - "G71541-", - "G71542-", - "A71543-", - "G71544-", - "T71545-", - "T71546-", - "A71547-", - "G71548-", - "A71549-", - "A71550-", - "T71551-", - "A71552-", - "G71553-", - "T71554-", - "C71555-", - "C71556-", - "C71557-", - "A71558-", - "T71559-", - "T71560-", - "G71561-", - "G71562-", - "A71563-", - "T71564-", - "A71565-", - "G71566-", - "A71567-", - "T71568-", - "T71569-", - "T71570-", - "T71571-", - "T71572-", - "T71573-", - "G71574-", - "A71575-", - "A71576-", - "G71577-", - "G71578-", - "A71579-", - "T71580-", - "A71581-", - "T71582-", - "C71583-", - "T71584-", - "T71585-", - "A71586-", - "G71587-", - "T71588-", - "G71589-", - "C71590-", - "A71591-", - "A71592-", - "A71593-", - "A71594-", - "G71595-", - "T71596-", - "A71597-", - "T71598-", - "A71599-", - "C71600-", - "A71601-", - "T71602-", - "G71603-", - "T71604-", - "T71605-", - "A71606-", - "G71607-", - "A71608-", - "G71609-", - "A71610-", - "A71611-", - "T71612-", - "A71613-", - "T71614-", - "T71615-", - "C71616-", - "A71617-", - "A71618-", - "G71619-", - "T71620-", - "T71621-", - "A71622-", - "T71623-", - "G71624-", - "A71625-", - "A71626-", - "A71627-", - "A71628-", - "T71629-", - "A71630-", - "G71631-", - "C71632-", - "A71633-", - "G71634-", - "C71635-", - "T71674-", - "T71675-", - "G71676-", - "G71677-", - "A71701-", - "A71702-", - "T71703-", - "T71704-", - "G71705-", - "G71706-", - "T71707-", - "A71708-", - "G71709-", - "C71710-", - "T71711-", - "G71712-", - "A71713-", - "A71714-", - "T71715-", - "G71716-", - "T71717-", - "T71718-", - "A71719-", - "T71720-", - "A71721-", - "A71722-", - "A71723-", - "A71724-", - "A71725-", - "T71726-", - "G71727-", - "C71728-", - "C71729-", - "G71730-", - "G71731-", - "T71732-", - "A71733-", - "T71734-", - "T71735-", - "G71736-", - "A71737-", - "T71738-", - "A71739-", - "C71740-", - "A71741-", - "T71742-", - "C71743-", - "G71744-", - "T71745-", - "C71746-", - "T71747-", - "A71748-", - "A71749-", - "A71750-", - "C71751-", - "G71752-", - "A71753-", - "A71754-", - "T71755-", - "A71756-", - "T71757-", - "T71758-", - "A71759-", - "G71760-", - "G71761-", - "T71762-", - "A71763-", - "A71764-", - "A71765-", - "G71766-", - "A71767-", - "T71768-", - "A71769-", - "T71770-", - "T71771-", - "T71772-", - "T71773-", - "T71774-", - "C71775-", - "T71776-", - "G71777-", - "A71778-", - "G71779-", - "C71780-", - "C71781-", - "A71782-", - "A71783-", - "A71784-", - "A71785-", - "C71786-", - "T71787-", - "T71788-", - "T71789-", - "A71790-", - "C71791-", - "A71792-", - "G71793-", - "A71794-", - "T71795-", - "G71796-", - "A71797-", - "T71798-", - "A71799-", - "A71800-", - "T71801-", - "A71802-", - "G71803-", - "A71804-", - "T71805-", - "C71855-", - "T71908-", - "T71909-", - "C71910-", - "T71911-", - "T71912-", - "T71913-", - "T71914-", - "T71915-", - "C71916-", - "T71917-", - "T71918-", - "A71919-", - "A71920-", - "C71921-", - "G71922-", - "T71923-", - "T71924-", - "G71925-", - "T71926-", - "T71927-", - "T71928-", - "G71929-", - "C71930-", - "C71931-", - "A71932-", - "T71933-", - "C71934-", - "A71935-", - "C71936-", - "T71937-", - "C71938-", - "T71939-", - "C71940-", - "A71941-", - "T71942-", - "A71943-", - "A71944-", - "T71945-", - "G71946-", - "T71947-", - "A71948-", - "A71949-", - "A71950-", - "G71951-", - "A71952-", - "T71953-", - "A71954-", - "T71955-", - "T71956-", - "C71957-", - "T71958-", - "A71959-", - "A71960-", - "A71961-", - "A71962-", - "T71963-", - "G71964-", - "G71965-", - "T71966-", - "A71967-", - "A71968-", - "A71969-", - "C71970-", - "T71971-", - "T71972-", - "T71973-", - "T71974-", - "G71975-", - "C71976-", - "A71977-", - "T71978-", - "A71979-", - "T71980-", - "C71981-", - "G71982-", - "G71983-", - "A71984-", - "T71985-", - "G71986-", - "C71987-", - "A71988-", - "G71989-", - "A71990-", - "A71991-", - "A71992-", - "T71993-", - "T71994-", - "G71995-", - "G71996-", - "T71997-", - "A71998-", - "T71999-", - "A72000-", - "A72001-", - "A72002-", - "T72003-", - "G72004-", - "T72005-", - "T72006-", - "G72007-", - "T72008-", - "A72009-", - "A72010-", - "T72011-", - "T72012-", - "G72013-", - "T72014-", - "A72015-", - "T72016-", - "T72017-", - "A72018-", - "T72019-", - "T72020-", - "T72021-", - "C72022-", - "C72023-", - "C72024-", - "G72025-", - "T72026-", - "C72027-", - "A72028-", - "A72029-", - "T72030-", - "G72031-", - "G72032-", - "A72033-", - "C72034-", - "T72035-", - "A72036-", - "G72037-", - "T72038-", - "C72039-", - "A72040-", - "C72041-", - "A72042-", - "G72043-", - "C72044-", - "T72045-", - "C72046-", - "C72047-", - "A72048-", - "T72049-", - "C72050-", - "A72051-", - "G72052-", - "T72053-", - "T72054-", - "T72055-", - "T72056-", - "A72057-", - "T72058-", - "A72059-", - "T72060-", - "C72061-", - "C72062-", - "T72063-", - "T72064-", - "T72065-", - "A72066-", - "G72067-", - "A72068-", - "G72069-", - "T72070-", - "A72071-", - "T72072-", - "T72073-", - "T72074-", - "C72075-", - "T72076-", - "C72077-", - "A72078-", - "C72079-", - "T72080-", - "C72081-", - "G72082-", - "T72083-", - "G72084-", - "T72085-", - "C72086-", - "T72087-", - "A72088-", - "G72089-", - "C72090-", - "A72091-", - "T72092-", - "T72093-", - "C72094-", - "T72095-", - "A72096-", - "G72097-", - "A72098-", - "G72099-", - "C72100-", - "A72101-", - "T72102-", - "T72103-", - "C72104-", - "C72105-", - "A72106-", - "T72107-", - "G72108-", - "A72109-", - "T72110-", - "C72111-", - "T72112-", - "G72113-", - "T72114-", - "T72115-", - "T72116-", - "A72117-", - "T72118-", - "C72119-", - "G72120-", - "T72121-", - "T72122-", - "G72123-", - "A72124-", - "T72125-", - "A72126-", - "T72127-", - "T72128-", - "G72129-", - "G72130-", - "C72131-", - "C72132-", - "G72133-", - "G72134-", - "A72135-", - "A72136-", - "A72137-", - "G72138-", - "A72139-", - "T72140-", - "A72141-", - "G72142-", - "A72143-", - "T72144-", - "T72145-", - "T72146-", - "T72147-", - "T72148-", - "T72149-", - "A72150-", - "T72151-", - "T72152-", - "T72153-", - "T72154-", - "T72155-", - "T72156-", - "A72157-", - "T72158-", - "T72159-", - "A72160-", - "T72161-", - "A72162-", - "T72163-", - "T72164-", - "A72165-", - "C72166-", - "T72167-", - "A72168-", - "T72169-", - "T72170-", - "G72171-", - "G72172-", - "C72173-", - "A72174-", - "A72175-", - "T72176-", - "T72177-", - "G72178-", - "T72179-", - "A72180-", - "G72181-", - "A72182-", - "T72183-", - "A72184-", - "T72185-", - "A72186-", - "A72187-", - "C72188-", - "T72189-", - "T72190-", - "C72191-", - "T72192-", - "G72193-", - "G72194-", - "T72195-", - "A72196-", - "A72197-", - "A72198-", - "T72199-", - "A72200-", - "T72201-", - "T72202-", - "T72203-", - "T72204-", - "T72205-", - "C72206-", - "T72207-", - "A72208-", - "C72209-", - "C72210-", - "T72211-", - "T72212-", - "T72213-", - "T72214-", - "C72215-", - "A72216-", - "A72217-", - "T72218-", - "C72219-", - "T72220-", - "C72221-", - "T72222-", - "T72223-", - "C72224-", - "T72225-", - "A72226-", - "T72227-", - "T72228-", - "T72229-", - "T72230-", - "C72231-", - "A72232-", - "A72233-", - "G72234-", - "C72235-", - "C72236-", - "G72237-", - "G72238-", - "C72239-", - "T72240-", - "A72241-", - "T72242-", - "A72243-", - "T72244-", - "A72245-", - "T72246-", - "T72247-", - "C72248-", - "T72249-", - "G72250-", - "C72251-", - "T72252-", - "A72253-", - "T72254-", - "A72255-", - "T72256-", - "T72257-", - "G72258-", - "T72259-", - "T72260-", - "A72261-", - "C72262-", - "T72263-", - "A72264-", - "G72265-", - "T72266-", - "A72267-", - "T72268-", - "C72269-", - "A72270-", - "A72271-", - "T72272-", - "A72273-", - "C72274-", - "C72275-", - "T72276-", - "T72277-", - "T72278-", - "T72279-", - "C72280-", - "T72281-", - "G72282-", - "G72283-", - "C72284-", - "T72285-", - "A72286-", - "A72287-", - "G72288-", - "A72289-", - "A72290-", - "G72291-", - "T72292-", - "C72293-", - "A72294-", - "T72295-", - "A72296-", - "T72297-", - "G72298-", - "T72299-", - "G72300-", - "G72301-", - "T72302-", - "A72303-", - "T72304-", - "T72305-", - "C72306-", - "A72307-", - "C72308-", - "T72309-", - "A72310-", - "T72311-", - "A72312-", - "T72313-", - "C72314-", - "A72315-", - "G72316-", - "T72317-", - "T72318-", - "T72319-", - "T72320-", - "A72321-", - "A72322-", - "C72323-", - "T72324-", - "G72325-", - "G72326-", - "T72327-", - "A72328-", - "G72329-", - "T72330-", - "T72331-", - "C72332-", - "C72333-", - "A72334-", - "T72335-", - "T72336-", - "A72337-", - "G72338-", - "C72339-", - "C72340-", - "T72341-", - "T72342-", - "T72343-", - "C72344-", - "C72345-", - "A72346-", - "C72347-", - "T72348-", - "T72349-", - "C72350-", - "T72351-", - "G72352-", - "C72353-", - "A72354-", - "G72355-", - "A72356-", - "A72357-", - "T72358-", - "A72359-", - "A72360-", - "T72361-", - "T72362-", - "A72363-", - "G72364-", - "A72365-", - "A72366-", - "A72367-", - "T72368-", - "T72369-", - "G72370-", - "G72371-", - "T72372-", - "T72373-", - "C72374-", - "T72375-", - "T72376-", - "T72377-", - "A72378-", - "C72379-", - "C72380-", - "A72381-", - "G72382-", - "A72383-", - "A72384-", - "A72385-", - "A72386-", - "T72387-", - "C72388-", - "C72389-", - "A72390-", - "G72391-", - "C72392-", - "-178823C", - "-194549A" - ], - "OPG002": [ - "-31X", - "*350X" - ], - "OPG080": [ - "X78-" - ], - "OPG089": [ - "S307X", - "Y308-", - "I309X", - "F321X", - "Y335X", - "L336-", - "E337-", - "S338-", - "V339-", - "P340X", - "A348-", - "L349-", - "E350-", - "P351-", - "R352-", - "S358X", - "E359X", - "Y366X", - "D368X", - "F369-", - "E370-", - "N371-", - "T372-", - "K373-", - "S374X", - "F386X", - "G387-", - "Y388-", - "S389-", - "N390-", - "E391-", - "N392-", - "C393-", - "N394-", - "T395-", - "I396-", - "V397-", - "F398-", - "G399-", - "I400-", - "Y401-", - "K402-", - "D403-", - "N404-", - "L405-", - "L406-", - "L407-", - "S408-", - "I409-", - "N416X", - "D417-", - "S418-", - "L419-", - "L420-", - "I421-", - "T422-", - "N423-", - "*435X" - ], - "OPG090": [ - "M1-", - "V2-", - "F3-", - "Q4-", - "L5-", - "V6-", - "C7-", - "S8-", - "T9-", - "C10-", - "G11-", - "K12-", - "D13-", - "I14-", - "S15-", - "H16-", - "E17-", - "R18-", - "Y19-", - "K20-", - "L21-", - "I22-", - "I23-", - "R24-", - "K25-", - "K26-", - "S27-", - "L28-", - "K29-", - "D30-", - "V31-", - "L32-", - "V33-", - "S34-", - "V35-", - "K36-", - "N37-", - "E38-", - "C39-", - "C40-", - "R41-", - "L42-", - "K43-", - "L44-", - "S45-", - "T46-", - "Q47-", - "I48-", - "E49-", - "P50-", - "Q51-", - "R52-", - "N53-", - "L54-", - "T55-", - "V56-", - "Q57-", - "P58-", - "L59-", - "L60-", - "D61-", - "I62-", - "N63-", - "*64-" - ], - "OPG091": [ - "M1-", - "D2-", - "P3-", - "V4-", - "N5-", - "F6-", - "I7-", - "K8-", - "T9-", - "Y10-", - "A11-", - "P12-", - "R13-", - "G14-", - "S15-", - "I16-", - "I17-", - "F18-", - "I19-", - "L44X", - "L45-", - "S46-", - "E47-", - "H48-", - "L49-", - "V50-", - "V51-", - "E52-", - "S53-", - "T54-", - "Y55-", - "R56-", - "K57-", - "G58-", - "V59-", - "R60-", - "I61-", - "V62-", - "P63-", - "L64-", - "D65-", - "R66-", - "F67-", - "F68-", - "E69-", - "G70-", - "Y71-", - "L72-", - "S73-", - "A74-", - "K75-", - "V76-", - "Y77-", - "M78-", - "L79-", - "E80-", - "N81-", - "I82-", - "Q83-", - "V84-", - "M85-", - "K86-", - "I87-", - "A88-", - "A89X", - "F102X", - "G103X", - "K111X", - "L112-", - "V113-", - "A114-", - "E115-", - "C116-", - "Y117-", - "K118-", - "N119-", - "A120-", - "G121-", - "I122-", - "D123-", - "T124-", - "S125-", - "S126-", - "K127-", - "R128-", - "I129-", - "L130-", - "G131-", - "K132-", - "D133-", - "I134-", - "F135-", - "L136-", - "S137-", - "Q138-", - "N139-", - "F140-", - "T141-", - "D142-", - "D143-", - "N144-", - "R145-", - "W146X", - "Y162X", - "*166X" - ], - "OPG092": [ - "A186-", - "G187-", - "F188-", - "S189-", - "G190-", - "K191-", - "E192-", - "P193-", - "I194-", - "S195-", - "N196-", - "Y197-", - "S198-", - "A199-", - "E200-", - "V201-", - "E202-", - "R203-", - "L204-", - "M205-", - "E206-", - "L207-", - "P208-", - "V209-", - "K210-", - "T211-", - "D212-", - "I213-", - "V214-", - "N215-", - "T216-", - "T217-", - "Y218-", - "D219-", - "F220-", - "L221-", - "A222-", - "R223-", - "K224-", - "G225-", - "I226-", - "D227-", - "T228-", - "S229-", - "N230-", - "N231-", - "I232-", - "A233-", - "E234-", - "Y235-", - "I236-", - "A237-", - "G238-", - "L239-", - "K240-", - "I241-", - "E242-", - "E243-", - "I244-", - "E245-", - "K246-", - "V247-", - "E248-", - "K249-", - "Y250-", - "L251-", - "P252-", - "E253-", - "V254-", - "I255-", - "S256-", - "T257-", - "I258-", - "A259-", - "N260-", - "S261-", - "N262-", - "I263-", - "I264-", - "K265-", - "N266-", - "K267-", - "K268-", - "S269-", - "I270-", - "F271-", - "P272-", - "A273-", - "N274-", - "I275-", - "N276-", - "D277-", - "K278-", - "Q279-", - "I280-", - "M281-", - "E282-", - "C283-", - "S284-", - "R285-", - "M286-", - "L287-", - "D288-", - "T289-", - "S290-", - "E291-", - "K292-", - "Y293-", - "S294-", - "K295-", - "G296-", - "Y297-", - "K298-", - "T299-", - "D300-", - "G301-", - "A302-", - "V303-", - "T304-", - "S305-", - "P306-", - "L307-", - "T308-", - "G309-", - "N310-", - "N311-", - "T312-", - "I313-", - "T314-", - "T315-", - "F316-", - "I317-", - "P318-", - "I319-", - "S320-", - "A321-", - "S322-", - "D323-", - "M324-", - "Q325-", - "K326-", - "F327-", - "T328-", - "I329-", - "L330-", - "E331-", - "Y332-", - "L333-", - "Y334-", - "I335-", - "M336-", - "R337-", - "V338-", - "M339-", - "A340-", - "N341-", - "N342-", - "V343-", - "K344-", - "K345-", - "K346-", - "N347X", - "V365X", - "*372X" - ] - }, - "labels": { - "aa": "OPG002: -31X, *350X; OPG080: X78-; OPG089: S307X, Y308-, I309X, F321X, Y335X, L336-, E337-, S338-, V339-, P340X, A348-, L349-, E350-, P351-, R352-, S358X, E359X, Y366X, D368X, F369-, E370-, N371-, T372-, K373-, S374X, F386X, G387-, Y388-, S389-, N390-, E391-, N392-, C393-, N394-, T395-, I396-, V397-, F398-, G399-, I400-, Y401-, K402-, D403-, N404-, L405-, L406-, L407-, S408-, I409-, N416X, D417-, S418-, L419-, L420-, I421-, T422-, N423-, *435X; OPG090: M1-, V2-, F3-, Q4-, L5-, V6-, C7-, S8-, T9-, C10-, G11-, K12-, D13-, I14-, S15-, H16-, E17-, R18-, Y19-, K20-, L21-, I22-, I23-, R24-, K25-, K26-, S27-, L28-, K29-, D30-, V31-, L32-, V33-, S34-, V35-, K36-, N37-, E38-, C39-, C40-, R41-, L42-, K43-, L44-, S45-, T46-, Q47-, I48-, E49-, P50-, Q51-, R52-, N53-, L54-, T55-, V56-, Q57-, P58-, L59-, L60-, D61-, I62-, N63-, *64-; OPG091: M1-, D2-, P3-, V4-, N5-, F6-, I7-, K8-, T9-, Y10-, A11-, P12-, R13-, G14-, S15-, I16-, I17-, F18-, I19-, L44X, L45-, S46-, E47-, H48-, L49-, V50-, V51-, E52-, S53-, T54-, Y55-, R56-, K57-, G58-, V59-, R60-, I61-, V62-, P63-, L64-, D65-, R66-, F67-, F68-, E69-, G70-, Y71-, L72-, S73-, A74-, K75-, V76-, Y77-, M78-, L79-, E80-, N81-, I82-, Q83-, V84-, M85-, K86-, I87-, A88-, A89X, F102X, G103X, K111X, L112-, V113-, A114-, E115-, C116-, Y117-, K118-, N119-, A120-, G121-, I122-, D123-, T124-, S125-, S126-, K127-, R128-, I129-, L130-, G131-, K132-, D133-, I134-, F135-, L136-, S137-, Q138-, N139-, F140-, T141-, D142-, D143-, N144-, R145-, W146X, Y162X, *166X; OPG092: A186-, G187-, F188-, S189-, G190-, K191-, E192-, P193-, I194-, S195-, N196-, Y197-, S198-, A199-, E200-, V201-, E202-, R203-, L204-, M205-, E206-, L207-, P208-, V209-, K210-, T211-, D212-, I213-, V214-, N215-, T216-, T217-, Y218-, D219-, F220-, L221-, A222-, R223-, K224-, G225-, I226-, D227-, T228-, S229-, N230-, N231-, I232-, A233-, E234-, Y235-, I236-, A237-, G238-, L239-, K240-, I241-, E242-, E243-, I244-, E245-, K246-, V247-, E248-, K249-, Y250-, L251-, P252-, E253-, V254-, I255-, S256-, T257-, I258-, A259-, N260-, S261-, N262-, I263-, I264-, K265-, N266-, K267-, K268-, S269-, I270-, F271-, P272-, A273-, N274-, I275-, N276-, D277-, K278-, Q279-, I280-, M281-, E282-, C283-, S284-, R285-, M286-, L287-, D288-, T289-, S290-, E291-, K292-, Y293-, S294-, K295-, G296-, Y297-, K298-, T299-, D300-, G301-, A302-, V303-, T304-, S305-, P306-, L307-, T308-, G309-, N310-, N311-, T312-, I313-, T314-, T315-, F316-, I317-, P318-, I319-, S320-, A321-, S322-, D323-, M324-, Q325-, K326-, F327-, T328-, I329-, L330-, E331-, Y332-, L333-, Y334-, I335-, M336-, R337-, V338-, M339-, A340-, N341-, N342-, V343-, K344-, K345-, K346-, N347X, V365X, *372X" - } - } - }, - { - "name": "23022023_anal", - "node_attrs": { - "div": 7, - "author": { - "author": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K.", - "value": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K." - }, - "strain_original": { - "value": "23022023_anal" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ672578" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-02-23" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T2662-", - "A47692-", - "A48019-", - "C48020-", - "T61624-", - "T61625-", - "G61626-", - "A61627-", - "G61628-", - "C61629-", - "A61674-", - "A61675-", - "T61676-", - "C61677-", - "G61678-", - "A61680-", - "G61681-", - "A61682-", - "A61683-", - "T61684-", - "G61685-", - "T61686-", - "T61687-", - "T61688-", - "C61689-", - "C61690-", - "C61691-", - "A61692-", - "T61693-", - "T61694-", - "T61695-", - "T61696-", - "T61697-", - "A61698-", - "G61699-", - "G61700-", - "A61701-", - "T61702-", - "T61703-", - "A61704-", - "A61705-", - "C61706-", - "A61707-", - "T61708-", - "A61709-", - "G61710-", - "A61738-", - "A61739-", - "T61740-", - "A61741-", - "G61742-", - "A61762-", - "G61763-", - "A61764-", - "T61765-", - "T61766-", - "T61767-", - "G61768-", - "A61769-", - "G61790-", - "G61795-", - "A61797-", - "T61798-", - "A61799-", - "A61800-", - "T61801-", - "C61802-", - "C61803-", - "G61804-", - "G61805-", - "A61806-", - "T61807-", - "G61808-", - "T61809-", - "T61810-", - "G61811-", - "T61812-", - "G61813-", - "T61814-", - "A62036-", - "A62038-", - "A62039-", - "A62040-", - "T62042-", - "G62357-", - "C62361-", - "T62362-", - "T62371-", - "T62372-", - "T62374-", - "T62375-", - "G88521-", - "A88522-", - "T88523-", - "C88524-", - "T88525-", - "C88526-", - "T88527-", - "A88528-", - "T88529-", - "A88530-", - "A88531-", - "T88532-", - "A88533-", - "T88534-", - "C88535-", - "T88536-", - "A88537-", - "G88538-", - "T88539-", - "T88540-", - "T88541-", - "C88542-", - "T88543-", - "T88544-", - "G88545-", - "C88546-", - "G88547-", - "T88548-", - "T88549-", - "T88550-", - "C88551-", - "A88552-", - "C88553-", - "A88554-", - "A88555-", - "A88556-", - "C88557-", - "A88558-", - "C88559-", - "A88560-", - "G88561-", - "G88562-", - "C88563-", - "T88564-", - "C88565-", - "G88566-", - "T88567-", - "C88568-", - "T88569-", - "C88570-", - "T88571-", - "C88572-", - "G88573-", - "C88574-", - "G88575-", - "A88576-", - "T88577-", - "G88578-", - "A88579-", - "G88580-", - "A88581-", - "T88582-", - "C88583-", - "T88584-", - "G88585-", - "T88586-", - "A88587-", - "T88588-", - "A88589-", - "G88590-", - "T88591-", - "A88592-", - "A88593-", - "C88594-", - "T88595-", - "A88596-", - "T88597-", - "G88598-", - "T88599-", - "A88600-", - "A88601-", - "A88602-", - "T88603-", - "G88604-", - "A88605-", - "T88606-", - "A88607-", - "A88608-", - "C88609-", - "T88610-", - "A88611-", - "G88612-", - "A88613-", - "T88614-", - "A88615-", - "G88616-", - "A88617-", - "A88618-", - "A88619-", - "G88620-", - "A88621-", - "T88622-", - "G88623-", - "T88624-", - "A88625-", - "G88626-", - "C88627-", - "T88628-", - "A88629-", - "T88630-", - "A88631-", - "T88632-", - "A88633-", - "G88634-", - "A88635-", - "T88636-", - "G88637-", - "A88638-", - "C88639-", - "G88640-", - "A88641-", - "T88642-", - "C88643-", - "C88644-", - "T88645-", - "T88646-", - "T88647-", - "A88648-", - "A88649-", - "G88650-", - "A88651-", - "G88652-", - "A88653-", - "G88654-", - "G88655-", - "T88656-", - "A88657-", - "T88658-", - "A88659-", - "A88660-", - "T88661-", - "A88662-", - "A88663-", - "C88664-", - "T88665-", - "T88666-", - "T88667-", - "A88668-", - "C88669-", - "C88670-", - "C88671-", - "C88672-", - "A88673-", - "A88674-", - "T88675-", - "C88676-", - "A88677-", - "G88678-", - "A88679-", - "T88680-", - "A88681-", - "G88682-", - "A88683-", - "C88684-", - "T88685-", - "G88686-", - "T88687-", - "T88688-", - "G88689-", - "T88690-", - "T88691-", - "A88692-", - "T88693-", - "G88694-", - "G88695-", - "T88696-", - "C88697-", - "T88698-", - "T88699-", - "C88700-", - "G88701-", - "G88702-", - "A88703-", - "A88704-", - "A88705-", - "A88706-", - "A88707-", - "G88708-", - "A88709-", - "A88710-", - "T88711-", - "T88712-", - "T88713-", - "T88714-", - "T88715-", - "A88716-", - "T88717-", - "A88718-", - "A88719-", - "A88720-", - "T88721-", - "T88722-", - "T88723-", - "T88724-", - "T88725-", - "C88726-", - "C88727-", - "A88728-", - "G88729-", - "T88730-", - "A88731-", - "T88732-", - "T88733-", - "T88734-", - "T88735-", - "C88736-", - "T88737-", - "A88738-", - "A88739-", - "A88740-", - "T88741-", - "A88742-", - "T88743-", - "A88744-", - "C88745-", - "G88746-", - "T88747-", - "A88748-", - "C88749-", - "T88750-", - "T88751-", - "G88752-", - "A88753-", - "T88754-", - "A88755-", - "T88756-", - "C88757-", - "T88758-", - "A88759-", - "A88760-", - "G88761-", - "A88762-", - "A88763-", - "A88764-", - "T88765-", - "C88766-", - "C88767-", - "T88768-", - "T88769-", - "A88770-", - "A88771-", - "T88772-", - "A88773-", - "A88774-", - "T88775-", - "A88776-", - "A88777-", - "T88778-", - "A88779-", - "G88780-", - "G88781-", - "A88782-", - "A88783-", - "T88784-", - "G88785-", - "G88786-", - "A88787-", - "T88788-", - "A88789-", - "A88790-", - "T88791-", - "C88792-", - "C88793-", - "G88794-", - "T88795-", - "C88796-", - "T88797-", - "A88798-", - "T88799-", - "T88800-", - "T88801-", - "T88802-", - "A88803-", - "T88804-", - "A88805-", - "A88806-", - "A88807-", - "G88808-", - "A88809-", - "A88810-", - "A88811-", - "T88812-", - "A88813-", - "C88814-", - "A88815-", - "T88816-", - "A88817-", - "T88818-", - "C88819-", - "G88820-", - "C88821-", - "A88822-", - "T88823-", - "A88824-", - "T88825-", - "T88826-", - "A88827-", - "T88828-", - "A88829-", - "C88830-", - "T88831-", - "T88832-", - "T88833-", - "T88834-", - "T88835-", - "T88836-", - "T88837-", - "T88838-", - "G88839-", - "G88840-", - "A88841-", - "A88842-", - "A88843-", - "T88844-", - "T88845-", - "G88846-", - "G88847-", - "A88848-", - "A88849-", - "T88850-", - "A88851-", - "C88852-", - "C88853-", - "G88854-", - "A88855-", - "T88856-", - "G88857-", - "T88858-", - "G88859-", - "T88860-", - "C88861-", - "T88862-", - "A88863-", - "C88864-", - "A88865-", - "T88866-", - "A88867-", - "A88868-", - "A88869-", - "T88870-", - "A88871-", - "C88872-", - "G88873-", - "C88874-", - "A88875-", - "A88876-", - "A88877-", - "G88878-", - "T88879-", - "C88880-", - "T88881-", - "A88882-", - "A88883-", - "A88884-", - "T88885-", - "A88886-", - "T88887-", - "T88888-", - "T88889-", - "T88890-", - "T88891-", - "T88892-", - "A88893-", - "G88894-", - "A88895-", - "G88896-", - "A88897-", - "A88898-", - "T88899-", - "C88900-", - "T88901-", - "T88902-", - "A88903-", - "G88904-", - "T88905-", - "T88906-", - "G88907-", - "G88908-", - "T88909-", - "C88910-", - "C88911-", - "A88912-", - "A88913-", - "A88914-", - "T88915-", - "T88916-", - "C88917-", - "T88918-", - "T88919-", - "T88920-", - "T88921-", - "C88922-", - "C88923-", - "A88924-", - "A88925-", - "G88926-", - "T88927-", - "A88928-", - "C88929-", - "G88930-", - "G88931-", - "T88932-", - "A88933-", - "A88934-", - "T88935-", - "A88936-", - "G88937-", - "A88938-", - "T88939-", - "T88940-", - "T88941-", - "T88942-", - "T88943-", - "C88944-", - "A88945-", - "T88946-", - "A88947-", - "T88948-", - "T88949-", - "G88950-", - "A88951-", - "A88952-", - "C88953-", - "G88954-", - "G88955-", - "T88956-", - "A88957-", - "T88958-", - "C88959-", - "T88960-", - "T88961-", - "C88962-", - "T88963-", - "T88964-", - "G88965-", - "A88966-", - "T88967-", - "C88968-", - "T88969-", - "C88970-", - "T88971-", - "G88972-", - "G88973-", - "T88974-", - "T88975-", - "C88976-", - "T88977-", - "A88978-", - "A88979-", - "T88980-", - "T88981-", - "C88982-", - "C88983-", - "G88984-", - "C88985-", - "A88986-", - "T88987-", - "T88988-", - "A88989-", - "A88990-", - "A88991-", - "T88992-", - "G88993-", - "A88994-", - "T88995-", - "G88996-", - "A88997-", - "A88998-", - "A88999-", - "C89000-", - "T89001-", - "A89002-", - "A89003-", - "G89004-", - "T89005-", - "C89006-", - "A89007-", - "C89008-", - "T89009-", - "A89010-", - "T89011-", - "T89012-", - "T89013-", - "T89014-", - "T89015-", - "A89016-", - "T89017-", - "A89018-", - "A89019-", - "C89020-", - "T89021-", - "A89022-", - "A89023-", - "C89024-", - "G89025-", - "A89026-", - "T89027-", - "T89028-", - "A89029-", - "C89030-", - "A89031-", - "T89032-", - "C89033-", - "A89034-", - "C89035-", - "C89036-", - "T89037-", - "C89038-", - "T89039-", - "A89040-", - "A89041-", - "C89042-", - "A89043-", - "T89044-", - "C89045-", - "A89046-", - "T89047-", - "C89048-", - "A89049-", - "T89050-", - "T89051-", - "T89052-", - "A89053-", - "C89054-", - "C89055-", - "A89056-", - "G89057-", - "G89058-", - "A89059-", - "T89060-", - "A89061-", - "C89062-", - "T89063-", - "G89064-", - "A89065-", - "T89066-", - "C89067-", - "T89068-", - "T89069-", - "C89070-", - "T89071-", - "T89072-", - "T89073-", - "T89074-", - "G89075-", - "T89076-", - "C89077-", - "G89078-", - "T89079-", - "A89080-", - "A89081-", - "A89082-", - "T89083-", - "A89084-", - "C89085-", - "A89086-", - "T89087-", - "G89088-", - "T89089-", - "C89090-", - "T89091-", - "A89092-", - "A89093-", - "T89094-", - "G89095-", - "T89096-", - "G89097-", - "T89098-", - "T89099-", - "A89103-", - "A89104-", - "A89105-", - "A89106-", - "A89107-", - "G89108-", - "A89109-", - "T89110-", - "C89111-", - "A89112-", - "T89113-", - "A89114-", - "C89115-", - "A89116-", - "A89117-", - "G89118-", - "T89119-", - "T89120-", - "A89121-", - "T89122-", - "A89123-", - "C89124-", - "G89125-", - "T89126-", - "C89127-", - "A89128-", - "T89129-", - "T89130-", - "T89131-", - "C89132-", - "A89133-", - "T89134-", - "C89135-", - "T89136-", - "G89137-", - "T89138-", - "A89139-", - "G89140-", - "T89141-", - "A89142-", - "T89143-", - "T89144-", - "T89152-", - "A89156-", - "G89157-", - "G89158-", - "A89159-", - "T89160-", - "A89161-", - "A89162-", - "A89163-", - "C89164-", - "T89165-", - "T89168-", - "A89169-", - "T89171-", - "A89172-", - "A89173-", - "T89174-", - "C89175-", - "T89176-", - "C89177-", - "T89178-", - "T89179-", - "C89186-", - "A89187-", - "G89188-", - "T89189-", - "C89190-", - "T89191-", - "G89192-", - "T89193-", - "T89194-", - "C89195-", - "A89196-", - "A89197-", - "A89198-", - "T89199-", - "T89200-", - "T89201-", - "A89202-", - "T89203-", - "A89204-", - "T89205-", - "C89206-", - "C89207-", - "T89208-", - "A89209-", - "T89210-", - "A89211-", - "T89212-", - "A89213-", - "T89214-", - "G89215-", - "A89217-", - "A89218-", - "A89226-", - "A89227-", - "A89230-", - "T89236-", - "A89238-", - "T89239-", - "C89240-", - "A89241-", - "T89242-", - "C89243-", - "C89244-", - "G89245-", - "C89246-", - "G89247-", - "T89248-", - "C89249-", - "A89250-", - "A89251-", - "T89252-", - "A89253-", - "T89254-", - "T89255-", - "C89256-", - "T89257-", - "G89258-", - "T89259-", - "T89260-", - "C89261-", - "T89262-", - "A89263-", - "T89264-", - "C89265-", - "G89266-", - "T89267-", - "A89268-", - "G89269-", - "T89270-", - "G89271-", - "T89272-", - "A89273-", - "T89274-", - "A89275-", - "A89276-", - "C89277-", - "A89278-", - "A89279-", - "T89280-", - "C89281-", - "T89282-", - "T89283-", - "A89284-", - "T89285-", - "A89286-", - "T89287-", - "T89289-", - "T89290-", - "T89292-", - "T89293-", - "C89294-", - "T89295-", - "G89296-", - "T89297-", - "G89298-", - "A89299-", - "T89300-", - "A89301-", - "G89302-", - "T89303-", - "C89304-", - "G89305-", - "A89306-", - "T89307-", - "A89308-", - "C89309-", - "G89310-", - "T89311-", - "T89312-", - "A89313-", - "T89314-", - "A89315-", - "A89316-", - "A89317-", - "G89318-", - "G89319-", - "T89320-", - "T89321-", - "G89322-", - "A89323-", - "T89324-", - "A89325-", - "A89326-", - "A89331-", - "A89332-", - "T89333-", - "A89334-", - "T89335-", - "T89336-", - "T89337-", - "T89338-", - "T89339-", - "A89340-", - "T89341-", - "T89342-", - "T89343-", - "C89344-", - "G89345-", - "T89346-", - "G89347-", - "A89348-", - "A89349-", - "A89350-", - "T89351-", - "A89352-", - "A89353-", - "A89354-", - "G89355-", - "T89356-", - "C89357-", - "A89358-", - "T89359-", - "T89360-", - "G89361-", - "T89362-", - "A89363-", - "G89364-", - "G89365-", - "A89366-", - "T89367-", - "T89368-", - "T89369-", - "T89370-", - "G89371-", - "G89372-", - "T89395-", - "A89396-", - "T89400-", - "A89404-", - "T89405-", - "T89406-", - "T89407-", - "T89408-", - "G89415-", - "A89416-", - "T89417-", - "C89418-", - "C89420-", - "A89421-", - "A89422-", - "T89423-", - "T89424-", - "A89425-", - "A89426-", - "A89427-", - "A89428-", - "A89430-", - "T89432-", - "C89433-", - "T89434-", - "C89435-", - "T89436-", - "T89437-", - "T89438-", - "A89439-", - "G89440-", - "A89441-", - "G89442-", - "T89443-", - "C89444-", - "C89445-", - "A89446-", - "T89447-", - "T89448-", - "T89449-", - "A89450-", - "A89451-", - "A89452-", - "G89453-", - "T89454-", - "T89455-", - "A89456-", - "C89457-", - "A89458-", - "A89459-", - "A89460-", - "C89461-", - "A89462-", - "A89463-", - "C89464-", - "A89466-", - "G89467-", - "G89468-", - "A89469-", - "A89470-", - "A89471-", - "T89472-", - "T89473-", - "G89474-", - "G89475-", - "T89476-", - "T89477-", - "T89478-", - "A89479-", - "T89480-", - "G89481-", - "A89482-", - "T89483-", - "G89484-", - "T89485-", - "A89486-", - "T89487-", - "A89488-", - "A89489-", - "T89490-", - "T89491-", - "T89492-", - "T89493-", - "T89494-", - "T89495-", - "T89496-", - "A89497-", - "G89498-", - "T89499-", - "T89500-", - "T89503-", - "A89504-", - "T89505-", - "A89506-", - "G89507-", - "A89508-", - "T89509-", - "T89510-", - "C89511-", - "T89512-", - "T89513-", - "T89514-", - "A89515-", - "T89516-", - "T89517-", - "C89518-", - "T89519-", - "A89520-", - "T89521-", - "A89522-", - "C89523-", - "T89524-", - "T89525-", - "A89526-", - "A89527-", - "A89528-", - "A89529-", - "A89530-", - "A89531-", - "T89532-", - "G89533-", - "A89534-", - "A89535-", - "A89536-", - "A89537-", - "T89538-", - "A89539-", - "A89540-", - "A89541-", - "T89542-", - "A89543-", - "C89544-", - "A89545-", - "A89546-", - "A89547-", - "G89548-", - "G89549-", - "T89550-", - "T89551-", - "C89552-", - "T89553-", - "T89554-", - "A89556-", - "G89557-", - "G89558-", - "G89559-", - "T89560-", - "T89561-", - "G89562-", - "T89563-", - "G89564-", - "T89565-", - "T89566-", - "A89567-", - "A89568-", - "T89569-", - "T89570-", - "G89571-", - "A89572-", - "A89573-", - "A89574-", - "G89575-", - "C89576-", - "G89577-", - "A89578-", - "T89579-", - "A89580-", - "A89581-", - "A89582-", - "T89583-", - "A89584-", - "A89585-", - "T89586-", - "C89587-", - "A89588-", - "T89589-", - "A89590-", - "A89591-", - "A89592-", - "T89593-", - "T89594-", - "A89595-", - "T89596-", - "T89597-", - "T89598-", - "C89599-", - "A89600-", - "T89601-", - "T89602-", - "A89603-", - "T89604-", - "C89605-", - "G89606-", - "C89607-", - "G89608-", - "A89609-", - "T89610-", - "A89611-", - "T89612-", - "C89613-", - "C89614-", - "G89615-", - "T89616-", - "T89617-", - "A89619-", - "G89620-", - "T89621-", - "T89622-", - "T89623-", - "G89624-", - "A89626-", - "T89627-", - "C89628-", - "G89629-", - "T89630-", - "A89631-", - "A89632-", - "T89633-", - "G89634-", - "G89635-", - "C89636-", - "G89637-", - "T89638-", - "G89639-", - "G89640-", - "T89641-", - "C89642-", - "A89643-", - "A89644-", - "T89645-", - "T89646-", - "A89647-", - "C89648-", - "G89649-", - "A89650-", - "A89651-", - "T89652-", - "A89653-", - "A89654-", - "A89655-", - "G89656-", - "C89657-", - "G89658-", - "G89659-", - "A89662-", - "A89665-", - "G89666-", - "T89667-", - "A89668-", - "G89669-", - "T89670-", - "T89672-", - "C89673-", - "A89677-", - "A89678-", - "A89680-", - "T89681-", - "G89682-", - "T89685-", - "G89686-", - "A89687-", - "A89688-", - "A89689-", - "T89690-", - "C89691-", - "A89692-", - "G89693-", - "A89694-", - "G89695-", - "C89696-", - "T89697-", - "C89698-", - "A89699-", - "C89701-", - "T89702-", - "A89707-", - "A89708-", - "T89709-", - "A89710-", - "G89711-", - "C89712-", - "G89713-", - "C89714-", - "T89715-", - "G89716-", - "A89717-", - "A89718-", - "A89719-", - "A89720-", - "T89721-", - "A89722-", - "A89723-", - "A89724-", - "G89725-", - "A89726-", - "T89727-", - "A89728-", - "A89729-", - "A89730-", - "A89732-", - "C89733-", - "G89734-", - "A89735-", - "G89736-", - "G89737-", - "A89738-", - "T89739-", - "A89740-", - "T89741-", - "T89742-", - "T89743-", - "T89744-", - "C89745-", - "C89746-", - "C89747-", - "G89748-", - "G89749-", - "A89750-", - "A89751-", - "G89752-", - "A89753-", - "T89754-", - "G89755-", - "T89756-", - "A89757-", - "A89758-", - "T89759-", - "A89760-", - "A89761-", - "T89762-", - "T89763-", - "C89764-", - "C89765-", - "A89766-", - "T89767-", - "C89768-", - "T89769-", - "A89770-", - "C89771-", - "T89772-", - "A89773-", - "A89774-", - "G89775-", - "C89776-", - "C89777-", - "C89778-", - "A89779-", - "A89780-", - "A89781-", - "A89782-", - "C89783-", - "C89784-", - "A89785-", - "A89786-", - "A89787-", - "C89788-", - "G89789-", - "A89790-", - "A89791-", - "C89792-", - "C89793-", - "A89794-", - "C89795-", - "T89796-", - "A89797-", - "C89798-", - "T89799-", - "C89800-", - "C89803-", - "G89804-", - "T89805-", - "A89806-", - "A89807-", - "A89808-", - "C89809-", - "C89810-", - "A89811-", - "G89812-", - "C89813-", - "G89814-", - "G89815-", - "C89816-", - "T89817-", - "A89818-", - "C89819-", - "T89820-", - "A89821-", - "A89822-", - "A89823-", - "A89824-", - "G89825-", - "A89826-", - "T89827-", - "C89828-", - "A89829-", - "A89830-", - "C89831-", - "C89832-", - "A89833-", - "A89834-", - "A89835-", - "A89836-", - "A89837-", - "G89838-", - "G89839-", - "A89840-", - "T89841-", - "A89842-", - "A89843-", - "A89844-", - "G89845-", - "A89846-", - "A89847-", - "A89848-", - "A89849-", - "G89850-", - "G89851-", - "A89852-", - "G89853-", - "G89854-", - "A89855-", - "A89856-", - "G89857-", - "T89858-", - "G89859-", - "G89860-", - "A89861-", - "A89862-", - "G89863-", - "A89864-", - "A89865-", - "G89866-", - "T89867-", - "A89868-", - "G89869-", - "T89870-", - "T89871-", - "A89872-", - "T89873-", - "A89876-", - "G89877-", - "G89878-", - "A89879-", - "A89880-", - "T89881-", - "A89882-", - "T89883-", - "C89884-", - "A89885-", - "T89886-", - "C89887-", - "A89888-", - "A89889-", - "A89890-", - "C89891-", - "A89892-", - "A89893-", - "C89894-", - "T89895-", - "G89896-", - "A89897-", - "A89898-", - "G89899-", - "A89900-", - "A89901-", - "A89902-", - "A89903-", - "T89904-", - "T89905-", - "C89906-", - "T89907-", - "C89908-", - "C89909-", - "A89910-", - "C89911-", - "C89912-", - "T89913-", - "C89914-", - "C89915-", - "G89916-", - "T89917-", - "C89918-", - "A89919-", - "T89920-", - "C89921-", - "A89922-", - "T89923-", - "C89924-", - "T89925-", - "C89926-", - "C89927-", - "T89928-", - "G89929-", - "G89930-", - "A89931-", - "G89932-", - "T89933-", - "C89934-", - "G89935-", - "G89936-", - "C89937-", - "G89938-", - "A89939-", - "C89940-", - "A89941-", - "T89942-", - "T89943-", - "G89944-", - "T89945-", - "A89946-", - "G89947-", - "A89948-", - "A89949-", - "A89950-", - "G89951-", - "C89952-", - "G89953-", - "T89954-", - "G89955-", - "G89956-", - "C89957-", - "C89958-", - "G89959-", - "C89960-", - "T89961-", - "G89962-", - "T89963-", - "A89964-", - "G89965-", - "T89969-", - "C89970-", - "G89971-", - "A89972-", - "T89973-", - "G89974-", - "A89975-", - "T89976-", - "A89977-", - "G89978-", - "C89979-", - "G89980-", - "A89981-", - "C89982-", - "G89983-", - "G89984-", - "G89985-", - "G89986-", - "A89987-", - "T89988-", - "G89989-", - "A89990-", - "T89991-", - "G89992-", - "A89993-", - "A89994-", - "C89995-", - "C89996-", - "T89997-", - "A89998-", - "T89999-", - "G90000-", - "G90001-", - "T90002-", - "A90003-", - "C90004-", - "A90005-", - "A90006-", - "G90007-", - "T90008-", - "T90009-", - "G90010-", - "A90011-", - "A90012-", - "G90013-", - "C90014-", - "T90015-", - "G90016-", - "G90017-", - "T90018-", - "A90019-", - "A90020-", - "A90021-", - "G90022-", - "T90023-", - "A90024-", - "A90025-", - "A90026-", - "T90027-", - "C90028-", - "A90029-", - "T90030-", - "A90031-", - "G90032-", - "T90033-", - "G90034-", - "C90035-", - "T90036-", - "A90037-", - "G90038-", - "C90042-", - "G90043-", - "A90044-", - "T90045-", - "T90047-", - "C90048-", - "T90049-", - "C90050-", - "G90052-", - "A90053-", - "C90054-", - "C90055-", - "T90056-", - "A90057-", - "A90058-", - "A90059-", - "G90060-", - "G90061-", - "T90062-", - "G90063-", - "G90064-", - "C90065-", - "T90066-", - "A90067-", - "C90068-", - "C90069-", - "G90070-", - "A90071-", - "C90072-", - "A90073-", - "A90074-", - "T90075-", - "A90076-", - "T90077-", - "C90078-", - "G90079-", - "T90080-", - "T90081-", - "A90082-", - "A90083-", - "A90084-", - "G90085-", - "A90086-", - "T90087-", - "C90088-", - "T90089-", - "T90090-", - "A90091-", - "A90092-", - "G90093-", - "A90094-", - "A90095-", - "A90096-", - "A90097-", - "T90098-", - "T90099-", - "A90100-", - "T90101-", - "T90105-", - "A90106-", - "G90107-", - "A90108-", - "A90109-", - "T90110-", - "C90111-", - "T90112-", - "C90113-", - "T90114-", - "G90115-", - "C90116-", - "A90117-", - "G90118-", - "T90119-", - "A90120-", - "T90121-", - "C90122-", - "G90123-", - "A90124-", - "C90125-", - "T90126-", - "G90127-", - "T90128-", - "T90129-", - "C90130-", - "T90131-", - "A90132-", - "G90133-", - "A90134-", - "G90135-", - "G90136-", - "A90137-", - "T90138-", - "G90139-", - "T90140-", - "T90141-", - "C90142-", - "A90143-", - "A90144-", - "G90145-", - "C90146-", - "A90147-", - "G90148-", - "C90149-", - "T90150-", - "G90151-", - "G90152-", - "A90154-", - "T90155-", - "C90156-", - "T90157-", - "C90158-", - "T90159-", - "A90162-", - "A90164-", - "A90165-", - "T90166-", - "T90167-", - "T90168-", - "A90169-", - "C90170-", - "T90171-", - "T90172-", - "T90174-", - "A90175-", - "T90176-", - "T90180-", - "A90181-", - "A90182-", - "G90184-", - "C90185-", - "T90188-", - "T90189-", - "A90190-", - "C90191-", - "A90192-", - "A90193-", - "C90194-", - "A90195-", - "C90196-", - "T90197-", - "A90198-", - "T90199-", - "C90200-", - "T90201-", - "G90202-", - "A90203-", - "C90205-", - "T90206-", - "A90207-", - "G90208-", - "T90209-", - "C90210-", - "A90211-", - "C90212-", - "A90215-", - "G90216-", - "G90217-", - "G90218-", - "A90219-", - "A90220-", - "A90221-", - "A90222-", - "T90223-", - "C90224-", - "T90225-", - "A90226-", - "A90227-", - "A90228-", - "G90229-", - "T90230-", - "T90231-", - "T90234-", - "C90235-", - "G90236-", - "T90237-", - "A90238-", - "A90239-", - "A90240-", - "A90241-", - "A90242-", - "A90243-", - "G90244-", - "T90245-", - "T90246-", - "A90247-", - "A90248-", - "A90249-", - "A90250-", - "C90251-", - "T90252-", - "T90253-", - "G90254-", - "T90255-", - "A90256-", - "A90257-", - "G90258-", - "A90259-", - "A90260-", - "G90261-", - "T90262-", - "A90263-", - "A90264-", - "A90265-", - "T90266-", - "G90267-", - "C90268-", - "G90269-", - "T90270-", - "G90271-", - "C90272-", - "A90273-", - "C90274-", - "T90275-", - "T90276-", - "T90277-", - "T90278-", - "T90279-", - "T90280-", - "A90281-", - "T90282-", - "A90283-", - "A90284-", - "A90285-", - "G90286-", - "A90287-", - "T90288-", - "G90289-", - "G90290-", - "T90291-", - "A90292-", - "A90293-", - "A90294-", - "C90295-", - "T90296-", - "G90297-", - "T90298-", - "T90299-", - "T90300-", - "A90301-", - "C90302-", - "C90303-", - "G90304-", - "A90305-", - "T90306-", - "A90307-", - "A90308-", - "T90309-", - "A90310-", - "A90311-", - "T90312-", - "T90313-", - "T90314-", - "T90315-", - "T90316-", - "T90317-", - "A90318-", - "A90319-", - "A90320-", - "T90321-", - "C90322-", - "C90323-", - "T90324-", - "G90325-", - "T90326-", - "A90327-", - "T90328-", - "C90329-", - "A90330-", - "A90332-", - "G90334-", - "A90335-", - "T90336-", - "A90337-", - "A90338-", - "T90339-", - "C90340-", - "C90341-", - "A90342-", - "G90343-", - "C90344-", - "G90345-", - "T90346-", - "A90347-", - "T90348-", - "G90349-", - "A90350-", - "G90351-", - "G90352-", - "T90353-", - "T90354-", - "T90355-", - "T90356-", - "G90357-", - "C90358-", - "A90359-", - "A90360-", - "C90361-", - "A90362-", - "T90363-", - "G90364-", - "T90365-", - "T90366-", - "A90367-", - "A90368-", - "A90369-", - "A90370-", - "T90371-", - "T90372-", - "C90373-", - "C90374-", - "T90375-", - "A90376-", - "C90377-", - "T90378-", - "C90379-", - "A90380-", - "T90381-", - "T90382-", - "T90383-", - "A90384-", - "A90385-", - "C90386-", - "A90387-", - "G90388-", - "A90389-", - "T90390-", - "G90391-", - "T90392-", - "A90393-", - "G90394-", - "T90395-", - "A90396-", - "G90397-", - "T90398-", - "A90399-", - "T90400-", - "A90401-", - "T90402-", - "G90403-", - "A90404-", - "A90405-", - "C90406-", - "A90407-", - "A90408-", - "A90409-", - "C90410-", - "G90411-", - "T90412-", - "G90413-", - "G90414-", - "G90415-", - "A90416-", - "A90417-", - "G90418-", - "A90419-", - "G90420-", - "G90421-", - "C90422-", - "A90423-", - "T90424-", - "T90425-", - "A90426-", - "A90427-", - "C90428-", - "T90429-", - "A90430-", - "G90431-", - "A90432-", - "T90433-", - "T90434-", - "A90435-", - "A90436-", - "T90437-", - "T90438-", - "T90439-", - "T90440-", - "T90441-", - "G90442-", - "T90443-", - "G90444-", - "G90445-", - "G90446-", - "A90447-", - "A90448-", - "G90449-", - "T90450-", - "G90451-", - "A90452-", - "T90453-", - "T90454-", - "C90455-", - "A90456-", - "A90457-", - "A90458-", - "A90459-", - "G90460-", - "G90461-", - "A90462-", - "C90463-", - "G90464-", - "T90465-", - "A90466-", - "G90467-", - "A90468-", - "C90469-", - "A90470-", - "A90471-", - "T90472-", - "A90473-", - "C90474-", - "T90475-", - "T90476-", - "T90477-", - "T90478-", - "A90479-", - "C90480-", - "G90481-", - "G90482-", - "A90483-", - "A90484-", - "A90485-", - "A90486-", - "A90487-", - "T90488-", - "G90489-", - "C90490-", - "A90491-", - "T90492-", - "A90493-", - "T90494-", - "A90495-", - "C90496-", - "A90497-", - "G90498-", - "A90499-", - "A90500-", - "T90501-", - "C90502-", - "G90503-", - "C90504-", - "A90505-", - "A90506-", - "T90507-", - "G90508-", - "C90509-", - "T90510-", - "A90511-", - "A90512-", - "A90513-", - "A90514-", - "G90515-", - "A90516-", - "G90517-", - "A90518-", - "T90519-", - "C90520-", - "G90521-", - "T90522-", - "A90523-", - "T90524-", - "T90525-", - "T90526-", - "T90527-", - "T90528-", - "G90529-", - "T90530-", - "T90531-", - "A90532-", - "G90533-", - "A90534-", - "G90535-", - "T90536-", - "A90537-", - "T90538-", - "A90539-", - "T90540-", - "A90541-", - "A90542-", - "C90543-", - "G90544-", - "T90545-", - "T90546-", - "A90547-", - "T90548-", - "G90549-", - "A90550-", - "A90551-", - "A90552-", - "C90553-", - "G90554-", - "A90555-", - "A90556-", - "T90557-", - "T90558-", - "A90559-", - "A90560-", - "T90561-", - "T90562-", - "G90563-", - "T90564-", - "T90565-", - "T90566-", - "T90567-", - "A90568-", - "T90569-", - "A90570-", - "A90571-", - "A90572-", - "C90573-", - "A90574-", - "A90575-", - "A90576-", - "A90577-", - "A90578-", - "T90579-", - "A90580-", - "T90581-", - "A90582-", - "A90583-", - "A90584-", - "G90585-", - "A90586-", - "A90587-", - "A90588-", - "T90589-", - "C90590-", - "G90591-", - "G172114-", - "T172115-", - "G172116-", - "C172117-", - "A172140-", - "A172141-", - "T172142-", - "T172143-", - "G172144-", - "A194548-" - ], - "OPG002": [ - "G30X", - "*350X" - ], - "OPG080": [ - "T69-", - "Q70-", - "H71-", - "P72-", - "D73-", - "Y74-", - "X75-", - "X77-", - "S84-", - "N85-", - "L86X", - "L93-", - "F94X", - "N103X", - "Y104-", - "V105-", - "N106-", - "P107-", - "K108-", - "N109-", - "G110-", - "K111-", - "H112-", - "S113-", - "X114-", - "I115-", - "K130X", - "L131-", - "N132X" - ], - "OPG082": [ - "X360-", - "X361-", - "X364-", - "X366-" - ], - "OPG109": [ - "M1-", - "D2-", - "S3-", - "K4-", - "E5-", - "X6-", - "X7-", - "L8-", - "I9-", - "X10-", - "I11-", - "K14-", - "X15-", - "X16-", - "X18-", - "P26-", - "K27-", - "S28-", - "Y29-", - "N30-", - "D31-", - "F32-", - "I33-", - "S34-", - "R35-", - "N36-", - "K37-", - "N38-", - "I39-", - "X41-", - "I42-", - "N43-", - "L44-", - "Y45-", - "N46-", - "V47-", - "S48-", - "T49-", - "I50-", - "T51-", - "E52-", - "X53-", - "X54-", - "I55-", - "R56-", - "L57-", - "L58-", - "Y59-", - "T60-", - "T61-", - "I62-", - "E63-", - "Q64-", - "N65-", - "I66-", - "D67-", - "A68-", - "D69-", - "D70-", - "X71-", - "X73-", - "X74-", - "X77-", - "X78-", - "Y79-", - "I80-", - "G81-", - "Y82-", - "K83-", - "F84-", - "E85-", - "Q86-", - "T87-", - "X88-", - "X90-", - "E91-", - "I92-", - "X93-", - "X94-", - "S95-", - "L96-", - "S97-", - "X98-", - "X99-", - "N102-", - "T103-", - "T104-", - "D105-", - "E106-", - "M107-", - "T108-", - "Y109-", - "N110-", - "L111-", - "Y112-", - "D113-", - "L114-", - "F115-", - "N117-", - "T118-", - "L119-", - "D120-", - "M121-", - "Y122-", - "L123-", - "R124-", - "Q125-", - "K126-", - "K127-", - "I128-", - "S129-", - "I130-", - "L131-", - "V132-", - "N133-", - "D134-", - "D135-", - "V136-", - "R137-", - "G138-", - "D139-", - "V140-", - "I141-", - "V142-", - "S143-", - "Y144-", - "K145-", - "N146-", - "S147-", - "D148-", - "L149-", - "V150-", - "S151-", - "S152-", - "F153-", - "N154-", - "A155-", - "E156-", - "L157-", - "E158-", - "P159-", - "E160-", - "I161-", - "K162-", - "K163-", - "I164-", - "P165-", - "F166-", - "N167-", - "M168-", - "K169-", - "N170-", - "L171-", - "L172-", - "P173-", - "Y174-", - "L175-", - "E176-", - "K177-", - "N178-", - "L179-", - "D180-", - "Q181-", - "L182-", - "R183-", - "F184-", - "S185-", - "K186-", - "K187-", - "Y188-", - "L189-", - "D190-", - "F191-", - "A192-", - "Y193-", - "L194-", - "C195-", - "R196-", - "H197-", - "I198-", - "G199-", - "I200-", - "P201-", - "I202-", - "S203-", - "K204-", - "K205-", - "K206-", - "Y207-", - "N208-", - "M209-", - "R210-", - "Y211-", - "V212-", - "F213-", - "L214-", - "Y215-", - "K216-", - "I217-", - "D218-", - "G219-", - "L220-", - "S221-", - "I222-", - "P223-", - "I224-", - "I225-", - "I226-", - "K227-", - "D228-", - "F229-", - "L230-", - "D231-", - "I232-", - "K233-", - "Y234-", - "V235-", - "Y236-", - "L237-", - "E238-", - "N239-", - "T240-", - "G241-", - "K242-", - "I243-", - "Y244-", - "K245-", - "N246-", - "S247-", - "F248-", - "S249-", - "E250-", - "D251-", - "H252-", - "N253-", - "N254-", - "S255-", - "L256-", - "S257-", - "D258-", - "W259-", - "G260-", - "K261-", - "V262-", - "I263-", - "I264-", - "P265-", - "L266-", - "L267-", - "K268-", - "D269-", - "R270-", - "H271-", - "L272-", - "Y273-", - "S274-", - "Y275-", - "I276-", - "F277-", - "L278-", - "S279-", - "S280-", - "Y281-", - "H282-", - "L283-", - "H284-", - "S285-", - "Y286-", - "Y287-", - "T288-", - "D289-", - "L290-", - "I291-", - "A292-", - "R293-", - "D294-", - "E295-", - "P296-", - "V297-", - "F298-", - "V299-", - "K300-", - "R301-", - "K302-", - "K303-", - "L304-", - "D305-", - "I306-", - "I307-", - "E308-", - "I309-", - "X796*" - ], - "OPG110": [ - "M1-", - "A2-", - "W3-", - "S4-", - "I5-", - "T6-", - "N7-", - "K8-", - "A9-", - "X10-", - "X11-", - "S12-", - "S13-", - "X14-", - "X16-", - "M17-", - "X18-", - "E19-", - "I20-", - "R21-", - "A22-", - "X23-", - "X24-", - "N26-", - "S27-", - "A28-", - "E29-", - "N30-", - "K31-", - "D32-", - "K33-", - "X34-", - "E35-", - "D36-", - "I37-", - "F38-", - "P39-", - "E40-", - "D41-", - "V42-", - "I43-", - "I44-", - "P45-", - "S46-", - "T47-", - "K48-", - "P49-", - "K50-", - "T51-", - "K52-", - "R53-", - "T54-", - "T55-", - "T56-", - "X57-", - "R58-", - "K59-", - "P60-", - "A61-", - "A62-", - "T63-", - "K64-", - "R65-", - "S66-", - "T67-", - "K68-", - "K69-", - "D70-", - "K71-", - "E72-", - "K73-", - "E74-", - "E75-", - "V76-", - "E77-", - "E78-", - "V79-", - "V80-", - "X81-", - "X82-", - "E83-", - "Y84-", - "H85-", - "Q86-", - "T87-", - "T88-", - "E89-", - "E90-", - "N91-", - "S92-", - "P93-", - "P94-", - "P95-", - "S96-", - "S97-", - "S98-", - "P99-", - "G100-", - "V101-", - "G102-", - "D103-", - "I104-", - "V105-", - "E106-", - "S107-", - "V108-", - "A109-", - "A110-", - "V111-", - "X112-", - "X113-", - "D114-", - "D115-", - "S116-", - "D117-", - "G118-", - "D119-", - "D120-", - "E121-", - "P122-", - "M123-", - "V124-", - "Q125-", - "V126-", - "E127-", - "A128-", - "G129-", - "K130-", - "V131-", - "N132-", - "H133-", - "S134-", - "A135-", - "X136-", - "X137-", - "D138-", - "X139-", - "X140-", - "D141-", - "L142-", - "K143-", - "V144-", - "A145-", - "T146-", - "D147-", - "N148-", - "I149-", - "V150-", - "K151-", - "D152-", - "L153-", - "K154-", - "K155-", - "I156-", - "X157-", - "X158-", - "R159-", - "I160-", - "S161-", - "A162-", - "V163-", - "S164-", - "T165-", - "V166-", - "L167-", - "E168-", - "D169-", - "V170-", - "Q171-", - "A172-", - "A173-", - "X174-", - "I175-", - "S176-", - "X177-", - "X178-", - "F179-", - "T180-", - "X181-", - "X182-", - "X183-", - "X184-", - "X185-", - "X186-", - "T187-", - "T188-", - "L189-", - "S190-", - "X191-", - "L192-", - "V193-", - "X194-", - "X195-", - "G196-", - "K197-", - "S198-", - "K199-", - "V200-", - "X201-", - "R202-", - "K203-", - "K204-", - "V205-", - "K206-", - "T207-", - "C208-", - "K209-", - "K210-", - "X211-" - ], - "OPG111": [ - "M1-", - "R2-", - "A3-", - "L4-", - "F5-", - "Y6-", - "K7-", - "D8-", - "G9-", - "K10-", - "L11-", - "F12-", - "T13-", - "D14-", - "N15-", - "N16-", - "F17-", - "L18-", - "N19-", - "P20-", - "V21-", - "S22-", - "X23-", - "D24-", - "N25-", - "P26-", - "A27-", - "Y28-", - "E29-", - "V30-", - "L31-", - "Q32-", - "H33-", - "V34-", - "K35-", - "I36-", - "P37-", - "T38-", - "H39-", - "L40-", - "T41-", - "D42-", - "V43-", - "V44-", - "V45-", - "Y46-", - "E47-", - "Q48-", - "T49-", - "W50-", - "E51-", - "E52-", - "A53-", - "L54-", - "T55-", - "R56-", - "L57-", - "I58-", - "F59-", - "V60-", - "G61-", - "S62-", - "D63-", - "S64-", - "K65-", - "G66-", - "R67-", - "R68-", - "Q69-", - "Y70-", - "F71-", - "Y72-", - "G73-", - "K74-", - "M75-", - "H76-", - "I77-", - "Q78-", - "N79-", - "R80-", - "N81-", - "A82-", - "K83-", - "R84-", - "D85-", - "R86-", - "I87-", - "F88-", - "V89-", - "R90-", - "V91-", - "Y92-", - "N93-", - "V94-", - "M95-", - "K96-", - "R97-", - "I98-", - "N99-", - "C100-", - "F101-", - "I102-", - "N103-", - "K104-", - "N105-", - "I106-", - "K107-", - "K108-", - "S109-", - "X315*" - ] - }, - "labels": { - "aa": "OPG002: G30X, *350X; OPG080: T69-, Q70-, H71-, P72-, D73-, Y74-, X75-, X77-, S84-, N85-, L86X, L93-, F94X, N103X, Y104-, V105-, N106-, P107-, K108-, N109-, G110-, K111-, H112-, S113-, X114-, I115-, K130X, L131-, N132X; OPG082: X360-, X361-, X364-, X366-; OPG109: M1-, D2-, S3-, K4-, E5-, X6-, X7-, L8-, I9-, X10-, I11-, K14-, X15-, X16-, X18-, P26-, K27-, S28-, Y29-, N30-, D31-, F32-, I33-, S34-, R35-, N36-, K37-, N38-, I39-, X41-, I42-, N43-, L44-, Y45-, N46-, V47-, S48-, T49-, I50-, T51-, E52-, X53-, X54-, I55-, R56-, L57-, L58-, Y59-, T60-, T61-, I62-, E63-, Q64-, N65-, I66-, D67-, A68-, D69-, D70-, X71-, X73-, X74-, X77-, X78-, Y79-, I80-, G81-, Y82-, K83-, F84-, E85-, Q86-, T87-, X88-, X90-, E91-, I92-, X93-, X94-, S95-, L96-, S97-, X98-, X99-, N102-, T103-, T104-, D105-, E106-, M107-, T108-, Y109-, N110-, L111-, Y112-, D113-, L114-, F115-, N117-, T118-, L119-, D120-, M121-, Y122-, L123-, R124-, Q125-, K126-, K127-, I128-, S129-, I130-, L131-, V132-, N133-, D134-, D135-, V136-, R137-, G138-, D139-, V140-, I141-, V142-, S143-, Y144-, K145-, N146-, S147-, D148-, L149-, V150-, S151-, S152-, F153-, N154-, A155-, E156-, L157-, E158-, P159-, E160-, I161-, K162-, K163-, I164-, P165-, F166-, N167-, M168-, K169-, N170-, L171-, L172-, P173-, Y174-, L175-, E176-, K177-, N178-, L179-, D180-, Q181-, L182-, R183-, F184-, S185-, K186-, K187-, Y188-, L189-, D190-, F191-, A192-, Y193-, L194-, C195-, R196-, H197-, I198-, G199-, I200-, P201-, I202-, S203-, K204-, K205-, K206-, Y207-, N208-, M209-, R210-, Y211-, V212-, F213-, L214-, Y215-, K216-, I217-, D218-, G219-, L220-, S221-, I222-, P223-, I224-, I225-, I226-, K227-, D228-, F229-, L230-, D231-, I232-, K233-, Y234-, V235-, Y236-, L237-, E238-, N239-, T240-, G241-, K242-, I243-, Y244-, K245-, N246-, S247-, F248-, S249-, E250-, D251-, H252-, N253-, N254-, S255-, L256-, S257-, D258-, W259-, G260-, K261-, V262-, I263-, I264-, P265-, L266-, L267-, K268-, D269-, R270-, H271-, L272-, Y273-, S274-, Y275-, I276-, F277-, L278-, S279-, S280-, Y281-, H282-, L283-, H284-, S285-, Y286-, Y287-, T288-, D289-, L290-, I291-, A292-, R293-, D294-, E295-, P296-, V297-, F298-, V299-, K300-, R301-, K302-, K303-, L304-, D305-, I306-, I307-, E308-, I309-, X796*; OPG110: M1-, A2-, W3-, S4-, I5-, T6-, N7-, K8-, A9-, X10-, X11-, S12-, S13-, X14-, X16-, M17-, X18-, E19-, I20-, R21-, A22-, X23-, X24-, N26-, S27-, A28-, E29-, N30-, K31-, D32-, K33-, X34-, E35-, D36-, I37-, F38-, P39-, E40-, D41-, V42-, I43-, I44-, P45-, S46-, T47-, K48-, P49-, K50-, T51-, K52-, R53-, T54-, T55-, T56-, X57-, R58-, K59-, P60-, A61-, A62-, T63-, K64-, R65-, S66-, T67-, K68-, K69-, D70-, K71-, E72-, K73-, E74-, E75-, V76-, E77-, E78-, V79-, V80-, X81-, X82-, E83-, Y84-, H85-, Q86-, T87-, T88-, E89-, E90-, N91-, S92-, P93-, P94-, P95-, S96-, S97-, S98-, P99-, G100-, V101-, G102-, D103-, I104-, V105-, E106-, S107-, V108-, A109-, A110-, V111-, X112-, X113-, D114-, D115-, S116-, D117-, G118-, D119-, D120-, E121-, P122-, M123-, V124-, Q125-, V126-, E127-, A128-, G129-, K130-, V131-, N132-, H133-, S134-, A135-, X136-, X137-, D138-, X139-, X140-, D141-, L142-, K143-, V144-, A145-, T146-, D147-, N148-, I149-, V150-, K151-, D152-, L153-, K154-, K155-, I156-, X157-, X158-, R159-, I160-, S161-, A162-, V163-, S164-, T165-, V166-, L167-, E168-, D169-, V170-, Q171-, A172-, A173-, X174-, I175-, S176-, X177-, X178-, F179-, T180-, X181-, X182-, X183-, X184-, X185-, X186-, T187-, T188-, L189-, S190-, X191-, L192-, V193-, X194-, X195-, G196-, K197-, S198-, K199-, V200-, X201-, R202-, K203-, K204-, V205-, K206-, T207-, C208-, K209-, K210-, X211-; OPG111: M1-, R2-, A3-, L4-, F5-, Y6-, K7-, D8-, G9-, K10-, L11-, F12-, T13-, D14-, N15-, N16-, F17-, L18-, N19-, P20-, V21-, S22-, X23-, D24-, N25-, P26-, A27-, Y28-, E29-, V30-, L31-, Q32-, H33-, V34-, K35-, I36-, P37-, T38-, H39-, L40-, T41-, D42-, V43-, V44-, V45-, Y46-, E47-, Q48-, T49-, W50-, E51-, E52-, A53-, L54-, T55-, R56-, L57-, I58-, F59-, V60-, G61-, S62-, D63-, S64-, K65-, G66-, R67-, R68-, Q69-, Y70-, F71-, Y72-, G73-, K74-, M75-, H76-, I77-, Q78-, N79-, R80-, N81-, A82-, K83-, R84-, D85-, R86-, I87-, F88-, V89-, R90-, V91-, Y92-, N93-, V94-, M95-, K96-, R97-, I98-, N99-, C100-, F101-, I102-, N103-, K104-, N105-, I106-, K107-, K108-, S109-, X315*" - } - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000041", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C9389T", - "G161797A", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A185557C" - ], - "OPG188": [ - "E68K" - ], - "OPG210": [ - "K1401T" - ] - }, - "labels": { - "aa": "OPG188: E68K; OPG210: K1401T", - "clade": "B.1.16" - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-24561-E", - "node_attrs": { - "div": 4, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-24561-E" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP642395" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-07" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G161421A" - ], - "OPG187": [ - "R267K" - ] - }, - "labels": { - "aa": "OPG187: R267K" - } - } - }, - { - "name": "NODE_0000042", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C30154T" - ] - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-23596-O", - "node_attrs": { - "div": 5, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-23596-O" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP459211" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-29" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G170076A" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-24909-C", - "node_attrs": { - "div": 6, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-24909-C" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP642383" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-09" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6863A", - "C132608T" - ] - } - } - }, - { - "name": "DC_INS_MPX_0082_L", - "node_attrs": { - "div": 4, - "author": { - "author": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M.", - "value": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M." - }, - "strain_original": { - "value": "DC_INS_MPX_0082_L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP693647" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-08" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A356-", - "C357-", - "A358-", - "T195509-", - "A195510-", - "A195511-" - ] - } - } - }, - { - "name": "DC_INS_MPX_0719_L", - "node_attrs": { - "div": 5, - "author": { - "author": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M.", - "value": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M." - }, - "strain_original": { - "value": "DC_INS_MPX_0719_L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP693653" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-29" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G121275A" - ], - "OPG139": [ - "P32S" - ] - }, - "labels": { - "aa": "OPG139: P32S" - } - } - }, - { - "name": "NODE_0000043", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G23673A", - "G37974A", - "-178536T", - "-178537A", - "-178538T", - "-178539A", - "-178540A", - "-178541G", - "-178542C", - "-178543G", - "-178544G", - "-178545T", - "-178546C", - "-178547G", - "-178548T", - "-178549A", - "-178550C", - "-178551C", - "-178552C", - "-178553A" - ], - "OPG039": [ - "S149L" - ], - "OPG056": [ - "S354L" - ] - }, - "labels": { - "aa": "OPG039: S149L; OPG056: S354L" - } - }, - "children": [ - { - "name": "SAN_INS_MPX_0971_L", - "node_attrs": { - "div": 6, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "strain_original": { - "value": "SAN_INS_MPX_0971_L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP819959" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-11" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "ANT-LDSP-ANT-MPX-30512O", - "node_attrs": { - "div": 6, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-30512O" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ696097" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-10" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-" - ] - } - } - } - ] - }, - { - "name": "NODE_0000044", - "node_attrs": { - "div": 5, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G148403A", - "-178536T", - "-178537A", - "-178538T", - "-178539A", - "-178540A", - "-178541G", - "-178542C", - "-178543G", - "-178544G", - "-178545T", - "-178546C", - "-178547G", - "-178548T", - "-178549A", - "-178550C", - "-178551C", - "-178552C", - "-178553A" - ] - } - }, - "children": [ - { - "name": "VAC_INS_MPX_1050_C", - "node_attrs": { - "div": 7, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "strain_original": { - "value": "VAC_INS_MPX_1050_C" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP837481" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-26" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G69840A", - "G161421A", - "A196376-", - "T196377-", - "C196378-" - ], - "OPG187": [ - "R267K" - ] - }, - "labels": { - "aa": "OPG187: R267K" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-30094O", - "node_attrs": { - "div": 7, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-30094O" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ696095" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-08" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T548-", - "A549-", - "A550-", - "G104597A", - "C116175T", - "G150585A", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-" - ] - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000045", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A11326-", - "T11327-", - "C11328-", - "T11329-", - "A11330-", - "C11331-", - "G11332-", - "A11333-", - "T11334-", - "A11335-", - "T11336-", - "T11337-", - "A11338-", - "G11339-", - "A11340-", - "T11341-", - "A11342-", - "C11343-", - "T11344-", - "T11345-", - "C11346-", - "A11347-", - "C11348-", - "T11349-", - "C11350-", - "A11351-", - "A11352-", - "T11353-", - "G11354-", - "A11355-", - "A11356-", - "T11357-", - "C11358-", - "A11359-", - "A11360-", - "T11361-", - "C11362-", - "A11363-", - "C11364-", - "A11365-", - "C11366-", - "A11367-", - "A11368-", - "T11369-", - "C11370-", - "T11371-", - "A11372-", - "A11373-", - "T11374-", - "G11375-", - "T11376-", - "A11377-", - "G11378-", - "G11379-", - "T11380-", - "T11381-", - "T11382-", - "A11383-", - "T11384-", - "G11385-", - "A11386-", - "C11387-", - "A11388-", - "T11389-", - "A11390-", - "A11391-", - "T11392-", - "A11393-", - "G11394-", - "C11395-", - "A11396-", - "T11397-", - "T11398-", - "T11399-", - "T11400-", - "C11401-", - "A11402-", - "G11403-", - "C11404-", - "A11405-", - "G11406-", - "T11407-", - "T11408-", - "C11409-", - "A11410-", - "A11411-", - "T11412-", - "G11413-", - "T11414-", - "T11415-", - "T11416-", - "C11417-", - "T11418-", - "A11419-", - "G11420-", - "A11421-", - "T11422-", - "T11423-", - "C11424-", - "G11425-", - "T11426-", - "T11427-", - "G11428-", - "A11429-", - "T11430-", - "G11431-", - "G11432-", - "C11433-", - "A11434-", - "A11435-", - "T11436-", - "G11437-", - "G11438-", - "T11439-", - "T11440-", - "A11441-", - "T11442-", - "A11443-", - "C11444-", - "A11445-", - "T11446-", - "G11447-", - "T11448-", - "A11449-", - "T11450-", - "A11451-", - "T11452-", - "C11453-", - "C11454-", - "G11455-", - "T11456-", - "T11457-", - "A11458-", - "T11459-", - "T11460-", - "T11461-", - "G11462-", - "A11463-", - "T11464-", - "C11465-", - "T11466-", - "A11467-", - "A11468-", - "T11469-", - "G11470-", - "T11471-", - "T11472-", - "G11473-", - "A11474-", - "C11475-", - "A11476-", - "T11477-", - "C11478-", - "T11479-", - "G11480-", - "A11481-", - "A11482-", - "C11483-", - "C11484-", - "G11485-", - "G11486-", - "A11487-", - "T11488-", - "T11489-", - "C11490-", - "T11491-", - "A11492-", - "G11493-", - "C11494-", - "A11495-", - "G11496-", - "T11497-", - "A11498-", - "A11499-", - "A11500-", - "G11501-", - "A11502-", - "T11503-", - "A11504-", - "C11505-", - "T11506-", - "A11507-", - "G11508-", - "A11509-", - "G11510-", - "A11511-", - "T11512-", - "T11513-", - "G11514-", - "T11515-", - "T11516-", - "T11517-", - "A11518-", - "T11519-", - "T11520-", - "A11521-", - "T11522-", - "A11523-", - "T11524-", - "C11525-", - "T11526-", - "A11527-", - "A11528-", - "C11529-", - "A11530-", - "G11531-", - "C11532-", - "C11533-", - "T11534-", - "T11535-", - "G11536-", - "T11537-", - "G11538-", - "A11539-", - "A11540-", - "G11541-", - "A11542-", - "A11543-", - "G11544-", - "T11545-", - "G11546-", - "T11547-", - "T11548-", - "T11549-", - "C11550-", - "T11551-", - "C11552-", - "C11553-", - "T11554-", - "C11555-", - "G11556-", - "T11557-", - "T11558-", - "T11559-", - "G11560-", - "T11561-", - "C11562-", - "A11563-", - "A11564-", - "T11565-", - "C11566-", - "A11567-", - "T11568-", - "G11569-", - "T11570-", - "T11571-", - "A11572-", - "A11573-", - "T11574-", - "G11575-", - "T11576-", - "C11577-", - "T11578-", - "T11579-", - "T11580-", - "A11581-", - "A11582-", - "G11583-", - "A11584-", - "T11585-", - "A11586-", - "A11587-", - "G11588-", - "G11589-", - "T11590-", - "A11591-", - "G11592-", - "A11593-", - "C11594-", - "A11595-", - "A11596-", - "A11597-", - "T11598-", - "G11599-", - "T11600-", - "T11601-", - "T11602-", - "A11603-", - "T11604-", - "A11605-", - "G11606-", - "T11607-", - "A11608-", - "C11609-", - "T11610-", - "A11611-", - "A11612-", - "G11613-", - "A11614-", - "A11615-", - "T11616-", - "T11617-", - "G11618-", - "G11619-", - "G11620-", - "C11621-", - "A11622-", - "A11623-", - "A11624-", - "C11625-", - "A11626-", - "T11627-", - "A11628-", - "A11629-", - "G11630-", - "A11631-", - "C11632-", - "A11633-", - "T11634-", - "G11635-", - "T11636-", - "C11637-", - "A11638-", - "C11639-", - "A11640-", - "A11641-", - "A11642-", - "G11643-", - "A11644-", - "C11645-", - "C11646-", - "C11647-", - "T11648-", - "T11649-", - "T11650-", - "T11651-", - "T11652-", - "G11653-", - "T11654-", - "A11655-", - "T11656-", - "G11657-", - "T11658-", - "A11659-", - "T11660-", - "A11661-", - "A11662-", - "G11663-", - "T11664-", - "G11665-", - "T11666-", - "A11667-", - "G11668-", - "A11669-", - "A11670-", - "A11671-", - "T11672-", - "T11673-", - "A11674-", - "T11675-", - "A11676-", - "A11677-", - "C11678-", - "A11679-", - "T11680-", - "C11681-", - "C11682-", - "A11683-", - "T11684-", - "A11685-", - "G11686-", - "T11687-", - "T11688-", - "G11689-", - "G11690-", - "A11691-", - "T11692-", - "T11693-", - "C11694-", - "A11695-", - "C11696-", - "A11697-", - "T11698-", - "A11699-", - "G11700-", - "G11701-", - "T11702-", - "G11703-", - "T11704-", - "C11705-", - "C11706-", - "A11707-", - "A11708-", - "T11709-", - "C11710-", - "G11711-", - "G11712-", - "G11713-", - "A11714-", - "T11715-", - "C11716-", - "T11717-", - "C11718-", - "T11719-", - "C11720-", - "C11721-", - "A11722-", - "T11723-", - "C11724-", - "A11725-", - "T11726-", - "C11727-", - "G11728-", - "A11729-", - "G11730-", - "A11731-", - "T11732-", - "G11733-", - "A11734-", - "T11735-", - "T11736-", - "G11737-", - "A11738-", - "C11739-", - "G11740-", - "G11741-", - "C11742-", - "A11743-", - "T11744-", - "C11745-", - "T11746-", - "C11747-", - "C11748-", - "C11749-", - "C11750-", - "C11751-", - "T11752-", - "T11753-", - "C11754-", - "C11755-", - "T11756-", - "T11757-", - "T11758-", - "T11759-", - "T11760-", - "T11761-", - "A11762-", - "G11763-", - "T11764-", - "A11765-", - "G11766-", - "A11767-", - "T11768-", - "A11769-", - "T11770-", - "T11771-", - "T11772-", - "C11773-", - "A11774-", - "T11775-", - "C11776-", - "G11777-", - "T11778-", - "G11779-", - "T11780-", - "A11781-", - "A11782-", - "G11783-", - "A11784-", - "A11785-", - "T11786-", - "C11787-", - "A11788-", - "A11789-", - "T11790-", - "A11791-", - "T11792-", - "T11793-", - "A11794-", - "A11795-", - "T11796-", - "A11797-", - "T11798-", - "T11799-", - "T11800-", - "C11801-", - "T11802-", - "A11803-", - "A11804-", - "A11805-", - "G11806-", - "T11807-", - "A11808-", - "T11809-", - "C11810-", - "T11811-", - "G11812-", - "T11813-", - "G11814-", - "T11815-", - "A11816-", - "T11817-", - "A11818-", - "G11819-", - "C11820-", - "C11821-", - "T11822-", - "C11823-", - "T11824-", - "T11825-", - "T11826-", - "A11827-", - "T11828-", - "T11829-", - "T11830-", - "A11831-", - "C11832-", - "C11833-", - "A11834-", - "C11835-", - "A11836-", - "G11837-", - "C11838-", - "T11839-", - "C11840-", - "C11841-", - "A11842-", - "T11843-", - "A11844-", - "T11845-", - "T11846-", - "C11847-", - "C11848-", - "A11849-", - "A11850-", - "C11851-", - "A11852-", - "T11853-", - "G11854-", - "C11855-", - "A11856-", - "T11857-", - "T11858-", - "C11859-", - "C11860-", - "A11861-", - "C11862-", - "T11863-", - "A11864-", - "G11865-", - "A11866-", - "G11867-", - "G11868-", - "G11869-", - "A11870-", - "T11871-", - "A11872-", - "T11873-", - "C11874-", - "G11875-", - "A11876-", - "T11877-", - "A11878-", - "T11879-", - "C11880-", - "G11881-", - "C11882-", - "C11883-", - "G11884-", - "A11885-", - "A11886-", - "T11887-", - "G11888-", - "T11889-", - "C11890-", - "A11891-", - "T11892-", - "A11893-", - "T11894-", - "A11895-", - "C11896-", - "T11897-", - "C11898-", - "A11899-", - "A11900-", - "T11901-", - "T11902-", - "A11903-", - "G11904-", - "T11905-", - "A11906-", - "T11907-", - "A11908-", - "T11909-", - "G11910-", - "T11911-", - "T11912-", - "G11913-", - "G11914-", - "A11915-", - "G11916-", - "G11917-", - "A11918-", - "C11919-", - "A11920-", - "T11921-", - "C11922-", - "C11923-", - "G11924-", - "A11925-", - "G11926-", - "T11927-", - "T11928-", - "C11929-", - "A11930-", - "T11931-", - "T11932-", - "G11933-", - "T11934-", - "T11935-", - "T11936-", - "T11937-", - "C11938-", - "A11939-", - "A11940-", - "T11941-", - "A11942-", - "T11943-", - "C11944-", - "A11945-", - "A11946-", - "A11947-", - "G11948-", - "A11949-", - "G11950-", - "A11951-", - "T11952-", - "G11953-", - "G11954-", - "T11955-", - "T11956-", - "T11957-", - "C11958-", - "C11959-", - "T11960-", - "T11961-", - "A11962-", - "T11963-", - "C11964-", - "A11965-", - "T11966-", - "T11967-", - "T11968-", - "C11969-", - "T11970-", - "C11971-", - "C11972-", - "A11973-", - "T11974-", - "A11975-", - "G11976-", - "T11977-", - "G11978-", - "G11979-", - "T11980-", - "A11981-", - "C11982-", - "A11983-", - "A11984-", - "T11985-", - "A11986-", - "C11987-", - "T11988-", - "A11989-", - "C11990-", - "A11991-", - "C11992-", - "A11993-", - "T11994-", - "T11995-", - "A11996-", - "T11997-", - "T11998-", - "C11999-", - "C12000-", - "G12001-", - "T12002-", - "A12003-", - "C12004-", - "G12005-", - "G12006-", - "C12007-", - "T12008-", - "T12009-", - "T12010-", - "C12011-", - "C12012-", - "A12013-", - "T12014-", - "T12015-", - "C12016-", - "T12017-", - "C12018-", - "C12019-", - "A12020-", - "A12021-", - "A12022-", - "A12023-", - "A12024-", - "C12025-", - "A12026-", - "A12027-", - "T12028-", - "T12029-", - "T12030-", - "T12031-", - "A12032-", - "C12033-", - "C12034-", - "A12035-", - "A12036-", - "A12037-", - "T12038-", - "C12039-", - "T12040-", - "A12041-", - "A12042-", - "A12043-", - "T12044-", - "C12045-", - "T12046-", - "A12047-", - "C12048-", - "A12049-", - "T12050-", - "C12051-", - "T12052-", - "T12053-", - "T12054-", - "A12055-", - "T12056-", - "T12057-", - "G12058-", - "T12059-", - "A12060-", - "T12061-", - "C12062-", - "T12063-", - "A12064-", - "T12065-", - "A12066-", - "A12067-", - "T12068-", - "C12069-", - "A12070-", - "C12071-", - "T12072-", - "A12073-", - "T12074-", - "T12075-", - "T12076-", - "A12077-", - "G12078-", - "A12079-", - "T12080-", - "A12081-", - "A12082-", - "T12083-", - "C12084-", - "A12085-", - "G12086-", - "C12087-", - "C12088-", - "A12089-", - "T12090-", - "A12091-", - "A12092-", - "T12093-", - "T12094-", - "C12095-", - "C12096-", - "T12097-", - "C12098-", - "G12099-", - "A12100-", - "G12101-", - "T12102-", - "G12103-", - "C12104-", - "A12105-", - "A12106-", - "C12107-", - "A12108-", - "T12109-", - "G12110-", - "T12111-", - "T12112-", - "A12113-", - "G12114-", - "A12115-", - "T12116-", - "C12117-", - "G12118-", - "T12119-", - "C12120-", - "T12121-", - "A12122-", - "T12123-", - "A12124-", - "T12125-", - "A12126-", - "T12127-", - "G12128-", - "A12129-", - "A12130-", - "T12131-", - "A12132-", - "A12133-", - "G12134-", - "C12135-", - "C12136-", - "G12137-", - "T12138-", - "G12139-", - "T12140-", - "T12141-", - "A12142-", - "T12143-", - "C12144-", - "T12145-", - "A12146-", - "T12147-", - "T12148-", - "C12149-", - "C12150-", - "T12151-", - "T12152-", - "T12153-", - "C12154-", - "A12155-", - "T12156-", - "T12157-", - "A12158-", - "A12159-", - "C12160-", - "A12161-", - "A12162-", - "T12163-", - "T12164-", - "T12165-", - "A12166-", - "A12167-", - "C12168-", - "G12169-", - "A12170-", - "T12171-", - "G12172-", - "T12173-", - "C12174-", - "T12175-", - "A12176-", - "T12177-", - "A12178-", - "T12179-", - "C12180-", - "T12181-", - "A12182-", - "T12183-", - "A12184-", - "T12185-", - "G12186-", - "A12187-", - "G12188-", - "A12189-", - "T12190-", - "G12191-", - "A12192-", - "C12193-", - "T12194-", - "T12195-", - "A12196-", - "A12197-", - "T12198-", - "A12199-", - "T12200-", - "A12201-", - "A12202-", - "T12203-", - "A12204-", - "T12205-", - "T12206-", - "G12207-", - "A12208-", - "A12209-", - "G12210-", - "A12211-", - "G12212-", - "C12213-", - "T12214-", - "G12215-", - "T12216-", - "A12217-", - "C12218-", - "A12219-", - "A12220-", - "T12221-", - "A12222-", - "G12223-", - "T12224-", - "T12225-", - "T12226-", - "T12227-", - "T12228-", - "A12229-", - "T12230-", - "C12231-", - "T12232-", - "A12233-", - "T12234-", - "A12235-", - "G12236-", - "A12237-", - "A12238-", - "G149818A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G151362A" - ], - "OPG023": [ - "S221X", - "S222-", - "I223-", - "D224-", - "K225-", - "N226-", - "Y227-", - "C228-", - "T229-", - "A230-", - "L231-", - "Q232-", - "Y233-", - "Y234-", - "I235-", - "K236-", - "S237-", - "S238-", - "H239-", - "I240-", - "D241-", - "I242-", - "D243-", - "I244-", - "V245-", - "K246-", - "L247-", - "L248-", - "M249-", - "K250-", - "G251-", - "I252-", - "D253-", - "N254-", - "T255-", - "A256-", - "Y257-", - "S258-", - "Y259-", - "I260-", - "D261-", - "D262-", - "L263-", - "T264-", - "C265-", - "C266-", - "T267-", - "R268-", - "G269-", - "I270-", - "M271-", - "A272-", - "D273-", - "Y274-", - "L275-", - "N276-", - "S277-", - "D278-", - "Y279-", - "R280-", - "Y281-", - "N282-", - "K283-", - "D284-", - "V285-", - "D286-", - "L287-", - "D288-", - "L289-", - "V290-", - "K291-", - "L292-", - "F293-", - "L294-", - "E295-", - "N296-", - "G297-", - "K298-", - "P299-", - "Y300-", - "G301-", - "I302-", - "M303-", - "C304-", - "S305-", - "I306-", - "V307-", - "P308-", - "L309-", - "W310-", - "R311-", - "N312-", - "D313-", - "K314-", - "E315-", - "T316-", - "I317-", - "S318-", - "L319-", - "I320-", - "L321-", - "K322-", - "T323-", - "M324-", - "N325-", - "S326-", - "D327-", - "V328-", - "L329-", - "Q330-", - "H331-", - "I332-", - "L333-", - "I334-", - "E335-", - "Y336-", - "M337-", - "T338-", - "F339-", - "G340-", - "D341-", - "I342-", - "D343-", - "I344-", - "P345-", - "L346-", - "V347-", - "E348-", - "C349-", - "M350-", - "L351-", - "E352-", - "Y353-", - "G354-", - "A355-", - "V356-", - "V357-", - "N358-", - "K359-", - "E360-", - "A361-", - "I362-", - "H363-", - "R364-", - "Y365-", - "F366-", - "R367-", - "N368-", - "I369-", - "N370-", - "I371-", - "D372-", - "S373-", - "Y374-", - "T375-", - "M376-", - "K377-", - "Y378-", - "L379-", - "L380-", - "K381-", - "K382-", - "E383-", - "G384-", - "G385-", - "D386-", - "A387-", - "V388-", - "N389-", - "H390-", - "L391-", - "D392-", - "D393-", - "G394-", - "E395-", - "I396-", - "P397-", - "I398-", - "G399-", - "H400-", - "L401-", - "C402-", - "E403-", - "S404-", - "N405-", - "Y406-", - "G407-", - "C408-", - "Y409-", - "N410-", - "F411-", - "Y412-", - "T413-", - "Y414-", - "T415-", - "Y416-", - "K417-", - "K418-", - "G419-", - "L420-", - "C421-", - "D422-", - "M423-", - "S424-", - "Y425-", - "V426-", - "C427-", - "P428-", - "I429-", - "L430-", - "S431-", - "T432-", - "I433-", - "N434-", - "I435-", - "C436-", - "L437-", - "P438-", - "Y439-", - "L440-", - "K441-", - "D442-", - "I443-", - "N444-", - "M445-", - "I446-", - "D447-", - "K448-", - "R449-", - "G450-", - "E451-", - "T452-", - "L453-", - "L454-", - "H455-", - "K456-", - "A457-", - "V458-", - "R459-", - "Y460-", - "N461-", - "K462-", - "Q463-", - "S464-", - "L465-", - "V466-", - "S467-", - "L468-", - "L469-", - "L470-", - "E471-", - "S472-", - "G473-", - "S474-", - "D475-", - "V476-", - "N477-", - "I478-", - "R479-", - "S480-", - "N481-", - "N482-", - "G483-", - "Y484-", - "T485-", - "C486-", - "I487-", - "T488-", - "I489-", - "A490-", - "I491-", - "N492-", - "E493-", - "S494-", - "R495-", - "N496-", - "I497-", - "E498-", - "L499-", - "L500-", - "K501-", - "M502-", - "L503-", - "L504-", - "C505-", - "H506-", - "K507-", - "P508-", - "T509-", - "L510-", - "D511-", - "C512-", - "V513-", - "I514-", - "D515-", - "S516-", - "L517-", - "S518-", - "E519-", - "V520-", - "S521-", - "N522-", - "I523-", - "V524-", - "D525-", - "*661X" - ], - "OPG176": [ - "D4N" - ] - }, - "labels": { - "aa": "OPG023: S221X, S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-, *661X; OPG176: D4N", - "clade": "B.1.15" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI018", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Stocker,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Stocker,H., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI018" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON694335" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A192404-", - "G192405-", - "T192406-", - "C192407-", - "A192408-", - "T192409-", - "A192410-", - "A192411-", - "G192412-", - "T192413-", - "T192414-", - "A192415-", - "G192416-", - "T192417-", - "T192418-", - "A192419-", - "A192420-", - "G192421-", - "T192422-", - "C192423-", - "A192424-", - "T192425-", - "A192426-", - "A192427-", - "G192428-", - "T192429-", - "T192430-", - "A192431-", - "G192432-", - "T192433-", - "T192434-", - "A192435-", - "A196604-" - ] - } - } - }, - { - "name": "Monkeypox/PT0129/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0129/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP324453" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-12" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594A", - "-595T", - "C18133T", - "-196601A", - "-196602A", - "-196603A", - "A196616T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI352", - "node_attrs": { - "div": 5, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI352" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP484673" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C21128T", - "G74187T", - "C151111T" - ], - "OPG037": [ - "E436K" - ], - "OPG094": [ - "Q136H" - ] - }, - "labels": { - "aa": "OPG037: E436K; OPG094: Q136H" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI561", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI561" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP764619" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000046", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C8385T", - "-11326A", - "-11327T", - "-11328C", - "-11329T", - "-11330A", - "-11331C", - "-11332G", - "-11333A", - "-11334T", - "-11335A", - "-11336T", - "-11337T", - "-11338A", - "-11339G", - "-11340A", - "-11341T", - "-11342A", - "-11343C", - "-11344T", - "-11345T", - "-11346C", - "-11347A", - "-11348C", - "-11349T", - "-11350C", - "-11351A", - "-11352A", - "-11353T", - "-11354G", - "-11355A", - "-11356A", - "-11357T", - "-11358C", - "-11359A", - "-11360A", - "-11361T", - "-11362C", - "-11363A", - "-11364C", - "-11365A", - "-11366C", - "-11367A", - "-11368A", - "-11369T", - "-11370C", - "-11371T", - "-11372A", - "-11373A", - "-11374T", - "-11375G", - "-11376T", - "-11377A", - "-11378G", - "-11379G", - "-11380T", - "-11381T", - "-11382T", - "-11383A", - "-11384T", - "-11385G", - "-11386A", - "-11387C", - "-11388A", - "-11389T", - "-11390A", - "-11391A", - "-11392T", - "-11393A", - "-11394G", - "-11395C", - "-11396A", - "-11397T", - "-11398T", - "-11399T", - "-11400T", - "-11401C", - "-11402A", - "-11403G", - "-11404C", - "-11405A", - "-11406G", - "-11407T", - "-11408T", - "-11409C", - "-11410A", - "-11411A", - "-11412T", - "-11413G", - "-11414T", - "-11415T", - "-11416T", - "-11417C", - "-11418T", - "-11419A", - "-11420G", - "-11421A", - "-11422T", - "-11423T", - "-11424C", - "-11425G", - "-11426T", - "-11427T", - "-11428G", - "-11429A", - "-11430T", - "-11431G", - "-11432G", - "-11433C", - "-11434A", - "-11435A", - "-11436T", - "-11437G", - "-11438G", - "-11439T", - "-11440T", - "-11441A", - "-11442T", - "-11443A", - "-11444C", - "-11445A", - "-11446T", - "-11447G", - "-11448T", - "-11449A", - "-11450T", - "-11451A", - "-11452T", - "-11453C", - "-11454C", - "-11455G", - "-11456T", - "-11457T", - "-11458A", - "-11459T", - "-11460T", - "-11461T", - "-11462G", - "-11463A", - "-11464T", - "-11465C", - "-11466T", - "-11467A", - "-11468A", - "-11469T", - "-11470G", - "-11471T", - "-11472T", - "-11473G", - "-11474A", - "-11475C", - "-11476A", - "-11477T", - "-11478C", - "-11479T", - "-11480G", - "-11481A", - "-11482A", - "-11483C", - "-11484C", - "-11485G", - "-11486G", - "-11487A", - "-11488T", - "-11489T", - "-11490C", - "-11491T", - "-11492A", - "-11493G", - "-11494C", - "-11495A", - "-11496G", - "-11497T", - "-11498A", - "-11499A", - "-11500A", - "-11501G", - "-11502A", - "-11503T", - "-11504A", - "-11505C", - "-11506T", - "-11507A", - "-11508G", - "-11509A", - "-11510G", - "-11511A", - "-11512T", - "-11513T", - "-11514G", - "-11515T", - "-11516T", - "-11517T", - "-11518A", - "-11519T", - "-11520T", - "-11521A", - "-11522T", - "-11523A", - "-11524T", - "-11525C", - "-11526T", - "-11527A", - "-11528A", - "-11529C", - "-11530A", - "-11531G", - "-11532C", - "-11533C", - "-11534T", - "-11535T", - "-11536G", - "-11537T", - "-11538G", - "-11539A", - "-11540A", - "-11541G", - "-11542A", - "-11543A", - "-11544G", - "-11545T", - "-11546G", - "-11547T", - "-11548T", - "-11549T", - "-11550C", - "-11551T", - "-11552C", - "-11553C", - "-11554T", - "-11555C", - "-11556G", - "-11557T", - "-11558T", - "-11559T", - "-11560G", - "-11561T", - "-11562C", - "-11563A", - "-11564A", - "-11565T", - "-11566C", - "-11567A", - "-11568T", - "-11569G", - "-11570T", - "-11571T", - "-11572A", - "-11573A", - "-11574T", - "-11575G", - "-11576T", - "-11577C", - "-11578T", - "-11579T", - "-11580T", - "-11581A", - "-11582A", - "-11583G", - "-11584A", - "-11585T", - "-11586A", - "-11587A", - "-11588G", - "-11589G", - "-11590T", - "-11591A", - "-11592G", - "-11593A", - "-11594C", - "-11595A", - "-11596A", - "-11597A", - "-11598T", - "-11599G", - "-11600T", - "-11601T", - "-11602T", - "-11603A", - "-11604T", - "-11605A", - "-11606G", - "-11607T", - "-11608A", - "-11609C", - "-11610T", - "-11611A", - "-11612A", - "-11613G", - "-11614A", - "-11615A", - "-11616T", - "-11617T", - "-11618G", - "-11619G", - "-11620G", - "-11621C", - "-11622A", - "-11623A", - "-11624A", - "-11625C", - "-11626A", - "-11627T", - "-11628A", - "-11629A", - "-11630G", - "-11631A", - "-11632C", - "-11633A", - "-11634T", - "-11635G", - "-11636T", - "-11637C", - "-11638A", - "-11639C", - "-11640A", - "-11641A", - "-11642A", - "-11643G", - "-11644A", - "-11645C", - "-11646C", - "-11647C", - "-11648T", - "-11649T", - "-11650T", - "-11651T", - "-11652T", - "-11653G", - "-11654T", - "-11655A", - "-11656T", - "-11657G", - "-11658T", - "-11659A", - "-11660T", - "-11661A", - "-11662A", - "-11663G", - "-11664T", - "-11665G", - "-11666T", - "-11667A", - "-11668G", - "-11669A", - "-11670A", - "-11671A", - "-11672T", - "-11673T", - "-11674A", - "-11675T", - "-11676A", - "-11677A", - "-11678C", - "-11679A", - "-11680T", - "-11681C", - "-11682C", - "-11683A", - "-11684T", - "-11685A", - "-11686G", - "-11687T", - "-11688T", - "-11689G", - "-11690G", - "-11691A", - "-11692T", - "-11693T", - "-11694C", - "-11695A", - "-11696C", - "-11697A", - "-11698T", - "-11699A", - "-11700G", - "-11701G", - "-11702T", - "-11703G", - "-11704T", - "-11705C", - "-11706C", - "-11707A", - "-11708A", - "-11709T", - "-11710C", - "-11711G", - "-11712G", - "-11713G", - "-11714A", - "-11715T", - "-11716C", - "-11717T", - "-11718C", - "-11719T", - "-11720C", - "-11721C", - "-11722A", - "-11723T", - "-11724C", - "-11725A", - "-11726T", - "-11727C", - "-11728G", - "-11729A", - "-11730G", - "-11731A", - "-11732T", - "-11733G", - "-11734A", - "-11735T", - "-11736T", - "-11737G", - "-11738A", - "-11739C", - "-11740G", - "-11741G", - "-11742C", - "-11743A", - "-11744T", - "-11745C", - "-11746T", - "-11747C", - "-11748C", - "-11749C", - "-11750C", - "-11751C", - "-11752T", - "-11753T", - "-11754C", - "-11755C", - "-11756T", - "-11757T", - "-11758T", - "-11759T", - "-11760T", - "-11761T", - "-11762A", - "-11763G", - "-11764T", - "-11765A", - "-11766G", - "-11767A", - "-11768T", - "-11769A", - "-11770T", - "-11771T", - "-11772T", - "-11773C", - "-11774A", - "-11775T", - "-11776C", - "-11777G", - "-11778T", - "-11779G", - "-11780T", - "-11781A", - "-11782A", - "-11783G", - "-11784A", - "-11785A", - "-11786T", - "-11787C", - "-11788A", - "-11789A", - "-11790T", - "-11791A", - "-11792T", - "-11793T", - "-11794A", - "-11795A", - "-11796T", - "-11797A", - "-11798T", - "-11799T", - "-11800T", - "-11801C", - "-11802T", - "-11803A", - "-11804A", - "-11805A", - "-11806G", - "-11807T", - "-11808A", - "-11809T", - "-11810C", - "-11811T", - "-11812G", - "-11813T", - "-11814G", - "-11815T", - "-11816A", - "-11817T", - "-11818A", - "-11819G", - "-11820C", - "-11821C", - "-11822T", - "-11823C", - "-11824T", - "-11825T", - "-11826T", - "-11827A", - "-11828T", - "-11829T", - "-11830T", - "-11831A", - "-11832C", - "-11833C", - "-11834A", - "-11835C", - "-11836A", - "-11837G", - "-11838C", - "-11839T", - "-11840C", - "-11841C", - "-11842A", - "-11843T", - "-11844A", - "-11845T", - "-11846T", - "-11847C", - "-11848C", - "-11849A", - "-11850A", - "-11851C", - "-11852A", - "-11853T", - "-11854G", - "-11855C", - "-11856A", - "-11857T", - "-11858T", - "-11859C", - "-11860C", - "-11861A", - "-11862C", - "-11863T", - "-11864A", - "-11865G", - "-11866A", - "-11867G", - "-11868G", - "-11869G", - "-11870A", - "-11871T", - "-11872A", - "-11873T", - "-11874C", - "-11875G", - "-11876A", - "-11877T", - "-11878A", - "-11879T", - "-11880C", - "-11881G", - "-11882C", - "-11883C", - "-11884G", - "-11885A", - "-11886A", - "-11887T", - "-11888G", - "-11889T", - "-11890C", - "-11891A", - "-11892T", - "-11893A", - "-11894T", - "-11895A", - "-11896C", - "-11897T", - "-11898C", - "-11899A", - "-11900A", - "-11901T", - "-11902T", - "-11903A", - "-11904G", - "-11905T", - "-11906A", - "-11907T", - "-11908A", - "-11909T", - "-11910G", - "-11911T", - "-11912T", - "-11913G", - "-11914G", - "-11915A", - "-11916G", - "-11917G", - "-11918A", - "-11919C", - "-11920A", - "-11921T", - "-11922C", - "-11923C", - "-11924G", - "-11925A", - "-11926G", - "-11927T", - "-11928T", - "-11929C", - "-11930A", - "-11931T", - "-11932T", - "-11933G", - "-11934T", - "-11935T", - "-11936T", - "-11937T", - "-11938C", - "-11939A", - "-11940A", - "-11941T", - "-11942A", - "-11943T", - "-11944C", - "-11945A", - "-11946A", - "-11947A", - "-11948G", - "-11949A", - "-11950G", - "-11951A", - "-11952T", - "-11953G", - "-11954G", - "-11955T", - "-11956T", - "-11957T", - "-11958C", - "-11959C", - "-11960T", - "-11961T", - "-11962A", - "-11963T", - "-11964C", - "-11965A", - "-11966T", - "-11967T", - "-11968T", - "-11969C", - "-11970T", - "-11971C", - "-11972C", - "-11973A", - "-11974T", - "-11975A", - "-11976G", - "-11977T", - "-11978G", - "-11979G", - "-11980T", - "-11981A", - "-11982C", - "-11983A", - "-11984A", - "-11985T", - "-11986A", - "-11987C", - "-11988T", - "-11989A", - "-11990C", - "-11991A", - "-11992C", - "-11993A", - "-11994T", - "-11995T", - "-11996A", - "-11997T", - "-11998T", - "-11999C", - "-12000C", - "-12001G", - "-12002T", - "-12003A", - "-12004C", - "-12005G", - "-12006G", - "-12007C", - "-12008T", - "-12009T", - "-12010T", - "-12011C", - "-12012C", - "-12013A", - "-12014T", - "-12015T", - "-12016C", - "-12017T", - "-12018C", - "-12019C", - "-12020A", - "-12021A", - "-12022A", - "-12023A", - "-12024A", - "-12025C", - "-12026A", - "-12027A", - "-12028T", - "-12029T", - "-12030T", - "-12031T", - "-12032A", - "-12033C", - "-12034C", - "-12035A", - "-12036A", - "-12037A", - "-12038T", - "-12039C", - "-12040T", - "-12041A", - "-12042A", - "-12043A", - "-12044T", - "-12045C", - "-12046T", - "-12047A", - "-12048C", - "-12049A", - "-12050T", - "-12051C", - "-12052T", - "-12053T", - "-12054T", - "-12055A", - "-12056T", - "-12057T", - "-12058G", - "-12059T", - "-12060A", - "-12061T", - "-12062C", - "-12063T", - "-12064A", - "-12065T", - "-12066A", - "-12067A", - "-12068T", - "-12069C", - "-12070A", - "-12071C", - "-12072T", - "-12073A", - "-12074T", - "-12075T", - "-12076T", - "-12077A", - "-12078G", - "-12079A", - "-12080T", - "-12081A", - "-12082A", - "-12083T", - "-12084C", - "-12085A", - "-12086G", - "-12087C", - "-12088C", - "-12089A", - "-12090T", - "-12091A", - "-12092A", - "-12093T", - "-12094T", - "-12095C", - "-12096C", - "-12097T", - "-12098C", - "-12099G", - "-12100A", - "-12101G", - "-12102T", - "-12103G", - "-12104C", - "-12105A", - "-12106A", - "-12107C", - "-12108A", - "-12109T", - "-12110G", - "-12111T", - "-12112T", - "-12113A", - "-12114G", - "-12115A", - "-12116T", - "-12117C", - "-12118G", - "-12119T", - "-12120C", - "-12121T", - "-12122A", - "-12123T", - "-12124A", - "-12125T", - "-12126A", - "-12127T", - "-12128G", - "-12129A", - "-12130A", - "-12131T", - "-12132A", - "-12133A", - "-12134G", - "-12135C", - "-12136C", - "-12137G", - "-12138T", - "-12139G", - "-12140T", - "-12141T", - "-12142A", - "-12143T", - "-12144C", - "-12145T", - "-12146A", - "-12147T", - "-12148T", - "-12149C", - "-12150C", - "-12151T", - "-12152T", - "-12153T", - "-12154C", - "-12155A", - "-12156T", - "-12157T", - "-12158A", - "-12159A", - "-12160C", - "-12161A", - "-12162A", - "-12163T", - "-12164T", - "-12165T", - "-12166A", - "-12167A", - "-12168C", - "-12169G", - "-12170A", - "-12171T", - "-12172G", - "-12173T", - "-12174C", - "-12175T", - "-12176A", - "-12177T", - "-12178A", - "-12179T", - "-12180C", - "-12181T", - "-12182A", - "-12183T", - "-12184A", - "-12185T", - "-12186G", - "-12187A", - "-12188G", - "-12189A", - "-12190T", - "-12191G", - "-12192A", - "-12193C", - "-12194T", - "-12195T", - "-12196A", - "-12197A", - "-12198T", - "-12199A", - "-12200T", - "-12201A", - "-12202A", - "-12203T", - "-12204A", - "-12205T", - "-12206T", - "-12207G", - "-12208A", - "-12209A", - "-12210G", - "-12211A", - "-12212G", - "-12213C", - "-12214T", - "-12215G", - "-12216T", - "-12217A", - "-12218C", - "-12219A", - "-12220A", - "-12221T", - "-12222A", - "-12223G", - "-12224T", - "-12225T", - "-12226T", - "-12227T", - "-12228T", - "-12229A", - "-12230T", - "-12231C", - "-12232T", - "-12233A", - "-12234T", - "-12235A", - "-12236G", - "-12237A", - "-12238A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG023": [ - "X221S", - "-222S", - "-223I", - "-224D", - "-225K", - "-226N", - "-227Y", - "-228C", - "-229T", - "-230A", - "-231L", - "-232Q", - "-233Y", - "-234Y", - "-235I", - "-236K", - "-237S", - "-238S", - "-239H", - "-240I", - "-241D", - "-242I", - "-243D", - "-244I", - "-245V", - "-246K", - "-247L", - "-248L", - "-249M", - "-250K", - "-251G", - "-252I", - "-253D", - "-254N", - "-255T", - "-256A", - "-257Y", - "-258S", - "-259Y", - "-260I", - "-261D", - "-262D", - "-263L", - "-264T", - "-265C", - "-266C", - "-267T", - "-268R", - "-269G", - "-270I", - "-271M", - "-272A", - "-273D", - "-274Y", - "-275L", - "-276N", - "-277S", - "-278D", - "-279Y", - "-280R", - "-281Y", - "-282N", - "-283K", - "-284D", - "-285V", - "-286D", - "-287L", - "-288D", - "-289L", - "-290V", - "-291K", - "-292L", - "-293F", - "-294L", - "-295E", - "-296N", - "-297G", - "-298K", - "-299P", - "-300Y", - "-301G", - "-302I", - "-303M", - "-304C", - "-305S", - "-306I", - "-307V", - "-308P", - "-309L", - "-310W", - "-311R", - "-312N", - "-313D", - "-314K", - "-315E", - "-316T", - "-317I", - "-318S", - "-319L", - "-320I", - "-321L", - "-322K", - "-323T", - "-324M", - "-325N", - "-326S", - "-327D", - "-328V", - "-329L", - "-330Q", - "-331H", - "-332I", - "-333L", - "-334I", - "-335E", - "-336Y", - "-337M", - "-338T", - "-339F", - "-340G", - "-341D", - "-342I", - "-343D", - "-344I", - "-345P", - "-346L", - "-347V", - "-348E", - "-349C", - "-350M", - "-351L", - "-352E", - "-353Y", - "-354G", - "-355A", - "-356V", - "-357V", - "-358N", - "-359K", - "-360E", - "-361A", - "-362I", - "-363H", - "-364R", - "-365Y", - "-366F", - "-367R", - "-368N", - "-369I", - "-370N", - "-371I", - "-372D", - "-373S", - "-374Y", - "-375T", - "-376M", - "-377K", - "-378Y", - "-379L", - "-380L", - "-381K", - "-382K", - "-383E", - "-384G", - "-385G", - "-386D", - "-387A", - "-388V", - "-389N", - "-390H", - "-391L", - "-392D", - "-393D", - "-394G", - "-395E", - "-396I", - "-397P", - "-398I", - "-399G", - "-400H", - "-401L", - "-402C", - "-403E", - "-404S", - "-405N", - "-406Y", - "-407G", - "-408C", - "-409Y", - "-410N", - "-411F", - "-412Y", - "-413T", - "-414Y", - "-415T", - "-416Y", - "-417K", - "-418K", - "-419G", - "-420L", - "-421C", - "-422D", - "-423M", - "-424S", - "-425Y", - "-426V", - "-427C", - "-428P", - "-429I", - "-430L", - "-431S", - "-432T", - "-433I", - "-434N", - "-435I", - "-436C", - "-437L", - "-438P", - "-439Y", - "-440L", - "-441K", - "-442D", - "-443I", - "-444N", - "-445M", - "-446I", - "-447D", - "-448K", - "-449R", - "-450G", - "-451E", - "-452T", - "-453L", - "-454L", - "-455H", - "-456K", - "-457A", - "-458V", - "-459R", - "-460Y", - "-461N", - "-462K", - "-463Q", - "-464S", - "-465L", - "-466V", - "-467S", - "-468L", - "-469L", - "-470L", - "-471E", - "-472S", - "-473G", - "-474S", - "-475D", - "-476V", - "-477N", - "-478I", - "-479R", - "-480S", - "-481N", - "-482N", - "-483G", - "-484Y", - "-485T", - "-486C", - "-487I", - "-488T", - "-489I", - "-490A", - "-491I", - "-492N", - "-493E", - "-494S", - "-495R", - "-496N", - "-497I", - "-498E", - "-499L", - "-500L", - "-501K", - "-502M", - "-503L", - "-504L", - "-505C", - "-506H", - "-507K", - "-508P", - "-509T", - "-510L", - "-511D", - "-512C", - "-513V", - "-514I", - "-515D", - "-516S", - "-517L", - "-518S", - "-519E", - "-520V", - "-521S", - "-522N", - "-523I", - "-524V", - "-525D", - "X661*" - ] - }, - "labels": { - "aa": "OPG023: X221S, -222S, -223I, -224D, -225K, -226N, -227Y, -228C, -229T, -230A, -231L, -232Q, -233Y, -234Y, -235I, -236K, -237S, -238S, -239H, -240I, -241D, -242I, -243D, -244I, -245V, -246K, -247L, -248L, -249M, -250K, -251G, -252I, -253D, -254N, -255T, -256A, -257Y, -258S, -259Y, -260I, -261D, -262D, -263L, -264T, -265C, -266C, -267T, -268R, -269G, -270I, -271M, -272A, -273D, -274Y, -275L, -276N, -277S, -278D, -279Y, -280R, -281Y, -282N, -283K, -284D, -285V, -286D, -287L, -288D, -289L, -290V, -291K, -292L, -293F, -294L, -295E, -296N, -297G, -298K, -299P, -300Y, -301G, -302I, -303M, -304C, -305S, -306I, -307V, -308P, -309L, -310W, -311R, -312N, -313D, -314K, -315E, -316T, -317I, -318S, -319L, -320I, -321L, -322K, -323T, -324M, -325N, -326S, -327D, -328V, -329L, -330Q, -331H, -332I, -333L, -334I, -335E, -336Y, -337M, -338T, -339F, -340G, -341D, -342I, -343D, -344I, -345P, -346L, -347V, -348E, -349C, -350M, -351L, -352E, -353Y, -354G, -355A, -356V, -357V, -358N, -359K, -360E, -361A, -362I, -363H, -364R, -365Y, -366F, -367R, -368N, -369I, -370N, -371I, -372D, -373S, -374Y, -375T, -376M, -377K, -378Y, -379L, -380L, -381K, -382K, -383E, -384G, -385G, -386D, -387A, -388V, -389N, -390H, -391L, -392D, -393D, -394G, -395E, -396I, -397P, -398I, -399G, -400H, -401L, -402C, -403E, -404S, -405N, -406Y, -407G, -408C, -409Y, -410N, -411F, -412Y, -413T, -414Y, -415T, -416Y, -417K, -418K, -419G, -420L, -421C, -422D, -423M, -424S, -425Y, -426V, -427C, -428P, -429I, -430L, -431S, -432T, -433I, -434N, -435I, -436C, -437L, -438P, -439Y, -440L, -441K, -442D, -443I, -444N, -445M, -446I, -447D, -448K, -449R, -450G, -451E, -452T, -453L, -454L, -455H, -456K, -457A, -458V, -459R, -460Y, -461N, -462K, -463Q, -464S, -465L, -466V, -467S, -468L, -469L, -470L, -471E, -472S, -473G, -474S, -475D, -476V, -477N, -478I, -479R, -480S, -481N, -482N, -483G, -484Y, -485T, -486C, -487I, -488T, -489I, -490A, -491I, -492N, -493E, -494S, -495R, -496N, -497I, -498E, -499L, -500L, -501K, -502M, -503L, -504L, -505C, -506H, -507K, -508P, -509T, -510L, -511D, -512C, -513V, -514I, -515D, -516S, -517L, -518S, -519E, -520V, -521S, -522N, -523I, -524V, -525D, X661*" - } - }, - "children": [ - { - "name": "MPXV/UZ_REGA_204/Belgium/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_204/Belgium/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR087013" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-08" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A86934G", - "G91904A", - "T133078-", - "T133079-", - "T149487-", - "A149488-", - "C149489-", - "G149490-", - "T149491-", - "T149492-", - "G149493-", - "A149494-", - "A149495-", - "C149496-", - "A149497-", - "A149498-", - "G149499-", - "T149500-", - "C149501-", - "C149502-", - "A149503-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG175": [ - "Y16-", - "V17-", - "E18-", - "Q19-", - "V20-", - "H21X", - "*126X" - ] - }, - "labels": { - "aa": "OPG175: Y16-, V17-, E18-, Q19-, V20-, H21X, *126X" - } - } - }, - { - "name": "NODE_0000047", - "node_attrs": { - "div": 7, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G40242A", - "C40335T", - "C127609T", - "G139582A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-" - ], - "OPG058": [ - "E34K" - ] - }, - "labels": { - "aa": "OPG058: E34K" - } - }, - "children": [ - { - "name": "BOL-UNIMOL-MPX-292803-L", - "node_attrs": { - "div": 7, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "strain_original": { - "value": "BOL-UNIMOL-MPX-292803-L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP390175" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-02" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-22751-L", - "node_attrs": { - "div": 10, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-22751-L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP431400" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-17" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G47482A", - "C60062T", - "G125388A", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ], - "OPG080": [ - "E653K" - ], - "OPG145": [ - "R481H" - ] - }, - "labels": { - "aa": "OPG080: E653K; OPG145: R481H" - } - } - }, - { - "name": "MET_INS_MPX_0956_C", - "node_attrs": { - "div": 9, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "strain_original": { - "value": "MET_INS_MPX_0956_C" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP819950" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-12" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G144284A", - "C171808T", - "A196376-", - "T196377-", - "C196378-" - ], - "OPG165": [ - "D257N" - ], - "OPG199": [ - "S274L" - ] - }, - "labels": { - "aa": "OPG165: D257N; OPG199: S274L" - } - } - }, - { - "name": "CES-UNIMOL-MPX-202203853-L", - "node_attrs": { - "div": 7, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "strain_original": { - "value": "CES-UNIMOL-MPX-202203853-L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP959067" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-15" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/UZ_REGA_163/Belgium/2022", - "node_attrs": { - "div": 12, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_163/Belgium/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR086972" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-27" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G31180A", - "C142626T", - "G158549A", - "G159341A", - "C170750T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG163": [ - "S142L" - ], - "OPG185": [ - "G142E" - ], - "OPG198": [ - "A238V" - ] - }, - "labels": { - "aa": "OPG163: S142L; OPG185: G142E; OPG198: A238V" - } - } - }, - { - "name": "NODE_0000048", - "node_attrs": { - "div": 8, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C21324T" - ] - } - }, - "children": [ - { - "name": "DC_INS_MPX_1024_L", - "node_attrs": { - "div": 11, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "strain_original": { - "value": "DC_INS_MPX_1024_L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP837479" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-20" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T509-", - "T510-", - "A511-", - "G68296A", - "C144166T", - "C181495T" - ], - "OPG085": [ - "S79L" - ], - "OPG210": [ - "S47L" - ] - }, - "labels": { - "aa": "OPG085: S79L; OPG210: S47L" - } - } - }, - { - "name": "MPXV/UZ_REGA_115", - "node_attrs": { - "div": 9, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_115" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035721" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-28" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "G180556A", - "T195509-", - "A195510-", - "A195511-" - ] - } - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000049", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G175093A", - "-179091C", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG204": [ - "D188N" - ] - }, - "labels": { - "aa": "OPG204: D188N", - "clade": "B.1.13" - } - }, - "children": [ - { - "name": "hMPX/Human/USA/CA-LACPHL-MA00096/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "strain_original": { - "value": "hMPX/Human/USA/CA-LACPHL-MA00096/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP442564" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-02" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C533-", - "A534-", - "T535-", - "C55472T", - "G55632A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "G167713A", - "C179091-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ], - "OPG074": [ - "D552N" - ], - "OPG193": [ - "R127K" - ] - }, - "labels": { - "aa": "OPG074: D552N; OPG193: R127K" - } - } - }, - { - "name": "MPXV-USA-IL-IDPH-002", - "node_attrs": { - "div": 3, - "author": { - "author": "Gagnon,K.T.", - "value": "Gagnon,K.T." - }, - "strain_original": { - "value": "MPXV-USA-IL-IDPH-002" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536663" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-04" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "G119424A", - "G125452A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-196601A", - "-196602A", - "-196603A" - ], - "OPG136": [ - "S55L" - ], - "OPG146": [ - "S63L" - ] - }, - "labels": { - "aa": "OPG136: S55L; OPG146: S63L" - } - } - }, - { - "name": "NODE_0000050", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G22814A", - "G55162A", - "C118921T", - "G137128A", - "G167910A", - "A173274-", - "T173275-" - ], - "OPG038": [ - "H116Y" - ], - "OPG074": [ - "S655L" - ], - "OPG136": [ - "D223N" - ], - "OPG193": [ - "E193K" - ] - }, - "labels": { - "aa": "OPG038: H116Y; OPG074: S655L; OPG136: D223N; OPG193: E193K" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_KS0004", - "node_attrs": { - "div": 6, - "author": { - "author": "Gigante,C., Bradley,A., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Sheth,M.R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Anderson,J., Li,Y.", - "value": "Gigante,C., Bradley,A., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Sheth,M.R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Anderson,J., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_KS0004" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ320456" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-XX" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A" - ] - } - } - }, - { - "name": "MPXV_USA_2022_KS0005", - "node_attrs": { - "div": 7, - "author": { - "author": "Gigante,C., Bradley,A., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Anderson,J., Li,Y.", - "value": "Gigante,C., Bradley,A., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Anderson,J., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_KS0005" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ721921" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C110297T", - "A173276-", - "T173277-", - "A179074-", - "T179075-", - "G179076-", - "C179091-", - "C179100-" - ] - } - } - } - ] - }, - { - "name": "NODE_0000051", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C132520T" - ] - } - }, - "children": [ - { - "name": "MpxV/human/USA/OH-UW-073812/2022", - "node_attrs": { - "div": 2, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "strain_original": { - "value": "MpxV/human/USA/OH-UW-073812/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP257254" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A" - ] - } - } - }, - { - "name": "NY-NYCPHL-001133", - "node_attrs": { - "div": 4, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-001133" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468592" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-06" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A31053G", - "G131867A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A" - ], - "OPG047": [ - "C48R" - ], - "OPG151": [ - "E982K" - ] - }, - "labels": { - "aa": "OPG047: C48R; OPG151: E982K" - } - } - }, - { - "name": "NODE_0000052", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C182950T" - ], - "OPG210": [ - "S532L" - ] - }, - "labels": { - "aa": "OPG210: S532L" - } - }, - "children": [ - { - "name": "MPXV-USA-IL-IDPH-016", - "node_attrs": { - "div": 3, - "author": { - "author": "Gagnon,K.T.", - "value": "Gagnon,K.T." - }, - "strain_original": { - "value": "MPXV-USA-IL-IDPH-016" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536677" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-05" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-196601A", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "hMpxV/USA/IL-RIPHL-MPXV-052-0034/2023", - "node_attrs": { - "div": 9, - "author": { - "author": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S.", - "value": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S." - }, - "strain_original": { - "value": "hMpxV/USA/IL-RIPHL-MPXV-052-0034/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR160418" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-05-10" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C27520T", - "G58883A", - "G99832A", - "G102186A", - "G129583A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G171410A", - "C179091-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ], - "OPG043": [ - "A146T" - ], - "OPG118": [ - "D463N" - ], - "OPG121": [ - "E133K" - ] - }, - "labels": { - "aa": "OPG043: A146T; OPG118: D463N; OPG121: E133K" - } - } - } - ] - }, - { - "name": "NODE_0000053", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G165086A", - "C179091-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-" - ] - } - }, - "children": [ - { - "name": "MPXV_USA_2022_IL0023", - "node_attrs": { - "div": 4, - "author": { - "author": "Gigante,C.M., Ghinai,I., Seabolt,M.H., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Kerins,J., Li,Y.", - "value": "Gigante,C.M., Ghinai,I., Seabolt,M.H., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Kerins,J., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_IL0023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP225966" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G70190A" - ], - "OPG089": [ - "E109K" - ] - }, - "labels": { - "aa": "OPG089: E109K" - } - } - }, - { - "name": "MPXV_USA_2022_KY0001", - "node_attrs": { - "div": 5, - "author": { - "author": "Gigante,C.M., Winter,K., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Arora,V., Li,Y.", - "value": "Gigante,C.M., Winter,K., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Arora,V., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_KY0001" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP303788" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C43238T", - "G101775A" - ], - "OPG063": [ - "D151N" - ] - }, - "labels": { - "aa": "OPG063: D151N" - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-082670/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-082670/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP310053" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C169529T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179154C", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T" - ] - } - } - } - ] - }, - { - "name": "NODE_0000054", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C21383T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G" - ], - "OPG037": [ - "G351S" - ] - }, - "labels": { - "aa": "OPG037: G351S" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/ON/RKI681", - "node_attrs": { - "div": 5, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI681" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ319139" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C24584T", - "G27462A", - "G150550-", - "A152668-", - "T152680-", - "T178896-", - "T178897-", - "A178898-", - "C178899-", - "A178900-", - "A178901-", - "G178902-", - "A178903-", - "T178904-", - "A178905-", - "C178906-", - "A178907-", - "T178908-", - "T178909-", - "T178910-", - "A178911-", - "A178912-", - "T178913-", - "G178914-", - "T178915-", - "G178916-", - "C178917-", - "T178918-", - "T178919-", - "A178920-", - "C178921-", - "G178922-", - "G178923-", - "A178924-", - "A178925-", - "C178926-", - "A178927-", - "T178928-", - "A178929-", - "T178930-", - "A178931-", - "T178932-", - "T178933-", - "T178934-", - "A178935-", - "G178936-", - "A178937-", - "A178938-", - "A178939-", - "C178940-", - "A178941-", - "T178942-", - "C178943-", - "T178944-", - "A178945-", - "C178946-", - "T178947-", - "A178948-", - "A178949-", - "C178950-", - "G178951-", - "A178952-", - "T178953-", - "T178954-", - "T178955-", - "T178956-", - "T178957-", - "T178958-", - "A178959-", - "T178960-", - "G178961-", - "C178962-", - "T178963-", - "T178964-", - "G178965-", - "T178966-", - "A178967-" - ], - "OPG040": [ - "D299N" - ], - "OPG043": [ - "S165L" - ] - }, - "labels": { - "aa": "OPG040: D299N; OPG043: S165L" - } - } - }, - { - "name": "NODE_0000055", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G85431A", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179091-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ], - "OPG106": [ - "S23F" - ] - }, - "labels": { - "aa": "OPG106: S23F" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI287", - "node_attrs": { - "div": 5, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Friesen,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Friesen,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI287" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP270476" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C172851T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI901", - "node_attrs": { - "div": 6, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI901" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773520" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C146446T", - "C147140T" - ], - "OPG170": [ - "M111I" - ] - }, - "labels": { - "aa": "OPG170: M111I" - } - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000056", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G12169A" - ] - } - }, - "children": [ - { - "name": "MPXV-USA-IL-IDPH-004", - "node_attrs": { - "div": 2, - "author": { - "author": "Gagnon,K.T.", - "value": "Gagnon,K.T." - }, - "strain_original": { - "value": "MPXV-USA-IL-IDPH-004" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536665" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-14" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "C25644T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196601A", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "NODE_0000057", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G44960A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - }, - "labels": { - "clade": "B.1.17" - } - }, - "children": [ - { - "name": "hMPX/Human/USA/CA-LACPHL-MA00051/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Hemarajata,P., Green,N.M.", - "value": "Hemarajata,P., Green,N.M." - }, - "strain_original": { - "value": "hMPX/Human/USA/CA-LACPHL-MA00051/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP440533" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-20" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C60079T" - ], - "OPG080": [ - "R647K" - ] - }, - "labels": { - "aa": "OPG080: R647K" - } - } - }, - { - "name": "hMPX/Human/USA/CA-LACPHL-MA00085/2022", - "node_attrs": { - "div": 2, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "strain_original": { - "value": "hMPX/Human/USA/CA-LACPHL-MA00085/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP442552" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-13" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G472-", - "A473-", - "T474-", - "A196429-", - "G196430-", - "A196431-" - ] - } - } - }, - { - "name": "Monkeypox virus/Human/USA/CA-LACPHL-MA00282/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "Monkeypox virus/Human/USA/CA-LACPHL-MA00282/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP748968" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-13" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A479-", - "T480-", - "A481-", - "G39327A", - "A136513-", - "T136514-", - "C136515-", - "A136516-", - "T136517-", - "C136518-", - "G140635A", - "A196429-", - "G196430-", - "A196431-" - ], - "OPG057": [ - "A290V" - ], - "OPG153": [ - "D384-", - "D385-" - ], - "OPG160": [ - "S147L" - ] - }, - "labels": { - "aa": "OPG057: A290V; OPG153: D384-, D385-; OPG160: S147L" - } - } - }, - { - "name": "NY-NYCPHL-000390", - "node_attrs": { - "div": 3, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000390" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468974" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-19" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G74262T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179154C", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG094": [ - "E161D" - ] - }, - "labels": { - "aa": "OPG094: E161D" - } - } - }, - { - "name": "NODE_0000058", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A11836G", - "G69249A", - "C113363T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "G171959A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179154C", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG132": [ - "D60N" - ] - }, - "labels": { - "aa": "OPG132: D60N" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-085171/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-085171/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP392546" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/USA/WA-UW-084166/2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-084166/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP628456" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C12850T" - ] - } - } - } - ] - }, - { - "name": "NODE_0000059", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G580-", - "A581-", - "G582-", - "C39334G", - "-150567T", - "T196584-", - "C196585-", - "A196586-" - ], - "OPG057": [ - "A288P" - ] - }, - "labels": { - "aa": "OPG057: A288P" - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00332/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00332/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP890560" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-09" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00308/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00308/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP890565" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-09" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000060", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150567T", - "C177626T" - ] - } - }, - "children": [ - { - "name": "hMPX/USA/CA-LACPHL-MA00179/2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "hMPX/USA/CA-LACPHL-MA00179/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP580612" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-20" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A577-", - "A578-", - "A579-", - "G16986A", - "T73740A", - "G73745A", - "T126985C", - "A140156G" - ], - "OPG093": [ - "F255I", - "M256I" - ], - "OPG159": [ - "N130S" - ] - }, - "labels": { - "aa": "OPG093: F255I, M256I; OPG159: N130S" - } - } - }, - { - "name": "Monkeypox virus/Human/USA/CA-LACPHL-MA00262/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "Monkeypox virus/Human/USA/CA-LACPHL-MA00262/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP748948" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-21" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T528-", - "G529-", - "A530-", - "G165305A" - ], - "OPG190": [ - "E62K" - ] - }, - "labels": { - "aa": "OPG190: E62K" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00483/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Hemarajata,P., Garrigues,J.M., Green,N.M.", - "value": "Hemarajata,P., Garrigues,J.M., Green,N.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00483/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ888843" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-13" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T39397C", - "G86148A" - ], - "OPG057": [ - "N267D" - ] - }, - "labels": { - "aa": "OPG057: N267D" - } - } - } - ] - }, - { - "name": "NODE_0000061", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T39394-", - "A39395-", - "T39396-", - "C85931T", - "-150567T" - ], - "OPG057": [ - "N267X", - "R268X", - "*373X" - ] - }, - "labels": { - "aa": "OPG057: N267X, R268X, *373X" - } - }, - "children": [ - { - "name": "Monkeypox virus/Human/USA/CA-LACPHL-MA00391/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "Monkeypox virus/Human/USA/CA-LACPHL-MA00391/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ330999" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-12-19" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C174129T" - ] - } - } - }, - { - "name": "NODE_0000062", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G182189A" - ] - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00426/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00426/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503819" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-12-14" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C177509T", - "C177703T" - ], - "OPG205": [ - "S683L" - ] - }, - "labels": { - "aa": "OPG205: S683L" - } - } - }, - { - "name": "NODE_0000063", - "node_attrs": { - "div": 5, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G71249A" - ], - "OPG090": [ - "R24Q" - ] - }, - "labels": { - "aa": "OPG090: R24Q" - } - }, - "children": [ - { - "name": "hMpxV/USA/CACDPH1MPX1000184/2023", - "node_attrs": { - "div": 6, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J." - }, - "strain_original": { - "value": "hMpxV/USA/CACDPH1MPX1000184/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ547899" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-01-10" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G172895A" - ] - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00478/2023", - "node_attrs": { - "div": 7, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00478/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ644784" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-01-08" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A11160G", - "T133529G" - ], - "OPG023": [ - "F581L" - ] - }, - "labels": { - "aa": "OPG023: F581L" - } - } - } - ] - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000064", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G181367A", - "A196604-" - ] - }, - "labels": { - "clade": "B.1.9" - } - }, - "children": [ - { - "name": "Monkeypox/PT0043/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0043/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON843175" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-30" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "Monkeypox/PT0311/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0311/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP414345" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-06" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "DC_INS_MPX_0718_L", - "node_attrs": { - "div": 2, - "author": { - "author": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M.", - "value": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M." - }, - "strain_original": { - "value": "DC_INS_MPX_0718_L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP693652" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-16" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-596T", - "G134122T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "NODE_0000065", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C101868T", - "C103427T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG121": [ - "P27S" - ] - }, - "labels": { - "aa": "OPG121: P27S" - } - }, - "children": [ - { - "name": "NY-NYCPHL-000330", - "node_attrs": { - "div": 5, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000330" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468869" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-08" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G107496A", - "G173727A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T" - ] - } - } - }, - { - "name": "NODE_0000066", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G61329A" - ] - } - }, - "children": [ - { - "name": "MPXV_USA_2022_NJ0005", - "node_attrs": { - "div": 4, - "author": { - "author": "Gigante,C.M., Acheampong,E., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Morrison,S.S., Seabolt,M.H., Weigand,M.R., Knipe,K., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., McDermott,D., Li,Y.", - "value": "Gigante,C.M., Acheampong,E., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Morrison,S.S., Seabolt,M.H., Weigand,M.R., Knipe,K., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., McDermott,D., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_NJ0005" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP687938" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NY-NYCPHL-000422", - "node_attrs": { - "div": 5, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000422" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ419012" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-07" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T39394-", - "A39395-", - "T39396-", - "A49374G", - "T50371-", - "C50372-", - "T50373-", - "C50374-", - "T50375-", - "A50376-", - "C50377-", - "C50378-", - "C50379-", - "T50380-", - "A50381-", - "A50382-", - "A50383-", - "C50384-", - "T50385-", - "T50386-", - "T50387-", - "A50388-", - "A50389-", - "C50390-", - "A50391-", - "A50392-", - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T" - ], - "OPG057": [ - "N267X", - "R268X", - "*373X" - ], - "OPG068": [ - "N392D" - ], - "OPG069": [ - "L129X", - "S130-", - "T131-", - "L132-", - "N133-", - "F134-", - "N135-", - "N136X", - "*167X" - ] - }, - "labels": { - "aa": "OPG057: N267X, R268X, *373X; OPG068: N392D; OPG069: L129X, S130-, T131-, L132-, N133-, F134-, N135-, N136X, *167X" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000067", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G176823A" - ], - "OPG205": [ - "E390K" - ] - }, - "labels": { - "aa": "OPG205: E390K" - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-3336/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3336/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880538" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-01" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C32627T" - ] - } - } - }, - { - "name": "Monkeypox/PT0236/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0236/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP324544" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-22" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A11326-", - "T11327-", - "C11328-", - "T11329-", - "A11330-", - "C11331-", - "G11332-", - "A11333-", - "T11334-", - "A11335-", - "T11336-", - "T11337-", - "A11338-", - "G11339-", - "A11340-", - "T11341-", - "A11342-", - "C11343-", - "T11344-", - "T11345-", - "C11346-", - "A11347-", - "C11348-", - "T11349-", - "C11350-", - "A11351-", - "A11352-", - "T11353-", - "G11354-", - "A11355-", - "A11356-", - "T11357-", - "C11358-", - "A11359-", - "A11360-", - "T11361-", - "C11362-", - "A11363-", - "C11364-", - "A11365-", - "C11366-", - "A11367-", - "A11368-", - "T11369-", - "C11370-", - "T11371-", - "A11372-", - "A11373-", - "T11374-", - "G11375-", - "T11376-", - "A11377-", - "G11378-", - "G11379-", - "T11380-", - "T11381-", - "T11382-", - "A11383-", - "T11384-", - "G11385-", - "A11386-", - "C11387-", - "A11388-", - "T11389-", - "A11390-", - "A11391-", - "T11392-", - "A11393-", - "G11394-", - "C11395-", - "A11396-", - "T11397-", - "T11398-", - "T11399-", - "T11400-", - "C11401-", - "A11402-", - "G11403-", - "C11404-", - "A11405-", - "G11406-", - "T11407-", - "T11408-", - "C11409-", - "A11410-", - "A11411-", - "T11412-", - "G11413-", - "T11414-", - "T11415-", - "T11416-", - "C11417-", - "T11418-", - "A11419-", - "G11420-", - "A11421-", - "T11422-", - "T11423-", - "C11424-", - "G11425-", - "T11426-", - "T11427-", - "G11428-", - "A11429-", - "T11430-", - "G11431-", - "G11432-", - "C11433-", - "A11434-", - "A11435-", - "T11436-", - "G11437-", - "G11438-", - "T11439-", - "T11440-", - "A11441-", - "T11442-", - "A11443-", - "C11444-", - "A11445-", - "T11446-", - "G11447-", - "T11448-", - "A11449-", - "T11450-", - "A11451-", - "T11452-", - "C11453-", - "C11454-", - "G11455-", - "T11456-", - "T11457-", - "A11458-", - "T11459-", - "T11460-", - "T11461-", - "G11462-", - "A11463-", - "T11464-", - "C11465-", - "T11466-", - "A11467-", - "A11468-", - "T11469-", - "G11470-", - "T11471-", - "T11472-", - "G11473-", - "A11474-", - "C11475-", - "A11476-", - "T11477-", - "C11478-", - "T11479-", - "G11480-", - "A11481-", - "A11482-", - "C11483-", - "C11484-", - "G11485-", - "G11486-", - "A11487-", - "T11488-", - "T11489-", - "C11490-", - "T11491-", - "A11492-", - "G11493-", - "C11494-", - "A11495-", - "G11496-", - "T11497-", - "A11498-", - "A11499-", - "A11500-", - "G11501-", - "A11502-", - "T11503-", - "A11504-", - "C11505-", - "T11506-", - "A11507-", - "G11508-", - "A11509-", - "G11510-", - "A11511-", - "T11512-", - "T11513-", - "G11514-", - "T11515-", - "T11516-", - "T11517-", - "A11518-", - "T11519-", - "T11520-", - "A11521-", - "T11522-", - "A11523-", - "T11524-", - "C11525-", - "T11526-", - "A11527-", - "A11528-", - "C11529-", - "A11530-", - "G11531-", - "C11532-", - "C11533-", - "T11534-", - "T11535-", - "G11536-", - "T11537-", - "G11538-", - "A11539-", - "A11540-", - "G11541-", - "A11542-", - "A11543-", - "G11544-", - "T11545-", - "G11546-", - "T11547-", - "T11548-", - "T11549-", - "C11550-", - "T11551-", - "C11552-", - "C11553-", - "T11554-", - "C11555-", - "G11556-", - "T11557-", - "T11558-", - "T11559-", - "G11560-", - "T11561-", - "C11562-", - "A11563-", - "A11564-", - "T11565-", - "C11566-", - "A11567-", - "T11568-", - "G11569-", - "T11570-", - "T11571-", - "A11572-", - "A11573-", - "T11574-", - "G11575-", - "T11576-", - "C11577-", - "T11578-", - "T11579-", - "T11580-", - "A11581-", - "A11582-", - "G11583-", - "A11584-", - "T11585-", - "A11586-", - "A11587-", - "G11588-", - "G11589-", - "T11590-", - "A11591-", - "G11592-", - "A11593-", - "C11594-", - "A11595-", - "A11596-", - "A11597-", - "T11598-", - "G11599-", - "T11600-", - "T11601-", - "T11602-", - "A11603-", - "T11604-", - "A11605-", - "G11606-", - "T11607-", - "A11608-", - "C11609-", - "T11610-", - "A11611-", - "A11612-", - "G11613-", - "A11614-", - "A11615-", - "T11616-", - "T11617-", - "G11618-", - "G11619-", - "G11620-", - "C11621-", - "A11622-", - "A11623-", - "A11624-", - "C11625-", - "A11626-", - "T11627-", - "A11628-", - "A11629-", - "G11630-", - "A11631-", - "C11632-", - "A11633-", - "T11634-", - "G11635-", - "T11636-", - "C11637-", - "A11638-", - "C11639-", - "A11640-", - "A11641-", - "A11642-", - "G11643-", - "A11644-", - "C11645-", - "C11646-", - "C11647-", - "T11648-", - "T11649-", - "T11650-", - "T11651-", - "T11652-", - "G11653-", - "T11654-", - "A11655-", - "T11656-", - "G11657-", - "T11658-", - "A11659-", - "T11660-", - "A11661-", - "A11662-", - "G11663-", - "T11664-", - "G11665-", - "T11666-", - "A11667-", - "G11668-", - "A11669-", - "A11670-", - "A11671-", - "T11672-", - "T11673-", - "A11674-", - "T11675-", - "A11676-", - "A11677-", - "C11678-", - "A11679-", - "T11680-", - "C11681-", - "C11682-", - "A11683-", - "T11684-", - "A11685-", - "G11686-", - "T11687-", - "T11688-", - "G11689-", - "G11690-", - "A11691-", - "T11692-", - "T11693-", - "C11694-", - "A11695-", - "C11696-", - "A11697-", - "T11698-", - "A11699-", - "G11700-", - "G11701-", - "T11702-", - "G11703-", - "T11704-", - "C11705-", - "C11706-", - "A11707-", - "A11708-", - "T11709-", - "C11710-", - "G11711-", - "G11712-", - "G11713-", - "A11714-", - "T11715-", - "C11716-", - "T11717-", - "C11718-", - "T11719-", - "C11720-", - "C11721-", - "A11722-", - "T11723-", - "C11724-", - "A11725-", - "T11726-", - "C11727-", - "G11728-", - "A11729-", - "G11730-", - "A11731-", - "T11732-", - "G11733-", - "A11734-", - "T11735-", - "T11736-", - "G11737-", - "A11738-", - "C11739-", - "G11740-", - "G11741-", - "C11742-", - "A11743-", - "T11744-", - "C11745-", - "T11746-", - "C11747-", - "C11748-", - "C11749-", - "C11750-", - "C11751-", - "T11752-", - "T11753-", - "C11754-", - "C11755-", - "T11756-", - "T11757-", - "T11758-", - "T11759-", - "T11760-", - "T11761-", - "A11762-", - "G11763-", - "T11764-", - "A11765-", - "G11766-", - "A11767-", - "T11768-", - "A11769-", - "T11770-", - "T11771-", - "T11772-", - "C11773-", - "A11774-", - "T11775-", - "C11776-", - "G11777-", - "T11778-", - "G11779-", - "T11780-", - "A11781-", - "A11782-", - "G11783-", - "A11784-", - "A11785-", - "T11786-", - "C11787-", - "A11788-", - "A11789-", - "T11790-", - "A11791-", - "T11792-", - "T11793-", - "A11794-", - "A11795-", - "T11796-", - "A11797-", - "T11798-", - "T11799-", - "T11800-", - "C11801-", - "T11802-", - "A11803-", - "A11804-", - "A11805-", - "G11806-", - "T11807-", - "A11808-", - "T11809-", - "C11810-", - "T11811-", - "G11812-", - "T11813-", - "G11814-", - "T11815-", - "A11816-", - "T11817-", - "A11818-", - "G11819-", - "C11820-", - "C11821-", - "T11822-", - "C11823-", - "T11824-", - "T11825-", - "T11826-", - "A11827-", - "T11828-", - "T11829-", - "T11830-", - "A11831-", - "C11832-", - "C11833-", - "A11834-", - "C11835-", - "A11836-", - "G11837-", - "C11838-", - "T11839-", - "C11840-", - "C11841-", - "A11842-", - "T11843-", - "A11844-", - "T11845-", - "T11846-", - "C11847-", - "C11848-", - "A11849-", - "A11850-", - "C11851-", - "A11852-", - "T11853-", - "G11854-", - "C11855-", - "A11856-", - "T11857-", - "T11858-", - "C11859-", - "C11860-", - "A11861-", - "C11862-", - "T11863-", - "A11864-", - "G11865-", - "A11866-", - "G11867-", - "G11868-", - "G11869-", - "A11870-", - "T11871-", - "A11872-", - "T11873-", - "C11874-", - "G11875-", - "A11876-", - "T11877-", - "A11878-", - "T11879-", - "C11880-", - "G11881-", - "C11882-", - "C11883-", - "G11884-", - "A11885-", - "A11886-", - "T11887-", - "G11888-", - "T11889-", - "C11890-", - "A11891-", - "T11892-", - "A11893-", - "T11894-", - "A11895-", - "C11896-", - "T11897-", - "C11898-", - "A11899-", - "A11900-", - "T11901-", - "T11902-", - "A11903-", - "G11904-", - "T11905-", - "A11906-", - "T11907-", - "A11908-", - "T11909-", - "G11910-", - "T11911-", - "T11912-", - "G11913-", - "G11914-", - "A11915-", - "G11916-", - "G11917-", - "A11918-", - "C11919-", - "A11920-", - "T11921-", - "C11922-", - "C11923-", - "G11924-", - "A11925-", - "G11926-", - "T11927-", - "T11928-", - "C11929-", - "A11930-", - "T11931-", - "T11932-", - "G11933-", - "T11934-", - "T11935-", - "T11936-", - "T11937-", - "C11938-", - "A11939-", - "A11940-", - "T11941-", - "A11942-", - "T11943-", - "C11944-", - "A11945-", - "A11946-", - "A11947-", - "G11948-", - "A11949-", - "G11950-", - "A11951-", - "T11952-", - "G11953-", - "G11954-", - "T11955-", - "T11956-", - "T11957-", - "C11958-", - "C11959-", - "T11960-", - "T11961-", - "A11962-", - "T11963-", - "C11964-", - "A11965-", - "T11966-", - "T11967-", - "T11968-", - "C11969-", - "T11970-", - "C11971-", - "C11972-", - "A11973-", - "T11974-", - "A11975-", - "G11976-", - "T11977-", - "G11978-", - "G11979-", - "T11980-", - "A11981-", - "C11982-", - "A11983-", - "A11984-", - "T11985-", - "A11986-", - "C11987-", - "T11988-", - "A11989-", - "C11990-", - "A11991-", - "C11992-", - "A11993-", - "T11994-", - "T11995-", - "A11996-", - "T11997-", - "T11998-", - "C11999-", - "C12000-", - "G12001-", - "T12002-", - "A12003-", - "C12004-", - "G12005-", - "G12006-", - "C12007-", - "T12008-", - "T12009-", - "T12010-", - "C12011-", - "C12012-", - "A12013-", - "T12014-", - "T12015-", - "C12016-", - "T12017-", - "C12018-", - "C12019-", - "A12020-", - "A12021-", - "A12022-", - "A12023-", - "A12024-", - "C12025-", - "A12026-", - "A12027-", - "T12028-", - "T12029-", - "T12030-", - "T12031-", - "A12032-", - "C12033-", - "C12034-", - "A12035-", - "A12036-", - "A12037-", - "T12038-", - "C12039-", - "T12040-", - "A12041-", - "A12042-", - "A12043-", - "T12044-", - "C12045-", - "T12046-", - "A12047-", - "C12048-", - "A12049-", - "T12050-", - "C12051-", - "T12052-", - "T12053-", - "T12054-", - "A12055-", - "T12056-", - "T12057-", - "G12058-", - "T12059-", - "A12060-", - "T12061-", - "C12062-", - "T12063-", - "A12064-", - "T12065-", - "A12066-", - "A12067-", - "T12068-", - "C12069-", - "A12070-", - "C12071-", - "T12072-", - "A12073-", - "T12074-", - "T12075-", - "T12076-", - "A12077-", - "G12078-", - "A12079-", - "T12080-", - "A12081-", - "A12082-", - "T12083-", - "C12084-", - "A12085-", - "G12086-", - "C12087-", - "C12088-", - "A12089-", - "T12090-", - "A12091-", - "A12092-", - "T12093-", - "T12094-", - "C12095-", - "C12096-", - "T12097-", - "C12098-", - "G12099-", - "A12100-", - "G12101-", - "T12102-", - "G12103-", - "C12104-", - "A12105-", - "A12106-", - "C12107-", - "A12108-", - "T12109-", - "G12110-", - "T12111-", - "T12112-", - "A12113-", - "G12114-", - "A12115-", - "T12116-", - "C12117-", - "G12118-", - "T12119-", - "C12120-", - "T12121-", - "A12122-", - "T12123-", - "A12124-", - "T12125-", - "A12126-", - "T12127-", - "G12128-", - "A12129-", - "A12130-", - "T12131-", - "A12132-", - "A12133-", - "G12134-", - "C12135-", - "C12136-", - "G12137-", - "T12138-", - "G12139-", - "T12140-", - "T12141-", - "A12142-", - "T12143-", - "C12144-", - "T12145-", - "A12146-", - "T12147-", - "T12148-", - "C12149-", - "C12150-", - "T12151-", - "T12152-", - "T12153-", - "C12154-", - "A12155-", - "T12156-", - "T12157-", - "A12158-", - "A12159-", - "C12160-", - "A12161-", - "A12162-", - "T12163-", - "T12164-", - "T12165-", - "A12166-", - "A12167-", - "C12168-", - "G12169-", - "A12170-", - "T12171-", - "G12172-", - "T12173-", - "C12174-", - "T12175-", - "A12176-", - "T12177-", - "A12178-", - "T12179-", - "C12180-", - "T12181-", - "A12182-", - "T12183-", - "A12184-", - "T12185-", - "G12186-", - "A12187-", - "G12188-", - "A12189-", - "T12190-", - "G12191-", - "A12192-", - "C12193-", - "T12194-", - "T12195-", - "A12196-", - "A12197-", - "T12198-", - "A12199-", - "T12200-", - "A12201-", - "A12202-", - "T12203-", - "A12204-", - "T12205-", - "T12206-", - "G12207-", - "A12208-", - "A12209-", - "G12210-", - "A12211-", - "G12212-", - "C12213-", - "T12214-", - "G12215-", - "T12216-", - "A12217-", - "C12218-", - "A12219-", - "A12220-", - "T12221-", - "A12222-", - "G12223-", - "T12224-", - "T12225-", - "T12226-", - "T12227-", - "T12228-", - "A12229-", - "T12230-", - "C12231-", - "T12232-", - "A12233-", - "T12234-", - "A12235-", - "G12236-", - "A12237-", - "A12238-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C156081T" - ], - "OPG023": [ - "S221X", - "S222-", - "I223-", - "D224-", - "K225-", - "N226-", - "Y227-", - "C228-", - "T229-", - "A230-", - "L231-", - "Q232-", - "Y233-", - "Y234-", - "I235-", - "K236-", - "S237-", - "S238-", - "H239-", - "I240-", - "D241-", - "I242-", - "D243-", - "I244-", - "V245-", - "K246-", - "L247-", - "L248-", - "M249-", - "K250-", - "G251-", - "I252-", - "D253-", - "N254-", - "T255-", - "A256-", - "Y257-", - "S258-", - "Y259-", - "I260-", - "D261-", - "D262-", - "L263-", - "T264-", - "C265-", - "C266-", - "T267-", - "R268-", - "G269-", - "I270-", - "M271-", - "A272-", - "D273-", - "Y274-", - "L275-", - "N276-", - "S277-", - "D278-", - "Y279-", - "R280-", - "Y281-", - "N282-", - "K283-", - "D284-", - "V285-", - "D286-", - "L287-", - "D288-", - "L289-", - "V290-", - "K291-", - "L292-", - "F293-", - "L294-", - "E295-", - "N296-", - "G297-", - "K298-", - "P299-", - "Y300-", - "G301-", - "I302-", - "M303-", - "C304-", - "S305-", - "I306-", - "V307-", - "P308-", - "L309-", - "W310-", - "R311-", - "N312-", - "D313-", - "K314-", - "E315-", - "T316-", - "I317-", - "S318-", - "L319-", - "I320-", - "L321-", - "K322-", - "T323-", - "M324-", - "N325-", - "S326-", - "D327-", - "V328-", - "L329-", - "Q330-", - "H331-", - "I332-", - "L333-", - "I334-", - "E335-", - "Y336-", - "M337-", - "T338-", - "F339-", - "G340-", - "D341-", - "I342-", - "D343-", - "I344-", - "P345-", - "L346-", - "V347-", - "E348-", - "C349-", - "M350-", - "L351-", - "E352-", - "Y353-", - "G354-", - "A355-", - "V356-", - "V357-", - "N358-", - "K359-", - "E360-", - "A361-", - "I362-", - "H363-", - "R364-", - "Y365-", - "F366-", - "R367-", - "N368-", - "I369-", - "N370-", - "I371-", - "D372-", - "S373-", - "Y374-", - "T375-", - "M376-", - "K377-", - "Y378-", - "L379-", - "L380-", - "K381-", - "K382-", - "E383-", - "G384-", - "G385-", - "D386-", - "A387-", - "V388-", - "N389-", - "H390-", - "L391-", - "D392-", - "D393-", - "G394-", - "E395-", - "I396-", - "P397-", - "I398-", - "G399-", - "H400-", - "L401-", - "C402-", - "E403-", - "S404-", - "N405-", - "Y406-", - "G407-", - "C408-", - "Y409-", - "N410-", - "F411-", - "Y412-", - "T413-", - "Y414-", - "T415-", - "Y416-", - "K417-", - "K418-", - "G419-", - "L420-", - "C421-", - "D422-", - "M423-", - "S424-", - "Y425-", - "V426-", - "C427-", - "P428-", - "I429-", - "L430-", - "S431-", - "T432-", - "I433-", - "N434-", - "I435-", - "C436-", - "L437-", - "P438-", - "Y439-", - "L440-", - "K441-", - "D442-", - "I443-", - "N444-", - "M445-", - "I446-", - "D447-", - "K448-", - "R449-", - "G450-", - "E451-", - "T452-", - "L453-", - "L454-", - "H455-", - "K456-", - "A457-", - "V458-", - "R459-", - "Y460-", - "N461-", - "K462-", - "Q463-", - "S464-", - "L465-", - "V466-", - "S467-", - "L468-", - "L469-", - "L470-", - "E471-", - "S472-", - "G473-", - "S474-", - "D475-", - "V476-", - "N477-", - "I478-", - "R479-", - "S480-", - "N481-", - "N482-", - "G483-", - "Y484-", - "T485-", - "C486-", - "I487-", - "T488-", - "I489-", - "A490-", - "I491-", - "N492-", - "E493-", - "S494-", - "R495-", - "N496-", - "I497-", - "E498-", - "L499-", - "L500-", - "K501-", - "M502-", - "L503-", - "L504-", - "C505-", - "H506-", - "K507-", - "P508-", - "T509-", - "L510-", - "D511-", - "C512-", - "V513-", - "I514-", - "D515-", - "S516-", - "L517-", - "S518-", - "E519-", - "V520-", - "S521-", - "N522-", - "I523-", - "V524-", - "D525-", - "*661X" - ] - }, - "labels": { - "aa": "OPG023: S221X, S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-, *661X" - } - } - }, - { - "name": "NODE_0000068", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-596T", - "A11326-", - "T11327-", - "C11328-", - "T11329-", - "A11330-", - "C11331-", - "G11332-", - "A11333-", - "T11334-", - "A11335-", - "T11336-", - "T11337-", - "A11338-", - "G11339-", - "A11340-", - "T11341-", - "A11342-", - "C11343-", - "T11344-", - "T11345-", - "C11346-", - "A11347-", - "C11348-", - "T11349-", - "C11350-", - "A11351-", - "A11352-", - "T11353-", - "G11354-", - "A11355-", - "A11356-", - "T11357-", - "C11358-", - "A11359-", - "A11360-", - "T11361-", - "C11362-", - "A11363-", - "C11364-", - "A11365-", - "C11366-", - "A11367-", - "A11368-", - "T11369-", - "C11370-", - "T11371-", - "A11372-", - "A11373-", - "T11374-", - "G11375-", - "T11376-", - "A11377-", - "G11378-", - "G11379-", - "T11380-", - "T11381-", - "T11382-", - "A11383-", - "T11384-", - "G11385-", - "A11386-", - "C11387-", - "A11388-", - "T11389-", - "A11390-", - "A11391-", - "T11392-", - "A11393-", - "G11394-", - "C11395-", - "A11396-", - "T11397-", - "T11398-", - "T11399-", - "T11400-", - "C11401-", - "A11402-", - "G11403-", - "C11404-", - "A11405-", - "G11406-", - "T11407-", - "T11408-", - "C11409-", - "A11410-", - "A11411-", - "T11412-", - "G11413-", - "T11414-", - "T11415-", - "T11416-", - "C11417-", - "T11418-", - "A11419-", - "G11420-", - "A11421-", - "T11422-", - "T11423-", - "C11424-", - "G11425-", - "T11426-", - "T11427-", - "G11428-", - "A11429-", - "T11430-", - "G11431-", - "G11432-", - "C11433-", - "A11434-", - "A11435-", - "T11436-", - "G11437-", - "G11438-", - "T11439-", - "T11440-", - "A11441-", - "T11442-", - "A11443-", - "C11444-", - "A11445-", - "T11446-", - "G11447-", - "T11448-", - "A11449-", - "T11450-", - "A11451-", - "T11452-", - "C11453-", - "C11454-", - "G11455-", - "T11456-", - "T11457-", - "A11458-", - "T11459-", - "T11460-", - "T11461-", - "G11462-", - "A11463-", - "T11464-", - "C11465-", - "T11466-", - "A11467-", - "A11468-", - "T11469-", - "G11470-", - "T11471-", - "T11472-", - "G11473-", - "A11474-", - "C11475-", - "A11476-", - "T11477-", - "C11478-", - "T11479-", - "G11480-", - "A11481-", - "A11482-", - "C11483-", - "C11484-", - "G11485-", - "G11486-", - "A11487-", - "T11488-", - "T11489-", - "C11490-", - "T11491-", - "A11492-", - "G11493-", - "C11494-", - "A11495-", - "G11496-", - "T11497-", - "A11498-", - "A11499-", - "A11500-", - "G11501-", - "A11502-", - "T11503-", - "A11504-", - "C11505-", - "T11506-", - "A11507-", - "G11508-", - "A11509-", - "G11510-", - "A11511-", - "T11512-", - "T11513-", - "G11514-", - "T11515-", - "T11516-", - "T11517-", - "A11518-", - "T11519-", - "T11520-", - "A11521-", - "T11522-", - "A11523-", - "T11524-", - "C11525-", - "T11526-", - "A11527-", - "A11528-", - "C11529-", - "A11530-", - "G11531-", - "C11532-", - "C11533-", - "T11534-", - "T11535-", - "G11536-", - "T11537-", - "G11538-", - "A11539-", - "A11540-", - "G11541-", - "A11542-", - "A11543-", - "G11544-", - "T11545-", - "G11546-", - "T11547-", - "T11548-", - "T11549-", - "C11550-", - "T11551-", - "C11552-", - "C11553-", - "T11554-", - "C11555-", - "G11556-", - "T11557-", - "T11558-", - "T11559-", - "G11560-", - "T11561-", - "C11562-", - "A11563-", - "A11564-", - "T11565-", - "C11566-", - "A11567-", - "T11568-", - "G11569-", - "T11570-", - "T11571-", - "A11572-", - "A11573-", - "T11574-", - "G11575-", - "T11576-", - "C11577-", - "T11578-", - "T11579-", - "T11580-", - "A11581-", - "A11582-", - "G11583-", - "A11584-", - "T11585-", - "A11586-", - "A11587-", - "G11588-", - "G11589-", - "T11590-", - "A11591-", - "G11592-", - "A11593-", - "C11594-", - "A11595-", - "A11596-", - "A11597-", - "T11598-", - "G11599-", - "T11600-", - "T11601-", - "T11602-", - "A11603-", - "T11604-", - "A11605-", - "G11606-", - "T11607-", - "A11608-", - "C11609-", - "T11610-", - "A11611-", - "A11612-", - "G11613-", - "A11614-", - "A11615-", - "T11616-", - "T11617-", - "G11618-", - "G11619-", - "G11620-", - "C11621-", - "A11622-", - "A11623-", - "A11624-", - "C11625-", - "A11626-", - "T11627-", - "A11628-", - "A11629-", - "G11630-", - "A11631-", - "C11632-", - "A11633-", - "T11634-", - "G11635-", - "T11636-", - "C11637-", - "A11638-", - "C11639-", - "A11640-", - "A11641-", - "A11642-", - "G11643-", - "A11644-", - "C11645-", - "C11646-", - "C11647-", - "T11648-", - "T11649-", - "T11650-", - "T11651-", - "T11652-", - "G11653-", - "T11654-", - "A11655-", - "T11656-", - "G11657-", - "T11658-", - "A11659-", - "T11660-", - "A11661-", - "A11662-", - "G11663-", - "T11664-", - "G11665-", - "T11666-", - "A11667-", - "G11668-", - "A11669-", - "A11670-", - "A11671-", - "T11672-", - "T11673-", - "A11674-", - "T11675-", - "A11676-", - "A11677-", - "C11678-", - "A11679-", - "T11680-", - "C11681-", - "C11682-", - "A11683-", - "T11684-", - "A11685-", - "G11686-", - "T11687-", - "T11688-", - "G11689-", - "G11690-", - "A11691-", - "T11692-", - "T11693-", - "C11694-", - "A11695-", - "C11696-", - "A11697-", - "T11698-", - "A11699-", - "G11700-", - "G11701-", - "T11702-", - "G11703-", - "T11704-", - "C11705-", - "C11706-", - "A11707-", - "A11708-", - "T11709-", - "C11710-", - "G11711-", - "G11712-", - "G11713-", - "A11714-", - "T11715-", - "C11716-", - "T11717-", - "C11718-", - "T11719-", - "C11720-", - "C11721-", - "A11722-", - "T11723-", - "C11724-", - "A11725-", - "T11726-", - "C11727-", - "G11728-", - "A11729-", - "G11730-", - "A11731-", - "T11732-", - "G11733-", - "A11734-", - "T11735-", - "T11736-", - "G11737-", - "A11738-", - "C11739-", - "G11740-", - "G11741-", - "C11742-", - "A11743-", - "T11744-", - "C11745-", - "T11746-", - "C11747-", - "C11748-", - "C11749-", - "C11750-", - "C11751-", - "T11752-", - "T11753-", - "C11754-", - "C11755-", - "T11756-", - "T11757-", - "T11758-", - "T11759-", - "T11760-", - "T11761-", - "A11762-", - "G11763-", - "T11764-", - "A11765-", - "G11766-", - "A11767-", - "T11768-", - "A11769-", - "T11770-", - "T11771-", - "T11772-", - "C11773-", - "A11774-", - "T11775-", - "C11776-", - "G11777-", - "T11778-", - "G11779-", - "T11780-", - "A11781-", - "A11782-", - "G11783-", - "A11784-", - "A11785-", - "T11786-", - "C11787-", - "A11788-", - "A11789-", - "T11790-", - "A11791-", - "T11792-", - "T11793-", - "A11794-", - "A11795-", - "T11796-", - "A11797-", - "T11798-", - "T11799-", - "T11800-", - "C11801-", - "T11802-", - "A11803-", - "A11804-", - "A11805-", - "G11806-", - "T11807-", - "A11808-", - "T11809-", - "C11810-", - "T11811-", - "G11812-", - "T11813-", - "G11814-", - "T11815-", - "A11816-", - "T11817-", - "A11818-", - "G11819-", - "C11820-", - "C11821-", - "T11822-", - "C11823-", - "T11824-", - "T11825-", - "T11826-", - "A11827-", - "T11828-", - "T11829-", - "T11830-", - "A11831-", - "C11832-", - "C11833-", - "A11834-", - "C11835-", - "A11836-", - "G11837-", - "C11838-", - "T11839-", - "C11840-", - "C11841-", - "A11842-", - "T11843-", - "A11844-", - "T11845-", - "T11846-", - "C11847-", - "C11848-", - "A11849-", - "A11850-", - "C11851-", - "A11852-", - "T11853-", - "G11854-", - "C11855-", - "A11856-", - "T11857-", - "T11858-", - "C11859-", - "C11860-", - "A11861-", - "C11862-", - "T11863-", - "A11864-", - "G11865-", - "A11866-", - "G11867-", - "G11868-", - "G11869-", - "A11870-", - "T11871-", - "A11872-", - "T11873-", - "C11874-", - "G11875-", - "A11876-", - "T11877-", - "A11878-", - "T11879-", - "C11880-", - "G11881-", - "C11882-", - "C11883-", - "G11884-", - "A11885-", - "A11886-", - "T11887-", - "G11888-", - "T11889-", - "C11890-", - "A11891-", - "T11892-", - "A11893-", - "T11894-", - "A11895-", - "C11896-", - "T11897-", - "C11898-", - "A11899-", - "A11900-", - "T11901-", - "T11902-", - "A11903-", - "G11904-", - "T11905-", - "A11906-", - "T11907-", - "A11908-", - "T11909-", - "G11910-", - "T11911-", - "T11912-", - "G11913-", - "G11914-", - "A11915-", - "G11916-", - "G11917-", - "A11918-", - "C11919-", - "A11920-", - "T11921-", - "C11922-", - "C11923-", - "G11924-", - "A11925-", - "G11926-", - "T11927-", - "T11928-", - "C11929-", - "A11930-", - "T11931-", - "T11932-", - "G11933-", - "T11934-", - "T11935-", - "T11936-", - "T11937-", - "C11938-", - "A11939-", - "A11940-", - "T11941-", - "A11942-", - "T11943-", - "C11944-", - "A11945-", - "A11946-", - "A11947-", - "G11948-", - "A11949-", - "G11950-", - "A11951-", - "T11952-", - "G11953-", - "G11954-", - "T11955-", - "T11956-", - "T11957-", - "C11958-", - "C11959-", - "T11960-", - "T11961-", - "A11962-", - "T11963-", - "C11964-", - "A11965-", - "T11966-", - "T11967-", - "T11968-", - "C11969-", - "T11970-", - "C11971-", - "C11972-", - "A11973-", - "T11974-", - "A11975-", - "G11976-", - "T11977-", - "G11978-", - "G11979-", - "T11980-", - "A11981-", - "C11982-", - "A11983-", - "A11984-", - "T11985-", - "A11986-", - "C11987-", - "T11988-", - "A11989-", - "C11990-", - "A11991-", - "C11992-", - "A11993-", - "T11994-", - "T11995-", - "A11996-", - "T11997-", - "T11998-", - "C11999-", - "C12000-", - "G12001-", - "T12002-", - "A12003-", - "C12004-", - "G12005-", - "G12006-", - "C12007-", - "T12008-", - "T12009-", - "T12010-", - "C12011-", - "C12012-", - "A12013-", - "T12014-", - "T12015-", - "C12016-", - "T12017-", - "C12018-", - "C12019-", - "A12020-", - "A12021-", - "A12022-", - "A12023-", - "A12024-", - "C12025-", - "A12026-", - "A12027-", - "T12028-", - "T12029-", - "T12030-", - "T12031-", - "A12032-", - "C12033-", - "C12034-", - "A12035-", - "A12036-", - "A12037-", - "T12038-", - "C12039-", - "T12040-", - "A12041-", - "A12042-", - "A12043-", - "T12044-", - "C12045-", - "T12046-", - "A12047-", - "C12048-", - "A12049-", - "T12050-", - "C12051-", - "T12052-", - "T12053-", - "T12054-", - "A12055-", - "T12056-", - "T12057-", - "G12058-", - "T12059-", - "A12060-", - "T12061-", - "C12062-", - "T12063-", - "A12064-", - "T12065-", - "A12066-", - "A12067-", - "T12068-", - "C12069-", - "A12070-", - "C12071-", - "T12072-", - "A12073-", - "T12074-", - "T12075-", - "T12076-", - "A12077-", - "G12078-", - "A12079-", - "T12080-", - "A12081-", - "A12082-", - "T12083-", - "C12084-", - "A12085-", - "G12086-", - "C12087-", - "C12088-", - "A12089-", - "T12090-", - "A12091-", - "A12092-", - "T12093-", - "T12094-", - "C12095-", - "C12096-", - "T12097-", - "C12098-", - "G12099-", - "A12100-", - "G12101-", - "T12102-", - "G12103-", - "C12104-", - "A12105-", - "A12106-", - "C12107-", - "A12108-", - "T12109-", - "G12110-", - "T12111-", - "T12112-", - "A12113-", - "G12114-", - "A12115-", - "T12116-", - "C12117-", - "G12118-", - "T12119-", - "C12120-", - "T12121-", - "A12122-", - "T12123-", - "A12124-", - "T12125-", - "A12126-", - "T12127-", - "G12128-", - "A12129-", - "A12130-", - "T12131-", - "A12132-", - "A12133-", - "G12134-", - "C12135-", - "C12136-", - "G12137-", - "T12138-", - "G12139-", - "T12140-", - "T12141-", - "A12142-", - "T12143-", - "C12144-", - "T12145-", - "A12146-", - "T12147-", - "T12148-", - "C12149-", - "C12150-", - "T12151-", - "T12152-", - "T12153-", - "C12154-", - "A12155-", - "T12156-", - "T12157-", - "A12158-", - "A12159-", - "C12160-", - "A12161-", - "A12162-", - "T12163-", - "T12164-", - "T12165-", - "A12166-", - "A12167-", - "C12168-", - "G12169-", - "A12170-", - "T12171-", - "G12172-", - "T12173-", - "C12174-", - "T12175-", - "A12176-", - "T12177-", - "A12178-", - "T12179-", - "C12180-", - "T12181-", - "A12182-", - "T12183-", - "A12184-", - "T12185-", - "G12186-", - "A12187-", - "G12188-", - "A12189-", - "T12190-", - "G12191-", - "A12192-", - "C12193-", - "T12194-", - "T12195-", - "A12196-", - "A12197-", - "T12198-", - "A12199-", - "T12200-", - "A12201-", - "A12202-", - "T12203-", - "A12204-", - "T12205-", - "T12206-", - "G12207-", - "A12208-", - "A12209-", - "G12210-", - "A12211-", - "G12212-", - "C12213-", - "T12214-", - "G12215-", - "T12216-", - "A12217-", - "C12218-", - "A12219-", - "A12220-", - "T12221-", - "A12222-", - "G12223-", - "T12224-", - "T12225-", - "T12226-", - "T12227-", - "T12228-", - "A12229-", - "T12230-", - "C12231-", - "T12232-", - "A12233-", - "T12234-", - "A12235-", - "G12236-", - "A12237-", - "A12238-", - "C57110T", - "-196604A" - ], - "OPG023": [ - "S221X", - "S222-", - "I223-", - "D224-", - "K225-", - "N226-", - "Y227-", - "C228-", - "T229-", - "A230-", - "L231-", - "Q232-", - "Y233-", - "Y234-", - "I235-", - "K236-", - "S237-", - "S238-", - "H239-", - "I240-", - "D241-", - "I242-", - "D243-", - "I244-", - "V245-", - "K246-", - "L247-", - "L248-", - "M249-", - "K250-", - "G251-", - "I252-", - "D253-", - "N254-", - "T255-", - "A256-", - "Y257-", - "S258-", - "Y259-", - "I260-", - "D261-", - "D262-", - "L263-", - "T264-", - "C265-", - "C266-", - "T267-", - "R268-", - "G269-", - "I270-", - "M271-", - "A272-", - "D273-", - "Y274-", - "L275-", - "N276-", - "S277-", - "D278-", - "Y279-", - "R280-", - "Y281-", - "N282-", - "K283-", - "D284-", - "V285-", - "D286-", - "L287-", - "D288-", - "L289-", - "V290-", - "K291-", - "L292-", - "F293-", - "L294-", - "E295-", - "N296-", - "G297-", - "K298-", - "P299-", - "Y300-", - "G301-", - "I302-", - "M303-", - "C304-", - "S305-", - "I306-", - "V307-", - "P308-", - "L309-", - "W310-", - "R311-", - "N312-", - "D313-", - "K314-", - "E315-", - "T316-", - "I317-", - "S318-", - "L319-", - "I320-", - "L321-", - "K322-", - "T323-", - "M324-", - "N325-", - "S326-", - "D327-", - "V328-", - "L329-", - "Q330-", - "H331-", - "I332-", - "L333-", - "I334-", - "E335-", - "Y336-", - "M337-", - "T338-", - "F339-", - "G340-", - "D341-", - "I342-", - "D343-", - "I344-", - "P345-", - "L346-", - "V347-", - "E348-", - "C349-", - "M350-", - "L351-", - "E352-", - "Y353-", - "G354-", - "A355-", - "V356-", - "V357-", - "N358-", - "K359-", - "E360-", - "A361-", - "I362-", - "H363-", - "R364-", - "Y365-", - "F366-", - "R367-", - "N368-", - "I369-", - "N370-", - "I371-", - "D372-", - "S373-", - "Y374-", - "T375-", - "M376-", - "K377-", - "Y378-", - "L379-", - "L380-", - "K381-", - "K382-", - "E383-", - "G384-", - "G385-", - "D386-", - "A387-", - "V388-", - "N389-", - "H390-", - "L391-", - "D392-", - "D393-", - "G394-", - "E395-", - "I396-", - "P397-", - "I398-", - "G399-", - "H400-", - "L401-", - "C402-", - "E403-", - "S404-", - "N405-", - "Y406-", - "G407-", - "C408-", - "Y409-", - "N410-", - "F411-", - "Y412-", - "T413-", - "Y414-", - "T415-", - "Y416-", - "K417-", - "K418-", - "G419-", - "L420-", - "C421-", - "D422-", - "M423-", - "S424-", - "Y425-", - "V426-", - "C427-", - "P428-", - "I429-", - "L430-", - "S431-", - "T432-", - "I433-", - "N434-", - "I435-", - "C436-", - "L437-", - "P438-", - "Y439-", - "L440-", - "K441-", - "D442-", - "I443-", - "N444-", - "M445-", - "I446-", - "D447-", - "K448-", - "R449-", - "G450-", - "E451-", - "T452-", - "L453-", - "L454-", - "H455-", - "K456-", - "A457-", - "V458-", - "R459-", - "Y460-", - "N461-", - "K462-", - "Q463-", - "S464-", - "L465-", - "V466-", - "S467-", - "L468-", - "L469-", - "L470-", - "E471-", - "S472-", - "G473-", - "S474-", - "D475-", - "V476-", - "N477-", - "I478-", - "R479-", - "S480-", - "N481-", - "N482-", - "G483-", - "Y484-", - "T485-", - "C486-", - "I487-", - "T488-", - "I489-", - "A490-", - "I491-", - "N492-", - "E493-", - "S494-", - "R495-", - "N496-", - "I497-", - "E498-", - "L499-", - "L500-", - "K501-", - "M502-", - "L503-", - "L504-", - "C505-", - "H506-", - "K507-", - "P508-", - "T509-", - "L510-", - "D511-", - "C512-", - "V513-", - "I514-", - "D515-", - "S516-", - "L517-", - "S518-", - "E519-", - "V520-", - "S521-", - "N522-", - "I523-", - "V524-", - "D525-", - "*661X" - ], - "OPG074": [ - "E6K" - ] - }, - "labels": { - "aa": "OPG023: S221X, S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-, *661X; OPG074: E6K" - } - }, - "children": [ - { - "name": "Monkeypox/PT0015/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J.D., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Carvalho,I.L., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J.D., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Carvalho,I.L., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0015/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON649714" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-20" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-11335A", - "-11336T", - "-11337T", - "-11338A", - "-11339G", - "-11340A", - "-11341T", - "-11342A", - "-11343C", - "-11344T", - "-11345T", - "-11346C", - "-11347A", - "-11348C", - "-11349T", - "-11350C", - "-11351A", - "-11352A", - "-11353T", - "-11354G", - "-11355A", - "-11356A", - "-11357T", - "-11358C", - "-11359A", - "-11360A", - "-11361T", - "-11362C", - "-11363A", - "-11364C", - "-11365A", - "-11366C", - "-11367A", - "-11368A", - "-11369T", - "-11370C", - "-11371T", - "-11372A", - "-11373A", - "-11374T", - "-11375G", - "-11376T", - "-11377A", - "-11378G", - "-11379G", - "-11380T", - "-11381T", - "-11382T", - "-11383A", - "-11384T", - "-11385G", - "-11386A", - "-11387C", - "-11388A", - "-11389T", - "-11390A", - "-11391A", - "-11392T", - "-11393A", - "-11394G", - "-11395C", - "-11396A", - "-11397T", - "-11398T", - "-11399T", - "-11400T", - "-11401C", - "-11402A", - "-11403G", - "-11404C", - "-11405A", - "-11406G", - "-11407T", - "-11408T", - "-11409C", - "-11410A", - "-11411A", - "-11412T", - "-11413G", - "-11414T", - "-11415T", - "-11416T", - "-11417C", - "-11418T", - "-11419A", - "-11420G", - "-11421A", - "-11422T", - "-11423T", - "-11424C", - "-11425G", - "-11426T", - "-11427T", - "-11428G", - "-11429A", - "-11430T", - "-11431G", - "-11432G", - "-11433C", - "-11434A", - "-11435A", - "-11436T", - "-11437G", - "-11438G", - "-11439T", - "-11440T", - "-11441A", - "-11442T", - "-11443A", - "-11444C", - "-11445A", - "-11446T", - "-11447G", - "-11448T", - "-11449A", - "-11450T", - "-11451A", - "-11452T", - "-11453C", - "-11454C", - "-11455G", - "-11456T", - "-11457T", - "-11458A", - "-11459T", - "-11460T", - "-11461T", - "-11462G", - "-11463A", - "-11464T", - "-11465C", - "-11466T", - "-11467A", - "-11468A", - "-11469T", - "-11470G", - "-11471T", - "-11472T", - "-11473G", - "-11474A", - "-11475C", - "-11476A", - "-11477T", - "-11478C", - "-11479T", - "-11480G", - "-11481A", - "-11482A", - "-11483C", - "-11484C", - "-11485G", - "-11486G", - "-11487A", - "-11488T", - "-11489T", - "-11490C", - "-11491T", - "-11492A", - "-11493G", - "-11494C", - "-11495A", - "-11496G", - "-11497T", - "-11498A", - "-11499A", - "-11500A", - "-11501G", - "-11502A", - "-11503T", - "-11504A", - "-11505C", - "-11506T", - "-11507A", - "-11508G", - "-11509A", - "-11510G", - "-11511A", - "-11512T", - "-11513T", - "-11514G", - "-11515T", - "-11516T", - "-11517T", - "-11518A", - "-11519T", - "-11520T", - "-11521A", - "-11522T", - "-11523A", - "-11524T", - "-11525C", - "-11526T", - "-11527A", - "-11528A", - "-11529C", - "-11530A", - "-11531G", - "-11532C", - "-11533C", - "-11534T", - "-11535T", - "-11536G", - "-11537T", - "-11538G", - "-11539A", - "-11540A", - "-11541G", - "-11542A", - "-11543A", - "-11544G", - "-11545T", - "-11546G", - "-11547T", - "-11548T", - "-11549T", - "-11550C", - "-11551T", - "-11552C", - "-11553C", - "-11554T", - "-11555C", - "-11556G", - "-11557T", - "-11558T", - "-11559T", - "-11560G", - "-11561T", - "-11562C", - "-11563A", - "-11564A", - "-11565T", - "-11566C", - "-11567A", - "-11568T", - "-11569G", - "-11570T", - "-11571T", - "-11572A", - "-11573A", - "-11574T", - "-11575G", - "-11576T", - "-11577C", - "-11578T", - "-11579T", - "-11580T", - "-11581A", - "-11582A", - "-11583G", - "-11584A", - "-11585T", - "-11586A", - "-11587A", - "-11588G", - "-11589G", - "-11590T", - "-11591A", - "-11592G", - "-11593A", - "-11594C", - "-11595A", - "-11596A", - "-11597A", - "-11598T", - "-11599G", - "-11600T", - "-11601T", - "-11602T", - "-11603A", - "-11604T", - "-11605A", - "-11606G", - "-11607T", - "-11608A", - "-11609C", - "-11610T", - "-11611A", - "-11612A", - "-11613G", - "-11614A", - "-11615A", - "-11616T", - "-11617T", - "-11618G", - "-11619G", - "-11620G", - "-11621C", - "-11622A", - "-11623A", - "-11624A", - "-11625C", - "-11626A", - "-11627T", - "-11628A", - "-11629A", - "-11630G", - "-11631A", - "-11632C", - "-11633A", - "-11634T", - "-11635G", - "-11636T", - "-11637C", - "-11638A", - "-11639C", - "-11640A", - "-11641A", - "-11642A", - "-11643G", - "-11644A", - "-11645C", - "-11646C", - "-11647C", - "-11648T", - "-11649T", - "-11650T", - "-11651T", - "-11652T", - "-11653G", - "-11654T", - "-11655A", - "-11656T", - "-11657G", - "-11658T", - "-11659A", - "-11660T", - "-11661A", - "-11662A", - "-11663G", - "-11664T", - "-11665G", - "-11666T", - "-11667A", - "-11668G", - "-11669A", - "-11670A", - "-11671A", - "-11672T", - "-11673T", - "-11674A", - "-11675T", - "-11676A", - "-11677A", - "-11678C", - "-11679A", - "-11680T", - "-11681C", - "-11682C", - "-11683A", - "-11684T", - "-11685A", - "-11686G", - "-11687T", - "-11688T", - "-11689G", - "-11690G", - "-11691A", - "-11692T", - "-11693T", - "-11694C", - "-11695A", - "-11696C", - "-11697A", - "-11698T", - "-11699A", - "-11700G", - "-11701G", - "-11702T", - "-11703G", - "-11704T", - "-11705C", - "-11706C", - "-11707A", - "-11708A", - "-11709T", - "-11710C", - "-11711G", - "-11712G", - "-11713G", - "-11714A", - "-11715T", - "-11716C", - "-11717T", - "-11718C", - "-11719T", - "-11720C", - "-11721C", - "-11722A", - "-11723T", - "-11724C", - "-11725A", - "-11726T", - "-11727C", - "-11728G", - "-11729A", - "-11730G", - "-11731A", - "-11732T", - "-11733G", - "-11734A", - "-11735T", - "-11736T", - "-11737G", - "-11738A", - "-11739C", - "-11740G", - "-11741G", - "-11742C", - "-11743A", - "-11744T", - "-11745C", - "-11746T", - "-11747C", - "-11748C", - "-11749C", - "-11750C", - "-11751C", - "-11752T", - "-11753T", - "-11754C", - "-11755C", - "-11756T", - "-11757T", - "-11758T", - "-11759T", - "-11760T", - "-11761T", - "-11762A", - "-11763G", - "-11764T", - "-11765A", - "-11766G", - "-11767A", - "-11768T", - "-11769A", - "-11770T", - "-11771T", - "-11772T", - "-11773C", - "-11774A", - "-11775T", - "-11776C", - "-11777G", - "-11778T", - "-11779G", - "-11780T", - "-11781A", - "-11782A", - "-11783G", - "-11784A", - "-11785A", - "-11786T", - "-11787C", - "-11788A", - "-11789A", - "-11790T", - "-11791A", - "-11792T", - "-11793T", - "-11794A", - "-11795A", - "-11796T", - "-11797A", - "-11798T", - "-11799T", - "-11800T", - "-11801C", - "-11802T", - "-11803A", - "-11804A", - "-11805A", - "-11806G", - "-11807T", - "-11808A", - "-11809T", - "-11810C", - "-11811T", - "-11812G", - "-11813T", - "-11814G", - "-11815T", - "-11816A", - "-11817T", - "-11818A", - "-11819G", - "-11820C", - "-11821C", - "-11822T", - "-11823C", - "-11824T", - "-11825T", - "-11826T", - "-11827A", - "-11828T", - "-11829T", - "-11830T", - "-11831A", - "-11832C", - "-11833C", - "-11834A", - "-11835C", - "-11836A", - "-11837G", - "-11838C", - "-11839T", - "-11840C", - "-11841C", - "-11842A", - "-11843T", - "-11844A", - "-11845T", - "-11846T", - "-11847C", - "-11848C", - "-11849A", - "-11850A", - "-11851C", - "-11852A", - "-11853T", - "-11854G", - "-11855C", - "-11856A", - "-11857T", - "-11858T", - "-11859C", - "-11860C", - "-11861A", - "-11862C", - "-11863T", - "-11864A", - "-11865G", - "-11866A", - "-11867G", - "-11868G", - "-11869G", - "-11870A", - "-11871T", - "-11872A", - "-11873T", - "-11874C", - "-11875G", - "-11876A", - "-11877T", - "-11878A", - "-11879T", - "-11880C", - "-11881G", - "-11882C", - "-11883C", - "-11884G", - "-11885A", - "-11886A", - "-11887T", - "-11888G", - "-11889T", - "-11890C", - "-11891A", - "-11892T", - "-11893A", - "-11894T", - "-11895A", - "-11896C", - "-11897T", - "-11898C", - "-11899A", - "-11900A", - "-11901T", - "-11902T", - "-11903A", - "-11904G", - "-11905T", - "-11906A", - "-11907T", - "-11908A", - "-11909T", - "-11910G", - "-11911T", - "-11912T", - "-11913G", - "-11914G", - "-11915A", - "-11916G", - "-11917G", - "-11918A", - "-11919C", - "-11920A", - "-11921T", - "-11922C", - "-11923C", - "-11924G", - "-11925A", - "-11926G", - "-11927T", - "-11928T", - "-11929C", - "-11930A", - "-11931T", - "-11932T", - "-11933G", - "-11934T", - "-11935T", - "-11936T", - "-11937T", - "-11938C", - "-11939A", - "-11940A", - "-11941T", - "-11942A", - "-11943T", - "-11944C", - "-11945A", - "-11946A", - "-11947A", - "-11948G", - "-11949A", - "-11950G", - "-11951A", - "-11952T", - "-11953G", - "-11954G", - "-11955T", - "-11956T", - "-11957T", - "-11958C", - "-11959C", - "-11960T", - "-11961T", - "-11962A", - "-11963T", - "-11964C", - "-11965A", - "-11966T", - "-11967T", - "-11968T", - "-11969C", - "-11970T", - "-11971C", - "-11972C", - "-11973A", - "-11974T", - "-11975A", - "-11976G", - "-11977T", - "-11978G", - "-11979G", - "-11980T", - "-11981A", - "-11982C", - "-11983A", - "-11984A", - "-11985T", - "-11986A", - "-11987C", - "-11988T", - "-11989A", - "-11990C", - "-11991A", - "-11992C", - "-11993A", - "-11994T", - "-11995T", - "-11996A", - "-11997T", - "-11998T", - "-11999C", - "-12000C", - "-12001G", - "-12002T", - "-12003A", - "-12004C", - "-12005G", - "-12006G", - "-12007C", - "-12008T", - "-12009T", - "-12010T", - "-12011C", - "-12012C", - "-12013A", - "-12014T", - "-12015T", - "-12016C", - "-12017T", - "-12018C", - "-12019C", - "-12020A", - "-12021A", - "-12022A", - "-12023A", - "-12024A", - "-12025C", - "-12026A", - "-12027A", - "-12028T", - "-12029T", - "-12030T", - "-12031T", - "-12032A", - "-12033C", - "-12034C", - "-12035A", - "-12036A", - "-12037A", - "-12038T", - "-12039C", - "-12040T", - "-12041A", - "-12042A", - "-12043A", - "-12044T", - "-12045C", - "-12046T", - "-12047A", - "-12048C", - "-12049A", - "-12050T", - "-12051C", - "-12052T", - "-12053T", - "-12054T", - "-12055A", - "-12056T", - "-12057T", - "-12058G", - "-12059T", - "-12060A", - "-12061T", - "-12062C", - "-12063T", - "-12064A", - "-12065T", - "-12066A", - "-12067A", - "-12068T", - "-12069C", - "-12070A", - "-12071C", - "-12072T", - "-12073A", - "-12074T", - "-12075T", - "-12076T", - "-12077A", - "-12078G", - "-12079A", - "-12080T", - "-12081A", - "-12082A", - "-12083T", - "-12084C", - "-12085A", - "-12086G", - "-12087C", - "-12088C", - "-12089A", - "-12090T", - "-12091A", - "-12092A", - "-12093T", - "-12094T", - "-12095C", - "-12096C", - "-12097T", - "-12098C", - "-12099G", - "-12100A", - "-12101G", - "-12102T", - "-12103G", - "-12104C", - "-12105A", - "-12106A", - "-12107C", - "-12108A", - "-12109T", - "-12110G", - "-12111T", - "-12112T", - "-12113A", - "-12114G", - "-12115A", - "-12116T", - "-12117C", - "-12118G", - "-12119T", - "-12120C", - "-12121T", - "-12122A", - "-12123T", - "-12124A", - "-12125T", - "-12126A", - "-12128G", - "-12129A", - "-12130A", - "-12131T", - "-12132A", - "-12133A", - "-12134G", - "-12135C", - "-12136C", - "-12137G", - "-12138T", - "-12139G", - "-12140T", - "-12141T", - "-12142A", - "-12143T", - "-12144C", - "-12145T", - "-12147T", - "-12148T", - "-12149C", - "-12150C", - "-12151T", - "-12154C", - "-12156T", - "-12178A", - "-12179T", - "-12180C", - "-12181T", - "-12182A", - "-12183T", - "-12184A", - "-12185T", - "-12186G", - "-12187A", - "-12188G", - "-12189A", - "-12190T", - "-12191G", - "-12192A", - "-12193C", - "-12194T", - "-12195T", - "-12196A", - "-12197A", - "-12198T", - "-12199A", - "-12200T", - "-12201A", - "-12202A", - "-12203T", - "-12204A", - "-12205T", - "-12206T", - "-12207G", - "-12208A", - "-12209A", - "-12210G", - "-12211A", - "-12212G", - "-12213C", - "-12214T", - "-12215G", - "-12216T", - "-12217A", - "-12218C", - "-12219A", - "-12220A", - "-12221T", - "-12222A", - "-12223G", - "-12224T", - "-12225T", - "-12226T", - "-12227T", - "-12228T", - "-12229A", - "-12230T", - "-12231C", - "-12232T", - "-12233A", - "-12234T", - "-12235A", - "-12236G", - "-12237A", - "-12238A", - "G33889A", - "A178901-", - "G178902-", - "A178903-", - "T178904-", - "A178905-", - "C178906-", - "A178907-", - "T178908-", - "T178909-", - "T178910-", - "A178911-", - "A178912-", - "T178913-", - "G178914-", - "T178915-", - "G178916-", - "C178917-", - "T178918-", - "T178919-", - "A178920-", - "C178921-", - "G178922-", - "G178923-", - "A178924-", - "A178925-", - "C178926-", - "A178927-", - "T178928-", - "A178929-", - "T178930-", - "A178931-", - "T178932-", - "T178933-", - "T178934-", - "A178935-", - "G178936-", - "A178937-", - "A178938-", - "A178939-", - "C178940-", - "A178941-", - "T178942-", - "C178943-", - "T178944-", - "A178945-", - "C178946-", - "T178947-", - "A178948-", - "A178949-", - "C178950-", - "G178951-", - "A178952-", - "T178953-", - "T178954-", - "T178955-", - "T178956-", - "T178957-", - "T178958-", - "A178959-", - "T178960-", - "G178961-", - "C178962-", - "T178963-", - "T178964-", - "G178965-", - "T178966-", - "A178967-", - "T178968-", - "T178969-", - "A178970-", - "T178971-", - "T178972-" - ], - "OPG023": [ - "X221S", - "-222S", - "-223I", - "-224D", - "-225K", - "-226N", - "-227Y", - "-228C", - "-229T", - "-230A", - "-231L", - "-232Q", - "-233Y", - "-234Y", - "-235I", - "-236K", - "-237S", - "-238S", - "-239H", - "-240I", - "-241D", - "-249X", - "-250X", - "-251G", - "-252X", - "-253D", - "-254N", - "-255T", - "-256A", - "-257Y", - "-258X", - "-259Y", - "-260I", - "-261D", - "-262D", - "-263L", - "-264T", - "-265C", - "-266C", - "-267T", - "-268R", - "-269G", - "-270I", - "-271M", - "-272A", - "-273D", - "-274Y", - "-275L", - "-276N", - "-277S", - "-278D", - "-279Y", - "-280R", - "-281Y", - "-282N", - "-283K", - "-284D", - "-285V", - "-286D", - "-287L", - "-288D", - "-289L", - "-290V", - "-291K", - "-292L", - "-293F", - "-294L", - "-295E", - "-296N", - "-297G", - "-298K", - "-299P", - "-300Y", - "-301G", - "-302I", - "-303M", - "-304C", - "-305S", - "-306I", - "-307V", - "-308P", - "-309L", - "-310W", - "-311R", - "-312N", - "-313D", - "-314K", - "-315E", - "-316T", - "-317I", - "-318S", - "-319L", - "-320I", - "-321L", - "-322K", - "-323T", - "-324M", - "-325N", - "-326S", - "-327D", - "-328V", - "-329L", - "-330Q", - "-331H", - "-332I", - "-333L", - "-334I", - "-335E", - "-336Y", - "-337M", - "-338T", - "-339F", - "-340G", - "-341D", - "-342I", - "-343D", - "-344I", - "-345P", - "-346L", - "-347V", - "-348E", - "-349C", - "-350M", - "-351L", - "-352E", - "-353Y", - "-354G", - "-355A", - "-356V", - "-357V", - "-358N", - "-359K", - "-360E", - "-361A", - "-362I", - "-363H", - "-364R", - "-365Y", - "-366F", - "-367R", - "-368N", - "-369I", - "-370N", - "-371I", - "-372D", - "-373S", - "-374Y", - "-375T", - "-376M", - "-377K", - "-378Y", - "-379L", - "-380L", - "-381K", - "-382K", - "-383E", - "-384G", - "-385G", - "-386D", - "-387A", - "-388V", - "-389N", - "-390H", - "-391L", - "-392D", - "-393D", - "-394G", - "-395E", - "-396I", - "-397P", - "-398I", - "-399G", - "-400H", - "-401L", - "-402C", - "-403E", - "-404S", - "-405N", - "-406Y", - "-407G", - "-408C", - "-409Y", - "-410N", - "-411F", - "-412Y", - "-413T", - "-414Y", - "-415T", - "-416Y", - "-417K", - "-418K", - "-419G", - "-420L", - "-421C", - "-422D", - "-423M", - "-424S", - "-425Y", - "-426V", - "-427C", - "-428P", - "-429I", - "-430L", - "-431S", - "-432T", - "-433I", - "-434N", - "-435I", - "-436C", - "-437L", - "-438P", - "-439Y", - "-440L", - "-441K", - "-442D", - "-443I", - "-444N", - "-445M", - "-446I", - "-447D", - "-448K", - "-449R", - "-450G", - "-451E", - "-452T", - "-453L", - "-454L", - "-455H", - "-456K", - "-457A", - "-458V", - "-459R", - "-460Y", - "-461N", - "-462K", - "-463Q", - "-464S", - "-465L", - "-466V", - "-467S", - "-468L", - "-469L", - "-470L", - "-471E", - "-472S", - "-473G", - "-474S", - "-475D", - "-476V", - "-477N", - "-478I", - "-479R", - "-480S", - "-481N", - "-482N", - "-483G", - "-484Y", - "-485T", - "-486C", - "-487I", - "-488T", - "-489I", - "-490A", - "-491I", - "-492N", - "-493E", - "-494S", - "-495R", - "-496N", - "-497I", - "-498E", - "-499L", - "-500L", - "-501K", - "-502M", - "-503L", - "-504L", - "-505C", - "-506H", - "-507K", - "-508P", - "-509T", - "-510L", - "-511D", - "-512C", - "-513V", - "-514I", - "-515D", - "-516S", - "-517L", - "-518S", - "-519E", - "-520V", - "-521S", - "-522N" - ], - "OPG052": [ - "S36L" - ] - }, - "labels": { - "aa": "OPG023: X221S, -222S, -223I, -224D, -225K, -226N, -227Y, -228C, -229T, -230A, -231L, -232Q, -233Y, -234Y, -235I, -236K, -237S, -238S, -239H, -240I, -241D, -249X, -250X, -251G, -252X, -253D, -254N, -255T, -256A, -257Y, -258X, -259Y, -260I, -261D, -262D, -263L, -264T, -265C, -266C, -267T, -268R, -269G, -270I, -271M, -272A, -273D, -274Y, -275L, -276N, -277S, -278D, -279Y, -280R, -281Y, -282N, -283K, -284D, -285V, -286D, -287L, -288D, -289L, -290V, -291K, -292L, -293F, -294L, -295E, -296N, -297G, -298K, -299P, -300Y, -301G, -302I, -303M, -304C, -305S, -306I, -307V, -308P, -309L, -310W, -311R, -312N, -313D, -314K, -315E, -316T, -317I, -318S, -319L, -320I, -321L, -322K, -323T, -324M, -325N, -326S, -327D, -328V, -329L, -330Q, -331H, -332I, -333L, -334I, -335E, -336Y, -337M, -338T, -339F, -340G, -341D, -342I, -343D, -344I, -345P, -346L, -347V, -348E, -349C, -350M, -351L, -352E, -353Y, -354G, -355A, -356V, -357V, -358N, -359K, -360E, -361A, -362I, -363H, -364R, -365Y, -366F, -367R, -368N, -369I, -370N, -371I, -372D, -373S, -374Y, -375T, -376M, -377K, -378Y, -379L, -380L, -381K, -382K, -383E, -384G, -385G, -386D, -387A, -388V, -389N, -390H, -391L, -392D, -393D, -394G, -395E, -396I, -397P, -398I, -399G, -400H, -401L, -402C, -403E, -404S, -405N, -406Y, -407G, -408C, -409Y, -410N, -411F, -412Y, -413T, -414Y, -415T, -416Y, -417K, -418K, -419G, -420L, -421C, -422D, -423M, -424S, -425Y, -426V, -427C, -428P, -429I, -430L, -431S, -432T, -433I, -434N, -435I, -436C, -437L, -438P, -439Y, -440L, -441K, -442D, -443I, -444N, -445M, -446I, -447D, -448K, -449R, -450G, -451E, -452T, -453L, -454L, -455H, -456K, -457A, -458V, -459R, -460Y, -461N, -462K, -463Q, -464S, -465L, -466V, -467S, -468L, -469L, -470L, -471E, -472S, -473G, -474S, -475D, -476V, -477N, -478I, -479R, -480S, -481N, -482N, -483G, -484Y, -485T, -486C, -487I, -488T, -489I, -490A, -491I, -492N, -493E, -494S, -495R, -496N, -497I, -498E, -499L, -500L, -501K, -502M, -503L, -504L, -505C, -506H, -507K, -508P, -509T, -510L, -511D, -512C, -513V, -514I, -515D, -516S, -517L, -518S, -519E, -520V, -521S, -522N; OPG052: S36L" - } - } - }, - { - "name": "Monkeypox/PT0020/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J.D., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Carvalho,I.L., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J.D., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Carvalho,I.L., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0020/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON649713" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-19" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0451/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0451/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555532" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-04" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G159148A" - ], - "OPG185": [ - "D78N" - ] - }, - "labels": { - "aa": "OPG185: D78N" - } - } - } - ] - }, - { - "name": "NODE_0000069", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C34432T" - ], - "OPG053": [ - "E87K" - ] - }, - "labels": { - "aa": "OPG053: E87K" - } - }, - "children": [ - { - "name": "NODE_0000070", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G155157A", - "A196431-", - "C196432-" - ], - "OPG181": [ - "R249K" - ] - }, - "labels": { - "aa": "OPG181: R249K" - } - }, - "children": [ - { - "name": "Monkeypox/PT0144/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0144/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP324463" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-07" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0156/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0156/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP324473" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-04" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G560-", - "A561-" - ] - } - } - }, - { - "name": "Monkeypox/PT0500/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0500/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555574" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-12" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000071", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G37974A", - "C47521T", - "G90736A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG056": [ - "S354L" - ], - "OPG111": [ - "D158N" - ] - }, - "labels": { - "aa": "OPG056: S354L; OPG111: D158N" - } - }, - "children": [ - { - "name": "NY-NYCPHL-000158", - "node_attrs": { - "div": 7, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000158" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ419004" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-29" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A74149T", - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG094": [ - "T124S" - ] - }, - "labels": { - "aa": "OPG094: T124S" - } - } - }, - { - "name": "NODE_0000072", - "node_attrs": { - "div": 7, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G21065A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150567A" - ] - } - }, - "children": [ - { - "name": "NY-NYCPHL-000198", - "node_attrs": { - "div": 7, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000198" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469047" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-01" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150557A", - "-150558T" - ] - } - } - }, - { - "name": "NY-NYCPHL-001101", - "node_attrs": { - "div": 7, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-001101" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469275" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-05" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000073", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G111029A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - }, - "labels": { - "clade": "B.1.6" - } - }, - "children": [ - { - "name": "LIM-INS-003", - "node_attrs": { - "div": 1, - "author": { - "author": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Mestanza,O., Lope,P., Nunez,A.", - "value": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Mestanza,O., Lope,P., Nunez,A." - }, - "strain_original": { - "value": "LIM-INS-003" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP289783" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Peru" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-27" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "LIM-INS-016", - "node_attrs": { - "div": 3, - "author": { - "author": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Lope,P., Arotinco,G.", - "value": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Lope,P., Arotinco,G." - }, - "strain_original": { - "value": "LIM-INS-016" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP320554" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Peru" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-09" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G25098A", - "A34289G" - ] - } - } - }, - { - "name": "MPX_3U0idu_9000254", - "node_attrs": { - "div": 1, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_3U0idu_9000254" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415224" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-22752-O", - "node_attrs": { - "div": 2, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-22752-O" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP431402" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-18" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G15814A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "9000387", - "node_attrs": { - "div": 3, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "9000387" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536765" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G59112A", - "C87978T" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-24910-O", - "node_attrs": { - "div": 1, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-24910-O" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP642385" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-09" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "LBMB-UTP_MP-004_TOL", - "node_attrs": { - "div": 4, - "author": { - "author": "Orjuela,M., Tabares,F.A., Anacona,J.D., Lopez,P.A., Zuluaga-Velez,A., Sepulveda-Arias,J.C.", - "value": "Orjuela,M., Tabares,F.A., Anacona,J.D., Lopez,P.A., Zuluaga-Velez,A., Sepulveda-Arias,J.C." - }, - "strain_original": { - "value": "LBMB-UTP_MP-004_TOL" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ148463" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-21" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G22646A", - "C85452T", - "G132863A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-" - ], - "OPG038": [ - "P172S" - ], - "OPG106": [ - "G16E" - ] - }, - "labels": { - "aa": "OPG038: P172S; OPG106: G16E" - } - } - }, - { - "name": "DC_INS_MPX-1122-H", - "node_attrs": { - "div": 2, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Rosales,A., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Rosales,A., Mercado-Reyes,M.M." - }, - "strain_original": { - "value": "DC_INS_MPX-1122-H" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ197863" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-22" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G544-", - "G545-", - "T546-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "C151204T", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-" - ] - } - } - }, - { - "name": "hMpxV/USA/CA-CDPH-1MPX1000120/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J." - }, - "strain_original": { - "value": "hMpxV/USA/CA-CDPH-1MPX1000120/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ348868" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-20" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150364A", - "C166930T" - ], - "OPG176": [ - "E186K" - ], - "OPG192": [ - "S67L" - ] - }, - "labels": { - "aa": "OPG176: E186K; OPG192: S67L" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00408/2023", - "node_attrs": { - "div": 5, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00408/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503831" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-01-11" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G10945A", - "G39515A", - "C44627T", - "G56276A", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A196604-" - ], - "OPG064": [ - "M424I" - ] - }, - "labels": { - "aa": "OPG064: M424I" - } - } - }, - { - "name": "LIM-INS-021", - "node_attrs": { - "div": 1, - "author": { - "author": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Lope,P., Arotinco,G.", - "value": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Lope,P., Arotinco,G." - }, - "strain_original": { - "value": "LIM-INS-021" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP320555" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Peru" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-09" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "LIM-INS-001", - "node_attrs": { - "div": 1, - "author": { - "author": "Silva,I., Jimenez,V., Hurtado,V., Barcena,L.", - "value": "Silva,I., Jimenez,V., Hurtado,V., Barcena,L." - }, - "strain_original": { - "value": "LIM-INS-001" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP289782" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Peru" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-25" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "-196601A", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "LIM-INS008", - "node_attrs": { - "div": 1, - "author": { - "author": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Lope,P., Arotinco,G.", - "value": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Lope,P., Arotinco,G." - }, - "strain_original": { - "value": "LIM-INS008" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP320548" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Peru" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-01" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000074", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C170573T" - ], - "OPG198": [ - "S179L" - ] - }, - "labels": { - "aa": "OPG198: S179L" - } - }, - "children": [ - { - "name": "Monkeypox virus/Human/USA/CA-LACPHL-MA00388/2022", - "node_attrs": { - "div": 8, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "Monkeypox virus/Human/USA/CA-LACPHL-MA00388/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ330995" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-12-10" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A488-", - "C489-", - "G490-", - "C35216T", - "C100640T", - "C105831T", - "G134403A", - "C140075T", - "G158161A", - "T175981A", - "A178020-", - "T178021-", - "A178022-", - "A178023-", - "T178024-", - "G178025-", - "A178026-", - "A178027-", - "T178028-", - "A178029-", - "C178030-", - "A178031-", - "C178032-", - "A178033-", - "T178034-", - "A178035-", - "C178036-", - "A178037-", - "A178038-", - "C178039-", - "G178040-", - "T178041-", - "T178042-", - "T178043-", - "T178044-", - "T178045-", - "T178046-", - "T178047-", - "T178048-", - "A178049-", - "A178050-", - "T178051-", - "C178052-", - "T178053-", - "T178054-", - "A178055-", - "G178056-", - "A178057-", - "T178058-", - "A178059-", - "T178060-", - "A178061-", - "A178062-", - "C178063-", - "A178064-", - "C178065-", - "T178066-", - "A178067-", - "A178068-", - "T178069-", - "T178070-", - "A178071-", - "C178072-", - "A178073-", - "T178074-", - "C178075-", - "A178076-", - "A178077-", - "G178078-", - "A178079-", - "T178080-", - "T178081-", - "A178082-", - "T178083-", - "A178084-", - "T178085-", - "A178086-", - "T178087-", - "T178088-", - "G178089-", - "A178090-", - "A178091-", - "A178092-", - "T178093-", - "C178094-", - "G178095-", - "T178096-", - "A178097-", - "A178098-", - "T178099-", - "T178100-", - "T178101-", - "G178102-", - "A178103-", - "G178104-", - "T178105-", - "T178106-", - "G178107-", - "T178108-", - "C178109-", - "T178110-", - "G178111-", - "A178112-", - "T178113-", - "C178114-", - "A178115-", - "T178116-" - ], - "OPG054": [ - "D261N" - ], - "OPG159": [ - "S103F" - ], - "OPG205": [ - "F109Y" - ] - }, - "labels": { - "aa": "OPG054: D261N; OPG159: S103F; OPG205: F109Y" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00422/2022", - "node_attrs": { - "div": 9, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00422/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503815" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-12-03" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C14098T", - "C84063T", - "G97749A", - "G142493A", - "G151324A", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "C187332T", - "G188726A" - ], - "OPG163": [ - "D98N" - ] - }, - "labels": { - "aa": "OPG163: D98N" - } - } - } - ] - }, - { - "name": "NODE_0000075", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G63811A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G167862A", - "C170130T", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "A178869-", - "T178870-", - "T178872-", - "T178873-", - "A178874-", - "A178876-", - "T178877-", - "T178878-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-" - ], - "OPG193": [ - "D177N" - ] - }, - "labels": { - "aa": "OPG193: D177N" - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-29396O", - "node_attrs": { - "div": 4, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-29396O" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ696077" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-27" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C178861-", - "C178862-", - "G178868-", - "G178871-", - "C178875-" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-30518C", - "node_attrs": { - "div": 5, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-30518C" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ696099" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-09" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G132863A", - "-178863A", - "-178864T", - "-178865A", - "-178866A", - "-178867T", - "-178869A", - "-178870T", - "-178872T", - "-178873T", - "-178874A", - "-178876A", - "-178877T", - "-178878T" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000084", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C18133T", - "G67611A", - "G130231A", - "G159277A", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196603A" - ], - "OPG185": [ - "E121K" - ] - }, - "labels": { - "aa": "OPG185: E121K", - "clade": "B.1.11" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-070499/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-070499/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP169336" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T" - ] - } - } - }, - { - "name": "MAG-UNIMOL-MPX-292982-L", - "node_attrs": { - "div": 4, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "strain_original": { - "value": "MAG-UNIMOL-MPX-292982-L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP390178" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-20" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-", - "A196603-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI404", - "node_attrs": { - "div": 5, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI404" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP524006" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "G182634A" - ], - "OPG210": [ - "D427N" - ] - }, - "labels": { - "aa": "OPG210: D427N" - } - } - }, - { - "name": "MPXV-USA-IL-IDPH-037", - "node_attrs": { - "div": 4, - "author": { - "author": "Gagnon,K.T.", - "value": "Gagnon,K.T." - }, - "strain_original": { - "value": "MPXV-USA-IL-IDPH-037" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536698" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-17" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-196601A", - "-196602A" - ] - } - } - }, - { - "name": "MPX/Human/USA/CA-LACPHL-MA00148/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPX/Human/USA/CA-LACPHL-MA00148/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP539933" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-12" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-" - ] - } - } - }, - { - "name": "Monkeypox/PT0466/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0466/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555545" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-05" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ] - } - } - }, - { - "name": "MPXV_USA_2022_WI0001", - "node_attrs": { - "div": 4, - "author": { - "author": "Gigante,C.M., Segaloff,H., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Florek,K., Li,Y.", - "value": "Gigante,C.M., Segaloff,H., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Florek,K., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_WI0001" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP603002" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "A4680-", - "A4681-", - "C4682-", - "T4683-", - "A4684-", - "A4685-", - "C4686-", - "T4687-", - "T4688-", - "A4689-", - "T4690-", - "G4691-", - "A4692-", - "C4693-", - "T4694-", - "T4695-", - "A4696-", - "A4697-", - "C4698-", - "T4699-", - "A4700-", - "A4701-", - "C4702-", - "T4703-", - "T4704-", - "A4705-", - "T4706-", - "G4707-", - "A4708-", - "C4709-", - "T4710-", - "T4711-", - "A192404-", - "G192405-", - "T192406-", - "C192407-", - "A192408-", - "T192409-", - "A192410-", - "A192411-", - "G192412-", - "T192413-", - "T192414-", - "A192415-", - "G192416-", - "T192417-", - "T192418-", - "A192419-", - "A192420-", - "G192421-", - "T192422-", - "C192423-", - "A192424-", - "T192425-", - "A192426-", - "A192427-", - "G192428-", - "T192429-", - "T192430-", - "A192431-", - "G192432-", - "T192433-", - "T192434-", - "A192435-" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-25510E", - "node_attrs": { - "div": 5, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-25510E" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP642421" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-03" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C90842T", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ], - "OPG111": [ - "S193F" - ] - }, - "labels": { - "aa": "OPG111: S193F" - } - } - }, - { - "name": "SAN_INS_MPX_0973_L", - "node_attrs": { - "div": 7, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "strain_original": { - "value": "SAN_INS_MPX_0973_L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP819960" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-17" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T19741-", - "A19742-", - "G19743-", - "G19744-", - "C19745-", - "G19746-", - "G27840A", - "C64404T", - "C96810T", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-" - ], - "OPG034": [ - "T87X", - "P88-", - "K89X", - "*215X" - ], - "OPG043": [ - "S39F" - ], - "OPG083": [ - "D105N" - ] - }, - "labels": { - "aa": "OPG034: T87X, P88-, K89X, *215X; OPG043: S39F; OPG083: D105N" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00296/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00296/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP890530" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-04" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G154531A", - "C174287T", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00344/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00344/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP920682" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-09" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G39327A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G177273A", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ], - "OPG057": [ - "A290V" - ], - "OPG205": [ - "D540N" - ] - }, - "labels": { - "aa": "OPG057: A290V; OPG205: D540N" - } - } - }, - { - "name": "LBMB-UTP_MP-010_TOL", - "node_attrs": { - "div": 8, - "author": { - "author": "Tabares,F.A., Anacona,J.D., Lopez,P.A., Orjuela,M., Zuluaga-Velez,A., Sepulveda-Arias,J.C.", - "value": "Tabares,F.A., Anacona,J.D., Lopez,P.A., Orjuela,M., Zuluaga-Velez,A., Sepulveda-Arias,J.C." - }, - "strain_original": { - "value": "LBMB-UTP_MP-010_TOL" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ148467" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-13" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T509-", - "T510-", - "A511-", - "C58682T", - "C92819T", - "C170573T", - "G178744A", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-" - ], - "OPG078": [ - "G44S" - ], - "OPG198": [ - "S179L" - ] - }, - "labels": { - "aa": "OPG078: G44S; OPG198: S179L" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-28220C", - "node_attrs": { - "div": 4, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-28220C" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ261700" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-13" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T" - ] - } - } - }, - { - "name": "NY-NYCPHL-000171", - "node_attrs": { - "div": 6, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000171" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469161" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-28" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G23528A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "G179412A" - ], - "OPG208": [ - "M49I" - ] - }, - "labels": { - "aa": "OPG208: M49I" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-3668E", - "node_attrs": { - "div": 7, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-3668E" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ957072" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-02-16" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C35308T", - "G71777A", - "C120979T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T" - ], - "OPG054": [ - "R230H" - ], - "OPG138": [ - "D52N" - ] - }, - "labels": { - "aa": "OPG054: R230H; OPG138: D52N" - } - } - }, - { - "name": "MPXV/UZ_REGA_113", - "node_attrs": { - "div": 7, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_113" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035719" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-28" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "C142797T", - "C167995T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "G189258A", - "A196603-" - ], - "OPG164": [ - "S7L" - ], - "OPG193": [ - "S221F" - ] - }, - "labels": { - "aa": "OPG164: S7L; OPG193: S221F" - } - } - }, - { - "name": "MPXV/UZ_REGA_235/Belgium/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_235/Belgium/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR095053" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-12" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "A196603-" - ] - } - } - }, - { - "name": "MPXV_USA_2022_CT0005", - "node_attrs": { - "div": 5, - "author": { - "author": "Li,C.M.", - "value": "Li,C.M." - }, - "strain_original": { - "value": "MPXV_USA_2022_CT0005" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR209313" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C172443T", - "A179074-", - "T179075-", - "G179076-", - "-179101A", - "-179102T", - "-179103T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T" - ] - } - } - }, - { - "name": "MPXV_USA_2022_NE0005", - "node_attrs": { - "div": 7, - "author": { - "author": "Li,C.M.", - "value": "Li,C.M." - }, - "strain_original": { - "value": "MPXV_USA_2022_NE0005" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR209325" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "C169036T", - "C179853T", - "C189459T", - "-196601A", - "-196602A" - ] - } - } - }, - { - "name": "NODE_0000085", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C89777T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T" - ], - "OPG110": [ - "P49L" - ] - }, - "labels": { - "aa": "OPG110: P49L" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-087336/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-087336/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP392550" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T" - ] - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-109000/2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-109000/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP747058" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-XX" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G52594A", - "G176818A", - "A196603-" - ], - "OPG205": [ - "R388Q" - ] - }, - "labels": { - "aa": "OPG205: R388Q" - } - } - } - ] - }, - { - "name": "NODE_0000086", - "node_attrs": { - "div": 5, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G17023A", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-" - ], - "OPG029": [ - "S16F" - ] - }, - "labels": { - "aa": "OPG029: S16F" - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-29706O", - "node_attrs": { - "div": 8, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-29706O" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ696092" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-03" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G74462A", - "C80742T", - "G113382A", - "A196376-", - "T196377-", - "C196378-" - ], - "OPG094": [ - "R228K" - ], - "OPG104": [ - "R93Q" - ] - }, - "labels": { - "aa": "OPG094: R228K; OPG104: R93Q" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-29778O", - "node_attrs": { - "div": 8, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-29778O" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ696093" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-03" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C35308T", - "G102395A", - "G148319A", - "A196603-" - ], - "OPG054": [ - "R230H" - ] - }, - "labels": { - "aa": "OPG054: R230H" - } - } - } - ] - }, - { - "name": "NODE_0000087", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G19458A", - "C185455T" - ], - "OPG034": [ - "S183L" - ], - "OPG210": [ - "S1367L" - ] - }, - "labels": { - "aa": "OPG034: S183L; OPG210: S1367L" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_MO0005", - "node_attrs": { - "div": 7, - "author": { - "author": "Gigante,C., Cleavinger,K., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Sinn,M., Li,Y.", - "value": "Gigante,C., Cleavinger,K., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Sinn,M., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_MO0005" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ721927" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G143138A", - "A179074-", - "T179075-", - "G179076-", - "-179110A", - "-179111T", - "-179112T" - ], - "OPG164": [ - "D121N" - ] - }, - "labels": { - "aa": "OPG164: D121N" - } - } - }, - { - "name": "MPXV_USA_2022_TX0052", - "node_attrs": { - "div": 7, - "author": { - "author": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y.", - "value": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_TX0052" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR209310" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-12-XX" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G74374A", - "A196603-" - ], - "OPG094": [ - "E199K" - ] - }, - "labels": { - "aa": "OPG094: E199K" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000088", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G34308A" - ], - "OPG053": [ - "S128L" - ] - }, - "labels": { - "aa": "OPG053: S128L", - "clade": "B.1.4" - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-2833/2022", - "node_attrs": { - "div": 2, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-2833/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880519" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-13" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T85846C" - ], - "OPG107": [ - "M112T" - ] - }, - "labels": { - "aa": "OPG107: M112T" - } - } - }, - { - "name": "MPXV_USA_2022_CO0003", - "node_attrs": { - "div": 4, - "author": { - "author": "Gigante,C.M., Steidley,B., Seabolt,M.H., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Davizon,E.S., Li,Y.", - "value": "Gigante,C.M., Steidley,B., Seabolt,M.H., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Davizon,E.S., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_CO0003" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP185714" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C18027T", - "T159165C", - "G162156A", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG031": [ - "D268N" - ] - }, - "labels": { - "aa": "OPG031: D268N" - } - } - }, - { - "name": "ATL-UNIMOL-MPX-292896-L", - "node_attrs": { - "div": 2, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "strain_original": { - "value": "ATL-UNIMOL-MPX-292896-L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP390177" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-13" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C176447T", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "NODE_0000089", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C10672T", - "G112481A", - "G163626A" - ], - "OPG022": [ - "E63K" - ] - }, - "labels": { - "aa": "OPG022: E63K" - } - }, - "children": [ - { - "name": "NODE_0000090", - "node_attrs": { - "div": 5, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A87705G", - "A132985-", - "T132987-", - "T132989-", - "T132990-", - "T132991-" - ] - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-4119/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Griffiths,E., Jolly,G., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Griffiths,E., Jolly,G., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-4119/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP279049" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-04" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C132984-", - "G132986-", - "C132988-", - "-179082C", - "-179083A", - "-179084T" - ] - } - } - }, - { - "name": "HRYC_MPXV002", - "node_attrs": { - "div": 8, - "author": { - "author": "Ponce-Alonso,M., Martinez-Garcia,L., Olavarrieta,L., Galan,J.C.", - "value": "Ponce-Alonso,M., Martinez-Garcia,L., Olavarrieta,L., Galan,J.C." - }, - "strain_original": { - "value": "HRYC_MPXV002" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Hospital Ramon y Cajal, Microbiology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR126132" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-03-23" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6376A", - "G11924A", - "G21674A", - "-132985A", - "-132987T", - "-132989T", - "-132990T", - "-132991T", - "A179074-", - "T179075-", - "G179076-", - "-179092A", - "-179093T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "C190834T" - ], - "NBT03_gp174": [ - "S142L" - ], - "OPG023": [ - "S326L" - ], - "OPG037": [ - "L254F" - ] - }, - "labels": { - "aa": "NBT03_gp174: S142L; OPG023: S326L; OPG037: L254F" - } - } - } - ] - }, - { - "name": "NODE_0000091", - "node_attrs": { - "div": 5, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G144478A" - ] - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-3214/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3214/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880511" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-30" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/CAN/UN-NML-4122/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Griffiths,E., Jolly,G., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Griffiths,E., Jolly,G., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-4122/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP279040" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-03" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G82868A" - ] - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-088960/2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-088960/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP392553" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C57650T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "G185991A", - "-196603A" - ], - "OPG077": [ - "E312K" - ], - "OPG210": [ - "D1546N" - ] - }, - "labels": { - "aa": "OPG077: E312K; OPG210: D1546N" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000092", - "node_attrs": { - "div": 5, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C24995T", - "G85774A", - "G148427A", - "G189258A" - ], - "OPG040": [ - "D162N" - ], - "OPG107": [ - "R88K" - ] - }, - "labels": { - "aa": "OPG040: D162N; OPG107: R88K" - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-2906/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-2906/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880505" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-20" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/CAN/UN-NML-2959/2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-2959/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880506" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-22" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G127678A", - "C139901T", - "T179057-", - "T179058-", - "T179059-", - "A179060-", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-" - ], - "OPG149": [ - "M161I" - ], - "OPG159": [ - "S45F" - ] - }, - "labels": { - "aa": "OPG149: M161I; OPG159: S45F" - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3467/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3467/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880515" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-02" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3532/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Marchand-Austin,A., Eshaghi,A., Patel,S.N., Hasso,M., Gubbay,J.B., Olsha,R.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Marchand-Austin,A., Eshaghi,A., Patel,S.N., Hasso,M., Gubbay,J.B., Olsha,R." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3532/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON983163" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-07" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3440/2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Haidl,E., Chapel,M., Tyler,A.D., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Kaplen,B., Antonation,K., Laminman,V., Jolly,G., Croxen,M., Deo,A., Dieu,P., Dong,X., Gill,K., Granger,D., Ferrato,C., Ikkurti,V., Kanji,J., Koleva,P., Li,V., Lloyd,C., Lynch,T., Ma,R., Pabbaraju,K., Rotich,S., Sergeant,H., Skitsko,T., Tipples,G., Thayer,J., Shideler,S., Wong,A.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Haidl,E., Chapel,M., Tyler,A.D., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Kaplen,B., Antonation,K., Laminman,V., Jolly,G., Croxen,M., Deo,A., Dieu,P., Dong,X., Gill,K., Granger,D., Ferrato,C., Ikkurti,V., Kanji,J., Koleva,P., Li,V., Lloyd,C., Lynch,T., Ma,R., Pabbaraju,K., Rotich,S., Sergeant,H., Skitsko,T., Tipples,G., Thayer,J., Shideler,S., Wong,A." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3440/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP586622" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-06" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G52914A", - "C73424T" - ] - } - } - }, - { - "name": "MPXV_USA_2022_IL0006", - "node_attrs": { - "div": 6, - "author": { - "author": "Gigante,C., Ghinai,I., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Kerins,J., Li,Y.", - "value": "Gigante,C., Ghinai,I., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Kerins,J., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_IL0006" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ427147" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G131810A", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG151": [ - "D963N" - ] - }, - "labels": { - "aa": "OPG151: D963N" - } - } - }, - { - "name": "NODE_0000093", - "node_attrs": { - "div": 7, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G45236A", - "G174962A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG204": [ - "R144K" - ] - }, - "labels": { - "aa": "OPG204: R144K" - } - }, - "children": [ - { - "name": "MPX_J6xzTO_9000286", - "node_attrs": { - "div": 7, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_J6xzTO_9000286" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415246" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPX_J6xzTO_9000287", - "node_attrs": { - "div": 8, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_J6xzTO_9000287" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415247" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C81418T" - ], - "OPG105": [ - "S98L" - ] - }, - "labels": { - "aa": "OPG105: S98L" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000094", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G36259A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G174543A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI496", - "node_attrs": { - "div": 6, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI496" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP626135" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C40251T", - "C154472T", - "G167517A", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179154C", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG058": [ - "D62N" - ], - "OPG181": [ - "H21Y" - ], - "OPG193": [ - "E62K" - ] - }, - "labels": { - "aa": "OPG058: D62N; OPG181: H21Y; OPG193: E62K" - } - } - }, - { - "name": "MPX/Human/USA/CA-LACPHL-MA00247/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPX/Human/USA/CA-LACPHL-MA00247/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP722506" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-16" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "hMpxV/USA/CA-CDPH-1000062/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., Bell,J., Hacker,J." - }, - "strain_original": { - "value": "hMpxV/USA/CA-CDPH-1000062/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ121016" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-29" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A196448-", - "A196449-", - "A196450-" - ] - } - } - }, - { - "name": "NODE_0000095", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C177720T", - "-196603A" - ], - "OPG205": [ - "R689C" - ] - }, - "labels": { - "aa": "OPG205: R689C" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-108160/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-108160/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503748" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-XX" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A80755C", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G159203A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179154C", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG104": [ - "C89G" - ], - "OPG185": [ - "G96E" - ] - }, - "labels": { - "aa": "OPG104: C89G; OPG185: G96E" - } - } - }, - { - "name": "hMpxV/USA/CACDPH1MPX1000185/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J." - }, - "strain_original": { - "value": "hMpxV/USA/CACDPH1MPX1000185/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ547900" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-12-21" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T6975-", - "G92733A" - ], - "OPG113": [ - "E335K" - ] - }, - "labels": { - "aa": "OPG113: E335K" - } - } - } - ] - }, - { - "name": "NODE_0000096", - "node_attrs": { - "div": 5, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C25967T", - "C172792T" - ], - "OPG042": [ - "W377*" - ] - }, - "labels": { - "aa": "OPG042: W377*" - } - }, - "children": [ - { - "name": "NODE_0000097", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T463-", - "G464-", - "G465-", - "A163469T" - ], - "OPG189": [ - "E46V" - ] - }, - "labels": { - "aa": "OPG189: E46V" - } - }, - "children": [ - { - "name": "MPX/Human/USA/CA-LACPHL-MA00117/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPX/Human/USA/CA-LACPHL-MA00117/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP539902" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-22" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000098", - "node_attrs": { - "div": 14, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G70435A", - "C125412T", - "C141442T", - "C141511T", - "G158709A", - "T172792C", - "G175698A", - "G176439A", - "A196563-", - "C196564-", - "T196565-" - ], - "OPG145": [ - "S489L" - ], - "OPG161": [ - "S114L", - "S137F" - ], - "OPG205": [ - "D15N", - "D262N" - ] - }, - "labels": { - "aa": "OPG145: S489L; OPG161: S114L, S137F; OPG205: D15N, D262N" - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00452/2022", - "node_attrs": { - "div": 14, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00452/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503786" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-12" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00434/2022", - "node_attrs": { - "div": 14, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00434/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503808" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-28" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000099", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G542-", - "A543-", - "G544-", - "C97805T" - ], - "OPG117": [ - "P586L" - ] - }, - "labels": { - "aa": "OPG117: P586L" - } - }, - "children": [ - { - "name": "Monkeypox virus/Human/USA/CA-LACPHL-MA00268/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "Monkeypox virus/Human/USA/CA-LACPHL-MA00268/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP748954" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-30" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00343/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00343/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP920681" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-10" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T495-", - "A496-", - "T497-" - ] - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00469/2022", - "node_attrs": { - "div": 8, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00469/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ644775" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-18" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C100640T", - "C105632T" - ], - "OPG124": [ - "E113K" - ] - }, - "labels": { - "aa": "OPG124: E113K" - } - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000100", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G1302A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150565G", - "-150566A", - "-150567T", - "C182950T" - ], - "OPG210": [ - "S532L" - ] - }, - "labels": { - "aa": "OPG210: S532L", - "clade": "B.1.12" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/ON/RKI866", - "node_attrs": { - "div": 1, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI866" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773485" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-" - ] - } - } - }, - { - "name": "NODE_0000101", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G78328A", - "C195908T" - ], - "OPG001": [ - "L92F" - ] - }, - "labels": { - "aa": "OPG001: L92F" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI399", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI399" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP524001" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T" - ] - } - } - }, - { - "name": "NODE_0000102", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C57550T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150565-", - "A150566-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - }, - "children": [ - { - "name": "MPX_BhVKjm_9000232", - "node_attrs": { - "div": 3, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_BhVKjm_9000232" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415206" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPX_BhVKjm_9000233", - "node_attrs": { - "div": 3, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_BhVKjm_9000233" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415207" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000103", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A1302G", - "G111084A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150565-", - "A150566-", - "T150567-" - ] - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-3448/2022", - "node_attrs": { - "div": 2, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3448/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880548" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-03" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3342/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3342/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880540" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-01" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G121510A" - ] - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3276/2022", - "node_attrs": { - "div": 2, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Chapel,M., Tyler,A., Haidl,E., Domselaar,G.V., Antonation,K., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Jolly,G., Fafard,J., Charest,H., Levade,I.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Chapel,M., Tyler,A., Haidl,E., Domselaar,G.V., Antonation,K., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Jolly,G., Fafard,J., Charest,H., Levade,I." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3276/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP013003" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-31" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179015-", - "A179016-", - "T179017-", - "T179018-", - "T179019-", - "G179020-", - "T179021-", - "C179022-", - "G179023-", - "A179024-", - "G179025-", - "T179026-", - "A179027-", - "T179028-", - "G179029-", - "A179030-", - "A179031-", - "T179032-", - "A179033-", - "C179034-", - "G179035-", - "G179036-", - "A179037-", - "G179038-", - "T179039-", - "A179040-", - "C179041-", - "A179042-", - "A179043-", - "A179044-", - "C179045-", - "A179046-", - "T179047-", - "A179048-", - "A179049-", - "A179050-", - "C179051-", - "T179052-", - "G179053-", - "A179054-", - "A179055-", - "G179056-", - "T179057-", - "T179058-", - "T179059-", - "A179060-", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-" - ] - } - } - }, - { - "name": "hMpxV/Human/USA/IL-RIPHL-MPXV_10015/2022", - "node_attrs": { - "div": 10, - "author": { - "author": "Barbian,H., Green,S., Kunstman,K., Araujo Perez,F., Bobrovska,S., Hayden,M., Moore,N.", - "value": "Barbian,H., Green,S., Kunstman,K., Araujo Perez,F., Bobrovska,S., Hayden,M., Moore,N." - }, - "strain_original": { - "value": "hMpxV/Human/USA/IL-RIPHL-MPXV_10015/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ121959" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-18" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G4859A", - "C24077T", - "C24231T", - "G67582A", - "C88319T", - "G97405A", - "C101656T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "G165506A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "C192351T", - "A196604-" - ], - "NBT03_gp175": [ - "S433L" - ], - "OPG015": [ - "S433L" - ], - "OPG085": [ - "S317L" - ], - "OPG109": [ - "A377T" - ], - "OPG117": [ - "E453K" - ], - "OPG190": [ - "E129K" - ] - }, - "labels": { - "aa": "NBT03_gp175: S433L; OPG015: S433L; OPG085: S317L; OPG109: A377T; OPG117: E453K; OPG190: E129K" - } - } - }, - { - "name": "NODE_0000104", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G98233A", - "G98455A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG117": [ - "D729N" - ], - "OPG118": [ - "G4R" - ] - }, - "labels": { - "aa": "OPG117: D729N; OPG118: G4R" - } - }, - "children": [ - { - "name": "MPX/BR0002/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Coletti,T.M., Ghilardi,F., khan,M.J., Claro,I.M., Valenca,I.N., Faria,N.R., Sabino,E.C.", - "value": "Coletti,T.M., Ghilardi,F., khan,M.J., Claro,I.M., Valenca,I.N., Faria,N.R., Sabino,E.C." - }, - "strain_original": { - "value": "MPX/BR0002/2022" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Imperial College London, School of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880413" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Brazil" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-14" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C76334T", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "G173165-", - "C173166-", - "G173167-", - "G173168-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-" - ], - "OPG097": [ - "R181K" - ] - }, - "labels": { - "aa": "OPG097: R181K" - } - } - }, - { - "name": "NODE_0000105", - "node_attrs": { - "div": 5, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G98456A" - ], - "OPG118": [ - "R4K" - ] - }, - "labels": { - "aa": "OPG118: R4K" - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-3972/2022", - "node_attrs": { - "div": 8, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Griffiths,E., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Griffiths,E., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3972/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP270022" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-04" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G3361A", - "C152970T", - "G181349A", - "C193849T" - ], - "OPG003": [ - "S416L" - ] - }, - "labels": { - "aa": "OPG003: S416L" - } - } - }, - { - "name": "NY-NYCPHL-001033", - "node_attrs": { - "div": 5, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-001033" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468564" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-30" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "T133079-", - "-150551G", - "-150552A", - "-150553T" - ] - } - } - }, - { - "name": "NY-NYCPHL-000223", - "node_attrs": { - "div": 5, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000223" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469055" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-03" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "NY-NYCPHL-000054", - "node_attrs": { - "div": 6, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000054" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ504387" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-04" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A136513-", - "T136514-", - "C136515-", - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G166395A" - ], - "OPG153": [ - "D385-" - ], - "OPG191": [ - "E79K" - ] - }, - "labels": { - "aa": "OPG153: D385-; OPG191: E79K" - } - } - }, - { - "name": "MPXV_USA_2022_TN0019", - "node_attrs": { - "div": 8, - "author": { - "author": "Gigante,C., Thomas,L., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Dunn,J., Li,Y.", - "value": "Gigante,C., Thomas,L., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Dunn,J., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_TN0019" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR209309" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-12-XX" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C93601T", - "C94418T", - "T133078-", - "T133079-", - "C136029T" - ], - "OPG113": [ - "A624V" - ], - "OPG114": [ - "E84K" - ] - }, - "labels": { - "aa": "OPG113: A624V; OPG114: E84K" - } - } - }, - { - "name": "NODE_0000106", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C24231T" - ] - } - }, - "children": [ - { - "name": "hMPXV-IHU00008", - "node_attrs": { - "div": 7, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "strain_original": { - "value": "hMPXV-IHU00008" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP382485" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-05" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T591-", - "A592-", - "-594T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "G184227A" - ], - "OPG210": [ - "D958N" - ] - }, - "labels": { - "aa": "OPG210: D958N" - } - } - }, - { - "name": "BOL-UNIMOL-MPX-293015-L", - "node_attrs": { - "div": 6, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "strain_original": { - "value": "BOL-UNIMOL-MPX-293015-L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP390179" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-24" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "MPX_ilzdZn_9000269", - "node_attrs": { - "div": 7, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_ilzdZn_9000269" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415236" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G23457A", - "A178020-", - "T178021-", - "A178022-", - "A178023-", - "T178024-", - "G178025-", - "A178026-", - "A178027-", - "T178028-", - "A178029-", - "C178030-", - "A178031-", - "C178032-", - "A178033-", - "T178034-", - "A178035-", - "C178036-", - "A178037-" - ], - "OPG039": [ - "S221F" - ] - }, - "labels": { - "aa": "OPG039: S221F" - } - } - }, - { - "name": "NY-NYCPHL-000623", - "node_attrs": { - "div": 13, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000623" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468719" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-23" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G19242A", - "C40254T", - "G57530A", - "C91294T", - "G98464A", - "C120617T", - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C174967T" - ], - "OPG058": [ - "A61T" - ], - "OPG076": [ - "S34L" - ], - "OPG118": [ - "D7N" - ], - "OPG138": [ - "M172I" - ], - "OPG204": [ - "H146Y" - ] - }, - "labels": { - "aa": "OPG058: A61T; OPG076: S34L; OPG118: D7N; OPG138: M172I; OPG204: H146Y" - } - } - }, - { - "name": "NODE_0000107", - "node_attrs": { - "div": 7, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G61102A" - ], - "OPG080": [ - "S306F" - ] - }, - "labels": { - "aa": "OPG080: S306F" - } - }, - "children": [ - { - "name": "MPXV/UZ_REGA_214/Belgium/2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_214/Belgium/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR095032" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-08" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/UZ_REGA_215/Belgium/2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_215/Belgium/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR095033" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-08" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000108", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G153910A" - ], - "OPG180": [ - "E407K" - ] - }, - "labels": { - "aa": "OPG180: E407K" - } - }, - "children": [ - { - "name": "NY-NYCPHL-000612", - "node_attrs": { - "div": 7, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000612" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ419047" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-10" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G57466-", - "G57467-", - "C57468-", - "C57469-", - "A57470-", - "A57471-", - "C57472-", - "C57473-", - "T57474-", - "T57475-", - "T57476-", - "G57477-", - "T57478-", - "T57479-", - "G57480-", - "T57481-", - "A57482-", - "C57483-", - "A57484-", - "A57485-", - "A57486-", - "T57487-", - "T57488-", - "C57489-", - "C57490-", - "T57491-", - "C57492-", - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G164002A" - ], - "OPG075": [ - "E3-", - "E4-", - "F5-", - "V6-", - "Q7-", - "Q8-", - "R9-", - "L10-", - "A11-" - ], - "OPG189": [ - "D224N" - ] - }, - "labels": { - "aa": "OPG075: E3-, E4-, F5-, V6-, Q7-, Q8-, R9-, L10-, A11-; OPG189: D224N" - } - } - }, - { - "name": "NY-NYCPHL-001097", - "node_attrs": { - "div": 7, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-001097" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468578" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-06" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G182189A" - ] - } - } - }, - { - "name": "NY-NYCPHL-000405", - "node_attrs": { - "div": 8, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000405" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468980" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-24" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C173016T", - "C180561T" - ], - "OPG209": [ - "S15L" - ] - }, - "labels": { - "aa": "OPG209: S15L" - } - } - }, - { - "name": "NODE_0000109", - "node_attrs": { - "div": 7, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G28483A" - ] - } - }, - "children": [ - { - "name": "MPXV_USA_2022_UT0007", - "node_attrs": { - "div": 11, - "author": { - "author": "Gigante,C., Murray,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Knipe,K., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Atkinson,A., Li,Y.", - "value": "Gigante,C., Murray,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Knipe,K., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Atkinson,A., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_UT0007" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ427129" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C15582T", - "C48299T", - "C122936T", - "G170349A", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-" - ], - "OPG143": [ - "R127Q" - ] - }, - "labels": { - "aa": "OPG143: R127Q" - } - } - }, - { - "name": "NODE_0000110", - "node_attrs": { - "div": 8, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C21910T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG037": [ - "R175K" - ] - }, - "labels": { - "aa": "OPG037: R175K" - } - }, - "children": [ - { - "name": "NY-NYCPHL-001187", - "node_attrs": { - "div": 8, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-001187" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ419087" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-01-05" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150577-", - "A150578-", - "T150579-", - "A150580-", - "T150581-", - "G150582-", - "A150583-", - "T150584-" - ] - } - } - }, - { - "name": "NY-NYCPHL-001188", - "node_attrs": { - "div": 10, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-001188" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ419088" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-01-05" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C47537T", - "C104712T", - "T150587-", - "A150588-", - "T150589-", - "G150590-" - ], - "OPG123": [ - "R120K" - ] - }, - "labels": { - "aa": "OPG123: R120K" - } - } - }, - { - "name": "NY-NYCPHL-000630", - "node_attrs": { - "div": 11, - "author": { - "author": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000630" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468615" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-04" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A76036T", - "C165073T", - "C168386T" - ], - "OPG195": [ - "H53Y" - ] - }, - "labels": { - "aa": "OPG195: H53Y" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00490/2023", - "node_attrs": { - "div": 11, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00490/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ918701" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-02-10" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G39552A", - "T57420-", - "A57421-", - "C57422-", - "A57423-", - "A57424-", - "A57425-", - "A57426-", - "A57427-", - "G57428-", - "G57429-", - "A57430-", - "C57431-", - "A57432-", - "T57433-", - "G57434-", - "T57435-", - "A57436-", - "A57437-", - "A57438-", - "C57439-", - "T57440-", - "G132490A", - "C150443T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-" - ], - "OPG057": [ - "S215F" - ], - "OPG075": [ - "K20X", - "F21-", - "T22-", - "C23-", - "P24-", - "F25-", - "C26-", - "R27X", - "*109X" - ], - "OPG176": [ - "T212I" - ] - }, - "labels": { - "aa": "OPG057: S215F; OPG075: K20X, F21-, T22-, C23-, P24-, F25-, C26-, R27X, *109X; OPG176: T212I" - } - } - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000111", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G36617A", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150565G", - "-150566A", - "-150567T", - "C159779T" - ], - "OPG055": [ - "S156L" - ], - "OPG185": [ - "S288L" - ] - }, - "labels": { - "aa": "OPG055: S156L; OPG185: S288L", - "clade": "B.1.14" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI011", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI011" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON694342" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150564T", - "A192404-", - "G192405-", - "T192406-", - "C192407-", - "A192408-", - "T192409-", - "A192410-", - "A192411-", - "G192412-", - "T192413-", - "T192414-", - "A192415-", - "G192416-", - "T192417-", - "T192418-", - "A192419-", - "A192420-", - "G192421-", - "T192422-", - "C192423-", - "A192424-", - "T192425-", - "A192426-", - "A192427-", - "G192428-", - "T192429-", - "T192430-", - "A192431-", - "G192432-", - "T192433-", - "T192434-", - "A192435-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI082", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI082" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON853664" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150564T" - ] - } - } - }, - { - "name": "MPXV_USA_2022_NY002", - "node_attrs": { - "div": 2, - "author": { - "author": "Gigante,C.M., Hughes,S., Seabolt,M.H., Zhao,H., Wilkins,K., Respress,J., Howard,D., Batra,D., McCollum,A., Hutson,C., Davidson,W., Rao,A., Baumgartner,J., Li,Y.", - "value": "Gigante,C.M., Hughes,S., Seabolt,M.H., Zhao,H., Wilkins,K., Respress,J., Howard,D., Batra,D., McCollum,A., Hutson,C., Davidson,W., Rao,A., Baumgartner,J., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_NY002" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON959133" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "G150565-", - "A150566-", - "T150567-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A196604-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI155", - "node_attrs": { - "div": 4, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI155" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON959169" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150564T", - "G168365A", - "G170929A" - ], - "OPG195": [ - "E46K" - ] - }, - "labels": { - "aa": "OPG195: E46K" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI302", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI302" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP355563" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150564T", - "A188349-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI668", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI668" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ274887" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "A152668-", - "T152680-" - ] - } - } - }, - { - "name": "NY-NYCPHL-000273", - "node_attrs": { - "div": 2, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000273" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468471" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-01" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "G150565-", - "A150566-", - "T150567-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "NY-NYCPHL-001084", - "node_attrs": { - "div": 2, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-001084" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469263" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-05" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150564T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "NY-NYCPHL-000043", - "node_attrs": { - "div": 2, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000043" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ504383" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-25" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150564T", - "A150566-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI725", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI725" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ547752" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C3837T", - "G150550-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "G181049-" - ], - "OPG209": [ - "G178X", - "*191X" - ] - }, - "labels": { - "aa": "OPG209: G178X, *191X" - } - } - }, - { - "name": "Lesion", - "node_attrs": { - "div": 4, - "author": { - "author": "Pettke,A., Filen,F., Asgeirsson,H., Glans,H., Widgren,K., Muradrasoli,S., Helgesson,S., Karlberg,M.L., Walai,N., Bjerkner,A., Gourle,H., Lindsjo,O.K., Sonden,K.", - "value": "Pettke,A., Filen,F., Asgeirsson,H., Glans,H., Widgren,K., Muradrasoli,S., Helgesson,S., Karlberg,M.L., Walai,N., Bjerkner,A., Gourle,H., Lindsjo,O.K., Sonden,K." - }, - "strain_original": { - "value": "Lesion" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Public Health Agency of Sweden, Unit for Laboratory Development and Technology Transfer , Folkhalsomyndigheten, 171 82 Solna" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OX009124" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Sweden" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-22" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "T597-", - "T598-", - "T599-", - "T600-", - "A8048-", - "A28524-", - "A28525-", - "T47051-", - "T76079-", - "T88831-", - "A91698-", - "A92904-", - "T103362-", - "T104686-", - "T148344A", - "A148345T", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "G150565-", - "A150566-", - "T150567-", - "A151674-", - "A162901-", - "T163338-", - "T163592-", - "A170723-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A196604-" - ], - "OPG044": [ - "E145X", - "*150X" - ], - "OPG066": [ - "K126X", - "*260X" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG109": [ - "K206X", - "*796X" - ], - "OPG113": [ - "K392X", - "*846X" - ], - "OPG123": [ - "T129X", - "N570X", - "*632X" - ], - "OPG178": [ - "K56X", - "*205X" - ], - "OPG188": [ - "K436X", - "*504X" - ], - "OPG189": [ - "D2X", - "I87X", - "*562X" - ], - "OPG198": [ - "Q229X", - "*283X" - ] - }, - "labels": { - "aa": "OPG044: E145X, *150X; OPG066: K126X, *260X; OPG097: K266X, *345X; OPG109: K206X, *796X; OPG113: K392X, *846X; OPG123: T129X, N570X, *632X; OPG178: K56X, *205X; OPG188: K436X, *504X; OPG189: D2X, I87X, *562X; OPG198: Q229X, *283X" - } - } - }, - { - "name": "NODE_0000112", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C84008T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150564T" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/ON/RKI314", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI314" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP355572" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A188349-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI589", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI589" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP837351" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000113", - "node_attrs": { - "div": 5, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C8552T", - "C8597T", - "G46179A", - "A150561-", - "T150562-", - "A150563-", - "A150566-", - "T150567-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "A179164-", - "T179165-", - "T179166-" - ], - "OPG065": [ - "S102L" - ] - }, - "labels": { - "aa": "OPG065: S102L" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_TX0010", - "node_attrs": { - "div": 5, - "author": { - "author": "Gigante,C.M., Kubin,G., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S.L., Li,Y.", - "value": "Gigante,C.M., Kubin,G., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S.L., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_TX0010" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP378704" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "-595T", - "G150559-", - "G150560-", - "G150565-", - "C179154-", - "C179163-", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI346", - "node_attrs": { - "div": 7, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI346" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP484667" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C45361T", - "C133557T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T" - ], - "OPG064": [ - "D180N" - ] - }, - "labels": { - "aa": "OPG064: D180N" - } - } - } - ] - }, - { - "name": "NODE_0000114", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G158617A", - "C183790T" - ], - "OPG210": [ - "S812L" - ] - }, - "labels": { - "aa": "OPG210: S812L" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI102", - "node_attrs": { - "div": 6, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI102" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON929060" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C127245T", - "C132437T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150564T" - ], - "OPG149": [ - "S17L" - ] - }, - "labels": { - "aa": "OPG149: S17L" - } - } - }, - { - "name": "NODE_0000115", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C22880T", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "G150565-", - "A150566-", - "T150567-", - "C170573T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG038": [ - "E94K" - ], - "OPG198": [ - "S179L" - ] - }, - "labels": { - "aa": "OPG038: E94K; OPG198: S179L" - } - }, - "children": [ - { - "name": "MPXV/UZ_REGA_40", - "node_attrs": { - "div": 6, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_40" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035646" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-27" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/UZ_REGA_147/Belgium/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_147/Belgium/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR086956" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-05" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T149487-", - "A149488-", - "C149489-", - "G149490-", - "T149491-", - "T149492-", - "G149493-", - "A149494-", - "A149495-", - "C149496-", - "A149497-", - "A149498-", - "G149499-", - "T149500-", - "C149501-", - "C149502-", - "A149503-" - ], - "OPG175": [ - "Y16-", - "V17-", - "E18-", - "Q19-", - "V20-", - "H21X", - "*126X" - ] - }, - "labels": { - "aa": "OPG175: Y16-, V17-, E18-, Q19-, V20-, H21X, *126X" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000116", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G28021A" - ] - } - }, - "children": [ - { - "name": "MPX/Human/USA/CA-LACPHL-MA00137/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPX/Human/USA/CA-LACPHL-MA00137/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP539922" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-09" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G109793A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150564T", - "G168211-", - "G168212-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "G181818A" - ], - "OPG210": [ - "A155T" - ] - }, - "labels": { - "aa": "OPG210: A155T" - } - } - }, - { - "name": "NODE_0000117", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C148666T", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "G150565-", - "A150566-", - "T150567-" - ], - "OPG174": [ - "A244T" - ] - }, - "labels": { - "aa": "OPG174: A244T" - } - }, - "children": [ - { - "name": "MPXV/Human/USA/UT-UPHL-82200381/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Iverson,T., Oakeson,K.F., Young,E.L., Wagner,J., Hergert,J.", - "value": "Iverson,T., Oakeson,K.F., Young,E.L., Wagner,J., Hergert,J." - }, - "strain_original": { - "value": "MPXV/Human/USA/UT-UPHL-82200381/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Utah Public Health Laboratory, Utah Public Health Laboratory Infectious Disease submission group" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR026628" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-10" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Human/USA/UT-UPHL-82200382/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Iverson,T., Oakeson,K.F., Young,E.L., Wagner,J., Hergert,J.", - "value": "Iverson,T., Oakeson,K.F., Young,E.L., Wagner,J., Hergert,J." - }, - "strain_original": { - "value": "MPXV/Human/USA/UT-UPHL-82200382/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Utah Public Health Laboratory, Utah Public Health Laboratory Infectious Disease submission group" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR026629" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-09" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000118", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "-150564T", - "G171270A", - "-196603A" - ], - "OPG199": [ - "D95N" - ] - }, - "labels": { - "aa": "OPG199: D95N" - } - }, - "children": [ - { - "name": "hMPXV-IHU00015", - "node_attrs": { - "div": 4, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "strain_original": { - "value": "hMPXV-IHU00015" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP382492" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-22" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G161913A", - "A178998-", - "T178999-", - "T179000-", - "G179001-", - "T179002-", - "G179003-", - "T179004-", - "A179005-", - "C179006-", - "A179007-", - "C179008-", - "G179009-", - "A179010-", - "T179011-", - "A179012-", - "C179013-", - "C179014-", - "A179015-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "T196584-", - "C196585-", - "A196586-" - ] - } - } - }, - { - "name": "hMPXV-IHU00016", - "node_attrs": { - "div": 6, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "strain_original": { - "value": "hMPXV-IHU00016" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP382493" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-22" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G25999A", - "G97417A", - "G100939A", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "C179045-", - "A179046-", - "T179047-", - "A179048-", - "A179049-", - "A179050-", - "C179051-", - "T179052-", - "G179053-", - "A179054-", - "A179055-", - "G179056-", - "T179057-", - "T179058-", - "T179059-", - "A179060-", - "A179061-", - "C179062-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A196603-" - ], - "OPG042": [ - "Q367*" - ], - "OPG117": [ - "E457K" - ] - }, - "labels": { - "aa": "OPG042: Q367*; OPG117: E457K" - } - } - }, - { - "name": "Monkeypox/PT0486/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0486/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555562" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-09" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T" - ] - } - } - }, - { - "name": "Monkeypox/PT0501/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0501/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555575" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-16" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T" - ] - } - } - }, - { - "name": "Monkeypox/PT0573/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0573/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555644" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-06" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594A", - "-595T", - "-596T", - "C93713T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "G158549A", - "-196601A", - "-196602A", - "A196616T" - ] - } - } - }, - { - "name": "Slovenia-MPXV-10-2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "strain_original": { - "value": "Slovenia-MPXV-10-2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605553" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594A", - "-595T", - "-596T", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G196443-", - "A196444-", - "A196445-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI507", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI507" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP689660" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T597-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T" - ] - } - } - }, - { - "name": "NY-NYCPHL-001139", - "node_attrs": { - "div": 3, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-001139" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468597" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-06" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000128", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C89906T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG110": [ - "S92F" - ] - }, - "labels": { - "aa": "OPG110: S92F" - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-30513C", - "node_attrs": { - "div": 7, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-30513C" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ696098" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-10" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A577-", - "A578-", - "A579-", - "G32863A", - "G45416A", - "C67823T", - "C72770T", - "C123118T", - "C148771T", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-", - "A196376-", - "T196377-", - "C196378-" - ], - "OPG085": [ - "E237K" - ], - "OPG092": [ - "E60K" - ], - "OPG174": [ - "D209N" - ] - }, - "labels": { - "aa": "OPG085: E237K; OPG092: E60K; OPG174: D209N" - } - } - }, - { - "name": "NODE_0000186", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G94798A" - ], - "OPG115": [ - "E47K" - ] - }, - "labels": { - "aa": "OPG115: E47K", - "clade": "B.1.10" - } - }, - "children": [ - { - "name": "MPXV_UK_2022_9000147", - "node_attrs": { - "div": 2, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPXV_UK_2022_9000147" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205110" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-14" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV_USA_2022_TX0019", - "node_attrs": { - "div": 2, - "author": { - "author": "Gigante,C.M., Kubin,G., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S.L., Li,Y.", - "value": "Gigante,C.M., Kubin,G., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S.L., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_TX0019" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP450985" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "A136513-", - "T136514-", - "C136515-", - "-196603A" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI362", - "node_attrs": { - "div": 4, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI362" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP484683" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C17027T", - "C84943T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ], - "OPG029": [ - "D15N" - ], - "OPG105": [ - "S1273F" - ] - }, - "labels": { - "aa": "OPG029: D15N; OPG105: S1273F" - } - } - }, - { - "name": "MpxV/Spain/MD-HGUGM-6513479/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Buenestado-Serrano,S., Palomino-Cabrera,R., Penas-Utrilla,D., Rodriguez-Grande,J., Sola Campoy,P., Perez-Lago,L., Rodriguez-Grande,C., Herranz Martin,M., Suarez,J., Catalan,P., Munoz,P., Garcia de Viedma,D.", - "value": "Buenestado-Serrano,S., Palomino-Cabrera,R., Penas-Utrilla,D., Rodriguez-Grande,J., Sola Campoy,P., Perez-Lago,L., Rodriguez-Grande,C., Herranz Martin,M., Suarez,J., Catalan,P., Munoz,P., Garcia de Viedma,D." - }, - "strain_original": { - "value": "MpxV/Spain/MD-HGUGM-6513479/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Microbial Genomics, Hospital General Universitario Gregorio Marañón, Madrid, Spain" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON720848" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-27" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A322-", - "T596-", - "T597-", - "A1691-", - "T4293-", - "T6583-", - "T6584-", - "T7248-", - "G7723-", - "T8011-", - "A8032-", - "T8494-", - "T9508-", - "A9864-", - "T10497-", - "A10908-", - "T11184-", - "C11751-", - "T11752-", - "C11754T", - "T11756C", - "T12121-", - "A15754-", - "A17083-", - "T18861-", - "A19353-", - "T20660-", - "A21075-", - "T21971-", - "T24677-", - "T25851-", - "T26098-", - "C27001-", - "A27108-", - "C27798-", - "A28524-", - "A28525-", - "T32188-", - "T33409-", - "G35948-", - "T37976-", - "T39127-", - "T39861-", - "T41738-", - "T42989-", - "C43012-", - "G43199-", - "A43442-", - "T44116-", - "T44735-", - "G46761-", - "T48670-", - "A49130-", - "T49830-", - "A51019-", - "A52765-", - "A54964-", - "A55119-", - "T55557-", - "T56035-", - "T57069-", - "A57274-", - "A58644-", - "T61743-", - "A62034-", - "T63624-", - "A64726-", - "A64931-", - "A65531-", - "A65962-", - "T66777-", - "A66839-", - "A67161-", - "C68464-", - "T68479-", - "C68898-", - "G69145-", - "A69739-", - "G69767-", - "A71250-", - "G71358-", - "T75828-", - "A76072-", - "T76079-", - "T76080-", - "A76150-", - "A76151-", - "A76883-", - "A77254-", - "T77800-", - "T78059-", - "A79037-", - "A79177-", - "G79217-", - "C79533T", - "A79782-", - "G80949-", - "C82480-", - "T84843-", - "T88090-", - "T88831-", - "T88939-", - "A89100-", - "T90643-", - "T91125-", - "T91365-", - "A91579-", - "A91698-", - "T94789-", - "A95338-", - "A95573-", - "G95742-", - "G95818-", - "A97348-", - "A97477-", - "A97496-", - "A97695-", - "A98679-", - "T101449-", - "G101515-", - "T102434-", - "T103362-", - "T103363-", - "T104274-", - "T105355-", - "T106591-", - "T108593-", - "A113916-", - "T113946-", - "C114428-", - "T114514-", - "T114751-", - "T115122-", - "G115798-", - "A116008-", - "C116494-", - "T116958-", - "T121116-", - "T121117-", - "G121268-", - "C121544-", - "T124020-", - "T124747-", - "A125246-", - "A126564-", - "T126680-", - "A126711-", - "A127246-", - "A127747-", - "A132020-", - "A132021-", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "T133084-", - "T133085-", - "T133633-", - "T136777-", - "T137881-", - "A143045-", - "A143360-", - "T143474-", - "A144224-", - "T146127-", - "A147994-", - "A149723-", - "A150337-", - "T150532-", - "T150533-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G150577-", - "A150578-", - "T150579-", - "A150580-", - "T150581-", - "G150582-", - "A150583-", - "T150584-", - "G150620-", - "G150621-", - "A150622-", - "T150623-", - "A150624-", - "T150625-", - "G150626-", - "A150627-", - "T150628-", - "A150629-", - "T150859-", - "A151485-", - "A151506-", - "G151544-", - "A152668-", - "T152680-", - "A153355-", - "A153418-", - "A153514-", - "T154859-", - "T155417-", - "C156605-", - "C156606-", - "A157991-", - "T163494-", - "T163592-", - "A163954-", - "A165456-", - "A166737-", - "G167640-", - "A167964-", - "T168116-", - "A170723-", - "T170754-", - "T170897-", - "T170898-", - "T172079-", - "T172661-", - "G179035-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-", - "-179085T", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091T", - "-179092A", - "-179093T", - "-179094T", - "A179546-", - "A179945-", - "T180901-", - "G181049-", - "A181246-", - "C183531-", - "A183777-", - "T187073-", - "A190929-", - "A191010-", - "G191517-", - "A196604-", - "A196605-", - "T196883-", - "T197177-" - ], - "NBT03_gp052": [ - "L8X", - "Y60X", - "*130X" - ], - "NBT03_gp174": [ - "K174X", - "*177X" - ], - "NBT03_gp175": [ - "R155X", - "*438X" - ], - "OPG019": [ - "E48X", - "*143X" - ], - "OPG021": [ - "Q93X", - "*243X" - ], - "OPG022": [ - "K121X", - "*127X" - ], - "OPG023": [ - "I260X", - "K382R", - "E383X", - "G384X", - "I573X", - "*661X" - ], - "OPG036": [ - "K135X", - "*178X" - ], - "OPG037": [ - "I155X", - "*443X" - ], - "OPG040": [ - "M268X", - "*376X" - ], - "OPG042": [ - "E33X", - "T334X", - "K416X", - "*425X" - ], - "OPG043": [ - "G53X", - "*277X" - ], - "OPG044": [ - "E145X", - "*150X" - ], - "OPG054": [ - "H17X", - "*440X" - ], - "OPG056": [ - "K353X", - "*636X" - ], - "OPG057": [ - "N112X", - "I357X", - "*373X" - ], - "OPG061": [ - "K49X", - "*232X" - ], - "OPG063": [ - "S83X", - "L164X", - "G226X", - "I234X", - "*480X" - ], - "OPG064": [ - "K388X", - "I595X", - "*738X" - ], - "OPG066": [ - "P223X", - "*260X" - ], - "OPG068": [ - "I157X", - "A310X", - "L544X", - "*568X" - ], - "OPG070": [ - "K144X", - "*274X" - ], - "OPG071": [ - "C558X", - "*1007X" - ], - "OPG074": [ - "K19X", - "N364X", - "K523X", - "*666X" - ], - "OPG075": [ - "F75X", - "*109X" - ], - "OPG078": [ - "F56X", - "*74X" - ], - "OPG080": [ - "K92X", - "*772X" - ], - "OPG083": [ - "M365X", - "*424X" - ], - "OPG084": [ - "E2X", - "G70X", - "P270X", - "E414X", - "*677X" - ], - "OPG085": [ - "K18X", - "G23X", - "F457X", - "S565X", - "K585X", - "*592X" - ], - "OPG087": [ - "F14X", - "G97X", - "*221X" - ], - "OPG088": [ - "L33X", - "L42X", - "*125X" - ], - "OPG090": [ - "R24X", - "L60X", - "*64X" - ], - "OPG096": [ - "I81X", - "*93X" - ], - "OPG097": [ - "F242X", - "K266X", - "A268X", - "*345X" - ], - "OPG098": [ - "K119X", - "*252X" - ], - "OPG099": [ - "F46X", - "*129X" - ], - "OPG100": [ - "F18X", - "*153X" - ], - "OPG102": [ - "A31X", - "G45X", - "T150I", - "E233X", - "*334X" - ], - "OPG104": [ - "P24X", - "*134X" - ], - "OPG105": [ - "A452X", - "F1240X", - "*1287X" - ], - "OPG109": [ - "F116X", - "N170X", - "K206X", - "K453X", - "*796X" - ], - "OPG111": [ - "F127X", - "N287X", - "*315X" - ], - "OPG112": [ - "I40X", - "I111X", - "*147X" - ], - "OPG115": [ - "F44X", - "K227X", - "*234X" - ], - "OPG116": [ - "P71X", - "G128X", - "S153X", - "*219X" - ], - "OPG117": [ - "K434X", - "K477X", - "E483X", - "L549X", - "*786X" - ], - "OPG118": [ - "L78X", - "*638X" - ], - "OPG120": [ - "S78X", - "K100X", - "*305X" - ], - "OPG122": [ - "F3X", - "*249X" - ], - "OPG123": [ - "K266X", - "N570X", - "*632X" - ], - "OPG124": [ - "N205X", - "*288X" - ], - "OPG125": [ - "N355X", - "*552X" - ], - "OPG127": [ - "N78X", - "*225X" - ], - "OPG133": [ - "K192X", - "I316X", - "I395X", - "G423X", - "K584X", - "F594X", - "*711X" - ], - "OPG134": [ - "G17X", - "K87X", - "P249X", - "*293X" - ], - "OPG136": [ - "N877X", - "*892X" - ], - "OPG138": [ - "N6X", - "*191X" - ], - "OPG139": [ - "P34X", - "*71X" - ], - "OPG140": [ - "G68X", - "*91X" - ], - "OPG145": [ - "L25X", - "S267X", - "K434X", - "*493X" - ], - "OPG148": [ - "P193X", - "I232X", - "G242X", - "K421X", - "*427X" - ], - "OPG149": [ - "S17X", - "I184X", - "*188X" - ], - "OPG151": [ - "K1033X", - "*1165X" - ], - "OPG153": [ - "K297X", - "*510X" - ], - "OPG154": [ - "K57X", - "*111X" - ], - "OPG164": [ - "R90X", - "S195X", - "*229X" - ], - "OPG165": [ - "K237X", - "*269X" - ], - "OPG170": [ - "I218X", - "*222X" - ], - "OPG172": [ - "K190X", - "*197X" - ], - "OPG175": [ - "S94X", - "*126X" - ], - "OPG176": [ - "K177X", - "*241X" - ], - "OPG178": [ - "L12X", - "*205X" - ], - "OPG180": [ - "K222X", - "K243X", - "K275X", - "*560X" - ], - "OPG181": [ - "F150X", - "*335X" - ], - "OPG189": [ - "D54X", - "I87X", - "K208X", - "*562X" - ], - "OPG190": [ - "E112X", - "*318X" - ], - "OPG192": [ - "K3X", - "*183X" - ], - "OPG193": [ - "G103X", - "K211X", - "T261X", - "*268X" - ], - "OPG198": [ - "Q229X", - "T239X", - "*283X" - ], - "OPG208": [ - "Q94X", - "E227X", - "*358X" - ], - "OPG209": [ - "T128X", - "G178X", - "*191X" - ], - "OPG210": [ - "P726X", - "K808X", - "*1881X" - ] - }, - "labels": { - "aa": "NBT03_gp052: L8X, Y60X, *130X; NBT03_gp174: K174X, *177X; NBT03_gp175: R155X, *438X; OPG019: E48X, *143X; OPG021: Q93X, *243X; OPG022: K121X, *127X; OPG023: I260X, K382R, E383X, G384X, I573X, *661X; OPG036: K135X, *178X; OPG037: I155X, *443X; OPG040: M268X, *376X; OPG042: E33X, T334X, K416X, *425X; OPG043: G53X, *277X; OPG044: E145X, *150X; OPG054: H17X, *440X; OPG056: K353X, *636X; OPG057: N112X, I357X, *373X; OPG061: K49X, *232X; OPG063: S83X, L164X, G226X, I234X, *480X; OPG064: K388X, I595X, *738X; OPG066: P223X, *260X; OPG068: I157X, A310X, L544X, *568X; OPG070: K144X, *274X; OPG071: C558X, *1007X; OPG074: K19X, N364X, K523X, *666X; OPG075: F75X, *109X; OPG078: F56X, *74X; OPG080: K92X, *772X; OPG083: M365X, *424X; OPG084: E2X, G70X, P270X, E414X, *677X; OPG085: K18X, G23X, F457X, S565X, K585X, *592X; OPG087: F14X, G97X, *221X; OPG088: L33X, L42X, *125X; OPG090: R24X, L60X, *64X; OPG096: I81X, *93X; OPG097: F242X, K266X, A268X, *345X; OPG098: K119X, *252X; OPG099: F46X, *129X; OPG100: F18X, *153X; OPG102: A31X, G45X, T150I, E233X, *334X; OPG104: P24X, *134X; OPG105: A452X, F1240X, *1287X; OPG109: F116X, N170X, K206X, K453X, *796X; OPG111: F127X, N287X, *315X; OPG112: I40X, I111X, *147X; OPG115: F44X, K227X, *234X; OPG116: P71X, G128X, S153X, *219X; OPG117: K434X, K477X, E483X, L549X, *786X; OPG118: L78X, *638X; OPG120: S78X, K100X, *305X; OPG122: F3X, *249X; OPG123: K266X, N570X, *632X; OPG124: N205X, *288X; OPG125: N355X, *552X; OPG127: N78X, *225X; OPG133: K192X, I316X, I395X, G423X, K584X, F594X, *711X; OPG134: G17X, K87X, P249X, *293X; OPG136: N877X, *892X; OPG138: N6X, *191X; OPG139: P34X, *71X; OPG140: G68X, *91X; OPG145: L25X, S267X, K434X, *493X; OPG148: P193X, I232X, G242X, K421X, *427X; OPG149: S17X, I184X, *188X; OPG151: K1033X, *1165X; OPG153: K297X, *510X; OPG154: K57X, *111X; OPG164: R90X, S195X, *229X; OPG165: K237X, *269X; OPG170: I218X, *222X; OPG172: K190X, *197X; OPG175: S94X, *126X; OPG176: K177X, *241X; OPG178: L12X, *205X; OPG180: K222X, K243X, K275X, *560X; OPG181: F150X, *335X; OPG189: D54X, I87X, K208X, *562X; OPG190: E112X, *318X; OPG192: K3X, *183X; OPG193: G103X, K211X, T261X, *268X; OPG198: Q229X, T239X, *283X; OPG208: Q94X, E227X, *358X; OPG209: T128X, G178X, *191X; OPG210: P726X, K808X, *1881X" - } - } - }, - { - "name": "MPXV_UK_2022_9000103", - "node_attrs": { - "div": 2, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPXV_UK_2022_9000103" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205091" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-13" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPX/PT0081/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "MPX/PT0081/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP245334" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-23" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A590-", - "T591-", - "C120237T", - "G126047A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A196599-", - "C196600-", - "-196601A", - "-196603A" - ], - "OPG148": [ - "R21K" - ] - }, - "labels": { - "aa": "OPG148: R21K" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-24446-E", - "node_attrs": { - "div": 2, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-24446-E" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP642391" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-02" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "MPXV/Spain/HUNSC_ITER_0005b/2022", - "node_attrs": { - "div": 15, - "author": { - "author": "Munoz-Barrera,A., Ciuffreda,L., Alcoba-Florez,J., Rubio-Rodriguez,L.A., Rodriguez-Perez,H., Gil-Campesino,H., Garcia-Martinez de Artola,D., Salas-Hernandez,J., Rodriguez-Nunez,J., Inigo-Campos,A., Garcia-Olivares,V., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C.", - "value": "Munoz-Barrera,A., Ciuffreda,L., Alcoba-Florez,J., Rubio-Rodriguez,L.A., Rodriguez-Perez,H., Gil-Campesino,H., Garcia-Martinez de Artola,D., Salas-Hernandez,J., Rodriguez-Nunez,J., Inigo-Campos,A., Garcia-Olivares,V., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C." - }, - "strain_original": { - "value": "MPXV/Spain/HUNSC_ITER_0005b/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ581847" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-01" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A43453G", - "A66769C", - "T88735A", - "G90070A", - "C101656T", - "G104325A", - "C121681T", - "G127869A", - "G132490A", - "T133095A", - "-133168C", - "-133169T", - "-133170T", - "-133171T", - "-133173T", - "T139779C", - "G140866T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C151204T", - "T176743A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG063": [ - "L79P" - ], - "OPG085": [ - "V588G" - ], - "OPG109": [ - "E238V" - ], - "OPG110": [ - "D147N" - ], - "OPG123": [ - "A249V" - ], - "OPG150": [ - "G31R" - ], - "OPG160": [ - "S70Y" - ], - "OPG205": [ - "L363*" - ] - }, - "labels": { - "aa": "OPG063: L79P; OPG085: V588G; OPG109: E238V; OPG110: D147N; OPG123: A249V; OPG150: G31R; OPG160: S70Y; OPG205: L363*" - } - } - }, - { - "name": "NODE_0000080", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C33103T", - "C45605T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ], - "OPG049": [ - "E17K" - ] - }, - "labels": { - "aa": "OPG049: E17K" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI241", - "node_attrs": { - "div": 5, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI241" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP215226" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G47702A" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI429", - "node_attrs": { - "div": 4, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI429" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP594193" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI885", - "node_attrs": { - "div": 4, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI885" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773504" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A41660-", - "A41661-", - "T41662-", - "T41663-", - "T41664-", - "G41665-", - "T41666-", - "T41667-", - "T41668-", - "T41669-", - "A41670-", - "C41671-", - "T41672-", - "C41673-", - "T41674-", - "A41675-", - "T41676-", - "A41677-", - "G150550-" - ], - "OPG061": [ - "Y70-", - "R71-", - "V72-", - "K73-", - "Q74-", - "I75-" - ] - }, - "labels": { - "aa": "OPG061: Y70-, R71-, V72-, K73-, Q74-, I75-" - } - } - } - ] - }, - { - "name": "NODE_0000040", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C20879T", - "C60094T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG036": [ - "M62I" - ], - "OPG080": [ - "R642K" - ] - }, - "labels": { - "aa": "OPG036: M62I; OPG080: R642K" - } - }, - "children": [ - { - "name": "MPX_Tga3e9_9000325", - "node_attrs": { - "div": 5, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_Tga3e9_9000325" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415264" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G86904A", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-" - ] - } - } - }, - { - "name": "NY-NYCPHL-000751", - "node_attrs": { - "div": 4, - "author": { - "author": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000751" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468641" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-11" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "NY-NYCPHL-000421", - "node_attrs": { - "div": 6, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000421" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468985" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-01" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C156348T", - "A182480G" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_116", - "node_attrs": { - "div": 5, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_116" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035722" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-28" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "G149818A", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG176": [ - "D4N" - ] - }, - "labels": { - "aa": "OPG176: D4N" - } - } - } - ] - }, - { - "name": "NODE_0000081", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C150831T" - ] - } - }, - "children": [ - { - "name": "MPX-96/Finland/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Kant,R., Smura,T., Vauhkonen,H., Vapalahti,O.", - "value": "Kant,R., Smura,T., Vauhkonen,H., Vapalahti,O." - }, - "strain_original": { - "value": "MPX-96/Finland/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Helsinki, Department of Virology, Faculty of Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON959143" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Finland" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-16" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "C188491T" - ] - } - } - }, - { - "name": "hMPXV-IHU00012", - "node_attrs": { - "div": 4, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "strain_original": { - "value": "hMPXV-IHU00012" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP382489" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-19" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G109437A", - "A136513-", - "T136514-", - "C136515-", - "A136516-", - "T136517-", - "C136518-", - "G150568-", - "A150569-", - "T150570-", - "A150571-", - "T150572-", - "G150573-", - "A150574-", - "T150575-", - "G150576-", - "G150577-", - "A150578-", - "T150579-", - "A150580-", - "T150581-", - "G150582-", - "A150583-", - "T150584-", - "G150585-", - "A150586-", - "T150587-", - "A150588-", - "T150589-", - "G150590-", - "A150591-", - "T150592-", - "G150593-" - ], - "OPG129": [ - "S523L" - ], - "OPG153": [ - "D384-", - "D385-" - ] - }, - "labels": { - "aa": "OPG129: S523L; OPG153: D384-, D385-" - } - } - }, - { - "name": "NY-NYCPHL-000141", - "node_attrs": { - "div": 3, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000141" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469148" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-25" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - }, - { - "name": "NY-NYCPHL-000209", - "node_attrs": { - "div": 5, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000209" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469171" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-01" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G77445A", - "G124037A", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG145": [ - "D31N" - ] - }, - "labels": { - "aa": "OPG145: D31N" - } - } - } - ] - }, - { - "name": "NODE_0000082", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G50672A", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG070": [ - "R28K" - ] - }, - "labels": { - "aa": "OPG070: R28K" - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-25342E", - "node_attrs": { - "div": 3, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-25342E" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP642414" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-04" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI511", - "node_attrs": { - "div": 5, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI511" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP689664" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-XX" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C13624T", - "C43472T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ], - "OPG063": [ - "E73K" - ] - }, - "labels": { - "aa": "OPG063: E73K" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-28206C", - "node_attrs": { - "div": 6, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-28206C" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ261697" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-13" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C15945T", - "C16362T", - "C100007T" - ], - "OPG027": [ - "E6K", - "D145N" - ], - "OPG118": [ - "S521F" - ] - }, - "labels": { - "aa": "OPG027: E6K, D145N; OPG118: S521F" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-28772C", - "node_attrs": { - "div": 3, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-28772C" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ261711" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-21" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000083", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C49265T", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-", - "-195509T", - "-195510A", - "-195511A" - ] - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-23654-O", - "node_attrs": { - "div": 7, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-23654-O" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP459217" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-30" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C113965T", - "G150800A", - "C152191T" - ], - "OPG133": [ - "E578K" - ] - }, - "labels": { - "aa": "OPG133: E578K" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-23655-L", - "node_attrs": { - "div": 4, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-23655-L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP459218" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-30" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "9000385", - "node_attrs": { - "div": 5, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "9000385" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536764" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C100007T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-178536T", - "-178537A", - "-178538T", - "-178539A", - "-178540A", - "-178541G", - "-178542C", - "-178543G", - "-178544G", - "-178545T", - "-178546C", - "-178547G", - "-178548T", - "-178549A", - "-178550C", - "-178551C", - "-178552C", - "-178553A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "A196604-" - ], - "OPG118": [ - "S521F" - ] - }, - "labels": { - "aa": "OPG118: S521F" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-26252E", - "node_attrs": { - "div": 5, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-26252E" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP881933" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-26" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G43838A" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-31875C", - "node_attrs": { - "div": 8, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-31875C" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ696105" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-24" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A208-", - "G209-", - "A210-", - "C6819T", - "G33823A", - "G38820A", - "C158040T", - "-178536T", - "-178537A", - "-178538T", - "-178539A", - "-178540A", - "-178541G", - "-178542C", - "-178543G", - "-178544G", - "-178545T", - "-178546C", - "-178547G", - "-178548T", - "-178549A", - "-178550C", - "-178551C", - "-178552C", - "-178553A" - ], - "OPG052": [ - "S58L" - ], - "OPG056": [ - "S72L" - ] - }, - "labels": { - "aa": "OPG052: S58L; OPG056: S72L" - } - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000119", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G5595A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C191615T" - ], - "NBT03_gp175": [ - "Q188*" - ], - "OPG015": [ - "Q188*" - ] - }, - "labels": { - "aa": "NBT03_gp175: Q188*; OPG015: Q188*", - "clade": "B.1.8" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI235", - "node_attrs": { - "div": 1, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI235" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP215224" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000120", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G161296A" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI177", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI177" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP018602" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Germany/2022/RKI190", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI190" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP215232" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G2039A", - "C195171T" - ], - "OPG002": [ - "S238L" - ] - }, - "labels": { - "aa": "OPG002: S238L" - } - } - }, - { - "name": "MPXV_UK_2022_9000183", - "node_attrs": { - "div": 2, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPXV_UK_2022_9000183" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP331337" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-29" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G902A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "C196308T" - ], - "OPG001": [ - "S225L" - ] - }, - "labels": { - "aa": "OPG001: S225L" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI358", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI358" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP484679" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G902A", - "C196308T" - ], - "OPG001": [ - "S225L" - ] - }, - "labels": { - "aa": "OPG001: S225L" - } - } - }, - { - "name": "Monkeypox/PT0508/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0508/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555581" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-16" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C4648T", - "C172765T", - "G192562A" - ] - } - } - }, - { - "name": "Monkeypox/PT0538/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0538/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555609" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-23" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G902A", - "C25269T", - "G25692A", - "C196308T", - "-196603A" - ], - "OPG001": [ - "S225L" - ] - }, - "labels": { - "aa": "OPG001: S225L" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI492", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI492" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP626130" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C24929T" - ], - "OPG040": [ - "D184N" - ] - }, - "labels": { - "aa": "OPG040: D184N" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI600", - "node_attrs": { - "div": 5, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI600" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP863250" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G89716A", - "G128858A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G181049-", - "C186220T" - ], - "OPG110": [ - "E29K" - ], - "OPG209": [ - "G178X", - "*191X" - ], - "OPG210": [ - "A1622V" - ] - }, - "labels": { - "aa": "OPG110: E29K; OPG209: G178X, *191X; OPG210: A1622V" - } - } - }, - { - "name": "MPXV/UZ_REGA_17", - "node_attrs": { - "div": 3, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_17" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR030928" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-19" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G902A", - "C68981T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "C196308T" - ], - "OPG001": [ - "S225L" - ], - "OPG087": [ - "S42L" - ] - }, - "labels": { - "aa": "OPG001: S225L; OPG087: S42L" - } - } - }, - { - "name": "MPXV/UZ_REGA_224/Belgium/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logis,A.-S., Bloemen,M., Van Holm,B., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logis,A.-S., Bloemen,M., Van Holm,B., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_224/Belgium/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR095042" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-12" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G34298T", - "C37048T", - "G70190A", - "A146964-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG089": [ - "E109K" - ] - }, - "labels": { - "aa": "OPG089: E109K" - } - } - }, - { - "name": "NODE_0000121", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C80545T" - ], - "OPG103": [ - "S182L" - ] - }, - "labels": { - "aa": "OPG103: S182L" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI540", - "node_attrs": { - "div": 4, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI540" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP715820" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G105792A" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI585", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI585" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP837347" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000122", - "node_attrs": { - "div": 5, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G102614A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "C170573T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG122": [ - "V63I" - ], - "OPG198": [ - "S179L" - ] - }, - "labels": { - "aa": "OPG122: V63I; OPG198: S179L" - } - }, - "children": [ - { - "name": "MPXV/UZ_REGA_108", - "node_attrs": { - "div": 5, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_108" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035714" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-28" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T195509-", - "A195510-", - "A195511-" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_200/Belgium/2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_200/Belgium/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR087009" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-03" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G43620A", - "G123119A" - ], - "OPG143": [ - "S66L" - ] - }, - "labels": { - "aa": "OPG143: S66L" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000123", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G78034A", - "C80111T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG099": [ - "D124N" - ] - }, - "labels": { - "aa": "OPG099: D124N" - } - }, - "children": [ - { - "name": "MPXV/ES0001/HUGTiP/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Martinez-Puchol,S., Coello,A., Bordoy,A.E., Soler,L., Panisello,D., Gonzalez-Gomez,S., Clara,G., Paris de Leon,A., Not,A., Hernandez,A., Bofill-Mas,S., Saludes,V., Blanco,I., Martro,E., Cardona,P.-J.", - "value": "Martinez-Puchol,S., Coello,A., Bordoy,A.E., Soler,L., Panisello,D., Gonzalez-Gomez,S., Clara,G., Paris de Leon,A., Not,A., Hernandez,A., Bofill-Mas,S., Saludes,V., Blanco,I., Martro,E., Cardona,P.-J." - }, - "strain_original": { - "value": "MPXV/ES0001/HUGTiP/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Microbiology, Hospital Universitari Germans Trias i Pujol, Spain" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON622718" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-20" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C14113-", - "-133164C", - "-133165A", - "-133166A", - "-133167T", - "-133168C", - "-133169T", - "-133170T", - "-133171T", - "-133172C", - "-133173T", - "T139150C", - "A178796-", - "T178797-", - "G178798-", - "G178799-", - "G178800-", - "A178801-", - "A178802-", - "T178803-", - "T178804-", - "G178805-", - "G178806-", - "T178807-", - "A178808-", - "A178809-", - "C178810-", - "G178811-", - "A178812-", - "T178813-", - "G178814-", - "A178815-", - "C178816-", - "A178817-", - "G178818-", - "A178819-", - "A178820-", - "A178821-", - "G178822-", - "C178823-", - "A178824-", - "G178825-", - "A178826-", - "T178827-", - "T178828-", - "G178829-", - "T178830-", - "C178831-", - "A178832-", - "G178833-", - "C178834-", - "T178835-", - "C178836-", - "T178837-", - "G178838-", - "C178839-", - "A178840-", - "T178841-", - "A178842-", - "C178843-", - "T178844-", - "A178845-", - "T178846-", - "T178847-", - "C178848-", - "T178849-", - "T178850-", - "C178851-", - "A178852-", - "T178853-", - "G178854-", - "A178855-", - "C178856-", - "A178857-", - "A178858-", - "T178859-", - "A178860-", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-", - "G178879-", - "T178880-", - "T178881-", - "A178882-", - "T178883-", - "G178884-", - "A178885-", - "A178886-", - "G178887-", - "C178888-", - "G178889-", - "T178890-", - "A178891-", - "T178892-", - "-196602A", - "-196603A" - ], - "OPG025": [ - "E385X", - "*631X" - ], - "OPG156": [ - "Q87R" - ] - }, - "labels": { - "aa": "OPG025: E385X, *631X; OPG156: Q87R" - } - } - }, - { - "name": "MpxV/Spain/MD-HGUGM-6532064/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Buenestado-Serrano,S., Palomino-Cabrera,R., Penas-Utrilla,D., Rodriguez-Grande,J., Sola Campoy,P., Perez-Lago,L., Rodriguez-Grande,C., Herranz Martin,M., Suarez,J., Catalan,P., Munoz,P., Garcia de Viedma,D.", - "value": "Buenestado-Serrano,S., Palomino-Cabrera,R., Penas-Utrilla,D., Rodriguez-Grande,J., Sola Campoy,P., Perez-Lago,L., Rodriguez-Grande,C., Herranz Martin,M., Suarez,J., Catalan,P., Munoz,P., Garcia de Viedma,D." - }, - "strain_original": { - "value": "MpxV/Spain/MD-HGUGM-6532064/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Microbial Genomics, Hospital General Universitario Gregorio Marañón, Madrid, Spain" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON720849" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-27" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A322-", - "T596-", - "T597-", - "T598-", - "A1691-", - "A8048-", - "A9523-", - "C11747-", - "T15122-", - "T16095-", - "A19353-", - "A21075-", - "A27108-", - "A28524-", - "A28525-", - "A28596-", - "T32188-", - "A33193-", - "T34040-", - "T35565-", - "T37976-", - "T39127-", - "T39861-", - "T41738-", - "A43502-", - "T43503-", - "C43504T", - "T43505C", - "T46643-", - "A55119-", - "T56035-", - "A57274-", - "A58644-", - "A62034-", - "T64749-", - "A64931-", - "G69145-", - "A69739-", - "T76079-", - "T76080-", - "A76883-", - "A79177-", - "T79226-", - "A79457-", - "A79782-", - "T80841-", - "T88090-", - "T88831-", - "A89100-", - "A91698-", - "T94640-", - "T94789-", - "A98077-", - "T103362-", - "T105355-", - "T108710-", - "A110973-", - "T114514-", - "T114751-", - "A116008-", - "T116958-", - "T121116-", - "C122649T", - "A123988-", - "A124720-", - "A127246-", - "A127747-", - "A128927-", - "A132020-", - "A132021-", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "T133633-", - "T137881-", - "A138468-", - "A142462-", - "A144224-", - "A147994-", - "T148337-", - "T150532-", - "G150577-", - "A150578-", - "T150579-", - "A150580-", - "T150581-", - "G150582-", - "A150583-", - "T150584-", - "G150620-", - "G150621-", - "A150622-", - "T150623-", - "A150624-", - "T150625-", - "G150626-", - "A150627-", - "T150628-", - "A150629-", - "A151980-", - "A152668-", - "T152680-", - "A153418-", - "A154123-", - "T155417-", - "A157991-", - "T163592-", - "T168116-", - "A168956-", - "A170723-", - "T170897-", - "T172079-", - "T172661-", - "T178041-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "A179945-", - "G181049-", - "A181246-", - "A182643-", - "T187073-", - "A190929-", - "T195513-", - "A196588-", - "A196604-", - "A196605-", - "A196606-", - "A196607-", - "T197177-" - ], - "NBT03_gp052": [ - "L8X", - "*130X" - ], - "NBT03_gp174": [ - "K174X", - "*177X" - ], - "OPG023": [ - "G385X", - "*661X" - ], - "OPG025": [ - "N49X", - "*631X" - ], - "OPG027": [ - "T95X", - "*151X" - ], - "OPG044": [ - "E145X", - "*150X" - ], - "OPG050": [ - "F72X", - "*76X" - ], - "OPG054": [ - "K144X", - "*440X" - ], - "OPG056": [ - "K353X", - "*636X" - ], - "OPG057": [ - "N112X", - "I357X", - "*373X" - ], - "OPG061": [ - "K49X", - "*232X" - ], - "OPG063": [ - "R62X", - "F63X", - "*480X" - ], - "OPG074": [ - "N364X", - "*666X" - ], - "OPG075": [ - "F75X", - "*109X" - ], - "OPG078": [ - "F56X", - "*74X" - ], - "OPG084": [ - "F10X", - "G70X", - "*677X" - ], - "OPG087": [ - "G97X", - "*221X" - ], - "OPG088": [ - "L42X", - "*125X" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG102": [ - "A31X", - "F48X", - "K125X", - "E233X", - "*334X" - ], - "OPG104": [ - "N60X", - "*134X" - ], - "OPG109": [ - "F116X", - "K206X", - "K453X", - "*796X" - ], - "OPG114": [ - "I10X", - "*147X" - ], - "OPG115": [ - "F44X", - "*234X" - ], - "OPG117": [ - "K677X", - "*786X" - ], - "OPG123": [ - "N570X", - "*632X" - ], - "OPG124": [ - "N205X", - "*288X" - ], - "OPG127": [ - "K39X", - "*225X" - ], - "OPG129": [ - "L11X", - "*645X" - ], - "OPG133": [ - "I316X", - "I395X", - "*711X" - ], - "OPG134": [ - "K87X", - "*293X" - ], - "OPG136": [ - "N877X", - "*892X" - ], - "OPG138": [ - "N6X", - "*191X" - ], - "OPG143": [ - "D223N" - ], - "OPG145": [ - "L14X", - "L258X", - "*493X" - ], - "OPG148": [ - "K421X", - "*427X" - ], - "OPG149": [ - "S17X", - "I184X", - "*188X" - ], - "OPG150": [ - "*383X" - ], - "OPG151": [ - "K2X", - "K1033X", - "*1165X" - ], - "OPG154": [ - "K57X", - "*111X" - ], - "OPG155": [ - "F8X", - "*147X" - ], - "OPG163": [ - "S87X", - "*177X" - ], - "OPG165": [ - "K237X", - "*269X" - ], - "OPG172": [ - "K190X", - "*197X" - ], - "OPG178": [ - "K158X", - "*205X" - ], - "OPG180": [ - "K243X", - "K478X", - "*560X" - ], - "OPG189": [ - "I87X", - "*562X" - ], - "OPG193": [ - "T261X", - "*268X" - ], - "OPG198": [ - "Q229X", - "*283X" - ], - "OPG208": [ - "E227X", - "*358X" - ], - "OPG209": [ - "G178X", - "*191X" - ], - "OPG210": [ - "K430X", - "*1881X" - ] - }, - "labels": { - "aa": "NBT03_gp052: L8X, *130X; NBT03_gp174: K174X, *177X; OPG023: G385X, *661X; OPG025: N49X, *631X; OPG027: T95X, *151X; OPG044: E145X, *150X; OPG050: F72X, *76X; OPG054: K144X, *440X; OPG056: K353X, *636X; OPG057: N112X, I357X, *373X; OPG061: K49X, *232X; OPG063: R62X, F63X, *480X; OPG074: N364X, *666X; OPG075: F75X, *109X; OPG078: F56X, *74X; OPG084: F10X, G70X, *677X; OPG087: G97X, *221X; OPG088: L42X, *125X; OPG097: K266X, *345X; OPG102: A31X, F48X, K125X, E233X, *334X; OPG104: N60X, *134X; OPG109: F116X, K206X, K453X, *796X; OPG114: I10X, *147X; OPG115: F44X, *234X; OPG117: K677X, *786X; OPG123: N570X, *632X; OPG124: N205X, *288X; OPG127: K39X, *225X; OPG129: L11X, *645X; OPG133: I316X, I395X, *711X; OPG134: K87X, *293X; OPG136: N877X, *892X; OPG138: N6X, *191X; OPG143: D223N; OPG145: L14X, L258X, *493X; OPG148: K421X, *427X; OPG149: S17X, I184X, *188X; OPG150: *383X; OPG151: K2X, K1033X, *1165X; OPG154: K57X, *111X; OPG155: F8X, *147X; OPG163: S87X, *177X; OPG165: K237X, *269X; OPG172: K190X, *197X; OPG178: K158X, *205X; OPG180: K243X, K478X, *560X; OPG189: I87X, *562X; OPG193: T261X, *268X; OPG198: Q229X, *283X; OPG208: E227X, *358X; OPG209: G178X, *191X; OPG210: K430X, *1881X" - } - } - }, - { - "name": "NODE_0000124", - "node_attrs": { - "div": 5, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G22643A", - "G63811A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-" - ], - "OPG038": [ - "H173Y" - ] - }, - "labels": { - "aa": "OPG038: H173Y" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_FL0018", - "node_attrs": { - "div": 5, - "author": { - "author": "Gigante,C.M., Lee,P., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Mendoza,R., Li,Y.", - "value": "Gigante,C.M., Lee,P., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Mendoza,R., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_FL0018" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP303781" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-23631-L", - "node_attrs": { - "div": 5, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-23631-L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP459214" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-30" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-23265-C", - "node_attrs": { - "div": 5, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-23265-C" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP477452" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-23" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI497", - "node_attrs": { - "div": 7, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI497" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP626136" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C64635T", - "G141114A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ], - "OPG083": [ - "A28T" - ], - "OPG161": [ - "E5K" - ] - }, - "labels": { - "aa": "OPG083: A28T; OPG161: E5K" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-24722-L", - "node_attrs": { - "div": 6, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-24722-L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP642374" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-08" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G168759A", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ], - "OPG195": [ - "R177K" - ] - }, - "labels": { - "aa": "OPG195: R177K" - } - } - }, - { - "name": "MPXV_USA_2022_FL0023", - "node_attrs": { - "div": 6, - "author": { - "author": "Gigante,C.M., Lee,P., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Morrison,S.S., Seabolt,M.H., Weigand,M.R., Knipe,K., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Stanek,D., Li,Y.", - "value": "Gigante,C.M., Lee,P., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Morrison,S.S., Seabolt,M.H., Weigand,M.R., Knipe,K., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Stanek,D., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_FL0023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP687931" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C36709T", - "A179074-", - "T179075-", - "G179076-", - "-179101A", - "-179102T", - "-179103T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T" - ] - } - } - }, - { - "name": "MPXV_USA_2022_FL0009", - "node_attrs": { - "div": 9, - "author": { - "author": "Gigante,C., Lee,P., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Stanek,D., Li,Y.", - "value": "Gigante,C., Lee,P., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Stanek,D., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_FL0009" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ320513" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-XX" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G4038A", - "A39081T", - "C67289T", - "G73790A", - "T133078-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "C193172T" - ], - "OPG057": [ - "I372N" - ], - "OPG085": [ - "E415K" - ], - "OPG094": [ - "G4E" - ] - }, - "labels": { - "aa": "OPG057: I372N; OPG085: E415K; OPG094: G4E" - } - } - }, - { - "name": "NY-NYCPHL-000918", - "node_attrs": { - "div": 6, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000918" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468531" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-08" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G8223A", - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T" - ] - } - } - }, - { - "name": "NY-NYCPHL-001054", - "node_attrs": { - "div": 5, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-001054" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469243" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-27" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T" - ] - } - } - }, - { - "name": "MPXV_USA_2022_WI0002", - "node_attrs": { - "div": 8, - "author": { - "author": "Gigante,C., Segaloff,H., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Florek,K., Li,Y.", - "value": "Gigante,C., Segaloff,H., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Florek,K., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_WI0002" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ721943" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G22108A", - "G93387A", - "C144233T" - ], - "OPG037": [ - "S109L" - ], - "OPG113": [ - "E553K" - ], - "OPG165": [ - "Q240*" - ] - }, - "labels": { - "aa": "OPG037: S109L; OPG113: E553K; OPG165: Q240*" - } - } - }, - { - "name": "NODE_0000125", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T119985C", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T" - ] - } - }, - "children": [ - { - "name": "MPX_imBNaw_9000300", - "node_attrs": { - "div": 7, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_imBNaw_9000300" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415254" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G189258A" - ] - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-092889/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-092889/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP681774" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000126", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C127215T" - ], - "OPG149": [ - "S7L" - ] - }, - "labels": { - "aa": "OPG149: S7L" - } - }, - "children": [ - { - "name": "NY-NYCPHL-000302", - "node_attrs": { - "div": 8, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000302" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468475" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-04" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "T133079-", - "G169558A", - "C172154T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T" - ], - "OPG200": [ - "T2M" - ] - }, - "labels": { - "aa": "OPG200: T2M" - } - } - }, - { - "name": "MPXV_USA_2022_TX0047", - "node_attrs": { - "div": 7, - "author": { - "author": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y.", - "value": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_TX0047" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ557957" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C84485T", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-" - ] - } - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000127", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C70780T" - ] - }, - "labels": { - "clade": "B.1.5" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI048", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI048" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON755254" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G28706A", - "C51885T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG045": [ - "P186L" - ], - "OPG071": [ - "E852K" - ] - }, - "labels": { - "aa": "OPG045: P186L; OPG071: E852K" - } - } - }, - { - "name": "INMI-Pt4", - "node_attrs": { - "div": 1, - "author": { - "author": "Gramigna,G., Giombini,E., Gruber,C.E.M., Rueca,M., Carletti,F., Cicalini,S., Lapa,D., Puro,V., Marani,A., Fabeni,L., Butera,O., Colavita,F., Meschi,S., Matusali,G., Rivano Capparuccia,M., Specchiarello,E., Vairo,F., Vaia,F., Nicastri,E., Antinori,A., Girardi,E., Maggi,F.", - "value": "Gramigna,G., Giombini,E., Gruber,C.E.M., Rueca,M., Carletti,F., Cicalini,S., Lapa,D., Puro,V., Marani,A., Fabeni,L., Butera,O., Colavita,F., Meschi,S., Matusali,G., Rivano Capparuccia,M., Specchiarello,E., Vairo,F., Vaia,F., Nicastri,E., Antinori,A., Girardi,E., Maggi,F." - }, - "strain_original": { - "value": "INMI-Pt4" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON780017" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Italy" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-21" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - }, - { - "name": "hMpxV/Switzerland/ZH-UZH-IMV-3ba64538/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Kufner,V., Ziltener,G., Zaheri,M., Schmutz,S., Audige,A., Bernasconi,O., Steiner,K., Huder,J., Shah,C., Capaul,R., Bloemberg,G., Boeni,J., Huber,M., Trkola,A.", - "value": "Kufner,V., Ziltener,G., Zaheri,M., Schmutz,S., Audige,A., Bernasconi,O., Steiner,K., Huder,J., Shah,C., Capaul,R., Bloemberg,G., Boeni,J., Huber,M., Trkola,A." - }, - "strain_original": { - "value": "hMpxV/Switzerland/ZH-UZH-IMV-3ba64538/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Zurich, Institute of Medical Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON792322" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Switzerland" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-02" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/human/Taiwan/110-231642/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "strain_original": { - "value": "MPXV/human/Taiwan/110-231642/2022" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON918656" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Taiwan" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C28702T", - "T34793C", - "T50861C", - "C51777T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG054": [ - "T402A" - ], - "OPG070": [ - "V91A" - ], - "OPG071": [ - "E888K" - ] - }, - "labels": { - "aa": "OPG054: T402A; OPG070: V91A; OPG071: E888K" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI162", - "node_attrs": { - "div": 1, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI162" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON959175" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV_USA_2022_GA001", - "node_attrs": { - "div": 1, - "author": { - "author": "Gigante,C., Xia,D., Seabolt,M., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Plipat,N., Li,Y.", - "value": "Gigante,C., Xia,D., Seabolt,M., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Plipat,N., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_GA001" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP150925" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI327", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI327" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP355582" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6619A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A188349-" - ] - } - } - }, - { - "name": "Monkeypox/PT0244/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0244/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP414288" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-21" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-196603A" - ] - } - } - }, - { - "name": "Monkeypox/PT0390/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0390/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555486" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-11" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI522", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI522" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP689675" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G117447A", - "A133328T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG136": [ - "S714L" - ] - }, - "labels": { - "aa": "OPG136: S714L" - } - } - }, - { - "name": "hMPXV-CH-38347314/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Laubscher,F., Marques-Melancia,S., Cordey,S., Schibler,M., Kaiser,L., Renzoni,A.", - "value": "Laubscher,F., Marques-Melancia,S., Cordey,S., Schibler,M., Kaiser,L., Renzoni,A." - }, - "strain_original": { - "value": "hMPXV-CH-38347314/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University Hospitals of Geneva, Laboratory of Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP783902" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Switzerland" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-08" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI662", - "node_attrs": { - "div": 1, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI662" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ274881" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A152668-", - "T152680-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI667", - "node_attrs": { - "div": 1, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI667" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ274886" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A152668-", - "T152680-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI824", - "node_attrs": { - "div": 5, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI824" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773443" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C69494T", - "C89921T", - "G135954A", - "G144572A", - "G150550-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG087": [ - "S213L" - ], - "OPG088": [ - "E124K" - ], - "OPG110": [ - "S97L" - ] - }, - "labels": { - "aa": "OPG087: S213L; OPG088: E124K; OPG110: S97L" - } - } - }, - { - "name": "Monkeypox/PT0033/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0033/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON843165" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-24" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI406", - "node_attrs": { - "div": 1, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI406" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP524008" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "NODE_0000129", - "node_attrs": { - "div": 5, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G71227A", - "C133867T", - "C134247T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G158866A" - ], - "OPG090": [ - "E17K" - ] - }, - "labels": { - "aa": "OPG090: E17K" - } - }, - "children": [ - { - "name": "MPX/PT0064/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "MPX/PT0064/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP245318" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-01" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0515/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0515/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555586" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-16" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G58545A" - ] - } - } - } - ] - }, - { - "name": "NODE_0000130", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A550-", - "T551-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G159001A", - "C196435-", - "G196436-" - ], - "OPG185": [ - "D29N" - ] - }, - "labels": { - "aa": "OPG185: D29N" - } - }, - "children": [ - { - "name": "MPX/PT0090/2022", - "node_attrs": { - "div": 2, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "MPX/PT0090/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP245340" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-21" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0579/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0579/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555650" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-10" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C41022T", - "A136513-", - "T136514-", - "C136515-" - ], - "OPG060": [ - "R54K" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG060: R54K; OPG153: D385-" - } - } - } - ] - }, - { - "name": "NODE_0000131", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C150392T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG176": [ - "S195F" - ] - }, - "labels": { - "aa": "OPG176: S195F" - } - }, - "children": [ - { - "name": "9000376", - "node_attrs": { - "div": 3, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "9000376" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536756" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C69888T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG089": [ - "S8L" - ] - }, - "labels": { - "aa": "OPG089: S8L" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI441", - "node_attrs": { - "div": 5, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI441" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP594205" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C22982T", - "C49265T", - "C124495T" - ], - "OPG038": [ - "E60K" - ] - }, - "labels": { - "aa": "OPG038: E60K" - } - } - } - ] - }, - { - "name": "NODE_0000132", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C44333T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG064": [ - "M522I" - ] - }, - "labels": { - "aa": "OPG064: M522I" - } - }, - "children": [ - { - "name": "MPX_luLfgA_9000208", - "node_attrs": { - "div": 2, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_luLfgA_9000208" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415189" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/UZ_REGA_69", - "node_attrs": { - "div": 3, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_69" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035675" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-30" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G161488A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_96", - "node_attrs": { - "div": 6, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_96" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035702" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-30" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C29315T", - "C60396T", - "G149807A", - "C161572T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG046": [ - "D139N" - ] - }, - "labels": { - "aa": "OPG046: D139N" - } - } - }, - { - "name": "NODE_0000133", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G93512T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG113": [ - "K594N" - ] - }, - "labels": { - "aa": "OPG113: K594N" - } - }, - "children": [ - { - "name": "SIC-AOUP-UNIPA_VL_9aug", - "node_attrs": { - "div": 6, - "author": { - "author": "Tramuto,F.", - "value": "Tramuto,F." - }, - "strain_original": { - "value": "SIC-AOUP-UNIPA_VL_9aug" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Palermo, Department of Health Promotion Sciences Maternal and Infant Care, Internal Medicine and Medical Specialties \"G. D'Alessandro\"" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP358276" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Italy" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-09" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C33103T", - "C114490T", - "C133295T", - "T179026-", - "A179027-", - "T179028-", - "G179029-", - "A179030-", - "A179031-", - "T179032-", - "A179033-", - "C179034-", - "G179035-", - "G179036-", - "A179037-", - "G179038-", - "T179039-", - "A179040-", - "C179041-", - "A179042-", - "A179043-" - ], - "OPG049": [ - "E17K" - ], - "OPG133": [ - "D403N" - ] - }, - "labels": { - "aa": "OPG049: E17K; OPG133: D403N" - } - } - }, - { - "name": "9000394", - "node_attrs": { - "div": 5, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "9000394" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536772" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C756T", - "G2898A", - "G3477A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C193733T", - "C194312T", - "G196454A" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000134", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C160426T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - }, - "children": [ - { - "name": "NODE_0000135", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A10432-", - "T10433-", - "T10434-", - "A10435-", - "G10436-", - "G75332A", - "T124690C", - "C144211T", - "G185394A" - ], - "OPG095": [ - "R177K" - ], - "OPG210": [ - "E1347K" - ] - }, - "labels": { - "aa": "OPG095: R177K; OPG210: E1347K" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-113327/2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-113327/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503755" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-XX" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C135762T" - ] - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-119069/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-119069/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503754" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-XX" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000136", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G111379A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G165326A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG130": [ - "S175L" - ], - "OPG190": [ - "E69K" - ] - }, - "labels": { - "aa": "OPG130: S175L; OPG190: E69K" - } - }, - "children": [ - { - "name": "NJ-MPXV-006-rpt1", - "node_attrs": { - "div": 4, - "author": { - "author": "Palmateer,N.C.", - "value": "Palmateer,N.C." - }, - "strain_original": { - "value": "NJ-MPXV-006-rpt1" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "New Jersey Department of Health, Public Health and Environmental Laboratories" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP879727" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - }, - { - "name": "NY-NYCPHL-000617", - "node_attrs": { - "div": 4, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000617" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468715" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-10" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-" - ] - } - } - }, - { - "name": "NY-NYCPHL-000775", - "node_attrs": { - "div": 4, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000775" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468793" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-12" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NY-NYCPHL-000455", - "node_attrs": { - "div": 7, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000455" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468992" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-21" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C14655T", - "G22207A", - "C120671T", - "A150566-" - ], - "OPG025": [ - "E205K" - ], - "OPG037": [ - "S76F" - ] - }, - "labels": { - "aa": "OPG025: E205K; OPG037: S76F" - } - } - }, - { - "name": "NY-NYCPHL-000191", - "node_attrs": { - "div": 5, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000191" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469045" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-30" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G175617A" - ] - } - } - }, - { - "name": "NY-NYCPHL-000132", - "node_attrs": { - "div": 4, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000132" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469143" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-26" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-" - ] - } - } - }, - { - "name": "NODE_0000137", - "node_attrs": { - "div": 9, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G74391A", - "G98473A", - "C124495T", - "C132962T", - "C149264T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-196603A" - ], - "OPG094": [ - "M204I" - ], - "OPG118": [ - "D10N" - ] - }, - "labels": { - "aa": "OPG094: M204I; OPG118: D10N" - } - }, - "children": [ - { - "name": "NY-NYCPHL-000425", - "node_attrs": { - "div": 9, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000425" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ504436" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-12" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV_USA_2022_NY0046", - "node_attrs": { - "div": 9, - "author": { - "author": "Gigante,C., Ruiz,V., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Wang,J., Li,Y.", - "value": "Gigante,C., Ruiz,V., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Wang,J., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_NY0046" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ721932" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-" - ] - } - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000138", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G74360A" - ], - "OPG094": [ - "R194H" - ] - }, - "labels": { - "aa": "OPG094: R194H", - "clade": "B.1.1" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI025", - "node_attrs": { - "div": 1, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI025" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON694329" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A192404-", - "G192405-", - "T192406-", - "C192407-", - "A192408-", - "T192409-", - "A192410-", - "A192411-", - "G192412-", - "T192413-", - "T192414-", - "A192415-", - "G192416-", - "T192417-", - "T192418-", - "A192419-", - "A192420-", - "G192421-", - "T192422-", - "C192423-", - "A192424-", - "T192425-", - "A192426-", - "A192427-", - "G192428-", - "T192429-", - "T192430-", - "A192431-", - "G192432-", - "T192433-", - "T192434-", - "A192435-", - "A192436-", - "G192437-", - "T192438-", - "C192439-", - "A192440-", - "T192441-", - "A192442-", - "A192443-", - "G192444-", - "T192445-", - "T192446-", - "A192447-", - "G192448-", - "T192449-", - "T192450-", - "A192451-" - ] - } - } - }, - { - "name": "hMpxV/Switzerland/ZH-UZH-IMV-3ba6450e/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Kufner,V., Ziltener,G., Zaheri,M., Schmutz,S., Audige,A., Bernasconi,O., Steiner,K., Huder,J., Shah,C., Capaul,R., Bloemberg,G., Boeni,J., Huber,M., Trkola,A.", - "value": "Kufner,V., Ziltener,G., Zaheri,M., Schmutz,S., Audige,A., Bernasconi,O., Steiner,K., Huder,J., Shah,C., Capaul,R., Bloemberg,G., Boeni,J., Huber,M., Trkola,A." - }, - "strain_original": { - "value": "hMpxV/Switzerland/ZH-UZH-IMV-3ba6450e/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Zurich, Institute of Medical Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON792321" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Switzerland" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-02" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T9151-", - "A9152-", - "T9153-", - "T9154-", - "T9155-", - "T9156-", - "A9157-", - "T9158-", - "A9159-", - "A9160-", - "T9161-", - "A9162-", - "A9163-", - "T9164-", - "G9165-", - "T19299-", - "A19300-", - "C19301-", - "T19302-", - "A19303-", - "A19304-", - "G43539-", - "T43540-", - "C43541-", - "T49124-", - "G49125-", - "A49126-", - "T49127-", - "G49128-", - "C49129-", - "A49130-", - "A49131-", - "A49132-", - "A49133-", - "A49134-", - "A49135-", - "C49136-", - "G49137-", - "A49138-", - "C49139-", - "G49140-", - "A49141-", - "T79020-", - "A79021-", - "T79022-", - "T79023-", - "A79024-", - "T79025-", - "A79026-", - "T79027-", - "T79028-", - "T79029-", - "T79030-", - "T79031-", - "T79032-", - "A79033-", - "T79034-", - "C79035-", - "T79036-", - "A79037-", - "A79038-", - "A79039-", - "A79040-", - "A79041-", - "A79042-", - "C79043-", - "T79044-", - "A79045-", - "A79046-", - "A79047-", - "A79048-", - "A79049-", - "T79050-", - "A79051-", - "A79052-", - "A79053-", - "C79054-", - "A79055-", - "T79056-", - "T79057-", - "G79058-", - "A79059-", - "T152633-", - "C152634-", - "T152635-", - "A152636-", - "A152637-", - "T152638-", - "G152639-", - "A152640-", - "C175864-", - "A175865-", - "T175866-", - "C175867-", - "T175868-", - "A175869-", - "G175870-", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127A", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136T", - "-179137A", - "-179138A", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179148T", - "T179156-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "C179190T", - "A180392-", - "G180393-", - "T180394-", - "A180395-", - "T180396-", - "A180397-", - "G180398-" - ], - "OPG063": [ - "D50-" - ], - "OPG068": [ - "I308X", - "D309-", - "A310-", - "K311-", - "N312-", - "D313-", - "D314X", - "*568X" - ], - "OPG205": [ - "S70X", - "S71-", - "S72X", - "*788X" - ] - }, - "labels": { - "aa": "OPG063: D50-; OPG068: I308X, D309-, A310-, K311-, N312-, D313-, D314X, *568X; OPG205: S70X, S71-, S72X, *788X" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI059", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Stocker,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Stocker,H., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI059" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON813256" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G142240A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI094", - "node_attrs": { - "div": 1, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI094" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON853673" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV-ROK-P1-2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Rhie,G.-E.", - "value": "Rhie,G.-E." - }, - "strain_original": { - "value": "MPXV-ROK-P1-2022" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Korea Disease Control and Prevention Agency, Division of High-risk Pathogens" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP204857" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "South Korea" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C786T", - "C71728T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G173429A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG091": [ - "A120V" - ] - }, - "labels": { - "aa": "OPG091: A120V" - } - } - }, - { - "name": "hMPXV-IHU00002", - "node_attrs": { - "div": 1, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "strain_original": { - "value": "hMPXV-IHU00002" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP382479" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-01" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "hMPXV-IHU00011", - "node_attrs": { - "div": 2, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "strain_original": { - "value": "hMPXV-IHU00011" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP382488" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-19" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "-595T", - "C153387T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A196599-", - "C196600-", - "-196602A" - ] - } - } - }, - { - "name": "9000426", - "node_attrs": { - "div": 1, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "9000426" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536800" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "T190786-", - "T190787-", - "A196604-" - ], - "NBT03_gp174": [ - "I126X", - "*177X" - ] - }, - "labels": { - "aa": "NBT03_gp174: I126X, *177X" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI555", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI555" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP715835" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C71059T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI674", - "node_attrs": { - "div": 1, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI674" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ319132" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A152668-", - "T152680-" - ] - } - } - }, - { - "name": "MPXV_USA_2022_IN0006", - "node_attrs": { - "div": 4, - "author": { - "author": "Gigante,C., Culbertson,M., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Weigand,M., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Pope,B., Li,Y.", - "value": "Gigante,C., Culbertson,M., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Weigand,M., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Pope,B., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_IN0006" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ320518" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T22135C", - "G52232A", - "C119838T", - "A136513-", - "T136514-", - "C136515-" - ], - "OPG037": [ - "H100R" - ], - "OPG071": [ - "S736L" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG037: H100R; OPG071: S736L; OPG153: D385-" - } - } - }, - { - "name": "MPXV/UZ_REGA_218/Belgium/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_218/Belgium/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR095036" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-08" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C25828T", - "G107496A", - "G109463A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG042": [ - "E424K" - ] - }, - "labels": { - "aa": "OPG042: E424K" - } - } - }, - { - "name": "NODE_0000139", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C134504T" - ] - } - }, - "children": [ - { - "name": "MPXV_USA_2022_NY0014", - "node_attrs": { - "div": 2, - "author": { - "author": "Gigante,C.M., Hughes,S., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Baumgartner,J., Li,Y.", - "value": "Gigante,C.M., Hughes,S., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Baumgartner,J., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_NY0014" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP303789" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NY-NYCPHL-000070", - "node_attrs": { - "div": 2, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000070" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468926" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-14" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - } - ] - }, - { - "name": "NODE_0000140", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "A136513-", - "T136514-", - "C136515-", - "G160406A", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_NV0003", - "node_attrs": { - "div": 3, - "author": { - "author": "Gigante,C.M., Buttery,E., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Knipe,K., Burroughs,S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Raman,D., Li,Y.", - "value": "Gigante,C.M., Buttery,E., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Knipe,K., Burroughs,S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Raman,D., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_NV0003" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP604524" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C68484T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T" - ], - "OPG085": [ - "M16I" - ] - }, - "labels": { - "aa": "OPG085: M16I" - } - } - }, - { - "name": "MPXV_USA_2022_NE0006", - "node_attrs": { - "div": 4, - "author": { - "author": "Li,C.M.", - "value": "Li,C.M." - }, - "strain_original": { - "value": "MPXV_USA_2022_NE0006" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR209326" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G11924A", - "G34800A" - ], - "OPG023": [ - "S326L" - ] - }, - "labels": { - "aa": "OPG023: S326L" - } - } - } - ] - }, - { - "name": "NODE_0000141", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C17048T", - "G93828A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G177009A" - ], - "OPG029": [ - "D8N" - ], - "OPG113": [ - "E700K" - ], - "OPG205": [ - "E452K" - ] - }, - "labels": { - "aa": "OPG029: D8N; OPG113: E700K; OPG205: E452K" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI633", - "node_attrs": { - "div": 5, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI633" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ159028" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C41131T" - ], - "OPG060": [ - "E18K" - ] - }, - "labels": { - "aa": "OPG060: E18K" - } - } - }, - { - "name": "MPXV/PT0626/2023", - "node_attrs": { - "div": 11, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "MPXV/PT0626/2023" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ735077" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-03-21" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A571-", - "G572-", - "C10929T", - "C22179T", - "G39515A", - "G77076A", - "G129659A", - "C129949T", - "G139167A", - "G196594-", - "T196595-", - "-196601A" - ], - "OPG023": [ - "E658K" - ], - "OPG151": [ - "E246K" - ] - }, - "labels": { - "aa": "OPG023: E658K; OPG151: E246K" - } - } - } - ] - }, - { - "name": "NODE_0000142", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C11401T", - "A136513-", - "T136514-", - "C136515-", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_NV0005", - "node_attrs": { - "div": 4, - "author": { - "author": "Gigante,C., Buttery,E., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Knipe,K., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Raman,D., Li,Y.", - "value": "Gigante,C., Buttery,E., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Knipe,K., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Raman,D., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_NV0005" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ427112" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C72269T", - "T133078-", - "G140194A", - "G158318A" - ], - "OPG092": [ - "D227N" - ], - "OPG159": [ - "D143N" - ], - "OPG160": [ - "S294L" - ] - }, - "labels": { - "aa": "OPG092: D227N; OPG159: D143N; OPG160: S294L" - } - } - }, - { - "name": "MPXV_USA_2022_TX0051", - "node_attrs": { - "div": 4, - "author": { - "author": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y.", - "value": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_TX0051" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ721942" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G23673A", - "G50121A", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T" - ], - "OPG039": [ - "S149L" - ], - "OPG069": [ - "E46K" - ] - }, - "labels": { - "aa": "OPG039: S149L; OPG069: E46K" - } - } - } - ] - }, - { - "name": "NODE_0000143", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G155698A" - ] - } - }, - "children": [ - { - "name": "MPXV/UZ_REGA_180/Belgium/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_180/Belgium/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR086989" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-27" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C7037T", - "G10930A", - "C109896T", - "T133078-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG129": [ - "R370K" - ] - }, - "labels": { - "aa": "OPG129: R370K" - } - } - }, - { - "name": "NODE_0000144", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G138237A" - ] - } - }, - "children": [ - { - "name": "MpxV/human/USA/OH-UW-078654/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A." - }, - "strain_original": { - "value": "MpxV/human/USA/OH-UW-078654/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP123052" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C11562T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG023": [ - "D447N" - ] - }, - "labels": { - "aa": "OPG023: D447N" - } - } - }, - { - "name": "Monkeypox/PT0592/2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0592/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555659" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-14" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C21910T", - "C67207T", - "G81244A", - "G109451A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A196524-", - "C196525-" - ], - "OPG037": [ - "R175K" - ], - "OPG085": [ - "R442K" - ], - "OPG105": [ - "R40K" - ] - }, - "labels": { - "aa": "OPG037: R175K; OPG085: R442K; OPG105: R40K" - } - } - } - ] - }, - { - "name": "NODE_0000145", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G161575A", - "-196603A" - ] - } - }, - "children": [ - { - "name": "Monkeypox/PT0377/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0377/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555473" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-06" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0474/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0474/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555553" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-08" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C54306T", - "G121773A" - ], - "OPG071": [ - "E45K" - ], - "OPG141": [ - "S51L" - ] - }, - "labels": { - "aa": "OPG071: E45K; OPG141: S51L" - } - } - }, - { - "name": "MPXV/UZ_REGA_133/Belgium/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_133/Belgium/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR086942" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-05" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "T149487-", - "A149488-", - "C149489-", - "G149490-", - "T149491-", - "T149492-", - "G149493-", - "A149494-", - "A149495-", - "C149496-", - "A149497-", - "A149498-", - "G149499-", - "T149500-", - "C149501-", - "C149502-", - "A149503-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG175": [ - "Y16-", - "V17-", - "E18-", - "Q19-", - "V20-", - "H21X", - "*126X" - ] - }, - "labels": { - "aa": "OPG175: Y16-, V17-, E18-, Q19-, V20-, H21X, *126X" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000146", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C22739T" - ], - "OPG038": [ - "E141K" - ] - }, - "labels": { - "aa": "OPG038: E141K" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI01", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI01" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON637938" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C169722-", - "A169723-", - "G169724-", - "A169725-", - "T169726-", - "A169727-", - "C169728-", - "A169729-", - "G169730-", - "A169731-", - "T169732-", - "A169733-", - "C169734-", - "A169735-", - "G169736-", - "A169737-", - "T169738-", - "A169739-", - "C169740-", - "A169741-", - "G169742-", - "A169743-", - "T169744-", - "A169745-", - "C169746-", - "A169747-", - "G169748-", - "A169749-", - "T169750-", - "A169751-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-" - ], - "OPG197": [ - "S18X", - "D19-", - "T20-", - "D21-", - "T22-", - "D23-", - "T24-", - "D25-", - "T26-", - "D27-", - "T28X", - "*101X" - ] - }, - "labels": { - "aa": "OPG197: S18X, D19-, T20-, D21-, T22-, D23-, T24-, D25-, T26-, D27-, T28X, *101X" - } - } - }, - { - "name": "CVR_MPXV1a", - "node_attrs": { - "div": 2, - "author": { - "author": "Filipe,A., Tong,L., Vattipally,S.B., Maclean,A., Gunson,R., Holden,M.T.G., Barr,D., Ho,A., Palmarini,M., Rambaut,A., Robertson,D.L., Thomson,E.C.", - "value": "Filipe,A., Tong,L., Vattipally,S.B., Maclean,A., Gunson,R., Holden,M.T.G., Barr,D., Ho,A., Palmarini,M., Rambaut,A., Robertson,D.L., Thomson,E.C." - }, - "strain_original": { - "value": "CVR_MPXV1a" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON808413" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-15" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133098-", - "T133099-", - "T133100-", - "T133101-", - "T133102-", - "C133103-", - "A136513-", - "T136514-", - "C136515-", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "hMPXV/Austria/MUW1527495/2022", - "node_attrs": { - "div": 2, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1527495/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP019276" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Austria" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-21" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV_UK_2022_9000179", - "node_attrs": { - "div": 2, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPXV_UK_2022_9000179" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205128" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-26" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPX_dDDHx_9000207", - "node_attrs": { - "div": 3, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_dDDHx_9000207" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415188" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A33221-", - "T33222-", - "A33223-", - "T33224-", - "T33225-", - "C33226-", - "T33227-", - "C33228-", - "A33229-", - "T33230-", - "T33231-", - "G33232-", - "C33233-", - "T33234-", - "C144199T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG050": [ - "S59-", - "N60-", - "E61-", - "N62-", - "I63X", - "*76X" - ] - }, - "labels": { - "aa": "OPG050: S59-, N60-, E61-, N62-, I63X, *76X" - } - } - }, - { - "name": "MPX_XAF7gk_9000317", - "node_attrs": { - "div": 3, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_XAF7gk_9000317" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415258" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C172730T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI397", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI397" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP523996" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "NODE_0000147", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C186124T", - "C189996T" - ], - "OPG210": [ - "S1590F" - ] - }, - "labels": { - "aa": "OPG210: S1590F" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI247", - "node_attrs": { - "div": 4, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI247" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP215267" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV_USA_2022_AK0001", - "node_attrs": { - "div": 7, - "author": { - "author": "Gigante,C., Mooring,E., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Laurence,J., Li,Y.", - "value": "Gigante,C., Mooring,E., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Laurence,J., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_AK0001" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ054241" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C19558T", - "C101074T", - "C151047T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG034": [ - "E150K" - ] - }, - "labels": { - "aa": "OPG034: E150K" - } - } - } - ] - }, - { - "name": "NODE_0000148", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C144256T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G170785A" - ], - "OPG198": [ - "E250K" - ] - }, - "labels": { - "aa": "OPG198: E250K" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI259", - "node_attrs": { - "div": 5, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI259" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP215278" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G15876A" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI388", - "node_attrs": { - "div": 7, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI388" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP523990" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6376A", - "G13107A", - "G117345A", - "C190834T" - ], - "NBT03_gp174": [ - "S142L" - ], - "OPG024": [ - "S41L" - ], - "OPG136": [ - "S748F" - ] - }, - "labels": { - "aa": "NBT03_gp174: S142L; OPG024: S41L; OPG136: S748F" - } - } - } - ] - }, - { - "name": "NODE_0000149", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150566A", - "-150567T", - "G173727A" - ] - } - }, - "children": [ - { - "name": "MPX/PT0122/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "MPX/PT0122/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP245355" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-15" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G11267A", - "G18540A", - "-150563A", - "-150564T", - "-150565G" - ], - "OPG023": [ - "S545L" - ], - "OPG031": [ - "R97W" - ] - }, - "labels": { - "aa": "OPG023: S545L; OPG031: R97W" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI889", - "node_attrs": { - "div": 4, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI889" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773508" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C104608T", - "G150550-" - ], - "OPG123": [ - "D155N" - ] - }, - "labels": { - "aa": "OPG123: D155N" - } - } - } - ] - }, - { - "name": "NODE_0000150", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C22740T", - "C38937T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG056": [ - "R33Q" - ] - }, - "labels": { - "aa": "OPG056: R33Q" - } - }, - "children": [ - { - "name": "Monkeypox/PT0531/2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0531/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555602" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-19" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6376A", - "G136834A", - "G186423A" - ], - "OPG210": [ - "E1690K" - ] - }, - "labels": { - "aa": "OPG210: E1690K" - } - } - }, - { - "name": "Monkeypox/PT0570/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0570/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555641" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-02" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G74362A", - "A136537-", - "T136538-", - "C136539-", - "A136540-", - "T136541-", - "C136542-", - "A136543-", - "T136544-", - "C136545-", - "A136546-", - "T136547-", - "C136548-", - "A136549-", - "T136550-", - "C136551-", - "A136552-", - "T136553-", - "C136554-", - "T136555-", - "A136556-", - "T136557-", - "G136558-", - "A136559-", - "T136560-", - "C177240T" - ], - "OPG094": [ - "A195T" - ], - "OPG153": [ - "I370-", - "I371-", - "D372-", - "D373-", - "D374-", - "D375-", - "D376-", - "D377-" - ], - "OPG205": [ - "Q529*" - ] - }, - "labels": { - "aa": "OPG094: A195T; OPG153: I370-, I371-, D372-, D373-, D374-, D375-, D376-, D377-; OPG205: Q529*" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000151", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C25644T" - ] - }, - "labels": { - "clade": "B.1.7" - } - }, - "children": [ - { - "name": "Monkeypox/PT0031/2022", - "node_attrs": { - "div": 1, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0031/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON843170" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-26" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV_UK_2022_9000078", - "node_attrs": { - "div": 1, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPXV_UK_2022_9000078" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205081" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-14" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV_UK_2022_9000138", - "node_attrs": { - "div": 2, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPXV_UK_2022_9000138" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205103" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-06" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C12842T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG023": [ - "R20K" - ] - }, - "labels": { - "aa": "OPG023: R20K" - } - } - }, - { - "name": "MPXV_UK_2022_9000143", - "node_attrs": { - "div": 1, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPXV_UK_2022_9000143" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205106" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-16" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV_UK_2022_9000192", - "node_attrs": { - "div": 2, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPXV_UK_2022_9000192" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205137" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-05" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G53441A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG071": [ - "S333L" - ] - }, - "labels": { - "aa": "OPG071: S333L" - } - } - }, - { - "name": "MPX_GGr0lD_9000276", - "node_attrs": { - "div": 2, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_GGr0lD_9000276" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415238" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C39935T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196603A" - ] - } - } - }, - { - "name": "MPX/Human/USA/CA-LACPHL-MA00115/2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPX/Human/USA/CA-LACPHL-MA00115/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP539900" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-14" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C1735T", - "C52883T", - "C74175T", - "G86336A", - "C87677T", - "T149447C", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "G195475A" - ], - "OPG071": [ - "R519K" - ], - "OPG108": [ - "R242C" - ], - "OPG109": [ - "D591N" - ] - }, - "labels": { - "aa": "OPG071: R519K; OPG108: R242C; OPG109: D591N" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI720", - "node_attrs": { - "div": 1, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI720" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ547747" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_245/Belgium/2022", - "node_attrs": { - "div": 2, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_245/Belgium/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR095063" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-16" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G105860A", - "T149487-", - "A149488-", - "C149489-", - "G149490-", - "T149491-", - "T149492-", - "G149493-", - "A149494-", - "A149495-", - "C149496-", - "A149497-", - "A149498-", - "G149499-", - "T149500-", - "C149501-", - "C149502-", - "A149503-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG175": [ - "Y16-", - "V17-", - "E18-", - "Q19-", - "V20-", - "H21X", - "*126X" - ] - }, - "labels": { - "aa": "OPG175: Y16-, V17-, E18-, Q19-, V20-, H21X, *126X" - } - } - }, - { - "name": "NODE_0000152", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C14077T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - }, - "children": [ - { - "name": "MPXV_UK_2022_9000093", - "node_attrs": { - "div": 4, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPXV_UK_2022_9000093" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205084" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-30" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C4529T", - "G155585A", - "G192681A" - ], - "OPG003": [ - "D27N" - ] - }, - "labels": { - "aa": "OPG003: D27N" - } - } - }, - { - "name": "MPX_cmjxZM_9000205", - "node_attrs": { - "div": 2, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_cmjxZM_9000205" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415186" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000153", - "node_attrs": { - "div": 5, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C66249T", - "C88644A", - "C104134T", - "C112638T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG109": [ - "K268N" - ], - "OPG123": [ - "A313T" - ] - }, - "labels": { - "aa": "OPG109: K268N; OPG123: A313T" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI274", - "node_attrs": { - "div": 5, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI274" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP263628" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "9000400", - "node_attrs": { - "div": 7, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "9000400" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536778" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G69081A", - "A136513-", - "T136514-", - "C136515-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "G186489A", - "A196604-" - ], - "OPG153": [ - "D385-" - ], - "OPG210": [ - "D1712N" - ] - }, - "labels": { - "aa": "OPG153: D385-; OPG210: D1712N" - } - } - } - ] - }, - { - "name": "NODE_0000154", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G180608A" - ], - "OPG209": [ - "E31K" - ] - }, - "labels": { - "aa": "OPG209: E31K" - } - }, - "children": [ - { - "name": "9000399", - "node_attrs": { - "div": 2, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "9000399" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536777" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "PrEV_case_2", - "node_attrs": { - "div": 9, - "author": { - "author": "Berens-Riha,N., De Block,T., Rutgers,J., Van Gestel,L., Hens,M., Kenyon,C., Soentjens,P., Van Griensven,J., Brosius,I., Arien,K., Van Esbroeck,M., Rezende,A.M., Vercauteren,K.", - "value": "Berens-Riha,N., De Block,T., Rutgers,J., Van Gestel,L., Hens,M., Kenyon,C., Soentjens,P., Van Griensven,J., Brosius,I., Arien,K., Van Esbroeck,M., Rezende,A.M., Vercauteren,K." - }, - "strain_original": { - "value": "PrEV_case_2" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP727822" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-02" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T348-", - "G349-", - "G350-", - "A351-", - "T352-", - "T353-", - "C11401T", - "C33964T", - "C36267T", - "C57173T", - "G110285A", - "T133078-", - "C144366T", - "A174924T", - "A188349-", - "G195316A" - ], - "OPG052": [ - "R11Q" - ], - "OPG055": [ - "D273N" - ] - }, - "labels": { - "aa": "OPG052: R11Q; OPG055: D273N" - } - } - } - ] - }, - { - "name": "NODE_0000155", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G50034A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG069": [ - "E17K" - ] - }, - "labels": { - "aa": "OPG069: E17K" - } - }, - "children": [ - { - "name": "NY-NYCPHL-000067", - "node_attrs": { - "div": 3, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000067" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469026" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-14" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G169350A", - "G188710A" - ] - } - } - }, - { - "name": "NY-NYCPHL-001112", - "node_attrs": { - "div": 5, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-001112" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469283" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-05" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G74200A", - "T103224A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "G189451A" - ], - "OPG005": [ - "V85M" - ], - "OPG094": [ - "D141N" - ], - "OPG123": [ - "D616V" - ] - }, - "labels": { - "aa": "OPG005: V85M; OPG094: D141N; OPG123: D616V" - } - } - } - ] - }, - { - "name": "NODE_0000156", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C148771T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG174": [ - "D209N" - ] - }, - "labels": { - "aa": "OPG174: D209N" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI043", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI043" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON755249" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Germany/2022/RKI206", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI206" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP215243" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C139055T" - ], - "OPG156": [ - "E119K" - ] - }, - "labels": { - "aa": "OPG156: E119K" - } - } - }, - { - "name": "NODE_0000157", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G114316A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A" - ], - "OPG133": [ - "H461Y" - ] - }, - "labels": { - "aa": "OPG133: H461Y" - } - }, - "children": [ - { - "name": "MPXV/UZ_REGA_197/Belgium/2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_197/Belgium/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR087006" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-03" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C12637T", - "G53377A", - "T133078-", - "C178569T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "C182707T" - ], - "OPG210": [ - "S451F" - ] - }, - "labels": { - "aa": "OPG210: S451F" - } - } - }, - { - "name": "NODE_0000158", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G152437A" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI631", - "node_attrs": { - "div": 5, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI631" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ159026" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150547A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "G187677A" - ] - } - } - }, - { - "name": "INMI-19442022", - "node_attrs": { - "div": 4, - "author": { - "author": "Rueca,M., Tucci,F.G., Mazzotta,V., Gramigna,G., Gruber,C.E.M., Fabeni,L., Giombini,E., Matusali,G., Pinnetti,C., Mariano,A., Butera,O., Specchiarello,E., Mondi,A., Lanini,S., Carletti,F., Girardi,E., Vaia,F., Nicastri,E., Antinori,A., Maggi,F.", - "value": "Rueca,M., Tucci,F.G., Mazzotta,V., Gramigna,G., Gruber,C.E.M., Fabeni,L., Giombini,E., Matusali,G., Pinnetti,C., Mariano,A., Butera,O., Specchiarello,E., Mondi,A., Lanini,S., Carletti,F., Girardi,E., Vaia,F., Nicastri,E., Antinori,A., Maggi,F." - }, - "strain_original": { - "value": "INMI-19442022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute for Infectious Diseases \"L. Spallanzani\" - IRCCS, Laboratory of Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ627928" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Italy" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-14" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A586-", - "A587-", - "A588-", - "-594T", - "A196599-", - "C196600-", - "-196602A" - ] - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000159", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C57173T", - "C142797T" - ], - "OPG164": [ - "S7L" - ] - }, - "labels": { - "aa": "OPG164: S7L" - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-4112/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Griffiths,E., Jolly,G., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Griffiths,E., Jolly,G., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-4112/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP279036" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-30" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "hMPXV/USA/NC-UNC-0003/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Deanhardt,B., Miller,M., Wang,J.R.", - "value": "Deanhardt,B., Miller,M., Wang,J.R." - }, - "strain_original": { - "value": "hMPXV/USA/NC-UNC-0003/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "University of North Carolina at Chapel Hill, Department of Genetics" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP480404" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-04" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "C74733T", - "C102889T", - "-133164C", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196601A", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00361/2022", - "node_attrs": { - "div": 9, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00361/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP920699" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-31" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G105325A", - "C108658T", - "G111379A", - "C149889T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G165395A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "G184244A" - ], - "OPG124": [ - "S215F" - ], - "OPG130": [ - "S175L" - ], - "OPG190": [ - "E92K" - ] - }, - "labels": { - "aa": "OPG124: S215F; OPG130: S175L; OPG190: E92K" - } - } - }, - { - "name": "MD_NIDDL_54679", - "node_attrs": { - "div": 5, - "author": { - "author": "Voegtly,L.J., Paskey,A.C., Rice,G.K., Chitty,J.A., Sugiharto,V., Chen,H.-W., Cer,R.Z., Malagon,F., Bishop-Lilly,K.A.", - "value": "Voegtly,L.J., Paskey,A.C., Rice,G.K., Chitty,J.A., Sugiharto,V., Chen,H.-W., Cer,R.Z., Malagon,F., Bishop-Lilly,K.A." - }, - "strain_original": { - "value": "MD_NIDDL_54679" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Naval Medical Research Center Biological Defense Research Directorate, Bioinformatics and Genomics Department" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ706777" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-01" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G10677A", - "C168651T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG022": [ - "S61L" - ], - "OPG195": [ - "S141L" - ] - }, - "labels": { - "aa": "OPG022: S61L; OPG195: S141L" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00486/2023", - "node_attrs": { - "div": 11, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00486/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ918697" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-02-18" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C55036T", - "G73789A", - "C96914T", - "C136435T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G158254A", - "C166803T", - "C170381T", - "G178559A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-" - ], - "NBT03_gp052": [ - "E36K" - ], - "OPG094": [ - "G4R" - ], - "OPG117": [ - "S289L" - ], - "OPG192": [ - "P25S" - ], - "OPG198": [ - "S115L" - ] - }, - "labels": { - "aa": "NBT03_gp052: E36K; OPG094: G4R; OPG117: S289L; OPG192: P25S; OPG198: S115L" - } - } - }, - { - "name": "MPXV_USA_2022_NC0003", - "node_attrs": { - "div": 4, - "author": { - "author": "Li,C.M.", - "value": "Li,C.M." - }, - "strain_original": { - "value": "MPXV_USA_2022_NC0003" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR209323" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-12-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G62268A", - "A136513-", - "T136514-", - "C136515-", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A196604-" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - } - ] - }, - { - "name": "NODE_0000160", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G120241A", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG137": [ - "D214N" - ] - }, - "labels": { - "aa": "OPG137: D214N" - } - }, - "children": [ - { - "name": "Monkeypox/MX-UANL001/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Galan-Huerta,K.A., Paz-Infanzon,M., Ruiz-Higareda,A.F., Nuzzolo-Shihadeh,L., Camacho-Ortiz,A., Bocanegra-Ibarias,P., Rivas-Estilla,A.M., Zacarias-Villarreal,D., Yamallel-Ortega,L.A., Guerrero-Putz,M.D., Ocampo-Candiani,J.", - "value": "Galan-Huerta,K.A., Paz-Infanzon,M., Ruiz-Higareda,A.F., Nuzzolo-Shihadeh,L., Camacho-Ortiz,A., Bocanegra-Ibarias,P., Rivas-Estilla,A.M., Zacarias-Villarreal,D., Yamallel-Ortega,L.A., Guerrero-Putz,M.D., Ocampo-Candiani,J." - }, - "strain_original": { - "value": "Monkeypox/MX-UANL001/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Universidad Autonoma de Nuevo Leon - Facultad de Medicina, Centro de Investigacion e Innovacion en Virologia Medica" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON911481" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Mexico" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-28" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G57088A", - "C127530T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "T168120C", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196601A", - "-196602A", - "-196603A" - ], - "OPG074": [ - "S13L" - ], - "OPG149": [ - "S112L" - ], - "OPG193": [ - "F263L" - ] - }, - "labels": { - "aa": "OPG074: S13L; OPG149: S112L; OPG193: F263L" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI361", - "node_attrs": { - "div": 4, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI361" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP484682" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-133078T", - "-133079T", - "-133080T", - "-133081T", - "-133082T", - "C168226T", - "C175467T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI544", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI544" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP715824" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-133078T", - "-133079T", - "-133080T", - "-133081T", - "-133082T" - ] - } - } - }, - { - "name": "MPXV_USA_2022_DE0001", - "node_attrs": { - "div": 2, - "author": { - "author": "Gigante,C., Moreno-Gorrin,C., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Miller,H., Li,Y.", - "value": "Gigante,C., Moreno-Gorrin,C., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Miller,H., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_DE0001" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP881944" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A136513-", - "T136514-", - "C136515-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "NY-NYCPHL-001175", - "node_attrs": { - "div": 4, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-001175" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469310" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-07" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C13462T", - "C125660T", - "A136513-", - "T136514-", - "C136515-", - "G150550-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG025": [ - "M602I" - ], - "OPG147": [ - "D110N" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG025: M602I; OPG147: D110N; OPG153: D385-" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI833", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI833" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773452" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI876", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI876" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773495" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000161", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G63147A" - ] - } - }, - "children": [ - { - "name": "MPX_vSkiJH_9000281", - "node_attrs": { - "div": 6, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_vSkiJH_9000281" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415243" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C15004T", - "C101845T", - "C155483T", - "G177780A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG121": [ - "S19F" - ], - "OPG205": [ - "E709K" - ] - }, - "labels": { - "aa": "OPG121: S19F; OPG205: E709K" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI396", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI396" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP523999" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A136513-", - "T136514-", - "C136515-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-196603A" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "NODE_0000162", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G10224A", - "G129761A", - "T143625A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C177847T", - "-196603A" - ], - "OPG021": [ - "R213Q" - ], - "OPG151": [ - "D280N" - ], - "OPG165": [ - "I37N" - ], - "OPG205": [ - "S731L" - ] - }, - "labels": { - "aa": "OPG021: R213Q; OPG151: D280N; OPG165: I37N; OPG205: S731L" - } - }, - "children": [ - { - "name": "NICD-SVPL223", - "node_attrs": { - "div": 6, - "author": { - "author": "Chan,W.Y., Mtshali,S., Grobbelaar,A., Moolla,N., Mohale,T., Lowe,M., Du Plessis,M., Ismail,A., Weyer,J.", - "value": "Chan,W.Y., Mtshali,S., Grobbelaar,A., Moolla,N., Mohale,T., Lowe,M., Du Plessis,M., Ismail,A., Weyer,J." - }, - "strain_original": { - "value": "NICD-SVPL223" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "National Institute for Communicable Disease, Sequencing Core Facility" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON918611" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "South Africa" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-20" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T" - ] - } - } - }, - { - "name": "NICD-SVPL232", - "node_attrs": { - "div": 6, - "author": { - "author": "Chan,W.Y., Mtshali,P.S., Grobbelaar,A., Moolla,N., Mohale,T., Lowe,M., Du Plessis,M., Ismail,A., Weyer,J.", - "value": "Chan,W.Y., Mtshali,P.S., Grobbelaar,A., Moolla,N., Mohale,T., Lowe,M., Du Plessis,M., Ismail,A., Weyer,J." - }, - "strain_original": { - "value": "NICD-SVPL232" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "National Institute for Communicable Disease, Sequencing core facility" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON927248" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "South Africa" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-24" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A196603C" - ] - } - } - } - ] - }, - { - "name": "NODE_0000163", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C70780T" - ] - } - }, - "children": [ - { - "name": "MPXV_UK_2022_9000106", - "node_attrs": { - "div": 3, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPXV_UK_2022_9000106" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205094" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-14" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "NODE_0000164", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C190668T" - ], - "NBT03_gp174": [ - "R87*" - ] - }, - "labels": { - "aa": "NBT03_gp174: R87*" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI140", - "node_attrs": { - "div": 6, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI140" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON959149" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A63147G", - "G156469A" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI240", - "node_attrs": { - "div": 6, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI240" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP215225" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T25644C", - "C32909T" - ] - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000165", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G42504A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - }, - "children": [ - { - "name": "PatientMPXV", - "node_attrs": { - "div": 3, - "author": { - "author": "Seang,S., Burrel,S., Todesco,E., Leducq,V., Monsel,G., Le Pluart,D., Cordevant,C., Pourcher,V., Palich,R., Charpentier,C.", - "value": "Seang,S., Burrel,S., Todesco,E., Leducq,V., Monsel,G., Le Pluart,D., Cordevant,C., Pourcher,V., Palich,R., Charpentier,C." - }, - "strain_original": { - "value": "PatientMPXV" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "APHP Pitie Salpetriere SU, Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP204840" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-10" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G163250A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A196604-", - "A196605-", - "A196606-" - ] - } - } - }, - { - "name": "Monkeypox/PT0225/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0225/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP324535" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-22" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G186537A" - ], - "OPG210": [ - "E1728K" - ] - }, - "labels": { - "aa": "OPG210: E1728K" - } - } - }, - { - "name": "Monkeypox/PT0379/2022", - "node_attrs": { - "div": 2, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0379/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555475" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-06" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0479/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0479/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555558" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-09" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C134850T", - "C159741T", - "A196604-" - ] - } - } - }, - { - "name": "NODE_0000166", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C5292T", - "G74267A", - "C115870T", - "A161784T", - "G191918A" - ], - "NBT03_gp175": [ - "D289N" - ], - "OPG015": [ - "D289N" - ], - "OPG094": [ - "R163Q" - ] - }, - "labels": { - "aa": "NBT03_gp175: D289N; OPG015: D289N; OPG094: R163Q" - } - }, - "children": [ - { - "name": "Monkeypox/PT0237/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0237/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP324545" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-22" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000167", - "node_attrs": { - "div": 7, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G11924A" - ], - "OPG023": [ - "S326L" - ] - }, - "labels": { - "aa": "OPG023: S326L" - } - }, - "children": [ - { - "name": "MPX/PT0077/2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "MPX/PT0077/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP245331" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-28" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0493/2022", - "node_attrs": { - "div": 9, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0493/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555568" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-11" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G125379A", - "G176342A" - ], - "OPG145": [ - "R478K" - ] - }, - "labels": { - "aa": "OPG145: R478K" - } - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000168", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G186165A" - ], - "OPG210": [ - "D1604N" - ] - }, - "labels": { - "aa": "OPG210: D1604N", - "clade": "B.1.2" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI124", - "node_attrs": { - "div": 1, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI124" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON929079" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPX_gOirGi_9000215", - "node_attrs": { - "div": 1, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_gOirGi_9000215" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415193" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPX_fZLVcc_9000229", - "node_attrs": { - "div": 1, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_fZLVcc_9000229" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415204" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI422", - "node_attrs": { - "div": 2, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI422" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP594186" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G832A", - "G94840A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C196378T" - ], - "OPG115": [ - "E61K" - ] - }, - "labels": { - "aa": "OPG115: E61K" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI673", - "node_attrs": { - "div": 1, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI673" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ274892" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A152668-", - "T152680-" - ] - } - } - }, - { - "name": "NODE_0000169", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C20992T", - "G143789A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A" - ], - "OPG036": [ - "D25N" - ], - "OPG165": [ - "D92N" - ] - }, - "labels": { - "aa": "OPG036: D25N; OPG165: D92N" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI569", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI569" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP764627" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000170", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C29229T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG045": [ - "D12N" - ] - }, - "labels": { - "aa": "OPG045: D12N" - } - }, - "children": [ - { - "name": "MPXV_UK_2022_9000101", - "node_attrs": { - "div": 7, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPXV_UK_2022_9000101" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205089" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-09" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C147168T", - "G149561A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "G182486A" - ], - "OPG171": [ - "L61F" - ] - }, - "labels": { - "aa": "OPG171: L61F" - } - } - }, - { - "name": "9000390", - "node_attrs": { - "div": 5, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "9000390" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536768" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150567T", - "G165371A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG190": [ - "E84K" - ] - }, - "labels": { - "aa": "OPG190: E84K" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000171", - "node_attrs": { - "div": 2, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "C188391T" - ] - } - }, - "children": [ - { - "name": "MPXV_UK_2022_9000092", - "node_attrs": { - "div": 2, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPXV_UK_2022_9000092" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205083" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-25" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV_UK_2022_9000097", - "node_attrs": { - "div": 2, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPXV_UK_2022_9000097" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205086" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-06" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Germany/2022/RKI228", - "node_attrs": { - "div": 4, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI228" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP215256" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C22880T", - "G62253A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ], - "OPG038": [ - "E94K" - ] - }, - "labels": { - "aa": "OPG038: E94K" - } - } - }, - { - "name": "hMPXV/USA/NC-UNC-0019/2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Deanhardt,B., Miller,M., Wang,J.R.", - "value": "Deanhardt,B., Miller,M., Wang,J.R." - }, - "strain_original": { - "value": "hMPXV/USA/NC-UNC-0019/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "University of North Carolina at Chapel Hill, Department of Genetics" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP480418" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-29" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "A31053G", - "G32405A", - "C121067T", - "G154135A", - "C173533A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG047": [ - "C48R" - ], - "OPG180": [ - "E482K" - ] - }, - "labels": { - "aa": "OPG047: C48R; OPG180: E482K" - } - } - }, - { - "name": "9000408", - "node_attrs": { - "div": 2, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "9000408" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536784" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - }, - { - "name": "9000416", - "node_attrs": { - "div": 2, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "9000416" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536790" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "A196604-" - ] - } - } - }, - { - "name": "Slovenia-MPXV-42-2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "strain_original": { - "value": "Slovenia-MPXV-42-2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605583" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A138-", - "-595T", - "C17614A", - "C27187T", - "G111484A", - "G147305A", - "C159401A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG030": [ - "V74L" - ], - "OPG043": [ - "D257N" - ], - "OPG130": [ - "T140I" - ], - "OPG185": [ - "S162Y" - ] - }, - "labels": { - "aa": "OPG030: V74L; OPG043: D257N; OPG130: T140I; OPG185: S162Y" - } - } - }, - { - "name": "MPXV22/human/USA-OK-273", - "node_attrs": { - "div": 4, - "author": { - "author": "Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., O'Dell,J.X., Mannell,M., Wiley,M.R., Cross,S.T.", - "value": "Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., O'Dell,J.X., Mannell,M., Wiley,M.R., Cross,S.T." - }, - "strain_original": { - "value": "MPXV22/human/USA-OK-273" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP650031" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-07" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "G51378A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G158721A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-196601A", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "MPXV_USA_2022_UT0004", - "node_attrs": { - "div": 4, - "author": { - "author": "Gigante,C., Murray,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burroughs,A.B., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Atkinson,A., Li,Y.", - "value": "Gigante,C., Murray,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burroughs,A.B., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Atkinson,A., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_UT0004" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ320444" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C156429T", - "G167070A", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "A196604-" - ], - "OPG192": [ - "D114N" - ] - }, - "labels": { - "aa": "OPG192: D114N" - } - } - }, - { - "name": "MPXV_USA_2022_NY0019", - "node_attrs": { - "div": 2, - "author": { - "author": "Gigante,C., Ruiz,V., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Wang,J., Li,Y.", - "value": "Gigante,C., Ruiz,V., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Wang,J., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_NY0019" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ320462" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-" - ] - } - } - }, - { - "name": "MPXV_USA_2022_TN0012", - "node_attrs": { - "div": 3, - "author": { - "author": "Gigante,C., Thomas,L., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Dunn,J., Li,Y.", - "value": "Gigante,C., Thomas,L., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Dunn,J., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_TN0012" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ320506" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G67225A", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-" - ], - "OPG085": [ - "S436L" - ] - }, - "labels": { - "aa": "OPG085: S436L" - } - } - }, - { - "name": "Monkeypox virus/Human/USA/CA-LACPHL-MA00389/2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "Monkeypox virus/Human/USA/CA-LACPHL-MA00389/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ330996" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-12-12" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G569-", - "A570-", - "A571-", - "G2126A", - "C64132T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C154736T", - "C162837T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "G183791A", - "C195084T" - ], - "OPG002": [ - "S209L" - ], - "OPG083": [ - "M195I" - ], - "OPG181": [ - "P109S" - ] - }, - "labels": { - "aa": "OPG002: S209L; OPG083: M195I; OPG181: P109S" - } - } - }, - { - "name": "Monkeypox virus/Human/USA/CA-LACPHL-MA00390/2022", - "node_attrs": { - "div": 6, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "Monkeypox virus/Human/USA/CA-LACPHL-MA00390/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ330997" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-12-14" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G4248A", - "C100938T", - "G146665A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G159103A", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "C192962T" - ], - "OPG120": [ - "E271K" - ], - "OPG185": [ - "D63N" - ] - }, - "labels": { - "aa": "OPG120: E271K; OPG185: D63N" - } - } - }, - { - "name": "NY-NYCPHL-000648", - "node_attrs": { - "div": 4, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000648" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ419052" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-16" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C41096T", - "G94653A", - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG060": [ - "M29I" - ] - }, - "labels": { - "aa": "OPG060: M29I" - } - } - }, - { - "name": "NY-NYCPHL-000284", - "node_attrs": { - "div": 4, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000284" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468854" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-02" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C20296T", - "C99441T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG035": [ - "D37N" - ] - }, - "labels": { - "aa": "OPG035: D37N" - } - } - }, - { - "name": "NY-NYCPHL-000697", - "node_attrs": { - "div": 6, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000697" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469214" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-16" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C15582T", - "C141442T", - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G176142A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "C189174T" - ], - "OPG161": [ - "S114L" - ], - "OPG205": [ - "E163K" - ] - }, - "labels": { - "aa": "OPG161: S114L; OPG205: E163K" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00461/2023", - "node_attrs": { - "div": 6, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00461/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503838" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-01-20" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G49266A", - "C88489T", - "G98119A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "C188491T" - ], - "OPG068": [ - "D356N" - ], - "OPG109": [ - "R320K" - ], - "OPG117": [ - "E691K" - ] - }, - "labels": { - "aa": "OPG068: D356N; OPG109: R320K; OPG117: E691K" - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-012937/2023", - "node_attrs": { - "div": 10, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-012937/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ979625" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-01-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A63108T", - "G77907A", - "G92718A", - "C136554T", - "G148238A", - "C167676T", - "G180523A", - "G180531A", - "G180827A" - ], - "OPG099": [ - "M81I" - ], - "OPG113": [ - "E330K" - ], - "OPG153": [ - "D372N" - ], - "OPG173": [ - "D68N" - ], - "OPG193": [ - "H115Y" - ], - "OPG209": [ - "G5E", - "E104K" - ] - }, - "labels": { - "aa": "OPG099: M81I; OPG113: E330K; OPG153: D372N; OPG173: D68N; OPG193: H115Y; OPG209: G5E, E104K" - } - } - }, - { - "name": "MPXV/UZ_REGA_164/Belgium/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_164/Belgium/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR086973" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-27" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G135633A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - }, - { - "name": "NODE_0000172", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6771A", - "C99166T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/ON/RKI312", - "node_attrs": { - "div": 4, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI312" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP494262" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI461", - "node_attrs": { - "div": 4, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI461" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP615335" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000173", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C27730T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG043": [ - "D76N" - ] - }, - "labels": { - "aa": "OPG043: D76N" - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00295/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00295/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP890528" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-01" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G176439A", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ], - "OPG205": [ - "D262N" - ] - }, - "labels": { - "aa": "OPG205: D262N" - } - } - }, - { - "name": "NY-NYCPHL-000184", - "node_attrs": { - "div": 3, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000184" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468822" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-30" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - } - ] - }, - { - "name": "NODE_0000174", - "node_attrs": { - "div": 10, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T11371C", - "G34303A", - "C85322T", - "G92048A", - "G123119A", - "G129583A", - "C140931T", - "C178378T" - ], - "OPG053": [ - "P130S" - ], - "OPG143": [ - "S66L" - ] - }, - "labels": { - "aa": "OPG053: P130S; OPG143: S66L" - } - }, - "children": [ - { - "name": "9000231", - "node_attrs": { - "div": 10, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "9000231" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP413713" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPX_TcUINH_9000230", - "node_attrs": { - "div": 11, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_TcUINH_9000230" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415205" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C153104T" - ], - "OPG180": [ - "S138F" - ] - }, - "labels": { - "aa": "OPG180: S138F" - } - } - }, - { - "name": "MPX_cbQgLw_9000299", - "node_attrs": { - "div": 10, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_cbQgLw_9000299" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415253" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000175", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G45781A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG064": [ - "H40Y" - ] - }, - "labels": { - "aa": "OPG064: H40Y" - } - }, - "children": [ - { - "name": "Monkeypox/PT0554/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0554/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555625" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-30" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G29102A", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ], - "OPG045": [ - "S54L" - ] - }, - "labels": { - "aa": "OPG045: S54L" - } - } - }, - { - "name": "MPXV_USA_2022_CA0016", - "node_attrs": { - "div": 6, - "author": { - "author": "Gigante,C., Ventura,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nash,J., Li,Y.", - "value": "Gigante,C., Ventura,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nash,J., Li,Y." - }, - "strain_original": { - "value": "MPXV_USA_2022_CA0016" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ427133" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G33695A", - "G37974A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150565-", - "A150566-", - "T150567-", - "C157380T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "-196603A" - ], - "OPG056": [ - "S354L" - ] - }, - "labels": { - "aa": "OPG056: S354L" - } - } - }, - { - "name": "NY-NYCPHL-000149", - "node_attrs": { - "div": 3, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000149" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469153" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-26" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - } - ] - }, - { - "name": "NODE_0000176", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T26669C", - "G96073A", - "G115235A", - "C125294T" - ], - "OPG117": [ - "D9N" - ] - }, - "labels": { - "aa": "OPG117: D9N" - } - }, - "children": [ - { - "name": "BOL-UNIMOL-MPX-293428-L", - "node_attrs": { - "div": 6, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "strain_original": { - "value": "BOL-UNIMOL-MPX-293428-L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP959060" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-29" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000177", - "node_attrs": { - "div": 7, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C135868T" - ] - } - }, - "children": [ - { - "name": "BOL-UNIMOL-MPX-293613-L", - "node_attrs": { - "div": 7, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "strain_original": { - "value": "BOL-UNIMOL-MPX-293613-L" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP959061" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-11" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Germany/2022/RKI632", - "node_attrs": { - "div": 8, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI632" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ159027" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-11-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G77052A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000178", - "node_attrs": { - "div": 8, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G8638A", - "C21548T", - "C47820T", - "C68218T", - "C188236T", - "C188339T" - ], - "OPG037": [ - "D296N" - ], - "OPG085": [ - "R105Q" - ] - }, - "labels": { - "aa": "OPG037: D296N; OPG085: R105Q" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-042823/2023", - "node_attrs": { - "div": 9, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-042823/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ979621" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-04-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C102741T" - ], - "OPG122": [ - "S105L" - ] - }, - "labels": { - "aa": "OPG122: S105L" - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-041886/2023", - "node_attrs": { - "div": 8, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-041886/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ979622" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-04-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "T133079-" - ] - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-028492/2023", - "node_attrs": { - "div": 10, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-028492/2023" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ979624" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-02-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G12239A", - "G12488A", - "-196603A" - ], - "OPG023": [ - "S138L", - "S221F" - ] - }, - "labels": { - "aa": "OPG023: S138L, S221F" - } - } - } - ] - }, - { - "name": "NODE_0000179", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T157527C", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ] - } - }, - "children": [ - { - "name": "MPXV_UK_2022_9000187", - "node_attrs": { - "div": 3, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPXV_UK_2022_9000187" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205132" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-28" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI315", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI315" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP355573" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A188349-" - ] - } - } - }, - { - "name": "Monkeypox/PT0387/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0387/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555483" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-12" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G154098A" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI590", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI590" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP837352" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI825", - "node_attrs": { - "div": 4, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI825" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773444" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C24172T" - ] - } - } - }, - { - "name": "NODE_0000180", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G177872A" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI554", - "node_attrs": { - "div": 5, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI554" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP715834" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C11100T" - ], - "OPG023": [ - "E601K" - ] - }, - "labels": { - "aa": "OPG023: E601K" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI893", - "node_attrs": { - "div": 7, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI893" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773512" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150087A", - "C156429T", - "C156509T" - ] - } - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000181", - "node_attrs": { - "div": 1, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "G190660A" - ], - "NBT03_gp174": [ - "R84K" - ] - }, - "labels": { - "aa": "NBT03_gp174: R84K", - "clade": "B.1.3" - } - }, - "children": [ - { - "name": "MPxV/Prague_001/2022/flye_medaka", - "node_attrs": { - "div": 1, - "author": { - "author": "Chmel,M., Pajer,P., Nagy,A., Zlamal,M., Jirincova,H., Dresler,J., Bartos,O.", - "value": "Chmel,M., Pajer,P., Nagy,A., Zlamal,M., Jirincova,H., Dresler,J., Bartos,O." - }, - "strain_original": { - "value": "MPxV/Prague_001/2022/flye_medaka" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Military Heatlh Institute, Military Heatlh Institute in Prague" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON983168" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Czech Republic" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-04-28" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T80841-" - ], - "OPG104": [ - "N60X", - "*134X" - ] - }, - "labels": { - "aa": "OPG104: N60X, *134X" - } - } - }, - { - "name": "9000432", - "node_attrs": { - "div": 3, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "9000432" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536804" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C6423A", - "C135775T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T190786-", - "A196604-" - ], - "NBT03_gp174": [ - "I126X", - "*177X" - ] - }, - "labels": { - "aa": "NBT03_gp174: I126X, *177X" - } - } - }, - { - "name": "PrEV_case_1", - "node_attrs": { - "div": 1, - "author": { - "author": "Berens-Riha,N., De Block,T., Rutgers,J., Van Gestel,L., Hens,M., Kenyon,C., Soentjens,P., Van Griensven,J., Brosius,I., Arien,K., Van Esbroeck,M., Rezende,A.M., Vercauteren,K.", - "value": "Berens-Riha,N., De Block,T., Rutgers,J., Van Gestel,L., Hens,M., Kenyon,C., Soentjens,P., Van Griensven,J., Brosius,I., Arien,K., Van Esbroeck,M., Rezende,A.M., Vercauteren,K." - }, - "strain_original": { - "value": "PrEV_case_1" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP727821" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-27" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "G179020-", - "T179021-", - "C179022-", - "G179023-", - "A179024-", - "G179025-", - "T179026-", - "A179027-", - "T179028-", - "G179029-", - "A179030-", - "A179031-", - "T179032-", - "A179033-", - "C179034-", - "G179035-", - "G179036-", - "A179037-", - "G179038-", - "T179039-", - "A179040-", - "C179041-", - "A179042-", - "A179043-", - "A179044-", - "C179045-", - "A179046-", - "T179047-", - "A179048-", - "A179049-", - "A179050-", - "C179051-" - ] - } - } - }, - { - "name": "NY-NYCPHL-000118", - "node_attrs": { - "div": 4, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000118" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ504398" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-22" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C2315T", - "C102077T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150566A", - "-150567T", - "C170204T", - "G194895A" - ], - "OPG002": [ - "G146E" - ], - "OPG198": [ - "S56F" - ] - }, - "labels": { - "aa": "OPG002: G146E; OPG198: S56F" - } - } - }, - { - "name": "NODE_0000182", - "node_attrs": { - "div": 3, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-596T", - "G55133A", - "C64426T", - "-150559G", - "-150560G", - "-150565G", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ], - "OPG074": [ - "R665C" - ] - }, - "labels": { - "aa": "OPG074: R665C" - } - }, - "children": [ - { - "name": "MPXV_FR_HCL0001_2022", - "node_attrs": { - "div": 4, - "strain_original": { - "value": "MPXV_FR_HCL0001_2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Virology, GENomique EPIdemiologique das maladies Infectieuses, France" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON622722" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-22" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C109627A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-" - ], - "OPG129": [ - "A460S" - ] - }, - "labels": { - "aa": "OPG129: A460S" - } - } - }, - { - "name": "MPXV_SI2022_S5", - "node_attrs": { - "div": 3, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "strain_original": { - "value": "MPXV_SI2022_S5" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON754986" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G143-", - "-595T", - "G150559-", - "G150560-", - "G150565-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/Spain/HUNSC_ITER_0001a/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Alcoba-Florez,J., Munoz-Barrera,A., Ciuffreda,L., Rodriguez-Perez,H., Rubio-Rodriguez,L.A., Gil-Campesino,H., Garcia-Martinez de Artola,D., Inigo-Campos,A., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C.", - "value": "Alcoba-Florez,J., Munoz-Barrera,A., Ciuffreda,L., Rodriguez-Perez,H., Rubio-Rodriguez,L.A., Gil-Campesino,H., Garcia-Martinez de Artola,D., Inigo-Campos,A., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C." - }, - "strain_original": { - "value": "MPXV/Spain/HUNSC_ITER_0001a/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON782054" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-31" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G50337A", - "A122238T", - "-133164C", - "-133165A", - "-133166A", - "-133167T", - "-133168C", - "-133169T", - "-133170T", - "-133171T", - "-133172C", - "-133173T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "A169759G", - "A193392G", - "T193688C", - "T194099C", - "T194619C", - "T195948C", - "-196603A" - ], - "OPG001": [ - "L105S" - ], - "OPG002": [ - "F54S" - ], - "OPG003": [ - "N264D" - ], - "OPG069": [ - "G118R" - ], - "OPG143": [ - "S360T" - ] - }, - "labels": { - "aa": "OPG001: L105S; OPG002: F54S; OPG003: N264D; OPG069: G118R; OPG143: S360T" - } - } - }, - { - "name": "MPXV/Spain/HUNSC_ITER_0001b/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Alcoba-Florez,J., Munoz-Barrera,A., Ciuffreda,L., Rodriguez-Perez,H., Rubio-Rodriguez,L.A., Gil-Campesino,H., Garcia-Martinez de Artola,D., Inigo-Campos,A., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C.", - "value": "Alcoba-Florez,J., Munoz-Barrera,A., Ciuffreda,L., Rodriguez-Perez,H., Rubio-Rodriguez,L.A., Gil-Campesino,H., Garcia-Martinez de Artola,D., Inigo-Campos,A., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C." - }, - "strain_original": { - "value": "MPXV/Spain/HUNSC_ITER_0001b/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON782055" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-31" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A48265T", - "C48296G", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T" - ], - "OPG068": [ - "D22V" - ] - }, - "labels": { - "aa": "OPG068: D22V" - } - } - }, - { - "name": "hMpxV/Switzerland/ZH-UZH-IMV-3ba6449f/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Kufner,V., Ziltener,G., Zaheri,M., Schmutz,S., Audige,A., Bernasconi,O., Steiner,K., Huder,J., Shah,C., Capaul,R., Bloemberg,G., Boeni,J., Huber,M., Trkola,A.", - "value": "Kufner,V., Ziltener,G., Zaheri,M., Schmutz,S., Audige,A., Bernasconi,O., Steiner,K., Huder,J., Shah,C., Capaul,R., Bloemberg,G., Boeni,J., Huber,M., Trkola,A." - }, - "strain_original": { - "value": "hMpxV/Switzerland/ZH-UZH-IMV-3ba6449f/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Zurich, Institute of Medical Virology" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON792320" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Switzerland" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-01" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150559-", - "G150560-", - "G150565-", - "G159376A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG185": [ - "D154N" - ] - }, - "labels": { - "aa": "OPG185: D154N" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI079", - "node_attrs": { - "div": 4, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI079" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON853661" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C15947T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T" - ], - "OPG027": [ - "R144K" - ] - }, - "labels": { - "aa": "OPG027: R144K" - } - } - }, - { - "name": "MPXV_UK_2022_9000061", - "node_attrs": { - "div": 3, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPXV_UK_2022_9000061" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205067" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-27" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G150559-", - "G150560-", - "G150565-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196603A" - ] - } - } - }, - { - "name": "MPXV_UK_2022_9000188", - "node_attrs": { - "div": 4, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPXV_UK_2022_9000188" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205133" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-29" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C142545T", - "G150559-", - "G150560-", - "G150565-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196603A" - ], - "OPG163": [ - "S115F" - ] - }, - "labels": { - "aa": "OPG163: S115F" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI288", - "node_attrs": { - "div": 5, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Friesen,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Friesen,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI288" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP270477" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C12960T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "C174633T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI311", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI311" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP355570" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "A188349-" - ] - } - } - }, - { - "name": "MPX_7f1tnH_9000280", - "node_attrs": { - "div": 3, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "MPX_7f1tnH_9000280" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415242" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G150559-", - "G150560-", - "G150565-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A196604-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI405", - "node_attrs": { - "div": 4, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI405" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP524007" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A36620C", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T" - ], - "OPG055": [ - "V155G" - ] - }, - "labels": { - "aa": "OPG055: V155G" - } - } - }, - { - "name": "9000377", - "node_attrs": { - "div": 3, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "9000377" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536757" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A196604-" - ] - } - } - }, - { - "name": "Monkeypox/PT0488/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0488/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555564" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-11" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "A136513-", - "T136514-", - "C136515-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "A196604-" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "Monkeypox/PT0514/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0514/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555585" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-16" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A136513-", - "T136514-", - "C136515-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "Monkeypox/PT0562/2022", - "node_attrs": { - "div": 4, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0562/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555633" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-01" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A136513-", - "T136514-", - "C136515-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "C168066T" - ], - "OPG153": [ - "D385-" - ], - "OPG193": [ - "Q245*" - ] - }, - "labels": { - "aa": "OPG153: D385-; OPG193: Q245*" - } - } - }, - { - "name": "Slovenia-MPXV-20-2022", - "node_attrs": { - "div": 9, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "strain_original": { - "value": "Slovenia-MPXV-20-2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605562" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594A", - "-595T", - "A29748T", - "G72609A", - "G72610T", - "G72611T", - "T72614A", - "A72617C", - "C72618-", - "G72619-", - "T72620-", - "A72621-", - "T72622-", - "G150559-", - "G150560-", - "G150565-" - ], - "OPG047": [ - "*483K" - ], - "OPG092": [ - "N109X", - "T110-", - "C111G", - "K112X", - "P113N", - "*372X" - ] - }, - "labels": { - "aa": "OPG047: *483K; OPG092: N109X, T110-, C111G, K112X, P113N, *372X" - } - } - }, - { - "name": "NJ-MPXV-017-rep2", - "node_attrs": { - "div": 3, - "author": { - "author": "Palmateer,N.C.", - "value": "Palmateer,N.C." - }, - "strain_original": { - "value": "NJ-MPXV-017-rep2" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "New Jersey Department of Health, Public Health and Environmental Laboratories" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP879736" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-29" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI669", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI669" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ274888" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150559-", - "G150560-", - "G150565-", - "A152668-", - "T152680-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI670", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI670" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ274889" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150559-", - "G150560-", - "G150565-", - "A152668-", - "T152680-" - ] - } - } - }, - { - "name": "NY-NYCPHL-001089", - "node_attrs": { - "div": 4, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-001089" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469267" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-06" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "G163468A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG189": [ - "E46K" - ] - }, - "labels": { - "aa": "OPG189: E46K" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI834", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI834" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773453" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI851", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI851" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773470" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_80", - "node_attrs": { - "div": 4, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_80" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035686" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-09" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C22950T", - "T133078-", - "T133079-", - "C133161T", - "G150559-", - "G150560-", - "G150565-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_109", - "node_attrs": { - "div": 3, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_109" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035715" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-28" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "G150559-", - "G150560-", - "G150565-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "T195509-", - "A195510-", - "A195511-" - ] - } - } - }, - { - "name": "RNA", - "node_attrs": { - "div": 5, - "strain_original": { - "value": "RNA" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OX248696" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovakia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-04" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G37250A", - "C138080T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A196604-" - ], - "OPG155": [ - "E138K" - ] - }, - "labels": { - "aa": "OPG155: E138K" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI042", - "node_attrs": { - "div": 3, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI042" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON755248" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV_SI2022_S4", - "node_attrs": { - "div": 3, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "strain_original": { - "value": "MPXV_SI2022_S4" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON754985" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A27-", - "T153-", - "-595T", - "G150559-", - "G150560-", - "G150565-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPX-37/Finland/2022", - "node_attrs": { - "div": 3, - "author": { - "author": "Kant,R., Smura,T., Vauhkonen,H., Vapalahti,O.", - "value": "Kant,R., Smura,T., Vauhkonen,H., Vapalahti,O." - }, - "strain_original": { - "value": "MPX-37/Finland/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Helsinki, Department of Virology, Faculty of Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON782021" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Finland" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-24" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - }, - { - "name": "NODE_0000183", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A27-", - "T153-", - "-595T", - "G150559-", - "G150560-", - "G150565-", - "G167517A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG193": [ - "E62K" - ] - }, - "labels": { - "aa": "OPG193: E62K" - } - }, - "children": [ - { - "name": "SLO", - "node_attrs": { - "div": 4, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Skubic,C., Rozman,D., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Skubic,C., Rozman,D., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "strain_original": { - "value": "SLO" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON609725" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-23" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV_SI2022_S1_VEROE6", - "node_attrs": { - "div": 4, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "strain_original": { - "value": "MPXV_SI2022_S1_VEROE6" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON754987" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-23" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000184", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G101152A", - "G124855T", - "G141131A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T" - ], - "OPG145": [ - "E303D" - ] - }, - "labels": { - "aa": "OPG145: E303D" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI371", - "node_attrs": { - "div": 7, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI371" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP484692" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C180490G" - ] - } - } - }, - { - "name": "9000409", - "node_attrs": { - "div": 6, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "strain_original": { - "value": "9000409" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536785" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "-595T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196602A", - "-196603A" - ] - } - } - } - ] - }, - { - "name": "NODE_0000185", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C133161T", - "C157632T" - ] - } - }, - "children": [ - { - "name": "Monkeypox/PT0376/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "Monkeypox/PT0376/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555472" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-07" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "G159243A" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_165/Belgium/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_165/Belgium/2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR086974" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-27" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G41336A", - "T133078-", - "G150559-", - "G150560-", - "G150565-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - } - ] - }, - { - "name": "NODE_0000188", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "G150559-", - "G150560-", - "G150565-", - "T168120C", - "T179026-", - "A179027-", - "T179028-", - "G179029-", - "A179030-", - "A179031-", - "T179032-", - "A179033-", - "C179034-", - "G179035-", - "G179036-", - "A179037-", - "G179038-", - "T179039-", - "A179040-", - "C179041-", - "A179042-", - "A179043-", - "A179044-", - "C179045-", - "A179046-", - "T179047-", - "A179048-", - "A179049-", - "A179050-", - "C179051-", - "T179052-", - "G179053-", - "A179054-", - "A179055-", - "G179056-", - "T179057-", - "-179081A" - ], - "OPG193": [ - "F263L" - ] - }, - "labels": { - "aa": "OPG193: F263L" - } - }, - "children": [ - { - "name": "MPXV/ITM_pt_31/Belgium/27-May-2022", - "node_attrs": { - "div": 4, - "author": { - "author": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., Van den Bossche,D., Florence,E., Rezende,A.M., Vercauteren,K., Van Esbroeck,M.", - "value": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., Van den Bossche,D., Florence,E., Rezende,A.M., Vercauteren,K., Van Esbroeck,M." - }, - "strain_original": { - "value": "MPXV/ITM_pt_31/Belgium/27-May-2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON950045" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-05-27" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G140101-", - "T140102-", - "T140103-", - "A140104-", - "A140105-", - "T140106-", - "A140107-", - "A140108-", - "C140109-", - "A140110-", - "A140111-", - "T140112-", - "T140113-", - "A140114-", - "T140115-", - "A140116-", - "A140117-", - "C140118-", - "A140119-", - "A140120-", - "T140121-", - "T140122-", - "A140123-", - "T140124-", - "A140125-", - "A140126-", - "C140127-", - "A140128-", - "A140129-", - "T140130-", - "T140131-", - "A140132-", - "T140133-", - "A140134-", - "A140135-", - "C140136-", - "A140137-", - "A140138-", - "T140139-", - "T140140-", - "A140141-", - "T140142-", - "A140143-", - "A140144-", - "T140145-", - "T140146-", - "G140147-", - "T140148-", - "T140149-", - "A140150-", - "T140151-", - "A140152-", - "A140153-", - "T140154-", - "A140155-", - "A140156-", - "T140157-", - "T140158-", - "A140159-", - "T140160-", - "A140161-", - "A140162-", - "T140163-", - "T140164-", - "-196603A" - ], - "OPG159": [ - "V112-", - "N113-", - "N114-", - "N115-", - "Y116-", - "N117-", - "N118-", - "Y119-", - "N120-", - "N121-", - "Y122-", - "N123-", - "N124-", - "Y125-", - "N126-", - "C127-", - "Y128-", - "N129-", - "N130-", - "Y131-", - "N132-", - "C133X", - "*146X" - ] - }, - "labels": { - "aa": "OPG159: V112-, N113-, N114-, N115-, Y116-, N117-, N118-, Y119-, N120-, N121-, Y122-, N123-, N124-, Y125-, N126-, C127-, Y128-, N129-, N130-, Y131-, N132-, C133X, *146X" - } - } - }, - { - "name": "NODE_0000189", - "node_attrs": { - "div": 5, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C133161T", - "C157632T", - "T179058-", - "T179059-", - "A179060-", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-" - ] - } - }, - "children": [ - { - "name": "MPXV/ITM_pt_16/Belgium/10-Jun-2022", - "node_attrs": { - "div": 5, - "author": { - "author": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., den Bossche,D.V., Florence,E., Rezende,A.M., Vercauteren,K., Esbroeck,M.V., Bracke,S., Brosius,I., Soentjens,P.", - "value": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., den Bossche,D.V., Florence,E., Rezende,A.M., Vercauteren,K., Esbroeck,M.V., Bracke,S., Brosius,I., Soentjens,P." - }, - "strain_original": { - "value": "MPXV/ITM_pt_16/Belgium/10-Jun-2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP144212" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-10" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C146824T", - "G179020-", - "T179021-", - "C179022-", - "G179023-", - "A179024-", - "G179025-", - "T196998-" - ] - } - } - }, - { - "name": "MPXV/ITM_pt_25/Belgium/16-Jun-2022", - "node_attrs": { - "div": 5, - "author": { - "author": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., den Bossche,D.V., Florence,E., Rezende,A.M., Vercauteren,K., Esbroeck,M.V., Bracke,S., Brosius,I., Soentjens,P.", - "value": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., den Bossche,D.V., Florence,E., Rezende,A.M., Vercauteren,K., Esbroeck,M.V., Bracke,S., Brosius,I., Soentjens,P." - }, - "strain_original": { - "value": "MPXV/ITM_pt_25/Belgium/16-Jun-2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP144214" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-06-16" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-133078T", - "-179026T", - "-179027A", - "-179028T", - "-179029G", - "-179030A", - "-179031A", - "-179032T", - "-179033A", - "-179034C", - "-179035G", - "-179036G", - "-179037A", - "-179038G", - "-179039T", - "-179040A", - "-179041C", - "-179042A", - "-179043A", - "-179044A", - "-179045C", - "-179046A", - "-179047T", - "-179048A" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000190", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G85581A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "G150560-", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196603A" - ], - "OPG107": [ - "V24I" - ] - }, - "labels": { - "aa": "OPG107: V24I" - } - }, - "children": [ - { - "name": "MpxV/human/USA/OH-UW-089384/2022", - "node_attrs": { - "div": 5, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "strain_original": { - "value": "MpxV/human/USA/OH-UW-089384/2022" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP392534" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150565-", - "T150567-", - "C152973T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-" - ] - } - } - }, - { - "name": "NY-NYCPHL-000626", - "node_attrs": { - "div": 7, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000626" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468721" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-28" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T39396C", - "G66009A", - "-150560G", - "-150561A", - "-150562T", - "G150565-", - "G188294A" - ], - "OPG057": [ - "N267S" - ], - "OPG084": [ - "D430N" - ] - }, - "labels": { - "aa": "OPG057: N267S; OPG084: D430N" - } - } - }, - { - "name": "NY-NYCPHL-000466", - "node_attrs": { - "div": 4, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000466" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ504444" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-22" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150566A" - ] - } - } - } - ] - }, - { - "name": "NODE_0000191", - "node_attrs": { - "div": 7, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C8612T", - "G52232A", - "C56018T", - "G150559-", - "G150560-", - "G150565-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "G187156A" - ], - "OPG071": [ - "S736L" - ], - "OPG074": [ - "E370K" - ] - }, - "labels": { - "aa": "OPG071: S736L; OPG074: E370K" - } - }, - "children": [ - { - "name": "Slovenia-MPXV-40-2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "strain_original": { - "value": "Slovenia-MPXV-40-2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605581" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C126-" - ] - } - } - }, - { - "name": "Slovenia-MPXV-36-2022", - "node_attrs": { - "div": 10, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "strain_original": { - "value": "Slovenia-MPXV-36-2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605578" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-07-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A91-", - "C64583A", - "C115217T", - "C183631T" - ], - "OPG083": [ - "G45V" - ], - "OPG210": [ - "S759F" - ] - }, - "labels": { - "aa": "OPG083: G45V; OPG210: S759F" - } - } - }, - { - "name": "Slovenia-MPXV-44-2022", - "node_attrs": { - "div": 7, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "strain_original": { - "value": "Slovenia-MPXV-44-2022" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605585" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000192", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G152776A" - ], - "OPG180": [ - "D29N" - ] - }, - "labels": { - "aa": "OPG180: D29N" - } - }, - "children": [ - { - "name": "MPXV/human/Taiwan/109-005210/2023", - "node_attrs": { - "div": 6, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "strain_original": { - "value": "MPXV/human/Taiwan/109-005210/2023" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ581854" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Taiwan" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-02-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T64426C", - "G150559-", - "G150560-", - "G150565-", - "G158406A", - "T192403-", - "A192404-", - "G192405-", - "A192410-" - ] - } - } - }, - { - "name": "NODE_0000193", - "node_attrs": { - "div": 15, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C15969T", - "C17998T", - "G40610A", - "C43803T", - "C63879T", - "G70190A", - "G118289A", - "C147011T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "C159532T", - "G161629A", - "C189427T" - ], - "OPG005": [ - "P77S" - ], - "OPG027": [ - "E137K" - ], - "OPG031": [ - "M277I" - ], - "OPG064": [ - "G699E" - ], - "OPG083": [ - "D280N" - ], - "OPG089": [ - "E109K" - ], - "OPG185": [ - "P206S" - ], - "OPG188": [ - "E12K" - ] - }, - "labels": { - "aa": "OPG005: P77S; OPG027: E137K; OPG031: M277I; OPG064: G699E; OPG083: D280N; OPG089: E109K; OPG185: P206S; OPG188: E12K" - } - }, - "children": [ - { - "name": "MPXV/Germany/2023/RKI718", - "node_attrs": { - "div": 15, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2023/RKI718" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ451903" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-01-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Germany/2023/RKI719", - "node_attrs": { - "div": 15, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "strain_original": { - "value": "MPXV/Germany/2023/RKI719" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ451904" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-01-XX" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000194", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "C170673T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - }, - "children": [ - { - "name": "NY-NYCPHL-000621", - "node_attrs": { - "div": 8, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000621" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468717" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-20" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G12099A", - "G37328A", - "C43924T", - "G106113A", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T" - ], - "OPG023": [ - "R268*" - ], - "OPG064": [ - "D659N" - ] - }, - "labels": { - "aa": "OPG023: R268*; OPG064: D659N" - } - } - }, - { - "name": "NY-NYCPHL-000322", - "node_attrs": { - "div": 6, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-000322" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468952" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-08-08" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C5371T", - "-150550G", - "G150559-", - "G150560-", - "G150565-", - "C185767T", - "G191839A" - ], - "OPG210": [ - "S1471F" - ] - }, - "labels": { - "aa": "OPG210: S1471F" - } - } - }, - { - "name": "NODE_0000195", - "node_attrs": { - "div": 14, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C19558T", - "G32277A", - "C35688T", - "G39140A", - "G55059A", - "G75512A", - "C110402T", - "C121161T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "C179542T", - "C189174T" - ], - "NBT03_gp052": [ - "S28L" - ], - "OPG034": [ - "E150K" - ], - "OPG049": [ - "S292L" - ], - "OPG095": [ - "R237K" - ], - "OPG139": [ - "A70T" - ] - }, - "labels": { - "aa": "NBT03_gp052: S28L; OPG034: E150K; OPG049: S292L; OPG095: R237K; OPG139: A70T" - } - }, - "children": [ - { - "name": "NY-NYCPHL-001190", - "node_attrs": { - "div": 14, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-001190" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ419090" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-01-11" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NY-NYCPHL-001191", - "node_attrs": { - "div": 16, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "strain_original": { - "value": "NY-NYCPHL-001191" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ419091" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-01-11" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C134545T", - "C138212T" - ], - "OPG155": [ - "E94K" - ] - }, - "labels": { - "aa": "OPG155: E94K" - } - } - }, - { - "name": "B1221136", - "node_attrs": { - "div": 14, - "author": { - "author": "Miller,H., Bajwa,M.", - "value": "Miller,H., Bajwa,M." - }, - "strain_original": { - "value": "B1221136" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Delaware Public Health Lab, Sequencing/Bioinformatics" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR134560" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-03-13" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150550G", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000196", - "node_attrs": { - "div": 4, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G105923A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T" - ], - "OPG124": [ - "L16F" - ] - }, - "labels": { - "aa": "OPG124: L16F", - "clade": "C.1" - } - }, - "children": [ - { - "name": "MPXV/human/Japan/Tokyo/2022/TKY220176", - "node_attrs": { - "div": 4, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2022/TKY220176" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "LC753969" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Japan" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-XX" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/human/Taiwan/110-093831/2023", - "node_attrs": { - "div": 6, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "strain_original": { - "value": "MPXV/human/Taiwan/110-093831/2023" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ581853" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Taiwan" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-02-XX" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T132513C", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "C185069T" - ] - } - } - }, - { - "name": "MPXV/human/Taiwan/240031000030/2023", - "node_attrs": { - "div": 12, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "strain_original": { - "value": "MPXV/human/Taiwan/240031000030/2023" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ721952" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Taiwan" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-03-XX" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C798T", - "C13503T", - "G33539A", - "G34948A", - "G40174A", - "G156025A", - "C166940T", - "A183935G", - "A184219G", - "G193223A" - ], - "OPG025": [ - "A589T" - ], - "OPG054": [ - "A350V" - ], - "OPG057": [ - "P8S" - ], - "OPG210": [ - "I860M", - "Y955C" - ] - }, - "labels": { - "aa": "OPG025: A589T; OPG054: A350V; OPG057: P8S; OPG210: I860M, Y955C" - } - } - }, - { - "name": "MPXV/UZ_REGA_122", - "node_attrs": { - "div": 5, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "strain_original": { - "value": "MPXV/UZ_REGA_122" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035728" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-28" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "G149818A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG176": [ - "D4N" - ] - }, - "labels": { - "aa": "OPG176: D4N" - } - } - }, - { - "name": "MPXV/human/Japan/Tokyo/2022/TKY220165", - "node_attrs": { - "div": 4, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2022/TKY220165" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "LC753968" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Japan" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-09-XX" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/human/Japan/Tokyo/2022/TKY220187", - "node_attrs": { - "div": 4, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2022/TKY220187" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "LC753970" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Japan" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2022-10-XX" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000198", - "node_attrs": { - "div": 5, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C3987T" - ] - } - }, - "children": [ - { - "name": "MPXV/human/Taiwan/0310000009/2023", - "node_attrs": { - "div": 8, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "strain_original": { - "value": "MPXV/human/Taiwan/0310000009/2023" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ581855" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Taiwan" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-03-XX" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G15797A", - "C41168T", - "A137251T" - ] - } - } - }, - { - "name": "NODE_0000199", - "node_attrs": { - "div": 6, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C166940T", - "G193223A" - ] - } - }, - "children": [ - { - "name": "MPXV/human/Japan/Tokyo/2023/TKY220318", - "node_attrs": { - "div": 6, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2023/TKY220318" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "LC756923" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Japan" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-01-25" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/human/Japan/Tokyo/2023/TKY220342", - "node_attrs": { - "div": 7, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2023/TKY220342" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "LC756925" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Japan" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-02-09" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C84734T" - ] - } - } - }, - { - "name": "MPXV/human/Japan/Tokyo/2023/TKY220343", - "node_attrs": { - "div": 7, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K., Harada,S., Amano,A.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K., Harada,S., Amano,A." - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2023/TKY220343" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "LC760461" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Japan" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-02-13" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C798T", - "C68765T", - "G196412A" - ], - "OPG086": [ - "M33I" - ] - }, - "labels": { - "aa": "OPG086: M33I" - } - } - }, - { - "name": "MPXV/human/Japan/Tokyo/2023/TKY220304", - "node_attrs": { - "div": 8, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K., Harada,S., Amano,A.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K., Harada,S., Amano,A." - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2023/TKY220304" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "LC760460" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Japan" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-01-23" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G48887A", - "G75699A" - ], - "OPG096": [ - "R38Q" - ] - }, - "labels": { - "aa": "OPG096: R38Q" - } - } - }, - { - "name": "NODE_0000200", - "node_attrs": { - "div": 14, - "outbreak": { - "value": "hMPXV-1" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G143-", - "G144-", - "A145-", - "T146-", - "A147-", - "A148-", - "A149-", - "A150-", - "A151-", - "C152-", - "T153-", - "T154-", - "T155-", - "T156-", - "T157-", - "A158-", - "C159-", - "G160-", - "A161-", - "C162-", - "T163-", - "C164-", - "C165-", - "A166-", - "T167-", - "C168-", - "A169-", - "G170-", - "A171-", - "A172-", - "A173-", - "G174-", - "A175-", - "G176-", - "G177-", - "T178-", - "T179-", - "T180-", - "A181-", - "A182-", - "T183-", - "A184-", - "T185-", - "T186-", - "T187-", - "T188-", - "T189-", - "G190-", - "T191-", - "G192-", - "A193-", - "G194-", - "A195-", - "C196-", - "C197-", - "C198-", - "A199-", - "T200-", - "C201-", - "G202-", - "A203-", - "A204-", - "G205-", - "A206-", - "G207-", - "A208-", - "G209-", - "A210-", - "A211-", - "A212-", - "G213-", - "A214-", - "G215-", - "A216-", - "T217-", - "G218-", - "G219-", - "T220-", - "T221-", - "A222-", - "G223-", - "T224-", - "C225-", - "A226-", - "A227-", - "G228-", - "A229-", - "T230-", - "A231-", - "T232-", - "T233-", - "T234-", - "T235-", - "T236-", - "C237-", - "T238-", - "T239-", - "A240-", - "G241-", - "T242-", - "A243-", - "C244-", - "A245-", - "A246-", - "A247-", - "A248-", - "G249-", - "T250-", - "C251-", - "A252-", - "A253-", - "T254-", - "G255-", - "T256-", - "T257-", - "T258-", - "T259-", - "A260-", - "A261-", - "A262-", - "A263-", - "T264-", - "A265-", - "T266-", - "A267-", - "T268-", - "G269-", - "G270-", - "A271-", - "C272-", - "G273-", - "A274-", - "G275-", - "A276-", - "A277-", - "T278-", - "T279-", - "A280-", - "A281-", - "T282-", - "T283-", - "T284-", - "G285-", - "T286-", - "C287-", - "T288-", - "G289-", - "T290-", - "A291-", - "T292-", - "A293-", - "A294-", - "A295-", - "A296-", - "A297-", - "C298-", - "T299-", - "T300-", - "G301-", - "T302-", - "G303-", - "T304-", - "G305-", - "A306-", - "A307-", - "A308-", - "T309-", - "T310-", - "A311-", - "T312-", - "G313-", - "T314-", - "A315-", - "C316-", - "T317-", - "A318-", - "G319-", - "A320-", - "G321-", - "A322-", - "A323-", - "A324-", - "A325-", - "A326-", - "A327-", - "C328-", - "G329-", - "T330-", - "G331-", - "A332-", - "G333-", - "C334-", - "A335-", - "G336-", - "T337-", - "G338-", - "T339-", - "C340-", - "C341-", - "C342-", - "C343-", - "T344-", - "A345-", - "C346-", - "A347-", - "T348-", - "G349-", - "G350-", - "A351-", - "T352-", - "T353-", - "T354-", - "T355-", - "A356-", - "C357-", - "A358-", - "G359-", - "A360-", - "T361-", - "C362-", - "A363-", - "T364-", - "T365-", - "T366-", - "A367-", - "T368-", - "A369-", - "T370-", - "T371-", - "C372-", - "C373-", - "A374-", - "A375-", - "A376-", - "A377-", - "A378-", - "T379-", - "A380-", - "T381-", - "T382-", - "A383-", - "A384-", - "C385-", - "T386-", - "A387-", - "T388-", - "A389-", - "T390-", - "A391-", - "C392-", - "G393-", - "T394-", - "T395-", - "T396-", - "A397-", - "T398-", - "T399-", - "A400-", - "T401-", - "A402-", - "T403-", - "G404-", - "A405-", - "T406-", - "G407-", - "T408-", - "T409-", - "A410-", - "A411-", - "C412-", - "G413-", - "T414-", - "G415-", - "T416-", - "A417-", - "A418-", - "A419-", - "T420-", - "T421-", - "A422-", - "T423-", - "A424-", - "A425-", - "A426-", - "C427-", - "A428-", - "T429-", - "T430-", - "A431-", - "T432-", - "T433-", - "T434-", - "T435-", - "A436-", - "T437-", - "G438-", - "A439-", - "T440-", - "G441-", - "C442-", - "A443-", - "A444-", - "T445-", - "T446-", - "G447-", - "T448-", - "C449-", - "T450-", - "G451-", - "A452-", - "C453-", - "A454-", - "A455-", - "C456-", - "C457-", - "T458-", - "A459-", - "G460-", - "A461-", - "T462-", - "T463-", - "G464-", - "G465-", - "T466-", - "A467-", - "T468-", - "A469-", - "A470-", - "G471-", - "G472-", - "A473-", - "T474-", - "G475-", - "T476-", - "T477-", - "G478-", - "A479-", - "T480-", - "A481-", - "A482-", - "G483-", - "C484-", - "T485-", - "C486-", - "T487-", - "A488-", - "C489-", - "G490-", - "A491-", - "G492-", - "A493-", - "A494-", - "T495-", - "A496-", - "T497-", - "A498-", - "T499-", - "T500-", - "G501-", - "T502-", - "T503-", - "G504-", - "G505-", - "A506-", - "C507-", - "G508-", - "T509-", - "T510-", - "A511-", - "T512-", - "C513-", - "G514-", - "T515-", - "T516-", - "T517-", - "A518-", - "C519-", - "G520-", - "A521-", - "A522-", - "A523-", - "T524-", - "A525-", - "G526-", - "T527-", - "T528-", - "G529-", - "A530-", - "G531-", - "A532-", - "C533-", - "A534-", - "T535-", - "C536-", - "A539-", - "A540-", - "A541-", - "G542-", - "G544-", - "G545-", - "T546-", - "T547-", - "T548-", - "A549-", - "A550-", - "T551-", - "A552-", - "T553-", - "T554-", - "T555-", - "T557-", - "G558-", - "G560-", - "A561-", - "G562-", - "C564-", - "A566-", - "T567-", - "G572-", - "G580-", - "G582-", - "G13563A", - "C21062T", - "G101241A", - "C149963T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G152866A", - "G184562A", - "G188348A", - "C188946T", - "G191028-", - "C191029-", - "G191030-", - "A191031-", - "A191032-", - "T191033-", - "A191034-", - "A191035-", - "G191036-", - "A191037-", - "C191038-", - "A191039-", - "G191040-", - "T191041-", - "G191042-", - "C191043-", - "G191044-", - "A191045-", - "T191046-", - "T191047-", - "C191048-", - "G191049-", - "C191050-", - "A191051-", - "C191052-", - "C191053-", - "A191054-", - "T191055-", - "G191056-", - "G191057-", - "A191058-", - "G191059-", - "T191060-", - "C191061-", - "G191062-", - "G191063-", - "T191064-", - "A191065-", - "G191066-", - "A191067-", - "T191068-", - "T191069-", - "T191070-", - "C191071-", - "A191072-", - "T191073-", - "G191074-", - "G191075-", - "C191076-", - "T191077-", - "G191078-", - "T191079-", - "C191080-", - "G191081-", - "A191082-", - "T191083-", - "G191084-", - "A191085-", - "G191086-", - "C191087-", - "A191088-", - "G191089-", - "T191090-", - "T191091-", - "T191092-", - "C191093-", - "A191094-", - "C191095-", - "G191096-", - "A191097-", - "C191098-", - "G191099-", - "A191100-", - "C191101-", - "C191102-", - "T191103-", - "C191104-" - ], - "NBT03_gp175": [ - "M1-", - "E2-", - "S3-", - "V4-", - "D5-", - "F6-", - "M7-", - "A8-", - "V9-", - "D10-", - "E11-", - "Q12-", - "F13-", - "H14-", - "D15-", - "D16-", - "L17-" - ], - "OPG025": [ - "P569S" - ], - "OPG036": [ - "M1I" - ], - "OPG176": [ - "S52L" - ], - "OPG180": [ - "D59N" - ] - }, - "labels": { - "aa": "NBT03_gp175: M1-, E2-, S3-, V4-, D5-, F6-, M7-, A8-, V9-, D10-, E11-, Q12-, F13-, H14-, D15-, D16-, L17-; OPG025: P569S; OPG036: M1I; OPG176: S52L; OPG180: D59N" - } - }, - "children": [ - { - "name": "MPXV/PT0629/2023", - "node_attrs": { - "div": 14, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "MPXV/PT0629/2023" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR326993" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-06-20" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/PT0631/2023", - "node_attrs": { - "div": 17, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "strain_original": { - "value": "MPXV/PT0631/2023" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR326995" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "date": { - "value": "2023-06-22" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A537-", - "G538-", - "A543-", - "T556-", - "T559-", - "A563-", - "C565-", - "C568-", - "G569-", - "A570-", - "A571-", - "A573-", - "G574-", - "A575-", - "G576-", - "A577-", - "A578-", - "A579-", - "A581-", - "A583-", - "A584-", - "T585-", - "C34435T", - "C37738T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G151847A", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-", - "A190988-", - "G190989-", - "G190990-", - "A190991-", - "A190992-", - "A190993-", - "A190994-", - "C190995-", - "A190996-", - "T190997-", - "G190998-", - "T190999-", - "A191000-", - "C191001-", - "A191002-", - "T191003-", - "A191004-", - "A191005-", - "T191006-", - "T191007-", - "A191008-", - "T191009-", - "A191010-", - "A191011-", - "A191012-", - "A191013-", - "A191014-", - "A191015-", - "T191016-", - "G191017-", - "A191018-", - "A191019-", - "A191020-", - "A191021-", - "T191022-", - "C191023-", - "A191024-", - "A191025-", - "T191026-", - "G191027-", - "-191065A", - "-191066G", - "A196514-", - "C196515-" - ], - "NBT03_gp175": [ - "-4X", - "-5X", - "*438X" - ], - "OPG053": [ - "A86T" - ], - "OPG056": [ - "E433K" - ] - }, - "labels": { - "aa": "NBT03_gp175: -4X, -5X, *438X; OPG053: A86T; OPG056: E433K" - } - } - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } -} diff --git a/data/nextstrain/mpx/hmpxv/NC_063383.1/CHANGELOG.md b/data/nextstrain/mpx/hmpxv/NC_063383.1/CHANGELOG.md deleted file mode 100644 index 04463a94..00000000 --- a/data/nextstrain/mpx/hmpxv/NC_063383.1/CHANGELOG.md +++ /dev/null @@ -1,7 +0,0 @@ -## Unreleased - -Initial release for Nextclade v3! - -This dataset is converted from the corresponding older dataset for Nextclade v2. You can find old versions of datasets here: https://github.com/nextstrain/nextclade_data/tree/2023-08-17--15-51-24--UTC/data/datasets - -Read more about Nextclade datasets in the documentation: https://docs.nextstrain.org/projects/nextclade/en/stable/user/datasets.html diff --git a/data/nextstrain/mpx/hmpxv/NC_063383.1/README.md b/data/nextstrain/mpx/hmpxv/NC_063383.1/README.md deleted file mode 100644 index 61c56e78..00000000 --- a/data/nextstrain/mpx/hmpxv/NC_063383.1/README.md +++ /dev/null @@ -1,14 +0,0 @@ -# Nextclade dataset for "Human Monkeypox (hMPXV)" based on reference "MPXV-M5312_HM12_Rivers" (hMPXV/NC_063383.1) - - -## Dataset attributes - -| attribute | value | value friendly | -| -------------------- | -------------------- | ---------------------------------------- | -| name | hMPXV | Human Monkeypox (hMPXV) | -| reference | NC_063383.1 | MPXV-M5312_HM12_Rivers | - - -## What is Nextclade dataset - -Read more about Nextclade datasets in Nextclade documentation: https://docs.nextstrain.org/projects/nextclade/en/stable/user/datasets.html diff --git a/data/nextstrain/mpx/hmpxv/NC_063383.1/genome_annotation.gff3 b/data/nextstrain/mpx/hmpxv/NC_063383.1/genome_annotation.gff3 deleted file mode 100644 index 32348669..00000000 --- a/data/nextstrain/mpx/hmpxv/NC_063383.1/genome_annotation.gff3 +++ /dev/null @@ -1,361 +0,0 @@ -##sequence-region NC_063383.1 1 197209 -##species https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10244 -##NC_063383.1 RefSeq region 1 197209 . + . ID=NC_063383.1:1..197209;Dbxref=taxon:10244;collection-date=2018-08;country=Nigeria: Rivers State;gbkey=Src;genome=genomic;genotype=West African clade;isolate=MPXV-M5312_HM12_Rivers;mol_type=genomic DNA;nat-host=Homo sapiens -## Required edit of above line for augur translate -NC_063383.1 RefSeq source 1 197209 . + . gene_name=nuc;ID=NC_063383.1:1..197209;Dbxref=taxon:10244;collection-date=2018-08;country=Nigeria: Rivers State;gbkey=Src;genome=genomic;genotype=West African clade;isolate=MPXV-M5312_HM12_Rivers;mol_type=genomic DNA;nat-host=Homo sapiens -NC_063383.1 RefSeq gene 835 1575 . - . ID=gene-NBT03_gp001;Dbxref=GeneID:72551607;Name=OPG001;gbkey=Gene;gene_name=OPG001;gene_biotype=protein_coding;locus_tag=NBT03_gp001;old_locus_tag=MPXV-M5312_HM12_Rivers-001 -NC_063383.1 RefSeq CDS 835 1575 . - 0 ID=cds-YP_010377002.1;Parent=gene-NBT03_gp001;Dbxref=Genbank:YP_010377002.1,GeneID:72551607;Name=YP_010377002.1;Note=J1L%3B similar to Vaccinia virus strain Copenhagen C23L%3B most abundant secreted protein%3B CC-chemokine binding;gbkey=CDS;gene_name=OPG001;locus_tag=NBT03_gp001;product=MPXVgp001;protein_id=YP_010377002.1 -NC_063383.1 RefSeq gene 1702 2751 . - . ID=gene-NBT03_gp002;Dbxref=GeneID:72551418;Name=OPG002;gbkey=Gene;gene_name=OPG002;gene_biotype=protein_coding;locus_tag=NBT03_gp002;old_locus_tag=MPXV-M5312_HM12_Rivers-002 -NC_063383.1 RefSeq CDS 1702 2751 . - 0 ID=cds-YP_010377003.1;Parent=gene-NBT03_gp002;Dbxref=Genbank:YP_010377003.1,GeneID:72551418;Name=YP_010377003.1;Note=J2L;gbkey=CDS;gene_name=OPG002;locus_tag=NBT03_gp002;product=MPXVgp002;protein_id=YP_010377003.1 -NC_063383.1 RefSeq gene 2841 4607 . - . ID=gene-NBT03_gp003;Dbxref=GeneID:72551419;Name=OPG003;gbkey=Gene;gene_name=OPG003;gene_biotype=protein_coding;locus_tag=NBT03_gp003;old_locus_tag=MPXV-M5312_HM12_Rivers-003 -NC_063383.1 RefSeq CDS 2841 4607 . - 0 ID=cds-YP_010377004.1;Parent=gene-NBT03_gp003;Dbxref=Genbank:YP_010377004.1,GeneID:72551419;Name=YP_010377004.1;Note=J3L;gbkey=CDS;gene_name=OPG003;locus_tag=NBT03_gp003;product=MPXVgp003;protein_id=YP_010377004.1 -NC_063383.1 RefSeq gene 4843 6156 . - . ID=gene-NBT03_gp004;Dbxref=GeneID:72551420;Name=OPG015;gbkey=Gene;gene_name=OPG015;gene_biotype=protein_coding;locus_tag=NBT03_gp004;old_locus_tag=MPXV-M5312_HM12_Rivers-004 -NC_063383.1 RefSeq CDS 4843 6156 . - 0 ID=cds-YP_010377005.1;Parent=gene-NBT03_gp004;Dbxref=Genbank:YP_010377005.1,GeneID:72551420;Name=YP_010377005.1;Note=D1L;gbkey=CDS;gene_name=OPG015;locus_tag=NBT03_gp004;product=MPXVgp004;protein_id=YP_010377005.1 -NC_063383.1 RefSeq gene 7580 8008 . + . ID=gene-NBT03_gp005;Dbxref=GeneID:72551421;Name=OPG019;gbkey=Gene;gene_name=OPG019;gene_biotype=protein_coding;locus_tag=NBT03_gp005;old_locus_tag=MPXV-M5312_HM12_Rivers-006 -NC_063383.1 RefSeq CDS 7580 8008 . + 0 ID=cds-YP_010377006.1;Parent=gene-NBT03_gp005;Dbxref=Genbank:YP_010377006.1,GeneID:72551421;Name=YP_010377006.1;Note=D3R%3B similar to Vaccinia virus strain Copenhagen C11R%3B secreted growth factor;gbkey=CDS;gene_name=OPG019;locus_tag=NBT03_gp005;product=MPXVgp006;protein_id=YP_010377006.1 -NC_063383.1 RefSeq gene 9587 10315 . + . ID=gene-NBT03_gp006;Dbxref=GeneID:72551422;Name=OPG021;gbkey=Gene;gene_name=OPG021;gene_biotype=protein_coding;locus_tag=NBT03_gp006;old_locus_tag=MPXV-M5312_HM12_Rivers-008 -NC_063383.1 RefSeq CDS 9587 10315 . + 0 ID=cds-YP_010377007.1;Parent=gene-NBT03_gp006;Dbxref=Genbank:YP_010377007.1,GeneID:72551422;Name=YP_010377007.1;Note=D5R%3B zinc binding%3B virosome localization%3B virulence factor%3B inhibition of apoptosis induced by UV irradiation;gbkey=CDS;gene_name=OPG021;locus_tag=NBT03_gp006;product=MPXVgp008;protein_id=YP_010377007.1 -NC_063383.1 RefSeq gene 10478 10858 . - . ID=gene-NBT03_gp007;Dbxref=GeneID:72551423;Name=OPG022;gbkey=Gene;gene_name=OPG022;gene_biotype=protein_coding;locus_tag=NBT03_gp007;old_locus_tag=MPXV-M5312_HM12_Rivers-009 -NC_063383.1 RefSeq CDS 10478 10858 . - 0 ID=cds-YP_010377008.1;Parent=gene-NBT03_gp007;Dbxref=Genbank:YP_010377008.1,GeneID:72551423;Name=YP_010377008.1;Note=D6L%3B secreted IL-18 binding protein;gbkey=CDS;gene_name=OPG022;locus_tag=NBT03_gp007;product=MPXVgp009;protein_id=YP_010377008.1 -NC_063383.1 RefSeq gene 10918 12900 . - . ID=gene-NBT03_gp008;Dbxref=GeneID:72551424;Name=OPG023;gbkey=Gene;gene_name=OPG023;gene_biotype=protein_coding;locus_tag=NBT03_gp008;old_locus_tag=MPXV-M5312_HM12_Rivers-010 -NC_063383.1 RefSeq CDS 10918 12900 . - 0 ID=cds-YP_010377009.1;Parent=gene-NBT03_gp008;Dbxref=Genbank:YP_010377009.1,GeneID:72551424;Name=YP_010377009.1;Note=D7L%3B host range%3B ankyrin-like;gbkey=CDS;gene_name=OPG023;locus_tag=NBT03_gp008;product=MPXVgp010;protein_id=YP_010377009.1 -NC_063383.1 RefSeq gene 13034 13228 . - . ID=gene-NBT03_gp009;Dbxref=GeneID:72551425;Name=OPG024;gbkey=Gene;gene_name=OPG024;gene_biotype=protein_coding;locus_tag=NBT03_gp009;old_locus_tag=MPXV-M5312_HM12_Rivers-011 -NC_063383.1 RefSeq CDS 13034 13228 . - 0 ID=cds-YP_010377010.1;Parent=gene-NBT03_gp009;Dbxref=Genbank:YP_010377010.1,GeneID:72551425;Name=YP_010377010.1;Note=D8L;gbkey=CDS;gene_name=OPG024;locus_tag=NBT03_gp009;product=MPXVgp011;protein_id=YP_010377010.1 -NC_063383.1 RefSeq gene 13375 15267 . - . ID=gene-NBT03_gp010;Dbxref=GeneID:72551426;Name=OPG025;gbkey=Gene;gene_name=OPG025;gene_biotype=protein_coding;locus_tag=NBT03_gp010;old_locus_tag=MPXV-M5312_HM12_Rivers-012 -NC_063383.1 RefSeq CDS 13375 15267 . - 0 ID=cds-YP_010377011.1;Parent=gene-NBT03_gp010;Dbxref=Genbank:YP_010377011.1,GeneID:72551426;Name=YP_010377011.1;Note=D9L%3B similar to Vaccinia virus strain Copenhagen C9L%3B ankyrin-like;gbkey=CDS;gene_name=OPG025;locus_tag=NBT03_gp010;product=MPXVgp012;protein_id=YP_010377011.1 -NC_063383.1 RefSeq gene 15925 16377 . - . ID=gene-NBT03_gp011;Dbxref=GeneID:72551427;Name=OPG027;gbkey=Gene;gene_name=OPG027;gene_biotype=protein_coding;locus_tag=NBT03_gp011;old_locus_tag=MPXV-M5312_HM12_Rivers-013 -NC_063383.1 RefSeq CDS 15925 16377 . - 0 ID=cds-YP_010377012.1;Parent=gene-NBT03_gp011;Dbxref=Genbank:YP_010377012.1,GeneID:72551427;Name=YP_010377012.1;Note=D10L%3B similar to Vaccinia virus strain Copenhagen C7L%3B host range;gbkey=CDS;gene_name=OPG027;locus_tag=NBT03_gp011;product=MPXVgp013;protein_id=YP_010377012.1 -NC_063383.1 RefSeq gene 16602 17069 . - . ID=gene-NBT03_gp012;Dbxref=GeneID:72551428;Name=OPG029;gbkey=Gene;gene_name=OPG029;gene_biotype=protein_coding;locus_tag=NBT03_gp012;old_locus_tag=MPXV-M5312_HM12_Rivers-014 -NC_063383.1 RefSeq CDS 16602 17069 . - 0 ID=cds-YP_010377013.1;Parent=gene-NBT03_gp012;Dbxref=Genbank:YP_010377013.1,GeneID:72551428;Name=YP_010377013.1;Note=D11L%3B similar to Vaccinia virus strain Copenhagen C6L;gbkey=CDS;gene_name=OPG029;locus_tag=NBT03_gp012;product=MPXVgp014;protein_id=YP_010377013.1 -NC_063383.1 RefSeq gene 17213 17833 . - . ID=gene-NBT03_gp013;Dbxref=GeneID:72551429;Name=OPG030;gbkey=Gene;gene_name=OPG030;gene_biotype=protein_coding;locus_tag=NBT03_gp013;old_locus_tag=MPXV-M5312_HM12_Rivers-015 -NC_063383.1 RefSeq CDS 17213 17833 . - 0 ID=cds-YP_010377014.1;Parent=gene-NBT03_gp013;Dbxref=Genbank:YP_010377014.1,GeneID:72551429;Name=YP_010377014.1;Note=D12L%3B similar to Vaccinia virus strain Copenhagen C5L%3B BTB domain of kelch-like protein;gbkey=CDS;gene_name=OPG030;locus_tag=NBT03_gp013;product=MPXVgp015;protein_id=YP_010377014.1 -NC_063383.1 RefSeq gene 17878 18828 . - . ID=gene-NBT03_gp014;Dbxref=GeneID:72551430;Name=OPG031;gbkey=Gene;gene_name=OPG031;gene_biotype=protein_coding;locus_tag=NBT03_gp014;old_locus_tag=MPXV-M5312_HM12_Rivers-016 -NC_063383.1 RefSeq CDS 17878 18828 . - 0 ID=cds-YP_010377015.1;Parent=gene-NBT03_gp014;Dbxref=Genbank:YP_010377015.1,GeneID:72551430;Name=YP_010377015.1;Note=D13L%3B similar to Vaccinia virus strain Copenhagen C4L;gbkey=CDS;gene_name=OPG031;locus_tag=NBT03_gp014;product=MPXVgp016;protein_id=YP_010377015.1 -NC_063383.1 RefSeq gene 19361 20005 . - . ID=gene-NBT03_gp015;Dbxref=GeneID:72551431;Name=OPG034;gbkey=Gene;gene_name=OPG034;gene_biotype=protein_coding;locus_tag=NBT03_gp015;old_locus_tag=MPXV-M5312_HM12_Rivers-018 -NC_063383.1 RefSeq CDS 19361 20005 . - 0 ID=cds-YP_010377017.1;Parent=gene-NBT03_gp015;Dbxref=Genbank:YP_010377017.1,GeneID:72551431;Name=YP_010377017.1;Note=D19L%3B similar to Vaccinia virus strain Copenhagen C1L;gbkey=CDS;gene_name=OPG034;locus_tag=NBT03_gp015;product=MPXVgp022;protein_id=YP_010377017.1 -NC_063383.1 RefSeq gene 20051 20404 . - . ID=gene-NBT03_gp016;Dbxref=GeneID:72551432;Name=OPG035;gbkey=Gene;gene_name=OPG035;gene_biotype=protein_coding;locus_tag=NBT03_gp016;old_locus_tag=MPXV-M5312_HM12_Rivers-019 -NC_063383.1 RefSeq CDS 20051 20404 . - 0 ID=cds-YP_010377018.1;Parent=gene-NBT03_gp016;Dbxref=Genbank:YP_010377018.1,GeneID:72551432;Name=YP_010377018.1;Note=P1L%3B similar to Vaccinia virus strain Copenhagen N1L%3B secreted virulence factor;gbkey=CDS;gene_name=OPG035;locus_tag=NBT03_gp016;product=MPXVgp023;protein_id=YP_010377018.1 -NC_063383.1 RefSeq gene 20531 21064 . - . ID=gene-NBT03_gp017;Dbxref=GeneID:72551433;Name=OPG036;gbkey=Gene;gene_name=OPG036;gene_biotype=protein_coding;locus_tag=NBT03_gp017;old_locus_tag=MPXV-M5312_HM12_Rivers-020 -NC_063383.1 RefSeq CDS 20531 21064 . - 0 ID=cds-YP_010377019.1;Parent=gene-NBT03_gp017;Dbxref=Genbank:YP_010377019.1,GeneID:72551433;Name=YP_010377019.1;Note=P2L%3B similar to Vaccinia virus strain Copenhagen N2L;gbkey=CDS;gene_name=OPG036;locus_tag=NBT03_gp017;product=MPXVgp024;protein_id=YP_010377019.1 -NC_063383.1 RefSeq gene 21105 22433 . - . ID=gene-NBT03_gp018;Dbxref=GeneID:72551434;Name=OPG037;gbkey=Gene;gene_name=OPG037;gene_biotype=protein_coding;locus_tag=NBT03_gp018;old_locus_tag=MPXV-M5312_HM12_Rivers-021 -NC_063383.1 RefSeq CDS 21105 22433 . - 0 ID=cds-YP_010377020.1;Parent=gene-NBT03_gp018;Dbxref=Genbank:YP_010377020.1,GeneID:72551434;Name=YP_010377020.1;Note=O1L%3B similar to Vaccinia virus strain Copenhagen M1L%3B ankyrin-like;gbkey=CDS;gene_name=OPG037;locus_tag=NBT03_gp018;product=MPXVgp025;protein_id=YP_010377020.1 -NC_063383.1 RefSeq gene 22497 23159 . - . ID=gene-NBT03_gp019;Dbxref=GeneID:72551435;Name=OPG038;gbkey=Gene;gene_name=OPG038;gene_biotype=protein_coding;locus_tag=NBT03_gp019;old_locus_tag=MPXV-M5312_HM12_Rivers-022 -NC_063383.1 RefSeq CDS 22497 23159 . - 0 ID=cds-YP_010377021.1;Parent=gene-NBT03_gp019;Dbxref=Genbank:YP_010377021.1,GeneID:72551435;Name=YP_010377021.1;Note=O2L%3B similar to Vaccinia virus strain Copenhagen M2L;gbkey=CDS;gene_name=OPG038;locus_tag=NBT03_gp019;product=MPXVgp026;protein_id=YP_010377021.1 -NC_063383.1 RefSeq gene 23264 24118 . - . ID=gene-NBT03_gp020;Dbxref=GeneID:72551436;Name=OPG039;gbkey=Gene;gene_name=OPG039;gene_biotype=protein_coding;locus_tag=NBT03_gp020;old_locus_tag=MPXV-M5312_HM12_Rivers-023 -NC_063383.1 RefSeq CDS 23264 24118 . - 0 ID=cds-YP_010377022.1;Parent=gene-NBT03_gp020;Dbxref=Genbank:YP_010377022.1,GeneID:72551436;Name=YP_010377022.1;Note=C1L%3B similar to Vaccinia virus strain Copenhagen K1L%3B host range%3B ankyrin-like;gbkey=CDS;gene_name=OPG039;locus_tag=NBT03_gp020;product=MPXVgp027;protein_id=YP_010377022.1 -NC_063383.1 RefSeq gene 24351 25478 . - . ID=gene-NBT03_gp021;Dbxref=GeneID:72551437;Name=OPG040;gbkey=Gene;gene_name=OPG040;gene_biotype=protein_coding;locus_tag=NBT03_gp021;old_locus_tag=MPXV-M5312_HM12_Rivers-024 -NC_063383.1 RefSeq CDS 24351 25478 . - 0 ID=cds-YP_010377023.1;Parent=gene-NBT03_gp021;Dbxref=Genbank:YP_010377023.1,GeneID:72551437;Name=YP_010377023.1;Note=SPI-3%3B C2L%3B similar to Vaccinia virus strain Copenhagen K2L%3B serine protease inhibitor-like%2C SPI-3%3B inhibition of the ability of infected cells to fuse;gbkey=CDS;gene_name=OPG040;locus_tag=NBT03_gp021;product=MPXVgp028;protein_id=YP_010377023.1 -NC_063383.1 RefSeq gene 25823 27097 . - . ID=gene-NBT03_gp022;Dbxref=GeneID:72551438;Name=OPG042;gbkey=Gene;gene_name=OPG042;gene_biotype=protein_coding;locus_tag=NBT03_gp022;old_locus_tag=MPXV-M5312_HM12_Rivers-026 -NC_063383.1 RefSeq CDS 25823 27097 . - 0 ID=cds-YP_010377025.1;Parent=gene-NBT03_gp022;Dbxref=Genbank:YP_010377025.1,GeneID:72551438;Name=YP_010377025.1;Note=C4L%3B similar to Vaccinia virus strain Copenhagen K4L%3B phospholipase D-like;gbkey=CDS;gene_name=OPG042;locus_tag=NBT03_gp022;product=MPXVgp030;protein_id=YP_010377025.1 -NC_063383.1 RefSeq gene 27125 27955 . - . ID=gene-NBT03_gp023;Dbxref=GeneID:72551439;Name=OPG043;gbkey=Gene;gene_name=OPG043;gene_biotype=protein_coding;locus_tag=NBT03_gp023;old_locus_tag=MPXV-M5312_HM12_Rivers-027 -NC_063383.1 RefSeq CDS 27125 27955 . - 0 ID=cds-YP_010377026.1;Parent=gene-NBT03_gp023;Dbxref=Genbank:YP_010377026.1,GeneID:72551439;Name=YP_010377026.1;Note=C5L%3B lysophospholipase-like;gbkey=CDS;gene_name=OPG043;locus_tag=NBT03_gp023;product=MPXVgp031;protein_id=YP_010377026.1 -NC_063383.1 RefSeq gene 28091 28540 . + . ID=gene-NBT03_gp024;Dbxref=GeneID:72551440;Name=OPG044;gbkey=Gene;gene_name=OPG044;gene_biotype=protein_coding;locus_tag=NBT03_gp024;old_locus_tag=MPXV-M5312_HM12_Rivers-028 -NC_063383.1 RefSeq CDS 28091 28540 . + 0 ID=cds-YP_010377027.1;Parent=gene-NBT03_gp024;Dbxref=Genbank:YP_010377027.1,GeneID:72551440;Name=YP_010377027.1;Note=C6R%3B similar to Vaccinia virus strain Copenhagen K7R%3B VAC B15R-like;gbkey=CDS;gene_name=OPG044;locus_tag=NBT03_gp024;product=MPXVgp032;protein_id=YP_010377027.1 -NC_063383.1 RefSeq gene 28603 29262 . - . ID=gene-NBT03_gp025;Dbxref=GeneID:72551441;Name=OPG045;gbkey=Gene;gene_name=OPG045;gene_biotype=protein_coding;locus_tag=NBT03_gp025;old_locus_tag=MPXV-M5312_HM12_Rivers-029 -NC_063383.1 RefSeq CDS 28603 29262 . - 0 ID=cds-YP_010377028.1;Parent=gene-NBT03_gp025;Dbxref=Genbank:YP_010377028.1,GeneID:72551441;Name=YP_010377028.1;Note=C7L%3B similar to Vaccinia virus strain Copenhagen F1L;gbkey=CDS;gene_name=OPG045;locus_tag=NBT03_gp025;product=MPXVgp033;protein_id=YP_010377028.1 -NC_063383.1 RefSeq gene 29274 29729 . - . ID=gene-NBT03_gp026;Dbxref=GeneID:72551442;Name=OPG046;gbkey=Gene;gene_name=OPG046;gene_biotype=protein_coding;locus_tag=NBT03_gp026;old_locus_tag=MPXV-M5312_HM12_Rivers-030 -NC_063383.1 RefSeq CDS 29274 29729 . - 0 ID=cds-YP_010377029.1;Parent=gene-NBT03_gp026;Dbxref=Genbank:YP_010377029.1,GeneID:72551442;Name=YP_010377029.1;Note=C8L%3B similar to Vaccinia virus strain Copenhagen F2L%3B deoxyuridine triphosphatase;gbkey=CDS;gene_name=OPG046;locus_tag=NBT03_gp026;product=MPXVgp034;protein_id=YP_010377029.1 -NC_063383.1 RefSeq gene 29746 31194 . - . ID=gene-NBT03_gp027;Dbxref=GeneID:72551443;Name=OPG047;gbkey=Gene;gene_name=OPG047;gene_biotype=protein_coding;locus_tag=NBT03_gp027;old_locus_tag=MPXV-M5312_HM12_Rivers-031 -NC_063383.1 RefSeq CDS 29746 31194 . - 0 ID=cds-YP_010377030.1;Parent=gene-NBT03_gp027;Dbxref=Genbank:YP_010377030.1,GeneID:72551443;Name=YP_010377030.1;Note=C9L%3B similar to Vaccinia virus strain Copenhagen F3L%3B kelch-like;gbkey=CDS;gene_name=OPG047;locus_tag=NBT03_gp027;product=MPXVgp035;protein_id=YP_010377030.1 -NC_063383.1 RefSeq gene 31205 32164 . - . ID=gene-NBT03_gp028;Dbxref=GeneID:72551444;Name=OPG048;gbkey=Gene;gene_name=OPG048;gene_biotype=protein_coding;locus_tag=NBT03_gp028;old_locus_tag=MPXV-M5312_HM12_Rivers-032 -NC_063383.1 RefSeq CDS 31205 32164 . - 0 ID=cds-YP_010377031.1;Parent=gene-NBT03_gp028;Dbxref=Genbank:YP_010377031.1,GeneID:72551444;Name=YP_010377031.1;Note=C10L%3B similar to Vaccinia virus strain Copenhagen F4L%3B ribonucleotide reductase%2C small subunit%2C R2;gbkey=CDS;gene_name=OPG048;locus_tag=NBT03_gp028;product=MPXVgp036;protein_id=YP_010377031.1 -NC_063383.1 RefSeq gene 32195 33151 . - . ID=gene-NBT03_gp029;Dbxref=GeneID:72551445;Name=OPG049;gbkey=Gene;gene_name=OPG049;gene_biotype=protein_coding;locus_tag=NBT03_gp029;old_locus_tag=MPXV-M5312_HM12_Rivers-033 -NC_063383.1 RefSeq CDS 32195 33151 . - 0 ID=cds-YP_010377032.1;Parent=gene-NBT03_gp029;Dbxref=Genbank:YP_010377032.1,GeneID:72551445;Name=YP_010377032.1;Note=C11L%3B similar to Vaccinia virus strain Copenhagen F5L;gbkey=CDS;gene_name=OPG049;locus_tag=NBT03_gp029;product=MPXVgp037;protein_id=YP_010377032.1 -NC_063383.1 RefSeq gene 33181 33408 . - . ID=gene-NBT03_gp030;Dbxref=GeneID:72551446;Name=OPG050;gbkey=Gene;gene_name=OPG050;gene_biotype=protein_coding;locus_tag=NBT03_gp030;old_locus_tag=MPXV-M5312_HM12_Rivers-034 -NC_063383.1 RefSeq CDS 33181 33408 . - 0 ID=cds-YP_010377033.1;Parent=gene-NBT03_gp030;Dbxref=Genbank:YP_010377033.1,GeneID:72551446;Name=YP_010377033.1;Note=C12L%3B similar to Vaccinia virus strain Copenhagen F6L;gbkey=CDS;gene_name=OPG050;locus_tag=NBT03_gp030;product=MPXVgp038;protein_id=YP_010377033.1 -NC_063383.1 RefSeq gene 33425 33649 . - . ID=gene-NBT03_gp031;Dbxref=GeneID:72551447;Name=OPG051;gbkey=Gene;gene_name=OPG051;gene_biotype=protein_coding;locus_tag=NBT03_gp031;old_locus_tag=MPXV-M5312_HM12_Rivers-035 -NC_063383.1 RefSeq CDS 33425 33649 . - 0 ID=cds-YP_010377034.1;Parent=gene-NBT03_gp031;Dbxref=Genbank:YP_010377034.1,GeneID:72551447;Name=YP_010377034.1;Note=C13L%3B similar to Vaccinia virus strain Copenhagen F7L;gbkey=CDS;gene_name=OPG051;locus_tag=NBT03_gp031;product=MPXVgp039;protein_id=YP_010377034.1 -NC_063383.1 RefSeq gene 33801 33995 . - . ID=gene-NBT03_gp032;Dbxref=GeneID:72551448;Name=OPG052;gbkey=Gene;gene_name=OPG052;gene_biotype=protein_coding;locus_tag=NBT03_gp032;old_locus_tag=MPXV-M5312_HM12_Rivers-036 -NC_063383.1 RefSeq CDS 33801 33995 . - 0 ID=cds-YP_010377035.1;Parent=gene-NBT03_gp032;Dbxref=Genbank:YP_010377035.1,GeneID:72551448;Name=YP_010377035.1;Note=C14L%3B similar to Vaccinia virus strain Copenhagen F8L;gbkey=CDS;gene_name=OPG052;locus_tag=NBT03_gp032;product=MPXVgp040;protein_id=YP_010377035.1 -NC_063383.1 RefSeq gene 34052 34690 . - . ID=gene-NBT03_gp033;Dbxref=GeneID:72551449;Name=OPG053;gbkey=Gene;gene_name=OPG053;gene_biotype=protein_coding;locus_tag=NBT03_gp033;old_locus_tag=MPXV-M5312_HM12_Rivers-037 -NC_063383.1 RefSeq CDS 34052 34690 . - 0 ID=cds-YP_010377036.1;Parent=gene-NBT03_gp033;Dbxref=Genbank:YP_010377036.1,GeneID:72551449;Name=YP_010377036.1;Note=C15L%3B similar to Vaccinia virus strain Copenhagen F9L;gbkey=CDS;gene_name=OPG053;locus_tag=NBT03_gp033;product=MPXVgp041;protein_id=YP_010377036.1 -NC_063383.1 RefSeq gene 34677 35996 . - . ID=gene-NBT03_gp034;Dbxref=GeneID:72551450;Name=OPG054;gbkey=Gene;gene_name=OPG054;gene_biotype=protein_coding;locus_tag=NBT03_gp034;old_locus_tag=MPXV-M5312_HM12_Rivers-038 -NC_063383.1 RefSeq CDS 34677 35996 . - 0 ID=cds-YP_010377037.1;Parent=gene-NBT03_gp034;Dbxref=Genbank:YP_010377037.1,GeneID:72551450;Name=YP_010377037.1;Note=C16L%3B similar to Vaccinia virus strain Copenhagen F10L%3B serine;gbkey=CDS;gene_name=OPG054;locus_tag=NBT03_gp034;product=MPXVgp042;protein_id=YP_010377037.1 -NC_063383.1 RefSeq gene 36019 37083 . - . ID=gene-NBT03_gp035;Dbxref=GeneID:72551451;Name=OPG055;gbkey=Gene;gene_name=OPG055;gene_biotype=protein_coding;locus_tag=NBT03_gp035;old_locus_tag=MPXV-M5312_HM12_Rivers-039 -NC_063383.1 RefSeq CDS 36019 37083 . - 0 ID=cds-YP_010377038.1;Parent=gene-NBT03_gp035;Dbxref=Genbank:YP_010377038.1,GeneID:72551451;Name=YP_010377038.1;Note=C17L%3B similar to Vaccinia virus strain Copenhagen F11L;gbkey=CDS;gene_name=OPG055;locus_tag=NBT03_gp035;product=MPXVgp043;protein_id=YP_010377038.1 -NC_063383.1 RefSeq gene 37127 39034 . - . ID=gene-NBT03_gp036;Dbxref=GeneID:72551452;Name=OPG056;gbkey=Gene;gene_name=OPG056;gene_biotype=protein_coding;locus_tag=NBT03_gp036;old_locus_tag=MPXV-M5312_HM12_Rivers-040 -NC_063383.1 RefSeq CDS 37127 39034 . - 0 ID=cds-YP_010377039.1;Parent=gene-NBT03_gp036;Dbxref=Genbank:YP_010377039.1,GeneID:72551452;Name=YP_010377039.1;Note=C18L%3B similar to Vaccinia virus strain Copenhagen F12L%3B actin tail formation;gbkey=CDS;gene_name=OPG056;locus_tag=NBT03_gp036;product=MPXVgp044;protein_id=YP_010377039.1 -NC_063383.1 RefSeq gene 39077 40195 . - . ID=gene-NBT03_gp037;Dbxref=GeneID:72551453;Name=OPG057;gbkey=Gene;gene_name=OPG057;gene_biotype=protein_coding;locus_tag=NBT03_gp037;old_locus_tag=MPXV-M5312_HM12_Rivers-041 -NC_063383.1 RefSeq CDS 39077 40195 . - 0 ID=cds-YP_010377040.1;Parent=gene-NBT03_gp037;Dbxref=Genbank:YP_010377040.1,GeneID:72551453;Name=YP_010377040.1;Note=C19L%3B similar to Vaccinia virus strain Copenhagen F13L%3B major envelope antigen of EEV%3B wrapping of IMV to form IEV%3B phospholipase D-like;gbkey=CDS;gene_name=OPG057;locus_tag=NBT03_gp037;product=MPXVgp045;protein_id=YP_010377040.1 -NC_063383.1 RefSeq gene 40213 40434 . - . ID=gene-NBT03_gp038;Dbxref=GeneID:72551454;Name=OPG058;gbkey=Gene;gene_name=OPG058;gene_biotype=protein_coding;locus_tag=NBT03_gp038;old_locus_tag=MPXV-M5312_HM12_Rivers-042 -NC_063383.1 RefSeq CDS 40213 40434 . - 0 ID=cds-YP_010377041.1;Parent=gene-NBT03_gp038;Dbxref=Genbank:YP_010377041.1,GeneID:72551454;Name=YP_010377041.1;Note=C20L%3B similar to Vaccinia virus strain Copenhagen F14L;gbkey=CDS;gene_name=OPG058;locus_tag=NBT03_gp038;product=MPXVgp046;protein_id=YP_010377041.1 -NC_063383.1 RefSeq gene 40484 40633 . - . ID=gene-NBT03_gp039;Dbxref=GeneID:72551455;Name=OPG059;gbkey=Gene;gene_name=OPG059;gene_biotype=protein_coding;locus_tag=NBT03_gp039;old_locus_tag=MPXV-M5312_HM12_Rivers-043 -NC_063383.1 RefSeq CDS 40484 40633 . - 0 ID=cds-YP_010377042.1;Parent=gene-NBT03_gp039;Dbxref=Genbank:YP_010377042.1,GeneID:72551455;Name=YP_010377042.1;gbkey=CDS;gene_name=OPG059;locus_tag=NBT03_gp039;product=C20.5L;protein_id=YP_010377042.1 -NC_063383.1 RefSeq gene 40706 41182 . - . ID=gene-NBT03_gp040;Dbxref=GeneID:72551456;Name=OPG060;gbkey=Gene;gene_name=OPG060;gene_biotype=protein_coding;locus_tag=NBT03_gp040;old_locus_tag=MPXV-M5312_HM12_Rivers-044 -NC_063383.1 RefSeq CDS 40706 41182 . - 0 ID=cds-YP_010377043.1;Parent=gene-NBT03_gp040;Dbxref=Genbank:YP_010377043.1,GeneID:72551456;Name=YP_010377043.1;Note=C21L%3B similar to Vaccinia virus strain Copenhagen F15L;gbkey=CDS;gene_name=OPG060;locus_tag=NBT03_gp040;product=MPXVgp047;protein_id=YP_010377043.1 -NC_063383.1 RefSeq gene 41189 41884 . - . ID=gene-NBT03_gp041;Dbxref=GeneID:72551457;Name=OPG061;gbkey=Gene;gene_name=OPG061;gene_biotype=protein_coding;locus_tag=NBT03_gp041;old_locus_tag=MPXV-M5312_HM12_Rivers-045 -NC_063383.1 RefSeq CDS 41189 41884 . - 0 ID=cds-YP_010377044.1;Parent=gene-NBT03_gp041;Dbxref=Genbank:YP_010377044.1,GeneID:72551457;Name=YP_010377044.1;Note=C22L%3B similar to Vaccinia virus strain Copenhagen F16L;gbkey=CDS;gene_name=OPG061;locus_tag=NBT03_gp041;product=MPXVgp048;protein_id=YP_010377044.1 -NC_063383.1 RefSeq gene 41947 42252 . + . ID=gene-NBT03_gp042;Dbxref=GeneID:72551458;Name=OPG062;gbkey=Gene;gene_name=OPG062;gene_biotype=protein_coding;locus_tag=NBT03_gp042;old_locus_tag=MPXV-M5312_HM12_Rivers-046 -NC_063383.1 RefSeq CDS 41947 42252 . + 0 ID=cds-YP_010377045.1;Parent=gene-NBT03_gp042;Dbxref=Genbank:YP_010377045.1,GeneID:72551458;Name=YP_010377045.1;Note=C23R%3B similar to Vaccinia virus strain Copenhagen F17R%3B virion core DNA-binding phosphoprotein;gbkey=CDS;gene_name=OPG062;locus_tag=NBT03_gp042;product=MPXVgp049;protein_id=YP_010377045.1 -NC_063383.1 RefSeq gene 42249 43688 . - . ID=gene-NBT03_gp043;Dbxref=GeneID:72551459;Name=OPG063;gbkey=Gene;gene_name=OPG063;gene_biotype=protein_coding;locus_tag=NBT03_gp043;old_locus_tag=MPXV-M5312_HM12_Rivers-047 -NC_063383.1 RefSeq CDS 42249 43688 . - 0 ID=cds-YP_010377046.1;Parent=gene-NBT03_gp043;Dbxref=Genbank:YP_010377046.1,GeneID:72551459;Name=YP_010377046.1;Note=F1L%3B similar to Vaccinia virus strain Copenhagen E1L%3B poly-A polymerase%2C catalytic subunit;gbkey=CDS;gene_name=OPG063;locus_tag=NBT03_gp043;product=MPXVgp050;protein_id=YP_010377046.1 -NC_063383.1 RefSeq gene 43685 45898 . - . ID=gene-NBT03_gp044;Dbxref=GeneID:72551460;Name=OPG064;gbkey=Gene;gene_name=OPG064;gene_biotype=protein_coding;locus_tag=NBT03_gp044;old_locus_tag=MPXV-M5312_HM12_Rivers-048 -NC_063383.1 RefSeq CDS 43685 45898 . - 0 ID=cds-YP_010377047.1;Parent=gene-NBT03_gp044;Dbxref=Genbank:YP_010377047.1,GeneID:72551460;Name=YP_010377047.1;Note=F2L%3B similar to Vaccinia virus strain Copenhagen E2L;gbkey=CDS;gene_name=OPG064;locus_tag=NBT03_gp044;product=MPXVgp051;protein_id=YP_010377047.1 -NC_063383.1 RefSeq gene 46022 46483 . - . ID=gene-NBT03_gp045;Dbxref=GeneID:72551461;Name=OPG065;gbkey=Gene;gene_name=OPG065;gene_biotype=protein_coding;locus_tag=NBT03_gp045;old_locus_tag=MPXV-M5312_HM12_Rivers-049 -NC_063383.1 RefSeq CDS 46022 46483 . - 0 ID=cds-YP_010377048.1;Parent=gene-NBT03_gp045;Dbxref=Genbank:YP_010377048.1,GeneID:72551461;Name=YP_010377048.1;Note=F3L%3B similar to Vaccinia virus strain Copenhagen E3L%3B interferon resistance factor%3B two forms (25 kDa and 19 kDa) of the dsRNA-binding protein%3B inhibition of dsRNA-dependent protein kinase and 2-5A-synthet;gbkey=CDS;gene_name=OPG065;locus_tag=NBT03_gp045;product=MPXVgp052;protein_id=YP_010377048.1 -NC_063383.1 RefSeq gene 46649 47428 . - . ID=gene-NBT03_gp046;Dbxref=GeneID:72551462;Name=OPG066;gbkey=Gene;gene_name=OPG066;gene_biotype=protein_coding;locus_tag=NBT03_gp046;old_locus_tag=MPXV-M5312_HM12_Rivers-050 -NC_063383.1 RefSeq CDS 46649 47428 . - 0 ID=cds-YP_010377049.1;Parent=gene-NBT03_gp046;Dbxref=Genbank:YP_010377049.1,GeneID:72551462;Name=YP_010377049.1;Note=F4L%3B similar to Vaccinia virus strain Copenhagen E4L%3B RNA polymerase 30 kDa subunit%3B simultaneously intermediate stage promoter-specific transcription factor%2C VITF-1;gbkey=CDS;gene_name=OPG066;locus_tag=NBT03_gp046;product=MPXVgp053;protein_id=YP_010377049.1 -NC_063383.1 RefSeq gene 48201 49904 . + . ID=gene-NBT03_gp047;Dbxref=GeneID:72551463;Name=OPG068;gbkey=Gene;gene_name=OPG068;gene_biotype=protein_coding;locus_tag=NBT03_gp047;old_locus_tag=MPXV-M5312_HM12_Rivers-052 -NC_063383.1 RefSeq CDS 48201 49904 . + 0 ID=cds-YP_010377051.1;Parent=gene-NBT03_gp047;Dbxref=Genbank:YP_010377051.1,GeneID:72551463;Name=YP_010377051.1;Note=F5R%3B similar to Vaccinia virus strain Copenhagen E6R;gbkey=CDS;gene_name=OPG068;locus_tag=NBT03_gp047;product=MPXVgp054;protein_id=YP_010377051.1 -NC_063383.1 RefSeq gene 49986 50486 . + . ID=gene-NBT03_gp048;Dbxref=GeneID:72551464;Name=OPG069;gbkey=Gene;gene_name=OPG069;gene_biotype=protein_coding;locus_tag=NBT03_gp048;old_locus_tag=MPXV-M5312_HM12_Rivers-053 -NC_063383.1 RefSeq CDS 49986 50486 . + 0 ID=cds-YP_010377052.1;Parent=gene-NBT03_gp048;Dbxref=Genbank:YP_010377052.1,GeneID:72551464;Name=YP_010377052.1;Note=F6R%3B similar to Vaccinia virus strain Copenhagen E7R%3B soluble myristylated protein;gbkey=CDS;gene_name=OPG069;locus_tag=NBT03_gp048;product=MPXVgp055;protein_id=YP_010377052.1 -NC_063383.1 RefSeq gene 50590 51411 . + . ID=gene-NBT03_gp049;Dbxref=GeneID:72551465;Name=OPG070;gbkey=Gene;gene_name=OPG070;gene_biotype=protein_coding;locus_tag=NBT03_gp049;old_locus_tag=MPXV-M5312_HM12_Rivers-054 -NC_063383.1 RefSeq CDS 50590 51411 . + 0 ID=cds-YP_010377053.1;Parent=gene-NBT03_gp049;Dbxref=Genbank:YP_010377053.1,GeneID:72551465;Name=YP_010377053.1;Note=F7R%3B similar to Vaccinia virus strain Copenhagen E8R;gbkey=CDS;gene_name=OPG070;locus_tag=NBT03_gp049;product=MPXVgp056;protein_id=YP_010377053.1 -NC_063383.1 RefSeq gene 51418 54438 . - . ID=gene-NBT03_gp050;Dbxref=GeneID:72551466;Name=OPG071;gbkey=Gene;gene_name=OPG071;gene_biotype=protein_coding;locus_tag=NBT03_gp050;old_locus_tag=MPXV-M5312_HM12_Rivers-055 -NC_063383.1 RefSeq CDS 51418 54438 . - 0 ID=cds-YP_010377054.1;Parent=gene-NBT03_gp050;Dbxref=Genbank:YP_010377054.1,GeneID:72551466;Name=YP_010377054.1;Note=F8L%3B similar to Vaccinia virus strain Copenhagen E9L%3B DNA polymerase%2C catalytic subunit;gbkey=CDS;gene_name=OPG071;locus_tag=NBT03_gp050;product=MPXVgp057;protein_id=YP_010377054.1 -NC_063383.1 RefSeq gene 54470 54757 . + . ID=gene-NBT03_gp051;Dbxref=GeneID:72551467;Name=OPG072;gbkey=Gene;gene_name=OPG072;gene_biotype=protein_coding;locus_tag=NBT03_gp051;old_locus_tag=MPXV-M5312_HM12_Rivers-056 -NC_063383.1 RefSeq CDS 54470 54757 . + 0 ID=cds-YP_010377055.1;Parent=gene-NBT03_gp051;Dbxref=Genbank:YP_010377055.1,GeneID:72551467;Name=YP_010377055.1;Note=F9R%3B similar to Vaccinia virus strain Copenhagen E10R%3B protein disulfide bond-forming enzyme;gbkey=CDS;gene_name=OPG072;locus_tag=NBT03_gp051;product=MPXVgp058;protein_id=YP_010377055.1 -NC_063383.1 RefSeq gene 54752 55141 . - . ID=gene-NBT03_gp052;Dbxref=GeneID:72551468;Name=NBT03_gp052;gbkey=Gene;gene_biotype=protein_coding;locus_tag=NBT03_gp052;old_locus_tag=MPXV-M5312_HM12_Rivers-057 -NC_063383.1 RefSeq CDS 54752 55141 . - 0 ID=cds-YP_010377056.1;Parent=gene-NBT03_gp052;Dbxref=Genbank:YP_010377056.1,GeneID:72551468;Name=YP_010377056.1;Note=F10L%3B similar to Vaccinia virus strain Copenhagen E11L%3B virion core protein;gbkey=CDS;locus_tag=NBT03_gp052;product=MPXVgp059;protein_id=YP_010377056.1 -NC_063383.1 RefSeq gene 55128 57125 . - . ID=gene-NBT03_gp053;Dbxref=GeneID:72551469;Name=OPG074;gbkey=Gene;gene_name=OPG074;gene_biotype=protein_coding;locus_tag=NBT03_gp053;old_locus_tag=MPXV-M5312_HM12_Rivers-058 -NC_063383.1 RefSeq CDS 55128 57125 . - 0 ID=cds-YP_010377057.1;Parent=gene-NBT03_gp053;Dbxref=Genbank:YP_010377057.1,GeneID:72551469;Name=YP_010377057.1;Note=Q1L%3B similar to Vaccinia virus strain Copenhagen O1L;gbkey=CDS;gene_name=OPG074;locus_tag=NBT03_gp053;product=MPXVgp060;protein_id=YP_010377057.1 -NC_063383.1 RefSeq gene 57172 57498 . - . ID=gene-NBT03_gp054;Dbxref=GeneID:72551470;Name=OPG075;gbkey=Gene;gene_name=OPG075;gene_biotype=protein_coding;locus_tag=NBT03_gp054;old_locus_tag=MPXV-M5312_HM12_Rivers-059 -NC_063383.1 RefSeq CDS 57172 57498 . - 0 ID=cds-YP_010377058.1;Parent=gene-NBT03_gp054;Dbxref=Genbank:YP_010377058.1,GeneID:72551470;Name=YP_010377058.1;Note=Q2L%3B similar to Vaccinia virus strain Copenhagen O2L%3B virion-associated glutaredoxin;gbkey=CDS;gene_name=OPG075;locus_tag=NBT03_gp054;product=MPXVgp061;protein_id=YP_010377058.1 -NC_063383.1 RefSeq gene 57523 57630 . - . ID=gene-NBT03_gp055;Dbxref=GeneID:72551471;Name=OPG076;gbkey=Gene;gene_name=OPG076;gene_biotype=protein_coding;locus_tag=NBT03_gp055 -NC_063383.1 RefSeq CDS 57523 57630 . - 0 ID=cds-YP_010377183.1;Parent=gene-NBT03_gp055;Dbxref=Genbank:YP_010377183.1,GeneID:72551471;Name=YP_010377183.1;gbkey=CDS;gene_name=OPG076;locus_tag=NBT03_gp055;product=MV membrane%2C EFC component;protein_id=YP_010377183.1 -NC_063383.1 RefSeq gene 57645 58583 . - . ID=gene-NBT03_gp056;Dbxref=GeneID:72551472;Name=OPG077;gbkey=Gene;gene_name=OPG077;gene_biotype=protein_coding;locus_tag=NBT03_gp056;old_locus_tag=MPXV-M5312_HM12_Rivers-060 -NC_063383.1 RefSeq CDS 57645 58583 . - 0 ID=cds-YP_010377059.1;Parent=gene-NBT03_gp056;Dbxref=Genbank:YP_010377059.1,GeneID:72551472;Name=YP_010377059.1;Note=I1L%3B similar to Vaccinia virus strain Copenhagen I1L%3B virosomal protein essential for virus multiplication;gbkey=CDS;gene_name=OPG077;locus_tag=NBT03_gp056;product=MPXVgp062;protein_id=YP_010377059.1 -NC_063383.1 RefSeq gene 58590 58811 . - . ID=gene-NBT03_gp057;Dbxref=GeneID:72551473;Name=OPG078;gbkey=Gene;gene_name=OPG078;gene_biotype=protein_coding;locus_tag=NBT03_gp057;old_locus_tag=MPXV-M5312_HM12_Rivers-061 -NC_063383.1 RefSeq CDS 58590 58811 . - 0 ID=cds-YP_010377060.1;Parent=gene-NBT03_gp057;Dbxref=Genbank:YP_010377060.1,GeneID:72551473;Name=YP_010377060.1;Note=I2L%3B similar to Vaccinia virus strain Copenhagen I2L;gbkey=CDS;gene_name=OPG078;locus_tag=NBT03_gp057;product=MPXVgp063;protein_id=YP_010377060.1 -NC_063383.1 RefSeq gene 58812 59621 . - . ID=gene-NBT03_gp058;Dbxref=GeneID:72551474;Name=OPG079;gbkey=Gene;gene_name=OPG079;gene_biotype=protein_coding;locus_tag=NBT03_gp058;old_locus_tag=MPXV-M5312_HM12_Rivers-062 -NC_063383.1 RefSeq CDS 58812 59621 . - 0 ID=cds-YP_010377061.1;Parent=gene-NBT03_gp058;Dbxref=Genbank:YP_010377061.1,GeneID:72551474;Name=YP_010377061.1;Note=I3L%3B similar to Vaccinia virus strain Copenhagen I3L%3B virosomal ssDNA-binding phosphoprotein%3B interacts with R2 subunit of ribonucleotide reductase;gbkey=CDS;gene_name=OPG079;locus_tag=NBT03_gp058;product=MPXVgp064;protein_id=YP_010377061.1 -NC_063383.1 RefSeq gene 59703 62018 . - . ID=gene-NBT03_gp059;Dbxref=GeneID:72551475;Name=OPG080;gbkey=Gene;gene_name=OPG080;gene_biotype=protein_coding;locus_tag=NBT03_gp059;old_locus_tag=MPXV-M5312_HM12_Rivers-063 -NC_063383.1 RefSeq CDS 59703 62018 . - 0 ID=cds-YP_010377062.1;Parent=gene-NBT03_gp059;Dbxref=Genbank:YP_010377062.1,GeneID:72551475;Name=YP_010377062.1;Note=I4L%3B similar to Vaccinia virus strain Copenhagen I4L%3B ribonucleotide reductase%2C large subunit%2C R1;gbkey=CDS;gene_name=OPG080;locus_tag=NBT03_gp059;product=MPXVgp065;protein_id=YP_010377062.1 -NC_063383.1 RefSeq gene 62046 62285 . - . ID=gene-NBT03_gp060;Dbxref=GeneID:72551476;Name=OPG081;gbkey=Gene;gene_name=OPG081;gene_biotype=protein_coding;locus_tag=NBT03_gp060;old_locus_tag=MPXV-M5312_HM12_Rivers-064 -NC_063383.1 RefSeq CDS 62046 62285 . - 0 ID=cds-YP_010377063.1;Parent=gene-NBT03_gp060;Dbxref=Genbank:YP_010377063.1,GeneID:72551476;Name=YP_010377063.1;Note=I5L%3B similar to Vaccinia virus strain Copenhagen I5L%3B IMV surface membrane protein;gbkey=CDS;gene_name=OPG081;locus_tag=NBT03_gp060;product=MPXVgp066;protein_id=YP_010377063.1 -NC_063383.1 RefSeq gene 62304 63452 . - . ID=gene-NBT03_gp061;Dbxref=GeneID:72551477;Name=OPG082;gbkey=Gene;gene_name=OPG082;gene_biotype=protein_coding;locus_tag=NBT03_gp061;old_locus_tag=MPXV-M5312_HM12_Rivers-065 -NC_063383.1 RefSeq CDS 62304 63452 . - 0 ID=cds-YP_010377064.1;Parent=gene-NBT03_gp061;Dbxref=Genbank:YP_010377064.1,GeneID:72551477;Name=YP_010377064.1;Note=I6L%3B similar to Vaccinia virus strain Copenhagen I6L;gbkey=CDS;gene_name=OPG082;locus_tag=NBT03_gp061;product=MPXVgp067;protein_id=YP_010377064.1 -NC_063383.1 RefSeq gene 63445 64716 . - . ID=gene-NBT03_gp062;Dbxref=GeneID:72551478;Name=OPG083;gbkey=Gene;gene_name=OPG083;gene_biotype=protein_coding;locus_tag=NBT03_gp062;old_locus_tag=MPXV-M5312_HM12_Rivers-066 -NC_063383.1 RefSeq CDS 63445 64716 . - 0 ID=cds-YP_010377065.1;Parent=gene-NBT03_gp062;Dbxref=Genbank:YP_010377065.1,GeneID:72551478;Name=YP_010377065.1;Note=I7L%3B similar to Vaccinia virus strain Copenhagen I7L%3B virion core protein%3B similar to DNA topoisomerase II;gbkey=CDS;gene_name=OPG083;locus_tag=NBT03_gp062;product=MPXVgp068;protein_id=YP_010377065.1 -NC_063383.1 RefSeq gene 64722 66752 . + . ID=gene-NBT03_gp063;Dbxref=GeneID:72551479;Name=OPG084;gbkey=Gene;gene_name=OPG084;gene_biotype=protein_coding;locus_tag=NBT03_gp063;old_locus_tag=MPXV-M5312_HM12_Rivers-067 -NC_063383.1 RefSeq CDS 64722 66752 . + 0 ID=cds-YP_010377066.1;Parent=gene-NBT03_gp063;Dbxref=Genbank:YP_010377066.1,GeneID:72551479;Name=YP_010377066.1;Note=I8R%3B similar to Vaccinia virus strain Copenhagen I8R%3B nucleoside triphosphate phosphohydrolase II%2C NPH-II%3B DNA and RNA helicase;gbkey=CDS;gene_name=OPG084;locus_tag=NBT03_gp063;product=MPXVgp069;protein_id=YP_010377066.1 -NC_063383.1 RefSeq gene 66756 68531 . - . ID=gene-NBT03_gp064;Dbxref=GeneID:72551480;Name=OPG085;gbkey=Gene;gene_name=OPG085;gene_biotype=protein_coding;locus_tag=NBT03_gp064;old_locus_tag=MPXV-M5312_HM12_Rivers-068 -NC_063383.1 RefSeq CDS 66756 68531 . - 0 ID=cds-YP_010377067.1;Parent=gene-NBT03_gp064;Dbxref=Genbank:YP_010377067.1,GeneID:72551480;Name=YP_010377067.1;Note=G1L%3B similar to Vaccinia virus strain Copenhagen G1L%3B proteinase;gbkey=CDS;gene_name=OPG085;locus_tag=NBT03_gp064;product=MPXVgp070;protein_id=YP_010377067.1 -NC_063383.1 RefSeq gene 68528 68863 . - . ID=gene-NBT03_gp065;Dbxref=GeneID:72551481;Name=OPG086;gbkey=Gene;gene_name=OPG086;gene_biotype=protein_coding;locus_tag=NBT03_gp065;old_locus_tag=MPXV-M5312_HM12_Rivers-069 -NC_063383.1 RefSeq CDS 68528 68863 . - 0 ID=cds-YP_010377068.1;Parent=gene-NBT03_gp065;Dbxref=Genbank:YP_010377068.1,GeneID:72551481;Name=YP_010377068.1;Note=G2L%3B similar to Vaccinia virus strain Copenhagen G3L;gbkey=CDS;gene_name=OPG086;locus_tag=NBT03_gp065;product=MPXVgp071;protein_id=YP_010377068.1 -NC_063383.1 RefSeq gene 68857 69519 . + . ID=gene-NBT03_gp066;Dbxref=GeneID:72551482;Name=OPG087;gbkey=Gene;gene_name=OPG087;gene_biotype=protein_coding;locus_tag=NBT03_gp066;old_locus_tag=MPXV-M5312_HM12_Rivers-070 -NC_063383.1 RefSeq CDS 68857 69519 . + 0 ID=cds-YP_010377069.1;Parent=gene-NBT03_gp066;Dbxref=Genbank:YP_010377069.1,GeneID:72551482;Name=YP_010377069.1;Note=G3R%3B similar to Vaccinia virus strain Copenhagen G2R;gbkey=CDS;gene_name=OPG087;locus_tag=NBT03_gp066;product=MPXVgp072;protein_id=YP_010377069.1 -NC_063383.1 RefSeq gene 69489 69863 . - . ID=gene-NBT03_gp067;Dbxref=GeneID:72551483;Name=OPG088;gbkey=Gene;gene_name=OPG088;gene_biotype=protein_coding;locus_tag=NBT03_gp067;old_locus_tag=MPXV-M5312_HM12_Rivers-071 -NC_063383.1 RefSeq CDS 69489 69863 . - 0 ID=cds-YP_010377070.1;Parent=gene-NBT03_gp067;Dbxref=Genbank:YP_010377070.1,GeneID:72551483;Name=YP_010377070.1;Note=G4L%3B similar to Vaccinia virus strain Copenhagen G4L%3B virion-associated glutaredoxin;gbkey=CDS;gene_name=OPG088;locus_tag=NBT03_gp067;product=MPXVgp073;protein_id=YP_010377070.1 -NC_063383.1 RefSeq gene 69866 71170 . + . ID=gene-NBT03_gp068;Dbxref=GeneID:72551484;Name=OPG089;gbkey=Gene;gene_name=OPG089;gene_biotype=protein_coding;locus_tag=NBT03_gp068;old_locus_tag=MPXV-M5312_HM12_Rivers-072 -NC_063383.1 RefSeq CDS 69866 71170 . + 0 ID=cds-YP_010377071.1;Parent=gene-NBT03_gp068;Dbxref=Genbank:YP_010377071.1,GeneID:72551484;Name=YP_010377071.1;Note=G5R%3B similar to Vaccinia virus strain Copenhagen G5R;gbkey=CDS;gene_name=OPG089;locus_tag=NBT03_gp068;product=MPXVgp074;protein_id=YP_010377071.1 -NC_063383.1 RefSeq gene 71179 71370 . + . ID=gene-NBT03_gp069;Dbxref=GeneID:72551485;Name=OPG090;gbkey=Gene;gene_name=OPG090;gene_biotype=protein_coding;locus_tag=NBT03_gp069;old_locus_tag=MPXV-M5312_HM12_Rivers-073 -NC_063383.1 RefSeq CDS 71179 71370 . + 0 ID=cds-YP_010377072.1;Parent=gene-NBT03_gp069;Dbxref=Genbank:YP_010377072.1,GeneID:72551485;Name=YP_010377072.1;Note=G6R%3B RNA polymerase%2C 7 kDa subunit;gbkey=CDS;gene_name=OPG090;locus_tag=NBT03_gp069;product=MPXVgp075;protein_id=YP_010377072.1 -NC_063383.1 RefSeq gene 71370 71867 . + . ID=gene-NBT03_gp070;Dbxref=GeneID:72551486;Name=OPG091;gbkey=Gene;gene_name=OPG091;gene_biotype=protein_coding;locus_tag=NBT03_gp070;old_locus_tag=MPXV-M5312_HM12_Rivers-074 -NC_063383.1 RefSeq CDS 71370 71867 . + 0 ID=cds-YP_010377073.1;Parent=gene-NBT03_gp070;Dbxref=Genbank:YP_010377073.1,GeneID:72551486;Name=YP_010377073.1;Note=G7R%3B similar to Vaccinia virus strain Copenhagen G6R;gbkey=CDS;gene_name=OPG091;locus_tag=NBT03_gp070;product=MPXVgp076;protein_id=YP_010377073.1 -NC_063383.1 RefSeq gene 71832 72947 . - . ID=gene-NBT03_gp071;Dbxref=GeneID:72551487;Name=OPG092;gbkey=Gene;gene_name=OPG092;gene_biotype=protein_coding;locus_tag=NBT03_gp071;old_locus_tag=MPXV-M5312_HM12_Rivers-075 -NC_063383.1 RefSeq CDS 71832 72947 . - 0 ID=cds-YP_010377074.1;Parent=gene-NBT03_gp071;Dbxref=Genbank:YP_010377074.1,GeneID:72551487;Name=YP_010377074.1;Note=G8L%3B similar to Vaccinia virus strain Copenhagen G7L%3B virion protein;gbkey=CDS;gene_name=OPG092;locus_tag=NBT03_gp071;product=MPXVgp077;protein_id=YP_010377074.1 -NC_063383.1 RefSeq gene 72978 73760 . + . ID=gene-NBT03_gp072;Dbxref=GeneID:72551488;Name=OPG093;gbkey=Gene;gene_name=OPG093;gene_biotype=protein_coding;locus_tag=NBT03_gp072;old_locus_tag=MPXV-M5312_HM12_Rivers-076 -NC_063383.1 RefSeq CDS 72978 73760 . + 0 ID=cds-YP_010377075.1;Parent=gene-NBT03_gp072;Dbxref=Genbank:YP_010377075.1,GeneID:72551488;Name=YP_010377075.1;Note=G9R%3B similar to Vaccinia virus strain Copenhagen G8R%3B late gene transcription factor%2C VLTF-1;gbkey=CDS;gene_name=OPG093;locus_tag=NBT03_gp072;product=MPXVgp078;protein_id=YP_010377075.1 -NC_063383.1 RefSeq gene 73780 74802 . + . ID=gene-NBT03_gp073;Dbxref=GeneID:72551489;Name=OPG094;gbkey=Gene;gene_name=OPG094;gene_biotype=protein_coding;locus_tag=NBT03_gp073;old_locus_tag=MPXV-M5312_HM12_Rivers-077 -NC_063383.1 RefSeq CDS 73780 74802 . + 0 ID=cds-YP_010377076.1;Parent=gene-NBT03_gp073;Dbxref=Genbank:YP_010377076.1,GeneID:72551489;Name=YP_010377076.1;Note=G10R%3B similar to Vaccinia virus strain Copenhagen G9R%3B myristylated protein;gbkey=CDS;gene_name=OPG094;locus_tag=NBT03_gp073;product=MPXVgp079;protein_id=YP_010377076.1 -NC_063383.1 RefSeq gene 74803 75555 . + . ID=gene-NBT03_gp074;Dbxref=GeneID:72551490;Name=OPG095;gbkey=Gene;gene_name=OPG095;gene_biotype=protein_coding;locus_tag=NBT03_gp074;old_locus_tag=MPXV-M5312_HM12_Rivers-078 -NC_063383.1 RefSeq CDS 74803 75555 . + 0 ID=cds-YP_010377077.1;Parent=gene-NBT03_gp074;Dbxref=Genbank:YP_010377077.1,GeneID:72551490;Name=YP_010377077.1;Note=M1R%3B similar to Vaccinia virus strain Copenhagen L1R%3B myristylated IMV surface membrane protein;gbkey=CDS;gene_name=OPG095;locus_tag=NBT03_gp074;product=MPXVgp080;protein_id=YP_010377077.1 -NC_063383.1 RefSeq gene 75587 75865 . + . ID=gene-NBT03_gp075;Dbxref=GeneID:72551491;Name=OPG096;gbkey=Gene;gene_name=OPG096;gene_biotype=protein_coding;locus_tag=NBT03_gp075;old_locus_tag=MPXV-M5312_HM12_Rivers-079 -NC_063383.1 RefSeq CDS 75587 75865 . + 0 ID=cds-YP_010377078.1;Parent=gene-NBT03_gp075;Dbxref=Genbank:YP_010377078.1,GeneID:72551491;Name=YP_010377078.1;Note=M2R%3B similar to Vaccinia virus strain Copenhagen L2R;gbkey=CDS;gene_name=OPG096;locus_tag=NBT03_gp075;product=MPXVgp081;protein_id=YP_010377078.1 -NC_063383.1 RefSeq gene 75841 76875 . - . ID=gene-NBT03_gp076;Dbxref=GeneID:72551492;Name=OPG097;gbkey=Gene;gene_name=OPG097;gene_biotype=protein_coding;locus_tag=NBT03_gp076;old_locus_tag=MPXV-M5312_HM12_Rivers-080 -NC_063383.1 RefSeq CDS 75841 76875 . - 0 ID=cds-YP_010377079.1;Parent=gene-NBT03_gp076;Dbxref=Genbank:YP_010377079.1,GeneID:72551492;Name=YP_010377079.1;Note=M3L%3B similar to Vaccinia virus strain Copenhagen L3L;gbkey=CDS;gene_name=OPG097;locus_tag=NBT03_gp076;product=MPXVgp082;protein_id=YP_010377079.1 -NC_063383.1 RefSeq gene 76900 77655 . + . ID=gene-NBT03_gp077;Dbxref=GeneID:72551493;Name=OPG098;gbkey=Gene;gene_name=OPG098;gene_biotype=protein_coding;locus_tag=NBT03_gp077;old_locus_tag=MPXV-M5312_HM12_Rivers-081 -NC_063383.1 RefSeq CDS 76900 77655 . + 0 ID=cds-YP_010377080.1;Parent=gene-NBT03_gp077;Dbxref=Genbank:YP_010377080.1,GeneID:72551493;Name=YP_010377080.1;Note=M4R%3B similar to Vaccinia virus strain Copenhagen L4R%3B virion core protein%3B ssDNA binding%3B stimulation of I8R helicase activity;gbkey=CDS;gene_name=OPG098;locus_tag=NBT03_gp077;product=MPXVgp083;protein_id=YP_010377080.1 -NC_063383.1 RefSeq gene 77665 78051 . + . ID=gene-NBT03_gp078;Dbxref=GeneID:72551494;Name=OPG099;gbkey=Gene;gene_name=OPG099;gene_biotype=protein_coding;locus_tag=NBT03_gp078;old_locus_tag=MPXV-M5312_HM12_Rivers-082 -NC_063383.1 RefSeq CDS 77665 78051 . + 0 ID=cds-YP_010377081.1;Parent=gene-NBT03_gp078;Dbxref=Genbank:YP_010377081.1,GeneID:72551494;Name=YP_010377081.1;Note=M5R%3B similar to Vaccinia virus strain Copenhagen L5R;gbkey=CDS;gene_name=OPG099;locus_tag=NBT03_gp078;product=MPXVgp084;protein_id=YP_010377081.1 -NC_063383.1 RefSeq gene 78008 78466 . + . ID=gene-NBT03_gp079;Dbxref=GeneID:72551495;Name=OPG100;gbkey=Gene;gene_name=OPG100;gene_biotype=protein_coding;locus_tag=NBT03_gp079;old_locus_tag=MPXV-M5312_HM12_Rivers-083 -NC_063383.1 RefSeq CDS 78008 78466 . + 0 ID=cds-YP_010377082.1;Parent=gene-NBT03_gp079;Dbxref=Genbank:YP_010377082.1,GeneID:72551495;Name=YP_010377082.1;Note=L1R%3B similar to Vaccinia virus strain Copenhagen J1R;gbkey=CDS;gene_name=OPG100;locus_tag=NBT03_gp079;product=MPXVgp085;protein_id=YP_010377082.1 -NC_063383.1 RefSeq gene 78486 79019 . + . ID=gene-NBT03_gp080;Dbxref=GeneID:72551496;Name=OPG101;gbkey=Gene;gene_name=OPG101;gene_biotype=protein_coding;locus_tag=NBT03_gp080;old_locus_tag=MPXV-M5312_HM12_Rivers-084 -NC_063383.1 RefSeq CDS 78486 79019 . + 0 ID=cds-YP_010377083.1;Parent=gene-NBT03_gp080;Dbxref=Genbank:YP_010377083.1,GeneID:72551496;Name=YP_010377083.1;Note=L2R%3B similar to Vaccinia virus strain Copenhagen J2R%3B thymidine kinase;gbkey=CDS;gene_name=OPG101;locus_tag=NBT03_gp080;product=MPXVgp086;protein_id=YP_010377083.1 -NC_063383.1 RefSeq gene 79085 80086 . + . ID=gene-NBT03_gp081;Dbxref=GeneID:72551497;Name=OPG102;gbkey=Gene;gene_name=OPG102;gene_biotype=protein_coding;locus_tag=NBT03_gp081;old_locus_tag=MPXV-M5312_HM12_Rivers-085 -NC_063383.1 RefSeq CDS 79085 80086 . + 0 ID=cds-YP_010377084.1;Parent=gene-NBT03_gp081;Dbxref=Genbank:YP_010377084.1,GeneID:72551497;Name=YP_010377084.1;Note=L3R%3B similar to Vaccinia virus strain Copenhagen J3R%3B poly-A polymerase%2C stimulatory subunit%2C simultaneously cap-specific mRNA (nucleoside-O2'-)-methyltransferase;gbkey=CDS;gene_name=OPG102;locus_tag=NBT03_gp081;product=MPXVgp087;protein_id=YP_010377084.1 -NC_063383.1 RefSeq gene 80001 80558 . + . ID=gene-NBT03_gp082;Dbxref=GeneID:72551498;Name=OPG103;gbkey=Gene;gene_name=OPG103;gene_biotype=protein_coding;locus_tag=NBT03_gp082;old_locus_tag=MPXV-M5312_HM12_Rivers-086 -NC_063383.1 RefSeq CDS 80001 80558 . + 0 ID=cds-YP_010377085.1;Parent=gene-NBT03_gp082;Dbxref=Genbank:YP_010377085.1,GeneID:72551498;Name=YP_010377085.1;Note=L4R%3B similar to Vaccinia virus strain Copenhagen J4R%3B RNA polymerase%2C 22 kDa subunit;gbkey=CDS;gene_name=OPG103;locus_tag=NBT03_gp082;product=MPXVgp088;protein_id=YP_010377085.1 -NC_063383.1 RefSeq gene 80618 81019 . - . ID=gene-NBT03_gp083;Dbxref=GeneID:72551499;Name=OPG104;gbkey=Gene;gene_name=OPG104;gene_biotype=protein_coding;locus_tag=NBT03_gp083;old_locus_tag=MPXV-M5312_HM12_Rivers-087 -NC_063383.1 RefSeq CDS 80618 81019 . - 0 ID=cds-YP_010377086.1;Parent=gene-NBT03_gp083;Dbxref=Genbank:YP_010377086.1,GeneID:72551499;Name=YP_010377086.1;Note=L5L%3B similar to Vaccinia virus strain Copenhagen J5L%3B essential for virus multiplication;gbkey=CDS;gene_name=OPG104;locus_tag=NBT03_gp083;product=MPXVgp089;protein_id=YP_010377086.1 -NC_063383.1 RefSeq gene 81126 84986 . + . ID=gene-NBT03_gp084;Dbxref=GeneID:72551500;Name=OPG105;gbkey=Gene;gene_name=OPG105;gene_biotype=protein_coding;locus_tag=NBT03_gp084;old_locus_tag=MPXV-M5312_HM12_Rivers-088 -NC_063383.1 RefSeq CDS 81126 84986 . + 0 ID=cds-YP_010377087.1;Parent=gene-NBT03_gp084;Dbxref=Genbank:YP_010377087.1,GeneID:72551500;Name=YP_010377087.1;Note=L6R%3B similar to Vaccinia virus strain Copenhagen J6R%3B RNA polymerase%2C 147 kDa subunit;gbkey=CDS;gene_name=OPG105;locus_tag=NBT03_gp084;product=MPXVgp090;protein_id=YP_010377087.1 -NC_063383.1 RefSeq gene 84983 85498 . - . ID=gene-NBT03_gp085;Dbxref=GeneID:72551501;Name=OPG106;gbkey=Gene;gene_name=OPG106;gene_biotype=protein_coding;locus_tag=NBT03_gp085;old_locus_tag=MPXV-M5312_HM12_Rivers-089 -NC_063383.1 RefSeq CDS 84983 85498 . - 0 ID=cds-YP_010377088.1;Parent=gene-NBT03_gp085;Dbxref=Genbank:YP_010377088.1,GeneID:72551501;Name=YP_010377088.1;Note=H1L%3B similar to Vaccinia virus strain Copenhagen H1L%3B tyrosine;gbkey=CDS;gene_name=OPG106;locus_tag=NBT03_gp085;product=MPXVgp091;protein_id=YP_010377088.1 -NC_063383.1 RefSeq gene 85512 86081 . + . ID=gene-NBT03_gp086;Dbxref=GeneID:72551502;Name=OPG107;gbkey=Gene;gene_name=OPG107;gene_biotype=protein_coding;locus_tag=NBT03_gp086;old_locus_tag=MPXV-M5312_HM12_Rivers-090 -NC_063383.1 RefSeq CDS 85512 86081 . + 0 ID=cds-YP_010377089.1;Parent=gene-NBT03_gp086;Dbxref=Genbank:YP_010377089.1,GeneID:72551502;Name=YP_010377089.1;Note=H2R%3B similar to Vaccinia virus strain Copenhagen H2R;gbkey=CDS;gene_name=OPG107;locus_tag=NBT03_gp086;product=MPXVgp092;protein_id=YP_010377089.1 -NC_063383.1 RefSeq gene 86085 87059 . - . ID=gene-NBT03_gp087;Dbxref=GeneID:72551503;Name=OPG108;gbkey=Gene;gene_name=OPG108;gene_biotype=protein_coding;locus_tag=NBT03_gp087;old_locus_tag=MPXV-M5312_HM12_Rivers-091 -NC_063383.1 RefSeq CDS 86085 87059 . - 0 ID=cds-YP_010377090.1;Parent=gene-NBT03_gp087;Dbxref=Genbank:YP_010377090.1,GeneID:72551503;Name=YP_010377090.1;Note=H3L%3B similar to Vaccinia virus strain Copenhagen H3L%3B IMV surface membrane protein;gbkey=CDS;gene_name=OPG108;locus_tag=NBT03_gp087;product=MPXVgp093;protein_id=YP_010377090.1 -NC_063383.1 RefSeq gene 87060 89447 . - . ID=gene-NBT03_gp088;Dbxref=GeneID:72551504;Name=OPG109;gbkey=Gene;gene_name=OPG109;gene_biotype=protein_coding;locus_tag=NBT03_gp088;old_locus_tag=MPXV-M5312_HM12_Rivers-092 -NC_063383.1 RefSeq CDS 87060 89447 . - 0 ID=cds-YP_010377091.1;Parent=gene-NBT03_gp088;Dbxref=Genbank:YP_010377091.1,GeneID:72551504;Name=YP_010377091.1;Note=H4L%3B similar to Vaccinia virus strain Copenhagen H4L%3B virion core RNA polymerase-associated protein%2C RAP94;gbkey=CDS;gene_name=OPG109;locus_tag=NBT03_gp088;product=MPXVgp094;protein_id=YP_010377091.1 -NC_063383.1 RefSeq gene 89632 90264 . + . ID=gene-NBT03_gp089;Dbxref=GeneID:72551505;Name=OPG110;gbkey=Gene;gene_name=OPG110;gene_biotype=protein_coding;locus_tag=NBT03_gp089;old_locus_tag=MPXV-M5312_HM12_Rivers-093 -NC_063383.1 RefSeq CDS 89632 90264 . + 0 ID=cds-YP_010377092.1;Parent=gene-NBT03_gp089;Dbxref=Genbank:YP_010377092.1,GeneID:72551505;Name=YP_010377092.1;Note=H5R%3B similar to Vaccinia virus strain Copenhagen H5R%3B virosome-associated late gene transcription factor%2C VLTF-4%3B Ca2+-binding motif;gbkey=CDS;gene_name=OPG110;locus_tag=NBT03_gp089;product=MPXVgp095;protein_id=YP_010377092.1 -NC_063383.1 RefSeq gene 90265 91209 . + . ID=gene-NBT03_gp090;Dbxref=GeneID:72551506;Name=OPG111;gbkey=Gene;gene_name=OPG111;gene_biotype=protein_coding;locus_tag=NBT03_gp090;old_locus_tag=MPXV-M5312_HM12_Rivers-094 -NC_063383.1 RefSeq CDS 90265 91209 . + 0 ID=cds-YP_010377093.1;Parent=gene-NBT03_gp090;Dbxref=Genbank:YP_010377093.1,GeneID:72551506;Name=YP_010377093.1;Note=H6R%3B similar to Vaccinia virus strain Copenhagen H6R%3B DNA topoisomerase;gbkey=CDS;gene_name=OPG111;locus_tag=NBT03_gp090;product=MPXVgp096;protein_id=YP_010377093.1 -NC_063383.1 RefSeq gene 91247 91687 . + . ID=gene-NBT03_gp091;Dbxref=GeneID:72551507;Name=OPG112;gbkey=Gene;gene_name=OPG112;gene_biotype=protein_coding;locus_tag=NBT03_gp091;old_locus_tag=MPXV-M5312_HM12_Rivers-095 -NC_063383.1 RefSeq CDS 91247 91687 . + 0 ID=cds-YP_010377094.1;Parent=gene-NBT03_gp091;Dbxref=Genbank:YP_010377094.1,GeneID:72551507;Name=YP_010377094.1;Note=H7R%3B similar to Vaccinia virus strain Copenhagen H7R;gbkey=CDS;gene_name=OPG112;locus_tag=NBT03_gp091;product=MPXVgp097;protein_id=YP_010377094.1 -NC_063383.1 RefSeq gene 91731 94268 . + . ID=gene-NBT03_gp092;Dbxref=GeneID:72551508;Name=OPG113;gbkey=Gene;gene_name=OPG113;gene_biotype=protein_coding;locus_tag=NBT03_gp092;old_locus_tag=MPXV-M5312_HM12_Rivers-096 -NC_063383.1 RefSeq CDS 91731 94268 . + 0 ID=cds-YP_010377095.1;Parent=gene-NBT03_gp092;Dbxref=Genbank:YP_010377095.1,GeneID:72551508;Name=YP_010377095.1;Note=E1R%3B similar to Vaccinia virus strain Copenhagen D1R%3B mRNA capping enzyme%2C large subunit%3B RNA 5' triphosphatase and RNA guanylyl transferase activities;gbkey=CDS;gene_name=OPG113;locus_tag=NBT03_gp092;product=MPXVgp098;protein_id=YP_010377095.1 -NC_063383.1 RefSeq gene 94227 94667 . - . ID=gene-NBT03_gp093;Dbxref=GeneID:72551509;Name=OPG114;gbkey=Gene;gene_name=OPG114;gene_biotype=protein_coding;locus_tag=NBT03_gp093;old_locus_tag=MPXV-M5312_HM12_Rivers-097 -NC_063383.1 RefSeq CDS 94227 94667 . - 0 ID=cds-YP_010377096.1;Parent=gene-NBT03_gp093;Dbxref=Genbank:YP_010377096.1,GeneID:72551509;Name=YP_010377096.1;Note=E2L%3B similar to Vaccinia virus strain Copenhagen D2L%3B virion core protein;gbkey=CDS;gene_name=OPG114;locus_tag=NBT03_gp093;product=MPXVgp099;protein_id=YP_010377096.1 -NC_063383.1 RefSeq gene 94660 95361 . + . ID=gene-NBT03_gp094;Dbxref=GeneID:72551510;Name=OPG115;gbkey=Gene;gene_name=OPG115;gene_biotype=protein_coding;locus_tag=NBT03_gp094;old_locus_tag=MPXV-M5312_HM12_Rivers-098 -NC_063383.1 RefSeq CDS 94660 95361 . + 0 ID=cds-YP_010377097.1;Parent=gene-NBT03_gp094;Dbxref=Genbank:YP_010377097.1,GeneID:72551510;Name=YP_010377097.1;Note=E3R%3B similar to Vaccinia virus strain Copenhagen D3R%3B virion core protein;gbkey=CDS;gene_name=OPG115;locus_tag=NBT03_gp094;product=MPXVgp100;protein_id=YP_010377097.1 -NC_063383.1 RefSeq gene 95361 96017 . + . ID=gene-NBT03_gp095;Dbxref=GeneID:72551511;Name=OPG116;gbkey=Gene;gene_name=OPG116;gene_biotype=protein_coding;locus_tag=NBT03_gp095;old_locus_tag=MPXV-M5312_HM12_Rivers-099 -NC_063383.1 RefSeq CDS 95361 96017 . + 0 ID=cds-YP_010377098.1;Parent=gene-NBT03_gp095;Dbxref=Genbank:YP_010377098.1,GeneID:72551511;Name=YP_010377098.1;Note=E4R%3B similar to Vaccinia virus strain Copenhagen D4R%3B uracil DNA glycosylase;gbkey=CDS;gene_name=OPG116;locus_tag=NBT03_gp095;product=MPXVgp101;protein_id=YP_010377098.1 -NC_063383.1 RefSeq gene 96049 98406 . + . ID=gene-NBT03_gp096;Dbxref=GeneID:72551512;Name=OPG117;gbkey=Gene;gene_name=OPG117;gene_biotype=protein_coding;locus_tag=NBT03_gp096;old_locus_tag=MPXV-M5312_HM12_Rivers-100 -NC_063383.1 RefSeq CDS 96049 98406 . + 0 ID=cds-YP_010377099.1;Parent=gene-NBT03_gp096;Dbxref=Genbank:YP_010377099.1,GeneID:72551512;Name=YP_010377099.1;Note=E5R%3B similar to Vaccinia virus strain Copenhagen D5R%3B nucleic acid-independent nucleoside triphosphatase;gbkey=CDS;gene_name=OPG117;locus_tag=NBT03_gp096;product=MPXVgp102;protein_id=YP_010377099.1 -NC_063383.1 RefSeq gene 98446 100359 . + . ID=gene-NBT03_gp097;Dbxref=GeneID:72551513;Name=OPG118;gbkey=Gene;gene_name=OPG118;gene_biotype=protein_coding;locus_tag=NBT03_gp097;old_locus_tag=MPXV-M5312_HM12_Rivers-101 -NC_063383.1 RefSeq CDS 98446 100359 . + 0 ID=cds-YP_010377100.1;Parent=gene-NBT03_gp097;Dbxref=Genbank:YP_010377100.1,GeneID:72551513;Name=YP_010377100.1;Note=E6R%3B similar to Vaccinia virus strain Copenhagen D6R%3B early transcription factor%2C VETF%2C small subunit;gbkey=CDS;gene_name=OPG118;locus_tag=NBT03_gp097;product=MPXVgp103;protein_id=YP_010377100.1 -NC_063383.1 RefSeq gene 100386 100871 . + . ID=gene-NBT03_gp098;Dbxref=GeneID:72551514;Name=OPG119;gbkey=Gene;gene_name=OPG119;gene_biotype=protein_coding;locus_tag=NBT03_gp098;old_locus_tag=MPXV-M5312_HM12_Rivers-102 -NC_063383.1 RefSeq CDS 100386 100871 . + 0 ID=cds-YP_010377101.1;Parent=gene-NBT03_gp098;Dbxref=Genbank:YP_010377101.1,GeneID:72551514;Name=YP_010377101.1;Note=E7R%3B similar to Vaccinia virus strain Copenhagen D7R%3B RNA polymerase%2C 18 kDa subunit;gbkey=CDS;gene_name=OPG119;locus_tag=NBT03_gp098;product=MPXVgp104;protein_id=YP_010377101.1 -NC_063383.1 RefSeq gene 100834 101748 . - . ID=gene-NBT03_gp099;Dbxref=GeneID:72551515;Name=OPG120;gbkey=Gene;gene_name=OPG120;gene_biotype=protein_coding;locus_tag=NBT03_gp099;old_locus_tag=MPXV-M5312_HM12_Rivers-103 -NC_063383.1 RefSeq CDS 100834 101748 . - 0 ID=cds-YP_010377102.1;Parent=gene-NBT03_gp099;Dbxref=Genbank:YP_010377102.1,GeneID:72551515;Name=YP_010377102.1;Note=E8L%3B similar to Vaccinia virus strain Copenhagen D8L%3B IMV surface membrane 32 kDa protein%3B binding to cell surface chondroitin sulfate%3B IMV adsorption to cell surface;gbkey=CDS;gene_name=OPG120;locus_tag=NBT03_gp099;product=MPXVgp105;protein_id=YP_010377102.1 -NC_063383.1 RefSeq gene 101790 102431 . + . ID=gene-NBT03_gp100;Dbxref=GeneID:72551516;Name=OPG121;gbkey=Gene;gene_name=OPG121;gene_biotype=protein_coding;locus_tag=NBT03_gp100;old_locus_tag=MPXV-M5312_HM12_Rivers-104 -NC_063383.1 RefSeq CDS 101790 102431 . + 0 ID=cds-YP_010377103.1;Parent=gene-NBT03_gp100;Dbxref=Genbank:YP_010377103.1,GeneID:72551516;Name=YP_010377103.1;Note=E9R%3B similar to Vaccinia virus strain Copenhagen D9R%3B Mut-like;gbkey=CDS;gene_name=OPG121;locus_tag=NBT03_gp100;product=MPXVgp106;protein_id=YP_010377103.1 -NC_063383.1 RefSeq gene 102428 103174 . + . ID=gene-NBT03_gp101;Dbxref=GeneID:72551517;Name=OPG122;gbkey=Gene;gene_name=OPG122;gene_biotype=protein_coding;locus_tag=NBT03_gp101;old_locus_tag=MPXV-M5312_HM12_Rivers-105 -NC_063383.1 RefSeq CDS 102428 103174 . + 0 ID=cds-YP_010377104.1;Parent=gene-NBT03_gp101;Dbxref=Genbank:YP_010377104.1,GeneID:72551517;Name=YP_010377104.1;Note=E10R%3B similar to Vaccinia virus strain Copenhagen D10R%3B down regulation of gene expression%3B Mut-like;gbkey=CDS;gene_name=OPG122;locus_tag=NBT03_gp101;product=MPXVgp107;protein_id=YP_010377104.1 -NC_063383.1 RefSeq gene 103175 105070 . - . ID=gene-NBT03_gp102;Dbxref=GeneID:72551518;Name=OPG123;gbkey=Gene;gene_name=OPG123;gene_biotype=protein_coding;locus_tag=NBT03_gp102;old_locus_tag=MPXV-M5312_HM12_Rivers-106 -NC_063383.1 RefSeq CDS 103175 105070 . - 0 ID=cds-YP_010377105.1;Parent=gene-NBT03_gp102;Dbxref=Genbank:YP_010377105.1,GeneID:72551518;Name=YP_010377105.1;Note=E11L%3B similar to Vaccinia virus strain Copenhagen D11L%3B nucleoside triphosphate phosphohydrolase I%2C NPH I%3B DNA-dependent ATPase%3B early gene transcription termination factor;gbkey=CDS;gene_name=OPG123;locus_tag=NBT03_gp102;product=MPXVgp108;protein_id=YP_010377105.1 -NC_063383.1 RefSeq gene 105105 105968 . - . ID=gene-NBT03_gp103;Dbxref=GeneID:72551519;Name=OPG124;gbkey=Gene;gene_name=OPG124;gene_biotype=protein_coding;locus_tag=NBT03_gp103;old_locus_tag=MPXV-M5312_HM12_Rivers-107 -NC_063383.1 RefSeq CDS 105105 105968 . - 0 ID=cds-YP_010377106.1;Parent=gene-NBT03_gp103;Dbxref=Genbank:YP_010377106.1,GeneID:72551519;Name=YP_010377106.1;Note=E12L%3B similar to Vaccinia virus strain Copenhagen D12L%3B mRNA capping enzyme%2C small subunit%3B mRNA (guanine-N7-)-methyl-transferase%3B transcription initiation factor;gbkey=CDS;gene_name=OPG124;locus_tag=NBT03_gp103;product=MPXVgp109;protein_id=YP_010377106.1 -NC_063383.1 RefSeq gene 105999 107654 . - . ID=gene-NBT03_gp104;Dbxref=GeneID:72551520;Name=OPG125;gbkey=Gene;gene_name=OPG125;gene_biotype=protein_coding;locus_tag=NBT03_gp104;old_locus_tag=MPXV-M5312_HM12_Rivers-108 -NC_063383.1 RefSeq CDS 105999 107654 . - 0 ID=cds-YP_010377107.1;Parent=gene-NBT03_gp104;Dbxref=Genbank:YP_010377107.1,GeneID:72551520;Name=YP_010377107.1;Note=E13L%3B similar to Vaccinia virus strain Copenhagen D13L%3B protein needed for the formation of immature IMV surface membrane;gbkey=CDS;gene_name=OPG125;locus_tag=NBT03_gp104;product=MPXVgp110;protein_id=YP_010377107.1 -NC_063383.1 RefSeq gene 107678 108130 . - . ID=gene-NBT03_gp105;Dbxref=GeneID:72551521;Name=OPG126;gbkey=Gene;gene_name=OPG126;gene_biotype=protein_coding;locus_tag=NBT03_gp105;old_locus_tag=MPXV-M5312_HM12_Rivers-109 -NC_063383.1 RefSeq CDS 107678 108130 . - 0 ID=cds-YP_010377108.1;Parent=gene-NBT03_gp105;Dbxref=Genbank:YP_010377108.1,GeneID:72551521;Name=YP_010377108.1;Note=A1L%3B similar to Vaccinia virus strain Copenhagen A1L%3B late gene transcription factor%2C VLTF-2;gbkey=CDS;gene_name=OPG126;locus_tag=NBT03_gp105;product=MPXVgp111;protein_id=YP_010377108.1 -NC_063383.1 RefSeq gene 108151 108825 . - . ID=gene-NBT03_gp106;Dbxref=GeneID:72551522;Name=OPG127;gbkey=Gene;gene_name=OPG127;gene_biotype=protein_coding;locus_tag=NBT03_gp106;old_locus_tag=MPXV-M5312_HM12_Rivers-110 -NC_063383.1 RefSeq CDS 108151 108825 . - 0 ID=cds-YP_010377109.1;Parent=gene-NBT03_gp106;Dbxref=Genbank:YP_010377109.1,GeneID:72551522;Name=YP_010377109.1;Note=A2L%3B similar to Vaccinia virus strain Copenhagen A2L%3B late gene transcription factor%2C VLTF-3%3B zinc binding;gbkey=CDS;gene_name=OPG127;locus_tag=NBT03_gp106;product=MPXVgp112;protein_id=YP_010377109.1 -NC_063383.1 RefSeq gene 108822 109055 . - . ID=gene-NBT03_gp107;Dbxref=GeneID:72551523;Name=OPG128;gbkey=Gene;gene_name=OPG128;gene_biotype=protein_coding;locus_tag=NBT03_gp107;old_locus_tag=MPXV-M5312_HM12_Rivers-111 -NC_063383.1 RefSeq CDS 108822 109055 . - 0 ID=cds-YP_010377110.1;Parent=gene-NBT03_gp107;Dbxref=Genbank:YP_010377110.1,GeneID:72551523;Name=YP_010377110.1;Note=A3L;gbkey=CDS;gene_name=OPG128;locus_tag=NBT03_gp107;product=MPXVgp113;protein_id=YP_010377110.1 -NC_063383.1 RefSeq gene 109070 111004 . - . ID=gene-NBT03_gp108;Dbxref=GeneID:72551524;Name=OPG129;gbkey=Gene;gene_name=OPG129;gene_biotype=protein_coding;locus_tag=NBT03_gp108;old_locus_tag=MPXV-M5312_HM12_Rivers-112 -NC_063383.1 RefSeq CDS 109070 111004 . - 0 ID=cds-YP_010377111.1;Parent=gene-NBT03_gp108;Dbxref=Genbank:YP_010377111.1,GeneID:72551524;Name=YP_010377111.1;Note=A4L%3B similar to Vaccinia virus strain Copenhagen A3L%3B major virion core protein p4b;gbkey=CDS;gene_name=OPG129;locus_tag=NBT03_gp108;product=MPXVgp114;protein_id=YP_010377111.1 -NC_063383.1 RefSeq gene 111057 111902 . - . ID=gene-NBT03_gp109;Dbxref=GeneID:72551525;Name=OPG130;gbkey=Gene;gene_name=OPG130;gene_biotype=protein_coding;locus_tag=NBT03_gp109;old_locus_tag=MPXV-M5312_HM12_Rivers-113 -NC_063383.1 RefSeq CDS 111057 111902 . - 0 ID=cds-YP_010377112.1;Parent=gene-NBT03_gp109;Dbxref=Genbank:YP_010377112.1,GeneID:72551525;Name=YP_010377112.1;Note=A5L%3B similar to Vaccinia virus strain Copenhagen A4L%3B 39 kDa immunodominant virion core protein needed for the progression of IV to infectious IMV;gbkey=CDS;gene_name=OPG130;locus_tag=NBT03_gp109;product=MPXVgp115;protein_id=YP_010377112.1 -NC_063383.1 RefSeq gene 111940 112425 . + . ID=gene-NBT03_gp110;Dbxref=GeneID:72551526;Name=OPG131;gbkey=Gene;gene_name=OPG131;gene_biotype=protein_coding;locus_tag=NBT03_gp110;old_locus_tag=MPXV-M5312_HM12_Rivers-114 -NC_063383.1 RefSeq CDS 111940 112425 . + 0 ID=cds-YP_010377113.1;Parent=gene-NBT03_gp110;Dbxref=Genbank:YP_010377113.1,GeneID:72551526;Name=YP_010377113.1;Note=A6R%3B similar to Vaccinia virus strain Copenhagen A5R%3B precursor of RNA polymerase 22 kDa and 21 kDa;gbkey=CDS;gene_name=OPG131;locus_tag=NBT03_gp110;product=MPXVgp116;protein_id=YP_010377113.1 -NC_063383.1 RefSeq gene 112422 113540 . - . ID=gene-NBT03_gp111;Dbxref=GeneID:72551527;Name=OPG132;gbkey=Gene;gene_name=OPG132;gene_biotype=protein_coding;locus_tag=NBT03_gp111;old_locus_tag=MPXV-M5312_HM12_Rivers-115 -NC_063383.1 RefSeq CDS 112422 113540 . - 0 ID=cds-YP_010377114.1;Parent=gene-NBT03_gp111;Dbxref=Genbank:YP_010377114.1,GeneID:72551527;Name=YP_010377114.1;Note=A7L%3B similar to Vaccinia virus strain Copenhagen A6L;gbkey=CDS;gene_name=OPG132;locus_tag=NBT03_gp111;product=MPXVgp117;protein_id=YP_010377114.1 -NC_063383.1 RefSeq gene 113564 115696 . - . ID=gene-NBT03_gp112;Dbxref=GeneID:72551528;Name=OPG133;gbkey=Gene;gene_name=OPG133;gene_biotype=protein_coding;locus_tag=NBT03_gp112;old_locus_tag=MPXV-M5312_HM12_Rivers-116 -NC_063383.1 RefSeq CDS 113564 115696 . - 0 ID=cds-YP_010377115.1;Parent=gene-NBT03_gp112;Dbxref=Genbank:YP_010377115.1,GeneID:72551528;Name=YP_010377115.1;Note=A8L%3B similar to Vaccinia virus strain Copenhagen A7L%3B early transcription factor%2C VETF%2C large subunit%3B needed for morphogenesis of the virion core;gbkey=CDS;gene_name=OPG133;locus_tag=NBT03_gp112;product=MPXVgp118;protein_id=YP_010377115.1 -NC_063383.1 RefSeq gene 115750 116628 . + . ID=gene-NBT03_gp113;Dbxref=GeneID:72551529;Name=OPG134;gbkey=Gene;gene_name=OPG134;gene_biotype=protein_coding;locus_tag=NBT03_gp113;old_locus_tag=MPXV-M5312_HM12_Rivers-117 -NC_063383.1 RefSeq CDS 115750 116628 . + 0 ID=cds-YP_010377116.1;Parent=gene-NBT03_gp113;Dbxref=Genbank:YP_010377116.1,GeneID:72551529;Name=YP_010377116.1;Note=A9R%3B similar to Vaccinia virus strain Copenhagen A8R%3B intermediate transcription factor%2C VITF-3%2C 34 kDa;gbkey=CDS;gene_name=OPG134;locus_tag=NBT03_gp113;product=MPXVgp119;protein_id=YP_010377116.1 -NC_063383.1 RefSeq gene 116609 116911 . - . ID=gene-NBT03_gp114;Dbxref=GeneID:72551530;Name=OPG135;gbkey=Gene;gene_name=OPG135;gene_biotype=protein_coding;locus_tag=NBT03_gp114;old_locus_tag=MPXV-M5312_HM12_Rivers-118 -NC_063383.1 RefSeq CDS 116609 116911 . - 0 ID=cds-YP_010377117.1;Parent=gene-NBT03_gp114;Dbxref=Genbank:YP_010377117.1,GeneID:72551530;Name=YP_010377117.1;Note=A10L%3B similar to Vaccinia virus strain Copenhagen A9L;gbkey=CDS;gene_name=OPG135;locus_tag=NBT03_gp114;product=MPXVgp120;protein_id=YP_010377117.1 -NC_063383.1 RefSeq gene 116912 119587 . - . ID=gene-NBT03_gp115;Dbxref=GeneID:72551531;Name=OPG136;gbkey=Gene;gene_name=OPG136;gene_biotype=protein_coding;locus_tag=NBT03_gp115;old_locus_tag=MPXV-M5312_HM12_Rivers-119 -NC_063383.1 RefSeq CDS 116912 119587 . - 0 ID=cds-YP_010377118.1;Parent=gene-NBT03_gp115;Dbxref=Genbank:YP_010377118.1,GeneID:72551531;Name=YP_010377118.1;Note=A11L%3B similar to Vaccinia virus strain Copenhagen A10L%3B major virion core protein p4a;gbkey=CDS;gene_name=OPG136;locus_tag=NBT03_gp115;product=MPXVgp121;protein_id=YP_010377118.1 -NC_063383.1 RefSeq gene 119602 120558 . + . ID=gene-NBT03_gp116;Dbxref=GeneID:72551532;Name=OPG137;gbkey=Gene;gene_name=OPG137;gene_biotype=protein_coding;locus_tag=NBT03_gp116;old_locus_tag=MPXV-M5312_HM12_Rivers-120 -NC_063383.1 RefSeq CDS 119602 120558 . + 0 ID=cds-YP_010377119.1;Parent=gene-NBT03_gp116;Dbxref=Genbank:YP_010377119.1,GeneID:72551532;Name=YP_010377119.1;Note=A12R%3B similar to Vaccinia virus strain Copenhagen A11R;gbkey=CDS;gene_name=OPG137;locus_tag=NBT03_gp116;product=MPXVgp122;protein_id=YP_010377119.1 -NC_063383.1 RefSeq gene 120560 121132 . - . ID=gene-NBT03_gp117;Dbxref=GeneID:72551533;Name=OPG138;gbkey=Gene;gene_name=OPG138;gene_biotype=protein_coding;locus_tag=NBT03_gp117;old_locus_tag=MPXV-M5312_HM12_Rivers-121 -NC_063383.1 RefSeq CDS 120560 121132 . - 0 ID=cds-YP_010377120.1;Parent=gene-NBT03_gp117;Dbxref=Genbank:YP_010377120.1,GeneID:72551533;Name=YP_010377120.1;Note=A13L%3B similar to Vaccinia virus strain Copenhagen A12L%3B virion core protein;gbkey=CDS;gene_name=OPG138;locus_tag=NBT03_gp117;product=MPXVgp123;protein_id=YP_010377120.1 -NC_063383.1 RefSeq gene 121156 121368 . - . ID=gene-NBT03_gp118;Dbxref=GeneID:72551534;Name=OPG139;gbkey=Gene;gene_name=OPG139;gene_biotype=protein_coding;locus_tag=NBT03_gp118;old_locus_tag=MPXV-M5312_HM12_Rivers-122 -NC_063383.1 RefSeq CDS 121156 121368 . - 0 ID=cds-YP_010377121.1;Parent=gene-NBT03_gp118;Dbxref=Genbank:YP_010377121.1,GeneID:72551534;Name=YP_010377121.1;Note=A14L%3B similar to Vaccinia virus strain Copenhagen A13L%3B IMV inner and outer membrane protein;gbkey=CDS;gene_name=OPG139;locus_tag=NBT03_gp118;product=MPXVgp124;protein_id=YP_010377121.1 -NC_063383.1 RefSeq gene 121474 121746 . - . ID=gene-NBT03_gp119;Dbxref=GeneID:72551535;Name=OPG140;gbkey=Gene;gene_name=OPG140;gene_biotype=protein_coding;locus_tag=NBT03_gp119;old_locus_tag=MPXV-M5312_HM12_Rivers-123 -NC_063383.1 RefSeq CDS 121474 121746 . - 0 ID=cds-YP_010377122.1;Parent=gene-NBT03_gp119;Dbxref=Genbank:YP_010377122.1,GeneID:72551535;Name=YP_010377122.1;Note=A15L%3B similar to Vaccinia virus strain Copenhagen A14L%3B IMV inner membrane protein;gbkey=CDS;gene_name=OPG140;locus_tag=NBT03_gp119;product=MPXVgp125;protein_id=YP_010377122.1 -NC_063383.1 RefSeq gene 121763 121924 . - . ID=gene-NBT03_gp120;Dbxref=GeneID:72551536;Name=OPG141;gbkey=Gene;gene_name=OPG141;gene_biotype=protein_coding;locus_tag=NBT03_gp120;old_locus_tag=MPXV-M5312_HM12_Rivers-124 -NC_063383.1 RefSeq CDS 121763 121924 . - 0 ID=cds-YP_010377123.1;Parent=gene-NBT03_gp120;Dbxref=Genbank:YP_010377123.1,GeneID:72551536;Name=YP_010377123.1;gbkey=CDS;gene_name=OPG141;locus_tag=NBT03_gp120;product=A15.5L;protein_id=YP_010377123.1 -NC_063383.1 RefSeq gene 121914 122198 . - . ID=gene-NBT03_gp121;Dbxref=GeneID:72551537;Name=OPG142;gbkey=Gene;gene_name=OPG142;gene_biotype=protein_coding;locus_tag=NBT03_gp121;old_locus_tag=MPXV-M5312_HM12_Rivers-125 -NC_063383.1 RefSeq CDS 121914 122198 . - 0 ID=cds-YP_010377124.1;Parent=gene-NBT03_gp121;Dbxref=Genbank:YP_010377124.1,GeneID:72551537;Name=YP_010377124.1;Note=A16L%3B similar to Vaccinia virus strain Copenhagen A15L;gbkey=CDS;gene_name=OPG142;locus_tag=NBT03_gp121;product=MPXVgp126;protein_id=YP_010377124.1 -NC_063383.1 RefSeq gene 122182 123315 . - . ID=gene-NBT03_gp122;Dbxref=GeneID:72551538;Name=OPG143;gbkey=Gene;gene_name=OPG143;gene_biotype=protein_coding;locus_tag=NBT03_gp122;old_locus_tag=MPXV-M5312_HM12_Rivers-126 -NC_063383.1 RefSeq CDS 122182 123315 . - 0 ID=cds-YP_010377125.1;Parent=gene-NBT03_gp122;Dbxref=Genbank:YP_010377125.1,GeneID:72551538;Name=YP_010377125.1;Note=A17L%3B similar to Vaccinia virus strain Copenhagen A16L%3B soluble myristylated protein;gbkey=CDS;gene_name=OPG143;locus_tag=NBT03_gp122;product=MPXVgp127;protein_id=YP_010377125.1 -NC_063383.1 RefSeq gene 123318 123932 . - . ID=gene-NBT03_gp123;Dbxref=GeneID:72551539;Name=OPG144;gbkey=Gene;gene_name=OPG144;gene_biotype=protein_coding;locus_tag=NBT03_gp123;old_locus_tag=MPXV-M5312_HM12_Rivers-127 -NC_063383.1 RefSeq CDS 123318 123932 . - 0 ID=cds-YP_010377126.1;Parent=gene-NBT03_gp123;Dbxref=Genbank:YP_010377126.1,GeneID:72551539;Name=YP_010377126.1;Note=A18L%3B similar to Vaccinia virus strain Copenhagen A17L%3B IMV surface membrane protein%3B early function in virion morphgenesis;gbkey=CDS;gene_name=OPG144;locus_tag=NBT03_gp123;product=MPXVgp128;protein_id=YP_010377126.1 -NC_063383.1 RefSeq gene 123947 125425 . + . ID=gene-NBT03_gp124;Dbxref=GeneID:72551540;Name=OPG145;gbkey=Gene;gene_name=OPG145;gene_biotype=protein_coding;locus_tag=NBT03_gp124;old_locus_tag=MPXV-M5312_HM12_Rivers-128 -NC_063383.1 RefSeq CDS 123947 125425 . + 0 ID=cds-YP_010377127.1;Parent=gene-NBT03_gp124;Dbxref=Genbank:YP_010377127.1,GeneID:72551540;Name=YP_010377127.1;Note=A19R%3B similar to Vaccinia virus strain Copenhagen A1 8R%3B virion core associated DNA helicase%3B post-replicative negative transcription elongation factor;gbkey=CDS;gene_name=OPG145;locus_tag=NBT03_gp124;product=MPXVgp129;protein_id=YP_010377127.1 -NC_063383.1 RefSeq gene 125406 125639 . - . ID=gene-NBT03_gp125;Dbxref=GeneID:72551541;Name=OPG146;gbkey=Gene;gene_name=OPG146;gene_biotype=protein_coding;locus_tag=NBT03_gp125;old_locus_tag=MPXV-M5312_HM12_Rivers-129 -NC_063383.1 RefSeq CDS 125406 125639 . - 0 ID=cds-YP_010377128.1;Parent=gene-NBT03_gp125;Dbxref=Genbank:YP_010377128.1,GeneID:72551541;Name=YP_010377128.1;Note=A20L%3B similar to Vaccinia virus strain Copenhagen A19L;gbkey=CDS;gene_name=OPG146;locus_tag=NBT03_gp125;product=MPXVgp130;protein_id=YP_010377128.1 -NC_063383.1 RefSeq gene 125640 125987 . - . ID=gene-NBT03_gp126;Dbxref=GeneID:72551542;Name=OPG147;gbkey=Gene;gene_name=OPG147;gene_biotype=protein_coding;locus_tag=NBT03_gp126;old_locus_tag=MPXV-M5312_HM12_Rivers-130 -NC_063383.1 RefSeq CDS 125640 125987 . - 0 ID=cds-YP_010377129.1;Parent=gene-NBT03_gp126;Dbxref=Genbank:YP_010377129.1,GeneID:72551542;Name=YP_010377129.1;Note=A21L%3B similar to Vaccinia virus strain Copenhagen A21L;gbkey=CDS;gene_name=OPG147;locus_tag=NBT03_gp126;product=MPXVgp131;protein_id=YP_010377129.1 -NC_063383.1 RefSeq gene 125986 127266 . + . ID=gene-NBT03_gp127;Dbxref=GeneID:72551543;Name=OPG148;gbkey=Gene;gene_name=OPG148;gene_biotype=protein_coding;locus_tag=NBT03_gp127;old_locus_tag=MPXV-M5312_HM12_Rivers-131 -NC_063383.1 RefSeq CDS 125986 127266 . + 0 ID=cds-YP_010377130.1;Parent=gene-NBT03_gp127;Dbxref=Genbank:YP_010377130.1,GeneID:72551543;Name=YP_010377130.1;Note=A22R%3B similar to Vaccinia virus strain Copenhagen A20R%3B processivity factor for the viral DNA polymerase%2C VPF;gbkey=CDS;gene_name=OPG148;locus_tag=NBT03_gp127;product=MPXVgp132;protein_id=YP_010377130.1 -NC_063383.1 RefSeq gene 127196 127759 . + . ID=gene-NBT03_gp128;Dbxref=GeneID:72551544;Name=OPG149;gbkey=Gene;gene_name=OPG149;gene_biotype=protein_coding;locus_tag=NBT03_gp128;old_locus_tag=MPXV-M5312_HM12_Rivers-132 -NC_063383.1 RefSeq CDS 127196 127759 . + 0 ID=cds-YP_010377131.1;Parent=gene-NBT03_gp128;Dbxref=Genbank:YP_010377131.1,GeneID:72551544;Name=YP_010377131.1;Note=A23R%3B similar to Vaccinia virus strain Copenhagen A22R;gbkey=CDS;gene_name=OPG149;locus_tag=NBT03_gp128;product=MPXVgp133;protein_id=YP_010377131.1 -NC_063383.1 RefSeq gene 127779 128927 . + . ID=gene-NBT03_gp129;Dbxref=GeneID:72551545;Name=OPG150;gbkey=Gene;gene_name=OPG150;gene_biotype=protein_coding;locus_tag=NBT03_gp129;old_locus_tag=MPXV-M5312_HM12_Rivers-133 -NC_063383.1 RefSeq CDS 127779 128927 . + 0 ID=cds-YP_010377132.1;Parent=gene-NBT03_gp129;Dbxref=Genbank:YP_010377132.1,GeneID:72551545;Name=YP_010377132.1;Note=A24R%3B similar to Vaccinia virus strain Copenhagen A23R%3B intermediate transcription factor%2C VITF-3%2C 45 kDa;gbkey=CDS;gene_name=OPG150;locus_tag=NBT03_gp129;product=MPXVgp134;protein_id=YP_010377132.1 -NC_063383.1 RefSeq gene 128924 132418 . + . ID=gene-NBT03_gp130;Dbxref=GeneID:72551546;Name=OPG151;gbkey=Gene;gene_name=OPG151;gene_biotype=protein_coding;locus_tag=NBT03_gp130;old_locus_tag=MPXV-M5312_HM12_Rivers-134 -NC_063383.1 RefSeq CDS 128924 132418 . + 0 ID=cds-YP_010377133.1;Parent=gene-NBT03_gp130;Dbxref=Genbank:YP_010377133.1,GeneID:72551546;Name=YP_010377133.1;Note=A25R%3B similar to Vaccinia virus strain Copenhagen A24R%3B RNA polymerase%2C 132 kDa subunit;gbkey=CDS;gene_name=OPG151;locus_tag=NBT03_gp130;product=MPXVgp135;protein_id=YP_010377133.1 -NC_063383.1 RefSeq gene 136138 137667 . - . ID=gene-NBT03_gp131;Dbxref=GeneID:72551547;Name=OPG153;gbkey=Gene;gene_name=OPG153;gene_biotype=protein_coding;locus_tag=NBT03_gp131;old_locus_tag=MPXV-M5312_HM12_Rivers-137 -NC_063383.1 RefSeq CDS 136138 137667 . - 0 ID=cds-YP_010377134.1;Parent=gene-NBT03_gp131;Dbxref=Genbank:YP_010377134.1,GeneID:72551547;Name=YP_010377134.1;Note=A28L%3B major component of IMV surface tubules%3B p4c;gbkey=CDS;gene_name=OPG153;locus_tag=NBT03_gp131;product=MPXVgp138;protein_id=YP_010377134.1 -NC_063383.1 RefSeq gene 137718 138050 . - . ID=gene-NBT03_gp132;Dbxref=GeneID:72551548;Name=OPG154;gbkey=Gene;gene_name=OPG154;gene_biotype=protein_coding;locus_tag=NBT03_gp132;old_locus_tag=MPXV-M5312_HM12_Rivers-138 -NC_063383.1 RefSeq CDS 137718 138050 . - 0 ID=cds-YP_010377135.1;Parent=gene-NBT03_gp132;Dbxref=Genbank:YP_010377135.1,GeneID:72551548;Name=YP_010377135.1;Note=A29L%3B similar to Vaccinia virus strain Copenhagen A27L%3B IMV surface membrane 14 kDa fusion protein%3B binding to cell surface heparan;gbkey=CDS;gene_name=OPG154;locus_tag=NBT03_gp132;product=MPXVgp139;protein_id=YP_010377135.1 -NC_063383.1 RefSeq gene 138051 138491 . - . ID=gene-NBT03_gp133;Dbxref=GeneID:72551549;Name=OPG155;gbkey=Gene;gene_name=OPG155;gene_biotype=protein_coding;locus_tag=NBT03_gp133;old_locus_tag=MPXV-M5312_HM12_Rivers-139 -NC_063383.1 RefSeq CDS 138051 138491 . - 0 ID=cds-YP_010377136.1;Parent=gene-NBT03_gp133;Dbxref=Genbank:YP_010377136.1,GeneID:72551549;Name=YP_010377136.1;Note=A30L%3B similar to Vaccinia virus strain Copenhagen A28L;gbkey=CDS;gene_name=OPG155;locus_tag=NBT03_gp133;product=MPXVgp140;protein_id=YP_010377136.1 -NC_063383.1 RefSeq gene 138492 139409 . - . ID=gene-NBT03_gp134;Dbxref=GeneID:72551550;Name=OPG156;gbkey=Gene;gene_name=OPG156;gene_biotype=protein_coding;locus_tag=NBT03_gp134;old_locus_tag=MPXV-M5312_HM12_Rivers-140 -NC_063383.1 RefSeq CDS 138492 139409 . - 0 ID=cds-YP_010377137.1;Parent=gene-NBT03_gp134;Dbxref=Genbank:YP_010377137.1,GeneID:72551550;Name=YP_010377137.1;Note=A31L%3B similar to Vaccinia virus strain Copenhagen A29L%3B RNA polymerase%2C 35 kDa subunit;gbkey=CDS;gene_name=OPG156;locus_tag=NBT03_gp134;product=MPXVgp141;protein_id=YP_010377137.1 -NC_063383.1 RefSeq gene 139372 139608 . - . ID=gene-NBT03_gp135;Dbxref=GeneID:72551551;Name=OPG157;gbkey=Gene;gene_name=OPG157;gene_biotype=protein_coding;locus_tag=NBT03_gp135;old_locus_tag=MPXV-M5312_HM12_Rivers-141 -NC_063383.1 RefSeq CDS 139372 139608 . - 0 ID=cds-YP_010377138.1;Parent=gene-NBT03_gp135;Dbxref=Genbank:YP_010377138.1,GeneID:72551551;Name=YP_010377138.1;Note=A32L%3B similar to Vaccinia virus strain Copenhagen A30L;gbkey=CDS;gene_name=OPG157;locus_tag=NBT03_gp135;product=MPXVgp142;protein_id=YP_010377138.1 -NC_063383.1 RefSeq gene 139641 139769 . - . ID=gene-NBT03_gp136;Dbxref=GeneID:72551552;Name=OPG158;gbkey=Gene;gene_name=OPG158;gene_biotype=protein_coding;locus_tag=NBT03_gp136;old_locus_tag=MPXV-M5312_HM12_Rivers-142 -NC_063383.1 RefSeq CDS 139641 139769 . - 0 ID=cds-YP_010377139.1;Parent=gene-NBT03_gp136;Dbxref=Genbank:YP_010377139.1,GeneID:72551552;Name=YP_010377139.1;gbkey=CDS;gene_name=OPG158;locus_tag=NBT03_gp136;product=A32.5L;protein_id=YP_010377139.1 -NC_063383.1 RefSeq gene 139768 140205 . + . ID=gene-NBT03_gp137;Dbxref=GeneID:72551553;Name=OPG159;gbkey=Gene;gene_name=OPG159;gene_biotype=protein_coding;locus_tag=NBT03_gp137;old_locus_tag=MPXV-M5312_HM12_Rivers-143 -NC_063383.1 RefSeq CDS 139768 140205 . + 0 ID=cds-YP_010377140.1;Parent=gene-NBT03_gp137;Dbxref=Genbank:YP_010377140.1,GeneID:72551553;Name=YP_010377140.1;Note=A33R%3B similar to Vaccinia virus strain Copenhagen A31R;gbkey=CDS;gene_name=OPG159;locus_tag=NBT03_gp137;product=MPXVgp143;protein_id=YP_010377140.1 -NC_063383.1 RefSeq gene 140172 141074 . - . ID=gene-NBT03_gp138;Dbxref=GeneID:72551554;Name=OPG160;gbkey=Gene;gene_name=OPG160;gene_biotype=protein_coding;locus_tag=NBT03_gp138;old_locus_tag=MPXV-M5312_HM12_Rivers-144 -NC_063383.1 RefSeq CDS 140172 141074 . - 0 ID=cds-YP_010377141.1;Parent=gene-NBT03_gp138;Dbxref=Genbank:YP_010377141.1,GeneID:72551554;Name=YP_010377141.1;Note=A34L%3B similar to Vaccinia virus strain Copenhagen A32L%3B DNA packaging into virion%3B NTP-binding motif A;gbkey=CDS;gene_name=OPG160;locus_tag=NBT03_gp138;product=MPXVgp144;protein_id=YP_010377141.1 -NC_063383.1 RefSeq gene 141102 141647 . + . ID=gene-NBT03_gp139;Dbxref=GeneID:72551555;Name=OPG161;gbkey=Gene;gene_name=OPG161;gene_biotype=protein_coding;locus_tag=NBT03_gp139;old_locus_tag=MPXV-M5312_HM12_Rivers-145 -NC_063383.1 RefSeq CDS 141102 141647 . + 0 ID=cds-YP_010377142.1;Parent=gene-NBT03_gp139;Dbxref=Genbank:YP_010377142.1,GeneID:72551555;Name=YP_010377142.1;Note=A35R%3B similar to Vaccinia virus strain Copenhagen A33R%3B EEV envelope glycoprotein%2C needed for formation of actin-containing microvilli and cell-to-cell spread of virion%3B interacts with VAC A36R;gbkey=CDS;gene_name=OPG161;locus_tag=NBT03_gp139;product=MPXVgp145;protein_id=YP_010377142.1 -NC_063383.1 RefSeq gene 141652 142158 . + . ID=gene-NBT03_gp140;Dbxref=GeneID:72551556;Name=OPG162;gbkey=Gene;gene_name=OPG162;gene_biotype=protein_coding;locus_tag=NBT03_gp140;old_locus_tag=MPXV-M5312_HM12_Rivers-146 -NC_063383.1 RefSeq CDS 141652 142158 . + 0 ID=cds-YP_010377143.1;Parent=gene-NBT03_gp140;Dbxref=Genbank:YP_010377143.1,GeneID:72551556;Name=YP_010377143.1;Note=A36R%3B similar to Vaccinia virus strain Copenhagen A3 4R%3B EEV envelope glycoprotein%2C lectin-like%3B required for infectivity of EEV%2C formation of actin-containing microvilli%2C and cell-to-cell spread of virion;gbkey=CDS;gene_name=OPG162;locus_tag=NBT03_gp140;product=MPXVgp146;protein_id=YP_010377143.1 -NC_063383.1 RefSeq gene 142202 142732 . + . ID=gene-NBT03_gp141;Dbxref=GeneID:72551557;Name=OPG163;gbkey=Gene;gene_name=OPG163;gene_biotype=protein_coding;locus_tag=NBT03_gp141;old_locus_tag=MPXV-M5312_HM12_Rivers-147 -NC_063383.1 RefSeq CDS 142202 142732 . + 0 ID=cds-YP_010377144.1;Parent=gene-NBT03_gp141;Dbxref=Genbank:YP_010377144.1,GeneID:72551557;Name=YP_010377144.1;Note=A37R%3B similar to Vaccinia virus strain Copenhagen A35R;gbkey=CDS;gene_name=OPG163;locus_tag=NBT03_gp141;product=MPXVgp147;protein_id=YP_010377144.1 -NC_063383.1 RefSeq gene 142778 143464 . + . ID=gene-NBT03_gp142;Dbxref=GeneID:72551558;Name=OPG164;gbkey=Gene;gene_name=OPG164;gene_biotype=protein_coding;locus_tag=NBT03_gp142;old_locus_tag=MPXV-M5312_HM12_Rivers-148 -NC_063383.1 RefSeq CDS 142778 143464 . + 0 ID=cds-YP_010377145.1;Parent=gene-NBT03_gp142;Dbxref=Genbank:YP_010377145.1,GeneID:72551558;Name=YP_010377145.1;Note=A38R%3B similar to Vaccinia virus strain Copenhagen A36R%3B IEV but not CEV envelope protein%3B plays critical role for actin tail formation%3B interacts with VAC A33R and A34R;gbkey=CDS;gene_name=OPG164;locus_tag=NBT03_gp142;product=MPXVgp148;protein_id=YP_010377145.1 -NC_063383.1 RefSeq gene 143516 144322 . + . ID=gene-NBT03_gp143;Dbxref=GeneID:72551559;Name=OPG165;gbkey=Gene;gene_name=OPG165;gene_biotype=protein_coding;locus_tag=NBT03_gp143;old_locus_tag=MPXV-M5312_HM12_Rivers-149 -NC_063383.1 RefSeq CDS 143516 144322 . + 0 ID=cds-YP_010377146.1;Parent=gene-NBT03_gp143;Dbxref=Genbank:YP_010377146.1,GeneID:72551559;Name=YP_010377146.1;Note=A39R%3B similar to Vaccinia virus strain Copenhagen A37R;gbkey=CDS;gene_name=OPG165;locus_tag=NBT03_gp143;product=MPXVgp149;protein_id=YP_010377146.1 -NC_063383.1 RefSeq gene 144574 145407 . - . ID=gene-NBT03_gp144;Dbxref=GeneID:72551560;Name=OPG167;gbkey=Gene;gene_name=OPG167;gene_biotype=protein_coding;locus_tag=NBT03_gp144;old_locus_tag=MPXV-M5312_HM12_Rivers-150 -NC_063383.1 RefSeq CDS 144574 145407 . - 0 ID=cds-YP_010377147.1;Parent=gene-NBT03_gp144;Dbxref=Genbank:YP_010377147.1,GeneID:72551560;Name=YP_010377147.1;Note=A40L%3B similar to Vaccinia virus strain Copenhagen A38L%3B integral membrane glycoprotein%3B immunoglobulin-like%3B regulation of the influx of extracellular Ca2+;gbkey=CDS;gene_name=OPG167;locus_tag=NBT03_gp144;product=MPXVgp150;protein_id=YP_010377147.1 -NC_063383.1 RefSeq gene 146113 146778 . - . ID=gene-NBT03_gp145;Dbxref=GeneID:72551561;Name=OPG170;gbkey=Gene;gene_name=OPG170;gene_biotype=protein_coding;locus_tag=NBT03_gp145;old_locus_tag=MPXV-M5312_HM12_Rivers-151 -NC_063383.1 RefSeq CDS 146113 146778 . - 0 ID=cds-YP_010377148.1;Parent=gene-NBT03_gp145;Dbxref=Genbank:YP_010377148.1,GeneID:72551561;Name=YP_010377148.1;Note=A41L%3B similar to Vaccinia virus strain Copenhagen A41L%3B secreted protein reducing infiltration of inflammatory cells into the infected area;gbkey=CDS;gene_name=OPG170;locus_tag=NBT03_gp145;product=MPXVgp151;protein_id=YP_010377148.1 -NC_063383.1 RefSeq gene 146988 147389 . + . ID=gene-NBT03_gp146;Dbxref=GeneID:72551562;Name=OPG171;gbkey=Gene;gene_name=OPG171;gene_biotype=protein_coding;locus_tag=NBT03_gp146;old_locus_tag=MPXV-M5312_HM12_Rivers-152 -NC_063383.1 RefSeq CDS 146988 147389 . + 0 ID=cds-YP_010377149.1;Parent=gene-NBT03_gp146;Dbxref=Genbank:YP_010377149.1,GeneID:72551562;Name=YP_010377149.1;Note=A42R%3B similar to Vaccinia virus strain Copenhagen A42R%3B profilin-like;gbkey=CDS;gene_name=OPG171;locus_tag=NBT03_gp146;product=MPXVgp152;protein_id=YP_010377149.1 -NC_063383.1 RefSeq gene 147427 148017 . + . ID=gene-NBT03_gp147;Dbxref=GeneID:72551563;Name=OPG172;gbkey=Gene;gene_name=OPG172;gene_biotype=protein_coding;locus_tag=NBT03_gp147;old_locus_tag=MPXV-M5312_HM12_Rivers-153 -NC_063383.1 RefSeq CDS 147427 148017 . + 0 ID=cds-YP_010377150.1;Parent=gene-NBT03_gp147;Dbxref=Genbank:YP_010377150.1,GeneID:72551563;Name=YP_010377150.1;Note=A43R%3B similar to Vaccinia virus strain Copenhagen A43R%3B membrane glycoprotein;gbkey=CDS;gene_name=OPG172;locus_tag=NBT03_gp147;product=MPXVgp153;protein_id=YP_010377150.1 -NC_063383.1 RefSeq gene 148037 148261 . + . ID=gene-NBT03_gp148;Dbxref=GeneID:72551564;Name=OPG173;gbkey=Gene;gene_name=OPG173;gene_biotype=protein_coding;locus_tag=NBT03_gp148;old_locus_tag=MPXV-M5312_HM12_Rivers-154 -NC_063383.1 RefSeq CDS 148037 148261 . + 0 ID=cds-YP_010377151.1;Parent=gene-NBT03_gp148;Dbxref=Genbank:YP_010377151.1,GeneID:72551564;Name=YP_010377151.1;Note=A44R;gbkey=CDS;gene_name=OPG173;locus_tag=NBT03_gp148;product=MPXVgp154;protein_id=YP_010377151.1 -NC_063383.1 RefSeq gene 148355 149395 . - . ID=gene-NBT03_gp149;Dbxref=GeneID:72551565;Name=OPG174;gbkey=Gene;gene_name=OPG174;gene_biotype=protein_coding;locus_tag=NBT03_gp149;old_locus_tag=MPXV-M5312_HM12_Rivers-155 -NC_063383.1 RefSeq CDS 148355 149395 . - 0 ID=cds-YP_010377152.1;Parent=gene-NBT03_gp149;Dbxref=Genbank:YP_010377152.1,GeneID:72551565;Name=YP_010377152.1;Note=A45L%3B similar to Vaccinia virus strain Copenhagen A44L%3B 3-b-Hydroxy-delta5-steroid dehydrogenase;gbkey=CDS;gene_name=OPG174;locus_tag=NBT03_gp149;product=MPXVgp158;protein_id=YP_010377152.1 -NC_063383.1 RefSeq gene 149442 149819 . + . ID=gene-NBT03_gp150;Dbxref=GeneID:72551566;Name=OPG175;gbkey=Gene;gene_name=OPG175;gene_biotype=protein_coding;locus_tag=NBT03_gp150;old_locus_tag=MPXV-M5312_HM12_Rivers-156 -NC_063383.1 RefSeq CDS 149442 149819 . + 0 ID=cds-YP_010377153.1;Parent=gene-NBT03_gp150;Dbxref=Genbank:YP_010377153.1,GeneID:72551566;Name=YP_010377153.1;Note=A46R%3B similar to Vaccinia virus strain Copenhagen A45R%3B superoxide dismutase-like%3B virion core protein;gbkey=CDS;gene_name=OPG175;locus_tag=NBT03_gp150;product=MPXVgp156;protein_id=YP_010377153.1 -NC_063383.1 RefSeq gene 149809 150531 . + . ID=gene-NBT03_gp151;Dbxref=GeneID:72551567;Name=OPG176;gbkey=Gene;gene_name=OPG176;gene_biotype=protein_coding;locus_tag=NBT03_gp151;old_locus_tag=MPXV-M5312_HM12_Rivers-157 -NC_063383.1 RefSeq CDS 149809 150531 . + 0 ID=cds-YP_010377154.1;Parent=gene-NBT03_gp151;Dbxref=Genbank:YP_010377154.1,GeneID:72551567;Name=YP_010377154.1;Note=A47R%3B similar to Vaccinia virus strain Copenhagen A46R;gbkey=CDS;gene_name=OPG176;locus_tag=NBT03_gp151;product=MPXVgp157;protein_id=YP_010377154.1 -NC_063383.1 RefSeq gene 151509 152123 . + . ID=gene-NBT03_gp152;Dbxref=GeneID:72551568;Name=OPG178;gbkey=Gene;gene_name=OPG178;gene_biotype=protein_coding;locus_tag=NBT03_gp152;old_locus_tag=MPXV-M5312_HM12_Rivers-158 -NC_063383.1 RefSeq CDS 151509 152123 . + 0 ID=cds-YP_010377155.1;Parent=gene-NBT03_gp152;Dbxref=Genbank:YP_010377155.1,GeneID:72551568;Name=YP_010377155.1;Note=A49R%3B similar to Vaccinia virus strain Copenhagen A48R%3B thymidylate kinase;gbkey=CDS;gene_name=OPG178;locus_tag=NBT03_gp152;product=MPXVgp159;protein_id=YP_010377155.1 -NC_063383.1 RefSeq gene 152692 154371 . + . ID=gene-NBT03_gp153;Dbxref=GeneID:72551569;Name=OPG180;gbkey=Gene;gene_name=OPG180;gene_biotype=protein_coding;locus_tag=NBT03_gp153;old_locus_tag=MPXV-M5312_HM12_Rivers-159 -NC_063383.1 RefSeq CDS 152692 154371 . + 0 ID=cds-YP_010377156.1;Parent=gene-NBT03_gp153;Dbxref=Genbank:YP_010377156.1,GeneID:72551569;Name=YP_010377156.1;Note=A50R%3B similar to Vaccinia virus strain Copenhagen A50R%3B DNA ligase;gbkey=CDS;gene_name=OPG180;locus_tag=NBT03_gp153;product=MPXVgp160;protein_id=YP_010377156.1 -NC_063383.1 RefSeq gene 154412 155416 . + . ID=gene-NBT03_gp154;Dbxref=GeneID:72551570;Name=OPG181;gbkey=Gene;gene_name=OPG181;gene_biotype=protein_coding;locus_tag=NBT03_gp154;old_locus_tag=MPXV-M5312_HM12_Rivers-160 -NC_063383.1 RefSeq CDS 154412 155416 . + 0 ID=cds-YP_010377157.1;Parent=gene-NBT03_gp154;Dbxref=Genbank:YP_010377157.1,GeneID:72551570;Name=YP_010377157.1;Note=A51R%3B similar to Vaccinia virus strain Copenhagen A51R;gbkey=CDS;gene_name=OPG181;locus_tag=NBT03_gp154;product=MPXVgp161;protein_id=YP_010377157.1 -NC_063383.1 RefSeq gene 158917 159858 . + . ID=gene-NBT03_gp155;Dbxref=GeneID:72551571;Name=OPG185;gbkey=Gene;gene_name=OPG185;gene_biotype=protein_coding;locus_tag=NBT03_gp155;old_locus_tag=MPXV-M5312_HM12_Rivers-162 -NC_063383.1 RefSeq CDS 158917 159858 . + 0 ID=cds-YP_010377158.1;Parent=gene-NBT03_gp155;Dbxref=Genbank:YP_010377158.1,GeneID:72551571;Name=YP_010377158.1;Note=B2R%3B similar to Vaccinia virus strain Copenhagen A56R%3B EEV envelope and cell membrane glycoprotein hemagglutinin%3B inhibition of the ability of infected cells to fuse%3B interacts with VAC F13L;gbkey=CDS;gene_name=OPG185;locus_tag=NBT03_gp155;product=MPXVgp163;protein_id=YP_010377158.1 -NC_063383.1 RefSeq gene 160622 161533 . + . ID=gene-NBT03_gp156;Dbxref=GeneID:72551572;Name=OPG187;gbkey=Gene;gene_name=OPG187;gene_biotype=protein_coding;locus_tag=NBT03_gp156;old_locus_tag=MPXV-M5312_HM12_Rivers-163 -NC_063383.1 RefSeq CDS 160622 161533 . + 0 ID=cds-YP_010377159.1;Parent=gene-NBT03_gp156;Dbxref=Genbank:YP_010377159.1,GeneID:72551572;Name=YP_010377159.1;Note=B3R%3B similar to Vaccinia virus strain Copenhagen B1R%3B serine;gbkey=CDS;gene_name=OPG187;locus_tag=NBT03_gp156;product=MPXVgp164;protein_id=YP_010377159.1 -NC_063383.1 RefSeq gene 161596 163107 . + . ID=gene-NBT03_gp157;Dbxref=GeneID:72551573;Name=OPG188;gbkey=Gene;gene_name=OPG188;gene_biotype=protein_coding;locus_tag=NBT03_gp157;old_locus_tag=MPXV-M5312_HM12_Rivers-164 -NC_063383.1 RefSeq CDS 161596 163107 . + 0 ID=cds-YP_010377160.1;Parent=gene-NBT03_gp157;Dbxref=Genbank:YP_010377160.1,GeneID:72551573;Name=YP_010377160.1;Note=B4R%3B schlafen-like;gbkey=CDS;gene_name=OPG188;locus_tag=NBT03_gp157;product=MPXVgp165;protein_id=YP_010377160.1 -NC_063383.1 RefSeq gene 163333 165018 . + . ID=gene-NBT03_gp158;Dbxref=GeneID:72551574;Name=OPG189;gbkey=Gene;gene_name=OPG189;gene_biotype=protein_coding;locus_tag=NBT03_gp158;old_locus_tag=MPXV-M5312_HM12_Rivers-165 -NC_063383.1 RefSeq CDS 163333 165018 . + 0 ID=cds-YP_010377161.1;Parent=gene-NBT03_gp158;Dbxref=Genbank:YP_010377161.1,GeneID:72551574;Name=YP_010377161.1;Note=B5R%3B similar to Vaccinia virus strain Copenhagen B4R%3B ankyrin-like;gbkey=CDS;gene_name=OPG189;locus_tag=NBT03_gp158;product=MPXVgp166;protein_id=YP_010377161.1 -NC_063383.1 RefSeq gene 165122 166075 . + . ID=gene-NBT03_gp159;Dbxref=GeneID:72551575;Name=OPG190;gbkey=Gene;gene_name=OPG190;gene_biotype=protein_coding;locus_tag=NBT03_gp159;old_locus_tag=MPXV-M5312_HM12_Rivers-166 -NC_063383.1 RefSeq CDS 165122 166075 . + 0 ID=cds-YP_010377162.1;Parent=gene-NBT03_gp159;Dbxref=Genbank:YP_010377162.1,GeneID:72551575;Name=YP_010377162.1;Note=B6R%3B similar to Vaccinia virus strain Copenhagen B5R%3B palmitated 42 kDa glycoprotein located both on the membranes of infected cells and on EEV envelope%3B complement control protein-like;gbkey=CDS;gene_name=OPG190;locus_tag=NBT03_gp159;product=MPXVgp167;protein_id=YP_010377162.1 -NC_063383.1 RefSeq gene 166161 166667 . + . ID=gene-NBT03_gp160;Dbxref=GeneID:72551576;Name=OPG191;gbkey=Gene;gene_name=OPG191;gene_biotype=protein_coding;locus_tag=NBT03_gp160;old_locus_tag=MPXV-M5312_HM12_Rivers-167 -NC_063383.1 RefSeq CDS 166161 166667 . + 0 ID=cds-YP_010377163.1;Parent=gene-NBT03_gp160;Dbxref=Genbank:YP_010377163.1,GeneID:72551576;Name=YP_010377163.1;Note=B7R%3B similar to Vaccinia virus strain Copenhagen B6R;gbkey=CDS;gene_name=OPG191;locus_tag=NBT03_gp160;product=MPXVgp168;protein_id=YP_010377163.1 -NC_063383.1 RefSeq gene 166731 167279 . + . ID=gene-NBT03_gp161;Dbxref=GeneID:72551577;Name=OPG192;gbkey=Gene;gene_name=OPG192;gene_biotype=protein_coding;locus_tag=NBT03_gp161;old_locus_tag=MPXV-M5312_HM12_Rivers-168 -NC_063383.1 RefSeq CDS 166731 167279 . + 0 ID=cds-YP_010377164.1;Parent=gene-NBT03_gp161;Dbxref=Genbank:YP_010377164.1,GeneID:72551577;Name=YP_010377164.1;Note=B8R%3B similar to Vaccinia virus strain Copenhagen B7R;gbkey=CDS;gene_name=OPG192;locus_tag=NBT03_gp161;product=MPXVgp169;protein_id=YP_010377164.1 -NC_063383.1 RefSeq gene 167334 168137 . + . ID=gene-NBT03_gp162;Dbxref=GeneID:72551578;Name=OPG193;gbkey=Gene;gene_name=OPG193;gene_biotype=protein_coding;locus_tag=NBT03_gp162;old_locus_tag=MPXV-M5312_HM12_Rivers-169 -NC_063383.1 RefSeq CDS 167334 168137 . + 0 ID=cds-YP_010377165.1;Parent=gene-NBT03_gp162;Dbxref=Genbank:YP_010377165.1,GeneID:72551578;Name=YP_010377165.1;Note=B9R%3B similar to Vaccinia virus strain Copenhagen B8R%3B secreted IFN-g binding protein;gbkey=CDS;gene_name=OPG193;locus_tag=NBT03_gp162;product=MPXVgp170;protein_id=YP_010377165.1 -NC_063383.1 RefSeq gene 168230 168895 . + . ID=gene-NBT03_gp163;Dbxref=GeneID:72551579;Name=OPG195;gbkey=Gene;gene_name=OPG195;gene_biotype=protein_coding;locus_tag=NBT03_gp163;old_locus_tag=MPXV-M5312_HM12_Rivers-170 -NC_063383.1 RefSeq CDS 168230 168895 . + 0 ID=cds-YP_010377166.1;Parent=gene-NBT03_gp163;Dbxref=Genbank:YP_010377166.1,GeneID:72551579;Name=YP_010377166.1;Note=B10R%3B shope fibroma virus T4 protein-like;gbkey=CDS;gene_name=OPG195;locus_tag=NBT03_gp163;product=MPXVgp171;protein_id=YP_010377166.1 -NC_063383.1 RefSeq gene 169670 169972 . + . ID=gene-NBT03_gp164;Dbxref=GeneID:72551580;Name=OPG197;gbkey=Gene;gene_name=OPG197;gene_biotype=protein_coding;locus_tag=NBT03_gp164;old_locus_tag=MPXV-M5312_HM12_Rivers-171 -NC_063383.1 RefSeq CDS 169670 169972 . + 0 ID=cds-YP_010377167.1;Parent=gene-NBT03_gp164;Dbxref=Genbank:YP_010377167.1,GeneID:72551580;Name=YP_010377167.1;gbkey=CDS;gene_name=OPG197;locus_tag=NBT03_gp164;product=Hypothetical protein (Cop-B11R);protein_id=YP_010377167.1 -NC_063383.1 RefSeq gene 170038 170886 . + . ID=gene-NBT03_gp165;Dbxref=GeneID:72551581;Name=OPG198;gbkey=Gene;gene_name=OPG198;gene_biotype=protein_coding;locus_tag=NBT03_gp165;old_locus_tag=MPXV-M5312_HM12_Rivers-172 -NC_063383.1 RefSeq CDS 170038 170886 . + 0 ID=cds-YP_010377168.1;Parent=gene-NBT03_gp165;Dbxref=Genbank:YP_010377168.1,GeneID:72551581;Name=YP_010377168.1;Note=B11R%3B similar to Vaccinia virus strain Copenhagen B12R%3B protein kinase-like;gbkey=CDS;gene_name=OPG198;locus_tag=NBT03_gp165;product=MPXVgp172;protein_id=YP_010377168.1 -NC_063383.1 RefSeq gene 170988 172022 . + . ID=gene-NBT03_gp166;Dbxref=GeneID:72551582;Name=OPG199;gbkey=Gene;gene_name=OPG199;gene_biotype=protein_coding;locus_tag=NBT03_gp166;old_locus_tag=MPXV-M5312_HM12_Rivers-173 -NC_063383.1 RefSeq CDS 170988 172022 . + 0 ID=cds-YP_010377169.1;Parent=gene-NBT03_gp166;Dbxref=Genbank:YP_010377169.1,GeneID:72551582;Name=YP_010377169.1;Note=SPI-2%3B B12R%3B serine protease inhibitor-like%2C SPI-2%3B inhibition of the IL-1b converting enzyme%3B apoptosis inhibition;gbkey=CDS;gene_name=OPG199;locus_tag=NBT03_gp166;product=MPXVgp173;protein_id=YP_010377169.1 -NC_063383.1 RefSeq gene 172150 172599 . + . ID=gene-NBT03_gp167;Dbxref=GeneID:72551583;Name=OPG200;gbkey=Gene;gene_name=OPG200;gene_biotype=protein_coding;locus_tag=NBT03_gp167;old_locus_tag=MPXV-M5312_HM12_Rivers-174 -NC_063383.1 RefSeq CDS 172150 172599 . + 0 ID=cds-YP_010377170.1;Parent=gene-NBT03_gp167;Dbxref=Genbank:YP_010377170.1,GeneID:72551583;Name=YP_010377170.1;Note=B13R%3B similar to Vaccinia virus strain Copenhagen B15R;gbkey=CDS;gene_name=OPG200;locus_tag=NBT03_gp167;product=MPXVgp174;protein_id=YP_010377170.1 -NC_063383.1 RefSeq gene 174532 175587 . + . ID=gene-NBT03_gp168;Dbxref=GeneID:72551584;Name=OPG204;gbkey=Gene;gene_name=OPG204;gene_biotype=protein_coding;locus_tag=NBT03_gp168;old_locus_tag=MPXV-M5312_HM12_Rivers-177 -NC_063383.1 RefSeq CDS 174532 175587 . + 0 ID=cds-YP_010377172.1;Parent=gene-NBT03_gp168;Dbxref=Genbank:YP_010377172.1,GeneID:72551584;Name=YP_010377172.1;Note=B16R%3B similar to Vaccinia virus strain Copenhagen B19R%3B cell surface antigen and secreted IFN-a;gbkey=CDS;gene_name=OPG204;locus_tag=NBT03_gp168;product=MPXVgp177;protein_id=YP_010377172.1 -NC_063383.1 RefSeq gene 175656 178019 . + . ID=gene-NBT03_gp169;Dbxref=GeneID:72551585;Name=OPG205;gbkey=Gene;gene_name=OPG205;gene_biotype=protein_coding;locus_tag=NBT03_gp169;old_locus_tag=MPXV-M5312_HM12_Rivers-178 -NC_063383.1 RefSeq CDS 175656 178019 . + 0 ID=cds-YP_010377173.1;Parent=gene-NBT03_gp169;Dbxref=Genbank:YP_010377173.1,GeneID:72551585;Name=YP_010377173.1;Note=B17R%3B ankyrin-like;gbkey=CDS;gene_name=OPG205;locus_tag=NBT03_gp169;product=MPXVgp178;protein_id=YP_010377173.1 -NC_063383.1 RefSeq gene 179266 180339 . + . ID=gene-NBT03_gp170;Dbxref=GeneID:72551586;Name=OPG208;gbkey=Gene;gene_name=OPG208;gene_biotype=protein_coding;locus_tag=NBT03_gp170;old_locus_tag=MPXV-M5312_HM12_Rivers-180 -NC_063383.1 RefSeq CDS 179266 180339 . + 0 ID=cds-YP_010377174.1;Parent=gene-NBT03_gp170;Dbxref=Genbank:YP_010377174.1,GeneID:72551586;Name=YP_010377174.1;Note=SPI-1%3B B19R%3B serine protease inhibitor-like%2C SPI-1%3B apoptosis inhibition;gbkey=CDS;gene_name=OPG208;locus_tag=NBT03_gp170;product=MPXVgp180;protein_id=YP_010377174.1 -NC_063383.1 RefSeq gene 180518 181090 . + . ID=gene-NBT03_gp171;Dbxref=GeneID:72551587;Name=OPG209;gbkey=Gene;gene_name=OPG209;gene_biotype=protein_coding;locus_tag=NBT03_gp171;old_locus_tag=MPXV-M5312_HM12_Rivers-181 -NC_063383.1 RefSeq CDS 180518 181090 . + 0 ID=cds-YP_010377175.1;Parent=gene-NBT03_gp171;Dbxref=Genbank:YP_010377175.1,GeneID:72551587;Name=YP_010377175.1;Note=B20R;gbkey=CDS;gene_name=OPG209;locus_tag=NBT03_gp171;product=MPXVgp181;protein_id=YP_010377175.1 -NC_063383.1 RefSeq gene 181356 186998 . + . ID=gene-NBT03_gp172;Dbxref=GeneID:72551588;Name=OPG210;gbkey=Gene;gene_name=OPG210;gene_biotype=protein_coding;locus_tag=NBT03_gp172;old_locus_tag=MPXV-M5312_HM12_Rivers-182 -NC_063383.1 RefSeq CDS 181356 186998 . + 0 ID=cds-YP_010377176.1;Parent=gene-NBT03_gp172;Dbxref=Genbank:YP_010377176.1,GeneID:72551588;Name=YP_010377176.1;Note=B21R%3B putative membrane-associated glycoprotein%3B cadherin-like domain;gbkey=CDS;gene_name=OPG210;locus_tag=NBT03_gp172;product=MPXVgp182;protein_id=YP_010377176.1 -NC_063383.1 RefSeq gene 189199 189660 . + . ID=gene-NBT03_gp173;Dbxref=GeneID:72551589;Name=OPG005;gbkey=Gene;gene_name=OPG005;gene_biotype=protein_coding;locus_tag=NBT03_gp173;old_locus_tag=MPXV-M5312_HM12_Rivers-184 -NC_063383.1 RefSeq CDS 189199 189660 . + 0 ID=cds-YP_010377177.1;Parent=gene-NBT03_gp173;Dbxref=Genbank:YP_010377177.1,GeneID:72551589;Name=YP_010377177.1;Note=N1R%3B similar to Vaccinia virus strain Copenhagen B22R%3B VAC B15R-like;gbkey=CDS;gene_name=OPG005;locus_tag=NBT03_gp173;product=MPXVgp185;protein_id=YP_010377177.1 -NC_063383.1 RefSeq gene 190410 190940 . + . ID=gene-NBT03_gp174;Dbxref=GeneID:72551590;Name=NBT03_gp174;gbkey=Gene;gene_biotype=protein_coding;locus_tag=NBT03_gp174;old_locus_tag=MPXV-M5312_HM12_Rivers-186 -NC_063383.1 RefSeq CDS 190410 190940 . + 0 ID=cds-YP_010377184.1;Parent=gene-NBT03_gp174;Dbxref=Genbank:YP_010377184.1,GeneID:72551590;Name=YP_010377184.1;gbkey=CDS;locus_tag=NBT03_gp174;product=hypothetical protein;protein_id=YP_010377184.1 -NC_063383.1 RefSeq gene 191054 192367 . + . ID=gene-NBT03_gp175;Dbxref=GeneID:72551591;Name=NBT03_gp175;gbkey=Gene;gene_biotype=protein_coding;locus_tag=NBT03_gp175;old_locus_tag=MPXV-M5312_HM12_Rivers-187 -NC_063383.1 RefSeq CDS 191054 192367 . + 0 ID=cds-YP_010377179.1;Parent=gene-NBT03_gp175;Dbxref=Genbank:YP_010377179.1,GeneID:72551591;Name=YP_010377179.1;Note=N4R%3B ankyrin-like;gbkey=CDS;locus_tag=NBT03_gp175;product=MPXVgp188;protein_id=YP_010377179.1 -NC_063383.1 RefSeq gene 192603 194369 . + . ID=gene-NBT03_gp176;Dbxref=GeneID:72551592;Name=OPG003;gbkey=Gene;gene_name=OPG003;gene_biotype=protein_coding;locus_tag=NBT03_gp176;old_locus_tag=MPXV-M5312_HM12_Rivers-188 -NC_063383.1 RefSeq CDS 192603 194369 . + 0 ID=cds-YP_010377180.1;Parent=gene-NBT03_gp176;Dbxref=Genbank:YP_010377180.1,GeneID:72551592;Name=YP_010377180.1;Note=J1R%3B ankyrin-like;gbkey=CDS;gene_name=OPG003;locus_tag=NBT03_gp176;product=MPXVgp189;protein_id=YP_010377180.1 -NC_063383.1 RefSeq gene 194459 195508 . + . ID=gene-NBT03_gp177;Dbxref=GeneID:72551593;Name=OPG002;gbkey=Gene;gene_name=OPG002;gene_biotype=protein_coding;locus_tag=NBT03_gp177;old_locus_tag=MPXV-M5312_HM12_Rivers-189 -NC_063383.1 RefSeq CDS 194459 195508 . + 0 ID=cds-YP_010377181.1;Parent=gene-NBT03_gp177;Dbxref=Genbank:YP_010377181.1,GeneID:72551593;Name=YP_010377181.1;Note=J2R%3B secreted TNF binding protein;gbkey=CDS;gene_name=OPG002;locus_tag=NBT03_gp177;product=MPXVgp190;protein_id=YP_010377181.1 -NC_063383.1 RefSeq gene 195635 196375 . + . ID=gene-NBT03_gp178;Dbxref=GeneID:72551594;Name=OPG001;gbkey=Gene;gene_name=OPG001;gene_biotype=protein_coding;locus_tag=NBT03_gp178;old_locus_tag=MPXV-M5312_HM12_Rivers-190 -NC_063383.1 RefSeq CDS 195635 196375 . + 0 ID=cds-YP_010377182.1;Parent=gene-NBT03_gp178;Dbxref=Genbank:YP_010377182.1,GeneID:72551594;Name=YP_010377182.1;Note=J3R%3B similar to Vaccinia virus strain Copenhagen B29R%3B CC-chemokine binding;gbkey=CDS;gene_name=OPG001;locus_tag=NBT03_gp178;product=MPXVgp191;protein_id=YP_010377182.1 diff --git a/data/nextstrain/mpx/hmpxv/NC_063383.1/reference.fasta b/data/nextstrain/mpx/hmpxv/NC_063383.1/reference.fasta deleted file mode 100644 index 903d879d..00000000 --- a/data/nextstrain/mpx/hmpxv/NC_063383.1/reference.fasta +++ /dev/null @@ -1,2820 +0,0 @@ ->NC_063383.1 Monkeypox virus, complete genome -ATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAA -GAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGA -AAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGA -AAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTA -ATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGG -ATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAAT -TATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACG -AGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTG -AGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACC -AAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACT -TTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTG -GTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGAC -ACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCG -ACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAA -ACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTT -ATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTG -ATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCT -TACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGA -TGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTG -GTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATT -GACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATG -ATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACT -AGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTC -TACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATT -ATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCG -CAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGT -AGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGT -TACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTG -TTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAA -AGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTT -ATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTA -CACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGA -CGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGAC -GTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTA -CACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGT -TACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATT -ATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTG -GAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACT -TTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATA -CGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTT -CTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCC -GTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAA -TACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTT -TATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGA -ATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCT -GAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGA -ATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAA -TGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCC -GACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAA -CGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGT -CGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCG -GTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTA -GTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTC -TTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCA -CAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTC -GAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGT -ATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCA -GCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGT -AGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTA -CAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTA -CTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGAT -AGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATAT -CTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGT -CGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATG -CGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTT -AGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATT -TACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTAT -GACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTA -ACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGG -GTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGG -AGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGA -CCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGA -ATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTA -TTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATG -ATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATG -GTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATT -TCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATG -TATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATA -ACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATAT -GGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTA -TTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACT -ACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGA -TCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCA -CAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATAT -AATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATC -CTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCC -TGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGA -TAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTG -CGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCT -CAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCT -TCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAA -AGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCC -TTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATT -ATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATT -TCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTG -ATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAG -ACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGAT -GTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTA -CAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATA -GTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCA -TCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAG -CATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATA -CATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAG -CGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTT -TACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTC -ACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGA -AATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATT -TACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATA -AACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCA -TTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAG -CTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATAT -CGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGAC -TATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAG -TAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACA -AGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAA -AAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATG -GGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGT -GGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTA -GTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTA -TCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGT -CAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCT -AGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAAC -CAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCA -ACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTT -GATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATA -ATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTT -AAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTT -ATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATC -AGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTC -ATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCC -ATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGT -TTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTT -ATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAA -TTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAA -ATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATC -ATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATC -ATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGG -AATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACC -AAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACA -AAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGA -CTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAA -TAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGAT -GTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATA -CACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTA -TAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGAT -AGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAA -CACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAG -CAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCT -CTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTC -CATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTT -TTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTAC -ATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCA -CCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGC -TAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATT -TGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGG -ATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTA -TTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGAT -TTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGT -ATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTT -AGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTC -AATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATG -TACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGA -TACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCA -ATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTG -AACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTC -TCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGG -CAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGG -ATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTT -TAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTT -ACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAA -TTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCT -CCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCT -AAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATG -TTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATC -TATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATT -CCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGAT -GAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTA -CTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCA -TCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTT -CTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATT -TATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTA -TTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTA -GTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAA -TTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCA -TTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCAC -AACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAA -AAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACT -TTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTA -TTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATAT -TAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAG -TACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCT -ATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTT -ATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATAT -ATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTT -TCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACAT -ATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTA -TAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGT -GCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAAT -TTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCA -ATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGG -CAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATC -GATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAAC -GGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTT -TAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTC -CCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGT -ATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTA -AAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTT -CCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAAT -AACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGAT -AAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACC -ATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTG -TAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTA -TGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATC -TATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCT -ATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATAT -CAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATT -ATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTT -TCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGT -TAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGC -ACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCA -ATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTA -CTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCT -TTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAA -CGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGA -AAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATC -TAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAA -GACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGG -CTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAA -CGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGA -CTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTT -TGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCAC -CGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATG -AATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTAT -GTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACT -GAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTT -TTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACAT -GTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTA -GGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTA -TTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTT -GATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACA -GTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTA -TATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGC -TGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATA -ACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAA -TGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATT -AATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAA -TGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTC -TATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCG -TCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTA -CGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACA -TATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAAC -GAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACAT -CTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGT -ATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCG -TGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAA -AAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAAC -GTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCG -CAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACT -TTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTA -TTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATC -TAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATC -TATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATA -TCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACA -TAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATC -GGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAA -ATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAG -ATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATC -AGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTT -AACAAGTTAACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTT -TATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTT -CCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAA -TTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTT -TACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTT -ATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCAT -TCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTA -ATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATA -ATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTT -CAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGAT -AGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACA -TTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCT -TATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAA -TGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTT -TAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGC -TAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTA -GTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTG -TAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCT -ATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAA -TACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGT -CTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAA -TCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCA -TCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTC -TCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTT -TTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAA -TCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCT -CATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAA -TCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTT -TTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATC -CACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATT -TAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGT -ATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAA -TTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGA -ATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCC -TTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGA -TGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTT -TCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATT -TAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAAT -AGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCAT -TATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATA -TTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTT -TGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAA -GAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTAT -AATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTT -GAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTC -TATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAA -CACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATC -TTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATA -GAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCT -ATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTAT -CCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGT -GATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTT -GGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATAT -TTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAA -GAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATG -ATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACA -CATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGC -TATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTT -ATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCC -ACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAG -CATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTAC -ACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTG -TATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAA -ATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAA -TGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCT -CGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGA -CTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGA -TTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAG -CCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAAT -CATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGA -GATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAG -TTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCAT -GTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCA -CTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTAT -CTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGC -ATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGT -TGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTT -TTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGAT -ATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCA -CTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATAT -TCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAA -ATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTG -TTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTA -AACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGT -TTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAA -TTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTA -GCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATT -TAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTT -AGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTA -TCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTAT -TAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTT -AATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATC -TTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCA -ATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGG -TGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCA -TTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGA -TTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTT -TATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCT -ATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATAT -AGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATG -CAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAA -GAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCAT -ATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAA -TCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATG -CTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTAC -CATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTT -ACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAG -ATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATC -TTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGAT -ACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAG -TACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGG -ATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATAC -CAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATT -CCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATAT -CCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCC -ATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTC -TTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACT -CCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTA -GTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCG -GATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTC -TTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTT -ATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTG -TTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAA -GACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACT -TCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCA -TAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCAT -TGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAAT -AAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACT -TACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATAC -TAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGA -CTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCA -GATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCA -TATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTA -CTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGA -TGATGAAATATGTAGTCGCGACTCCATCATTGATTTAATAGATGAATATATCACGTGGAGAAATCATGTT -ATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCG -CTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACAT -CAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAA -CATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCG -ACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAA -CGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTA -TATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTAT -CCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGT -AAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCC -AATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAA -ATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACA -ATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGT -TGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGT -TAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATC -ACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAAC -ATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGA -TTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTT -ACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTA -CACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTT -AGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCG -CTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAA -CAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACC -ATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGA -TCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGA -TAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCA -AGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTG -CCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTAT -ATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAG -CAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATT -GTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGAT -ATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTT -CTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTAT -GAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCAT -TTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGAT -TTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAAC -ATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCC -AGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATAC -CCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGAT -GATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACC -TTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAA -CTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATAT -CGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAAT -GCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCT -AAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAA -AATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTT -AAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATT -CCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAA -ATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAG -ACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAA -AATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCAT -AACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTAT -GGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCC -GAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTAC -AAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTAT -AAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACT -GTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAA -ATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTT -ATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGT -ATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGT -TATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCAC -GGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTT -TTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAG -TAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATA -TCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTT -CCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTT -CGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATT -CATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTAC -CTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAG -AAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGA -CATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAAC -AAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATT -TCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATC -ATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTA -TCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAA -CGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCT -TCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACA -CGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACAT -CTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTA -ATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAA -GAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGT -GGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCA -CATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTG -TTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTA -TTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGC -CAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAAC -CACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAA -TTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGG -AGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTA -CAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAG -CTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAG -TCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCT -ATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAA -AAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAA -TAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTT -GGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTT -AATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTT -TCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAA -AACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGT -TTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCT -GTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTAC -TTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTC -TTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTG -CCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAA -AACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGA -AGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGA -TTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTC -CATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATA -CCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGA -AAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATA -ATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATAT -AAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAAT -CATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATA -AACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATT -CACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAAT -AGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGA -TGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTC -CAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATG -CGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCT -TGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCT -AGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAA -AGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAG -CTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATC -TCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGT -AAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGG -TGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAA -ACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGAT -TTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGA -TAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTAC -AAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAAT -TGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTA -AAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCT -TGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGAC -TATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTA -TTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATAT -ATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGAT -ATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATA -GATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATA -CTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCAT -TAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCT -TTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTT -TACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAAT -AACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTAT -ACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCA -TAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATT -ACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCG -ATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATT -TAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATG -ATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGT -TTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTT -CTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGA -ACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATT -TCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTA -TAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACC -ACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCA -TAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTT -TCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTT -TTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTT -CCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAA -TAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGA -ATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCT -ATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCA -AATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCT -AGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATAC -GCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGG -CTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGT -TTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACC -CAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCG -GGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCC -TTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAA -AAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAAT -GATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGA -TGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCAT -CGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTC -CATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAA -TCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAA -GTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCT -CTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGC -CACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATC -GATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTT -TCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACT -ATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACAC -GTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATT -CAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTA -TCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATT -TTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTAT -CTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACA -TAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAA -CTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAA -CTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTAT -TATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTA -TTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGAC -AATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGT -AGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTC -CAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAG -ATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTAC -ACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTT -TTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAA -GGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAG -CTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAG -ATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTT -GCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAA -TAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCAT -CATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATA -TGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGA -AATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGT -GTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAG -CTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATAT -TATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTAC -ATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTC -AATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTAT -CCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAG -ATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGA -AAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAG -AATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATT -TTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAA -TTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTG -GAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAAT -CGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATT -TCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGT -CTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACT -AGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTC -CTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAG -TGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCT -TTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTT -TATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAAC -TAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGT -TCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAA -TAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCA -CAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGT -AATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAG -ACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCT -TTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGA -TTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGT -AAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGC -TTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATG -TAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTG -CTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTG -TATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCG -CAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATAT -CTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTT -CGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATA -TTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTA -TTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCAC -TATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGA -CATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGT -CAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTAT -TTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCA -ATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCA -TACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGC -AAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTA -AACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGAT -GAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATG -GCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGT -TAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAA -CTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTAC -AGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCG -TCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAAT -CTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTT -TTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCT -ATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAG -TATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTC -CATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAA -TCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAA -TAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGT -AGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCT -GGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTC -TAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGC -GGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTC -TCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTT -TCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAAT -CATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTT -TTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATT -TTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAA -GTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGT -TCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTT -ATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGT -TGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAG -AGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAA -TCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATG -ATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCT -CGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATG -TTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATAT -AGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATAC -TTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTC -AAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGA -ATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATA -TACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCA -ATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGC -TAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACAC -GCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATAC -AGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGA -CGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCC -ATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAA -GTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGA -TAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTT -AGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATG -CGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGAT -AAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGA -GAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACG -ATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAG -AACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATT -ATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATA -TATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAAT -CTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCC -ATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGT -TTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTA -TAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGA -TTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTT -CCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAG -CATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAA -CCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTT -GATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGAT -TTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCT -GAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTG -TAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATA -CGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACA -TATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACA -CATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGA -TAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTA -GAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGT -TTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAA -GTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAAT -TTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAG -TTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCA -TTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGA -GTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAG -TTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTA -GGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGG -TCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTAT -GAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGT -TTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAA -TCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAA -CATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGT -TTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCAT -ATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCG -TTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCT -GCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAA -ATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCC -TTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCT -CTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATT -TCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAA -ATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACA -TCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAAT -CTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGT -ATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATT -CTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCA -GACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGA -ACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGA -ATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAAT -GAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCT -ATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATAC -AGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGC -CTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAA -CAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCC -GCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAA -TACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTC -ATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCA -TTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGG -TTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTC -TCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTAC -GAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAA -CGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAG -ATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTA -GTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATT -GTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAG -CGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTA -ATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAA -TAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATC -GAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTT -GTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAA -TATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATC -TGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTC -ATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGT -AATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAA -TCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATT -TTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAG -CGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCC -TGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTAT -ATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAA -AGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGAT -TATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAA -ATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTA -TCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGT -ATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGAC -AAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTAT -TGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAAT -TCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTA -ACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGC -TATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATG -GTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGT -ATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAA -CAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCG -TATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTA -ATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGT -AAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACC -ATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCT -TTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAAT -GATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCC -TCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTC -TATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAA -TTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTA -TCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCT -CGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAA -ATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCC -ATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAG -GTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAG -ATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTA -AAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATT -CCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAA -AGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTA -ACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTT -CCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGA -CACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATG -AACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACC -CCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAA -TAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAA -TTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTT -AGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCA -ACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAA -CTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAA -AACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCAC -AGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCG -TAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTAT -GTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTT -TAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGC -GAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGG -GAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTG -ATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCG -CTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGA -TGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCC -ATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCAC -AATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTT -GTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAA -ATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTT -CACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTA -ACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTT -AACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTAC -AACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATAT -CAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCC -AGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTT -GTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTAC -TGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCAT -GGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAA -AGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGAT -ACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTT -ATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCA -GTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATT -TTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGA -TGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTG -TACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCAC -TGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTG -AATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAA -AAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGA -TGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAAC -TCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATC -TCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAG -ACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGC -AGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTT -AGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGG -CGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACC -GTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAG -AGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAG -CTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATC -CTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACAC -ACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTA -AATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTG -AGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTAT -AGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCA -ACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATC -TCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCAC -GGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTAT -TATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGC -ACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTG -TCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAG -TTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAAT -AGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACA -ATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGT -CTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGA -AATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAAT -AGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTT -GTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATAT -TCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTT -CTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTT -TTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAAT -TATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAAT -GATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCA -AAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATT -AGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATT -TTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGA -TACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTT -TGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGAT -ATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCG -CGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAAT -GGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTA -CCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTC -TCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAG -TATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTA -TTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTA -TAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATC -ATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGT -ATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAA -CATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAA -GGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGAC -TTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTA -TCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTAT -CCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTT -ATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTA -CACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAA -TACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATT -ATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAA -TGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAA -TTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTT -GTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAG -TTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGT -TCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATT -TTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCC -TTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGA -CATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCT -ACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACT -TTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATA -CATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGG -TATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTT -TTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACG -GAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAA -AACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAA -ACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTAT -AGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAG -AAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGG -GAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTA -GCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCA -AGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGA -AAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCA -TTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAA -ACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTA -TGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGA -AAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAA -AAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATT -TATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACT -GCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTC -ACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGA -TATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTG -GAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTT -TTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAA -TCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTT -CTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTA -CAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAA -TAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTC -GCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTC -TAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAAT -ATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAAT -ATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTT -TTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTAT -TATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCT -CAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAA -GACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACC -TGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGT -CAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGT -TTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTAT -GTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCAT -GTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATA -CTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTAT -CTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGT -ATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATAT -AAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAA -TACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGAT -AAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAA -TACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAG -TCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGA -CCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGAT -CCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTC -TCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCT -AAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGT -TTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATT -TACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATAT -AAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAA -ATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCA -TTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTT -TTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAA -CGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAAT -GATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAA -TAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTG -TTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAG -GATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAA -GGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTA -GTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAG -GTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCT -CAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATT -CTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAG -ATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTT -ATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAA -ACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGG -TGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGA -AACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATA -CTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATT -CTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTT -CATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAA -TTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTC -AGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATG -TAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTC -TAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGA -TTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTAT -CTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTAC -ATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACC -ACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATC -CTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAA -ATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAAC -TTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATT -ATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTT -AGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGAT -GAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCAT -TAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATAC -TAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACC -ATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTC -TGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAG -CTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCAT -TAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCA -ACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATG -CGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGA -AAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAA -GGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGA -ATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCA -TGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAA -CGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATG -ATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTC -CGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAA -AATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAAT -GGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGC -ATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATT -GGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCT -ATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTA -TATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACC -AGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATG -AGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGT -TCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTT -TAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAA -TTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTT -TTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGA -TTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGAT -ATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTG -TAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGC -CAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAA -TGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTT -CTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTT -CACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATG -TAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGA -TCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCAT -CTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATG -ACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTC -TCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAG -AGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGG -ATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATA -TGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTT -ATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCA -CTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCG -GTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCG -TACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGT -TGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCG -ATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACA -ATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAA -TTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGAC -AACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTC -ATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTA -ACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGA -TGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGT -CAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTA -TTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGA -CTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAA -ATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATG -TGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAA -CACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACAC -TGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTA -AAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTA -ATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCA -AATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTG -GCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTT -TAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTAT -TGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGC -TGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGT -CTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTA -TAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCT -AGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATC -TCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATA -ATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGG -CACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACC -TTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAAT -TGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGG -TAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAAC -ATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAG -AATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACA -TTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGA -GAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTT -CTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATC -ATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTA -TTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTT -CATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATC -GGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAG -AAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAA -ATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTG -GAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGG -GTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTAT -GCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAG -AACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATA -TTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATC -TAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTAC -GGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCC -CTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCT -AACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTG -TTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAG -TATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACG -AAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATC -TATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAG -ATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATG -ATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCAC -TCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGT -TATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGT -TTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGAT -TAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGAT -CCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAA -TTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTA -CAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAA -CGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAA -CTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAG -ACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGAC -ATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACT -GCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAA -TAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTT -TTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGT -TAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGA -GGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAG -TTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATAC -GTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCA -TGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGA -TCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAA -ATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCC -CGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACAC -GGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCG -GTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCT -TAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCAC -ATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTC -TACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAAT -ACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAAT -AAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTT -AGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGG -TTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGT -AAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAA -ACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAG -AGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAA -TAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGA -GATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAA -TAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAG -ATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTA -TCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTA -AAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATC -TATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCA -CAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAG -TTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGC -TGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGT -CATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTAT -GTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCA -TATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTA -TTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGAT -TAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAAT -TACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATC -TATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACT -TATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAG -TATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCT -GATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCA -GTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAA -AGATCAAACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACA -TATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTAT -TAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAA -GTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGT -ATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAG -GAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATG -GATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTC -AAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGT -TTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCC -TAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCG -GGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATC -TGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATC -TTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCG -ACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAAT -ATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATC -CATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGAT -GATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATA -TTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTT -ACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGA -TTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAA -CATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGG -ACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGT -AAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATA -AAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTT -CCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCAT -AACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATAT -TCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTT -CTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCT -GAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAAC -TTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATC -CGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCA -GACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGA -GAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAA -GGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTT -GAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTA -GTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAA -GATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCT -GGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAA -ACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAG -TTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGA -GATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCC -ACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCAT -GAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGAC -TTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGC -CTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGA -CATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCG -TTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTAT -CATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATT -TAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACA -TTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTA -AGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGC -ATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATA -TTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTA -ATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAAC -AAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTG -GATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAG -GTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTA -TTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGC -GGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTA -ACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACA -AAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGT -GTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTT -TCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCC -TGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTT -TATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATAC -CCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAA -TAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGT -AATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTA -AAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGT -TACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAA -CACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCA -TTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAG -GTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCAT -ATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAG -ATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTG -GTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTC -TTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGA -GTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTG -ATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACA -TGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTT -TGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATG -CGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGA -TACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTG -TATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAAT -CGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATA -AGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATC -TTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGA -ACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAG -AAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAA -GACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAG -TCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTAT -ATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTA -ATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGA -ATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTT -CACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAG -ATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGT -TATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAA -GAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATAC -TTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATC -TTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTC -TGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTA -ACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGAT -CATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTC -TTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCA -ATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGT -TGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAG -TAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAA -CAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAA -ATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCA -TTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGT -TTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATA -TTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACC -AGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAA -TATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAA -GCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAA -AGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTT -AAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTA -GACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGT -TGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTT -ACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAA -TTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTT -TGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCT -AAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATA -TAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTAT -TAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACAC -ATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTG -TTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCT -GTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTC -CGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTC -CATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAAT -TTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTA -TCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGAT -AATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTA -TGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCA -TCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTAT -AAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTA -GTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCC -CCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAG -CTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAA -AAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGT -ATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGA -ATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAG -GAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTA -AGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAA -ATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATA -TTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAA -AAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATT -GCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAAT -GAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTC -CAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATAT -AGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTT -ACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAA -TAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCT -AATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGAT -ATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCG -ATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATC -TAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATG -TCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAG -GCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTA -TTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATA -GCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAG -AAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGA -TGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTA -AATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCA -AGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGC -GATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACG -GATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCA -AGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGT -ATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACAT -TATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGG -ATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGA -AAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACT -CCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTG -TAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGA -AGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTC -GAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCT -GATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACT -GTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAA -AAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTA -TCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTA -TATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTAT -TTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGAC -GATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGG -AGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGG -GTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGA -TGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATA -CGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTA -TTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATT -TTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAAC -ATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAA -GTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAA -AAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGA -TGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGAC -GAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTG -TGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAA -ATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTT -AATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACG -CGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTG -TTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATAT -CATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAAT -TAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTG -TGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTC -AGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATT -GATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTT -TCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTAT -CGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAA -TCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTT -TAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATC -TGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGT -ACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACC -TATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGT -TCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTC -ATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATT -ATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGG -TGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAAT -AAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATA -TAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAAT -AAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCT -AACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATG -GTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATC -GACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATC -ATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTA -GTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGAC -AACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGAT -GTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAAC -TACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTG -TGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACT -AATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAA -CACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATT -AGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAA -TGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCAT -TCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTC -CAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCC -AAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCA -ATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATA -TTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGT -ATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACA -GAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGC -TTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATG -GGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTT -TTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTT -TATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAA -AACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTA -TAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGAC -ACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATG -CCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTC -ACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGA -TAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTA -TTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAAT -TGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACA -CTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATAT -TCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCG -TTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGG -CAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCAT -ATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAAT -TCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGA -CGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAG -CTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAA -CGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTA -TAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAA -GAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATA -AATCTCTTTTATACAAATACAAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGT -TTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGA -AATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGA -CATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCC -AAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAA -ACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGA -AGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTA -TCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCG -CCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATA -AGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGA -TATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCG -CACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTA -TACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTC -TGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGA -GTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAAT -ACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAAT -ATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGC -CTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACA -TCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATT -CATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTG -GATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTT -TTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATA -GCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTA -AACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATA -TCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCT -ATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGT -TGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGA -TAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTA -AAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTT -ATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAAT -TAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAAT -ATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACG -ACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGC -CTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTA -ACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATT -TCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCA -GCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTC -CAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCG -TTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGA -CGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATAT -TTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACT -TAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAA -AATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCG -TCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGG -AATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCT -TGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCAT -TCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAA -ATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCT -ACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCC -TCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAG -AAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTT -GATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAAT -AAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTC -CCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAAT -AGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTT -AATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTC -TTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGT -TTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATT -AATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTA -TGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAG -CGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACG -ATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATA -CTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATC -AATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTT -TGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCC -AAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATG -TTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATA -CTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCA -TCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCAT -TTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTT -GTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCG -TATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAA -ATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATC -CAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCAT -TTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATA -GAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGT -TAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGT -TCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCAT -AATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATC -ATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAG -TAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTT -CATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTAT -AGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGAT -ACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCA -TGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGG -CCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGT -TCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTC -TAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTT -GGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGA -ATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTAT -ATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACAT -TAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCA -TCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTG -GACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATC -TTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAG -AGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAG -GTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAAC -ATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGA -TTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAA -ACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGA -AATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATAT -AATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTAT -ATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAA -ATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCG -TTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGA -AGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTA -TTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGT -AACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTC -ATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGAC -GCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAA -TAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACAT -ATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACT -GCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTT -TTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACC -ATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTT -TCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAA -AAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATT -TCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAA -AGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATC -TACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACAT -TGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACT -TTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGA -TACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGT -CCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTT -TGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCC -GAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAA -TATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATT -AAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAG -CAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATA -AAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTT -CTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTAT -AATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGC -GGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATT -AGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACA -TCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAAT -GTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCA -TCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCA -TAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGC -CACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTC -ATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAAT -AAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTC -TGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAAC -ATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTA -CATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATT -AGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGG -AATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGT -CACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGC -GTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTT -AGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGAT -ATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGAT -GGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGT -TGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAG -ACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGA -TTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGT -TTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGT -TGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTG -TTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAG -ATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGT -GTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATAC -TTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGT -CATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGG -AGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTAT -TAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGT -CGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATC -ATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTT -CAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGA -GGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTA -TAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATG -ATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATC -AACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAA -CGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTC -AACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAAT -TATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAAC -GATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGAT -ATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTC -GTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATAT -TCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTAT -TAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAG -GCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCA -AATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAA -CGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAA -ACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAG -TCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAA -AACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAAT -CTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTA -AGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACAT -CATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATA -ACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTC -TCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGAC -CAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCAT -TATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACG -TCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCT -ATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATA -ACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATC -CATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATC -CTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATT -ACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAAT -ATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCG -TAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTA -TTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACA -TTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGAT -TTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATAT -TTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAA -ACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTT -CATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTA -GACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGG -CAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTT -TTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAA -ATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTA -TATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATT -AATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAAC -TGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACG -ACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGT -ACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAAC -ATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGC -ACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTT -TTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCC -AAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTA -ATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACT -TCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCT -ACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGG -GTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGG -AGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTT -TATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTC -TTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAA -AAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATC -AAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAG -AAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACG -TTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTT -TAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAAT -CTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTAT -TGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGT -GGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTA -AAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACT -GGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTC -TTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGG -CTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCT -ACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTA -TAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGT -GTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGA -GTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATG -TATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATG -CTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGT -GTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATC -GTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTG -TATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAAT -GTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTG -TATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCT -TAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGAT -ACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCG -GGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGT -CACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACT -ACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAG -ATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGA -TAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATA -AGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAAT -CGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAG -TTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGG -TAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTA -TTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAG -ACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTG -TTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACG -TTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGT -TTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAA -GTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCG -ACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATG -GCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGG -TTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCG -TTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAAT -AAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGG -TTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGA -GTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTG -GATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGT -ATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCT -AATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAAT -CTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAG -AGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACA -AAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGC -CAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTC -CAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGA -ACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATA -TCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGG -AATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAA -AAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGAT -AATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTA -TAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGA -GGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTC -ACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCA -AAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGC -ATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAA -CGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTG -TCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCA -GCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGC -CGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGC -GTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTT -GATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCAC -ATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACC -GATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTA -CTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTT -AACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCT -GGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGT -ATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATA -ACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGA -CACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAA -CTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAG -TATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAG -GCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCA -TAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATA -TAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAG -TAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGG -TGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACT -CTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAA -ACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGT -ACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTT -AGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAAC -CATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAG -TTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACA -CCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCG -TCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAAT -TCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGT -AAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATA -TCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGAT -CGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGG -ACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTT -TTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAG -GAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATG -AATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCT -ATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAA -ACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTAT -TCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAAC -TGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTC -AGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGA -ATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAA -TTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGT -TACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATA -GAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTAT -TTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGG -CATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCA -TCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTAT -AATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATT -TCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGT -AAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAAT -GCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCG -AATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTA -TCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAG -ACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAAC -TAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATA -TATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCA -GTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTA -ACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGT -AGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCT -AATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATA -CCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATAT -GGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAAT -AGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTT -ATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATAT -GCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTT -CCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTG -TAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAAC -ATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACG -ATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGAT -GTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACT -GTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAA -AAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACA -ATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTA -ACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGA -AATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGG -TACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCT -GATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAG -AGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAA -TGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTAT -TATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTG -GATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAA -CGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATAC -CAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTG -AAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATT -TCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTC -TCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAA -CAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATAC -ATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACT -AGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCT -CTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGA -TGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGAT -TTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAA -TAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAAC -TATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTC -GAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGAT -AACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAG -ATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATT -TATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATG -TCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCG -GATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAG -ATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAA -AAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGA -TATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGA -AAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAA -GAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAAC -GATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTA -CAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAA -GGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAG -TCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGA -GAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGA -AATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAG -GACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGT -TGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGC -TACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAAT -TTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAG -ATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGA -TTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAAT -AGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGA -TTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGA -CCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCA -AGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGAC -TCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACT -GTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAA -AAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAA -GTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAAT -CTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTT -CCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACA -ATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATAT -TTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATC -TAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATA -CATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATAT -GAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATAT -CTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTG -TCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGT -AACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAA -CAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTA -TCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGAT -CAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCAT -CAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAA -TATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGAT -GATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAA -ATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGT -AGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGA -CCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACG -ACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTAC -TTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGAT -TTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATT -CTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACG -AAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAA -ACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCA -ATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAA -GAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCG -AAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATA -TCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATA -TACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTA -TTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAG -TCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAA -TTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCT -ACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCG -ATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATC -GGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTT -TTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTA -AAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAAT -GGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAG -GATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACAT -GTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGT -ATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTT -TATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATC -AAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCT -CCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGA -AGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTC -GGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATAT -TCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATC -TACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAG -TTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCA -GATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCG -ATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACG -GCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATC -TCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCAT -TCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTT -TCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAA -TTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATC -ACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTG -TATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGA -AATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGT -TCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTG -TCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAG -TTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGAT -TCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTA -TCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAAC -TGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTT -TCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGT -CGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATT -GCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGT -ACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCA -CGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCAT -ACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGT -TGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAG -TATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTAT -AGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCT -TTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCT -TACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTT -AAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGT -TGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGT -ATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTT -ATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTAC -GCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACG -CGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAG -GATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTA -ACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTAT -ATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGG -AACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGT -AGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTAC -TAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAAC -AAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCG -AATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTC -CTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTG -CTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTA -GTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACT -CATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTT -CGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTA -GATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACA -GTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTC -TAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTT -AATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAA -GTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGG -TTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCT -TCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAG -TACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTT -GATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTT -TTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGC -TAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACT -AAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATA -GATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCAT -ATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAA -TTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGA -TCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCT -TACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAA -TGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAA -ATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGAT -ATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGC -TTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCT -TGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATA -TACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTA -GCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGC -GTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAG -CCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGA -TTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAG -TTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGG -ATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTT -CTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGT -TTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCT -CCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCC -TTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTA -CTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGC -GTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAAC -CTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACT -CTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTAT -TAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCT -ACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTA -TGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTAT -GTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATAT -TCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTAT -CCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTT -CAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTG -GGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAA -TGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAG -TTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGA -TTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGT -ACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTG -AGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCT -TTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATAC -CCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACT -TAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAA -CATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAG -GTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTA -CATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGA -CTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATT -ATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACT -ATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTT -ACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATT -CACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCAT -ATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCT -GAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAG -TTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACA -TTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCG -ACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAA -CGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATAT -ATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCT -CCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAAT -TCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAG -TAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACG -ACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAA -ACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCG -TTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCG -TTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTG -TAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAA -GCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATT -ATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGA -TGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAG -TAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGA -ACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAAC -ATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGC -TAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTA -AGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAA -CAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGT -TAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATG -AATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTG -ACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAG -GTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAG -CTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACA -GCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAAC -ATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTA -TACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCT -TCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCAT -AAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGA -GATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATAT -ATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAA -AGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGC -TATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGT -AGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTG -GAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAA -TGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTC -GTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTA -GTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGA -TGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAG -TATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCA -ATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGAT -CAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAG -ATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTA -TCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATC -CCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCC -AGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATT -TACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATT -TGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATA -GGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCG -AGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATT -GTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGG -GATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCT -TTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAA -TAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACT -AGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACA -GGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTT -TAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACA -GCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATG -TCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAA -CTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATC -GATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTT -GGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCC -GCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAA -TGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATAT -CATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATC -ATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAAT -ATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTA -ACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGT -AACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAAT -AACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATA -ACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCA -TCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAA -GGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAG -CCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAG -CTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAAC -TGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCG -TTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATT -CTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATT -TTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAG -GAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATC -CACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATA -GAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGT -ATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGA -TACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCT -TCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTT -CACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTG -TTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTT -ATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGC -TAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGC -ATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTAC -AAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTC -ATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAA -TGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAG -AACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGT -AGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAA -TTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCT -CATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTA -TAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACG -TTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTT -GTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGT -AAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACT -TATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAA -ATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGAT -CATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAA -AATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGAT -GTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAG -ATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTA -ATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAAT -CGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACA -TCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGT -TGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTT -GCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAAT -AGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCG -CAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCG -GCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAG -ACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGC -CATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATAC -ATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCT -ATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCT -GTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGC -CGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGT -ATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTT -CTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAAC -CGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTT -TGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTT -TAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCG -AGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCA -TATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATG -ATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAAT -TAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTAC -TCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGAC -AAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAG -AGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTT -TAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATG -ACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAG -ACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGT -AGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTA -GCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATC -TACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTC -TGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGAT -ATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAA -TTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATAT -ATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACA -CATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACAT -TAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTAT -TTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAAT -ACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGT -AGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATC -ATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTA -TTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGA -TGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGA -CTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGAT -CTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAA -TTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAA -TCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACT -TTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGA -TCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAA -CAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGT -CAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGG -TAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTA -CAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAG -ATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCA -ACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAA -GCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATC -AATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATT -TTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGA -TCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAAC -AAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATA -ATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTA -AACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAA -AAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACG -CATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATA -TTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATA -AAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAG -GAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTT -AGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTG -ACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAA -AAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATC -TAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATG -ACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAG -GAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATT -CTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCA -TTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTAC -CGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGA -CTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGAT -GTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAA -CTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATA -CGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCT -GCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAA -TGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATAC -GTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGG -TTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAA -TTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATT -TACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAA -TCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTTGCCATGGATGGT -GTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCA -TGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAA -CAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAA -AAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCG -GCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGT -CTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATT -CTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTA -TCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACA -TGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTA -TATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAA -ATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCT -TGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCT -GATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGG -TGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGG -TATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTAT -TTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCT -AGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCT -GATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCT -TAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTA -CTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATAT -AAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTG -CGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAA -ACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAAT -GTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTC -TGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCA -TAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATA -TACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAA -GTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTAC -ATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGT -AAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACC -TGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCAT -ACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTG -ATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCT -TCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAAT -AGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGA -CTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTAC -CATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCT -TTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGAT -AAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATC -TATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATA -GTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATC -TGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAA -TCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTA -ACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAG -TGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAAT -ATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAA -TGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAA -AATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTA -CTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTA -GTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCA -TATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCAT -AAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAA -TATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACA -TGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCC -AATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATA -GATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTT -GCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACT -AGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACG -ATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGA -ATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAAT -TAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACT -AATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATA -ATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGA -TTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAAT -CACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCT -TCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACT -ACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTT -GTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATC -ACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAA -ATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGAC -TATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCT -AATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACA -CCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGAT -TCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGT -ACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATA -ATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTT -CGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTAT -ATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATC -TGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTG -TTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAAC -GAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTA -GAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATA -ATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTA -CTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGG -ACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTAT -TCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGAC -CGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATAT -AACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAA -CTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGA -CAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACT -AATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTT -ATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCT -TATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGA -TTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGA -TCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGC -GAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAA -TTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAAT -TTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTG -TATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTA -AGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTA -GAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTT -TCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTT -ATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGA -GAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCA -GTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGAT -ATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCT -AGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTAC -GAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTAT -ATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGG -ACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGA -AAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAG -TTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCAC -CATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCAT -CTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATT -CATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCT -TCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGA -CCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGG -AGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACA -TACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTT -GCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGG -TGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCA -TTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAG -ACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAG -AATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAA -ATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTA -GGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTA -TTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACA -TGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTT -CTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATA -ATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATT -CCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATG -ATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTAT -CATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACT -AATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATA -AGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGAT -GTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGG -ATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGAC -AACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACAC -CTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGT -TAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAA -CTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTG -ATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAA -CGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAAT -GGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAA -TAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTAC -TAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTAT -GATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAG -ATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAA -TACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTTGT -GTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATG -CTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGA -ACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACT -ACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACG -ATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGA -ATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTC -AGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAG -AAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCA -TGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAA -TGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTT -AAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTT -CGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTC -CCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGT -GGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACAT -GTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACT -CTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATG -GCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATA -ATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAAT -TAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGT -TGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGA -AGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATA -TAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGAT -GAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAA -AATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAG -CTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATT -GTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGC -ATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAA -AACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAA -TAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAAT -GAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATT -CCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCA -ACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCAC -AAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATG -AAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATT -CGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCAC -TTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTA -ATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGAC -TGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAAT -GTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTG -AACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAAC -TGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGC -AAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACAT -TCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTAT -AGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATT -ACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAG -AAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATC -TTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATA -TTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTT -GGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATG -TCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCA -AAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGA -AGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACT -CAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTA -GTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATT -TGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTAT -CTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCG -TCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGT -CTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACT -TTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTAC -AAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAG -ACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACAT -TGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAA -GTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATG -TCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATAC -ATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCC -AGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGA -AGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCAT -TGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGG -AAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGG -TATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGAT -ACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATAC -TAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGC -ACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGAT -GTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACAT -AGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTA -TATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGA -AGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTT -GACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGA -GAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAAT -CAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGG -AAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAAC -AAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATA -TGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCAT -GATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAA -GAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAG -TTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACT -GTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATAT -TAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGC -ATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTAT -TATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGG -TTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGA -TTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCA -ATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTG -ATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATT -TACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGC -GAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTG -GAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAAC -AGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTT -AAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAA -CTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGA -TGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTT -ACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCG -TTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATT -TTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCT -TCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGT -GACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCAT -ACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGT -GTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATC -CGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATG -CTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGA -GATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTC -TTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGT -ATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAAT -GTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCC -TCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAAT -GATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTA -TTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGT -CTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTA -TGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCT -TAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCT -GGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATGGG -CAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAA -TTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTC -CCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGA -GACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAA -ACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAG -CAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAAT -TTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATAT -ATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAA -TCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATAC -TGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTT -AGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGT -TTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTC -ATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGG -TATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGA -GTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTAC -TACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCC -ACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTA -GTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTAT -TGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATAC -TCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCC -GCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAG -ACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACA -TGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACA -AAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAA -CATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTA -TAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGA -AAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACG -ACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCA -CAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGT -GCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAG -GATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGA -AAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACT -CTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATT -AATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGAT -AGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGAT -GTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATA -CAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTAT -GATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAAT -TCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGA -TGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATT -AATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCG -TATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAA -GATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAA -ACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATT -CTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACT -TTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGA -ACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAG -TACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAA -ACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCT -AATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAG -GTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATA -TGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCA -AATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTA -CTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCG -AGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGAT -GGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTC -AGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATT -TGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAA -AGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGC -AGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTAT -CGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAG -TATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCA -CTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGA -CAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACA -TTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATT -TGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCT -ATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACA -CAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGAT -TATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGC -AATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCG -CATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAG -ATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATA -CAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAAC -TATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGT -TATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCG -GTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGC -TGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAG -ATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACAC -GAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTT -CATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTA -CGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGAT -TTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTA -ACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATT -ATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACA -TTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGA -TATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCT -ACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATA -TGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGC -GACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAA -ATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGG -TTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGAT -AGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGAC -AAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAAT -ATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTAT -GGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTT -AAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGA -CGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGA -TTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAAT -GAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGA -AGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAA -ATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAA -TAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGT -ATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACG -GATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCC -CATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGAC -TATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCA -CACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATT -GTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAG -AAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATA -TGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGG -AGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGA -TTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACAT -GAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACC -AGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTC -TATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAA -TTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGT -TGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTA -TCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAG -GGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTG -TTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTAT -ATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCA -CCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTA -TATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCA -TAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGT -AATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACAT -TAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATC -TTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACA -CAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAG -TTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATA -TTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAAC -ATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATG -ATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATAT -AAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTA -TTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAG -GTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAG -TCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTA -AATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAA -ACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGT -TCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGT -GATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACAC -AGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGG -CAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACA -ACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTA -ATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTAC -AAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCT -CCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGAC -CAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAG -ACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTAT -TCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATG -TTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGA -TAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCA -ACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTAT -CAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGC -TATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGG -CCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTG -TAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAA -ACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACA -TCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGG -ACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGC -AACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCG -TACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAAT -CTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTA -TGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAG -TTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTA -GCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAA -TAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGA -ACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTC -CAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACC -TGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACA -CATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCAT -TTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCC -GTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAA -GATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTA -TTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGA -CAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATAT -AGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATG -GAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATAC -ATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACT -GTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTA -CATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGA -TAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAA -GATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATA -CATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGA -ATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATAT -AGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAG -CAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACAT -ACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGAC -ATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACT -ATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATC -CTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCA -TGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAG -CAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAAT -AAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACT -ATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGA -AATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTC -TATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAAT -TTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCAT -ATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATT -AATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTC -TAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGAC -CTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACAT -GAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCT -TTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAA -TTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAA -CTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTC -CGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAA -CGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTA -TTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCT -ATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGG -AACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTC -ACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAAT -AGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTG -CTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGA -AATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGA -CTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTAT -TAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTT -CGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATG -ACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTC -TACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAA -GGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACA -GACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTC -TGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCT -CTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCT -GGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCAT -TTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCC -ATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCC -TCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCT -TGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGAC -ATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTA -CAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAAT -TCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGA -AAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTT -CAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTC -TTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTAC -ACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTA -GCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATT -ATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAA -TTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAG -AGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTA -CTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCA -CTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCG -ACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCA -TGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATC -AAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAA -AAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATT -GTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATT -GCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGT -AATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAA -GTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACA -ACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGT -TGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGAT -CTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAAT -ATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCG -AATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGA -CCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTT -CTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATG -TTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATA -TATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATT -ATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACA -TTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGG -AATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTT -AAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAA -TTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTA -TCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCA -GTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAG -CACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACT -TAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCA -CTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTA -GGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTC -CCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTAC -ACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATG -TATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGT -CATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTT -AGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAA -GTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTT -CTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGA -TAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAAT -GTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAAC -ACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATT -TAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGA -CATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGG -ACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAG -CTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGA -CTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGA -GTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGC -GGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTG -GTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGG -AATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATA -CGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGA -AGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATA -CAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGG -ATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATT -ATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAAT -CGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTG -CCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTA -TTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCC -TCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACAC -ATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGT -CATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATA -GTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCA -TCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAA -ATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCAT -GAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCA -CATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTC -CTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGA -TACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAG -GTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTC -TCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGG -ATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCC -ACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATC -CAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACT -AACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAAT -GTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATT -TCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCAT -GCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGT -AATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATA -GCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTA -AGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTT -ATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTG -TCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTAC -TGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCG -ACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAG -TTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCAC -CAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGC -GTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACT -GTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACT -TGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAA -TGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCA -AGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTC -AACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCG -AACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATA -TTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGA -TCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAAAAATATTTTTATTCTC -TTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATA -ACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCA -TCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAA -TATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACA -AGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATA -TCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTC -GTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTC -TATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACA -CTAAATAAAATAGTAAAAT - diff --git a/data/nextstrain/mpx/hmpxv/NC_063383.1/tree.json b/data/nextstrain/mpx/hmpxv/NC_063383.1/tree.json deleted file mode 100644 index c3b0e5bc..00000000 --- a/data/nextstrain/mpx/hmpxv/NC_063383.1/tree.json +++ /dev/null @@ -1,106766 +0,0 @@ -{ - "version": "v2", - "meta": { - "title": "Nextclade reference tree for HPXV-1 (reference seq: NC_063383.1)", - "updated": "2023-07-31", - "build_url": "https://github.com/nextstrain/monkeypox", - "data_provenance": [ - { - "name": "GenBank", - "url": "https://www.ncbi.nlm.nih.gov/genbank/" - } - ], - "maintainers": [ - { - "name": "Nextstrain team", - "url": "http://nextstrain.org" - } - ], - "display_defaults": { - "color_by": "lineage", - "map_triplicate": false, - "distance_measure": "div", - "transmission_lines": false - }, - "genome_annotations": { - "nuc": { - "end": 197209, - "start": 1, - "strand": "+", - "seqid": "config/genemap.gff", - "type": "source" - }, - "NBT03_gp052": { - "end": 55141, - "seqid": "config/genemap.gff", - "start": 54752, - "strand": "+", - "type": "gene" - }, - "NBT03_gp174": { - "end": 190940, - "seqid": "config/genemap.gff", - "start": 190410, - "strand": "+", - "type": "gene" - }, - "NBT03_gp175": { - "end": 192367, - "seqid": "config/genemap.gff", - "start": 191054, - "strand": "+", - "type": "gene" - }, - "OPG001": { - "end": 196375, - "seqid": "config/genemap.gff", - "start": 195635, - "strand": "+", - "type": "gene" - }, - "OPG002": { - "end": 195508, - "seqid": "config/genemap.gff", - "start": 194459, - "strand": "+", - "type": "gene" - }, - "OPG003": { - "end": 194369, - "seqid": "config/genemap.gff", - "start": 192603, - "strand": "+", - "type": "gene" - }, - "OPG005": { - "end": 189660, - "seqid": "config/genemap.gff", - "start": 189199, - "strand": "+", - "type": "gene" - }, - "OPG015": { - "end": 6156, - "seqid": "config/genemap.gff", - "start": 4843, - "strand": "+", - "type": "gene" - }, - "OPG019": { - "end": 8008, - "seqid": "config/genemap.gff", - "start": 7580, - "strand": "+", - "type": "gene" - }, - "OPG021": { - "end": 10315, - "seqid": "config/genemap.gff", - "start": 9587, - "strand": "+", - "type": "gene" - }, - "OPG022": { - "end": 10858, - "seqid": "config/genemap.gff", - "start": 10478, - "strand": "+", - "type": "gene" - }, - "OPG023": { - "end": 12900, - "seqid": "config/genemap.gff", - "start": 10918, - "strand": "+", - "type": "gene" - }, - "OPG024": { - "end": 13228, - "seqid": "config/genemap.gff", - "start": 13034, - "strand": "+", - "type": "gene" - }, - "OPG025": { - "end": 15267, - "seqid": "config/genemap.gff", - "start": 13375, - "strand": "+", - "type": "gene" - }, - "OPG027": { - "end": 16377, - "seqid": "config/genemap.gff", - "start": 15925, - "strand": "+", - "type": "gene" - }, - "OPG029": { - "end": 17069, - "seqid": "config/genemap.gff", - "start": 16602, - "strand": "+", - "type": "gene" - }, - "OPG030": { - "end": 17833, - "seqid": "config/genemap.gff", - "start": 17213, - "strand": "+", - "type": "gene" - }, - "OPG031": { - "end": 18828, - "seqid": "config/genemap.gff", - "start": 17878, - "strand": "+", - "type": "gene" - }, - "OPG034": { - "end": 20005, - "seqid": "config/genemap.gff", - "start": 19361, - "strand": "+", - "type": "gene" - }, - "OPG035": { - "end": 20404, - "seqid": "config/genemap.gff", - "start": 20051, - "strand": "+", - "type": "gene" - }, - "OPG036": { - "end": 21064, - "seqid": "config/genemap.gff", - "start": 20531, - "strand": "+", - "type": "gene" - }, - "OPG037": { - "end": 22433, - "seqid": "config/genemap.gff", - "start": 21105, - "strand": "+", - "type": "gene" - }, - "OPG038": { - "end": 23159, - "seqid": "config/genemap.gff", - "start": 22497, - "strand": "+", - "type": "gene" - }, - "OPG039": { - "end": 24118, - "seqid": "config/genemap.gff", - "start": 23264, - "strand": "+", - "type": "gene" - }, - "OPG040": { - "end": 25478, - "seqid": "config/genemap.gff", - "start": 24351, - "strand": "+", - "type": "gene" - }, - "OPG042": { - "end": 27097, - "seqid": "config/genemap.gff", - "start": 25823, - "strand": "+", - "type": "gene" - }, - "OPG043": { - "end": 27955, - "seqid": "config/genemap.gff", - "start": 27125, - "strand": "+", - "type": "gene" - }, - "OPG044": { - "end": 28540, - "seqid": "config/genemap.gff", - "start": 28091, - "strand": "+", - "type": "gene" - }, - "OPG045": { - "end": 29262, - "seqid": "config/genemap.gff", - "start": 28603, - "strand": "+", - "type": "gene" - }, - "OPG046": { - "end": 29729, - "seqid": "config/genemap.gff", - "start": 29274, - "strand": "+", - "type": "gene" - }, - "OPG047": { - "end": 31194, - "seqid": "config/genemap.gff", - "start": 29746, - "strand": "+", - "type": "gene" - }, - "OPG048": { - "end": 32164, - "seqid": "config/genemap.gff", - "start": 31205, - "strand": "+", - "type": "gene" - }, - "OPG049": { - "end": 33151, - "seqid": "config/genemap.gff", - "start": 32195, - "strand": "+", - "type": "gene" - }, - "OPG050": { - "end": 33408, - "seqid": "config/genemap.gff", - "start": 33181, - "strand": "+", - "type": "gene" - }, - "OPG051": { - "end": 33649, - "seqid": "config/genemap.gff", - "start": 33425, - "strand": "+", - "type": "gene" - }, - "OPG052": { - "end": 33995, - "seqid": "config/genemap.gff", - "start": 33801, - "strand": "+", - "type": "gene" - }, - "OPG053": { - "end": 34690, - "seqid": "config/genemap.gff", - "start": 34052, - "strand": "+", - "type": "gene" - }, - "OPG054": { - "end": 35996, - "seqid": "config/genemap.gff", - "start": 34677, - "strand": "+", - "type": "gene" - }, - "OPG055": { - "end": 37083, - "seqid": "config/genemap.gff", - "start": 36019, - "strand": "+", - "type": "gene" - }, - "OPG056": { - "end": 39034, - "seqid": "config/genemap.gff", - "start": 37127, - "strand": "+", - "type": "gene" - }, - "OPG057": { - "end": 40195, - "seqid": "config/genemap.gff", - "start": 39077, - "strand": "+", - "type": "gene" - }, - "OPG058": { - "end": 40434, - "seqid": "config/genemap.gff", - "start": 40213, - "strand": "+", - "type": "gene" - }, - "OPG059": { - "end": 40633, - "seqid": "config/genemap.gff", - "start": 40484, - "strand": "+", - "type": "gene" - }, - "OPG060": { - "end": 41182, - "seqid": "config/genemap.gff", - "start": 40706, - "strand": "+", - "type": "gene" - }, - "OPG061": { - "end": 41884, - "seqid": "config/genemap.gff", - "start": 41189, - "strand": "+", - "type": "gene" - }, - "OPG062": { - "end": 42252, - "seqid": "config/genemap.gff", - "start": 41947, - "strand": "+", - "type": "gene" - }, - "OPG063": { - "end": 43688, - "seqid": "config/genemap.gff", - "start": 42249, - "strand": "+", - "type": "gene" - }, - "OPG064": { - "end": 45898, - "seqid": "config/genemap.gff", - "start": 43685, - "strand": "+", - "type": "gene" - }, - "OPG065": { - "end": 46483, - "seqid": "config/genemap.gff", - "start": 46022, - "strand": "+", - "type": "gene" - }, - "OPG066": { - "end": 47428, - "seqid": "config/genemap.gff", - "start": 46649, - "strand": "+", - "type": "gene" - }, - "OPG068": { - "end": 49904, - "seqid": "config/genemap.gff", - "start": 48201, - "strand": "+", - "type": "gene" - }, - "OPG069": { - "end": 50486, - "seqid": "config/genemap.gff", - "start": 49986, - "strand": "+", - "type": "gene" - }, - "OPG070": { - "end": 51411, - "seqid": "config/genemap.gff", - "start": 50590, - "strand": "+", - "type": "gene" - }, - "OPG071": { - "end": 54438, - "seqid": "config/genemap.gff", - "start": 51418, - "strand": "+", - "type": "gene" - }, - "OPG072": { - "end": 54757, - "seqid": "config/genemap.gff", - "start": 54470, - "strand": "+", - "type": "gene" - }, - "OPG074": { - "end": 57125, - "seqid": "config/genemap.gff", - "start": 55128, - "strand": "+", - "type": "gene" - }, - "OPG075": { - "end": 57498, - "seqid": "config/genemap.gff", - "start": 57172, - "strand": "+", - "type": "gene" - }, - "OPG076": { - "end": 57630, - "seqid": "config/genemap.gff", - "start": 57523, - "strand": "+", - "type": "gene" - }, - "OPG077": { - "end": 58583, - "seqid": "config/genemap.gff", - "start": 57645, - "strand": "+", - "type": "gene" - }, - "OPG078": { - "end": 58811, - "seqid": "config/genemap.gff", - "start": 58590, - "strand": "+", - "type": "gene" - }, - "OPG079": { - "end": 59621, - "seqid": "config/genemap.gff", - "start": 58812, - "strand": "+", - "type": "gene" - }, - "OPG080": { - "end": 62018, - "seqid": "config/genemap.gff", - "start": 59703, - "strand": "+", - "type": "gene" - }, - "OPG081": { - "end": 62285, - "seqid": "config/genemap.gff", - "start": 62046, - "strand": "+", - "type": "gene" - }, - "OPG082": { - "end": 63452, - "seqid": "config/genemap.gff", - "start": 62304, - "strand": "+", - "type": "gene" - }, - "OPG083": { - "end": 64716, - "seqid": "config/genemap.gff", - "start": 63445, - "strand": "+", - "type": "gene" - }, - "OPG084": { - "end": 66752, - "seqid": "config/genemap.gff", - "start": 64722, - "strand": "+", - "type": "gene" - }, - "OPG085": { - "end": 68531, - "seqid": "config/genemap.gff", - "start": 66756, - "strand": "+", - "type": "gene" - }, - "OPG086": { - "end": 68863, - "seqid": "config/genemap.gff", - "start": 68528, - "strand": "+", - "type": "gene" - }, - "OPG087": { - "end": 69519, - "seqid": "config/genemap.gff", - "start": 68857, - "strand": "+", - "type": "gene" - }, - "OPG088": { - "end": 69863, - "seqid": "config/genemap.gff", - "start": 69489, - "strand": "+", - "type": "gene" - }, - "OPG089": { - "end": 71170, - "seqid": "config/genemap.gff", - "start": 69866, - "strand": "+", - "type": "gene" - }, - "OPG090": { - "end": 71370, - "seqid": "config/genemap.gff", - "start": 71179, - "strand": "+", - "type": "gene" - }, - "OPG091": { - "end": 71867, - "seqid": "config/genemap.gff", - "start": 71370, - "strand": "+", - "type": "gene" - }, - "OPG092": { - "end": 72947, - "seqid": "config/genemap.gff", - "start": 71832, - "strand": "+", - "type": "gene" - }, - "OPG093": { - "end": 73760, - "seqid": "config/genemap.gff", - "start": 72978, - "strand": "+", - "type": "gene" - }, - "OPG094": { - "end": 74802, - "seqid": "config/genemap.gff", - "start": 73780, - "strand": "+", - "type": "gene" - }, - "OPG095": { - "end": 75555, - "seqid": "config/genemap.gff", - "start": 74803, - "strand": "+", - "type": "gene" - }, - "OPG096": { - "end": 75865, - "seqid": "config/genemap.gff", - "start": 75587, - "strand": "+", - "type": "gene" - }, - "OPG097": { - "end": 76875, - "seqid": "config/genemap.gff", - "start": 75841, - "strand": "+", - "type": "gene" - }, - "OPG098": { - "end": 77655, - "seqid": "config/genemap.gff", - "start": 76900, - "strand": "+", - "type": "gene" - }, - "OPG099": { - "end": 78051, - "seqid": "config/genemap.gff", - "start": 77665, - "strand": "+", - "type": "gene" - }, - "OPG100": { - "end": 78466, - "seqid": "config/genemap.gff", - "start": 78008, - "strand": "+", - "type": "gene" - }, - "OPG101": { - "end": 79019, - "seqid": "config/genemap.gff", - "start": 78486, - "strand": "+", - "type": "gene" - }, - "OPG102": { - "end": 80086, - "seqid": "config/genemap.gff", - "start": 79085, - "strand": "+", - "type": "gene" - }, - "OPG103": { - "end": 80558, - "seqid": "config/genemap.gff", - "start": 80001, - "strand": "+", - "type": "gene" - }, - "OPG104": { - "end": 81019, - "seqid": "config/genemap.gff", - "start": 80618, - "strand": "+", - "type": "gene" - }, - "OPG105": { - "end": 84986, - "seqid": "config/genemap.gff", - "start": 81126, - "strand": "+", - "type": "gene" - }, - "OPG106": { - "end": 85498, - "seqid": "config/genemap.gff", - "start": 84983, - "strand": "+", - "type": "gene" - }, - "OPG107": { - "end": 86081, - "seqid": "config/genemap.gff", - "start": 85512, - "strand": "+", - "type": "gene" - }, - "OPG108": { - "end": 87059, - "seqid": "config/genemap.gff", - "start": 86085, - "strand": "+", - "type": "gene" - }, - "OPG109": { - "end": 89447, - "seqid": "config/genemap.gff", - "start": 87060, - "strand": "+", - "type": "gene" - }, - "OPG110": { - "end": 90264, - "seqid": "config/genemap.gff", - "start": 89632, - "strand": "+", - "type": "gene" - }, - "OPG111": { - "end": 91209, - "seqid": "config/genemap.gff", - "start": 90265, - "strand": "+", - "type": "gene" - }, - "OPG112": { - "end": 91687, - "seqid": "config/genemap.gff", - "start": 91247, - "strand": "+", - "type": "gene" - }, - "OPG113": { - "end": 94268, - "seqid": "config/genemap.gff", - "start": 91731, - "strand": "+", - "type": "gene" - }, - "OPG114": { - "end": 94667, - "seqid": "config/genemap.gff", - "start": 94227, - "strand": "+", - "type": "gene" - }, - "OPG115": { - "end": 95361, - "seqid": "config/genemap.gff", - "start": 94660, - "strand": "+", - "type": "gene" - }, - "OPG116": { - "end": 96017, - "seqid": "config/genemap.gff", - "start": 95361, - "strand": "+", - "type": "gene" - }, - "OPG117": { - "end": 98406, - "seqid": "config/genemap.gff", - "start": 96049, - "strand": "+", - "type": "gene" - }, - "OPG118": { - "end": 100359, - "seqid": "config/genemap.gff", - "start": 98446, - "strand": "+", - "type": "gene" - }, - "OPG119": { - "end": 100871, - "seqid": "config/genemap.gff", - "start": 100386, - "strand": "+", - "type": "gene" - }, - "OPG120": { - "end": 101748, - "seqid": "config/genemap.gff", - "start": 100834, - "strand": "+", - "type": "gene" - }, - "OPG121": { - "end": 102431, - "seqid": "config/genemap.gff", - "start": 101790, - "strand": "+", - "type": "gene" - }, - "OPG122": { - "end": 103174, - "seqid": "config/genemap.gff", - "start": 102428, - "strand": "+", - "type": "gene" - }, - "OPG123": { - "end": 105070, - "seqid": "config/genemap.gff", - "start": 103175, - "strand": "+", - "type": "gene" - }, - "OPG124": { - "end": 105968, - "seqid": "config/genemap.gff", - "start": 105105, - "strand": "+", - "type": "gene" - }, - "OPG125": { - "end": 107654, - "seqid": "config/genemap.gff", - "start": 105999, - "strand": "+", - "type": "gene" - }, - "OPG126": { - "end": 108130, - "seqid": "config/genemap.gff", - "start": 107678, - "strand": "+", - "type": "gene" - }, - "OPG127": { - "end": 108825, - "seqid": "config/genemap.gff", - "start": 108151, - "strand": "+", - "type": "gene" - }, - "OPG128": { - "end": 109055, - "seqid": "config/genemap.gff", - "start": 108822, - "strand": "+", - "type": "gene" - }, - "OPG129": { - "end": 111004, - "seqid": "config/genemap.gff", - "start": 109070, - "strand": "+", - "type": "gene" - }, - "OPG130": { - "end": 111902, - "seqid": "config/genemap.gff", - "start": 111057, - "strand": "+", - "type": "gene" - }, - "OPG131": { - "end": 112425, - "seqid": "config/genemap.gff", - "start": 111940, - "strand": "+", - "type": "gene" - }, - "OPG132": { - "end": 113540, - "seqid": "config/genemap.gff", - "start": 112422, - "strand": "+", - "type": "gene" - }, - "OPG133": { - "end": 115696, - "seqid": "config/genemap.gff", - "start": 113564, - "strand": "+", - "type": "gene" - }, - "OPG134": { - "end": 116628, - "seqid": "config/genemap.gff", - "start": 115750, - "strand": "+", - "type": "gene" - }, - "OPG135": { - "end": 116911, - "seqid": "config/genemap.gff", - "start": 116609, - "strand": "+", - "type": "gene" - }, - "OPG136": { - "end": 119587, - "seqid": "config/genemap.gff", - "start": 116912, - "strand": "+", - "type": "gene" - }, - "OPG137": { - "end": 120558, - "seqid": "config/genemap.gff", - "start": 119602, - "strand": "+", - "type": "gene" - }, - "OPG138": { - "end": 121132, - "seqid": "config/genemap.gff", - "start": 120560, - "strand": "+", - "type": "gene" - }, - "OPG139": { - "end": 121368, - "seqid": "config/genemap.gff", - "start": 121156, - "strand": "+", - "type": "gene" - }, - "OPG140": { - "end": 121746, - "seqid": "config/genemap.gff", - "start": 121474, - "strand": "+", - "type": "gene" - }, - "OPG141": { - "end": 121924, - "seqid": "config/genemap.gff", - "start": 121763, - "strand": "+", - "type": "gene" - }, - "OPG142": { - "end": 122198, - "seqid": "config/genemap.gff", - "start": 121914, - "strand": "+", - "type": "gene" - }, - "OPG143": { - "end": 123315, - "seqid": "config/genemap.gff", - "start": 122182, - "strand": "+", - "type": "gene" - }, - "OPG144": { - "end": 123932, - "seqid": "config/genemap.gff", - "start": 123318, - "strand": "+", - "type": "gene" - }, - "OPG145": { - "end": 125425, - "seqid": "config/genemap.gff", - "start": 123947, - "strand": "+", - "type": "gene" - }, - "OPG146": { - "end": 125639, - "seqid": "config/genemap.gff", - "start": 125406, - "strand": "+", - "type": "gene" - }, - "OPG147": { - "end": 125987, - "seqid": "config/genemap.gff", - "start": 125640, - "strand": "+", - "type": "gene" - }, - "OPG148": { - "end": 127266, - "seqid": "config/genemap.gff", - "start": 125986, - "strand": "+", - "type": "gene" - }, - "OPG149": { - "end": 127759, - "seqid": "config/genemap.gff", - "start": 127196, - "strand": "+", - "type": "gene" - }, - "OPG150": { - "end": 128927, - "seqid": "config/genemap.gff", - "start": 127779, - "strand": "+", - "type": "gene" - }, - "OPG151": { - "end": 132418, - "seqid": "config/genemap.gff", - "start": 128924, - "strand": "+", - "type": "gene" - }, - "OPG153": { - "end": 137667, - "seqid": "config/genemap.gff", - "start": 136138, - "strand": "+", - "type": "gene" - }, - "OPG154": { - "end": 138050, - "seqid": "config/genemap.gff", - "start": 137718, - "strand": "+", - "type": "gene" - }, - "OPG155": { - "end": 138491, - "seqid": "config/genemap.gff", - "start": 138051, - "strand": "+", - "type": "gene" - }, - "OPG156": { - "end": 139409, - "seqid": "config/genemap.gff", - "start": 138492, - "strand": "+", - "type": "gene" - }, - "OPG157": { - "end": 139608, - "seqid": "config/genemap.gff", - "start": 139372, - "strand": "+", - "type": "gene" - }, - "OPG158": { - "end": 139769, - "seqid": "config/genemap.gff", - "start": 139641, - "strand": "+", - "type": "gene" - }, - "OPG159": { - "end": 140205, - "seqid": "config/genemap.gff", - "start": 139768, - "strand": "+", - "type": "gene" - }, - "OPG160": { - "end": 141074, - "seqid": "config/genemap.gff", - "start": 140172, - "strand": "+", - "type": "gene" - }, - "OPG161": { - "end": 141647, - "seqid": "config/genemap.gff", - "start": 141102, - "strand": "+", - "type": "gene" - }, - "OPG162": { - "end": 142158, - "seqid": "config/genemap.gff", - "start": 141652, - "strand": "+", - "type": "gene" - }, - "OPG163": { - "end": 142732, - "seqid": "config/genemap.gff", - "start": 142202, - "strand": "+", - "type": "gene" - }, - "OPG164": { - "end": 143464, - "seqid": "config/genemap.gff", - "start": 142778, - "strand": "+", - "type": "gene" - }, - "OPG165": { - "end": 144322, - "seqid": "config/genemap.gff", - "start": 143516, - "strand": "+", - "type": "gene" - }, - "OPG167": { - "end": 145407, - "seqid": "config/genemap.gff", - "start": 144574, - "strand": "+", - "type": "gene" - }, - "OPG170": { - "end": 146778, - "seqid": "config/genemap.gff", - "start": 146113, - "strand": "+", - "type": "gene" - }, - "OPG171": { - "end": 147389, - "seqid": "config/genemap.gff", - "start": 146988, - "strand": "+", - "type": "gene" - }, - "OPG172": { - "end": 148017, - "seqid": "config/genemap.gff", - "start": 147427, - "strand": "+", - "type": "gene" - }, - "OPG173": { - "end": 148261, - "seqid": "config/genemap.gff", - "start": 148037, - "strand": "+", - "type": "gene" - }, - "OPG174": { - "end": 149395, - "seqid": "config/genemap.gff", - "start": 148355, - "strand": "+", - "type": "gene" - }, - "OPG175": { - "end": 149819, - "seqid": "config/genemap.gff", - "start": 149442, - "strand": "+", - "type": "gene" - }, - "OPG176": { - "end": 150531, - "seqid": "config/genemap.gff", - "start": 149809, - "strand": "+", - "type": "gene" - }, - "OPG178": { - "end": 152123, - "seqid": "config/genemap.gff", - "start": 151509, - "strand": "+", - "type": "gene" - }, - "OPG180": { - "end": 154371, - "seqid": "config/genemap.gff", - "start": 152692, - "strand": "+", - "type": "gene" - }, - "OPG181": { - "end": 155416, - "seqid": "config/genemap.gff", - "start": 154412, - "strand": "+", - "type": "gene" - }, - "OPG185": { - "end": 159858, - "seqid": "config/genemap.gff", - "start": 158917, - "strand": "+", - "type": "gene" - }, - "OPG187": { - "end": 161533, - "seqid": "config/genemap.gff", - "start": 160622, - "strand": "+", - "type": "gene" - }, - "OPG188": { - "end": 163107, - "seqid": "config/genemap.gff", - "start": 161596, - "strand": "+", - "type": "gene" - }, - "OPG189": { - "end": 165018, - "seqid": "config/genemap.gff", - "start": 163333, - "strand": "+", - "type": "gene" - }, - "OPG190": { - "end": 166075, - "seqid": "config/genemap.gff", - "start": 165122, - "strand": "+", - "type": "gene" - }, - "OPG191": { - "end": 166667, - "seqid": "config/genemap.gff", - "start": 166161, - "strand": "+", - "type": "gene" - }, - "OPG192": { - "end": 167279, - "seqid": "config/genemap.gff", - "start": 166731, - "strand": "+", - "type": "gene" - }, - "OPG193": { - "end": 168137, - "seqid": "config/genemap.gff", - "start": 167334, - "strand": "+", - "type": "gene" - }, - "OPG195": { - "end": 168895, - "seqid": "config/genemap.gff", - "start": 168230, - "strand": "+", - "type": "gene" - }, - "OPG197": { - "end": 169972, - "seqid": "config/genemap.gff", - "start": 169670, - "strand": "+", - "type": "gene" - }, - "OPG198": { - "end": 170886, - "seqid": "config/genemap.gff", - "start": 170038, - "strand": "+", - "type": "gene" - }, - "OPG199": { - "end": 172022, - "seqid": "config/genemap.gff", - "start": 170988, - "strand": "+", - "type": "gene" - }, - "OPG200": { - "end": 172599, - "seqid": "config/genemap.gff", - "start": 172150, - "strand": "+", - "type": "gene" - }, - "OPG204": { - "end": 175587, - "seqid": "config/genemap.gff", - "start": 174532, - "strand": "+", - "type": "gene" - }, - "OPG205": { - "end": 178019, - "seqid": "config/genemap.gff", - "start": 175656, - "strand": "+", - "type": "gene" - }, - "OPG208": { - "end": 180339, - "seqid": "config/genemap.gff", - "start": 179266, - "strand": "+", - "type": "gene" - }, - "OPG209": { - "end": 181090, - "seqid": "config/genemap.gff", - "start": 180518, - "strand": "+", - "type": "gene" - }, - "OPG210": { - "end": 186998, - "seqid": "config/genemap.gff", - "start": 181356, - "strand": "+", - "type": "gene" - } - }, - "colorings": [ - { - "key": "clade_membership", - "title": "Clade", - "type": "categorical", - "scale": [ - [ - "IIb", - "#DEA73C" - ] - ] - }, - { - "key": "gt", - "title": "Genotype", - "type": "categorical" - }, - { - "key": "outbreak", - "title": "Outbreak", - "type": "categorical", - "scale": [ - [ - "hMPXV-1", - "#4C90C0" - ] - ] - }, - { - "key": "lineage", - "title": "Lineage", - "type": "categorical", - "scale": [ - [ - "A", - "#5E1D9D" - ], - [ - "A.1", - "#4D22AE" - ], - [ - "A.1.1", - "#4531BC" - ], - [ - "B.1", - "#4041C7" - ], - [ - "B.1.1", - "#3F53CD" - ], - [ - "B.1.2", - "#4064CF" - ], - [ - "B.1.3", - "#4375CD" - ], - [ - "C.1", - "#4784C8" - ], - [ - "B.1.4", - "#4C91BF" - ], - [ - "B.1.5", - "#539CB4" - ], - [ - "B.1.6", - "#5AA5A7" - ], - [ - "B.1.7", - "#63AC9A" - ], - [ - "B.1.8", - "#6CB28C" - ], - [ - "B.1.9", - "#77B67E" - ], - [ - "B.1.10", - "#82BA71" - ], - [ - "B.1.11", - "#8FBC66" - ], - [ - "B.1.12", - "#9CBE5B" - ], - [ - "B.1.13", - "#A9BD53" - ], - [ - "B.1.14", - "#B5BD4C" - ], - [ - "B.1.15", - "#C1BA46" - ], - [ - "B.1.16", - "#CDB642" - ], - [ - "B.1.17", - "#D6B03F" - ], - [ - "B.1.18", - "#DEA73B" - ], - [ - "B.1.19", - "#E39B39" - ], - [ - "B.1.20", - "#E68D36" - ], - [ - "A.2", - "#E67C33" - ], - [ - "A.2.1", - "#E5692F" - ], - [ - "A.2.2", - "#E1532B" - ], - [ - "A.2.3", - "#DE3E27" - ], - [ - "A.3", - "#DB2823" - ] - ] - }, - { - "key": "date", - "title": "Collection Date", - "type": "categorical" - }, - { - "key": "host", - "title": "Host", - "type": "categorical" - }, - { - "key": "strain", - "title": "Accession", - "type": "categorical" - }, - { - "key": "strain_original", - "title": "Strain name", - "type": "categorical" - }, - { - "key": "region", - "title": "Region", - "type": "categorical", - "scale": [ - [ - "Asia", - "#447CCD" - ], - [ - "Oceania", - "#5EA9A1" - ], - [ - "Africa", - "#8ABB6A" - ], - [ - "Europe", - "#BEBB48" - ], - [ - "South America", - "#E29E39" - ], - [ - "North America", - "#E2562B" - ] - ] - }, - { - "key": "country", - "title": "Country", - "type": "categorical", - "scale": [ - [ - "Israel", - "#5E1D9D" - ], - [ - "Singapore", - "#4A27B2" - ], - [ - "Vietnam", - "#4530BB" - ], - [ - "Taiwan", - "#3F45C8" - ], - [ - "South Korea", - "#3F51CC" - ], - [ - "Japan", - "#3E5CD0" - ], - [ - "Australia", - "#4067CF" - ], - [ - "Nigeria", - "#4E96BC" - ], - [ - "South Africa", - "#6FB388" - ], - [ - "Portugal", - "#85BA6F" - ], - [ - "Ireland", - "#8DBC68" - ], - [ - "Spain", - "#95BD61" - ], - [ - "United Kingdom", - "#9DBE5A" - ], - [ - "France", - "#A5BE55" - ], - [ - "Belgium", - "#AEBD50" - ], - [ - "Netherlands", - "#B6BD4B" - ], - [ - "Switzerland", - "#BEBB48" - ], - [ - "Germany", - "#CDB642" - ], - [ - "Italy", - "#D3B240" - ], - [ - "Slovenia", - "#D8AE3E" - ], - [ - "Sweden", - "#DDA83C" - ], - [ - "Austria", - "#E1A13A" - ], - [ - "Czech Republic", - "#E49938" - ], - [ - "Slovakia", - "#E69036" - ], - [ - "Finland", - "#E68534" - ], - [ - "Brazil", - "#E56E30" - ], - [ - "Peru", - "#E3602D" - ], - [ - "Colombia", - "#E1522A" - ], - [ - "Mexico", - "#DF4428" - ], - [ - "USA", - "#DD3625" - ], - [ - "Canada", - "#DB2823" - ] - ] - } - ], - "filters": [ - "clade_membership", - "lineage", - "country", - "host", - "institution", - "region" - ], - "panels": [ - "tree", - "entropy" - ], - "extensions": { - "nextclade": { - "clade_node_attrs": [ - { - "name": "outbreak", - "displayName": "Outbreak" - }, - { - "name": "lineage", - "displayName": "Lineage" - } - ] - } - } - }, - "tree": { - "name": "NODE_0000001", - "node_attrs": { - "div": 0, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": {}, - "labels": { - "clade": "A" - } - }, - "children": [ - { - "name": "MPXV-M5312_HM12_Rivers", - "node_attrs": { - "div": 0, - "author": { - "author": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Senkevich,T.G., Yutin,N., Wolf,Y.I., Koonin,E.V., Moss,B., Zmasek,C.M., Knipe,D.M., Pellett,P.E., Scheuermann,R.H.", - "value": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Senkevich,T.G., Yutin,N., Wolf,Y.I., Koonin,E.V., Moss,B., Zmasek,C.M., Knipe,D.M., Pellett,P.E., Scheuermann,R.H." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2018-08-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "National Center for Biotechnology Information, NIH" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV-M5312_HM12_Rivers" - }, - "strain": { - "value": "NC_063383" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000000", - "node_attrs": { - "div": 0, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": {} - }, - "children": [ - { - "name": "NC_063383.1", - "node_attrs": { - "div": 0, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000002", - "node_attrs": { - "div": 1, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T28175C", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-" - ] - } - }, - "children": [ - { - "name": "MPXV_Nigeria_2018_5232", - "node_attrs": { - "div": 1, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2018-01-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_Nigeria_2018_5232" - }, - "strain": { - "value": "OP535332" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV_Nigeria_2018_5231", - "node_attrs": { - "div": 4, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2018-01-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_Nigeria_2018_5231" - }, - "strain": { - "value": "OP535333" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T6635G", - "T6638G", - "T6660G" - ] - } - } - }, - { - "name": "NODE_0000003", - "node_attrs": { - "div": 5, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T593-", - "T594-", - "A18769G", - "A81977G", - "A100261G", - "T154408C", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "A196601-", - "A196602-" - ], - "OPG118": [ - "K606E" - ] - }, - "labels": { - "aa": "OPG118: K606E" - } - }, - "children": [ - { - "name": "KJ642617", - "node_attrs": { - "div": 38, - "author": { - "author": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Lil,Y., Weil,R.M., Muyembe,J.-J., Kingbeni,P.M., Balilo,M.", - "value": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Lil,Y., Weil,R.M., Muyembe,J.-J., Kingbeni,P.M., Balilo,M." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "1971-XX-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA" - }, - "clade_membership": { - "value": "outgroup" - }, - "strain_original": { - "value": "KJ642617" - }, - "strain": { - "value": "KJ642617" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T595-", - "A3450G", - "A8893C", - "G13625A", - "A18312G", - "T19367C", - "G32209-", - "A32210-", - "C32211-", - "T33143C", - "A38067G", - "A46895G", - "G48138A", - "A48527C", - "A53207C", - "A66580G", - "T80986C", - "C92516T", - "G98489-", - "C98727T", - "T100562C", - "C105126T", - "T119718C", - "A128076G", - "A129762G", - "T133145C", - "T136555C", - "A137627G", - "A140105-", - "T140106-", - "A140107-", - "A140108-", - "C140109-", - "A140110-", - "A140111-", - "T140112-", - "T140113-", - "A141300G", - "T141364C", - "A142450C", - "C146687T", - "T146862-", - "A146863-", - "T146864-", - "T146865-", - "T146866-", - "T146867-", - "A146868-", - "T146869-", - "A146870-", - "T146871-", - "T146872-", - "T146873-", - "T146874-", - "A146875-", - "T146876-", - "A146877-", - "T146878-", - "T146879-", - "T146880-", - "G149744A", - "G149878A", - "A158166-", - "G160174T", - "C160852T", - "A160867G", - "T166655-", - "T166656-", - "T167656G", - "C169722-", - "A169723-", - "G169724-", - "A169725-", - "T169726-", - "A169727-", - "A171675G", - "G174519-", - "A174520-", - "T174521-", - "G174522-", - "A174523-", - "A174524-", - "A178423G", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "A181246-", - "T187073-", - "T193760C", - "A196603-" - ], - "OPG025": [ - "T548M" - ], - "OPG049": [ - "R314X", - "H315X", - "*319X" - ], - "OPG056": [ - "V323A" - ], - "OPG071": [ - "L411W" - ], - "OPG084": [ - "Q620R" - ], - "OPG104": [ - "T12A" - ], - "OPG118": [ - "S15X", - "*638X" - ], - "OPG150": [ - "N100D" - ], - "OPG151": [ - "D280G" - ], - "OPG153": [ - "M14T", - "I371M" - ], - "OPG159": [ - "N113X", - "N114-", - "N115-", - "Y116X", - "*146X" - ], - "OPG161": [ - "K67E", - "V88A" - ], - "OPG170": [ - "G31D" - ], - "OPG176": [ - "D24N" - ], - "OPG191": [ - "Y165X", - "F166X", - "*169X" - ], - "OPG193": [ - "I108R" - ], - "OPG197": [ - "S18X", - "D19-", - "T20X", - "*101X" - ], - "OPG199": [ - "K230E" - ] - }, - "labels": { - "aa": "OPG025: T548M; OPG049: R314X, H315X, *319X; OPG056: V323A; OPG071: L411W; OPG084: Q620R; OPG104: T12A; OPG118: S15X, *638X; OPG150: N100D; OPG151: D280G; OPG153: M14T, I371M; OPG159: N113X, N114-, N115-, Y116X, *146X; OPG161: K67E, V88A; OPG170: G31D; OPG176: D24N; OPG191: Y165X, F166X, *169X; OPG193: I108R; OPG197: S18X, D19-, T20X, *101X; OPG199: K230E", - "clade": "outgroup" - } - } - }, - { - "name": "NODE_0000004", - "node_attrs": { - "div": 8, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "C5157T", - "G7764A", - "G9782A", - "C133161T", - "T146862-", - "A146863-", - "T146864-", - "T146865-", - "T146866-", - "T146867-", - "A146868-", - "T146869-", - "A146870-", - "T146871-", - "T146872-", - "T146873-", - "T146874-", - "A146875-", - "T146876-", - "A146877-", - "T146878-", - "T146879-", - "T146880-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "G192053A", - "-196602A" - ], - "NBT03_gp175": [ - "D334N" - ], - "OPG015": [ - "D334N" - ], - "OPG019": [ - "R62K" - ], - "OPG021": [ - "A66T" - ] - }, - "labels": { - "aa": "NBT03_gp175: D334N; OPG015: D334N; OPG019: R62K; OPG021: A66T" - } - }, - "children": [ - { - "name": "MK783028", - "node_attrs": { - "div": 8, - "author": { - "author": "Yinka-Ogunleye,A., Aruna,O., Dalhat,M., Ogoina,D., McCollum,A., Disu,Y., Mamadu,I., Akinpelu,A., Ahmad,A., Burga,J., Ndoreraho,A., Nkunzimana,E., Manneh,L., Mohammed,A., Adeoye,O., Tom-Aba,D., Silenou,B., Ipadeola,O., Saleh,M., Adeyemo,A., Nwadiutor,I., Aworabhi,N., Uke,P., John,D., Wakama,P., Reynolds,M., Mauldin,M., Doty,J., Wilkins,K., Musa,J., Khalakdina,A., Adedeji,A., Mba,N., Ojo,O., Krause,G., Ihekweazu,C., Mauldin,M.R., Li,Y., Gao,J.", - "value": "Yinka-Ogunleye,A., Aruna,O., Dalhat,M., Ogoina,D., McCollum,A., Disu,Y., Mamadu,I., Akinpelu,A., Ahmad,A., Burga,J., Ndoreraho,A., Nkunzimana,E., Manneh,L., Mohammed,A., Adeoye,O., Tom-Aba,D., Silenou,B., Ipadeola,O., Saleh,M., Adeyemo,A., Nwadiutor,I., Aworabhi,N., Uke,P., John,D., Wakama,P., Reynolds,M., Mauldin,M., Doty,J., Wilkins,K., Musa,J., Khalakdina,A., Adedeji,A., Mba,N., Ojo,O., Krause,G., Ihekweazu,C., Mauldin,M.R., Li,Y., Gao,J." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2017-11-09" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "NCEZID/DHCPP/PRB, Centers for Disease Control & Prevention (US CDC), USA" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MK783028" - }, - "strain": { - "value": "MK783028" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MK783031", - "node_attrs": { - "div": 9, - "author": { - "author": "Yinka-Ogunleye,A., Aruna,O., Dalhat,M., Ogoina,D., McCollum,A., Disu,Y., Mamadu,I., Akinpelu,A., Ahmad,A., Burga,J., Ndoreraho,A., Nkunzimana,E., Manneh,L., Mohammed,A., Adeoye,O., Tom-Aba,D., Silenou,B., Ipadeola,O., Saleh,M., Adeyemo,A., Nwadiutor,I., Aworabhi,N., Uke,P., John,D., Wakama,P., Reynolds,M., Mauldin,M., Doty,J., Wilkins,K., Musa,J., Khalakdina,A., Adedeji,A., Mba,N., Ojo,O., Krause,G., Ihekweazu,C., Mauldin,M.R., Li,Y., Gao,J.", - "value": "Yinka-Ogunleye,A., Aruna,O., Dalhat,M., Ogoina,D., McCollum,A., Disu,Y., Mamadu,I., Akinpelu,A., Ahmad,A., Burga,J., Ndoreraho,A., Nkunzimana,E., Manneh,L., Mohammed,A., Adeoye,O., Tom-Aba,D., Silenou,B., Ipadeola,O., Saleh,M., Adeyemo,A., Nwadiutor,I., Aworabhi,N., Uke,P., John,D., Wakama,P., Reynolds,M., Mauldin,M., Doty,J., Wilkins,K., Musa,J., Khalakdina,A., Adedeji,A., Mba,N., Ojo,O., Krause,G., Ihekweazu,C., Mauldin,M.R., Li,Y., Gao,J." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2017-11-09" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "NCEZID/DHCPP/PRB, Centers for Disease Control & Prevention (US CDC), USA" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MK783031" - }, - "strain": { - "value": "MK783031" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G109736A" - ] - } - } - } - ] - }, - { - "name": "NODE_0000005", - "node_attrs": { - "div": 13, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C8634T", - "C33332T", - "C67253T", - "C110326T", - "C117099T", - "C122737T", - "G125303A", - "G129583A", - "A136513-", - "T136514-", - "C136515-", - "T178041-", - "A179074-", - "T179075-", - "G179076-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-" - ], - "OPG050": [ - "R26Q" - ], - "OPG085": [ - "D427N" - ], - "OPG129": [ - "E227K" - ], - "OPG136": [ - "R830Q" - ], - "OPG145": [ - "D453N" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG050: R26Q; OPG085: D427N; OPG129: E227K; OPG136: R830Q; OPG145: D453N; OPG153: D385-" - } - }, - "children": [ - { - "name": "MPXV_Nigeria_2017_5205", - "node_attrs": { - "div": 27, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2017-12-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_Nigeria_2017_5205" - }, - "strain": { - "value": "OP535319" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C14067T", - "T146862-", - "A146863-", - "T146864-", - "T146865-", - "T146866-", - "T146867-", - "A146868-", - "T146869-", - "A146870-", - "T146871-", - "T146872-", - "T146873-", - "T146874-", - "A146875-", - "T146876-", - "A146877-", - "T146878-", - "T146879-", - "T146880-", - "G157078C", - "A157083C", - "T157101C", - "T157109C", - "T157112C", - "G157119C", - "C157126A", - "G157128A", - "G157129A", - "G157197A", - "G157200A", - "C157296T", - "C157729A", - "C169722-", - "A169723-", - "G169724-", - "A169725-", - "T169726-", - "A169727-", - "-179074A", - "-179075T", - "-179076G", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C" - ], - "OPG025": [ - "D401N" - ], - "OPG197": [ - "S18X", - "D19-", - "T20X", - "*101X" - ] - }, - "labels": { - "aa": "OPG025: D401N; OPG197: S18X, D19-, T20X, *101X" - } - } - }, - { - "name": "MPXV_Nigeria_2017_2915", - "node_attrs": { - "div": 13, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2017-10-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_Nigeria_2017_2915" - }, - "strain": { - "value": "OP535339" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "-196602A" - ] - } - } - } - ] - }, - { - "name": "NODE_0000006", - "node_attrs": { - "div": 8, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G51559A", - "C60923T", - "G179884A" - ], - "OPG080": [ - "E366K" - ], - "OPG208": [ - "E207K" - ] - }, - "labels": { - "aa": "OPG080: E366K; OPG208: E207K" - } - }, - "children": [ - { - "name": "MPXV_Nigeria_2017_5227", - "node_attrs": { - "div": 12, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2017-12-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_Nigeria_2017_5227" - }, - "strain": { - "value": "OP535318" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "C23311T", - "G75512A", - "G124715A", - "G162165A", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "-196602A" - ], - "OPG039": [ - "E270K" - ], - "OPG095": [ - "R237K" - ], - "OPG145": [ - "D257N" - ] - }, - "labels": { - "aa": "OPG039: E270K; OPG095: R237K; OPG145: D257N" - } - } - }, - { - "name": "MPXV_Nigeria_2018_5315", - "node_attrs": { - "div": 14, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2018-06-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_Nigeria_2018_5315" - }, - "strain": { - "value": "OP535326" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C23000T", - "G29826A", - "C109667T", - "A136513-", - "T136514-", - "C136515-", - "G147459A", - "G155644A", - "G177009A" - ], - "OPG038": [ - "G54S" - ], - "OPG047": [ - "R457C" - ], - "OPG153": [ - "D385-" - ], - "OPG205": [ - "E452K" - ] - }, - "labels": { - "aa": "OPG038: G54S; OPG047: R457C; OPG153: D385-; OPG205: E452K" - } - } - }, - { - "name": "NODE_0000007", - "node_attrs": { - "div": 10, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T146862-", - "A146863-", - "T146864-", - "T146865-", - "T146866-", - "T146867-", - "A146868-", - "T146869-", - "A146870-", - "T146871-", - "T146872-", - "T146873-", - "T146874-", - "A146875-", - "T146876-", - "A146877-", - "T146878-", - "T146879-", - "T146880-", - "A169723-", - "A169725-", - "T169726-", - "A169727-", - "G172784A", - "T181577C" - ], - "OPG197": [ - "S18X", - "D19X", - "T20X", - "*101X" - ] - }, - "labels": { - "aa": "OPG197: S18X, D19X, T20X, *101X" - } - }, - "children": [ - { - "name": "MPXV-M2940_FCT", - "node_attrs": { - "div": 10, - "author": { - "author": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y.", - "value": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2018-XX-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV-M2940_FCT" - }, - "strain": { - "value": "MT903337" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C169722-", - "G169724-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG197": [ - "X19-" - ] - }, - "labels": { - "aa": "OPG197: X19-" - } - } - }, - { - "name": "NODE_0000008", - "node_attrs": { - "div": 14, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G40586A", - "C67395T", - "C116175T", - "C160279T", - "-169723A", - "-169725A", - "-169726T", - "-169727A" - ], - "OPG197": [ - "X18S", - "X19D", - "X20T", - "X101*" - ] - }, - "labels": { - "aa": "OPG197: X18S, X19D, X20T, X101*" - } - }, - "children": [ - { - "name": "MPXV_Nigeria_2018_5218", - "node_attrs": { - "div": 17, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2018-02-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_Nigeria_2018_5218" - }, - "strain": { - "value": "OP535316" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T157146-", - "C157150A", - "T157151A", - "T157153A", - "T158117-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - }, - { - "name": "MPXV_Nigeria_2018_5301", - "node_attrs": { - "div": 14, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2018-02-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_Nigeria_2018_5301" - }, - "strain": { - "value": "OP535330" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-146862T", - "-146863A", - "-146864T", - "-146865T", - "-146866T", - "-146867T", - "-146868A", - "-146869T", - "-146870A", - "-146871T", - "-146872T", - "-146873T", - "-146874T", - "-146875A", - "-146876T", - "-146877A", - "-146878T", - "-146879T", - "-146880T" - ] - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000014", - "node_attrs": { - "div": 7, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G37209A", - "G48180A" - ], - "OPG056": [ - "S609F" - ] - }, - "labels": { - "aa": "OPG056: S609F" - } - }, - "children": [ - { - "name": "MPXV_Nigeria_2017_2944", - "node_attrs": { - "div": 16, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2017-10-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_Nigeria_2017_2944" - }, - "strain": { - "value": "OP535338" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "G10471T", - "T16609-", - "C16610-", - "A16611-", - "G17797A", - "C69627T", - "C72231T", - "G97984A", - "G106378A", - "C117119T", - "G161496A", - "C165497T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-196602A" - ], - "OPG029": [ - "D153X", - "D154X", - "*156X" - ], - "OPG030": [ - "L13F" - ], - "OPG117": [ - "D646N" - ], - "OPG125": [ - "P426L" - ], - "OPG187": [ - "R292Q" - ], - "OPG190": [ - "P126S" - ] - }, - "labels": { - "aa": "OPG029: D153X, D154X, *156X; OPG030: L13F; OPG117: D646N; OPG125: P426L; OPG187: R292Q; OPG190: P126S" - } - } - }, - { - "name": "NODE_0000015", - "node_attrs": { - "div": 11, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T595-", - "T596-", - "C8385T", - "G43118A", - "C113841T", - "A136513-", - "T136514-", - "C136515-", - "C146607T", - "A196603-", - "A196604-" - ], - "OPG133": [ - "G619E" - ], - "OPG153": [ - "D385-" - ], - "OPG170": [ - "E58K" - ] - }, - "labels": { - "aa": "OPG133: G619E; OPG153: D385-; OPG170: E58K" - } - }, - "children": [ - { - "name": "MPXV_Nigeria_2018_5316", - "node_attrs": { - "div": 14, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2018-06-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_Nigeria_2018_5316" - }, - "strain": { - "value": "OP535325" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-596T", - "T6690G", - "A6712C", - "A6745T", - "-136513A", - "-136514T", - "-136515C", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "-196604A" - ], - "OPG153": [ - "-385D" - ] - }, - "labels": { - "aa": "OPG153: -385D" - } - } - }, - { - "name": "MPXV_Nigeria_2018_5307", - "node_attrs": { - "div": 12, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2018-03-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_Nigeria_2018_5307" - }, - "strain": { - "value": "OP535327" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T6706G", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-" - ] - } - } - }, - { - "name": "MPXV_Nigeria_2018_5305", - "node_attrs": { - "div": 11, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2018-03-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_Nigeria_2018_5305" - }, - "strain": { - "value": "OP535329" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - }, - { - "name": "NODE_0000016", - "node_attrs": { - "div": 12, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G29889A", - "T76079-", - "A89100-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "A173300-", - "T173301-", - "A173302-", - "T173303-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG047": [ - "P436S" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG109": [ - "F116X", - "*796X" - ] - }, - "labels": { - "aa": "OPG047: P436S; OPG097: K266X, *345X; OPG109: F116X, *796X" - } - }, - "children": [ - { - "name": "NODE_0000017", - "node_attrs": { - "div": 15, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C40251T", - "C63801T", - "T121116-", - "G162243A", - "-196602A", - "-196603A", - "-196604A" - ], - "OPG058": [ - "D62N" - ], - "OPG083": [ - "E306K" - ], - "OPG138": [ - "N6X", - "*191X" - ] - }, - "labels": { - "aa": "OPG058: D62N; OPG083: E306K; OPG138: N6X, *191X" - } - }, - "children": [ - { - "name": "MPXV/021/19", - "node_attrs": { - "div": 17, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2019-04-03" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/021/19" - }, - "strain": { - "value": "OP612680" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C63264T", - "-89100A", - "T104748C", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T187073-" - ], - "OPG109": [ - "X116F", - "X796*" - ], - "OPG123": [ - "D108G" - ] - }, - "labels": { - "aa": "OPG109: X116F, X796*; OPG123: D108G" - } - } - }, - { - "name": "MPXV/046/19", - "node_attrs": { - "div": 18, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2019-05-13" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/046/19" - }, - "strain": { - "value": "OP612684" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C92830T", - "A136516-", - "T136517-", - "C136518-", - "A136519-", - "T136520-", - "C136521-", - "A136522-", - "T136523-", - "C136524-", - "-173302A", - "-173303T", - "G180656A", - "G186423A", - "-196601A" - ], - "OPG113": [ - "S367F" - ], - "OPG153": [ - "D382-", - "D383-", - "D384-" - ], - "OPG209": [ - "D47N" - ], - "OPG210": [ - "E1690K" - ] - }, - "labels": { - "aa": "OPG113: S367F; OPG153: D382-, D383-, D384-; OPG209: D47N; OPG210: E1690K" - } - } - } - ] - }, - { - "name": "NODE_0000018", - "node_attrs": { - "div": 15, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C28164T", - "C87027T", - "G121454A" - ], - "OPG044": [ - "S25F" - ] - }, - "labels": { - "aa": "OPG044: S25F" - } - }, - "children": [ - { - "name": "MPXV/017/19", - "node_attrs": { - "div": 18, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2019-03-19" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/017/19" - }, - "strain": { - "value": "OP612678" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G46685A", - "G144659A", - "G165688A", - "T187073-" - ], - "OPG167": [ - "S250F" - ] - }, - "labels": { - "aa": "OPG167: S250F" - } - } - }, - { - "name": "NODE_0000019", - "node_attrs": { - "div": 17, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G3531A", - "T133078-", - "T133079-", - "T133080-", - "T151621G", - "T179068A" - ], - "OPG178": [ - "F38C" - ] - }, - "labels": { - "aa": "OPG178: F38C" - } - }, - "children": [ - { - "name": "MPXV/007/19", - "node_attrs": { - "div": 18, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2019-02-03" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/007/19" - }, - "strain": { - "value": "OP612675" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T4676C", - "-89100A", - "C193679T" - ], - "OPG109": [ - "X116F", - "X796*" - ] - }, - "labels": { - "aa": "OPG109: X116F, X796*" - } - } - }, - { - "name": "MPXV/013/19", - "node_attrs": { - "div": 17, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2019-02-26" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/013/19" - }, - "strain": { - "value": "OP612676" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A19353-", - "A22434-", - "A138468-", - "A156764-", - "G162952-", - "T172831-", - "C172832-", - "A172833-", - "A172834-", - "A172835-", - "T172836-", - "A172837-", - "A172838-", - "A172839-", - "T172840-", - "A172841-", - "C172842-", - "G172843-", - "C172844-", - "T172845-", - "A172846-", - "T172847-", - "C172848-", - "A172849-", - "T172850-", - "C172851-", - "C172852-", - "G172853-", - "G172854-", - "A172855-", - "T172856-", - "A172857-", - "T172858-", - "A172859-", - "A172860-", - "T179072A" - ], - "OPG155": [ - "F8X", - "*147X" - ], - "OPG188": [ - "G453X", - "*504X" - ] - }, - "labels": { - "aa": "OPG155: F8X, *147X; OPG188: G453X, *504X" - } - } - } - ] - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000020", - "node_attrs": { - "div": 6, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G154015A" - ], - "OPG180": [ - "D442N" - ] - }, - "labels": { - "aa": "OPG180: D442N" - } - }, - "children": [ - { - "name": "MK783032", - "node_attrs": { - "div": 14, - "author": { - "author": "Yinka-Ogunleye,A., Aruna,O., Dalhat,M., Ogoina,D., McCollum,A., Disu,Y., Mamadu,I., Akinpelu,A., Ahmad,A., Burga,J., Ndoreraho,A., Nkunzimana,E., Manneh,L., Mohammed,A., Adeoye,O., Tom-Aba,D., Silenou,B., Ipadeola,O., Saleh,M., Adeyemo,A., Nwadiutor,I., Aworabhi,N., Uke,P., John,D., Wakama,P., Reynolds,M., Mauldin,M., Doty,J., Wilkins,K., Musa,J., Khalakdina,A., Adedeji,A., Mba,N., Ojo,O., Krause,G., Ihekweazu,C., Mauldin,M.R., Li,Y., Gao,J.", - "value": "Yinka-Ogunleye,A., Aruna,O., Dalhat,M., Ogoina,D., McCollum,A., Disu,Y., Mamadu,I., Akinpelu,A., Ahmad,A., Burga,J., Ndoreraho,A., Nkunzimana,E., Manneh,L., Mohammed,A., Adeoye,O., Tom-Aba,D., Silenou,B., Ipadeola,O., Saleh,M., Adeyemo,A., Nwadiutor,I., Aworabhi,N., Uke,P., John,D., Wakama,P., Reynolds,M., Mauldin,M., Doty,J., Wilkins,K., Musa,J., Khalakdina,A., Adedeji,A., Mba,N., Ojo,O., Krause,G., Ihekweazu,C., Mauldin,M.R., Li,Y., Gao,J." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2017-11-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "NCEZID/DHCPP/PRB, Centers for Disease Control & Prevention (US CDC), USA" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MK783032" - }, - "strain": { - "value": "MK783032" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "C10430T", - "C18699T", - "G26002A", - "C134814T", - "C143669T", - "T146862-", - "A146863-", - "T146864-", - "T146865-", - "T146866-", - "T146867-", - "A146868-", - "T146869-", - "A146870-", - "T146871-", - "T146872-", - "T146873-", - "T146874-", - "A146875-", - "T146876-", - "A146877-", - "T146878-", - "T146879-", - "T146880-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "G180039A", - "G180827A", - "G189317A", - "-196602A" - ], - "OPG005": [ - "R40K" - ], - "OPG031": [ - "D44N" - ], - "OPG042": [ - "R366C" - ], - "OPG165": [ - "L52F" - ], - "OPG208": [ - "M258I" - ], - "OPG209": [ - "E104K" - ] - }, - "labels": { - "aa": "OPG005: R40K; OPG031: D44N; OPG042: R366C; OPG165: L52F; OPG208: M258I; OPG209: E104K" - } - } - }, - { - "name": "NODE_0000021", - "node_attrs": { - "div": 21, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T595-", - "C13298T", - "C18792T", - "C30636T", - "C34472T", - "C34578T", - "G80099A", - "G93387A", - "G114659A", - "G124031A", - "A136513-", - "T136514-", - "C136515-", - "A136516-", - "T136517-", - "C136518-", - "A136519-", - "T136520-", - "C136521-", - "C148529-", - "A148530-", - "T148531-", - "A148532-", - "T148533-", - "C148534-", - "A148535-", - "G149265A", - "C149872T", - "C161953T", - "C165782T", - "G168205A", - "C177720T" - ], - "OPG031": [ - "D13N" - ], - "OPG047": [ - "D187N" - ], - "OPG053": [ - "G38E" - ], - "OPG113": [ - "E553K" - ], - "OPG145": [ - "D29N" - ], - "OPG153": [ - "D383-", - "D384-", - "D385-" - ], - "OPG174": [ - "S44L", - "N287X", - "D288-", - "M289-", - "*347X" - ], - "OPG176": [ - "Q22*" - ], - "OPG188": [ - "H120Y" - ], - "OPG190": [ - "P221S" - ], - "OPG205": [ - "R689C" - ] - }, - "labels": { - "aa": "OPG031: D13N; OPG047: D187N; OPG053: G38E; OPG113: E553K; OPG145: D29N; OPG153: D383-, D384-, D385-; OPG174: S44L, N287X, D288-, M289-, *347X; OPG176: Q22*; OPG188: H120Y; OPG190: P221S; OPG205: R689C", - "clade": "A.2" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_VA001", - "node_attrs": { - "div": 43, - "author": { - "author": "Gigante,C.M., Griffin-Thomas,L.A., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Crain,J., Li,Y.", - "value": "Gigante,C.M., Griffin-Thomas,L.A., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Crain,J., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_VA001" - }, - "strain": { - "value": "ON675438" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G11332A", - "G12099A", - "C13648T", - "C15105T", - "C16227T", - "C29887T", - "C42101T", - "G64216A", - "G75614A", - "C117119T", - "C128534T", - "G130454A", - "C134442T", - "C142918T", - "G144446A", - "C156429T", - "C164832T", - "C168532T", - "G174610A", - "A175229-", - "T175230-", - "A175231-", - "T175232-", - "C175233-", - "G175234-", - "T175235-", - "A175236-", - "G175237-", - "T175238-", - "A175239-", - "T175240-", - "C175241-", - "A175242-", - "A175243-", - "G175244-", - "A175245-", - "T175246-", - "G175247-", - "T175248-", - "A175249-", - "A175250-", - "A175251-", - "A175252-", - "T175253-", - "A175254-", - "C175255-", - "T175256-", - "T175257-", - "A175258-", - "C175259-", - "G175260-", - "G175261-", - "T175262-", - "T175263-", - "A175264-", - "T175265-", - "A175266-", - "C175267-", - "C175268-", - "G175269-", - "T175270-", - "C175271-", - "A175272-", - "C175273-", - "A175274-", - "A175275-", - "G175276-", - "A175277-", - "C175278-", - "C175279-", - "A175280-", - "C175281-", - "A175282-", - "G175283-", - "G175284-", - "T175285-", - "T175286-", - "T175287-", - "A175288-", - "A175289-", - "A175290-", - "C175291-", - "T175292-", - "A175293-", - "A175294-", - "T175295-", - "A175296-", - "C175297-", - "T175298-", - "A175299-", - "G175300-", - "A175301-", - "T175302-", - "C175303-", - "C175304-", - "G175305-", - "A175306-", - "A175307-", - "A175308-", - "A175309-", - "T175310-", - "C175311-", - "A175312-", - "A175313-", - "C175314-", - "G175315-", - "T175316-", - "A175317-", - "A175318-", - "C175319-", - "G175320-", - "A175321-", - "T175322-", - "A175323-", - "G175324-", - "G175325-", - "A175326-", - "G175327-", - "A175328-", - "A175329-", - "C175330-", - "C175331-", - "T175332-", - "G175333-", - "C175334-", - "C175335-", - "A175336-", - "A175337-", - "T175338-", - "A175339-", - "T175340-", - "A175341-", - "A175342-", - "C175343-", - "A175344-", - "T175345-", - "G175346-", - "C175347-", - "A175348-", - "G175349-", - "T175350-", - "G175351-", - "C175352-", - "T175353-", - "G175354-", - "T175355-", - "G175356-", - "T175357-", - "C175358-", - "A175359-", - "A175360-", - "C175361-", - "G175362-", - "T175363-", - "C175364-", - "A175365-", - "T175366-", - "T175367-", - "A175368-", - "T175369-", - "T175370-", - "T175371-", - "G175372-", - "T175373-", - "C175374-", - "G175375-", - "A175376-", - "C175377-", - "G175378-", - "A175379-", - "T175380-", - "G175381-", - "T175382-", - "A175383-", - "C175384-", - "T175385-", - "G175386-", - "A175387-", - "T175388-", - "T175389-", - "G175390-", - "A175391-", - "A175392-", - "T175393-", - "G175394-", - "G175395-", - "G175396-", - "A175397-", - "A175398-", - "A175399-", - "A175400-", - "T175401-", - "C175402-", - "C175403-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179628G", - "C179853T", - "G188544A" - ], - "OPG023": [ - "R268*" - ], - "OPG025": [ - "D55N", - "M540I" - ], - "OPG027": [ - "D51N" - ], - "OPG062": [ - "S52L" - ], - "OPG096": [ - "D10N" - ], - "OPG151": [ - "E511K" - ], - "OPG204": [ - "E27K", - "D233X", - "I234-", - "V235-", - "V236-", - "S237-", - "R238-", - "C239-", - "K240-", - "I241-", - "L242-", - "T243-", - "V244-", - "I245-", - "P246-", - "S247-", - "Q248-", - "D249-", - "H250-", - "R251-", - "F252-", - "K253-", - "L254-", - "I255-", - "L256-", - "D257-", - "P258-", - "K259-", - "I260-", - "N261-", - "V262-", - "T263-", - "I264-", - "G265-", - "E266-", - "P267-", - "A268-", - "N269-", - "I270-", - "T271-", - "C272-", - "S273-", - "A274-", - "V275-", - "S276-", - "T277-", - "S278-", - "L279-", - "F280-", - "V281-", - "D282-", - "D283-", - "V284-", - "L285-", - "I286-", - "E287-", - "W288-", - "E289-", - "N290-", - "P291X", - "*352X" - ] - }, - "labels": { - "aa": "OPG023: R268*; OPG025: D55N, M540I; OPG027: D51N; OPG062: S52L; OPG096: D10N; OPG151: E511K; OPG204: E27K, D233X, I234-, V235-, V236-, S237-, R238-, C239-, K240-, I241-, L242-, T243-, V244-, I245-, P246-, S247-, Q248-, D249-, H250-, R251-, F252-, K253-, L254-, I255-, L256-, D257-, P258-, K259-, I260-, N261-, V262-, T263-, I264-, G265-, E266-, P267-, A268-, N269-, I270-, T271-, C272-, S273-, A274-, V275-, S276-, T277-, S278-, L279-, F280-, V281-, D282-, D283-, V284-, L285-, I286-, E287-, W288-, E289-, N290-, P291X, *352X" - } - } - }, - { - "name": "MPXV/111/19", - "node_attrs": { - "div": 22, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2019-12-19" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/111/19" - }, - "strain": { - "value": "OP612689" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "T133078-", - "G144876A", - "A173201-", - "A173202-", - "C173203-", - "G173204-", - "G173205-", - "A173206-", - "C173207-", - "A173208-", - "C173209-", - "C173210-", - "T173211-", - "G173212-", - "G173213-", - "A173214-", - "A173215-", - "T173216-", - "T173217-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG167": [ - "P178S" - ] - }, - "labels": { - "aa": "OPG167: P178S" - } - } - }, - { - "name": "MPXV/113/19", - "node_attrs": { - "div": 21, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2019-12-20" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/113/19" - }, - "strain": { - "value": "OP612690" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "A173300-", - "T173301-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-196602A" - ] - } - } - }, - { - "name": "NODE_0000022", - "node_attrs": { - "div": 36, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.2.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G2752A", - "G39173A", - "C57284T", - "G61844A", - "C74226T", - "G118739A", - "C146223T", - "G148427A", - "G150800A", - "G168365A", - "G170317A", - "G172527A", - "C175759T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "G189417A", - "C189474T", - "C194458T", - "A196603-" - ], - "OPG075": [ - "R72K" - ], - "OPG170": [ - "D186N" - ], - "OPG195": [ - "E46K" - ], - "OPG198": [ - "D94N" - ], - "OPG205": [ - "A35V" - ] - }, - "labels": { - "aa": "OPG075: R72K; OPG170: D186N; OPG195: E46K; OPG198: D94N; OPG205: A35V", - "clade": "A.2.3" - } - }, - "children": [ - { - "name": "MPXV_USA_2021_TX", - "node_attrs": { - "div": 39, - "author": { - "author": "Gigante,C.M., Stringer,J., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Schulte,J., Li,Y.", - "value": "Gigante,C.M., Stringer,J., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Schulte,J., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2021-07-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2021_TX" - }, - "strain": { - "value": "ON676707" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.2.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C100640T", - "G142636A", - "C186104T" - ] - } - } - }, - { - "name": "Monkeypox/PT0428/2022", - "node_attrs": { - "div": 49, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-01" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0428/2022" - }, - "strain": { - "value": "OP555515" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.2.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C30669T", - "C45028T", - "G49377A", - "G95355A", - "C121320T", - "G136132A", - "-136519A", - "-136520T", - "-136521C", - "G142265A", - "C159143T", - "C162264T", - "C170573T", - "C180686T", - "C181216T", - "G188229A", - "A196604-" - ], - "OPG047": [ - "E176K" - ], - "OPG064": [ - "E291K" - ], - "OPG068": [ - "D393N" - ], - "OPG139": [ - "A17T" - ], - "OPG153": [ - "-383D" - ], - "OPG163": [ - "D22N" - ], - "OPG185": [ - "S76F" - ], - "OPG198": [ - "S179L" - ], - "OPG209": [ - "Q57*" - ] - }, - "labels": { - "aa": "OPG047: E176K; OPG064: E291K; OPG068: D393N; OPG139: A17T; OPG153: -383D; OPG163: D22N; OPG185: S76F; OPG198: S179L; OPG209: Q57*" - } - } - } - ] - }, - { - "name": "NODE_0000023", - "node_attrs": { - "div": 41, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.2.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G11948A", - "C14790T", - "G21991A", - "G23118A", - "G38923A", - "G39515A", - "G56546A", - "G57786A", - "G93312A", - "C103019T", - "C112470T", - "C124129T", - "C127906T", - "G135303A", - "A136522-", - "T136523-", - "C136524-", - "G145902A", - "C149365T", - "G155611A", - "G158424A", - "G162640A", - "G186984A", - "A196603-", - "A196604-" - ], - "OPG023": [ - "S318F" - ], - "OPG025": [ - "D160N" - ], - "OPG037": [ - "S148L" - ], - "OPG056": [ - "R38C" - ], - "OPG113": [ - "V528I" - ], - "OPG122": [ - "H198Y" - ], - "OPG132": [ - "M357I" - ], - "OPG150": [ - "S43L" - ], - "OPG153": [ - "D382-" - ], - "OPG174": [ - "G11R" - ], - "OPG188": [ - "G349S" - ], - "OPG210": [ - "D1877N" - ] - }, - "labels": { - "aa": "OPG023: S318F; OPG025: D160N; OPG037: S148L; OPG056: R38C; OPG113: V528I; OPG122: H198Y; OPG132: M357I; OPG150: S43L; OPG153: D382-; OPG174: G11R; OPG188: G349S; OPG210: D1877N", - "clade": "A.2.2" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_PA0016", - "node_attrs": { - "div": 48, - "author": { - "author": "Gigante,C.M., Xia,D., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Plipat,N., Li,Y.", - "value": "Gigante,C.M., Xia,D., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Plipat,N., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_PA0016" - }, - "strain": { - "value": "OP450997" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.2.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G451A", - "G20576A", - "C20581T", - "G67351A", - "G78259A", - "G94479A", - "C133402T", - "C176148T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "C196759T" - ], - "OPG036": [ - "E162K" - ], - "OPG085": [ - "S394F" - ], - "OPG205": [ - "H165Y" - ] - }, - "labels": { - "aa": "OPG036: E162K; OPG085: S394F; OPG205: H165Y" - } - } - }, - { - "name": "NODE_0000024", - "node_attrs": { - "div": 46, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.2.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C13686T", - "C21861T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G151112A", - "G174721A", - "C188491T" - ], - "OPG025": [ - "E528K" - ], - "OPG037": [ - "M191I" - ], - "OPG204": [ - "A64T" - ] - }, - "labels": { - "aa": "OPG025: E528K; OPG037: M191I; OPG204: A64T" - } - }, - "children": [ - { - "name": "MPXV_UK_2022_9000166", - "node_attrs": { - "div": 50, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-06-29" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000166" - }, - "strain": { - "value": "OP331336" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.2.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C27826T", - "G59282A", - "C65743A", - "G85356A" - ], - "OPG043": [ - "E44K" - ], - "OPG084": [ - "P341H" - ], - "OPG106": [ - "S48F" - ] - }, - "labels": { - "aa": "OPG043: E44K; OPG084: P341H; OPG106: S48F" - } - } - }, - { - "name": "hMPXV/Austria/MUW1607960/2023", - "node_attrs": { - "div": 56, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "country": { - "value": "Austria" - }, - "date": { - "value": "2023-04-05" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1607960/2023" - }, - "strain": { - "value": "OR113690" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.2.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C18102T", - "C52429T", - "C86957T", - "G97318A", - "C121394T", - "G129982A", - "G146714A", - "C148895A", - "G165892A", - "G175471A" - ], - "OPG031": [ - "D243N" - ], - "OPG108": [ - "D35N" - ], - "OPG117": [ - "D424N" - ], - "OPG170": [ - "A22V" - ], - "OPG174": [ - "M167I" - ], - "OPG204": [ - "E314K" - ] - }, - "labels": { - "aa": "OPG031: D243N; OPG108: D35N; OPG117: D424N; OPG170: A22V; OPG174: M167I; OPG204: E314K" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000025", - "node_attrs": { - "div": 22, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C25072T", - "A136522-", - "T136523-", - "C136524-" - ], - "OPG040": [ - "R136Q" - ], - "OPG153": [ - "D382-" - ] - }, - "labels": { - "aa": "OPG040: R136Q; OPG153: D382-" - } - }, - "children": [ - { - "name": "MPXV/191/20", - "node_attrs": { - "div": 24, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2020-01-23" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/191/20" - }, - "strain": { - "value": "OP612691" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "C90329T", - "C132520T", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "A196603-", - "A196604-" - ], - "OPG111": [ - "S22L" - ] - }, - "labels": { - "aa": "OPG111: S22L" - } - } - }, - { - "name": "NODE_0000026", - "node_attrs": { - "div": 35, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.2.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G36898A", - "G42183A", - "C42903T", - "G50346A", - "C54268T", - "C73616T", - "G79406A", - "G105746A", - "T133078-", - "T133079-", - "A140492C", - "C142498T", - "C157737T", - "C161152T", - "C169722-", - "A169723-", - "G169724-", - "A169725-", - "T169726-", - "A169727-", - "C169728-", - "A169729-", - "G169730-", - "A169731-", - "T169732-", - "A169733-", - "G174519-", - "A174520-", - "T174521-", - "G174522-", - "A174523-", - "A174524-", - "C179537T" - ], - "OPG062": [ - "M79I" - ], - "OPG063": [ - "M262I" - ], - "OPG069": [ - "D121N" - ], - "OPG102": [ - "D108N" - ], - "OPG160": [ - "S195A" - ], - "OPG197": [ - "S18X", - "D19-", - "T20-", - "D21-", - "T22X", - "*101X" - ], - "OPG208": [ - "S91L" - ] - }, - "labels": { - "aa": "OPG062: M79I; OPG063: M262I; OPG069: D121N; OPG102: D108N; OPG160: S195A; OPG197: S18X, D19-, T20-, D21-, T22X, *101X; OPG208: S91L", - "clade": "A.2.1" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_FL001", - "node_attrs": { - "div": 38, - "author": { - "author": "Gigante,C.M., Lee,P., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Mendoza,R., Li,Y.", - "value": "Gigante,C.M., Lee,P., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Mendoza,R., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_FL001" - }, - "strain": { - "value": "ON674051" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.2.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T95936A", - "C112544T", - "G163540A" - ], - "OPG116": [ - "D192E" - ], - "OPG132": [ - "D333N" - ], - "OPG189": [ - "E70K" - ] - }, - "labels": { - "aa": "OPG116: D192E; OPG132: D333N; OPG189: E70K" - } - } - }, - { - "name": "NODE_0000027", - "node_attrs": { - "div": 36, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.2.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C184924T" - ], - "OPG210": [ - "S1190L" - ] - }, - "labels": { - "aa": "OPG210: S1190L" - } - }, - "children": [ - { - "name": "Mpox-HCMC-M157", - "node_attrs": { - "div": 48, - "author": { - "author": "Nguyen,D.T., Le,H.M., Huynh,H.T.T., Tang,T.C., Le,N.H., Nguyen,H.H., Nghiem,N.M., Nguyen,H.T.T., Vo,Q.T., Vu,T.T.K., Nguyen,T.T., Phan,T.V., Nguyen,T.L.N., Le,T.M., Vo,Q.M., Dinh,M.N.H., Nguyen,P.T., Tran,P.T.L., Tran,T.T.T., Pham,T.T.N., Nguyen,T.H., Truong,L.T.T., Nguyen,H.N.T., Tran,T.T., Le,K.T.T., Lam,Y.M., Thwaites,G., Thwaites,L., Nguyen,C.V.V., Nguyen,A.T., Le,T.V.", - "value": "Nguyen,D.T., Le,H.M., Huynh,H.T.T., Tang,T.C., Le,N.H., Nguyen,H.H., Nghiem,N.M., Nguyen,H.T.T., Vo,Q.T., Vu,T.T.K., Nguyen,T.T., Phan,T.V., Nguyen,T.L.N., Le,T.M., Vo,Q.M., Dinh,M.N.H., Nguyen,P.T., Tran,P.T.L., Tran,T.T.T., Pham,T.T.N., Nguyen,T.H., Truong,L.T.T., Nguyen,H.N.T., Tran,T.T., Le,K.T.T., Lam,Y.M., Thwaites,G., Thwaites,L., Nguyen,C.V.V., Nguyen,A.T., Le,T.V." - }, - "country": { - "value": "Vietnam" - }, - "date": { - "value": "2022-09-26" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "EI group, Oxford University Clinica Research Unit" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Mpox-HCMC-M157" - }, - "strain": { - "value": "OP936000" - }, - "lineage": { - "value": "A.2.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A271-", - "C272-", - "C32252T", - "G51559A", - "A86823T", - "G103706A", - "T133080-", - "T133081-", - "T133082-", - "C152033T", - "T167015G", - "T167017-", - "C167019A", - "A167020T", - "A167021C", - "C167022T", - "G167029C", - "A179030-", - "A179031-", - "T179032-", - "A179033-", - "C179034-", - "G179035-", - "G179036-", - "A179037-", - "G179038-", - "T179039-", - "A179040-", - "C179041-", - "A179042-", - "A179043-", - "A179044-", - "C179045-", - "A179046-", - "T179047-", - "A187574C" - ], - "OPG192": [ - "I96X", - "Q97I", - "R98C", - "G100A", - "*183X" - ] - }, - "labels": { - "aa": "OPG192: I96X, Q97I, R98C, G100A, *183X" - } - } - }, - { - "name": "NODE_0000028", - "node_attrs": { - "div": 39, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.2.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G30868A", - "G43103A", - "G102599A", - "A136525-", - "T136526-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-169722C", - "-169723A", - "-169724G", - "-169725A", - "-169726T", - "-169727A", - "-169728C", - "-169729A", - "-169730G", - "-169731A", - "-169732T", - "-169733A", - "T196595-", - "T196596-", - "T196597-", - "-196601A", - "-196602A" - ], - "OPG063": [ - "P196S" - ], - "OPG122": [ - "D58N" - ], - "OPG153": [ - "D381X", - "*510X" - ], - "OPG197": [ - "X18S", - "-19D", - "-20T", - "-21D", - "X22T", - "X101*" - ] - }, - "labels": { - "aa": "OPG063: P196S; OPG122: D58N; OPG153: D381X, *510X; OPG197: X18S, -19D, -20T, -21D, X22T, X101*" - } - }, - "children": [ - { - "name": "MPXV_UK_2022_9000155", - "node_attrs": { - "div": 40, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-06-03" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000155" - }, - "strain": { - "value": "OP331335" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.2.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T595-", - "-133078T", - "-133079T", - "-136513A", - "-136514T", - "-136515C", - "-136516A", - "-136517T", - "-136518C", - "-136519A", - "-136520T", - "-136521C", - "-136522A", - "-136523T", - "-136524C", - "-136525A", - "-136526T", - "C164210T", - "-174519G", - "-174520A", - "-174521T", - "-174522G", - "-174523A", - "-174524A", - "-196595T", - "-196596T", - "-196597T" - ], - "OPG153": [ - "X381D", - "-382D", - "-383D", - "-384D", - "-385D", - "X510*" - ], - "OPG189": [ - "S293L" - ] - }, - "labels": { - "aa": "OPG153: X381D, -382D, -383D, -384D, -385D, X510*; OPG189: S293L" - } - } - }, - { - "name": "Slovenia-MPXV-30-2022", - "node_attrs": { - "div": 39, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "country": { - "value": "Slovenia" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Slovenia-MPXV-30-2022" - }, - "strain": { - "value": "OP605572" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.2.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C131-", - "-594T", - "C136527-" - ], - "OPG153": [ - "X381-", - "X510*" - ] - }, - "labels": { - "aa": "OPG153: X381-, X510*" - } - } - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000051", - "node_attrs": { - "div": 6, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "C187428T" - ] - } - }, - "children": [ - { - "name": "NODE_0000009", - "node_attrs": { - "div": 14, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G56968A", - "G61844A", - "C84008T", - "G96841A", - "C100971T", - "C134078T", - "C151050T", - "C169722-", - "A169723-", - "G169724-", - "A169725-", - "T169726-", - "A169727-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "G188889-" - ], - "OPG074": [ - "S53L" - ], - "OPG117": [ - "D265N" - ], - "OPG120": [ - "E260K" - ], - "OPG197": [ - "S18X", - "D19-", - "T20X", - "*101X" - ] - }, - "labels": { - "aa": "OPG074: S53L; OPG117: D265N; OPG120: E260K; OPG197: S18X, D19-, T20X, *101X", - "clade": "A.3" - } - }, - "children": [ - { - "name": "MPXV_Nig_2017_297957", - "node_attrs": { - "div": 29, - "author": { - "author": "Faye,O., Pratt,C.B., Faye,M., Fall,G., Chitty,J.A., Diagne,M.M., Wiley,M.R., Yinka-Ogunleye,A.F., Aruna,S., Etebu,E.N., Aworabhi,N., Ogoina,D., Numbere,W., Mba,N., Palacios,G., Sall,A.A., Ihekweazu,C., Diagne,M., Palacios,G.F., Sall,A.", - "value": "Faye,O., Pratt,C.B., Faye,M., Fall,G., Chitty,J.A., Diagne,M.M., Wiley,M.R., Yinka-Ogunleye,A.F., Aruna,S., Etebu,E.N., Aworabhi,N., Ogoina,D., Numbere,W., Mba,N., Palacios,G., Sall,A.A., Ihekweazu,C., Diagne,M., Palacios,G.F., Sall,A." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2017-XX-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "USAMRIID, Center for Genome Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_Nig_2017_297957" - }, - "strain": { - "value": "MG693723" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A8143-", - "G8144-", - "C8145-", - "A8146-", - "T8147-", - "A8148-", - "T8149-", - "T8150-", - "A8151-", - "A8152-", - "A8153-", - "G8154-", - "T8155-", - "A8156-", - "A8157-", - "A8158-", - "A8159-", - "T8160-", - "C8161-", - "T8162-", - "A8163-", - "G8164-", - "T8165-", - "T8166-", - "A8167-", - "C8168-", - "C8169-", - "T8170-", - "T8171-", - "G8172-", - "A8173-", - "A8174-", - "A8175-", - "A8176-", - "T8177-", - "G8178-", - "A8179-", - "A8180-", - "T8181-", - "A8182-", - "C8183-", - "A8184-", - "G8185-", - "T8186-", - "G8187-", - "G8188-", - "G8189-", - "T8190-", - "G8191-", - "G8192-", - "T8193-", - "T8194-", - "C8195-", - "C8196-", - "G8197-", - "T8198-", - "A8199-", - "T8200-", - "C8201-", - "A8202-", - "C8203-", - "C8204-", - "A8205-", - "G8206-", - "T8207-", - "A8208-", - "A8209-", - "G8210-", - "A8211-", - "A8212-", - "C8213-", - "A8214-", - "T8215-", - "A8216-", - "A8217-", - "T8218-", - "A8219-", - "G8220-", - "T8221-", - "C8222-", - "G8223-", - "A8224-", - "A8225-", - "T8226-", - "A8227-", - "C8228-", - "A8229-", - "G8230-", - "T8231-", - "A8232-", - "T8233-", - "C8234-", - "C8235-", - "G8236-", - "A8237-", - "T8238-", - "T8239-", - "G8240-", - "A8241-", - "G8242-", - "A8243-", - "T8244-", - "T8245-", - "T8246-", - "T8247-", - "G8248-", - "C8249-", - "A8250-", - "T8251-", - "A8252-", - "C8253-", - "A8254-", - "A8255-", - "T8256-", - "A8257-", - "C8258-", - "T8259-", - "A8260-", - "G8261-", - "T8262-", - "C8263-", - "T8264-", - "A8265-", - "G8266-", - "A8267-", - "A8268-", - "A8269-", - "G8270-", - "A8271-", - "A8272-", - "A8273-", - "T8274-", - "T8275-", - "T8276-", - "G8277-", - "T8278-", - "A8279-", - "A8280-", - "T8281-", - "C8282-", - "A8283-", - "T8284-", - "C8285-", - "C8286-", - "T8287-", - "C8288-", - "T8289-", - "G8290-", - "T8291-", - "G8292-", - "A8293-", - "C8294-", - "A8295-", - "G8296-", - "G8297-", - "A8298-", - "G8299-", - "T8300-", - "C8301-", - "C8302-", - "A8303-", - "T8304-", - "A8305-", - "T8306-", - "A8307-", - "T8308-", - "C8309-", - "T8310-", - "G8311-", - "T8312-", - "A8313-", - "T8314-", - "C8315-", - "A8316-", - "T8317-", - "C8318-", - "G8319-", - "T8320-", - "C8321-", - "T8322-", - "A8323-", - "G8324-", - "T8325-", - "T8326-", - "T8327-", - "T8328-", - "T8329-", - "A8330-", - "T8331-", - "C8332-", - "A8333-", - "G8334-", - "T8335-", - "G8336-", - "T8337-", - "C8338-", - "C8339-", - "T8340-", - "A8341-", - "T8342-", - "G8343-", - "C8344-", - "T8345-", - "A8346-", - "T8347-", - "A8348-", - "T8349-", - "T8350-", - "C8351-", - "C8352-", - "T8353-", - "G8354-", - "T8355-", - "T8356-", - "A8357-", - "T8358-", - "C8359-", - "A8360-", - "T8361-", - "C8362-", - "A8363-", - "T8364-", - "T8365-", - "A8366-", - "G8367-", - "T8368-", - "T8369-", - "A8370-", - "A8371-", - "T8372-", - "G8373-", - "A8374-", - "A8375-", - "A8376-", - "A8377-", - "T8378-", - "A8379-", - "A8380-", - "C8381-", - "T8382-", - "C8383-", - "T8384-", - "C8385-", - "G8386-", - "T8387-", - "G8388-", - "C8389-", - "T8390-", - "T8391-", - "C8392-", - "A8393-", - "G8394-", - "A8395-", - "A8396-", - "A8397-", - "A8398-", - "G8399-", - "T8400-", - "C8401-", - "A8402-", - "A8403-", - "A8404-", - "T8405-", - "A8406-", - "T8407-", - "T8408-", - "G8409-", - "T8410-", - "A8411-", - "T8412-", - "C8413-", - "C8414-", - "A8415-", - "T8416-", - "A8417-", - "C8418-", - "A8419-", - "T8420-", - "A8421-", - "T8422-", - "A8423-", - "T8424-", - "C8425-", - "T8426-", - "C8427-", - "C8428-", - "A8429-", - "A8430-", - "A8431-", - "A8432-", - "C8433-", - "T8434-", - "A8435-", - "T8436-", - "C8437-", - "A8438-", - "C8439-", - "T8440-", - "T8441-", - "A8442-", - "T8443-", - "A8444-", - "C8445-", - "G8446-", - "T8447-", - "T8448-", - "T8449-", - "A8450-", - "T8451-", - "C8452-", - "T8453-", - "T8454-", - "T8455-", - "A8456-", - "A8457-", - "C8458-", - "G8459-", - "A8460-", - "A8461-", - "C8462-", - "A8463-", - "T8464-", - "A8465-", - "T8466-", - "A8467-", - "C8468-", - "C8469-", - "T8470-", - "A8471-", - "G8472-", - "A8473-", - "T8474-", - "G8475-", - "G8476-", - "T8477-", - "T8478-", - "A8479-", - "T8480-", - "T8481-", - "T8482-", - "A8483-", - "C8484-", - "T8485-", - "A8486-", - "A8487-", - "C8488-", - "A8489-", - "G8490-", - "A8491-", - "C8492-", - "A8493-", - "T8494-", - "T8495-", - "T8496-", - "T8497-", - "T8498-", - "T8499-", - "C8500-", - "A8501-", - "A8502-", - "G8503-", - "A8504-", - "T8505-", - "C8506-", - "T8507-", - "A8508-", - "T8509-", - "T8510-", - "G8511-", - "A8512-", - "C8513-", - "A8514-", - "A8515-", - "T8516-", - "A8517-", - "A8518-", - "C8519-", - "T8520-", - "C8521-", - "C8522-", - "T8523-", - "A8524-", - "T8525-", - "A8526-", - "G8527-", - "T8528-", - "T8529-", - "T8530-", - "C8531-", - "C8532-", - "A8533-", - "C8534-", - "A8535-", - "T8536-", - "C8537-", - "A8538-", - "A8539-", - "C8540-", - "C8541-", - "A8542-", - "A8543-", - "G8544-", - "T8545-", - "A8546-", - "A8547-", - "T8548-", - "G8549-", - "A8550-", - "T8551-", - "C8552-", - "A8553-", - "T8554-", - "C8555-", - "T8556-", - "A8557-", - "T8558-", - "T8559-", - "G8560-", - "T8561-", - "T8562-", - "A8563-", - "T8564-", - "A8565-", - "T8566-", - "A8567-", - "A8568-", - "C8569-", - "A8570-", - "A8571-", - "T8572-", - "A8573-", - "A8574-", - "C8575-", - "A8576-", - "T8577-", - "A8578-", - "A8579-", - "C8580-", - "T8581-", - "C8582-", - "T8583-", - "T8584-", - "T8585-", - "T8586-", - "C8587-", - "C8588-", - "A8589-", - "T8590-", - "T8591-", - "T8592-", - "T8593-", - "T8594-", - "A8595-", - "T8596-", - "C8597-", - "A8598-", - "G8599-", - "T8600-", - "A8601-", - "T8602-", - "C8603-", - "T8604-", - "A8605-", - "T8606-", - "A8607-", - "T8608-", - "C8609-", - "A8610-", - "A8611-", - "C8612-", - "G8613-", - "T8614-", - "C8615-", - "G8616-", - "T8617-", - "T8618-", - "G8619-", - "T8620-", - "A8621-", - "G8622-", - "T8623-", - "G8624-", - "A8625-", - "A8626-", - "T8627-", - "A8628-", - "G8629-", - "T8630-", - "A8631-", - "G8632-", - "T8633-", - "C8634-", - "A8635-", - "T8636-", - "T8637-", - "G8638-", - "A8639-", - "T8640-", - "C8641-", - "T8642-", - "A8643-", - "T8644-", - "T8645-", - "A8646-", - "T8647-", - "A8648-", - "T8649-", - "G8650-", - "A8651-", - "A8652-", - "A8653-", - "C8654-", - "G8655-", - "G8656-", - "A8657-", - "T8658-", - "A8659-", - "T8660-", - "G8661-", - "T8662-", - "C8663-", - "T8664-", - "A8665-", - "G8666-", - "T8667-", - "T8668-", - "A8669-", - "A8670-", - "T8671-", - "A8672-", - "T8673-", - "T8674-", - "T8675-", - "T8676-", - "C8677-", - "T8678-", - "T8679-", - "T8680-", - "G8681-", - "A8682-", - "T8683-", - "T8684-", - "T8685-", - "A8686-", - "A8687-", - "A8688-", - "G8689-", - "T8690-", - "C8691-", - "T8692-", - "A8693-", - "T8694-", - "A8695-", - "G8696-", - "T8697-", - "C8698-", - "T8699-", - "T8700-", - "T8701-", - "A8702-", - "C8703-", - "A8704-", - "A8705-", - "A8706-", - "C8707-", - "A8708-", - "T8709-", - "A8710-", - "A8711-", - "T8712-", - "A8713-", - "T8714-", - "C8715-", - "C8716-", - "T8717-", - "T8718-", - "A8719-", - "T8720-", - "C8721-", - "C8722-", - "G8723-", - "A8724-", - "C8725-", - "T8726-", - "T8727-", - "T8728-", - "A8729-", - "T8730-", - "A8731-", - "T8732-", - "T8733-", - "T8734-", - "C8735-", - "C8736-", - "T8737-", - "G8738-", - "T8739-", - "A8740-", - "G8741-", - "G8742-", - "G8743-", - "T8744-", - "G8745-", - "G8746-", - "C8747-", - "A8748-", - "T8749-", - "A8750-", - "A8751-", - "T8752-", - "T8753-", - "T8754-", - "T8755-", - "A8756-", - "T8757-", - "T8758-", - "C8759-", - "T8760-", - "G8761-", - "C8762-", - "C8763-", - "T8764-", - "C8765-", - "C8766-", - "A8767-", - "C8768-", - "A8769-", - "A8770-", - "T8771-", - "C8772-", - "A8773-", - "G8774-", - "T8775-", - "G8776-", - "T8777-", - "T8778-", - "T8779-", - "C8780-", - "C8781-", - "A8782-", - "A8783-", - "A8784-", - "T8785-", - "A8786-", - "T8787-", - "A8788-", - "T8789-", - "T8790-", - "A8791-", - "C8792-", - "T8793-", - "A8794-", - "G8795-", - "A8796-", - "C8797-", - "A8798-", - "A8799-", - "T8800-", - "A8801-", - "T8802-", - "T8803-", - "C8804-", - "C8805-", - "A8806-", - "T8807-", - "A8808-", - "T8809-", - "A8810-", - "G8811-", - "T8812-", - "T8813-", - "A8814-", - "T8815-", - "T8816-", - "A8817-", - "G8818-", - "T8819-", - "T8820-", - "A8821-", - "A8822-", - "G8823-", - "G8824-", - "G8825-", - "A8826-", - "C8827-", - "C8828-", - "C8829-", - "A8830-", - "A8831-", - "T8832-", - "T8833-", - "A8834-", - "G8835-", - "A8836-", - "A8837-", - "C8838-", - "A8839-", - "C8840-", - "G8841-", - "T8842-", - "A8843-", - "C8844-", - "G8845-", - "C8846-", - "G8847-", - "C8848-", - "T8849-", - "T8850-", - "A8851-", - "T8852-", - "T8853-", - "C8854-", - "A8855-", - "T8856-", - "C8857-", - "A8858-", - "T8859-", - "T8860-", - "T8861-", - "G8862-", - "G8863-", - "A8864-", - "T8865-", - "C8866-", - "G8867-", - "T8868-", - "A8869-", - "T8870-", - "T8871-", - "T8872-", - "C8873-", - "A8874-", - "T8875-", - "A8876-", - "A8877-", - "A8878-", - "A8879-", - "G8880-", - "T8881-", - "T8882-", - "A8883-", - "T8884-", - "T8885-", - "A8886-", - "T8887-", - "G8888-", - "T8889-", - "T8890-", - "A8891-", - "T8892-", - "A8893-", - "G8894-", - "A8895-", - "T8896-", - "G8897-", - "T8898-", - "C8899-", - "A8900-", - "A8901-", - "C8902-", - "A8903-", - "C8904-", - "A8905-", - "T8906-", - "T8907-", - "C8908-", - "T8909-", - "A8910-", - "C8911-", - "A8912-", - "T8913-", - "T8914-", - "T8915-", - "T8916-", - "T8917-", - "T8918-", - "T8919-", - "A8920-", - "A8921-", - "T8922-", - "T8923-", - "G8924-", - "T8925-", - "C8926-", - "T8927-", - "A8928-", - "T8929-", - "A8930-", - "T8931-", - "A8932-", - "G8933-", - "T8934-", - "A8935-", - "T8936-", - "T8937-", - "T8938-", - "T8939-", - "T8940-", - "C8941-", - "T8942-", - "G8943-", - "A8944-", - "T8945-", - "A8946-", - "T8947-", - "T8948-", - "T8949-", - "T8950-", - "C8951-", - "T8952-", - "A8953-", - "T8954-", - "A8955-", - "A8956-", - "T8957-", - "A8958-", - "T8959-", - "C8960-", - "A8961-", - "G8962-", - "A8963-", - "A8964-", - "T8965-", - "T8966-", - "G8967-", - "T8968-", - "C8969-", - "T8970-", - "T8971-", - "C8972-", - "C8973-", - "A8974-", - "T8975-", - "A8976-", - "G8977-", - "G8978-", - "A8979-", - "A8980-", - "G8981-", - "T8982-", - "T8983-", - "G8984-", - "T8985-", - "A8986-", - "T8987-", - "A8988-", - "C8989-", - "T8990-", - "A8991-", - "T8992-", - "T8993-", - "C8994-", - "G8995-", - "G8996-", - "A8997-", - "A8998-", - "T8999-", - "C9000-", - "A9001-", - "G9002-", - "T9003-", - "T9004-", - "A9005-", - "C9006-", - "A9007-", - "T9008-", - "G9009-", - "T9010-", - "T9011-", - "T9012-", - "A9013-", - "A9014-", - "A9015-", - "T9016-", - "A9017-", - "A9018-", - "T9019-", - "T9020-", - "C9021-", - "T9022-", - "C9023-", - "T9024-", - "G9025-", - "A9026-", - "T9027-", - "G9028-", - "T9029-", - "C9030-", - "A9031-", - "T9032-", - "T9033-", - "C9034-", - "C9035-", - "T9036-", - "T9037-", - "A9038-", - "T9039-", - "A9040-", - "C9041-", - "A9042-", - "A9043-", - "T9044-", - "C9045-", - "A9046-", - "A9047-", - "A9048-", - "T9049-", - "T9050-", - "C9051-", - "A9052-", - "T9053-", - "T9054-", - "A9055-", - "T9056-", - "T9057-", - "A9058-", - "A9059-", - "A9060-", - "C9061-", - "A9062-", - "G9063-", - "T9064-", - "T9065-", - "T9066-", - "A9067-", - "A9068-", - "T9069-", - "A9070-", - "G9071-", - "T9072-", - "C9073-", - "T9074-", - "G9075-", - "T9076-", - "A9077-", - "G9078-", - "A9079-", - "C9080-", - "C9081-", - "T9082-", - "T9083-", - "T9084-", - "A9085-", - "T9086-", - "C9087-", - "G9088-", - "T9089-", - "C9090-", - "G9091-", - "T9092-", - "A9093-", - "C9094-", - "A9095-", - "T9096-", - "A9097-", - "T9098-", - "C9099-", - "C9100-", - "A9101-", - "T9102-", - "T9103-", - "G9104-", - "T9105-", - "C9106-", - "T9107-", - "T9108-", - "A9109-", - "T9110-", - "T9111-", - "A9112-", - "G9113-", - "T9114-", - "T9115-", - "A9116-", - "C9117-", - "G9118-", - "C9119-", - "T9120-", - "T9121-", - "A9122-", - "T9123-", - "T9124-", - "T9125-", - "T9126-", - "T9127-", - "A9128-", - "T9129-", - "G9130-", - "G9131-", - "G9132-", - "T9133-", - "T9134-", - "T9135-", - "T9136-", - "A9137-", - "C9138-", - "G9139-", - "T9140-", - "T9141-", - "G9142-", - "C9143-", - "T9144-", - "T9145-", - "T9146-", - "A9147-", - "T9148-", - "T9149-", - "A9150-", - "T9151-", - "A9152-", - "T9153-", - "T9154-", - "T9155-", - "T9156-", - "A9157-", - "T9158-", - "A9159-", - "A9160-", - "T9161-", - "A9162-", - "A9163-", - "T9164-", - "G9165-", - "A9166-", - "T9167-", - "T9168-", - "G9169-", - "T9170-", - "T9171-", - "T9172-", - "G9173-", - "A9174-", - "C9175-", - "A9176-", - "A9177-", - "T9178-", - "G9179-", - "T9180-", - "C9181-", - "G9182-", - "T9183-", - "A9184-", - "G9185-", - "T9186-", - "A9187-", - "T9188-", - "A9189-", - "G9190-", - "A9191-", - "T9192-", - "A9193-", - "T9194-", - "A9195-", - "T9196-", - "T9197-", - "A9198-", - "T9199-", - "T9200-", - "A9201-", - "G9202-", - "A9203-", - "G9204-", - "G9205-", - "A9206-", - "G9207-", - "G9208-", - "T9209-", - "A9210-", - "T9211-", - "A9212-", - "A9213-", - "T9214-", - "T9215-", - "A9216-", - "T9217-", - "A9218-", - "A9219-", - "A9220-", - "A9221-", - "A9222-", - "G9223-", - "T9224-", - "T9225-", - "T9226-", - "C9227-", - "T9228-", - "G9229-", - "A9230-", - "G9231-", - "T9232-", - "A9233-", - "C9234-", - "G9235-", - "A9236-", - "T9237-", - "G9238-", - "T9239-", - "T9240-", - "A9241-", - "T9242-", - "A9243-", - "A9244-", - "G9245-", - "A9246-", - "G9247-", - "G9248-", - "A9249-", - "G9250-", - "A9251-", - "G9252-", - "G9253-", - "A9254-", - "C9255-", - "A9256-", - "C9257-", - "A9258-", - "T9259-", - "T9260-", - "A9261-", - "A9262-", - "C9263-", - "A9264-", - "T9265-", - "C53702T", - "A166846-", - "T166847-", - "A166848-", - "A166849-", - "T166850-", - "A166851-", - "T166852-", - "A166853-", - "G166854-", - "A166855-", - "A166856-", - "A166857-", - "A166858-", - "T166859-", - "T166860-", - "C166861-", - "A166862-", - "T166863-", - "A166864-", - "T166865-", - "A166866-", - "C166867-", - "T166868-", - "G166869-", - "A166870-", - "T166871-", - "G166872-", - "A166873-", - "T166874-", - "A166875-", - "A166876-", - "T166877-", - "A166878-", - "A166879-", - "T166880-", - "G166881-", - "A166882-", - "A166883-", - "T166884-", - "T166885-", - "G166886-", - "G166887-", - "T166888-", - "G166889-", - "T166890-", - "T166891-", - "A166892-", - "A166893-", - "A166894-", - "T166895-", - "T166896-", - "T166897-", - "T166898-", - "A166899-", - "A166900-", - "A166901-", - "G166902-", - "A166903-", - "G166904-", - "T166905-", - "A166906-", - "C166907-", - "A166908-", - "C166909-", - "A166910-", - "A166911-", - "T166912-", - "T166913-", - "T166914-", - "C166915-", - "T166916-", - "A166917-", - "T166918-", - "T166919-", - "A166920-", - "T166921-", - "T166922-", - "A166923-", - "C166924-", - "A166925-", - "G166926-", - "A166927-", - "G166928-", - "T166929-", - "C166930-", - "A166931-", - "T166932-", - "G166933-", - "T166934-", - "G166935-", - "A166936-", - "C166937-", - "G166938-", - "T166939-", - "C166940-", - "G166941-", - "G166942-", - "A166943-", - "T166944-", - "T166945-", - "T166946-", - "G166947-", - "A166948-", - "T166949-", - "T166950-", - "C166951-", - "C166952-", - "A166953-", - "T166954-", - "A166955-", - "G166956-", - "A166957-", - "T166958-", - "A166959-", - "T166960-", - "A166961-", - "G166962-", - "A166963-", - "T166964-", - "G166965-", - "T166966-", - "T166967-", - "A166968-", - "T166969-", - "A166970-", - "A166971-", - "A166972-", - "C166973-", - "G166974-", - "A166975-", - "C166976-", - "T166977-", - "A166978-", - "T166979-", - "C168582A", - "C168584-", - "T168585-", - "C168586-", - "T168587-", - "G168588-", - "T168589-", - "A168590-", - "T168591-", - "T168592-", - "T168593-", - "C168594-", - "T168595-", - "G168596-", - "T168597-", - "A168598-", - "T168599-", - "A168600-", - "T168601-", - "T168602-", - "G168603-", - "T168604-", - "G168605-", - "A168606-", - "T168607-", - "C168608-", - "A168609-", - "G168611C", - "G168614-", - "C168615-", - "G168616-", - "G168617-", - "G168618-", - "A168619-", - "G168620-", - "A168621-", - "C168622-", - "A168623-", - "T168624-", - "A168625-", - "A168626-", - "A168627-", - "A168628-", - "T168629-", - "T168630-", - "T168631-", - "G168632-", - "A168633-", - "G168634-", - "G168635-", - "A168636-", - "G168637-", - "T168638-", - "A168639-", - "T168640-", - "A168641-", - "C168642-", - "T168643-", - "C168644-", - "A168645-", - "A168646-", - "G168647-", - "A168648-", - "A168649-", - "T168650-", - "C168651-", - "A168652-", - "A168653-", - "G168654-", - "T168655-", - "G168656-", - "A168657-", - "T168658-", - "A168659-", - "T168660-", - "C168661-", - "A168662-", - "G168663-", - "T168664-", - "A168665-", - "T168666-", - "T168667-", - "A168674C", - "A168675T", - "T168677-", - "A168678-", - "T168679-", - "G168680-", - "A168681-", - "T168682-", - "T168683-", - "C168684-", - "A168685-", - "T168686-", - "C168687-", - "A168688-", - "T168689-", - "G168690-", - "T168691-", - "A168692-", - "T168693-", - "T168694-", - "G168695-", - "A168696-", - "T168697-", - "T168698-", - "A168699-", - "T168700-", - "C168701-", - "T168702-", - "G168703-", - "G168704-", - "G168705-", - "T168706-", - "A168707-", - "T168708-", - "T168709-", - "A168710-", - "A168711-", - "T168712-", - "C168713-", - "A168714-", - "A168715-", - "A168716-", - "G168717-", - "T168718-", - "T168719-", - "T168720-", - "C168721-", - "A168722-", - "T168723-", - "G168724-", - "A168725-", - "A168726-", - "T168727-", - "T168731C", - "G168732A", - "A168734T", - "C168737G", - "G168741-", - "A168742-", - "A168743-", - "T168744-", - "A168748T", - "C168750G", - "G168755-", - "A168756-", - "T168757-", - "A168758-", - "G168759-", - "A168760-", - "G168761-", - "A168762-", - "A168763-", - "T168764-", - "C168765-", - "A168766-", - "T168767-", - "G168768-", - "C168769-", - "G168770-", - "T168771-", - "C168772-", - "A168773-", - "G168774-", - "A168775-", - "T168777G", - "C169569-", - "A169570-", - "T169571-", - "T169572-", - "T169573-", - "A169574-", - "A169575-", - "T169576-", - "A169577-", - "A169578-", - "G169579-", - "G169580-", - "A169581-", - "C169582-", - "A169583-", - "T169584-", - "T169585-", - "G169586-", - "G169587-", - "A169588-", - "T169589-", - "A169590-", - "T169591-", - "G169592-", - "T169593-", - "G169594-", - "G169595-", - "A169596-", - "A169597-", - "A169598-", - "A169599-", - "G169600-", - "T169601-", - "G169602-", - "A169603-", - "T169604-", - "G169605-", - "T169606-", - "A169607-", - "T169608-", - "G169609-", - "G169610-", - "A169611-", - "A169612-", - "G169613-", - "T169614-", - "T169615-", - "A169616-", - "G169617-", - "T169618-", - "A169619-", - "C169620-", - "A169621-", - "T169622-", - "T169623-", - "A169624-", - "T169625-", - "C169626-", - "A169627-", - "A169628-", - "C169629-", - "T169630-", - "T169631-", - "C169632-", - "T169633-", - "C169634-", - "C169635-", - "T169636-", - "T169637-", - "A169638-", - "T169639-", - "T169640-", - "G169641-", - "A169642-", - "T169643-", - "T169644-", - "G169645-", - "A169646-", - "A169647-", - "A169648-", - "A169649-", - "T169650-", - "G169651-", - "A169652-", - "A169653-", - "A169654-", - "A169655-", - "T169656-", - "A169657-", - "T169658-", - "A169659-", - "A169660-", - "A169661-", - "T169662-", - "A169663-", - "G169664-", - "T169665-", - "T169666-", - "T169667-", - "T169668-", - "T169669-", - "A169670-", - "T169671-", - "G169672-", - "T169673-", - "A169674-", - "T169675-", - "A169676-", - "G169677-", - "C169678-", - "G169679-", - "G169680-", - "T169681-", - "A169682-", - "T169683-", - "C169684-", - "T169685-", - "A169686-", - "C169687-", - "C169688-", - "C169689-", - "T169690-", - "A169691-", - "T169692-", - "A169693-", - "G169694-", - "T169695-", - "T169696-", - "T169697-", - "T169698-", - "A169699-", - "T169700-", - "T169701-", - "G169702-", - "C169703-", - "T169704-", - "T169705-", - "A169706-", - "C169707-", - "T169708-", - "A169709-", - "C169710-", - "T169711-", - "A169712-", - "A169713-", - "C169714-", - "A169715-", - "T169716-", - "G169717-", - "G169718-", - "A169719-", - "T169720-", - "T169721-", - "C169728-", - "A169729-", - "G169730-", - "A169731-", - "T169732-", - "A169733-", - "C169734-", - "A169735-", - "G169736-", - "A169737-", - "T169738-", - "A169739-", - "C169740-", - "A169741-", - "G169742-", - "A169743-", - "T169744-", - "A169745-", - "C169746-", - "A169747-", - "G169748-", - "A169749-", - "T169750-", - "A169751-", - "C169752-", - "A169753-", - "G169754-", - "A169755-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "T187260-", - "G187261-", - "T187262-", - "T187263-", - "T187264-", - "A187265-", - "G187266-", - "A187267-", - "A187268-", - "T187269-", - "C187270-", - "A187271-", - "T187272-", - "T187273-", - "T187274-", - "A187275-", - "T187276-", - "C187277-", - "A187278-", - "T187279-", - "A187280-", - "A187281-", - "C187282-", - "A187290-", - "A187291-", - "T187292-", - "A187293-", - "A187294-", - "A187295-", - "T187296-", - "T187297-", - "C187298-", - "A187299-", - "T187300-", - "C187301-", - "A187302-", - "A187303-", - "C187304-", - "G187305-", - "A187306-", - "A187307-", - "T187308-", - "A187309-", - "T187310-", - "C187311-", - "G187312-", - "A187313-", - "T187314-", - "A187315-", - "A187316-", - "A187317-", - "G187318-", - "A187319-", - "C187320-", - "C187321-", - "T187322-", - "C187323-", - "T187324-", - "T187325-", - "G187326-", - "T187327-", - "A187328-", - "A187329-", - "T187330-", - "T187331-", - "C187332-", - "G187333-", - "A187334-", - "G187335-", - "T187336-", - "A187337-", - "T187338-", - "A187339-", - "G187340-", - "G187341-", - "A187342-", - "A187343-", - "G187344-", - "T187345-", - "A187346-", - "G187347-", - "T187348-", - "A187349-", - "T187350-", - "T187351-", - "A187352-", - "C187353-", - "C187354-", - "A187355-", - "T187356-", - "A187357-", - "T187358-", - "C187359-", - "A187360-", - "A187361-", - "C187362-", - "T187363-", - "T187364-", - "C187365-", - "C187366-", - "G187367-", - "A187368-", - "G187369-", - "T187370-", - "T187371-", - "A187372-", - "A187373-", - "C187374-", - "A187375-", - "A187376-", - "T187377-", - "T187378-", - "A187379-", - "C187380-", - "T187381-", - "C187382-", - "T187383-", - "A187384-", - "A187385-", - "A187386-", - "A187387-", - "C187388-", - "A187389-", - "T187390-", - "G187391-", - "A187392-", - "G187393-", - "G187394-", - "A187395-", - "T187396-", - "T187397-", - "G187398-", - "T187399-", - "A187400-", - "C187401-", - "T187402-", - "C187403-", - "T187407A", - "C187408G", - "T187414-", - "G187415-", - "G187416-", - "A187417-", - "G187418-", - "A187419-", - "T187420-", - "C187421-", - "A187422-", - "C187423-", - "T187424-", - "A187425-", - "T187426-", - "T187427-", - "T187428-", - "A187429-", - "G187430-", - "T187431-", - "C187432-", - "G187433-", - "T187434-", - "T187435-", - "G187436-", - "A187437-", - "T187438-", - "A187439-", - "A187440-", - "A187441-", - "C187442-", - "T187443-", - "A187444-", - "G187445-", - "T187446-", - "A187447-", - "A187448-", - "C187449-", - "C187450-", - "T187451-", - "C187452-", - "A187453-", - "G187454-", - "G187455-", - "T187456-", - "T187457-", - "T187458-", - "C187459-", - "T187460-", - "T187461-", - "T187462-", - "A187463-", - "C187464-", - "A187465-", - "A187466-", - "A187467-", - "C187468-", - "G187469-", - "A187470-", - "T187471-", - "A187472-", - "A187473-", - "A187474-", - "G187475-", - "T187476-", - "A187477-", - "C187478-", - "A187479-", - "A187480-", - "C187481-", - "A187482-", - "T187483-", - "C187484-", - "A187485-", - "A187486-", - "G187487-", - "A187488-", - "C187489-", - "C187490-", - "T187491-", - "C187492-", - "A187493-", - "C187494-", - "A187495-", - "A187496-", - "C187497-", - "A187498-", - "C187499-", - "A187500-", - "G187501-", - "T187502-", - "G187503-", - "C187504-", - "A187505-", - "A187506-", - "G187507-", - "A187508-", - "T187509-", - "T187510-", - "A187511-", - "A187512-", - "T187513-", - "C187514-", - "A187520-", - "T187521-", - "C187522-", - "A187523-", - "A187524-", - "A187525-", - "T187526-", - "G187527-", - "T187528-", - "A187529-", - "A187530-", - "T187531-", - "T187532-", - "C187533-", - "T187534-", - "G187535-", - "G187536-", - "A187537-", - "G187538-", - "G187539-", - "A187540-", - "G187541-", - "A187542-", - "A187543-", - "T187544-", - "C187545-", - "T187546-", - "A187547-", - "G187548-", - "A187549-", - "C187550-", - "A187551-", - "A187552-", - "C187553-", - "T187554-", - "A187555-", - "A187556-", - "C187557-", - "A187558-", - "C187559-", - "C187560-", - "C187561-", - "A187562-", - "C187563-", - "G187564-", - "G187565-", - "C187566-", - "G187567-", - "A187568-", - "A187569-", - "G187570-", - "T187571-", - "A187572-", - "T187573-", - "A187574-", - "C187575-", - "T187576-", - "T187577-", - "T187578-", - "A187579-", - "T187580-", - "G187581-", - "C187582-", - "C187583-", - "T187584-", - "C187585-", - "A187586-", - "T187587-", - "T187588-", - "C187589-", - "A187590-", - "G187591-", - "A187592-", - "A187593-", - "A187594-", - "C187595-", - "G187596-", - "G187597-", - "T187598-", - "A187599-", - "A187600-", - "C187601-", - "T187602-", - "G187603-", - "T187604-", - "A187605-", - "G187606-", - "T187607-", - "A187608-", - "G187609-", - "G187610-", - "A187611-", - "G187612-", - "A187613-", - "C187614-", - "T187615-", - "G187616-", - "T187617-", - "C187618-", - "T187619-", - "C187620-", - "T187621-", - "C187622-", - "T187623-", - "A187624-", - "A187625-", - "T187626-", - "C187627-", - "T187628-", - "C187629-", - "G187630-", - "A187631-", - "T187632-", - "G187633-", - "T187634-", - "A187635-", - "T187636-", - "A187637-", - "T187638-", - "A187639-", - "T187640-", - "A187641-", - "A187642-", - "T187643-", - "A187644-", - "T187645-", - "A187646-", - "T187647-", - "A187648-", - "C187649-", - "C187650-", - "A187651-", - "A187652-", - "T187653-", - "A187654-", - "C187655-", - "G187656-", - "G187657-", - "A187658-", - "C187659-", - "G187660-", - "C187661-", - "G187662-", - "A187663-", - "T187664-", - "A187665-", - "T187666-", - "A187667-", - "T187668-", - "T187669-", - "C187670-", - "C187671-", - "G187672-", - "A187673-", - "C187674-", - "A187675-", - "T187676-", - "G187677-", - "A187678-", - "A187679-", - "T187680-", - "G187681-", - "G187682-", - "C187683-", - "G187684-", - "T187685-", - "C187686-", - "G187687-", - "C187688-", - "T187689-", - "T187690-", - "A187691-", - "T187692-", - "C187693-", - "A187694-", - "T187695-", - "A187696-", - "T187697-", - "G187698-", - "T187699-", - "T187700-", - "A187701-", - "T187702-", - "A187703-", - "T187704-", - "C187705-", - "C187706-", - "T187707-", - "A187708-", - "A187709-", - "A187710-", - "T187711-", - "G187712-", - "T187713-", - "T187714-", - "G187715-", - "A187716-", - "T187717-", - "C187718-", - "A187719-", - "T187720-", - "A187721-", - "T187722-", - "T187723-", - "C187724-", - "C187725-", - "A187726-", - "C187727-", - "A187728-", - "A187729-", - "A187730-", - "T187731-", - "G187732-", - "A187733-", - "T187734-", - "T187735-", - "G187736-", - "T187737-", - "G187738-", - "A187739-", - "A187740-", - "C187741-", - "G187742-", - "A187743-", - "G187744-", - "A187745-", - "T187746-", - "T187747-", - "A187748-", - "A187749-", - "A187750-", - "T187751-", - "C187752-", - "A187753-", - "T187754-", - "C187755-", - "T187756-", - "A187757-", - "A187758-", - "C187759-", - "A187760-", - "A187761-", - "A187762-", - "T187763-", - "A187764-", - "A187765-", - "T187766-", - "T187767-", - "A187768-", - "G187769-", - "T187770-", - "T187771-", - "T187772-", - "T187773-", - "T187774-", - "T187775-", - "A187776-", - "T187777-", - "G187778-", - "A187779-", - "C187780-", - "A187781-", - "T187782-", - "T187783-", - "A187784-", - "A187785-", - "C187786-", - "A187787-", - "T187788-", - "A187789-", - "T187790-", - "A187791-", - "A187792-", - "T187793-", - "A187794-", - "A187795-", - "A187796-", - "T187797-", - "A187798-", - "A187799-", - "A187800-", - "T187801-", - "T187802-", - "A187803-", - "A187804-", - "T187805-", - "C187806-", - "A187807-", - "T187808-", - "T187809-", - "A187810-", - "T187811-", - "T187812-", - "G187813-", - "A187814-", - "C187815-", - "T187816-", - "T187817-", - "A187818-", - "A187819-", - "C187820-", - "G187821-", - "A187822-", - "T187823-", - "G187824-", - "A187825-", - "C187826-", - "G187827-", - "A187828-", - "A187829-", - "A187830-", - "G187831-", - "T187832-", - "T187833-", - "A187834-", - "T187835-", - "C187836-", - "A187837-", - "T187838-", - "T187839-", - "A187840-", - "T187841-", - "C187842-", - "T187843-", - "T187844-", - "A187845-", - "G187846-", - "G187847-", - "A187848-", - "T187849-", - "T187850-", - "C187851-", - "T187852-", - "T187853-", - "G187854-", - "A187855-", - "T187856-", - "T187857-", - "A187858-", - "T187859-", - "T187860-", - "A187861-", - "A187862-", - "T187863-", - "A187864-", - "C187865-", - "A187866-", - "A187867-", - "A187868-", - "T187869-", - "T187870-", - "C187871-", - "G187872-", - "T187873-", - "A188115-", - "G188116-", - "T188117-", - "T188118-", - "A188119-", - "T188120-", - "C188121-", - "G188122-", - "T188123-", - "C188124-", - "T188125-", - "C188126-", - "C188127-", - "T188128-", - "T188129-", - "A188130-", - "A188131-", - "A188132-", - "G188133-", - "C188134-", - "T188135-", - "T188136-", - "C188137-", - "T188138-", - "G188139-", - "A188140-", - "T188141-", - "G188142-", - "G188143-", - "T188144-", - "A188145-", - "A188146-", - "C188147-", - "T188148-", - "G188149-", - "T188150-", - "G188151-", - "T188152-", - "T188153-", - "A188154-", - "C188155-", - "A188156-", - "T188157-", - "G188158-", - "T188159-", - "G188160-", - "C188161-", - "T188162-", - "C188163-", - "C188164-", - "T188165-", - "A188166-", - "A188167-", - "A188168-", - "A188169-", - "C188170-", - "A188171-", - "A188172-", - "A188173-", - "A188174-", - "T188175-", - "A188176-", - "T188177-", - "G188178-", - "G188179-", - "T188180-", - "C188181-", - "G188182-", - "T188183-", - "G188184-", - "T188185-", - "G188186-", - "T188187-", - "A188188-", - "C188189-", - "G188190-", - "G188191-", - "A188192-", - "A188193-", - "A188194-", - "G188195-", - "A188196-", - "A188197-", - "A188198-", - "G188199-", - "G188200-", - "A188201-", - "G188202-", - "A188203-", - "A188204-", - "A188205-", - "A188206-", - "T188207-", - "G188208-", - "A188209-", - "T188210-", - "A188211-", - "T188212-", - "G188213-", - "G188214-", - "A188215-", - "A188216-", - "T188217-", - "A188218-", - "C188219-", - "C188220-", - "A188221-", - "T188222-", - "T188223-", - "T188224-", - "G188225-", - "T188226-", - "A188227-", - "A188228-", - "G188229-", - "A188230-", - "A188231-", - "A188232-", - "T188233-", - "G188234-", - "T188235-", - "C188236-", - "G188237-", - "G188238-", - "A188239-", - "A188240-", - "G188241-", - "G188242-", - "G188243-", - "T188244-", - "A188245-", - "C188246-", - "T188247-", - "T188248-", - "A188249-", - "T188250-", - "T188251-", - "C188252-", - "A188253-", - "G188254-", - "A188255-", - "T188256-", - "A188257-", - "T188258-", - "T188259-", - "G188260-", - "T188261-", - "A188262-", - "T188263-", - "C188264-", - "T188265-", - "G188266-", - "A188267-", - "C188268-", - "T188269-", - "C188270-", - "T188271-", - "G188272-", - "A188273-", - "T188274-", - "C188275-", - "A188276-", - "A188277-", - "T188278-", - "G188279-", - "T188280-", - "A188281-", - "A188282-", - "A188283-", - "C188284-", - "C188285-", - "T188286-", - "A188287-", - "T188288-", - "G188289-", - "A188290-", - "C188291-", - "A188292-", - "A188293-", - "G188294-", - "A188295-", - "T188296-", - "A188297-", - "A188298-", - "G188299-", - "A188300-", - "C188301-", - "T188302-", - "T188303-", - "A188304-", - "C188305-", - "T188306-", - "C188307-", - "G188308-", - "C188309-", - "A188310-", - "T188311-", - "C188312-", - "T188313-", - "A188314-", - "C188315-", - "T188316-", - "G188317-", - "G188318-", - "A188319-", - "T188320-", - "A188321-", - "G188322-", - "A188323-", - "C188324-", - "A188325-", - "T188326-", - "A188327-", - "A188328-", - "A188329-", - "T188330-", - "A188331-", - "T188332-", - "C188333-", - "C188334-", - "T188335-", - "C188336-", - "C188337-", - "T188338-", - "C188339-", - "G188340-", - "T188341-", - "A188342-", - "A188343-", - "T188344-", - "A188345-", - "A188346-", - "T188347-", - "G188348-", - "A188349-", - "A188350-", - "A188351-", - "T188352-", - "A188353-", - "T188354-", - "A188355-", - "A188356-", - "T188357-", - "A188358-", - "T188359-", - "A188360-", - "C188361-", - "A188362-", - "C188363-", - "T188364-", - "A188365-", - "A188366-", - "T188367-", - "T188368-", - "A188369-", - "T188370-", - "T188371-", - "A188372-", - "A188373-", - "T188374-", - "A188375-", - "T188376-", - "C188377-", - "A188378-", - "A188379-", - "T188380-", - "C188381-", - "G188382-", - "A188383-", - "G188384-", - "T188385-", - "A188386-", - "T188387-", - "T188388-", - "A188389-", - "A188390-", - "C188391-", - "A188392-", - "T188393-", - "A188394-", - "T188395-", - "A188396-", - "A188397-", - "G188398-", - "T188399-", - "T188400-", - "A188401-", - "T188402-", - "T188403-", - "T188404-", - "T188405-", - "T188406-", - "A188407-", - "A188408-", - "A188409-", - "C188410-", - "C188411-", - "C188412-", - "C188413-", - "T188414-", - "T188415-", - "T188416-", - "T188417-", - "G188418-", - "G188419-", - "G188420-", - "T188421-", - "T188422-", - "C188423-", - "C188424-", - "G188425-", - "T188426-", - "C188427-", - "C188428-", - "T188429-", - "A188430-", - "A188431-", - "A188432-", - "C188433-", - "G188434-", - "G188435-", - "C188436-", - "G188437-", - "T188438-", - "T188439-", - "T188440-", - "C188441-", - "G188442-", - "G188443-", - "T188444-", - "C188445-", - "T188446-", - "G188447-", - "T188448-", - "G188449-", - "T188450-", - "C188451-", - "G188452-", - "C188453-", - "C188454-", - "A188455-", - "C188456-", - "C188457-", - "A188458-", - "T188459-", - "G188460-", - "G188461-", - "T188462-", - "C188463-", - "A188464-", - "C188465-", - "A188466-", - "C188467-", - "C188468-", - "G188469-", - "A188470-", - "G188471-", - "C188472-", - "C188473-", - "T188474-", - "C188475-", - "T188476-", - "G188477-", - "C188478-", - "G188479-", - "T188480-", - "G188481-", - "C188482-", - "T188483-", - "C188484-", - "C188485-", - "T188486-", - "C188487-", - "C188488-", - "A188489-", - "T188490-", - "C188491-", - "G188492-", - "A188493-", - "G188494-", - "G188495-", - "A188496-", - "C188497-", - "G188498-", - "A188499-", - "C188500-", - "T188501-", - "T188502-", - "C188503-", - "A188504-", - "A188505-", - "C188506-", - "T188507-", - "A188508-", - "T188509-", - "G188510-", - "A188511-", - "C188512-", - "A188513-", - "G188514-", - "C188515-", - "T188516-", - "C188517-", - "G188518-", - "G188519-", - "T188520-", - "G188521-", - "G188522-", - "C188523-", - "G188524-", - "T188525-", - "C188526-", - "T188527-", - "G188528-", - "C188529-", - "C188530-", - "A188531-", - "G188532-", - "C188533-", - "G188534-", - "T188535-", - "G188536-", - "T188537-", - "A188538-", - "C188539-", - "A188540-", - "T188541-", - "A188542-", - "C188543-", - "G188544-", - "A188545-", - "A188546-", - "T188547-", - "G188548-", - "G188549-", - "C188550-", - "A188551-", - "T188552-", - "T188553-", - "T188554-", - "C188555-", - "T188556-", - "A188557-", - "A188558-", - "G188559-", - "A188560-", - "A188561-", - "A188562-", - "A188563-", - "G188564-", - "T188565-", - "C188566-", - "T188567-", - "A188568-", - "C188569-", - "G188570-", - "G188571-", - "T188572-", - "A188573-", - "T188574-", - "C188575-", - "C188576-", - "T188577-", - "T188578-", - "T188579-", - "C188580-", - "T188581-", - "A188582-", - "C188583-", - "A188584-", - "A188585-", - "T188586-", - "T188587-", - "T188588-", - "C188589-", - "C188590-", - "T188591-", - "T188592-", - "T188593-", - "A188594-", - "A188595-", - "C188596-", - "A188597-", - "A188598-", - "C188599-", - "G188600-", - "G188601-", - "C188602-", - "A188603-", - "A188604-", - "C188605-", - "A188606-", - "G188607-", - "C188608-", - "T188609-", - "G188610-", - "C188611-", - "A188612-", - "G188613-", - "T188614-", - "A188615-", - "T188616-", - "T188617-", - "T188618-", - "T188619-", - "T188620-", - "A188621-", - "T188622-", - "A188623-", - "C188624-", - "T188625-", - "T188626-", - "T188627-", - "G188628-", - "A188629-", - "A188630-", - "T188631-", - "G188632-", - "C188633-", - "A188634-", - "T188635-", - "C188636-", - "G188637-", - "G188638-", - "A188639-", - "C188640-", - "A188641-", - "T188642-", - "T188643-", - "T188644-", - "A188645-", - "T188646-", - "A188647-", - "C188648-", - "A188649-", - "A188650-", - "G188651-", - "G188652-", - "G188653-", - "A188654-", - "G188655-", - "T188656-", - "C188657-", - "C188658-", - "T188659-", - "G188660-", - "T188661-", - "T188662-", - "C188663-", - "T188664-", - "A188665-", - "A188666-", - "T188667-", - "A188668-", - "T188669-", - "T188670-", - "G188671-", - "G188672-", - "C188673-", - "A188674-", - "T188675-", - "C188676-", - "A188677-", - "A188678-", - "T188679-", - "G188680-", - "T188681-", - "T188682-", - "C188683-", - "G188684-", - "G188685-", - "A188686-", - "T188687-", - "C188688-", - "T188689-", - "A188690-", - "T188691-", - "A188692-", - "G188693-", - "G188694-", - "C188695-", - "T188696-", - "T188697-", - "G188698-", - "A188699-", - "T188700-", - "T188701-", - "T188702-", - "T188703-", - "C188704-", - "G188705-", - "C188706-", - "A188707-", - "T188708-", - "T188709-", - "G188710-", - "A188711-", - "C188712-", - "T188713-", - "T188714-", - "T188715-", - "A188716-", - "C188717-", - "A188718-", - "C188719-", - "A188720-", - "G188721-", - "A188722-", - "C188723-", - "A188724-", - "T188725-", - "G188726-", - "A188727-", - "A188728-", - "C188729-", - "A188730-", - "T188731-", - "C188732-", - "C188733-", - "C188734-", - "C188735-", - "T188736-", - "G188737-", - "A188738-", - "A188739-", - "T188740-", - "C188741-", - "T188742-", - "G188743-", - "T188744-", - "A188745-", - "C188746-", - "A188747-", - "T188748-", - "A188749-", - "C188750-", - "T188751-", - "T188752-", - "T188753-", - "G188754-", - "T188755-", - "G188756-", - "G188757-", - "A188758-", - "T188759-", - "T188760-", - "T188761-", - "A188762-", - "C188763-", - "A188764-", - "C188765-", - "T188766-", - "G188767-", - "T188768-", - "T188769-", - "A188770-", - "G188771-", - "A188772-", - "A188773-", - "T188774-", - "C188775-", - "T188776-", - "C188777-", - "T188778-", - "A188779-", - "A188780-", - "C188781-", - "G188782-", - "C188783-", - "T188784-", - "G188785-", - "G188786-", - "C188787-", - "C188788-", - "T188789-", - "C188790-", - "T188791-", - "G188792-", - "T188793-", - "T188794-", - "G188795-", - "T188796-", - "T188797-", - "A188798-", - "C188799-", - "T188800-", - "T188801-", - "T188802-", - "C188803-", - "T188804-", - "A188805-", - "T188806-", - "G188807-", - "A188808-", - "T188809-", - "G188810-", - "C188811-", - "A188812-", - "C188813-", - "G188814-", - "T188815-", - "A188816-", - "T188817-", - "C188818-", - "G188819-", - "T188820-", - "T188821-", - "A188822-", - "T188823-", - "G188824-", - "C188825-", - "A188826-", - "A188827-", - "G188828-", - "C188829-", - "T188830-", - "T188831-", - "T188832-", - "C188833-", - "A188834-", - "T188835-", - "G188836-", - "T188837-", - "T188838-", - "G188839-", - "A188840-", - "C188841-", - "T188842-", - "A188843-", - "C188844-", - "T188845-", - "G188846-", - "C188847-", - "A188848-", - "G188849-", - "T188850-", - "G188851-", - "T188852-", - "T188853-", - "T188854-", - "C188855-", - "T188856-", - "T188857-", - "G188858-", - "C188859-", - "T188860-", - "C188861-", - "T188862-", - "G188863-", - "A188864-", - "C188865-", - "T188866-", - "A188867-", - "C188868-", - "A188869-", - "T188870-", - "A188871-", - "T188872-", - "A188873-", - "C188874-", - "T188875-", - "C188876-", - "T188877-", - "A188878-", - "C188879-", - "A188880-", - "A188881-", - "T188882-", - "C188883-", - "A188884-", - "A188885-", - "A188886-", - "G188887-", - "A188888-", - "A188890-", - "G188891-", - "A188892-", - "T188893-", - "T188894-", - "T188895-", - "C188896-", - "A188897-", - "G188898-", - "T188899-", - "A188900-", - "A188901-", - "A188902-", - "C188903-", - "T188904-", - "T188905-", - "G188906-", - "T188907-", - "A188908-", - "A188909-", - "C188910-", - "A188911-", - "G188912-", - "G188913-", - "A188914-", - "T188915-", - "T188916-", - "G188917-", - "T188918-", - "T188919-", - "T188920-", - "G188921-", - "C188922-", - "T188923-", - "G188924-", - "C188925-", - "T188926-", - "T188927-", - "T188928-", - "C188929-", - "T188930-", - "G188931-", - "G188932-", - "A188933-", - "T188934-", - "T188935-", - "T188936-", - "T188937-", - "A188938-", - "A188939-", - "T188940-", - "T188941-", - "T188942-", - "T188943-", - "G188944-", - "T188945-", - "C188946-", - "A188947-", - "G188948-", - "G188949-", - "A188950-", - "G188951-", - "T188952-", - "C188953-", - "T188954-", - "T188955-", - "G188956-", - "A188957-", - "G188958-", - "G188959-", - "A188960-", - "T188961-", - "A188962-", - "A188963-", - "A188964-", - "G188965-", - "T188966-", - "T188967-", - "T188968-", - "A188969-", - "A188970-", - "A188971-", - "A188972-", - "T188973-", - "A188974-", - "G188975-", - "A188976-", - "A188977-", - "T188978-", - "T188979-", - "A188980-", - "A188981-", - "T188982-", - "A188983-", - "A188984-", - "A188985-", - "G188986-", - "A188987-", - "A188988-", - "C188989-", - "A188990-", - "T188991-", - "A188992-", - "T188993-", - "A188994-", - "G188995-", - "G188996-", - "T188997-", - "C188998-", - "A188999-", - "T189000-", - "T189001-", - "T189002-", - "T189003-", - "T189004-", - "T189005-", - "A189006-", - "A189007-", - "A189008-", - "C189009-", - "A189010-", - "T189011-", - "G189012-", - "G189013-", - "A189014-", - "T189015-", - "A189016-", - "G189017-", - "A189018-", - "A189019-", - "A189020-", - "C189021-", - "C189022-", - "A189023-", - "A190128-", - "T190129-", - "A190130-", - "T190131-", - "T190132-", - "A190133-", - "T190134-", - "T190135-", - "A190136-", - "A190137-", - "T190138-", - "G190139-", - "G190140-", - "A190141-", - "T190142-", - "A190143-", - "T190144-", - "A190145-", - "T190146-", - "A190147-", - "G190148-", - "A190149-", - "T190150-", - "A190151-", - "A190152-", - "C190153-", - "G190154-", - "C190155-", - "A190156-", - "A190157-", - "T190158-", - "A190159-", - "G190160-", - "G190161-", - "G190162-", - "A190163-", - "C190164-", - "T190165-", - "A190166-", - "A190167-", - "T190168-", - "A190169-", - "G190170-", - "T190171-", - "A190172-", - "T190173-", - "T190174-", - "G190175-", - "T190176-", - "A190177-", - "A190178-", - "A190179-", - "A190180-", - "G190181-", - "G190345A" - ], - "OPG071": [ - "R246Q" - ], - "OPG192": [ - "D39X", - "N40-", - "I41-", - "E42-", - "N43-", - "S44-", - "Y45-", - "T46-", - "D47-", - "D48-", - "N49-", - "N50-", - "E51-", - "L52-", - "V53-", - "L54-", - "N55-", - "F56-", - "K57-", - "E58-", - "Y59-", - "T60-", - "I61-", - "S62-", - "I63-", - "I64-", - "T65-", - "E66-", - "S67-", - "C68-", - "D69-", - "V70-", - "G71-", - "F72-", - "D73-", - "S74-", - "I75-", - "D76-", - "I77-", - "D78-", - "V79-", - "I80-", - "N81-", - "D82-", - "Y83-", - "*183X" - ], - "OPG195": [ - "T118N", - "L119-", - "C120-", - "I121-", - "S122-", - "V123-", - "Y124-", - "C125-", - "D126-", - "Q127X", - "E128Q", - "A129-", - "G130-", - "D131-", - "I132-", - "K133-", - "F134-", - "E135-", - "E136-", - "Y137-", - "T138-", - "Q139-", - "E140-", - "S141-", - "S142-", - "D143-", - "I144-", - "S145-", - "I146-", - "K149L", - "Y150-", - "D151-", - "S152-", - "S153-", - "C154-", - "I155-", - "D156-", - "Y157-", - "L158-", - "G159-", - "I160-", - "N161-", - "Q162-", - "S163-", - "F164-", - "M165-", - "N166-", - "C168H", - "I169F", - "R170G", - "R171X", - "I172X", - "T174R", - "D176-", - "R177-", - "E178-", - "S179-", - "C180-", - "V181-", - "R182-", - "I183S", - "*222X" - ], - "OPG197": [ - "M1-", - "Y2-", - "S3-", - "G4-", - "I5-", - "Y6-", - "P7-", - "I8-", - "V9-", - "L10-", - "L11-", - "L12-", - "T13-", - "T14-", - "N15-", - "M16-", - "D17-", - "X18-", - "X20-", - "D21-", - "T22-", - "D23-", - "T24-", - "D25-", - "T26-", - "D27-", - "T28-", - "D29X" - ] - }, - "labels": { - "aa": "OPG071: R246Q; OPG192: D39X, N40-, I41-, E42-, N43-, S44-, Y45-, T46-, D47-, D48-, N49-, N50-, E51-, L52-, V53-, L54-, N55-, F56-, K57-, E58-, Y59-, T60-, I61-, S62-, I63-, I64-, T65-, E66-, S67-, C68-, D69-, V70-, G71-, F72-, D73-, S74-, I75-, D76-, I77-, D78-, V79-, I80-, N81-, D82-, Y83-, *183X; OPG195: T118N, L119-, C120-, I121-, S122-, V123-, Y124-, C125-, D126-, Q127X, E128Q, A129-, G130-, D131-, I132-, K133-, F134-, E135-, E136-, Y137-, T138-, Q139-, E140-, S141-, S142-, D143-, I144-, S145-, I146-, K149L, Y150-, D151-, S152-, S153-, C154-, I155-, D156-, Y157-, L158-, G159-, I160-, N161-, Q162-, S163-, F164-, M165-, N166-, C168H, I169F, R170G, R171X, I172X, T174R, D176-, R177-, E178-, S179-, C180-, V181-, R182-, I183S, *222X; OPG197: M1-, Y2-, S3-, G4-, I5-, Y6-, P7-, I8-, V9-, L10-, L11-, L12-, T13-, T14-, N15-, M16-, D17-, X18-, X20-, D21-, T22-, D23-, T24-, D25-, T26-, D27-, T28-, D29X" - } - } - }, - { - "name": "NODE_0000010", - "node_attrs": { - "div": 19, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C23353T", - "C51809T", - "G69678A", - "C125492T", - "C128174T", - "-188889A" - ], - "OPG039": [ - "D256N" - ], - "OPG071": [ - "R877Q" - ], - "OPG146": [ - "D50N" - ] - }, - "labels": { - "aa": "OPG039: D256N; OPG071: R877Q; OPG146: D50N" - } - }, - "children": [ - { - "name": "NODE_0000011", - "node_attrs": { - "div": 20, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T27971C", - "T146862-", - "A146863-", - "T146864-", - "T146865-", - "T146866-", - "T146867-", - "A146868-", - "T146869-", - "A146870-", - "T146871-", - "T146872-", - "T146873-", - "T146874-", - "A146875-", - "T146876-", - "A146877-", - "T146878-", - "T146879-", - "T146880-", - "-173274A", - "-173275T", - "-173276A", - "-173277T" - ] - } - }, - "children": [ - { - "name": "MK783033", - "node_attrs": { - "div": 30, - "author": { - "author": "Yinka-Ogunleye,A., Aruna,O., Dalhat,M., Ogoina,D., McCollum,A., Disu,Y., Mamadu,I., Akinpelu,A., Ahmad,A., Burga,J., Ndoreraho,A., Nkunzimana,E., Manneh,L., Mohammed,A., Adeoye,O., Tom-Aba,D., Silenou,B., Ipadeola,O., Saleh,M., Adeyemo,A., Nwadiutor,I., Aworabhi,N., Uke,P., John,D., Wakama,P., Reynolds,M., Mauldin,M., Doty,J., Wilkins,K., Musa,J., Khalakdina,A., Adedeji,A., Mba,N., Ojo,O., Krause,G., Ihekweazu,C., Mauldin,M.R., Li,Y., Gao,J.", - "value": "Yinka-Ogunleye,A., Aruna,O., Dalhat,M., Ogoina,D., McCollum,A., Disu,Y., Mamadu,I., Akinpelu,A., Ahmad,A., Burga,J., Ndoreraho,A., Nkunzimana,E., Manneh,L., Mohammed,A., Adeoye,O., Tom-Aba,D., Silenou,B., Ipadeola,O., Saleh,M., Adeyemo,A., Nwadiutor,I., Aworabhi,N., Uke,P., John,D., Wakama,P., Reynolds,M., Mauldin,M., Doty,J., Wilkins,K., Musa,J., Khalakdina,A., Adedeji,A., Mba,N., Ojo,O., Krause,G., Ihekweazu,C., Mauldin,M.R., Li,Y., Gao,J." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2017-10-09" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "CDC, NCEZID/DHCPP/PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MK783033" - }, - "strain": { - "value": "MK783033" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "C25731T", - "C25768T", - "C26020T", - "A56968G", - "G102267T", - "C117099T", - "G129583A", - "C155707T", - "G161701A", - "-169722C", - "-169723A", - "-169724G", - "-169725A", - "-169726T", - "-169727A", - "T187428C", - "-196602A" - ], - "OPG042": [ - "D360N" - ], - "OPG074": [ - "L53S" - ], - "OPG121": [ - "G160C" - ], - "OPG136": [ - "R830Q" - ], - "OPG188": [ - "V36I" - ], - "OPG197": [ - "X18S", - "-19D", - "X20T", - "X101*" - ] - }, - "labels": { - "aa": "OPG042: D360N; OPG074: L53S; OPG121: G160C; OPG136: R830Q; OPG188: V36I; OPG197: X18S, -19D, X20T, X101*" - } - } - }, - { - "name": "MPXV_Nigeria_2017_2948", - "node_attrs": { - "div": 20, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2017-10-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_Nigeria_2017_2948" - }, - "strain": { - "value": "OP535323" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.3" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV_Nigeria_2017_2947", - "node_attrs": { - "div": 20, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2017-10-XX" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_Nigeria_2017_2947" - }, - "strain": { - "value": "OP535335" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.3" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000012", - "node_attrs": { - "div": 24, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T595-", - "C92053T", - "C123000T", - "C146052T", - "C150831T", - "C151305T", - "-169722C", - "-169723A", - "-169724G", - "-169725A", - "-169726T", - "-169727A" - ], - "OPG113": [ - "S108L" - ], - "OPG143": [ - "E106K" - ], - "OPG197": [ - "X18S", - "-19D", - "X20T", - "X101*" - ] - }, - "labels": { - "aa": "OPG113: S108L; OPG143: E106K; OPG197: X18S, -19D, X20T, X101*" - } - }, - "children": [ - { - "name": "MPXV/015/19", - "node_attrs": { - "div": 27, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2019-03-14" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/015/19" - }, - "strain": { - "value": "OP612677" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C56351T", - "G74032A", - "T76079-", - "A89100-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "A173300-", - "T173301-", - "G190782A" - ], - "NBT03_gp174": [ - "E125K" - ], - "OPG074": [ - "E259K" - ], - "OPG094": [ - "A85T" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG109": [ - "F116X", - "*796X" - ] - }, - "labels": { - "aa": "NBT03_gp174: E125K; OPG074: E259K; OPG094: A85T; OPG097: K266X, *345X; OPG109: F116X, *796X" - } - } - }, - { - "name": "NODE_0000013", - "node_attrs": { - "div": 53, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C2930T", - "C18493T", - "C18908T", - "G21898A", - "G23626A", - "C25254T", - "C29199T", - "G36901A", - "G44085A", - "G63034A", - "G75099A", - "G75144A", - "G76509A", - "C87659T", - "G115332A", - "C115572T", - "G122627A", - "C128771T", - "C140739T", - "A149394-", - "G151519T", - "G151875A", - "C160008T", - "C160312T", - "G165130A", - "G168862A", - "-173274A", - "-173275T", - "-173276A", - "-173277T", - "G174491A", - "G176289A", - "G176366A", - "C177703T", - "G194280A", - "A196603-", - "A196604-" - ], - "OPG003": [ - "E560K" - ], - "OPG037": [ - "S179L" - ], - "OPG039": [ - "H165Y" - ], - "OPG045": [ - "E22K" - ], - "OPG064": [ - "S605L" - ], - "OPG082": [ - "S140L" - ], - "OPG097": [ - "H123Y" - ], - "OPG109": [ - "E597K" - ], - "OPG133": [ - "R42Q", - "S122F" - ], - "OPG143": [ - "T230M" - ], - "OPG174": [ - "M1X", - "*347X" - ], - "OPG178": [ - "G4V", - "D123N" - ], - "OPG205": [ - "A212T", - "M237I", - "S683L" - ] - }, - "labels": { - "aa": "OPG003: E560K; OPG037: S179L; OPG039: H165Y; OPG045: E22K; OPG064: S605L; OPG082: S140L; OPG097: H123Y; OPG109: E597K; OPG133: R42Q, S122F; OPG143: T230M; OPG174: M1X, *347X; OPG178: G4V, D123N; OPG205: A212T, M237I, S683L" - } - }, - "children": [ - { - "name": "9000360", - "node_attrs": { - "div": 53, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000360" - }, - "strain": { - "value": "OP413718" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133169-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-" - ] - } - } - }, - { - "name": "9000450", - "node_attrs": { - "div": 53, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000450" - }, - "strain": { - "value": "OP536812" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.3" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000029", - "node_attrs": { - "div": 18, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C23564T", - "C72362T", - "C83326T", - "G87230A", - "G87297A", - "G91728A", - "C119296T", - "C121320T", - "G125249A", - "G148412A", - "C164832T", - "C168120T" - ], - "OPG092": [ - "D196N" - ], - "OPG105": [ - "S734L" - ], - "OPG109": [ - "H740Y" - ], - "OPG136": [ - "D98N" - ], - "OPG139": [ - "A17T" - ], - "OPG145": [ - "E435K" - ], - "OPG193": [ - "L263F" - ] - }, - "labels": { - "aa": "OPG092: D196N; OPG105: S734L; OPG109: H740Y; OPG136: D98N; OPG139: A17T; OPG145: E435K; OPG193: L263F", - "clade": "A.1" - } - }, - "children": [ - { - "name": "MN648051", - "node_attrs": { - "div": 22, - "author": { - "author": "Cohen Gihon,I., Israeli,O., Shifman,O., Erez,N., Melamed,S., Paran,N., Beth-Din,A., Zvi,A.", - "value": "Cohen Gihon,I., Israeli,O., Shifman,O., Erez,N., Melamed,S., Paran,N., Beth-Din,A., Zvi,A." - }, - "country": { - "value": "Israel" - }, - "date": { - "value": "2018-10-04" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MN648051" - }, - "strain": { - "value": "MN648051" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T595-", - "C8772T", - "C91363T", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "A147593T", - "G150568A", - "G177273A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A196603-" - ], - "OPG172": [ - "E56V" - ], - "OPG205": [ - "D540N" - ] - }, - "labels": { - "aa": "OPG172: E56V; OPG205: D540N" - } - } - }, - { - "name": "MPXV-UK_P1", - "node_attrs": { - "div": 21, - "author": { - "author": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y.", - "value": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2018-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV-UK_P1" - }, - "strain": { - "value": "MT903343" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "G28838A", - "G92349A", - "-173274A", - "-173275T", - "-173276A", - "-173277T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "G188494A", - "-196602A" - ], - "OPG045": [ - "A142V" - ], - "OPG113": [ - "E207K" - ] - }, - "labels": { - "aa": "OPG045: A142V; OPG113: E207K" - } - } - }, - { - "name": "MPXV-M5320_M15_Bayelsa", - "node_attrs": { - "div": 20, - "author": { - "author": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y.", - "value": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2018-08-14" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV-M5320_M15_Bayelsa" - }, - "strain": { - "value": "MT903341" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "A3152-", - "G3153-", - "A3154-", - "T3155-", - "T3156-", - "C3157-", - "G3158-", - "A3159-", - "A3160-", - "T3161-", - "C3162-", - "T3163-", - "C3164-", - "T3165-", - "T3166-", - "T3167-", - "G3168-", - "A3169-", - "G3170-", - "G3171-", - "A3172-", - "G3173-", - "A3174-", - "C3175-", - "T3176-", - "T3177-", - "A3178-", - "T3179-", - "G3180-", - "T3181-", - "C3182-", - "A3183-", - "C3184-", - "G3185-", - "A3186-", - "C3187-", - "T3188-", - "A3189-", - "C3190-", - "A3191-", - "T3192-", - "T3193-", - "T3194-", - "T3195-", - "T3196-", - "C3197-", - "G3198-", - "A3199-", - "T3200-", - "G3201-", - "A3202-", - "T3203-", - "G3204-", - "G3205-", - "A3206-", - "A3207-", - "T3208-", - "C3209-", - "T3210-", - "A3211-", - "T3212-", - "C3213-", - "T3214-", - "T3215-", - "A3216-", - "T3217-", - "C3218-", - "G3219-", - "A3220-", - "A3221-", - "T3222-", - "G3223-", - "A3224-", - "T3225-", - "A3226-", - "T3227-", - "A3228-", - "T3229-", - "T3230-", - "T3231-", - "T3232-", - "T3233-", - "C3234-", - "A3235-", - "T3236-", - "A3237-", - "A3238-", - "A3239-", - "T3240-", - "A3241-", - "C3242-", - "A3243-", - "C3244-", - "T3245-", - "T3246-", - "T3247-", - "T3248-", - "A3249-", - "T3250-", - "A3251-", - "G3252-", - "T3253-", - "C3254-", - "C3255-", - "T3256-", - "C3257-", - "G3258-", - "T3259-", - "T3260-", - "T3261-", - "A3262-", - "A3263-", - "A3264-", - "C3265-", - "A3266-", - "G3267-", - "A3268-", - "A3269-", - "T3270-", - "T3271-", - "T3272-", - "A3273-", - "G3274-", - "T3275-", - "A3276-", - "T3277-", - "G3278-", - "T3279-", - "A3280-", - "G3281-", - "T3282-", - "T3283-", - "C3284-", - "C3285-", - "G3286-", - "C3287-", - "A3288-", - "A3289-", - "A3290-", - "T3291-", - "G3292-", - "A3293-", - "C3294-", - "T3295-", - "C3296-", - "G3297-", - "T3298-", - "C3299-", - "C3300-", - "C3301-", - "T3302-", - "T3303-", - "A3304-", - "A3305-", - "T3306-", - "A3307-", - "G3308-", - "G3309-", - "C3310-", - "A3311-", - "G3312-", - "T3313-", - "A3314-", - "G3315-", - "G3316-", - "C3317-", - "T3318-", - "A3319-", - "T3320-", - "T3321-", - "A3322-", - "T3323-", - "C3324-", - "T3325-", - "T3326-", - "C3327-", - "T3328-", - "T3329-", - "T3330-", - "A3331-", - "C3332-", - "G3333-", - "T3334-", - "A3335-", - "G3336-", - "T3337-", - "G3338-", - "A3339-", - "T3340-", - "C3341-", - "G3342-", - "T3343-", - "C3344-", - "G3345-", - "T3346-", - "A3347-", - "G3348-", - "G3349-", - "G3350-", - "A3351-", - "G3352-", - "A3353-", - "G3354-", - "A3355-", - "A3356-", - "C3357-", - "T3358-", - "C3359-", - "C3360-", - "G3361-", - "A3362-", - "C3363-", - "A3364-", - "T3365-", - "C3366-", - "T3367-", - "T3368-", - "G3369-", - "T3370-", - "A3371-", - "G3372-", - "A3373-", - "A3374-", - "C3375-", - "A3376-", - "A3377-", - "C3378-", - "G3379-", - "A3380-", - "T3381-", - "T3382-", - "T3383-", - "A3384-", - "A3385-", - "T3386-", - "C3387-", - "A3388-", - "T3389-", - "A3390-", - "G3391-", - "G3392-", - "T3393-", - "A3394-", - "G3395-", - "A3396-", - "G3397-", - "A3398-", - "T3399-", - "A3400-", - "C3401-", - "T3402-", - "T3403-", - "T3404-", - "C3405-", - "A3406-", - "G3407-", - "T3408-", - "C3409-", - "T3410-", - "G3411-", - "T3412-", - "G3413-", - "G3414-", - "T3415-", - "G3416-", - "G3417-", - "A3418-", - "T3419-", - "A3420-", - "A3421-", - "T3422-", - "G3423-", - "T3424-", - "C3425-", - "A3426-", - "T3427-", - "T3428-", - "A3429-", - "A3430-", - "C3431-", - "G3432-", - "A3433-", - "C3434-", - "A3435-", - "T3436-", - "C3437-", - "C3438-", - "G3439-", - "C3440-", - "C3441-", - "T3442-", - "T3443-", - "G3444-", - "T3445-", - "A3446-", - "T3447-", - "A3448-", - "T3449-", - "A3450-", - "A3451-", - "T3452-", - "G3453-", - "T3454-", - "T3455-", - "T3456-", - "C3457-", - "T3458-", - "G3459-", - "T3460-", - "T3461-", - "T3462-", - "T3463-", - "C3464-", - "A3465-", - "A3466-", - "A3467-", - "C3468-", - "A3469-", - "C3470-", - "C3471-", - "A3472-", - "A3473-", - "G3474-", - "T3475-", - "C3476-", - "G3477-", - "A3478-", - "A3479-", - "T3480-", - "A3481-", - "C3482-", - "T3483-", - "G3484-", - "T3485-", - "C3486-", - "T3487-", - "T3488-", - "A3489-", - "T3490-", - "C3491-", - "G3492-", - "T3493-", - "C3494-", - "T3495-", - "T3496-", - "T3497-", - "A3498-", - "G3499-", - "T3500-", - "C3501-", - "G3502-", - "G3503-", - "A3504-", - "A3505-", - "G3506-", - "G3507-", - "T3508-", - "T3509-", - "G3510-", - "A3511-", - "T3512-", - "G3513-", - "T3514-", - "C3515-", - "G3516-", - "T3517-", - "A3518-", - "T3519-", - "C3520-", - "C3521-", - "G3522-", - "A3523-", - "T3524-", - "G3525-", - "T3526-", - "A3527-", - "T3528-", - "A3529-", - "C3530-", - "G3531-", - "A3532-", - "G3533-", - "G3534-", - "T3535-", - "A3536-", - "T3537-", - "G3538-", - "A3539-", - "G3540-", - "G3541-", - "C3542-", - "A3543-", - "A3544-", - "C3545-", - "A3546-", - "T3547-", - "T3548-", - "G3549-", - "T3550-", - "T3551-", - "A3552-", - "T3553-", - "T3554-", - "G3555-", - "C3556-", - "A3557-", - "A3558-", - "T3559-", - "T3560-", - "C3561-", - "T3562-", - "G3563-", - "G3564-", - "A3565-", - "A3566-", - "G3567-", - "G3568-", - "C3569-", - "G3570-", - "G3571-", - "T3572-", - "A3573-", - "T3574-", - "G3575-", - "A3576-", - "A3577-", - "G3578-", - "A3579-", - "G3580-", - "G3581-", - "A3582-", - "G3583-", - "T3584-", - "C3585-", - "A3586-", - "T3587-", - "T3588-", - "G3589-", - "T3590-", - "A3591-", - "T3592-", - "T3593-", - "A3594-", - "T3595-", - "A3596-", - "G3597-", - "T3598-", - "A3599-", - "T3600-", - "T3601-", - "C3602-", - "G3603-", - "T3604-", - "C3605-", - "T3606-", - "T3607-", - "T3608-", - "C3609-", - "T3610-", - "G3611-", - "A3612-", - "A3613-", - "T3614-", - "G3615-", - "T3616-", - "C3617-", - "G3618-", - "A3619-", - "A3620-", - "T3621-", - "C3622-", - "T3623-", - "A3624-", - "T3625-", - "C3626-", - "T3627-", - "A3628-", - "G3629-", - "T3630-", - "A3631-", - "G3632-", - "A3633-", - "T3634-", - "A3635-", - "C3636-", - "C3637-", - "G3638-", - "T3639-", - "A3640-", - "G3641-", - "T3642-", - "A3643-", - "T3644-", - "A3645-", - "T3646-", - "T3647-", - "G3648-", - "A3649-", - "G3650-", - "A3651-", - "G3652-", - "A3653-", - "G3654-", - "C3655-", - "G3656-", - "A3657-", - "C3658-", - "T3659-", - "T3660-", - "C3661-", - "C3662-", - "A3663-", - "T3664-", - "A3665-", - "T3666-", - "C3667-", - "C3668-", - "T3669-", - "T3670-", - "G3671-", - "A3672-", - "T3673-", - "T3674-", - "A3675-", - "T3676-", - "G3677-", - "T3678-", - "T3679-", - "T3680-", - "T3681-", - "A3682-", - "T3683-", - "G3684-", - "A3685-", - "A3686-", - "T3687-", - "A3688-", - "G3689-", - "A3690-", - "T3691-", - "A3692-", - "A3693-", - "A3694-", - "G3695-", - "T3696-", - "A3697-", - "G3698-", - "A3699-", - "T3700-", - "G3701-", - "T3702-", - "T3703-", - "G3704-", - "T3705-", - "C3706-", - "C3707-", - "T3708-", - "T3709-", - "C3710-", - "T3711-", - "T3712-", - "C3713-", - "C3714-", - "T3715-", - "T3716-", - "T3717-", - "T3718-", - "G3719-", - "T3720-", - "A3721-", - "A3722-", - "T3723-", - "T3724-", - "T3725-", - "C3726-", - "C3727-", - "C3728-", - "G3729-", - "T3730-", - "A3731-", - "T3732-", - "T3733-", - "T3734-", - "T3735-", - "T3736-", - "G3737-", - "T3738-", - "T3739-", - "C3740-", - "G3741-", - "T3742-", - "G3743-", - "C3744-", - "C3745-", - "A3746-", - "A3747-", - "T3748-", - "T3749-", - "G3750-", - "A3751-", - "G3752-", - "T3753-", - "A3754-", - "A3755-", - "C3756-", - "A3757-", - "T3758-", - "T3759-", - "A3760-", - "T3761-", - "G3762-", - "A3763-", - "G3764-", - "A3765-", - "A3766-", - "T3767-", - "A3768-", - "T3769-", - "G3770-", - "A3771-", - "C3772-", - "C3773-", - "T3774-", - "G3775-", - "T3776-", - "T3777-", - "G3778-", - "C3779-", - "A3780-", - "C3781-", - "A3782-", - "A3783-", - "T3784-", - "C3785-", - "G3786-", - "T3787-", - "T3788-", - "C3789-", - "T3790-", - "T3791-", - "T3792-", - "A3793-", - "T3794-", - "G3795-", - "T3796-", - "A3797-", - "T3798-", - "T3799-", - "C3800-", - "C3801-", - "A3802-", - "T3803-", - "G3804-", - "A3805-", - "T3806-", - "G3807-", - "G3808-", - "G3809-", - "T3810-", - "G3811-", - "T3812-", - "A3813-", - "C3814-", - "A3815-", - "A3816-", - "T3817-", - "C3818-", - "A3819-", - "A3820-", - "G3821-", - "A3822-", - "T3823-", - "T3824-", - "A3825-", - "T3826-", - "T3827-", - "A3828-", - "C3829-", - "G3830-", - "T3831-", - "A3832-", - "T3833-", - "C3834-", - "C3835-", - "T3836-", - "C3837-", - "G3838-", - "T3839-", - "A3840-", - "T3841-", - "C3842-", - "G3843-", - "G3844-", - "C3845-", - "T3846-", - "C3847-", - "C3848-", - "T3849-", - "C3850-", - "G3851-", - "A3852-", - "G3853-", - "A3854-", - "T3855-", - "A3856-", - "A3857-", - "A3858-", - "A3859-", - "G3860-", - "A3861-", - "G3862-", - "C3863-", - "A3864-", - "T3865-", - "A3866-", - "C3867-", - "A3868-", - "C3869-", - "C3870-", - "A3871-", - "C3872-", - "A3873-", - "C3874-", - "G3875-", - "A3876-", - "G3877-", - "G3878-", - "A3879-", - "C3880-", - "T3881-", - "A3882-", - "T3883-", - "G3884-", - "T3885-", - "T3886-", - "T3887-", - "G3888-", - "G3889-", - "T3890-", - "A3891-", - "T3892-", - "A3893-", - "C3894-", - "T3895-", - "G3896-", - "T3897-", - "T3898-", - "G3899-", - "A3900-", - "A3901-", - "G3902-", - "G3903-", - "T3904-", - "A3905-", - "A3906-", - "G3907-", - "T3908-", - "G3909-", - "T3910-", - "G3911-", - "T3912-", - "A3913-", - "A3914-", - "C3915-", - "G3916-", - "G3917-", - "C3918-", - "G3919-", - "T3920-", - "A3921-", - "T3922-", - "T3923-", - "T3924-", - "C3925-", - "C3926-", - "G3927-", - "A3928-", - "T3929-", - "T3930-", - "T3931-", - "T3932-", - "C3933-", - "G3934-", - "T3935-", - "A3936-", - "A3937-", - "C3938-", - "C3939-", - "G3940-", - "C3941-", - "G3942-", - "T3943-", - "T3944-", - "A3945-", - "A3946-", - "T3947-", - "G3948-", - "T3949-", - "T3950-", - "T3951-", - "G3952-", - "C3953-", - "T3954-", - "C3955-", - "C3956-", - "A3957-", - "T3958-", - "G3959-", - "A3960-", - "T3961-", - "C3962-", - "T3963-", - "A3964-", - "T3965-", - "T3966-", - "A3967-", - "T3968-", - "C3969-", - "G3970-", - "C3971-", - "G3972-", - "T3973-", - "A3974-", - "G3975-", - "A3976-", - "T3977-", - "G3978-", - "A3979-", - "A3980-", - "T3981-", - "C3982-", - "G3983-", - "C3984-", - "T3985-", - "T3986-", - "C3987-", - "T3988-", - "C3989-", - "A3990-", - "G3991-", - "C3992-", - "T3993-", - "C3994-", - "G3995-", - "C3996-", - "A3997-", - "T3998-", - "C3999-", - "T4000-", - "T4001-", - "A4002-", - "G4003-", - "T4004-", - "G4005-", - "T4006-", - "G4007-", - "A4008-", - "C4009-", - "T4010-", - "C4011-", - "T4012-", - "T4013-", - "T4014-", - "G4015-", - "A4016-", - "C4017-", - "T4018-", - "T4019-", - "G4020-", - "T4021-", - "A4022-", - "A4023-", - "T4024-", - "A4025-", - "A4026-", - "T4027-", - "T4028-", - "G4029-", - "C4030-", - "T4031-", - "T4032-", - "T4033-", - "C4034-", - "G4035-", - "T4036-", - "G4037-", - "G4038-", - "A4039-", - "A4040-", - "C4041-", - "G4042-", - "C4043-", - "G4044-", - "G4045-", - "A4046-", - "T4047-", - "A4048-", - "T4049-", - "G4050-", - "T4051-", - "G4052-", - "T4053-", - "T4054-", - "T4055-", - "A4056-", - "C4057-", - "A4058-", - "G4059-", - "T4060-", - "A4061-", - "G4062-", - "T4063-", - "A4064-", - "A4065-", - "T4066-", - "G4067-", - "A4068-", - "A4069-", - "G4070-", - "A4071-", - "G4072-", - "A4073-", - "A4074-", - "G4075-", - "T4076-", - "G4077-", - "A4078-", - "G4079-", - "T4080-", - "C4081-", - "C4082-", - "A4083-", - "T4084-", - "C4085-", - "C4086-", - "T4087-", - "C4088-", - "A4089-", - "T4090-", - "C4091-", - "G4092-", - "A4093-", - "C4094-", - "G4095-", - "C4096-", - "A4097-", - "A4098-", - "T4099-", - "T4100-", - "A4101-", - "G4102-", - "G4103-", - "G4104-", - "T4105-", - "C4106-", - "A4107-", - "G4108-", - "A4109-", - "T4110-", - "C4111-", - "C4112-", - "T4113-", - "T4114-", - "T4115-", - "A4116-", - "G4117-", - "T4118-", - "C4119-", - "A4120-", - "A4121-", - "T4122-", - "A4123-", - "A4124-", - "T4125-", - "T4126-", - "T4127-", - "G4128-", - "T4129-", - "A4130-", - "C4131-", - "A4132-", - "G4133-", - "A4134-", - "A4135-", - "C4136-", - "G4137-", - "T4138-", - "A4139-", - "A4140-", - "T4141-", - "A4142-", - "G4143-", - "T4144-", - "T4145-", - "T4146-", - "A4147-", - "A4148-", - "G4149-", - "C4150-", - "T4151-", - "C4152-", - "C4153-", - "C4154-", - "A4155-", - "T4156-", - "T4157-", - "G4158-", - "A4159-", - "A4160-", - "T4161-", - "T4162-", - "T4163-", - "A4164-", - "T4165-", - "A4166-", - "T4167-", - "C4168-", - "T4169-", - "A4170-", - "A4171-", - "G4172-", - "A4173-", - "T4174-", - "A4175-", - "A4176-", - "C4177-", - "A4178-", - "C4179-", - "A4180-", - "G4181-", - "C4182-", - "A4183-", - "A4184-", - "T4185-", - "A4186-", - "G4187-", - "A4188-", - "T4189-", - "C4190-", - "G4191-", - "G4192-", - "A4193-", - "T4194-", - "G4195-", - "A4196-", - "T4197-", - "T4198-", - "T4199-", - "A4200-", - "C4201-", - "T4202-", - "A4203-", - "A4204-", - "A4205-", - "G4206-", - "T4207-", - "C4208-", - "A4209-", - "T4210-", - "C4211-", - "A4212-", - "A4213-", - "T4214-", - "G4215-", - "G4216-", - "G4217-", - "G4218-", - "T4219-", - "C4220-", - "C4221-", - "G4222-", - "T4223-", - "T4224-", - "A4225-", - "G4226-", - "T4227-", - "A4228-", - "T4229-", - "A4230-", - "T4231-", - "C4232-", - "A4233-", - "A4234-", - "A4235-", - "G4236-", - "A4237-", - "T4238-", - "C4239-", - "T4240-", - "T4241-", - "G4242-", - "T4243-", - "T4244-", - "A4245-", - "T4246-", - "C4247-", - "G4248-", - "A4249-", - "T4250-", - "T4251-", - "G4252-", - "A4253-", - "T4254-", - "A4255-", - "G4256-", - "T4257-", - "G4258-", - "A4259-", - "A4260-", - "T4261-", - "G4262-", - "A4263-", - "A4264-", - "T4265-", - "C4266-", - "A4267-", - "G4268-", - "A4269-", - "T4270-", - "A4271-", - "G4272-", - "T4273-", - "G4274-", - "G4275-", - "T4276-", - "G4277-", - "T4278-", - "A4279-", - "G4280-", - "A4281-", - "G4282-", - "G4283-", - "A4284-", - "A4285-", - "T4286-", - "A4287-", - "T4288-", - "G4289-", - "T4290-", - "C4291-", - "C4292-", - "T4293-", - "T4294-", - "T4295-", - "T4296-", - "T4297-", - "T4298-", - "A4299-", - "T4300-", - "C4301-", - "C4302-", - "T4303-", - "T4304-", - "G4305-", - "C4306-", - "T4307-", - "A4308-", - "T4309-", - "C4310-", - "A4311-", - "A4312-", - "A4313-", - "G4314-", - "T4315-", - "T4316-", - "A4317-", - "C4318-", - "G4319-", - "C4320-", - "A4321-", - "T4322-", - "G4323-", - "C4324-", - "C4325-", - "G4326-", - "T4327-", - "G4328-", - "G4329-", - "C4330-", - "G4331-", - "T4332-", - "A4333-", - "A4334-", - "C4335-", - "A4336-", - "A4337-", - "T4338-", - "A4339-", - "T4340-", - "C4341-", - "T4342-", - "T4343-", - "T4344-", - "A4345-", - "A4346-", - "T4347-", - "A4348-", - "C4349-", - "A4350-", - "G4351-", - "A4352-", - "T4353-", - "G4354-", - "G4355-", - "A4356-", - "T4357-", - "T4358-", - "A4359-", - "A4360-", - "A4361-", - "T4362-", - "C4363-", - "G4364-", - "T4365-", - "G4366-", - "T4367-", - "A4368-", - "T4369-", - "T4370-", - "C4371-", - "A4372-", - "T4373-", - "C4374-", - "G4375-", - "T4376-", - "A4377-", - "T4378-", - "A4379-", - "G4380-", - "C4381-", - "A4382-", - "A4383-", - "T4384-", - "G4385-", - "T4386-", - "A4387-", - "A4388-", - "T4389-", - "G4390-", - "G4391-", - "A4392-", - "G4393-", - "A4394-", - "G4395-", - "T4396-", - "T4397-", - "A4398-", - "C4399-", - "C4400-", - "A4401-", - "C4402-", - "A4403-", - "T4404-", - "T4405-", - "T4406-", - "T4407-", - "A4408-", - "G4409-", - "T4410-", - "C4411-", - "G4412-", - "T4413-", - "T4414-", - "T4415-", - "A4416-", - "T4417-", - "T4418-", - "C4419-", - "A4420-", - "G4421-", - "A4422-", - "T4423-", - "C4424-", - "G4425-", - "C4426-", - "A4427-", - "G4428-", - "T4429-", - "G4430-", - "T4431-", - "T4432-", - "T4433-", - "A4434-", - "A4435-", - "T4436-", - "A4437-", - "A4438-", - "C4439-", - "T4440-", - "A4441-", - "A4442-", - "T4443-", - "T4444-", - "T4445-", - "A4446-", - "A4447-", - "A4448-", - "C4449-", - "A4450-", - "G4451-", - "A4452-", - "T4453-", - "G4454-", - "A4455-", - "G4456-", - "A4457-", - "T4458-", - "G4459-", - "A4460-", - "T4461-", - "A4462-", - "T4463-", - "A4464-", - "T4465-", - "C4466-", - "C4467-", - "A4468-", - "C4469-", - "A4470-", - "T4471-", - "C4472-", - "A4473-", - "A4474-", - "A4475-", - "G4476-", - "A4477-", - "A4478-", - "T4479-", - "G4480-", - "C4481-", - "G4482-", - "A4483-", - "G4484-", - "A4485-", - "T4486-", - "A4487-", - "C4488-", - "A4489-", - "T4490-", - "A4491-", - "T4492-", - "G4493-", - "A4494-", - "C4495-", - "A4496-", - "G4497-", - "A4498-", - "C4499-", - "A4500-", - "T4501-", - "T4502-", - "A4503-", - "T4504-", - "T4505-", - "G4506-", - "A4507-", - "C4508-", - "A4509-", - "G4510-", - "A4511-", - "A4512-", - "A4513-", - "T4514-", - "G4515-", - "T4516-", - "G4517-", - "A4518-", - "C4519-", - "C4520-", - "T4521-", - "T4522-", - "C4523-", - "A4524-", - "T4525-", - "T4526-", - "A4527-", - "T4528-", - "C4529-", - "A4530-", - "C4531-", - "C4532-", - "G4533-", - "T4534-", - "C4535-", - "G4536-", - "T4537-", - "C4538-", - "C4539-", - "A4540-", - "T4541-", - "A4542-", - "A4543-", - "A4544-", - "T4545-", - "G4546-", - "C4547-", - "G4548-", - "T4549-", - "T4550-", - "A4551-", - "G4552-", - "G4553-", - "T4554-", - "A4555-", - "C4556-", - "G4557-", - "T4558-", - "A4559-", - "C4560-", - "C4561-", - "A4562-", - "C4563-", - "A4564-", - "T4565-", - "A4566-", - "C4567-", - "T4568-", - "A4569-", - "T4570-", - "C4571-", - "G4572-", - "T4573-", - "T4574-", - "A4575-", - "A4576-", - "C4577-", - "G4578-", - "A4579-", - "T4580-", - "G4581-", - "C4582-", - "G4583-", - "C4584-", - "A4585-", - "C4586-", - "A4587-", - "A4588-", - "T4589-", - "C4590-", - "T4591-", - "C4592-", - "G4593-", - "T4594-", - "C4595-", - "C4596-", - "A4597-", - "T4598-", - "T4599-", - "T4600-", - "C4601-", - "A4602-", - "T4603-", - "C4604-", - "C4605-", - "A4606-", - "T4607-", - "C4608-", - "T4609-", - "T4610-", - "C4611-", - "A4612-", - "T4613-", - "A4614-", - "A4615-", - "T4616-", - "G4617-", - "A4618-", - "T4619-", - "T4620-", - "T4621-", - "A4622-", - "C4623-", - "T4624-", - "T4625-", - "T4626-", - "T4627-", - "T4628-", - "C4629-", - "A4630-", - "T4631-", - "A4632-", - "A4633-", - "T4634-", - "T4635-", - "A4636-", - "G4637-", - "A4638-", - "G4639-", - "A4640-", - "A4641-", - "A4642-", - "A4643-", - "A4644-", - "G4645-", - "A4646-", - "T4647-", - "C4648-", - "A4649-", - "A4650-", - "G4651-", - "G4652-", - "T4653-", - "A4654-", - "T4655-", - "A4656-", - "A4657-", - "A4658-", - "A4659-", - "A4660-", - "T4661-", - "T4662-", - "A4663-", - "G4664-", - "A4665-", - "A4666-", - "G4667-", - "T4668-", - "G4669-", - "T4670-", - "T4671-", - "A4672-", - "G4673-", - "A4674-", - "C4675-", - "T4676-", - "A4677-", - "T4678-", - "A4679-", - "A4680-", - "A4681-", - "C4682-", - "T4683-", - "A4684-", - "A4685-", - "C4686-", - "T4687-", - "T4688-", - "A4689-", - "T4690-", - "G4691-", - "A4692-", - "C4693-", - "T4694-", - "T4695-", - "A4696-", - "A4697-", - "C4698-", - "T4699-", - "A4700-", - "A4701-", - "C4702-", - "T4703-", - "T4704-", - "A4705-", - "T4706-", - "G4707-", - "A4708-", - "C4709-", - "T4710-", - "T4711-", - "A4712-", - "A4713-", - "C4714-", - "T4715-", - "A4716-", - "A4717-", - "C4718-", - "T4719-", - "T4720-", - "A4721-", - "T4722-", - "G4723-", - "A4724-", - "C4725-", - "T4726-", - "T4727-", - "A4728-", - "A4729-", - "C4730-", - "T4731-", - "A4732-", - "A4733-", - "C4734-", - "T4735-", - "T4736-", - "A4737-", - "T4738-", - "G4739-", - "A4740-", - "C4741-", - "T4742-", - "T4743-", - "A4744-", - "A4745-", - "C4746-", - "T4747-", - "A4748-", - "A4749-", - "C4750-", - "T4751-", - "T4752-", - "A4753-", - "T4754-", - "G4755-", - "A4756-", - "C4757-", - "T4758-", - "T4759-", - "A4760-", - "A4761-", - "C4762-", - "T4763-", - "A4764-", - "A4765-", - "C4766-", - "T4767-", - "T4768-", - "A4769-", - "T4770-", - "G4771-", - "A4772-", - "C4773-", - "T4774-", - "T4775-", - "A4776-", - "A4777-", - "C4778-", - "T4779-", - "A4780-", - "A4781-", - "C4782-", - "T4783-", - "T4784-", - "A4785-", - "T4786-", - "G4787-", - "A4788-", - "C4789-", - "T4790-", - "T4791-", - "A4792-", - "A4793-", - "C4794-", - "T4795-", - "A4796-", - "A4797-", - "C4798-", - "T4799-", - "T4800-", - "A4801-", - "T4802-", - "G4803-", - "A4804-", - "C4805-", - "T4806-", - "A4807-", - "T4808-", - "T4809-", - "A4810-", - "A4811-", - "C4812-", - "T4813-", - "C4814-", - "A4815-", - "T4816-", - "T4817-", - "T4818-", - "C4819-", - "A4820-", - "A4821-", - "G4822-", - "A4823-", - "A4824-", - "A4825-", - "G4826-", - "G4827-", - "T4828-", - "G4829-", - "G4830-", - "G4831-", - "T4832-", - "G4833-", - "G4834-", - "A4835-", - "T4836-", - "A4837-", - "G4838-", - "A4839-", - "A4840-", - "C4841-", - "T4842-", - "C4843-", - "T4844-", - "A4845-", - "T4846-", - "A4847-", - "T4848-", - "G4849-", - "A4850-", - "C4851-", - "A4852-", - "G4853-", - "C4854-", - "T4855-", - "T4856-", - "G4857-", - "T4858-", - "G4859-", - "A4860-", - "A4861-", - "A4862-", - "C4863-", - "A4864-", - "A4865-", - "T4866-", - "T4867-", - "A4868-", - "G4869-", - "A4870-", - "T4871-", - "C4872-", - "C4873-", - "C4874-", - "T4875-", - "A4876-", - "A4877-", - "T4878-", - "T4879-", - "T4880-", - "C4881-", - "T4882-", - "A4883-", - "A4884-", - "T4885-", - "G4886-", - "G4887-", - "A4888-", - "A4889-", - "G4890-", - "T4891-", - "T4892-", - "T4893-", - "T4894-", - "G4895-", - "A4896-", - "T4897-", - "A4898-", - "G4899-", - "G4900-", - "A4901-", - "G4902-", - "A4903-", - "T4904-", - "T4905-", - "G4906-", - "T4907-", - "C4908-", - "A4909-", - "T4910-", - "C4911-", - "A4912-", - "G4913-", - "T4914-", - "T4915-", - "G4916-", - "A4917-", - "T4918-", - "A4919-", - "C4920-", - "A4921-", - "T4922-", - "T4923-", - "G4924-", - "T4925-", - "T4926-", - "T4927-", - "A4928-", - "T4929-", - "T4930-", - "A4931-", - "T4932-", - "C4933-", - "T4934-", - "C4935-", - "A4936-", - "T4937-", - "C4938-", - "T4939-", - "A4940-", - "T4941-", - "T4942-", - "A4943-", - "G4944-", - "A4945-", - "G4946-", - "C4947-", - "A4948-", - "C4949-", - "G4950-", - "T4951-", - "C4952-", - "T4953-", - "G4954-", - "T4955-", - "T4956-", - "T4957-", - "A4958-", - "G4959-", - "A4960-", - "G4961-", - "C4962-", - "T4963-", - "T4964-", - "T4965-", - "A4966-", - "G4967-", - "T4968-", - "G4969-", - "A4970-", - "C4971-", - "C4972-", - "T4973-", - "G4974-", - "C4975-", - "T4976-", - "C4977-", - "G4978-", - "G4979-", - "T4980-", - "T4981-", - "A4982-", - "C4983-", - "T4984-", - "T4985-", - "C4986-", - "T4987-", - "G4988-", - "T4989-", - "G4990-", - "T4991-", - "A4992-", - "A4993-", - "A4994-", - "T4995-", - "C4996-", - "T4997-", - "T4998-", - "G4999-", - "A5000-", - "A5001-", - "T5002-", - "C5003-", - "C5004-", - "T5005-", - "T5006-", - "T5007-", - "A5008-", - "G5009-", - "T5010-", - "G5011-", - "A5012-", - "T5013-", - "A5014-", - "C5015-", - "A5016-", - "C5017-", - "T5018-", - "G5019-", - "T5020-", - "G5021-", - "T5022-", - "C5023-", - "A5024-", - "A5025-", - "A5026-", - "A5027-", - "C5028-", - "T5029-", - "G5030-", - "G5031-", - "A5032-", - "T5033-", - "G5034-", - "T5035-", - "T5036-", - "T5037-", - "A5038-", - "G5039-", - "A5040-", - "A5041-", - "T5042-", - "A5043-", - "C5044-", - "C5045-", - "T5046-", - "A5047-", - "T5048-", - "G5049-", - "T5050-", - "A5051-", - "G5052-", - "A5053-", - "A5054-", - "T5055-", - "A5056-", - "T5057-", - "G5058-", - "G5059-", - "G5060-", - "A5061-", - "A5062-", - "G5063-", - "C5064-", - "A5065-", - "T5066-", - "G5067-", - "C5068-", - "T5069-", - "T5070-", - "G5071-", - "T5072-", - "T5073-", - "T5074-", - "T5075-", - "T5076-", - "G5077-", - "T5078-", - "C5079-", - "T5080-", - "C5081-", - "T5082-", - "A5083-", - "T5084-", - "T5085-", - "A5086-", - "T5087-", - "A5088-", - "G5089-", - "A5090-", - "T5091-", - "T5092-", - "A5093-", - "A5094-", - "C5095-", - "T5096-", - "C5097-", - "A5098-", - "T5099-", - "A5100-", - "C5101-", - "A5102-", - "T5103-", - "G5104-", - "G5105-", - "T5106-", - "T5107-", - "G5108-", - "T5109-", - "A5110-", - "T5111-", - "T5112-", - "A5113-", - "T5114-", - "G5115-", - "A5116-", - "A5117-", - "T5118-", - "T5119-", - "T5120-", - "T5121-", - "C5122-", - "A5123-", - "T5124-", - "C5125-", - "T5126-", - "G5127-", - "C5128-", - "C5129-", - "T5130-", - "A5131-", - "A5132-", - "T5133-", - "G5134-", - "T5135-", - "A5136-", - "C5137-", - "T5138-", - "C5139-", - "C5140-", - "A5141-", - "A5142-", - "T5143-", - "T5144-", - "C5145-", - "T5146-", - "T5147-", - "G5148-", - "T5149-", - "T5150-", - "T5151-", - "A5152-", - "C5153-", - "A5154-", - "A5155-", - "T5156-", - "C5157-", - "A5158-", - "A5159-", - "T5160-", - "T5161-", - "A5162-", - "T5163-", - "A5164-", - "T5165-", - "A5166-", - "A5167-", - "T5168-", - "C5169-", - "A5170-", - "A5171-", - "A5172-", - "G5173-", - "A5174-", - "G5175-", - "T5176-", - "G5177-", - "A5178-", - "T5179-", - "G5180-", - "A5181-", - "T5182-", - "G5183-", - "C5184-", - "A5185-", - "T5186-", - "A5187-", - "C5188-", - "A5189-", - "C5190-", - "A5191-", - "T5192-", - "T5193-", - "A5194-", - "C5195-", - "A5196-", - "A5197-", - "A5198-", - "G5199-", - "T5200-", - "G5201-", - "A5202-", - "A5203-", - "T5204-", - "A5205-", - "A5206-", - "T5207-", - "C5208-", - "T5209-", - "A5210-", - "C5211-", - "C5212-", - "A5213-", - "T5214-", - "C5215-", - "A5216-", - "T5217-", - "A5218-", - "A5219-", - "A5220-", - "A5221-", - "T5222-", - "A5223-", - "C5224-", - "T5225-", - "T5226-", - "G5227-", - "A5228-", - "T5229-", - "A5230-", - "C5231-", - "A5232-", - "G5233-", - "A5234-", - "G5235-", - "C5236-", - "T5237-", - "T5238-", - "T5239-", - "A5240-", - "T5241-", - "C5242-", - "A5243-", - "C5244-", - "A5245-", - "T5246-", - "C5247-", - "A5248-", - "T5249-", - "G5250-", - "G5251-", - "T5252-", - "T5253-", - "T5254-", - "T5255-", - "C5256-", - "A5257-", - "A5258-", - "T5259-", - "T5260-", - "G5261-", - "T5262-", - "A5263-", - "T5264-", - "T5265-", - "A5266-", - "T5267-", - "T5268-", - "A5269-", - "A5270-", - "G5271-", - "T5272-", - "A5273-", - "T5274-", - "A5275-", - "G5276-", - "C5277-", - "T5278-", - "A5279-", - "A5280-", - "T5281-", - "T5282-", - "T5283-", - "T5284-", - "A5285-", - "T5286-", - "A5287-", - "C5288-", - "A5289-", - "G5290-", - "T5291-", - "C5292-", - "A5293-", - "A5294-", - "T5295-", - "A5296-", - "G5297-", - "A5298-", - "C5299-", - "A5300-", - "A5301-", - "T5302-", - "G5303-", - "G5304-", - "T5305-", - "T5306-", - "C5307-", - "T5308-", - "C5309-", - "T5310-", - "A5311-", - "A5312-", - "G5313-", - "C5314-", - "A5315-", - "A5316-", - "T5317-", - "A5318-", - "T5319-", - "T5320-", - "T5321-", - "C5322-", - "T5323-", - "A5324-", - "A5325-", - "T5326-", - "A5327-", - "T5328-", - "T5329-", - "T5330-", - "T5331-", - "A5332-", - "A5333-", - "G5334-", - "A5335-", - "T5336-", - "G5337-", - "T5338-", - "G5339-", - "C5340-", - "T5341-", - "T5342-", - "C5343-", - "C5344-", - "C5345-", - "T5346-", - "A5347-", - "C5348-", - "G5349-", - "G5350-", - "G5351-", - "C5352-", - "G5353-", - "A5354-", - "T5355-", - "G5356-", - "A5357-", - "C5358-", - "A5359-", - "G5360-", - "A5361-", - "T5362-", - "C5363-", - "C5364-", - "C5365-", - "C5366-", - "T5367-", - "A5368-", - "T5369-", - "C5370-", - "C5371-", - "A5372-", - "C5373-", - "G5374-", - "G5375-", - "C5376-", - "C5377-", - "A5378-", - "C5379-", - "G5380-", - "T5381-", - "C5382-", - "A5383-", - "A5384-", - "G5385-", - "A5386-", - "C5387-", - "A5388-", - "T5389-", - "G5390-", - "T5391-", - "A5392-", - "T5393-", - "A5394-", - "T5395-", - "C5396-", - "C5397-", - "A5398-", - "T5399-", - "T5400-", - "A5401-", - "C5402-", - "T5403-", - "C5404-", - "A5405-", - "T5406-", - "T5407-", - "A5408-", - "C5409-", - "T5410-", - "G5411-", - "C5412-", - "G5413-", - "T5414-", - "T5415-", - "G5416-", - "A5417-", - "C5418-", - "A5419-", - "T5420-", - "T5421-", - "T5422-", - "G5423-", - "C5424-", - "T5425-", - "C5426-", - "C5427-", - "A5428-", - "T5429-", - "T5430-", - "T5431-", - "T5432-", - "C5433-", - "T5434-", - "A5435-", - "A5436-", - "T5437-", - "A5438-", - "G5439-", - "C5440-", - "C5441-", - "A5442-", - "T5443-", - "G5444-", - "A5445-", - "T5446-", - "A5447-", - "C5448-", - "T5449-", - "A5450-", - "A5451-", - "A5452-", - "T5453-", - "C5454-", - "T5455-", - "A5456-", - "T5457-", - "A5458-", - "T5459-", - "A5460-", - "A5461-", - "C5462-", - "C5463-", - "T5464-", - "G5465-", - "C5466-", - "A5467-", - "T5468-", - "A5469-", - "G5470-", - "A5471-", - "T5472-", - "A5473-", - "G5474-", - "C5475-", - "G5476-", - "C5477-", - "G5478-", - "A5479-", - "T5480-", - "A5481-", - "A5482-", - "A5483-", - "G5484-", - "C5485-", - "A5486-", - "A5487-", - "G5488-", - "G5489-", - "T5490-", - "C5491-", - "C5492-", - "T5493-", - "T5494-", - "C5495-", - "C5496-", - "A5497-", - "C5498-", - "C5499-", - "A5500-", - "G5501-", - "C5502-", - "A5503-", - "T5504-", - "C5505-", - "T5506-", - "A5507-", - "G5508-", - "T5509-", - "T5510-", - "G5511-", - "A5512-", - "T5513-", - "T5514-", - "G5515-", - "A5516-", - "T5517-", - "A5518-", - "T5519-", - "C5520-", - "T5521-", - "T5522-", - "C5523-", - "A5524-", - "A5525-", - "T5526-", - "A5527-", - "T5528-", - "A5529-", - "T5530-", - "G5531-", - "G5532-", - "G5533-", - "A5534-", - "T5535-", - "A5536-", - "C5537-", - "A5538-", - "A5539-", - "A5540-", - "G5541-", - "C5542-", - "T5543-", - "T5544-", - "A5545-", - "T5546-", - "A5547-", - "A5548-", - "A5549-", - "T5550-", - "T5551-", - "T5552-", - "C5553-", - "T5554-", - "A5555-", - "A5556-", - "T5557-", - "A5558-", - "C5559-", - "T5560-", - "G5561-", - "T5562-", - "G5563-", - "G5564-", - "G5565-", - "T5566-", - "T5567-", - "C5568-", - "A5569-", - "T5570-", - "C5571-", - "T5572-", - "A5573-", - "C5574-", - "A5575-", - "A5576-", - "G5577-", - "G5578-", - "A5579-", - "A5580-", - "T5581-", - "C5582-", - "C5583-", - "C5584-", - "C5585-", - "T5586-", - "A5587-", - "G5588-", - "T5589-", - "A5590-", - "T5591-", - "A5592-", - "C5593-", - "T5594-", - "G5595-", - "A5596-", - "A5597-", - "T5598-", - "T5599-", - "A5600-", - "T5601-", - "T5602-", - "T5603-", - "T5604-", - "A5605-", - "T5606-", - "A5607-", - "T5608-", - "A5609-", - "G5610-", - "A5611-", - "T5612-", - "C5613-", - "T5614-", - "A5615-", - "A5616-", - "T5617-", - "T5618-", - "T5619-", - "A5620-", - "A5621-", - "C5622-", - "A5623-", - "T5624-", - "C5625-", - "A5626-", - "T5627-", - "T5628-", - "T5629-", - "T5630-", - "C5631-", - "A5632-", - "T5633-", - "C5634-", - "T5635-", - "G5636-", - "G5637-", - "G5638-", - "A5639-", - "T5640-", - "A5641-", - "C5642-", - "C5643-", - "A5644-", - "C5645-", - "A5646-", - "A5647-", - "T5648-", - "T5649-", - "C5650-", - "A5651-", - "A5652-", - "A5653-", - "A5654-", - "T5655-", - "A5656-", - "A5657-", - "A5658-", - "C5659-", - "T5660-", - "C5661-", - "A5662-", - "A5663-", - "C5664-", - "A5665-", - "A5666-", - "C5667-", - "A5668-", - "C5669-", - "T5670-", - "A5671-", - "C5672-", - "T5673-", - "T5674-", - "T5675-", - "C5676-", - "C5677-", - "T5678-", - "T5679-", - "T5680-", - "T5681-", - "T5682-", - "A5683-", - "C5684-", - "A5685-", - "T5686-", - "A5687-", - "T5688-", - "T5689-", - "C5690-", - "C5691-", - "C5692-", - "C5693-", - "T5694-", - "A5695-", - "A5696-", - "A5697-", - "A5698-", - "T5699-", - "A5700-", - "G5701-", - "G5702-", - "C5703-", - "A5704-", - "T5705-", - "T5706-", - "C5707-", - "A5708-", - "A5709-", - "G5710-", - "C5711-", - "A5712-", - "T5713-", - "T5714-", - "C5715-", - "T5716-", - "A5717-", - "T5718-", - "T5719-", - "T5720-", - "T5721-", - "A5722-", - "T5723-", - "A5724-", - "T5725-", - "A5726-", - "T5727-", - "T5728-", - "A5729-", - "C5730-", - "A5731-", - "G5732-", - "C5733-", - "C5734-", - "C5735-", - "C5736-", - "A5737-", - "T5738-", - "G5739-", - "A5740-", - "T5741-", - "C5742-", - "T5743-", - "A5744-", - "C5745-", - "C5746-", - "A5747-", - "T5748-", - "A5749-", - "A5750-", - "G5751-", - "A5752-", - "T5753-", - "C5754-", - "A5755-", - "A5756-", - "C5757-", - "A5758-", - "A5759-", - "T5760-", - "G5761-", - "T5762-", - "C5763-", - "T5764-", - "A5765-", - "T5766-", - "T5767-", - "T5768-", - "C5769-", - "T5770-", - "A5771-", - "C5772-", - "A5773-", - "T5774-", - "A5775-", - "T5776-", - "G5777-", - "C5778-", - "A5779-", - "T5780-", - "T5781-", - "A5782-", - "G5783-", - "A5784-", - "T5785-", - "A5786-", - "G5787-", - "A5788-", - "T5789-", - "A5790-", - "G5791-", - "T5792-", - "A5793-", - "A5794-", - "A5795-", - "G5796-", - "T5797-", - "A5798-", - "A5799-", - "G5800-", - "A5801-", - "G5802-", - "A5803-", - "T5804-", - "C5805-", - "T5806-", - "T5807-", - "G5808-", - "C5809-", - "A5810-", - "C5811-", - "A5812-", - "G5813-", - "A5814-", - "A5815-", - "T5816-", - "T5817-", - "A5818-", - "C5819-", - "A5820-", - "A5821-", - "T5822-", - "T5823-", - "C5824-", - "T5825-", - "T5826-", - "A5827-", - "A5828-", - "T5829-", - "A5830-", - "A5831-", - "T5832-", - "T5833-", - "A5834-", - "T5835-", - "A5836-", - "G5837-", - "A5838-", - "G5839-", - "A5840-", - "A5841-", - "A5842-", - "A5843-", - "T5844-", - "A5845-", - "T5846-", - "C5847-", - "T5848-", - "T5849-", - "C5850-", - "C5851-", - "A5852-", - "T5853-", - "A5854-", - "T5855-", - "A5856-", - "A5857-", - "T5858-", - "T5859-", - "C5860-", - "T5861-", - "T5862-", - "T5863-", - "G5864-", - "A5865-", - "C5866-", - "A5867-", - "C5868-", - "T5869-", - "A5870-", - "A5871-", - "T5872-", - "G5873-", - "C5874-", - "A5875-", - "G5876-", - "A5877-", - "T5878-", - "A5879-", - "T5880-", - "A5881-", - "A5882-", - "T5883-", - "A5884-", - "T5885-", - "C5886-", - "T5887-", - "T5888-", - "T5889-", - "A5890-", - "T5891-", - "A5892-", - "T5893-", - "G5894-", - "T5895-", - "A5896-", - "A5897-", - "T5898-", - "A5899-", - "T5900-", - "A5901-", - "T5902-", - "G5903-", - "C5904-", - "A5905-", - "A5906-", - "A5907-", - "C5908-", - "A5909-", - "G5910-", - "T5911-", - "C5912-", - "T5913-", - "A5914-", - "T5915-", - "C5916-", - "T5917-", - "A5918-", - "C5919-", - "T5920-", - "A5921-", - "T5922-", - "A5923-", - "T5924-", - "A5925-", - "C5926-", - "T5927-", - "G5928-", - "A5929-", - "T5930-", - "C5931-", - "A5932-", - "A5933-", - "T5934-", - "A5935-", - "T5936-", - "T5937-", - "A5938-", - "T5939-", - "C5940-", - "T5941-", - "C5942-", - "T5943-", - "A5944-", - "T5945-", - "G5946-", - "A5947-", - "A5948-", - "T5949-", - "C5950-", - "C5951-", - "T5952-", - "A5953-", - "A5954-", - "A5955-", - "A5956-", - "T5957-", - "A5958-", - "A5959-", - "T5960-", - "C5961-", - "A5962-", - "T5963-", - "A5964-", - "C5965-", - "A5966-", - "G5967-", - "A5968-", - "A5969-", - "C5970-", - "A5971-", - "T5972-", - "C5973-", - "T5974-", - "A5975-", - "C5976-", - "A5977-", - "G5978-", - "G5979-", - "A5980-", - "T5981-", - "C5982-", - "A5983-", - "C5984-", - "A5985-", - "A5986-", - "A5987-", - "T5988-", - "T5989-", - "G5990-", - "G5991-", - "T5992-", - "T5993-", - "C5994-", - "A5995-", - "A5996-", - "G5997-", - "G5998-", - "A5999-", - "G6000-", - "A6001-", - "A6002-", - "A6003-", - "T6004-", - "C6005-", - "T6006-", - "A6007-", - "T6008-", - "C6009-", - "A6010-", - "A6011-", - "A6012-", - "T6013-", - "A6014-", - "T6015-", - "T6016-", - "T6017-", - "T6018-", - "C6019-", - "C6020-", - "T6021-", - "G6022-", - "T6023-", - "C6024-", - "A6025-", - "A6026-", - "C6027-", - "A6028-", - "A6029-", - "C6030-", - "T6031-", - "G6032-", - "G6033-", - "T6034-", - "T6035-", - "C6036-", - "T6037-", - "A6038-", - "G6039-", - "A6040-", - "A6041-", - "C6042-", - "A6043-", - "T6044-", - "A6045-", - "A6046-", - "C6047-", - "A6048-", - "G6049-", - "T6050-", - "C6051-", - "A6052-", - "A6053-", - "C6054-", - "A6055-", - "C6056-", - "C6057-", - "T6058-", - "A6059-", - "A6060-", - "T6061-", - "C6062-", - "C6063-", - "A6064-", - "T6065-", - "G6066-", - "T6067-", - "T6068-", - "T6069-", - "T6070-", - "T6071-", - "T6072-", - "A6073-", - "T6074-", - "A6075-", - "A6076-", - "T6077-", - "C6078-", - "A6079-", - "T6080-", - "C6081-", - "T6082-", - "A6083-", - "C6084-", - "C6085-", - "A6086-", - "A6087-", - "A6088-", - "G6089-", - "A6090-", - "T6091-", - "A6092-", - "A6093-", - "T6094-", - "G6095-", - "A6096-", - "C6097-", - "C6098-", - "A6099-", - "A6100-", - "A6101-", - "G6102-", - "A6103-", - "T6104-", - "C6105-", - "G6106-", - "A6107-", - "G6108-", - "G6109-", - "T6110-", - "C6111-", - "G6112-", - "T6113-", - "C6114-", - "G6115-", - "T6116-", - "G6117-", - "A6118-", - "A6119-", - "A6120-", - "C6121-", - "T6122-", - "G6123-", - "C6124-", - "T6125-", - "C6126-", - "A6127-", - "T6128-", - "C6129-", - "G6130-", - "A6131-", - "C6132-", - "A6133-", - "G6134-", - "C6135-", - "C6136-", - "A6137-", - "T6138-", - "G6139-", - "A6140-", - "A6141-", - "A6142-", - "T6143-", - "C6144-", - "T6145-", - "A6146-", - "C6147-", - "C6148-", - "G6149-", - "A6150-", - "C6151-", - "T6152-", - "C6153-", - "C6154-", - "A6155-", - "T6156-", - "G6157-", - "G6158-", - "T6159-", - "G6160-", - "C6161-", - "G6162-", - "A6163-", - "A6164-", - "T6165-", - "C6166-", - "G6167-", - "C6168-", - "A6169-", - "C6170-", - "T6171-", - "G6172-", - "T6173-", - "C6174-", - "T6175-", - "T6176-", - "A6177-", - "T6178-", - "T6179-", - "C6180-", - "G6181-", - "C6182-", - "C6183-", - "A6184-", - "T6185-", - "T6186-", - "G6187-", - "A6188-", - "T6189-", - "T6190-", - "T6191-", - "T6192-", - "C6193-", - "A6194-", - "T6195-", - "T6196-", - "T6197-", - "T6198-", - "T6199-", - "T6200-", - "A6201-", - "T6202-", - "A6203-", - "A6204-", - "T6205-", - "T6206-", - "A6207-", - "T6208-", - "G6209-", - "T6210-", - "A6211-", - "C6212-", - "A6213-", - "T6214-", - "G6215-", - "T6216-", - "T6217-", - "T6218-", - "T6219-", - "C6220-", - "C6221-", - "T6222-", - "T6223-", - "C6224-", - "T6225-", - "A6226-", - "T6227-", - "T6228-", - "C6229-", - "T6230-", - "C6231-", - "A6232-", - "A6233-", - "G6234-", - "A6235-", - "G6236-", - "T6237-", - "C6238-", - "T6239-", - "A6240-", - "C6241-", - "A6242-", - "A6243-", - "A6244-", - "A6245-", - "A6246-", - "T6247-", - "A6248-", - "T6249-", - "A6250-", - "T6251-", - "T6252-", - "T6253-", - "T6254-", - "T6255-", - "T6256-", - "C6257-", - "G6258-", - "A6259-", - "T6260-", - "A6261-", - "T6262-", - "C6263-", - "T6264-", - "A6265-", - "A6266-", - "G6267-", - "T6268-", - "A6269-", - "C6270-", - "T6271-", - "A6272-", - "A6273-", - "G6274-", - "T6275-", - "T6276-", - "T6277-", - "T6278-", - "T6279-", - "T6280-", - "T6281-", - "A6282-", - "C6283-", - "T6284-", - "G6285-", - "T6286-", - "T6287-", - "T6288-", - "T6289-", - "T6290-", - "G6291-", - "T6292-", - "T6293-", - "A6294-", - "C6295-", - "T6296-", - "G6297-", - "T6298-", - "C6299-", - "T6300-", - "T6301-", - "C6302-", - "C6303-", - "A6304-", - "T6305-", - "T6306-", - "C6307-", - "T6308-", - "T6309-", - "C6310-", - "T6311-", - "A6312-", - "A6313-", - "C6314-", - "T6315-", - "A6316-", - "A6317-", - "A6318-", - "G6319-", - "A6320-", - "T6321-", - "C6322-", - "T6323-", - "G6324-", - "A6325-", - "G6326-", - "A6327-", - "T6328-", - "A6329-", - "A6330-", - "A6331-", - "T6332-", - "T6333-", - "A6334-", - "T6335-", - "A6336-", - "C6337-", - "A6338-", - "A6339-", - "T6340-", - "C6341-", - "T6342-", - "T6343-", - "C6344-", - "G6345-", - "C6346-", - "T6347-", - "A6348-", - "T6349-", - "C6350-", - "G6351-", - "A6352-", - "A6353-", - "C6354-", - "C6355-", - "A6356-", - "T6357-", - "T6358-", - "T6359-", - "T6360-", - "T6361-", - "G6362-", - "T6363-", - "A6364-", - "G6365-", - "T6366-", - "C6367-", - "T6368-", - "A6369-", - "A6370-", - "A6371-", - "G6372-", - "C6373-", - "C6374-", - "T6375-", - "G6376-", - "A6377-", - "A6378-", - "G6379-", - "T6380-", - "A6381-", - "A6382-", - "T6383-", - "T6384-", - "A6385-", - "A6386-", - "C6387-", - "C6388-", - "A6389-", - "A6390-", - "C6391-", - "T6392-", - "G6393-", - "T6394-", - "T6395-", - "T6396-", - "T6397-", - "T6398-", - "A6399-", - "T6400-", - "T6401-", - "A6402-", - "G6403-", - "T6404-", - "G6405-", - "G6406-", - "C6407-", - "T6408-", - "T6409-", - "T6410-", - "T6411-", - "T6412-", - "T6413-", - "C6414-", - "G6415-", - "A6416-", - "T6417-", - "C6418-", - "T6419-", - "A6420-", - "T6421-", - "C6422-", - "C6423-", - "T6424-", - "C6425-", - "G6426-", - "T6427-", - "C6428-", - "C6429-", - "T6430-", - "C6431-", - "T6432-", - "C6433-", - "A6434-", - "T6435-", - "C6436-", - "A6437-", - "T6438-", - "C6439-", - "C6440-", - "T6441-", - "T6442-", - "A6443-", - "T6444-", - "A6445-", - "T6446-", - "T6447-", - "A6448-", - "T6449-", - "T6450-", - "A6451-", - "T6452-", - "C6453-", - "A6454-", - "T6455-", - "T6456-", - "A6457-", - "T6458-", - "T6459-", - "A6460-", - "T6461-", - "C6462-", - "A6463-", - "T6464-", - "A6465-", - "G6466-", - "T6467-", - "C6468-", - "T6469-", - "A6470-", - "T6471-", - "T6472-", - "A6473-", - "A6474-", - "A6475-", - "C6476-", - "A6477-", - "C6478-", - "A6479-", - "A6480-", - "A6481-", - "T6482-", - "C6483-", - "A6484-", - "T6485-", - "C6486-", - "T6487-", - "A6488-", - "C6489-", - "G6490-", - "T6491-", - "T6492-", - "T6493-", - "A6494-", - "T6495-", - "A6496-", - "A6497-", - "C6498-", - "A6499-", - "A6500-", - "C6501-", - "A6502-", - "T6503-", - "T6504-", - "C6505-", - "T6506-", - "C6507-", - "A6508-", - "T6509-", - "T6510-", - "A6511-", - "T6512-", - "T6513-", - "A6514-", - "A6515-", - "T6516-", - "T6517-", - "A6518-", - "G6519-", - "T6520-", - "T6521-", - "C6522-", - "T6523-", - "G6524-", - "T6525-", - "A6526-", - "G6527-", - "A6528-", - "A6529-", - "T6530-", - "A6531-", - "T6532-", - "C6533-", - "T6534-", - "T6535-", - "T6536-", - "A6537-", - "A6538-", - "T6539-", - "A6540-", - "A6541-", - "T6542-", - "T6543-", - "T6544-", - "G6545-", - "G6546-", - "C6547-", - "T6548-", - "A6549-", - "T6550-", - "A6551-", - "C6552-", - "A6553-", - "T6554-", - "C6555-", - "T6556-", - "G6557-", - "T6558-", - "T6559-", - "C6560-", - "A6561-", - "A6562-", - "T6563-", - "A6564-", - "C6565-", - "T6566-", - "A6567-", - "T6568-", - "C6569-", - "T6570-", - "A6571-", - "T6572-", - "T6573-", - "G6574-", - "A6575-", - "T6576-", - "G6577-", - "A6578-", - "T6579-", - "T6580-", - "T6581-", - "C6582-", - "T6583-", - "T6584-", - "T6585-", - "T6586-", - "T6587-", - "T6588-", - "A6589-", - "A6590-", - "G6591-", - "A6592-", - "C6593-", - "T6594-", - "T6595-", - "A6596-", - "A6597-", - "A6598-", - "C6599-", - "T6600-", - "A6601-", - "G6602-", - "T6603-", - "T6604-", - "A6605-", - "T6606-", - "G6607-", - "G6608-", - "T6609-", - "A6610-", - "A6611-", - "T6612-", - "G6613-", - "A6614-", - "C6615-", - "G6616-", - "A6617-", - "T6618-", - "G6619-", - "A6620-", - "A6621-", - "A6622-", - "T6623-", - "C6624-", - "G6625-", - "A6626-", - "G6627-", - "T6628-", - "A6629-", - "G6630-", - "T6631-", - "A6632-", - "A6633-", - "C6634-", - "T6635-", - "T6636-", - "C6637-", - "T6638-", - "A6639-", - "A6640-", - "T6641-", - "A6642-", - "A6643-", - "A6644-", - "G6645-", - "A6646-", - "C6647-", - "T6648-", - "T6649-", - "G6650-", - "A6651-", - "T6652-", - "A6653-", - "T6654-", - "C6655-", - "A6656-", - "T6657-", - "T6658-", - "A6659-", - "T6660-", - "C6661-", - "A6662-", - "T6663-", - "A6664-", - "T6665-", - "G6666-", - "T6667-", - "T6668-", - "T6669-", - "G6670-", - "A6671-", - "T6672-", - "C6673-", - "G6674-", - "T6675-", - "C6676-", - "A6677-", - "T6678-", - "A6679-", - "G6680-", - "T6681-", - "T6682-", - "A6683-", - "A6684-", - "T6685-", - "A6686-", - "G6687-", - "T6688-", - "G6689-", - "T6690-", - "G6691-", - "G6692-", - "C6693-", - "T6694-", - "A6695-", - "A6696-", - "A6697-", - "T6698-", - "G6699-", - "G6700-", - "T6701-", - "A6702-", - "C6703-", - "T6704-", - "G6705-", - "T6706-", - "T6707-", - "A6708-", - "A6709-", - "T6710-", - "A6711-", - "A6712-", - "G6713-", - "T6714-", - "T6715-", - "T6716-", - "A6717-", - "T6718-", - "A6719-", - "G6720-", - "A6721-", - "C6722-", - "A6723-", - "A6724-", - "T6725-", - "A6726-", - "T6727-", - "C6728-", - "A6729-", - "T6730-", - "A6731-", - "G6732-", - "T6733-", - "A6734-", - "T6735-", - "T6736-", - "T6737-", - "T6738-", - "C6739-", - "T6740-", - "T6741-", - "T6742-", - "C6743-", - "C6744-", - "A6745-", - "G6746-", - "A6747-", - "A6748-", - "T6749-", - "T6750-", - "A6751-", - "G6752-", - "A6753-", - "T6754-", - "T6755-", - "A6756-", - "T6757-", - "T6758-", - "T6759-", - "T6760-", - "T6761-", - "T6762-", - "T6763-", - "A6764-", - "A6765-", - "A6766-", - "T6767-", - "A6768-", - "C6769-", - "T6770-", - "G6771-", - "A6772-", - "T6773-", - "C6774-", - "C6775-", - "T6776-", - "C6777-", - "A6778-", - "C6779-", - "A6780-", - "A6781-", - "T6782-", - "T6783-", - "C6784-", - "C6785-", - "G6786-", - "T6787-", - "G6788-", - "A6789-", - "T6790-", - "G6791-", - "T6792-", - "A6793-", - "G6794-", - "C6795-", - "A6796-", - "G6797-", - "T6798-", - "A6799-", - "G6800-", - "T6801-", - "T6802-", - "G6803-", - "G6804-", - "T6805-", - "G6806-", - "C6807-", - "A6808-", - "T6809-", - "G6810-", - "G6811-", - "T6812-", - "C6813-", - "T6814-", - "A6815-", - "T6816-", - "A6817-", - "T6818-", - "C6819-", - "G6820-", - "T6821-", - "T6822-", - "A6823-", - "A6824-", - "A6825-", - "A6826-", - "T6827-", - "G6828-", - "T6829-", - "A6830-", - "T6831-", - "C6832-", - "A6833-", - "T6834-", - "A6835-", - "T6836-", - "A6837-", - "T6838-", - "A6839-", - "A6840-", - "T6841-", - "A6842-", - "G6843-", - "T6844-", - "T6845-", - "T6846-", - "T6847-", - "C6848-", - "T6849-", - "G6850-", - "A6851-", - "C6852-", - "G6853-", - "T6854-", - "G6855-", - "G6856-", - "A6857-", - "G6858-", - "T6859-", - "A6860-", - "C6861-", - "A6862-", - "G6863-", - "A6864-", - "A6865-", - "T6866-", - "T6867-", - "T6868-", - "T6869-", - "C6870-", - "G6871-", - "A6872-", - "T6873-", - "T6874-", - "A6875-", - "A6876-", - "T6877-", - "G6878-", - "A6879-", - "G6880-", - "T6881-", - "T6882-", - "C6883-", - "A6884-", - "T6885-", - "G6886-", - "G6887-", - "T6888-", - "A6889-", - "A6890-", - "G6891-", - "G6892-", - "A6893-", - "A6894-", - "G6895-", - "G6896-", - "G6897-", - "C6898-", - "A6899-", - "A6900-", - "A6901-", - "T6902-", - "G6903-", - "C6904-", - "C6905-", - "T6906-", - "G6907-", - "T6908-", - "A6909-", - "T6910-", - "A6911-", - "T6912-", - "A6913-", - "A6914-", - "T6915-", - "A6916-", - "T6917-", - "A6918-", - "C6919-", - "A6920-", - "T6921-", - "A6922-", - "A6923-", - "G6924-", - "T6925-", - "T6926-", - "A6927-", - "A6928-", - "T6929-", - "A6930-", - "G6931-", - "T6932-", - "T6933-", - "T6934-", - "T6935-", - "T6936-", - "T6937-", - "A6938-", - "T6939-", - "C6940-", - "A6941-", - "T6942-", - "A6943-", - "T6944-", - "T6945-", - "T6946-", - "T6947-", - "C6948-", - "T6949-", - "A6950-", - "A6951-", - "T6952-", - "A6953-", - "C6954-", - "C6955-", - "A6956-", - "T6957-", - "A6958-", - "A6959-", - "T6960-", - "A6961-", - "A6962-", - "A6963-", - "A6964-", - "A6965-", - "T6966-", - "T6967-", - "A6968-", - "T6969-", - "C6970-", - "A6971-", - "T6972-", - "T6973-", - "A6974-", - "T6975-", - "T6976-", - "G6977-", - "C6978-", - "G6979-", - "T6980-", - "T6981-", - "T6982-", - "G6983-", - "G6984-", - "T6985-", - "A6986-", - "G6987-", - "T6988-", - "T6989-", - "C6990-", - "T6991-", - "G6992-", - "C6993-", - "C6994-", - "C6995-", - "T6996-", - "A6997-", - "T6998-", - "C6999-", - "A7000-", - "T7001-", - "C7002-", - "T7003-", - "A7004-", - "T7005-", - "A7006-", - "T7007-", - "C7008-", - "A7009-", - "C7010-", - "T7011-", - "G7012-", - "T7013-", - "C7014-", - "A7015-", - "C7016-", - "T7017-", - "C7018-", - "T7019-", - "C7020-", - "G7021-", - "C7022-", - "T7023-", - "C7024-", - "T7025-", - "C7026-", - "A7027-", - "C7028-", - "T7029-", - "A7030-", - "T7031-", - "A7032-", - "T7033-", - "C7034-", - "T7035-", - "T7036-", - "C7037-", - "T7038-", - "A7039-", - "A7040-", - "A7041-", - "A7042-", - "T7043-", - "T7044-", - "A7045-", - "C7046-", - "A7047-", - "A7048-", - "A7049-", - "C7050-", - "A7051-", - "A7052-", - "C7053-", - "T7054-", - "G7055-", - "G7056-", - "A7057-", - "T7058-", - "A7059-", - "T7060-", - "T7061-", - "C7062-", - "G7063-", - "A7064-", - "T7065-", - "A7066-", - "A7067-", - "C7068-", - "A7069-", - "G7070-", - "C7071-", - "A7072-", - "T7073-", - "T7074-", - "T7075-", - "G7076-", - "T7077-", - "G7078-", - "T7079-", - "A7080-", - "G7081-", - "T7082-", - "T7083-", - "T7084-", - "T7085-", - "T7086-", - "G7087-", - "T7088-", - "C7089-", - "T7090-", - "T7091-", - "T7092-", - "T7093-", - "A7094-", - "C7095-", - "A7096-", - "G7097-", - "T7098-", - "A7099-", - "T7100-", - "A7101-", - "T7102-", - "A7103-", - "C7104-", - "G7105-", - "T7106-", - "T7107-", - "A7108-", - "T7109-", - "T7110-", - "G7111-", - "T7112-", - "C7113-", - "A7114-", - "A7115-", - "A7116-", - "A7117-", - "T7118-", - "C7119-", - "T7120-", - "A7121-", - "A7122-", - "A7123-", - "C7124-", - "A7125-", - "A7126-", - "A7127-", - "T7128-", - "A7129-", - "T7130-", - "T7131-", - "A7132-", - "G7133-", - "C7134-", - "A7135-", - "T7136-", - "A7137-", - "A7138-", - "T7139-", - "A7140-", - "C7141-", - "A7142-", - "T7143-", - "C7144-", - "T7145-", - "A7146-", - "T7147-", - "C7148-", - "T7149-", - "A7150-", - "T7151-", - "A7152-", - "A7153-", - "G7154-", - "A7155-", - "T7156-", - "C7157-", - "A7158-", - "G7159-", - "G7160-", - "A7161-", - "T7162-", - "C7163-", - "C7164-", - "A7165-", - "T7166-", - "G7167-", - "T7168-", - "T7169-", - "C7170-", - "G7171-", - "A7172-", - "G7173-", - "C7174-", - "A7175-", - "T7176-", - "A7177-", - "C7178-", - "T7179-", - "A7180-", - "G7181-", - "C7182-", - "C7183-", - "A7184-", - "T7185-", - "G7186-", - "T7187-", - "A7188-", - "T7189-", - "A7190-", - "T7191-", - "T7192-", - "T7193-", - "G7194-", - "T7195-", - "A7196-", - "A7197-", - "C7198-", - "T7199-", - "T7200-", - "C7201-", - "G7202-", - "T7203-", - "C7204-", - "G7205-", - "T7206-", - "A7207-", - "C7208-", - "A7209-", - "G7210-", - "C7211-", - "G7212-", - "T7213-", - "T7214-", - "A7215-", - "G7216-", - "A7217-", - "T7218-", - "C7219-", - "A7220-", - "A7221-", - "T7222-", - "A7223-", - "G7224-", - "A7225-", - "A7226-", - "T7227-", - "A7228-", - "A7229-", - "A7230-", - "C7231-", - "A7232-", - "A7233-", - "T7234-", - "C7235-", - "G7236-", - "T7237-", - "G7238-", - "T7239-", - "G7240-", - "A7241-", - "C7242-", - "G7243-", - "C7244-", - "A7245-", - "A7246-", - "C7247-", - "T7248-", - "T7249-", - "T7250-", - "T7251-", - "T7252-", - "T7253-", - "A7254-", - "C7255-", - "G7256-", - "A7257-", - "T7258-", - "C7259-", - "T7260-", - "A7261-", - "G7262-", - "T7263-", - "T7264-", - "G7265-", - "T7266-", - "A7267-", - "T7268-", - "G7269-", - "A7270-", - "G7271-", - "T7272-", - "T7273-", - "T7274-", - "A7275-", - "T7276-", - "C7277-", - "G7278-", - "T7279-", - "T7280-", - "T7281-", - "A7282-", - "C7283-", - "A7284-", - "T7285-", - "A7286-", - "A7287-", - "G7288-", - "C7289-", - "A7290-", - "A7291-", - "T7292-", - "T7293-", - "A7294-", - "A7295-", - "C7296-", - "G7297-", - "G7298-", - "C7299-", - "T7300-", - "T7301-", - "T7302-", - "A7303-", - "A7304-", - "C7305-", - "A7306-", - "G7307-", - "A7308-", - "T7309-", - "G7310-", - "A7311-", - "T7312-", - "C7313-", - "T7314-", - "G7315-", - "A7316-", - "G7317-", - "T7318-", - "A7319-", - "A7320-", - "T7321-", - "A7322-", - "A7323-", - "T7324-", - "A7325-", - "T7326-", - "A7327-", - "C7328-", - "C7329-", - "T7330-", - "C7331-", - "T7332-", - "G7333-", - "T7334-", - "T7335-", - "A7336-", - "T7337-", - "A7338-", - "C7339-", - "G7340-", - "T7341-", - "T7342-", - "T7343-", - "A7344-", - "A7345-", - "T7346-", - "G7347-", - "T7348-", - "T7349-", - "C7350-", - "A7351-", - "C7352-", - "G7353-", - "G7354-", - "T7355-", - "C7356-", - "T7357-", - "T7358-", - "A7359-", - "G7360-", - "T7361-", - "A7362-", - "T7363-", - "T7364-", - "T7365-", - "T7366-", - "T7367-", - "A7368-", - "G7369-", - "A7370-", - "T7371-", - "A7372-", - "T7373-", - "C7374-", - "A7375-", - "A7376-", - "T7377-", - "T7378-", - "G7379-", - "T7380-", - "G7381-", - "A7382-", - "T7383-", - "T7384-", - "T7385-", - "A7386-", - "C7387-", - "A7388-", - "C7389-", - "C7390-", - "A7391-", - "T7392-", - "A7393-", - "T7394-", - "T7395-", - "C7396-", - "G7397-", - "A7398-", - "C7399-", - "T7400-", - "C7401-", - "C7402-", - "C7403-", - "T7404-", - "T7405-", - "G7406-", - "T7407-", - "G7408-", - "T7409-", - "G7410-", - "T7411-", - "A7412-", - "A7413-", - "C7414-", - "G7415-", - "T7416-", - "T7417-", - "A7418-", - "G7419-", - "A7420-", - "A7421-", - "A7422-", - "T7423-", - "T7424-", - "C7425-", - "T7426-", - "A7427-", - "A7428-", - "A7429-", - "T7430-", - "C7431-", - "T7432-", - "A7433-", - "T7434-", - "A7435-", - "T7436-", - "T7437-", - "A7438-", - "T7439-", - "C7440-", - "T7441-", - "A7442-", - "T7443-", - "T7444-", - "A7445-", - "C7446-", - "A7447-", - "G7448-", - "C7449-", - "G7450-", - "T7451-", - "A7452-", - "A7453-", - "A7454-", - "A7455-", - "C7456-", - "A7457-", - "C7458-", - "A7459-", - "T7460-", - "T7461-", - "C7462-", - "A7463-", - "A7464-", - "T7465-", - "A7466-", - "T7467-", - "T7468-", - "G7469-", - "T7470-", - "A7471-", - "T7472-", - "T7473-", - "G7474-", - "T7475-", - "T7476-", - "A7477-", - "T7478-", - "T7479-", - "T7480-", - "T7481-", - "T7482-", - "A7483-", - "T7484-", - "A7485-", - "T7486-", - "T7487-", - "A7488-", - "T7489-", - "T7490-", - "T7491-", - "A7492-", - "C7493-", - "A7494-", - "C7495-", - "A7496-", - "A7497-", - "T7498-", - "T7499-", - "A7500-", - "A7501-", - "C7502-", - "A7503-", - "A7504-", - "T7505-", - "G7506-", - "T7507-", - "A7508-", - "T7509-", - "T7510-", - "A7511-", - "T7512-", - "T7513-", - "A7514-", - "G7515-", - "T7516-", - "T7517-", - "T7518-", - "A7519-", - "T7520-", - "A7521-", - "T7522-", - "T7523-", - "A7524-", - "C7525-", - "T7526-", - "G7527-", - "A7528-", - "A7529-", - "T7530-", - "T7531-", - "A7532-", - "A7533-", - "T7534-", - "A7535-", - "A7536-", - "T7537-", - "A7538-", - "T7539-", - "A7540-", - "A7541-", - "A7542-", - "A7543-", - "T7544-", - "T7545-", - "C7546-", - "C7547-", - "C7548-", - "A7549-", - "A7550-", - "T7551-", - "C7552-", - "T7553-", - "T7554-", - "G7555-", - "T7556-", - "C7557-", - "A7558-", - "T7559-", - "A7560-", - "A7561-", - "A7562-", - "C7563-", - "A7564-", - "C7565-", - "A7566-", - "A7567-", - "A7568-", - "A7569-", - "T7570-", - "C7571-", - "C7572-", - "A7573-", - "T7574-", - "T7575-", - "A7576-", - "A7577-", - "A7578-", - "A7579-", - "A7580-", - "T7581-", - "G7582-", - "T7583-", - "C7584-", - "G7585-", - "A7586-", - "T7587-", - "A7588-", - "A7589-", - "A7590-", - "A7591-", - "T7592-", - "A7593-", - "T7594-", - "C7595-", - "T7596-", - "G7597-", - "A7598-", - "T7599-", - "G7600-", - "T7601-", - "T7602-", - "G7603-", - "T7604-", - "T7605-", - "G7606-", - "T7607-", - "T7608-", - "C7609-", - "G7610-", - "C7611-", - "T7612-", - "G7613-", - "C7614-", - "T7615-", - "A7616-", - "T7617-", - "G7618-", - "A7619-", - "T7620-", - "A7621-", - "A7622-", - "T7623-", - "C7624-", - "A7625-", - "G7626-", - "A7627-", - "T7628-", - "C7629-", - "A7630-", - "T7631-", - "T7632-", - "A7633-", - "G7634-", - "C7635-", - "C7636-", - "G7637-", - "A7638-", - "T7639-", - "A7640-", - "G7641-", - "T7642-", - "G7643-", - "G7644-", - "T7645-", - "A7646-", - "A7647-", - "T7648-", - "G7649-", - "C7650-", - "T7651-", - "A7652-", - "T7653-", - "C7654-", - "G7655-", - "A7656-", - "A7657-", - "A7658-", - "C7659-", - "A7660-", - "A7661-", - "C7662-", - "A7663-", - "T7664-", - "C7665-", - "G7666-", - "C7667-", - "C7668-", - "A7669-", - "G7670-", - "A7671-", - "A7672-", - "A7673-", - "T7674-", - "T7675-", - "A7676-", - "C7677-", - "A7678-", - "A7679-", - "A7680-", - "C7681-", - "G7682-", - "C7683-", - "T7684-", - "A7685-", - "C7686-", - "A7687-", - "A7688-", - "C7689-", - "A7690-", - "G7691-", - "A7692-", - "T7693-", - "A7694-", - "T7695-", - "T7696-", - "C7697-", - "C7698-", - "A7699-", - "G7700-", - "C7701-", - "T7702-", - "A7703-", - "T7704-", - "C7705-", - "A7706-", - "G7707-", - "A7708-", - "T7709-", - "T7710-", - "A7711-", - "T7712-", - "G7713-", - "T7714-", - "G7715-", - "G7716-", - "T7717-", - "C7718-", - "C7719-", - "A7720-", - "G7721-", - "A7722-", - "G7723-", - "G7724-", - "G7725-", - "A7726-", - "G7727-", - "A7728-", - "T7729-", - "G7730-", - "G7731-", - "A7732-", - "T7733-", - "A7734-", - "T7735-", - "T7736-", - "G7737-", - "T7738-", - "T7739-", - "T7740-", - "A7741-", - "C7742-", - "A7743-", - "C7744-", - "G7745-", - "G7746-", - "T7747-", - "G7748-", - "A7749-", - "C7750-", - "T7751-", - "G7752-", - "T7753-", - "A7754-", - "T7755-", - "C7756-", - "C7757-", - "A7758-", - "C7759-", - "G7760-", - "C7761-", - "T7762-", - "A7763-", - "G7764-", - "A7765-", - "G7766-", - "A7767-", - "T7768-", - "A7769-", - "T7770-", - "C7771-", - "G7772-", - "A7773-", - "C7774-", - "G7775-", - "G7776-", - "T7777-", - "A7778-", - "T7779-", - "G7780-", - "T7781-", - "A7782-", - "T7783-", - "T7784-", - "G7785-", - "T7786-", - "A7787-", - "G7788-", - "A7789-", - "T7790-", - "G7791-", - "C7792-", - "T7793-", - "C7794-", - "T7795-", - "C7796-", - "A7797-", - "T7798-", - "G7799-", - "G7800-", - "T7801-", - "T7802-", - "A7803-", - "T7804-", - "A7805-", - "C7806-", - "A7807-", - "G7808-", - "G7809-", - "T7810-", - "A7811-", - "T7812-", - "T7813-", - "A7814-", - "G7815-", - "A7816-", - "T7817-", - "G7818-", - "T7819-", - "C7820-", - "A7821-", - "G7822-", - "C7823-", - "A7824-", - "T7825-", - "G7826-", - "T7827-", - "A7828-", - "G7829-", - "T7830-", - "A7831-", - "T7832-", - "T7833-", - "A7834-", - "G7835-", - "T7836-", - "A7837-", - "G7838-", - "A7839-", - "C7840-", - "T7841-", - "A7842-", - "T7843-", - "C7844-", - "A7845-", - "A7846-", - "C7847-", - "G7848-", - "T7849-", - "T7850-", - "C7851-", - "A7852-", - "G7853-", - "G7854-", - "A7855-", - "A7856-", - "A7857-", - "A7858-", - "C7859-", - "C7860-", - "A7861-", - "G7862-", - "A7863-", - "C7864-", - "A7865-", - "C7866-", - "T7867-", - "A7868-", - "C7869-", - "A7870-", - "A7871-", - "C7872-", - "A7873-", - "T7874-", - "C7875-", - "A7876-", - "T7877-", - "A7878-", - "T7879-", - "A7880-", - "T7881-", - "C7882-", - "C7883-", - "C7884-", - "A7885-", - "T7886-", - "C7887-", - "T7888-", - "C7889-", - "T7890-", - "A7891-", - "G7892-", - "G7893-", - "T7894-", - "A7895-", - "T7896-", - "T7897-", - "G7898-", - "T7899-", - "G7900-", - "C7901-", - "T7902-", - "T7903-", - "G7904-", - "T7905-", - "A7906-", - "T7907-", - "T7908-", - "A7909-", - "G7910-", - "T7911-", - "A7912-", - "G7913-", - "G7914-", - "C7915-", - "A7916-", - "T7917-", - "T7918-", - "A7919-", - "T7920-", - "T7921-", - "A7922-", - "T7923-", - "T7924-", - "A7925-", - "C7926-", - "G7927-", - "T7928-", - "G7929-", - "T7930-", - "T7931-", - "G7932-", - "T7933-", - "C7934-", - "T7935-", - "A7936-", - "T7937-", - "T7938-", - "A7939-", - "T7940-", - "C7941-", - "T7942-", - "G7943-", - "T7944-", - "T7945-", - "T7946-", - "A7947-", - "T7948-", - "A7949-", - "T7950-", - "G7951-", - "T7952-", - "T7953-", - "C7954-", - "A7955-", - "C7956-", - "T7957-", - "C7958-", - "G7959-", - "A7960-", - "A7961-", - "G7962-", - "A7963-", - "A7964-", - "C7965-", - "T7966-", - "A7967-", - "A7968-", - "A7969-", - "C7970-", - "T7971-", - "A7972-", - "C7973-", - "C7974-", - "T7975-", - "A7976-", - "T7977-", - "A7978-", - "C7979-", - "A7980-", - "A7981-", - "G7982-", - "A7983-", - "T7984-", - "A7985-", - "T7986-", - "G7987-", - "G7988-", - "T7989-", - "T7990-", - "G7991-", - "T7992-", - "G7993-", - "T7994-", - "T7995-", - "A7996-", - "T7997-", - "A7998-", - "T7999-", - "T8000-", - "T8001-", - "T8002-", - "T8003-", - "T8004-", - "A8005-", - "T8006-", - "A8007-", - "A8008-", - "A8009-", - "A8010-", - "T8011-", - "T8012-", - "T8013-", - "T8014-", - "T8015-", - "T8016-", - "T8017-", - "A8018-", - "T8019-", - "G8020-", - "A8021-", - "G8022-", - "T8023-", - "A8024-", - "T8025-", - "T8026-", - "T8027-", - "T8028-", - "T8029-", - "A8030-", - "C8031-", - "A8032-", - "A8033-", - "A8034-", - "A8035-", - "A8036-", - "T8037-", - "G8038-", - "T8039-", - "A8040-", - "T8041-", - "A8042-", - "T8043-", - "G8044-", - "T8045-", - "A8046-", - "T8047-", - "A8048-", - "A8049-", - "A8050-", - "A8051-", - "A8052-", - "A8053-", - "A8054-", - "A8055-", - "T8056-", - "A8057-", - "C8058-", - "T8059-", - "A8060-", - "A8061-", - "G8062-", - "T8063-", - "A8064-", - "T8065-", - "A8066-", - "C8067-", - "G8068-", - "A8069-", - "T8070-", - "G8071-", - "T8072-", - "A8073-", - "T8074-", - "C8075-", - "C8076-", - "T8077-", - "G8078-", - "T8079-", - "A8080-", - "T8081-", - "T8082-", - "A8083-", - "T8084-", - "T8085-", - "T8086-", - "G8087-", - "T8088-", - "A8089-", - "T8090-", - "T8091-", - "T8092-", - "A8093-", - "T8094-", - "C8095-", - "T8096-", - "A8097-", - "A8098-", - "A8099-", - "C8100-", - "A8101-", - "A8102-", - "T8103-", - "A8104-", - "C8105-", - "T8106-", - "T8107-", - "C8108-", - "T8109-", - "G8110-", - "C8111-", - "C8112-", - "T8113-", - "C8114-", - "T8115-", - "A8116-", - "G8117-", - "A8118-", - "T8119-", - "G8120-", - "G8121-", - "G8122-", - "A8123-", - "T8124-", - "A8125-", - "C8126-", - "A8127-", - "A8128-", - "A8129-", - "A8130-", - "A8131-", - "T8132-", - "T8133-", - "T8134-", - "T8135-", - "T8136-", - "T8137-", - "A8138-", - "T8139-", - "T8140-", - "T8141-", - "C8142-", - "A8143-", - "G8144-", - "C8145-", - "A8146-", - "T8147-", - "A8148-", - "T8149-", - "T8150-", - "A8151-", - "A8152-", - "A8153-", - "G8154-", - "T8155-", - "A8156-", - "A8157-", - "A8158-", - "A8159-", - "T8160-", - "C8161-", - "T8162-", - "A8163-", - "G8164-", - "T8165-", - "T8166-", - "A8167-", - "C8168-", - "C8169-", - "T8170-", - "T8171-", - "G8172-", - "A8173-", - "A8174-", - "A8175-", - "A8176-", - "T8177-", - "G8178-", - "A8179-", - "A8180-", - "T8181-", - "A8182-", - "C8183-", - "A8184-", - "G8185-", - "T8186-", - "G8187-", - "G8188-", - "G8189-", - "T8190-", - "G8191-", - "G8192-", - "T8193-", - "T8194-", - "C8195-", - "C8196-", - "G8197-", - "T8198-", - "A8199-", - "T8200-", - "C8201-", - "A8202-", - "C8203-", - "C8204-", - "A8205-", - "G8206-", - "T8207-", - "A8208-", - "A8209-", - "G8210-", - "A8211-", - "A8212-", - "C8213-", - "A8214-", - "T8215-", - "A8216-", - "A8217-", - "T8218-", - "A8219-", - "G8220-", - "T8221-", - "C8222-", - "G8223-", - "A8224-", - "A8225-", - "T8226-", - "A8227-", - "C8228-", - "A8229-", - "G8230-", - "T8231-", - "A8232-", - "T8233-", - "C8234-", - "C8235-", - "G8236-", - "A8237-", - "T8238-", - "T8239-", - "G8240-", - "A8241-", - "G8242-", - "A8243-", - "T8244-", - "T8245-", - "T8246-", - "T8247-", - "G8248-", - "C8249-", - "A8250-", - "T8251-", - "A8252-", - "C8253-", - "A8254-", - "A8255-", - "T8256-", - "A8257-", - "C8258-", - "T8259-", - "A8260-", - "G8261-", - "T8262-", - "C8263-", - "T8264-", - "A8265-", - "G8266-", - "A8267-", - "A8268-", - "A8269-", - "G8270-", - "A8271-", - "A8272-", - "A8273-", - "T8274-", - "T8275-", - "T8276-", - "G8277-", - "T8278-", - "A8279-", - "A8280-", - "T8281-", - "C8282-", - "A8283-", - "T8284-", - "C8285-", - "C8286-", - "T8287-", - "C8288-", - "T8289-", - "G8290-", - "T8291-", - "G8292-", - "A8293-", - "C8294-", - "A8295-", - "G8296-", - "G8297-", - "A8298-", - "G8299-", - "T8300-", - "C8301-", - "C8302-", - "A8303-", - "T8304-", - "A8305-", - "T8306-", - "A8307-", - "T8308-", - "C8309-", - "T8310-", - "G8311-", - "T8312-", - "A8313-", - "T8314-", - "C8315-", - "A8316-", - "T8317-", - "C8318-", - "G8319-", - "T8320-", - "C8321-", - "T8322-", - "A8323-", - "G8324-", - "T8325-", - "T8326-", - "T8327-", - "T8328-", - "T8329-", - "A8330-", - "T8331-", - "C8332-", - "A8333-", - "G8334-", - "T8335-", - "G8336-", - "T8337-", - "C8338-", - "C8339-", - "T8340-", - "A8341-", - "T8342-", - "G8343-", - "C8344-", - "T8345-", - "A8346-", - "T8347-", - "A8348-", - "T8349-", - "T8350-", - "C8351-", - "C8352-", - "T8353-", - "G8354-", - "T8355-", - "T8356-", - "A8357-", - "T8358-", - "C8359-", - "A8360-", - "T8361-", - "C8362-", - "A8363-", - "T8364-", - "T8365-", - "A8366-", - "G8367-", - "T8368-", - "T8369-", - "A8370-", - "A8371-", - "T8372-", - "G8373-", - "A8374-", - "A8375-", - "A8376-", - "A8377-", - "T8378-", - "A8379-", - "A8380-", - "C8381-", - "T8382-", - "C8383-", - "T8384-", - "C8385-", - "G8386-", - "T8387-", - "G8388-", - "C8389-", - "T8390-", - "T8391-", - "C8392-", - "A8393-", - "G8394-", - "A8395-", - "A8396-", - "A8397-", - "A8398-", - "G8399-", - "T8400-", - "C8401-", - "A8402-", - "A8403-", - "A8404-", - "T8405-", - "A8406-", - "T8407-", - "T8408-", - "G8409-", - "T8410-", - "A8411-", - "T8412-", - "C8413-", - "C8414-", - "A8415-", - "T8416-", - "A8417-", - "C8418-", - "A8419-", - "T8420-", - "A8421-", - "T8422-", - "A8423-", - "T8424-", - "C8425-", - "T8426-", - "C8427-", - "C8428-", - "A8429-", - "A8430-", - "A8431-", - "A8432-", - "C8433-", - "T8434-", - "A8435-", - "T8436-", - "C8437-", - "A8438-", - "C8439-", - "T8440-", - "T8441-", - "A8442-", - "T8443-", - "A8444-", - "C8445-", - "G8446-", - "T8447-", - "T8448-", - "T8449-", - "A8450-", - "T8451-", - "C8452-", - "T8453-", - "T8454-", - "T8455-", - "A8456-", - "A8457-", - "C8458-", - "G8459-", - "A8460-", - "A8461-", - "C8462-", - "A8463-", - "T8464-", - "A8465-", - "T8466-", - "A8467-", - "C8468-", - "C8469-", - "T8470-", - "A8471-", - "G8472-", - "A8473-", - "T8474-", - "G8475-", - "G8476-", - "T8477-", - "T8478-", - "A8479-", - "T8480-", - "T8481-", - "T8482-", - "A8483-", - "C8484-", - "T8485-", - "A8486-", - "A8487-", - "C8488-", - "A8489-", - "G8490-", - "A8491-", - "C8492-", - "A8493-", - "T8494-", - "T8495-", - "T8496-", - "T8497-", - "T8498-", - "T8499-", - "C8500-", - "A8501-", - "A8502-", - "G8503-", - "A8504-", - "T8505-", - "C8506-", - "T8507-", - "A8508-", - "T8509-", - "T8510-", - "G8511-", - "A8512-", - "C8513-", - "A8514-", - "A8515-", - "T8516-", - "A8517-", - "A8518-", - "C8519-", - "T8520-", - "C8521-", - "C8522-", - "T8523-", - "A8524-", - "T8525-", - "A8526-", - "G8527-", - "T8528-", - "T8529-", - "T8530-", - "C8531-", - "C8532-", - "A8533-", - "C8534-", - "A8535-", - "T8536-", - "C8537-", - "A8538-", - "A8539-", - "C8540-", - "C8541-", - "A8542-", - "A8543-", - "G8544-", - "T8545-", - "A8546-", - "A8547-", - "T8548-", - "G8549-", - "A8550-", - "T8551-", - "C8552-", - "A8553-", - "T8554-", - "C8555-", - "T8556-", - "A8557-", - "T8558-", - "T8559-", - "G8560-", - "T8561-", - "T8562-", - "A8563-", - "T8564-", - "A8565-", - "T8566-", - "A8567-", - "A8568-", - "C8569-", - "A8570-", - "A8571-", - "T8572-", - "A8573-", - "A8574-", - "C8575-", - "A8576-", - "T8577-", - "A8578-", - "A8579-", - "C8580-", - "T8581-", - "C8582-", - "T8583-", - "T8584-", - "T8585-", - "T8586-", - "C8587-", - "C8588-", - "A8589-", - "T8590-", - "T8591-", - "T8592-", - "T8593-", - "T8594-", - "A8595-", - "T8596-", - "C8597-", - "A8598-", - "G8599-", - "T8600-", - "A8601-", - "T8602-", - "C8603-", - "T8604-", - "A8605-", - "T8606-", - "A8607-", - "T8608-", - "C8609-", - "A8610-", - "A8611-", - "C8612-", - "G8613-", - "T8614-", - "C8615-", - "G8616-", - "T8617-", - "T8618-", - "G8619-", - "T8620-", - "A8621-", - "G8622-", - "T8623-", - "G8624-", - "A8625-", - "A8626-", - "T8627-", - "A8628-", - "G8629-", - "T8630-", - "A8631-", - "G8632-", - "T8633-", - "C8634-", - "A8635-", - "T8636-", - "T8637-", - "G8638-", - "A8639-", - "T8640-", - "C8641-", - "T8642-", - "A8643-", - "T8644-", - "T8645-", - "A8646-", - "T8647-", - "A8648-", - "T8649-", - "G8650-", - "A8651-", - "A8652-", - "A8653-", - "C8654-", - "G8655-", - "G8656-", - "A8657-", - "T8658-", - "A8659-", - "T8660-", - "G8661-", - "T8662-", - "C8663-", - "T8664-", - "A8665-", - "G8666-", - "T8667-", - "T8668-", - "A8669-", - "A8670-", - "T8671-", - "A8672-", - "T8673-", - "T8674-", - "T8675-", - "T8676-", - "C8677-", - "T8678-", - "T8679-", - "T8680-", - "G8681-", - "A8682-", - "T8683-", - "T8684-", - "T8685-", - "A8686-", - "A8687-", - "A8688-", - "G8689-", - "T8690-", - "C8691-", - "T8692-", - "A8693-", - "T8694-", - "A8695-", - "G8696-", - "T8697-", - "C8698-", - "T8699-", - "T8700-", - "T8701-", - "A8702-", - "C8703-", - "A8704-", - "A8705-", - "A8706-", - "C8707-", - "A8708-", - "T8709-", - "A8710-", - "A8711-", - "T8712-", - "A8713-", - "T8714-", - "C8715-", - "C8716-", - "T8717-", - "T8718-", - "A8719-", - "T8720-", - "C8721-", - "C8722-", - "G8723-", - "A8724-", - "C8725-", - "T8726-", - "T8727-", - "T8728-", - "A8729-", - "T8730-", - "A8731-", - "T8732-", - "T8733-", - "T8734-", - "C8735-", - "C8736-", - "T8737-", - "G8738-", - "T8739-", - "A8740-", - "G8741-", - "G8742-", - "G8743-", - "T8744-", - "G8745-", - "G8746-", - "C8747-", - "A8748-", - "T8749-", - "A8750-", - "A8751-", - "T8752-", - "T8753-", - "T8754-", - "T8755-", - "A8756-", - "T8757-", - "T8758-", - "C8759-", - "T8760-", - "G8761-", - "C8762-", - "C8763-", - "T8764-", - "C8765-", - "C8766-", - "A8767-", - "C8768-", - "A8769-", - "A8770-", - "T8771-", - "C8772-", - "A8773-", - "G8774-", - "T8775-", - "G8776-", - "T8777-", - "T8778-", - "T8779-", - "C8780-", - "C8781-", - "A8782-", - "A8783-", - "A8784-", - "T8785-", - "A8786-", - "T8787-", - "A8788-", - "T8789-", - "T8790-", - "A8791-", - "C8792-", - "T8793-", - "A8794-", - "G8795-", - "A8796-", - "C8797-", - "A8798-", - "A8799-", - "T8800-", - "A8801-", - "T8802-", - "T8803-", - "C8804-", - "C8805-", - "A8806-", - "T8807-", - "A8808-", - "T8809-", - "A8810-", - "G8811-", - "T8812-", - "T8813-", - "A8814-", - "T8815-", - "T8816-", - "A8817-", - "G8818-", - "T8819-", - "T8820-", - "A8821-", - "A8822-", - "G8823-", - "G8824-", - "G8825-", - "A8826-", - "C8827-", - "C8828-", - "C8829-", - "A8830-", - "A8831-", - "T8832-", - "T8833-", - "A8834-", - "G8835-", - "A8836-", - "A8837-", - "C8838-", - "A8839-", - "C8840-", - "G8841-", - "T8842-", - "A8843-", - "C8844-", - "G8845-", - "C8846-", - "G8847-", - "C8848-", - "T8849-", - "T8850-", - "A8851-", - "T8852-", - "T8853-", - "C8854-", - "A8855-", - "T8856-", - "C8857-", - "A8858-", - "T8859-", - "T8860-", - "T8861-", - "G8862-", - "G8863-", - "A8864-", - "T8865-", - "C8866-", - "G8867-", - "T8868-", - "A8869-", - "T8870-", - "T8871-", - "T8872-", - "C8873-", - "A8874-", - "T8875-", - "A8876-", - "A8877-", - "A8878-", - "A8879-", - "G8880-", - "T8881-", - "T8882-", - "A8883-", - "T8884-", - "T8885-", - "A8886-", - "T8887-", - "G8888-", - "T8889-", - "T8890-", - "A8891-", - "T8892-", - "A8893-", - "G8894-", - "A8895-", - "T8896-", - "G8897-", - "T8898-", - "C8899-", - "A8900-", - "A8901-", - "C8902-", - "A8903-", - "C8904-", - "A8905-", - "T8906-", - "T8907-", - "C8908-", - "T8909-", - "A8910-", - "C8911-", - "A8912-", - "T8913-", - "T8914-", - "T8915-", - "T8916-", - "T8917-", - "T8918-", - "T8919-", - "A8920-", - "A8921-", - "T8922-", - "T8923-", - "G8924-", - "T8925-", - "C8926-", - "T8927-", - "A8928-", - "T8929-", - "A8930-", - "T8931-", - "A8932-", - "G8933-", - "T8934-", - "A8935-", - "T8936-", - "T8937-", - "T8938-", - "T8939-", - "T8940-", - "C8941-", - "T8942-", - "G8943-", - "A8944-", - "T8945-", - "A8946-", - "T8947-", - "T8948-", - "T8949-", - "T8950-", - "C8951-", - "T8952-", - "A8953-", - "T8954-", - "A8955-", - "A8956-", - "T8957-", - "A8958-", - "T8959-", - "C8960-", - "A8961-", - "G8962-", - "A8963-", - "A8964-", - "T8965-", - "T8966-", - "G8967-", - "T8968-", - "C8969-", - "T8970-", - "T8971-", - "C8972-", - "C8973-", - "A8974-", - "T8975-", - "A8976-", - "G8977-", - "G8978-", - "A8979-", - "A8980-", - "G8981-", - "T8982-", - "T8983-", - "G8984-", - "T8985-", - "A8986-", - "T8987-", - "A8988-", - "C8989-", - "T8990-", - "A8991-", - "T8992-", - "T8993-", - "C8994-", - "G8995-", - "G8996-", - "A8997-", - "A8998-", - "T8999-", - "C9000-", - "A9001-", - "G9002-", - "T9003-", - "T9004-", - "A9005-", - "C9006-", - "A9007-", - "T9008-", - "G9009-", - "T9010-", - "T9011-", - "T9012-", - "A9013-", - "A9014-", - "A9015-", - "T9016-", - "A9017-", - "A9018-", - "T9019-", - "T9020-", - "C9021-", - "T9022-", - "C9023-", - "T9024-", - "G9025-", - "A9026-", - "T9027-", - "G9028-", - "T9029-", - "C9030-", - "A9031-", - "T9032-", - "T9033-", - "C9034-", - "C9035-", - "T9036-", - "T9037-", - "A9038-", - "T9039-", - "A9040-", - "C9041-", - "A9042-", - "A9043-", - "T9044-", - "C9045-", - "A9046-", - "A9047-", - "A9048-", - "T9049-", - "T9050-", - "C9051-", - "A9052-", - "T9053-", - "T9054-", - "A9055-", - "T9056-", - "T9057-", - "A9058-", - "A9059-", - "A9060-", - "C9061-", - "A9062-", - "G9063-", - "T9064-", - "T9065-", - "T9066-", - "A9067-", - "A9068-", - "T9069-", - "A9070-", - "G9071-", - "T9072-", - "C9073-", - "T9074-", - "G9075-", - "T9076-", - "A9077-", - "G9078-", - "A9079-", - "C9080-", - "C9081-", - "T9082-", - "T9083-", - "T9084-", - "A9085-", - "T9086-", - "C9087-", - "G9088-", - "T9089-", - "C9090-", - "G9091-", - "T9092-", - "A9093-", - "C9094-", - "A9095-", - "T9096-", - "A9097-", - "T9098-", - "C9099-", - "C9100-", - "A9101-", - "T9102-", - "T9103-", - "G9104-", - "T9105-", - "C9106-", - "T9107-", - "T9108-", - "A9109-", - "T9110-", - "T9111-", - "A9112-", - "G9113-", - "T9114-", - "T9115-", - "A9116-", - "C9117-", - "G9118-", - "C9119-", - "T9120-", - "T9121-", - "A9122-", - "T9123-", - "T9124-", - "T9125-", - "T9126-", - "T9127-", - "A9128-", - "T9129-", - "G9130-", - "G9131-", - "G9132-", - "T9133-", - "T9134-", - "T9135-", - "T9136-", - "A9137-", - "C9138-", - "G9139-", - "T9140-", - "T9141-", - "G9142-", - "C9143-", - "T9144-", - "T9145-", - "T9146-", - "A9147-", - "T9148-", - "T9149-", - "A9150-", - "T9151-", - "A9152-", - "T9153-", - "T9154-", - "T9155-", - "T9156-", - "A9157-", - "T9158-", - "A9159-", - "A9160-", - "T9161-", - "A9162-", - "A9163-", - "T9164-", - "G9165-", - "A9166-", - "T9167-", - "T9168-", - "G9169-", - "T9170-", - "T9171-", - "T9172-", - "G9173-", - "A9174-", - "C9175-", - "A9176-", - "A9177-", - "T9178-", - "G9179-", - "T9180-", - "C9181-", - "G9182-", - "T9183-", - "A9184-", - "G9185-", - "T9186-", - "A9187-", - "T9188-", - "A9189-", - "G9190-", - "A9191-", - "T9192-", - "A9193-", - "T9194-", - "A9195-", - "T9196-", - "T9197-", - "A9198-", - "T9199-", - "T9200-", - "A9201-", - "G9202-", - "A9203-", - "G9204-", - "G9205-", - "A9206-", - "G9207-", - "G9208-", - "T9209-", - "A9210-", - "T9211-", - "A9212-", - "A9213-", - "T9214-", - "T9215-", - "A9216-", - "T9217-", - "A9218-", - "A9219-", - "A9220-", - "A9221-", - "A9222-", - "G9223-", - "T9224-", - "T9225-", - "T9226-", - "C9227-", - "T9228-", - "G9229-", - "A9230-", - "G9231-", - "T9232-", - "A9233-", - "C9234-", - "G9235-", - "A9236-", - "T9237-", - "G9238-", - "T9239-", - "T9240-", - "A9241-", - "T9242-", - "A9243-", - "A9244-", - "G9245-", - "A9246-", - "G9247-", - "G9248-", - "A9249-", - "G9250-", - "A9251-", - "G9252-", - "G9253-", - "A9254-", - "C9255-", - "A9256-", - "C9257-", - "A9258-", - "T9259-", - "T9260-", - "A9261-", - "A9262-", - "C9263-", - "A9264-", - "T9265-", - "C9266-", - "A9267-", - "T9268-", - "A9269-", - "C9270-", - "A9271-", - "T9272-", - "C9273-", - "A9274-", - "A9275-", - "T9276-", - "T9277-", - "A9278-", - "A9279-", - "C9280-", - "T9281-", - "A9282-", - "C9283-", - "A9284-", - "T9285-", - "T9286-", - "C9287-", - "T9288-", - "T9289-", - "A9290-", - "T9291-", - "A9292-", - "A9293-", - "C9294-", - "A9295-", - "T9296-", - "T9297-", - "G9298-", - "T9299-", - "A9300-", - "A9301-", - "T9302-", - "C9303-", - "A9304-", - "A9305-", - "A9306-", - "A9307-", - "G9308-", - "A9309-", - "A9310-", - "T9311-", - "T9312-", - "G9313-", - "C9314-", - "A9315-", - "A9316-", - "T9317-", - "T9318-", - "T9319-", - "T9320-", - "G9321-", - "A9322-", - "T9323-", - "G9324-", - "T9325-", - "A9326-", - "T9327-", - "A9328-", - "A9329-", - "C9330-", - "A9331-", - "A9332-", - "C9333-", - "T9334-", - "G9335-", - "T9336-", - "C9337-", - "A9338-", - "A9339-", - "T9340-", - "G9341-", - "G9342-", - "A9343-", - "A9344-", - "T9345-", - "T9346-", - "G9347-", - "T9348-", - "A9349-", - "T9350-", - "A9351-", - "T9352-", - "T9353-", - "A9354-", - "C9355-", - "A9356-", - "A9357-", - "A9358-", - "T9359-", - "T9360-", - "A9361-", - "C9362-", - "G9363-", - "G9364-", - "T9365-", - "A9366-", - "T9367-", - "G9368-", - "T9369-", - "T9370-", - "G9371-", - "T9372-", - "A9373-", - "A9374-", - "C9375-", - "A9376-", - "A9377-", - "C9378-", - "A9379-", - "A9380-", - "A9381-", - "T9382-", - "A9383-", - "C9384-", - "C9385-", - "G9386-", - "A9387-", - "T9388-", - "C9389-", - "G9390-", - "G9391-", - "T9392-", - "A9393-", - "A9394-", - "T9395-", - "T9396-", - "G9397-", - "T9398-", - "C9399-", - "T9400-", - "C9401-", - "T9402-", - "G9403-", - "C9404-", - "C9405-", - "G9406-", - "C9407-", - "T9408-", - "G9409-", - "T9410-", - "A9411-", - "A9412-", - "T9413-", - "A9414-", - "G9415-", - "A9416-", - "A9417-", - "T9418-", - "T9419-", - "A9420-", - "A9421-", - "T9422-", - "T9423-", - "A9424-", - "T9425-", - "A9426-", - "T9427-", - "A9428-", - "T9429-", - "C9430-", - "T9431-", - "A9432-", - "T9433-", - "T9434-", - "A9435-", - "C9436-", - "A9437-", - "C9438-", - "C9439-", - "G9440-", - "G9441-", - "C9442-", - "C9443-", - "T9444-", - "T9445-", - "G9446-", - "T9447-", - "A9448-", - "T9449-", - "C9450-", - "A9451-", - "T9452-", - "A9453-", - "A9454-", - "T9455-", - "A9456-", - "A9457-", - "A9458-", - "G9459-", - "T9460-", - "T9461-", - "G9462-", - "T9463-", - "G9464-", - "G9465-", - "T9466-", - "A9467-", - "G9468-", - "T9469-", - "A9470-", - "T9471-", - "G9472-", - "A9473-", - "T9474-", - "C9475-", - "T9476-", - "C9477-", - "C9478-", - "A9479-", - "T9480-", - "A9481-", - "T9482-", - "T9483-", - "T9484-", - "A9485-", - "T9486-", - "A9487-", - "A9488-", - "T9489-", - "T9490-", - "T9491-", - "A9492-", - "G9493-", - "T9494-", - "A9495-", - "C9496-", - "T9497-", - "T9498-", - "T9499-", - "G9500-", - "T9501-", - "A9502-", - "T9503-", - "T9504-", - "T9505-", - "A9506-", - "G9507-", - "T9508-", - "T9509-", - "T9510-", - "T9511-", - "T9512-", - "T9513-", - "T9514-", - "G9515-", - "G9516-", - "A9517-", - "A9518-", - "T9519-", - "C9520-", - "A9521-", - "T9522-", - "A9523-", - "A9524-", - "A9525-", - "A9526-", - "A9527-", - "A9528-", - "A9529-", - "G9530-", - "T9531-", - "T9532-", - "T9533-", - "T9534-", - "A9535-", - "C9536-", - "T9537-", - "A9538-", - "A9539-", - "T9540-", - "T9541-", - "T9542-", - "A9543-", - "A9544-", - "A9545-", - "A9546-", - "T9547-", - "T9548-", - "T9549-", - "A9550-", - "A9551-", - "A9552-", - "A9553-", - "A9554-", - "G9555-", - "T9556-", - "A9557-", - "T9558-", - "T9559-", - "T9560-", - "A9561-", - "C9562-", - "A9563-", - "T9564-", - "T9565-", - "T9566-", - "T9567-", - "T9568-", - "C9569-", - "A9570-", - "C9571-", - "T9572-", - "G9573-", - "T9574-", - "T9575-", - "T9576-", - "A9577-", - "G9578-", - "T9579-", - "C9580-", - "G9581-", - "C9582-", - "G9583-", - "G9584-", - "A9585-", - "T9586-", - "A9587-", - "T9588-", - "G9589-", - "G9590-", - "A9591-", - "A9592-", - "T9593-", - "T9594-", - "C9595-", - "G9596-", - "A9597-", - "T9598-", - "C9599-", - "C9600-", - "T9601-", - "G9602-", - "T9603-", - "C9604-", - "A9605-", - "A9606-", - "A9607-", - "A9608-", - "T9609-", - "C9610-", - "A9611-", - "A9612-", - "T9613-", - "A9614-", - "C9615-", - "A9616-", - "T9617-", - "C9618-", - "A9619-", - "T9620-", - "C9621-", - "T9622-", - "A9623-", - "T9624-", - "A9625-", - "G9626-", - "A9627-", - "T9628-", - "C9629-", - "A9630-", - "T9631-", - "G9632-", - "T9633-", - "A9634-", - "A9635-", - "C9636-", - "A9637-", - "A9638-", - "T9639-", - "A9640-", - "T9641-", - "T9642-", - "A9643-", - "C9644-", - "A9645-", - "A9646-", - "T9647-", - "A9648-", - "C9649-", - "A9650-", - "T9651-", - "A9652-", - "G9653-", - "A9654-", - "T9655-", - "G9656-", - "A9657-", - "A9658-", - "C9659-", - "C9660-", - "A9661-", - "A9662-", - "A9663-", - "T9664-", - "G9665-", - "A9666-", - "T9667-", - "A9668-", - "T9669-", - "A9670-", - "A9671-", - "G9672-", - "A9673-", - "C9674-", - "T9675-", - "A9676-", - "A9677-", - "C9678-", - "A9679-", - "G9680-", - "T9681-", - "A9682-", - "T9683-", - "G9684-", - "C9685-", - "A9686-", - "T9687-", - "T9688-", - "A9689-", - "T9690-", - "C9691-", - "C9692-", - "G9693-", - "A9694-", - "A9695-", - "A9696-", - "T9697-", - "G9698-", - "T9699-", - "T9700-", - "A9701-", - "A9702-", - "T9703-", - "A9704-", - "A9705-", - "C9706-", - "A9707-", - "T9708-", - "T9709-", - "A9710-", - "C9711-", - "A9712-", - "T9713-", - "A9714-", - "T9715-", - "T9716-", - "A9717-", - "T9718-", - "A9719-", - "T9720-", - "C9721-", - "A9722-", - "A9723-", - "T9724-", - "A9725-", - "T9726-", - "C9727-", - "A9728-", - "C9729-", - "A9730-", - "A9731-", - "A9732-", - "A9733-", - "A9734-", - "T9735-", - "A9736-", - "A9737-", - "A9738-", - "T9739-", - "C9740-", - "C9741-", - "A9742-", - "C9743-", - "A9744-", - "T9745-", - "T9746-", - "T9747-", - "G9748-", - "G9749-", - "C9750-", - "T9751-", - "A9752-", - "A9753-", - "T9754-", - "C9755-", - "G9756-", - "A9757-", - "T9758-", - "T9759-", - "T9760-", - "C9761-", - "G9762-", - "G9763-", - "G9764-", - "C9765-", - "T9766-", - "T9767-", - "G9768-", - "G9769-", - "A9770-", - "A9771-", - "A9772-", - "A9773-", - "A9774-", - "A9775-", - "C9776-", - "G9777-", - "T9778-", - "A9779-", - "T9780-", - "C9781-", - "G9782-", - "C9783-", - "C9784-", - "G9785-", - "G9786-", - "A9787-", - "A9788-", - "G9789-", - "G9790-", - "G9791-", - "A9792-", - "C9793-", - "T9794-", - "A9795-", - "T9796-", - "A9797-", - "T9798-", - "G9799-", - "A9800-", - "C9801-", - "T9802-", - "A9803-", - "A9804-", - "C9805-", - "T9806-", - "T9807-", - "A9808-", - "T9809-", - "C9810-", - "T9811-", - "A9812-", - "G9813-", - "A9814-", - "G9815-", - "A9816-", - "T9817-", - "A9818-", - "C9819-", - "A9820-", - "G9821-", - "G9822-", - "A9823-", - "A9824-", - "T9825-", - "A9826-", - "C9827-", - "A9828-", - "A9829-", - "C9830-", - "A9831-", - "A9832-", - "T9833-", - "C9834-", - "A9835-", - "A9836-", - "A9837-", - "A9838-", - "C9839-", - "T9840-", - "T9841-", - "A9842-", - "C9843-", - "T9844-", - "G9845-", - "A9846-", - "A9847-", - "A9848-", - "C9849-", - "T9850-", - "A9851-", - "T9852-", - "A9853-", - "C9854-", - "G9855-", - "T9856-", - "A9857-", - "A9858-", - "C9859-", - "T9860-", - "G9861-", - "T9862-", - "C9863-", - "A9864-", - "A9865-", - "A9866-", - "A9867-", - "A9868-", - "A9869-", - "A9870-", - "T9871-", - "A9872-", - "A9873-", - "A9874-", - "A9875-", - "A9876-", - "C9877-", - "A9878-", - "T9879-", - "A9880-", - "T9881-", - "A9882-", - "T9883-", - "G9884-", - "G9885-", - "T9886-", - "C9887-", - "T9888-", - "A9889-", - "T9890-", - "A9891-", - "T9892-", - "A9893-", - "T9894-", - "A9895-", - "C9896-", - "A9897-", - "C9898-", - "T9899-", - "A9900-", - "C9901-", - "A9902-", - "A9903-", - "T9904-", - "T9905-", - "T9906-", - "A9907-", - "G9908-", - "T9909-", - "T9910-", - "A9911-", - "T9912-", - "T9913-", - "A9914-", - "A9915-", - "T9916-", - "G9917-", - "T9918-", - "G9919-", - "G9920-", - "T9921-", - "T9922-", - "A9923-", - "T9924-", - "T9925-", - "G9926-", - "A9927-", - "T9928-", - "T9929-", - "G9930-", - "G9931-", - "A9932-", - "T9933-", - "A9934-", - "A9935-", - "C9936-", - "C9937-", - "G9938-", - "A9939-", - "T9940-", - "G9941-", - "T9942-", - "G9943-", - "A9944-", - "T9945-", - "T9946-", - "G9947-", - "T9948-", - "T9949-", - "C9950-", - "A9951-", - "A9952-", - "T9953-", - "C9954-", - "A9955-", - "A9956-", - "T9957-", - "A9958-", - "T9959-", - "T9960-", - "A9961-", - "A9962-", - "G9963-", - "A9964-", - "G9965-", - "G9966-", - "G9967-", - "T9968-", - "T9969-", - "G9970-", - "G9971-", - "T9972-", - "A9973-", - "A9974-", - "A9975-", - "T9976-", - "T9977-", - "G9978-", - "G9979-", - "T9980-", - "A9981-", - "C9982-", - "A9983-", - "T9984-", - "A9985-", - "G9986-", - "C9987-", - "T9988-", - "A9989-", - "A9990-", - "T9991-", - "A9992-", - "A9993-", - "T9994-", - "A9995-", - "C9996-", - "A9997-", - "T9998-", - "A9999-", - "T10000-", - "A10001-", - "C10002-", - "T10003-", - "C10004-", - "C10005-", - "A10006-", - "A10007-", - "A10008-", - "T10009-", - "A10010-", - "C10011-", - "A10012-", - "C10013-", - "C10014-", - "C10015-", - "A10016-", - "A10017-", - "T10018-", - "A10019-", - "A10020-", - "T10021-", - "A10022-", - "C10023-", - "T10024-", - "A10025-", - "C10026-", - "A10027-", - "A10028-", - "C10029-", - "C10030-", - "A10031-", - "T10032-", - "T10033-", - "T10034-", - "C10035-", - "T10036-", - "G10037-", - "A10038-", - "G10039-", - "T10040-", - "T10041-", - "G10042-", - "G10043-", - "A10044-", - "T10045-", - "A10046-", - "T10047-", - "C10048-", - "A10049-", - "T10050-", - "C10051-", - "A10052-", - "A10053-", - "A10054-", - "A10055-", - "T10056-", - "A10057-", - "C10058-", - "T10059-", - "G10060-", - "G10061-", - "A10062-", - "T10063-", - "A10064-", - "A10065-", - "A10066-", - "T10067-", - "A10068-", - "C10069-", - "G10070-", - "A10071-", - "G10072-", - "G10073-", - "A10074-", - "C10075-", - "A10076-", - "T10077-", - "G10078-", - "T10079-", - "A10080-", - "T10081-", - "A10082-", - "G10083-", - "A10084-", - "G10085-", - "T10086-", - "A10087-", - "A10088-", - "G10089-", - "T10090-", - "A10091-", - "A10092-", - "A10093-", - "G10094-", - "A10095-", - "A10096-", - "A10097-", - "A10098-", - "A10099-", - "G10100-", - "A10101-", - "A10102-", - "T10103-", - "G10104-", - "T10105-", - "G10106-", - "G10107-", - "A10108-", - "A10109-", - "T10110-", - "T10111-", - "T10112-", - "G10113-", - "C10114-", - "T10115-", - "A10116-", - "T10117-", - "G10118-", - "A10119-", - "A10120-", - "G10121-", - "T10122-", - "T10123-", - "G10124-", - "T10125-", - "T10126-", - "T10127-", - "A10128-", - "C10129-", - "T10130-", - "C10131-", - "A10132-", - "A10133-", - "A10134-", - "A10135-", - "C10136-", - "G10137-", - "A10138-", - "T10139-", - "T10140-", - "A10141-", - "G10142-", - "A10143-", - "A10144-", - "A10145-", - "A10146-", - "C10147-", - "G10148-", - "A10149-", - "T10150-", - "A10151-", - "G10152-", - "A10153-", - "T10154-", - "A10155-", - "C10156-", - "T10157-", - "T10158-", - "T10159-", - "G10160-", - "G10161-", - "T10162-", - "T10163-", - "T10164-", - "A10165-", - "T10166-", - "T10167-", - "G10168-", - "G10169-", - "A10170-", - "T10171-", - "T10172-", - "C10173-", - "G10174-", - "T10175-", - "G10176-", - "T10177-", - "A10178-", - "A10179-", - "T10180-", - "C10181-", - "A10182-", - "T10183-", - "A10184-", - "T10185-", - "A10186-", - "T10187-", - "T10188-", - "T10189-", - "T10190-", - "G10191-", - "C10192-", - "A10193-", - "T10194-", - "A10195-", - "A10196-", - "C10197-", - "A10198-", - "T10199-", - "G10200-", - "T10201-", - "A10202-", - "T10203-", - "C10204-", - "A10205-", - "A10206-", - "T10207-", - "A10208-", - "T10209-", - "A10210-", - "T10211-", - "G10212-", - "G10213-", - "C10214-", - "A10215-", - "T10216-", - "A10217-", - "G10218-", - "A10219-", - "A10220-", - "C10221-", - "A10222-", - "C10223-", - "G10224-", - "A10225-", - "A10226-", - "G10227-", - "A10228-", - "G10229-", - "A10230-", - "A10231-", - "A10232-", - "C10233-", - "C10234-", - "G10235-", - "G10236-", - "T10237-", - "G10238-", - "C10239-", - "G10240-", - "T10241-", - "C10242-", - "A10243-", - "G10244-", - "A10245-", - "T10246-", - "A10247-", - "A10248-", - "T10249-", - "T10250-", - "G10251-", - "T10252-", - "C10253-", - "C10254-", - "T10255-", - "A10256-", - "T10257-", - "A10258-", - "T10259-", - "G10260-", - "C10261-", - "C10262-", - "G10263-", - "T10264-", - "A10265-", - "C10266-", - "A10267-", - "C10268-", - "G10269-", - "T10270-", - "T10271-", - "T10272-", - "T10273-", - "A10274-", - "A10275-", - "A10276-", - "A10277-", - "A10278-", - "A10279-", - "A10280-", - "T10281-", - "A10282-", - "A10283-", - "C10284-", - "A10285-", - "A10286-", - "T10287-", - "G10288-", - "A10289-", - "G10290-", - "C10291-", - "A10292-", - "A10293-", - "G10294-", - "T10295-", - "T10296-", - "C10297-", - "T10298-", - "A10299-", - "T10300-", - "A10301-", - "A10302-", - "G10303-", - "C10304-", - "T10305-", - "A10306-", - "G10307-", - "T10308-", - "T10309-", - "A10310-", - "A10311-", - "C10312-", - "T10313-", - "A10314-", - "A10315-", - "T10316-", - "A10317-", - "A10318-", - "A10319-", - "T10320-", - "A10321-", - "A10322-", - "A10323-", - "A10324-", - "A10325-", - "G10326-", - "T10327-", - "T10328-", - "T10329-", - "A10330-", - "A10331-", - "T10332-", - "T10333-", - "A10334-", - "T10335-", - "C10336-", - "G10337-", - "A10338-", - "C10339-", - "G10340-", - "A10341-", - "T10342-", - "A10343-", - "T10344-", - "A10345-", - "T10346-", - "G10347-", - "T10348-", - "C10349-", - "G10350-", - "T10351-", - "T10352-", - "A10353-", - "T10354-", - "T10355-", - "T10356-", - "T10357-", - "T10358-", - "C10359-", - "T10360-", - "C10361-", - "T10362-", - "C10363-", - "A10364-", - "T10365-", - "A10366-", - "T10367-", - "G10368-", - "A10369-", - "A10370-", - "A10371-", - "G10372-", - "A10373-", - "T10374-", - "T10375-", - "A10376-", - "A10377-", - "T10378-", - "T10379-", - "T10380-", - "G10381-", - "A10382-", - "T10383-", - "T10384-", - "C10385-", - "T10386-", - "A10387-", - "A10388-", - "T10389-", - "A10390-", - "T10391-", - "A10392-", - "A10393-", - "T10394-", - "C10395-", - "T10396-", - "T10397-", - "C10398-", - "A10399-", - "G10400-", - "T10401-", - "A10402-", - "T10403-", - "T10404-", - "G10405-", - "G10406-", - "A10407-", - "T10408-", - "G10409-", - "A10410-", - "A10411-", - "T10412-", - "C10413-", - "T10414-", - "C10415-", - "A10416-", - "A10417-", - "T10418-", - "T10419-", - "C10420-", - "A10421-", - "A10422-", - "A10423-", - "T10424-", - "T10425-", - "A10426-", - "A10427-", - "T10428-", - "T10429-", - "C10430-", - "C10431-", - "A10432-", - "T10433-", - "T10434-", - "A10435-", - "G10436-", - "A10437-", - "T10438-", - "T10439-", - "A10440-", - "G10441-", - "A10442-", - "T10443-", - "T10444-", - "A10445-", - "G10446-", - "A10447-", - "T10448-", - "T10449-", - "A10450-", - "G10451-", - "A10452-", - "T10453-", - "C10454-", - "A10455-", - "T10456-", - "A10457-", - "A10458-", - "A10459-", - "T10460-", - "A10461-", - "A10462-", - "A10463-", - "A10464-", - "A10465-", - "T10466-", - "A10467-", - "G10468-", - "T10469-", - "A10470-", - "G10471-", - "C10472-", - "A10473-", - "C10474-", - "G10475-", - "C10476-", - "A10477-", - "C10478-", - "T10479-", - "A10480-", - "C10481-", - "T10482-", - "T10483-", - "C10484-", - "A10485-", - "G10486-", - "C10487-", - "C10488-", - "A10489-", - "A10490-", - "A10491-", - "T10492-", - "A10493-", - "T10494-", - "T10495-", - "C10496-", - "T10497-", - "T10498-", - "T10499-", - "T10500-", - "T10501-", - "T10502-", - "G10503-", - "A10504-", - "A10505-", - "A10506-", - "C10507-", - "G10508-", - "C10509-", - "C10510-", - "A10511-", - "T10512-", - "C10513-", - "T10514-", - "A10515-", - "G10516-", - "C10517-", - "G10518-", - "T10519-", - "A10520-", - "A10521-", - "T10522-", - "G10523-", - "A10524-", - "G10525-", - "A10526-", - "A10527-", - "C10528-", - "A10529-", - "C10530-", - "A10531-", - "A10532-", - "G10533-", - "T10534-", - "G10535-", - "A10536-", - "A10537-", - "C10538-", - "C10539-", - "T10540-", - "A10541-", - "T10542-", - "A10543-", - "A10544-", - "T10545-", - "G10546-", - "A10547-", - "G10548-", - "C10549-", - "A10550-", - "A10551-", - "A10552-", - "T10553-", - "T10554-", - "T10555-", - "A10556-", - "T10557-", - "T10558-", - "A10559-", - "G10560-", - "T10561-", - "A10562-", - "T10563-", - "C10564-", - "G10565-", - "G10566-", - "T10567-", - "T10568-", - "A10569-", - "C10570-", - "A10571-", - "T10572-", - "G10573-", - "A10574-", - "A10575-", - "G10576-", - "G10577-", - "A10578-", - "C10579-", - "T10580-", - "T10581-", - "T10582-", - "A10583-", - "C10584-", - "G10585-", - "T10586-", - "A10587-", - "G10588-", - "A10589-", - "G10590-", - "T10591-", - "G10592-", - "G10593-", - "T10594-", - "G10595-", - "A10596-", - "T10597-", - "T10598-", - "C10599-", - "C10600-", - "T10601-", - "C10602-", - "C10603-", - "A10604-", - "T10605-", - "C10606-", - "T10607-", - "G10608-", - "T10609-", - "G10610-", - "G10611-", - "T10612-", - "A10613-", - "C10614-", - "G10615-", - "A10616-", - "A10617-", - "C10618-", - "G10619-", - "G10620-", - "T10621-", - "T10622-", - "T10623-", - "C10624-", - "A10625-", - "T10626-", - "C10627-", - "T10628-", - "T10629-", - "C10630-", - "T10631-", - "T10632-", - "T10633-", - "G10634-", - "A10635-", - "T10636-", - "G10637-", - "C10638-", - "C10639-", - "A10640-", - "C10641-", - "C10642-", - "A10643-", - "C10644-", - "C10645-", - "C10646-", - "A10647-", - "G10648-", - "A10649-", - "T10650-", - "G10651-", - "T10652-", - "T10653-", - "C10654-", - "T10655-", - "A10656-", - "T10657-", - "A10658-", - "A10659-", - "A10660-", - "C10661-", - "T10662-", - "T10663-", - "G10664-", - "G10665-", - "T10666-", - "A10667-", - "T10668-", - "C10669-", - "C10670-", - "T10671-", - "C10672-", - "G10673-", - "T10674-", - "C10675-", - "C10676-", - "G10677-", - "A10678-", - "T10679-", - "T10680-", - "T10681-", - "C10682-", - "A10683-", - "T10684-", - "A10685-", - "T10686-", - "C10687-", - "A10688-", - "T10689-", - "T10690-", - "T10691-", - "G10692-", - "C10693-", - "C10694-", - "A10695-", - "A10696-", - "C10697-", - "C10698-", - "A10699-", - "A10700-", - "T10701-", - "A10702-", - "C10703-", - "A10704-", - "T10705-", - "A10706-", - "T10707-", - "A10708-", - "G10709-", - "C10710-", - "T10711-", - "A10712-", - "A10713-", - "A10714-", - "C10715-", - "C10716-", - "C10717-", - "A10718-", - "G10719-", - "G10720-", - "C10721-", - "A10722-", - "T10723-", - "A10724-", - "C10725-", - "G10726-", - "T10727-", - "T10728-", - "C10729-", - "C10730-", - "A10731-", - "C10732-", - "A10733-", - "C10734-", - "A10735-", - "T10736-", - "C10737-", - "C10738-", - "G10739-", - "G10740-", - "A10741-", - "A10742-", - "C10743-", - "A10744-", - "A10745-", - "T10746-", - "G10747-", - "A10748-", - "A10749-", - "A10750-", - "T10751-", - "T10752-", - "C10753-", - "T10754-", - "C10755-", - "C10756-", - "A10757-", - "G10758-", - "A10759-", - "A10760-", - "G10761-", - "A10762-", - "T10763-", - "G10764-", - "T10765-", - "T10766-", - "A10767-", - "C10768-", - "A10769-", - "A10770-", - "T10771-", - "G10772-", - "G10773-", - "C10774-", - "T10775-", - "A10776-", - "G10777-", - "A10778-", - "T10779-", - "T10780-", - "T10781-", - "G10782-", - "G10783-", - "A10784-", - "C10785-", - "A10786-", - "T10787-", - "T10788-", - "T10789-", - "G10790-", - "G10791-", - "T10792-", - "T10793-", - "T10794-", - "C10795-", - "A10796-", - "A10797-", - "C10798-", - "C10799-", - "G10800-", - "C10801-", - "G10802-", - "T10803-", - "T10804-", - "A10805-", - "A10806-", - "C10807-", - "A10808-", - "T10809-", - "A10810-", - "T10811-", - "G10812-", - "A10813-", - "G10814-", - "T10815-", - "G10816-", - "A10817-", - "A10818-", - "C10819-", - "A10820-", - "C10821-", - "A10822-", - "C10823-", - "C10824-", - "C10825-", - "A10826-", - "T10827-", - "A10828-", - "C10829-", - "A10830-", - "T10831-", - "G10832-", - "A10833-", - "A10834-", - "A10835-", - "G10836-", - "C10837-", - "G10838-", - "A10839-", - "T10840-", - "G10841-", - "A10842-", - "G10843-", - "A10844-", - "A10845-", - "A10846-", - "T10847-", - "A10848-", - "G10849-", - "G10850-", - "A10851-", - "T10852-", - "T10853-", - "C10854-", - "T10855-", - "C10856-", - "A10857-", - "T10858-", - "C10859-", - "T10860-", - "T10861-", - "G10862-", - "C10863-", - "C10864-", - "A10865-", - "A10866-", - "A10867-", - "A10868-", - "T10869-", - "A10870-", - "T10871-", - "C10872-", - "A10873-", - "C10874-", - "T10875-", - "A10876-", - "T10877-", - "A10878-", - "A10879-", - "A10880-", - "A10881-", - "A10882-", - "A10883-", - "T10884-", - "T10885-", - "T10886-", - "A10887-", - "T10888-", - "T10889-", - "T10890-", - "A10891-", - "T10892-", - "C10893-", - "A10894-", - "A10895-", - "T10896-", - "T10897-", - "T10898-", - "T10899-", - "A10900-", - "A10901-", - "A10902-", - "G10903-", - "G10904-", - "T10905-", - "A10906-", - "T10907-", - "A10908-", - "A10909-", - "A10910-", - "A10911-", - "A10912-", - "A10913-", - "A10914-", - "T10915-", - "A10916-", - "C10917-", - "T10918-", - "T10919-", - "A10920-", - "T10921-", - "T10922-", - "G10923-", - "T10924-", - "T10925-", - "G10926-", - "C10927-", - "T10928-", - "C10929-", - "G10930-", - "A10931-", - "A10932-", - "T10933-", - "A10934-", - "T10935-", - "T10936-", - "T10937-", - "T10938-", - "G10939-", - "T10940-", - "A10941-", - "T10942-", - "T10943-", - "T10944-", - "G10945-", - "A10946-", - "T10947-", - "G10948-", - "G10949-", - "T10950-", - "A10951-", - "T10952-", - "A10953-", - "C10954-", - "G10955-", - "G10956-", - "A10957-", - "A10958-", - "G10959-", - "A10960-", - "T10961-", - "T10962-", - "A10963-", - "G10964-", - "A10965-", - "A10966-", - "A10967-", - "T10968-", - "G10969-", - "T10970-", - "A10971-", - "G10972-", - "G10973-", - "T10974-", - "A10975-", - "T10976-", - "T10977-", - "A10978-", - "T10979-", - "C10980-", - "A10981-", - "T10982-", - "C10983-", - "A10984-", - "A10985-", - "C10986-", - "T10987-", - "G10988-", - "A10989-", - "T10990-", - "T10991-", - "T10992-", - "T10993-", - "A10994-", - "T10995-", - "G10996-", - "A10997-", - "T10998-", - "G10999-", - "G11000-", - "T11001-", - "T11002-", - "T11003-", - "T11004-", - "A11005-", - "T11006-", - "G11007-", - "A11008-", - "A11009-", - "T11010-", - "T11011-", - "T11012-", - "T11013-", - "A11014-", - "T11015-", - "T11016-", - "A11017-", - "T11018-", - "G11019-", - "C11020-", - "T11021-", - "T11022-", - "C11023-", - "A11024-", - "C11025-", - "T11026-", - "A11027-", - "T11028-", - "T11029-", - "G11030-", - "C11031-", - "A11032-", - "T11033-", - "C11034-", - "G11035-", - "G11036-", - "A11037-", - "A11038-", - "A11039-", - "T11040-", - "A11041-", - "A11042-", - "T11043-", - "A11044-", - "T11045-", - "C11046-", - "A11047-", - "T11048-", - "A11049-", - "T11050-", - "G11051-", - "C11052-", - "T11053-", - "T11054-", - "C11055-", - "C11056-", - "A11057-", - "C11058-", - "G11059-", - "T11060-", - "A11061-", - "T11062-", - "A11063-", - "T11064-", - "T11065-", - "T11066-", - "T11067-", - "A11068-", - "T11069-", - "T11070-", - "T11071-", - "T11072-", - "G11073-", - "T11074-", - "T11075-", - "T11076-", - "T11077-", - "G11078-", - "A11079-", - "C11080-", - "T11081-", - "C11082-", - "A11083-", - "T11084-", - "A11085-", - "A11086-", - "T11087-", - "A11088-", - "C11089-", - "G11090-", - "C11091-", - "A11092-", - "C11093-", - "G11094-", - "T11095-", - "A11096-", - "A11097-", - "T11098-", - "T11099-", - "C11100-", - "T11101-", - "G11102-", - "G11103-", - "A11104-", - "T11105-", - "T11106-", - "A11107-", - "T11108-", - "T11109-", - "G11110-", - "G11111-", - "C11112-", - "A11113-", - "T11114-", - "A11115-", - "T11116-", - "C11117-", - "G11118-", - "A11119-", - "T11120-", - "G11121-", - "A11122-", - "A11123-", - "T11124-", - "A11125-", - "A11126-", - "T11127-", - "T11128-", - "T11129-", - "T11130-", - "A11131-", - "G11132-", - "C11133-", - "T11134-", - "C11135-", - "C11136-", - "A11137-", - "T11138-", - "G11139-", - "C11140-", - "T11141-", - "C11142-", - "A11143-", - "G11144-", - "T11145-", - "A11146-", - "A11147-", - "A11148-", - "T11149-", - "A11150-", - "T11151-", - "T11152-", - "A11153-", - "A11154-", - "T11155-", - "G11156-", - "A11157-", - "G11158-", - "A11159-", - "A11160-", - "C11161-", - "A11162-", - "T11163-", - "A11164-", - "G11165-", - "T11166-", - "G11167-", - "T11168-", - "T11169-", - "G11170-", - "C11171-", - "C11172-", - "T11173-", - "C11174-", - "C11175-", - "T11176-", - "A11177-", - "C11178-", - "C11179-", - "A11180-", - "T11181-", - "T11182-", - "A11183-", - "T11184-", - "T11185-", - "T11186-", - "T11187-", - "T11188-", - "T11189-", - "T11190-", - "C11191-", - "A11192-", - "T11193-", - "C11194-", - "T11195-", - "C11196-", - "A11197-", - "T11198-", - "T11199-", - "C11200-", - "A11201-", - "A11202-", - "T11203-", - "T11204-", - "C11205-", - "T11206-", - "T11207-", - "G11208-", - "A11209-", - "T11210-", - "T11211-", - "G11212-", - "C11213-", - "A11214-", - "G11215-", - "A11216-", - "G11217-", - "A11218-", - "T11219-", - "C11220-", - "T11221-", - "A11222-", - "T11223-", - "A11224-", - "T11225-", - "A11226-", - "A11227-", - "T11228-", - "C11229-", - "A11230-", - "T11231-", - "T11232-", - "A11233-", - "T11234-", - "A11235-", - "G11236-", - "C11237-", - "G11238-", - "T11239-", - "T11240-", - "G11241-", - "A11242-", - "C11243-", - "T11244-", - "T11245-", - "A11246-", - "T11247-", - "G11248-", - "G11249-", - "A11250-", - "C11251-", - "T11252-", - "C11253-", - "T11254-", - "G11255-", - "G11256-", - "A11257-", - "A11258-", - "T11259-", - "C11260-", - "T11261-", - "T11262-", - "A11263-", - "G11264-", - "A11265-", - "C11266-", - "G11267-", - "A11268-", - "T11269-", - "G11270-", - "T11271-", - "A11272-", - "C11273-", - "A11274-", - "G11275-", - "T11276-", - "C11277-", - "A11278-", - "T11279-", - "C11280-", - "T11281-", - "A11282-", - "T11283-", - "A11284-", - "A11285-", - "T11286-", - "C11287-", - "A11288-", - "T11289-", - "G11290-", - "G11291-", - "T11292-", - "A11293-", - "T11294-", - "A11295-", - "T11296-", - "T11297-", - "T11298-", - "A11299-", - "A11300-", - "T11301-", - "A11302-", - "C11303-", - "A11304-", - "T11305-", - "T11306-", - "G11307-", - "T11308-", - "T11309-", - "T11310-", - "T11311-", - "A11312-", - "T11313-", - "A11314-", - "G11315-", - "C11316-", - "A11317-", - "T11318-", - "A11319-", - "G11320-", - "G11321-", - "C11322-", - "A11323-", - "T11324-", - "T11325-", - "A11326-", - "T11327-", - "C11328-", - "T11329-", - "A11330-", - "C11331-", - "G11332-", - "A11333-", - "T11334-", - "A11335-", - "T11336-", - "T11337-", - "A11338-", - "G11339-", - "A11340-", - "T11341-", - "A11342-", - "C11343-", - "T11344-", - "T11345-", - "C11346-", - "A11347-", - "C11348-", - "T11349-", - "C11350-", - "A11351-", - "A11352-", - "T11353-", - "G11354-", - "A11355-", - "A11356-", - "T11357-", - "C11358-", - "A11359-", - "A11360-", - "T11361-", - "C11362-", - "A11363-", - "C11364-", - "A11365-", - "C11366-", - "A11367-", - "A11368-", - "T11369-", - "C11370-", - "T11371-", - "A11372-", - "A11373-", - "T11374-", - "G11375-", - "T11376-", - "A11377-", - "G11378-", - "G11379-", - "T11380-", - "T11381-", - "T11382-", - "A11383-", - "T11384-", - "G11385-", - "A11386-", - "C11387-", - "A11388-", - "T11389-", - "A11390-", - "A11391-", - "T11392-", - "A11393-", - "G11394-", - "C11395-", - "A11396-", - "T11397-", - "T11398-", - "T11399-", - "T11400-", - "C11401-", - "A11402-", - "G11403-", - "C11404-", - "A11405-", - "G11406-", - "T11407-", - "T11408-", - "C11409-", - "A11410-", - "A11411-", - "T11412-", - "G11413-", - "T11414-", - "T11415-", - "T11416-", - "C11417-", - "T11418-", - "A11419-", - "G11420-", - "A11421-", - "T11422-", - "T11423-", - "C11424-", - "G11425-", - "T11426-", - "T11427-", - "G11428-", - "A11429-", - "T11430-", - "G11431-", - "G11432-", - "C11433-", - "A11434-", - "A11435-", - "T11436-", - "G11437-", - "G11438-", - "T11439-", - "T11440-", - "A11441-", - "T11442-", - "A11443-", - "C11444-", - "A11445-", - "T11446-", - "G11447-", - "T11448-", - "A11449-", - "T11450-", - "A11451-", - "T11452-", - "C11453-", - "C11454-", - "G11455-", - "T11456-", - "T11457-", - "A11458-", - "T11459-", - "T11460-", - "T11461-", - "G11462-", - "A11463-", - "T11464-", - "C11465-", - "T11466-", - "A11467-", - "A11468-", - "T11469-", - "G11470-", - "T11471-", - "T11472-", - "G11473-", - "A11474-", - "C11475-", - "A11476-", - "T11477-", - "C11478-", - "T11479-", - "G11480-", - "A11481-", - "A11482-", - "C11483-", - "C11484-", - "G11485-", - "G11486-", - "A11487-", - "T11488-", - "T11489-", - "C11490-", - "T11491-", - "A11492-", - "G11493-", - "C11494-", - "A11495-", - "G11496-", - "T11497-", - "A11498-", - "A11499-", - "A11500-", - "G11501-", - "A11502-", - "T11503-", - "A11504-", - "C11505-", - "T11506-", - "A11507-", - "G11508-", - "A11509-", - "G11510-", - "A11511-", - "T11512-", - "T11513-", - "G11514-", - "T11515-", - "T11516-", - "T11517-", - "A11518-", - "T11519-", - "T11520-", - "A11521-", - "T11522-", - "A11523-", - "T11524-", - "C11525-", - "T11526-", - "A11527-", - "A11528-", - "C11529-", - "A11530-", - "G11531-", - "C11532-", - "C11533-", - "T11534-", - "T11535-", - "G11536-", - "T11537-", - "G11538-", - "A11539-", - "A11540-", - "G11541-", - "A11542-", - "A11543-", - "G11544-", - "T11545-", - "G11546-", - "T11547-", - "T11548-", - "T11549-", - "C11550-", - "T11551-", - "C11552-", - "C11553-", - "T11554-", - "C11555-", - "G11556-", - "T11557-", - "T11558-", - "T11559-", - "G11560-", - "T11561-", - "C11562-", - "A11563-", - "A11564-", - "T11565-", - "C11566-", - "A11567-", - "T11568-", - "G11569-", - "T11570-", - "T11571-", - "A11572-", - "A11573-", - "T11574-", - "G11575-", - "T11576-", - "C11577-", - "T11578-", - "T11579-", - "T11580-", - "A11581-", - "A11582-", - "G11583-", - "A11584-", - "T11585-", - "A11586-", - "A11587-", - "G11588-", - "G11589-", - "T11590-", - "A11591-", - "G11592-", - "A11593-", - "C11594-", - "A11595-", - "A11596-", - "A11597-", - "T11598-", - "G11599-", - "T11600-", - "T11601-", - "T11602-", - "A11603-", - "T11604-", - "A11605-", - "G11606-", - "T11607-", - "A11608-", - "C11609-", - "T11610-", - "A11611-", - "A11612-", - "G11613-", - "A11614-", - "A11615-", - "T11616-", - "T11617-", - "G11618-", - "G11619-", - "G11620-", - "C11621-", - "A11622-", - "A11623-", - "A11624-", - "C11625-", - "A11626-", - "T11627-", - "A11628-", - "A11629-", - "G11630-", - "A11631-", - "C11632-", - "A11633-", - "T11634-", - "G11635-", - "T11636-", - "C11637-", - "A11638-", - "C11639-", - "A11640-", - "A11641-", - "A11642-", - "G11643-", - "A11644-", - "C11645-", - "C11646-", - "C11647-", - "T11648-", - "T11649-", - "T11650-", - "T11651-", - "T11652-", - "G11653-", - "T11654-", - "A11655-", - "T11656-", - "G11657-", - "T11658-", - "A11659-", - "T11660-", - "A11661-", - "A11662-", - "G11663-", - "T11664-", - "G11665-", - "T11666-", - "A11667-", - "G11668-", - "A11669-", - "A11670-", - "A11671-", - "T11672-", - "T11673-", - "A11674-", - "T11675-", - "A11676-", - "A11677-", - "C11678-", - "A11679-", - "T11680-", - "C11681-", - "C11682-", - "A11683-", - "T11684-", - "A11685-", - "G11686-", - "T11687-", - "T11688-", - "G11689-", - "G11690-", - "A11691-", - "T11692-", - "T11693-", - "C11694-", - "A11695-", - "C11696-", - "A11697-", - "T11698-", - "A11699-", - "G11700-", - "G11701-", - "T11702-", - "G11703-", - "T11704-", - "C11705-", - "C11706-", - "A11707-", - "A11708-", - "T11709-", - "C11710-", - "G11711-", - "G11712-", - "G11713-", - "A11714-", - "T11715-", - "C11716-", - "T11717-", - "C11718-", - "T11719-", - "C11720-", - "C11721-", - "C11727T", - "C39139T", - "-173274A", - "-173275T", - "-173276A", - "-173277T", - "A185257-", - "T185258-", - "A185259-", - "G185260-", - "A185261-", - "A185262-", - "T185263-", - "G185264-", - "T185265-", - "T185266-", - "T185267-", - "G185268-", - "C185269-", - "C185270-", - "A185271-", - "C185272-", - "A185273-", - "T185274-", - "T185275-", - "G185276-", - "G185277-", - "C185278-", - "T185279-", - "A185280-", - "G185281-", - "A185282-", - "G185283-", - "G185284-", - "A185285-", - "A185286-", - "T185287-", - "G185288-", - "C185289-", - "C185290-", - "G185291-", - "T185292-", - "T185293-", - "T185294-", - "A185295-", - "G185296-", - "A185297-", - "T185298-", - "C185299-", - "A185300-", - "A185301-", - "C185302-", - "G185303-", - "T185304-", - "A185305-", - "T185306-", - "T185307-", - "G185308-", - "C185309-", - "G185310-", - "A185311-", - "T185312-", - "A185313-", - "A185314-", - "C185315-", - "A185316-", - "G185317-", - "A185318-", - "C185319-", - "G185320-", - "A185321-", - "C185322-", - "G185323-", - "A185324-", - "T185325-", - "C185326-", - "A185327-", - "G185328-", - "G185329-", - "T185330-", - "T185331-", - "G185332-", - "T185333-", - "T185334-", - "A185335-", - "T185336-", - "T185337-", - "A185338-", - "T185339-", - "G185340-", - "C185341-", - "A185342-", - "G185343-", - "G185344-", - "A185345-", - "A185346-", - "T185347-", - "A185348-", - "C185349-", - "C185350-", - "A185351-", - "T185352-", - "T185353-", - "T185354-", - "C185355-", - "A185356-", - "T185357-", - "G185358-", - "A185359-", - "A185360-", - "G185361-", - "A185362-", - "T185363-", - "A185364-", - "G185365-", - "T185366-", - "G185367-", - "T185368-", - "A185369-", - "G185370-", - "A185371-", - "A185372-", - "A185373-", - "C185374-", - "A185375-", - "G185376-", - "A185377-", - "T185378-", - "A185379-", - "T185380-", - "A185381-", - "C185382-", - "A185383-", - "T185384-", - "T185385-", - "A185386-", - "T185387-", - "G185388-", - "G185389-", - "A185390-", - "C185391-", - "C185392-", - "A185393-", - "G185394-", - "A185395-", - "A185396-", - "A185397-", - "T185398-", - "A185399-", - "A185400-", - "T185401-", - "G185402-", - "T185403-", - "T185404-", - "A185405-", - "A185406-", - "A185407-", - "G185408-", - "G185409-", - "A185410-", - "A185411-", - "A185412-", - "C185413-", - "A185414-", - "T185415-", - "A185416-", - "T185417-", - "G185418-", - "A185419-", - "C185420-", - "A185421-", - "T185422-", - "A185423-", - "A185424-", - "A185425-", - "C185426-", - "A185427-", - "G185428-", - "T185429-", - "A185430-", - "T185431-", - "T185432-", - "G185433-", - "A185434-", - "C185435-", - "C185436-", - "C185437-", - "A185438-", - "C185439-", - "G185440-", - "A185441-", - "G185442-", - "T185443-", - "T185444-", - "A185445-", - "T185446-", - "A185447-", - "A185448-", - "C185449-", - "A185450-", - "A185451-", - "A185452-", - "G185453-", - "T185454-", - "C185455-", - "A185456-", - "A185457-", - "A185458-", - "G185459-", - "A185460-", - "C185461-", - "C185462-", - "C185463-", - "A185464-", - "T185465-", - "T185466-", - "T185467-", - "T185468-", - "C185469-", - "C185470-", - "T185471-", - "G185472-", - "C185473-", - "T185474-", - "C185475-", - "C185476-", - "A185477-", - "T185478-", - "T185479-", - "G185480-", - "A185481-", - "G185482-", - "T185483-", - "G185484-", - "T185485-", - "A185486-", - "A185487-", - "A185488-", - "A185489-", - "T185490-", - "T185491-", - "C185492-", - "A185493-", - "T185494-", - "G185495-", - "G185496-", - "T185497-", - "T185498-", - "G185499-", - "A185500-", - "C185501-", - "A185502-", - "A185503-", - "T185504-", - "T185505-", - "T185506-", - "A185507-", - "G185508-", - "G185509-", - "A185510-", - "A185511-", - "A185512-", - "T185513-", - "G185514-", - "G185515-", - "A185516-", - "T185517-", - "A185518-", - "T185519-", - "G185520-", - "A185521-", - "C185522-", - "A185523-", - "A185524-", - "C185525-", - "C185526-", - "C185527-", - "T185528-", - "A185529-", - "A185530-", - "T185531-", - "T185532-", - "C185533-", - "A185534-", - "T185535-", - "T185536-", - "T185537-", - "T185538-", - "G185539-", - "G185540-", - "G185541-", - "A185542-", - "A185543-", - "G185544-", - "A185545-", - "T185546-", - "G185547-", - "C185548-", - "T185549-", - "A185550-", - "A185551-", - "A185552-", - "A185553-", - "C185554-", - "T185555-", - "A185556-", - "A185557-", - "G185558-", - "A185559-", - "A185560-", - "A185561-", - "C185562-", - "G185563-", - "G185564-", - "A185565-", - "C185566-", - "A185567-", - "T185568-", - "A185569-", - "T185570-", - "A185571-", - "G185572-", - "T185573-", - "G185574-", - "C185575-", - "A185576-", - "A185577-", - "T185578-", - "G185579-", - "A185580-", - "C185581-", - "G185582-", - "A185583-", - "T185584-", - "A185585-", - "A185586-", - "A185587-", - "A185588-", - "G185589-", - "T185590-", - "C185591-", - "C185592-", - "T185593-", - "A185594-", - "C185595-", - "C185596-", - "A185597-", - "T185598-", - "G185599-", - "T185600-", - "A185601-", - "C185602-", - "A185603-", - "G185604-", - "T185605-", - "G185606-", - "A185607-", - "G185608-", - "A185609-", - "A185610-", - "A185611-", - "T185612-", - "A185613-", - "A185614-", - "A185615-", - "A185616-", - "A185617-", - "T185618-", - "A185619-", - "T185620-", - "A185621-", - "G185622-", - "A185623-", - "C185624-", - "T185625-", - "T185626-", - "T185627-", - "G185628-", - "G185629-", - "A185630-", - "T185631-", - "A185632-", - "T185633-", - "A185634-", - "A185635-", - "C185636-", - "T185637-", - "A185638-", - "T185639-", - "G185640-", - "G185641-", - "A185642-", - "G185643-", - "A185644-", - "T185645-", - "A185646-", - "T185647-", - "T185648-", - "A185649-", - "T185650-", - "T185651-", - "T185652-", - "C185653-", - "T185654-", - "A185655-", - "A185656-", - "T185657-", - "A185658-", - "T185659-", - "G185660-", - "G185661-", - "T185662-", - "T185663-", - "T185664-", - "A185665-", - "T185666-", - "C185667-", - "T185668-", - "A185669-", - "C185670-", - "A185671-", - "A185672-", - "T185673-", - "C185674-", - "T185675-", - "A185676-", - "C185677-", - "T185678-", - "A185679-", - "G185680-", - "T185681-", - "C185682-", - "A185683-", - "G185684-", - "G185685-", - "A185686-", - "T185687-", - "T185688-", - "A185689-", - "T185690-", - "G185691-", - "G185692-", - "A185693-", - "G185694-", - "A185695-", - "T185696-", - "G185697-", - "G185698-", - "T185699-", - "A185700-", - "C185701-", - "C185702-", - "A185703-", - "A185704-", - "A185705-", - "T185706-", - "A185707-", - "T185708-", - "A185709-", - "C185710-", - "A185711-", - "T185712-", - "T185713-", - "T185714-", - "A185715-", - "A185716-", - "A185717-", - "T185718-", - "C185719-", - "C185720-", - "G185721-", - "T185722-", - "A185723-", - "A185724-", - "C185725-", - "T185726-", - "A185727-", - "G185728-", - "A185729-", - "T185730-", - "C185731-", - "A185732-", - "G185733-", - "A185734-", - "T185735-", - "C185736-", - "A185737-", - "T185738-", - "G185739-", - "A185740-", - "G185741-", - "T185742-", - "G185743-", - "T185744-", - "G185745-", - "A185746-", - "A185747-", - "T185748-", - "C185749-", - "T185750-", - "A185751-", - "G185752-", - "C185753-", - "T185754-", - "T185755-", - "A185756-", - "G185757-", - "A185758-", - "T185759-", - "C185760-", - "T185761-", - "A185762-", - "A185763-", - "C185764-", - "G185765-", - "T185766-", - "C185767-", - "T185768-", - "A185769-", - "A185770-", - "G185771-", - "G185772-", - "A185773-", - "A185774-", - "G185775-", - "T185776-", - "A185777-", - "A185778-", - "C185779-", - "T185780-", - "G185781-", - "T185782-", - "G185783-", - "A185784-", - "C185785-", - "A185786-", - "T185787-", - "G185788-", - "T185789-", - "C185790-", - "C185791-", - "T185792-", - "G185793-", - "C185794-", - "G185795-", - "T185796-", - "T185797-", - "T185798-", - "A185799-", - "G185800-", - "T185801-", - "A185802-", - "T185803-", - "A185804-", - "C185805-", - "C185806-", - "A185807-", - "A185808-", - "G185809-", - "A185810-", - "A185811-", - "A185812-", - "T185813-", - "A185814-", - "T185815-", - "A185816-", - "T185817-", - "C185818-", - "A185819-", - "A185820-", - "C185821-", - "A185822-", - "T185823-", - "A185824-", - "T185825-", - "G185826-", - "A185827-", - "A185828-", - "G185829-", - "G185830-", - "T185831-", - "C185832-", - "T185833-", - "A185834-", - "T185835-", - "G185836-", - "C185837-", - "T185838-", - "T185839-", - "T185840-", - "A185841-", - "G185842-", - "T185843-", - "G185844-", - "T185845-", - "T185846-", - "A185847-", - "C185848-", - "T185849-", - "A185850-", - "C185851-", - "A185852-", - "T185853-", - "C185854-", - "T185855-", - "A185856-", - "A185857-", - "A185858-", - "G185859-", - "A185860-", - "T185861-", - "C185862-", - "A185863-", - "T185864-", - "T185865-", - "G185866-", - "T185867-", - "G185868-", - "C185869-", - "T185870-", - "A185871-", - "C185872-", - "A185873-", - "G185874-", - "G185875-", - "T185876-", - "A185877-", - "T185878-", - "T185879-", - "G185880-", - "G185881-", - "T185882-", - "T185883-", - "G185884-", - "G185885-", - "T185886-", - "T185887-", - "A185888-", - "A185889-", - "A185890-", - "A185891-", - "T185892-", - "C185893-", - "T185894-", - "A185895-", - "G185896-", - "T185897-", - "G185898-", - "G185899-", - "T185900-", - "T185901-", - "A185902-", - "T185903-", - "G185904-", - "G185905-", - "G185906-", - "A185907-", - "A185908-", - "G185909-", - "G185910-", - "A185911-", - "A185912-", - "G185913-", - "A185914-", - "T185915-", - "G185916-", - "C185917-", - "T185918-", - "G185919-", - "A185920-", - "T185921-", - "A185922-", - "A185923-", - "A185924-", - "C185925-", - "C185926-", - "A185927-", - "C185928-", - "G185929-", - "T185930-", - "G185931-", - "C185932-", - "T185933-", - "T185934-", - "G185935-", - "T185936-", - "T185937-", - "T185938-", - "T185939-", - "C185940-", - "A185941-", - "T185942-", - "C185943-", - "A185944-", - "T185945-", - "T185946-", - "G185947-", - "G185948-", - "A185949-", - "A185950-", - "T185951-", - "T185952-", - "A185953-", - "T185954-", - "T185955-", - "A185956-", - "C185957-", - "A185958-", - "C185959-", - "A185960-", - "C185961-", - "T185962-", - "G185963-", - "T185964-", - "C185965-", - "G185966-", - "T185967-", - "T185968-", - "G185969-", - "G185970-", - "A185971-", - "T185972-", - "T185973-", - "A185974-", - "T185975-", - "T185976-", - "A185977-", - "C185978-", - "T185979-", - "G185980-", - "T185981-", - "T185982-", - "C185983-", - "A185984-", - "T185985-", - "A185986-", - "C185987-", - "G185988-", - "A185989-", - "A185990-", - "G185991-", - "A185992-", - "T185993-", - "A185994-", - "T185995-", - "T185996-", - "T185997-", - "G185998-", - "G185999-", - "A186000-", - "G186001-", - "A186002-", - "A186003-", - "G186004-", - "C186005-", - "A186006-", - "C186007-", - "C186008-", - "T186009-", - "G186010-", - "G186011-", - "C186012-", - "C186013-", - "T186014-", - "G186015-", - "A186016-", - "C186017-", - "T186018-", - "A186019-", - "T186020-", - "G186021-", - "A186022-", - "T186023-", - "C186024-", - "C186025-", - "A186026-", - "T186027-", - "G186028-", - "T186029-", - "A186030-", - "A186031-", - "G186032-", - "T186033-", - "C186034-", - "A186035-", - "T186036-", - "A186037-", - "T186038-", - "A186039-", - "T186040-", - "C186041-", - "C186042-", - "A186043-", - "T186044-", - "A186045-", - "T186046-", - "A186047-", - "G186048-", - "A186049-", - "G186050-", - "T186051-", - "A186052-", - "T186053-", - "A186054-", - "G186055-", - "A186056-", - "G186057-", - "A186058-", - "T186059-", - "A186060-", - "C186061-", - "A186062-", - "T186063-", - "G186064-", - "G186065-", - "A186066-", - "T186067-", - "A186068-", - "G186069-", - "A186070-", - "A186071-", - "T186072-", - "C186073-", - "T186074-", - "A186075-", - "A186076-", - "T186077-", - "G186078-", - "T186079-", - "G186080-", - "T186081-", - "T186082-", - "A186083-", - "C186084-", - "A186085-", - "G186086-", - "C186087-", - "A186088-", - "A186089-", - "C186090-", - "C186091-", - "T186092-", - "C186093-", - "C186094-", - "T186095-", - "T186096-", - "A186097-", - "C186098-", - "A186099-", - "C186100-", - "A186101-", - "T186102-", - "T186103-", - "C186104-", - "G186105-", - "A186106-", - "A186107-", - "T186108-", - "T186109-", - "C186110-", - "A186111-", - "T186112-", - "T186113-", - "C186114-", - "A186115-", - "T186116-", - "G186117-", - "A186118-", - "C186119-", - "A186120-", - "A186121-", - "T186122-", - "T186123-", - "C186124-", - "T186125-", - "A186126-", - "A186127-", - "C186128-", - "G186129-", - "A186130-", - "A186131-", - "T186132-", - "A186133-", - "T186134-", - "G186135-", - "T186136-", - "G186137-", - "G186138-", - "A186139-", - "T186140-", - "A186141-", - "A186142-", - "A186143-", - "G186144-", - "A186145-", - "A186146-", - "A186147-", - "T186148-", - "T186149-", - "A186150-", - "G186151-", - "T186152-", - "A186153-", - "A186154-", - "C186155-", - "A186156-", - "A186157-", - "A186158-", - "T186159-", - "T186160-", - "A186161-", - "A186162-", - "A186163-", - "T186164-", - "G186165-", - "A186166-", - "T186167-", - "C186168-", - "T186169-", - "G186170-", - "T186171-", - "A186172-", - "C186173-", - "A186174-", - "A186175-", - "T186176-", - "G186177-", - "A186178-", - "A186179-", - "T186180-", - "A186181-", - "C186182-", - "A186183-", - "A186184-", - "G186185-", - "A186186-", - "A186187-", - "G186188-", - "A186189-", - "T186190-", - "T186191-", - "A186192-", - "T186193-", - "G186194-", - "G186195-", - "A186196-", - "A186197-", - "T186198-", - "A186199-", - "T186200-", - "A186201-", - "G186202-", - "C186203-", - "G186204-", - "A186205-", - "C186206-", - "G186207-", - "G186208-", - "A186209-", - "T186210-", - "C186211-", - "A186212-", - "T186213-", - "T186214-", - "G186215-", - "C186216-", - "C186217-", - "G186218-", - "G186219-", - "C186220-", - "G186221-", - "T186222-", - "C186223-", - "T186224-", - "A186225-", - "T186226-", - "A186227-", - "A186228-", - "A186229-", - "C186230-", - "A186231-", - "G186232-", - "A186233-", - "T186234-", - "T186235-", - "A186236-", - "G186237-", - "C186238-", - "A186239-", - "A186240-", - "A186241-", - "G186242-", - "G186243-", - "C186244-", - "A186245-", - "T186246-", - "T186247-", - "G186248-", - "A186249-", - "C186250-", - "T186251-", - "T186252-", - "C186253-", - "A186254-", - "G186255-", - "A186256-", - "G186257-", - "G186258-", - "G186259-", - "T186260-", - "A186261-", - "G186262-", - "A186263-", - "G186264-", - "A186265-", - "A186266-", - "A186267-", - "T186268-", - "A186269-", - "G186270-", - "C186271-", - "A186272-", - "A186273-", - "G186274-", - "T186275-", - "G186276-", - "T186277-", - "T186278-", - "A186279-", - "A186280-", - "T186281-", - "A186282-", - "T186283-", - "A186284-", - "G186285-", - "A186286-", - "T186287-", - "G186288-", - "G186289-", - "T186290-", - "A186291-", - "A186292-", - "T186293-", - "C186294-", - "T186295-", - "G186296-", - "T186297-", - "T186298-", - "A186299-", - "G186300-", - "A186301-", - "T186302-", - "A186303-", - "T186304-", - "C186305-", - "G186306-", - "C186307-", - "A186308-", - "T186309-", - "A186310-", - "T186311-", - "C186312-", - "A186313-", - "A186314-", - "G186315-", - "C186316-", - "A186317-", - "G186318-", - "A186319-", - "T186320-", - "A186321-", - "A186322-", - "G186323-", - "G186324-", - "A186325-", - "A186326-", - "A186327-", - "A186328-", - "G186329-", - "A186330-", - "T186331-", - "G186332-", - "G186333-", - "C186334-", - "C186335-", - "G186336-", - "A186337-", - "C186338-", - "A186339-", - "T186340-", - "A186341-", - "C186342-", - "A186343-", - "G186344-", - "A186345-", - "C186346-", - "A186347-", - "A186348-", - "G186349-", - "A186350-", - "A186351-", - "T186352-", - "A186353-", - "A186354-", - "A186355-", - "T186356-", - "G186357-", - "A186358-", - "T186359-", - "A186360-", - "T186361-", - "T186362-", - "A186363-", - "T186364-", - "T186365-", - "A186366-", - "G186367-", - "A186368-", - "G186369-", - "A186370-", - "T186371-", - "T186372-", - "T186373-", - "G186374-", - "T186375-", - "T186376-", - "T186377-", - "A186378-", - "T186379-", - "A186380-", - "C186381-", - "A186382-", - "C186383-", - "A186384-", - "C186385-", - "T186386-", - "C186387-", - "T186388-", - "A186389-", - "T186390-", - "C186391-", - "A186392-", - "G186393-", - "A186394-", - "C186395-", - "A186396-", - "A186397-", - "A186398-", - "G186399-", - "A186400-", - "T186401-", - "A186402-", - "T186403-", - "A186404-", - "A186405-", - "A186406-", - "A186407-", - "G186408-", - "A186409-", - "C186410-", - "A186411-", - "T186412-", - "T186413-", - "A186414-", - "T186415-", - "A186416-", - "G186417-", - "A186418-", - "A186419-", - "T186420-", - "C186421-", - "C186422-", - "G186423-", - "A186424-", - "A186425-", - "G186426-", - "A186427-", - "A186428-", - "G186429-", - "G186430-", - "T186431-", - "A186432-", - "A186433-", - "G186434-", - "A186435-", - "G186436-", - "A186437-", - "T186438-", - "G186439-", - "T186440-", - "T186441-", - "G186442-", - "T186443-", - "A186444-", - "T186445-", - "A186446-", - "A186447-", - "T186448-", - "A186449-", - "G186450-", - "A186451-", - "T186452-", - "G186453-", - "T186454-", - "T186455-", - "A186456-", - "A186457-", - "G186458-", - "A186459-", - "A186460-", - "C186461-", - "A186462-", - "A186463-", - "T186464-", - "C186465-", - "T186466-", - "T186467-", - "G186468-", - "T186469-", - "T186470-", - "A186471-", - "A186472-", - "A186473-", - "A186474-", - "A186475-", - "G186476-", - "T186477-", - "A186478-", - "C186479-", - "T186480-", - "A186481-", - "T186482-", - "T186483-", - "C186484-", - "T186485-", - "A186486-", - "T186487-", - "T186488-", - "G186489-", - "A186490-", - "T186491-", - "A186492-", - "A186493-", - "T186494-", - "T186495-", - "A186496-", - "T186497-", - "C186498-", - "T186499-", - "A186500-", - "T186501-", - "G186502-", - "T186503-", - "G186504-", - "A186505-", - "T186506-", - "A186507-", - "C186508-", - "T186509-", - "T186510-", - "T186511-", - "A186512-", - "G186513-", - "A186514-", - "T186515-", - "G186516-", - "A186517-", - "T186518-", - "T186519-", - "A186520-", - "T186521-", - "A186522-", - "T186523-", - "A186524-", - "T186525-", - "A186526-", - "C186527-", - "A186528-", - "C186529-", - "C186530-", - "T186531-", - "C186532-", - "T186533-", - "G186534-", - "T186535-", - "A186536-", - "G186537-", - "A186538-", - "A186539-", - "T186540-", - "A186541-", - "T186542-", - "A186543-", - "A186544-", - "C186545-", - "A186546-", - "A186547-", - "A186548-", - "T186549-", - "C186550-", - "C186551-", - "T186552-", - "A186553-", - "T186554-", - "G186555-", - "T186556-", - "G186557-", - "T186558-", - "T186559-", - "A186560-", - "G186561-", - "T186562-", - "A186563-", - "A186564-", - "A186565-", - "C186566-", - "G186567-", - "A186568-", - "T186569-", - "A186570-", - "C186571-", - "T186572-", - "T186573-", - "A186574-", - "T186575-", - "A186576-", - "T186577-", - "G186578-", - "A186579-", - "G186580-", - "C186581-", - "T186582-", - "A186583-", - "T186584-", - "G186585-", - "A186586-", - "C186587-", - "T186588-", - "A186589-", - "T186590-", - "C186591-", - "T186592-", - "T186593-", - "G186594-", - "A186595-", - "A186596-", - "T186597-", - "C186598-", - "A186599-", - "T186600-", - "C186601-", - "A186602-", - "G186603-", - "G186604-", - "T186605-", - "G186606-", - "T186607-", - "A186608-", - "G186609-", - "T186610-", - "T186611-", - "G186612-", - "T186613-", - "T186614-", - "C186615-", - "T186616-", - "A186617-", - "T186618-", - "C186619-", - "A186620-", - "T186621-", - "G186622-", - "T186623-", - "T186624-", - "A186625-", - "T186626-", - "G186627-", - "A186628-", - "A186629-", - "A186630-", - "T186631-", - "G186632-", - "A186633-", - "C186634-", - "T186635-", - "A186636-", - "T186637-", - "A186638-", - "A186639-", - "T186640-", - "C186641-", - "T186642-", - "C186643-", - "C186644-", - "T186645-", - "T186646-", - "G186647-", - "G186648-", - "A186649-", - "T186650-", - "A186651-", - "C186652-", - "A186653-", - "A186654-", - "A186655-", - "A186656-", - "G186657-", - "A186658-", - "C186659-", - "G186660-", - "C186661-", - "C186662-", - "A186663-", - "A186664-", - "A186665-", - "G186666-", - "A186667-", - "T186668-", - "G186669-", - "C186670-", - "T186671-", - "A186672-", - "T186673-", - "A186674-", - "G186675-", - "A186676-", - "A186677-", - "G186678-", - "A186679-", - "T186680-", - "G186681-", - "T186682-", - "G186683-", - "A186684-", - "T186685-", - "A186686-", - "G186687-", - "T186688-", - "A186689-", - "G186690-", - "C186691-", - "A186692-", - "A186693-", - "G186694-", - "T186695-", - "G186696-", - "C186697-", - "G186698-", - "G186699-", - "T186700-", - "A186701-", - "G186702-", - "C186703-", - "C186704-", - "G186705-", - "A186706-", - "A186707-", - "G186708-", - "C186709-", - "A186710-", - "T186711-", - "T186712-", - "G186713-", - "A186714-", - "A186715-", - "T186716-", - "G186717-", - "A186718-", - "C186719-", - "A186720-", - "T186721-", - "G186722-", - "T186723-", - "T186724-", - "T186725-", - "A186726-", - "A186727-", - "G186728-", - "G186729-", - "A186730-", - "A186731-", - "T186732-", - "T186733-", - "T186734-", - "G186735-", - "A186736-", - "T186737-", - "A186738-", - "A186739-", - "A186740-", - "A186741-", - "A186742-", - "C186743-", - "G186744-", - "T186745-", - "A186746-", - "A186747-", - "G186748-", - "T186749-", - "G186750-", - "C186751-", - "T186752-", - "A186753-", - "T186754-", - "T186755-", - "A186756-", - "T186757-", - "A186758-", - "A186759-", - "T186760-", - "A186761-", - "A186762-", - "A186763-", - "A186764-", - "G186765-", - "A186766-", - "A186767-", - "G186768-", - "A186769-", - "A186770-", - "G186771-", - "A186772-", - "T186773-", - "A186774-", - "A186775-", - "T186776-", - "T186777-", - "A186778-", - "T186779-", - "C186780-", - "T186781-", - "A186782-", - "A186783-", - "A186784-", - "C186785-", - "A186786-", - "G186787-", - "T186788-", - "T186789-", - "C186790-", - "G186791-", - "C186792-", - "C186793-", - "C186794-", - "G186795-", - "A186796-", - "T186797-", - "A186798-", - "T186799-", - "C186800-", - "T186801-", - "A186802-", - "C186803-", - "C186804-", - "A186805-", - "T186806-", - "A186807-", - "T186808-", - "A186809-", - "A186810-", - "T186811-", - "A186812-", - "T186813-", - "A186814-", - "T186815-", - "A186816-", - "T186817-", - "C186818-", - "A186819-", - "T186820-", - "A186821-", - "G186822-", - "G186823-", - "T186824-", - "G186825-", - "G186826-", - "C186827-", - "A186828-", - "C186829-", - "T186830-", - "A186831-", - "T186832-", - "T186833-", - "C186834-", - "T186835-", - "G186836-", - "C186837-", - "T186838-", - "A186839-", - "C186840-", - "T186841-", - "G186842-", - "T186843-", - "T186844-", - "A186845-", - "G186846-", - "T186847-", - "C186848-", - "A186849-", - "T186850-", - "T186851-", - "A186852-", - "T186853-", - "T186854-", - "T186855-", - "T186856-", - "A186857-", - "A186858-", - "T186859-", - "A186860-", - "T186861-", - "T186862-", - "G186863-", - "G186864-", - "C186865-", - "A186866-", - "A186867-", - "T186868-", - "T186869-", - "T186870-", - "A186871-", - "T186872-", - "A186873-", - "T186874-", - "A186875-", - "G186876-", - "C186877-", - "G186878-", - "C186879-", - "G186880-", - "C186881-", - "A186882-", - "A186883-", - "T186884-", - "A186885-", - "A186886-", - "A186887-", - "T186888-", - "A186889-", - "C186890-", - "A186891-", - "G186892-", - "A186893-", - "A186894-", - "C186895-", - "C186896-", - "A186897-", - "G186898-", - "G186899-", - "A186900-", - "A186901-", - "A186902-", - "T186903-", - "A186904-", - "T186905-", - "G186906-", - "A186907-", - "A186908-", - "A186909-", - "T186910-", - "A186911-", - "A186912-", - "T186913-", - "G186914-", - "A186915-", - "A186916-", - "A186917-", - "T186918-", - "A186919-", - "T186920-", - "G186921-", - "A186922-", - "C186923-", - "A186924-", - "A186925-", - "T186926-", - "A186927-", - "T186928-", - "G186929-", - "A186930-", - "G186931-", - "C186932-", - "A186933-", - "T186934-", - "T186935-", - "A186936-", - "A186937-", - "A186938-", - "T186939-", - "C186940-", - "T186941-", - "G186942-", - "A186943-", - "G186944-", - "C186945-", - "A186946-", - "T186947-", - "C186948-", - "A186949-", - "T186950-", - "G186951-", - "A186952-", - "T186953-", - "A186954-", - "G186955-", - "T186956-", - "C186957-", - "T186958-", - "T186959-", - "G186960-", - "A186961-", - "A186962-", - "A186963-", - "C186964-", - "A186965-", - "G186966-", - "T186967-", - "G186968-", - "T186969-", - "C186970-", - "T186971-", - "A186972-", - "T186973-", - "G186974-", - "G186975-", - "A186976-", - "A186977-", - "A186978-", - "T186979-", - "T186980-", - "A186981-", - "T186982-", - "T186983-", - "G186984-", - "A186985-", - "T186986-", - "A186987-", - "A186988-", - "T186989-", - "C186990-", - "G186991-", - "G186992-", - "T186993-", - "A186994-", - "C186995-", - "T186996-", - "A186997-", - "A186998-", - "T186999-", - "A187000-", - "A187001-", - "A187002-", - "A187003-", - "T187004-", - "A187005-", - "G187006-", - "T187007-", - "T187008-", - "T187009-", - "A187010-", - "A187011-", - "C187012-", - "T187013-", - "C187014-", - "T187015-", - "T187016-", - "T187017-", - "T187018-", - "A187019-", - "G187020-", - "A187021-", - "A187022-", - "C187023-", - "C187024-", - "A187025-", - "G187026-", - "T187027-", - "T187028-", - "T187029-", - "G187030-", - "G187031-", - "T187032-", - "A187033-", - "C187034-", - "T187035-", - "G187036-", - "T187037-", - "A187038-", - "A187039-", - "T187040-", - "T187041-", - "T187042-", - "C187043-", - "A187044-", - "G187045-", - "T187046-", - "T187047-", - "C187048-", - "A187049-", - "T187050-", - "T187051-", - "A187052-", - "C187053-", - "T187054-", - "C187055-", - "G187056-", - "T187057-", - "T187058-", - "G187059-", - "A187060-", - "G187061-", - "A187062-", - "A187063-", - "T187064-", - "A187065-", - "T187066-", - "T187067-", - "G187068-", - "A187069-", - "T187070-", - "G187071-", - "A187072-", - "T187073-", - "T187074-", - "T187075-", - "T187076-", - "T187077-", - "T187078-", - "T187079-", - "T187080-", - "A187081-", - "A187082-", - "A187083-", - "T187084-", - "G187085-", - "A187086-", - "G187087-", - "T187088-", - "A187089-", - "T187090-", - "C187091-", - "G187092-", - "G187093-", - "T187094-", - "A187095-", - "G187096-", - "T187097-", - "T187098-", - "A187099-", - "C187100-", - "A187101-", - "T187102-", - "A187103-", - "T187104-", - "T187105-", - "A187106-", - "C187107-", - "C187108-", - "A187109-", - "T187110-", - "A187111-", - "T187112-", - "C187113-", - "A187114-", - "T187115-", - "C187116-", - "C187117-", - "A187118-", - "T187119-", - "T187120-", - "A187121-", - "T187122-", - "A187123-", - "T187124-", - "A187125-", - "A187126-", - "T187127-", - "C187128-", - "G187129-", - "A187130-", - "T187131-", - "G187132-", - "A187133-", - "T187134-", - "G187135-", - "C187136-", - "A187137-", - "T187138-", - "G187139-", - "T187140-", - "A187141-", - "T187142-", - "T187143-", - "A187144-", - "G187145-", - "A187146-", - "A187147-", - "T187148-", - "A187149-", - "C187150-", - "T187151-", - "T187152-", - "T187153-", - "C187154-", - "C187155-", - "G187156-", - "A187157-", - "A187158-", - "T187159-", - "A187160-", - "A187161-", - "G187162-", - "T187163-", - "C187164-", - "T187165-", - "T187166-", - "C187167-", - "T187168-", - "A187169-", - "A187170-", - "A187171-", - "T187172-", - "A187173-", - "T187174-", - "T187175-", - "G187176-", - "T187177-", - "A187178-", - "T187179-", - "T187180-", - "A187181-", - "A187182-", - "T187183-", - "T187184-", - "A187185-", - "T187186-", - "G187187-", - "A187188-", - "A187189-", - "A187190-", - "A187191-", - "A187192-", - "C187193-", - "T187194-", - "A187195-", - "T187196-", - "G187197-", - "C187198-", - "T187199-", - "A187200-", - "T187201-", - "G187202-", - "T187203-", - "G187204-", - "A187205-", - "G187206-", - "T187207-", - "A187208-", - "T187209-", - "G187210-", - "A187211-", - "T187212-", - "T187213-", - "C187214-", - "A187215-", - "A187216-", - "A187217-", - "G187218-", - "A187219-", - "T187220-", - "G187221-", - "T187222-", - "T187223-", - "T187224-", - "A187225-", - "A187226-", - "T187227-", - "G187228-", - "A187229-", - "T187230-", - "A187231-", - "C187232-", - "G187233-", - "A187234-", - "T187235-", - "A187236-", - "C187237-", - "T187238-", - "A187239-", - "G187240-", - "A187241-", - "T187242-", - "T187243-", - "T187244-", - "T187245-", - "A187246-", - "T187247-", - "C187248-", - "T187249-", - "C187250-", - "T187251-", - "A187252-", - "G187253-", - "C187254-", - "G187255-", - "A187256-", - "G187257-", - "A187258-", - "T187259-", - "T187260-", - "G187261-", - "T187262-", - "T187263-", - "T187264-", - "A187265-", - "G187266-", - "A187267-", - "A187268-", - "T187269-", - "C187270-", - "A187271-", - "T187272-", - "T187273-", - "T187274-", - "A187275-", - "T187276-", - "C187277-", - "A187278-", - "T187279-", - "A187280-", - "A187281-", - "C187282-", - "T187283-", - "A187284-", - "T187285-", - "G187286-", - "T187287-", - "T187288-", - "T187289-", - "A187290-", - "A187291-", - "T187292-", - "A187293-", - "A187294-", - "A187295-", - "T187296-", - "T187297-", - "C187298-", - "A187299-", - "T187300-", - "C187301-", - "A187302-", - "A187303-", - "C187304-", - "G187305-", - "A187306-", - "A187307-", - "T187308-", - "A187309-", - "T187310-", - "C187311-", - "G187312-", - "A187313-", - "T187314-", - "A187315-", - "A187316-", - "A187317-", - "G187318-", - "A187319-", - "C187320-", - "C187321-", - "T187322-", - "C187323-", - "T187324-", - "T187325-", - "G187326-", - "T187327-", - "A187328-", - "A187329-", - "T187330-", - "T187331-", - "C187332-", - "G187333-", - "A187334-", - "G187335-", - "T187336-", - "A187337-", - "T187338-", - "A187339-", - "G187340-", - "G187341-", - "A187342-", - "A187343-", - "G187344-", - "T187345-", - "A187346-", - "G187347-", - "T187348-", - "A187349-", - "T187350-", - "T187351-", - "A187352-", - "C187353-", - "C187354-", - "A187355-", - "T187356-", - "A187357-", - "T187358-", - "C187359-", - "A187360-", - "A187361-", - "C187362-", - "T187363-", - "T187364-", - "C187365-", - "C187366-", - "G187367-", - "A187368-", - "G187369-", - "T187370-", - "T187371-", - "A187372-", - "A187373-", - "C187374-", - "A187375-", - "A187376-", - "T187377-", - "T187378-", - "A187379-", - "C187380-", - "T187381-", - "C187382-", - "T187383-", - "A187384-", - "A187385-", - "A187386-", - "A187387-", - "C187388-", - "A187389-", - "T187390-", - "G187391-", - "A187392-", - "G187393-", - "G187394-", - "A187395-", - "T187396-", - "T187397-", - "G187398-", - "T187399-", - "A187400-", - "C187401-", - "T187402-", - "C187403-", - "C187404-", - "T187405-", - "G187406-", - "T187407-", - "C187408-", - "T187409-", - "T187410-", - "T187411-", - "A187412-", - "T187413-", - "T187414-", - "G187415-", - "G187416-", - "A187417-", - "G187418-", - "A187419-", - "T187420-", - "C187421-", - "A187422-", - "C187423-", - "T187424-", - "A187425-", - "T187426-", - "T187427-", - "T187428-", - "A187429-", - "G187430-", - "T187431-", - "C187432-", - "G187433-", - "T187434-", - "T187435-", - "G187436-", - "A187437-", - "T187438-", - "A187439-", - "A187440-", - "A187441-", - "C187442-", - "T187443-", - "A187444-", - "G187445-", - "T187446-", - "A187447-", - "A187448-", - "C187449-", - "C187450-", - "T187451-", - "C187452-", - "A187453-", - "G187454-", - "G187455-", - "T187456-", - "T187457-", - "T187458-", - "C187459-", - "T187460-", - "T187461-", - "T187462-", - "A187463-", - "C187464-", - "A187465-", - "A187466-", - "A187467-", - "C187468-", - "G187469-", - "A187470-", - "T187471-", - "A187472-", - "A187473-", - "A187474-", - "G187475-", - "T187476-", - "A187477-", - "C187478-", - "A187479-", - "A187480-", - "C187481-", - "A187482-", - "T187483-", - "C187484-", - "A187485-", - "A187486-", - "G187487-", - "A187488-", - "C187489-", - "C187490-", - "T187491-", - "C187492-", - "A187493-", - "C187494-", - "A187495-", - "A187496-", - "C187497-", - "A187498-", - "C187499-", - "A187500-", - "G187501-", - "T187502-", - "G187503-", - "C187504-", - "A187505-", - "A187506-", - "G187507-", - "A187508-", - "T187509-", - "T187510-", - "A187511-", - "A187512-", - "T187513-", - "C187514-", - "T187515-", - "A187516-", - "G187517-", - "A187518-", - "A187519-", - "A187520-", - "T187521-", - "C187522-", - "A187523-", - "A187524-", - "A187525-", - "T187526-", - "G187527-", - "T187528-", - "A187529-", - "A187530-", - "T187531-", - "T187532-", - "C187533-", - "T187534-", - "G187535-", - "G187536-", - "A187537-", - "G187538-", - "G187539-", - "A187540-", - "G187541-", - "A187542-", - "A187543-", - "T187544-", - "C187545-", - "T187546-", - "A187547-", - "G187548-", - "A187549-", - "C187550-", - "A187551-", - "A187552-", - "C187553-", - "T187554-", - "A187555-", - "A187556-", - "C187557-", - "A187558-", - "C187559-", - "C187560-", - "C187561-", - "A187562-", - "C187563-", - "G187564-", - "G187565-", - "C187566-", - "G187567-", - "A187568-", - "A187569-", - "G187570-", - "T187571-", - "A187572-", - "T187573-", - "A187574-", - "C187575-", - "T187576-", - "T187577-", - "T187578-", - "A187579-", - "T187580-", - "G187581-", - "C187582-", - "C187583-", - "T187584-", - "C187585-", - "A187586-", - "T187587-", - "T187588-", - "C187589-", - "A187590-", - "G187591-", - "A187592-", - "A187593-", - "A187594-", - "C187595-", - "G187596-", - "G187597-", - "T187598-", - "A187599-", - "A187600-", - "C187601-", - "T187602-", - "G187603-", - "T187604-", - "A187605-", - "G187606-", - "T187607-", - "A187608-", - "G187609-", - "G187610-", - "A187611-", - "G187612-", - "A187613-", - "C187614-", - "T187615-", - "G187616-", - "T187617-", - "C187618-", - "T187619-", - "C187620-", - "T187621-", - "C187622-", - "T187623-", - "A187624-", - "A187625-", - "T187626-", - "C187627-", - "T187628-", - "C187629-", - "G187630-", - "A187631-", - "T187632-", - "G187633-", - "T187634-", - "A187635-", - "T187636-", - "A187637-", - "T187638-", - "A187639-", - "T187640-", - "A187641-", - "A187642-", - "T187643-", - "A187644-", - "T187645-", - "A187646-", - "T187647-", - "A187648-", - "C187649-", - "C187650-", - "A187651-", - "A187652-", - "T187653-", - "A187654-", - "C187655-", - "G187656-", - "G187657-", - "A187658-", - "C187659-", - "G187660-", - "C187661-", - "G187662-", - "A187663-", - "T187664-", - "A187665-", - "T187666-", - "A187667-", - "T187668-", - "T187669-", - "C187670-", - "C187671-", - "G187672-", - "A187673-", - "C187674-", - "A187675-", - "T187676-", - "G187677-", - "A187678-", - "A187679-", - "T187680-", - "G187681-", - "G187682-", - "C187683-", - "G187684-", - "T187685-", - "C187686-", - "G187687-", - "C187688-", - "T187689-", - "T187690-", - "A187691-", - "T187692-", - "C187693-", - "A187694-", - "T187695-", - "A187696-", - "T187697-", - "G187698-", - "T187699-", - "T187700-", - "A187701-", - "T187702-", - "A187703-", - "T187704-", - "C187705-", - "C187706-", - "T187707-", - "A187708-", - "A187709-", - "A187710-", - "T187711-", - "G187712-", - "T187713-", - "T187714-", - "G187715-", - "A187716-", - "T187717-", - "C187718-", - "A187719-", - "T187720-", - "A187721-", - "T187722-", - "T187723-", - "C187724-", - "C187725-", - "A187726-", - "C187727-", - "A187728-", - "A187729-", - "A187730-", - "T187731-", - "G187732-", - "A187733-", - "T187734-", - "T187735-", - "G187736-", - "T187737-", - "G187738-", - "A187739-", - "A187740-", - "C187741-", - "G187742-", - "A187743-", - "G187744-", - "A187745-", - "T187746-", - "T187747-", - "A187748-", - "A187749-", - "A187750-", - "T187751-", - "C187752-", - "A187753-", - "T187754-", - "C187755-", - "T187756-", - "A187757-", - "A187758-", - "C187759-", - "A187760-", - "A187761-", - "A187762-", - "T187763-", - "A187764-", - "A187765-", - "T187766-", - "T187767-", - "A187768-", - "G187769-", - "T187770-", - "T187771-", - "T187772-", - "T187773-", - "T187774-", - "T187775-", - "A187776-", - "T187777-", - "G187778-", - "A187779-", - "C187780-", - "A187781-", - "T187782-", - "T187783-", - "A187784-", - "A187785-", - "C187786-", - "A187787-", - "T187788-", - "A187789-", - "T187790-", - "A187791-", - "A187792-", - "T187793-", - "A187794-", - "A187795-", - "A187796-", - "T187797-", - "A187798-", - "A187799-", - "A187800-", - "T187801-", - "T187802-", - "A187803-", - "A187804-", - "T187805-", - "C187806-", - "A187807-", - "T187808-", - "T187809-", - "A187810-", - "T187811-", - "T187812-", - "G187813-", - "A187814-", - "C187815-", - "T187816-", - "T187817-", - "A187818-", - "A187819-", - "C187820-", - "G187821-", - "A187822-", - "T187823-", - "G187824-", - "A187825-", - "C187826-", - "G187827-", - "A187828-", - "A187829-", - "A187830-", - "G187831-", - "T187832-", - "T187833-", - "A187834-", - "T187835-", - "C187836-", - "A187837-", - "T187838-", - "T187839-", - "A187840-", - "T187841-", - "C187842-", - "T187843-", - "T187844-", - "A187845-", - "G187846-", - "G187847-", - "A187848-", - "T187849-", - "T187850-", - "C187851-", - "T187852-", - "T187853-", - "G187854-", - "A187855-", - "T187856-", - "T187857-", - "A187858-", - "T187859-", - "T187860-", - "A187861-", - "A187862-", - "T187863-", - "A187864-", - "C187865-", - "A187866-", - "A187867-", - "A187868-", - "T187869-", - "T187870-", - "C187871-", - "G187872-", - "T187873-", - "T187874-", - "G187875-", - "T187876-", - "G187877-", - "T187878-", - "C187879-", - "T187880-", - "A187881-", - "T187882-", - "G187883-", - "A187884-", - "A187885-", - "A187886-", - "T187887-", - "G187888-", - "T187889-", - "G187890-", - "A187891-", - "A187892-", - "C187893-", - "A187894-", - "A187895-", - "G187896-", - "G187897-", - "T187898-", - "G187899-", - "T187900-", - "C187901-", - "T187902-", - "C187903-", - "A187904-", - "T187905-", - "A187906-", - "T187907-", - "T187908-", - "A187909-", - "T187910-", - "A187911-", - "A187912-", - "T187913-", - "G187914-", - "C187915-", - "A187916-", - "C187917-", - "A187918-", - "A187919-", - "G187920-", - "A187921-", - "A187922-", - "T187923-", - "T187924-", - "A187925-", - "A187926-", - "A187927-", - "G187928-", - "T187929-", - "G187930-", - "T187931-", - "T187932-", - "G187933-", - "T187934-", - "A187935-", - "A187936-", - "A187937-", - "C187938-", - "T187939-", - "A187940-", - "T187941-", - "C187942-", - "T187943-", - "A187944-", - "G187945-", - "C187946-", - "C187947-", - "A187948-", - "G187949-", - "G187950-", - "A187951-", - "A187952-", - "C187953-", - "A187954-", - "T187955-", - "A187956-", - "T187957-", - "T187958-", - "C187959-", - "A187960-", - "G187961-", - "A187962-", - "T187963-", - "T187964-", - "A187965-", - "T187966-", - "C187967-", - "G187968-", - "A187969-", - "T187970-", - "G187971-", - "T187972-", - "G187973-", - "A187974-", - "T187975-", - "A187976-", - "A187977-", - "A187978-", - "T187979-", - "A187980-", - "C187981-", - "A187982-", - "G187983-", - "C187984-", - "G187985-", - "A187986-", - "T187987-", - "A187988-", - "C187989-", - "C187990-", - "A187991-", - "T187992-", - "C187993-", - "T187994-", - "G187995-", - "T187996-", - "G187997-", - "G187998-", - "A187999-", - "C188000-", - "A188001-", - "T188002-", - "T188003-", - "G188004-", - "T188005-", - "C188006-", - "C188007-", - "A188008-", - "A188009-", - "G188010-", - "T188011-", - "G188012-", - "A188013-", - "C188014-", - "A188015-", - "C188016-", - "A188017-", - "T188018-", - "T188019-", - "C188020-", - "A188021-", - "C188022-", - "G188023-", - "T188024-", - "C188025-", - "A188026-", - "A188027-", - "T188028-", - "A188029-", - "T188030-", - "A188031-", - "T188032-", - "A188033-", - "A188034-", - "T188035-", - "C188036-", - "G188037-", - "T188038-", - "T188039-", - "C188040-", - "T188041-", - "C188042-", - "C188043-", - "T188044-", - "C188045-", - "G188046-", - "G188047-", - "T188048-", - "G188049-", - "T188050-", - "C188051-", - "A188052-", - "T188053-", - "A188054-", - "G188055-", - "T188056-", - "T188057-", - "G188058-", - "T188059-", - "A188060-", - "G188061-", - "A188062-", - "G188063-", - "G188064-", - "T188065-", - "C188066-", - "A188067-", - "C188068-", - "A188069-", - "C188070-", - "C188071-", - "T188072-", - "T188073-", - "G188074-", - "T188075-", - "A188076-", - "C188077-", - "A188078-", - "C188079-", - "C188080-", - "T188081-", - "A188082-", - "C188083-", - "C188084-", - "A188085-", - "C188086-", - "A188087-", - "A188088-", - "A188089-", - "T188090-", - "A188091-", - "G188092-", - "A188093-", - "A188094-", - "T188095-", - "A188096-", - "T188097-", - "G188098-", - "T188099-", - "C188100-", - "A188101-", - "T188102-", - "T188103-", - "G188104-", - "T188105-", - "G188106-", - "A188107-", - "C188108-", - "T188109-", - "C188110-", - "G188111-", - "A188112-", - "A188113-", - "T188114-", - "A188115-", - "G188116-", - "T188117-", - "T188118-", - "A188119-", - "T188120-", - "C188121-", - "G188122-", - "T188123-", - "C188124-", - "T188125-", - "C188126-", - "C188127-", - "T188128-", - "T188129-", - "A188130-", - "A188131-", - "A188132-", - "G188133-", - "C188134-", - "T188135-", - "T188136-", - "C188137-", - "T188138-", - "G188139-", - "A188140-", - "T188141-", - "G188142-", - "G188143-", - "T188144-", - "A188145-", - "A188146-", - "C188147-", - "T188148-", - "G188149-", - "T188150-", - "G188151-", - "T188152-", - "T188153-", - "A188154-", - "C188155-", - "A188156-", - "T188157-", - "G188158-", - "T188159-", - "G188160-", - "C188161-", - "T188162-", - "C188163-", - "C188164-", - "T188165-", - "A188166-", - "A188167-", - "A188168-", - "A188169-", - "C188170-", - "A188171-", - "A188172-", - "A188173-", - "A188174-", - "T188175-", - "A188176-", - "T188177-", - "G188178-", - "G188179-", - "T188180-", - "C188181-", - "G188182-", - "T188183-", - "G188184-", - "T188185-", - "G188186-", - "T188187-", - "A188188-", - "C188189-", - "G188190-", - "G188191-", - "A188192-", - "A188193-", - "A188194-", - "G188195-", - "A188196-", - "A188197-", - "A188198-", - "G188199-", - "G188200-", - "A188201-", - "G188202-", - "A188203-", - "A188204-", - "A188205-", - "A188206-", - "T188207-", - "G188208-", - "A188209-", - "T188210-", - "A188211-", - "T188212-", - "G188213-", - "G188214-", - "A188215-", - "A188216-", - "T188217-", - "A188218-", - "C188219-", - "C188220-", - "A188221-", - "T188222-", - "T188223-", - "T188224-", - "G188225-", - "T188226-", - "A188227-", - "A188228-", - "G188229-", - "A188230-", - "A188231-", - "A188232-", - "T188233-", - "G188234-", - "T188235-", - "C188236-", - "G188237-", - "G188238-", - "A188239-", - "A188240-", - "G188241-", - "G188242-", - "G188243-", - "T188244-", - "A188245-", - "C188246-", - "T188247-", - "T188248-", - "A188249-", - "T188250-", - "T188251-", - "C188252-", - "A188253-", - "G188254-", - "A188255-", - "T188256-", - "A188257-", - "T188258-", - "T188259-", - "G188260-", - "T188261-", - "A188262-", - "T188263-", - "C188264-", - "T188265-", - "G188266-", - "A188267-", - "C188268-", - "T188269-", - "C188270-", - "T188271-", - "G188272-", - "A188273-", - "T188274-", - "C188275-", - "A188276-", - "A188277-", - "T188278-", - "G188279-", - "T188280-", - "A188281-", - "A188282-", - "A188283-", - "C188284-", - "C188285-", - "T188286-", - "A188287-", - "T188288-", - "G188289-", - "A188290-", - "C188291-", - "A188292-", - "A188293-", - "G188294-", - "A188295-", - "T188296-", - "A188297-", - "A188298-", - "G188299-", - "A188300-", - "C188301-", - "T188302-", - "T188303-", - "A188304-", - "C188305-", - "T188306-", - "C188307-", - "G188308-", - "C188309-", - "A188310-", - "T188311-", - "C188312-", - "T188313-", - "A188314-", - "C188315-", - "T188316-", - "G188317-", - "G188318-", - "A188319-", - "T188320-", - "A188321-", - "G188322-", - "A188323-", - "C188324-", - "A188325-", - "T188326-", - "A188327-", - "A188328-", - "A188329-", - "T188330-", - "A188331-", - "T188332-", - "C188333-", - "C188334-", - "T188335-", - "C188336-", - "C188337-", - "T188338-", - "C188339-", - "G188340-", - "T188341-", - "A188342-", - "A188343-", - "T188344-", - "A188345-", - "A188346-", - "T188347-", - "G188348-", - "A188349-", - "A188350-", - "A188351-", - "T188352-", - "A188353-", - "T188354-", - "A188355-", - "A188356-", - "T188357-", - "A188358-", - "T188359-", - "A188360-", - "C188361-", - "A188362-", - "C188363-", - "T188364-", - "A188365-", - "A188366-", - "T188367-", - "T188368-", - "A188369-", - "T188370-", - "T188371-", - "A188372-", - "A188373-", - "T188374-", - "A188375-", - "T188376-", - "C188377-", - "A188378-", - "A188379-", - "T188380-", - "C188381-", - "G188382-", - "A188383-", - "G188384-", - "T188385-", - "A188386-", - "T188387-", - "T188388-", - "A188389-", - "A188390-", - "C188391-", - "A188392-", - "T188393-", - "A188394-", - "T188395-", - "A188396-", - "A188397-", - "G188398-", - "T188399-", - "T188400-", - "A188401-", - "T188402-", - "T188403-", - "T188404-", - "T188405-", - "T188406-", - "A188407-", - "A188408-", - "A188409-", - "C188410-", - "C188411-", - "C188412-", - "C188413-", - "T188414-", - "T188415-", - "T188416-", - "T188417-", - "G188418-", - "G188419-", - "G188420-", - "T188421-", - "T188422-", - "C188423-", - "C188424-", - "G188425-", - "T188426-", - "C188427-", - "C188428-", - "T188429-", - "A188430-", - "A188431-", - "A188432-", - "C188433-", - "G188434-", - "G188435-", - "C188436-", - "G188437-", - "T188438-", - "T188439-", - "T188440-", - "C188441-", - "G188442-", - "G188443-", - "T188444-", - "C188445-", - "T188446-", - "G188447-", - "T188448-", - "G188449-", - "T188450-", - "C188451-", - "G188452-", - "C188453-", - "C188454-", - "A188455-", - "C188456-", - "C188457-", - "A188458-", - "T188459-", - "G188460-", - "G188461-", - "T188462-", - "C188463-", - "A188464-", - "C188465-", - "A188466-", - "C188467-", - "C188468-", - "G188469-", - "A188470-", - "G188471-", - "C188472-", - "C188473-", - "T188474-", - "C188475-", - "T188476-", - "G188477-", - "C188478-", - "G188479-", - "T188480-", - "G188481-", - "C188482-", - "T188483-", - "C188484-", - "C188485-", - "T188486-", - "C188487-", - "C188488-", - "A188489-", - "T188490-", - "C188491-", - "G188492-", - "A188493-", - "G188494-", - "G188495-", - "A188496-", - "C188497-", - "G188498-", - "A188499-", - "C188500-", - "T188501-", - "T188502-", - "C188503-", - "A188504-", - "A188505-", - "C188506-", - "T188507-", - "A188508-", - "T188509-", - "G188510-", - "A188511-", - "C188512-", - "A188513-", - "G188514-", - "C188515-", - "T188516-", - "C188517-", - "G188518-", - "G188519-", - "T188520-", - "G188521-", - "G188522-", - "C188523-", - "G188524-", - "T188525-", - "C188526-", - "T188527-", - "G188528-", - "C188529-", - "C188530-", - "A188531-", - "G188532-", - "C188533-", - "G188534-", - "T188535-", - "G188536-", - "T188537-", - "A188538-", - "C188539-", - "A188540-", - "T188541-", - "A188542-", - "C188543-", - "G188544-", - "A188545-", - "A188546-", - "T188547-", - "G188548-", - "G188549-", - "C188550-", - "A188551-", - "T188552-", - "T188553-", - "T188554-", - "C188555-", - "T188556-", - "A188557-", - "A188558-", - "G188559-", - "A188560-", - "A188561-", - "A188562-", - "A188563-", - "G188564-", - "T188565-", - "C188566-", - "T188567-", - "A188568-", - "C188569-", - "G188570-", - "G188571-", - "T188572-", - "A188573-", - "T188574-", - "C188575-", - "C188576-", - "T188577-", - "T188578-", - "T188579-", - "C188580-", - "T188581-", - "A188582-", - "C188583-", - "A188584-", - "A188585-", - "T188586-", - "T188587-", - "T188588-", - "C188589-", - "C188590-", - "T188591-", - "T188592-", - "T188593-", - "A188594-", - "A188595-", - "C188596-", - "A188597-", - "A188598-", - "C188599-", - "G188600-", - "G188601-", - "C188602-", - "A188603-", - "A188604-", - "C188605-", - "A188606-", - "G188607-", - "C188608-", - "T188609-", - "G188610-", - "C188611-", - "A188612-", - "G188613-", - "T188614-", - "A188615-", - "T188616-", - "T188617-", - "T188618-", - "T188619-", - "T188620-", - "A188621-", - "T188622-", - "A188623-", - "C188624-", - "T188625-", - "T188626-", - "T188627-", - "G188628-", - "A188629-", - "A188630-", - "T188631-", - "G188632-", - "C188633-", - "A188634-", - "T188635-", - "C188636-", - "G188637-", - "G188638-", - "A188639-", - "C188640-", - "A188641-", - "T188642-", - "T188643-", - "T188644-", - "A188645-", - "T188646-", - "A188647-", - "C188648-", - "A188649-", - "A188650-", - "G188651-", - "G188652-", - "G188653-", - "A188654-", - "G188655-", - "T188656-", - "C188657-", - "C188658-", - "T188659-", - "G188660-", - "T188661-", - "T188662-", - "C188663-", - "T188664-", - "A188665-", - "A188666-", - "T188667-", - "A188668-", - "T188669-", - "T188670-", - "G188671-", - "G188672-", - "C188673-", - "A188674-", - "T188675-", - "C188676-", - "A188677-", - "A188678-", - "T188679-", - "G188680-", - "T188681-", - "T188682-", - "C188683-", - "G188684-", - "G188685-", - "A188686-", - "T188687-", - "C188688-", - "T188689-", - "A188690-", - "T188691-", - "A188692-", - "G188693-", - "G188694-", - "C188695-", - "T188696-", - "T188697-", - "G188698-", - "A188699-", - "T188700-", - "T188701-", - "T188702-", - "T188703-", - "C188704-", - "G188705-", - "C188706-", - "A188707-", - "T188708-", - "T188709-", - "G188710-", - "A188711-", - "C188712-", - "T188713-", - "T188714-", - "T188715-", - "A188716-", - "C188717-", - "A188718-", - "C188719-", - "A188720-", - "G188721-", - "A188722-", - "C188723-", - "A188724-", - "T188725-", - "G188726-", - "A188727-", - "A188728-", - "C188729-", - "A188730-", - "T188731-", - "C188732-", - "C188733-", - "C188734-", - "C188735-", - "T188736-", - "G188737-", - "A188738-", - "A188739-", - "T188740-", - "C188741-", - "T188742-", - "G188743-", - "T188744-", - "A188745-", - "C188746-", - "A188747-", - "T188748-", - "A188749-", - "C188750-", - "T188751-", - "T188752-", - "T188753-", - "G188754-", - "T188755-", - "G188756-", - "G188757-", - "A188758-", - "T188759-", - "T188760-", - "T188761-", - "A188762-", - "C188763-", - "A188764-", - "C188765-", - "T188766-", - "G188767-", - "T188768-", - "T188769-", - "A188770-", - "G188771-", - "A188772-", - "A188773-", - "T188774-", - "C188775-", - "T188776-", - "C188777-", - "T188778-", - "A188779-", - "A188780-", - "C188781-", - "G188782-", - "C188783-", - "T188784-", - "G188785-", - "G188786-", - "C188787-", - "C188788-", - "T188789-", - "C188790-", - "T188791-", - "G188792-", - "T188793-", - "T188794-", - "G188795-", - "T188796-", - "T188797-", - "A188798-", - "C188799-", - "T188800-", - "T188801-", - "T188802-", - "C188803-", - "T188804-", - "A188805-", - "T188806-", - "G188807-", - "A188808-", - "T188809-", - "G188810-", - "C188811-", - "A188812-", - "C188813-", - "G188814-", - "T188815-", - "A188816-", - "T188817-", - "C188818-", - "G188819-", - "T188820-", - "T188821-", - "A188822-", - "T188823-", - "G188824-", - "C188825-", - "A188826-", - "A188827-", - "G188828-", - "C188829-", - "T188830-", - "T188831-", - "T188832-", - "C188833-", - "A188834-", - "T188835-", - "G188836-", - "T188837-", - "T188838-", - "G188839-", - "A188840-", - "C188841-", - "T188842-", - "A188843-", - "C188844-", - "T188845-", - "G188846-", - "C188847-", - "A188848-", - "G188849-", - "T188850-", - "G188851-", - "T188852-", - "T188853-", - "T188854-", - "C188855-", - "T188856-", - "T188857-", - "G188858-", - "C188859-", - "T188860-", - "C188861-", - "T188862-", - "G188863-", - "A188864-", - "C188865-", - "T188866-", - "A188867-", - "C188868-", - "A188869-", - "T188870-", - "A188871-", - "T188872-", - "A188873-", - "C188874-", - "T188875-", - "C188876-", - "T188877-", - "A188878-", - "C188879-", - "A188880-", - "A188881-", - "T188882-", - "C188883-", - "A188884-", - "A188885-", - "A188886-", - "G188887-", - "A188888-", - "G188889-", - "A188890-", - "G188891-", - "A188892-", - "T188893-", - "T188894-", - "T188895-", - "C188896-", - "A188897-", - "G188898-", - "T188899-", - "A188900-", - "A188901-", - "A188902-", - "C188903-", - "T188904-", - "T188905-", - "G188906-", - "T188907-", - "A188908-", - "A188909-", - "C188910-", - "A188911-", - "G188912-", - "G188913-", - "A188914-", - "T188915-", - "T188916-", - "G188917-", - "T188918-", - "T188919-", - "T188920-", - "G188921-", - "C188922-", - "T188923-", - "G188924-", - "C188925-", - "T188926-", - "T188927-", - "T188928-", - "C188929-", - "T188930-", - "G188931-", - "G188932-", - "-196602A" - ], - "OPG015": [ - "M1-", - "E2-", - "S3-", - "V4-", - "D5-", - "F6-", - "M7-", - "A8-", - "V9-", - "D10-", - "E11-", - "Q12-", - "F13-", - "H14-", - "D15-", - "D16-", - "L17-", - "D18-", - "L19-", - "W20-", - "S21-", - "L22-", - "S23-", - "L24-", - "V25-", - "D26-", - "D27-", - "Y28-", - "K29-", - "K30-", - "H31-", - "G32-", - "L33-", - "G34-", - "V35-", - "D36-", - "C37-", - "Y38-", - "V39-", - "L40-", - "E41-", - "P42-", - "V43-", - "V44-", - "D45-", - "R46-", - "K47-", - "I48-", - "F49-", - "D50-", - "R51-", - "F52-", - "L53-", - "L54-", - "E55-", - "P56-", - "I57-", - "C58-", - "D59-", - "P60-", - "V61-", - "D62-", - "V63-", - "L64-", - "Y65-", - "D66-", - "Y67-", - "F68-", - "R69-", - "I70-", - "H71-", - "R72-", - "D73-", - "N74-", - "I75-", - "D76-", - "Q77-", - "Y78-", - "I79-", - "V80-", - "D81-", - "R82-", - "L83-", - "F84-", - "A85-", - "Y86-", - "I87-", - "T88-", - "Y89-", - "K90-", - "D91-", - "I92-", - "I93-", - "S94-", - "A95-", - "L96-", - "V97-", - "S98-", - "K99-", - "N100-", - "Y101-", - "M102-", - "E103-", - "D104-", - "I105-", - "F106-", - "S107-", - "I108-", - "I109-", - "I110-", - "K111-", - "N112-", - "C113-", - "N114-", - "S115-", - "V116-", - "Q117-", - "D118-", - "L119-", - "L120-", - "L121-", - "Y122-", - "Y123-", - "L124-", - "S125-", - "N126-", - "A127-", - "Y128-", - "V129-", - "E130-", - "I131-", - "D132-", - "I133-", - "V134-", - "D135-", - "L136-", - "M137-", - "V138-", - "D139-", - "H140-", - "G141-", - "A142-", - "V143-", - "I144-", - "Y145-", - "K146-", - "I147-", - "E148-", - "C149-", - "L150-", - "N151-", - "A152-", - "Y153-", - "F154-", - "R155-", - "G156-", - "I157-", - "C158-", - "K159-", - "K160-", - "E161-", - "S162-", - "S163-", - "V164-", - "V165-", - "E166-", - "F167-", - "I168-", - "L169-", - "N170-", - "C171-", - "G172-", - "I173-", - "P174-", - "D175-", - "E176-", - "N177-", - "D178-", - "V179-", - "K180-", - "L181-", - "D182-", - "L183-", - "Y184-", - "K185-", - "I186-", - "I187-", - "Q188-", - "Y189-", - "T190-", - "R191-", - "G192-", - "F193-", - "L194-", - "V195-", - "D196-", - "E197-", - "P198-", - "T199-", - "V200-", - "L201-", - "E202-", - "I203-", - "Y204-", - "K205-", - "L206-", - "C207-", - "I208-", - "P209-", - "Y210-", - "I211-", - "E212-", - "D213-", - "I214-", - "N215-", - "Q216-", - "L217-", - "D218-", - "A219-", - "G220-", - "G221-", - "R222-", - "T223-", - "L224-", - "L225-", - "Y226-", - "R227-", - "A228-", - "I229-", - "Y230-", - "A231-", - "G232-", - "Y233-", - "I234-", - "D235-", - "L236-", - "V237-", - "S238-", - "W239-", - "L240-", - "L241-", - "E242-", - "N243-", - "G244-", - "A245-", - "N246-", - "V247-", - "N248-", - "A249-", - "V250-", - "M251-", - "S252-", - "N253-", - "G254-", - "Y255-", - "T256-", - "C257-", - "L258-", - "D259-", - "V260-", - "A261-", - "V262-", - "D263-", - "R264-", - "G265-", - "S266-", - "V267-", - "I268-", - "A269-", - "R270-", - "R271-", - "E272-", - "A273-", - "H274-", - "L275-", - "K276-", - "I277-", - "L278-", - "E279-", - "I280-", - "L281-", - "L282-", - "R283-", - "E284-", - "P285-", - "L286-", - "S287-", - "I288-", - "D289-", - "C290-", - "I291-", - "K292-", - "L293-", - "A294-", - "I295-", - "L296-", - "N297-", - "N298-", - "T299-", - "I300-", - "E301-", - "N302-", - "H303-", - "D304-", - "V305-", - "I306-", - "K307-", - "L308-", - "C309-", - "I310-", - "K311-", - "Y312-", - "F313-", - "M314-", - "M315-", - "V316-", - "D317-", - "Y318-", - "S319-", - "L320-", - "C321-", - "N322-", - "V323-", - "Y324-", - "A325-", - "S326-", - "S327-", - "L328-", - "F329-", - "D330-", - "Y331-", - "I332-", - "I333-", - "D334-", - "C335-", - "K336-", - "Q337-", - "E338-", - "L339-", - "E340-", - "Y341-", - "I342-", - "R343-", - "Q344-", - "M345-", - "K346-", - "I347-", - "H348-", - "N349-", - "T350-", - "T351-", - "M352-", - "Y353-", - "E354-", - "L355-", - "I356-", - "Y357-", - "N358-", - "R359-", - "D360-", - "K361-", - "N362-", - "K363-", - "H364-", - "A365-", - "S366-", - "H367-", - "I368-", - "L369-", - "H370-", - "R371-", - "Y372-", - "S373-", - "K374-", - "H375-", - "P376-", - "V377-", - "L378-", - "T379-", - "Q380-", - "C381-", - "I382-", - "T383-", - "K384-", - "G385-", - "F386-", - "K387-", - "I388-", - "Y389-", - "T390-", - "E391-", - "V392-", - "T393-", - "E394-", - "Q395-", - "V396-", - "T397-", - "K398-", - "A399-", - "L400-", - "N401-", - "R402-", - "R403-", - "A404-", - "L405-", - "I406-", - "D407-", - "E408-", - "I409-", - "I410-", - "N411-", - "N412-", - "V413-", - "S414-", - "T415-", - "D416-", - "D417-", - "N418-", - "L419-", - "L420-", - "S421-", - "K422-", - "L423-", - "P424-", - "L425-", - "E426-", - "I427-", - "R428-", - "D429-", - "L430-", - "I431-", - "V432-", - "S433-", - "Q434-", - "A435-", - "V436-", - "I437-", - "*438-" - ], - "OPG019": [ - "M1-", - "S2-", - "I3-", - "K4-", - "Y5-", - "L6-", - "M7-", - "L8-", - "L9-", - "F10-", - "A11-", - "A12-", - "M13-", - "I14-", - "I15-", - "R16-", - "S17-", - "L18-", - "A19-", - "D20-", - "S21-", - "G22-", - "N23-", - "A24-", - "I25-", - "E26-", - "T27-", - "T28-", - "S29-", - "P30-", - "E31-", - "I32-", - "T33-", - "N34-", - "A35-", - "T36-", - "T37-", - "D38-", - "I39-", - "P40-", - "A41-", - "I42-", - "R43-", - "L44-", - "C45-", - "G46-", - "P47-", - "E48-", - "G49-", - "D50-", - "G51-", - "Y52-", - "C53-", - "L54-", - "H55-", - "G56-", - "D57-", - "C58-", - "I59-", - "H60-", - "A61-", - "R62-", - "D63-", - "I64-", - "D65-", - "G66-", - "M67-", - "Y68-", - "C69-", - "R70-", - "C71-", - "S72-", - "H73-", - "G74-", - "Y75-", - "T76-", - "G77-", - "I78-", - "R79-", - "C80-", - "Q81-", - "H82-", - "V83-", - "V84-", - "L85-", - "V86-", - "D87-", - "Y88-", - "Q89-", - "R90-", - "S91-", - "G92-", - "K93-", - "P94-", - "D95-", - "T96-", - "T97-", - "T98-", - "S99-", - "Y100-", - "I101-", - "P102-", - "S103-", - "L104-", - "G105-", - "I106-", - "V107-", - "L108-", - "V109-", - "L110-", - "V111-", - "G112-", - "I113-", - "I114-", - "I115-", - "T116-", - "C117-", - "C118-", - "L119-", - "L120-", - "S121-", - "V122-", - "Y123-", - "M124-", - "F125-", - "T126-", - "R127-", - "R128-", - "T129-", - "K130-", - "L131-", - "P132-", - "I133-", - "Q134-", - "D135-", - "M136-", - "V137-", - "V138-", - "L139-", - "Y140-", - "F141-", - "L142-", - "*143-" - ], - "OPG021": [ - "M1-", - "E2-", - "F3-", - "D4-", - "P5-", - "V6-", - "K7-", - "I8-", - "N9-", - "T10-", - "S11-", - "S12-", - "I13-", - "D14-", - "H15-", - "V16-", - "T17-", - "I18-", - "L19-", - "Q20-", - "Y21-", - "I22-", - "D23-", - "E24-", - "P25-", - "N26-", - "D27-", - "I28-", - "R29-", - "L30-", - "T31-", - "V32-", - "C33-", - "I34-", - "I35-", - "R36-", - "N37-", - "V38-", - "N39-", - "N40-", - "I41-", - "T42-", - "Y43-", - "Y44-", - "I45-", - "N46-", - "I47-", - "T48-", - "K49-", - "I50-", - "N51-", - "P52-", - "H53-", - "L54-", - "A55-", - "N56-", - "R57-", - "F58-", - "R59-", - "A60-", - "W61-", - "K62-", - "K63-", - "R64-", - "I65-", - "A66-", - "G67-", - "R68-", - "D69-", - "Y70-", - "M71-", - "T72-", - "N73-", - "L74-", - "S75-", - "R76-", - "D77-", - "T78-", - "G79-", - "I80-", - "Q81-", - "Q82-", - "S83-", - "K84-", - "L85-", - "T86-", - "E87-", - "T88-", - "I89-", - "R90-", - "N91-", - "C92-", - "Q93-", - "K94-", - "N95-", - "K96-", - "N97-", - "I98-", - "Y99-", - "G100-", - "L101-", - "Y102-", - "I103-", - "H104-", - "Y105-", - "N106-", - "L107-", - "V108-", - "I109-", - "N110-", - "V111-", - "V112-", - "I113-", - "D114-", - "W115-", - "I116-", - "T117-", - "D118-", - "V119-", - "I120-", - "V121-", - "Q122-", - "S123-", - "I124-", - "L125-", - "R126-", - "G127-", - "L128-", - "V129-", - "N130-", - "W131-", - "Y132-", - "I133-", - "A134-", - "N135-", - "N136-", - "T137-", - "Y138-", - "T139-", - "P140-", - "N141-", - "T142-", - "P143-", - "N144-", - "N145-", - "T146-", - "T147-", - "T148-", - "I149-", - "S150-", - "E151-", - "L152-", - "D153-", - "I154-", - "I155-", - "K156-", - "I157-", - "L158-", - "D159-", - "K160-", - "Y161-", - "E162-", - "D163-", - "M164-", - "Y165-", - "R166-", - "V167-", - "S168-", - "K169-", - "E170-", - "K171-", - "E172-", - "C173-", - "G174-", - "I175-", - "C176-", - "Y177-", - "E178-", - "V179-", - "V180-", - "Y181-", - "S182-", - "K183-", - "R184-", - "L185-", - "E186-", - "N187-", - "D188-", - "R189-", - "Y190-", - "F191-", - "G192-", - "L193-", - "L194-", - "D195-", - "S196-", - "C197-", - "N198-", - "H199-", - "I200-", - "F201-", - "C202-", - "I203-", - "T204-", - "C205-", - "I206-", - "N207-", - "I208-", - "W209-", - "H210-", - "R211-", - "T212-", - "R213-", - "R214-", - "E215-", - "T216-", - "G217-", - "A218-", - "S219-", - "D220-", - "N221-", - "C222-", - "P223-", - "I224-", - "C225-", - "R226-", - "T227-", - "R228-", - "F229-", - "K230-", - "K231-", - "I232-", - "T233-", - "M234-", - "S235-", - "K236-", - "F237-", - "Y238-", - "K239-", - "L240-", - "V241-", - "N242-", - "*243-" - ], - "OPG022": [ - "M1-", - "R2-", - "I3-", - "L4-", - "F5-", - "L6-", - "I7-", - "A8-", - "F9-", - "M10-", - "Y11-", - "G12-", - "C13-", - "V14-", - "H15-", - "S16-", - "Y17-", - "V18-", - "N19-", - "A20-", - "V21-", - "E22-", - "T23-", - "K24-", - "C25-", - "P26-", - "N27-", - "L28-", - "A29-", - "I30-", - "V31-", - "T32-", - "S33-", - "S34-", - "G35-", - "E36-", - "F37-", - "H38-", - "C39-", - "S40-", - "G41-", - "C42-", - "V43-", - "E44-", - "R45-", - "M46-", - "P47-", - "G48-", - "F49-", - "S50-", - "Y51-", - "M52-", - "Y53-", - "W54-", - "L55-", - "A56-", - "N57-", - "D58-", - "M59-", - "K60-", - "S61-", - "D62-", - "E63-", - "D64-", - "T65-", - "K66-", - "F67-", - "I68-", - "E69-", - "H70-", - "L71-", - "G72-", - "G73-", - "G74-", - "I75-", - "K76-", - "E77-", - "D78-", - "E79-", - "T80-", - "V81-", - "R82-", - "T83-", - "T84-", - "D85-", - "G86-", - "G87-", - "I88-", - "T89-", - "T90-", - "L91-", - "R92-", - "K93-", - "V94-", - "L95-", - "H96-", - "V97-", - "T98-", - "D99-", - "T100-", - "N101-", - "K102-", - "F103-", - "A104-", - "H105-", - "Y106-", - "R107-", - "F108-", - "T109-", - "C110-", - "V111-", - "L112-", - "I113-", - "T114-", - "L115-", - "D116-", - "G117-", - "V118-", - "S119-", - "K120-", - "K121-", - "N122-", - "I123-", - "W124-", - "L125-", - "K126-", - "*127-" - ], - "OPG023": [ - "D392N", - "G394-", - "E395-", - "I396-", - "P397-", - "I398-", - "G399-", - "H400-", - "L401-", - "C402-", - "E403-", - "S404-", - "N405-", - "Y406-", - "G407-", - "C408-", - "Y409-", - "N410-", - "F411-", - "Y412-", - "T413-", - "Y414-", - "T415-", - "Y416-", - "K417-", - "K418-", - "G419-", - "L420-", - "C421-", - "D422-", - "M423-", - "S424-", - "Y425-", - "V426-", - "C427-", - "P428-", - "I429-", - "L430-", - "S431-", - "T432-", - "I433-", - "N434-", - "I435-", - "C436-", - "L437-", - "P438-", - "Y439-", - "L440-", - "K441-", - "D442-", - "I443-", - "N444-", - "M445-", - "I446-", - "D447-", - "K448-", - "R449-", - "G450-", - "E451-", - "T452-", - "L453-", - "L454-", - "H455-", - "K456-", - "A457-", - "V458-", - "R459-", - "Y460-", - "N461-", - "K462-", - "Q463-", - "S464-", - "L465-", - "V466-", - "S467-", - "L468-", - "L469-", - "L470-", - "E471-", - "S472-", - "G473-", - "S474-", - "D475-", - "V476-", - "N477-", - "I478-", - "R479-", - "S480-", - "N481-", - "N482-", - "G483-", - "Y484-", - "T485-", - "C486-", - "I487-", - "T488-", - "I489-", - "A490-", - "I491-", - "N492-", - "E493-", - "S494-", - "R495-", - "N496-", - "I497-", - "E498-", - "L499-", - "L500-", - "K501-", - "M502-", - "L503-", - "L504-", - "C505-", - "H506-", - "K507-", - "P508-", - "T509-", - "L510-", - "D511-", - "C512-", - "V513-", - "I514-", - "D515-", - "S516-", - "L517-", - "S518-", - "E519-", - "V520-", - "S521-", - "N522-", - "I523-", - "V524-", - "D525-", - "N526-", - "A527-", - "Y528-", - "A529-", - "I530-", - "K531-", - "Q532-", - "C533-", - "I534-", - "K535-", - "Y536-", - "T537-", - "M538-", - "I539-", - "I540-", - "D541-", - "D542-", - "C543-", - "T544-", - "S545-", - "S546-", - "K547-", - "I548-", - "P549-", - "E550-", - "S551-", - "I552-", - "S553-", - "Q554-", - "R555-", - "Y556-", - "N557-", - "D558-", - "Y559-", - "I560-", - "D561-", - "L562-", - "C563-", - "N564-", - "Q565-", - "E566-", - "L567-", - "N568-", - "E569-", - "M570-", - "K571-", - "K572-", - "I573-", - "M574-", - "V575-", - "G576-", - "G577-", - "N578-", - "T579-", - "M580-", - "F581-", - "S582-", - "L583-", - "I584-", - "F585-", - "T586-", - "E587-", - "H588-", - "G589-", - "A590-", - "K591-", - "I592-", - "I593-", - "H594-", - "R595-", - "Y596-", - "A597-", - "N598-", - "N599-", - "P600-", - "E601-", - "L602-", - "R603-", - "A604-", - "Y605-", - "Y606-", - "E607-", - "S608-", - "K609-", - "Q610-", - "N611-", - "K612-", - "I613-", - "Y614-", - "V615-", - "E616-", - "A617-", - "Y618-", - "D619-", - "I620-", - "I621-", - "S622-", - "D623-", - "A624-", - "I625-", - "V626-", - "K627-", - "H628-", - "N629-", - "K630-", - "I631-", - "H632-", - "K633-", - "T634-", - "I635-", - "I636-", - "K637-", - "S638-", - "V639-", - "D640-", - "D641-", - "N642-", - "T643-", - "Y644-", - "I645-", - "S646-", - "N647-", - "L648-", - "P649-", - "Y650-", - "T651-", - "I652-", - "K653-", - "Y654-", - "K655-", - "I656-", - "F657-", - "E658-", - "Q659-", - "Q660-", - "*661-" - ], - "OPG057": [ - "E353K" - ], - "OPG210": [ - "N1301X", - "R1302-", - "M1303-", - "F1304-", - "A1305-", - "T1306-", - "L1307-", - "A1308-", - "R1309-", - "G1310-", - "M1311-", - "P1312-", - "F1313-", - "R1314-", - "S1315-", - "T1316-", - "Y1317-", - "C1318-", - "D1319-", - "N1320-", - "R1321-", - "R1322-", - "R1323-", - "S1324-", - "G1325-", - "C1326-", - "Y1327-", - "Y1328-", - "A1329-", - "G1330-", - "I1331-", - "P1332-", - "F1333-", - "H1334-", - "E1335-", - "D1336-", - "S1337-", - "V1338-", - "E1339-", - "T1340-", - "D1341-", - "I1342-", - "H1343-", - "Y1344-", - "G1345-", - "P1346-", - "E1347-", - "I1348-", - "M1349-", - "L1350-", - "K1351-", - "E1352-", - "T1353-", - "Y1354-", - "D1355-", - "I1356-", - "N1357-", - "S1358-", - "I1359-", - "D1360-", - "P1361-", - "R1362-", - "V1363-", - "I1364-", - "T1365-", - "K1366-", - "S1367-", - "K1368-", - "T1369-", - "H1370-", - "F1371-", - "P1372-", - "A1373-", - "P1374-", - "L1375-", - "S1376-", - "V1377-", - "K1378-", - "F1379-", - "M1380-", - "V1381-", - "D1382-", - "N1383-", - "L1384-", - "G1385-", - "N1386-", - "G1387-", - "Y1388-", - "D1389-", - "N1390-", - "P1391-", - "N1392-", - "S1393-", - "F1394-", - "W1395-", - "E1396-", - "D1397-", - "A1398-", - "K1399-", - "T1400-", - "K1401-", - "K1402-", - "R1403-", - "T1404-", - "Y1405-", - "S1406-", - "A1407-", - "M1408-", - "T1409-", - "I1410-", - "K1411-", - "V1412-", - "L1413-", - "P1414-", - "C1415-", - "T1416-", - "V1417-", - "R1418-", - "N1419-", - "K1420-", - "N1421-", - "I1422-", - "D1423-", - "F1424-", - "G1425-", - "Y1426-", - "N1427-", - "Y1428-", - "G1429-", - "D1430-", - "I1431-", - "I1432-", - "S1433-", - "N1434-", - "M1435-", - "V1436-", - "Y1437-", - "L1438-", - "Q1439-", - "S1440-", - "T1441-", - "S1442-", - "Q1443-", - "D1444-", - "Y1445-", - "G1446-", - "D1447-", - "G1448-", - "T1449-", - "K1450-", - "Y1451-", - "T1452-", - "F1453-", - "K1454-", - "S1455-", - "V1456-", - "T1457-", - "R1458-", - "S1459-", - "D1460-", - "H1461-", - "E1462-", - "C1463-", - "E1464-", - "S1465-", - "S1466-", - "L1467-", - "D1468-", - "L1469-", - "T1470-", - "S1471-", - "K1472-", - "E1473-", - "V1474-", - "T1475-", - "V1476-", - "T1477-", - "C1478-", - "P1479-", - "A1480-", - "F1481-", - "S1482-", - "I1483-", - "P1484-", - "R1485-", - "N1486-", - "I1487-", - "S1488-", - "T1489-", - "Y1490-", - "E1491-", - "G1492-", - "L1493-", - "C1494-", - "F1495-", - "S1496-", - "V1497-", - "T1498-", - "T1499-", - "S1500-", - "K1501-", - "D1502-", - "H1503-", - "C1504-", - "A1505-", - "T1506-", - "G1507-", - "I1508-", - "G1509-", - "W1510-", - "L1511-", - "K1512-", - "S1513-", - "S1514-", - "G1515-", - "Y1516-", - "G1517-", - "K1518-", - "E1519-", - "D1520-", - "A1521-", - "D1522-", - "K1523-", - "P1524-", - "R1525-", - "A1526-", - "C1527-", - "F1528-", - "H1529-", - "H1530-", - "W1531-", - "N1532-", - "Y1533-", - "Y1534-", - "T1535-", - "L1536-", - "S1537-", - "L1538-", - "D1539-", - "Y1540-", - "Y1541-", - "C1542-", - "S1543-", - "Y1544-", - "E1545-", - "D1546-", - "I1547-", - "W1548-", - "R1549-", - "S1550-", - "T1551-", - "W1552-", - "P1553-", - "D1554-", - "Y1555-", - "D1556-", - "P1557-", - "C1558-", - "K1559-", - "S1560-", - "Y1561-", - "I1562-", - "H1563-", - "I1564-", - "E1565-", - "Y1566-", - "R1567-", - "D1568-", - "T1569-", - "W1570-", - "I1571-", - "E1572-", - "S1573-", - "N1574-", - "V1575-", - "L1576-", - "Q1577-", - "Q1578-", - "P1579-", - "P1580-", - "Y1581-", - "T1582-", - "F1583-", - "E1584-", - "F1585-", - "I1586-", - "H1587-", - "D1588-", - "N1589-", - "S1590-", - "N1591-", - "E1592-", - "Y1593-", - "V1594-", - "D1595-", - "K1596-", - "E1597-", - "I1598-", - "S1599-", - "N1600-", - "K1601-", - "L1602-", - "N1603-", - "D1604-", - "L1605-", - "Y1606-", - "N1607-", - "E1608-", - "Y1609-", - "K1610-", - "K1611-", - "I1612-", - "M1613-", - "E1614-", - "Y1615-", - "S1616-", - "D1617-", - "G1618-", - "S1619-", - "L1620-", - "P1621-", - "A1622-", - "S1623-", - "I1624-", - "N1625-", - "R1626-", - "L1627-", - "A1628-", - "K1629-", - "A1630-", - "L1631-", - "T1632-", - "S1633-", - "E1634-", - "G1635-", - "R1636-", - "E1637-", - "I1638-", - "A1639-", - "S1640-", - "V1641-", - "N1642-", - "I1643-", - "D1644-", - "G1645-", - "N1646-", - "L1647-", - "L1648-", - "D1649-", - "I1650-", - "A1651-", - "Y1652-", - "Q1653-", - "A1654-", - "D1655-", - "K1656-", - "E1657-", - "K1658-", - "M1659-", - "A1660-", - "D1661-", - "I1662-", - "Q1663-", - "T1664-", - "R1665-", - "I1666-", - "N1667-", - "D1668-", - "I1669-", - "I1670-", - "R1671-", - "D1672-", - "L1673-", - "F1674-", - "I1675-", - "H1676-", - "T1677-", - "L1678-", - "S1679-", - "D1680-", - "K1681-", - "D1682-", - "I1683-", - "K1684-", - "D1685-", - "I1686-", - "I1687-", - "E1688-", - "S1689-", - "E1690-", - "E1691-", - "G1692-", - "K1693-", - "R1694-", - "C1695-", - "C1696-", - "I1697-", - "I1698-", - "D1699-", - "V1700-", - "K1701-", - "N1702-", - "N1703-", - "L1704-", - "V1705-", - "K1706-", - "K1707-", - "Y1708-", - "Y1709-", - "S1710-", - "I1711-", - "D1712-", - "N1713-", - "Y1714-", - "L1715-", - "C1716-", - "D1717-", - "T1718-", - "L1719-", - "D1720-", - "D1721-", - "Y1722-", - "I1723-", - "Y1724-", - "T1725-", - "S1726-", - "V1727-", - "E1728-", - "Y1729-", - "N1730-", - "K1731-", - "S1732-", - "Y1733-", - "V1734-", - "L1735-", - "V1736-", - "N1737-", - "D1738-", - "T1739-", - "Y1740-", - "M1741-", - "S1742-", - "Y1743-", - "D1744-", - "Y1745-", - "L1746-", - "E1747-", - "S1748-", - "S1749-", - "G1750-", - "V1751-", - "V1752-", - "V1753-", - "L1754-", - "S1755-", - "C1756-", - "Y1757-", - "E1758-", - "M1759-", - "T1760-", - "I1761-", - "I1762-", - "S1763-", - "L1764-", - "D1765-", - "T1766-", - "K1767-", - "D1768-", - "A1769-", - "K1770-", - "D1771-", - "A1772-", - "I1773-", - "E1774-", - "D1775-", - "V1776-", - "I1777-", - "V1778-", - "A1779-", - "S1780-", - "A1781-", - "V1782-", - "A1783-", - "E1784-", - "A1785-", - "L1786-", - "N1787-", - "D1788-", - "M1789-", - "F1790-", - "K1791-", - "E1792-", - "F1793-", - "D1794-", - "K1795-", - "N1796-", - "V1797-", - "S1798-", - "A1799-", - "I1800-", - "I1801-", - "I1802-", - "K1803-", - "E1804-", - "E1805-", - "D1806-", - "N1807-", - "Y1808-", - "L1809-", - "N1810-", - "S1811-", - "S1812-", - "P1813-", - "D1814-", - "I1815-", - "Y1816-", - "H1817-", - "I1818-", - "I1819-", - "Y1820-", - "I1821-", - "I1822-", - "G1823-", - "G1824-", - "T1825-", - "I1826-", - "L1827-", - "L1828-", - "L1829-", - "L1830-", - "V1831-", - "I1832-", - "I1833-", - "L1834-", - "I1835-", - "L1836-", - "A1837-", - "I1838-", - "Y1839-", - "I1840-", - "A1841-", - "R1842-", - "N1843-", - "K1844-", - "Y1845-", - "R1846-", - "T1847-", - "R1848-", - "K1849-", - "Y1850-", - "E1851-", - "I1852-", - "M1853-", - "K1854-", - "Y1855-", - "D1856-", - "N1857-", - "M1858-", - "S1859-", - "I1860-", - "K1861-", - "S1862-", - "E1863-", - "H1864-", - "H1865-", - "D1866-", - "S1867-", - "L1868-", - "E1869-", - "T1870-", - "V1871-", - "S1872-", - "M1873-", - "E1874-", - "I1875-", - "I1876-", - "D1877-", - "N1878-", - "R1879-", - "Y1880-", - "*1881-" - ] - }, - "labels": { - "aa": "OPG015: M1-, E2-, S3-, V4-, D5-, F6-, M7-, A8-, V9-, D10-, E11-, Q12-, F13-, H14-, D15-, D16-, L17-, D18-, L19-, W20-, S21-, L22-, S23-, L24-, V25-, D26-, D27-, Y28-, K29-, K30-, H31-, G32-, L33-, G34-, V35-, D36-, C37-, Y38-, V39-, L40-, E41-, P42-, V43-, V44-, D45-, R46-, K47-, I48-, F49-, D50-, R51-, F52-, L53-, L54-, E55-, P56-, I57-, C58-, D59-, P60-, V61-, D62-, V63-, L64-, Y65-, D66-, Y67-, F68-, R69-, I70-, H71-, R72-, D73-, N74-, I75-, D76-, Q77-, Y78-, I79-, V80-, D81-, R82-, L83-, F84-, A85-, Y86-, I87-, T88-, Y89-, K90-, D91-, I92-, I93-, S94-, A95-, L96-, V97-, S98-, K99-, N100-, Y101-, M102-, E103-, D104-, I105-, F106-, S107-, I108-, I109-, I110-, K111-, N112-, C113-, N114-, S115-, V116-, Q117-, D118-, L119-, L120-, L121-, Y122-, Y123-, L124-, S125-, N126-, A127-, Y128-, V129-, E130-, I131-, D132-, I133-, V134-, D135-, L136-, M137-, V138-, D139-, H140-, G141-, A142-, V143-, I144-, Y145-, K146-, I147-, E148-, C149-, L150-, N151-, A152-, Y153-, F154-, R155-, G156-, I157-, C158-, K159-, K160-, E161-, S162-, S163-, V164-, V165-, E166-, F167-, I168-, L169-, N170-, C171-, G172-, I173-, P174-, D175-, E176-, N177-, D178-, V179-, K180-, L181-, D182-, L183-, Y184-, K185-, I186-, I187-, Q188-, Y189-, T190-, R191-, G192-, F193-, L194-, V195-, D196-, E197-, P198-, T199-, V200-, L201-, E202-, I203-, Y204-, K205-, L206-, C207-, I208-, P209-, Y210-, I211-, E212-, D213-, I214-, N215-, Q216-, L217-, D218-, A219-, G220-, G221-, R222-, T223-, L224-, L225-, Y226-, R227-, A228-, I229-, Y230-, A231-, G232-, Y233-, I234-, D235-, L236-, V237-, S238-, W239-, L240-, L241-, E242-, N243-, G244-, A245-, N246-, V247-, N248-, A249-, V250-, M251-, S252-, N253-, G254-, Y255-, T256-, C257-, L258-, D259-, V260-, A261-, V262-, D263-, R264-, G265-, S266-, V267-, I268-, A269-, R270-, R271-, E272-, A273-, H274-, L275-, K276-, I277-, L278-, E279-, I280-, L281-, L282-, R283-, E284-, P285-, L286-, S287-, I288-, D289-, C290-, I291-, K292-, L293-, A294-, I295-, L296-, N297-, N298-, T299-, I300-, E301-, N302-, H303-, D304-, V305-, I306-, K307-, L308-, C309-, I310-, K311-, Y312-, F313-, M314-, M315-, V316-, D317-, Y318-, S319-, L320-, C321-, N322-, V323-, Y324-, A325-, S326-, S327-, L328-, F329-, D330-, Y331-, I332-, I333-, D334-, C335-, K336-, Q337-, E338-, L339-, E340-, Y341-, I342-, R343-, Q344-, M345-, K346-, I347-, H348-, N349-, T350-, T351-, M352-, Y353-, E354-, L355-, I356-, Y357-, N358-, R359-, D360-, K361-, N362-, K363-, H364-, A365-, S366-, H367-, I368-, L369-, H370-, R371-, Y372-, S373-, K374-, H375-, P376-, V377-, L378-, T379-, Q380-, C381-, I382-, T383-, K384-, G385-, F386-, K387-, I388-, Y389-, T390-, E391-, V392-, T393-, E394-, Q395-, V396-, T397-, K398-, A399-, L400-, N401-, R402-, R403-, A404-, L405-, I406-, D407-, E408-, I409-, I410-, N411-, N412-, V413-, S414-, T415-, D416-, D417-, N418-, L419-, L420-, S421-, K422-, L423-, P424-, L425-, E426-, I427-, R428-, D429-, L430-, I431-, V432-, S433-, Q434-, A435-, V436-, I437-, *438-; OPG019: M1-, S2-, I3-, K4-, Y5-, L6-, M7-, L8-, L9-, F10-, A11-, A12-, M13-, I14-, I15-, R16-, S17-, L18-, A19-, D20-, S21-, G22-, N23-, A24-, I25-, E26-, T27-, T28-, S29-, P30-, E31-, I32-, T33-, N34-, A35-, T36-, T37-, D38-, I39-, P40-, A41-, I42-, R43-, L44-, C45-, G46-, P47-, E48-, G49-, D50-, G51-, Y52-, C53-, L54-, H55-, G56-, D57-, C58-, I59-, H60-, A61-, R62-, D63-, I64-, D65-, G66-, M67-, Y68-, C69-, R70-, C71-, S72-, H73-, G74-, Y75-, T76-, G77-, I78-, R79-, C80-, Q81-, H82-, V83-, V84-, L85-, V86-, D87-, Y88-, Q89-, R90-, S91-, G92-, K93-, P94-, D95-, T96-, T97-, T98-, S99-, Y100-, I101-, P102-, S103-, L104-, G105-, I106-, V107-, L108-, V109-, L110-, V111-, G112-, I113-, I114-, I115-, T116-, C117-, C118-, L119-, L120-, S121-, V122-, Y123-, M124-, F125-, T126-, R127-, R128-, T129-, K130-, L131-, P132-, I133-, Q134-, D135-, M136-, V137-, V138-, L139-, Y140-, F141-, L142-, *143-; OPG021: M1-, E2-, F3-, D4-, P5-, V6-, K7-, I8-, N9-, T10-, S11-, S12-, I13-, D14-, H15-, V16-, T17-, I18-, L19-, Q20-, Y21-, I22-, D23-, E24-, P25-, N26-, D27-, I28-, R29-, L30-, T31-, V32-, C33-, I34-, I35-, R36-, N37-, V38-, N39-, N40-, I41-, T42-, Y43-, Y44-, I45-, N46-, I47-, T48-, K49-, I50-, N51-, P52-, H53-, L54-, A55-, N56-, R57-, F58-, R59-, A60-, W61-, K62-, K63-, R64-, I65-, A66-, G67-, R68-, D69-, Y70-, M71-, T72-, N73-, L74-, S75-, R76-, D77-, T78-, G79-, I80-, Q81-, Q82-, S83-, K84-, L85-, T86-, E87-, T88-, I89-, R90-, N91-, C92-, Q93-, K94-, N95-, K96-, N97-, I98-, Y99-, G100-, L101-, Y102-, I103-, H104-, Y105-, N106-, L107-, V108-, I109-, N110-, V111-, V112-, I113-, D114-, W115-, I116-, T117-, D118-, V119-, I120-, V121-, Q122-, S123-, I124-, L125-, R126-, G127-, L128-, V129-, N130-, W131-, Y132-, I133-, A134-, N135-, N136-, T137-, Y138-, T139-, P140-, N141-, T142-, P143-, N144-, N145-, T146-, T147-, T148-, I149-, S150-, E151-, L152-, D153-, I154-, I155-, K156-, I157-, L158-, D159-, K160-, Y161-, E162-, D163-, M164-, Y165-, R166-, V167-, S168-, K169-, E170-, K171-, E172-, C173-, G174-, I175-, C176-, Y177-, E178-, V179-, V180-, Y181-, S182-, K183-, R184-, L185-, E186-, N187-, D188-, R189-, Y190-, F191-, G192-, L193-, L194-, D195-, S196-, C197-, N198-, H199-, I200-, F201-, C202-, I203-, T204-, C205-, I206-, N207-, I208-, W209-, H210-, R211-, T212-, R213-, R214-, E215-, T216-, G217-, A218-, S219-, D220-, N221-, C222-, P223-, I224-, C225-, R226-, T227-, R228-, F229-, K230-, K231-, I232-, T233-, M234-, S235-, K236-, F237-, Y238-, K239-, L240-, V241-, N242-, *243-; OPG022: M1-, R2-, I3-, L4-, F5-, L6-, I7-, A8-, F9-, M10-, Y11-, G12-, C13-, V14-, H15-, S16-, Y17-, V18-, N19-, A20-, V21-, E22-, T23-, K24-, C25-, P26-, N27-, L28-, A29-, I30-, V31-, T32-, S33-, S34-, G35-, E36-, F37-, H38-, C39-, S40-, G41-, C42-, V43-, E44-, R45-, M46-, P47-, G48-, F49-, S50-, Y51-, M52-, Y53-, W54-, L55-, A56-, N57-, D58-, M59-, K60-, S61-, D62-, E63-, D64-, T65-, K66-, F67-, I68-, E69-, H70-, L71-, G72-, G73-, G74-, I75-, K76-, E77-, D78-, E79-, T80-, V81-, R82-, T83-, T84-, D85-, G86-, G87-, I88-, T89-, T90-, L91-, R92-, K93-, V94-, L95-, H96-, V97-, T98-, D99-, T100-, N101-, K102-, F103-, A104-, H105-, Y106-, R107-, F108-, T109-, C110-, V111-, L112-, I113-, T114-, L115-, D116-, G117-, V118-, S119-, K120-, K121-, N122-, I123-, W124-, L125-, K126-, *127-; OPG023: D392N, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-, N526-, A527-, Y528-, A529-, I530-, K531-, Q532-, C533-, I534-, K535-, Y536-, T537-, M538-, I539-, I540-, D541-, D542-, C543-, T544-, S545-, S546-, K547-, I548-, P549-, E550-, S551-, I552-, S553-, Q554-, R555-, Y556-, N557-, D558-, Y559-, I560-, D561-, L562-, C563-, N564-, Q565-, E566-, L567-, N568-, E569-, M570-, K571-, K572-, I573-, M574-, V575-, G576-, G577-, N578-, T579-, M580-, F581-, S582-, L583-, I584-, F585-, T586-, E587-, H588-, G589-, A590-, K591-, I592-, I593-, H594-, R595-, Y596-, A597-, N598-, N599-, P600-, E601-, L602-, R603-, A604-, Y605-, Y606-, E607-, S608-, K609-, Q610-, N611-, K612-, I613-, Y614-, V615-, E616-, A617-, Y618-, D619-, I620-, I621-, S622-, D623-, A624-, I625-, V626-, K627-, H628-, N629-, K630-, I631-, H632-, K633-, T634-, I635-, I636-, K637-, S638-, V639-, D640-, D641-, N642-, T643-, Y644-, I645-, S646-, N647-, L648-, P649-, Y650-, T651-, I652-, K653-, Y654-, K655-, I656-, F657-, E658-, Q659-, Q660-, *661-; OPG057: E353K; OPG210: N1301X, R1302-, M1303-, F1304-, A1305-, T1306-, L1307-, A1308-, R1309-, G1310-, M1311-, P1312-, F1313-, R1314-, S1315-, T1316-, Y1317-, C1318-, D1319-, N1320-, R1321-, R1322-, R1323-, S1324-, G1325-, C1326-, Y1327-, Y1328-, A1329-, G1330-, I1331-, P1332-, F1333-, H1334-, E1335-, D1336-, S1337-, V1338-, E1339-, T1340-, D1341-, I1342-, H1343-, Y1344-, G1345-, P1346-, E1347-, I1348-, M1349-, L1350-, K1351-, E1352-, T1353-, Y1354-, D1355-, I1356-, N1357-, S1358-, I1359-, D1360-, P1361-, R1362-, V1363-, I1364-, T1365-, K1366-, S1367-, K1368-, T1369-, H1370-, F1371-, P1372-, A1373-, P1374-, L1375-, S1376-, V1377-, K1378-, F1379-, M1380-, V1381-, D1382-, N1383-, L1384-, G1385-, N1386-, G1387-, Y1388-, D1389-, N1390-, P1391-, N1392-, S1393-, F1394-, W1395-, E1396-, D1397-, A1398-, K1399-, T1400-, K1401-, K1402-, R1403-, T1404-, Y1405-, S1406-, A1407-, M1408-, T1409-, I1410-, K1411-, V1412-, L1413-, P1414-, C1415-, T1416-, V1417-, R1418-, N1419-, K1420-, N1421-, I1422-, D1423-, F1424-, G1425-, Y1426-, N1427-, Y1428-, G1429-, D1430-, I1431-, I1432-, S1433-, N1434-, M1435-, V1436-, Y1437-, L1438-, Q1439-, S1440-, T1441-, S1442-, Q1443-, D1444-, Y1445-, G1446-, D1447-, G1448-, T1449-, K1450-, Y1451-, T1452-, F1453-, K1454-, S1455-, V1456-, T1457-, R1458-, S1459-, D1460-, H1461-, E1462-, C1463-, E1464-, S1465-, S1466-, L1467-, D1468-, L1469-, T1470-, S1471-, K1472-, E1473-, V1474-, T1475-, V1476-, T1477-, C1478-, P1479-, A1480-, F1481-, S1482-, I1483-, P1484-, R1485-, N1486-, I1487-, S1488-, T1489-, Y1490-, E1491-, G1492-, L1493-, C1494-, F1495-, S1496-, V1497-, T1498-, T1499-, S1500-, K1501-, D1502-, H1503-, C1504-, A1505-, T1506-, G1507-, I1508-, G1509-, W1510-, L1511-, K1512-, S1513-, S1514-, G1515-, Y1516-, G1517-, K1518-, E1519-, D1520-, A1521-, D1522-, K1523-, P1524-, R1525-, A1526-, C1527-, F1528-, H1529-, H1530-, W1531-, N1532-, Y1533-, Y1534-, T1535-, L1536-, S1537-, L1538-, D1539-, Y1540-, Y1541-, C1542-, S1543-, Y1544-, E1545-, D1546-, I1547-, W1548-, R1549-, S1550-, T1551-, W1552-, P1553-, D1554-, Y1555-, D1556-, P1557-, C1558-, K1559-, S1560-, Y1561-, I1562-, H1563-, I1564-, E1565-, Y1566-, R1567-, D1568-, T1569-, W1570-, I1571-, E1572-, S1573-, N1574-, V1575-, L1576-, Q1577-, Q1578-, P1579-, P1580-, Y1581-, T1582-, F1583-, E1584-, F1585-, I1586-, H1587-, D1588-, N1589-, S1590-, N1591-, E1592-, Y1593-, V1594-, D1595-, K1596-, E1597-, I1598-, S1599-, N1600-, K1601-, L1602-, N1603-, D1604-, L1605-, Y1606-, N1607-, E1608-, Y1609-, K1610-, K1611-, I1612-, M1613-, E1614-, Y1615-, S1616-, D1617-, G1618-, S1619-, L1620-, P1621-, A1622-, S1623-, I1624-, N1625-, R1626-, L1627-, A1628-, K1629-, A1630-, L1631-, T1632-, S1633-, E1634-, G1635-, R1636-, E1637-, I1638-, A1639-, S1640-, V1641-, N1642-, I1643-, D1644-, G1645-, N1646-, L1647-, L1648-, D1649-, I1650-, A1651-, Y1652-, Q1653-, A1654-, D1655-, K1656-, E1657-, K1658-, M1659-, A1660-, D1661-, I1662-, Q1663-, T1664-, R1665-, I1666-, N1667-, D1668-, I1669-, I1670-, R1671-, D1672-, L1673-, F1674-, I1675-, H1676-, T1677-, L1678-, S1679-, D1680-, K1681-, D1682-, I1683-, K1684-, D1685-, I1686-, I1687-, E1688-, S1689-, E1690-, E1691-, G1692-, K1693-, R1694-, C1695-, C1696-, I1697-, I1698-, D1699-, V1700-, K1701-, N1702-, N1703-, L1704-, V1705-, K1706-, K1707-, Y1708-, Y1709-, S1710-, I1711-, D1712-, N1713-, Y1714-, L1715-, C1716-, D1717-, T1718-, L1719-, D1720-, D1721-, Y1722-, I1723-, Y1724-, T1725-, S1726-, V1727-, E1728-, Y1729-, N1730-, K1731-, S1732-, Y1733-, V1734-, L1735-, V1736-, N1737-, D1738-, T1739-, Y1740-, M1741-, S1742-, Y1743-, D1744-, Y1745-, L1746-, E1747-, S1748-, S1749-, G1750-, V1751-, V1752-, V1753-, L1754-, S1755-, C1756-, Y1757-, E1758-, M1759-, T1760-, I1761-, I1762-, S1763-, L1764-, D1765-, T1766-, K1767-, D1768-, A1769-, K1770-, D1771-, A1772-, I1773-, E1774-, D1775-, V1776-, I1777-, V1778-, A1779-, S1780-, A1781-, V1782-, A1783-, E1784-, A1785-, L1786-, N1787-, D1788-, M1789-, F1790-, K1791-, E1792-, F1793-, D1794-, K1795-, N1796-, V1797-, S1798-, A1799-, I1800-, I1801-, I1802-, K1803-, E1804-, E1805-, D1806-, N1807-, Y1808-, L1809-, N1810-, S1811-, S1812-, P1813-, D1814-, I1815-, Y1816-, H1817-, I1818-, I1819-, Y1820-, I1821-, I1822-, G1823-, G1824-, T1825-, I1826-, L1827-, L1828-, L1829-, L1830-, V1831-, I1832-, I1833-, L1834-, I1835-, L1836-, A1837-, I1838-, Y1839-, I1840-, A1841-, R1842-, N1843-, K1844-, Y1845-, R1846-, T1847-, R1848-, K1849-, Y1850-, E1851-, I1852-, M1853-, K1854-, Y1855-, D1856-, N1857-, M1858-, S1859-, I1860-, K1861-, S1862-, E1863-, H1864-, H1865-, D1866-, S1867-, L1868-, E1869-, T1870-, V1871-, S1872-, M1873-, E1874-, I1875-, I1876-, D1877-, N1878-, R1879-, Y1880-, *1881-" - } - } - }, - { - "name": "MPXV/003/19", - "node_attrs": { - "div": 23, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2019-01-16" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/003/19" - }, - "strain": { - "value": "OP612674" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C11555T", - "G28645A", - "G75967A", - "T76079-", - "G94840A", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "C188503T", - "A196603-", - "A196604-", - "A196605-", - "A196606-" - ], - "OPG023": [ - "R449Q" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG115": [ - "E61K" - ] - }, - "labels": { - "aa": "OPG023: R449Q; OPG097: K266X, *345X; OPG115: E61K" - } - } - }, - { - "name": "NODE_0000030", - "node_attrs": { - "div": 19, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G1126A", - "G2039A", - "T76079-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "A173300-", - "T173301-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "C195171T", - "C196084T" - ], - "OPG002": [ - "S238L" - ], - "OPG097": [ - "K266X", - "*345X" - ] - }, - "labels": { - "aa": "OPG002: S238L; OPG097: K266X, *345X" - } - }, - "children": [ - { - "name": "MPXV/040/19", - "node_attrs": { - "div": 22, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2019-04-29" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/040/19" - }, - "strain": { - "value": "OP612682" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C69017T", - "C150406T", - "G182196A", - "-196601A", - "-196602A" - ], - "OPG087": [ - "S54F" - ], - "OPG210": [ - "D281N" - ] - }, - "labels": { - "aa": "OPG087: S54F; OPG210: D281N" - } - } - }, - { - "name": "MPXV/104/19", - "node_attrs": { - "div": 28, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2019-11-16" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/104/19" - }, - "strain": { - "value": "OP612688" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "G2152A", - "C6948T", - "C47224T", - "C77726T", - "C143845T", - "G152431A", - "C166786T", - "G184037T", - "C184535T", - "C195058T" - ], - "OPG066": [ - "E69K" - ], - "OPG099": [ - "S21F" - ], - "OPG192": [ - "S19L" - ] - }, - "labels": { - "aa": "OPG066: E69K; OPG099: S21F; OPG192: S19L" - } - } - } - ] - }, - { - "name": "NODE_0000031", - "node_attrs": { - "div": 19, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T146862-", - "A146863-", - "T146864-", - "T146865-", - "T146866-", - "T146867-", - "A146868-", - "T146869-", - "A146870-", - "T146871-", - "T146872-", - "T146873-", - "T146874-", - "A146875-", - "T146876-", - "A146877-", - "T146878-", - "T146879-", - "T146880-", - "G151929A", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "A173300-", - "T173301-", - "-196601A", - "-196602A" - ], - "OPG178": [ - "E141K" - ] - }, - "labels": { - "aa": "OPG178: E141K" - } - }, - "children": [ - { - "name": "MPXV/042/19", - "node_attrs": { - "div": 21, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2019-04-29" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/042/19" - }, - "strain": { - "value": "OP612683" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "T76079-", - "G81523A", - "C141757T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG105": [ - "S133N" - ] - }, - "labels": { - "aa": "OPG097: K266X, *345X; OPG105: S133N" - } - } - }, - { - "name": "NODE_0000032", - "node_attrs": { - "div": 20, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C39767T" - ] - } - }, - "children": [ - { - "name": "MPXV-Singapore", - "node_attrs": { - "div": 22, - "author": { - "author": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y.", - "value": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y." - }, - "country": { - "value": "Singapore" - }, - "date": { - "value": "2019-05-XX" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV-Singapore" - }, - "strain": { - "value": "MT903342" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "C43927T", - "-146862T", - "-146863A", - "-146864T", - "-146865T", - "-146866T", - "-146867T", - "-146868A", - "-146869T", - "-146870A", - "-146871T", - "-146872T", - "-146873T", - "-146874T", - "-146875A", - "-146876T", - "-146877A", - "-146878T", - "-146879T", - "-146880T", - "C170573T", - "-173274A", - "-173275T", - "-173276A", - "-173277T", - "-173278A", - "-173279T", - "-173280A", - "-173281T", - "-173282A", - "-173283T", - "-173284A", - "-173285T", - "-173286A", - "-173287T", - "-173288A", - "-173289T", - "-173290A", - "-173291T", - "-173292A", - "-173293T", - "-173294A", - "-173295T", - "-173296A", - "-173297T", - "-173298A", - "-173299T", - "-173300A", - "-173301T", - "A196601-" - ], - "OPG064": [ - "E658K" - ], - "OPG198": [ - "S179L" - ] - }, - "labels": { - "aa": "OPG064: E658K; OPG198: S179L" - } - } - }, - { - "name": "MPXV/052/19", - "node_attrs": { - "div": 20, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2019-06-08" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/052/19" - }, - "strain": { - "value": "OP612685" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T595-", - "T596-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T" - ] - } - } - } - ] - }, - { - "name": "NODE_0000033", - "node_attrs": { - "div": 26, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C13065T", - "C29887T", - "G61329A", - "C72206T", - "G103431A", - "-146862T", - "-146863A", - "-146864T", - "-146865T", - "-146866T", - "-146867T", - "-146868A", - "-146869T", - "-146870A", - "-146871T", - "-146872T", - "-146873T", - "-146874T", - "-146875A", - "-146876T", - "-146877A", - "-146878T", - "-146879T", - "-146880T", - "C165369T", - "-173296A", - "-173297T", - "-173298A", - "-173299T", - "-173300A", - "-173301T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "G188949A", - "T192184C" - ], - "OPG024": [ - "G55E" - ], - "OPG092": [ - "E248K" - ], - "OPG123": [ - "S547L" - ], - "OPG190": [ - "S83F" - ] - }, - "labels": { - "aa": "OPG024: G55E; OPG092: E248K; OPG123: S547L; OPG190: S83F" - } - }, - "children": [ - { - "name": "2091", - "node_attrs": { - "div": 26, - "author": { - "author": "Atkinson,B., Pottage,T., Ngabo,D., Crook,A., Pitman,J., Summers,S., Pullan,S., Lewandowski,K., Furneaux,J., Davies,K., Brooks,T.", - "value": "Atkinson,B., Pottage,T., Ngabo,D., Crook,A., Pitman,J., Summers,S., Pullan,S., Lewandowski,K., Furneaux,J., Davies,K., Brooks,T." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2019-12-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "2091" - }, - "strain": { - "value": "OL504741" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T192413C" - ] - } - } - }, - { - "name": "2095", - "node_attrs": { - "div": 26, - "author": { - "author": "Atkinson,B., Pottage,T., Ngabo,D., Crook,A., Pitman,J., Summers,S., Pullan,S., Lewandowski,K., Furneaux,J., Davies,K., Brooks,T.", - "value": "Atkinson,B., Pottage,T., Ngabo,D., Crook,A., Pitman,J., Summers,S., Pullan,S., Lewandowski,K., Furneaux,J., Davies,K., Brooks,T." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2019-12-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "2095" - }, - "strain": { - "value": "OL504742" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000034", - "node_attrs": { - "div": 20, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G25661A", - "C39119T", - "-173274A", - "-173275T", - "-173276A", - "-173277T" - ] - } - }, - "children": [ - { - "name": "MPXV/018/19", - "node_attrs": { - "div": 28, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2019-03-18" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/018/19" - }, - "strain": { - "value": "OP612679" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C8500T", - "G79538A", - "G81354A", - "G84416A", - "C88736T", - "G100642A", - "C138791T", - "C161616T" - ], - "OPG102": [ - "D152N" - ], - "OPG105": [ - "E77K" - ], - "OPG109": [ - "E238K" - ], - "OPG119": [ - "R86K" - ], - "OPG156": [ - "D207N" - ] - }, - "labels": { - "aa": "OPG102: D152N; OPG105: E77K; OPG109: E238K; OPG119: R86K; OPG156: D207N" - } - } - }, - { - "name": "NODE_0000035", - "node_attrs": { - "div": 21, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T595-", - "G162243A", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A196603-" - ] - } - }, - "children": [ - { - "name": "MPXV-UK_P2", - "node_attrs": { - "div": 21, - "author": { - "author": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y.", - "value": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2018-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV-UK_P2" - }, - "strain": { - "value": "MT903344" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-196603A" - ] - } - } - }, - { - "name": "MPXV-UK_P3", - "node_attrs": { - "div": 21, - "author": { - "author": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y.", - "value": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2018-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV-UK_P3" - }, - "strain": { - "value": "MT903345" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-" - ] - } - } - }, - { - "name": "NODE_0000036", - "node_attrs": { - "div": 24, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G1262A", - "C3818T", - "G124130A", - "C128698T", - "T133078-", - "C133164-", - "A133165-", - "A133166-", - "T133167-", - "C133168-", - "T133169-", - "T133170-", - "T133171-", - "C133172-", - "T133173-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "A173300-", - "T173301-", - "G193392A", - "C195948T" - ], - "OPG001": [ - "S105L" - ], - "OPG003": [ - "D264N" - ], - "OPG145": [ - "E62K" - ], - "OPG150": [ - "S307L" - ] - }, - "labels": { - "aa": "OPG001: S105L; OPG003: D264N; OPG145: E62K; OPG150: S307L" - } - }, - "children": [ - { - "name": "MPXV/058/19", - "node_attrs": { - "div": 29, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2019-08-19" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/058/19" - }, - "strain": { - "value": "OP612687" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "T597-", - "C756T", - "G2039A", - "G168365A", - "A173302-", - "T173303-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "C188605A", - "A188606C", - "G188607A", - "T193455A", - "C195171T", - "G196454-", - "A196604-" - ], - "OPG002": [ - "S238L" - ], - "OPG003": [ - "L285I" - ], - "OPG195": [ - "E46K" - ] - }, - "labels": { - "aa": "OPG002: S238L; OPG003: L285I; OPG195: E46K" - } - } - }, - { - "name": "NODE_0000037", - "node_attrs": { - "div": 25, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G81275A" - ] - } - }, - "children": [ - { - "name": "MPXV/053/19", - "node_attrs": { - "div": 26, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "country": { - "value": "Nigeria" - }, - "date": { - "value": "2019-07-01" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/053/19" - }, - "strain": { - "value": "OP612686" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "T76079-", - "G88640A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196601A", - "-196602A", - "-196603A" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG109": [ - "R270C" - ] - }, - "labels": { - "aa": "OPG097: K266X, *345X; OPG109: R270C" - } - } - }, - { - "name": "NODE_0000038", - "node_attrs": { - "div": 50, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "A.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G2591A", - "G3522A", - "C7771T", - "G14000T", - "G15428A", - "G21723A", - "G30367A", - "G31053A", - "G34459A", - "G37202A", - "G38360A", - "C38662T", - "G52885A", - "G54117A", - "G54635A", - "G64297A", - "C73066T", - "C82373T", - "G82451A", - "G95034A", - "G124674A", - "-133078T", - "C162331T", - "-173274A", - "-173275T", - "-173276A", - "-173277T", - "-173278A", - "-173279T", - "-173280A", - "-173281T", - "-173282A", - "-173283T", - "-173284A", - "-173285T", - "-173286A", - "-173287T", - "-173288A", - "-173289T", - "-173290A", - "-173291T", - "-173292A", - "-173293T", - "-173294A", - "-173295T", - "-173296A", - "-173297T", - "-173298A", - "-173299T", - "-173300A", - "-173301T", - "G178133A", - "G181980A", - "G186578A", - "C193688T", - "C194619T" - ], - "OPG002": [ - "S54F" - ], - "OPG025": [ - "A423D" - ], - "OPG047": [ - "R48C" - ], - "OPG053": [ - "P78S" - ], - "OPG056": [ - "E125K" - ], - "OPG071": [ - "L108F" - ], - "OPG072": [ - "D56N" - ], - "OPG093": [ - "S30L" - ], - "OPG145": [ - "R243Q" - ], - "OPG210": [ - "D209N", - "M1741I" - ] - }, - "labels": { - "aa": "OPG002: S54F; OPG025: A423D; OPG047: R48C; OPG053: P78S; OPG056: E125K; OPG071: L108F; OPG072: D56N; OPG093: S30L; OPG145: R243Q; OPG210: D209N, M1741I", - "clade": "A.1.1" - } - }, - "children": [ - { - "name": "MPXV_USA_2021_MD", - "node_attrs": { - "div": 53, - "author": { - "author": "Gigante,C.M., Myers,R., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Blythe,D., Li,Y.", - "value": "Gigante,C.M., Myers,R., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Blythe,D., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2021-11-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2021_MD" - }, - "strain": { - "value": "ON676708" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "A.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C79348T", - "C86979T", - "C133714T", - "C169722-", - "A169723-", - "G169724-", - "A169725-", - "T169726-", - "A169727-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-" - ], - "OPG197": [ - "S18X", - "D19-", - "T20X", - "*101X" - ] - }, - "labels": { - "aa": "OPG197: S18X, D19-, T20X, *101X" - } - } - }, - { - "name": "NODE_0000039", - "node_attrs": { - "div": 61, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G3111A", - "C39139T", - "G73239A", - "G74205A", - "G77383A", - "C84587T", - "C150469T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "A151461C", - "G155795A", - "G170262A", - "C183519T", - "C194099T" - ], - "OPG057": [ - "E353K" - ], - "OPG093": [ - "D88N" - ], - "OPG094": [ - "M142I" - ], - "OPG098": [ - "E162K" - ], - "OPG176": [ - "H221Y" - ], - "OPG210": [ - "P722S" - ] - }, - "labels": { - "aa": "OPG057: E353K; OPG093: D88N; OPG094: M142I; OPG098: E162K; OPG176: H221Y; OPG210: P722S", - "clade": "B.1" - } - }, - "children": [ - { - "name": "MPXV/human/Japan/Tokyo/TKY220091/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "country": { - "value": "Japan" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/TKY220091/2022" - }, - "strain": { - "value": "LC722946" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C13653T", - "C116100T", - "G150376A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG025": [ - "D539N" - ], - "OPG176": [ - "D190N" - ] - }, - "labels": { - "aa": "OPG025: D539N; OPG176: D190N" - } - } - }, - { - "name": "MPXV-CH-38134631/2022", - "node_attrs": { - "div": 61, - "author": { - "author": "Laubscher,F., Chudzinski,V., Schibler,M., Kaiser,L., Renzoni,A.", - "value": "Laubscher,F., Chudzinski,V., Schibler,M., Kaiser,L., Renzoni,A." - }, - "country": { - "value": "Switzerland" - }, - "date": { - "value": "2022-05-19" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Laboratory of Viorology, University Hospital of Geneva, Switzerland" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV-CH-38134631/2022" - }, - "strain": { - "value": "ON595760" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "T597-", - "T133078-", - "T133079-", - "G179056-", - "T179057-", - "T179058-", - "T179059-", - "A179060-", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-", - "A196604-" - ] - } - } - }, - { - "name": "MPXV_2022_NL001", - "node_attrs": { - "div": 63, - "author": { - "author": "Oude Munnink,B.B., Boter,M., Wellers,B., Molenkamp,R., Sikkema,R.S., Koopmans,M.", - "value": "Oude Munnink,B.B., Boter,M., Wellers,B., Molenkamp,R., Sikkema,R.S., Koopmans,M." - }, - "country": { - "value": "Netherlands" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Public Health Virology, Erasmus Medical Centre, The Netherlands" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_2022_NL001" - }, - "strain": { - "value": "ON615424" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G155611A", - "G171003A", - "A178777-", - "C178778-", - "A178779-", - "C178780-", - "G178781-", - "A178782-", - "A178783-", - "T178784-", - "A178785-", - "T178786-", - "G178787-", - "T178788-", - "A178789-", - "T178790-", - "G178791-", - "A178792-", - "C178793-", - "G178794-", - "G178795-", - "A178796-", - "T178797-", - "G178798-", - "G178799-", - "G178800-", - "A178801-", - "A178802-", - "T178803-", - "T178804-", - "G178805-", - "G178806-", - "T178807-", - "A178808-", - "A178809-", - "C178810-", - "G178811-", - "A178812-", - "T178813-", - "G178814-", - "A178815-", - "C178816-", - "A178817-", - "G178818-", - "A178819-", - "A178820-", - "A178821-", - "G178822-", - "C178823-", - "A178824-", - "G178825-", - "A178826-", - "T178827-", - "T178828-", - "G178829-", - "T178830-", - "C178831-", - "A178832-", - "G178833-", - "C178834-", - "T178835-", - "C178836-", - "T178837-", - "G178838-", - "C178839-", - "A178840-", - "T178841-", - "A178842-", - "C178843-", - "T178844-", - "A178845-", - "T178846-", - "T178847-", - "C178848-", - "T178849-", - "T178850-", - "C178851-", - "A178852-", - "T178853-", - "G178854-", - "A178855-", - "C178856-", - "A178857-", - "A178858-", - "T178859-", - "A178860-", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "-196603A" - ], - "OPG199": [ - "E6K" - ] - }, - "labels": { - "aa": "OPG199: E6K" - } - } - }, - { - "name": "MPXV-CH-38156923/2022", - "node_attrs": { - "div": 61, - "author": { - "author": "Laubscher,F., Schibler,M., Kaiser,L., Renzoni,A.", - "value": "Laubscher,F., Schibler,M., Kaiser,L., Renzoni,A." - }, - "country": { - "value": "Switzerland" - }, - "date": { - "value": "2022-05-24" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Laboratory of Viorology, University Hospital of Geneva, Switzerland" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV-CH-38156923/2022" - }, - "strain": { - "value": "ON622720" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "2022/2 SLO", - "node_attrs": { - "div": 61, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "country": { - "value": "Slovenia" - }, - "date": { - "value": "2022-05-24" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "2022/2 SLO" - }, - "strain": { - "value": "ON631241" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPxV/VIDRL01/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Hammerschlag,Y., MacLeod,G., Papadakis,G., Adnan Sanchez,A., Druce,J., Savic,I., Taiaroa,G., Roberts,J., Caly,L., Williamson,D.A., Cheng,A.C., McMahon,J.H.", - "value": "Hammerschlag,Y., MacLeod,G., Papadakis,G., Adnan Sanchez,A., Druce,J., Savic,I., Taiaroa,G., Roberts,J., Caly,L., Williamson,D.A., Cheng,A.C., McMahon,J.H." - }, - "country": { - "value": "Australia" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "Oceania" - }, - "institution": { - "value": "Victorian Infectious Diseases Reference Laboratory, Doherty Institute, Australia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPxV/VIDRL01/2022" - }, - "strain": { - "value": "ON631963" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C21128T", - "C133077T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196603A" - ], - "OPG037": [ - "E436K" - ] - }, - "labels": { - "aa": "OPG037: E436K" - } - } - }, - { - "name": "MPXV_GSTT_Patient1", - "node_attrs": { - "div": 61, - "author": { - "author": "Alcolea-Medina,A., Charalampous,T., Snell,L.B., Batra,R., Edgeworth,J.D.", - "value": "Alcolea-Medina,A., Charalampous,T., Snell,L.B., Batra,R., Edgeworth,J.D." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-05-11" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Clinical Infection & Diagnostics Research, Kings College London, St Thomas Hospital, UK" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_GSTT_Patient1" - }, - "strain": { - "value": "ON645312" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "T597-", - "T598-", - "T599-", - "T600-", - "T601-", - "T602-", - "T617-", - "A2237-", - "C2238-", - "G2239-", - "C4693-", - "T4694-", - "T4695-", - "A4696-", - "A4697-", - "C4698-", - "T4699-", - "A4700-", - "A4701-", - "C4702-", - "T4703-", - "T4704-", - "A4705-", - "T4706-", - "G4707-", - "A4708-", - "C4709-", - "T4710-", - "T4711-", - "A4712-", - "A4713-", - "C4714-", - "T4715-", - "A4716-", - "A4717-", - "C4718-", - "T4719-", - "T4720-", - "A4721-", - "T4722-", - "G4723-", - "A4724-", - "C4725-", - "T4726-", - "T4727-", - "A4728-", - "A4729-", - "C4730-", - "T4731-", - "A4732-", - "A4733-", - "C4734-", - "T4735-", - "T4736-", - "A4737-", - "T4738-", - "G4739-", - "A4740-", - "C4741-", - "T4742-", - "T4743-", - "A4744-", - "A4745-", - "C4746-", - "T4747-", - "A4748-", - "A4749-", - "C4750-", - "T4751-", - "T4752-", - "A4753-", - "T4754-", - "G4755-", - "A4756-", - "C4757-", - "T4758-", - "T4759-", - "A4760-", - "A4761-", - "C4762-", - "T4763-", - "A4764-", - "A4765-", - "C4766-", - "T4767-", - "T4768-", - "A4769-", - "T4770-", - "G4771-", - "A4772-", - "C4773-", - "T4774-", - "T4775-", - "C6429-", - "T6430-", - "C7016-", - "T7017-", - "C7018-", - "T7019-", - "C7020-", - "G7021-", - "A7142-", - "T7143-", - "C7144-", - "T7145-", - "T7404-", - "A8048-", - "A8049-", - "T8325-", - "T8326-", - "A8419-", - "T8420-", - "A8421-", - "T8422-", - "A8471-", - "T8494-", - "T8913-", - "T8992-", - "A9282-", - "A9523-", - "A10274-", - "T10497-", - "A13276-", - "T13352-", - "T15546-", - "A15547-", - "A15867-", - "G16608-", - "T16609-", - "C16610-", - "A16611-", - "T16612-", - "C16613-", - "A18055-", - "C18056-", - "C18057-", - "A21075-", - "A23167-", - "A24307-", - "C24336-", - "A27108-", - "A28524-", - "A28525-", - "A28583-", - "T28584-", - "T28585-", - "A28586-", - "T28587-", - "C28588-", - "C28589-", - "A28590-", - "G28591-", - "T28592-", - "G28593-", - "T28594-", - "T28595-", - "A28596-", - "A28597-", - "A28598-", - "A28599-", - "A28600-", - "A28601-", - "T32188-", - "G32209-", - "A32210-", - "C32211-", - "A33193-", - "T33409-", - "T35565-", - "T41738-", - "T41929-", - "A43495-", - "A45117-", - "A46506-", - "C46507-", - "A46508-", - "T46590-", - "T46643-", - "A47573-", - "A47700-", - "C47701-", - "T48162-", - "A48163-", - "G48164-", - "T50499-", - "C50500-", - "T50575-", - "A50576-", - "A57274-", - "A58644-", - "A62034-", - "T62369-", - "T64749-", - "T66777-", - "A66839-", - "A71174-", - "T71896-", - "T76079-", - "T76080-", - "A76883-", - "T80841-", - "T80842-", - "A81968-", - "T87399-", - "T88831-", - "A89100-", - "A91698-", - "T94640-", - "T94641-", - "T97549-", - "T102743-", - "T103362-", - "T105355-", - "C106158-", - "C115266-", - "T116958-", - "T121116-", - "A123988-", - "A124720-", - "A127747-", - "A127748-", - "A128927-", - "G131761-", - "T132811-", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "T133084-", - "T133085-", - "T133086-", - "T133087-", - "T133088-", - "T133089-", - "T133090-", - "T133091-", - "T133092-", - "T133493-", - "C133494-", - "G133495-", - "G133496-", - "T133497-", - "C133498-", - "C133499-", - "A133500-", - "T133501-", - "G133502-", - "T133503-", - "C133504-", - "T133505-", - "C133506-", - "C133507-", - "A133508-", - "T133509-", - "T133510-", - "G133511-", - "C133512-", - "T133513-", - "A133514-", - "C133515-", - "A133516-", - "C133517-", - "C133518-", - "A133519-", - "C133520-", - "C133521-", - "A133522-", - "T133523-", - "T133524-", - "A133525-", - "G133526-", - "A133527-", - "T133528-", - "T133529-", - "T133530-", - "A133531-", - "C133532-", - "A133533-", - "G133534-", - "G133535-", - "C133536-", - "T133537-", - "G133538-", - "C133539-", - "T133540-", - "A133541-", - "G133542-", - "T133543-", - "T133544-", - "G133545-", - "T133546-", - "C133547-", - "G133548-", - "T133549-", - "T133550-", - "C133551-", - "G133552-", - "A133553-", - "G133554-", - "A133555-", - "T133556-", - "C133557-", - "A133558-", - "G133559-", - "A133560-", - "A133561-", - "A133562-", - "T133563-", - "A133564-", - "C133565-", - "G133566-", - "T133567-", - "G133568-", - "T133569-", - "T133570-", - "T133571-", - "T133572-", - "C133573-", - "T133574-", - "T133575-", - "G133576-", - "G133577-", - "A133578-", - "A133579-", - "T133580-", - "G133581-", - "G133582-", - "A133583-", - "T133584-", - "T133585-", - "T133586-", - "C133587-", - "G133588-", - "T133589-", - "C133590-", - "G133591-", - "A133592-", - "T133593-", - "G133594-", - "T133595-", - "A133596-", - "C133597-", - "T133598-", - "T133599-", - "G133600-", - "T133601-", - "C133602-", - "A133603-", - "T133604-", - "G133605-", - "A133606-", - "T133607-", - "T133608-", - "G133609-", - "G133610-", - "C133611-", - "A133612-", - "T133613-", - "C133614-", - "G133615-", - "A133616-", - "A133617-", - "A133618-", - "C133619-", - "A133620-", - "C133621-", - "T133622-", - "T133623-", - "A133624-", - "T133625-", - "T133626-", - "A133627-", - "A133628-", - "G133629-", - "T133630-", - "T133631-", - "C133632-", - "T133633-", - "T133634-", - "T133635-", - "T133636-", - "T133637-", - "T133638-", - "T133639-", - "C133640-", - "A133641-", - "A133642-", - "T133643-", - "T133644-", - "C133645-", - "T133646-", - "A133647-", - "C133648-", - "G133649-", - "A133650-", - "T133651-", - "T133652-", - "T133653-", - "T133654-", - "A133655-", - "T133656-", - "T133657-", - "T133658-", - "C133659-", - "T133660-", - "T133661-", - "T133662-", - "C133663-", - "G133664-", - "C133665-", - "G133666-", - "A133667-", - "G133668-", - "T133669-", - "C133670-", - "A133671-", - "A133672-", - "T133673-", - "T133674-", - "C133675-", - "C133676-", - "C133677-", - "T133678-", - "C133679-", - "C133680-", - "T133681-", - "G133682-", - "T133683-", - "A133684-", - "G133685-", - "T133686-", - "A133687-", - "A133688-", - "C133689-", - "T133690-", - "A133691-", - "T133692-", - "C133693-", - "A133694-", - "G133695-", - "T133696-", - "T133697-", - "T133698-", - "T133699-", - "G133700-", - "T133701-", - "C133702-", - "A133703-", - "G133704-", - "A133705-", - "T133706-", - "T133707-", - "C133708-", - "A133709-", - "C133710-", - "G133711-", - "C133712-", - "T133713-", - "C133714-", - "T133715-", - "C133716-", - "T133717-", - "A133718-", - "C133719-", - "G133720-", - "T133721-", - "A133722-", - "G133723-", - "A133724-", - "C133725-", - "T133726-", - "T133727-", - "T133728-", - "C133729-", - "T133730-", - "T133731-", - "G133732-", - "T133733-", - "A133734-", - "A133735-", - "G133736-", - "T133737-", - "T133738-", - "A133739-", - "C133740-", - "T133741-", - "A133742-", - "A133743-", - "T133744-", - "T133745-", - "T133746-", - "G133747-", - "T133748-", - "T133749-", - "C133750-", - "C133751-", - "C133752-", - "T133753-", - "G133754-", - "G133755-", - "C133756-", - "A133757-", - "T133758-", - "T133759-", - "A133760-", - "C133761-", - "C133762-", - "G133763-", - "A133764-", - "G133765-", - "T133766-", - "T133767-", - "C133768-", - "A133769-", - "G133770-", - "T133771-", - "T133772-", - "T133773-", - "T133774-", - "A133775-", - "T133776-", - "A133777-", - "T133778-", - "G133779-", - "C133780-", - "C133781-", - "G133782-", - "A133783-", - "A133784-", - "T133785-", - "A133786-", - "G133787-", - "A133788-", - "G133789-", - "T133790-", - "T133791-", - "C133792-", - "T133793-", - "G133794-", - "A133795-", - "T133796-", - "T133797-", - "C133798-", - "A133799-", - "T133800-", - "C133801-", - "C133802-", - "T133803-", - "T133804-", - "T133805-", - "G133806-", - "A133807-", - "G133808-", - "A133809-", - "A133810-", - "G133811-", - "A133812-", - "T133813-", - "C133814-", - "T133815-", - "C133816-", - "T133817-", - "A133818-", - "G133819-", - "C133820-", - "G133821-", - "A133822-", - "T133823-", - "C133824-", - "G133825-", - "T133826-", - "T133827-", - "C133828-", - "A133829-", - "A133830-", - "G133831-", - "A133832-", - "T133833-", - "C133834-", - "C133835-", - "C133836-", - "T133837-", - "G133838-", - "A133839-", - "T133840-", - "T133841-", - "C133842-", - "T133843-", - "A133844-", - "G133845-", - "T133846-", - "C133847-", - "T133848-", - "T133849-", - "T133850-", - "A133851-", - "G133852-", - "C133853-", - "C133854-", - "T133855-", - "A133856-", - "T133857-", - "T133858-", - "T133859-", - "A133860-", - "C133861-", - "C133862-", - "T133863-", - "C133864-", - "C133865-", - "T133866-", - "C133867-", - "A133868-", - "G133869-", - "A133870-", - "A133871-", - "G133872-", - "A133873-", - "T133874-", - "G133875-", - "C133876-", - "T133877-", - "C133878-", - "C133879-", - "G133880-", - "T133881-", - "T133882-", - "A133883-", - "C133884-", - "C133885-", - "G133886-", - "T133887-", - "T133888-", - "T133889-", - "T133890-", - "T133891-", - "A133892-", - "C133893-", - "A133894-", - "A133895-", - "T133896-", - "C133897-", - "G133898-", - "T133899-", - "T133900-", - "A133901-", - "A133902-", - "G133903-", - "A133904-", - "T133905-", - "G133906-", - "T133907-", - "C133908-", - "T133909-", - "A133910-", - "T133911-", - "C133912-", - "A133913-", - "A133914-", - "G133915-", - "A133916-", - "T133917-", - "C133918-", - "C133919-", - "A133920-", - "T133921-", - "G133922-", - "A133923-", - "T133924-", - "T133925-", - "C133926-", - "T133927-", - "A133928-", - "T133929-", - "C133930-", - "T133931-", - "C133932-", - "T133933-", - "T133934-", - "T133935-", - "T133936-", - "C133937-", - "C133938-", - "A133939-", - "T133940-", - "A133941-", - "T133942-", - "C133943-", - "A133944-", - "G133945-", - "T137881-", - "A138468-", - "T139424-", - "G139425-", - "T139426-", - "A140105-", - "T140106-", - "A140107-", - "A140108-", - "C140109-", - "A140110-", - "A140111-", - "T140112-", - "T140113-", - "A142752-", - "G143458-", - "A145892-", - "T145976-", - "A145977-", - "A145978-", - "C146084-", - "G146085-", - "T146127-", - "T146860-", - "A146861-", - "T146869-", - "A146870-", - "T146871-", - "T146872-", - "T146873-", - "T146874-", - "A146875-", - "T146876-", - "A146877-", - "T146878-", - "T146879-", - "T146880-", - "A146964-", - "A148136-", - "A148206-", - "T148337-", - "T150532-", - "A151015-", - "T151016-", - "G151017-", - "A151018-", - "C151019-", - "A151042-", - "T152265-", - "T152266-", - "A152267-", - "A152668-", - "A152669-", - "A153418-", - "T154351-", - "C154352-", - "T155417-", - "A156206-", - "T156370-", - "T156371-", - "A156372-", - "C156373-", - "T156374-", - "G156375-", - "A156376-", - "C156377-", - "T156378-", - "A156379-", - "C156380-", - "A156381-", - "T156382-", - "G156383-", - "T156384-", - "A156385-", - "C156386-", - "T156387-", - "A156388-", - "T156389-", - "T156390-", - "T156391-", - "T156392-", - "A156393-", - "C156394-", - "A156395-", - "T156396-", - "T156397-", - "A156398-", - "C156399-", - "T156400-", - "A156401-", - "C156402-", - "A156403-", - "T156404-", - "T156405-", - "G156406-", - "G156407-", - "C156408-", - "T156409-", - "A156410-", - "C156411-", - "G156412-", - "G156413-", - "C156414-", - "A156415-", - "T156416-", - "A156417-", - "T156418-", - "A156419-", - "T156420-", - "A156421-", - "C156422-", - "C156423-", - "T156424-", - "A156425-", - "T156426-", - "T156427-", - "T156428-", - "C156429-", - "G156430-", - "T156431-", - "C156432-", - "A156433-", - "C156434-", - "T156435-", - "T156436-", - "C156437-", - "C156438-", - "A156439-", - "C156440-", - "A156441-", - "C156442-", - "G156443-", - "C156444-", - "T156445-", - "C156446-", - "C156447-", - "G156448-", - "G156449-", - "T156450-", - "A156451-", - "A156452-", - "A156453-", - "C156454-", - "G156455-", - "G156456-", - "G156457-", - "T156458-", - "G156459-", - "T156460-", - "C156461-", - "A156462-", - "T156463-", - "G156464-", - "T156465-", - "G156466-", - "A156467-", - "C156468-", - "G156469-", - "A156470-", - "G156471-", - "G156472-", - "G156473-", - "A156474-", - "G156475-", - "A156476-", - "A156477-", - "T156478-", - "C156479-", - "T156480-", - "T156481-", - "G156482-", - "A156483-", - "T156484-", - "A156485-", - "A156486-", - "G156487-", - "A156488-", - "G156489-", - "G156490-", - "C156491-", - "A156492-", - "T156493-", - "A156494-", - "A156495-", - "T156496-", - "C156497-", - "A156498-", - "A156499-", - "T156500-", - "G156501-", - "T156502-", - "T156503-", - "G156504-", - "T156505-", - "A156506-", - "A156507-", - "T156508-", - "C156509-", - "C156510-", - "G156511-", - "A156512-", - "T156513-", - "G156514-", - "T156515-", - "C156516-", - "C156517-", - "A156518-", - "C156519-", - "C156520-", - "T156521-", - "G156522-", - "G156523-", - "A156524-", - "G156525-", - "A156526-", - "A156527-", - "T156528-", - "T156529-", - "T156530-", - "G156531-", - "C156532-", - "C156533-", - "A156534-", - "A156535-", - "G156536-", - "G156537-", - "T156538-", - "C156539-", - "A156540-", - "G156541-", - "A156542-", - "T156543-", - "G156544-", - "T156545-", - "A156546-", - "G156547-", - "A156548-", - "G156549-", - "T156550-", - "T156551-", - "G156552-", - "G156553-", - "T156554-", - "A156555-", - "G156556-", - "T156557-", - "G156558-", - "A156559-", - "T156560-", - "A156561-", - "A156562-", - "C156563-", - "A156564-", - "C156565-", - "A156566-", - "A156567-", - "A156568-", - "A156569-", - "T156570-", - "G156571-", - "T156572-", - "G156573-", - "A156574-", - "A156575-", - "C156576-", - "A156577-", - "C156578-", - "T156579-", - "G156580-", - "C156581-", - "C156582-", - "C156583-", - "A156584-", - "C156585-", - "C156586-", - "T156587-", - "C156588-", - "A156589-", - "T156590-", - "A156591-", - "C156592-", - "A156593-", - "T156594-", - "A156595-", - "T156596-", - "A156597-", - "C156598-", - "C156599-", - "G156600-", - "C156601-", - "A156602-", - "A156603-", - "T156604-", - "C156605-", - "C156606-", - "C156607-", - "C156608-", - "A156609-", - "A156610-", - "T156611-", - "T156612-", - "A156613-", - "T156614-", - "T156615-", - "C156616-", - "T156617-", - "A156618-", - "A156619-", - "T156620-", - "A156621-", - "G156622-", - "A156623-", - "T156624-", - "G156625-", - "T156626-", - "C156627-", - "A156628-", - "T156629-", - "C156630-", - "A156631-", - "A156632-", - "T156633-", - "G156634-", - "T156635-", - "A156636-", - "G156637-", - "A156638-", - "A156639-", - "A156640-", - "A156641-", - "T156642-", - "G156643-", - "C156644-", - "C156645-", - "C156646-", - "A156647-", - "A156648-", - "C156649-", - "A156650-", - "G156651-", - "G156652-", - "A156653-", - "T156654-", - "C156655-", - "A156656-", - "T156657-", - "T156658-", - "T156659-", - "G156660-", - "A156661-", - "T156662-", - "A156663-", - "A156664-", - "G156665-", - "G156666-", - "T156667-", - "A156668-", - "A156669-", - "A156670-", - "G156671-", - "T156672-", - "G156673-", - "T156674-", - "A156675-", - "C156676-", - "C156677-", - "G156678-", - "G156679-", - "A156680-", - "A156681-", - "C156682-", - "A156683-", - "C156684-", - "A156685-", - "G156686-", - "A156687-", - "A156688-", - "C156689-", - "A156690-", - "A156691-", - "A156692-", - "T156693-", - "G156694-", - "T156695-", - "T156696-", - "C156697-", - "G156698-", - "T156699-", - "G156700-", - "T156701-", - "C156702-", - "A156703-", - "T156704-", - "C156705-", - "C156706-", - "T156707-", - "G156708-", - "G156709-", - "T156710-", - "T156711-", - "G156712-", - "G156713-", - "T156714-", - "A156715-", - "T156716-", - "A156717-", - "C156718-", - "G156719-", - "C156720-", - "T156721-", - "A156722-", - "C156723-", - "T156724-", - "G156725-", - "A156726-", - "T156727-", - "T156728-", - "C156729-", - "T156730-", - "T156731-", - "C156732-", - "A156733-", - "C156734-", - "A156735-", - "G156736-", - "A156737-", - "C156738-", - "T156739-", - "G156740-", - "A156741-", - "A156742-", - "G156743-", - "A156744-", - "T156745-", - "T156746-", - "G156747-", - "T156748-", - "C156749-", - "G156750-", - "A156751-", - "G156752-", - "A156753-", - "T156754-", - "T156755-", - "T156756-", - "G156757-", - "T156758-", - "G156759-", - "T156760-", - "A156761-", - "C156762-", - "C156763-", - "A156764-", - "A156765-", - "A156766-", - "A156767-", - "A156768-", - "A156769-", - "G156770-", - "G156771-", - "A156772-", - "G156773-", - "A156774-", - "T156775-", - "G156776-", - "T156777-", - "C156778-", - "C156779-", - "A156780-", - "T156781-", - "G156782-", - "C156783-", - "G156784-", - "G156785-", - "A156786-", - "T156787-", - "A156788-", - "C156789-", - "T156790-", - "T156791-", - "T156792-", - "G156793-", - "G156794-", - "T156795-", - "G156796-", - "G156797-", - "A156798-", - "A156799-", - "T156800-", - "A156801-", - "G156802-", - "A156803-", - "T156804-", - "G156805-", - "A156806-", - "A156807-", - "G156808-", - "G156809-", - "A156810-", - "A156811-", - "A156812-", - "T156813-", - "C156814-", - "C156815-", - "T156816-", - "A156817-", - "T156818-", - "T156819-", - "T156820-", - "G156821-", - "T156822-", - "A156823-", - "A156824-", - "A156825-", - "T156826-", - "C156827-", - "G156828-", - "T156829-", - "G156830-", - "T156831-", - "T156832-", - "G156833-", - "T156834-", - "G156835-", - "T156836-", - "T156837-", - "G156838-", - "G156839-", - "T156840-", - "G156841-", - "A156842-", - "A156843-", - "T156844-", - "A156845-", - "T156846-", - "T156847-", - "G156848-", - "C156849-", - "G156850-", - "A156851-", - "C156852-", - "T156853-", - "A156854-", - "C156855-", - "C156856-", - "T156857-", - "A156858-", - "C156859-", - "G156860-", - "T156861-", - "A156862-", - "A156863-", - "T156864-", - "T156865-", - "A156866-", - "T156867-", - "A156868-", - "G156869-", - "A156870-", - "C156871-", - "T156872-", - "T156873-", - "G156874-", - "A156875-", - "T156876-", - "C156877-", - "C156878-", - "A156879-", - "T156880-", - "T156881-", - "T156882-", - "C156883-", - "C156884-", - "T156885-", - "C156886-", - "C156887-", - "A156888-", - "T156889-", - "G156890-", - "C156891-", - "A156892-", - "A156893-", - "A156894-", - "C156895-", - "T156896-", - "A156897-", - "T156898-", - "C156899-", - "T156900-", - "A156901-", - "T156902-", - "C156903-", - "T156904-", - "A156905-", - "A156906-", - "A156907-", - "T156908-", - "G156909-", - "T156910-", - "A156911-", - "A156912-", - "T156913-", - "T156914-", - "A156915-", - "A156916-", - "T156917-", - "T156918-", - "A156919-", - "T156920-", - "G156921-", - "A156922-", - "T156923-", - "T156924-", - "T156925-", - "T156926-", - "G156927-", - "A156928-", - "T156929-", - "G156930-", - "A156931-", - "T156932-", - "A156933-", - "A156934-", - "T156935-", - "G156936-", - "T156937-", - "T156938-", - "A156939-", - "C156940-", - "C156941-", - "A156942-", - "T156943-", - "A156944-", - "C156945-", - "A156946-", - "T156947-", - "T156948-", - "A156949-", - "T156950-", - "A156951-", - "T156952-", - "C156953-", - "A156954-", - "C156955-", - "T156956-", - "A156957-", - "C156958-", - "T156959-", - "T156960-", - "G156961-", - "G156962-", - "T156963-", - "T156964-", - "A156965-", - "G156966-", - "T156967-", - "G156968-", - "T156969-", - "G156970-", - "T156971-", - "A156972-", - "T156973-", - "T156974-", - "A156975-", - "T156976-", - "T156977-", - "T156978-", - "A156979-", - "G156980-", - "T156981-", - "A156982-", - "T156983-", - "G156984-", - "G156985-", - "A156986-", - "A156987-", - "G156988-", - "A156989-", - "C156990-", - "C156991-", - "T156992-", - "A156993-", - "T156994-", - "T156995-", - "A156996-", - "A156997-", - "T156998-", - "A156999-", - "A157000-", - "T157001-", - "T157002-", - "A157003-", - "C157004-", - "T157005-", - "T157006-", - "A157007-", - "T157008-", - "C157009-", - "T157010-", - "T157011-", - "T157012-", - "T157013-", - "G157014-", - "A157015-", - "C157016-", - "G157017-", - "A157018-", - "T157019-", - "C157020-", - "T157021-", - "T157022-", - "G157023-", - "T157024-", - "T157025-", - "A157026-", - "T157027-", - "A157028-", - "A157029-", - "T157030-", - "T157031-", - "A157032-", - "T157033-", - "A157034-", - "A157035-", - "T157036-", - "A157037-", - "T157038-", - "A157039-", - "A157040-", - "A157041-", - "A157042-", - "A157043-", - "T157044-", - "A157045-", - "C157046-", - "T157047-", - "T157048-", - "A157049-", - "T157050-", - "G157051-", - "A157052-", - "C157053-", - "A157054-", - "T157055-", - "A157056-", - "G157057-", - "T157058-", - "A157059-", - "A157060-", - "C157061-", - "T157062-", - "C157063-", - "A157064-", - "T157065-", - "A157066-", - "A157067-", - "T157068-", - "T157069-", - "G157070-", - "C157071-", - "T157072-", - "G157073-", - "A157074-", - "C157075-", - "G157076-", - "C157077-", - "G157078-", - "A157079-", - "T157080-", - "A157081-", - "A157082-", - "A157083-", - "T157084-", - "T157085-", - "C157086-", - "G157087-", - "T157088-", - "A157089-", - "A157090-", - "T157091-", - "A157092-", - "A157093-", - "T157094-", - "C157095-", - "T157096-", - "G157097-", - "T157098-", - "T157099-", - "T157100-", - "T157101-", - "G157102-", - "T157103-", - "T157104-", - "C157105-", - "A157106-", - "A157107-", - "A157108-", - "T157109-", - "T157110-", - "T157111-", - "T157112-", - "T157113-", - "A157114-", - "T157115-", - "A157116-", - "A157117-", - "G157118-", - "G157119-", - "A157120-", - "A157121-", - "T157122-", - "C157123-", - "T157124-", - "A157125-", - "C157126-", - "A157127-", - "G157128-", - "G157129-", - "C157130-", - "A157131-", - "T157132-", - "A157133-", - "A157134-", - "A157135-", - "A157136-", - "A157137-", - "T157138-", - "A157139-", - "A157140-", - "A157141-", - "A157142-", - "A157143-", - "T157144-", - "A157145-", - "T157146-", - "A157147-", - "A157148-", - "T157149-", - "C157150-", - "T157151-", - "A157152-", - "T157153-", - "A157154-", - "A157155-", - "T157156-", - "A157157-", - "T157158-", - "A157159-", - "C157160-", - "T157161-", - "C157162-", - "T157163-", - "T157164-", - "A157165-", - "C157166-", - "A157167-", - "A157168-", - "C157169-", - "G157170-", - "C157171-", - "C157172-", - "A157173-", - "T157174-", - "C157175-", - "A157176-", - "T157177-", - "G157178-", - "A157179-", - "A157180-", - "T157181-", - "A157182-", - "G157183-", - "C157184-", - "A157185-", - "G157186-", - "T157187-", - "G157188-", - "A157189-", - "A157190-", - "T157191-", - "T157192-", - "A157193-", - "A157194-", - "T157195-", - "T157196-", - "G157197-", - "C157198-", - "T157199-", - "G157200-", - "T157201-", - "T157202-", - "A157203-", - "T157204-", - "T157205-", - "A157206-", - "T157207-", - "G157208-", - "G157209-", - "A157210-", - "T157211-", - "T157212-", - "T157213-", - "A157214-", - "G157215-", - "A157216-", - "A157217-", - "A157218-", - "T157219-", - "A157220-", - "G157221-", - "T157222-", - "G157223-", - "G157224-", - "A157225-", - "C157226-", - "G157227-", - "A157228-", - "T157229-", - "T157230-", - "T157231-", - "T157232-", - "G157233-", - "T157234-", - "G157235-", - "A157236-", - "T157237-", - "A157238-", - "T157239-", - "T157240-", - "A157241-", - "A157242-", - "T157243-", - "A157244-", - "T157245-", - "A157246-", - "G157247-", - "T157248-", - "T157249-", - "A157250-", - "T157251-", - "T157252-", - "A157253-", - "A157254-", - "T157255-", - "G157256-", - "A157257-", - "T157258-", - "G157259-", - "A157260-", - "A157261-", - "A157262-", - "G157263-", - "G157264-", - "A157265-", - "T157266-", - "A157267-", - "A157268-", - "A157269-", - "C157270-", - "G157271-", - "C157272-", - "G157273-", - "C157274-", - "A157275-", - "T157276-", - "A157277-", - "G157278-", - "A157279-", - "C157280-", - "T157281-", - "C157282-", - "A157283-", - "T157284-", - "C157285-", - "C157286-", - "T157287-", - "A157288-", - "T157289-", - "C157290-", - "T157291-", - "G157292-", - "G157293-", - "A157294-", - "G157295-", - "C157296-", - "C157297-", - "T157298-", - "C157299-", - "C157300-", - "G157301-", - "A157302-", - "A157303-", - "T157304-", - "A157305-", - "T157306-", - "T157307-", - "T157308-", - "T157309-", - "T157310-", - "T157311-", - "C157312-", - "C157313-", - "A157314-", - "T157315-", - "T157316-", - "C157317-", - "T157318-", - "G157319-", - "T157320-", - "T157321-", - "T157322-", - "T157323-", - "C157324-", - "C157325-", - "A157326-", - "A157327-", - "T157328-", - "A157329-", - "A157330-", - "T157331-", - "T157332-", - "T157333-", - "T157334-", - "A157335-", - "T157336-", - "C157337-", - "G157338-", - "A157339-", - "T157340-", - "T157341-", - "C157342-", - "T157343-", - "A157344-", - "A157345-", - "T157346-", - "G157347-", - "A157348-", - "A157349-", - "T157350-", - "A157351-", - "C157352-", - "G157353-", - "A157354-", - "A157355-", - "G157356-", - "T157357-", - "T157358-", - "A157359-", - "A157360-", - "T157361-", - "C157362-", - "T157363-", - "A157364-", - "A157365-", - "G157366-", - "T157367-", - "C157368-", - "A157369-", - "T157370-", - "T157371-", - "T157372-", - "A157373-", - "G157374-", - "A157375-", - "T157376-", - "T157377-", - "A157378-", - "T157379-", - "C157380-", - "A157381-", - "A157382-", - "A157383-", - "G157384-", - "T157385-", - "G157386-", - "T157387-", - "T157388-", - "A157389-", - "A157390-", - "C157391-", - "T157392-", - "A157393-", - "T157394-", - "T157395-", - "T157396-", - "G157397-", - "A157398-", - "T157399-", - "C157400-", - "G157401-", - "A157402-", - "T157403-", - "T157404-", - "A157405-", - "C157406-", - "A157407-", - "T157408-", - "T157409-", - "T157410-", - "A157411-", - "T157412-", - "G157413-", - "G157414-", - "G157415-", - "A157416-", - "T157417-", - "A157418-", - "C157419-", - "C157420-", - "T157421-", - "T157422-", - "T157423-", - "G157424-", - "A157425-", - "G157426-", - "C157427-", - "C157428-", - "T157429-", - "A157430-", - "A157431-", - "C157432-", - "T157433-", - "A157434-", - "A157435-", - "C157436-", - "A157437-", - "A157438-", - "T157439-", - "A157440-", - "A157441-", - "C157442-", - "G157443-", - "T157444-", - "G157445-", - "A157446-", - "A157447-", - "A157448-", - "T157449-", - "A157450-", - "T157451-", - "A157452-", - "T157453-", - "T157454-", - "C157455-", - "T157456-", - "T157457-", - "T157458-", - "C157459-", - "A157460-", - "A157461-", - "C157462-", - "C157463-", - "G157464-", - "C157465-", - "T157466-", - "G157467-", - "A157468-", - "T157469-", - "T157470-", - "T157471-", - "T157472-", - "T157473-", - "T157474-", - "T157475-", - "A157476-", - "C157477-", - "A157478-", - "A157479-", - "A157480-", - "T157481-", - "T157482-", - "G157483-", - "G157484-", - "A157485-", - "T157486-", - "C157487-", - "T157488-", - "G157489-", - "T157490-", - "C157491-", - "A157492-", - "T157493-", - "T157494-", - "A157495-", - "C157496-", - "T157497-", - "G157498-", - "A157499-", - "G157500-", - "T157501-", - "G157502-", - "C157503-", - "G157504-", - "A157505-", - "A157506-", - "A157507-", - "A157508-", - "A157509-", - "T157510-", - "A157511-", - "C157512-", - "A157513-", - "T157514-", - "A157515-", - "C157516-", - "T157517-", - "T157518-", - "A157519-", - "A157520-", - "A157521-", - "A157522-", - "A157523-", - "T157524-", - "C157525-", - "T157526-", - "T157527-", - "T157528-", - "G157529-", - "T157530-", - "T157531-", - "T157532-", - "T157533-", - "A157534-", - "G157535-", - "A157536-", - "A157537-", - "A157538-", - "C157539-", - "T157540-", - "G157541-", - "T157542-", - "A157543-", - "T157544-", - "C157545-", - "G157546-", - "A157547-", - "T157548-", - "T157549-", - "T157550-", - "C157551-", - "T157552-", - "A157553-", - "C157554-", - "A157555-", - "T157556-", - "A157557-", - "T157558-", - "A157559-", - "C157560-", - "G157561-", - "C157562-", - "T157563-", - "G157564-", - "A157565-", - "T157566-", - "A157567-", - "A157568-", - "A157569-", - "T157570-", - "A157571-", - "T157572-", - "A157573-", - "A157574-", - "T157575-", - "A157576-", - "A157577-", - "C157578-", - "A157579-", - "A157580-", - "G157581-", - "A157582-", - "A157583-", - "A157584-", - "A157585-", - "T157586-", - "A157587-", - "G157588-", - "A157589-", - "A157590-", - "T157591-", - "T157592-", - "A157593-", - "G157594-", - "C157595-", - "A157596-", - "T157597-", - "C157598-", - "G157599-", - "T157600-", - "T157601-", - "T157602-", - "A157603-", - "A157604-", - "C157605-", - "A157606-", - "C157607-", - "A157608-", - "A157609-", - "T157610-", - "A157611-", - "T157612-", - "T157613-", - "A157614-", - "C157615-", - "G157616-", - "A157617-", - "A157618-", - "A157619-", - "T157620-", - "A157621-", - "T157622-", - "T157623-", - "T157624-", - "T157625-", - "G157626-", - "A157627-", - "G157628-", - "A157629-", - "C157630-", - "T157631-", - "C157632-", - "A157633-", - "T157634-", - "C157635-", - "A157636-", - "A157637-", - "C157638-", - "A157639-", - "A157640-", - "T157641-", - "G157642-", - "A157643-", - "A157644-", - "A157645-", - "A157646-", - "C157647-", - "T157648-", - "T157649-", - "T157650-", - "A157651-", - "A157652-", - "A157653-", - "T157654-", - "A157655-", - "C157656-", - "T157657-", - "T157658-", - "A157659-", - "A157660-", - "C157661-", - "A157662-", - "G157663-", - "A157664-", - "G157665-", - "G157666-", - "A157667-", - "A157668-", - "T157669-", - "C157670-", - "A157671-", - "A157672-", - "T157673-", - "G157674-", - "A157675-", - "T157676-", - "A157677-", - "A157678-", - "A157679-", - "A157680-", - "A157681-", - "T157682-", - "T157683-", - "T157684-", - "T157685-", - "A157686-", - "A157687-", - "G157688-", - "C157689-", - "G157690-", - "A157691-", - "T157692-", - "G157693-", - "A157694-", - "T157695-", - "A157696-", - "T157697-", - "G157698-", - "T157699-", - "T157700-", - "A157701-", - "T157702-", - "A157703-", - "T157704-", - "A157705-", - "T157706-", - "A157707-", - "A157708-", - "A157709-", - "A157710-", - "A157711-", - "A157712-", - "T157713-", - "G157714-", - "A157715-", - "G157716-", - "G157717-", - "A157718-", - "T157719-", - "T157720-", - "T157721-", - "C157722-", - "A157723-", - "C157724-", - "C157725-", - "C157726-", - "C157727-", - "A157728-", - "C157729-", - "T157730-", - "G157731-", - "A157732-", - "T157733-", - "T157734-", - "C157735-", - "T157736-", - "C157737-", - "A157738-", - "T157739-", - "T157740-", - "A157741-", - "A157742-", - "A157743-", - "T157744-", - "G157745-", - "G157746-", - "T157747-", - "T157748-", - "A157749-", - "G157750-", - "A157751-", - "G157752-", - "A157753-", - "G157754-", - "T157755-", - "A157756-", - "C157757-", - "A157758-", - "C157759-", - "C157760-", - "A157761-", - "A157762-", - "C157763-", - "C157764-", - "A157765-", - "T157766-", - "G157767-", - "T157768-", - "A157769-", - "C157770-", - "C157771-", - "G157772-", - "T157773-", - "C157774-", - "G157775-", - "A157776-", - "G157777-", - "T157778-", - "T157779-", - "A157780-", - "C157781-", - "T157782-", - "T157783-", - "A157784-", - "G157785-", - "A157786-", - "T157787-", - "G157788-", - "C157789-", - "C157790-", - "T157791-", - "C157792-", - "A157793-", - "G157794-", - "A157795-", - "A157796-", - "T157797-", - "A157798-", - "T157799-", - "C157800-", - "A157801-", - "T157802-", - "T157803-", - "T157804-", - "C157805-", - "T157806-", - "T157807-", - "T157808-", - "C157809-", - "C157810-", - "C157811-", - "C157812-", - "A157813-", - "C157814-", - "A157815-", - "A157816-", - "G157817-", - "T157818-", - "T157819-", - "A157820-", - "T157821-", - "A157822-", - "A157823-", - "A157824-", - "A157825-", - "T157826-", - "C157827-", - "A157828-", - "C157829-", - "T157830-", - "T157831-", - "T157832-", - "A157833-", - "T157834-", - "A157835-", - "G157836-", - "T157837-", - "C157838-", - "A157839-", - "T157840-", - "C157841-", - "G157842-", - "A157843-", - "C157844-", - "T157845-", - "G157846-", - "G157847-", - "T157848-", - "T157849-", - "A157850-", - "G157851-", - "T157852-", - "T157853-", - "C157854-", - "A157855-", - "A157856-", - "T157857-", - "C157858-", - "T157859-", - "A157860-", - "C157861-", - "G157862-", - "A157863-", - "A157864-", - "T157865-", - "G157866-", - "T157867-", - "A157868-", - "T157869-", - "A157870-", - "A157871-", - "C157872-", - "A157873-", - "T157874-", - "T157875-", - "C157876-", - "T157877-", - "T157878-", - "A157879-", - "A157880-", - "A157881-", - "C157882-", - "A157883-", - "A157884-", - "T157885-", - "A157886-", - "T157887-", - "A157888-", - "G157889-", - "C157890-", - "A157891-", - "T157892-", - "T157893-", - "C157894-", - "T157895-", - "T157896-", - "G157897-", - "G157898-", - "A157899-", - "T157900-", - "A157901-", - "A157902-", - "A157903-", - "T157904-", - "C157905-", - "A157906-", - "T157907-", - "T157908-", - "T157909-", - "C157910-", - "C157911-", - "T157912-", - "A157913-", - "G157914-", - "A157915-", - "T157916-", - "A157917-", - "C157918-", - "C157919-", - "A157920-", - "T157921-", - "A157922-", - "T157923-", - "C157924-", - "A157925-", - "T157926-", - "C157927-", - "G157928-", - "A157929-", - "G157930-", - "T157931-", - "T157932-", - "G157933-", - "A157934-", - "T157935-", - "A157936-", - "T157937-", - "C157938-", - "T157939-", - "A157940-", - "T157941-", - "C157942-", - "G157943-", - "G157944-", - "T157945-", - "A157946-", - "T157947-", - "A157948-", - "A157949-", - "G157950-", - "T157951-", - "A157952-", - "A157953-", - "T157954-", - "T157955-", - "C157956-", - "A157957-", - "C157958-", - "A157959-", - "T157960-", - "G157961-", - "A157962-", - "T157963-", - "A157964-", - "A157965-", - "G157966-", - "A157967-", - "T157968-", - "T157969-", - "T157970-", - "C157971-", - "C157972-", - "A157973-", - "T157974-", - "A157975-", - "A157976-", - "A157977-", - "C157978-", - "T157979-", - "G157980-", - "C157981-", - "T157982-", - "A157983-", - "C157984-", - "A157985-", - "A157986-", - "T157987-", - "C157988-", - "A157989-", - "T157990-", - "A157991-", - "A157992-", - "A157993-", - "A157994-", - "A157995-", - "A157996-", - "A157997-", - "T157998-", - "T157999-", - "C158000-", - "A158001-", - "T158002-", - "G158003-", - "G158004-", - "G158005-", - "A158006-", - "A158007-", - "A158008-", - "T158009-", - "G158010-", - "A158011-", - "T158012-", - "A158013-", - "T158014-", - "C158015-", - "T158016-", - "T158017-", - "C158018-", - "A158019-", - "C158020-", - "G158021-", - "T158022-", - "A158023-", - "G158024-", - "A158025-", - "T158026-", - "A158027-", - "T158028-", - "A158029-", - "G158030-", - "G158031-", - "T158032-", - "G158033-", - "T158034-", - "A158035-", - "G158036-", - "T158037-", - "T158038-", - "T158039-", - "C158040-", - "G158041-", - "C158042-", - "A158043-", - "G158044-", - "T158045-", - "G158046-", - "A158047-", - "C158048-", - "C158049-", - "G158050-", - "T158051-", - "C158052-", - "C158053-", - "T158054-", - "G158055-", - "G158056-", - "A158057-", - "T158058-", - "A158059-", - "A158060-", - "T158061-", - "A158062-", - "T158063-", - "T158064-", - "A158065-", - "T158066-", - "C158067-", - "T158068-", - "A158069-", - "T158070-", - "A158071-", - "T158072-", - "G158073-", - "A158074-", - "T158075-", - "G158076-", - "G158077-", - "G158078-", - "T158079-", - "G158080-", - "G158081-", - "A158082-", - "T158083-", - "A158084-", - "T158085-", - "G158086-", - "A158087-", - "T158088-", - "C158089-", - "A158090-", - "G158091-", - "T158092-", - "C158093-", - "C158094-", - "C158095-", - "T158096-", - "G158097-", - "T158098-", - "A158099-", - "T158100-", - "A158101-", - "G158102-", - "A158103-", - "A158104-", - "G158105-", - "T158106-", - "T158107-", - "C158108-", - "A158109-", - "A158110-", - "A158111-", - "G158112-", - "G158113-", - "T158114-", - "T158115-", - "A158116-", - "T158117-", - "A158118-", - "G158119-", - "C158120-", - "G158121-", - "T158122-", - "A158123-", - "C158124-", - "A158125-", - "A158126-", - "T158127-", - "A158128-", - "C158129-", - "A158130-", - "T158131-", - "G158132-", - "T158133-", - "A158134-", - "C158135-", - "T158136-", - "A158137-", - "A158138-", - "T158139-", - "T158140-", - "C158141-", - "T158142-", - "T158143-", - "G158144-", - "G158145-", - "A158146-", - "T158147-", - "A158148-", - "T158149-", - "A158150-", - "T158151-", - "G158152-", - "A158153-", - "T158154-", - "A158155-", - "T158156-", - "A158157-", - "C158158-", - "C158159-", - "A158160-", - "G158161-", - "A158162-", - "G158163-", - "C158164-", - "T158165-", - "A158166-", - "A158167-", - "A158168-", - "A158169-", - "A158170-", - "T158171-", - "A158172-", - "T158173-", - "C158174-", - "A158175-", - "T158176-", - "C158177-", - "G158178-", - "T158179-", - "T158180-", - "C158181-", - "T158182-", - "A158183-", - "A158184-", - "T158185-", - "T158186-", - "G158187-", - "C158188-", - "G158189-", - "G158190-", - "A158191-", - "G158192-", - "G158193-", - "A158194-", - "G158195-", - "T158196-", - "T158197-", - "G158198-", - "C158199-", - "C158200-", - "A158201-", - "A158202-", - "T158203-", - "G158204-", - "A158205-", - "C158206-", - "G158207-", - "A158208-", - "A158209-", - "T158210-", - "A158211-", - "C158212-", - "A158213-", - "T158214-", - "T158215-", - "T158216-", - "A158217-", - "T158218-", - "T158219-", - "G158220-", - "T158221-", - "A158222-", - "T158223-", - "A158224-", - "G158225-", - "G158226-", - "C158227-", - "G158228-", - "G158229-", - "T158230-", - "A158231-", - "T158232-", - "A158233-", - "C158234-", - "G158235-", - "C158236-", - "G158237-", - "A158238-", - "T158239-", - "C158240-", - "A158241-", - "G158242-", - "G158243-", - "A158244-", - "G158245-", - "T158246-", - "C158247-", - "A158248-", - "T158249-", - "C158250-", - "G158251-", - "T158252-", - "T158253-", - "G158254-", - "A158255-", - "T158256-", - "A158257-", - "T158258-", - "C158259-", - "T158260-", - "A158261-", - "G158262-", - "T158263-", - "A158264-", - "T158265-", - "C158266-", - "G158267-", - "A158268-", - "T158269-", - "A158270-", - "G158271-", - "A158272-", - "T158273-", - "G158274-", - "G158275-", - "A158276-", - "A158277-", - "G158278-", - "C158279-", - "C158280-", - "A158281-", - "T158282-", - "C158283-", - "A158284-", - "A158285-", - "A158286-", - "A158287-", - "C158288-", - "C158289-", - "A158290-", - "T158291-", - "A158292-", - "T158293-", - "T158294-", - "G158295-", - "G158296-", - "C158297-", - "A158298-", - "G158299-", - "A158300-", - "A158301-", - "G158302-", - "T158303-", - "A158304-", - "T158305-", - "G158306-", - "C158307-", - "T158308-", - "A158309-", - "A158310-", - "A158311-", - "A158312-", - "T158313-", - "G158314-", - "T158315-", - "G158316-", - "C158317-", - "G158318-", - "A158319-", - "A158320-", - "C158321-", - "C158322-", - "A158323-", - "A158324-", - "A158325-", - "A158326-", - "T158327-", - "G158328-", - "T158329-", - "G158330-", - "A158331-", - "T158332-", - "A158333-", - "T158334-", - "G158335-", - "G158336-", - "G158337-", - "G158338-", - "T158339-", - "T158340-", - "G158341-", - "C158342-", - "G158343-", - "A158344-", - "T158345-", - "T158346-", - "T158347-", - "T158348-", - "A158349-", - "A158350-", - "A158351-", - "C158352-", - "G158353-", - "G158354-", - "A158355-", - "T158356-", - "T158357-", - "A158358-", - "A158359-", - "T158360-", - "A158361-", - "T158362-", - "A158363-", - "T158364-", - "G158365-", - "T158366-", - "C158367-", - "A158368-", - "T158369-", - "A158370-", - "G158371-", - "G158372-", - "T158373-", - "G158374-", - "G158375-", - "A158376-", - "G158377-", - "T158378-", - "C158379-", - "G158380-", - "T158381-", - "T158382-", - "A158383-", - "A158384-", - "A158385-", - "G158386-", - "G158387-", - "T158388-", - "G158389-", - "A158390-", - "C158391-", - "A158392-", - "C158393-", - "A158394-", - "C158395-", - "A158396-", - "T158397-", - "A158398-", - "T158399-", - "A158400-", - "C158401-", - "C158402-", - "A158403-", - "A158404-", - "C158405-", - "G158406-", - "C158407-", - "A158408-", - "C158409-", - "T158410-", - "A158411-", - "G158412-", - "A158413-", - "G158414-", - "A158415-", - "G158416-", - "T158417-", - "T158418-", - "T158419-", - "A158420-", - "T158421-", - "C158422-", - "A158423-", - "G158424-", - "A158425-", - "A158426-", - "G158427-", - "A158428-", - "T158429-", - "G158430-", - "G158431-", - "A158432-", - "T158433-", - "G158434-", - "G158435-", - "A158436-", - "T158437-", - "G158438-", - "A158439-", - "A158440-", - "T158441-", - "C158442-", - "A158443-", - "T158444-", - "C158445-", - "A158446-", - "A158447-", - "C158448-", - "G158449-", - "T158450-", - "C158451-", - "T158452-", - "T158453-", - "C158454-", - "C158455-", - "A158456-", - "A158457-", - "T158458-", - "A158459-", - "A158460-", - "A158461-", - "A158462-", - "A158463-", - "T158464-", - "G158465-", - "T158466-", - "C158467-", - "C158468-", - "A158469-", - "A158470-", - "T158471-", - "A158472-", - "T158473-", - "G158474-", - "T158475-", - "C158476-", - "G158477-", - "A158478-", - "C158479-", - "G158480-", - "A158481-", - "T158482-", - "T158483-", - "G158484-", - "T158485-", - "T158486-", - "C158487-", - "A158488-", - "T158489-", - "G158490-", - "C158491-", - "T158492-", - "G158493-", - "G158494-", - "A158495-", - "A158496-", - "A158497-", - "G158498-", - "A158499-", - "T158500-", - "T158501-", - "T158502-", - "A158503-", - "T158504-", - "A158505-", - "T158506-", - "A158507-", - "T158508-", - "C158509-", - "T158510-", - "A158511-", - "G158512-", - "A158513-", - "G158514-", - "G158515-", - "T158516-", - "T158517-", - "A158518-", - "C158519-", - "A158520-", - "A158521-", - "C158522-", - "A158523-", - "A158524-", - "T158525-", - "A158526-", - "G158527-", - "T158528-", - "A158529-", - "G158530-", - "T158531-", - "G158532-", - "T158533-", - "A158534-", - "G158535-", - "T158536-", - "T158537-", - "A158538-", - "A158539-", - "T158540-", - "G158541-", - "T158542-", - "A158543-", - "A158544-", - "T158545-", - "A158546-", - "T158547-", - "C158548-", - "G158549-", - "A158550-", - "A158551-", - "T158552-", - "C158553-", - "T158554-", - "A158555-", - "G158556-", - "T158557-", - "C158558-", - "C158559-", - "T158560-", - "T158561-", - "A158562-", - "G158563-", - "C158564-", - "T158565-", - "A158566-", - "T158567-", - "A158568-", - "A158569-", - "T158570-", - "C158571-", - "C158572-", - "G158573-", - "A158574-", - "T158575-", - "A158576-", - "T158577-", - "A158578-", - "T158579-", - "G158580-", - "A158581-", - "T158582-", - "G158583-", - "A158584-", - "A158585-", - "T158586-", - "G158587-", - "G158588-", - "A158589-", - "C158590-", - "C158591-", - "A158592-", - "A158593-", - "A158594-", - "T158595-", - "T158596-", - "A158597-", - "T158598-", - "C158599-", - "A158600-", - "T158601-", - "C158602-", - "A158603-", - "T158604-", - "T158605-", - "A158606-", - "A158607-", - "A158608-", - "T158609-", - "A158610-", - "T158611-", - "T158612-", - "C158613-", - "C158614-", - "T158615-", - "A158616-", - "G158617-", - "A158618-", - "A158619-", - "T158620-", - "T158621-", - "A158622-", - "A158623-", - "T158624-", - "C158625-", - "C158626-", - "T158627-", - "G158628-", - "C158629-", - "T158630-", - "C158631-", - "T158632-", - "A158633-", - "G160043-", - "A162901-", - "T163190-", - "A163191-", - "A163192-", - "C163193-", - "T163194-", - "A163195-", - "A163196-", - "C163197-", - "T165054-", - "C165055-", - "T166655-", - "T166656-", - "T166711-", - "T168120-", - "T168214-", - "A168956-", - "A169024-", - "T169162-", - "A169581-", - "G169718-", - "A169719-", - "T169720-", - "T169721-", - "C169722-", - "A169723-", - "A169777-", - "G169778-", - "A169779-", - "A169780-", - "G169781-", - "A169782-", - "T169783-", - "A169784-", - "T169785-", - "C169786-", - "A169787-", - "T169788-", - "G169789-", - "A169790-", - "A169791-", - "T169792-", - "G169793-", - "A169794-", - "A169795-", - "A169796-", - "A170723-", - "T170897-", - "T170898-", - "G170914-", - "T172059-", - "T172079-", - "T172080-", - "T172661-", - "G173004-", - "T173005-", - "G173006-", - "A173007-", - "C173008-", - "A173009-", - "T173010-", - "G173011-", - "A173012-", - "T173013-", - "G173014-", - "T173015-", - "C173016-", - "G173017-", - "T173018-", - "T173019-", - "A173020-", - "A173021-", - "A173022-", - "T173023-", - "T173024-", - "T173025-", - "G173026-", - "A173027-", - "C173028-", - "A173029-", - "A173030-", - "T173031-", - "C173032-", - "G173033-", - "T173034-", - "G173035-", - "T173036-", - "C173037-", - "T173038-", - "G173039-", - "T173040-", - "C173041-", - "T173042-", - "C173043-", - "A173044-", - "G173045-", - "A173046-", - "A173047-", - "T173048-", - "C173049-", - "A173050-", - "A173051-", - "A173052-", - "T173053-", - "A173054-", - "T173055-", - "A173056-", - "G173057-", - "A173058-", - "T173059-", - "C173060-", - "T173061-", - "T173062-", - "A173063-", - "T173064-", - "C173065-", - "T173066-", - "C173067-", - "G173068-", - "T173069-", - "A173070-", - "T173071-", - "C173072-", - "C173073-", - "A173074-", - "C173075-", - "A173076-", - "A173077-", - "A173078-", - "T173079-", - "A173080-", - "G173081-", - "T173082-", - "A173083-", - "A173084-", - "A173085-", - "T173086-", - "G173087-", - "A173088-", - "G173089-", - "A173090-", - "G173091-", - "A173092-", - "T173093-", - "C173094-", - "T173095-", - "A173096-", - "C173097-", - "T173098-", - "G173099-", - "G173100-", - "T173101-", - "A173102-", - "A173103-", - "A173104-", - "A173105-", - "T173106-", - "G173107-", - "G173108-", - "T173109-", - "A173110-", - "T173111-", - "G173112-", - "T173113-", - "C173114-", - "C173115-", - "C173116-", - "A173117-", - "A173118-", - "T173119-", - "A173120-", - "T173121-", - "T173122-", - "A173123-", - "A173124-", - "T173125-", - "G173126-", - "C173127-", - "A173128-", - "T173129-", - "T173130-", - "T173131-", - "A173132-", - "T173133-", - "T173134-", - "T173135-", - "C173136-", - "T173137-", - "A173138-", - "G173139-", - "T173140-", - "A173141-", - "A173142-", - "C173143-", - "G173144-", - "T173145-", - "A173146-", - "A173147-", - "A173148-", - "C173149-", - "A173150-", - "C173151-", - "A173152-", - "G173153-", - "A173154-", - "A173155-", - "T173156-", - "T173157-", - "A173158-", - "T173159-", - "A173160-", - "T173161-", - "G173162-", - "G173163-", - "A173164-", - "G173165-", - "C173166-", - "G173167-", - "G173168-", - "A173169-", - "C173170-", - "A173171-", - "T173172-", - "C173173-", - "G173174-", - "A173175-", - "C173176-", - "G173177-", - "C173178-", - "C173179-", - "T173180-", - "T173181-", - "A173182-", - "G173183-", - "A173184-", - "A173185-", - "A173186-", - "T173187-", - "A173188-", - "A173189-", - "G173190-", - "A173191-", - "G173192-", - "A173193-", - "C173194-", - "T173195-", - "T173196-", - "A173197-", - "A173198-", - "A173199-", - "C173200-", - "A173201-", - "A173202-", - "C173203-", - "G173204-", - "G173205-", - "A173206-", - "C173207-", - "A173208-", - "C173209-", - "C173210-", - "T173211-", - "G173212-", - "G173213-", - "A173214-", - "A173215-", - "T173216-", - "T173217-", - "A173218-", - "T173219-", - "T173220-", - "A173221-", - "C173222-", - "C173223-", - "A173224-", - "T173225-", - "A173226-", - "G173227-", - "A173228-", - "A173229-", - "G173230-", - "A173231-", - "T173232-", - "G173233-", - "T173234-", - "T173235-", - "A173236-", - "G173237-", - "A173238-", - "A173239-", - "A173240-", - "A173241-", - "A173242-", - "A173243-", - "T173244-", - "G173245-", - "A173246-", - "T173247-", - "G173248-", - "C173249-", - "T173250-", - "G173251-", - "G173252-", - "T173253-", - "T173254-", - "A173255-", - "T173256-", - "T173257-", - "A173258-", - "T173259-", - "A173260-", - "C173261-", - "A173262-", - "T173263-", - "G173264-", - "T173265-", - "G173266-", - "T173267-", - "T173268-", - "T173269-", - "T173270-", - "A173271-", - "G173272-", - "A173273-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "A173300-", - "T173301-", - "A173302-", - "T173303-", - "A173304-", - "T173305-", - "A173306-", - "T173307-", - "A173308-", - "T173309-", - "A173310-", - "T173311-", - "A173312-", - "T173313-", - "A173314-", - "T173315-", - "A173316-", - "T173317-", - "G173318-", - "G173319-", - "G173320-", - "C173321-", - "A173322-", - "A173323-", - "A173324-", - "A173325-", - "C173326-", - "A173327-", - "T173328-", - "A173329-", - "T173330-", - "A173331-", - "A173332-", - "C173333-", - "G173334-", - "T173335-", - "A173336-", - "A173337-", - "C173338-", - "C173339-", - "A173340-", - "G173341-", - "A173342-", - "A173343-", - "T173344-", - "T173345-", - "A173346-", - "T173347-", - "A173348-", - "A173349-", - "A173350-", - "A173351-", - "T173352-", - "T173353-", - "A173354-", - "G173355-", - "A173356-", - "G173357-", - "G173358-", - "T173359-", - "A173360-", - "C173361-", - "G173362-", - "G173363-", - "G173364-", - "A173365-", - "T173366-", - "A173367-", - "G173368-", - "A173369-", - "A173370-", - "T173371-", - "A173372-", - "A173373-", - "T173374-", - "A173375-", - "C173376-", - "C173377-", - "T173378-", - "C173379-", - "C173380-", - "T173381-", - "A173382-", - "C173383-", - "T173384-", - "A173385-", - "T173386-", - "G173387-", - "A173388-", - "A173389-", - "A173390-", - "T173391-", - "T173392-", - "A173393-", - "C173394-", - "C173395-", - "A173396-", - "G173397-", - "A173398-", - "A173399-", - "G173400-", - "G173401-", - "A173402-", - "G173403-", - "T173404-", - "A173405-", - "G173406-", - "T173407-", - "A173408-", - "A173409-", - "C173410-", - "T173411-", - "T173412-", - "C173413-", - "A173414-", - "A173415-", - "T173416-", - "A173417-", - "G173418-", - "G173419-", - "T173420-", - "A173421-", - "G173422-", - "T173423-", - "A173424-", - "A173425-", - "T173426-", - "T173427-", - "T173428-", - "G173429-", - "A173430-", - "C173431-", - "T173432-", - "A173433-", - "T173434-", - "T173435-", - "G173436-", - "C173437-", - "A173438-", - "T173439-", - "G173440-", - "T173441-", - "A173442-", - "G173443-", - "A173444-", - "G173445-", - "T173446-", - "A173447-", - "T173448-", - "C173449-", - "G173450-", - "T173451-", - "T173452-", - "G173453-", - "A173454-", - "G173455-", - "A173456-", - "C173457-", - "T173458-", - "T173459-", - "C173460-", - "C173461-", - "C173462-", - "A173463-", - "C173464-", - "A173465-", - "A173466-", - "C173467-", - "G173468-", - "G173469-", - "A173470-", - "C173471-", - "A173472-", - "C173473-", - "C173474-", - "G173475-", - "A173476-", - "C173477-", - "G173478-", - "T173479-", - "C173480-", - "T173481-", - "T173482-", - "T173483-", - "T173484-", - "G173485-", - "G173486-", - "A173487-", - "T173488-", - "A173489-", - "A173490-", - "G173491-", - "T173492-", - "A173493-", - "A173494-", - "T173495-", - "G173496-", - "G173497-", - "T173498-", - "A173499-", - "T173500-", - "A173501-", - "T173502-", - "G173503-", - "T173504-", - "A173505-", - "T173506-", - "T173507-", - "A173508-", - "C173509-", - "G173510-", - "A173511-", - "A173512-", - "G173513-", - "A173514-", - "A173515-", - "G173516-", - "A173517-", - "A173518-", - "G173519-", - "A173520-", - "C173521-", - "G173522-", - "A173523-", - "G173524-", - "G173525-", - "A173526-", - "C173527-", - "G173528-", - "G173529-", - "A173530-", - "G173531-", - "A173532-", - "C173533-", - "G173534-", - "G173535-", - "T173536-", - "A173537-", - "G173538-", - "A173539-", - "A173540-", - "T173541-", - "A173542-", - "A173543-", - "G173544-", - "T173545-", - "G173546-", - "T173547-", - "A173548-", - "G173549-", - "C173550-", - "A173551-", - "A173552-", - "A173553-", - "T173554-", - "A173555-", - "A173556-", - "A173557-", - "A173558-", - "T173559-", - "C173560-", - "T173561-", - "A173562-", - "T173563-", - "A173564-", - "T173565-", - "G173566-", - "A173567-", - "C173568-", - "C173569-", - "G173570-", - "A173571-", - "T173572-", - "A173573-", - "A173574-", - "G173575-", - "A173576-", - "G173577-", - "A173578-", - "C173579-", - "G173580-", - "T173581-", - "G173582-", - "T173583-", - "T173584-", - "A173585-", - "T173586-", - "T173587-", - "A173588-", - "C173589-", - "A173590-", - "T173591-", - "C173592-", - "C173593-", - "T173594-", - "G173595-", - "G173596-", - "T173597-", - "T173598-", - "A173599-", - "A173600-", - "A173601-", - "C173602-", - "A173603-", - "T173604-", - "T173605-", - "A173606-", - "A173607-", - "T173608-", - "C173609-", - "C173610-", - "T173611-", - "G173612-", - "T173613-", - "C173614-", - "A173615-", - "A173616-", - "G173617-", - "G173618-", - "A173619-", - "A173620-", - "G173621-", - "A173622-", - "A173623-", - "G173624-", - "A173625-", - "T173626-", - "G173627-", - "C173628-", - "T173629-", - "A173630-", - "C173631-", - "A173632-", - "A173633-", - "C173634-", - "G173635-", - "T173636-", - "T173637-", - "T173638-", - "A173639-", - "C173640-", - "G173641-", - "T173642-", - "G173643-", - "T173644-", - "A173645-", - "T173646-", - "G173647-", - "G173648-", - "C173649-", - "G173650-", - "T173651-", - "T173652-", - "T173653-", - "A173654-", - "C173655-", - "T173656-", - "A173657-", - "T173658-", - "T173659-", - "C173660-", - "C173661-", - "T173662-", - "A173663-", - "G173664-", - "C173665-", - "A173666-", - "T173667-", - "C173668-", - "A173669-", - "G173670-", - "C173671-", - "A173672-", - "A173673-", - "A173674-", - "A173675-", - "C173676-", - "A173677-", - "G173678-", - "T173679-", - "T173680-", - "A173681-", - "C173682-", - "T173683-", - "G173684-", - "T173685-", - "T173686-", - "A173687-", - "G173688-", - "T173689-", - "A173690-", - "A173691-", - "A173692-", - "C173693-", - "G173694-", - "T173695-", - "G173696-", - "A173697-", - "A173698-", - "T173699-", - "G173700-", - "T173701-", - "A173702-", - "T173703-", - "G173704-", - "T173705-", - "T173706-", - "G173707-", - "T173708-", - "T173709-", - "A173710-", - "C173711-", - "A173712-", - "T173713-", - "T173714-", - "T173715-", - "C173716-", - "C173717-", - "A173718-", - "T173719-", - "A173720-", - "T173721-", - "C173722-", - "A173723-", - "A173724-", - "T173725-", - "T173726-", - "G173727-", - "A173728-", - "G173729-", - "T173730-", - "T173731-", - "T173732-", - "A173733-", - "T173734-", - "A173735-", - "A173736-", - "G173737-", - "A173738-", - "A173739-", - "T173740-", - "T173741-", - "T173742-", - "T173743-", - "T173744-", - "T173745-", - "A173746-", - "T173747-", - "A173748-", - "C173749-", - "A173750-", - "T173751-", - "T173752-", - "A173753-", - "T173754-", - "C173755-", - "T173756-", - "T173757-", - "C173758-", - "C173759-", - "A173760-", - "A173761-", - "C173762-", - "A173763-", - "A173764-", - "A173765-", - "C173766-", - "A173767-", - "A173768-", - "T173769-", - "T173770-", - "G173771-", - "A173772-", - "C173773-", - "G173774-", - "A173775-", - "A173776-", - "C173777-", - "G173778-", - "T173779-", - "A173780-", - "T173781-", - "T173782-", - "G173783-", - "C173784-", - "T173785-", - "A173786-", - "T173787-", - "G173788-", - "A173789-", - "T173790-", - "T173791-", - "A173792-", - "A173793-", - "C173794-", - "T173795-", - "C173796-", - "C173797-", - "C173798-", - "A173799-", - "C173800-", - "A173801-", - "A173802-", - "T173803-", - "A173804-", - "C173805-", - "T173806-", - "A173807-", - "T173808-", - "A173809-", - "T173810-", - "A173811-", - "T173812-", - "A173813-", - "T173814-", - "T173815-", - "A173816-", - "T173817-", - "T173818-", - "A173819-", - "A173820-", - "T173821-", - "C173822-", - "A173823-", - "T173824-", - "T173825-", - "A173826-", - "A173827-", - "C173828-", - "T173829-", - "T173830-", - "G173831-", - "C173832-", - "A173833-", - "G173834-", - "A173835-", - "C173836-", - "T173837-", - "A173838-", - "T173839-", - "A173840-", - "C173841-", - "C173842-", - "T173843-", - "A173844-", - "G173845-", - "T173846-", - "A173847-", - "G173848-", - "T173849-", - "G173850-", - "C173851-", - "T173852-", - "A173853-", - "T173854-", - "T173855-", - "T173856-", - "T173857-", - "G173858-", - "A173859-", - "C173860-", - "A173861-", - "T173862-", - "A173863-", - "C173864-", - "T173865-", - "C173866-", - "A173867-", - "T173868-", - "G173869-", - "T173870-", - "T173871-", - "C173872-", - "T173873-", - "T173874-", - "G173875-", - "T173876-", - "G173877-", - "T173878-", - "A173879-", - "A173880-", - "T173881-", - "C173882-", - "G173883-", - "C173884-", - "A173885-", - "G173886-", - "T173887-", - "A173888-", - "T173889-", - "C173890-", - "T173891-", - "A173892-", - "T173893-", - "A173894-", - "T173895-", - "T173896-", - "A173897-", - "T173898-", - "T173899-", - "A173900-", - "A173901-", - "A173902-", - "G173903-", - "T173904-", - "A173905-", - "C173906-", - "G173907-", - "T173908-", - "A173909-", - "A173910-", - "A173911-", - "T173912-", - "C173913-", - "T173914-", - "A173915-", - "G173916-", - "C173917-", - "T173918-", - "A173919-", - "T173920-", - "A173921-", - "G173922-", - "T173923-", - "T173924-", - "T173925-", - "T173926-", - "A173927-", - "T173928-", - "T173929-", - "A173930-", - "T173931-", - "T173932-", - "T173933-", - "A173934-", - "A173935-", - "T173936-", - "T173937-", - "T173938-", - "T173939-", - "A173940-", - "G173941-", - "A173942-", - "T173943-", - "A173944-", - "A173945-", - "T173946-", - "A173947-", - "T173948-", - "A173949-", - "C173950-", - "T173951-", - "G173952-", - "T173953-", - "C173954-", - "T173955-", - "C173956-", - "C173957-", - "G173958-", - "T173959-", - "A173960-", - "T173961-", - "T173962-", - "T173963-", - "T173964-", - "T173965-", - "A173966-", - "A173967-", - "A173968-", - "A173969-", - "A173970-", - "A173971-", - "T173972-", - "T173973-", - "A173974-", - "C173975-", - "C173976-", - "A173977-", - "C173978-", - "A173979-", - "T173980-", - "C173981-", - "C173982-", - "T173983-", - "T173984-", - "T173985-", - "A173986-", - "T173987-", - "T173988-", - "A173989-", - "A173990-", - "A173991-", - "T173992-", - "C173993-", - "A173994-", - "T173995-", - "G173996-", - "A173997-", - "A173998-", - "T173999-", - "G174000-", - "G174001-", - "G174002-", - "A174003-", - "A174004-", - "T174005-", - "T174006-", - "T174007-", - "C174008-", - "T174009-", - "G174010-", - "T174011-", - "G174012-", - "T174013-", - "C174014-", - "A174015-", - "T174016-", - "C174017-", - "G174018-", - "T174019-", - "T174020-", - "A174021-", - "G174022-", - "T174023-", - "A174024-", - "T174025-", - "A174026-", - "T174027-", - "T174028-", - "G174029-", - "T174030-", - "G174031-", - "A174032-", - "A174033-", - "C174034-", - "A174035-", - "A174036-", - "C174037-", - "A174038-", - "A174039-", - "G174040-", - "A174041-", - "G174042-", - "C174043-", - "A174044-", - "G174045-", - "A174046-", - "T174047-", - "A174048-", - "T174049-", - "C174050-", - "T174051-", - "A174052-", - "T174053-", - "A174054-", - "G174055-", - "G174056-", - "A174057-", - "A174058-", - "A174059-", - "G174060-", - "G174061-", - "G174062-", - "T174063-", - "G174064-", - "G174065-", - "A174066-", - "A174067-", - "T174068-", - "G174069-", - "C174070-", - "G174071-", - "A174072-", - "T174073-", - "A174074-", - "C174075-", - "A174076-", - "T174077-", - "T174078-", - "G174079-", - "A174080-", - "T174081-", - "C174082-", - "T174083-", - "A174084-", - "T174085-", - "G174086-", - "T174087-", - "A174088-", - "G174089-", - "T174090-", - "T174091-", - "T174092-", - "T174093-", - "A174094-", - "A174095-", - "A174096-", - "A174097-", - "C174098-", - "A174099-", - "T174100-", - "A174101-", - "C174102-", - "G174103-", - "C174104-", - "G174105-", - "A174106-", - "A174107-", - "C174108-", - "T174109-", - "T174110-", - "T174111-", - "G174112-", - "A174113-", - "A174114-", - "G174115-", - "A174116-", - "A174117-", - "T174118-", - "T174119-", - "T174120-", - "A174121-", - "T174122-", - "A174123-", - "T174124-", - "A174125-", - "A174126-", - "A174127-", - "T174128-", - "C174129-", - "A174130-", - "T174131-", - "C174132-", - "T174133-", - "C174134-", - "A174135-", - "C174136-", - "G174137-", - "A174138-", - "G174139-", - "A174140-", - "T174141-", - "A174142-", - "T174143-", - "T174144-", - "G174145-", - "C174146-", - "T174147-", - "C174148-", - "T174149-", - "C174150-", - "T174151-", - "G174152-", - "T174153-", - "C174154-", - "A174155-", - "T174156-", - "A174157-", - "T174158-", - "T174159-", - "C174160-", - "A174161-", - "T174162-", - "A174163-", - "C174164-", - "A174165-", - "C174166-", - "C174167-", - "T174168-", - "G174169-", - "T174170-", - "A174171-", - "T174172-", - "A174173-", - "A174174-", - "A174175-", - "C174176-", - "T174177-", - "T174178-", - "T174179-", - "C174180-", - "T174181-", - "A174182-", - "G174183-", - "A174184-", - "C174185-", - "A174186-", - "T174187-", - "C174188-", - "T174189-", - "T174190-", - "A174191-", - "C174192-", - "A174193-", - "A174194-", - "T174195-", - "G174196-", - "T174197-", - "G174198-", - "T174199-", - "T174200-", - "A174201-", - "T174202-", - "T174203-", - "T174204-", - "T174205-", - "A174206-", - "T174207-", - "G174208-", - "A174209-", - "T174210-", - "C174211-", - "A174212-", - "T174213-", - "A174214-", - "T174215-", - "T174216-", - "T174217-", - "A174218-", - "C174219-", - "A174220-", - "T174221-", - "A174222-", - "T174223-", - "T174224-", - "T174225-", - "A174226-", - "C174227-", - "T174228-", - "G174229-", - "G174230-", - "T174231-", - "A174232-", - "T174233-", - "A174234-", - "T174235-", - "C174236-", - "A174237-", - "A174238-", - "A174239-", - "G174240-", - "A174241-", - "T174242-", - "G174243-", - "T174244-", - "T174245-", - "A174246-", - "G174247-", - "A174248-", - "T174249-", - "T174250-", - "A174251-", - "G174252-", - "T174253-", - "T174254-", - "A174255-", - "A174256-", - "T174257-", - "G174258-", - "G174259-", - "G174260-", - "A174261-", - "A174262-", - "T174263-", - "C174264-", - "G174265-", - "T174266-", - "C174267-", - "T174268-", - "A174269-", - "T174270-", - "A174271-", - "A174272-", - "T174273-", - "A174274-", - "A174275-", - "T174276-", - "G174277-", - "A174278-", - "A174279-", - "T174280-", - "A174281-", - "T174282-", - "T174283-", - "A174284-", - "A174285-", - "A174286-", - "C174287-", - "A174288-", - "A174289-", - "T174290-", - "T174291-", - "A174292-", - "T174293-", - "A174294-", - "G174295-", - "G174296-", - "A174297-", - "G174298-", - "G174299-", - "A174300-", - "G174301-", - "T174302-", - "T174303-", - "T174304-", - "A174305-", - "T174306-", - "A174307-", - "C174308-", - "C174309-", - "T174310-", - "A174311-", - "C174312-", - "A174313-", - "A174314-", - "A174315-", - "A174316-", - "A174317-", - "C174318-", - "A174319-", - "T174320-", - "C174321-", - "A174322-", - "T174323-", - "A174324-", - "A174325-", - "A174326-", - "A174327-", - "A174328-", - "T174329-", - "G174330-", - "A174331-", - "G174332-", - "T174333-", - "C174334-", - "A174335-", - "T174336-", - "C174337-", - "G174338-", - "T174339-", - "C174340-", - "C174341-", - "G174342-", - "A174343-", - "T174344-", - "T174345-", - "T174346-", - "A174347-", - "T174348-", - "G174349-", - "T174350-", - "T174351-", - "T174352-", - "T174353-", - "A174354-", - "A174355-", - "A174356-", - "T174357-", - "A174358-", - "T174359-", - "A174360-", - "C174361-", - "T174362-", - "A174363-", - "A174364-", - "C174365-", - "A174366-", - "T174367-", - "T174368-", - "A174369-", - "C174370-", - "T174371-", - "A174372-", - "C174373-", - "C174374-", - "T174375-", - "T174376-", - "C174377-", - "A174378-", - "G174379-", - "A174380-", - "A174381-", - "A174382-", - "T174383-", - "T174384-", - "A174385-", - "T174386-", - "A174387-", - "T174388-", - "A174389-", - "C174390-", - "G174391-", - "A174392-", - "A174393-", - "A174394-", - "T174395-", - "A174396-", - "T174397-", - "T174398-", - "A174399-", - "T174400-", - "A174401-", - "C174402-", - "A174403-", - "T174404-", - "G174405-", - "C174406-", - "T174407-", - "G174408-", - "A174409-", - "C174410-", - "A174411-", - "A174412-", - "T174413-", - "T174414-", - "A174415-", - "A174416-", - "C174417-", - "G174418-", - "A174419-", - "T174420-", - "C174421-", - "T174422-", - "T174423-", - "T174424-", - "A174425-", - "T174426-", - "A174427-", - "A174428-", - "T174429-", - "A174430-", - "T174431-", - "A174432-", - "T174433-", - "A174434-", - "G174435-", - "T174436-", - "A174437-", - "T174438-", - "C174439-", - "C174440-", - "A174441-", - "C174442-", - "C174443-", - "T174444-", - "A174445-", - "C174446-", - "C174447-", - "A174448-", - "A174449-", - "A174450-", - "G174451-", - "T174452-", - "A174453-", - "T174454-", - "A174455-", - "A174456-", - "T174457-", - "T174458-", - "G174459-", - "T174460-", - "A174461-", - "T174462-", - "T174463-", - "T174464-", - "T174465-", - "T174466-", - "C174467-", - "T174468-", - "C174469-", - "A174470-", - "T174471-", - "G174472-", - "T174473-", - "G174474-", - "A174475-", - "T174476-", - "G174477-", - "T174478-", - "G174479-", - "T174480-", - "G174481-", - "T174482-", - "A174483-", - "A174484-", - "A174485-", - "A174486-", - "A174487-", - "A174488-", - "C174489-", - "T174490-", - "G174491-", - "A174492-", - "T174493-", - "A174494-", - "T174495-", - "T174496-", - "A174497-", - "T174498-", - "A174499-", - "T174500-", - "A174501-", - "A174502-", - "T174503-", - "T174504-", - "A174505-", - "T174506-", - "C174507-", - "T174508-", - "T174509-", - "A174510-", - "G174511-", - "T174512-", - "A174513-", - "C174514-", - "C174515-", - "T174516-", - "A174517-", - "T174518-", - "G174519-", - "A174520-", - "T174521-", - "G174522-", - "A174523-", - "A174524-", - "G174525-", - "A174526-", - "T174527-", - "G174528-", - "A174529-", - "A174530-", - "G174531-", - "A174532-", - "T174533-", - "G174534-", - "A174535-", - "A174536-", - "G174537-", - "A174538-", - "T174539-", - "G174540-", - "A174541-", - "A174542-", - "G174543-", - "A174544-", - "T174545-", - "G174546-", - "A174547-", - "T174548-", - "G174549-", - "G174550-", - "T174551-", - "C174552-", - "C174553-", - "G174554-", - "T174555-", - "A174556-", - "T174557-", - "A174558-", - "T174559-", - "A174560-", - "T174561-", - "T174562-", - "T174563-", - "T174564-", - "G174565-", - "T174566-", - "A174567-", - "T174568-", - "C174569-", - "A174570-", - "T174571-", - "T174572-", - "A174573-", - "T174574-", - "C174575-", - "G174576-", - "T174577-", - "T174578-", - "A174579-", - "T174580-", - "T174581-", - "G174582-", - "C174583-", - "T174584-", - "A174585-", - "T174586-", - "T174587-", - "C174588-", - "C174589-", - "A174590-", - "T174591-", - "A174592-", - "G174593-", - "T174594-", - "T174595-", - "A174596-", - "C174597-", - "G174598-", - "C174599-", - "C174600-", - "A174601-", - "T174602-", - "A174603-", - "G174604-", - "A174605-", - "C174606-", - "A174607-", - "T174608-", - "C174609-", - "G174610-", - "A174611-", - "A174612-", - "A174613-", - "A174614-", - "T174615-", - "G174616-", - "A174617-", - "A174618-", - "A174619-", - "T174620-", - "C174621-", - "A174622-", - "C174623-", - "C174624-", - "G174625-", - "A174626-", - "A174627-", - "T174628-", - "T174629-", - "C174630-", - "T174631-", - "T174632-", - "C174633-", - "A174634-", - "A174635-", - "T174636-", - "A174637-", - "A174638-", - "A174639-", - "A174640-", - "T174641-", - "G174642-", - "A174643-", - "G174644-", - "A174645-", - "G174646-", - "A174647-", - "T174648-", - "A174649-", - "C174650-", - "T174651-", - "C174652-", - "T174653-", - "A174654-", - "C174655-", - "C174656-", - "A174657-", - "G174658-", - "C174659-", - "T174660-", - "A174661-", - "A174662-", - "A174663-", - "G174664-", - "A174665-", - "C174666-", - "T174667-", - "C174668-", - "T174669-", - "A174670-", - "A174671-", - "A174672-", - "T174673-", - "G174674-", - "G174675-", - "T174676-", - "T174677-", - "G174678-", - "A174679-", - "A174680-", - "T174681-", - "C174682-", - "C174683-", - "A174684-", - "G174685-", - "T174686-", - "A174687-", - "T174688-", - "G174689-", - "T174690-", - "A174691-", - "T174692-", - "G174693-", - "T174694-", - "T174695-", - "T174696-", - "G174697-", - "G174698-", - "A174699-", - "G174700-", - "G174701-", - "C174702-", - "A174703-", - "C174704-", - "A174705-", - "A174706-", - "T174707-", - "G174708-", - "A174709-", - "A174710-", - "T174711-", - "G174712-", - "A174713-", - "T174714-", - "A174715-", - "T174716-", - "G174717-", - "G174718-", - "C174719-", - "C174720-", - "G174721-", - "C174722-", - "T174723-", - "C174724-", - "T174725-", - "A174726-", - "G174727-", - "G174728-", - "A174729-", - "G174730-", - "A174731-", - "G174732-", - "C174733-", - "C174734-", - "A174735-", - "T174736-", - "T174737-", - "C174738-", - "A174739-", - "G174740-", - "T174741-", - "G174742-", - "C174743-", - "A174744-", - "A174745-", - "A174746-", - "G174747-", - "T174748-", - "G174749-", - "T174750-", - "C174751-", - "C174752-", - "T174753-", - "C174754-", - "C174755-", - "T174756-", - "A174757-", - "T174758-", - "T174759-", - "G174760-", - "A174761-", - "A174762-", - "G174763-", - "A174764-", - "C174765-", - "A174766-", - "G174767-", - "T174768-", - "C174769-", - "T174770-", - "T174771-", - "T174772-", - "T174773-", - "A174774-", - "T174775-", - "C174776-", - "G174777-", - "C174778-", - "A174779-", - "T174780-", - "A174781-", - "G174782-", - "A174783-", - "T174784-", - "A174785-", - "T174786-", - "A174787-", - "A174788-", - "A174789-", - "G174790-", - "A174791-", - "C174792-", - "T174793-", - "A174794-", - "T174795-", - "G174796-", - "T174797-", - "G174798-", - "G174799-", - "T174800-", - "T174801-", - "A174802-", - "A174803-", - "A174804-", - "T174805-", - "G174806-", - "G174807-", - "G174808-", - "A174809-", - "A174810-", - "A174811-", - "G174812-", - "G174813-", - "C174814-", - "T174815-", - "A174816-", - "G174817-", - "A174818-", - "A174819-", - "A174820-", - "A174821-", - "G174822-", - "A174823-", - "A174824-", - "T174825-", - "A174826-", - "G174827-", - "A174828-", - "C174829-", - "G174830-", - "G174831-", - "C174832-", - "G174833-", - "A174834-", - "C174835-", - "A174836-", - "G174837-", - "G174838-", - "T174839-", - "T174840-", - "T174841-", - "C174842-", - "T174843-", - "A174844-", - "A174845-", - "T174846-", - "A174847-", - "A174848-", - "A174849-", - "C174850-", - "G174851-", - "T174852-", - "G174853-", - "T174854-", - "T174855-", - "A174856-", - "A174857-", - "A174858-", - "C174859-", - "A174860-", - "T174861-", - "G174862-", - "G174863-", - "T174864-", - "G174865-", - "A174866-", - "T174867-", - "T174868-", - "T174869-", - "A174870-", - "T174871-", - "G174872-", - "G174873-", - "A174874-", - "T174875-", - "A174876-", - "G174877-", - "C174878-", - "C174879-", - "A174880-", - "A174881-", - "C174882-", - "T174883-", - "A174884-", - "T174885-", - "A174886-", - "C174887-", - "A174888-", - "T174889-", - "C174890-", - "T174891-", - "A174892-", - "A174893-", - "A174894-", - "T174895-", - "T174896-", - "C174897-", - "A174898-", - "G174899-", - "T174900-", - "A174901-", - "A174902-", - "C174903-", - "C174904-", - "G174905-", - "T174906-", - "A174907-", - "G174908-", - "G174909-", - "T174910-", - "A174911-", - "T174912-", - "T174913-", - "T174914-", - "A174915-", - "T174916-", - "G174917-", - "T174918-", - "A174919-", - "C174920-", - "C174921-", - "G174922-", - "T174923-", - "A174924-", - "A174925-", - "C174926-", - "C174927-", - "A174928-", - "C174929-", - "A174930-", - "A174931-", - "A174932-", - "G174933-", - "A174934-", - "A174935-", - "T174936-", - "G174937-", - "G174938-", - "T174939-", - "G174940-", - "A174941-", - "C174942-", - "T174943-", - "G174944-", - "T174945-", - "G174946-", - "T174947-", - "T174948-", - "C174949-", - "A174950-", - "G174951-", - "G174952-", - "G174953-", - "T174954-", - "G174955-", - "T174956-", - "A174957-", - "G174958-", - "T174959-", - "T174960-", - "A174961-", - "G174962-", - "A174963-", - "T174964-", - "C174965-", - "T174966-", - "C174967-", - "A174968-", - "T174969-", - "G174970-", - "T174971-", - "G174972-", - "T174973-", - "G174974-", - "G174975-", - "A174976-", - "A174977-", - "A174978-", - "C174979-", - "C174980-", - "T174981-", - "T174982-", - "C174983-", - "T174984-", - "T174985-", - "C174986-", - "A174987-", - "T174988-", - "G174989-", - "C174990-", - "A174991-", - "T174992-", - "T174993-", - "C174994-", - "C174995-", - "A174996-", - "A174997-", - "A174998-", - "A174999-", - "A175000-", - "C175001-", - "A175002-", - "T175003-", - "A175004-", - "T175005-", - "G175006-", - "A175007-", - "A175008-", - "C175009-", - "T175010-", - "A175011-", - "G175012-", - "G175013-", - "T175014-", - "A175015-", - "C175016-", - "T175017-", - "T175018-", - "A175019-", - "T175020-", - "G175021-", - "A175022-", - "T175023-", - "A175024-", - "A175025-", - "G175026-", - "T175027-", - "A175028-", - "T175029-", - "G175030-", - "G175031-", - "C175032-", - "A175033-", - "T175034-", - "A175035-", - "G175036-", - "A175037-", - "C175038-", - "T175039-", - "T175040-", - "A175041-", - "T175042-", - "A175043-", - "C175044-", - "T175045-", - "G175046-", - "T175047-", - "G175048-", - "G175049-", - "A175050-", - "A175051-", - "T175052-", - "T175053-", - "C175054-", - "T175055-", - "T175056-", - "T175057-", - "A175058-", - "T175059-", - "G175060-", - "C175061-", - "G175062-", - "A175063-", - "A175064-", - "C175065-", - "C175066-", - "A175067-", - "T175068-", - "T175069-", - "A175070-", - "T175071-", - "A175072-", - "A175073-", - "T175074-", - "A175075-", - "A175076-", - "T175077-", - "A175078-", - "T175079-", - "A175080-", - "A175081-", - "C175082-", - "T175083-", - "T175084-", - "G175085-", - "G175086-", - "T175087-", - "A175088-", - "T175089-", - "A175090-", - "A175091-", - "A175092-", - "G175093-", - "A175094-", - "T175095-", - "A175096-", - "A175097-", - "T175098-", - "A175099-", - "A175100-", - "G175101-", - "G175102-", - "A175103-", - "A175104-", - "A175105-", - "T175106-", - "T175107-", - "A175108-", - "A175109-", - "T175110-", - "A175111-", - "T175112-", - "C175113-", - "G175114-", - "A175115-", - "C175116-", - "G175117-", - "A175118-", - "T175119-", - "T175120-", - "T175121-", - "T175122-", - "A175123-", - "A175124-", - "G175125-", - "T175126-", - "A175127-", - "T175128-", - "T175129-", - "C175130-", - "A175131-", - "C175132-", - "A175133-", - "A175134-", - "G175135-", - "C175136-", - "G175137-", - "G175138-", - "G175139-", - "A175140-", - "A175141-", - "A175142-", - "G175143-", - "G175144-", - "A175145-", - "A175146-", - "T175147-", - "T175148-", - "A175149-", - "A175150-", - "T175151-", - "T175152-", - "A175153-", - "T175154-", - "T175155-", - "C175156-", - "A175157-", - "T175158-", - "A175159-", - "A175160-", - "T175161-", - "C175162-", - "C175163-", - "A175164-", - "G175165-", - "A175166-", - "G175167-", - "T175168-", - "T175169-", - "A175170-", - "G175171-", - "A175172-", - "A175173-", - "G175174-", - "A175175-", - "T175176-", - "A175177-", - "G175178-", - "T175179-", - "G175180-", - "G175181-", - "A175182-", - "A175183-", - "G175184-", - "A175185-", - "T175186-", - "A175187-", - "C175188-", - "G175189-", - "A175190-", - "C175191-", - "T175192-", - "G175193-", - "T175194-", - "T175195-", - "A175196-", - "C175197-", - "G175198-", - "T175199-", - "T175200-", - "C175201-", - "A175202-", - "T175203-", - "T175204-", - "A175205-", - "C175206-", - "G175207-", - "A175208-", - "C175209-", - "G175210-", - "A175211-", - "C175212-", - "G175213-", - "T175214-", - "T175215-", - "A175216-", - "G175217-", - "A175218-", - "A175219-", - "T175220-", - "C175221-", - "A175222-", - "A175223-", - "G175224-", - "A175225-", - "A175226-", - "T175227-", - "G175228-", - "A175229-", - "T175230-", - "A175231-", - "T175232-", - "C175233-", - "G175234-", - "T175235-", - "A175236-", - "G175237-", - "T175238-", - "A175239-", - "T175240-", - "C175241-", - "A175242-", - "A175243-", - "G175244-", - "A175245-", - "T175246-", - "G175247-", - "T175248-", - "A175249-", - "A175250-", - "A175251-", - "A175252-", - "T175253-", - "A175254-", - "C175255-", - "T175256-", - "T175257-", - "A175258-", - "C175259-", - "G175260-", - "G175261-", - "T175262-", - "T175263-", - "A175264-", - "T175265-", - "A175266-", - "C175267-", - "C175268-", - "G175269-", - "T175270-", - "C175271-", - "A175272-", - "C175273-", - "A175274-", - "A175275-", - "G175276-", - "A175277-", - "C175278-", - "C175279-", - "A175280-", - "C175281-", - "A175282-", - "G175283-", - "G175284-", - "T175285-", - "T175286-", - "T175287-", - "A175288-", - "A175289-", - "A175290-", - "C175291-", - "T175292-", - "A175293-", - "A175294-", - "T175295-", - "A175296-", - "C175297-", - "T175298-", - "A175299-", - "G175300-", - "A175301-", - "T175302-", - "C175303-", - "C175304-", - "G175305-", - "A175306-", - "A175307-", - "A175308-", - "A175309-", - "T175310-", - "C175311-", - "A175312-", - "A175313-", - "C175314-", - "G175315-", - "T175316-", - "A175317-", - "A175318-", - "C175319-", - "G175320-", - "A175321-", - "T175322-", - "A175323-", - "G175324-", - "G175325-", - "A175326-", - "G175327-", - "A175328-", - "A175329-", - "C175330-", - "C175331-", - "T175332-", - "G175333-", - "C175334-", - "C175335-", - "A175336-", - "A175337-", - "T175338-", - "A175339-", - "T175340-", - "A175341-", - "A175342-", - "C175343-", - "A175344-", - "T175345-", - "G175346-", - "C175347-", - "A175348-", - "G175349-", - "T175350-", - "G175351-", - "C175352-", - "T175353-", - "G175354-", - "T175355-", - "G175356-", - "T175357-", - "C175358-", - "A175359-", - "A175360-", - "C175361-", - "G175362-", - "T175363-", - "C175364-", - "A175365-", - "T175366-", - "T175367-", - "A175368-", - "T175369-", - "T175370-", - "T175371-", - "G175372-", - "T175373-", - "C175374-", - "G175375-", - "A175376-", - "C175377-", - "G175378-", - "A175379-", - "T175380-", - "G175381-", - "T175382-", - "A175383-", - "C175384-", - "T175385-", - "G175386-", - "A175387-", - "T175388-", - "T175389-", - "G175390-", - "A175391-", - "A175392-", - "T175393-", - "G175394-", - "G175395-", - "G175396-", - "A175397-", - "A175398-", - "A175399-", - "A175400-", - "T175401-", - "C175402-", - "C175403-", - "A175404-", - "T175405-", - "C175406-", - "C175407-", - "G175408-", - "G175409-", - "A175410-", - "T175411-", - "G175412-", - "G175413-", - "A175414-", - "T175415-", - "T175416-", - "A175417-", - "T175418-", - "A175419-", - "G175420-", - "G175421-", - "A175422-", - "T175423-", - "T175424-", - "A175425-", - "G175426-", - "A175427-", - "T175428-", - "T175429-", - "T175430-", - "T175431-", - "G175432-", - "G175433-", - "T175434-", - "G175435-", - "T175436-", - "A175437-", - "T175438-", - "A175439-", - "C175440-", - "T175441-", - "C175442-", - "T175443-", - "A175444-", - "T175445-", - "T175446-", - "T175447-", - "T175448-", - "A175449-", - "A175450-", - "C175451-", - "T175452-", - "A175453-", - "G175454-", - "T175455-", - "A175456-", - "G175457-", - "A175458-", - "G175459-", - "G175460-", - "C175461-", - "G175462-", - "G175463-", - "T175464-", - "A175465-", - "T175466-", - "C175467-", - "A175468-", - "C175469-", - "C175470-", - "G175471-", - "A175472-", - "G175473-", - "G175474-", - "C175475-", - "G175476-", - "A175477-", - "C175478-", - "T175479-", - "T175480-", - "T175481-", - "G175482-", - "T175483-", - "A175484-", - "T175485-", - "T175486-", - "T175487-", - "T175488-", - "G175489-", - "A175490-", - "A175491-", - "A175492-", - "A175493-", - "T175494-", - "G175495-", - "T175496-", - "T175497-", - "A175498-", - "C175499-", - "T175500-", - "G175501-", - "A175502-", - "A175503-", - "G175504-", - "A175505-", - "A175506-", - "T175507-", - "A175508-", - "T175509-", - "A175510-", - "T175511-", - "A175512-", - "G175513-", - "G175514-", - "C175515-", - "A175516-", - "A175517-", - "T175518-", - "A175519-", - "C175520-", - "A175521-", - "T175522-", - "A175523-", - "T175524-", - "A175525-", - "C175526-", - "A175527-", - "T175528-", - "G175529-", - "T175530-", - "C175531-", - "G175532-", - "T175533-", - "G175534-", - "G175535-", - "A175536-", - "C175537-", - "A175538-", - "C175539-", - "A175540-", - "A175541-", - "C175542-", - "T175543-", - "A175544-", - "T175545-", - "T175546-", - "A175547-", - "T175548-", - "T175549-", - "T175550-", - "T175551-", - "G175552-", - "A175553-", - "T175554-", - "A175555-", - "A175556-", - "A175557-", - "A175558-", - "C175559-", - "T175560-", - "C175561-", - "T175562-", - "T175563-", - "A175564-", - "C175565-", - "A175566-", - "A175567-", - "C175568-", - "T175569-", - "A175570-", - "C175571-", - "A175572-", - "G175573-", - "T175574-", - "A175575-", - "G175576-", - "T175577-", - "A175578-", - "T175579-", - "T175580-", - "G175581-", - "G175582-", - "A175583-", - "G175584-", - "T175585-", - "A175586-", - "A175587-", - "A175588-", - "T175589-", - "A175590-", - "C175591-", - "A175592-", - "C175593-", - "A175594-", - "A175595-", - "T175596-", - "G175597-", - "C175598-", - "A175599-", - "T175600-", - "T175601-", - "T175602-", - "T175603-", - "T175604-", - "A175605-", - "T175606-", - "A175607-", - "T175608-", - "A175609-", - "C175610-", - "A175611-", - "T175612-", - "T175613-", - "A175614-", - "C175615-", - "T175616-", - "G175617-", - "A175618-", - "A175619-", - "T175620-", - "T175621-", - "A175622-", - "T175623-", - "T175624-", - "A175625-", - "T175626-", - "T175627-", - "A175628-", - "T175629-", - "T175630-", - "A175631-", - "A175632-", - "T175633-", - "T175634-", - "A175635-", - "T175636-", - "A175637-", - "T175638-", - "C175639-", - "G175640-", - "T175641-", - "A175642-", - "T175643-", - "T175644-", - "T175645-", - "G175646-", - "T175647-", - "G175648-", - "C175649-", - "T175650-", - "A175651-", - "T175652-", - "A175653-", - "G175654-", - "A175655-", - "A175656-", - "T175657-", - "G175658-", - "G175659-", - "A175660-", - "T175661-", - "G175662-", - "A175663-", - "A175664-", - "G175665-", - "A175666-", - "T175667-", - "A175668-", - "C175669-", - "G175670-", - "C175671-", - "G175672-", - "A175673-", - "C175674-", - "T175675-", - "A175676-", - "T175677-", - "C175678-", - "T175679-", - "A175680-", - "G175681-", - "G175682-", - "T175683-", - "A175684-", - "T175685-", - "T175686-", - "T175687-", - "G175688-", - "T175689-", - "A175690-", - "T175691-", - "C175692-", - "T175693-", - "C175694-", - "A175695-", - "C175696-", - "C175697-", - "G175698-", - "A175699-", - "T175700-", - "A175701-", - "G175702-", - "A175703-", - "G175704-", - "A175705-", - "A175706-", - "C175707-", - "A175708-", - "T175709-", - "A175710-", - "T175711-", - "A175712-", - "A175713-", - "A175714-", - "T175715-", - "G175716-", - "T175717-", - "A175718-", - "G175719-", - "A175720-", - "C175721-", - "T175722-", - "C175723-", - "T175724-", - "A175725-", - "T175726-", - "T175727-", - "A175728-", - "A175729-", - "A175730-", - "C175731-", - "A175732-", - "G175733-", - "T175734-", - "T175735-", - "G175736-", - "T175737-", - "G175738-", - "T175739-", - "A175740-", - "A175741-", - "A175742-", - "A175743-", - "T175744-", - "A175745-", - "T175746-", - "C175747-", - "A175748-", - "G175749-", - "A175750-", - "T175751-", - "C175752-", - "C175753-", - "T175754-", - "A175755-", - "A175756-", - "T175757-", - "G175758-", - "C175759-", - "A175760-", - "T175761-", - "G175762-", - "T175763-", - "T175764-", - "A175765-", - "T175766-", - "A175767-", - "G175768-", - "A175769-", - "T175770-", - "G175771-", - "T175772-", - "G175773-", - "G175774-", - "A175775-", - "T175776-", - "G175777-", - "T175778-", - "A175779-", - "C175780-", - "G175781-", - "G175782-", - "C175783-", - "T175784-", - "T175785-", - "T175786-", - "A175787-", - "C175788-", - "A175789-", - "T175790-", - "G175791-", - "A175792-", - "G175793-", - "T175794-", - "A175795-", - "C175796-", - "T175797-", - "T175798-", - "T175799-", - "T175800-", - "A175801-", - "T175802-", - "A175803-", - "A175804-", - "T175805-", - "T175806-", - "A175807-", - "T175808-", - "A175809-", - "G175810-", - "A175811-", - "T175812-", - "C175813-", - "A175814-", - "G175815-", - "T175816-", - "C175817-", - "A175818-", - "A175819-", - "C175820-", - "G175821-", - "G175822-", - "A175823-", - "A175824-", - "A175825-", - "A175826-", - "T175827-", - "A175828-", - "C175829-", - "A175830-", - "A175831-", - "G175832-", - "T175833-", - "A175834-", - "T175835-", - "A175836-", - "G175837-", - "A175838-", - "T175839-", - "A175840-", - "C175841-", - "A175842-", - "A175843-", - "C175844-", - "G175845-", - "G175846-", - "T175847-", - "T175848-", - "A175849-", - "C175850-", - "T175851-", - "A175852-", - "T175853-", - "C175854-", - "A175855-", - "A175856-", - "T175857-", - "A175858-", - "T175859-", - "T175860-", - "A175861-", - "T175862-", - "T175863-", - "C175864-", - "A175865-", - "T175866-", - "C175867-", - "T175868-", - "A175869-", - "G175870-", - "C175871-", - "G175872-", - "A175873-", - "T175874-", - "T175875-", - "A175876-", - "T175877-", - "G175878-", - "A175879-", - "A175880-", - "A175881-", - "A175882-", - "T175883-", - "T175884-", - "A175885-", - "T175886-", - "A175887-", - "A175888-", - "T175889-", - "G175890-", - "A175891-", - "A175892-", - "T175893-", - "A175894-", - "T175895-", - "T175896-", - "A175897-", - "T175898-", - "T175899-", - "A175900-", - "T175901-", - "G175902-", - "A175903-", - "T175904-", - "G175905-", - "A175906-", - "T175907-", - "T175908-", - "A175909-", - "T175910-", - "G175911-", - "A175912-", - "T175913-", - "A175914-", - "G175915-", - "A175916-", - "A175917-", - "C175918-", - "T175919-", - "G175920-", - "G175921-", - "T175922-", - "A175923-", - "T175924-", - "G175925-", - "A175926-", - "A175927-", - "C175928-", - "A175929-", - "G175930-", - "T175931-", - "G175932-", - "A175933-", - "G175934-", - "A175935-", - "G175936-", - "T175937-", - "G175938-", - "A175939-", - "T175940-", - "A175941-", - "A175942-", - "T175943-", - "A175944-", - "T175945-", - "A175946-", - "T175947-", - "C175948-", - "A175949-", - "A175950-", - "T175951-", - "C175952-", - "A175953-", - "A175954-", - "A175955-", - "A175956-", - "C175957-", - "A175958-", - "G175959-", - "A175960-", - "A175961-", - "T175962-", - "A175963-", - "C175964-", - "G175965-", - "A175966-", - "G175967-", - "A175968-", - "A175969-", - "T175970-", - "G175971-", - "A175972-", - "A175973-", - "T175974-", - "A175975-", - "T175976-", - "G175977-", - "A175978-", - "A175979-", - "T175980-", - "T175981-", - "C175982-", - "T175983-", - "A175984-", - "T175985-", - "G175986-", - "A175987-", - "T175988-", - "G175989-", - "A175990-", - "A175991-", - "A175992-", - "C175993-", - "A175994-", - "C175995-", - "A175996-", - "A175997-", - "G175998-", - "A175999-", - "T176000-", - "C176001-", - "A176002-", - "A176003-", - "A176004-", - "G176005-", - "T176006-", - "A176007-", - "C176008-", - "A176009-", - "C176010-", - "A176011-", - "A176012-", - "C176013-", - "T176014-", - "A176015-", - "G176016-", - "T176017-", - "A176018-", - "G176019-", - "A176020-", - "T176021-", - "T176022-", - "A176023-", - "C176024-", - "G176025-", - "A176026-", - "C176027-", - "A176028-", - "T176029-", - "T176030-", - "A176031-", - "A176032-", - "A176033-", - "C176034-", - "T176035-", - "C176036-", - "A176037-", - "A176038-", - "A176039-", - "A176040-", - "C176041-", - "C176042-", - "A176043-", - "A176044-", - "T176045-", - "G176046-", - "A176047-", - "G176048-", - "G176049-", - "A176050-", - "T176051-", - "G176052-", - "A176053-", - "T176054-", - "T176055-", - "T176056-", - "T176057-", - "G176058-", - "T176059-", - "T176060-", - "G176061-", - "A176062-", - "T176063-", - "G176064-", - "A176065-", - "A176066-", - "T176067-", - "T176068-", - "C176069-", - "T176070-", - "A176071-", - "T176072-", - "G176073-", - "G176074-", - "T176075-", - "T176076-", - "A176077-", - "T176078-", - "G176079-", - "A176080-", - "T176081-", - "A176082-", - "G176083-", - "A176084-", - "T176085-", - "C176086-", - "A176087-", - "G176088-", - "T176089-", - "G176090-", - "G176091-", - "G176092-", - "T176093-", - "G176094-", - "T176095-", - "C176096-", - "C176097-", - "A176098-", - "T176099-", - "G176100-", - "A176101-", - "T176102-", - "T176103-", - "A176104-", - "T176105-", - "A176106-", - "T176107-", - "A176108-", - "G176109-", - "A176110-", - "T176111-", - "G176112-", - "T176113-", - "A176114-", - "T176115-", - "C176116-", - "A176117-", - "A176118-", - "T176119-", - "T176120-", - "A176121-", - "A176122-", - "T176123-", - "A176124-", - "A176125-", - "A176126-", - "G176127-", - "T176128-", - "A176129-", - "G176130-", - "T176131-", - "A176132-", - "T176133-", - "A176134-", - "T176135-", - "G176136-", - "G176137-", - "A176138-", - "A176139-", - "G176140-", - "A176141-", - "G176142-", - "A176143-", - "G176144-", - "T176145-", - "C176146-", - "T176147-", - "C176148-", - "A176149-", - "C176150-", - "G176151-", - "T176152-", - "A176153-", - "A176154-", - "G176155-", - "A176156-", - "T176157-", - "G176158-", - "G176159-", - "T176160-", - "G176161-", - "G176162-", - "G176163-", - "A176164-", - "T176165-", - "A176166-", - "T176167-", - "A176168-", - "T176169-", - "G176170-", - "G176171-", - "C176172-", - "A176173-", - "A176174-", - "G176175-", - "A176176-", - "A176177-", - "C176178-", - "A176179-", - "T176180-", - "A176181-", - "A176182-", - "T176183-", - "G176184-", - "A176185-", - "T176186-", - "G176187-", - "G176188-", - "C176189-", - "G176190-", - "T176191-", - "A176192-", - "T176193-", - "A176194-", - "C176195-", - "A176196-", - "G176197-", - "T176198-", - "A176199-", - "T176200-", - "A176201-", - "G176202-", - "G176203-", - "A176204-", - "A176205-", - "A176206-", - "G176207-", - "G176208-", - "A176209-", - "G176210-", - "T176211-", - "G176212-", - "C176213-", - "A176214-", - "T176215-", - "A176216-", - "G176217-", - "A176218-", - "T176219-", - "A176220-", - "A176221-", - "T176222-", - "A176223-", - "T176224-", - "A176225-", - "T176226-", - "A176227-", - "C176228-", - "G176229-", - "A176230-", - "A176231-", - "G176232-", - "A176233-", - "C176234-", - "A176235-", - "G176236-", - "A176237-", - "C176238-", - "A176239-", - "T176240-", - "A176241-", - "C176242-", - "C176243-", - "G176244-", - "T176245-", - "A176246-", - "G176247-", - "A176248-", - "C176249-", - "G176250-", - "A176251-", - "A176252-", - "T176253-", - "T176254-", - "C176255-", - "T176256-", - "A176257-", - "C176258-", - "A176259-", - "A176260-", - "G176261-", - "A176262-", - "T176263-", - "A176264-", - "G176265-", - "A176266-", - "C176267-", - "A176268-", - "G176269-", - "C176270-", - "G176271-", - "T176272-", - "A176273-", - "T176274-", - "C176275-", - "A176276-", - "G176277-", - "A176278-", - "T176279-", - "G176280-", - "T176281-", - "A176282-", - "G176283-", - "A176284-", - "T176285-", - "G176286-", - "A176287-", - "C176288-", - "G176289-", - "C176290-", - "A176291-", - "G176292-", - "A176293-", - "A176294-", - "C176295-", - "A176296-", - "T176297-", - "A176298-", - "T176299-", - "A176300-", - "T176301-", - "C176302-", - "T176303-", - "C176304-", - "A176305-", - "G176306-", - "A176307-", - "T176308-", - "A176309-", - "A176310-", - "C176311-", - "T176312-", - "A176313-", - "A176314-", - "T176315-", - "G176316-", - "A176317-", - "T176318-", - "G176319-", - "T176320-", - "A176321-", - "T176322-", - "C176323-", - "T176324-", - "A176325-", - "C176326-", - "A176327-", - "C176328-", - "A176329-", - "A176330-", - "A176331-", - "C176332-", - "A176333-", - "T176334-", - "G176335-", - "G176336-", - "G176337-", - "A176338-", - "A176339-", - "A176340-", - "A176341-", - "G176342-", - "A176343-", - "A176344-", - "A176345-", - "T176346-", - "C176347-", - "A176348-", - "G176349-", - "A176350-", - "G176351-", - "T176352-", - "T176353-", - "A176354-", - "G176355-", - "A176356-", - "T176357-", - "A176358-", - "G176359-", - "A176360-", - "T176361-", - "A176362-", - "C176363-", - "A176364-", - "T176365-", - "G176366-", - "G176367-", - "A176368-", - "A176369-", - "A176370-", - "T176371-", - "G176372-", - "T176373-", - "A176374-", - "T176375-", - "C176376-", - "C176377-", - "T176378-", - "C176379-", - "G176380-", - "T176381-", - "C176382-", - "A176383-", - "T176384-", - "A176385-", - "G176386-", - "A176387-", - "T176388-", - "A176389-", - "T176390-", - "G176391-", - "G176392-", - "T176393-", - "A176394-", - "A176395-", - "G176396-", - "C176397-", - "A176398-", - "T176399-", - "T176400-", - "C176401-", - "T176402-", - "G176403-", - "T176404-", - "C176405-", - "T176406-", - "T176407-", - "T176408-", - "A176409-", - "A176410-", - "G176411-", - "G176412-", - "G176413-", - "A176414-", - "T176415-", - "T176416-", - "T176417-", - "T176418-", - "C176419-", - "T176420-", - "G176421-", - "A176422-", - "C176423-", - "A176424-", - "A176425-", - "A176426-", - "G176427-", - "T176428-", - "T176429-", - "A176430-", - "G176431-", - "A176432-", - "A176433-", - "A176434-", - "A176435-", - "A176436-", - "A176437-", - "T176438-", - "G176439-", - "A176440-", - "T176441-", - "T176442-", - "T176443-", - "A176444-", - "G176445-", - "A176446-", - "C176447-", - "A176448-", - "T176449-", - "G176450-", - "A176451-", - "A176452-", - "C176453-", - "G176454-", - "T176455-", - "G176456-", - "G176457-", - "T176458-", - "A176459-", - "A176460-", - "A176461-", - "A176462-", - "G176463-", - "A176464-", - "A176465-", - "T176466-", - "T176467-", - "A176468-", - "C176469-", - "T176470-", - "T176471-", - "T176472-", - "C176473-", - "T176474-", - "A176475-", - "A176476-", - "C176477-", - "G176478-", - "G176479-", - "T176480-", - "G176481-", - "C176482-", - "A176483-", - "T176484-", - "C176485-", - "T176486-", - "C176487-", - "T176488-", - "A176489-", - "A176490-", - "C176491-", - "A176492-", - "A176493-", - "T176494-", - "C176495-", - "A176496-", - "A176497-", - "G176498-", - "G176499-", - "A176500-", - "T176501-", - "A176502-", - "G176503-", - "C176504-", - "A176505-", - "G176506-", - "T176507-", - "A176508-", - "A176509-", - "T176510-", - "A176511-", - "A176512-", - "G176513-", - "G176514-", - "A176515-", - "T176516-", - "C176517-", - "C176518-", - "A176519-", - "A176520-", - "T176521-", - "T176522-", - "G176523-", - "C176524-", - "T176525-", - "G176526-", - "T176527-", - "T176528-", - "T176529-", - "A176530-", - "T176531-", - "T176532-", - "T176533-", - "T176534-", - "A176535-", - "G176536-", - "A176537-", - "A176538-", - "G176539-", - "A176540-", - "A176541-", - "C176542-", - "A176543-", - "A176544-", - "T176545-", - "A176546-", - "A176547-", - "T176548-", - "G176549-", - "A176550-", - "A176551-", - "T176552-", - "T176553-", - "T176554-", - "A176555-", - "G176556-", - "A176557-", - "A176558-", - "A176559-", - "T176560-", - "G176561-", - "A176562-", - "T176563-", - "T176564-", - "G176565-", - "A176566-", - "T176567-", - "A176568-", - "T176569-", - "C176570-", - "A176571-", - "T176572-", - "T176573-", - "A176574-", - "A176575-", - "C176576-", - "A176577-", - "A176578-", - "A176579-", - "C176580-", - "A176581-", - "T176582-", - "A176583-", - "C176584-", - "A176585-", - "A176586-", - "C176587-", - "T176588-", - "A176589-", - "T176590-", - "C176591-", - "T176592-", - "A176593-", - "T176594-", - "G176595-", - "A176596-", - "A176597-", - "C176598-", - "G176599-", - "C176600-", - "A176601-", - "G176602-", - "G176603-", - "T176604-", - "A176605-", - "T176606-", - "A176607-", - "T176608-", - "A176609-", - "G176610-", - "T176611-", - "A176612-", - "C176613-", - "A176614-", - "C176615-", - "T176616-", - "C176617-", - "C176618-", - "T176619-", - "A176620-", - "T176621-", - "C176622-", - "T176623-", - "A176624-", - "A176625-", - "A176626-", - "A176627-", - "A176628-", - "A176629-", - "T176630-", - "T176631-", - "A176632-", - "T176633-", - "A176634-", - "G176635-", - "A176636-", - "A176637-", - "A176638-", - "T176639-", - "T176640-", - "T176641-", - "C176642-", - "G176643-", - "A176644-", - "T176645-", - "T176646-", - "A176647-", - "T176648-", - "C176649-", - "C176650-", - "A176651-", - "T176652-", - "T176653-", - "T176654-", - "T176655-", - "T176656-", - "C176657-", - "A176658-", - "G176659-", - "A176660-", - "A176661-", - "A176662-", - "G176663-", - "T176664-", - "T176665-", - "A176666-", - "G176667-", - "T176668-", - "T176669-", - "T176670-", - "T176671-", - "G176672-", - "A176673-", - "C176674-", - "T176675-", - "A176676-", - "A176677-", - "T176678-", - "A176679-", - "A176680-", - "A176681-", - "C176682-", - "A176683-", - "T176684-", - "T176685-", - "G176686-", - "T176687-", - "C176688-", - "T176689-", - "C176690-", - "A176691-", - "A176692-", - "C176693-", - "A176694-", - "A176695-", - "T176696-", - "T176697-", - "A176698-", - "T176699-", - "T176700-", - "G176701-", - "T176702-", - "A176703-", - "A176704-", - "T176705-", - "A176706-", - "T176707-", - "A176708-", - "A176709-", - "G176710-", - "C176711-", - "G176712-", - "A176713-", - "C176714-", - "G176715-", - "G176716-", - "C176717-", - "A176718-", - "A176719-", - "A176720-", - "T176721-", - "A176722-", - "T176723-", - "G176724-", - "G176725-", - "A176726-", - "A176727-", - "C176728-", - "A176729-", - "C176730-", - "C176731-", - "A176732-", - "C176733-", - "T176734-", - "A176735-", - "C176736-", - "A176737-", - "T176738-", - "A176739-", - "T176740-", - "A176741-", - "T176742-", - "T176743-", - "A176744-", - "G176745-", - "C176746-", - "A176747-", - "T176748-", - "C176749-", - "T176750-", - "A176751-", - "A176752-", - "T176753-", - "A176754-", - "A176755-", - "A176756-", - "A176757-", - "A176758-", - "A176759-", - "A176760-", - "T176761-", - "A176762-", - "A176763-", - "T176764-", - "A176765-", - "A176766-", - "C176767-", - "T176768-", - "C176769-", - "C176770-", - "T176771-", - "A176772-", - "A176773-", - "T176774-", - "T176775-", - "A176776-", - "C176777-", - "A176778-", - "T176779-", - "G176780-", - "A176781-", - "A176782-", - "G176783-", - "T176784-", - "T176785-", - "A176786-", - "T176787-", - "T176788-", - "A176789-", - "G176790-", - "T176791-", - "G176792-", - "T176793-", - "A176794-", - "T176795-", - "A176796-", - "A176797-", - "C176798-", - "G176799-", - "G176800-", - "A176801-", - "A176802-", - "A176803-", - "T176804-", - "G176805-", - "A176806-", - "T176807-", - "A176808-", - "T176809-", - "A176810-", - "A176811-", - "A176812-", - "C176813-", - "G176814-", - "C176815-", - "A176816-", - "C176817-", - "G176818-", - "A176819-", - "G176820-", - "G176821-", - "T176822-", - "G176823-", - "A176824-", - "A176825-", - "G176826-", - "A176827-", - "T176828-", - "A176829-", - "C176830-", - "A176831-", - "C176832-", - "A176833-", - "A176834-", - "A176835-", - "T176836-", - "G176837-", - "C176838-", - "G176839-", - "A176840-", - "A176841-", - "C176842-", - "T176843-", - "C176844-", - "C176845-", - "A176846-", - "T176847-", - "T176848-", - "A176849-", - "C176850-", - "A176851-", - "C176852-", - "A176853-", - "A176854-", - "A176855-", - "T176856-", - "A176857-", - "T176858-", - "T176859-", - "T176860-", - "G176861-", - "T176862-", - "G176863-", - "T176864-", - "A176865-", - "A176866-", - "A176867-", - "T176868-", - "T176869-", - "T176870-", - "G176871-", - "T176872-", - "A176873-", - "T176874-", - "A176875-", - "T176876-", - "C176877-", - "A176878-", - "T176879-", - "A176880-", - "A176881-", - "T176882-", - "A176883-", - "T176884-", - "T176885-", - "G176886-", - "A176887-", - "A176888-", - "T176889-", - "A176890-", - "T176891-", - "G176892-", - "G176893-", - "T176894-", - "A176895-", - "T176896-", - "C176897-", - "C176898-", - "G176899-", - "A176900-", - "T176901-", - "A176902-", - "C176903-", - "T176904-", - "A176905-", - "T176906-", - "A176907-", - "A176908-", - "T176909-", - "G176910-", - "A176911-", - "A176912-", - "A176913-", - "A176914-", - "G176915-", - "A176916-", - "T176917-", - "T176918-", - "A176919-", - "T176920-", - "A176921-", - "G176922-", - "A176923-", - "C176924-", - "G176925-", - "C176926-", - "A176927-", - "T176928-", - "T176929-", - "T176930-", - "A176931-", - "T176932-", - "A176933-", - "G176934-", - "A176935-", - "G176936-", - "T176937-", - "T176938-", - "A176939-", - "G176940-", - "G176941-", - "A176942-", - "G176943-", - "C176944-", - "C176945-", - "G176946-", - "A176947-", - "T176948-", - "C176949-", - "T176950-", - "A176951-", - "A176952-", - "C176953-", - "T176954-", - "A176955-", - "T176956-", - "T176957-", - "C176958-", - "C176959-", - "A176960-", - "A176961-", - "A176962-", - "T176963-", - "G176964-", - "A176965-", - "C176966-", - "G176967-", - "A176968-", - "T176969-", - "G176970-", - "G176971-", - "A176972-", - "A176973-", - "T176974-", - "G176975-", - "A176976-", - "T176977-", - "A176978-", - "C176979-", - "C176980-", - "A176981-", - "G176982-", - "T176983-", - "A176984-", - "G176985-", - "T176986-", - "T176987-", - "T176988-", - "A176989-", - "C176990-", - "T176991-", - "G176992-", - "T176993-", - "A176994-", - "T176995-", - "A176996-", - "C176997-", - "A176998-", - "C176999-", - "T177000-", - "C177001-", - "A177002-", - "A177003-", - "A177004-", - "T177005-", - "G177006-", - "C177007-", - "C177008-", - "G177009-", - "A177010-", - "A177011-", - "T177012-", - "A177013-", - "T177014-", - "G177015-", - "G177016-", - "T177017-", - "T177018-", - "A177019-", - "T177020-", - "A177021-", - "A177022-", - "C177023-", - "A177024-", - "A177025-", - "T177026-", - "A177027-", - "T177028-", - "T177029-", - "A177030-", - "C177031-", - "T177032-", - "A177033-", - "A177034-", - "C177035-", - "A177036-", - "T177037-", - "A177038-", - "A177039-", - "A177040-", - "G177041-", - "A177042-", - "T177043-", - "A177044-", - "A177045-", - "T177046-", - "A177047-", - "C177048-", - "G177049-", - "T177050-", - "A177051-", - "A177052-", - "A177053-", - "C177054-", - "T177055-", - "A177056-", - "C177057-", - "T177058-", - "T177059-", - "A177060-", - "A177061-", - "T177062-", - "C177063-", - "T177064-", - "T177065-", - "A177066-", - "G177067-", - "T177068-", - "A177069-", - "G177070-", - "A177071-", - "C177072-", - "A177073-", - "T177074-", - "G177075-", - "C177076-", - "G177077-", - "T177078-", - "C177079-", - "A177080-", - "C177081-", - "A177082-", - "T177083-", - "A177084-", - "A177085-", - "T177086-", - "C177087-", - "T177088-", - "A177089-", - "T177090-", - "T177091-", - "T177092-", - "A177093-", - "G177094-", - "A177095-", - "G177096-", - "A177097-", - "T177098-", - "C177099-", - "G177100-", - "A177101-", - "G177102-", - "T177103-", - "C177104-", - "A177105-", - "T177106-", - "G177107-", - "C177108-", - "A177109-", - "C177110-", - "G177111-", - "A177112-", - "T177113-", - "T177114-", - "A177115-", - "T177116-", - "A177117-", - "T177118-", - "A177119-", - "A177120-", - "G177121-", - "T177122-", - "A177123-", - "A177124-", - "T177125-", - "A177126-", - "C177127-", - "A177128-", - "T177129-", - "A177130-", - "T177131-", - "A177132-", - "T177133-", - "T177134-", - "G177135-", - "A177136-", - "T177137-", - "C177138-", - "T177139-", - "T177140-", - "G177141-", - "A177142-", - "G177143-", - "T177144-", - "G177145-", - "T177146-", - "T177147-", - "T177148-", - "A177149-", - "G177150-", - "A177151-", - "T177152-", - "A177153-", - "T177154-", - "C177155-", - "A177156-", - "T177157-", - "T177158-", - "A177159-", - "G177160-", - "A177161-", - "T177162-", - "C177163-", - "A177164-", - "C177165-", - "T177166-", - "T177167-", - "G177168-", - "A177169-", - "T177170-", - "G177171-", - "G177172-", - "G177173-", - "T177174-", - "A177175-", - "C177176-", - "G177177-", - "A177178-", - "T177179-", - "A177180-", - "T177181-", - "T177182-", - "A177183-", - "A177184-", - "T177185-", - "T177186-", - "G177187-", - "T177188-", - "T177189-", - "A177190-", - "C177191-", - "T177192-", - "T177193-", - "T177194-", - "G177195-", - "A177196-", - "A177197-", - "G177198-", - "G177199-", - "A177200-", - "C177201-", - "G177202-", - "T177203-", - "A177204-", - "C177205-", - "A177206-", - "C177207-", - "C177208-", - "A177209-", - "C177210-", - "T177211-", - "T177212-", - "C177213-", - "A177214-", - "T177215-", - "T177216-", - "G177217-", - "C177218-", - "G177219-", - "C177220-", - "T177221-", - "A177222-", - "T177223-", - "A177224-", - "C177225-", - "A177226-", - "A177227-", - "T177228-", - "A177229-", - "T177230-", - "A177231-", - "A177232-", - "C177233-", - "T177234-", - "T177235-", - "C177236-", - "A177237-", - "C177238-", - "T177239-", - "C177240-", - "A177241-", - "G177242-", - "A177243-", - "T177244-", - "T177245-", - "G177246-", - "C177247-", - "T177248-", - "G177249-", - "A177250-", - "G177251-", - "T177252-", - "A177253-", - "C177254-", - "T177255-", - "T177256-", - "A177257-", - "T177258-", - "T177259-", - "A177260-", - "G177261-", - "A177262-", - "T177263-", - "C177264-", - "G177265-", - "A177266-", - "G177267-", - "G177268-", - "A177269-", - "G177270-", - "C177271-", - "T177272-", - "G177273-", - "A177274-", - "T177275-", - "A177276-", - "T177277-", - "A177278-", - "T177279-", - "C177280-", - "A177281-", - "T177282-", - "T177283-", - "A177284-", - "A177285-", - "A177286-", - "G177287-", - "A177288-", - "C177289-", - "A177290-", - "G177291-", - "A177292-", - "C177293-", - "G177294-", - "A177295-", - "T177296-", - "G177297-", - "G177298-", - "T177299-", - "A177300-", - "A177301-", - "A177302-", - "A177303-", - "C177304-", - "T177305-", - "G177306-", - "T177307-", - "A177308-", - "T177309-", - "T177310-", - "T177311-", - "G177312-", - "A177313-", - "T177314-", - "T177315-", - "T177316-", - "A177317-", - "T177318-", - "C177319-", - "G177320-", - "T177321-", - "T177322-", - "A177323-", - "T177324-", - "G177325-", - "T177326-", - "A177327-", - "G177328-", - "T177329-", - "T177330-", - "A177331-", - "C177332-", - "A177333-", - "T177334-", - "T177335-", - "C177336-", - "C177337-", - "T177338-", - "C177339-", - "T177340-", - "T177341-", - "A177342-", - "A177343-", - "A177344-", - "T177345-", - "G177346-", - "G177347-", - "A177348-", - "C177349-", - "T177350-", - "A177351-", - "G177352-", - "C177353-", - "T177354-", - "T177355-", - "T177356-", - "T177357-", - "T177358-", - "G177359-", - "A177360-", - "T177361-", - "T177362-", - "A177363-", - "G177364-", - "T177365-", - "C177366-", - "G177367-", - "T177368-", - "C177369-", - "T177370-", - "A177371-", - "C177372-", - "C177373-", - "G177374-", - "C177375-", - "C177376-", - "T177377-", - "A177378-", - "A177379-", - "A177380-", - "A177381-", - "G177382-", - "T177383-", - "G177384-", - "T177385-", - "C177386-", - "A177387-", - "T177388-", - "A177389-", - "T177390-", - "G177391-", - "C177392-", - "T177393-", - "C177394-", - "A177395-", - "C177396-", - "T177397-", - "G177398-", - "A177399-", - "C177400-", - "T177401-", - "A177402-", - "A177403-", - "C177404-", - "C177405-", - "A177406-", - "T177407-", - "A177408-", - "T177409-", - "A177410-", - "A177411-", - "T177412-", - "A177413-", - "G177414-", - "A177415-", - "T177416-", - "T177417-", - "A177418-", - "T177419-", - "G177420-", - "T177421-", - "T177422-", - "C177423-", - "T177424-", - "T177425-", - "A177426-", - "C177427-", - "G177428-", - "A177429-", - "A177430-", - "C177431-", - "A177432-", - "A177433-", - "T177434-", - "A177435-", - "G177436-", - "A177437-", - "C177438-", - "G177439-", - "T177440-", - "A177441-", - "T177442-", - "T177443-", - "A177444-", - "T177445-", - "T177446-", - "T177447-", - "G177448-", - "G177449-", - "C177450-", - "A177451-", - "G177452-", - "A177453-", - "G177454-", - "T177455-", - "C177456-", - "A177457-", - "A177458-", - "A177459-", - "T177460-", - "G177461-", - "A177462-", - "T177463-", - "T177464-", - "A177465-", - "A177466-", - "T177467-", - "A177468-", - "A177469-", - "G177470-", - "T177471-", - "A177472-", - "C177473-", - "G177474-", - "T177475-", - "A177476-", - "C177477-", - "T177478-", - "G177479-", - "T177480-", - "T177481-", - "A177482-", - "C177483-", - "T177484-", - "G177485-", - "G177486-", - "A177487-", - "C177488-", - "C177489-", - "C177490-", - "A177491-", - "T177492-", - "C177493-", - "C177494-", - "T177495-", - "T177496-", - "T177497-", - "T177498-", - "A177499-", - "T177500-", - "T177501-", - "A177502-", - "T177503-", - "A177504-", - "G177505-", - "A177506-", - "T177507-", - "T177508-", - "C177509-", - "A177510-", - "G177511-", - "A177512-", - "A177513-", - "A177514-", - "T177515-", - "G177516-", - "T177517-", - "T177518-", - "A177519-", - "T177520-", - "C177521-", - "G177522-", - "A177523-", - "A177524-", - "A177525-", - "A177526-", - "C177527-", - "A177528-", - "A177529-", - "A177530-", - "T177531-", - "T177532-", - "A177533-", - "G177534-", - "A177535-", - "C177536-", - "C177537-", - "A177538-", - "A177539-", - "T177540-", - "A177541-", - "C177542-", - "A177543-", - "A177544-", - "T177545-", - "A177546-", - "A177547-", - "T177548-", - "C177549-", - "G177550-", - "T177551-", - "T177552-", - "A177553-", - "T177554-", - "A177555-", - "A177556-", - "T177557-", - "A177558-", - "T177559-", - "G177560-", - "T177561-", - "T177562-", - "C177563-", - "G177564-", - "A177565-", - "A177566-", - "C177567-", - "A177568-", - "C177569-", - "G177570-", - "A177571-", - "T177572-", - "A177573-", - "G177574-", - "G177575-", - "G177576-", - "A177577-", - "C177578-", - "G177579-", - "T177580-", - "T177581-", - "A177582-", - "A177583-", - "T177584-", - "G177585-", - "A177586-", - "A177587-", - "A177588-", - "A177589-", - "G177590-", - "T177591-", - "A177592-", - "T177593-", - "G177594-", - "G177595-", - "C177596-", - "A177597-", - "A177598-", - "A177599-", - "G177600-", - "T177601-", - "C177602-", - "T177603-", - "T177604-", - "A177605-", - "C177606-", - "A177607-", - "T177608-", - "G177609-", - "A177610-", - "C177611-", - "C177612-", - "T177613-", - "C177614-", - "G177615-", - "A177616-", - "T177617-", - "A177618-", - "C177619-", - "A177620-", - "T177621-", - "A177622-", - "T177623-", - "A177624-", - "T177625-", - "C177626-", - "A177627-", - "A177628-", - "G177629-", - "G177630-", - "A177631-", - "T177632-", - "G177633-", - "T177634-", - "A177635-", - "C177636-", - "A177637-", - "A177638-", - "G177639-", - "T177640-", - "A177641-", - "T177642-", - "T177643-", - "A177644-", - "A177645-", - "A177646-", - "A177647-", - "T177648-", - "C177649-", - "T177650-", - "A177651-", - "C177652-", - "T177653-", - "T177654-", - "C177655-", - "C177656-", - "A177657-", - "T177658-", - "C177659-", - "A177660-", - "C177661-", - "T177662-", - "A177663-", - "A177664-", - "T177665-", - "A177666-", - "A177667-", - "T177668-", - "A177669-", - "T177670-", - "A177671-", - "A177672-", - "C177673-", - "A177674-", - "C177675-", - "T177676-", - "A177677-", - "T177678-", - "A177679-", - "C177680-", - "G177681-", - "A177682-", - "C177683-", - "A177684-", - "C177685-", - "T177686-", - "A177687-", - "T177688-", - "T177689-", - "A177690-", - "T177691-", - "A177692-", - "A177693-", - "A177694-", - "T177695-", - "A177696-", - "A177697-", - "T177698-", - "A177699-", - "A177700-", - "G177701-", - "T177702-", - "C177703-", - "A177704-", - "G177705-", - "A177706-", - "G177707-", - "T177708-", - "T177709-", - "T177710-", - "C177711-", - "C177712-", - "T177713-", - "A177714-", - "T177715-", - "A177716-", - "C177717-", - "G177718-", - "T177719-", - "C177720-", - "G177721-", - "T177722-", - "G177723-", - "T177724-", - "A177725-", - "A177726-", - "A177727-", - "C177728-", - "G177729-", - "A177730-", - "C177731-", - "A177732-", - "A177733-", - "A177734-", - "C177735-", - "A177736-", - "A177737-", - "T177738-", - "T177739-", - "A177740-", - "A177741-", - "T177742-", - "T177743-", - "A177744-", - "A177745-", - "T177746-", - "C177747-", - "T177748-", - "C177749-", - "A177750-", - "T177751-", - "A177752-", - "A177753-", - "A177754-", - "A177755-", - "T177756-", - "C177757-", - "C177758-", - "A177759-", - "A177760-", - "T177761-", - "A177762-", - "C177763-", - "A177764-", - "T177765-", - "A177766-", - "T177767-", - "C177768-", - "A177769-", - "T177770-", - "A177771-", - "A177772-", - "T177773-", - "C177774-", - "T177775-", - "T177776-", - "A177777-", - "T177778-", - "C177779-", - "G177780-", - "A177781-", - "A177782-", - "A177783-", - "A177784-", - "A177785-", - "G177786-", - "T177787-", - "T177788-", - "A177789-", - "T177790-", - "T177791-", - "A177792-", - "A177793-", - "A177794-", - "A177795-", - "A177796-", - "T177797-", - "A177798-", - "C177799-", - "A177800-", - "T177801-", - "T177802-", - "A177803-", - "G177804-", - "A177805-", - "G177806-", - "A177807-", - "A177808-", - "A177809-", - "T177810-", - "A177811-", - "T177812-", - "A177813-", - "C177814-", - "T177815-", - "T177816-", - "T177817-", - "A177818-", - "A177819-", - "C177820-", - "T177821-", - "A177822-", - "A177823-", - "T177824-", - "A177825-", - "T177826-", - "A177827-", - "G177828-", - "T177829-", - "C177830-", - "C177831-", - "T177832-", - "C177833-", - "G177834-", - "A177835-", - "G177836-", - "T177837-", - "A177838-", - "T177839-", - "A177840-", - "T177841-", - "G177842-", - "A177843-", - "T177844-", - "C177845-", - "T177846-", - "C177847-", - "A177848-", - "T177849-", - "C177850-", - "T177851-", - "C177852-", - "G177853-", - "A177854-", - "T177855-", - "C177856-", - "T177857-", - "C177858-", - "A177859-", - "A177860-", - "T177861-", - "C177862-", - "A177863-", - "T177864-", - "C177865-", - "T177866-", - "T177867-", - "A177868-", - "T177869-", - "T177870-", - "T177871-", - "G177872-", - "A177873-", - "G177874-", - "T177875-", - "C177876-", - "G177877-", - "T177878-", - "A177879-", - "T177880-", - "T177881-", - "C177882-", - "C177883-", - "T177884-", - "A177885-", - "A177886-", - "T177887-", - "G177888-", - "A177889-", - "G177890-", - "A177891-", - "T177892-", - "A177893-", - "T177894-", - "T177895-", - "A177896-", - "C177897-", - "T177898-", - "C177899-", - "G177900-", - "A177901-", - "A177902-", - "A177903-", - "T177904-", - "A177905-", - "T177906-", - "T177907-", - "A177908-", - "T177909-", - "A177910-", - "T177911-", - "A177912-", - "A177913-", - "A177914-", - "C177915-", - "T177916-", - "C177917-", - "G177918-", - "A177919-", - "C177920-", - "A177921-", - "T177922-", - "G177923-", - "T177924-", - "A177925-", - "C177926-", - "G177927-", - "A177928-", - "T177929-", - "T177930-", - "T177931-", - "A177932-", - "C177933-", - "G177934-", - "T177935-", - "A177936-", - "A177937-", - "T177938-", - "C177939-", - "T177940-", - "A177941-", - "T177942-", - "A177943-", - "T177944-", - "A177945-", - "C177946-", - "A177947-", - "A177948-", - "G177949-", - "A177950-", - "T177951-", - "A177952-", - "T177953-", - "A177954-", - "T177955-", - "G177956-", - "A177957-", - "G177958-", - "A177959-", - "G177960-", - "A177961-", - "G177962-", - "A177963-", - "A177964-", - "T177965-", - "G177966-", - "A177967-", - "T177968-", - "A177969-", - "T177970-", - "C177971-", - "A177972-", - "C177973-", - "A177974-", - "G177975-", - "A177976-", - "G177977-", - "T177978-", - "A177979-", - "T177980-", - "C177981-", - "A177982-", - "T177983-", - "A177984-", - "T177985-", - "A177986-", - "G177987-", - "A177988-", - "G177989-", - "A177990-", - "A177991-", - "T177992-", - "A177993-", - "C177994-", - "G177995-", - "A177996-", - "G177997-", - "G177998-", - "T177999-", - "C178000-", - "T178001-", - "G178002-", - "T178003-", - "T178004-", - "T178005-", - "C178006-", - "T178007-", - "A178008-", - "C178009-", - "A178010-", - "C178011-", - "A178012-", - "G178013-", - "A178014-", - "C178015-", - "A178016-", - "T178017-", - "G178018-", - "A178019-", - "A178020-", - "T178021-", - "A178022-", - "A178023-", - "T178024-", - "G178025-", - "A178026-", - "A178027-", - "T178028-", - "A178029-", - "C178030-", - "A178031-", - "C178032-", - "A178033-", - "T178034-", - "A178035-", - "C178036-", - "A178037-", - "A178038-", - "C178039-", - "G178040-", - "T178041-", - "T178042-", - "T178043-", - "T178044-", - "T178045-", - "T178046-", - "T178047-", - "T178048-", - "A178049-", - "A178050-", - "T178051-", - "C178052-", - "T178053-", - "T178054-", - "A178055-", - "G178056-", - "A178057-", - "T178058-", - "A178059-", - "T178060-", - "A178061-", - "A178062-", - "C178063-", - "A178064-", - "C178065-", - "T178066-", - "A178067-", - "A178068-", - "T178069-", - "T178070-", - "A178071-", - "C178072-", - "A178073-", - "T178074-", - "C178075-", - "A178076-", - "A178077-", - "G178078-", - "A178079-", - "T178080-", - "T178081-", - "A178082-", - "T178083-", - "A178084-", - "T178085-", - "A178086-", - "T178087-", - "T178088-", - "G178089-", - "A178090-", - "A178091-", - "A178092-", - "T178093-", - "C178094-", - "G178095-", - "T178096-", - "A178097-", - "A178098-", - "T178099-", - "T178100-", - "T178101-", - "G178102-", - "A178103-", - "G178104-", - "T178105-", - "T178106-", - "G178107-", - "T178108-", - "C178109-", - "T178110-", - "G178111-", - "A178112-", - "T178113-", - "C178114-", - "A178115-", - "T178116-", - "C178117-", - "A178118-", - "T178119-", - "G178120-", - "G178121-", - "A178122-", - "T178123-", - "A178124-", - "T178125-", - "C178126-", - "G178127-", - "A178128-", - "A178129-", - "A178130-", - "A178131-", - "T178132-", - "A178133-", - "A178134-", - "T178135-", - "A178136-", - "T178137-", - "A178138-", - "C178139-", - "G178140-", - "T178141-", - "A178142-", - "A178143-", - "C178144-", - "A178145-", - "T178146-", - "T178147-", - "A178148-", - "G178149-", - "C178150-", - "A178151-", - "A178152-", - "T178153-", - "C178154-", - "T178155-", - "T178156-", - "T178157-", - "T178158-", - "A178159-", - "G178160-", - "A178161-", - "T178162-", - "G178163-", - "A178164-", - "T178165-", - "T178166-", - "G178167-", - "A178168-", - "T178169-", - "A178170-", - "T178171-", - "A178172-", - "T178173-", - "T178174-", - "A178175-", - "T178176-", - "T178177-", - "A178178-", - "T178179-", - "G178180-", - "C178181-", - "G178182-", - "A178183-", - "T178184-", - "G178185-", - "T178186-", - "A178187-", - "A178188-", - "T178189-", - "C178190-", - "A178191-", - "T178192-", - "A178193-", - "A178194-", - "C178195-", - "T178196-", - "A178197-", - "T178198-", - "C178199-", - "G178200-", - "G178201-", - "A178202-", - "G178203-", - "A178204-", - "T178205-", - "G178206-", - "T178207-", - "A178208-", - "G178209-", - "A178210-", - "A178211-", - "A178212-", - "T178213-", - "T178214-", - "A178215-", - "A178216-", - "A178217-", - "G178218-", - "C178219-", - "G178220-", - "C178221-", - "A178222-", - "T178223-", - "A178224-", - "A178225-", - "A178226-", - "A178227-", - "C178228-", - "T178229-", - "A178230-", - "T178231-", - "T178232-", - "T178233-", - "T178234-", - "G178235-", - "G178236-", - "T178237-", - "T178238-", - "G178239-", - "C178240-", - "C178241-", - "G178242-", - "G178243-", - "A178244-", - "T178245-", - "C178246-", - "T178247-", - "A178248-", - "C178249-", - "G178250-", - "T178251-", - "A178252-", - "T178253-", - "T178254-", - "T178255-", - "T178256-", - "A178257-", - "A178258-", - "A178259-", - "A178260-", - "C178261-", - "A178262-", - "A178263-", - "T178264-", - "G178265-", - "T178266-", - "T178267-", - "C178268-", - "A178269-", - "C178270-", - "A178271-", - "A178272-", - "C178273-", - "A178274-", - "T178275-", - "C178276-", - "T178277-", - "A178278-", - "T178279-", - "G178280-", - "A178281-", - "T178282-", - "A178283-", - "G178284-", - "C178285-", - "G178286-", - "A178287-", - "G178288-", - "A178289-", - "G178290-", - "A178291-", - "T178292-", - "C178293-", - "T178294-", - "A178295-", - "G178296-", - "C178297-", - "A178298-", - "A178299-", - "C178300-", - "T178301-", - "A178302-", - "G178303-", - "A178304-", - "G178305-", - "T178306-", - "A178307-", - "A178308-", - "A178309-", - "T178310-", - "A178311-", - "T178312-", - "A178313-", - "C178314-", - "A178315-", - "G178316-", - "A178317-", - "T178318-", - "G178319-", - "T178320-", - "T178321-", - "C178322-", - "G178323-", - "A178324-", - "T178325-", - "A178326-", - "A178327-", - "A178328-", - "G178329-", - "A178330-", - "T178331-", - "G178332-", - "C178333-", - "C178334-", - "G178335-", - "T178336-", - "C178337-", - "A178338-", - "A178339-", - "A178340-", - "A178341-", - "A178342-", - "T178343-", - "A178344-", - "T178345-", - "T178346-", - "G178347-", - "T178348-", - "A178349-", - "C178350-", - "A178351-", - "G178352-", - "T178353-", - "A178354-", - "C178355-", - "T178356-", - "T178357-", - "A178358-", - "T178359-", - "A178360-", - "C178361-", - "A178362-", - "A178363-", - "T178364-", - "A178365-", - "G178366-", - "G178367-", - "T178368-", - "A178369-", - "T178370-", - "A178371-", - "T178372-", - "A178373-", - "A178374-", - "G178375-", - "T178376-", - "T178377-", - "C178378-", - "T178379-", - "A178380-", - "T178381-", - "G178382-", - "A178383-", - "A178384-", - "T178385-", - "G178386-", - "T178387-", - "G178388-", - "A178389-", - "T178390-", - "A178391-", - "G178392-", - "A178393-", - "C178394-", - "A178395-", - "T178396-", - "A178397-", - "T178398-", - "T178399-", - "A178400-", - "A178401-", - "A178402-", - "A178403-", - "T178404-", - "G178405-", - "C178406-", - "A178407-", - "C178408-", - "C178409-", - "G178410-", - "A178411-", - "C178412-", - "T178413-", - "A178414-", - "A178415-", - "G178416-", - "A178417-", - "A178418-", - "C178419-", - "G178420-", - "T178421-", - "A178422-", - "A178423-", - "A178424-", - "A178425-", - "C178426-", - "G178427-", - "A178428-", - "A178429-", - "C178430-", - "T178431-", - "A178432-", - "T178433-", - "A178434-", - "G178435-", - "A178436-", - "A178437-", - "T178438-", - "G178439-", - "T178440-", - "T178441-", - "A178442-", - "T178443-", - "A178444-", - "C178445-", - "A178446-", - "A178447-", - "T178448-", - "G178449-", - "G178450-", - "G178451-", - "T178452-", - "G178453-", - "A178454-", - "T178455-", - "G178456-", - "A178457-", - "T178458-", - "A178459-", - "A178460-", - "G178461-", - "T178462-", - "A178463-", - "G178464-", - "A178465-", - "A178466-", - "G178467-", - "A178468-", - "T178469-", - "G178470-", - "T178471-", - "T178472-", - "A178473-", - "C178474-", - "C178475-", - "C178476-", - "G178477-", - "A178478-", - "T178479-", - "A178480-", - "T178481-", - "A178482-", - "C178483-", - "C178484-", - "C178485-", - "A178486-", - "T178487-", - "A178488-", - "G178489-", - "C178490-", - "A178491-", - "T178492-", - "T178493-", - "A178494-", - "T178495-", - "C178496-", - "T178497-", - "A178498-", - "G178499-", - "T178500-", - "T178501-", - "A178502-", - "T178503-", - "G178504-", - "G178505-", - "C178506-", - "A178507-", - "T178508-", - "G178509-", - "T178510-", - "G178511-", - "T178512-", - "G178513-", - "T178514-", - "A178515-", - "T178516-", - "T178517-", - "A178518-", - "G178519-", - "A178520-", - "T178521-", - "C178522-", - "A178523-", - "A178524-", - "T178525-", - "A178526-", - "C178527-", - "A178528-", - "T178529-", - "A178530-", - "T178531-", - "A178532-", - "C178533-", - "A178534-", - "T178535-", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-", - "A178554-", - "C178555-", - "A178556-", - "C178557-", - "T178558-", - "G178559-", - "A178560-", - "T178561-", - "T178562-", - "A178563-", - "T178564-", - "A178565-", - "C178566-", - "A178567-", - "T178568-", - "C178569-", - "G178570-", - "G178571-", - "T178572-", - "A178573-", - "C178574-", - "A178575-", - "T178576-", - "A178577-", - "C178578-", - "A178579-", - "G178580-", - "T178581-", - "A178582-", - "A178583-", - "A178584-", - "T178585-", - "A178586-", - "G178587-", - "C178588-", - "A178589-", - "T178590-", - "A178591-", - "G178592-", - "A178593-", - "T178594-", - "A178595-", - "T178596-", - "G178597-", - "G178598-", - "A178599-", - "G178600-", - "G178601-", - "A178602-", - "G178603-", - "G178604-", - "A178605-", - "T178606-", - "A178607-", - "C178608-", - "A178609-", - "A178610-", - "A178611-", - "T178612-", - "A178613-", - "T178614-", - "T178615-", - "T178616-", - "C178617-", - "A178618-", - "A178619-", - "A178620-", - "T178621-", - "A178622-", - "A178623-", - "A178624-", - "G178625-", - "T178626-", - "T178627-", - "A178628-", - "T178629-", - "G178630-", - "A178631-", - "G178632-", - "A178633-", - "T178634-", - "A178635-", - "C178636-", - "G178637-", - "C178638-", - "G178639-", - "C178640-", - "T178641-", - "G178642-", - "T178643-", - "C178644-", - "A178645-", - "A178646-", - "T178647-", - "A178648-", - "A178649-", - "T178650-", - "A178651-", - "T178652-", - "A178653-", - "T178654-", - "G178655-", - "G178656-", - "A178657-", - "A178658-", - "G178659-", - "A178660-", - "C178661-", - "A178662-", - "T178663-", - "T178664-", - "A178665-", - "C178666-", - "C178667-", - "T178668-", - "A178669-", - "A178670-", - "C178671-", - "T178672-", - "T178673-", - "C178674-", - "T178675-", - "G178676-", - "A178677-", - "A178678-", - "C178679-", - "T178680-", - "G178681-", - "G178682-", - "A178683-", - "A178684-", - "C178685-", - "T178686-", - "A178687-", - "T178688-", - "A178689-", - "A178690-", - "A178691-", - "T178692-", - "C178693-", - "C178694-", - "A178695-", - "G178696-", - "G178697-", - "C178698-", - "T178699-", - "C178700-", - "T178701-", - "C178702-", - "G178703-", - "C178704-", - "A178705-", - "T178706-", - "A178707-", - "A178708-", - "A178709-", - "G178710-", - "A178711-", - "T178712-", - "G178713-", - "A178714-", - "A178715-", - "T178716-", - "A178717-", - "T178718-", - "A178719-", - "T178720-", - "A178721-", - "T178722-", - "G178723-", - "T178724-", - "T178725-", - "G178726-", - "T178727-", - "A178728-", - "T178729-", - "G178730-", - "C178731-", - "G178732-", - "A178733-", - "C178734-", - "A178735-", - "T178736-", - "C178737-", - "A178738-", - "A178739-", - "A178740-", - "G178741-", - "A178742-", - "T178743-", - "G178744-", - "A178745-", - "A178746-", - "A178747-", - "A178748-", - "A178749-", - "A178750-", - "T178751-", - "G178752-", - "T178753-", - "T178754-", - "A178755-", - "A178756-", - "G178757-", - "A178758-", - "C178759-", - "T178760-", - "T178761-", - "A178762-", - "T178763-", - "A178764-", - "T178765-", - "A178766-", - "T178767-", - "T178768-", - "T178769-", - "A178770-", - "G178771-", - "A178772-", - "T178773-", - "A178774-", - "T178775-", - "A178776-", - "A178777-", - "C178778-", - "A178779-", - "C178780-", - "G178781-", - "A178782-", - "A178783-", - "T178784-", - "A178785-", - "T178786-", - "G178787-", - "T178788-", - "A178789-", - "T178790-", - "G178791-", - "A178792-", - "C178793-", - "G178794-", - "G178795-", - "A178796-", - "T178797-", - "G178798-", - "G178799-", - "G178800-", - "A178801-", - "A178802-", - "T178803-", - "T178804-", - "G178805-", - "G178806-", - "T178807-", - "A178808-", - "A178809-", - "C178810-", - "G178811-", - "A178812-", - "T178813-", - "G178814-", - "A178815-", - "C178816-", - "A178817-", - "G178818-", - "A178819-", - "A178820-", - "A178821-", - "G178822-", - "C178823-", - "A178824-", - "G178825-", - "A178826-", - "T178827-", - "T178828-", - "G178829-", - "T178830-", - "C178831-", - "A178832-", - "G178833-", - "C178834-", - "T178835-", - "C178836-", - "T178837-", - "G178838-", - "C178839-", - "A178840-", - "T178841-", - "A178842-", - "C178843-", - "T178844-", - "A178845-", - "T178846-", - "T178847-", - "C178848-", - "T178849-", - "T178850-", - "C178851-", - "A178852-", - "T178853-", - "G178854-", - "A178855-", - "C178856-", - "A178857-", - "A178858-", - "T178859-", - "A178860-", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-", - "G178879-", - "T178880-", - "T178881-", - "A178882-", - "T178883-", - "G178884-", - "A178885-", - "A178886-", - "G178887-", - "C178888-", - "G178889-", - "T178890-", - "A178891-", - "T178892-", - "A178893-", - "T178894-", - "G178895-", - "T178896-", - "T178897-", - "A178898-", - "C178899-", - "A178900-", - "A178901-", - "G178902-", - "A178903-", - "T178904-", - "A178905-", - "C178906-", - "A178907-", - "T178908-", - "T178909-", - "T178910-", - "A178911-", - "A178912-", - "T178913-", - "G178914-", - "T178915-", - "G178916-", - "C178917-", - "T178918-", - "T178919-", - "A178920-", - "C178921-", - "G178922-", - "G178923-", - "A178924-", - "A178925-", - "C178926-", - "A178927-", - "T178928-", - "A178929-", - "T178930-", - "A178931-", - "T178932-", - "T178933-", - "T178934-", - "A178935-", - "G178936-", - "A178937-", - "A178938-", - "A178939-", - "C178940-", - "A178941-", - "T178942-", - "C178943-", - "T178944-", - "A178945-", - "C178946-", - "T178947-", - "A178948-", - "A178949-", - "C178950-", - "G178951-", - "A178952-", - "T178953-", - "T178954-", - "T178955-", - "T178956-", - "T178957-", - "T178958-", - "A178959-", - "T178960-", - "G178961-", - "C178962-", - "T178963-", - "T178964-", - "G178965-", - "T178966-", - "A178967-", - "T178968-", - "T178969-", - "A178970-", - "T178971-", - "T178972-", - "A178973-", - "A178974-", - "T178975-", - "G178976-", - "G178977-", - "T178978-", - "A178979-", - "T178980-", - "G178981-", - "T178982-", - "A178983-", - "A178984-", - "T178985-", - "A178986-", - "T178987-", - "G178988-", - "A178989-", - "T178990-", - "T178991-", - "T178992-", - "A178993-", - "A178994-", - "T178995-", - "T178996-", - "G178997-", - "A178998-", - "T178999-", - "T179000-", - "G179001-", - "T179002-", - "G179003-", - "T179004-", - "A179005-", - "C179006-", - "A179007-", - "C179008-", - "G179009-", - "A179010-", - "T179011-", - "A179012-", - "C179013-", - "C179014-", - "A179015-", - "A179016-", - "T179017-", - "T179018-", - "T179019-", - "G179020-", - "T179021-", - "C179022-", - "G179023-", - "A179024-", - "G179025-", - "T179026-", - "A179027-", - "T179028-", - "G179029-", - "A179030-", - "A179031-", - "T179032-", - "A179033-", - "C179034-", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "G181049-", - "T181102-", - "A181103-", - "T181104-", - "A181105-", - "T181106-", - "T181107-", - "C181108-", - "C181109-", - "T181110-", - "A181246-", - "T183553-", - "A183554-", - "C183555-", - "T187073-", - "T187207-", - "T187770-", - "T189739-", - "A190198-", - "C190199-", - "A190396-", - "A192435-", - "A192436-", - "G192437-", - "T192438-", - "C192439-", - "A192440-", - "T192441-", - "A192442-", - "A192443-", - "G192444-", - "T192445-", - "T192446-", - "A192447-", - "G192448-", - "T192449-", - "T192450-", - "A192451-", - "A192452-", - "G192453-", - "T192454-", - "C192455-", - "A192456-", - "T192457-", - "A192458-", - "A192459-", - "G192460-", - "T192461-", - "T192462-", - "A192463-", - "G192464-", - "T192465-", - "T192466-", - "A192467-", - "A192468-", - "G192469-", - "T192470-", - "C192471-", - "A192472-", - "T192473-", - "A192474-", - "A192475-", - "G192476-", - "T192477-", - "T192478-", - "A192479-", - "G192480-", - "T192481-", - "T192482-", - "A192483-", - "A192484-", - "G192485-", - "T192486-", - "C192487-", - "A192488-", - "T192489-", - "A192490-", - "A192491-", - "G192492-", - "T192493-", - "T192494-", - "A192495-", - "G192496-", - "T192497-", - "T192498-", - "A192499-", - "A192500-", - "G192501-", - "T192502-", - "C192503-", - "A192504-", - "T192505-", - "A192506-", - "A192507-", - "G192508-", - "T192509-", - "T192510-", - "A192511-", - "G192512-", - "T192513-", - "T192514-", - "A192515-", - "A192516-", - "G192517-", - "T193611C" - ], - "OPG003": [ - "Y337H" - ], - "OPG021": [ - "K230X", - "*243X" - ], - "OPG022": [ - "K121X", - "*127X" - ], - "OPG029": [ - "D153-", - "D154-" - ], - "OPG031": [ - "G258-" - ], - "OPG044": [ - "E145X", - "*150X" - ], - "OPG049": [ - "R314X", - "H315X", - "*319X" - ], - "OPG050": [ - "F72X", - "*76X" - ], - "OPG054": [ - "K144X", - "*440X" - ], - "OPG061": [ - "K49X", - "*232X" - ], - "OPG063": [ - "F65X", - "*480X" - ], - "OPG064": [ - "L261X", - "*738X" - ], - "OPG075": [ - "F75X", - "*109X" - ], - "OPG078": [ - "F56X", - "*74X" - ], - "OPG082": [ - "I362X", - "*383X" - ], - "OPG084": [ - "F10X", - "*677X" - ], - "OPG085": [ - "S565X", - "K585X", - "*592X" - ], - "OPG092": [ - "N351X", - "*372X" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG104": [ - "N60X", - "*134X" - ], - "OPG105": [ - "R281X", - "*1287X" - ], - "OPG109": [ - "F116X", - "K206X", - "K683X", - "*796X" - ], - "OPG114": [ - "K9X", - "I10X", - "*147X" - ], - "OPG117": [ - "F501X", - "*786X" - ], - "OPG122": [ - "F106X", - "*249X" - ], - "OPG123": [ - "N570X", - "*632X" - ], - "OPG124": [ - "N205X", - "*288X" - ], - "OPG125": [ - "G499X", - "*552X" - ], - "OPG133": [ - "G144X", - "*711X" - ], - "OPG136": [ - "N877X", - "*892X" - ], - "OPG138": [ - "N6X", - "*191X" - ], - "OPG145": [ - "L14X", - "L258X", - "*493X" - ], - "OPG149": [ - "I184X", - "K185X", - "*188X" - ], - "OPG150": [ - "*383X" - ], - "OPG151": [ - "K2X", - "K946X", - "*1165X" - ], - "OPG154": [ - "K57X", - "*111X" - ], - "OPG155": [ - "F8X", - "*147X" - ], - "OPG157": [ - "Q61X", - "H62X", - "*79X" - ], - "OPG159": [ - "N113X", - "N114-", - "N115-", - "Y116X", - "*146X" - ], - "OPG164": [ - "L227X", - "*229X" - ], - "OPG170": [ - "I218X", - "*222X" - ], - "OPG173": [ - "K34X", - "E57X", - "*75X" - ], - "OPG180": [ - "K243X", - "S554X", - "*560X" - ], - "OPG188": [ - "K436X", - "*504X" - ], - "OPG191": [ - "Y165X", - "F166X", - "*169X" - ], - "OPG193": [ - "F263X", - "*268X" - ], - "OPG197": [ - "D17-", - "S18-", - "V36X", - "E37-", - "D38-", - "I39-", - "M40-", - "N41-", - "E42-", - "I43X", - "*101X" - ], - "OPG198": [ - "Q229X", - "*283X" - ], - "OPG204": [ - "M1-", - "K2-", - "M3-", - "K4-", - "M5-", - "M6-", - "V7-", - "R8-", - "I9-", - "Y10-", - "F11-", - "V12-", - "S13-", - "L14-", - "S15-", - "L16-", - "L17-", - "L18-", - "F19-", - "H20-", - "S21-", - "Y22-", - "A23-", - "I24-", - "D25-", - "I26-", - "E27-", - "N28-", - "E29-", - "I30-", - "T31-", - "E32-", - "F33-", - "F34-", - "N35-", - "K36-", - "M37-", - "R38-", - "D39-", - "T40-", - "L41-", - "P42-", - "A43-", - "K44-", - "D45-", - "S46-", - "K47-", - "W48-", - "L49-", - "N50-", - "P51-", - "V52-", - "C53-", - "M54-", - "F55-", - "G56-", - "G57-", - "T58-", - "M59-", - "N60-", - "D61-", - "M62-", - "A63-", - "A64-", - "L65-", - "G66-", - "E67-", - "P68-", - "F69-", - "S70-", - "A71-", - "K72-", - "C73-", - "P74-", - "P75-", - "I76-", - "E77-", - "D78-", - "S79-", - "L80-", - "L81-", - "S82-", - "H83-", - "R84-", - "Y85-", - "K86-", - "D87-", - "Y88-", - "V89-", - "V90-", - "K91-", - "W92-", - "E93-", - "R94-", - "L95-", - "E96-", - "K97-", - "N98-", - "R99-", - "R100-", - "R101-", - "Q102-", - "V103-", - "S104-", - "N105-", - "K106-", - "R107-", - "V108-", - "K109-", - "H110-", - "G111-", - "D112-", - "L113-", - "W114-", - "I115-", - "A116-", - "N117-", - "Y118-", - "T119-", - "S120-", - "K121-", - "F122-", - "S123-", - "N124-", - "R125-", - "R126-", - "Y127-", - "L128-", - "C129-", - "T130-", - "V131-", - "T132-", - "T133-", - "K134-", - "N135-", - "G136-", - "D137-", - "C138-", - "V139-", - "Q140-", - "G141-", - "V142-", - "V143-", - "R144-", - "S145-", - "H146-", - "V147-", - "W148-", - "K149-", - "P150-", - "S151-", - "S152-", - "C153-", - "I154-", - "P155-", - "K156-", - "T157-", - "Y158-", - "E159-", - "L160-", - "G161-", - "T162-", - "Y163-", - "D164-", - "K165-", - "Y166-", - "G167-", - "I168-", - "D169-", - "L170-", - "Y171-", - "C172-", - "G173-", - "I174-", - "L175-", - "Y176-", - "A177-", - "N178-", - "H179-", - "Y180-", - "N181-", - "N182-", - "I183-", - "T184-", - "W185-", - "Y186-", - "K187-", - "D188-", - "N189-", - "K190-", - "E191-", - "I192-", - "N193-", - "I194-", - "D195-", - "D196-", - "F197-", - "K198-", - "Y199-", - "S200-", - "Q201-", - "A202-", - "G203-", - "K204-", - "E205-", - "L206-", - "I207-", - "I208-", - "H209-", - "N210-", - "P211-", - "E212-", - "L213-", - "E214-", - "D215-", - "S216-", - "G217-", - "R218-", - "Y219-", - "D220-", - "C221-", - "Y222-", - "V223-", - "H224-", - "Y225-", - "D226-", - "D227-", - "V228-", - "R229-", - "I230-", - "K231-", - "N232-", - "D233-", - "I234-", - "V235-", - "V236-", - "S237-", - "R238-", - "C239-", - "K240-", - "I241-", - "L242-", - "T243-", - "V244-", - "I245-", - "P246-", - "S247-", - "Q248-", - "D249-", - "H250-", - "R251-", - "F252-", - "K253-", - "L254-", - "I255-", - "L256-", - "D257-", - "P258-", - "K259-", - "I260-", - "N261-", - "V262-", - "T263-", - "I264-", - "G265-", - "E266-", - "P267-", - "A268-", - "N269-", - "I270-", - "T271-", - "C272-", - "S273-", - "A274-", - "V275-", - "S276-", - "T277-", - "S278-", - "L279-", - "F280-", - "V281-", - "D282-", - "D283-", - "V284-", - "L285-", - "I286-", - "E287-", - "W288-", - "E289-", - "N290-", - "P291-", - "S292-", - "G293-", - "W294-", - "I295-", - "I296-", - "G297-", - "L298-", - "D299-", - "F300-", - "G301-", - "V302-", - "Y303-", - "S304-", - "I305-", - "L306-", - "T307-", - "S308-", - "R309-", - "G310-", - "G311-", - "I312-", - "T313-", - "E314-", - "A315-", - "T316-", - "L317-", - "Y318-", - "F319-", - "E320-", - "N321-", - "V322-", - "T323-", - "E324-", - "E325-", - "Y326-", - "I327-", - "G328-", - "N329-", - "T330-", - "Y331-", - "T332-", - "C333-", - "R334-", - "G335-", - "H336-", - "N337-", - "Y338-", - "Y339-", - "F340-", - "D341-", - "K342-", - "T343-", - "L344-", - "T345-", - "T346-", - "T347-", - "V348-", - "V349-", - "L350-", - "E351-", - "*352-" - ], - "OPG205": [ - "M1-", - "D2-", - "E3-", - "D4-", - "T5-", - "R6-", - "L7-", - "S8-", - "R9-", - "Y10-", - "L11-", - "Y12-", - "L13-", - "T14-", - "D15-", - "R16-", - "E17-", - "H18-", - "I19-", - "N20-", - "V21-", - "D22-", - "S23-", - "I24-", - "K25-", - "Q26-", - "L27-", - "C28-", - "K29-", - "I30-", - "S31-", - "D32-", - "P33-", - "N34-", - "A35-", - "C36-", - "Y37-", - "R38-", - "C39-", - "G40-", - "C41-", - "T42-", - "A43-", - "L44-", - "H45-", - "E46-", - "Y47-", - "F48-", - "Y49-", - "N50-", - "Y51-", - "R52-", - "S53-", - "V54-", - "N55-", - "G56-", - "K57-", - "Y58-", - "K59-", - "Y60-", - "R61-", - "Y62-", - "N63-", - "G64-", - "Y65-", - "Y66-", - "Q67-", - "Y68-", - "Y69-", - "S70-", - "S71-", - "S72-", - "D73-", - "Y74-", - "E75-", - "N76-", - "Y77-", - "N78-", - "E79-", - "Y80-", - "Y81-", - "Y82-", - "D83-", - "D84-", - "Y85-", - "D86-", - "R87-", - "T88-", - "G89-", - "M90-", - "N91-", - "S92-", - "E93-", - "S94-", - "D95-", - "N96-", - "I97-", - "S98-", - "I99-", - "K100-", - "T101-", - "E102-", - "Y103-", - "E104-", - "N105-", - "E106-", - "Y107-", - "E108-", - "F109-", - "Y110-", - "D111-", - "E112-", - "T113-", - "Q114-", - "D115-", - "Q116-", - "S117-", - "T118-", - "Q119-", - "L120-", - "V121-", - "D122-", - "Y123-", - "D124-", - "I125-", - "K126-", - "L127-", - "K128-", - "T129-", - "N130-", - "E131-", - "D132-", - "D133-", - "F134-", - "V135-", - "D136-", - "E137-", - "F138-", - "Y139-", - "G140-", - "Y141-", - "D142-", - "R143-", - "S144-", - "V145-", - "G146-", - "V147-", - "H148-", - "D149-", - "Y150-", - "I151-", - "D152-", - "V153-", - "S154-", - "I155-", - "N156-", - "K157-", - "V158-", - "V159-", - "Y160-", - "G161-", - "R162-", - "E163-", - "S164-", - "H165-", - "V166-", - "R167-", - "W168-", - "W169-", - "D170-", - "I171-", - "W172-", - "Q173-", - "E174-", - "H175-", - "N176-", - "D177-", - "G178-", - "V179-", - "Y180-", - "S181-", - "I182-", - "G183-", - "K184-", - "E185-", - "C186-", - "I187-", - "D188-", - "N189-", - "I190-", - "Y191-", - "E192-", - "D193-", - "R194-", - "H195-", - "T196-", - "V197-", - "D198-", - "E199-", - "F200-", - "Y201-", - "K202-", - "I203-", - "D204-", - "S205-", - "V206-", - "S207-", - "D208-", - "V209-", - "D210-", - "D211-", - "A212-", - "E213-", - "H214-", - "I215-", - "S216-", - "Q217-", - "I218-", - "T219-", - "N220-", - "D221-", - "V222-", - "S223-", - "T224-", - "Q225-", - "T226-", - "W227-", - "E228-", - "K229-", - "K230-", - "S231-", - "E232-", - "L233-", - "D234-", - "R235-", - "Y236-", - "M237-", - "E238-", - "M239-", - "Y240-", - "P241-", - "R242-", - "H243-", - "R244-", - "Y245-", - "G246-", - "K247-", - "H248-", - "S249-", - "V250-", - "F251-", - "K252-", - "G253-", - "F254-", - "S255-", - "D256-", - "K257-", - "V258-", - "R259-", - "K260-", - "N261-", - "D262-", - "L263-", - "D264-", - "M265-", - "N266-", - "V267-", - "V268-", - "K269-", - "E270-", - "L271-", - "L272-", - "S273-", - "N274-", - "G275-", - "A276-", - "S277-", - "L278-", - "T279-", - "I280-", - "K281-", - "D282-", - "S283-", - "S284-", - "N285-", - "K286-", - "D287-", - "P288-", - "I289-", - "A290-", - "V291-", - "Y292-", - "F293-", - "R294-", - "R295-", - "T296-", - "I297-", - "M298-", - "N299-", - "L300-", - "E301-", - "M302-", - "I303-", - "D304-", - "I305-", - "I306-", - "N307-", - "K308-", - "H309-", - "T310-", - "T311-", - "I312-", - "Y313-", - "E314-", - "R315-", - "R316-", - "Y317-", - "I318-", - "V319-", - "H320-", - "S321-", - "Y322-", - "L323-", - "K324-", - "N325-", - "Y326-", - "R327-", - "N328-", - "F329-", - "D330-", - "Y331-", - "P332-", - "F333-", - "F334-", - "R335-", - "K336-", - "L337-", - "V338-", - "L339-", - "T340-", - "N341-", - "K342-", - "H343-", - "C344-", - "L345-", - "N346-", - "N347-", - "Y348-", - "C349-", - "N350-", - "I351-", - "S352-", - "D353-", - "G354-", - "K355-", - "Y356-", - "G357-", - "T358-", - "P359-", - "L360-", - "H361-", - "I362-", - "L363-", - "A364-", - "S365-", - "N366-", - "K367-", - "K368-", - "I369-", - "I370-", - "T371-", - "P372-", - "N373-", - "Y374-", - "M375-", - "K376-", - "L377-", - "L378-", - "V379-", - "Y380-", - "N381-", - "G382-", - "N383-", - "D384-", - "I385-", - "N386-", - "A387-", - "R388-", - "G389-", - "E390-", - "D391-", - "T392-", - "Q393-", - "M394-", - "R395-", - "T396-", - "P397-", - "L398-", - "H399-", - "K400-", - "Y401-", - "L402-", - "C403-", - "K404-", - "F405-", - "V406-", - "Y407-", - "H408-", - "N409-", - "I410-", - "E411-", - "Y412-", - "G413-", - "I414-", - "R415-", - "Y416-", - "Y417-", - "N418-", - "E419-", - "K420-", - "I421-", - "I422-", - "D423-", - "A424-", - "F425-", - "I426-", - "E427-", - "L428-", - "G429-", - "A430-", - "D431-", - "L432-", - "T433-", - "I434-", - "P435-", - "N436-", - "D437-", - "D438-", - "G439-", - "M440-", - "I441-", - "P442-", - "V443-", - "V444-", - "Y445-", - "C446-", - "I447-", - "H448-", - "S449-", - "N450-", - "A451-", - "E452-", - "Y453-", - "G454-", - "Y455-", - "N456-", - "N457-", - "I458-", - "T459-", - "N460-", - "I461-", - "K462-", - "I463-", - "I464-", - "R465-", - "K466-", - "L467-", - "L468-", - "N469-", - "L470-", - "S471-", - "R472-", - "H473-", - "A474-", - "S475-", - "H476-", - "N477-", - "L478-", - "F479-", - "R480-", - "D481-", - "R482-", - "V483-", - "M484-", - "H485-", - "D486-", - "Y487-", - "I488-", - "S489-", - "N490-", - "T491-", - "Y492-", - "I493-", - "D494-", - "L495-", - "E496-", - "C497-", - "L498-", - "D499-", - "I500-", - "I501-", - "R502-", - "S503-", - "L504-", - "D505-", - "G506-", - "Y507-", - "D508-", - "I509-", - "N510-", - "C511-", - "Y512-", - "F513-", - "E514-", - "G515-", - "R516-", - "T517-", - "P518-", - "L519-", - "H520-", - "C521-", - "A522-", - "I523-", - "Q524-", - "Y525-", - "N526-", - "F527-", - "T528-", - "Q529-", - "I530-", - "A531-", - "E532-", - "Y533-", - "L534-", - "L535-", - "D536-", - "R537-", - "G538-", - "A539-", - "D540-", - "I541-", - "S542-", - "L543-", - "K544-", - "T545-", - "D546-", - "D547-", - "G548-", - "K549-", - "T550-", - "V551-", - "F552-", - "D553-", - "L554-", - "S555-", - "L556-", - "C557-", - "S558-", - "Y559-", - "I560-", - "P561-", - "L562-", - "K563-", - "W564-", - "T565-", - "S566-", - "F567-", - "L568-", - "I569-", - "S570-", - "R571-", - "L572-", - "P573-", - "P574-", - "K575-", - "S576-", - "V577-", - "I578-", - "C579-", - "S580-", - "L581-", - "T582-", - "N583-", - "H584-", - "I585-", - "I586-", - "D587-", - "Y588-", - "V589-", - "L590-", - "T591-", - "N592-", - "N593-", - "R594-", - "R595-", - "I596-", - "I597-", - "W598-", - "Q599-", - "S600-", - "Q601-", - "M602-", - "I603-", - "N604-", - "K605-", - "Y606-", - "V607-", - "L608-", - "L609-", - "L610-", - "D611-", - "P612-", - "S613-", - "F614-", - "Y615-", - "Y616-", - "R617-", - "F618-", - "R619-", - "N620-", - "V621-", - "I622-", - "E623-", - "N624-", - "K625-", - "L626-", - "D627-", - "Q628-", - "Y629-", - "N630-", - "N631-", - "R632-", - "Y633-", - "N634-", - "M635-", - "F636-", - "E637-", - "H638-", - "D639-", - "R640-", - "D641-", - "V642-", - "N643-", - "E644-", - "K645-", - "Y646-", - "G647-", - "K648-", - "V649-", - "L650-", - "H651-", - "D652-", - "L653-", - "D654-", - "T655-", - "Y656-", - "I657-", - "K658-", - "D659-", - "V660-", - "Q661-", - "V662-", - "L663-", - "K664-", - "S665-", - "T666-", - "S667-", - "I668-", - "T669-", - "N670-", - "N671-", - "I672-", - "T673-", - "L674-", - "Y675-", - "D676-", - "T677-", - "I678-", - "I679-", - "N680-", - "N681-", - "K682-", - "S683-", - "E684-", - "F685-", - "P686-", - "I687-", - "R688-", - "R689-", - "V690-", - "N691-", - "D692-", - "K693-", - "Q694-", - "L695-", - "I696-", - "N697-", - "L698-", - "I699-", - "K700-", - "S701-", - "N702-", - "T703-", - "Y704-", - "H705-", - "N706-", - "L707-", - "I708-", - "E709-", - "K710-", - "V711-", - "I712-", - "K713-", - "N714-", - "T715-", - "L716-", - "E717-", - "K718-", - "Y719-", - "T720-", - "L721-", - "T722-", - "N723-", - "I724-", - "V725-", - "L726-", - "E727-", - "Y728-", - "M729-", - "I730-", - "S731-", - "S732-", - "R733-", - "S734-", - "Q735-", - "S736-", - "S737-", - "Y738-", - "L739-", - "S740-", - "R741-", - "I742-", - "P743-", - "N744-", - "E745-", - "I746-", - "L747-", - "L748-", - "E749-", - "I750-", - "L751-", - "Y752-", - "K753-", - "L754-", - "D755-", - "M756-", - "Y757-", - "D758-", - "L759-", - "R760-", - "N761-", - "L762-", - "Y763-", - "T764-", - "R765-", - "Y766-", - "M767-", - "R768-", - "E769-", - "N770-", - "D771-", - "I772-", - "T773-", - "E774-", - "Y775-", - "H776-", - "I777-", - "E778-", - "N779-", - "T780-", - "R781-", - "S782-", - "V783-", - "S784-", - "T785-", - "Q786-", - "T787-", - "*788-" - ], - "OPG209": [ - "G178X", - "*191X" - ], - "OPG210": [ - "L733X", - "L734X", - "*1881X" - ] - }, - "labels": { - "aa": "OPG003: Y337H; OPG021: K230X, *243X; OPG022: K121X, *127X; OPG029: D153-, D154-; OPG031: G258-; OPG044: E145X, *150X; OPG049: R314X, H315X, *319X; OPG050: F72X, *76X; OPG054: K144X, *440X; OPG061: K49X, *232X; OPG063: F65X, *480X; OPG064: L261X, *738X; OPG075: F75X, *109X; OPG078: F56X, *74X; OPG082: I362X, *383X; OPG084: F10X, *677X; OPG085: S565X, K585X, *592X; OPG092: N351X, *372X; OPG097: K266X, *345X; OPG104: N60X, *134X; OPG105: R281X, *1287X; OPG109: F116X, K206X, K683X, *796X; OPG114: K9X, I10X, *147X; OPG117: F501X, *786X; OPG122: F106X, *249X; OPG123: N570X, *632X; OPG124: N205X, *288X; OPG125: G499X, *552X; OPG133: G144X, *711X; OPG136: N877X, *892X; OPG138: N6X, *191X; OPG145: L14X, L258X, *493X; OPG149: I184X, K185X, *188X; OPG150: *383X; OPG151: K2X, K946X, *1165X; OPG154: K57X, *111X; OPG155: F8X, *147X; OPG157: Q61X, H62X, *79X; OPG159: N113X, N114-, N115-, Y116X, *146X; OPG164: L227X, *229X; OPG170: I218X, *222X; OPG173: K34X, E57X, *75X; OPG180: K243X, S554X, *560X; OPG188: K436X, *504X; OPG191: Y165X, F166X, *169X; OPG193: F263X, *268X; OPG197: D17-, S18-, V36X, E37-, D38-, I39-, M40-, N41-, E42-, I43X, *101X; OPG198: Q229X, *283X; OPG204: M1-, K2-, M3-, K4-, M5-, M6-, V7-, R8-, I9-, Y10-, F11-, V12-, S13-, L14-, S15-, L16-, L17-, L18-, F19-, H20-, S21-, Y22-, A23-, I24-, D25-, I26-, E27-, N28-, E29-, I30-, T31-, E32-, F33-, F34-, N35-, K36-, M37-, R38-, D39-, T40-, L41-, P42-, A43-, K44-, D45-, S46-, K47-, W48-, L49-, N50-, P51-, V52-, C53-, M54-, F55-, G56-, G57-, T58-, M59-, N60-, D61-, M62-, A63-, A64-, L65-, G66-, E67-, P68-, F69-, S70-, A71-, K72-, C73-, P74-, P75-, I76-, E77-, D78-, S79-, L80-, L81-, S82-, H83-, R84-, Y85-, K86-, D87-, Y88-, V89-, V90-, K91-, W92-, E93-, R94-, L95-, E96-, K97-, N98-, R99-, R100-, R101-, Q102-, V103-, S104-, N105-, K106-, R107-, V108-, K109-, H110-, G111-, D112-, L113-, W114-, I115-, A116-, N117-, Y118-, T119-, S120-, K121-, F122-, S123-, N124-, R125-, R126-, Y127-, L128-, C129-, T130-, V131-, T132-, T133-, K134-, N135-, G136-, D137-, C138-, V139-, Q140-, G141-, V142-, V143-, R144-, S145-, H146-, V147-, W148-, K149-, P150-, S151-, S152-, C153-, I154-, P155-, K156-, T157-, Y158-, E159-, L160-, G161-, T162-, Y163-, D164-, K165-, Y166-, G167-, I168-, D169-, L170-, Y171-, C172-, G173-, I174-, L175-, Y176-, A177-, N178-, H179-, Y180-, N181-, N182-, I183-, T184-, W185-, Y186-, K187-, D188-, N189-, K190-, E191-, I192-, N193-, I194-, D195-, D196-, F197-, K198-, Y199-, S200-, Q201-, A202-, G203-, K204-, E205-, L206-, I207-, I208-, H209-, N210-, P211-, E212-, L213-, E214-, D215-, S216-, G217-, R218-, Y219-, D220-, C221-, Y222-, V223-, H224-, Y225-, D226-, D227-, V228-, R229-, I230-, K231-, N232-, D233-, I234-, V235-, V236-, S237-, R238-, C239-, K240-, I241-, L242-, T243-, V244-, I245-, P246-, S247-, Q248-, D249-, H250-, R251-, F252-, K253-, L254-, I255-, L256-, D257-, P258-, K259-, I260-, N261-, V262-, T263-, I264-, G265-, E266-, P267-, A268-, N269-, I270-, T271-, C272-, S273-, A274-, V275-, S276-, T277-, S278-, L279-, F280-, V281-, D282-, D283-, V284-, L285-, I286-, E287-, W288-, E289-, N290-, P291-, S292-, G293-, W294-, I295-, I296-, G297-, L298-, D299-, F300-, G301-, V302-, Y303-, S304-, I305-, L306-, T307-, S308-, R309-, G310-, G311-, I312-, T313-, E314-, A315-, T316-, L317-, Y318-, F319-, E320-, N321-, V322-, T323-, E324-, E325-, Y326-, I327-, G328-, N329-, T330-, Y331-, T332-, C333-, R334-, G335-, H336-, N337-, Y338-, Y339-, F340-, D341-, K342-, T343-, L344-, T345-, T346-, T347-, V348-, V349-, L350-, E351-, *352-; OPG205: M1-, D2-, E3-, D4-, T5-, R6-, L7-, S8-, R9-, Y10-, L11-, Y12-, L13-, T14-, D15-, R16-, E17-, H18-, I19-, N20-, V21-, D22-, S23-, I24-, K25-, Q26-, L27-, C28-, K29-, I30-, S31-, D32-, P33-, N34-, A35-, C36-, Y37-, R38-, C39-, G40-, C41-, T42-, A43-, L44-, H45-, E46-, Y47-, F48-, Y49-, N50-, Y51-, R52-, S53-, V54-, N55-, G56-, K57-, Y58-, K59-, Y60-, R61-, Y62-, N63-, G64-, Y65-, Y66-, Q67-, Y68-, Y69-, S70-, S71-, S72-, D73-, Y74-, E75-, N76-, Y77-, N78-, E79-, Y80-, Y81-, Y82-, D83-, D84-, Y85-, D86-, R87-, T88-, G89-, M90-, N91-, S92-, E93-, S94-, D95-, N96-, I97-, S98-, I99-, K100-, T101-, E102-, Y103-, E104-, N105-, E106-, Y107-, E108-, F109-, Y110-, D111-, E112-, T113-, Q114-, D115-, Q116-, S117-, T118-, Q119-, L120-, V121-, D122-, Y123-, D124-, I125-, K126-, L127-, K128-, T129-, N130-, E131-, D132-, D133-, F134-, V135-, D136-, E137-, F138-, Y139-, G140-, Y141-, D142-, R143-, S144-, V145-, G146-, V147-, H148-, D149-, Y150-, I151-, D152-, V153-, S154-, I155-, N156-, K157-, V158-, V159-, Y160-, G161-, R162-, E163-, S164-, H165-, V166-, R167-, W168-, W169-, D170-, I171-, W172-, Q173-, E174-, H175-, N176-, D177-, G178-, V179-, Y180-, S181-, I182-, G183-, K184-, E185-, C186-, I187-, D188-, N189-, I190-, Y191-, E192-, D193-, R194-, H195-, T196-, V197-, D198-, E199-, F200-, Y201-, K202-, I203-, D204-, S205-, V206-, S207-, D208-, V209-, D210-, D211-, A212-, E213-, H214-, I215-, S216-, Q217-, I218-, T219-, N220-, D221-, V222-, S223-, T224-, Q225-, T226-, W227-, E228-, K229-, K230-, S231-, E232-, L233-, D234-, R235-, Y236-, M237-, E238-, M239-, Y240-, P241-, R242-, H243-, R244-, Y245-, G246-, K247-, H248-, S249-, V250-, F251-, K252-, G253-, F254-, S255-, D256-, K257-, V258-, R259-, K260-, N261-, D262-, L263-, D264-, M265-, N266-, V267-, V268-, K269-, E270-, L271-, L272-, S273-, N274-, G275-, A276-, S277-, L278-, T279-, I280-, K281-, D282-, S283-, S284-, N285-, K286-, D287-, P288-, I289-, A290-, V291-, Y292-, F293-, R294-, R295-, T296-, I297-, M298-, N299-, L300-, E301-, M302-, I303-, D304-, I305-, I306-, N307-, K308-, H309-, T310-, T311-, I312-, Y313-, E314-, R315-, R316-, Y317-, I318-, V319-, H320-, S321-, Y322-, L323-, K324-, N325-, Y326-, R327-, N328-, F329-, D330-, Y331-, P332-, F333-, F334-, R335-, K336-, L337-, V338-, L339-, T340-, N341-, K342-, H343-, C344-, L345-, N346-, N347-, Y348-, C349-, N350-, I351-, S352-, D353-, G354-, K355-, Y356-, G357-, T358-, P359-, L360-, H361-, I362-, L363-, A364-, S365-, N366-, K367-, K368-, I369-, I370-, T371-, P372-, N373-, Y374-, M375-, K376-, L377-, L378-, V379-, Y380-, N381-, G382-, N383-, D384-, I385-, N386-, A387-, R388-, G389-, E390-, D391-, T392-, Q393-, M394-, R395-, T396-, P397-, L398-, H399-, K400-, Y401-, L402-, C403-, K404-, F405-, V406-, Y407-, H408-, N409-, I410-, E411-, Y412-, G413-, I414-, R415-, Y416-, Y417-, N418-, E419-, K420-, I421-, I422-, D423-, A424-, F425-, I426-, E427-, L428-, G429-, A430-, D431-, L432-, T433-, I434-, P435-, N436-, D437-, D438-, G439-, M440-, I441-, P442-, V443-, V444-, Y445-, C446-, I447-, H448-, S449-, N450-, A451-, E452-, Y453-, G454-, Y455-, N456-, N457-, I458-, T459-, N460-, I461-, K462-, I463-, I464-, R465-, K466-, L467-, L468-, N469-, L470-, S471-, R472-, H473-, A474-, S475-, H476-, N477-, L478-, F479-, R480-, D481-, R482-, V483-, M484-, H485-, D486-, Y487-, I488-, S489-, N490-, T491-, Y492-, I493-, D494-, L495-, E496-, C497-, L498-, D499-, I500-, I501-, R502-, S503-, L504-, D505-, G506-, Y507-, D508-, I509-, N510-, C511-, Y512-, F513-, E514-, G515-, R516-, T517-, P518-, L519-, H520-, C521-, A522-, I523-, Q524-, Y525-, N526-, F527-, T528-, Q529-, I530-, A531-, E532-, Y533-, L534-, L535-, D536-, R537-, G538-, A539-, D540-, I541-, S542-, L543-, K544-, T545-, D546-, D547-, G548-, K549-, T550-, V551-, F552-, D553-, L554-, S555-, L556-, C557-, S558-, Y559-, I560-, P561-, L562-, K563-, W564-, T565-, S566-, F567-, L568-, I569-, S570-, R571-, L572-, P573-, P574-, K575-, S576-, V577-, I578-, C579-, S580-, L581-, T582-, N583-, H584-, I585-, I586-, D587-, Y588-, V589-, L590-, T591-, N592-, N593-, R594-, R595-, I596-, I597-, W598-, Q599-, S600-, Q601-, M602-, I603-, N604-, K605-, Y606-, V607-, L608-, L609-, L610-, D611-, P612-, S613-, F614-, Y615-, Y616-, R617-, F618-, R619-, N620-, V621-, I622-, E623-, N624-, K625-, L626-, D627-, Q628-, Y629-, N630-, N631-, R632-, Y633-, N634-, M635-, F636-, E637-, H638-, D639-, R640-, D641-, V642-, N643-, E644-, K645-, Y646-, G647-, K648-, V649-, L650-, H651-, D652-, L653-, D654-, T655-, Y656-, I657-, K658-, D659-, V660-, Q661-, V662-, L663-, K664-, S665-, T666-, S667-, I668-, T669-, N670-, N671-, I672-, T673-, L674-, Y675-, D676-, T677-, I678-, I679-, N680-, N681-, K682-, S683-, E684-, F685-, P686-, I687-, R688-, R689-, V690-, N691-, D692-, K693-, Q694-, L695-, I696-, N697-, L698-, I699-, K700-, S701-, N702-, T703-, Y704-, H705-, N706-, L707-, I708-, E709-, K710-, V711-, I712-, K713-, N714-, T715-, L716-, E717-, K718-, Y719-, T720-, L721-, T722-, N723-, I724-, V725-, L726-, E727-, Y728-, M729-, I730-, S731-, S732-, R733-, S734-, Q735-, S736-, S737-, Y738-, L739-, S740-, R741-, I742-, P743-, N744-, E745-, I746-, L747-, L748-, E749-, I750-, L751-, Y752-, K753-, L754-, D755-, M756-, Y757-, D758-, L759-, R760-, N761-, L762-, Y763-, T764-, R765-, Y766-, M767-, R768-, E769-, N770-, D771-, I772-, T773-, E774-, Y775-, H776-, I777-, E778-, N779-, T780-, R781-, S782-, V783-, S784-, T785-, Q786-, T787-, *788-; OPG209: G178X, *191X; OPG210: L733X, L734X, *1881X" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI07", - "node_attrs": { - "div": 61, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI07" - }, - "strain": { - "value": "ON682269" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "INMI-Pt2", - "node_attrs": { - "div": 61, - "author": { - "author": "Giombini,E., Gruber,C.E.M., Rueca,M., Gramigna,G., VIta,S., Carletti,F., D'Abramo,A., Lapa,D., Puro,V., Fabeni,L., Butera,O., Colavita,F., Meschi,S., Matusali,G., Specchiarello,E., Vairo,F., Vaia,F., Garbuglia,A.R., Nicastri,E., Antinori,A., GIrardi,E., Maggi,F.", - "value": "Giombini,E., Gruber,C.E.M., Rueca,M., Gramigna,G., VIta,S., Carletti,F., D'Abramo,A., Lapa,D., Puro,V., Fabeni,L., Butera,O., Colavita,F., Meschi,S., Matusali,G., Specchiarello,E., Vairo,F., Vaia,F., Garbuglia,A.R., Nicastri,E., Antinori,A., GIrardi,E., Maggi,F." - }, - "country": { - "value": "Italy" - }, - "date": { - "value": "2022-05-19" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "INMI-Pt2" - }, - "strain": { - "value": "ON745215" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A590-", - "T591-", - "-593A", - "-594T", - "-595A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "-196603A" - ] - } - } - }, - { - "name": "MpxV/Spain/MD-HGUGM-66649483/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Buenestado-Serrano,S., Palomino-Cabrera,R., Penas-Utrilla,D., Rodriguez-Grande,J., Sola Campoy,P., Perez-Lago,L., Rodriguez-Grande,C., Herranz Martin,M., Suarez,J., Catalan,P., Munoz,P., Garcia de Viedma,D.", - "value": "Buenestado-Serrano,S., Palomino-Cabrera,R., Penas-Utrilla,D., Rodriguez-Grande,J., Sola Campoy,P., Perez-Lago,L., Rodriguez-Grande,C., Herranz Martin,M., Suarez,J., Catalan,P., Munoz,P., Garcia de Viedma,D." - }, - "country": { - "value": "Spain" - }, - "date": { - "value": "2022-05-27" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "HGUGM, Microbial Genomics" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/Spain/MD-HGUGM-66649483/2022" - }, - "strain": { - "value": "ON745225" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G50151A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T" - ], - "OPG069": [ - "D56N" - ] - }, - "labels": { - "aa": "OPG069: D56N" - } - } - }, - { - "name": "INMI-Pt3", - "node_attrs": { - "div": 61, - "author": { - "author": "Rueca,M., Giombini,E., Gruber,C.E.M., Gramigna,G., Mazzotta,V., Carletti,F., Lapa,D., Pittalis,S., Puro,V., Fabeni,L., Butera,O., Colavita,F., Meschi,S., Matusali,G., Specchiarello,E., Vairo,F., Vaia,F., Nicastri,E., Antinori,A., Girardi,E., Maggi,F.", - "value": "Rueca,M., Giombini,E., Gruber,C.E.M., Gramigna,G., Mazzotta,V., Carletti,F., Lapa,D., Pittalis,S., Puro,V., Fabeni,L., Butera,O., Colavita,F., Meschi,S., Matusali,G., Specchiarello,E., Vairo,F., Vaia,F., Nicastri,E., Antinori,A., Girardi,E., Maggi,F." - }, - "country": { - "value": "Italy" - }, - "date": { - "value": "2022-05-19" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "INMI-Pt3" - }, - "strain": { - "value": "ON780016" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "-196603A" - ] - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-2975/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Knox,N., Duggan,A., Yadav,C., Hole,D., Haidl,E., Chapel,M., Jolly,G., Domselaar,G.V., Antonation,K., Leung,A., Fernando,L., Audet,J., Hagan,M., Graham,M., Griffiths,E., Safronetz,D., Charest,H., Levade,I., Fafard,J.", - "value": "Knox,N., Duggan,A., Yadav,C., Hole,D., Haidl,E., Chapel,M., Jolly,G., Domselaar,G.V., Antonation,K., Leung,A., Fernando,L., Audet,J., Hagan,M., Graham,M., Griffiths,E., Safronetz,D., Charest,H., Levade,I., Fafard,J." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-05-16" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-2975/2022" - }, - "strain": { - "value": "ON803443" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C23766T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T179065-", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-" - ], - "OPG039": [ - "W118*" - ] - }, - "labels": { - "aa": "OPG039: W118*" - } - } - }, - { - "name": "8887", - "node_attrs": { - "div": 63, - "author": { - "author": "de la Hoz-Sanchez,B., Lopez-Ortiz,M., Gutierrez-Arroyo,A., Roces-Alvarez,P., Lazaro-Peona,F., Dahdouh,E., Bloise,I., Garcia-Rodriguez,J., Mingorance,J.", - "value": "de la Hoz-Sanchez,B., Lopez-Ortiz,M., Gutierrez-Arroyo,A., Roces-Alvarez,P., Lazaro-Peona,F., Dahdouh,E., Bloise,I., Garcia-Rodriguez,J., Mingorance,J." - }, - "country": { - "value": "Spain" - }, - "date": { - "value": "2022-06-06" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Hospital Universitario La Paz, Microbiology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "8887" - }, - "strain": { - "value": "ON838939" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G90838A", - "G94328A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG111": [ - "D192N" - ] - }, - "labels": { - "aa": "OPG111: D192N" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI077", - "node_attrs": { - "div": 61, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI077" - }, - "strain": { - "value": "ON853679" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "WA-2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Fletcher,N., Gonzalez,G., Meredith,L., Purves,K., Carr,M., Dean,J., Keogan,B., Crowley,B., Lyons,F., O'Reilly,S., Gautier,V., Mallon,P., Gordon,S., Connell,J., De Gascun,C.F.", - "value": "Fletcher,N., Gonzalez,G., Meredith,L., Purves,K., Carr,M., Dean,J., Keogan,B., Crowley,B., Lyons,F., O'Reilly,S., Gautier,V., Mallon,P., Gordon,S., Connell,J., De Gascun,C.F." - }, - "country": { - "value": "Ireland" - }, - "date": { - "value": "2022-05-30" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University College Dublin, National Virus Reference Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "WA-2022" - }, - "strain": { - "value": "ON872184" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T48785C", - "G49636A", - "C50017T", - "T72809C", - "G178541A", - "A178772-", - "T178773-", - "A178774-", - "T178775-", - "A178776-", - "A178777-", - "C178778-", - "A178779-", - "C178780-", - "G178781-", - "A178782-", - "A178783-", - "T178784-", - "A178785-", - "T178786-", - "G178787-", - "T178788-", - "A178789-" - ], - "OPG068": [ - "G479E" - ], - "OPG069": [ - "T11I" - ], - "OPG092": [ - "K47E" - ] - }, - "labels": { - "aa": "OPG068: G479E; OPG069: T11I; OPG092: K47E" - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3486/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-06-08" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3486/2022" - }, - "strain": { - "value": "ON880518" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C134052T", - "C141458T", - "G179416A" - ], - "OPG208": [ - "E51K" - ] - }, - "labels": { - "aa": "OPG208: E51K" - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3086/2022", - "node_attrs": { - "div": 61, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-05-25" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3086/2022" - }, - "strain": { - "value": "ON880525" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/Spain/MD-HGUGM-6642566/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Palomino-Cabrera,R., Penas-Utrilla,D., Buenestado-Serrano,S., Perez-Lago,L., Herranz Martin,M., Veintimilla,C., Catalan,P., Munoz,P., Garcia de Viedma,D.", - "value": "Palomino-Cabrera,R., Penas-Utrilla,D., Buenestado-Serrano,S., Perez-Lago,L., Herranz Martin,M., Veintimilla,C., Catalan,P., Munoz,P., Garcia de Viedma,D." - }, - "country": { - "value": "Spain" - }, - "date": { - "value": "2022-06-21" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "HGUGM, Microbial Genomics" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/Spain/MD-HGUGM-6642566/2022" - }, - "strain": { - "value": "ON927243" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T179002-", - "G179003-", - "T179004-", - "A179005-", - "C179006-", - "A179007-", - "C179008-", - "G179009-", - "A179010-", - "T179011-", - "A179012-", - "C179013-", - "C179014-", - "A179015-", - "A179016-", - "T179017-", - "T179018-", - "T179019-", - "C187154T" - ] - } - } - }, - { - "name": "hMPXV/Austria/MUW1525179/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "country": { - "value": "Austria" - }, - "date": { - "value": "2022-06-10" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1525179/2022" - }, - "strain": { - "value": "OP019275" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "A107070C", - "C144546T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "G190319A", - "-196601A", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "MPXV_UK_2022_5", - "node_attrs": { - "div": 62, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-05-16" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_5" - }, - "strain": { - "value": "OP022170" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C178569T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T" - ] - } - } - }, - { - "name": "MPXV_UK_2022_6", - "node_attrs": { - "div": 61, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_6" - }, - "strain": { - "value": "OP022171" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179074-", - "T179075-", - "G179076-", - "-179092A" - ] - } - } - }, - { - "name": "MP01CHUAC", - "node_attrs": { - "div": 62, - "author": { - "author": "Aja-Macaya,P., Rumbo-Feal,S., Poza,M., Canizares,A., Vallejo,J.A., Bou,G.", - "value": "Aja-Macaya,P., Rumbo-Feal,S., Poza,M., Canizares,A., Vallejo,J.A., Bou,G." - }, - "country": { - "value": "Spain" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Biomedical research institute (INIBIC), Microbiology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MP01CHUAC" - }, - "strain": { - "value": "OP120937" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150330A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/ITM_pt_09/Belgium/2-Jun-2022", - "node_attrs": { - "div": 63, - "author": { - "author": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., den Bossche,D.V., Florence,E., Rezende,A.M., Vercauteren,K., Esbroeck,M.V., Bracke,S., Brosius,I., Soentjens,P.", - "value": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., den Bossche,D.V., Florence,E., Rezende,A.M., Vercauteren,K., Esbroeck,M.V., Bracke,S., Brosius,I., Soentjens,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-06-02" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/ITM_pt_09/Belgium/2-Jun-2022" - }, - "strain": { - "value": "OP144217" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T168120C", - "C173173-", - "G173174-", - "A173175-", - "C173176-", - "G178787-", - "T178788-", - "A178789-", - "T178790-", - "G178791-", - "A178792-", - "C178793-", - "G178794-", - "G178795-", - "A178796-", - "T178797-", - "G178798-", - "G178799-", - "G178800-", - "A178801-", - "A178802-", - "T178803-", - "T178804-", - "G178805-", - "G178806-", - "T178807-", - "A178808-", - "A178809-", - "C178810-", - "G178811-", - "A178812-", - "T178813-", - "G178814-", - "A178815-", - "C178816-", - "A178817-", - "G178818-", - "C188381T", - "-196603A" - ], - "OPG193": [ - "F263L" - ] - }, - "labels": { - "aa": "OPG193: F263L" - } - } - }, - { - "name": "MPXV_USA_2022_PA001", - "node_attrs": { - "div": 61, - "author": { - "author": "Gigante,C., Goldoft,M., Seabolt,M., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Holshue,M., Li,Y.", - "value": "Gigante,C., Goldoft,M., Seabolt,M., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Holshue,M., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_PA001" - }, - "strain": { - "value": "OP150926" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "hMpxV/Netherlands/NH-AUMC-0001/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Tutu van Furth AM, van der Kuip M, van Els AL, Fievez LC, van Rijckevorsel GG, van den Ouden A, Jonges M, Welkers MR, Welkers,M., Jonges,M.", - "value": "Tutu van Furth AM, van der Kuip M, van Els AL, Fievez LC, van Rijckevorsel GG, van den Ouden A, Jonges M, Welkers MR, Welkers,M., Jonges,M." - }, - "country": { - "value": "Netherlands" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/Netherlands/NH-AUMC-0001/2022" - }, - "strain": { - "value": "OP160532" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A148207T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "G191845A", - "A196604-" - ], - "OPG173": [ - "E57D" - ] - }, - "labels": { - "aa": "OPG173: E57D" - } - } - }, - { - "name": "MPXV_UK_2022_9000068", - "node_attrs": { - "div": 61, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-06-07" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000068" - }, - "strain": { - "value": "OP205074" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV_UK_2022_9000157", - "node_attrs": { - "div": 62, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-07-07" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000157" - }, - "strain": { - "value": "OP205115" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C78232T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV_UK_2022_9000167", - "node_attrs": { - "div": 62, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-06-30" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000167" - }, - "strain": { - "value": "OP205123" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C99954T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI262", - "node_attrs": { - "div": 62, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI262" - }, - "strain": { - "value": "OP215281" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G184945A" - ], - "OPG210": [ - "R1197K" - ] - }, - "labels": { - "aa": "OPG210: R1197K" - } - } - }, - { - "name": "MPX/PT0073/2022", - "node_attrs": { - "div": 63, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-07-27" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX/PT0073/2022" - }, - "strain": { - "value": "OP245327" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C7201T", - "C132698T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-4038/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Griffiths,E., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Griffiths,E., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-07-07" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-4038/2022" - }, - "strain": { - "value": "OP270028" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G43708A", - "C133362T", - "G134674A", - "G134755A", - "G148453A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG064": [ - "Q731*" - ], - "OPG174": [ - "R315C" - ] - }, - "labels": { - "aa": "OPG064: Q731*; OPG174: R315C" - } - } - }, - { - "name": "Monkeypox/PT0143/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-07-07" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0143/2022" - }, - "strain": { - "value": "OP324462" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C87017T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG108": [ - "D15N" - ] - }, - "labels": { - "aa": "OPG108: D15N" - } - } - }, - { - "name": "hMpxV/Netherlands/NH-AUMC-0060/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Welkers,M., Jonges,M., de Regt,M., Ooijevaar,R., Wagemakers,A.", - "value": "Welkers,M., Jonges,M., de Regt,M., Ooijevaar,R., Wagemakers,A." - }, - "country": { - "value": "Netherlands" - }, - "date": { - "value": "2022-08-05" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/Netherlands/NH-AUMC-0060/2022" - }, - "strain": { - "value": "OP341487" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C96773T", - "C109432T", - "C114985T", - "C142356T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG117": [ - "S242L" - ], - "OPG129": [ - "D525N" - ], - "OPG133": [ - "D238N" - ], - "OPG163": [ - "S52F" - ] - }, - "labels": { - "aa": "OPG117: S242L; OPG129: D525N; OPG133: D238N; OPG163: S52F" - } - } - }, - { - "name": "hMPXV-IHU00001", - "node_attrs": { - "div": 62, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "country": { - "value": "France" - }, - "date": { - "value": "2022-06-13" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPXV-IHU00001" - }, - "strain": { - "value": "OP382478" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C178006T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG205": [ - "S784F" - ] - }, - "labels": { - "aa": "OPG205: S784F" - } - } - }, - { - "name": "hMPXV-IHU00007", - "node_attrs": { - "div": 61, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "country": { - "value": "France" - }, - "date": { - "value": "2022-07-06" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPXV-IHU00007" - }, - "strain": { - "value": "OP382484" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "T133079-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "hMPXV-IHU00018", - "node_attrs": { - "div": 62, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "country": { - "value": "France" - }, - "date": { - "value": "2022-07-22" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPXV-IHU00018" - }, - "strain": { - "value": "OP382495" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G100498A", - "T179059-", - "A179060-", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-" - ], - "OPG119": [ - "R38K" - ] - }, - "labels": { - "aa": "OPG119: R38K" - } - } - }, - { - "name": "Monkeypox/PT0248/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-06-20" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0248/2022" - }, - "strain": { - "value": "OP414289" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C69477T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-196603A" - ] - } - } - }, - { - "name": "Monkeypox/PT0296/2022", - "node_attrs": { - "div": 63, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-06-08" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0296/2022" - }, - "strain": { - "value": "OP414330" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C110108T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A152274G" - ] - } - } - }, - { - "name": "MPX_h9DUQg_9000203", - "node_attrs": { - "div": 64, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_h9DUQg_9000203" - }, - "strain": { - "value": "OP415184" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C59862T", - "G83097A", - "G148496A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG105": [ - "D658N" - ] - }, - "labels": { - "aa": "OPG105: D658N" - } - } - }, - { - "name": "MPX_96X1Vd_9000218", - "node_attrs": { - "div": 61, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-03-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_96X1Vd_9000218" - }, - "strain": { - "value": "OP415196" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPX_rYdyAi_9000329", - "node_attrs": { - "div": 65, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_rYdyAi_9000329" - }, - "strain": { - "value": "OP415267" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C23567T", - "C67289T", - "G67527A", - "G77052A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG085": [ - "E415K" - ] - }, - "labels": { - "aa": "OPG085: E415K" - } - } - }, - { - "name": "hMPX/Human/USA/CA-LACPHL-MA00035/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Hemarajata,P., Green,N.M.", - "value": "Hemarajata,P., Green,N.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-13" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPX/Human/USA/CA-LACPHL-MA00035/2022" - }, - "strain": { - "value": "OP440550" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C1735T", - "T12827C", - "T12833A", - "T149447C", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "G195475A", - "-196603A" - ], - "OPG023": [ - "D23V", - "N25S" - ] - }, - "labels": { - "aa": "OPG023: D23V, N25S" - } - } - }, - { - "name": "hMPX/Human/USA/CA-LACPHL-MA00092/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-02" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPX/Human/USA/CA-LACPHL-MA00092/2022" - }, - "strain": { - "value": "OP442560" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T503-", - "G504-", - "G505-", - "C55472T", - "G55632A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "G167713A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ], - "OPG074": [ - "D552N" - ], - "OPG193": [ - "R127K" - ] - }, - "labels": { - "aa": "OPG074: D552N; OPG193: R127K" - } - } - }, - { - "name": "9000378", - "node_attrs": { - "div": 63, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000378" - }, - "strain": { - "value": "OP536758" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G43194A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "G182127A" - ], - "OPG210": [ - "D258N" - ] - }, - "labels": { - "aa": "OPG210: D258N" - } - } - }, - { - "name": "9000430", - "node_attrs": { - "div": 63, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000430" - }, - "strain": { - "value": "OP536802" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C87702T", - "G150484A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196603A" - ], - "OPG176": [ - "D226N" - ] - }, - "labels": { - "aa": "OPG176: D226N" - } - } - }, - { - "name": "Monkeypox/PT0506/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-16" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0506/2022" - }, - "strain": { - "value": "OP555579" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G569-", - "A570-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179074-", - "T179075-", - "G179076-", - "-179146A", - "-179147T", - "C179853T", - "A196524-", - "C196525-" - ] - } - } - }, - { - "name": "Slovenia-MPXV-27-2022", - "node_attrs": { - "div": 63, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "country": { - "value": "Slovenia" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Slovenia-MPXV-27-2022" - }, - "strain": { - "value": "OP605569" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G104565A", - "G130432A", - "T179166A", - "T179174G", - "A179178C", - "A179185G", - "A179187T", - "C179190G", - "T179197A", - "A179198T", - "A179200C", - "C179208A", - "A179209T", - "T179222G", - "A179223G", - "T179229G", - "A179236T", - "T179240C", - "T179248A", - "T179254A", - "G179256C", - "T179258G", - "A179261T", - "T179267C", - "G179269C", - "A179270G", - "A179272T", - "T179273C" - ], - "OPG123": [ - "S169F" - ], - "OPG208": [ - "M1T", - "D2R", - "I3S" - ] - }, - "labels": { - "aa": "OPG123: S169F; OPG208: M1T, D2R, I3S" - } - } - }, - { - "name": "Slovenia-MPXV-32-2022", - "node_attrs": { - "div": 67, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "country": { - "value": "Slovenia" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Slovenia-MPXV-32-2022" - }, - "strain": { - "value": "OP605574" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594A", - "-595T", - "A29748T", - "G72609A", - "G72610T", - "G72611T", - "T72614A", - "A72617C", - "C72618-", - "G72619-", - "T72620-", - "A72621-", - "T72622-", - "A120636-", - "T120637-", - "C120638-", - "T120639-", - "T120640-", - "T120641-", - "T120642-", - "T120643-", - "A120644-", - "T120645-", - "T120646-", - "A120647-", - "G120648-", - "T120649-", - "G120650-", - "G120651-", - "G120652-", - "C120653-", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "T196595-", - "T196596-", - "T196597-" - ], - "OPG047": [ - "*483K" - ], - "OPG092": [ - "N109X", - "T110-", - "C111G", - "K112X", - "P113N", - "*372X" - ], - "OPG138": [ - "M160X", - "P161-", - "T162-", - "N163-", - "K164-", - "K165-", - "I166X", - "*191X" - ] - }, - "labels": { - "aa": "OPG047: *483K; OPG092: N109X, T110-, C111G, K112X, P113N, *372X; OPG138: M160X, P161-, T162-, N163-, K164-, K165-, I166X, *191X" - } - } - }, - { - "name": "Slovenia-MPXV-33-2022", - "node_attrs": { - "div": 61, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "country": { - "value": "Slovenia" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Slovenia-MPXV-33-2022" - }, - "strain": { - "value": "OP605575" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A" - ] - } - } - }, - { - "name": "Slovenia-MPXV-41-2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "country": { - "value": "Slovenia" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Slovenia-MPXV-41-2022" - }, - "strain": { - "value": "OP605582" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C126-", - "-595T", - "C27187T" - ], - "OPG043": [ - "D257N" - ] - }, - "labels": { - "aa": "OPG043: D257N" - } - } - }, - { - "name": "Slovenia-MPXV-43-2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "country": { - "value": "Slovenia" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Slovenia-MPXV-43-2022" - }, - "strain": { - "value": "OP605584" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T10-", - "-595T", - "C8385T", - "T33995A", - "A86934G", - "G91904A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG052": [ - "M1L" - ] - }, - "labels": { - "aa": "OPG052: M1L" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI454", - "node_attrs": { - "div": 62, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI454" - }, - "strain": { - "value": "OP615328" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G158679A" - ] - } - } - }, - { - "name": "ANT_INS_MPX_0039_L", - "node_attrs": { - "div": 63, - "author": { - "author": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M.", - "value": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-07-29" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT_INS_MPX_0039_L" - }, - "strain": { - "value": "OP693649" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A267-", - "T268-", - "G269-", - "G127058A", - "G136194A", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG148": [ - "R358K" - ], - "OPG153": [ - "H492Y" - ] - }, - "labels": { - "aa": "OPG148: R358K; OPG153: H492Y" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI545", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI545" - }, - "strain": { - "value": "OP715825" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G28706A", - "C38873T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG045": [ - "P186L" - ], - "OPG056": [ - "M54I" - ] - }, - "labels": { - "aa": "OPG045: P186L; OPG056: M54I" - } - } - }, - { - "name": "Monkeypox virus/Human/USA/CA-LACPHL-MA00281/2022", - "node_attrs": { - "div": 68, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-10-18" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox virus/Human/USA/CA-LACPHL-MA00281/2022" - }, - "strain": { - "value": "OP748967" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G8172A", - "C28387T", - "G34143A", - "C77462T", - "G146006A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "G158190A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "G181578A" - ], - "OPG053": [ - "A183V" - ], - "OPG098": [ - "S188F" - ], - "OPG210": [ - "E75K" - ] - }, - "labels": { - "aa": "OPG053: A183V; OPG098: S188F; OPG210: E75K" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI593", - "node_attrs": { - "div": 61, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-10-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI593" - }, - "strain": { - "value": "OP837355" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00285/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-27" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00285/2022" - }, - "strain": { - "value": "OP890543" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C72191T", - "C89605T", - "G102186A", - "C137595T", - "G142636A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ], - "OPG092": [ - "E253K" - ], - "OPG121": [ - "E133K" - ], - "OPG153": [ - "A25T" - ] - }, - "labels": { - "aa": "OPG092: E253K; OPG121: E133K; OPG153: A25T" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00359/2022", - "node_attrs": { - "div": 61, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-11-05" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00359/2022" - }, - "strain": { - "value": "OP920697" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI688", - "node_attrs": { - "div": 65, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI688" - }, - "strain": { - "value": "OQ339207" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G3698A", - "A28524-", - "A28525-", - "G33851A", - "C128585T", - "C141143T", - "G150550-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150566A", - "-150567T" - ], - "OPG044": [ - "E145X", - "*150X" - ], - "OPG052": [ - "L49F" - ] - }, - "labels": { - "aa": "OPG044: E145X, *150X; OPG052: L49F" - } - } - }, - { - "name": "hMpxV/USA/CA-CDPH-1MPX1000091/2022", - "node_attrs": { - "div": 61, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-04" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/USA/CA-CDPH-1MPX1000091/2022" - }, - "strain": { - "value": "OQ348840" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T6975-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C" - ] - } - } - }, - { - "name": "hMPXV-CH-38292866/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Laubscher,F., Chudzinsk,V., Schibler,M., Kaiser,L., Renzoni,A.", - "value": "Laubscher,F., Chudzinsk,V., Schibler,M., Kaiser,L., Renzoni,A." - }, - "country": { - "value": "Switzerland" - }, - "date": { - "value": "2022-06-08" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University Hospitals of Geneva, Laboratory of Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPXV-CH-38292866/2022" - }, - "strain": { - "value": "OQ411312" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C87764T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG109": [ - "E562K" - ] - }, - "labels": { - "aa": "OPG109: E562K" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI716", - "node_attrs": { - "div": 67, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-10-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI716" - }, - "strain": { - "value": "OQ451901" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C2315T", - "G21250A", - "G40586A", - "C55859T", - "C93755T", - "G146821A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G160267A", - "G194895A" - ], - "OPG002": [ - "G146E" - ], - "OPG037": [ - "S395F" - ], - "OPG074": [ - "V423I" - ] - }, - "labels": { - "aa": "OPG002: G146E; OPG037: S395F; OPG074: V423I" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI717", - "node_attrs": { - "div": 67, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-11-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI717" - }, - "strain": { - "value": "OQ451902" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C3602T", - "C53342T", - "C124495T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G159789A", - "C170573T", - "G190695A", - "G193608A" - ], - "NBT03_gp174": [ - "E96K" - ], - "OPG003": [ - "E336K" - ], - "OPG071": [ - "R366K" - ], - "OPG198": [ - "S179L" - ] - }, - "labels": { - "aa": "NBT03_gp174: E96K; OPG003: E336K; OPG071: R366K; OPG198: S179L" - } - } - }, - { - "name": "hMpxV/USA/CACDPH1MPX1000174/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-12-23" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/USA/CACDPH1MPX1000174/2022" - }, - "strain": { - "value": "OQ547882" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C565-", - "A566-", - "T567-", - "C3850T", - "T6975-", - "T39315A", - "C132440T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "G193360A", - "G196581-", - "T196582-", - "C196583-" - ], - "OPG003": [ - "R253Q" - ], - "OPG057": [ - "D294V" - ] - }, - "labels": { - "aa": "OPG003: R253Q; OPG057: D294V" - } - } - }, - { - "name": "MPXV/Spain/HUNSC_ITER_0006b/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Munoz-Barrera,A., Ciuffreda,L., Alcoba-Florez,J., Rubio-Rodriguez,L.A., Rodriguez-Perez,H., Gil-Campesino,H., Garcia-Martinez de Artola,D., Salas-Hernandez,J., Rodriguez-Nunez,J., Inigo-Campos,A., Garcia-Olivares,V., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C.", - "value": "Munoz-Barrera,A., Ciuffreda,L., Alcoba-Florez,J., Rubio-Rodriguez,L.A., Rodriguez-Perez,H., Gil-Campesino,H., Garcia-Martinez de Artola,D., Salas-Hernandez,J., Rodriguez-Nunez,J., Inigo-Campos,A., Garcia-Olivares,V., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C." - }, - "country": { - "value": "Spain" - }, - "date": { - "value": "2022-07-01" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Spain/HUNSC_ITER_0006b/2022" - }, - "strain": { - "value": "OQ581848" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-133169T", - "-133170T", - "-133171T", - "-133172C", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C174264T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T" - ] - } - } - }, - { - "name": "INMI-22872022", - "node_attrs": { - "div": 63, - "author": { - "author": "Rueca,M., Tucci,F.G., Mazzotta,V., Gramigna,G., Gruber,C.E.M., Fabeni,L., Giombini,E., Matusali,G., Pinnetti,C., Mariano,A., Butera,O., Specchiarello,E., Mondi,A., Lanini,S., Carletti,F., Girardi,E., Vaia,F., Nicastri,E., Antinori,A., Maggi,F.", - "value": "Rueca,M., Tucci,F.G., Mazzotta,V., Gramigna,G., Gruber,C.E.M., Fabeni,L., Giombini,E., Matusali,G., Pinnetti,C., Mariano,A., Butera,O., Specchiarello,E., Mondi,A., Lanini,S., Carletti,F., Girardi,E., Vaia,F., Nicastri,E., Antinori,A., Maggi,F." - }, - "country": { - "value": "Italy" - }, - "date": { - "value": "2022-08-22" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute for Infectious Diseases \"L. Spallanzani\" - IRCCS, Laboratory of Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "INMI-22872022" - }, - "strain": { - "value": "OQ570421" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C106275T", - "G111562A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T" - ], - "OPG130": [ - "S114F" - ] - }, - "labels": { - "aa": "OPG130: S114F" - } - } - }, - { - "name": "MPXV/Spain/HUNSC_ITER_0007b/2022", - "node_attrs": { - "div": 63, - "author": { - "author": "Munoz-Barrera,A., Ciuffreda,L., Alcoba-Florez,J., Rubio-Rodriguez,L.A., Rodriguez-Perez,H., Gil-Campesino,H., Garcia-Martinez de Artola,D., Salas-Hernandez,J., Rodriguez-Nunez,J., Inigo-Campos,A., Garcia-Olivares,V., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C.", - "value": "Munoz-Barrera,A., Ciuffreda,L., Alcoba-Florez,J., Rubio-Rodriguez,L.A., Rodriguez-Perez,H., Gil-Campesino,H., Garcia-Martinez de Artola,D., Salas-Hernandez,J., Rodriguez-Nunez,J., Inigo-Campos,A., Garcia-Olivares,V., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C." - }, - "country": { - "value": "Spain" - }, - "date": { - "value": "2022-07-05" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Spain/HUNSC_ITER_0007b/2022" - }, - "strain": { - "value": "OQ581849" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A52777C", - "C150418T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T169409C", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C" - ], - "OPG071": [ - "Y554*" - ] - }, - "labels": { - "aa": "OPG071: Y554*" - } - } - }, - { - "name": "INMI-18982022", - "node_attrs": { - "div": 64, - "author": { - "author": "Rueca,M., Tucci,F.G., Mazzotta,V., Gramigna,G., Gruber,C.E.M., Fabeni,L., Giombini,E., Matusali,G., Pinnetti,C., Mariano,A., Butera,O., Specchiarello,E., Mondi,A., Lanini,S., Carletti,F., Girardi,E., Vaia,F., Nicastri,E., Antinori,A., Maggi,F.", - "value": "Rueca,M., Tucci,F.G., Mazzotta,V., Gramigna,G., Gruber,C.E.M., Fabeni,L., Giombini,E., Matusali,G., Pinnetti,C., Mariano,A., Butera,O., Specchiarello,E., Mondi,A., Lanini,S., Carletti,F., Girardi,E., Vaia,F., Nicastri,E., Antinori,A., Maggi,F." - }, - "country": { - "value": "Italy" - }, - "date": { - "value": "2022-08-16" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute for Infectious Diseases \"L. Spallanzani\" - IRCCS, Laboratory of Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "INMI-18982022" - }, - "strain": { - "value": "OQ627927" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C45203T", - "C88917T", - "C130606T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00470/2023", - "node_attrs": { - "div": 65, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-02-13" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00470/2023" - }, - "strain": { - "value": "OQ644776" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G2146A", - "A24345G", - "C39044T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "T170897-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "T187876C", - "C195064T" - ] - } - } - }, - { - "name": "MPXV/human/Taiwan/110-093354/2023", - "node_attrs": { - "div": 69, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "country": { - "value": "Taiwan" - }, - "date": { - "value": "2023-03-XX" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/human/Taiwan/110-093354/2023" - }, - "strain": { - "value": "OQ672580" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C39503G", - "G43620A", - "A44076G", - "G45563A", - "T69121C", - "T80764C", - "A130204G", - "A143123G", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG057": [ - "K231N" - ], - "OPG064": [ - "F608S" - ], - "OPG087": [ - "Y89H" - ], - "OPG104": [ - "N86D" - ], - "OPG164": [ - "T116A" - ] - }, - "labels": { - "aa": "OPG057: K231N; OPG064: F608S; OPG087: Y89H; OPG104: N86D; OPG164: T116A" - } - } - }, - { - "name": "MPXV/human/Taiwan/110-122438/2023", - "node_attrs": { - "div": 64, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "country": { - "value": "Taiwan" - }, - "date": { - "value": "2023-03-XX" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/human/Taiwan/110-122438/2023" - }, - "strain": { - "value": "OQ721951" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "T133084-", - "T133085-", - "T133086-", - "T133087-", - "T133088-", - "T149983A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G160358A", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A184479G", - "G193496T", - "A193498T", - "A193748G", - "T194019G", - "T194021A", - "G194086A" - ], - "OPG003": [ - "K298N", - "E299V", - "C473G", - "R495K" - ], - "OPG176": [ - "S59T" - ], - "OPG210": [ - "R1042G" - ] - }, - "labels": { - "aa": "OPG003: K298N, E299V, C473G, R495K; OPG176: S59T; OPG210: R1042G" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI860", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI860" - }, - "strain": { - "value": "OQ773479" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C3933T", - "C86851T", - "G150550-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG108": [ - "G70E" - ] - }, - "labels": { - "aa": "OPG108: G70E" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00485/2023", - "node_attrs": { - "div": 67, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-03-11" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00485/2023" - }, - "strain": { - "value": "OQ918696" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G30285A", - "G37487A", - "C71193T", - "G119839A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C161690T", - "C177865T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ], - "OPG047": [ - "P304S" - ], - "OPG137": [ - "E80K" - ], - "OPG188": [ - "S32F" - ], - "OPG205": [ - "S737F" - ] - }, - "labels": { - "aa": "OPG047: P304S; OPG137: E80K; OPG188: S32F; OPG205: S737F" - } - } - }, - { - "name": "case1_skin", - "node_attrs": { - "div": 65, - "author": { - "author": "Raymenants,J., Van Gestel,L., Coppens,J., de Block,T., Bangwen,E., Rutgers,J., Hens,M., De Vos,E., Coppens,S., Keyaerts,E., Andre,E., Rezende,A.M., Van Esbroeck,M., Vercauteren,K., Liesenborghs,L.", - "value": "Raymenants,J., Van Gestel,L., Coppens,J., de Block,T., Bangwen,E., Rutgers,J., Hens,M., De Vos,E., Coppens,S., Keyaerts,E., Andre,E., Rezende,A.M., Van Esbroeck,M., Vercauteren,K., Liesenborghs,L." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-09-06" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "case1_skin" - }, - "strain": { - "value": "OQ973327" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C111391T", - "C119654T", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "C152191T", - "T171948-", - "T171949-", - "C171950-", - "A171951-", - "C176178T", - "A178665-", - "C178666-", - "C178667-", - "T178668-", - "A178669-", - "A178670-", - "C178671-", - "T178672-", - "T178673-", - "C178674-", - "T178675-", - "G178676-", - "A178677-", - "A178678-", - "C178679-", - "T178680-", - "G178681-", - "G178682-", - "A178683-", - "A178684-", - "C178685-", - "T178686-", - "A178687-", - "T178688-", - "A178689-", - "A178690-", - "A178691-", - "T178692-", - "C178693-", - "C178694-", - "A178695-", - "G178696-" - ], - "OPG130": [ - "C171Y" - ], - "OPG137": [ - "S18L" - ], - "OPG199": [ - "F321-", - "I322X", - "*345X" - ], - "OPG205": [ - "H175Y" - ] - }, - "labels": { - "aa": "OPG130: C171Y; OPG137: S18L; OPG199: F321-, I322X, *345X; OPG205: H175Y" - } - } - }, - { - "name": "case6_air", - "node_attrs": { - "div": 64, - "author": { - "author": "Raymenants,J., Van Gestel,L., Coppens,J., de Block,T., Bangwen,E., Rutgers,J., Hens,M., De Vos,E., Coppens,S., Keyaerts,E., Andre,E., Rezende,A.M., Van Esbroeck,M., Vercauteren,K., Liesenborghs,L.", - "value": "Raymenants,J., Van Gestel,L., Coppens,J., de Block,T., Bangwen,E., Rutgers,J., Hens,M., De Vos,E., Coppens,S., Keyaerts,E., Andre,E., Rezende,A.M., Van Esbroeck,M., Vercauteren,K., Liesenborghs,L." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-09-01" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "case6_air" - }, - "strain": { - "value": "OQ973328" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G2615-", - "A2616-", - "T2617-", - "A2618-", - "G2619-", - "A2620-", - "C2621-", - "A2622-", - "A2623-", - "C2624-", - "A2625-", - "T2626-", - "A2627-", - "G2628-", - "A2629-", - "T2630-", - "T2631-", - "A2632-", - "C2633-", - "G2634-", - "G2635-", - "C2636-", - "T2637-", - "T2638-", - "C2639-", - "T2640-", - "G2641-", - "T2642-", - "A2643-", - "T2644-", - "T2645-", - "C2646-", - "G2647-", - "T2648-", - "T2649-", - "G2650-", - "T2651-", - "C2652-", - "T2653-", - "T2654-", - "T2655-", - "A2656-", - "C2657-", - "A2658-", - "C2659-", - "T2660-", - "C28168T", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "C147965T", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A178983-", - "A178984-", - "T178985-", - "A178986-", - "T178987-", - "G178988-", - "A178989-", - "T178990-", - "T178991-", - "T178992-", - "A178993-", - "A178994-", - "T178995-", - "T178996-", - "G178997-", - "A178998-", - "T178999-", - "T179000-", - "G179001-", - "T179002-", - "G179003-", - "T179004-", - "A179005-", - "C179006-", - "A179007-", - "C179008-", - "G179009-", - "A179010-", - "T179011-", - "A179012-", - "C179013-", - "C179014-", - "C179470T", - "A194550-", - "G194551-", - "T194552-", - "G194553-", - "T194554-", - "A194555-", - "A194556-", - "A194557-", - "G194558-", - "A194559-", - "C194560-", - "A194561-", - "A194562-", - "C194563-", - "G194564-", - "A194565-", - "A194566-", - "T194567-", - "A194568-", - "C194569-", - "A194570-", - "G194571-", - "A194572-", - "A194573-", - "G194574-", - "C194575-", - "C194576-", - "G194577-", - "T194578-", - "A194579-", - "A194580-", - "T194581-", - "C194582-", - "T194583-", - "A194584-", - "T194585-", - "G194586-", - "T194587-", - "T194588-", - "G194589-", - "T194590-", - "C194591-", - "T194592-", - "A194593-", - "T194594-", - "C194595-", - "A196604-" - ], - "OPG002": [ - "K31X", - "C32-", - "K33-", - "D34-", - "N35-", - "E36-", - "Y37-", - "R38-", - "S39-", - "R40-", - "N41-", - "L42-", - "C43-", - "C44-", - "L45-", - "S46X", - "*350X" - ], - "OPG172": [ - "S180F" - ], - "OPG208": [ - "P69S" - ] - }, - "labels": { - "aa": "OPG002: K31X, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46X, *350X; OPG172: S180F; OPG208: P69S" - } - } - }, - { - "name": "MPXV/UZ_REGA_74", - "node_attrs": { - "div": 62, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-06-03" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_74" - }, - "strain": { - "value": "OR035680" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A40037G", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_86", - "node_attrs": { - "div": 61, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-08-09" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_86" - }, - "strain": { - "value": "OR035692" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T150532-", - "T150533-", - "T150534-", - "T150535-", - "T150536-", - "T150537-", - "T150538-", - "T150539-", - "A150540-", - "T150541-", - "A150542-", - "G150543-", - "T150544-", - "A150545-", - "T150546-", - "G150547-", - "A150548-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_87", - "node_attrs": { - "div": 61, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-08-09" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_87" - }, - "strain": { - "value": "OR035693" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_89", - "node_attrs": { - "div": 61, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-08-09" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_89" - }, - "strain": { - "value": "OR035695" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_92", - "node_attrs": { - "div": 61, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-07-27" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_92" - }, - "strain": { - "value": "OR035698" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_93", - "node_attrs": { - "div": 62, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-06-30" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_93" - }, - "strain": { - "value": "OR035699" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C10015A", - "T155417-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_102", - "node_attrs": { - "div": 64, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-10-28" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_102" - }, - "strain": { - "value": "OR035708" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C60081T", - "C110147T", - "G162623A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG188": [ - "R343K" - ] - }, - "labels": { - "aa": "OPG188: R343K" - } - } - }, - { - "name": "MPXV/UZ_REGA_157/Belgium/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-07-27" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_157/Belgium/2022" - }, - "strain": { - "value": "OR086966" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "C168943T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "RNA", - "node_attrs": { - "div": 61, - "country": { - "value": "Slovakia" - }, - "date": { - "value": "2022-07-13" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "RNA" - }, - "strain": { - "value": "OX261748" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A196604-" - ] - } - } - }, - { - "name": "RNA", - "node_attrs": { - "div": 62, - "country": { - "value": "Slovakia" - }, - "date": { - "value": "2022-08-26" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "RNA" - }, - "strain": { - "value": "OX336004" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C94836T", - "T133078-", - "T133079-", - "T133080-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A196604-" - ] - } - } - }, - { - "name": "MPXV_IRBA22-14", - "node_attrs": { - "div": 61, - "author": { - "author": "Jarjaval,F., Nolent,F., Criqui,A., Chapus,C., Lamer,O., Ferraris,O., Gorge,O.", - "value": "Jarjaval,F., Nolent,F., Criqui,A., Chapus,C., Lamer,O., Ferraris,O., Gorge,O." - }, - "country": { - "value": "France" - }, - "date": { - "value": "2022-05-20" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IRBA, D.DNRBC/D.2MI/U.BACT" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_IRBA22-14" - }, - "strain": { - "value": "ON755040" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-" - ] - } - } - }, - { - "name": "MPX-42/Finland/2022", - "node_attrs": { - "div": 61, - "author": { - "author": "Kant,R., Smura,T., Vauhkonen,H., Vapalahti,O., Sironen,T.", - "value": "Kant,R., Smura,T., Vauhkonen,H., Vapalahti,O., Sironen,T." - }, - "country": { - "value": "Finland" - }, - "date": { - "value": "2022-05-31" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Helsinki, Department of Virology, Faculty of Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX-42/Finland/2022" - }, - "strain": { - "value": "ON782022" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - }, - { - "name": "MPX/UZ_REGA_3/Belgium/2022", - "node_attrs": { - "div": 61, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Sinnesael,R., Ysebaert,L., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Sinnesael,R., Ysebaert,L., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-05-27" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Rega Institute, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX/UZ_REGA_3/Belgium/2022" - }, - "strain": { - "value": "ON880419" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPX/UZ_REGA_4/Belgium/2022", - "node_attrs": { - "div": 61, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-05-27" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Rega Institute, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX/UZ_REGA_4/Belgium/2022" - }, - "strain": { - "value": "ON880420" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI113", - "node_attrs": { - "div": 61, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI113" - }, - "strain": { - "value": "ON929071" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "Monkeypox/PT0024/2022", - "node_attrs": { - "div": 61, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J.D., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Carvalho,I.L., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J.D., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Carvalho,I.L., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-05-19" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0024/2022" - }, - "strain": { - "value": "ON649720" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV_USA_2022_IL001", - "node_attrs": { - "div": 61, - "author": { - "author": "Gigante,C.M., Ghinai,I., Seabolt,M.H., Zhao,H., Wilkins,K., Respress,J., Howard,D., Batra,D., McCollum,A., Hutson,C., Davidson,W., Rao,A., Kerins,J., Li,Y.", - "value": "Gigante,C.M., Ghinai,I., Seabolt,M.H., Zhao,H., Wilkins,K., Respress,J., Howard,D., Batra,D., McCollum,A., Hutson,C., Davidson,W., Rao,A., Kerins,J., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_IL001" - }, - "strain": { - "value": "ON959131" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPX_96X1Vd_9000217", - "node_attrs": { - "div": 61, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-03-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_96X1Vd_9000217" - }, - "strain": { - "value": "OP415195" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV_USA_2022_MA001", - "node_attrs": { - "div": 61, - "author": { - "author": "Gigante,C.M., Smole,S., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Brown,C., Li,Y.", - "value": "Gigante,C.M., Smole,S., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Brown,C., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_MA001" - }, - "strain": { - "value": "ON563414" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV_ISR001_2022", - "node_attrs": { - "div": 61, - "author": { - "author": "Israeli,O., Guedj-Dana,Y., Lazar,S., Shifman,O., Erez,N., Weiss,S., Paran,N., Israely,T., Schuster,O., Zvi,A., Beth-Din,A., Cohen Gihon,I.", - "value": "Israeli,O., Guedj-Dana,Y., Lazar,S., Shifman,O., Erez,N., Weiss,S., Paran,N., Israely,T., Schuster,O., Zvi,A., Beth-Din,A., Cohen Gihon,I." - }, - "country": { - "value": "Israel" - }, - "date": { - "value": "2022-05-20" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_ISR001_2022" - }, - "strain": { - "value": "ON649879" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - }, - { - "name": "NODE_0000040", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "T133079-", - "G169928A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG197": [ - "D87N" - ] - }, - "labels": { - "aa": "OPG197: D87N" - } - }, - "children": [ - { - "name": "Monkeypox/BR0001/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Claro,I.M., de Lima,E.L., Romano,C.M., Candido,D.S., Lindoso,J.A.L., Barra,L.A.C., Borges,L.M.S., Medeiros,L.A., Tomishige,M.Y.S., Ramundo,M.S., Moutinho,T., da Silva,A.J.D., Rodrigues,C.C.M., de Azevedo,L.C.F., Villas-Boas,L.S., da Silva,C.A.M., Coletti,T.M., O'Toole,A., Quick,J., Loman,N., Rambaut,A., Faria,N.R., Figueiredo-Mello,C., Sabino,E.C.", - "value": "Claro,I.M., de Lima,E.L., Romano,C.M., Candido,D.S., Lindoso,J.A.L., Barra,L.A.C., Borges,L.M.S., Medeiros,L.A., Tomishige,M.Y.S., Ramundo,M.S., Moutinho,T., da Silva,A.J.D., Rodrigues,C.C.M., de Azevedo,L.C.F., Villas-Boas,L.S., da Silva,C.A.M., Coletti,T.M., O'Toole,A., Quick,J., Loman,N., Rambaut,A., Faria,N.R., Figueiredo-Mello,C., Sabino,E.C." - }, - "country": { - "value": "Brazil" - }, - "date": { - "value": "2022-06-07" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Imperial College London, School of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/BR0001/2022" - }, - "strain": { - "value": "ON751962" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T591-", - "A592-", - "-594T", - "G10118A", - "C15004T", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "T172973-", - "A172974-", - "T172975-", - "A172976-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-" - ], - "OPG021": [ - "E178K" - ] - }, - "labels": { - "aa": "OPG021: E178K" - } - } - }, - { - "name": "MPXV/UZ_REGA_144/Belgium/2022", - "node_attrs": { - "div": 67, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-07-05" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_144/Belgium/2022" - }, - "strain": { - "value": "OR086953" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C23345T", - "C23353T", - "C23356T", - "G58518A", - "G94041A" - ], - "OPG039": [ - "D255N", - "D256N" - ], - "OPG113": [ - "D771N" - ] - }, - "labels": { - "aa": "OPG039: D255N, D256N; OPG113: D771N" - } - } - } - ] - }, - { - "name": "NODE_0000041", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C65571T", - "G144988A", - "C156429T" - ] - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-3542/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Chapel,M., Tyler,A., Haidl,E., Domselaar,G.V., Antonation,K., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Jolly,G., Fafard,J., Charest,H., Levade,I.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Chapel,M., Tyler,A., Haidl,E., Domselaar,G.V., Antonation,K., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Jolly,G., Fafard,J., Charest,H., Levade,I." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-06-07" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3542/2022" - }, - "strain": { - "value": "OP013006" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3976/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Griffiths,E., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Griffiths,E., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-07-04" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3976/2022" - }, - "strain": { - "value": "OP270024" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C33082T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A196604-" - ], - "OPG049": [ - "D24N" - ] - }, - "labels": { - "aa": "OPG049: D24N" - } - } - } - ] - }, - { - "name": "NODE_0000042", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A28524-", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "C188252T", - "A196604-", - "A196605-" - ], - "OPG044": [ - "E145X", - "*150X" - ] - }, - "labels": { - "aa": "OPG044: E145X, *150X" - } - }, - "children": [ - { - "name": "hMPXV/Austria/MUW1533374/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "country": { - "value": "Austria" - }, - "date": { - "value": "2022-07-11" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1533374/2022" - }, - "strain": { - "value": "OP133004" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A322G", - "T450C", - "-179077A", - "-179090A", - "-179091T", - "-179092A", - "-179093T" - ] - } - } - }, - { - "name": "hMPXV/Austria/MUW1531848/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "country": { - "value": "Austria" - }, - "date": { - "value": "2022-07-05" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1531848/2022" - }, - "strain": { - "value": "OP133005" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G197058T", - "C197173G" - ] - } - } - } - ] - }, - { - "name": "NODE_0000043", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C12298T" - ] - } - }, - "children": [ - { - "name": "Monkeypox/PT0342/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-05-26" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0342/2022" - }, - "strain": { - "value": "OP414371" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_121", - "node_attrs": { - "div": 65, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-10-28" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_121" - }, - "strain": { - "value": "OR035727" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C32853T", - "G35385A", - "C169036T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG049": [ - "G100E" - ] - }, - "labels": { - "aa": "OPG049: G100E" - } - } - } - ] - }, - { - "name": "NODE_0000044", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G28490A", - "G102694A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG044": [ - "D134N" - ] - }, - "labels": { - "aa": "OPG044: D134N" - } - }, - "children": [ - { - "name": "hMPXV/Austria/MUW1538395/2022", - "node_attrs": { - "div": 63, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "country": { - "value": "Austria" - }, - "date": { - "value": "2022-08-01" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1538395/2022" - }, - "strain": { - "value": "OP422341" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "hMPXV/Austria/MUW1539124/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "country": { - "value": "Austria" - }, - "date": { - "value": "2022-08-02" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1539124/2022" - }, - "strain": { - "value": "OP422342" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C110960T" - ] - } - } - } - ] - }, - { - "name": "NODE_0000045", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C28104T", - "C28175T", - "G112246A", - "C125152T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C162012T" - ], - "OPG044": [ - "S5L" - ], - "OPG131": [ - "D103N" - ] - }, - "labels": { - "aa": "OPG044: S5L; OPG131: D103N" - } - }, - "children": [ - { - "name": "Monkeypox/PT0563/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-09-05" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0563/2022" - }, - "strain": { - "value": "OP555634" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0576/2022", - "node_attrs": { - "div": 68, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-09-05" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0576/2022" - }, - "strain": { - "value": "OP555647" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C46132T", - "A153083G" - ], - "OPG065": [ - "D118N" - ], - "OPG180": [ - "K131R" - ] - }, - "labels": { - "aa": "OPG065: D118N; OPG180: K131R" - } - } - } - ] - }, - { - "name": "NODE_0000046", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G184141A" - ], - "OPG210": [ - "G929D" - ] - }, - "labels": { - "aa": "OPG210: G929D" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/ON/RKI448", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI448" - }, - "strain": { - "value": "OP615324" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G183382A" - ], - "OPG210": [ - "R676Q" - ] - }, - "labels": { - "aa": "OPG210: R676Q" - } - } - }, - { - "name": "RNA", - "node_attrs": { - "div": 63, - "country": { - "value": "Slovakia" - }, - "date": { - "value": "2022-07-25" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "RNA" - }, - "strain": { - "value": "OX291780" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G67955A", - "A173274-", - "T173275-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A196604-" - ], - "OPG085": [ - "P193S" - ] - }, - "labels": { - "aa": "OPG085: P193S" - } - } - } - ] - }, - { - "name": "NODE_0000047", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C36405T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG055": [ - "A227T" - ] - }, - "labels": { - "aa": "OPG055: A227T" - } - }, - "children": [ - { - "name": "VAC_INS_MPX_1054_L", - "node_attrs": { - "div": 67, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-10-25" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "VAC_INS_MPX_1054_L" - }, - "strain": { - "value": "OP837473" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C33082T", - "C40849T", - "G68103A", - "G117233A", - "C180361T", - "A196376-", - "T196377-", - "C196378-" - ], - "OPG049": [ - "D24N" - ], - "OPG060": [ - "E112K" - ] - }, - "labels": { - "aa": "OPG049: D24N; OPG060: E112K" - } - } - }, - { - "name": "NY-NYCPHL-000100", - "node_attrs": { - "div": 62, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-22" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000100" - }, - "strain": { - "value": "OQ469035" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150567A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - } - ] - }, - { - "name": "NODE_0000048", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C100867T" - ], - "OPG119": [ - "S161L" - ], - "OPG120": [ - "M294I" - ] - }, - "labels": { - "aa": "OPG119: S161L; OPG120: M294I" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_IL0029", - "node_attrs": { - "div": 63, - "author": { - "author": "Gigante,C., Ghinai,I., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Kerins,J., Li,Y.", - "value": "Gigante,C., Ghinai,I., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Kerins,J., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_IL0029" - }, - "strain": { - "value": "OQ054223" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G46279A", - "A196604-" - ], - "OPG065": [ - "P69S" - ] - }, - "labels": { - "aa": "OPG065: P69S" - } - } - }, - { - "name": "NY-NYCPHL-001186", - "node_attrs": { - "div": 67, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-01-03" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-001186" - }, - "strain": { - "value": "OQ419086" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C1008T", - "G79978A", - "G112742A", - "C118609T", - "G128255A", - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "C185113T", - "G196202A" - ], - "OPG001": [ - "D190N" - ], - "OPG136": [ - "A327T" - ], - "OPG210": [ - "S1253L" - ] - }, - "labels": { - "aa": "OPG001: D190N; OPG136: A327T; OPG210: S1253L" - } - } - } - ] - }, - { - "name": "NODE_0000049", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C54262T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - }, - "children": [ - { - "name": "hMpxV/USA/CA-CDPH-1000090/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., Bell,J., Hacker,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-11-08" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/USA/CA-CDPH-1000090/2022" - }, - "strain": { - "value": "OQ121043" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C22880T", - "G74672A", - "C76556T", - "C156732T", - "G178981-", - "T178982-", - "A178983-", - "A178984-", - "T178985-", - "A178986-", - "T178987-", - "G178988-", - "A178989-", - "T178990-", - "T178991-", - "T178992-", - "A178993-", - "A178994-", - "T178995-", - "T178996-", - "G178997-", - "A178998-", - "T178999-", - "T179000-", - "G179001-", - "T179002-", - "G179003-", - "T179004-", - "A179005-", - "C179006-", - "A179007-", - "C179008-", - "G179009-", - "A179010-", - "T179011-", - "A179012-", - "C179013-", - "C179014-", - "A179015-", - "A179016-", - "T179017-", - "T179018-", - "T179019-", - "G179020-", - "T179021-", - "C179022-", - "G179023-", - "A179024-", - "G179025-", - "T179026-", - "A179027-", - "T179028-", - "G179029-", - "A179030-", - "A179031-", - "T179032-", - "A179033-", - "C179034-", - "G179035-", - "G179036-", - "A179037-", - "G179038-", - "T179039-", - "A179040-", - "C179041-", - "A179042-", - "A179043-", - "A179044-", - "C179045-", - "A179046-", - "T179047-", - "A179048-", - "A179049-", - "A179050-", - "C179051-", - "T179052-", - "G179053-", - "A179054-", - "A179055-", - "G179056-", - "T179057-", - "T179058-", - "T179059-", - "A179060-", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-" - ], - "OPG038": [ - "E94K" - ], - "OPG094": [ - "R298K" - ], - "OPG097": [ - "R107K" - ] - }, - "labels": { - "aa": "OPG038: E94K; OPG094: R298K; OPG097: R107K" - } - } - }, - { - "name": "RNA", - "node_attrs": { - "div": 66, - "country": { - "value": "Slovakia" - }, - "date": { - "value": "2022-08-01" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "RNA" - }, - "strain": { - "value": "OX291694" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C15311T", - "C28887T", - "G81015T", - "G141131A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A196604-" - ], - "OPG045": [ - "E126K" - ], - "OPG104": [ - "T2K" - ] - }, - "labels": { - "aa": "OPG045: E126K; OPG104: T2K" - } - } - } - ] - }, - { - "name": "NODE_0000050", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G106113A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "C189810T" - ] - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00412/2023", - "node_attrs": { - "div": 67, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-01-05" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00412/2023" - }, - "strain": { - "value": "OQ503800" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C22664T", - "G25294A", - "C25308T", - "G40111A", - "T179174-", - "T179175-" - ], - "OPG038": [ - "D166N" - ], - "OPG040": [ - "S62L" - ], - "OPG057": [ - "H29Y" - ] - }, - "labels": { - "aa": "OPG038: D166N; OPG040: S62L; OPG057: H29Y" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00489/2023", - "node_attrs": { - "div": 66, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-02-20" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00489/2023" - }, - "strain": { - "value": "OQ918700" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G66587A", - "G143857A", - "C144237T", - "-150567T" - ], - "OPG165": [ - "S241L" - ] - }, - "labels": { - "aa": "OPG165: S241L" - } - } - } - ] - }, - { - "name": "NODE_0000053", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G174678A" - ] - } - }, - "children": [ - { - "name": "Monkeypox/PT0468/2022", - "node_attrs": { - "div": 63, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-05" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0468/2022" - }, - "strain": { - "value": "OP555547" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T553-", - "T554-", - "C50801T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T196405-", - "G196406-" - ], - "OPG070": [ - "S71L" - ] - }, - "labels": { - "aa": "OPG070: S71L" - } - } - }, - { - "name": "hMPX/USA/CA-LACPHL-MA00174/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-03" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPX/USA/CA-LACPHL-MA00174/2022" - }, - "strain": { - "value": "OP580607" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G13224A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "C184442T" - ], - "OPG024": [ - "S2L" - ] - }, - "labels": { - "aa": "OPG024: S2L" - } - } - }, - { - "name": "MPXV/UZ_REGA_201/Belgium/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-08-03" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_201/Belgium/2022" - }, - "strain": { - "value": "OR087010" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - } - ] - }, - { - "name": "NODE_0000054", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C127215T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG149": [ - "S7L" - ] - }, - "labels": { - "aa": "OPG149: S7L" - } - }, - "children": [ - { - "name": "MPXV/UZ_REGA_99", - "node_attrs": { - "div": 63, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-06-02" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_99" - }, - "strain": { - "value": "OR035705" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C142797T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG164": [ - "S7L" - ] - }, - "labels": { - "aa": "OPG164: S7L" - } - } - }, - { - "name": "NODE_0000055", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G57907A", - "C105991T", - "C114157T", - "G175662A" - ], - "OPG077": [ - "S226L" - ], - "OPG133": [ - "E514K" - ], - "OPG205": [ - "E3K" - ] - }, - "labels": { - "aa": "OPG077: S226L; OPG133: E514K; OPG205: E3K" - } - }, - "children": [ - { - "name": "LBMB-UTP_MP-007_TOL", - "node_attrs": { - "div": 66, - "author": { - "author": "Anacona,J.D., Lopez,P.A., Orjuela,M., Tabares,F.A., Zuluaga-Velez,A., Sepulveda-Arias,J.C.", - "value": "Anacona,J.D., Lopez,P.A., Orjuela,M., Tabares,F.A., Zuluaga-Velez,A., Sepulveda-Arias,J.C." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-09-14" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "LBMB-UTP_MP-007_TOL" - }, - "strain": { - "value": "OQ148465" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-" - ] - } - } - }, - { - "name": "LBMB-UTP_MP-009_TOL", - "node_attrs": { - "div": 66, - "author": { - "author": "Orjuela,M., Tabares,F.A., Anacona,J.D., Lopez,P.A., Zuluaga-Velez,A., Sepulveda-Arias,J.C.", - "value": "Orjuela,M., Tabares,F.A., Anacona,J.D., Lopez,P.A., Zuluaga-Velez,A., Sepulveda-Arias,J.C." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-09-13" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "LBMB-UTP_MP-009_TOL" - }, - "strain": { - "value": "OQ148466" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000056", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G177009A" - ], - "OPG205": [ - "E452K" - ] - }, - "labels": { - "aa": "OPG205: E452K" - } - }, - "children": [ - { - "name": "NODE_0000057", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A467-", - "T468-", - "A469-", - "C117119T", - "C118453T", - "G137276A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ], - "OPG136": [ - "E379K" - ], - "OPG153": [ - "S131F" - ] - }, - "labels": { - "aa": "OPG136: E379K; OPG153: S131F" - } - }, - "children": [ - { - "name": "MPX/Human/USA/CA-LACPHL-MA00254/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-10-11" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX/Human/USA/CA-LACPHL-MA00254/2022" - }, - "strain": { - "value": "OP722513" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G28136-", - "A28137-", - "T28138-", - "G87430A" - ], - "OPG044": [ - "D16-" - ], - "OPG109": [ - "S673L" - ] - }, - "labels": { - "aa": "OPG044: D16-; OPG109: S673L" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00420/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-12-01" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00420/2022" - }, - "strain": { - "value": "OQ503813" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000058", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C17048T", - "G74360A", - "G93828A" - ], - "OPG029": [ - "D8N" - ], - "OPG094": [ - "R194H" - ], - "OPG113": [ - "E700K" - ] - }, - "labels": { - "aa": "OPG029: D8N; OPG094: R194H; OPG113: E700K" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI633", - "node_attrs": { - "div": 66, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-11-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI633" - }, - "strain": { - "value": "OQ159028" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C41131T" - ], - "OPG060": [ - "E18K" - ] - }, - "labels": { - "aa": "OPG060: E18K" - } - } - }, - { - "name": "MPXV/PT0626/2023", - "node_attrs": { - "div": 72, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2023-03-21" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/PT0626/2023" - }, - "strain": { - "value": "OQ735077" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A571-", - "G572-", - "C10929T", - "C22179T", - "G39515A", - "G77076A", - "G129659A", - "C129949T", - "G139167A", - "G196594-", - "T196595-", - "-196601A" - ], - "OPG023": [ - "E658K" - ], - "OPG151": [ - "E246K" - ] - }, - "labels": { - "aa": "OPG023: E658K; OPG151: E246K" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000059", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.20" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G53326A", - "T133078-", - "C164385T", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "C187620T" - ] - }, - "labels": { - "clade": "B.1.20" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_TX0040", - "node_attrs": { - "div": 64, - "author": { - "author": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Sheth,M.R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y.", - "value": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Sheth,M.R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-10-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_TX0040" - }, - "strain": { - "value": "OQ320441" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.20" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196603A" - ] - } - } - }, - { - "name": "NODE_0000060", - "node_attrs": { - "div": 68, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.20" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "T597-", - "T598-", - "T599-", - "T600-", - "C20453T", - "-133078T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T164946C", - "-173292A", - "-173293T", - "G177398A", - "C177899T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A196604-", - "A196605-", - "A196606-", - "A196607-", - "A196608-" - ] - } - }, - "children": [ - { - "name": "hMpxV/USA/IL-RIPHL-MPXV-052-0038/2023", - "node_attrs": { - "div": 68, - "author": { - "author": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S.", - "value": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-05-11" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/USA/IL-RIPHL-MPXV-052-0038/2023" - }, - "strain": { - "value": "OR160419" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.20" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "hMpxV/USA/IL-RIPHL-MPXV-050-0060/2023", - "node_attrs": { - "div": 68, - "author": { - "author": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S.", - "value": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-05-31" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/USA/IL-RIPHL-MPXV-050-0060/2023" - }, - "strain": { - "value": "OR257449" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.20" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "hMpxV/USA/IL-RIPHL-MPXV-050-0068/2023", - "node_attrs": { - "div": 72, - "author": { - "author": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S.", - "value": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-06-14" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/USA/IL-RIPHL-MPXV-050-0068/2023" - }, - "strain": { - "value": "OR257450" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.20" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C2313T", - "T117118C", - "G170233A", - "G189274A", - "G194897A" - ], - "OPG002": [ - "D147N" - ], - "OPG005": [ - "V26I" - ], - "OPG136": [ - "M824V" - ], - "OPG198": [ - "D66N" - ] - }, - "labels": { - "aa": "OPG002: D147N; OPG005: V26I; OPG136: M824V; OPG198: D66N" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000094", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C148268T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - }, - "children": [ - { - "name": "MPXV_IRBA22-11", - "node_attrs": { - "div": 62, - "author": { - "author": "Jarjaval,F., Nolent,F., Criqui,A., Chapus,C., Lamer,O., Ferraris,O., Gorge,O.", - "value": "Jarjaval,F., Nolent,F., Criqui,A., Chapus,C., Lamer,O., Ferraris,O., Gorge,O." - }, - "country": { - "value": "France" - }, - "date": { - "value": "2022-05-19" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IRBA, D.DNRBC/D.2MI/U.BACT" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_IRBA22-11" - }, - "strain": { - "value": "ON755039" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-" - ] - } - } - }, - { - "name": "NODE_0000096", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.19" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G9963A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG021": [ - "R126K" - ] - }, - "labels": { - "aa": "OPG021: R126K", - "clade": "B.1.19" - } - }, - "children": [ - { - "name": "ID6821", - "node_attrs": { - "div": 63, - "author": { - "author": "Viscardi,M., Cozzolino,L., De Martinis,C., Cardillo,L., Fusco,G.", - "value": "Viscardi,M., Cozzolino,L., De Martinis,C., Cardillo,L., Fusco,G." - }, - "country": { - "value": "Italy" - }, - "date": { - "value": "2022-06-21" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Istituto Zooprofilattico Sperimentale del Mezzogiorno, Hanimal Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ID6821" - }, - "strain": { - "value": "OP838893" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.19" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A4728-", - "A4729-", - "C4730-", - "T4731-", - "A4732-", - "A4733-", - "C4734-", - "T4735-", - "T4736-", - "A4737-", - "T4738-", - "G4739-", - "T133100-", - "T133101-", - "T133102-", - "C133103-", - "G133104-", - "A133105-", - "A133106-", - "T133107-", - "T133108-", - "C133109-", - "A133110-", - "C133111-", - "G133112-", - "A140105-", - "T140106-", - "A140107-", - "A140108-", - "C140109-", - "A140110-", - "A140111-", - "T140112-", - "T140113-", - "A157667-", - "A157668-", - "T157669-", - "C157670-", - "A157671-", - "A157672-", - "T157673-", - "G157674-", - "A157675-", - "T157676-", - "A157677-", - "A157678-", - "A157679-", - "A157680-", - "A157681-", - "T157682-", - "T157683-", - "T157684-", - "T157685-", - "T163214-", - "C163215-", - "T163216-", - "T163217-", - "A163218-", - "T163219-", - "A163220-", - "T163221-", - "A163408-", - "A163409-", - "T163410-", - "T163411-", - "C163412-", - "T163413-", - "T163414-", - "C163415-", - "C163416-", - "G174519-", - "A174520-", - "T174521-", - "G174522-", - "A174523-", - "A174524-", - "G174525-", - "A174526-", - "T174527-", - "G174528-", - "A174529-", - "A174530-", - "A180469-", - "A180470-", - "A180471-", - "A180472-", - "A180473-", - "A180474-", - "T180475-", - "T180476-", - "T181102-", - "A181103-", - "T181104-", - "A181105-", - "T181106-", - "T181107-", - "C181108-", - "C181109-", - "T181110-", - "T192477-", - "T192478-", - "A192479-", - "G192480-", - "T192481-", - "T192482-", - "A192483-", - "A192484-", - "G192485-", - "T192486-", - "C192487-", - "A192488-" - ], - "OPG159": [ - "N113X", - "N114-", - "N115-", - "Y116X", - "*146X" - ], - "OPG189": [ - "N26-", - "S27-", - "S28-" - ] - }, - "labels": { - "aa": "OPG159: N113X, N114-, N115-, Y116X, *146X; OPG189: N26-, S27-, S28-" - } - } - }, - { - "name": "NODE_0000097", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.19" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150003A" - ] - } - }, - "children": [ - { - "name": "MPXV-1047", - "node_attrs": { - "div": 68, - "author": { - "author": "Zeggagh,J., Ferraris,O., Salmona,M., Tarantola,A., Molina,J.M., Delaugerre,C.", - "value": "Zeggagh,J., Ferraris,O., Salmona,M., Tarantola,A., Molina,J.M., Delaugerre,C." - }, - "country": { - "value": "France" - }, - "date": { - "value": "2022-06-07" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Hopital Saint Louis, Paris" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV-1047" - }, - "strain": { - "value": "OQ172215" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.19" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A2591G", - "A31053G", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "T133084-", - "-133164C", - "-133165A", - "-133166A", - "-133167T", - "-133168C", - "-133169T", - "-133173T", - "T133633-", - "G150577-", - "A150578-", - "T150579-", - "A150580-", - "T150581-", - "G150582-", - "A150583-", - "T150584-", - "G150620-", - "G150621-", - "A150622-", - "T150623-", - "A150624-", - "T150625-", - "G150626-", - "A150627-", - "T150628-", - "A150629-", - "A152668-", - "T152680-", - "T155897A", - "C173533A", - "A179077T", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "A179140T", - "A179142T", - "A179144T", - "C179145T", - "A179146T", - "T194619C", - "T194627G" - ], - "OPG002": [ - "F54S", - "C57G" - ], - "OPG047": [ - "C48R" - ] - }, - "labels": { - "aa": "OPG002: F54S, C57G; OPG047: C48R" - } - } - }, - { - "name": "9000406", - "node_attrs": { - "div": 65, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000406" - }, - "strain": { - "value": "OP536782" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.19" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C74417T" - ], - "OPG094": [ - "S213L" - ] - }, - "labels": { - "aa": "OPG094: S213L" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000061", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C112408T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A" - ], - "OPG131": [ - "L157F" - ] - }, - "labels": { - "aa": "OPG131: L157F" - } - }, - "children": [ - { - "name": "19012023_anal", - "node_attrs": { - "div": 64, - "author": { - "author": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K.", - "value": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2023-01-19" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "19012023_anal" - }, - "strain": { - "value": "OQ672571" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G69989A", - "C117978T", - "T145492-", - "G145493-", - "A145494-", - "A145495-", - "G145496-", - "A145497-", - "A145498-", - "A145499-", - "T145500-", - "A145501-", - "A145502-", - "T145503-", - "T145504-", - "T145505-", - "C145506-", - "T145507-", - "A145508-", - "C145509-", - "A145646-", - "C145647-", - "A145648-", - "T145649-", - "T145650-", - "A145651-", - "G145652-", - "T145653-", - "A145654-", - "G145655-", - "T145656-", - "A145657-", - "T145658-", - "G145659-", - "C145660-", - "G145661-", - "G145662-", - "A145663-", - "A145664-", - "C145665-", - "C145666-", - "A145667-", - "A145668-", - "T145669-", - "A145670-", - "A145671-", - "C145672-", - "G145673-", - "G145674-", - "A145675-", - "A145676-", - "A145677-", - "T145678-", - "C145679-", - "C145680-", - "C145681-", - "A145682-", - "A145683-", - "A145684-", - "T145685-", - "G145686-", - "T145687-", - "T145688-", - "G145689-", - "G145690-", - "A145691-", - "A145692-", - "A145693-", - "A145694-", - "T145695-", - "A145696-", - "G145697-", - "A145698-", - "C145699-", - "G145700-", - "G145701-", - "T145702-", - "T145703-", - "C145704-", - "A145705-", - "T145706-", - "A145707-", - "C145708-", - "T145709-", - "A145710-", - "C145711-", - "C145712-", - "C145713-", - "A145714-", - "A145715-", - "A145716-", - "A145717-", - "C145718-", - "A145719-", - "T145720-", - "A145721-", - "T145722-", - "A145723-", - "G145724-", - "G145725-", - "T145726-", - "A145727-", - "G145728-", - "A145729-", - "G145730-", - "G145731-", - "A145732-", - "T145733-", - "A145734-", - "C145735-", - "G145736-", - "A145737-", - "T145738-", - "C145739-", - "A145740-", - "T145741-", - "C145742-", - "A145743-", - "A145744-", - "A145745-", - "A145746-", - "T145747-", - "A145748-", - "G145749-", - "C145750-", - "A145751-", - "A145752-", - "A145753-", - "G145754-", - "T145755-", - "A145756-", - "A145757-", - "C145758-", - "G145759-", - "A145760-", - "T145761-", - "A145762-", - "A145763-", - "T145764-", - "C145765-", - "A145766-", - "G145767-", - "T145768-", - "C145769-", - "A145770-", - "C145771-", - "A145772-", - "A145773-", - "T145774-", - "G145775-", - "A145776-", - "A145777-", - "T145778-", - "G145779-", - "T145780-", - "G145781-", - "T145782-", - "A145783-", - "C145784-", - "T145785-", - "A145786-", - "T145787-", - "C145788-", - "C145789-", - "G145790-", - "A145791-", - "C145792-", - "A145793-", - "T145794-", - "A145795-", - "A145796-", - "A145797-", - "C145798-", - "A145799-", - "T145800-", - "A145801-", - "T145802-", - "A145803-", - "A145804-", - "A145805-", - "A145806-", - "A145807-", - "G145808-", - "A145809-", - "A145810-", - "G145811-", - "G145812-", - "A145813-", - "A145814-", - "T145815-", - "T145816-", - "A145817-", - "A145818-", - "A145819-", - "C145820-", - "G145821-", - "A145822-", - "T145823-", - "G145824-", - "G145825-", - "A145826-", - "G145827-", - "A145828-", - "A145829-", - "G145830-", - "A145831-", - "T145832-", - "T145833-", - "T145834-", - "G145835-", - "A145836-", - "C145837-", - "G145838-", - "G145839-", - "A145840-", - "C145841-", - "C145842-", - "A145843-", - "T145844-", - "G145845-", - "T145846-", - "G145847-", - "G145848-", - "T145849-", - "T145850-", - "A145851-", - "T145852-", - "G145853-", - "A145854-", - "T145855-", - "T145856-", - "A145857-", - "A145858-", - "A145859-", - "C145860-", - "G145861-", - "A145862-", - "G145863-", - "T145864-", - "T145865-", - "A145866-", - "A145867-", - "G145868-", - "T145869-", - "T145870-", - "T145871-", - "T145872-", - "T145873-", - "T145874-", - "A145875-", - "A145876-", - "G145877-", - "A145878-", - "A145879-", - "G145880-", - "C145881-", - "C145882-", - "T145883-", - "T145884-", - "A145885-", - "G145886-", - "A145887-", - "A169725-", - "T169726-", - "T178558-", - "G178559-", - "A178560-", - "T178561-", - "T178562-", - "A178563-", - "T178564-", - "A178565-", - "C178566-", - "A178567-", - "T178568-", - "C178569-", - "G178570-", - "G178571-", - "T178572-", - "A178573-", - "C178574-", - "A178575-" - ], - "OPG089": [ - "A42T" - ], - "OPG136": [ - "R537K" - ], - "OPG197": [ - "D19X", - "*101X" - ] - }, - "labels": { - "aa": "OPG089: A42T; OPG136: R537K; OPG197: D19X, *101X" - } - } - }, - { - "name": "NODE_0000062", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A47741-", - "A49707-", - "A62106-", - "T62107-", - "A62108-", - "A62110-", - "T62111-", - "A62112-", - "A62113-", - "A62114-", - "A62116-", - "T62118-", - "T62121-", - "A62122-", - "T62123-", - "A62124-", - "T62125-", - "A62126-", - "T62127-", - "T62128-", - "T62129-", - "A62131-", - "A62132-", - "A62133-", - "A62134-", - "T62135-", - "T62138-", - "T62139-", - "A62140-", - "T62144-", - "T62145-", - "A62148-", - "T62164-", - "A62167-", - "T62168-", - "T62169-", - "T62171-", - "A62173-", - "A62174-", - "T62175-", - "A62176-", - "T62177-", - "A62178-", - "T62179-", - "A62181-", - "T62182-", - "T62183-", - "A62184-", - "A62187-", - "T62188-", - "T62189-", - "T62190-", - "A62191-", - "A62192-", - "T62194-", - "T62197-", - "T62198-", - "A62200-", - "T62202-", - "A62203-", - "T62204-", - "A62206-", - "T62207-", - "T62213-", - "A62217-", - "A62219-", - "A62220-", - "A62221-", - "T62222-", - "T62223-", - "A62224-", - "A62227-", - "T62228-", - "A62230-", - "A62231-", - "A62232-", - "A62233-", - "A62236-", - "T62237-", - "T62238-", - "A62239-", - "A62240-", - "T62241-", - "A62242-", - "A62244-", - "T62246-", - "T62247-", - "A62248-", - "T62249-", - "A62252-", - "A62254-", - "T62255-", - "A62259-", - "T62261-", - "T62262-", - "A62263-", - "A62265-", - "A62266-", - "T62270-", - "T62271-", - "A62272-", - "T62273-", - "A62274-", - "A62277-", - "T62278-", - "A62281-", - "A62284-", - "T62285-", - "T62286-", - "T62287-", - "A62288-", - "T62289-", - "A62290-", - "T62291-", - "T62293-", - "A62294-", - "A62295-", - "A62296-", - "A62297-", - "A62298-", - "T62299-", - "T62300-", - "A62301-", - "A62303-", - "T62304-", - "A62306-", - "A62307-", - "A62308-", - "A62310-", - "A62311-", - "T62312-", - "A62313-", - "T62314-", - "T62316-", - "A62318-", - "A62320-", - "A62321-", - "T62324-", - "T62327-", - "A62328-", - "T62330-", - "T62331-", - "T62333-", - "A62334-", - "T62335-", - "A62336-", - "T62338-", - "A62340-", - "A62342-", - "A62343-", - "T62344-", - "T62345-", - "A62347-", - "A62350-", - "A62351-", - "A62352-", - "A62354-", - "A62355-", - "T62356-", - "T62358-", - "T62359-", - "T62360-", - "T62362-", - "T62363-", - "A62364-", - "A62366-", - "T62367-", - "A62368-", - "T62369-", - "T62370-", - "T62371-", - "T62372-", - "T62373-", - "T62374-", - "T62375-", - "T62377-", - "T62378-", - "A62379-", - "T62380-", - "T62381-", - "A62382-", - "T62384-", - "A62385-", - "A62386-", - "A62390-", - "T62392-", - "T62393-", - "A62394-", - "A62395-", - "T62396-", - "A62397-", - "T62399-", - "A62400-", - "A62403-", - "A62404-", - "T62406-", - "A62409-", - "A62410-", - "A62411-", - "A62412-", - "T62414-", - "A62415-", - "A62417-", - "T62419-", - "T62420-", - "A62422-", - "T62423-", - "T62424-", - "A62425-", - "T62426-", - "T62427-", - "T62429-", - "A62430-", - "T62431-", - "A62432-", - "A62433-", - "T62435-", - "A62436-", - "T62437-", - "A62438-", - "A62440-", - "T62441-", - "A62442-", - "T62446-", - "T62447-", - "A62450-", - "A62451-", - "A62452-", - "T62453-", - "A62454-", - "A62455-", - "T62456-", - "T62458-", - "T62459-", - "T62461-", - "T62463-", - "T62464-", - "T62465-", - "A62467-", - "T62468-", - "A62469-", - "A62470-", - "A62471-", - "A62472-", - "T62474-", - "T62475-", - "A62478-", - "A62480-", - "A62481-", - "A62482-", - "A62483-", - "T62484-", - "T62486-", - "A62487-", - "A62489-", - "A62490-", - "T62491-", - "T62492-", - "T62493-", - "T62494-", - "T62495-", - "T62496-", - "A62497-", - "A62498-", - "A62499-", - "A62500-", - "A62501-", - "T62503-", - "T62504-", - "A62505-", - "T62506-", - "T62508-", - "T62509-", - "T62510-", - "T62511-", - "T62514-", - "A62515-", - "T62516-", - "T62517-", - "A62518-", - "T62520-", - "A62521-", - "A62522-", - "T62523-", - "A62524-", - "T62525-", - "T62528-", - "T62531-", - "T62532-", - "A62533-", - "A62535-", - "T62539-", - "T62540-", - "A62541-", - "T62542-", - "T62543-", - "A62544-", - "T62545-", - "T62546-", - "A62547-", - "A62548-", - "T62549-", - "A62550-", - "T62551-", - "A62553-", - "T62555-", - "A62557-", - "T62558-", - "A62560-", - "A62561-", - "A62562-", - "T62563-", - "A62566-", - "A62568-", - "T62573-", - "T62574-", - "T62576-", - "A62577-", - "A62579-", - "T62580-", - "A62581-", - "T62582-", - "T62586-", - "T62587-", - "T62588-", - "T62589-", - "A62590-", - "T62591-", - "T62592-", - "T62593-", - "A62596-", - "A62598-", - "T62599-", - "T62600-", - "A62601-", - "A62603-", - "T62604-", - "T62607-", - "A62608-", - "A62609-", - "A62610-", - "T62611-", - "A62614-", - "A62615-", - "T62616-", - "A62617-", - "T62619-", - "A62621-", - "A62622-", - "A62623-", - "T62625-", - "A62626-", - "T62627-", - "T62691-", - "T62692-", - "T62695-", - "A62697-", - "A62698-", - "A62699-", - "T62700-", - "A62702-", - "A62703-", - "T62704-", - "A62705-", - "A62706-", - "A62707-", - "A62709-", - "A62710-", - "T62711-", - "T62712-", - "T62713-", - "A62715-", - "A62717-", - "A62718-", - "A62719-", - "T62720-", - "A62723-", - "T62724-", - "T62726-", - "T62727-", - "A62728-", - "A62729-", - "T62730-", - "T62732-", - "A62733-", - "T62734-", - "T62735-", - "A62736-", - "T62738-", - "A62739-", - "A62742-", - "A62743-", - "A62744-", - "T62745-", - "T62746-", - "T62747-", - "T62748-", - "T62749-", - "T62750-", - "A62752-", - "T62756-", - "A62757-", - "T62759-", - "A62762-", - "A62763-", - "T62764-", - "T62765-", - "A62767-", - "A62768-", - "A62770-", - "T62771-", - "T62772-", - "T62774-", - "A62775-", - "A62776-", - "T62777-", - "A62780-", - "T62781-", - "A62783-", - "T62784-", - "T62786-", - "T62787-", - "T62789-", - "A62790-", - "T62793-", - "A62794-", - "T62795-", - "T62796-", - "T62797-", - "A62799-", - "T62800-", - "A62804-", - "T62805-", - "A62806-", - "A62807-", - "A62809-", - "T62810-", - "T62812-", - "T62813-", - "A62814-", - "A62815-", - "T62816-", - "T62817-", - "T62818-", - "A62821-", - "A62822-", - "T62823-", - "A62824-", - "A62827-", - "A62828-", - "T62832-", - "T62833-", - "T62834-", - "T62835-", - "A62836-", - "A62837-", - "T62838-", - "A62839-", - "T62840-", - "T62841-", - "T62842-", - "A62845-", - "T62846-", - "A62848-", - "T62849-", - "A62850-", - "T62851-", - "A62852-", - "T62856-", - "A62857-", - "T62859-", - "T62861-", - "C62862-", - "T62863-", - "T62865-", - "T62866-", - "T62867-", - "A62871-", - "T62873-", - "T62874-", - "A62875-", - "T62876-", - "A62877-", - "T62878-", - "A62879-", - "T62882-", - "T62883-", - "A62884-", - "T62885-", - "T62886-", - "A62889-", - "A62891-", - "A62892-", - "T62893-", - "A62894-", - "A62897-", - "T62899-", - "A62901-", - "T62902-", - "T62903-", - "A62904-", - "T62905-", - "A62906-", - "T62907-", - "A62908-", - "T62910-", - "A62913-", - "A62914-", - "A62915-", - "A62916-", - "A62917-", - "A62918-", - "A62920-", - "A62921-", - "A62922-", - "A62923-", - "T62924-", - "A62925-", - "A62926-", - "T62928-", - "A62929-", - "T62931-", - "A62932-", - "T62933-", - "A62934-", - "A62935-", - "A62936-", - "A62937-", - "T62938-", - "T62940-", - "T62942-", - "A62943-", - "T62944-", - "A62947-", - "A62948-", - "T62949-", - "A62953-", - "A62954-", - "A62955-", - "A62956-", - "A62957-", - "A62960-", - "A62961-", - "A62962-", - "T62963-", - "T62964-", - "A62965-", - "T62966-", - "A62969-", - "T62970-", - "A62971-", - "T62972-", - "A62973-", - "T62976-", - "A62977-", - "T62978-", - "A62979-", - "A62981-", - "A62982-", - "T62983-", - "A62988-", - "A62989-", - "A62991-", - "T62992-", - "T62993-", - "A62995-", - "A62996-", - "T62999-", - "A63000-", - "T63001-", - "T63002-", - "A63003-", - "A63004-", - "T63005-", - "A63006-", - "T63008-", - "T63009-", - "A63010-", - "A63011-", - "T63012-", - "T63013-", - "T63015-", - "T63016-", - "T63017-", - "T63018-", - "T63019-", - "A63021-", - "T63023-", - "T63026-", - "A63027-", - "A63028-", - "A63030-", - "A63031-", - "A63035-", - "T63036-", - "A63037-", - "T63040-", - "T63041-", - "A63042-", - "T63043-", - "T63044-", - "A63046-", - "A63048-", - "T63049-", - "T63050-", - "T63052-", - "A63053-", - "T63054-", - "T63057-", - "T63058-", - "T63059-", - "T63060-", - "A63061-", - "A63062-", - "A63063-", - "T63064-", - "A63065-", - "T63066-", - "T63067-", - "T63069-", - "A63070-", - "T63071-", - "A63072-", - "A63073-", - "T63075-", - "T63076-", - "A63078-", - "A63080-", - "T63082-", - "T63083-", - "A63085-", - "T63086-", - "A63087-", - "A63089-", - "T63090-", - "A63091-", - "T63092-", - "T63093-", - "A63094-", - "A63095-", - "T63096-", - "A63098-", - "A63101-", - "A63102-", - "T63103-", - "T63104-", - "A63106-", - "A63107-", - "A63108-", - "A63109-", - "T63110-", - "T63111-", - "A63112-", - "T63113-", - "T63114-", - "T63115-", - "T63116-", - "T63117-", - "A63118-", - "T63119-", - "A63121-", - "A63124-", - "T63127-", - "T63129-", - "T63131-", - "T63132-", - "T63133-", - "A63135-", - "A63138-", - "T63139-", - "A63141-", - "T63142-", - "T63145-", - "A63148-", - "A63153-", - "T63155-", - "T63156-", - "A63157-", - "A63158-", - "A63161-", - "A63162-", - "A63166-", - "A63167-", - "T63168-", - "A63171-", - "T63173-", - "A63174-", - "A63175-", - "A63176-", - "A63177-", - "T63178-", - "A63179-", - "A63180-", - "A63181-", - "T63182-", - "A63183-", - "T63184-", - "A63186-", - "T63187-", - "T63188-", - "A63189-", - "A63190-", - "T63191-", - "A63192-", - "T63193-", - "A63194-", - "T63195-", - "T63198-", - "T63200-", - "A63201-", - "A63203-", - "T63204-", - "A63205-", - "T63206-", - "T63207-", - "A63208-", - "T63210-", - "A63211-", - "T63212-", - "T63213-", - "T63214-", - "T63215-", - "T63216-", - "A63217-", - "T63218-", - "T63219-", - "A63220-", - "A63221-", - "T63222-", - "T63225-", - "T63226-", - "T63227-", - "A63229-", - "T63230-", - "T63231-", - "A63232-", - "T63233-", - "A63235-", - "T63236-", - "T63238-", - "T63239-", - "T63241-", - "T63244-", - "A63245-", - "A63250-", - "A63251-", - "T63252-", - "A63254-", - "T63255-", - "T63256-", - "A63259-", - "T63260-", - "A63262-", - "T63263-", - "A63265-", - "A63266-", - "A63268-", - "T63270-", - "A63272-", - "T63273-", - "T63274-", - "T63275-", - "A63277-", - "A63279-", - "A63280-", - "A63282-", - "T63283-", - "T63286-", - "A63291-", - "T63293-", - "A63294-", - "T63295-", - "T63296-", - "A63297-", - "A63298-", - "T63299-", - "T63303-", - "T63304-", - "T63305-", - "A63306-", - "T63308-", - "A63309-", - "A63310-", - "A63311-", - "A63313-", - "T63315-", - "A63318-", - "T63319-", - "T63322-", - "T63323-", - "A63326-", - "A63327-", - "T63328-", - "A63329-", - "A63330-", - "T63331-", - "A63332-", - "A63333-", - "A63334-", - "A63335-", - "T63337-", - "T63338-", - "T63340-", - "A63343-", - "A63344-", - "T63346-", - "T63347-", - "A63348-", - "A63349-", - "A63350-", - "A63353-", - "T63354-", - "A63355-", - "T63356-", - "T63357-", - "A63358-", - "T63359-", - "A63362-", - "T63363-", - "T63364-", - "T63367-", - "T63368-", - "T63369-", - "A63370-", - "A63371-", - "A63372-", - "A63374-", - "T63375-", - "A63376-", - "T63377-", - "A63379-", - "T63382-", - "A63384-", - "T63385-", - "T63387-", - "A63388-", - "A63389-", - "A63393-", - "A63395-", - "A63397-", - "A63398-", - "T63399-", - "T63400-", - "T63401-", - "T63402-", - "T63403-", - "T63404-", - "T63407-", - "A63408-", - "T63411-", - "T63412-", - "T63413-", - "T63414-", - "A63415-", - "A63417-", - "A63419-", - "T63421-", - "T63422-", - "T63423-", - "A63425-", - "A63426-", - "T63429-", - "A63430-", - "T63432-", - "T63433-", - "T63435-", - "T63436-", - "T63437-", - "A63438-", - "A63439-", - "A63441-", - "A63442-", - "A63443-", - "T63445-", - "T63446-", - "A63447-", - "T63448-", - "T63449-", - "A63451-", - "T63452-", - "T63455-", - "T63458-", - "T63460-", - "A63461-", - "T63463-", - "A63464-", - "T63465-", - "T63466-", - "T63468-", - "A63469-", - "T63470-", - "T63471-", - "T63472-", - "A63473-", - "A63474-", - "T63475-", - "T63476-", - "T63477-", - "T63478-", - "T63480-", - "A63481-", - "T63483-", - "T63484-", - "A63485-", - "A63486-", - "T63487-", - "T63488-", - "T63489-", - "A63490-", - "T63491-", - "C89166T" - ], - "OPG068": [ - "T503X", - "*568X" - ], - "OPG081": [ - "M1X", - "V2X", - "D3X", - "A4X", - "I5-", - "T6X", - "V7X", - "L8X", - "T9X", - "I11X", - "C12X", - "I13-", - "T14X", - "V15X", - "L16-", - "M17X", - "L18X", - "L19X", - "M20X", - "V21X", - "I22-", - "S23X", - "T25X", - "M27X", - "I28-", - "V29X", - "K30X", - "E31X", - "L32-", - "N33-", - "P34X", - "N35-", - "D36X", - "I37-", - "F38X", - "T39X", - "M40X", - "Q41X", - "N46X", - "R47X", - "T48X", - "V49X", - "T50X", - "I51-", - "F52X", - "K53-", - "Y54-", - "I55-", - "G56X", - "L57X", - "F58-", - "I59X", - "Y60-", - "*80X" - ], - "OPG082": [ - "M1X", - "N2-", - "N3X", - "F4-", - "V5X", - "K6-", - "Q7X", - "V8X", - "A9X", - "S10X", - "K11X", - "S12X", - "L13X", - "K14-", - "P15X", - "T16X", - "K17-", - "K18-", - "L19X", - "S20X", - "L22-", - "D23X", - "E24X", - "V25X", - "I26-", - "S27X", - "L28-", - "N29X", - "E30X", - "C31X", - "I32-", - "I33-", - "S34X", - "F35-", - "N36X", - "L37X", - "D38X", - "N39X", - "F40-", - "Y41-", - "Y42-", - "C43X", - "N44X", - "D45X", - "G46X", - "L47X", - "F48-", - "T49X", - "K50-", - "I52-", - "N53-", - "T54X", - "E56X", - "D57X", - "V58X", - "L59X", - "K60-", - "S61X", - "L62X", - "L63X", - "I64X", - "M65X", - "E66X", - "S67X", - "F68X", - "Y70X", - "E71X", - "K72X", - "M73X", - "I74-", - "I75X", - "K76-", - "G77X", - "L78-", - "I79-", - "K80-", - "I81-", - "L82X", - "I83-", - "S84X", - "R85X", - "A86X", - "Y87-", - "I88-", - "N89-", - "D90X", - "I91-", - "Y92-", - "F93-", - "T94X", - "P95X", - "F96X", - "G97X", - "W98X", - "L99-", - "T100X", - "V102X", - "D103X", - "D104X", - "D105X", - "P106X", - "E107X", - "T108X", - "H109X", - "V110X", - "V111X", - "I112-", - "K113-", - "I114-", - "I115-", - "F116X", - "N117-", - "S118X", - "S119X", - "L120-", - "I121-", - "S122X", - "I123X", - "K124X", - "S125X", - "Q126X", - "V127X", - "I128-", - "E129X", - "Y130-", - "L131-", - "K132-", - "P133X", - "Y134X", - "N135-", - "V136X", - "N137-", - "N138X", - "L139X", - "S140X", - "V141X", - "L142X", - "T143X", - "T144X", - "E145X", - "K146-", - "E147X", - "L148-", - "S149X", - "I150-", - "N151-", - "T152X", - "F153X", - "N154-", - "V155X", - "D157X", - "S158X", - "I159-", - "P160X", - "I161-", - "S162X", - "I163-", - "I164-", - "S165X", - "F166-", - "F167X", - "P168X", - "F169X", - "D170X", - "T171X", - "D172X", - "F173-", - "I174-", - "L175X", - "V176X", - "I177-", - "L178X", - "F179-", - "F180-", - "G181X", - "V182X", - "Y183-", - "N184-", - "D185X", - "S186X", - "Y187-", - "C188X", - "G189X", - "I190-", - "S191X", - "Y192-", - "I193-", - "S194X", - "K196-", - "E197X", - "R198X", - "L199X", - "Y201-", - "I202X", - "I203X", - "E204X", - "I205-", - "L206-", - "K207-", - "L209X", - "V210X", - "L211X", - "E212X", - "I213-", - "N214X", - "M215X", - "L216-", - "S217X", - "D218X", - "E219X", - "I220-", - "G221X", - "R222X", - "T223X", - "S224X", - "S225X", - "I226-", - "R227X", - "I228X", - "F229X", - "N230-", - "S231X", - "T232X", - "S233X", - "V234X", - "K235-", - "K236-", - "F237-", - "P238X", - "T239X", - "N240-", - "T241X", - "L242-", - "T243X", - "S244X", - "I245-", - "C246X", - "E247X", - "I248-", - "V249X", - "Y250-", - "S251X", - "F252-", - "D253X", - "E254X", - "I276-", - "V277X", - "S278X", - "L279X", - "L280X", - "D281X", - "L282-", - "P283X", - "S284X", - "N285-", - "V286X", - "E287X", - "I288-", - "K289-", - "I291-", - "S292X", - "R293X", - "S294X", - "G295X", - "V296X", - "D297X", - "F298X", - "I299X", - "T300X", - "H301X", - "I302-", - "N303-", - "N304-", - "K305X", - "R306X", - "L307X", - "T308X", - "T309X", - "I310-", - "L311-", - "V312X", - "I313-", - "A314X", - "K315-", - "D316X", - "N317X", - "F318-", - "L319-", - "K320-", - "N321-", - "S322X", - "T323X", - "F324-", - "S325X", - "G326X", - "T327X", - "F328-", - "I329X", - "K330-", - "E331X", - "N332X", - "I333-", - "I334-", - "W335X", - "K336X", - "G337X", - "I338X", - "Y339-", - "T340X", - "Y341-", - "R342X", - "I343-", - "I344X", - "K345X", - "S346X", - "S347X", - "F348-", - "P349X", - "V350X", - "P351X", - "T352X", - "I353-", - "K354X", - "S355X", - "V356X", - "T357X", - "N358-", - "K359X", - "K360-", - "K361-", - "I362-", - "C363X", - "K364X", - "K365-", - "H366X", - "C367X", - "F368X", - "V369X", - "N370-", - "S371X", - "Q372X", - "Y373-", - "T374X", - "T375X", - "R376X", - "T377X", - "L378X", - "S379X", - "H380X", - "I381-", - "L382X", - "*383X" - ], - "OPG083": [ - "D409X", - "K410-", - "L411-", - "T412X", - "T413X", - "K414-", - "L415-", - "N416-", - "R417X", - "I418-", - "V419X", - "D420X", - "D421X", - "D422X", - "E423X", - "*424-" - ] - }, - "labels": { - "aa": "OPG068: T503X, *568X; OPG081: M1X, V2X, D3X, A4X, I5-, T6X, V7X, L8X, T9X, I11X, C12X, I13-, T14X, V15X, L16-, M17X, L18X, L19X, M20X, V21X, I22-, S23X, T25X, M27X, I28-, V29X, K30X, E31X, L32-, N33-, P34X, N35-, D36X, I37-, F38X, T39X, M40X, Q41X, N46X, R47X, T48X, V49X, T50X, I51-, F52X, K53-, Y54-, I55-, G56X, L57X, F58-, I59X, Y60-, *80X; OPG082: M1X, N2-, N3X, F4-, V5X, K6-, Q7X, V8X, A9X, S10X, K11X, S12X, L13X, K14-, P15X, T16X, K17-, K18-, L19X, S20X, L22-, D23X, E24X, V25X, I26-, S27X, L28-, N29X, E30X, C31X, I32-, I33-, S34X, F35-, N36X, L37X, D38X, N39X, F40-, Y41-, Y42-, C43X, N44X, D45X, G46X, L47X, F48-, T49X, K50-, I52-, N53-, T54X, E56X, D57X, V58X, L59X, K60-, S61X, L62X, L63X, I64X, M65X, E66X, S67X, F68X, Y70X, E71X, K72X, M73X, I74-, I75X, K76-, G77X, L78-, I79-, K80-, I81-, L82X, I83-, S84X, R85X, A86X, Y87-, I88-, N89-, D90X, I91-, Y92-, F93-, T94X, P95X, F96X, G97X, W98X, L99-, T100X, V102X, D103X, D104X, D105X, P106X, E107X, T108X, H109X, V110X, V111X, I112-, K113-, I114-, I115-, F116X, N117-, S118X, S119X, L120-, I121-, S122X, I123X, K124X, S125X, Q126X, V127X, I128-, E129X, Y130-, L131-, K132-, P133X, Y134X, N135-, V136X, N137-, N138X, L139X, S140X, V141X, L142X, T143X, T144X, E145X, K146-, E147X, L148-, S149X, I150-, N151-, T152X, F153X, N154-, V155X, D157X, S158X, I159-, P160X, I161-, S162X, I163-, I164-, S165X, F166-, F167X, P168X, F169X, D170X, T171X, D172X, F173-, I174-, L175X, V176X, I177-, L178X, F179-, F180-, G181X, V182X, Y183-, N184-, D185X, S186X, Y187-, C188X, G189X, I190-, S191X, Y192-, I193-, S194X, K196-, E197X, R198X, L199X, Y201-, I202X, I203X, E204X, I205-, L206-, K207-, L209X, V210X, L211X, E212X, I213-, N214X, M215X, L216-, S217X, D218X, E219X, I220-, G221X, R222X, T223X, S224X, S225X, I226-, R227X, I228X, F229X, N230-, S231X, T232X, S233X, V234X, K235-, K236-, F237-, P238X, T239X, N240-, T241X, L242-, T243X, S244X, I245-, C246X, E247X, I248-, V249X, Y250-, S251X, F252-, D253X, E254X, I276-, V277X, S278X, L279X, L280X, D281X, L282-, P283X, S284X, N285-, V286X, E287X, I288-, K289-, I291-, S292X, R293X, S294X, G295X, V296X, D297X, F298X, I299X, T300X, H301X, I302-, N303-, N304-, K305X, R306X, L307X, T308X, T309X, I310-, L311-, V312X, I313-, A314X, K315-, D316X, N317X, F318-, L319-, K320-, N321-, S322X, T323X, F324-, S325X, G326X, T327X, F328-, I329X, K330-, E331X, N332X, I333-, I334-, W335X, K336X, G337X, I338X, Y339-, T340X, Y341-, R342X, I343-, I344X, K345X, S346X, S347X, F348-, P349X, V350X, P351X, T352X, I353-, K354X, S355X, V356X, T357X, N358-, K359X, K360-, K361-, I362-, C363X, K364X, K365-, H366X, C367X, F368X, V369X, N370-, S371X, Q372X, Y373-, T374X, T375X, R376X, T377X, L378X, S379X, H380X, I381-, L382X, *383X; OPG083: D409X, K410-, L411-, T412X, T413X, K414-, L415-, N416-, R417X, I418-, V419X, D420X, D421X, D422X, E423X, *424-" - } - }, - "children": [ - { - "name": "02112022_anal", - "node_attrs": { - "div": 63, - "author": { - "author": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K.", - "value": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-11-02" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "02112022_anal" - }, - "strain": { - "value": "OQ672570" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G49679-", - "G62109-", - "G62115-", - "G62117-", - "C62119-", - "C62120-", - "G62130-", - "C62136-", - "G62137-", - "C62141-", - "G62142-", - "G62143-", - "C62146-", - "G62147-", - "G62165-", - "C62166-", - "G62170-", - "G62172-", - "C62180-", - "G62185-", - "G62186-", - "C62193-", - "C62195-", - "C62196-", - "G62199-", - "C62201-", - "C62205-", - "G62208-", - "G62209-", - "C62210-", - "G62211-", - "G62212-", - "G62214-", - "C62215-", - "C62216-", - "G62218-", - "C62225-", - "C62226-", - "C62229-", - "G62234-", - "C62235-", - "C62243-", - "G62245-", - "G62250-", - "C62251-", - "G62253-", - "C62256-", - "G62257-", - "C62258-", - "G62260-", - "G62264-", - "C62267-", - "G62268-", - "G62269-", - "G62275-", - "C62276-", - "C62279-", - "C62280-", - "C62282-", - "C62283-", - "C62292-", - "G62302-", - "C62305-", - "G62309-", - "G62315-", - "G62317-", - "C62319-", - "C62322-", - "G62323-", - "C62325-", - "C62326-", - "G62329-", - "G62332-", - "C62337-", - "G62339-", - "G62341-", - "G62346-", - "C62348-", - "G62349-", - "C62353-", - "G62357-", - "C62361-", - "C62365-", - "C62376-", - "G62383-", - "C62387-", - "C62388-", - "G62389-", - "C62391-", - "G62398-", - "G62401-", - "G62402-", - "C62405-", - "G62407-", - "G62408-", - "C62413-", - "G62416-", - "C62418-", - "G62421-", - "C62428-", - "G62434-", - "G62439-", - "C62443-", - "C62444-", - "C62445-", - "C62448-", - "C62449-", - "G62457-", - "C62460-", - "C62462-", - "G62466-", - "G62473-", - "C62476-", - "C62477-", - "G62479-", - "G62485-", - "G62488-", - "G62502-", - "C62507-", - "G62512-", - "C62513-", - "C62519-", - "C62526-", - "G62527-", - "G62529-", - "G62530-", - "G62534-", - "C62536-", - "G62537-", - "C62538-", - "G62552-", - "G62554-", - "G62556-", - "G62559-", - "C62564-", - "C62565-", - "C62567-", - "C62569-", - "C62570-", - "G62571-", - "C62572-", - "C62575-", - "G62578-", - "C62583-", - "G62584-", - "C62585-", - "C62594-", - "C62595-", - "C62597-", - "G62602-", - "G62605-", - "G62606-", - "C62612-", - "C62613-", - "G62618-", - "G62620-", - "C62624-", - "C62628-", - "C62693-", - "G62694-", - "C62696-", - "G62701-", - "C62708-", - "C62714-", - "C62716-", - "G62721-", - "G62722-", - "G62725-", - "G62731-", - "G62737-", - "G62740-", - "G62741-", - "G62751-", - "C62753-", - "G62754-", - "C62755-", - "G62758-", - "G62760-", - "G62761-", - "G62766-", - "G62769-", - "C62773-", - "G62778-", - "G62779-", - "G62782-", - "G62785-", - "C62788-", - "C62791-", - "C62792-", - "C62798-", - "C62801-", - "C62802-", - "G62803-", - "C62808-", - "G62811-", - "C62819-", - "C62820-", - "C62825-", - "C62826-", - "C62829-", - "G62830-", - "G62831-", - "C62843-", - "G62844-", - "G62847-", - "C62853-", - "G62854-", - "G62855-", - "G62858-", - "C62860-", - "C62864-", - "C62868-", - "G62869-", - "G62870-", - "C62872-", - "G62880-", - "C62881-", - "C62887-", - "C62888-", - "C62890-", - "C62895-", - "G62896-", - "G62898-", - "C62900-", - "C62909-", - "C62911-", - "C62912-", - "C62919-", - "C62927-", - "G62930-", - "C62939-", - "G62941-", - "C62945-", - "G62946-", - "G62950-", - "G62951-", - "G62952-", - "C62958-", - "G62959-", - "C62967-", - "G62968-", - "G62974-", - "G62975-", - "G62980-", - "C62984-", - "C62985-", - "G62986-", - "G62987-", - "C62990-", - "G62994-", - "C62997-", - "G62998-", - "C63007-", - "C63014-", - "C63020-", - "G63022-", - "G63024-", - "G63025-", - "G63029-", - "C63032-", - "C63033-", - "G63034-", - "G63038-", - "G63039-", - "G63045-", - "C63047-", - "G63051-", - "G63055-", - "G63056-", - "C63068-", - "C63074-", - "G63077-", - "G63079-", - "C63081-", - "G63084-", - "G63088-", - "G63097-", - "C63099-", - "G63100-", - "G63105-", - "C63120-", - "C63122-", - "C63123-", - "C63125-", - "G63126-", - "G63128-", - "G63130-", - "C63134-", - "G63136-", - "G63137-", - "C63140-", - "C63143-", - "G63144-", - "C63146-", - "G63147-", - "C63149-", - "G63150-", - "C63151-", - "C63152-", - "G63154-", - "C63159-", - "C63160-", - "C63163-", - "C63164-", - "G63165-", - "G63169-", - "G63170-", - "G63172-", - "C63185-", - "G63196-", - "C63197-", - "C63199-", - "G63202-", - "G63209-", - "C63223-", - "C63224-", - "G63228-", - "C63234-", - "C63237-", - "C63240-", - "C63242-", - "G63243-", - "C63246-", - "G63247-", - "C63248-", - "G63249-", - "G63253-", - "C63257-", - "C63258-", - "G63261-", - "C63264-", - "G63267-", - "G63269-", - "G63271-", - "G63276-", - "G63278-", - "C63281-", - "C63284-", - "C63285-", - "C63287-", - "C63288-", - "G63289-", - "G63290-", - "G63292-", - "G63300-", - "G63301-", - "G63302-", - "G63307-", - "C63312-", - "G63314-", - "C63316-", - "C63317-", - "C63320-", - "G63321-", - "G63324-", - "C63325-", - "G63336-", - "G63339-", - "C63341-", - "C63342-", - "G63345-", - "G63351-", - "G63352-", - "G63360-", - "C63361-", - "C63365-", - "G63366-", - "G63373-", - "C63378-", - "C63380-", - "C63381-", - "C63383-", - "C63386-", - "C63390-", - "G63391-", - "G63392-", - "G63394-", - "C63396-", - "G63405-", - "G63406-", - "G63409-", - "G63410-", - "G63416-", - "G63418-", - "C63420-", - "G63424-", - "G63427-", - "C63428-", - "C63431-", - "G63434-", - "C63440-", - "G63444-", - "C63450-", - "C63453-", - "G63454-", - "C63456-", - "G63457-", - "C63459-", - "C63462-", - "C63467-", - "G63479-", - "G63482-", - "C63492-" - ], - "OPG068": [ - "E493X" - ], - "OPG081": [ - "X1-", - "X2-", - "X3-", - "X4-", - "X6-", - "X7-", - "X8-", - "X9-", - "A10-", - "X11-", - "X12-", - "X14-", - "X15-", - "X17-", - "X18-", - "X19-", - "X20-", - "X21-", - "X23-", - "G24-", - "X25-", - "A26-", - "X27-", - "X29-", - "X30-", - "X31-", - "X34-", - "X36-", - "X38-", - "X39-", - "X40-", - "X47-", - "X48-", - "X49-", - "X50-", - "X52-", - "X56-", - "X57-", - "X59-" - ], - "OPG082": [ - "X1-", - "X3-", - "X5-", - "X7-", - "X8-", - "X9-", - "X10-", - "X11-", - "X12-", - "X13-", - "X15-", - "X16-", - "X19-", - "X20-", - "P21-", - "X23-", - "X24-", - "X25-", - "X27-", - "X29-", - "X30-", - "X31-", - "X34-", - "X36-", - "X37-", - "X38-", - "X39-", - "X43-", - "X44-", - "X45-", - "X46-", - "X47-", - "X49-", - "P51-", - "X54-", - "P55-", - "X56-", - "X57-", - "X58-", - "X59-", - "X61-", - "X62-", - "X63-", - "X64-", - "X65-", - "X66-", - "X67-", - "X68-", - "A69-", - "X70-", - "X71-", - "X72-", - "X73-", - "X75-", - "X77-", - "X82-", - "X84-", - "X85-", - "X86-", - "X90-", - "X94-", - "X95-", - "X96-", - "X97-", - "X98-", - "X100-", - "G101-", - "X102-", - "X103-", - "X104-", - "X105-", - "X106-", - "X107-", - "X108-", - "X109-", - "X110-", - "X111-", - "X116-", - "X118-", - "X119-", - "X122-", - "X123-", - "X124-", - "X125-", - "X126-", - "X127-", - "X129-", - "X133-", - "X134-", - "X136-", - "X138-", - "X139-", - "X140-", - "X141-", - "X142-", - "X143-", - "X144-", - "X145-", - "X147-", - "X149-", - "X152-", - "X153-", - "X155-", - "P156-", - "X157-", - "X158-", - "X160-", - "X162-", - "X165-", - "X167-", - "X168-", - "X169-", - "X170-", - "X171-", - "X172-", - "X175-", - "X176-", - "X178-", - "X181-", - "X182-", - "X185-", - "X186-", - "X188-", - "X189-", - "X191-", - "X194-", - "P195-", - "X197-", - "X198-", - "X199-", - "P200-", - "X202-", - "X203-", - "X204-", - "P208-", - "X209-", - "X210-", - "X211-", - "X212-", - "X214-", - "X215-", - "X217-", - "X218-", - "X219-", - "X221-", - "X222-", - "X223-", - "X224-", - "X225-", - "X227-", - "X228-", - "X229-", - "X231-", - "X232-", - "X233-", - "X234-", - "X238-", - "X239-", - "X241-", - "X243-", - "X244-", - "X246-", - "X247-", - "X249-", - "X251-", - "X253-", - "X254-", - "K275X", - "X277-", - "X278-", - "X279-", - "X280-", - "X281-", - "X283-", - "X284-", - "X286-", - "X287-", - "A290-", - "X292-", - "X293-", - "X294-", - "X295-", - "X296-", - "X297-", - "X298-", - "X299-", - "X300-", - "X301-", - "X305-", - "X306-", - "X307-", - "X308-", - "X309-", - "X312-", - "X314-", - "X316-", - "X317-", - "X322-", - "X323-", - "X325-", - "X326-", - "X327-", - "X329-", - "X331-", - "X332-", - "X335-", - "X336-", - "X337-", - "X338-", - "X340-", - "X342-", - "X344-", - "X345-", - "X346-", - "X347-", - "X349-", - "X350-", - "X351-", - "X352-", - "X354-", - "X355-", - "X356-", - "X357-", - "X359-", - "X363-", - "X364-", - "X366-", - "X367-", - "X368-", - "X369-", - "X371-", - "X372-", - "X374-", - "X375-", - "X376-", - "X377-", - "X378-", - "X379-", - "X380-", - "X382-", - "X383-" - ], - "OPG083": [ - "X409-", - "X412-", - "X413-", - "X417-", - "X419-", - "X420-", - "X421-", - "X422-", - "X423-" - ] - }, - "labels": { - "aa": "OPG068: E493X; OPG081: X1-, X2-, X3-, X4-, X6-, X7-, X8-, X9-, A10-, X11-, X12-, X14-, X15-, X17-, X18-, X19-, X20-, X21-, X23-, G24-, X25-, A26-, X27-, X29-, X30-, X31-, X34-, X36-, X38-, X39-, X40-, X47-, X48-, X49-, X50-, X52-, X56-, X57-, X59-; OPG082: X1-, X3-, X5-, X7-, X8-, X9-, X10-, X11-, X12-, X13-, X15-, X16-, X19-, X20-, P21-, X23-, X24-, X25-, X27-, X29-, X30-, X31-, X34-, X36-, X37-, X38-, X39-, X43-, X44-, X45-, X46-, X47-, X49-, P51-, X54-, P55-, X56-, X57-, X58-, X59-, X61-, X62-, X63-, X64-, X65-, X66-, X67-, X68-, A69-, X70-, X71-, X72-, X73-, X75-, X77-, X82-, X84-, X85-, X86-, X90-, X94-, X95-, X96-, X97-, X98-, X100-, G101-, X102-, X103-, X104-, X105-, X106-, X107-, X108-, X109-, X110-, X111-, X116-, X118-, X119-, X122-, X123-, X124-, X125-, X126-, X127-, X129-, X133-, X134-, X136-, X138-, X139-, X140-, X141-, X142-, X143-, X144-, X145-, X147-, X149-, X152-, X153-, X155-, P156-, X157-, X158-, X160-, X162-, X165-, X167-, X168-, X169-, X170-, X171-, X172-, X175-, X176-, X178-, X181-, X182-, X185-, X186-, X188-, X189-, X191-, X194-, P195-, X197-, X198-, X199-, P200-, X202-, X203-, X204-, P208-, X209-, X210-, X211-, X212-, X214-, X215-, X217-, X218-, X219-, X221-, X222-, X223-, X224-, X225-, X227-, X228-, X229-, X231-, X232-, X233-, X234-, X238-, X239-, X241-, X243-, X244-, X246-, X247-, X249-, X251-, X253-, X254-, K275X, X277-, X278-, X279-, X280-, X281-, X283-, X284-, X286-, X287-, A290-, X292-, X293-, X294-, X295-, X296-, X297-, X298-, X299-, X300-, X301-, X305-, X306-, X307-, X308-, X309-, X312-, X314-, X316-, X317-, X322-, X323-, X325-, X326-, X327-, X329-, X331-, X332-, X335-, X336-, X337-, X338-, X340-, X342-, X344-, X345-, X346-, X347-, X349-, X350-, X351-, X352-, X354-, X355-, X356-, X357-, X359-, X363-, X364-, X366-, X367-, X368-, X369-, X371-, X372-, X374-, X375-, X376-, X377-, X378-, X379-, X380-, X382-, X383-; OPG083: X409-, X412-, X413-, X417-, X419-, X420-, X421-, X422-, X423-" - } - } - }, - { - "name": "02022023_anal", - "node_attrs": { - "div": 66, - "author": { - "author": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K.", - "value": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2023-02-02" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "02022023_anal" - }, - "strain": { - "value": "OQ672574" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-49707A", - "-62106A", - "-62107T", - "-62108A", - "-62110A", - "-62111T", - "-62112A", - "-62113A", - "-62114A", - "-62116A", - "-62118T", - "-62121T", - "-62122A", - "-62123T", - "-62124A", - "-62125T", - "-62126A", - "-62127T", - "-62128T", - "-62129T", - "-62131A", - "-62132A", - "-62133A", - "-62134A", - "-62135T", - "-62138T", - "-62139T", - "-62140A", - "-62144T", - "-62145T", - "-62148A", - "-62164T", - "-62167A", - "-62168T", - "-62169T", - "-62171T", - "-62173A", - "-62174A", - "-62175T", - "-62176A", - "-62177T", - "-62178A", - "-62179T", - "-62181A", - "-62182T", - "-62183T", - "-62184A", - "-62187A", - "-62188T", - "-62189T", - "-62190T", - "-62191A", - "-62192A", - "-62194T", - "-62197T", - "-62198T", - "-62200A", - "-62202T", - "-62203A", - "-62204T", - "-62206A", - "-62207T", - "-62213T", - "-62217A", - "-62219A", - "-62220A", - "-62221A", - "-62222T", - "-62223T", - "-62224A", - "-62227A", - "-62228T", - "-62230A", - "-62231A", - "-62232A", - "-62233A", - "-62236A", - "-62237T", - "-62238T", - "-62239A", - "-62240A", - "-62241T", - "-62242A", - "-62244A", - "-62246T", - "-62247T", - "-62248A", - "-62249T", - "-62252A", - "-62254A", - "-62255T", - "-62259A", - "-62261T", - "-62262T", - "-62263A", - "-62265A", - "-62266A", - "-62270T", - "-62271T", - "-62272A", - "-62273T", - "-62274A", - "-62277A", - "-62278T", - "-62281A", - "-62284A", - "-62285T", - "-62286T", - "-62287T", - "-62288A", - "-62289T", - "-62290A", - "-62291T", - "-62293T", - "-62294A", - "-62295A", - "-62296A", - "-62297A", - "-62298A", - "-62299T", - "-62300T", - "-62301A", - "-62303A", - "-62304T", - "-62306A", - "-62307A", - "-62308A", - "-62310A", - "-62311A", - "-62312T", - "-62313A", - "-62314T", - "-62316T", - "-62318A", - "-62320A", - "-62321A", - "-62324T", - "-62327T", - "-62328A", - "-62330T", - "-62331T", - "-62333T", - "-62334A", - "-62335T", - "-62336A", - "-62338T", - "-62340A", - "-62342A", - "-62343A", - "-62344T", - "-62345T", - "-62347A", - "-62350A", - "-62351A", - "-62352A", - "-62354A", - "-62355A", - "-62356T", - "-62358T", - "-62359T", - "-62360T", - "-62362T", - "-62363T", - "-62364A", - "-62366A", - "-62367T", - "-62368A", - "-62369T", - "-62370T", - "-62371T", - "-62372T", - "-62373T", - "-62374T", - "-62375T", - "-62377T", - "-62378T", - "-62379A", - "-62380T", - "-62381T", - "-62382A", - "-62384T", - "-62385A", - "-62386A", - "-62390A", - "-62392T", - "-62393T", - "-62394A", - "-62395A", - "-62396T", - "-62397A", - "-62399T", - "-62400A", - "-62403A", - "-62404A", - "-62406T", - "-62409A", - "-62410A", - "-62411A", - "-62412A", - "-62414T", - "-62415A", - "-62417A", - "-62419T", - "-62420T", - "-62422A", - "-62423T", - "-62424T", - "-62425A", - "-62426T", - "-62427T", - "-62429T", - "-62430A", - "-62431T", - "-62432A", - "-62433A", - "-62435T", - "-62436A", - "-62437T", - "-62438A", - "-62440A", - "-62441T", - "-62442A", - "-62446T", - "-62447T", - "-62450A", - "-62451A", - "-62452A", - "-62453T", - "-62454A", - "-62455A", - "-62456T", - "-62458T", - "-62459T", - "-62461T", - "-62463T", - "-62464T", - "-62465T", - "-62467A", - "-62468T", - "-62469A", - "-62470A", - "-62471A", - "-62472A", - "-62474T", - "-62475T", - "-62478A", - "-62480A", - "-62481A", - "-62482A", - "-62483A", - "-62484T", - "-62486T", - "-62487A", - "-62489A", - "-62490A", - "-62491T", - "-62492T", - "-62493T", - "-62494T", - "-62495T", - "-62496T", - "-62497A", - "-62498A", - "-62499A", - "-62500A", - "-62501A", - "-62503T", - "-62504T", - "-62505A", - "-62506T", - "-62508T", - "-62509T", - "-62510T", - "-62511T", - "-62514T", - "-62515A", - "-62516T", - "-62517T", - "-62518A", - "-62520T", - "-62521A", - "-62522A", - "-62523T", - "-62524A", - "-62525T", - "-62528T", - "-62531T", - "-62532T", - "-62533A", - "-62535A", - "-62539T", - "-62540T", - "-62541A", - "-62542T", - "-62543T", - "-62544A", - "-62545T", - "-62546T", - "-62547A", - "-62548A", - "-62549T", - "-62550A", - "-62551T", - "-62553A", - "-62555T", - "-62557A", - "-62558T", - "-62560A", - "-62561A", - "-62562A", - "-62563T", - "-62566A", - "-62568A", - "-62573T", - "-62574T", - "-62576T", - "-62577A", - "-62579A", - "-62580T", - "-62581A", - "-62582T", - "-62586T", - "-62587T", - "-62588T", - "-62589T", - "-62590A", - "-62591T", - "-62592T", - "-62593T", - "-62596A", - "-62598A", - "-62599T", - "-62600T", - "-62601A", - "-62603A", - "-62604T", - "-62607T", - "-62608A", - "-62609A", - "-62610A", - "-62611T", - "-62614A", - "-62615A", - "-62616T", - "-62617A", - "-62619T", - "-62621A", - "-62622A", - "-62623A", - "-62625T", - "-62626A", - "-62627T", - "-62691T", - "-62692T", - "-62695T", - "-62697A", - "-62698A", - "-62699A", - "-62700T", - "-62702A", - "-62703A", - "-62704T", - "-62705A", - "-62706A", - "-62707A", - "-62709A", - "-62710A", - "-62711T", - "-62712T", - "-62713T", - "-62715A", - "-62717A", - "-62718A", - "-62719A", - "-62720T", - "-62723A", - "-62724T", - "-62726T", - "-62727T", - "-62728A", - "-62729A", - "-62730T", - "-62732T", - "-62733A", - "-62734T", - "-62735T", - "-62736A", - "-62738T", - "-62739A", - "-62742A", - "-62743A", - "-62744A", - "-62745T", - "-62746T", - "-62747T", - "-62748T", - "-62749T", - "-62750T", - "-62752A", - "-62756T", - "-62757A", - "-62759T", - "-62762A", - "-62763A", - "-62764T", - "-62765T", - "-62767A", - "-62768A", - "-62770A", - "-62771T", - "-62772T", - "-62774T", - "-62775A", - "-62776A", - "-62777T", - "-62780A", - "-62781T", - "-62783A", - "-62784T", - "-62786T", - "-62787T", - "-62789T", - "-62790A", - "-62793T", - "-62794A", - "-62795T", - "-62796T", - "-62797T", - "-62799A", - "-62800T", - "-62804A", - "-62805T", - "-62806A", - "-62807A", - "-62809A", - "-62810T", - "-62812T", - "-62813T", - "-62814A", - "-62815A", - "-62816T", - "-62817T", - "-62818T", - "-62821A", - "-62822A", - "-62823T", - "-62824A", - "-62827A", - "-62828A", - "-62832T", - "-62833T", - "-62834T", - "-62835T", - "-62836A", - "-62837A", - "-62838T", - "-62839A", - "-62840T", - "-62841T", - "-62842T", - "-62845A", - "-62846T", - "-62848A", - "-62849T", - "-62850A", - "-62851T", - "-62852A", - "-62856T", - "-62857A", - "-62859T", - "-62863T", - "-62865T", - "-62866T", - "-62867T", - "-62871A", - "-62873T", - "-62874T", - "-62875A", - "-62876T", - "-62877A", - "-62878T", - "-62879A", - "-62882T", - "-62883T", - "-62884A", - "-62885T", - "-62886T", - "-62889A", - "-62891A", - "-62892A", - "-62893T", - "-62894A", - "-62897A", - "-62899T", - "-62901A", - "-62902T", - "-62903T", - "-62904A", - "-62905T", - "-62906A", - "-62907T", - "-62908A", - "-62910T", - "-62913A", - "-62914A", - "-62915A", - "-62916A", - "-62917A", - "-62918A", - "-62920A", - "-62921A", - "-62922A", - "-62923A", - "-62924T", - "-62925A", - "-62926A", - "-62928T", - "-62929A", - "-62931T", - "-62932A", - "-62933T", - "-62934A", - "-62935A", - "-62936A", - "-62937A", - "-62938T", - "-62940T", - "-62942T", - "-62943A", - "-62944T", - "-62947A", - "-62948A", - "-62949T", - "-62953A", - "-62954A", - "-62955A", - "-62956A", - "-62957A", - "-62960A", - "-62961A", - "-62962A", - "-62963T", - "-62964T", - "-62965A", - "-62966T", - "-62969A", - "-62970T", - "-62971A", - "-62972T", - "-62973A", - "-62976T", - "-62977A", - "-62978T", - "-62979A", - "-62981A", - "-62982A", - "-62983T", - "-62988A", - "-62989A", - "-62991A", - "-62992T", - "-62993T", - "-62995A", - "-62996A", - "-62999T", - "-63000A", - "-63001T", - "-63002T", - "-63003A", - "-63004A", - "-63005T", - "-63006A", - "-63008T", - "-63009T", - "-63010A", - "-63011A", - "-63012T", - "-63013T", - "-63015T", - "-63016T", - "-63017T", - "-63018T", - "-63019T", - "-63021A", - "-63023T", - "-63026T", - "-63027A", - "-63028A", - "-63030A", - "-63031A", - "-63035A", - "-63036T", - "-63037A", - "-63040T", - "-63041T", - "-63042A", - "-63043T", - "-63044T", - "-63046A", - "-63048A", - "-63049T", - "-63050T", - "-63052T", - "-63053A", - "-63054T", - "-63057T", - "-63058T", - "-63059T", - "-63060T", - "-63061A", - "-63062A", - "-63063A", - "-63064T", - "-63065A", - "-63066T", - "-63067T", - "-63069T", - "-63070A", - "-63071T", - "-63072A", - "-63073A", - "-63075T", - "-63076T", - "-63078A", - "-63080A", - "-63082T", - "-63083T", - "-63085A", - "-63086T", - "-63087A", - "-63089A", - "-63090T", - "-63091A", - "-63092T", - "-63093T", - "-63094A", - "-63095A", - "-63096T", - "-63098A", - "-63101A", - "-63102A", - "-63103T", - "-63104T", - "-63106A", - "-63107A", - "-63108A", - "-63109A", - "-63110T", - "-63111T", - "-63112A", - "-63113T", - "-63114T", - "-63115T", - "-63116T", - "-63117T", - "-63118A", - "-63119T", - "-63121A", - "-63124A", - "-63127T", - "-63129T", - "-63131T", - "-63132T", - "-63133T", - "-63135A", - "-63138A", - "-63139T", - "-63141A", - "-63142T", - "-63145T", - "-63148A", - "-63153A", - "-63155T", - "-63156T", - "-63157A", - "-63158A", - "-63161A", - "-63162A", - "-63166A", - "-63167A", - "-63168T", - "-63171A", - "-63173T", - "-63174A", - "-63175A", - "-63176A", - "-63177A", - "-63178T", - "-63179A", - "-63180A", - "-63181A", - "-63182T", - "-63183A", - "-63184T", - "-63186A", - "-63187T", - "-63188T", - "-63189A", - "-63190A", - "-63191T", - "-63192A", - "-63193T", - "-63194A", - "-63195T", - "-63198T", - "-63200T", - "-63201A", - "-63203A", - "-63204T", - "-63205A", - "-63206T", - "-63207T", - "-63208A", - "-63210T", - "-63211A", - "-63212T", - "-63213T", - "-63214T", - "-63215T", - "-63216T", - "-63217A", - "-63218T", - "-63219T", - "-63220A", - "-63221A", - "-63222T", - "-63225T", - "-63226T", - "-63227T", - "-63229A", - "-63230T", - "-63231T", - "-63232A", - "-63233T", - "-63235A", - "-63236T", - "-63238T", - "-63239T", - "-63241T", - "-63244T", - "-63245A", - "-63250A", - "-63251A", - "-63252T", - "-63254A", - "-63255T", - "-63256T", - "-63259A", - "-63260T", - "-63262A", - "-63263T", - "-63265A", - "-63266A", - "-63268A", - "-63270T", - "-63272A", - "-63273T", - "-63274T", - "-63275T", - "-63277A", - "-63279A", - "-63280A", - "-63282A", - "-63283T", - "-63286T", - "-63291A", - "-63293T", - "-63294A", - "-63295T", - "-63296T", - "-63297A", - "-63298A", - "-63299T", - "-63303T", - "-63304T", - "-63305T", - "-63306A", - "-63308T", - "-63309A", - "-63310A", - "-63311A", - "-63313A", - "-63315T", - "-63318A", - "-63319T", - "-63322T", - "-63323T", - "-63326A", - "-63327A", - "-63328T", - "-63329A", - "-63330A", - "-63331T", - "-63332A", - "-63333A", - "-63334A", - "-63335A", - "-63337T", - "-63338T", - "-63340T", - "-63343A", - "-63344A", - "-63346T", - "-63347T", - "-63348A", - "-63349A", - "-63350A", - "-63353A", - "-63354T", - "-63355A", - "-63356T", - "-63357T", - "-63358A", - "-63359T", - "-63362A", - "-63363T", - "-63364T", - "-63367T", - "-63368T", - "-63369T", - "-63370A", - "-63371A", - "-63372A", - "-63374A", - "-63375T", - "-63376A", - "-63377T", - "-63379A", - "-63382T", - "-63384A", - "-63385T", - "-63387T", - "-63388A", - "-63389A", - "-63393A", - "-63395A", - "-63397A", - "-63398A", - "-63399T", - "-63400T", - "-63401T", - "-63402T", - "-63403T", - "-63404T", - "-63407T", - "-63408A", - "-63411T", - "-63412T", - "-63413T", - "-63414T", - "-63415A", - "-63417A", - "-63419A", - "-63421T", - "-63422T", - "-63423T", - "-63425A", - "-63426A", - "-63429T", - "-63430A", - "-63432T", - "-63433T", - "-63435T", - "-63436T", - "-63437T", - "-63438A", - "-63439A", - "-63441A", - "-63442A", - "-63443A", - "-63445T", - "-63446T", - "-63447A", - "-63448T", - "-63449T", - "-63451A", - "-63452T", - "-63455T", - "-63458T", - "-63460T", - "-63461A", - "-63463T", - "-63464A", - "-63465T", - "-63466T", - "-63468T", - "-63469A", - "-63470T", - "-63471T", - "-63472T", - "-63473A", - "-63474A", - "-63475T", - "-63476T", - "-63477T", - "-63478T", - "-63480T", - "-63481A", - "-63483T", - "-63484T", - "-63485A", - "-63486A", - "-63487T", - "-63488T", - "-63489T", - "-63490A", - "-63491T", - "C151552T", - "C167451T", - "A178687-", - "T178688-", - "A178689-", - "A178690-", - "A178691-", - "T178692-", - "C178693-", - "C178694-", - "A178695-", - "G178696-", - "G178697-", - "C178698-", - "T178699-", - "C178700-", - "T178701-", - "C178702-", - "G178703-", - "C178704-", - "G187391A" - ], - "OPG068": [ - "X503T", - "X568*" - ], - "OPG081": [ - "X1M", - "X2V", - "X3D", - "X4A", - "-5I", - "X6T", - "X7V", - "X8L", - "X9T", - "X11I", - "X12C", - "-13I", - "X14T", - "X15V", - "-16L", - "X17M", - "X18L", - "X19L", - "X20M", - "X21V", - "-22I", - "X23S", - "X25T", - "X27M", - "-28I", - "X29V", - "X30K", - "X31E", - "-32L", - "-33N", - "X34P", - "-35N", - "X36D", - "-37I", - "X38F", - "X39T", - "X40M", - "X41Q", - "X46N", - "X47R", - "X48T", - "X49V", - "X50T", - "-51I", - "X52F", - "-53K", - "-54Y", - "-55I", - "X56G", - "X57L", - "-58F", - "X59I", - "-60Y", - "X80*" - ], - "OPG082": [ - "X1M", - "-2N", - "X3N", - "-4F", - "X5V", - "-6K", - "X7Q", - "X8V", - "X9A", - "X10S", - "X11K", - "X12S", - "X13L", - "-14K", - "X15P", - "X16T", - "-17K", - "-18K", - "X19L", - "X20S", - "-22L", - "X23D", - "X24E", - "X25V", - "-26I", - "X27S", - "-28L", - "X29N", - "X30E", - "X31C", - "-32I", - "-33I", - "X34S", - "-35F", - "X36N", - "X37L", - "X38D", - "X39N", - "-40F", - "-41Y", - "-42Y", - "X43C", - "X44N", - "X45D", - "X46G", - "X47L", - "-48F", - "X49T", - "-50K", - "-52I", - "-53N", - "X54T", - "X56E", - "X57D", - "X58V", - "X59L", - "-60K", - "X61S", - "X62L", - "X63L", - "X64I", - "X65M", - "X66E", - "X67S", - "X68F", - "X70Y", - "X71E", - "X72K", - "X73M", - "-74I", - "X75I", - "-76K", - "X77G", - "-78L", - "-79I", - "-80K", - "-81I", - "X82L", - "-83I", - "X84S", - "X85R", - "X86A", - "-87Y", - "-88I", - "-89N", - "X90D", - "-91I", - "-92Y", - "-93F", - "X94T", - "X95P", - "X96F", - "X97G", - "X98W", - "-99L", - "X100T", - "X102V", - "X103D", - "X104D", - "X105D", - "X106P", - "X107E", - "X108T", - "X109H", - "X110V", - "X111V", - "-112I", - "-113K", - "-114I", - "-115I", - "X116F", - "-117N", - "X118S", - "X119S", - "-120L", - "-121I", - "X122S", - "X123I", - "X124K", - "X125S", - "X126Q", - "X127V", - "-128I", - "X129E", - "-130Y", - "-131L", - "-132K", - "X133P", - "X134Y", - "-135N", - "X136V", - "-137N", - "X138N", - "X139L", - "X140S", - "X141V", - "X142L", - "X143T", - "X144T", - "X145E", - "-146K", - "X147E", - "-148L", - "X149S", - "-150I", - "-151N", - "X152T", - "X153F", - "-154N", - "X155V", - "X157D", - "X158S", - "-159I", - "X160P", - "-161I", - "X162S", - "-163I", - "-164I", - "X165S", - "-166F", - "X167F", - "X168P", - "X169F", - "X170D", - "X171T", - "X172D", - "-173F", - "-174I", - "X175L", - "X176V", - "-177I", - "X178L", - "-179F", - "-180F", - "X181G", - "X182V", - "-183Y", - "-184N", - "X185D", - "X186S", - "-187Y", - "X188C", - "X189G", - "-190I", - "X191S", - "-192Y", - "-193I", - "X194S", - "-196K", - "X199L", - "-201Y", - "X202I", - "X203I", - "X204E", - "-205I", - "-206L", - "-207K", - "X209L", - "X210V", - "X211L", - "X212E", - "-213I", - "X214N", - "X215M", - "-216L", - "X217S", - "X218D", - "X219E", - "-220I", - "X221G", - "X222R", - "X223T", - "X224S", - "X225S", - "-226I", - "X227R", - "X228I", - "X229F", - "-230N", - "X231S", - "X232T", - "X233S", - "X234V", - "-235K", - "-236K", - "-237F", - "X238P", - "X239T", - "-240N", - "X241T", - "-242L", - "X243T", - "X244S", - "-245I", - "X246C", - "X247E", - "-248I", - "X249V", - "-250Y", - "X251S", - "-252F", - "X253D", - "X254E", - "-276I", - "X277V", - "X278S", - "X279L", - "X280L", - "X281D", - "-282L", - "X283P", - "X284S", - "-285N", - "X286V", - "X287E", - "-288I", - "-289K", - "-291I", - "X292S", - "X293R", - "X294S", - "X295G", - "X296V", - "X297D", - "X298F", - "X299I", - "X300T", - "X301H", - "-302I", - "-303N", - "-304N", - "X305K", - "X306R", - "X307L", - "X308T", - "X309T", - "-310I", - "-311L", - "X312V", - "-313I", - "X314A", - "-315K", - "X316D", - "X317N", - "-318F", - "-319L", - "-320K", - "-321N", - "X322S", - "X323T", - "-324F", - "X325S", - "X326G", - "X327T", - "-328F", - "X329I", - "-330K", - "X331E", - "X332N", - "-333I", - "-334I", - "X335W", - "X336K", - "X337G", - "X338I", - "-339Y", - "X340T", - "-341Y", - "X342R", - "-343I", - "X344I", - "X345K", - "X346S", - "X347S", - "-348F", - "X349P", - "X350V", - "X351P", - "X352T", - "-353I", - "X354K", - "X355S", - "X356V", - "X357T", - "-358N", - "X359K", - "-360K", - "-361K", - "-362I", - "X363C", - "X364K", - "-365K", - "X366H", - "X367C", - "X368F", - "X369V", - "-370N", - "X371S", - "X372Q", - "-373Y", - "X374T", - "X375T", - "X376R", - "X377T", - "X378L", - "X379S", - "X380H", - "-381I", - "X382L" - ], - "OPG083": [ - "X409D", - "-410K", - "-411L", - "X412T", - "X413T", - "-414K", - "-415L", - "-416N", - "X417R", - "-418I", - "X419V", - "X420D", - "X421D", - "X422D", - "X423E", - "-424*" - ], - "OPG178": [ - "S15F" - ] - }, - "labels": { - "aa": "OPG068: X503T, X568*; OPG081: X1M, X2V, X3D, X4A, -5I, X6T, X7V, X8L, X9T, X11I, X12C, -13I, X14T, X15V, -16L, X17M, X18L, X19L, X20M, X21V, -22I, X23S, X25T, X27M, -28I, X29V, X30K, X31E, -32L, -33N, X34P, -35N, X36D, -37I, X38F, X39T, X40M, X41Q, X46N, X47R, X48T, X49V, X50T, -51I, X52F, -53K, -54Y, -55I, X56G, X57L, -58F, X59I, -60Y, X80*; OPG082: X1M, -2N, X3N, -4F, X5V, -6K, X7Q, X8V, X9A, X10S, X11K, X12S, X13L, -14K, X15P, X16T, -17K, -18K, X19L, X20S, -22L, X23D, X24E, X25V, -26I, X27S, -28L, X29N, X30E, X31C, -32I, -33I, X34S, -35F, X36N, X37L, X38D, X39N, -40F, -41Y, -42Y, X43C, X44N, X45D, X46G, X47L, -48F, X49T, -50K, -52I, -53N, X54T, X56E, X57D, X58V, X59L, -60K, X61S, X62L, X63L, X64I, X65M, X66E, X67S, X68F, X70Y, X71E, X72K, X73M, -74I, X75I, -76K, X77G, -78L, -79I, -80K, -81I, X82L, -83I, X84S, X85R, X86A, -87Y, -88I, -89N, X90D, -91I, -92Y, -93F, X94T, X95P, X96F, X97G, X98W, -99L, X100T, X102V, X103D, X104D, X105D, X106P, X107E, X108T, X109H, X110V, X111V, -112I, -113K, -114I, -115I, X116F, -117N, X118S, X119S, -120L, -121I, X122S, X123I, X124K, X125S, X126Q, X127V, -128I, X129E, -130Y, -131L, -132K, X133P, X134Y, -135N, X136V, -137N, X138N, X139L, X140S, X141V, X142L, X143T, X144T, X145E, -146K, X147E, -148L, X149S, -150I, -151N, X152T, X153F, -154N, X155V, X157D, X158S, -159I, X160P, -161I, X162S, -163I, -164I, X165S, -166F, X167F, X168P, X169F, X170D, X171T, X172D, -173F, -174I, X175L, X176V, -177I, X178L, -179F, -180F, X181G, X182V, -183Y, -184N, X185D, X186S, -187Y, X188C, X189G, -190I, X191S, -192Y, -193I, X194S, -196K, X199L, -201Y, X202I, X203I, X204E, -205I, -206L, -207K, X209L, X210V, X211L, X212E, -213I, X214N, X215M, -216L, X217S, X218D, X219E, -220I, X221G, X222R, X223T, X224S, X225S, -226I, X227R, X228I, X229F, -230N, X231S, X232T, X233S, X234V, -235K, -236K, -237F, X238P, X239T, -240N, X241T, -242L, X243T, X244S, -245I, X246C, X247E, -248I, X249V, -250Y, X251S, -252F, X253D, X254E, -276I, X277V, X278S, X279L, X280L, X281D, -282L, X283P, X284S, -285N, X286V, X287E, -288I, -289K, -291I, X292S, X293R, X294S, X295G, X296V, X297D, X298F, X299I, X300T, X301H, -302I, -303N, -304N, X305K, X306R, X307L, X308T, X309T, -310I, -311L, X312V, -313I, X314A, -315K, X316D, X317N, -318F, -319L, -320K, -321N, X322S, X323T, -324F, X325S, X326G, X327T, -328F, X329I, -330K, X331E, X332N, -333I, -334I, X335W, X336K, X337G, X338I, -339Y, X340T, -341Y, X342R, -343I, X344I, X345K, X346S, X347S, -348F, X349P, X350V, X351P, X352T, -353I, X354K, X355S, X356V, X357T, -358N, X359K, -360K, -361K, -362I, X363C, X364K, -365K, X366H, X367C, X368F, X369V, -370N, X371S, X372Q, -373Y, X374T, X375T, X376R, X377T, X378L, X379S, X380H, -381I, X382L; OPG083: X409D, -410K, -411L, X412T, X413T, -414K, -415L, -416N, X417R, -418I, X419V, X420D, X421D, X422D, X423E, -424*; OPG178: S15F" - } - } - } - ] - }, - { - "name": "NODE_0000063", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6878A", - "C40894T", - "C67724T", - "T145199-", - "G145200-", - "C145201-", - "C145202-", - "A145203-", - "T145204-", - "T145205-", - "T178654-", - "G178655-", - "G178656-", - "A178657-", - "A178658-", - "G178659-", - "A178660-", - "C178661-", - "A178662-", - "T178663-", - "T178664-", - "A178665-", - "C178666-", - "C178667-", - "T178668-", - "A178669-", - "A178670-", - "C178671-" - ], - "OPG060": [ - "G97R" - ], - "OPG085": [ - "E270K" - ], - "OPG167": [ - "K68X", - "W69-", - "H70X", - "*278X" - ] - }, - "labels": { - "aa": "OPG060: G97R; OPG085: E270K; OPG167: K68X, W69-, H70X, *278X" - } - }, - "children": [ - { - "name": "26012023_neck", - "node_attrs": { - "div": 68, - "author": { - "author": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K.", - "value": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2023-01-26" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "26012023_neck" - }, - "strain": { - "value": "OQ672573" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T2640-", - "G2641-", - "T2642-", - "A2643-", - "T2644-", - "T2645-", - "C2646-", - "G2647-", - "T47699-", - "A47700-", - "A47741-", - "T47742-", - "T47743-", - "A47744-", - "G47745-", - "G47746-", - "A47747-", - "C47748-", - "T47749-", - "A47750-", - "C47751-", - "T47752-", - "A47753-", - "C47754-", - "T47755-", - "C47756-", - "T47757-", - "A47758-", - "G47759-", - "A47760-", - "A47761-", - "G47762-", - "A47763-", - "T47764-", - "A47765-", - "T47766-", - "A47767-", - "G47768-", - "C47769-", - "A47770-", - "C47771-", - "C47772-", - "A47773-", - "T47774-", - "C47775-", - "T47776-", - "A47777-", - "T47778-", - "T47779-", - "C47780-", - "C47781-", - "A47782-", - "A47783-", - "A47784-", - "T47785-", - "A47786-", - "A47787-", - "T47788-", - "C47789-", - "A47790-", - "G47791-", - "A47792-", - "A47793-", - "A47794-", - "A47795-", - "C47796-", - "T47797-", - "T47798-", - "A47799-", - "T47800-", - "A47801-", - "A47802-", - "A47803-", - "C47804-", - "T47805-", - "A47806-", - "T47807-", - "T47808-", - "C47809-", - "T47810-", - "C47811-", - "G47812-", - "G47813-", - "A47814-", - "C47815-", - "A47816-", - "T47817-", - "T47818-", - "T47819-", - "C47820-", - "A47821-", - "G47822-", - "T47823-", - "C47824-", - "A47825-", - "T47826-", - "T47827-", - "G47828-", - "G47829-", - "C47830-", - "G47946-", - "A47947-", - "T47948-", - "A47949-", - "T47950-", - "A47951-", - "G47952-", - "T47953-", - "T47954-", - "G47955-", - "A47956-", - "A47957-", - "T47958-", - "C47959-", - "A47960-", - "T47961-", - "G47962-", - "T47963-", - "A47964-", - "T47965-", - "G47966-", - "T48032-", - "T48033-", - "A48034-", - "T48060-", - "A48061-", - "G48062-", - "G48063-", - "A48112-", - "A48113-", - "T48114-", - "A48115-", - "G48116-", - "T48117-", - "A48161-", - "T48162-", - "A48163-", - "G48164-", - "T48165-", - "A48166-", - "G48167-", - "T48168-", - "G48169-", - "T48170-", - "A48171-", - "G48172-", - "T48173-", - "A48174-", - "T48175-", - "C48176-", - "A48177-", - "T48178-", - "A48179-", - "G48180-", - "A48181-", - "T48182-", - "A48183-", - "A48184-", - "C48185-", - "T48186-", - "C48187-", - "T48188-", - "C48189-", - "T48190-", - "T48191-", - "C48192-", - "T48193-", - "A48194-", - "T48195-", - "A48196-", - "A48197-", - "A48198-", - "A48199-", - "A48200-", - "A48201-", - "T48202-", - "G48203-", - "G48204-", - "A48205-", - "T48206-", - "T48207-", - "T48208-", - "T48209-", - "A48210-", - "T48211-", - "T48212-", - "C48213-", - "G48214-", - "T48215-", - "A48216-", - "G48217-", - "A48218-", - "A48219-", - "A48220-", - "G48221-", - "T48222-", - "A48223-", - "T48224-", - "C48225-", - "T48226-", - "A48289-", - "T48290-", - "A48318-", - "A48319-", - "G48320-", - "T48321-", - "A48322-", - "T48323-", - "C48324-", - "T48325-", - "A48326-", - "G48327-", - "T48366-", - "T48382-", - "T48383-", - "T48384-", - "T48385-", - "T48386-", - "G48387-", - "T48388-", - "T48389-", - "T48390-", - "T48391-", - "C48392-", - "A48415-", - "A48416-", - "G48417-", - "T48418-", - "A48419-", - "T48420-", - "A48421-", - "C48422-", - "G48423-", - "A48424-", - "A48425-", - "G48426-", - "C48427-", - "G48428-", - "G48429-", - "T48430-", - "T48431-", - "T48432-", - "A48571-", - "A48572-", - "T48573-", - "A48574-", - "C48575-", - "A48576-", - "T48577-", - "G48578-", - "G48579-", - "A48580-", - "C48581-", - "G48582-", - "A48583-", - "A48584-", - "T48585-", - "T48586-", - "A48587-", - "G48588-", - "G48589-", - "A48590-", - "G48591-", - "A48592-", - "A48593-", - "C48594-", - "T48595-", - "T48596-", - "A48597-", - "T48598-", - "A48599-", - "G48600-", - "G48601-", - "C48602-", - "G48603-", - "T48604-", - "A48605-", - "A48606-", - "A48607-", - "T48608-", - "T48609-", - "A48610-", - "T48611-", - "G48612-", - "A48613-", - "C48614-", - "T48615-", - "T48616-", - "A48617-", - "G48618-", - "T48619-", - "C48648-", - "C48649-", - "C48650-", - "A48651-", - "T48652-", - "C48653-", - "A48654-", - "A48655-", - "A48656-", - "G48657-", - "A48658-", - "T48659-", - "A48660-", - "T48661-", - "G48662-", - "G48663-", - "A48664-", - "A48665-", - "A48666-", - "T48667-", - "C48668-", - "A48669-", - "T48670-", - "T48671-", - "T48672-", - "T48673-", - "T48674-", - "A48760-", - "A48761-", - "G48762-", - "A48763-", - "T48764-", - "A48765-", - "C48766-", - "A48767-", - "G48768-", - "G48769-", - "C48770-", - "A48771-", - "T48772-", - "A48773-", - "G48774-", - "A48775-", - "G48776-", - "T48777-", - "T48778-", - "T48779-", - "G48780-", - "C48781-", - "G48782-", - "G48783-", - "A48784-", - "T48785-", - "A48786-", - "A48787-", - "T48788-", - "A48790T", - "G48798T", - "A48822-", - "C48823-", - "T48824-", - "G48825-", - "G48826-", - "T48827-", - "A48828-", - "G48829-", - "A48830-", - "A48831-", - "T48832-", - "A48833-", - "G48834-", - "T48835-", - "C48836-", - "C48837-", - "A48838-", - "T48839-", - "A48840-", - "G48841-", - "C48842-", - "A48843-", - "A48844-", - "T48845-", - "C48846-", - "T48847-", - "A48848-", - "A48849-", - "C48850-", - "A48851-", - "G48852-", - "A48853-", - "A48854-", - "A48855-", - "C48856-", - "G48857-", - "T48858-", - "T48859-", - "T48860-", - "A48861-", - "G48862-", - "G48863-", - "G48864-", - "A48865-", - "T48866-", - "T48867-", - "A48868-", - "T48869-", - "A48870-", - "T48871-", - "C48872-", - "T48873-", - "T48874-", - "T48875-", - "C48876-", - "C48877T", - "A48909-", - "A48910-", - "C48911-", - "G48912-", - "A48913-", - "A48914-", - "A48915-", - "G48916-", - "T48917-", - "A48918-", - "T48919-", - "T48968-", - "G48969-", - "A48970-", - "T48971-", - "A48972-", - "A48973-", - "A48974-", - "A48975-", - "T48976-", - "T48977-", - "C48978-", - "T48979-", - "T48980-", - "A48981-", - "G48982-", - "T48983-", - "T48984-", - "A48985-", - "T48986-", - "A48987-", - "T48988-", - "A48989-", - "T48990-", - "A48991-", - "C48992-", - "T48993-", - "C48994-", - "T48995-", - "G48996-", - "A48997-", - "G48998-", - "A48999-", - "T49000-", - "A49001-", - "A49002-", - "A49003-", - "A49004-", - "C49005-", - "A49006-", - "G49007-", - "G49008-", - "G49009-", - "A49010-", - "C49011-", - "G49012-", - "C49013-", - "G49014-", - "T49015-", - "T49016-", - "A49017-", - "A49018-", - "T49019-", - "A49020-", - "A49021-", - "A49022-", - "A49023-", - "A49024-", - "C49025-", - "A49026-", - "T49027-", - "G49028-", - "C49029-", - "T49030-", - "T49031-", - "A49032-", - "A49033-", - "G49034-", - "T49035-", - "T49156-", - "T49157-", - "A49158-", - "T49159-", - "T49160-", - "A49161-", - "G49162-", - "T49163-", - "T49164-", - "T49165-", - "T49166-", - "T49167-", - "A49168-", - "C49169-", - "A49170-", - "A49171-", - "A49172-", - "G49173-", - "C49174-", - "T49175-", - "A49176-", - "A49177-", - "T49178-", - "T49179-", - "T49180-", - "T49181-", - "A49182-", - "T49183-", - "T49184-", - "A49185-", - "A49186-", - "C49187-", - "G49188-", - "G49189-", - "T49190-", - "A49191-", - "A49192-", - "T49193-", - "A49194-", - "C49195-", - "A49196-", - "T49197-", - "T49198-", - "T49199-", - "A49200-", - "T49201-", - "T49202-", - "A49203-", - "G49204-", - "T49205-", - "G49206-", - "A49207-", - "T49208-", - "A49209-", - "G49210-", - "A49211-", - "A49212-", - "C49213-", - "G49214-", - "T49215-", - "T49216-", - "T49217-", - "A49218-", - "A49219-", - "C49220-", - "G49221-", - "A49222-", - "T49223-", - "G49224-", - "A49225-", - "C49226-", - "T49227-", - "T49228-", - "A49229-", - "T49230-", - "T49231-", - "C49232-", - "A49233-", - "G49234-", - "A49235-", - "G49236-", - "T49237-", - "T49238-", - "G49239-", - "T49240-", - "T49241-", - "G49242-", - "T49243-", - "T49244-", - "C49245-", - "A49246-", - "A49247-", - "A49248-", - "T49249-", - "A49250-", - "G49251-", - "A49252-", - "T49253-", - "C49254-", - "C49255-", - "C49256-", - "G49257-", - "A49258-", - "A49259-", - "T49260-", - "A49261-", - "T49262-", - "T49263-", - "T49264-", - "C49265-", - "G49266-", - "A49267-", - "T49268-", - "A49269-", - "A49270-", - "T49271-", - "G49272-", - "A49273-", - "A49274-", - "C49275-", - "G49276-", - "A49277-", - "A49278-", - "T49279-", - "T49280-", - "A49281-", - "T49282-", - "G49283-", - "T49284-", - "C49285-", - "T49286-", - "T49287-", - "T49288-", - "A49289-", - "T49290-", - "T49291-", - "C49292-", - "T49293-", - "A49294-", - "T49295-", - "A49296-", - "C49297-", - "G49298-", - "A49299-", - "G49300-", - "T49301-", - "G49302-", - "C49303-", - "T49304-", - "G49305-", - "C49306-", - "G49307-", - "G49308-", - "A49309-", - "C49310-", - "A49311-", - "T49312-", - "T49313-", - "A49314-", - "A49315-", - "A49316-", - "C49317-", - "G49318-", - "A49319-", - "T49320-", - "T49321-", - "T49322-", - "G49323-", - "A49324-", - "T49325-", - "G49326-", - "A49327-", - "G49328-", - "T49329-", - "T49330-", - "A49331-", - "G49332-", - "A49333-", - "T49334-", - "A49335-", - "T49336-", - "T49337-", - "A49338-", - "A49339-", - "T49340-", - "A49341-", - "A49342-", - "C49343-", - "A49344-", - "G49345-", - "T49346-", - "T49347-", - "A49348-", - "T49349-", - "A49350-", - "T49351-", - "A49352-", - "T49353-", - "C49354-", - "T49355-", - "A49356-", - "A49357-", - "G49397-", - "G49398-", - "A49399-", - "T49400-", - "G49401-", - "A49402-", - "T49403-", - "A49404-", - "T49405-", - "G49406-", - "A49407-", - "A49408-", - "G49409-", - "A49410-", - "T49473-", - "T49474-", - "G49475-", - "C49476-", - "A49477-", - "C49478-", - "G49479-", - "A49480-", - "G49481-", - "T49482-", - "C49483-", - "G49484-", - "G49485-", - "A49486-", - "T49487-", - "C49488-", - "C49489-", - "C49490-", - "A49491-", - "T49492-", - "G49493-", - "G49494-", - "T49495-", - "C49496-", - "A49497-", - "T49498-", - "A49499-", - "G49500-", - "A49501-", - "G49502-", - "A49503-", - "A49504-", - "C49505-", - "G49506-", - "G49507-", - "A49508-", - "A49509-", - "T49510-", - "A49511-", - "C49512-", - "T49513-", - "A49514-", - "A49515-", - "A49516-", - "G49517-", - "A49518-", - "A49519-", - "A49520-", - "C49521-", - "T49522-", - "G49523-", - "T49524-", - "C49525-", - "A49526-", - "T49527-", - "C49528-", - "T49529-", - "A49530-", - "T49531-", - "A49532-", - "A49533-", - "A49534-", - "A49535-", - "T49536-", - "C49537-", - "C49538-", - "A49539-", - "A49540-", - "G49541-", - "A49542-", - "G49543-", - "T49544-", - "A49545-", - "G49546-", - "A49547-", - "C49548-", - "G49549-", - "G49550-", - "C49551-", - "T49552-", - "G49553-", - "A49554-", - "A49555-", - "C49556-", - "T49557-", - "T49558-", - "G49559-", - "T49560-", - "T49561-", - "T49562-", - "A49563-", - "G49564-", - "C49565-", - "A49566-", - "A49567-", - "A49568-", - "A49569-", - "A49570-", - "C49571-", - "A49572-", - "T49573-", - "T49574-", - "T49575-", - "T49576-", - "A49577-", - "A49578-", - "A49579-", - "A49580-", - "T49581-", - "A49582-", - "T49583-", - "T49584-", - "A49585-", - "T49586-", - "T49587-", - "T49588-", - "A49589-", - "G49590-", - "A49591-", - "C49592-", - "G49593-", - "G49594-", - "A49595-", - "C49596-", - "A49597-", - "A49598-", - "T49599-", - "T49600-", - "G49601-", - "G49602-", - "C49603-", - "T49604-", - "C49605-", - "G49606-", - "T49607-", - "C49608-", - "T49609-", - "A49610-", - "G49611-", - "G49612-", - "T49613-", - "C49614-", - "T49615-", - "T49616-", - "G49617-", - "T49618-", - "G49619-", - "T49620-", - "T49621-", - "A49622-", - "G49623-", - "A49624-", - "T49625-", - "G49626-", - "A49627-", - "T49628-", - "T49629-", - "A49630-", - "T49631-", - "A49632-", - "A49633-", - "A49634-", - "G49635-", - "G49636-", - "A49637-", - "G49638-", - "A49639-", - "C49640-", - "T49641-", - "T49642-", - "A49643-", - "T49644-", - "T49645-", - "A49646-", - "G49647-", - "T49648-", - "T49649-", - "A49650-", - "A49651-", - "A49652-", - "A49653-", - "T49654-", - "G49655-", - "A49656-", - "T49657-", - "A49658-", - "A49659-", - "A49660-", - "C49661-", - "C49662-", - "A49663-", - "T49664-", - "C49665-", - "T49666-", - "C49667-", - "A49668-", - "A49669-", - "A49670-", - "T49671-", - "C49672-", - "T49673-", - "G49674-", - "T49675-", - "G49676-", - "G49677-", - "A49678-", - "G49679-", - "G49680-", - "A49681-", - "T49682-", - "G49683-", - "T49684-", - "A49685-", - "T49686-", - "C49687-", - "C49688-", - "G49689-", - "C49690-", - "A49691-", - "T49692-", - "T49693-", - "C49694-", - "G49695-", - "T49696-", - "T49697-", - "A49698-", - "G49699-", - "A49700-", - "T49701-", - "T49702-", - "T49703-", - "T49704-", - "C49705-", - "T49706-", - "A49707-", - "C49708-", - "A49709-", - "C62258-", - "A62259-", - "G62260-", - "T62261-", - "T62262-", - "C62305-", - "A62306-", - "A62307-", - "A62308-", - "G62309-", - "C62325-", - "C62326-", - "T62327-", - "A62328-", - "G62329-", - "T62330-", - "T62331-", - "G62332-", - "T62333-", - "A62334-", - "T62335-", - "A62336-", - "C62337-", - "T62338-", - "G62339-", - "A62340-", - "G62341-", - "A62342-", - "A62343-", - "T62344-", - "T62345-", - "G62346-", - "T62372-", - "T62373-", - "T62374-", - "T62375-", - "C62376-", - "A62404-", - "C62405-", - "T62406-", - "G62407-", - "G62408-", - "A62409-", - "A62410-", - "A62411-", - "A62412-", - "C62413-", - "T62414-", - "A62432-", - "A62433-", - "G62434-", - "T62435-", - "A62436-", - "T62437-", - "A62438-", - "T62532-", - "A62533-", - "G62552-", - "A62553-", - "G62554-", - "G62571-", - "C62572-", - "T62573-", - "T62574-", - "C62575-", - "T62576-", - "A62577-", - "G62578-", - "T62599-", - "A62623-", - "C62624-", - "T62625-", - "A62626-", - "T62627-", - "T62643-", - "G62644-", - "G62645-", - "A62646-", - "C62647-", - "T62648-", - "C62649-", - "G62650-", - "C62651-", - "G62652-", - "T62653-", - "T62654-", - "T62655-", - "A62656-", - "G62657-", - "A62658-", - "G62659-", - "G62660-", - "A62661-", - "G62662-", - "T62663-", - "G62664-", - "A62665-", - "A62666-", - "C62667-", - "G62668-", - "T62669-", - "C62670-", - "G62758-", - "T62759-", - "G62760-", - "G62761-", - "A62762-", - "A62763-", - "T62764-", - "T62765-", - "G62766-", - "A62767-", - "A62768-", - "G62769-", - "A62770-", - "T62771-", - "T62772-", - "C62773-", - "T62774-", - "A62775-", - "A62776-", - "T62777-", - "G62778-", - "G62779-", - "A62780-", - "T62781-", - "G62782-", - "A62783-", - "T62784-", - "G62785-", - "T62786-", - "T62787-", - "C62788-", - "T62789-", - "A62790-", - "C62791-", - "C62792-", - "T62793-", - "A62794-", - "T62795-", - "T62796-", - "T62797-", - "C62798-", - "A62799-", - "T62800-", - "C62801-", - "C62802-", - "G62803-", - "A62804-", - "T62805-", - "T62818-", - "C62819-", - "C62820-", - "A62821-", - "G62854-", - "G62855-", - "T62856-", - "A62857-", - "G62858-", - "T62859-", - "C62860-", - "T62861-", - "C62862-", - "T62863-", - "C62864-", - "T62865-", - "T62866-", - "T62867-", - "C62868-", - "G62869-", - "A62892-", - "T62893-", - "A62894-", - "C62895-", - "G62896-", - "A62897-", - "G62898-", - "T62899-", - "C62900-", - "A62901-", - "T62902-", - "T62903-", - "A62904-", - "T62905-", - "A62906-", - "T62907-", - "A62908-", - "C62909-", - "T62910-", - "C62911-", - "C62912-", - "T62931-", - "A62943-", - "T62944-", - "C62945-", - "G62946-", - "A62947-", - "A62965-", - "T62966-", - "C62967-", - "G62968-", - "G62980-", - "A62981-", - "A62982-", - "T62983-", - "C62984-", - "C62985-", - "G62986-", - "G62987-", - "A62988-", - "A62989-", - "C62990-", - "A62991-", - "T62992-", - "T63023-", - "G63024-", - "G63025-", - "T63026-", - "A63027-", - "A63028-", - "G63029-", - "A63030-", - "A63031-", - "A63042-", - "T63075-", - "T63076-", - "G63077-", - "A63078-", - "G63079-", - "A63080-", - "C63081-", - "T63082-", - "T63083-", - "G63084-", - "A63085-", - "T63086-", - "A63102-", - "T63103-", - "T63104-", - "C63143-", - "G63144-", - "T63145-", - "C63146-", - "G63147-", - "A63148-", - "C63149-", - "G63150-", - "C63151-", - "C63152-", - "A63153-", - "A63167-", - "T63168-", - "G63169-", - "G63170-", - "A63171-", - "G63172-", - "T63173-", - "T63239-", - "C63240-", - "T63241-", - "C63242-", - "G63243-", - "T63244-", - "A63245-", - "C63246-", - "G63247-", - "T63255-", - "T63256-", - "C63257-", - "C63258-", - "A63259-", - "T63260-", - "G63261-", - "A63262-", - "T63263-", - "C63264-", - "A63265-", - "A63266-", - "G63267-", - "A63268-", - "G63269-", - "T63270-", - "G63271-", - "A63272-", - "T63273-", - "T63274-", - "T63275-", - "G63276-", - "A63277-", - "G63278-", - "A63279-", - "A63280-", - "C63281-", - "A63282-", - "T63283-", - "C63284-", - "C63285-", - "A63311-", - "C63312-", - "A63313-", - "G63314-", - "T63315-", - "T63328-", - "A63329-", - "A63330-", - "T63331-", - "T63347-", - "A63348-", - "C63365-", - "G63366-", - "T63367-", - "T63368-", - "T63369-", - "A63370-", - "A63371-", - "T63385-", - "C63386-", - "T63387-", - "A63388-", - "A63389-", - "C63390-", - "G63391-", - "G63392-", - "A63393-", - "G63394-", - "A63395-", - "C63396-", - "A63397-", - "A63398-", - "T63399-", - "T63400-", - "T63401-", - "T63402-", - "T63403-", - "T63404-", - "G63405-", - "G63406-", - "T63407-", - "A63408-", - "G63409-", - "G63410-", - "T63411-", - "T63412-", - "T63413-", - "T63414-", - "A63415-", - "G63416-", - "A63417-", - "G63418-", - "A63419-", - "C63420-", - "T63421-", - "T63422-", - "T63423-", - "G63424-", - "A63425-", - "A63426-", - "G63427-", - "C63428-", - "T63429-", - "A63430-", - "C63431-", - "T63432-", - "T63433-", - "G63434-", - "T63435-", - "T63436-", - "T63437-", - "A63438-", - "A63439-", - "C63440-", - "A63441-", - "A63442-", - "A63443-", - "G63444-", - "T63445-", - "T63446-", - "A63447-", - "T63448-", - "T63449-", - "C63450-", - "A63451-", - "T63452-", - "C63453-", - "G63454-", - "T63455-", - "C63456-", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T178558-", - "G178559-", - "A178560-", - "T178561-", - "T178562-", - "A178563-", - "T178564-", - "A178565-", - "C178566-", - "A178567-", - "T178568-", - "C178569-", - "G178570-", - "G178571-", - "T178572-", - "A178573-", - "C178574-", - "A178575-", - "T178576-", - "A178577-", - "C178578-", - "A178579-", - "G178580-", - "T178581-", - "A178582-", - "A178583-", - "A178584-", - "T178585-", - "A178586-", - "G178587-", - "C178588-", - "A178589-", - "T178590-", - "A178591-", - "G178592-", - "A178593-", - "T178594-", - "A178595-", - "T178596-", - "G178597-", - "G178598-", - "A178599-", - "G178600-", - "G178601-", - "A178602-", - "G178603-", - "G178604-", - "A178605-", - "T178606-", - "A178607-", - "C178608-", - "A178609-", - "A178610-", - "A178611-", - "T178612-", - "A178613-", - "T178614-", - "T178615-", - "T178616-", - "C178617-", - "A178618-", - "A178619-", - "A178620-", - "T178621-", - "A178622-", - "A178623-", - "A178624-", - "G178625-", - "T178626-", - "T178627-", - "A178628-", - "T178629-", - "G178630-", - "A178631-", - "G178632-", - "A178633-", - "T178634-", - "A178635-", - "C178636-", - "G178637-", - "C178638-", - "G178639-", - "C178640-", - "T178641-", - "G178642-", - "T178643-", - "C178644-", - "A178645-", - "A178646-", - "T178647-", - "A178648-", - "A178649-", - "T178650-", - "A178651-", - "T178652-", - "A178653-", - "T178672-", - "T178673-", - "C178674-", - "T178675-", - "G178676-", - "A178677-", - "A178678-", - "C178679-", - "T178680-", - "G178681-", - "G178682-", - "A178683-", - "A178684-", - "C178685-", - "T178686-", - "A178687-", - "T178688-", - "A178689-", - "A178690-", - "A178691-", - "T178692-", - "C178693-", - "C178694-", - "A178695-", - "G178696-", - "G178697-", - "C178698-", - "T178699-", - "C178700-", - "T178701-", - "C178702-", - "G178703-", - "C178704-", - "A178705-", - "T178706-", - "A178707-", - "A178708-", - "A178709-", - "G178710-", - "A178711-", - "T178712-", - "G178713-", - "A178714-", - "A178715-", - "T178716-", - "A178717-", - "T178718-", - "A178719-", - "T178720-", - "A178721-", - "T178722-", - "G178723-", - "T178724-", - "T178725-", - "G178726-", - "T178727-", - "A178728-", - "T178729-", - "G178730-", - "C178731-", - "G178732-", - "A178733-", - "C178734-", - "A178735-", - "T178736-", - "C178737-", - "A178738-", - "A178739-", - "A178740-", - "G178741-", - "A178742-", - "T178743-", - "G178744-", - "A178745-", - "A178746-", - "A178747-", - "A178748-", - "A178749-", - "A178750-", - "T178751-", - "G178752-", - "T178753-", - "T178754-", - "A178755-", - "A178756-", - "G178757-", - "A178758-", - "C178759-", - "T178760-", - "T178761-", - "A178762-", - "T178763-", - "A178764-", - "T178765-", - "A178766-", - "T178767-", - "T178768-", - "T178769-", - "A178770-", - "G178771-", - "A178772-", - "T178773-", - "A178774-", - "T178775-", - "A178776-", - "A178777-", - "C178778-", - "A178779-", - "C178780-", - "G178781-", - "A178782-", - "A178783-", - "T178784-", - "A178785-", - "T178786-", - "G178787-", - "T178788-", - "A178789-", - "T178790-", - "G178791-", - "A178792-", - "C178793-", - "G178794-", - "G178795-", - "A178796-", - "T178797-", - "G178798-", - "G178799-", - "G178800-", - "A178801-", - "A178802-", - "T178803-", - "T178804-", - "G178805-", - "G178806-", - "T178807-", - "A178808-", - "A178809-", - "C178810-", - "G178811-", - "A178812-", - "T178813-", - "G178814-", - "A178815-", - "C178816-", - "A178817-", - "G178818-", - "A178819-", - "A178820-", - "A178821-", - "G178822-", - "C178823-", - "A178824-", - "G178825-", - "A178826-", - "T178827-", - "T178828-", - "G178829-", - "T178830-", - "C178831-", - "A178832-", - "G178833-", - "C178834-", - "T178835-", - "C178836-", - "T178837-", - "G178838-", - "C178839-", - "A178840-", - "T178841-", - "A178842-", - "C178843-", - "T178844-", - "A178845-", - "T178846-", - "T178847-", - "C178848-", - "T178849-", - "T178850-", - "C178851-", - "A178852-", - "T178853-", - "G178854-", - "A178855-", - "C178856-", - "A178857-", - "A178858-", - "T178859-", - "A178860-", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-", - "G178879-", - "T178880-", - "T178881-", - "A178882-", - "T178883-", - "G178884-", - "A178885-", - "A178886-", - "G178887-", - "C178888-", - "G178889-", - "T178890-", - "A178891-", - "T178892-", - "A178893-", - "T178894-", - "G178895-", - "T178896-", - "T178897-", - "A178898-", - "C178899-", - "A178900-", - "A178901-", - "G178902-", - "A178903-", - "T178904-", - "A178905-", - "C178906-", - "A178907-", - "T178908-", - "T178909-", - "T178910-", - "A178911-", - "A178912-", - "T178913-", - "G178914-", - "T178915-", - "G178916-" - ], - "OPG068": [ - "M1-", - "D2-", - "F3-", - "I4-", - "R5-", - "R6-", - "K7-", - "Y8-", - "L9X", - "N30X", - "K40-", - "Y41-", - "L42-", - "V43X", - "L56X", - "F61X", - "F62-", - "V63-", - "F64-", - "K72X", - "V73-", - "Y74-", - "E75-", - "A76-", - "V77-", - "L78X", - "E124X", - "Y125-", - "M126-", - "D127-", - "E128-", - "L129-", - "G130-", - "E131-", - "L132-", - "I133-", - "G134-", - "V135-", - "N136-", - "Y137-", - "D138-", - "L139-", - "V140X", - "P150-", - "I151-", - "K152-", - "D153-", - "M154-", - "E155-", - "I156-", - "I157-", - "F158-", - "K187X", - "D188-", - "T189-", - "G190-", - "I191-", - "E192-", - "F193-", - "A194-", - "D195-", - "N196-", - "D197V", - "D200Y", - "T208-", - "G209-", - "R210-", - "I211-", - "V212-", - "H213-", - "S214-", - "N215-", - "L216-", - "T217-", - "E218-", - "T219-", - "F220-", - "R221-", - "D222-", - "Y223-", - "I224-", - "F225-", - "P226X", - "N237-", - "E238-", - "S239-", - "I240X", - "Y256X", - "D257-", - "K258-", - "I259-", - "L260-", - "S261-", - "Y262-", - "I263-", - "Y264-", - "S265-", - "E266-", - "I267-", - "K268-", - "Q269-", - "G270-", - "R271-", - "V272-", - "N273-", - "K274-", - "N275-", - "M276-", - "L277-", - "K278-", - "L279X", - "F319X", - "I320-", - "S321-", - "F322-", - "Y323-", - "K324-", - "A325-", - "N326-", - "F327-", - "I328-", - "N329-", - "G330-", - "N331-", - "T332-", - "F333-", - "I334-", - "S335-", - "D336-", - "R337-", - "T338-", - "F339-", - "N340-", - "D341-", - "D342-", - "L343-", - "F344-", - "R345-", - "V346-", - "V347-", - "V348-", - "Q349-", - "I350-", - "D351-", - "P352-", - "E353-", - "Y354-", - "F355-", - "D356-", - "N357-", - "E358-", - "R359-", - "I360-", - "M361-", - "S362-", - "L363-", - "F364-", - "Y365-", - "T366-", - "S367-", - "A368-", - "A369-", - "D370-", - "I371-", - "K372-", - "R373-", - "F374-", - "D375-", - "E376-", - "L377-", - "D378-", - "I379-", - "N380-", - "N381-", - "S382-", - "Y383-", - "I384-", - "S385-", - "N386X", - "M399X", - "D400-", - "D401-", - "M402-", - "K403-", - "K404X", - "L425-", - "H426-", - "E427-", - "S428-", - "D429-", - "P430-", - "M431-", - "V432-", - "I433-", - "E434-", - "N435-", - "G436-", - "I437-", - "L438-", - "K439-", - "K440-", - "L441-", - "S442-", - "S443-", - "I444-", - "K445-", - "S446-", - "K447-", - "S448-", - "R449-", - "R450-", - "L451-", - "N452-", - "L453-", - "F454-", - "S455-", - "K456-", - "N457-", - "I458-", - "L459-", - "K460-", - "Y461-", - "Y462-", - "L463-", - "D464-", - "G465-", - "Q466-", - "L467-", - "A468-", - "R469-", - "L470-", - "G471-", - "L472-", - "V473-", - "L474-", - "D475-", - "D476-", - "Y477-", - "K478-", - "G479-", - "D480-", - "L481-", - "L482-", - "V483-", - "K484-", - "M485-", - "I486-", - "N487-", - "H488-", - "L489-", - "K490-", - "S491-", - "V492-", - "E493-", - "D494-", - "V495-", - "S496-", - "A497-", - "F498-", - "V499-", - "R500-", - "F501-", - "S502-", - "T503-", - "*568X" - ], - "OPG081": [ - "L8X", - "T9-", - "A10X", - "*80X" - ], - "OPG082": [ - "M1-", - "N2-", - "N3-", - "F4-", - "V5-", - "K6-", - "Q7-", - "V8-", - "A9-", - "S10-", - "K11-", - "S12-", - "L13-", - "K14-", - "P15-", - "T16-", - "K17-", - "K18-", - "L19-", - "S20-", - "P21-", - "L22-", - "D23X", - "L28-", - "N29-", - "E30X", - "F35X", - "N36X", - "Y41X", - "Y42X", - "G46X", - "L47-", - "F48X", - "E56X", - "D57-", - "V58-", - "L59-", - "K60-", - "S61-", - "L62-", - "L63-", - "I64-", - "M65-", - "E66-", - "A69X", - "Y70-", - "E71-", - "K72X", - "T94-", - "P95-", - "F96X", - "T100X", - "G101-", - "V102-", - "D103-", - "D104X", - "N117-", - "I123-", - "K124-", - "S125-", - "Q126-", - "N137X", - "V141X", - "L142-", - "T143-", - "T144X", - "N154X", - "V155-", - "P156-", - "D157-", - "S158X", - "S162X", - "I163X", - "F169X", - "D170-", - "I174X", - "G181-", - "V182-", - "Y183-", - "N184-", - "D185-", - "S186-", - "Y187-", - "P195X", - "K196-", - "E197-", - "R198-", - "L199-", - "P200X", - "L211X", - "E212X", - "L216X", - "S217-", - "D218-", - "E219-", - "I220-", - "G221-", - "R222-", - "T223-", - "S224-", - "S225-", - "I226-", - "R227-", - "I228-", - "F229-", - "N230-", - "S231-", - "T232X", - "K261X", - "T262-", - "F263-", - "T264-", - "P265-", - "L266-", - "N267-", - "A268-", - "S269-", - "P270-", - "I276-", - "V277X", - "N285X", - "S292X", - "R293-", - "S294-", - "T300X", - "H301X", - "L307X", - "Y339-", - "T340-", - "Y341X", - "S347-", - "F348-", - "P349-", - "V350X", - "K359X", - "K360-", - "K361X", - "V369X", - "N370-", - "S371-", - "Q372-", - "Y373-", - "T374-", - "T375-", - "R376-", - "L382-", - "*383X" - ], - "OPG083": [ - "D421-", - "D422-", - "E423-", - "*424-" - ] - }, - "labels": { - "aa": "OPG068: M1-, D2-, F3-, I4-, R5-, R6-, K7-, Y8-, L9X, N30X, K40-, Y41-, L42-, V43X, L56X, F61X, F62-, V63-, F64-, K72X, V73-, Y74-, E75-, A76-, V77-, L78X, E124X, Y125-, M126-, D127-, E128-, L129-, G130-, E131-, L132-, I133-, G134-, V135-, N136-, Y137-, D138-, L139-, V140X, P150-, I151-, K152-, D153-, M154-, E155-, I156-, I157-, F158-, K187X, D188-, T189-, G190-, I191-, E192-, F193-, A194-, D195-, N196-, D197V, D200Y, T208-, G209-, R210-, I211-, V212-, H213-, S214-, N215-, L216-, T217-, E218-, T219-, F220-, R221-, D222-, Y223-, I224-, F225-, P226X, N237-, E238-, S239-, I240X, Y256X, D257-, K258-, I259-, L260-, S261-, Y262-, I263-, Y264-, S265-, E266-, I267-, K268-, Q269-, G270-, R271-, V272-, N273-, K274-, N275-, M276-, L277-, K278-, L279X, F319X, I320-, S321-, F322-, Y323-, K324-, A325-, N326-, F327-, I328-, N329-, G330-, N331-, T332-, F333-, I334-, S335-, D336-, R337-, T338-, F339-, N340-, D341-, D342-, L343-, F344-, R345-, V346-, V347-, V348-, Q349-, I350-, D351-, P352-, E353-, Y354-, F355-, D356-, N357-, E358-, R359-, I360-, M361-, S362-, L363-, F364-, Y365-, T366-, S367-, A368-, A369-, D370-, I371-, K372-, R373-, F374-, D375-, E376-, L377-, D378-, I379-, N380-, N381-, S382-, Y383-, I384-, S385-, N386X, M399X, D400-, D401-, M402-, K403-, K404X, L425-, H426-, E427-, S428-, D429-, P430-, M431-, V432-, I433-, E434-, N435-, G436-, I437-, L438-, K439-, K440-, L441-, S442-, S443-, I444-, K445-, S446-, K447-, S448-, R449-, R450-, L451-, N452-, L453-, F454-, S455-, K456-, N457-, I458-, L459-, K460-, Y461-, Y462-, L463-, D464-, G465-, Q466-, L467-, A468-, R469-, L470-, G471-, L472-, V473-, L474-, D475-, D476-, Y477-, K478-, G479-, D480-, L481-, L482-, V483-, K484-, M485-, I486-, N487-, H488-, L489-, K490-, S491-, V492-, E493-, D494-, V495-, S496-, A497-, F498-, V499-, R500-, F501-, S502-, T503-, *568X; OPG081: L8X, T9-, A10X, *80X; OPG082: M1-, N2-, N3-, F4-, V5-, K6-, Q7-, V8-, A9-, S10-, K11-, S12-, L13-, K14-, P15-, T16-, K17-, K18-, L19-, S20-, P21-, L22-, D23X, L28-, N29-, E30X, F35X, N36X, Y41X, Y42X, G46X, L47-, F48X, E56X, D57-, V58-, L59-, K60-, S61-, L62-, L63-, I64-, M65-, E66-, A69X, Y70-, E71-, K72X, T94-, P95-, F96X, T100X, G101-, V102-, D103-, D104X, N117-, I123-, K124-, S125-, Q126-, N137X, V141X, L142-, T143-, T144X, N154X, V155-, P156-, D157-, S158X, S162X, I163X, F169X, D170-, I174X, G181-, V182-, Y183-, N184-, D185-, S186-, Y187-, P195X, K196-, E197-, R198-, L199-, P200X, L211X, E212X, L216X, S217-, D218-, E219-, I220-, G221-, R222-, T223-, S224-, S225-, I226-, R227-, I228-, F229-, N230-, S231-, T232X, K261X, T262-, F263-, T264-, P265-, L266-, N267-, A268-, S269-, P270-, I276-, V277X, N285X, S292X, R293-, S294-, T300X, H301X, L307X, Y339-, T340-, Y341X, S347-, F348-, P349-, V350X, K359X, K360-, K361X, V369X, N370-, S371-, Q372-, Y373-, T374-, T375-, R376-, L382-, *383X; OPG083: D421-, D422-, E423-, *424-" - } - } - }, - { - "name": "02022023_gluteal", - "node_attrs": { - "div": 67, - "author": { - "author": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K.", - "value": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2023-02-02" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "02022023_gluteal" - }, - "strain": { - "value": "OQ672575" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A125538G", - "G152986A" - ], - "OPG180": [ - "E99K" - ] - }, - "labels": { - "aa": "OPG180: E99K" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000064", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C141757T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - }, - "children": [ - { - "name": "HRYC_MPXV001", - "node_attrs": { - "div": 66, - "author": { - "author": "Ponce-Alonso,M., Martinez-Garcia,L., Olavarrieta,L., Galan,J.C.", - "value": "Ponce-Alonso,M., Martinez-Garcia,L., Olavarrieta,L., Galan,J.C." - }, - "country": { - "value": "Spain" - }, - "date": { - "value": "2022-09-21" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Hospital Ramon y Cajal, Microbiology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "HRYC_MPXV001" - }, - "strain": { - "value": "OR126131" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C11747-", - "C34432T", - "C48324T", - "G101294A", - "G190695A" - ], - "NBT03_gp174": [ - "E96K" - ], - "OPG023": [ - "G385X", - "*661X" - ], - "OPG053": [ - "E87K" - ], - "OPG120": [ - "S152L" - ] - }, - "labels": { - "aa": "NBT03_gp174: E96K; OPG023: G385X, *661X; OPG053: E87K; OPG120: S152L" - } - } - }, - { - "name": "NODE_0000065", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.18" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C43706T", - "T124690C" - ] - }, - "labels": { - "clade": "B.1.18" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-083401/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-083401/2022" - }, - "strain": { - "value": "OP628451" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.18" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NY-NYCPHL-000448", - "node_attrs": { - "div": 69, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-21" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000448" - }, - "strain": { - "value": "OQ468880" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.18" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G24063A", - "C25370T", - "G54088A", - "G108462A", - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C164810T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG039": [ - "S19F" - ], - "OPG040": [ - "E37K" - ], - "OPG189": [ - "S493F" - ] - }, - "labels": { - "aa": "OPG039: S19F; OPG040: E37K; OPG189: S493F" - } - } - }, - { - "name": "NY-NYCPHL-000983", - "node_attrs": { - "div": 65, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-11" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000983" - }, - "strain": { - "value": "OQ565541" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.18" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C127388T", - "T133078-", - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG149": [ - "R65C" - ] - }, - "labels": { - "aa": "OPG149: R65C" - } - } - }, - { - "name": "NODE_0000066", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.18" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G67758A", - "C170049T" - ] - } - }, - "children": [ - { - "name": "VAC_INS_MPX_0965_EL", - "node_attrs": { - "div": 67, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-10-12" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "VAC_INS_MPX_0965_EL" - }, - "strain": { - "value": "OP819956" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.18" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G28913A", - "A196376-", - "T196377-", - "C196378-" - ], - "OPG045": [ - "S117L" - ] - }, - "labels": { - "aa": "OPG045: S117L" - } - } - }, - { - "name": "LBMB-UTP_MP-025_VAC", - "node_attrs": { - "div": 70, - "author": { - "author": "Lopez,P.A., Orjuela,M., Tabares,F.A., Anacona,J.D., Zuluaga-Velez,A., Sepulveda-Arias,J.C.", - "value": "Lopez,P.A., Orjuela,M., Tabares,F.A., Anacona,J.D., Zuluaga-Velez,A., Sepulveda-Arias,J.C." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-11-15" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "LBMB-UTP_MP-025_VAC" - }, - "strain": { - "value": "OQ148474" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.18" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C128242T", - "G144572A", - "C166940T", - "C168829T" - ], - "OPG150": [ - "S155F" - ] - }, - "labels": { - "aa": "OPG150: S155F" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000067", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C9389T", - "G161797A", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-", - "A185557C" - ], - "OPG188": [ - "E68K" - ], - "OPG210": [ - "K1401T" - ] - }, - "labels": { - "aa": "OPG188: E68K; OPG210: K1401T", - "clade": "B.1.16" - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-24561-E", - "node_attrs": { - "div": 65, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-09-07" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-24561-E" - }, - "strain": { - "value": "OP642395" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G161421A" - ], - "OPG187": [ - "R267K" - ] - }, - "labels": { - "aa": "OPG187: R267K" - } - } - }, - { - "name": "NODE_0000068", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C30154T" - ] - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-23596-O", - "node_attrs": { - "div": 66, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-08-29" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-23596-O" - }, - "strain": { - "value": "OP459211" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G170076A" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-24909-C", - "node_attrs": { - "div": 67, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-09-09" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-24909-C" - }, - "strain": { - "value": "OP642383" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6863A", - "C132608T" - ] - } - } - }, - { - "name": "DC_INS_MPX_0082_L", - "node_attrs": { - "div": 65, - "author": { - "author": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M.", - "value": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-08-08" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "DC_INS_MPX_0082_L" - }, - "strain": { - "value": "OP693647" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A356-", - "C357-", - "A358-", - "T195509-", - "A195510-", - "A195511-" - ] - } - } - }, - { - "name": "DC_INS_MPX_0719_L", - "node_attrs": { - "div": 66, - "author": { - "author": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M.", - "value": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-08-29" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "DC_INS_MPX_0719_L" - }, - "strain": { - "value": "OP693653" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G121275A" - ], - "OPG139": [ - "P32S" - ] - }, - "labels": { - "aa": "OPG139: P32S" - } - } - }, - { - "name": "CUN_INS_MPX_1053_L", - "node_attrs": { - "div": 68, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-10-27" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "CUN_INS_MPX_1053_L" - }, - "strain": { - "value": "OP837472" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A51023G", - "C125610T", - "C157551T", - "-178536T", - "-178537A", - "-178538T", - "-178539A", - "-178540A", - "-178541G", - "-178542C", - "-178543G", - "-178544G", - "-178545T", - "-178546C", - "-178547G", - "-178548T", - "-178549A", - "-178550C", - "-178551C", - "-178552C", - "-178553A" - ], - "OPG070": [ - "N145S" - ], - "OPG146": [ - "M10I" - ] - }, - "labels": { - "aa": "OPG070: N145S; OPG146: M10I" - } - } - }, - { - "name": "DC_INS_MPX-1119-H", - "node_attrs": { - "div": 66, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Rosales,A., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Rosales,A., Mercado-Reyes,M.M." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-10-24" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "DC_INS_MPX-1119-H" - }, - "strain": { - "value": "OQ197862" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G574-", - "A575-", - "G576-", - "G23118A", - "-178536T", - "-178537A", - "-178538T", - "-178539A", - "-178540A", - "-178541G", - "-178542C", - "-178543G", - "-178544G", - "-178545T", - "-178546C", - "-178547G", - "-178548T", - "-178549A", - "-178550C", - "-178551C", - "-178552C", - "-178553A", - "A196376-", - "T196377-", - "C196378-" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-30094O", - "node_attrs": { - "div": 68, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-11-08" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-30094O" - }, - "strain": { - "value": "OQ696095" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T548-", - "A549-", - "A550-", - "G104597A", - "C116175T", - "G148403A", - "G150585A", - "-178536T", - "-178537A", - "-178538T", - "-178539A", - "-178540A", - "-178541G", - "-178542C", - "-178543G", - "-178544G", - "-178545T", - "-178546C", - "-178547G", - "-178548T", - "-178549A", - "-178550C", - "-178551C", - "-178552C", - "-178553A" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-30280C", - "node_attrs": { - "div": 68, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-11-08" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-30280C" - }, - "strain": { - "value": "OQ696096" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.16" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G23673A", - "G37974A", - "A164477G", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "-178536T", - "-178537A", - "-178538T", - "-178539A", - "-178540A", - "-178541G", - "-178542C", - "-178543G", - "-178544G", - "-178545T", - "-178546C", - "-178547G", - "-178548T", - "-178549A", - "-178550C", - "-178551C", - "-178552C", - "-178553A" - ], - "OPG039": [ - "S149L" - ], - "OPG056": [ - "S354L" - ], - "OPG189": [ - "E382G" - ] - }, - "labels": { - "aa": "OPG039: S149L; OPG056: S354L; OPG189: E382G" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000078", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A11326-", - "T11327-", - "C11328-", - "T11329-", - "A11330-", - "C11331-", - "G11332-", - "A11333-", - "T11334-", - "A11335-", - "T11336-", - "T11337-", - "A11338-", - "G11339-", - "A11340-", - "T11341-", - "A11342-", - "C11343-", - "T11344-", - "T11345-", - "C11346-", - "A11347-", - "C11348-", - "T11349-", - "C11350-", - "A11351-", - "A11352-", - "T11353-", - "G11354-", - "A11355-", - "A11356-", - "T11357-", - "C11358-", - "A11359-", - "A11360-", - "T11361-", - "C11362-", - "A11363-", - "C11364-", - "A11365-", - "C11366-", - "A11367-", - "A11368-", - "T11369-", - "C11370-", - "T11371-", - "A11372-", - "A11373-", - "T11374-", - "G11375-", - "T11376-", - "A11377-", - "G11378-", - "G11379-", - "T11380-", - "T11381-", - "T11382-", - "A11383-", - "T11384-", - "G11385-", - "A11386-", - "C11387-", - "A11388-", - "T11389-", - "A11390-", - "A11391-", - "T11392-", - "A11393-", - "G11394-", - "C11395-", - "A11396-", - "T11397-", - "T11398-", - "T11399-", - "T11400-", - "C11401-", - "A11402-", - "G11403-", - "C11404-", - "A11405-", - "G11406-", - "T11407-", - "T11408-", - "C11409-", - "A11410-", - "A11411-", - "T11412-", - "G11413-", - "T11414-", - "T11415-", - "T11416-", - "C11417-", - "T11418-", - "A11419-", - "G11420-", - "A11421-", - "T11422-", - "T11423-", - "C11424-", - "G11425-", - "T11426-", - "T11427-", - "G11428-", - "A11429-", - "T11430-", - "G11431-", - "G11432-", - "C11433-", - "A11434-", - "A11435-", - "T11436-", - "G11437-", - "G11438-", - "T11439-", - "T11440-", - "A11441-", - "T11442-", - "A11443-", - "C11444-", - "A11445-", - "T11446-", - "G11447-", - "T11448-", - "A11449-", - "T11450-", - "A11451-", - "T11452-", - "C11453-", - "C11454-", - "G11455-", - "T11456-", - "T11457-", - "A11458-", - "T11459-", - "T11460-", - "T11461-", - "G11462-", - "A11463-", - "T11464-", - "C11465-", - "T11466-", - "A11467-", - "A11468-", - "T11469-", - "G11470-", - "T11471-", - "T11472-", - "G11473-", - "A11474-", - "C11475-", - "A11476-", - "T11477-", - "C11478-", - "T11479-", - "G11480-", - "A11481-", - "A11482-", - "C11483-", - "C11484-", - "G11485-", - "G11486-", - "A11487-", - "T11488-", - "T11489-", - "C11490-", - "T11491-", - "A11492-", - "G11493-", - "C11494-", - "A11495-", - "G11496-", - "T11497-", - "A11498-", - "A11499-", - "A11500-", - "G11501-", - "A11502-", - "T11503-", - "A11504-", - "C11505-", - "T11506-", - "A11507-", - "G11508-", - "A11509-", - "G11510-", - "A11511-", - "T11512-", - "T11513-", - "G11514-", - "T11515-", - "T11516-", - "T11517-", - "A11518-", - "T11519-", - "T11520-", - "A11521-", - "T11522-", - "A11523-", - "T11524-", - "C11525-", - "T11526-", - "A11527-", - "A11528-", - "C11529-", - "A11530-", - "G11531-", - "C11532-", - "C11533-", - "T11534-", - "T11535-", - "G11536-", - "T11537-", - "G11538-", - "A11539-", - "A11540-", - "G11541-", - "A11542-", - "A11543-", - "G11544-", - "T11545-", - "G11546-", - "T11547-", - "T11548-", - "T11549-", - "C11550-", - "T11551-", - "C11552-", - "C11553-", - "T11554-", - "C11555-", - "G11556-", - "T11557-", - "T11558-", - "T11559-", - "G11560-", - "T11561-", - "C11562-", - "A11563-", - "A11564-", - "T11565-", - "C11566-", - "A11567-", - "T11568-", - "G11569-", - "T11570-", - "T11571-", - "A11572-", - "A11573-", - "T11574-", - "G11575-", - "T11576-", - "C11577-", - "T11578-", - "T11579-", - "T11580-", - "A11581-", - "A11582-", - "G11583-", - "A11584-", - "T11585-", - "A11586-", - "A11587-", - "G11588-", - "G11589-", - "T11590-", - "A11591-", - "G11592-", - "A11593-", - "C11594-", - "A11595-", - "A11596-", - "A11597-", - "T11598-", - "G11599-", - "T11600-", - "T11601-", - "T11602-", - "A11603-", - "T11604-", - "A11605-", - "G11606-", - "T11607-", - "A11608-", - "C11609-", - "T11610-", - "A11611-", - "A11612-", - "G11613-", - "A11614-", - "A11615-", - "T11616-", - "T11617-", - "G11618-", - "G11619-", - "G11620-", - "C11621-", - "A11622-", - "A11623-", - "A11624-", - "C11625-", - "A11626-", - "T11627-", - "A11628-", - "A11629-", - "G11630-", - "A11631-", - "C11632-", - "A11633-", - "T11634-", - "G11635-", - "T11636-", - "C11637-", - "A11638-", - "C11639-", - "A11640-", - "A11641-", - "A11642-", - "G11643-", - "A11644-", - "C11645-", - "C11646-", - "C11647-", - "T11648-", - "T11649-", - "T11650-", - "T11651-", - "T11652-", - "G11653-", - "T11654-", - "A11655-", - "T11656-", - "G11657-", - "T11658-", - "A11659-", - "T11660-", - "A11661-", - "A11662-", - "G11663-", - "T11664-", - "G11665-", - "T11666-", - "A11667-", - "G11668-", - "A11669-", - "A11670-", - "A11671-", - "T11672-", - "T11673-", - "A11674-", - "T11675-", - "A11676-", - "A11677-", - "C11678-", - "A11679-", - "T11680-", - "C11681-", - "C11682-", - "A11683-", - "T11684-", - "A11685-", - "G11686-", - "T11687-", - "T11688-", - "G11689-", - "G11690-", - "A11691-", - "T11692-", - "T11693-", - "C11694-", - "A11695-", - "C11696-", - "A11697-", - "T11698-", - "A11699-", - "G11700-", - "G11701-", - "T11702-", - "G11703-", - "T11704-", - "C11705-", - "C11706-", - "A11707-", - "A11708-", - "T11709-", - "C11710-", - "G11711-", - "G11712-", - "G11713-", - "A11714-", - "T11715-", - "C11716-", - "T11717-", - "C11718-", - "T11719-", - "C11720-", - "C11721-", - "A11722-", - "T11723-", - "C11724-", - "A11725-", - "T11726-", - "C11727-", - "G11728-", - "A11729-", - "G11730-", - "A11731-", - "T11732-", - "G11733-", - "A11734-", - "T11735-", - "T11736-", - "G11737-", - "A11738-", - "C11739-", - "G11740-", - "G11741-", - "C11742-", - "A11743-", - "T11744-", - "C11745-", - "T11746-", - "C11747-", - "C11748-", - "C11749-", - "C11750-", - "C11751-", - "T11752-", - "T11753-", - "C11754-", - "C11755-", - "T11756-", - "T11757-", - "T11758-", - "T11759-", - "T11760-", - "T11761-", - "A11762-", - "G11763-", - "T11764-", - "A11765-", - "G11766-", - "A11767-", - "T11768-", - "A11769-", - "T11770-", - "T11771-", - "T11772-", - "C11773-", - "A11774-", - "T11775-", - "C11776-", - "G11777-", - "T11778-", - "G11779-", - "T11780-", - "A11781-", - "A11782-", - "G11783-", - "A11784-", - "A11785-", - "T11786-", - "C11787-", - "A11788-", - "A11789-", - "T11790-", - "A11791-", - "T11792-", - "T11793-", - "A11794-", - "A11795-", - "T11796-", - "A11797-", - "T11798-", - "T11799-", - "T11800-", - "C11801-", - "T11802-", - "A11803-", - "A11804-", - "A11805-", - "G11806-", - "T11807-", - "A11808-", - "T11809-", - "C11810-", - "T11811-", - "G11812-", - "T11813-", - "G11814-", - "T11815-", - "A11816-", - "T11817-", - "A11818-", - "G11819-", - "C11820-", - "C11821-", - "T11822-", - "C11823-", - "T11824-", - "T11825-", - "T11826-", - "A11827-", - "T11828-", - "T11829-", - "T11830-", - "A11831-", - "C11832-", - "C11833-", - "A11834-", - "C11835-", - "A11836-", - "G11837-", - "C11838-", - "T11839-", - "C11840-", - "C11841-", - "A11842-", - "T11843-", - "A11844-", - "T11845-", - "T11846-", - "C11847-", - "C11848-", - "A11849-", - "A11850-", - "C11851-", - "A11852-", - "T11853-", - "G11854-", - "C11855-", - "A11856-", - "T11857-", - "T11858-", - "C11859-", - "C11860-", - "A11861-", - "C11862-", - "T11863-", - "A11864-", - "G11865-", - "A11866-", - "G11867-", - "G11868-", - "G11869-", - "A11870-", - "T11871-", - "A11872-", - "T11873-", - "C11874-", - "G11875-", - "A11876-", - "T11877-", - "A11878-", - "T11879-", - "C11880-", - "G11881-", - "C11882-", - "C11883-", - "G11884-", - "A11885-", - "A11886-", - "T11887-", - "G11888-", - "T11889-", - "C11890-", - "A11891-", - "T11892-", - "A11893-", - "T11894-", - "A11895-", - "C11896-", - "T11897-", - "C11898-", - "A11899-", - "A11900-", - "T11901-", - "T11902-", - "A11903-", - "G11904-", - "T11905-", - "A11906-", - "T11907-", - "A11908-", - "T11909-", - "G11910-", - "T11911-", - "T11912-", - "G11913-", - "G11914-", - "A11915-", - "G11916-", - "G11917-", - "A11918-", - "C11919-", - "A11920-", - "T11921-", - "C11922-", - "C11923-", - "G11924-", - "A11925-", - "G11926-", - "T11927-", - "T11928-", - "C11929-", - "A11930-", - "T11931-", - "T11932-", - "G11933-", - "T11934-", - "T11935-", - "T11936-", - "T11937-", - "C11938-", - "A11939-", - "A11940-", - "T11941-", - "A11942-", - "T11943-", - "C11944-", - "A11945-", - "A11946-", - "A11947-", - "G11948-", - "A11949-", - "G11950-", - "A11951-", - "T11952-", - "G11953-", - "G11954-", - "T11955-", - "T11956-", - "T11957-", - "C11958-", - "C11959-", - "T11960-", - "T11961-", - "A11962-", - "T11963-", - "C11964-", - "A11965-", - "T11966-", - "T11967-", - "T11968-", - "C11969-", - "T11970-", - "C11971-", - "C11972-", - "A11973-", - "T11974-", - "A11975-", - "G11976-", - "T11977-", - "G11978-", - "G11979-", - "T11980-", - "A11981-", - "C11982-", - "A11983-", - "A11984-", - "T11985-", - "A11986-", - "C11987-", - "T11988-", - "A11989-", - "C11990-", - "A11991-", - "C11992-", - "A11993-", - "T11994-", - "T11995-", - "A11996-", - "T11997-", - "T11998-", - "C11999-", - "C12000-", - "G12001-", - "T12002-", - "A12003-", - "C12004-", - "G12005-", - "G12006-", - "C12007-", - "T12008-", - "T12009-", - "T12010-", - "C12011-", - "C12012-", - "A12013-", - "T12014-", - "T12015-", - "C12016-", - "T12017-", - "C12018-", - "C12019-", - "A12020-", - "A12021-", - "A12022-", - "A12023-", - "A12024-", - "C12025-", - "A12026-", - "A12027-", - "T12028-", - "T12029-", - "T12030-", - "T12031-", - "A12032-", - "C12033-", - "C12034-", - "A12035-", - "A12036-", - "A12037-", - "T12038-", - "C12039-", - "T12040-", - "A12041-", - "A12042-", - "A12043-", - "T12044-", - "C12045-", - "T12046-", - "A12047-", - "C12048-", - "A12049-", - "T12050-", - "C12051-", - "T12052-", - "T12053-", - "T12054-", - "A12055-", - "T12056-", - "T12057-", - "G12058-", - "T12059-", - "A12060-", - "T12061-", - "C12062-", - "T12063-", - "A12064-", - "T12065-", - "A12066-", - "A12067-", - "T12068-", - "C12069-", - "A12070-", - "C12071-", - "T12072-", - "A12073-", - "T12074-", - "T12075-", - "T12076-", - "A12077-", - "G12078-", - "A12079-", - "T12080-", - "A12081-", - "A12082-", - "T12083-", - "C12084-", - "A12085-", - "G12086-", - "C12087-", - "C12088-", - "A12089-", - "T12090-", - "A12091-", - "A12092-", - "T12093-", - "T12094-", - "C12095-", - "C12096-", - "T12097-", - "C12098-", - "G12099-", - "A12100-", - "G12101-", - "T12102-", - "G12103-", - "C12104-", - "A12105-", - "A12106-", - "C12107-", - "A12108-", - "T12109-", - "G12110-", - "T12111-", - "T12112-", - "A12113-", - "G12114-", - "A12115-", - "T12116-", - "C12117-", - "G12118-", - "T12119-", - "C12120-", - "T12121-", - "A12122-", - "T12123-", - "A12124-", - "T12125-", - "A12126-", - "T12127-", - "G12128-", - "A12129-", - "A12130-", - "T12131-", - "A12132-", - "A12133-", - "G12134-", - "C12135-", - "C12136-", - "G12137-", - "T12138-", - "G12139-", - "T12140-", - "T12141-", - "A12142-", - "T12143-", - "C12144-", - "T12145-", - "A12146-", - "T12147-", - "T12148-", - "C12149-", - "C12150-", - "T12151-", - "T12152-", - "T12153-", - "C12154-", - "A12155-", - "T12156-", - "T12157-", - "A12158-", - "A12159-", - "C12160-", - "A12161-", - "A12162-", - "T12163-", - "T12164-", - "T12165-", - "A12166-", - "A12167-", - "C12168-", - "G12169-", - "A12170-", - "T12171-", - "G12172-", - "T12173-", - "C12174-", - "T12175-", - "A12176-", - "T12177-", - "A12178-", - "T12179-", - "C12180-", - "T12181-", - "A12182-", - "T12183-", - "A12184-", - "T12185-", - "G12186-", - "A12187-", - "G12188-", - "A12189-", - "T12190-", - "G12191-", - "A12192-", - "C12193-", - "T12194-", - "T12195-", - "A12196-", - "A12197-", - "T12198-", - "A12199-", - "T12200-", - "A12201-", - "A12202-", - "T12203-", - "A12204-", - "T12205-", - "T12206-", - "G12207-", - "A12208-", - "A12209-", - "G12210-", - "A12211-", - "G12212-", - "C12213-", - "T12214-", - "G12215-", - "T12216-", - "A12217-", - "C12218-", - "A12219-", - "A12220-", - "T12221-", - "A12222-", - "G12223-", - "T12224-", - "T12225-", - "T12226-", - "T12227-", - "T12228-", - "A12229-", - "T12230-", - "C12231-", - "T12232-", - "A12233-", - "T12234-", - "A12235-", - "G12236-", - "A12237-", - "A12238-", - "G149818A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G151362A" - ], - "OPG023": [ - "S221X", - "S222-", - "I223-", - "D224-", - "K225-", - "N226-", - "Y227-", - "C228-", - "T229-", - "A230-", - "L231-", - "Q232-", - "Y233-", - "Y234-", - "I235-", - "K236-", - "S237-", - "S238-", - "H239-", - "I240-", - "D241-", - "I242-", - "D243-", - "I244-", - "V245-", - "K246-", - "L247-", - "L248-", - "M249-", - "K250-", - "G251-", - "I252-", - "D253-", - "N254-", - "T255-", - "A256-", - "Y257-", - "S258-", - "Y259-", - "I260-", - "D261-", - "D262-", - "L263-", - "T264-", - "C265-", - "C266-", - "T267-", - "R268-", - "G269-", - "I270-", - "M271-", - "A272-", - "D273-", - "Y274-", - "L275-", - "N276-", - "S277-", - "D278-", - "Y279-", - "R280-", - "Y281-", - "N282-", - "K283-", - "D284-", - "V285-", - "D286-", - "L287-", - "D288-", - "L289-", - "V290-", - "K291-", - "L292-", - "F293-", - "L294-", - "E295-", - "N296-", - "G297-", - "K298-", - "P299-", - "Y300-", - "G301-", - "I302-", - "M303-", - "C304-", - "S305-", - "I306-", - "V307-", - "P308-", - "L309-", - "W310-", - "R311-", - "N312-", - "D313-", - "K314-", - "E315-", - "T316-", - "I317-", - "S318-", - "L319-", - "I320-", - "L321-", - "K322-", - "T323-", - "M324-", - "N325-", - "S326-", - "D327-", - "V328-", - "L329-", - "Q330-", - "H331-", - "I332-", - "L333-", - "I334-", - "E335-", - "Y336-", - "M337-", - "T338-", - "F339-", - "G340-", - "D341-", - "I342-", - "D343-", - "I344-", - "P345-", - "L346-", - "V347-", - "E348-", - "C349-", - "M350-", - "L351-", - "E352-", - "Y353-", - "G354-", - "A355-", - "V356-", - "V357-", - "N358-", - "K359-", - "E360-", - "A361-", - "I362-", - "H363-", - "R364-", - "Y365-", - "F366-", - "R367-", - "N368-", - "I369-", - "N370-", - "I371-", - "D372-", - "S373-", - "Y374-", - "T375-", - "M376-", - "K377-", - "Y378-", - "L379-", - "L380-", - "K381-", - "K382-", - "E383-", - "G384-", - "G385-", - "D386-", - "A387-", - "V388-", - "N389-", - "H390-", - "L391-", - "D392-", - "D393-", - "G394-", - "E395-", - "I396-", - "P397-", - "I398-", - "G399-", - "H400-", - "L401-", - "C402-", - "E403-", - "S404-", - "N405-", - "Y406-", - "G407-", - "C408-", - "Y409-", - "N410-", - "F411-", - "Y412-", - "T413-", - "Y414-", - "T415-", - "Y416-", - "K417-", - "K418-", - "G419-", - "L420-", - "C421-", - "D422-", - "M423-", - "S424-", - "Y425-", - "V426-", - "C427-", - "P428-", - "I429-", - "L430-", - "S431-", - "T432-", - "I433-", - "N434-", - "I435-", - "C436-", - "L437-", - "P438-", - "Y439-", - "L440-", - "K441-", - "D442-", - "I443-", - "N444-", - "M445-", - "I446-", - "D447-", - "K448-", - "R449-", - "G450-", - "E451-", - "T452-", - "L453-", - "L454-", - "H455-", - "K456-", - "A457-", - "V458-", - "R459-", - "Y460-", - "N461-", - "K462-", - "Q463-", - "S464-", - "L465-", - "V466-", - "S467-", - "L468-", - "L469-", - "L470-", - "E471-", - "S472-", - "G473-", - "S474-", - "D475-", - "V476-", - "N477-", - "I478-", - "R479-", - "S480-", - "N481-", - "N482-", - "G483-", - "Y484-", - "T485-", - "C486-", - "I487-", - "T488-", - "I489-", - "A490-", - "I491-", - "N492-", - "E493-", - "S494-", - "R495-", - "N496-", - "I497-", - "E498-", - "L499-", - "L500-", - "K501-", - "M502-", - "L503-", - "L504-", - "C505-", - "H506-", - "K507-", - "P508-", - "T509-", - "L510-", - "D511-", - "C512-", - "V513-", - "I514-", - "D515-", - "S516-", - "L517-", - "S518-", - "E519-", - "V520-", - "S521-", - "N522-", - "I523-", - "V524-", - "D525-", - "*661X" - ], - "OPG176": [ - "D4N" - ] - }, - "labels": { - "aa": "OPG023: S221X, S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-, *661X; OPG176: D4N", - "clade": "B.1.15" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI018", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Stocker,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Stocker,H., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI018" - }, - "strain": { - "value": "ON694335" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A192404-", - "G192405-", - "T192406-", - "C192407-", - "A192408-", - "T192409-", - "A192410-", - "A192411-", - "G192412-", - "T192413-", - "T192414-", - "A192415-", - "G192416-", - "T192417-", - "T192418-", - "A192419-", - "A192420-", - "G192421-", - "T192422-", - "C192423-", - "A192424-", - "T192425-", - "A192426-", - "A192427-", - "G192428-", - "T192429-", - "T192430-", - "A192431-", - "G192432-", - "T192433-", - "T192434-", - "A192435-", - "A196604-" - ] - } - } - }, - { - "name": "Monkeypox/PT0129/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-07-12" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0129/2022" - }, - "strain": { - "value": "OP324453" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594A", - "-595T", - "C18133T", - "-196601A", - "-196602A", - "-196603A", - "A196616T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI352", - "node_attrs": { - "div": 66, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI352" - }, - "strain": { - "value": "OP484673" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C21128T", - "G74187T", - "C151111T" - ], - "OPG037": [ - "E436K" - ], - "OPG094": [ - "Q136H" - ] - }, - "labels": { - "aa": "OPG037: E436K; OPG094: Q136H" - } - } - }, - { - "name": "DC_INS_MPX_0722_L", - "node_attrs": { - "div": 63, - "author": { - "author": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M.", - "value": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-08-23" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "DC_INS_MPX_0722_L" - }, - "strain": { - "value": "OP693654" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI561", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI561" - }, - "strain": { - "value": "OP764619" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000079", - "node_attrs": { - "div": 67, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C8385T", - "-11326A", - "-11327T", - "-11328C", - "-11329T", - "-11330A", - "-11331C", - "-11332G", - "-11333A", - "-11334T", - "-11335A", - "-11336T", - "-11337T", - "-11338A", - "-11339G", - "-11340A", - "-11341T", - "-11342A", - "-11343C", - "-11344T", - "-11345T", - "-11346C", - "-11347A", - "-11348C", - "-11349T", - "-11350C", - "-11351A", - "-11352A", - "-11353T", - "-11354G", - "-11355A", - "-11356A", - "-11357T", - "-11358C", - "-11359A", - "-11360A", - "-11361T", - "-11362C", - "-11363A", - "-11364C", - "-11365A", - "-11366C", - "-11367A", - "-11368A", - "-11369T", - "-11370C", - "-11371T", - "-11372A", - "-11373A", - "-11374T", - "-11375G", - "-11376T", - "-11377A", - "-11378G", - "-11379G", - "-11380T", - "-11381T", - "-11382T", - "-11383A", - "-11384T", - "-11385G", - "-11386A", - "-11387C", - "-11388A", - "-11389T", - "-11390A", - "-11391A", - "-11392T", - "-11393A", - "-11394G", - "-11395C", - "-11396A", - "-11397T", - "-11398T", - "-11399T", - "-11400T", - "-11401C", - "-11402A", - "-11403G", - "-11404C", - "-11405A", - "-11406G", - "-11407T", - "-11408T", - "-11409C", - "-11410A", - "-11411A", - "-11412T", - "-11413G", - "-11414T", - "-11415T", - "-11416T", - "-11417C", - "-11418T", - "-11419A", - "-11420G", - "-11421A", - "-11422T", - "-11423T", - "-11424C", - "-11425G", - "-11426T", - "-11427T", - "-11428G", - "-11429A", - "-11430T", - "-11431G", - "-11432G", - "-11433C", - "-11434A", - "-11435A", - "-11436T", - "-11437G", - "-11438G", - "-11439T", - "-11440T", - "-11441A", - "-11442T", - "-11443A", - "-11444C", - "-11445A", - "-11446T", - "-11447G", - "-11448T", - "-11449A", - "-11450T", - "-11451A", - "-11452T", - "-11453C", - "-11454C", - "-11455G", - "-11456T", - "-11457T", - "-11458A", - "-11459T", - "-11460T", - "-11461T", - "-11462G", - "-11463A", - "-11464T", - "-11465C", - "-11466T", - "-11467A", - "-11468A", - "-11469T", - "-11470G", - "-11471T", - "-11472T", - "-11473G", - "-11474A", - "-11475C", - "-11476A", - "-11477T", - "-11478C", - "-11479T", - "-11480G", - "-11481A", - "-11482A", - "-11483C", - "-11484C", - "-11485G", - "-11486G", - "-11487A", - "-11488T", - "-11489T", - "-11490C", - "-11491T", - "-11492A", - "-11493G", - "-11494C", - "-11495A", - "-11496G", - "-11497T", - "-11498A", - "-11499A", - "-11500A", - "-11501G", - "-11502A", - "-11503T", - "-11504A", - "-11505C", - "-11506T", - "-11507A", - "-11508G", - "-11509A", - "-11510G", - "-11511A", - "-11512T", - "-11513T", - "-11514G", - "-11515T", - "-11516T", - "-11517T", - "-11518A", - "-11519T", - "-11520T", - "-11521A", - "-11522T", - "-11523A", - "-11524T", - "-11525C", - "-11526T", - "-11527A", - "-11528A", - "-11529C", - "-11530A", - "-11531G", - "-11532C", - "-11533C", - "-11534T", - "-11535T", - "-11536G", - "-11537T", - "-11538G", - "-11539A", - "-11540A", - "-11541G", - "-11542A", - "-11543A", - "-11544G", - "-11545T", - "-11546G", - "-11547T", - "-11548T", - "-11549T", - "-11550C", - "-11551T", - "-11552C", - "-11553C", - "-11554T", - "-11555C", - "-11556G", - "-11557T", - "-11558T", - "-11559T", - "-11560G", - "-11561T", - "-11562C", - "-11563A", - "-11564A", - "-11565T", - "-11566C", - "-11567A", - "-11568T", - "-11569G", - "-11570T", - "-11571T", - "-11572A", - "-11573A", - "-11574T", - "-11575G", - "-11576T", - "-11577C", - "-11578T", - "-11579T", - "-11580T", - "-11581A", - "-11582A", - "-11583G", - "-11584A", - "-11585T", - "-11586A", - "-11587A", - "-11588G", - "-11589G", - "-11590T", - "-11591A", - "-11592G", - "-11593A", - "-11594C", - "-11595A", - "-11596A", - "-11597A", - "-11598T", - "-11599G", - "-11600T", - "-11601T", - "-11602T", - "-11603A", - "-11604T", - "-11605A", - "-11606G", - "-11607T", - "-11608A", - "-11609C", - "-11610T", - "-11611A", - "-11612A", - "-11613G", - "-11614A", - "-11615A", - "-11616T", - "-11617T", - "-11618G", - "-11619G", - "-11620G", - "-11621C", - "-11622A", - "-11623A", - "-11624A", - "-11625C", - "-11626A", - "-11627T", - "-11628A", - "-11629A", - "-11630G", - "-11631A", - "-11632C", - "-11633A", - "-11634T", - "-11635G", - "-11636T", - "-11637C", - "-11638A", - "-11639C", - "-11640A", - "-11641A", - "-11642A", - "-11643G", - "-11644A", - "-11645C", - "-11646C", - "-11647C", - "-11648T", - "-11649T", - "-11650T", - "-11651T", - "-11652T", - "-11653G", - "-11654T", - "-11655A", - "-11656T", - "-11657G", - "-11658T", - "-11659A", - "-11660T", - "-11661A", - "-11662A", - "-11663G", - "-11664T", - "-11665G", - "-11666T", - "-11667A", - "-11668G", - "-11669A", - "-11670A", - "-11671A", - "-11672T", - "-11673T", - "-11674A", - "-11675T", - "-11676A", - "-11677A", - "-11678C", - "-11679A", - "-11680T", - "-11681C", - "-11682C", - "-11683A", - "-11684T", - "-11685A", - "-11686G", - "-11687T", - "-11688T", - "-11689G", - "-11690G", - "-11691A", - "-11692T", - "-11693T", - "-11694C", - "-11695A", - "-11696C", - "-11697A", - "-11698T", - "-11699A", - "-11700G", - "-11701G", - "-11702T", - "-11703G", - "-11704T", - "-11705C", - "-11706C", - "-11707A", - "-11708A", - "-11709T", - "-11710C", - "-11711G", - "-11712G", - "-11713G", - "-11714A", - "-11715T", - "-11716C", - "-11717T", - "-11718C", - "-11719T", - "-11720C", - "-11721C", - "-11722A", - "-11723T", - "-11724C", - "-11725A", - "-11726T", - "-11727C", - "-11728G", - "-11729A", - "-11730G", - "-11731A", - "-11732T", - "-11733G", - "-11734A", - "-11735T", - "-11736T", - "-11737G", - "-11738A", - "-11739C", - "-11740G", - "-11741G", - "-11742C", - "-11743A", - "-11744T", - "-11745C", - "-11746T", - "-11747C", - "-11748C", - "-11749C", - "-11750C", - "-11751C", - "-11752T", - "-11753T", - "-11754C", - "-11755C", - "-11756T", - "-11757T", - "-11758T", - "-11759T", - "-11760T", - "-11761T", - "-11762A", - "-11763G", - "-11764T", - "-11765A", - "-11766G", - "-11767A", - "-11768T", - "-11769A", - "-11770T", - "-11771T", - "-11772T", - "-11773C", - "-11774A", - "-11775T", - "-11776C", - "-11777G", - "-11778T", - "-11779G", - "-11780T", - "-11781A", - "-11782A", - "-11783G", - "-11784A", - "-11785A", - "-11786T", - "-11787C", - "-11788A", - "-11789A", - "-11790T", - "-11791A", - "-11792T", - "-11793T", - "-11794A", - "-11795A", - "-11796T", - "-11797A", - "-11798T", - "-11799T", - "-11800T", - "-11801C", - "-11802T", - "-11803A", - "-11804A", - "-11805A", - "-11806G", - "-11807T", - "-11808A", - "-11809T", - "-11810C", - "-11811T", - "-11812G", - "-11813T", - "-11814G", - "-11815T", - "-11816A", - "-11817T", - "-11818A", - "-11819G", - "-11820C", - "-11821C", - "-11822T", - "-11823C", - "-11824T", - "-11825T", - "-11826T", - "-11827A", - "-11828T", - "-11829T", - "-11830T", - "-11831A", - "-11832C", - "-11833C", - "-11834A", - "-11835C", - "-11836A", - "-11837G", - "-11838C", - "-11839T", - "-11840C", - "-11841C", - "-11842A", - "-11843T", - "-11844A", - "-11845T", - "-11846T", - "-11847C", - "-11848C", - "-11849A", - "-11850A", - "-11851C", - "-11852A", - "-11853T", - "-11854G", - "-11855C", - "-11856A", - "-11857T", - "-11858T", - "-11859C", - "-11860C", - "-11861A", - "-11862C", - "-11863T", - "-11864A", - "-11865G", - "-11866A", - "-11867G", - "-11868G", - "-11869G", - "-11870A", - "-11871T", - "-11872A", - "-11873T", - "-11874C", - "-11875G", - "-11876A", - "-11877T", - "-11878A", - "-11879T", - "-11880C", - "-11881G", - "-11882C", - "-11883C", - "-11884G", - "-11885A", - "-11886A", - "-11887T", - "-11888G", - "-11889T", - "-11890C", - "-11891A", - "-11892T", - "-11893A", - "-11894T", - "-11895A", - "-11896C", - "-11897T", - "-11898C", - "-11899A", - "-11900A", - "-11901T", - "-11902T", - "-11903A", - "-11904G", - "-11905T", - "-11906A", - "-11907T", - "-11908A", - "-11909T", - "-11910G", - "-11911T", - "-11912T", - "-11913G", - "-11914G", - "-11915A", - "-11916G", - "-11917G", - "-11918A", - "-11919C", - "-11920A", - "-11921T", - "-11922C", - "-11923C", - "-11924G", - "-11925A", - "-11926G", - "-11927T", - "-11928T", - "-11929C", - "-11930A", - "-11931T", - "-11932T", - "-11933G", - "-11934T", - "-11935T", - "-11936T", - "-11937T", - "-11938C", - "-11939A", - "-11940A", - "-11941T", - "-11942A", - "-11943T", - "-11944C", - "-11945A", - "-11946A", - "-11947A", - "-11948G", - "-11949A", - "-11950G", - "-11951A", - "-11952T", - "-11953G", - "-11954G", - "-11955T", - "-11956T", - "-11957T", - "-11958C", - "-11959C", - "-11960T", - "-11961T", - "-11962A", - "-11963T", - "-11964C", - "-11965A", - "-11966T", - "-11967T", - "-11968T", - "-11969C", - "-11970T", - "-11971C", - "-11972C", - "-11973A", - "-11974T", - "-11975A", - "-11976G", - "-11977T", - "-11978G", - "-11979G", - "-11980T", - "-11981A", - "-11982C", - "-11983A", - "-11984A", - "-11985T", - "-11986A", - "-11987C", - "-11988T", - "-11989A", - "-11990C", - "-11991A", - "-11992C", - "-11993A", - "-11994T", - "-11995T", - "-11996A", - "-11997T", - "-11998T", - "-11999C", - "-12000C", - "-12001G", - "-12002T", - "-12003A", - "-12004C", - "-12005G", - "-12006G", - "-12007C", - "-12008T", - "-12009T", - "-12010T", - "-12011C", - "-12012C", - "-12013A", - "-12014T", - "-12015T", - "-12016C", - "-12017T", - "-12018C", - "-12019C", - "-12020A", - "-12021A", - "-12022A", - "-12023A", - "-12024A", - "-12025C", - "-12026A", - "-12027A", - "-12028T", - "-12029T", - "-12030T", - "-12031T", - "-12032A", - "-12033C", - "-12034C", - "-12035A", - "-12036A", - "-12037A", - "-12038T", - "-12039C", - "-12040T", - "-12041A", - "-12042A", - "-12043A", - "-12044T", - "-12045C", - "-12046T", - "-12047A", - "-12048C", - "-12049A", - "-12050T", - "-12051C", - "-12052T", - "-12053T", - "-12054T", - "-12055A", - "-12056T", - "-12057T", - "-12058G", - "-12059T", - "-12060A", - "-12061T", - "-12062C", - "-12063T", - "-12064A", - "-12065T", - "-12066A", - "-12067A", - "-12068T", - "-12069C", - "-12070A", - "-12071C", - "-12072T", - "-12073A", - "-12074T", - "-12075T", - "-12076T", - "-12077A", - "-12078G", - "-12079A", - "-12080T", - "-12081A", - "-12082A", - "-12083T", - "-12084C", - "-12085A", - "-12086G", - "-12087C", - "-12088C", - "-12089A", - "-12090T", - "-12091A", - "-12092A", - "-12093T", - "-12094T", - "-12095C", - "-12096C", - "-12097T", - "-12098C", - "-12099G", - "-12100A", - "-12101G", - "-12102T", - "-12103G", - "-12104C", - "-12105A", - "-12106A", - "-12107C", - "-12108A", - "-12109T", - "-12110G", - "-12111T", - "-12112T", - "-12113A", - "-12114G", - "-12115A", - "-12116T", - "-12117C", - "-12118G", - "-12119T", - "-12120C", - "-12121T", - "-12122A", - "-12123T", - "-12124A", - "-12125T", - "-12126A", - "-12127T", - "-12128G", - "-12129A", - "-12130A", - "-12131T", - "-12132A", - "-12133A", - "-12134G", - "-12135C", - "-12136C", - "-12137G", - "-12138T", - "-12139G", - "-12140T", - "-12141T", - "-12142A", - "-12143T", - "-12144C", - "-12145T", - "-12146A", - "-12147T", - "-12148T", - "-12149C", - "-12150C", - "-12151T", - "-12152T", - "-12153T", - "-12154C", - "-12155A", - "-12156T", - "-12157T", - "-12158A", - "-12159A", - "-12160C", - "-12161A", - "-12162A", - "-12163T", - "-12164T", - "-12165T", - "-12166A", - "-12167A", - "-12168C", - "-12169G", - "-12170A", - "-12171T", - "-12172G", - "-12173T", - "-12174C", - "-12175T", - "-12176A", - "-12177T", - "-12178A", - "-12179T", - "-12180C", - "-12181T", - "-12182A", - "-12183T", - "-12184A", - "-12185T", - "-12186G", - "-12187A", - "-12188G", - "-12189A", - "-12190T", - "-12191G", - "-12192A", - "-12193C", - "-12194T", - "-12195T", - "-12196A", - "-12197A", - "-12198T", - "-12199A", - "-12200T", - "-12201A", - "-12202A", - "-12203T", - "-12204A", - "-12205T", - "-12206T", - "-12207G", - "-12208A", - "-12209A", - "-12210G", - "-12211A", - "-12212G", - "-12213C", - "-12214T", - "-12215G", - "-12216T", - "-12217A", - "-12218C", - "-12219A", - "-12220A", - "-12221T", - "-12222A", - "-12223G", - "-12224T", - "-12225T", - "-12226T", - "-12227T", - "-12228T", - "-12229A", - "-12230T", - "-12231C", - "-12232T", - "-12233A", - "-12234T", - "-12235A", - "-12236G", - "-12237A", - "-12238A", - "G40242A", - "C40335T", - "G139582A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG023": [ - "X221S", - "-222S", - "-223I", - "-224D", - "-225K", - "-226N", - "-227Y", - "-228C", - "-229T", - "-230A", - "-231L", - "-232Q", - "-233Y", - "-234Y", - "-235I", - "-236K", - "-237S", - "-238S", - "-239H", - "-240I", - "-241D", - "-242I", - "-243D", - "-244I", - "-245V", - "-246K", - "-247L", - "-248L", - "-249M", - "-250K", - "-251G", - "-252I", - "-253D", - "-254N", - "-255T", - "-256A", - "-257Y", - "-258S", - "-259Y", - "-260I", - "-261D", - "-262D", - "-263L", - "-264T", - "-265C", - "-266C", - "-267T", - "-268R", - "-269G", - "-270I", - "-271M", - "-272A", - "-273D", - "-274Y", - "-275L", - "-276N", - "-277S", - "-278D", - "-279Y", - "-280R", - "-281Y", - "-282N", - "-283K", - "-284D", - "-285V", - "-286D", - "-287L", - "-288D", - "-289L", - "-290V", - "-291K", - "-292L", - "-293F", - "-294L", - "-295E", - "-296N", - "-297G", - "-298K", - "-299P", - "-300Y", - "-301G", - "-302I", - "-303M", - "-304C", - "-305S", - "-306I", - "-307V", - "-308P", - "-309L", - "-310W", - "-311R", - "-312N", - "-313D", - "-314K", - "-315E", - "-316T", - "-317I", - "-318S", - "-319L", - "-320I", - "-321L", - "-322K", - "-323T", - "-324M", - "-325N", - "-326S", - "-327D", - "-328V", - "-329L", - "-330Q", - "-331H", - "-332I", - "-333L", - "-334I", - "-335E", - "-336Y", - "-337M", - "-338T", - "-339F", - "-340G", - "-341D", - "-342I", - "-343D", - "-344I", - "-345P", - "-346L", - "-347V", - "-348E", - "-349C", - "-350M", - "-351L", - "-352E", - "-353Y", - "-354G", - "-355A", - "-356V", - "-357V", - "-358N", - "-359K", - "-360E", - "-361A", - "-362I", - "-363H", - "-364R", - "-365Y", - "-366F", - "-367R", - "-368N", - "-369I", - "-370N", - "-371I", - "-372D", - "-373S", - "-374Y", - "-375T", - "-376M", - "-377K", - "-378Y", - "-379L", - "-380L", - "-381K", - "-382K", - "-383E", - "-384G", - "-385G", - "-386D", - "-387A", - "-388V", - "-389N", - "-390H", - "-391L", - "-392D", - "-393D", - "-394G", - "-395E", - "-396I", - "-397P", - "-398I", - "-399G", - "-400H", - "-401L", - "-402C", - "-403E", - "-404S", - "-405N", - "-406Y", - "-407G", - "-408C", - "-409Y", - "-410N", - "-411F", - "-412Y", - "-413T", - "-414Y", - "-415T", - "-416Y", - "-417K", - "-418K", - "-419G", - "-420L", - "-421C", - "-422D", - "-423M", - "-424S", - "-425Y", - "-426V", - "-427C", - "-428P", - "-429I", - "-430L", - "-431S", - "-432T", - "-433I", - "-434N", - "-435I", - "-436C", - "-437L", - "-438P", - "-439Y", - "-440L", - "-441K", - "-442D", - "-443I", - "-444N", - "-445M", - "-446I", - "-447D", - "-448K", - "-449R", - "-450G", - "-451E", - "-452T", - "-453L", - "-454L", - "-455H", - "-456K", - "-457A", - "-458V", - "-459R", - "-460Y", - "-461N", - "-462K", - "-463Q", - "-464S", - "-465L", - "-466V", - "-467S", - "-468L", - "-469L", - "-470L", - "-471E", - "-472S", - "-473G", - "-474S", - "-475D", - "-476V", - "-477N", - "-478I", - "-479R", - "-480S", - "-481N", - "-482N", - "-483G", - "-484Y", - "-485T", - "-486C", - "-487I", - "-488T", - "-489I", - "-490A", - "-491I", - "-492N", - "-493E", - "-494S", - "-495R", - "-496N", - "-497I", - "-498E", - "-499L", - "-500L", - "-501K", - "-502M", - "-503L", - "-504L", - "-505C", - "-506H", - "-507K", - "-508P", - "-509T", - "-510L", - "-511D", - "-512C", - "-513V", - "-514I", - "-515D", - "-516S", - "-517L", - "-518S", - "-519E", - "-520V", - "-521S", - "-522N", - "-523I", - "-524V", - "-525D", - "X661*" - ], - "OPG058": [ - "E34K" - ] - }, - "labels": { - "aa": "OPG023: X221S, -222S, -223I, -224D, -225K, -226N, -227Y, -228C, -229T, -230A, -231L, -232Q, -233Y, -234Y, -235I, -236K, -237S, -238S, -239H, -240I, -241D, -242I, -243D, -244I, -245V, -246K, -247L, -248L, -249M, -250K, -251G, -252I, -253D, -254N, -255T, -256A, -257Y, -258S, -259Y, -260I, -261D, -262D, -263L, -264T, -265C, -266C, -267T, -268R, -269G, -270I, -271M, -272A, -273D, -274Y, -275L, -276N, -277S, -278D, -279Y, -280R, -281Y, -282N, -283K, -284D, -285V, -286D, -287L, -288D, -289L, -290V, -291K, -292L, -293F, -294L, -295E, -296N, -297G, -298K, -299P, -300Y, -301G, -302I, -303M, -304C, -305S, -306I, -307V, -308P, -309L, -310W, -311R, -312N, -313D, -314K, -315E, -316T, -317I, -318S, -319L, -320I, -321L, -322K, -323T, -324M, -325N, -326S, -327D, -328V, -329L, -330Q, -331H, -332I, -333L, -334I, -335E, -336Y, -337M, -338T, -339F, -340G, -341D, -342I, -343D, -344I, -345P, -346L, -347V, -348E, -349C, -350M, -351L, -352E, -353Y, -354G, -355A, -356V, -357V, -358N, -359K, -360E, -361A, -362I, -363H, -364R, -365Y, -366F, -367R, -368N, -369I, -370N, -371I, -372D, -373S, -374Y, -375T, -376M, -377K, -378Y, -379L, -380L, -381K, -382K, -383E, -384G, -385G, -386D, -387A, -388V, -389N, -390H, -391L, -392D, -393D, -394G, -395E, -396I, -397P, -398I, -399G, -400H, -401L, -402C, -403E, -404S, -405N, -406Y, -407G, -408C, -409Y, -410N, -411F, -412Y, -413T, -414Y, -415T, -416Y, -417K, -418K, -419G, -420L, -421C, -422D, -423M, -424S, -425Y, -426V, -427C, -428P, -429I, -430L, -431S, -432T, -433I, -434N, -435I, -436C, -437L, -438P, -439Y, -440L, -441K, -442D, -443I, -444N, -445M, -446I, -447D, -448K, -449R, -450G, -451E, -452T, -453L, -454L, -455H, -456K, -457A, -458V, -459R, -460Y, -461N, -462K, -463Q, -464S, -465L, -466V, -467S, -468L, -469L, -470L, -471E, -472S, -473G, -474S, -475D, -476V, -477N, -478I, -479R, -480S, -481N, -482N, -483G, -484Y, -485T, -486C, -487I, -488T, -489I, -490A, -491I, -492N, -493E, -494S, -495R, -496N, -497I, -498E, -499L, -500L, -501K, -502M, -503L, -504L, -505C, -506H, -507K, -508P, -509T, -510L, -511D, -512C, -513V, -514I, -515D, -516S, -517L, -518S, -519E, -520V, -521S, -522N, -523I, -524V, -525D, X661*; OPG058: E34K" - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-24957C", - "node_attrs": { - "div": 69, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-09-12" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-24957C" - }, - "strain": { - "value": "OP642402" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G125388A", - "G126763A", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ], - "OPG145": [ - "R481H" - ], - "OPG148": [ - "E260K" - ] - }, - "labels": { - "aa": "OPG145: R481H; OPG148: E260K" - } - } - }, - { - "name": "NODE_0000080", - "node_attrs": { - "div": 68, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C127609T" - ] - } - }, - "children": [ - { - "name": "BOL-UNIMOL-MPX-292803-L", - "node_attrs": { - "div": 68, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-08-02" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "BOL-UNIMOL-MPX-292803-L" - }, - "strain": { - "value": "OP390175" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "MET_INS_MPX_0956_C", - "node_attrs": { - "div": 70, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-10-12" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MET_INS_MPX_0956_C" - }, - "strain": { - "value": "OP819950" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G144284A", - "C171808T", - "A196376-", - "T196377-", - "C196378-" - ], - "OPG165": [ - "D257N" - ], - "OPG199": [ - "S274L" - ] - }, - "labels": { - "aa": "OPG165: D257N; OPG199: S274L" - } - } - }, - { - "name": "CES-UNIMOL-MPX-202203848-L", - "node_attrs": { - "div": 68, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-09-14" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "CES-UNIMOL-MPX-202203848-L" - }, - "strain": { - "value": "OP959066" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/UZ_REGA_115", - "node_attrs": { - "div": 70, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-10-28" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_115" - }, - "strain": { - "value": "OR035721" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C21324T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "G180556A", - "T195509-", - "A195510-", - "A195511-" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_163/Belgium/2022", - "node_attrs": { - "div": 73, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-07-27" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_163/Belgium/2022" - }, - "strain": { - "value": "OR086972" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.15" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G31180A", - "C142626T", - "G158549A", - "G159341A", - "C170750T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG163": [ - "S142L" - ], - "OPG185": [ - "G142E" - ], - "OPG198": [ - "A238V" - ] - }, - "labels": { - "aa": "OPG163: S142L; OPG185: G142E; OPG198: A238V" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000081", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G175093A" - ], - "OPG204": [ - "D188N" - ] - }, - "labels": { - "aa": "OPG204: D188N", - "clade": "B.1.13" - } - }, - "children": [ - { - "name": "MPXV-USA-IL-IDPH-002", - "node_attrs": { - "div": 64, - "author": { - "author": "Gagnon,K.T.", - "value": "Gagnon,K.T." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-04" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV-USA-IL-IDPH-002" - }, - "strain": { - "value": "OP536663" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "G119424A", - "G125452A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196601A", - "-196602A", - "-196603A" - ], - "OPG136": [ - "S55L" - ], - "OPG146": [ - "S63L" - ] - }, - "labels": { - "aa": "OPG136: S55L; OPG146: S63L" - } - } - }, - { - "name": "NODE_0000082", - "node_attrs": { - "div": 67, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G22814A", - "G55162A", - "C118921T", - "G137128A", - "G167910A", - "A173274-", - "T173275-", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG038": [ - "H116Y" - ], - "OPG074": [ - "S655L" - ], - "OPG136": [ - "D223N" - ], - "OPG193": [ - "E193K" - ] - }, - "labels": { - "aa": "OPG038: H116Y; OPG074: S655L; OPG136: D223N; OPG193: E193K" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_KS0004", - "node_attrs": { - "div": 67, - "author": { - "author": "Gigante,C., Bradley,A., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Sheth,M.R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Anderson,J., Li,Y.", - "value": "Gigante,C., Bradley,A., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Sheth,M.R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Anderson,J., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-10-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_KS0004" - }, - "strain": { - "value": "OQ320456" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C" - ] - } - } - }, - { - "name": "MPXV_USA_2022_KS0005", - "node_attrs": { - "div": 68, - "author": { - "author": "Gigante,C., Bradley,A., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Anderson,J., Li,Y.", - "value": "Gigante,C., Bradley,A., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Anderson,J., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_KS0005" - }, - "strain": { - "value": "OQ721921" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C110297T", - "A173276-", - "T173277-", - "A179074-", - "T179075-", - "G179076-" - ] - } - } - } - ] - }, - { - "name": "NODE_0000083", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C132520T" - ] - } - }, - "children": [ - { - "name": "MpxV/human/USA/OH-UW-070426/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/OH-UW-070426/2022" - }, - "strain": { - "value": "OP123051" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C162565T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG188": [ - "P324S" - ] - }, - "labels": { - "aa": "OPG188: P324S" - } - } - }, - { - "name": "MPXV_USA_2022_IL0020", - "node_attrs": { - "div": 63, - "author": { - "author": "Gigante,C.M., Ghinai,I., Seabolt,M.H., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Kerins,J., Li,Y.", - "value": "Gigante,C.M., Ghinai,I., Seabolt,M.H., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Kerins,J., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_IL0020" - }, - "strain": { - "value": "OP225962" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-" - ] - } - } - }, - { - "name": "MpxV/human/USA/OH-UW-073812/2022", - "node_attrs": { - "div": 63, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/OH-UW-073812/2022" - }, - "strain": { - "value": "OP257254" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "NODE_0000084", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G165086A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-" - ] - } - }, - "children": [ - { - "name": "MPXV_USA_2022_KY0001", - "node_attrs": { - "div": 66, - "author": { - "author": "Gigante,C.M., Winter,K., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Arora,V., Li,Y.", - "value": "Gigante,C.M., Winter,K., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Arora,V., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_KY0001" - }, - "strain": { - "value": "OP303788" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C43238T", - "G101775A" - ], - "OPG063": [ - "D151N" - ] - }, - "labels": { - "aa": "OPG063: D151N" - } - } - }, - { - "name": "MN-MDH-MPXV_0007", - "node_attrs": { - "div": 65, - "author": { - "author": "Plumb,M.R.", - "value": "Plumb,M.R." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-05" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Minnesota Department of Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MN-MDH-MPXV_0007" - }, - "strain": { - "value": "OP597781" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G127678A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ], - "OPG149": [ - "M161I" - ] - }, - "labels": { - "aa": "OPG149: M161I" - } - } - } - ] - }, - { - "name": "NODE_0000085", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G99832A" - ], - "OPG118": [ - "D463N" - ] - }, - "labels": { - "aa": "OPG118: D463N" - } - }, - "children": [ - { - "name": "MpxV/human/USA/OH-UW-080634/2022", - "node_attrs": { - "div": 67, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/OH-UW-080634/2022" - }, - "strain": { - "value": "OP743957" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C16327T", - "G61713A", - "G135355A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "hMpxV/USA/IL-RIPHL-MPXV-052-0034/2023", - "node_attrs": { - "div": 70, - "author": { - "author": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S.", - "value": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-05-10" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/USA/IL-RIPHL-MPXV-052-0034/2023" - }, - "strain": { - "value": "OR160418" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C27520T", - "G58883A", - "G102186A", - "G129583A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G171410A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "C182950T" - ], - "OPG043": [ - "A146T" - ], - "OPG121": [ - "E133K" - ], - "OPG210": [ - "S532L" - ] - }, - "labels": { - "aa": "OPG043: A146T; OPG121: E133K; OPG210: S532L" - } - } - } - ] - }, - { - "name": "NODE_0000086", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C21383T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G" - ], - "OPG037": [ - "G351S" - ] - }, - "labels": { - "aa": "OPG037: G351S" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/ON/RKI681", - "node_attrs": { - "div": 66, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI681" - }, - "strain": { - "value": "OQ319139" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C24584T", - "G27462A", - "G150550-", - "A152668-", - "T152680-", - "T178896-", - "T178897-", - "A178898-", - "C178899-", - "A178900-", - "A178901-", - "G178902-", - "A178903-", - "T178904-", - "A178905-", - "C178906-", - "A178907-", - "T178908-", - "T178909-", - "T178910-", - "A178911-", - "A178912-", - "T178913-", - "G178914-", - "T178915-", - "G178916-", - "C178917-", - "T178918-", - "T178919-", - "A178920-", - "C178921-", - "G178922-", - "G178923-", - "A178924-", - "A178925-", - "C178926-", - "A178927-", - "T178928-", - "A178929-", - "T178930-", - "A178931-", - "T178932-", - "T178933-", - "T178934-", - "A178935-", - "G178936-", - "A178937-", - "A178938-", - "A178939-", - "C178940-", - "A178941-", - "T178942-", - "C178943-", - "T178944-", - "A178945-", - "C178946-", - "T178947-", - "A178948-", - "A178949-", - "C178950-", - "G178951-", - "A178952-", - "T178953-", - "T178954-", - "T178955-", - "T178956-", - "T178957-", - "T178958-", - "A178959-", - "T178960-", - "G178961-", - "C178962-", - "T178963-", - "T178964-", - "G178965-", - "T178966-", - "A178967-" - ], - "OPG040": [ - "D299N" - ], - "OPG043": [ - "S165L" - ] - }, - "labels": { - "aa": "OPG040: D299N; OPG043: S165L" - } - } - }, - { - "name": "NODE_0000087", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G85431A", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG106": [ - "S23F" - ] - }, - "labels": { - "aa": "OPG106: S23F" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI287", - "node_attrs": { - "div": 66, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Friesen,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Friesen,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI287" - }, - "strain": { - "value": "OP270476" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C172851T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI901", - "node_attrs": { - "div": 67, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI901" - }, - "strain": { - "value": "OQ773520" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.13" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C146446T", - "C147140T" - ], - "OPG170": [ - "M111I" - ] - }, - "labels": { - "aa": "OPG170: M111I" - } - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000088", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G12169A", - "G44960A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - }, - "labels": { - "clade": "B.1.17" - } - }, - "children": [ - { - "name": "hMPX/Human/USA/CA-LACPHL-MA00051/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Hemarajata,P., Green,N.M.", - "value": "Hemarajata,P., Green,N.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-20" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPX/Human/USA/CA-LACPHL-MA00051/2022" - }, - "strain": { - "value": "OP440533" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C60079T" - ], - "OPG080": [ - "R647K" - ] - }, - "labels": { - "aa": "OPG080: R647K" - } - } - }, - { - "name": "hMPX/Human/USA/CA-LACPHL-MA00039/2022", - "node_attrs": { - "div": 63, - "author": { - "author": "Hemarajata,P., Green,N.M.", - "value": "Hemarajata,P., Green,N.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-01" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPX/Human/USA/CA-LACPHL-MA00039/2022" - }, - "strain": { - "value": "OP440562" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "hMPX/Human/USA/CA-LACPHL-MA00085/2022", - "node_attrs": { - "div": 63, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-13" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPX/Human/USA/CA-LACPHL-MA00085/2022" - }, - "strain": { - "value": "OP442552" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G472-", - "A473-", - "T474-", - "A196429-", - "G196430-", - "A196431-" - ] - } - } - }, - { - "name": "hMPX/USA/CA-LACPHL-MA00168/2022", - "node_attrs": { - "div": 63, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-19" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPX/USA/CA-LACPHL-MA00168/2022" - }, - "strain": { - "value": "OP580601" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G520-", - "A521-", - "A522-" - ] - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00334/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-11-09" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00334/2022" - }, - "strain": { - "value": "OP890562" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G39327A", - "T173806-" - ], - "OPG057": [ - "A290V" - ] - }, - "labels": { - "aa": "OPG057: A290V" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00310/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-11-09" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00310/2022" - }, - "strain": { - "value": "OP890567" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C39334G", - "G140635A", - "G164476A" - ], - "OPG057": [ - "A288P" - ], - "OPG160": [ - "S147L" - ], - "OPG189": [ - "E382K" - ] - }, - "labels": { - "aa": "OPG057: A288P; OPG160: S147L; OPG189: E382K" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00439/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-10-09" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00439/2022" - }, - "strain": { - "value": "OQ503835" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G155611A", - "A196429-", - "G196430-", - "A196431-" - ] - } - } - }, - { - "name": "NODE_0000089", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A11836G", - "C113363T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G171959A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179154C", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG132": [ - "D60N" - ] - }, - "labels": { - "aa": "OPG132: D60N" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-083781/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-083781/2022" - }, - "strain": { - "value": "OP392544" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/USA/WA-UW-084166/2022", - "node_attrs": { - "div": 68, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-084166/2022" - }, - "strain": { - "value": "OP628456" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C12850T", - "G69249A" - ] - } - } - } - ] - }, - { - "name": "NODE_0000090", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C177626T" - ] - } - }, - "children": [ - { - "name": "Monkeypox virus/Human/USA/CA-LACPHL-MA00259/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-10-13" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox virus/Human/USA/CA-LACPHL-MA00259/2022" - }, - "strain": { - "value": "OP748945" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T39397C", - "G86148A" - ], - "OPG057": [ - "N267D" - ] - }, - "labels": { - "aa": "OPG057: N267D" - } - } - }, - { - "name": "Monkeypox virus/Human/USA/CA-LACPHL-MA00262/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-21" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox virus/Human/USA/CA-LACPHL-MA00262/2022" - }, - "strain": { - "value": "OP748948" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T528-", - "G529-", - "A530-", - "G165305A" - ], - "OPG190": [ - "E62K" - ] - }, - "labels": { - "aa": "OPG190: E62K" - } - } - } - ] - }, - { - "name": "NODE_0000091", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T39394-", - "A39395-", - "T39396-", - "C85931T" - ], - "OPG057": [ - "N267X", - "R268X", - "*373X" - ] - }, - "labels": { - "aa": "OPG057: N267X, R268X, *373X" - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00423/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-12-02" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00423/2022" - }, - "strain": { - "value": "OQ503816" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000092", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G182189A" - ] - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00426/2022", - "node_attrs": { - "div": 67, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-12-14" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00426/2022" - }, - "strain": { - "value": "OQ503819" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C177509T", - "C177703T" - ], - "OPG205": [ - "S683L" - ] - }, - "labels": { - "aa": "OPG205: S683L" - } - } - }, - { - "name": "NODE_0000093", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G71249A" - ], - "OPG090": [ - "R24Q" - ] - }, - "labels": { - "aa": "OPG090: R24Q" - } - }, - "children": [ - { - "name": "hMpxV/USA/CACDPH1MPX1000178/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-01-10" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/USA/CACDPH1MPX1000178/2022" - }, - "strain": { - "value": "OQ547885" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T6975-" - ] - } - } - }, - { - "name": "OQ991943", - "node_attrs": { - "div": 66, - "author": { - "author": "Kath,C., Haw,M., Espinosa,A., Hacker,J.", - "value": "Kath,C., Haw,M., Espinosa,A., Hacker,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-01-13" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "OQ991943" - }, - "strain": { - "value": "OQ991943" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.17" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000100", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G181367A", - "A196604-" - ] - }, - "labels": { - "clade": "B.1.9" - } - }, - "children": [ - { - "name": "Monkeypox/PT0043/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-05-30" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0043/2022" - }, - "strain": { - "value": "ON843175" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0311/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-06-06" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0311/2022" - }, - "strain": { - "value": "OP414345" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0331/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-05-28" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0331/2022" - }, - "strain": { - "value": "OP414362" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-596T", - "-196603A", - "-196604A" - ] - } - } - }, - { - "name": "Monkeypox/PT0394/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-07-13" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0394/2022" - }, - "strain": { - "value": "OP555490" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-196603A", - "-196604A" - ] - } - } - }, - { - "name": "DC_INS_MPX_0718_L", - "node_attrs": { - "div": 63, - "author": { - "author": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M.", - "value": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-08-16" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "DC_INS_MPX_0718_L" - }, - "strain": { - "value": "OP693652" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-596T", - "G134122T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "NODE_0000101", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C101868T", - "C103427T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG121": [ - "P27S" - ] - }, - "labels": { - "aa": "OPG121: P27S" - } - }, - "children": [ - { - "name": "NY-NYCPHL-000330", - "node_attrs": { - "div": 66, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-08" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000330" - }, - "strain": { - "value": "OQ468869" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G107496A", - "G173727A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T" - ] - } - } - }, - { - "name": "NODE_0000102", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G61329A" - ] - } - }, - "children": [ - { - "name": "MPXV_USA_2022_NJ0005", - "node_attrs": { - "div": 65, - "author": { - "author": "Gigante,C.M., Acheampong,E., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Morrison,S.S., Seabolt,M.H., Weigand,M.R., Knipe,K., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., McDermott,D., Li,Y.", - "value": "Gigante,C.M., Acheampong,E., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Morrison,S.S., Seabolt,M.H., Weigand,M.R., Knipe,K., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., McDermott,D., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_NJ0005" - }, - "strain": { - "value": "OP687938" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NY-NYCPHL-000422", - "node_attrs": { - "div": 66, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-07" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000422" - }, - "strain": { - "value": "OQ419012" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T39394-", - "A39395-", - "T39396-", - "A49374G", - "T50371-", - "C50372-", - "T50373-", - "C50374-", - "T50375-", - "A50376-", - "C50377-", - "C50378-", - "C50379-", - "T50380-", - "A50381-", - "A50382-", - "A50383-", - "C50384-", - "T50385-", - "T50386-", - "T50387-", - "A50388-", - "A50389-", - "C50390-", - "A50391-", - "A50392-", - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T" - ], - "OPG057": [ - "N267X", - "R268X", - "*373X" - ], - "OPG068": [ - "N392D" - ], - "OPG069": [ - "L129X", - "S130-", - "T131-", - "L132-", - "N133-", - "F134-", - "N135-", - "N136X", - "*167X" - ] - }, - "labels": { - "aa": "OPG057: N267X, R268X, *373X; OPG068: N392D; OPG069: L129X, S130-, T131-, L132-, N133-, F134-, N135-, N136X, *167X" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000103", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G176823A" - ], - "OPG205": [ - "E390K" - ] - }, - "labels": { - "aa": "OPG205: E390K" - } - }, - "children": [ - { - "name": "Monkeypox/PT0008/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Ferreira,R., Sobral,D., Nunes,A., Santos,J.D., Mixao,V., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Ferreira,R., Sobral,D., Nunes,A., Santos,J.D., Mixao,V., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-05-15" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0008/2022" - }, - "strain": { - "value": "ON585038" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A11326-", - "T11327-", - "C11328-", - "T11329-", - "A11330-", - "C11331-", - "G11332-", - "A11333-", - "T11334-", - "A11335-", - "T11336-", - "T11337-", - "A11338-", - "G11339-", - "A11340-", - "T11341-", - "A11342-", - "C11343-", - "T11344-", - "T11345-", - "C11346-", - "A11347-", - "C11348-", - "T11349-", - "C11350-", - "A11351-", - "A11352-", - "T11353-", - "G11354-", - "A11355-", - "A11356-", - "T11357-", - "C11358-", - "A11359-", - "A11360-", - "T11361-", - "C11362-", - "A11363-", - "C11364-", - "A11365-", - "C11366-", - "A11367-", - "A11368-", - "T11369-", - "C11370-", - "T11371-", - "A11372-", - "A11373-", - "T11374-", - "G11375-", - "T11376-", - "A11377-", - "G11378-", - "G11379-", - "T11380-", - "T11381-", - "T11382-", - "A11383-", - "T11384-", - "G11385-", - "A11386-", - "C11387-", - "A11388-", - "T11389-", - "A11390-", - "A11391-", - "T11392-", - "A11393-", - "G11394-", - "C11395-", - "A11396-", - "T11397-", - "T11398-", - "T11399-", - "T11400-", - "C11401-", - "A11402-", - "G11403-", - "C11404-", - "A11405-", - "G11406-", - "T11407-", - "T11408-", - "C11409-", - "A11410-", - "A11411-", - "T11412-", - "G11413-", - "T11414-", - "T11415-", - "T11416-", - "C11417-", - "T11418-", - "A11419-", - "G11420-", - "A11421-", - "T11422-", - "T11423-", - "C11424-", - "G11425-", - "T11426-", - "T11427-", - "G11428-", - "A11429-", - "T11430-", - "G11431-", - "G11432-", - "C11433-", - "A11434-", - "A11435-", - "T11436-", - "G11437-", - "G11438-", - "T11439-", - "T11440-", - "A11441-", - "T11442-", - "A11443-", - "C11444-", - "A11445-", - "T11446-", - "G11447-", - "T11448-", - "A11449-", - "T11450-", - "A11451-", - "T11452-", - "C11453-", - "C11454-", - "G11455-", - "T11456-", - "T11457-", - "A11458-", - "T11459-", - "T11460-", - "T11461-", - "G11462-", - "A11463-", - "T11464-", - "C11465-", - "T11466-", - "A11467-", - "A11468-", - "T11469-", - "G11470-", - "T11471-", - "T11472-", - "G11473-", - "A11474-", - "C11475-", - "A11476-", - "T11477-", - "C11478-", - "T11479-", - "G11480-", - "A11481-", - "A11482-", - "C11483-", - "C11484-", - "G11485-", - "G11486-", - "A11487-", - "T11488-", - "T11489-", - "C11490-", - "T11491-", - "A11492-", - "G11493-", - "C11494-", - "A11495-", - "G11496-", - "T11497-", - "A11498-", - "A11499-", - "A11500-", - "G11501-", - "A11502-", - "T11503-", - "A11504-", - "C11505-", - "T11506-", - "A11507-", - "G11508-", - "A11509-", - "G11510-", - "A11511-", - "T11512-", - "T11513-", - "G11514-", - "T11515-", - "T11516-", - "T11517-", - "A11518-", - "T11519-", - "T11520-", - "A11521-", - "T11522-", - "A11523-", - "T11524-", - "C11525-", - "T11526-", - "A11527-", - "A11528-", - "C11529-", - "A11530-", - "G11531-", - "C11532-", - "C11533-", - "T11534-", - "T11535-", - "G11536-", - "T11537-", - "G11538-", - "A11539-", - "A11540-", - "G11541-", - "A11542-", - "A11543-", - "G11544-", - "T11545-", - "G11546-", - "T11547-", - "T11548-", - "T11549-", - "C11550-", - "T11551-", - "C11552-", - "C11553-", - "T11554-", - "C11555-", - "G11556-", - "T11557-", - "T11558-", - "T11559-", - "G11560-", - "T11561-", - "C11562-", - "A11563-", - "A11564-", - "T11565-", - "C11566-", - "A11567-", - "T11568-", - "G11569-", - "T11570-", - "T11571-", - "A11572-", - "A11573-", - "T11574-", - "G11575-", - "T11576-", - "C11577-", - "T11578-", - "T11579-", - "T11580-", - "A11581-", - "A11582-", - "G11583-", - "A11584-", - "T11585-", - "A11586-", - "A11587-", - "G11588-", - "G11589-", - "T11590-", - "A11591-", - "G11592-", - "A11593-", - "C11594-", - "A11595-", - "A11596-", - "A11597-", - "T11598-", - "G11599-", - "T11600-", - "T11601-", - "T11602-", - "A11603-", - "T11604-", - "A11605-", - "G11606-", - "T11607-", - "A11608-", - "C11609-", - "T11610-", - "A11611-", - "A11612-", - "G11613-", - "A11614-", - "A11615-", - "T11616-", - "T11617-", - "G11618-", - "G11619-", - "G11620-", - "C11621-", - "A11622-", - "A11623-", - "A11624-", - "C11625-", - "A11626-", - "T11627-", - "A11628-", - "A11629-", - "G11630-", - "A11631-", - "C11632-", - "A11633-", - "T11634-", - "G11635-", - "T11636-", - "C11637-", - "A11638-", - "C11639-", - "A11640-", - "A11641-", - "A11642-", - "G11643-", - "A11644-", - "C11645-", - "C11646-", - "C11647-", - "T11648-", - "T11649-", - "T11650-", - "T11651-", - "T11652-", - "G11653-", - "T11654-", - "A11655-", - "T11656-", - "G11657-", - "T11658-", - "A11659-", - "T11660-", - "A11661-", - "A11662-", - "G11663-", - "T11664-", - "G11665-", - "T11666-", - "A11667-", - "G11668-", - "A11669-", - "A11670-", - "A11671-", - "T11672-", - "T11673-", - "A11674-", - "T11675-", - "A11676-", - "A11677-", - "C11678-", - "A11679-", - "T11680-", - "C11681-", - "C11682-", - "A11683-", - "T11684-", - "A11685-", - "G11686-", - "T11687-", - "T11688-", - "G11689-", - "G11690-", - "A11691-", - "T11692-", - "T11693-", - "C11694-", - "A11695-", - "C11696-", - "A11697-", - "T11698-", - "A11699-", - "G11700-", - "G11701-", - "T11702-", - "G11703-", - "T11704-", - "C11705-", - "C11706-", - "A11707-", - "A11708-", - "T11709-", - "C11710-", - "G11711-", - "G11712-", - "G11713-", - "A11714-", - "T11715-", - "C11716-", - "T11717-", - "C11718-", - "T11719-", - "C11720-", - "C11721-", - "A11722-", - "T11723-", - "C11724-", - "A11725-", - "T11726-", - "C11727-", - "G11728-", - "A11729-", - "G11730-", - "A11731-", - "T11732-", - "G11733-", - "A11734-", - "T11735-", - "T11736-", - "G11737-", - "A11738-", - "C11739-", - "G11740-", - "G11741-", - "C11742-", - "A11743-", - "T11744-", - "C11745-", - "T11746-", - "C11747-", - "C11748-", - "C11749-", - "C11750-", - "C11751-", - "T11752-", - "T11753-", - "C11754-", - "C11755-", - "T11756-", - "T11757-", - "T11758-", - "T11759-", - "T11760-", - "T11761-", - "A11762-", - "G11763-", - "T11764-", - "A11765-", - "G11766-", - "A11767-", - "T11768-", - "A11769-", - "T11770-", - "T11771-", - "T11772-", - "C11773-", - "A11774-", - "T11775-", - "C11776-", - "G11777-", - "T11778-", - "G11779-", - "T11780-", - "A11781-", - "A11782-", - "G11783-", - "A11784-", - "A11785-", - "T11786-", - "C11787-", - "A11788-", - "A11789-", - "T11790-", - "A11791-", - "T11792-", - "T11793-", - "A11794-", - "A11795-", - "T11796-", - "A11797-", - "T11798-", - "T11799-", - "T11800-", - "C11801-", - "T11802-", - "A11803-", - "A11804-", - "A11805-", - "G11806-", - "T11807-", - "A11808-", - "T11809-", - "C11810-", - "T11811-", - "G11812-", - "T11813-", - "G11814-", - "T11815-", - "A11816-", - "T11817-", - "A11818-", - "G11819-", - "C11820-", - "C11821-", - "T11822-", - "C11823-", - "T11824-", - "T11825-", - "T11826-", - "A11827-", - "T11828-", - "T11829-", - "T11830-", - "A11831-", - "C11832-", - "C11833-", - "A11834-", - "C11835-", - "A11836-", - "G11837-", - "C11838-", - "T11839-", - "C11840-", - "C11841-", - "A11842-", - "T11843-", - "A11844-", - "T11845-", - "T11846-", - "C11847-", - "C11848-", - "A11849-", - "A11850-", - "C11851-", - "A11852-", - "T11853-", - "G11854-", - "C11855-", - "A11856-", - "T11857-", - "T11858-", - "C11859-", - "C11860-", - "A11861-", - "C11862-", - "T11863-", - "A11864-", - "G11865-", - "A11866-", - "G11867-", - "G11868-", - "G11869-", - "A11870-", - "T11871-", - "A11872-", - "T11873-", - "C11874-", - "G11875-", - "A11876-", - "T11877-", - "A11878-", - "T11879-", - "C11880-", - "G11881-", - "C11882-", - "C11883-", - "G11884-", - "A11885-", - "A11886-", - "T11887-", - "G11888-", - "T11889-", - "C11890-", - "A11891-", - "T11892-", - "A11893-", - "T11894-", - "A11895-", - "C11896-", - "T11897-", - "C11898-", - "A11899-", - "A11900-", - "T11901-", - "T11902-", - "A11903-", - "G11904-", - "T11905-", - "A11906-", - "T11907-", - "A11908-", - "T11909-", - "G11910-", - "T11911-", - "T11912-", - "G11913-", - "G11914-", - "A11915-", - "G11916-", - "G11917-", - "A11918-", - "C11919-", - "A11920-", - "T11921-", - "C11922-", - "C11923-", - "G11924-", - "A11925-", - "G11926-", - "T11927-", - "T11928-", - "C11929-", - "A11930-", - "T11931-", - "T11932-", - "G11933-", - "T11934-", - "T11935-", - "T11936-", - "T11937-", - "C11938-", - "A11939-", - "A11940-", - "T11941-", - "A11942-", - "T11943-", - "C11944-", - "A11945-", - "A11946-", - "A11947-", - "G11948-", - "A11949-", - "G11950-", - "A11951-", - "T11952-", - "G11953-", - "G11954-", - "T11955-", - "T11956-", - "T11957-", - "C11958-", - "C11959-", - "T11960-", - "T11961-", - "A11962-", - "T11963-", - "C11964-", - "A11965-", - "T11966-", - "T11967-", - "T11968-", - "C11969-", - "T11970-", - "C11971-", - "C11972-", - "A11973-", - "T11974-", - "A11975-", - "G11976-", - "T11977-", - "G11978-", - "G11979-", - "T11980-", - "A11981-", - "C11982-", - "A11983-", - "A11984-", - "T11985-", - "A11986-", - "C11987-", - "T11988-", - "A11989-", - "C11990-", - "A11991-", - "C11992-", - "A11993-", - "T11994-", - "T11995-", - "A11996-", - "T11997-", - "T11998-", - "C11999-", - "C12000-", - "G12001-", - "T12002-", - "A12003-", - "C12004-", - "G12005-", - "G12006-", - "C12007-", - "T12008-", - "T12009-", - "T12010-", - "C12011-", - "C12012-", - "A12013-", - "T12014-", - "T12015-", - "C12016-", - "T12017-", - "C12018-", - "C12019-", - "A12020-", - "A12021-", - "A12022-", - "A12023-", - "A12024-", - "C12025-", - "A12026-", - "A12027-", - "T12028-", - "T12029-", - "T12030-", - "T12031-", - "A12032-", - "C12033-", - "C12034-", - "A12035-", - "A12036-", - "A12037-", - "T12038-", - "C12039-", - "T12040-", - "A12041-", - "A12042-", - "A12043-", - "T12044-", - "C12045-", - "T12046-", - "A12047-", - "C12048-", - "A12049-", - "T12050-", - "C12051-", - "T12052-", - "T12053-", - "T12054-", - "A12055-", - "T12056-", - "T12057-", - "G12058-", - "T12059-", - "A12060-", - "T12061-", - "C12062-", - "T12063-", - "A12064-", - "T12065-", - "A12066-", - "A12067-", - "T12068-", - "C12069-", - "A12070-", - "C12071-", - "T12072-", - "A12073-", - "T12074-", - "T12075-", - "T12076-", - "A12077-", - "G12078-", - "A12079-", - "T12080-", - "A12081-", - "A12082-", - "T12083-", - "C12084-", - "A12085-", - "G12086-", - "C12087-", - "C12088-", - "A12089-", - "T12090-", - "A12091-", - "A12092-", - "T12093-", - "T12094-", - "C12095-", - "C12096-", - "T12097-", - "C12098-", - "G12099-", - "A12100-", - "G12101-", - "T12102-", - "G12103-", - "C12104-", - "A12105-", - "A12106-", - "C12107-", - "A12108-", - "T12109-", - "G12110-", - "T12111-", - "T12112-", - "A12113-", - "G12114-", - "A12115-", - "T12116-", - "C12117-", - "G12118-", - "T12119-", - "C12120-", - "T12121-", - "A12122-", - "T12123-", - "A12124-", - "T12125-", - "A12126-", - "T12127-", - "G12128-", - "A12129-", - "A12130-", - "T12131-", - "A12132-", - "A12133-", - "G12134-", - "C12135-", - "C12136-", - "G12137-", - "T12138-", - "G12139-", - "T12140-", - "T12141-", - "A12142-", - "T12143-", - "C12144-", - "T12145-", - "A12146-", - "T12147-", - "T12148-", - "C12149-", - "C12150-", - "T12151-", - "T12152-", - "T12153-", - "C12154-", - "A12155-", - "T12156-", - "T12157-", - "A12158-", - "A12159-", - "C12160-", - "A12161-", - "A12162-", - "T12163-", - "T12164-", - "T12165-", - "A12166-", - "A12167-", - "C12168-", - "G12169-", - "A12170-", - "T12171-", - "G12172-", - "T12173-", - "C12174-", - "T12175-", - "A12176-", - "T12177-", - "A12178-", - "T12179-", - "C12180-", - "T12181-", - "A12182-", - "T12183-", - "A12184-", - "T12185-", - "G12186-", - "A12187-", - "G12188-", - "A12189-", - "T12190-", - "G12191-", - "A12192-", - "C12193-", - "T12194-", - "T12195-", - "A12196-", - "A12197-", - "T12198-", - "A12199-", - "T12200-", - "A12201-", - "A12202-", - "T12203-", - "A12204-", - "T12205-", - "T12206-", - "G12207-", - "A12208-", - "A12209-", - "G12210-", - "A12211-", - "G12212-", - "C12213-", - "T12214-", - "G12215-", - "T12216-", - "A12217-", - "C12218-", - "A12219-", - "A12220-", - "T12221-", - "A12222-", - "G12223-", - "T12224-", - "T12225-", - "T12226-", - "T12227-", - "T12228-", - "A12229-", - "T12230-", - "C12231-", - "T12232-", - "A12233-", - "T12234-", - "A12235-", - "G12236-", - "A12237-", - "A12238-", - "C16968T", - "A188349-" - ], - "OPG023": [ - "S221X", - "S222-", - "I223-", - "D224-", - "K225-", - "N226-", - "Y227-", - "C228-", - "T229-", - "A230-", - "L231-", - "Q232-", - "Y233-", - "Y234-", - "I235-", - "K236-", - "S237-", - "S238-", - "H239-", - "I240-", - "D241-", - "I242-", - "D243-", - "I244-", - "V245-", - "K246-", - "L247-", - "L248-", - "M249-", - "K250-", - "G251-", - "I252-", - "D253-", - "N254-", - "T255-", - "A256-", - "Y257-", - "S258-", - "Y259-", - "I260-", - "D261-", - "D262-", - "L263-", - "T264-", - "C265-", - "C266-", - "T267-", - "R268-", - "G269-", - "I270-", - "M271-", - "A272-", - "D273-", - "Y274-", - "L275-", - "N276-", - "S277-", - "D278-", - "Y279-", - "R280-", - "Y281-", - "N282-", - "K283-", - "D284-", - "V285-", - "D286-", - "L287-", - "D288-", - "L289-", - "V290-", - "K291-", - "L292-", - "F293-", - "L294-", - "E295-", - "N296-", - "G297-", - "K298-", - "P299-", - "Y300-", - "G301-", - "I302-", - "M303-", - "C304-", - "S305-", - "I306-", - "V307-", - "P308-", - "L309-", - "W310-", - "R311-", - "N312-", - "D313-", - "K314-", - "E315-", - "T316-", - "I317-", - "S318-", - "L319-", - "I320-", - "L321-", - "K322-", - "T323-", - "M324-", - "N325-", - "S326-", - "D327-", - "V328-", - "L329-", - "Q330-", - "H331-", - "I332-", - "L333-", - "I334-", - "E335-", - "Y336-", - "M337-", - "T338-", - "F339-", - "G340-", - "D341-", - "I342-", - "D343-", - "I344-", - "P345-", - "L346-", - "V347-", - "E348-", - "C349-", - "M350-", - "L351-", - "E352-", - "Y353-", - "G354-", - "A355-", - "V356-", - "V357-", - "N358-", - "K359-", - "E360-", - "A361-", - "I362-", - "H363-", - "R364-", - "Y365-", - "F366-", - "R367-", - "N368-", - "I369-", - "N370-", - "I371-", - "D372-", - "S373-", - "Y374-", - "T375-", - "M376-", - "K377-", - "Y378-", - "L379-", - "L380-", - "K381-", - "K382-", - "E383-", - "G384-", - "G385-", - "D386-", - "A387-", - "V388-", - "N389-", - "H390-", - "L391-", - "D392-", - "D393-", - "G394-", - "E395-", - "I396-", - "P397-", - "I398-", - "G399-", - "H400-", - "L401-", - "C402-", - "E403-", - "S404-", - "N405-", - "Y406-", - "G407-", - "C408-", - "Y409-", - "N410-", - "F411-", - "Y412-", - "T413-", - "Y414-", - "T415-", - "Y416-", - "K417-", - "K418-", - "G419-", - "L420-", - "C421-", - "D422-", - "M423-", - "S424-", - "Y425-", - "V426-", - "C427-", - "P428-", - "I429-", - "L430-", - "S431-", - "T432-", - "I433-", - "N434-", - "I435-", - "C436-", - "L437-", - "P438-", - "Y439-", - "L440-", - "K441-", - "D442-", - "I443-", - "N444-", - "M445-", - "I446-", - "D447-", - "K448-", - "R449-", - "G450-", - "E451-", - "T452-", - "L453-", - "L454-", - "H455-", - "K456-", - "A457-", - "V458-", - "R459-", - "Y460-", - "N461-", - "K462-", - "Q463-", - "S464-", - "L465-", - "V466-", - "S467-", - "L468-", - "L469-", - "L470-", - "E471-", - "S472-", - "G473-", - "S474-", - "D475-", - "V476-", - "N477-", - "I478-", - "R479-", - "S480-", - "N481-", - "N482-", - "G483-", - "Y484-", - "T485-", - "C486-", - "I487-", - "T488-", - "I489-", - "A490-", - "I491-", - "N492-", - "E493-", - "S494-", - "R495-", - "N496-", - "I497-", - "E498-", - "L499-", - "L500-", - "K501-", - "M502-", - "L503-", - "L504-", - "C505-", - "H506-", - "K507-", - "P508-", - "T509-", - "L510-", - "D511-", - "C512-", - "V513-", - "I514-", - "D515-", - "S516-", - "L517-", - "S518-", - "E519-", - "V520-", - "S521-", - "N522-", - "I523-", - "V524-", - "D525-", - "*661X" - ] - }, - "labels": { - "aa": "OPG023: S221X, S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-, *661X" - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3336/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-06-01" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3336/2022" - }, - "strain": { - "value": "ON880538" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C32627T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-" - ] - } - } - }, - { - "name": "NODE_0000104", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-596T", - "C34432T", - "-196604A" - ], - "OPG053": [ - "E87K" - ] - }, - "labels": { - "aa": "OPG053: E87K" - } - }, - "children": [ - { - "name": "NODE_0000105", - "node_attrs": { - "div": 67, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G37974A", - "C47521T", - "G90736A", - "A150557-", - "T150558-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG056": [ - "S354L" - ], - "OPG111": [ - "D158N" - ] - }, - "labels": { - "aa": "OPG056: S354L; OPG111: D158N" - } - }, - "children": [ - { - "name": "NY-NYCPHL-000158", - "node_attrs": { - "div": 68, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-29" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000158" - }, - "strain": { - "value": "OQ419004" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A74149T", - "G150550-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-" - ], - "OPG094": [ - "T124S" - ] - }, - "labels": { - "aa": "OPG094: T124S" - } - } - }, - { - "name": "NODE_0000106", - "node_attrs": { - "div": 68, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G21065A", - "A150563-", - "T150564-", - "G150565-", - "A150566-" - ] - } - }, - "children": [ - { - "name": "NY-NYCPHL-000197", - "node_attrs": { - "div": 68, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-01" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000197" - }, - "strain": { - "value": "OQ468828" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150557A", - "-150558T" - ] - } - } - }, - { - "name": "NY-NYCPHL-001101", - "node_attrs": { - "div": 68, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-05" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-001101" - }, - "strain": { - "value": "OQ469275" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150559-", - "G150560-", - "A150561-", - "T150562-" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000107", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G155157A" - ], - "OPG181": [ - "R249K" - ] - }, - "labels": { - "aa": "OPG181: R249K" - } - }, - "children": [ - { - "name": "Monkeypox/PT0178/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-06-30" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0178/2022" - }, - "strain": { - "value": "OP324493" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594A", - "-595T", - "-196601A", - "-196602A", - "-196603A", - "A196616T" - ] - } - } - }, - { - "name": "Monkeypox/PT0413/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-07-26" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0413/2022" - }, - "strain": { - "value": "OP555506" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0497/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-16" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0497/2022" - }, - "strain": { - "value": "OP555571" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0536/2022", - "node_attrs": { - "div": 67, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-22" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0536/2022" - }, - "strain": { - "value": "OP555607" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.9" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G13563A", - "C68792T", - "A196604-" - ], - "OPG025": [ - "P569S" - ] - }, - "labels": { - "aa": "OPG025: P569S" - } - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000108", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G111029A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - }, - "labels": { - "clade": "B.1.6" - } - }, - "children": [ - { - "name": "LIM-INS-001", - "node_attrs": { - "div": 62, - "author": { - "author": "Silva,I., Jimenez,V., Hurtado,V., Barcena,L.", - "value": "Silva,I., Jimenez,V., Hurtado,V., Barcena,L." - }, - "country": { - "value": "Peru" - }, - "date": { - "value": "2022-06-25" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "LIM-INS-001" - }, - "strain": { - "value": "OP289782" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "-196601A", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "LIM-INS-003", - "node_attrs": { - "div": 62, - "author": { - "author": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Mestanza,O., Lope,P., Nunez,A.", - "value": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Mestanza,O., Lope,P., Nunez,A." - }, - "country": { - "value": "Peru" - }, - "date": { - "value": "2022-06-27" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "LIM-INS-003" - }, - "strain": { - "value": "OP289783" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "LIM-INS-012", - "node_attrs": { - "div": 63, - "author": { - "author": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Lope,P., Arotinco,G.", - "value": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Lope,P., Arotinco,G." - }, - "country": { - "value": "Peru" - }, - "date": { - "value": "2022-07-06" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "LIM-INS-012" - }, - "strain": { - "value": "OP320552" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C96110T" - ], - "OPG117": [ - "S21L" - ] - }, - "labels": { - "aa": "OPG117: S21L" - } - } - }, - { - "name": "LIM-INS-013", - "node_attrs": { - "div": 62, - "author": { - "author": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Lope,P., Arotinco,G.", - "value": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Lope,P., Arotinco,G." - }, - "country": { - "value": "Peru" - }, - "date": { - "value": "2022-07-08" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "LIM-INS-013" - }, - "strain": { - "value": "OP320553" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "LIM-INS-016", - "node_attrs": { - "div": 64, - "author": { - "author": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Lope,P., Arotinco,G.", - "value": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Lope,P., Arotinco,G." - }, - "country": { - "value": "Peru" - }, - "date": { - "value": "2022-07-09" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "LIM-INS-016" - }, - "strain": { - "value": "OP320554" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G25098A", - "A34289G" - ] - } - } - }, - { - "name": "MPX_3U0idu_9000254", - "node_attrs": { - "div": 62, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_3U0idu_9000254" - }, - "strain": { - "value": "OP415224" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-22752-O", - "node_attrs": { - "div": 63, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-08-18" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-22752-O" - }, - "strain": { - "value": "OP431402" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G15814A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "9000387", - "node_attrs": { - "div": 64, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000387" - }, - "strain": { - "value": "OP536765" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G59112A", - "C87978T" - ] - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00408/2023", - "node_attrs": { - "div": 66, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-01-11" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00408/2023" - }, - "strain": { - "value": "OQ503831" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G10945A", - "G39515A", - "C44627T", - "G56276A", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A196604-" - ], - "OPG064": [ - "M424I" - ] - }, - "labels": { - "aa": "OPG064: M424I" - } - } - }, - { - "name": "NODE_0000109", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150364A", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-" - ], - "OPG176": [ - "E186K" - ] - }, - "labels": { - "aa": "OPG176: E186K" - } - }, - "children": [ - { - "name": "CUN_INS_MPX_0951_C", - "node_attrs": { - "div": 63, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-10-14" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "CUN_INS_MPX_0951_C" - }, - "strain": { - "value": "OP819947" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-" - ] - } - } - }, - { - "name": "hMpxV/USA/CA-CDPH-1MPX1000120/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-20" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/USA/CA-CDPH-1MPX1000120/2022" - }, - "strain": { - "value": "OQ348868" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C166930T" - ], - "OPG192": [ - "S67L" - ] - }, - "labels": { - "aa": "OPG192: S67L" - } - } - } - ] - }, - { - "name": "NODE_0000110", - "node_attrs": { - "div": 70, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C14098T", - "C84063T", - "G97749A", - "G142493A", - "G151324A", - "C170573T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "C187332T", - "G188726A", - "A196429-", - "G196430-", - "A196431-" - ], - "OPG163": [ - "D98N" - ], - "OPG198": [ - "S179L" - ] - }, - "labels": { - "aa": "OPG163: D98N; OPG198: S179L" - } - }, - "children": [ - { - "name": "Monkeypox virus/Human/USA/CA-LACPHL-MA00392/2022", - "node_attrs": { - "div": 70, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-12-06" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox virus/Human/USA/CA-LACPHL-MA00392/2022" - }, - "strain": { - "value": "OQ331003" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00422/2022", - "node_attrs": { - "div": 70, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-12-03" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00422/2022" - }, - "strain": { - "value": "OQ503815" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000111", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G132863A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-24725-L", - "node_attrs": { - "div": 65, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-09-08" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-24725-L" - }, - "strain": { - "value": "OP642380" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C7396T", - "C29887T" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-24947E", - "node_attrs": { - "div": 63, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-09-12" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-24947E" - }, - "strain": { - "value": "OP642401" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000112", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G63811A", - "G167862A", - "C170130T", - "-178536T", - "-178537A", - "-178538T", - "-178539A", - "-178540A", - "-178541G", - "-178542C", - "-178543G", - "-178544G", - "-178545T", - "-178546C", - "-178547G", - "-178548T", - "-178549A", - "-178550C", - "-178551C", - "-178552C", - "-178553A", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-" - ], - "OPG193": [ - "D177N" - ] - }, - "labels": { - "aa": "OPG193: D177N" - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-29396O", - "node_attrs": { - "div": 67, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-10-27" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-29396O" - }, - "strain": { - "value": "OQ696077" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A132863G", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-30518C", - "node_attrs": { - "div": 66, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-11-09" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-30518C" - }, - "strain": { - "value": "OQ696099" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.6" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000139", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C18133T", - "G67611A", - "G130231A", - "G159277A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG185": [ - "E121K" - ] - }, - "labels": { - "aa": "OPG185: E121K", - "clade": "B.1.11" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-070499/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-070499/2022" - }, - "strain": { - "value": "OP169336" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-196603A" - ] - } - } - }, - { - "name": "MAG-UNIMOL-MPX-292982-L", - "node_attrs": { - "div": 65, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-08-20" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MAG-UNIMOL-MPX-292982-L" - }, - "strain": { - "value": "OP390178" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI404", - "node_attrs": { - "div": 66, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI404" - }, - "strain": { - "value": "OP524006" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "G182634A", - "-196603A" - ], - "OPG210": [ - "D427N" - ] - }, - "labels": { - "aa": "OPG210: D427N" - } - } - }, - { - "name": "MPXV-USA-IL-IDPH-048", - "node_attrs": { - "div": 66, - "author": { - "author": "Gagnon,K.T.", - "value": "Gagnon,K.T." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-23" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV-USA-IL-IDPH-048" - }, - "strain": { - "value": "OP536709" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "T48717A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-196601A", - "-196602A", - "-196603A" - ], - "OPG068": [ - "L173I" - ] - }, - "labels": { - "aa": "OPG068: L173I" - } - } - }, - { - "name": "MPXV-USA-IL-IDPH-051", - "node_attrs": { - "div": 65, - "author": { - "author": "Gagnon,K.T.", - "value": "Gagnon,K.T." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-24" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV-USA-IL-IDPH-051" - }, - "strain": { - "value": "OP536712" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-196601A", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "MPXV-USA-IL-IDPH-075", - "node_attrs": { - "div": 65, - "author": { - "author": "Gagnon,K.T.", - "value": "Gagnon,K.T." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-01" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV-USA-IL-IDPH-075" - }, - "strain": { - "value": "OP536736" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-196601A", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "Monkeypox/PT0466/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-05" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0466/2022" - }, - "strain": { - "value": "OP555545" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-25510E", - "node_attrs": { - "div": 66, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-09-03" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-25510E" - }, - "strain": { - "value": "OP642421" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C90842T", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ], - "OPG111": [ - "S193F" - ] - }, - "labels": { - "aa": "OPG111: S193F" - } - } - }, - { - "name": "CUN_INS_MPX_0751_C", - "node_attrs": { - "div": 67, - "author": { - "author": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M.", - "value": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-09-10" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "CUN_INS_MPX_0751_C" - }, - "strain": { - "value": "OP693656" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C33832T", - "C42036T" - ], - "OPG052": [ - "R55Q" - ] - }, - "labels": { - "aa": "OPG052: R55Q" - } - } - }, - { - "name": "SAN_INS_MPX_0973_L", - "node_attrs": { - "div": 68, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-10-17" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "SAN_INS_MPX_0973_L" - }, - "strain": { - "value": "OP819960" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T19741-", - "A19742-", - "G19743-", - "G19744-", - "C19745-", - "G19746-", - "G27840A", - "C64404T", - "C96810T", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-" - ], - "OPG034": [ - "T87X", - "P88-", - "K89X", - "*215X" - ], - "OPG043": [ - "S39F" - ], - "OPG083": [ - "D105N" - ] - }, - "labels": { - "aa": "OPG034: T87X, P88-, K89X, *215X; OPG043: S39F; OPG083: D105N" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00344/2022", - "node_attrs": { - "div": 67, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-11-09" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00344/2022" - }, - "strain": { - "value": "OP920682" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G39327A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G177273A", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "-196603A" - ], - "OPG057": [ - "A290V" - ], - "OPG205": [ - "D540N" - ] - }, - "labels": { - "aa": "OPG057: A290V; OPG205: D540N" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-28220C", - "node_attrs": { - "div": 65, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-10-13" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-28220C" - }, - "strain": { - "value": "OQ261700" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NY-NYCPHL-001029", - "node_attrs": { - "div": 66, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-05" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-001029" - }, - "strain": { - "value": "OQ468561" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C172443T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-196603A" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-30087C", - "node_attrs": { - "div": 68, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-11-08" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-30087C" - }, - "strain": { - "value": "OQ696094" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T220-", - "T221-", - "A222-", - "C42840T", - "C55000T", - "G67730A", - "A196376-", - "T196377-", - "C196378-" - ], - "NBT03_gp052": [ - "E48K" - ], - "OPG085": [ - "R268C" - ] - }, - "labels": { - "aa": "NBT03_gp052: E48K; OPG085: R268C" - } - } - }, - { - "name": "MPXV/UZ_REGA_113", - "node_attrs": { - "div": 68, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-10-28" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_113" - }, - "strain": { - "value": "OR035719" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "C142797T", - "C167995T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "G189258A" - ], - "OPG164": [ - "S7L" - ], - "OPG193": [ - "S221F" - ] - }, - "labels": { - "aa": "OPG164: S7L; OPG193: S221F" - } - } - }, - { - "name": "MPXV/UZ_REGA_235/Belgium/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-08-12" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_235/Belgium/2022" - }, - "strain": { - "value": "OR095053" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - }, - { - "name": "NODE_0000140", - "node_attrs": { - "div": 67, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G19458A", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "C185455T" - ], - "OPG034": [ - "S183L" - ], - "OPG210": [ - "S1367L" - ] - }, - "labels": { - "aa": "OPG034: S183L; OPG210: S1367L" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_MO0002", - "node_attrs": { - "div": 69, - "author": { - "author": "Gigante,C., Cleavinger,K., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Burroughs,M.R., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Sinn,M., Li,Y.", - "value": "Gigante,C., Cleavinger,K., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Burroughs,M.R., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Sinn,M., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-10-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_MO0002" - }, - "strain": { - "value": "OQ320458" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G149818A", - "T167929A", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A196604-" - ], - "OPG176": [ - "D4N" - ], - "OPG193": [ - "I199N" - ] - }, - "labels": { - "aa": "OPG176: D4N; OPG193: I199N" - } - } - }, - { - "name": "MPXV_USA_2022_TX0052", - "node_attrs": { - "div": 68, - "author": { - "author": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y.", - "value": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-12-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_TX0052" - }, - "strain": { - "value": "OR209310" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G74374A" - ], - "OPG094": [ - "E199K" - ] - }, - "labels": { - "aa": "OPG094: E199K" - } - } - } - ] - }, - { - "name": "NODE_0000141", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C35308T" - ], - "OPG054": [ - "R230H" - ] - }, - "labels": { - "aa": "OPG054: R230H" - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-29778O", - "node_attrs": { - "div": 69, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-11-03" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-29778O" - }, - "strain": { - "value": "OQ696093" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G17023A", - "G102395A", - "G148319A", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-" - ], - "OPG029": [ - "S16F" - ] - }, - "labels": { - "aa": "OPG029: S16F" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-3668E", - "node_attrs": { - "div": 68, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2023-02-16" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-3668E" - }, - "strain": { - "value": "OQ957072" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G71777A", - "C120979T" - ], - "OPG138": [ - "D52N" - ] - }, - "labels": { - "aa": "OPG138: D52N" - } - } - } - ] - }, - { - "name": "NODE_0000142", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C89777T", - "-196603A" - ], - "OPG110": [ - "P49L" - ] - }, - "labels": { - "aa": "OPG110: P49L" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-081935/2022", - "node_attrs": { - "div": 67, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-081935/2022" - }, - "strain": { - "value": "OP310052" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G105600A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-099493/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-099493/2022" - }, - "strain": { - "value": "OP743983" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/USA/WA-UW-086090/2022", - "node_attrs": { - "div": 68, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-086090/2022" - }, - "strain": { - "value": "OQ503759" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C90213T", - "G168669A" - ], - "OPG195": [ - "R147K" - ] - }, - "labels": { - "aa": "OPG195: R147K" - } - } - }, - { - "name": "NODE_0000143", - "node_attrs": { - "div": 68, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G52594A", - "G176818A" - ], - "OPG205": [ - "R388Q" - ] - }, - "labels": { - "aa": "OPG205: R388Q" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-095695/2022", - "node_attrs": { - "div": 68, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-095695/2022" - }, - "strain": { - "value": "OP715789" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/USA/WA-UW-109000/2022", - "node_attrs": { - "div": 68, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-10-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-109000/2022" - }, - "strain": { - "value": "OP747058" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.11" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T595-", - "A196603-" - ] - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000144", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C89906T", - "G94798A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG110": [ - "S92F" - ], - "OPG115": [ - "E47K" - ] - }, - "labels": { - "aa": "OPG110: S92F; OPG115: E47K", - "clade": "B.1.10" - } - }, - "children": [ - { - "name": "MpxV/Spain/MD-HGUGM-6513479/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Buenestado-Serrano,S., Palomino-Cabrera,R., Penas-Utrilla,D., Rodriguez-Grande,J., Sola Campoy,P., Perez-Lago,L., Rodriguez-Grande,C., Herranz Martin,M., Suarez,J., Catalan,P., Munoz,P., Garcia de Viedma,D.", - "value": "Buenestado-Serrano,S., Palomino-Cabrera,R., Penas-Utrilla,D., Rodriguez-Grande,J., Sola Campoy,P., Perez-Lago,L., Rodriguez-Grande,C., Herranz Martin,M., Suarez,J., Catalan,P., Munoz,P., Garcia de Viedma,D." - }, - "country": { - "value": "Spain" - }, - "date": { - "value": "2022-05-27" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Microbial Genomics, Hospital General Universitario Gregorio Marañón, Madrid, Spain" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/Spain/MD-HGUGM-6513479/2022" - }, - "strain": { - "value": "ON720848" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A322-", - "T596-", - "T597-", - "A1691-", - "T4293-", - "T6583-", - "T6584-", - "T7248-", - "G7723-", - "T8011-", - "A8032-", - "T8494-", - "T9508-", - "A9864-", - "T10497-", - "A10908-", - "T11184-", - "C11751-", - "T11752-", - "C11754T", - "T11756C", - "T12121-", - "A15754-", - "A17083-", - "T18861-", - "A19353-", - "T20660-", - "A21075-", - "T21971-", - "T24677-", - "T25851-", - "T26098-", - "C27001-", - "A27108-", - "C27798-", - "A28524-", - "A28525-", - "T32188-", - "T33409-", - "G35948-", - "T37976-", - "T39127-", - "T39861-", - "T41738-", - "T42989-", - "C43012-", - "G43199-", - "A43442-", - "T44116-", - "T44735-", - "G46761-", - "T48670-", - "A49130-", - "T49830-", - "A51019-", - "A52765-", - "A54964-", - "A55119-", - "T55557-", - "T56035-", - "T57069-", - "A57274-", - "A58644-", - "T61743-", - "A62034-", - "T63624-", - "A64726-", - "A64931-", - "A65531-", - "A65962-", - "T66777-", - "A66839-", - "A67161-", - "C68464-", - "T68479-", - "C68898-", - "G69145-", - "A69739-", - "G69767-", - "A71250-", - "G71358-", - "T75828-", - "A76072-", - "T76079-", - "T76080-", - "A76150-", - "A76151-", - "A76883-", - "A77254-", - "T77800-", - "T78059-", - "A79037-", - "A79177-", - "G79217-", - "C79533T", - "A79782-", - "G80949-", - "C82480-", - "T84843-", - "T88090-", - "T88831-", - "T88939-", - "A89100-", - "T90643-", - "T91125-", - "T91365-", - "A91579-", - "A91698-", - "T94789-", - "A95338-", - "A95573-", - "G95742-", - "G95818-", - "A97348-", - "A97477-", - "A97496-", - "A97695-", - "A98679-", - "T101449-", - "G101515-", - "T102434-", - "T103362-", - "T103363-", - "T104274-", - "T105355-", - "T106591-", - "T108593-", - "A113916-", - "T113946-", - "C114428-", - "T114514-", - "T114751-", - "T115122-", - "G115798-", - "A116008-", - "C116494-", - "T116958-", - "T121116-", - "T121117-", - "G121268-", - "C121544-", - "T124020-", - "T124747-", - "A125249-", - "A126564-", - "T126680-", - "A126711-", - "A127246-", - "A127747-", - "A132020-", - "A132021-", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "T133084-", - "T133085-", - "T133633-", - "T136777-", - "T137881-", - "A143045-", - "A143360-", - "T143474-", - "A144224-", - "T146127-", - "A147994-", - "A149723-", - "A150337-", - "T150532-", - "T150533-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G150577-", - "A150578-", - "T150579-", - "A150580-", - "T150581-", - "G150582-", - "A150583-", - "T150584-", - "G150620-", - "G150621-", - "A150622-", - "T150623-", - "A150624-", - "T150625-", - "G150626-", - "A150627-", - "T150628-", - "A150629-", - "T150859-", - "A151485-", - "A151506-", - "G151544-", - "A152668-", - "T152680-", - "A153355-", - "A153418-", - "A153514-", - "T154859-", - "T155417-", - "C156605-", - "C156606-", - "A157991-", - "T163494-", - "T163592-", - "A163954-", - "A165456-", - "A166737-", - "G167640-", - "A167964-", - "T168120-", - "A170723-", - "T170754-", - "T170897-", - "T170898-", - "T172079-", - "T172661-", - "G179035-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-", - "-179085T", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091T", - "-179092A", - "-179093T", - "-179094T", - "A179546-", - "A179945-", - "T180901-", - "G181049-", - "A181246-", - "C183531-", - "A183777-", - "T187073-", - "A190929-", - "A191010-", - "G191517-", - "A196604-", - "A196605-", - "T196883-", - "T197177-" - ], - "NBT03_gp052": [ - "L8X", - "Y60X", - "*130X" - ], - "NBT03_gp174": [ - "K174X", - "*177X" - ], - "NBT03_gp175": [ - "R155X", - "*438X" - ], - "OPG019": [ - "E48X", - "*143X" - ], - "OPG021": [ - "Q93X", - "*243X" - ], - "OPG022": [ - "K121X", - "*127X" - ], - "OPG023": [ - "I260X", - "K382R", - "E383X", - "G384X", - "I573X", - "*661X" - ], - "OPG036": [ - "K135X", - "*178X" - ], - "OPG037": [ - "I155X", - "*443X" - ], - "OPG040": [ - "M268X", - "*376X" - ], - "OPG042": [ - "E33X", - "T334X", - "K416X", - "*425X" - ], - "OPG043": [ - "G53X", - "*277X" - ], - "OPG044": [ - "E145X", - "*150X" - ], - "OPG054": [ - "H17X", - "*440X" - ], - "OPG056": [ - "K353X", - "*636X" - ], - "OPG057": [ - "N112X", - "I357X", - "*373X" - ], - "OPG061": [ - "K49X", - "*232X" - ], - "OPG063": [ - "S83X", - "L164X", - "G226X", - "I234X", - "*480X" - ], - "OPG064": [ - "K388X", - "I595X", - "*738X" - ], - "OPG066": [ - "P223X", - "*260X" - ], - "OPG068": [ - "I157X", - "A310X", - "L544X", - "*568X" - ], - "OPG070": [ - "K144X", - "*274X" - ], - "OPG071": [ - "C558X", - "*1007X" - ], - "OPG074": [ - "K19X", - "N364X", - "K523X", - "*666X" - ], - "OPG075": [ - "F75X", - "*109X" - ], - "OPG078": [ - "F56X", - "*74X" - ], - "OPG080": [ - "K92X", - "*772X" - ], - "OPG083": [ - "M365X", - "*424X" - ], - "OPG084": [ - "E2X", - "G70X", - "P270X", - "E414X", - "*677X" - ], - "OPG085": [ - "K18X", - "G23X", - "F457X", - "S565X", - "K585X", - "*592X" - ], - "OPG087": [ - "F14X", - "G97X", - "*221X" - ], - "OPG088": [ - "L33X", - "L42X", - "*125X" - ], - "OPG090": [ - "R24X", - "L60X", - "*64X" - ], - "OPG096": [ - "I81X", - "*93X" - ], - "OPG097": [ - "F242X", - "K266X", - "A268X", - "*345X" - ], - "OPG098": [ - "K119X", - "*252X" - ], - "OPG099": [ - "F46X", - "*129X" - ], - "OPG100": [ - "F18X", - "*153X" - ], - "OPG102": [ - "A31X", - "G45X", - "T150I", - "E233X", - "*334X" - ], - "OPG104": [ - "P24X", - "*134X" - ], - "OPG105": [ - "A452X", - "F1240X", - "*1287X" - ], - "OPG109": [ - "F116X", - "N170X", - "K206X", - "K453X", - "*796X" - ], - "OPG111": [ - "F127X", - "N287X", - "*315X" - ], - "OPG112": [ - "I40X", - "I111X", - "*147X" - ], - "OPG115": [ - "F44X", - "K227X", - "*234X" - ], - "OPG116": [ - "P71X", - "G128X", - "S153X", - "*219X" - ], - "OPG117": [ - "K434X", - "K477X", - "E483X", - "L549X", - "*786X" - ], - "OPG118": [ - "L78X", - "*638X" - ], - "OPG120": [ - "S78X", - "K100X", - "*305X" - ], - "OPG122": [ - "F3X", - "*249X" - ], - "OPG123": [ - "K266X", - "N570X", - "*632X" - ], - "OPG124": [ - "N205X", - "*288X" - ], - "OPG125": [ - "N355X", - "*552X" - ], - "OPG127": [ - "N78X", - "*225X" - ], - "OPG133": [ - "K192X", - "I316X", - "I395X", - "G423X", - "K584X", - "F594X", - "*711X" - ], - "OPG134": [ - "G17X", - "K87X", - "P249X", - "*293X" - ], - "OPG136": [ - "N877X", - "*892X" - ], - "OPG138": [ - "N6X", - "*191X" - ], - "OPG139": [ - "P34X", - "*71X" - ], - "OPG140": [ - "G68X", - "*91X" - ], - "OPG145": [ - "L25X", - "S267X", - "K435X", - "*493X" - ], - "OPG148": [ - "P193X", - "I232X", - "G242X", - "K421X", - "*427X" - ], - "OPG149": [ - "S17X", - "I184X", - "*188X" - ], - "OPG151": [ - "K1033X", - "*1165X" - ], - "OPG153": [ - "K297X", - "*510X" - ], - "OPG154": [ - "K57X", - "*111X" - ], - "OPG164": [ - "R90X", - "S195X", - "*229X" - ], - "OPG165": [ - "K237X", - "*269X" - ], - "OPG170": [ - "I218X", - "*222X" - ], - "OPG172": [ - "K190X", - "*197X" - ], - "OPG175": [ - "S94X", - "*126X" - ], - "OPG176": [ - "K177X", - "*241X" - ], - "OPG178": [ - "L12X", - "*205X" - ], - "OPG180": [ - "K222X", - "K243X", - "K275X", - "*560X" - ], - "OPG181": [ - "F150X", - "*335X" - ], - "OPG189": [ - "D54X", - "I87X", - "K208X", - "*562X" - ], - "OPG190": [ - "E112X", - "*318X" - ], - "OPG192": [ - "K3X", - "*183X" - ], - "OPG193": [ - "G103X", - "K211X", - "F263X", - "*268X" - ], - "OPG198": [ - "Q229X", - "T239X", - "*283X" - ], - "OPG208": [ - "Q94X", - "E227X", - "*358X" - ], - "OPG209": [ - "T128X", - "G178X", - "*191X" - ], - "OPG210": [ - "P726X", - "K808X", - "*1881X" - ] - }, - "labels": { - "aa": "NBT03_gp052: L8X, Y60X, *130X; NBT03_gp174: K174X, *177X; NBT03_gp175: R155X, *438X; OPG019: E48X, *143X; OPG021: Q93X, *243X; OPG022: K121X, *127X; OPG023: I260X, K382R, E383X, G384X, I573X, *661X; OPG036: K135X, *178X; OPG037: I155X, *443X; OPG040: M268X, *376X; OPG042: E33X, T334X, K416X, *425X; OPG043: G53X, *277X; OPG044: E145X, *150X; OPG054: H17X, *440X; OPG056: K353X, *636X; OPG057: N112X, I357X, *373X; OPG061: K49X, *232X; OPG063: S83X, L164X, G226X, I234X, *480X; OPG064: K388X, I595X, *738X; OPG066: P223X, *260X; OPG068: I157X, A310X, L544X, *568X; OPG070: K144X, *274X; OPG071: C558X, *1007X; OPG074: K19X, N364X, K523X, *666X; OPG075: F75X, *109X; OPG078: F56X, *74X; OPG080: K92X, *772X; OPG083: M365X, *424X; OPG084: E2X, G70X, P270X, E414X, *677X; OPG085: K18X, G23X, F457X, S565X, K585X, *592X; OPG087: F14X, G97X, *221X; OPG088: L33X, L42X, *125X; OPG090: R24X, L60X, *64X; OPG096: I81X, *93X; OPG097: F242X, K266X, A268X, *345X; OPG098: K119X, *252X; OPG099: F46X, *129X; OPG100: F18X, *153X; OPG102: A31X, G45X, T150I, E233X, *334X; OPG104: P24X, *134X; OPG105: A452X, F1240X, *1287X; OPG109: F116X, N170X, K206X, K453X, *796X; OPG111: F127X, N287X, *315X; OPG112: I40X, I111X, *147X; OPG115: F44X, K227X, *234X; OPG116: P71X, G128X, S153X, *219X; OPG117: K434X, K477X, E483X, L549X, *786X; OPG118: L78X, *638X; OPG120: S78X, K100X, *305X; OPG122: F3X, *249X; OPG123: K266X, N570X, *632X; OPG124: N205X, *288X; OPG125: N355X, *552X; OPG127: N78X, *225X; OPG133: K192X, I316X, I395X, G423X, K584X, F594X, *711X; OPG134: G17X, K87X, P249X, *293X; OPG136: N877X, *892X; OPG138: N6X, *191X; OPG139: P34X, *71X; OPG140: G68X, *91X; OPG145: L25X, S267X, K435X, *493X; OPG148: P193X, I232X, G242X, K421X, *427X; OPG149: S17X, I184X, *188X; OPG151: K1033X, *1165X; OPG153: K297X, *510X; OPG154: K57X, *111X; OPG164: R90X, S195X, *229X; OPG165: K237X, *269X; OPG170: I218X, *222X; OPG172: K190X, *197X; OPG175: S94X, *126X; OPG176: K177X, *241X; OPG178: L12X, *205X; OPG180: K222X, K243X, K275X, *560X; OPG181: F150X, *335X; OPG189: D54X, I87X, K208X, *562X; OPG190: E112X, *318X; OPG192: K3X, *183X; OPG193: G103X, K211X, F263X, *268X; OPG198: Q229X, T239X, *283X; OPG208: Q94X, E227X, *358X; OPG209: T128X, G178X, *191X; OPG210: P726X, K808X, *1881X" - } - } - }, - { - "name": "MPXV_UK_2022_9000103", - "node_attrs": { - "div": 63, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-06-13" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000103" - }, - "strain": { - "value": "OP205091" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV_UK_2022_9000147", - "node_attrs": { - "div": 63, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-06-14" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000147" - }, - "strain": { - "value": "OP205110" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPX/PT0081/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-07-23" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX/PT0081/2022" - }, - "strain": { - "value": "OP245334" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A590-", - "T591-", - "C120237T", - "G126047A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A196599-", - "C196600-", - "-196601A", - "-196603A" - ], - "OPG148": [ - "R21K" - ] - }, - "labels": { - "aa": "OPG148: R21K" - } - } - }, - { - "name": "NY-NYCPHL-000145", - "node_attrs": { - "div": 64, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-27" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000145" - }, - "strain": { - "value": "OQ504404" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C15311T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - }, - { - "name": "MPXV/Spain/HUNSC_ITER_0005b/2022", - "node_attrs": { - "div": 76, - "author": { - "author": "Munoz-Barrera,A., Ciuffreda,L., Alcoba-Florez,J., Rubio-Rodriguez,L.A., Rodriguez-Perez,H., Gil-Campesino,H., Garcia-Martinez de Artola,D., Salas-Hernandez,J., Rodriguez-Nunez,J., Inigo-Campos,A., Garcia-Olivares,V., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C.", - "value": "Munoz-Barrera,A., Ciuffreda,L., Alcoba-Florez,J., Rubio-Rodriguez,L.A., Rodriguez-Perez,H., Gil-Campesino,H., Garcia-Martinez de Artola,D., Salas-Hernandez,J., Rodriguez-Nunez,J., Inigo-Campos,A., Garcia-Olivares,V., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C." - }, - "country": { - "value": "Spain" - }, - "date": { - "value": "2022-07-01" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Spain/HUNSC_ITER_0005b/2022" - }, - "strain": { - "value": "OQ581847" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A43453G", - "A66769C", - "T88735A", - "G90070A", - "C101656T", - "G104325A", - "C121681T", - "G127869A", - "G132490A", - "T133095A", - "-133168C", - "-133169T", - "-133170T", - "-133171T", - "-133173T", - "T139779C", - "G140866T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C151204T", - "T176743A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG063": [ - "L79P" - ], - "OPG085": [ - "V588G" - ], - "OPG109": [ - "E238V" - ], - "OPG110": [ - "D147N" - ], - "OPG123": [ - "A249V" - ], - "OPG150": [ - "G31R" - ], - "OPG160": [ - "S70Y" - ], - "OPG205": [ - "L363*" - ] - }, - "labels": { - "aa": "OPG063: L79P; OPG085: V588G; OPG109: E238V; OPG110: D147N; OPG123: A249V; OPG150: G31R; OPG160: S70Y; OPG205: L363*" - } - } - }, - { - "name": "NODE_0000145", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C33103T", - "C45605T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ], - "OPG049": [ - "E17K" - ] - }, - "labels": { - "aa": "OPG049: E17K" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI241", - "node_attrs": { - "div": 66, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI241" - }, - "strain": { - "value": "OP215226" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G47702A" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI429", - "node_attrs": { - "div": 65, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI429" - }, - "strain": { - "value": "OP594193" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI885", - "node_attrs": { - "div": 65, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI885" - }, - "strain": { - "value": "OQ773504" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A41660-", - "A41661-", - "T41662-", - "T41663-", - "T41664-", - "G41665-", - "T41666-", - "T41667-", - "T41668-", - "T41669-", - "A41670-", - "C41671-", - "T41672-", - "C41673-", - "T41674-", - "A41675-", - "T41676-", - "A41677-", - "G150550-" - ], - "OPG061": [ - "Y70-", - "R71-", - "V72-", - "K73-", - "Q74-", - "I75-" - ] - }, - "labels": { - "aa": "OPG061: Y70-, R71-, V72-, K73-, Q74-, I75-" - } - } - } - ] - }, - { - "name": "NODE_0000146", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C150831T" - ] - } - }, - "children": [ - { - "name": "MPX-96/Finland/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Kant,R., Smura,T., Vauhkonen,H., Vapalahti,O.", - "value": "Kant,R., Smura,T., Vauhkonen,H., Vapalahti,O." - }, - "country": { - "value": "Finland" - }, - "date": { - "value": "2022-06-16" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Helsinki, Department of Virology, Faculty of Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX-96/Finland/2022" - }, - "strain": { - "value": "ON959143" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "C188491T" - ] - } - } - }, - { - "name": "hMPXV-IHU00012", - "node_attrs": { - "div": 65, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "country": { - "value": "France" - }, - "date": { - "value": "2022-07-19" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPXV-IHU00012" - }, - "strain": { - "value": "OP382489" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G109437A", - "A136513-", - "T136514-", - "C136515-", - "A136516-", - "T136517-", - "C136518-", - "G150568-", - "A150569-", - "T150570-", - "A150571-", - "T150572-", - "G150573-", - "A150574-", - "T150575-", - "G150576-", - "G150577-", - "A150578-", - "T150579-", - "A150580-", - "T150581-", - "G150582-", - "A150583-", - "T150584-", - "G150585-", - "A150586-", - "T150587-", - "A150588-", - "T150589-", - "G150590-", - "A150591-", - "T150592-", - "G150593-" - ], - "OPG129": [ - "S523L" - ], - "OPG153": [ - "D384-", - "D385-" - ] - }, - "labels": { - "aa": "OPG129: S523L; OPG153: D384-, D385-" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI606", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI606" - }, - "strain": { - "value": "OP863256" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "G181049-" - ], - "OPG209": [ - "G178X", - "*191X" - ] - }, - "labels": { - "aa": "OPG209: G178X, *191X" - } - } - }, - { - "name": "NY-NYCPHL-000141", - "node_attrs": { - "div": 64, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-25" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000141" - }, - "strain": { - "value": "OQ469148" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - } - ] - }, - { - "name": "NODE_0000147", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T495C", - "C20879T", - "C60094T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "A196715G" - ], - "OPG036": [ - "M62I" - ], - "OPG080": [ - "R642K" - ] - }, - "labels": { - "aa": "OPG036: M62I; OPG080: R642K" - } - }, - "children": [ - { - "name": "MPX_Tga3e9_9000325", - "node_attrs": { - "div": 66, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_Tga3e9_9000325" - }, - "strain": { - "value": "OP415264" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C495T", - "G86904A", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "G196715A" - ] - } - } - }, - { - "name": "NY-NYCPHL-000734", - "node_attrs": { - "div": 75, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-19" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000734" - }, - "strain": { - "value": "OQ419071" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A57566T", - "T57573-", - "T73740A", - "A74149T", - "T133529G", - "G133535A", - "T134553C", - "T136752C", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150565G", - "-150566A", - "-150567T", - "T156800G", - "G156802T", - "T177464G" - ], - "OPG076": [ - "S20X", - "L22Q", - "*36X" - ], - "OPG093": [ - "F255I" - ], - "OPG094": [ - "T124S" - ], - "OPG153": [ - "K306E" - ], - "OPG205": [ - "I603M" - ] - }, - "labels": { - "aa": "OPG076: S20X, L22Q, *36X; OPG093: F255I; OPG094: T124S; OPG153: K306E; OPG205: I603M" - } - } - }, - { - "name": "NY-NYCPHL-000716", - "node_attrs": { - "div": 65, - "author": { - "author": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-19" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000716" - }, - "strain": { - "value": "OQ468635" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "NY-NYCPHL-000421", - "node_attrs": { - "div": 67, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-01" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000421" - }, - "strain": { - "value": "OQ468985" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C156348T", - "A182480G" - ] - } - } - } - ] - }, - { - "name": "NODE_0000148", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G50672A" - ], - "OPG070": [ - "R28K" - ] - }, - "labels": { - "aa": "OPG070: R28K" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/ON/RKI511", - "node_attrs": { - "div": 66, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-10-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI511" - }, - "strain": { - "value": "OP689664" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C13624T", - "C43472T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ], - "OPG063": [ - "E73K" - ] - }, - "labels": { - "aa": "OPG063: E73K" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-28305C", - "node_attrs": { - "div": 66, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-10-13" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-28305C" - }, - "strain": { - "value": "OQ261705" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C159779T", - "C187683T", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG185": [ - "S288L" - ] - }, - "labels": { - "aa": "OPG185: S288L" - } - } - }, - { - "name": "NODE_0000149", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G45416A", - "C123118T" - ] - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-25431E", - "node_attrs": { - "div": 66, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-09-13" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-25431E" - }, - "strain": { - "value": "OP642417" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-28299E", - "node_attrs": { - "div": 68, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-10-13" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-28299E" - }, - "strain": { - "value": "OQ261704" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G32863A", - "G161575A", - "T195509-", - "A195510-", - "A195511-" - ] - } - } - } - ] - }, - { - "name": "NODE_0000150", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C25087T", - "C62649T" - ], - "OPG040": [ - "R131K" - ] - }, - "labels": { - "aa": "OPG040: R131K" - } - }, - "children": [ - { - "name": "LBMB-UTP_MP-011_VAC", - "node_attrs": { - "div": 66, - "author": { - "author": "Orjuela,M., Tabares,F.A., Anacona,J.D., Lopez,P.A., Zuluaga-Velez,A., Sepulveda-Arias,J.C.", - "value": "Orjuela,M., Tabares,F.A., Anacona,J.D., Lopez,P.A., Zuluaga-Velez,A., Sepulveda-Arias,J.C." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-09-11" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "LBMB-UTP_MP-011_VAC" - }, - "strain": { - "value": "OQ148471" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "LBMB-UTP_MP-019_VAC", - "node_attrs": { - "div": 66, - "author": { - "author": "Tabares,F.A., Anacona,J.D., Lopez,P.A., Orjuela,M., Zuluaga-Velez,A., Sepulveda-Arias,J.C.", - "value": "Tabares,F.A., Anacona,J.D., Lopez,P.A., Orjuela,M., Zuluaga-Velez,A., Sepulveda-Arias,J.C." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-11-11" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "LBMB-UTP_MP-019_VAC" - }, - "strain": { - "value": "OQ148472" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000151", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C49265T" - ] - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-23655-L", - "node_attrs": { - "div": 65, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-08-30" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-23655-L" - }, - "strain": { - "value": "OP459218" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "9000385", - "node_attrs": { - "div": 66, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000385" - }, - "strain": { - "value": "OP536764" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C100007T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "A196604-" - ], - "OPG118": [ - "S521F" - ] - }, - "labels": { - "aa": "OPG118: S521F" - } - } - }, - { - "name": "ANT_INS_MPX_0024_L", - "node_attrs": { - "div": 66, - "author": { - "author": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M.", - "value": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-08-07" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT_INS_MPX_0024_L" - }, - "strain": { - "value": "OP693650" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G93624A" - ], - "OPG113": [ - "E632K" - ] - }, - "labels": { - "aa": "OPG113: E632K" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-31875C", - "node_attrs": { - "div": 69, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-11-24" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-31875C" - }, - "strain": { - "value": "OQ696105" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.10" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A208-", - "G209-", - "A210-", - "C6819T", - "G33823A", - "G38820A", - "C158040T" - ], - "OPG052": [ - "S58L" - ], - "OPG056": [ - "S72L" - ] - }, - "labels": { - "aa": "OPG052: S58L; OPG056: S72L" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000152", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G34308A" - ], - "OPG053": [ - "S128L" - ] - }, - "labels": { - "aa": "OPG053: S128L", - "clade": "B.1.4" - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-2833/2022", - "node_attrs": { - "div": 63, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-05-13" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-2833/2022" - }, - "strain": { - "value": "ON880519" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T85846C" - ], - "OPG107": [ - "M112T" - ] - }, - "labels": { - "aa": "OPG107: M112T" - } - } - }, - { - "name": "MPXV_USA_2022_CO0003", - "node_attrs": { - "div": 65, - "author": { - "author": "Gigante,C.M., Steidley,B., Seabolt,M.H., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Davizon,E.S., Li,Y.", - "value": "Gigante,C.M., Steidley,B., Seabolt,M.H., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Davizon,E.S., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_CO0003" - }, - "strain": { - "value": "OP185714" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C18027T", - "T159165C", - "G162156A", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG031": [ - "D268N" - ] - }, - "labels": { - "aa": "OPG031: D268N" - } - } - }, - { - "name": "ATL-UNIMOL-MPX-292896-L", - "node_attrs": { - "div": 63, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-08-13" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ATL-UNIMOL-MPX-292896-L" - }, - "strain": { - "value": "OP390177" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C176447T", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "NODE_0000153", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C10672T", - "G112481A", - "G163626A" - ], - "OPG022": [ - "E63K" - ] - }, - "labels": { - "aa": "OPG022: E63K" - } - }, - "children": [ - { - "name": "HRYC_MPXV002", - "node_attrs": { - "div": 69, - "author": { - "author": "Ponce-Alonso,M., Martinez-Garcia,L., Olavarrieta,L., Galan,J.C.", - "value": "Ponce-Alonso,M., Martinez-Garcia,L., Olavarrieta,L., Galan,J.C." - }, - "country": { - "value": "Spain" - }, - "date": { - "value": "2023-03-23" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Hospital Ramon y Cajal, Microbiology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "HRYC_MPXV002" - }, - "strain": { - "value": "OR126132" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6376A", - "G11924A", - "G21674A", - "A87705G", - "A179074-", - "T179075-", - "G179076-", - "-179092A", - "-179093T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "C190834T" - ], - "NBT03_gp174": [ - "S142L" - ], - "OPG023": [ - "S326L" - ], - "OPG037": [ - "L254F" - ] - }, - "labels": { - "aa": "NBT03_gp174: S142L; OPG023: S326L; OPG037: L254F" - } - } - }, - { - "name": "NODE_0000154", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G144478A" - ] - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-3214/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-05-30" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3214/2022" - }, - "strain": { - "value": "ON880511" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3393/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Marchand-Austin,A., Eshaghi,A., Patel,S.N., Hasso,M., Gubbay,J.B., Olsha,R.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Marchand-Austin,A., Eshaghi,A., Patel,S.N., Hasso,M., Gubbay,J.B., Olsha,R." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-06-03" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3393/2022" - }, - "strain": { - "value": "ON983160" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/CAN/UN-NML-4152/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Griffiths,E., Jolly,G., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Griffiths,E., Jolly,G., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-07-04" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-4152/2022" - }, - "strain": { - "value": "OP279047" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T" - ] - } - } - }, - { - "name": "MPXV22/human/USA-OK-134", - "node_attrs": { - "div": 68, - "author": { - "author": "Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., O'Dell,J.X., Mannell,M., Wiley,M.R., Cross,S.T.", - "value": "Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., O'Dell,J.X., Mannell,M., Wiley,M.R., Cross,S.T." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-08" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV22/human/USA-OK-134" - }, - "strain": { - "value": "OP351286" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G84534A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "G185991A", - "-196601A", - "-196602A", - "-196603A" - ], - "OPG105": [ - "D1137N" - ], - "OPG210": [ - "D1546N" - ] - }, - "labels": { - "aa": "OPG105: D1137N; OPG210: D1546N" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000155", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C24995T", - "G85774A", - "G148427A", - "G189258A" - ], - "OPG040": [ - "D162N" - ], - "OPG107": [ - "R88K" - ] - }, - "labels": { - "aa": "OPG040: D162N; OPG107: R88K" - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-2906/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-05-20" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-2906/2022" - }, - "strain": { - "value": "ON880505" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3193/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-05-31" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3193/2022" - }, - "strain": { - "value": "ON880510" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179048-", - "A179049-", - "A179050-", - "C179051-", - "T179052-", - "G179053-", - "A179054-", - "A179055-", - "G179056-", - "T179057-", - "T179058-", - "T179059-", - "A179060-", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-" - ] - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3532/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Marchand-Austin,A., Eshaghi,A., Patel,S.N., Hasso,M., Gubbay,J.B., Olsha,R.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Marchand-Austin,A., Eshaghi,A., Patel,S.N., Hasso,M., Gubbay,J.B., Olsha,R." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-06-07" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3532/2022" - }, - "strain": { - "value": "ON983163" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/CAN/UN-NML-4103/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Griffiths,E., Jolly,G., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Griffiths,E., Jolly,G., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-07-04" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-4103/2022" - }, - "strain": { - "value": "OP279035" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "hMpxV/USA/CA-CDPH-1000083/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., Bell,J., Hacker,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-13" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/USA/CA-CDPH-1000083/2022" - }, - "strain": { - "value": "OQ121037" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - }, - { - "name": "NODE_0000156", - "node_attrs": { - "div": 67, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G45236A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-3936/2022", - "node_attrs": { - "div": 68, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Jolly,G., Griffiths,E., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Jolly,G., Griffiths,E., Charest,H., Levade,I., Fafard,J." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-06-30" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3936/2022" - }, - "strain": { - "value": "OP062236" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G132531A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T" - ] - } - } - }, - { - "name": "NODE_0000157", - "node_attrs": { - "div": 68, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G174962A" - ], - "OPG204": [ - "R144K" - ] - }, - "labels": { - "aa": "OPG204: R144K" - } - }, - "children": [ - { - "name": "MPX_J6xzTO_9000286", - "node_attrs": { - "div": 68, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_J6xzTO_9000286" - }, - "strain": { - "value": "OP415246" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPX_J6xzTO_9000287", - "node_attrs": { - "div": 69, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_J6xzTO_9000287" - }, - "strain": { - "value": "OP415247" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C81418T" - ], - "OPG105": [ - "S98L" - ] - }, - "labels": { - "aa": "OPG105: S98L" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000158", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G36259A", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G174543A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "A179173-", - "T179174-", - "T179175-", - "-196603A" - ] - } - }, - "children": [ - { - "name": "hMPX/USA/CA-LACPHL-MA00175/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-04" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPX/USA/CA-LACPHL-MA00175/2022" - }, - "strain": { - "value": "OP580608" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G13224A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "C179154-", - "C179163-", - "C179172-" - ], - "OPG024": [ - "S2L" - ] - }, - "labels": { - "aa": "OPG024: S2L" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI496", - "node_attrs": { - "div": 67, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI496" - }, - "strain": { - "value": "OP626135" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T595-", - "C40251T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "C154472T", - "G167517A", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "A196603-" - ], - "OPG058": [ - "D62N" - ], - "OPG181": [ - "H21Y" - ], - "OPG193": [ - "E62K" - ] - }, - "labels": { - "aa": "OPG058: D62N; OPG181: H21Y; OPG193: E62K" - } - } - }, - { - "name": "MPX/Human/USA/CA-LACPHL-MA00247/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-16" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX/Human/USA/CA-LACPHL-MA00247/2022" - }, - "strain": { - "value": "OP722506" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "C179154-", - "C179163-", - "C179172-" - ] - } - } - }, - { - "name": "MPXV_USA_2022_CA0011", - "node_attrs": { - "div": 65, - "author": { - "author": "Gigante,C., Ventura,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nash,J., Li,Y.", - "value": "Gigante,C., Ventura,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nash,J., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_CA0011" - }, - "strain": { - "value": "OP881943" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G174830T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG204": [ - "R100L" - ] - }, - "labels": { - "aa": "OPG204: R100L" - } - } - }, - { - "name": "NY-NYCPHL-001021", - "node_attrs": { - "div": 64, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-05" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-001021" - }, - "strain": { - "value": "OQ469225" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ] - } - } - }, - { - "name": "NODE_0000159", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C177720T" - ], - "OPG205": [ - "R689C" - ] - }, - "labels": { - "aa": "OPG205: R689C" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-108160/2022", - "node_attrs": { - "div": 67, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-10-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-108160/2022" - }, - "strain": { - "value": "OQ503748" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A80755C", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G159203A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG104": [ - "C89G" - ], - "OPG185": [ - "G96E" - ] - }, - "labels": { - "aa": "OPG104: C89G; OPG185: G96E" - } - } - }, - { - "name": "hMpxV/USA/CACDPH1MPX1000185/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-12-21" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/USA/CACDPH1MPX1000185/2022" - }, - "strain": { - "value": "OQ547900" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T6975-", - "G92733A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "C179154-", - "C179163-", - "C179172-" - ], - "OPG113": [ - "E335K" - ] - }, - "labels": { - "aa": "OPG113: E335K" - } - } - } - ] - }, - { - "name": "NODE_0000160", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C25967T", - "C172792T", - "C179154-", - "C179163-", - "C179172-" - ], - "OPG042": [ - "W377*" - ] - }, - "labels": { - "aa": "OPG042: W377*" - } - }, - "children": [ - { - "name": "NODE_0000161", - "node_attrs": { - "div": 67, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T495-", - "A496-", - "T497-", - "C97805T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T" - ], - "OPG117": [ - "P586L" - ] - }, - "labels": { - "aa": "OPG117: P586L" - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00343/2022", - "node_attrs": { - "div": 67, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-11-10" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00343/2022" - }, - "strain": { - "value": "OP920681" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00469/2022", - "node_attrs": { - "div": 69, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-11-18" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00469/2022" - }, - "strain": { - "value": "OQ644775" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C100640T", - "C105632T" - ], - "OPG124": [ - "E113K" - ] - }, - "labels": { - "aa": "OPG124: E113K" - } - } - } - ] - }, - { - "name": "NODE_0000162", - "node_attrs": { - "div": 67, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A163469T" - ], - "OPG189": [ - "E46V" - ] - }, - "labels": { - "aa": "OPG189: E46V" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-093664/2022", - "node_attrs": { - "div": 68, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-093664/2022" - }, - "strain": { - "value": "OQ503767" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G54182A", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179154C", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG071": [ - "A86V" - ] - }, - "labels": { - "aa": "OPG071: A86V" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00452/2022", - "node_attrs": { - "div": 75, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-10-12" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00452/2022" - }, - "strain": { - "value": "OQ503786" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.4" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G70435A", - "C125412T", - "C141442T", - "C141511T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "G158709A", - "T172792C", - "G175698A", - "G176439A" - ], - "OPG145": [ - "S489L" - ], - "OPG161": [ - "S114L", - "S137F" - ], - "OPG205": [ - "D15N", - "D262N" - ] - }, - "labels": { - "aa": "OPG145: S489L; OPG161: S114L, S137F; OPG205: D15N, D262N" - } - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000163", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G1302A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150565G", - "-150566A", - "-150567T", - "C182950T" - ], - "OPG210": [ - "S532L" - ] - }, - "labels": { - "aa": "OPG210: S532L", - "clade": "B.1.12" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/ON/RKI866", - "node_attrs": { - "div": 62, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI866" - }, - "strain": { - "value": "OQ773485" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-" - ] - } - } - }, - { - "name": "NODE_0000164", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G78328A", - "C195908T" - ], - "OPG001": [ - "L92F" - ] - }, - "labels": { - "aa": "OPG001: L92F" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI399", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI399" - }, - "strain": { - "value": "OP524001" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T" - ] - } - } - }, - { - "name": "NODE_0000165", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C57550T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150565-", - "A150566-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - }, - "children": [ - { - "name": "MPX_BhVKjm_9000232", - "node_attrs": { - "div": 64, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_BhVKjm_9000232" - }, - "strain": { - "value": "OP415206" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPX_BhVKjm_9000233", - "node_attrs": { - "div": 64, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_BhVKjm_9000233" - }, - "strain": { - "value": "OP415207" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000166", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A1302G", - "G111084A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150565-", - "A150566-", - "T150567-" - ] - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-3342/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-06-01" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3342/2022" - }, - "strain": { - "value": "ON880540" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G121510A" - ] - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3448/2022", - "node_attrs": { - "div": 63, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-06-03" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3448/2022" - }, - "strain": { - "value": "ON880548" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3276/2022", - "node_attrs": { - "div": 63, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Chapel,M., Tyler,A., Haidl,E., Domselaar,G.V., Antonation,K., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Jolly,G., Fafard,J., Charest,H., Levade,I.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Chapel,M., Tyler,A., Haidl,E., Domselaar,G.V., Antonation,K., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Jolly,G., Fafard,J., Charest,H., Levade,I." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-05-31" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3276/2022" - }, - "strain": { - "value": "OP013003" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179015-", - "A179016-", - "T179017-", - "T179018-", - "T179019-", - "G179020-", - "T179021-", - "C179022-", - "G179023-", - "A179024-", - "G179025-", - "T179026-", - "A179027-", - "T179028-", - "G179029-", - "A179030-", - "A179031-", - "T179032-", - "A179033-", - "C179034-", - "G179035-", - "G179036-", - "A179037-", - "G179038-", - "T179039-", - "A179040-", - "C179041-", - "A179042-", - "A179043-", - "A179044-", - "C179045-", - "A179046-", - "T179047-", - "A179048-", - "A179049-", - "A179050-", - "C179051-", - "T179052-", - "G179053-", - "A179054-", - "A179055-", - "G179056-", - "T179057-", - "T179058-", - "T179059-", - "A179060-", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-" - ] - } - } - }, - { - "name": "hMpxV/Human/USA/IL-RIPHL-MPXV_10015/2022", - "node_attrs": { - "div": 71, - "author": { - "author": "Barbian,H., Green,S., Kunstman,K., Araujo Perez,F., Bobrovska,S., Hayden,M., Moore,N.", - "value": "Barbian,H., Green,S., Kunstman,K., Araujo Perez,F., Bobrovska,S., Hayden,M., Moore,N." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-10-18" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/Human/USA/IL-RIPHL-MPXV_10015/2022" - }, - "strain": { - "value": "OQ121959" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G4859A", - "C24077T", - "C24231T", - "G67582A", - "C88319T", - "G97405A", - "C101656T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "G165506A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "C192351T", - "A196604-" - ], - "NBT03_gp175": [ - "S433L" - ], - "OPG015": [ - "S433L" - ], - "OPG085": [ - "S317L" - ], - "OPG109": [ - "A377T" - ], - "OPG117": [ - "E453K" - ], - "OPG190": [ - "E129K" - ] - }, - "labels": { - "aa": "NBT03_gp175: S433L; OPG015: S433L; OPG085: S317L; OPG109: A377T; OPG117: E453K; OPG190: E129K" - } - } - }, - { - "name": "NODE_0000167", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G98233A", - "G98455A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG117": [ - "D729N" - ], - "OPG118": [ - "G4R" - ] - }, - "labels": { - "aa": "OPG117: D729N; OPG118: G4R" - } - }, - "children": [ - { - "name": "MPX/BR0002/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Coletti,T.M., Ghilardi,F., khan,M.J., Claro,I.M., Valenca,I.N., Faria,N.R., Sabino,E.C.", - "value": "Coletti,T.M., Ghilardi,F., khan,M.J., Claro,I.M., Valenca,I.N., Faria,N.R., Sabino,E.C." - }, - "country": { - "value": "Brazil" - }, - "date": { - "value": "2022-06-14" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Imperial College London, School of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX/BR0002/2022" - }, - "strain": { - "value": "ON880413" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C76334T", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "G173165-", - "C173166-", - "G173167-", - "G173168-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-" - ], - "OPG097": [ - "R181K" - ] - }, - "labels": { - "aa": "OPG097: R181K" - } - } - }, - { - "name": "NODE_0000168", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G98456A" - ], - "OPG118": [ - "R4K" - ] - }, - "labels": { - "aa": "OPG118: R4K" - } - }, - "children": [ - { - "name": "MPXV22/human/USA-NE-25", - "node_attrs": { - "div": 68, - "author": { - "author": "Tegomoh,B., Cross,S.T., Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., Pratt,C.B., Warden,D.E., Iwen,P.C., Donahue,M., Wiley,M.R.", - "value": "Tegomoh,B., Cross,S.T., Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., Pratt,C.B., Warden,D.E., Iwen,P.C., Donahue,M., Wiley,M.R." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-25" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV22/human/USA-NE-25" - }, - "strain": { - "value": "OP171919" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "G102694A", - "G160484A", - "-196601A", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3972/2022", - "node_attrs": { - "div": 69, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Griffiths,E., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Griffiths,E., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-07-04" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3972/2022" - }, - "strain": { - "value": "OP270022" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G3361A", - "C152970T", - "G181349A", - "C193849T" - ], - "OPG003": [ - "S416L" - ] - }, - "labels": { - "aa": "OPG003: S416L" - } - } - }, - { - "name": "NY-NYCPHL-000596", - "node_attrs": { - "div": 68, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-01" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000596" - }, - "strain": { - "value": "OQ468711" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T67849G", - "T108222C", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG085": [ - "N228T" - ], - "OPG127": [ - "M202V" - ] - }, - "labels": { - "aa": "OPG085: N228T; OPG127: M202V" - } - } - }, - { - "name": "NY-NYCPHL-001039", - "node_attrs": { - "div": 66, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-24" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-001039" - }, - "strain": { - "value": "OQ469233" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV22/human/USA-NE-324", - "node_attrs": { - "div": 69, - "author": { - "author": "Tegomoh,B., Cross,S.T., Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., Pratt,C.B., Warden,D.E., Iwen,P.C., Donahue,M., Wiley,M.R.", - "value": "Tegomoh,B., Cross,S.T., Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., Pratt,C.B., Warden,D.E., Iwen,P.C., Donahue,M., Wiley,M.R." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-29" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV22/human/USA-NE-324" - }, - "strain": { - "value": "OQ626770" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "C3438T", - "C10484T", - "A61974G", - "G193772A", - "-196601A", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "MPXV_USA_2022_TN0019", - "node_attrs": { - "div": 69, - "author": { - "author": "Gigante,C., Thomas,L., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Dunn,J., Li,Y.", - "value": "Gigante,C., Thomas,L., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Dunn,J., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-12-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_TN0019" - }, - "strain": { - "value": "OR209309" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C93601T", - "C94418T", - "T133078-", - "T133079-", - "C136029T" - ], - "OPG113": [ - "A624V" - ], - "OPG114": [ - "E84K" - ] - }, - "labels": { - "aa": "OPG113: A624V; OPG114: E84K" - } - } - }, - { - "name": "NODE_0000169", - "node_attrs": { - "div": 67, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C24231T" - ] - } - }, - "children": [ - { - "name": "hMPXV-IHU00008", - "node_attrs": { - "div": 68, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "country": { - "value": "France" - }, - "date": { - "value": "2022-07-05" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPXV-IHU00008" - }, - "strain": { - "value": "OP382485" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T591-", - "A592-", - "-594T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "G184227A" - ], - "OPG210": [ - "D958N" - ] - }, - "labels": { - "aa": "OPG210: D958N" - } - } - }, - { - "name": "BOL-UNIMOL-MPX-293015-L", - "node_attrs": { - "div": 67, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-08-24" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "BOL-UNIMOL-MPX-293015-L" - }, - "strain": { - "value": "OP390179" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "MPX_ilzdZn_9000269", - "node_attrs": { - "div": 68, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_ilzdZn_9000269" - }, - "strain": { - "value": "OP415236" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G23457A", - "A178020-", - "T178021-", - "A178022-", - "A178023-", - "T178024-", - "G178025-", - "A178026-", - "A178027-", - "T178028-", - "A178029-", - "C178030-", - "A178031-", - "C178032-", - "A178033-", - "T178034-", - "A178035-", - "C178036-", - "A178037-" - ], - "OPG039": [ - "S221F" - ] - }, - "labels": { - "aa": "OPG039: S221F" - } - } - }, - { - "name": "NY-NYCPHL-000349", - "node_attrs": { - "div": 69, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-11" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000349" - }, - "strain": { - "value": "OQ468959" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C41419T", - "C105217T" - ], - "OPG061": [ - "D156N" - ], - "OPG124": [ - "R251K" - ] - }, - "labels": { - "aa": "OPG061: D156N; OPG124: R251K" - } - } - }, - { - "name": "NODE_0000170", - "node_attrs": { - "div": 68, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G61102A" - ], - "OPG080": [ - "S306F" - ] - }, - "labels": { - "aa": "OPG080: S306F" - } - }, - "children": [ - { - "name": "MPXV/UZ_REGA_214/Belgium/2022", - "node_attrs": { - "div": 68, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-08-08" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_214/Belgium/2022" - }, - "strain": { - "value": "OR095032" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/UZ_REGA_215/Belgium/2022", - "node_attrs": { - "div": 68, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-08-08" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_215/Belgium/2022" - }, - "strain": { - "value": "OR095033" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000171", - "node_attrs": { - "div": 67, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G153910A" - ], - "OPG180": [ - "E407K" - ] - }, - "labels": { - "aa": "OPG180: E407K" - } - }, - "children": [ - { - "name": "NY-NYCPHL-000705", - "node_attrs": { - "div": 67, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-19" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000705" - }, - "strain": { - "value": "OQ419069" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-" - ] - } - } - }, - { - "name": "MPXV_USA_2022_NY0039", - "node_attrs": { - "div": 68, - "author": { - "author": "Gigante,C., Ruiz,V., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Wang,J., Li,Y.", - "value": "Gigante,C., Ruiz,V., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Wang,J., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-10-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_NY0039" - }, - "strain": { - "value": "OQ427114" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G71407A", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-" - ], - "OPG091": [ - "R13K" - ] - }, - "labels": { - "aa": "OPG091: R13K" - } - } - }, - { - "name": "NY-NYCPHL-000821", - "node_attrs": { - "div": 67, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-14" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000821" - }, - "strain": { - "value": "OQ468513" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-" - ] - } - } - }, - { - "name": "MPXV/Human/USA/UT-UPHL-82200369/2022", - "node_attrs": { - "div": 69, - "author": { - "author": "Iverson,T., Oakeson,K.F., Young,E.L., Wagner,J., Hergert,J.", - "value": "Iverson,T., Oakeson,K.F., Young,E.L., Wagner,J., Hergert,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-06" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Utah Public Health Laboratory, Utah Public Health Laboratory Infectious Disease submission group" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/UT-UPHL-82200369/2022" - }, - "strain": { - "value": "OR026631" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G11924A", - "A37326C", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-" - ], - "OPG023": [ - "S326L" - ], - "OPG056": [ - "I570R" - ] - }, - "labels": { - "aa": "OPG023: S326L; OPG056: I570R" - } - } - }, - { - "name": "NODE_0000172", - "node_attrs": { - "div": 69, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C21910T", - "G28483A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T" - ], - "OPG037": [ - "R175K" - ] - }, - "labels": { - "aa": "OPG037: R175K" - } - }, - "children": [ - { - "name": "NY-NYCPHL-001187", - "node_attrs": { - "div": 69, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-01-05" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-001187" - }, - "strain": { - "value": "OQ419087" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150577-", - "A150578-", - "T150579-", - "A150580-", - "T150581-", - "G150582-", - "A150583-", - "T150584-" - ] - } - } - }, - { - "name": "NY-NYCPHL-001188", - "node_attrs": { - "div": 71, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-01-05" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-001188" - }, - "strain": { - "value": "OQ419088" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C47537T", - "C104712T", - "T150587-", - "A150588-", - "T150589-", - "G150590-" - ], - "OPG123": [ - "R120K" - ] - }, - "labels": { - "aa": "OPG123: R120K" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00490/2023", - "node_attrs": { - "div": 72, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-02-10" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00490/2023" - }, - "strain": { - "value": "OQ918701" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.12" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G39552A", - "T57420-", - "A57421-", - "C57422-", - "A57423-", - "A57424-", - "A57425-", - "A57426-", - "A57427-", - "G57428-", - "G57429-", - "A57430-", - "C57431-", - "A57432-", - "T57433-", - "G57434-", - "T57435-", - "A57436-", - "A57437-", - "A57438-", - "C57439-", - "T57440-", - "G132490A", - "C150443T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-" - ], - "OPG057": [ - "S215F" - ], - "OPG075": [ - "K20X", - "F21-", - "T22-", - "C23-", - "P24-", - "F25-", - "C26-", - "R27X", - "*109X" - ], - "OPG176": [ - "T212I" - ] - }, - "labels": { - "aa": "OPG057: S215F; OPG075: K20X, F21-, T22-, C23-, P24-, F25-, C26-, R27X, *109X; OPG176: T212I" - } - } - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000173", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G36617A", - "-150551G", - "-150556G", - "-150559G", - "-150560G", - "-150565G", - "C159779T" - ], - "OPG055": [ - "S156L" - ], - "OPG185": [ - "S288L" - ] - }, - "labels": { - "aa": "OPG055: S156L; OPG185: S288L", - "clade": "B.1.14" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI011", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI011" - }, - "strain": { - "value": "ON694342" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "A192404-", - "G192405-", - "T192406-", - "C192407-", - "A192408-", - "T192409-", - "A192410-", - "A192411-", - "G192412-", - "T192413-", - "T192414-", - "A192415-", - "G192416-", - "T192417-", - "T192418-", - "A192419-", - "A192420-", - "G192421-", - "T192422-", - "C192423-", - "A192424-", - "T192425-", - "A192426-", - "A192427-", - "G192428-", - "T192429-", - "T192430-", - "A192431-", - "G192432-", - "T192433-", - "T192434-", - "A192435-" - ] - } - } - }, - { - "name": "MPXV_USA_2022_NY002", - "node_attrs": { - "div": 63, - "author": { - "author": "Gigante,C.M., Hughes,S., Seabolt,M.H., Zhao,H., Wilkins,K., Respress,J., Howard,D., Batra,D., McCollum,A., Hutson,C., Davidson,W., Rao,A., Baumgartner,J., Li,Y.", - "value": "Gigante,C.M., Hughes,S., Seabolt,M.H., Zhao,H., Wilkins,K., Respress,J., Howard,D., Batra,D., McCollum,A., Hutson,C., Davidson,W., Rao,A., Baumgartner,J., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_NY002" - }, - "strain": { - "value": "ON959133" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G150551-", - "G150556-", - "G150559-", - "G150560-", - "G150565-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A196604-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI155", - "node_attrs": { - "div": 65, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI155" - }, - "strain": { - "value": "ON959169" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "G168365A", - "G170929A" - ], - "OPG195": [ - "E46K" - ] - }, - "labels": { - "aa": "OPG195: E46K" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI302", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI302" - }, - "strain": { - "value": "OP355563" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "A188349-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI314", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI314" - }, - "strain": { - "value": "OP355572" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C84008T", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "A188349-" - ] - } - } - }, - { - "name": "MPXV_USA_2022_TX0010", - "node_attrs": { - "div": 66, - "author": { - "author": "Gigante,C.M., Kubin,G., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S.L., Li,Y.", - "value": "Gigante,C.M., Kubin,G., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S.L., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_TX0010" - }, - "strain": { - "value": "OP378704" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "-595T", - "C8552T", - "C8597T", - "G46179A", - "G150551-", - "G150556-", - "G150559-", - "G150560-", - "G150565-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "-196602A", - "-196603A" - ], - "OPG065": [ - "S102L" - ] - }, - "labels": { - "aa": "OPG065: S102L" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI668", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI668" - }, - "strain": { - "value": "OQ274887" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "G150551-", - "G150556-", - "G150559-", - "G150560-", - "-150566A", - "-150567T", - "A152668-", - "T152680-" - ] - } - } - }, - { - "name": "NY-NYCPHL-000273", - "node_attrs": { - "div": 63, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-01" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000273" - }, - "strain": { - "value": "OQ468471" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "G150556-", - "G150559-", - "G150560-", - "G150565-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "NY-NYCPHL-000042", - "node_attrs": { - "div": 64, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-05-25" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000042" - }, - "strain": { - "value": "OQ469020" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G61231A", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG080": [ - "S263F" - ] - }, - "labels": { - "aa": "OPG080: S263F" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI725", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI725" - }, - "strain": { - "value": "OQ547752" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C3837T", - "G150550-", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150566A", - "-150567T", - "G181049-" - ], - "OPG209": [ - "G178X", - "*191X" - ] - }, - "labels": { - "aa": "OPG209: G178X, *191X" - } - } - }, - { - "name": "NY-NYCPHL-000937", - "node_attrs": { - "div": 63, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-08" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000937" - }, - "strain": { - "value": "OQ565519" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150564T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "Lesion", - "node_attrs": { - "div": 65, - "author": { - "author": "Pettke,A., Filen,F., Asgeirsson,H., Glans,H., Widgren,K., Muradrasoli,S., Helgesson,S., Karlberg,M.L., Walai,N., Bjerkner,A., Gourle,H., Lindsjo,O.K., Sonden,K.", - "value": "Pettke,A., Filen,F., Asgeirsson,H., Glans,H., Widgren,K., Muradrasoli,S., Helgesson,S., Karlberg,M.L., Walai,N., Bjerkner,A., Gourle,H., Lindsjo,O.K., Sonden,K." - }, - "country": { - "value": "Sweden" - }, - "date": { - "value": "2022-05-22" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Public Health Agency of Sweden, Unit for Laboratory Development and Technology Transfer , Folkhalsomyndigheten, 171 82 Solna" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Lesion" - }, - "strain": { - "value": "OX009124" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "T597-", - "T598-", - "T599-", - "T600-", - "A8048-", - "A28524-", - "A28525-", - "T47051-", - "T76079-", - "T88831-", - "A91698-", - "A92904-", - "T103362-", - "T104686-", - "T148344A", - "A148345T", - "G150551-", - "G150556-", - "G150559-", - "G150560-", - "G150565-", - "A151674-", - "A162901-", - "T163338-", - "T163592-", - "A170723-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A196604-" - ], - "OPG044": [ - "E145X", - "*150X" - ], - "OPG066": [ - "K126X", - "*260X" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG109": [ - "K206X", - "*796X" - ], - "OPG113": [ - "K392X", - "*846X" - ], - "OPG123": [ - "T129X", - "N570X", - "*632X" - ], - "OPG178": [ - "K56X", - "*205X" - ], - "OPG188": [ - "K436X", - "*504X" - ], - "OPG189": [ - "D2X", - "I87X", - "*562X" - ], - "OPG198": [ - "Q229X", - "*283X" - ] - }, - "labels": { - "aa": "OPG044: E145X, *150X; OPG066: K126X, *260X; OPG097: K266X, *345X; OPG109: K206X, *796X; OPG113: K392X, *846X; OPG123: T129X, N570X, *632X; OPG178: K56X, *205X; OPG188: K436X, *504X; OPG189: D2X, I87X, *562X; OPG198: Q229X, *283X" - } - } - }, - { - "name": "NODE_0000174", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G28021A" - ] - } - }, - "children": [ - { - "name": "MPX/Human/USA/CA-LACPHL-MA00137/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-09" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX/Human/USA/CA-LACPHL-MA00137/2022" - }, - "strain": { - "value": "OP539922" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G109793A", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "G168211-", - "G168212-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "G181818A" - ], - "OPG210": [ - "A155T" - ] - }, - "labels": { - "aa": "OPG210: A155T" - } - } - }, - { - "name": "NODE_0000175", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C148666T", - "G150551-", - "G150556-", - "G150559-", - "G150560-", - "G150565-" - ], - "OPG174": [ - "A244T" - ] - }, - "labels": { - "aa": "OPG174: A244T" - } - }, - "children": [ - { - "name": "MPXV/Human/USA/UT-UPHL-82200381/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Iverson,T., Oakeson,K.F., Young,E.L., Wagner,J., Hergert,J.", - "value": "Iverson,T., Oakeson,K.F., Young,E.L., Wagner,J., Hergert,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-10" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Utah Public Health Laboratory, Utah Public Health Laboratory Infectious Disease submission group" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/UT-UPHL-82200381/2022" - }, - "strain": { - "value": "OR026628" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Human/USA/UT-UPHL-82200382/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Iverson,T., Oakeson,K.F., Young,E.L., Wagner,J., Hergert,J.", - "value": "Iverson,T., Oakeson,K.F., Young,E.L., Wagner,J., Hergert,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-09" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Utah Public Health Laboratory, Utah Public Health Laboratory Infectious Disease submission group" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/UT-UPHL-82200382/2022" - }, - "strain": { - "value": "OR026629" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000176", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G158617A", - "C183790T" - ], - "OPG210": [ - "S812L" - ] - }, - "labels": { - "aa": "OPG210: S812L" - } - }, - "children": [ - { - "name": "NODE_0000177", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C132437T", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI102", - "node_attrs": { - "div": 67, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI102" - }, - "strain": { - "value": "ON929060" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C127245T" - ], - "OPG149": [ - "S17L" - ] - }, - "labels": { - "aa": "OPG149: S17L" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI558", - "node_attrs": { - "div": 66, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI558" - }, - "strain": { - "value": "OP764616" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T179065-", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-" - ] - } - } - } - ] - }, - { - "name": "NODE_0000178", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C170573T" - ], - "OPG198": [ - "S179L" - ] - }, - "labels": { - "aa": "OPG198: S179L" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI562", - "node_attrs": { - "div": 68, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI562" - }, - "strain": { - "value": "OP764620" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T8011G", - "C33579T", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T" - ], - "OPG051": [ - "G24E" - ] - }, - "labels": { - "aa": "OPG051: G24E" - } - } - }, - { - "name": "NODE_0000179", - "node_attrs": { - "div": 67, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C22880T", - "G150551-", - "G150556-", - "G150559-", - "G150560-", - "G150565-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG038": [ - "E94K" - ] - }, - "labels": { - "aa": "OPG038: E94K" - } - }, - "children": [ - { - "name": "MPXV/UZ_REGA_40", - "node_attrs": { - "div": 67, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-07-27" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_40" - }, - "strain": { - "value": "OR035646" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/UZ_REGA_147/Belgium/2022", - "node_attrs": { - "div": 67, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-07-05" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_147/Belgium/2022" - }, - "strain": { - "value": "OR086956" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T149487-", - "A149488-", - "C149489-", - "G149490-", - "T149491-", - "T149492-", - "G149493-", - "A149494-", - "A149495-", - "C149496-", - "A149497-", - "A149498-", - "G149499-", - "T149500-", - "C149501-", - "C149502-", - "A149503-" - ], - "OPG175": [ - "Y16-", - "V17-", - "E18-", - "Q19-", - "V20-", - "H21X", - "*126X" - ] - }, - "labels": { - "aa": "OPG175: Y16-, V17-, E18-, Q19-, V20-, H21X, *126X" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000180", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "G171270A", - "-196603A" - ], - "OPG199": [ - "D95N" - ] - }, - "labels": { - "aa": "OPG199: D95N" - } - }, - "children": [ - { - "name": "hMPXV-IHU00015", - "node_attrs": { - "div": 65, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "country": { - "value": "France" - }, - "date": { - "value": "2022-07-22" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPXV-IHU00015" - }, - "strain": { - "value": "OP382492" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G161913A", - "A178998-", - "T178999-", - "T179000-", - "G179001-", - "T179002-", - "G179003-", - "T179004-", - "A179005-", - "C179006-", - "A179007-", - "C179008-", - "G179009-", - "A179010-", - "T179011-", - "A179012-", - "C179013-", - "C179014-", - "A179015-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "T196584-", - "C196585-", - "A196586-" - ] - } - } - }, - { - "name": "hMPXV-IHU00016", - "node_attrs": { - "div": 67, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "country": { - "value": "France" - }, - "date": { - "value": "2022-07-22" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPXV-IHU00016" - }, - "strain": { - "value": "OP382493" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G25999A", - "G97417A", - "G100939A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "C179045-", - "A179046-", - "T179047-", - "A179048-", - "A179049-", - "A179050-", - "C179051-", - "T179052-", - "G179053-", - "A179054-", - "A179055-", - "G179056-", - "T179057-", - "T179058-", - "T179059-", - "A179060-", - "A179061-", - "C179062-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A196603-" - ], - "OPG042": [ - "Q367*" - ], - "OPG117": [ - "E457K" - ] - }, - "labels": { - "aa": "OPG042: Q367*; OPG117: E457K" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI320", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI320" - }, - "strain": { - "value": "OP494266" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0486/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-09" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0486/2022" - }, - "strain": { - "value": "OP555562" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0501/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-16" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0501/2022" - }, - "strain": { - "value": "OP555575" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0573/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-09-06" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0573/2022" - }, - "strain": { - "value": "OP555644" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594A", - "-595T", - "C93713T", - "G158549A", - "-196601A", - "-196602A", - "A196616T" - ] - } - } - }, - { - "name": "Slovenia-MPXV-10-2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "country": { - "value": "Slovenia" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Slovenia-MPXV-10-2022" - }, - "strain": { - "value": "OP605553" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594A", - "-595T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G196443-", - "A196444-", - "A196445-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI507", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI507" - }, - "strain": { - "value": "OP689660" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "T597-" - ] - } - } - }, - { - "name": "NY-NYCPHL-001139", - "node_attrs": { - "div": 64, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-06" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-001139" - }, - "strain": { - "value": "OQ468597" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.14" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000181", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G5595A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C191615T" - ], - "NBT03_gp175": [ - "Q188*" - ], - "OPG015": [ - "Q188*" - ] - }, - "labels": { - "aa": "NBT03_gp175: Q188*; OPG015: Q188*", - "clade": "B.1.8" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI235", - "node_attrs": { - "div": 62, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI235" - }, - "strain": { - "value": "OP215224" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000182", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G161296A" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI104", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI104" - }, - "strain": { - "value": "ON929062" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C186220T" - ], - "OPG210": [ - "A1622V" - ] - }, - "labels": { - "aa": "OPG210: A1622V" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI275", - "node_attrs": { - "div": 67, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI275" - }, - "strain": { - "value": "OP263630" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C86391T", - "C103786T", - "C160088T", - "G186255A" - ], - "OPG108": [ - "M223I" - ], - "OPG123": [ - "E429K" - ], - "OPG210": [ - "E1634K" - ] - }, - "labels": { - "aa": "OPG108: M223I; OPG123: E429K; OPG210: E1634K" - } - } - }, - { - "name": "MPXV_UK_2022_9000183", - "node_attrs": { - "div": 63, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-06-29" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000183" - }, - "strain": { - "value": "OP331337" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G902A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "C196308T" - ], - "OPG001": [ - "S225L" - ] - }, - "labels": { - "aa": "OPG001: S225L" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI341", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI341" - }, - "strain": { - "value": "OP484664" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0508/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-16" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0508/2022" - }, - "strain": { - "value": "OP555581" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C4648T", - "C172765T", - "G192562A" - ] - } - } - }, - { - "name": "Monkeypox/PT0538/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-23" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0538/2022" - }, - "strain": { - "value": "OP555609" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G902A", - "C25269T", - "G25692A", - "C196308T", - "-196603A" - ], - "OPG001": [ - "S225L" - ] - }, - "labels": { - "aa": "OPG001: S225L" - } - } - }, - { - "name": "MPXV/UZ_REGA_17", - "node_attrs": { - "div": 64, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-07-19" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_17" - }, - "strain": { - "value": "OR030928" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G902A", - "C68981T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "C196308T" - ], - "OPG001": [ - "S225L" - ], - "OPG087": [ - "S42L" - ] - }, - "labels": { - "aa": "OPG001: S225L; OPG087: S42L" - } - } - }, - { - "name": "MPXV/UZ_REGA_224/Belgium/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logis,A.-S., Bloemen,M., Van Holm,B., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logis,A.-S., Bloemen,M., Van Holm,B., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-08-12" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_224/Belgium/2022" - }, - "strain": { - "value": "OR095042" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G34298T", - "C37048T", - "G70190A", - "A146964-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG089": [ - "E109K" - ] - }, - "labels": { - "aa": "OPG089: E109K" - } - } - }, - { - "name": "NODE_0000183", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C80545T" - ], - "OPG103": [ - "S182L" - ] - }, - "labels": { - "aa": "OPG103: S182L" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI540", - "node_attrs": { - "div": 65, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI540" - }, - "strain": { - "value": "OP715820" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G105792A" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI585", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI585" - }, - "strain": { - "value": "OP837347" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI895", - "node_attrs": { - "div": 66, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI895" - }, - "strain": { - "value": "OQ773514" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G77807A", - "C163441T" - ], - "OPG099": [ - "R48K" - ], - "OPG189": [ - "Q37*" - ] - }, - "labels": { - "aa": "OPG099: R48K; OPG189: Q37*" - } - } - }, - { - "name": "NODE_0000184", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G102614A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "C170573T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG122": [ - "V63I" - ], - "OPG198": [ - "S179L" - ] - }, - "labels": { - "aa": "OPG122: V63I; OPG198: S179L" - } - }, - "children": [ - { - "name": "MPXV/UZ_REGA_108", - "node_attrs": { - "div": 66, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-10-28" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_108" - }, - "strain": { - "value": "OR035714" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/UZ_REGA_244/Belgium/2022", - "node_attrs": { - "div": 67, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-08-16" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_244/Belgium/2022" - }, - "strain": { - "value": "OR095062" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C62305T" - ] - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000185", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G78034A", - "C80111T" - ], - "OPG099": [ - "D124N" - ] - }, - "labels": { - "aa": "OPG099: D124N" - } - }, - "children": [ - { - "name": "MPXV/ES0001/HUGTiP/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Martinez-Puchol,S., Coello,A., Bordoy,A.E., Soler,L., Panisello,D., Gonzalez-Gomez,S., Clara,G., Paris de Leon,A., Not,A., Hernandez,A., Bofill-Mas,S., Saludes,V., Blanco,I., Martro,E., Cardona,P.-J.", - "value": "Martinez-Puchol,S., Coello,A., Bordoy,A.E., Soler,L., Panisello,D., Gonzalez-Gomez,S., Clara,G., Paris de Leon,A., Not,A., Hernandez,A., Bofill-Mas,S., Saludes,V., Blanco,I., Martro,E., Cardona,P.-J." - }, - "country": { - "value": "Spain" - }, - "date": { - "value": "2022-05-20" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Microbiology, Hospital Universitari Germans Trias i Pujol, Spain" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/ES0001/HUGTiP/2022" - }, - "strain": { - "value": "ON622718" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C14113-", - "-133164C", - "-133165A", - "-133166A", - "-133167T", - "-133168C", - "-133169T", - "-133170T", - "-133171T", - "-133172C", - "-133173T", - "T139150C", - "A178796-", - "T178797-", - "G178798-", - "G178799-", - "G178800-", - "A178801-", - "A178802-", - "T178803-", - "T178804-", - "G178805-", - "G178806-", - "T178807-", - "A178808-", - "A178809-", - "C178810-", - "G178811-", - "A178812-", - "T178813-", - "G178814-", - "A178815-", - "C178816-", - "A178817-", - "G178818-", - "A178819-", - "A178820-", - "A178821-", - "G178822-", - "C178823-", - "A178824-", - "G178825-", - "A178826-", - "T178827-", - "T178828-", - "G178829-", - "T178830-", - "C178831-", - "A178832-", - "G178833-", - "C178834-", - "T178835-", - "C178836-", - "T178837-", - "G178838-", - "C178839-", - "A178840-", - "T178841-", - "A178842-", - "C178843-", - "T178844-", - "A178845-", - "T178846-", - "T178847-", - "C178848-", - "T178849-", - "T178850-", - "C178851-", - "A178852-", - "T178853-", - "G178854-", - "A178855-", - "C178856-", - "A178857-", - "A178858-", - "T178859-", - "A178860-", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-", - "G178879-", - "T178880-", - "T178881-", - "A178882-", - "T178883-", - "G178884-", - "A178885-", - "A178886-", - "G178887-", - "C178888-", - "G178889-", - "T178890-", - "A178891-", - "T178892-", - "-196602A", - "-196603A" - ], - "OPG025": [ - "E385X", - "*631X" - ], - "OPG156": [ - "Q87R" - ] - }, - "labels": { - "aa": "OPG025: E385X, *631X; OPG156: Q87R" - } - } - }, - { - "name": "MpxV/Spain/MD-HGUGM-6532064/2022", - "node_attrs": { - "div": 67, - "author": { - "author": "Buenestado-Serrano,S., Palomino-Cabrera,R., Penas-Utrilla,D., Rodriguez-Grande,J., Sola Campoy,P., Perez-Lago,L., Rodriguez-Grande,C., Herranz Martin,M., Suarez,J., Catalan,P., Munoz,P., Garcia de Viedma,D.", - "value": "Buenestado-Serrano,S., Palomino-Cabrera,R., Penas-Utrilla,D., Rodriguez-Grande,J., Sola Campoy,P., Perez-Lago,L., Rodriguez-Grande,C., Herranz Martin,M., Suarez,J., Catalan,P., Munoz,P., Garcia de Viedma,D." - }, - "country": { - "value": "Spain" - }, - "date": { - "value": "2022-05-27" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Microbial Genomics, Hospital General Universitario Gregorio Marañón, Madrid, Spain" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/Spain/MD-HGUGM-6532064/2022" - }, - "strain": { - "value": "ON720849" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A322-", - "T596-", - "T597-", - "T598-", - "A1691-", - "A8048-", - "A9523-", - "C11747-", - "T15122-", - "T16095-", - "A19353-", - "A21075-", - "A27108-", - "A28524-", - "A28525-", - "A28596-", - "T32188-", - "A33193-", - "T34040-", - "T35565-", - "T37976-", - "T39127-", - "T39861-", - "T41738-", - "A43502-", - "T43503-", - "C43504T", - "T43505C", - "T46643-", - "A55119-", - "T56035-", - "A57274-", - "A58644-", - "A62034-", - "T64749-", - "A64931-", - "G69145-", - "A69739-", - "T76079-", - "T76080-", - "A76883-", - "A79177-", - "T79226-", - "A79457-", - "A79782-", - "T80841-", - "T88090-", - "T88831-", - "A89100-", - "A91698-", - "T94640-", - "T94789-", - "A98077-", - "T103362-", - "T105355-", - "T108710-", - "A110973-", - "T114514-", - "T114751-", - "A116008-", - "T116958-", - "T121116-", - "C122649T", - "A123988-", - "A124720-", - "A127246-", - "A127747-", - "A128927-", - "A132020-", - "A132021-", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "T133633-", - "T137881-", - "A138468-", - "A142462-", - "A144224-", - "A147994-", - "T148337-", - "T150532-", - "G150577-", - "A150578-", - "T150579-", - "A150580-", - "T150581-", - "G150582-", - "A150583-", - "T150584-", - "G150620-", - "G150621-", - "A150622-", - "T150623-", - "A150624-", - "T150625-", - "G150626-", - "A150627-", - "T150628-", - "A150629-", - "A151980-", - "A152668-", - "T152680-", - "A153418-", - "A154123-", - "T155417-", - "A157991-", - "T163592-", - "T168120-", - "A168956-", - "A170723-", - "T170897-", - "T172079-", - "T172661-", - "T178041-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A179945-", - "G181049-", - "A181246-", - "A182643-", - "T187073-", - "A190929-", - "T195513-", - "A196588-", - "A196604-", - "A196605-", - "A196606-", - "A196607-", - "T197177-" - ], - "NBT03_gp052": [ - "L8X", - "*130X" - ], - "NBT03_gp174": [ - "K174X", - "*177X" - ], - "OPG023": [ - "G385X", - "*661X" - ], - "OPG025": [ - "N49X", - "*631X" - ], - "OPG027": [ - "T95X", - "*151X" - ], - "OPG044": [ - "E145X", - "*150X" - ], - "OPG050": [ - "F72X", - "*76X" - ], - "OPG054": [ - "K144X", - "*440X" - ], - "OPG056": [ - "K353X", - "*636X" - ], - "OPG057": [ - "N112X", - "I357X", - "*373X" - ], - "OPG061": [ - "K49X", - "*232X" - ], - "OPG063": [ - "R62X", - "F63X", - "*480X" - ], - "OPG074": [ - "N364X", - "*666X" - ], - "OPG075": [ - "F75X", - "*109X" - ], - "OPG078": [ - "F56X", - "*74X" - ], - "OPG084": [ - "F10X", - "G70X", - "*677X" - ], - "OPG087": [ - "G97X", - "*221X" - ], - "OPG088": [ - "L42X", - "*125X" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG102": [ - "A31X", - "F48X", - "K125X", - "E233X", - "*334X" - ], - "OPG104": [ - "N60X", - "*134X" - ], - "OPG109": [ - "F116X", - "K206X", - "K453X", - "*796X" - ], - "OPG114": [ - "I10X", - "*147X" - ], - "OPG115": [ - "F44X", - "*234X" - ], - "OPG117": [ - "K677X", - "*786X" - ], - "OPG123": [ - "N570X", - "*632X" - ], - "OPG124": [ - "N205X", - "*288X" - ], - "OPG127": [ - "K39X", - "*225X" - ], - "OPG129": [ - "L11X", - "*645X" - ], - "OPG133": [ - "I316X", - "I395X", - "*711X" - ], - "OPG134": [ - "K87X", - "*293X" - ], - "OPG136": [ - "N877X", - "*892X" - ], - "OPG138": [ - "N6X", - "*191X" - ], - "OPG143": [ - "D223N" - ], - "OPG145": [ - "L14X", - "L258X", - "*493X" - ], - "OPG148": [ - "K421X", - "*427X" - ], - "OPG149": [ - "S17X", - "I184X", - "*188X" - ], - "OPG150": [ - "*383X" - ], - "OPG151": [ - "K2X", - "K1033X", - "*1165X" - ], - "OPG154": [ - "K57X", - "*111X" - ], - "OPG155": [ - "F8X", - "*147X" - ], - "OPG163": [ - "S87X", - "*177X" - ], - "OPG165": [ - "K237X", - "*269X" - ], - "OPG172": [ - "K190X", - "*197X" - ], - "OPG178": [ - "K158X", - "*205X" - ], - "OPG180": [ - "K243X", - "K478X", - "*560X" - ], - "OPG189": [ - "I87X", - "*562X" - ], - "OPG193": [ - "F263X", - "*268X" - ], - "OPG198": [ - "Q229X", - "*283X" - ], - "OPG208": [ - "E227X", - "*358X" - ], - "OPG209": [ - "G178X", - "*191X" - ], - "OPG210": [ - "K430X", - "*1881X" - ] - }, - "labels": { - "aa": "NBT03_gp052: L8X, *130X; NBT03_gp174: K174X, *177X; OPG023: G385X, *661X; OPG025: N49X, *631X; OPG027: T95X, *151X; OPG044: E145X, *150X; OPG050: F72X, *76X; OPG054: K144X, *440X; OPG056: K353X, *636X; OPG057: N112X, I357X, *373X; OPG061: K49X, *232X; OPG063: R62X, F63X, *480X; OPG074: N364X, *666X; OPG075: F75X, *109X; OPG078: F56X, *74X; OPG084: F10X, G70X, *677X; OPG087: G97X, *221X; OPG088: L42X, *125X; OPG097: K266X, *345X; OPG102: A31X, F48X, K125X, E233X, *334X; OPG104: N60X, *134X; OPG109: F116X, K206X, K453X, *796X; OPG114: I10X, *147X; OPG115: F44X, *234X; OPG117: K677X, *786X; OPG123: N570X, *632X; OPG124: N205X, *288X; OPG127: K39X, *225X; OPG129: L11X, *645X; OPG133: I316X, I395X, *711X; OPG134: K87X, *293X; OPG136: N877X, *892X; OPG138: N6X, *191X; OPG143: D223N; OPG145: L14X, L258X, *493X; OPG148: K421X, *427X; OPG149: S17X, I184X, *188X; OPG150: *383X; OPG151: K2X, K1033X, *1165X; OPG154: K57X, *111X; OPG155: F8X, *147X; OPG163: S87X, *177X; OPG165: K237X, *269X; OPG172: K190X, *197X; OPG178: K158X, *205X; OPG180: K243X, K478X, *560X; OPG189: I87X, *562X; OPG193: F263X, *268X; OPG198: Q229X, *283X; OPG208: E227X, *358X; OPG209: G178X, *191X; OPG210: K430X, *1881X" - } - } - }, - { - "name": "NODE_0000186", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G22643A", - "G63811A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-" - ], - "OPG038": [ - "H173Y" - ] - }, - "labels": { - "aa": "OPG038: H173Y" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_FL0018", - "node_attrs": { - "div": 66, - "author": { - "author": "Gigante,C.M., Lee,P., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Mendoza,R., Li,Y.", - "value": "Gigante,C.M., Lee,P., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Mendoza,R., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_FL0018" - }, - "strain": { - "value": "OP303781" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-" - ] - } - } - }, - { - "name": "MPXV_USA_2022_TX0011", - "node_attrs": { - "div": 66, - "author": { - "author": "Gigante,C.M., Kubin,G., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S.L., Li,Y.", - "value": "Gigante,C.M., Kubin,G., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S.L., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_TX0011" - }, - "strain": { - "value": "OP378705" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-" - ] - } - } - }, - { - "name": "ATL-UNIMOL-MPX-292895-L", - "node_attrs": { - "div": 66, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-08-12" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ATL-UNIMOL-MPX-292895-L" - }, - "strain": { - "value": "OP390176" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-086026/2022", - "node_attrs": { - "div": 69, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-086026/2022" - }, - "strain": { - "value": "OP442943" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G5375A", - "C155515T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "G186165A", - "T187073-", - "C191835T" - ], - "NBT03_gp175": [ - "A261V" - ], - "OPG015": [ - "A261V" - ], - "OPG210": [ - "D1604N" - ] - }, - "labels": { - "aa": "NBT03_gp175: A261V; OPG015: A261V; OPG210: D1604N" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-23267-O", - "node_attrs": { - "div": 66, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-08-23" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-23267-O" - }, - "strain": { - "value": "OP477454" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI497", - "node_attrs": { - "div": 68, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI497" - }, - "strain": { - "value": "OP626136" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C64635T", - "G141114A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG083": [ - "A28T" - ], - "OPG161": [ - "E5K" - ] - }, - "labels": { - "aa": "OPG083: A28T; OPG161: E5K" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-24722-L", - "node_attrs": { - "div": 67, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-09-08" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-24722-L" - }, - "strain": { - "value": "OP642374" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G168759A", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ], - "OPG195": [ - "R177K" - ] - }, - "labels": { - "aa": "OPG195: R177K" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI598", - "node_attrs": { - "div": 66, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI598" - }, - "strain": { - "value": "OP863248" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150565G", - "-150566A", - "-150567T", - "A178903-", - "T178904-", - "A178905-", - "C178906-", - "A178907-", - "T178908-", - "T178909-", - "T178910-", - "A178911-", - "A178912-", - "T178913-", - "G178914-", - "T178915-", - "G178916-", - "C178917-", - "T178918-", - "T178919-", - "A178920-", - "C178921-", - "G178922-", - "G178923-", - "A178924-", - "A178925-", - "C178926-", - "A178927-", - "T178928-", - "A178929-", - "T178930-", - "A178931-", - "T178932-", - "T178933-", - "T178934-", - "A178935-", - "G178936-", - "A178937-", - "A178938-", - "A178939-", - "C178940-", - "A178941-", - "T178942-", - "C178943-", - "T178944-", - "A178945-", - "C178946-", - "T178947-", - "A178948-", - "A178949-", - "C178950-", - "G178951-", - "A178952-", - "T178953-", - "T178954-", - "T178955-", - "T178956-", - "T178957-", - "T178958-", - "A178959-", - "T178960-", - "G178961-", - "C178962-", - "T178963-", - "T178964-", - "G178965-", - "T178966-", - "A178967-", - "T178968-", - "T178969-", - "A178970-", - "T178971-", - "T178972-", - "A178973-", - "A178974-", - "G181049-" - ], - "OPG209": [ - "G178X", - "*191X" - ] - }, - "labels": { - "aa": "OPG209: G178X, *191X" - } - } - }, - { - "name": "MPXV_USA_2022_FL0009", - "node_attrs": { - "div": 70, - "author": { - "author": "Gigante,C., Lee,P., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Stanek,D., Li,Y.", - "value": "Gigante,C., Lee,P., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Stanek,D., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-10-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_FL0009" - }, - "strain": { - "value": "OQ320513" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G4038A", - "A39081T", - "C67289T", - "G73790A", - "T133078-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "C193172T" - ], - "OPG057": [ - "I372N" - ], - "OPG085": [ - "E415K" - ], - "OPG094": [ - "G4E" - ] - }, - "labels": { - "aa": "OPG057: I372N; OPG085: E415K; OPG094: G4E" - } - } - }, - { - "name": "NY-NYCPHL-000786", - "node_attrs": { - "div": 67, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-12" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000786" - }, - "strain": { - "value": "OQ468798" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T122807A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG143": [ - "D170V" - ] - }, - "labels": { - "aa": "OPG143: D170V" - } - } - }, - { - "name": "NY-NYCPHL-000303", - "node_attrs": { - "div": 69, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-04" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000303" - }, - "strain": { - "value": "OQ469076" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C127215T", - "T133078-", - "T133079-", - "G169558A", - "C172154T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG149": [ - "S7L" - ], - "OPG200": [ - "T2M" - ] - }, - "labels": { - "aa": "OPG149: S7L; OPG200: T2M" - } - } - }, - { - "name": "MPXV_USA_2022_SC0010", - "node_attrs": { - "div": 68, - "author": { - "author": "Gigante,C., Epie,N., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Perez,T., Li,Y.", - "value": "Gigante,C., Epie,N., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Perez,T., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_SC0010" - }, - "strain": { - "value": "OQ721938" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C96649T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "G188382A" - ], - "OPG117": [ - "H201Y" - ] - }, - "labels": { - "aa": "OPG117: H201Y" - } - } - }, - { - "name": "NODE_0000187", - "node_attrs": { - "div": 67, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T119985C", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - }, - "children": [ - { - "name": "MPXV22/human/USA-NE-48", - "node_attrs": { - "div": 67, - "author": { - "author": "Tegomoh,B., Cross,S.T., Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., Pratt,C.B., Warden,D.E., Iwen,P.C., Donahue,M., Wiley,M.R.", - "value": "Tegomoh,B., Cross,S.T., Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., Pratt,C.B., Warden,D.E., Iwen,P.C., Donahue,M., Wiley,M.R." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-15" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV22/human/USA-NE-48" - }, - "strain": { - "value": "OP171923" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-196601A", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "MPX_imBNaw_9000300", - "node_attrs": { - "div": 68, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_imBNaw_9000300" - }, - "strain": { - "value": "OP415254" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G189258A" - ] - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-098497/2022", - "node_attrs": { - "div": 67, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-098497/2022" - }, - "strain": { - "value": "OP681775" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.8" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A136513-", - "T136514-", - "C136515-" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000188", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G74360A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179148T" - ], - "OPG094": [ - "R194H" - ] - }, - "labels": { - "aa": "OPG094: R194H", - "clade": "B.1.1" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI025", - "node_attrs": { - "div": 62, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI025" - }, - "strain": { - "value": "ON694329" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179148-", - "A192404-", - "G192405-", - "T192406-", - "C192407-", - "A192408-", - "T192409-", - "A192410-", - "A192411-", - "G192412-", - "T192413-", - "T192414-", - "A192415-", - "G192416-", - "T192417-", - "T192418-", - "A192419-", - "A192420-", - "G192421-", - "T192422-", - "C192423-", - "A192424-", - "T192425-", - "A192426-", - "A192427-", - "G192428-", - "T192429-", - "T192430-", - "A192431-", - "G192432-", - "T192433-", - "T192434-", - "A192435-", - "A192436-", - "G192437-", - "T192438-", - "C192439-", - "A192440-", - "T192441-", - "A192442-", - "A192443-", - "G192444-", - "T192445-", - "T192446-", - "A192447-", - "G192448-", - "T192449-", - "T192450-", - "A192451-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI023", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Stocker,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Stocker,H., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI023" - }, - "strain": { - "value": "ON694332" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A163211T", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179148-", - "A192404-", - "G192405-", - "T192406-", - "C192407-", - "A192408-", - "T192409-", - "A192410-", - "A192411-", - "G192412-", - "T192413-", - "T192414-", - "A192415-", - "G192416-", - "T192417-", - "T192418-", - "A192419-", - "A192420-", - "G192421-", - "T192422-", - "C192423-", - "A192424-", - "T192425-", - "A192426-", - "A192427-", - "G192428-", - "T192429-", - "T192430-", - "A192431-", - "G192432-", - "T192433-", - "T192434-", - "A192435-" - ] - } - } - }, - { - "name": "hMpxV/Switzerland/ZH-UZH-IMV-3ba6450e/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Kufner,V., Ziltener,G., Zaheri,M., Schmutz,S., Audige,A., Bernasconi,O., Steiner,K., Huder,J., Shah,C., Capaul,R., Bloemberg,G., Boeni,J., Huber,M., Trkola,A.", - "value": "Kufner,V., Ziltener,G., Zaheri,M., Schmutz,S., Audige,A., Bernasconi,O., Steiner,K., Huder,J., Shah,C., Capaul,R., Bloemberg,G., Boeni,J., Huber,M., Trkola,A." - }, - "country": { - "value": "Switzerland" - }, - "date": { - "value": "2022-06-02" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Zurich, Institute of Medical Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/Switzerland/ZH-UZH-IMV-3ba6450e/2022" - }, - "strain": { - "value": "ON792321" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T9151-", - "A9152-", - "T9153-", - "T9154-", - "T9155-", - "T9156-", - "A9157-", - "T9158-", - "A9159-", - "A9160-", - "T9161-", - "A9162-", - "A9163-", - "T9164-", - "G9165-", - "T19299-", - "A19300-", - "C19301-", - "T19302-", - "A19303-", - "A19304-", - "G43539-", - "T43540-", - "C43541-", - "T49124-", - "G49125-", - "A49126-", - "T49127-", - "G49128-", - "C49129-", - "A49130-", - "A49131-", - "A49132-", - "A49133-", - "A49134-", - "A49135-", - "C49136-", - "G49137-", - "A49138-", - "C49139-", - "G49140-", - "A49141-", - "T79020-", - "A79021-", - "T79022-", - "T79023-", - "A79024-", - "T79025-", - "A79026-", - "T79027-", - "T79028-", - "T79029-", - "T79030-", - "T79031-", - "T79032-", - "A79033-", - "T79034-", - "C79035-", - "T79036-", - "A79037-", - "A79038-", - "A79039-", - "A79040-", - "A79041-", - "A79042-", - "C79043-", - "T79044-", - "A79045-", - "A79046-", - "A79047-", - "A79048-", - "A79049-", - "T79050-", - "A79051-", - "A79052-", - "A79053-", - "C79054-", - "A79055-", - "T79056-", - "T79057-", - "G79058-", - "A79059-", - "T152633-", - "C152634-", - "T152635-", - "A152636-", - "A152637-", - "T152638-", - "G152639-", - "A152640-", - "C175864-", - "A175865-", - "T175866-", - "C175867-", - "T175868-", - "A175869-", - "G175870-", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127A", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136T", - "-179137A", - "-179138A", - "-179139T", - "-179140A", - "T179156-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "C179190T", - "A180392-", - "G180393-", - "T180394-", - "A180395-", - "T180396-", - "A180397-", - "G180398-" - ], - "OPG063": [ - "D50-" - ], - "OPG068": [ - "I308X", - "D309-", - "A310-", - "K311-", - "N312-", - "D313-", - "D314X", - "*568X" - ], - "OPG205": [ - "S70X", - "S71-", - "S72X", - "*788X" - ] - }, - "labels": { - "aa": "OPG063: D50-; OPG068: I308X, D309-, A310-, K311-, N312-, D313-, D314X, *568X; OPG205: S70X, S71-, S72X, *788X" - } - } - }, - { - "name": "MPXV-ROK-P1-2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Rhie,G.-E.", - "value": "Rhie,G.-E." - }, - "country": { - "value": "South Korea" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Korea Disease Control and Prevention Agency, Division of High-risk Pathogens" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV-ROK-P1-2022" - }, - "strain": { - "value": "OP204857" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C786T", - "C71728T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G173429A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179147T" - ], - "OPG091": [ - "A120V" - ] - }, - "labels": { - "aa": "OPG091: A120V" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI208", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI208" - }, - "strain": { - "value": "OP215245" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "G176536A", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179148-" - ], - "OPG205": [ - "R294K" - ] - }, - "labels": { - "aa": "OPG205: R294K" - } - } - }, - { - "name": "hMPXV-IHU00002", - "node_attrs": { - "div": 62, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "country": { - "value": "France" - }, - "date": { - "value": "2022-07-01" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPXV-IHU00002" - }, - "strain": { - "value": "OP382479" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179147T" - ] - } - } - }, - { - "name": "hMPXV-IHU00011", - "node_attrs": { - "div": 63, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "country": { - "value": "France" - }, - "date": { - "value": "2022-07-19" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPXV-IHU00011" - }, - "strain": { - "value": "OP382488" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "-595T", - "C153387T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179147T", - "A196599-", - "C196600-", - "-196602A" - ] - } - } - }, - { - "name": "Monkeypox/PT0564/2022", - "node_attrs": { - "div": 67, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-09-05" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0564/2022" - }, - "strain": { - "value": "OP555635" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C23422T", - "G54619A", - "G68997A", - "C69705T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C156100T", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179148-" - ], - "OPG039": [ - "E233K" - ] - }, - "labels": { - "aa": "OPG039: E233K" - } - } - }, - { - "name": "MPXV_USA_2022_IN0006", - "node_attrs": { - "div": 65, - "author": { - "author": "Gigante,C., Culbertson,M., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Weigand,M., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Pope,B., Li,Y.", - "value": "Gigante,C., Culbertson,M., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Weigand,M., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Pope,B., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_IN0006" - }, - "strain": { - "value": "OQ320518" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T22135C", - "G52232A", - "C119838T", - "A136513-", - "T136514-", - "C136515-" - ], - "OPG037": [ - "H100R" - ], - "OPG071": [ - "S736L" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG037: H100R; OPG071: S736L; OPG153: D385-" - } - } - }, - { - "name": "NY-NYCPHL-001012", - "node_attrs": { - "div": 65, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-07" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-001012" - }, - "strain": { - "value": "OQ469217" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G27077A", - "G94798A", - "C134504T", - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179147T" - ], - "OPG115": [ - "E47K" - ] - }, - "labels": { - "aa": "OPG115: E47K" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI850", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI850" - }, - "strain": { - "value": "OQ773469" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G7315A", - "G150550-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179148-" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_218/Belgium/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-08-08" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_218/Belgium/2022" - }, - "strain": { - "value": "OR095036" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C25828T", - "G107496A", - "G109463A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179147T" - ], - "OPG042": [ - "E424K" - ] - }, - "labels": { - "aa": "OPG042: E424K" - } - } - }, - { - "name": "MPXV_USA_2022_NE0006", - "node_attrs": { - "div": 65, - "author": { - "author": "Li,C.M.", - "value": "Li,C.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_NE0006" - }, - "strain": { - "value": "OR209326" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G11924A", - "G34800A", - "T133078-", - "A136513-", - "T136514-", - "C136515-", - "G160406A", - "-179140A", - "-179147T" - ], - "OPG023": [ - "S326L" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG023: S326L; OPG153: D385-" - } - } - }, - { - "name": "NODE_0000189", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C11401T", - "T133078-", - "A136513-", - "T136514-", - "C136515-", - "-179140A", - "-179147T" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_MT0002", - "node_attrs": { - "div": 63, - "author": { - "author": "Gigante,C., Mozer,M., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Hopkins,B., Li,Y.", - "value": "Gigante,C., Mozer,M., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Hopkins,B., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_MT0002" - }, - "strain": { - "value": "OQ320460" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133079-" - ] - } - } - }, - { - "name": "MPXV_USA_2022_NV0005", - "node_attrs": { - "div": 65, - "author": { - "author": "Gigante,C., Buttery,E., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Knipe,K., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Raman,D., Li,Y.", - "value": "Gigante,C., Buttery,E., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Knipe,K., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Raman,D., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-10-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_NV0005" - }, - "strain": { - "value": "OQ427112" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C72269T", - "G140194A", - "G158318A" - ], - "OPG092": [ - "D227N" - ], - "OPG159": [ - "D143N" - ], - "OPG160": [ - "S294L" - ] - }, - "labels": { - "aa": "OPG092: D227N; OPG159: D143N; OPG160: S294L" - } - } - }, - { - "name": "MPXV_USA_2022_TX0051", - "node_attrs": { - "div": 65, - "author": { - "author": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y.", - "value": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_TX0051" - }, - "strain": { - "value": "OQ721942" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G23673A", - "G50121A", - "-133078T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T" - ], - "OPG039": [ - "S149L" - ], - "OPG069": [ - "E46K" - ] - }, - "labels": { - "aa": "OPG039: S149L; OPG069: E46K" - } - } - } - ] - }, - { - "name": "NODE_0000190", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "G155698A" - ] - } - }, - "children": [ - { - "name": "Monkeypox/PT0592/2022", - "node_attrs": { - "div": 68, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-09-14" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0592/2022" - }, - "strain": { - "value": "OP555659" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C21910T", - "C67207T", - "G81244A", - "G109451A", - "-133078T", - "G138237A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179148-", - "A196524-", - "C196525-" - ], - "OPG037": [ - "R175K" - ], - "OPG085": [ - "R442K" - ], - "OPG105": [ - "R40K" - ] - }, - "labels": { - "aa": "OPG037: R175K; OPG085: R442K; OPG105: R40K" - } - } - }, - { - "name": "MPXV/UZ_REGA_180/Belgium/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-07-27" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_180/Belgium/2022" - }, - "strain": { - "value": "OR086989" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C7037T", - "G10930A", - "C109896T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179147T" - ], - "OPG129": [ - "R370K" - ] - }, - "labels": { - "aa": "OPG129: R370K" - } - } - }, - { - "name": "NODE_0000191", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G161575A", - "-196603A" - ] - } - }, - "children": [ - { - "name": "Monkeypox/PT0586/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-05" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0586/2022" - }, - "strain": { - "value": "OP555655" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C54306T", - "-133078T", - "C167451T", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179148-" - ], - "OPG071": [ - "E45K" - ] - }, - "labels": { - "aa": "OPG071: E45K" - } - } - }, - { - "name": "MPXV/UZ_REGA_133/Belgium/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-07-05" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_133/Belgium/2022" - }, - "strain": { - "value": "OR086942" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T149487-", - "A149488-", - "C149489-", - "G149490-", - "T149491-", - "T149492-", - "G149493-", - "A149494-", - "A149495-", - "C149496-", - "A149497-", - "A149498-", - "G149499-", - "T149500-", - "C149501-", - "C149502-", - "A149503-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179147T", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG175": [ - "Y16-", - "V17-", - "E18-", - "Q19-", - "V20-", - "H21X", - "*126X" - ] - }, - "labels": { - "aa": "OPG175: Y16-, V17-, E18-, Q19-, V20-, H21X, *126X" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000192", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C22739T" - ], - "OPG038": [ - "E141K" - ] - }, - "labels": { - "aa": "OPG038: E141K" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI01", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI01" - }, - "strain": { - "value": "ON637938" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C169722-", - "A169723-", - "G169724-", - "A169725-", - "T169726-", - "A169727-", - "C169728-", - "A169729-", - "G169730-", - "A169731-", - "T169732-", - "A169733-", - "C169734-", - "A169735-", - "G169736-", - "A169737-", - "T169738-", - "A169739-", - "C169740-", - "A169741-", - "G169742-", - "A169743-", - "T169744-", - "A169745-", - "C169746-", - "A169747-", - "G169748-", - "A169749-", - "T169750-", - "A169751-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-" - ], - "OPG197": [ - "S18X", - "D19-", - "T20-", - "D21-", - "T22-", - "D23-", - "T24-", - "D25-", - "T26-", - "D27-", - "T28X", - "*101X" - ] - }, - "labels": { - "aa": "OPG197: S18X, D19-, T20-, D21-, T22-, D23-, T24-, D25-, T26-, D27-, T28X, *101X" - } - } - }, - { - "name": "CVR_MPXV1a", - "node_attrs": { - "div": 63, - "author": { - "author": "Filipe,A., Tong,L., Vattipally,S.B., Maclean,A., Gunson,R., Holden,M.T.G., Barr,D., Ho,A., Palmarini,M., Rambaut,A., Robertson,D.L., Thomson,E.C.", - "value": "Filipe,A., Tong,L., Vattipally,S.B., Maclean,A., Gunson,R., Holden,M.T.G., Barr,D., Ho,A., Palmarini,M., Rambaut,A., Robertson,D.L., Thomson,E.C." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-05-15" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "CVR_MPXV1a" - }, - "strain": { - "value": "ON808413" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133098-", - "T133099-", - "T133100-", - "T133101-", - "T133102-", - "C133103-", - "A136513-", - "T136514-", - "C136515-", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179147T" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI051", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Pfaefflin,F., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Pfaefflin,F., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI051" - }, - "strain": { - "value": "ON813251" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T178987-", - "G178988-", - "A178989-", - "T178990-", - "T178991-", - "T178992-", - "A178993-", - "A178994-", - "T178995-", - "T178996-", - "G178997-", - "A178998-", - "T178999-", - "T179000-", - "G179001-", - "T179002-", - "G179003-", - "T179004-", - "A179005-", - "C179006-", - "A179007-", - "C179008-", - "G179009-", - "A179010-", - "T179011-", - "A179012-", - "C179013-", - "C179014-", - "A179015-", - "A179016-", - "T179017-", - "T179018-", - "T179019-", - "G179020-", - "T179021-", - "C179022-", - "G179023-", - "A179024-", - "G179025-", - "T179026-", - "A179027-", - "T179028-", - "G179029-", - "A179030-", - "A179031-", - "T179032-", - "A179033-", - "C179034-", - "G179035-", - "G179036-", - "A179037-", - "G179038-", - "T179039-", - "A179040-", - "C179041-", - "A179042-", - "A179043-", - "A179044-", - "C179045-", - "A179046-", - "T179047-", - "A179048-", - "A179049-", - "A179050-", - "C179051-", - "T179052-", - "G179053-", - "A179054-", - "A179055-", - "G179056-", - "T179057-", - "T179058-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI088", - "node_attrs": { - "div": 67, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI088" - }, - "strain": { - "value": "ON853655" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G21655A", - "G63811A", - "G63892A", - "G135221A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179148-" - ], - "OPG037": [ - "S260L" - ] - }, - "labels": { - "aa": "OPG037: S260L" - } - } - }, - { - "name": "hMPXV/Austria/MUW1527495/2022", - "node_attrs": { - "div": 63, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "country": { - "value": "Austria" - }, - "date": { - "value": "2022-06-21" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1527495/2022" - }, - "strain": { - "value": "OP019276" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179147T" - ] - } - } - }, - { - "name": "MPXV_UK_2022_9000179", - "node_attrs": { - "div": 63, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-06-26" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000179" - }, - "strain": { - "value": "OP205128" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179147T" - ] - } - } - }, - { - "name": "MPXV_USA_2022_NY0013", - "node_attrs": { - "div": 65, - "author": { - "author": "Gigante,C.M., Hughes,S., Seabolt,M.H., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Baumgartner,J., Li,Y.", - "value": "Gigante,C.M., Hughes,S., Seabolt,M.H., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Baumgartner,J., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_NY0013" - }, - "strain": { - "value": "OP225960" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C113660T", - "C163459T", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-" - ], - "OPG133": [ - "M679I" - ], - "OPG189": [ - "R43*" - ] - }, - "labels": { - "aa": "OPG133: M679I; OPG189: R43*" - } - } - }, - { - "name": "MPX_dDDHx_9000207", - "node_attrs": { - "div": 64, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_dDDHx_9000207" - }, - "strain": { - "value": "OP415188" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A33221-", - "T33222-", - "A33223-", - "T33224-", - "T33225-", - "C33226-", - "T33227-", - "C33228-", - "A33229-", - "T33230-", - "T33231-", - "G33232-", - "C33233-", - "T33234-", - "C144199T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179147T" - ], - "OPG050": [ - "S59-", - "N60-", - "E61-", - "N62-", - "I63X", - "*76X" - ] - }, - "labels": { - "aa": "OPG050: S59-, N60-, E61-, N62-, I63X, *76X" - } - } - }, - { - "name": "MPX_XAF7gk_9000317", - "node_attrs": { - "div": 64, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_XAF7gk_9000317" - }, - "strain": { - "value": "OP415258" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C172730T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179147T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI400", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI400" - }, - "strain": { - "value": "OP524005" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179148-" - ] - } - } - }, - { - "name": "MPXV_USA_2022_AK0002", - "node_attrs": { - "div": 68, - "author": { - "author": "Gigante,C., Mooring,E., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Laurence,J., Li,Y.", - "value": "Gigante,C., Mooring,E., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Laurence,J., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_AK0002" - }, - "strain": { - "value": "OQ054242" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6234A", - "G45914A", - "G121553A", - "A151485-", - "C186124T", - "C189996T", - "C190976T" - ], - "OPG140": [ - "S65F" - ], - "OPG210": [ - "S1590F" - ] - }, - "labels": { - "aa": "OPG140: S65F; OPG210: S1590F" - } - } - }, - { - "name": "NY-NYCPHL-000083", - "node_attrs": { - "div": 63, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-16" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000083" - }, - "strain": { - "value": "OQ504391" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179147T" - ] - } - } - }, - { - "name": "NODE_0000193", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150567T", - "G173727A", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179148-" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI366", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI366" - }, - "strain": { - "value": "OP484687" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A" - ] - } - } - }, - { - "name": "NODE_0000194", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G55993A", - "G150550-" - ], - "OPG074": [ - "S378F" - ] - }, - "labels": { - "aa": "OPG074: S378F" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/ON/RKI748", - "node_attrs": { - "div": 66, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI748" - }, - "strain": { - "value": "OQ547775" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C129096T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ], - "OPG151": [ - "S58L" - ] - }, - "labels": { - "aa": "OPG151: S58L" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI828", - "node_attrs": { - "div": 65, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI828" - }, - "strain": { - "value": "OQ773447" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000195", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C22740T", - "C38937T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179148-" - ], - "OPG056": [ - "R33Q" - ] - }, - "labels": { - "aa": "OPG056: R33Q" - } - }, - "children": [ - { - "name": "MPX/PT0114/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-07-15" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX/PT0114/2022" - }, - "strain": { - "value": "OP245348" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPX_KV9qz9_9000349", - "node_attrs": { - "div": 66, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_KV9qz9_9000349" - }, - "strain": { - "value": "OP415276" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C67659T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG085": [ - "M291I" - ] - }, - "labels": { - "aa": "OPG085: M291I" - } - } - }, - { - "name": "Monkeypox/PT0400/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-07-19" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0400/2022" - }, - "strain": { - "value": "OP555496" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G174240A" - ] - } - } - }, - { - "name": "Monkeypox/PT0556/2022", - "node_attrs": { - "div": 68, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-30" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0556/2022" - }, - "strain": { - "value": "OP555627" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G74362A", - "A136537-", - "T136538-", - "C136539-", - "A136540-", - "T136541-", - "C136542-", - "A136543-", - "T136544-", - "C136545-", - "A136546-", - "T136547-", - "C136548-", - "A136549-", - "T136550-", - "C136551-", - "A136552-", - "T136553-", - "C136554-", - "T136555-", - "A136556-", - "T136557-", - "G136558-", - "A136559-", - "T136560-", - "G157775A", - "C177240T", - "-196603A" - ], - "OPG094": [ - "A195T" - ], - "OPG153": [ - "I370-", - "I371-", - "D372-", - "D373-", - "D374-", - "D375-", - "D376-", - "D377-" - ], - "OPG205": [ - "Q529*" - ] - }, - "labels": { - "aa": "OPG094: A195T; OPG153: I370-, I371-, D372-, D373-, D374-, D375-, D376-, D377-; OPG205: Q529*" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000212", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C70780T", - "-150565G", - "-150567T" - ] - }, - "labels": { - "clade": "B.1.5" - } - }, - "children": [ - { - "name": "hMpxV/Switzerland/ZH-UZH-IMV-3ba64538/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Kufner,V., Ziltener,G., Zaheri,M., Schmutz,S., Audige,A., Bernasconi,O., Steiner,K., Huder,J., Shah,C., Capaul,R., Bloemberg,G., Boeni,J., Huber,M., Trkola,A.", - "value": "Kufner,V., Ziltener,G., Zaheri,M., Schmutz,S., Audige,A., Bernasconi,O., Steiner,K., Huder,J., Shah,C., Capaul,R., Bloemberg,G., Boeni,J., Huber,M., Trkola,A." - }, - "country": { - "value": "Switzerland" - }, - "date": { - "value": "2022-06-02" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Zurich, Institute of Medical Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/Switzerland/ZH-UZH-IMV-3ba64538/2022" - }, - "strain": { - "value": "ON792322" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150565-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/human/Taiwan/110-231642/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "country": { - "value": "Taiwan" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/human/Taiwan/110-231642/2022" - }, - "strain": { - "value": "ON918656" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C28702T", - "T34793C", - "T50861C", - "C51777T", - "G150565-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG054": [ - "T402A" - ], - "OPG070": [ - "V91A" - ], - "OPG071": [ - "E888K" - ] - }, - "labels": { - "aa": "OPG054: T402A; OPG070: V91A; OPG071: E888K" - } - } - }, - { - "name": "MPXV_USA_2022_GA001", - "node_attrs": { - "div": 62, - "author": { - "author": "Gigante,C., Xia,D., Seabolt,M., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Plipat,N., Li,Y.", - "value": "Gigante,C., Xia,D., Seabolt,M., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Plipat,N., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_GA001" - }, - "strain": { - "value": "OP150925" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150565-", - "T150567-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI331", - "node_attrs": { - "div": 67, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI331" - }, - "strain": { - "value": "OP373389" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G43756A", - "C69494T", - "C89921T", - "G135954A", - "G144572A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A" - ], - "OPG087": [ - "S213L" - ], - "OPG088": [ - "E124K" - ], - "OPG110": [ - "S97L" - ] - }, - "labels": { - "aa": "OPG087: S213L; OPG088: E124K; OPG110: S97L" - } - } - }, - { - "name": "Monkeypox/PT0244/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-06-21" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0244/2022" - }, - "strain": { - "value": "OP414288" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-196603A" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI466", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI466" - }, - "strain": { - "value": "OP626104" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G61213A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A" - ], - "OPG080": [ - "S269L" - ] - }, - "labels": { - "aa": "OPG080: S269L" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI663", - "node_attrs": { - "div": 62, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI663" - }, - "strain": { - "value": "OQ274882" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150565-", - "T150567-", - "A152668-", - "T152680-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI406", - "node_attrs": { - "div": 62, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI406" - }, - "strain": { - "value": "OP524008" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A" - ] - } - } - }, - { - "name": "Monkeypox/PT0033/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-05-24" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0033/2022" - }, - "strain": { - "value": "ON843165" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI485", - "node_attrs": { - "div": 62, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI485" - }, - "strain": { - "value": "OP626123" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A" - ] - } - } - }, - { - "name": "INMI-Pt4", - "node_attrs": { - "div": 62, - "author": { - "author": "Gramigna,G., Giombini,E., Gruber,C.E.M., Rueca,M., Carletti,F., Cicalini,S., Lapa,D., Puro,V., Marani,A., Fabeni,L., Butera,O., Colavita,F., Meschi,S., Matusali,G., Rivano Capparuccia,M., Specchiarello,E., Vairo,F., Vaia,F., Nicastri,E., Antinori,A., Girardi,E., Maggi,F.", - "value": "Gramigna,G., Giombini,E., Gruber,C.E.M., Rueca,M., Carletti,F., Cicalini,S., Lapa,D., Puro,V., Marani,A., Fabeni,L., Butera,O., Colavita,F., Meschi,S., Matusali,G., Rivano Capparuccia,M., Specchiarello,E., Vairo,F., Vaia,F., Nicastri,E., Antinori,A., Girardi,E., Maggi,F." - }, - "country": { - "value": "Italy" - }, - "date": { - "value": "2022-05-21" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "INMI-Pt4" - }, - "strain": { - "value": "ON780017" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150565-", - "T150567-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI162", - "node_attrs": { - "div": 62, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI162" - }, - "strain": { - "value": "ON959175" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI300", - "node_attrs": { - "div": 62, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI300" - }, - "strain": { - "value": "OP355562" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "A188349-" - ] - } - } - }, - { - "name": "hMPXV-CH-38347314/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Laubscher,F., Marques-Melancia,S., Cordey,S., Schibler,M., Kaiser,L., Renzoni,A.", - "value": "Laubscher,F., Marques-Melancia,S., Cordey,S., Schibler,M., Kaiser,L., Renzoni,A." - }, - "country": { - "value": "Switzerland" - }, - "date": { - "value": "2022-06-08" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University Hospitals of Geneva, Laboratory of Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMPXV-CH-38347314/2022" - }, - "strain": { - "value": "OP783902" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150565-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI638", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI638" - }, - "strain": { - "value": "OQ159033" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G147459A", - "G150565-", - "T150567-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI665", - "node_attrs": { - "div": 62, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI665" - }, - "strain": { - "value": "OQ274884" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150566A", - "A152668-", - "T152680-" - ] - } - } - }, - { - "name": "NODE_0000095", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A550-", - "T551-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "G159001A", - "C196435-", - "G196436-" - ], - "OPG185": [ - "D29N" - ] - }, - "labels": { - "aa": "OPG185: D29N" - } - }, - "children": [ - { - "name": "MPX/PT0090/2022", - "node_attrs": { - "div": 63, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-07-21" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX/PT0090/2022" - }, - "strain": { - "value": "OP245340" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0579/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-09-10" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0579/2022" - }, - "strain": { - "value": "OP555650" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C41022T", - "A136513-", - "T136514-", - "C136515-" - ], - "OPG060": [ - "R54K" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG060: R54K; OPG153: D385-" - } - } - } - ] - }, - { - "name": "NODE_0000123", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C133867T", - "C134247T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A" - ] - } - }, - "children": [ - { - "name": "Monkeypox/PT0471/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-08" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0471/2022" - }, - "strain": { - "value": "OP555550" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G58545A", - "A126737G" - ], - "OPG148": [ - "D251G" - ] - }, - "labels": { - "aa": "OPG148: D251G" - } - } - }, - { - "name": "Monkeypox/PT0527/2022", - "node_attrs": { - "div": 70, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-19" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0527/2022" - }, - "strain": { - "value": "OP555598" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G5876A", - "C87141T", - "C126707T", - "C128030T", - "C128417T", - "C187128T", - "C191334T" - ], - "NBT03_gp175": [ - "S94F" - ], - "OPG015": [ - "S94F" - ], - "OPG148": [ - "S241L" - ] - }, - "labels": { - "aa": "NBT03_gp175: S94F; OPG015: S94F; OPG148: S241L" - } - } - } - ] - }, - { - "name": "NODE_0000098", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C25644T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI140", - "node_attrs": { - "div": 65, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI140" - }, - "strain": { - "value": "ON959149" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G156469A", - "C190668T" - ], - "NBT03_gp174": [ - "R87*" - ] - }, - "labels": { - "aa": "NBT03_gp174: R87*" - } - } - }, - { - "name": "Monkeypox/PT0135/2022", - "node_attrs": { - "div": 63, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-07-08" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0135/2022" - }, - "strain": { - "value": "OP324458" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-196603A" - ] - } - } - }, - { - "name": "NODE_0000099", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G63147A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - }, - "children": [ - { - "name": "MPXV_UK_2022_9000106", - "node_attrs": { - "div": 64, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-06-14" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000106" - }, - "strain": { - "value": "OP205094" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "9000289", - "node_attrs": { - "div": 64, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000289" - }, - "strain": { - "value": "OP413714" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T16609-", - "C16610-", - "A16611-" - ], - "OPG029": [ - "D153X", - "D154X", - "*156X" - ] - }, - "labels": { - "aa": "OPG029: D153X, D154X, *156X" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000124", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C44333T", - "G150565-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG064": [ - "M522I" - ] - }, - "labels": { - "aa": "OPG064: M522I" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI085", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI085" - }, - "strain": { - "value": "ON853667" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G46956A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ], - "OPG066": [ - "P158L" - ] - }, - "labels": { - "aa": "OPG066: P158L" - } - } - }, - { - "name": "MPX_luLfgA_9000208", - "node_attrs": { - "div": 63, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_luLfgA_9000208" - }, - "strain": { - "value": "OP415189" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/UZ_REGA_69", - "node_attrs": { - "div": 64, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-06-30" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_69" - }, - "strain": { - "value": "OR035675" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G161488A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_96", - "node_attrs": { - "div": 67, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-05-30" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_96" - }, - "strain": { - "value": "OR035702" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C29315T", - "C60396T", - "G149807A", - "C161572T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG046": [ - "D139N" - ] - }, - "labels": { - "aa": "OPG046: D139N" - } - } - }, - { - "name": "NODE_0000125", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G93512T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG113": [ - "K594N" - ] - }, - "labels": { - "aa": "OPG113: K594N" - } - }, - "children": [ - { - "name": "SIC-AOUP-UNIPA_VL_9aug", - "node_attrs": { - "div": 67, - "author": { - "author": "Tramuto,F.", - "value": "Tramuto,F." - }, - "country": { - "value": "Italy" - }, - "date": { - "value": "2022-08-09" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Palermo, Department of Health Promotion Sciences Maternal and Infant Care, Internal Medicine and Medical Specialties \"G. D'Alessandro\"" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "SIC-AOUP-UNIPA_VL_9aug" - }, - "strain": { - "value": "OP358276" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C33103T", - "C114490T", - "C133295T", - "T179026-", - "A179027-", - "T179028-", - "G179029-", - "A179030-", - "A179031-", - "T179032-", - "A179033-", - "C179034-", - "G179035-", - "G179036-", - "A179037-", - "G179038-", - "T179039-", - "A179040-", - "C179041-", - "A179042-", - "A179043-" - ], - "OPG049": [ - "E17K" - ], - "OPG133": [ - "D403N" - ] - }, - "labels": { - "aa": "OPG049: E17K; OPG133: D403N" - } - } - }, - { - "name": "9000394", - "node_attrs": { - "div": 66, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000394" - }, - "strain": { - "value": "OP536772" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C756T", - "G2898A", - "G3477A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C193733T", - "C194312T", - "G196454A" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000126", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150565-", - "C160426T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - }, - "children": [ - { - "name": "NODE_0000127", - "node_attrs": { - "div": 67, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A10432-", - "T10433-", - "T10434-", - "A10435-", - "G10436-", - "G75332A", - "T124690C", - "C144211T", - "T150567-", - "G185394A" - ], - "OPG095": [ - "R177K" - ], - "OPG210": [ - "E1347K" - ] - }, - "labels": { - "aa": "OPG095: R177K; OPG210: E1347K" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-119069/2022", - "node_attrs": { - "div": 67, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-11-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-119069/2022" - }, - "strain": { - "value": "OQ503754" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/USA/WA-UW-113327/2022", - "node_attrs": { - "div": 68, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-11-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-113327/2022" - }, - "strain": { - "value": "OQ503755" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C135762T" - ] - } - } - } - ] - }, - { - "name": "NODE_0000128", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G111379A", - "-150559G", - "G165326A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG130": [ - "S175L" - ], - "OPG190": [ - "E69K" - ] - }, - "labels": { - "aa": "OPG130: S175L; OPG190: E69K" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_NY0025", - "node_attrs": { - "div": 65, - "author": { - "author": "Gigante,C., Ruiz,V., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Wang,J., Li,Y.", - "value": "Gigante,C., Ruiz,V., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Wang,J., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_NY0025" - }, - "strain": { - "value": "OQ320464" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150559-", - "T150567-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-" - ] - } - } - }, - { - "name": "NY-NYCPHL-000785", - "node_attrs": { - "div": 65, - "author": { - "author": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-08" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000785" - }, - "strain": { - "value": "OQ468661" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A" - ] - } - } - }, - { - "name": "NY-NYCPHL-000617", - "node_attrs": { - "div": 65, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-10" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000617" - }, - "strain": { - "value": "OQ468715" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "G150559-" - ] - } - } - }, - { - "name": "NY-NYCPHL-000192", - "node_attrs": { - "div": 65, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-30" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000192" - }, - "strain": { - "value": "OQ468827" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150565G", - "-150566A" - ] - } - } - }, - { - "name": "NY-NYCPHL-000132", - "node_attrs": { - "div": 65, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-26" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000132" - }, - "strain": { - "value": "OQ469143" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A" - ] - } - } - }, - { - "name": "NY-NYCPHL-000542", - "node_attrs": { - "div": 65, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-23" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000542" - }, - "strain": { - "value": "OQ504461" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T" - ] - } - } - }, - { - "name": "NODE_0000129", - "node_attrs": { - "div": 70, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G74391A", - "G98473A", - "C124495T", - "C132962T", - "C149264T", - "G150559-", - "T150567-", - "-196603A" - ], - "OPG094": [ - "M204I" - ], - "OPG118": [ - "D10N" - ] - }, - "labels": { - "aa": "OPG094: M204I; OPG118: D10N" - } - }, - "children": [ - { - "name": "NY-NYCPHL-000425", - "node_attrs": { - "div": 70, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-12" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000425" - }, - "strain": { - "value": "OQ504436" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV_USA_2022_NY0046", - "node_attrs": { - "div": 70, - "author": { - "author": "Gigante,C., Ruiz,V., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Wang,J., Li,Y.", - "value": "Gigante,C., Ruiz,V., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Wang,J., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_NY0046" - }, - "strain": { - "value": "OQ721932" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.5" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-" - ] - } - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000196", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G186165A" - ], - "OPG210": [ - "D1604N" - ] - }, - "labels": { - "aa": "OPG210: D1604N", - "clade": "B.1.2" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI124", - "node_attrs": { - "div": 62, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI124" - }, - "strain": { - "value": "ON929079" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI673", - "node_attrs": { - "div": 62, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI673" - }, - "strain": { - "value": "OQ274892" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A152668-", - "T152680-" - ] - } - } - }, - { - "name": "NODE_0000197", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G92048A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - }, - "children": [ - { - "name": "MPXV_UK_2022_9000186", - "node_attrs": { - "div": 63, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-06-29" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000186" - }, - "strain": { - "value": "OP205131" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000198", - "node_attrs": { - "div": 72, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T11371C", - "G34303A", - "C85322T", - "G123119A", - "G129583A", - "C140931T", - "C153104T", - "C178378T", - "C188391T" - ], - "OPG053": [ - "P130S" - ], - "OPG143": [ - "S66L" - ], - "OPG180": [ - "S138F" - ] - }, - "labels": { - "aa": "OPG053: P130S; OPG143: S66L; OPG180: S138F" - } - }, - "children": [ - { - "name": "9000231", - "node_attrs": { - "div": 72, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000231" - }, - "strain": { - "value": "OP413713" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPX_TcUINH_9000230", - "node_attrs": { - "div": 72, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_TcUINH_9000230" - }, - "strain": { - "value": "OP415205" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000199", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150566A", - "-150567T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "C188391T" - ] - } - }, - "children": [ - { - "name": "MPXV_UK_2022_9000092", - "node_attrs": { - "div": 63, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-05-25" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000092" - }, - "strain": { - "value": "OP205083" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150566-", - "T150567-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI228", - "node_attrs": { - "div": 65, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI228" - }, - "strain": { - "value": "OP215256" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C22880T", - "G62253A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150563A", - "-150564T", - "-150565G", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ], - "OPG038": [ - "E94K" - ] - }, - "labels": { - "aa": "OPG038: E94K" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI238", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI238" - }, - "strain": { - "value": "OP215262" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150563A", - "-150564T", - "-150565G", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "G182303A" - ] - } - } - }, - { - "name": "9000369", - "node_attrs": { - "div": 64, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000369" - }, - "strain": { - "value": "OP536750" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150563A", - "-150564T", - "-150565G", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "C188491T", - "T190786-", - "T190787-" - ], - "NBT03_gp174": [ - "I126X", - "*177X" - ] - }, - "labels": { - "aa": "NBT03_gp174: I126X, *177X" - } - } - }, - { - "name": "9000408", - "node_attrs": { - "div": 63, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000408" - }, - "strain": { - "value": "OP536784" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150563A", - "-150564T", - "-150565G", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - }, - { - "name": "9000416", - "node_attrs": { - "div": 63, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000416" - }, - "strain": { - "value": "OP536790" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150563A", - "-150564T", - "-150565G", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "A196604-" - ] - } - } - }, - { - "name": "Slovenia-MPXV-42-2022", - "node_attrs": { - "div": 68, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "country": { - "value": "Slovenia" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Slovenia-MPXV-42-2022" - }, - "strain": { - "value": "OP605583" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A138-", - "-595T", - "C17614A", - "C27187T", - "G111484A", - "G147305A", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150566-", - "T150567-", - "C159401A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG030": [ - "V74L" - ], - "OPG043": [ - "D257N" - ], - "OPG130": [ - "T140I" - ], - "OPG185": [ - "S162Y" - ] - }, - "labels": { - "aa": "OPG030: V74L; OPG043: D257N; OPG130: T140I; OPG185: S162Y" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI461", - "node_attrs": { - "div": 65, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI461" - }, - "strain": { - "value": "OP615335" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6771A", - "C99166T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150563A", - "-150564T", - "-150565G", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ] - } - } - }, - { - "name": "hMpxV/USA/CA-CDPH-1MPX1000112/2022", - "node_attrs": { - "div": 72, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-12-14" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/USA/CA-CDPH-1MPX1000112/2022" - }, - "strain": { - "value": "OQ348860" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C7705T", - "C39334G", - "G50617A", - "G62896A", - "G89947A", - "C110394T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150563A", - "-150564T", - "-150565G", - "G150753A", - "A158920T", - "G183899A" - ], - "OPG057": [ - "A288P" - ], - "OPG070": [ - "D10N" - ], - "OPG082": [ - "S186L" - ], - "OPG110": [ - "E106K" - ], - "OPG129": [ - "R204Q" - ], - "OPG185": [ - "T2S" - ] - }, - "labels": { - "aa": "OPG057: A288P; OPG070: D10N; OPG082: S186L; OPG110: E106K; OPG129: R204Q; OPG185: T2S" - } - } - }, - { - "name": "MPXV_USA_2022_TN0015", - "node_attrs": { - "div": 65, - "author": { - "author": "Gigante,C., Thomas,L., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Dunn,J., Li,Y.", - "value": "Gigante,C., Thomas,L., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Dunn,J., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-10-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_TN0015" - }, - "strain": { - "value": "OQ427123" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150566-", - "T150567-", - "G170311A", - "T170897-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "C180606T", - "-196603A" - ], - "OPG198": [ - "E92K" - ], - "OPG209": [ - "S30L" - ] - }, - "labels": { - "aa": "OPG198: E92K; OPG209: S30L" - } - } - }, - { - "name": "NY-NYCPHL-000185", - "node_attrs": { - "div": 63, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-30" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000185" - }, - "strain": { - "value": "OQ468823" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150566-", - "T150567A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - }, - { - "name": "NY-NYCPHL-000186", - "node_attrs": { - "div": 63, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-30" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000186" - }, - "strain": { - "value": "OQ468824" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - }, - { - "name": "NY-NYCPHL-000288", - "node_attrs": { - "div": 64, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-03" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000288" - }, - "strain": { - "value": "OQ469072" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150566-", - "T150567-", - "C155209T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - }, - { - "name": "NY-NYCPHL-001078", - "node_attrs": { - "div": 65, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-05" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-001078" - }, - "strain": { - "value": "OQ469260" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T495C", - "G86088A", - "C137400T", - "G150550-", - "-150563A", - "-150564T", - "-150565G", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG153": [ - "E90K" - ] - }, - "labels": { - "aa": "OPG153: E90K" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00424/2022", - "node_attrs": { - "div": 74, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-12-05" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00424/2022" - }, - "strain": { - "value": "OQ503817" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C10929T", - "C25674T", - "C43493T", - "G51358A", - "C78473T", - "C90900T", - "G99544A", - "G102694A", - "G126646A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150563A", - "-150564T", - "-150565G", - "C168226T", - "C168586T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ], - "OPG023": [ - "E658K" - ], - "OPG063": [ - "D66N" - ], - "OPG070": [ - "E257K" - ], - "OPG118": [ - "E367K" - ], - "OPG148": [ - "E221K" - ] - }, - "labels": { - "aa": "OPG023: E658K; OPG063: D66N; OPG070: E257K; OPG118: E367K; OPG148: E221K" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00405/2023", - "node_attrs": { - "div": 70, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-01-10" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00405/2023" - }, - "strain": { - "value": "OQ503828" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T515-", - "T516-", - "T517-", - "G25309A", - "G28271A", - "G112785A", - "T118096C", - "G133968T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150563A", - "-150564T", - "-150565G", - "C165231T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "C180371T", - "T196584-", - "C196585-", - "A196586-" - ], - "OPG040": [ - "S57L" - ], - "OPG044": [ - "D61N" - ], - "OPG136": [ - "M498V" - ], - "OPG190": [ - "S37L" - ] - }, - "labels": { - "aa": "OPG040: S57L; OPG044: D61N; OPG136: M498V; OPG190: S37L" - } - } - }, - { - "name": "NY-NYCPHL-000813", - "node_attrs": { - "div": 63, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-13" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000813" - }, - "strain": { - "value": "OQ565452" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150563A", - "-150564T", - "-150565G", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_164/Belgium/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-07-27" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_164/Belgium/2022" - }, - "strain": { - "value": "OR086973" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G135633A", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150566-", - "T150567-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ] - } - } - }, - { - "name": "hMpxV/USA/CACDPH1MPX1000172/2023", - "node_attrs": { - "div": 69, - "author": { - "author": "Kath,C., Haw,M., Espinosa,A., Hacker,J.", - "value": "Kath,C., Haw,M., Espinosa,A., Hacker,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-01-12" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/USA/CACDPH1MPX1000172/2023" - }, - "strain": { - "value": "OR178739" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T548-", - "A549-", - "A550-", - "G2126A", - "G39327A", - "C64132T", - "C110699T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150563A", - "-150564T", - "-150565G", - "C154736T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "G183791A", - "C195084T" - ], - "OPG002": [ - "S209L" - ], - "OPG057": [ - "A290V" - ], - "OPG083": [ - "M195I" - ], - "OPG181": [ - "P109S" - ] - }, - "labels": { - "aa": "OPG002: S209L; OPG057: A290V; OPG083: M195I; OPG181: P109S" - } - } - }, - { - "name": "MPXV_USA_2022_LA0015", - "node_attrs": { - "div": 65, - "author": { - "author": "Li,C.M.", - "value": "Li,C.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_LA0015" - }, - "strain": { - "value": "OR209318" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "A15347-", - "G15348-", - "C15349-", - "T15350-", - "C15351-", - "A15352-", - "T15353-", - "A15354-", - "T15355-", - "G15356-", - "A15357-", - "T15358-", - "T15359-", - "T15360-", - "C15361-", - "A15362-", - "G15363-", - "T15364-", - "A15365-", - "C15366-", - "T15367-", - "G15368-", - "T15369-", - "A15370-", - "G15371-", - "T15372-", - "G15373-", - "T15374-", - "C15375-", - "A15376-", - "G15377-", - "T15378-", - "A15379-", - "C15380-", - "T15381-", - "A15382-", - "T15383-", - "T15384-", - "A15385-", - "G15386-", - "T15387-", - "T15388-", - "T15389-", - "C15390-", - "G15391-", - "A15392-", - "T15393-", - "C15394-", - "A15395-", - "G15396-", - "A15397-", - "T15398-", - "C15399-", - "A15400-", - "A15401-", - "T15402-", - "G15403-", - "T15404-", - "C15405-", - "T15406-", - "A15407-", - "G15408-", - "A15409-", - "T15410-", - "C15411-", - "T15412-", - "A15413-", - "T15414-", - "A15415-", - "G15416-", - "A15417-", - "A15418-", - "T15419-", - "C15420-", - "A15421-", - "C105161T", - "T133078-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150566-", - "T150567-", - "C168943T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-196603A" - ], - "OPG124": [ - "D270N" - ] - }, - "labels": { - "aa": "OPG124: D270N" - } - } - }, - { - "name": "NODE_0000200", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C160426T", - "-196601A", - "-196602A", - "-196603A" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/ON/RKI446", - "node_attrs": { - "div": 66, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI446" - }, - "strain": { - "value": "OP615326" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C101983T", - "C141757T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150563A", - "-150564T", - "-150565G", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ], - "OPG121": [ - "S65L" - ] - }, - "labels": { - "aa": "OPG121: S65L" - } - } - }, - { - "name": "MPXV22/human/USA-NE-341", - "node_attrs": { - "div": 66, - "author": { - "author": "Tegomoh,B., Cross,S.T., Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., Pratt,C.B., Warden,D.E., Iwen,P.C., Donahue,M., Wiley,M.R.", - "value": "Tegomoh,B., Cross,S.T., Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., Pratt,C.B., Warden,D.E., Iwen,P.C., Donahue,M., Wiley,M.R." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-10-11" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV22/human/USA-NE-341" - }, - "strain": { - "value": "OQ626772" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "G10523A", - "T16609-", - "C16610-", - "A16611-", - "G92433A", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150566-", - "T150567-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG029": [ - "D153X", - "D154X", - "*156X" - ], - "OPG113": [ - "A235T" - ] - }, - "labels": { - "aa": "OPG029: D153X, D154X, *156X; OPG113: A235T" - } - } - } - ] - }, - { - "name": "NODE_0000201", - "node_attrs": { - "div": 67, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T26669C", - "G96073A", - "G115235A", - "C125294T", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150566-", - "T150567-" - ], - "OPG117": [ - "D9N" - ] - }, - "labels": { - "aa": "OPG117: D9N" - } - }, - "children": [ - { - "name": "BOL-UNIMOL-MPX-293419-L", - "node_attrs": { - "div": 67, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-10-27" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "BOL-UNIMOL-MPX-293419-L" - }, - "strain": { - "value": "OP959058" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "BOL-UNIMOL-MPX-293428-L", - "node_attrs": { - "div": 67, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "country": { - "value": "Colombia" - }, - "date": { - "value": "2022-10-29" - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "BOL-UNIMOL-MPX-293428-L" - }, - "strain": { - "value": "OP959060" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Germany/2022/RKI632", - "node_attrs": { - "div": 69, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-11-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI632" - }, - "strain": { - "value": "OQ159027" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G77052A", - "C135868T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ] - } - } - } - ] - }, - { - "name": "NODE_0000202", - "node_attrs": { - "div": 69, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G8638A", - "C21548T", - "C47820T", - "C68218T", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150566-", - "T150567-", - "C188236T", - "C188339T" - ], - "OPG037": [ - "D296N" - ], - "OPG085": [ - "R105Q" - ] - }, - "labels": { - "aa": "OPG037: D296N; OPG085: R105Q" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-041886/2023", - "node_attrs": { - "div": 69, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-04-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-041886/2023" - }, - "strain": { - "value": "OQ979622" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "T133079-" - ] - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-048370/2023", - "node_attrs": { - "div": 71, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-04-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-048370/2023" - }, - "strain": { - "value": "OQ979623" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C70252T", - "C102741T" - ], - "OPG122": [ - "S105L" - ] - }, - "labels": { - "aa": "OPG122: S105L" - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-028492/2023", - "node_attrs": { - "div": 71, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-02-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-028492/2023" - }, - "strain": { - "value": "OQ979624" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G12239A", - "G12488A", - "-196603A" - ], - "OPG023": [ - "S138L", - "S221F" - ] - }, - "labels": { - "aa": "OPG023: S138L, S221F" - } - } - } - ] - }, - { - "name": "NODE_0000203", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G45781A", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-" - ], - "OPG064": [ - "H40Y" - ] - }, - "labels": { - "aa": "OPG064: H40Y" - } - }, - "children": [ - { - "name": "Monkeypox/PT0554/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-30" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0554/2022" - }, - "strain": { - "value": "OP555625" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G29102A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150563A", - "-150564T", - "-150565G", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ], - "OPG045": [ - "S54L" - ] - }, - "labels": { - "aa": "OPG045: S54L" - } - } - }, - { - "name": "MPXV22/human/USA-OK-270", - "node_attrs": { - "div": 69, - "author": { - "author": "Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., O'Dell,J.X., Mannell,M., Wiley,M.R., Cross,S.T.", - "value": "Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., O'Dell,J.X., Mannell,M., Wiley,M.R., Cross,S.T." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-06" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV22/human/USA-OK-270" - }, - "strain": { - "value": "OP650030" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "G4216T", - "C27184T", - "C46430A", - "G111840A", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150566-", - "T150567-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "A182635T", - "C192994A", - "-196601A", - "-196602A", - "-196603A" - ], - "OPG003": [ - "P131H" - ], - "OPG043": [ - "E258K" - ], - "OPG065": [ - "M18I" - ], - "OPG210": [ - "D427V" - ] - }, - "labels": { - "aa": "OPG003: P131H; OPG043: E258K; OPG065: M18I; OPG210: D427V" - } - } - }, - { - "name": "B1221119", - "node_attrs": { - "div": 69, - "author": { - "author": "Bajwa,M.I., Miller,H.", - "value": "Bajwa,M.I., Miller,H." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-11-08" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Delaware Public Health Lab, Sequencing/Bioinformatics" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "B1221119" - }, - "strain": { - "value": "OP935996" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G2146A", - "C106706T", - "G129859A", - "C138639T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150563A", - "-150564T", - "-150565G", - "G153765A", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "C195064T" - ], - "OPG125": [ - "E317K" - ], - "OPG156": [ - "M257I" - ] - }, - "labels": { - "aa": "OPG125: E317K; OPG156: M257I" - } - } - }, - { - "name": "MPXV_USA_2022_GA0023", - "node_attrs": { - "div": 66, - "author": { - "author": "Gigante,C., Pavlick,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Parrott,T., Li,Y.", - "value": "Gigante,C., Pavlick,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Parrott,T., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_GA0023" - }, - "strain": { - "value": "OQ320516" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C33103T", - "C119557T", - "A136513-", - "T136514-", - "C136515-", - "C140057T", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150566-", - "T150567-", - "-196603A" - ], - "OPG049": [ - "E17K" - ], - "OPG136": [ - "D11N" - ], - "OPG153": [ - "D385-" - ], - "OPG159": [ - "S97L" - ] - }, - "labels": { - "aa": "OPG049: E17K; OPG136: D11N; OPG153: D385-; OPG159: S97L" - } - } - } - ] - }, - { - "name": "NODE_0000204", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150563A", - "-150564T", - "-150565G", - "T157527C", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI063", - "node_attrs": { - "div": 66, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI063" - }, - "strain": { - "value": "ON813263" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G55173A", - "T188391C" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI169", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI169" - }, - "strain": { - "value": "OP018588" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV_UK_2022_9000067", - "node_attrs": { - "div": 65, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-06-08" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000067" - }, - "strain": { - "value": "OP205073" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C88757T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG109": [ - "D231N" - ] - }, - "labels": { - "aa": "OPG109: D231N" - } - } - }, - { - "name": "Monkeypox/PT0387/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-07-12" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0387/2022" - }, - "strain": { - "value": "OP555483" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G154098A" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI566", - "node_attrs": { - "div": 65, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI566" - }, - "strain": { - "value": "OP764624" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C7170T" - ] - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00442/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-11-27" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00442/2022" - }, - "strain": { - "value": "OQ503794" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G23127A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A196429-", - "G196430-", - "A196431-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI812", - "node_attrs": { - "div": 66, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI812" - }, - "strain": { - "value": "OQ773431" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.2" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C1143T", - "C21446T", - "G131501A", - "G150550-", - "A150563-", - "T150564-", - "G150565-", - "T178896-", - "T178897-", - "A178898-", - "C178899-", - "A178900-", - "A178901-", - "G178902-", - "A178903-", - "T178904-", - "A178905-", - "C178906-", - "A178907-", - "T178908-", - "T178909-", - "T178910-", - "A178911-", - "A178912-", - "T178913-", - "G178914-", - "T178915-", - "G178916-", - "C178917-", - "T178918-", - "T178919-", - "A178920-", - "C178921-", - "G178922-", - "G178923-", - "A178924-", - "A178925-", - "C178926-", - "A178927-", - "T178928-", - "A178929-", - "T178930-", - "A178931-", - "T178932-", - "T178933-", - "T178934-", - "A178935-", - "G178936-", - "A178937-", - "A178938-", - "A178939-", - "C178940-", - "A178941-", - "T178942-", - "C178943-", - "T178944-", - "A178945-", - "C178946-", - "T178947-", - "A178948-", - "A178949-", - "C178950-", - "G178951-", - "A178952-", - "T178953-", - "T178954-", - "T178955-", - "T178956-", - "T178957-", - "T178958-", - "A178959-", - "T178960-", - "G178961-", - "C178962-", - "T178963-", - "T178964-", - "G178965-", - "T178966-", - "A178967-" - ], - "OPG037": [ - "E330K" - ], - "OPG151": [ - "E860K" - ] - }, - "labels": { - "aa": "OPG037: E330K; OPG151: E860K" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000232", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C25644T", - "-150559G", - "-150566A", - "-150567T" - ] - }, - "labels": { - "clade": "B.1.7" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_NY0037", - "node_attrs": { - "div": 64, - "author": { - "author": "Gigante,C., Ruiz,V., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Wang,J., Li,Y.", - "value": "Gigante,C., Ruiz,V., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Wang,J., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_NY0037" - }, - "strain": { - "value": "OQ320467" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G98456A", - "C103258T", - "G150559-", - "A150566-", - "T150567-" - ], - "OPG118": [ - "G4E" - ], - "OPG123": [ - "D605N" - ] - }, - "labels": { - "aa": "OPG118: G4E; OPG123: D605N" - } - } - }, - { - "name": "MPXV_UK_2022_9000064", - "node_attrs": { - "div": 62, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-06-06" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000064" - }, - "strain": { - "value": "OP205070" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150559-", - "A150566-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI274", - "node_attrs": { - "div": 66, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI274" - }, - "strain": { - "value": "OP263628" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C66249T", - "C88644A", - "C104134T", - "C112638T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G" - ], - "OPG109": [ - "K268N" - ], - "OPG123": [ - "A313T" - ] - }, - "labels": { - "aa": "OPG109: K268N; OPG123: A313T" - } - } - }, - { - "name": "MPX_Yob5K4_9000202", - "node_attrs": { - "div": 65, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_Yob5K4_9000202" - }, - "strain": { - "value": "OP415183" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G56745A", - "C88394T", - "G150559-", - "A150566-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "G187367A" - ], - "OPG109": [ - "E352K" - ] - }, - "labels": { - "aa": "OPG109: E352K" - } - } - }, - { - "name": "9000452", - "node_attrs": { - "div": 63, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000452" - }, - "strain": { - "value": "OP536814" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A57256G", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "NY-NYCPHL-000077", - "node_attrs": { - "div": 62, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-13" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000077" - }, - "strain": { - "value": "OQ469126" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A136513-", - "T136514-", - "C136515-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150565G", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI720", - "node_attrs": { - "div": 62, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI720" - }, - "strain": { - "value": "OQ547747" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T" - ] - } - } - }, - { - "name": "MPXV_UK_2022_9000078", - "node_attrs": { - "div": 62, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-06-14" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000078" - }, - "strain": { - "value": "OP205081" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150559-", - "A150566-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "Monkeypox/PT0031/2022", - "node_attrs": { - "div": 62, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-05-26" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0031/2022" - }, - "strain": { - "value": "ON843170" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G" - ] - } - } - }, - { - "name": "9000422", - "node_attrs": { - "div": 62, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000422" - }, - "strain": { - "value": "OP536796" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A196604-" - ] - } - } - }, - { - "name": "NODE_0000131", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G50034A", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196603A" - ], - "OPG069": [ - "E17K" - ] - }, - "labels": { - "aa": "OPG069: E17K" - } - }, - "children": [ - { - "name": "9000396", - "node_attrs": { - "div": 64, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000396" - }, - "strain": { - "value": "OP536774" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G74200A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T" - ], - "OPG094": [ - "D141N" - ] - }, - "labels": { - "aa": "OPG094: D141N" - } - } - }, - { - "name": "NY-NYCPHL-000067", - "node_attrs": { - "div": 64, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-14" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000067" - }, - "strain": { - "value": "OQ469026" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "G169350A", - "G188710A" - ] - } - } - } - ] - }, - { - "name": "NODE_0000114", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C14077T", - "G150559-", - "A150566-", - "T150567-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - }, - "children": [ - { - "name": "MPXV_UK_2022_9000093", - "node_attrs": { - "div": 65, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-05-30" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000093" - }, - "strain": { - "value": "OP205084" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C4529T", - "G155585A", - "G192681A" - ], - "OPG003": [ - "D27N" - ] - }, - "labels": { - "aa": "OPG003: D27N" - } - } - }, - { - "name": "MPX_cmjxZM_9000205", - "node_attrs": { - "div": 63, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_cmjxZM_9000205" - }, - "strain": { - "value": "OP415186" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000115", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G105860A" - ] - } - }, - "children": [ - { - "name": "MPX_2v76E1_9000221", - "node_attrs": { - "div": 66, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_2v76E1_9000221" - }, - "strain": { - "value": "OP415197" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G41557A", - "G91376A" - ], - "OPG061": [ - "P110S" - ], - "OPG112": [ - "D44N" - ] - }, - "labels": { - "aa": "OPG061: P110S; OPG112: D44N" - } - } - }, - { - "name": "MPXV/UZ_REGA_245/Belgium/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-08-16" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_245/Belgium/2022" - }, - "strain": { - "value": "OR095063" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T149487-", - "A149488-", - "C149489-", - "G149490-", - "T149491-", - "T149492-", - "G149493-", - "A149494-", - "A149495-", - "C149496-", - "A149497-", - "A149498-", - "G149499-", - "T149500-", - "C149501-", - "C149502-", - "A149503-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T" - ], - "OPG175": [ - "Y16-", - "V17-", - "E18-", - "Q19-", - "V20-", - "H21X", - "*126X" - ] - }, - "labels": { - "aa": "OPG175: Y16-, V17-, E18-, Q19-, V20-, H21X, *126X" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000116", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G63147A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI083", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI083" - }, - "strain": { - "value": "ON853665" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G73398A" - ], - "OPG093": [ - "E141K" - ] - }, - "labels": { - "aa": "OPG093: E141K" - } - } - }, - { - "name": "MPX_WOcPOH_9000297", - "node_attrs": { - "div": 68, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_WOcPOH_9000297" - }, - "strain": { - "value": "OP415252" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C15004T", - "T80587C", - "C101845T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "C155483T", - "G177780A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG121": [ - "S19F" - ], - "OPG205": [ - "E709K" - ] - }, - "labels": { - "aa": "OPG121: S19F; OPG205: E709K" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI396", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI396" - }, - "strain": { - "value": "OP523999" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A136513-", - "T136514-", - "C136515-", - "-196603A" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "NODE_0000117", - "node_attrs": { - "div": 67, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G10224A", - "G129761A", - "T143625A", - "C177847T", - "-196603A" - ], - "OPG021": [ - "R213Q" - ], - "OPG151": [ - "D280N" - ], - "OPG165": [ - "I37N" - ], - "OPG205": [ - "S731L" - ] - }, - "labels": { - "aa": "OPG021: R213Q; OPG151: D280N; OPG165: I37N; OPG205: S731L" - } - }, - "children": [ - { - "name": "NICD-SVPL223", - "node_attrs": { - "div": 67, - "author": { - "author": "Chan,W.Y., Mtshali,S., Grobbelaar,A., Moolla,N., Mohale,T., Lowe,M., Du Plessis,M., Ismail,A., Weyer,J.", - "value": "Chan,W.Y., Mtshali,S., Grobbelaar,A., Moolla,N., Mohale,T., Lowe,M., Du Plessis,M., Ismail,A., Weyer,J." - }, - "country": { - "value": "South Africa" - }, - "date": { - "value": "2022-06-20" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "National Institute for Communicable Disease, Sequencing Core Facility" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NICD-SVPL223" - }, - "strain": { - "value": "ON918611" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T" - ] - } - } - }, - { - "name": "NICD-SVPL232", - "node_attrs": { - "div": 67, - "author": { - "author": "Chan,W.Y., Mtshali,P.S., Grobbelaar,A., Moolla,N., Mohale,T., Lowe,M., Du Plessis,M., Ismail,A., Weyer,J.", - "value": "Chan,W.Y., Mtshali,P.S., Grobbelaar,A., Moolla,N., Mohale,T., Lowe,M., Du Plessis,M., Ismail,A., Weyer,J." - }, - "country": { - "value": "South Africa" - }, - "date": { - "value": "2022-06-24" - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "National Institute for Communicable Disease, Sequencing core facility" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NICD-SVPL232" - }, - "strain": { - "value": "ON927248" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A196603C" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000118", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C148771T", - "G150559-", - "A150566-", - "T150567-" - ], - "OPG174": [ - "D209N" - ] - }, - "labels": { - "aa": "OPG174: D209N" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/ON/RKI701", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI701" - }, - "strain": { - "value": "OQ417834" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C11747-", - "C126926T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ], - "OPG023": [ - "G385X", - "*661X" - ], - "OPG148": [ - "A314V" - ] - }, - "labels": { - "aa": "OPG023: G385X, *661X; OPG148: A314V" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI804", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI804" - }, - "strain": { - "value": "OQ773423" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C68429T", - "G150550-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG085": [ - "E35K" - ] - }, - "labels": { - "aa": "OPG085: E35K" - } - } - }, - { - "name": "NODE_0000119", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G114316A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A" - ], - "OPG133": [ - "H461Y" - ] - }, - "labels": { - "aa": "OPG133: H461Y" - } - }, - "children": [ - { - "name": "MPXV/UZ_REGA_197/Belgium/2022", - "node_attrs": { - "div": 68, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-08-03" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_197/Belgium/2022" - }, - "strain": { - "value": "OR087006" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C12637T", - "G53377A", - "T133078-", - "C178569T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "C182707T" - ], - "OPG210": [ - "S451F" - ] - }, - "labels": { - "aa": "OPG210: S451F" - } - } - }, - { - "name": "NODE_0000120", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G152437A" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI631", - "node_attrs": { - "div": 66, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-10-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI631" - }, - "strain": { - "value": "OQ159026" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150547A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "G187677A" - ] - } - } - }, - { - "name": "INMI-19442022", - "node_attrs": { - "div": 65, - "author": { - "author": "Rueca,M., Tucci,F.G., Mazzotta,V., Gramigna,G., Gruber,C.E.M., Fabeni,L., Giombini,E., Matusali,G., Pinnetti,C., Mariano,A., Butera,O., Specchiarello,E., Mondi,A., Lanini,S., Carletti,F., Girardi,E., Vaia,F., Nicastri,E., Antinori,A., Maggi,F.", - "value": "Rueca,M., Tucci,F.G., Mazzotta,V., Gramigna,G., Gruber,C.E.M., Fabeni,L., Giombini,E., Matusali,G., Pinnetti,C., Mariano,A., Butera,O., Specchiarello,E., Mondi,A., Lanini,S., Carletti,F., Girardi,E., Vaia,F., Nicastri,E., Antinori,A., Maggi,F." - }, - "country": { - "value": "Italy" - }, - "date": { - "value": "2022-09-14" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute for Infectious Diseases \"L. Spallanzani\" - IRCCS, Laboratory of Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "INMI-19442022" - }, - "strain": { - "value": "OQ627928" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A586-", - "A587-", - "A588-", - "-594T", - "A196599-", - "C196600-", - "-196602A" - ] - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000134", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G42504A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G" - ] - } - }, - "children": [ - { - "name": "PatientMPXV", - "node_attrs": { - "div": 64, - "author": { - "author": "Seang,S., Burrel,S., Todesco,E., Leducq,V., Monsel,G., Le Pluart,D., Cordevant,C., Pourcher,V., Palich,R., Charpentier,C.", - "value": "Seang,S., Burrel,S., Todesco,E., Leducq,V., Monsel,G., Le Pluart,D., Cordevant,C., Pourcher,V., Palich,R., Charpentier,C." - }, - "country": { - "value": "France" - }, - "date": { - "value": "2022-06-10" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "APHP Pitie Salpetriere SU, Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "PatientMPXV" - }, - "strain": { - "value": "OP204840" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G163250A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A196604-", - "A196605-", - "A196606-" - ] - } - } - }, - { - "name": "MPX/PT0050/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-01" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX/PT0050/2022" - }, - "strain": { - "value": "OP245307" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A470-", - "G471-", - "C134850T", - "C159741T", - "G196413-", - "T196414-" - ] - } - } - }, - { - "name": "Monkeypox/PT0493/2022", - "node_attrs": { - "div": 70, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-11" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0493/2022" - }, - "strain": { - "value": "OP555568" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C5292T", - "G11924A", - "G74267A", - "C115870T", - "G125379A", - "A161784T", - "G176342A", - "G191918A" - ], - "NBT03_gp175": [ - "D289N" - ], - "OPG015": [ - "D289N" - ], - "OPG023": [ - "S326L" - ], - "OPG094": [ - "R163Q" - ], - "OPG145": [ - "R478K" - ] - }, - "labels": { - "aa": "NBT03_gp175: D289N; OPG015: D289N; OPG023: S326L; OPG094: R163Q; OPG145: R478K" - } - } - }, - { - "name": "NODE_0000135", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G186537A" - ], - "OPG210": [ - "E1728K" - ] - }, - "labels": { - "aa": "OPG210: E1728K" - } - }, - "children": [ - { - "name": "Monkeypox/PT0216/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-06-24" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0216/2022" - }, - "strain": { - "value": "OP324526" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0225/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-06-22" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0225/2022" - }, - "strain": { - "value": "OP324535" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000121", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G120241A", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G" - ], - "OPG137": [ - "D214N" - ] - }, - "labels": { - "aa": "OPG137: D214N" - } - }, - "children": [ - { - "name": "Monkeypox/MX-UANL001/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Galan-Huerta,K.A., Paz-Infanzon,M., Ruiz-Higareda,A.F., Nuzzolo-Shihadeh,L., Camacho-Ortiz,A., Bocanegra-Ibarias,P., Rivas-Estilla,A.M., Zacarias-Villarreal,D., Yamallel-Ortega,L.A., Guerrero-Putz,M.D., Ocampo-Candiani,J.", - "value": "Galan-Huerta,K.A., Paz-Infanzon,M., Ruiz-Higareda,A.F., Nuzzolo-Shihadeh,L., Camacho-Ortiz,A., Bocanegra-Ibarias,P., Rivas-Estilla,A.M., Zacarias-Villarreal,D., Yamallel-Ortega,L.A., Guerrero-Putz,M.D., Ocampo-Candiani,J." - }, - "country": { - "value": "Mexico" - }, - "date": { - "value": "2022-06-28" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Universidad Autonoma de Nuevo Leon - Facultad de Medicina, Centro de Investigacion e Innovacion en Virologia Medica" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/MX-UANL001/2022" - }, - "strain": { - "value": "ON911481" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G57088A", - "C127530T", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "T168120C", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196601A", - "-196602A", - "-196603A" - ], - "OPG074": [ - "S13L" - ], - "OPG149": [ - "S112L" - ], - "OPG193": [ - "F263L" - ] - }, - "labels": { - "aa": "OPG074: S13L; OPG149: S112L; OPG193: F263L" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI165", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI165" - }, - "strain": { - "value": "ON959153" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "G170557A" - ], - "OPG198": [ - "E174K" - ] - }, - "labels": { - "aa": "OPG198: E174K" - } - } - }, - { - "name": "MPX/PT0058/2022", - "node_attrs": { - "div": 63, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-07-28" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX/PT0058/2022" - }, - "strain": { - "value": "OP245314" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI361", - "node_attrs": { - "div": 65, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI361" - }, - "strain": { - "value": "OP484682" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "C168226T", - "C175467T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI544", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI544" - }, - "strain": { - "value": "OP715824" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T" - ] - } - } - }, - { - "name": "MPXV_USA_2022_DE0001", - "node_attrs": { - "div": 63, - "author": { - "author": "Gigante,C., Moreno-Gorrin,C., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Miller,H., Li,Y.", - "value": "Gigante,C., Moreno-Gorrin,C., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Miller,H., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_DE0001" - }, - "strain": { - "value": "OP881944" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "A136513-", - "T136514-", - "C136515-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "NY-NYCPHL-000972", - "node_attrs": { - "div": 63, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-10" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000972" - }, - "strain": { - "value": "OQ468544" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "T133079-", - "T133080-", - "A136513-", - "T136514-", - "C136515-", - "G150550-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - } - ] - }, - { - "name": "NODE_0000136", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C57173T", - "G150559-", - "A150566-", - "T150567-" - ] - } - }, - "children": [ - { - "name": "PrEV_case_2", - "node_attrs": { - "div": 70, - "author": { - "author": "Berens-Riha,N., De Block,T., Rutgers,J., Van Gestel,L., Hens,M., Kenyon,C., Soentjens,P., Van Griensven,J., Brosius,I., Arien,K., Van Esbroeck,M., Rezende,A.M., Vercauteren,K.", - "value": "Berens-Riha,N., De Block,T., Rutgers,J., Van Gestel,L., Hens,M., Kenyon,C., Soentjens,P., Van Griensven,J., Brosius,I., Arien,K., Van Esbroeck,M., Rezende,A.M., Vercauteren,K." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-10-02" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "PrEV_case_2" - }, - "strain": { - "value": "OP727822" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T348-", - "G349-", - "G350-", - "A351-", - "T352-", - "T353-", - "C11401T", - "C33964T", - "C36267T", - "G110285A", - "T133078-", - "C144366T", - "A174924T", - "G180608A", - "A188349-", - "G195316A" - ], - "OPG052": [ - "R11Q" - ], - "OPG055": [ - "D273N" - ], - "OPG209": [ - "E31K" - ] - }, - "labels": { - "aa": "OPG052: R11Q; OPG055: D273N; OPG209: E31K" - } - } - }, - { - "name": "NODE_0000137", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C142797T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG164": [ - "S7L" - ] - }, - "labels": { - "aa": "OPG164: S7L" - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-4112/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Griffiths,E., Jolly,G., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Griffiths,E., Jolly,G., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "country": { - "value": "Canada" - }, - "date": { - "value": "2022-06-30" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-4112/2022" - }, - "strain": { - "value": "OP279036" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0380/2022", - "node_attrs": { - "div": 67, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-07-13" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0380/2022" - }, - "strain": { - "value": "OP555476" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G2185A", - "C21476T", - "G142271A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "C195025T" - ], - "OPG037": [ - "E320K" - ], - "OPG163": [ - "D24N" - ] - }, - "labels": { - "aa": "OPG037: E320K; OPG163: D24N" - } - } - }, - { - "name": "NY-NYCPHL-000364", - "node_attrs": { - "div": 69, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-15" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000364" - }, - "strain": { - "value": "OQ468965" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T25644C", - "C85322T", - "G109704A", - "G143831A", - "C153441T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T" - ], - "OPG129": [ - "S434F" - ], - "OPG165": [ - "D106N" - ] - }, - "labels": { - "aa": "OPG129: S434F; OPG165: D106N" - } - } - }, - { - "name": "NY-NYCPHL-000907", - "node_attrs": { - "div": 64, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-07" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000907" - }, - "strain": { - "value": "OQ565501" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T" - ] - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00486/2023", - "node_attrs": { - "div": 72, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-02-18" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00486/2023" - }, - "strain": { - "value": "OQ918697" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C55036T", - "G73789A", - "C96914T", - "C136435T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G158254A", - "C166803T", - "C170381T", - "G178559A", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-" - ], - "NBT03_gp052": [ - "E36K" - ], - "OPG094": [ - "G4R" - ], - "OPG117": [ - "S289L" - ], - "OPG192": [ - "P25S" - ], - "OPG198": [ - "S115L" - ] - }, - "labels": { - "aa": "NBT03_gp052: E36K; OPG094: G4R; OPG117: S289L; OPG192: P25S; OPG198: S115L" - } - } - }, - { - "name": "MPXV_USA_2022_NC0003", - "node_attrs": { - "div": 65, - "author": { - "author": "Li,C.M.", - "value": "Li,C.M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-12-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_NC0003" - }, - "strain": { - "value": "OR209323" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G62268A", - "A136513-", - "T136514-", - "C136515-", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "A196604-" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "NODE_0000138", - "node_attrs": { - "div": 69, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G105325A", - "C108658T", - "T133078-", - "T133079-", - "C149889T", - "G165395A", - "G184244A", - "-196603A" - ], - "OPG124": [ - "S215F" - ], - "OPG190": [ - "E92K" - ] - }, - "labels": { - "aa": "OPG124: S215F; OPG190: E92K" - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00361/2022", - "node_attrs": { - "div": 70, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-10-31" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00361/2022" - }, - "strain": { - "value": "OP920699" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G111379A", - "-133078T", - "-133079T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ], - "OPG130": [ - "S175L" - ] - }, - "labels": { - "aa": "OPG130: S175L" - } - } - }, - { - "name": "MPXV_USA_2022_DC0015", - "node_attrs": { - "div": 69, - "author": { - "author": "Gigante,C., Hauser,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Knipe,K., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Mangla,A., Li,Y.", - "value": "Gigante,C., Hauser,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Knipe,K., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Mangla,A., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_DC0015" - }, - "strain": { - "value": "OQ320512" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.7" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000205", - "node_attrs": { - "div": 62, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "G190660A" - ], - "NBT03_gp174": [ - "R84K" - ] - }, - "labels": { - "aa": "NBT03_gp174: R84K", - "clade": "B.1.3" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI013", - "node_attrs": { - "div": 63, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI013" - }, - "strain": { - "value": "ON755231" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-596T", - "G80450A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ] - } - } - }, - { - "name": "MPxV/Prague_001/2022/flye_medaka", - "node_attrs": { - "div": 62, - "author": { - "author": "Chmel,M., Pajer,P., Nagy,A., Zlamal,M., Jirincova,H., Dresler,J., Bartos,O.", - "value": "Chmel,M., Pajer,P., Nagy,A., Zlamal,M., Jirincova,H., Dresler,J., Bartos,O." - }, - "country": { - "value": "Czech Republic" - }, - "date": { - "value": "2022-04-28" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Military Heatlh Institute, Military Heatlh Institute in Prague" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPxV/Prague_001/2022/flye_medaka" - }, - "strain": { - "value": "ON983168" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T80841-" - ], - "OPG104": [ - "N60X", - "*134X" - ] - }, - "labels": { - "aa": "OPG104: N60X, *134X" - } - } - }, - { - "name": "9000372", - "node_attrs": { - "div": 68, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000372" - }, - "strain": { - "value": "OP536752" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C40543T", - "G132994A", - "C142586T", - "C150125T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G167802A", - "G167826A", - "A196604-" - ], - "OPG059": [ - "E31K" - ], - "OPG176": [ - "S106F" - ], - "OPG193": [ - "E157K", - "D165N" - ] - }, - "labels": { - "aa": "OPG059: E31K; OPG176: S106F; OPG193: E157K, D165N" - } - } - }, - { - "name": "9000432", - "node_attrs": { - "div": 64, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000432" - }, - "strain": { - "value": "OP536804" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C6423A", - "C135775T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T190786-", - "A196604-" - ], - "NBT03_gp174": [ - "I126X", - "*177X" - ] - }, - "labels": { - "aa": "NBT03_gp174: I126X, *177X" - } - } - }, - { - "name": "PrEV_case_1", - "node_attrs": { - "div": 62, - "author": { - "author": "Berens-Riha,N., De Block,T., Rutgers,J., Van Gestel,L., Hens,M., Kenyon,C., Soentjens,P., Van Griensven,J., Brosius,I., Arien,K., Van Esbroeck,M., Rezende,A.M., Vercauteren,K.", - "value": "Berens-Riha,N., De Block,T., Rutgers,J., Van Gestel,L., Hens,M., Kenyon,C., Soentjens,P., Van Griensven,J., Brosius,I., Arien,K., Van Esbroeck,M., Rezende,A.M., Vercauteren,K." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-08-27" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "PrEV_case_1" - }, - "strain": { - "value": "OP727821" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "G179020-", - "T179021-", - "C179022-", - "G179023-", - "A179024-", - "G179025-", - "T179026-", - "A179027-", - "T179028-", - "G179029-", - "A179030-", - "A179031-", - "T179032-", - "A179033-", - "C179034-", - "G179035-", - "G179036-", - "A179037-", - "G179038-", - "T179039-", - "A179040-", - "C179041-", - "A179042-", - "A179043-", - "A179044-", - "C179045-", - "A179046-", - "T179047-", - "A179048-", - "A179049-", - "A179050-", - "C179051-" - ] - } - } - }, - { - "name": "NY-NYCPHL-001049", - "node_attrs": { - "div": 64, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-27" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-001049" - }, - "strain": { - "value": "OQ469238" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C2315T", - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C170204T", - "G194895A" - ], - "OPG002": [ - "G146E" - ], - "OPG198": [ - "S56F" - ] - }, - "labels": { - "aa": "OPG002: G146E; OPG198: S56F" - } - } - }, - { - "name": "NODE_0000206", - "node_attrs": { - "div": 63, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C64426T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ] - } - }, - "children": [ - { - "name": "MPXV/human/Taiwan/110-525030/2023", - "node_attrs": { - "div": 70, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "country": { - "value": "Taiwan" - }, - "date": { - "value": "2023-03-XX" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/human/Taiwan/110-525030/2023" - }, - "strain": { - "value": "OQ721953" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T597-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C166940T", - "T177665A", - "A177666T", - "A177667T", - "G178104T", - "G178290T", - "T178629A", - "G196412A" - ], - "OPG205": [ - "N670K", - "N671F" - ] - }, - "labels": { - "aa": "OPG205: N670K, N671F" - } - } - }, - { - "name": "NODE_0000207", - "node_attrs": { - "div": 64, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-596T", - "G55133A" - ], - "OPG074": [ - "R665C" - ] - }, - "labels": { - "aa": "OPG074: R665C" - } - }, - "children": [ - { - "name": "MPXV_FR_HCL0001_2022", - "node_attrs": { - "div": 65, - "country": { - "value": "France" - }, - "date": { - "value": "2022-05-22" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Virology, GENomique EPIdemiologique das maladies Infectieuses, France" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_FR_HCL0001_2022" - }, - "strain": { - "value": "ON622722" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C109627A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-" - ], - "OPG129": [ - "A460S" - ] - }, - "labels": { - "aa": "OPG129: A460S" - } - } - }, - { - "name": "MPX-37/Finland/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Kant,R., Smura,T., Vauhkonen,H., Vapalahti,O.", - "value": "Kant,R., Smura,T., Vauhkonen,H., Vapalahti,O." - }, - "country": { - "value": "Finland" - }, - "date": { - "value": "2022-05-24" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Helsinki, Department of Virology, Faculty of Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX-37/Finland/2022" - }, - "strain": { - "value": "ON782021" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - }, - { - "name": "MPXV/Spain/HUNSC_ITER_0001a/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Alcoba-Florez,J., Munoz-Barrera,A., Ciuffreda,L., Rodriguez-Perez,H., Rubio-Rodriguez,L.A., Gil-Campesino,H., Garcia-Martinez de Artola,D., Inigo-Campos,A., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C.", - "value": "Alcoba-Florez,J., Munoz-Barrera,A., Ciuffreda,L., Rodriguez-Perez,H., Rubio-Rodriguez,L.A., Gil-Campesino,H., Garcia-Martinez de Artola,D., Inigo-Campos,A., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C." - }, - "country": { - "value": "Spain" - }, - "date": { - "value": "2022-05-31" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Spain/HUNSC_ITER_0001a/2022" - }, - "strain": { - "value": "ON782054" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G50337A", - "A122238T", - "-133164C", - "-133165A", - "-133166A", - "-133167T", - "-133168C", - "-133169T", - "-133170T", - "-133171T", - "-133172C", - "-133173T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A169759G", - "A193392G", - "T193688C", - "T194099C", - "T194619C", - "T195948C", - "-196603A" - ], - "OPG001": [ - "L105S" - ], - "OPG002": [ - "F54S" - ], - "OPG003": [ - "N264D" - ], - "OPG069": [ - "G118R" - ], - "OPG143": [ - "S360T" - ] - }, - "labels": { - "aa": "OPG001: L105S; OPG002: F54S; OPG003: N264D; OPG069: G118R; OPG143: S360T" - } - } - }, - { - "name": "MPXV/Spain/HUNSC_ITER_0001b/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Alcoba-Florez,J., Munoz-Barrera,A., Ciuffreda,L., Rodriguez-Perez,H., Rubio-Rodriguez,L.A., Gil-Campesino,H., Garcia-Martinez de Artola,D., Inigo-Campos,A., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C.", - "value": "Alcoba-Florez,J., Munoz-Barrera,A., Ciuffreda,L., Rodriguez-Perez,H., Rubio-Rodriguez,L.A., Gil-Campesino,H., Garcia-Martinez de Artola,D., Inigo-Campos,A., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C." - }, - "country": { - "value": "Spain" - }, - "date": { - "value": "2022-05-31" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Spain/HUNSC_ITER_0001b/2022" - }, - "strain": { - "value": "ON782055" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A48265T", - "C48296G", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG068": [ - "D22V" - ] - }, - "labels": { - "aa": "OPG068: D22V" - } - } - }, - { - "name": "hMpxV/Switzerland/ZH-UZH-IMV-3ba6449f/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Kufner,V., Ziltener,G., Zaheri,M., Schmutz,S., Audige,A., Bernasconi,O., Steiner,K., Huder,J., Shah,C., Capaul,R., Bloemberg,G., Boeni,J., Huber,M., Trkola,A.", - "value": "Kufner,V., Ziltener,G., Zaheri,M., Schmutz,S., Audige,A., Bernasconi,O., Steiner,K., Huder,J., Shah,C., Capaul,R., Bloemberg,G., Boeni,J., Huber,M., Trkola,A." - }, - "country": { - "value": "Switzerland" - }, - "date": { - "value": "2022-06-01" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Zurich, Institute of Medical Virology" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "hMpxV/Switzerland/ZH-UZH-IMV-3ba6449f/2022" - }, - "strain": { - "value": "ON792320" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G159376A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG185": [ - "D154N" - ] - }, - "labels": { - "aa": "OPG185: D154N" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI079", - "node_attrs": { - "div": 65, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI079" - }, - "strain": { - "value": "ON853661" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C15947T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG027": [ - "R144K" - ] - }, - "labels": { - "aa": "OPG027: R144K" - } - } - }, - { - "name": "MPXV/ITM_pt_31/Belgium/27-May-2022", - "node_attrs": { - "div": 65, - "author": { - "author": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., Van den Bossche,D., Florence,E., Rezende,A.M., Vercauteren,K., Van Esbroeck,M.", - "value": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., Van den Bossche,D., Florence,E., Rezende,A.M., Vercauteren,K., Van Esbroeck,M." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-05-27" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/ITM_pt_31/Belgium/27-May-2022" - }, - "strain": { - "value": "ON950045" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "G140101-", - "T140102-", - "T140103-", - "A140104-", - "A140105-", - "T140106-", - "A140107-", - "A140108-", - "C140109-", - "A140110-", - "A140111-", - "T140112-", - "T140113-", - "A140114-", - "T140115-", - "A140116-", - "A140117-", - "C140118-", - "A140119-", - "A140120-", - "T140121-", - "T140122-", - "A140123-", - "T140124-", - "A140125-", - "A140126-", - "C140127-", - "A140128-", - "A140129-", - "T140130-", - "T140131-", - "A140132-", - "T140133-", - "A140134-", - "A140135-", - "C140136-", - "A140137-", - "A140138-", - "T140139-", - "T140140-", - "A140141-", - "T140142-", - "A140143-", - "A140144-", - "T140145-", - "T140146-", - "G140147-", - "T140148-", - "T140149-", - "A140150-", - "T140151-", - "A140152-", - "A140153-", - "T140154-", - "A140155-", - "A140156-", - "T140157-", - "T140158-", - "A140159-", - "T140160-", - "A140161-", - "A140162-", - "T140163-", - "T140164-", - "T168120C", - "T179026-", - "A179027-", - "T179028-", - "G179029-", - "A179030-", - "A179031-", - "T179032-", - "A179033-", - "C179034-", - "G179035-", - "G179036-", - "A179037-", - "G179038-", - "T179039-", - "A179040-", - "C179041-", - "A179042-", - "A179043-", - "A179044-", - "C179045-", - "A179046-", - "T179047-", - "A179048-", - "A179049-", - "A179050-", - "C179051-", - "T179052-", - "G179053-", - "A179054-", - "A179055-", - "G179056-", - "T179057-", - "-196603A" - ], - "OPG159": [ - "V112-", - "N113-", - "N114-", - "N115-", - "Y116-", - "N117-", - "N118-", - "Y119-", - "N120-", - "N121-", - "Y122-", - "N123-", - "N124-", - "Y125-", - "N126-", - "C127-", - "Y128-", - "N129-", - "N130-", - "Y131-", - "N132-", - "C133X", - "*146X" - ], - "OPG193": [ - "F263L" - ] - }, - "labels": { - "aa": "OPG159: V112-, N113-, N114-, N115-, Y116-, N117-, N118-, Y119-, N120-, N121-, Y122-, N123-, N124-, Y125-, N126-, C127-, Y128-, N129-, N130-, Y131-, N132-, C133X, *146X; OPG193: F263L" - } - } - }, - { - "name": "MPXV_UK_2022_9000061", - "node_attrs": { - "div": 64, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-05-27" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000061" - }, - "strain": { - "value": "OP205067" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196603A" - ] - } - } - }, - { - "name": "MPXV_UK_2022_9000188", - "node_attrs": { - "div": 65, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-06-29" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000188" - }, - "strain": { - "value": "OP205133" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C142545T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196603A" - ], - "OPG163": [ - "S115F" - ] - }, - "labels": { - "aa": "OPG163: S115F" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI311", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI311" - }, - "strain": { - "value": "OP355570" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A188349-" - ] - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-082770/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-082770/2022" - }, - "strain": { - "value": "OP392540" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G143066A", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG164": [ - "D97N" - ] - }, - "labels": { - "aa": "OPG164: D97N" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI392", - "node_attrs": { - "div": 67, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI392" - }, - "strain": { - "value": "OP523994" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G36659A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G174642A", - "C190444T" - ], - "NBT03_gp174": [ - "S12L" - ], - "OPG055": [ - "A142V" - ], - "OPG204": [ - "M37I" - ] - }, - "labels": { - "aa": "NBT03_gp174: S12L; OPG055: A142V; OPG204: M37I" - } - } - }, - { - "name": "Monkeypox/PT0514/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-16" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0514/2022" - }, - "strain": { - "value": "OP555585" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A136513-", - "T136514-", - "C136515-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "Monkeypox/PT0518/2022", - "node_attrs": { - "div": 64, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-08-17" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0518/2022" - }, - "strain": { - "value": "OP555589" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "A136513-", - "T136514-", - "C136515-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A196604-" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "Monkeypox/PT0562/2022", - "node_attrs": { - "div": 65, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-09-01" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0562/2022" - }, - "strain": { - "value": "OP555633" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A136513-", - "T136514-", - "C136515-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C168066T" - ], - "OPG153": [ - "D385-" - ], - "OPG193": [ - "Q245*" - ] - }, - "labels": { - "aa": "OPG153: D385-; OPG193: Q245*" - } - } - }, - { - "name": "NJ-MPXV-017-rep2", - "node_attrs": { - "div": 64, - "author": { - "author": "Palmateer,N.C.", - "value": "Palmateer,N.C." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-06-29" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "New Jersey Department of Health, Public Health and Environmental Laboratories" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NJ-MPXV-017-rep2" - }, - "strain": { - "value": "OP879736" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - }, - { - "name": "MPXV_USA_2022_IA0002", - "node_attrs": { - "div": 64, - "author": { - "author": "Gigante,C., Hottel,W., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nelson,M., Li,Y.", - "value": "Gigante,C., Hottel,W., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nelson,M., Li,Y." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_USA_2022_IA0002" - }, - "strain": { - "value": "OQ054221" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "A196604-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI669", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI669" - }, - "strain": { - "value": "OQ274888" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A152668-", - "T152680-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI670", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI670" - }, - "strain": { - "value": "OQ274889" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A152668-", - "T152680-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI834", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI834" - }, - "strain": { - "value": "OQ773453" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI851", - "node_attrs": { - "div": 64, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI851" - }, - "strain": { - "value": "OQ773470" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_80", - "node_attrs": { - "div": 65, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-08-09" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_80" - }, - "strain": { - "value": "OR035686" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C22950T", - "T133078-", - "T133079-", - "C133161T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_109", - "node_attrs": { - "div": 64, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-10-28" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_109" - }, - "strain": { - "value": "OR035715" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "T195509-", - "A195510-", - "A195511-" - ] - } - } - }, - { - "name": "RNA", - "node_attrs": { - "div": 66, - "country": { - "value": "Slovakia" - }, - "date": { - "value": "2022-07-04" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "RNA" - }, - "strain": { - "value": "OX248696" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G37250A", - "C138080T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A196604-" - ], - "OPG155": [ - "E138K" - ] - }, - "labels": { - "aa": "OPG155: E138K" - } - } - }, - { - "name": "MPXV22/human/USA-NE-181", - "node_attrs": { - "div": 64, - "author": { - "author": "Tegomoh,B., Cross,S.T., Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., Pratt,C.B., Warden,D.E., Iwen,P.C., Donahue,M., Wiley,M.R.", - "value": "Tegomoh,B., Cross,S.T., Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., Pratt,C.B., Warden,D.E., Iwen,P.C., Donahue,M., Wiley,M.R." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-08-17" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV22/human/USA-NE-181" - }, - "strain": { - "value": "OP431828" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196601A", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "MPX_z0MIuQ_9000282", - "node_attrs": { - "div": 64, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPX_z0MIuQ_9000282" - }, - "strain": { - "value": "OP415244" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A196604-" - ] - } - } - }, - { - "name": "MPXV_SI2022_S4", - "node_attrs": { - "div": 64, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "country": { - "value": "Slovenia" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_SI2022_S4" - }, - "strain": { - "value": "ON754985" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A27-", - "T153-", - "-595T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "SI2022_S7", - "node_attrs": { - "div": 64, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "country": { - "value": "Slovenia" - }, - "date": { - "value": "2022-06-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "SI2022_S7" - }, - "strain": { - "value": "ON838178" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G19-", - "T153-", - "-595T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A196604-" - ] - } - } - }, - { - "name": "NODE_0000208", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A27-", - "T153-", - "-595T", - "G167517A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG193": [ - "E62K" - ] - }, - "labels": { - "aa": "OPG193: E62K" - } - }, - "children": [ - { - "name": "SLO", - "node_attrs": { - "div": 65, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Skubic,C., Rozman,D., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Skubic,C., Rozman,D., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "country": { - "value": "Slovenia" - }, - "date": { - "value": "2022-05-23" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "SLO" - }, - "strain": { - "value": "ON609725" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV_SI2022_S1_VEROE6", - "node_attrs": { - "div": 65, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "country": { - "value": "Slovenia" - }, - "date": { - "value": "2022-05-23" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV_SI2022_S1_VEROE6" - }, - "strain": { - "value": "ON754987" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000209", - "node_attrs": { - "div": 67, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G101152A", - "G124855T", - "G141131A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG145": [ - "E303D" - ] - }, - "labels": { - "aa": "OPG145: E303D" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI371", - "node_attrs": { - "div": 68, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI371" - }, - "strain": { - "value": "OP484692" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C180490G" - ] - } - } - }, - { - "name": "9000409", - "node_attrs": { - "div": 67, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "country": { - "value": "United Kingdom" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "9000409" - }, - "strain": { - "value": "OP536785" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "-595T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-196602A", - "-196603A" - ] - } - } - } - ] - }, - { - "name": "NODE_0000210", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G85581A", - "G150550-", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ], - "OPG107": [ - "V24I" - ] - }, - "labels": { - "aa": "OPG107: V24I" - } - }, - "children": [ - { - "name": "NY-NYCPHL-000625", - "node_attrs": { - "div": 66, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-09-28" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000625" - }, - "strain": { - "value": "OQ419049" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G188294A" - ] - } - } - }, - { - "name": "NY-NYCPHL-000465", - "node_attrs": { - "div": 65, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-22" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000465" - }, - "strain": { - "value": "OQ468885" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000211", - "node_attrs": { - "div": 68, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C8612T", - "G52232A", - "C56018T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "G187156A" - ], - "OPG071": [ - "S736L" - ], - "OPG074": [ - "E370K" - ] - }, - "labels": { - "aa": "OPG071: S736L; OPG074: E370K" - } - }, - "children": [ - { - "name": "Slovenia-MPXV-36-2022", - "node_attrs": { - "div": 71, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "country": { - "value": "Slovenia" - }, - "date": { - "value": "2022-07-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Slovenia-MPXV-36-2022" - }, - "strain": { - "value": "OP605578" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A91-", - "C64583A", - "C115217T", - "C183631T" - ], - "OPG083": [ - "G45V" - ], - "OPG210": [ - "S759F" - ] - }, - "labels": { - "aa": "OPG083: G45V; OPG210: S759F" - } - } - }, - { - "name": "Slovenia-MPXV-40-2022", - "node_attrs": { - "div": 68, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "country": { - "value": "Slovenia" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Slovenia-MPXV-40-2022" - }, - "strain": { - "value": "OP605581" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C126-" - ] - } - } - }, - { - "name": "Slovenia-MPXV-44-2022", - "node_attrs": { - "div": 68, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "country": { - "value": "Slovenia" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Slovenia-MPXV-44-2022" - }, - "strain": { - "value": "OP605585" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000215", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C133161T", - "C157632T" - ] - } - }, - "children": [ - { - "name": "Monkeypox/PT0376/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2022-07-07" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "Monkeypox/PT0376/2022" - }, - "strain": { - "value": "OP555472" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G159243A" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_165/Belgium/2022", - "node_attrs": { - "div": 66, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-07-27" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_165/Belgium/2022" - }, - "strain": { - "value": "OR086974" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G41336A", - "T133078-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T" - ] - } - } - }, - { - "name": "NODE_0000216", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T168120C", - "A179049-", - "A179050-", - "C179051-", - "T179052-", - "G179053-", - "A179054-", - "A179055-", - "G179056-", - "T179057-", - "T179058-", - "T179059-", - "A179060-", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-", - "-179081A" - ], - "OPG193": [ - "F263L" - ] - }, - "labels": { - "aa": "OPG193: F263L" - } - }, - "children": [ - { - "name": "MPXV/ITM_pt_16/Belgium/10-Jun-2022", - "node_attrs": { - "div": 66, - "author": { - "author": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., den Bossche,D.V., Florence,E., Rezende,A.M., Vercauteren,K., Esbroeck,M.V., Bracke,S., Brosius,I., Soentjens,P.", - "value": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., den Bossche,D.V., Florence,E., Rezende,A.M., Vercauteren,K., Esbroeck,M.V., Bracke,S., Brosius,I., Soentjens,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-06-10" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/ITM_pt_16/Belgium/10-Jun-2022" - }, - "strain": { - "value": "OP144212" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "C146824T", - "G179020-", - "T179021-", - "C179022-", - "G179023-", - "A179024-", - "G179025-", - "T179026-", - "A179027-", - "T179028-", - "G179029-", - "A179030-", - "A179031-", - "T179032-", - "A179033-", - "C179034-", - "G179035-", - "G179036-", - "A179037-", - "G179038-", - "T179039-", - "A179040-", - "C179041-", - "A179042-", - "A179043-", - "A179044-", - "C179045-", - "A179046-", - "T179047-", - "A179048-", - "T196998-" - ] - } - } - }, - { - "name": "MPXV/ITM_pt_25/Belgium/16-Jun-2022", - "node_attrs": { - "div": 66, - "author": { - "author": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., den Bossche,D.V., Florence,E., Rezende,A.M., Vercauteren,K., Esbroeck,M.V., Bracke,S., Brosius,I., Soentjens,P.", - "value": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., den Bossche,D.V., Florence,E., Rezende,A.M., Vercauteren,K., Esbroeck,M.V., Bracke,S., Brosius,I., Soentjens,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-06-16" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/ITM_pt_25/Belgium/16-Jun-2022" - }, - "strain": { - "value": "OP144214" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000217", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G152776A" - ], - "OPG180": [ - "D29N" - ] - }, - "labels": { - "aa": "OPG180: D29N" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/ON/RKI658", - "node_attrs": { - "div": 68, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2022-08-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI658" - }, - "strain": { - "value": "OQ159053" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C43382T", - "G78448A", - "G176946A" - ], - "OPG063": [ - "V103I" - ], - "OPG205": [ - "D431N" - ] - }, - "labels": { - "aa": "OPG063: V103I; OPG205: D431N" - } - } - }, - { - "name": "MPXV/human/Taiwan/109-005210/2023", - "node_attrs": { - "div": 67, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "country": { - "value": "Taiwan" - }, - "date": { - "value": "2023-02-XX" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/human/Taiwan/109-005210/2023" - }, - "strain": { - "value": "OQ581854" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T64426C", - "G158406A", - "T192403-", - "A192404-", - "G192405-", - "A192410-" - ] - } - } - }, - { - "name": "NODE_0000218", - "node_attrs": { - "div": 76, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C15969T", - "C17998T", - "G40610A", - "C43803T", - "C63879T", - "G70190A", - "G118289A", - "C147011T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C159532T", - "G161629A", - "C189427T" - ], - "OPG005": [ - "P77S" - ], - "OPG027": [ - "E137K" - ], - "OPG031": [ - "M277I" - ], - "OPG064": [ - "G699E" - ], - "OPG083": [ - "D280N" - ], - "OPG089": [ - "E109K" - ], - "OPG185": [ - "P206S" - ], - "OPG188": [ - "E12K" - ] - }, - "labels": { - "aa": "OPG005: P77S; OPG027: E137K; OPG031: M277I; OPG064: G699E; OPG083: D280N; OPG089: E109K; OPG185: P206S; OPG188: E12K" - } - }, - "children": [ - { - "name": "MPXV/Germany/2023/RKI718", - "node_attrs": { - "div": 76, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2023-01-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2023/RKI718" - }, - "strain": { - "value": "OQ451903" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Germany/2023/RKI719", - "node_attrs": { - "div": 76, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "country": { - "value": "Germany" - }, - "date": { - "value": "2023-01-XX" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/Germany/2023/RKI719" - }, - "strain": { - "value": "OQ451904" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000219", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150567T", - "C170673T", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "A196715G" - ] - } - }, - "children": [ - { - "name": "NY-NYCPHL-000766", - "node_attrs": { - "div": 65, - "author": { - "author": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2022-07-12" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-000766" - }, - "strain": { - "value": "OQ468649" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T" - ] - } - } - }, - { - "name": "NODE_0000220", - "node_attrs": { - "div": 75, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C19558T", - "G32277A", - "C35688T", - "G39140A", - "G55059A", - "G75512A", - "C110402T", - "C121161T", - "G150550-", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "C179542T", - "C189174T" - ], - "NBT03_gp052": [ - "S28L" - ], - "OPG034": [ - "E150K" - ], - "OPG049": [ - "S292L" - ], - "OPG095": [ - "R237K" - ], - "OPG139": [ - "A70T" - ] - }, - "labels": { - "aa": "NBT03_gp052: S28L; OPG034: E150K; OPG049: S292L; OPG095: R237K; OPG139: A70T" - } - }, - "children": [ - { - "name": "NY-NYCPHL-001190", - "node_attrs": { - "div": 75, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-01-11" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-001190" - }, - "strain": { - "value": "OQ419090" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NY-NYCPHL-001191", - "node_attrs": { - "div": 77, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-01-11" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "NY-NYCPHL-001191" - }, - "strain": { - "value": "OQ419091" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C134545T", - "C138212T" - ], - "OPG155": [ - "E94K" - ] - }, - "labels": { - "aa": "OPG155: E94K" - } - } - }, - { - "name": "B1221136", - "node_attrs": { - "div": 75, - "author": { - "author": "Miller,H., Bajwa,M.", - "value": "Miller,H., Bajwa,M." - }, - "country": { - "value": "USA" - }, - "date": { - "value": "2023-03-13" - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Delaware Public Health Lab, Sequencing/Bioinformatics" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "B1221136" - }, - "strain": { - "value": "OR134560" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "B.1.3" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150550G", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000221", - "node_attrs": { - "div": 65, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G105923A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG124": [ - "L16F" - ] - }, - "labels": { - "aa": "OPG124: L16F", - "clade": "C.1" - } - }, - "children": [ - { - "name": "MPXV/human/Japan/Tokyo/2022/TKY220176", - "node_attrs": { - "div": 65, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "country": { - "value": "Japan" - }, - "date": { - "value": "2022-10-XX" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2022/TKY220176" - }, - "strain": { - "value": "LC753969" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/human/Taiwan/110-093831/2023", - "node_attrs": { - "div": 67, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "country": { - "value": "Taiwan" - }, - "date": { - "value": "2023-02-XX" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/human/Taiwan/110-093831/2023" - }, - "strain": { - "value": "OQ581853" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T132513C", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "C185069T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_122", - "node_attrs": { - "div": 66, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "country": { - "value": "Belgium" - }, - "date": { - "value": "2022-10-28" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_122" - }, - "strain": { - "value": "OR035728" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133078-", - "G149818A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "-179093T", - "-179094T", - "-179095A", - "-179096T", - "-179097A", - "-179098T", - "-179099A", - "-179100C", - "-179101A", - "-179102T", - "-179103T", - "-179104A", - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG176": [ - "D4N" - ] - }, - "labels": { - "aa": "OPG176: D4N" - } - } - }, - { - "name": "MPXV/human/Japan/Tokyo/2022/TKY220165", - "node_attrs": { - "div": 65, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "country": { - "value": "Japan" - }, - "date": { - "value": "2022-09-XX" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2022/TKY220165" - }, - "strain": { - "value": "LC753968" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/human/Japan/Tokyo/2022/TKY220187", - "node_attrs": { - "div": 65, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "country": { - "value": "Japan" - }, - "date": { - "value": "2022-10-XX" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2022/TKY220187" - }, - "strain": { - "value": "LC753970" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000223", - "node_attrs": { - "div": 66, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C3987T" - ] - } - }, - "children": [ - { - "name": "MPXV/human/Taiwan/110-539498/2023", - "node_attrs": { - "div": 71, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "country": { - "value": "Taiwan" - }, - "date": { - "value": "2023-03-XX" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/human/Taiwan/110-539498/2023" - }, - "strain": { - "value": "OQ721954" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C798T", - "C11923T", - "T14737C", - "C48442T", - "G90825A", - "G102694A", - "-179077A", - "-179078T", - "-179079A", - "-179080T", - "-179081A", - "-179082C", - "-179083A", - "-179084T", - "-179085T", - "-179086A", - "-179087T", - "-179088A", - "-179089T", - "-179090A", - "-179091C", - "-179092A", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A191312G", - "G196412A" - ], - "NBT03_gp175": [ - "I87V" - ], - "OPG068": [ - "A81V" - ] - }, - "labels": { - "aa": "NBT03_gp175: I87V; OPG068: A81V" - } - } - }, - { - "name": "NODE_0000224", - "node_attrs": { - "div": 67, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C166940T", - "G193223A" - ] - } - }, - "children": [ - { - "name": "MPXV/human/Japan/Tokyo/2023/TKY220318", - "node_attrs": { - "div": 67, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "country": { - "value": "Japan" - }, - "date": { - "value": "2023-01-25" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2023/TKY220318" - }, - "strain": { - "value": "LC756923" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/human/Japan/Tokyo/2023/TKY220325", - "node_attrs": { - "div": 68, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "country": { - "value": "Japan" - }, - "date": { - "value": "2023-01-30" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2023/TKY220325" - }, - "strain": { - "value": "LC756924" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C151434T" - ] - } - } - }, - { - "name": "MPXV/human/Japan/Tokyo/2023/TKY220343", - "node_attrs": { - "div": 68, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K., Harada,S., Amano,A.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K., Harada,S., Amano,A." - }, - "country": { - "value": "Japan" - }, - "date": { - "value": "2023-02-13" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2023/TKY220343" - }, - "strain": { - "value": "LC760461" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C798T", - "C68765T", - "G196412A" - ], - "OPG086": [ - "M33I" - ] - }, - "labels": { - "aa": "OPG086: M33I" - } - } - }, - { - "name": "MPXV/human/Japan/Tokyo/2023/TKY220342", - "node_attrs": { - "div": 68, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "country": { - "value": "Japan" - }, - "date": { - "value": "2023-02-09" - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2023/TKY220342" - }, - "strain": { - "value": "LC756925" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C84734T" - ] - } - } - }, - { - "name": "NODE_0000225", - "node_attrs": { - "div": 75, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G143-", - "G144-", - "A145-", - "T146-", - "A147-", - "A148-", - "A149-", - "A150-", - "A151-", - "C152-", - "T153-", - "T154-", - "T155-", - "T156-", - "T157-", - "A158-", - "C159-", - "G160-", - "A161-", - "C162-", - "T163-", - "C164-", - "C165-", - "A166-", - "T167-", - "C168-", - "A169-", - "G170-", - "A171-", - "A172-", - "A173-", - "G174-", - "A175-", - "G176-", - "G177-", - "T178-", - "T179-", - "T180-", - "A181-", - "A182-", - "T183-", - "A184-", - "T185-", - "T186-", - "T187-", - "T188-", - "T189-", - "G190-", - "T191-", - "G192-", - "A193-", - "G194-", - "A195-", - "C196-", - "C197-", - "C198-", - "A199-", - "T200-", - "C201-", - "G202-", - "A203-", - "A204-", - "G205-", - "A206-", - "G207-", - "A208-", - "G209-", - "A210-", - "A211-", - "A212-", - "G213-", - "A214-", - "G215-", - "A216-", - "T217-", - "G218-", - "G219-", - "T220-", - "T221-", - "A222-", - "G223-", - "T224-", - "C225-", - "A226-", - "A227-", - "G228-", - "A229-", - "T230-", - "A231-", - "T232-", - "T233-", - "T234-", - "T235-", - "T236-", - "C237-", - "T238-", - "T239-", - "A240-", - "G241-", - "T242-", - "A243-", - "C244-", - "A245-", - "A246-", - "A247-", - "A248-", - "G249-", - "T250-", - "C251-", - "A252-", - "A253-", - "T254-", - "G255-", - "T256-", - "T257-", - "T258-", - "T259-", - "A260-", - "A261-", - "A262-", - "A263-", - "T264-", - "A265-", - "T266-", - "A267-", - "T268-", - "G269-", - "G270-", - "A271-", - "C272-", - "G273-", - "A274-", - "G275-", - "A276-", - "A277-", - "T278-", - "T279-", - "A280-", - "A281-", - "T282-", - "T283-", - "T284-", - "G285-", - "T286-", - "C287-", - "T288-", - "G289-", - "T290-", - "A291-", - "T292-", - "A293-", - "A294-", - "A295-", - "A296-", - "A297-", - "C298-", - "T299-", - "T300-", - "G301-", - "T302-", - "G303-", - "T304-", - "G305-", - "A306-", - "A307-", - "A308-", - "T309-", - "T310-", - "A311-", - "T312-", - "G313-", - "T314-", - "A315-", - "C316-", - "T317-", - "A318-", - "G319-", - "A320-", - "G321-", - "A322-", - "A323-", - "A324-", - "A325-", - "A326-", - "A327-", - "C328-", - "G329-", - "T330-", - "G331-", - "A332-", - "G333-", - "C334-", - "A335-", - "G336-", - "T337-", - "G338-", - "T339-", - "C340-", - "C341-", - "C342-", - "C343-", - "T344-", - "A345-", - "C346-", - "A347-", - "T348-", - "G349-", - "G350-", - "A351-", - "T352-", - "T353-", - "T354-", - "T355-", - "A356-", - "C357-", - "A358-", - "G359-", - "A360-", - "T361-", - "C362-", - "A363-", - "T364-", - "T365-", - "T366-", - "A367-", - "T368-", - "A369-", - "T370-", - "T371-", - "C372-", - "C373-", - "A374-", - "A375-", - "A376-", - "A377-", - "A378-", - "T379-", - "A380-", - "T381-", - "T382-", - "A383-", - "A384-", - "C385-", - "T386-", - "A387-", - "T388-", - "A389-", - "T390-", - "A391-", - "C392-", - "G393-", - "T394-", - "T395-", - "T396-", - "A397-", - "T398-", - "T399-", - "A400-", - "T401-", - "A402-", - "T403-", - "G404-", - "A405-", - "T406-", - "G407-", - "T408-", - "T409-", - "A410-", - "A411-", - "C412-", - "G413-", - "T414-", - "G415-", - "T416-", - "A417-", - "A418-", - "A419-", - "T420-", - "T421-", - "A422-", - "T423-", - "A424-", - "A425-", - "A426-", - "C427-", - "A428-", - "T429-", - "T430-", - "A431-", - "T432-", - "T433-", - "T434-", - "T435-", - "A436-", - "T437-", - "G438-", - "A439-", - "T440-", - "G441-", - "C442-", - "A443-", - "A444-", - "T445-", - "T446-", - "G447-", - "T448-", - "C449-", - "T450-", - "G451-", - "A452-", - "C453-", - "A454-", - "A455-", - "C456-", - "C457-", - "T458-", - "A459-", - "G460-", - "A461-", - "T462-", - "T463-", - "G464-", - "G465-", - "T466-", - "A467-", - "T468-", - "A469-", - "A470-", - "G471-", - "G472-", - "A473-", - "T474-", - "G475-", - "T476-", - "T477-", - "G478-", - "A479-", - "T480-", - "A481-", - "A482-", - "G483-", - "C484-", - "T485-", - "C486-", - "T487-", - "A488-", - "C489-", - "G490-", - "A491-", - "G492-", - "A493-", - "A494-", - "T495-", - "A496-", - "T497-", - "A498-", - "T499-", - "T500-", - "G501-", - "T502-", - "T503-", - "G504-", - "G505-", - "A506-", - "C507-", - "G508-", - "T509-", - "T510-", - "A511-", - "T512-", - "C513-", - "G514-", - "T515-", - "T516-", - "T517-", - "A518-", - "C519-", - "G520-", - "A521-", - "A522-", - "A523-", - "T524-", - "A525-", - "G526-", - "T527-", - "T528-", - "G529-", - "A530-", - "G531-", - "A532-", - "C533-", - "A534-", - "T535-", - "C536-", - "A539-", - "A540-", - "A541-", - "G542-", - "G544-", - "G545-", - "T546-", - "T547-", - "T548-", - "A549-", - "A550-", - "T551-", - "A552-", - "T553-", - "T554-", - "T555-", - "T557-", - "G558-", - "G560-", - "A561-", - "G562-", - "C564-", - "A566-", - "T567-", - "G572-", - "G580-", - "G582-", - "G13563A", - "C21062T", - "G101241A", - "C149963T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G152866A", - "G184562A", - "G188348A", - "C188946T", - "G191028-", - "C191029-", - "G191030-", - "A191031-", - "A191032-", - "T191033-", - "A191034-", - "A191035-", - "G191036-", - "A191037-", - "C191038-", - "A191039-", - "G191040-", - "T191041-", - "G191042-", - "C191043-", - "G191044-", - "A191045-", - "T191046-", - "T191047-", - "C191048-", - "G191049-", - "C191050-", - "A191051-", - "C191052-", - "C191053-", - "A191054-", - "T191055-", - "G191056-", - "G191057-", - "A191058-", - "G191059-", - "T191060-", - "C191061-", - "G191062-", - "G191063-", - "T191064-", - "A191065-", - "G191066-", - "A191067-", - "T191068-", - "T191069-", - "T191070-", - "C191071-", - "A191072-", - "T191073-", - "G191074-", - "G191075-", - "C191076-", - "T191077-", - "G191078-", - "T191079-", - "C191080-", - "G191081-", - "A191082-", - "T191083-", - "G191084-", - "A191085-", - "G191086-", - "C191087-", - "A191088-", - "G191089-", - "T191090-", - "T191091-", - "T191092-", - "C191093-", - "A191094-", - "C191095-", - "G191096-", - "A191097-", - "C191098-", - "G191099-", - "A191100-", - "C191101-", - "C191102-", - "T191103-", - "C191104-" - ], - "NBT03_gp175": [ - "M1-", - "E2-", - "S3-", - "V4-", - "D5-", - "F6-", - "M7-", - "A8-", - "V9-", - "D10-", - "E11-", - "Q12-", - "F13-", - "H14-", - "D15-", - "D16-", - "L17-" - ], - "OPG025": [ - "P569S" - ], - "OPG036": [ - "M1I" - ], - "OPG176": [ - "S52L" - ], - "OPG180": [ - "D59N" - ] - }, - "labels": { - "aa": "NBT03_gp175: M1-, E2-, S3-, V4-, D5-, F6-, M7-, A8-, V9-, D10-, E11-, Q12-, F13-, H14-, D15-, D16-, L17-; OPG025: P569S; OPG036: M1I; OPG176: S52L; OPG180: D59N" - } - }, - "children": [ - { - "name": "MPXV/PT0629/2023", - "node_attrs": { - "div": 75, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2023-06-20" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/PT0629/2023" - }, - "strain": { - "value": "OR326993" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/PT0631/2023", - "node_attrs": { - "div": 78, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "country": { - "value": "Portugal" - }, - "date": { - "value": "2023-06-22" - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "clade_membership": { - "value": "IIb" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain_original": { - "value": "MPXV/PT0631/2023" - }, - "strain": { - "value": "OR326995" - }, - "host": { - "value": "Homo sapiens" - }, - "lineage": { - "value": "C.1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A537-", - "G538-", - "A543-", - "T556-", - "T559-", - "A563-", - "C565-", - "C568-", - "G569-", - "A570-", - "A571-", - "A573-", - "G574-", - "A575-", - "G576-", - "A577-", - "A578-", - "A579-", - "A581-", - "A583-", - "A584-", - "T585-", - "C34435T", - "C37738T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G151847A", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-", - "A190988-", - "G190989-", - "G190990-", - "A190991-", - "A190992-", - "A190993-", - "A190994-", - "C190995-", - "A190996-", - "T190997-", - "G190998-", - "T190999-", - "A191000-", - "C191001-", - "A191002-", - "T191003-", - "A191004-", - "A191005-", - "T191006-", - "T191007-", - "A191008-", - "T191009-", - "A191010-", - "A191011-", - "A191012-", - "A191013-", - "A191014-", - "A191015-", - "T191016-", - "G191017-", - "A191018-", - "A191019-", - "A191020-", - "A191021-", - "T191022-", - "C191023-", - "A191024-", - "A191025-", - "T191026-", - "G191027-", - "-191065A", - "-191066G", - "A196514-", - "C196515-" - ], - "NBT03_gp175": [ - "-4X", - "-5X", - "*438X" - ], - "OPG053": [ - "A86T" - ], - "OPG056": [ - "E433K" - ] - }, - "labels": { - "aa": "NBT03_gp175: -4X, -5X, *438X; OPG053: A86T; OPG056: E433K" - } - } - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } -} diff --git a/data/nextstrain/mpx/mpxv/ancestral/CHANGELOG.md b/data/nextstrain/mpx/mpxv/ancestral/CHANGELOG.md deleted file mode 100644 index 04463a94..00000000 --- a/data/nextstrain/mpx/mpxv/ancestral/CHANGELOG.md +++ /dev/null @@ -1,7 +0,0 @@ -## Unreleased - -Initial release for Nextclade v3! - -This dataset is converted from the corresponding older dataset for Nextclade v2. You can find old versions of datasets here: https://github.com/nextstrain/nextclade_data/tree/2023-08-17--15-51-24--UTC/data/datasets - -Read more about Nextclade datasets in the documentation: https://docs.nextstrain.org/projects/nextclade/en/stable/user/datasets.html diff --git a/data/nextstrain/mpx/mpxv/ancestral/README.md b/data/nextstrain/mpx/mpxv/ancestral/README.md deleted file mode 100644 index 0e35ea6b..00000000 --- a/data/nextstrain/mpx/mpxv/ancestral/README.md +++ /dev/null @@ -1,14 +0,0 @@ -# Nextclade dataset for "Monkeypox (All Clades)" based on reference "Reconstructed ancestral MPXV" (MPXV/ancestral) - - -## Dataset attributes - -| attribute | value | value friendly | -| -------------------- | -------------------- | ---------------------------------------- | -| name | MPXV | Monkeypox (All Clades) | -| reference | ancestral | Reconstructed ancestral MPXV | - - -## What is Nextclade dataset - -Read more about Nextclade datasets in Nextclade documentation: https://docs.nextstrain.org/projects/nextclade/en/stable/user/datasets.html diff --git a/data/nextstrain/mpx/mpxv/ancestral/genome_annotation.gff3 b/data/nextstrain/mpx/mpxv/ancestral/genome_annotation.gff3 deleted file mode 100644 index 32348669..00000000 --- a/data/nextstrain/mpx/mpxv/ancestral/genome_annotation.gff3 +++ /dev/null @@ -1,361 +0,0 @@ -##sequence-region NC_063383.1 1 197209 -##species https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10244 -##NC_063383.1 RefSeq region 1 197209 . + . ID=NC_063383.1:1..197209;Dbxref=taxon:10244;collection-date=2018-08;country=Nigeria: Rivers State;gbkey=Src;genome=genomic;genotype=West African clade;isolate=MPXV-M5312_HM12_Rivers;mol_type=genomic DNA;nat-host=Homo sapiens -## Required edit of above line for augur translate -NC_063383.1 RefSeq source 1 197209 . + . gene_name=nuc;ID=NC_063383.1:1..197209;Dbxref=taxon:10244;collection-date=2018-08;country=Nigeria: Rivers State;gbkey=Src;genome=genomic;genotype=West African clade;isolate=MPXV-M5312_HM12_Rivers;mol_type=genomic DNA;nat-host=Homo sapiens -NC_063383.1 RefSeq gene 835 1575 . - . ID=gene-NBT03_gp001;Dbxref=GeneID:72551607;Name=OPG001;gbkey=Gene;gene_name=OPG001;gene_biotype=protein_coding;locus_tag=NBT03_gp001;old_locus_tag=MPXV-M5312_HM12_Rivers-001 -NC_063383.1 RefSeq CDS 835 1575 . - 0 ID=cds-YP_010377002.1;Parent=gene-NBT03_gp001;Dbxref=Genbank:YP_010377002.1,GeneID:72551607;Name=YP_010377002.1;Note=J1L%3B similar to Vaccinia virus strain Copenhagen C23L%3B most abundant secreted protein%3B CC-chemokine binding;gbkey=CDS;gene_name=OPG001;locus_tag=NBT03_gp001;product=MPXVgp001;protein_id=YP_010377002.1 -NC_063383.1 RefSeq gene 1702 2751 . - . ID=gene-NBT03_gp002;Dbxref=GeneID:72551418;Name=OPG002;gbkey=Gene;gene_name=OPG002;gene_biotype=protein_coding;locus_tag=NBT03_gp002;old_locus_tag=MPXV-M5312_HM12_Rivers-002 -NC_063383.1 RefSeq CDS 1702 2751 . - 0 ID=cds-YP_010377003.1;Parent=gene-NBT03_gp002;Dbxref=Genbank:YP_010377003.1,GeneID:72551418;Name=YP_010377003.1;Note=J2L;gbkey=CDS;gene_name=OPG002;locus_tag=NBT03_gp002;product=MPXVgp002;protein_id=YP_010377003.1 -NC_063383.1 RefSeq gene 2841 4607 . - . ID=gene-NBT03_gp003;Dbxref=GeneID:72551419;Name=OPG003;gbkey=Gene;gene_name=OPG003;gene_biotype=protein_coding;locus_tag=NBT03_gp003;old_locus_tag=MPXV-M5312_HM12_Rivers-003 -NC_063383.1 RefSeq CDS 2841 4607 . - 0 ID=cds-YP_010377004.1;Parent=gene-NBT03_gp003;Dbxref=Genbank:YP_010377004.1,GeneID:72551419;Name=YP_010377004.1;Note=J3L;gbkey=CDS;gene_name=OPG003;locus_tag=NBT03_gp003;product=MPXVgp003;protein_id=YP_010377004.1 -NC_063383.1 RefSeq gene 4843 6156 . - . ID=gene-NBT03_gp004;Dbxref=GeneID:72551420;Name=OPG015;gbkey=Gene;gene_name=OPG015;gene_biotype=protein_coding;locus_tag=NBT03_gp004;old_locus_tag=MPXV-M5312_HM12_Rivers-004 -NC_063383.1 RefSeq CDS 4843 6156 . - 0 ID=cds-YP_010377005.1;Parent=gene-NBT03_gp004;Dbxref=Genbank:YP_010377005.1,GeneID:72551420;Name=YP_010377005.1;Note=D1L;gbkey=CDS;gene_name=OPG015;locus_tag=NBT03_gp004;product=MPXVgp004;protein_id=YP_010377005.1 -NC_063383.1 RefSeq gene 7580 8008 . + . ID=gene-NBT03_gp005;Dbxref=GeneID:72551421;Name=OPG019;gbkey=Gene;gene_name=OPG019;gene_biotype=protein_coding;locus_tag=NBT03_gp005;old_locus_tag=MPXV-M5312_HM12_Rivers-006 -NC_063383.1 RefSeq CDS 7580 8008 . + 0 ID=cds-YP_010377006.1;Parent=gene-NBT03_gp005;Dbxref=Genbank:YP_010377006.1,GeneID:72551421;Name=YP_010377006.1;Note=D3R%3B similar to Vaccinia virus strain Copenhagen C11R%3B secreted growth factor;gbkey=CDS;gene_name=OPG019;locus_tag=NBT03_gp005;product=MPXVgp006;protein_id=YP_010377006.1 -NC_063383.1 RefSeq gene 9587 10315 . + . ID=gene-NBT03_gp006;Dbxref=GeneID:72551422;Name=OPG021;gbkey=Gene;gene_name=OPG021;gene_biotype=protein_coding;locus_tag=NBT03_gp006;old_locus_tag=MPXV-M5312_HM12_Rivers-008 -NC_063383.1 RefSeq CDS 9587 10315 . + 0 ID=cds-YP_010377007.1;Parent=gene-NBT03_gp006;Dbxref=Genbank:YP_010377007.1,GeneID:72551422;Name=YP_010377007.1;Note=D5R%3B zinc binding%3B virosome localization%3B virulence factor%3B inhibition of apoptosis induced by UV irradiation;gbkey=CDS;gene_name=OPG021;locus_tag=NBT03_gp006;product=MPXVgp008;protein_id=YP_010377007.1 -NC_063383.1 RefSeq gene 10478 10858 . - . ID=gene-NBT03_gp007;Dbxref=GeneID:72551423;Name=OPG022;gbkey=Gene;gene_name=OPG022;gene_biotype=protein_coding;locus_tag=NBT03_gp007;old_locus_tag=MPXV-M5312_HM12_Rivers-009 -NC_063383.1 RefSeq CDS 10478 10858 . - 0 ID=cds-YP_010377008.1;Parent=gene-NBT03_gp007;Dbxref=Genbank:YP_010377008.1,GeneID:72551423;Name=YP_010377008.1;Note=D6L%3B secreted IL-18 binding protein;gbkey=CDS;gene_name=OPG022;locus_tag=NBT03_gp007;product=MPXVgp009;protein_id=YP_010377008.1 -NC_063383.1 RefSeq gene 10918 12900 . - . ID=gene-NBT03_gp008;Dbxref=GeneID:72551424;Name=OPG023;gbkey=Gene;gene_name=OPG023;gene_biotype=protein_coding;locus_tag=NBT03_gp008;old_locus_tag=MPXV-M5312_HM12_Rivers-010 -NC_063383.1 RefSeq CDS 10918 12900 . - 0 ID=cds-YP_010377009.1;Parent=gene-NBT03_gp008;Dbxref=Genbank:YP_010377009.1,GeneID:72551424;Name=YP_010377009.1;Note=D7L%3B host range%3B ankyrin-like;gbkey=CDS;gene_name=OPG023;locus_tag=NBT03_gp008;product=MPXVgp010;protein_id=YP_010377009.1 -NC_063383.1 RefSeq gene 13034 13228 . - . ID=gene-NBT03_gp009;Dbxref=GeneID:72551425;Name=OPG024;gbkey=Gene;gene_name=OPG024;gene_biotype=protein_coding;locus_tag=NBT03_gp009;old_locus_tag=MPXV-M5312_HM12_Rivers-011 -NC_063383.1 RefSeq CDS 13034 13228 . - 0 ID=cds-YP_010377010.1;Parent=gene-NBT03_gp009;Dbxref=Genbank:YP_010377010.1,GeneID:72551425;Name=YP_010377010.1;Note=D8L;gbkey=CDS;gene_name=OPG024;locus_tag=NBT03_gp009;product=MPXVgp011;protein_id=YP_010377010.1 -NC_063383.1 RefSeq gene 13375 15267 . - . ID=gene-NBT03_gp010;Dbxref=GeneID:72551426;Name=OPG025;gbkey=Gene;gene_name=OPG025;gene_biotype=protein_coding;locus_tag=NBT03_gp010;old_locus_tag=MPXV-M5312_HM12_Rivers-012 -NC_063383.1 RefSeq CDS 13375 15267 . - 0 ID=cds-YP_010377011.1;Parent=gene-NBT03_gp010;Dbxref=Genbank:YP_010377011.1,GeneID:72551426;Name=YP_010377011.1;Note=D9L%3B similar to Vaccinia virus strain Copenhagen C9L%3B ankyrin-like;gbkey=CDS;gene_name=OPG025;locus_tag=NBT03_gp010;product=MPXVgp012;protein_id=YP_010377011.1 -NC_063383.1 RefSeq gene 15925 16377 . - . ID=gene-NBT03_gp011;Dbxref=GeneID:72551427;Name=OPG027;gbkey=Gene;gene_name=OPG027;gene_biotype=protein_coding;locus_tag=NBT03_gp011;old_locus_tag=MPXV-M5312_HM12_Rivers-013 -NC_063383.1 RefSeq CDS 15925 16377 . - 0 ID=cds-YP_010377012.1;Parent=gene-NBT03_gp011;Dbxref=Genbank:YP_010377012.1,GeneID:72551427;Name=YP_010377012.1;Note=D10L%3B similar to Vaccinia virus strain Copenhagen C7L%3B host range;gbkey=CDS;gene_name=OPG027;locus_tag=NBT03_gp011;product=MPXVgp013;protein_id=YP_010377012.1 -NC_063383.1 RefSeq gene 16602 17069 . - . ID=gene-NBT03_gp012;Dbxref=GeneID:72551428;Name=OPG029;gbkey=Gene;gene_name=OPG029;gene_biotype=protein_coding;locus_tag=NBT03_gp012;old_locus_tag=MPXV-M5312_HM12_Rivers-014 -NC_063383.1 RefSeq CDS 16602 17069 . - 0 ID=cds-YP_010377013.1;Parent=gene-NBT03_gp012;Dbxref=Genbank:YP_010377013.1,GeneID:72551428;Name=YP_010377013.1;Note=D11L%3B similar to Vaccinia virus strain Copenhagen C6L;gbkey=CDS;gene_name=OPG029;locus_tag=NBT03_gp012;product=MPXVgp014;protein_id=YP_010377013.1 -NC_063383.1 RefSeq gene 17213 17833 . - . ID=gene-NBT03_gp013;Dbxref=GeneID:72551429;Name=OPG030;gbkey=Gene;gene_name=OPG030;gene_biotype=protein_coding;locus_tag=NBT03_gp013;old_locus_tag=MPXV-M5312_HM12_Rivers-015 -NC_063383.1 RefSeq CDS 17213 17833 . - 0 ID=cds-YP_010377014.1;Parent=gene-NBT03_gp013;Dbxref=Genbank:YP_010377014.1,GeneID:72551429;Name=YP_010377014.1;Note=D12L%3B similar to Vaccinia virus strain Copenhagen C5L%3B BTB domain of kelch-like protein;gbkey=CDS;gene_name=OPG030;locus_tag=NBT03_gp013;product=MPXVgp015;protein_id=YP_010377014.1 -NC_063383.1 RefSeq gene 17878 18828 . - . ID=gene-NBT03_gp014;Dbxref=GeneID:72551430;Name=OPG031;gbkey=Gene;gene_name=OPG031;gene_biotype=protein_coding;locus_tag=NBT03_gp014;old_locus_tag=MPXV-M5312_HM12_Rivers-016 -NC_063383.1 RefSeq CDS 17878 18828 . - 0 ID=cds-YP_010377015.1;Parent=gene-NBT03_gp014;Dbxref=Genbank:YP_010377015.1,GeneID:72551430;Name=YP_010377015.1;Note=D13L%3B similar to Vaccinia virus strain Copenhagen C4L;gbkey=CDS;gene_name=OPG031;locus_tag=NBT03_gp014;product=MPXVgp016;protein_id=YP_010377015.1 -NC_063383.1 RefSeq gene 19361 20005 . - . ID=gene-NBT03_gp015;Dbxref=GeneID:72551431;Name=OPG034;gbkey=Gene;gene_name=OPG034;gene_biotype=protein_coding;locus_tag=NBT03_gp015;old_locus_tag=MPXV-M5312_HM12_Rivers-018 -NC_063383.1 RefSeq CDS 19361 20005 . - 0 ID=cds-YP_010377017.1;Parent=gene-NBT03_gp015;Dbxref=Genbank:YP_010377017.1,GeneID:72551431;Name=YP_010377017.1;Note=D19L%3B similar to Vaccinia virus strain Copenhagen C1L;gbkey=CDS;gene_name=OPG034;locus_tag=NBT03_gp015;product=MPXVgp022;protein_id=YP_010377017.1 -NC_063383.1 RefSeq gene 20051 20404 . - . ID=gene-NBT03_gp016;Dbxref=GeneID:72551432;Name=OPG035;gbkey=Gene;gene_name=OPG035;gene_biotype=protein_coding;locus_tag=NBT03_gp016;old_locus_tag=MPXV-M5312_HM12_Rivers-019 -NC_063383.1 RefSeq CDS 20051 20404 . - 0 ID=cds-YP_010377018.1;Parent=gene-NBT03_gp016;Dbxref=Genbank:YP_010377018.1,GeneID:72551432;Name=YP_010377018.1;Note=P1L%3B similar to Vaccinia virus strain Copenhagen N1L%3B secreted virulence factor;gbkey=CDS;gene_name=OPG035;locus_tag=NBT03_gp016;product=MPXVgp023;protein_id=YP_010377018.1 -NC_063383.1 RefSeq gene 20531 21064 . - . ID=gene-NBT03_gp017;Dbxref=GeneID:72551433;Name=OPG036;gbkey=Gene;gene_name=OPG036;gene_biotype=protein_coding;locus_tag=NBT03_gp017;old_locus_tag=MPXV-M5312_HM12_Rivers-020 -NC_063383.1 RefSeq CDS 20531 21064 . - 0 ID=cds-YP_010377019.1;Parent=gene-NBT03_gp017;Dbxref=Genbank:YP_010377019.1,GeneID:72551433;Name=YP_010377019.1;Note=P2L%3B similar to Vaccinia virus strain Copenhagen N2L;gbkey=CDS;gene_name=OPG036;locus_tag=NBT03_gp017;product=MPXVgp024;protein_id=YP_010377019.1 -NC_063383.1 RefSeq gene 21105 22433 . - . ID=gene-NBT03_gp018;Dbxref=GeneID:72551434;Name=OPG037;gbkey=Gene;gene_name=OPG037;gene_biotype=protein_coding;locus_tag=NBT03_gp018;old_locus_tag=MPXV-M5312_HM12_Rivers-021 -NC_063383.1 RefSeq CDS 21105 22433 . - 0 ID=cds-YP_010377020.1;Parent=gene-NBT03_gp018;Dbxref=Genbank:YP_010377020.1,GeneID:72551434;Name=YP_010377020.1;Note=O1L%3B similar to Vaccinia virus strain Copenhagen M1L%3B ankyrin-like;gbkey=CDS;gene_name=OPG037;locus_tag=NBT03_gp018;product=MPXVgp025;protein_id=YP_010377020.1 -NC_063383.1 RefSeq gene 22497 23159 . - . ID=gene-NBT03_gp019;Dbxref=GeneID:72551435;Name=OPG038;gbkey=Gene;gene_name=OPG038;gene_biotype=protein_coding;locus_tag=NBT03_gp019;old_locus_tag=MPXV-M5312_HM12_Rivers-022 -NC_063383.1 RefSeq CDS 22497 23159 . - 0 ID=cds-YP_010377021.1;Parent=gene-NBT03_gp019;Dbxref=Genbank:YP_010377021.1,GeneID:72551435;Name=YP_010377021.1;Note=O2L%3B similar to Vaccinia virus strain Copenhagen M2L;gbkey=CDS;gene_name=OPG038;locus_tag=NBT03_gp019;product=MPXVgp026;protein_id=YP_010377021.1 -NC_063383.1 RefSeq gene 23264 24118 . - . ID=gene-NBT03_gp020;Dbxref=GeneID:72551436;Name=OPG039;gbkey=Gene;gene_name=OPG039;gene_biotype=protein_coding;locus_tag=NBT03_gp020;old_locus_tag=MPXV-M5312_HM12_Rivers-023 -NC_063383.1 RefSeq CDS 23264 24118 . - 0 ID=cds-YP_010377022.1;Parent=gene-NBT03_gp020;Dbxref=Genbank:YP_010377022.1,GeneID:72551436;Name=YP_010377022.1;Note=C1L%3B similar to Vaccinia virus strain Copenhagen K1L%3B host range%3B ankyrin-like;gbkey=CDS;gene_name=OPG039;locus_tag=NBT03_gp020;product=MPXVgp027;protein_id=YP_010377022.1 -NC_063383.1 RefSeq gene 24351 25478 . - . ID=gene-NBT03_gp021;Dbxref=GeneID:72551437;Name=OPG040;gbkey=Gene;gene_name=OPG040;gene_biotype=protein_coding;locus_tag=NBT03_gp021;old_locus_tag=MPXV-M5312_HM12_Rivers-024 -NC_063383.1 RefSeq CDS 24351 25478 . - 0 ID=cds-YP_010377023.1;Parent=gene-NBT03_gp021;Dbxref=Genbank:YP_010377023.1,GeneID:72551437;Name=YP_010377023.1;Note=SPI-3%3B C2L%3B similar to Vaccinia virus strain Copenhagen K2L%3B serine protease inhibitor-like%2C SPI-3%3B inhibition of the ability of infected cells to fuse;gbkey=CDS;gene_name=OPG040;locus_tag=NBT03_gp021;product=MPXVgp028;protein_id=YP_010377023.1 -NC_063383.1 RefSeq gene 25823 27097 . - . ID=gene-NBT03_gp022;Dbxref=GeneID:72551438;Name=OPG042;gbkey=Gene;gene_name=OPG042;gene_biotype=protein_coding;locus_tag=NBT03_gp022;old_locus_tag=MPXV-M5312_HM12_Rivers-026 -NC_063383.1 RefSeq CDS 25823 27097 . - 0 ID=cds-YP_010377025.1;Parent=gene-NBT03_gp022;Dbxref=Genbank:YP_010377025.1,GeneID:72551438;Name=YP_010377025.1;Note=C4L%3B similar to Vaccinia virus strain Copenhagen K4L%3B phospholipase D-like;gbkey=CDS;gene_name=OPG042;locus_tag=NBT03_gp022;product=MPXVgp030;protein_id=YP_010377025.1 -NC_063383.1 RefSeq gene 27125 27955 . - . ID=gene-NBT03_gp023;Dbxref=GeneID:72551439;Name=OPG043;gbkey=Gene;gene_name=OPG043;gene_biotype=protein_coding;locus_tag=NBT03_gp023;old_locus_tag=MPXV-M5312_HM12_Rivers-027 -NC_063383.1 RefSeq CDS 27125 27955 . - 0 ID=cds-YP_010377026.1;Parent=gene-NBT03_gp023;Dbxref=Genbank:YP_010377026.1,GeneID:72551439;Name=YP_010377026.1;Note=C5L%3B lysophospholipase-like;gbkey=CDS;gene_name=OPG043;locus_tag=NBT03_gp023;product=MPXVgp031;protein_id=YP_010377026.1 -NC_063383.1 RefSeq gene 28091 28540 . + . ID=gene-NBT03_gp024;Dbxref=GeneID:72551440;Name=OPG044;gbkey=Gene;gene_name=OPG044;gene_biotype=protein_coding;locus_tag=NBT03_gp024;old_locus_tag=MPXV-M5312_HM12_Rivers-028 -NC_063383.1 RefSeq CDS 28091 28540 . + 0 ID=cds-YP_010377027.1;Parent=gene-NBT03_gp024;Dbxref=Genbank:YP_010377027.1,GeneID:72551440;Name=YP_010377027.1;Note=C6R%3B similar to Vaccinia virus strain Copenhagen K7R%3B VAC B15R-like;gbkey=CDS;gene_name=OPG044;locus_tag=NBT03_gp024;product=MPXVgp032;protein_id=YP_010377027.1 -NC_063383.1 RefSeq gene 28603 29262 . - . ID=gene-NBT03_gp025;Dbxref=GeneID:72551441;Name=OPG045;gbkey=Gene;gene_name=OPG045;gene_biotype=protein_coding;locus_tag=NBT03_gp025;old_locus_tag=MPXV-M5312_HM12_Rivers-029 -NC_063383.1 RefSeq CDS 28603 29262 . - 0 ID=cds-YP_010377028.1;Parent=gene-NBT03_gp025;Dbxref=Genbank:YP_010377028.1,GeneID:72551441;Name=YP_010377028.1;Note=C7L%3B similar to Vaccinia virus strain Copenhagen F1L;gbkey=CDS;gene_name=OPG045;locus_tag=NBT03_gp025;product=MPXVgp033;protein_id=YP_010377028.1 -NC_063383.1 RefSeq gene 29274 29729 . - . ID=gene-NBT03_gp026;Dbxref=GeneID:72551442;Name=OPG046;gbkey=Gene;gene_name=OPG046;gene_biotype=protein_coding;locus_tag=NBT03_gp026;old_locus_tag=MPXV-M5312_HM12_Rivers-030 -NC_063383.1 RefSeq CDS 29274 29729 . - 0 ID=cds-YP_010377029.1;Parent=gene-NBT03_gp026;Dbxref=Genbank:YP_010377029.1,GeneID:72551442;Name=YP_010377029.1;Note=C8L%3B similar to Vaccinia virus strain Copenhagen F2L%3B deoxyuridine triphosphatase;gbkey=CDS;gene_name=OPG046;locus_tag=NBT03_gp026;product=MPXVgp034;protein_id=YP_010377029.1 -NC_063383.1 RefSeq gene 29746 31194 . - . ID=gene-NBT03_gp027;Dbxref=GeneID:72551443;Name=OPG047;gbkey=Gene;gene_name=OPG047;gene_biotype=protein_coding;locus_tag=NBT03_gp027;old_locus_tag=MPXV-M5312_HM12_Rivers-031 -NC_063383.1 RefSeq CDS 29746 31194 . - 0 ID=cds-YP_010377030.1;Parent=gene-NBT03_gp027;Dbxref=Genbank:YP_010377030.1,GeneID:72551443;Name=YP_010377030.1;Note=C9L%3B similar to Vaccinia virus strain Copenhagen F3L%3B kelch-like;gbkey=CDS;gene_name=OPG047;locus_tag=NBT03_gp027;product=MPXVgp035;protein_id=YP_010377030.1 -NC_063383.1 RefSeq gene 31205 32164 . - . ID=gene-NBT03_gp028;Dbxref=GeneID:72551444;Name=OPG048;gbkey=Gene;gene_name=OPG048;gene_biotype=protein_coding;locus_tag=NBT03_gp028;old_locus_tag=MPXV-M5312_HM12_Rivers-032 -NC_063383.1 RefSeq CDS 31205 32164 . - 0 ID=cds-YP_010377031.1;Parent=gene-NBT03_gp028;Dbxref=Genbank:YP_010377031.1,GeneID:72551444;Name=YP_010377031.1;Note=C10L%3B similar to Vaccinia virus strain Copenhagen F4L%3B ribonucleotide reductase%2C small subunit%2C R2;gbkey=CDS;gene_name=OPG048;locus_tag=NBT03_gp028;product=MPXVgp036;protein_id=YP_010377031.1 -NC_063383.1 RefSeq gene 32195 33151 . - . ID=gene-NBT03_gp029;Dbxref=GeneID:72551445;Name=OPG049;gbkey=Gene;gene_name=OPG049;gene_biotype=protein_coding;locus_tag=NBT03_gp029;old_locus_tag=MPXV-M5312_HM12_Rivers-033 -NC_063383.1 RefSeq CDS 32195 33151 . - 0 ID=cds-YP_010377032.1;Parent=gene-NBT03_gp029;Dbxref=Genbank:YP_010377032.1,GeneID:72551445;Name=YP_010377032.1;Note=C11L%3B similar to Vaccinia virus strain Copenhagen F5L;gbkey=CDS;gene_name=OPG049;locus_tag=NBT03_gp029;product=MPXVgp037;protein_id=YP_010377032.1 -NC_063383.1 RefSeq gene 33181 33408 . - . ID=gene-NBT03_gp030;Dbxref=GeneID:72551446;Name=OPG050;gbkey=Gene;gene_name=OPG050;gene_biotype=protein_coding;locus_tag=NBT03_gp030;old_locus_tag=MPXV-M5312_HM12_Rivers-034 -NC_063383.1 RefSeq CDS 33181 33408 . - 0 ID=cds-YP_010377033.1;Parent=gene-NBT03_gp030;Dbxref=Genbank:YP_010377033.1,GeneID:72551446;Name=YP_010377033.1;Note=C12L%3B similar to Vaccinia virus strain Copenhagen F6L;gbkey=CDS;gene_name=OPG050;locus_tag=NBT03_gp030;product=MPXVgp038;protein_id=YP_010377033.1 -NC_063383.1 RefSeq gene 33425 33649 . - . ID=gene-NBT03_gp031;Dbxref=GeneID:72551447;Name=OPG051;gbkey=Gene;gene_name=OPG051;gene_biotype=protein_coding;locus_tag=NBT03_gp031;old_locus_tag=MPXV-M5312_HM12_Rivers-035 -NC_063383.1 RefSeq CDS 33425 33649 . - 0 ID=cds-YP_010377034.1;Parent=gene-NBT03_gp031;Dbxref=Genbank:YP_010377034.1,GeneID:72551447;Name=YP_010377034.1;Note=C13L%3B similar to Vaccinia virus strain Copenhagen F7L;gbkey=CDS;gene_name=OPG051;locus_tag=NBT03_gp031;product=MPXVgp039;protein_id=YP_010377034.1 -NC_063383.1 RefSeq gene 33801 33995 . - . ID=gene-NBT03_gp032;Dbxref=GeneID:72551448;Name=OPG052;gbkey=Gene;gene_name=OPG052;gene_biotype=protein_coding;locus_tag=NBT03_gp032;old_locus_tag=MPXV-M5312_HM12_Rivers-036 -NC_063383.1 RefSeq CDS 33801 33995 . - 0 ID=cds-YP_010377035.1;Parent=gene-NBT03_gp032;Dbxref=Genbank:YP_010377035.1,GeneID:72551448;Name=YP_010377035.1;Note=C14L%3B similar to Vaccinia virus strain Copenhagen F8L;gbkey=CDS;gene_name=OPG052;locus_tag=NBT03_gp032;product=MPXVgp040;protein_id=YP_010377035.1 -NC_063383.1 RefSeq gene 34052 34690 . - . ID=gene-NBT03_gp033;Dbxref=GeneID:72551449;Name=OPG053;gbkey=Gene;gene_name=OPG053;gene_biotype=protein_coding;locus_tag=NBT03_gp033;old_locus_tag=MPXV-M5312_HM12_Rivers-037 -NC_063383.1 RefSeq CDS 34052 34690 . - 0 ID=cds-YP_010377036.1;Parent=gene-NBT03_gp033;Dbxref=Genbank:YP_010377036.1,GeneID:72551449;Name=YP_010377036.1;Note=C15L%3B similar to Vaccinia virus strain Copenhagen F9L;gbkey=CDS;gene_name=OPG053;locus_tag=NBT03_gp033;product=MPXVgp041;protein_id=YP_010377036.1 -NC_063383.1 RefSeq gene 34677 35996 . - . ID=gene-NBT03_gp034;Dbxref=GeneID:72551450;Name=OPG054;gbkey=Gene;gene_name=OPG054;gene_biotype=protein_coding;locus_tag=NBT03_gp034;old_locus_tag=MPXV-M5312_HM12_Rivers-038 -NC_063383.1 RefSeq CDS 34677 35996 . - 0 ID=cds-YP_010377037.1;Parent=gene-NBT03_gp034;Dbxref=Genbank:YP_010377037.1,GeneID:72551450;Name=YP_010377037.1;Note=C16L%3B similar to Vaccinia virus strain Copenhagen F10L%3B serine;gbkey=CDS;gene_name=OPG054;locus_tag=NBT03_gp034;product=MPXVgp042;protein_id=YP_010377037.1 -NC_063383.1 RefSeq gene 36019 37083 . - . ID=gene-NBT03_gp035;Dbxref=GeneID:72551451;Name=OPG055;gbkey=Gene;gene_name=OPG055;gene_biotype=protein_coding;locus_tag=NBT03_gp035;old_locus_tag=MPXV-M5312_HM12_Rivers-039 -NC_063383.1 RefSeq CDS 36019 37083 . - 0 ID=cds-YP_010377038.1;Parent=gene-NBT03_gp035;Dbxref=Genbank:YP_010377038.1,GeneID:72551451;Name=YP_010377038.1;Note=C17L%3B similar to Vaccinia virus strain Copenhagen F11L;gbkey=CDS;gene_name=OPG055;locus_tag=NBT03_gp035;product=MPXVgp043;protein_id=YP_010377038.1 -NC_063383.1 RefSeq gene 37127 39034 . - . ID=gene-NBT03_gp036;Dbxref=GeneID:72551452;Name=OPG056;gbkey=Gene;gene_name=OPG056;gene_biotype=protein_coding;locus_tag=NBT03_gp036;old_locus_tag=MPXV-M5312_HM12_Rivers-040 -NC_063383.1 RefSeq CDS 37127 39034 . - 0 ID=cds-YP_010377039.1;Parent=gene-NBT03_gp036;Dbxref=Genbank:YP_010377039.1,GeneID:72551452;Name=YP_010377039.1;Note=C18L%3B similar to Vaccinia virus strain Copenhagen F12L%3B actin tail formation;gbkey=CDS;gene_name=OPG056;locus_tag=NBT03_gp036;product=MPXVgp044;protein_id=YP_010377039.1 -NC_063383.1 RefSeq gene 39077 40195 . - . ID=gene-NBT03_gp037;Dbxref=GeneID:72551453;Name=OPG057;gbkey=Gene;gene_name=OPG057;gene_biotype=protein_coding;locus_tag=NBT03_gp037;old_locus_tag=MPXV-M5312_HM12_Rivers-041 -NC_063383.1 RefSeq CDS 39077 40195 . - 0 ID=cds-YP_010377040.1;Parent=gene-NBT03_gp037;Dbxref=Genbank:YP_010377040.1,GeneID:72551453;Name=YP_010377040.1;Note=C19L%3B similar to Vaccinia virus strain Copenhagen F13L%3B major envelope antigen of EEV%3B wrapping of IMV to form IEV%3B phospholipase D-like;gbkey=CDS;gene_name=OPG057;locus_tag=NBT03_gp037;product=MPXVgp045;protein_id=YP_010377040.1 -NC_063383.1 RefSeq gene 40213 40434 . - . ID=gene-NBT03_gp038;Dbxref=GeneID:72551454;Name=OPG058;gbkey=Gene;gene_name=OPG058;gene_biotype=protein_coding;locus_tag=NBT03_gp038;old_locus_tag=MPXV-M5312_HM12_Rivers-042 -NC_063383.1 RefSeq CDS 40213 40434 . - 0 ID=cds-YP_010377041.1;Parent=gene-NBT03_gp038;Dbxref=Genbank:YP_010377041.1,GeneID:72551454;Name=YP_010377041.1;Note=C20L%3B similar to Vaccinia virus strain Copenhagen F14L;gbkey=CDS;gene_name=OPG058;locus_tag=NBT03_gp038;product=MPXVgp046;protein_id=YP_010377041.1 -NC_063383.1 RefSeq gene 40484 40633 . - . ID=gene-NBT03_gp039;Dbxref=GeneID:72551455;Name=OPG059;gbkey=Gene;gene_name=OPG059;gene_biotype=protein_coding;locus_tag=NBT03_gp039;old_locus_tag=MPXV-M5312_HM12_Rivers-043 -NC_063383.1 RefSeq CDS 40484 40633 . - 0 ID=cds-YP_010377042.1;Parent=gene-NBT03_gp039;Dbxref=Genbank:YP_010377042.1,GeneID:72551455;Name=YP_010377042.1;gbkey=CDS;gene_name=OPG059;locus_tag=NBT03_gp039;product=C20.5L;protein_id=YP_010377042.1 -NC_063383.1 RefSeq gene 40706 41182 . - . ID=gene-NBT03_gp040;Dbxref=GeneID:72551456;Name=OPG060;gbkey=Gene;gene_name=OPG060;gene_biotype=protein_coding;locus_tag=NBT03_gp040;old_locus_tag=MPXV-M5312_HM12_Rivers-044 -NC_063383.1 RefSeq CDS 40706 41182 . - 0 ID=cds-YP_010377043.1;Parent=gene-NBT03_gp040;Dbxref=Genbank:YP_010377043.1,GeneID:72551456;Name=YP_010377043.1;Note=C21L%3B similar to Vaccinia virus strain Copenhagen F15L;gbkey=CDS;gene_name=OPG060;locus_tag=NBT03_gp040;product=MPXVgp047;protein_id=YP_010377043.1 -NC_063383.1 RefSeq gene 41189 41884 . - . ID=gene-NBT03_gp041;Dbxref=GeneID:72551457;Name=OPG061;gbkey=Gene;gene_name=OPG061;gene_biotype=protein_coding;locus_tag=NBT03_gp041;old_locus_tag=MPXV-M5312_HM12_Rivers-045 -NC_063383.1 RefSeq CDS 41189 41884 . - 0 ID=cds-YP_010377044.1;Parent=gene-NBT03_gp041;Dbxref=Genbank:YP_010377044.1,GeneID:72551457;Name=YP_010377044.1;Note=C22L%3B similar to Vaccinia virus strain Copenhagen F16L;gbkey=CDS;gene_name=OPG061;locus_tag=NBT03_gp041;product=MPXVgp048;protein_id=YP_010377044.1 -NC_063383.1 RefSeq gene 41947 42252 . + . ID=gene-NBT03_gp042;Dbxref=GeneID:72551458;Name=OPG062;gbkey=Gene;gene_name=OPG062;gene_biotype=protein_coding;locus_tag=NBT03_gp042;old_locus_tag=MPXV-M5312_HM12_Rivers-046 -NC_063383.1 RefSeq CDS 41947 42252 . + 0 ID=cds-YP_010377045.1;Parent=gene-NBT03_gp042;Dbxref=Genbank:YP_010377045.1,GeneID:72551458;Name=YP_010377045.1;Note=C23R%3B similar to Vaccinia virus strain Copenhagen F17R%3B virion core DNA-binding phosphoprotein;gbkey=CDS;gene_name=OPG062;locus_tag=NBT03_gp042;product=MPXVgp049;protein_id=YP_010377045.1 -NC_063383.1 RefSeq gene 42249 43688 . - . ID=gene-NBT03_gp043;Dbxref=GeneID:72551459;Name=OPG063;gbkey=Gene;gene_name=OPG063;gene_biotype=protein_coding;locus_tag=NBT03_gp043;old_locus_tag=MPXV-M5312_HM12_Rivers-047 -NC_063383.1 RefSeq CDS 42249 43688 . - 0 ID=cds-YP_010377046.1;Parent=gene-NBT03_gp043;Dbxref=Genbank:YP_010377046.1,GeneID:72551459;Name=YP_010377046.1;Note=F1L%3B similar to Vaccinia virus strain Copenhagen E1L%3B poly-A polymerase%2C catalytic subunit;gbkey=CDS;gene_name=OPG063;locus_tag=NBT03_gp043;product=MPXVgp050;protein_id=YP_010377046.1 -NC_063383.1 RefSeq gene 43685 45898 . - . ID=gene-NBT03_gp044;Dbxref=GeneID:72551460;Name=OPG064;gbkey=Gene;gene_name=OPG064;gene_biotype=protein_coding;locus_tag=NBT03_gp044;old_locus_tag=MPXV-M5312_HM12_Rivers-048 -NC_063383.1 RefSeq CDS 43685 45898 . - 0 ID=cds-YP_010377047.1;Parent=gene-NBT03_gp044;Dbxref=Genbank:YP_010377047.1,GeneID:72551460;Name=YP_010377047.1;Note=F2L%3B similar to Vaccinia virus strain Copenhagen E2L;gbkey=CDS;gene_name=OPG064;locus_tag=NBT03_gp044;product=MPXVgp051;protein_id=YP_010377047.1 -NC_063383.1 RefSeq gene 46022 46483 . - . ID=gene-NBT03_gp045;Dbxref=GeneID:72551461;Name=OPG065;gbkey=Gene;gene_name=OPG065;gene_biotype=protein_coding;locus_tag=NBT03_gp045;old_locus_tag=MPXV-M5312_HM12_Rivers-049 -NC_063383.1 RefSeq CDS 46022 46483 . - 0 ID=cds-YP_010377048.1;Parent=gene-NBT03_gp045;Dbxref=Genbank:YP_010377048.1,GeneID:72551461;Name=YP_010377048.1;Note=F3L%3B similar to Vaccinia virus strain Copenhagen E3L%3B interferon resistance factor%3B two forms (25 kDa and 19 kDa) of the dsRNA-binding protein%3B inhibition of dsRNA-dependent protein kinase and 2-5A-synthet;gbkey=CDS;gene_name=OPG065;locus_tag=NBT03_gp045;product=MPXVgp052;protein_id=YP_010377048.1 -NC_063383.1 RefSeq gene 46649 47428 . - . ID=gene-NBT03_gp046;Dbxref=GeneID:72551462;Name=OPG066;gbkey=Gene;gene_name=OPG066;gene_biotype=protein_coding;locus_tag=NBT03_gp046;old_locus_tag=MPXV-M5312_HM12_Rivers-050 -NC_063383.1 RefSeq CDS 46649 47428 . - 0 ID=cds-YP_010377049.1;Parent=gene-NBT03_gp046;Dbxref=Genbank:YP_010377049.1,GeneID:72551462;Name=YP_010377049.1;Note=F4L%3B similar to Vaccinia virus strain Copenhagen E4L%3B RNA polymerase 30 kDa subunit%3B simultaneously intermediate stage promoter-specific transcription factor%2C VITF-1;gbkey=CDS;gene_name=OPG066;locus_tag=NBT03_gp046;product=MPXVgp053;protein_id=YP_010377049.1 -NC_063383.1 RefSeq gene 48201 49904 . + . ID=gene-NBT03_gp047;Dbxref=GeneID:72551463;Name=OPG068;gbkey=Gene;gene_name=OPG068;gene_biotype=protein_coding;locus_tag=NBT03_gp047;old_locus_tag=MPXV-M5312_HM12_Rivers-052 -NC_063383.1 RefSeq CDS 48201 49904 . + 0 ID=cds-YP_010377051.1;Parent=gene-NBT03_gp047;Dbxref=Genbank:YP_010377051.1,GeneID:72551463;Name=YP_010377051.1;Note=F5R%3B similar to Vaccinia virus strain Copenhagen E6R;gbkey=CDS;gene_name=OPG068;locus_tag=NBT03_gp047;product=MPXVgp054;protein_id=YP_010377051.1 -NC_063383.1 RefSeq gene 49986 50486 . + . ID=gene-NBT03_gp048;Dbxref=GeneID:72551464;Name=OPG069;gbkey=Gene;gene_name=OPG069;gene_biotype=protein_coding;locus_tag=NBT03_gp048;old_locus_tag=MPXV-M5312_HM12_Rivers-053 -NC_063383.1 RefSeq CDS 49986 50486 . + 0 ID=cds-YP_010377052.1;Parent=gene-NBT03_gp048;Dbxref=Genbank:YP_010377052.1,GeneID:72551464;Name=YP_010377052.1;Note=F6R%3B similar to Vaccinia virus strain Copenhagen E7R%3B soluble myristylated protein;gbkey=CDS;gene_name=OPG069;locus_tag=NBT03_gp048;product=MPXVgp055;protein_id=YP_010377052.1 -NC_063383.1 RefSeq gene 50590 51411 . + . ID=gene-NBT03_gp049;Dbxref=GeneID:72551465;Name=OPG070;gbkey=Gene;gene_name=OPG070;gene_biotype=protein_coding;locus_tag=NBT03_gp049;old_locus_tag=MPXV-M5312_HM12_Rivers-054 -NC_063383.1 RefSeq CDS 50590 51411 . + 0 ID=cds-YP_010377053.1;Parent=gene-NBT03_gp049;Dbxref=Genbank:YP_010377053.1,GeneID:72551465;Name=YP_010377053.1;Note=F7R%3B similar to Vaccinia virus strain Copenhagen E8R;gbkey=CDS;gene_name=OPG070;locus_tag=NBT03_gp049;product=MPXVgp056;protein_id=YP_010377053.1 -NC_063383.1 RefSeq gene 51418 54438 . - . ID=gene-NBT03_gp050;Dbxref=GeneID:72551466;Name=OPG071;gbkey=Gene;gene_name=OPG071;gene_biotype=protein_coding;locus_tag=NBT03_gp050;old_locus_tag=MPXV-M5312_HM12_Rivers-055 -NC_063383.1 RefSeq CDS 51418 54438 . - 0 ID=cds-YP_010377054.1;Parent=gene-NBT03_gp050;Dbxref=Genbank:YP_010377054.1,GeneID:72551466;Name=YP_010377054.1;Note=F8L%3B similar to Vaccinia virus strain Copenhagen E9L%3B DNA polymerase%2C catalytic subunit;gbkey=CDS;gene_name=OPG071;locus_tag=NBT03_gp050;product=MPXVgp057;protein_id=YP_010377054.1 -NC_063383.1 RefSeq gene 54470 54757 . + . ID=gene-NBT03_gp051;Dbxref=GeneID:72551467;Name=OPG072;gbkey=Gene;gene_name=OPG072;gene_biotype=protein_coding;locus_tag=NBT03_gp051;old_locus_tag=MPXV-M5312_HM12_Rivers-056 -NC_063383.1 RefSeq CDS 54470 54757 . + 0 ID=cds-YP_010377055.1;Parent=gene-NBT03_gp051;Dbxref=Genbank:YP_010377055.1,GeneID:72551467;Name=YP_010377055.1;Note=F9R%3B similar to Vaccinia virus strain Copenhagen E10R%3B protein disulfide bond-forming enzyme;gbkey=CDS;gene_name=OPG072;locus_tag=NBT03_gp051;product=MPXVgp058;protein_id=YP_010377055.1 -NC_063383.1 RefSeq gene 54752 55141 . - . ID=gene-NBT03_gp052;Dbxref=GeneID:72551468;Name=NBT03_gp052;gbkey=Gene;gene_biotype=protein_coding;locus_tag=NBT03_gp052;old_locus_tag=MPXV-M5312_HM12_Rivers-057 -NC_063383.1 RefSeq CDS 54752 55141 . - 0 ID=cds-YP_010377056.1;Parent=gene-NBT03_gp052;Dbxref=Genbank:YP_010377056.1,GeneID:72551468;Name=YP_010377056.1;Note=F10L%3B similar to Vaccinia virus strain Copenhagen E11L%3B virion core protein;gbkey=CDS;locus_tag=NBT03_gp052;product=MPXVgp059;protein_id=YP_010377056.1 -NC_063383.1 RefSeq gene 55128 57125 . - . ID=gene-NBT03_gp053;Dbxref=GeneID:72551469;Name=OPG074;gbkey=Gene;gene_name=OPG074;gene_biotype=protein_coding;locus_tag=NBT03_gp053;old_locus_tag=MPXV-M5312_HM12_Rivers-058 -NC_063383.1 RefSeq CDS 55128 57125 . - 0 ID=cds-YP_010377057.1;Parent=gene-NBT03_gp053;Dbxref=Genbank:YP_010377057.1,GeneID:72551469;Name=YP_010377057.1;Note=Q1L%3B similar to Vaccinia virus strain Copenhagen O1L;gbkey=CDS;gene_name=OPG074;locus_tag=NBT03_gp053;product=MPXVgp060;protein_id=YP_010377057.1 -NC_063383.1 RefSeq gene 57172 57498 . - . ID=gene-NBT03_gp054;Dbxref=GeneID:72551470;Name=OPG075;gbkey=Gene;gene_name=OPG075;gene_biotype=protein_coding;locus_tag=NBT03_gp054;old_locus_tag=MPXV-M5312_HM12_Rivers-059 -NC_063383.1 RefSeq CDS 57172 57498 . - 0 ID=cds-YP_010377058.1;Parent=gene-NBT03_gp054;Dbxref=Genbank:YP_010377058.1,GeneID:72551470;Name=YP_010377058.1;Note=Q2L%3B similar to Vaccinia virus strain Copenhagen O2L%3B virion-associated glutaredoxin;gbkey=CDS;gene_name=OPG075;locus_tag=NBT03_gp054;product=MPXVgp061;protein_id=YP_010377058.1 -NC_063383.1 RefSeq gene 57523 57630 . - . ID=gene-NBT03_gp055;Dbxref=GeneID:72551471;Name=OPG076;gbkey=Gene;gene_name=OPG076;gene_biotype=protein_coding;locus_tag=NBT03_gp055 -NC_063383.1 RefSeq CDS 57523 57630 . - 0 ID=cds-YP_010377183.1;Parent=gene-NBT03_gp055;Dbxref=Genbank:YP_010377183.1,GeneID:72551471;Name=YP_010377183.1;gbkey=CDS;gene_name=OPG076;locus_tag=NBT03_gp055;product=MV membrane%2C EFC component;protein_id=YP_010377183.1 -NC_063383.1 RefSeq gene 57645 58583 . - . ID=gene-NBT03_gp056;Dbxref=GeneID:72551472;Name=OPG077;gbkey=Gene;gene_name=OPG077;gene_biotype=protein_coding;locus_tag=NBT03_gp056;old_locus_tag=MPXV-M5312_HM12_Rivers-060 -NC_063383.1 RefSeq CDS 57645 58583 . - 0 ID=cds-YP_010377059.1;Parent=gene-NBT03_gp056;Dbxref=Genbank:YP_010377059.1,GeneID:72551472;Name=YP_010377059.1;Note=I1L%3B similar to Vaccinia virus strain Copenhagen I1L%3B virosomal protein essential for virus multiplication;gbkey=CDS;gene_name=OPG077;locus_tag=NBT03_gp056;product=MPXVgp062;protein_id=YP_010377059.1 -NC_063383.1 RefSeq gene 58590 58811 . - . ID=gene-NBT03_gp057;Dbxref=GeneID:72551473;Name=OPG078;gbkey=Gene;gene_name=OPG078;gene_biotype=protein_coding;locus_tag=NBT03_gp057;old_locus_tag=MPXV-M5312_HM12_Rivers-061 -NC_063383.1 RefSeq CDS 58590 58811 . - 0 ID=cds-YP_010377060.1;Parent=gene-NBT03_gp057;Dbxref=Genbank:YP_010377060.1,GeneID:72551473;Name=YP_010377060.1;Note=I2L%3B similar to Vaccinia virus strain Copenhagen I2L;gbkey=CDS;gene_name=OPG078;locus_tag=NBT03_gp057;product=MPXVgp063;protein_id=YP_010377060.1 -NC_063383.1 RefSeq gene 58812 59621 . - . ID=gene-NBT03_gp058;Dbxref=GeneID:72551474;Name=OPG079;gbkey=Gene;gene_name=OPG079;gene_biotype=protein_coding;locus_tag=NBT03_gp058;old_locus_tag=MPXV-M5312_HM12_Rivers-062 -NC_063383.1 RefSeq CDS 58812 59621 . - 0 ID=cds-YP_010377061.1;Parent=gene-NBT03_gp058;Dbxref=Genbank:YP_010377061.1,GeneID:72551474;Name=YP_010377061.1;Note=I3L%3B similar to Vaccinia virus strain Copenhagen I3L%3B virosomal ssDNA-binding phosphoprotein%3B interacts with R2 subunit of ribonucleotide reductase;gbkey=CDS;gene_name=OPG079;locus_tag=NBT03_gp058;product=MPXVgp064;protein_id=YP_010377061.1 -NC_063383.1 RefSeq gene 59703 62018 . - . ID=gene-NBT03_gp059;Dbxref=GeneID:72551475;Name=OPG080;gbkey=Gene;gene_name=OPG080;gene_biotype=protein_coding;locus_tag=NBT03_gp059;old_locus_tag=MPXV-M5312_HM12_Rivers-063 -NC_063383.1 RefSeq CDS 59703 62018 . - 0 ID=cds-YP_010377062.1;Parent=gene-NBT03_gp059;Dbxref=Genbank:YP_010377062.1,GeneID:72551475;Name=YP_010377062.1;Note=I4L%3B similar to Vaccinia virus strain Copenhagen I4L%3B ribonucleotide reductase%2C large subunit%2C R1;gbkey=CDS;gene_name=OPG080;locus_tag=NBT03_gp059;product=MPXVgp065;protein_id=YP_010377062.1 -NC_063383.1 RefSeq gene 62046 62285 . - . ID=gene-NBT03_gp060;Dbxref=GeneID:72551476;Name=OPG081;gbkey=Gene;gene_name=OPG081;gene_biotype=protein_coding;locus_tag=NBT03_gp060;old_locus_tag=MPXV-M5312_HM12_Rivers-064 -NC_063383.1 RefSeq CDS 62046 62285 . - 0 ID=cds-YP_010377063.1;Parent=gene-NBT03_gp060;Dbxref=Genbank:YP_010377063.1,GeneID:72551476;Name=YP_010377063.1;Note=I5L%3B similar to Vaccinia virus strain Copenhagen I5L%3B IMV surface membrane protein;gbkey=CDS;gene_name=OPG081;locus_tag=NBT03_gp060;product=MPXVgp066;protein_id=YP_010377063.1 -NC_063383.1 RefSeq gene 62304 63452 . - . ID=gene-NBT03_gp061;Dbxref=GeneID:72551477;Name=OPG082;gbkey=Gene;gene_name=OPG082;gene_biotype=protein_coding;locus_tag=NBT03_gp061;old_locus_tag=MPXV-M5312_HM12_Rivers-065 -NC_063383.1 RefSeq CDS 62304 63452 . - 0 ID=cds-YP_010377064.1;Parent=gene-NBT03_gp061;Dbxref=Genbank:YP_010377064.1,GeneID:72551477;Name=YP_010377064.1;Note=I6L%3B similar to Vaccinia virus strain Copenhagen I6L;gbkey=CDS;gene_name=OPG082;locus_tag=NBT03_gp061;product=MPXVgp067;protein_id=YP_010377064.1 -NC_063383.1 RefSeq gene 63445 64716 . - . ID=gene-NBT03_gp062;Dbxref=GeneID:72551478;Name=OPG083;gbkey=Gene;gene_name=OPG083;gene_biotype=protein_coding;locus_tag=NBT03_gp062;old_locus_tag=MPXV-M5312_HM12_Rivers-066 -NC_063383.1 RefSeq CDS 63445 64716 . - 0 ID=cds-YP_010377065.1;Parent=gene-NBT03_gp062;Dbxref=Genbank:YP_010377065.1,GeneID:72551478;Name=YP_010377065.1;Note=I7L%3B similar to Vaccinia virus strain Copenhagen I7L%3B virion core protein%3B similar to DNA topoisomerase II;gbkey=CDS;gene_name=OPG083;locus_tag=NBT03_gp062;product=MPXVgp068;protein_id=YP_010377065.1 -NC_063383.1 RefSeq gene 64722 66752 . + . ID=gene-NBT03_gp063;Dbxref=GeneID:72551479;Name=OPG084;gbkey=Gene;gene_name=OPG084;gene_biotype=protein_coding;locus_tag=NBT03_gp063;old_locus_tag=MPXV-M5312_HM12_Rivers-067 -NC_063383.1 RefSeq CDS 64722 66752 . + 0 ID=cds-YP_010377066.1;Parent=gene-NBT03_gp063;Dbxref=Genbank:YP_010377066.1,GeneID:72551479;Name=YP_010377066.1;Note=I8R%3B similar to Vaccinia virus strain Copenhagen I8R%3B nucleoside triphosphate phosphohydrolase II%2C NPH-II%3B DNA and RNA helicase;gbkey=CDS;gene_name=OPG084;locus_tag=NBT03_gp063;product=MPXVgp069;protein_id=YP_010377066.1 -NC_063383.1 RefSeq gene 66756 68531 . - . ID=gene-NBT03_gp064;Dbxref=GeneID:72551480;Name=OPG085;gbkey=Gene;gene_name=OPG085;gene_biotype=protein_coding;locus_tag=NBT03_gp064;old_locus_tag=MPXV-M5312_HM12_Rivers-068 -NC_063383.1 RefSeq CDS 66756 68531 . - 0 ID=cds-YP_010377067.1;Parent=gene-NBT03_gp064;Dbxref=Genbank:YP_010377067.1,GeneID:72551480;Name=YP_010377067.1;Note=G1L%3B similar to Vaccinia virus strain Copenhagen G1L%3B proteinase;gbkey=CDS;gene_name=OPG085;locus_tag=NBT03_gp064;product=MPXVgp070;protein_id=YP_010377067.1 -NC_063383.1 RefSeq gene 68528 68863 . - . ID=gene-NBT03_gp065;Dbxref=GeneID:72551481;Name=OPG086;gbkey=Gene;gene_name=OPG086;gene_biotype=protein_coding;locus_tag=NBT03_gp065;old_locus_tag=MPXV-M5312_HM12_Rivers-069 -NC_063383.1 RefSeq CDS 68528 68863 . - 0 ID=cds-YP_010377068.1;Parent=gene-NBT03_gp065;Dbxref=Genbank:YP_010377068.1,GeneID:72551481;Name=YP_010377068.1;Note=G2L%3B similar to Vaccinia virus strain Copenhagen G3L;gbkey=CDS;gene_name=OPG086;locus_tag=NBT03_gp065;product=MPXVgp071;protein_id=YP_010377068.1 -NC_063383.1 RefSeq gene 68857 69519 . + . ID=gene-NBT03_gp066;Dbxref=GeneID:72551482;Name=OPG087;gbkey=Gene;gene_name=OPG087;gene_biotype=protein_coding;locus_tag=NBT03_gp066;old_locus_tag=MPXV-M5312_HM12_Rivers-070 -NC_063383.1 RefSeq CDS 68857 69519 . + 0 ID=cds-YP_010377069.1;Parent=gene-NBT03_gp066;Dbxref=Genbank:YP_010377069.1,GeneID:72551482;Name=YP_010377069.1;Note=G3R%3B similar to Vaccinia virus strain Copenhagen G2R;gbkey=CDS;gene_name=OPG087;locus_tag=NBT03_gp066;product=MPXVgp072;protein_id=YP_010377069.1 -NC_063383.1 RefSeq gene 69489 69863 . - . ID=gene-NBT03_gp067;Dbxref=GeneID:72551483;Name=OPG088;gbkey=Gene;gene_name=OPG088;gene_biotype=protein_coding;locus_tag=NBT03_gp067;old_locus_tag=MPXV-M5312_HM12_Rivers-071 -NC_063383.1 RefSeq CDS 69489 69863 . - 0 ID=cds-YP_010377070.1;Parent=gene-NBT03_gp067;Dbxref=Genbank:YP_010377070.1,GeneID:72551483;Name=YP_010377070.1;Note=G4L%3B similar to Vaccinia virus strain Copenhagen G4L%3B virion-associated glutaredoxin;gbkey=CDS;gene_name=OPG088;locus_tag=NBT03_gp067;product=MPXVgp073;protein_id=YP_010377070.1 -NC_063383.1 RefSeq gene 69866 71170 . + . ID=gene-NBT03_gp068;Dbxref=GeneID:72551484;Name=OPG089;gbkey=Gene;gene_name=OPG089;gene_biotype=protein_coding;locus_tag=NBT03_gp068;old_locus_tag=MPXV-M5312_HM12_Rivers-072 -NC_063383.1 RefSeq CDS 69866 71170 . + 0 ID=cds-YP_010377071.1;Parent=gene-NBT03_gp068;Dbxref=Genbank:YP_010377071.1,GeneID:72551484;Name=YP_010377071.1;Note=G5R%3B similar to Vaccinia virus strain Copenhagen G5R;gbkey=CDS;gene_name=OPG089;locus_tag=NBT03_gp068;product=MPXVgp074;protein_id=YP_010377071.1 -NC_063383.1 RefSeq gene 71179 71370 . + . ID=gene-NBT03_gp069;Dbxref=GeneID:72551485;Name=OPG090;gbkey=Gene;gene_name=OPG090;gene_biotype=protein_coding;locus_tag=NBT03_gp069;old_locus_tag=MPXV-M5312_HM12_Rivers-073 -NC_063383.1 RefSeq CDS 71179 71370 . + 0 ID=cds-YP_010377072.1;Parent=gene-NBT03_gp069;Dbxref=Genbank:YP_010377072.1,GeneID:72551485;Name=YP_010377072.1;Note=G6R%3B RNA polymerase%2C 7 kDa subunit;gbkey=CDS;gene_name=OPG090;locus_tag=NBT03_gp069;product=MPXVgp075;protein_id=YP_010377072.1 -NC_063383.1 RefSeq gene 71370 71867 . + . ID=gene-NBT03_gp070;Dbxref=GeneID:72551486;Name=OPG091;gbkey=Gene;gene_name=OPG091;gene_biotype=protein_coding;locus_tag=NBT03_gp070;old_locus_tag=MPXV-M5312_HM12_Rivers-074 -NC_063383.1 RefSeq CDS 71370 71867 . + 0 ID=cds-YP_010377073.1;Parent=gene-NBT03_gp070;Dbxref=Genbank:YP_010377073.1,GeneID:72551486;Name=YP_010377073.1;Note=G7R%3B similar to Vaccinia virus strain Copenhagen G6R;gbkey=CDS;gene_name=OPG091;locus_tag=NBT03_gp070;product=MPXVgp076;protein_id=YP_010377073.1 -NC_063383.1 RefSeq gene 71832 72947 . - . ID=gene-NBT03_gp071;Dbxref=GeneID:72551487;Name=OPG092;gbkey=Gene;gene_name=OPG092;gene_biotype=protein_coding;locus_tag=NBT03_gp071;old_locus_tag=MPXV-M5312_HM12_Rivers-075 -NC_063383.1 RefSeq CDS 71832 72947 . - 0 ID=cds-YP_010377074.1;Parent=gene-NBT03_gp071;Dbxref=Genbank:YP_010377074.1,GeneID:72551487;Name=YP_010377074.1;Note=G8L%3B similar to Vaccinia virus strain Copenhagen G7L%3B virion protein;gbkey=CDS;gene_name=OPG092;locus_tag=NBT03_gp071;product=MPXVgp077;protein_id=YP_010377074.1 -NC_063383.1 RefSeq gene 72978 73760 . + . ID=gene-NBT03_gp072;Dbxref=GeneID:72551488;Name=OPG093;gbkey=Gene;gene_name=OPG093;gene_biotype=protein_coding;locus_tag=NBT03_gp072;old_locus_tag=MPXV-M5312_HM12_Rivers-076 -NC_063383.1 RefSeq CDS 72978 73760 . + 0 ID=cds-YP_010377075.1;Parent=gene-NBT03_gp072;Dbxref=Genbank:YP_010377075.1,GeneID:72551488;Name=YP_010377075.1;Note=G9R%3B similar to Vaccinia virus strain Copenhagen G8R%3B late gene transcription factor%2C VLTF-1;gbkey=CDS;gene_name=OPG093;locus_tag=NBT03_gp072;product=MPXVgp078;protein_id=YP_010377075.1 -NC_063383.1 RefSeq gene 73780 74802 . + . ID=gene-NBT03_gp073;Dbxref=GeneID:72551489;Name=OPG094;gbkey=Gene;gene_name=OPG094;gene_biotype=protein_coding;locus_tag=NBT03_gp073;old_locus_tag=MPXV-M5312_HM12_Rivers-077 -NC_063383.1 RefSeq CDS 73780 74802 . + 0 ID=cds-YP_010377076.1;Parent=gene-NBT03_gp073;Dbxref=Genbank:YP_010377076.1,GeneID:72551489;Name=YP_010377076.1;Note=G10R%3B similar to Vaccinia virus strain Copenhagen G9R%3B myristylated protein;gbkey=CDS;gene_name=OPG094;locus_tag=NBT03_gp073;product=MPXVgp079;protein_id=YP_010377076.1 -NC_063383.1 RefSeq gene 74803 75555 . + . ID=gene-NBT03_gp074;Dbxref=GeneID:72551490;Name=OPG095;gbkey=Gene;gene_name=OPG095;gene_biotype=protein_coding;locus_tag=NBT03_gp074;old_locus_tag=MPXV-M5312_HM12_Rivers-078 -NC_063383.1 RefSeq CDS 74803 75555 . + 0 ID=cds-YP_010377077.1;Parent=gene-NBT03_gp074;Dbxref=Genbank:YP_010377077.1,GeneID:72551490;Name=YP_010377077.1;Note=M1R%3B similar to Vaccinia virus strain Copenhagen L1R%3B myristylated IMV surface membrane protein;gbkey=CDS;gene_name=OPG095;locus_tag=NBT03_gp074;product=MPXVgp080;protein_id=YP_010377077.1 -NC_063383.1 RefSeq gene 75587 75865 . + . ID=gene-NBT03_gp075;Dbxref=GeneID:72551491;Name=OPG096;gbkey=Gene;gene_name=OPG096;gene_biotype=protein_coding;locus_tag=NBT03_gp075;old_locus_tag=MPXV-M5312_HM12_Rivers-079 -NC_063383.1 RefSeq CDS 75587 75865 . + 0 ID=cds-YP_010377078.1;Parent=gene-NBT03_gp075;Dbxref=Genbank:YP_010377078.1,GeneID:72551491;Name=YP_010377078.1;Note=M2R%3B similar to Vaccinia virus strain Copenhagen L2R;gbkey=CDS;gene_name=OPG096;locus_tag=NBT03_gp075;product=MPXVgp081;protein_id=YP_010377078.1 -NC_063383.1 RefSeq gene 75841 76875 . - . ID=gene-NBT03_gp076;Dbxref=GeneID:72551492;Name=OPG097;gbkey=Gene;gene_name=OPG097;gene_biotype=protein_coding;locus_tag=NBT03_gp076;old_locus_tag=MPXV-M5312_HM12_Rivers-080 -NC_063383.1 RefSeq CDS 75841 76875 . - 0 ID=cds-YP_010377079.1;Parent=gene-NBT03_gp076;Dbxref=Genbank:YP_010377079.1,GeneID:72551492;Name=YP_010377079.1;Note=M3L%3B similar to Vaccinia virus strain Copenhagen L3L;gbkey=CDS;gene_name=OPG097;locus_tag=NBT03_gp076;product=MPXVgp082;protein_id=YP_010377079.1 -NC_063383.1 RefSeq gene 76900 77655 . + . ID=gene-NBT03_gp077;Dbxref=GeneID:72551493;Name=OPG098;gbkey=Gene;gene_name=OPG098;gene_biotype=protein_coding;locus_tag=NBT03_gp077;old_locus_tag=MPXV-M5312_HM12_Rivers-081 -NC_063383.1 RefSeq CDS 76900 77655 . + 0 ID=cds-YP_010377080.1;Parent=gene-NBT03_gp077;Dbxref=Genbank:YP_010377080.1,GeneID:72551493;Name=YP_010377080.1;Note=M4R%3B similar to Vaccinia virus strain Copenhagen L4R%3B virion core protein%3B ssDNA binding%3B stimulation of I8R helicase activity;gbkey=CDS;gene_name=OPG098;locus_tag=NBT03_gp077;product=MPXVgp083;protein_id=YP_010377080.1 -NC_063383.1 RefSeq gene 77665 78051 . + . ID=gene-NBT03_gp078;Dbxref=GeneID:72551494;Name=OPG099;gbkey=Gene;gene_name=OPG099;gene_biotype=protein_coding;locus_tag=NBT03_gp078;old_locus_tag=MPXV-M5312_HM12_Rivers-082 -NC_063383.1 RefSeq CDS 77665 78051 . + 0 ID=cds-YP_010377081.1;Parent=gene-NBT03_gp078;Dbxref=Genbank:YP_010377081.1,GeneID:72551494;Name=YP_010377081.1;Note=M5R%3B similar to Vaccinia virus strain Copenhagen L5R;gbkey=CDS;gene_name=OPG099;locus_tag=NBT03_gp078;product=MPXVgp084;protein_id=YP_010377081.1 -NC_063383.1 RefSeq gene 78008 78466 . + . ID=gene-NBT03_gp079;Dbxref=GeneID:72551495;Name=OPG100;gbkey=Gene;gene_name=OPG100;gene_biotype=protein_coding;locus_tag=NBT03_gp079;old_locus_tag=MPXV-M5312_HM12_Rivers-083 -NC_063383.1 RefSeq CDS 78008 78466 . + 0 ID=cds-YP_010377082.1;Parent=gene-NBT03_gp079;Dbxref=Genbank:YP_010377082.1,GeneID:72551495;Name=YP_010377082.1;Note=L1R%3B similar to Vaccinia virus strain Copenhagen J1R;gbkey=CDS;gene_name=OPG100;locus_tag=NBT03_gp079;product=MPXVgp085;protein_id=YP_010377082.1 -NC_063383.1 RefSeq gene 78486 79019 . + . ID=gene-NBT03_gp080;Dbxref=GeneID:72551496;Name=OPG101;gbkey=Gene;gene_name=OPG101;gene_biotype=protein_coding;locus_tag=NBT03_gp080;old_locus_tag=MPXV-M5312_HM12_Rivers-084 -NC_063383.1 RefSeq CDS 78486 79019 . + 0 ID=cds-YP_010377083.1;Parent=gene-NBT03_gp080;Dbxref=Genbank:YP_010377083.1,GeneID:72551496;Name=YP_010377083.1;Note=L2R%3B similar to Vaccinia virus strain Copenhagen J2R%3B thymidine kinase;gbkey=CDS;gene_name=OPG101;locus_tag=NBT03_gp080;product=MPXVgp086;protein_id=YP_010377083.1 -NC_063383.1 RefSeq gene 79085 80086 . + . ID=gene-NBT03_gp081;Dbxref=GeneID:72551497;Name=OPG102;gbkey=Gene;gene_name=OPG102;gene_biotype=protein_coding;locus_tag=NBT03_gp081;old_locus_tag=MPXV-M5312_HM12_Rivers-085 -NC_063383.1 RefSeq CDS 79085 80086 . + 0 ID=cds-YP_010377084.1;Parent=gene-NBT03_gp081;Dbxref=Genbank:YP_010377084.1,GeneID:72551497;Name=YP_010377084.1;Note=L3R%3B similar to Vaccinia virus strain Copenhagen J3R%3B poly-A polymerase%2C stimulatory subunit%2C simultaneously cap-specific mRNA (nucleoside-O2'-)-methyltransferase;gbkey=CDS;gene_name=OPG102;locus_tag=NBT03_gp081;product=MPXVgp087;protein_id=YP_010377084.1 -NC_063383.1 RefSeq gene 80001 80558 . + . ID=gene-NBT03_gp082;Dbxref=GeneID:72551498;Name=OPG103;gbkey=Gene;gene_name=OPG103;gene_biotype=protein_coding;locus_tag=NBT03_gp082;old_locus_tag=MPXV-M5312_HM12_Rivers-086 -NC_063383.1 RefSeq CDS 80001 80558 . + 0 ID=cds-YP_010377085.1;Parent=gene-NBT03_gp082;Dbxref=Genbank:YP_010377085.1,GeneID:72551498;Name=YP_010377085.1;Note=L4R%3B similar to Vaccinia virus strain Copenhagen J4R%3B RNA polymerase%2C 22 kDa subunit;gbkey=CDS;gene_name=OPG103;locus_tag=NBT03_gp082;product=MPXVgp088;protein_id=YP_010377085.1 -NC_063383.1 RefSeq gene 80618 81019 . - . ID=gene-NBT03_gp083;Dbxref=GeneID:72551499;Name=OPG104;gbkey=Gene;gene_name=OPG104;gene_biotype=protein_coding;locus_tag=NBT03_gp083;old_locus_tag=MPXV-M5312_HM12_Rivers-087 -NC_063383.1 RefSeq CDS 80618 81019 . - 0 ID=cds-YP_010377086.1;Parent=gene-NBT03_gp083;Dbxref=Genbank:YP_010377086.1,GeneID:72551499;Name=YP_010377086.1;Note=L5L%3B similar to Vaccinia virus strain Copenhagen J5L%3B essential for virus multiplication;gbkey=CDS;gene_name=OPG104;locus_tag=NBT03_gp083;product=MPXVgp089;protein_id=YP_010377086.1 -NC_063383.1 RefSeq gene 81126 84986 . + . ID=gene-NBT03_gp084;Dbxref=GeneID:72551500;Name=OPG105;gbkey=Gene;gene_name=OPG105;gene_biotype=protein_coding;locus_tag=NBT03_gp084;old_locus_tag=MPXV-M5312_HM12_Rivers-088 -NC_063383.1 RefSeq CDS 81126 84986 . + 0 ID=cds-YP_010377087.1;Parent=gene-NBT03_gp084;Dbxref=Genbank:YP_010377087.1,GeneID:72551500;Name=YP_010377087.1;Note=L6R%3B similar to Vaccinia virus strain Copenhagen J6R%3B RNA polymerase%2C 147 kDa subunit;gbkey=CDS;gene_name=OPG105;locus_tag=NBT03_gp084;product=MPXVgp090;protein_id=YP_010377087.1 -NC_063383.1 RefSeq gene 84983 85498 . - . ID=gene-NBT03_gp085;Dbxref=GeneID:72551501;Name=OPG106;gbkey=Gene;gene_name=OPG106;gene_biotype=protein_coding;locus_tag=NBT03_gp085;old_locus_tag=MPXV-M5312_HM12_Rivers-089 -NC_063383.1 RefSeq CDS 84983 85498 . - 0 ID=cds-YP_010377088.1;Parent=gene-NBT03_gp085;Dbxref=Genbank:YP_010377088.1,GeneID:72551501;Name=YP_010377088.1;Note=H1L%3B similar to Vaccinia virus strain Copenhagen H1L%3B tyrosine;gbkey=CDS;gene_name=OPG106;locus_tag=NBT03_gp085;product=MPXVgp091;protein_id=YP_010377088.1 -NC_063383.1 RefSeq gene 85512 86081 . + . ID=gene-NBT03_gp086;Dbxref=GeneID:72551502;Name=OPG107;gbkey=Gene;gene_name=OPG107;gene_biotype=protein_coding;locus_tag=NBT03_gp086;old_locus_tag=MPXV-M5312_HM12_Rivers-090 -NC_063383.1 RefSeq CDS 85512 86081 . + 0 ID=cds-YP_010377089.1;Parent=gene-NBT03_gp086;Dbxref=Genbank:YP_010377089.1,GeneID:72551502;Name=YP_010377089.1;Note=H2R%3B similar to Vaccinia virus strain Copenhagen H2R;gbkey=CDS;gene_name=OPG107;locus_tag=NBT03_gp086;product=MPXVgp092;protein_id=YP_010377089.1 -NC_063383.1 RefSeq gene 86085 87059 . - . ID=gene-NBT03_gp087;Dbxref=GeneID:72551503;Name=OPG108;gbkey=Gene;gene_name=OPG108;gene_biotype=protein_coding;locus_tag=NBT03_gp087;old_locus_tag=MPXV-M5312_HM12_Rivers-091 -NC_063383.1 RefSeq CDS 86085 87059 . - 0 ID=cds-YP_010377090.1;Parent=gene-NBT03_gp087;Dbxref=Genbank:YP_010377090.1,GeneID:72551503;Name=YP_010377090.1;Note=H3L%3B similar to Vaccinia virus strain Copenhagen H3L%3B IMV surface membrane protein;gbkey=CDS;gene_name=OPG108;locus_tag=NBT03_gp087;product=MPXVgp093;protein_id=YP_010377090.1 -NC_063383.1 RefSeq gene 87060 89447 . - . ID=gene-NBT03_gp088;Dbxref=GeneID:72551504;Name=OPG109;gbkey=Gene;gene_name=OPG109;gene_biotype=protein_coding;locus_tag=NBT03_gp088;old_locus_tag=MPXV-M5312_HM12_Rivers-092 -NC_063383.1 RefSeq CDS 87060 89447 . - 0 ID=cds-YP_010377091.1;Parent=gene-NBT03_gp088;Dbxref=Genbank:YP_010377091.1,GeneID:72551504;Name=YP_010377091.1;Note=H4L%3B similar to Vaccinia virus strain Copenhagen H4L%3B virion core RNA polymerase-associated protein%2C RAP94;gbkey=CDS;gene_name=OPG109;locus_tag=NBT03_gp088;product=MPXVgp094;protein_id=YP_010377091.1 -NC_063383.1 RefSeq gene 89632 90264 . + . ID=gene-NBT03_gp089;Dbxref=GeneID:72551505;Name=OPG110;gbkey=Gene;gene_name=OPG110;gene_biotype=protein_coding;locus_tag=NBT03_gp089;old_locus_tag=MPXV-M5312_HM12_Rivers-093 -NC_063383.1 RefSeq CDS 89632 90264 . + 0 ID=cds-YP_010377092.1;Parent=gene-NBT03_gp089;Dbxref=Genbank:YP_010377092.1,GeneID:72551505;Name=YP_010377092.1;Note=H5R%3B similar to Vaccinia virus strain Copenhagen H5R%3B virosome-associated late gene transcription factor%2C VLTF-4%3B Ca2+-binding motif;gbkey=CDS;gene_name=OPG110;locus_tag=NBT03_gp089;product=MPXVgp095;protein_id=YP_010377092.1 -NC_063383.1 RefSeq gene 90265 91209 . + . ID=gene-NBT03_gp090;Dbxref=GeneID:72551506;Name=OPG111;gbkey=Gene;gene_name=OPG111;gene_biotype=protein_coding;locus_tag=NBT03_gp090;old_locus_tag=MPXV-M5312_HM12_Rivers-094 -NC_063383.1 RefSeq CDS 90265 91209 . + 0 ID=cds-YP_010377093.1;Parent=gene-NBT03_gp090;Dbxref=Genbank:YP_010377093.1,GeneID:72551506;Name=YP_010377093.1;Note=H6R%3B similar to Vaccinia virus strain Copenhagen H6R%3B DNA topoisomerase;gbkey=CDS;gene_name=OPG111;locus_tag=NBT03_gp090;product=MPXVgp096;protein_id=YP_010377093.1 -NC_063383.1 RefSeq gene 91247 91687 . + . ID=gene-NBT03_gp091;Dbxref=GeneID:72551507;Name=OPG112;gbkey=Gene;gene_name=OPG112;gene_biotype=protein_coding;locus_tag=NBT03_gp091;old_locus_tag=MPXV-M5312_HM12_Rivers-095 -NC_063383.1 RefSeq CDS 91247 91687 . + 0 ID=cds-YP_010377094.1;Parent=gene-NBT03_gp091;Dbxref=Genbank:YP_010377094.1,GeneID:72551507;Name=YP_010377094.1;Note=H7R%3B similar to Vaccinia virus strain Copenhagen H7R;gbkey=CDS;gene_name=OPG112;locus_tag=NBT03_gp091;product=MPXVgp097;protein_id=YP_010377094.1 -NC_063383.1 RefSeq gene 91731 94268 . + . ID=gene-NBT03_gp092;Dbxref=GeneID:72551508;Name=OPG113;gbkey=Gene;gene_name=OPG113;gene_biotype=protein_coding;locus_tag=NBT03_gp092;old_locus_tag=MPXV-M5312_HM12_Rivers-096 -NC_063383.1 RefSeq CDS 91731 94268 . + 0 ID=cds-YP_010377095.1;Parent=gene-NBT03_gp092;Dbxref=Genbank:YP_010377095.1,GeneID:72551508;Name=YP_010377095.1;Note=E1R%3B similar to Vaccinia virus strain Copenhagen D1R%3B mRNA capping enzyme%2C large subunit%3B RNA 5' triphosphatase and RNA guanylyl transferase activities;gbkey=CDS;gene_name=OPG113;locus_tag=NBT03_gp092;product=MPXVgp098;protein_id=YP_010377095.1 -NC_063383.1 RefSeq gene 94227 94667 . - . ID=gene-NBT03_gp093;Dbxref=GeneID:72551509;Name=OPG114;gbkey=Gene;gene_name=OPG114;gene_biotype=protein_coding;locus_tag=NBT03_gp093;old_locus_tag=MPXV-M5312_HM12_Rivers-097 -NC_063383.1 RefSeq CDS 94227 94667 . - 0 ID=cds-YP_010377096.1;Parent=gene-NBT03_gp093;Dbxref=Genbank:YP_010377096.1,GeneID:72551509;Name=YP_010377096.1;Note=E2L%3B similar to Vaccinia virus strain Copenhagen D2L%3B virion core protein;gbkey=CDS;gene_name=OPG114;locus_tag=NBT03_gp093;product=MPXVgp099;protein_id=YP_010377096.1 -NC_063383.1 RefSeq gene 94660 95361 . + . ID=gene-NBT03_gp094;Dbxref=GeneID:72551510;Name=OPG115;gbkey=Gene;gene_name=OPG115;gene_biotype=protein_coding;locus_tag=NBT03_gp094;old_locus_tag=MPXV-M5312_HM12_Rivers-098 -NC_063383.1 RefSeq CDS 94660 95361 . + 0 ID=cds-YP_010377097.1;Parent=gene-NBT03_gp094;Dbxref=Genbank:YP_010377097.1,GeneID:72551510;Name=YP_010377097.1;Note=E3R%3B similar to Vaccinia virus strain Copenhagen D3R%3B virion core protein;gbkey=CDS;gene_name=OPG115;locus_tag=NBT03_gp094;product=MPXVgp100;protein_id=YP_010377097.1 -NC_063383.1 RefSeq gene 95361 96017 . + . ID=gene-NBT03_gp095;Dbxref=GeneID:72551511;Name=OPG116;gbkey=Gene;gene_name=OPG116;gene_biotype=protein_coding;locus_tag=NBT03_gp095;old_locus_tag=MPXV-M5312_HM12_Rivers-099 -NC_063383.1 RefSeq CDS 95361 96017 . + 0 ID=cds-YP_010377098.1;Parent=gene-NBT03_gp095;Dbxref=Genbank:YP_010377098.1,GeneID:72551511;Name=YP_010377098.1;Note=E4R%3B similar to Vaccinia virus strain Copenhagen D4R%3B uracil DNA glycosylase;gbkey=CDS;gene_name=OPG116;locus_tag=NBT03_gp095;product=MPXVgp101;protein_id=YP_010377098.1 -NC_063383.1 RefSeq gene 96049 98406 . + . ID=gene-NBT03_gp096;Dbxref=GeneID:72551512;Name=OPG117;gbkey=Gene;gene_name=OPG117;gene_biotype=protein_coding;locus_tag=NBT03_gp096;old_locus_tag=MPXV-M5312_HM12_Rivers-100 -NC_063383.1 RefSeq CDS 96049 98406 . + 0 ID=cds-YP_010377099.1;Parent=gene-NBT03_gp096;Dbxref=Genbank:YP_010377099.1,GeneID:72551512;Name=YP_010377099.1;Note=E5R%3B similar to Vaccinia virus strain Copenhagen D5R%3B nucleic acid-independent nucleoside triphosphatase;gbkey=CDS;gene_name=OPG117;locus_tag=NBT03_gp096;product=MPXVgp102;protein_id=YP_010377099.1 -NC_063383.1 RefSeq gene 98446 100359 . + . ID=gene-NBT03_gp097;Dbxref=GeneID:72551513;Name=OPG118;gbkey=Gene;gene_name=OPG118;gene_biotype=protein_coding;locus_tag=NBT03_gp097;old_locus_tag=MPXV-M5312_HM12_Rivers-101 -NC_063383.1 RefSeq CDS 98446 100359 . + 0 ID=cds-YP_010377100.1;Parent=gene-NBT03_gp097;Dbxref=Genbank:YP_010377100.1,GeneID:72551513;Name=YP_010377100.1;Note=E6R%3B similar to Vaccinia virus strain Copenhagen D6R%3B early transcription factor%2C VETF%2C small subunit;gbkey=CDS;gene_name=OPG118;locus_tag=NBT03_gp097;product=MPXVgp103;protein_id=YP_010377100.1 -NC_063383.1 RefSeq gene 100386 100871 . + . ID=gene-NBT03_gp098;Dbxref=GeneID:72551514;Name=OPG119;gbkey=Gene;gene_name=OPG119;gene_biotype=protein_coding;locus_tag=NBT03_gp098;old_locus_tag=MPXV-M5312_HM12_Rivers-102 -NC_063383.1 RefSeq CDS 100386 100871 . + 0 ID=cds-YP_010377101.1;Parent=gene-NBT03_gp098;Dbxref=Genbank:YP_010377101.1,GeneID:72551514;Name=YP_010377101.1;Note=E7R%3B similar to Vaccinia virus strain Copenhagen D7R%3B RNA polymerase%2C 18 kDa subunit;gbkey=CDS;gene_name=OPG119;locus_tag=NBT03_gp098;product=MPXVgp104;protein_id=YP_010377101.1 -NC_063383.1 RefSeq gene 100834 101748 . - . ID=gene-NBT03_gp099;Dbxref=GeneID:72551515;Name=OPG120;gbkey=Gene;gene_name=OPG120;gene_biotype=protein_coding;locus_tag=NBT03_gp099;old_locus_tag=MPXV-M5312_HM12_Rivers-103 -NC_063383.1 RefSeq CDS 100834 101748 . - 0 ID=cds-YP_010377102.1;Parent=gene-NBT03_gp099;Dbxref=Genbank:YP_010377102.1,GeneID:72551515;Name=YP_010377102.1;Note=E8L%3B similar to Vaccinia virus strain Copenhagen D8L%3B IMV surface membrane 32 kDa protein%3B binding to cell surface chondroitin sulfate%3B IMV adsorption to cell surface;gbkey=CDS;gene_name=OPG120;locus_tag=NBT03_gp099;product=MPXVgp105;protein_id=YP_010377102.1 -NC_063383.1 RefSeq gene 101790 102431 . + . ID=gene-NBT03_gp100;Dbxref=GeneID:72551516;Name=OPG121;gbkey=Gene;gene_name=OPG121;gene_biotype=protein_coding;locus_tag=NBT03_gp100;old_locus_tag=MPXV-M5312_HM12_Rivers-104 -NC_063383.1 RefSeq CDS 101790 102431 . + 0 ID=cds-YP_010377103.1;Parent=gene-NBT03_gp100;Dbxref=Genbank:YP_010377103.1,GeneID:72551516;Name=YP_010377103.1;Note=E9R%3B similar to Vaccinia virus strain Copenhagen D9R%3B Mut-like;gbkey=CDS;gene_name=OPG121;locus_tag=NBT03_gp100;product=MPXVgp106;protein_id=YP_010377103.1 -NC_063383.1 RefSeq gene 102428 103174 . + . ID=gene-NBT03_gp101;Dbxref=GeneID:72551517;Name=OPG122;gbkey=Gene;gene_name=OPG122;gene_biotype=protein_coding;locus_tag=NBT03_gp101;old_locus_tag=MPXV-M5312_HM12_Rivers-105 -NC_063383.1 RefSeq CDS 102428 103174 . + 0 ID=cds-YP_010377104.1;Parent=gene-NBT03_gp101;Dbxref=Genbank:YP_010377104.1,GeneID:72551517;Name=YP_010377104.1;Note=E10R%3B similar to Vaccinia virus strain Copenhagen D10R%3B down regulation of gene expression%3B Mut-like;gbkey=CDS;gene_name=OPG122;locus_tag=NBT03_gp101;product=MPXVgp107;protein_id=YP_010377104.1 -NC_063383.1 RefSeq gene 103175 105070 . - . ID=gene-NBT03_gp102;Dbxref=GeneID:72551518;Name=OPG123;gbkey=Gene;gene_name=OPG123;gene_biotype=protein_coding;locus_tag=NBT03_gp102;old_locus_tag=MPXV-M5312_HM12_Rivers-106 -NC_063383.1 RefSeq CDS 103175 105070 . - 0 ID=cds-YP_010377105.1;Parent=gene-NBT03_gp102;Dbxref=Genbank:YP_010377105.1,GeneID:72551518;Name=YP_010377105.1;Note=E11L%3B similar to Vaccinia virus strain Copenhagen D11L%3B nucleoside triphosphate phosphohydrolase I%2C NPH I%3B DNA-dependent ATPase%3B early gene transcription termination factor;gbkey=CDS;gene_name=OPG123;locus_tag=NBT03_gp102;product=MPXVgp108;protein_id=YP_010377105.1 -NC_063383.1 RefSeq gene 105105 105968 . - . ID=gene-NBT03_gp103;Dbxref=GeneID:72551519;Name=OPG124;gbkey=Gene;gene_name=OPG124;gene_biotype=protein_coding;locus_tag=NBT03_gp103;old_locus_tag=MPXV-M5312_HM12_Rivers-107 -NC_063383.1 RefSeq CDS 105105 105968 . - 0 ID=cds-YP_010377106.1;Parent=gene-NBT03_gp103;Dbxref=Genbank:YP_010377106.1,GeneID:72551519;Name=YP_010377106.1;Note=E12L%3B similar to Vaccinia virus strain Copenhagen D12L%3B mRNA capping enzyme%2C small subunit%3B mRNA (guanine-N7-)-methyl-transferase%3B transcription initiation factor;gbkey=CDS;gene_name=OPG124;locus_tag=NBT03_gp103;product=MPXVgp109;protein_id=YP_010377106.1 -NC_063383.1 RefSeq gene 105999 107654 . - . ID=gene-NBT03_gp104;Dbxref=GeneID:72551520;Name=OPG125;gbkey=Gene;gene_name=OPG125;gene_biotype=protein_coding;locus_tag=NBT03_gp104;old_locus_tag=MPXV-M5312_HM12_Rivers-108 -NC_063383.1 RefSeq CDS 105999 107654 . - 0 ID=cds-YP_010377107.1;Parent=gene-NBT03_gp104;Dbxref=Genbank:YP_010377107.1,GeneID:72551520;Name=YP_010377107.1;Note=E13L%3B similar to Vaccinia virus strain Copenhagen D13L%3B protein needed for the formation of immature IMV surface membrane;gbkey=CDS;gene_name=OPG125;locus_tag=NBT03_gp104;product=MPXVgp110;protein_id=YP_010377107.1 -NC_063383.1 RefSeq gene 107678 108130 . - . ID=gene-NBT03_gp105;Dbxref=GeneID:72551521;Name=OPG126;gbkey=Gene;gene_name=OPG126;gene_biotype=protein_coding;locus_tag=NBT03_gp105;old_locus_tag=MPXV-M5312_HM12_Rivers-109 -NC_063383.1 RefSeq CDS 107678 108130 . - 0 ID=cds-YP_010377108.1;Parent=gene-NBT03_gp105;Dbxref=Genbank:YP_010377108.1,GeneID:72551521;Name=YP_010377108.1;Note=A1L%3B similar to Vaccinia virus strain Copenhagen A1L%3B late gene transcription factor%2C VLTF-2;gbkey=CDS;gene_name=OPG126;locus_tag=NBT03_gp105;product=MPXVgp111;protein_id=YP_010377108.1 -NC_063383.1 RefSeq gene 108151 108825 . - . ID=gene-NBT03_gp106;Dbxref=GeneID:72551522;Name=OPG127;gbkey=Gene;gene_name=OPG127;gene_biotype=protein_coding;locus_tag=NBT03_gp106;old_locus_tag=MPXV-M5312_HM12_Rivers-110 -NC_063383.1 RefSeq CDS 108151 108825 . - 0 ID=cds-YP_010377109.1;Parent=gene-NBT03_gp106;Dbxref=Genbank:YP_010377109.1,GeneID:72551522;Name=YP_010377109.1;Note=A2L%3B similar to Vaccinia virus strain Copenhagen A2L%3B late gene transcription factor%2C VLTF-3%3B zinc binding;gbkey=CDS;gene_name=OPG127;locus_tag=NBT03_gp106;product=MPXVgp112;protein_id=YP_010377109.1 -NC_063383.1 RefSeq gene 108822 109055 . - . ID=gene-NBT03_gp107;Dbxref=GeneID:72551523;Name=OPG128;gbkey=Gene;gene_name=OPG128;gene_biotype=protein_coding;locus_tag=NBT03_gp107;old_locus_tag=MPXV-M5312_HM12_Rivers-111 -NC_063383.1 RefSeq CDS 108822 109055 . - 0 ID=cds-YP_010377110.1;Parent=gene-NBT03_gp107;Dbxref=Genbank:YP_010377110.1,GeneID:72551523;Name=YP_010377110.1;Note=A3L;gbkey=CDS;gene_name=OPG128;locus_tag=NBT03_gp107;product=MPXVgp113;protein_id=YP_010377110.1 -NC_063383.1 RefSeq gene 109070 111004 . - . ID=gene-NBT03_gp108;Dbxref=GeneID:72551524;Name=OPG129;gbkey=Gene;gene_name=OPG129;gene_biotype=protein_coding;locus_tag=NBT03_gp108;old_locus_tag=MPXV-M5312_HM12_Rivers-112 -NC_063383.1 RefSeq CDS 109070 111004 . - 0 ID=cds-YP_010377111.1;Parent=gene-NBT03_gp108;Dbxref=Genbank:YP_010377111.1,GeneID:72551524;Name=YP_010377111.1;Note=A4L%3B similar to Vaccinia virus strain Copenhagen A3L%3B major virion core protein p4b;gbkey=CDS;gene_name=OPG129;locus_tag=NBT03_gp108;product=MPXVgp114;protein_id=YP_010377111.1 -NC_063383.1 RefSeq gene 111057 111902 . - . ID=gene-NBT03_gp109;Dbxref=GeneID:72551525;Name=OPG130;gbkey=Gene;gene_name=OPG130;gene_biotype=protein_coding;locus_tag=NBT03_gp109;old_locus_tag=MPXV-M5312_HM12_Rivers-113 -NC_063383.1 RefSeq CDS 111057 111902 . - 0 ID=cds-YP_010377112.1;Parent=gene-NBT03_gp109;Dbxref=Genbank:YP_010377112.1,GeneID:72551525;Name=YP_010377112.1;Note=A5L%3B similar to Vaccinia virus strain Copenhagen A4L%3B 39 kDa immunodominant virion core protein needed for the progression of IV to infectious IMV;gbkey=CDS;gene_name=OPG130;locus_tag=NBT03_gp109;product=MPXVgp115;protein_id=YP_010377112.1 -NC_063383.1 RefSeq gene 111940 112425 . + . ID=gene-NBT03_gp110;Dbxref=GeneID:72551526;Name=OPG131;gbkey=Gene;gene_name=OPG131;gene_biotype=protein_coding;locus_tag=NBT03_gp110;old_locus_tag=MPXV-M5312_HM12_Rivers-114 -NC_063383.1 RefSeq CDS 111940 112425 . + 0 ID=cds-YP_010377113.1;Parent=gene-NBT03_gp110;Dbxref=Genbank:YP_010377113.1,GeneID:72551526;Name=YP_010377113.1;Note=A6R%3B similar to Vaccinia virus strain Copenhagen A5R%3B precursor of RNA polymerase 22 kDa and 21 kDa;gbkey=CDS;gene_name=OPG131;locus_tag=NBT03_gp110;product=MPXVgp116;protein_id=YP_010377113.1 -NC_063383.1 RefSeq gene 112422 113540 . - . ID=gene-NBT03_gp111;Dbxref=GeneID:72551527;Name=OPG132;gbkey=Gene;gene_name=OPG132;gene_biotype=protein_coding;locus_tag=NBT03_gp111;old_locus_tag=MPXV-M5312_HM12_Rivers-115 -NC_063383.1 RefSeq CDS 112422 113540 . - 0 ID=cds-YP_010377114.1;Parent=gene-NBT03_gp111;Dbxref=Genbank:YP_010377114.1,GeneID:72551527;Name=YP_010377114.1;Note=A7L%3B similar to Vaccinia virus strain Copenhagen A6L;gbkey=CDS;gene_name=OPG132;locus_tag=NBT03_gp111;product=MPXVgp117;protein_id=YP_010377114.1 -NC_063383.1 RefSeq gene 113564 115696 . - . ID=gene-NBT03_gp112;Dbxref=GeneID:72551528;Name=OPG133;gbkey=Gene;gene_name=OPG133;gene_biotype=protein_coding;locus_tag=NBT03_gp112;old_locus_tag=MPXV-M5312_HM12_Rivers-116 -NC_063383.1 RefSeq CDS 113564 115696 . - 0 ID=cds-YP_010377115.1;Parent=gene-NBT03_gp112;Dbxref=Genbank:YP_010377115.1,GeneID:72551528;Name=YP_010377115.1;Note=A8L%3B similar to Vaccinia virus strain Copenhagen A7L%3B early transcription factor%2C VETF%2C large subunit%3B needed for morphogenesis of the virion core;gbkey=CDS;gene_name=OPG133;locus_tag=NBT03_gp112;product=MPXVgp118;protein_id=YP_010377115.1 -NC_063383.1 RefSeq gene 115750 116628 . + . ID=gene-NBT03_gp113;Dbxref=GeneID:72551529;Name=OPG134;gbkey=Gene;gene_name=OPG134;gene_biotype=protein_coding;locus_tag=NBT03_gp113;old_locus_tag=MPXV-M5312_HM12_Rivers-117 -NC_063383.1 RefSeq CDS 115750 116628 . + 0 ID=cds-YP_010377116.1;Parent=gene-NBT03_gp113;Dbxref=Genbank:YP_010377116.1,GeneID:72551529;Name=YP_010377116.1;Note=A9R%3B similar to Vaccinia virus strain Copenhagen A8R%3B intermediate transcription factor%2C VITF-3%2C 34 kDa;gbkey=CDS;gene_name=OPG134;locus_tag=NBT03_gp113;product=MPXVgp119;protein_id=YP_010377116.1 -NC_063383.1 RefSeq gene 116609 116911 . - . ID=gene-NBT03_gp114;Dbxref=GeneID:72551530;Name=OPG135;gbkey=Gene;gene_name=OPG135;gene_biotype=protein_coding;locus_tag=NBT03_gp114;old_locus_tag=MPXV-M5312_HM12_Rivers-118 -NC_063383.1 RefSeq CDS 116609 116911 . - 0 ID=cds-YP_010377117.1;Parent=gene-NBT03_gp114;Dbxref=Genbank:YP_010377117.1,GeneID:72551530;Name=YP_010377117.1;Note=A10L%3B similar to Vaccinia virus strain Copenhagen A9L;gbkey=CDS;gene_name=OPG135;locus_tag=NBT03_gp114;product=MPXVgp120;protein_id=YP_010377117.1 -NC_063383.1 RefSeq gene 116912 119587 . - . ID=gene-NBT03_gp115;Dbxref=GeneID:72551531;Name=OPG136;gbkey=Gene;gene_name=OPG136;gene_biotype=protein_coding;locus_tag=NBT03_gp115;old_locus_tag=MPXV-M5312_HM12_Rivers-119 -NC_063383.1 RefSeq CDS 116912 119587 . - 0 ID=cds-YP_010377118.1;Parent=gene-NBT03_gp115;Dbxref=Genbank:YP_010377118.1,GeneID:72551531;Name=YP_010377118.1;Note=A11L%3B similar to Vaccinia virus strain Copenhagen A10L%3B major virion core protein p4a;gbkey=CDS;gene_name=OPG136;locus_tag=NBT03_gp115;product=MPXVgp121;protein_id=YP_010377118.1 -NC_063383.1 RefSeq gene 119602 120558 . + . ID=gene-NBT03_gp116;Dbxref=GeneID:72551532;Name=OPG137;gbkey=Gene;gene_name=OPG137;gene_biotype=protein_coding;locus_tag=NBT03_gp116;old_locus_tag=MPXV-M5312_HM12_Rivers-120 -NC_063383.1 RefSeq CDS 119602 120558 . + 0 ID=cds-YP_010377119.1;Parent=gene-NBT03_gp116;Dbxref=Genbank:YP_010377119.1,GeneID:72551532;Name=YP_010377119.1;Note=A12R%3B similar to Vaccinia virus strain Copenhagen A11R;gbkey=CDS;gene_name=OPG137;locus_tag=NBT03_gp116;product=MPXVgp122;protein_id=YP_010377119.1 -NC_063383.1 RefSeq gene 120560 121132 . - . ID=gene-NBT03_gp117;Dbxref=GeneID:72551533;Name=OPG138;gbkey=Gene;gene_name=OPG138;gene_biotype=protein_coding;locus_tag=NBT03_gp117;old_locus_tag=MPXV-M5312_HM12_Rivers-121 -NC_063383.1 RefSeq CDS 120560 121132 . - 0 ID=cds-YP_010377120.1;Parent=gene-NBT03_gp117;Dbxref=Genbank:YP_010377120.1,GeneID:72551533;Name=YP_010377120.1;Note=A13L%3B similar to Vaccinia virus strain Copenhagen A12L%3B virion core protein;gbkey=CDS;gene_name=OPG138;locus_tag=NBT03_gp117;product=MPXVgp123;protein_id=YP_010377120.1 -NC_063383.1 RefSeq gene 121156 121368 . - . ID=gene-NBT03_gp118;Dbxref=GeneID:72551534;Name=OPG139;gbkey=Gene;gene_name=OPG139;gene_biotype=protein_coding;locus_tag=NBT03_gp118;old_locus_tag=MPXV-M5312_HM12_Rivers-122 -NC_063383.1 RefSeq CDS 121156 121368 . - 0 ID=cds-YP_010377121.1;Parent=gene-NBT03_gp118;Dbxref=Genbank:YP_010377121.1,GeneID:72551534;Name=YP_010377121.1;Note=A14L%3B similar to Vaccinia virus strain Copenhagen A13L%3B IMV inner and outer membrane protein;gbkey=CDS;gene_name=OPG139;locus_tag=NBT03_gp118;product=MPXVgp124;protein_id=YP_010377121.1 -NC_063383.1 RefSeq gene 121474 121746 . - . ID=gene-NBT03_gp119;Dbxref=GeneID:72551535;Name=OPG140;gbkey=Gene;gene_name=OPG140;gene_biotype=protein_coding;locus_tag=NBT03_gp119;old_locus_tag=MPXV-M5312_HM12_Rivers-123 -NC_063383.1 RefSeq CDS 121474 121746 . - 0 ID=cds-YP_010377122.1;Parent=gene-NBT03_gp119;Dbxref=Genbank:YP_010377122.1,GeneID:72551535;Name=YP_010377122.1;Note=A15L%3B similar to Vaccinia virus strain Copenhagen A14L%3B IMV inner membrane protein;gbkey=CDS;gene_name=OPG140;locus_tag=NBT03_gp119;product=MPXVgp125;protein_id=YP_010377122.1 -NC_063383.1 RefSeq gene 121763 121924 . - . ID=gene-NBT03_gp120;Dbxref=GeneID:72551536;Name=OPG141;gbkey=Gene;gene_name=OPG141;gene_biotype=protein_coding;locus_tag=NBT03_gp120;old_locus_tag=MPXV-M5312_HM12_Rivers-124 -NC_063383.1 RefSeq CDS 121763 121924 . - 0 ID=cds-YP_010377123.1;Parent=gene-NBT03_gp120;Dbxref=Genbank:YP_010377123.1,GeneID:72551536;Name=YP_010377123.1;gbkey=CDS;gene_name=OPG141;locus_tag=NBT03_gp120;product=A15.5L;protein_id=YP_010377123.1 -NC_063383.1 RefSeq gene 121914 122198 . - . ID=gene-NBT03_gp121;Dbxref=GeneID:72551537;Name=OPG142;gbkey=Gene;gene_name=OPG142;gene_biotype=protein_coding;locus_tag=NBT03_gp121;old_locus_tag=MPXV-M5312_HM12_Rivers-125 -NC_063383.1 RefSeq CDS 121914 122198 . - 0 ID=cds-YP_010377124.1;Parent=gene-NBT03_gp121;Dbxref=Genbank:YP_010377124.1,GeneID:72551537;Name=YP_010377124.1;Note=A16L%3B similar to Vaccinia virus strain Copenhagen A15L;gbkey=CDS;gene_name=OPG142;locus_tag=NBT03_gp121;product=MPXVgp126;protein_id=YP_010377124.1 -NC_063383.1 RefSeq gene 122182 123315 . - . ID=gene-NBT03_gp122;Dbxref=GeneID:72551538;Name=OPG143;gbkey=Gene;gene_name=OPG143;gene_biotype=protein_coding;locus_tag=NBT03_gp122;old_locus_tag=MPXV-M5312_HM12_Rivers-126 -NC_063383.1 RefSeq CDS 122182 123315 . - 0 ID=cds-YP_010377125.1;Parent=gene-NBT03_gp122;Dbxref=Genbank:YP_010377125.1,GeneID:72551538;Name=YP_010377125.1;Note=A17L%3B similar to Vaccinia virus strain Copenhagen A16L%3B soluble myristylated protein;gbkey=CDS;gene_name=OPG143;locus_tag=NBT03_gp122;product=MPXVgp127;protein_id=YP_010377125.1 -NC_063383.1 RefSeq gene 123318 123932 . - . ID=gene-NBT03_gp123;Dbxref=GeneID:72551539;Name=OPG144;gbkey=Gene;gene_name=OPG144;gene_biotype=protein_coding;locus_tag=NBT03_gp123;old_locus_tag=MPXV-M5312_HM12_Rivers-127 -NC_063383.1 RefSeq CDS 123318 123932 . - 0 ID=cds-YP_010377126.1;Parent=gene-NBT03_gp123;Dbxref=Genbank:YP_010377126.1,GeneID:72551539;Name=YP_010377126.1;Note=A18L%3B similar to Vaccinia virus strain Copenhagen A17L%3B IMV surface membrane protein%3B early function in virion morphgenesis;gbkey=CDS;gene_name=OPG144;locus_tag=NBT03_gp123;product=MPXVgp128;protein_id=YP_010377126.1 -NC_063383.1 RefSeq gene 123947 125425 . + . ID=gene-NBT03_gp124;Dbxref=GeneID:72551540;Name=OPG145;gbkey=Gene;gene_name=OPG145;gene_biotype=protein_coding;locus_tag=NBT03_gp124;old_locus_tag=MPXV-M5312_HM12_Rivers-128 -NC_063383.1 RefSeq CDS 123947 125425 . + 0 ID=cds-YP_010377127.1;Parent=gene-NBT03_gp124;Dbxref=Genbank:YP_010377127.1,GeneID:72551540;Name=YP_010377127.1;Note=A19R%3B similar to Vaccinia virus strain Copenhagen A1 8R%3B virion core associated DNA helicase%3B post-replicative negative transcription elongation factor;gbkey=CDS;gene_name=OPG145;locus_tag=NBT03_gp124;product=MPXVgp129;protein_id=YP_010377127.1 -NC_063383.1 RefSeq gene 125406 125639 . - . ID=gene-NBT03_gp125;Dbxref=GeneID:72551541;Name=OPG146;gbkey=Gene;gene_name=OPG146;gene_biotype=protein_coding;locus_tag=NBT03_gp125;old_locus_tag=MPXV-M5312_HM12_Rivers-129 -NC_063383.1 RefSeq CDS 125406 125639 . - 0 ID=cds-YP_010377128.1;Parent=gene-NBT03_gp125;Dbxref=Genbank:YP_010377128.1,GeneID:72551541;Name=YP_010377128.1;Note=A20L%3B similar to Vaccinia virus strain Copenhagen A19L;gbkey=CDS;gene_name=OPG146;locus_tag=NBT03_gp125;product=MPXVgp130;protein_id=YP_010377128.1 -NC_063383.1 RefSeq gene 125640 125987 . - . ID=gene-NBT03_gp126;Dbxref=GeneID:72551542;Name=OPG147;gbkey=Gene;gene_name=OPG147;gene_biotype=protein_coding;locus_tag=NBT03_gp126;old_locus_tag=MPXV-M5312_HM12_Rivers-130 -NC_063383.1 RefSeq CDS 125640 125987 . - 0 ID=cds-YP_010377129.1;Parent=gene-NBT03_gp126;Dbxref=Genbank:YP_010377129.1,GeneID:72551542;Name=YP_010377129.1;Note=A21L%3B similar to Vaccinia virus strain Copenhagen A21L;gbkey=CDS;gene_name=OPG147;locus_tag=NBT03_gp126;product=MPXVgp131;protein_id=YP_010377129.1 -NC_063383.1 RefSeq gene 125986 127266 . + . ID=gene-NBT03_gp127;Dbxref=GeneID:72551543;Name=OPG148;gbkey=Gene;gene_name=OPG148;gene_biotype=protein_coding;locus_tag=NBT03_gp127;old_locus_tag=MPXV-M5312_HM12_Rivers-131 -NC_063383.1 RefSeq CDS 125986 127266 . + 0 ID=cds-YP_010377130.1;Parent=gene-NBT03_gp127;Dbxref=Genbank:YP_010377130.1,GeneID:72551543;Name=YP_010377130.1;Note=A22R%3B similar to Vaccinia virus strain Copenhagen A20R%3B processivity factor for the viral DNA polymerase%2C VPF;gbkey=CDS;gene_name=OPG148;locus_tag=NBT03_gp127;product=MPXVgp132;protein_id=YP_010377130.1 -NC_063383.1 RefSeq gene 127196 127759 . + . ID=gene-NBT03_gp128;Dbxref=GeneID:72551544;Name=OPG149;gbkey=Gene;gene_name=OPG149;gene_biotype=protein_coding;locus_tag=NBT03_gp128;old_locus_tag=MPXV-M5312_HM12_Rivers-132 -NC_063383.1 RefSeq CDS 127196 127759 . + 0 ID=cds-YP_010377131.1;Parent=gene-NBT03_gp128;Dbxref=Genbank:YP_010377131.1,GeneID:72551544;Name=YP_010377131.1;Note=A23R%3B similar to Vaccinia virus strain Copenhagen A22R;gbkey=CDS;gene_name=OPG149;locus_tag=NBT03_gp128;product=MPXVgp133;protein_id=YP_010377131.1 -NC_063383.1 RefSeq gene 127779 128927 . + . ID=gene-NBT03_gp129;Dbxref=GeneID:72551545;Name=OPG150;gbkey=Gene;gene_name=OPG150;gene_biotype=protein_coding;locus_tag=NBT03_gp129;old_locus_tag=MPXV-M5312_HM12_Rivers-133 -NC_063383.1 RefSeq CDS 127779 128927 . + 0 ID=cds-YP_010377132.1;Parent=gene-NBT03_gp129;Dbxref=Genbank:YP_010377132.1,GeneID:72551545;Name=YP_010377132.1;Note=A24R%3B similar to Vaccinia virus strain Copenhagen A23R%3B intermediate transcription factor%2C VITF-3%2C 45 kDa;gbkey=CDS;gene_name=OPG150;locus_tag=NBT03_gp129;product=MPXVgp134;protein_id=YP_010377132.1 -NC_063383.1 RefSeq gene 128924 132418 . + . ID=gene-NBT03_gp130;Dbxref=GeneID:72551546;Name=OPG151;gbkey=Gene;gene_name=OPG151;gene_biotype=protein_coding;locus_tag=NBT03_gp130;old_locus_tag=MPXV-M5312_HM12_Rivers-134 -NC_063383.1 RefSeq CDS 128924 132418 . + 0 ID=cds-YP_010377133.1;Parent=gene-NBT03_gp130;Dbxref=Genbank:YP_010377133.1,GeneID:72551546;Name=YP_010377133.1;Note=A25R%3B similar to Vaccinia virus strain Copenhagen A24R%3B RNA polymerase%2C 132 kDa subunit;gbkey=CDS;gene_name=OPG151;locus_tag=NBT03_gp130;product=MPXVgp135;protein_id=YP_010377133.1 -NC_063383.1 RefSeq gene 136138 137667 . - . ID=gene-NBT03_gp131;Dbxref=GeneID:72551547;Name=OPG153;gbkey=Gene;gene_name=OPG153;gene_biotype=protein_coding;locus_tag=NBT03_gp131;old_locus_tag=MPXV-M5312_HM12_Rivers-137 -NC_063383.1 RefSeq CDS 136138 137667 . - 0 ID=cds-YP_010377134.1;Parent=gene-NBT03_gp131;Dbxref=Genbank:YP_010377134.1,GeneID:72551547;Name=YP_010377134.1;Note=A28L%3B major component of IMV surface tubules%3B p4c;gbkey=CDS;gene_name=OPG153;locus_tag=NBT03_gp131;product=MPXVgp138;protein_id=YP_010377134.1 -NC_063383.1 RefSeq gene 137718 138050 . - . ID=gene-NBT03_gp132;Dbxref=GeneID:72551548;Name=OPG154;gbkey=Gene;gene_name=OPG154;gene_biotype=protein_coding;locus_tag=NBT03_gp132;old_locus_tag=MPXV-M5312_HM12_Rivers-138 -NC_063383.1 RefSeq CDS 137718 138050 . - 0 ID=cds-YP_010377135.1;Parent=gene-NBT03_gp132;Dbxref=Genbank:YP_010377135.1,GeneID:72551548;Name=YP_010377135.1;Note=A29L%3B similar to Vaccinia virus strain Copenhagen A27L%3B IMV surface membrane 14 kDa fusion protein%3B binding to cell surface heparan;gbkey=CDS;gene_name=OPG154;locus_tag=NBT03_gp132;product=MPXVgp139;protein_id=YP_010377135.1 -NC_063383.1 RefSeq gene 138051 138491 . - . ID=gene-NBT03_gp133;Dbxref=GeneID:72551549;Name=OPG155;gbkey=Gene;gene_name=OPG155;gene_biotype=protein_coding;locus_tag=NBT03_gp133;old_locus_tag=MPXV-M5312_HM12_Rivers-139 -NC_063383.1 RefSeq CDS 138051 138491 . - 0 ID=cds-YP_010377136.1;Parent=gene-NBT03_gp133;Dbxref=Genbank:YP_010377136.1,GeneID:72551549;Name=YP_010377136.1;Note=A30L%3B similar to Vaccinia virus strain Copenhagen A28L;gbkey=CDS;gene_name=OPG155;locus_tag=NBT03_gp133;product=MPXVgp140;protein_id=YP_010377136.1 -NC_063383.1 RefSeq gene 138492 139409 . - . ID=gene-NBT03_gp134;Dbxref=GeneID:72551550;Name=OPG156;gbkey=Gene;gene_name=OPG156;gene_biotype=protein_coding;locus_tag=NBT03_gp134;old_locus_tag=MPXV-M5312_HM12_Rivers-140 -NC_063383.1 RefSeq CDS 138492 139409 . - 0 ID=cds-YP_010377137.1;Parent=gene-NBT03_gp134;Dbxref=Genbank:YP_010377137.1,GeneID:72551550;Name=YP_010377137.1;Note=A31L%3B similar to Vaccinia virus strain Copenhagen A29L%3B RNA polymerase%2C 35 kDa subunit;gbkey=CDS;gene_name=OPG156;locus_tag=NBT03_gp134;product=MPXVgp141;protein_id=YP_010377137.1 -NC_063383.1 RefSeq gene 139372 139608 . - . ID=gene-NBT03_gp135;Dbxref=GeneID:72551551;Name=OPG157;gbkey=Gene;gene_name=OPG157;gene_biotype=protein_coding;locus_tag=NBT03_gp135;old_locus_tag=MPXV-M5312_HM12_Rivers-141 -NC_063383.1 RefSeq CDS 139372 139608 . - 0 ID=cds-YP_010377138.1;Parent=gene-NBT03_gp135;Dbxref=Genbank:YP_010377138.1,GeneID:72551551;Name=YP_010377138.1;Note=A32L%3B similar to Vaccinia virus strain Copenhagen A30L;gbkey=CDS;gene_name=OPG157;locus_tag=NBT03_gp135;product=MPXVgp142;protein_id=YP_010377138.1 -NC_063383.1 RefSeq gene 139641 139769 . - . ID=gene-NBT03_gp136;Dbxref=GeneID:72551552;Name=OPG158;gbkey=Gene;gene_name=OPG158;gene_biotype=protein_coding;locus_tag=NBT03_gp136;old_locus_tag=MPXV-M5312_HM12_Rivers-142 -NC_063383.1 RefSeq CDS 139641 139769 . - 0 ID=cds-YP_010377139.1;Parent=gene-NBT03_gp136;Dbxref=Genbank:YP_010377139.1,GeneID:72551552;Name=YP_010377139.1;gbkey=CDS;gene_name=OPG158;locus_tag=NBT03_gp136;product=A32.5L;protein_id=YP_010377139.1 -NC_063383.1 RefSeq gene 139768 140205 . + . ID=gene-NBT03_gp137;Dbxref=GeneID:72551553;Name=OPG159;gbkey=Gene;gene_name=OPG159;gene_biotype=protein_coding;locus_tag=NBT03_gp137;old_locus_tag=MPXV-M5312_HM12_Rivers-143 -NC_063383.1 RefSeq CDS 139768 140205 . + 0 ID=cds-YP_010377140.1;Parent=gene-NBT03_gp137;Dbxref=Genbank:YP_010377140.1,GeneID:72551553;Name=YP_010377140.1;Note=A33R%3B similar to Vaccinia virus strain Copenhagen A31R;gbkey=CDS;gene_name=OPG159;locus_tag=NBT03_gp137;product=MPXVgp143;protein_id=YP_010377140.1 -NC_063383.1 RefSeq gene 140172 141074 . - . ID=gene-NBT03_gp138;Dbxref=GeneID:72551554;Name=OPG160;gbkey=Gene;gene_name=OPG160;gene_biotype=protein_coding;locus_tag=NBT03_gp138;old_locus_tag=MPXV-M5312_HM12_Rivers-144 -NC_063383.1 RefSeq CDS 140172 141074 . - 0 ID=cds-YP_010377141.1;Parent=gene-NBT03_gp138;Dbxref=Genbank:YP_010377141.1,GeneID:72551554;Name=YP_010377141.1;Note=A34L%3B similar to Vaccinia virus strain Copenhagen A32L%3B DNA packaging into virion%3B NTP-binding motif A;gbkey=CDS;gene_name=OPG160;locus_tag=NBT03_gp138;product=MPXVgp144;protein_id=YP_010377141.1 -NC_063383.1 RefSeq gene 141102 141647 . + . ID=gene-NBT03_gp139;Dbxref=GeneID:72551555;Name=OPG161;gbkey=Gene;gene_name=OPG161;gene_biotype=protein_coding;locus_tag=NBT03_gp139;old_locus_tag=MPXV-M5312_HM12_Rivers-145 -NC_063383.1 RefSeq CDS 141102 141647 . + 0 ID=cds-YP_010377142.1;Parent=gene-NBT03_gp139;Dbxref=Genbank:YP_010377142.1,GeneID:72551555;Name=YP_010377142.1;Note=A35R%3B similar to Vaccinia virus strain Copenhagen A33R%3B EEV envelope glycoprotein%2C needed for formation of actin-containing microvilli and cell-to-cell spread of virion%3B interacts with VAC A36R;gbkey=CDS;gene_name=OPG161;locus_tag=NBT03_gp139;product=MPXVgp145;protein_id=YP_010377142.1 -NC_063383.1 RefSeq gene 141652 142158 . + . ID=gene-NBT03_gp140;Dbxref=GeneID:72551556;Name=OPG162;gbkey=Gene;gene_name=OPG162;gene_biotype=protein_coding;locus_tag=NBT03_gp140;old_locus_tag=MPXV-M5312_HM12_Rivers-146 -NC_063383.1 RefSeq CDS 141652 142158 . + 0 ID=cds-YP_010377143.1;Parent=gene-NBT03_gp140;Dbxref=Genbank:YP_010377143.1,GeneID:72551556;Name=YP_010377143.1;Note=A36R%3B similar to Vaccinia virus strain Copenhagen A3 4R%3B EEV envelope glycoprotein%2C lectin-like%3B required for infectivity of EEV%2C formation of actin-containing microvilli%2C and cell-to-cell spread of virion;gbkey=CDS;gene_name=OPG162;locus_tag=NBT03_gp140;product=MPXVgp146;protein_id=YP_010377143.1 -NC_063383.1 RefSeq gene 142202 142732 . + . ID=gene-NBT03_gp141;Dbxref=GeneID:72551557;Name=OPG163;gbkey=Gene;gene_name=OPG163;gene_biotype=protein_coding;locus_tag=NBT03_gp141;old_locus_tag=MPXV-M5312_HM12_Rivers-147 -NC_063383.1 RefSeq CDS 142202 142732 . + 0 ID=cds-YP_010377144.1;Parent=gene-NBT03_gp141;Dbxref=Genbank:YP_010377144.1,GeneID:72551557;Name=YP_010377144.1;Note=A37R%3B similar to Vaccinia virus strain Copenhagen A35R;gbkey=CDS;gene_name=OPG163;locus_tag=NBT03_gp141;product=MPXVgp147;protein_id=YP_010377144.1 -NC_063383.1 RefSeq gene 142778 143464 . + . ID=gene-NBT03_gp142;Dbxref=GeneID:72551558;Name=OPG164;gbkey=Gene;gene_name=OPG164;gene_biotype=protein_coding;locus_tag=NBT03_gp142;old_locus_tag=MPXV-M5312_HM12_Rivers-148 -NC_063383.1 RefSeq CDS 142778 143464 . + 0 ID=cds-YP_010377145.1;Parent=gene-NBT03_gp142;Dbxref=Genbank:YP_010377145.1,GeneID:72551558;Name=YP_010377145.1;Note=A38R%3B similar to Vaccinia virus strain Copenhagen A36R%3B IEV but not CEV envelope protein%3B plays critical role for actin tail formation%3B interacts with VAC A33R and A34R;gbkey=CDS;gene_name=OPG164;locus_tag=NBT03_gp142;product=MPXVgp148;protein_id=YP_010377145.1 -NC_063383.1 RefSeq gene 143516 144322 . + . ID=gene-NBT03_gp143;Dbxref=GeneID:72551559;Name=OPG165;gbkey=Gene;gene_name=OPG165;gene_biotype=protein_coding;locus_tag=NBT03_gp143;old_locus_tag=MPXV-M5312_HM12_Rivers-149 -NC_063383.1 RefSeq CDS 143516 144322 . + 0 ID=cds-YP_010377146.1;Parent=gene-NBT03_gp143;Dbxref=Genbank:YP_010377146.1,GeneID:72551559;Name=YP_010377146.1;Note=A39R%3B similar to Vaccinia virus strain Copenhagen A37R;gbkey=CDS;gene_name=OPG165;locus_tag=NBT03_gp143;product=MPXVgp149;protein_id=YP_010377146.1 -NC_063383.1 RefSeq gene 144574 145407 . - . ID=gene-NBT03_gp144;Dbxref=GeneID:72551560;Name=OPG167;gbkey=Gene;gene_name=OPG167;gene_biotype=protein_coding;locus_tag=NBT03_gp144;old_locus_tag=MPXV-M5312_HM12_Rivers-150 -NC_063383.1 RefSeq CDS 144574 145407 . - 0 ID=cds-YP_010377147.1;Parent=gene-NBT03_gp144;Dbxref=Genbank:YP_010377147.1,GeneID:72551560;Name=YP_010377147.1;Note=A40L%3B similar to Vaccinia virus strain Copenhagen A38L%3B integral membrane glycoprotein%3B immunoglobulin-like%3B regulation of the influx of extracellular Ca2+;gbkey=CDS;gene_name=OPG167;locus_tag=NBT03_gp144;product=MPXVgp150;protein_id=YP_010377147.1 -NC_063383.1 RefSeq gene 146113 146778 . - . ID=gene-NBT03_gp145;Dbxref=GeneID:72551561;Name=OPG170;gbkey=Gene;gene_name=OPG170;gene_biotype=protein_coding;locus_tag=NBT03_gp145;old_locus_tag=MPXV-M5312_HM12_Rivers-151 -NC_063383.1 RefSeq CDS 146113 146778 . - 0 ID=cds-YP_010377148.1;Parent=gene-NBT03_gp145;Dbxref=Genbank:YP_010377148.1,GeneID:72551561;Name=YP_010377148.1;Note=A41L%3B similar to Vaccinia virus strain Copenhagen A41L%3B secreted protein reducing infiltration of inflammatory cells into the infected area;gbkey=CDS;gene_name=OPG170;locus_tag=NBT03_gp145;product=MPXVgp151;protein_id=YP_010377148.1 -NC_063383.1 RefSeq gene 146988 147389 . + . ID=gene-NBT03_gp146;Dbxref=GeneID:72551562;Name=OPG171;gbkey=Gene;gene_name=OPG171;gene_biotype=protein_coding;locus_tag=NBT03_gp146;old_locus_tag=MPXV-M5312_HM12_Rivers-152 -NC_063383.1 RefSeq CDS 146988 147389 . + 0 ID=cds-YP_010377149.1;Parent=gene-NBT03_gp146;Dbxref=Genbank:YP_010377149.1,GeneID:72551562;Name=YP_010377149.1;Note=A42R%3B similar to Vaccinia virus strain Copenhagen A42R%3B profilin-like;gbkey=CDS;gene_name=OPG171;locus_tag=NBT03_gp146;product=MPXVgp152;protein_id=YP_010377149.1 -NC_063383.1 RefSeq gene 147427 148017 . + . ID=gene-NBT03_gp147;Dbxref=GeneID:72551563;Name=OPG172;gbkey=Gene;gene_name=OPG172;gene_biotype=protein_coding;locus_tag=NBT03_gp147;old_locus_tag=MPXV-M5312_HM12_Rivers-153 -NC_063383.1 RefSeq CDS 147427 148017 . + 0 ID=cds-YP_010377150.1;Parent=gene-NBT03_gp147;Dbxref=Genbank:YP_010377150.1,GeneID:72551563;Name=YP_010377150.1;Note=A43R%3B similar to Vaccinia virus strain Copenhagen A43R%3B membrane glycoprotein;gbkey=CDS;gene_name=OPG172;locus_tag=NBT03_gp147;product=MPXVgp153;protein_id=YP_010377150.1 -NC_063383.1 RefSeq gene 148037 148261 . + . ID=gene-NBT03_gp148;Dbxref=GeneID:72551564;Name=OPG173;gbkey=Gene;gene_name=OPG173;gene_biotype=protein_coding;locus_tag=NBT03_gp148;old_locus_tag=MPXV-M5312_HM12_Rivers-154 -NC_063383.1 RefSeq CDS 148037 148261 . + 0 ID=cds-YP_010377151.1;Parent=gene-NBT03_gp148;Dbxref=Genbank:YP_010377151.1,GeneID:72551564;Name=YP_010377151.1;Note=A44R;gbkey=CDS;gene_name=OPG173;locus_tag=NBT03_gp148;product=MPXVgp154;protein_id=YP_010377151.1 -NC_063383.1 RefSeq gene 148355 149395 . - . ID=gene-NBT03_gp149;Dbxref=GeneID:72551565;Name=OPG174;gbkey=Gene;gene_name=OPG174;gene_biotype=protein_coding;locus_tag=NBT03_gp149;old_locus_tag=MPXV-M5312_HM12_Rivers-155 -NC_063383.1 RefSeq CDS 148355 149395 . - 0 ID=cds-YP_010377152.1;Parent=gene-NBT03_gp149;Dbxref=Genbank:YP_010377152.1,GeneID:72551565;Name=YP_010377152.1;Note=A45L%3B similar to Vaccinia virus strain Copenhagen A44L%3B 3-b-Hydroxy-delta5-steroid dehydrogenase;gbkey=CDS;gene_name=OPG174;locus_tag=NBT03_gp149;product=MPXVgp158;protein_id=YP_010377152.1 -NC_063383.1 RefSeq gene 149442 149819 . + . ID=gene-NBT03_gp150;Dbxref=GeneID:72551566;Name=OPG175;gbkey=Gene;gene_name=OPG175;gene_biotype=protein_coding;locus_tag=NBT03_gp150;old_locus_tag=MPXV-M5312_HM12_Rivers-156 -NC_063383.1 RefSeq CDS 149442 149819 . + 0 ID=cds-YP_010377153.1;Parent=gene-NBT03_gp150;Dbxref=Genbank:YP_010377153.1,GeneID:72551566;Name=YP_010377153.1;Note=A46R%3B similar to Vaccinia virus strain Copenhagen A45R%3B superoxide dismutase-like%3B virion core protein;gbkey=CDS;gene_name=OPG175;locus_tag=NBT03_gp150;product=MPXVgp156;protein_id=YP_010377153.1 -NC_063383.1 RefSeq gene 149809 150531 . + . ID=gene-NBT03_gp151;Dbxref=GeneID:72551567;Name=OPG176;gbkey=Gene;gene_name=OPG176;gene_biotype=protein_coding;locus_tag=NBT03_gp151;old_locus_tag=MPXV-M5312_HM12_Rivers-157 -NC_063383.1 RefSeq CDS 149809 150531 . + 0 ID=cds-YP_010377154.1;Parent=gene-NBT03_gp151;Dbxref=Genbank:YP_010377154.1,GeneID:72551567;Name=YP_010377154.1;Note=A47R%3B similar to Vaccinia virus strain Copenhagen A46R;gbkey=CDS;gene_name=OPG176;locus_tag=NBT03_gp151;product=MPXVgp157;protein_id=YP_010377154.1 -NC_063383.1 RefSeq gene 151509 152123 . + . ID=gene-NBT03_gp152;Dbxref=GeneID:72551568;Name=OPG178;gbkey=Gene;gene_name=OPG178;gene_biotype=protein_coding;locus_tag=NBT03_gp152;old_locus_tag=MPXV-M5312_HM12_Rivers-158 -NC_063383.1 RefSeq CDS 151509 152123 . + 0 ID=cds-YP_010377155.1;Parent=gene-NBT03_gp152;Dbxref=Genbank:YP_010377155.1,GeneID:72551568;Name=YP_010377155.1;Note=A49R%3B similar to Vaccinia virus strain Copenhagen A48R%3B thymidylate kinase;gbkey=CDS;gene_name=OPG178;locus_tag=NBT03_gp152;product=MPXVgp159;protein_id=YP_010377155.1 -NC_063383.1 RefSeq gene 152692 154371 . + . ID=gene-NBT03_gp153;Dbxref=GeneID:72551569;Name=OPG180;gbkey=Gene;gene_name=OPG180;gene_biotype=protein_coding;locus_tag=NBT03_gp153;old_locus_tag=MPXV-M5312_HM12_Rivers-159 -NC_063383.1 RefSeq CDS 152692 154371 . + 0 ID=cds-YP_010377156.1;Parent=gene-NBT03_gp153;Dbxref=Genbank:YP_010377156.1,GeneID:72551569;Name=YP_010377156.1;Note=A50R%3B similar to Vaccinia virus strain Copenhagen A50R%3B DNA ligase;gbkey=CDS;gene_name=OPG180;locus_tag=NBT03_gp153;product=MPXVgp160;protein_id=YP_010377156.1 -NC_063383.1 RefSeq gene 154412 155416 . + . ID=gene-NBT03_gp154;Dbxref=GeneID:72551570;Name=OPG181;gbkey=Gene;gene_name=OPG181;gene_biotype=protein_coding;locus_tag=NBT03_gp154;old_locus_tag=MPXV-M5312_HM12_Rivers-160 -NC_063383.1 RefSeq CDS 154412 155416 . + 0 ID=cds-YP_010377157.1;Parent=gene-NBT03_gp154;Dbxref=Genbank:YP_010377157.1,GeneID:72551570;Name=YP_010377157.1;Note=A51R%3B similar to Vaccinia virus strain Copenhagen A51R;gbkey=CDS;gene_name=OPG181;locus_tag=NBT03_gp154;product=MPXVgp161;protein_id=YP_010377157.1 -NC_063383.1 RefSeq gene 158917 159858 . + . ID=gene-NBT03_gp155;Dbxref=GeneID:72551571;Name=OPG185;gbkey=Gene;gene_name=OPG185;gene_biotype=protein_coding;locus_tag=NBT03_gp155;old_locus_tag=MPXV-M5312_HM12_Rivers-162 -NC_063383.1 RefSeq CDS 158917 159858 . + 0 ID=cds-YP_010377158.1;Parent=gene-NBT03_gp155;Dbxref=Genbank:YP_010377158.1,GeneID:72551571;Name=YP_010377158.1;Note=B2R%3B similar to Vaccinia virus strain Copenhagen A56R%3B EEV envelope and cell membrane glycoprotein hemagglutinin%3B inhibition of the ability of infected cells to fuse%3B interacts with VAC F13L;gbkey=CDS;gene_name=OPG185;locus_tag=NBT03_gp155;product=MPXVgp163;protein_id=YP_010377158.1 -NC_063383.1 RefSeq gene 160622 161533 . + . ID=gene-NBT03_gp156;Dbxref=GeneID:72551572;Name=OPG187;gbkey=Gene;gene_name=OPG187;gene_biotype=protein_coding;locus_tag=NBT03_gp156;old_locus_tag=MPXV-M5312_HM12_Rivers-163 -NC_063383.1 RefSeq CDS 160622 161533 . + 0 ID=cds-YP_010377159.1;Parent=gene-NBT03_gp156;Dbxref=Genbank:YP_010377159.1,GeneID:72551572;Name=YP_010377159.1;Note=B3R%3B similar to Vaccinia virus strain Copenhagen B1R%3B serine;gbkey=CDS;gene_name=OPG187;locus_tag=NBT03_gp156;product=MPXVgp164;protein_id=YP_010377159.1 -NC_063383.1 RefSeq gene 161596 163107 . + . ID=gene-NBT03_gp157;Dbxref=GeneID:72551573;Name=OPG188;gbkey=Gene;gene_name=OPG188;gene_biotype=protein_coding;locus_tag=NBT03_gp157;old_locus_tag=MPXV-M5312_HM12_Rivers-164 -NC_063383.1 RefSeq CDS 161596 163107 . + 0 ID=cds-YP_010377160.1;Parent=gene-NBT03_gp157;Dbxref=Genbank:YP_010377160.1,GeneID:72551573;Name=YP_010377160.1;Note=B4R%3B schlafen-like;gbkey=CDS;gene_name=OPG188;locus_tag=NBT03_gp157;product=MPXVgp165;protein_id=YP_010377160.1 -NC_063383.1 RefSeq gene 163333 165018 . + . ID=gene-NBT03_gp158;Dbxref=GeneID:72551574;Name=OPG189;gbkey=Gene;gene_name=OPG189;gene_biotype=protein_coding;locus_tag=NBT03_gp158;old_locus_tag=MPXV-M5312_HM12_Rivers-165 -NC_063383.1 RefSeq CDS 163333 165018 . + 0 ID=cds-YP_010377161.1;Parent=gene-NBT03_gp158;Dbxref=Genbank:YP_010377161.1,GeneID:72551574;Name=YP_010377161.1;Note=B5R%3B similar to Vaccinia virus strain Copenhagen B4R%3B ankyrin-like;gbkey=CDS;gene_name=OPG189;locus_tag=NBT03_gp158;product=MPXVgp166;protein_id=YP_010377161.1 -NC_063383.1 RefSeq gene 165122 166075 . + . ID=gene-NBT03_gp159;Dbxref=GeneID:72551575;Name=OPG190;gbkey=Gene;gene_name=OPG190;gene_biotype=protein_coding;locus_tag=NBT03_gp159;old_locus_tag=MPXV-M5312_HM12_Rivers-166 -NC_063383.1 RefSeq CDS 165122 166075 . + 0 ID=cds-YP_010377162.1;Parent=gene-NBT03_gp159;Dbxref=Genbank:YP_010377162.1,GeneID:72551575;Name=YP_010377162.1;Note=B6R%3B similar to Vaccinia virus strain Copenhagen B5R%3B palmitated 42 kDa glycoprotein located both on the membranes of infected cells and on EEV envelope%3B complement control protein-like;gbkey=CDS;gene_name=OPG190;locus_tag=NBT03_gp159;product=MPXVgp167;protein_id=YP_010377162.1 -NC_063383.1 RefSeq gene 166161 166667 . + . ID=gene-NBT03_gp160;Dbxref=GeneID:72551576;Name=OPG191;gbkey=Gene;gene_name=OPG191;gene_biotype=protein_coding;locus_tag=NBT03_gp160;old_locus_tag=MPXV-M5312_HM12_Rivers-167 -NC_063383.1 RefSeq CDS 166161 166667 . + 0 ID=cds-YP_010377163.1;Parent=gene-NBT03_gp160;Dbxref=Genbank:YP_010377163.1,GeneID:72551576;Name=YP_010377163.1;Note=B7R%3B similar to Vaccinia virus strain Copenhagen B6R;gbkey=CDS;gene_name=OPG191;locus_tag=NBT03_gp160;product=MPXVgp168;protein_id=YP_010377163.1 -NC_063383.1 RefSeq gene 166731 167279 . + . ID=gene-NBT03_gp161;Dbxref=GeneID:72551577;Name=OPG192;gbkey=Gene;gene_name=OPG192;gene_biotype=protein_coding;locus_tag=NBT03_gp161;old_locus_tag=MPXV-M5312_HM12_Rivers-168 -NC_063383.1 RefSeq CDS 166731 167279 . + 0 ID=cds-YP_010377164.1;Parent=gene-NBT03_gp161;Dbxref=Genbank:YP_010377164.1,GeneID:72551577;Name=YP_010377164.1;Note=B8R%3B similar to Vaccinia virus strain Copenhagen B7R;gbkey=CDS;gene_name=OPG192;locus_tag=NBT03_gp161;product=MPXVgp169;protein_id=YP_010377164.1 -NC_063383.1 RefSeq gene 167334 168137 . + . ID=gene-NBT03_gp162;Dbxref=GeneID:72551578;Name=OPG193;gbkey=Gene;gene_name=OPG193;gene_biotype=protein_coding;locus_tag=NBT03_gp162;old_locus_tag=MPXV-M5312_HM12_Rivers-169 -NC_063383.1 RefSeq CDS 167334 168137 . + 0 ID=cds-YP_010377165.1;Parent=gene-NBT03_gp162;Dbxref=Genbank:YP_010377165.1,GeneID:72551578;Name=YP_010377165.1;Note=B9R%3B similar to Vaccinia virus strain Copenhagen B8R%3B secreted IFN-g binding protein;gbkey=CDS;gene_name=OPG193;locus_tag=NBT03_gp162;product=MPXVgp170;protein_id=YP_010377165.1 -NC_063383.1 RefSeq gene 168230 168895 . + . ID=gene-NBT03_gp163;Dbxref=GeneID:72551579;Name=OPG195;gbkey=Gene;gene_name=OPG195;gene_biotype=protein_coding;locus_tag=NBT03_gp163;old_locus_tag=MPXV-M5312_HM12_Rivers-170 -NC_063383.1 RefSeq CDS 168230 168895 . + 0 ID=cds-YP_010377166.1;Parent=gene-NBT03_gp163;Dbxref=Genbank:YP_010377166.1,GeneID:72551579;Name=YP_010377166.1;Note=B10R%3B shope fibroma virus T4 protein-like;gbkey=CDS;gene_name=OPG195;locus_tag=NBT03_gp163;product=MPXVgp171;protein_id=YP_010377166.1 -NC_063383.1 RefSeq gene 169670 169972 . + . ID=gene-NBT03_gp164;Dbxref=GeneID:72551580;Name=OPG197;gbkey=Gene;gene_name=OPG197;gene_biotype=protein_coding;locus_tag=NBT03_gp164;old_locus_tag=MPXV-M5312_HM12_Rivers-171 -NC_063383.1 RefSeq CDS 169670 169972 . + 0 ID=cds-YP_010377167.1;Parent=gene-NBT03_gp164;Dbxref=Genbank:YP_010377167.1,GeneID:72551580;Name=YP_010377167.1;gbkey=CDS;gene_name=OPG197;locus_tag=NBT03_gp164;product=Hypothetical protein (Cop-B11R);protein_id=YP_010377167.1 -NC_063383.1 RefSeq gene 170038 170886 . + . ID=gene-NBT03_gp165;Dbxref=GeneID:72551581;Name=OPG198;gbkey=Gene;gene_name=OPG198;gene_biotype=protein_coding;locus_tag=NBT03_gp165;old_locus_tag=MPXV-M5312_HM12_Rivers-172 -NC_063383.1 RefSeq CDS 170038 170886 . + 0 ID=cds-YP_010377168.1;Parent=gene-NBT03_gp165;Dbxref=Genbank:YP_010377168.1,GeneID:72551581;Name=YP_010377168.1;Note=B11R%3B similar to Vaccinia virus strain Copenhagen B12R%3B protein kinase-like;gbkey=CDS;gene_name=OPG198;locus_tag=NBT03_gp165;product=MPXVgp172;protein_id=YP_010377168.1 -NC_063383.1 RefSeq gene 170988 172022 . + . ID=gene-NBT03_gp166;Dbxref=GeneID:72551582;Name=OPG199;gbkey=Gene;gene_name=OPG199;gene_biotype=protein_coding;locus_tag=NBT03_gp166;old_locus_tag=MPXV-M5312_HM12_Rivers-173 -NC_063383.1 RefSeq CDS 170988 172022 . + 0 ID=cds-YP_010377169.1;Parent=gene-NBT03_gp166;Dbxref=Genbank:YP_010377169.1,GeneID:72551582;Name=YP_010377169.1;Note=SPI-2%3B B12R%3B serine protease inhibitor-like%2C SPI-2%3B inhibition of the IL-1b converting enzyme%3B apoptosis inhibition;gbkey=CDS;gene_name=OPG199;locus_tag=NBT03_gp166;product=MPXVgp173;protein_id=YP_010377169.1 -NC_063383.1 RefSeq gene 172150 172599 . + . ID=gene-NBT03_gp167;Dbxref=GeneID:72551583;Name=OPG200;gbkey=Gene;gene_name=OPG200;gene_biotype=protein_coding;locus_tag=NBT03_gp167;old_locus_tag=MPXV-M5312_HM12_Rivers-174 -NC_063383.1 RefSeq CDS 172150 172599 . + 0 ID=cds-YP_010377170.1;Parent=gene-NBT03_gp167;Dbxref=Genbank:YP_010377170.1,GeneID:72551583;Name=YP_010377170.1;Note=B13R%3B similar to Vaccinia virus strain Copenhagen B15R;gbkey=CDS;gene_name=OPG200;locus_tag=NBT03_gp167;product=MPXVgp174;protein_id=YP_010377170.1 -NC_063383.1 RefSeq gene 174532 175587 . + . ID=gene-NBT03_gp168;Dbxref=GeneID:72551584;Name=OPG204;gbkey=Gene;gene_name=OPG204;gene_biotype=protein_coding;locus_tag=NBT03_gp168;old_locus_tag=MPXV-M5312_HM12_Rivers-177 -NC_063383.1 RefSeq CDS 174532 175587 . + 0 ID=cds-YP_010377172.1;Parent=gene-NBT03_gp168;Dbxref=Genbank:YP_010377172.1,GeneID:72551584;Name=YP_010377172.1;Note=B16R%3B similar to Vaccinia virus strain Copenhagen B19R%3B cell surface antigen and secreted IFN-a;gbkey=CDS;gene_name=OPG204;locus_tag=NBT03_gp168;product=MPXVgp177;protein_id=YP_010377172.1 -NC_063383.1 RefSeq gene 175656 178019 . + . ID=gene-NBT03_gp169;Dbxref=GeneID:72551585;Name=OPG205;gbkey=Gene;gene_name=OPG205;gene_biotype=protein_coding;locus_tag=NBT03_gp169;old_locus_tag=MPXV-M5312_HM12_Rivers-178 -NC_063383.1 RefSeq CDS 175656 178019 . + 0 ID=cds-YP_010377173.1;Parent=gene-NBT03_gp169;Dbxref=Genbank:YP_010377173.1,GeneID:72551585;Name=YP_010377173.1;Note=B17R%3B ankyrin-like;gbkey=CDS;gene_name=OPG205;locus_tag=NBT03_gp169;product=MPXVgp178;protein_id=YP_010377173.1 -NC_063383.1 RefSeq gene 179266 180339 . + . ID=gene-NBT03_gp170;Dbxref=GeneID:72551586;Name=OPG208;gbkey=Gene;gene_name=OPG208;gene_biotype=protein_coding;locus_tag=NBT03_gp170;old_locus_tag=MPXV-M5312_HM12_Rivers-180 -NC_063383.1 RefSeq CDS 179266 180339 . + 0 ID=cds-YP_010377174.1;Parent=gene-NBT03_gp170;Dbxref=Genbank:YP_010377174.1,GeneID:72551586;Name=YP_010377174.1;Note=SPI-1%3B B19R%3B serine protease inhibitor-like%2C SPI-1%3B apoptosis inhibition;gbkey=CDS;gene_name=OPG208;locus_tag=NBT03_gp170;product=MPXVgp180;protein_id=YP_010377174.1 -NC_063383.1 RefSeq gene 180518 181090 . + . ID=gene-NBT03_gp171;Dbxref=GeneID:72551587;Name=OPG209;gbkey=Gene;gene_name=OPG209;gene_biotype=protein_coding;locus_tag=NBT03_gp171;old_locus_tag=MPXV-M5312_HM12_Rivers-181 -NC_063383.1 RefSeq CDS 180518 181090 . + 0 ID=cds-YP_010377175.1;Parent=gene-NBT03_gp171;Dbxref=Genbank:YP_010377175.1,GeneID:72551587;Name=YP_010377175.1;Note=B20R;gbkey=CDS;gene_name=OPG209;locus_tag=NBT03_gp171;product=MPXVgp181;protein_id=YP_010377175.1 -NC_063383.1 RefSeq gene 181356 186998 . + . ID=gene-NBT03_gp172;Dbxref=GeneID:72551588;Name=OPG210;gbkey=Gene;gene_name=OPG210;gene_biotype=protein_coding;locus_tag=NBT03_gp172;old_locus_tag=MPXV-M5312_HM12_Rivers-182 -NC_063383.1 RefSeq CDS 181356 186998 . + 0 ID=cds-YP_010377176.1;Parent=gene-NBT03_gp172;Dbxref=Genbank:YP_010377176.1,GeneID:72551588;Name=YP_010377176.1;Note=B21R%3B putative membrane-associated glycoprotein%3B cadherin-like domain;gbkey=CDS;gene_name=OPG210;locus_tag=NBT03_gp172;product=MPXVgp182;protein_id=YP_010377176.1 -NC_063383.1 RefSeq gene 189199 189660 . + . ID=gene-NBT03_gp173;Dbxref=GeneID:72551589;Name=OPG005;gbkey=Gene;gene_name=OPG005;gene_biotype=protein_coding;locus_tag=NBT03_gp173;old_locus_tag=MPXV-M5312_HM12_Rivers-184 -NC_063383.1 RefSeq CDS 189199 189660 . + 0 ID=cds-YP_010377177.1;Parent=gene-NBT03_gp173;Dbxref=Genbank:YP_010377177.1,GeneID:72551589;Name=YP_010377177.1;Note=N1R%3B similar to Vaccinia virus strain Copenhagen B22R%3B VAC B15R-like;gbkey=CDS;gene_name=OPG005;locus_tag=NBT03_gp173;product=MPXVgp185;protein_id=YP_010377177.1 -NC_063383.1 RefSeq gene 190410 190940 . + . ID=gene-NBT03_gp174;Dbxref=GeneID:72551590;Name=NBT03_gp174;gbkey=Gene;gene_biotype=protein_coding;locus_tag=NBT03_gp174;old_locus_tag=MPXV-M5312_HM12_Rivers-186 -NC_063383.1 RefSeq CDS 190410 190940 . + 0 ID=cds-YP_010377184.1;Parent=gene-NBT03_gp174;Dbxref=Genbank:YP_010377184.1,GeneID:72551590;Name=YP_010377184.1;gbkey=CDS;locus_tag=NBT03_gp174;product=hypothetical protein;protein_id=YP_010377184.1 -NC_063383.1 RefSeq gene 191054 192367 . + . ID=gene-NBT03_gp175;Dbxref=GeneID:72551591;Name=NBT03_gp175;gbkey=Gene;gene_biotype=protein_coding;locus_tag=NBT03_gp175;old_locus_tag=MPXV-M5312_HM12_Rivers-187 -NC_063383.1 RefSeq CDS 191054 192367 . + 0 ID=cds-YP_010377179.1;Parent=gene-NBT03_gp175;Dbxref=Genbank:YP_010377179.1,GeneID:72551591;Name=YP_010377179.1;Note=N4R%3B ankyrin-like;gbkey=CDS;locus_tag=NBT03_gp175;product=MPXVgp188;protein_id=YP_010377179.1 -NC_063383.1 RefSeq gene 192603 194369 . + . ID=gene-NBT03_gp176;Dbxref=GeneID:72551592;Name=OPG003;gbkey=Gene;gene_name=OPG003;gene_biotype=protein_coding;locus_tag=NBT03_gp176;old_locus_tag=MPXV-M5312_HM12_Rivers-188 -NC_063383.1 RefSeq CDS 192603 194369 . + 0 ID=cds-YP_010377180.1;Parent=gene-NBT03_gp176;Dbxref=Genbank:YP_010377180.1,GeneID:72551592;Name=YP_010377180.1;Note=J1R%3B ankyrin-like;gbkey=CDS;gene_name=OPG003;locus_tag=NBT03_gp176;product=MPXVgp189;protein_id=YP_010377180.1 -NC_063383.1 RefSeq gene 194459 195508 . + . ID=gene-NBT03_gp177;Dbxref=GeneID:72551593;Name=OPG002;gbkey=Gene;gene_name=OPG002;gene_biotype=protein_coding;locus_tag=NBT03_gp177;old_locus_tag=MPXV-M5312_HM12_Rivers-189 -NC_063383.1 RefSeq CDS 194459 195508 . + 0 ID=cds-YP_010377181.1;Parent=gene-NBT03_gp177;Dbxref=Genbank:YP_010377181.1,GeneID:72551593;Name=YP_010377181.1;Note=J2R%3B secreted TNF binding protein;gbkey=CDS;gene_name=OPG002;locus_tag=NBT03_gp177;product=MPXVgp190;protein_id=YP_010377181.1 -NC_063383.1 RefSeq gene 195635 196375 . + . ID=gene-NBT03_gp178;Dbxref=GeneID:72551594;Name=OPG001;gbkey=Gene;gene_name=OPG001;gene_biotype=protein_coding;locus_tag=NBT03_gp178;old_locus_tag=MPXV-M5312_HM12_Rivers-190 -NC_063383.1 RefSeq CDS 195635 196375 . + 0 ID=cds-YP_010377182.1;Parent=gene-NBT03_gp178;Dbxref=Genbank:YP_010377182.1,GeneID:72551594;Name=YP_010377182.1;Note=J3R%3B similar to Vaccinia virus strain Copenhagen B29R%3B CC-chemokine binding;gbkey=CDS;gene_name=OPG001;locus_tag=NBT03_gp178;product=MPXVgp191;protein_id=YP_010377182.1 diff --git a/data/nextstrain/mpx/mpxv/ancestral/reference.fasta b/data/nextstrain/mpx/mpxv/ancestral/reference.fasta deleted file mode 100644 index 46d72f50..00000000 --- a/data/nextstrain/mpx/mpxv/ancestral/reference.fasta +++ /dev/null @@ -1,3288 +0,0 @@ ->reconstructed_ancestral_mpox -ATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTC -TAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTG -TGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTT -AATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTA -GTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTT -GTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGA -TCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAAT -TATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGCATAAGGATGTTGAT -AAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAA -AGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTT -TTTTTTTTTGTAAAACTTTTTTATGAGACAAAGAGAATACGAATAGTGATCATATCGTAT -CACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAAC -ATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTC -TGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGAC -ACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGC -CGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACAT -GTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGA -ACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATG -GGTCTTGATGTCGCTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACA -GTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCC -TGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGA -TGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGT -GTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTC -TGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGT -GACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGA -TGAGGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGAC -AATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTA -CCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATT -ATTTATGGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTT -ATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATA -AGAGATTGTATCCGTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTC -GACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATC -ATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAA -ATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGA -AGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACGGGATCACAATCTTT -ATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGT -CGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTT -AAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATA -TGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCC -GTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGATCCTTTGAG -AAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCG -CGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATT -ATTGTGAGATGTAAAGGTATCCGAACCACACGGCGTACATTGTGTATTAGTCTTGCTATC -ACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCT -GTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTT -TATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATA -ATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATT -TTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATA -CTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAA -TACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACG -AGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGA -AATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATAGGTGTGATACCGGATGTCTTCT -GTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATG -TCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAAT -ACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCC -CTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCC -GACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATG -ATGTCATTAACGACATCCGCCTTGTATATGATGTTTCTGTTTTCAAACACCAAGTCGAAT -ACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAG -GCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTAT -TCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTT -CCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGT -AATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCA -CAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTA -TCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGA -AGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGA -TCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTG -TAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGT -CCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAA -TAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTA -CTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAA -TGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGC -ATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAG -CAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACT -AATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACA -TTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTAC -CACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATT -TACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAA -ACTAACTTATAACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGA -CTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTT -ATGACTATTAACTCATTTCAAGAAAGGTGGGTGGAGAGAACTCTATATGACAGCTTGTGA -AACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATAC -ATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGT -TACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGA -ATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATA -CATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAAT -TATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAA -ATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAA -TTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGC -TTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATT -ACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATA -ACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATC -TTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAA -TCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGAT -ACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATA -GGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAAATCAACAAT -GTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACA -ATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATAT -AATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATC -TCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAG -AAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAA -TCCATGTTTTTTATAGTCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAA -CTGCTCATCGACAGCCATGAAATCTGCCGACTCCATGGTGCGAATCGCACTGTCTTATTC -GCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTA -CAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCT -TCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTT -TGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTA -TCCTCGTCTACTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAA -ATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATA -ATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACT -AGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTAT -CATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAG -ACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACA -ATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAA -TAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAA -ATGTCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAAT -AAAAATTATCATTATGTGTTTGTGTAGTTCTGCCCTATCATCTACATCACTGTCACTCTC -GCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTA -GTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATA -CATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTT -CGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCT -AGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAA -TAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGT -GATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATC -TATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTA -ACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATA -AACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGAT -AATCAGATCATTAGCCGATAGTGGTAACGCTATCGAAACAACATCGCCAGAAATTACAAA -CGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTT -ACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGG -TTATACAGGCATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACC -AGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTAT -TATTACGTGTTGTCTATTATCTGTTTATAGGTTCACTCGAAGAACTAAACTACCTATACA -AGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTA -TATGTATAAAAAAAATACTAAGTATGCGATGTATCCTGTATTATTTGTATTTATCTAAAC -AATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAAT -CTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAG -TCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAA -TCATCTTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCT -ATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGT -CAAATATTGTATCCATACATACATCTCCAAAACTATCACTTATACGTTTATCTTTAACGA -ACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACT -CCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAAC -TCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGAT -CTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTAGAGTCTT -TACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCT -GCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTT -AAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAG -TTATTATGTTATCGATGTCAACACATTCTACATTTTTTTAATCGTCTATATAGTATTTTT -CTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATC -AGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAA -CAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCT -TATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAAGAATGATTGTTTGACAATGT -CGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTT -ATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTA -ATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATT -ACGGTATGTTGTAACGACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTA -ATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCAT -ATTTATAATTTAGTACTTTGTATTTAGTATTTTTGGAATCATAAAAAAAGTTTTACTAAT -TTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCC -TGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACC -AAATGATATAAGACTAACAGTATGCATTATCCGAAATATTAATAACATTACATATTATAT -CAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTAT -CGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACT -TACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTA -CAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATT -AAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAA -TACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTA -TAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATT -AGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATG -TATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATG -CCGTACCCGTTTTAGAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAAT -AAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTT -GATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTA -GATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTT -TTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAG -TATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGG -TTTCATCTTCTTTGATGCCATCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATT -TCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGG -AACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCG -CGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCT -TGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTA -TTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATC -ATCAACTGATTCTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAAT -AATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTC -TGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAA -CATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATC -TATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATC -TATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGA -TACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTT -CAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGCTATACATGTATATCCGTTATT -TGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATT -ATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTT -AAGATAAGGTAGGCAAATGTTTATAGTACTAAGAATTGGGCAAGCATAAGACATGTCACA -AAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAG -GTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTT -TAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGC -CTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATC -GCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAA -TATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCC -GTGCGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTA -TCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTC -TATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATC -TATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGA -CGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGT -ATCCGACTCTGAATACAGATGAGAGATGATATACAGATGCAATACGGTACCGCAATTTCG -TGGTTGATAATCATCATACGCGTATCCGTACTCGTCATCCTCATAAAGAACACTGCAGCC -ATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTC -TATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACAC -CTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATT -TATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAAC -ATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTGTGTAATGG -ATTAGTGCCACTGTCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAA -AAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTC -TCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACAT -TTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTC -ATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAA -AAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCAT -TAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACCAGATG -TATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGC -CGCCACTACTACCCCCTTTAGAAGACATATTAATAAGACAAGTTTAACAATAAAATTAAT -CACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTA -GTCACAAGATCAATACTACCAACCTACACTATTATATGATTATAGTTTCTATTTTTATAG -GAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTT -ATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATT -AGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATAT -CGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCAT -GTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTAT -ATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTA -CTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTT -GGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAAT -TTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAAC -ACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATC -TATTAACCATTCTACTAGTGCAACACTATGCGACTCGATACAATAATAAAGTATACTACG -TCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTTTAGTATCGA -TAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTT -ATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCT -ATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTC -CCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAA -TAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACG -TAAACTATTACACAATTCTAAAATATAAAACGTATCATGGGCAGATAATAGTTTATCCAC -TATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAG -AATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCG -TTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATG -ACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACC -ATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATA -ATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATA -ATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTAT -TCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTT -CTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAA -TTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATT -GATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATT -ATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATT -TGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACT -ATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTT -TCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTT -CAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATC -AAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTC -TGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCT -TTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTG -TATACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTT -TTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTA -CGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTG -ATAATATGGATGTCGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAAT -CTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAA -GTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAA -CGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAAT -CATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATA -AATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATA -GAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCC -TTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTT -GTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAA -ATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACT -GAATTGATGAACGAATACCGACGGTGTTAATAGTAATTTACTTTTCATCTTTACATACTT -GGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAAC -CATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATAT -CGCTACGAATTTAAACAGAGAAATCAGTTAGGAAGAAAAAATTATCTATCATCATCATCA -TCTATTGGATAACGTCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCC -GTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGAT -ACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATGGTTCCATAAACA -GTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGAC -ATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCT -ATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTC -ATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAA -AAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGT -TTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGT -AACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAA -TGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAG -CTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGA -ACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCA -TGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATA -CTGAATCTACATCCAATTTTAGAAATTGGTCTGTGTTACATATCTCTTCTATATTATTGT -TGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAG -TACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACAT -CTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAA -CAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATAT -TATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATCTAACCTGTTCATATCCATGA -TTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTA -TTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTC -CGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCAT -CAATTTAGATAGAAACTTATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACT -TTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAA -TTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTA -GATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTT -ATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAAC -GCAGTAACATAGATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATC -GTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTT -ATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCCTC -GGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCG -ATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAA -TCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAA -CTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATAC -CGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATT -TCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTA -CGGACATAAACCATTGTATAATTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTT -CCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGCATTATAT -AGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTA -ATATTATGAATCATGGTTTTTACACATAGATCTACTACAGGCGGAACATCAATTATTATG -GCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATA -TAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCC -TTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCC -CATTGATAGAAAATATCACGCTTTCCATTCTCTTGAAGTACTATAAGTAATTATAATATA -ATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTCGACATTAATTCCT -TTTTAAATTTCCGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTA -CGTATCCTATCGTAGGCGATAGAACCGCTAAAAAGCCTATCGAATTTCTACAAAAGAATC -TGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAG -TAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTT -TTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTA -GATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTT -TAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAA -ATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTA -ATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATC -GATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATAT -TATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTT -CTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAA -TCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGT -CTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTG -GTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCA -ATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCAT -CATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCC -TCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGT -AACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAA -AATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCT -CATCGTAAAGGACGTTCTCGTACAGGACGTAACTATAAATTGGTTTATATTTGTTCAAGA -TAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCAT -ACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTAC -GAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGT -ATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCA -TTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGT -TGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACATTCGGGTAAAA -TTGTAGCATCATATACCATTTCTAGTACTTTAGGTTCATTGTTATCCATTGCAGAGGACG -TCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCA -AATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTA -AAGTATCTACGATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGA -ATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTC -TCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACA -CATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAAT -AGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAA -ATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATC -TTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCT -CTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATC -AATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCT -CCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACA -TACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTT -GAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGAC -ATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCG -ATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCA -CATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATT -CTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTA -TCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTA -ATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTAT -CCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCA -TGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCT -AAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTG -TGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTAC -TCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCA -TCTATAAATGTCACGCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATAT -TTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACA -CATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCC -GGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACA -CTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTA -TTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTC -ATGTTTATTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTT -TCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTG -AGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGAGGAGGACATATAGTATTCTTG -TATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATC -TTACTCAAAAGAGTAAGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATT -TTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTA -CACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTAT -TATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTT -CTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAAT -AGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAG -CCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGA -GCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGA -GAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACAT -CATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCA -GTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCAT -AATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCA -AAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTAT -CTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTAT -CAGCTATTGCATAATACAAGACACTATGACCGTTGATATCCGCCTTAAATGCATCTTTGC -TAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGT -CTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGCA -CCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATACATGGCTATCGCAAAACAA -CATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCAT -CAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTAGAT -TCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAAT -GGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGAT -GCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAA -ATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTA -GGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGG -AGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGCC -GTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTA -GCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTT -CCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTA -AAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATAT -ATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTA -GACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAG -TTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACA -GTACTATCGACGAAACTTTGATACGTTAGATCGGTGTACGTATATTTAGATGTTTTCATC -TTAGCTAATCCTGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTC -ATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATA -GAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTT -TGAATATTTTTATACGCTAATATACCGGCATTGATAAATCCCTGCAGACGATATGCGGAT -ACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATT -AACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAAC -TCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCT -ATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAG -ATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATT -GGGCAACGAATAACAAAATGCAAGCATCTTGTTAACGGGCTCGTAAATTGGGATAAAATT -ATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCCGGTT -GTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACC -TTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAA -AAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATG -CTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTT -TATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCAT -CTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAG -ATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAA -CGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACA -AAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGA -ATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAG -TACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAA -TACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTA -GATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGT -TCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCA -TGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAA -CTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTC -TTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTC -TTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCAT -CCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTT -CCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAG -TCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCC -TATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAA -CTTCATCCGTTTCCTTATGAAGATGATGTTTGGCACCTTCATAAATTTTTATTTCCCTAT -TACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTG -TTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGG -TAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGAT -CGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTC -CGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTG -GAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGAT -TATCGCAAGCAGCCAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTG -GAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACT -TACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCAT -GTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAG -AATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCC -AATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGCACTCATGATTC -ACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATT -GATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTG -TGAGATAGTCATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGA -TGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAG -AAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATT -GATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGT -CGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAG -TCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGAT -TTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATAT -AAACATCTTGATACTTTTTCTAGAAAAAAAATTGAATTGATGATATAGGTGTCTTCATAA -CGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTT -GAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACG -CGTGCTATGGATGGCATTATCCCGCGGTGTGGAAATGTACGTTATATAATCTACAAAATA -ATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCAT -ACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTT -GTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGT -AGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACA -ATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTC -GTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGT -TGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAG -CGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATG -TACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTA -AGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCT -TCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTT -ACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGTTTCCCCTATAATCT -TCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCT -ATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGT -TCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGC -GATTGCCTAGTAGGCGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTA -ATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATCCC -ATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGA -TCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATT -ATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAA -TTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATA -ATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTC -TGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGC -CACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCC -GTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATT -GTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCA -ATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCC -ACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTAT -AATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTG -TTTATCACAATGAAATATTTTGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCT -GGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCT -ATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAAC -ATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGAT -GTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATT -GGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATC -TCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGC -ACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAAT -AACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTT -ATTTTTTGTGTATTTTTGACGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATAT -CGTAGAATTGACTATTATATTGCCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGT -CGTATACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGT -TTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTT -TTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTT -CCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCA -ATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTT -TAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAA -ATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAAT -CGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTA -GGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTA -CTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAG -CCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGATAGTTTT -TTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGT -TTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTAC -AAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATA -CATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAG -ATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGA -TGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTT -CCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACT -TGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATA -GCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGT -TATCATCATTTTGTAATTGTGACATCATACTAGATAAATCATTTGTGAGATTGTTGTGGG -AAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAA -TGTTACGCACGTTCAACGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAA -ACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTA -ACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGT -ATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCA -TATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTT -CGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTA -CAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGCGATACTCCTTTGT -ATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAA -CGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAA -CCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACACGACAGTGTGGGTACAAA -TATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATACAGCCAACAAATATAAAA -TTACAAAAACTCTAACGACGTTCGTACACATCTTGATGCGGTTTAATAAATGTTTTGATT -TCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATT -CTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAA -AAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATT -AATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAA -ACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTAT -TTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGG -ATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACAT -CTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGCGTCA -CATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACCATTAAAATAAAA -ATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTAT -ACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAA -TCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATAT -TTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGT -CGCCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATTGCGTAGTGAGTACTA -TTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGT -ATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAA -TCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTG -GAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCG -ATCCTGTATTAACTATCTGTAAAAGCATATGTTGGCCGGGCGGAGCCGAACATTCTCCGA -TATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTT -CTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAG -CTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTG -TGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAA -ACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTT -GAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAG -TTTCCGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTA -ATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATG -ATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTT -AATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTG -TTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCC -GATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCA -TTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAA -CAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATG -TATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCC -GAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTC -TTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTG -TTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTC -TCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCC -ATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAAT -GTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCC -TTTAGATTGTTGTATAGAAATTTGGGTACTGTGAACTCCGCCGTAGTTTCCATGGGACTA -TATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATA -CCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCT -TTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCC -TTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAA -TCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGAT -AATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTAT -TGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGACAAACTATTAAC -TATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATT -CACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGT -CTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTC -TTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGT -TAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATT -AATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTT -ATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACA -AAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCT -AGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACC -TGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGC -ACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAA -GAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTC -AGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATC -ATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAA -GATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAA -ACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTAT -GGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCC -CATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCA -TCTGACTCATGGATTCATTAATATCTTTATAAGAGCTACTAACGTATAATTCTTTATAAC -TGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGC -AATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATAT -TTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCT -TGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCC -CTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATA -CTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAG -TAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGT -AGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATAC -GATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGA -TAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATA -CTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTAC -ATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATT -TCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTT -TTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTA -AAGATAAACCGCAAGAAAATTTATACGCATCCATCCAAATAACCCTAGCACCGTCGGATG -ATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCA -ACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCA -TAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAA -CAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGG -CTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTC -GCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGG -GACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTA -TCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAAT -CGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTT -CTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCT -GTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAAT -AATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATG -ATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCG -ACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTG -CCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAG -CTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTT -TCTATTTTTAAATTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCT -CAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATC -CGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGT -CGACTATCAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTT -GAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCC -AATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGT -TGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCA -AATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGT -CTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTA -TAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAAT -TCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGAT -CTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATC -CTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAAC -CGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCG -GGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTA -TTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAG -TACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAA -TTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTA -GTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGT -TAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATC -GCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTC -CATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTAT -CGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAA -TTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTA -GTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAAGCA -TGTCCAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTA -GACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTT -TTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTT -TCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAA -TGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTT -TCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCT -GTTGAAAATGAAACGGTGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTC -TGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAA -CAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATAT -TCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTAT -CTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCA -TCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTT -TATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATAT -TAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAA -TTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTT -TTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGT -ATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGAC -AATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATA -AAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCAT -CGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAA -ATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCG -TTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTT -TCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATG -CTATAAATGAATTCTCATTTTGTATCTGCACATACTCCGTTTTATATCAATACCAAAGAA -GGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAA -GGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGA -AGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTT -ATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGA -CTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGT -TTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTT -AAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATA -TGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATA -GTATTTGAGAAATATGTATACATGATATTATCATGAATTAGATATACAGAATTTGTAACA -CTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTT -TCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACT -ATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAG -ACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTGCATTAAACTTT -TCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTC -AATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATG -TTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTT -ATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATA -AATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCT -ATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATA -CAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGG -GAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAA -TTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAA -ATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAAT -ACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTA -GAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAA -AATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATT -TTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTG -CCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTC -CTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTT -TTTCACAGAGCGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGT -CTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTT -CAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAA -AATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGC -TCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTAT -TAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAA -TAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTA -CTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATC -TAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAG -GTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTAT -AAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCA -ACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTT -TGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGT -AAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAAT -GATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGAC -AGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTG -TTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGA -TCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTA -ACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTC -TAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATAT -CTATATAATTATTTTGTAAGATGATGTTAACTATGTGATCTATATAAGTAGTGTAATAAT -TCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTA -TAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAA -AATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATAT -AGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAG -CGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCAT -CTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGT -CAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGA -TAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGA -TAAAGGATAGTATATACTCGATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTA -TATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATGAGAGACTTGTCTCCTG -TTATCAATATACTATTCTTGTGATAATTTATGTGTGAGGCAAATTTGTCCACGTTCTTTA -ATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATA -GTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGAT -GAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTG -TGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCT -TTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATA -AAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGA -ATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTAT -TTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTA -CACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAAT -CTCTCCTAGTTATTTGGCAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAAT -AAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATT -TTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAG -CATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTCGGAGCTGTACACCATAGCACTAC -GTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTA -GTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTC -AGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAA -TAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCC -TATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTG -GAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATT -GCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTAC -AATCTCTACACGCGTGTCTAACTAATGGAGGTTCGTCAGCGGCTCTAGTTTGAATCATCA -TCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAA -CGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTT -TCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAG -TACCCTTAATCATATCACATAGTGTTTTATATTCTAAATTTGTGGCAATGGACGGTTTAT -TTCTATACGATAGTTTGTTTCTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTG -ATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACT -TTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATT -GTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATG -AGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTT -ATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTT -CATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAA -GTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCA -GAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTA -CGAGACATTGAAACTAGGATATATAAAATTTAAGTGAATGATTAGGACTACTACTCTAGA -AGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTC -AGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATG -TTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTG -TTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTA -AAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAAT -AGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATA -AATAGTTATTAGTGATAAGATAGTAAAAATAATTATTAGAATAGTAGTGTAGTATCATAG -ATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAG -AAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCA -ATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGG -ATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTAT -ACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTA -AGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACCGTGCATAAACTAA -CACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAG -GCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATA -TGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAA -GTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTG -CGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATA -GCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGG -TGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTA -CCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATA -AAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGC -TAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACG -ATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTA -TTAGTGATAGAACGTTTAACGAGGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAAT -ATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGAT -TTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATA -TCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGT -ATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAG -AGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGT -TTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGT -TAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGG -ATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAA -TCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAA -GAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGG -ATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATAT -TATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTT -GATAAATGGAAACTGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATG -CAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAA -TATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGAT -CTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAA -GTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAG -TATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGAT -GTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACA -CATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATC -TGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTA -TTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGAT -ATAAATATTATGGCAGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGA -AGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAAC -ACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGT -AGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAG -TTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAAT -ACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTT -TCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTAT -AATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGA -TACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGA -GACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACCGGTCCCGTTCCA -ATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTAT -GAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATG -TTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAA -TATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTA -TGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAAC -TTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAA -TATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAAT -ATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCG -TTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATT -AGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAG -AGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATC -TATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTT -GTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACC -TTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGT -ATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAA -ATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGA -CTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCT -ACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCT -ATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAA -CTCTGCTCCATTTAGTACCGATTCTAGATACAAGATCATTCTACGTCCTATGGATGTGCA -ACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATAC -TGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGA -ACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAA -TAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTT -CGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAA -GAGCTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGT -TTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGAT -TAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGG -AAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAA -CAGTGGACCCTTGATGACTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCAC -ATATGTTGACGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTG -ACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATA -ATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATGTATC -ATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCCAAATATCTTTACG -AATTACTTTACATATAATATCCTCATCAACAGTCACATAATTACCTGTGGTTAAAACCTT -TGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTC -TCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATC -CAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATAT -AGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATG -ACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCT -AAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAA -GTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTAT -TCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAG -CGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACAT -CTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACT -TGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTAT -ATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTT -ACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAA -CGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAA -TTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATC -TGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTC -TATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATA -TATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCC -ATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATT -AATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAA -ACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGA -CGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCC -TGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGA -TCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAA -ATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTAT -GATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGG -TTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGG -GTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAA -AATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGT -ATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTAT -TTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCA -TTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATACAAATAAGAAGGT -ACGGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATG -TGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGT -TTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATAT -TCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATG -GTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATG -TAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTT -TTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATT -AAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAAT -AATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGAC -AGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTG -AAGACATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACC -ATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGT -ACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGA -TTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTT -TTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATA -GTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTG -ATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATAT -CTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTA -TCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCT -ATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTT -GGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACA -TCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACAC -ATCTCTTCATCGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCA -GATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTA -GCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTA -AAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTA -ATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACA -TTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCA -TCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGA -GGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGC -AATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCA -ATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATG -AACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGT -TCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAA -CAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACC -ACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATC -TACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCT -ACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTG -TACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAA -CTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAA -CGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTT -GATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCA -TTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATAT -CTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCG -CCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACA -TAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGC -GAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATA -AGTTCATCGGGAATGACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATG -GATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCCAGATGATAT -GTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTA -ACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTT -TCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTA -AAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCAC -AATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGT -TTCTTAGCTTGTGATTTTTTCTTTTGCGGACATTTTCTAGTGACCAACTCATCTACCATT -TCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACG -AGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATC -AATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAA -CCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCT -ATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTAC -AACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCA -TCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATT -GATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACCACTTCTCTATCAATG -ATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACA -GGTGTGATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCT -TCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTT -AATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAA -AGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGCGTAATGTTTCCATAGACAGCTTCT -AGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCG -CTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAA -GTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTA -GCGTATTGAGAAGCATTTAGTGTAACGTATTCGATACATTTTGCATTAGATTTACTAATC -GATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGT -CTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTG -TACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTT -TGTTAACCGCTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTA -TCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATT -CCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTC -GGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCA -GCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATA -TCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATC -TCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGG -AATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCA -TTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTT -CTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGT -ACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTA -TCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATG -GTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAG -AGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTA -GAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTG -ACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAAC -ATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGT -ATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTT -TTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATA -ATCGCTTTCCAGACGACTCGAGCCTTTATTATAGATTTGTATCTCCTTTCTCTTTCGTAT -AGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCC -GGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATC -CAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCCTCGTTTCCTGTATTCTTTTTAAGA -TCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGC -CGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGA -ATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTA -CTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTG -TCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGG -TGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAA -AGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACA -CGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGAT -TTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACC -GAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGA -GAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAAT -AGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAA -TCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACC -GTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATA -TGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATG -ACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAA -ATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCT -GGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAAT -GATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAA -ATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCC -ACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGA -GAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTA -GGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTC -TCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACT -AATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGAT -ATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATG -TATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAAT -GAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTG -GAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCC -AACACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAG -CTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCT -GTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTA -TTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTT -AAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATC -ACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTCAACCAACCGAATGGAGTAAAATAA -ATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTC -TCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATG -GGCTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATG -CATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGAC -TTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGT -AGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATA -TTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAA -TAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAAC -TTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACT -AATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTAT -TTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATT -ATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAA -ATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAA -ACATTGTTTTTTATCATAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACAT -TACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTT -ATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAA -TTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACT -TCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATT -TTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAA -GTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTAT -ACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGT -TAACTCTTTCTTTTGATCGAGTTCGTCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTC -TACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTT -ATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATT -GCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGG -TATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAG -ATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAAT -TCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAA -AACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAG -AAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAA -TGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAA -AATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAG -AAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAG -GTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAG -CACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAA -CCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTG -GTGGATTCTCTACTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTC -TTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTA -AGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAA -ACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAAC -TATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATA -TTATTATAGCAGTAGCGAGAAAGCATCATACGAAAATAGATTCTATGTTTTTAATGACTG -CCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATAC -ATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATC -CATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGA -TGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTC -ACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTA -AGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAA -TTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATG -ATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAAT -CTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATT -TCTATGATCTGTCTTATATGAAGTCTATACAGCGAATAGATTCAGAATTTCTACATAATT -ATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTA -CAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAG -AAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTT -ATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAA -CTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACGAATTAAGATTTTAAAATTTA -AACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACG -GAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAG -ATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAACTCTAATGACCACATCTTTT -TTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAA -AAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAAC -AGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTC -TTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACT -ATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAA -ATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCA -TCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGT -TTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCCTGTATATCATCAGCT -GAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTA -GACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCA -TTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCA -TTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCC -TTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGCATATATTTCA -TTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATAT -AAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAA -TTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTC -TCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCA -TAGTCTATTAAGTGGTAAGTTTCGTACAAATACAGAATCCCTAAAATATTATCTAATGTG -GGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTT -GTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTC -TGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGAT -CCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATC -ATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATA -CAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGT -ATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAAT -GTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAA -CTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGT -TCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAA -ATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGT -AAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGT -ATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAAT -TATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTAT -CTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTG -TTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATAC -ATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTG -TTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCC -TTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAA -TACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATG -GAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAG -TATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGAC -AGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATAC -ACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATT -CTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAAT -AAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAAT -TATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGG -AAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGAT -TTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTA -ATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAG -TTAGATAGATGCGCTGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATA -CTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCG -GATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCG -AAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGA -AAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGT -GGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAAC -TACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTT -TATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTC -TAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAA -TGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACT -CACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACT -AACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGA -ATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAAT -AATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGAT -AAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAA -ATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAAC -ACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCAC -TAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATAT -TGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTG -TCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAA -ATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACG -TAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATAC -TAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAA -CTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTC -ATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATAT -AGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATT -TCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGT -GTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTA -ACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATG -CGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATC -CATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAG -TTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGAT -ATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATA -TGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTA -AATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAG -GTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATG -ATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATA -ACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTC -ATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATA -AATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATAT -CCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCG -TTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTA -GATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCT -ATATATTCTGCTATATTGTTGCTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTG -GTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAA -TCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATT -GGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCT -AGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATT -TCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCT -AGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAA -TTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTG -TCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTG -TAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCT -TTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACAT -TTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATA -ATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGG -CATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAGTTAA -TGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTG -CATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAA -AATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAA -ATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGA -TGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTAT -TTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGT -TGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATG -ACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGA -CTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACA -AACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATG -ACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCT -TTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTT -GAGCTCCCTAAACGGGATCCGCCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTG -GATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCA -CTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAAC -ACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAAT -TGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAG -TATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGC -GATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAG -TGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATA -AATCTGTATAATAAGATGCAAACATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAA -TTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGCAAAGAGATGATCGATTAT -ATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACT -AGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAG -TGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGC -AATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTA -AGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCA -AAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTA -TTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGC -ATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCG -AACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAAC -CATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGAT -GCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATAC -GTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGA -GATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTA -AAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTG -GAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTG -ACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTT -TATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGT -ATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTC -CATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACG -GATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGC -TGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGT -TATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTAT -TGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAA -TTATCAAATGTTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACT -TTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATG -CTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGAC -ATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGG -CACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTT -TTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGCGATATGTGATTTTTTAT -CAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGGCC -GTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCA -AATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAA -AACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCC -ACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACA -TTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCAT -AGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGA -TCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAA -CATATAATAGGCAGGAGATAGATATCCGTCATTGCAATATTCCTTCTCGTAGGCACACAA -TCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTG -ATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCC -TGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATC -GGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTGCTAGAAAAC -CTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAA -ATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATA -GTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGG -GCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTA -ACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATC -ATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAG -AACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAA -AAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGA -GACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCT -TCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAA -CTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGG -TTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATT -CCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTG -TTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTT -TTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAAT -ATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAAT -CTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACA -TCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGA -TCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATT -TTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCAC -TCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGT -GGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTC -TCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACT -TAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGC -TCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATT -TTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAACAATAATTAATTCTTTATTG -TTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTA -CAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAA -AATATTCTAACGATAATAGATACGGAACGGGACTATGGACGCATGATAAGAATAATTTTG -CAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGA -TAGGTATCGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAA -ACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTA -ATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTA -TGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTGCAGAAACCGAGATAGAAA -TAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAAT -ATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTT -AAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGA -GTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACA -GTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATT -AGATGGTGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAG -AGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCA -TGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGA -ATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGT -GAGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCT -ACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCC -GTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACC -TTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATAT -GAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCT -TAATAAGATAGTCCGCAACAAAGTAGTTGTTAACTTTGATTATCCTAATCAGGAATATGA -CTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTAC -TAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGAC -ATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTAT -GTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGA -GATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAA -TTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGG -TTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACA -AGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTG -TTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTA -AAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATC -GTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAG -AGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAA -GAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAA -TAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTT -CCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAAACAT -TATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAG -ATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTT -TACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATAC -TTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGCATCACAGAATGCAT -AAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAG -TTGTAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGA -TAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATG -CTACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATG -GTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAAT -GTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTA -TTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCAC -GAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGGACACGCTCTTAGGAGAT -TAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGT -ATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTA -ACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCAT -TATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTC -CGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATG -AATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGG -TTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCA -GTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCG -CTCGGCGAAAAGATCAGACCGCTAGATCTGTAATTGGTCCCAGTACATCTATCACCGTTA -ATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATG -CCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTA -ATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATAC -ATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTG -GAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAG -GAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAG -ATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTA -TGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTC -AAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAG -TATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCA -GCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAA -AGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATC -TGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTA -TCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATTTACGGTTTTGGGGTGACATTCA -AAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAA -TAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAG -TTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAA -ATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATA -ATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATA -TTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGG -GTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTC -TTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAA -GATCTCAATCTACTGATATCGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAA -TCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATA -CGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAG -ATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATA -AAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGC -CGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGG -ATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGG -TATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTA -GAATTACAAAAGAAACGGCTATCACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATA -CTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTA -CACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAAC -TTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCA -CTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTAT -GTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAG -ACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAAT -ATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACAT -TCATTGAGGACGAGGATAATATTAGATTTACTGTCTACCTAAATTTCGTTGAACCGGAGG -AATTGAATCTTAGTAAGTTTATGATGGTTCTTCCGGGTGCCGCCAACAAGGGCAAGATTA -GTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAA -AGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGG -AGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCG -CTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGT -ACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTA -ATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAG -CATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCC -ACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGG -GTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGG -AGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTC -TTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGT -ATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCA -TAGCCCCGCTTCTATTTACTCCCGCAACACAATGAACCAACACGGGCTCGTTTCGTTGAT -CACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTAT -CATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCA -TCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTT -TATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTC -TGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTT -ATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTA -GAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTA -TTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTA -ATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGG -ATAGCAAAACAAAATTAGAAAGTGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATA -TATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGA -AAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGG -CGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTA -ATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTA -TGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTA -ACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAAC -ATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAA -ATCAGTGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCT -ATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGA -TCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTT -TCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCA -TCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCTGATAAGCTAACATCATAC -CCTCCTGTATATGTGAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTA -TTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTC -AAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACA -TATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGT -CTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAG -TGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCC -TTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCA -TTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTT -TCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCGCCGCCGCCATT -TAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCAT -TGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTG -TTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGA -ATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAAT -GGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGA -GTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATT -TTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAA -ATCTTAATATCTTCGTCACACGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGT -TTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGTATGTATTGGAGCCATT -GTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCG -CCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTT -CTAAGTTCTAATGTGATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTG -TATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTA -ACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTT -TTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACT -AACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGAT -ACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCA -GAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGA -ATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAA -GACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTC -AAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCA -TCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCA -TAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTC -ATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTT -TTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACA -GGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAG -ATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGAT -AGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAA -TATACGTACTTGATATCTAAGAAATCCTTAATGATAATAGGAATGGATAATCCGTCTATT -TTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGT -CTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTT -TCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAAT -TCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTA -ACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTA -AAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGAT -AAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATACGAAAAA -ATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAAT -CTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTA -TTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGAT -TTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAA -CAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTA -TACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGAGA -AATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGG -TCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCAT -CTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATA -ATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACT -AAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAA -TATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGAC -ATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATG -GTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAG -GTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTA -TCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACT -AAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAA -AAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTT -ACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAA -CATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAG -GCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTAC -GGAAAAATGCATGTACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATAT -AACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGAT -TCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGT -AAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACAC -ATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACAT -GAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGAT -TCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATACGAATGTATC -AAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTA -TATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATA -GCGTTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGA -GCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTA -TCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACG -GATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAA -ACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTAT -GGCATTGATAATGTCTATATTTAAACGCCATCCAAACAATACCATTTTTTCAGTGGATAA -GGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGA -TCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCGAGTATAGCCGA -ACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCC -CCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGA -TACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGC -TTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCA -ACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAG -AATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTA -AACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTA -TTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTA -AGGTACATGGTCTAGATGTAAAAAATGTACAGTTGGTAGATGCTATAGATAACATAGTTT -GGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTAT -CGACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAG -AATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAAT -ATTTTCTAGGATCTGGTGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAA -AGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTC -CATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTC -CAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTA -AACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGATGGCA -TTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTT -ATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGG -CAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAA -TCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATC -GGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCG -ATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGG -GACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAA -ATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTA -TAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGA -TTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATA -CACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCT -TAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAG -AAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCA -AAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCCGCCA -ACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAG -GGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCA -AAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTG -CTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATG -CTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCA -AGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTG -TCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATT -ATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTT -CTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATA -AAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAA -AAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTG -AATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTG -TAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCAT -CTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTA -AATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTA -AGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAAT -TCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTA -ATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGT -TTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTA -TCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTT -TCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTA -CTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAG -GATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAAT -CACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAA -TATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTT -CAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGA -TGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTAT -GATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCA -TCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCA -GTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTA -TTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATAC -AAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCG -TTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAA -AAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTA -CTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAG -CCAGTTGGCTGCTACGAGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGA -AACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATG -GAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTT -CATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAG -ACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACG -CGATTTACTGGGATAAGATTTCCAAGTTACTGCTGCAGCATATAACTAAACACGTTAGTG -TTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGG -TAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGAT -CATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTC -AAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCT -ATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGA -CAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATT -GATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATA -GTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACG -GCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAA -TGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAG -TCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATG -GATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCA -CTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGT -ACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCATGATAATATA -GAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAA -CGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAA -GACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTC -GATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTA -TGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGA -ATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAAT -AAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGA -GGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATA -ACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTC -TGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTA -GAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGAC -GGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTT -AAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATC -ATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAA -ACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAA -ACCGCAACTGGAAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTT -GTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATC -GCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGT -GGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGA -AGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACT -AATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTG -CGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCG -TACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATAT -AGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATG -AAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACT -CTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGA -TATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCC -AAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAG -AAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCT -CCGTAAATATATGCCATATATTTATAGAAGATATCACATATCTAAATGAATACCGGAATC -ATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCT -ACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCAT -ATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTT -AAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATG -GGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCC -ACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGT -CGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACT -GGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGA -TCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAG -ACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAAC -GAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATG -CCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTA -GTATATTGTCACATGTCTAAACTTCAAGAGAGAGATTATATGATTACTAGACGACAGCTA -TGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAA -CTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCA -AATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGT -TCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATAC -TTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATAT -TCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACA -TTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAAT -TCTCCTGAAAACGATGATGGCAGTCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCT -GAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTT -TCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGCCGATATTTCT -GAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACG -TCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAG -CTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAG -ATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAA -TTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTT -AAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATT -GTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATAC -GAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTT -AACTTTCGTAAAGAATATAACGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGA -AATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGT -TGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAG -AAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCG -GCGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATT -ATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTA -TTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCG -ATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCG -CCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCG -TTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGC -GAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATC -AGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAAT -CTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTC -TGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGA -TAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGA -GTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTC -TAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTG -ATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAAT -AATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATT -CCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCC -ATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAG -AAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTG -GATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGA -AATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAA -ATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATAT -TTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAG -ACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAA -GAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAG -TATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGT -TGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTG -GTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAA -GTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTG -ATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGT -TGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAA -ATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTA -ATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACG -ACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGT -TAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGA -TAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAAC -TAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACA -GGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAG -AATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTT -ATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCG -TTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTT -CTTTGTTGGAAGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCA -TGAAATAAAGGATCTAATATTTTTAGATCCGAATTCAGGTAATGGACTCCAATACGAAAT -TGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTA -TGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCAT -CGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGT -ATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGG -AATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGAT -CGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCGATCGGTGAGAAGTCTT -TTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAA -ATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCAT -TAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAA -CGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATG -TCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAG -AAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAG -CCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAA -AGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGA -CTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTT -TCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTT -CTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTT -TAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTC -TTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATG -ATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTG -ACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACAT -CATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGA -CTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATC -CTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAG -CCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATA -CTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTAT -GACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAA -AAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCT -CTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCA -ATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAG -TCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATC -CTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCA -TCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTG -ATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTA -ACTAGTCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAA -AGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTA -TTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCC -TTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTT -TTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCAT -TTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCT -CTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAAT -GGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTG -AGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTG -AGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATC -TTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAA -AGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAG -TAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCT -GGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATT -TCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATC -TTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACC -AATTGTTTTTGTACATAATAGATTGGATGATTGACATCCATGGTGGAATAAACTACTCGA -ACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAAT -ATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGT -TCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTA -ACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGA -TCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACG -TTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGT -GATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAA -AACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTA -GTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCA -TCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAA -CCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCG -TCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCCGTA -TTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACT -GTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGT -TTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAAT -TCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGA -TTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCT -TCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCA -TTAGGAGTTAGACCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAA -GCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACA -CCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGTACGTAA -CCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGC -GCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCGGGCCCATCG -TTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTA -TCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATG -ATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAA -TATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTC -TTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATA -AAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAAT -CCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAA -TAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCT -TAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTT -CTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTC -GCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCT -CTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGA -TCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATT -TTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAA -AAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTG -CTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTT -TACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGC -CTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTC -CATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCG -CAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTAC -CTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGA -TACTATACCGTTGTGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGT -ATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCC -TGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCG -TCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGA -TTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTT -CTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAAC -AATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAG -CAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCA -ACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAG -CTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCC -AGGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATC -CACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGA -TACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAA -AGCCGGTGTAACATTCTCCACCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACA -TCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCA -ATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACA -CCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAA -TCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCT -GAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTC -TAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAG -AGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAAT -AAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTC -TCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCG -TAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTT -GCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAA -TACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAA -TAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAG -TCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGT -CACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAG -AAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTC -TATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGT -TAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCA -ATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTT -TGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAG -CCCCTGCGGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAG -ACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAG -TATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTT -CCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTAC -TTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTA -TACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGC -ATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGA -GATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGT -GTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTA -CAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGT -TGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGA -ACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGCA -GACAGCCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGTCGTGGTTTT -AGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGC -TGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGCCATC -ATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTT -AGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAG -ATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCC -ATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATT -ATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCA -CTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACT -CATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAA -CGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTAT -AACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAG -CAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATC -GAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCAT -CTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATAT -CGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATA -TCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATAT -TCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTT -TGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGAT -TCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATC -AGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGA -AACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGT -TGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAA -GAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAG -TCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTA -GATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGAC -GCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTA -TCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAAC -ATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACC -GATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATAT -TTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTC -TCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGAT -GCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTAT -AGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTC -TTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCA -TATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAA -CGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCAATAACATTTTTTG -TAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATC -CATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTG -GAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACT -CTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCT -TTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTT -TATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCAC -CAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTT -CCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACA -TTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCT -CAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAA -AACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTAT -TATATTTCCCCAAAGGATCAATGCATGTAAACATTATGCCGTTATCATTAATAAAGACTT -CTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAAT -TAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAA -CAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGG -CAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAG -ATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTAT -TAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGA -TAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTAT -CTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCAT -CGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGT -TTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACG -ACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTT -TTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTT -GTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGT -ACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGT -CACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCT -GAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCT -TATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTA -ATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATAT -TTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAG -TGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGAC -TCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTA -AGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGG -GAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGT -AGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTC -TTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTC -GACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATA -GCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTC -TTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATC -ATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTAT -TACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGT -CAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAAT -CTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTA -AATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAA -TTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAAT -GAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAA -CGCGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACG -ACTCATTTCGTTTATCATTATTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTT -GTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGG -CTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAA -AGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTA -CAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCAC -CATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTAT -AATAGTTTATCATACTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGT -CAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCG -CTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATG -CTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATAC -GTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATG -ATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGC -TAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTG -TGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTA -TGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTG -CGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCT -TAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACG -CAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGA -TAATGGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTAT -ACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGAT -CAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATG -TAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGC -TTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGA -TAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTA -TACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGA -GCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAG -ATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTG -AAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAG -GTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGAT -TATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAG -ACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCG -TAGATCTTTGTTCCTTCGCCAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTAT -TTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAG -GATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCA -GTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGA -AGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACT -GTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATG -GCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGT -CAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAAT -CTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAA -TAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATT -TCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAA -ATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTG -GAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTG -GATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCAC -GTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCAT -CTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGG -TTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAA -CTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAG -GCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTA -ATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGC -CAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTA -GTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGAT -TCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCA -CCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGA -TTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACT -TCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAG -ATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGAT -AATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACAGAAGTT -AATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAG -GACTTGGATGTTTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATAT -CACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATT -ATCGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATC -ACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTA -GGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAA -CGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAA -TCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTT -TAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTT -CTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTAC -CAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTG -TTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAG -ACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCAC -ATGCGCCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTG -CATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTT -CGATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGC -TAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATC -CTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATT -CGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGC -GACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATA -ACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGAT -TCAACAATGACAAGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATT -GGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAAT -TAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCA -TGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAAT -CAAAAGAATGATTCCAGCGATTAGCACGCCGGAAAAATAATTTCCAATCATAAGCATCAT -GTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATA -TAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAA -AATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTA -TCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCA -CCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGG -TTTACCAACAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAAT -GATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCAT -GTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTT -AGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGA -CGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTAC -GTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTT -TAACGCTAAAGAGTTAACGTTAATCGTACACCCAACGTATTTACATCTAGTTCTTTGAAC -ATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCA -ACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCA -ACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGT -AAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTT -GGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAA -ACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTC -TGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACA -TTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTG -CCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTC -GTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATG -AATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGA -CATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATA -CATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAA -TACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGT -AACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCA -ACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGT -ACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGA -ATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATT -GCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTA -CCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAAT -AGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAG -ACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAA -TCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGAT -TGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCA -TCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAA -GATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCT -TTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAAT -ACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAAC -AACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCT -TCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACG -TCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTA -TCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACA -TCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGT -TAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAG -ACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTT -GGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTA -TTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTA -TTGTAACAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATACAGT -AGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGA -TGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAG -AAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAAT -TTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCT -TTTCGGACCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGT -CAAATCAATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCAC -TGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATAT -GCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGT -ATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCA -ACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCGGAAACA -TCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAG -AATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCC -AGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATC -TTAACCAATTTAGACTGACAGGCAGAACACGTCATGCAATCATCATCGTCATCGATAACT -GTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATT -TAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATA -TCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATC -TTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTT -GTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTG -TAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATA -TTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCT -GATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCT -GTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATA -GGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAA -AATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGC -GTCTTTATTTATTCGAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAA -ATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGAC -TTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATAC -CAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTAT -TTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAA -CGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTT -AAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTA -GATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATA -TTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAA -GTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACT -AGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGA -AAGTATTTCTCTAAGGTTGGTAGTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATT -AATGAGTGCGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAA -CGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAA -GCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTA -AATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGA -AACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTC -GAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGA -AGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTG -GGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACG -TCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCA -TACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGA -TCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGA -CTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAG -ATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAA -TTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTC -TACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGCG -ATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTG -ACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACA -TCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCAC -AAGTGAAATGTTGTCATTATTTCGATATAAACTCAGATAATAGCAATATTAGCTCTCGTA -CAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATA -AGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAA -ATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTA -ATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTA -TAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAA -CATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATG -AAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGT -TGTTCGAGGATATCATCCAAAACGAGTACTTTAAAGAAGTAGCTAATGTTGTAAACCATG -TACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACG -ATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGT -TGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGG -GGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTA -AATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATA -TAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGA -TTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGT -TTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATT -GCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAAT -TATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAG -TATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGT -AATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCA -TTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAA -GTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGT -AGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAA -CTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCG -CCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAA -GACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGA -ATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGC -GATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATA -CATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGA -GTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACT -AAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTC -TAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTT -TGAGACGTTGGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCAT -GAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGG -ACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTA -TCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATT -TTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCA -ATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATC -TCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGA -AAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAAC -AGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATG -TGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGT -AGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAG -ATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGA -GTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGT -CATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAA -ATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGA -ATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAG -AGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACG -AAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAA -GGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATT -AATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCA -GAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAA -CTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATT -AGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAG -AACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATA -TACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAA -GGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAG -AACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGA -AAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTAT -ATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAA -GGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCCATCGATGCATATAT -GCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATC -GGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATC -CAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGC -AACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAA -ACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGCGC -AGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATAT -TTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATG -TTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGT -ATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCC -TCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATA -TTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTA -TTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAG -GTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGT -GGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCT -GTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATCT -TCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAG -GTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACT -TTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTC -CGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCC -TCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCT -CCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTT -TTTTTTTTTTTTTTTTTTCTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATC -TCTACGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCAT -GCCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTC -AATAACTTTAGCACGTTGTCTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGA -TTCCCTGGCACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAAC -TAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTAC -CACGTCTGTACTCGGCGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCA -TGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGA -AATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACA -CTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCC -TGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGCAAGTTAC -TAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCAT -CCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTA -CCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCA -TGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTCCGCAGTCGTTCAAC -TGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACT -CAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCC -TCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAG -TGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAG -ATCTCTAACGTGTCGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCT -ATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACT -AATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCAT -ACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATC -GTCGTCGCGTTGTTTTAGCCACATACGACTGAGTTCAAGTTCTCGTTGACAAGATCCATC -TACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTC -CATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGA -ACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCT -GTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTT -ATCACTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTT -AAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATT -AATGACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATT -AGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGG -ATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAAT -ACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCAT -CAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGG -AGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAG -GATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTC -ATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTT -TTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTT -AAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGC -ACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAG -GAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCT -AAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAAC -AAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATGTTAAAAAATCTTGA -TAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAAC -TGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATT -AAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTAT -ACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATT -ACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCA -TAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTT -CGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTA -TAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTGGATGGACAGT -AGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGT -ATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACA -ATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCT -TATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCT -CTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCCGGTATCGGAGTGGG -TTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCCATCAT -ATCATCATCTTCGATATTTATTTTGCTATCTTGATGATGTCCTGTATCAGTTGCATTTTC -AGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAA -ATGTATGTGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATC -GTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATC -ATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTC -AATAGTATCGAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACT -AAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCT -ACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCGATCTCTTTATTATG -AAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCA -TAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAA -TTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATC -ATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATAT -TATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAA -TGTTTTAAATTTTGTATTTAATGATCCATCATCATACGCTAGCATGGTCTTGTGATATTC -ATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCT -ATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTT -TCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTAT -CATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCGTTGGTACAATTCC -GTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAAT -TGAACAAAAGAGTTAAGTTACTCATATGGACGCCGTCCAGTCTGTACATCAATCTTTTTA -GCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACT -TCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATC -TTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTGTCGTCTCCATAGGCT -TTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCA -GTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACA -GATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATA -TCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTT -CTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGAT -ACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTG -TCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATAC -TCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAG -TAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGAT -AGAGAGTTCATTTATAATCTATTAGAAGCTGACAAAATTTTTTTACACGCGTCAGACAAT -GCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAAC -CTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACAAACAAC -ATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATG -TGATTATGAATATTGGCTATTAGAGCACCTTCTAAGAAATCTATAATATCTTTGAAACAC -GATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAG -ATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTA -TATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTT -ATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATAT -TCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACA -GAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCG -TGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTA -TGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCC -TCATTGACAGCTGTAGATGTATTAGACAAAACTACTCCAATGTTTAACAAGGGCCATTTT -ACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACG -ATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGA -TTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAG -TAATTCATGTACTACGGATAATGTAGACGTGTATTGCACATCGATATCTTTATTATTAGA -TAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATA -TAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCT -GTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCC -AAAAAGTCGGCAGCTGACATTTTTAACATGGCATCTATTTTAAATACACTTAGGTTTTTA -GAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAA -CATAAGGGAATGTCATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTG -TCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGAT -CTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCA -ATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAA -GTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTAT -AATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAAT -TTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTT -ACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACAT -ATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTG -GATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACA -GGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGC -GTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATA -GACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGT -TTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCG -ACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCC -TGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAA -ACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGT -AAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTT -AATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTT -ACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAG -AACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACG -ACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGA -ATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTAT -CTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACG -AGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGG -TTGCGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGG -GTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCG -CTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATT -ATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATC -AAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCG -CTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATG -TTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATG -CCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAAC -ATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCT -AGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTA -AGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATT -AGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATA -TACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTT -AAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGC -CATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTA -TGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAA -AATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAG -CTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAG -TATTTGTACCGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCAT -GTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAA -CGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAA -TCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGG -CAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTA -AAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGA -GATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTA -TATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCAT -GACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAG -CGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATAT -TTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGA -ATCCAATGTCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCT -GCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAA -TGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTC -CAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGC -AGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGCGACGATTA -TCTTAATAAGCAACAAGATCATGAACACGATGATATAGAATCATCGGTTGTATCATTGGT -CTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCA -TTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGC -TAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGAT -CAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAA -TGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAG -TTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAAC -ATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAA -GGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATC -GTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTTGTC -TGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGCGATCAGATATT -TGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATC -AAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTT -GATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTA -CAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAG -CATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAA -TACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTT -TATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAA -TAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTC -CACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGG -AAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGA -TAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAA -AATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAG -TAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAA -CAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAA -CTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATAC -AACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAA -GATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAACTAATTT -CACAGTAGATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTT -ATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATG -CCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTC -CAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATC -ATTACATGCTGTATACTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTA -TATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTT -ATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAAT -AATTTCTACTTACTTAATAGATGATGTGGTAACGGGTGTTATTAATGGGGCTGTATATAC -ATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAAC -ATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCC -CAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCA -TCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACAT -ATCAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAAC -GAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATAT -TAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATA -AAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATA -TAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTTTA -TAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATT -CTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCGCACTC -ATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTAT -CATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTC -ATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTAT -ACATTCTTCTGTTAATTTTACTAGATCATCATGGGTCATAGAATTTATAGGTTCCGTAGT -CCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAAC -TGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGA -TACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTC -TAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGTCAGAATCACATAC -CGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAAT -AATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGT -GAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTT -TATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAG -TTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGC -ATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATT -ACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATC -CGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGA -AATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGC -TTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATAT -TTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACG -CTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAA -TTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTG -ACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAAT -TTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATT -CCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTC -TTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTG -ATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCG -TGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACT -TATTCTCTATATCGGTCCACGTGTATTGCTATAATAGGATACGATTCTATTATATGGTAT -AAAGATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATA -GCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTA -TGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGT -TGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACACCAAAAAAGAAAAA -AGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGT -GGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTA -ATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGA -TACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCC -GTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTG -CATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTA -TTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCA -TCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAA -ACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCG -CAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTA -CATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTT -GCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGG -GTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCA -TAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCAT -AAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCA -TGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCT -GTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCA -CTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAA -AGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTG -GATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTT -TTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTG -CCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAG -ACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTT -TAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAG -ATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTG -TAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTA -TTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTA -TTTCTTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGAT -ATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAAAT -AAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGAC -AAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGG -GTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTAC -TTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACT -ATATCCGGCAATATTTATTCGGCATTGATGACACTAGATGATTTGGTTATTAAACAGTAT -GGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTT -GACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTA -TCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTA -GCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTA -TGTAAGTATCTACGCGGACACACCGATAGCATAGAGGATGAATTTGATCATTTTGAAGAC -GATGATTCGTCTACATGTTCTGCCGTAACCGACAGGGAAACGGATGTATAATTTTTTTTA -TAGTGTGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGA -TGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATT -CAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCA -GATACTGGTTTGATAAACTTTTTATTCCACATGAGTATGTTTGACTTATGGTTAGACACG -CATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGT -TCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAAC -AAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGA -GATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACA -TGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGG -ATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTT -TTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTA -TTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTC -GTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTG -CCCGATCCTCTCTTAAATGAATCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCC -TTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCG -GATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGT -TTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAA -CAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACT -TTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAA -CCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTT -TTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTG -GAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTG -GATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAA -ACGTCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATA -AAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAG -ATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGAC -CAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTA -CAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATA -CGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGA -AACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAAC -TTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATC -TATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAAC -AAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTA -AAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAG -AATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGA -TCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCT -CTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAA -TCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATT -AAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATA -AAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATAC -GGATATATAGGAGACACTATTAGGACATTCTTCAAAGAGAACACGGAAATCCGTCCACGA -GATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTA -ACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAAT -GATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGG -TACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTG -AAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATG -ACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAA -TTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAA -AAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTG -GATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGAT -TCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATA -CACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTGTTTGACTGTTTATAC -TTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGAT -GTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAG -TCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTA -AAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGAC -TATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTAT -GGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAA -TCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTT -TTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGG -TTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAG -ATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATA -TCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACT -CATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAA -TAAAATAACACTATTTTAGTTGGTGGTCGCCATGGATGGTGTTATCGTATACTGTCTAAA -TGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACC -ATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAA -CAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATC -AATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGA -CGATGACAAGACTCCTACCGGTGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGT -TATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGC -GTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTT -TTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGC -ACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGTCTACA -TGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTG -TTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAAC -TCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATG -CTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATC -GTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATC -TAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAA -TTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGG -TATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTAT -TTCATACTATTTTGTGTGATCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTG -ATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCA -AAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGAT -AGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGAC -TCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGA -ACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATAT -AAAGGTACAAAAACAGGATATCGTCAAACTTACTGTATACGATTGCATATATCTATGATA -GGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAA -TATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCT -ATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCA -AAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACA -TTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTA -GAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATA -TACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGAT -GGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGAT -ATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATAT -ACCTACTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCT -TGATAAGAGGCATAATCAATGTTGTAATCCGGTGTCCACCTGGAGAATTTGCCAAGGTCA -GATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCG -CAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTG -ATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGC -TACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCA -TGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGT -GAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCT -ATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCGCTACTT -GGTTAGTGTGTATTATTCAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATC -TTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGAT -AAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAA -AAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTG -TTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGA -AAGGATAAACGCTCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGT -TTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATC -AAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACGATA -ACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGCCATTACTGAG -TGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATAC -GCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAAT -ATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAA -ATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATT -AAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATC -ATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTA -CGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCA -TATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTG -CTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTC -GCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTAT -AGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCA -GAGCTAAAAATATCCTCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTG -TATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCC -ATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTT -GCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATGTA -CCGACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAA -AAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTGGAGGTTACA -ACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATG -ATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAG -TGTATAATAAATTATATGTAGGAGGAGGAATATCTGATGATGTTCAAACTAATACATCTG -AAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATA -ATTATATAATGTATAAATGCGAACCGGTTAAACATAGATATCCATTGGAAAAAACACAGT -ACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATAC -ATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTG -TTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGAT -GATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGG -TATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGAT -AATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATC -ACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACA -TCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTA -AATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCGGAAACTATT -TCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCGCGACT -CCGGAACCAATTACTGATAATGTAGAAGACCATACAGACACCGTCACATACACTAGTGAT -AGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGACTCCGGAACCA -ATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGT -ACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACA -TACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGC -AATTATAAAACCAAGGACTTTGTAGAAATATTTGGTATTACCACATTAATTATATTGTCG -GCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAA -ACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCA -TATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACT -ATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAAC -GAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGG -AAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGT -AAATACAGCGGCTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAG -AAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAA -ATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGC -GTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTAT -TATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGAC -CGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAA -TTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATA -TTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACAT -TATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACC -ATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGT -AAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGT -ACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCT -TATCACGTGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGT -AATTAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACC -AGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGA -GCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAA -GAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACA -TGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTAT -AGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTG -TATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTC -TGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGAC -CAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGAC -ATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGTA -AAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGCGAGTAC -AATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCAT -GCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCA -GTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTG -AACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAGTGCAATGAATATCTACAAATT -GGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAA -AACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTA -GGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAG -TATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATC -GATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGA -AAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTA -AAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTC -CTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTGGATTATGTA -CTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAAT -GTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATG -CTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGAC -TCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGA -CCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGA -TTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCTGGTGAATCAGTCAAATTTGGT -AATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGG -CAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATT -GGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCACGACTACCTCAAA -CTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAG -AAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAG -ACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCG -GATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGAT -GAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAA -CAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAA -CTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTAT -TGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAA -TATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTT -CTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATA -CAGGAATATAATCTTGTTCGAAAATACGAGAAAGTGGATAAAACAATAGTTGATTTTTTA -TCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTAT -TTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATT -AATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAA -TATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAA -AATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATA -AGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTA -TTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATT -AAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCG -TTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAG -AATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGT -CGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGT -AATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAA -CTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTA -ATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATT -AACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTAT -AATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGA -TGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTG -TCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAA -CAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTAT -GATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTT -GATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTT -TTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAA -TGTAATATTCTCGACGTATACGGAAGTCGTGTACGTAATATCATAGCATCTATTAGATAT -CGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGT -TTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACA -TATCTAAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACT -ACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAA -AATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAAC -ATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGA -TAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGT -CTGCGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGA -TTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAG -TTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAA -TGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTG -TCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGG -ATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCC -ATCATGTCAACAAAAATGTGATATACCGTCTCTATCTAATGGATTAATTTCCGGATCTAC -ATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTC -TCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATC -TAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACT -CTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATAT -AATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGT -TTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATA -AATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAG -AATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTA -GAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACA -CCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATA -TAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATG -GTATAATGATGAATGAATGCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAA -TGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATG -ATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACG -ACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAA -CTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAG -TTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAA -AACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACA -CTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATT -CATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTA -TTACAGAGTCATGCGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATA -AAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTA -GAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGG -GTGATGAACGACAATATTCTATTACTGCAGAGGGAAAATGCTATAAAGGAATAAAATATG -AAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTA -CTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAA -AATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGAT -ATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATA -AGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATA -TATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAG -GAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTG -AACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTG -GACCACCAACTGTAAGATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATC -CGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATA -TCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATG -ATATCGATGACTACGATTGCACGTCTACAGGTTGCAGCATAGACTTTGCCACAACAGAAA -AAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGA -GTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAG -AAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAAC -AGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTC -TTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAA -ACTGCATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCT -GATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCCATGTCTATTAGACGATGCGAGAA -GACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTA -TCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGA -AGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTAT -CACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACAT -GAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTCTATTTCTGTATA -TTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATAT -CAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTT -CATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGTGTCAGAATTGA -TACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGT -CTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGAT -ATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAA -AATGATATGATAGTTCTTACAAGTAGAGATTGAGTTTTAAATGGATTCTATTAATTACCG -GGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCC -GATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGAT -GCGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGA -TGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATG -TCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTA -ATATTAATACATTATCGTATATCTACAACGATGTAAGAAACTTCATATTGGATAATATTA -CTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTA -CTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTA -TATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTT -TTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGGTGTATGGAAGTTAGTAC -ATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGG -TATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATACAGATACAGATACAGATAC -AGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGA -TAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAA -GAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGA -TTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATC -TACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGCATG -GAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTA -TATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAAT -TACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTAT -ATATCTGTATTGGATCCTTTGACTATCGACAACTGGACACGGGAACGTGGTATAAAGTAT -TTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCGTTATA -AAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTC -ACTATGATAAACACGTTAGAGTTTATACACTCTCGAGGATTTACTCATGGAAAAATAGAA -CCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAAC -AAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAAT -ATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTA -GAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAA -AGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTT -GAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTA -TACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAA -GATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATAT -TAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCA -GGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGT -CAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAAT -ATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCA -TGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTG -GCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGT -GTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTG -ATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCG -AAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAA -GTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTA -ACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAA -ACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAAT -GGTGTAACTCTCTGGAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAG -GTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAA -CTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAA -CGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGG -CAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGA -TTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATT -AAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATT -TTTTTTAAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCA -ATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAGCACTGTGGATGT -GACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCG -TCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGGCACACTCCTCTCTTTT -AAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGG -GATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACC -ATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGT -GAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAAT -TACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTC -TTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAA -TAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCA -GACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTT -AGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAA -TATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGA -TAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATG -CATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGT -CTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGG -TGAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACGCAGAATTATA -TGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATT -ACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATA -TATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCA -GAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAG -GAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGCAGAGTATCGTTGAGACTTC -CCACAACGGACGCCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGA -CGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACTGATAAGAGACG -TGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTAC -GTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATG -TATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCA -ACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATGCATATTATTAA -TCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAA -TTGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTA -GATAATATACTGTCTCCGTATTTTTAAAAAATTGCCACATCCTTTATTAAATCATGAATG -GGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAG -GGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTT -ATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGCATAAACTTTC -TAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAG -ATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGA -ATTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATA -CTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGAT -CTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGT -GTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATG -AAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCC -ATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCT -AAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCC -GCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCAT -AGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTT -TCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGT -AACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTT -AGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTAT -GATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAAACATTATAATAATATA -ACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGA -AAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTT -CATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACG -GTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACG -ATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGAT -GTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATAC -TCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACT -GAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACT -CTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAAT -TATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTA -GGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTA -AAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTT -ATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATT -ATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTG -GTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATATGAGAATGAATATGAAT -TCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAA -CCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATG -ATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGC -GGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATA -ATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATG -TAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAA -AGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATT -CTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAATGTGGTAA -AAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAA -TTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAAC -ATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATT -TCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATT -ATAATATAAGCGACAGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAA -TAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAG -GTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATA -ATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAG -GAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACT -CAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTA -ATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAA -GTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTGGATGGGTACGATA -TTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTC -AGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTA -AAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGA -TTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATG -TTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGT -TACTGGACCCATCCTTTTATTATAGATTCAGAAATGCTATCGAAAACAAATTAGACCAAT -ACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAG -TCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCA -CTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTC -GTGCAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCG -AAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATA -TGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCG -AAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAG -AGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAA -TAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGAT -TATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACG -TAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCG -GAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGCTGCCGGATCTACGTATTTTAAAA -CAATGTTCACAACACCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATCTACAGATGT -TCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTA -TGAATGTGATAGACGTATTAAAATGCACCGACTAAGAACGTAGAACGAACTATAGAATGT -TATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGT -TATGGCATGTGTGTATTAGATCAATACATATACATTATAGGCGGTCGTACCCAACACTGA -TTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAA -TAAAGTTATGAGATACGCACTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACT -GGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAA -GATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATAACGGATGGG -AATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATA -CCATAATGATGTTACATTGTTATGAAACGTATATGTTACAAGATACATTTAATGTGCTTA -CGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTAT -GTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCAAGTATGAATACGGAGTA -CAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATAC -ATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATA -TACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATT -ATATATATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAA -GAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCT -ACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATAT -ATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGAC -GTAGATATTCCGTATTGTGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGT -ATCGAGTTCCATGCCTCCTTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTT -AATAATGCTAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGT -AAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGACAGTTATTAGC -GCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGAC -AAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAAT -GACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCA -TACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAAC -ATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAA -AGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTA -CCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAG -ATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAAT -GAGGAGTATACAGAAGCATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTA -TATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGA -CATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTAT -CACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATA -CATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAA -AATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGC -GTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCC -CATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGA -CCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTG -GACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTA -TTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCA -AAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTAC -TTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTA -TCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGG -AGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGT -CGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAA -AAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAG -ATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACT -ATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCC -ACAATTATTGACGGGCTTGTTTGTGACCGGCAATCATGAATTTACAGAAATTATCTCTGG -CTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGT -TGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTAC -CGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTA -ATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACG -GAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAAC -TACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATT -ATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAA -CTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTA -TATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATC -TTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTG -ACAATAACACATTGCATGGTAATATAGGATTTTTGGAAATAAATAATTGTTACAATGTTT -CTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGC -TAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAAT -GTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGA -ATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAG -TTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGG -TATATAACTATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATT -TAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACGCAATAGTGTTTCGACAA -CTAACAGCAGAAAAAGACGAGATCTGAATGGTGAGTTTGAATTTTCCACTTCCAAGGAAT -TAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCAC -CTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACG -CGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAG -GTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAAT -CGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAG -CTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTC -CGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAA -CTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTG -TTATTTACAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGG -ATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACAC -AGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGAC -AAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTAT -ATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAAC -AATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCA -CCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTC -CAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTAC -ACAGACCTCCGCCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGAC -CAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTG -TATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAA -AACCAAACGATGATACCTATTCACTTCTTCAACGGCCAAAAATTGAACCAGAATATGCGG -AGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAA -AATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAG -CAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGA -GTAGAAAAGATCAGATGAGCAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTAT -CAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTG -CAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACA -TGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACGCTG -GCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACA -CACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGG -CTTTGTATTTCTTAGATGTTATCGACTCAGAGATCCTATATCTAAACACATCAAATTTAG -TTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGG -ACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTA -TCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAG -CAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGG -CGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATC -CTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTA -TTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACA -GATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTA -GCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCT -TTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATG -TATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTG -AAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAAC -ATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAG -CCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATG -ATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCAT -TTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTACCACATTGGCTA -GAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATG -CAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAA -TGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGA -CCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATG -ACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGA -CGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATG -GAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTA -CCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATC -TGACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAA -CATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTG -GTTGGTTAAAATCTAGTGGCTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTC -ATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGA -GAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATA -CATGGATAGAATCTAACGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACA -ATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAAT -ACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAA -AGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAG -ATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATA -TTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAAT -CCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCGTGTTAAAAAGTACT -ATTCTATTGATAATTATCTATGTGGTACTTTAGATGATTATATATACACCTCTGTAGAAT -ATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCAT -CAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACG -CCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACA -TGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATC -TAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTAC -TGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGA -AATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTG -AAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAG -AACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTA -AAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGT -ATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTA -TGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATT -GTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGAC -CTCTTGTAATTCGAGTATAGGAAGCAGTATTACCATATCAACTTCCGAGTTAACAATTAC -TCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATTACTATTCAGTCGTTGATAA -ACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACGCA -GTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACC -CACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTC -TCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAAT -GGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAA -CGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAA -TTAATCATTATTGACTTAACGATGACGAAAGTTATCATCATCTTAGGATTCTTGATTATT -AATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATACACAAG -AATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATCATCGATGTGATAAATA -CAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTC -TCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATCTGTC -ATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTG -CTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACC -ATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGT -AAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCG -TAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTT -ATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATG -GTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGT -GGCGTCTGCCAGCGTGCACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTC -TACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGAC -ATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGAT -TTTCGCATTGACTTTACACAGACATAAACATCCCCTGAATCTGTACCTACTTTGTGGATT -TACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCGCGTATCGT -TATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACA -ATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAAT -TTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCAT -TTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTC -ACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATT -AAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTAA -CCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCAC -GCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATC -CTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTC -ATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGGAT -TCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAAT -GACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCT -ATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAG -ATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAA -ATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGAT -GAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAAT -AGCTATGGATATCTCGTTAAGAATATTCTCGATAAGAGACATAATGTAGACATAGTTATT -ATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAA -GATGATATCATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGT -AATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTG -AATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATC -GTTAAAAATCTGTAAGAGGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGG -ATATATAGATAACACAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACG -TACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCA -TGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGA -ATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTA -ATAGACCTATGAAATTAAAAAAGTTAACAATGGATTCGCGTATAGCTATTTACGTATTAG -TATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGA -AAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTA -TGACCTTTGATGGAAAGGATATTTATCCATCTATCGCGTTCATGGTCGGTAATAAACTTT -TCCTAGATCTTTATAAAAATATCTTTGTAGAATTTTTCAGACTATTTCGAGTATCTGTAA -GTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTA -CAATTAAACAACATTACTTTTATAACGGCGAAGAATATACTGAAATTGATAGATCGAAAA -AAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCG -ATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACA -AAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGA -GAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAG -TGCGATTCGCGCCATGGAGTCGGCAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGA -CCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGA -CTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACC -AATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGA -TCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATT -AGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGT -ACAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATTT -TATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGG -AATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGA -AAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGA -TGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCA -ACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTT -AGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATAC -ATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAA -AATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACT -TAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGT -AGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAA -ACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAAT -CTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCC -AGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGT -CACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGA -TGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGT -CATATAGAGTTCTCTCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAA -GTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTTATAAGTTAG -TTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTTATAAGTTAGTTTATAGTCTAA -CACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGA -AGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTA -ACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATA -TGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAAC -ACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGA -ATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTG -ATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAA -TCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCG -ATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGT -ACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTC -TTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGA -GTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAA -ACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATA -CCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATAC -GTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTC -ATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAG -AAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTC -TCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATA -CAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCG -TATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGG -TGTTTGAAAACAGAAACATCATATACAAGGCGGATGTCGTTAATGACATCATCCACCACA -GACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTC -CCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCAT -TTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAA -ATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCC -TCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCC -GGTATCACACCTATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACG -ACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAG -CACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGG -AAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACG -GAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATA -TGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCAT -GAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGA -TATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAA -TCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGAC -TAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACA -GGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAA -CACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGATC -ATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGG -ATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACAC -CGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGA -TGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGG -TCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGA -TCCCGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTT -TACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAA -ATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCAT -GCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACAT -ACTATATAGTAATACCAATACTCAAGACTACGAAACGGATACAATCTCTTATCATATGGG -TAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCAC -TAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCCATAAATAATAAATACAA -TAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAG -AATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATG -CATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCCTCATCCTCGTGTAC -TGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGA -CCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGA -TGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGG -TGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGA -ATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCAGGACAAGGTAA -GGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTC -TATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGCGACATCAAGACCCATCCAGTACT -TGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGT -TGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGA -ATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGG -TGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGA -TAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACC -ACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATGTTTAACTACA -TTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGA -TCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAAAAATAT -TTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCT -CAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCT -TATGCCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTT -AACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATC -CATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATA -CAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATA -TCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTC -TGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTA -AACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTAC -GGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAAT diff --git a/data/nextstrain/mpx/mpxv/ancestral/tree.json b/data/nextstrain/mpx/mpxv/ancestral/tree.json deleted file mode 100644 index 0fdb7fcb..00000000 --- a/data/nextstrain/mpx/mpxv/ancestral/tree.json +++ /dev/null @@ -1,142361 +0,0 @@ -{ - "version": "v2", - "meta": { - "title": "Nextclade reference tree for MPXV (reconstructed ancestral reference seq in NC_063383.1 coordinates)", - "updated": "2023-07-31", - "build_url": "https://github.com/nextstrain/monkeypox", - "data_provenance": [ - { - "name": "GenBank", - "url": "https://www.ncbi.nlm.nih.gov/genbank/" - } - ], - "maintainers": [ - { - "name": "Nextstrain team", - "url": "http://nextstrain.org" - } - ], - "display_defaults": { - "color_by": "clade_membership", - "map_triplicate": false, - "distance_measure": "div", - "transmission_lines": false - }, - "genome_annotations": { - "nuc": { - "end": 197209, - "start": 1, - "strand": "+", - "seqid": "config/genemap.gff", - "type": "source" - }, - "NBT03_gp052": { - "end": 55141, - "seqid": "config/genemap.gff", - "start": 54752, - "strand": "+", - "type": "gene" - }, - "NBT03_gp174": { - "end": 190940, - "seqid": "config/genemap.gff", - "start": 190410, - "strand": "+", - "type": "gene" - }, - "NBT03_gp175": { - "end": 192367, - "seqid": "config/genemap.gff", - "start": 191054, - "strand": "+", - "type": "gene" - }, - "OPG001": { - "end": 196375, - "seqid": "config/genemap.gff", - "start": 195635, - "strand": "+", - "type": "gene" - }, - "OPG002": { - "end": 195508, - "seqid": "config/genemap.gff", - "start": 194459, - "strand": "+", - "type": "gene" - }, - "OPG003": { - "end": 194369, - "seqid": "config/genemap.gff", - "start": 192603, - "strand": "+", - "type": "gene" - }, - "OPG005": { - "end": 189660, - "seqid": "config/genemap.gff", - "start": 189199, - "strand": "+", - "type": "gene" - }, - "OPG015": { - "end": 6156, - "seqid": "config/genemap.gff", - "start": 4843, - "strand": "+", - "type": "gene" - }, - "OPG019": { - "end": 8008, - "seqid": "config/genemap.gff", - "start": 7580, - "strand": "+", - "type": "gene" - }, - "OPG021": { - "end": 10315, - "seqid": "config/genemap.gff", - "start": 9587, - "strand": "+", - "type": "gene" - }, - "OPG022": { - "end": 10858, - "seqid": "config/genemap.gff", - "start": 10478, - "strand": "+", - "type": "gene" - }, - "OPG023": { - "end": 12900, - "seqid": "config/genemap.gff", - "start": 10918, - "strand": "+", - "type": "gene" - }, - "OPG024": { - "end": 13228, - "seqid": "config/genemap.gff", - "start": 13034, - "strand": "+", - "type": "gene" - }, - "OPG025": { - "end": 15267, - "seqid": "config/genemap.gff", - "start": 13375, - "strand": "+", - "type": "gene" - }, - "OPG027": { - "end": 16377, - "seqid": "config/genemap.gff", - "start": 15925, - "strand": "+", - "type": "gene" - }, - "OPG029": { - "end": 17069, - "seqid": "config/genemap.gff", - "start": 16602, - "strand": "+", - "type": "gene" - }, - "OPG030": { - "end": 17833, - "seqid": "config/genemap.gff", - "start": 17213, - "strand": "+", - "type": "gene" - }, - "OPG031": { - "end": 18828, - "seqid": "config/genemap.gff", - "start": 17878, - "strand": "+", - "type": "gene" - }, - "OPG034": { - "end": 20005, - "seqid": "config/genemap.gff", - "start": 19361, - "strand": "+", - "type": "gene" - }, - "OPG035": { - "end": 20404, - "seqid": "config/genemap.gff", - "start": 20051, - "strand": "+", - "type": "gene" - }, - "OPG036": { - "end": 21064, - "seqid": "config/genemap.gff", - "start": 20531, - "strand": "+", - "type": "gene" - }, - "OPG037": { - "end": 22433, - "seqid": "config/genemap.gff", - "start": 21105, - "strand": "+", - "type": "gene" - }, - "OPG038": { - "end": 23159, - "seqid": "config/genemap.gff", - "start": 22497, - "strand": "+", - "type": "gene" - }, - "OPG039": { - "end": 24118, - "seqid": "config/genemap.gff", - "start": 23264, - "strand": "+", - "type": "gene" - }, - "OPG040": { - "end": 25478, - "seqid": "config/genemap.gff", - "start": 24351, - "strand": "+", - "type": "gene" - }, - "OPG042": { - "end": 27097, - "seqid": "config/genemap.gff", - "start": 25823, - "strand": "+", - "type": "gene" - }, - "OPG043": { - "end": 27955, - "seqid": "config/genemap.gff", - "start": 27125, - "strand": "+", - "type": "gene" - }, - "OPG044": { - "end": 28540, - "seqid": "config/genemap.gff", - "start": 28091, - "strand": "+", - "type": "gene" - }, - "OPG045": { - "end": 29262, - "seqid": "config/genemap.gff", - "start": 28603, - "strand": "+", - "type": "gene" - }, - "OPG046": { - "end": 29729, - "seqid": "config/genemap.gff", - "start": 29274, - "strand": "+", - "type": "gene" - }, - "OPG047": { - "end": 31194, - "seqid": "config/genemap.gff", - "start": 29746, - "strand": "+", - "type": "gene" - }, - "OPG048": { - "end": 32164, - "seqid": "config/genemap.gff", - "start": 31205, - "strand": "+", - "type": "gene" - }, - "OPG049": { - "end": 33151, - "seqid": "config/genemap.gff", - "start": 32195, - "strand": "+", - "type": "gene" - }, - "OPG050": { - "end": 33408, - "seqid": "config/genemap.gff", - "start": 33181, - "strand": "+", - "type": "gene" - }, - "OPG051": { - "end": 33649, - "seqid": "config/genemap.gff", - "start": 33425, - "strand": "+", - "type": "gene" - }, - "OPG052": { - "end": 33995, - "seqid": "config/genemap.gff", - "start": 33801, - "strand": "+", - "type": "gene" - }, - "OPG053": { - "end": 34690, - "seqid": "config/genemap.gff", - "start": 34052, - "strand": "+", - "type": "gene" - }, - "OPG054": { - "end": 35996, - "seqid": "config/genemap.gff", - "start": 34677, - "strand": "+", - "type": "gene" - }, - "OPG055": { - "end": 37083, - "seqid": "config/genemap.gff", - "start": 36019, - "strand": "+", - "type": "gene" - }, - "OPG056": { - "end": 39034, - "seqid": "config/genemap.gff", - "start": 37127, - "strand": "+", - "type": "gene" - }, - "OPG057": { - "end": 40195, - "seqid": "config/genemap.gff", - "start": 39077, - "strand": "+", - "type": "gene" - }, - "OPG058": { - "end": 40434, - "seqid": "config/genemap.gff", - "start": 40213, - "strand": "+", - "type": "gene" - }, - "OPG059": { - "end": 40633, - "seqid": "config/genemap.gff", - "start": 40484, - "strand": "+", - "type": "gene" - }, - "OPG060": { - "end": 41182, - "seqid": "config/genemap.gff", - "start": 40706, - "strand": "+", - "type": "gene" - }, - "OPG061": { - "end": 41884, - "seqid": "config/genemap.gff", - "start": 41189, - "strand": "+", - "type": "gene" - }, - "OPG062": { - "end": 42252, - "seqid": "config/genemap.gff", - "start": 41947, - "strand": "+", - "type": "gene" - }, - "OPG063": { - "end": 43688, - "seqid": "config/genemap.gff", - "start": 42249, - "strand": "+", - "type": "gene" - }, - "OPG064": { - "end": 45898, - "seqid": "config/genemap.gff", - "start": 43685, - "strand": "+", - "type": "gene" - }, - "OPG065": { - "end": 46483, - "seqid": "config/genemap.gff", - "start": 46022, - "strand": "+", - "type": "gene" - }, - "OPG066": { - "end": 47428, - "seqid": "config/genemap.gff", - "start": 46649, - "strand": "+", - "type": "gene" - }, - "OPG068": { - "end": 49904, - "seqid": "config/genemap.gff", - "start": 48201, - "strand": "+", - "type": "gene" - }, - "OPG069": { - "end": 50486, - "seqid": "config/genemap.gff", - "start": 49986, - "strand": "+", - "type": "gene" - }, - "OPG070": { - "end": 51411, - "seqid": "config/genemap.gff", - "start": 50590, - "strand": "+", - "type": "gene" - }, - "OPG071": { - "end": 54438, - "seqid": "config/genemap.gff", - "start": 51418, - "strand": "+", - "type": "gene" - }, - "OPG072": { - "end": 54757, - "seqid": "config/genemap.gff", - "start": 54470, - "strand": "+", - "type": "gene" - }, - "OPG074": { - "end": 57125, - "seqid": "config/genemap.gff", - "start": 55128, - "strand": "+", - "type": "gene" - }, - "OPG075": { - "end": 57498, - "seqid": "config/genemap.gff", - "start": 57172, - "strand": "+", - "type": "gene" - }, - "OPG076": { - "end": 57630, - "seqid": "config/genemap.gff", - "start": 57523, - "strand": "+", - "type": "gene" - }, - "OPG077": { - "end": 58583, - "seqid": "config/genemap.gff", - "start": 57645, - "strand": "+", - "type": "gene" - }, - "OPG078": { - "end": 58811, - "seqid": "config/genemap.gff", - "start": 58590, - "strand": "+", - "type": "gene" - }, - "OPG079": { - "end": 59621, - "seqid": "config/genemap.gff", - "start": 58812, - "strand": "+", - "type": "gene" - }, - "OPG080": { - "end": 62018, - "seqid": "config/genemap.gff", - "start": 59703, - "strand": "+", - "type": "gene" - }, - "OPG081": { - "end": 62285, - "seqid": "config/genemap.gff", - "start": 62046, - "strand": "+", - "type": "gene" - }, - "OPG082": { - "end": 63452, - "seqid": "config/genemap.gff", - "start": 62304, - "strand": "+", - "type": "gene" - }, - "OPG083": { - "end": 64716, - "seqid": "config/genemap.gff", - "start": 63445, - "strand": "+", - "type": "gene" - }, - "OPG084": { - "end": 66752, - "seqid": "config/genemap.gff", - "start": 64722, - "strand": "+", - "type": "gene" - }, - "OPG085": { - "end": 68531, - "seqid": "config/genemap.gff", - "start": 66756, - "strand": "+", - "type": "gene" - }, - "OPG086": { - "end": 68863, - "seqid": "config/genemap.gff", - "start": 68528, - "strand": "+", - "type": "gene" - }, - "OPG087": { - "end": 69519, - "seqid": "config/genemap.gff", - "start": 68857, - "strand": "+", - "type": "gene" - }, - "OPG088": { - "end": 69863, - "seqid": "config/genemap.gff", - "start": 69489, - "strand": "+", - "type": "gene" - }, - "OPG089": { - "end": 71170, - "seqid": "config/genemap.gff", - "start": 69866, - "strand": "+", - "type": "gene" - }, - "OPG090": { - "end": 71370, - "seqid": "config/genemap.gff", - "start": 71179, - "strand": "+", - "type": "gene" - }, - "OPG091": { - "end": 71867, - "seqid": "config/genemap.gff", - "start": 71370, - "strand": "+", - "type": "gene" - }, - "OPG092": { - "end": 72947, - "seqid": "config/genemap.gff", - "start": 71832, - "strand": "+", - "type": "gene" - }, - "OPG093": { - "end": 73760, - "seqid": "config/genemap.gff", - "start": 72978, - "strand": "+", - "type": "gene" - }, - "OPG094": { - "end": 74802, - "seqid": "config/genemap.gff", - "start": 73780, - "strand": "+", - "type": "gene" - }, - "OPG095": { - "end": 75555, - "seqid": "config/genemap.gff", - "start": 74803, - "strand": "+", - "type": "gene" - }, - "OPG096": { - "end": 75865, - "seqid": "config/genemap.gff", - "start": 75587, - "strand": "+", - "type": "gene" - }, - "OPG097": { - "end": 76875, - "seqid": "config/genemap.gff", - "start": 75841, - "strand": "+", - "type": "gene" - }, - "OPG098": { - "end": 77655, - "seqid": "config/genemap.gff", - "start": 76900, - "strand": "+", - "type": "gene" - }, - "OPG099": { - "end": 78051, - "seqid": "config/genemap.gff", - "start": 77665, - "strand": "+", - "type": "gene" - }, - "OPG100": { - "end": 78466, - "seqid": "config/genemap.gff", - "start": 78008, - "strand": "+", - "type": "gene" - }, - "OPG101": { - "end": 79019, - "seqid": "config/genemap.gff", - "start": 78486, - "strand": "+", - "type": "gene" - }, - "OPG102": { - "end": 80086, - "seqid": "config/genemap.gff", - "start": 79085, - "strand": "+", - "type": "gene" - }, - "OPG103": { - "end": 80558, - "seqid": "config/genemap.gff", - "start": 80001, - "strand": "+", - "type": "gene" - }, - "OPG104": { - "end": 81019, - "seqid": "config/genemap.gff", - "start": 80618, - "strand": "+", - "type": "gene" - }, - "OPG105": { - "end": 84986, - "seqid": "config/genemap.gff", - "start": 81126, - "strand": "+", - "type": "gene" - }, - "OPG106": { - "end": 85498, - "seqid": "config/genemap.gff", - "start": 84983, - "strand": "+", - "type": "gene" - }, - "OPG107": { - "end": 86081, - "seqid": "config/genemap.gff", - "start": 85512, - "strand": "+", - "type": "gene" - }, - "OPG108": { - "end": 87059, - "seqid": "config/genemap.gff", - "start": 86085, - "strand": "+", - "type": "gene" - }, - "OPG109": { - "end": 89447, - "seqid": "config/genemap.gff", - "start": 87060, - "strand": "+", - "type": "gene" - }, - "OPG110": { - "end": 90264, - "seqid": "config/genemap.gff", - "start": 89632, - "strand": "+", - "type": "gene" - }, - "OPG111": { - "end": 91209, - "seqid": "config/genemap.gff", - "start": 90265, - "strand": "+", - "type": "gene" - }, - "OPG112": { - "end": 91687, - "seqid": "config/genemap.gff", - "start": 91247, - "strand": "+", - "type": "gene" - }, - "OPG113": { - "end": 94268, - "seqid": "config/genemap.gff", - "start": 91731, - "strand": "+", - "type": "gene" - }, - "OPG114": { - "end": 94667, - "seqid": "config/genemap.gff", - "start": 94227, - "strand": "+", - "type": "gene" - }, - "OPG115": { - "end": 95361, - "seqid": "config/genemap.gff", - "start": 94660, - "strand": "+", - "type": "gene" - }, - "OPG116": { - "end": 96017, - "seqid": "config/genemap.gff", - "start": 95361, - "strand": "+", - "type": "gene" - }, - "OPG117": { - "end": 98406, - "seqid": "config/genemap.gff", - "start": 96049, - "strand": "+", - "type": "gene" - }, - "OPG118": { - "end": 100359, - "seqid": "config/genemap.gff", - "start": 98446, - "strand": "+", - "type": "gene" - }, - "OPG119": { - "end": 100871, - "seqid": "config/genemap.gff", - "start": 100386, - "strand": "+", - "type": "gene" - }, - "OPG120": { - "end": 101748, - "seqid": "config/genemap.gff", - "start": 100834, - "strand": "+", - "type": "gene" - }, - "OPG121": { - "end": 102431, - "seqid": "config/genemap.gff", - "start": 101790, - "strand": "+", - "type": "gene" - }, - "OPG122": { - "end": 103174, - "seqid": "config/genemap.gff", - "start": 102428, - "strand": "+", - "type": "gene" - }, - "OPG123": { - "end": 105070, - "seqid": "config/genemap.gff", - "start": 103175, - "strand": "+", - "type": "gene" - }, - "OPG124": { - "end": 105968, - "seqid": "config/genemap.gff", - "start": 105105, - "strand": "+", - "type": "gene" - }, - "OPG125": { - "end": 107654, - "seqid": "config/genemap.gff", - "start": 105999, - "strand": "+", - "type": "gene" - }, - "OPG126": { - "end": 108130, - "seqid": "config/genemap.gff", - "start": 107678, - "strand": "+", - "type": "gene" - }, - "OPG127": { - "end": 108825, - "seqid": "config/genemap.gff", - "start": 108151, - "strand": "+", - "type": "gene" - }, - "OPG128": { - "end": 109055, - "seqid": "config/genemap.gff", - "start": 108822, - "strand": "+", - "type": "gene" - }, - "OPG129": { - "end": 111004, - "seqid": "config/genemap.gff", - "start": 109070, - "strand": "+", - "type": "gene" - }, - "OPG130": { - "end": 111902, - "seqid": "config/genemap.gff", - "start": 111057, - "strand": "+", - "type": "gene" - }, - "OPG131": { - "end": 112425, - "seqid": "config/genemap.gff", - "start": 111940, - "strand": "+", - "type": "gene" - }, - "OPG132": { - "end": 113540, - "seqid": "config/genemap.gff", - "start": 112422, - "strand": "+", - "type": "gene" - }, - "OPG133": { - "end": 115696, - "seqid": "config/genemap.gff", - "start": 113564, - "strand": "+", - "type": "gene" - }, - "OPG134": { - "end": 116628, - "seqid": "config/genemap.gff", - "start": 115750, - "strand": "+", - "type": "gene" - }, - "OPG135": { - "end": 116911, - "seqid": "config/genemap.gff", - "start": 116609, - "strand": "+", - "type": "gene" - }, - "OPG136": { - "end": 119587, - "seqid": "config/genemap.gff", - "start": 116912, - "strand": "+", - "type": "gene" - }, - "OPG137": { - "end": 120558, - "seqid": "config/genemap.gff", - "start": 119602, - "strand": "+", - "type": "gene" - }, - "OPG138": { - "end": 121132, - "seqid": "config/genemap.gff", - "start": 120560, - "strand": "+", - "type": "gene" - }, - "OPG139": { - "end": 121368, - "seqid": "config/genemap.gff", - "start": 121156, - "strand": "+", - "type": "gene" - }, - "OPG140": { - "end": 121746, - "seqid": "config/genemap.gff", - "start": 121474, - "strand": "+", - "type": "gene" - }, - "OPG141": { - "end": 121924, - "seqid": "config/genemap.gff", - "start": 121763, - "strand": "+", - "type": "gene" - }, - "OPG142": { - "end": 122198, - "seqid": "config/genemap.gff", - "start": 121914, - "strand": "+", - "type": "gene" - }, - "OPG143": { - "end": 123315, - "seqid": "config/genemap.gff", - "start": 122182, - "strand": "+", - "type": "gene" - }, - "OPG144": { - "end": 123932, - "seqid": "config/genemap.gff", - "start": 123318, - "strand": "+", - "type": "gene" - }, - "OPG145": { - "end": 125425, - "seqid": "config/genemap.gff", - "start": 123947, - "strand": "+", - "type": "gene" - }, - "OPG146": { - "end": 125639, - "seqid": "config/genemap.gff", - "start": 125406, - "strand": "+", - "type": "gene" - }, - "OPG147": { - "end": 125987, - "seqid": "config/genemap.gff", - "start": 125640, - "strand": "+", - "type": "gene" - }, - "OPG148": { - "end": 127266, - "seqid": "config/genemap.gff", - "start": 125986, - "strand": "+", - "type": "gene" - }, - "OPG149": { - "end": 127759, - "seqid": "config/genemap.gff", - "start": 127196, - "strand": "+", - "type": "gene" - }, - "OPG150": { - "end": 128927, - "seqid": "config/genemap.gff", - "start": 127779, - "strand": "+", - "type": "gene" - }, - "OPG151": { - "end": 132418, - "seqid": "config/genemap.gff", - "start": 128924, - "strand": "+", - "type": "gene" - }, - "OPG153": { - "end": 137667, - "seqid": "config/genemap.gff", - "start": 136138, - "strand": "+", - "type": "gene" - }, - "OPG154": { - "end": 138050, - "seqid": "config/genemap.gff", - "start": 137718, - "strand": "+", - "type": "gene" - }, - "OPG155": { - "end": 138491, - "seqid": "config/genemap.gff", - "start": 138051, - "strand": "+", - "type": "gene" - }, - "OPG156": { - "end": 139409, - "seqid": "config/genemap.gff", - "start": 138492, - "strand": "+", - "type": "gene" - }, - "OPG157": { - "end": 139608, - "seqid": "config/genemap.gff", - "start": 139372, - "strand": "+", - "type": "gene" - }, - "OPG158": { - "end": 139769, - "seqid": "config/genemap.gff", - "start": 139641, - "strand": "+", - "type": "gene" - }, - "OPG159": { - "end": 140205, - "seqid": "config/genemap.gff", - "start": 139768, - "strand": "+", - "type": "gene" - }, - "OPG160": { - "end": 141074, - "seqid": "config/genemap.gff", - "start": 140172, - "strand": "+", - "type": "gene" - }, - "OPG161": { - "end": 141647, - "seqid": "config/genemap.gff", - "start": 141102, - "strand": "+", - "type": "gene" - }, - "OPG162": { - "end": 142158, - "seqid": "config/genemap.gff", - "start": 141652, - "strand": "+", - "type": "gene" - }, - "OPG163": { - "end": 142732, - "seqid": "config/genemap.gff", - "start": 142202, - "strand": "+", - "type": "gene" - }, - "OPG164": { - "end": 143464, - "seqid": "config/genemap.gff", - "start": 142778, - "strand": "+", - "type": "gene" - }, - "OPG165": { - "end": 144322, - "seqid": "config/genemap.gff", - "start": 143516, - "strand": "+", - "type": "gene" - }, - "OPG167": { - "end": 145407, - "seqid": "config/genemap.gff", - "start": 144574, - "strand": "+", - "type": "gene" - }, - "OPG170": { - "end": 146778, - "seqid": "config/genemap.gff", - "start": 146113, - "strand": "+", - "type": "gene" - }, - "OPG171": { - "end": 147389, - "seqid": "config/genemap.gff", - "start": 146988, - "strand": "+", - "type": "gene" - }, - "OPG172": { - "end": 148017, - "seqid": "config/genemap.gff", - "start": 147427, - "strand": "+", - "type": "gene" - }, - "OPG173": { - "end": 148261, - "seqid": "config/genemap.gff", - "start": 148037, - "strand": "+", - "type": "gene" - }, - "OPG174": { - "end": 149395, - "seqid": "config/genemap.gff", - "start": 148355, - "strand": "+", - "type": "gene" - }, - "OPG175": { - "end": 149819, - "seqid": "config/genemap.gff", - "start": 149442, - "strand": "+", - "type": "gene" - }, - "OPG176": { - "end": 150531, - "seqid": "config/genemap.gff", - "start": 149809, - "strand": "+", - "type": "gene" - }, - "OPG178": { - "end": 152123, - "seqid": "config/genemap.gff", - "start": 151509, - "strand": "+", - "type": "gene" - }, - "OPG180": { - "end": 154371, - "seqid": "config/genemap.gff", - "start": 152692, - "strand": "+", - "type": "gene" - }, - "OPG181": { - "end": 155416, - "seqid": "config/genemap.gff", - "start": 154412, - "strand": "+", - "type": "gene" - }, - "OPG185": { - "end": 159858, - "seqid": "config/genemap.gff", - "start": 158917, - "strand": "+", - "type": "gene" - }, - "OPG187": { - "end": 161533, - "seqid": "config/genemap.gff", - "start": 160622, - "strand": "+", - "type": "gene" - }, - "OPG188": { - "end": 163107, - "seqid": "config/genemap.gff", - "start": 161596, - "strand": "+", - "type": "gene" - }, - "OPG189": { - "end": 165018, - "seqid": "config/genemap.gff", - "start": 163333, - "strand": "+", - "type": "gene" - }, - "OPG190": { - "end": 166075, - "seqid": "config/genemap.gff", - "start": 165122, - "strand": "+", - "type": "gene" - }, - "OPG191": { - "end": 166667, - "seqid": "config/genemap.gff", - "start": 166161, - "strand": "+", - "type": "gene" - }, - "OPG192": { - "end": 167279, - "seqid": "config/genemap.gff", - "start": 166731, - "strand": "+", - "type": "gene" - }, - "OPG193": { - "end": 168137, - "seqid": "config/genemap.gff", - "start": 167334, - "strand": "+", - "type": "gene" - }, - "OPG195": { - "end": 168895, - "seqid": "config/genemap.gff", - "start": 168230, - "strand": "+", - "type": "gene" - }, - "OPG197": { - "end": 169972, - "seqid": "config/genemap.gff", - "start": 169670, - "strand": "+", - "type": "gene" - }, - "OPG198": { - "end": 170886, - "seqid": "config/genemap.gff", - "start": 170038, - "strand": "+", - "type": "gene" - }, - "OPG199": { - "end": 172022, - "seqid": "config/genemap.gff", - "start": 170988, - "strand": "+", - "type": "gene" - }, - "OPG200": { - "end": 172599, - "seqid": "config/genemap.gff", - "start": 172150, - "strand": "+", - "type": "gene" - }, - "OPG204": { - "end": 175587, - "seqid": "config/genemap.gff", - "start": 174532, - "strand": "+", - "type": "gene" - }, - "OPG205": { - "end": 178019, - "seqid": "config/genemap.gff", - "start": 175656, - "strand": "+", - "type": "gene" - }, - "OPG208": { - "end": 180339, - "seqid": "config/genemap.gff", - "start": 179266, - "strand": "+", - "type": "gene" - }, - "OPG209": { - "end": 181090, - "seqid": "config/genemap.gff", - "start": 180518, - "strand": "+", - "type": "gene" - }, - "OPG210": { - "end": 186998, - "seqid": "config/genemap.gff", - "start": 181356, - "strand": "+", - "type": "gene" - } - }, - "colorings": [ - { - "key": "clade_membership", - "title": "Clade", - "type": "categorical", - "scale": [ - [ - "I", - "#4A8CC2" - ], - [ - "II", - "#71B486" - ], - [ - "IIa", - "#ABBD52" - ], - [ - "IIb", - "#DEA73C" - ] - ] - }, - { - "key": "gt", - "title": "Genotype", - "type": "categorical" - }, - { - "key": "outbreak", - "title": "Outbreak", - "type": "categorical", - "scale": [ - [ - "hMPXV-1", - "#4C90C0" - ] - ] - }, - { - "key": "lineage", - "title": "Lineage", - "type": "categorical", - "scale": [ - [ - "A", - "#5E1D9D" - ], - [ - "A.1", - "#4D22AE" - ], - [ - "A.1.1", - "#4531BC" - ], - [ - "B.1", - "#4041C7" - ], - [ - "B.1.1", - "#3F53CD" - ], - [ - "B.1.2", - "#4064CF" - ], - [ - "B.1.3", - "#4375CD" - ], - [ - "C.1", - "#4784C8" - ], - [ - "B.1.4", - "#4C91BF" - ], - [ - "B.1.5", - "#539CB4" - ], - [ - "B.1.6", - "#5AA5A7" - ], - [ - "B.1.7", - "#63AC9A" - ], - [ - "B.1.8", - "#6CB28C" - ], - [ - "B.1.9", - "#77B67E" - ], - [ - "B.1.10", - "#82BA71" - ], - [ - "B.1.11", - "#8FBC66" - ], - [ - "B.1.12", - "#9CBE5B" - ], - [ - "B.1.13", - "#A9BD53" - ], - [ - "B.1.14", - "#B5BD4C" - ], - [ - "B.1.15", - "#C1BA46" - ], - [ - "B.1.16", - "#CDB642" - ], - [ - "B.1.17", - "#D6B03F" - ], - [ - "B.1.18", - "#DEA73B" - ], - [ - "B.1.19", - "#E39B39" - ], - [ - "B.1.20", - "#E68D36" - ], - [ - "A.2", - "#E67C33" - ], - [ - "A.2.1", - "#E5692F" - ], - [ - "A.2.2", - "#E1532B" - ], - [ - "A.2.3", - "#DE3E27" - ], - [ - "A.3", - "#DB2823" - ] - ] - }, - { - "key": "date", - "title": "Collection Date", - "type": "categorical" - }, - { - "key": "host", - "title": "Host", - "type": "categorical" - }, - { - "key": "strain", - "title": "Accession", - "type": "categorical" - }, - { - "key": "strain_original", - "title": "Strain name", - "type": "categorical" - }, - { - "key": "region", - "title": "Region", - "type": "categorical", - "scale": [ - [ - "Asia", - "#447CCD" - ], - [ - "Oceania", - "#5EA9A1" - ], - [ - "Africa", - "#8ABB6A" - ], - [ - "Europe", - "#BEBB48" - ], - [ - "South America", - "#E29E39" - ], - [ - "North America", - "#E2562B" - ] - ] - }, - { - "key": "country", - "title": "Country", - "type": "categorical", - "scale": [ - [ - "Israel", - "#5E1D9D" - ], - [ - "Singapore", - "#4A27B2" - ], - [ - "Vietnam", - "#4530BB" - ], - [ - "Taiwan", - "#3F45C8" - ], - [ - "South Korea", - "#3F51CC" - ], - [ - "Japan", - "#3E5CD0" - ], - [ - "Australia", - "#4067CF" - ], - [ - "Sierra Leone", - "#4272CE" - ], - [ - "Liberia", - "#447DCC" - ], - [ - "Côte d'Ivoire", - "#4785C7" - ], - [ - "Nigeria", - "#4E96BC" - ], - [ - "Gabon", - "#539CB4" - ], - [ - "Cameroon", - "#58A2AC" - ], - [ - "Republic of the Congo", - "#5DA8A3" - ], - [ - "Central African Republic", - "#63AC9A" - ], - [ - "Democratic Republic of the Congo", - "#69B091" - ], - [ - "South Africa", - "#6FB388" - ], - [ - "Portugal", - "#85BA6F" - ], - [ - "Ireland", - "#8DBC68" - ], - [ - "Spain", - "#95BD61" - ], - [ - "United Kingdom", - "#9DBE5A" - ], - [ - "France", - "#A5BE55" - ], - [ - "Belgium", - "#AEBD50" - ], - [ - "Netherlands", - "#B6BD4B" - ], - [ - "Switzerland", - "#BEBB48" - ], - [ - "Germany", - "#CDB642" - ], - [ - "Italy", - "#D3B240" - ], - [ - "Slovenia", - "#D8AE3E" - ], - [ - "Sweden", - "#DDA83C" - ], - [ - "Austria", - "#E1A13A" - ], - [ - "Czech Republic", - "#E49938" - ], - [ - "Slovakia", - "#E69036" - ], - [ - "Finland", - "#E68534" - ], - [ - "Brazil", - "#E56E30" - ], - [ - "Peru", - "#E3602D" - ], - [ - "Colombia", - "#E1522A" - ], - [ - "Mexico", - "#DF4428" - ], - [ - "USA", - "#DD3625" - ], - [ - "Canada", - "#DB2823" - ] - ] - } - ], - "filters": [ - "clade_membership", - "lineage", - "country", - "host", - "institution", - "region" - ], - "panels": [ - "tree", - "entropy" - ], - "extensions": { - "nextclade": { - "clade_node_attrs": [ - { - "name": "outbreak", - "displayName": "Outbreak" - }, - { - "name": "lineage", - "displayName": "Lineage" - } - ] - } - } - }, - "tree": { - "name": "NODE_0000001", - "node_attrs": { - "div": 0, - "clade_membership": { - "value": "outgroup" - } - }, - "branch_attrs": { - "mutations": {}, - "labels": { - "clade": "outgroup" - } - }, - "children": [ - { - "name": "reconstructed_ancestral_mpox", - "node_attrs": { - "div": 0, - "clade_membership": { - "value": "outgroup" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000000", - "node_attrs": { - "div": 0, - "clade_membership": { - "value": "outgroup" - } - }, - "branch_attrs": { - "mutations": {} - }, - "children": [ - { - "name": "NODE_0000002", - "node_attrs": { - "div": 258, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G475A", - "T593-", - "T594-", - "T595-", - "T596-", - "T597-", - "T598-", - "T599-", - "T600-", - "T601-", - "T602-", - "G749A", - "A1309G", - "A2237-", - "C2238-", - "G2239-", - "C2659T", - "C3143T", - "G4042A", - "C4693-", - "T4694-", - "T4695-", - "A4696-", - "A4697-", - "C4698-", - "T4699-", - "A4700-", - "A4701-", - "C4702-", - "T4703-", - "T4704-", - "A4705-", - "T4706-", - "G4707-", - "A4708-", - "C4709-", - "T4710-", - "T4711-", - "A4712-", - "A4713-", - "C4714-", - "T4715-", - "A4716-", - "A4717-", - "C4718-", - "T4719-", - "T4720-", - "A4721-", - "T4722-", - "G4723-", - "A4724-", - "C4725-", - "T4726-", - "T4727-", - "A4728-", - "A4729-", - "C4730-", - "T4731-", - "A4732-", - "A4733-", - "C4734-", - "T4735-", - "T4736-", - "A4737-", - "T4738-", - "G4739-", - "A4740-", - "C4741-", - "T4742-", - "T4743-", - "A4744-", - "A4745-", - "C4746-", - "T4747-", - "A4748-", - "A4749-", - "C4750-", - "T4751-", - "T4752-", - "A4753-", - "T4754-", - "G4755-", - "A4756-", - "C4757-", - "T4758-", - "T4759-", - "A4760-", - "A4761-", - "C4762-", - "T4763-", - "A4764-", - "A4765-", - "C4766-", - "T4767-", - "T4768-", - "A4769-", - "T4770-", - "G4771-", - "A4772-", - "C4773-", - "T4774-", - "T4775-", - "C5809T", - "T6159C", - "T6429-", - "A6430-", - "C7016-", - "T7017-", - "C7018-", - "T7019-", - "C7020-", - "G7021-", - "A7142-", - "T7143-", - "C7144-", - "T7145-", - "G7205A", - "T7404-", - "T7411C", - "A8048-", - "G8277A", - "T8325-", - "T8326-", - "C8414-", - "A8415-", - "T8416-", - "A8417-", - "A8471-", - "T8494-", - "C8603A", - "A8810G", - "A8830G", - "T8913-", - "T8992-", - "G9139A", - "A9282-", - "C9404T", - "A9523-", - "C10242T", - "A11097T", - "C11625T", - "A11991G", - "G12128A", - "C12574A", - "A13276-", - "T13352-", - "C14647T", - "T15281C", - "T15546-", - "A15547-", - "A15657T", - "A15867-", - "C15883A", - "C16002T", - "G16102A", - "T16239C", - "A16608-", - "T16609-", - "C16610-", - "A16611-", - "T16612-", - "C16613-", - "G17525A", - "A18055-", - "C18056-", - "C18057-", - "C18107T", - "G18590A", - "A19086G", - "T19282G", - "C22003T", - "C23283T", - "C23648T", - "A24307-", - "C24336-", - "A25528T", - "G25777A", - "C27692T", - "T28278C", - "A28415G", - "A28583-", - "T28584-", - "T28585-", - "A28586-", - "T28587-", - "C28588-", - "C28589-", - "A28590-", - "G28591-", - "T28592-", - "G28593-", - "T28594-", - "T28595-", - "A28596-", - "A28597-", - "A28598-", - "A28599-", - "A28600-", - "A28601-", - "T29029C", - "C29763T", - "G29923A", - "C30730T", - "C31081T", - "C31529T", - "G31955A", - "G32209-", - "A32210-", - "C32211-", - "C33159T", - "A33193-", - "T33409-", - "C35352A", - "G36445A", - "A39070-", - "G40501A", - "A41207G", - "C41735T", - "A41861G", - "T41929-", - "C44387T", - "G44966A", - "G46303T", - "G46421A", - "C46435T", - "A46506-", - "C46507-", - "A46508-", - "T46583G", - "T46590-", - "G46610A", - "T46643-", - "T46760C", - "A47573-", - "A47700-", - "C47701-", - "G47966A", - "C48041T", - "G48062T", - "T48162-", - "A48163-", - "G48164-", - "C48392T", - "C48951T", - "C49139T", - "G49859T", - "C49957T", - "T50499-", - "C50500-", - "T50575-", - "A50576-", - "C51202T", - "G53269T", - "G54352T", - "G54497A", - "T57433C", - "C57572T", - "G57622A", - "A58872G", - "T59648C", - "G60274T", - "A60457G", - "G60753A", - "G62250A", - "C62649T", - "T66650C", - "G67611A", - "A68297T", - "A68795G", - "C69896T", - "C70774A", - "C71035T", - "A71205G", - "G71553A", - "G71587A", - "A72217T", - "C72231T", - "C73350T", - "T82688C", - "T84290C", - "C84927T", - "A86247G", - "G86728A", - "C87560T", - "T88356A", - "G88746A", - "A89276G", - "C90820T", - "G93339A", - "C94061T", - "G94623A", - "G95280A", - "C97134A", - "G97408A", - "G98202A", - "A98856G", - "G100445A", - "T101536C", - "C101694T", - "C103006A", - "C103764T", - "C103805A", - "C104134T", - "A104556G", - "C104840T", - "G106554A", - "G107118C", - "C107322A", - "G107764A", - "G109874A", - "G111095T", - "A111303G", - "G111715A", - "G112206A", - "A112221G", - "C112455T", - "A113916G", - "G113924A", - "T114770C", - "C115676T", - "A116427C", - "T116735C", - "C117047T", - "G118640A", - "A118740T", - "C118789T", - "C118903T", - "G119474A", - "G123382A", - "A124691G", - "C124714A", - "A125365G", - "G126603A", - "T127137C", - "A128940T", - "A129767G", - "C131809T", - "G132286A", - "T132811-", - "G132887A", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "T133084-", - "T133085-", - "T133086-", - "T133087-", - "T133088-", - "T133089-", - "T133090-", - "T133091-", - "T133092-", - "C133164-", - "A133165-", - "A133166-", - "T133167-", - "C133168-", - "T133169-", - "T133170-", - "T133171-", - "C133172-", - "T133173-", - "T133224C", - "G133368A", - "T133493-", - "C133494-", - "G133495-", - "G133496-", - "T133497-", - "C133498-", - "C133499-", - "A133500-", - "T133501-", - "G133502-", - "T133503-", - "C133504-", - "T133505-", - "C133506-", - "C133507-", - "A133508-", - "T133509-", - "T133510-", - "G133511-", - "C133512-", - "T133513-", - "A133514-", - "C133515-", - "A133516-", - "C133517-", - "C133518-", - "A133519-", - "C133520-", - "C133521-", - "A133522-", - "T133523-", - "T133524-", - "A133525-", - "G133526-", - "A133527-", - "T133528-", - "T133529-", - "T133530-", - "A133531-", - "C133532-", - "A133533-", - "G133534-", - "G133535-", - "C133536-", - "T133537-", - "G133538-", - "C133539-", - "T133540-", - "A133541-", - "G133542-", - "T133543-", - "T133544-", - "G133545-", - "T133546-", - "C133547-", - "G133548-", - "T133549-", - "T133550-", - "C133551-", - "G133552-", - "A133553-", - "G133554-", - "A133555-", - "T133556-", - "C133557-", - "A133558-", - "G133559-", - "A133560-", - "A133561-", - "A133562-", - "T133563-", - "A133564-", - "C133565-", - "G133566-", - "T133567-", - "G133568-", - "T133569-", - "T133570-", - "T133571-", - "T133572-", - "C133573-", - "T133574-", - "T133575-", - "G133576-", - "G133577-", - "A133578-", - "A133579-", - "T133580-", - "G133581-", - "G133582-", - "A133583-", - "T133584-", - "T133585-", - "T133586-", - "C133587-", - "G133588-", - "T133589-", - "C133590-", - "G133591-", - "A133592-", - "T133593-", - "G133594-", - "T133595-", - "A133596-", - "C133597-", - "T133598-", - "T133599-", - "G133600-", - "T133601-", - "C133602-", - "A133603-", - "T133604-", - "G133605-", - "A133606-", - "T133607-", - "T133608-", - "G133609-", - "G133610-", - "C133611-", - "A133612-", - "T133613-", - "C133614-", - "G133615-", - "A133616-", - "A133617-", - "A133618-", - "C133619-", - "A133620-", - "C133621-", - "T133622-", - "T133623-", - "A133624-", - "T133625-", - "T133626-", - "A133627-", - "A133628-", - "G133629-", - "T133630-", - "T133631-", - "C133632-", - "T133633-", - "T133634-", - "T133635-", - "T133636-", - "T133637-", - "T133638-", - "T133639-", - "C133640-", - "A133641-", - "A133642-", - "T133643-", - "T133644-", - "C133645-", - "T133646-", - "A133647-", - "C133648-", - "G133649-", - "A133650-", - "T133651-", - "T133652-", - "T133653-", - "T133654-", - "A133655-", - "T133656-", - "T133657-", - "T133658-", - "C133659-", - "T133660-", - "T133661-", - "T133662-", - "C133663-", - "G133664-", - "C133665-", - "G133666-", - "A133667-", - "G133668-", - "T133669-", - "C133670-", - "A133671-", - "A133672-", - "T133673-", - "T133674-", - "C133675-", - "C133676-", - "C133677-", - "T133678-", - "C133679-", - "C133680-", - "T133681-", - "G133682-", - "T133683-", - "A133684-", - "G133685-", - "T133686-", - "A133687-", - "A133688-", - "C133689-", - "T133690-", - "A133691-", - "T133692-", - "C133693-", - "A133694-", - "G133695-", - "T133696-", - "T133697-", - "T133698-", - "T133699-", - "G133700-", - "T133701-", - "C133702-", - "A133703-", - "G133704-", - "A133705-", - "T133706-", - "T133707-", - "C133708-", - "A133709-", - "C133710-", - "G133711-", - "C133712-", - "T133713-", - "C133714-", - "T133715-", - "C133716-", - "T133717-", - "A133718-", - "C133719-", - "G133720-", - "T133721-", - "A133722-", - "G133723-", - "A133724-", - "C133725-", - "T133726-", - "T133727-", - "T133728-", - "C133729-", - "T133730-", - "T133731-", - "G133732-", - "C133733-", - "A133734-", - "A133735-", - "G133736-", - "T133737-", - "T133738-", - "A133739-", - "C133740-", - "T133741-", - "A133742-", - "A133743-", - "T133744-", - "T133745-", - "T133746-", - "G133747-", - "T133748-", - "T133749-", - "C133750-", - "C133751-", - "C133752-", - "T133753-", - "G133754-", - "G133755-", - "C133756-", - "A133757-", - "T133758-", - "T133759-", - "A133760-", - "C133761-", - "C133762-", - "G133763-", - "A133764-", - "G133765-", - "T133766-", - "T133767-", - "C133768-", - "A133769-", - "G133770-", - "T133771-", - "T133772-", - "T133773-", - "T133774-", - "A133775-", - "T133776-", - "A133777-", - "T133778-", - "G133779-", - "C133780-", - "C133781-", - "G133782-", - "A133783-", - "A133784-", - "T133785-", - "A133786-", - "G133787-", - "A133788-", - "G133789-", - "T133790-", - "T133791-", - "C133792-", - "T133793-", - "G133794-", - "A133795-", - "T133796-", - "T133797-", - "C133798-", - "A133799-", - "T133800-", - "C133801-", - "C133802-", - "T133803-", - "T133804-", - "T133805-", - "G133806-", - "A133807-", - "G133808-", - "A133809-", - "A133810-", - "G133811-", - "A133812-", - "T133813-", - "C133814-", - "T133815-", - "C133816-", - "T133817-", - "A133818-", - "G133819-", - "C133820-", - "G133821-", - "A133822-", - "T133823-", - "C133824-", - "G133825-", - "T133826-", - "T133827-", - "C133828-", - "A133829-", - "A133830-", - "G133831-", - "A133832-", - "T133833-", - "C133834-", - "C133835-", - "C133836-", - "T133837-", - "G133838-", - "A133839-", - "T133840-", - "T133841-", - "C133842-", - "T133843-", - "A133844-", - "G133845-", - "T133846-", - "C133847-", - "T133848-", - "T133849-", - "T133850-", - "A133851-", - "G133852-", - "C133853-", - "C133854-", - "T133855-", - "A133856-", - "T133857-", - "T133858-", - "T133859-", - "A133860-", - "C133861-", - "C133862-", - "T133863-", - "C133864-", - "C133865-", - "T133866-", - "C133867-", - "A133868-", - "G133869-", - "A133870-", - "A133871-", - "G133872-", - "A133873-", - "T133874-", - "G133875-", - "C133876-", - "T133877-", - "C133878-", - "C133879-", - "G133880-", - "T133881-", - "T133882-", - "A133883-", - "C133884-", - "C133885-", - "G133886-", - "T133887-", - "T133888-", - "T133889-", - "T133890-", - "T133891-", - "A133892-", - "C133893-", - "A133894-", - "A133895-", - "T133896-", - "C133897-", - "G133898-", - "T133899-", - "T133900-", - "A133901-", - "A133902-", - "G133903-", - "A133904-", - "T133905-", - "G133906-", - "T133907-", - "C133908-", - "T133909-", - "A133910-", - "T133911-", - "C133912-", - "A133913-", - "A133914-", - "G133915-", - "A133916-", - "T133917-", - "C133918-", - "C133919-", - "A133920-", - "T133921-", - "G133922-", - "A133923-", - "T133924-", - "T133925-", - "C133926-", - "T133927-", - "A133928-", - "T133929-", - "C133930-", - "T133931-", - "C133932-", - "T133933-", - "T133934-", - "T133935-", - "T133936-", - "C133937-", - "C133938-", - "A133939-", - "T133940-", - "A133941-", - "T133942-", - "C133943-", - "A133944-", - "G133945-", - "C134152T", - "G134354T", - "A135987T", - "G136015A", - "C136390A", - "A136864C", - "C137830T", - "T138627C", - "G138840T", - "T139424-", - "G139425-", - "T139426-", - "A140105-", - "T140106-", - "A140107-", - "A140108-", - "C140109-", - "A140110-", - "A140111-", - "T140112-", - "T140113-", - "G141071A", - "A141497G", - "G141759A", - "G142056A", - "C142159T", - "T142338C", - "A142752-", - "G143458-", - "T143743G", - "G143831A", - "C144025T", - "G144742A", - "C145303T", - "G145642T", - "A145892-", - "G145908A", - "T145976-", - "A145977-", - "A145978-", - "C146084-", - "G146085-", - "C146395A", - "G146494A", - "G146632T", - "T146860-", - "A146861-", - "T146869-", - "A146870-", - "T146871-", - "T146872-", - "T146873-", - "T146874-", - "A146875-", - "T146876-", - "A146877-", - "T146878-", - "T146879-", - "T146880-", - "A146964-", - "C147489T", - "G147780A", - "C147800T", - "A148336-", - "T148344A", - "A150156G", - "T150532-", - "A150549T", - "A150968T", - "A151015-", - "T151016-", - "G151017-", - "A151018-", - "C151019-", - "A151042-", - "T151289G", - "T152265-", - "T152266-", - "A152267-", - "G152328A", - "G154263A", - "T154351-", - "C154352-", - "C154389T", - "T154664A", - "C154791A", - "T155417-", - "C155483A", - "G155888A", - "A156206-", - "T156370-", - "T156371-", - "A156372-", - "C156373-", - "T156374-", - "G156375-", - "A156376-", - "C156377-", - "T156378-", - "A156379-", - "C156380-", - "A156381-", - "T156382-", - "G156383-", - "T156384-", - "A156385-", - "C156386-", - "T156387-", - "A156388-", - "T156389-", - "T156390-", - "T156391-", - "T156392-", - "A156393-", - "C156394-", - "A156395-", - "T156396-", - "T156397-", - "A156398-", - "C156399-", - "T156400-", - "A156401-", - "C156402-", - "A156403-", - "T156404-", - "T156405-", - "G156406-", - "G156407-", - "C156408-", - "T156409-", - "A156410-", - "C156411-", - "G156412-", - "G156413-", - "C156414-", - "A156415-", - "T156416-", - "A156417-", - "T156418-", - "A156419-", - "T156420-", - "A156421-", - "C156422-", - "C156423-", - "T156424-", - "A156425-", - "C156426-", - "T156427-", - "T156428-", - "C156429-", - "G156430-", - "T156431-", - "C156432-", - "A156433-", - "C156434-", - "T156435-", - "T156436-", - "C156437-", - "C156438-", - "A156439-", - "C156440-", - "A156441-", - "C156442-", - "G156443-", - "C156444-", - "T156445-", - "C156446-", - "C156447-", - "G156448-", - "G156449-", - "T156450-", - "A156451-", - "A156452-", - "A156453-", - "C156454-", - "G156455-", - "G156456-", - "G156457-", - "T156458-", - "G156459-", - "T156460-", - "C156461-", - "A156462-", - "T156463-", - "G156464-", - "T156465-", - "G156466-", - "A156467-", - "C156468-", - "G156469-", - "A156470-", - "G156471-", - "G156472-", - "G156473-", - "A156474-", - "G156475-", - "A156476-", - "A156477-", - "T156478-", - "C156479-", - "T156480-", - "T156481-", - "G156482-", - "A156483-", - "T156484-", - "A156485-", - "A156486-", - "G156487-", - "A156488-", - "G156489-", - "G156490-", - "C156491-", - "A156492-", - "T156493-", - "A156494-", - "A156495-", - "T156496-", - "C156497-", - "A156498-", - "A156499-", - "T156500-", - "G156501-", - "T156502-", - "T156503-", - "G156504-", - "T156505-", - "A156506-", - "A156507-", - "T156508-", - "C156509-", - "C156510-", - "G156511-", - "G156512-", - "T156513-", - "G156514-", - "T156515-", - "C156516-", - "C156517-", - "A156518-", - "C156519-", - "C156520-", - "T156521-", - "G156522-", - "G156523-", - "A156524-", - "G156525-", - "A156526-", - "A156527-", - "T156528-", - "T156529-", - "T156530-", - "G156531-", - "C156532-", - "C156533-", - "A156534-", - "A156535-", - "G156536-", - "G156537-", - "T156538-", - "C156539-", - "A156540-", - "G156541-", - "A156542-", - "T156543-", - "G156544-", - "T156545-", - "A156546-", - "G156547-", - "A156548-", - "G156549-", - "T156550-", - "T156551-", - "G156552-", - "G156553-", - "T156554-", - "A156555-", - "G156556-", - "T156557-", - "G156558-", - "A156559-", - "T156560-", - "A156561-", - "A156562-", - "C156563-", - "A156564-", - "C156565-", - "A156566-", - "A156567-", - "A156568-", - "A156569-", - "T156570-", - "G156571-", - "T156572-", - "G156573-", - "A156574-", - "A156575-", - "C156576-", - "A156577-", - "C156578-", - "T156579-", - "G156580-", - "C156581-", - "C156582-", - "C156583-", - "A156584-", - "C156585-", - "C156586-", - "T156587-", - "C156588-", - "A156589-", - "T156590-", - "A156591-", - "C156592-", - "A156593-", - "T156594-", - "A156595-", - "T156596-", - "A156597-", - "C156598-", - "C156599-", - "G156600-", - "C156601-", - "A156602-", - "A156603-", - "T156604-", - "C156605-", - "C156606-", - "C156607-", - "C156608-", - "A156609-", - "A156610-", - "T156611-", - "T156612-", - "A156613-", - "T156614-", - "T156615-", - "C156616-", - "T156617-", - "A156618-", - "A156619-", - "T156620-", - "A156621-", - "G156622-", - "A156623-", - "T156624-", - "G156625-", - "T156626-", - "C156627-", - "A156628-", - "T156629-", - "C156630-", - "A156631-", - "A156632-", - "T156633-", - "G156634-", - "T156635-", - "A156636-", - "G156637-", - "A156638-", - "A156639-", - "A156640-", - "A156641-", - "T156642-", - "G156643-", - "C156644-", - "C156645-", - "C156646-", - "A156647-", - "A156648-", - "C156649-", - "A156650-", - "G156651-", - "G156652-", - "A156653-", - "T156654-", - "C156655-", - "A156656-", - "T156657-", - "T156658-", - "T156659-", - "G156660-", - "A156661-", - "T156662-", - "A156663-", - "A156664-", - "G156665-", - "G156666-", - "T156667-", - "A156668-", - "A156669-", - "A156670-", - "G156671-", - "T156672-", - "G156673-", - "T156674-", - "A156675-", - "C156676-", - "C156677-", - "G156678-", - "G156679-", - "A156680-", - "A156681-", - "C156682-", - "A156683-", - "C156684-", - "A156685-", - "G156686-", - "A156687-", - "A156688-", - "C156689-", - "A156690-", - "A156691-", - "A156692-", - "T156693-", - "G156694-", - "T156695-", - "T156696-", - "C156697-", - "G156698-", - "T156699-", - "G156700-", - "T156701-", - "C156702-", - "A156703-", - "T156704-", - "C156705-", - "C156706-", - "T156707-", - "G156708-", - "G156709-", - "T156710-", - "T156711-", - "G156712-", - "G156713-", - "T156714-", - "A156715-", - "T156716-", - "A156717-", - "C156718-", - "G156719-", - "C156720-", - "T156721-", - "A156722-", - "C156723-", - "T156724-", - "G156725-", - "A156726-", - "T156727-", - "T156728-", - "C156729-", - "T156730-", - "T156731-", - "C156732-", - "A156733-", - "C156734-", - "A156735-", - "G156736-", - "A156737-", - "C156738-", - "T156739-", - "G156740-", - "A156741-", - "A156742-", - "G156743-", - "A156744-", - "T156745-", - "T156746-", - "G156747-", - "T156748-", - "C156749-", - "G156750-", - "A156751-", - "G156752-", - "A156753-", - "T156754-", - "T156755-", - "T156756-", - "G156757-", - "T156758-", - "G156759-", - "T156760-", - "A156761-", - "C156762-", - "C156763-", - "A156764-", - "A156765-", - "A156766-", - "A156767-", - "A156768-", - "A156769-", - "G156770-", - "G156771-", - "A156772-", - "G156773-", - "A156774-", - "T156775-", - "G156776-", - "T156777-", - "C156778-", - "C156779-", - "A156780-", - "T156781-", - "G156782-", - "C156783-", - "G156784-", - "G156785-", - "A156786-", - "T156787-", - "A156788-", - "C156789-", - "T156790-", - "T156791-", - "T156792-", - "G156793-", - "G156794-", - "T156795-", - "G156796-", - "G156797-", - "A156798-", - "A156799-", - "T156800-", - "A156801-", - "G156802-", - "A156803-", - "T156804-", - "G156805-", - "A156806-", - "A156807-", - "G156808-", - "G156809-", - "A156810-", - "A156811-", - "A156812-", - "T156813-", - "C156814-", - "C156815-", - "T156816-", - "A156817-", - "T156818-", - "T156819-", - "T156820-", - "G156821-", - "T156822-", - "A156823-", - "A156824-", - "A156825-", - "T156826-", - "C156827-", - "G156828-", - "T156829-", - "G156830-", - "T156831-", - "T156832-", - "G156833-", - "T156834-", - "G156835-", - "T156836-", - "T156837-", - "G156838-", - "G156839-", - "T156840-", - "G156841-", - "A156842-", - "A156843-", - "T156844-", - "A156845-", - "T156846-", - "T156847-", - "G156848-", - "C156849-", - "G156850-", - "A156851-", - "C156852-", - "T156853-", - "A156854-", - "C156855-", - "C156856-", - "T156857-", - "A156858-", - "C156859-", - "G156860-", - "T156861-", - "A156862-", - "A156863-", - "T156864-", - "T156865-", - "A156866-", - "T156867-", - "A156868-", - "G156869-", - "A156870-", - "C156871-", - "T156872-", - "T156873-", - "G156874-", - "A156875-", - "T156876-", - "C156877-", - "C156878-", - "A156879-", - "T156880-", - "T156881-", - "T156882-", - "C156883-", - "C156884-", - "T156885-", - "C156886-", - "C156887-", - "A156888-", - "T156889-", - "G156890-", - "C156891-", - "A156892-", - "A156893-", - "A156894-", - "C156895-", - "T156896-", - "A156897-", - "T156898-", - "C156899-", - "T156900-", - "A156901-", - "T156902-", - "C156903-", - "T156904-", - "A156905-", - "A156906-", - "A156907-", - "T156908-", - "G156909-", - "T156910-", - "A156911-", - "A156912-", - "T156913-", - "T156914-", - "A156915-", - "A156916-", - "T156917-", - "T156918-", - "A156919-", - "T156920-", - "G156921-", - "A156922-", - "T156923-", - "T156924-", - "T156925-", - "T156926-", - "G156927-", - "A156928-", - "T156929-", - "G156930-", - "A156931-", - "T156932-", - "A156933-", - "A156934-", - "T156935-", - "G156936-", - "T156937-", - "T156938-", - "A156939-", - "C156940-", - "C156941-", - "A156942-", - "T156943-", - "A156944-", - "C156945-", - "A156946-", - "T156947-", - "T156948-", - "A156949-", - "T156950-", - "A156951-", - "T156952-", - "C156953-", - "G156954-", - "C156955-", - "T156956-", - "A156957-", - "C156958-", - "T156959-", - "T156960-", - "G156961-", - "G156962-", - "T156963-", - "T156964-", - "A156965-", - "G156966-", - "T156967-", - "G156968-", - "T156969-", - "G156970-", - "T156971-", - "A156972-", - "T156973-", - "T156974-", - "A156975-", - "T156976-", - "T156977-", - "C156978-", - "A156979-", - "G156980-", - "T156981-", - "A156982-", - "T156983-", - "G156984-", - "G156985-", - "A156986-", - "A156987-", - "G156988-", - "A156989-", - "C156990-", - "C156991-", - "T156992-", - "A156993-", - "T156994-", - "T156995-", - "A156996-", - "A156997-", - "T156998-", - "A156999-", - "A157000-", - "T157001-", - "T157002-", - "A157003-", - "C157004-", - "T157005-", - "T157006-", - "A157007-", - "T157008-", - "C157009-", - "T157010-", - "T157011-", - "T157012-", - "T157013-", - "G157014-", - "A157015-", - "C157016-", - "G157017-", - "A157018-", - "T157019-", - "C157020-", - "T157021-", - "T157022-", - "G157023-", - "T157024-", - "T157025-", - "A157026-", - "T157027-", - "A157028-", - "A157029-", - "T157030-", - "T157031-", - "A157032-", - "T157033-", - "A157034-", - "A157035-", - "T157036-", - "A157037-", - "T157038-", - "A157039-", - "A157040-", - "A157041-", - "A157042-", - "A157043-", - "T157044-", - "A157045-", - "C157046-", - "T157047-", - "T157048-", - "A157049-", - "T157050-", - "G157051-", - "A157052-", - "C157053-", - "A157054-", - "T157055-", - "A157056-", - "G157057-", - "T157058-", - "A157059-", - "A157060-", - "C157061-", - "T157062-", - "C157063-", - "A157064-", - "T157065-", - "A157066-", - "A157067-", - "T157068-", - "T157069-", - "G157070-", - "C157071-", - "T157072-", - "G157073-", - "A157074-", - "C157075-", - "G157076-", - "C157077-", - "G157078-", - "A157079-", - "T157080-", - "A157081-", - "A157082-", - "A157083-", - "T157084-", - "T157085-", - "C157086-", - "G157087-", - "T157088-", - "A157089-", - "A157090-", - "T157091-", - "A157092-", - "A157093-", - "T157094-", - "C157095-", - "T157096-", - "G157097-", - "T157098-", - "T157099-", - "T157100-", - "T157101-", - "G157102-", - "T157103-", - "T157104-", - "C157105-", - "A157106-", - "A157107-", - "A157108-", - "T157109-", - "T157110-", - "T157111-", - "T157112-", - "T157113-", - "A157114-", - "T157115-", - "A157116-", - "A157117-", - "G157118-", - "G157119-", - "A157120-", - "A157121-", - "T157122-", - "C157123-", - "T157124-", - "A157125-", - "C157126-", - "A157127-", - "G157128-", - "G157129-", - "C157130-", - "A157131-", - "T157132-", - "A157133-", - "A157134-", - "A157135-", - "A157136-", - "A157137-", - "T157138-", - "A157139-", - "A157140-", - "A157141-", - "A157142-", - "A157143-", - "T157144-", - "A157145-", - "T157146-", - "A157147-", - "A157148-", - "T157149-", - "C157150-", - "T157151-", - "A157152-", - "T157153-", - "A157154-", - "A157155-", - "T157156-", - "A157157-", - "T157158-", - "A157159-", - "C157160-", - "T157161-", - "C157162-", - "T157163-", - "T157164-", - "A157165-", - "C157166-", - "A157167-", - "A157168-", - "C157169-", - "G157170-", - "C157171-", - "C157172-", - "A157173-", - "T157174-", - "C157175-", - "A157176-", - "T157177-", - "G157178-", - "A157179-", - "A157180-", - "T157181-", - "A157182-", - "G157183-", - "C157184-", - "A157185-", - "G157186-", - "T157187-", - "G157188-", - "A157189-", - "A157190-", - "T157191-", - "T157192-", - "A157193-", - "A157194-", - "T157195-", - "T157196-", - "G157197-", - "C157198-", - "T157199-", - "G157200-", - "T157201-", - "T157202-", - "A157203-", - "T157204-", - "T157205-", - "A157206-", - "T157207-", - "G157208-", - "G157209-", - "A157210-", - "T157211-", - "T157212-", - "T157213-", - "A157214-", - "G157215-", - "A157216-", - "A157217-", - "A157218-", - "T157219-", - "A157220-", - "G157221-", - "T157222-", - "G157223-", - "G157224-", - "A157225-", - "C157226-", - "G157227-", - "A157228-", - "T157229-", - "T157230-", - "T157231-", - "T157232-", - "G157233-", - "T157234-", - "G157235-", - "A157236-", - "T157237-", - "A157238-", - "T157239-", - "T157240-", - "A157241-", - "A157242-", - "T157243-", - "A157244-", - "T157245-", - "A157246-", - "G157247-", - "T157248-", - "T157249-", - "A157250-", - "T157251-", - "T157252-", - "A157253-", - "A157254-", - "T157255-", - "G157256-", - "A157257-", - "T157258-", - "G157259-", - "A157260-", - "A157261-", - "A157262-", - "G157263-", - "G157264-", - "A157265-", - "T157266-", - "A157267-", - "A157268-", - "A157269-", - "C157270-", - "G157271-", - "C157272-", - "T157273-", - "C157274-", - "A157275-", - "T157276-", - "A157277-", - "G157278-", - "A157279-", - "C157280-", - "T157281-", - "C157282-", - "A157283-", - "T157284-", - "C157285-", - "C157286-", - "T157287-", - "A157288-", - "T157289-", - "C157290-", - "T157291-", - "G157292-", - "G157293-", - "A157294-", - "G157295-", - "C157296-", - "C157297-", - "T157298-", - "C157299-", - "C157300-", - "G157301-", - "A157302-", - "A157303-", - "T157304-", - "A157305-", - "T157306-", - "T157307-", - "T157308-", - "T157309-", - "T157310-", - "T157311-", - "C157312-", - "C157313-", - "A157314-", - "T157315-", - "T157316-", - "C157317-", - "T157318-", - "G157319-", - "T157320-", - "T157321-", - "T157322-", - "T157323-", - "C157324-", - "C157325-", - "A157326-", - "A157327-", - "T157328-", - "A157329-", - "A157330-", - "T157331-", - "T157332-", - "T157333-", - "T157334-", - "A157335-", - "T157336-", - "C157337-", - "G157338-", - "A157339-", - "T157340-", - "T157341-", - "C157342-", - "T157343-", - "A157344-", - "A157345-", - "T157346-", - "G157347-", - "A157348-", - "A157349-", - "T157350-", - "A157351-", - "C157352-", - "G157353-", - "A157354-", - "A157355-", - "G157356-", - "T157357-", - "T157358-", - "A157359-", - "A157360-", - "T157361-", - "C157362-", - "T157363-", - "A157364-", - "A157365-", - "G157366-", - "T157367-", - "C157368-", - "A157369-", - "T157370-", - "T157371-", - "T157372-", - "A157373-", - "G157374-", - "A157375-", - "T157376-", - "T157377-", - "A157378-", - "T157379-", - "C157380-", - "A157381-", - "A157382-", - "A157383-", - "G157384-", - "T157385-", - "G157386-", - "T157387-", - "T157388-", - "A157389-", - "A157390-", - "C157391-", - "T157392-", - "A157393-", - "T157394-", - "T157395-", - "T157396-", - "G157397-", - "A157398-", - "T157399-", - "C157400-", - "G157401-", - "A157402-", - "T157403-", - "T157404-", - "A157405-", - "C157406-", - "A157407-", - "T157408-", - "T157409-", - "T157410-", - "A157411-", - "T157412-", - "G157413-", - "G157414-", - "G157415-", - "A157416-", - "T157417-", - "A157418-", - "C157419-", - "C157420-", - "T157421-", - "T157422-", - "T157423-", - "G157424-", - "A157425-", - "G157426-", - "C157427-", - "C157428-", - "T157429-", - "A157430-", - "A157431-", - "C157432-", - "T157433-", - "A157434-", - "A157435-", - "C157436-", - "G157437-", - "A157438-", - "T157439-", - "A157440-", - "A157441-", - "C157442-", - "G157443-", - "T157444-", - "G157445-", - "A157446-", - "A157447-", - "A157448-", - "T157449-", - "A157450-", - "T157451-", - "A157452-", - "T157453-", - "T157454-", - "C157455-", - "T157456-", - "T157457-", - "T157458-", - "C157459-", - "A157460-", - "A157461-", - "C157462-", - "C157463-", - "G157464-", - "C157465-", - "T157466-", - "G157467-", - "A157468-", - "T157469-", - "T157470-", - "T157471-", - "T157472-", - "T157473-", - "T157474-", - "T157475-", - "A157476-", - "C157477-", - "A157478-", - "A157479-", - "A157480-", - "T157481-", - "T157482-", - "G157483-", - "G157484-", - "A157485-", - "T157486-", - "C157487-", - "T157488-", - "G157489-", - "C157490-", - "C157491-", - "A157492-", - "T157493-", - "T157494-", - "A157495-", - "C157496-", - "T157497-", - "G157498-", - "A157499-", - "G157500-", - "T157501-", - "G157502-", - "C157503-", - "G157504-", - "A157505-", - "A157506-", - "A157507-", - "A157508-", - "A157509-", - "T157510-", - "A157511-", - "C157512-", - "A157513-", - "T157514-", - "A157515-", - "C157516-", - "T157517-", - "T157518-", - "A157519-", - "A157520-", - "A157521-", - "A157522-", - "A157523-", - "T157524-", - "C157525-", - "T157526-", - "T157527-", - "T157528-", - "G157529-", - "T157530-", - "T157531-", - "T157532-", - "T157533-", - "A157534-", - "G157535-", - "A157536-", - "A157537-", - "A157538-", - "C157539-", - "T157540-", - "G157541-", - "T157542-", - "A157543-", - "T157544-", - "C157545-", - "G157546-", - "A157547-", - "T157548-", - "T157549-", - "T157550-", - "C157551-", - "T157552-", - "A157553-", - "C157554-", - "A157555-", - "T157556-", - "A157557-", - "T157558-", - "A157559-", - "C157560-", - "G157561-", - "C157562-", - "T157563-", - "G157564-", - "A157565-", - "T157566-", - "A157567-", - "A157568-", - "A157569-", - "T157570-", - "A157571-", - "T157572-", - "A157573-", - "A157574-", - "T157575-", - "A157576-", - "A157577-", - "C157578-", - "A157579-", - "A157580-", - "G157581-", - "A157582-", - "A157583-", - "A157584-", - "A157585-", - "T157586-", - "A157587-", - "G157588-", - "A157589-", - "A157590-", - "T157591-", - "T157592-", - "A157593-", - "G157594-", - "C157595-", - "A157596-", - "T157597-", - "C157598-", - "G157599-", - "T157600-", - "T157601-", - "T157602-", - "A157603-", - "A157604-", - "C157605-", - "A157606-", - "C157607-", - "A157608-", - "A157609-", - "T157610-", - "A157611-", - "T157612-", - "T157613-", - "A157614-", - "C157615-", - "G157616-", - "A157617-", - "A157618-", - "A157619-", - "T157620-", - "A157621-", - "T157622-", - "T157623-", - "T157624-", - "T157625-", - "G157626-", - "A157627-", - "G157628-", - "A157629-", - "C157630-", - "T157631-", - "C157632-", - "A157633-", - "T157634-", - "C157635-", - "A157636-", - "A157637-", - "C157638-", - "A157639-", - "A157640-", - "T157641-", - "G157642-", - "A157643-", - "A157644-", - "A157645-", - "A157646-", - "C157647-", - "T157648-", - "T157649-", - "T157650-", - "A157651-", - "A157652-", - "A157653-", - "T157654-", - "A157655-", - "C157656-", - "T157657-", - "T157658-", - "A157659-", - "A157660-", - "C157661-", - "A157662-", - "G157663-", - "A157664-", - "G157665-", - "G157666-", - "A157667-", - "A157668-", - "T157669-", - "C157670-", - "A157671-", - "A157672-", - "T157673-", - "G157674-", - "A157675-", - "T157676-", - "A157677-", - "A157678-", - "A157679-", - "A157680-", - "A157681-", - "T157682-", - "T157683-", - "T157684-", - "T157685-", - "A157686-", - "A157687-", - "G157688-", - "C157689-", - "G157690-", - "A157691-", - "T157692-", - "G157693-", - "A157694-", - "T157695-", - "A157696-", - "T157697-", - "G157698-", - "T157699-", - "T157700-", - "A157701-", - "T157702-", - "A157703-", - "T157704-", - "A157705-", - "T157706-", - "A157707-", - "A157708-", - "A157709-", - "A157710-", - "A157711-", - "A157712-", - "T157713-", - "G157714-", - "A157715-", - "G157716-", - "G157717-", - "A157718-", - "T157719-", - "T157720-", - "T157721-", - "C157722-", - "A157723-", - "C157724-", - "C157725-", - "C157726-", - "C157727-", - "A157728-", - "C157729-", - "T157730-", - "G157731-", - "A157732-", - "T157733-", - "T157734-", - "C157735-", - "T157736-", - "C157737-", - "A157738-", - "T157739-", - "T157740-", - "A157741-", - "A157742-", - "A157743-", - "T157744-", - "G157745-", - "G157746-", - "T157747-", - "T157748-", - "A157749-", - "G157750-", - "A157751-", - "G157752-", - "A157753-", - "G157754-", - "T157755-", - "A157756-", - "C157757-", - "A157758-", - "C157759-", - "C157760-", - "A157761-", - "A157762-", - "C157763-", - "C157764-", - "A157765-", - "T157766-", - "G157767-", - "T157768-", - "A157769-", - "C157770-", - "C157771-", - "G157772-", - "T157773-", - "C157774-", - "G157775-", - "A157776-", - "G157777-", - "T157778-", - "T157779-", - "A157780-", - "C157781-", - "T157782-", - "T157783-", - "A157784-", - "G157785-", - "A157786-", - "T157787-", - "G157788-", - "C157789-", - "C157790-", - "T157791-", - "C157792-", - "A157793-", - "G157794-", - "A157795-", - "A157796-", - "T157797-", - "A157798-", - "T157799-", - "C157800-", - "A157801-", - "T157802-", - "T157803-", - "T157804-", - "C157805-", - "T157806-", - "T157807-", - "T157808-", - "C157809-", - "C157810-", - "C157811-", - "C157812-", - "A157813-", - "C157814-", - "A157815-", - "A157816-", - "G157817-", - "T157818-", - "T157819-", - "A157820-", - "T157821-", - "A157822-", - "A157823-", - "A157824-", - "A157825-", - "T157826-", - "C157827-", - "A157828-", - "C157829-", - "T157830-", - "T157831-", - "T157832-", - "A157833-", - "T157834-", - "A157835-", - "G157836-", - "T157837-", - "C157838-", - "A157839-", - "T157840-", - "C157841-", - "G157842-", - "A157843-", - "C157844-", - "T157845-", - "G157846-", - "G157847-", - "T157848-", - "T157849-", - "A157850-", - "G157851-", - "T157852-", - "T157853-", - "C157854-", - "A157855-", - "A157856-", - "T157857-", - "C157858-", - "T157859-", - "A157860-", - "C157861-", - "G157862-", - "A157863-", - "A157864-", - "T157865-", - "G157866-", - "T157867-", - "A157868-", - "T157869-", - "A157870-", - "A157871-", - "C157872-", - "A157873-", - "T157874-", - "T157875-", - "C157876-", - "T157877-", - "T157878-", - "A157879-", - "A157880-", - "A157881-", - "C157882-", - "A157883-", - "A157884-", - "T157885-", - "A157886-", - "T157887-", - "A157888-", - "G157889-", - "C157890-", - "A157891-", - "T157892-", - "T157893-", - "C157894-", - "T157895-", - "T157896-", - "G157897-", - "G157898-", - "A157899-", - "T157900-", - "A157901-", - "A157902-", - "A157903-", - "T157904-", - "C157905-", - "A157906-", - "T157907-", - "T157908-", - "T157909-", - "C157910-", - "C157911-", - "T157912-", - "A157913-", - "G157914-", - "A157915-", - "T157916-", - "A157917-", - "C157918-", - "C157919-", - "A157920-", - "T157921-", - "A157922-", - "T157923-", - "C157924-", - "A157925-", - "T157926-", - "C157927-", - "G157928-", - "A157929-", - "G157930-", - "T157931-", - "T157932-", - "G157933-", - "A157934-", - "T157935-", - "A157936-", - "T157937-", - "C157938-", - "T157939-", - "A157940-", - "T157941-", - "C157942-", - "G157943-", - "G157944-", - "T157945-", - "A157946-", - "T157947-", - "A157948-", - "A157949-", - "G157950-", - "T157951-", - "A157952-", - "A157953-", - "T157954-", - "T157955-", - "C157956-", - "A157957-", - "C157958-", - "A157959-", - "T157960-", - "G157961-", - "A157962-", - "T157963-", - "A157964-", - "A157965-", - "G157966-", - "A157967-", - "T157968-", - "T157969-", - "T157970-", - "C157971-", - "C157972-", - "A157973-", - "T157974-", - "A157975-", - "A157976-", - "A157977-", - "C157978-", - "T157979-", - "G157980-", - "C157981-", - "T157982-", - "A157983-", - "C157984-", - "A157985-", - "A157986-", - "T157987-", - "C157988-", - "A157989-", - "T157990-", - "A157991-", - "A157992-", - "A157993-", - "A157994-", - "A157995-", - "A157996-", - "A157997-", - "T157998-", - "T157999-", - "C158000-", - "A158001-", - "T158002-", - "G158003-", - "G158004-", - "G158005-", - "A158006-", - "A158007-", - "A158008-", - "T158009-", - "G158010-", - "A158011-", - "T158012-", - "A158013-", - "T158014-", - "C158015-", - "T158016-", - "T158017-", - "C158018-", - "A158019-", - "C158020-", - "G158021-", - "T158022-", - "A158023-", - "G158024-", - "A158025-", - "T158026-", - "A158027-", - "T158028-", - "A158029-", - "G158030-", - "G158031-", - "T158032-", - "G158033-", - "T158034-", - "A158035-", - "G158036-", - "T158037-", - "T158038-", - "T158039-", - "C158040-", - "G158041-", - "C158042-", - "A158043-", - "G158044-", - "T158045-", - "G158046-", - "A158047-", - "C158048-", - "C158049-", - "G158050-", - "T158051-", - "C158052-", - "C158053-", - "T158054-", - "G158055-", - "G158056-", - "A158057-", - "T158058-", - "A158059-", - "A158060-", - "T158061-", - "A158062-", - "T158063-", - "T158064-", - "A158065-", - "T158066-", - "C158067-", - "T158068-", - "A158069-", - "T158070-", - "A158071-", - "T158072-", - "G158073-", - "A158074-", - "T158075-", - "G158076-", - "G158077-", - "G158078-", - "T158079-", - "G158080-", - "G158081-", - "A158082-", - "T158083-", - "A158084-", - "T158085-", - "G158086-", - "A158087-", - "T158088-", - "C158089-", - "A158090-", - "G158091-", - "T158092-", - "C158093-", - "C158094-", - "C158095-", - "T158096-", - "G158097-", - "T158098-", - "A158099-", - "T158100-", - "A158101-", - "G158102-", - "A158103-", - "A158104-", - "G158105-", - "T158106-", - "T158107-", - "C158108-", - "A158109-", - "A158110-", - "A158111-", - "G158112-", - "G158113-", - "T158114-", - "T158115-", - "A158116-", - "T158117-", - "A158118-", - "G158119-", - "C158120-", - "G158121-", - "T158122-", - "A158123-", - "C158124-", - "A158125-", - "A158126-", - "T158127-", - "A158128-", - "C158129-", - "A158130-", - "T158131-", - "G158132-", - "T158133-", - "A158134-", - "C158135-", - "T158136-", - "A158137-", - "A158138-", - "T158139-", - "T158140-", - "C158141-", - "T158142-", - "T158143-", - "G158144-", - "G158145-", - "A158146-", - "T158147-", - "A158148-", - "T158149-", - "A158150-", - "T158151-", - "G158152-", - "A158153-", - "T158154-", - "A158155-", - "T158156-", - "A158157-", - "C158158-", - "C158159-", - "A158160-", - "G158161-", - "A158162-", - "G158163-", - "C158164-", - "T158165-", - "A158166-", - "A158167-", - "A158168-", - "A158169-", - "A158170-", - "T158171-", - "A158172-", - "T158173-", - "C158174-", - "C158175-", - "T158176-", - "C158177-", - "G158178-", - "T158179-", - "T158180-", - "C158181-", - "T158182-", - "A158183-", - "A158184-", - "T158185-", - "T158186-", - "G158187-", - "C158188-", - "G158189-", - "G158190-", - "A158191-", - "G158192-", - "G158193-", - "A158194-", - "G158195-", - "T158196-", - "T158197-", - "G158198-", - "C158199-", - "C158200-", - "A158201-", - "A158202-", - "T158203-", - "G158204-", - "A158205-", - "C158206-", - "G158207-", - "A158208-", - "A158209-", - "T158210-", - "A158211-", - "C158212-", - "A158213-", - "T158214-", - "T158215-", - "T158216-", - "A158217-", - "T158218-", - "T158219-", - "G158220-", - "T158221-", - "A158222-", - "T158223-", - "A158224-", - "G158225-", - "G158226-", - "C158227-", - "G158228-", - "G158229-", - "T158230-", - "A158231-", - "T158232-", - "A158233-", - "C158234-", - "G158235-", - "C158236-", - "G158237-", - "A158238-", - "T158239-", - "C158240-", - "A158241-", - "G158242-", - "G158243-", - "A158244-", - "G158245-", - "T158246-", - "C158247-", - "A158248-", - "T158249-", - "C158250-", - "G158251-", - "T158252-", - "T158253-", - "G158254-", - "A158255-", - "T158256-", - "A158257-", - "T158258-", - "C158259-", - "T158260-", - "A158261-", - "G158262-", - "T158263-", - "A158264-", - "T158265-", - "C158266-", - "G158267-", - "A158268-", - "T158269-", - "A158270-", - "G158271-", - "A158272-", - "T158273-", - "G158274-", - "G158275-", - "A158276-", - "A158277-", - "G158278-", - "C158279-", - "C158280-", - "A158281-", - "T158282-", - "C158283-", - "A158284-", - "A158285-", - "A158286-", - "A158287-", - "C158288-", - "C158289-", - "A158290-", - "T158291-", - "A158292-", - "T158293-", - "T158294-", - "G158295-", - "G158296-", - "C158297-", - "A158298-", - "G158299-", - "A158300-", - "A158301-", - "G158302-", - "T158303-", - "A158304-", - "T158305-", - "G158306-", - "C158307-", - "T158308-", - "A158309-", - "A158310-", - "A158311-", - "A158312-", - "T158313-", - "G158314-", - "T158315-", - "G158316-", - "C158317-", - "G158318-", - "A158319-", - "A158320-", - "C158321-", - "C158322-", - "A158323-", - "A158324-", - "A158325-", - "A158326-", - "T158327-", - "G158328-", - "T158329-", - "G158330-", - "A158331-", - "T158332-", - "A158333-", - "T158334-", - "G158335-", - "G158336-", - "G158337-", - "G158338-", - "T158339-", - "T158340-", - "G158341-", - "C158342-", - "G158343-", - "A158344-", - "T158345-", - "T158346-", - "T158347-", - "T158348-", - "A158349-", - "A158350-", - "A158351-", - "C158352-", - "G158353-", - "G158354-", - "A158355-", - "T158356-", - "T158357-", - "A158358-", - "A158359-", - "T158360-", - "A158361-", - "T158362-", - "A158363-", - "T158364-", - "G158365-", - "T158366-", - "C158367-", - "A158368-", - "T158369-", - "A158370-", - "G158371-", - "G158372-", - "T158373-", - "G158374-", - "G158375-", - "A158376-", - "G158377-", - "T158378-", - "C158379-", - "G158380-", - "T158381-", - "T158382-", - "A158383-", - "A158384-", - "A158385-", - "G158386-", - "G158387-", - "T158388-", - "G158389-", - "A158390-", - "C158391-", - "A158392-", - "C158393-", - "A158394-", - "C158395-", - "A158396-", - "T158397-", - "G158398-", - "T158399-", - "A158400-", - "C158401-", - "C158402-", - "G158403-", - "A158404-", - "C158405-", - "G158406-", - "C158407-", - "A158408-", - "C158409-", - "T158410-", - "A158411-", - "G158412-", - "A158413-", - "G158414-", - "A158415-", - "G158416-", - "T158417-", - "T158418-", - "T158419-", - "A158420-", - "T158421-", - "C158422-", - "A158423-", - "G158424-", - "A158425-", - "A158426-", - "G158427-", - "A158428-", - "T158429-", - "G158430-", - "G158431-", - "A158432-", - "T158433-", - "G158434-", - "G158435-", - "A158436-", - "T158437-", - "G158438-", - "A158439-", - "A158440-", - "T158441-", - "C158442-", - "A158443-", - "T158444-", - "C158445-", - "A158446-", - "A158447-", - "C158448-", - "G158449-", - "T158450-", - "C158451-", - "T158452-", - "T158453-", - "C158454-", - "C158455-", - "A158456-", - "A158457-", - "T158458-", - "A158459-", - "A158460-", - "A158461-", - "A158462-", - "A158463-", - "T158464-", - "G158465-", - "T158466-", - "C158467-", - "C158468-", - "A158469-", - "A158470-", - "T158471-", - "A158472-", - "T158473-", - "G158474-", - "T158475-", - "C158476-", - "G158477-", - "A158478-", - "C158479-", - "G158480-", - "A158481-", - "T158482-", - "T158483-", - "G158484-", - "T158485-", - "T158486-", - "C158487-", - "A158488-", - "T158489-", - "G158490-", - "C158491-", - "T158492-", - "G158493-", - "G158494-", - "A158495-", - "A158496-", - "A158497-", - "G158498-", - "A158499-", - "T158500-", - "T158501-", - "T158502-", - "A158503-", - "T158504-", - "A158505-", - "T158506-", - "A158507-", - "T158508-", - "C158509-", - "T158510-", - "G158511-", - "G158512-", - "A158513-", - "G158514-", - "G158515-", - "T158516-", - "T158517-", - "A158518-", - "C158519-", - "A158520-", - "A158521-", - "C158522-", - "A158523-", - "A158524-", - "T158525-", - "A158526-", - "G158527-", - "T158528-", - "A158529-", - "G158530-", - "T158531-", - "G158532-", - "T158533-", - "A158534-", - "G158535-", - "T158536-", - "T158537-", - "A158538-", - "A158539-", - "T158540-", - "G158541-", - "T158542-", - "A158543-", - "A158544-", - "T158545-", - "A158546-", - "T158547-", - "C158548-", - "G158549-", - "A158550-", - "A158551-", - "T158552-", - "C158553-", - "T158554-", - "A158555-", - "G158556-", - "T158557-", - "C158558-", - "C158559-", - "T158560-", - "T158561-", - "A158562-", - "G158563-", - "C158564-", - "T158565-", - "A158566-", - "T158567-", - "A158568-", - "A158569-", - "T158570-", - "C158571-", - "C158572-", - "G158573-", - "A158574-", - "T158575-", - "A158576-", - "T158577-", - "A158578-", - "T158579-", - "G158580-", - "A158581-", - "T158582-", - "G158583-", - "A158584-", - "A158585-", - "T158586-", - "G158587-", - "G158588-", - "A158589-", - "C158590-", - "C158591-", - "A158592-", - "A158593-", - "A158594-", - "T158595-", - "T158596-", - "A158597-", - "T158598-", - "C158599-", - "A158600-", - "T158601-", - "C158602-", - "A158603-", - "T158604-", - "T158605-", - "A158606-", - "A158607-", - "A158608-", - "T158609-", - "A158610-", - "T158611-", - "T158612-", - "C158613-", - "C158614-", - "T158615-", - "A158616-", - "G158617-", - "A158618-", - "A158619-", - "T158620-", - "T158621-", - "A158622-", - "A158623-", - "T158624-", - "C158625-", - "C158626-", - "T158627-", - "G158628-", - "C158629-", - "T158630-", - "C158631-", - "T158632-", - "A158633-", - "T158751G", - "T160039A", - "A160041T", - "C160042A", - "G160043C", - "C160057A", - "A160270G", - "C161356T", - "A161579G", - "T161591C", - "T162384C", - "G162388A", - "C162447T", - "T162852A", - "T163190-", - "A163191-", - "A163192-", - "C163193-", - "T163194-", - "A163195-", - "A163196-", - "C163197-", - "C163256T", - "A163886G", - "G164849A", - "C166006T", - "C166196T", - "C166309A", - "T166655-", - "T166656-", - "T166711-", - "G167029A", - "C168226T", - "C168466A", - "C169125T", - "G169672A", - "T169792-", - "G170914-", - "C170999T", - "T172059-", - "A172550G", - "C172644T", - "C172671T", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "A173300-", - "T173301-", - "A173302-", - "T173303-", - "A173304-", - "T173305-", - "G173363T", - "G173436A", - "C173474T", - "T173498-", - "A173499-", - "T173740-", - "A174044T", - "C174102A", - "C174146T", - "G174183T", - "G174519-", - "A174520-", - "T174521-", - "G174522-", - "A174523-", - "A174524-", - "G174525-", - "A174526-", - "T174527-", - "G174528-", - "A174529-", - "A174530-", - "T174855C", - "G177853A", - "A178326-", - "C178702T", - "T179226-", - "C179366T", - "A180163G", - "T180435A", - "A180548G", - "C180578T", - "T181102-", - "A181103-", - "T181104-", - "A181105-", - "T181106-", - "T181107-", - "C181108-", - "C181109-", - "T181110-", - "T181233C", - "C181351T", - "C181648A", - "A181790G", - "G181872A", - "A182356T", - "T182899C", - "T183553-", - "A183554-", - "C183555-", - "T184979C", - "C186840T", - "G187145A", - "T187207-", - "C187533A", - "T187770-", - "G187896T", - "A188871G", - "C189206T", - "C189609T", - "T189739-", - "A189896G", - "A190198-", - "C190199-", - "T190395-", - "T191134C", - "A192435-", - "A192436-", - "G192437-", - "T192438-", - "C192439-", - "A192440-", - "T192441-", - "A192442-", - "A192443-", - "G192444-", - "T192445-", - "T192446-", - "A192447-", - "G192448-", - "T192449-", - "T192450-", - "A192451-", - "A192452-", - "G192453-", - "T192454-", - "C192455-", - "A192456-", - "T192457-", - "A192458-", - "A192459-", - "G192460-", - "T192461-", - "T192462-", - "A192463-", - "G192464-", - "T192465-", - "T192466-", - "A192467-", - "A192468-", - "G192469-", - "T192470-", - "T192471-", - "A192472-", - "T192473-", - "A192474-", - "A192475-", - "G192476-", - "T192477-", - "T192478-", - "A192479-", - "G192480-", - "T192481-", - "T192482-", - "A192483-", - "A192484-", - "G192485-", - "T192486-", - "C192487-", - "A192488-", - "T192489-", - "A192490-", - "A192491-", - "G192492-", - "T192493-", - "T192494-", - "A192495-", - "G192496-", - "T192497-", - "T192498-", - "A192499-", - "A192500-", - "G192501-", - "T192502-", - "C192503-", - "A192504-", - "T192505-", - "A192506-", - "A192507-", - "G192508-", - "T192509-", - "T192510-", - "A192511-", - "G192512-", - "T192513-", - "T192514-", - "A192515-", - "A192516-", - "G192517-", - "C193168T", - "G194067A", - "G194551A", - "A194656G", - "C194968-", - "G194969-", - "T194970-", - "T195901C", - "C196461T", - "G196580T", - "A196601-", - "A196602-", - "A196603-", - "A196604-", - "A196605-", - "A196606-", - "A196607-", - "A196608-", - "A196609-", - "A196610-", - "C196735T", - "A197082G" - ], - "OPG002": [ - "P170X", - "V171X", - "*350X" - ], - "OPG003": [ - "A189V", - "D489N" - ], - "OPG005": [ - "S3F" - ], - "OPG021": [ - "S219L" - ], - "OPG023": [ - "M109I", - "S258L", - "C304R", - "A426T", - "L602I" - ], - "OPG027": [ - "I47V", - "V126I" - ], - "OPG029": [ - "D153-", - "D154-" - ], - "OPG031": [ - "T80M", - "C241Y", - "G258-" - ], - "OPG037": [ - "C144Y" - ], - "OPG039": [ - "C279Y" - ], - "OPG044": [ - "V63A", - "T109A" - ], - "OPG047": [ - "D478N" - ], - "OPG049": [ - "R314X", - "H315X", - "*319X" - ], - "OPG050": [ - "F72X", - "*76X" - ], - "OPG065": [ - "A17T", - "H61N" - ], - "OPG068": [ - "P251S" - ], - "OPG070": [ - "H205Y" - ], - "OPG072": [ - "V10I" - ], - "OPG076": [ - "S20N" - ], - "OPG080": [ - "L521P", - "P582H" - ], - "OPG085": [ - "S79T" - ], - "OPG089": [ - "D303E" - ], - "OPG091": [ - "V62I", - "S73N" - ], - "OPG092": [ - "I244N" - ], - "OPG108": [ - "T111I" - ], - "OPG109": [ - "R364S", - "A630T" - ], - "OPG113": [ - "V537I" - ], - "OPG117": [ - "D454N" - ], - "OPG120": [ - "A19T" - ], - "OPG123": [ - "I172T", - "A313T", - "C436Y" - ], - "OPG125": [ - "E111D" - ], - "OPG130": [ - "A63V", - "L270I" - ], - "OPG133": [ - "F594S" - ], - "OPG134": [ - "E226D" - ], - "OPG136": [ - "A229T", - "D267N", - "F283Y" - ], - "OPG144": [ - "T184I" - ], - "OPG145": [ - "I249V" - ], - "OPG151": [ - "D6V", - "N282D" - ], - "OPG154": [ - "R74H" - ], - "OPG156": [ - "I261M" - ], - "OPG157": [ - "Q61X", - "H62X", - "*79X" - ], - "OPG159": [ - "N113X", - "N114-", - "N115-", - "Y116X", - "*146X" - ], - "OPG160": [ - "P2S" - ], - "OPG163": [ - "V46A" - ], - "OPG164": [ - "L227X", - "*229X" - ], - "OPG165": [ - "D106N" - ], - "OPG172": [ - "A125V" - ], - "OPG180": [ - "S554X", - "*560X" - ], - "OPG181": [ - "L85M", - "S127Y" - ], - "OPG188": [ - "V265I", - "S419R" - ], - "OPG189": [ - "K185R", - "R506H" - ], - "OPG191": [ - "P50Q", - "Y165X", - "F166X", - "*169X" - ], - "OPG192": [ - "G100E" - ], - "OPG197": [ - "M1I", - "N41X", - "*101X" - ], - "OPG200": [ - "E134G" - ], - "OPG205": [ - "R733Q" - ], - "OPG208": [ - "A34V", - "T300A" - ], - "OPG209": [ - "I11V", - "L21F" - ], - "OPG210": [ - "A98D", - "V173I", - "N334I", - "V515A", - "L733X", - "L734X", - "*1881X" - ] - }, - "labels": { - "aa": "OPG002: P170X, V171X, *350X; OPG003: A189V, D489N; OPG005: S3F; OPG021: S219L; OPG023: M109I, S258L, C304R, A426T, L602I; OPG027: I47V, V126I; OPG029: D153-, D154-; OPG031: T80M, C241Y, G258-; OPG037: C144Y; OPG039: C279Y; OPG044: V63A, T109A; OPG047: D478N; OPG049: R314X, H315X, *319X; OPG050: F72X, *76X; OPG065: A17T, H61N; OPG068: P251S; OPG070: H205Y; OPG072: V10I; OPG076: S20N; OPG080: L521P, P582H; OPG085: S79T; OPG089: D303E; OPG091: V62I, S73N; OPG092: I244N; OPG108: T111I; OPG109: R364S, A630T; OPG113: V537I; OPG117: D454N; OPG120: A19T; OPG123: I172T, A313T, C436Y; OPG125: E111D; OPG130: A63V, L270I; OPG133: F594S; OPG134: E226D; OPG136: A229T, D267N, F283Y; OPG144: T184I; OPG145: I249V; OPG151: D6V, N282D; OPG154: R74H; OPG156: I261M; OPG157: Q61X, H62X, *79X; OPG159: N113X, N114-, N115-, Y116X, *146X; OPG160: P2S; OPG163: V46A; OPG164: L227X, *229X; OPG165: D106N; OPG172: A125V; OPG180: S554X, *560X; OPG181: L85M, S127Y; OPG188: V265I, S419R; OPG189: K185R, R506H; OPG191: P50Q, Y165X, F166X, *169X; OPG192: G100E; OPG197: M1I, N41X, *101X; OPG200: E134G; OPG205: R733Q; OPG208: A34V, T300A; OPG209: I11V, L21F; OPG210: A98D, V173I, N334I, V515A, L733X, L734X, *1881X", - "clade": "clade I" - } - }, - "children": [ - { - "name": "DRC 07-0104", - "node_attrs": { - "div": 296, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2006-12-14" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 07-0104" - }, - "strain": { - "value": "JX878417" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A134C", - "T617-", - "C6615-", - "C13298T", - "A13302-", - "C13303-", - "C13304-", - "G13307-", - "A13308-", - "A13312T", - "A13313T", - "G13314T", - "C13316T", - "T13317A", - "G16147A", - "G23664T", - "T29805C", - "G31718A", - "C39731T", - "G47297T", - "C47929T", - "A49211G", - "C55169-", - "G59736A", - "A59910G", - "T70366C", - "T70958G", - "A71174-", - "C73040T", - "G87098T", - "C91509T", - "G91737A", - "C110159A", - "G117146A", - "G122405A", - "A142313G", - "C143414T", - "G143417-", - "A143418-", - "T143419-", - "C143420-", - "A143421-", - "T143422-", - "G143423-", - "A143424C", - "C143426A", - "C146214T", - "C148324A", - "T151060C", - "C159159T", - "C168295T", - "C169752T", - "A169769-", - "C169770-", - "A169771-", - "G169772-", - "A169773-", - "T169774-", - "G169775-", - "T169776-", - "A169777-", - "G169778-", - "A169779-", - "A169780-", - "G169781-", - "A169782-", - "T169783-", - "A169784-", - "T169785-", - "C169786-", - "A169787-", - "T169788-", - "G169789-", - "A169790-", - "A169791-", - "G169793-", - "A169794-", - "A169795G", - "A169796T", - "C175361T", - "A178925-", - "C178926-", - "-179226C", - "C179289T", - "T180737A", - "G181232A", - "G189594A", - "G191870A", - "A192419-", - "T197076G" - ], - "NBT03_gp175": [ - "A273T" - ], - "OPG039": [ - "P152Q" - ], - "OPG047": [ - "I464V" - ], - "OPG074": [ - "V653X", - "*666X" - ], - "OPG089": [ - "S365A" - ], - "OPG109": [ - "R784S" - ], - "OPG112": [ - "A88V" - ], - "OPG113": [ - "A3T" - ], - "OPG143": [ - "A304V" - ], - "OPG163": [ - "N38D" - ], - "OPG164": [ - "Q213X", - "D214-", - "H215-", - "E216X", - "H217N" - ], - "OPG170": [ - "G189R" - ], - "OPG197": [ - "T28I", - "T34-", - "D35-", - "V36-", - "E37-", - "D38-", - "I39-", - "M40-", - "X41-", - "E42X", - "I43L" - ], - "OPG204": [ - "T277M" - ], - "OPG209": [ - "S74T" - ] - }, - "labels": { - "aa": "NBT03_gp175: A273T; OPG039: P152Q; OPG047: I464V; OPG074: V653X, *666X; OPG089: S365A; OPG109: R784S; OPG112: A88V; OPG113: A3T; OPG143: A304V; OPG163: N38D; OPG164: Q213X, D214-, H215-, E216X, H217N; OPG170: G189R; OPG197: T28I, T34-, D35-, V36-, E37-, D38-, I39-, M40-, X41-, E42X, I43L; OPG204: T277M; OPG209: S74T" - } - } - }, - { - "name": "NODE_0000003", - "node_attrs": { - "div": 262, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A204C", - "G994A", - "G16141T", - "C72111T", - "-148336T", - "-169792C", - "G186944T", - "G188824A", - "C196216T", - "T197006G" - ], - "OPG027": [ - "F79L" - ], - "OPG197": [ - "X41N", - "X101*" - ], - "OPG210": [ - "E1863D" - ] - }, - "labels": { - "aa": "OPG027: F79L; OPG197: X41N, X101*; OPG210: E1863D" - } - }, - "children": [ - { - "name": "NODE_0000004", - "node_attrs": { - "div": 268, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G1861A", - "A4776-", - "A4777-", - "C4778-", - "T4779-", - "A4780-", - "A4781-", - "C4782-", - "T4783-", - "T4784-", - "A4785-", - "T4786-", - "G4787-", - "A4788-", - "C4789-", - "T4790-", - "T4791-", - "T6222-", - "T6223-", - "C6224-", - "T6225-", - "A6226-", - "T6275-", - "T6932-", - "G94890A", - "G105321T", - "C118612T", - "C121306T", - "C136539-", - "C136542-", - "A136546-", - "T136547-", - "C136548-", - "A136549-", - "T136550-", - "C136551-", - "A136552-", - "T136553-", - "C136554-", - "C136555-", - "A136556-", - "T136557-", - "C136558-", - "A136559-", - "T136560-", - "A144618G", - "-173295T", - "-173296A", - "-173297T", - "-173298A", - "-173299T", - "-173300A", - "-173301T", - "-173302A", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "T187040-", - "C195349T" - ], - "OPG136": [ - "A326T" - ], - "OPG153": [ - "M370-", - "M371-", - "D372-", - "D373-", - "D374-", - "D376X", - "D377X", - "*510X" - ] - }, - "labels": { - "aa": "OPG136: A326T; OPG153: M370-, M371-, D372-, D373-, D374-, D376X, D377X, *510X" - } - }, - "children": [ - { - "name": "KJ642618", - "node_attrs": { - "div": 298, - "author": { - "author": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Lil,Y., Weil,R.M., Muyembe,J.-J., Kingbeni,P.M., Balilo,M.", - "value": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Lil,Y., Weil,R.M., Muyembe,J.-J., Kingbeni,P.M., Balilo,M." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA" - }, - "date": { - "value": "1990-XX-XX" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "KJ642618" - }, - "strain": { - "value": "KJ642618" - }, - "country": { - "value": "Cameroon" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G2075A", - "A4350-", - "G4351-", - "A4352-", - "T4353-", - "G4354-", - "G4355-", - "A4356-", - "T4357-", - "T4358-", - "A4359-", - "A4360-", - "A4361-", - "T4362-", - "C4363-", - "G4364-", - "T4365-", - "G4366-", - "T4367-", - "A4368-", - "T4369-", - "T4370-", - "C4371-", - "A4372-", - "T4373-", - "C4374-", - "G4375-", - "T4376-", - "A4377-", - "T4378-", - "A4379-", - "G4380-", - "C4381-", - "A4382-", - "A4383-", - "T4384-", - "G4385-", - "T4386-", - "A4387-", - "A4388-", - "T4389-", - "G4390-", - "G4391-", - "A4392-", - "G4393-", - "A4394-", - "G4395-", - "T4396-", - "T4397-", - "A4398-", - "C4399-", - "C4400-", - "A4401-", - "C4402-", - "A4403-", - "T4404-", - "T4405-", - "T4406-", - "T4407-", - "A4408-", - "G4409-", - "T4410-", - "C4411-", - "G4412-", - "T4413-", - "T4414-", - "T4415-", - "A4416-", - "T4417-", - "T4418-", - "C4419-", - "A4420-", - "G4421-", - "A4422-", - "T4423-", - "C4424-", - "G4425-", - "C4426-", - "A4427-", - "G4428-", - "T4429-", - "G4430-", - "T4431-", - "T4432-", - "T4433-", - "A4434-", - "A4435-", - "T4436-", - "A4437-", - "A4438-", - "C4439-", - "T4440-", - "A4441-", - "A4442-", - "T4443-", - "T4444-", - "T4445-", - "A4446-", - "A4447-", - "A4448-", - "C4449-", - "A4450-", - "G4451-", - "A4452-", - "T4453-", - "G4454-", - "A4455-", - "G4456-", - "A4457-", - "T4458-", - "G4459-", - "A4460-", - "T4461-", - "A4462-", - "T4463-", - "A4464-", - "T4465-", - "C4466-", - "C4467-", - "A4468-", - "C4469-", - "A4470-", - "T4471-", - "C4472-", - "A4473-", - "A4474-", - "A4475-", - "G4476-", - "A4477-", - "A4478-", - "T4479-", - "G4480-", - "C4481-", - "G4482-", - "A4483-", - "G4484-", - "A4485-", - "T4486-", - "A4487-", - "C4488-", - "A4489-", - "T4490-", - "A4491-", - "T4492-", - "G4493-", - "A4494-", - "C4495-", - "A4496-", - "G4497-", - "A4498-", - "C4499-", - "A4500-", - "T4501-", - "T4502-", - "A4503-", - "T4504-", - "T4505-", - "G4506-", - "A4507-", - "C4508-", - "A4509-", - "G4510-", - "A4511-", - "A4512-", - "A4513-", - "T4514-", - "G4515-", - "T4516-", - "G4517-", - "A4518-", - "C4519-", - "C4520-", - "T4521-", - "T4522-", - "C4523-", - "A4524-", - "T4525-", - "T4526-", - "A4527-", - "T4528-", - "C4529-", - "A4530-", - "C4531-", - "C4532-", - "G4533-", - "T4534-", - "C4535-", - "G4536-", - "T4537-", - "C4538-", - "C4539-", - "A4540-", - "T4541-", - "A4542-", - "A4543-", - "A4544-", - "T4545-", - "G4546-", - "C4547-", - "G4548-", - "T4549-", - "T4550-", - "A4551-", - "G4552-", - "G4553-", - "T4554-", - "A4555-", - "C4556-", - "G4557-", - "T4558-", - "A4559-", - "C4560-", - "C4561-", - "A4562-", - "C4563-", - "A4564-", - "T4565-", - "A4566-", - "C4567-", - "T4568-", - "A4569-", - "T4570-", - "C4571-", - "G4572-", - "T4573-", - "T4574-", - "A4575-", - "A4576-", - "C4577-", - "G4578-", - "A4579-", - "T4580-", - "G4581-", - "C4582-", - "G4583-", - "C4584-", - "A4585-", - "C4586-", - "A4587-", - "A4588-", - "T4589-", - "C4590-", - "T4591-", - "C4592-", - "G4593-", - "T4594-", - "C4595-", - "C4596-", - "A4597-", - "T4598-", - "T4599-", - "T4600-", - "C4601-", - "A4602-", - "T4603-", - "C4604-", - "C4605-", - "A4606-", - "T4607-", - "C4608-", - "T4609-", - "T4610-", - "C4611-", - "A4612-", - "T4613-", - "A4614-", - "A4615-", - "T4616-", - "G4617-", - "A4618-", - "T4619-", - "T4620-", - "T4621-", - "A4622-", - "C4623-", - "T4624-", - "T4625-", - "T4626-", - "T4627-", - "T4628-", - "C4629-", - "A4630-", - "T4631-", - "A4632-", - "A4633-", - "T4634-", - "T4635-", - "A4636-", - "G4637-", - "A4638-", - "G4639-", - "A4640-", - "A4641-", - "A4642-", - "A4643-", - "A4644-", - "G4645-", - "A4646-", - "T4647-", - "C4648-", - "A4649-", - "A4650-", - "G4651-", - "G4652-", - "T4653-", - "A4654-", - "T4655-", - "A4656-", - "A4657-", - "A4658-", - "A4659-", - "A4660-", - "T4661-", - "T4662-", - "A4663-", - "G4664-", - "A4665-", - "A4666-", - "G4667-", - "T4668-", - "G4669-", - "T4670-", - "T4671-", - "A4672-", - "G4673-", - "A4674-", - "C4675-", - "T4676-", - "A4677-", - "T4678-", - "A4679-", - "A4680-", - "A4681-", - "C4682-", - "T4683-", - "A4684-", - "A4685-", - "C4686-", - "T4687-", - "T4688-", - "A4689-", - "T4690-", - "A4691-", - "A4692-", - "A4792-", - "A4793-", - "C4794-", - "T4795-", - "A4796-", - "A4797-", - "C4798-", - "T4799-", - "T4800-", - "A4801-", - "T4802-", - "G4803-", - "A4804-", - "C4805-", - "T4806-", - "A4807-", - "T4808-", - "T4809-", - "A4810-", - "A4811-", - "C4812-", - "T4813-", - "C4814-", - "A4815-", - "T4816-", - "T4817-", - "T4818-", - "C4819-", - "A4820-", - "A4821-", - "G4822-", - "A4823-", - "A4824-", - "A4825-", - "G4826-", - "G4827-", - "T4828-", - "G4829-", - "G4830-", - "G4831-", - "T4832-", - "G4833-", - "G4834-", - "A4835-", - "G4836-", - "A4837-", - "G4838-", - "A4839-", - "A4840-", - "C4841-", - "T4842-", - "C4843-", - "T4844-", - "A4845-", - "T4846-", - "A4847-", - "T4848-", - "G4849-", - "A4850-", - "C4851-", - "A4852-", - "G4853-", - "C4854-", - "T4855-", - "T4856-", - "G4857-", - "T4858-", - "G4859-", - "A4860-", - "A4861-", - "A4862-", - "C4863-", - "A4864-", - "A4865-", - "T4866-", - "T4867-", - "A4868-", - "G4869-", - "A4870-", - "T4871-", - "C4872-", - "C4873-", - "C4874-", - "T4875-", - "A4876-", - "A4877-", - "T4878-", - "T4879-", - "T4880-", - "C4881-", - "T4882-", - "A4883-", - "A4884-", - "T4885-", - "G4886-", - "G4887-", - "A4888-", - "A4889-", - "G4890-", - "T4891-", - "T4892-", - "T4893-", - "T4894-", - "G4895-", - "A4896-", - "T4897-", - "A4898-", - "G4899-", - "G4900-", - "A4901-", - "G4902-", - "A4903-", - "T4904-", - "T4905-", - "G4906-", - "T4907-", - "C4908-", - "A4909-", - "T4910-", - "C4911-", - "A4912-", - "G4913-", - "T4914-", - "T4915-", - "G4916-", - "A4917-", - "T4918-", - "A4919-", - "C4920-", - "A4921-", - "T4922-", - "T4923-", - "G4924-", - "T4925-", - "T4926-", - "T4927-", - "A4928-", - "T4929-", - "T4930-", - "A4931-", - "T4932-", - "C4933-", - "T4934-", - "C4935-", - "A4936-", - "T4937-", - "C4938-", - "T4939-", - "A4940-", - "T4941-", - "T4942-", - "A4943-", - "G4944-", - "A4945-", - "G4946-", - "C4947-", - "A4948-", - "C4949-", - "G4950-", - "T4951-", - "C4952-", - "T4953-", - "G4954-", - "T4955-", - "T4956-", - "T4957-", - "A4958-", - "G4959-", - "A4960-", - "G4961-", - "C4962-", - "T4963-", - "T4964-", - "T4965-", - "A4966-", - "G4967-", - "T4968-", - "G4969-", - "A4970-", - "C4971-", - "C4972-", - "T4973-", - "G4974-", - "C4975-", - "T4976-", - "C4977-", - "G4978-", - "G4979-", - "T4980-", - "T4981-", - "A4982-", - "C4983-", - "T4984-", - "T4985-", - "C4986-", - "T4987-", - "G4988-", - "T4989-", - "G4990-", - "T4991-", - "A4992-", - "A4993-", - "A4994-", - "T4995-", - "C4996-", - "T4997-", - "T4998-", - "G4999-", - "A5000-", - "A5001-", - "T5002-", - "C5003-", - "C5004-", - "T5005-", - "T5006-", - "T5007-", - "A5008-", - "G5009-", - "T5010-", - "G5011-", - "A5012-", - "T5013-", - "A5014-", - "C5015-", - "A5016-", - "C5017-", - "T5018-", - "G5019-", - "T5020-", - "G5021-", - "T5022-", - "C5023-", - "A5024-", - "A5025-", - "A5026-", - "A5027-", - "C5028-", - "T5029-", - "G5030-", - "G5031-", - "A5032-", - "T5033-", - "G5034-", - "T5035-", - "T5036-", - "T5037-", - "A5038-", - "G5039-", - "A5040-", - "A5041-", - "T5042-", - "A5043-", - "C5044-", - "C5045-", - "T5046-", - "A5047-", - "T5048-", - "G5049-", - "T5050-", - "A5051-", - "G5052-", - "A5053-", - "A5054-", - "T5055-", - "A5056-", - "T5057-", - "G5058-", - "G5059-", - "G5060-", - "A5061-", - "A5062-", - "G5063-", - "C5064-", - "A5065-", - "T5066-", - "G5067-", - "C5068-", - "T5069-", - "T5070-", - "G5071-", - "T5072-", - "T5073-", - "T5074-", - "T5075-", - "T5076-", - "G5077-", - "T5078-", - "C5079-", - "T5080-", - "C5081-", - "T5082-", - "A5083-", - "T5084-", - "T5085-", - "A5086-", - "T5087-", - "A5088-", - "G5089-", - "A5090-", - "T5091-", - "T5092-", - "A5093-", - "A5094-", - "C5095-", - "T5096-", - "C5097-", - "A5098-", - "T5099-", - "A5100-", - "C5101-", - "A5102-", - "T5103-", - "G5104-", - "G5105-", - "T5106-", - "T5107-", - "G5108-", - "T5109-", - "A5110-", - "T5111-", - "T5112-", - "A5113-", - "T5114-", - "G5115-", - "A5116-", - "A5117-", - "T5118-", - "T5119-", - "T5120-", - "T5121-", - "C5122-", - "A5123-", - "T5124-", - "C5125-", - "T5126-", - "G5127-", - "C5128-", - "C5129-", - "T5130-", - "A5131-", - "A5132-", - "T5133-", - "G5134-", - "T5135-", - "A5136-", - "C5137-", - "T5138-", - "C5139-", - "C5140-", - "A5141-", - "A5142-", - "T5143-", - "T5144-", - "C5145-", - "T5146-", - "T5147-", - "G5148-", - "T5149-", - "T5150-", - "T5151-", - "A5152-", - "C5153-", - "A5154-", - "A5155-", - "T5156-", - "C5157-", - "A5158-", - "A5159-", - "T5160-", - "T5161-", - "A5162-", - "T5163-", - "A5164-", - "T5165-", - "A5166-", - "A5167-", - "T5168-", - "C5169-", - "A5170-", - "A5171-", - "A5172-", - "G5173-", - "A5174-", - "G5175-", - "T5176-", - "G5177-", - "A5178-", - "T5179-", - "G5180-", - "A5181-", - "T5182-", - "G5183-", - "C5184-", - "A5185-", - "T5186-", - "A5187-", - "C5188-", - "A5189-", - "C5190-", - "A5191-", - "T5192-", - "T5193-", - "A5194-", - "C5195-", - "A5196-", - "A5197-", - "A5198-", - "G5199-", - "T5200-", - "G5201-", - "A5202-", - "A5203-", - "T5204-", - "A5205-", - "A5206-", - "T5207-", - "C5208-", - "T5209-", - "A5210-", - "C5211-", - "C5212-", - "A5213-", - "T5214-", - "C5215-", - "A5216-", - "T5217-", - "A5218-", - "A5219-", - "A5220-", - "A5221-", - "T5222-", - "A5223-", - "C5224-", - "T5225-", - "T5226-", - "G5227-", - "A5228-", - "T5229-", - "A5230-", - "C5231-", - "A5232-", - "G5233-", - "A5234-", - "G5235-", - "C5236-", - "T5237-", - "T5238-", - "T5239-", - "A5240-", - "T5241-", - "C5242-", - "A5243-", - "C5244-", - "A5245-", - "T5246-", - "C5247-", - "A5248-", - "T5249-", - "G5250-", - "G5251-", - "T5252-", - "T5253-", - "T5254-", - "T5255-", - "C5256-", - "A5257-", - "A5258-", - "T5259-", - "T5260-", - "G5261-", - "T5262-", - "A5263-", - "T5264-", - "T5265-", - "A5266-", - "T5267-", - "T5268-", - "A5269-", - "A5270-", - "G5271-", - "T5272-", - "A5273-", - "T5274-", - "A5275-", - "G5276-", - "C5277-", - "T5278-", - "A5279-", - "A5280-", - "T5281-", - "T5282-", - "T5283-", - "T5284-", - "A5285-", - "T5286-", - "A5287-", - "C5288-", - "A5289-", - "G5290-", - "T5291-", - "C5292-", - "A5293-", - "A5294-", - "T5295-", - "A5296-", - "G5297-", - "A5298-", - "C5299-", - "A5300-", - "A5301-", - "T5302-", - "G5303-", - "G5304-", - "T5305-", - "T5306-", - "C5307-", - "T5308-", - "C5309-", - "T5310-", - "A5311-", - "A5312-", - "G5313-", - "C5314-", - "A5315-", - "A5316-", - "T5317-", - "A5318-", - "T5319-", - "T5320-", - "T5321-", - "C5322-", - "T5323-", - "A5324-", - "A5325-", - "T5326-", - "A5327-", - "T5328-", - "T5329-", - "T5330-", - "T5331-", - "A5332-", - "A5333-", - "G5334-", - "A5335-", - "T5336-", - "G5337-", - "T5338-", - "G5339-", - "C5340-", - "T5341-", - "T5342-", - "C5343-", - "C5344-", - "C5345-", - "T5346-", - "A5347-", - "C5348-", - "G5349-", - "G5350-", - "G5351-", - "C5352-", - "G5353-", - "A5354-", - "T5355-", - "G5356-", - "A5357-", - "C5358-", - "A5359-", - "G5360-", - "A5361-", - "T5362-", - "C5363-", - "C5364-", - "C5365-", - "C5366-", - "T5367-", - "A5368-", - "T5369-", - "C5370-", - "C5371-", - "A5372-", - "C5373-", - "G5374-", - "G5375-", - "C5376-", - "C5377-", - "A5378-", - "C5379-", - "G5380-", - "T5381-", - "C5382-", - "A5383-", - "A5384-", - "G5385-", - "A5386-", - "C5387-", - "A5388-", - "T5389-", - "G5390-", - "T5391-", - "A5392-", - "T5393-", - "A5394-", - "T5395-", - "C5396-", - "C5397-", - "A5398-", - "T5399-", - "T5400-", - "A5401-", - "C5402-", - "T5403-", - "C5404-", - "A5405-", - "T5406-", - "T5407-", - "A5408-", - "C5409-", - "T5410-", - "G5411-", - "C5412-", - "G5413-", - "T5414-", - "T5415-", - "G5416-", - "A5417-", - "C5418-", - "A5419-", - "T5420-", - "T5421-", - "T5422-", - "G5423-", - "C5424-", - "T5425-", - "C5426-", - "C5427-", - "A5428-", - "T5429-", - "T5430-", - "T5431-", - "T5432-", - "C5433-", - "T5434-", - "A5435-", - "A5436-", - "T5437-", - "A5438-", - "G5439-", - "C5440-", - "C5441-", - "A5442-", - "T5443-", - "G5444-", - "A5445-", - "T5446-", - "A5447-", - "C5448-", - "T5449-", - "A5450-", - "A5451-", - "A5452-", - "T5453-", - "C5454-", - "T5455-", - "A5456-", - "T5457-", - "A5458-", - "T5459-", - "A5460-", - "A5461-", - "C5462-", - "C5463-", - "T5464-", - "G5465-", - "C5466-", - "A5467-", - "T5468-", - "A5469-", - "G5470-", - "A5471-", - "T5472-", - "A5473-", - "G5474-", - "C5475-", - "G5476-", - "C5477-", - "G5478-", - "A5479-", - "T5480-", - "A5481-", - "A5482-", - "A5483-", - "G5484-", - "C5485-", - "A5486-", - "A5487-", - "G5488-", - "G5489-", - "T5490-", - "C5491-", - "C5492-", - "T5493-", - "T5494-", - "C5495-", - "C5496-", - "A5497-", - "C5498-", - "C5499-", - "A5500-", - "G5501-", - "C5502-", - "A5503-", - "T5504-", - "C5505-", - "T5506-", - "A5507-", - "G5508-", - "T5509-", - "T5510-", - "G5511-", - "A5512-", - "T5513-", - "T5514-", - "G5515-", - "A5516-", - "T5517-", - "A5518-", - "T5519-", - "C5520-", - "T5521-", - "T5522-", - "C5523-", - "A5524-", - "A5525-", - "T5526-", - "A5527-", - "T5528-", - "A5529-", - "T5530-", - "G5531-", - "G5532-", - "G5533-", - "A5534-", - "T5535-", - "A5536-", - "C5537-", - "A5538-", - "A5539-", - "A5540-", - "G5541-", - "C5542-", - "T5543-", - "T5544-", - "A5545-", - "T5546-", - "A5547-", - "A5548-", - "A5549-", - "T5550-", - "T5551-", - "T5552-", - "C5553-", - "T5554-", - "A5555-", - "A5556-", - "T5557-", - "A5558-", - "C5559-", - "T5560-", - "G5561-", - "T5562-", - "G5563-", - "G5564-", - "G5565-", - "T5566-", - "T5567-", - "C5568-", - "A5569-", - "T5570-", - "C5571-", - "T5572-", - "A5573-", - "C5574-", - "A5575-", - "A5576-", - "G5577-", - "G5578-", - "A5579-", - "A5580-", - "T5581-", - "C5582-", - "C5583-", - "C5584-", - "C5585-", - "T5586-", - "A5587-", - "G5588-", - "T5589-", - "A5590-", - "T5591-", - "A5592-", - "C5593-", - "T5594-", - "G5595-", - "A5596-", - "A5597-", - "T5598-", - "T5599-", - "A5600-", - "T5601-", - "T5602-", - "T5603-", - "T5604-", - "A5605-", - "T5606-", - "A5607-", - "T5608-", - "A5609-", - "G5610-", - "A5611-", - "T5612-", - "C5613-", - "T5614-", - "A5615-", - "A5616-", - "T5617-", - "T5618-", - "T5619-", - "A5620-", - "A5621-", - "C5622-", - "A5623-", - "T5624-", - "C5625-", - "A5626-", - "T5627-", - "T5628-", - "T5629-", - "T5630-", - "C5631-", - "A5632-", - "T5633-", - "C5634-", - "T5635-", - "G5636-", - "G5637-", - "G5638-", - "A5639-", - "T5640-", - "A5641-", - "C5642-", - "C5643-", - "A5644-", - "C5645-", - "A5646-", - "A5647-", - "T5648-", - "T5649-", - "C5650-", - "A5651-", - "A5652-", - "A5653-", - "A5654-", - "T5655-", - "A5656-", - "A5657-", - "A5658-", - "C5659-", - "T5660-", - "C5661-", - "A5662-", - "A5663-", - "C5664-", - "A5665-", - "A5666-", - "C5667-", - "A5668-", - "C5669-", - "T5670-", - "A5671-", - "C5672-", - "T5673-", - "T5674-", - "T5675-", - "C5676-", - "C5677-", - "T5678-", - "T5679-", - "T5680-", - "T5681-", - "T5682-", - "A5683-", - "C5684-", - "A5685-", - "T5686-", - "A5687-", - "T5688-", - "T5689-", - "C5690-", - "C5691-", - "C5692-", - "C5693-", - "T5694-", - "A5695-", - "A5696-", - "A5697-", - "A5698-", - "T5699-", - "A5700-", - "G5701-", - "G5702-", - "C5703-", - "A5704-", - "T5705-", - "T5706-", - "C5707-", - "A5708-", - "A5709-", - "G5710-", - "C5711-", - "A5712-", - "T5713-", - "T5714-", - "C5715-", - "T5716-", - "A5717-", - "T5718-", - "T5719-", - "T5720-", - "T5721-", - "A5722-", - "T5723-", - "A5724-", - "T5725-", - "A5726-", - "T5727-", - "T5728-", - "A5729-", - "C5730-", - "A5731-", - "G5732-", - "C5733-", - "C5734-", - "C5735-", - "C5736-", - "A5737-", - "T5738-", - "G5739-", - "A5740-", - "T5741-", - "C5742-", - "T5743-", - "A5744-", - "C5745-", - "C5746-", - "A5747-", - "T5748-", - "A5749-", - "A5750-", - "A5751-", - "A5752-", - "T5753-", - "C5754-", - "A5755-", - "A5756-", - "C5757-", - "A5758-", - "A5759-", - "T5760-", - "G5761-", - "T5762-", - "C5763-", - "T5764-", - "A5765-", - "T5766-", - "T5767-", - "T5768-", - "C5769-", - "T5770-", - "A5771-", - "C5772-", - "A5773-", - "T5774-", - "A5775-", - "T5776-", - "G5777-", - "C5778-", - "A5779-", - "T5780-", - "T5781-", - "A5782-", - "G5783-", - "A5784-", - "T5785-", - "A5786-", - "G5787-", - "A5788-", - "T5789-", - "A5790-", - "G5791-", - "T5792-", - "A5793-", - "A5794-", - "A5795-", - "G5796-", - "T5797-", - "A5798-", - "A5799-", - "G5800-", - "A5801-", - "G5802-", - "A5803-", - "T5804-", - "C5805-", - "T5806-", - "T5807-", - "G5808-", - "T5809-", - "A5810-", - "C5811-", - "A5812-", - "G5813-", - "A5814-", - "A5815-", - "T5816-", - "T5817-", - "A5818-", - "C5819-", - "A5820-", - "A5821-", - "T5822-", - "T5823-", - "C5824-", - "T5825-", - "T5826-", - "A5827-", - "A5828-", - "T5829-", - "A5830-", - "A5831-", - "T5832-", - "T5833-", - "A5834-", - "T5835-", - "A5836-", - "G5837-", - "A5838-", - "G5839-", - "A5840-", - "A5841-", - "A5842-", - "A5843-", - "T5844-", - "A5845-", - "T5846-", - "C5847-", - "T5848-", - "T5849-", - "C5850-", - "C5851-", - "A5852-", - "T5853-", - "A5854-", - "T5855-", - "A5856-", - "A5857-", - "T5858-", - "T5859-", - "C5860-", - "T5861-", - "T5862-", - "T5863-", - "G5864-", - "A5865-", - "C5866-", - "A5867-", - "C5868-", - "T5869-", - "A5870-", - "A5871-", - "T5872-", - "G5873-", - "C5874-", - "A5875-", - "G5876-", - "A5877-", - "T5878-", - "A5879-", - "T5880-", - "A5881-", - "A5882-", - "T5883-", - "A5884-", - "T5885-", - "C5886-", - "T5887-", - "T5888-", - "T5889-", - "A5890-", - "T5891-", - "A5892-", - "T5893-", - "G5894-", - "T5895-", - "A5896-", - "A5897-", - "T5898-", - "A5899-", - "T5900-", - "A5901-", - "T5902-", - "G5903-", - "C5904-", - "A5905-", - "A5906-", - "A5907-", - "C5908-", - "A5909-", - "G5910-", - "T5911-", - "C5912-", - "T5913-", - "A5914-", - "T5915-", - "C5916-", - "T5917-", - "A5918-", - "C5919-", - "T5920-", - "A5921-", - "T5922-", - "A5923-", - "T5924-", - "A5925-", - "C5926-", - "T5927-", - "G5928-", - "A5929-", - "T5930-", - "C5931-", - "A5932-", - "A5933-", - "T5934-", - "A5935-", - "T5936-", - "T5937-", - "A5938-", - "T5939-", - "C5940-", - "T5941-", - "C5942-", - "T5943-", - "A5944-", - "T5945-", - "G5946-", - "A5947-", - "A5948-", - "T5949-", - "C5950-", - "C5951-", - "T5952-", - "A5953-", - "A5954-", - "A5955-", - "A5956-", - "T5957-", - "A5958-", - "A5959-", - "T5960-", - "C5961-", - "A5962-", - "T5963-", - "A5964-", - "C5965-", - "A5966-", - "G5967-", - "A5968-", - "A5969-", - "C5970-", - "A5971-", - "T5972-", - "C5973-", - "T5974-", - "A5975-", - "C5976-", - "A5977-", - "G5978-", - "G5979-", - "A5980-", - "T5981-", - "C5982-", - "A5983-", - "C5984-", - "A5985-", - "A5986-", - "A5987-", - "T5988-", - "T5989-", - "G5990-", - "G5991-", - "T5992-", - "T5993-", - "C5994-", - "A5995-", - "A5996-", - "G5997-", - "G5998-", - "A5999-", - "G6000-", - "A6001-", - "A6002-", - "A6003-", - "T6004-", - "C6005-", - "T6006-", - "A6007-", - "T6008-", - "C6009-", - "A6010-", - "A6011-", - "A6012-", - "T6013-", - "A6014-", - "T6015-", - "T6016-", - "T6017-", - "T6018-", - "C6019-", - "C6020-", - "T6021-", - "G6022-", - "T6023-", - "C6024-", - "A6025-", - "A6026-", - "C6027-", - "A6028-", - "A6029-", - "C6030-", - "T6031-", - "G6032-", - "G6033-", - "T6034-", - "T6035-", - "C6036-", - "T6037-", - "A6038-", - "G6039-", - "A6040-", - "A6041-", - "C6042-", - "A6043-", - "T6044-", - "A6045-", - "A6046-", - "C6047-", - "A6048-", - "G6049-", - "T6050-", - "C6051-", - "A6052-", - "A6053-", - "C6054-", - "A6055-", - "C6056-", - "C6057-", - "T6058-", - "A6059-", - "A6060-", - "T6061-", - "C6062-", - "C6063-", - "A6064-", - "T6065-", - "G6066-", - "T6067-", - "T6068-", - "T6069-", - "T6070-", - "T6071-", - "T6072-", - "A6073-", - "T6074-", - "A6075-", - "G6076-", - "T6077-", - "C6078-", - "A6079-", - "T6080-", - "C6081-", - "T6082-", - "A6083-", - "C6084-", - "C6085-", - "A6086-", - "A6087-", - "A6088-", - "G6089-", - "A6090-", - "T6091-", - "A6092-", - "A6093-", - "T6094-", - "G6095-", - "A6096-", - "C6097-", - "C6098-", - "A6099-", - "A6100-", - "A6101-", - "G6102-", - "A6103-", - "T6104-", - "C6105-", - "G6106-", - "A6107-", - "G6108-", - "G6109-", - "T6110-", - "C6111-", - "G6112-", - "T6113-", - "C6114-", - "G6115-", - "T6116-", - "G6117-", - "A6118-", - "A6119-", - "A6120-", - "C6121-", - "T6122-", - "G6123-", - "C6124-", - "T6125-", - "C6126-", - "A6127-", - "T6128-", - "C6129-", - "G6130-", - "A6131-", - "C6132-", - "A6133-", - "G6134-", - "C6135-", - "C6136-", - "A6137-", - "T6138-", - "G6139-", - "A6140-", - "A6141-", - "A6142-", - "T6143-", - "C6144-", - "T6145-", - "G6146-", - "C6147-", - "C6148-", - "G6149-", - "A6150-", - "C6151-", - "T6152-", - "C6153-", - "C6154-", - "A6155-", - "T6156-", - "G6157-", - "G6158-", - "C6159-", - "G6160-", - "C6161-", - "G6162-", - "A6163-", - "A6164-", - "T6165-", - "C6166-", - "G6167-", - "C6168-", - "A6169-", - "C6170-", - "T6171-", - "G6172-", - "T6173-", - "C6174-", - "T6175-", - "T6176-", - "A6177-", - "T6178-", - "T6179-", - "C6180-", - "G6181-", - "C6182-", - "C6183-", - "A6184-", - "T6185-", - "T6186-", - "G6187-", - "A6188-", - "T6189-", - "T6190-", - "T6191-", - "T6192-", - "C6193-", - "A6194-", - "T6195-", - "T6196-", - "T6197-", - "T6198-", - "T6199-", - "T6200-", - "A6201-", - "T6202-", - "A6203-", - "A6204-", - "T6205-", - "T6206-", - "A6207-", - "T6208-", - "G6209-", - "T6210-", - "A6211-", - "C6212-", - "A6213-", - "T6214-", - "G6215-", - "T6216-", - "T6217-", - "T6218-", - "T6219-", - "C6220-", - "C6221-", - "T6227-", - "T6228-", - "C6229-", - "T6230-", - "C6231-", - "A6232-", - "A6233-", - "G6234-", - "A6235-", - "G6236-", - "T6237-", - "C6238-", - "T6239-", - "A6240-", - "C6241-", - "A6242-", - "A6243-", - "A6244-", - "A6245-", - "A6246-", - "T6247-", - "A6248-", - "T6249-", - "A6250-", - "T6251-", - "T6252-", - "T6253-", - "T6254-", - "T6255-", - "T6256-", - "C6257-", - "G6258-", - "A6259-", - "T6260-", - "A6261-", - "T6262-", - "C6263-", - "T6264-", - "A6265-", - "A6266-", - "G6267-", - "T6268-", - "A6269-", - "C6270-", - "T6271-", - "A6272-", - "A6273-", - "G6274-", - "T6276-", - "T6277-", - "T6278-", - "T6279-", - "T6280-", - "T6281-", - "A6282-", - "C6283-", - "T6284-", - "G6285-", - "T6286-", - "T6287-", - "T6288-", - "T6289-", - "T6290-", - "G6291-", - "T6292-", - "T6293-", - "A6294-", - "C6295-", - "T6296-", - "G6297-", - "T6298-", - "C6299-", - "T6300-", - "T6301-", - "C6302-", - "C6303-", - "A6304-", - "T6305-", - "T6306-", - "C6307-", - "T6308-", - "T6309-", - "C6310-", - "T6311-", - "A6312-", - "A6313-", - "C6314-", - "T6315-", - "A6316-", - "A6317-", - "A6318-", - "G6319-", - "A6320-", - "T6321-", - "C6322-", - "T6323-", - "G6324-", - "A6325-", - "G6326-", - "A6327-", - "T6328-", - "A6329-", - "A6330-", - "A6331-", - "T6332-", - "T6333-", - "A6334-", - "T6335-", - "A6336-", - "C6337-", - "A6338-", - "A6339-", - "T6340-", - "C6341-", - "T6342-", - "T6343-", - "C6344-", - "G6345-", - "C6346-", - "T6347-", - "A6348-", - "T6349-", - "C6350-", - "G6351-", - "A6352-", - "A6353-", - "C6354-", - "C6355-", - "A6356-", - "T6357-", - "T6358-", - "T6359-", - "T6360-", - "T6361-", - "G6362-", - "T6363-", - "A6364-", - "G6365-", - "T6366-", - "C6367-", - "T6368-", - "A6369-", - "A6370-", - "A6371-", - "G6372-", - "C6373-", - "C6374-", - "T6375-", - "G6376-", - "A6377-", - "A6378-", - "G6379-", - "T6380-", - "A6381-", - "A6382-", - "T6383-", - "T6384-", - "A6385-", - "A6386-", - "C6387-", - "C6388-", - "A6389-", - "A6390-", - "C6391-", - "T6392-", - "G6393-", - "T6394-", - "T6395-", - "T6396-", - "T6397-", - "T6398-", - "A6399-", - "T6400-", - "T6401-", - "A6402-", - "G6403-", - "T6404-", - "G6405-", - "G6406-", - "C6407-", - "T6408-", - "T6409-", - "T6410-", - "T6411-", - "T6412-", - "T6413-", - "C6414-", - "G6415-", - "A6416-", - "T6417-", - "C6418-", - "T6419-", - "A6420-", - "T6421-", - "C6422-", - "C6423-", - "T6424-", - "C6425-", - "G6426-", - "T6427-", - "C6428-", - "C6431-", - "T6432-", - "C6433-", - "A6434-", - "T6435-", - "C6436-", - "A6437-", - "T6438-", - "C6439-", - "C6440-", - "T6441-", - "T6442-", - "A6443-", - "T6444-", - "A6445-", - "T6446-", - "T6447-", - "A6448-", - "T6449-", - "T6450-", - "A6451-", - "T6452-", - "C6453-", - "A6454-", - "T6455-", - "T6456-", - "A6457-", - "T6458-", - "T6459-", - "A6460-", - "T6461-", - "C6462-", - "A6463-", - "T6464-", - "A6465-", - "G6466-", - "T6467-", - "C6468-", - "T6469-", - "A6470-", - "T6471-", - "T6472-", - "A6473-", - "A6474-", - "A6475-", - "C6476-", - "A6477-", - "C6478-", - "A6479-", - "A6480-", - "A6481-", - "T6482-", - "C6483-", - "A6484-", - "T6485-", - "C6486-", - "T6487-", - "A6488-", - "C6489-", - "G6490-", - "T6491-", - "T6492-", - "T6493-", - "A6494-", - "T6495-", - "A6496-", - "A6497-", - "C6498-", - "A6499-", - "A6500-", - "C6501-", - "A6502-", - "T6503-", - "T6504-", - "C6505-", - "T6506-", - "C6507-", - "A6508-", - "T6509-", - "T6510-", - "A6511-", - "T6512-", - "T6513-", - "A6514-", - "A6515-", - "T6516-", - "T6517-", - "A6518-", - "G6519-", - "T6520-", - "T6521-", - "C6522-", - "T6523-", - "G6524-", - "T6525-", - "A6526-", - "G6527-", - "A6528-", - "A6529-", - "T6530-", - "A6531-", - "T6532-", - "C6533-", - "T6534-", - "T6535-", - "T6536-", - "A6537-", - "A6538-", - "T6539-", - "A6540-", - "A6541-", - "T6542-", - "T6543-", - "T6544-", - "G6545-", - "G6546-", - "C6547-", - "T6548-", - "A6549-", - "T6550-", - "A6551-", - "C6552-", - "A6553-", - "T6554-", - "C6555-", - "T6556-", - "G6557-", - "T6558-", - "T6559-", - "C6560-", - "A6561-", - "A6562-", - "T6563-", - "A6564-", - "C6565-", - "T6566-", - "A6567-", - "T6568-", - "C6569-", - "T6570-", - "A6571-", - "T6572-", - "T6573-", - "G6574-", - "A6575-", - "T6576-", - "G6577-", - "A6578-", - "T6579-", - "T6580-", - "T6581-", - "C6582-", - "T6583-", - "T6584-", - "T6585-", - "T6586-", - "T6587-", - "T6588-", - "A6589-", - "A6590-", - "G6591-", - "A6592-", - "C6593-", - "T6594-", - "T6595-", - "A6596-", - "A6597-", - "A6598-", - "C6599-", - "T6600-", - "A6601-", - "G6602-", - "T6603-", - "T6604-", - "A6605-", - "T6606-", - "G6607-", - "G6608-", - "T6609-", - "A6610-", - "A6611-", - "T6612-", - "G6613-", - "A6614-", - "C6615-", - "G6616-", - "A6617-", - "T6618-", - "G6619-", - "A6620-", - "A6621-", - "A6622-", - "T6623-", - "C6624-", - "G6625-", - "A6626-", - "G6627-", - "T6628-", - "A6629-", - "G6630-", - "T6631-", - "A6632-", - "A6633-", - "C6634-", - "T6635-", - "T6636-", - "C6637-", - "T6638-", - "A6639-", - "A6640-", - "T6641-", - "A6642-", - "A6643-", - "A6644-", - "G6645-", - "A6646-", - "C6647-", - "T6648-", - "T6649-", - "G6650-", - "A6651-", - "T6652-", - "A6653-", - "T6654-", - "C6655-", - "A6656-", - "T6657-", - "T6658-", - "A6659-", - "T6660-", - "C6661-", - "A6662-", - "T6663-", - "A6664-", - "T6665-", - "G6666-", - "T6667-", - "T6668-", - "T6669-", - "G6670-", - "A6671-", - "T6672-", - "C6673-", - "G6674-", - "T6675-", - "C6676-", - "A6677-", - "T6678-", - "A6679-", - "G6680-", - "T6681-", - "T6682-", - "A6683-", - "A6684-", - "T6685-", - "A6686-", - "G6687-", - "T6688-", - "G6689-", - "T6690-", - "G6691-", - "G6692-", - "C6693-", - "T6694-", - "A6695-", - "A6696-", - "A6697-", - "T6698-", - "G6699-", - "G6700-", - "T6701-", - "A6702-", - "C6703-", - "T6704-", - "G6705-", - "T6706-", - "T6707-", - "A6708-", - "A6709-", - "T6710-", - "A6711-", - "A6712-", - "G6713-", - "T6714-", - "T6715-", - "T6716-", - "A6717-", - "T6718-", - "A6719-", - "G6720-", - "A6721-", - "C6722-", - "A6723-", - "A6724-", - "T6725-", - "A6726-", - "T6727-", - "C6728-", - "A6729-", - "T6730-", - "A6731-", - "G6732-", - "T6733-", - "A6734-", - "T6735-", - "T6736-", - "T6737-", - "T6738-", - "C6739-", - "T6740-", - "T6741-", - "T6742-", - "C6743-", - "C6744-", - "A6745-", - "G6746-", - "A6747-", - "A6748-", - "T6749-", - "T6750-", - "A6751-", - "G6752-", - "A6753-", - "T6754-", - "T6755-", - "A6756-", - "T6757-", - "T6758-", - "T6759-", - "T6760-", - "T6761-", - "T6762-", - "T6763-", - "A6764-", - "A6765-", - "A6766-", - "T6767-", - "A6768-", - "C6769-", - "T6770-", - "G6771-", - "A6772-", - "T6773-", - "C6774-", - "C6775-", - "T6776-", - "C6777-", - "A6778-", - "C6779-", - "A6780-", - "A6781-", - "T6782-", - "T6783-", - "C6784-", - "C6785-", - "G6786-", - "T6787-", - "G6788-", - "A6789-", - "T6790-", - "G6791-", - "T6792-", - "A6793-", - "G6794-", - "C6795-", - "A6796-", - "G6797-", - "T6798-", - "A6799-", - "G6800-", - "T6801-", - "T6802-", - "G6803-", - "G6804-", - "T6805-", - "G6806-", - "C6807-", - "A6808-", - "T6809-", - "G6810-", - "G6811-", - "T6812-", - "C6813-", - "T6814-", - "A6815-", - "T6816-", - "A6817-", - "T6818-", - "C6819-", - "G6820-", - "T6821-", - "T6822-", - "A6823-", - "A6824-", - "A6825-", - "A6826-", - "T6827-", - "G6828-", - "T6829-", - "A6830-", - "T6831-", - "C6832-", - "A6833-", - "T6834-", - "A6835-", - "T6836-", - "A6837-", - "T6838-", - "A6839-", - "A6840-", - "T6841-", - "A6842-", - "G6843-", - "T6844-", - "T6845-", - "T6846-", - "T6847-", - "C6848-", - "T6849-", - "G6850-", - "A6851-", - "C6852-", - "G6853-", - "T6854-", - "G6855-", - "G6856-", - "A6857-", - "G6858-", - "T6859-", - "A6860-", - "C6861-", - "A6862-", - "G6863-", - "A6864-", - "A6865-", - "T6866-", - "T6867-", - "T6868-", - "T6869-", - "C6870-", - "G6871-", - "A6872-", - "T6873-", - "T6874-", - "A6875-", - "A6876-", - "T6877-", - "G6878-", - "A6879-", - "G6880-", - "T6881-", - "T6882-", - "C6883-", - "A6884-", - "T6885-", - "G6886-", - "G6887-", - "T6888-", - "A6889-", - "A6890-", - "G6891-", - "G6892-", - "A6893-", - "A6894-", - "G6895-", - "G6896-", - "G6897-", - "C6898-", - "A6899-", - "A6900-", - "A6901-", - "T6902-", - "G6903-", - "T6904-", - "C6905-", - "T6906-", - "G6907-", - "T6908-", - "A6909-", - "T6910-", - "A6911-", - "T6912-", - "A6913-", - "A6914-", - "T6915-", - "A6916-", - "T6917-", - "A6918-", - "C6919-", - "A6920-", - "T6921-", - "A6922-", - "A6923-", - "G6924-", - "T6925-", - "T6926-", - "A6927-", - "A6928-", - "T6929-", - "A6930-", - "G6931-", - "T6933-", - "T6934-", - "T6935-", - "T6936-", - "T6937-", - "A6938-", - "T6939-", - "C6940-", - "A6941-", - "T6942-", - "A6943-", - "T6944-", - "T6945-", - "T6946-", - "T6947-", - "C6948-", - "T6949-", - "A6950-", - "A6951-", - "T6952-", - "A6953-", - "C6954-", - "C6955-", - "A6956-", - "T6957-", - "A6958-", - "A6959-", - "T6960-", - "A6961-", - "A6962-", - "A6963-", - "A6964-", - "A6965-", - "T6966-", - "T6967-", - "A6968-", - "T6969-", - "C6970-", - "A6971-", - "T6972-", - "T6973-", - "A6974-", - "T6975-", - "G6976-", - "T6977-", - "G6978-", - "T6979-", - "T6980-", - "T6981-", - "G6982-", - "T6983-", - "G6984-", - "T6985-", - "A6986-", - "G6987-", - "A8366C", - "G8599A", - "G10923A", - "T12181A", - "T15122-", - "C17933T", - "T18703C", - "C21073A", - "G33053A", - "A35238G", - "A38984G", - "G46402T", - "G47539A", - "C47904-", - "C47905-", - "G64207A", - "T66182C", - "G69898A", - "A88356G", - "G102985T", - "C109017T", - "C115292T", - "G133070A", - "A136512C", - "A136534-", - "T136535-", - "C136536-", - "A136537-", - "T136538-", - "A136540-", - "T136541-", - "A136543-", - "T136544-", - "C136545-", - "C142360T", - "C145930-", - "G148718A", - "C152844T", - "C158803A", - "C159989T", - "C160938T", - "C166345A", - "G167529T", - "G169595A", - "A173273-", - "-173303T", - "-173304A", - "-173305T", - "C174599T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "C192693T", - "C195135T" - ], - "OPG002": [ - "A226V" - ], - "OPG003": [ - "H31Y" - ], - "OPG015": [ - "M1-", - "E2-", - "S3-", - "A4-", - "D5-", - "F6-", - "M7-", - "A8-", - "V9-", - "D10-", - "E11-", - "Q12-", - "F13-", - "H14-", - "D15-", - "D16-", - "L17-", - "D18-", - "L19-", - "W20-", - "S21-", - "L22-", - "S23-", - "L24-", - "V25-", - "D26-", - "D27-", - "Y28-", - "K29-", - "K30-", - "H31-", - "G32-", - "L33-", - "G34-", - "V35-", - "D36-", - "C37-", - "Y38-", - "V39-", - "L40-", - "E41-", - "P42-", - "V43-", - "V44-", - "D45-", - "R46-", - "K47-", - "I48-", - "F49-", - "D50-", - "R51-", - "F52-", - "L53-", - "L54-", - "E55-", - "P56-", - "I57-", - "C58-", - "D59-", - "P60-", - "V61-", - "D62-", - "V63-", - "L64-", - "Y65-", - "D66-", - "Y67-", - "F68-", - "R69-", - "I70-", - "H71-", - "R72-", - "D73-", - "N74-", - "I75-", - "D76-", - "Q77-", - "Y78-", - "I79-", - "V80-", - "D81-", - "R82-", - "L83-", - "F84-", - "A85-", - "Y86-", - "I87-", - "T88-", - "Y89-", - "K90-", - "D91-", - "I92-", - "I93-", - "S94-", - "A95-", - "L96-", - "V97-", - "S98-", - "K99-", - "N100-", - "Y101-", - "M102-", - "E103-", - "D104-", - "I105-", - "F106-", - "S107-", - "I108-", - "I109-", - "I110-", - "K111-", - "N112-", - "C113-", - "N114-", - "S115-", - "V116-", - "Q117-", - "D118-", - "L119-", - "L120-", - "L121-", - "Y122-", - "Y123-", - "L124-", - "S125-", - "N126-", - "A127-", - "Y128-", - "V129-", - "E130-", - "I131-", - "D132-", - "I133-", - "V134-", - "D135-", - "F136-", - "M137-", - "V138-", - "D139-", - "H140-", - "G141-", - "A142-", - "V143-", - "I144-", - "Y145-", - "K146-", - "I147-", - "E148-", - "C149-", - "L150-", - "N151-", - "A152-", - "Y153-", - "F154-", - "R155-", - "G156-", - "I157-", - "C158-", - "K159-", - "K160-", - "E161-", - "S162-", - "S163-", - "V164-", - "V165-", - "E166-", - "F167-", - "I168-", - "L169-", - "N170-", - "C171-", - "G172-", - "I173-", - "P174-", - "D175-", - "E176-", - "N177-", - "D178-", - "V179-", - "K180-", - "L181-", - "D182-", - "L183-", - "Y184-", - "K185-", - "I186-", - "I187-", - "Q188-", - "Y189-", - "T190-", - "R191-", - "G192-", - "F193-", - "L194-", - "V195-", - "D196-", - "E197-", - "P198-", - "T199-", - "V200-", - "L201-", - "E202-", - "I203-", - "Y204-", - "K205-", - "L206-", - "C207-", - "I208-", - "P209-", - "Y210-", - "I211-", - "E212-", - "D213-", - "I214-", - "N215-", - "Q216-", - "L217-", - "D218-", - "A219-", - "G220-", - "G221-", - "R222-", - "T223-", - "L224-", - "L225-", - "Y226-", - "R227-", - "A228-", - "I229-", - "Y230-", - "A231-", - "G232-", - "Y233-", - "I234-", - "D235-", - "L236-", - "V237-", - "S238-", - "W239-", - "L240-", - "L241-", - "E242-", - "N243-", - "G244-", - "A245-", - "N246-", - "V247-", - "N248-", - "A249-", - "V250-", - "M251-", - "S252-", - "N253-", - "G254-", - "Y255-", - "T256-", - "C257-", - "L258-", - "D259-", - "V260-", - "A261-", - "V262-", - "D263-", - "R264-", - "G265-", - "S266-", - "V267-", - "I268-", - "A269-", - "R270-", - "R271-", - "E272-", - "A273-", - "H274-", - "L275-", - "K276-", - "I277-", - "L278-", - "E279-", - "I280-", - "L281-", - "L282-", - "R283-", - "E284-", - "P285-", - "L286-", - "S287-", - "I288-", - "D289-", - "C290-", - "I291-", - "K292-", - "L293-", - "A294-", - "I295-", - "L296-", - "N297-", - "N298-", - "T299-", - "I300-", - "E301-", - "N302-", - "H303-", - "D304-", - "V305-", - "I306-", - "K307-", - "L308-", - "C309-", - "I310-", - "K311-", - "Y312-", - "F313-", - "M314-", - "M315-", - "V316-", - "D317-", - "Y318-", - "S319-", - "L320-", - "C321-", - "N322-", - "V323-", - "Y324-", - "A325-", - "S326-", - "S327-", - "L328-", - "F329-", - "D330-", - "Y331-", - "I332-", - "I333-", - "D334-", - "C335-", - "K336-", - "Q337-", - "E338-", - "L339-", - "E340-", - "Y341-", - "I342-", - "R343-", - "Q344-", - "M345-", - "K346-", - "I347-", - "H348-", - "N349-", - "T350-", - "T351-", - "M352-", - "Y353-", - "E354-", - "L355-", - "I356-", - "Y357-", - "N358-", - "R359-", - "D360-", - "K361-", - "N362-", - "K363-", - "H364-", - "A365-", - "S366-", - "H367-", - "I368-", - "L369-", - "H370-", - "R371-", - "Y372-", - "S373-", - "K374-", - "H375-", - "P376-", - "V377-", - "L378-", - "T379-", - "Q380-", - "C381-", - "I382-", - "T383-", - "K384-", - "G385-", - "F386-", - "K387-", - "I388-", - "Y389-", - "T390-", - "E391-", - "V392-", - "T393-", - "E394-", - "Q395-", - "V396-", - "T397-", - "K398-", - "A399-", - "L400-", - "N401-", - "R402-", - "R403-", - "A404-", - "L405-", - "I406-", - "D407-", - "E408-", - "I409-", - "I410-", - "N411-", - "N412-", - "V413-", - "S414-", - "T415-", - "D416-", - "D417-", - "N418-", - "L419-", - "L420-", - "S421-", - "K422-", - "L423-", - "P424-", - "L425-", - "E426-", - "I427-", - "R428-", - "D429-", - "L430-", - "I431-", - "V432-", - "S433-", - "Q434-", - "A435-", - "V436-", - "I437-", - "*438-" - ], - "OPG023": [ - "Q660*" - ], - "OPG025": [ - "N49X", - "*631X" - ], - "OPG031": [ - "C299Y" - ], - "OPG065": [ - "R28S" - ], - "OPG153": [ - "D375-", - "X376-", - "X377-", - "D378-", - "Y386D", - "X510*" - ], - "OPG187": [ - "A106V" - ], - "OPG191": [ - "S62X" - ], - "OPG193": [ - "D66Y" - ], - "OPG204": [ - "A23V" - ] - }, - "labels": { - "aa": "OPG002: A226V; OPG003: H31Y; OPG015: M1-, E2-, S3-, A4-, D5-, F6-, M7-, A8-, V9-, D10-, E11-, Q12-, F13-, H14-, D15-, D16-, L17-, D18-, L19-, W20-, S21-, L22-, S23-, L24-, V25-, D26-, D27-, Y28-, K29-, K30-, H31-, G32-, L33-, G34-, V35-, D36-, C37-, Y38-, V39-, L40-, E41-, P42-, V43-, V44-, D45-, R46-, K47-, I48-, F49-, D50-, R51-, F52-, L53-, L54-, E55-, P56-, I57-, C58-, D59-, P60-, V61-, D62-, V63-, L64-, Y65-, D66-, Y67-, F68-, R69-, I70-, H71-, R72-, D73-, N74-, I75-, D76-, Q77-, Y78-, I79-, V80-, D81-, R82-, L83-, F84-, A85-, Y86-, I87-, T88-, Y89-, K90-, D91-, I92-, I93-, S94-, A95-, L96-, V97-, S98-, K99-, N100-, Y101-, M102-, E103-, D104-, I105-, F106-, S107-, I108-, I109-, I110-, K111-, N112-, C113-, N114-, S115-, V116-, Q117-, D118-, L119-, L120-, L121-, Y122-, Y123-, L124-, S125-, N126-, A127-, Y128-, V129-, E130-, I131-, D132-, I133-, V134-, D135-, F136-, M137-, V138-, D139-, H140-, G141-, A142-, V143-, I144-, Y145-, K146-, I147-, E148-, C149-, L150-, N151-, A152-, Y153-, F154-, R155-, G156-, I157-, C158-, K159-, K160-, E161-, S162-, S163-, V164-, V165-, E166-, F167-, I168-, L169-, N170-, C171-, G172-, I173-, P174-, D175-, E176-, N177-, D178-, V179-, K180-, L181-, D182-, L183-, Y184-, K185-, I186-, I187-, Q188-, Y189-, T190-, R191-, G192-, F193-, L194-, V195-, D196-, E197-, P198-, T199-, V200-, L201-, E202-, I203-, Y204-, K205-, L206-, C207-, I208-, P209-, Y210-, I211-, E212-, D213-, I214-, N215-, Q216-, L217-, D218-, A219-, G220-, G221-, R222-, T223-, L224-, L225-, Y226-, R227-, A228-, I229-, Y230-, A231-, G232-, Y233-, I234-, D235-, L236-, V237-, S238-, W239-, L240-, L241-, E242-, N243-, G244-, A245-, N246-, V247-, N248-, A249-, V250-, M251-, S252-, N253-, G254-, Y255-, T256-, C257-, L258-, D259-, V260-, A261-, V262-, D263-, R264-, G265-, S266-, V267-, I268-, A269-, R270-, R271-, E272-, A273-, H274-, L275-, K276-, I277-, L278-, E279-, I280-, L281-, L282-, R283-, E284-, P285-, L286-, S287-, I288-, D289-, C290-, I291-, K292-, L293-, A294-, I295-, L296-, N297-, N298-, T299-, I300-, E301-, N302-, H303-, D304-, V305-, I306-, K307-, L308-, C309-, I310-, K311-, Y312-, F313-, M314-, M315-, V316-, D317-, Y318-, S319-, L320-, C321-, N322-, V323-, Y324-, A325-, S326-, S327-, L328-, F329-, D330-, Y331-, I332-, I333-, D334-, C335-, K336-, Q337-, E338-, L339-, E340-, Y341-, I342-, R343-, Q344-, M345-, K346-, I347-, H348-, N349-, T350-, T351-, M352-, Y353-, E354-, L355-, I356-, Y357-, N358-, R359-, D360-, K361-, N362-, K363-, H364-, A365-, S366-, H367-, I368-, L369-, H370-, R371-, Y372-, S373-, K374-, H375-, P376-, V377-, L378-, T379-, Q380-, C381-, I382-, T383-, K384-, G385-, F386-, K387-, I388-, Y389-, T390-, E391-, V392-, T393-, E394-, Q395-, V396-, T397-, K398-, A399-, L400-, N401-, R402-, R403-, A404-, L405-, I406-, D407-, E408-, I409-, I410-, N411-, N412-, V413-, S414-, T415-, D416-, D417-, N418-, L419-, L420-, S421-, K422-, L423-, P424-, L425-, E426-, I427-, R428-, D429-, L430-, I431-, V432-, S433-, Q434-, A435-, V436-, I437-, *438-; OPG023: Q660*; OPG025: N49X, *631X; OPG031: C299Y; OPG065: R28S; OPG153: D375-, X376-, X377-, D378-, Y386D, X510*; OPG187: A106V; OPG191: S62X; OPG193: D66Y; OPG204: A23V" - } - } - }, - { - "name": "NODE_0000005", - "node_attrs": { - "div": 291, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G8394T", - "C10147T", - "G11051A", - "G15606A", - "G18280A", - "G21146T", - "T32747C", - "G36045T", - "C39311G", - "A45542G", - "G84665A", - "A92711G", - "G114697T", - "G135808A", - "-136539G", - "-140105A", - "-140106T", - "-140107A", - "-140108A", - "-140109C", - "-140110A", - "-140111A", - "-140112T", - "-140113T", - "C148484T", - "T148958C", - "C156205T", - "-156206C", - "G169718-", - "A169719-", - "T169720-", - "A169721-", - "C169722-", - "A169723-", - "C170542T", - "A172881-", - "-173274A", - "-173275T", - "-173276A", - "-173277T", - "-173278A", - "-173279T", - "-173280A", - "-173281T", - "-173282A", - "-173283T", - "-173284A", - "-173285T", - "-173286A", - "-173287T", - "-173288A", - "-173289T", - "-173290A", - "-173291T", - "-173292A", - "-173293T", - "-173294A", - "A173306-", - "T173307-", - "A173308-", - "T173309-", - "A173310-", - "T173311-", - "A173312-", - "T173313-", - "A173314-", - "T173315-", - "A173316-", - "T173317-", - "G173318-", - "G173595A", - "G176943A", - "C188468T", - "A188511G", - "C190447T", - "A190929-", - "A190980-", - "G190981-", - "A190982-", - "A190983-", - "T190984-", - "A192419-", - "A192420-", - "G192421-", - "T192422-", - "C192423-", - "A192424-", - "T192425-", - "A192426-", - "A192427-", - "G192428-", - "T192429-", - "T192430-", - "A192431-", - "G192432-", - "T192433-", - "T192434-" - ], - "NBT03_gp174": [ - "A13V", - "K174X", - "*177X" - ], - "OPG023": [ - "A617V" - ], - "OPG037": [ - "H430N" - ], - "OPG055": [ - "L347I" - ], - "OPG133": [ - "P334T" - ], - "OPG153": [ - "X377H" - ], - "OPG159": [ - "X113N", - "-114N", - "-115N", - "X116Y", - "X146*" - ], - "OPG197": [ - "D17-", - "T18-" - ], - "OPG198": [ - "H169Y" - ], - "OPG205": [ - "A430T" - ] - }, - "labels": { - "aa": "NBT03_gp174: A13V, K174X, *177X; OPG023: A617V; OPG037: H430N; OPG055: L347I; OPG133: P334T; OPG153: X377H; OPG159: X113N, -114N, -115N, X116Y, X146*; OPG197: D17-, T18-; OPG198: H169Y; OPG205: A430T" - } - }, - "children": [ - { - "name": "KJ642619", - "node_attrs": { - "div": 293, - "author": { - "author": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Lil,Y., Weil,R.M., Muyembe,J.-J., Kingbeni,P.M., Balilo,M.", - "value": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Lil,Y., Weil,R.M., Muyembe,J.-J., Kingbeni,P.M., Balilo,M." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA" - }, - "date": { - "value": "1988-XX-XX" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "KJ642619" - }, - "strain": { - "value": "KJ642619" - }, - "country": { - "value": "Gabon" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A24147T", - "T24148A" - ] - } - } - }, - { - "name": "BNITM-Gabon1988", - "node_attrs": { - "div": 295, - "author": { - "author": "Emmerich,P., Bialonski,A., Tomazatos,A., Cadar,D.", - "value": "Emmerich,P., Bialonski,A., Tomazatos,A., Cadar,D." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Bernhard Nocht Institute for Tropical Medicine, Arbovirology and Entomology" - }, - "date": { - "value": "1988-XX-XX" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "BNITM-Gabon1988" - }, - "strain": { - "value": "OP498046" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Gabon" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G11865C", - "T24612C", - "C151380T", - "G171690A" - ], - "OPG023": [ - "L346V" - ], - "OPG199": [ - "D235N" - ] - }, - "labels": { - "aa": "OPG023: L346V; OPG199: D235N" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000006", - "node_attrs": { - "div": 274, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G40182A", - "C54569A", - "G56397T", - "C57678T", - "C87267T", - "C109535A", - "G122405A", - "A134326G", - "G145959A", - "G146433A", - "A165096G", - "-179226T", - "A179227-", - "A179236G", - "G187305A" - ], - "OPG057": [ - "A5V" - ], - "OPG072": [ - "L34I" - ], - "OPG143": [ - "A304V" - ], - "OPG170": [ - "H116Y" - ] - }, - "labels": { - "aa": "OPG057: A5V; OPG072: L34I; OPG143: A304V; OPG170: H116Y" - } - }, - "children": [ - { - "name": "KJ642612", - "node_attrs": { - "div": 294, - "author": { - "author": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Lil,Y., Weil,R.M., Muyembe,J.-J., Kingbeni,P.M., Balilo,M.", - "value": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Lil,Y., Weil,R.M., Muyembe,J.-J., Kingbeni,P.M., Balilo,M." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA" - }, - "date": { - "value": "1986-XX-XX" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "KJ642612" - }, - "strain": { - "value": "KJ642612" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G18301A", - "G31718A", - "T33822A", - "G35972T", - "G39173A", - "G53569A", - "G53953A", - "T77412A", - "T90138C", - "A91005G", - "G96915A", - "G107670A", - "C117896T", - "C128183A", - "G150582T", - "T151256A", - "T151769C", - "C176495T", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216T", - "A179218G", - "T179228-", - "T179229-", - "A179230-", - "T179231-", - "A179232-", - "T179233-", - "A179234-", - "A181246-", - "C181619T", - "T187676C", - "A187974-", - "T187975-", - "A190302G", - "G197006T" - ], - "OPG054": [ - "P9T" - ] - }, - "labels": { - "aa": "OPG054: P9T" - } - } - }, - { - "name": "NODE_0000007", - "node_attrs": { - "div": 287, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T617-", - "C5340T", - "C8344A", - "C15209A", - "C21369A", - "T52086C", - "A71174-", - "C76021T", - "T82313C", - "G98856A", - "G122351A", - "G129583T", - "T148336-", - "T150936C", - "G154730A", - "C169752T", - "A169769-", - "C169770-", - "A169771-", - "G169772-", - "A169773-", - "T169774-", - "G169775-", - "T169776-", - "A169777-", - "G169778-", - "A169779-", - "A169780-", - "G169781-", - "A169782-", - "T169783-", - "A169784-", - "T169785-", - "C169786-", - "A169787-", - "T169788-", - "G169789-", - "A169790-", - "A169791-", - "C169792-", - "G169793-", - "A169794-", - "A169795G", - "A169796T", - "C171561T", - "-179227G", - "G191870A", - "A196588-" - ], - "NBT03_gp175": [ - "A273T" - ], - "OPG015": [ - "A273T" - ], - "OPG025": [ - "S20I" - ], - "OPG037": [ - "M355I" - ], - "OPG071": [ - "N785D" - ], - "OPG143": [ - "A322V" - ], - "OPG181": [ - "A107T" - ], - "OPG197": [ - "T28I", - "T34-", - "D35-", - "V36-", - "E37-", - "D38-", - "I39-", - "M40-", - "N41-", - "E42X", - "I43L", - "*101X" - ], - "OPG199": [ - "P192S" - ] - }, - "labels": { - "aa": "NBT03_gp175: A273T; OPG015: A273T; OPG025: S20I; OPG037: M355I; OPG071: N785D; OPG143: A322V; OPG181: A107T; OPG197: T28I, T34-, D35-, V36-, E37-, D38-, I39-, M40-, N41-, E42X, I43L, *101X; OPG199: P192S" - } - }, - "children": [ - { - "name": "NODE_0000008", - "node_attrs": { - "div": 288, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G32003A" - ] - } - }, - "children": [ - { - "name": "DRC 06-0970", - "node_attrs": { - "div": 288, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2006-10-31" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 06-0970" - }, - "strain": { - "value": "JX878408" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "DRC 07-0450", - "node_attrs": { - "div": 297, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2007-05-27" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 07-0450" - }, - "strain": { - "value": "JX878426" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G19563A", - "G38096T", - "G54227A", - "-71174A", - "A72767T", - "G111583A", - "T121790C", - "A160332-", - "C166976T", - "C185501T", - "G189591A" - ], - "OPG005": [ - "M131I" - ], - "OPG034": [ - "A148V" - ], - "OPG071": [ - "T71I" - ], - "OPG092": [ - "S61T" - ], - "OPG130": [ - "T107I" - ], - "OPG141": [ - "I45M" - ] - }, - "labels": { - "aa": "OPG005: M131I; OPG034: A148V; OPG071: T71I; OPG092: S61T; OPG130: T107I; OPG141: I45M" - } - } - } - ] - }, - { - "name": "NODE_0000009", - "node_attrs": { - "div": 288, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C19745T" - ] - } - }, - "children": [ - { - "name": "DRC 07-0120", - "node_attrs": { - "div": 299, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2007-01-02" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 07-0120" - }, - "strain": { - "value": "JX878418" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G1934A", - "A50236G", - "G60803T", - "G74360A", - "G95577A", - "G116628T", - "C120371T", - "C151006A", - "C174070T", - "G187369A", - "A187951C", - "C195276T" - ], - "OPG002": [ - "T273M" - ], - "OPG069": [ - "Q84R" - ], - "OPG080": [ - "L406I" - ], - "OPG094": [ - "R194H" - ], - "OPG116": [ - "D73N" - ], - "OPG134": [ - "*293Y" - ], - "OPG135": [ - "S95Y" - ], - "OPG137": [ - "A257V" - ] - }, - "labels": { - "aa": "OPG002: T273M; OPG069: Q84R; OPG080: L406I; OPG094: R194H; OPG116: D73N; OPG134: *293Y; OPG135: S95Y; OPG137: A257V" - } - } - }, - { - "name": "NC_003310", - "node_attrs": { - "div": 382, - "author": { - "author": "Senkevich,T.G., Yutin,N., Wolf,Y.I., Koonin,E.V., Moss,B., Zmasek,C.M., Knipe,D.M., Pellett,P.E., Scheuermann,R.H., Shchelkunov,S.N., Totmenin,A.V., Babkin,I.V., Safronov,P.F., Ryazankina,O.I., Petrov,N.A., Gutorov,V.V., Uvarova,E.A., Mikheev,M.V., Sisler,J.R., Esposito,J.J., Jahrling,P.B., Sandakhchiev,L.S.", - "value": "Senkevich,T.G., Yutin,N., Wolf,Y.I., Koonin,E.V., Moss,B., Zmasek,C.M., Knipe,D.M., Pellett,P.E., Scheuermann,R.H., Shchelkunov,S.N., Totmenin,A.V., Babkin,I.V., Safronov,P.F., Ryazankina,O.I., Petrov,N.A., Gutorov,V.V., Uvarova,E.A., Mikheev,M.V., Sisler,J.R., Esposito,J.J., Jahrling,P.B., Sandakhchiev,L.S." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Department of Molecular Biology of Genomes, SRC VB Vector, Russia" - }, - "date": { - "value": "1996-XX-XX" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "NC_003310" - }, - "strain": { - "value": "NC_003310" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T2688A", - "G9441A", - "A24393T", - "C24945T", - "C26416T", - "A27108-", - "T27328C", - "C29029T", - "T29031C", - "T29753C", - "T29763C", - "T30743A", - "T30815A", - "T30855A", - "G32024A", - "A32322G", - "T32329C", - "T33159C", - "G34800A", - "T34944A", - "G35230A", - "G35775A", - "T37957A", - "C38427T", - "T38658A", - "-39070T", - "T39447C", - "A40487T", - "A50294G", - "G59966C", - "T60903A", - "C60947T", - "T61241C", - "A61926C", - "T62169A", - "G62941T", - "T65141C", - "T65870C", - "A67348G", - "C67353T", - "A70503T", - "T71422C", - "A73777T", - "T74112C", - "A75351T", - "C76284T", - "T78525C", - "A81968-", - "C82417T", - "T82548C", - "T82641G", - "C83956T", - "G88318A", - "T108302C", - "A115794G", - "T122451C", - "T122935C", - "T122986C", - "T124980C", - "T125566C", - "T125834C", - "T126192C", - "T126231C", - "T126963C", - "T130725C", - "A130822C", - "G134912A", - "T136637C", - "T138948C", - "T139755C", - "T140893C", - "T141277A", - "A141901G", - "G142068A", - "A143024T", - "G143126A", - "A143187T", - "A143703G", - "C143806T", - "T143895C", - "C158963T", - "G161650A", - "T165054-", - "C165055-", - "G166518A", - "C167064T", - "T168214-", - "A168956-", - "A169024-", - "T169162-", - "A169581-", - "T169894C", - "A170077G", - "C182952T", - "T182953C", - "C183492A", - "C183522A", - "C184979T", - "A185373G", - "G185472A", - "T186503C", - "T186531G", - "C186532T", - "A187305G", - "A194522T" - ], - "OPG002": [ - "I22L" - ], - "OPG042": [ - "G228R" - ], - "OPG043": [ - "N210D" - ], - "OPG045": [ - "R78G" - ], - "OPG047": [ - "N114Y", - "E127V", - "H151L", - "N478D", - "E481G" - ], - "OPG049": [ - "T275A", - "M277T" - ], - "OPG054": [ - "A256V" - ], - "OPG056": [ - "N126I", - "C203Y", - "T360S" - ], - "OPG057": [ - "N250S" - ], - "OPG059": [ - "Y49*" - ], - "OPG080": [ - "S260G", - "G358R", - "P685A" - ], - "OPG082": [ - "T171K" - ], - "OPG085": [ - "L395P" - ], - "OPG089": [ - "K213I" - ], - "OPG091": [ - "F18S" - ], - "OPG097": [ - "D198N" - ], - "OPG101": [ - "F14L" - ], - "OPG105": [ - "R281X", - "A431V", - "C475R", - "Y506D", - "S944F", - "*1287X" - ], - "OPG109": [ - "A377V" - ], - "OPG127": [ - "K175R" - ], - "OPG143": [ - "T289A" - ], - "OPG145": [ - "L345P" - ], - "OPG146": [ - "D25G" - ], - "OPG147": [ - "S52G" - ], - "OPG151": [ - "M601T", - "E633D" - ], - "OPG153": [ - "N344S" - ], - "OPG156": [ - "I154M" - ], - "OPG160": [ - "K61R" - ], - "OPG161": [ - "L59Q" - ], - "OPG162": [ - "R84G" - ], - "OPG164": [ - "N83Y", - "E117K", - "Q137L" - ], - "OPG165": [ - "D63G", - "I127T" - ], - "OPG185": [ - "A16V" - ], - "OPG188": [ - "G19R" - ], - "OPG191": [ - "A120T" - ], - "OPG192": [ - "H112Y" - ], - "OPG198": [ - "K14E" - ], - "OPG210": [ - "L533S", - "P713T", - "P723T", - "T1340A", - "A1373T", - "S1726V" - ] - }, - "labels": { - "aa": "OPG002: I22L; OPG042: G228R; OPG043: N210D; OPG045: R78G; OPG047: N114Y, E127V, H151L, N478D, E481G; OPG049: T275A, M277T; OPG054: A256V; OPG056: N126I, C203Y, T360S; OPG057: N250S; OPG059: Y49*; OPG080: S260G, G358R, P685A; OPG082: T171K; OPG085: L395P; OPG089: K213I; OPG091: F18S; OPG097: D198N; OPG101: F14L; OPG105: R281X, A431V, C475R, Y506D, S944F, *1287X; OPG109: A377V; OPG127: K175R; OPG143: T289A; OPG145: L345P; OPG146: D25G; OPG147: S52G; OPG151: M601T, E633D; OPG153: N344S; OPG156: I154M; OPG160: K61R; OPG161: L59Q; OPG162: R84G; OPG164: N83Y, E117K, Q137L; OPG165: D63G, I127T; OPG185: A16V; OPG188: G19R; OPG191: A120T; OPG192: H112Y; OPG198: K14E; OPG210: L533S, P713T, P723T, T1340A, A1373T, S1726V" - } - } - } - ] - }, - { - "name": "NODE_0000010", - "node_attrs": { - "div": 293, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A7494-", - "C7495-", - "A7496-", - "A7497-", - "T7498-", - "T7499-", - "G24032A", - "G94972A", - "G137606T", - "C149206G", - "G160867A", - "C170296A" - ], - "OPG115": [ - "V105I" - ], - "OPG153": [ - "A21E" - ], - "OPG174": [ - "E64Q" - ], - "OPG198": [ - "L87M" - ] - }, - "labels": { - "aa": "OPG115: V105I; OPG153: A21E; OPG174: E64Q; OPG198: L87M" - } - }, - "children": [ - { - "name": "DRC 07-0275", - "node_attrs": { - "div": 293, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2007-02-10" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 07-0275" - }, - "strain": { - "value": "JX878419" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "DRC 07-0283", - "node_attrs": { - "div": 293, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2007-02-26" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 07-0283" - }, - "strain": { - "value": "JX878420" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A8049-" - ] - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000011", - "node_attrs": { - "div": 263, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T458-", - "A459-", - "G460-", - "C7756A", - "-140105A", - "-140106T", - "-140107A", - "-140108A", - "-140109C", - "-140110A", - "-140111A", - "-140112T", - "-140113T", - "-146860T", - "-146861A", - "-146869T", - "-146870A", - "-146871T", - "-146872T", - "-146873T", - "-146874T", - "-146875A", - "-146876T", - "-146878T", - "-146879T", - "G150568-", - "-179226C", - "C196750-", - "T196751-", - "A196752-" - ], - "OPG159": [ - "X113N", - "-114N", - "-115N", - "X116Y", - "X146*" - ] - }, - "labels": { - "aa": "OPG159: X113N, -114N, -115N, X116Y, X146*" - } - }, - "children": [ - { - "name": "NODE_0000012", - "node_attrs": { - "div": 270, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C115912T", - "G148121A", - "A148344T", - "C155631A", - "G169205T", - "C176693T", - "G186892T", - "G196420A" - ], - "OPG173": [ - "V29I" - ], - "OPG210": [ - "R1846I" - ] - }, - "labels": { - "aa": "OPG173: V29I; OPG210: R1846I" - } - }, - "children": [ - { - "name": "MT724771", - "node_attrs": { - "div": 305, - "author": { - "author": "Marien,J., Laudisoit,A., Patrono,Lv., Calvignac-Spencer,S., Leendertz,F., Leirs,H., Verheyen,E.", - "value": "Marien,J., Laudisoit,A., Patrono,Lv., Calvignac-Spencer,S., Leendertz,F., Leirs,H., Verheyen,E." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Biology, Universiteit Antwerpen, Belgium" - }, - "date": { - "value": "2014-01-01" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "MT724771" - }, - "strain": { - "value": "MT724771" - }, - "host": { - "value": "Funisciurus bayonii" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T517-", - "A518-", - "C2455T", - "T7035-", - "T7036-", - "C7037-", - "T7038-", - "-7404T", - "T7409A", - "A7949G", - "T8287-", - "C8288-", - "T8289-", - "G8290-", - "T8291-", - "G8292-", - "C8941-", - "A9331G", - "C9784T", - "T10919C", - "C13547T", - "A21443G", - "A24211-", - "T24212-", - "C25370-", - "A25371-", - "T25372-", - "C25373-", - "C25374-", - "C25375-", - "T32188-", - "T32189-", - "T32190-", - "G34746A", - "A37269G", - "A40501G", - "A41912-", - "G46543A", - "G50487-", - "T50488-", - "A50489-", - "T50490-", - "G57009A", - "C63390T", - "C69229T", - "G76690T", - "T77421A", - "G78942A", - "G83798A", - "G88547A", - "T93188G", - "G107670A", - "T131098A", - "T134190C", - "G138882A", - "G139362-", - "G139363-", - "G139364-", - "T140624A", - "C142523-", - "C150966-", - "A150967-", - "T150968-", - "C150969-", - "A150970-", - "G150971-", - "C152226-", - "C152227-", - "G152228-", - "A152800T", - "C153210A", - "C155366-", - "C155574A", - "A163115-", - "A163116-", - "G163117-", - "G163118-", - "T163119-", - "A163120-", - "A163121-", - "A163122-", - "A169672T", - "A170118T", - "G173205A", - "-173302A", - "-173303T", - "-173304A", - "-173305T", - "A174499-", - "T174500-", - "A174501-", - "A174502-", - "T174503-", - "T174504-", - "A174505-", - "T174506-", - "C174507-", - "T174508-", - "T174509-", - "A174510-", - "C183430A", - "A183443-", - "C183444-", - "T183445-", - "G185783A", - "-190198A", - "-190199C", - "C190386-", - "T190405A", - "A190697T" - ], - "NBT03_gp174": [ - "E96D" - ], - "OPG019": [ - "R124G" - ], - "OPG025": [ - "W574*" - ], - "OPG037": [ - "Y331H" - ], - "OPG040": [ - "G35X", - "D36-", - "E37X", - "*376X" - ], - "OPG056": [ - "I589T" - ], - "OPG087": [ - "L125F" - ], - "OPG101": [ - "A153T" - ], - "OPG109": [ - "R301C" - ], - "OPG113": [ - "N486K" - ], - "OPG151": [ - "S725R" - ], - "OPG156": [ - "P16-" - ], - "OPG160": [ - "T151S" - ], - "OPG163": [ - "Q108X", - "*177X" - ], - "OPG180": [ - "T37S" - ], - "OPG181": [ - "P319X", - "*335X" - ], - "OPG210": [ - "P692H", - "P696X", - "L697X" - ] - }, - "labels": { - "aa": "NBT03_gp174: E96D; OPG019: R124G; OPG025: W574*; OPG037: Y331H; OPG040: G35X, D36-, E37X, *376X; OPG056: I589T; OPG087: L125F; OPG101: A153T; OPG109: R301C; OPG113: N486K; OPG151: S725R; OPG156: P16-; OPG160: T151S; OPG163: Q108X, *177X; OPG180: T37S; OPG181: P319X, *335X; OPG210: P692H, P696X, L697X" - } - } - }, - { - "name": "NODE_0000013", - "node_attrs": { - "div": 272, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C790T", - "G152154A", - "C177720T" - ], - "OPG205": [ - "R689C" - ] - }, - "labels": { - "aa": "OPG205: R689C" - } - }, - "children": [ - { - "name": "Yambuku_DRC_1985", - "node_attrs": { - "div": 283, - "author": { - "author": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Yoshinori,N., Muyembe,J.-J., Kingbeni,P.M.", - "value": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Yoshinori,N., Muyembe,J.-J., Kingbeni,P.M." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA" - }, - "date": { - "value": "1985-XX-XX" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "Yambuku_DRC_1985" - }, - "strain": { - "value": "KP849471" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C204A", - "G3975A", - "G12958A", - "A17046T", - "G60368A", - "C83195T", - "G85079A", - "G86364A", - "G133454A", - "-146877A", - "-146880T", - "T148335-", - "T148336-", - "G150484A", - "-150568G", - "G150582T", - "G156302A", - "G180598A", - "C193235T", - "G197006T" - ], - "OPG029": [ - "D8E" - ], - "OPG080": [ - "P551S" - ], - "OPG176": [ - "D226N" - ] - }, - "labels": { - "aa": "OPG029: D8E; OPG080: P551S; OPG176: D226N" - } - } - }, - { - "name": "NODE_0000014", - "node_attrs": { - "div": 278, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T8510C", - "C16123A", - "C51889T", - "T87138C", - "G136499A", - "T136541A", - "-146877T", - "-146880A", - "G151145A", - "T178510-" - ], - "OPG027": [ - "E85D" - ], - "OPG153": [ - "D376V", - "P390L" - ] - }, - "labels": { - "aa": "OPG027: E85D; OPG153: D376V, P390L" - } - }, - "children": [ - { - "name": "DRC 06-1070", - "node_attrs": { - "div": 279, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2006-11-24" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 06-1070" - }, - "strain": { - "value": "JX878410" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T8470C", - "-8471T" - ] - } - } - }, - { - "name": "NODE_0000015", - "node_attrs": { - "div": 290, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T7058G", - "G24032A", - "C69800T", - "T71738C", - "C79473A", - "G104054T", - "G141897A", - "T148336-", - "G153208A", - "C162040T", - "C163571T", - "G165428A", - "A170972-", - "-178510T", - "A181246-", - "T183992C", - "A186633G", - "A189692-" - ], - "OPG088": [ - "A22T" - ], - "OPG102": [ - "P130H" - ], - "OPG180": [ - "A173T" - ], - "OPG188": [ - "L149F" - ], - "OPG189": [ - "A80V" - ], - "OPG190": [ - "G103S" - ], - "OPG210": [ - "T1760A" - ] - }, - "labels": { - "aa": "OPG088: A22T; OPG102: P130H; OPG180: A173T; OPG188: L149F; OPG189: A80V; OPG190: G103S; OPG210: T1760A" - } - }, - "children": [ - { - "name": "DRC 06-1076", - "node_attrs": { - "div": 293, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2006-11-30" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 06-1076" - }, - "strain": { - "value": "JX878412" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A134C", - "C204A", - "G15850T", - "C99681T", - "C129086T" - ], - "OPG151": [ - "P55S" - ] - }, - "labels": { - "aa": "OPG151: P55S" - } - } - }, - { - "name": "NODE_0000016", - "node_attrs": { - "div": 291, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T6932-", - "G115548A" - ], - "OPG133": [ - "P50L" - ] - }, - "labels": { - "aa": "OPG133: P50L" - } - }, - "children": [ - { - "name": "DRC 06-0999", - "node_attrs": { - "div": 291, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2006-11-09" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 06-0999" - }, - "strain": { - "value": "JX878409" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "DRC 06-1075", - "node_attrs": { - "div": 291, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2006-11-30" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 06-1075" - }, - "strain": { - "value": "JX878411" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000017", - "node_attrs": { - "div": 289, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C204A", - "G1750A", - "G11111A", - "G14622A", - "C25557T", - "C47009T", - "T49703C", - "C85076T", - "A136541T", - "G140367T", - "C173464T", - "C188051T", - "G190541A", - "C195460T" - ], - "OPG023": [ - "A597V" - ], - "OPG025": [ - "R216C" - ], - "OPG153": [ - "V376D" - ] - }, - "labels": { - "aa": "OPG023: A597V; OPG025: R216C; OPG153: V376D" - } - }, - "children": [ - { - "name": "DRC 07-0287", - "node_attrs": { - "div": 291, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2007-03-20" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 07-0287" - }, - "strain": { - "value": "JX878422" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A66164C", - "C144356T", - "G197006T", - "T197076G" - ], - "OPG084": [ - "Q481H" - ] - }, - "labels": { - "aa": "OPG084: Q481H" - } - } - }, - { - "name": "NODE_0000018", - "node_attrs": { - "div": 290, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C187388G" - ] - } - }, - "children": [ - { - "name": "DRC 07-0514", - "node_attrs": { - "div": 290, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2007-06-30" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 07-0514" - }, - "strain": { - "value": "JX878428" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000019", - "node_attrs": { - "div": 292, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T8470C", - "-8471T", - "A14622G", - "T136541A" - ], - "OPG025": [ - "C216R" - ], - "OPG153": [ - "D376V" - ] - }, - "labels": { - "aa": "OPG025: C216R; OPG153: D376V" - } - }, - "children": [ - { - "name": "DRC 07-0046", - "node_attrs": { - "div": 292, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2006-12-14" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 07-0046" - }, - "strain": { - "value": "JX878414" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "DRC 07-0093", - "node_attrs": { - "div": 293, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2006-12-26" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 07-0093" - }, - "strain": { - "value": "JX878416" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G50130A" - ], - "OPG069": [ - "D49N" - ] - }, - "labels": { - "aa": "OPG069: D49N" - } - } - }, - { - "name": "DRC 07-0286", - "node_attrs": { - "div": 293, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2007-03-22" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 07-0286" - }, - "strain": { - "value": "JX878421" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A204C", - "G174812T" - ], - "OPG204": [ - "R94M" - ] - }, - "labels": { - "aa": "OPG204: R94M" - } - } - }, - { - "name": "DRC 07-0480", - "node_attrs": { - "div": 292, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2007-05-25" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 07-0480" - }, - "strain": { - "value": "JX878427" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C144356-", - "G197006T", - "T197076G" - ] - } - } - }, - { - "name": "DRC 07-0045", - "node_attrs": { - "div": 292, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2006-12-14" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 07-0045" - }, - "strain": { - "value": "JX878413" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "DRC 07-0092", - "node_attrs": { - "div": 292, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2006-12-26" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 07-0092" - }, - "strain": { - "value": "JX878415" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000021", - "node_attrs": { - "div": 267, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G1319T", - "-46643T", - "G70874A", - "C130660T", - "G135598A", - "G144339-", - "T159792C", - "C195891A" - ], - "OPG001": [ - "T86N" - ], - "OPG089": [ - "E337K" - ] - }, - "labels": { - "aa": "OPG001: T86N; OPG089: E337K" - } - }, - "children": [ - { - "name": "NODE_0000022", - "node_attrs": { - "div": 273, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C8994A", - "A56010G", - "C81524T", - "C94783T", - "C141329T", - "G148121A", - "G150582-", - "A150583-", - "T150584-", - "G150585-", - "A150586-" - ], - "OPG115": [ - "H42Y" - ], - "OPG173": [ - "V29I" - ] - }, - "labels": { - "aa": "OPG115: H42Y; OPG173: V29I" - } - }, - "children": [ - { - "name": "NODE_0000023", - "node_attrs": { - "div": 276, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6645T", - "G108249A", - "C133977-", - "A133978-", - "A133979-", - "-146877A", - "-146880T", - "T148343A", - "-173304A", - "-173305T", - "A184202C" - ], - "OPG127": [ - "H193Y" - ] - }, - "labels": { - "aa": "OPG127: H193Y" - } - }, - "children": [ - { - "name": "KC257460", - "node_attrs": { - "div": 283, - "author": { - "author": "Nakazawa,Y., Emerson,G.L., Carroll,D.S., Zhao,H., Li,Y., Reynolds,M.G., Karem,K.L., Olson,V.A., Lash,R.R., Davidson,W.B., Smith,S.K., Levine,R.S., Regnery,R.L., Sammons,S.A., Frace,M.A., Mutasim,E.M., Karsani,M.E., Muntasir,M.O., Babiker,A.A., Opoka,L., Chowdhary,V., Damon,I.K., Karsani,M.E.M.", - "value": "Nakazawa,Y., Emerson,G.L., Carroll,D.S., Zhao,H., Li,Y., Reynolds,M.G., Karem,K.L., Olson,V.A., Lash,R.R., Davidson,W.B., Smith,S.K., Levine,R.S., Regnery,R.L., Sammons,S.A., Frace,M.A., Mutasim,E.M., Karsani,M.E., Muntasir,M.O., Babiker,A.A., Opoka,L., Chowdhary,V., Damon,I.K., Karsani,M.E.M." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Biochemistry & Microbiology, University of Victoria, Canada" - }, - "date": { - "value": "1985-XX-XX" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "KC257460" - }, - "strain": { - "value": "KC257460" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C457-", - "A461-", - "T462-", - "T463-", - "G464-", - "G465-", - "A579-", - "G580-", - "A583G", - "T12938-", - "A12939-", - "A21066G", - "G45419T", - "G46543A", - "C55215T", - "C136551G", - "C136554-", - "C136555-", - "G164590A", - "C169530A", - "G169775A", - "T169776A", - "-170914G", - "G182700T", - "A183506-", - "C183507-", - "C183508-", - "A183509-", - "G183510-", - "T183511-", - "C183512-", - "C183513-", - "A183514-", - "A183515-", - "A183516-", - "A183517-", - "T183518-", - "C183519-", - "C183520-", - "G183521-", - "C183522-", - "C183523-", - "A183524-", - "C183525-", - "A183526-", - "A183527-", - "C183528-", - "T183529-", - "T183530-", - "C183531-", - "C183532-", - "C183533-", - "C183534-", - "C183535-", - "T183536-", - "A183537-", - "G183538-", - "T196627-", - "C196628-", - "T196629C", - "G196744-", - "C196745-", - "C196746-", - "A196747-", - "A196748-", - "T196749-" - ], - "OPG153": [ - "M371X", - "D372X", - "D373H", - "*510X" - ], - "OPG189": [ - "A420T" - ], - "OPG197": [ - "V36K" - ], - "OPG210": [ - "G449C", - "K717X", - "P718-", - "V719-", - "Q720-", - "N721-", - "P722-", - "P723-", - "Q724-", - "L725-", - "P726-", - "P727-", - "R728X" - ] - }, - "labels": { - "aa": "OPG153: M371X, D372X, D373H, *510X; OPG189: A420T; OPG197: V36K; OPG210: G449C, K717X, P718-, V719-, Q720-, N721-, P722-, P723-, Q724-, L725-, P726-, P727-, R728X" - } - } - }, - { - "name": "NODE_0000024", - "node_attrs": { - "div": 287, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C204A", - "G6146A", - "T11318C", - "C19628T", - "C33967G", - "T35962C", - "A42121C", - "T46643-", - "C126969T", - "C138190A", - "G166163A", - "G171413A", - "-173290A", - "-173291T", - "-173292A", - "-173293T", - "-173294A", - "-173295T", - "-173296A", - "-173297T", - "-173298A", - "-173299T", - "-173300A", - "-173301T", - "-173302A", - "-173303T", - "C178333T", - "C179226T", - "A179227G", - "A179236G", - "C191064T", - "G197006T" - ], - "NBT03_gp175": [ - "A4V" - ], - "OPG015": [ - "A4V" - ], - "OPG023": [ - "Y528C" - ], - "OPG052": [ - "S10T" - ], - "OPG054": [ - "Q12R" - ], - "OPG155": [ - "R101I" - ], - "OPG191": [ - "M1I" - ], - "OPG199": [ - "M142I" - ] - }, - "labels": { - "aa": "NBT03_gp175: A4V; OPG015: A4V; OPG023: Y528C; OPG052: S10T; OPG054: Q12R; OPG155: R101I; OPG191: M1I; OPG199: M142I" - } - }, - "children": [ - { - "name": "Zaire_1979-005", - "node_attrs": { - "div": 287, - "author": { - "author": "Likos,A.M., Sammons,S.A., Olson,V.A., Frace,A.M., Li,Y., Olsen-Rasmussen,M., Davidson,W., Galloway,R., Khristova,M.L., Reynolds,M.G., Zhao,H., Carroll,D.S., Curns,A., Formenty,P., Esposito,J.J., Regnery,R.L., Damon,I.K., Olsen-Rasmussen,M.S.", - "value": "Likos,A.M., Sammons,S.A., Olson,V.A., Frace,A.M., Li,Y., Olsen-Rasmussen,M., Davidson,W., Galloway,R., Khristova,M.L., Reynolds,M.G., Zhao,H., Carroll,D.S., Curns,A., Formenty,P., Esposito,J.J., Regnery,R.L., Damon,I.K., Olsen-Rasmussen,M.S." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Centers for Disease Control and Prevention, National Center for Infectious Diseases" - }, - "date": { - "value": "1978-XX-XX" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "Zaire_1979-005" - }, - "strain": { - "value": "DQ011155" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Zaire 1979-005", - "node_attrs": { - "div": 329, - "author": { - "author": "Farlow,J., Ichou,M.A., Huggins,J., Ibrahim,S., Ait Ichou,M., Ibrahims,S.", - "value": "Farlow,J., Ichou,M.A., Huggins,J., Ibrahim,S., Ait Ichou,M., Ibrahims,S." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Virology, The United States Army Medical Research Institute for Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "1979-XX-XX" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "Zaire 1979-005" - }, - "strain": { - "value": "HM172544" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6897A", - "C13503T", - "C24977-", - "T30041-", - "C31367T", - "T33410-", - "G33447A", - "C38066A", - "C42664T", - "A45990T", - "T48341A", - "T50745C", - "G51355A", - "T51682C", - "G52016A", - "C52389T", - "C52602T", - "G53498A", - "T56271C", - "A71174-", - "G75423A", - "C80549T", - "G81722A", - "A82190C", - "T83083G", - "G87216A", - "C87303T", - "T97494C", - "C100884T", - "C102551A", - "C105412T", - "G105605A", - "G116846A", - "C126632T", - "G126942A", - "A135122G", - "G147239A", - "C148546T", - "T149979C", - "G152105-", - "C162397T", - "C164144T", - "A166358T", - "T169140A", - "C175384T", - "T176564C", - "T183716C", - "T189840C" - ], - "OPG025": [ - "A589T" - ], - "OPG040": [ - "A168X", - "*376X" - ], - "OPG047": [ - "H385X", - "*483X" - ], - "OPG051": [ - "T68M" - ], - "OPG063": [ - "R342H" - ], - "OPG070": [ - "V256I" - ], - "OPG071": [ - "A314V", - "A613T", - "A684T", - "T808M" - ], - "OPG095": [ - "M207I" - ], - "OPG105": [ - "K355N", - "L653R" - ], - "OPG109": [ - "M715I" - ], - "OPG120": [ - "A289T" - ], - "OPG122": [ - "L42I" - ], - "OPG124": [ - "H122Y", - "S186N" - ], - "OPG148": [ - "S216L" - ], - "OPG174": [ - "A284T" - ], - "OPG178": [ - "V199X", - "*205X" - ], - "OPG188": [ - "H268Y" - ], - "OPG189": [ - "A271V" - ], - "OPG191": [ - "Q66H" - ] - }, - "labels": { - "aa": "OPG025: A589T; OPG040: A168X, *376X; OPG047: H385X, *483X; OPG051: T68M; OPG063: R342H; OPG070: V256I; OPG071: A314V, A613T, A684T, T808M; OPG095: M207I; OPG105: K355N, L653R; OPG109: M715I; OPG120: A289T; OPG122: L42I; OPG124: H122Y, S186N; OPG148: S216L; OPG174: A284T; OPG178: V199X, *205X; OPG188: H268Y; OPG189: A271V; OPG191: Q66H" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000025", - "node_attrs": { - "div": 290, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C43A", - "A44T", - "C48-", - "C49-", - "G50-", - "T51-", - "A52-", - "G53-", - "G54-", - "A55-", - "A56-", - "A57-", - "C58-", - "T59-", - "C60-", - "T61-", - "G66A", - "T68A", - "A72G", - "A74T", - "T77-", - "C78-", - "T81A", - "G83T", - "A87T", - "T88A", - "A89C", - "G92C", - "A93T", - "C7089-", - "T7090-", - "T7091-", - "T7092-", - "T7093-", - "A7094-", - "C7095-", - "A7096-", - "T7100-", - "A7101-", - "A7103-", - "C7104-", - "G7105-", - "T7106-", - "T7107-", - "A7108-", - "C8249T", - "C38214T", - "C52909T", - "C63123T", - "C82622T", - "C85325T", - "C85869T", - "C101013T", - "G109883A", - "G117995A", - "A118781G", - "C123585T", - "A125829G", - "G133473T", - "G146819-", - "T146865A", - "A146868T", - "-146877T", - "-146880A", - "C165490T", - "C165639A", - "A184066G", - "G197132-", - "A197133-", - "A197149-", - "G197150-", - "A197151-", - "G197152-", - "T197153-", - "T197154-", - "T197155-", - "C197156-", - "C197157-", - "T197158-", - "A197159-", - "C197160-", - "G197161-", - "G197162-" - ], - "OPG056": [ - "S274N" - ], - "OPG120": [ - "V246M" - ], - "OPG190": [ - "A173D" - ], - "OPG210": [ - "K904R" - ] - }, - "labels": { - "aa": "OPG056: S274N; OPG120: V246M; OPG190: A173D; OPG210: K904R" - } - }, - "children": [ - { - "name": "NODE_0000026", - "node_attrs": { - "div": 292, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T6980-", - "T6981-", - "T6983-", - "T6985-", - "A6986-", - "T6988-", - "T6989-", - "T6991-", - "T7036-", - "T7038-", - "A7039-", - "-7100G", - "-7101T", - "-7103T", - "C133072T", - "-150582G", - "-150583A", - "-150584T", - "-150585G", - "-150586A", - "C159210T", - "G189214A" - ], - "OPG005": [ - "A6T" - ] - }, - "labels": { - "aa": "OPG005: A6T" - } - }, - "children": [ - { - "name": "MT724770", - "node_attrs": { - "div": 292, - "author": { - "author": "Marien,J., Laudisoit,A., Patrono,L.V., Calvignac-Spencer,S., Leendertz,F., Leirs,H., Verheyen,E.", - "value": "Marien,J., Laudisoit,A., Patrono,L.V., Calvignac-Spencer,S., Leendertz,F., Leirs,H., Verheyen,E." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Biology, Universiteit Antwerpen, Belgium" - }, - "date": { - "value": "2014-01-01" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "MT724770" - }, - "strain": { - "value": "MT724770" - }, - "host": { - "value": "Crocidura littoralis" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6978A", - "G6982-", - "G6984-", - "G6987-", - "C6990-", - "G6992-", - "C6993-", - "C6994-", - "C6995-", - "T6996A", - "T7003A", - "A7004C", - "C7005T", - "A7006G", - "A7009G", - "G7012A", - "-7016T", - "-7017T", - "-7018A", - "-7019T", - "-7020T", - "-7021G", - "A7027C", - "C7037-", - "A7041C", - "T7044C", - "A7047T", - "A7048G", - "A7049T", - "G7055A", - "G7056T", - "A7059C", - "G7063A", - "T7065C", - "A7069T", - "C7071G", - "T7074A", - "G7076T", - "T7077C", - "T7079C", - "T7082C", - "T7083A" - ] - } - } - }, - { - "name": "MT724772", - "node_attrs": { - "div": 300, - "author": { - "author": "Marien,J., Laudisoit,A., Patrono,L.V., Calvignac-Spencer,S., Leendertz,F., Leirs,H., Verheyen,E.", - "value": "Marien,J., Laudisoit,A., Patrono,L.V., Calvignac-Spencer,S., Leendertz,F., Leirs,H., Verheyen,E." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Biology, Universiteit Antwerpen, Belgium" - }, - "date": { - "value": "2014-01-01" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "MT724772" - }, - "strain": { - "value": "MT724772" - }, - "host": { - "value": "Funisciurus anerythrus" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-6980T", - "-6981T", - "-6983T", - "-6985T", - "-6986A", - "-6988T", - "-6989T", - "-6991T", - "-7036T", - "-7038T", - "-7039A", - "-18055A", - "-18056C", - "-18057C", - "-39070A", - "A39072T", - "A47966G", - "-146084C", - "-146085G", - "A146865T", - "T146868A", - "-146964A", - "-154351T", - "-154352C", - "G158787T", - "G159351A", - "A160039T", - "T160041A", - "A160042C", - "A188726G", - "-190395T" - ], - "OPG031": [ - "-258G" - ], - "OPG180": [ - "X554S", - "X560*" - ] - }, - "labels": { - "aa": "OPG031: -258G; OPG180: X554S, X560*" - } - } - } - ] - }, - { - "name": "NODE_0000027", - "node_attrs": { - "div": 291, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T7085-", - "T7086-", - "G7087-", - "T7088-", - "G7097-", - "T7098-", - "A7099-", - "T7102-", - "A140105-", - "T140106-", - "A140107-", - "A140108-", - "C140109-", - "A140110-", - "A140111-", - "T140112-", - "T140113-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-", - "T180483A" - ], - "OPG159": [ - "N113X", - "N114-", - "N115-", - "Y116X", - "*146X" - ] - }, - "labels": { - "aa": "OPG159: N113X, N114-, N115-, Y116X, *146X" - } - }, - "children": [ - { - "name": "MN702446", - "node_attrs": { - "div": 294, - "author": { - "author": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A.", - "value": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon" - }, - "date": { - "value": "2018-04-14" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "MN702446" - }, - "strain": { - "value": "MN702446" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Central African Republic" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T6977-", - "G6978-", - "T6979-", - "T6980-", - "T6981-", - "G6982-", - "T6983-", - "G6984-", - "T6985-", - "A6986-", - "G6987-", - "T6988-", - "T6989-", - "C6990-", - "T6991-", - "G6992-", - "C6993-", - "C6994-", - "C6995-", - "C6999A", - "C7002-", - "T7003-", - "A7004-", - "A7015G", - "-7016C", - "-7017T", - "-7018A", - "-7019T", - "-7020C", - "-7021G", - "C7022T", - "A7027C", - "T7036-", - "C7037-", - "T7038-", - "A7039-", - "A7041C", - "T7044C", - "A7047T", - "A7048G", - "A7049T", - "G7055A", - "G7056T", - "A7059C", - "G7063T", - "A7067C", - "C7068A", - "G7070A", - "T7073A", - "T7074C", - "T7077G", - "G7078A", - "G7081-", - "T7082-", - "T7083-", - "T7084-", - "-7087T", - "-7088T", - "-7089C", - "-7090G", - "-7091A", - "-7092T", - "-7093A", - "-7094A", - "-7095C", - "-7096A", - "-7097G", - "-7098C", - "-7099A", - "-7100T", - "-7101T", - "-7102T", - "-7103T", - "-7104A", - "-7105G", - "-7106T", - "-7107T", - "-7108T", - "A8049-", - "G10673T", - "T37115-", - "G42785A", - "-179146A", - "-179147T", - "-179148T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179154C", - "-179155A", - "-179156T", - "-179157T", - "-179158T", - "-179159T", - "-179160A", - "-179161T", - "-179162C", - "-179163C", - "-179164T", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "A181246-", - "C181732G" - ], - "OPG022": [ - "D62E" - ], - "OPG063": [ - "P302S" - ], - "OPG210": [ - "T126S" - ] - }, - "labels": { - "aa": "OPG022: D62E; OPG063: P302S; OPG210: T126S" - } - } - }, - { - "name": "MN702449", - "node_attrs": { - "div": 291, - "author": { - "author": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A.", - "value": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon" - }, - "date": { - "value": "2016-01-02" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "MN702449" - }, - "strain": { - "value": "MN702449" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Central African Republic" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A146865T", - "T146868A", - "T146877A", - "A146880T", - "T197117A", - "C197118G", - "T197121G", - "A197122T", - "T197123A", - "C197127A", - "A197129T", - "T197136A", - "T197138C", - "A197142T", - "C197144T", - "T197166A", - "G197167T" - ] - } - } - }, - { - "name": "NODE_0000028", - "node_attrs": { - "div": 296, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A8049-", - "G18952A", - "G87276A", - "C127584T", - "T148343A", - "A151043G", - "-197132G", - "-197133A", - "-197149A", - "-197150G", - "-197151A", - "-197152G", - "-197153T", - "-197154T", - "-197155T", - "-197156C", - "-197157C", - "-197158T", - "-197159A", - "-197160C", - "-197161G", - "-197162G" - ], - "OPG149": [ - "A130V" - ] - }, - "labels": { - "aa": "OPG149: A130V" - } - }, - "children": [ - { - "name": "MN702444", - "node_attrs": { - "div": 296, - "author": { - "author": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A.", - "value": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon" - }, - "date": { - "value": "2017-02-06" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "MN702444" - }, - "strain": { - "value": "MN702444" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Central African Republic" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MN702445", - "node_attrs": { - "div": 296, - "author": { - "author": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A.", - "value": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon" - }, - "date": { - "value": "2017-02-06" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "MN702445" - }, - "strain": { - "value": "MN702445" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Central African Republic" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "G197006T" - ] - } - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000029", - "node_attrs": { - "div": 268, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G12632A", - "-146877T", - "-146880A" - ], - "OPG023": [ - "A90V" - ] - }, - "labels": { - "aa": "OPG023: A90V" - } - }, - "children": [ - { - "name": "KJ642613", - "node_attrs": { - "div": 280, - "author": { - "author": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Lil,Y., Weil,R.M., Muyembe,J.-J., Kingbeni,P.M., Balilo,M.", - "value": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Lil,Y., Weil,R.M., Muyembe,J.-J., Kingbeni,P.M., Balilo,M." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA" - }, - "date": { - "value": "1970-XX-XX" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "KJ642613" - }, - "strain": { - "value": "KJ642613" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A579-", - "G580-", - "A583G", - "G7469A", - "C8249T", - "G13300A", - "C31628T", - "-41929T", - "T50521-", - "T50522-", - "A50523-", - "T50524-", - "T50525-", - "A50526-", - "C50527-", - "C50528-", - "T50529-", - "G50530-", - "C50531-", - "A50532-", - "T50533-", - "C50534-", - "G58413A", - "G63150A", - "C64611T", - "G66698T", - "C79369T", - "C111519T", - "G133968A", - "C136555T", - "G144316T", - "G150582T", - "A150629-", - "A150630-", - "T178641-", - "T196627-", - "C196628-", - "T196629C" - ], - "OPG083": [ - "V36I" - ], - "OPG153": [ - "M371I" - ] - }, - "labels": { - "aa": "OPG083: V36I; OPG153: M371I" - } - } - }, - { - "name": "NODE_0000030", - "node_attrs": { - "div": 286, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G907A", - "G3308T", - "G11575A", - "T15747-", - "G31211A", - "G35067A", - "G37230T", - "T57906C", - "G60984A", - "G62421A", - "C87507T", - "C100648G", - "T101111C", - "G136039T", - "C137054T", - "A148344T", - "C154681T", - "G180556T", - "G181036A", - "G189591A", - "C193902A", - "C196303T" - ], - "OPG003": [ - "L434I" - ], - "OPG005": [ - "M131I" - ], - "OPG056": [ - "T602N" - ], - "OPG119": [ - "T88R" - ], - "OPG120": [ - "H213R" - ], - "OPG153": [ - "R205H" - ] - }, - "labels": { - "aa": "OPG003: L434I; OPG005: M131I; OPG056: T602N; OPG119: T88R; OPG120: H213R; OPG153: R205H" - } - }, - "children": [ - { - "name": "Congo_2003_358", - "node_attrs": { - "div": 288, - "author": { - "author": "Likos,A.M., Sammons,S.A., Olson,V.A., Frace,A.M., Li,Y., Olsen-Rasmussen,M., Davidson,W., Galloway,R., Khristova,M.L., Reynolds,M.G., Zhao,H., Carroll,D.S., Curns,A., Formenty,P., Esposito,J.J., Regnery,R.L., Damon,I.K., Olsen-Rasmussen,M.S.", - "value": "Likos,A.M., Sammons,S.A., Olson,V.A., Frace,A.M., Li,Y., Olsen-Rasmussen,M., Davidson,W., Galloway,R., Khristova,M.L., Reynolds,M.G., Zhao,H., Carroll,D.S., Curns,A., Formenty,P., Esposito,J.J., Regnery,R.L., Damon,I.K., Olsen-Rasmussen,M.S." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "National Center for Infectious Diseases, Centers for Disease Control and Prevention (US CDC), USA" - }, - "date": { - "value": "2003-XX-XX" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "Congo_2003_358" - }, - "strain": { - "value": "DQ011154" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T136541A", - "G140147A", - "T140154C", - "C150750T", - "C188925A", - "G197006T" - ], - "OPG153": [ - "D376V" - ], - "OPG159": [ - "C127Y" - ] - }, - "labels": { - "aa": "OPG153: D376V; OPG159: C127Y" - } - } - }, - { - "name": "NODE_0000031", - "node_attrs": { - "div": 289, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A5646G", - "T6216-", - "G24996A", - "C149078T", - "A189039-", - "A190991-", - "T191564C" - ], - "NBT03_gp175": [ - "C171R" - ], - "OPG015": [ - "C171R" - ] - }, - "labels": { - "aa": "NBT03_gp175: C171R; OPG015: C171R" - } - }, - "children": [ - { - "name": "Boende_DRC_2008", - "node_attrs": { - "div": 291, - "author": { - "author": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Yoshinori,N., Muyembe,J.-J., Kingbeni,P.M.", - "value": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Yoshinori,N., Muyembe,J.-J., Kingbeni,P.M." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA" - }, - "date": { - "value": "2008-XX-XX" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "Boende_DRC_2008" - }, - "strain": { - "value": "KP849469" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A10459-", - "T10460-", - "A10461T", - "G135460T", - "T136538A", - "G197006T" - ], - "OPG153": [ - "D377V" - ] - }, - "labels": { - "aa": "OPG153: D377V" - } - } - }, - { - "name": "MN702451", - "node_attrs": { - "div": 296, - "author": { - "author": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A.", - "value": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon" - }, - "date": { - "value": "2017-04-14" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "MN702451" - }, - "strain": { - "value": "MN702451" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Central African Republic" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G39626A", - "A65771T", - "G93521T", - "T136535A", - "T146865A", - "A146868T", - "-150568G", - "G151440A", - "G155634-", - "T155635-", - "T155636-", - "A155637-", - "G155638-", - "A155639-", - "T155640-", - "A155641-", - "C165304T", - "C167244T", - "G171695A", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-", - "A179227-", - "T179228-", - "T179229-", - "A179230-", - "T179231-", - "A179232-", - "T179233-", - "A179234T", - "A179236G", - "T197117A", - "C197118G", - "T197123A", - "C197127-", - "G197128-", - "A197129-", - "T197130-", - "T197131-", - "G197132-", - "A197133-", - "T197134-", - "T197135-", - "T197136G", - "C197139T", - "C197143T", - "T197146-", - "C197147-", - "T197148-", - "A197149-", - "G197150-", - "A197151-", - "G197152-", - "T197153-", - "T197154-", - "T197155-", - "C197156-", - "C197157-", - "T197158-", - "A197159-", - "C197160-", - "G197161-", - "G197162-", - "T197163-", - "C197164-", - "G197165-", - "T197166-", - "G197167-", - "G197168-", - "G197169-", - "T197170-", - "C197171-", - "A197172-", - "C197173-", - "A197174-", - "C197175-", - "A197176-", - "T197177-", - "T197178-", - "T197182C" - ], - "OPG153": [ - "D378V" - ], - "OPG192": [ - "H172Y" - ] - }, - "labels": { - "aa": "OPG153: D378V; OPG192: H172Y" - } - } - } - ] - }, - { - "name": "NODE_0000032", - "node_attrs": { - "div": 289, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A134C", - "C33905T", - "G40666C", - "T143617C", - "T146877A", - "A146880T", - "G150582-", - "A150583-", - "T150584-", - "G150585-", - "A150586-", - "T189889-", - "T189890-", - "A189891-", - "T189892-", - "T189893-", - "A189894-", - "C189895-", - "G189896-", - "T189897-", - "G189898-", - "A189899-", - "A189900-", - "G189901-", - "A189902-", - "T189903-", - "G189904-", - "A189905-", - "T189906-", - "A189907-", - "T189908-", - "C189909-", - "A189910-", - "T189911-", - "T189912-", - "A189913-", - "A189914-", - "A189915-", - "C189916-", - "C189917-", - "A189918-", - "A189919-", - "C189920-", - "A189921-", - "T189922-", - "T189923-", - "G189924-", - "A189925-", - "G189926-", - "A189927-", - "T189928-", - "T189929-", - "G189930-", - "G189931-", - "C189932-", - "T189933-", - "C189934-", - "T189935-", - "T189936-", - "A189937-", - "T189938-", - "G189939-", - "T189940-", - "T189941-", - "A189942-", - "G189943-", - "C189944-", - "T189945-", - "G189946-", - "G189947-", - "A189948-", - "T189949-", - "T189950-", - "G189951-", - "A189952-", - "A189953-", - "T189954-", - "T189955-", - "A189956-", - "C189957-", - "T189958-", - "G189959-", - "T189960-", - "A189961-", - "A189962-", - "T189963-", - "A189964-", - "A189965-", - "A189966-", - "T189967-", - "G189968-", - "C189969-", - "A189970-", - "T189971-", - "C189972-", - "G189973-", - "A189974-", - "G189975-", - "T189976-", - "A189977-", - "T189978-", - "A189979-", - "G189980-", - "A189981-", - "G189982-", - "G189983-", - "G189984-", - "A189985-", - "T189986-", - "A189987-", - "T189988-", - "A189989-", - "G189990-", - "C189991-", - "A189992-", - "A189993-", - "T189994-", - "T189995-", - "C189996-", - "T189997-", - "C189998-", - "G189999-", - "A190000-", - "T190001-", - "A190002-", - "A190003-", - "T190004-", - "A190005-", - "G190006-", - "T190007-", - "C190008-", - "A190009-", - "T190010-", - "G190011-", - "C190012-", - "A190013-", - "A190014-", - "T190015-", - "A190016-", - "T190017-", - "T190018-", - "T190019-", - "G190020-", - "A190021-", - "A190022-", - "T190023-", - "G190024-", - "A190025-", - "G190026-", - "A190027-", - "C190028-", - "T190029-", - "G190030-", - "A190031-", - "T190032-", - "A190033-", - "A190034-", - "T190035-", - "T190036-", - "T190037-", - "A190038-", - "G190039-", - "G190040-", - "T190041-", - "A190042-", - "A190043-", - "T190044-", - "A190045-", - "C190046-", - "A190047-", - "G190048-", - "T190049-", - "A190050-", - "C190051-", - "T190052-", - "A190053-", - "C190054-", - "A190055-", - "C190056-", - "A190057-", - "C190058-", - "A190059-", - "T190060-", - "A190061-", - "T190062-", - "C190063-", - "T190064-", - "T190065-", - "T190066-", - "C190067-", - "T190068-", - "A190069-", - "G190070-", - "A190071-", - "T190072-", - "T190073-", - "A190074-", - "T190075-", - "A190076-", - "T190077-", - "A190078-", - "T190079-", - "C190080-", - "G190081-", - "T190082-", - "T190083-", - "A190084-", - "A190085-", - "A190086-", - "A190087-", - "A190088-", - "T190089-", - "C190090-", - "T190091-", - "G190092-", - "T190093-", - "A190094-", - "A190095-", - "G190096-", - "A190097-", - "G190098-", - "G190099-", - "T190100-", - "A190101-", - "T190102-", - "A190103-", - "T190104-", - "T190105-", - "T190106-", - "C190107-", - "T190108-", - "C190109-", - "A190110-", - "T190111-", - "A190112-", - "A190113-", - "G190114-", - "T190115-", - "A190116-", - "T190117-", - "C190118-", - "C190119-", - "A190120-", - "C190121-", - "T190122-", - "G190123-", - "T190124-", - "G190125-", - "T190126-", - "A190127-", - "A190128-", - "T190129-", - "A190130-", - "T190131-", - "T190132-", - "A190133-", - "T190134-", - "T190135-", - "A190136-", - "A190137-", - "T190138-", - "G190139-", - "G190140-", - "A190141-", - "T190142-", - "A190143-", - "T190144-", - "A190145-", - "T190146-", - "A190147-", - "G190148-", - "A190149-", - "T190150-", - "A190151-", - "A190152-", - "C190153-", - "A190154-", - "C190155-", - "A190156-", - "A190157-", - "T190158-", - "A190159-", - "G190160-", - "G190161-", - "G190162-", - "A190163-", - "C190164-", - "T190165-", - "A190166-", - "A190167-", - "T190168-", - "A190169-", - "G190170-", - "T190171-", - "A190172-", - "T190173-", - "T190174-", - "G190175-", - "T190176-", - "A190177-", - "A190178-", - "A190179-", - "A190180-", - "G190181-", - "A190182-", - "T190183-", - "A190184-", - "T190185-", - "A190186-", - "A190187-", - "T190188-", - "C190189-", - "G190190-", - "A190191-", - "C190192-", - "T190193-", - "A190194-", - "T190195-", - "T190196-", - "T190197-", - "G190200-", - "T190201-", - "A190202-", - "C190203-", - "A190204-", - "T190205-", - "A190206-", - "T190207-", - "C190208-", - "C190209-", - "A190210-", - "G190211-", - "A190212-", - "T190213-", - "A190214-", - "T190215-", - "C190216-", - "T190217-", - "A190218-", - "T190219-", - "A190220-", - "T190221-", - "T190222-", - "C190223-", - "C190224-", - "T190225-", - "A190226-", - "C190227-", - "T190228-", - "A190229-", - "G190230-", - "T190231-", - "T190232-", - "T190233-", - "G190234-", - "C190235-", - "T190236-", - "G190237-", - "C190238-", - "G190239-", - "T190240-", - "A190241-", - "G190242-", - "T190243-", - "T190244-", - "G190245-", - "C190246-", - "A190247-", - "T190248-", - "C190249-", - "A190250-", - "T190251-", - "T190252-", - "G190253-", - "A190254-", - "T190255-", - "A190256-", - "T190257-", - "G190258-", - "C190259-", - "A190260-", - "T190261-", - "G190262-", - "A190263-", - "T190264-", - "T190265-", - "T190266-", - "A190267-", - "T190268-", - "C190269-", - "A190270-", - "G190271-", - "G190272-", - "A190273-", - "T190274-", - "T190275-", - "C190276-", - "A190277-", - "G190278-", - "A190279-", - "G190280-", - "A190281-", - "T190282-", - "G190283-", - "A190284-", - "A190285-", - "T190286-", - "T190287-", - "A190288-", - "C190289-", - "T190290-", - "A190291-", - "A190292-", - "G190293-", - "T190294-", - "A190295-", - "A190296-", - "A190297-", - "C190298-", - "T190299-", - "A190300-", - "C190301-", - "A190302-", - "A190303-", - "T190304-", - "C190305-", - "C190306-", - "C190307-", - "A190308-", - "C190309-", - "A190310-", - "A190311-", - "T190312-", - "A190313-", - "A190314-", - "G190315-", - "T190316-", - "A190317-", - "A190318-", - "G190319-", - "A190320-", - "A190321-", - "T190322-", - "C190323-", - "A190324-", - "A190325-", - "A190326-", - "T190327-", - "A190328-", - "T190329-", - "C190330-", - "A190331-", - "A190332-", - "A190333-", - "A190334-", - "A190335-", - "C190336-", - "T190337-", - "C190338-", - "A190339-", - "C190340-", - "T190341-", - "T190342-", - "T190343-", - "T190344-", - "G190345-", - "A190346-", - "T190347-", - "T190348-", - "T190349-", - "T190350-", - "T190351-", - "C190352-", - "T190353-", - "A190354-", - "G190355-", - "T190356-", - "C190357-", - "T190358-", - "T190359-", - "A190360-", - "A190361-", - "G190362-", - "T190363-", - "A190364-", - "A190365-", - "T190366-", - "A190367-", - "C190368-", - "A190369-", - "T190370-", - "A190371-", - "T190372-", - "A190373-", - "T190374-", - "T190375-", - "T190376-", - "A190377-", - "T190378-", - "T190379-", - "A190380-", - "A190381-", - "T190382-", - "A190383-", - "G190384-", - "A190385-", - "C190386-", - "C190387-", - "T190388-", - "A190389-", - "T190390-", - "G190391-", - "A190392-", - "A190393-", - "A190394-", - "T190396-", - "A190397-", - "A190398-", - "A190399-", - "A190400-", - "A190401-", - "A190402-", - "G190403-", - "T190404-", - "T190405-", - "A190406-", - "A190407-", - "C190408-", - "A190409-", - "A190410-", - "T190411-", - "G190412-", - "G190413-", - "A190414-", - "T190415-", - "T190416-", - "C190417-", - "G190418-", - "C190419-", - "G190420-", - "T190421-", - "A190422-", - "T190423-", - "A190424-", - "G190425-", - "C190426-", - "T190427-", - "A190428-", - "T190429-", - "T190430-", - "T190431-", - "A190432-", - "C190433-", - "G190434-", - "T190435-", - "A190436-", - "T190437-", - "T190438-", - "A190439-", - "G190440-", - "T190441-", - "A190442-", - "T190443-", - "C190444-", - "G190445-", - "G190446-", - "C190447-", - "A190448-", - "T190449-", - "C190450-", - "T190451-", - "C190452-", - "T190453-", - "T190454-", - "T190455-", - "T190456-", - "G190457-", - "T190458-", - "A190459-", - "T190460-", - "C190461-", - "T190462-", - "T190463-", - "G190464-", - "T190465-", - "T190466-", - "A190467-", - "A190468-", - "T190469-", - "T190470-", - "G190471-", - "T190472-", - "C190473-", - "A190474-", - "C190475-", - "A190476-", - "A190477-", - "A190478-", - "C190479-", - "T190480-", - "A190481-", - "G190482-", - "T190483-", - "A190484-", - "C190485-", - "A190486-", - "T190487-", - "T190488-", - "A190489-", - "C190490-", - "T190491-", - "T190492-", - "C190493-", - "A190494-", - "A190495-", - "T190496-", - "C190497-", - "T190498-", - "G190499-", - "A190500-", - "A190501-", - "A190502-", - "A190503-", - "T190504-", - "A190505-", - "A190506-", - "A190507-", - "T190508-", - "G190509-", - "G190510-", - "T197076G" - ], - "NBT03_gp174": [ - "M1-", - "D2-", - "S3-", - "R4-", - "I5-", - "A6-", - "I7-", - "Y8-", - "V9-", - "L10-", - "V11-", - "S12-", - "A13-", - "S14-", - "L15-", - "L16-", - "Y17-", - "L18-", - "V19-", - "N20-", - "C21-", - "H22-", - "K23-", - "L24-", - "V25-", - "H26-", - "Y27-", - "F28-", - "N29-", - "L30-", - "K31-", - "I32-", - "N33-", - "G34X", - "*177X" - ], - "OPG052": [ - "A31T" - ] - }, - "labels": { - "aa": "NBT03_gp174: M1-, D2-, S3-, R4-, I5-, A6-, I7-, Y8-, V9-, L10-, V11-, S12-, A13-, S14-, L15-, L16-, Y17-, L18-, V19-, N20-, C21-, H22-, K23-, L24-, V25-, H26-, Y27-, F28-, N29-, L30-, K31-, I32-, N33-, G34X, *177X; OPG052: A31T" - } - }, - "children": [ - { - "name": "NODE_0000033", - "node_attrs": { - "div": 293, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G36971A", - "G124667A", - "G125413A", - "G176109A" - ], - "OPG055": [ - "S38L" - ], - "OPG145": [ - "A241T" - ], - "OPG146": [ - "A76V" - ], - "OPG205": [ - "D152N" - ] - }, - "labels": { - "aa": "OPG055: S38L; OPG145: A241T; OPG146: A76V; OPG205: D152N" - } - }, - "children": [ - { - "name": "DRC 07-0354", - "node_attrs": { - "div": 293, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2007-04-20" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 07-0354" - }, - "strain": { - "value": "JX878425" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-144339G" - ] - } - } - }, - { - "name": "DRC 07-0662", - "node_attrs": { - "div": 293, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2007-09-04" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 07-0662" - }, - "strain": { - "value": "JX878429" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000034", - "node_attrs": { - "div": 292, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T18789C", - "G58263T", - "T73298C" - ], - "OPG031": [ - "T14A" - ] - }, - "labels": { - "aa": "OPG031: T14A" - } - }, - "children": [ - { - "name": "DRC 06-0950", - "node_attrs": { - "div": 294, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2006-10-09" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 06-0950" - }, - "strain": { - "value": "JX878407" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C15207T", - "C47598T" - ], - "OPG025": [ - "A21T" - ] - }, - "labels": { - "aa": "OPG025: A21T" - } - } - }, - { - "name": "NODE_0000035", - "node_attrs": { - "div": 293, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C15349A" - ] - } - }, - "children": [ - { - "name": "DRC 07-0337", - "node_attrs": { - "div": 294, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2007-03-25" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 07-0337" - }, - "strain": { - "value": "JX878423" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C108244T" - ], - "OPG127": [ - "M194I" - ] - }, - "labels": { - "aa": "OPG127: M194I" - } - } - }, - { - "name": "DRC 07-0338", - "node_attrs": { - "div": 293, - "author": { - "author": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G.", - "value": "Kugelman,J.R., Johnston,S.C., Mulembakani,P.M., Kisalu,N., Lee,M.S., Koroleva,G., McCarthy,S.E., Gestole,M.C., Wolfe,N.D., Fair,J.N., Schneider,B.S., Wright,L.L., Huggins,J., Whitehouse,C.A., Wemakoy,E.O., Muyembe-Tamfum,J.J., Hensley,L.E., Palacios,G.F., Rimoin,A.W., Palacios,G." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA" - }, - "date": { - "value": "2007-03-25" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "DRC 07-0338" - }, - "strain": { - "value": "JX878424" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C179226T", - "A179227G", - "A179236G", - "G197006C" - ] - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000036", - "node_attrs": { - "div": 287, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A159953T", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "A179218-", - "C179226-", - "A179227-", - "T179228-", - "T179229-", - "A179230-", - "T179231-", - "A179232-", - "T179233-", - "A179234-", - "A179236G", - "T197076G" - ] - } - }, - "children": [ - { - "name": "NODE_0000037", - "node_attrs": { - "div": 290, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C4584T", - "T55501C", - "T136541A", - "A168328C", - "C179217-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "-179234T" - ], - "OPG074": [ - "Y542C" - ], - "OPG153": [ - "D376V" - ], - "OPG195": [ - "K33N" - ] - }, - "labels": { - "aa": "OPG074: Y542C; OPG153: D376V; OPG195: K33N" - } - }, - "children": [ - { - "name": "MN702452", - "node_attrs": { - "div": 291, - "author": { - "author": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A.", - "value": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon" - }, - "date": { - "value": "2010-08-10" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "MN702452" - }, - "strain": { - "value": "MN702452" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Central African Republic" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C164169T" - ] - } - } - }, - { - "name": "MN702453", - "node_attrs": { - "div": 290, - "author": { - "author": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A.", - "value": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon" - }, - "date": { - "value": "2001-08-11" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "MN702453" - }, - "strain": { - "value": "MN702453" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Central African Republic" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000038", - "node_attrs": { - "div": 288, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G42564A", - "-179218G", - "-179226T" - ] - } - }, - "children": [ - { - "name": "NODE_0000039", - "node_attrs": { - "div": 291, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6372-", - "C6373-", - "C6374-", - "T6375-", - "G6376-", - "A6377-", - "A6378-", - "G6379-", - "T6380-", - "A6381-", - "A6382-", - "T6383-", - "T6384-", - "A6385-", - "A6386-", - "C6387-", - "C6388-", - "A6389-", - "A6390-", - "C6391-", - "T6392-", - "G6393-", - "T6394-", - "T6395-", - "T6396-", - "T6397-", - "T6398-", - "A6399-", - "T6400-", - "T6401-", - "A6402-", - "G6403-", - "T6404-", - "G6405-", - "G6406-", - "C6407-", - "T6408-", - "T6409-", - "T6410-", - "T6411-", - "T6412-", - "T6413-", - "C6414-", - "G6415-", - "A6416-", - "T6417-", - "C6418-", - "T6419-", - "A6420-", - "T6421-", - "C6422-", - "C6423-", - "T6424-", - "C6425-", - "G6426-", - "T6427-", - "C6428-", - "C6431-", - "T6432-", - "C6433-", - "A6434-", - "T6435-", - "C6436-", - "A6437-", - "T6438-", - "C6439-", - "C6440-", - "T6441-", - "T6442-", - "A6443-", - "T6444-", - "A6445-", - "T6446-", - "T6447-", - "A6448-", - "T6449-", - "T6450-", - "A6451-", - "T6452-", - "C6453-", - "A6454-", - "T6455-", - "T6456-", - "A6457-", - "T6458-", - "T6459-", - "A6460-", - "T6461-", - "C6462-", - "A6463-", - "T6464-", - "A6465-", - "G6466-", - "T6467-", - "C6468-", - "T6469-", - "A6470-", - "T6471-", - "T6472-", - "A6473-", - "A6474-", - "A6475-", - "C6476-", - "A6477-", - "C6478-", - "A6479-", - "A6480-", - "A6481-", - "T6482-", - "C6483-", - "A6484-", - "T6485-", - "C6486-", - "T6487-", - "A6488-", - "C6489-", - "G6490-", - "T6491-", - "T6492-", - "T6493-", - "A6494-", - "T6495-", - "A6496-", - "A6497-", - "C6498-", - "A6499-", - "A6500-", - "C6501-", - "A6502-", - "T6503-", - "T6504-", - "C6505-", - "T6506-", - "C6507-", - "A6508-", - "T6509-", - "T6510-", - "A6511-", - "T6512-", - "T6513-", - "A6514-", - "A6515-", - "T6516-", - "T6517-", - "A6518-", - "G6519-", - "T6520-", - "T6521-", - "C6522-", - "T6523-", - "G6524-", - "T6525-", - "A6526-", - "G6527-", - "A6528-", - "A6529-", - "T6530-", - "A6531-", - "T6532-", - "C6533-", - "T6534-", - "T6535-", - "T6536-", - "A6537-", - "A6538-", - "T6539-", - "A6540-", - "A6541-", - "T6542-", - "T6543-", - "T6544-", - "G6545-", - "G6546-", - "C6547-", - "T6548-", - "A6549-", - "T6550-", - "A6551-", - "C6552-", - "A6553-", - "T6554-", - "C6555-", - "T6556-", - "G6557-", - "T6558-", - "T6559-", - "C6560-", - "A6561-", - "A6562-", - "T6563-", - "A6564-", - "C6565-", - "T6566-", - "A6567-", - "T6568-", - "C6569-", - "T6570-", - "A6571-", - "T6572-", - "T6573-", - "G6574-", - "A6575-", - "T6576-", - "G6577-", - "A6578-", - "T6579-", - "T6580-", - "T6581-", - "C6582-", - "T6583-", - "T6584-", - "T6585-", - "T6586-", - "T6587-", - "T6588-", - "A6589-", - "A6590-", - "G6591-", - "A6592-", - "C6593-", - "T6594-", - "T6595-", - "A6596-", - "A6597-", - "A6598-", - "C6599-", - "T6600-", - "A6601-", - "G6602-", - "T6603-", - "T6604-", - "A6605-", - "T6606-", - "G6607-", - "G6608-", - "T6609-", - "A6610-", - "A6611-", - "T6612-", - "G6613-", - "A6614-", - "C6615-", - "G6616-", - "A6617-", - "T6618-", - "G6619-", - "A6620-", - "A6621-", - "A6622-", - "T6623-", - "C6624-", - "G6625-", - "A6626-", - "G6627-", - "T6628-", - "A6629-", - "G6630-", - "T6631-", - "A6632-", - "A6633-", - "C6634-", - "T6635-", - "T6636-", - "C6637-", - "T6638-", - "A6639-", - "A6640-", - "T6641-", - "A6642-", - "A6643-", - "A6644-", - "G6645-", - "A6646-", - "C6647-", - "T6648-", - "T6649-", - "G6650-", - "A6651-", - "T6652-", - "A6653-", - "T6654-", - "C6655-", - "A6656-", - "T6657-", - "T6658-", - "A6659-", - "T6660-", - "C6661-", - "A6662-", - "T6663-", - "A6664-", - "T6665-", - "G6666-", - "T6667-", - "T6668-", - "T6669-", - "G6670-", - "A6671-", - "T6672-", - "C6673-", - "G6674-", - "T6675-", - "C6676-", - "A6677-", - "T6678-", - "A6679-", - "G6680-", - "T6681-", - "T6682-", - "A6683-", - "A6684-", - "T6685-", - "A6686-", - "G6687-", - "T6688-", - "G6689-", - "T6690-", - "G6691-", - "G6692-", - "C6693-", - "T6694-", - "A6695-", - "A6696-", - "A6697-", - "T6698-", - "G6699-", - "G6700-", - "T6701-", - "A6702-", - "C6703-", - "T6704-", - "G6705-", - "T6706-", - "T6707-", - "A6708-", - "A6709-", - "T6710-", - "A6711-", - "A6712-", - "G6713-", - "T6714-", - "T6715-", - "T6716-", - "A6717-", - "T6718-", - "A6719-", - "G6720-", - "A6721-", - "C6722-", - "A6723-", - "A6724-", - "T6725-", - "A6726-", - "T6727-", - "C6728-", - "A6729-", - "T6730-", - "A6731-", - "G6732-", - "C6744-", - "A6745-", - "G6746-", - "A6747-", - "A6748-", - "T6749-", - "T6750-", - "A6751-", - "G6752-", - "A6753-", - "T6754-", - "T6755-", - "A6756-", - "T6757-", - "T6758-", - "T6759-", - "T6760-", - "T6761-", - "T6762-", - "T6763-", - "A6764-", - "A6765-", - "A6766-", - "T6767-", - "A6768-", - "C6769-", - "T6770-", - "G6771-", - "A6772-", - "T6773-", - "C6774-", - "C6775-", - "T6776-", - "C6777-", - "A6778-", - "C6779-", - "A6780-", - "A6781-", - "T6782-", - "T6783-", - "C6784-", - "C6785-", - "G6786-", - "T6787-", - "G6788-", - "A6789-", - "T6790-", - "G6791-", - "T6792-", - "A6793-", - "G6794-", - "C6795-", - "A6796-", - "G6797-", - "T6798-", - "A6799-", - "G6800-", - "T6801-", - "T6802-", - "G6803-", - "G6804-", - "T6805-", - "G6806-", - "C6807-", - "A6808-", - "T6809-", - "G6810-", - "G6811-", - "T6812-", - "C6813-", - "T6814-", - "A6815-", - "T6816-", - "A6817-", - "T6818-", - "C6819-", - "G6820-", - "T6821-", - "T6822-", - "A6823-", - "A6824-", - "A6825-", - "A6826-", - "T6827-", - "G6828-", - "A6835G", - "T6836G", - "G6843T", - "T6846-", - "T6847-", - "C6848-", - "T6849-", - "G6850-", - "A6851-", - "C6852-", - "G6853-", - "T6854-", - "G6855-", - "G6856-", - "A6857-", - "G6858-", - "T6859-", - "A6860-", - "C6861-", - "A6862-", - "G6863-", - "A6864-", - "A6865-", - "T6866-", - "T6867-", - "T6868-", - "T6869-", - "C6870-", - "G6871-", - "A6872-", - "T6873-", - "T6874-", - "A6875-", - "A6876-", - "T6877-", - "G6878-", - "A6879-", - "G6880-", - "T6881-", - "T6882-", - "C6883-", - "A6884-", - "T6885-", - "G6886-", - "G6887-", - "T6888-", - "A6889-", - "A6890-", - "G6891-", - "G6892-", - "A6893-", - "A6894-", - "G6895-", - "G6896-", - "G6897-", - "C6898-", - "A6899-", - "A6900-", - "A6901G", - "A117317G", - "T136535A", - "G150585-", - "G150620A", - "G150621A", - "A150629-", - "A150630-", - "G169718-", - "A169719-", - "T169720-", - "A169721-", - "C169722-", - "A169723-", - "G171695A", - "-173302A", - "-173303T", - "-173304A", - "-173305T", - "G174029A", - "-174525G", - "-174526A", - "-174527T", - "-174528G", - "-174529A", - "-174530A", - "-179216T" - ], - "OPG153": [ - "D378V" - ], - "OPG197": [ - "D17-", - "T18-" - ] - }, - "labels": { - "aa": "OPG153: D378V; OPG197: D17-, T18-" - } - }, - "children": [ - { - "name": "MN702447", - "node_attrs": { - "div": 291, - "author": { - "author": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A.", - "value": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon" - }, - "date": { - "value": "2018-03-20" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "MN702447" - }, - "strain": { - "value": "MN702447" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Central African Republic" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MN702448", - "node_attrs": { - "div": 292, - "author": { - "author": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A.", - "value": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon" - }, - "date": { - "value": "2018-03-07" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "MN702448" - }, - "strain": { - "value": "MN702448" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Central African Republic" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G168741A" - ], - "OPG195": [ - "R171K" - ] - }, - "labels": { - "aa": "OPG195: R171K" - } - } - } - ] - }, - { - "name": "NODE_0000040", - "node_attrs": { - "div": 292, - "clade_membership": { - "value": "I" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G7410A", - "T146860-", - "A146861-", - "T146866-", - "G169138A", - "A171639T", - "G186880A" - ], - "OPG199": [ - "T218S" - ], - "OPG210": [ - "R1842H" - ] - }, - "labels": { - "aa": "OPG199: T218S; OPG210: R1842H" - } - }, - "children": [ - { - "name": "MN702450", - "node_attrs": { - "div": 301, - "author": { - "author": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A.", - "value": "Selekon,B., Labouba,I.L., Gonofio,E.C., Sem Ouilibona,R., Simo Tchetgna,H., Besombes,C., Feher,M., Fontanet,A., Kazanji,M., Manugerra,J.-C., Gessain,A., Nakoune,E., Berthet,N., Nkili Meyong,A." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon" - }, - "date": { - "value": "2016-01-01" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "MN702450" - }, - "strain": { - "value": "MN702450" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Central African Republic" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C6388A", - "G8888A", - "C47932A", - "G100885T", - "G108940A", - "C122824A", - "T136532A", - "T138194A", - "T146862-", - "A146863-", - "T146864-", - "T146865-", - "T146867-", - "A146868-", - "G172951T", - "-179216T", - "A186911G" - ], - "OPG128": [ - "A39V" - ], - "OPG143": [ - "K164N" - ], - "OPG153": [ - "D379V" - ], - "OPG155": [ - "T100S" - ], - "OPG210": [ - "I1852M" - ] - }, - "labels": { - "aa": "OPG128: A39V; OPG143: K164N; OPG153: D379V; OPG155: T100S; OPG210: I1852M" - } - } - }, - { - "name": "MPXV/COD/2023/172V", - "node_attrs": { - "div": 300, - "author": { - "author": "Lee,T.Y., Hwang,Y.-H., Yun,M.-R., Kim,Y.-J., Kim,D.", - "value": "Lee,T.Y., Hwang,Y.-H., Yun,M.-R., Kim,Y.-J., Kim,D." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Korea National Institute of Health, Division of Infectious Disease Vaccine Research" - }, - "date": { - "value": "2022-XX-XX" - }, - "clade_membership": { - "value": "I" - }, - "strain_original": { - "value": "MPXV/COD/2023/172V" - }, - "strain": { - "value": "OQ729808" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A134C", - "G45818A", - "G70364A", - "G111683A", - "C131908A", - "G133359A", - "G139736A", - "-146866G", - "T146877A", - "A146880T", - "T148344A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "G179218A", - "T179226C", - "-179227A", - "-179228T", - "-179229T", - "-179230A", - "-179231T", - "-179232A", - "-179233T", - "-179234A", - "G179236A", - "G188460A" - ], - "OPG089": [ - "D167N" - ], - "OPG130": [ - "P74S" - ], - "OPG158": [ - "R12C" - ] - }, - "labels": { - "aa": "OPG089: D167N; OPG130: P74S; OPG158: R12C" - } - } - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000041", - "node_attrs": { - "div": 306, - "clade_membership": { - "value": "II" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C466T", - "T593-", - "T594-", - "T595-", - "A630C", - "C720T", - "G1093A", - "T1201C", - "G1504A", - "G2086T", - "A2391C", - "C2554T", - "G4836T", - "A5751G", - "G6076A", - "G6146A", - "C7648T", - "C7810T", - "G8066A", - "G8694T", - "C8923T", - "G9161T", - "G9376A", - "A9509T", - "A9698G", - "C10992T", - "G12003A", - "A12324C", - "G12352A", - "G12380A", - "G12418T", - "C13135T", - "A13223C", - "A13348G", - "C13995T", - "T13999G", - "T14091C", - "C14431T", - "A15602G", - "C15794T", - "G16393T", - "G16406A", - "A16581G", - "G16634A", - "T17496C", - "C17800T", - "C18478A", - "C18953T", - "C19290T", - "C19392A", - "C19457T", - "G19475A", - "G20605A", - "G21034A", - "G21191A", - "T22928C", - "G23080T", - "G23171A", - "A23172T", - "G23173A", - "A23175G", - "A23176C", - "G24032A", - "C24179T", - "C25856T", - "C27614T", - "C27949T", - "T28532A", - "G28548A", - "T28710C", - "C29758T", - "G31102A", - "A31144G", - "G32209-", - "A32210-", - "C32211-", - "C32867T", - "A33102T", - "C33656A", - "C33708A", - "C34301A", - "G35613A", - "C36049T", - "T37170C", - "A39072T", - "C39248T", - "G40558T", - "C40565T", - "T40937C", - "T41967C", - "A42516T", - "G42769A", - "C43751T", - "T44972A", - "G45500A", - "G45584A", - "A45637C", - "G46217A", - "C46417T", - "C46427A", - "T47140G", - "C47181T", - "T47735G", - "G49223T", - "T49994C", - "A50595C", - "G52354T", - "C52684T", - "C52938T", - "A52989C", - "G53156A", - "A53257G", - "C55188T", - "G55203A", - "C56531T", - "G58035T", - "C58131T", - "C58965T", - "G59046A", - "T59488C", - "G59709A", - "G60874C", - "C61056A", - "C62823T", - "C63156T", - "C63303T", - "A63976G", - "G64465A", - "A65352T", - "G65663A", - "G66263A", - "C66761A", - "C67245T", - "C67550T", - "T69675G", - "G72261A", - "G73076A", - "G75790A", - "C76123T", - "G76198A", - "G76648A", - "G76911A", - "C78461A", - "G78641A", - "G78942A", - "T79267C", - "A79502C", - "G79829A", - "T81989C", - "C83360T", - "C83843T", - "G84395A", - "T85763C", - "T86502G", - "T87584C", - "G88773A", - "G90493A", - "C90891T", - "G91347A", - "G91489T", - "C93356T", - "C95469T", - "T96651C", - "A97572G", - "A99234G", - "C100341T", - "A102971C", - "G103051A", - "G103424T", - "C106857A", - "G107511T", - "G108793A", - "G110828T", - "C111539T", - "G111545A", - "T111591A", - "A113747G", - "G114458A", - "C116583T", - "T116643A", - "A117014G", - "G117725T", - "C118520T", - "A120174C", - "C120363T", - "G121082A", - "A121453C", - "G121711A", - "C122049T", - "A122422G", - "C124687T", - "A125047G", - "G125334A", - "G125556A", - "G126923T", - "C126969T", - "C127859T", - "G128546T", - "G130030A", - "C131806T", - "C132118T", - "C133280T", - "G133328A", - "G133455A", - "T134233A", - "G134491A", - "C134765T", - "G136190T", - "C136486A", - "G136596A", - "G137026T", - "C137377T", - "C137731T", - "G137925A", - "C138513T", - "A138654G", - "C138746T", - "G139285T", - "C139539T", - "G139771A", - "C139874T", - "A140105-", - "T140106-", - "A140107-", - "A140108-", - "C140109-", - "A140110-", - "A140111-", - "T140112-", - "T140113-", - "G143108A", - "C143392T", - "T143997C", - "C144049T", - "C145074T", - "G145088T", - "C145336T", - "G145523T", - "C145551A", - "T146098G", - "G146215A", - "G146434A", - "T146446C", - "G147904T", - "T150132C", - "A150153G", - "C150488T", - "C150513T", - "G150545-", - "G150780A", - "G151320A", - "A151341C", - "G151923A", - "A152967T", - "G153645A", - "T154702C", - "T154975C", - "A155479C", - "G155843A", - "A158166-", - "G158787T", - "G159351A", - "C159530T", - "T159741C", - "G159780A", - "T160924A", - "T161519A", - "T162639C", - "G162720A", - "A165006G", - "T165691C", - "T166655-", - "T166656-", - "C166934T", - "C168185T", - "C168588-", - "T168769C", - "A168987C", - "G169081A", - "C169142T", - "G169353A", - "A169721-", - "C170037T", - "G170335A", - "A172087-", - "G172304A", - "G173102A", - "G173472A", - "T173569C", - "G173974A", - "A174301G", - "G174519-", - "A174520-", - "T174521-", - "G174522-", - "A174523-", - "A174524-", - "T175964C", - "T176453C", - "A176701G", - "A176715G", - "C177517T", - "C177724T", - "C178237T", - "C178311A", - "A178639G", - "A178791G", - "A179023G", - "T179226C", - "T179478C", - "C179538A", - "T179589G", - "C179690T", - "C180197T", - "A181364T", - "C182033T", - "C182348A", - "G183491A", - "C183718T", - "C183920T", - "C184286T", - "A185268G", - "G185762A", - "C185900T", - "C186077T", - "G186466T", - "G186505A", - "A187080-", - "C187345T", - "G187498A", - "C187839T", - "A187914G", - "C187964T", - "C188537T", - "A188726G", - "C188747A", - "G188812A", - "A189179T", - "C189909A", - "A190154G", - "T190396A", - "T190404G", - "G190596T", - "T190648A", - "G191051A", - "C191064T", - "A191401G", - "T191459C", - "C192374A", - "T192471C", - "T194819G", - "C195124A", - "C195706T", - "A196009G", - "C196117T", - "G196490A", - "A196601-", - "A196602-", - "A196603-", - "G196744A" - ], - "NBT03_gp174": [ - "A63S", - "V80E" - ], - "NBT03_gp175": [ - "A4V", - "F136L" - ], - "OPG002": [ - "S121A" - ], - "OPG015": [ - "A4V", - "F136L" - ], - "OPG021": [ - "I38V" - ], - "OPG023": [ - "A174V", - "S193A", - "H300Y", - "E637K" - ], - "OPG024": [ - "G32S" - ], - "OPG025": [ - "K393E", - "V425I" - ], - "OPG029": [ - "R146C" - ], - "OPG030": [ - "D12N", - "N113S" - ], - "OPG031": [ - "E117D" - ], - "OPG034": [ - "R205L" - ], - "OPG036": [ - "P11S" - ], - "OPG037": [ - "R415C" - ], - "OPG038": [ - "P27H", - "I78V" - ], - "OPG043": [ - "A3T" - ], - "OPG044": [ - "L148M" - ], - "OPG045": [ - "T185A" - ], - "OPG049": [ - "V17E", - "R314X", - "H315X", - "*319X" - ], - "OPG056": [ - "Y622C" - ], - "OPG059": [ - "L26I" - ], - "OPG063": [ - "A307V" - ], - "OPG064": [ - "S88A" - ], - "OPG065": [ - "D23N" - ], - "OPG066": [ - "R83K", - "N97H" - ], - "OPG068": [ - "E341D" - ], - "OPG071": [ - "T428I", - "S484A", - "V501I" - ], - "OPG074": [ - "D199N" - ], - "OPG079": [ - "Y45C" - ], - "OPG080": [ - "E321D", - "S382C" - ], - "OPG084": [ - "T211S" - ], - "OPG085": [ - "A328T", - "V591F" - ], - "OPG096": [ - "M68I" - ], - "OPG100": [ - "Q152K" - ], - "OPG101": [ - "A153T" - ], - "OPG102": [ - "V249I" - ], - "OPG109": [ - "T622A" - ], - "OPG111": [ - "V77I" - ], - "OPG112": [ - "R34H" - ], - "OPG130": [ - "A122T" - ], - "OPG135": [ - "E90V" - ], - "OPG145": [ - "R463Q" - ], - "OPG148": [ - "S313I" - ], - "OPG150": [ - "E256D" - ], - "OPG153": [ - "H358Y", - "P493Q" - ], - "OPG154": [ - "R107H" - ], - "OPG156": [ - "S42Y", - "A222T" - ], - "OPG157": [ - "V24M" - ], - "OPG159": [ - "A2T", - "S36L", - "N113X", - "N114-", - "N115-", - "Y116X", - "*146X" - ], - "OPG164": [ - "V111I" - ], - "OPG165": [ - "L161S" - ], - "OPG167": [ - "S107Y", - "V112I" - ], - "OPG170": [ - "I111M" - ], - "OPG172": [ - "D160Y" - ], - "OPG176": [ - "S227L" - ], - "OPG178": [ - "V139I" - ], - "OPG185": [ - "T205I" - ], - "OPG187": [ - "*300K" - ], - "OPG191": [ - "Y165X", - "F166X", - "*169X" - ], - "OPG195": [ - "S120X", - "*222X" - ], - "OPG197": [ - "T18X", - "*101X" - ], - "OPG198": [ - "V100I" - ], - "OPG200": [ - "G52D" - ], - "OPG205": [ - "Y349C", - "S354G", - "A621V", - "A690V" - ], - "OPG208": [ - "T142I", - "A311V" - ], - "OPG210": [ - "L3F", - "N331K", - "A788V", - "T1305A", - "R1704L", - "G1717D" - ] - }, - "labels": { - "aa": "NBT03_gp174: A63S, V80E; NBT03_gp175: A4V, F136L; OPG002: S121A; OPG015: A4V, F136L; OPG021: I38V; OPG023: A174V, S193A, H300Y, E637K; OPG024: G32S; OPG025: K393E, V425I; OPG029: R146C; OPG030: D12N, N113S; OPG031: E117D; OPG034: R205L; OPG036: P11S; OPG037: R415C; OPG038: P27H, I78V; OPG043: A3T; OPG044: L148M; OPG045: T185A; OPG049: V17E, R314X, H315X, *319X; OPG056: Y622C; OPG059: L26I; OPG063: A307V; OPG064: S88A; OPG065: D23N; OPG066: R83K, N97H; OPG068: E341D; OPG071: T428I, S484A, V501I; OPG074: D199N; OPG079: Y45C; OPG080: E321D, S382C; OPG084: T211S; OPG085: A328T, V591F; OPG096: M68I; OPG100: Q152K; OPG101: A153T; OPG102: V249I; OPG109: T622A; OPG111: V77I; OPG112: R34H; OPG130: A122T; OPG135: E90V; OPG145: R463Q; OPG148: S313I; OPG150: E256D; OPG153: H358Y, P493Q; OPG154: R107H; OPG156: S42Y, A222T; OPG157: V24M; OPG159: A2T, S36L, N113X, N114-, N115-, Y116X, *146X; OPG164: V111I; OPG165: L161S; OPG167: S107Y, V112I; OPG170: I111M; OPG172: D160Y; OPG176: S227L; OPG178: V139I; OPG185: T205I; OPG187: *300K; OPG191: Y165X, F166X, *169X; OPG195: S120X, *222X; OPG197: T18X, *101X; OPG198: V100I; OPG200: G52D; OPG205: Y349C, S354G, A621V, A690V; OPG208: T142I, A311V; OPG210: L3F, N331K, A788V, T1305A, R1704L, G1717D", - "clade": "clade II" - } - }, - "children": [ - { - "name": "NODE_0000042", - "node_attrs": { - "div": 393, - "clade_membership": { - "value": "IIa" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G580T", - "C4693-", - "T4694-", - "T4695-", - "C6433T", - "C6439T", - "A6448T", - "C6453A", - "A6475T", - "A6481G", - "C6483A", - "C6486G", - "A6494T", - "C6501G", - "C6505T", - "G6519T", - "T6521A", - "G6524T", - "T6525A", - "C6533T", - "A6538G", - "C6547A", - "C6552T", - "G6557T", - "T6581A", - "A6590T", - "G6591T", - "T6594C", - "C6599T", - "G6602A", - "G6607C", - "G6613A", - "A6620G", - "G6625C", - "T6635A", - "T6641G", - "A6644G", - "C6647T", - "T6648A", - "G6650A", - "T6654A", - "C6661A", - "G6666T", - "T6667C", - "C6673A", - "G6674T", - "T6675C", - "T6681C", - "A6684T", - "A6686C", - "G6687T", - "T6688G", - "C6693A", - "T6698A", - "G6699A", - "A6702G", - "C6703T", - "T6704A", - "T6707G", - "A6709G", - "T6714A", - "T6715G", - "C6722G", - "A6724G", - "T6725C", - "C6728G", - "A6747C", - "T6750A", - "A6764C", - "A6766T", - "A6768T", - "T6776A", - "A6778G", - "T6787A", - "T6792C", - "G6794T", - "G6797A", - "T6801A", - "T6805C", - "A6808T", - "G6810T", - "G6811C", - "T6821A", - "T6822G", - "A6835C", - "T6836A", - "A6837G", - "A6839C", - "T6841C", - "A6842G", - "T6845A", - "G6853A", - "T6854G", - "G6858C", - "C6861T", - "T6866A", - "G6871C", - "T6882C", - "A6884T", - "A6890T", - "G6896A", - "G6897A", - "C6898A", - "G6903A", - "A6913T", - "A6916-", - "C6919A", - "A6920C", - "G6924C", - "T6925A", - "T6926A", - "A6927C", - "A6928C", - "A6930T", - "T6932G", - "T6936C", - "T6945G", - "A6953T", - "C6955T", - "A6958T", - "A6959T", - "A6964C", - "A6965T", - "T6980A", - "G6982A", - "T6989A", - "C6994A", - "C6995G", - "T7001A", - "A7004G", - "C7018A", - "C7020A", - "C7022A", - "C7026G", - "A7027C", - "T7029A", - "C7037G", - "T7043G", - "C7046T", - "C7050A", - "T7058A", - "C7062G", - "G7063T", - "T7065G", - "C7068-", - "T7075C", - "G7078A", - "A7576-", - "C7864T", - "T8015C", - "A8048-", - "A8143G", - "T8494-", - "G8841A", - "T8992-", - "T9054C", - "A11365G", - "C11745T", - "G12947A", - "C18109T", - "T19324A", - "A21107-", - "G22308A", - "C23190T", - "C23747T", - "G23966A", - "G24232-", - "C24233-", - "A24234-", - "C24977T", - "C25368-", - "C29203A", - "C30510T", - "G30699T", - "C31454A", - "G32326A", - "A33193-", - "T33409-", - "C35859T", - "C36732T", - "A42426G", - "A54013G", - "G55750A", - "G58482T", - "A70398C", - "G76393A", - "G77451A", - "C79658T", - "G80435T", - "G84373A", - "C85145T", - "A86916G", - "G87055A", - "C89607T", - "G89869A", - "G90034A", - "A91245-", - "A91246-", - "A91247-", - "T91248-", - "G91249-", - "G91250-", - "G91737A", - "G93422A", - "G94404T", - "G97371A", - "C99287T", - "G99587A", - "G100967A", - "A104985G", - "G106460T", - "G107366T", - "G125514T", - "T130846C", - "A131548G", - "T132811-", - "T133078-", - "T133079-", - "T133080-", - "T133081-", - "T133082-", - "T133083-", - "T133084-", - "T133085-", - "T133086-", - "T133087-", - "T133088-", - "T133089-", - "T133090-", - "C133164-", - "A133165-", - "A133166-", - "T133167-", - "C133168-", - "T133169-", - "T133170-", - "T133171-", - "C133172-", - "T133173-", - "C133539T", - "G133682A", - "G136446A", - "T136641C", - "A137515G", - "G140772A", - "G142337A", - "T146855-", - "A146856-", - "T146857-", - "T146858-", - "T146859-", - "T146860-", - "A146861-", - "A147926T", - "A148124G", - "C148542T", - "T150544-", - "T150546-", - "G150547-", - "A150548-", - "A150549-", - "G150550-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G150568-", - "A150569-", - "T150570-", - "A150571-", - "T150572-", - "G150573-", - "A150574-", - "T150575-", - "G150576-", - "G150577-", - "A150578-", - "T150579-", - "A150580-", - "T150581-", - "G150582-", - "A150583-", - "T150584-", - "G150585-", - "A150586-", - "T150592-", - "C153210A", - "G153894A", - "C156081T", - "C156162A", - "C156414-", - "A156415-", - "G156448A", - "A156546-", - "G156547-", - "C157280T", - "A157672-", - "T157673-", - "G157674-", - "A157675-", - "T157676-", - "A157677-", - "A157678-", - "A157679-", - "A157680-", - "A157681-", - "T157682-", - "T157683-", - "T157684-", - "T157685-", - "A157686-", - "A157687-", - "G157688-", - "C157689-", - "G157690-", - "A158027-", - "T158028-", - "A158029-", - "C158981T", - "G159964T", - "C160120T", - "G161760A", - "A166091-", - "A166092-", - "T166093-", - "A166094-", - "A166095-", - "T166096-", - "T166097-", - "A166098-", - "A166099-", - "T166100-", - "A166101-", - "A166102-", - "T166103-", - "T166104-", - "T168442-", - "A168443-", - "A169574G", - "-169721T", - "A169763-", - "C169764-", - "A169765-", - "A169767-", - "G169772A", - "A169809-", - "A169810-", - "G169811-", - "G170283A", - "G170914-", - "G171068A", - "T172524C", - "T172661-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "A173300-", - "T173301-", - "A173302-", - "T173303-", - "A173304-", - "T173305-", - "A173306-", - "T173307-", - "A173308-", - "T173309-", - "A173310-", - "T173311-", - "A173312-", - "T173313-", - "A173314-", - "T173315-", - "A173316-", - "T173317-", - "G173318-", - "T173498-", - "A173499-", - "G173544A", - "G173641A", - "T173740-", - "G175396A", - "A177073G", - "C178285T", - "T179072-", - "G179076-", - "C179423T", - "A180470-", - "A180471-", - "A180472-", - "A180473-", - "A180474-", - "T180475-", - "T180476-", - "G181076A", - "T181102-", - "A181103-", - "T181104-", - "A181105-", - "T181106-", - "T181107-", - "C181108-", - "C181109-", - "T181110-", - "C182411A", - "C182600T", - "C183466A", - "-187080T", - "G187398-", - "T187399-", - "A187400-", - "C187401-", - "C189273T", - "T189739-", - "A192515-", - "A192516-", - "G192517-", - "C196630A", - "A197082G" - ], - "OPG023": [ - "D386N" - ], - "OPG037": [ - "*443X" - ], - "OPG040": [ - "E37X", - "A168T", - "*376X" - ], - "OPG045": [ - "E20D" - ], - "OPG047": [ - "L166I", - "D229N" - ], - "OPG049": [ - "P276S" - ], - "OPG050": [ - "F72X", - "*76X" - ], - "OPG055": [ - "A118T" - ], - "OPG074": [ - "S459F" - ], - "OPG089": [ - "E178A" - ], - "OPG102": [ - "H192Y" - ], - "OPG105": [ - "S1083N" - ], - "OPG108": [ - "A2V" - ], - "OPG110": [ - "V80I", - "A135T" - ], - "OPG112": [ - "M1-", - "E2X", - "*147X" - ], - "OPG113": [ - "A3T" - ], - "OPG118": [ - "A281V", - "G381D" - ], - "OPG120": [ - "A261V" - ], - "OPG123": [ - "V29A" - ], - "OPG125": [ - "H97N", - "L399I" - ], - "OPG153": [ - "T343A", - "H408Y" - ], - "OPG163": [ - "V46I" - ], - "OPG172": [ - "D167V" - ], - "OPG173": [ - "T30A" - ], - "OPG174": [ - "C285Y" - ], - "OPG185": [ - "T22I" - ], - "OPG195": [ - "V71X", - "I72X" - ], - "OPG197": [ - "X18S", - "T32-", - "D33X", - "D35N", - "K47X", - "E48X" - ], - "OPG204": [ - "E289K" - ], - "OPG205": [ - "H473R" - ], - "OPG208": [ - "T53I" - ], - "OPG209": [ - "G187R" - ], - "OPG210": [ - "S704Y" - ] - }, - "labels": { - "aa": "OPG023: D386N; OPG037: *443X; OPG040: E37X, A168T, *376X; OPG045: E20D; OPG047: L166I, D229N; OPG049: P276S; OPG050: F72X, *76X; OPG055: A118T; OPG074: S459F; OPG089: E178A; OPG102: H192Y; OPG105: S1083N; OPG108: A2V; OPG110: V80I, A135T; OPG112: M1-, E2X, *147X; OPG113: A3T; OPG118: A281V, G381D; OPG120: A261V; OPG123: V29A; OPG125: H97N, L399I; OPG153: T343A, H408Y; OPG163: V46I; OPG172: D167V; OPG173: T30A; OPG174: C285Y; OPG185: T22I; OPG195: V71X, I72X; OPG197: X18S, T32-, D33X, D35N, K47X, E48X; OPG204: E289K; OPG205: H473R; OPG208: T53I; OPG209: G187R; OPG210: S704Y", - "clade": "clade IIa" - } - }, - "children": [ - { - "name": "NODE_0000043", - "node_attrs": { - "div": 472, - "clade_membership": { - "value": "IIa" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C334T", - "T596-", - "T597-", - "T598-", - "T599-", - "T600-", - "C3299A", - "G4723T", - "C4725T", - "T4726A", - "T4727A", - "G4755T", - "C4757T", - "T4758A", - "T4759A", - "G7610A", - "T8335-", - "T10992C", - "C11237A", - "G12496T", - "G13465C", - "T16524C", - "G20501T", - "G22164A", - "C22169T", - "A23203G", - "A23289T", - "-25368A", - "A32972C", - "T33806C", - "T37110C", - "G40684T", - "T45966A", - "A45969-", - "T45970-", - "T45979-", - "T47499A", - "C50255T", - "G55330T", - "G64427A", - "C66773T", - "G71925A", - "C77775A", - "A78461C", - "A80583C", - "G83661A", - "A84278G", - "G88566T", - "C92630A", - "G103421A", - "C107921T", - "T108250C", - "C113843T", - "T125262C", - "G132531A", - "A133442G", - "C134489T", - "C135792T", - "C136794T", - "G138298A", - "C141072T", - "G141294A", - "G144604A", - "T147634G", - "T150587-", - "A150588-", - "T150589-", - "G150590-", - "A150591-", - "G150593-", - "G150594-", - "A150595-", - "T150601A", - "G155105A", - "C155392T", - "T156215C", - "T156724-", - "G159963A", - "C160171T", - "G161470A", - "T162663G", - "A162722G", - "G163020T", - "C163836T", - "G165637T", - "T168345A", - "A168370-", - "A168371-", - "C168372-", - "T168373-", - "G168374-", - "A168375-", - "T168376-", - "T168377-", - "G168378-", - "C168379-", - "A168380-", - "G168381-", - "T168382-", - "G168383-", - "T168384-", - "T168385-", - "C168386-", - "A168387-", - "T168388-", - "C168389-", - "G168390-", - "C168391-", - "C168392-", - "C168393-", - "A168394-", - "A168395-", - "C168396-", - "T168397-", - "G168398-", - "C168399-", - "A168400-", - "A168401-", - "G168402-", - "T168403-", - "G168404-", - "G168405-", - "A168406-", - "G168407-", - "G168408-", - "A168409-", - "T168410-", - "T168411-", - "G168412-", - "A168413-", - "T168414-", - "A168415-", - "A168416-", - "C168417-", - "T168418-", - "G168419-", - "A168420-", - "A168421-", - "G168422-", - "G168423-", - "C168424-", - "A168425-", - "A168426-", - "T168427-", - "G168428-", - "G168429-", - "A168430-", - "T168431-", - "T168432-", - "C168433-", - "A168434-", - "G168435-", - "A168436-", - "G168437-", - "T168438-", - "A168439-", - "G168440-", - "T168441-", - "T168444-", - "A168445-", - "T168446-", - "A168447-", - "T168448-", - "G168449-", - "A168450-", - "T168451-", - "C168452-", - "A168453-", - "A168454-", - "T168455-", - "G168456-", - "T168457-", - "A168458-", - "C168459-", - "A168460-", - "G168461-", - "A168462-", - "A168463-", - "C168464-", - "C168465-", - "C168466-", - "C168467-", - "A168468-", - "T168469-", - "G168470-", - "A168471-", - "C168472-", - "T168473-", - "T168474-", - "T168475-", - "A168476-", - "T168477-", - "T168478-", - "A168479-", - "T168480-", - "C168481-", - "A168482-", - "C168483-", - "C168484-", - "G168485-", - "A168486-", - "T168487-", - "A168488-", - "C168489-", - "T168490-", - "C168491-", - "A168492-", - "A168493-", - "C168494-", - "A168495-", - "A168496-", - "A168497-", - "C168498-", - "A168499-", - "C168500-", - "G168501-", - "T168502-", - "C168503-", - "T168504-", - "T168505-", - "G168506-", - "G168507-", - "A168508-", - "T168509-", - "C168510-", - "A168511-", - "T168512-", - "C168513-", - "T168514-", - "C168515-", - "A168516-", - "T168517-", - "A168518-", - "C168519-", - "A168520-", - "T168521-", - "A168522-", - "T168523-", - "A168524-", - "T168525-", - "T168526-", - "A168527-", - "A168528-", - "A168529-", - "T168530-", - "T168531-", - "C168532-", - "A168533-", - "G168534-", - "T168535-", - "A168536-", - "A168537-", - "C168538-", - "A168539-", - "T168540-", - "G168541-", - "A168542-", - "A168543-", - "T168544-", - "A168545-", - "C168546-", - "A168547-", - "G168548-", - "G168549-", - "T168550-", - "G168551-", - "T168552-", - "C168553-", - "C168554-", - "C168555-", - "A168556-", - "T168557-", - "C168558-", - "T168559-", - "A168560-", - "G168561-", - "T168562-", - "A168563-", - "T168564-", - "T168565-", - "C168566-", - "C168567-", - "A168568-", - "A168569-", - "A168570-", - "A168571-", - "T168572-", - "G168573-", - "T168574-", - "T168575-", - "C168576-", - "C168577-", - "A168578-", - "G168579-", - "A168580-", - "A168581-", - "C168582-", - "T168583-", - "C168584-", - "T168585-", - "C168586-", - "T168587-", - "T168589-", - "A168590-", - "T168591-", - "T168592-", - "T168593-", - "C168594-", - "T168595-", - "G168596-", - "T168597-", - "A168598-", - "T168599-", - "A168600-", - "T168601-", - "T168602-", - "G168603-", - "T168604-", - "G168605-", - "A168606-", - "T168607-", - "C168608-", - "A168609-", - "A168610-", - "G168611-", - "A168612-", - "G168613-", - "G168614-", - "C168615-", - "G168616-", - "G168617-", - "G168618-", - "A168619-", - "G168620-", - "A168621-", - "C168622-", - "A168623-", - "T168624-", - "A168625-", - "A168626-", - "A168627-", - "A168628-", - "T168629-", - "T168630-", - "T168631-", - "G168632-", - "A168633-", - "G168634-", - "G168635-", - "A168636-", - "G168637-", - "T168638-", - "A168639-", - "T168640-", - "A168641-", - "C168642-", - "T168643-", - "C168644-", - "A168645-", - "A168646-", - "G168647-", - "A168648-", - "A168649-", - "T168650-", - "C168651-", - "A168652-", - "A168653-", - "G168654-", - "T168655-", - "G168656-", - "A168657-", - "T168658-", - "A168659-", - "T168660-", - "C168661-", - "A168662-", - "G168663-", - "T168664-", - "A168665-", - "T168666-", - "T168667-", - "A168668-", - "G168669-", - "A168670-", - "G168671-", - "T168672-", - "T168673-", - "A168674-", - "A168675-", - "G168676-", - "T168677-", - "A168678-", - "T168679-", - "G168680-", - "A168681-", - "T168682-", - "T168683-", - "C168684-", - "A168685-", - "T168686-", - "C168687-", - "A168688-", - "T168689-", - "G168690-", - "T168691-", - "A168692-", - "T168693-", - "T168694-", - "G168695-", - "A168696-", - "T168697-", - "T168698-", - "A168699-", - "T168700-", - "C168701-", - "T168702-", - "G168703-", - "G168704-", - "G168705-", - "T168706-", - "A168707-", - "T168708-", - "T168709-", - "A168710-", - "A168711-", - "T168712-", - "C168713-", - "A168714-", - "A168715-", - "A168716-", - "G168717-", - "T168718-", - "T168719-", - "T168720-", - "C168721-", - "A168722-", - "T168723-", - "G168724-", - "A168725-", - "A168726-", - "T168727-", - "G168728-", - "A168729-", - "A168730-", - "T168731-", - "G168732-", - "T168733-", - "A168734-", - "T168735-", - "T168736-", - "C168737-", - "G168738-", - "A168739-", - "A168740-", - "G168741-", - "A168742-", - "A168743-", - "T168744-", - "T168745-", - "A168746-", - "C168747-", - "A168748-", - "A168749-", - "C168750-", - "A168751-", - "T168752-", - "G168753-", - "G168754-", - "G168755-", - "A168756-", - "T168757-", - "A168758-", - "G168759-", - "A168760-", - "G168761-", - "A168762-", - "A168763-", - "T168764-", - "C168765-", - "A168766-", - "T168767-", - "G168768-", - "C168769-", - "G168770-", - "T168771-", - "C168772-", - "A168773-", - "G168774-", - "A168775-", - "A168776-", - "T168777-", - "T168778-", - "G168779-", - "A168780-", - "T168781-", - "A168782-", - "C168783-", - "A168784-", - "C168785-", - "A168786-", - "G168787-", - "A168788-", - "C168789-", - "T168790-", - "A168791-", - "T168792-", - "A168793-", - "A168794-", - "A168795-", - "T168796-", - "A168797-", - "A168798-", - "A168799-", - "T168800-", - "A168801-", - "T168802-", - "C168803-", - "T168804-", - "T168805-", - "A168806-", - "A168807-", - "G168808-", - "T168809-", - "C168810-", - "T168811-", - "T168812-", - "G168813-", - "C168814-", - "A168815-", - "C168816-", - "C168817-", - "A168818-", - "A168819-", - "C168820-", - "A168821-", - "C168822-", - "A168823-", - "A168824-", - "A168825-", - "A168826-", - "T168827-", - "T168828-", - "C168829-", - "G168830-", - "A168831-", - "C168832-", - "C168833-", - "G168834-", - "T168835-", - "A168836-", - "A168837-", - "T168838-", - "G168839-", - "T168840-", - "C168841-", - "T168842-", - "A168843-", - "C168844-", - "A168845-", - "A168846-", - "A168847-", - "A168848-", - "G168849-", - "G168850-", - "T168851-", - "C168945T", - "-169767T", - "T170754C", - "G172736A", - "C173569T", - "C174990T", - "C175537T", - "C178666T", - "-179072A", - "-179076T", - "C180258T", - "A180469-", - "C181298T", - "T183552A", - "C187489T", - "G187888A", - "C188575T", - "C189627A", - "A192451T", - "A192452T", - "G192453A", - "C192455A", - "A192483T", - "A192484T", - "G192485A", - "C192487A", - "G193911T", - "A196604-", - "A196605-", - "A196606-", - "A196607-", - "A196608-", - "G196876A" - ], - "OPG003": [ - "D437Y" - ], - "OPG019": [ - "A11T" - ], - "OPG023": [ - "N135K", - "R555L", - "K637E" - ], - "OPG025": [ - "N601K" - ], - "OPG037": [ - "V89M" - ], - "OPG039": [ - "V277D" - ], - "OPG040": [ - "X37D", - "X376*" - ], - "OPG052": [ - "K64E" - ], - "OPG074": [ - "T599N" - ], - "OPG083": [ - "T97M" - ], - "OPG085": [ - "V587M" - ], - "OPG099": [ - "F37L" - ], - "OPG100": [ - "K152Q" - ], - "OPG105": [ - "V846I" - ], - "OPG109": [ - "D294E" - ], - "OPG145": [ - "M439T" - ], - "OPG153": [ - "A292T" - ], - "OPG155": [ - "T65I" - ], - "OPG160": [ - "M1I" - ], - "OPG161": [ - "A65T" - ], - "OPG172": [ - "S70A" - ], - "OPG181": [ - "A232T" - ], - "OPG188": [ - "N356K", - "Q376R" - ], - "OPG195": [ - "I39N", - "R47X", - "T48-", - "D49-", - "C50-", - "S51-", - "V52-", - "H53-", - "R54-", - "P55-", - "T56-", - "A57-", - "S58-", - "G59-", - "G60-", - "L61-", - "I62-", - "T63-", - "E64-", - "G65-", - "N66-", - "G67-", - "F68-", - "R69-", - "V70-", - "X71-", - "X72-", - "Y73-", - "D74-", - "Q75-", - "C76-", - "T77-", - "E78-", - "P79-", - "H80-", - "D81-", - "F82-", - "I83-", - "I84-", - "T85-", - "D86-", - "T87-", - "Q88-", - "Q89-", - "T90-", - "R91-", - "L92-", - "G93-", - "S94-", - "S95-", - "H96-", - "T97-", - "Y98-", - "I99-", - "K100-", - "F101-", - "S102-", - "N103-", - "M104-", - "N105-", - "T106-", - "G107-", - "V108-", - "P109-", - "S110-", - "S111-", - "I112-", - "P113-", - "K114-", - "C115-", - "S116-", - "R117-", - "T118-", - "L119-", - "X120-", - "I121-", - "S122-", - "V123-", - "Y124-", - "C125-", - "D126-", - "Q127-", - "E128-", - "A129-", - "G130-", - "D131-", - "I132-", - "K133-", - "F134-", - "E135-", - "E136-", - "Y137-", - "T138-", - "Q139-", - "E140-", - "S141-", - "S142-", - "D143-", - "I144-", - "S145-", - "I146-", - "R147-", - "V148-", - "K149-", - "Y150-", - "D151-", - "S152-", - "S153-", - "C154-", - "I155-", - "D156-", - "Y157-", - "L158-", - "G159-", - "I160-", - "N161-", - "Q162-", - "S163-", - "F164-", - "M165-", - "N166-", - "E167-", - "C168-", - "I169-", - "R170-", - "R171-", - "I172-", - "T173-", - "T174-", - "W175-", - "D176-", - "R177-", - "E178-", - "S179-", - "C180-", - "V181-", - "R182-", - "I183-", - "D184-", - "T185-", - "Q186-", - "T187-", - "I188-", - "N189-", - "K190-", - "Y191-", - "L192-", - "K193-", - "S194-", - "C195-", - "T196-", - "N197-", - "T198-", - "K199-", - "F200-", - "D201-", - "R202-", - "N203-", - "V204-", - "Y205-", - "K206-", - "R207-", - "Y208X" - ], - "OPG197": [ - "X33V" - ], - "OPG204": [ - "H336Y" - ], - "OPG210": [ - "L733I" - ] - }, - "labels": { - "aa": "OPG003: D437Y; OPG019: A11T; OPG023: N135K, R555L, K637E; OPG025: N601K; OPG037: V89M; OPG039: V277D; OPG040: X37D, X376*; OPG052: K64E; OPG074: T599N; OPG083: T97M; OPG085: V587M; OPG099: F37L; OPG100: K152Q; OPG105: V846I; OPG109: D294E; OPG145: M439T; OPG153: A292T; OPG155: T65I; OPG160: M1I; OPG161: A65T; OPG172: S70A; OPG181: A232T; OPG188: N356K, Q376R; OPG195: I39N, R47X, T48-, D49-, C50-, S51-, V52-, H53-, R54-, P55-, T56-, A57-, S58-, G59-, G60-, L61-, I62-, T63-, E64-, G65-, N66-, G67-, F68-, R69-, V70-, X71-, X72-, Y73-, D74-, Q75-, C76-, T77-, E78-, P79-, H80-, D81-, F82-, I83-, I84-, T85-, D86-, T87-, Q88-, Q89-, T90-, R91-, L92-, G93-, S94-, S95-, H96-, T97-, Y98-, I99-, K100-, F101-, S102-, N103-, M104-, N105-, T106-, G107-, V108-, P109-, S110-, S111-, I112-, P113-, K114-, C115-, S116-, R117-, T118-, L119-, X120-, I121-, S122-, V123-, Y124-, C125-, D126-, Q127-, E128-, A129-, G130-, D131-, I132-, K133-, F134-, E135-, E136-, Y137-, T138-, Q139-, E140-, S141-, S142-, D143-, I144-, S145-, I146-, R147-, V148-, K149-, Y150-, D151-, S152-, S153-, C154-, I155-, D156-, Y157-, L158-, G159-, I160-, N161-, Q162-, S163-, F164-, M165-, N166-, E167-, C168-, I169-, R170-, R171-, I172-, T173-, T174-, W175-, D176-, R177-, E178-, S179-, C180-, V181-, R182-, I183-, D184-, T185-, Q186-, T187-, I188-, N189-, K190-, Y191-, L192-, K193-, S194-, C195-, T196-, N197-, T198-, K199-, F200-, D201-, R202-, N203-, V204-, Y205-, K206-, R207-, Y208X; OPG197: X33V; OPG204: H336Y; OPG210: L733I" - } - }, - "children": [ - { - "name": "MPXV-USA2003_099_Gambian_Rat", - "node_attrs": { - "div": 472, - "author": { - "author": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y.", - "value": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "date": { - "value": "2003-XX-XX" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "MPXV-USA2003_099_Gambian_Rat" - }, - "strain": { - "value": "MT903346" - }, - "host": { - "value": "Cricetomys gambianus" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000044", - "node_attrs": { - "div": 473, - "clade_membership": { - "value": "IIa" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-600T", - "C137626T", - "-196608A" - ] - } - }, - "children": [ - { - "name": "DQ011157", - "node_attrs": { - "div": 473, - "author": { - "author": "Likos,A.M., Sammons,S.A., Olson,V.A., Frace,A.M., Li,Y., Olsen-Rasmussen,M., Davidson,W., Galloway,R., Khristova,M.L., Reynolds,M.G., Zhao,H., Carroll,D.S., Curns,A., Formenty,P., Esposito,J.J., Regnery,R.L., Damon,I.K., Olsen-Rasmussen,M.S.", - "value": "Likos,A.M., Sammons,S.A., Olson,V.A., Frace,A.M., Li,Y., Olsen-Rasmussen,M., Davidson,W., Galloway,R., Khristova,M.L., Reynolds,M.G., Zhao,H., Carroll,D.S., Curns,A., Formenty,P., Esposito,J.J., Regnery,R.L., Damon,I.K., Olsen-Rasmussen,M.S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Center for Infectious Diseases, Centers for Disease Control and Prevention (US CDC), USA" - }, - "date": { - "value": "2003-XX-XX" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "DQ011157" - }, - "strain": { - "value": "DQ011157" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV-USA2003_099_Rope_Squirrel", - "node_attrs": { - "div": 473, - "author": { - "author": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y.", - "value": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "date": { - "value": "2003-XX-XX" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "MPXV-USA2003_099_Rope_Squirrel" - }, - "strain": { - "value": "MT903348" - }, - "host": { - "value": "Funisciurus" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "DQ011153", - "node_attrs": { - "div": 473, - "author": { - "author": "Likos,A.M., Sammons,S.A., Olson,V.A., Frace,A.M., Li,Y., Olsen-Rasmussen,M., Davidson,W., Galloway,R., Khristova,M.L., Reynolds,M.G., Zhao,H., Carroll,D.S., Curns,A., Formenty,P., Esposito,J.J., Regnery,R.L., Damon,I.K., Olsen-Rasmussen,M.S.", - "value": "Likos,A.M., Sammons,S.A., Olson,V.A., Frace,A.M., Li,Y., Olsen-Rasmussen,M., Davidson,W., Galloway,R., Khristova,M.L., Reynolds,M.G., Zhao,H., Carroll,D.S., Curns,A., Formenty,P., Esposito,J.J., Regnery,R.L., Damon,I.K., Olsen-Rasmussen,M.S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Center for Infectious Diseases, Centers for Disease Control and Prevention (US CDC), USA" - }, - "date": { - "value": "2003-XX-XX" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "DQ011153" - }, - "strain": { - "value": "DQ011153" - }, - "host": { - "value": "Cynomys" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C49T" - ] - } - } - }, - { - "name": "MPXV-USA2003_099_Dormouse", - "node_attrs": { - "div": 473, - "author": { - "author": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y.", - "value": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "date": { - "value": "2003-XX-XX" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "MPXV-USA2003_099_Dormouse" - }, - "strain": { - "value": "MT903347" - }, - "host": { - "value": "Gliridae" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000047", - "node_attrs": { - "div": 406, - "clade_membership": { - "value": "IIa" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G707A", - "C2959T", - "G3843A", - "C5441A", - "-7068A", - "A7069G", - "G7186A", - "C13709T", - "T19165A", - "T28278C", - "T38382A", - "G47813T", - "G85661A", - "A85968G", - "A88560T", - "T97911C", - "C115877T", - "T136553-", - "C136554-", - "C136555-", - "A136556-", - "T136557-", - "C136558-", - "A136559-", - "T136560-", - "T136570-", - "A161535-", - "-168588C", - "T170897-", - "G174525-", - "A174526-", - "T174527-", - "G174528-", - "A174529-", - "A174530-", - "G191769T", - "C193367T", - "G194251A", - "C196503T" - ], - "NBT03_gp175": [ - "W239L" - ], - "OPG003": [ - "S550N" - ], - "OPG015": [ - "W239L" - ], - "OPG025": [ - "C520Y" - ], - "OPG044": [ - "V63A" - ], - "OPG056": [ - "D218V" - ], - "OPG107": [ - "K153E" - ], - "OPG134": [ - "A43V" - ], - "OPG153": [ - "E366X", - "M370-", - "M371-", - "D372X", - "*510X" - ], - "OPG195": [ - "X120S" - ] - }, - "labels": { - "aa": "NBT03_gp175: W239L; OPG003: S550N; OPG015: W239L; OPG025: C520Y; OPG044: V63A; OPG056: D218V; OPG107: K153E; OPG134: A43V; OPG153: E366X, M370-, M371-, D372X, *510X; OPG195: X120S" - } - }, - "children": [ - { - "name": "NODE_0000048", - "node_attrs": { - "div": 432, - "clade_membership": { - "value": "IIa" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A2760-", - "A2761-", - "G3051A", - "-4693C", - "-4694T", - "-4695T", - "C5809T", - "T13272-", - "A13273-", - "T15508-", - "T15509-", - "T15510-", - "A15511-", - "A15512-", - "C15513-", - "G15514-", - "T15515-", - "C15516-", - "A15517-", - "A15518-", - "T15519-", - "G15520-", - "G15521-", - "T15522-", - "A15523-", - "C15524-", - "A15525-", - "A15526-", - "A15527-", - "T15528-", - "C19281T", - "G19891A", - "T20697C", - "T24732C", - "-25368A", - "G36310T", - "T38583C", - "T48389G", - "T62580A", - "C71655G", - "C79980T", - "T80764G", - "C87501T", - "C93701T", - "A95738G", - "C125798T", - "-133090T", - "G133112-", - "C145219A", - "T146874-", - "A146875-", - "T146876-", - "A146877-", - "T146878-", - "T146879-", - "T146880-", - "A156894C", - "A164460T", - "C164835T", - "-169763A", - "-169764C", - "-169765A", - "-169767A", - "A169772G", - "-172087T", - "G178332T", - "-179072A", - "-179076T", - "T180075A", - "T180218C", - "A183473G", - "G191401A", - "-192515A", - "-192516A", - "-192517G", - "C194159T", - "T194449-", - "T194450-" - ], - "OPG034": [ - "R39C" - ], - "OPG036": [ - "D123G" - ], - "OPG040": [ - "X37D", - "X376*" - ], - "OPG056": [ - "N151S" - ], - "OPG091": [ - "L96V" - ], - "OPG102": [ - "T299I" - ], - "OPG104": [ - "N86H" - ], - "OPG147": [ - "V64M" - ], - "OPG197": [ - "-32T", - "X33D", - "N35D" - ], - "OPG208": [ - "N270K", - "F318S" - ] - }, - "labels": { - "aa": "OPG034: R39C; OPG036: D123G; OPG040: X37D, X376*; OPG056: N151S; OPG091: L96V; OPG102: T299I; OPG104: N86H; OPG147: V64M; OPG197: -32T, X33D, N35D; OPG208: N270K, F318S" - } - }, - "children": [ - { - "name": "KJ642616", - "node_attrs": { - "div": 451, - "author": { - "author": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Lil,Y., Weil,R.M., Muyembe,J.-J., Kingbeni,P.M., Balilo,M.", - "value": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Lil,Y., Weil,R.M., Muyembe,J.-J., Kingbeni,P.M., Balilo,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA" - }, - "date": { - "value": "1968-XX-XX" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "KJ642616" - }, - "strain": { - "value": "KJ642616" - }, - "country": { - "value": "France" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T580G", - "T19608C", - "T23228A", - "T24498A", - "G27605A", - "C29763T", - "C37493T", - "T56538G", - "A87055G", - "C102787T", - "C112599A", - "G119877A", - "G121660T", - "C125897T", - "G133059A", - "G133454A", - "-136553T", - "-136554C", - "-136570A", - "-146855T", - "-146856A", - "-146857T", - "-146858T", - "-146859T", - "-146860T", - "-146861A", - "T146881-", - "A146882-", - "T146883-", - "T146884-", - "T146885-", - "T146886-", - "A146887-", - "T150587-", - "A150588-", - "T150589-", - "G150590-", - "A150591-", - "G150593-", - "G150594-", - "A150595-", - "T150601A", - "C156438A", - "A157609C", - "C158379T", - "A160363-", - "G160364-", - "G163255A", - "G168753T", - "A196630C" - ], - "OPG034": [ - "Y133C" - ], - "OPG040": [ - "Q327H" - ], - "OPG047": [ - "D478N" - ], - "OPG074": [ - "K196N" - ], - "OPG108": [ - "V2A" - ], - "OPG147": [ - "A31T" - ], - "OPG153": [ - "X366D", - "X372D", - "X510*" - ], - "OPG195": [ - "W175L" - ] - }, - "labels": { - "aa": "OPG034: Y133C; OPG040: Q327H; OPG047: D478N; OPG074: K196N; OPG108: V2A; OPG147: A31T; OPG153: X366D, X372D, X510*; OPG195: W175L" - } - } - }, - { - "name": "NODE_0000049", - "node_attrs": { - "div": 435, - "clade_membership": { - "value": "IIa" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C7611A", - "C65892T", - "G116640A", - "C133520-", - "T136541-", - "C136542-", - "A136543-", - "T136544-", - "C136545-", - "A136546-", - "T136547-", - "C136548-", - "A136549-", - "T136550-", - "C136551-", - "A136552-", - "A136561-", - "T136562-", - "C136563-", - "A136564-", - "T136565-", - "C136566-", - "A136567-", - "T136568-", - "C136569-", - "G148316-", - "-150592A", - "-196603A" - ], - "OPG019": [ - "A11D" - ], - "OPG084": [ - "P391S" - ], - "OPG135": [ - "S91L" - ], - "OPG153": [ - "D367-", - "D368-", - "D369-", - "X372-", - "D373-", - "D374-", - "D375-", - "D376X" - ] - }, - "labels": { - "aa": "OPG019: A11D; OPG084: P391S; OPG135: S91L; OPG153: D367-, D368-, D369-, X372-, D373-, D374-, D375-, D376X" - } - }, - "children": [ - { - "name": "AY603973", - "node_attrs": { - "div": 438, - "author": { - "author": "Chen,N., Li,G., Liszewski,M.K., Atkinson,J.P., Jahrling,P.B., Feng,Z., Schriewer,J., Buck,C., Wang,C., Lefkowitz,E.J., Esposito,J.J., Harms,T., Damon,I.K., Roper,R.L., Upton,C., Buller,R.M., Buller,R.M.L.", - "value": "Chen,N., Li,G., Liszewski,M.K., Atkinson,J.P., Jahrling,P.B., Feng,Z., Schriewer,J., Buck,C., Wang,C., Lefkowitz,E.J., Esposito,J.J., Harms,T., Damon,I.K., Roper,R.L., Upton,C., Buller,R.M., Buller,R.M.L." - }, - "institution": { - "value": "Biochemistry & Microbiology, University of Victoria, Canada" - }, - "date": { - "value": "1961-XX-XX" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "AY603973" - }, - "strain": { - "value": "AY603973" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G775A", - "G90845A", - "G92261A", - "A124807G", - "-146855T", - "-146856A", - "-146857T", - "-146858T", - "-146859T", - "-146860T", - "-146861A", - "T146862-", - "A146863-", - "T146864-", - "T146865-", - "T146866-", - "T146867-", - "A146868-", - "T146869-", - "A146870-", - "T146871-", - "T146872-", - "T146873-", - "C196435T" - ], - "OPG111": [ - "S194N" - ] - }, - "labels": { - "aa": "OPG111: S194N" - } - } - }, - { - "name": "NODE_0000050", - "node_attrs": { - "div": 440, - "clade_membership": { - "value": "IIa" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A16608G", - "G32868A", - "G50614A", - "C137466T", - "-146874T", - "-146875A", - "-146876T", - "-146877A", - "-146878T", - "-146879T", - "-146880T", - "C170999T", - "A181246-" - ], - "OPG049": [ - "S95L" - ], - "OPG070": [ - "D9N" - ], - "OPG153": [ - "E68K" - ] - }, - "labels": { - "aa": "OPG049: S95L; OPG070: D9N; OPG153: E68K" - } - }, - "children": [ - { - "name": "AY753185", - "node_attrs": { - "div": 440, - "author": { - "author": "Chen,N., Li,G., Liszewski,M.K., Atkinson,J.P., Jahrling,P.B., Feng,Z., Schriewer,J., Buck,C., Wang,C., Lefkowitz,E.J., Esposito,J.J., Harms,T., Damon,I.K., Roper,R.L., Upton,C., Buller,R.M., Buller,R.M.L.", - "value": "Chen,N., Li,G., Liszewski,M.K., Atkinson,J.P., Jahrling,P.B., Feng,Z., Schriewer,J., Buck,C., Wang,C., Lefkowitz,E.J., Esposito,J.J., Harms,T., Damon,I.K., Roper,R.L., Upton,C., Buller,R.M., Buller,R.M.L." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Biochemistry & Microbiology, University of Victoria, Canada" - }, - "date": { - "value": "1958-XX-XX" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "AY753185" - }, - "strain": { - "value": "AY753185" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MT724769", - "node_attrs": { - "div": 443, - "author": { - "author": "Marien,J., Laudisoit,A., Patrono,L.V., Baelo,P., Musaba,P., Mande,C., Gembu,G., Mussaw,M., van Houtte,N., Van de Perre,F., Gryseels,S., Muyembe-Tamfu,J.-J., Bottieau,E., Calvignac-Spencer,S., Leendertz,F., Leirs,H., Verheyen,E.", - "value": "Marien,J., Laudisoit,A., Patrono,L.V., Baelo,P., Musaba,P., Mande,C., Gembu,G., Mussaw,M., van Houtte,N., Van de Perre,F., Gryseels,S., Muyembe-Tamfu,J.-J., Bottieau,E., Calvignac-Spencer,S., Leendertz,F., Leirs,H., Verheyen,E." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Biology, Universiteit Antwerpen, Belgium" - }, - "date": { - "value": "2012-01-01" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "MT724769" - }, - "strain": { - "value": "MT724769" - }, - "host": { - "value": "Malacomys longipes" - }, - "country": { - "value": "Democratic Republic of the Congo" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T580G", - "T595-", - "C24043A", - "G30588T", - "-136541T", - "-136542C", - "-136543A", - "-136544T", - "-136545C", - "-136546A", - "-136547T", - "-136548C", - "-136549A", - "-136550T", - "-136551C", - "-136552A", - "-136553T", - "-136554C", - "-136561A", - "-136562T", - "-136563C", - "-136564A", - "-136565T", - "-136566C", - "-136567A", - "-136568T", - "-136569C", - "-136570A", - "T146862-", - "A146863-", - "T146864-", - "T146865-", - "T146866-", - "T146867-", - "A146868-", - "T150587-", - "A150588-", - "T150589-", - "G150590-", - "A150591-", - "A150592-", - "G150593-", - "G150594-", - "A150595-", - "T150601A", - "C176924T" - ], - "OPG039": [ - "A26S" - ], - "OPG047": [ - "L203M" - ], - "OPG153": [ - "X366D", - "-367D", - "-368D", - "-369D", - "-372D", - "-373D", - "-374D", - "-375D", - "X376D", - "X510*" - ] - }, - "labels": { - "aa": "OPG039: A26S; OPG047: L203M; OPG153: X366D, -367D, -368D, -369D, -372D, -373D, -374D, -375D, X376D, X510*" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000051", - "node_attrs": { - "div": 417, - "clade_membership": { - "value": "IIa" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T4087G", - "A4864G", - "G7927A", - "G10999A", - "T25366-", - "C25367-", - "C28393T", - "C43244T", - "T69852C", - "C133520T", - "G135371A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-150568G", - "-150585G", - "-150586A", - "-150592T", - "T154017C", - "T163190-", - "A163191-", - "A163192-", - "C163193-", - "T163194-", - "A163195-", - "A163196-", - "C163197-", - "-169767T", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179073-", - "A179074-", - "T179075-", - "C190338T", - "T192346C", - "A193123C" - ], - "OPG003": [ - "E174A" - ], - "OPG040": [ - "D38X" - ], - "OPG063": [ - "V149I" - ], - "OPG197": [ - "X33V" - ] - }, - "labels": { - "aa": "OPG003: E174A; OPG040: D38X; OPG063: V149I; OPG197: X33V" - } - }, - "children": [ - { - "name": "Sierra Leone", - "node_attrs": { - "div": 451, - "author": { - "author": "Chen,N., Li,G., Liszewski,M.K., Atkinson,J.P., Jahrling,P.B., Feng,Z., Schriewer,J., Buck,C., Wang,C., Lefkowitz,E.J., Esposito,J.J., Harms,T., Damon,I.K., Roper,R.L., Upton,C., Buller,R.M., Buller,R.M.L.", - "value": "Chen,N., Li,G., Liszewski,M.K., Atkinson,J.P., Jahrling,P.B., Feng,Z., Schriewer,J., Buck,C., Wang,C., Lefkowitz,E.J., Esposito,J.J., Harms,T., Damon,I.K., Roper,R.L., Upton,C., Buller,R.M., Buller,R.M.L." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Biochemistry & Microbiology, University of Victoria, Canada" - }, - "date": { - "value": "1970-XX-XX" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "Sierra Leone" - }, - "strain": { - "value": "AY741551" - }, - "country": { - "value": "Sierra Leone" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "G2387A", - "G3432A", - "A4696-", - "A4697-", - "C4698-", - "T4699-", - "A4700-", - "A4701-", - "C4702-", - "T4703-", - "T4704-", - "A4705-", - "T4706-", - "G4707-", - "A4708-", - "C4709-", - "T4710-", - "T4711-", - "A4712-", - "A4713-", - "C4714-", - "T4715-", - "A4716-", - "A4717-", - "C4718-", - "T4719-", - "T4720-", - "A4721-", - "T4722-", - "G4723-", - "A4724-", - "C4725-", - "T4726-", - "T4727-", - "A4728-", - "A4729-", - "C4730-", - "T4731-", - "A4732-", - "A4733-", - "C4734-", - "T4735-", - "T4736-", - "A4737-", - "T4738-", - "G4739-", - "A4740-", - "C4741-", - "T4742-", - "T4743-", - "A4744-", - "A4745-", - "C4746-", - "T4747-", - "A4748-", - "A4749-", - "C4750-", - "T4751-", - "T4752-", - "A4753-", - "T4754-", - "G4755-", - "A4756-", - "C4757-", - "T4758-", - "T4759-", - "A4760-", - "A4761-", - "C4762-", - "T4763-", - "A4764-", - "A4765-", - "C4766-", - "T4767-", - "T4768-", - "A4769-", - "T4770-", - "G4771-", - "A4772-", - "C4773-", - "T4774-", - "T4775-", - "G5777T", - "-6916A", - "A6918C", - "A6919C", - "C6920A", - "A6922-", - "A6923-", - "C6924G", - "A6925T", - "A6926T", - "C6927T", - "C6928A", - "T6929A", - "T6930A", - "G6932T", - "T6934C", - "C6936T", - "C6940T", - "G6945T", - "A6950C", - "A6951C", - "T6953G", - "C6954A", - "T6955C", - "T6957A", - "T6958A", - "T6959A", - "A6961T", - "C6964A", - "T6965A", - "A6968T", - "C6970G", - "T6977A", - "C18480T", - "A21930G", - "C28278T", - "G28324A", - "C29640T", - "G79597A", - "C79729A", - "G84125A", - "C84980T", - "C89970T", - "G94626A", - "C94743T", - "G95525A", - "C110255T", - "G118298T", - "C123888A", - "G133545A", - "G134297T", - "C134622T", - "G134915A", - "A136552-", - "-136570T", - "A152605T", - "C154167A", - "C154410T", - "A160208-", - "A160209-", - "C161917T", - "T163179-", - "T163180-", - "A163181-", - "T163182-", - "C163183-", - "T163184-", - "C163185-", - "T163186-", - "T163187-", - "T163188-", - "T163189-", - "T163198-", - "A163199-", - "A163200-", - "C163201-", - "T163202-", - "A163203-", - "A163204-", - "C163205-", - "T163206-", - "A163207-", - "A163208-", - "C163209-", - "T163210-", - "A163211-", - "A163212-", - "C163213-", - "T163214-", - "C163215-", - "G165759A", - "G172195A", - "C175461A", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "G180374A", - "A185597G", - "C188478T", - "C188879T", - "A189894G", - "C191433A", - "A192435-", - "A192436-", - "G192437-", - "T192438-", - "C192439-", - "A192440-", - "T192441-", - "A192442-", - "A192443-", - "G192444-", - "T192445-", - "T192446-", - "A192447-", - "G192448-", - "T192449-", - "T192450-", - "A192451-", - "A192452-", - "G192453-", - "T192454-", - "C192455-", - "A192456-", - "T192457-", - "A192458-", - "A192459-", - "G192460-", - "T192461-", - "T192462-", - "A192463-", - "G192464-", - "T192465-", - "T192466-", - "A192467-", - "A192468-", - "G192469-", - "T192470-", - "C192471-", - "A192472-", - "T192473-", - "A192474-", - "A192475-", - "G192476-", - "T192477-", - "T192478-", - "A192479-", - "G192480-", - "T192481-", - "T192482-", - "A192483-", - "A192484-", - "G192485-", - "T192486-", - "C192487-", - "A192488-", - "T192489-", - "A192490-", - "A192491-", - "G192492-", - "T192493-", - "T192494-", - "A192495-", - "G192496-", - "T192497-", - "T192498-", - "A192499-", - "A192500-", - "G192501-", - "T192502-", - "C192503-", - "A192504-", - "T192505-", - "A192506-", - "A192507-", - "G192508-", - "T192509-", - "T192510-", - "A192511-", - "G192512-", - "T192513-", - "T192514-", - "C193778T", - "C194823T", - "-196601A", - "-196602A", - "-196603A" - ], - "NBT03_gp175": [ - "A127E" - ], - "OPG002": [ - "S122L" - ], - "OPG015": [ - "A127E" - ], - "OPG031": [ - "D117N" - ], - "OPG044": [ - "A63V" - ], - "OPG153": [ - "X366E", - "X372-", - "X510*" - ], - "OPG190": [ - "S213N" - ], - "OPG200": [ - "G16R" - ] - }, - "labels": { - "aa": "NBT03_gp175: A127E; OPG002: S122L; OPG015: A127E; OPG031: D117N; OPG044: A63V; OPG153: X366E, X372-, X510*; OPG190: S213N; OPG200: G16R" - } - } - }, - { - "name": "NODE_0000052", - "node_attrs": { - "div": 446, - "clade_membership": { - "value": "IIa" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "T597-", - "T598-", - "T599-", - "T600-", - "T601-", - "T602-", - "G8774A", - "A8794G", - "G9698A", - "C15082T", - "C20362T", - "C33964T", - "C38427T", - "C45637T", - "C50494A", - "C50572T", - "C55215A", - "G72890T", - "A81454C", - "G93357A", - "G121527T", - "G125116A", - "C128093T", - "T132868C", - "G133163-", - "-133173A", - "G133255A", - "G133426-", - "A136561-", - "T136562-", - "C136563-", - "A136564-", - "T136565-", - "C136566-", - "A136567-", - "T136568-", - "C136569-", - "A142508G", - "C150444A", - "-150569A", - "-150570T", - "-150571A", - "-150572T", - "-150573G", - "-150574A", - "-150575T", - "-150576G", - "-150577G", - "-150578A", - "-150579T", - "-150580A", - "-150581T", - "-150582G", - "-150583A", - "-150584T", - "G151505T", - "C154806T", - "T156450A", - "G156637T", - "C160271G", - "A169757-", - "C169758-", - "A169759-", - "G169760-", - "A169761-", - "T169762-", - "C188457T", - "T189549C", - "A189726-", - "T189727-", - "T189728-", - "A196604-", - "A196605-", - "A196606-", - "A196607-", - "A196608-", - "A196609-", - "A196610-" - ], - "OPG021": [ - "V38I" - ], - "OPG035": [ - "G15S" - ], - "OPG052": [ - "R11Q" - ], - "OPG056": [ - "C203Y" - ], - "OPG064": [ - "A88T" - ], - "OPG092": [ - "Q20K" - ], - "OPG105": [ - "E110A" - ], - "OPG113": [ - "A543T" - ], - "OPG140": [ - "H74N" - ], - "OPG153": [ - "D367-", - "D368-", - "D369-" - ], - "OPG163": [ - "I103V" - ], - "OPG181": [ - "A132V" - ], - "OPG197": [ - "T30-", - "D31-" - ] - }, - "labels": { - "aa": "OPG021: V38I; OPG035: G15S; OPG052: R11Q; OPG056: C203Y; OPG064: A88T; OPG092: Q20K; OPG105: E110A; OPG113: A543T; OPG140: H74N; OPG153: D367-, D368-, D369-; OPG163: I103V; OPG181: A132V; OPG197: T30-, D31-" - } - }, - "children": [ - { - "name": "Cote d'Ivoire_1971", - "node_attrs": { - "div": 462, - "author": { - "author": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Yoshinori,N., Muyembe,J.-J., Kingbeni,P.M.", - "value": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Yoshinori,N., Muyembe,J.-J., Kingbeni,P.M." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA" - }, - "date": { - "value": "1971-XX-XX" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "Cote d'Ivoire_1971" - }, - "strain": { - "value": "KP849470" - }, - "country": { - "value": "Côte d'Ivoire" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A9453-", - "C15861-", - "T15862-", - "C15863-", - "T50662-", - "C52231T", - "C65466T", - "T72702C", - "C72750T", - "A86790G", - "G105195A", - "A111561G", - "G116852A", - "A121165C", - "T134625G", - "T136571-", - "C136572-", - "G136573-", - "C141287T", - "G150543-", - "-150551C", - "-150552G", - "C151475A", - "C162897T", - "-163190T", - "-163191A", - "-163192A", - "-163193C", - "-163194T", - "-163195A", - "-163196A", - "-163197C", - "T163407C", - "C167177T", - "A169751-", - "C169752-", - "A169753-", - "G169754-", - "A169755-", - "T169756-", - "A171862C" - ], - "OPG070": [ - "F25X", - "*274X" - ], - "OPG092": [ - "M66I" - ], - "OPG153": [ - "I365X", - "X366-" - ], - "OPG197": [ - "T28-", - "D29-" - ], - "OPG199": [ - "E292A" - ] - }, - "labels": { - "aa": "OPG070: F25X, *274X; OPG092: M66I; OPG153: I365X, X366-; OPG197: T28-, D29-; OPG199: E292A" - } - } - }, - { - "name": "NODE_0000053", - "node_attrs": { - "div": 448, - "clade_membership": { - "value": "IIa" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C7A", - "A14G", - "G19A", - "G21A", - "C23T", - "T38A", - "T51A", - "G54A", - "C60T", - "G66A", - "T68A", - "A79C", - "T88A", - "G8143T", - "A28532-", - "G156023A", - "A197122T", - "T197131G", - "A197142T", - "C197144T", - "G197150A", - "C197156T", - "A197159T", - "A197172T", - "T197182A", - "A197186C", - "T197192A", - "T197196A", - "G197203T" - ], - "OPG044": [ - "M148X", - "*150X" - ] - }, - "labels": { - "aa": "OPG044: M148X, *150X" - } - }, - "children": [ - { - "name": "DQ011156", - "node_attrs": { - "div": 450, - "author": { - "author": "Likos,A.M., Sammons,S.A., Olson,V.A., Frace,A.M., Li,Y., Olsen-Rasmussen,M., Davidson,W., Galloway,R., Khristova,M.L., Reynolds,M.G., Zhao,H., Carroll,D.S., Curns,A., Formenty,P., Esposito,J.J., Regnery,R.L., Damon,I.K., Olsen-Rasmussen,M.S.", - "value": "Likos,A.M., Sammons,S.A., Olson,V.A., Frace,A.M., Li,Y., Olsen-Rasmussen,M., Davidson,W., Galloway,R., Khristova,M.L., Reynolds,M.G., Zhao,H., Carroll,D.S., Curns,A., Formenty,P., Esposito,J.J., Regnery,R.L., Damon,I.K., Olsen-Rasmussen,M.S." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "National Center for Infectious Diseases, Centers for Disease Control and Prevention (US CDC), USA" - }, - "date": { - "value": "1970-XX-XX" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "DQ011156" - }, - "strain": { - "value": "DQ011156" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Liberia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C39509T", - "G42709T", - "-179066A", - "-179067T", - "-179068T", - "-179069T", - "-179070A", - "-179071T", - "-179072A", - "-179073T", - "-179074A", - "-179075T", - "-179076T" - ], - "OPG063": [ - "T327K" - ] - }, - "labels": { - "aa": "OPG063: T327K" - } - } - }, - { - "name": "NODE_0000054", - "node_attrs": { - "div": 461, - "clade_membership": { - "value": "IIa" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-600T", - "-601T", - "-602T", - "A2840C", - "T6588A", - "T6590C", - "T6591G", - "C6593T", - "C6594A", - "A6597T", - "T6599C", - "A6602G", - "G10039A", - "C12561T", - "A15698-", - "G15699-", - "G46380A", - "A69837G", - "C89937A", - "C101011A", - "A116643G", - "G140316A", - "C159500A", - "T172828A", - "G187503T", - "G188419T", - "A190071-", - "T190072-", - "T194370G", - "-196608A", - "-196609A", - "-196610A" - ], - "OPG023": [ - "V114I" - ], - "OPG065": [ - "A35V" - ], - "OPG135": [ - "V90A" - ], - "OPG185": [ - "A195E" - ] - }, - "labels": { - "aa": "OPG023: V114I; OPG065: A35V; OPG135: V90A; OPG185: A195E" - } - }, - "children": [ - { - "name": "KJ136820", - "node_attrs": { - "div": 465, - "author": { - "author": "Radonic,A., Metzger,S., Dabrowski,P.W., Couacy-Hymann,E., Schuenadel,L., Kurth,A., Matz-Rensing,K., Boesch,C., Leendertz,F.H., Nitsche,A.", - "value": "Radonic,A., Metzger,S., Dabrowski,P.W., Couacy-Hymann,E., Schuenadel,L., Kurth,A., Matz-Rensing,K., Boesch,C., Leendertz,F.H., Nitsche,A." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Centre for Biological Security, Robert Koch Institute, Germany" - }, - "date": { - "value": "2012-03-XX" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "KJ136820" - }, - "strain": { - "value": "KJ136820" - }, - "host": { - "value": "Platyrrhini" - }, - "country": { - "value": "Côte d'Ivoire" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C4538T", - "T16298C", - "G35634A", - "A167909C", - "-179066A", - "-179067T", - "-179068T", - "-179069T", - "-179070A", - "-179071T", - "-179072A", - "-179073T", - "-179074A", - "-179075T", - "-179076T", - "G192672A" - ], - "OPG003": [ - "D24N" - ], - "OPG027": [ - "N27S" - ] - }, - "labels": { - "aa": "OPG003: D24N; OPG027: N27S" - } - } - }, - { - "name": "NODE_0000055", - "node_attrs": { - "div": 465, - "clade_membership": { - "value": "IIa" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A4721-", - "T4722-", - "G4723-", - "A4724-", - "C4725-", - "T4726-", - "T4727-", - "A4728-", - "A4729-", - "C4730-", - "T4731-", - "A4732-", - "G4739A", - "C4741-", - "T4742-", - "T4743-", - "G21441A", - "A27251G", - "-28532A", - "-136553T", - "-136555C", - "-136556A", - "-136557T", - "-136558C", - "-136561A", - "-136562T", - "-136563C", - "-136564A", - "-136565T", - "-136566C", - "-136567A", - "-136568T", - "-136569C", - "-136570A", - "-146855T", - "-146856A", - "-146857T", - "-146858T", - "-146859T", - "-146860T", - "-146861A", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G150568-", - "A150569-", - "T150570-", - "A150571-", - "T150572-", - "G150573-", - "A150574-", - "T150575-", - "G150576-", - "G150577-", - "A150578-", - "T150579-", - "A150580-", - "T150581-", - "G150582-", - "A150583-", - "T150584-", - "-169757A", - "-169758C", - "-169759A", - "-169760G", - "-169761A", - "-169762T", - "-169763A", - "-169764C", - "-169765A", - "T169767A", - "A169772G", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "C186017T", - "A192467-", - "A192468-", - "G192469-", - "C192471T", - "T192477-", - "T192478-", - "A192479-", - "G192480-", - "T192481-", - "T192482-", - "A192483-", - "A192484-", - "G192485-", - "T192486-", - "C192487-", - "A192488-" - ], - "OPG044": [ - "X148M", - "X150*" - ], - "OPG153": [ - "X366D", - "-367D", - "-368D", - "-369D", - "-370X", - "-371M" - ], - "OPG197": [ - "-30T", - "-31D", - "-32T", - "V33D", - "N35D" - ] - }, - "labels": { - "aa": "OPG044: X148M, X150*; OPG153: X366D, -367D, -368D, -369D, -370X, -371M; OPG197: -30T, -31D, -32T, V33D, N35D" - } - }, - "children": [ - { - "name": "NODE_0000056", - "node_attrs": { - "div": 471, - "clade_membership": { - "value": "IIa" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-598T", - "-599T", - "A4744-", - "A4745-", - "C4746-", - "T4747-", - "A4748-", - "A4749-", - "C4750-", - "T4751-", - "T4752-", - "A4753-", - "T4754-", - "G4755-", - "A4756-", - "C4757-", - "T4758-", - "T4759-", - "G57148A", - "C137932T", - "T145514-", - "C152375A", - "G155747T", - "G158403A", - "G177534T", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "-196606A", - "-196607A" - ], - "OPG154": [ - "G40E" - ], - "OPG205": [ - "D627Y" - ] - }, - "labels": { - "aa": "OPG154: G40E; OPG205: D627Y" - } - }, - "children": [ - { - "name": "MPXV_TNP_2018_East_Paddy", - "node_attrs": { - "div": 471, - "author": { - "author": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H.", - "value": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany" - }, - "date": { - "value": "2018-05-11" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "MPXV_TNP_2018_East_Paddy" - }, - "strain": { - "value": "MN346702" - }, - "host": { - "value": "Pan troglodytes verus" - }, - "country": { - "value": "Côte d'Ivoire" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV_TNP_2018_East_Placali", - "node_attrs": { - "div": 474, - "author": { - "author": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H.", - "value": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Robert Koch Institute, Project Group Epidemiology of Highly Pathogenic Microorganisms" - }, - "date": { - "value": "2018-05-20" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "MPXV_TNP_2018_East_Placali" - }, - "strain": { - "value": "MN346703" - }, - "host": { - "value": "Pan troglodytes verus" - }, - "country": { - "value": "Côte d'Ivoire" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-136559A", - "-136560T", - "-173498T", - "-173499A", - "T173504G", - "T173506A", - "T173507G" - ], - "OPG153": [ - "X370M" - ] - }, - "labels": { - "aa": "OPG153: X370M" - } - } - } - ] - }, - { - "name": "NODE_0000057", - "node_attrs": { - "div": 470, - "clade_membership": { - "value": "IIa" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T22263-", - "C22264-", - "T22265-", - "A22266-", - "T22267-", - "G22268-", - "A22269-", - "A22270-", - "G22271-", - "A22272-", - "A22273-", - "G22274-", - "T22275-", - "T22276-", - "C22277-", - "T22278-", - "C44980T", - "C131652T", - "-133163A", - "-133164C", - "-133165A", - "-133166A", - "-133167T", - "-133168C", - "-133169T", - "-133170T", - "-133171T", - "-133172C", - "A133173T", - "T133177-", - "C133178-", - "T133179-", - "T133180-", - "T133181-", - "C133182-", - "T133183-", - "C133184-", - "A133185-", - "A133186-", - "C133187-", - "A133188-", - "T133189-", - "T133190-", - "T133191-", - "C133192-", - "A133193-", - "T133194-", - "C133195-", - "C133196-", - "C133197-", - "C133198-", - "A133199-", - "T133200-", - "G133201-", - "C133202-", - "T133204A", - "T133749C", - "-136559A", - "-136560T", - "C153524A", - "G156651T" - ], - "OPG037": [ - "E52X", - "E53-", - "L54-", - "L55-", - "H56-", - "R57-" - ], - "OPG064": [ - "D307N" - ], - "OPG151": [ - "T910I" - ], - "OPG153": [ - "X370M" - ], - "OPG180": [ - "T278K" - ] - }, - "labels": { - "aa": "OPG037: E52X, E53-, L54-, L55-, H56-, R57-; OPG064: D307N; OPG151: T910I; OPG153: X370M; OPG180: T278K" - } - }, - "children": [ - { - "name": "MPXV_TNP_2017_North_Bic", - "node_attrs": { - "div": 470, - "author": { - "author": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H.", - "value": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany" - }, - "date": { - "value": "2017-03-13" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "MPXV_TNP_2017_North_Bic" - }, - "strain": { - "value": "MN346690" - }, - "host": { - "value": "Pan troglodytes verus" - }, - "country": { - "value": "Côte d'Ivoire" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179154C", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T" - ] - } - } - }, - { - "name": "MPXV_TNP_2017_North_Mama", - "node_attrs": { - "div": 470, - "author": { - "author": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H.", - "value": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany" - }, - "date": { - "value": "2017-03-05" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "MPXV_TNP_2017_North_Mama" - }, - "strain": { - "value": "MN346692" - }, - "host": { - "value": "Pan troglodytes verus" - }, - "country": { - "value": "Côte d'Ivoire" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179120T", - "-179121T", - "-179122A", - "-179123T", - "-179124A", - "-179125T", - "-179126A", - "-179127C", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179154C", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C" - ] - } - } - }, - { - "name": "MPXV_TNP_2017_North_Environmental", - "node_attrs": { - "div": 470, - "author": { - "author": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H.", - "value": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Robert Koch Institute, Project Group Epidemiology of Highly Pathogenic Microorganisms" - }, - "date": { - "value": "2017-03-11" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "MPXV_TNP_2017_North_Environmental" - }, - "strain": { - "value": "MN346691" - }, - "country": { - "value": "Côte d'Ivoire" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T6758A", - "T6759C", - "C6764G", - "T6766A", - "T6767G", - "T6768A", - "G6771C", - "A6772T", - "A6776T", - "C6777G", - "G6778A", - "G6786C", - "A6787T", - "C6792A", - "T6794A", - "A6797T", - "A6799T", - "G6800A", - "G6804A", - "C6805T", - "T6808A", - "C6811G", - "T6814G", - "C6819T", - "A6821T", - "A6823G", - "A6826G", - "T6829A", - "A6833C", - "C6835A", - "A6836C", - "G6837C", - "T6838A", - "C6839A", - "C6841T", - "G6842A", - "T6844C", - "A6845T", - "C6852A", - "G6855A", - "C6858G", - "T6861G", - "A6865C", - "A6866T", - "T6874C", - "C6882T", - "T6884A", - "T6885G", - "T6888C", - "T6890A", - "A6894G", - "G6895A", - "A6896G", - "A6897G", - "A6898C", - "A6899C", - "A6901T", - "A6903G", - "A6911T", - "T6913A", - "-6916T", - "A6918C", - "A6919C", - "C6920A", - "A6922-", - "A6923T", - "C6924T", - "A6925T", - "A6926T", - "C6927A", - "C6928A", - "T6930G", - "G6932T", - "T6933C", - "C6936G", - "C6940A", - "A6941T", - "G6945T", - "T6946A", - "T6947A", - "T6952C", - "T6953A", - "T6955C", - "T6958G", - "C6964A", - "T6965A", - "T6967G", - "T6969C", - "A6971T", - "T6972A", - "G6978T", - "T6979C", - "A6980T", - "A6982T", - "T6983A", - "G6984T", - "G6987A", - "A6989T", - "G6992A", - "A6994T", - "G6995T", - "A7000C", - "A7001T", - "T7003A", - "G7004A", - "T7007G", - "C7014T", - "A7018C", - "A7020C", - "G7021T", - "A7022C", - "C7024T", - "G7026C", - "C7027A", - "A7029T", - "T7033G", - "C7034A", - "G7037C", - "A7041C", - "T7046C", - "A7050C", - "C7053G", - "T7054G", - "A7058T", - "A7059G", - "G7062C", - "T7063G", - "G7065T", - "A7068C", - "G7069A", - "A150540-", - "T150541-", - "A150542-", - "G150543-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "-150562T", - "-150563T", - "-150564T", - "-150565T", - "-150566A", - "-150567T", - "-150568A", - "-150569G", - "-150570T", - "-150571A", - "-150572T", - "-150573G", - "-150574A", - "-150575T", - "-150576G" - ] - } - } - }, - { - "name": "MPXV_TNP_2017_North_Saro", - "node_attrs": { - "div": 470, - "author": { - "author": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H.", - "value": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany" - }, - "date": { - "value": "2017-03-28" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "MPXV_TNP_2017_North_Saro" - }, - "strain": { - "value": "MN346694" - }, - "host": { - "value": "Pan troglodytes verus" - }, - "country": { - "value": "Côte d'Ivoire" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179147T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179154C", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T" - ] - } - } - }, - { - "name": "MPXV_TNP_2017_North_Sidonie", - "node_attrs": { - "div": 470, - "author": { - "author": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H.", - "value": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany" - }, - "date": { - "value": "2017-04-02" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "MPXV_TNP_2017_North_Sidonie" - }, - "strain": { - "value": "MN346695" - }, - "host": { - "value": "Pan troglodytes verus" - }, - "country": { - "value": "Côte d'Ivoire" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV_TNP_2017_North_Surprise_1", - "node_attrs": { - "div": 470, - "author": { - "author": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H.", - "value": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany" - }, - "date": { - "value": "2017-04-03" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "MPXV_TNP_2017_North_Surprise_1" - }, - "strain": { - "value": "MN346696" - }, - "host": { - "value": "Pan troglodytes verus" - }, - "country": { - "value": "Côte d'Ivoire" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179105T", - "-179106A", - "-179107T", - "-179108A", - "-179109C", - "-179110A", - "-179111T", - "-179112T", - "-179113A", - "-179114T", - "-179115A", - "-179116T", - "-179117A", - "-179118C", - "-179119A", - "-179120T", - "-179174T", - "-179176A", - "-179177T", - "-179178A", - "-179179T" - ] - } - } - }, - { - "name": "MPXV_TNP_2017_North_Surprise_2", - "node_attrs": { - "div": 470, - "author": { - "author": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H.", - "value": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Robert Koch Institute, Project Group Epidemiology of Highly Pathogenic Microorganisms" - }, - "date": { - "value": "2017-04-14" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "MPXV_TNP_2017_North_Surprise_2" - }, - "strain": { - "value": "MN346697" - }, - "host": { - "value": "Pan troglodytes verus" - }, - "country": { - "value": "Côte d'Ivoire" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A15918-", - "C15919-", - "T15920-", - "C15921-", - "A15922-", - "T15923-", - "A15924-", - "T15925-", - "T15926-", - "A15927-", - "A15928-", - "T15929-", - "C15930-", - "C15931-", - "A15932-", - "T15933-", - "G15934-", - "G15935-", - "T178963-", - "T178964-", - "G178965-", - "T178966-", - "A178967-", - "T178968-", - "T178969-", - "A178970-", - "T178971-", - "T178972-", - "A178973-", - "A178974-", - "T178975-", - "G178976-", - "G178977-", - "T178978-", - "A178979-", - "T178980-", - "G178981-", - "T178982-", - "A178983-", - "A178984-", - "T178985-", - "A178986-", - "T178987-", - "G178988-", - "A178989-", - "T178990-", - "T178991-" - ], - "OPG027": [ - "S148X", - "M149-", - "D150-", - "*151-" - ] - }, - "labels": { - "aa": "OPG027: S148X, M149-, D150-, *151-" - } - } - }, - { - "name": "MPXV_TNP_2017_South_Pushkin", - "node_attrs": { - "div": 470, - "author": { - "author": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H.", - "value": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany" - }, - "date": { - "value": "2017-01-24" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "MPXV_TNP_2017_South_Pushkin" - }, - "strain": { - "value": "MN346698" - }, - "host": { - "value": "Pan troglodytes verus" - }, - "country": { - "value": "Côte d'Ivoire" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-22263T", - "-22264C", - "-22265T", - "-22266A", - "-22267T", - "-22268G", - "-22269A", - "-22270A", - "-22271G", - "-22272A", - "-22273A", - "-22274G", - "-22275T", - "-22276T", - "-22277C", - "-22278T", - "A136559-", - "T136560-", - "A150540-", - "T150541-", - "A150542-", - "G150543-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "-150581T", - "-150582T", - "-150583A", - "-150584T", - "G150585A", - "A150586G", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-" - ], - "OPG037": [ - "X52E", - "-53E", - "-54L", - "-55L", - "-56H", - "-57R" - ], - "OPG153": [ - "M370X" - ] - }, - "labels": { - "aa": "OPG037: X52E, -53E, -54L, -55L, -56H, -57R; OPG153: M370X" - } - } - }, - { - "name": "MPXV_TNP_2017_South_Ravel_1", - "node_attrs": { - "div": 470, - "author": { - "author": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H.", - "value": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany" - }, - "date": { - "value": "2017-01-23" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "MPXV_TNP_2017_South_Ravel_1" - }, - "strain": { - "value": "MN346699" - }, - "host": { - "value": "Pan troglodytes verus" - }, - "country": { - "value": "Côte d'Ivoire" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-22263T", - "-22264C", - "-22265T", - "-22266A", - "-22267T", - "-22268G", - "-22269A", - "-22270A", - "-22271G", - "-22272A", - "-22273A", - "-22274G", - "-22275T", - "-22276T", - "-22277C", - "-22278T", - "A136559-", - "T136560-", - "A150540-", - "T150541-", - "A150542-", - "G150543-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "-150581T", - "-150582T", - "-150583A", - "-150584T", - "G150585A", - "A150586G", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-" - ], - "OPG037": [ - "X52E", - "-53E", - "-54L", - "-55L", - "-56H", - "-57R" - ], - "OPG153": [ - "M370X" - ] - }, - "labels": { - "aa": "OPG037: X52E, -53E, -54L, -55L, -56H, -57R; OPG153: M370X" - } - } - }, - { - "name": "MPXV_TNP_2017_South_Ravel_2", - "node_attrs": { - "div": 470, - "author": { - "author": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H.", - "value": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany" - }, - "date": { - "value": "2017-01-31" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "MPXV_TNP_2017_South_Ravel_2" - }, - "strain": { - "value": "MN346700" - }, - "host": { - "value": "Pan troglodytes verus" - }, - "country": { - "value": "Côte d'Ivoire" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-22263T", - "-22264C", - "-22265T", - "-22266A", - "-22267T", - "-22268G", - "-22269A", - "-22270A", - "-22271G", - "-22272A", - "-22273A", - "-22274G", - "-22275T", - "-22276T", - "-22277C", - "-22278T", - "A136559-", - "T136560-", - "A150540-", - "T150541-", - "A150542-", - "G150543-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "-150581T", - "-150582T", - "-150583A", - "-150584T", - "G150585A", - "A150586G", - "A179060-", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-" - ], - "OPG037": [ - "X52E", - "-53E", - "-54L", - "-55L", - "-56H", - "-57R" - ], - "OPG153": [ - "M370X" - ] - }, - "labels": { - "aa": "OPG037: X52E, -53E, -54L, -55L, -56H, -57R; OPG153: M370X" - } - } - }, - { - "name": "MPXV_TNP_2017_South_Woodstock", - "node_attrs": { - "div": 470, - "author": { - "author": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H.", - "value": "Patrono,L.V., Pleh,K., Samuni,L., Ulrich,M., Roethemeier,C., Sachse,A., Muschter,S., Nitsche,A., Couacy-Hymann,E., Boesch,C., Wittig,R.M., Calvignac-Spencer,S., Leendertz,F.H." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Robert Koch Institute, Project Group Epidemiology of Highly Pathogenic Microorganisms" - }, - "date": { - "value": "2017-01-14" - }, - "clade_membership": { - "value": "IIa" - }, - "strain_original": { - "value": "MPXV_TNP_2017_South_Woodstock" - }, - "strain": { - "value": "MN346701" - }, - "host": { - "value": "Pan troglodytes verus" - }, - "country": { - "value": "Côte d'Ivoire" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-22263T", - "-22264C", - "-22265T", - "-22266A", - "-22267T", - "-22268G", - "-22269A", - "-22270A", - "-22271G", - "-22272A", - "-22273A", - "-22274G", - "-22275T", - "-22276T", - "-22277C", - "-22278T", - "-136554C", - "C136555-", - "A136556-", - "T136557-", - "C136558-", - "A136559-", - "T136560-", - "A150540-", - "T150541-", - "A150542-", - "G150543-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "-150581T", - "-150582T", - "-150583A", - "-150584T", - "G150585A", - "A150586G", - "A196599-", - "C196600-", - "-196605A", - "-196606A" - ], - "OPG037": [ - "X52E", - "-53E", - "-54L", - "-55L", - "-56H", - "-57R" - ], - "OPG153": [ - "M370-", - "M371-", - "X372D", - "X510*" - ] - }, - "labels": { - "aa": "OPG037: X52E, -53E, -54L, -55L, -56H, -57R; OPG153: M370-, M371-, X372D, X510*" - } - } - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000058", - "node_attrs": { - "div": 473, - "clade_membership": { - "value": "IIb" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C128T", - "G1687A", - "C1813A", - "G1814T", - "G3099T", - "G3420A", - "A4691G", - "T6429C", - "A6430T", - "T6904C", - "T6977C", - "T6983-", - "C7005T", - "G7950T", - "T8286C", - "C8422T", - "C10267A", - "G10275A", - "T10641C", - "C11439T", - "G11593A", - "G11624A", - "G12712A", - "G12733A", - "G16788T", - "T18017A", - "A18861T", - "C19055T", - "T19304A", - "T20990A", - "G22575T", - "C24222T", - "G24358T", - "C24719G", - "G25173T", - "T25212G", - "G25407A", - "T25769G", - "A27215G", - "C28090A", - "T29446C", - "C29655T", - "T30500A", - "A31039G", - "A31793G", - "A32364G", - "C32477A", - "C33043T", - "C33963T", - "T34005C", - "G34295A", - "C34685T", - "A48148C", - "C51168T", - "C55805T", - "C58467T", - "C59256T", - "C67827T", - "G73821A", - "C74303G", - "C74382T", - "C78728A", - "A80756G", - "G81063A", - "T81182C", - "G81463T", - "T82838A", - "G84333A", - "C85163T", - "G86225A", - "G86535A", - "G87049A", - "C87501T", - "G87735A", - "C89214T", - "G89579T", - "G91023A", - "A92009G", - "G92102A", - "T92237C", - "A95477C", - "G95795A", - "G98430T", - "G99212A", - "G99683A", - "C99830T", - "C106115T", - "A107232G", - "T107394C", - "G109382A", - "A109580G", - "C111716T", - "A116660G", - "T120252C", - "G120965A", - "C124737T", - "C124988G", - "G126255A", - "C132719A", - "G133201A", - "C133733T", - "C133966T", - "G134884A", - "G135706A", - "G136498A", - "G136604A", - "G136687A", - "G136870A", - "C143426T", - "C145803A", - "T146862-", - "A146863-", - "T146864-", - "T146865-", - "T146866-", - "T146867-", - "A146868-", - "T146869-", - "A146870-", - "T146871-", - "T146872-", - "T146873-", - "T146874-", - "A146875-", - "T146876-", - "A146877-", - "T146878-", - "T146879-", - "T146880-", - "C147860T", - "A148126G", - "T149765G", - "C150444T", - "-150545A", - "T150756C", - "G154405A", - "C156426T", - "G156512A", - "G156954A", - "C156978T", - "T157273G", - "G157437A", - "C157490T", - "C158175A", - "G158398A", - "G158403A", - "G158511A", - "G158668T", - "G159415A", - "A159447C", - "C160152T", - "C161574T", - "G161799A", - "G162291A", - "C162828T", - "C163467T", - "C164848T", - "C165304T", - "G166399T", - "T167126C", - "C167858T", - "C168277A", - "-168588G", - "G169603A", - "G170248A", - "G170435A", - "-172087T", - "G172188A", - "G172980A", - "G173150A", - "C173441T", - "G173809A", - "C173810T", - "T173882C", - "C174170T", - "A175065C", - "C176160T", - "G177167T", - "C178275T", - "G178395A", - "G178540A", - "A178887G", - "G181350A", - "G181994A", - "G182443A", - "G182491A", - "C183008T", - "G183695A", - "C183696T", - "G184137A", - "T187421C", - "C188096A", - "G189418A", - "G189811T", - "G190098T", - "A190772C", - "T192519C", - "C193790T", - "C194111A", - "C195396A", - "G195397T", - "C195523T" - ], - "NBT03_gp174": [ - "E121D" - ], - "OPG002": [ - "T313N" - ], - "OPG005": [ - "D74N" - ], - "OPG019": [ - "R124M" - ], - "OPG021": [ - "R230K" - ], - "OPG022": [ - "D73G" - ], - "OPG023": [ - "A426V", - "A488T" - ], - "OPG031": [ - "K271M" - ], - "OPG036": [ - "E25D" - ], - "OPG040": [ - "A254P", - "S374Y" - ], - "OPG046": [ - "N95S" - ], - "OPG047": [ - "K232I" - ], - "OPG049": [ - "V37M", - "M263T" - ], - "OPG054": [ - "G438R" - ], - "OPG074": [ - "V441I" - ], - "OPG094": [ - "T175R" - ], - "OPG105": [ - "G113V", - "V1070I" - ], - "OPG108": [ - "A4V" - ], - "OPG118": [ - "R256K", - "S413N", - "A462V" - ], - "OPG125": [ - "V514I" - ], - "OPG130": [ - "A63T" - ], - "OPG145": [ - "T264I", - "P348A" - ], - "OPG153": [ - "T355I" - ], - "OPG164": [ - "H217Y" - ], - "OPG172": [ - "T145M" - ], - "OPG185": [ - "A167T", - "E177D" - ], - "OPG189": [ - "R506C" - ], - "OPG191": [ - "C80F" - ], - "OPG195": [ - "X120C", - "X222*" - ], - "OPG198": [ - "D71N", - "R133Q" - ], - "OPG204": [ - "K178N" - ], - "OPG205": [ - "R169W" - ], - "OPG210": [ - "R363H", - "G379D", - "P781S", - "A928T" - ] - }, - "labels": { - "aa": "NBT03_gp174: E121D; OPG002: T313N; OPG005: D74N; OPG019: R124M; OPG021: R230K; OPG022: D73G; OPG023: A426V, A488T; OPG031: K271M; OPG036: E25D; OPG040: A254P, S374Y; OPG046: N95S; OPG047: K232I; OPG049: V37M, M263T; OPG054: G438R; OPG074: V441I; OPG094: T175R; OPG105: G113V, V1070I; OPG108: A4V; OPG118: R256K, S413N, A462V; OPG125: V514I; OPG130: A63T; OPG145: T264I, P348A; OPG153: T355I; OPG164: H217Y; OPG172: T145M; OPG185: A167T, E177D; OPG189: R506C; OPG191: C80F; OPG195: X120C, X222*; OPG198: D71N, R133Q; OPG204: K178N; OPG205: R169W; OPG210: R363H, G379D, P781S, A928T", - "clade": "clade IIb" - } - }, - "children": [ - { - "name": "KJ642617", - "node_attrs": { - "div": 480, - "author": { - "author": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Lil,Y., Weil,R.M., Muyembe,J.-J., Kingbeni,P.M., Balilo,M.", - "value": "Nakazawa,Y., Mauldin,M.R., Emerson,G.L., Reynolds,M.G., Lash,R.R., Gao,J., Zhao,H., Li,Y., Muyembe,J.J., Kingebeni,P.M., Wemakoy,O., Malekani,J., Karem,K.L., Damon,I.K., Carroll,D.S., Lil,Y., Weil,R.M., Muyembe,J.-J., Kingbeni,P.M., Balilo,M." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA" - }, - "date": { - "value": "1971-XX-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "strain_original": { - "value": "KJ642617" - }, - "strain": { - "value": "KJ642617" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G13625A", - "G98489-", - "C98727T", - "T119718C", - "A129762G", - "G149744A", - "G160174T", - "C160852T", - "G169718-", - "A169719-", - "T169720-", - "C169722-", - "A169723-", - "A169727T", - "A181246-" - ], - "OPG025": [ - "T548M" - ], - "OPG118": [ - "S15X", - "*638X" - ], - "OPG151": [ - "D280G" - ], - "OPG197": [ - "D17-", - "X18-", - "T20S", - "X101*" - ] - }, - "labels": { - "aa": "OPG025: T548M; OPG118: S15X, *638X; OPG151: D280G; OPG197: D17-, X18-, T20S, X101*" - } - } - }, - { - "name": "NODE_0000059", - "node_attrs": { - "div": 500, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G3450A", - "C8893A", - "A16608G", - "G18312A", - "C19367T", - "-32209G", - "-32210A", - "-32211C", - "C33143T", - "G38067A", - "G46895A", - "A48138G", - "C48527A", - "C53207A", - "G66580A", - "C80986T", - "T92516C", - "C100562T", - "T105126C", - "G128076A", - "C133099T", - "C133145T", - "C136555T", - "C136558G", - "G137627A", - "-140105A", - "-140106T", - "-140107A", - "-140108A", - "-140109C", - "-140110A", - "-140111A", - "-140112T", - "-140113T", - "G141300A", - "C141364T", - "C142450A", - "T146687C", - "A149878G", - "-158166A", - "G160867A", - "-166655T", - "-166656T", - "G167656T", - "-169721T", - "G171675A", - "-174519G", - "-174520A", - "-174521T", - "-174522G", - "-174523A", - "-174524A", - "G178423A", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "-187080T", - "C193760T", - "-196603A" - ], - "OPG049": [ - "X314R", - "X315H", - "X319*" - ], - "OPG056": [ - "A323V" - ], - "OPG071": [ - "W411L" - ], - "OPG084": [ - "R620Q" - ], - "OPG104": [ - "A12T" - ], - "OPG150": [ - "D100N" - ], - "OPG153": [ - "T14M", - "M370I", - "M371I" - ], - "OPG159": [ - "X113N", - "-114N", - "-115N", - "X116Y", - "X146*" - ], - "OPG161": [ - "E67K", - "A88V" - ], - "OPG170": [ - "D31G" - ], - "OPG176": [ - "N24D" - ], - "OPG191": [ - "X165Y", - "X166F", - "X169*" - ], - "OPG193": [ - "R108I" - ], - "OPG197": [ - "X18S", - "X101*" - ], - "OPG199": [ - "E230K" - ] - }, - "labels": { - "aa": "OPG049: X314R, X315H, X319*; OPG056: A323V; OPG071: W411L; OPG084: R620Q; OPG104: A12T; OPG150: D100N; OPG153: T14M, M370I, M371I; OPG159: X113N, -114N, -115N, X116Y, X146*; OPG161: E67K, A88V; OPG170: D31G; OPG176: N24D; OPG191: X165Y, X166F, X169*; OPG193: R108I; OPG197: X18S, X101*; OPG199: E230K", - "clade": "A" - } - }, - "children": [ - { - "name": "NODE_0000060", - "node_attrs": { - "div": 503, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "C5157T", - "G7764A", - "G9782A", - "C133161T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "G192053A", - "-196602A" - ], - "NBT03_gp175": [ - "D334N" - ], - "OPG015": [ - "D334N" - ], - "OPG019": [ - "R62K" - ], - "OPG021": [ - "A66T" - ] - }, - "labels": { - "aa": "NBT03_gp175: D334N; OPG015: D334N; OPG019: R62K; OPG021: A66T" - } - }, - "children": [ - { - "name": "MK783028", - "node_attrs": { - "div": 503, - "author": { - "author": "Yinka-Ogunleye,A., Aruna,O., Dalhat,M., Ogoina,D., McCollum,A., Disu,Y., Mamadu,I., Akinpelu,A., Ahmad,A., Burga,J., Ndoreraho,A., Nkunzimana,E., Manneh,L., Mohammed,A., Adeoye,O., Tom-Aba,D., Silenou,B., Ipadeola,O., Saleh,M., Adeyemo,A., Nwadiutor,I., Aworabhi,N., Uke,P., John,D., Wakama,P., Reynolds,M., Mauldin,M., Doty,J., Wilkins,K., Musa,J., Khalakdina,A., Adedeji,A., Mba,N., Ojo,O., Krause,G., Ihekweazu,C., Mauldin,M.R., Li,Y., Gao,J.", - "value": "Yinka-Ogunleye,A., Aruna,O., Dalhat,M., Ogoina,D., McCollum,A., Disu,Y., Mamadu,I., Akinpelu,A., Ahmad,A., Burga,J., Ndoreraho,A., Nkunzimana,E., Manneh,L., Mohammed,A., Adeoye,O., Tom-Aba,D., Silenou,B., Ipadeola,O., Saleh,M., Adeyemo,A., Nwadiutor,I., Aworabhi,N., Uke,P., John,D., Wakama,P., Reynolds,M., Mauldin,M., Doty,J., Wilkins,K., Musa,J., Khalakdina,A., Adedeji,A., Mba,N., Ojo,O., Krause,G., Ihekweazu,C., Mauldin,M.R., Li,Y., Gao,J." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "NCEZID/DHCPP/PRB, Centers for Disease Control & Prevention (US CDC), USA" - }, - "date": { - "value": "2017-11-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MK783028" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "MK783028" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MK783029", - "node_attrs": { - "div": 505, - "author": { - "author": "Yinka-Ogunleye,A., Aruna,O., Dalhat,M., Ogoina,D., McCollum,A., Disu,Y., Mamadu,I., Akinpelu,A., Ahmad,A., Burga,J., Ndoreraho,A., Nkunzimana,E., Manneh,L., Mohammed,A., Adeoye,O., Tom-Aba,D., Silenou,B., Ipadeola,O., Saleh,M., Adeyemo,A., Nwadiutor,I., Aworabhi,N., Uke,P., John,D., Wakama,P., Reynolds,M., Mauldin,M., Doty,J., Wilkins,K., Musa,J., Khalakdina,A., Adedeji,A., Mba,N., Ojo,O., Krause,G., Ihekweazu,C., Mauldin,M.R., Li,Y., Gao,J.", - "value": "Yinka-Ogunleye,A., Aruna,O., Dalhat,M., Ogoina,D., McCollum,A., Disu,Y., Mamadu,I., Akinpelu,A., Ahmad,A., Burga,J., Ndoreraho,A., Nkunzimana,E., Manneh,L., Mohammed,A., Adeoye,O., Tom-Aba,D., Silenou,B., Ipadeola,O., Saleh,M., Adeyemo,A., Nwadiutor,I., Aworabhi,N., Uke,P., John,D., Wakama,P., Reynolds,M., Mauldin,M., Doty,J., Wilkins,K., Musa,J., Khalakdina,A., Adedeji,A., Mba,N., Ojo,O., Krause,G., Ihekweazu,C., Mauldin,M.R., Li,Y., Gao,J." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "NCEZID/DHCPP/PRB, Centers for Disease Control & Prevention (US CDC), USA" - }, - "date": { - "value": "2017-12-06" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MK783029" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "MK783029" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C13797T", - "A20153G" - ], - "OPG025": [ - "D491N" - ] - }, - "labels": { - "aa": "OPG025: D491N" - } - } - }, - { - "name": "MK783031", - "node_attrs": { - "div": 504, - "author": { - "author": "Yinka-Ogunleye,A., Aruna,O., Dalhat,M., Ogoina,D., McCollum,A., Disu,Y., Mamadu,I., Akinpelu,A., Ahmad,A., Burga,J., Ndoreraho,A., Nkunzimana,E., Manneh,L., Mohammed,A., Adeoye,O., Tom-Aba,D., Silenou,B., Ipadeola,O., Saleh,M., Adeyemo,A., Nwadiutor,I., Aworabhi,N., Uke,P., John,D., Wakama,P., Reynolds,M., Mauldin,M., Doty,J., Wilkins,K., Musa,J., Khalakdina,A., Adedeji,A., Mba,N., Ojo,O., Krause,G., Ihekweazu,C., Mauldin,M.R., Li,Y., Gao,J.", - "value": "Yinka-Ogunleye,A., Aruna,O., Dalhat,M., Ogoina,D., McCollum,A., Disu,Y., Mamadu,I., Akinpelu,A., Ahmad,A., Burga,J., Ndoreraho,A., Nkunzimana,E., Manneh,L., Mohammed,A., Adeoye,O., Tom-Aba,D., Silenou,B., Ipadeola,O., Saleh,M., Adeyemo,A., Nwadiutor,I., Aworabhi,N., Uke,P., John,D., Wakama,P., Reynolds,M., Mauldin,M., Doty,J., Wilkins,K., Musa,J., Khalakdina,A., Adedeji,A., Mba,N., Ojo,O., Krause,G., Ihekweazu,C., Mauldin,M.R., Li,Y., Gao,J." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "NCEZID/DHCPP/PRB, Centers for Disease Control & Prevention (US CDC), USA" - }, - "date": { - "value": "2017-11-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MK783031" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "MK783031" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G109736A" - ] - } - } - } - ] - }, - { - "name": "NODE_0000061", - "node_attrs": { - "div": 502, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G18769A", - "G100261A" - ], - "OPG118": [ - "E606K" - ] - }, - "labels": { - "aa": "OPG118: E606K" - } - }, - "children": [ - { - "name": "MPXV_Nigeria_2018_5194", - "node_attrs": { - "div": 522, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "date": { - "value": "2018-01-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MPXV_Nigeria_2018_5194" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP535317" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G50184A", - "C156953A", - "G156961A", - "G156962C", - "G156984A", - "C156990A", - "T156995A", - "T156998A", - "T157010A", - "T157072A", - "G157078A", - "T157091A", - "C157095A", - "G157097A", - "T157098A", - "T157100A", - "T157101A", - "T157103A", - "A157108C", - "A157116C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A" - ], - "OPG069": [ - "E67K" - ] - }, - "labels": { - "aa": "OPG069: E67K" - } - } - }, - { - "name": "NODE_0000062", - "node_attrs": { - "div": 504, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "G81977A", - "-146862T", - "-146863A", - "-146864T", - "-146865T", - "-146866T", - "-146867T", - "-146868A", - "-146869T", - "-146870A", - "-146871T", - "-146872T", - "-146873T", - "-146874T", - "-146875A", - "-146876T", - "-146877A", - "-146878T", - "-146879T", - "-146880T", - "C154408T", - "-196601A", - "-196602A" - ] - } - }, - "children": [ - { - "name": "MPXV-M5312_HM12_Rivers", - "node_attrs": { - "div": 505, - "author": { - "author": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Senkevich,T.G., Yutin,N., Wolf,Y.I., Koonin,E.V., Moss,B., Zmasek,C.M., Knipe,D.M., Pellett,P.E., Scheuermann,R.H.", - "value": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Senkevich,T.G., Yutin,N., Wolf,Y.I., Koonin,E.V., Moss,B., Zmasek,C.M., Knipe,D.M., Pellett,P.E., Scheuermann,R.H." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "National Center for Biotechnology Information, NIH" - }, - "date": { - "value": "2018-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MPXV-M5312_HM12_Rivers" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "NC_063383" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C28175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A" - ] - } - } - }, - { - "name": "MPXV_Nigeria_2018_5232", - "node_attrs": { - "div": 504, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "date": { - "value": "2018-01-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MPXV_Nigeria_2018_5232" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP535332" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "C179217-", - "C179226-" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000063", - "node_attrs": { - "div": 503, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G51559A", - "C60923T", - "C179217-", - "C179226-", - "G179884A" - ], - "OPG080": [ - "E366K" - ], - "OPG208": [ - "E207K" - ] - }, - "labels": { - "aa": "OPG080: E366K; OPG208: E207K" - } - }, - "children": [ - { - "name": "MPXV-M2940_FCT", - "node_attrs": { - "div": 505, - "author": { - "author": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y.", - "value": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "date": { - "value": "2018-XX-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MPXV-M2940_FCT" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "MT903337" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G169718-", - "A169719-", - "T169720-", - "T169721-", - "C169722-", - "A169723-", - "A169727T", - "G172784A", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "T181577C" - ], - "OPG197": [ - "D17-", - "S18-", - "T20S" - ] - }, - "labels": { - "aa": "OPG197: D17-, S18-, T20S" - } - } - }, - { - "name": "MPXV_Nigeria_2017_5227", - "node_attrs": { - "div": 507, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "date": { - "value": "2017-12-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MPXV_Nigeria_2017_5227" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP535318" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "C23311T", - "G75512A", - "G124715A", - "-146862T", - "-146863A", - "-146864T", - "-146865T", - "-146866T", - "-146867T", - "-146868A", - "-146869T", - "-146870A", - "-146871T", - "-146872T", - "-146873T", - "-146874T", - "-146875A", - "-146876T", - "-146877A", - "-146878T", - "-146879T", - "-146880T", - "G162165A", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "-196602A" - ], - "OPG039": [ - "E270K" - ], - "OPG095": [ - "R237K" - ], - "OPG145": [ - "D257N" - ] - }, - "labels": { - "aa": "OPG039: E270K; OPG095: R237K; OPG145: D257N" - } - } - }, - { - "name": "MPXV_Nigeria_2018_5315", - "node_attrs": { - "div": 509, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "date": { - "value": "2018-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MPXV_Nigeria_2018_5315" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP535326" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C23000T", - "G29826A", - "C109667T", - "A136513-", - "T136514-", - "C136515-", - "-146862T", - "-146863A", - "-146864T", - "-146865T", - "-146866T", - "-146867T", - "-146868A", - "-146869T", - "-146870A", - "-146871T", - "-146872T", - "-146873T", - "-146874T", - "-146875A", - "-146876T", - "-146877A", - "-146878T", - "-146879T", - "-146880T", - "G147459A", - "G155644A", - "G177009A" - ], - "OPG038": [ - "G54S" - ], - "OPG047": [ - "R457C" - ], - "OPG153": [ - "D385-" - ], - "OPG205": [ - "E452K" - ] - }, - "labels": { - "aa": "OPG038: G54S; OPG047: R457C; OPG153: D385-; OPG205: E452K" - } - } - }, - { - "name": "NODE_0000064", - "node_attrs": { - "div": 507, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T595-", - "C101683T", - "C127245T", - "G178814A", - "G178988A", - "A196603-" - ], - "OPG149": [ - "S17L" - ] - }, - "labels": { - "aa": "OPG149: S17L" - } - }, - "children": [ - { - "name": "MPXV_Nigeria_2018_5222", - "node_attrs": { - "div": 507, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "date": { - "value": "2018-02-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MPXV_Nigeria_2018_5222" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP535312" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G169718-", - "A169719-", - "T169720-", - "T169721-", - "C169722-", - "A169723-", - "A169727T", - "G174522-", - "A174523-", - "A174524-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG197": [ - "D17-", - "S18-", - "T20S" - ] - }, - "labels": { - "aa": "OPG197: D17-, S18-, T20S" - } - } - }, - { - "name": "MPXV_Nigeria_2018_5223", - "node_attrs": { - "div": 507, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "date": { - "value": "2018-02-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MPXV_Nigeria_2018_5223" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP535334" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-146862T", - "-146863A", - "-146864T", - "-146865T", - "-146866T", - "-146867T", - "-146868A", - "-146869T", - "-146870A", - "-146871T", - "-146872T", - "-146873T", - "-146874T", - "-146875A", - "-146876T", - "-146877A", - "-146878T", - "-146879T", - "-146880T", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000065", - "node_attrs": { - "div": 502, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T595-", - "G37209A", - "G48180A", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "C179217-", - "C179226-", - "A196603-" - ], - "OPG056": [ - "S609F" - ] - }, - "labels": { - "aa": "OPG056: S609F" - } - }, - "children": [ - { - "name": "NODE_0000066", - "node_attrs": { - "div": 504, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G3477A", - "C98046T", - "C193733T" - ] - } - }, - "children": [ - { - "name": "MPXV_Nigeria_2017_2979", - "node_attrs": { - "div": 510, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "date": { - "value": "2017-10-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MPXV_Nigeria_2017_2979" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP535321" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C16092T", - "C120237T", - "C127906T", - "G161496A", - "C170217T", - "G174056A", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-" - ], - "OPG027": [ - "E96K" - ], - "OPG150": [ - "S43L" - ], - "OPG187": [ - "R292Q" - ] - }, - "labels": { - "aa": "OPG027: E96K; OPG150: S43L; OPG187: R292Q" - } - } - }, - { - "name": "MPXV_Nigeria_2017_2945", - "node_attrs": { - "div": 508, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "date": { - "value": "2017-10-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MPXV_Nigeria_2017_2945" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP535337" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C767T", - "G21991A", - "C51364T", - "G52483A", - "G169718-", - "A169719-", - "T169720-", - "T169721-", - "C169722-", - "A169723-", - "A169727T", - "C172965T", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "G196443A" - ], - "OPG037": [ - "S148L" - ], - "OPG197": [ - "D17-", - "S18-", - "T20S" - ] - }, - "labels": { - "aa": "OPG037: S148L; OPG197: D17-, S18-, T20S" - } - } - } - ] - }, - { - "name": "NODE_0000067", - "node_attrs": { - "div": 506, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C8385T", - "G43118A", - "C113841T", - "A136513-", - "T136514-", - "C136515-", - "C146607T", - "-146862T", - "-146863A", - "-146864T", - "-146865T", - "-146866T", - "-146867T", - "-146868A", - "-146869T", - "-146870A", - "-146871T", - "-146872T", - "-146873T", - "-146874T", - "-146875A", - "-146876T", - "-146877A", - "-146878T", - "-146879T", - "-146880T" - ], - "OPG133": [ - "G619E" - ], - "OPG153": [ - "D385-" - ], - "OPG170": [ - "E58K" - ] - }, - "labels": { - "aa": "OPG133: G619E; OPG153: D385-; OPG170: E58K" - } - }, - "children": [ - { - "name": "MPXV_Nigeria_2018_5316", - "node_attrs": { - "div": 506, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "date": { - "value": "2018-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MPXV_Nigeria_2018_5316" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP535325" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T6690G", - "A6712C", - "A6745T", - "-136513A", - "-136514T", - "-136515C", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-" - ], - "OPG153": [ - "-385D" - ] - }, - "labels": { - "aa": "OPG153: -385D" - } - } - }, - { - "name": "MPXV_Nigeria_2018_5306", - "node_attrs": { - "div": 506, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "date": { - "value": "2018-03-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MPXV_Nigeria_2018_5306" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP535328" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G169718-", - "A169719-", - "T169720-", - "T169721-", - "C169722-", - "A169723-", - "G169724-", - "A169725-", - "T169726-", - "A169727-", - "C169728-", - "A169729-", - "-196603A" - ], - "OPG197": [ - "D17-", - "S18-", - "D19-", - "T20-" - ] - }, - "labels": { - "aa": "OPG197: D17-, S18-, D19-, T20-" - } - } - }, - { - "name": "MPXV_Nigeria_2018_5305", - "node_attrs": { - "div": 506, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M., Howard,D., Sheth,M., Seabolt,M.H., Li,Y." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "date": { - "value": "2018-03-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MPXV_Nigeria_2018_5305" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP535329" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "A196604-" - ] - } - } - }, - { - "name": "NODE_0000068", - "node_attrs": { - "div": 507, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G29889A", - "T76079-", - "A89100-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "A173300-", - "T173301-", - "A173302-", - "T173303-", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG047": [ - "P436S" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG109": [ - "F116X", - "*796X" - ] - }, - "labels": { - "aa": "OPG047: P436S; OPG097: K266X, *345X; OPG109: F116X, *796X" - } - }, - "children": [ - { - "name": "NODE_0000069", - "node_attrs": { - "div": 510, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C40251T", - "C63801T", - "T121116-", - "G162243A", - "-196602A", - "-196603A" - ], - "OPG058": [ - "D62N" - ], - "OPG083": [ - "E306K" - ], - "OPG138": [ - "N6X", - "*191X" - ] - }, - "labels": { - "aa": "OPG058: D62N; OPG083: E306K; OPG138: N6X, *191X" - } - }, - "children": [ - { - "name": "MPXV/021/19", - "node_attrs": { - "div": 512, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "date": { - "value": "2019-04-03" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MPXV/021/19" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP612680" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C63264T", - "-89100A", - "T104748C", - "T133095-", - "T133096-", - "T133097-", - "T133098-", - "T133099-", - "T187080-" - ], - "OPG109": [ - "X116F", - "X796*" - ], - "OPG123": [ - "D108G" - ] - }, - "labels": { - "aa": "OPG109: X116F, X796*; OPG123: D108G" - } - } - }, - { - "name": "MPXV/046/19", - "node_attrs": { - "div": 513, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "date": { - "value": "2019-05-13" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MPXV/046/19" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP612684" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C92830T", - "A136516-", - "T136517-", - "C136518-", - "A136519-", - "T136520-", - "C136521-", - "A136522-", - "T136523-", - "C136524-", - "-173302A", - "-173303T", - "G180656A", - "G186423A", - "-196601A" - ], - "OPG113": [ - "S367F" - ], - "OPG153": [ - "D382-", - "D383-", - "D384-" - ], - "OPG209": [ - "D47N" - ], - "OPG210": [ - "E1690K" - ] - }, - "labels": { - "aa": "OPG113: S367F; OPG153: D382-, D383-, D384-; OPG209: D47N; OPG210: E1690K" - } - } - } - ] - }, - { - "name": "NODE_0000070", - "node_attrs": { - "div": 510, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C28164T", - "C87027T", - "G121454A" - ], - "OPG044": [ - "S25F" - ] - }, - "labels": { - "aa": "OPG044: S25F" - } - }, - "children": [ - { - "name": "MPXV/017/19", - "node_attrs": { - "div": 513, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "date": { - "value": "2019-03-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MPXV/017/19" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP612678" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G46685A", - "G144659A", - "G165688A", - "T187080-", - "A196604-" - ], - "OPG167": [ - "S250F" - ] - }, - "labels": { - "aa": "OPG167: S250F" - } - } - }, - { - "name": "NODE_0000071", - "node_attrs": { - "div": 512, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G3531A", - "T151621G", - "T179068A" - ], - "OPG178": [ - "F38C" - ] - }, - "labels": { - "aa": "OPG178: F38C" - } - }, - "children": [ - { - "name": "MPXV/007/19", - "node_attrs": { - "div": 513, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "date": { - "value": "2019-02-03" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MPXV/007/19" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP612675" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T4676C", - "-89100A", - "C193679T" - ], - "OPG109": [ - "X116F", - "X796*" - ] - }, - "labels": { - "aa": "OPG109: X116F, X796*" - } - } - }, - { - "name": "MPXV/013/19", - "node_attrs": { - "div": 514, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "date": { - "value": "2019-02-26" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MPXV/013/19" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP612676" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A1687G", - "G1689T", - "A19353-", - "A22434-", - "T133097-", - "T133098-", - "T133099-", - "A138468-", - "A156764-", - "G162952-", - "T172831-", - "C172832-", - "A172833-", - "A172834-", - "A172835-", - "T172836-", - "A172837-", - "A172838-", - "A172839-", - "T172840-", - "A172841-", - "C172842-", - "G172843-", - "C172844-", - "T172845-", - "A172846-", - "T172847-", - "C172848-", - "A172849-", - "T172850-", - "C172851-", - "C172852-", - "G172853-", - "G172854-", - "A172855-", - "T172856-", - "A172857-", - "T172858-", - "A172859-", - "A172860-", - "T179072A", - "C179226T" - ], - "OPG155": [ - "F8X", - "*147X" - ], - "OPG188": [ - "G453X", - "*504X" - ] - }, - "labels": { - "aa": "OPG155: F8X, *147X; OPG188: G453X, *504X" - } - } - } - ] - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000072", - "node_attrs": { - "div": 501, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G154015A" - ], - "OPG180": [ - "D442N" - ] - }, - "labels": { - "aa": "OPG180: D442N" - } - }, - "children": [ - { - "name": "MK783032", - "node_attrs": { - "div": 509, - "author": { - "author": "Yinka-Ogunleye,A., Aruna,O., Dalhat,M., Ogoina,D., McCollum,A., Disu,Y., Mamadu,I., Akinpelu,A., Ahmad,A., Burga,J., Ndoreraho,A., Nkunzimana,E., Manneh,L., Mohammed,A., Adeoye,O., Tom-Aba,D., Silenou,B., Ipadeola,O., Saleh,M., Adeyemo,A., Nwadiutor,I., Aworabhi,N., Uke,P., John,D., Wakama,P., Reynolds,M., Mauldin,M., Doty,J., Wilkins,K., Musa,J., Khalakdina,A., Adedeji,A., Mba,N., Ojo,O., Krause,G., Ihekweazu,C., Mauldin,M.R., Li,Y., Gao,J.", - "value": "Yinka-Ogunleye,A., Aruna,O., Dalhat,M., Ogoina,D., McCollum,A., Disu,Y., Mamadu,I., Akinpelu,A., Ahmad,A., Burga,J., Ndoreraho,A., Nkunzimana,E., Manneh,L., Mohammed,A., Adeoye,O., Tom-Aba,D., Silenou,B., Ipadeola,O., Saleh,M., Adeyemo,A., Nwadiutor,I., Aworabhi,N., Uke,P., John,D., Wakama,P., Reynolds,M., Mauldin,M., Doty,J., Wilkins,K., Musa,J., Khalakdina,A., Adedeji,A., Mba,N., Ojo,O., Krause,G., Ihekweazu,C., Mauldin,M.R., Li,Y., Gao,J." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "NCEZID/DHCPP/PRB, Centers for Disease Control & Prevention (US CDC), USA" - }, - "date": { - "value": "2017-11-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "strain_original": { - "value": "MK783032" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "MK783032" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "C10430T", - "C18699T", - "G26002A", - "C134814T", - "C143669T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "G180039A", - "G180827A", - "G189317A", - "-196602A" - ], - "OPG005": [ - "R40K" - ], - "OPG031": [ - "D44N" - ], - "OPG042": [ - "R366C" - ], - "OPG165": [ - "L52F" - ], - "OPG208": [ - "M258I" - ], - "OPG209": [ - "E104K" - ] - }, - "labels": { - "aa": "OPG005: R40K; OPG031: D44N; OPG042: R366C; OPG165: L52F; OPG208: M258I; OPG209: E104K" - } - } - }, - { - "name": "NODE_0000073", - "node_attrs": { - "div": 516, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T595-", - "C13298T", - "C18792T", - "C30636T", - "C34472T", - "C34578T", - "G80099A", - "G93387A", - "G114659A", - "G124031A", - "A136513-", - "T136514-", - "C136515-", - "A136516-", - "T136517-", - "C136518-", - "A136519-", - "T136520-", - "C136521-", - "-146862T", - "-146863A", - "-146864T", - "-146865T", - "-146866T", - "-146867T", - "-146868A", - "-146869T", - "-146870A", - "-146871T", - "-146872T", - "-146873T", - "-146874T", - "-146875A", - "-146876T", - "-146877A", - "-146878T", - "-146879T", - "-146880T", - "C148529-", - "A148530-", - "T148531-", - "A148532-", - "T148533-", - "C148534-", - "A148535-", - "G149265A", - "C149872T", - "C161953T", - "C165782T", - "G168205A", - "C177720T" - ], - "OPG031": [ - "D13N" - ], - "OPG047": [ - "D187N" - ], - "OPG053": [ - "G38E" - ], - "OPG113": [ - "E553K" - ], - "OPG145": [ - "D29N" - ], - "OPG153": [ - "D383-", - "D384-", - "D385-" - ], - "OPG174": [ - "S44L", - "N287X", - "D288-", - "M289-", - "*347X" - ], - "OPG176": [ - "Q22*" - ], - "OPG188": [ - "H120Y" - ], - "OPG190": [ - "P221S" - ], - "OPG205": [ - "R689C" - ] - }, - "labels": { - "aa": "OPG031: D13N; OPG047: D187N; OPG053: G38E; OPG113: E553K; OPG145: D29N; OPG153: D383-, D384-, D385-; OPG174: S44L, N287X, D288-, M289-, *347X; OPG176: Q22*; OPG188: H120Y; OPG190: P221S; OPG205: R689C", - "clade": "A.2" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_VA001", - "node_attrs": { - "div": 538, - "author": { - "author": "Gigante,C.M., Griffin-Thomas,L.A., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Crain,J., Li,Y.", - "value": "Gigante,C.M., Griffin-Thomas,L.A., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Crain,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2" - }, - "strain_original": { - "value": "MPXV_USA_2022_VA001" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON675438" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G11332A", - "G12099A", - "C13648T", - "C15105T", - "C16227T", - "C29887T", - "C42101T", - "G64216A", - "G75614A", - "C117119T", - "C128534T", - "G130454A", - "C134442T", - "C142918T", - "G144446A", - "C156429T", - "C164832T", - "C168532T", - "G174610A", - "A175229-", - "T175230-", - "A175231-", - "T175232-", - "C175233-", - "G175234-", - "T175235-", - "A175236-", - "G175237-", - "T175238-", - "A175239-", - "T175240-", - "C175241-", - "A175242-", - "A175243-", - "G175244-", - "A175245-", - "T175246-", - "G175247-", - "T175248-", - "A175249-", - "A175250-", - "A175251-", - "A175252-", - "T175253-", - "A175254-", - "C175255-", - "T175256-", - "T175257-", - "A175258-", - "C175259-", - "G175260-", - "G175261-", - "T175262-", - "T175263-", - "A175264-", - "T175265-", - "A175266-", - "C175267-", - "C175268-", - "G175269-", - "T175270-", - "C175271-", - "A175272-", - "C175273-", - "A175274-", - "A175275-", - "G175276-", - "A175277-", - "C175278-", - "C175279-", - "A175280-", - "C175281-", - "A175282-", - "G175283-", - "G175284-", - "T175285-", - "T175286-", - "T175287-", - "A175288-", - "A175289-", - "A175290-", - "C175291-", - "T175292-", - "A175293-", - "A175294-", - "T175295-", - "A175296-", - "C175297-", - "T175298-", - "A175299-", - "G175300-", - "A175301-", - "T175302-", - "C175303-", - "C175304-", - "G175305-", - "A175306-", - "A175307-", - "A175308-", - "A175309-", - "T175310-", - "C175311-", - "A175312-", - "A175313-", - "C175314-", - "G175315-", - "T175316-", - "A175317-", - "A175318-", - "C175319-", - "G175320-", - "A175321-", - "T175322-", - "A175323-", - "G175324-", - "G175325-", - "A175326-", - "G175327-", - "A175328-", - "A175329-", - "C175330-", - "C175331-", - "T175332-", - "G175333-", - "C175334-", - "C175335-", - "A175336-", - "A175337-", - "T175338-", - "A175339-", - "T175340-", - "A175341-", - "A175342-", - "C175343-", - "A175344-", - "T175345-", - "G175346-", - "C175347-", - "A175348-", - "G175349-", - "T175350-", - "G175351-", - "C175352-", - "T175353-", - "G175354-", - "T175355-", - "G175356-", - "T175357-", - "C175358-", - "A175359-", - "A175360-", - "C175361-", - "G175362-", - "T175363-", - "C175364-", - "A175365-", - "T175366-", - "T175367-", - "A175368-", - "T175369-", - "T175370-", - "T175371-", - "G175372-", - "T175373-", - "C175374-", - "G175375-", - "A175376-", - "C175377-", - "G175378-", - "A175379-", - "T175380-", - "G175381-", - "T175382-", - "A175383-", - "C175384-", - "T175385-", - "G175386-", - "A175387-", - "T175388-", - "T175389-", - "G175390-", - "A175391-", - "A175392-", - "T175393-", - "G175394-", - "G175395-", - "G175396-", - "A175397-", - "A175398-", - "A175399-", - "A175400-", - "T175401-", - "C175402-", - "C175403-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "C179217-", - "C179226-", - "A179628G", - "C179853T", - "G188544A" - ], - "OPG023": [ - "R268*" - ], - "OPG025": [ - "D55N", - "M540I" - ], - "OPG027": [ - "D51N" - ], - "OPG062": [ - "S52L" - ], - "OPG096": [ - "D10N" - ], - "OPG151": [ - "E511K" - ], - "OPG204": [ - "E27K", - "D233X", - "I234-", - "V235-", - "V236-", - "S237-", - "R238-", - "C239-", - "K240-", - "I241-", - "L242-", - "T243-", - "V244-", - "I245-", - "P246-", - "S247-", - "Q248-", - "D249-", - "H250-", - "R251-", - "F252-", - "K253-", - "L254-", - "I255-", - "L256-", - "D257-", - "P258-", - "K259-", - "I260-", - "N261-", - "V262-", - "T263-", - "I264-", - "G265-", - "E266-", - "P267-", - "A268-", - "N269-", - "I270-", - "T271-", - "C272-", - "S273-", - "A274-", - "V275-", - "S276-", - "T277-", - "S278-", - "L279-", - "F280-", - "V281-", - "D282-", - "D283-", - "V284-", - "L285-", - "I286-", - "E287-", - "W288-", - "E289-", - "N290-", - "P291X", - "*352X" - ] - }, - "labels": { - "aa": "OPG023: R268*; OPG025: D55N, M540I; OPG027: D51N; OPG062: S52L; OPG096: D10N; OPG151: E511K; OPG204: E27K, D233X, I234-, V235-, V236-, S237-, R238-, C239-, K240-, I241-, L242-, T243-, V244-, I245-, P246-, S247-, Q248-, D249-, H250-, R251-, F252-, K253-, L254-, I255-, L256-, D257-, P258-, K259-, I260-, N261-, V262-, T263-, I264-, G265-, E266-, P267-, A268-, N269-, I270-, T271-, C272-, S273-, A274-, V275-, S276-, T277-, S278-, L279-, F280-, V281-, D282-, D283-, V284-, L285-, I286-, E287-, W288-, E289-, N290-, P291X, *352X" - } - } - }, - { - "name": "MPXV/111/19", - "node_attrs": { - "div": 517, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "date": { - "value": "2019-12-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2" - }, - "strain_original": { - "value": "MPXV/111/19" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP612689" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "T133099-", - "G144876A", - "A173201-", - "A173202-", - "C173203-", - "G173204-", - "G173205-", - "A173206-", - "C173207-", - "A173208-", - "C173209-", - "C173210-", - "T173211-", - "G173212-", - "G173213-", - "A173214-", - "A173215-", - "T173216-", - "T173217-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A" - ], - "OPG167": [ - "P178S" - ] - }, - "labels": { - "aa": "OPG167: P178S" - } - } - }, - { - "name": "MPXV/113/19", - "node_attrs": { - "div": 516, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "date": { - "value": "2019-12-20" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2" - }, - "strain_original": { - "value": "MPXV/113/19" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP612690" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "A173300-", - "T173301-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-196602A" - ] - } - } - }, - { - "name": "NODE_0000074", - "node_attrs": { - "div": 531, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G2752A", - "G39173A", - "C57284T", - "G61844A", - "C74226T", - "G118739A", - "C146223T", - "G148427A", - "G150800A", - "G168365A", - "G170317A", - "G172527A", - "C175759T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "C179217-", - "C179226-", - "G189417A", - "C189474T", - "C194458T", - "A196603-" - ], - "OPG075": [ - "R72K" - ], - "OPG170": [ - "D186N" - ], - "OPG195": [ - "E46K" - ], - "OPG198": [ - "D94N" - ], - "OPG205": [ - "A35V" - ] - }, - "labels": { - "aa": "OPG075: R72K; OPG170: D186N; OPG195: E46K; OPG198: D94N; OPG205: A35V", - "clade": "A.2.3" - } - }, - "children": [ - { - "name": "MPXV_USA_2021_TX", - "node_attrs": { - "div": 534, - "author": { - "author": "Gigante,C.M., Stringer,J., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Schulte,J., Li,Y.", - "value": "Gigante,C.M., Stringer,J., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Schulte,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "date": { - "value": "2021-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2.3" - }, - "strain_original": { - "value": "MPXV_USA_2021_TX" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON676707" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C100640T", - "G142636A", - "C186104T" - ] - } - } - }, - { - "name": "Monkeypox/PT0428/2022", - "node_attrs": { - "div": 544, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-01" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2.3" - }, - "strain_original": { - "value": "Monkeypox/PT0428/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555515" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C30669T", - "C45028T", - "G49377A", - "G95355A", - "C121320T", - "G136132A", - "-136519A", - "-136520T", - "-136521C", - "G142265A", - "C159143T", - "C162264T", - "C170573T", - "C180686T", - "C181216T", - "G188229A", - "A196604-" - ], - "OPG047": [ - "E176K" - ], - "OPG064": [ - "E291K" - ], - "OPG068": [ - "D393N" - ], - "OPG139": [ - "A17T" - ], - "OPG153": [ - "-383D" - ], - "OPG163": [ - "D22N" - ], - "OPG185": [ - "S76F" - ], - "OPG198": [ - "S179L" - ], - "OPG209": [ - "Q57*" - ] - }, - "labels": { - "aa": "OPG047: E176K; OPG064: E291K; OPG068: D393N; OPG139: A17T; OPG153: -383D; OPG163: D22N; OPG185: S76F; OPG198: S179L; OPG209: Q57*" - } - } - } - ] - }, - { - "name": "NODE_0000075", - "node_attrs": { - "div": 536, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2.2" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G11948A", - "C14790T", - "G21991A", - "G23118A", - "G38923A", - "G39515A", - "G56546A", - "G57786A", - "G93312A", - "C103019T", - "C112470T", - "C124129T", - "C127906T", - "G135303A", - "A136522-", - "T136523-", - "C136524-", - "G145902A", - "C149365T", - "G155611A", - "G158424A", - "G162640A", - "C179217-", - "C179226-", - "G186984A", - "A196603-", - "A196604-" - ], - "OPG023": [ - "S318F" - ], - "OPG025": [ - "D160N" - ], - "OPG037": [ - "S148L" - ], - "OPG056": [ - "R38C" - ], - "OPG113": [ - "V528I" - ], - "OPG122": [ - "H198Y" - ], - "OPG132": [ - "M357I" - ], - "OPG150": [ - "S43L" - ], - "OPG153": [ - "D382-" - ], - "OPG174": [ - "G11R" - ], - "OPG188": [ - "G349S" - ], - "OPG210": [ - "D1877N" - ] - }, - "labels": { - "aa": "OPG023: S318F; OPG025: D160N; OPG037: S148L; OPG056: R38C; OPG113: V528I; OPG122: H198Y; OPG132: M357I; OPG150: S43L; OPG153: D382-; OPG174: G11R; OPG188: G349S; OPG210: D1877N", - "clade": "A.2.2" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_PA0016", - "node_attrs": { - "div": 543, - "author": { - "author": "Gigante,C.M., Xia,D., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Plipat,N., Li,Y.", - "value": "Gigante,C.M., Xia,D., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Plipat,N., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2.2" - }, - "strain_original": { - "value": "MPXV_USA_2022_PA0016" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP450997" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G451A", - "G20576A", - "C20581T", - "G67351A", - "G78259A", - "G94479A", - "C133402T", - "C176148T", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "C196759T" - ], - "OPG036": [ - "E162K" - ], - "OPG085": [ - "S394F" - ], - "OPG205": [ - "H165Y" - ] - }, - "labels": { - "aa": "OPG036: E162K; OPG085: S394F; OPG205: H165Y" - } - } - }, - { - "name": "NODE_0000076", - "node_attrs": { - "div": 541, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2.2" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C13686T", - "C21861T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G151112A", - "G174721A", - "C188491T" - ], - "OPG025": [ - "E528K" - ], - "OPG037": [ - "M191I" - ], - "OPG204": [ - "A64T" - ] - }, - "labels": { - "aa": "OPG025: E528K; OPG037: M191I; OPG204: A64T" - } - }, - "children": [ - { - "name": "MPXV_UK_2022_9000166", - "node_attrs": { - "div": 545, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-06-29" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2.2" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000166" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP331336" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C27826T", - "G59282A", - "C65743A", - "G85356A" - ], - "OPG043": [ - "E44K" - ], - "OPG084": [ - "P341H" - ], - "OPG106": [ - "S48F" - ] - }, - "labels": { - "aa": "OPG043: E44K; OPG084: P341H; OPG106: S48F" - } - } - }, - { - "name": "hMPXV/Austria/MUW1607960/2023", - "node_attrs": { - "div": 551, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "date": { - "value": "2023-04-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2.2" - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1607960/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR113690" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Austria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C18102T", - "C52429T", - "C86957T", - "G97318A", - "C121394T", - "G129982A", - "G146714A", - "C148895A", - "G165892A", - "G175471A" - ], - "OPG031": [ - "D243N" - ], - "OPG108": [ - "D35N" - ], - "OPG117": [ - "D424N" - ], - "OPG170": [ - "A22V" - ], - "OPG174": [ - "M167I" - ], - "OPG204": [ - "E314K" - ] - }, - "labels": { - "aa": "OPG031: D243N; OPG108: D35N; OPG117: D424N; OPG170: A22V; OPG174: M167I; OPG204: E314K" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000077", - "node_attrs": { - "div": 517, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C25072T", - "A136522-", - "T136523-", - "C136524-" - ], - "OPG040": [ - "R136Q" - ], - "OPG153": [ - "D382-" - ] - }, - "labels": { - "aa": "OPG040: R136Q; OPG153: D382-" - } - }, - "children": [ - { - "name": "MPXV/191/20", - "node_attrs": { - "div": 519, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "date": { - "value": "2020-01-23" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2" - }, - "strain_original": { - "value": "MPXV/191/20" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP612691" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "C90329T", - "C132520T", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "A196603-", - "A196604-" - ], - "OPG111": [ - "S22L" - ] - }, - "labels": { - "aa": "OPG111: S22L" - } - } - }, - { - "name": "NODE_0000078", - "node_attrs": { - "div": 530, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G36898A", - "G42183A", - "C42903T", - "G50346A", - "C54268T", - "C73616T", - "G79406A", - "G105746A", - "A140492C", - "C142498T", - "C157737T", - "C161152T", - "G169718-", - "A169719-", - "T169720-", - "T169721-", - "C169722-", - "A169723-", - "G169724-", - "A169725-", - "T169726-", - "A169727-", - "C169728-", - "A169729-", - "A169733T", - "G174519-", - "A174520-", - "T174521-", - "G174522-", - "A174523-", - "A174524-", - "C179217-", - "C179226-", - "C179537T" - ], - "OPG062": [ - "M79I" - ], - "OPG063": [ - "M262I" - ], - "OPG069": [ - "D121N" - ], - "OPG102": [ - "D108N" - ], - "OPG160": [ - "S195A" - ], - "OPG197": [ - "D17-", - "S18-", - "D19-", - "T20-", - "T22S" - ], - "OPG208": [ - "S91L" - ] - }, - "labels": { - "aa": "OPG062: M79I; OPG063: M262I; OPG069: D121N; OPG102: D108N; OPG160: S195A; OPG197: D17-, S18-, D19-, T20-, T22S; OPG208: S91L", - "clade": "A.2.1" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_FL001", - "node_attrs": { - "div": 533, - "author": { - "author": "Gigante,C.M., Lee,P., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Mendoza,R., Li,Y.", - "value": "Gigante,C.M., Lee,P., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Mendoza,R., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2.1" - }, - "strain_original": { - "value": "MPXV_USA_2022_FL001" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON674051" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T95936A", - "C112544T", - "G163540A" - ], - "OPG116": [ - "D192E" - ], - "OPG132": [ - "D333N" - ], - "OPG189": [ - "E70K" - ] - }, - "labels": { - "aa": "OPG116: D192E; OPG132: D333N; OPG189: E70K" - } - } - }, - { - "name": "NODE_0000079", - "node_attrs": { - "div": 531, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133098-", - "T133099-", - "C184924T" - ], - "OPG210": [ - "S1190L" - ] - }, - "labels": { - "aa": "OPG210: S1190L" - } - }, - "children": [ - { - "name": "Mpox-HCMC-M157", - "node_attrs": { - "div": 543, - "author": { - "author": "Nguyen,D.T., Le,H.M., Huynh,H.T.T., Tang,T.C., Le,N.H., Nguyen,H.H., Nghiem,N.M., Nguyen,H.T.T., Vo,Q.T., Vu,T.T.K., Nguyen,T.T., Phan,T.V., Nguyen,T.L.N., Le,T.M., Vo,Q.M., Dinh,M.N.H., Nguyen,P.T., Tran,P.T.L., Tran,T.T.T., Pham,T.T.N., Nguyen,T.H., Truong,L.T.T., Nguyen,H.N.T., Tran,T.T., Le,K.T.T., Lam,Y.M., Thwaites,G., Thwaites,L., Nguyen,C.V.V., Nguyen,A.T., Le,T.V.", - "value": "Nguyen,D.T., Le,H.M., Huynh,H.T.T., Tang,T.C., Le,N.H., Nguyen,H.H., Nghiem,N.M., Nguyen,H.T.T., Vo,Q.T., Vu,T.T.K., Nguyen,T.T., Phan,T.V., Nguyen,T.L.N., Le,T.M., Vo,Q.M., Dinh,M.N.H., Nguyen,P.T., Tran,P.T.L., Tran,T.T.T., Pham,T.T.N., Nguyen,T.H., Truong,L.T.T., Nguyen,H.N.T., Tran,T.T., Le,K.T.T., Lam,Y.M., Thwaites,G., Thwaites,L., Nguyen,C.V.V., Nguyen,A.T., Le,T.V." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "EI group, Oxford University Clinica Research Unit" - }, - "date": { - "value": "2022-09-26" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2.1" - }, - "strain_original": { - "value": "Mpox-HCMC-M157" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP936000" - }, - "country": { - "value": "Vietnam" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A271-", - "C272-", - "C32252T", - "G51559A", - "A86823T", - "G103706A", - "T133095-", - "T133096-", - "T133097-", - "C152033T", - "T167015G", - "T167017-", - "C167019A", - "A167020T", - "A167021C", - "C167022T", - "G167029C", - "A187574C" - ], - "OPG192": [ - "I96X", - "Q97I", - "R98C", - "G100A", - "*183X" - ] - }, - "labels": { - "aa": "OPG192: I96X, Q97I, R98C, G100A, *183X" - } - } - }, - { - "name": "NODE_0000080", - "node_attrs": { - "div": 534, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G30868A", - "G43103A", - "G102599A", - "A136525-", - "T136526-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-169718G", - "-169719A", - "-169720T", - "-169721T", - "-169722C", - "-169723A", - "-169724G", - "-169725A", - "-169726T", - "-169727A", - "-169728C", - "-169729A", - "T169733A", - "T196595-", - "T196596-", - "T196597-", - "-196601A", - "-196602A" - ], - "OPG063": [ - "P196S" - ], - "OPG122": [ - "D58N" - ], - "OPG153": [ - "D381X", - "*510X" - ], - "OPG197": [ - "-17D", - "-18S", - "-19D", - "-20T", - "S22T" - ] - }, - "labels": { - "aa": "OPG063: P196S; OPG122: D58N; OPG153: D381X, *510X; OPG197: -17D, -18S, -19D, -20T, S22T" - } - }, - "children": [ - { - "name": "MPXV_UK_2022_9000155", - "node_attrs": { - "div": 535, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-06-03" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2.1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000155" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP331335" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T595-", - "-133098T", - "-133099T", - "-136513A", - "-136514T", - "-136515C", - "-136516A", - "-136517T", - "-136518C", - "-136519A", - "-136520T", - "-136521C", - "-136522A", - "-136523T", - "-136524C", - "-136525A", - "-136526T", - "C164210T", - "-174519G", - "-174520A", - "-174521T", - "-174522G", - "-174523A", - "-174524A", - "-196595T", - "-196596T", - "-196597T" - ], - "OPG153": [ - "X381D", - "-382D", - "-383D", - "-384D", - "-385D", - "X510*" - ], - "OPG189": [ - "S293L" - ] - }, - "labels": { - "aa": "OPG153: X381D, -382D, -383D, -384D, -385D, X510*; OPG189: S293L" - } - } - }, - { - "name": "Slovenia-MPXV-30-2022", - "node_attrs": { - "div": 534, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.2.1" - }, - "strain_original": { - "value": "Slovenia-MPXV-30-2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605572" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C131-", - "-594T", - "C136527-" - ], - "OPG153": [ - "X381-", - "X510*" - ] - }, - "labels": { - "aa": "OPG153: X381-, X510*" - } - } - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000081", - "node_attrs": { - "div": 501, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "C187428T" - ] - } - }, - "children": [ - { - "name": "NODE_0000082", - "node_attrs": { - "div": 509, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G56968A", - "G61844A", - "C84008T", - "G96841A", - "C100971T", - "C134078T", - "C151050T", - "G169718-", - "A169719-", - "T169720-", - "T169721-", - "C169722-", - "A169723-", - "G188889-" - ], - "OPG074": [ - "S53L" - ], - "OPG117": [ - "D265N" - ], - "OPG120": [ - "E260K" - ], - "OPG197": [ - "D17-", - "S18-" - ] - }, - "labels": { - "aa": "OPG074: S53L; OPG117: D265N; OPG120: E260K; OPG197: D17-, S18-", - "clade": "A.3" - } - }, - "children": [ - { - "name": "MPXV_Nig_2017_297957", - "node_attrs": { - "div": 524, - "author": { - "author": "Faye,O., Pratt,C.B., Faye,M., Fall,G., Chitty,J.A., Diagne,M.M., Wiley,M.R., Yinka-Ogunleye,A.F., Aruna,S., Etebu,E.N., Aworabhi,N., Ogoina,D., Numbere,W., Mba,N., Palacios,G., Sall,A.A., Ihekweazu,C., Diagne,M., Palacios,G.F., Sall,A.", - "value": "Faye,O., Pratt,C.B., Faye,M., Fall,G., Chitty,J.A., Diagne,M.M., Wiley,M.R., Yinka-Ogunleye,A.F., Aruna,S., Etebu,E.N., Aworabhi,N., Ogoina,D., Numbere,W., Mba,N., Palacios,G., Sall,A.A., Ihekweazu,C., Diagne,M., Palacios,G.F., Sall,A." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "USAMRIID, Center for Genome Sciences" - }, - "date": { - "value": "2017-XX-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.3" - }, - "strain_original": { - "value": "MPXV_Nig_2017_297957" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "MG693723" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A8143-", - "G8144-", - "C8145-", - "A8146-", - "T8147-", - "A8148-", - "T8149-", - "T8150-", - "A8151-", - "A8152-", - "A8153-", - "G8154-", - "T8155-", - "A8156-", - "A8157-", - "A8158-", - "A8159-", - "T8160-", - "C8161-", - "T8162-", - "A8163-", - "G8164-", - "T8165-", - "T8166-", - "A8167-", - "C8168-", - "C8169-", - "T8170-", - "T8171-", - "G8172-", - "A8173-", - "A8174-", - "A8175-", - "A8176-", - "T8177-", - "G8178-", - "A8179-", - "A8180-", - "T8181-", - "A8182-", - "C8183-", - "A8184-", - "G8185-", - "T8186-", - "G8187-", - "G8188-", - "G8189-", - "T8190-", - "G8191-", - "G8192-", - "T8193-", - "T8194-", - "C8195-", - "C8196-", - "G8197-", - "T8198-", - "A8199-", - "T8200-", - "C8201-", - "A8202-", - "C8203-", - "C8204-", - "A8205-", - "G8206-", - "T8207-", - "A8208-", - "A8209-", - "G8210-", - "A8211-", - "A8212-", - "C8213-", - "A8214-", - "T8215-", - "A8216-", - "A8217-", - "T8218-", - "A8219-", - "G8220-", - "T8221-", - "C8222-", - "G8223-", - "A8224-", - "A8225-", - "T8226-", - "A8227-", - "C8228-", - "A8229-", - "G8230-", - "T8231-", - "A8232-", - "T8233-", - "C8234-", - "C8235-", - "G8236-", - "A8237-", - "T8238-", - "T8239-", - "G8240-", - "A8241-", - "G8242-", - "A8243-", - "T8244-", - "T8245-", - "T8246-", - "T8247-", - "G8248-", - "C8249-", - "A8250-", - "T8251-", - "A8252-", - "C8253-", - "A8254-", - "A8255-", - "T8256-", - "A8257-", - "C8258-", - "T8259-", - "A8260-", - "G8261-", - "T8262-", - "C8263-", - "T8264-", - "A8265-", - "G8266-", - "A8267-", - "A8268-", - "A8269-", - "G8270-", - "A8271-", - "A8272-", - "A8273-", - "T8274-", - "T8275-", - "T8276-", - "G8277-", - "T8278-", - "A8279-", - "A8280-", - "T8281-", - "C8282-", - "A8283-", - "T8284-", - "C8285-", - "C8286-", - "T8287-", - "C8288-", - "T8289-", - "G8290-", - "T8291-", - "G8292-", - "A8293-", - "C8294-", - "A8295-", - "G8296-", - "G8297-", - "A8298-", - "G8299-", - "T8300-", - "C8301-", - "C8302-", - "A8303-", - "T8304-", - "A8305-", - "T8306-", - "A8307-", - "T8308-", - "C8309-", - "T8310-", - "G8311-", - "T8312-", - "A8313-", - "T8314-", - "C8315-", - "A8316-", - "T8317-", - "C8318-", - "G8319-", - "T8320-", - "C8321-", - "T8322-", - "A8323-", - "G8324-", - "T8325-", - "T8326-", - "T8327-", - "T8328-", - "T8329-", - "A8330-", - "T8331-", - "C8332-", - "A8333-", - "G8334-", - "T8335-", - "G8336-", - "T8337-", - "C8338-", - "C8339-", - "T8340-", - "A8341-", - "T8342-", - "G8343-", - "C8344-", - "T8345-", - "A8346-", - "T8347-", - "A8348-", - "T8349-", - "T8350-", - "C8351-", - "C8352-", - "T8353-", - "G8354-", - "T8355-", - "T8356-", - "A8357-", - "T8358-", - "C8359-", - "A8360-", - "T8361-", - "C8362-", - "A8363-", - "T8364-", - "T8365-", - "A8366-", - "G8367-", - "T8368-", - "T8369-", - "A8370-", - "A8371-", - "T8372-", - "G8373-", - "A8374-", - "A8375-", - "A8376-", - "A8377-", - "T8378-", - "A8379-", - "A8380-", - "C8381-", - "T8382-", - "C8383-", - "T8384-", - "C8385-", - "G8386-", - "T8387-", - "G8388-", - "C8389-", - "T8390-", - "T8391-", - "C8392-", - "A8393-", - "G8394-", - "A8395-", - "A8396-", - "A8397-", - "A8398-", - "G8399-", - "T8400-", - "C8401-", - "A8402-", - "A8403-", - "A8404-", - "T8405-", - "A8406-", - "T8407-", - "T8408-", - "G8409-", - "T8410-", - "A8411-", - "T8412-", - "C8413-", - "C8414-", - "A8415-", - "T8416-", - "A8417-", - "C8418-", - "A8419-", - "T8420-", - "A8421-", - "T8422-", - "A8423-", - "T8424-", - "C8425-", - "T8426-", - "C8427-", - "C8428-", - "A8429-", - "A8430-", - "A8431-", - "A8432-", - "C8433-", - "T8434-", - "A8435-", - "T8436-", - "C8437-", - "A8438-", - "C8439-", - "T8440-", - "T8441-", - "A8442-", - "T8443-", - "A8444-", - "C8445-", - "G8446-", - "T8447-", - "T8448-", - "T8449-", - "A8450-", - "T8451-", - "C8452-", - "T8453-", - "T8454-", - "T8455-", - "A8456-", - "A8457-", - "C8458-", - "G8459-", - "A8460-", - "A8461-", - "C8462-", - "A8463-", - "T8464-", - "A8465-", - "T8466-", - "A8467-", - "C8468-", - "C8469-", - "T8470-", - "A8471-", - "G8472-", - "A8473-", - "T8474-", - "G8475-", - "G8476-", - "T8477-", - "T8478-", - "A8479-", - "T8480-", - "T8481-", - "T8482-", - "A8483-", - "C8484-", - "T8485-", - "A8486-", - "A8487-", - "C8488-", - "A8489-", - "G8490-", - "A8491-", - "C8492-", - "A8493-", - "T8494-", - "T8495-", - "T8496-", - "T8497-", - "T8498-", - "T8499-", - "C8500-", - "A8501-", - "A8502-", - "G8503-", - "A8504-", - "T8505-", - "C8506-", - "T8507-", - "A8508-", - "T8509-", - "T8510-", - "G8511-", - "A8512-", - "C8513-", - "A8514-", - "A8515-", - "T8516-", - "A8517-", - "A8518-", - "C8519-", - "T8520-", - "C8521-", - "C8522-", - "T8523-", - "A8524-", - "T8525-", - "A8526-", - "G8527-", - "T8528-", - "T8529-", - "T8530-", - "C8531-", - "C8532-", - "A8533-", - "C8534-", - "A8535-", - "T8536-", - "C8537-", - "A8538-", - "A8539-", - "C8540-", - "C8541-", - "A8542-", - "A8543-", - "G8544-", - "T8545-", - "A8546-", - "A8547-", - "T8548-", - "G8549-", - "A8550-", - "T8551-", - "C8552-", - "A8553-", - "T8554-", - "C8555-", - "T8556-", - "A8557-", - "T8558-", - "T8559-", - "G8560-", - "T8561-", - "T8562-", - "A8563-", - "T8564-", - "A8565-", - "T8566-", - "A8567-", - "A8568-", - "C8569-", - "A8570-", - "A8571-", - "T8572-", - "A8573-", - "A8574-", - "C8575-", - "A8576-", - "T8577-", - "A8578-", - "A8579-", - "C8580-", - "T8581-", - "C8582-", - "T8583-", - "T8584-", - "T8585-", - "T8586-", - "C8587-", - "C8588-", - "A8589-", - "T8590-", - "T8591-", - "T8592-", - "T8593-", - "T8594-", - "A8595-", - "T8596-", - "C8597-", - "A8598-", - "G8599-", - "T8600-", - "A8601-", - "T8602-", - "C8603-", - "T8604-", - "A8605-", - "T8606-", - "A8607-", - "T8608-", - "C8609-", - "A8610-", - "A8611-", - "C8612-", - "G8613-", - "T8614-", - "C8615-", - "G8616-", - "T8617-", - "T8618-", - "G8619-", - "T8620-", - "A8621-", - "G8622-", - "T8623-", - "G8624-", - "A8625-", - "A8626-", - "T8627-", - "A8628-", - "G8629-", - "T8630-", - "A8631-", - "G8632-", - "T8633-", - "C8634-", - "A8635-", - "T8636-", - "T8637-", - "G8638-", - "A8639-", - "T8640-", - "C8641-", - "T8642-", - "A8643-", - "T8644-", - "T8645-", - "A8646-", - "T8647-", - "A8648-", - "T8649-", - "G8650-", - "A8651-", - "A8652-", - "A8653-", - "C8654-", - "G8655-", - "G8656-", - "A8657-", - "T8658-", - "A8659-", - "T8660-", - "G8661-", - "T8662-", - "C8663-", - "T8664-", - "A8665-", - "G8666-", - "T8667-", - "T8668-", - "A8669-", - "A8670-", - "T8671-", - "A8672-", - "T8673-", - "T8674-", - "T8675-", - "T8676-", - "C8677-", - "T8678-", - "T8679-", - "T8680-", - "G8681-", - "A8682-", - "T8683-", - "T8684-", - "T8685-", - "A8686-", - "A8687-", - "A8688-", - "G8689-", - "T8690-", - "C8691-", - "T8692-", - "A8693-", - "T8694-", - "A8695-", - "G8696-", - "T8697-", - "C8698-", - "T8699-", - "T8700-", - "T8701-", - "A8702-", - "C8703-", - "A8704-", - "A8705-", - "A8706-", - "C8707-", - "A8708-", - "T8709-", - "A8710-", - "A8711-", - "T8712-", - "A8713-", - "T8714-", - "C8715-", - "C8716-", - "T8717-", - "T8718-", - "A8719-", - "T8720-", - "C8721-", - "C8722-", - "G8723-", - "A8724-", - "C8725-", - "T8726-", - "T8727-", - "T8728-", - "A8729-", - "T8730-", - "A8731-", - "T8732-", - "T8733-", - "T8734-", - "C8735-", - "C8736-", - "T8737-", - "G8738-", - "T8739-", - "A8740-", - "G8741-", - "G8742-", - "G8743-", - "T8744-", - "G8745-", - "G8746-", - "C8747-", - "A8748-", - "T8749-", - "A8750-", - "A8751-", - "T8752-", - "T8753-", - "T8754-", - "T8755-", - "A8756-", - "T8757-", - "T8758-", - "C8759-", - "T8760-", - "G8761-", - "C8762-", - "C8763-", - "T8764-", - "C8765-", - "C8766-", - "A8767-", - "C8768-", - "A8769-", - "A8770-", - "T8771-", - "C8772-", - "A8773-", - "G8774-", - "T8775-", - "G8776-", - "T8777-", - "T8778-", - "T8779-", - "C8780-", - "C8781-", - "A8782-", - "A8783-", - "A8784-", - "T8785-", - "A8786-", - "T8787-", - "A8788-", - "T8789-", - "T8790-", - "A8791-", - "C8792-", - "T8793-", - "A8794-", - "G8795-", - "A8796-", - "C8797-", - "A8798-", - "A8799-", - "T8800-", - "A8801-", - "T8802-", - "T8803-", - "C8804-", - "C8805-", - "A8806-", - "T8807-", - "A8808-", - "T8809-", - "A8810-", - "G8811-", - "T8812-", - "T8813-", - "A8814-", - "T8815-", - "T8816-", - "A8817-", - "G8818-", - "T8819-", - "T8820-", - "A8821-", - "A8822-", - "G8823-", - "G8824-", - "G8825-", - "A8826-", - "C8827-", - "C8828-", - "C8829-", - "A8830-", - "A8831-", - "T8832-", - "T8833-", - "A8834-", - "G8835-", - "A8836-", - "A8837-", - "C8838-", - "A8839-", - "C8840-", - "G8841-", - "T8842-", - "A8843-", - "C8844-", - "G8845-", - "C8846-", - "G8847-", - "C8848-", - "T8849-", - "T8850-", - "A8851-", - "T8852-", - "T8853-", - "C8854-", - "A8855-", - "T8856-", - "C8857-", - "A8858-", - "T8859-", - "T8860-", - "T8861-", - "G8862-", - "G8863-", - "A8864-", - "T8865-", - "C8866-", - "G8867-", - "T8868-", - "A8869-", - "T8870-", - "T8871-", - "T8872-", - "C8873-", - "A8874-", - "T8875-", - "A8876-", - "A8877-", - "A8878-", - "A8879-", - "G8880-", - "T8881-", - "T8882-", - "A8883-", - "T8884-", - "T8885-", - "A8886-", - "T8887-", - "G8888-", - "T8889-", - "T8890-", - "A8891-", - "T8892-", - "A8893-", - "G8894-", - "A8895-", - "T8896-", - "G8897-", - "T8898-", - "C8899-", - "A8900-", - "A8901-", - "C8902-", - "A8903-", - "C8904-", - "A8905-", - "T8906-", - "T8907-", - "C8908-", - "T8909-", - "A8910-", - "C8911-", - "A8912-", - "T8913-", - "T8914-", - "T8915-", - "T8916-", - "T8917-", - "T8918-", - "T8919-", - "A8920-", - "A8921-", - "T8922-", - "T8923-", - "G8924-", - "T8925-", - "C8926-", - "T8927-", - "A8928-", - "T8929-", - "A8930-", - "T8931-", - "A8932-", - "G8933-", - "T8934-", - "A8935-", - "T8936-", - "T8937-", - "T8938-", - "T8939-", - "T8940-", - "C8941-", - "T8942-", - "G8943-", - "A8944-", - "T8945-", - "A8946-", - "T8947-", - "T8948-", - "T8949-", - "T8950-", - "C8951-", - "T8952-", - "A8953-", - "T8954-", - "A8955-", - "A8956-", - "T8957-", - "A8958-", - "T8959-", - "C8960-", - "A8961-", - "G8962-", - "A8963-", - "A8964-", - "T8965-", - "T8966-", - "G8967-", - "T8968-", - "C8969-", - "T8970-", - "T8971-", - "C8972-", - "C8973-", - "A8974-", - "T8975-", - "A8976-", - "G8977-", - "G8978-", - "A8979-", - "A8980-", - "G8981-", - "T8982-", - "T8983-", - "G8984-", - "T8985-", - "A8986-", - "T8987-", - "A8988-", - "C8989-", - "T8990-", - "A8991-", - "T8992-", - "T8993-", - "C8994-", - "G8995-", - "G8996-", - "A8997-", - "A8998-", - "T8999-", - "C9000-", - "A9001-", - "G9002-", - "T9003-", - "T9004-", - "A9005-", - "C9006-", - "A9007-", - "T9008-", - "G9009-", - "T9010-", - "T9011-", - "T9012-", - "A9013-", - "A9014-", - "A9015-", - "T9016-", - "A9017-", - "A9018-", - "T9019-", - "T9020-", - "C9021-", - "T9022-", - "C9023-", - "T9024-", - "G9025-", - "A9026-", - "T9027-", - "G9028-", - "T9029-", - "C9030-", - "A9031-", - "T9032-", - "T9033-", - "C9034-", - "C9035-", - "T9036-", - "T9037-", - "A9038-", - "T9039-", - "A9040-", - "C9041-", - "A9042-", - "A9043-", - "T9044-", - "C9045-", - "A9046-", - "A9047-", - "A9048-", - "T9049-", - "T9050-", - "C9051-", - "A9052-", - "T9053-", - "T9054-", - "A9055-", - "T9056-", - "T9057-", - "A9058-", - "A9059-", - "A9060-", - "C9061-", - "A9062-", - "G9063-", - "T9064-", - "T9065-", - "T9066-", - "A9067-", - "A9068-", - "T9069-", - "A9070-", - "G9071-", - "T9072-", - "C9073-", - "T9074-", - "G9075-", - "T9076-", - "A9077-", - "G9078-", - "A9079-", - "C9080-", - "C9081-", - "T9082-", - "T9083-", - "T9084-", - "A9085-", - "T9086-", - "C9087-", - "G9088-", - "T9089-", - "C9090-", - "G9091-", - "T9092-", - "A9093-", - "C9094-", - "A9095-", - "T9096-", - "A9097-", - "T9098-", - "C9099-", - "C9100-", - "A9101-", - "T9102-", - "T9103-", - "G9104-", - "T9105-", - "C9106-", - "T9107-", - "T9108-", - "A9109-", - "T9110-", - "T9111-", - "A9112-", - "G9113-", - "T9114-", - "T9115-", - "A9116-", - "C9117-", - "G9118-", - "C9119-", - "T9120-", - "T9121-", - "A9122-", - "T9123-", - "T9124-", - "T9125-", - "T9126-", - "T9127-", - "A9128-", - "T9129-", - "G9130-", - "G9131-", - "G9132-", - "T9133-", - "T9134-", - "T9135-", - "T9136-", - "A9137-", - "C9138-", - "G9139-", - "T9140-", - "T9141-", - "G9142-", - "C9143-", - "T9144-", - "T9145-", - "T9146-", - "A9147-", - "T9148-", - "T9149-", - "A9150-", - "T9151-", - "A9152-", - "T9153-", - "T9154-", - "T9155-", - "T9156-", - "A9157-", - "T9158-", - "A9159-", - "A9160-", - "T9161-", - "A9162-", - "A9163-", - "T9164-", - "G9165-", - "A9166-", - "T9167-", - "T9168-", - "G9169-", - "T9170-", - "T9171-", - "T9172-", - "G9173-", - "A9174-", - "C9175-", - "A9176-", - "A9177-", - "T9178-", - "G9179-", - "T9180-", - "C9181-", - "G9182-", - "T9183-", - "A9184-", - "G9185-", - "T9186-", - "A9187-", - "T9188-", - "A9189-", - "G9190-", - "A9191-", - "T9192-", - "A9193-", - "T9194-", - "A9195-", - "T9196-", - "T9197-", - "A9198-", - "T9199-", - "T9200-", - "A9201-", - "G9202-", - "A9203-", - "G9204-", - "G9205-", - "A9206-", - "G9207-", - "G9208-", - "T9209-", - "A9210-", - "T9211-", - "A9212-", - "A9213-", - "T9214-", - "T9215-", - "A9216-", - "T9217-", - "A9218-", - "A9219-", - "A9220-", - "A9221-", - "A9222-", - "G9223-", - "T9224-", - "T9225-", - "T9226-", - "C9227-", - "T9228-", - "G9229-", - "A9230-", - "G9231-", - "T9232-", - "A9233-", - "C9234-", - "G9235-", - "A9236-", - "T9237-", - "G9238-", - "T9239-", - "T9240-", - "A9241-", - "T9242-", - "A9243-", - "A9244-", - "G9245-", - "A9246-", - "G9247-", - "G9248-", - "A9249-", - "G9250-", - "A9251-", - "G9252-", - "G9253-", - "A9254-", - "C9255-", - "A9256-", - "C9257-", - "A9258-", - "T9259-", - "T9260-", - "A9261-", - "A9262-", - "C9263-", - "A9264-", - "T9265-", - "C53702T", - "-146862T", - "-146863A", - "-146864T", - "-146865T", - "-146866T", - "-146867T", - "-146868A", - "-146869T", - "-146870A", - "-146871T", - "-146872T", - "-146873T", - "-146874T", - "-146875A", - "-146876T", - "-146877A", - "-146878T", - "-146879T", - "-146880T", - "A166846-", - "T166847-", - "A166848-", - "A166849-", - "T166850-", - "A166851-", - "T166852-", - "A166853-", - "G166854-", - "A166855-", - "A166856-", - "A166857-", - "A166858-", - "T166859-", - "T166860-", - "C166861-", - "A166862-", - "T166863-", - "A166864-", - "T166865-", - "A166866-", - "C166867-", - "T166868-", - "G166869-", - "A166870-", - "T166871-", - "G166872-", - "A166873-", - "T166874-", - "A166875-", - "A166876-", - "T166877-", - "A166878-", - "A166879-", - "T166880-", - "G166881-", - "A166882-", - "A166883-", - "T166884-", - "T166885-", - "G166886-", - "G166887-", - "T166888-", - "G166889-", - "T166890-", - "T166891-", - "A166892-", - "A166893-", - "A166894-", - "T166895-", - "T166896-", - "T166897-", - "T166898-", - "A166899-", - "A166900-", - "A166901-", - "G166902-", - "A166903-", - "G166904-", - "T166905-", - "A166906-", - "C166907-", - "A166908-", - "C166909-", - "A166910-", - "A166911-", - "T166912-", - "T166913-", - "T166914-", - "C166915-", - "T166916-", - "A166917-", - "T166918-", - "T166919-", - "A166920-", - "T166921-", - "T166922-", - "A166923-", - "C166924-", - "A166925-", - "G166926-", - "A166927-", - "G166928-", - "T166929-", - "C166930-", - "A166931-", - "T166932-", - "G166933-", - "T166934-", - "G166935-", - "A166936-", - "C166937-", - "G166938-", - "T166939-", - "C166940-", - "G166941-", - "G166942-", - "A166943-", - "T166944-", - "T166945-", - "T166946-", - "G166947-", - "A166948-", - "T166949-", - "T166950-", - "C166951-", - "C166952-", - "A166953-", - "T166954-", - "A166955-", - "G166956-", - "A166957-", - "T166958-", - "A166959-", - "T166960-", - "A166961-", - "G166962-", - "A166963-", - "T166964-", - "G166965-", - "T166966-", - "T166967-", - "A166968-", - "T166969-", - "A166970-", - "A166971-", - "A166972-", - "C166973-", - "G166974-", - "A166975-", - "C166976-", - "T166977-", - "A166978-", - "T166979-", - "C168582A", - "C168584-", - "T168585-", - "C168586-", - "T168587-", - "G168588-", - "T168589-", - "A168590-", - "T168591-", - "T168592-", - "T168593-", - "C168594-", - "T168595-", - "G168596-", - "T168597-", - "A168598-", - "T168599-", - "A168600-", - "T168601-", - "T168602-", - "G168603-", - "T168604-", - "G168605-", - "A168606-", - "T168607-", - "C168608-", - "A168609-", - "G168611C", - "G168614-", - "C168615-", - "G168616-", - "G168617-", - "G168618-", - "A168619-", - "G168620-", - "A168621-", - "C168622-", - "A168623-", - "T168624-", - "A168625-", - "A168626-", - "A168627-", - "A168628-", - "T168629-", - "T168630-", - "T168631-", - "G168632-", - "A168633-", - "G168634-", - "G168635-", - "A168636-", - "G168637-", - "T168638-", - "A168639-", - "T168640-", - "A168641-", - "C168642-", - "T168643-", - "C168644-", - "A168645-", - "A168646-", - "G168647-", - "A168648-", - "A168649-", - "T168650-", - "C168651-", - "A168652-", - "A168653-", - "G168654-", - "T168655-", - "G168656-", - "A168657-", - "T168658-", - "A168659-", - "T168660-", - "C168661-", - "A168662-", - "G168663-", - "T168664-", - "A168665-", - "T168666-", - "T168667-", - "A168674C", - "A168675T", - "T168677-", - "A168678-", - "T168679-", - "G168680-", - "A168681-", - "T168682-", - "T168683-", - "C168684-", - "A168685-", - "T168686-", - "C168687-", - "A168688-", - "T168689-", - "G168690-", - "T168691-", - "A168692-", - "T168693-", - "T168694-", - "G168695-", - "A168696-", - "T168697-", - "T168698-", - "A168699-", - "T168700-", - "C168701-", - "T168702-", - "G168703-", - "G168704-", - "G168705-", - "T168706-", - "A168707-", - "T168708-", - "T168709-", - "A168710-", - "A168711-", - "T168712-", - "C168713-", - "A168714-", - "A168715-", - "A168716-", - "G168717-", - "T168718-", - "T168719-", - "T168720-", - "C168721-", - "A168722-", - "T168723-", - "G168724-", - "A168725-", - "A168726-", - "T168727-", - "T168731C", - "G168732A", - "A168734T", - "C168737G", - "G168741-", - "A168742-", - "A168743-", - "T168744-", - "A168748T", - "C168750G", - "G168755-", - "A168756-", - "T168757-", - "A168758-", - "G168759-", - "A168760-", - "G168761-", - "A168762-", - "A168763-", - "T168764-", - "C168765-", - "A168766-", - "T168767-", - "G168768-", - "C168769-", - "G168770-", - "T168771-", - "C168772-", - "A168773-", - "G168774-", - "A168775-", - "T168777G", - "C169569-", - "A169570-", - "T169571-", - "T169572-", - "T169573-", - "A169574-", - "A169575-", - "T169576-", - "A169577-", - "A169578-", - "G169579-", - "G169580-", - "A169581-", - "C169582-", - "A169583-", - "T169584-", - "T169585-", - "G169586-", - "G169587-", - "A169588-", - "T169589-", - "A169590-", - "T169591-", - "G169592-", - "T169593-", - "G169594-", - "G169595-", - "A169596-", - "A169597-", - "A169598-", - "A169599-", - "G169600-", - "T169601-", - "G169602-", - "A169603-", - "T169604-", - "G169605-", - "T169606-", - "A169607-", - "T169608-", - "G169609-", - "G169610-", - "A169611-", - "A169612-", - "G169613-", - "T169614-", - "T169615-", - "A169616-", - "G169617-", - "T169618-", - "A169619-", - "C169620-", - "A169621-", - "T169622-", - "T169623-", - "A169624-", - "T169625-", - "C169626-", - "A169627-", - "A169628-", - "C169629-", - "T169630-", - "T169631-", - "C169632-", - "T169633-", - "C169634-", - "C169635-", - "T169636-", - "T169637-", - "A169638-", - "T169639-", - "T169640-", - "G169641-", - "A169642-", - "T169643-", - "T169644-", - "G169645-", - "A169646-", - "A169647-", - "A169648-", - "A169649-", - "T169650-", - "G169651-", - "A169652-", - "A169653-", - "A169654-", - "A169655-", - "T169656-", - "A169657-", - "T169658-", - "A169659-", - "A169660-", - "A169661-", - "T169662-", - "A169663-", - "G169664-", - "T169665-", - "T169666-", - "T169667-", - "T169668-", - "T169669-", - "A169670-", - "T169671-", - "G169672-", - "T169673-", - "A169674-", - "T169675-", - "A169676-", - "G169677-", - "C169678-", - "G169679-", - "G169680-", - "T169681-", - "A169682-", - "T169683-", - "C169684-", - "T169685-", - "A169686-", - "C169687-", - "C169688-", - "C169689-", - "T169690-", - "A169691-", - "T169692-", - "A169693-", - "G169694-", - "T169695-", - "T169696-", - "T169697-", - "T169698-", - "A169699-", - "T169700-", - "T169701-", - "G169702-", - "C169703-", - "T169704-", - "T169705-", - "A169706-", - "C169707-", - "T169708-", - "A169709-", - "C169710-", - "T169711-", - "A169712-", - "A169713-", - "C169714-", - "A169715-", - "T169716-", - "G169717-", - "G169724-", - "A169725-", - "T169726-", - "A169727-", - "C169728-", - "A169729-", - "G169730-", - "A169731-", - "T169732-", - "A169733-", - "C169734-", - "A169735-", - "G169736-", - "A169737-", - "T169738-", - "A169739-", - "C169740-", - "A169741-", - "G169742-", - "A169743-", - "T169744-", - "A169745-", - "C169746-", - "A169747-", - "G169748-", - "A169749-", - "T169750-", - "A169751-", - "C169752-", - "A169753-", - "G169754-", - "A169755-", - "T187260-", - "G187261-", - "T187262-", - "T187263-", - "T187264-", - "A187265-", - "G187266-", - "A187267-", - "A187268-", - "T187269-", - "C187270-", - "A187271-", - "T187272-", - "T187273-", - "T187274-", - "A187275-", - "T187276-", - "C187277-", - "A187278-", - "T187279-", - "A187280-", - "A187281-", - "C187282-", - "A187290-", - "A187291-", - "T187292-", - "A187293-", - "A187294-", - "A187295-", - "T187296-", - "T187297-", - "C187298-", - "A187299-", - "T187300-", - "C187301-", - "A187302-", - "A187303-", - "C187304-", - "G187305-", - "A187306-", - "A187307-", - "T187308-", - "A187309-", - "T187310-", - "C187311-", - "G187312-", - "A187313-", - "T187314-", - "A187315-", - "A187316-", - "A187317-", - "G187318-", - "A187319-", - "C187320-", - "C187321-", - "T187322-", - "C187323-", - "T187324-", - "T187325-", - "G187326-", - "T187327-", - "A187328-", - "A187329-", - "T187330-", - "T187331-", - "C187332-", - "G187333-", - "A187334-", - "G187335-", - "T187336-", - "A187337-", - "T187338-", - "A187339-", - "G187340-", - "G187341-", - "A187342-", - "A187343-", - "G187344-", - "T187345-", - "A187346-", - "G187347-", - "T187348-", - "A187349-", - "T187350-", - "T187351-", - "A187352-", - "C187353-", - "C187354-", - "A187355-", - "T187356-", - "A187357-", - "T187358-", - "C187359-", - "A187360-", - "A187361-", - "C187362-", - "T187363-", - "T187364-", - "C187365-", - "C187366-", - "G187367-", - "A187368-", - "G187369-", - "T187370-", - "T187371-", - "A187372-", - "A187373-", - "C187374-", - "A187375-", - "A187376-", - "T187377-", - "T187378-", - "A187379-", - "C187380-", - "T187381-", - "C187382-", - "T187383-", - "A187384-", - "A187385-", - "A187386-", - "A187387-", - "C187388-", - "A187389-", - "T187390-", - "G187391-", - "A187392-", - "G187393-", - "G187394-", - "A187395-", - "T187396-", - "T187397-", - "G187398-", - "T187399-", - "A187400-", - "C187401-", - "T187402-", - "C187403-", - "T187407A", - "C187408G", - "T187414-", - "G187415-", - "G187416-", - "A187417-", - "G187418-", - "A187419-", - "T187420-", - "C187421-", - "A187422-", - "C187423-", - "T187424-", - "A187425-", - "T187426-", - "T187427-", - "T187428-", - "A187429-", - "G187430-", - "T187431-", - "C187432-", - "G187433-", - "T187434-", - "T187435-", - "G187436-", - "A187437-", - "T187438-", - "A187439-", - "A187440-", - "A187441-", - "C187442-", - "T187443-", - "A187444-", - "G187445-", - "T187446-", - "A187447-", - "A187448-", - "C187449-", - "C187450-", - "T187451-", - "C187452-", - "A187453-", - "G187454-", - "G187455-", - "T187456-", - "T187457-", - "T187458-", - "C187459-", - "T187460-", - "T187461-", - "T187462-", - "A187463-", - "C187464-", - "A187465-", - "A187466-", - "A187467-", - "C187468-", - "G187469-", - "A187470-", - "T187471-", - "A187472-", - "A187473-", - "A187474-", - "G187475-", - "T187476-", - "A187477-", - "C187478-", - "A187479-", - "A187480-", - "C187481-", - "A187482-", - "T187483-", - "C187484-", - "A187485-", - "A187486-", - "G187487-", - "A187488-", - "C187489-", - "C187490-", - "T187491-", - "C187492-", - "A187493-", - "C187494-", - "A187495-", - "A187496-", - "C187497-", - "A187498-", - "C187499-", - "A187500-", - "G187501-", - "T187502-", - "G187503-", - "C187504-", - "A187505-", - "A187506-", - "G187507-", - "A187508-", - "T187509-", - "T187510-", - "A187511-", - "A187512-", - "T187513-", - "C187514-", - "A187520-", - "T187521-", - "C187522-", - "A187523-", - "A187524-", - "A187525-", - "T187526-", - "G187527-", - "T187528-", - "A187529-", - "A187530-", - "T187531-", - "T187532-", - "C187533-", - "T187534-", - "G187535-", - "G187536-", - "A187537-", - "G187538-", - "G187539-", - "A187540-", - "G187541-", - "A187542-", - "A187543-", - "T187544-", - "C187545-", - "T187546-", - "A187547-", - "G187548-", - "A187549-", - "C187550-", - "A187551-", - "A187552-", - "C187553-", - "T187554-", - "A187555-", - "A187556-", - "C187557-", - "A187558-", - "C187559-", - "C187560-", - "C187561-", - "A187562-", - "C187563-", - "G187564-", - "G187565-", - "C187566-", - "G187567-", - "A187568-", - "A187569-", - "G187570-", - "T187571-", - "A187572-", - "T187573-", - "A187574-", - "C187575-", - "T187576-", - "T187577-", - "T187578-", - "A187579-", - "T187580-", - "G187581-", - "C187582-", - "C187583-", - "T187584-", - "C187585-", - "A187586-", - "T187587-", - "T187588-", - "C187589-", - "A187590-", - "G187591-", - "A187592-", - "A187593-", - "A187594-", - "C187595-", - "G187596-", - "G187597-", - "T187598-", - "A187599-", - "A187600-", - "C187601-", - "T187602-", - "G187603-", - "T187604-", - "A187605-", - "G187606-", - "T187607-", - "A187608-", - "G187609-", - "G187610-", - "A187611-", - "G187612-", - "A187613-", - "C187614-", - "T187615-", - "G187616-", - "T187617-", - "C187618-", - "T187619-", - "C187620-", - "T187621-", - "C187622-", - "T187623-", - "A187624-", - "A187625-", - "T187626-", - "C187627-", - "T187628-", - "C187629-", - "G187630-", - "A187631-", - "T187632-", - "G187633-", - "T187634-", - "A187635-", - "T187636-", - "A187637-", - "T187638-", - "A187639-", - "T187640-", - "A187641-", - "A187642-", - "T187643-", - "A187644-", - "T187645-", - "A187646-", - "T187647-", - "A187648-", - "C187649-", - "C187650-", - "A187651-", - "A187652-", - "T187653-", - "A187654-", - "C187655-", - "G187656-", - "G187657-", - "A187658-", - "C187659-", - "G187660-", - "C187661-", - "G187662-", - "A187663-", - "T187664-", - "A187665-", - "T187666-", - "A187667-", - "T187668-", - "T187669-", - "C187670-", - "C187671-", - "G187672-", - "A187673-", - "C187674-", - "A187675-", - "T187676-", - "G187677-", - "A187678-", - "A187679-", - "T187680-", - "G187681-", - "G187682-", - "C187683-", - "G187684-", - "T187685-", - "C187686-", - "G187687-", - "C187688-", - "T187689-", - "T187690-", - "A187691-", - "T187692-", - "C187693-", - "A187694-", - "T187695-", - "A187696-", - "T187697-", - "G187698-", - "T187699-", - "T187700-", - "A187701-", - "T187702-", - "A187703-", - "T187704-", - "C187705-", - "C187706-", - "T187707-", - "A187708-", - "A187709-", - "A187710-", - "T187711-", - "G187712-", - "T187713-", - "T187714-", - "G187715-", - "A187716-", - "T187717-", - "C187718-", - "A187719-", - "T187720-", - "A187721-", - "T187722-", - "T187723-", - "C187724-", - "C187725-", - "A187726-", - "C187727-", - "A187728-", - "A187729-", - "A187730-", - "T187731-", - "G187732-", - "A187733-", - "T187734-", - "T187735-", - "G187736-", - "T187737-", - "G187738-", - "A187739-", - "A187740-", - "C187741-", - "G187742-", - "A187743-", - "G187744-", - "A187745-", - "T187746-", - "T187747-", - "A187748-", - "A187749-", - "A187750-", - "T187751-", - "C187752-", - "A187753-", - "T187754-", - "C187755-", - "T187756-", - "A187757-", - "A187758-", - "C187759-", - "A187760-", - "A187761-", - "A187762-", - "T187763-", - "A187764-", - "A187765-", - "T187766-", - "T187767-", - "A187768-", - "G187769-", - "T187770-", - "T187771-", - "T187772-", - "T187773-", - "T187774-", - "T187775-", - "A187776-", - "T187777-", - "G187778-", - "A187779-", - "C187780-", - "A187781-", - "T187782-", - "T187783-", - "A187784-", - "A187785-", - "C187786-", - "A187787-", - "T187788-", - "A187789-", - "T187790-", - "A187791-", - "A187792-", - "T187793-", - "A187794-", - "A187795-", - "A187796-", - "T187797-", - "A187798-", - "A187799-", - "A187800-", - "T187801-", - "T187802-", - "A187803-", - "A187804-", - "T187805-", - "C187806-", - "A187807-", - "T187808-", - "T187809-", - "A187810-", - "T187811-", - "T187812-", - "G187813-", - "A187814-", - "C187815-", - "T187816-", - "T187817-", - "A187818-", - "A187819-", - "C187820-", - "G187821-", - "A187822-", - "T187823-", - "G187824-", - "A187825-", - "C187826-", - "G187827-", - "A187828-", - "A187829-", - "A187830-", - "G187831-", - "T187832-", - "T187833-", - "A187834-", - "T187835-", - "C187836-", - "A187837-", - "T187838-", - "T187839-", - "A187840-", - "T187841-", - "C187842-", - "T187843-", - "T187844-", - "A187845-", - "G187846-", - "G187847-", - "A187848-", - "T187849-", - "T187850-", - "C187851-", - "T187852-", - "T187853-", - "G187854-", - "A187855-", - "T187856-", - "T187857-", - "A187858-", - "T187859-", - "T187860-", - "A187861-", - "A187862-", - "T187863-", - "A187864-", - "C187865-", - "A187866-", - "A187867-", - "A187868-", - "T187869-", - "T187870-", - "C187871-", - "G187872-", - "T187873-", - "A188115-", - "G188116-", - "T188117-", - "T188118-", - "A188119-", - "T188120-", - "C188121-", - "G188122-", - "T188123-", - "C188124-", - "T188125-", - "C188126-", - "C188127-", - "T188128-", - "T188129-", - "A188130-", - "A188131-", - "A188132-", - "G188133-", - "C188134-", - "T188135-", - "T188136-", - "C188137-", - "T188138-", - "G188139-", - "A188140-", - "T188141-", - "G188142-", - "G188143-", - "T188144-", - "A188145-", - "A188146-", - "C188147-", - "T188148-", - "G188149-", - "T188150-", - "G188151-", - "T188152-", - "T188153-", - "A188154-", - "C188155-", - "A188156-", - "T188157-", - "G188158-", - "T188159-", - "G188160-", - "C188161-", - "T188162-", - "C188163-", - "C188164-", - "T188165-", - "A188166-", - "A188167-", - "A188168-", - "A188169-", - "C188170-", - "A188171-", - "A188172-", - "A188173-", - "A188174-", - "T188175-", - "A188176-", - "T188177-", - "G188178-", - "G188179-", - "T188180-", - "C188181-", - "G188182-", - "T188183-", - "G188184-", - "T188185-", - "G188186-", - "T188187-", - "A188188-", - "C188189-", - "G188190-", - "G188191-", - "A188192-", - "A188193-", - "A188194-", - "G188195-", - "A188196-", - "A188197-", - "A188198-", - "G188199-", - "G188200-", - "A188201-", - "G188202-", - "A188203-", - "A188204-", - "A188205-", - "A188206-", - "T188207-", - "G188208-", - "A188209-", - "T188210-", - "A188211-", - "T188212-", - "G188213-", - "G188214-", - "A188215-", - "A188216-", - "T188217-", - "A188218-", - "C188219-", - "C188220-", - "A188221-", - "T188222-", - "T188223-", - "T188224-", - "G188225-", - "T188226-", - "A188227-", - "A188228-", - "G188229-", - "A188230-", - "A188231-", - "A188232-", - "T188233-", - "G188234-", - "T188235-", - "C188236-", - "G188237-", - "G188238-", - "A188239-", - "A188240-", - "G188241-", - "G188242-", - "G188243-", - "T188244-", - "A188245-", - "C188246-", - "T188247-", - "T188248-", - "A188249-", - "T188250-", - "T188251-", - "C188252-", - "A188253-", - "G188254-", - "A188255-", - "T188256-", - "A188257-", - "T188258-", - "T188259-", - "G188260-", - "T188261-", - "A188262-", - "T188263-", - "C188264-", - "T188265-", - "G188266-", - "A188267-", - "C188268-", - "T188269-", - "C188270-", - "T188271-", - "G188272-", - "A188273-", - "T188274-", - "C188275-", - "A188276-", - "A188277-", - "T188278-", - "G188279-", - "T188280-", - "A188281-", - "A188282-", - "A188283-", - "C188284-", - "C188285-", - "T188286-", - "A188287-", - "T188288-", - "G188289-", - "A188290-", - "C188291-", - "A188292-", - "A188293-", - "G188294-", - "A188295-", - "T188296-", - "A188297-", - "A188298-", - "G188299-", - "A188300-", - "C188301-", - "T188302-", - "T188303-", - "A188304-", - "C188305-", - "T188306-", - "C188307-", - "G188308-", - "C188309-", - "A188310-", - "T188311-", - "C188312-", - "T188313-", - "A188314-", - "C188315-", - "T188316-", - "G188317-", - "G188318-", - "A188319-", - "T188320-", - "A188321-", - "G188322-", - "A188323-", - "C188324-", - "A188325-", - "T188326-", - "A188327-", - "A188328-", - "A188329-", - "T188330-", - "A188331-", - "T188332-", - "C188333-", - "C188334-", - "T188335-", - "C188336-", - "C188337-", - "T188338-", - "C188339-", - "G188340-", - "T188341-", - "A188342-", - "A188343-", - "T188344-", - "A188345-", - "A188346-", - "T188347-", - "G188348-", - "A188349-", - "A188350-", - "A188351-", - "T188352-", - "A188353-", - "T188354-", - "A188355-", - "A188356-", - "T188357-", - "A188358-", - "T188359-", - "A188360-", - "C188361-", - "A188362-", - "C188363-", - "T188364-", - "A188365-", - "A188366-", - "T188367-", - "T188368-", - "A188369-", - "T188370-", - "T188371-", - "A188372-", - "A188373-", - "T188374-", - "A188375-", - "T188376-", - "C188377-", - "A188378-", - "A188379-", - "T188380-", - "C188381-", - "G188382-", - "A188383-", - "G188384-", - "T188385-", - "A188386-", - "T188387-", - "T188388-", - "A188389-", - "A188390-", - "C188391-", - "A188392-", - "T188393-", - "A188394-", - "T188395-", - "A188396-", - "A188397-", - "G188398-", - "T188399-", - "T188400-", - "A188401-", - "T188402-", - "T188403-", - "T188404-", - "T188405-", - "T188406-", - "A188407-", - "A188408-", - "A188409-", - "C188410-", - "C188411-", - "C188412-", - "C188413-", - "T188414-", - "T188415-", - "T188416-", - "T188417-", - "G188418-", - "G188419-", - "G188420-", - "T188421-", - "T188422-", - "C188423-", - "C188424-", - "G188425-", - "T188426-", - "C188427-", - "C188428-", - "T188429-", - "A188430-", - "A188431-", - "A188432-", - "C188433-", - "G188434-", - "G188435-", - "C188436-", - "G188437-", - "T188438-", - "T188439-", - "T188440-", - "C188441-", - "G188442-", - "G188443-", - "T188444-", - "C188445-", - "T188446-", - "G188447-", - "T188448-", - "G188449-", - "T188450-", - "C188451-", - "G188452-", - "C188453-", - "C188454-", - "A188455-", - "C188456-", - "C188457-", - "A188458-", - "T188459-", - "G188460-", - "G188461-", - "T188462-", - "C188463-", - "A188464-", - "C188465-", - "A188466-", - "C188467-", - "C188468-", - "G188469-", - "A188470-", - "G188471-", - "C188472-", - "C188473-", - "T188474-", - "C188475-", - "T188476-", - "G188477-", - "C188478-", - "G188479-", - "T188480-", - "G188481-", - "C188482-", - "T188483-", - "C188484-", - "C188485-", - "T188486-", - "C188487-", - "C188488-", - "A188489-", - "T188490-", - "C188491-", - "G188492-", - "A188493-", - "G188494-", - "G188495-", - "A188496-", - "C188497-", - "G188498-", - "A188499-", - "C188500-", - "T188501-", - "T188502-", - "C188503-", - "A188504-", - "A188505-", - "C188506-", - "T188507-", - "A188508-", - "T188509-", - "G188510-", - "A188511-", - "C188512-", - "A188513-", - "G188514-", - "C188515-", - "T188516-", - "C188517-", - "G188518-", - "G188519-", - "T188520-", - "G188521-", - "G188522-", - "C188523-", - "G188524-", - "T188525-", - "C188526-", - "T188527-", - "G188528-", - "C188529-", - "C188530-", - "A188531-", - "G188532-", - "C188533-", - "G188534-", - "T188535-", - "G188536-", - "T188537-", - "A188538-", - "C188539-", - "A188540-", - "T188541-", - "A188542-", - "C188543-", - "G188544-", - "A188545-", - "A188546-", - "T188547-", - "G188548-", - "G188549-", - "C188550-", - "A188551-", - "T188552-", - "T188553-", - "T188554-", - "C188555-", - "T188556-", - "A188557-", - "A188558-", - "G188559-", - "A188560-", - "A188561-", - "A188562-", - "A188563-", - "G188564-", - "T188565-", - "C188566-", - "T188567-", - "A188568-", - "C188569-", - "G188570-", - "G188571-", - "T188572-", - "A188573-", - "T188574-", - "C188575-", - "C188576-", - "T188577-", - "T188578-", - "T188579-", - "C188580-", - "T188581-", - "A188582-", - "C188583-", - "A188584-", - "A188585-", - "T188586-", - "T188587-", - "T188588-", - "C188589-", - "C188590-", - "T188591-", - "T188592-", - "T188593-", - "A188594-", - "A188595-", - "C188596-", - "A188597-", - "A188598-", - "C188599-", - "G188600-", - "G188601-", - "C188602-", - "A188603-", - "A188604-", - "C188605-", - "A188606-", - "G188607-", - "C188608-", - "T188609-", - "G188610-", - "C188611-", - "A188612-", - "G188613-", - "T188614-", - "A188615-", - "T188616-", - "T188617-", - "T188618-", - "T188619-", - "T188620-", - "A188621-", - "T188622-", - "A188623-", - "C188624-", - "T188625-", - "T188626-", - "T188627-", - "G188628-", - "A188629-", - "A188630-", - "T188631-", - "G188632-", - "C188633-", - "A188634-", - "T188635-", - "C188636-", - "G188637-", - "G188638-", - "A188639-", - "C188640-", - "A188641-", - "T188642-", - "T188643-", - "T188644-", - "A188645-", - "T188646-", - "A188647-", - "C188648-", - "A188649-", - "A188650-", - "G188651-", - "G188652-", - "G188653-", - "A188654-", - "G188655-", - "T188656-", - "C188657-", - "C188658-", - "T188659-", - "G188660-", - "T188661-", - "T188662-", - "C188663-", - "T188664-", - "A188665-", - "A188666-", - "T188667-", - "A188668-", - "T188669-", - "T188670-", - "G188671-", - "G188672-", - "C188673-", - "A188674-", - "T188675-", - "C188676-", - "A188677-", - "A188678-", - "T188679-", - "G188680-", - "T188681-", - "T188682-", - "C188683-", - "G188684-", - "G188685-", - "A188686-", - "T188687-", - "C188688-", - "T188689-", - "A188690-", - "T188691-", - "A188692-", - "G188693-", - "G188694-", - "C188695-", - "T188696-", - "T188697-", - "G188698-", - "A188699-", - "T188700-", - "T188701-", - "T188702-", - "T188703-", - "C188704-", - "G188705-", - "C188706-", - "A188707-", - "T188708-", - "T188709-", - "G188710-", - "A188711-", - "C188712-", - "T188713-", - "T188714-", - "T188715-", - "A188716-", - "C188717-", - "A188718-", - "C188719-", - "A188720-", - "G188721-", - "A188722-", - "C188723-", - "A188724-", - "T188725-", - "G188726-", - "A188727-", - "A188728-", - "C188729-", - "A188730-", - "T188731-", - "C188732-", - "C188733-", - "C188734-", - "C188735-", - "T188736-", - "G188737-", - "A188738-", - "A188739-", - "T188740-", - "C188741-", - "T188742-", - "G188743-", - "T188744-", - "A188745-", - "C188746-", - "A188747-", - "T188748-", - "A188749-", - "C188750-", - "T188751-", - "T188752-", - "T188753-", - "G188754-", - "T188755-", - "G188756-", - "G188757-", - "A188758-", - "T188759-", - "T188760-", - "T188761-", - "A188762-", - "C188763-", - "A188764-", - "C188765-", - "T188766-", - "G188767-", - "T188768-", - "T188769-", - "A188770-", - "G188771-", - "A188772-", - "A188773-", - "T188774-", - "C188775-", - "T188776-", - "C188777-", - "T188778-", - "A188779-", - "A188780-", - "C188781-", - "G188782-", - "C188783-", - "T188784-", - "G188785-", - "G188786-", - "C188787-", - "C188788-", - "T188789-", - "C188790-", - "T188791-", - "G188792-", - "T188793-", - "T188794-", - "G188795-", - "T188796-", - "T188797-", - "A188798-", - "C188799-", - "T188800-", - "T188801-", - "T188802-", - "C188803-", - "T188804-", - "A188805-", - "T188806-", - "G188807-", - "A188808-", - "T188809-", - "G188810-", - "C188811-", - "A188812-", - "C188813-", - "G188814-", - "T188815-", - "A188816-", - "T188817-", - "C188818-", - "G188819-", - "T188820-", - "T188821-", - "A188822-", - "T188823-", - "G188824-", - "C188825-", - "A188826-", - "A188827-", - "G188828-", - "C188829-", - "T188830-", - "T188831-", - "T188832-", - "C188833-", - "A188834-", - "T188835-", - "G188836-", - "T188837-", - "T188838-", - "G188839-", - "A188840-", - "C188841-", - "T188842-", - "A188843-", - "C188844-", - "T188845-", - "G188846-", - "C188847-", - "A188848-", - "G188849-", - "T188850-", - "G188851-", - "T188852-", - "T188853-", - "T188854-", - "C188855-", - "T188856-", - "T188857-", - "G188858-", - "C188859-", - "T188860-", - "C188861-", - "T188862-", - "G188863-", - "A188864-", - "C188865-", - "T188866-", - "A188867-", - "C188868-", - "A188869-", - "T188870-", - "A188871-", - "T188872-", - "A188873-", - "C188874-", - "T188875-", - "C188876-", - "T188877-", - "A188878-", - "C188879-", - "A188880-", - "A188881-", - "T188882-", - "C188883-", - "A188884-", - "A188885-", - "A188886-", - "G188887-", - "A188888-", - "A188890-", - "G188891-", - "A188892-", - "T188893-", - "T188894-", - "T188895-", - "C188896-", - "A188897-", - "G188898-", - "T188899-", - "A188900-", - "A188901-", - "A188902-", - "C188903-", - "T188904-", - "T188905-", - "G188906-", - "T188907-", - "A188908-", - "A188909-", - "C188910-", - "A188911-", - "G188912-", - "G188913-", - "A188914-", - "T188915-", - "T188916-", - "G188917-", - "T188918-", - "T188919-", - "T188920-", - "G188921-", - "C188922-", - "T188923-", - "G188924-", - "C188925-", - "T188926-", - "T188927-", - "T188928-", - "C188929-", - "T188930-", - "G188931-", - "G188932-", - "A188933-", - "T188934-", - "T188935-", - "T188936-", - "T188937-", - "A188938-", - "A188939-", - "T188940-", - "T188941-", - "T188942-", - "T188943-", - "G188944-", - "T188945-", - "C188946-", - "A188947-", - "G188948-", - "G188949-", - "A188950-", - "G188951-", - "T188952-", - "C188953-", - "T188954-", - "T188955-", - "G188956-", - "A188957-", - "G188958-", - "G188959-", - "A188960-", - "T188961-", - "A188962-", - "A188963-", - "A188964-", - "G188965-", - "T188966-", - "T188967-", - "T188968-", - "A188969-", - "A188970-", - "A188971-", - "A188972-", - "T188973-", - "A188974-", - "G188975-", - "A188976-", - "A188977-", - "T188978-", - "T188979-", - "A188980-", - "A188981-", - "T188982-", - "A188983-", - "A188984-", - "A188985-", - "G188986-", - "A188987-", - "A188988-", - "C188989-", - "A188990-", - "T188991-", - "A188992-", - "T188993-", - "A188994-", - "G188995-", - "G188996-", - "T188997-", - "C188998-", - "A188999-", - "T189000-", - "T189001-", - "T189002-", - "T189003-", - "T189004-", - "T189005-", - "A189006-", - "A189007-", - "A189008-", - "C189009-", - "A189010-", - "T189011-", - "G189012-", - "G189013-", - "A189014-", - "T189015-", - "A189016-", - "G189017-", - "A189018-", - "A189019-", - "A189020-", - "C189021-", - "C189022-", - "A189023-", - "A190128-", - "T190129-", - "A190130-", - "T190131-", - "T190132-", - "A190133-", - "T190134-", - "T190135-", - "A190136-", - "A190137-", - "T190138-", - "G190139-", - "G190140-", - "A190141-", - "T190142-", - "A190143-", - "T190144-", - "A190145-", - "T190146-", - "A190147-", - "G190148-", - "A190149-", - "T190150-", - "A190151-", - "A190152-", - "C190153-", - "G190154-", - "C190155-", - "A190156-", - "A190157-", - "T190158-", - "A190159-", - "G190160-", - "G190161-", - "G190162-", - "A190163-", - "C190164-", - "T190165-", - "A190166-", - "A190167-", - "T190168-", - "A190169-", - "G190170-", - "T190171-", - "A190172-", - "T190173-", - "T190174-", - "G190175-", - "T190176-", - "A190177-", - "A190178-", - "A190179-", - "A190180-", - "G190181-", - "G190345A" - ], - "OPG071": [ - "R246Q" - ], - "OPG192": [ - "D39X", - "N40-", - "I41-", - "E42-", - "N43-", - "S44-", - "Y45-", - "T46-", - "D47-", - "D48-", - "N49-", - "N50-", - "E51-", - "L52-", - "V53-", - "L54-", - "N55-", - "F56-", - "K57-", - "E58-", - "Y59-", - "T60-", - "I61-", - "S62-", - "I63-", - "I64-", - "T65-", - "E66-", - "S67-", - "C68-", - "D69-", - "V70-", - "G71-", - "F72-", - "D73-", - "S74-", - "I75-", - "D76-", - "I77-", - "D78-", - "V79-", - "I80-", - "N81-", - "D82-", - "Y83-", - "*183X" - ], - "OPG195": [ - "T118N", - "L119-", - "C120-", - "I121-", - "S122-", - "V123-", - "Y124-", - "C125-", - "D126-", - "Q127X", - "E128Q", - "A129-", - "G130-", - "D131-", - "I132-", - "K133-", - "F134-", - "E135-", - "E136-", - "Y137-", - "T138-", - "Q139-", - "E140-", - "S141-", - "S142-", - "D143-", - "I144-", - "S145-", - "I146-", - "K149L", - "Y150-", - "D151-", - "S152-", - "S153-", - "C154-", - "I155-", - "D156-", - "Y157-", - "L158-", - "G159-", - "I160-", - "N161-", - "Q162-", - "S163-", - "F164-", - "M165-", - "N166-", - "C168H", - "I169F", - "R170G", - "R171X", - "I172X", - "T174R", - "D176-", - "R177-", - "E178-", - "S179-", - "C180-", - "V181-", - "R182-", - "I183S", - "*222X" - ], - "OPG197": [ - "M1-", - "Y2-", - "S3-", - "G4-", - "I5-", - "Y6-", - "P7-", - "I8-", - "V9-", - "L10-", - "L11-", - "L12-", - "T13-", - "T14-", - "N15-", - "M16-", - "D19-", - "T20-", - "D21-", - "T22-", - "D23-", - "T24-", - "D25-", - "T26-", - "D27-", - "T28-", - "D29X", - "*101X" - ] - }, - "labels": { - "aa": "OPG071: R246Q; OPG192: D39X, N40-, I41-, E42-, N43-, S44-, Y45-, T46-, D47-, D48-, N49-, N50-, E51-, L52-, V53-, L54-, N55-, F56-, K57-, E58-, Y59-, T60-, I61-, S62-, I63-, I64-, T65-, E66-, S67-, C68-, D69-, V70-, G71-, F72-, D73-, S74-, I75-, D76-, I77-, D78-, V79-, I80-, N81-, D82-, Y83-, *183X; OPG195: T118N, L119-, C120-, I121-, S122-, V123-, Y124-, C125-, D126-, Q127X, E128Q, A129-, G130-, D131-, I132-, K133-, F134-, E135-, E136-, Y137-, T138-, Q139-, E140-, S141-, S142-, D143-, I144-, S145-, I146-, K149L, Y150-, D151-, S152-, S153-, C154-, I155-, D156-, Y157-, L158-, G159-, I160-, N161-, Q162-, S163-, F164-, M165-, N166-, C168H, I169F, R170G, R171X, I172X, T174R, D176-, R177-, E178-, S179-, C180-, V181-, R182-, I183S, *222X; OPG197: M1-, Y2-, S3-, G4-, I5-, Y6-, P7-, I8-, V9-, L10-, L11-, L12-, T13-, T14-, N15-, M16-, D19-, T20-, D21-, T22-, D23-, T24-, D25-, T26-, D27-, T28-, D29X, *101X" - } - } - }, - { - "name": "NODE_0000083", - "node_attrs": { - "div": 514, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C23353T", - "C51809T", - "G69678A", - "C125492T", - "C128174T", - "-188889A" - ], - "OPG039": [ - "D256N" - ], - "OPG071": [ - "R877Q" - ], - "OPG146": [ - "D50N" - ] - }, - "labels": { - "aa": "OPG039: D256N; OPG071: R877Q; OPG146: D50N" - } - }, - "children": [ - { - "name": "NODE_0000084", - "node_attrs": { - "div": 515, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T27971C", - "A169727T", - "-173274A", - "-173275T", - "-173276A", - "-173277T", - "-173278A", - "-173279T", - "-173280A", - "-173281T", - "-173282A", - "-173283T", - "-173284A", - "-173285T" - ], - "OPG197": [ - "T20S" - ] - }, - "labels": { - "aa": "OPG197: T20S" - } - }, - "children": [ - { - "name": "MK783033", - "node_attrs": { - "div": 525, - "author": { - "author": "Yinka-Ogunleye,A., Aruna,O., Dalhat,M., Ogoina,D., McCollum,A., Disu,Y., Mamadu,I., Akinpelu,A., Ahmad,A., Burga,J., Ndoreraho,A., Nkunzimana,E., Manneh,L., Mohammed,A., Adeoye,O., Tom-Aba,D., Silenou,B., Ipadeola,O., Saleh,M., Adeyemo,A., Nwadiutor,I., Aworabhi,N., Uke,P., John,D., Wakama,P., Reynolds,M., Mauldin,M., Doty,J., Wilkins,K., Musa,J., Khalakdina,A., Adedeji,A., Mba,N., Ojo,O., Krause,G., Ihekweazu,C., Mauldin,M.R., Li,Y., Gao,J.", - "value": "Yinka-Ogunleye,A., Aruna,O., Dalhat,M., Ogoina,D., McCollum,A., Disu,Y., Mamadu,I., Akinpelu,A., Ahmad,A., Burga,J., Ndoreraho,A., Nkunzimana,E., Manneh,L., Mohammed,A., Adeoye,O., Tom-Aba,D., Silenou,B., Ipadeola,O., Saleh,M., Adeyemo,A., Nwadiutor,I., Aworabhi,N., Uke,P., John,D., Wakama,P., Reynolds,M., Mauldin,M., Doty,J., Wilkins,K., Musa,J., Khalakdina,A., Adedeji,A., Mba,N., Ojo,O., Krause,G., Ihekweazu,C., Mauldin,M.R., Li,Y., Gao,J." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "CDC, NCEZID/DHCPP/PRB" - }, - "date": { - "value": "2017-10-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.3" - }, - "strain_original": { - "value": "MK783033" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "MK783033" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "C25731T", - "C25768T", - "C26020T", - "A56968G", - "G102267T", - "C117099T", - "G129583A", - "C155707T", - "G161701A", - "-169718G", - "-169719A", - "-169720T", - "-169721T", - "-169722C", - "-169723A", - "T169727A", - "T187428C", - "-196602A" - ], - "OPG042": [ - "D360N" - ], - "OPG074": [ - "L53S" - ], - "OPG121": [ - "G160C" - ], - "OPG136": [ - "R830Q" - ], - "OPG188": [ - "V36I" - ], - "OPG197": [ - "-17D", - "-18S", - "S20T" - ] - }, - "labels": { - "aa": "OPG042: D360N; OPG074: L53S; OPG121: G160C; OPG136: R830Q; OPG188: V36I; OPG197: -17D, -18S, S20T" - } - } - }, - { - "name": "MPXV_Nigeria_2017_2948", - "node_attrs": { - "div": 515, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "date": { - "value": "2017-10-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.3" - }, - "strain_original": { - "value": "MPXV_Nigeria_2017_2948" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP535323" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV_Nigeria_2017_2947", - "node_attrs": { - "div": 515, - "author": { - "author": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y.", - "value": "Nnaemeka,N., Akanbi,O., Chukwu,C., Ayansola,O., Ahmad,A., Yinka-Ogunleye,A., Akinpelu,A., Babatunde,O., Ihekweazu,C., Adetifa,I., Mauldin,M.R., Gigante,C.M., Batra,D., Weigand,M.R., Howard,D.T., Sheth,M., Seabolt,M.H., Li,Y." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Nigeria Centre for Disease Control, National Reference Laboratory" - }, - "date": { - "value": "2017-10-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.3" - }, - "strain_original": { - "value": "MPXV_Nigeria_2017_2947" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP535335" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000085", - "node_attrs": { - "div": 519, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T595-", - "C92053T", - "C123000T", - "C146052T", - "-146862T", - "-146863A", - "-146864T", - "-146865T", - "-146866T", - "-146867T", - "-146868A", - "-146869T", - "-146870A", - "-146871T", - "-146872T", - "-146873T", - "-146874T", - "-146875A", - "-146876T", - "-146877A", - "-146878T", - "-146879T", - "-146880T", - "C150831T", - "C151305T", - "-169718G", - "-169719A", - "-169720T", - "-169721T", - "-169722C", - "-169723A" - ], - "OPG113": [ - "S108L" - ], - "OPG143": [ - "E106K" - ], - "OPG197": [ - "-17D", - "-18S" - ] - }, - "labels": { - "aa": "OPG113: S108L; OPG143: E106K; OPG197: -17D, -18S" - } - }, - "children": [ - { - "name": "MPXV/015/19", - "node_attrs": { - "div": 522, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "date": { - "value": "2019-03-14" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.3" - }, - "strain_original": { - "value": "MPXV/015/19" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP612677" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C56351T", - "G74032A", - "T76079-", - "A89100-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "A173300-", - "T173301-", - "G190782A" - ], - "NBT03_gp174": [ - "E125K" - ], - "OPG074": [ - "E259K" - ], - "OPG094": [ - "A85T" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG109": [ - "F116X", - "*796X" - ] - }, - "labels": { - "aa": "NBT03_gp174: E125K; OPG074: E259K; OPG094: A85T; OPG097: K266X, *345X; OPG109: F116X, *796X" - } - } - }, - { - "name": "NODE_0000086", - "node_attrs": { - "div": 548, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C2930T", - "C18493T", - "C18908T", - "G21898A", - "G23626A", - "C25254T", - "C29199T", - "G36901A", - "G44085A", - "G63034A", - "G75099A", - "G75144A", - "G76509A", - "C87659T", - "G115332A", - "C115572T", - "G122627A", - "C128771T", - "C140739T", - "A149394-", - "G151519T", - "G151875A", - "C160008T", - "C160312T", - "G165130A", - "G168862A", - "-173274A", - "-173275T", - "-173276A", - "-173277T", - "-173278A", - "-173279T", - "-173280A", - "-173281T", - "-173282A", - "-173283T", - "-173284A", - "-173285T", - "G174491A", - "G176289A", - "G176366A", - "C177703T", - "G194280A", - "A196603-", - "A196604-" - ], - "OPG003": [ - "E560K" - ], - "OPG037": [ - "S179L" - ], - "OPG039": [ - "H165Y" - ], - "OPG045": [ - "E22K" - ], - "OPG064": [ - "S605L" - ], - "OPG082": [ - "S140L" - ], - "OPG097": [ - "H123Y" - ], - "OPG109": [ - "E597K" - ], - "OPG133": [ - "R42Q", - "S122F" - ], - "OPG143": [ - "T230M" - ], - "OPG174": [ - "M1X", - "*347X" - ], - "OPG178": [ - "G4V", - "D123N" - ], - "OPG205": [ - "A212T", - "M237I", - "S683L" - ] - }, - "labels": { - "aa": "OPG003: E560K; OPG037: S179L; OPG039: H165Y; OPG045: E22K; OPG064: S605L; OPG082: S140L; OPG097: H123Y; OPG109: E597K; OPG133: R42Q, S122F; OPG143: T230M; OPG174: M1X, *347X; OPG178: G4V, D123N; OPG205: A212T, M237I, S683L" - } - }, - "children": [ - { - "name": "9000360", - "node_attrs": { - "div": 548, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.3" - }, - "strain_original": { - "value": "9000360" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP413718" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133169-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-" - ] - } - } - }, - { - "name": "9000450", - "node_attrs": { - "div": 548, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.3" - }, - "strain_original": { - "value": "9000450" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536812" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000087", - "node_attrs": { - "div": 513, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C23564T", - "C72362T", - "C83326T", - "G87230A", - "G87297A", - "G91728A", - "C119296T", - "C121320T", - "G125249A", - "-146862T", - "-146863A", - "-146864T", - "-146865T", - "-146866T", - "-146867T", - "-146868A", - "-146869T", - "-146870A", - "-146871T", - "-146872T", - "-146873T", - "-146874T", - "-146875A", - "-146876T", - "-146877A", - "-146878T", - "-146879T", - "-146880T", - "G148412A", - "C164832T", - "C168120T", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-" - ], - "OPG092": [ - "D196N" - ], - "OPG105": [ - "S734L" - ], - "OPG109": [ - "H740Y" - ], - "OPG136": [ - "D98N" - ], - "OPG139": [ - "A17T" - ], - "OPG145": [ - "E435K" - ], - "OPG193": [ - "L263F" - ] - }, - "labels": { - "aa": "OPG092: D196N; OPG105: S734L; OPG109: H740Y; OPG136: D98N; OPG139: A17T; OPG145: E435K; OPG193: L263F", - "clade": "A.1" - } - }, - "children": [ - { - "name": "MN648051", - "node_attrs": { - "div": 517, - "author": { - "author": "Cohen Gihon,I., Israeli,O., Shifman,O., Erez,N., Melamed,S., Paran,N., Beth-Din,A., Zvi,A.", - "value": "Cohen Gihon,I., Israeli,O., Shifman,O., Erez,N., Melamed,S., Paran,N., Beth-Din,A., Zvi,A." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel" - }, - "date": { - "value": "2018-10-04" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "strain_original": { - "value": "MN648051" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "MN648051" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Israel" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T595-", - "C8772T", - "C91363T", - "T133094-", - "T133095-", - "T133096-", - "T133097-", - "T133098-", - "T133099-", - "A147593T", - "G150568A", - "-173278A", - "-173279T", - "-173280A", - "-173281T", - "-173282A", - "-173283T", - "-173284A", - "-173285T", - "-173286A", - "-173287T", - "-173288A", - "-173289T", - "-173290A", - "-173291T", - "-173292A", - "-173293T", - "-173294A", - "-173295T", - "-173296A", - "-173297T", - "-173298A", - "-173299T", - "G177273A", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A196603-" - ], - "OPG172": [ - "E56V" - ], - "OPG205": [ - "D540N" - ] - }, - "labels": { - "aa": "OPG172: E56V; OPG205: D540N" - } - } - }, - { - "name": "MPXV-UK_P1", - "node_attrs": { - "div": 516, - "author": { - "author": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y.", - "value": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "date": { - "value": "2018-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "strain_original": { - "value": "MPXV-UK_P1" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "MT903343" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "G28838A", - "G92349A", - "-173274A", - "-173275T", - "-173276A", - "-173277T", - "-173278A", - "-173279T", - "-173280A", - "-173281T", - "-173282A", - "-173283T", - "-173284A", - "-173285T", - "-173286A", - "-173287T", - "-173288A", - "-173289T", - "-173290A", - "-173291T", - "-173292A", - "-173293T", - "-173294A", - "-173295T", - "-173296A", - "-173297T", - "-173298A", - "-173299T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "G188494A", - "-196602A" - ], - "OPG045": [ - "A142V" - ], - "OPG113": [ - "E207K" - ] - }, - "labels": { - "aa": "OPG045: A142V; OPG113: E207K" - } - } - }, - { - "name": "MPXV-M5320_M15_Bayelsa", - "node_attrs": { - "div": 515, - "author": { - "author": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y.", - "value": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "date": { - "value": "2018-08-14" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "strain_original": { - "value": "MPXV-M5320_M15_Bayelsa" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "MT903341" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "A3152-", - "G3153-", - "A3154-", - "T3155-", - "T3156-", - "C3157-", - "G3158-", - "A3159-", - "A3160-", - "T3161-", - "C3162-", - "T3163-", - "C3164-", - "T3165-", - "T3166-", - "T3167-", - "G3168-", - "A3169-", - "G3170-", - "G3171-", - "A3172-", - "G3173-", - "A3174-", - "C3175-", - "T3176-", - "T3177-", - "A3178-", - "T3179-", - "G3180-", - "T3181-", - "C3182-", - "A3183-", - "C3184-", - "G3185-", - "A3186-", - "C3187-", - "T3188-", - "A3189-", - "C3190-", - "A3191-", - "T3192-", - "T3193-", - "T3194-", - "T3195-", - "T3196-", - "C3197-", - "G3198-", - "A3199-", - "T3200-", - "G3201-", - "A3202-", - "T3203-", - "G3204-", - "G3205-", - "A3206-", - "A3207-", - "T3208-", - "C3209-", - "T3210-", - "A3211-", - "T3212-", - "C3213-", - "T3214-", - "T3215-", - "A3216-", - "T3217-", - "C3218-", - "G3219-", - "A3220-", - "A3221-", - "T3222-", - "G3223-", - "A3224-", - "T3225-", - "A3226-", - "T3227-", - "A3228-", - "T3229-", - "T3230-", - "T3231-", - "T3232-", - "T3233-", - "C3234-", - "A3235-", - "T3236-", - "A3237-", - "A3238-", - "A3239-", - "T3240-", - "A3241-", - "C3242-", - "A3243-", - "C3244-", - "T3245-", - "T3246-", - "T3247-", - "T3248-", - "A3249-", - "T3250-", - "A3251-", - "G3252-", - "T3253-", - "C3254-", - "C3255-", - "T3256-", - "C3257-", - "G3258-", - "T3259-", - "T3260-", - "T3261-", - "A3262-", - "A3263-", - "A3264-", - "C3265-", - "A3266-", - "G3267-", - "A3268-", - "A3269-", - "T3270-", - "T3271-", - "T3272-", - "A3273-", - "G3274-", - "T3275-", - "A3276-", - "T3277-", - "G3278-", - "T3279-", - "A3280-", - "G3281-", - "T3282-", - "T3283-", - "C3284-", - "C3285-", - "G3286-", - "C3287-", - "A3288-", - "A3289-", - "A3290-", - "T3291-", - "G3292-", - "A3293-", - "C3294-", - "T3295-", - "C3296-", - "G3297-", - "T3298-", - "C3299-", - "C3300-", - "C3301-", - "T3302-", - "T3303-", - "A3304-", - "A3305-", - "T3306-", - "A3307-", - "G3308-", - "G3309-", - "C3310-", - "A3311-", - "G3312-", - "T3313-", - "A3314-", - "G3315-", - "G3316-", - "C3317-", - "T3318-", - "A3319-", - "T3320-", - "T3321-", - "A3322-", - "T3323-", - "C3324-", - "T3325-", - "T3326-", - "C3327-", - "T3328-", - "T3329-", - "T3330-", - "A3331-", - "C3332-", - "G3333-", - "T3334-", - "A3335-", - "G3336-", - "T3337-", - "G3338-", - "A3339-", - "T3340-", - "C3341-", - "G3342-", - "T3343-", - "C3344-", - "G3345-", - "T3346-", - "A3347-", - "G3348-", - "G3349-", - "G3350-", - "A3351-", - "G3352-", - "A3353-", - "G3354-", - "A3355-", - "A3356-", - "C3357-", - "T3358-", - "C3359-", - "C3360-", - "G3361-", - "A3362-", - "C3363-", - "A3364-", - "T3365-", - "C3366-", - "T3367-", - "T3368-", - "G3369-", - "T3370-", - "A3371-", - "G3372-", - "A3373-", - "A3374-", - "C3375-", - "A3376-", - "A3377-", - "C3378-", - "G3379-", - "A3380-", - "T3381-", - "T3382-", - "T3383-", - "A3384-", - "A3385-", - "T3386-", - "C3387-", - "A3388-", - "T3389-", - "A3390-", - "G3391-", - "G3392-", - "T3393-", - "A3394-", - "G3395-", - "A3396-", - "G3397-", - "A3398-", - "T3399-", - "A3400-", - "C3401-", - "T3402-", - "T3403-", - "T3404-", - "C3405-", - "A3406-", - "G3407-", - "T3408-", - "C3409-", - "T3410-", - "G3411-", - "T3412-", - "G3413-", - "G3414-", - "T3415-", - "G3416-", - "G3417-", - "A3418-", - "T3419-", - "A3420-", - "A3421-", - "T3422-", - "G3423-", - "T3424-", - "C3425-", - "A3426-", - "T3427-", - "T3428-", - "A3429-", - "A3430-", - "C3431-", - "G3432-", - "A3433-", - "C3434-", - "A3435-", - "T3436-", - "C3437-", - "C3438-", - "G3439-", - "C3440-", - "C3441-", - "T3442-", - "T3443-", - "G3444-", - "T3445-", - "A3446-", - "T3447-", - "A3448-", - "T3449-", - "A3450-", - "A3451-", - "T3452-", - "G3453-", - "T3454-", - "T3455-", - "T3456-", - "C3457-", - "T3458-", - "G3459-", - "T3460-", - "T3461-", - "T3462-", - "T3463-", - "C3464-", - "A3465-", - "A3466-", - "A3467-", - "C3468-", - "A3469-", - "C3470-", - "C3471-", - "A3472-", - "A3473-", - "G3474-", - "T3475-", - "C3476-", - "G3477-", - "A3478-", - "A3479-", - "T3480-", - "A3481-", - "C3482-", - "T3483-", - "G3484-", - "T3485-", - "C3486-", - "T3487-", - "T3488-", - "A3489-", - "T3490-", - "C3491-", - "G3492-", - "T3493-", - "C3494-", - "T3495-", - "T3496-", - "T3497-", - "A3498-", - "G3499-", - "T3500-", - "C3501-", - "G3502-", - "G3503-", - "A3504-", - "A3505-", - "G3506-", - "G3507-", - "T3508-", - "T3509-", - "G3510-", - "A3511-", - "T3512-", - "G3513-", - "T3514-", - "C3515-", - "G3516-", - "T3517-", - "A3518-", - "T3519-", - "C3520-", - "C3521-", - "G3522-", - "A3523-", - "T3524-", - "G3525-", - "T3526-", - "A3527-", - "T3528-", - "A3529-", - "C3530-", - "G3531-", - "A3532-", - "G3533-", - "G3534-", - "T3535-", - "A3536-", - "T3537-", - "G3538-", - "A3539-", - "G3540-", - "G3541-", - "C3542-", - "A3543-", - "A3544-", - "C3545-", - "A3546-", - "T3547-", - "T3548-", - "G3549-", - "T3550-", - "T3551-", - "A3552-", - "T3553-", - "T3554-", - "G3555-", - "C3556-", - "A3557-", - "A3558-", - "T3559-", - "T3560-", - "C3561-", - "T3562-", - "G3563-", - "G3564-", - "A3565-", - "A3566-", - "G3567-", - "G3568-", - "C3569-", - "G3570-", - "G3571-", - "T3572-", - "A3573-", - "T3574-", - "G3575-", - "A3576-", - "A3577-", - "G3578-", - "A3579-", - "G3580-", - "G3581-", - "A3582-", - "G3583-", - "T3584-", - "C3585-", - "A3586-", - "T3587-", - "T3588-", - "G3589-", - "T3590-", - "A3591-", - "T3592-", - "T3593-", - "A3594-", - "T3595-", - "A3596-", - "G3597-", - "T3598-", - "A3599-", - "T3600-", - "T3601-", - "C3602-", - "G3603-", - "T3604-", - "C3605-", - "T3606-", - "T3607-", - "T3608-", - "C3609-", - "T3610-", - "G3611-", - "A3612-", - "A3613-", - "T3614-", - "G3615-", - "T3616-", - "C3617-", - "G3618-", - "A3619-", - "A3620-", - "T3621-", - "C3622-", - "T3623-", - "A3624-", - "T3625-", - "C3626-", - "T3627-", - "A3628-", - "G3629-", - "T3630-", - "A3631-", - "G3632-", - "A3633-", - "T3634-", - "A3635-", - "C3636-", - "C3637-", - "G3638-", - "T3639-", - "A3640-", - "G3641-", - "T3642-", - "A3643-", - "T3644-", - "A3645-", - "T3646-", - "T3647-", - "G3648-", - "A3649-", - "G3650-", - "A3651-", - "G3652-", - "A3653-", - "G3654-", - "C3655-", - "G3656-", - "A3657-", - "C3658-", - "T3659-", - "T3660-", - "C3661-", - "C3662-", - "A3663-", - "T3664-", - "A3665-", - "T3666-", - "C3667-", - "C3668-", - "T3669-", - "T3670-", - "G3671-", - "A3672-", - "T3673-", - "T3674-", - "A3675-", - "T3676-", - "G3677-", - "T3678-", - "T3679-", - "T3680-", - "T3681-", - "A3682-", - "T3683-", - "G3684-", - "A3685-", - "A3686-", - "T3687-", - "A3688-", - "G3689-", - "A3690-", - "T3691-", - "A3692-", - "A3693-", - "A3694-", - "G3695-", - "T3696-", - "A3697-", - "G3698-", - "A3699-", - "T3700-", - "G3701-", - "T3702-", - "T3703-", - "G3704-", - "T3705-", - "C3706-", - "C3707-", - "T3708-", - "T3709-", - "C3710-", - "T3711-", - "T3712-", - "C3713-", - "C3714-", - "T3715-", - "T3716-", - "T3717-", - "T3718-", - "G3719-", - "T3720-", - "A3721-", - "A3722-", - "T3723-", - "T3724-", - "T3725-", - "C3726-", - "C3727-", - "C3728-", - "G3729-", - "T3730-", - "A3731-", - "T3732-", - "T3733-", - "T3734-", - "T3735-", - "T3736-", - "G3737-", - "T3738-", - "T3739-", - "C3740-", - "G3741-", - "T3742-", - "G3743-", - "C3744-", - "C3745-", - "A3746-", - "A3747-", - "T3748-", - "T3749-", - "G3750-", - "A3751-", - "G3752-", - "T3753-", - "A3754-", - "A3755-", - "C3756-", - "A3757-", - "T3758-", - "T3759-", - "A3760-", - "T3761-", - "G3762-", - "A3763-", - "G3764-", - "A3765-", - "A3766-", - "T3767-", - "A3768-", - "T3769-", - "G3770-", - "A3771-", - "C3772-", - "C3773-", - "T3774-", - "G3775-", - "T3776-", - "T3777-", - "G3778-", - "C3779-", - "A3780-", - "C3781-", - "A3782-", - "A3783-", - "T3784-", - "C3785-", - "G3786-", - "T3787-", - "T3788-", - "C3789-", - "T3790-", - "T3791-", - "T3792-", - "A3793-", - "T3794-", - "G3795-", - "T3796-", - "A3797-", - "T3798-", - "T3799-", - "C3800-", - "C3801-", - "A3802-", - "T3803-", - "G3804-", - "A3805-", - "T3806-", - "G3807-", - "G3808-", - "G3809-", - "T3810-", - "G3811-", - "T3812-", - "A3813-", - "C3814-", - "A3815-", - "A3816-", - "T3817-", - "C3818-", - "A3819-", - "A3820-", - "G3821-", - "A3822-", - "T3823-", - "T3824-", - "A3825-", - "T3826-", - "T3827-", - "A3828-", - "C3829-", - "G3830-", - "T3831-", - "A3832-", - "T3833-", - "C3834-", - "C3835-", - "T3836-", - "C3837-", - "G3838-", - "T3839-", - "A3840-", - "T3841-", - "C3842-", - "G3843-", - "G3844-", - "C3845-", - "T3846-", - "C3847-", - "C3848-", - "T3849-", - "C3850-", - "G3851-", - "A3852-", - "G3853-", - "A3854-", - "T3855-", - "A3856-", - "A3857-", - "A3858-", - "A3859-", - "G3860-", - "A3861-", - "G3862-", - "C3863-", - "A3864-", - "T3865-", - "A3866-", - "C3867-", - "A3868-", - "C3869-", - "C3870-", - "A3871-", - "C3872-", - "A3873-", - "C3874-", - "G3875-", - "A3876-", - "G3877-", - "G3878-", - "A3879-", - "C3880-", - "T3881-", - "A3882-", - "T3883-", - "G3884-", - "T3885-", - "T3886-", - "T3887-", - "G3888-", - "G3889-", - "T3890-", - "A3891-", - "T3892-", - "A3893-", - "C3894-", - "T3895-", - "G3896-", - "T3897-", - "T3898-", - "G3899-", - "A3900-", - "A3901-", - "G3902-", - "G3903-", - "T3904-", - "A3905-", - "A3906-", - "G3907-", - "T3908-", - "G3909-", - "T3910-", - "G3911-", - "T3912-", - "A3913-", - "A3914-", - "C3915-", - "G3916-", - "G3917-", - "C3918-", - "G3919-", - "T3920-", - "A3921-", - "T3922-", - "T3923-", - "T3924-", - "C3925-", - "C3926-", - "G3927-", - "A3928-", - "T3929-", - "T3930-", - "T3931-", - "T3932-", - "C3933-", - "G3934-", - "T3935-", - "A3936-", - "A3937-", - "C3938-", - "C3939-", - "G3940-", - "C3941-", - "G3942-", - "T3943-", - "T3944-", - "A3945-", - "A3946-", - "T3947-", - "G3948-", - "T3949-", - "T3950-", - "T3951-", - "G3952-", - "C3953-", - "T3954-", - "C3955-", - "C3956-", - "A3957-", - "T3958-", - "G3959-", - "A3960-", - "T3961-", - "C3962-", - "T3963-", - "A3964-", - "T3965-", - "T3966-", - "A3967-", - "T3968-", - "C3969-", - "G3970-", - "C3971-", - "G3972-", - "T3973-", - "A3974-", - "G3975-", - "A3976-", - "T3977-", - "G3978-", - "A3979-", - "A3980-", - "T3981-", - "C3982-", - "G3983-", - "C3984-", - "T3985-", - "T3986-", - "C3987-", - "T3988-", - "C3989-", - "A3990-", - "G3991-", - "C3992-", - "T3993-", - "C3994-", - "G3995-", - "C3996-", - "A3997-", - "T3998-", - "C3999-", - "T4000-", - "T4001-", - "A4002-", - "G4003-", - "T4004-", - "G4005-", - "T4006-", - "G4007-", - "A4008-", - "C4009-", - "T4010-", - "C4011-", - "T4012-", - "T4013-", - "T4014-", - "G4015-", - "A4016-", - "C4017-", - "T4018-", - "T4019-", - "G4020-", - "T4021-", - "A4022-", - "A4023-", - "T4024-", - "A4025-", - "A4026-", - "T4027-", - "T4028-", - "G4029-", - "C4030-", - "T4031-", - "T4032-", - "T4033-", - "C4034-", - "G4035-", - "T4036-", - "G4037-", - "G4038-", - "A4039-", - "A4040-", - "C4041-", - "G4042-", - "C4043-", - "G4044-", - "G4045-", - "A4046-", - "T4047-", - "A4048-", - "T4049-", - "G4050-", - "T4051-", - "G4052-", - "T4053-", - "T4054-", - "T4055-", - "A4056-", - "C4057-", - "A4058-", - "G4059-", - "T4060-", - "A4061-", - "G4062-", - "T4063-", - "A4064-", - "A4065-", - "T4066-", - "G4067-", - "A4068-", - "A4069-", - "G4070-", - "A4071-", - "G4072-", - "A4073-", - "A4074-", - "G4075-", - "T4076-", - "G4077-", - "A4078-", - "G4079-", - "T4080-", - "C4081-", - "C4082-", - "A4083-", - "T4084-", - "C4085-", - "C4086-", - "T4087-", - "C4088-", - "A4089-", - "T4090-", - "C4091-", - "G4092-", - "A4093-", - "C4094-", - "G4095-", - "C4096-", - "A4097-", - "A4098-", - "T4099-", - "T4100-", - "A4101-", - "G4102-", - "G4103-", - "G4104-", - "T4105-", - "C4106-", - "A4107-", - "G4108-", - "A4109-", - "T4110-", - "C4111-", - "C4112-", - "T4113-", - "T4114-", - "T4115-", - "A4116-", - "G4117-", - "T4118-", - "C4119-", - "A4120-", - "A4121-", - "T4122-", - "A4123-", - "A4124-", - "T4125-", - "T4126-", - "T4127-", - "G4128-", - "T4129-", - "A4130-", - "C4131-", - "A4132-", - "G4133-", - "A4134-", - "A4135-", - "C4136-", - "G4137-", - "T4138-", - "A4139-", - "A4140-", - "T4141-", - "A4142-", - "G4143-", - "T4144-", - "T4145-", - "T4146-", - "A4147-", - "A4148-", - "G4149-", - "C4150-", - "T4151-", - "C4152-", - "C4153-", - "C4154-", - "A4155-", - "T4156-", - "T4157-", - "G4158-", - "A4159-", - "A4160-", - "T4161-", - "T4162-", - "T4163-", - "A4164-", - "T4165-", - "A4166-", - "T4167-", - "C4168-", - "T4169-", - "A4170-", - "A4171-", - "G4172-", - "A4173-", - "T4174-", - "A4175-", - "A4176-", - "C4177-", - "A4178-", - "C4179-", - "A4180-", - "G4181-", - "C4182-", - "A4183-", - "A4184-", - "T4185-", - "A4186-", - "G4187-", - "A4188-", - "T4189-", - "C4190-", - "G4191-", - "G4192-", - "A4193-", - "T4194-", - "G4195-", - "A4196-", - "T4197-", - "T4198-", - "T4199-", - "A4200-", - "C4201-", - "T4202-", - "A4203-", - "A4204-", - "A4205-", - "G4206-", - "T4207-", - "C4208-", - "A4209-", - "T4210-", - "C4211-", - "A4212-", - "A4213-", - "T4214-", - "G4215-", - "G4216-", - "G4217-", - "G4218-", - "T4219-", - "C4220-", - "C4221-", - "G4222-", - "T4223-", - "T4224-", - "A4225-", - "G4226-", - "T4227-", - "A4228-", - "T4229-", - "A4230-", - "T4231-", - "C4232-", - "A4233-", - "A4234-", - "A4235-", - "G4236-", - "A4237-", - "T4238-", - "C4239-", - "T4240-", - "T4241-", - "G4242-", - "T4243-", - "T4244-", - "A4245-", - "T4246-", - "C4247-", - "G4248-", - "A4249-", - "T4250-", - "T4251-", - "G4252-", - "A4253-", - "T4254-", - "A4255-", - "G4256-", - "T4257-", - "G4258-", - "A4259-", - "A4260-", - "T4261-", - "G4262-", - "A4263-", - "A4264-", - "T4265-", - "C4266-", - "A4267-", - "G4268-", - "A4269-", - "T4270-", - "A4271-", - "G4272-", - "T4273-", - "G4274-", - "G4275-", - "T4276-", - "G4277-", - "T4278-", - "A4279-", - "G4280-", - "A4281-", - "G4282-", - "G4283-", - "A4284-", - "A4285-", - "T4286-", - "A4287-", - "T4288-", - "G4289-", - "T4290-", - "C4291-", - "C4292-", - "T4293-", - "T4294-", - "T4295-", - "T4296-", - "T4297-", - "T4298-", - "A4299-", - "T4300-", - "C4301-", - "C4302-", - "T4303-", - "T4304-", - "G4305-", - "C4306-", - "T4307-", - "A4308-", - "T4309-", - "C4310-", - "A4311-", - "A4312-", - "A4313-", - "G4314-", - "T4315-", - "T4316-", - "A4317-", - "C4318-", - "G4319-", - "C4320-", - "A4321-", - "T4322-", - "G4323-", - "C4324-", - "C4325-", - "G4326-", - "T4327-", - "G4328-", - "G4329-", - "C4330-", - "G4331-", - "T4332-", - "A4333-", - "A4334-", - "C4335-", - "A4336-", - "A4337-", - "T4338-", - "A4339-", - "T4340-", - "C4341-", - "T4342-", - "T4343-", - "T4344-", - "A4345-", - "A4346-", - "T4347-", - "A4348-", - "C4349-", - "A4350-", - "G4351-", - "A4352-", - "T4353-", - "G4354-", - "G4355-", - "A4356-", - "T4357-", - "T4358-", - "A4359-", - "A4360-", - "A4361-", - "T4362-", - "C4363-", - "G4364-", - "T4365-", - "G4366-", - "T4367-", - "A4368-", - "T4369-", - "T4370-", - "C4371-", - "A4372-", - "T4373-", - "C4374-", - "G4375-", - "T4376-", - "A4377-", - "T4378-", - "A4379-", - "G4380-", - "C4381-", - "A4382-", - "A4383-", - "T4384-", - "G4385-", - "T4386-", - "A4387-", - "A4388-", - "T4389-", - "G4390-", - "G4391-", - "A4392-", - "G4393-", - "A4394-", - "G4395-", - "T4396-", - "T4397-", - "A4398-", - "C4399-", - "C4400-", - "A4401-", - "C4402-", - "A4403-", - "T4404-", - "T4405-", - "T4406-", - "T4407-", - "A4408-", - "G4409-", - "T4410-", - "C4411-", - "G4412-", - "T4413-", - "T4414-", - "T4415-", - "A4416-", - "T4417-", - "T4418-", - "C4419-", - "A4420-", - "G4421-", - "A4422-", - "T4423-", - "C4424-", - "G4425-", - "C4426-", - "A4427-", - "G4428-", - "T4429-", - "G4430-", - "T4431-", - "T4432-", - "T4433-", - "A4434-", - "A4435-", - "T4436-", - "A4437-", - "A4438-", - "C4439-", - "T4440-", - "A4441-", - "A4442-", - "T4443-", - "T4444-", - "T4445-", - "A4446-", - "A4447-", - "A4448-", - "C4449-", - "A4450-", - "G4451-", - "A4452-", - "T4453-", - "G4454-", - "A4455-", - "G4456-", - "A4457-", - "T4458-", - "G4459-", - "A4460-", - "T4461-", - "A4462-", - "T4463-", - "A4464-", - "T4465-", - "C4466-", - "C4467-", - "A4468-", - "C4469-", - "A4470-", - "T4471-", - "C4472-", - "A4473-", - "A4474-", - "A4475-", - "G4476-", - "A4477-", - "A4478-", - "T4479-", - "G4480-", - "C4481-", - "G4482-", - "A4483-", - "G4484-", - "A4485-", - "T4486-", - "A4487-", - "C4488-", - "A4489-", - "T4490-", - "A4491-", - "T4492-", - "G4493-", - "A4494-", - "C4495-", - "A4496-", - "G4497-", - "A4498-", - "C4499-", - "A4500-", - "T4501-", - "T4502-", - "A4503-", - "T4504-", - "T4505-", - "G4506-", - "A4507-", - "C4508-", - "A4509-", - "G4510-", - "A4511-", - "A4512-", - "A4513-", - "T4514-", - "G4515-", - "T4516-", - "G4517-", - "A4518-", - "C4519-", - "C4520-", - "T4521-", - "T4522-", - "C4523-", - "A4524-", - "T4525-", - "T4526-", - "A4527-", - "T4528-", - "C4529-", - "A4530-", - "C4531-", - "C4532-", - "G4533-", - "T4534-", - "C4535-", - "G4536-", - "T4537-", - "C4538-", - "C4539-", - "A4540-", - "T4541-", - "A4542-", - "A4543-", - "A4544-", - "T4545-", - "G4546-", - "C4547-", - "G4548-", - "T4549-", - "T4550-", - "A4551-", - "G4552-", - "G4553-", - "T4554-", - "A4555-", - "C4556-", - "G4557-", - "T4558-", - "A4559-", - "C4560-", - "C4561-", - "A4562-", - "C4563-", - "A4564-", - "T4565-", - "A4566-", - "C4567-", - "T4568-", - "A4569-", - "T4570-", - "C4571-", - "G4572-", - "T4573-", - "T4574-", - "A4575-", - "A4576-", - "C4577-", - "G4578-", - "A4579-", - "T4580-", - "G4581-", - "C4582-", - "G4583-", - "C4584-", - "A4585-", - "C4586-", - "A4587-", - "A4588-", - "T4589-", - "C4590-", - "T4591-", - "C4592-", - "G4593-", - "T4594-", - "C4595-", - "C4596-", - "A4597-", - "T4598-", - "T4599-", - "T4600-", - "C4601-", - "A4602-", - "T4603-", - "C4604-", - "C4605-", - "A4606-", - "T4607-", - "C4608-", - "T4609-", - "T4610-", - "C4611-", - "A4612-", - "T4613-", - "A4614-", - "A4615-", - "T4616-", - "G4617-", - "A4618-", - "T4619-", - "T4620-", - "T4621-", - "A4622-", - "C4623-", - "T4624-", - "T4625-", - "T4626-", - "T4627-", - "T4628-", - "C4629-", - "A4630-", - "T4631-", - "A4632-", - "A4633-", - "T4634-", - "T4635-", - "A4636-", - "G4637-", - "A4638-", - "G4639-", - "A4640-", - "A4641-", - "A4642-", - "A4643-", - "A4644-", - "G4645-", - "A4646-", - "T4647-", - "C4648-", - "A4649-", - "A4650-", - "G4651-", - "G4652-", - "T4653-", - "A4654-", - "T4655-", - "A4656-", - "A4657-", - "A4658-", - "A4659-", - "A4660-", - "T4661-", - "T4662-", - "A4663-", - "G4664-", - "A4665-", - "A4666-", - "G4667-", - "T4668-", - "G4669-", - "T4670-", - "T4671-", - "A4672-", - "G4673-", - "A4674-", - "C4675-", - "T4676-", - "A4677-", - "T4678-", - "A4679-", - "A4680-", - "A4681-", - "C4682-", - "T4683-", - "A4684-", - "A4685-", - "C4686-", - "T4687-", - "T4688-", - "A4689-", - "T4690-", - "G4691-", - "A4692-", - "C4693-", - "T4694-", - "T4695-", - "A4696-", - "A4697-", - "C4698-", - "T4699-", - "A4700-", - "A4701-", - "C4702-", - "T4703-", - "T4704-", - "A4705-", - "T4706-", - "G4707-", - "A4708-", - "C4709-", - "T4710-", - "T4711-", - "A4712-", - "A4713-", - "C4714-", - "T4715-", - "A4716-", - "A4717-", - "C4718-", - "T4719-", - "T4720-", - "A4721-", - "T4722-", - "G4723-", - "A4724-", - "C4725-", - "T4726-", - "T4727-", - "A4728-", - "A4729-", - "C4730-", - "T4731-", - "A4732-", - "A4733-", - "C4734-", - "T4735-", - "T4736-", - "A4737-", - "T4738-", - "G4739-", - "A4740-", - "C4741-", - "T4742-", - "T4743-", - "A4744-", - "A4745-", - "C4746-", - "T4747-", - "A4748-", - "A4749-", - "C4750-", - "T4751-", - "T4752-", - "A4753-", - "T4754-", - "G4755-", - "A4756-", - "C4757-", - "T4758-", - "T4759-", - "A4760-", - "A4761-", - "C4762-", - "T4763-", - "A4764-", - "A4765-", - "C4766-", - "T4767-", - "T4768-", - "A4769-", - "T4770-", - "G4771-", - "A4772-", - "C4773-", - "T4774-", - "T4775-", - "A4776-", - "A4777-", - "C4778-", - "T4779-", - "A4780-", - "A4781-", - "C4782-", - "T4783-", - "T4784-", - "A4785-", - "T4786-", - "G4787-", - "A4788-", - "C4789-", - "T4790-", - "T4791-", - "A4792-", - "A4793-", - "C4794-", - "T4795-", - "A4796-", - "A4797-", - "C4798-", - "T4799-", - "T4800-", - "A4801-", - "T4802-", - "G4803-", - "A4804-", - "C4805-", - "T4806-", - "A4807-", - "T4808-", - "T4809-", - "A4810-", - "A4811-", - "C4812-", - "T4813-", - "C4814-", - "A4815-", - "T4816-", - "T4817-", - "T4818-", - "C4819-", - "A4820-", - "A4821-", - "G4822-", - "A4823-", - "A4824-", - "A4825-", - "G4826-", - "G4827-", - "T4828-", - "G4829-", - "G4830-", - "G4831-", - "T4832-", - "G4833-", - "G4834-", - "A4835-", - "T4836-", - "A4837-", - "G4838-", - "A4839-", - "A4840-", - "C4841-", - "T4842-", - "C4843-", - "T4844-", - "A4845-", - "T4846-", - "A4847-", - "T4848-", - "G4849-", - "A4850-", - "C4851-", - "A4852-", - "G4853-", - "C4854-", - "T4855-", - "T4856-", - "G4857-", - "T4858-", - "G4859-", - "A4860-", - "A4861-", - "A4862-", - "C4863-", - "A4864-", - "A4865-", - "T4866-", - "T4867-", - "A4868-", - "G4869-", - "A4870-", - "T4871-", - "C4872-", - "C4873-", - "C4874-", - "T4875-", - "A4876-", - "A4877-", - "T4878-", - "T4879-", - "T4880-", - "C4881-", - "T4882-", - "A4883-", - "A4884-", - "T4885-", - "G4886-", - "G4887-", - "A4888-", - "A4889-", - "G4890-", - "T4891-", - "T4892-", - "T4893-", - "T4894-", - "G4895-", - "A4896-", - "T4897-", - "A4898-", - "G4899-", - "G4900-", - "A4901-", - "G4902-", - "A4903-", - "T4904-", - "T4905-", - "G4906-", - "T4907-", - "C4908-", - "A4909-", - "T4910-", - "C4911-", - "A4912-", - "G4913-", - "T4914-", - "T4915-", - "G4916-", - "A4917-", - "T4918-", - "A4919-", - "C4920-", - "A4921-", - "T4922-", - "T4923-", - "G4924-", - "T4925-", - "T4926-", - "T4927-", - "A4928-", - "T4929-", - "T4930-", - "A4931-", - "T4932-", - "C4933-", - "T4934-", - "C4935-", - "A4936-", - "T4937-", - "C4938-", - "T4939-", - "A4940-", - "T4941-", - "T4942-", - "A4943-", - "G4944-", - "A4945-", - "G4946-", - "C4947-", - "A4948-", - "C4949-", - "G4950-", - "T4951-", - "C4952-", - "T4953-", - "G4954-", - "T4955-", - "T4956-", - "T4957-", - "A4958-", - "G4959-", - "A4960-", - "G4961-", - "C4962-", - "T4963-", - "T4964-", - "T4965-", - "A4966-", - "G4967-", - "T4968-", - "G4969-", - "A4970-", - "C4971-", - "C4972-", - "T4973-", - "G4974-", - "C4975-", - "T4976-", - "C4977-", - "G4978-", - "G4979-", - "T4980-", - "T4981-", - "A4982-", - "C4983-", - "T4984-", - "T4985-", - "C4986-", - "T4987-", - "G4988-", - "T4989-", - "G4990-", - "T4991-", - "A4992-", - "A4993-", - "A4994-", - "T4995-", - "C4996-", - "T4997-", - "T4998-", - "G4999-", - "A5000-", - "A5001-", - "T5002-", - "C5003-", - "C5004-", - "T5005-", - "T5006-", - "T5007-", - "A5008-", - "G5009-", - "T5010-", - "G5011-", - "A5012-", - "T5013-", - "A5014-", - "C5015-", - "A5016-", - "C5017-", - "T5018-", - "G5019-", - "T5020-", - "G5021-", - "T5022-", - "C5023-", - "A5024-", - "A5025-", - "A5026-", - "A5027-", - "C5028-", - "T5029-", - "G5030-", - "G5031-", - "A5032-", - "T5033-", - "G5034-", - "T5035-", - "T5036-", - "T5037-", - "A5038-", - "G5039-", - "A5040-", - "A5041-", - "T5042-", - "A5043-", - "C5044-", - "C5045-", - "T5046-", - "A5047-", - "T5048-", - "G5049-", - "T5050-", - "A5051-", - "G5052-", - "A5053-", - "A5054-", - "T5055-", - "A5056-", - "T5057-", - "G5058-", - "G5059-", - "G5060-", - "A5061-", - "A5062-", - "G5063-", - "C5064-", - "A5065-", - "T5066-", - "G5067-", - "C5068-", - "T5069-", - "T5070-", - "G5071-", - "T5072-", - "T5073-", - "T5074-", - "T5075-", - "T5076-", - "G5077-", - "T5078-", - "C5079-", - "T5080-", - "C5081-", - "T5082-", - "A5083-", - "T5084-", - "T5085-", - "A5086-", - "T5087-", - "A5088-", - "G5089-", - "A5090-", - "T5091-", - "T5092-", - "A5093-", - "A5094-", - "C5095-", - "T5096-", - "C5097-", - "A5098-", - "T5099-", - "A5100-", - "C5101-", - "A5102-", - "T5103-", - "G5104-", - "G5105-", - "T5106-", - "T5107-", - "G5108-", - "T5109-", - "A5110-", - "T5111-", - "T5112-", - "A5113-", - "T5114-", - "G5115-", - "A5116-", - "A5117-", - "T5118-", - "T5119-", - "T5120-", - "T5121-", - "C5122-", - "A5123-", - "T5124-", - "C5125-", - "T5126-", - "G5127-", - "C5128-", - "C5129-", - "T5130-", - "A5131-", - "A5132-", - "T5133-", - "G5134-", - "T5135-", - "A5136-", - "C5137-", - "T5138-", - "C5139-", - "C5140-", - "A5141-", - "A5142-", - "T5143-", - "T5144-", - "C5145-", - "T5146-", - "T5147-", - "G5148-", - "T5149-", - "T5150-", - "T5151-", - "A5152-", - "C5153-", - "A5154-", - "A5155-", - "T5156-", - "C5157-", - "A5158-", - "A5159-", - "T5160-", - "T5161-", - "A5162-", - "T5163-", - "A5164-", - "T5165-", - "A5166-", - "A5167-", - "T5168-", - "C5169-", - "A5170-", - "A5171-", - "A5172-", - "G5173-", - "A5174-", - "G5175-", - "T5176-", - "G5177-", - "A5178-", - "T5179-", - "G5180-", - "A5181-", - "T5182-", - "G5183-", - "C5184-", - "A5185-", - "T5186-", - "A5187-", - "C5188-", - "A5189-", - "C5190-", - "A5191-", - "T5192-", - "T5193-", - "A5194-", - "C5195-", - "A5196-", - "A5197-", - "A5198-", - "G5199-", - "T5200-", - "G5201-", - "A5202-", - "A5203-", - "T5204-", - "A5205-", - "A5206-", - "T5207-", - "C5208-", - "T5209-", - "A5210-", - "C5211-", - "C5212-", - "A5213-", - "T5214-", - "C5215-", - "A5216-", - "T5217-", - "A5218-", - "A5219-", - "A5220-", - "A5221-", - "T5222-", - "A5223-", - "C5224-", - "T5225-", - "T5226-", - "G5227-", - "A5228-", - "T5229-", - "A5230-", - "C5231-", - "A5232-", - "G5233-", - "A5234-", - "G5235-", - "C5236-", - "T5237-", - "T5238-", - "T5239-", - "A5240-", - "T5241-", - "C5242-", - "A5243-", - "C5244-", - "A5245-", - "T5246-", - "C5247-", - "A5248-", - "T5249-", - "G5250-", - "G5251-", - "T5252-", - "T5253-", - "T5254-", - "T5255-", - "C5256-", - "A5257-", - "A5258-", - "T5259-", - "T5260-", - "G5261-", - "T5262-", - "A5263-", - "T5264-", - "T5265-", - "A5266-", - "T5267-", - "T5268-", - "A5269-", - "A5270-", - "G5271-", - "T5272-", - "A5273-", - "T5274-", - "A5275-", - "G5276-", - "C5277-", - "T5278-", - "A5279-", - "A5280-", - "T5281-", - "T5282-", - "T5283-", - "T5284-", - "A5285-", - "T5286-", - "A5287-", - "C5288-", - "A5289-", - "G5290-", - "T5291-", - "C5292-", - "A5293-", - "A5294-", - "T5295-", - "A5296-", - "G5297-", - "A5298-", - "C5299-", - "A5300-", - "A5301-", - "T5302-", - "G5303-", - "G5304-", - "T5305-", - "T5306-", - "C5307-", - "T5308-", - "C5309-", - "T5310-", - "A5311-", - "A5312-", - "G5313-", - "C5314-", - "A5315-", - "A5316-", - "T5317-", - "A5318-", - "T5319-", - "T5320-", - "T5321-", - "C5322-", - "T5323-", - "A5324-", - "A5325-", - "T5326-", - "A5327-", - "T5328-", - "T5329-", - "T5330-", - "T5331-", - "A5332-", - "A5333-", - "G5334-", - "A5335-", - "T5336-", - "G5337-", - "T5338-", - "G5339-", - "C5340-", - "T5341-", - "T5342-", - "C5343-", - "C5344-", - "C5345-", - "T5346-", - "A5347-", - "C5348-", - "G5349-", - "G5350-", - "G5351-", - "C5352-", - "G5353-", - "A5354-", - "T5355-", - "G5356-", - "A5357-", - "C5358-", - "A5359-", - "G5360-", - "A5361-", - "T5362-", - "C5363-", - "C5364-", - "C5365-", - "C5366-", - "T5367-", - "A5368-", - "T5369-", - "C5370-", - "C5371-", - "A5372-", - "C5373-", - "G5374-", - "G5375-", - "C5376-", - "C5377-", - "A5378-", - "C5379-", - "G5380-", - "T5381-", - "C5382-", - "A5383-", - "A5384-", - "G5385-", - "A5386-", - "C5387-", - "A5388-", - "T5389-", - "G5390-", - "T5391-", - "A5392-", - "T5393-", - "A5394-", - "T5395-", - "C5396-", - "C5397-", - "A5398-", - "T5399-", - "T5400-", - "A5401-", - "C5402-", - "T5403-", - "C5404-", - "A5405-", - "T5406-", - "T5407-", - "A5408-", - "C5409-", - "T5410-", - "G5411-", - "C5412-", - "G5413-", - "T5414-", - "T5415-", - "G5416-", - "A5417-", - "C5418-", - "A5419-", - "T5420-", - "T5421-", - "T5422-", - "G5423-", - "C5424-", - "T5425-", - "C5426-", - "C5427-", - "A5428-", - "T5429-", - "T5430-", - "T5431-", - "T5432-", - "C5433-", - "T5434-", - "A5435-", - "A5436-", - "T5437-", - "A5438-", - "G5439-", - "C5440-", - "C5441-", - "A5442-", - "T5443-", - "G5444-", - "A5445-", - "T5446-", - "A5447-", - "C5448-", - "T5449-", - "A5450-", - "A5451-", - "A5452-", - "T5453-", - "C5454-", - "T5455-", - "A5456-", - "T5457-", - "A5458-", - "T5459-", - "A5460-", - "A5461-", - "C5462-", - "C5463-", - "T5464-", - "G5465-", - "C5466-", - "A5467-", - "T5468-", - "A5469-", - "G5470-", - "A5471-", - "T5472-", - "A5473-", - "G5474-", - "C5475-", - "G5476-", - "C5477-", - "G5478-", - "A5479-", - "T5480-", - "A5481-", - "A5482-", - "A5483-", - "G5484-", - "C5485-", - "A5486-", - "A5487-", - "G5488-", - "G5489-", - "T5490-", - "C5491-", - "C5492-", - "T5493-", - "T5494-", - "C5495-", - "C5496-", - "A5497-", - "C5498-", - "C5499-", - "A5500-", - "G5501-", - "C5502-", - "A5503-", - "T5504-", - "C5505-", - "T5506-", - "A5507-", - "G5508-", - "T5509-", - "T5510-", - "G5511-", - "A5512-", - "T5513-", - "T5514-", - "G5515-", - "A5516-", - "T5517-", - "A5518-", - "T5519-", - "C5520-", - "T5521-", - "T5522-", - "C5523-", - "A5524-", - "A5525-", - "T5526-", - "A5527-", - "T5528-", - "A5529-", - "T5530-", - "G5531-", - "G5532-", - "G5533-", - "A5534-", - "T5535-", - "A5536-", - "C5537-", - "A5538-", - "A5539-", - "A5540-", - "G5541-", - "C5542-", - "T5543-", - "T5544-", - "A5545-", - "T5546-", - "A5547-", - "A5548-", - "A5549-", - "T5550-", - "T5551-", - "T5552-", - "C5553-", - "T5554-", - "A5555-", - "A5556-", - "T5557-", - "A5558-", - "C5559-", - "T5560-", - "G5561-", - "T5562-", - "G5563-", - "G5564-", - "G5565-", - "T5566-", - "T5567-", - "C5568-", - "A5569-", - "T5570-", - "C5571-", - "T5572-", - "A5573-", - "C5574-", - "A5575-", - "A5576-", - "G5577-", - "G5578-", - "A5579-", - "A5580-", - "T5581-", - "C5582-", - "C5583-", - "C5584-", - "C5585-", - "T5586-", - "A5587-", - "G5588-", - "T5589-", - "A5590-", - "T5591-", - "A5592-", - "C5593-", - "T5594-", - "G5595-", - "A5596-", - "A5597-", - "T5598-", - "T5599-", - "A5600-", - "T5601-", - "T5602-", - "T5603-", - "T5604-", - "A5605-", - "T5606-", - "A5607-", - "T5608-", - "A5609-", - "G5610-", - "A5611-", - "T5612-", - "C5613-", - "T5614-", - "A5615-", - "A5616-", - "T5617-", - "T5618-", - "T5619-", - "A5620-", - "A5621-", - "C5622-", - "A5623-", - "T5624-", - "C5625-", - "A5626-", - "T5627-", - "T5628-", - "T5629-", - "T5630-", - "C5631-", - "A5632-", - "T5633-", - "C5634-", - "T5635-", - "G5636-", - "G5637-", - "G5638-", - "A5639-", - "T5640-", - "A5641-", - "C5642-", - "C5643-", - "A5644-", - "C5645-", - "A5646-", - "A5647-", - "T5648-", - "T5649-", - "C5650-", - "A5651-", - "A5652-", - "A5653-", - "A5654-", - "T5655-", - "A5656-", - "A5657-", - "A5658-", - "C5659-", - "T5660-", - "C5661-", - "A5662-", - "A5663-", - "C5664-", - "A5665-", - "A5666-", - "C5667-", - "A5668-", - "C5669-", - "T5670-", - "A5671-", - "C5672-", - "T5673-", - "T5674-", - "T5675-", - "C5676-", - "C5677-", - "T5678-", - "T5679-", - "T5680-", - "T5681-", - "T5682-", - "A5683-", - "C5684-", - "A5685-", - "T5686-", - "A5687-", - "T5688-", - "T5689-", - "C5690-", - "C5691-", - "C5692-", - "C5693-", - "T5694-", - "A5695-", - "A5696-", - "A5697-", - "A5698-", - "T5699-", - "A5700-", - "G5701-", - "G5702-", - "C5703-", - "A5704-", - "T5705-", - "T5706-", - "C5707-", - "A5708-", - "A5709-", - "G5710-", - "C5711-", - "A5712-", - "T5713-", - "T5714-", - "C5715-", - "T5716-", - "A5717-", - "T5718-", - "T5719-", - "T5720-", - "T5721-", - "A5722-", - "T5723-", - "A5724-", - "T5725-", - "A5726-", - "T5727-", - "T5728-", - "A5729-", - "C5730-", - "A5731-", - "G5732-", - "C5733-", - "C5734-", - "C5735-", - "C5736-", - "A5737-", - "T5738-", - "G5739-", - "A5740-", - "T5741-", - "C5742-", - "T5743-", - "A5744-", - "C5745-", - "C5746-", - "A5747-", - "T5748-", - "A5749-", - "A5750-", - "G5751-", - "A5752-", - "T5753-", - "C5754-", - "A5755-", - "A5756-", - "C5757-", - "A5758-", - "A5759-", - "T5760-", - "G5761-", - "T5762-", - "C5763-", - "T5764-", - "A5765-", - "T5766-", - "T5767-", - "T5768-", - "C5769-", - "T5770-", - "A5771-", - "C5772-", - "A5773-", - "T5774-", - "A5775-", - "T5776-", - "G5777-", - "C5778-", - "A5779-", - "T5780-", - "T5781-", - "A5782-", - "G5783-", - "A5784-", - "T5785-", - "A5786-", - "G5787-", - "A5788-", - "T5789-", - "A5790-", - "G5791-", - "T5792-", - "A5793-", - "A5794-", - "A5795-", - "G5796-", - "T5797-", - "A5798-", - "A5799-", - "G5800-", - "A5801-", - "G5802-", - "A5803-", - "T5804-", - "C5805-", - "T5806-", - "T5807-", - "G5808-", - "C5809-", - "A5810-", - "C5811-", - "A5812-", - "G5813-", - "A5814-", - "A5815-", - "T5816-", - "T5817-", - "A5818-", - "C5819-", - "A5820-", - "A5821-", - "T5822-", - "T5823-", - "C5824-", - "T5825-", - "T5826-", - "A5827-", - "A5828-", - "T5829-", - "A5830-", - "A5831-", - "T5832-", - "T5833-", - "A5834-", - "T5835-", - "A5836-", - "G5837-", - "A5838-", - "G5839-", - "A5840-", - "A5841-", - "A5842-", - "A5843-", - "T5844-", - "A5845-", - "T5846-", - "C5847-", - "T5848-", - "T5849-", - "C5850-", - "C5851-", - "A5852-", - "T5853-", - "A5854-", - "T5855-", - "A5856-", - "A5857-", - "T5858-", - "T5859-", - "C5860-", - "T5861-", - "T5862-", - "T5863-", - "G5864-", - "A5865-", - "C5866-", - "A5867-", - "C5868-", - "T5869-", - "A5870-", - "A5871-", - "T5872-", - "G5873-", - "C5874-", - "A5875-", - "G5876-", - "A5877-", - "T5878-", - "A5879-", - "T5880-", - "A5881-", - "A5882-", - "T5883-", - "A5884-", - "T5885-", - "C5886-", - "T5887-", - "T5888-", - "T5889-", - "A5890-", - "T5891-", - "A5892-", - "T5893-", - "G5894-", - "T5895-", - "A5896-", - "A5897-", - "T5898-", - "A5899-", - "T5900-", - "A5901-", - "T5902-", - "G5903-", - "C5904-", - "A5905-", - "A5906-", - "A5907-", - "C5908-", - "A5909-", - "G5910-", - "T5911-", - "C5912-", - "T5913-", - "A5914-", - "T5915-", - "C5916-", - "T5917-", - "A5918-", - "C5919-", - "T5920-", - "A5921-", - "T5922-", - "A5923-", - "T5924-", - "A5925-", - "C5926-", - "T5927-", - "G5928-", - "A5929-", - "T5930-", - "C5931-", - "A5932-", - "A5933-", - "T5934-", - "A5935-", - "T5936-", - "T5937-", - "A5938-", - "T5939-", - "C5940-", - "T5941-", - "C5942-", - "T5943-", - "A5944-", - "T5945-", - "G5946-", - "A5947-", - "A5948-", - "T5949-", - "C5950-", - "C5951-", - "T5952-", - "A5953-", - "A5954-", - "A5955-", - "A5956-", - "T5957-", - "A5958-", - "A5959-", - "T5960-", - "C5961-", - "A5962-", - "T5963-", - "A5964-", - "C5965-", - "A5966-", - "G5967-", - "A5968-", - "A5969-", - "C5970-", - "A5971-", - "T5972-", - "C5973-", - "T5974-", - "A5975-", - "C5976-", - "A5977-", - "G5978-", - "G5979-", - "A5980-", - "T5981-", - "C5982-", - "A5983-", - "C5984-", - "A5985-", - "A5986-", - "A5987-", - "T5988-", - "T5989-", - "G5990-", - "G5991-", - "T5992-", - "T5993-", - "C5994-", - "A5995-", - "A5996-", - "G5997-", - "G5998-", - "A5999-", - "G6000-", - "A6001-", - "A6002-", - "A6003-", - "T6004-", - "C6005-", - "T6006-", - "A6007-", - "T6008-", - "C6009-", - "A6010-", - "A6011-", - "A6012-", - "T6013-", - "A6014-", - "T6015-", - "T6016-", - "T6017-", - "T6018-", - "C6019-", - "C6020-", - "T6021-", - "G6022-", - "T6023-", - "C6024-", - "A6025-", - "A6026-", - "C6027-", - "A6028-", - "A6029-", - "C6030-", - "T6031-", - "G6032-", - "G6033-", - "T6034-", - "T6035-", - "C6036-", - "T6037-", - "A6038-", - "G6039-", - "A6040-", - "A6041-", - "C6042-", - "A6043-", - "T6044-", - "A6045-", - "A6046-", - "C6047-", - "A6048-", - "G6049-", - "T6050-", - "C6051-", - "A6052-", - "A6053-", - "C6054-", - "A6055-", - "C6056-", - "C6057-", - "T6058-", - "A6059-", - "A6060-", - "T6061-", - "C6062-", - "C6063-", - "A6064-", - "T6065-", - "G6066-", - "T6067-", - "T6068-", - "T6069-", - "T6070-", - "T6071-", - "T6072-", - "A6073-", - "T6074-", - "A6075-", - "A6076-", - "T6077-", - "C6078-", - "A6079-", - "T6080-", - "C6081-", - "T6082-", - "A6083-", - "C6084-", - "C6085-", - "A6086-", - "A6087-", - "A6088-", - "G6089-", - "A6090-", - "T6091-", - "A6092-", - "A6093-", - "T6094-", - "G6095-", - "A6096-", - "C6097-", - "C6098-", - "A6099-", - "A6100-", - "A6101-", - "G6102-", - "A6103-", - "T6104-", - "C6105-", - "G6106-", - "A6107-", - "G6108-", - "G6109-", - "T6110-", - "C6111-", - "G6112-", - "T6113-", - "C6114-", - "G6115-", - "T6116-", - "G6117-", - "A6118-", - "A6119-", - "A6120-", - "C6121-", - "T6122-", - "G6123-", - "C6124-", - "T6125-", - "C6126-", - "A6127-", - "T6128-", - "C6129-", - "G6130-", - "A6131-", - "C6132-", - "A6133-", - "G6134-", - "C6135-", - "C6136-", - "A6137-", - "T6138-", - "G6139-", - "A6140-", - "A6141-", - "A6142-", - "T6143-", - "C6144-", - "T6145-", - "A6146-", - "C6147-", - "C6148-", - "G6149-", - "A6150-", - "C6151-", - "T6152-", - "C6153-", - "C6154-", - "A6155-", - "T6156-", - "G6157-", - "G6158-", - "T6159-", - "G6160-", - "C6161-", - "G6162-", - "A6163-", - "A6164-", - "T6165-", - "C6166-", - "G6167-", - "C6168-", - "A6169-", - "C6170-", - "T6171-", - "G6172-", - "T6173-", - "C6174-", - "T6175-", - "T6176-", - "A6177-", - "T6178-", - "T6179-", - "C6180-", - "G6181-", - "C6182-", - "C6183-", - "A6184-", - "T6185-", - "T6186-", - "G6187-", - "A6188-", - "T6189-", - "T6190-", - "T6191-", - "T6192-", - "C6193-", - "A6194-", - "T6195-", - "T6196-", - "T6197-", - "T6198-", - "T6199-", - "T6200-", - "A6201-", - "T6202-", - "A6203-", - "A6204-", - "T6205-", - "T6206-", - "A6207-", - "T6208-", - "G6209-", - "T6210-", - "A6211-", - "C6212-", - "A6213-", - "T6214-", - "G6215-", - "T6216-", - "T6217-", - "T6218-", - "T6219-", - "C6220-", - "C6221-", - "T6222-", - "T6223-", - "C6224-", - "T6225-", - "A6226-", - "T6227-", - "T6228-", - "C6229-", - "T6230-", - "C6231-", - "A6232-", - "A6233-", - "G6234-", - "A6235-", - "G6236-", - "T6237-", - "C6238-", - "T6239-", - "A6240-", - "C6241-", - "A6242-", - "A6243-", - "A6244-", - "A6245-", - "A6246-", - "T6247-", - "A6248-", - "T6249-", - "A6250-", - "T6251-", - "T6252-", - "T6253-", - "T6254-", - "T6255-", - "T6256-", - "C6257-", - "G6258-", - "A6259-", - "T6260-", - "A6261-", - "T6262-", - "C6263-", - "T6264-", - "A6265-", - "A6266-", - "G6267-", - "T6268-", - "A6269-", - "C6270-", - "T6271-", - "A6272-", - "A6273-", - "G6274-", - "T6275-", - "T6276-", - "T6277-", - "T6278-", - "T6279-", - "T6280-", - "T6281-", - "A6282-", - "C6283-", - "T6284-", - "G6285-", - "T6286-", - "T6287-", - "T6288-", - "T6289-", - "T6290-", - "G6291-", - "T6292-", - "T6293-", - "A6294-", - "C6295-", - "T6296-", - "G6297-", - "T6298-", - "C6299-", - "T6300-", - "T6301-", - "C6302-", - "C6303-", - "A6304-", - "T6305-", - "T6306-", - "C6307-", - "T6308-", - "T6309-", - "C6310-", - "T6311-", - "A6312-", - "A6313-", - "C6314-", - "T6315-", - "A6316-", - "A6317-", - "A6318-", - "G6319-", - "A6320-", - "T6321-", - "C6322-", - "T6323-", - "G6324-", - "A6325-", - "G6326-", - "A6327-", - "T6328-", - "A6329-", - "A6330-", - "A6331-", - "T6332-", - "T6333-", - "A6334-", - "T6335-", - "A6336-", - "C6337-", - "A6338-", - "A6339-", - "T6340-", - "C6341-", - "T6342-", - "T6343-", - "C6344-", - "G6345-", - "C6346-", - "T6347-", - "A6348-", - "T6349-", - "C6350-", - "G6351-", - "A6352-", - "A6353-", - "C6354-", - "C6355-", - "A6356-", - "T6357-", - "T6358-", - "T6359-", - "T6360-", - "T6361-", - "G6362-", - "T6363-", - "A6364-", - "G6365-", - "T6366-", - "C6367-", - "T6368-", - "A6369-", - "A6370-", - "A6371-", - "G6372-", - "C6373-", - "C6374-", - "T6375-", - "G6376-", - "A6377-", - "A6378-", - "G6379-", - "T6380-", - "A6381-", - "A6382-", - "T6383-", - "T6384-", - "A6385-", - "A6386-", - "C6387-", - "C6388-", - "A6389-", - "A6390-", - "C6391-", - "T6392-", - "G6393-", - "T6394-", - "T6395-", - "T6396-", - "T6397-", - "T6398-", - "A6399-", - "T6400-", - "T6401-", - "A6402-", - "G6403-", - "T6404-", - "G6405-", - "G6406-", - "C6407-", - "T6408-", - "T6409-", - "T6410-", - "T6411-", - "T6412-", - "T6413-", - "C6414-", - "G6415-", - "A6416-", - "T6417-", - "C6418-", - "T6419-", - "A6420-", - "T6421-", - "C6422-", - "C6423-", - "T6424-", - "C6425-", - "G6426-", - "T6427-", - "C6428-", - "C6429-", - "T6430-", - "C6431-", - "T6432-", - "C6433-", - "A6434-", - "T6435-", - "C6436-", - "A6437-", - "T6438-", - "C6439-", - "C6440-", - "T6441-", - "T6442-", - "A6443-", - "T6444-", - "A6445-", - "T6446-", - "T6447-", - "A6448-", - "T6449-", - "T6450-", - "A6451-", - "T6452-", - "C6453-", - "A6454-", - "T6455-", - "T6456-", - "A6457-", - "T6458-", - "T6459-", - "A6460-", - "T6461-", - "C6462-", - "A6463-", - "T6464-", - "A6465-", - "G6466-", - "T6467-", - "C6468-", - "T6469-", - "A6470-", - "T6471-", - "T6472-", - "A6473-", - "A6474-", - "A6475-", - "C6476-", - "A6477-", - "C6478-", - "A6479-", - "A6480-", - "A6481-", - "T6482-", - "C6483-", - "A6484-", - "T6485-", - "C6486-", - "T6487-", - "A6488-", - "C6489-", - "G6490-", - "T6491-", - "T6492-", - "T6493-", - "A6494-", - "T6495-", - "A6496-", - "A6497-", - "C6498-", - "A6499-", - "A6500-", - "C6501-", - "A6502-", - "T6503-", - "T6504-", - "C6505-", - "T6506-", - "C6507-", - "A6508-", - "T6509-", - "T6510-", - "A6511-", - "T6512-", - "T6513-", - "A6514-", - "A6515-", - "T6516-", - "T6517-", - "A6518-", - "G6519-", - "T6520-", - "T6521-", - "C6522-", - "T6523-", - "G6524-", - "T6525-", - "A6526-", - "G6527-", - "A6528-", - "A6529-", - "T6530-", - "A6531-", - "T6532-", - "C6533-", - "T6534-", - "T6535-", - "T6536-", - "A6537-", - "A6538-", - "T6539-", - "A6540-", - "A6541-", - "T6542-", - "T6543-", - "T6544-", - "G6545-", - "G6546-", - "C6547-", - "T6548-", - "A6549-", - "T6550-", - "A6551-", - "C6552-", - "A6553-", - "T6554-", - "C6555-", - "T6556-", - "G6557-", - "T6558-", - "T6559-", - "C6560-", - "A6561-", - "A6562-", - "T6563-", - "A6564-", - "C6565-", - "T6566-", - "A6567-", - "T6568-", - "C6569-", - "T6570-", - "A6571-", - "T6572-", - "T6573-", - "G6574-", - "A6575-", - "T6576-", - "G6577-", - "A6578-", - "T6579-", - "T6580-", - "T6581-", - "C6582-", - "T6583-", - "T6584-", - "T6585-", - "T6586-", - "T6587-", - "T6588-", - "A6589-", - "A6590-", - "G6591-", - "A6592-", - "C6593-", - "T6594-", - "T6595-", - "A6596-", - "A6597-", - "A6598-", - "C6599-", - "T6600-", - "A6601-", - "G6602-", - "T6603-", - "T6604-", - "A6605-", - "T6606-", - "G6607-", - "G6608-", - "T6609-", - "A6610-", - "A6611-", - "T6612-", - "G6613-", - "A6614-", - "C6615-", - "G6616-", - "A6617-", - "T6618-", - "G6619-", - "A6620-", - "A6621-", - "A6622-", - "T6623-", - "C6624-", - "G6625-", - "A6626-", - "G6627-", - "T6628-", - "A6629-", - "G6630-", - "T6631-", - "A6632-", - "A6633-", - "C6634-", - "T6635-", - "T6636-", - "C6637-", - "T6638-", - "A6639-", - "A6640-", - "T6641-", - "A6642-", - "A6643-", - "A6644-", - "G6645-", - "A6646-", - "C6647-", - "T6648-", - "T6649-", - "G6650-", - "A6651-", - "T6652-", - "A6653-", - "T6654-", - "C6655-", - "A6656-", - "T6657-", - "T6658-", - "A6659-", - "T6660-", - "C6661-", - "A6662-", - "T6663-", - "A6664-", - "T6665-", - "G6666-", - "T6667-", - "T6668-", - "T6669-", - "G6670-", - "A6671-", - "T6672-", - "C6673-", - "G6674-", - "T6675-", - "C6676-", - "A6677-", - "T6678-", - "A6679-", - "G6680-", - "T6681-", - "T6682-", - "A6683-", - "A6684-", - "T6685-", - "A6686-", - "G6687-", - "T6688-", - "G6689-", - "T6690-", - "G6691-", - "G6692-", - "C6693-", - "T6694-", - "A6695-", - "A6696-", - "A6697-", - "T6698-", - "G6699-", - "G6700-", - "T6701-", - "A6702-", - "C6703-", - "T6704-", - "G6705-", - "T6706-", - "T6707-", - "A6708-", - "A6709-", - "T6710-", - "A6711-", - "A6712-", - "G6713-", - "T6714-", - "T6715-", - "T6716-", - "A6717-", - "T6718-", - "A6719-", - "G6720-", - "A6721-", - "C6722-", - "A6723-", - "A6724-", - "T6725-", - "A6726-", - "T6727-", - "C6728-", - "A6729-", - "T6730-", - "A6731-", - "G6732-", - "T6733-", - "A6734-", - "T6735-", - "T6736-", - "T6737-", - "T6738-", - "C6739-", - "T6740-", - "T6741-", - "T6742-", - "C6743-", - "C6744-", - "A6745-", - "G6746-", - "A6747-", - "A6748-", - "T6749-", - "T6750-", - "A6751-", - "G6752-", - "A6753-", - "T6754-", - "T6755-", - "A6756-", - "T6757-", - "T6758-", - "T6759-", - "T6760-", - "T6761-", - "T6762-", - "T6763-", - "A6764-", - "A6765-", - "A6766-", - "T6767-", - "A6768-", - "C6769-", - "T6770-", - "G6771-", - "A6772-", - "T6773-", - "C6774-", - "C6775-", - "T6776-", - "C6777-", - "A6778-", - "C6779-", - "A6780-", - "A6781-", - "T6782-", - "T6783-", - "C6784-", - "C6785-", - "G6786-", - "T6787-", - "G6788-", - "A6789-", - "T6790-", - "G6791-", - "T6792-", - "A6793-", - "G6794-", - "C6795-", - "A6796-", - "G6797-", - "T6798-", - "A6799-", - "G6800-", - "T6801-", - "T6802-", - "G6803-", - "G6804-", - "T6805-", - "G6806-", - "C6807-", - "A6808-", - "T6809-", - "G6810-", - "G6811-", - "T6812-", - "C6813-", - "T6814-", - "A6815-", - "T6816-", - "A6817-", - "T6818-", - "C6819-", - "G6820-", - "T6821-", - "T6822-", - "A6823-", - "A6824-", - "A6825-", - "A6826-", - "T6827-", - "G6828-", - "T6829-", - "A6830-", - "T6831-", - "C6832-", - "A6833-", - "T6834-", - "A6835-", - "T6836-", - "A6837-", - "T6838-", - "A6839-", - "A6840-", - "T6841-", - "A6842-", - "G6843-", - "T6844-", - "T6845-", - "T6846-", - "T6847-", - "C6848-", - "T6849-", - "G6850-", - "A6851-", - "C6852-", - "G6853-", - "T6854-", - "G6855-", - "G6856-", - "A6857-", - "G6858-", - "T6859-", - "A6860-", - "C6861-", - "A6862-", - "G6863-", - "A6864-", - "A6865-", - "T6866-", - "T6867-", - "T6868-", - "T6869-", - "C6870-", - "G6871-", - "A6872-", - "T6873-", - "T6874-", - "A6875-", - "A6876-", - "T6877-", - "G6878-", - "A6879-", - "G6880-", - "T6881-", - "T6882-", - "C6883-", - "A6884-", - "T6885-", - "G6886-", - "G6887-", - "T6888-", - "A6889-", - "A6890-", - "G6891-", - "G6892-", - "A6893-", - "A6894-", - "G6895-", - "G6896-", - "G6897-", - "C6898-", - "A6899-", - "A6900-", - "A6901-", - "T6902-", - "G6903-", - "C6904-", - "C6905-", - "T6906-", - "G6907-", - "T6908-", - "A6909-", - "T6910-", - "A6911-", - "T6912-", - "A6913-", - "A6914-", - "T6915-", - "A6916-", - "T6917-", - "A6918-", - "C6919-", - "A6920-", - "T6921-", - "A6922-", - "A6923-", - "G6924-", - "T6925-", - "T6926-", - "A6927-", - "A6928-", - "T6929-", - "A6930-", - "G6931-", - "T6932-", - "T6933-", - "T6934-", - "T6935-", - "T6936-", - "T6937-", - "A6938-", - "T6939-", - "C6940-", - "A6941-", - "T6942-", - "A6943-", - "T6944-", - "T6945-", - "T6946-", - "T6947-", - "C6948-", - "T6949-", - "A6950-", - "A6951-", - "T6952-", - "A6953-", - "C6954-", - "C6955-", - "A6956-", - "T6957-", - "A6958-", - "A6959-", - "T6960-", - "A6961-", - "A6962-", - "A6963-", - "A6964-", - "A6965-", - "T6966-", - "T6967-", - "A6968-", - "T6969-", - "C6970-", - "A6971-", - "T6972-", - "T6973-", - "A6974-", - "T6975-", - "G6976-", - "C6977-", - "G6978-", - "T6979-", - "T6980-", - "T6981-", - "G6982-", - "G6984-", - "T6985-", - "A6986-", - "G6987-", - "T6988-", - "T6989-", - "C6990-", - "T6991-", - "G6992-", - "C6993-", - "C6994-", - "C6995-", - "T6996-", - "A6997-", - "T6998-", - "C6999-", - "A7000-", - "T7001-", - "C7002-", - "T7003-", - "A7004-", - "T7005-", - "A7006-", - "T7007-", - "C7008-", - "A7009-", - "C7010-", - "T7011-", - "G7012-", - "T7013-", - "C7014-", - "A7015-", - "C7016-", - "T7017-", - "C7018-", - "T7019-", - "C7020-", - "G7021-", - "C7022-", - "T7023-", - "C7024-", - "T7025-", - "C7026-", - "A7027-", - "C7028-", - "T7029-", - "A7030-", - "T7031-", - "A7032-", - "T7033-", - "C7034-", - "T7035-", - "T7036-", - "C7037-", - "T7038-", - "A7039-", - "A7040-", - "A7041-", - "A7042-", - "T7043-", - "T7044-", - "A7045-", - "C7046-", - "A7047-", - "A7048-", - "A7049-", - "C7050-", - "A7051-", - "A7052-", - "C7053-", - "T7054-", - "G7055-", - "G7056-", - "A7057-", - "T7058-", - "A7059-", - "T7060-", - "T7061-", - "C7062-", - "G7063-", - "A7064-", - "T7065-", - "A7066-", - "A7067-", - "C7068-", - "A7069-", - "G7070-", - "C7071-", - "A7072-", - "T7073-", - "T7074-", - "T7075-", - "G7076-", - "T7077-", - "G7078-", - "T7079-", - "A7080-", - "G7081-", - "T7082-", - "T7083-", - "T7084-", - "T7085-", - "T7086-", - "G7087-", - "T7088-", - "C7089-", - "T7090-", - "T7091-", - "T7092-", - "T7093-", - "A7094-", - "C7095-", - "A7096-", - "G7097-", - "T7098-", - "A7099-", - "T7100-", - "A7101-", - "T7102-", - "A7103-", - "C7104-", - "G7105-", - "T7106-", - "T7107-", - "A7108-", - "T7109-", - "T7110-", - "G7111-", - "T7112-", - "C7113-", - "A7114-", - "A7115-", - "A7116-", - "A7117-", - "T7118-", - "C7119-", - "T7120-", - "A7121-", - "A7122-", - "A7123-", - "C7124-", - "A7125-", - "A7126-", - "A7127-", - "T7128-", - "A7129-", - "T7130-", - "T7131-", - "A7132-", - "G7133-", - "C7134-", - "A7135-", - "T7136-", - "A7137-", - "A7138-", - "T7139-", - "A7140-", - "C7141-", - "A7142-", - "T7143-", - "C7144-", - "T7145-", - "A7146-", - "T7147-", - "C7148-", - "T7149-", - "A7150-", - "T7151-", - "A7152-", - "A7153-", - "G7154-", - "A7155-", - "T7156-", - "C7157-", - "A7158-", - "G7159-", - "G7160-", - "A7161-", - "T7162-", - "C7163-", - "C7164-", - "A7165-", - "T7166-", - "G7167-", - "T7168-", - "T7169-", - "C7170-", - "G7171-", - "A7172-", - "G7173-", - "C7174-", - "A7175-", - "T7176-", - "A7177-", - "C7178-", - "T7179-", - "A7180-", - "G7181-", - "C7182-", - "C7183-", - "A7184-", - "T7185-", - "G7186-", - "T7187-", - "A7188-", - "T7189-", - "A7190-", - "T7191-", - "T7192-", - "T7193-", - "G7194-", - "T7195-", - "A7196-", - "A7197-", - "C7198-", - "T7199-", - "T7200-", - "C7201-", - "G7202-", - "T7203-", - "C7204-", - "G7205-", - "T7206-", - "A7207-", - "C7208-", - "A7209-", - "G7210-", - "C7211-", - "G7212-", - "T7213-", - "T7214-", - "A7215-", - "G7216-", - "A7217-", - "T7218-", - "C7219-", - "A7220-", - "A7221-", - "T7222-", - "A7223-", - "G7224-", - "A7225-", - "A7226-", - "T7227-", - "A7228-", - "A7229-", - "A7230-", - "C7231-", - "A7232-", - "A7233-", - "T7234-", - "C7235-", - "G7236-", - "T7237-", - "G7238-", - "T7239-", - "G7240-", - "A7241-", - "C7242-", - "G7243-", - "C7244-", - "A7245-", - "A7246-", - "C7247-", - "T7248-", - "T7249-", - "T7250-", - "T7251-", - "T7252-", - "T7253-", - "A7254-", - "C7255-", - "G7256-", - "A7257-", - "T7258-", - "C7259-", - "T7260-", - "A7261-", - "G7262-", - "T7263-", - "T7264-", - "G7265-", - "T7266-", - "A7267-", - "T7268-", - "G7269-", - "A7270-", - "G7271-", - "T7272-", - "T7273-", - "T7274-", - "A7275-", - "T7276-", - "C7277-", - "G7278-", - "T7279-", - "T7280-", - "T7281-", - "A7282-", - "C7283-", - "A7284-", - "T7285-", - "A7286-", - "A7287-", - "G7288-", - "C7289-", - "A7290-", - "A7291-", - "T7292-", - "T7293-", - "A7294-", - "A7295-", - "C7296-", - "G7297-", - "G7298-", - "C7299-", - "T7300-", - "T7301-", - "T7302-", - "A7303-", - "A7304-", - "C7305-", - "A7306-", - "G7307-", - "A7308-", - "T7309-", - "G7310-", - "A7311-", - "T7312-", - "C7313-", - "T7314-", - "G7315-", - "A7316-", - "G7317-", - "T7318-", - "A7319-", - "A7320-", - "T7321-", - "A7322-", - "A7323-", - "T7324-", - "A7325-", - "T7326-", - "A7327-", - "C7328-", - "C7329-", - "T7330-", - "C7331-", - "T7332-", - "G7333-", - "T7334-", - "T7335-", - "A7336-", - "T7337-", - "A7338-", - "C7339-", - "G7340-", - "T7341-", - "T7342-", - "T7343-", - "A7344-", - "A7345-", - "T7346-", - "G7347-", - "T7348-", - "T7349-", - "C7350-", - "A7351-", - "C7352-", - "G7353-", - "G7354-", - "T7355-", - "C7356-", - "T7357-", - "T7358-", - "A7359-", - "G7360-", - "T7361-", - "A7362-", - "T7363-", - "T7364-", - "T7365-", - "T7366-", - "T7367-", - "A7368-", - "G7369-", - "A7370-", - "T7371-", - "A7372-", - "T7373-", - "C7374-", - "A7375-", - "A7376-", - "T7377-", - "T7378-", - "G7379-", - "T7380-", - "G7381-", - "A7382-", - "T7383-", - "T7384-", - "T7385-", - "A7386-", - "C7387-", - "A7388-", - "C7389-", - "C7390-", - "A7391-", - "T7392-", - "A7393-", - "T7394-", - "T7395-", - "C7396-", - "G7397-", - "A7398-", - "C7399-", - "T7400-", - "C7401-", - "C7402-", - "C7403-", - "T7404-", - "T7405-", - "G7406-", - "T7407-", - "G7408-", - "T7409-", - "G7410-", - "T7411-", - "A7412-", - "A7413-", - "C7414-", - "G7415-", - "T7416-", - "T7417-", - "A7418-", - "G7419-", - "A7420-", - "A7421-", - "A7422-", - "T7423-", - "T7424-", - "C7425-", - "T7426-", - "A7427-", - "A7428-", - "A7429-", - "T7430-", - "C7431-", - "T7432-", - "A7433-", - "T7434-", - "A7435-", - "T7436-", - "T7437-", - "A7438-", - "T7439-", - "C7440-", - "T7441-", - "A7442-", - "T7443-", - "T7444-", - "A7445-", - "C7446-", - "A7447-", - "G7448-", - "C7449-", - "G7450-", - "T7451-", - "A7452-", - "A7453-", - "A7454-", - "A7455-", - "C7456-", - "A7457-", - "C7458-", - "A7459-", - "T7460-", - "T7461-", - "C7462-", - "A7463-", - "A7464-", - "T7465-", - "A7466-", - "T7467-", - "T7468-", - "G7469-", - "T7470-", - "A7471-", - "T7472-", - "T7473-", - "G7474-", - "T7475-", - "T7476-", - "A7477-", - "T7478-", - "T7479-", - "T7480-", - "T7481-", - "T7482-", - "A7483-", - "T7484-", - "A7485-", - "T7486-", - "T7487-", - "A7488-", - "T7489-", - "T7490-", - "T7491-", - "A7492-", - "C7493-", - "A7494-", - "C7495-", - "A7496-", - "A7497-", - "T7498-", - "T7499-", - "A7500-", - "A7501-", - "C7502-", - "A7503-", - "A7504-", - "T7505-", - "G7506-", - "T7507-", - "A7508-", - "T7509-", - "T7510-", - "A7511-", - "T7512-", - "T7513-", - "A7514-", - "G7515-", - "T7516-", - "T7517-", - "T7518-", - "A7519-", - "T7520-", - "A7521-", - "T7522-", - "T7523-", - "A7524-", - "C7525-", - "T7526-", - "G7527-", - "A7528-", - "A7529-", - "T7530-", - "T7531-", - "A7532-", - "A7533-", - "T7534-", - "A7535-", - "A7536-", - "T7537-", - "A7538-", - "T7539-", - "A7540-", - "A7541-", - "A7542-", - "A7543-", - "T7544-", - "T7545-", - "C7546-", - "C7547-", - "C7548-", - "A7549-", - "A7550-", - "T7551-", - "C7552-", - "T7553-", - "T7554-", - "G7555-", - "T7556-", - "C7557-", - "A7558-", - "T7559-", - "A7560-", - "A7561-", - "A7562-", - "C7563-", - "A7564-", - "C7565-", - "A7566-", - "A7567-", - "A7568-", - "A7569-", - "T7570-", - "C7571-", - "C7572-", - "A7573-", - "T7574-", - "T7575-", - "A7576-", - "A7577-", - "A7578-", - "A7579-", - "A7580-", - "T7581-", - "G7582-", - "T7583-", - "C7584-", - "G7585-", - "A7586-", - "T7587-", - "A7588-", - "A7589-", - "A7590-", - "A7591-", - "T7592-", - "A7593-", - "T7594-", - "C7595-", - "T7596-", - "G7597-", - "A7598-", - "T7599-", - "G7600-", - "T7601-", - "T7602-", - "G7603-", - "T7604-", - "T7605-", - "G7606-", - "T7607-", - "T7608-", - "C7609-", - "G7610-", - "C7611-", - "T7612-", - "G7613-", - "C7614-", - "T7615-", - "A7616-", - "T7617-", - "G7618-", - "A7619-", - "T7620-", - "A7621-", - "A7622-", - "T7623-", - "C7624-", - "A7625-", - "G7626-", - "A7627-", - "T7628-", - "C7629-", - "A7630-", - "T7631-", - "T7632-", - "A7633-", - "G7634-", - "C7635-", - "C7636-", - "G7637-", - "A7638-", - "T7639-", - "A7640-", - "G7641-", - "T7642-", - "G7643-", - "G7644-", - "T7645-", - "A7646-", - "A7647-", - "T7648-", - "G7649-", - "C7650-", - "T7651-", - "A7652-", - "T7653-", - "C7654-", - "G7655-", - "A7656-", - "A7657-", - "A7658-", - "C7659-", - "A7660-", - "A7661-", - "C7662-", - "A7663-", - "T7664-", - "C7665-", - "G7666-", - "C7667-", - "C7668-", - "A7669-", - "G7670-", - "A7671-", - "A7672-", - "A7673-", - "T7674-", - "T7675-", - "A7676-", - "C7677-", - "A7678-", - "A7679-", - "A7680-", - "C7681-", - "G7682-", - "C7683-", - "T7684-", - "A7685-", - "C7686-", - "A7687-", - "A7688-", - "C7689-", - "A7690-", - "G7691-", - "A7692-", - "T7693-", - "A7694-", - "T7695-", - "T7696-", - "C7697-", - "C7698-", - "A7699-", - "G7700-", - "C7701-", - "T7702-", - "A7703-", - "T7704-", - "C7705-", - "A7706-", - "G7707-", - "A7708-", - "T7709-", - "T7710-", - "A7711-", - "T7712-", - "G7713-", - "T7714-", - "G7715-", - "G7716-", - "T7717-", - "C7718-", - "C7719-", - "A7720-", - "G7721-", - "A7722-", - "G7723-", - "G7724-", - "G7725-", - "A7726-", - "G7727-", - "A7728-", - "T7729-", - "G7730-", - "G7731-", - "A7732-", - "T7733-", - "A7734-", - "T7735-", - "T7736-", - "G7737-", - "T7738-", - "T7739-", - "T7740-", - "A7741-", - "C7742-", - "A7743-", - "C7744-", - "G7745-", - "G7746-", - "T7747-", - "G7748-", - "A7749-", - "C7750-", - "T7751-", - "G7752-", - "T7753-", - "A7754-", - "T7755-", - "C7756-", - "C7757-", - "A7758-", - "C7759-", - "G7760-", - "C7761-", - "T7762-", - "A7763-", - "G7764-", - "A7765-", - "G7766-", - "A7767-", - "T7768-", - "A7769-", - "T7770-", - "C7771-", - "G7772-", - "A7773-", - "C7774-", - "G7775-", - "G7776-", - "T7777-", - "A7778-", - "T7779-", - "G7780-", - "T7781-", - "A7782-", - "T7783-", - "T7784-", - "G7785-", - "T7786-", - "A7787-", - "G7788-", - "A7789-", - "T7790-", - "G7791-", - "C7792-", - "T7793-", - "C7794-", - "T7795-", - "C7796-", - "A7797-", - "T7798-", - "G7799-", - "G7800-", - "T7801-", - "T7802-", - "A7803-", - "T7804-", - "A7805-", - "C7806-", - "A7807-", - "G7808-", - "G7809-", - "T7810-", - "A7811-", - "T7812-", - "T7813-", - "A7814-", - "G7815-", - "A7816-", - "T7817-", - "G7818-", - "T7819-", - "C7820-", - "A7821-", - "G7822-", - "C7823-", - "A7824-", - "T7825-", - "G7826-", - "T7827-", - "A7828-", - "G7829-", - "T7830-", - "A7831-", - "T7832-", - "T7833-", - "A7834-", - "G7835-", - "T7836-", - "A7837-", - "G7838-", - "A7839-", - "C7840-", - "T7841-", - "A7842-", - "T7843-", - "C7844-", - "A7845-", - "A7846-", - "C7847-", - "G7848-", - "T7849-", - "T7850-", - "C7851-", - "A7852-", - "G7853-", - "G7854-", - "A7855-", - "A7856-", - "A7857-", - "A7858-", - "C7859-", - "C7860-", - "A7861-", - "G7862-", - "A7863-", - "C7864-", - "A7865-", - "C7866-", - "T7867-", - "A7868-", - "C7869-", - "A7870-", - "A7871-", - "C7872-", - "A7873-", - "T7874-", - "C7875-", - "A7876-", - "T7877-", - "A7878-", - "T7879-", - "A7880-", - "T7881-", - "C7882-", - "C7883-", - "C7884-", - "A7885-", - "T7886-", - "C7887-", - "T7888-", - "C7889-", - "T7890-", - "A7891-", - "G7892-", - "G7893-", - "T7894-", - "A7895-", - "T7896-", - "T7897-", - "G7898-", - "T7899-", - "G7900-", - "C7901-", - "T7902-", - "T7903-", - "G7904-", - "T7905-", - "A7906-", - "T7907-", - "T7908-", - "A7909-", - "G7910-", - "T7911-", - "A7912-", - "G7913-", - "G7914-", - "C7915-", - "A7916-", - "T7917-", - "T7918-", - "A7919-", - "T7920-", - "T7921-", - "A7922-", - "T7923-", - "T7924-", - "A7925-", - "C7926-", - "G7927-", - "T7928-", - "G7929-", - "T7930-", - "T7931-", - "G7932-", - "T7933-", - "C7934-", - "T7935-", - "A7936-", - "T7937-", - "T7938-", - "A7939-", - "T7940-", - "C7941-", - "T7942-", - "G7943-", - "T7944-", - "T7945-", - "T7946-", - "A7947-", - "T7948-", - "A7949-", - "T7950-", - "G7951-", - "T7952-", - "T7953-", - "C7954-", - "A7955-", - "C7956-", - "T7957-", - "C7958-", - "G7959-", - "A7960-", - "A7961-", - "G7962-", - "A7963-", - "A7964-", - "C7965-", - "T7966-", - "A7967-", - "A7968-", - "A7969-", - "C7970-", - "T7971-", - "A7972-", - "C7973-", - "C7974-", - "T7975-", - "A7976-", - "T7977-", - "A7978-", - "C7979-", - "A7980-", - "A7981-", - "G7982-", - "A7983-", - "T7984-", - "A7985-", - "T7986-", - "G7987-", - "G7988-", - "T7989-", - "T7990-", - "G7991-", - "T7992-", - "G7993-", - "T7994-", - "T7995-", - "A7996-", - "T7997-", - "A7998-", - "T7999-", - "T8000-", - "T8001-", - "T8002-", - "T8003-", - "T8004-", - "A8005-", - "T8006-", - "A8007-", - "A8008-", - "A8009-", - "A8010-", - "T8011-", - "T8012-", - "T8013-", - "T8014-", - "T8015-", - "T8016-", - "T8017-", - "A8018-", - "T8019-", - "G8020-", - "A8021-", - "G8022-", - "T8023-", - "A8024-", - "T8025-", - "T8026-", - "T8027-", - "T8028-", - "T8029-", - "A8030-", - "C8031-", - "A8032-", - "A8033-", - "A8034-", - "A8035-", - "A8036-", - "T8037-", - "G8038-", - "T8039-", - "A8040-", - "T8041-", - "A8042-", - "T8043-", - "G8044-", - "T8045-", - "A8046-", - "T8047-", - "A8048-", - "A8049-", - "A8050-", - "A8051-", - "A8052-", - "A8053-", - "A8054-", - "A8055-", - "T8056-", - "A8057-", - "C8058-", - "T8059-", - "A8060-", - "A8061-", - "G8062-", - "T8063-", - "A8064-", - "T8065-", - "A8066-", - "C8067-", - "G8068-", - "A8069-", - "T8070-", - "G8071-", - "T8072-", - "A8073-", - "T8074-", - "C8075-", - "C8076-", - "T8077-", - "G8078-", - "T8079-", - "A8080-", - "T8081-", - "T8082-", - "A8083-", - "T8084-", - "T8085-", - "T8086-", - "G8087-", - "T8088-", - "A8089-", - "T8090-", - "T8091-", - "T8092-", - "A8093-", - "T8094-", - "C8095-", - "T8096-", - "A8097-", - "A8098-", - "A8099-", - "C8100-", - "A8101-", - "A8102-", - "T8103-", - "A8104-", - "C8105-", - "T8106-", - "T8107-", - "C8108-", - "T8109-", - "G8110-", - "C8111-", - "C8112-", - "T8113-", - "C8114-", - "T8115-", - "A8116-", - "G8117-", - "A8118-", - "T8119-", - "G8120-", - "G8121-", - "G8122-", - "A8123-", - "T8124-", - "A8125-", - "C8126-", - "A8127-", - "A8128-", - "A8129-", - "A8130-", - "A8131-", - "T8132-", - "T8133-", - "T8134-", - "T8135-", - "T8136-", - "T8137-", - "A8138-", - "T8139-", - "T8140-", - "T8141-", - "C8142-", - "A8143-", - "G8144-", - "C8145-", - "A8146-", - "T8147-", - "A8148-", - "T8149-", - "T8150-", - "A8151-", - "A8152-", - "A8153-", - "G8154-", - "T8155-", - "A8156-", - "A8157-", - "A8158-", - "A8159-", - "T8160-", - "C8161-", - "T8162-", - "A8163-", - "G8164-", - "T8165-", - "T8166-", - "A8167-", - "C8168-", - "C8169-", - "T8170-", - "T8171-", - "G8172-", - "A8173-", - "A8174-", - "A8175-", - "A8176-", - "T8177-", - "G8178-", - "A8179-", - "A8180-", - "T8181-", - "A8182-", - "C8183-", - "A8184-", - "G8185-", - "T8186-", - "G8187-", - "G8188-", - "G8189-", - "T8190-", - "G8191-", - "G8192-", - "T8193-", - "T8194-", - "C8195-", - "C8196-", - "G8197-", - "T8198-", - "A8199-", - "T8200-", - "C8201-", - "A8202-", - "C8203-", - "C8204-", - "A8205-", - "G8206-", - "T8207-", - "A8208-", - "A8209-", - "G8210-", - "A8211-", - "A8212-", - "C8213-", - "A8214-", - "T8215-", - "A8216-", - "A8217-", - "T8218-", - "A8219-", - "G8220-", - "T8221-", - "C8222-", - "G8223-", - "A8224-", - "A8225-", - "T8226-", - "A8227-", - "C8228-", - "A8229-", - "G8230-", - "T8231-", - "A8232-", - "T8233-", - "C8234-", - "C8235-", - "G8236-", - "A8237-", - "T8238-", - "T8239-", - "G8240-", - "A8241-", - "G8242-", - "A8243-", - "T8244-", - "T8245-", - "T8246-", - "T8247-", - "G8248-", - "C8249-", - "A8250-", - "T8251-", - "A8252-", - "C8253-", - "A8254-", - "A8255-", - "T8256-", - "A8257-", - "C8258-", - "T8259-", - "A8260-", - "G8261-", - "T8262-", - "C8263-", - "T8264-", - "A8265-", - "G8266-", - "A8267-", - "A8268-", - "A8269-", - "G8270-", - "A8271-", - "A8272-", - "A8273-", - "T8274-", - "T8275-", - "T8276-", - "G8277-", - "T8278-", - "A8279-", - "A8280-", - "T8281-", - "C8282-", - "A8283-", - "T8284-", - "C8285-", - "C8286-", - "T8287-", - "C8288-", - "T8289-", - "G8290-", - "T8291-", - "G8292-", - "A8293-", - "C8294-", - "A8295-", - "G8296-", - "G8297-", - "A8298-", - "G8299-", - "T8300-", - "C8301-", - "C8302-", - "A8303-", - "T8304-", - "A8305-", - "T8306-", - "A8307-", - "T8308-", - "C8309-", - "T8310-", - "G8311-", - "T8312-", - "A8313-", - "T8314-", - "C8315-", - "A8316-", - "T8317-", - "C8318-", - "G8319-", - "T8320-", - "C8321-", - "T8322-", - "A8323-", - "G8324-", - "T8325-", - "T8326-", - "T8327-", - "T8328-", - "T8329-", - "A8330-", - "T8331-", - "C8332-", - "A8333-", - "G8334-", - "T8335-", - "G8336-", - "T8337-", - "C8338-", - "C8339-", - "T8340-", - "A8341-", - "T8342-", - "G8343-", - "C8344-", - "T8345-", - "A8346-", - "T8347-", - "A8348-", - "T8349-", - "T8350-", - "C8351-", - "C8352-", - "T8353-", - "G8354-", - "T8355-", - "T8356-", - "A8357-", - "T8358-", - "C8359-", - "A8360-", - "T8361-", - "C8362-", - "A8363-", - "T8364-", - "T8365-", - "A8366-", - "G8367-", - "T8368-", - "T8369-", - "A8370-", - "A8371-", - "T8372-", - "G8373-", - "A8374-", - "A8375-", - "A8376-", - "A8377-", - "T8378-", - "A8379-", - "A8380-", - "C8381-", - "T8382-", - "C8383-", - "T8384-", - "C8385-", - "G8386-", - "T8387-", - "G8388-", - "C8389-", - "T8390-", - "T8391-", - "C8392-", - "A8393-", - "G8394-", - "A8395-", - "A8396-", - "A8397-", - "A8398-", - "G8399-", - "T8400-", - "C8401-", - "A8402-", - "A8403-", - "A8404-", - "T8405-", - "A8406-", - "T8407-", - "T8408-", - "G8409-", - "T8410-", - "A8411-", - "T8412-", - "C8413-", - "C8414-", - "A8415-", - "T8416-", - "A8417-", - "C8418-", - "A8419-", - "T8420-", - "A8421-", - "T8422-", - "A8423-", - "T8424-", - "C8425-", - "T8426-", - "C8427-", - "C8428-", - "A8429-", - "A8430-", - "A8431-", - "A8432-", - "C8433-", - "T8434-", - "A8435-", - "T8436-", - "C8437-", - "A8438-", - "C8439-", - "T8440-", - "T8441-", - "A8442-", - "T8443-", - "A8444-", - "C8445-", - "G8446-", - "T8447-", - "T8448-", - "T8449-", - "A8450-", - "T8451-", - "C8452-", - "T8453-", - "T8454-", - "T8455-", - "A8456-", - "A8457-", - "C8458-", - "G8459-", - "A8460-", - "A8461-", - "C8462-", - "A8463-", - "T8464-", - "A8465-", - "T8466-", - "A8467-", - "C8468-", - "C8469-", - "T8470-", - "A8471-", - "G8472-", - "A8473-", - "T8474-", - "G8475-", - "G8476-", - "T8477-", - "T8478-", - "A8479-", - "T8480-", - "T8481-", - "T8482-", - "A8483-", - "C8484-", - "T8485-", - "A8486-", - "A8487-", - "C8488-", - "A8489-", - "G8490-", - "A8491-", - "C8492-", - "A8493-", - "T8494-", - "T8495-", - "T8496-", - "T8497-", - "T8498-", - "T8499-", - "C8500-", - "A8501-", - "A8502-", - "G8503-", - "A8504-", - "T8505-", - "C8506-", - "T8507-", - "A8508-", - "T8509-", - "T8510-", - "G8511-", - "A8512-", - "C8513-", - "A8514-", - "A8515-", - "T8516-", - "A8517-", - "A8518-", - "C8519-", - "T8520-", - "C8521-", - "C8522-", - "T8523-", - "A8524-", - "T8525-", - "A8526-", - "G8527-", - "T8528-", - "T8529-", - "T8530-", - "C8531-", - "C8532-", - "A8533-", - "C8534-", - "A8535-", - "T8536-", - "C8537-", - "A8538-", - "A8539-", - "C8540-", - "C8541-", - "A8542-", - "A8543-", - "G8544-", - "T8545-", - "A8546-", - "A8547-", - "T8548-", - "G8549-", - "A8550-", - "T8551-", - "C8552-", - "A8553-", - "T8554-", - "C8555-", - "T8556-", - "A8557-", - "T8558-", - "T8559-", - "G8560-", - "T8561-", - "T8562-", - "A8563-", - "T8564-", - "A8565-", - "T8566-", - "A8567-", - "A8568-", - "C8569-", - "A8570-", - "A8571-", - "T8572-", - "A8573-", - "A8574-", - "C8575-", - "A8576-", - "T8577-", - "A8578-", - "A8579-", - "C8580-", - "T8581-", - "C8582-", - "T8583-", - "T8584-", - "T8585-", - "T8586-", - "C8587-", - "C8588-", - "A8589-", - "T8590-", - "T8591-", - "T8592-", - "T8593-", - "T8594-", - "A8595-", - "T8596-", - "C8597-", - "A8598-", - "G8599-", - "T8600-", - "A8601-", - "T8602-", - "C8603-", - "T8604-", - "A8605-", - "T8606-", - "A8607-", - "T8608-", - "C8609-", - "A8610-", - "A8611-", - "C8612-", - "G8613-", - "T8614-", - "C8615-", - "G8616-", - "T8617-", - "T8618-", - "G8619-", - "T8620-", - "A8621-", - "G8622-", - "T8623-", - "G8624-", - "A8625-", - "A8626-", - "T8627-", - "A8628-", - "G8629-", - "T8630-", - "A8631-", - "G8632-", - "T8633-", - "C8634-", - "A8635-", - "T8636-", - "T8637-", - "G8638-", - "A8639-", - "T8640-", - "C8641-", - "T8642-", - "A8643-", - "T8644-", - "T8645-", - "A8646-", - "T8647-", - "A8648-", - "T8649-", - "G8650-", - "A8651-", - "A8652-", - "A8653-", - "C8654-", - "G8655-", - "G8656-", - "A8657-", - "T8658-", - "A8659-", - "T8660-", - "G8661-", - "T8662-", - "C8663-", - "T8664-", - "A8665-", - "G8666-", - "T8667-", - "T8668-", - "A8669-", - "A8670-", - "T8671-", - "A8672-", - "T8673-", - "T8674-", - "T8675-", - "T8676-", - "C8677-", - "T8678-", - "T8679-", - "T8680-", - "G8681-", - "A8682-", - "T8683-", - "T8684-", - "T8685-", - "A8686-", - "A8687-", - "A8688-", - "G8689-", - "T8690-", - "C8691-", - "T8692-", - "A8693-", - "T8694-", - "A8695-", - "G8696-", - "T8697-", - "C8698-", - "T8699-", - "T8700-", - "T8701-", - "A8702-", - "C8703-", - "A8704-", - "A8705-", - "A8706-", - "C8707-", - "A8708-", - "T8709-", - "A8710-", - "A8711-", - "T8712-", - "A8713-", - "T8714-", - "C8715-", - "C8716-", - "T8717-", - "T8718-", - "A8719-", - "T8720-", - "C8721-", - "C8722-", - "G8723-", - "A8724-", - "C8725-", - "T8726-", - "T8727-", - "T8728-", - "A8729-", - "T8730-", - "A8731-", - "T8732-", - "T8733-", - "T8734-", - "C8735-", - "C8736-", - "T8737-", - "G8738-", - "T8739-", - "A8740-", - "G8741-", - "G8742-", - "G8743-", - "T8744-", - "G8745-", - "G8746-", - "C8747-", - "A8748-", - "T8749-", - "A8750-", - "A8751-", - "T8752-", - "T8753-", - "T8754-", - "T8755-", - "A8756-", - "T8757-", - "T8758-", - "C8759-", - "T8760-", - "G8761-", - "C8762-", - "C8763-", - "T8764-", - "C8765-", - "C8766-", - "A8767-", - "C8768-", - "A8769-", - "A8770-", - "T8771-", - "C8772-", - "A8773-", - "G8774-", - "T8775-", - "G8776-", - "T8777-", - "T8778-", - "T8779-", - "C8780-", - "C8781-", - "A8782-", - "A8783-", - "A8784-", - "T8785-", - "A8786-", - "T8787-", - "A8788-", - "T8789-", - "T8790-", - "A8791-", - "C8792-", - "T8793-", - "A8794-", - "G8795-", - "A8796-", - "C8797-", - "A8798-", - "A8799-", - "T8800-", - "A8801-", - "T8802-", - "T8803-", - "C8804-", - "C8805-", - "A8806-", - "T8807-", - "A8808-", - "T8809-", - "A8810-", - "G8811-", - "T8812-", - "T8813-", - "A8814-", - "T8815-", - "T8816-", - "A8817-", - "G8818-", - "T8819-", - "T8820-", - "A8821-", - "A8822-", - "G8823-", - "G8824-", - "G8825-", - "A8826-", - "C8827-", - "C8828-", - "C8829-", - "A8830-", - "A8831-", - "T8832-", - "T8833-", - "A8834-", - "G8835-", - "A8836-", - "A8837-", - "C8838-", - "A8839-", - "C8840-", - "G8841-", - "T8842-", - "A8843-", - "C8844-", - "G8845-", - "C8846-", - "G8847-", - "C8848-", - "T8849-", - "T8850-", - "A8851-", - "T8852-", - "T8853-", - "C8854-", - "A8855-", - "T8856-", - "C8857-", - "A8858-", - "T8859-", - "T8860-", - "T8861-", - "G8862-", - "G8863-", - "A8864-", - "T8865-", - "C8866-", - "G8867-", - "T8868-", - "A8869-", - "T8870-", - "T8871-", - "T8872-", - "C8873-", - "A8874-", - "T8875-", - "A8876-", - "A8877-", - "A8878-", - "A8879-", - "G8880-", - "T8881-", - "T8882-", - "A8883-", - "T8884-", - "T8885-", - "A8886-", - "T8887-", - "G8888-", - "T8889-", - "T8890-", - "A8891-", - "T8892-", - "A8893-", - "G8894-", - "A8895-", - "T8896-", - "G8897-", - "T8898-", - "C8899-", - "A8900-", - "A8901-", - "C8902-", - "A8903-", - "C8904-", - "A8905-", - "T8906-", - "T8907-", - "C8908-", - "T8909-", - "A8910-", - "C8911-", - "A8912-", - "T8913-", - "T8914-", - "T8915-", - "T8916-", - "T8917-", - "T8918-", - "T8919-", - "A8920-", - "A8921-", - "T8922-", - "T8923-", - "G8924-", - "T8925-", - "C8926-", - "T8927-", - "A8928-", - "T8929-", - "A8930-", - "T8931-", - "A8932-", - "G8933-", - "T8934-", - "A8935-", - "T8936-", - "T8937-", - "T8938-", - "T8939-", - "T8940-", - "C8941-", - "T8942-", - "G8943-", - "A8944-", - "T8945-", - "A8946-", - "T8947-", - "T8948-", - "T8949-", - "T8950-", - "C8951-", - "T8952-", - "A8953-", - "T8954-", - "A8955-", - "A8956-", - "T8957-", - "A8958-", - "T8959-", - "C8960-", - "A8961-", - "G8962-", - "A8963-", - "A8964-", - "T8965-", - "T8966-", - "G8967-", - "T8968-", - "C8969-", - "T8970-", - "T8971-", - "C8972-", - "C8973-", - "A8974-", - "T8975-", - "A8976-", - "G8977-", - "G8978-", - "A8979-", - "A8980-", - "G8981-", - "T8982-", - "T8983-", - "G8984-", - "T8985-", - "A8986-", - "T8987-", - "A8988-", - "C8989-", - "T8990-", - "A8991-", - "T8992-", - "T8993-", - "C8994-", - "G8995-", - "G8996-", - "A8997-", - "A8998-", - "T8999-", - "C9000-", - "A9001-", - "G9002-", - "T9003-", - "T9004-", - "A9005-", - "C9006-", - "A9007-", - "T9008-", - "G9009-", - "T9010-", - "T9011-", - "T9012-", - "A9013-", - "A9014-", - "A9015-", - "T9016-", - "A9017-", - "A9018-", - "T9019-", - "T9020-", - "C9021-", - "T9022-", - "C9023-", - "T9024-", - "G9025-", - "A9026-", - "T9027-", - "G9028-", - "T9029-", - "C9030-", - "A9031-", - "T9032-", - "T9033-", - "C9034-", - "C9035-", - "T9036-", - "T9037-", - "A9038-", - "T9039-", - "A9040-", - "C9041-", - "A9042-", - "A9043-", - "T9044-", - "C9045-", - "A9046-", - "A9047-", - "A9048-", - "T9049-", - "T9050-", - "C9051-", - "A9052-", - "T9053-", - "T9054-", - "A9055-", - "T9056-", - "T9057-", - "A9058-", - "A9059-", - "A9060-", - "C9061-", - "A9062-", - "G9063-", - "T9064-", - "T9065-", - "T9066-", - "A9067-", - "A9068-", - "T9069-", - "A9070-", - "G9071-", - "T9072-", - "C9073-", - "T9074-", - "G9075-", - "T9076-", - "A9077-", - "G9078-", - "A9079-", - "C9080-", - "C9081-", - "T9082-", - "T9083-", - "T9084-", - "A9085-", - "T9086-", - "C9087-", - "G9088-", - "T9089-", - "C9090-", - "G9091-", - "T9092-", - "A9093-", - "C9094-", - "A9095-", - "T9096-", - "A9097-", - "T9098-", - "C9099-", - "C9100-", - "A9101-", - "T9102-", - "T9103-", - "G9104-", - "T9105-", - "C9106-", - "T9107-", - "T9108-", - "A9109-", - "T9110-", - "T9111-", - "A9112-", - "G9113-", - "T9114-", - "T9115-", - "A9116-", - "C9117-", - "G9118-", - "C9119-", - "T9120-", - "T9121-", - "A9122-", - "T9123-", - "T9124-", - "T9125-", - "T9126-", - "T9127-", - "A9128-", - "T9129-", - "G9130-", - "G9131-", - "G9132-", - "T9133-", - "T9134-", - "T9135-", - "T9136-", - "A9137-", - "C9138-", - "G9139-", - "T9140-", - "T9141-", - "G9142-", - "C9143-", - "T9144-", - "T9145-", - "T9146-", - "A9147-", - "T9148-", - "T9149-", - "A9150-", - "T9151-", - "A9152-", - "T9153-", - "T9154-", - "T9155-", - "T9156-", - "A9157-", - "T9158-", - "A9159-", - "A9160-", - "T9161-", - "A9162-", - "A9163-", - "T9164-", - "G9165-", - "A9166-", - "T9167-", - "T9168-", - "G9169-", - "T9170-", - "T9171-", - "T9172-", - "G9173-", - "A9174-", - "C9175-", - "A9176-", - "A9177-", - "T9178-", - "G9179-", - "T9180-", - "C9181-", - "G9182-", - "T9183-", - "A9184-", - "G9185-", - "T9186-", - "A9187-", - "T9188-", - "A9189-", - "G9190-", - "A9191-", - "T9192-", - "A9193-", - "T9194-", - "A9195-", - "T9196-", - "T9197-", - "A9198-", - "T9199-", - "T9200-", - "A9201-", - "G9202-", - "A9203-", - "G9204-", - "G9205-", - "A9206-", - "G9207-", - "G9208-", - "T9209-", - "A9210-", - "T9211-", - "A9212-", - "A9213-", - "T9214-", - "T9215-", - "A9216-", - "T9217-", - "A9218-", - "A9219-", - "A9220-", - "A9221-", - "A9222-", - "G9223-", - "T9224-", - "T9225-", - "T9226-", - "C9227-", - "T9228-", - "G9229-", - "A9230-", - "G9231-", - "T9232-", - "A9233-", - "C9234-", - "G9235-", - "A9236-", - "T9237-", - "G9238-", - "T9239-", - "T9240-", - "A9241-", - "T9242-", - "A9243-", - "A9244-", - "G9245-", - "A9246-", - "G9247-", - "G9248-", - "A9249-", - "G9250-", - "A9251-", - "G9252-", - "G9253-", - "A9254-", - "C9255-", - "A9256-", - "C9257-", - "A9258-", - "T9259-", - "T9260-", - "A9261-", - "A9262-", - "C9263-", - "A9264-", - "T9265-", - "C9266-", - "A9267-", - "T9268-", - "A9269-", - "C9270-", - "A9271-", - "T9272-", - "C9273-", - "A9274-", - "A9275-", - "T9276-", - "T9277-", - "A9278-", - "A9279-", - "C9280-", - "T9281-", - "A9282-", - "C9283-", - "A9284-", - "T9285-", - "T9286-", - "C9287-", - "T9288-", - "T9289-", - "A9290-", - "T9291-", - "A9292-", - "A9293-", - "C9294-", - "A9295-", - "T9296-", - "T9297-", - "G9298-", - "T9299-", - "A9300-", - "A9301-", - "T9302-", - "C9303-", - "A9304-", - "A9305-", - "A9306-", - "A9307-", - "G9308-", - "A9309-", - "A9310-", - "T9311-", - "T9312-", - "G9313-", - "C9314-", - "A9315-", - "A9316-", - "T9317-", - "T9318-", - "T9319-", - "T9320-", - "G9321-", - "A9322-", - "T9323-", - "G9324-", - "T9325-", - "A9326-", - "T9327-", - "A9328-", - "A9329-", - "C9330-", - "A9331-", - "A9332-", - "C9333-", - "T9334-", - "G9335-", - "T9336-", - "C9337-", - "A9338-", - "A9339-", - "T9340-", - "G9341-", - "G9342-", - "A9343-", - "A9344-", - "T9345-", - "T9346-", - "G9347-", - "T9348-", - "A9349-", - "T9350-", - "A9351-", - "T9352-", - "T9353-", - "A9354-", - "C9355-", - "A9356-", - "A9357-", - "A9358-", - "T9359-", - "T9360-", - "A9361-", - "C9362-", - "G9363-", - "G9364-", - "T9365-", - "A9366-", - "T9367-", - "G9368-", - "T9369-", - "T9370-", - "G9371-", - "T9372-", - "A9373-", - "A9374-", - "C9375-", - "A9376-", - "A9377-", - "C9378-", - "A9379-", - "A9380-", - "A9381-", - "T9382-", - "A9383-", - "C9384-", - "C9385-", - "G9386-", - "A9387-", - "T9388-", - "C9389-", - "G9390-", - "G9391-", - "T9392-", - "A9393-", - "A9394-", - "T9395-", - "T9396-", - "G9397-", - "T9398-", - "C9399-", - "T9400-", - "C9401-", - "T9402-", - "G9403-", - "C9404-", - "C9405-", - "G9406-", - "C9407-", - "T9408-", - "G9409-", - "T9410-", - "A9411-", - "A9412-", - "T9413-", - "A9414-", - "G9415-", - "A9416-", - "A9417-", - "T9418-", - "T9419-", - "A9420-", - "A9421-", - "T9422-", - "T9423-", - "A9424-", - "T9425-", - "A9426-", - "T9427-", - "A9428-", - "T9429-", - "C9430-", - "T9431-", - "A9432-", - "T9433-", - "T9434-", - "A9435-", - "C9436-", - "A9437-", - "C9438-", - "C9439-", - "G9440-", - "G9441-", - "C9442-", - "C9443-", - "T9444-", - "T9445-", - "G9446-", - "T9447-", - "A9448-", - "T9449-", - "C9450-", - "A9451-", - "T9452-", - "A9453-", - "A9454-", - "T9455-", - "A9456-", - "A9457-", - "A9458-", - "G9459-", - "T9460-", - "T9461-", - "G9462-", - "T9463-", - "G9464-", - "G9465-", - "T9466-", - "A9467-", - "G9468-", - "T9469-", - "A9470-", - "T9471-", - "G9472-", - "A9473-", - "T9474-", - "C9475-", - "T9476-", - "C9477-", - "C9478-", - "A9479-", - "T9480-", - "A9481-", - "T9482-", - "T9483-", - "T9484-", - "A9485-", - "T9486-", - "A9487-", - "A9488-", - "T9489-", - "T9490-", - "T9491-", - "A9492-", - "G9493-", - "T9494-", - "A9495-", - "C9496-", - "T9497-", - "T9498-", - "T9499-", - "G9500-", - "T9501-", - "A9502-", - "T9503-", - "T9504-", - "T9505-", - "A9506-", - "G9507-", - "T9508-", - "T9509-", - "T9510-", - "T9511-", - "T9512-", - "T9513-", - "T9514-", - "G9515-", - "G9516-", - "A9517-", - "A9518-", - "T9519-", - "C9520-", - "A9521-", - "T9522-", - "A9523-", - "A9524-", - "A9525-", - "A9526-", - "A9527-", - "A9528-", - "A9529-", - "G9530-", - "T9531-", - "T9532-", - "T9533-", - "T9534-", - "A9535-", - "C9536-", - "T9537-", - "A9538-", - "A9539-", - "T9540-", - "T9541-", - "T9542-", - "A9543-", - "A9544-", - "A9545-", - "A9546-", - "T9547-", - "T9548-", - "T9549-", - "A9550-", - "A9551-", - "A9552-", - "A9553-", - "A9554-", - "G9555-", - "T9556-", - "A9557-", - "T9558-", - "T9559-", - "T9560-", - "A9561-", - "C9562-", - "A9563-", - "T9564-", - "T9565-", - "T9566-", - "T9567-", - "T9568-", - "C9569-", - "A9570-", - "C9571-", - "T9572-", - "G9573-", - "T9574-", - "T9575-", - "T9576-", - "A9577-", - "G9578-", - "T9579-", - "C9580-", - "G9581-", - "C9582-", - "G9583-", - "G9584-", - "A9585-", - "T9586-", - "A9587-", - "T9588-", - "G9589-", - "G9590-", - "A9591-", - "A9592-", - "T9593-", - "T9594-", - "C9595-", - "G9596-", - "A9597-", - "T9598-", - "C9599-", - "C9600-", - "T9601-", - "G9602-", - "T9603-", - "C9604-", - "A9605-", - "A9606-", - "A9607-", - "A9608-", - "T9609-", - "C9610-", - "A9611-", - "A9612-", - "T9613-", - "A9614-", - "C9615-", - "A9616-", - "T9617-", - "C9618-", - "A9619-", - "T9620-", - "C9621-", - "T9622-", - "A9623-", - "T9624-", - "A9625-", - "G9626-", - "A9627-", - "T9628-", - "C9629-", - "A9630-", - "T9631-", - "G9632-", - "T9633-", - "A9634-", - "A9635-", - "C9636-", - "A9637-", - "A9638-", - "T9639-", - "A9640-", - "T9641-", - "T9642-", - "A9643-", - "C9644-", - "A9645-", - "A9646-", - "T9647-", - "A9648-", - "C9649-", - "A9650-", - "T9651-", - "A9652-", - "G9653-", - "A9654-", - "T9655-", - "G9656-", - "A9657-", - "A9658-", - "C9659-", - "C9660-", - "A9661-", - "A9662-", - "A9663-", - "T9664-", - "G9665-", - "A9666-", - "T9667-", - "A9668-", - "T9669-", - "A9670-", - "A9671-", - "G9672-", - "A9673-", - "C9674-", - "T9675-", - "A9676-", - "A9677-", - "C9678-", - "A9679-", - "G9680-", - "T9681-", - "A9682-", - "T9683-", - "G9684-", - "C9685-", - "A9686-", - "T9687-", - "T9688-", - "A9689-", - "T9690-", - "C9691-", - "C9692-", - "G9693-", - "A9694-", - "A9695-", - "A9696-", - "T9697-", - "G9698-", - "T9699-", - "T9700-", - "A9701-", - "A9702-", - "T9703-", - "A9704-", - "A9705-", - "C9706-", - "A9707-", - "T9708-", - "T9709-", - "A9710-", - "C9711-", - "A9712-", - "T9713-", - "A9714-", - "T9715-", - "T9716-", - "A9717-", - "T9718-", - "A9719-", - "T9720-", - "C9721-", - "A9722-", - "A9723-", - "T9724-", - "A9725-", - "T9726-", - "C9727-", - "A9728-", - "C9729-", - "A9730-", - "A9731-", - "A9732-", - "A9733-", - "A9734-", - "T9735-", - "A9736-", - "A9737-", - "A9738-", - "T9739-", - "C9740-", - "C9741-", - "A9742-", - "C9743-", - "A9744-", - "T9745-", - "T9746-", - "T9747-", - "G9748-", - "G9749-", - "C9750-", - "T9751-", - "A9752-", - "A9753-", - "T9754-", - "C9755-", - "G9756-", - "A9757-", - "T9758-", - "T9759-", - "T9760-", - "C9761-", - "G9762-", - "G9763-", - "G9764-", - "C9765-", - "T9766-", - "T9767-", - "G9768-", - "G9769-", - "A9770-", - "A9771-", - "A9772-", - "A9773-", - "A9774-", - "A9775-", - "C9776-", - "G9777-", - "T9778-", - "A9779-", - "T9780-", - "C9781-", - "G9782-", - "C9783-", - "C9784-", - "G9785-", - "G9786-", - "A9787-", - "A9788-", - "G9789-", - "G9790-", - "G9791-", - "A9792-", - "C9793-", - "T9794-", - "A9795-", - "T9796-", - "A9797-", - "T9798-", - "G9799-", - "A9800-", - "C9801-", - "T9802-", - "A9803-", - "A9804-", - "C9805-", - "T9806-", - "T9807-", - "A9808-", - "T9809-", - "C9810-", - "T9811-", - "A9812-", - "G9813-", - "A9814-", - "G9815-", - "A9816-", - "T9817-", - "A9818-", - "C9819-", - "A9820-", - "G9821-", - "G9822-", - "A9823-", - "A9824-", - "T9825-", - "A9826-", - "C9827-", - "A9828-", - "A9829-", - "C9830-", - "A9831-", - "A9832-", - "T9833-", - "C9834-", - "A9835-", - "A9836-", - "A9837-", - "A9838-", - "C9839-", - "T9840-", - "T9841-", - "A9842-", - "C9843-", - "T9844-", - "G9845-", - "A9846-", - "A9847-", - "A9848-", - "C9849-", - "T9850-", - "A9851-", - "T9852-", - "A9853-", - "C9854-", - "G9855-", - "T9856-", - "A9857-", - "A9858-", - "C9859-", - "T9860-", - "G9861-", - "T9862-", - "C9863-", - "A9864-", - "A9865-", - "A9866-", - "A9867-", - "A9868-", - "A9869-", - "A9870-", - "T9871-", - "A9872-", - "A9873-", - "A9874-", - "A9875-", - "A9876-", - "C9877-", - "A9878-", - "T9879-", - "A9880-", - "T9881-", - "A9882-", - "T9883-", - "G9884-", - "G9885-", - "T9886-", - "C9887-", - "T9888-", - "A9889-", - "T9890-", - "A9891-", - "T9892-", - "A9893-", - "T9894-", - "A9895-", - "C9896-", - "A9897-", - "C9898-", - "T9899-", - "A9900-", - "C9901-", - "A9902-", - "A9903-", - "T9904-", - "T9905-", - "T9906-", - "A9907-", - "G9908-", - "T9909-", - "T9910-", - "A9911-", - "T9912-", - "T9913-", - "A9914-", - "A9915-", - "T9916-", - "G9917-", - "T9918-", - "G9919-", - "G9920-", - "T9921-", - "T9922-", - "A9923-", - "T9924-", - "T9925-", - "G9926-", - "A9927-", - "T9928-", - "T9929-", - "G9930-", - "G9931-", - "A9932-", - "T9933-", - "A9934-", - "A9935-", - "C9936-", - "C9937-", - "G9938-", - "A9939-", - "T9940-", - "G9941-", - "T9942-", - "G9943-", - "A9944-", - "T9945-", - "T9946-", - "G9947-", - "T9948-", - "T9949-", - "C9950-", - "A9951-", - "A9952-", - "T9953-", - "C9954-", - "A9955-", - "A9956-", - "T9957-", - "A9958-", - "T9959-", - "T9960-", - "A9961-", - "A9962-", - "G9963-", - "A9964-", - "G9965-", - "G9966-", - "G9967-", - "T9968-", - "T9969-", - "G9970-", - "G9971-", - "T9972-", - "A9973-", - "A9974-", - "A9975-", - "T9976-", - "T9977-", - "G9978-", - "G9979-", - "T9980-", - "A9981-", - "C9982-", - "A9983-", - "T9984-", - "A9985-", - "G9986-", - "C9987-", - "T9988-", - "A9989-", - "A9990-", - "T9991-", - "A9992-", - "A9993-", - "T9994-", - "A9995-", - "C9996-", - "A9997-", - "T9998-", - "A9999-", - "T10000-", - "A10001-", - "C10002-", - "T10003-", - "C10004-", - "C10005-", - "A10006-", - "A10007-", - "A10008-", - "T10009-", - "A10010-", - "C10011-", - "A10012-", - "C10013-", - "C10014-", - "C10015-", - "A10016-", - "A10017-", - "T10018-", - "A10019-", - "A10020-", - "T10021-", - "A10022-", - "C10023-", - "T10024-", - "A10025-", - "C10026-", - "A10027-", - "A10028-", - "C10029-", - "C10030-", - "A10031-", - "T10032-", - "T10033-", - "T10034-", - "C10035-", - "T10036-", - "G10037-", - "A10038-", - "G10039-", - "T10040-", - "T10041-", - "G10042-", - "G10043-", - "A10044-", - "T10045-", - "A10046-", - "T10047-", - "C10048-", - "A10049-", - "T10050-", - "C10051-", - "A10052-", - "A10053-", - "A10054-", - "A10055-", - "T10056-", - "A10057-", - "C10058-", - "T10059-", - "G10060-", - "G10061-", - "A10062-", - "T10063-", - "A10064-", - "A10065-", - "A10066-", - "T10067-", - "A10068-", - "C10069-", - "G10070-", - "A10071-", - "G10072-", - "G10073-", - "A10074-", - "C10075-", - "A10076-", - "T10077-", - "G10078-", - "T10079-", - "A10080-", - "T10081-", - "A10082-", - "G10083-", - "A10084-", - "G10085-", - "T10086-", - "A10087-", - "A10088-", - "G10089-", - "T10090-", - "A10091-", - "A10092-", - "A10093-", - "G10094-", - "A10095-", - "A10096-", - "A10097-", - "A10098-", - "A10099-", - "G10100-", - "A10101-", - "A10102-", - "T10103-", - "G10104-", - "T10105-", - "G10106-", - "G10107-", - "A10108-", - "A10109-", - "T10110-", - "T10111-", - "T10112-", - "G10113-", - "C10114-", - "T10115-", - "A10116-", - "T10117-", - "G10118-", - "A10119-", - "A10120-", - "G10121-", - "T10122-", - "T10123-", - "G10124-", - "T10125-", - "T10126-", - "T10127-", - "A10128-", - "C10129-", - "T10130-", - "C10131-", - "A10132-", - "A10133-", - "A10134-", - "A10135-", - "C10136-", - "G10137-", - "A10138-", - "T10139-", - "T10140-", - "A10141-", - "G10142-", - "A10143-", - "A10144-", - "A10145-", - "A10146-", - "C10147-", - "G10148-", - "A10149-", - "T10150-", - "A10151-", - "G10152-", - "A10153-", - "T10154-", - "A10155-", - "C10156-", - "T10157-", - "T10158-", - "T10159-", - "G10160-", - "G10161-", - "T10162-", - "T10163-", - "T10164-", - "A10165-", - "T10166-", - "T10167-", - "G10168-", - "G10169-", - "A10170-", - "T10171-", - "T10172-", - "C10173-", - "G10174-", - "T10175-", - "G10176-", - "T10177-", - "A10178-", - "A10179-", - "T10180-", - "C10181-", - "A10182-", - "T10183-", - "A10184-", - "T10185-", - "A10186-", - "T10187-", - "T10188-", - "T10189-", - "T10190-", - "G10191-", - "C10192-", - "A10193-", - "T10194-", - "A10195-", - "A10196-", - "C10197-", - "A10198-", - "T10199-", - "G10200-", - "T10201-", - "A10202-", - "T10203-", - "C10204-", - "A10205-", - "A10206-", - "T10207-", - "A10208-", - "T10209-", - "A10210-", - "T10211-", - "G10212-", - "G10213-", - "C10214-", - "A10215-", - "T10216-", - "A10217-", - "G10218-", - "A10219-", - "A10220-", - "C10221-", - "A10222-", - "C10223-", - "G10224-", - "A10225-", - "A10226-", - "G10227-", - "A10228-", - "G10229-", - "A10230-", - "A10231-", - "A10232-", - "C10233-", - "C10234-", - "G10235-", - "G10236-", - "T10237-", - "G10238-", - "C10239-", - "G10240-", - "T10241-", - "C10242-", - "A10243-", - "G10244-", - "A10245-", - "T10246-", - "A10247-", - "A10248-", - "T10249-", - "T10250-", - "G10251-", - "T10252-", - "C10253-", - "C10254-", - "T10255-", - "A10256-", - "T10257-", - "A10258-", - "T10259-", - "G10260-", - "C10261-", - "C10262-", - "G10263-", - "T10264-", - "A10265-", - "C10266-", - "A10267-", - "C10268-", - "G10269-", - "T10270-", - "T10271-", - "T10272-", - "T10273-", - "A10274-", - "A10275-", - "A10276-", - "A10277-", - "A10278-", - "A10279-", - "A10280-", - "T10281-", - "A10282-", - "A10283-", - "C10284-", - "A10285-", - "A10286-", - "T10287-", - "G10288-", - "A10289-", - "G10290-", - "C10291-", - "A10292-", - "A10293-", - "G10294-", - "T10295-", - "T10296-", - "C10297-", - "T10298-", - "A10299-", - "T10300-", - "A10301-", - "A10302-", - "G10303-", - "C10304-", - "T10305-", - "A10306-", - "G10307-", - "T10308-", - "T10309-", - "A10310-", - "A10311-", - "C10312-", - "T10313-", - "A10314-", - "A10315-", - "T10316-", - "A10317-", - "A10318-", - "A10319-", - "T10320-", - "A10321-", - "A10322-", - "A10323-", - "A10324-", - "A10325-", - "G10326-", - "T10327-", - "T10328-", - "T10329-", - "A10330-", - "A10331-", - "T10332-", - "T10333-", - "A10334-", - "T10335-", - "C10336-", - "G10337-", - "A10338-", - "C10339-", - "G10340-", - "A10341-", - "T10342-", - "A10343-", - "T10344-", - "A10345-", - "T10346-", - "G10347-", - "T10348-", - "C10349-", - "G10350-", - "T10351-", - "T10352-", - "A10353-", - "T10354-", - "T10355-", - "T10356-", - "T10357-", - "T10358-", - "C10359-", - "T10360-", - "C10361-", - "T10362-", - "C10363-", - "A10364-", - "T10365-", - "A10366-", - "T10367-", - "G10368-", - "A10369-", - "A10370-", - "A10371-", - "G10372-", - "A10373-", - "T10374-", - "T10375-", - "A10376-", - "A10377-", - "T10378-", - "T10379-", - "T10380-", - "G10381-", - "A10382-", - "T10383-", - "T10384-", - "C10385-", - "T10386-", - "A10387-", - "A10388-", - "T10389-", - "A10390-", - "T10391-", - "A10392-", - "A10393-", - "T10394-", - "C10395-", - "T10396-", - "T10397-", - "C10398-", - "A10399-", - "G10400-", - "T10401-", - "A10402-", - "T10403-", - "T10404-", - "G10405-", - "G10406-", - "A10407-", - "T10408-", - "G10409-", - "A10410-", - "A10411-", - "T10412-", - "C10413-", - "T10414-", - "C10415-", - "A10416-", - "A10417-", - "T10418-", - "T10419-", - "C10420-", - "A10421-", - "A10422-", - "A10423-", - "T10424-", - "T10425-", - "A10426-", - "A10427-", - "T10428-", - "T10429-", - "C10430-", - "C10431-", - "A10432-", - "T10433-", - "T10434-", - "A10435-", - "G10436-", - "A10437-", - "T10438-", - "T10439-", - "A10440-", - "G10441-", - "A10442-", - "T10443-", - "T10444-", - "A10445-", - "G10446-", - "A10447-", - "T10448-", - "T10449-", - "A10450-", - "G10451-", - "A10452-", - "T10453-", - "C10454-", - "A10455-", - "T10456-", - "A10457-", - "A10458-", - "A10459-", - "T10460-", - "A10461-", - "A10462-", - "A10463-", - "A10464-", - "A10465-", - "T10466-", - "A10467-", - "G10468-", - "T10469-", - "A10470-", - "G10471-", - "C10472-", - "A10473-", - "C10474-", - "G10475-", - "C10476-", - "A10477-", - "C10478-", - "T10479-", - "A10480-", - "C10481-", - "T10482-", - "T10483-", - "C10484-", - "A10485-", - "G10486-", - "C10487-", - "C10488-", - "A10489-", - "A10490-", - "A10491-", - "T10492-", - "A10493-", - "T10494-", - "T10495-", - "C10496-", - "T10497-", - "T10498-", - "T10499-", - "T10500-", - "T10501-", - "T10502-", - "G10503-", - "A10504-", - "A10505-", - "A10506-", - "C10507-", - "G10508-", - "C10509-", - "C10510-", - "A10511-", - "T10512-", - "C10513-", - "T10514-", - "A10515-", - "G10516-", - "C10517-", - "G10518-", - "T10519-", - "A10520-", - "A10521-", - "T10522-", - "G10523-", - "A10524-", - "G10525-", - "A10526-", - "A10527-", - "C10528-", - "A10529-", - "C10530-", - "A10531-", - "A10532-", - "G10533-", - "T10534-", - "G10535-", - "A10536-", - "A10537-", - "C10538-", - "C10539-", - "T10540-", - "A10541-", - "T10542-", - "A10543-", - "A10544-", - "T10545-", - "G10546-", - "A10547-", - "G10548-", - "C10549-", - "A10550-", - "A10551-", - "A10552-", - "T10553-", - "T10554-", - "T10555-", - "A10556-", - "T10557-", - "T10558-", - "A10559-", - "G10560-", - "T10561-", - "A10562-", - "T10563-", - "C10564-", - "G10565-", - "G10566-", - "T10567-", - "T10568-", - "A10569-", - "C10570-", - "A10571-", - "T10572-", - "G10573-", - "A10574-", - "A10575-", - "G10576-", - "G10577-", - "A10578-", - "C10579-", - "T10580-", - "T10581-", - "T10582-", - "A10583-", - "C10584-", - "G10585-", - "T10586-", - "A10587-", - "G10588-", - "A10589-", - "G10590-", - "T10591-", - "G10592-", - "G10593-", - "T10594-", - "G10595-", - "A10596-", - "T10597-", - "T10598-", - "C10599-", - "C10600-", - "T10601-", - "C10602-", - "C10603-", - "A10604-", - "T10605-", - "C10606-", - "T10607-", - "G10608-", - "T10609-", - "G10610-", - "G10611-", - "T10612-", - "A10613-", - "C10614-", - "G10615-", - "A10616-", - "A10617-", - "C10618-", - "G10619-", - "G10620-", - "T10621-", - "T10622-", - "T10623-", - "C10624-", - "A10625-", - "T10626-", - "C10627-", - "T10628-", - "T10629-", - "C10630-", - "T10631-", - "T10632-", - "T10633-", - "G10634-", - "A10635-", - "T10636-", - "G10637-", - "C10638-", - "C10639-", - "A10640-", - "C10641-", - "C10642-", - "A10643-", - "C10644-", - "C10645-", - "C10646-", - "A10647-", - "G10648-", - "A10649-", - "T10650-", - "G10651-", - "T10652-", - "T10653-", - "C10654-", - "T10655-", - "A10656-", - "T10657-", - "A10658-", - "A10659-", - "A10660-", - "C10661-", - "T10662-", - "T10663-", - "G10664-", - "G10665-", - "T10666-", - "A10667-", - "T10668-", - "C10669-", - "C10670-", - "T10671-", - "C10672-", - "G10673-", - "T10674-", - "C10675-", - "C10676-", - "G10677-", - "A10678-", - "T10679-", - "T10680-", - "T10681-", - "C10682-", - "A10683-", - "T10684-", - "A10685-", - "T10686-", - "C10687-", - "A10688-", - "T10689-", - "T10690-", - "T10691-", - "G10692-", - "C10693-", - "C10694-", - "A10695-", - "A10696-", - "C10697-", - "C10698-", - "A10699-", - "A10700-", - "T10701-", - "A10702-", - "C10703-", - "A10704-", - "T10705-", - "A10706-", - "T10707-", - "A10708-", - "G10709-", - "C10710-", - "T10711-", - "A10712-", - "A10713-", - "A10714-", - "C10715-", - "C10716-", - "C10717-", - "A10718-", - "G10719-", - "G10720-", - "C10721-", - "A10722-", - "T10723-", - "A10724-", - "C10725-", - "G10726-", - "T10727-", - "T10728-", - "C10729-", - "C10730-", - "A10731-", - "C10732-", - "A10733-", - "C10734-", - "A10735-", - "T10736-", - "C10737-", - "C10738-", - "G10739-", - "G10740-", - "A10741-", - "A10742-", - "C10743-", - "A10744-", - "A10745-", - "T10746-", - "G10747-", - "A10748-", - "A10749-", - "A10750-", - "T10751-", - "T10752-", - "C10753-", - "T10754-", - "C10755-", - "C10756-", - "A10757-", - "G10758-", - "A10759-", - "A10760-", - "G10761-", - "A10762-", - "T10763-", - "G10764-", - "T10765-", - "T10766-", - "A10767-", - "C10768-", - "A10769-", - "A10770-", - "T10771-", - "G10772-", - "G10773-", - "C10774-", - "T10775-", - "A10776-", - "G10777-", - "A10778-", - "T10779-", - "T10780-", - "T10781-", - "G10782-", - "G10783-", - "A10784-", - "C10785-", - "A10786-", - "T10787-", - "T10788-", - "T10789-", - "G10790-", - "G10791-", - "T10792-", - "T10793-", - "T10794-", - "C10795-", - "A10796-", - "A10797-", - "C10798-", - "C10799-", - "G10800-", - "C10801-", - "G10802-", - "T10803-", - "T10804-", - "A10805-", - "A10806-", - "C10807-", - "A10808-", - "T10809-", - "A10810-", - "T10811-", - "G10812-", - "A10813-", - "G10814-", - "T10815-", - "G10816-", - "A10817-", - "A10818-", - "C10819-", - "A10820-", - "C10821-", - "A10822-", - "C10823-", - "C10824-", - "C10825-", - "A10826-", - "T10827-", - "A10828-", - "C10829-", - "A10830-", - "T10831-", - "G10832-", - "A10833-", - "A10834-", - "A10835-", - "G10836-", - "C10837-", - "G10838-", - "A10839-", - "T10840-", - "G10841-", - "A10842-", - "G10843-", - "A10844-", - "A10845-", - "A10846-", - "T10847-", - "A10848-", - "G10849-", - "G10850-", - "A10851-", - "T10852-", - "T10853-", - "C10854-", - "T10855-", - "C10856-", - "A10857-", - "T10858-", - "C10859-", - "T10860-", - "T10861-", - "G10862-", - "C10863-", - "C10864-", - "A10865-", - "A10866-", - "A10867-", - "A10868-", - "T10869-", - "A10870-", - "T10871-", - "C10872-", - "A10873-", - "C10874-", - "T10875-", - "A10876-", - "T10877-", - "A10878-", - "A10879-", - "A10880-", - "A10881-", - "A10882-", - "A10883-", - "T10884-", - "T10885-", - "T10886-", - "A10887-", - "T10888-", - "T10889-", - "T10890-", - "A10891-", - "T10892-", - "C10893-", - "A10894-", - "A10895-", - "T10896-", - "T10897-", - "T10898-", - "T10899-", - "A10900-", - "A10901-", - "A10902-", - "G10903-", - "G10904-", - "T10905-", - "A10906-", - "T10907-", - "A10908-", - "A10909-", - "A10910-", - "A10911-", - "A10912-", - "A10913-", - "A10914-", - "T10915-", - "A10916-", - "C10917-", - "T10918-", - "T10919-", - "A10920-", - "T10921-", - "T10922-", - "G10923-", - "T10924-", - "T10925-", - "G10926-", - "C10927-", - "T10928-", - "C10929-", - "G10930-", - "A10931-", - "A10932-", - "T10933-", - "A10934-", - "T10935-", - "T10936-", - "T10937-", - "T10938-", - "G10939-", - "T10940-", - "A10941-", - "T10942-", - "T10943-", - "T10944-", - "G10945-", - "A10946-", - "T10947-", - "G10948-", - "G10949-", - "T10950-", - "A10951-", - "T10952-", - "A10953-", - "C10954-", - "G10955-", - "G10956-", - "A10957-", - "A10958-", - "G10959-", - "A10960-", - "T10961-", - "T10962-", - "A10963-", - "G10964-", - "A10965-", - "A10966-", - "A10967-", - "T10968-", - "G10969-", - "T10970-", - "A10971-", - "G10972-", - "G10973-", - "T10974-", - "A10975-", - "T10976-", - "T10977-", - "A10978-", - "T10979-", - "C10980-", - "A10981-", - "T10982-", - "C10983-", - "A10984-", - "A10985-", - "C10986-", - "T10987-", - "G10988-", - "A10989-", - "T10990-", - "T10991-", - "T10992-", - "T10993-", - "A10994-", - "T10995-", - "G10996-", - "A10997-", - "T10998-", - "G10999-", - "G11000-", - "T11001-", - "T11002-", - "T11003-", - "T11004-", - "A11005-", - "T11006-", - "G11007-", - "A11008-", - "A11009-", - "T11010-", - "T11011-", - "T11012-", - "T11013-", - "A11014-", - "T11015-", - "T11016-", - "A11017-", - "T11018-", - "G11019-", - "C11020-", - "T11021-", - "T11022-", - "C11023-", - "A11024-", - "C11025-", - "T11026-", - "A11027-", - "T11028-", - "T11029-", - "G11030-", - "C11031-", - "A11032-", - "T11033-", - "C11034-", - "G11035-", - "G11036-", - "A11037-", - "A11038-", - "A11039-", - "T11040-", - "A11041-", - "A11042-", - "T11043-", - "A11044-", - "T11045-", - "C11046-", - "A11047-", - "T11048-", - "A11049-", - "T11050-", - "G11051-", - "C11052-", - "T11053-", - "T11054-", - "C11055-", - "C11056-", - "A11057-", - "C11058-", - "G11059-", - "T11060-", - "A11061-", - "T11062-", - "A11063-", - "T11064-", - "T11065-", - "T11066-", - "T11067-", - "A11068-", - "T11069-", - "T11070-", - "T11071-", - "T11072-", - "G11073-", - "T11074-", - "T11075-", - "T11076-", - "T11077-", - "G11078-", - "A11079-", - "C11080-", - "T11081-", - "C11082-", - "A11083-", - "T11084-", - "A11085-", - "A11086-", - "T11087-", - "A11088-", - "C11089-", - "G11090-", - "C11091-", - "A11092-", - "C11093-", - "G11094-", - "T11095-", - "A11096-", - "A11097-", - "T11098-", - "T11099-", - "C11100-", - "T11101-", - "G11102-", - "G11103-", - "A11104-", - "T11105-", - "T11106-", - "A11107-", - "T11108-", - "T11109-", - "G11110-", - "G11111-", - "C11112-", - "A11113-", - "T11114-", - "A11115-", - "T11116-", - "C11117-", - "G11118-", - "A11119-", - "T11120-", - "G11121-", - "A11122-", - "A11123-", - "T11124-", - "A11125-", - "A11126-", - "T11127-", - "T11128-", - "T11129-", - "T11130-", - "A11131-", - "G11132-", - "C11133-", - "T11134-", - "C11135-", - "C11136-", - "A11137-", - "T11138-", - "G11139-", - "C11140-", - "T11141-", - "C11142-", - "A11143-", - "G11144-", - "T11145-", - "A11146-", - "A11147-", - "A11148-", - "T11149-", - "A11150-", - "T11151-", - "T11152-", - "A11153-", - "A11154-", - "T11155-", - "G11156-", - "A11157-", - "G11158-", - "A11159-", - "A11160-", - "C11161-", - "A11162-", - "T11163-", - "A11164-", - "G11165-", - "T11166-", - "G11167-", - "T11168-", - "T11169-", - "G11170-", - "C11171-", - "C11172-", - "T11173-", - "C11174-", - "C11175-", - "T11176-", - "A11177-", - "C11178-", - "C11179-", - "A11180-", - "T11181-", - "T11182-", - "A11183-", - "T11184-", - "T11185-", - "T11186-", - "T11187-", - "T11188-", - "T11189-", - "T11190-", - "C11191-", - "A11192-", - "T11193-", - "C11194-", - "T11195-", - "C11196-", - "A11197-", - "T11198-", - "T11199-", - "C11200-", - "A11201-", - "A11202-", - "T11203-", - "T11204-", - "C11205-", - "T11206-", - "T11207-", - "G11208-", - "A11209-", - "T11210-", - "T11211-", - "G11212-", - "C11213-", - "A11214-", - "G11215-", - "A11216-", - "G11217-", - "A11218-", - "T11219-", - "C11220-", - "T11221-", - "A11222-", - "T11223-", - "A11224-", - "T11225-", - "A11226-", - "A11227-", - "T11228-", - "C11229-", - "A11230-", - "T11231-", - "T11232-", - "A11233-", - "T11234-", - "A11235-", - "G11236-", - "C11237-", - "G11238-", - "T11239-", - "T11240-", - "G11241-", - "A11242-", - "C11243-", - "T11244-", - "T11245-", - "A11246-", - "T11247-", - "G11248-", - "G11249-", - "A11250-", - "C11251-", - "T11252-", - "C11253-", - "T11254-", - "G11255-", - "G11256-", - "A11257-", - "A11258-", - "T11259-", - "C11260-", - "T11261-", - "T11262-", - "A11263-", - "G11264-", - "A11265-", - "C11266-", - "G11267-", - "A11268-", - "T11269-", - "G11270-", - "T11271-", - "A11272-", - "C11273-", - "A11274-", - "G11275-", - "T11276-", - "C11277-", - "A11278-", - "T11279-", - "C11280-", - "T11281-", - "A11282-", - "T11283-", - "A11284-", - "A11285-", - "T11286-", - "C11287-", - "A11288-", - "T11289-", - "G11290-", - "G11291-", - "T11292-", - "A11293-", - "T11294-", - "A11295-", - "T11296-", - "T11297-", - "T11298-", - "A11299-", - "A11300-", - "T11301-", - "A11302-", - "C11303-", - "A11304-", - "T11305-", - "T11306-", - "G11307-", - "T11308-", - "T11309-", - "T11310-", - "T11311-", - "A11312-", - "T11313-", - "A11314-", - "G11315-", - "C11316-", - "A11317-", - "T11318-", - "A11319-", - "G11320-", - "G11321-", - "C11322-", - "A11323-", - "T11324-", - "T11325-", - "A11326-", - "T11327-", - "C11328-", - "T11329-", - "A11330-", - "C11331-", - "G11332-", - "A11333-", - "T11334-", - "A11335-", - "T11336-", - "T11337-", - "A11338-", - "G11339-", - "A11340-", - "T11341-", - "A11342-", - "C11343-", - "T11344-", - "T11345-", - "C11346-", - "A11347-", - "C11348-", - "T11349-", - "C11350-", - "A11351-", - "A11352-", - "T11353-", - "G11354-", - "A11355-", - "A11356-", - "T11357-", - "C11358-", - "A11359-", - "A11360-", - "T11361-", - "C11362-", - "A11363-", - "C11364-", - "A11365-", - "C11366-", - "A11367-", - "A11368-", - "T11369-", - "C11370-", - "T11371-", - "A11372-", - "A11373-", - "T11374-", - "G11375-", - "T11376-", - "A11377-", - "G11378-", - "G11379-", - "T11380-", - "T11381-", - "T11382-", - "A11383-", - "T11384-", - "G11385-", - "A11386-", - "C11387-", - "A11388-", - "T11389-", - "A11390-", - "A11391-", - "T11392-", - "A11393-", - "G11394-", - "C11395-", - "A11396-", - "T11397-", - "T11398-", - "T11399-", - "T11400-", - "C11401-", - "A11402-", - "G11403-", - "C11404-", - "A11405-", - "G11406-", - "T11407-", - "T11408-", - "C11409-", - "A11410-", - "A11411-", - "T11412-", - "G11413-", - "T11414-", - "T11415-", - "T11416-", - "C11417-", - "T11418-", - "A11419-", - "G11420-", - "A11421-", - "T11422-", - "T11423-", - "C11424-", - "G11425-", - "T11426-", - "T11427-", - "G11428-", - "A11429-", - "T11430-", - "G11431-", - "G11432-", - "C11433-", - "A11434-", - "A11435-", - "T11436-", - "G11437-", - "G11438-", - "T11439-", - "T11440-", - "A11441-", - "T11442-", - "A11443-", - "C11444-", - "A11445-", - "T11446-", - "G11447-", - "T11448-", - "A11449-", - "T11450-", - "A11451-", - "T11452-", - "C11453-", - "C11454-", - "G11455-", - "T11456-", - "T11457-", - "A11458-", - "T11459-", - "T11460-", - "T11461-", - "G11462-", - "A11463-", - "T11464-", - "C11465-", - "T11466-", - "A11467-", - "A11468-", - "T11469-", - "G11470-", - "T11471-", - "T11472-", - "G11473-", - "A11474-", - "C11475-", - "A11476-", - "T11477-", - "C11478-", - "T11479-", - "G11480-", - "A11481-", - "A11482-", - "C11483-", - "C11484-", - "G11485-", - "G11486-", - "A11487-", - "T11488-", - "T11489-", - "C11490-", - "T11491-", - "A11492-", - "G11493-", - "C11494-", - "A11495-", - "G11496-", - "T11497-", - "A11498-", - "A11499-", - "A11500-", - "G11501-", - "A11502-", - "T11503-", - "A11504-", - "C11505-", - "T11506-", - "A11507-", - "G11508-", - "A11509-", - "G11510-", - "A11511-", - "T11512-", - "T11513-", - "G11514-", - "T11515-", - "T11516-", - "T11517-", - "A11518-", - "T11519-", - "T11520-", - "A11521-", - "T11522-", - "A11523-", - "T11524-", - "C11525-", - "T11526-", - "A11527-", - "A11528-", - "C11529-", - "A11530-", - "G11531-", - "C11532-", - "C11533-", - "T11534-", - "T11535-", - "G11536-", - "T11537-", - "G11538-", - "A11539-", - "A11540-", - "G11541-", - "A11542-", - "A11543-", - "G11544-", - "T11545-", - "G11546-", - "T11547-", - "T11548-", - "T11549-", - "C11550-", - "T11551-", - "C11552-", - "C11553-", - "T11554-", - "C11555-", - "G11556-", - "T11557-", - "T11558-", - "T11559-", - "G11560-", - "T11561-", - "C11562-", - "A11563-", - "A11564-", - "T11565-", - "C11566-", - "A11567-", - "T11568-", - "G11569-", - "T11570-", - "T11571-", - "A11572-", - "A11573-", - "T11574-", - "G11575-", - "T11576-", - "C11577-", - "T11578-", - "T11579-", - "T11580-", - "A11581-", - "A11582-", - "G11583-", - "A11584-", - "T11585-", - "A11586-", - "A11587-", - "G11588-", - "G11589-", - "T11590-", - "A11591-", - "G11592-", - "A11593-", - "C11594-", - "A11595-", - "A11596-", - "A11597-", - "T11598-", - "G11599-", - "T11600-", - "T11601-", - "T11602-", - "A11603-", - "T11604-", - "A11605-", - "G11606-", - "T11607-", - "A11608-", - "C11609-", - "T11610-", - "A11611-", - "A11612-", - "G11613-", - "A11614-", - "A11615-", - "T11616-", - "T11617-", - "G11618-", - "G11619-", - "G11620-", - "C11621-", - "A11622-", - "A11623-", - "A11624-", - "C11625-", - "A11626-", - "T11627-", - "A11628-", - "A11629-", - "G11630-", - "A11631-", - "C11632-", - "A11633-", - "T11634-", - "G11635-", - "T11636-", - "C11637-", - "A11638-", - "C11639-", - "A11640-", - "A11641-", - "A11642-", - "G11643-", - "A11644-", - "C11645-", - "C11646-", - "C11647-", - "T11648-", - "T11649-", - "T11650-", - "T11651-", - "T11652-", - "G11653-", - "T11654-", - "A11655-", - "T11656-", - "G11657-", - "T11658-", - "A11659-", - "T11660-", - "A11661-", - "A11662-", - "G11663-", - "T11664-", - "G11665-", - "T11666-", - "A11667-", - "G11668-", - "A11669-", - "A11670-", - "A11671-", - "T11672-", - "T11673-", - "A11674-", - "T11675-", - "A11676-", - "A11677-", - "C11678-", - "A11679-", - "T11680-", - "C11681-", - "C11682-", - "A11683-", - "T11684-", - "A11685-", - "G11686-", - "T11687-", - "T11688-", - "G11689-", - "G11690-", - "A11691-", - "T11692-", - "T11693-", - "C11694-", - "A11695-", - "C11696-", - "A11697-", - "T11698-", - "A11699-", - "G11700-", - "G11701-", - "T11702-", - "G11703-", - "T11704-", - "C11705-", - "C11706-", - "A11707-", - "A11708-", - "T11709-", - "C11710-", - "G11711-", - "G11712-", - "G11713-", - "A11714-", - "T11715-", - "C11716-", - "T11717-", - "C11718-", - "T11719-", - "C11720-", - "C11721-", - "C11727T", - "C39139T", - "-173274A", - "-173275T", - "-173276A", - "-173277T", - "-173278A", - "-173279T", - "-173280A", - "-173281T", - "-173282A", - "-173283T", - "-173284A", - "-173285T", - "-173286A", - "-173287T", - "-173288A", - "-173289T", - "-173290A", - "-173291T", - "-173292A", - "-173293T", - "-173294A", - "-173295T", - "-173296A", - "-173297T", - "-173298A", - "-173299T", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-", - "A185257-", - "T185258-", - "A185259-", - "G185260-", - "A185261-", - "A185262-", - "T185263-", - "G185264-", - "T185265-", - "T185266-", - "T185267-", - "G185268-", - "C185269-", - "C185270-", - "A185271-", - "C185272-", - "A185273-", - "T185274-", - "T185275-", - "G185276-", - "G185277-", - "C185278-", - "T185279-", - "A185280-", - "G185281-", - "A185282-", - "G185283-", - "G185284-", - "A185285-", - "A185286-", - "T185287-", - "G185288-", - "C185289-", - "C185290-", - "G185291-", - "T185292-", - "T185293-", - "T185294-", - "A185295-", - "G185296-", - "A185297-", - "T185298-", - "C185299-", - "A185300-", - "A185301-", - "C185302-", - "G185303-", - "T185304-", - "A185305-", - "T185306-", - "T185307-", - "G185308-", - "C185309-", - "G185310-", - "A185311-", - "T185312-", - "A185313-", - "A185314-", - "C185315-", - "A185316-", - "G185317-", - "A185318-", - "C185319-", - "G185320-", - "A185321-", - "C185322-", - "G185323-", - "A185324-", - "T185325-", - "C185326-", - "A185327-", - "G185328-", - "G185329-", - "T185330-", - "T185331-", - "G185332-", - "T185333-", - "T185334-", - "A185335-", - "T185336-", - "T185337-", - "A185338-", - "T185339-", - "G185340-", - "C185341-", - "A185342-", - "G185343-", - "G185344-", - "A185345-", - "A185346-", - "T185347-", - "A185348-", - "C185349-", - "C185350-", - "A185351-", - "T185352-", - "T185353-", - "T185354-", - "C185355-", - "A185356-", - "T185357-", - "G185358-", - "A185359-", - "A185360-", - "G185361-", - "A185362-", - "T185363-", - "A185364-", - "G185365-", - "T185366-", - "G185367-", - "T185368-", - "A185369-", - "G185370-", - "A185371-", - "A185372-", - "A185373-", - "C185374-", - "A185375-", - "G185376-", - "A185377-", - "T185378-", - "A185379-", - "T185380-", - "A185381-", - "C185382-", - "A185383-", - "T185384-", - "T185385-", - "A185386-", - "T185387-", - "G185388-", - "G185389-", - "A185390-", - "C185391-", - "C185392-", - "A185393-", - "G185394-", - "A185395-", - "A185396-", - "A185397-", - "T185398-", - "A185399-", - "A185400-", - "T185401-", - "G185402-", - "T185403-", - "T185404-", - "A185405-", - "A185406-", - "A185407-", - "G185408-", - "G185409-", - "A185410-", - "A185411-", - "A185412-", - "C185413-", - "A185414-", - "T185415-", - "A185416-", - "T185417-", - "G185418-", - "A185419-", - "C185420-", - "A185421-", - "T185422-", - "A185423-", - "A185424-", - "A185425-", - "C185426-", - "A185427-", - "G185428-", - "T185429-", - "A185430-", - "T185431-", - "T185432-", - "G185433-", - "A185434-", - "C185435-", - "C185436-", - "C185437-", - "A185438-", - "C185439-", - "G185440-", - "A185441-", - "G185442-", - "T185443-", - "T185444-", - "A185445-", - "T185446-", - "A185447-", - "A185448-", - "C185449-", - "A185450-", - "A185451-", - "A185452-", - "G185453-", - "T185454-", - "C185455-", - "A185456-", - "A185457-", - "A185458-", - "G185459-", - "A185460-", - "C185461-", - "C185462-", - "C185463-", - "A185464-", - "T185465-", - "T185466-", - "T185467-", - "T185468-", - "C185469-", - "C185470-", - "T185471-", - "G185472-", - "C185473-", - "T185474-", - "C185475-", - "C185476-", - "A185477-", - "T185478-", - "T185479-", - "G185480-", - "A185481-", - "G185482-", - "T185483-", - "G185484-", - "T185485-", - "A185486-", - "A185487-", - "A185488-", - "A185489-", - "T185490-", - "T185491-", - "C185492-", - "A185493-", - "T185494-", - "G185495-", - "G185496-", - "T185497-", - "T185498-", - "G185499-", - "A185500-", - "C185501-", - "A185502-", - "A185503-", - "T185504-", - "T185505-", - "T185506-", - "A185507-", - "G185508-", - "G185509-", - "A185510-", - "A185511-", - "A185512-", - "T185513-", - "G185514-", - "G185515-", - "A185516-", - "T185517-", - "A185518-", - "T185519-", - "G185520-", - "A185521-", - "C185522-", - "A185523-", - "A185524-", - "C185525-", - "C185526-", - "C185527-", - "T185528-", - "A185529-", - "A185530-", - "T185531-", - "T185532-", - "C185533-", - "A185534-", - "T185535-", - "T185536-", - "T185537-", - "T185538-", - "G185539-", - "G185540-", - "G185541-", - "A185542-", - "A185543-", - "G185544-", - "A185545-", - "T185546-", - "G185547-", - "C185548-", - "T185549-", - "A185550-", - "A185551-", - "A185552-", - "A185553-", - "C185554-", - "T185555-", - "A185556-", - "A185557-", - "G185558-", - "A185559-", - "A185560-", - "A185561-", - "C185562-", - "G185563-", - "G185564-", - "A185565-", - "C185566-", - "A185567-", - "T185568-", - "A185569-", - "T185570-", - "A185571-", - "G185572-", - "T185573-", - "G185574-", - "C185575-", - "A185576-", - "A185577-", - "T185578-", - "G185579-", - "A185580-", - "C185581-", - "G185582-", - "A185583-", - "T185584-", - "A185585-", - "A185586-", - "A185587-", - "A185588-", - "G185589-", - "T185590-", - "C185591-", - "C185592-", - "T185593-", - "A185594-", - "C185595-", - "C185596-", - "A185597-", - "T185598-", - "G185599-", - "T185600-", - "A185601-", - "C185602-", - "A185603-", - "G185604-", - "T185605-", - "G185606-", - "A185607-", - "G185608-", - "A185609-", - "A185610-", - "A185611-", - "T185612-", - "A185613-", - "A185614-", - "A185615-", - "A185616-", - "A185617-", - "T185618-", - "A185619-", - "T185620-", - "A185621-", - "G185622-", - "A185623-", - "C185624-", - "T185625-", - "T185626-", - "T185627-", - "G185628-", - "G185629-", - "A185630-", - "T185631-", - "A185632-", - "T185633-", - "A185634-", - "A185635-", - "C185636-", - "T185637-", - "A185638-", - "T185639-", - "G185640-", - "G185641-", - "A185642-", - "G185643-", - "A185644-", - "T185645-", - "A185646-", - "T185647-", - "T185648-", - "A185649-", - "T185650-", - "T185651-", - "T185652-", - "C185653-", - "T185654-", - "A185655-", - "A185656-", - "T185657-", - "A185658-", - "T185659-", - "G185660-", - "G185661-", - "T185662-", - "T185663-", - "T185664-", - "A185665-", - "T185666-", - "C185667-", - "T185668-", - "A185669-", - "C185670-", - "A185671-", - "A185672-", - "T185673-", - "C185674-", - "T185675-", - "A185676-", - "C185677-", - "T185678-", - "A185679-", - "G185680-", - "T185681-", - "C185682-", - "A185683-", - "G185684-", - "G185685-", - "A185686-", - "T185687-", - "T185688-", - "A185689-", - "T185690-", - "G185691-", - "G185692-", - "A185693-", - "G185694-", - "A185695-", - "T185696-", - "G185697-", - "G185698-", - "T185699-", - "A185700-", - "C185701-", - "C185702-", - "A185703-", - "A185704-", - "A185705-", - "T185706-", - "A185707-", - "T185708-", - "A185709-", - "C185710-", - "A185711-", - "T185712-", - "T185713-", - "T185714-", - "A185715-", - "A185716-", - "A185717-", - "T185718-", - "C185719-", - "C185720-", - "G185721-", - "T185722-", - "A185723-", - "A185724-", - "C185725-", - "T185726-", - "A185727-", - "G185728-", - "A185729-", - "T185730-", - "C185731-", - "A185732-", - "G185733-", - "A185734-", - "T185735-", - "C185736-", - "A185737-", - "T185738-", - "G185739-", - "A185740-", - "G185741-", - "T185742-", - "G185743-", - "T185744-", - "G185745-", - "A185746-", - "A185747-", - "T185748-", - "C185749-", - "T185750-", - "A185751-", - "G185752-", - "C185753-", - "T185754-", - "T185755-", - "A185756-", - "G185757-", - "A185758-", - "T185759-", - "C185760-", - "T185761-", - "A185762-", - "A185763-", - "C185764-", - "G185765-", - "T185766-", - "C185767-", - "T185768-", - "A185769-", - "A185770-", - "G185771-", - "G185772-", - "A185773-", - "A185774-", - "G185775-", - "T185776-", - "A185777-", - "A185778-", - "C185779-", - "T185780-", - "G185781-", - "T185782-", - "G185783-", - "A185784-", - "C185785-", - "A185786-", - "T185787-", - "G185788-", - "T185789-", - "C185790-", - "C185791-", - "T185792-", - "G185793-", - "C185794-", - "G185795-", - "T185796-", - "T185797-", - "T185798-", - "A185799-", - "G185800-", - "T185801-", - "A185802-", - "T185803-", - "A185804-", - "C185805-", - "C185806-", - "A185807-", - "A185808-", - "G185809-", - "A185810-", - "A185811-", - "A185812-", - "T185813-", - "A185814-", - "T185815-", - "A185816-", - "T185817-", - "C185818-", - "A185819-", - "A185820-", - "C185821-", - "A185822-", - "T185823-", - "A185824-", - "T185825-", - "G185826-", - "A185827-", - "A185828-", - "G185829-", - "G185830-", - "T185831-", - "C185832-", - "T185833-", - "A185834-", - "T185835-", - "G185836-", - "C185837-", - "T185838-", - "T185839-", - "T185840-", - "A185841-", - "G185842-", - "T185843-", - "G185844-", - "T185845-", - "T185846-", - "A185847-", - "C185848-", - "T185849-", - "A185850-", - "C185851-", - "A185852-", - "T185853-", - "C185854-", - "T185855-", - "A185856-", - "A185857-", - "A185858-", - "G185859-", - "A185860-", - "T185861-", - "C185862-", - "A185863-", - "T185864-", - "T185865-", - "G185866-", - "T185867-", - "G185868-", - "C185869-", - "T185870-", - "A185871-", - "C185872-", - "A185873-", - "G185874-", - "G185875-", - "T185876-", - "A185877-", - "T185878-", - "T185879-", - "G185880-", - "G185881-", - "T185882-", - "T185883-", - "G185884-", - "G185885-", - "T185886-", - "T185887-", - "A185888-", - "A185889-", - "A185890-", - "A185891-", - "T185892-", - "C185893-", - "T185894-", - "A185895-", - "G185896-", - "T185897-", - "G185898-", - "G185899-", - "T185900-", - "T185901-", - "A185902-", - "T185903-", - "G185904-", - "G185905-", - "G185906-", - "A185907-", - "A185908-", - "G185909-", - "G185910-", - "A185911-", - "A185912-", - "G185913-", - "A185914-", - "T185915-", - "G185916-", - "C185917-", - "T185918-", - "G185919-", - "A185920-", - "T185921-", - "A185922-", - "A185923-", - "A185924-", - "C185925-", - "C185926-", - "A185927-", - "C185928-", - "G185929-", - "T185930-", - "G185931-", - "C185932-", - "T185933-", - "T185934-", - "G185935-", - "T185936-", - "T185937-", - "T185938-", - "T185939-", - "C185940-", - "A185941-", - "T185942-", - "C185943-", - "A185944-", - "T185945-", - "T185946-", - "G185947-", - "G185948-", - "A185949-", - "A185950-", - "T185951-", - "T185952-", - "A185953-", - "T185954-", - "T185955-", - "A185956-", - "C185957-", - "A185958-", - "C185959-", - "A185960-", - "C185961-", - "T185962-", - "G185963-", - "T185964-", - "C185965-", - "G185966-", - "T185967-", - "T185968-", - "G185969-", - "G185970-", - "A185971-", - "T185972-", - "T185973-", - "A185974-", - "T185975-", - "T185976-", - "A185977-", - "C185978-", - "T185979-", - "G185980-", - "T185981-", - "T185982-", - "C185983-", - "A185984-", - "T185985-", - "A185986-", - "C185987-", - "G185988-", - "A185989-", - "A185990-", - "G185991-", - "A185992-", - "T185993-", - "A185994-", - "T185995-", - "T185996-", - "T185997-", - "G185998-", - "G185999-", - "A186000-", - "G186001-", - "A186002-", - "A186003-", - "G186004-", - "C186005-", - "A186006-", - "C186007-", - "C186008-", - "T186009-", - "G186010-", - "G186011-", - "C186012-", - "C186013-", - "T186014-", - "G186015-", - "A186016-", - "C186017-", - "T186018-", - "A186019-", - "T186020-", - "G186021-", - "A186022-", - "T186023-", - "C186024-", - "C186025-", - "A186026-", - "T186027-", - "G186028-", - "T186029-", - "A186030-", - "A186031-", - "G186032-", - "T186033-", - "C186034-", - "A186035-", - "T186036-", - "A186037-", - "T186038-", - "A186039-", - "T186040-", - "C186041-", - "C186042-", - "A186043-", - "T186044-", - "A186045-", - "T186046-", - "A186047-", - "G186048-", - "A186049-", - "G186050-", - "T186051-", - "A186052-", - "T186053-", - "A186054-", - "G186055-", - "A186056-", - "G186057-", - "A186058-", - "T186059-", - "A186060-", - "C186061-", - "A186062-", - "T186063-", - "G186064-", - "G186065-", - "A186066-", - "T186067-", - "A186068-", - "G186069-", - "A186070-", - "A186071-", - "T186072-", - "C186073-", - "T186074-", - "A186075-", - "A186076-", - "T186077-", - "G186078-", - "T186079-", - "G186080-", - "T186081-", - "T186082-", - "A186083-", - "C186084-", - "A186085-", - "G186086-", - "C186087-", - "A186088-", - "A186089-", - "C186090-", - "C186091-", - "T186092-", - "C186093-", - "C186094-", - "T186095-", - "T186096-", - "A186097-", - "C186098-", - "A186099-", - "C186100-", - "A186101-", - "T186102-", - "T186103-", - "C186104-", - "G186105-", - "A186106-", - "A186107-", - "T186108-", - "T186109-", - "C186110-", - "A186111-", - "T186112-", - "T186113-", - "C186114-", - "A186115-", - "T186116-", - "G186117-", - "A186118-", - "C186119-", - "A186120-", - "A186121-", - "T186122-", - "T186123-", - "C186124-", - "T186125-", - "A186126-", - "A186127-", - "C186128-", - "G186129-", - "A186130-", - "A186131-", - "T186132-", - "A186133-", - "T186134-", - "G186135-", - "T186136-", - "G186137-", - "G186138-", - "A186139-", - "T186140-", - "A186141-", - "A186142-", - "A186143-", - "G186144-", - "A186145-", - "A186146-", - "A186147-", - "T186148-", - "T186149-", - "A186150-", - "G186151-", - "T186152-", - "A186153-", - "A186154-", - "C186155-", - "A186156-", - "A186157-", - "A186158-", - "T186159-", - "T186160-", - "A186161-", - "A186162-", - "A186163-", - "T186164-", - "G186165-", - "A186166-", - "T186167-", - "C186168-", - "T186169-", - "G186170-", - "T186171-", - "A186172-", - "C186173-", - "A186174-", - "A186175-", - "T186176-", - "G186177-", - "A186178-", - "A186179-", - "T186180-", - "A186181-", - "C186182-", - "A186183-", - "A186184-", - "G186185-", - "A186186-", - "A186187-", - "G186188-", - "A186189-", - "T186190-", - "T186191-", - "A186192-", - "T186193-", - "G186194-", - "G186195-", - "A186196-", - "A186197-", - "T186198-", - "A186199-", - "T186200-", - "A186201-", - "G186202-", - "C186203-", - "G186204-", - "A186205-", - "C186206-", - "G186207-", - "G186208-", - "A186209-", - "T186210-", - "C186211-", - "A186212-", - "T186213-", - "T186214-", - "G186215-", - "C186216-", - "C186217-", - "G186218-", - "G186219-", - "C186220-", - "G186221-", - "T186222-", - "C186223-", - "T186224-", - "A186225-", - "T186226-", - "A186227-", - "A186228-", - "A186229-", - "C186230-", - "A186231-", - "G186232-", - "A186233-", - "T186234-", - "T186235-", - "A186236-", - "G186237-", - "C186238-", - "A186239-", - "A186240-", - "A186241-", - "G186242-", - "G186243-", - "C186244-", - "A186245-", - "T186246-", - "T186247-", - "G186248-", - "A186249-", - "C186250-", - "T186251-", - "T186252-", - "C186253-", - "A186254-", - "G186255-", - "A186256-", - "G186257-", - "G186258-", - "G186259-", - "T186260-", - "A186261-", - "G186262-", - "A186263-", - "G186264-", - "A186265-", - "A186266-", - "A186267-", - "T186268-", - "A186269-", - "G186270-", - "C186271-", - "A186272-", - "A186273-", - "G186274-", - "T186275-", - "G186276-", - "T186277-", - "T186278-", - "A186279-", - "A186280-", - "T186281-", - "A186282-", - "T186283-", - "A186284-", - "G186285-", - "A186286-", - "T186287-", - "G186288-", - "G186289-", - "T186290-", - "A186291-", - "A186292-", - "T186293-", - "C186294-", - "T186295-", - "G186296-", - "T186297-", - "T186298-", - "A186299-", - "G186300-", - "A186301-", - "T186302-", - "A186303-", - "T186304-", - "C186305-", - "G186306-", - "C186307-", - "A186308-", - "T186309-", - "A186310-", - "T186311-", - "C186312-", - "A186313-", - "A186314-", - "G186315-", - "C186316-", - "A186317-", - "G186318-", - "A186319-", - "T186320-", - "A186321-", - "A186322-", - "G186323-", - "G186324-", - "A186325-", - "A186326-", - "A186327-", - "A186328-", - "G186329-", - "A186330-", - "T186331-", - "G186332-", - "G186333-", - "C186334-", - "C186335-", - "G186336-", - "A186337-", - "C186338-", - "A186339-", - "T186340-", - "A186341-", - "C186342-", - "A186343-", - "G186344-", - "A186345-", - "C186346-", - "A186347-", - "A186348-", - "G186349-", - "A186350-", - "A186351-", - "T186352-", - "A186353-", - "A186354-", - "A186355-", - "T186356-", - "G186357-", - "A186358-", - "T186359-", - "A186360-", - "T186361-", - "T186362-", - "A186363-", - "T186364-", - "T186365-", - "A186366-", - "G186367-", - "A186368-", - "G186369-", - "A186370-", - "T186371-", - "T186372-", - "T186373-", - "G186374-", - "T186375-", - "T186376-", - "T186377-", - "A186378-", - "T186379-", - "A186380-", - "C186381-", - "A186382-", - "C186383-", - "A186384-", - "C186385-", - "T186386-", - "C186387-", - "T186388-", - "A186389-", - "T186390-", - "C186391-", - "A186392-", - "G186393-", - "A186394-", - "C186395-", - "A186396-", - "A186397-", - "A186398-", - "G186399-", - "A186400-", - "T186401-", - "A186402-", - "T186403-", - "A186404-", - "A186405-", - "A186406-", - "A186407-", - "G186408-", - "A186409-", - "C186410-", - "A186411-", - "T186412-", - "T186413-", - "A186414-", - "T186415-", - "A186416-", - "G186417-", - "A186418-", - "A186419-", - "T186420-", - "C186421-", - "C186422-", - "G186423-", - "A186424-", - "A186425-", - "G186426-", - "A186427-", - "A186428-", - "G186429-", - "G186430-", - "T186431-", - "A186432-", - "A186433-", - "G186434-", - "A186435-", - "G186436-", - "A186437-", - "T186438-", - "G186439-", - "T186440-", - "T186441-", - "G186442-", - "T186443-", - "A186444-", - "T186445-", - "A186446-", - "A186447-", - "T186448-", - "A186449-", - "G186450-", - "A186451-", - "T186452-", - "G186453-", - "T186454-", - "T186455-", - "A186456-", - "A186457-", - "G186458-", - "A186459-", - "A186460-", - "C186461-", - "A186462-", - "A186463-", - "T186464-", - "C186465-", - "T186466-", - "T186467-", - "G186468-", - "T186469-", - "T186470-", - "A186471-", - "A186472-", - "A186473-", - "A186474-", - "A186475-", - "G186476-", - "T186477-", - "A186478-", - "C186479-", - "T186480-", - "A186481-", - "T186482-", - "T186483-", - "C186484-", - "T186485-", - "A186486-", - "T186487-", - "T186488-", - "G186489-", - "A186490-", - "T186491-", - "A186492-", - "A186493-", - "T186494-", - "T186495-", - "A186496-", - "T186497-", - "C186498-", - "T186499-", - "A186500-", - "T186501-", - "G186502-", - "T186503-", - "G186504-", - "A186505-", - "T186506-", - "A186507-", - "C186508-", - "T186509-", - "T186510-", - "T186511-", - "A186512-", - "G186513-", - "A186514-", - "T186515-", - "G186516-", - "A186517-", - "T186518-", - "T186519-", - "A186520-", - "T186521-", - "A186522-", - "T186523-", - "A186524-", - "T186525-", - "A186526-", - "C186527-", - "A186528-", - "C186529-", - "C186530-", - "T186531-", - "C186532-", - "T186533-", - "G186534-", - "T186535-", - "A186536-", - "G186537-", - "A186538-", - "A186539-", - "T186540-", - "A186541-", - "T186542-", - "A186543-", - "A186544-", - "C186545-", - "A186546-", - "A186547-", - "A186548-", - "T186549-", - "C186550-", - "C186551-", - "T186552-", - "A186553-", - "T186554-", - "G186555-", - "T186556-", - "G186557-", - "T186558-", - "T186559-", - "A186560-", - "G186561-", - "T186562-", - "A186563-", - "A186564-", - "A186565-", - "C186566-", - "G186567-", - "A186568-", - "T186569-", - "A186570-", - "C186571-", - "T186572-", - "T186573-", - "A186574-", - "T186575-", - "A186576-", - "T186577-", - "G186578-", - "A186579-", - "G186580-", - "C186581-", - "T186582-", - "A186583-", - "T186584-", - "G186585-", - "A186586-", - "C186587-", - "T186588-", - "A186589-", - "T186590-", - "C186591-", - "T186592-", - "T186593-", - "G186594-", - "A186595-", - "A186596-", - "T186597-", - "C186598-", - "A186599-", - "T186600-", - "C186601-", - "A186602-", - "G186603-", - "G186604-", - "T186605-", - "G186606-", - "T186607-", - "A186608-", - "G186609-", - "T186610-", - "T186611-", - "G186612-", - "T186613-", - "T186614-", - "C186615-", - "T186616-", - "A186617-", - "T186618-", - "C186619-", - "A186620-", - "T186621-", - "G186622-", - "T186623-", - "T186624-", - "A186625-", - "T186626-", - "G186627-", - "A186628-", - "A186629-", - "A186630-", - "T186631-", - "G186632-", - "A186633-", - "C186634-", - "T186635-", - "A186636-", - "T186637-", - "A186638-", - "A186639-", - "T186640-", - "C186641-", - "T186642-", - "C186643-", - "C186644-", - "T186645-", - "T186646-", - "G186647-", - "G186648-", - "A186649-", - "T186650-", - "A186651-", - "C186652-", - "A186653-", - "A186654-", - "A186655-", - "A186656-", - "G186657-", - "A186658-", - "C186659-", - "G186660-", - "C186661-", - "C186662-", - "A186663-", - "A186664-", - "A186665-", - "G186666-", - "A186667-", - "T186668-", - "G186669-", - "C186670-", - "T186671-", - "A186672-", - "T186673-", - "A186674-", - "G186675-", - "A186676-", - "A186677-", - "G186678-", - "A186679-", - "T186680-", - "G186681-", - "T186682-", - "G186683-", - "A186684-", - "T186685-", - "A186686-", - "G186687-", - "T186688-", - "A186689-", - "G186690-", - "C186691-", - "A186692-", - "A186693-", - "G186694-", - "T186695-", - "G186696-", - "C186697-", - "G186698-", - "G186699-", - "T186700-", - "A186701-", - "G186702-", - "C186703-", - "C186704-", - "G186705-", - "A186706-", - "A186707-", - "G186708-", - "C186709-", - "A186710-", - "T186711-", - "T186712-", - "G186713-", - "A186714-", - "A186715-", - "T186716-", - "G186717-", - "A186718-", - "C186719-", - "A186720-", - "T186721-", - "G186722-", - "T186723-", - "T186724-", - "T186725-", - "A186726-", - "A186727-", - "G186728-", - "G186729-", - "A186730-", - "A186731-", - "T186732-", - "T186733-", - "T186734-", - "G186735-", - "A186736-", - "T186737-", - "A186738-", - "A186739-", - "A186740-", - "A186741-", - "A186742-", - "C186743-", - "G186744-", - "T186745-", - "A186746-", - "A186747-", - "G186748-", - "T186749-", - "G186750-", - "C186751-", - "T186752-", - "A186753-", - "T186754-", - "T186755-", - "A186756-", - "T186757-", - "A186758-", - "A186759-", - "T186760-", - "A186761-", - "A186762-", - "A186763-", - "A186764-", - "G186765-", - "A186766-", - "A186767-", - "G186768-", - "A186769-", - "A186770-", - "G186771-", - "A186772-", - "T186773-", - "A186774-", - "A186775-", - "T186776-", - "T186777-", - "A186778-", - "T186779-", - "C186780-", - "T186781-", - "A186782-", - "A186783-", - "A186784-", - "C186785-", - "A186786-", - "G186787-", - "T186788-", - "T186789-", - "C186790-", - "G186791-", - "C186792-", - "C186793-", - "C186794-", - "G186795-", - "A186796-", - "T186797-", - "A186798-", - "T186799-", - "C186800-", - "T186801-", - "A186802-", - "C186803-", - "C186804-", - "A186805-", - "T186806-", - "A186807-", - "T186808-", - "A186809-", - "A186810-", - "T186811-", - "A186812-", - "T186813-", - "A186814-", - "T186815-", - "A186816-", - "T186817-", - "C186818-", - "A186819-", - "T186820-", - "A186821-", - "G186822-", - "G186823-", - "T186824-", - "G186825-", - "G186826-", - "C186827-", - "A186828-", - "C186829-", - "T186830-", - "A186831-", - "T186832-", - "T186833-", - "C186834-", - "T186835-", - "G186836-", - "C186837-", - "T186838-", - "A186839-", - "C186840-", - "T186841-", - "G186842-", - "T186843-", - "T186844-", - "A186845-", - "G186846-", - "T186847-", - "C186848-", - "A186849-", - "T186850-", - "T186851-", - "A186852-", - "T186853-", - "T186854-", - "T186855-", - "T186856-", - "A186857-", - "A186858-", - "T186859-", - "A186860-", - "T186861-", - "T186862-", - "G186863-", - "G186864-", - "C186865-", - "A186866-", - "A186867-", - "T186868-", - "T186869-", - "T186870-", - "A186871-", - "T186872-", - "A186873-", - "T186874-", - "A186875-", - "G186876-", - "C186877-", - "G186878-", - "C186879-", - "G186880-", - "C186881-", - "A186882-", - "A186883-", - "T186884-", - "A186885-", - "A186886-", - "A186887-", - "T186888-", - "A186889-", - "C186890-", - "A186891-", - "G186892-", - "A186893-", - "A186894-", - "C186895-", - "C186896-", - "A186897-", - "G186898-", - "G186899-", - "A186900-", - "A186901-", - "A186902-", - "T186903-", - "A186904-", - "T186905-", - "G186906-", - "A186907-", - "A186908-", - "A186909-", - "T186910-", - "A186911-", - "A186912-", - "T186913-", - "G186914-", - "A186915-", - "A186916-", - "A186917-", - "T186918-", - "A186919-", - "T186920-", - "G186921-", - "A186922-", - "C186923-", - "A186924-", - "A186925-", - "T186926-", - "A186927-", - "T186928-", - "G186929-", - "A186930-", - "G186931-", - "C186932-", - "A186933-", - "T186934-", - "T186935-", - "A186936-", - "A186937-", - "A186938-", - "T186939-", - "C186940-", - "T186941-", - "G186942-", - "A186943-", - "G186944-", - "C186945-", - "A186946-", - "T186947-", - "C186948-", - "A186949-", - "T186950-", - "G186951-", - "A186952-", - "T186953-", - "A186954-", - "G186955-", - "T186956-", - "C186957-", - "T186958-", - "T186959-", - "G186960-", - "A186961-", - "A186962-", - "A186963-", - "C186964-", - "A186965-", - "G186966-", - "T186967-", - "G186968-", - "T186969-", - "C186970-", - "T186971-", - "A186972-", - "T186973-", - "G186974-", - "G186975-", - "A186976-", - "A186977-", - "A186978-", - "T186979-", - "T186980-", - "A186981-", - "T186982-", - "T186983-", - "G186984-", - "A186985-", - "T186986-", - "A186987-", - "A186988-", - "T186989-", - "C186990-", - "G186991-", - "G186992-", - "T186993-", - "A186994-", - "C186995-", - "T186996-", - "A186997-", - "A186998-", - "T186999-", - "A187000-", - "A187001-", - "A187002-", - "A187003-", - "T187004-", - "A187005-", - "G187006-", - "T187007-", - "T187008-", - "T187009-", - "A187010-", - "A187011-", - "C187012-", - "T187013-", - "C187014-", - "T187015-", - "T187016-", - "T187017-", - "T187018-", - "A187019-", - "G187020-", - "A187021-", - "A187022-", - "C187023-", - "C187024-", - "A187025-", - "G187026-", - "T187027-", - "T187028-", - "T187029-", - "G187030-", - "G187031-", - "T187032-", - "A187033-", - "C187034-", - "T187035-", - "G187036-", - "T187037-", - "A187038-", - "A187039-", - "T187040-", - "T187041-", - "T187042-", - "C187043-", - "A187044-", - "G187045-", - "T187046-", - "T187047-", - "C187048-", - "A187049-", - "T187050-", - "T187051-", - "A187052-", - "C187053-", - "T187054-", - "C187055-", - "G187056-", - "T187057-", - "T187058-", - "G187059-", - "A187060-", - "G187061-", - "A187062-", - "A187063-", - "T187064-", - "A187065-", - "T187066-", - "T187067-", - "G187068-", - "A187069-", - "T187070-", - "G187071-", - "A187072-", - "T187073-", - "T187074-", - "T187075-", - "T187076-", - "T187077-", - "T187078-", - "T187079-", - "T187080-", - "A187081-", - "A187082-", - "A187083-", - "T187084-", - "G187085-", - "A187086-", - "G187087-", - "T187088-", - "A187089-", - "T187090-", - "C187091-", - "G187092-", - "G187093-", - "T187094-", - "A187095-", - "G187096-", - "T187097-", - "T187098-", - "A187099-", - "C187100-", - "A187101-", - "T187102-", - "A187103-", - "T187104-", - "T187105-", - "A187106-", - "C187107-", - "C187108-", - "A187109-", - "T187110-", - "A187111-", - "T187112-", - "C187113-", - "A187114-", - "T187115-", - "C187116-", - "C187117-", - "A187118-", - "T187119-", - "T187120-", - "A187121-", - "T187122-", - "A187123-", - "T187124-", - "A187125-", - "A187126-", - "T187127-", - "C187128-", - "G187129-", - "A187130-", - "T187131-", - "G187132-", - "A187133-", - "T187134-", - "G187135-", - "C187136-", - "A187137-", - "T187138-", - "G187139-", - "T187140-", - "A187141-", - "T187142-", - "T187143-", - "A187144-", - "G187145-", - "A187146-", - "A187147-", - "T187148-", - "A187149-", - "C187150-", - "T187151-", - "T187152-", - "T187153-", - "C187154-", - "C187155-", - "G187156-", - "A187157-", - "A187158-", - "T187159-", - "A187160-", - "A187161-", - "G187162-", - "T187163-", - "C187164-", - "T187165-", - "T187166-", - "C187167-", - "T187168-", - "A187169-", - "A187170-", - "A187171-", - "T187172-", - "A187173-", - "T187174-", - "T187175-", - "G187176-", - "T187177-", - "A187178-", - "T187179-", - "T187180-", - "A187181-", - "A187182-", - "T187183-", - "T187184-", - "A187185-", - "T187186-", - "G187187-", - "A187188-", - "A187189-", - "A187190-", - "A187191-", - "A187192-", - "C187193-", - "T187194-", - "A187195-", - "T187196-", - "G187197-", - "C187198-", - "T187199-", - "A187200-", - "T187201-", - "G187202-", - "T187203-", - "G187204-", - "A187205-", - "G187206-", - "T187207-", - "A187208-", - "T187209-", - "G187210-", - "A187211-", - "T187212-", - "T187213-", - "C187214-", - "A187215-", - "A187216-", - "A187217-", - "G187218-", - "A187219-", - "T187220-", - "G187221-", - "T187222-", - "T187223-", - "T187224-", - "A187225-", - "A187226-", - "T187227-", - "G187228-", - "A187229-", - "T187230-", - "A187231-", - "C187232-", - "G187233-", - "A187234-", - "T187235-", - "A187236-", - "C187237-", - "T187238-", - "A187239-", - "G187240-", - "A187241-", - "T187242-", - "T187243-", - "T187244-", - "T187245-", - "A187246-", - "T187247-", - "C187248-", - "T187249-", - "C187250-", - "T187251-", - "A187252-", - "G187253-", - "C187254-", - "G187255-", - "A187256-", - "G187257-", - "A187258-", - "T187259-", - "T187260-", - "G187261-", - "T187262-", - "T187263-", - "T187264-", - "A187265-", - "G187266-", - "A187267-", - "A187268-", - "T187269-", - "C187270-", - "A187271-", - "T187272-", - "T187273-", - "T187274-", - "A187275-", - "T187276-", - "C187277-", - "A187278-", - "T187279-", - "A187280-", - "A187281-", - "C187282-", - "T187283-", - "A187284-", - "T187285-", - "G187286-", - "T187287-", - "T187288-", - "T187289-", - "A187290-", - "A187291-", - "T187292-", - "A187293-", - "A187294-", - "A187295-", - "T187296-", - "T187297-", - "C187298-", - "A187299-", - "T187300-", - "C187301-", - "A187302-", - "A187303-", - "C187304-", - "G187305-", - "A187306-", - "A187307-", - "T187308-", - "A187309-", - "T187310-", - "C187311-", - "G187312-", - "A187313-", - "T187314-", - "A187315-", - "A187316-", - "A187317-", - "G187318-", - "A187319-", - "C187320-", - "C187321-", - "T187322-", - "C187323-", - "T187324-", - "T187325-", - "G187326-", - "T187327-", - "A187328-", - "A187329-", - "T187330-", - "T187331-", - "C187332-", - "G187333-", - "A187334-", - "G187335-", - "T187336-", - "A187337-", - "T187338-", - "A187339-", - "G187340-", - "G187341-", - "A187342-", - "A187343-", - "G187344-", - "T187345-", - "A187346-", - "G187347-", - "T187348-", - "A187349-", - "T187350-", - "T187351-", - "A187352-", - "C187353-", - "C187354-", - "A187355-", - "T187356-", - "A187357-", - "T187358-", - "C187359-", - "A187360-", - "A187361-", - "C187362-", - "T187363-", - "T187364-", - "C187365-", - "C187366-", - "G187367-", - "A187368-", - "G187369-", - "T187370-", - "T187371-", - "A187372-", - "A187373-", - "C187374-", - "A187375-", - "A187376-", - "T187377-", - "T187378-", - "A187379-", - "C187380-", - "T187381-", - "C187382-", - "T187383-", - "A187384-", - "A187385-", - "A187386-", - "A187387-", - "C187388-", - "A187389-", - "T187390-", - "G187391-", - "A187392-", - "G187393-", - "G187394-", - "A187395-", - "T187396-", - "T187397-", - "G187398-", - "T187399-", - "A187400-", - "C187401-", - "T187402-", - "C187403-", - "C187404-", - "T187405-", - "G187406-", - "T187407-", - "C187408-", - "T187409-", - "T187410-", - "T187411-", - "A187412-", - "T187413-", - "T187414-", - "G187415-", - "G187416-", - "A187417-", - "G187418-", - "A187419-", - "T187420-", - "C187421-", - "A187422-", - "C187423-", - "T187424-", - "A187425-", - "T187426-", - "T187427-", - "T187428-", - "A187429-", - "G187430-", - "T187431-", - "C187432-", - "G187433-", - "T187434-", - "T187435-", - "G187436-", - "A187437-", - "T187438-", - "A187439-", - "A187440-", - "A187441-", - "C187442-", - "T187443-", - "A187444-", - "G187445-", - "T187446-", - "A187447-", - "A187448-", - "C187449-", - "C187450-", - "T187451-", - "C187452-", - "A187453-", - "G187454-", - "G187455-", - "T187456-", - "T187457-", - "T187458-", - "C187459-", - "T187460-", - "T187461-", - "T187462-", - "A187463-", - "C187464-", - "A187465-", - "A187466-", - "A187467-", - "C187468-", - "G187469-", - "A187470-", - "T187471-", - "A187472-", - "A187473-", - "A187474-", - "G187475-", - "T187476-", - "A187477-", - "C187478-", - "A187479-", - "A187480-", - "C187481-", - "A187482-", - "T187483-", - "C187484-", - "A187485-", - "A187486-", - "G187487-", - "A187488-", - "C187489-", - "C187490-", - "T187491-", - "C187492-", - "A187493-", - "C187494-", - "A187495-", - "A187496-", - "C187497-", - "A187498-", - "C187499-", - "A187500-", - "G187501-", - "T187502-", - "G187503-", - "C187504-", - "A187505-", - "A187506-", - "G187507-", - "A187508-", - "T187509-", - "T187510-", - "A187511-", - "A187512-", - "T187513-", - "C187514-", - "T187515-", - "A187516-", - "G187517-", - "A187518-", - "A187519-", - "A187520-", - "T187521-", - "C187522-", - "A187523-", - "A187524-", - "A187525-", - "T187526-", - "G187527-", - "T187528-", - "A187529-", - "A187530-", - "T187531-", - "T187532-", - "C187533-", - "T187534-", - "G187535-", - "G187536-", - "A187537-", - "G187538-", - "G187539-", - "A187540-", - "G187541-", - "A187542-", - "A187543-", - "T187544-", - "C187545-", - "T187546-", - "A187547-", - "G187548-", - "A187549-", - "C187550-", - "A187551-", - "A187552-", - "C187553-", - "T187554-", - "A187555-", - "A187556-", - "C187557-", - "A187558-", - "C187559-", - "C187560-", - "C187561-", - "A187562-", - "C187563-", - "G187564-", - "G187565-", - "C187566-", - "G187567-", - "A187568-", - "A187569-", - "G187570-", - "T187571-", - "A187572-", - "T187573-", - "A187574-", - "C187575-", - "T187576-", - "T187577-", - "T187578-", - "A187579-", - "T187580-", - "G187581-", - "C187582-", - "C187583-", - "T187584-", - "C187585-", - "A187586-", - "T187587-", - "T187588-", - "C187589-", - "A187590-", - "G187591-", - "A187592-", - "A187593-", - "A187594-", - "C187595-", - "G187596-", - "G187597-", - "T187598-", - "A187599-", - "A187600-", - "C187601-", - "T187602-", - "G187603-", - "T187604-", - "A187605-", - "G187606-", - "T187607-", - "A187608-", - "G187609-", - "G187610-", - "A187611-", - "G187612-", - "A187613-", - "C187614-", - "T187615-", - "G187616-", - "T187617-", - "C187618-", - "T187619-", - "C187620-", - "T187621-", - "C187622-", - "T187623-", - "A187624-", - "A187625-", - "T187626-", - "C187627-", - "T187628-", - "C187629-", - "G187630-", - "A187631-", - "T187632-", - "G187633-", - "T187634-", - "A187635-", - "T187636-", - "A187637-", - "T187638-", - "A187639-", - "T187640-", - "A187641-", - "A187642-", - "T187643-", - "A187644-", - "T187645-", - "A187646-", - "T187647-", - "A187648-", - "C187649-", - "C187650-", - "A187651-", - "A187652-", - "T187653-", - "A187654-", - "C187655-", - "G187656-", - "G187657-", - "A187658-", - "C187659-", - "G187660-", - "C187661-", - "G187662-", - "A187663-", - "T187664-", - "A187665-", - "T187666-", - "A187667-", - "T187668-", - "T187669-", - "C187670-", - "C187671-", - "G187672-", - "A187673-", - "C187674-", - "A187675-", - "T187676-", - "G187677-", - "A187678-", - "A187679-", - "T187680-", - "G187681-", - "G187682-", - "C187683-", - "G187684-", - "T187685-", - "C187686-", - "G187687-", - "C187688-", - "T187689-", - "T187690-", - "A187691-", - "T187692-", - "C187693-", - "A187694-", - "T187695-", - "A187696-", - "T187697-", - "G187698-", - "T187699-", - "T187700-", - "A187701-", - "T187702-", - "A187703-", - "T187704-", - "C187705-", - "C187706-", - "T187707-", - "A187708-", - "A187709-", - "A187710-", - "T187711-", - "G187712-", - "T187713-", - "T187714-", - "G187715-", - "A187716-", - "T187717-", - "C187718-", - "A187719-", - "T187720-", - "A187721-", - "T187722-", - "T187723-", - "C187724-", - "C187725-", - "A187726-", - "C187727-", - "A187728-", - "A187729-", - "A187730-", - "T187731-", - "G187732-", - "A187733-", - "T187734-", - "T187735-", - "G187736-", - "T187737-", - "G187738-", - "A187739-", - "A187740-", - "C187741-", - "G187742-", - "A187743-", - "G187744-", - "A187745-", - "T187746-", - "T187747-", - "A187748-", - "A187749-", - "A187750-", - "T187751-", - "C187752-", - "A187753-", - "T187754-", - "C187755-", - "T187756-", - "A187757-", - "A187758-", - "C187759-", - "A187760-", - "A187761-", - "A187762-", - "T187763-", - "A187764-", - "A187765-", - "T187766-", - "T187767-", - "A187768-", - "G187769-", - "T187770-", - "T187771-", - "T187772-", - "T187773-", - "T187774-", - "T187775-", - "A187776-", - "T187777-", - "G187778-", - "A187779-", - "C187780-", - "A187781-", - "T187782-", - "T187783-", - "A187784-", - "A187785-", - "C187786-", - "A187787-", - "T187788-", - "A187789-", - "T187790-", - "A187791-", - "A187792-", - "T187793-", - "A187794-", - "A187795-", - "A187796-", - "T187797-", - "A187798-", - "A187799-", - "A187800-", - "T187801-", - "T187802-", - "A187803-", - "A187804-", - "T187805-", - "C187806-", - "A187807-", - "T187808-", - "T187809-", - "A187810-", - "T187811-", - "T187812-", - "G187813-", - "A187814-", - "C187815-", - "T187816-", - "T187817-", - "A187818-", - "A187819-", - "C187820-", - "G187821-", - "A187822-", - "T187823-", - "G187824-", - "A187825-", - "C187826-", - "G187827-", - "A187828-", - "A187829-", - "A187830-", - "G187831-", - "T187832-", - "T187833-", - "A187834-", - "T187835-", - "C187836-", - "A187837-", - "T187838-", - "T187839-", - "A187840-", - "T187841-", - "C187842-", - "T187843-", - "T187844-", - "A187845-", - "G187846-", - "G187847-", - "A187848-", - "T187849-", - "T187850-", - "C187851-", - "T187852-", - "T187853-", - "G187854-", - "A187855-", - "T187856-", - "T187857-", - "A187858-", - "T187859-", - "T187860-", - "A187861-", - "A187862-", - "T187863-", - "A187864-", - "C187865-", - "A187866-", - "A187867-", - "A187868-", - "T187869-", - "T187870-", - "C187871-", - "G187872-", - "T187873-", - "T187874-", - "G187875-", - "T187876-", - "G187877-", - "T187878-", - "C187879-", - "T187880-", - "A187881-", - "T187882-", - "G187883-", - "A187884-", - "A187885-", - "A187886-", - "T187887-", - "G187888-", - "T187889-", - "G187890-", - "A187891-", - "A187892-", - "C187893-", - "A187894-", - "A187895-", - "G187896-", - "G187897-", - "T187898-", - "G187899-", - "T187900-", - "C187901-", - "T187902-", - "C187903-", - "A187904-", - "T187905-", - "A187906-", - "T187907-", - "T187908-", - "A187909-", - "T187910-", - "A187911-", - "A187912-", - "T187913-", - "G187914-", - "C187915-", - "A187916-", - "C187917-", - "A187918-", - "A187919-", - "G187920-", - "A187921-", - "A187922-", - "T187923-", - "T187924-", - "A187925-", - "A187926-", - "A187927-", - "G187928-", - "T187929-", - "G187930-", - "T187931-", - "T187932-", - "G187933-", - "T187934-", - "A187935-", - "A187936-", - "A187937-", - "C187938-", - "T187939-", - "A187940-", - "T187941-", - "C187942-", - "T187943-", - "A187944-", - "G187945-", - "C187946-", - "C187947-", - "A187948-", - "G187949-", - "G187950-", - "A187951-", - "A187952-", - "C187953-", - "A187954-", - "T187955-", - "A187956-", - "T187957-", - "T187958-", - "C187959-", - "A187960-", - "G187961-", - "A187962-", - "T187963-", - "T187964-", - "A187965-", - "T187966-", - "C187967-", - "G187968-", - "A187969-", - "T187970-", - "G187971-", - "T187972-", - "G187973-", - "A187974-", - "T187975-", - "A187976-", - "A187977-", - "A187978-", - "T187979-", - "A187980-", - "C187981-", - "A187982-", - "G187983-", - "C187984-", - "G187985-", - "A187986-", - "T187987-", - "A187988-", - "C187989-", - "C187990-", - "A187991-", - "T187992-", - "C187993-", - "T187994-", - "G187995-", - "T187996-", - "G187997-", - "G187998-", - "A187999-", - "C188000-", - "A188001-", - "T188002-", - "T188003-", - "G188004-", - "T188005-", - "C188006-", - "C188007-", - "A188008-", - "A188009-", - "G188010-", - "T188011-", - "G188012-", - "A188013-", - "C188014-", - "A188015-", - "C188016-", - "A188017-", - "T188018-", - "T188019-", - "C188020-", - "A188021-", - "C188022-", - "G188023-", - "T188024-", - "C188025-", - "A188026-", - "A188027-", - "T188028-", - "A188029-", - "T188030-", - "A188031-", - "T188032-", - "A188033-", - "A188034-", - "T188035-", - "C188036-", - "G188037-", - "T188038-", - "T188039-", - "C188040-", - "T188041-", - "C188042-", - "C188043-", - "T188044-", - "C188045-", - "G188046-", - "G188047-", - "T188048-", - "G188049-", - "T188050-", - "C188051-", - "A188052-", - "T188053-", - "A188054-", - "G188055-", - "T188056-", - "T188057-", - "G188058-", - "T188059-", - "A188060-", - "G188061-", - "A188062-", - "G188063-", - "G188064-", - "T188065-", - "C188066-", - "A188067-", - "C188068-", - "A188069-", - "C188070-", - "C188071-", - "T188072-", - "T188073-", - "G188074-", - "T188075-", - "A188076-", - "C188077-", - "A188078-", - "C188079-", - "C188080-", - "T188081-", - "A188082-", - "C188083-", - "C188084-", - "A188085-", - "C188086-", - "A188087-", - "A188088-", - "A188089-", - "T188090-", - "A188091-", - "G188092-", - "A188093-", - "A188094-", - "T188095-", - "A188096-", - "T188097-", - "G188098-", - "T188099-", - "C188100-", - "A188101-", - "T188102-", - "T188103-", - "G188104-", - "T188105-", - "G188106-", - "A188107-", - "C188108-", - "T188109-", - "C188110-", - "G188111-", - "A188112-", - "A188113-", - "T188114-", - "A188115-", - "G188116-", - "T188117-", - "T188118-", - "A188119-", - "T188120-", - "C188121-", - "G188122-", - "T188123-", - "C188124-", - "T188125-", - "C188126-", - "C188127-", - "T188128-", - "T188129-", - "A188130-", - "A188131-", - "A188132-", - "G188133-", - "C188134-", - "T188135-", - "T188136-", - "C188137-", - "T188138-", - "G188139-", - "A188140-", - "T188141-", - "G188142-", - "G188143-", - "T188144-", - "A188145-", - "A188146-", - "C188147-", - "T188148-", - "G188149-", - "T188150-", - "G188151-", - "T188152-", - "T188153-", - "A188154-", - "C188155-", - "A188156-", - "T188157-", - "G188158-", - "T188159-", - "G188160-", - "C188161-", - "T188162-", - "C188163-", - "C188164-", - "T188165-", - "A188166-", - "A188167-", - "A188168-", - "A188169-", - "C188170-", - "A188171-", - "A188172-", - "A188173-", - "A188174-", - "T188175-", - "A188176-", - "T188177-", - "G188178-", - "G188179-", - "T188180-", - "C188181-", - "G188182-", - "T188183-", - "G188184-", - "T188185-", - "G188186-", - "T188187-", - "A188188-", - "C188189-", - "G188190-", - "G188191-", - "A188192-", - "A188193-", - "A188194-", - "G188195-", - "A188196-", - "A188197-", - "A188198-", - "G188199-", - "G188200-", - "A188201-", - "G188202-", - "A188203-", - "A188204-", - "A188205-", - "A188206-", - "T188207-", - "G188208-", - "A188209-", - "T188210-", - "A188211-", - "T188212-", - "G188213-", - "G188214-", - "A188215-", - "A188216-", - "T188217-", - "A188218-", - "C188219-", - "C188220-", - "A188221-", - "T188222-", - "T188223-", - "T188224-", - "G188225-", - "T188226-", - "A188227-", - "A188228-", - "G188229-", - "A188230-", - "A188231-", - "A188232-", - "T188233-", - "G188234-", - "T188235-", - "C188236-", - "G188237-", - "G188238-", - "A188239-", - "A188240-", - "G188241-", - "G188242-", - "G188243-", - "T188244-", - "A188245-", - "C188246-", - "T188247-", - "T188248-", - "A188249-", - "T188250-", - "T188251-", - "C188252-", - "A188253-", - "G188254-", - "A188255-", - "T188256-", - "A188257-", - "T188258-", - "T188259-", - "G188260-", - "T188261-", - "A188262-", - "T188263-", - "C188264-", - "T188265-", - "G188266-", - "A188267-", - "C188268-", - "T188269-", - "C188270-", - "T188271-", - "G188272-", - "A188273-", - "T188274-", - "C188275-", - "A188276-", - "A188277-", - "T188278-", - "G188279-", - "T188280-", - "A188281-", - "A188282-", - "A188283-", - "C188284-", - "C188285-", - "T188286-", - "A188287-", - "T188288-", - "G188289-", - "A188290-", - "C188291-", - "A188292-", - "A188293-", - "G188294-", - "A188295-", - "T188296-", - "A188297-", - "A188298-", - "G188299-", - "A188300-", - "C188301-", - "T188302-", - "T188303-", - "A188304-", - "C188305-", - "T188306-", - "C188307-", - "G188308-", - "C188309-", - "A188310-", - "T188311-", - "C188312-", - "T188313-", - "A188314-", - "C188315-", - "T188316-", - "G188317-", - "G188318-", - "A188319-", - "T188320-", - "A188321-", - "G188322-", - "A188323-", - "C188324-", - "A188325-", - "T188326-", - "A188327-", - "A188328-", - "A188329-", - "T188330-", - "A188331-", - "T188332-", - "C188333-", - "C188334-", - "T188335-", - "C188336-", - "C188337-", - "T188338-", - "C188339-", - "G188340-", - "T188341-", - "A188342-", - "A188343-", - "T188344-", - "A188345-", - "A188346-", - "T188347-", - "G188348-", - "A188349-", - "A188350-", - "A188351-", - "T188352-", - "A188353-", - "T188354-", - "A188355-", - "A188356-", - "T188357-", - "A188358-", - "T188359-", - "A188360-", - "C188361-", - "A188362-", - "C188363-", - "T188364-", - "A188365-", - "A188366-", - "T188367-", - "T188368-", - "A188369-", - "T188370-", - "T188371-", - "A188372-", - "A188373-", - "T188374-", - "A188375-", - "T188376-", - "C188377-", - "A188378-", - "A188379-", - "T188380-", - "C188381-", - "G188382-", - "A188383-", - "G188384-", - "T188385-", - "A188386-", - "T188387-", - "T188388-", - "A188389-", - "A188390-", - "C188391-", - "A188392-", - "T188393-", - "A188394-", - "T188395-", - "A188396-", - "A188397-", - "G188398-", - "T188399-", - "T188400-", - "A188401-", - "T188402-", - "T188403-", - "T188404-", - "T188405-", - "T188406-", - "A188407-", - "A188408-", - "A188409-", - "C188410-", - "C188411-", - "C188412-", - "C188413-", - "T188414-", - "T188415-", - "T188416-", - "T188417-", - "G188418-", - "G188419-", - "G188420-", - "T188421-", - "T188422-", - "C188423-", - "C188424-", - "G188425-", - "T188426-", - "C188427-", - "C188428-", - "T188429-", - "A188430-", - "A188431-", - "A188432-", - "C188433-", - "G188434-", - "G188435-", - "C188436-", - "G188437-", - "T188438-", - "T188439-", - "T188440-", - "C188441-", - "G188442-", - "G188443-", - "T188444-", - "C188445-", - "T188446-", - "G188447-", - "T188448-", - "G188449-", - "T188450-", - "C188451-", - "G188452-", - "C188453-", - "C188454-", - "A188455-", - "C188456-", - "C188457-", - "A188458-", - "T188459-", - "G188460-", - "G188461-", - "T188462-", - "C188463-", - "A188464-", - "C188465-", - "A188466-", - "C188467-", - "C188468-", - "G188469-", - "A188470-", - "G188471-", - "C188472-", - "C188473-", - "T188474-", - "C188475-", - "T188476-", - "G188477-", - "C188478-", - "G188479-", - "T188480-", - "G188481-", - "C188482-", - "T188483-", - "C188484-", - "C188485-", - "T188486-", - "C188487-", - "C188488-", - "A188489-", - "T188490-", - "C188491-", - "G188492-", - "A188493-", - "G188494-", - "G188495-", - "A188496-", - "C188497-", - "G188498-", - "A188499-", - "C188500-", - "T188501-", - "T188502-", - "C188503-", - "A188504-", - "A188505-", - "C188506-", - "T188507-", - "A188508-", - "T188509-", - "G188510-", - "A188511-", - "C188512-", - "A188513-", - "G188514-", - "C188515-", - "T188516-", - "C188517-", - "G188518-", - "G188519-", - "T188520-", - "G188521-", - "G188522-", - "C188523-", - "G188524-", - "T188525-", - "C188526-", - "T188527-", - "G188528-", - "C188529-", - "C188530-", - "A188531-", - "G188532-", - "C188533-", - "G188534-", - "T188535-", - "G188536-", - "T188537-", - "A188538-", - "C188539-", - "A188540-", - "T188541-", - "A188542-", - "C188543-", - "G188544-", - "A188545-", - "A188546-", - "T188547-", - "G188548-", - "G188549-", - "C188550-", - "A188551-", - "T188552-", - "T188553-", - "T188554-", - "C188555-", - "T188556-", - "A188557-", - "A188558-", - "G188559-", - "A188560-", - "A188561-", - "A188562-", - "A188563-", - "G188564-", - "T188565-", - "C188566-", - "T188567-", - "A188568-", - "C188569-", - "G188570-", - "G188571-", - "T188572-", - "A188573-", - "T188574-", - "C188575-", - "C188576-", - "T188577-", - "T188578-", - "T188579-", - "C188580-", - "T188581-", - "A188582-", - "C188583-", - "A188584-", - "A188585-", - "T188586-", - "T188587-", - "T188588-", - "C188589-", - "C188590-", - "T188591-", - "T188592-", - "T188593-", - "A188594-", - "A188595-", - "C188596-", - "A188597-", - "A188598-", - "C188599-", - "G188600-", - "G188601-", - "C188602-", - "A188603-", - "A188604-", - "C188605-", - "A188606-", - "G188607-", - "C188608-", - "T188609-", - "G188610-", - "C188611-", - "A188612-", - "G188613-", - "T188614-", - "A188615-", - "T188616-", - "T188617-", - "T188618-", - "T188619-", - "T188620-", - "A188621-", - "T188622-", - "A188623-", - "C188624-", - "T188625-", - "T188626-", - "T188627-", - "G188628-", - "A188629-", - "A188630-", - "T188631-", - "G188632-", - "C188633-", - "A188634-", - "T188635-", - "C188636-", - "G188637-", - "G188638-", - "A188639-", - "C188640-", - "A188641-", - "T188642-", - "T188643-", - "T188644-", - "A188645-", - "T188646-", - "A188647-", - "C188648-", - "A188649-", - "A188650-", - "G188651-", - "G188652-", - "G188653-", - "A188654-", - "G188655-", - "T188656-", - "C188657-", - "C188658-", - "T188659-", - "G188660-", - "T188661-", - "T188662-", - "C188663-", - "T188664-", - "A188665-", - "A188666-", - "T188667-", - "A188668-", - "T188669-", - "T188670-", - "G188671-", - "G188672-", - "C188673-", - "A188674-", - "T188675-", - "C188676-", - "A188677-", - "A188678-", - "T188679-", - "G188680-", - "T188681-", - "T188682-", - "C188683-", - "G188684-", - "G188685-", - "A188686-", - "T188687-", - "C188688-", - "T188689-", - "A188690-", - "T188691-", - "A188692-", - "G188693-", - "G188694-", - "C188695-", - "T188696-", - "T188697-", - "G188698-", - "A188699-", - "T188700-", - "T188701-", - "T188702-", - "T188703-", - "C188704-", - "G188705-", - "C188706-", - "A188707-", - "T188708-", - "T188709-", - "G188710-", - "A188711-", - "C188712-", - "T188713-", - "T188714-", - "T188715-", - "A188716-", - "C188717-", - "A188718-", - "C188719-", - "A188720-", - "G188721-", - "A188722-", - "C188723-", - "A188724-", - "T188725-", - "G188726-", - "A188727-", - "A188728-", - "C188729-", - "A188730-", - "T188731-", - "C188732-", - "C188733-", - "C188734-", - "C188735-", - "T188736-", - "G188737-", - "A188738-", - "A188739-", - "T188740-", - "C188741-", - "T188742-", - "G188743-", - "T188744-", - "A188745-", - "C188746-", - "A188747-", - "T188748-", - "A188749-", - "C188750-", - "T188751-", - "T188752-", - "T188753-", - "G188754-", - "T188755-", - "G188756-", - "G188757-", - "A188758-", - "T188759-", - "T188760-", - "T188761-", - "A188762-", - "C188763-", - "A188764-", - "C188765-", - "T188766-", - "G188767-", - "T188768-", - "T188769-", - "A188770-", - "G188771-", - "A188772-", - "A188773-", - "T188774-", - "C188775-", - "T188776-", - "C188777-", - "T188778-", - "A188779-", - "A188780-", - "C188781-", - "G188782-", - "C188783-", - "T188784-", - "G188785-", - "G188786-", - "C188787-", - "C188788-", - "T188789-", - "C188790-", - "T188791-", - "G188792-", - "T188793-", - "T188794-", - "G188795-", - "T188796-", - "T188797-", - "A188798-", - "C188799-", - "T188800-", - "T188801-", - "T188802-", - "C188803-", - "T188804-", - "A188805-", - "T188806-", - "G188807-", - "A188808-", - "T188809-", - "G188810-", - "C188811-", - "A188812-", - "C188813-", - "G188814-", - "T188815-", - "A188816-", - "T188817-", - "C188818-", - "G188819-", - "T188820-", - "T188821-", - "A188822-", - "T188823-", - "G188824-", - "C188825-", - "A188826-", - "A188827-", - "G188828-", - "C188829-", - "T188830-", - "T188831-", - "T188832-", - "C188833-", - "A188834-", - "T188835-", - "G188836-", - "T188837-", - "T188838-", - "G188839-", - "A188840-", - "C188841-", - "T188842-", - "A188843-", - "C188844-", - "T188845-", - "G188846-", - "C188847-", - "A188848-", - "G188849-", - "T188850-", - "G188851-", - "T188852-", - "T188853-", - "T188854-", - "C188855-", - "T188856-", - "T188857-", - "G188858-", - "C188859-", - "T188860-", - "C188861-", - "T188862-", - "G188863-", - "A188864-", - "C188865-", - "T188866-", - "A188867-", - "C188868-", - "A188869-", - "T188870-", - "A188871-", - "T188872-", - "A188873-", - "C188874-", - "T188875-", - "C188876-", - "T188877-", - "A188878-", - "C188879-", - "A188880-", - "A188881-", - "T188882-", - "C188883-", - "A188884-", - "A188885-", - "A188886-", - "G188887-", - "A188888-", - "G188889-", - "A188890-", - "G188891-", - "A188892-", - "T188893-", - "T188894-", - "T188895-", - "C188896-", - "A188897-", - "G188898-", - "T188899-", - "A188900-", - "A188901-", - "A188902-", - "C188903-", - "T188904-", - "T188905-", - "G188906-", - "T188907-", - "A188908-", - "A188909-", - "C188910-", - "A188911-", - "G188912-", - "G188913-", - "A188914-", - "T188915-", - "T188916-", - "G188917-", - "T188918-", - "T188919-", - "T188920-", - "G188921-", - "C188922-", - "T188923-", - "G188924-", - "C188925-", - "T188926-", - "T188927-", - "T188928-", - "C188929-", - "T188930-", - "G188931-", - "G188932-", - "-196602A" - ], - "OPG015": [ - "M1-", - "E2-", - "S3-", - "V4-", - "D5-", - "F6-", - "M7-", - "A8-", - "V9-", - "D10-", - "E11-", - "Q12-", - "F13-", - "H14-", - "D15-", - "D16-", - "L17-", - "D18-", - "L19-", - "W20-", - "S21-", - "L22-", - "S23-", - "L24-", - "V25-", - "D26-", - "D27-", - "Y28-", - "K29-", - "K30-", - "H31-", - "G32-", - "L33-", - "G34-", - "V35-", - "D36-", - "C37-", - "Y38-", - "V39-", - "L40-", - "E41-", - "P42-", - "V43-", - "V44-", - "D45-", - "R46-", - "K47-", - "I48-", - "F49-", - "D50-", - "R51-", - "F52-", - "L53-", - "L54-", - "E55-", - "P56-", - "I57-", - "C58-", - "D59-", - "P60-", - "V61-", - "D62-", - "V63-", - "L64-", - "Y65-", - "D66-", - "Y67-", - "F68-", - "R69-", - "I70-", - "H71-", - "R72-", - "D73-", - "N74-", - "I75-", - "D76-", - "Q77-", - "Y78-", - "I79-", - "V80-", - "D81-", - "R82-", - "L83-", - "F84-", - "A85-", - "Y86-", - "I87-", - "T88-", - "Y89-", - "K90-", - "D91-", - "I92-", - "I93-", - "S94-", - "A95-", - "L96-", - "V97-", - "S98-", - "K99-", - "N100-", - "Y101-", - "M102-", - "E103-", - "D104-", - "I105-", - "F106-", - "S107-", - "I108-", - "I109-", - "I110-", - "K111-", - "N112-", - "C113-", - "N114-", - "S115-", - "V116-", - "Q117-", - "D118-", - "L119-", - "L120-", - "L121-", - "Y122-", - "Y123-", - "L124-", - "S125-", - "N126-", - "A127-", - "Y128-", - "V129-", - "E130-", - "I131-", - "D132-", - "I133-", - "V134-", - "D135-", - "L136-", - "M137-", - "V138-", - "D139-", - "H140-", - "G141-", - "A142-", - "V143-", - "I144-", - "Y145-", - "K146-", - "I147-", - "E148-", - "C149-", - "L150-", - "N151-", - "A152-", - "Y153-", - "F154-", - "R155-", - "G156-", - "I157-", - "C158-", - "K159-", - "K160-", - "E161-", - "S162-", - "S163-", - "V164-", - "V165-", - "E166-", - "F167-", - "I168-", - "L169-", - "N170-", - "C171-", - "G172-", - "I173-", - "P174-", - "D175-", - "E176-", - "N177-", - "D178-", - "V179-", - "K180-", - "L181-", - "D182-", - "L183-", - "Y184-", - "K185-", - "I186-", - "I187-", - "Q188-", - "Y189-", - "T190-", - "R191-", - "G192-", - "F193-", - "L194-", - "V195-", - "D196-", - "E197-", - "P198-", - "T199-", - "V200-", - "L201-", - "E202-", - "I203-", - "Y204-", - "K205-", - "L206-", - "C207-", - "I208-", - "P209-", - "Y210-", - "I211-", - "E212-", - "D213-", - "I214-", - "N215-", - "Q216-", - "L217-", - "D218-", - "A219-", - "G220-", - "G221-", - "R222-", - "T223-", - "L224-", - "L225-", - "Y226-", - "R227-", - "A228-", - "I229-", - "Y230-", - "A231-", - "G232-", - "Y233-", - "I234-", - "D235-", - "L236-", - "V237-", - "S238-", - "W239-", - "L240-", - "L241-", - "E242-", - "N243-", - "G244-", - "A245-", - "N246-", - "V247-", - "N248-", - "A249-", - "V250-", - "M251-", - "S252-", - "N253-", - "G254-", - "Y255-", - "T256-", - "C257-", - "L258-", - "D259-", - "V260-", - "A261-", - "V262-", - "D263-", - "R264-", - "G265-", - "S266-", - "V267-", - "I268-", - "A269-", - "R270-", - "R271-", - "E272-", - "A273-", - "H274-", - "L275-", - "K276-", - "I277-", - "L278-", - "E279-", - "I280-", - "L281-", - "L282-", - "R283-", - "E284-", - "P285-", - "L286-", - "S287-", - "I288-", - "D289-", - "C290-", - "I291-", - "K292-", - "L293-", - "A294-", - "I295-", - "L296-", - "N297-", - "N298-", - "T299-", - "I300-", - "E301-", - "N302-", - "H303-", - "D304-", - "V305-", - "I306-", - "K307-", - "L308-", - "C309-", - "I310-", - "K311-", - "Y312-", - "F313-", - "M314-", - "M315-", - "V316-", - "D317-", - "Y318-", - "S319-", - "L320-", - "C321-", - "N322-", - "V323-", - "Y324-", - "A325-", - "S326-", - "S327-", - "L328-", - "F329-", - "D330-", - "Y331-", - "I332-", - "I333-", - "D334-", - "C335-", - "K336-", - "Q337-", - "E338-", - "L339-", - "E340-", - "Y341-", - "I342-", - "R343-", - "Q344-", - "M345-", - "K346-", - "I347-", - "H348-", - "N349-", - "T350-", - "T351-", - "M352-", - "Y353-", - "E354-", - "L355-", - "I356-", - "Y357-", - "N358-", - "R359-", - "D360-", - "K361-", - "N362-", - "K363-", - "H364-", - "A365-", - "S366-", - "H367-", - "I368-", - "L369-", - "H370-", - "R371-", - "Y372-", - "S373-", - "K374-", - "H375-", - "P376-", - "V377-", - "L378-", - "T379-", - "Q380-", - "C381-", - "I382-", - "T383-", - "K384-", - "G385-", - "F386-", - "K387-", - "I388-", - "Y389-", - "T390-", - "E391-", - "V392-", - "T393-", - "E394-", - "Q395-", - "V396-", - "T397-", - "K398-", - "A399-", - "L400-", - "N401-", - "R402-", - "R403-", - "A404-", - "L405-", - "I406-", - "D407-", - "E408-", - "I409-", - "I410-", - "N411-", - "N412-", - "V413-", - "S414-", - "T415-", - "D416-", - "D417-", - "N418-", - "L419-", - "L420-", - "S421-", - "K422-", - "L423-", - "P424-", - "L425-", - "E426-", - "I427-", - "R428-", - "D429-", - "L430-", - "I431-", - "V432-", - "S433-", - "Q434-", - "A435-", - "V436-", - "I437-", - "*438-" - ], - "OPG019": [ - "M1-", - "S2-", - "I3-", - "K4-", - "Y5-", - "L6-", - "M7-", - "L8-", - "L9-", - "F10-", - "A11-", - "A12-", - "M13-", - "I14-", - "I15-", - "R16-", - "S17-", - "L18-", - "A19-", - "D20-", - "S21-", - "G22-", - "N23-", - "A24-", - "I25-", - "E26-", - "T27-", - "T28-", - "S29-", - "P30-", - "E31-", - "I32-", - "T33-", - "N34-", - "A35-", - "T36-", - "T37-", - "D38-", - "I39-", - "P40-", - "A41-", - "I42-", - "R43-", - "L44-", - "C45-", - "G46-", - "P47-", - "E48-", - "G49-", - "D50-", - "G51-", - "Y52-", - "C53-", - "L54-", - "H55-", - "G56-", - "D57-", - "C58-", - "I59-", - "H60-", - "A61-", - "R62-", - "D63-", - "I64-", - "D65-", - "G66-", - "M67-", - "Y68-", - "C69-", - "R70-", - "C71-", - "S72-", - "H73-", - "G74-", - "Y75-", - "T76-", - "G77-", - "I78-", - "R79-", - "C80-", - "Q81-", - "H82-", - "V83-", - "V84-", - "L85-", - "V86-", - "D87-", - "Y88-", - "Q89-", - "R90-", - "S91-", - "G92-", - "K93-", - "P94-", - "D95-", - "T96-", - "T97-", - "T98-", - "S99-", - "Y100-", - "I101-", - "P102-", - "S103-", - "L104-", - "G105-", - "I106-", - "V107-", - "L108-", - "V109-", - "L110-", - "V111-", - "G112-", - "I113-", - "I114-", - "I115-", - "T116-", - "C117-", - "C118-", - "L119-", - "L120-", - "S121-", - "V122-", - "Y123-", - "M124-", - "F125-", - "T126-", - "R127-", - "R128-", - "T129-", - "K130-", - "L131-", - "P132-", - "I133-", - "Q134-", - "D135-", - "M136-", - "V137-", - "V138-", - "L139-", - "Y140-", - "F141-", - "L142-", - "*143-" - ], - "OPG021": [ - "M1-", - "E2-", - "F3-", - "D4-", - "P5-", - "V6-", - "K7-", - "I8-", - "N9-", - "T10-", - "S11-", - "S12-", - "I13-", - "D14-", - "H15-", - "V16-", - "T17-", - "I18-", - "L19-", - "Q20-", - "Y21-", - "I22-", - "D23-", - "E24-", - "P25-", - "N26-", - "D27-", - "I28-", - "R29-", - "L30-", - "T31-", - "V32-", - "C33-", - "I34-", - "I35-", - "R36-", - "N37-", - "V38-", - "N39-", - "N40-", - "I41-", - "T42-", - "Y43-", - "Y44-", - "I45-", - "N46-", - "I47-", - "T48-", - "K49-", - "I50-", - "N51-", - "P52-", - "H53-", - "L54-", - "A55-", - "N56-", - "R57-", - "F58-", - "R59-", - "A60-", - "W61-", - "K62-", - "K63-", - "R64-", - "I65-", - "A66-", - "G67-", - "R68-", - "D69-", - "Y70-", - "M71-", - "T72-", - "N73-", - "L74-", - "S75-", - "R76-", - "D77-", - "T78-", - "G79-", - "I80-", - "Q81-", - "Q82-", - "S83-", - "K84-", - "L85-", - "T86-", - "E87-", - "T88-", - "I89-", - "R90-", - "N91-", - "C92-", - "Q93-", - "K94-", - "N95-", - "K96-", - "N97-", - "I98-", - "Y99-", - "G100-", - "L101-", - "Y102-", - "I103-", - "H104-", - "Y105-", - "N106-", - "L107-", - "V108-", - "I109-", - "N110-", - "V111-", - "V112-", - "I113-", - "D114-", - "W115-", - "I116-", - "T117-", - "D118-", - "V119-", - "I120-", - "V121-", - "Q122-", - "S123-", - "I124-", - "L125-", - "R126-", - "G127-", - "L128-", - "V129-", - "N130-", - "W131-", - "Y132-", - "I133-", - "A134-", - "N135-", - "N136-", - "T137-", - "Y138-", - "T139-", - "P140-", - "N141-", - "T142-", - "P143-", - "N144-", - "N145-", - "T146-", - "T147-", - "T148-", - "I149-", - "S150-", - "E151-", - "L152-", - "D153-", - "I154-", - "I155-", - "K156-", - "I157-", - "L158-", - "D159-", - "K160-", - "Y161-", - "E162-", - "D163-", - "M164-", - "Y165-", - "R166-", - "V167-", - "S168-", - "K169-", - "E170-", - "K171-", - "E172-", - "C173-", - "G174-", - "I175-", - "C176-", - "Y177-", - "E178-", - "V179-", - "V180-", - "Y181-", - "S182-", - "K183-", - "R184-", - "L185-", - "E186-", - "N187-", - "D188-", - "R189-", - "Y190-", - "F191-", - "G192-", - "L193-", - "L194-", - "D195-", - "S196-", - "C197-", - "N198-", - "H199-", - "I200-", - "F201-", - "C202-", - "I203-", - "T204-", - "C205-", - "I206-", - "N207-", - "I208-", - "W209-", - "H210-", - "R211-", - "T212-", - "R213-", - "R214-", - "E215-", - "T216-", - "G217-", - "A218-", - "S219-", - "D220-", - "N221-", - "C222-", - "P223-", - "I224-", - "C225-", - "R226-", - "T227-", - "R228-", - "F229-", - "K230-", - "K231-", - "I232-", - "T233-", - "M234-", - "S235-", - "K236-", - "F237-", - "Y238-", - "K239-", - "L240-", - "V241-", - "N242-", - "*243-" - ], - "OPG022": [ - "M1-", - "R2-", - "I3-", - "L4-", - "F5-", - "L6-", - "I7-", - "A8-", - "F9-", - "M10-", - "Y11-", - "G12-", - "C13-", - "V14-", - "H15-", - "S16-", - "Y17-", - "V18-", - "N19-", - "A20-", - "V21-", - "E22-", - "T23-", - "K24-", - "C25-", - "P26-", - "N27-", - "L28-", - "A29-", - "I30-", - "V31-", - "T32-", - "S33-", - "S34-", - "G35-", - "E36-", - "F37-", - "H38-", - "C39-", - "S40-", - "G41-", - "C42-", - "V43-", - "E44-", - "R45-", - "M46-", - "P47-", - "G48-", - "F49-", - "S50-", - "Y51-", - "M52-", - "Y53-", - "W54-", - "L55-", - "A56-", - "N57-", - "D58-", - "M59-", - "K60-", - "S61-", - "D62-", - "E63-", - "D64-", - "T65-", - "K66-", - "F67-", - "I68-", - "E69-", - "H70-", - "L71-", - "G72-", - "G73-", - "G74-", - "I75-", - "K76-", - "E77-", - "D78-", - "E79-", - "T80-", - "V81-", - "R82-", - "T83-", - "T84-", - "D85-", - "G86-", - "G87-", - "I88-", - "T89-", - "T90-", - "L91-", - "R92-", - "K93-", - "V94-", - "L95-", - "H96-", - "V97-", - "T98-", - "D99-", - "T100-", - "N101-", - "K102-", - "F103-", - "A104-", - "H105-", - "Y106-", - "R107-", - "F108-", - "T109-", - "C110-", - "V111-", - "L112-", - "I113-", - "T114-", - "L115-", - "D116-", - "G117-", - "V118-", - "S119-", - "K120-", - "K121-", - "N122-", - "I123-", - "W124-", - "L125-", - "K126-", - "*127-" - ], - "OPG023": [ - "D392N", - "G394-", - "E395-", - "I396-", - "P397-", - "I398-", - "G399-", - "H400-", - "L401-", - "C402-", - "E403-", - "S404-", - "N405-", - "Y406-", - "G407-", - "C408-", - "Y409-", - "N410-", - "F411-", - "Y412-", - "T413-", - "Y414-", - "T415-", - "Y416-", - "K417-", - "K418-", - "G419-", - "L420-", - "C421-", - "D422-", - "M423-", - "S424-", - "Y425-", - "V426-", - "C427-", - "P428-", - "I429-", - "L430-", - "S431-", - "T432-", - "I433-", - "N434-", - "I435-", - "C436-", - "L437-", - "P438-", - "Y439-", - "L440-", - "K441-", - "D442-", - "I443-", - "N444-", - "M445-", - "I446-", - "D447-", - "K448-", - "R449-", - "G450-", - "E451-", - "T452-", - "L453-", - "L454-", - "H455-", - "K456-", - "A457-", - "V458-", - "R459-", - "Y460-", - "N461-", - "K462-", - "Q463-", - "S464-", - "L465-", - "V466-", - "S467-", - "L468-", - "L469-", - "L470-", - "E471-", - "S472-", - "G473-", - "S474-", - "D475-", - "V476-", - "N477-", - "I478-", - "R479-", - "S480-", - "N481-", - "N482-", - "G483-", - "Y484-", - "T485-", - "C486-", - "I487-", - "T488-", - "I489-", - "A490-", - "I491-", - "N492-", - "E493-", - "S494-", - "R495-", - "N496-", - "I497-", - "E498-", - "L499-", - "L500-", - "K501-", - "M502-", - "L503-", - "L504-", - "C505-", - "H506-", - "K507-", - "P508-", - "T509-", - "L510-", - "D511-", - "C512-", - "V513-", - "I514-", - "D515-", - "S516-", - "L517-", - "S518-", - "E519-", - "V520-", - "S521-", - "N522-", - "I523-", - "V524-", - "D525-", - "N526-", - "A527-", - "Y528-", - "A529-", - "I530-", - "K531-", - "Q532-", - "C533-", - "I534-", - "K535-", - "Y536-", - "T537-", - "M538-", - "I539-", - "I540-", - "D541-", - "D542-", - "C543-", - "T544-", - "S545-", - "S546-", - "K547-", - "I548-", - "P549-", - "E550-", - "S551-", - "I552-", - "S553-", - "Q554-", - "R555-", - "Y556-", - "N557-", - "D558-", - "Y559-", - "I560-", - "D561-", - "L562-", - "C563-", - "N564-", - "Q565-", - "E566-", - "L567-", - "N568-", - "E569-", - "M570-", - "K571-", - "K572-", - "I573-", - "M574-", - "V575-", - "G576-", - "G577-", - "N578-", - "T579-", - "M580-", - "F581-", - "S582-", - "L583-", - "I584-", - "F585-", - "T586-", - "E587-", - "H588-", - "G589-", - "A590-", - "K591-", - "I592-", - "I593-", - "H594-", - "R595-", - "Y596-", - "A597-", - "N598-", - "N599-", - "P600-", - "E601-", - "L602-", - "R603-", - "A604-", - "Y605-", - "Y606-", - "E607-", - "S608-", - "K609-", - "Q610-", - "N611-", - "K612-", - "I613-", - "Y614-", - "V615-", - "E616-", - "A617-", - "Y618-", - "D619-", - "I620-", - "I621-", - "S622-", - "D623-", - "A624-", - "I625-", - "V626-", - "K627-", - "H628-", - "N629-", - "K630-", - "I631-", - "H632-", - "K633-", - "T634-", - "I635-", - "I636-", - "K637-", - "S638-", - "V639-", - "D640-", - "D641-", - "N642-", - "T643-", - "Y644-", - "I645-", - "S646-", - "N647-", - "L648-", - "P649-", - "Y650-", - "T651-", - "I652-", - "K653-", - "Y654-", - "K655-", - "I656-", - "F657-", - "E658-", - "Q659-", - "Q660-", - "*661-" - ], - "OPG057": [ - "E353K" - ], - "OPG210": [ - "N1301X", - "R1302-", - "M1303-", - "F1304-", - "A1305-", - "T1306-", - "L1307-", - "A1308-", - "R1309-", - "G1310-", - "M1311-", - "P1312-", - "F1313-", - "R1314-", - "S1315-", - "T1316-", - "Y1317-", - "C1318-", - "D1319-", - "N1320-", - "R1321-", - "R1322-", - "R1323-", - "S1324-", - "G1325-", - "C1326-", - "Y1327-", - "Y1328-", - "A1329-", - "G1330-", - "I1331-", - "P1332-", - "F1333-", - "H1334-", - "E1335-", - "D1336-", - "S1337-", - "V1338-", - "E1339-", - "T1340-", - "D1341-", - "I1342-", - "H1343-", - "Y1344-", - "G1345-", - "P1346-", - "E1347-", - "I1348-", - "M1349-", - "L1350-", - "K1351-", - "E1352-", - "T1353-", - "Y1354-", - "D1355-", - "I1356-", - "N1357-", - "S1358-", - "I1359-", - "D1360-", - "P1361-", - "R1362-", - "V1363-", - "I1364-", - "T1365-", - "K1366-", - "S1367-", - "K1368-", - "T1369-", - "H1370-", - "F1371-", - "P1372-", - "A1373-", - "P1374-", - "L1375-", - "S1376-", - "V1377-", - "K1378-", - "F1379-", - "M1380-", - "V1381-", - "D1382-", - "N1383-", - "L1384-", - "G1385-", - "N1386-", - "G1387-", - "Y1388-", - "D1389-", - "N1390-", - "P1391-", - "N1392-", - "S1393-", - "F1394-", - "W1395-", - "E1396-", - "D1397-", - "A1398-", - "K1399-", - "T1400-", - "K1401-", - "K1402-", - "R1403-", - "T1404-", - "Y1405-", - "S1406-", - "A1407-", - "M1408-", - "T1409-", - "I1410-", - "K1411-", - "V1412-", - "L1413-", - "P1414-", - "C1415-", - "T1416-", - "V1417-", - "R1418-", - "N1419-", - "K1420-", - "N1421-", - "I1422-", - "D1423-", - "F1424-", - "G1425-", - "Y1426-", - "N1427-", - "Y1428-", - "G1429-", - "D1430-", - "I1431-", - "I1432-", - "S1433-", - "N1434-", - "M1435-", - "V1436-", - "Y1437-", - "L1438-", - "Q1439-", - "S1440-", - "T1441-", - "S1442-", - "Q1443-", - "D1444-", - "Y1445-", - "G1446-", - "D1447-", - "G1448-", - "T1449-", - "K1450-", - "Y1451-", - "T1452-", - "F1453-", - "K1454-", - "S1455-", - "V1456-", - "T1457-", - "R1458-", - "S1459-", - "D1460-", - "H1461-", - "E1462-", - "C1463-", - "E1464-", - "S1465-", - "S1466-", - "L1467-", - "D1468-", - "L1469-", - "T1470-", - "S1471-", - "K1472-", - "E1473-", - "V1474-", - "T1475-", - "V1476-", - "T1477-", - "C1478-", - "P1479-", - "A1480-", - "F1481-", - "S1482-", - "I1483-", - "P1484-", - "R1485-", - "N1486-", - "I1487-", - "S1488-", - "T1489-", - "Y1490-", - "E1491-", - "G1492-", - "L1493-", - "C1494-", - "F1495-", - "S1496-", - "V1497-", - "T1498-", - "T1499-", - "S1500-", - "K1501-", - "D1502-", - "H1503-", - "C1504-", - "A1505-", - "T1506-", - "G1507-", - "I1508-", - "G1509-", - "W1510-", - "L1511-", - "K1512-", - "S1513-", - "S1514-", - "G1515-", - "Y1516-", - "G1517-", - "K1518-", - "E1519-", - "D1520-", - "A1521-", - "D1522-", - "K1523-", - "P1524-", - "R1525-", - "A1526-", - "C1527-", - "F1528-", - "H1529-", - "H1530-", - "W1531-", - "N1532-", - "Y1533-", - "Y1534-", - "T1535-", - "L1536-", - "S1537-", - "L1538-", - "D1539-", - "Y1540-", - "Y1541-", - "C1542-", - "S1543-", - "Y1544-", - "E1545-", - "D1546-", - "I1547-", - "W1548-", - "R1549-", - "S1550-", - "T1551-", - "W1552-", - "P1553-", - "D1554-", - "Y1555-", - "D1556-", - "P1557-", - "C1558-", - "K1559-", - "S1560-", - "Y1561-", - "I1562-", - "H1563-", - "I1564-", - "E1565-", - "Y1566-", - "R1567-", - "D1568-", - "T1569-", - "W1570-", - "I1571-", - "E1572-", - "S1573-", - "N1574-", - "V1575-", - "L1576-", - "Q1577-", - "Q1578-", - "P1579-", - "P1580-", - "Y1581-", - "T1582-", - "F1583-", - "E1584-", - "F1585-", - "I1586-", - "H1587-", - "D1588-", - "N1589-", - "S1590-", - "N1591-", - "E1592-", - "Y1593-", - "V1594-", - "D1595-", - "K1596-", - "E1597-", - "I1598-", - "S1599-", - "N1600-", - "K1601-", - "L1602-", - "N1603-", - "D1604-", - "L1605-", - "Y1606-", - "N1607-", - "E1608-", - "Y1609-", - "K1610-", - "K1611-", - "I1612-", - "M1613-", - "E1614-", - "Y1615-", - "S1616-", - "D1617-", - "G1618-", - "S1619-", - "L1620-", - "P1621-", - "A1622-", - "S1623-", - "I1624-", - "N1625-", - "R1626-", - "L1627-", - "A1628-", - "K1629-", - "A1630-", - "L1631-", - "T1632-", - "S1633-", - "E1634-", - "G1635-", - "R1636-", - "E1637-", - "I1638-", - "A1639-", - "S1640-", - "V1641-", - "N1642-", - "I1643-", - "D1644-", - "G1645-", - "N1646-", - "L1647-", - "L1648-", - "D1649-", - "I1650-", - "A1651-", - "Y1652-", - "Q1653-", - "A1654-", - "D1655-", - "K1656-", - "E1657-", - "K1658-", - "M1659-", - "A1660-", - "D1661-", - "I1662-", - "Q1663-", - "T1664-", - "R1665-", - "I1666-", - "N1667-", - "D1668-", - "I1669-", - "I1670-", - "R1671-", - "D1672-", - "L1673-", - "F1674-", - "I1675-", - "H1676-", - "T1677-", - "L1678-", - "S1679-", - "D1680-", - "K1681-", - "D1682-", - "I1683-", - "K1684-", - "D1685-", - "I1686-", - "I1687-", - "E1688-", - "S1689-", - "E1690-", - "E1691-", - "G1692-", - "K1693-", - "R1694-", - "C1695-", - "C1696-", - "I1697-", - "I1698-", - "D1699-", - "V1700-", - "K1701-", - "N1702-", - "N1703-", - "L1704-", - "V1705-", - "K1706-", - "K1707-", - "Y1708-", - "Y1709-", - "S1710-", - "I1711-", - "D1712-", - "N1713-", - "Y1714-", - "L1715-", - "C1716-", - "D1717-", - "T1718-", - "L1719-", - "D1720-", - "D1721-", - "Y1722-", - "I1723-", - "Y1724-", - "T1725-", - "S1726-", - "V1727-", - "E1728-", - "Y1729-", - "N1730-", - "K1731-", - "S1732-", - "Y1733-", - "V1734-", - "L1735-", - "V1736-", - "N1737-", - "D1738-", - "T1739-", - "Y1740-", - "M1741-", - "S1742-", - "Y1743-", - "D1744-", - "Y1745-", - "L1746-", - "E1747-", - "S1748-", - "S1749-", - "G1750-", - "V1751-", - "V1752-", - "V1753-", - "L1754-", - "S1755-", - "C1756-", - "Y1757-", - "E1758-", - "M1759-", - "T1760-", - "I1761-", - "I1762-", - "S1763-", - "L1764-", - "D1765-", - "T1766-", - "K1767-", - "D1768-", - "A1769-", - "K1770-", - "D1771-", - "A1772-", - "I1773-", - "E1774-", - "D1775-", - "V1776-", - "I1777-", - "V1778-", - "A1779-", - "S1780-", - "A1781-", - "V1782-", - "A1783-", - "E1784-", - "A1785-", - "L1786-", - "N1787-", - "D1788-", - "M1789-", - "F1790-", - "K1791-", - "E1792-", - "F1793-", - "D1794-", - "K1795-", - "N1796-", - "V1797-", - "S1798-", - "A1799-", - "I1800-", - "I1801-", - "I1802-", - "K1803-", - "E1804-", - "E1805-", - "D1806-", - "N1807-", - "Y1808-", - "L1809-", - "N1810-", - "S1811-", - "S1812-", - "P1813-", - "D1814-", - "I1815-", - "Y1816-", - "H1817-", - "I1818-", - "I1819-", - "Y1820-", - "I1821-", - "I1822-", - "G1823-", - "G1824-", - "T1825-", - "I1826-", - "L1827-", - "L1828-", - "L1829-", - "L1830-", - "V1831-", - "I1832-", - "I1833-", - "L1834-", - "I1835-", - "L1836-", - "A1837-", - "I1838-", - "Y1839-", - "I1840-", - "A1841-", - "R1842-", - "N1843-", - "K1844-", - "Y1845-", - "R1846-", - "T1847-", - "R1848-", - "K1849-", - "Y1850-", - "E1851-", - "I1852-", - "M1853-", - "K1854-", - "Y1855-", - "D1856-", - "N1857-", - "M1858-", - "S1859-", - "I1860-", - "K1861-", - "S1862-", - "E1863-", - "H1864-", - "H1865-", - "D1866-", - "S1867-", - "L1868-", - "E1869-", - "T1870-", - "V1871-", - "S1872-", - "M1873-", - "E1874-", - "I1875-", - "I1876-", - "D1877-", - "N1878-", - "R1879-", - "Y1880-", - "*1881-" - ] - }, - "labels": { - "aa": "OPG015: M1-, E2-, S3-, V4-, D5-, F6-, M7-, A8-, V9-, D10-, E11-, Q12-, F13-, H14-, D15-, D16-, L17-, D18-, L19-, W20-, S21-, L22-, S23-, L24-, V25-, D26-, D27-, Y28-, K29-, K30-, H31-, G32-, L33-, G34-, V35-, D36-, C37-, Y38-, V39-, L40-, E41-, P42-, V43-, V44-, D45-, R46-, K47-, I48-, F49-, D50-, R51-, F52-, L53-, L54-, E55-, P56-, I57-, C58-, D59-, P60-, V61-, D62-, V63-, L64-, Y65-, D66-, Y67-, F68-, R69-, I70-, H71-, R72-, D73-, N74-, I75-, D76-, Q77-, Y78-, I79-, V80-, D81-, R82-, L83-, F84-, A85-, Y86-, I87-, T88-, Y89-, K90-, D91-, I92-, I93-, S94-, A95-, L96-, V97-, S98-, K99-, N100-, Y101-, M102-, E103-, D104-, I105-, F106-, S107-, I108-, I109-, I110-, K111-, N112-, C113-, N114-, S115-, V116-, Q117-, D118-, L119-, L120-, L121-, Y122-, Y123-, L124-, S125-, N126-, A127-, Y128-, V129-, E130-, I131-, D132-, I133-, V134-, D135-, L136-, M137-, V138-, D139-, H140-, G141-, A142-, V143-, I144-, Y145-, K146-, I147-, E148-, C149-, L150-, N151-, A152-, Y153-, F154-, R155-, G156-, I157-, C158-, K159-, K160-, E161-, S162-, S163-, V164-, V165-, E166-, F167-, I168-, L169-, N170-, C171-, G172-, I173-, P174-, D175-, E176-, N177-, D178-, V179-, K180-, L181-, D182-, L183-, Y184-, K185-, I186-, I187-, Q188-, Y189-, T190-, R191-, G192-, F193-, L194-, V195-, D196-, E197-, P198-, T199-, V200-, L201-, E202-, I203-, Y204-, K205-, L206-, C207-, I208-, P209-, Y210-, I211-, E212-, D213-, I214-, N215-, Q216-, L217-, D218-, A219-, G220-, G221-, R222-, T223-, L224-, L225-, Y226-, R227-, A228-, I229-, Y230-, A231-, G232-, Y233-, I234-, D235-, L236-, V237-, S238-, W239-, L240-, L241-, E242-, N243-, G244-, A245-, N246-, V247-, N248-, A249-, V250-, M251-, S252-, N253-, G254-, Y255-, T256-, C257-, L258-, D259-, V260-, A261-, V262-, D263-, R264-, G265-, S266-, V267-, I268-, A269-, R270-, R271-, E272-, A273-, H274-, L275-, K276-, I277-, L278-, E279-, I280-, L281-, L282-, R283-, E284-, P285-, L286-, S287-, I288-, D289-, C290-, I291-, K292-, L293-, A294-, I295-, L296-, N297-, N298-, T299-, I300-, E301-, N302-, H303-, D304-, V305-, I306-, K307-, L308-, C309-, I310-, K311-, Y312-, F313-, M314-, M315-, V316-, D317-, Y318-, S319-, L320-, C321-, N322-, V323-, Y324-, A325-, S326-, S327-, L328-, F329-, D330-, Y331-, I332-, I333-, D334-, C335-, K336-, Q337-, E338-, L339-, E340-, Y341-, I342-, R343-, Q344-, M345-, K346-, I347-, H348-, N349-, T350-, T351-, M352-, Y353-, E354-, L355-, I356-, Y357-, N358-, R359-, D360-, K361-, N362-, K363-, H364-, A365-, S366-, H367-, I368-, L369-, H370-, R371-, Y372-, S373-, K374-, H375-, P376-, V377-, L378-, T379-, Q380-, C381-, I382-, T383-, K384-, G385-, F386-, K387-, I388-, Y389-, T390-, E391-, V392-, T393-, E394-, Q395-, V396-, T397-, K398-, A399-, L400-, N401-, R402-, R403-, A404-, L405-, I406-, D407-, E408-, I409-, I410-, N411-, N412-, V413-, S414-, T415-, D416-, D417-, N418-, L419-, L420-, S421-, K422-, L423-, P424-, L425-, E426-, I427-, R428-, D429-, L430-, I431-, V432-, S433-, Q434-, A435-, V436-, I437-, *438-; OPG019: M1-, S2-, I3-, K4-, Y5-, L6-, M7-, L8-, L9-, F10-, A11-, A12-, M13-, I14-, I15-, R16-, S17-, L18-, A19-, D20-, S21-, G22-, N23-, A24-, I25-, E26-, T27-, T28-, S29-, P30-, E31-, I32-, T33-, N34-, A35-, T36-, T37-, D38-, I39-, P40-, A41-, I42-, R43-, L44-, C45-, G46-, P47-, E48-, G49-, D50-, G51-, Y52-, C53-, L54-, H55-, G56-, D57-, C58-, I59-, H60-, A61-, R62-, D63-, I64-, D65-, G66-, M67-, Y68-, C69-, R70-, C71-, S72-, H73-, G74-, Y75-, T76-, G77-, I78-, R79-, C80-, Q81-, H82-, V83-, V84-, L85-, V86-, D87-, Y88-, Q89-, R90-, S91-, G92-, K93-, P94-, D95-, T96-, T97-, T98-, S99-, Y100-, I101-, P102-, S103-, L104-, G105-, I106-, V107-, L108-, V109-, L110-, V111-, G112-, I113-, I114-, I115-, T116-, C117-, C118-, L119-, L120-, S121-, V122-, Y123-, M124-, F125-, T126-, R127-, R128-, T129-, K130-, L131-, P132-, I133-, Q134-, D135-, M136-, V137-, V138-, L139-, Y140-, F141-, L142-, *143-; OPG021: M1-, E2-, F3-, D4-, P5-, V6-, K7-, I8-, N9-, T10-, S11-, S12-, I13-, D14-, H15-, V16-, T17-, I18-, L19-, Q20-, Y21-, I22-, D23-, E24-, P25-, N26-, D27-, I28-, R29-, L30-, T31-, V32-, C33-, I34-, I35-, R36-, N37-, V38-, N39-, N40-, I41-, T42-, Y43-, Y44-, I45-, N46-, I47-, T48-, K49-, I50-, N51-, P52-, H53-, L54-, A55-, N56-, R57-, F58-, R59-, A60-, W61-, K62-, K63-, R64-, I65-, A66-, G67-, R68-, D69-, Y70-, M71-, T72-, N73-, L74-, S75-, R76-, D77-, T78-, G79-, I80-, Q81-, Q82-, S83-, K84-, L85-, T86-, E87-, T88-, I89-, R90-, N91-, C92-, Q93-, K94-, N95-, K96-, N97-, I98-, Y99-, G100-, L101-, Y102-, I103-, H104-, Y105-, N106-, L107-, V108-, I109-, N110-, V111-, V112-, I113-, D114-, W115-, I116-, T117-, D118-, V119-, I120-, V121-, Q122-, S123-, I124-, L125-, R126-, G127-, L128-, V129-, N130-, W131-, Y132-, I133-, A134-, N135-, N136-, T137-, Y138-, T139-, P140-, N141-, T142-, P143-, N144-, N145-, T146-, T147-, T148-, I149-, S150-, E151-, L152-, D153-, I154-, I155-, K156-, I157-, L158-, D159-, K160-, Y161-, E162-, D163-, M164-, Y165-, R166-, V167-, S168-, K169-, E170-, K171-, E172-, C173-, G174-, I175-, C176-, Y177-, E178-, V179-, V180-, Y181-, S182-, K183-, R184-, L185-, E186-, N187-, D188-, R189-, Y190-, F191-, G192-, L193-, L194-, D195-, S196-, C197-, N198-, H199-, I200-, F201-, C202-, I203-, T204-, C205-, I206-, N207-, I208-, W209-, H210-, R211-, T212-, R213-, R214-, E215-, T216-, G217-, A218-, S219-, D220-, N221-, C222-, P223-, I224-, C225-, R226-, T227-, R228-, F229-, K230-, K231-, I232-, T233-, M234-, S235-, K236-, F237-, Y238-, K239-, L240-, V241-, N242-, *243-; OPG022: M1-, R2-, I3-, L4-, F5-, L6-, I7-, A8-, F9-, M10-, Y11-, G12-, C13-, V14-, H15-, S16-, Y17-, V18-, N19-, A20-, V21-, E22-, T23-, K24-, C25-, P26-, N27-, L28-, A29-, I30-, V31-, T32-, S33-, S34-, G35-, E36-, F37-, H38-, C39-, S40-, G41-, C42-, V43-, E44-, R45-, M46-, P47-, G48-, F49-, S50-, Y51-, M52-, Y53-, W54-, L55-, A56-, N57-, D58-, M59-, K60-, S61-, D62-, E63-, D64-, T65-, K66-, F67-, I68-, E69-, H70-, L71-, G72-, G73-, G74-, I75-, K76-, E77-, D78-, E79-, T80-, V81-, R82-, T83-, T84-, D85-, G86-, G87-, I88-, T89-, T90-, L91-, R92-, K93-, V94-, L95-, H96-, V97-, T98-, D99-, T100-, N101-, K102-, F103-, A104-, H105-, Y106-, R107-, F108-, T109-, C110-, V111-, L112-, I113-, T114-, L115-, D116-, G117-, V118-, S119-, K120-, K121-, N122-, I123-, W124-, L125-, K126-, *127-; OPG023: D392N, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-, N526-, A527-, Y528-, A529-, I530-, K531-, Q532-, C533-, I534-, K535-, Y536-, T537-, M538-, I539-, I540-, D541-, D542-, C543-, T544-, S545-, S546-, K547-, I548-, P549-, E550-, S551-, I552-, S553-, Q554-, R555-, Y556-, N557-, D558-, Y559-, I560-, D561-, L562-, C563-, N564-, Q565-, E566-, L567-, N568-, E569-, M570-, K571-, K572-, I573-, M574-, V575-, G576-, G577-, N578-, T579-, M580-, F581-, S582-, L583-, I584-, F585-, T586-, E587-, H588-, G589-, A590-, K591-, I592-, I593-, H594-, R595-, Y596-, A597-, N598-, N599-, P600-, E601-, L602-, R603-, A604-, Y605-, Y606-, E607-, S608-, K609-, Q610-, N611-, K612-, I613-, Y614-, V615-, E616-, A617-, Y618-, D619-, I620-, I621-, S622-, D623-, A624-, I625-, V626-, K627-, H628-, N629-, K630-, I631-, H632-, K633-, T634-, I635-, I636-, K637-, S638-, V639-, D640-, D641-, N642-, T643-, Y644-, I645-, S646-, N647-, L648-, P649-, Y650-, T651-, I652-, K653-, Y654-, K655-, I656-, F657-, E658-, Q659-, Q660-, *661-; OPG057: E353K; OPG210: N1301X, R1302-, M1303-, F1304-, A1305-, T1306-, L1307-, A1308-, R1309-, G1310-, M1311-, P1312-, F1313-, R1314-, S1315-, T1316-, Y1317-, C1318-, D1319-, N1320-, R1321-, R1322-, R1323-, S1324-, G1325-, C1326-, Y1327-, Y1328-, A1329-, G1330-, I1331-, P1332-, F1333-, H1334-, E1335-, D1336-, S1337-, V1338-, E1339-, T1340-, D1341-, I1342-, H1343-, Y1344-, G1345-, P1346-, E1347-, I1348-, M1349-, L1350-, K1351-, E1352-, T1353-, Y1354-, D1355-, I1356-, N1357-, S1358-, I1359-, D1360-, P1361-, R1362-, V1363-, I1364-, T1365-, K1366-, S1367-, K1368-, T1369-, H1370-, F1371-, P1372-, A1373-, P1374-, L1375-, S1376-, V1377-, K1378-, F1379-, M1380-, V1381-, D1382-, N1383-, L1384-, G1385-, N1386-, G1387-, Y1388-, D1389-, N1390-, P1391-, N1392-, S1393-, F1394-, W1395-, E1396-, D1397-, A1398-, K1399-, T1400-, K1401-, K1402-, R1403-, T1404-, Y1405-, S1406-, A1407-, M1408-, T1409-, I1410-, K1411-, V1412-, L1413-, P1414-, C1415-, T1416-, V1417-, R1418-, N1419-, K1420-, N1421-, I1422-, D1423-, F1424-, G1425-, Y1426-, N1427-, Y1428-, G1429-, D1430-, I1431-, I1432-, S1433-, N1434-, M1435-, V1436-, Y1437-, L1438-, Q1439-, S1440-, T1441-, S1442-, Q1443-, D1444-, Y1445-, G1446-, D1447-, G1448-, T1449-, K1450-, Y1451-, T1452-, F1453-, K1454-, S1455-, V1456-, T1457-, R1458-, S1459-, D1460-, H1461-, E1462-, C1463-, E1464-, S1465-, S1466-, L1467-, D1468-, L1469-, T1470-, S1471-, K1472-, E1473-, V1474-, T1475-, V1476-, T1477-, C1478-, P1479-, A1480-, F1481-, S1482-, I1483-, P1484-, R1485-, N1486-, I1487-, S1488-, T1489-, Y1490-, E1491-, G1492-, L1493-, C1494-, F1495-, S1496-, V1497-, T1498-, T1499-, S1500-, K1501-, D1502-, H1503-, C1504-, A1505-, T1506-, G1507-, I1508-, G1509-, W1510-, L1511-, K1512-, S1513-, S1514-, G1515-, Y1516-, G1517-, K1518-, E1519-, D1520-, A1521-, D1522-, K1523-, P1524-, R1525-, A1526-, C1527-, F1528-, H1529-, H1530-, W1531-, N1532-, Y1533-, Y1534-, T1535-, L1536-, S1537-, L1538-, D1539-, Y1540-, Y1541-, C1542-, S1543-, Y1544-, E1545-, D1546-, I1547-, W1548-, R1549-, S1550-, T1551-, W1552-, P1553-, D1554-, Y1555-, D1556-, P1557-, C1558-, K1559-, S1560-, Y1561-, I1562-, H1563-, I1564-, E1565-, Y1566-, R1567-, D1568-, T1569-, W1570-, I1571-, E1572-, S1573-, N1574-, V1575-, L1576-, Q1577-, Q1578-, P1579-, P1580-, Y1581-, T1582-, F1583-, E1584-, F1585-, I1586-, H1587-, D1588-, N1589-, S1590-, N1591-, E1592-, Y1593-, V1594-, D1595-, K1596-, E1597-, I1598-, S1599-, N1600-, K1601-, L1602-, N1603-, D1604-, L1605-, Y1606-, N1607-, E1608-, Y1609-, K1610-, K1611-, I1612-, M1613-, E1614-, Y1615-, S1616-, D1617-, G1618-, S1619-, L1620-, P1621-, A1622-, S1623-, I1624-, N1625-, R1626-, L1627-, A1628-, K1629-, A1630-, L1631-, T1632-, S1633-, E1634-, G1635-, R1636-, E1637-, I1638-, A1639-, S1640-, V1641-, N1642-, I1643-, D1644-, G1645-, N1646-, L1647-, L1648-, D1649-, I1650-, A1651-, Y1652-, Q1653-, A1654-, D1655-, K1656-, E1657-, K1658-, M1659-, A1660-, D1661-, I1662-, Q1663-, T1664-, R1665-, I1666-, N1667-, D1668-, I1669-, I1670-, R1671-, D1672-, L1673-, F1674-, I1675-, H1676-, T1677-, L1678-, S1679-, D1680-, K1681-, D1682-, I1683-, K1684-, D1685-, I1686-, I1687-, E1688-, S1689-, E1690-, E1691-, G1692-, K1693-, R1694-, C1695-, C1696-, I1697-, I1698-, D1699-, V1700-, K1701-, N1702-, N1703-, L1704-, V1705-, K1706-, K1707-, Y1708-, Y1709-, S1710-, I1711-, D1712-, N1713-, Y1714-, L1715-, C1716-, D1717-, T1718-, L1719-, D1720-, D1721-, Y1722-, I1723-, Y1724-, T1725-, S1726-, V1727-, E1728-, Y1729-, N1730-, K1731-, S1732-, Y1733-, V1734-, L1735-, V1736-, N1737-, D1738-, T1739-, Y1740-, M1741-, S1742-, Y1743-, D1744-, Y1745-, L1746-, E1747-, S1748-, S1749-, G1750-, V1751-, V1752-, V1753-, L1754-, S1755-, C1756-, Y1757-, E1758-, M1759-, T1760-, I1761-, I1762-, S1763-, L1764-, D1765-, T1766-, K1767-, D1768-, A1769-, K1770-, D1771-, A1772-, I1773-, E1774-, D1775-, V1776-, I1777-, V1778-, A1779-, S1780-, A1781-, V1782-, A1783-, E1784-, A1785-, L1786-, N1787-, D1788-, M1789-, F1790-, K1791-, E1792-, F1793-, D1794-, K1795-, N1796-, V1797-, S1798-, A1799-, I1800-, I1801-, I1802-, K1803-, E1804-, E1805-, D1806-, N1807-, Y1808-, L1809-, N1810-, S1811-, S1812-, P1813-, D1814-, I1815-, Y1816-, H1817-, I1818-, I1819-, Y1820-, I1821-, I1822-, G1823-, G1824-, T1825-, I1826-, L1827-, L1828-, L1829-, L1830-, V1831-, I1832-, I1833-, L1834-, I1835-, L1836-, A1837-, I1838-, Y1839-, I1840-, A1841-, R1842-, N1843-, K1844-, Y1845-, R1846-, T1847-, R1848-, K1849-, Y1850-, E1851-, I1852-, M1853-, K1854-, Y1855-, D1856-, N1857-, M1858-, S1859-, I1860-, K1861-, S1862-, E1863-, H1864-, H1865-, D1866-, S1867-, L1868-, E1869-, T1870-, V1871-, S1872-, M1873-, E1874-, I1875-, I1876-, D1877-, N1878-, R1879-, Y1880-, *1881-" - } - } - }, - { - "name": "MPXV/003/19", - "node_attrs": { - "div": 518, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "date": { - "value": "2019-01-16" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "strain_original": { - "value": "MPXV/003/19" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP612674" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C11555T", - "G28645A", - "G75967A", - "T76079-", - "G94840A", - "C188503T", - "A196603-", - "A196604-", - "A196605-", - "A196606-" - ], - "OPG023": [ - "R449Q" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG115": [ - "E61K" - ] - }, - "labels": { - "aa": "OPG023: R449Q; OPG097: K266X, *345X; OPG115: E61K" - } - } - }, - { - "name": "MPXV/039/19", - "node_attrs": { - "div": 520, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "date": { - "value": "2019-04-29" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "strain_original": { - "value": "MPXV/039/19" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP612681" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A1231G", - "G22971A", - "G23711A", - "G33177A", - "T76079-", - "G77635A", - "C83496T", - "C90945T", - "T121116-", - "G138571A", - "T146862-", - "A146863-", - "T146864-", - "T146865-", - "T146866-", - "T146867-", - "A146868-", - "T146869-", - "A146870-", - "T146871-", - "T146872-", - "T146873-", - "T146874-", - "A146875-", - "T146876-", - "A146877-", - "T146878-", - "T146879-", - "T146880-", - "A173300-", - "T173301-", - "T187080-" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG098": [ - "D246N" - ], - "OPG138": [ - "N6X", - "*191X" - ], - "OPG156": [ - "T280I" - ] - }, - "labels": { - "aa": "OPG097: K266X, *345X; OPG098: D246N; OPG138: N6X, *191X; OPG156: T280I" - } - } - }, - { - "name": "MPXV/104/19", - "node_attrs": { - "div": 522, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "date": { - "value": "2019-11-16" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "strain_original": { - "value": "MPXV/104/19" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP612688" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "G1126A", - "G2039A", - "G2152A", - "C6948T", - "C47224T", - "T76079-", - "C77726T", - "C143845T", - "G152431A", - "C166786T", - "A173300-", - "T173301-", - "G184037T", - "C184535T", - "C195058T", - "C195171T", - "C196084T" - ], - "OPG002": [ - "S238L" - ], - "OPG066": [ - "E69K" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG099": [ - "S21F" - ], - "OPG192": [ - "S19L" - ] - }, - "labels": { - "aa": "OPG002: S238L; OPG066: E69K; OPG097: K266X, *345X; OPG099: S21F; OPG192: S19L" - } - } - }, - { - "name": "NODE_0000088", - "node_attrs": { - "div": 514, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T146862-", - "A146863-", - "T146864-", - "T146865-", - "T146866-", - "T146867-", - "A146868-", - "T146869-", - "A146870-", - "T146871-", - "T146872-", - "T146873-", - "T146874-", - "A146875-", - "T146876-", - "A146877-", - "T146878-", - "T146879-", - "T146880-", - "G151929A", - "A173300-", - "T173301-", - "-196601A", - "-196602A" - ], - "OPG178": [ - "E141K" - ] - }, - "labels": { - "aa": "OPG178: E141K" - } - }, - "children": [ - { - "name": "MPXV/042/19", - "node_attrs": { - "div": 516, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "date": { - "value": "2019-04-29" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "strain_original": { - "value": "MPXV/042/19" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP612683" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "T76079-", - "G81523A", - "C141757T" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG105": [ - "S133N" - ] - }, - "labels": { - "aa": "OPG097: K266X, *345X; OPG105: S133N" - } - } - }, - { - "name": "NODE_0000089", - "node_attrs": { - "div": 515, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C39767T" - ] - } - }, - "children": [ - { - "name": "MPXV-Singapore", - "node_attrs": { - "div": 517, - "author": { - "author": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y.", - "value": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "date": { - "value": "2019-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "strain_original": { - "value": "MPXV-Singapore" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "MT903342" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Singapore" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "C43927T", - "-146862T", - "-146863A", - "-146864T", - "-146865T", - "-146866T", - "-146867T", - "-146868A", - "-146869T", - "-146870A", - "-146871T", - "-146872T", - "-146873T", - "-146874T", - "-146875A", - "-146876T", - "-146877A", - "-146878T", - "-146879T", - "-146880T", - "C170573T", - "-173274A", - "-173275T", - "-173276A", - "-173277T", - "-173278A", - "-173279T", - "-173280A", - "-173281T", - "-173282A", - "-173283T", - "-173284A", - "-173285T", - "-173286A", - "-173287T", - "-173288A", - "-173289T", - "-173290A", - "-173291T", - "-173292A", - "-173293T", - "-173294A", - "-173295T", - "-173296A", - "-173297T", - "-173298A", - "-173299T", - "-173300A", - "-173301T", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-", - "A196601-" - ], - "OPG064": [ - "E658K" - ], - "OPG198": [ - "S179L" - ] - }, - "labels": { - "aa": "OPG064: E658K; OPG198: S179L" - } - } - }, - { - "name": "MPXV/052/19", - "node_attrs": { - "div": 515, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "date": { - "value": "2019-06-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "strain_original": { - "value": "MPXV/052/19" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP612685" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T595-", - "T596-" - ] - } - } - } - ] - }, - { - "name": "NODE_0000090", - "node_attrs": { - "div": 521, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C13065T", - "C29887T", - "G61329A", - "C72206T", - "G103431A", - "-146862T", - "-146863A", - "-146864T", - "-146865T", - "-146866T", - "-146867T", - "-146868A", - "-146869T", - "-146870A", - "-146871T", - "-146872T", - "-146873T", - "-146874T", - "-146875A", - "-146876T", - "-146877A", - "-146878T", - "-146879T", - "-146880T", - "C165369T", - "-173296A", - "-173297T", - "-173298A", - "-173299T", - "-173300A", - "-173301T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-", - "G188949A", - "T192184C" - ], - "OPG024": [ - "G55E" - ], - "OPG092": [ - "E248K" - ], - "OPG123": [ - "S547L" - ], - "OPG190": [ - "S83F" - ] - }, - "labels": { - "aa": "OPG024: G55E; OPG092: E248K; OPG123: S547L; OPG190: S83F" - } - }, - "children": [ - { - "name": "2091", - "node_attrs": { - "div": 521, - "author": { - "author": "Atkinson,B., Pottage,T., Ngabo,D., Crook,A., Pitman,J., Summers,S., Pullan,S., Lewandowski,K., Furneaux,J., Davies,K., Brooks,T.", - "value": "Atkinson,B., Pottage,T., Ngabo,D., Crook,A., Pitman,J., Summers,S., Pullan,S., Lewandowski,K., Furneaux,J., Davies,K., Brooks,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research" - }, - "date": { - "value": "2019-12-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "strain_original": { - "value": "2091" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OL504741" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T192413C" - ] - } - } - }, - { - "name": "2095", - "node_attrs": { - "div": 521, - "author": { - "author": "Atkinson,B., Pottage,T., Ngabo,D., Crook,A., Pitman,J., Summers,S., Pullan,S., Lewandowski,K., Furneaux,J., Davies,K., Brooks,T.", - "value": "Atkinson,B., Pottage,T., Ngabo,D., Crook,A., Pitman,J., Summers,S., Pullan,S., Lewandowski,K., Furneaux,J., Davies,K., Brooks,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research" - }, - "date": { - "value": "2019-12-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "strain_original": { - "value": "2095" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OL504742" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000091", - "node_attrs": { - "div": 515, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G25661A", - "C39119T", - "-173274A", - "-173275T", - "-173276A", - "-173277T", - "-173278A", - "-173279T", - "-173280A", - "-173281T", - "-173282A", - "-173283T", - "-173284A", - "-173285T", - "-173286A", - "-173287T", - "-173288A", - "-173289T", - "-173290A", - "-173291T", - "-173292A", - "-173293T", - "-173294A", - "-173295T", - "-173296A", - "-173297T", - "-173298A", - "-173299T" - ] - } - }, - "children": [ - { - "name": "MPXV/018/19", - "node_attrs": { - "div": 523, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "date": { - "value": "2019-03-18" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "strain_original": { - "value": "MPXV/018/19" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP612679" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C8500T", - "G79538A", - "G81354A", - "G84416A", - "C88736T", - "G100642A", - "C138791T", - "C161616T" - ], - "OPG102": [ - "D152N" - ], - "OPG105": [ - "E77K" - ], - "OPG109": [ - "E238K" - ], - "OPG119": [ - "R86K" - ], - "OPG156": [ - "D207N" - ] - }, - "labels": { - "aa": "OPG102: D152N; OPG105: E77K; OPG109: E238K; OPG119: R86K; OPG156: D207N" - } - } - }, - { - "name": "NODE_0000092", - "node_attrs": { - "div": 516, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T595-", - "G162243A", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A196603-" - ] - } - }, - "children": [ - { - "name": "MPXV-UK_P2", - "node_attrs": { - "div": 516, - "author": { - "author": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y.", - "value": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "date": { - "value": "2018-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "strain_original": { - "value": "MPXV-UK_P2" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "MT903344" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-", - "-196603A" - ] - } - } - }, - { - "name": "MPXV-UK_P3", - "node_attrs": { - "div": 516, - "author": { - "author": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y.", - "value": "Mauldin,M.R., McCollum,A.M., Nakazawa,Y.J., Mandra,A., Whitehouse,E.R., Davidson,W., Zhao,H., Gao,J., Li,Y., Doty,J., Yinka-Ogunleye,A., Akinpelu,A., Aruna,O., Naidoo,D., Lewandowski,K., Afrough,B., Graham,V., Aarons,E., Hewson,R., Vipond,R., Dunning,J., Chand,M., Brown,C., Cohen-Gihon,I., Erez,N., Shifman,O., Israeli,O., Sharon,M., Schwartz,E., Beth-Din,A., Zvi,A., Mak,T.M., Ng,Y.K., Cui,L., Lin,R.T.P., Olson,V.A., Brooks,T., Paran,N., Ihekweazu,C., Reynolds,M.G., Nakazawa,Y." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "date": { - "value": "2018-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "strain_original": { - "value": "MPXV-UK_P3" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "MT903345" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-" - ] - } - } - }, - { - "name": "NODE_0000093", - "node_attrs": { - "div": 519, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G1262A", - "C3818T", - "G124130A", - "C128698T", - "T133099-", - "C133164-", - "A133165-", - "A133166-", - "T133167-", - "C133168-", - "T133169-", - "T133170-", - "T133171-", - "C133172-", - "T133173-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "A173300-", - "T173301-", - "-179163C", - "-179172C", - "G193392A", - "C195948T" - ], - "OPG001": [ - "S105L" - ], - "OPG003": [ - "D264N" - ], - "OPG145": [ - "E62K" - ], - "OPG150": [ - "S307L" - ] - }, - "labels": { - "aa": "OPG001: S105L; OPG003: D264N; OPG145: E62K; OPG150: S307L" - } - }, - "children": [ - { - "name": "MPXV/058/19", - "node_attrs": { - "div": 524, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "date": { - "value": "2019-08-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "strain_original": { - "value": "MPXV/058/19" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP612687" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "T597-", - "C756T", - "G2039A", - "G168365A", - "A173302-", - "T173303-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "C188605A", - "A188606C", - "G188607A", - "T193455A", - "C195171T", - "G196454-", - "A196604-" - ], - "OPG002": [ - "S238L" - ], - "OPG003": [ - "L285I" - ], - "OPG195": [ - "E46K" - ] - }, - "labels": { - "aa": "OPG002: S238L; OPG003: L285I; OPG195: E46K" - } - } - }, - { - "name": "NODE_0000094", - "node_attrs": { - "div": 520, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G81275A" - ] - } - }, - "children": [ - { - "name": "MPXV/053/19", - "node_attrs": { - "div": 521, - "author": { - "author": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O.", - "value": "Ndodo,N., Ashcroft,J., Lewandowski,K., Yinka-Ogunleye,A., Chukwu,C., Ahmad,A., King,D., Akinpelu,A., Maluquer de Motes,C., Ribeca,P., Summer,R.P., Rambaut,A., Chester,M., Maishman,T., Babatunde,O., Mba,N., Aruna,O., Pullan,S.T., Gannon,B., Brown,C., Ihekweazu,C., Adetifa,I., Ulaeto,D.O." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences" - }, - "date": { - "value": "2019-07-01" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1" - }, - "strain_original": { - "value": "MPXV/053/19" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP612686" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Nigeria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "T76079-", - "G88640A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-196601A", - "-196602A", - "-196603A" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG109": [ - "R270C" - ] - }, - "labels": { - "aa": "OPG097: K266X, *345X; OPG109: R270C" - } - } - }, - { - "name": "NODE_0000095", - "node_attrs": { - "div": 545, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G2591A", - "G3522A", - "C7771T", - "G14000T", - "G15428A", - "G21723A", - "G30367A", - "G31053A", - "G34459A", - "G37202A", - "G38360A", - "C38662T", - "G52885A", - "G54117A", - "G54635A", - "G64297A", - "C73066T", - "C82373T", - "G82451A", - "G95034A", - "G124674A", - "-133099T", - "C162331T", - "-173274A", - "-173275T", - "-173276A", - "-173277T", - "-173278A", - "-173279T", - "-173280A", - "-173281T", - "-173282A", - "-173283T", - "-173284A", - "-173285T", - "-173286A", - "-173287T", - "-173288A", - "-173289T", - "-173290A", - "-173291T", - "-173292A", - "-173293T", - "-173294A", - "-173295T", - "-173296A", - "-173297T", - "-173298A", - "-173299T", - "-173300A", - "-173301T", - "G178133A", - "G181980A", - "G186578A", - "C193688T", - "C194619T" - ], - "OPG002": [ - "S54F" - ], - "OPG025": [ - "A423D" - ], - "OPG047": [ - "R48C" - ], - "OPG053": [ - "P78S" - ], - "OPG056": [ - "E125K" - ], - "OPG071": [ - "L108F" - ], - "OPG072": [ - "D56N" - ], - "OPG093": [ - "S30L" - ], - "OPG145": [ - "R243Q" - ], - "OPG210": [ - "D209N", - "M1741I" - ] - }, - "labels": { - "aa": "OPG002: S54F; OPG025: A423D; OPG047: R48C; OPG053: P78S; OPG056: E125K; OPG071: L108F; OPG072: D56N; OPG093: S30L; OPG145: R243Q; OPG210: D209N, M1741I", - "clade": "A.1.1" - } - }, - "children": [ - { - "name": "MPXV_USA_2021_MD", - "node_attrs": { - "div": 548, - "author": { - "author": "Gigante,C.M., Myers,R., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Blythe,D., Li,Y.", - "value": "Gigante,C.M., Myers,R., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Blythe,D., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "date": { - "value": "2021-11-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "A.1.1" - }, - "strain_original": { - "value": "MPXV_USA_2021_MD" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON676708" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C79348T", - "C86979T", - "C133714T", - "G169718-", - "A169719-", - "T169720-", - "T169721-", - "C169722-", - "A169723-", - "A169727T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-" - ], - "OPG197": [ - "D17-", - "S18-", - "T20S" - ] - }, - "labels": { - "aa": "OPG197: D17-, S18-, T20S" - } - } - }, - { - "name": "NODE_0000096", - "node_attrs": { - "div": 556, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G3111A", - "C39139T", - "G73239A", - "G74205A", - "G77383A", - "C84587T", - "C150469T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "A151461C", - "G155795A", - "G170262A", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-", - "C183519T", - "C194099T" - ], - "OPG057": [ - "E353K" - ], - "OPG093": [ - "D88N" - ], - "OPG094": [ - "M142I" - ], - "OPG098": [ - "E162K" - ], - "OPG176": [ - "H221Y" - ], - "OPG210": [ - "P722S" - ] - }, - "labels": { - "aa": "OPG057: E353K; OPG093: D88N; OPG094: M142I; OPG098: E162K; OPG176: H221Y; OPG210: P722S", - "clade": "B.1" - } - }, - "children": [ - { - "name": "MPXV/human/Japan/Tokyo/TKY220091/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/TKY220091/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "LC722946" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Japan" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C13653T", - "C116100T", - "G150376A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG025": [ - "D539N" - ], - "OPG176": [ - "D190N" - ] - }, - "labels": { - "aa": "OPG025: D539N; OPG176: D190N" - } - } - }, - { - "name": "INMI-Pt1", - "node_attrs": { - "div": 556, - "author": { - "author": "Gruber,C.E.M., Rueca,M., Gramigna,G., Carletti,F., Butera,O., Fabeni,L., Specchiarello,E., Meschi,S., Colavita,F., Minosse,C., Francalancia,M., Lapa,D., Garbuglia,A.R., Giombini,E.", - "value": "Gruber,C.E.M., Rueca,M., Gramigna,G., Carletti,F., Butera,O., Fabeni,L., Specchiarello,E., Meschi,S., Colavita,F., Minosse,C., Francalancia,M., Lapa,D., Garbuglia,A.R., Giombini,E." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Laboratory of Virology, INMI Lazzaro Spallanzani IRCCS, Italy" - }, - "date": { - "value": "2022-05-18" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "INMI-Pt1" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON614676" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Italy" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "MPXV_2022_NL001", - "node_attrs": { - "div": 558, - "author": { - "author": "Oude Munnink,B.B., Boter,M., Wellers,B., Molenkamp,R., Sikkema,R.S., Koopmans,M.", - "value": "Oude Munnink,B.B., Boter,M., Wellers,B., Molenkamp,R., Sikkema,R.S., Koopmans,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Public Health Virology, Erasmus Medical Centre, The Netherlands" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV_2022_NL001" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON615424" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Netherlands" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G155611A", - "G171003A", - "A178777-", - "C178778-", - "A178779-", - "C178780-", - "G178781-", - "A178782-", - "A178783-", - "T178784-", - "A178785-", - "T178786-", - "G178787-", - "T178788-", - "A178789-", - "T178790-", - "G178791-", - "A178792-", - "C178793-", - "G178794-", - "G178795-", - "A178796-", - "T178797-", - "G178798-", - "G178799-", - "G178800-", - "A178801-", - "A178802-", - "T178803-", - "T178804-", - "G178805-", - "G178806-", - "T178807-", - "A178808-", - "A178809-", - "C178810-", - "G178811-", - "A178812-", - "T178813-", - "G178814-", - "A178815-", - "C178816-", - "A178817-", - "G178818-", - "A178819-", - "A178820-", - "A178821-", - "G178822-", - "C178823-", - "A178824-", - "G178825-", - "A178826-", - "T178827-", - "T178828-", - "G178829-", - "T178830-", - "C178831-", - "A178832-", - "G178833-", - "C178834-", - "T178835-", - "C178836-", - "T178837-", - "G178838-", - "C178839-", - "A178840-", - "T178841-", - "A178842-", - "C178843-", - "T178844-", - "A178845-", - "T178846-", - "T178847-", - "C178848-", - "T178849-", - "T178850-", - "C178851-", - "A178852-", - "T178853-", - "G178854-", - "A178855-", - "C178856-", - "A178857-", - "A178858-", - "T178859-", - "A178860-", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "-196603A" - ], - "OPG199": [ - "E6K" - ] - }, - "labels": { - "aa": "OPG199: E6K" - } - } - }, - { - "name": "MPXV_UK_2022_4", - "node_attrs": { - "div": 558, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Pullan,S.T., Carter,D.P., Crook,J.M., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Pullan,S.T., Carter,D.P., Crook,J.M., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Research & Evaluation, UKHSA, UK" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV_UK_2022_4" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON619838" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C147011T", - "G172095A" - ] - } - } - }, - { - "name": "MPX/UZ_REGA_2/Belgium/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Microbiology, Immunology & Transplantation, KU Leuven, Rega Institute, Belgium" - }, - "date": { - "value": "2022-05-22" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPX/UZ_REGA_2/Belgium/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON622713" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C4629T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "G192581A" - ] - } - } - }, - { - "name": "MPXV-CH-38156923/2022", - "node_attrs": { - "div": 556, - "author": { - "author": "Laubscher,F., Schibler,M., Kaiser,L., Renzoni,A.", - "value": "Laubscher,F., Schibler,M., Kaiser,L., Renzoni,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Laboratory of Viorology, University Hospital of Geneva, Switzerland" - }, - "date": { - "value": "2022-05-24" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV-CH-38156923/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON622720" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Switzerland" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ] - } - } - }, - { - "name": "MPxV/VIDRL01/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Hammerschlag,Y., MacLeod,G., Papadakis,G., Adnan Sanchez,A., Druce,J., Savic,I., Taiaroa,G., Roberts,J., Caly,L., Williamson,D.A., Cheng,A.C., McMahon,J.H.", - "value": "Hammerschlag,Y., MacLeod,G., Papadakis,G., Adnan Sanchez,A., Druce,J., Savic,I., Taiaroa,G., Roberts,J., Caly,L., Williamson,D.A., Cheng,A.C., McMahon,J.H." - }, - "region": { - "value": "Oceania" - }, - "institution": { - "value": "Victorian Infectious Diseases Reference Laboratory, Doherty Institute, Australia" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPxV/VIDRL01/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON631963" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Australia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C21128T", - "C133077T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "-196603A" - ], - "OPG037": [ - "E436K" - ] - }, - "labels": { - "aa": "OPG037: E436K" - } - } - }, - { - "name": "2022/2 SLO", - "node_attrs": { - "div": 556, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia" - }, - "date": { - "value": "2022-05-24" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "2022/2 SLO" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON631241" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV_GSTT_Patient1", - "node_attrs": { - "div": 560, - "author": { - "author": "Alcolea-Medina,A., Charalampous,T., Snell,L.B., Batra,R., Edgeworth,J.D.", - "value": "Alcolea-Medina,A., Charalampous,T., Snell,L.B., Batra,R., Edgeworth,J.D." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Clinical Infection & Diagnostics Research, Kings College London, St Thomas Hospital, UK" - }, - "date": { - "value": "2022-05-11" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV_GSTT_Patient1" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON645312" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "T597-", - "T598-", - "T599-", - "T600-", - "T601-", - "T602-", - "T617-", - "A2237-", - "C2238-", - "G2239-", - "C4693-", - "T4694-", - "T4695-", - "A4696-", - "A4697-", - "C4698-", - "T4699-", - "A4700-", - "A4701-", - "C4702-", - "T4703-", - "T4704-", - "A4705-", - "T4706-", - "G4707-", - "A4708-", - "C4709-", - "T4710-", - "T4711-", - "A4712-", - "A4713-", - "C4714-", - "T4715-", - "A4716-", - "A4717-", - "C4718-", - "T4719-", - "T4720-", - "A4721-", - "T4722-", - "G4723-", - "A4724-", - "C4725-", - "T4726-", - "T4727-", - "A4728-", - "A4729-", - "C4730-", - "T4731-", - "A4732-", - "A4733-", - "C4734-", - "T4735-", - "T4736-", - "A4737-", - "T4738-", - "G4739-", - "A4740-", - "C4741-", - "T4742-", - "T4743-", - "A4744-", - "A4745-", - "C4746-", - "T4747-", - "A4748-", - "A4749-", - "C4750-", - "T4751-", - "T4752-", - "A4753-", - "T4754-", - "G4755-", - "A4756-", - "C4757-", - "T4758-", - "T4759-", - "A4760-", - "A4761-", - "C4762-", - "T4763-", - "A4764-", - "A4765-", - "C4766-", - "T4767-", - "T4768-", - "A4769-", - "T4770-", - "G4771-", - "A4772-", - "C4773-", - "T4774-", - "T4775-", - "C6429-", - "T6430-", - "C7016-", - "T7017-", - "C7018-", - "T7019-", - "C7020-", - "G7021-", - "A7142-", - "T7143-", - "C7144-", - "T7145-", - "T7404-", - "A8048-", - "A8049-", - "T8325-", - "T8326-", - "C8414-", - "A8415-", - "T8416-", - "A8417-", - "T8422C", - "A8471-", - "T8494-", - "T8913-", - "T8992-", - "A9282-", - "A9523-", - "A10275-", - "T10497-", - "A13276-", - "T13352-", - "T15546-", - "A15547-", - "A15867-", - "G16608-", - "T16609-", - "C16610-", - "A16611-", - "T16612-", - "C16613-", - "A18055-", - "C18056-", - "C18057-", - "A21075-", - "A23171T", - "T23172A", - "A23173-", - "A24307-", - "C24336-", - "A27108-", - "A28531-", - "A28532-", - "A28583-", - "T28584-", - "T28585-", - "A28586-", - "T28587-", - "C28588-", - "C28589-", - "A28590-", - "G28591-", - "T28592-", - "G28593-", - "T28594-", - "T28595-", - "A28596-", - "A28597-", - "A28598-", - "A28599-", - "A28600-", - "A28601-", - "T32188-", - "G32209-", - "A32210-", - "C32211-", - "A33193-", - "T33409-", - "T35565-", - "T41738-", - "T41929-", - "A43495-", - "A45117-", - "A46506-", - "C46507-", - "A46508-", - "T46590-", - "T46643-", - "A47573-", - "A47700-", - "C47701-", - "T48162-", - "A48163-", - "G48164-", - "T50499-", - "C50500-", - "T50575-", - "A50576-", - "A57274-", - "A58644-", - "A62034-", - "T62369-", - "T64749-", - "T66777-", - "A66839-", - "A71174-", - "T71896-", - "T76079-", - "T76080-", - "A76883-", - "T80841-", - "T80842-", - "A81968-", - "T87399-", - "T88831-", - "A89100-", - "A91698-", - "T94640-", - "T94641-", - "T97549-", - "T102743-", - "T103362-", - "T105355-", - "C106158-", - "C115266-", - "T116958-", - "T121116-", - "A123988-", - "A124720-", - "A127747-", - "A127748-", - "A128927-", - "G131761-", - "T132811-", - "T133085-", - "T133086-", - "T133087-", - "T133088-", - "T133089-", - "T133090-", - "T133091-", - "T133092-", - "T133093-", - "T133094-", - "T133095-", - "T133096-", - "T133097-", - "T133098-", - "T133099-", - "T133493-", - "C133494-", - "G133495-", - "G133496-", - "T133497-", - "C133498-", - "C133499-", - "A133500-", - "T133501-", - "G133502-", - "T133503-", - "C133504-", - "T133505-", - "C133506-", - "C133507-", - "A133508-", - "T133509-", - "T133510-", - "G133511-", - "C133512-", - "T133513-", - "A133514-", - "C133515-", - "A133516-", - "C133517-", - "C133518-", - "A133519-", - "C133520-", - "C133521-", - "A133522-", - "T133523-", - "T133524-", - "A133525-", - "G133526-", - "A133527-", - "T133528-", - "T133529-", - "T133530-", - "A133531-", - "C133532-", - "A133533-", - "G133534-", - "G133535-", - "C133536-", - "T133537-", - "G133538-", - "C133539-", - "T133540-", - "A133541-", - "G133542-", - "T133543-", - "T133544-", - "G133545-", - "T133546-", - "C133547-", - "G133548-", - "T133549-", - "T133550-", - "C133551-", - "G133552-", - "A133553-", - "G133554-", - "A133555-", - "T133556-", - "C133557-", - "A133558-", - "G133559-", - "A133560-", - "A133561-", - "A133562-", - "T133563-", - "A133564-", - "C133565-", - "G133566-", - "T133567-", - "G133568-", - "T133569-", - "T133570-", - "T133571-", - "T133572-", - "C133573-", - "T133574-", - "T133575-", - "G133576-", - "G133577-", - "A133578-", - "A133579-", - "T133580-", - "G133581-", - "G133582-", - "A133583-", - "T133584-", - "T133585-", - "T133586-", - "C133587-", - "G133588-", - "T133589-", - "C133590-", - "G133591-", - "A133592-", - "T133593-", - "G133594-", - "T133595-", - "A133596-", - "C133597-", - "T133598-", - "T133599-", - "G133600-", - "T133601-", - "C133602-", - "A133603-", - "T133604-", - "G133605-", - "A133606-", - "T133607-", - "T133608-", - "G133609-", - "G133610-", - "C133611-", - "A133612-", - "T133613-", - "C133614-", - "G133615-", - "A133616-", - "A133617-", - "A133618-", - "C133619-", - "A133620-", - "C133621-", - "T133622-", - "T133623-", - "A133624-", - "T133625-", - "T133626-", - "A133627-", - "A133628-", - "G133629-", - "T133630-", - "T133631-", - "C133632-", - "T133633-", - "T133634-", - "T133635-", - "T133636-", - "T133637-", - "T133638-", - "T133639-", - "C133640-", - "A133641-", - "A133642-", - "T133643-", - "T133644-", - "C133645-", - "T133646-", - "A133647-", - "C133648-", - "G133649-", - "A133650-", - "T133651-", - "T133652-", - "T133653-", - "T133654-", - "A133655-", - "T133656-", - "T133657-", - "T133658-", - "C133659-", - "T133660-", - "T133661-", - "T133662-", - "C133663-", - "G133664-", - "C133665-", - "G133666-", - "A133667-", - "G133668-", - "T133669-", - "C133670-", - "A133671-", - "A133672-", - "T133673-", - "T133674-", - "C133675-", - "C133676-", - "C133677-", - "T133678-", - "C133679-", - "C133680-", - "T133681-", - "G133682-", - "T133683-", - "A133684-", - "G133685-", - "T133686-", - "A133687-", - "A133688-", - "C133689-", - "T133690-", - "A133691-", - "T133692-", - "C133693-", - "A133694-", - "G133695-", - "T133696-", - "T133697-", - "T133698-", - "T133699-", - "G133700-", - "T133701-", - "C133702-", - "A133703-", - "G133704-", - "A133705-", - "T133706-", - "T133707-", - "C133708-", - "A133709-", - "C133710-", - "G133711-", - "C133712-", - "T133713-", - "C133714-", - "T133715-", - "C133716-", - "T133717-", - "A133718-", - "C133719-", - "G133720-", - "T133721-", - "A133722-", - "G133723-", - "A133724-", - "C133725-", - "T133726-", - "T133727-", - "T133728-", - "C133729-", - "T133730-", - "T133731-", - "G133732-", - "T133733-", - "A133734-", - "A133735-", - "G133736-", - "T133737-", - "T133738-", - "A133739-", - "C133740-", - "T133741-", - "A133742-", - "A133743-", - "T133744-", - "T133745-", - "T133746-", - "G133747-", - "T133748-", - "T133749-", - "C133750-", - "C133751-", - "C133752-", - "T133753-", - "G133754-", - "G133755-", - "C133756-", - "A133757-", - "T133758-", - "T133759-", - "A133760-", - "C133761-", - "C133762-", - "G133763-", - "A133764-", - "G133765-", - "T133766-", - "T133767-", - "C133768-", - "A133769-", - "G133770-", - "T133771-", - "T133772-", - "T133773-", - "T133774-", - "A133775-", - "T133776-", - "A133777-", - "T133778-", - "G133779-", - "C133780-", - "C133781-", - "G133782-", - "A133783-", - "A133784-", - "T133785-", - "A133786-", - "G133787-", - "A133788-", - "G133789-", - "T133790-", - "T133791-", - "C133792-", - "T133793-", - "G133794-", - "A133795-", - "T133796-", - "T133797-", - "C133798-", - "A133799-", - "T133800-", - "C133801-", - "C133802-", - "T133803-", - "T133804-", - "T133805-", - "G133806-", - "A133807-", - "G133808-", - "A133809-", - "A133810-", - "G133811-", - "A133812-", - "T133813-", - "C133814-", - "T133815-", - "C133816-", - "T133817-", - "A133818-", - "G133819-", - "C133820-", - "G133821-", - "A133822-", - "T133823-", - "C133824-", - "G133825-", - "T133826-", - "T133827-", - "C133828-", - "A133829-", - "A133830-", - "G133831-", - "A133832-", - "T133833-", - "C133834-", - "C133835-", - "C133836-", - "T133837-", - "G133838-", - "A133839-", - "T133840-", - "T133841-", - "C133842-", - "T133843-", - "A133844-", - "G133845-", - "T133846-", - "C133847-", - "T133848-", - "T133849-", - "T133850-", - "A133851-", - "G133852-", - "C133853-", - "C133854-", - "T133855-", - "A133856-", - "T133857-", - "T133858-", - "T133859-", - "A133860-", - "C133861-", - "C133862-", - "T133863-", - "C133864-", - "C133865-", - "T133866-", - "C133867-", - "A133868-", - "G133869-", - "A133870-", - "A133871-", - "G133872-", - "A133873-", - "T133874-", - "G133875-", - "C133876-", - "T133877-", - "C133878-", - "C133879-", - "G133880-", - "T133881-", - "T133882-", - "A133883-", - "C133884-", - "C133885-", - "G133886-", - "T133887-", - "T133888-", - "T133889-", - "T133890-", - "T133891-", - "A133892-", - "C133893-", - "A133894-", - "A133895-", - "T133896-", - "C133897-", - "G133898-", - "T133899-", - "T133900-", - "A133901-", - "A133902-", - "G133903-", - "A133904-", - "T133905-", - "G133906-", - "T133907-", - "C133908-", - "T133909-", - "A133910-", - "T133911-", - "C133912-", - "A133913-", - "A133914-", - "G133915-", - "A133916-", - "T133917-", - "C133918-", - "C133919-", - "A133920-", - "T133921-", - "G133922-", - "A133923-", - "T133924-", - "T133925-", - "C133926-", - "T133927-", - "A133928-", - "T133929-", - "C133930-", - "T133931-", - "C133932-", - "T133933-", - "T133934-", - "T133935-", - "T133936-", - "C133937-", - "C133938-", - "A133939-", - "T133940-", - "A133941-", - "T133942-", - "C133943-", - "A133944-", - "G133945-", - "T137881-", - "A138468-", - "T139424-", - "G139425-", - "T139426-", - "A140105-", - "T140106-", - "A140107-", - "A140108-", - "C140109-", - "A140110-", - "A140111-", - "T140112-", - "T140113-", - "A142752-", - "G143458-", - "A145892-", - "T145976-", - "A145977-", - "A145978-", - "C146084-", - "G146085-", - "T146127-", - "T146860-", - "A146861-", - "T146869-", - "A146870-", - "T146871-", - "T146872-", - "T146873-", - "T146874-", - "A146875-", - "T146876-", - "A146877-", - "T146878-", - "T146879-", - "T146880-", - "A146964-", - "A148136-", - "A148206-", - "T148337-", - "T150532-", - "A151015-", - "T151016-", - "G151017-", - "A151018-", - "C151019-", - "A151042-", - "T152265-", - "T152266-", - "A152267-", - "A152668-", - "A152669-", - "A153418-", - "T154351-", - "C154352-", - "T155417-", - "A156206-", - "T156370-", - "T156371-", - "A156372-", - "C156373-", - "T156374-", - "G156375-", - "A156376-", - "C156377-", - "T156378-", - "A156379-", - "C156380-", - "A156381-", - "T156382-", - "G156383-", - "T156384-", - "A156385-", - "C156386-", - "T156387-", - "A156388-", - "T156389-", - "T156390-", - "T156391-", - "T156392-", - "A156393-", - "C156394-", - "A156395-", - "T156396-", - "T156397-", - "A156398-", - "C156399-", - "T156400-", - "A156401-", - "C156402-", - "A156403-", - "T156404-", - "T156405-", - "G156406-", - "G156407-", - "C156408-", - "T156409-", - "A156410-", - "C156411-", - "G156412-", - "G156413-", - "C156414-", - "A156415-", - "T156416-", - "A156417-", - "T156418-", - "A156419-", - "T156420-", - "A156421-", - "C156422-", - "C156423-", - "T156424-", - "A156425-", - "T156426-", - "T156427-", - "T156428-", - "C156429-", - "G156430-", - "T156431-", - "C156432-", - "A156433-", - "C156434-", - "T156435-", - "T156436-", - "C156437-", - "C156438-", - "A156439-", - "C156440-", - "A156441-", - "C156442-", - "G156443-", - "C156444-", - "T156445-", - "C156446-", - "C156447-", - "G156448-", - "G156449-", - "T156450-", - "A156451-", - "A156452-", - "A156453-", - "C156454-", - "G156455-", - "G156456-", - "G156457-", - "T156458-", - "G156459-", - "T156460-", - "C156461-", - "A156462-", - "T156463-", - "G156464-", - "T156465-", - "G156466-", - "A156467-", - "C156468-", - "G156469-", - "A156470-", - "G156471-", - "G156472-", - "G156473-", - "A156474-", - "G156475-", - "A156476-", - "A156477-", - "T156478-", - "C156479-", - "T156480-", - "T156481-", - "G156482-", - "A156483-", - "T156484-", - "A156485-", - "A156486-", - "G156487-", - "A156488-", - "G156489-", - "G156490-", - "C156491-", - "A156492-", - "T156493-", - "A156494-", - "A156495-", - "T156496-", - "C156497-", - "A156498-", - "A156499-", - "T156500-", - "G156501-", - "T156502-", - "T156503-", - "G156504-", - "T156505-", - "A156506-", - "A156507-", - "T156508-", - "C156509-", - "C156510-", - "G156511-", - "A156512-", - "T156513-", - "G156514-", - "T156515-", - "C156516-", - "C156517-", - "A156518-", - "C156519-", - "C156520-", - "T156521-", - "G156522-", - "G156523-", - "A156524-", - "G156525-", - "A156526-", - "A156527-", - "T156528-", - "T156529-", - "T156530-", - "G156531-", - "C156532-", - "C156533-", - "A156534-", - "A156535-", - "G156536-", - "G156537-", - "T156538-", - "C156539-", - "A156540-", - "G156541-", - "A156542-", - "T156543-", - "G156544-", - "T156545-", - "A156546-", - "G156547-", - "A156548-", - "G156549-", - "T156550-", - "T156551-", - "G156552-", - "G156553-", - "T156554-", - "A156555-", - "G156556-", - "T156557-", - "G156558-", - "A156559-", - "T156560-", - "A156561-", - "A156562-", - "C156563-", - "A156564-", - "C156565-", - "A156566-", - "A156567-", - "A156568-", - "A156569-", - "T156570-", - "G156571-", - "T156572-", - "G156573-", - "A156574-", - "A156575-", - "C156576-", - "A156577-", - "C156578-", - "T156579-", - "G156580-", - "C156581-", - "C156582-", - "C156583-", - "A156584-", - "C156585-", - "C156586-", - "T156587-", - "C156588-", - "A156589-", - "T156590-", - "A156591-", - "C156592-", - "A156593-", - "T156594-", - "A156595-", - "T156596-", - "A156597-", - "C156598-", - "C156599-", - "G156600-", - "C156601-", - "A156602-", - "A156603-", - "T156604-", - "C156605-", - "C156606-", - "C156607-", - "C156608-", - "A156609-", - "A156610-", - "T156611-", - "T156612-", - "A156613-", - "T156614-", - "T156615-", - "C156616-", - "T156617-", - "A156618-", - "A156619-", - "T156620-", - "A156621-", - "G156622-", - "A156623-", - "T156624-", - "G156625-", - "T156626-", - "C156627-", - "A156628-", - "T156629-", - "C156630-", - "A156631-", - "A156632-", - "T156633-", - "G156634-", - "T156635-", - "A156636-", - "G156637-", - "A156638-", - "A156639-", - "A156640-", - "A156641-", - "T156642-", - "G156643-", - "C156644-", - "C156645-", - "C156646-", - "A156647-", - "A156648-", - "C156649-", - "A156650-", - "G156651-", - "G156652-", - "A156653-", - "T156654-", - "C156655-", - "A156656-", - "T156657-", - "T156658-", - "T156659-", - "G156660-", - "A156661-", - "T156662-", - "A156663-", - "A156664-", - "G156665-", - "G156666-", - "T156667-", - "A156668-", - "A156669-", - "A156670-", - "G156671-", - "T156672-", - "G156673-", - "T156674-", - "A156675-", - "C156676-", - "C156677-", - "G156678-", - "G156679-", - "A156680-", - "A156681-", - "C156682-", - "A156683-", - "C156684-", - "A156685-", - "G156686-", - "A156687-", - "A156688-", - "C156689-", - "A156690-", - "A156691-", - "A156692-", - "T156693-", - "G156694-", - "T156695-", - "T156696-", - "C156697-", - "G156698-", - "T156699-", - "G156700-", - "T156701-", - "C156702-", - "A156703-", - "T156704-", - "C156705-", - "C156706-", - "T156707-", - "G156708-", - "G156709-", - "T156710-", - "T156711-", - "G156712-", - "G156713-", - "T156714-", - "A156715-", - "T156716-", - "A156717-", - "C156718-", - "G156719-", - "C156720-", - "T156721-", - "A156722-", - "C156723-", - "T156724-", - "G156725-", - "A156726-", - "T156727-", - "T156728-", - "C156729-", - "T156730-", - "T156731-", - "C156732-", - "A156733-", - "C156734-", - "A156735-", - "G156736-", - "A156737-", - "C156738-", - "T156739-", - "G156740-", - "A156741-", - "A156742-", - "G156743-", - "A156744-", - "T156745-", - "T156746-", - "G156747-", - "T156748-", - "C156749-", - "G156750-", - "A156751-", - "G156752-", - "A156753-", - "T156754-", - "T156755-", - "T156756-", - "G156757-", - "T156758-", - "G156759-", - "T156760-", - "A156761-", - "C156762-", - "C156763-", - "A156764-", - "A156765-", - "A156766-", - "A156767-", - "A156768-", - "A156769-", - "G156770-", - "G156771-", - "A156772-", - "G156773-", - "A156774-", - "T156775-", - "G156776-", - "T156777-", - "C156778-", - "C156779-", - "A156780-", - "T156781-", - "G156782-", - "C156783-", - "G156784-", - "G156785-", - "A156786-", - "T156787-", - "A156788-", - "C156789-", - "T156790-", - "T156791-", - "T156792-", - "G156793-", - "G156794-", - "T156795-", - "G156796-", - "G156797-", - "A156798-", - "A156799-", - "T156800-", - "A156801-", - "G156802-", - "A156803-", - "T156804-", - "G156805-", - "A156806-", - "A156807-", - "G156808-", - "G156809-", - "A156810-", - "A156811-", - "A156812-", - "T156813-", - "C156814-", - "C156815-", - "T156816-", - "A156817-", - "T156818-", - "T156819-", - "T156820-", - "G156821-", - "T156822-", - "A156823-", - "A156824-", - "A156825-", - "T156826-", - "C156827-", - "G156828-", - "T156829-", - "G156830-", - "T156831-", - "T156832-", - "G156833-", - "T156834-", - "G156835-", - "T156836-", - "T156837-", - "G156838-", - "G156839-", - "T156840-", - "G156841-", - "A156842-", - "A156843-", - "T156844-", - "A156845-", - "T156846-", - "T156847-", - "G156848-", - "C156849-", - "G156850-", - "A156851-", - "C156852-", - "T156853-", - "A156854-", - "C156855-", - "C156856-", - "T156857-", - "A156858-", - "C156859-", - "G156860-", - "T156861-", - "A156862-", - "A156863-", - "T156864-", - "T156865-", - "A156866-", - "T156867-", - "A156868-", - "G156869-", - "A156870-", - "C156871-", - "T156872-", - "T156873-", - "G156874-", - "A156875-", - "T156876-", - "C156877-", - "C156878-", - "A156879-", - "T156880-", - "T156881-", - "T156882-", - "C156883-", - "C156884-", - "T156885-", - "C156886-", - "C156887-", - "A156888-", - "T156889-", - "G156890-", - "C156891-", - "A156892-", - "A156893-", - "A156894-", - "C156895-", - "T156896-", - "A156897-", - "T156898-", - "C156899-", - "T156900-", - "A156901-", - "T156902-", - "C156903-", - "T156904-", - "A156905-", - "A156906-", - "A156907-", - "T156908-", - "G156909-", - "T156910-", - "A156911-", - "A156912-", - "T156913-", - "T156914-", - "A156915-", - "A156916-", - "T156917-", - "T156918-", - "A156919-", - "T156920-", - "G156921-", - "A156922-", - "T156923-", - "T156924-", - "T156925-", - "T156926-", - "G156927-", - "A156928-", - "T156929-", - "G156930-", - "A156931-", - "T156932-", - "A156933-", - "A156934-", - "T156935-", - "G156936-", - "T156937-", - "T156938-", - "A156939-", - "C156940-", - "C156941-", - "A156942-", - "T156943-", - "A156944-", - "C156945-", - "A156946-", - "T156947-", - "T156948-", - "A156949-", - "T156950-", - "A156951-", - "T156952-", - "C156953-", - "A156954-", - "C156955-", - "T156956-", - "A156957-", - "C156958-", - "T156959-", - "T156960-", - "G156961-", - "G156962-", - "T156963-", - "T156964-", - "A156965-", - "G156966-", - "T156967-", - "G156968-", - "T156969-", - "G156970-", - "T156971-", - "A156972-", - "T156973-", - "T156974-", - "A156975-", - "T156976-", - "T156977-", - "T156978-", - "A156979-", - "G156980-", - "T156981-", - "A156982-", - "T156983-", - "G156984-", - "G156985-", - "A156986-", - "A156987-", - "G156988-", - "A156989-", - "C156990-", - "C156991-", - "T156992-", - "A156993-", - "T156994-", - "T156995-", - "A156996-", - "A156997-", - "T156998-", - "A156999-", - "A157000-", - "T157001-", - "T157002-", - "A157003-", - "C157004-", - "T157005-", - "T157006-", - "A157007-", - "T157008-", - "C157009-", - "T157010-", - "T157011-", - "T157012-", - "T157013-", - "G157014-", - "A157015-", - "C157016-", - "G157017-", - "A157018-", - "T157019-", - "C157020-", - "T157021-", - "T157022-", - "G157023-", - "T157024-", - "T157025-", - "A157026-", - "T157027-", - "A157028-", - "A157029-", - "T157030-", - "T157031-", - "A157032-", - "T157033-", - "A157034-", - "A157035-", - "T157036-", - "A157037-", - "T157038-", - "A157039-", - "A157040-", - "A157041-", - "A157042-", - "A157043-", - "T157044-", - "A157045-", - "C157046-", - "T157047-", - "T157048-", - "A157049-", - "T157050-", - "G157051-", - "A157052-", - "C157053-", - "A157054-", - "T157055-", - "A157056-", - "G157057-", - "T157058-", - "A157059-", - "A157060-", - "C157061-", - "T157062-", - "C157063-", - "A157064-", - "T157065-", - "A157066-", - "A157067-", - "T157068-", - "T157069-", - "G157070-", - "C157071-", - "T157072-", - "G157073-", - "A157074-", - "C157075-", - "G157076-", - "C157077-", - "G157078-", - "A157079-", - "T157080-", - "A157081-", - "A157082-", - "A157083-", - "T157084-", - "T157085-", - "C157086-", - "G157087-", - "T157088-", - "A157089-", - "A157090-", - "T157091-", - "A157092-", - "A157093-", - "T157094-", - "C157095-", - "T157096-", - "G157097-", - "T157098-", - "T157099-", - "T157100-", - "T157101-", - "G157102-", - "T157103-", - "T157104-", - "C157105-", - "A157106-", - "A157107-", - "A157108-", - "T157109-", - "T157110-", - "T157111-", - "T157112-", - "T157113-", - "A157114-", - "T157115-", - "A157116-", - "A157117-", - "G157118-", - "G157119-", - "A157120-", - "A157121-", - "T157122-", - "C157123-", - "T157124-", - "A157125-", - "C157126-", - "A157127-", - "G157128-", - "G157129-", - "C157130-", - "A157131-", - "T157132-", - "A157133-", - "A157134-", - "A157135-", - "A157136-", - "A157137-", - "T157138-", - "A157139-", - "A157140-", - "A157141-", - "A157142-", - "A157143-", - "T157144-", - "A157145-", - "T157146-", - "A157147-", - "A157148-", - "T157149-", - "C157150-", - "T157151-", - "A157152-", - "T157153-", - "A157154-", - "A157155-", - "T157156-", - "A157157-", - "T157158-", - "A157159-", - "C157160-", - "T157161-", - "C157162-", - "T157163-", - "T157164-", - "A157165-", - "C157166-", - "A157167-", - "A157168-", - "C157169-", - "G157170-", - "C157171-", - "C157172-", - "A157173-", - "T157174-", - "C157175-", - "A157176-", - "T157177-", - "G157178-", - "A157179-", - "A157180-", - "T157181-", - "A157182-", - "G157183-", - "C157184-", - "A157185-", - "G157186-", - "T157187-", - "G157188-", - "A157189-", - "A157190-", - "T157191-", - "T157192-", - "A157193-", - "A157194-", - "T157195-", - "T157196-", - "G157197-", - "C157198-", - "T157199-", - "G157200-", - "T157201-", - "T157202-", - "A157203-", - "T157204-", - "T157205-", - "A157206-", - "T157207-", - "G157208-", - "G157209-", - "A157210-", - "T157211-", - "T157212-", - "T157213-", - "A157214-", - "G157215-", - "A157216-", - "A157217-", - "A157218-", - "T157219-", - "A157220-", - "G157221-", - "T157222-", - "G157223-", - "G157224-", - "A157225-", - "C157226-", - "G157227-", - "A157228-", - "T157229-", - "T157230-", - "T157231-", - "T157232-", - "G157233-", - "T157234-", - "G157235-", - "A157236-", - "T157237-", - "A157238-", - "T157239-", - "T157240-", - "A157241-", - "A157242-", - "T157243-", - "A157244-", - "T157245-", - "A157246-", - "G157247-", - "T157248-", - "T157249-", - "A157250-", - "T157251-", - "T157252-", - "A157253-", - "A157254-", - "T157255-", - "G157256-", - "A157257-", - "T157258-", - "G157259-", - "A157260-", - "A157261-", - "A157262-", - "G157263-", - "G157264-", - "A157265-", - "T157266-", - "A157267-", - "A157268-", - "A157269-", - "C157270-", - "G157271-", - "C157272-", - "G157273-", - "C157274-", - "A157275-", - "T157276-", - "A157277-", - "G157278-", - "A157279-", - "C157280-", - "T157281-", - "C157282-", - "A157283-", - "T157284-", - "C157285-", - "C157286-", - "T157287-", - "A157288-", - "T157289-", - "C157290-", - "T157291-", - "G157292-", - "G157293-", - "A157294-", - "G157295-", - "C157296-", - "C157297-", - "T157298-", - "C157299-", - "C157300-", - "G157301-", - "A157302-", - "A157303-", - "T157304-", - "A157305-", - "T157306-", - "T157307-", - "T157308-", - "T157309-", - "T157310-", - "T157311-", - "C157312-", - "C157313-", - "A157314-", - "T157315-", - "T157316-", - "C157317-", - "T157318-", - "G157319-", - "T157320-", - "T157321-", - "T157322-", - "T157323-", - "C157324-", - "C157325-", - "A157326-", - "A157327-", - "T157328-", - "A157329-", - "A157330-", - "T157331-", - "T157332-", - "T157333-", - "T157334-", - "A157335-", - "T157336-", - "C157337-", - "G157338-", - "A157339-", - "T157340-", - "T157341-", - "C157342-", - "T157343-", - "A157344-", - "A157345-", - "T157346-", - "G157347-", - "A157348-", - "A157349-", - "T157350-", - "A157351-", - "C157352-", - "G157353-", - "A157354-", - "A157355-", - "G157356-", - "T157357-", - "T157358-", - "A157359-", - "A157360-", - "T157361-", - "C157362-", - "T157363-", - "A157364-", - "A157365-", - "G157366-", - "T157367-", - "C157368-", - "A157369-", - "T157370-", - "T157371-", - "T157372-", - "A157373-", - "G157374-", - "A157375-", - "T157376-", - "T157377-", - "A157378-", - "T157379-", - "C157380-", - "A157381-", - "A157382-", - "A157383-", - "G157384-", - "T157385-", - "G157386-", - "T157387-", - "T157388-", - "A157389-", - "A157390-", - "C157391-", - "T157392-", - "A157393-", - "T157394-", - "T157395-", - "T157396-", - "G157397-", - "A157398-", - "T157399-", - "C157400-", - "G157401-", - "A157402-", - "T157403-", - "T157404-", - "A157405-", - "C157406-", - "A157407-", - "T157408-", - "T157409-", - "T157410-", - "A157411-", - "T157412-", - "G157413-", - "G157414-", - "G157415-", - "A157416-", - "T157417-", - "A157418-", - "C157419-", - "C157420-", - "T157421-", - "T157422-", - "T157423-", - "G157424-", - "A157425-", - "G157426-", - "C157427-", - "C157428-", - "T157429-", - "A157430-", - "A157431-", - "C157432-", - "T157433-", - "A157434-", - "A157435-", - "C157436-", - "A157437-", - "A157438-", - "T157439-", - "A157440-", - "A157441-", - "C157442-", - "G157443-", - "T157444-", - "G157445-", - "A157446-", - "A157447-", - "A157448-", - "T157449-", - "A157450-", - "T157451-", - "A157452-", - "T157453-", - "T157454-", - "C157455-", - "T157456-", - "T157457-", - "T157458-", - "C157459-", - "A157460-", - "A157461-", - "C157462-", - "C157463-", - "G157464-", - "C157465-", - "T157466-", - "G157467-", - "A157468-", - "T157469-", - "T157470-", - "T157471-", - "T157472-", - "T157473-", - "T157474-", - "T157475-", - "A157476-", - "C157477-", - "A157478-", - "A157479-", - "A157480-", - "T157481-", - "T157482-", - "G157483-", - "G157484-", - "A157485-", - "T157486-", - "C157487-", - "T157488-", - "G157489-", - "T157490-", - "C157491-", - "A157492-", - "T157493-", - "T157494-", - "A157495-", - "C157496-", - "T157497-", - "G157498-", - "A157499-", - "G157500-", - "T157501-", - "G157502-", - "C157503-", - "G157504-", - "A157505-", - "A157506-", - "A157507-", - "A157508-", - "A157509-", - "T157510-", - "A157511-", - "C157512-", - "A157513-", - "T157514-", - "A157515-", - "C157516-", - "T157517-", - "T157518-", - "A157519-", - "A157520-", - "A157521-", - "A157522-", - "A157523-", - "T157524-", - "C157525-", - "T157526-", - "T157527-", - "T157528-", - "G157529-", - "T157530-", - "T157531-", - "T157532-", - "T157533-", - "A157534-", - "G157535-", - "A157536-", - "A157537-", - "A157538-", - "C157539-", - "T157540-", - "G157541-", - "T157542-", - "A157543-", - "T157544-", - "C157545-", - "G157546-", - "A157547-", - "T157548-", - "T157549-", - "T157550-", - "C157551-", - "T157552-", - "A157553-", - "C157554-", - "A157555-", - "T157556-", - "A157557-", - "T157558-", - "A157559-", - "C157560-", - "G157561-", - "C157562-", - "T157563-", - "G157564-", - "A157565-", - "T157566-", - "A157567-", - "A157568-", - "A157569-", - "T157570-", - "A157571-", - "T157572-", - "A157573-", - "A157574-", - "T157575-", - "A157576-", - "A157577-", - "C157578-", - "A157579-", - "A157580-", - "G157581-", - "A157582-", - "A157583-", - "A157584-", - "A157585-", - "T157586-", - "A157587-", - "G157588-", - "A157589-", - "A157590-", - "T157591-", - "T157592-", - "A157593-", - "G157594-", - "C157595-", - "A157596-", - "T157597-", - "C157598-", - "G157599-", - "T157600-", - "T157601-", - "T157602-", - "A157603-", - "A157604-", - "C157605-", - "A157606-", - "C157607-", - "A157608-", - "A157609-", - "T157610-", - "A157611-", - "T157612-", - "T157613-", - "A157614-", - "C157615-", - "G157616-", - "A157617-", - "A157618-", - "A157619-", - "T157620-", - "A157621-", - "T157622-", - "T157623-", - "T157624-", - "T157625-", - "G157626-", - "A157627-", - "G157628-", - "A157629-", - "C157630-", - "T157631-", - "C157632-", - "A157633-", - "T157634-", - "C157635-", - "A157636-", - "A157637-", - "C157638-", - "A157639-", - "A157640-", - "T157641-", - "G157642-", - "A157643-", - "A157644-", - "A157645-", - "A157646-", - "C157647-", - "T157648-", - "T157649-", - "T157650-", - "A157651-", - "A157652-", - "A157653-", - "T157654-", - "A157655-", - "C157656-", - "T157657-", - "T157658-", - "A157659-", - "A157660-", - "C157661-", - "A157662-", - "G157663-", - "A157664-", - "G157665-", - "G157666-", - "A157667-", - "A157668-", - "T157669-", - "C157670-", - "A157671-", - "A157672-", - "T157673-", - "G157674-", - "A157675-", - "T157676-", - "A157677-", - "A157678-", - "A157679-", - "A157680-", - "A157681-", - "T157682-", - "T157683-", - "T157684-", - "T157685-", - "A157686-", - "A157687-", - "G157688-", - "C157689-", - "G157690-", - "A157691-", - "T157692-", - "G157693-", - "A157694-", - "T157695-", - "A157696-", - "T157697-", - "G157698-", - "T157699-", - "T157700-", - "A157701-", - "T157702-", - "A157703-", - "T157704-", - "A157705-", - "T157706-", - "A157707-", - "A157708-", - "A157709-", - "A157710-", - "A157711-", - "A157712-", - "T157713-", - "G157714-", - "A157715-", - "G157716-", - "G157717-", - "A157718-", - "T157719-", - "T157720-", - "T157721-", - "C157722-", - "A157723-", - "C157724-", - "C157725-", - "C157726-", - "C157727-", - "A157728-", - "C157729-", - "T157730-", - "G157731-", - "A157732-", - "T157733-", - "T157734-", - "C157735-", - "T157736-", - "C157737-", - "A157738-", - "T157739-", - "T157740-", - "A157741-", - "A157742-", - "A157743-", - "T157744-", - "G157745-", - "G157746-", - "T157747-", - "T157748-", - "A157749-", - "G157750-", - "A157751-", - "G157752-", - "A157753-", - "G157754-", - "T157755-", - "A157756-", - "C157757-", - "A157758-", - "C157759-", - "C157760-", - "A157761-", - "A157762-", - "C157763-", - "C157764-", - "A157765-", - "T157766-", - "G157767-", - "T157768-", - "A157769-", - "C157770-", - "C157771-", - "G157772-", - "T157773-", - "C157774-", - "G157775-", - "A157776-", - "G157777-", - "T157778-", - "T157779-", - "A157780-", - "C157781-", - "T157782-", - "T157783-", - "A157784-", - "G157785-", - "A157786-", - "T157787-", - "G157788-", - "C157789-", - "C157790-", - "T157791-", - "C157792-", - "A157793-", - "G157794-", - "A157795-", - "A157796-", - "T157797-", - "A157798-", - "T157799-", - "C157800-", - "A157801-", - "T157802-", - "T157803-", - "T157804-", - "C157805-", - "T157806-", - "T157807-", - "T157808-", - "C157809-", - "C157810-", - "C157811-", - "C157812-", - "A157813-", - "C157814-", - "A157815-", - "A157816-", - "G157817-", - "T157818-", - "T157819-", - "A157820-", - "T157821-", - "A157822-", - "A157823-", - "A157824-", - "A157825-", - "T157826-", - "C157827-", - "A157828-", - "C157829-", - "T157830-", - "T157831-", - "T157832-", - "A157833-", - "T157834-", - "A157835-", - "G157836-", - "T157837-", - "C157838-", - "A157839-", - "T157840-", - "C157841-", - "G157842-", - "A157843-", - "C157844-", - "T157845-", - "G157846-", - "G157847-", - "T157848-", - "T157849-", - "A157850-", - "G157851-", - "T157852-", - "T157853-", - "C157854-", - "A157855-", - "A157856-", - "T157857-", - "C157858-", - "T157859-", - "A157860-", - "C157861-", - "G157862-", - "A157863-", - "A157864-", - "T157865-", - "G157866-", - "T157867-", - "A157868-", - "T157869-", - "A157870-", - "A157871-", - "C157872-", - "A157873-", - "T157874-", - "T157875-", - "C157876-", - "T157877-", - "T157878-", - "A157879-", - "A157880-", - "A157881-", - "C157882-", - "A157883-", - "A157884-", - "T157885-", - "A157886-", - "T157887-", - "A157888-", - "G157889-", - "C157890-", - "A157891-", - "T157892-", - "T157893-", - "C157894-", - "T157895-", - "T157896-", - "G157897-", - "G157898-", - "A157899-", - "T157900-", - "A157901-", - "A157902-", - "A157903-", - "T157904-", - "C157905-", - "A157906-", - "T157907-", - "T157908-", - "T157909-", - "C157910-", - "C157911-", - "T157912-", - "A157913-", - "G157914-", - "A157915-", - "T157916-", - "A157917-", - "C157918-", - "C157919-", - "A157920-", - "T157921-", - "A157922-", - "T157923-", - "C157924-", - "A157925-", - "T157926-", - "C157927-", - "G157928-", - "A157929-", - "G157930-", - "T157931-", - "T157932-", - "G157933-", - "A157934-", - "T157935-", - "A157936-", - "T157937-", - "C157938-", - "T157939-", - "A157940-", - "T157941-", - "C157942-", - "G157943-", - "G157944-", - "T157945-", - "A157946-", - "T157947-", - "A157948-", - "A157949-", - "G157950-", - "T157951-", - "A157952-", - "A157953-", - "T157954-", - "T157955-", - "C157956-", - "A157957-", - "C157958-", - "A157959-", - "T157960-", - "G157961-", - "A157962-", - "T157963-", - "A157964-", - "A157965-", - "G157966-", - "A157967-", - "T157968-", - "T157969-", - "T157970-", - "C157971-", - "C157972-", - "A157973-", - "T157974-", - "A157975-", - "A157976-", - "A157977-", - "C157978-", - "T157979-", - "G157980-", - "C157981-", - "T157982-", - "A157983-", - "C157984-", - "A157985-", - "A157986-", - "T157987-", - "C157988-", - "A157989-", - "T157990-", - "A157991-", - "A157992-", - "A157993-", - "A157994-", - "A157995-", - "A157996-", - "A157997-", - "T157998-", - "T157999-", - "C158000-", - "A158001-", - "T158002-", - "G158003-", - "G158004-", - "G158005-", - "A158006-", - "A158007-", - "A158008-", - "T158009-", - "G158010-", - "A158011-", - "T158012-", - "A158013-", - "T158014-", - "C158015-", - "T158016-", - "T158017-", - "C158018-", - "A158019-", - "C158020-", - "G158021-", - "T158022-", - "A158023-", - "G158024-", - "A158025-", - "T158026-", - "A158027-", - "T158028-", - "A158029-", - "G158030-", - "G158031-", - "T158032-", - "G158033-", - "T158034-", - "A158035-", - "G158036-", - "T158037-", - "T158038-", - "T158039-", - "C158040-", - "G158041-", - "C158042-", - "A158043-", - "G158044-", - "T158045-", - "G158046-", - "A158047-", - "C158048-", - "C158049-", - "G158050-", - "T158051-", - "C158052-", - "C158053-", - "T158054-", - "G158055-", - "G158056-", - "A158057-", - "T158058-", - "A158059-", - "A158060-", - "T158061-", - "A158062-", - "T158063-", - "T158064-", - "A158065-", - "T158066-", - "C158067-", - "T158068-", - "A158069-", - "T158070-", - "A158071-", - "T158072-", - "G158073-", - "A158074-", - "T158075-", - "G158076-", - "G158077-", - "G158078-", - "T158079-", - "G158080-", - "G158081-", - "A158082-", - "T158083-", - "A158084-", - "T158085-", - "G158086-", - "A158087-", - "T158088-", - "C158089-", - "A158090-", - "G158091-", - "T158092-", - "C158093-", - "C158094-", - "C158095-", - "T158096-", - "G158097-", - "T158098-", - "A158099-", - "T158100-", - "A158101-", - "G158102-", - "A158103-", - "A158104-", - "G158105-", - "T158106-", - "T158107-", - "C158108-", - "A158109-", - "A158110-", - "A158111-", - "G158112-", - "G158113-", - "T158114-", - "T158115-", - "A158116-", - "T158117-", - "A158118-", - "G158119-", - "C158120-", - "G158121-", - "T158122-", - "A158123-", - "C158124-", - "A158125-", - "A158126-", - "T158127-", - "A158128-", - "C158129-", - "A158130-", - "T158131-", - "G158132-", - "T158133-", - "A158134-", - "C158135-", - "T158136-", - "A158137-", - "A158138-", - "T158139-", - "T158140-", - "C158141-", - "T158142-", - "T158143-", - "G158144-", - "G158145-", - "A158146-", - "T158147-", - "A158148-", - "T158149-", - "A158150-", - "T158151-", - "G158152-", - "A158153-", - "T158154-", - "A158155-", - "T158156-", - "A158157-", - "C158158-", - "C158159-", - "A158160-", - "G158161-", - "A158162-", - "G158163-", - "C158164-", - "T158165-", - "A158166-", - "A158167-", - "A158168-", - "A158169-", - "A158170-", - "T158171-", - "A158172-", - "T158173-", - "C158174-", - "A158175-", - "T158176-", - "C158177-", - "G158178-", - "T158179-", - "T158180-", - "C158181-", - "T158182-", - "A158183-", - "A158184-", - "T158185-", - "T158186-", - "G158187-", - "C158188-", - "G158189-", - "G158190-", - "A158191-", - "G158192-", - "G158193-", - "A158194-", - "G158195-", - "T158196-", - "T158197-", - "G158198-", - "C158199-", - "C158200-", - "A158201-", - "A158202-", - "T158203-", - "G158204-", - "A158205-", - "C158206-", - "G158207-", - "A158208-", - "A158209-", - "T158210-", - "A158211-", - "C158212-", - "A158213-", - "T158214-", - "T158215-", - "T158216-", - "A158217-", - "T158218-", - "T158219-", - "G158220-", - "T158221-", - "A158222-", - "T158223-", - "A158224-", - "G158225-", - "G158226-", - "C158227-", - "G158228-", - "G158229-", - "T158230-", - "A158231-", - "T158232-", - "A158233-", - "C158234-", - "G158235-", - "C158236-", - "G158237-", - "A158238-", - "T158239-", - "C158240-", - "A158241-", - "G158242-", - "G158243-", - "A158244-", - "G158245-", - "T158246-", - "C158247-", - "A158248-", - "T158249-", - "C158250-", - "G158251-", - "T158252-", - "T158253-", - "G158254-", - "A158255-", - "T158256-", - "A158257-", - "T158258-", - "C158259-", - "T158260-", - "A158261-", - "G158262-", - "T158263-", - "A158264-", - "T158265-", - "C158266-", - "G158267-", - "A158268-", - "T158269-", - "A158270-", - "G158271-", - "A158272-", - "T158273-", - "G158274-", - "G158275-", - "A158276-", - "A158277-", - "G158278-", - "C158279-", - "C158280-", - "A158281-", - "T158282-", - "C158283-", - "A158284-", - "A158285-", - "A158286-", - "A158287-", - "C158288-", - "C158289-", - "A158290-", - "T158291-", - "A158292-", - "T158293-", - "T158294-", - "G158295-", - "G158296-", - "C158297-", - "A158298-", - "G158299-", - "A158300-", - "A158301-", - "G158302-", - "T158303-", - "A158304-", - "T158305-", - "G158306-", - "C158307-", - "T158308-", - "A158309-", - "A158310-", - "A158311-", - "A158312-", - "T158313-", - "G158314-", - "T158315-", - "G158316-", - "C158317-", - "G158318-", - "A158319-", - "A158320-", - "C158321-", - "C158322-", - "A158323-", - "A158324-", - "A158325-", - "A158326-", - "T158327-", - "G158328-", - "T158329-", - "G158330-", - "A158331-", - "T158332-", - "A158333-", - "T158334-", - "G158335-", - "G158336-", - "G158337-", - "G158338-", - "T158339-", - "T158340-", - "G158341-", - "C158342-", - "G158343-", - "A158344-", - "T158345-", - "T158346-", - "T158347-", - "T158348-", - "A158349-", - "A158350-", - "A158351-", - "C158352-", - "G158353-", - "G158354-", - "A158355-", - "T158356-", - "T158357-", - "A158358-", - "A158359-", - "T158360-", - "A158361-", - "T158362-", - "A158363-", - "T158364-", - "G158365-", - "T158366-", - "C158367-", - "A158368-", - "T158369-", - "A158370-", - "G158371-", - "G158372-", - "T158373-", - "G158374-", - "G158375-", - "A158376-", - "G158377-", - "T158378-", - "C158379-", - "G158380-", - "T158381-", - "T158382-", - "A158383-", - "A158384-", - "A158385-", - "G158386-", - "G158387-", - "T158388-", - "G158389-", - "A158390-", - "C158391-", - "A158392-", - "C158393-", - "A158394-", - "C158395-", - "A158396-", - "T158397-", - "A158398-", - "T158399-", - "A158400-", - "C158401-", - "C158402-", - "A158403-", - "A158404-", - "C158405-", - "G158406-", - "C158407-", - "A158408-", - "C158409-", - "T158410-", - "A158411-", - "G158412-", - "A158413-", - "G158414-", - "A158415-", - "G158416-", - "T158417-", - "T158418-", - "T158419-", - "A158420-", - "T158421-", - "C158422-", - "A158423-", - "G158424-", - "A158425-", - "A158426-", - "G158427-", - "A158428-", - "T158429-", - "G158430-", - "G158431-", - "A158432-", - "T158433-", - "G158434-", - "G158435-", - "A158436-", - "T158437-", - "G158438-", - "A158439-", - "A158440-", - "T158441-", - "C158442-", - "A158443-", - "T158444-", - "C158445-", - "A158446-", - "A158447-", - "C158448-", - "G158449-", - "T158450-", - "C158451-", - "T158452-", - "T158453-", - "C158454-", - "C158455-", - "A158456-", - "A158457-", - "T158458-", - "A158459-", - "A158460-", - "A158461-", - "A158462-", - "A158463-", - "T158464-", - "G158465-", - "T158466-", - "C158467-", - "C158468-", - "A158469-", - "A158470-", - "T158471-", - "A158472-", - "T158473-", - "G158474-", - "T158475-", - "C158476-", - "G158477-", - "A158478-", - "C158479-", - "G158480-", - "A158481-", - "T158482-", - "T158483-", - "G158484-", - "T158485-", - "T158486-", - "C158487-", - "A158488-", - "T158489-", - "G158490-", - "C158491-", - "T158492-", - "G158493-", - "G158494-", - "A158495-", - "A158496-", - "A158497-", - "G158498-", - "A158499-", - "T158500-", - "T158501-", - "T158502-", - "A158503-", - "T158504-", - "A158505-", - "T158506-", - "A158507-", - "T158508-", - "C158509-", - "T158510-", - "A158511-", - "G158512-", - "A158513-", - "G158514-", - "G158515-", - "T158516-", - "T158517-", - "A158518-", - "C158519-", - "A158520-", - "A158521-", - "C158522-", - "A158523-", - "A158524-", - "T158525-", - "A158526-", - "G158527-", - "T158528-", - "A158529-", - "G158530-", - "T158531-", - "G158532-", - "T158533-", - "A158534-", - "G158535-", - "T158536-", - "T158537-", - "A158538-", - "A158539-", - "T158540-", - "G158541-", - "T158542-", - "A158543-", - "A158544-", - "T158545-", - "A158546-", - "T158547-", - "C158548-", - "G158549-", - "A158550-", - "A158551-", - "T158552-", - "C158553-", - "T158554-", - "A158555-", - "G158556-", - "T158557-", - "C158558-", - "C158559-", - "T158560-", - "T158561-", - "A158562-", - "G158563-", - "C158564-", - "T158565-", - "A158566-", - "T158567-", - "A158568-", - "A158569-", - "T158570-", - "C158571-", - "C158572-", - "G158573-", - "A158574-", - "T158575-", - "A158576-", - "T158577-", - "A158578-", - "T158579-", - "G158580-", - "A158581-", - "T158582-", - "G158583-", - "A158584-", - "A158585-", - "T158586-", - "G158587-", - "G158588-", - "A158589-", - "C158590-", - "C158591-", - "A158592-", - "A158593-", - "A158594-", - "T158595-", - "T158596-", - "A158597-", - "T158598-", - "C158599-", - "A158600-", - "T158601-", - "C158602-", - "A158603-", - "T158604-", - "T158605-", - "A158606-", - "A158607-", - "A158608-", - "T158609-", - "A158610-", - "T158611-", - "T158612-", - "C158613-", - "C158614-", - "T158615-", - "A158616-", - "G158617-", - "A158618-", - "A158619-", - "T158620-", - "T158621-", - "A158622-", - "A158623-", - "T158624-", - "C158625-", - "C158626-", - "T158627-", - "G158628-", - "C158629-", - "T158630-", - "C158631-", - "T158632-", - "A158633-", - "G160043-", - "A162901-", - "T163190-", - "A163191-", - "A163192-", - "C163193-", - "T163194-", - "A163195-", - "A163196-", - "C163197-", - "T165054-", - "C165055-", - "T166655-", - "T166656-", - "T166711-", - "T168120-", - "T168214-", - "A168956-", - "A169024-", - "T169162-", - "A169581-", - "T169721A", - "A169769-", - "C169770-", - "A169771-", - "G169772-", - "A169773-", - "T169774-", - "G169775-", - "T169776-", - "A169777-", - "G169778-", - "A169779-", - "A169780-", - "G169781-", - "A169782-", - "T169783-", - "A169784-", - "T169785-", - "C169786-", - "A169787-", - "T169788-", - "G169789-", - "A169790-", - "A169791-", - "T169792-", - "G169793-", - "A169794-", - "A169795G", - "A169796T", - "A170723-", - "T170897-", - "T170898-", - "G170914-", - "T172059-", - "T172086-", - "T172087-", - "T172661-", - "G173004-", - "T173005-", - "G173006-", - "A173007-", - "C173008-", - "A173009-", - "T173010-", - "G173011-", - "A173012-", - "T173013-", - "G173014-", - "T173015-", - "C173016-", - "G173017-", - "T173018-", - "T173019-", - "A173020-", - "A173021-", - "A173022-", - "T173023-", - "T173024-", - "T173025-", - "G173026-", - "A173027-", - "C173028-", - "A173029-", - "A173030-", - "T173031-", - "C173032-", - "G173033-", - "T173034-", - "G173035-", - "T173036-", - "C173037-", - "T173038-", - "G173039-", - "T173040-", - "C173041-", - "T173042-", - "C173043-", - "A173044-", - "G173045-", - "A173046-", - "A173047-", - "T173048-", - "C173049-", - "A173050-", - "A173051-", - "A173052-", - "T173053-", - "A173054-", - "T173055-", - "A173056-", - "G173057-", - "A173058-", - "T173059-", - "C173060-", - "T173061-", - "T173062-", - "A173063-", - "T173064-", - "C173065-", - "T173066-", - "C173067-", - "G173068-", - "T173069-", - "A173070-", - "T173071-", - "C173072-", - "C173073-", - "A173074-", - "C173075-", - "A173076-", - "A173077-", - "A173078-", - "T173079-", - "A173080-", - "G173081-", - "T173082-", - "A173083-", - "A173084-", - "A173085-", - "T173086-", - "G173087-", - "A173088-", - "G173089-", - "A173090-", - "G173091-", - "A173092-", - "T173093-", - "C173094-", - "T173095-", - "A173096-", - "C173097-", - "T173098-", - "G173099-", - "G173100-", - "T173101-", - "A173102-", - "A173103-", - "A173104-", - "A173105-", - "T173106-", - "G173107-", - "G173108-", - "T173109-", - "A173110-", - "T173111-", - "G173112-", - "T173113-", - "C173114-", - "C173115-", - "C173116-", - "A173117-", - "A173118-", - "T173119-", - "A173120-", - "T173121-", - "T173122-", - "A173123-", - "A173124-", - "T173125-", - "G173126-", - "C173127-", - "A173128-", - "T173129-", - "T173130-", - "T173131-", - "A173132-", - "T173133-", - "T173134-", - "T173135-", - "C173136-", - "T173137-", - "A173138-", - "G173139-", - "T173140-", - "A173141-", - "A173142-", - "C173143-", - "G173144-", - "T173145-", - "A173146-", - "A173147-", - "A173148-", - "C173149-", - "A173150-", - "C173151-", - "A173152-", - "G173153-", - "A173154-", - "A173155-", - "T173156-", - "T173157-", - "A173158-", - "T173159-", - "A173160-", - "T173161-", - "G173162-", - "G173163-", - "A173164-", - "G173165-", - "C173166-", - "G173167-", - "G173168-", - "A173169-", - "C173170-", - "A173171-", - "T173172-", - "C173173-", - "G173174-", - "A173175-", - "C173176-", - "G173177-", - "C173178-", - "C173179-", - "T173180-", - "T173181-", - "A173182-", - "G173183-", - "A173184-", - "A173185-", - "A173186-", - "T173187-", - "A173188-", - "A173189-", - "G173190-", - "A173191-", - "G173192-", - "A173193-", - "C173194-", - "T173195-", - "T173196-", - "A173197-", - "A173198-", - "A173199-", - "C173200-", - "A173201-", - "A173202-", - "C173203-", - "G173204-", - "G173205-", - "A173206-", - "C173207-", - "A173208-", - "C173209-", - "C173210-", - "T173211-", - "G173212-", - "G173213-", - "A173214-", - "A173215-", - "T173216-", - "T173217-", - "A173218-", - "T173219-", - "T173220-", - "A173221-", - "C173222-", - "C173223-", - "A173224-", - "T173225-", - "A173226-", - "G173227-", - "A173228-", - "A173229-", - "G173230-", - "A173231-", - "T173232-", - "G173233-", - "T173234-", - "T173235-", - "A173236-", - "G173237-", - "A173238-", - "A173239-", - "A173240-", - "A173241-", - "A173242-", - "A173243-", - "T173244-", - "G173245-", - "A173246-", - "T173247-", - "G173248-", - "C173249-", - "T173250-", - "G173251-", - "G173252-", - "T173253-", - "T173254-", - "A173255-", - "T173256-", - "T173257-", - "A173258-", - "T173259-", - "A173260-", - "C173261-", - "A173262-", - "T173263-", - "G173264-", - "T173265-", - "G173266-", - "T173267-", - "T173268-", - "T173269-", - "T173270-", - "A173271-", - "G173272-", - "A173273-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "A173300-", - "T173301-", - "A173302-", - "T173303-", - "A173304-", - "T173305-", - "A173306-", - "T173307-", - "A173308-", - "T173309-", - "A173310-", - "T173311-", - "A173312-", - "T173313-", - "A173314-", - "T173315-", - "A173316-", - "T173317-", - "G173318-", - "G173319-", - "G173320-", - "C173321-", - "A173322-", - "A173323-", - "A173324-", - "A173325-", - "C173326-", - "A173327-", - "T173328-", - "A173329-", - "T173330-", - "A173331-", - "A173332-", - "C173333-", - "G173334-", - "T173335-", - "A173336-", - "A173337-", - "C173338-", - "C173339-", - "A173340-", - "G173341-", - "A173342-", - "A173343-", - "T173344-", - "T173345-", - "A173346-", - "T173347-", - "A173348-", - "A173349-", - "A173350-", - "A173351-", - "T173352-", - "T173353-", - "A173354-", - "G173355-", - "A173356-", - "G173357-", - "G173358-", - "T173359-", - "A173360-", - "C173361-", - "G173362-", - "G173363-", - "G173364-", - "A173365-", - "T173366-", - "A173367-", - "G173368-", - "A173369-", - "A173370-", - "T173371-", - "A173372-", - "A173373-", - "T173374-", - "A173375-", - "C173376-", - "C173377-", - "T173378-", - "C173379-", - "C173380-", - "T173381-", - "A173382-", - "C173383-", - "T173384-", - "A173385-", - "T173386-", - "G173387-", - "A173388-", - "A173389-", - "A173390-", - "T173391-", - "T173392-", - "A173393-", - "C173394-", - "C173395-", - "A173396-", - "G173397-", - "A173398-", - "A173399-", - "G173400-", - "G173401-", - "A173402-", - "G173403-", - "T173404-", - "A173405-", - "G173406-", - "T173407-", - "A173408-", - "A173409-", - "C173410-", - "T173411-", - "T173412-", - "C173413-", - "A173414-", - "A173415-", - "T173416-", - "A173417-", - "G173418-", - "G173419-", - "T173420-", - "A173421-", - "G173422-", - "T173423-", - "A173424-", - "A173425-", - "T173426-", - "T173427-", - "T173428-", - "G173429-", - "A173430-", - "C173431-", - "T173432-", - "A173433-", - "T173434-", - "T173435-", - "G173436-", - "C173437-", - "A173438-", - "T173439-", - "G173440-", - "T173441-", - "A173442-", - "G173443-", - "A173444-", - "G173445-", - "T173446-", - "A173447-", - "T173448-", - "C173449-", - "G173450-", - "T173451-", - "T173452-", - "G173453-", - "A173454-", - "G173455-", - "A173456-", - "C173457-", - "T173458-", - "T173459-", - "C173460-", - "C173461-", - "C173462-", - "A173463-", - "C173464-", - "A173465-", - "A173466-", - "C173467-", - "G173468-", - "G173469-", - "A173470-", - "C173471-", - "A173472-", - "C173473-", - "C173474-", - "G173475-", - "A173476-", - "C173477-", - "G173478-", - "T173479-", - "C173480-", - "T173481-", - "T173482-", - "T173483-", - "T173484-", - "G173485-", - "G173486-", - "A173487-", - "T173488-", - "A173489-", - "A173490-", - "G173491-", - "T173492-", - "A173493-", - "A173494-", - "T173495-", - "G173496-", - "G173497-", - "T173498-", - "A173499-", - "T173500-", - "A173501-", - "T173502-", - "G173503-", - "T173504-", - "A173505-", - "T173506-", - "T173507-", - "A173508-", - "C173509-", - "G173510-", - "A173511-", - "A173512-", - "G173513-", - "A173514-", - "A173515-", - "G173516-", - "A173517-", - "A173518-", - "G173519-", - "A173520-", - "C173521-", - "G173522-", - "A173523-", - "G173524-", - "G173525-", - "A173526-", - "C173527-", - "G173528-", - "G173529-", - "A173530-", - "G173531-", - "A173532-", - "C173533-", - "G173534-", - "G173535-", - "T173536-", - "A173537-", - "G173538-", - "A173539-", - "A173540-", - "T173541-", - "A173542-", - "A173543-", - "G173544-", - "T173545-", - "G173546-", - "T173547-", - "A173548-", - "G173549-", - "C173550-", - "A173551-", - "A173552-", - "A173553-", - "T173554-", - "A173555-", - "A173556-", - "A173557-", - "A173558-", - "T173559-", - "C173560-", - "T173561-", - "A173562-", - "T173563-", - "A173564-", - "T173565-", - "G173566-", - "A173567-", - "C173568-", - "C173569-", - "G173570-", - "A173571-", - "T173572-", - "A173573-", - "A173574-", - "G173575-", - "A173576-", - "G173577-", - "A173578-", - "C173579-", - "G173580-", - "T173581-", - "G173582-", - "T173583-", - "T173584-", - "A173585-", - "T173586-", - "T173587-", - "A173588-", - "C173589-", - "A173590-", - "T173591-", - "C173592-", - "C173593-", - "T173594-", - "G173595-", - "G173596-", - "T173597-", - "T173598-", - "A173599-", - "A173600-", - "A173601-", - "C173602-", - "A173603-", - "T173604-", - "T173605-", - "A173606-", - "A173607-", - "T173608-", - "C173609-", - "C173610-", - "T173611-", - "G173612-", - "T173613-", - "C173614-", - "A173615-", - "A173616-", - "G173617-", - "G173618-", - "A173619-", - "A173620-", - "G173621-", - "A173622-", - "A173623-", - "G173624-", - "A173625-", - "T173626-", - "G173627-", - "C173628-", - "T173629-", - "A173630-", - "C173631-", - "A173632-", - "A173633-", - "C173634-", - "G173635-", - "T173636-", - "T173637-", - "T173638-", - "A173639-", - "C173640-", - "G173641-", - "T173642-", - "G173643-", - "T173644-", - "A173645-", - "T173646-", - "G173647-", - "G173648-", - "C173649-", - "G173650-", - "T173651-", - "T173652-", - "T173653-", - "A173654-", - "C173655-", - "T173656-", - "A173657-", - "T173658-", - "T173659-", - "C173660-", - "C173661-", - "T173662-", - "A173663-", - "G173664-", - "C173665-", - "A173666-", - "T173667-", - "C173668-", - "A173669-", - "G173670-", - "C173671-", - "A173672-", - "A173673-", - "A173674-", - "A173675-", - "C173676-", - "A173677-", - "G173678-", - "T173679-", - "T173680-", - "A173681-", - "C173682-", - "T173683-", - "G173684-", - "T173685-", - "T173686-", - "A173687-", - "G173688-", - "T173689-", - "A173690-", - "A173691-", - "A173692-", - "C173693-", - "G173694-", - "T173695-", - "G173696-", - "A173697-", - "A173698-", - "T173699-", - "G173700-", - "T173701-", - "A173702-", - "T173703-", - "G173704-", - "T173705-", - "T173706-", - "G173707-", - "T173708-", - "T173709-", - "A173710-", - "C173711-", - "A173712-", - "T173713-", - "T173714-", - "T173715-", - "C173716-", - "C173717-", - "A173718-", - "T173719-", - "A173720-", - "T173721-", - "C173722-", - "A173723-", - "A173724-", - "T173725-", - "T173726-", - "G173727-", - "A173728-", - "G173729-", - "T173730-", - "T173731-", - "T173732-", - "A173733-", - "T173734-", - "A173735-", - "A173736-", - "G173737-", - "A173738-", - "A173739-", - "T173740-", - "T173741-", - "T173742-", - "T173743-", - "T173744-", - "T173745-", - "A173746-", - "T173747-", - "A173748-", - "C173749-", - "A173750-", - "T173751-", - "T173752-", - "A173753-", - "T173754-", - "C173755-", - "T173756-", - "T173757-", - "C173758-", - "C173759-", - "A173760-", - "A173761-", - "C173762-", - "A173763-", - "A173764-", - "A173765-", - "C173766-", - "A173767-", - "A173768-", - "T173769-", - "T173770-", - "G173771-", - "A173772-", - "C173773-", - "G173774-", - "A173775-", - "A173776-", - "C173777-", - "G173778-", - "T173779-", - "A173780-", - "T173781-", - "T173782-", - "G173783-", - "C173784-", - "T173785-", - "A173786-", - "T173787-", - "G173788-", - "A173789-", - "T173790-", - "T173791-", - "A173792-", - "A173793-", - "C173794-", - "T173795-", - "C173796-", - "C173797-", - "C173798-", - "A173799-", - "C173800-", - "A173801-", - "A173802-", - "T173803-", - "A173804-", - "C173805-", - "T173806-", - "A173807-", - "T173808-", - "A173809-", - "T173810-", - "A173811-", - "T173812-", - "A173813-", - "T173814-", - "T173815-", - "A173816-", - "T173817-", - "T173818-", - "A173819-", - "A173820-", - "T173821-", - "C173822-", - "A173823-", - "T173824-", - "T173825-", - "A173826-", - "A173827-", - "C173828-", - "T173829-", - "T173830-", - "G173831-", - "C173832-", - "A173833-", - "G173834-", - "A173835-", - "C173836-", - "T173837-", - "A173838-", - "T173839-", - "A173840-", - "C173841-", - "C173842-", - "T173843-", - "A173844-", - "G173845-", - "T173846-", - "A173847-", - "G173848-", - "T173849-", - "G173850-", - "C173851-", - "T173852-", - "A173853-", - "T173854-", - "T173855-", - "T173856-", - "T173857-", - "G173858-", - "A173859-", - "C173860-", - "A173861-", - "T173862-", - "A173863-", - "C173864-", - "T173865-", - "C173866-", - "A173867-", - "T173868-", - "G173869-", - "T173870-", - "T173871-", - "C173872-", - "T173873-", - "T173874-", - "G173875-", - "T173876-", - "G173877-", - "T173878-", - "A173879-", - "A173880-", - "T173881-", - "C173882-", - "G173883-", - "C173884-", - "A173885-", - "G173886-", - "T173887-", - "A173888-", - "T173889-", - "C173890-", - "T173891-", - "A173892-", - "T173893-", - "A173894-", - "T173895-", - "T173896-", - "A173897-", - "T173898-", - "T173899-", - "A173900-", - "A173901-", - "A173902-", - "G173903-", - "T173904-", - "A173905-", - "C173906-", - "G173907-", - "T173908-", - "A173909-", - "A173910-", - "A173911-", - "T173912-", - "C173913-", - "T173914-", - "A173915-", - "G173916-", - "C173917-", - "T173918-", - "A173919-", - "T173920-", - "A173921-", - "G173922-", - "T173923-", - "T173924-", - "T173925-", - "T173926-", - "A173927-", - "T173928-", - "T173929-", - "A173930-", - "T173931-", - "T173932-", - "T173933-", - "A173934-", - "A173935-", - "T173936-", - "T173937-", - "T173938-", - "T173939-", - "A173940-", - "G173941-", - "A173942-", - "T173943-", - "A173944-", - "A173945-", - "T173946-", - "A173947-", - "T173948-", - "A173949-", - "C173950-", - "T173951-", - "G173952-", - "T173953-", - "C173954-", - "T173955-", - "C173956-", - "C173957-", - "G173958-", - "T173959-", - "A173960-", - "T173961-", - "T173962-", - "T173963-", - "T173964-", - "T173965-", - "A173966-", - "A173967-", - "A173968-", - "A173969-", - "A173970-", - "A173971-", - "T173972-", - "T173973-", - "A173974-", - "C173975-", - "C173976-", - "A173977-", - "C173978-", - "A173979-", - "T173980-", - "C173981-", - "C173982-", - "T173983-", - "T173984-", - "T173985-", - "A173986-", - "T173987-", - "T173988-", - "A173989-", - "A173990-", - "A173991-", - "T173992-", - "C173993-", - "A173994-", - "T173995-", - "G173996-", - "A173997-", - "A173998-", - "T173999-", - "G174000-", - "G174001-", - "G174002-", - "A174003-", - "A174004-", - "T174005-", - "T174006-", - "T174007-", - "C174008-", - "T174009-", - "G174010-", - "T174011-", - "G174012-", - "T174013-", - "C174014-", - "A174015-", - "T174016-", - "C174017-", - "G174018-", - "T174019-", - "T174020-", - "A174021-", - "G174022-", - "T174023-", - "A174024-", - "T174025-", - "A174026-", - "T174027-", - "T174028-", - "G174029-", - "T174030-", - "G174031-", - "A174032-", - "A174033-", - "C174034-", - "A174035-", - "A174036-", - "C174037-", - "A174038-", - "A174039-", - "G174040-", - "A174041-", - "G174042-", - "C174043-", - "A174044-", - "G174045-", - "A174046-", - "T174047-", - "A174048-", - "T174049-", - "C174050-", - "T174051-", - "A174052-", - "T174053-", - "A174054-", - "G174055-", - "G174056-", - "A174057-", - "A174058-", - "A174059-", - "G174060-", - "G174061-", - "G174062-", - "T174063-", - "G174064-", - "G174065-", - "A174066-", - "A174067-", - "T174068-", - "G174069-", - "C174070-", - "G174071-", - "A174072-", - "T174073-", - "A174074-", - "C174075-", - "A174076-", - "T174077-", - "T174078-", - "G174079-", - "A174080-", - "T174081-", - "C174082-", - "T174083-", - "A174084-", - "T174085-", - "G174086-", - "T174087-", - "A174088-", - "G174089-", - "T174090-", - "T174091-", - "T174092-", - "T174093-", - "A174094-", - "A174095-", - "A174096-", - "A174097-", - "C174098-", - "A174099-", - "T174100-", - "A174101-", - "C174102-", - "G174103-", - "C174104-", - "G174105-", - "A174106-", - "A174107-", - "C174108-", - "T174109-", - "T174110-", - "T174111-", - "G174112-", - "A174113-", - "A174114-", - "G174115-", - "A174116-", - "A174117-", - "T174118-", - "T174119-", - "T174120-", - "A174121-", - "T174122-", - "A174123-", - "T174124-", - "A174125-", - "A174126-", - "A174127-", - "T174128-", - "C174129-", - "A174130-", - "T174131-", - "C174132-", - "T174133-", - "C174134-", - "A174135-", - "C174136-", - "G174137-", - "A174138-", - "G174139-", - "A174140-", - "T174141-", - "A174142-", - "T174143-", - "T174144-", - "G174145-", - "C174146-", - "T174147-", - "C174148-", - "T174149-", - "C174150-", - "T174151-", - "G174152-", - "T174153-", - "C174154-", - "A174155-", - "T174156-", - "A174157-", - "T174158-", - "T174159-", - "C174160-", - "A174161-", - "T174162-", - "A174163-", - "C174164-", - "A174165-", - "C174166-", - "C174167-", - "T174168-", - "G174169-", - "T174170-", - "A174171-", - "T174172-", - "A174173-", - "A174174-", - "A174175-", - "C174176-", - "T174177-", - "T174178-", - "T174179-", - "C174180-", - "T174181-", - "A174182-", - "G174183-", - "A174184-", - "C174185-", - "A174186-", - "T174187-", - "C174188-", - "T174189-", - "T174190-", - "A174191-", - "C174192-", - "A174193-", - "A174194-", - "T174195-", - "G174196-", - "T174197-", - "G174198-", - "T174199-", - "T174200-", - "A174201-", - "T174202-", - "T174203-", - "T174204-", - "T174205-", - "A174206-", - "T174207-", - "G174208-", - "A174209-", - "T174210-", - "C174211-", - "A174212-", - "T174213-", - "A174214-", - "T174215-", - "T174216-", - "T174217-", - "A174218-", - "C174219-", - "A174220-", - "T174221-", - "A174222-", - "T174223-", - "T174224-", - "T174225-", - "A174226-", - "C174227-", - "T174228-", - "G174229-", - "G174230-", - "T174231-", - "A174232-", - "T174233-", - "A174234-", - "T174235-", - "C174236-", - "A174237-", - "A174238-", - "A174239-", - "G174240-", - "A174241-", - "T174242-", - "G174243-", - "T174244-", - "T174245-", - "A174246-", - "G174247-", - "A174248-", - "T174249-", - "T174250-", - "A174251-", - "G174252-", - "T174253-", - "T174254-", - "A174255-", - "A174256-", - "T174257-", - "G174258-", - "G174259-", - "G174260-", - "A174261-", - "A174262-", - "T174263-", - "C174264-", - "G174265-", - "T174266-", - "C174267-", - "T174268-", - "A174269-", - "T174270-", - "A174271-", - "A174272-", - "T174273-", - "A174274-", - "A174275-", - "T174276-", - "G174277-", - "A174278-", - "A174279-", - "T174280-", - "A174281-", - "T174282-", - "T174283-", - "A174284-", - "A174285-", - "A174286-", - "C174287-", - "A174288-", - "A174289-", - "T174290-", - "T174291-", - "A174292-", - "T174293-", - "A174294-", - "G174295-", - "G174296-", - "A174297-", - "G174298-", - "G174299-", - "A174300-", - "G174301-", - "T174302-", - "T174303-", - "T174304-", - "A174305-", - "T174306-", - "A174307-", - "C174308-", - "C174309-", - "T174310-", - "A174311-", - "C174312-", - "A174313-", - "A174314-", - "A174315-", - "A174316-", - "A174317-", - "C174318-", - "A174319-", - "T174320-", - "C174321-", - "A174322-", - "T174323-", - "A174324-", - "A174325-", - "A174326-", - "A174327-", - "A174328-", - "T174329-", - "G174330-", - "A174331-", - "G174332-", - "T174333-", - "C174334-", - "A174335-", - "T174336-", - "C174337-", - "G174338-", - "T174339-", - "C174340-", - "C174341-", - "G174342-", - "A174343-", - "T174344-", - "T174345-", - "T174346-", - "A174347-", - "T174348-", - "G174349-", - "T174350-", - "T174351-", - "T174352-", - "T174353-", - "A174354-", - "A174355-", - "A174356-", - "T174357-", - "A174358-", - "T174359-", - "A174360-", - "C174361-", - "T174362-", - "A174363-", - "A174364-", - "C174365-", - "A174366-", - "T174367-", - "T174368-", - "A174369-", - "C174370-", - "T174371-", - "A174372-", - "C174373-", - "C174374-", - "T174375-", - "T174376-", - "C174377-", - "A174378-", - "G174379-", - "A174380-", - "A174381-", - "A174382-", - "T174383-", - "T174384-", - "A174385-", - "T174386-", - "A174387-", - "T174388-", - "A174389-", - "C174390-", - "G174391-", - "A174392-", - "A174393-", - "A174394-", - "T174395-", - "A174396-", - "T174397-", - "T174398-", - "A174399-", - "T174400-", - "A174401-", - "C174402-", - "A174403-", - "T174404-", - "G174405-", - "C174406-", - "T174407-", - "G174408-", - "A174409-", - "C174410-", - "A174411-", - "A174412-", - "T174413-", - "T174414-", - "A174415-", - "A174416-", - "C174417-", - "G174418-", - "A174419-", - "T174420-", - "C174421-", - "T174422-", - "T174423-", - "T174424-", - "A174425-", - "T174426-", - "A174427-", - "A174428-", - "T174429-", - "A174430-", - "T174431-", - "A174432-", - "T174433-", - "A174434-", - "G174435-", - "T174436-", - "A174437-", - "T174438-", - "C174439-", - "C174440-", - "A174441-", - "C174442-", - "C174443-", - "T174444-", - "A174445-", - "C174446-", - "C174447-", - "A174448-", - "A174449-", - "A174450-", - "G174451-", - "T174452-", - "A174453-", - "T174454-", - "A174455-", - "A174456-", - "T174457-", - "T174458-", - "G174459-", - "T174460-", - "A174461-", - "T174462-", - "T174463-", - "T174464-", - "T174465-", - "T174466-", - "C174467-", - "T174468-", - "C174469-", - "A174470-", - "T174471-", - "G174472-", - "T174473-", - "G174474-", - "A174475-", - "T174476-", - "G174477-", - "T174478-", - "G174479-", - "T174480-", - "G174481-", - "T174482-", - "A174483-", - "A174484-", - "A174485-", - "A174486-", - "A174487-", - "A174488-", - "C174489-", - "T174490-", - "G174491-", - "A174492-", - "T174493-", - "A174494-", - "T174495-", - "T174496-", - "A174497-", - "T174498-", - "A174499-", - "T174500-", - "A174501-", - "A174502-", - "T174503-", - "T174504-", - "A174505-", - "T174506-", - "C174507-", - "T174508-", - "T174509-", - "A174510-", - "G174511-", - "T174512-", - "A174513-", - "C174514-", - "C174515-", - "T174516-", - "A174517-", - "T174518-", - "G174519-", - "A174520-", - "T174521-", - "G174522-", - "A174523-", - "A174524-", - "G174525-", - "A174526-", - "T174527-", - "G174528-", - "A174529-", - "A174530-", - "G174531-", - "A174532-", - "T174533-", - "G174534-", - "A174535-", - "A174536-", - "G174537-", - "A174538-", - "T174539-", - "G174540-", - "A174541-", - "A174542-", - "G174543-", - "A174544-", - "T174545-", - "G174546-", - "A174547-", - "T174548-", - "G174549-", - "G174550-", - "T174551-", - "C174552-", - "C174553-", - "G174554-", - "T174555-", - "A174556-", - "T174557-", - "A174558-", - "T174559-", - "A174560-", - "T174561-", - "T174562-", - "T174563-", - "T174564-", - "G174565-", - "T174566-", - "A174567-", - "T174568-", - "C174569-", - "A174570-", - "T174571-", - "T174572-", - "A174573-", - "T174574-", - "C174575-", - "G174576-", - "T174577-", - "T174578-", - "A174579-", - "T174580-", - "T174581-", - "G174582-", - "C174583-", - "T174584-", - "A174585-", - "T174586-", - "T174587-", - "C174588-", - "C174589-", - "A174590-", - "T174591-", - "A174592-", - "G174593-", - "T174594-", - "T174595-", - "A174596-", - "C174597-", - "G174598-", - "C174599-", - "C174600-", - "A174601-", - "T174602-", - "A174603-", - "G174604-", - "A174605-", - "C174606-", - "A174607-", - "T174608-", - "C174609-", - "G174610-", - "A174611-", - "A174612-", - "A174613-", - "A174614-", - "T174615-", - "G174616-", - "A174617-", - "A174618-", - "A174619-", - "T174620-", - "C174621-", - "A174622-", - "C174623-", - "C174624-", - "G174625-", - "A174626-", - "A174627-", - "T174628-", - "T174629-", - "C174630-", - "T174631-", - "T174632-", - "C174633-", - "A174634-", - "A174635-", - "T174636-", - "A174637-", - "A174638-", - "A174639-", - "A174640-", - "T174641-", - "G174642-", - "A174643-", - "G174644-", - "A174645-", - "G174646-", - "A174647-", - "T174648-", - "A174649-", - "C174650-", - "T174651-", - "C174652-", - "T174653-", - "A174654-", - "C174655-", - "C174656-", - "A174657-", - "G174658-", - "C174659-", - "T174660-", - "A174661-", - "A174662-", - "A174663-", - "G174664-", - "A174665-", - "C174666-", - "T174667-", - "C174668-", - "T174669-", - "A174670-", - "A174671-", - "A174672-", - "T174673-", - "G174674-", - "G174675-", - "T174676-", - "T174677-", - "G174678-", - "A174679-", - "A174680-", - "T174681-", - "C174682-", - "C174683-", - "A174684-", - "G174685-", - "T174686-", - "A174687-", - "T174688-", - "G174689-", - "T174690-", - "A174691-", - "T174692-", - "G174693-", - "T174694-", - "T174695-", - "T174696-", - "G174697-", - "G174698-", - "A174699-", - "G174700-", - "G174701-", - "C174702-", - "A174703-", - "C174704-", - "A174705-", - "A174706-", - "T174707-", - "G174708-", - "A174709-", - "A174710-", - "T174711-", - "G174712-", - "A174713-", - "T174714-", - "A174715-", - "T174716-", - "G174717-", - "G174718-", - "C174719-", - "C174720-", - "G174721-", - "C174722-", - "T174723-", - "C174724-", - "T174725-", - "A174726-", - "G174727-", - "G174728-", - "A174729-", - "G174730-", - "A174731-", - "G174732-", - "C174733-", - "C174734-", - "A174735-", - "T174736-", - "T174737-", - "C174738-", - "A174739-", - "G174740-", - "T174741-", - "G174742-", - "C174743-", - "A174744-", - "A174745-", - "A174746-", - "G174747-", - "T174748-", - "G174749-", - "T174750-", - "C174751-", - "C174752-", - "T174753-", - "C174754-", - "C174755-", - "T174756-", - "A174757-", - "T174758-", - "T174759-", - "G174760-", - "A174761-", - "A174762-", - "G174763-", - "A174764-", - "C174765-", - "A174766-", - "G174767-", - "T174768-", - "C174769-", - "T174770-", - "T174771-", - "T174772-", - "T174773-", - "A174774-", - "T174775-", - "C174776-", - "G174777-", - "C174778-", - "A174779-", - "T174780-", - "A174781-", - "G174782-", - "A174783-", - "T174784-", - "A174785-", - "T174786-", - "A174787-", - "A174788-", - "A174789-", - "G174790-", - "A174791-", - "C174792-", - "T174793-", - "A174794-", - "T174795-", - "G174796-", - "T174797-", - "G174798-", - "G174799-", - "T174800-", - "T174801-", - "A174802-", - "A174803-", - "A174804-", - "T174805-", - "G174806-", - "G174807-", - "G174808-", - "A174809-", - "A174810-", - "A174811-", - "G174812-", - "G174813-", - "C174814-", - "T174815-", - "A174816-", - "G174817-", - "A174818-", - "A174819-", - "A174820-", - "A174821-", - "G174822-", - "A174823-", - "A174824-", - "T174825-", - "A174826-", - "G174827-", - "A174828-", - "C174829-", - "G174830-", - "G174831-", - "C174832-", - "G174833-", - "A174834-", - "C174835-", - "A174836-", - "G174837-", - "G174838-", - "T174839-", - "T174840-", - "T174841-", - "C174842-", - "T174843-", - "A174844-", - "A174845-", - "T174846-", - "A174847-", - "A174848-", - "A174849-", - "C174850-", - "G174851-", - "T174852-", - "G174853-", - "T174854-", - "T174855-", - "A174856-", - "A174857-", - "A174858-", - "C174859-", - "A174860-", - "T174861-", - "G174862-", - "G174863-", - "T174864-", - "G174865-", - "A174866-", - "T174867-", - "T174868-", - "T174869-", - "A174870-", - "T174871-", - "G174872-", - "G174873-", - "A174874-", - "T174875-", - "A174876-", - "G174877-", - "C174878-", - "C174879-", - "A174880-", - "A174881-", - "C174882-", - "T174883-", - "A174884-", - "T174885-", - "A174886-", - "C174887-", - "A174888-", - "T174889-", - "C174890-", - "T174891-", - "A174892-", - "A174893-", - "A174894-", - "T174895-", - "T174896-", - "C174897-", - "A174898-", - "G174899-", - "T174900-", - "A174901-", - "A174902-", - "C174903-", - "C174904-", - "G174905-", - "T174906-", - "A174907-", - "G174908-", - "G174909-", - "T174910-", - "A174911-", - "T174912-", - "T174913-", - "T174914-", - "A174915-", - "T174916-", - "G174917-", - "T174918-", - "A174919-", - "C174920-", - "C174921-", - "G174922-", - "T174923-", - "A174924-", - "A174925-", - "C174926-", - "C174927-", - "A174928-", - "C174929-", - "A174930-", - "A174931-", - "A174932-", - "G174933-", - "A174934-", - "A174935-", - "T174936-", - "G174937-", - "G174938-", - "T174939-", - "G174940-", - "A174941-", - "C174942-", - "T174943-", - "G174944-", - "T174945-", - "G174946-", - "T174947-", - "T174948-", - "C174949-", - "A174950-", - "G174951-", - "G174952-", - "G174953-", - "T174954-", - "G174955-", - "T174956-", - "A174957-", - "G174958-", - "T174959-", - "T174960-", - "A174961-", - "G174962-", - "A174963-", - "T174964-", - "C174965-", - "T174966-", - "C174967-", - "A174968-", - "T174969-", - "G174970-", - "T174971-", - "G174972-", - "T174973-", - "G174974-", - "G174975-", - "A174976-", - "A174977-", - "A174978-", - "C174979-", - "C174980-", - "T174981-", - "T174982-", - "C174983-", - "T174984-", - "T174985-", - "C174986-", - "A174987-", - "T174988-", - "G174989-", - "C174990-", - "A174991-", - "T174992-", - "T174993-", - "C174994-", - "C174995-", - "A174996-", - "A174997-", - "A174998-", - "A174999-", - "A175000-", - "C175001-", - "A175002-", - "T175003-", - "A175004-", - "T175005-", - "G175006-", - "A175007-", - "A175008-", - "C175009-", - "T175010-", - "A175011-", - "G175012-", - "G175013-", - "T175014-", - "A175015-", - "C175016-", - "T175017-", - "T175018-", - "A175019-", - "T175020-", - "G175021-", - "A175022-", - "T175023-", - "A175024-", - "A175025-", - "G175026-", - "T175027-", - "A175028-", - "T175029-", - "G175030-", - "G175031-", - "C175032-", - "A175033-", - "T175034-", - "A175035-", - "G175036-", - "A175037-", - "C175038-", - "T175039-", - "T175040-", - "A175041-", - "T175042-", - "A175043-", - "C175044-", - "T175045-", - "G175046-", - "T175047-", - "G175048-", - "G175049-", - "A175050-", - "A175051-", - "T175052-", - "T175053-", - "C175054-", - "T175055-", - "T175056-", - "T175057-", - "A175058-", - "T175059-", - "G175060-", - "C175061-", - "G175062-", - "A175063-", - "A175064-", - "C175065-", - "C175066-", - "A175067-", - "T175068-", - "T175069-", - "A175070-", - "T175071-", - "A175072-", - "A175073-", - "T175074-", - "A175075-", - "A175076-", - "T175077-", - "A175078-", - "T175079-", - "A175080-", - "A175081-", - "C175082-", - "T175083-", - "T175084-", - "G175085-", - "G175086-", - "T175087-", - "A175088-", - "T175089-", - "A175090-", - "A175091-", - "A175092-", - "G175093-", - "A175094-", - "T175095-", - "A175096-", - "A175097-", - "T175098-", - "A175099-", - "A175100-", - "G175101-", - "G175102-", - "A175103-", - "A175104-", - "A175105-", - "T175106-", - "T175107-", - "A175108-", - "A175109-", - "T175110-", - "A175111-", - "T175112-", - "C175113-", - "G175114-", - "A175115-", - "C175116-", - "G175117-", - "A175118-", - "T175119-", - "T175120-", - "T175121-", - "T175122-", - "A175123-", - "A175124-", - "G175125-", - "T175126-", - "A175127-", - "T175128-", - "T175129-", - "C175130-", - "A175131-", - "C175132-", - "A175133-", - "A175134-", - "G175135-", - "C175136-", - "G175137-", - "G175138-", - "G175139-", - "A175140-", - "A175141-", - "A175142-", - "G175143-", - "G175144-", - "A175145-", - "A175146-", - "T175147-", - "T175148-", - "A175149-", - "A175150-", - "T175151-", - "T175152-", - "A175153-", - "T175154-", - "T175155-", - "C175156-", - "A175157-", - "T175158-", - "A175159-", - "A175160-", - "T175161-", - "C175162-", - "C175163-", - "A175164-", - "G175165-", - "A175166-", - "G175167-", - "T175168-", - "T175169-", - "A175170-", - "G175171-", - "A175172-", - "A175173-", - "G175174-", - "A175175-", - "T175176-", - "A175177-", - "G175178-", - "T175179-", - "G175180-", - "G175181-", - "A175182-", - "A175183-", - "G175184-", - "A175185-", - "T175186-", - "A175187-", - "C175188-", - "G175189-", - "A175190-", - "C175191-", - "T175192-", - "G175193-", - "T175194-", - "T175195-", - "A175196-", - "C175197-", - "G175198-", - "T175199-", - "T175200-", - "C175201-", - "A175202-", - "T175203-", - "T175204-", - "A175205-", - "C175206-", - "G175207-", - "A175208-", - "C175209-", - "G175210-", - "A175211-", - "C175212-", - "G175213-", - "T175214-", - "T175215-", - "A175216-", - "G175217-", - "A175218-", - "A175219-", - "T175220-", - "C175221-", - "A175222-", - "A175223-", - "G175224-", - "A175225-", - "A175226-", - "T175227-", - "G175228-", - "A175229-", - "T175230-", - "A175231-", - "T175232-", - "C175233-", - "G175234-", - "T175235-", - "A175236-", - "G175237-", - "T175238-", - "A175239-", - "T175240-", - "C175241-", - "A175242-", - "A175243-", - "G175244-", - "A175245-", - "T175246-", - "G175247-", - "T175248-", - "A175249-", - "A175250-", - "A175251-", - "A175252-", - "T175253-", - "A175254-", - "C175255-", - "T175256-", - "T175257-", - "A175258-", - "C175259-", - "G175260-", - "G175261-", - "T175262-", - "T175263-", - "A175264-", - "T175265-", - "A175266-", - "C175267-", - "C175268-", - "G175269-", - "T175270-", - "C175271-", - "A175272-", - "C175273-", - "A175274-", - "A175275-", - "G175276-", - "A175277-", - "C175278-", - "C175279-", - "A175280-", - "C175281-", - "A175282-", - "G175283-", - "G175284-", - "T175285-", - "T175286-", - "T175287-", - "A175288-", - "A175289-", - "A175290-", - "C175291-", - "T175292-", - "A175293-", - "A175294-", - "T175295-", - "A175296-", - "C175297-", - "T175298-", - "A175299-", - "G175300-", - "A175301-", - "T175302-", - "C175303-", - "C175304-", - "G175305-", - "A175306-", - "A175307-", - "A175308-", - "A175309-", - "T175310-", - "C175311-", - "A175312-", - "A175313-", - "C175314-", - "G175315-", - "T175316-", - "A175317-", - "A175318-", - "C175319-", - "G175320-", - "A175321-", - "T175322-", - "A175323-", - "G175324-", - "G175325-", - "A175326-", - "G175327-", - "A175328-", - "A175329-", - "C175330-", - "C175331-", - "T175332-", - "G175333-", - "C175334-", - "C175335-", - "A175336-", - "A175337-", - "T175338-", - "A175339-", - "T175340-", - "A175341-", - "A175342-", - "C175343-", - "A175344-", - "T175345-", - "G175346-", - "C175347-", - "A175348-", - "G175349-", - "T175350-", - "G175351-", - "C175352-", - "T175353-", - "G175354-", - "T175355-", - "G175356-", - "T175357-", - "C175358-", - "A175359-", - "A175360-", - "C175361-", - "G175362-", - "T175363-", - "C175364-", - "A175365-", - "T175366-", - "T175367-", - "A175368-", - "T175369-", - "T175370-", - "T175371-", - "G175372-", - "T175373-", - "C175374-", - "G175375-", - "A175376-", - "C175377-", - "G175378-", - "A175379-", - "T175380-", - "G175381-", - "T175382-", - "A175383-", - "C175384-", - "T175385-", - "G175386-", - "A175387-", - "T175388-", - "T175389-", - "G175390-", - "A175391-", - "A175392-", - "T175393-", - "G175394-", - "G175395-", - "G175396-", - "A175397-", - "A175398-", - "A175399-", - "A175400-", - "T175401-", - "C175402-", - "C175403-", - "A175404-", - "T175405-", - "C175406-", - "C175407-", - "G175408-", - "G175409-", - "A175410-", - "T175411-", - "G175412-", - "G175413-", - "A175414-", - "T175415-", - "T175416-", - "A175417-", - "T175418-", - "A175419-", - "G175420-", - "G175421-", - "A175422-", - "T175423-", - "T175424-", - "A175425-", - "G175426-", - "A175427-", - "T175428-", - "T175429-", - "T175430-", - "T175431-", - "G175432-", - "G175433-", - "T175434-", - "G175435-", - "T175436-", - "A175437-", - "T175438-", - "A175439-", - "C175440-", - "T175441-", - "C175442-", - "T175443-", - "A175444-", - "T175445-", - "T175446-", - "T175447-", - "T175448-", - "A175449-", - "A175450-", - "C175451-", - "T175452-", - "A175453-", - "G175454-", - "T175455-", - "A175456-", - "G175457-", - "A175458-", - "G175459-", - "G175460-", - "C175461-", - "G175462-", - "G175463-", - "T175464-", - "A175465-", - "T175466-", - "C175467-", - "A175468-", - "C175469-", - "C175470-", - "G175471-", - "A175472-", - "G175473-", - "G175474-", - "C175475-", - "G175476-", - "A175477-", - "C175478-", - "T175479-", - "T175480-", - "T175481-", - "G175482-", - "T175483-", - "A175484-", - "T175485-", - "T175486-", - "T175487-", - "T175488-", - "G175489-", - "A175490-", - "A175491-", - "A175492-", - "A175493-", - "T175494-", - "G175495-", - "T175496-", - "T175497-", - "A175498-", - "C175499-", - "T175500-", - "G175501-", - "A175502-", - "A175503-", - "G175504-", - "A175505-", - "A175506-", - "T175507-", - "A175508-", - "T175509-", - "A175510-", - "T175511-", - "A175512-", - "G175513-", - "G175514-", - "C175515-", - "A175516-", - "A175517-", - "T175518-", - "A175519-", - "C175520-", - "A175521-", - "T175522-", - "A175523-", - "T175524-", - "A175525-", - "C175526-", - "A175527-", - "T175528-", - "G175529-", - "T175530-", - "C175531-", - "G175532-", - "T175533-", - "G175534-", - "G175535-", - "A175536-", - "C175537-", - "A175538-", - "C175539-", - "A175540-", - "A175541-", - "C175542-", - "T175543-", - "A175544-", - "T175545-", - "T175546-", - "A175547-", - "T175548-", - "T175549-", - "T175550-", - "T175551-", - "G175552-", - "A175553-", - "T175554-", - "A175555-", - "A175556-", - "A175557-", - "A175558-", - "C175559-", - "T175560-", - "C175561-", - "T175562-", - "T175563-", - "A175564-", - "C175565-", - "A175566-", - "A175567-", - "C175568-", - "T175569-", - "A175570-", - "C175571-", - "A175572-", - "G175573-", - "T175574-", - "A175575-", - "G175576-", - "T175577-", - "A175578-", - "T175579-", - "T175580-", - "G175581-", - "G175582-", - "A175583-", - "G175584-", - "T175585-", - "A175586-", - "A175587-", - "A175588-", - "T175589-", - "A175590-", - "C175591-", - "A175592-", - "C175593-", - "A175594-", - "A175595-", - "T175596-", - "G175597-", - "C175598-", - "A175599-", - "T175600-", - "T175601-", - "T175602-", - "T175603-", - "T175604-", - "A175605-", - "T175606-", - "A175607-", - "T175608-", - "A175609-", - "C175610-", - "A175611-", - "T175612-", - "T175613-", - "A175614-", - "C175615-", - "T175616-", - "G175617-", - "A175618-", - "A175619-", - "T175620-", - "T175621-", - "A175622-", - "T175623-", - "T175624-", - "A175625-", - "T175626-", - "T175627-", - "A175628-", - "T175629-", - "T175630-", - "A175631-", - "A175632-", - "T175633-", - "T175634-", - "A175635-", - "T175636-", - "A175637-", - "T175638-", - "C175639-", - "G175640-", - "T175641-", - "A175642-", - "T175643-", - "T175644-", - "T175645-", - "G175646-", - "T175647-", - "G175648-", - "C175649-", - "T175650-", - "A175651-", - "T175652-", - "A175653-", - "G175654-", - "A175655-", - "A175656-", - "T175657-", - "G175658-", - "G175659-", - "A175660-", - "T175661-", - "G175662-", - "A175663-", - "A175664-", - "G175665-", - "A175666-", - "T175667-", - "A175668-", - "C175669-", - "G175670-", - "C175671-", - "G175672-", - "A175673-", - "C175674-", - "T175675-", - "A175676-", - "T175677-", - "C175678-", - "T175679-", - "A175680-", - "G175681-", - "G175682-", - "T175683-", - "A175684-", - "T175685-", - "T175686-", - "T175687-", - "G175688-", - "T175689-", - "A175690-", - "T175691-", - "C175692-", - "T175693-", - "C175694-", - "A175695-", - "C175696-", - "C175697-", - "G175698-", - "A175699-", - "T175700-", - "A175701-", - "G175702-", - "A175703-", - "G175704-", - "A175705-", - "A175706-", - "C175707-", - "A175708-", - "T175709-", - "A175710-", - "T175711-", - "A175712-", - "A175713-", - "A175714-", - "T175715-", - "G175716-", - "T175717-", - "A175718-", - "G175719-", - "A175720-", - "C175721-", - "T175722-", - "C175723-", - "T175724-", - "A175725-", - "T175726-", - "T175727-", - "A175728-", - "A175729-", - "A175730-", - "C175731-", - "A175732-", - "G175733-", - "T175734-", - "T175735-", - "G175736-", - "T175737-", - "G175738-", - "T175739-", - "A175740-", - "A175741-", - "A175742-", - "A175743-", - "T175744-", - "A175745-", - "T175746-", - "C175747-", - "A175748-", - "G175749-", - "A175750-", - "T175751-", - "C175752-", - "C175753-", - "T175754-", - "A175755-", - "A175756-", - "T175757-", - "G175758-", - "C175759-", - "A175760-", - "T175761-", - "G175762-", - "T175763-", - "T175764-", - "A175765-", - "T175766-", - "A175767-", - "G175768-", - "A175769-", - "T175770-", - "G175771-", - "T175772-", - "G175773-", - "G175774-", - "A175775-", - "T175776-", - "G175777-", - "T175778-", - "A175779-", - "C175780-", - "G175781-", - "G175782-", - "C175783-", - "T175784-", - "T175785-", - "T175786-", - "A175787-", - "C175788-", - "A175789-", - "T175790-", - "G175791-", - "A175792-", - "G175793-", - "T175794-", - "A175795-", - "C175796-", - "T175797-", - "T175798-", - "T175799-", - "T175800-", - "A175801-", - "T175802-", - "A175803-", - "A175804-", - "T175805-", - "T175806-", - "A175807-", - "T175808-", - "A175809-", - "G175810-", - "A175811-", - "T175812-", - "C175813-", - "A175814-", - "G175815-", - "T175816-", - "C175817-", - "A175818-", - "A175819-", - "C175820-", - "G175821-", - "G175822-", - "A175823-", - "A175824-", - "A175825-", - "A175826-", - "T175827-", - "A175828-", - "C175829-", - "A175830-", - "A175831-", - "G175832-", - "T175833-", - "A175834-", - "T175835-", - "A175836-", - "G175837-", - "A175838-", - "T175839-", - "A175840-", - "C175841-", - "A175842-", - "A175843-", - "C175844-", - "G175845-", - "G175846-", - "T175847-", - "T175848-", - "A175849-", - "C175850-", - "T175851-", - "A175852-", - "T175853-", - "C175854-", - "A175855-", - "A175856-", - "T175857-", - "A175858-", - "T175859-", - "T175860-", - "A175861-", - "T175862-", - "T175863-", - "C175864-", - "A175865-", - "T175866-", - "C175867-", - "T175868-", - "A175869-", - "G175870-", - "C175871-", - "G175872-", - "A175873-", - "T175874-", - "T175875-", - "A175876-", - "T175877-", - "G175878-", - "A175879-", - "A175880-", - "A175881-", - "A175882-", - "T175883-", - "T175884-", - "A175885-", - "T175886-", - "A175887-", - "A175888-", - "T175889-", - "G175890-", - "A175891-", - "A175892-", - "T175893-", - "A175894-", - "T175895-", - "T175896-", - "A175897-", - "T175898-", - "T175899-", - "A175900-", - "T175901-", - "G175902-", - "A175903-", - "T175904-", - "G175905-", - "A175906-", - "T175907-", - "T175908-", - "A175909-", - "T175910-", - "G175911-", - "A175912-", - "T175913-", - "A175914-", - "G175915-", - "A175916-", - "A175917-", - "C175918-", - "T175919-", - "G175920-", - "G175921-", - "T175922-", - "A175923-", - "T175924-", - "G175925-", - "A175926-", - "A175927-", - "C175928-", - "A175929-", - "G175930-", - "T175931-", - "G175932-", - "A175933-", - "G175934-", - "A175935-", - "G175936-", - "T175937-", - "G175938-", - "A175939-", - "T175940-", - "A175941-", - "A175942-", - "T175943-", - "A175944-", - "T175945-", - "A175946-", - "T175947-", - "C175948-", - "A175949-", - "A175950-", - "T175951-", - "C175952-", - "A175953-", - "A175954-", - "A175955-", - "A175956-", - "C175957-", - "A175958-", - "G175959-", - "A175960-", - "A175961-", - "T175962-", - "A175963-", - "C175964-", - "G175965-", - "A175966-", - "G175967-", - "A175968-", - "A175969-", - "T175970-", - "G175971-", - "A175972-", - "A175973-", - "T175974-", - "A175975-", - "T175976-", - "G175977-", - "A175978-", - "A175979-", - "T175980-", - "T175981-", - "C175982-", - "T175983-", - "A175984-", - "T175985-", - "G175986-", - "A175987-", - "T175988-", - "G175989-", - "A175990-", - "A175991-", - "A175992-", - "C175993-", - "A175994-", - "C175995-", - "A175996-", - "A175997-", - "G175998-", - "A175999-", - "T176000-", - "C176001-", - "A176002-", - "A176003-", - "A176004-", - "G176005-", - "T176006-", - "A176007-", - "C176008-", - "A176009-", - "C176010-", - "A176011-", - "A176012-", - "C176013-", - "T176014-", - "A176015-", - "G176016-", - "T176017-", - "A176018-", - "G176019-", - "A176020-", - "T176021-", - "T176022-", - "A176023-", - "C176024-", - "G176025-", - "A176026-", - "C176027-", - "A176028-", - "T176029-", - "T176030-", - "A176031-", - "A176032-", - "A176033-", - "C176034-", - "T176035-", - "C176036-", - "A176037-", - "A176038-", - "A176039-", - "A176040-", - "C176041-", - "C176042-", - "A176043-", - "A176044-", - "T176045-", - "G176046-", - "A176047-", - "G176048-", - "G176049-", - "A176050-", - "T176051-", - "G176052-", - "A176053-", - "T176054-", - "T176055-", - "T176056-", - "T176057-", - "G176058-", - "T176059-", - "T176060-", - "G176061-", - "A176062-", - "T176063-", - "G176064-", - "A176065-", - "A176066-", - "T176067-", - "T176068-", - "C176069-", - "T176070-", - "A176071-", - "T176072-", - "G176073-", - "G176074-", - "T176075-", - "T176076-", - "A176077-", - "T176078-", - "G176079-", - "A176080-", - "T176081-", - "A176082-", - "G176083-", - "A176084-", - "T176085-", - "C176086-", - "A176087-", - "G176088-", - "T176089-", - "G176090-", - "G176091-", - "G176092-", - "T176093-", - "G176094-", - "T176095-", - "C176096-", - "C176097-", - "A176098-", - "T176099-", - "G176100-", - "A176101-", - "T176102-", - "T176103-", - "A176104-", - "T176105-", - "A176106-", - "T176107-", - "A176108-", - "G176109-", - "A176110-", - "T176111-", - "G176112-", - "T176113-", - "A176114-", - "T176115-", - "C176116-", - "A176117-", - "A176118-", - "T176119-", - "T176120-", - "A176121-", - "A176122-", - "T176123-", - "A176124-", - "A176125-", - "A176126-", - "G176127-", - "T176128-", - "A176129-", - "G176130-", - "T176131-", - "A176132-", - "T176133-", - "A176134-", - "T176135-", - "G176136-", - "G176137-", - "A176138-", - "A176139-", - "G176140-", - "A176141-", - "G176142-", - "A176143-", - "G176144-", - "T176145-", - "C176146-", - "T176147-", - "C176148-", - "A176149-", - "C176150-", - "G176151-", - "T176152-", - "A176153-", - "A176154-", - "G176155-", - "A176156-", - "T176157-", - "G176158-", - "G176159-", - "T176160-", - "G176161-", - "G176162-", - "G176163-", - "A176164-", - "T176165-", - "A176166-", - "T176167-", - "A176168-", - "T176169-", - "G176170-", - "G176171-", - "C176172-", - "A176173-", - "A176174-", - "G176175-", - "A176176-", - "A176177-", - "C176178-", - "A176179-", - "T176180-", - "A176181-", - "A176182-", - "T176183-", - "G176184-", - "A176185-", - "T176186-", - "G176187-", - "G176188-", - "C176189-", - "G176190-", - "T176191-", - "A176192-", - "T176193-", - "A176194-", - "C176195-", - "A176196-", - "G176197-", - "T176198-", - "A176199-", - "T176200-", - "A176201-", - "G176202-", - "G176203-", - "A176204-", - "A176205-", - "A176206-", - "G176207-", - "G176208-", - "A176209-", - "G176210-", - "T176211-", - "G176212-", - "C176213-", - "A176214-", - "T176215-", - "A176216-", - "G176217-", - "A176218-", - "T176219-", - "A176220-", - "A176221-", - "T176222-", - "A176223-", - "T176224-", - "A176225-", - "T176226-", - "A176227-", - "C176228-", - "G176229-", - "A176230-", - "A176231-", - "G176232-", - "A176233-", - "C176234-", - "A176235-", - "G176236-", - "A176237-", - "C176238-", - "A176239-", - "T176240-", - "A176241-", - "C176242-", - "C176243-", - "G176244-", - "T176245-", - "A176246-", - "G176247-", - "A176248-", - "C176249-", - "G176250-", - "A176251-", - "A176252-", - "T176253-", - "T176254-", - "C176255-", - "T176256-", - "A176257-", - "C176258-", - "A176259-", - "A176260-", - "G176261-", - "A176262-", - "T176263-", - "A176264-", - "G176265-", - "A176266-", - "C176267-", - "A176268-", - "G176269-", - "C176270-", - "G176271-", - "T176272-", - "A176273-", - "T176274-", - "C176275-", - "A176276-", - "G176277-", - "A176278-", - "T176279-", - "G176280-", - "T176281-", - "A176282-", - "G176283-", - "A176284-", - "T176285-", - "G176286-", - "A176287-", - "C176288-", - "G176289-", - "C176290-", - "A176291-", - "G176292-", - "A176293-", - "A176294-", - "C176295-", - "A176296-", - "T176297-", - "A176298-", - "T176299-", - "A176300-", - "T176301-", - "C176302-", - "T176303-", - "C176304-", - "A176305-", - "G176306-", - "A176307-", - "T176308-", - "A176309-", - "A176310-", - "C176311-", - "T176312-", - "A176313-", - "A176314-", - "T176315-", - "G176316-", - "A176317-", - "T176318-", - "G176319-", - "T176320-", - "A176321-", - "T176322-", - "C176323-", - "T176324-", - "A176325-", - "C176326-", - "A176327-", - "C176328-", - "A176329-", - "A176330-", - "A176331-", - "C176332-", - "A176333-", - "T176334-", - "G176335-", - "G176336-", - "G176337-", - "A176338-", - "A176339-", - "A176340-", - "A176341-", - "G176342-", - "A176343-", - "A176344-", - "A176345-", - "T176346-", - "C176347-", - "A176348-", - "G176349-", - "A176350-", - "G176351-", - "T176352-", - "T176353-", - "A176354-", - "G176355-", - "A176356-", - "T176357-", - "A176358-", - "G176359-", - "A176360-", - "T176361-", - "A176362-", - "C176363-", - "A176364-", - "T176365-", - "G176366-", - "G176367-", - "A176368-", - "A176369-", - "A176370-", - "T176371-", - "G176372-", - "T176373-", - "A176374-", - "T176375-", - "C176376-", - "C176377-", - "T176378-", - "C176379-", - "G176380-", - "T176381-", - "C176382-", - "A176383-", - "T176384-", - "A176385-", - "G176386-", - "A176387-", - "T176388-", - "A176389-", - "T176390-", - "G176391-", - "G176392-", - "T176393-", - "A176394-", - "A176395-", - "G176396-", - "C176397-", - "A176398-", - "T176399-", - "T176400-", - "C176401-", - "T176402-", - "G176403-", - "T176404-", - "C176405-", - "T176406-", - "T176407-", - "T176408-", - "A176409-", - "A176410-", - "G176411-", - "G176412-", - "G176413-", - "A176414-", - "T176415-", - "T176416-", - "T176417-", - "T176418-", - "C176419-", - "T176420-", - "G176421-", - "A176422-", - "C176423-", - "A176424-", - "A176425-", - "A176426-", - "G176427-", - "T176428-", - "T176429-", - "A176430-", - "G176431-", - "A176432-", - "A176433-", - "A176434-", - "A176435-", - "A176436-", - "A176437-", - "T176438-", - "G176439-", - "A176440-", - "T176441-", - "T176442-", - "T176443-", - "A176444-", - "G176445-", - "A176446-", - "C176447-", - "A176448-", - "T176449-", - "G176450-", - "A176451-", - "A176452-", - "C176453-", - "G176454-", - "T176455-", - "G176456-", - "G176457-", - "T176458-", - "A176459-", - "A176460-", - "A176461-", - "A176462-", - "G176463-", - "A176464-", - "A176465-", - "T176466-", - "T176467-", - "A176468-", - "C176469-", - "T176470-", - "T176471-", - "T176472-", - "C176473-", - "T176474-", - "A176475-", - "A176476-", - "C176477-", - "G176478-", - "G176479-", - "T176480-", - "G176481-", - "C176482-", - "A176483-", - "T176484-", - "C176485-", - "T176486-", - "C176487-", - "T176488-", - "A176489-", - "A176490-", - "C176491-", - "A176492-", - "A176493-", - "T176494-", - "C176495-", - "A176496-", - "A176497-", - "G176498-", - "G176499-", - "A176500-", - "T176501-", - "A176502-", - "G176503-", - "C176504-", - "A176505-", - "G176506-", - "T176507-", - "A176508-", - "A176509-", - "T176510-", - "A176511-", - "A176512-", - "G176513-", - "G176514-", - "A176515-", - "T176516-", - "C176517-", - "C176518-", - "A176519-", - "A176520-", - "T176521-", - "T176522-", - "G176523-", - "C176524-", - "T176525-", - "G176526-", - "T176527-", - "T176528-", - "T176529-", - "A176530-", - "T176531-", - "T176532-", - "T176533-", - "T176534-", - "A176535-", - "G176536-", - "A176537-", - "A176538-", - "G176539-", - "A176540-", - "A176541-", - "C176542-", - "A176543-", - "A176544-", - "T176545-", - "A176546-", - "A176547-", - "T176548-", - "G176549-", - "A176550-", - "A176551-", - "T176552-", - "T176553-", - "T176554-", - "A176555-", - "G176556-", - "A176557-", - "A176558-", - "A176559-", - "T176560-", - "G176561-", - "A176562-", - "T176563-", - "T176564-", - "G176565-", - "A176566-", - "T176567-", - "A176568-", - "T176569-", - "C176570-", - "A176571-", - "T176572-", - "T176573-", - "A176574-", - "A176575-", - "C176576-", - "A176577-", - "A176578-", - "A176579-", - "C176580-", - "A176581-", - "T176582-", - "A176583-", - "C176584-", - "A176585-", - "A176586-", - "C176587-", - "T176588-", - "A176589-", - "T176590-", - "C176591-", - "T176592-", - "A176593-", - "T176594-", - "G176595-", - "A176596-", - "A176597-", - "C176598-", - "G176599-", - "C176600-", - "A176601-", - "G176602-", - "G176603-", - "T176604-", - "A176605-", - "T176606-", - "A176607-", - "T176608-", - "A176609-", - "G176610-", - "T176611-", - "A176612-", - "C176613-", - "A176614-", - "C176615-", - "T176616-", - "C176617-", - "C176618-", - "T176619-", - "A176620-", - "T176621-", - "C176622-", - "T176623-", - "A176624-", - "A176625-", - "A176626-", - "A176627-", - "A176628-", - "A176629-", - "T176630-", - "T176631-", - "A176632-", - "T176633-", - "A176634-", - "G176635-", - "A176636-", - "A176637-", - "A176638-", - "T176639-", - "T176640-", - "T176641-", - "C176642-", - "G176643-", - "A176644-", - "T176645-", - "T176646-", - "A176647-", - "T176648-", - "C176649-", - "C176650-", - "A176651-", - "T176652-", - "T176653-", - "T176654-", - "T176655-", - "T176656-", - "C176657-", - "A176658-", - "G176659-", - "A176660-", - "A176661-", - "A176662-", - "G176663-", - "T176664-", - "T176665-", - "A176666-", - "G176667-", - "T176668-", - "T176669-", - "T176670-", - "T176671-", - "G176672-", - "A176673-", - "C176674-", - "T176675-", - "A176676-", - "A176677-", - "T176678-", - "A176679-", - "A176680-", - "A176681-", - "C176682-", - "A176683-", - "T176684-", - "T176685-", - "G176686-", - "T176687-", - "C176688-", - "T176689-", - "C176690-", - "A176691-", - "A176692-", - "C176693-", - "A176694-", - "A176695-", - "T176696-", - "T176697-", - "A176698-", - "T176699-", - "T176700-", - "G176701-", - "T176702-", - "A176703-", - "A176704-", - "T176705-", - "A176706-", - "T176707-", - "A176708-", - "A176709-", - "G176710-", - "C176711-", - "G176712-", - "A176713-", - "C176714-", - "G176715-", - "G176716-", - "C176717-", - "A176718-", - "A176719-", - "A176720-", - "T176721-", - "A176722-", - "T176723-", - "G176724-", - "G176725-", - "A176726-", - "A176727-", - "C176728-", - "A176729-", - "C176730-", - "C176731-", - "A176732-", - "C176733-", - "T176734-", - "A176735-", - "C176736-", - "A176737-", - "T176738-", - "A176739-", - "T176740-", - "A176741-", - "T176742-", - "T176743-", - "A176744-", - "G176745-", - "C176746-", - "A176747-", - "T176748-", - "C176749-", - "T176750-", - "A176751-", - "A176752-", - "T176753-", - "A176754-", - "A176755-", - "A176756-", - "A176757-", - "A176758-", - "A176759-", - "A176760-", - "T176761-", - "A176762-", - "A176763-", - "T176764-", - "A176765-", - "A176766-", - "C176767-", - "T176768-", - "C176769-", - "C176770-", - "T176771-", - "A176772-", - "A176773-", - "T176774-", - "T176775-", - "A176776-", - "C176777-", - "A176778-", - "T176779-", - "G176780-", - "A176781-", - "A176782-", - "G176783-", - "T176784-", - "T176785-", - "A176786-", - "T176787-", - "T176788-", - "A176789-", - "G176790-", - "T176791-", - "G176792-", - "T176793-", - "A176794-", - "T176795-", - "A176796-", - "A176797-", - "C176798-", - "G176799-", - "G176800-", - "A176801-", - "A176802-", - "A176803-", - "T176804-", - "G176805-", - "A176806-", - "T176807-", - "A176808-", - "T176809-", - "A176810-", - "A176811-", - "A176812-", - "C176813-", - "G176814-", - "C176815-", - "A176816-", - "C176817-", - "G176818-", - "A176819-", - "G176820-", - "G176821-", - "T176822-", - "G176823-", - "A176824-", - "A176825-", - "G176826-", - "A176827-", - "T176828-", - "A176829-", - "C176830-", - "A176831-", - "C176832-", - "A176833-", - "A176834-", - "A176835-", - "T176836-", - "G176837-", - "C176838-", - "G176839-", - "A176840-", - "A176841-", - "C176842-", - "T176843-", - "C176844-", - "C176845-", - "A176846-", - "T176847-", - "T176848-", - "A176849-", - "C176850-", - "A176851-", - "C176852-", - "A176853-", - "A176854-", - "A176855-", - "T176856-", - "A176857-", - "T176858-", - "T176859-", - "T176860-", - "G176861-", - "T176862-", - "G176863-", - "T176864-", - "A176865-", - "A176866-", - "A176867-", - "T176868-", - "T176869-", - "T176870-", - "G176871-", - "T176872-", - "A176873-", - "T176874-", - "A176875-", - "T176876-", - "C176877-", - "A176878-", - "T176879-", - "A176880-", - "A176881-", - "T176882-", - "A176883-", - "T176884-", - "T176885-", - "G176886-", - "A176887-", - "A176888-", - "T176889-", - "A176890-", - "T176891-", - "G176892-", - "G176893-", - "T176894-", - "A176895-", - "T176896-", - "C176897-", - "C176898-", - "G176899-", - "A176900-", - "T176901-", - "A176902-", - "C176903-", - "T176904-", - "A176905-", - "T176906-", - "A176907-", - "A176908-", - "T176909-", - "G176910-", - "A176911-", - "A176912-", - "A176913-", - "A176914-", - "G176915-", - "A176916-", - "T176917-", - "T176918-", - "A176919-", - "T176920-", - "A176921-", - "G176922-", - "A176923-", - "C176924-", - "G176925-", - "C176926-", - "A176927-", - "T176928-", - "T176929-", - "T176930-", - "A176931-", - "T176932-", - "A176933-", - "G176934-", - "A176935-", - "G176936-", - "T176937-", - "T176938-", - "A176939-", - "G176940-", - "G176941-", - "A176942-", - "G176943-", - "C176944-", - "C176945-", - "G176946-", - "A176947-", - "T176948-", - "C176949-", - "T176950-", - "A176951-", - "A176952-", - "C176953-", - "T176954-", - "A176955-", - "T176956-", - "T176957-", - "C176958-", - "C176959-", - "A176960-", - "A176961-", - "A176962-", - "T176963-", - "G176964-", - "A176965-", - "C176966-", - "G176967-", - "A176968-", - "T176969-", - "G176970-", - "G176971-", - "A176972-", - "A176973-", - "T176974-", - "G176975-", - "A176976-", - "T176977-", - "A176978-", - "C176979-", - "C176980-", - "A176981-", - "G176982-", - "T176983-", - "A176984-", - "G176985-", - "T176986-", - "T176987-", - "T176988-", - "A176989-", - "C176990-", - "T176991-", - "G176992-", - "T176993-", - "A176994-", - "T176995-", - "A176996-", - "C176997-", - "A176998-", - "C176999-", - "T177000-", - "C177001-", - "A177002-", - "A177003-", - "A177004-", - "T177005-", - "G177006-", - "C177007-", - "C177008-", - "G177009-", - "A177010-", - "A177011-", - "T177012-", - "A177013-", - "T177014-", - "G177015-", - "G177016-", - "T177017-", - "T177018-", - "A177019-", - "T177020-", - "A177021-", - "A177022-", - "C177023-", - "A177024-", - "A177025-", - "T177026-", - "A177027-", - "T177028-", - "T177029-", - "A177030-", - "C177031-", - "T177032-", - "A177033-", - "A177034-", - "C177035-", - "A177036-", - "T177037-", - "A177038-", - "A177039-", - "A177040-", - "G177041-", - "A177042-", - "T177043-", - "A177044-", - "A177045-", - "T177046-", - "A177047-", - "C177048-", - "G177049-", - "T177050-", - "A177051-", - "A177052-", - "A177053-", - "C177054-", - "T177055-", - "A177056-", - "C177057-", - "T177058-", - "T177059-", - "A177060-", - "A177061-", - "T177062-", - "C177063-", - "T177064-", - "T177065-", - "A177066-", - "G177067-", - "T177068-", - "A177069-", - "G177070-", - "A177071-", - "C177072-", - "A177073-", - "T177074-", - "G177075-", - "C177076-", - "G177077-", - "T177078-", - "C177079-", - "A177080-", - "C177081-", - "A177082-", - "T177083-", - "A177084-", - "A177085-", - "T177086-", - "C177087-", - "T177088-", - "A177089-", - "T177090-", - "T177091-", - "T177092-", - "A177093-", - "G177094-", - "A177095-", - "G177096-", - "A177097-", - "T177098-", - "C177099-", - "G177100-", - "A177101-", - "G177102-", - "T177103-", - "C177104-", - "A177105-", - "T177106-", - "G177107-", - "C177108-", - "A177109-", - "C177110-", - "G177111-", - "A177112-", - "T177113-", - "T177114-", - "A177115-", - "T177116-", - "A177117-", - "T177118-", - "A177119-", - "A177120-", - "G177121-", - "T177122-", - "A177123-", - "A177124-", - "T177125-", - "A177126-", - "C177127-", - "A177128-", - "T177129-", - "A177130-", - "T177131-", - "A177132-", - "T177133-", - "T177134-", - "G177135-", - "A177136-", - "T177137-", - "C177138-", - "T177139-", - "T177140-", - "G177141-", - "A177142-", - "G177143-", - "T177144-", - "G177145-", - "T177146-", - "T177147-", - "T177148-", - "A177149-", - "G177150-", - "A177151-", - "T177152-", - "A177153-", - "T177154-", - "C177155-", - "A177156-", - "T177157-", - "T177158-", - "A177159-", - "G177160-", - "A177161-", - "T177162-", - "C177163-", - "A177164-", - "C177165-", - "T177166-", - "T177167-", - "G177168-", - "A177169-", - "T177170-", - "G177171-", - "G177172-", - "G177173-", - "T177174-", - "A177175-", - "C177176-", - "G177177-", - "A177178-", - "T177179-", - "A177180-", - "T177181-", - "T177182-", - "A177183-", - "A177184-", - "T177185-", - "T177186-", - "G177187-", - "T177188-", - "T177189-", - "A177190-", - "C177191-", - "T177192-", - "T177193-", - "T177194-", - "G177195-", - "A177196-", - "A177197-", - "G177198-", - "G177199-", - "A177200-", - "C177201-", - "G177202-", - "T177203-", - "A177204-", - "C177205-", - "A177206-", - "C177207-", - "C177208-", - "A177209-", - "C177210-", - "T177211-", - "T177212-", - "C177213-", - "A177214-", - "T177215-", - "T177216-", - "G177217-", - "C177218-", - "G177219-", - "C177220-", - "T177221-", - "A177222-", - "T177223-", - "A177224-", - "C177225-", - "A177226-", - "A177227-", - "T177228-", - "A177229-", - "T177230-", - "A177231-", - "A177232-", - "C177233-", - "T177234-", - "T177235-", - "C177236-", - "A177237-", - "C177238-", - "T177239-", - "C177240-", - "A177241-", - "G177242-", - "A177243-", - "T177244-", - "T177245-", - "G177246-", - "C177247-", - "T177248-", - "G177249-", - "A177250-", - "G177251-", - "T177252-", - "A177253-", - "C177254-", - "T177255-", - "T177256-", - "A177257-", - "T177258-", - "T177259-", - "A177260-", - "G177261-", - "A177262-", - "T177263-", - "C177264-", - "G177265-", - "A177266-", - "G177267-", - "G177268-", - "A177269-", - "G177270-", - "C177271-", - "T177272-", - "G177273-", - "A177274-", - "T177275-", - "A177276-", - "T177277-", - "A177278-", - "T177279-", - "C177280-", - "A177281-", - "T177282-", - "T177283-", - "A177284-", - "A177285-", - "A177286-", - "G177287-", - "A177288-", - "C177289-", - "A177290-", - "G177291-", - "A177292-", - "C177293-", - "G177294-", - "A177295-", - "T177296-", - "G177297-", - "G177298-", - "T177299-", - "A177300-", - "A177301-", - "A177302-", - "A177303-", - "C177304-", - "T177305-", - "G177306-", - "T177307-", - "A177308-", - "T177309-", - "T177310-", - "T177311-", - "G177312-", - "A177313-", - "T177314-", - "T177315-", - "T177316-", - "A177317-", - "T177318-", - "C177319-", - "G177320-", - "T177321-", - "T177322-", - "A177323-", - "T177324-", - "G177325-", - "T177326-", - "A177327-", - "G177328-", - "T177329-", - "T177330-", - "A177331-", - "C177332-", - "A177333-", - "T177334-", - "T177335-", - "C177336-", - "C177337-", - "T177338-", - "C177339-", - "T177340-", - "T177341-", - "A177342-", - "A177343-", - "A177344-", - "T177345-", - "G177346-", - "G177347-", - "A177348-", - "C177349-", - "T177350-", - "A177351-", - "G177352-", - "C177353-", - "T177354-", - "T177355-", - "T177356-", - "T177357-", - "T177358-", - "G177359-", - "A177360-", - "T177361-", - "T177362-", - "A177363-", - "G177364-", - "T177365-", - "C177366-", - "G177367-", - "T177368-", - "C177369-", - "T177370-", - "A177371-", - "C177372-", - "C177373-", - "G177374-", - "C177375-", - "C177376-", - "T177377-", - "A177378-", - "A177379-", - "A177380-", - "A177381-", - "G177382-", - "T177383-", - "G177384-", - "T177385-", - "C177386-", - "A177387-", - "T177388-", - "A177389-", - "T177390-", - "G177391-", - "C177392-", - "T177393-", - "C177394-", - "A177395-", - "C177396-", - "T177397-", - "G177398-", - "A177399-", - "C177400-", - "T177401-", - "A177402-", - "A177403-", - "C177404-", - "C177405-", - "A177406-", - "T177407-", - "A177408-", - "T177409-", - "A177410-", - "A177411-", - "T177412-", - "A177413-", - "G177414-", - "A177415-", - "T177416-", - "T177417-", - "A177418-", - "T177419-", - "G177420-", - "T177421-", - "T177422-", - "C177423-", - "T177424-", - "T177425-", - "A177426-", - "C177427-", - "G177428-", - "A177429-", - "A177430-", - "C177431-", - "A177432-", - "A177433-", - "T177434-", - "A177435-", - "G177436-", - "A177437-", - "C177438-", - "G177439-", - "T177440-", - "A177441-", - "T177442-", - "T177443-", - "A177444-", - "T177445-", - "T177446-", - "T177447-", - "G177448-", - "G177449-", - "C177450-", - "A177451-", - "G177452-", - "A177453-", - "G177454-", - "T177455-", - "C177456-", - "A177457-", - "A177458-", - "A177459-", - "T177460-", - "G177461-", - "A177462-", - "T177463-", - "T177464-", - "A177465-", - "A177466-", - "T177467-", - "A177468-", - "A177469-", - "G177470-", - "T177471-", - "A177472-", - "C177473-", - "G177474-", - "T177475-", - "A177476-", - "C177477-", - "T177478-", - "G177479-", - "T177480-", - "T177481-", - "A177482-", - "C177483-", - "T177484-", - "G177485-", - "G177486-", - "A177487-", - "C177488-", - "C177489-", - "C177490-", - "A177491-", - "T177492-", - "C177493-", - "C177494-", - "T177495-", - "T177496-", - "T177497-", - "T177498-", - "A177499-", - "T177500-", - "T177501-", - "A177502-", - "T177503-", - "A177504-", - "G177505-", - "A177506-", - "T177507-", - "T177508-", - "C177509-", - "A177510-", - "G177511-", - "A177512-", - "A177513-", - "A177514-", - "T177515-", - "G177516-", - "T177517-", - "T177518-", - "A177519-", - "T177520-", - "C177521-", - "G177522-", - "A177523-", - "A177524-", - "A177525-", - "A177526-", - "C177527-", - "A177528-", - "A177529-", - "A177530-", - "T177531-", - "T177532-", - "A177533-", - "G177534-", - "A177535-", - "C177536-", - "C177537-", - "A177538-", - "A177539-", - "T177540-", - "A177541-", - "C177542-", - "A177543-", - "A177544-", - "T177545-", - "A177546-", - "A177547-", - "T177548-", - "C177549-", - "G177550-", - "T177551-", - "T177552-", - "A177553-", - "T177554-", - "A177555-", - "A177556-", - "T177557-", - "A177558-", - "T177559-", - "G177560-", - "T177561-", - "T177562-", - "C177563-", - "G177564-", - "A177565-", - "A177566-", - "C177567-", - "A177568-", - "C177569-", - "G177570-", - "A177571-", - "T177572-", - "A177573-", - "G177574-", - "G177575-", - "G177576-", - "A177577-", - "C177578-", - "G177579-", - "T177580-", - "T177581-", - "A177582-", - "A177583-", - "T177584-", - "G177585-", - "A177586-", - "A177587-", - "A177588-", - "A177589-", - "G177590-", - "T177591-", - "A177592-", - "T177593-", - "G177594-", - "G177595-", - "C177596-", - "A177597-", - "A177598-", - "A177599-", - "G177600-", - "T177601-", - "C177602-", - "T177603-", - "T177604-", - "A177605-", - "C177606-", - "A177607-", - "T177608-", - "G177609-", - "A177610-", - "C177611-", - "C177612-", - "T177613-", - "C177614-", - "G177615-", - "A177616-", - "T177617-", - "A177618-", - "C177619-", - "A177620-", - "T177621-", - "A177622-", - "T177623-", - "A177624-", - "T177625-", - "C177626-", - "A177627-", - "A177628-", - "G177629-", - "G177630-", - "A177631-", - "T177632-", - "G177633-", - "T177634-", - "A177635-", - "C177636-", - "A177637-", - "A177638-", - "G177639-", - "T177640-", - "A177641-", - "T177642-", - "T177643-", - "A177644-", - "A177645-", - "A177646-", - "A177647-", - "T177648-", - "C177649-", - "T177650-", - "A177651-", - "C177652-", - "T177653-", - "T177654-", - "C177655-", - "C177656-", - "A177657-", - "T177658-", - "C177659-", - "A177660-", - "C177661-", - "T177662-", - "A177663-", - "A177664-", - "T177665-", - "A177666-", - "A177667-", - "T177668-", - "A177669-", - "T177670-", - "A177671-", - "A177672-", - "C177673-", - "A177674-", - "C177675-", - "T177676-", - "A177677-", - "T177678-", - "A177679-", - "C177680-", - "G177681-", - "A177682-", - "C177683-", - "A177684-", - "C177685-", - "T177686-", - "A177687-", - "T177688-", - "T177689-", - "A177690-", - "T177691-", - "A177692-", - "A177693-", - "A177694-", - "T177695-", - "A177696-", - "A177697-", - "T177698-", - "A177699-", - "A177700-", - "G177701-", - "T177702-", - "C177703-", - "A177704-", - "G177705-", - "A177706-", - "G177707-", - "T177708-", - "T177709-", - "T177710-", - "C177711-", - "C177712-", - "T177713-", - "A177714-", - "T177715-", - "A177716-", - "C177717-", - "G177718-", - "T177719-", - "C177720-", - "G177721-", - "T177722-", - "G177723-", - "T177724-", - "A177725-", - "A177726-", - "A177727-", - "C177728-", - "G177729-", - "A177730-", - "C177731-", - "A177732-", - "A177733-", - "A177734-", - "C177735-", - "A177736-", - "A177737-", - "T177738-", - "T177739-", - "A177740-", - "A177741-", - "T177742-", - "T177743-", - "A177744-", - "A177745-", - "T177746-", - "C177747-", - "T177748-", - "C177749-", - "A177750-", - "T177751-", - "A177752-", - "A177753-", - "A177754-", - "A177755-", - "T177756-", - "C177757-", - "C177758-", - "A177759-", - "A177760-", - "T177761-", - "A177762-", - "C177763-", - "A177764-", - "T177765-", - "A177766-", - "T177767-", - "C177768-", - "A177769-", - "T177770-", - "A177771-", - "A177772-", - "T177773-", - "C177774-", - "T177775-", - "T177776-", - "A177777-", - "T177778-", - "C177779-", - "G177780-", - "A177781-", - "A177782-", - "A177783-", - "A177784-", - "A177785-", - "G177786-", - "T177787-", - "T177788-", - "A177789-", - "T177790-", - "T177791-", - "A177792-", - "A177793-", - "A177794-", - "A177795-", - "A177796-", - "T177797-", - "A177798-", - "C177799-", - "A177800-", - "T177801-", - "T177802-", - "A177803-", - "G177804-", - "A177805-", - "G177806-", - "A177807-", - "A177808-", - "A177809-", - "T177810-", - "A177811-", - "T177812-", - "A177813-", - "C177814-", - "T177815-", - "T177816-", - "T177817-", - "A177818-", - "A177819-", - "C177820-", - "T177821-", - "A177822-", - "A177823-", - "T177824-", - "A177825-", - "T177826-", - "A177827-", - "G177828-", - "T177829-", - "C177830-", - "C177831-", - "T177832-", - "C177833-", - "G177834-", - "A177835-", - "G177836-", - "T177837-", - "A177838-", - "T177839-", - "A177840-", - "T177841-", - "G177842-", - "A177843-", - "T177844-", - "C177845-", - "T177846-", - "C177847-", - "A177848-", - "T177849-", - "C177850-", - "T177851-", - "C177852-", - "G177853-", - "A177854-", - "T177855-", - "C177856-", - "T177857-", - "C177858-", - "A177859-", - "A177860-", - "T177861-", - "C177862-", - "A177863-", - "T177864-", - "C177865-", - "T177866-", - "T177867-", - "A177868-", - "T177869-", - "T177870-", - "T177871-", - "G177872-", - "A177873-", - "G177874-", - "T177875-", - "C177876-", - "G177877-", - "T177878-", - "A177879-", - "T177880-", - "T177881-", - "C177882-", - "C177883-", - "T177884-", - "A177885-", - "A177886-", - "T177887-", - "G177888-", - "A177889-", - "G177890-", - "A177891-", - "T177892-", - "A177893-", - "T177894-", - "T177895-", - "A177896-", - "C177897-", - "T177898-", - "C177899-", - "G177900-", - "A177901-", - "A177902-", - "A177903-", - "T177904-", - "A177905-", - "T177906-", - "T177907-", - "A177908-", - "T177909-", - "A177910-", - "T177911-", - "A177912-", - "A177913-", - "A177914-", - "C177915-", - "T177916-", - "C177917-", - "G177918-", - "A177919-", - "C177920-", - "A177921-", - "T177922-", - "G177923-", - "T177924-", - "A177925-", - "C177926-", - "G177927-", - "A177928-", - "T177929-", - "T177930-", - "T177931-", - "A177932-", - "C177933-", - "G177934-", - "T177935-", - "A177936-", - "A177937-", - "T177938-", - "C177939-", - "T177940-", - "A177941-", - "T177942-", - "A177943-", - "T177944-", - "A177945-", - "C177946-", - "A177947-", - "A177948-", - "G177949-", - "A177950-", - "T177951-", - "A177952-", - "T177953-", - "A177954-", - "T177955-", - "G177956-", - "A177957-", - "G177958-", - "A177959-", - "G177960-", - "A177961-", - "G177962-", - "A177963-", - "A177964-", - "T177965-", - "G177966-", - "A177967-", - "T177968-", - "A177969-", - "T177970-", - "C177971-", - "A177972-", - "C177973-", - "A177974-", - "G177975-", - "A177976-", - "G177977-", - "T177978-", - "A177979-", - "T177980-", - "C177981-", - "A177982-", - "T177983-", - "A177984-", - "T177985-", - "A177986-", - "G177987-", - "A177988-", - "G177989-", - "A177990-", - "A177991-", - "T177992-", - "A177993-", - "C177994-", - "G177995-", - "A177996-", - "G177997-", - "G177998-", - "T177999-", - "C178000-", - "T178001-", - "G178002-", - "T178003-", - "T178004-", - "T178005-", - "C178006-", - "T178007-", - "A178008-", - "C178009-", - "A178010-", - "C178011-", - "A178012-", - "G178013-", - "A178014-", - "C178015-", - "A178016-", - "T178017-", - "G178018-", - "A178019-", - "A178020-", - "T178021-", - "A178022-", - "A178023-", - "T178024-", - "G178025-", - "A178026-", - "A178027-", - "T178028-", - "A178029-", - "C178030-", - "A178031-", - "C178032-", - "A178033-", - "T178034-", - "A178035-", - "C178036-", - "A178037-", - "A178038-", - "C178039-", - "G178040-", - "T178041-", - "T178042-", - "T178043-", - "T178044-", - "T178045-", - "T178046-", - "T178047-", - "T178048-", - "A178049-", - "A178050-", - "T178051-", - "C178052-", - "T178053-", - "T178054-", - "A178055-", - "G178056-", - "A178057-", - "T178058-", - "A178059-", - "T178060-", - "A178061-", - "A178062-", - "C178063-", - "A178064-", - "C178065-", - "T178066-", - "A178067-", - "A178068-", - "T178069-", - "T178070-", - "A178071-", - "C178072-", - "A178073-", - "T178074-", - "C178075-", - "A178076-", - "A178077-", - "G178078-", - "A178079-", - "T178080-", - "T178081-", - "A178082-", - "T178083-", - "A178084-", - "T178085-", - "A178086-", - "T178087-", - "T178088-", - "G178089-", - "A178090-", - "A178091-", - "A178092-", - "T178093-", - "C178094-", - "G178095-", - "T178096-", - "A178097-", - "A178098-", - "T178099-", - "T178100-", - "T178101-", - "G178102-", - "A178103-", - "G178104-", - "T178105-", - "T178106-", - "G178107-", - "T178108-", - "C178109-", - "T178110-", - "G178111-", - "A178112-", - "T178113-", - "C178114-", - "A178115-", - "T178116-", - "C178117-", - "A178118-", - "T178119-", - "G178120-", - "G178121-", - "A178122-", - "T178123-", - "A178124-", - "T178125-", - "C178126-", - "G178127-", - "A178128-", - "A178129-", - "A178130-", - "A178131-", - "T178132-", - "A178133-", - "A178134-", - "T178135-", - "A178136-", - "T178137-", - "A178138-", - "C178139-", - "G178140-", - "T178141-", - "A178142-", - "A178143-", - "C178144-", - "A178145-", - "T178146-", - "T178147-", - "A178148-", - "G178149-", - "C178150-", - "A178151-", - "A178152-", - "T178153-", - "C178154-", - "T178155-", - "T178156-", - "T178157-", - "T178158-", - "A178159-", - "G178160-", - "A178161-", - "T178162-", - "G178163-", - "A178164-", - "T178165-", - "T178166-", - "G178167-", - "A178168-", - "T178169-", - "A178170-", - "T178171-", - "A178172-", - "T178173-", - "T178174-", - "A178175-", - "T178176-", - "T178177-", - "A178178-", - "T178179-", - "G178180-", - "C178181-", - "G178182-", - "A178183-", - "T178184-", - "G178185-", - "T178186-", - "A178187-", - "A178188-", - "T178189-", - "C178190-", - "A178191-", - "T178192-", - "A178193-", - "A178194-", - "C178195-", - "T178196-", - "A178197-", - "T178198-", - "C178199-", - "G178200-", - "G178201-", - "A178202-", - "G178203-", - "A178204-", - "T178205-", - "G178206-", - "T178207-", - "A178208-", - "G178209-", - "A178210-", - "A178211-", - "A178212-", - "T178213-", - "T178214-", - "A178215-", - "A178216-", - "A178217-", - "G178218-", - "C178219-", - "G178220-", - "C178221-", - "A178222-", - "T178223-", - "A178224-", - "A178225-", - "A178226-", - "A178227-", - "C178228-", - "T178229-", - "A178230-", - "T178231-", - "T178232-", - "T178233-", - "T178234-", - "G178235-", - "G178236-", - "T178237-", - "T178238-", - "G178239-", - "C178240-", - "C178241-", - "G178242-", - "G178243-", - "A178244-", - "T178245-", - "C178246-", - "T178247-", - "A178248-", - "C178249-", - "G178250-", - "T178251-", - "A178252-", - "T178253-", - "T178254-", - "T178255-", - "T178256-", - "A178257-", - "A178258-", - "A178259-", - "A178260-", - "C178261-", - "A178262-", - "A178263-", - "T178264-", - "G178265-", - "T178266-", - "T178267-", - "C178268-", - "A178269-", - "C178270-", - "A178271-", - "A178272-", - "C178273-", - "A178274-", - "T178275-", - "C178276-", - "T178277-", - "A178278-", - "T178279-", - "G178280-", - "A178281-", - "T178282-", - "A178283-", - "G178284-", - "C178285-", - "G178286-", - "A178287-", - "G178288-", - "A178289-", - "G178290-", - "A178291-", - "T178292-", - "C178293-", - "T178294-", - "A178295-", - "G178296-", - "C178297-", - "A178298-", - "A178299-", - "C178300-", - "T178301-", - "A178302-", - "G178303-", - "A178304-", - "G178305-", - "T178306-", - "A178307-", - "A178308-", - "A178309-", - "T178310-", - "A178311-", - "T178312-", - "A178313-", - "C178314-", - "A178315-", - "G178316-", - "A178317-", - "T178318-", - "G178319-", - "T178320-", - "T178321-", - "C178322-", - "G178323-", - "A178324-", - "T178325-", - "A178326-", - "A178327-", - "A178328-", - "G178329-", - "A178330-", - "T178331-", - "G178332-", - "C178333-", - "C178334-", - "G178335-", - "T178336-", - "C178337-", - "A178338-", - "A178339-", - "A178340-", - "A178341-", - "A178342-", - "T178343-", - "A178344-", - "T178345-", - "T178346-", - "G178347-", - "T178348-", - "A178349-", - "C178350-", - "A178351-", - "G178352-", - "T178353-", - "A178354-", - "C178355-", - "T178356-", - "T178357-", - "A178358-", - "T178359-", - "A178360-", - "C178361-", - "A178362-", - "A178363-", - "T178364-", - "A178365-", - "G178366-", - "G178367-", - "T178368-", - "A178369-", - "T178370-", - "A178371-", - "T178372-", - "A178373-", - "A178374-", - "G178375-", - "T178376-", - "T178377-", - "C178378-", - "T178379-", - "A178380-", - "T178381-", - "G178382-", - "A178383-", - "A178384-", - "T178385-", - "G178386-", - "T178387-", - "G178388-", - "A178389-", - "T178390-", - "A178391-", - "G178392-", - "A178393-", - "C178394-", - "A178395-", - "T178396-", - "A178397-", - "T178398-", - "T178399-", - "A178400-", - "A178401-", - "A178402-", - "A178403-", - "T178404-", - "G178405-", - "C178406-", - "A178407-", - "C178408-", - "C178409-", - "G178410-", - "A178411-", - "C178412-", - "T178413-", - "A178414-", - "A178415-", - "G178416-", - "A178417-", - "A178418-", - "C178419-", - "G178420-", - "T178421-", - "A178422-", - "A178423-", - "A178424-", - "A178425-", - "C178426-", - "G178427-", - "A178428-", - "A178429-", - "C178430-", - "T178431-", - "A178432-", - "T178433-", - "A178434-", - "G178435-", - "A178436-", - "A178437-", - "T178438-", - "G178439-", - "T178440-", - "T178441-", - "A178442-", - "T178443-", - "A178444-", - "C178445-", - "A178446-", - "A178447-", - "T178448-", - "G178449-", - "G178450-", - "G178451-", - "T178452-", - "G178453-", - "A178454-", - "T178455-", - "G178456-", - "A178457-", - "T178458-", - "A178459-", - "A178460-", - "G178461-", - "T178462-", - "A178463-", - "G178464-", - "A178465-", - "A178466-", - "G178467-", - "A178468-", - "T178469-", - "G178470-", - "T178471-", - "T178472-", - "A178473-", - "C178474-", - "C178475-", - "C178476-", - "G178477-", - "A178478-", - "T178479-", - "A178480-", - "T178481-", - "A178482-", - "C178483-", - "C178484-", - "C178485-", - "A178486-", - "T178487-", - "A178488-", - "G178489-", - "C178490-", - "A178491-", - "T178492-", - "T178493-", - "A178494-", - "T178495-", - "C178496-", - "T178497-", - "A178498-", - "G178499-", - "T178500-", - "T178501-", - "A178502-", - "T178503-", - "G178504-", - "G178505-", - "C178506-", - "A178507-", - "T178508-", - "G178509-", - "T178510-", - "G178511-", - "T178512-", - "G178513-", - "T178514-", - "A178515-", - "T178516-", - "T178517-", - "A178518-", - "G178519-", - "A178520-", - "T178521-", - "C178522-", - "A178523-", - "A178524-", - "T178525-", - "A178526-", - "C178527-", - "A178528-", - "T178529-", - "A178530-", - "T178531-", - "A178532-", - "C178533-", - "A178534-", - "T178535-", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-", - "A178554-", - "C178555-", - "A178556-", - "C178557-", - "T178558-", - "G178559-", - "A178560-", - "T178561-", - "T178562-", - "A178563-", - "T178564-", - "A178565-", - "C178566-", - "A178567-", - "T178568-", - "C178569-", - "G178570-", - "G178571-", - "T178572-", - "A178573-", - "C178574-", - "A178575-", - "T178576-", - "A178577-", - "C178578-", - "A178579-", - "G178580-", - "T178581-", - "A178582-", - "A178583-", - "A178584-", - "T178585-", - "A178586-", - "G178587-", - "C178588-", - "A178589-", - "T178590-", - "A178591-", - "G178592-", - "A178593-", - "T178594-", - "A178595-", - "T178596-", - "G178597-", - "G178598-", - "A178599-", - "G178600-", - "G178601-", - "A178602-", - "G178603-", - "G178604-", - "A178605-", - "T178606-", - "A178607-", - "C178608-", - "A178609-", - "A178610-", - "A178611-", - "T178612-", - "A178613-", - "T178614-", - "T178615-", - "T178616-", - "C178617-", - "A178618-", - "A178619-", - "A178620-", - "T178621-", - "A178622-", - "A178623-", - "A178624-", - "G178625-", - "T178626-", - "T178627-", - "A178628-", - "T178629-", - "G178630-", - "A178631-", - "G178632-", - "A178633-", - "T178634-", - "A178635-", - "C178636-", - "G178637-", - "C178638-", - "G178639-", - "C178640-", - "T178641-", - "G178642-", - "T178643-", - "C178644-", - "A178645-", - "A178646-", - "T178647-", - "A178648-", - "A178649-", - "T178650-", - "A178651-", - "T178652-", - "A178653-", - "T178654-", - "G178655-", - "G178656-", - "A178657-", - "A178658-", - "G178659-", - "A178660-", - "C178661-", - "A178662-", - "T178663-", - "T178664-", - "A178665-", - "C178666-", - "C178667-", - "T178668-", - "A178669-", - "A178670-", - "C178671-", - "T178672-", - "T178673-", - "C178674-", - "T178675-", - "G178676-", - "A178677-", - "A178678-", - "C178679-", - "T178680-", - "G178681-", - "G178682-", - "A178683-", - "A178684-", - "C178685-", - "T178686-", - "A178687-", - "T178688-", - "A178689-", - "A178690-", - "A178691-", - "T178692-", - "C178693-", - "C178694-", - "A178695-", - "G178696-", - "G178697-", - "C178698-", - "T178699-", - "C178700-", - "T178701-", - "C178702-", - "G178703-", - "C178704-", - "A178705-", - "T178706-", - "A178707-", - "A178708-", - "A178709-", - "G178710-", - "A178711-", - "T178712-", - "G178713-", - "A178714-", - "A178715-", - "T178716-", - "A178717-", - "T178718-", - "A178719-", - "T178720-", - "A178721-", - "T178722-", - "G178723-", - "T178724-", - "T178725-", - "G178726-", - "T178727-", - "A178728-", - "T178729-", - "G178730-", - "C178731-", - "G178732-", - "A178733-", - "C178734-", - "A178735-", - "T178736-", - "C178737-", - "A178738-", - "A178739-", - "A178740-", - "G178741-", - "A178742-", - "T178743-", - "G178744-", - "A178745-", - "A178746-", - "A178747-", - "A178748-", - "A178749-", - "A178750-", - "T178751-", - "G178752-", - "T178753-", - "T178754-", - "A178755-", - "A178756-", - "G178757-", - "A178758-", - "C178759-", - "T178760-", - "T178761-", - "A178762-", - "T178763-", - "A178764-", - "T178765-", - "A178766-", - "T178767-", - "T178768-", - "T178769-", - "A178770-", - "G178771-", - "A178772-", - "T178773-", - "A178774-", - "T178775-", - "A178776-", - "A178777-", - "C178778-", - "A178779-", - "C178780-", - "G178781-", - "A178782-", - "A178783-", - "T178784-", - "A178785-", - "T178786-", - "G178787-", - "T178788-", - "A178789-", - "T178790-", - "G178791-", - "A178792-", - "C178793-", - "G178794-", - "G178795-", - "A178796-", - "T178797-", - "G178798-", - "G178799-", - "G178800-", - "A178801-", - "A178802-", - "T178803-", - "T178804-", - "G178805-", - "G178806-", - "T178807-", - "A178808-", - "A178809-", - "C178810-", - "G178811-", - "A178812-", - "T178813-", - "G178814-", - "A178815-", - "C178816-", - "A178817-", - "G178818-", - "A178819-", - "A178820-", - "A178821-", - "G178822-", - "C178823-", - "A178824-", - "G178825-", - "A178826-", - "T178827-", - "T178828-", - "G178829-", - "T178830-", - "C178831-", - "A178832-", - "G178833-", - "C178834-", - "T178835-", - "C178836-", - "T178837-", - "G178838-", - "C178839-", - "A178840-", - "T178841-", - "A178842-", - "C178843-", - "T178844-", - "A178845-", - "T178846-", - "T178847-", - "C178848-", - "T178849-", - "T178850-", - "C178851-", - "A178852-", - "T178853-", - "G178854-", - "A178855-", - "C178856-", - "A178857-", - "A178858-", - "T178859-", - "A178860-", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-", - "G178879-", - "T178880-", - "T178881-", - "A178882-", - "T178883-", - "G178884-", - "A178885-", - "A178886-", - "G178887-", - "C178888-", - "G178889-", - "T178890-", - "A178891-", - "T178892-", - "A178893-", - "T178894-", - "G178895-", - "T178896-", - "T178897-", - "A178898-", - "C178899-", - "A178900-", - "A178901-", - "G178902-", - "A178903-", - "T178904-", - "A178905-", - "C178906-", - "A178907-", - "T178908-", - "T178909-", - "T178910-", - "A178911-", - "A178912-", - "T178913-", - "G178914-", - "T178915-", - "G178916-", - "C178917-", - "T178918-", - "T178919-", - "A178920-", - "C178921-", - "G178922-", - "G178923-", - "A178924-", - "A178925-", - "C178926-", - "A178927-", - "T178928-", - "A178929-", - "T178930-", - "A178931-", - "T178932-", - "T178933-", - "T178934-", - "A178935-", - "G178936-", - "A178937-", - "A178938-", - "A178939-", - "C178940-", - "A178941-", - "T178942-", - "C178943-", - "T178944-", - "A178945-", - "C178946-", - "T178947-", - "A178948-", - "A178949-", - "C178950-", - "G178951-", - "A178952-", - "T178953-", - "T178954-", - "T178955-", - "T178956-", - "T178957-", - "T178958-", - "A178959-", - "T178960-", - "G178961-", - "C178962-", - "T178963-", - "T178964-", - "G178965-", - "T178966-", - "A178967-", - "T178968-", - "T178969-", - "A178970-", - "T178971-", - "T178972-", - "A178973-", - "A178974-", - "T178975-", - "G178976-", - "G178977-", - "T178978-", - "A178979-", - "T178980-", - "G178981-", - "T178982-", - "A178983-", - "A178984-", - "T178985-", - "A178986-", - "T178987-", - "G178988-", - "A178989-", - "T178990-", - "T178991-", - "T178992-", - "A178993-", - "A178994-", - "T178995-", - "T178996-", - "G178997-", - "A178998-", - "T178999-", - "T179000-", - "G179001-", - "T179002-", - "G179003-", - "T179004-", - "A179005-", - "C179006-", - "A179007-", - "C179008-", - "G179009-", - "A179010-", - "T179011-", - "A179012-", - "C179013-", - "C179014-", - "A179015-", - "A179016-", - "T179017-", - "T179018-", - "T179019-", - "G179020-", - "T179021-", - "C179022-", - "G179023-", - "A179024-", - "G179025-", - "T179026-", - "A179027-", - "T179028-", - "G179029-", - "A179030-", - "A179031-", - "T179032-", - "A179033-", - "C179034-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "G181049-", - "T181102-", - "A181103-", - "T181104-", - "A181105-", - "T181106-", - "T181107-", - "C181108-", - "C181109-", - "T181110-", - "A181246-", - "T183553-", - "A183554-", - "C183555-", - "T187080-", - "T187207-", - "T187770-", - "T189739-", - "A190198-", - "C190199-", - "T190395-", - "A190396T", - "A192435-", - "A192436-", - "G192437-", - "T192438-", - "C192439-", - "A192440-", - "T192441-", - "A192442-", - "A192443-", - "G192444-", - "T192445-", - "T192446-", - "A192447-", - "G192448-", - "T192449-", - "T192450-", - "A192451-", - "A192452-", - "G192453-", - "T192454-", - "C192455-", - "A192456-", - "T192457-", - "A192458-", - "A192459-", - "G192460-", - "T192461-", - "T192462-", - "A192463-", - "G192464-", - "T192465-", - "T192466-", - "A192467-", - "A192468-", - "G192469-", - "T192470-", - "C192471-", - "A192472-", - "T192473-", - "A192474-", - "A192475-", - "G192476-", - "T192477-", - "T192478-", - "A192479-", - "G192480-", - "T192481-", - "T192482-", - "A192483-", - "A192484-", - "G192485-", - "T192486-", - "C192487-", - "A192488-", - "T192489-", - "A192490-", - "A192491-", - "G192492-", - "T192493-", - "T192494-", - "A192495-", - "G192496-", - "T192497-", - "T192498-", - "A192499-", - "A192500-", - "G192501-", - "T192502-", - "C192503-", - "A192504-", - "T192505-", - "A192506-", - "A192507-", - "G192508-", - "T192509-", - "T192510-", - "A192511-", - "G192512-", - "T192513-", - "T192514-", - "A192515-", - "A192516-", - "G192517-", - "T193611C" - ], - "OPG003": [ - "Y337H" - ], - "OPG021": [ - "K230X", - "*243X" - ], - "OPG022": [ - "K121X", - "*127X" - ], - "OPG029": [ - "D153-", - "D154-" - ], - "OPG031": [ - "G258-" - ], - "OPG044": [ - "K147X", - "M148X", - "*150X" - ], - "OPG049": [ - "R314X", - "H315X", - "*319X" - ], - "OPG050": [ - "F72X", - "*76X" - ], - "OPG054": [ - "K144X", - "*440X" - ], - "OPG061": [ - "K49X", - "*232X" - ], - "OPG063": [ - "F65X", - "*480X" - ], - "OPG064": [ - "L261X", - "*738X" - ], - "OPG075": [ - "F75X", - "*109X" - ], - "OPG078": [ - "F56X", - "*74X" - ], - "OPG082": [ - "I362X", - "*383X" - ], - "OPG084": [ - "F10X", - "*677X" - ], - "OPG085": [ - "S565X", - "K585X", - "*592X" - ], - "OPG092": [ - "N351X", - "*372X" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG104": [ - "N60X", - "*134X" - ], - "OPG105": [ - "R281X", - "*1287X" - ], - "OPG109": [ - "F116X", - "K206X", - "K683X", - "*796X" - ], - "OPG114": [ - "K9X", - "I10X", - "*147X" - ], - "OPG117": [ - "F501X", - "*786X" - ], - "OPG122": [ - "F106X", - "*249X" - ], - "OPG123": [ - "N570X", - "*632X" - ], - "OPG124": [ - "N205X", - "*288X" - ], - "OPG125": [ - "G499X", - "*552X" - ], - "OPG133": [ - "G144X", - "*711X" - ], - "OPG136": [ - "N877X", - "*892X" - ], - "OPG138": [ - "N6X", - "*191X" - ], - "OPG145": [ - "L14X", - "L258X", - "*493X" - ], - "OPG149": [ - "I184X", - "K185X", - "*188X" - ], - "OPG150": [ - "*383X" - ], - "OPG151": [ - "K2X", - "K946X", - "*1165X" - ], - "OPG154": [ - "K57X", - "*111X" - ], - "OPG155": [ - "F8X", - "*147X" - ], - "OPG157": [ - "Q61X", - "H62X", - "*79X" - ], - "OPG159": [ - "N113X", - "N114-", - "N115-", - "Y116X", - "*146X" - ], - "OPG164": [ - "L227X", - "*229X" - ], - "OPG170": [ - "I218X", - "*222X" - ], - "OPG173": [ - "K34X", - "E57X", - "*75X" - ], - "OPG180": [ - "K243X", - "S554X", - "*560X" - ], - "OPG188": [ - "K436X", - "*504X" - ], - "OPG191": [ - "Y165X", - "F166X", - "*169X" - ], - "OPG193": [ - "F263X", - "*268X" - ], - "OPG197": [ - "S18T", - "T34-", - "D35-", - "V36-", - "E37-", - "D38-", - "I39-", - "M40-", - "N41-", - "E42X", - "I43L", - "*101X" - ], - "OPG198": [ - "Q229X", - "*283X" - ], - "OPG204": [ - "M1-", - "K2-", - "M3-", - "K4-", - "M5-", - "M6-", - "V7-", - "R8-", - "I9-", - "Y10-", - "F11-", - "V12-", - "S13-", - "L14-", - "S15-", - "L16-", - "L17-", - "L18-", - "F19-", - "H20-", - "S21-", - "Y22-", - "A23-", - "I24-", - "D25-", - "I26-", - "E27-", - "N28-", - "E29-", - "I30-", - "T31-", - "E32-", - "F33-", - "F34-", - "N35-", - "K36-", - "M37-", - "R38-", - "D39-", - "T40-", - "L41-", - "P42-", - "A43-", - "K44-", - "D45-", - "S46-", - "K47-", - "W48-", - "L49-", - "N50-", - "P51-", - "V52-", - "C53-", - "M54-", - "F55-", - "G56-", - "G57-", - "T58-", - "M59-", - "N60-", - "D61-", - "M62-", - "A63-", - "A64-", - "L65-", - "G66-", - "E67-", - "P68-", - "F69-", - "S70-", - "A71-", - "K72-", - "C73-", - "P74-", - "P75-", - "I76-", - "E77-", - "D78-", - "S79-", - "L80-", - "L81-", - "S82-", - "H83-", - "R84-", - "Y85-", - "K86-", - "D87-", - "Y88-", - "V89-", - "V90-", - "K91-", - "W92-", - "E93-", - "R94-", - "L95-", - "E96-", - "K97-", - "N98-", - "R99-", - "R100-", - "R101-", - "Q102-", - "V103-", - "S104-", - "N105-", - "K106-", - "R107-", - "V108-", - "K109-", - "H110-", - "G111-", - "D112-", - "L113-", - "W114-", - "I115-", - "A116-", - "N117-", - "Y118-", - "T119-", - "S120-", - "K121-", - "F122-", - "S123-", - "N124-", - "R125-", - "R126-", - "Y127-", - "L128-", - "C129-", - "T130-", - "V131-", - "T132-", - "T133-", - "K134-", - "N135-", - "G136-", - "D137-", - "C138-", - "V139-", - "Q140-", - "G141-", - "V142-", - "V143-", - "R144-", - "S145-", - "H146-", - "V147-", - "W148-", - "K149-", - "P150-", - "S151-", - "S152-", - "C153-", - "I154-", - "P155-", - "K156-", - "T157-", - "Y158-", - "E159-", - "L160-", - "G161-", - "T162-", - "Y163-", - "D164-", - "K165-", - "Y166-", - "G167-", - "I168-", - "D169-", - "L170-", - "Y171-", - "C172-", - "G173-", - "I174-", - "L175-", - "Y176-", - "A177-", - "N178-", - "H179-", - "Y180-", - "N181-", - "N182-", - "I183-", - "T184-", - "W185-", - "Y186-", - "K187-", - "D188-", - "N189-", - "K190-", - "E191-", - "I192-", - "N193-", - "I194-", - "D195-", - "D196-", - "F197-", - "K198-", - "Y199-", - "S200-", - "Q201-", - "A202-", - "G203-", - "K204-", - "E205-", - "L206-", - "I207-", - "I208-", - "H209-", - "N210-", - "P211-", - "E212-", - "L213-", - "E214-", - "D215-", - "S216-", - "G217-", - "R218-", - "Y219-", - "D220-", - "C221-", - "Y222-", - "V223-", - "H224-", - "Y225-", - "D226-", - "D227-", - "V228-", - "R229-", - "I230-", - "K231-", - "N232-", - "D233-", - "I234-", - "V235-", - "V236-", - "S237-", - "R238-", - "C239-", - "K240-", - "I241-", - "L242-", - "T243-", - "V244-", - "I245-", - "P246-", - "S247-", - "Q248-", - "D249-", - "H250-", - "R251-", - "F252-", - "K253-", - "L254-", - "I255-", - "L256-", - "D257-", - "P258-", - "K259-", - "I260-", - "N261-", - "V262-", - "T263-", - "I264-", - "G265-", - "E266-", - "P267-", - "A268-", - "N269-", - "I270-", - "T271-", - "C272-", - "S273-", - "A274-", - "V275-", - "S276-", - "T277-", - "S278-", - "L279-", - "F280-", - "V281-", - "D282-", - "D283-", - "V284-", - "L285-", - "I286-", - "E287-", - "W288-", - "E289-", - "N290-", - "P291-", - "S292-", - "G293-", - "W294-", - "I295-", - "I296-", - "G297-", - "L298-", - "D299-", - "F300-", - "G301-", - "V302-", - "Y303-", - "S304-", - "I305-", - "L306-", - "T307-", - "S308-", - "R309-", - "G310-", - "G311-", - "I312-", - "T313-", - "E314-", - "A315-", - "T316-", - "L317-", - "Y318-", - "F319-", - "E320-", - "N321-", - "V322-", - "T323-", - "E324-", - "E325-", - "Y326-", - "I327-", - "G328-", - "N329-", - "T330-", - "Y331-", - "T332-", - "C333-", - "R334-", - "G335-", - "H336-", - "N337-", - "Y338-", - "Y339-", - "F340-", - "D341-", - "K342-", - "T343-", - "L344-", - "T345-", - "T346-", - "T347-", - "V348-", - "V349-", - "L350-", - "E351-", - "*352-" - ], - "OPG205": [ - "M1-", - "D2-", - "E3-", - "D4-", - "T5-", - "R6-", - "L7-", - "S8-", - "R9-", - "Y10-", - "L11-", - "Y12-", - "L13-", - "T14-", - "D15-", - "R16-", - "E17-", - "H18-", - "I19-", - "N20-", - "V21-", - "D22-", - "S23-", - "I24-", - "K25-", - "Q26-", - "L27-", - "C28-", - "K29-", - "I30-", - "S31-", - "D32-", - "P33-", - "N34-", - "A35-", - "C36-", - "Y37-", - "R38-", - "C39-", - "G40-", - "C41-", - "T42-", - "A43-", - "L44-", - "H45-", - "E46-", - "Y47-", - "F48-", - "Y49-", - "N50-", - "Y51-", - "R52-", - "S53-", - "V54-", - "N55-", - "G56-", - "K57-", - "Y58-", - "K59-", - "Y60-", - "R61-", - "Y62-", - "N63-", - "G64-", - "Y65-", - "Y66-", - "Q67-", - "Y68-", - "Y69-", - "S70-", - "S71-", - "S72-", - "D73-", - "Y74-", - "E75-", - "N76-", - "Y77-", - "N78-", - "E79-", - "Y80-", - "Y81-", - "Y82-", - "D83-", - "D84-", - "Y85-", - "D86-", - "R87-", - "T88-", - "G89-", - "M90-", - "N91-", - "S92-", - "E93-", - "S94-", - "D95-", - "N96-", - "I97-", - "S98-", - "I99-", - "K100-", - "T101-", - "E102-", - "Y103-", - "E104-", - "N105-", - "E106-", - "Y107-", - "E108-", - "F109-", - "Y110-", - "D111-", - "E112-", - "T113-", - "Q114-", - "D115-", - "Q116-", - "S117-", - "T118-", - "Q119-", - "L120-", - "V121-", - "D122-", - "Y123-", - "D124-", - "I125-", - "K126-", - "L127-", - "K128-", - "T129-", - "N130-", - "E131-", - "D132-", - "D133-", - "F134-", - "V135-", - "D136-", - "E137-", - "F138-", - "Y139-", - "G140-", - "Y141-", - "D142-", - "R143-", - "S144-", - "V145-", - "G146-", - "V147-", - "H148-", - "D149-", - "Y150-", - "I151-", - "D152-", - "V153-", - "S154-", - "I155-", - "N156-", - "K157-", - "V158-", - "V159-", - "Y160-", - "G161-", - "R162-", - "E163-", - "S164-", - "H165-", - "V166-", - "R167-", - "W168-", - "W169-", - "D170-", - "I171-", - "W172-", - "Q173-", - "E174-", - "H175-", - "N176-", - "D177-", - "G178-", - "V179-", - "Y180-", - "S181-", - "I182-", - "G183-", - "K184-", - "E185-", - "C186-", - "I187-", - "D188-", - "N189-", - "I190-", - "Y191-", - "E192-", - "D193-", - "R194-", - "H195-", - "T196-", - "V197-", - "D198-", - "E199-", - "F200-", - "Y201-", - "K202-", - "I203-", - "D204-", - "S205-", - "V206-", - "S207-", - "D208-", - "V209-", - "D210-", - "D211-", - "A212-", - "E213-", - "H214-", - "I215-", - "S216-", - "Q217-", - "I218-", - "T219-", - "N220-", - "D221-", - "V222-", - "S223-", - "T224-", - "Q225-", - "T226-", - "W227-", - "E228-", - "K229-", - "K230-", - "S231-", - "E232-", - "L233-", - "D234-", - "R235-", - "Y236-", - "M237-", - "E238-", - "M239-", - "Y240-", - "P241-", - "R242-", - "H243-", - "R244-", - "Y245-", - "G246-", - "K247-", - "H248-", - "S249-", - "V250-", - "F251-", - "K252-", - "G253-", - "F254-", - "S255-", - "D256-", - "K257-", - "V258-", - "R259-", - "K260-", - "N261-", - "D262-", - "L263-", - "D264-", - "M265-", - "N266-", - "V267-", - "V268-", - "K269-", - "E270-", - "L271-", - "L272-", - "S273-", - "N274-", - "G275-", - "A276-", - "S277-", - "L278-", - "T279-", - "I280-", - "K281-", - "D282-", - "S283-", - "S284-", - "N285-", - "K286-", - "D287-", - "P288-", - "I289-", - "A290-", - "V291-", - "Y292-", - "F293-", - "R294-", - "R295-", - "T296-", - "I297-", - "M298-", - "N299-", - "L300-", - "E301-", - "M302-", - "I303-", - "D304-", - "I305-", - "I306-", - "N307-", - "K308-", - "H309-", - "T310-", - "T311-", - "I312-", - "Y313-", - "E314-", - "R315-", - "R316-", - "Y317-", - "I318-", - "V319-", - "H320-", - "S321-", - "Y322-", - "L323-", - "K324-", - "N325-", - "Y326-", - "R327-", - "N328-", - "F329-", - "D330-", - "Y331-", - "P332-", - "F333-", - "F334-", - "R335-", - "K336-", - "L337-", - "V338-", - "L339-", - "T340-", - "N341-", - "K342-", - "H343-", - "C344-", - "L345-", - "N346-", - "N347-", - "Y348-", - "C349-", - "N350-", - "I351-", - "S352-", - "D353-", - "G354-", - "K355-", - "Y356-", - "G357-", - "T358-", - "P359-", - "L360-", - "H361-", - "I362-", - "L363-", - "A364-", - "S365-", - "N366-", - "K367-", - "K368-", - "I369-", - "I370-", - "T371-", - "P372-", - "N373-", - "Y374-", - "M375-", - "K376-", - "L377-", - "L378-", - "V379-", - "Y380-", - "N381-", - "G382-", - "N383-", - "D384-", - "I385-", - "N386-", - "A387-", - "R388-", - "G389-", - "E390-", - "D391-", - "T392-", - "Q393-", - "M394-", - "R395-", - "T396-", - "P397-", - "L398-", - "H399-", - "K400-", - "Y401-", - "L402-", - "C403-", - "K404-", - "F405-", - "V406-", - "Y407-", - "H408-", - "N409-", - "I410-", - "E411-", - "Y412-", - "G413-", - "I414-", - "R415-", - "Y416-", - "Y417-", - "N418-", - "E419-", - "K420-", - "I421-", - "I422-", - "D423-", - "A424-", - "F425-", - "I426-", - "E427-", - "L428-", - "G429-", - "A430-", - "D431-", - "L432-", - "T433-", - "I434-", - "P435-", - "N436-", - "D437-", - "D438-", - "G439-", - "M440-", - "I441-", - "P442-", - "V443-", - "V444-", - "Y445-", - "C446-", - "I447-", - "H448-", - "S449-", - "N450-", - "A451-", - "E452-", - "Y453-", - "G454-", - "Y455-", - "N456-", - "N457-", - "I458-", - "T459-", - "N460-", - "I461-", - "K462-", - "I463-", - "I464-", - "R465-", - "K466-", - "L467-", - "L468-", - "N469-", - "L470-", - "S471-", - "R472-", - "H473-", - "A474-", - "S475-", - "H476-", - "N477-", - "L478-", - "F479-", - "R480-", - "D481-", - "R482-", - "V483-", - "M484-", - "H485-", - "D486-", - "Y487-", - "I488-", - "S489-", - "N490-", - "T491-", - "Y492-", - "I493-", - "D494-", - "L495-", - "E496-", - "C497-", - "L498-", - "D499-", - "I500-", - "I501-", - "R502-", - "S503-", - "L504-", - "D505-", - "G506-", - "Y507-", - "D508-", - "I509-", - "N510-", - "C511-", - "Y512-", - "F513-", - "E514-", - "G515-", - "R516-", - "T517-", - "P518-", - "L519-", - "H520-", - "C521-", - "A522-", - "I523-", - "Q524-", - "Y525-", - "N526-", - "F527-", - "T528-", - "Q529-", - "I530-", - "A531-", - "E532-", - "Y533-", - "L534-", - "L535-", - "D536-", - "R537-", - "G538-", - "A539-", - "D540-", - "I541-", - "S542-", - "L543-", - "K544-", - "T545-", - "D546-", - "D547-", - "G548-", - "K549-", - "T550-", - "V551-", - "F552-", - "D553-", - "L554-", - "S555-", - "L556-", - "C557-", - "S558-", - "Y559-", - "I560-", - "P561-", - "L562-", - "K563-", - "W564-", - "T565-", - "S566-", - "F567-", - "L568-", - "I569-", - "S570-", - "R571-", - "L572-", - "P573-", - "P574-", - "K575-", - "S576-", - "V577-", - "I578-", - "C579-", - "S580-", - "L581-", - "T582-", - "N583-", - "H584-", - "I585-", - "I586-", - "D587-", - "Y588-", - "V589-", - "L590-", - "T591-", - "N592-", - "N593-", - "R594-", - "R595-", - "I596-", - "I597-", - "W598-", - "Q599-", - "S600-", - "Q601-", - "M602-", - "I603-", - "N604-", - "K605-", - "Y606-", - "V607-", - "L608-", - "L609-", - "L610-", - "D611-", - "P612-", - "S613-", - "F614-", - "Y615-", - "Y616-", - "R617-", - "F618-", - "R619-", - "N620-", - "V621-", - "I622-", - "E623-", - "N624-", - "K625-", - "L626-", - "D627-", - "Q628-", - "Y629-", - "N630-", - "N631-", - "R632-", - "Y633-", - "N634-", - "M635-", - "F636-", - "E637-", - "H638-", - "D639-", - "R640-", - "D641-", - "V642-", - "N643-", - "E644-", - "K645-", - "Y646-", - "G647-", - "K648-", - "V649-", - "L650-", - "H651-", - "D652-", - "L653-", - "D654-", - "T655-", - "Y656-", - "I657-", - "K658-", - "D659-", - "V660-", - "Q661-", - "V662-", - "L663-", - "K664-", - "S665-", - "T666-", - "S667-", - "I668-", - "T669-", - "N670-", - "N671-", - "I672-", - "T673-", - "L674-", - "Y675-", - "D676-", - "T677-", - "I678-", - "I679-", - "N680-", - "N681-", - "K682-", - "S683-", - "E684-", - "F685-", - "P686-", - "I687-", - "R688-", - "R689-", - "V690-", - "N691-", - "D692-", - "K693-", - "Q694-", - "L695-", - "I696-", - "N697-", - "L698-", - "I699-", - "K700-", - "S701-", - "N702-", - "T703-", - "Y704-", - "H705-", - "N706-", - "L707-", - "I708-", - "E709-", - "K710-", - "V711-", - "I712-", - "K713-", - "N714-", - "T715-", - "L716-", - "E717-", - "K718-", - "Y719-", - "T720-", - "L721-", - "T722-", - "N723-", - "I724-", - "V725-", - "L726-", - "E727-", - "Y728-", - "M729-", - "I730-", - "S731-", - "S732-", - "R733-", - "S734-", - "Q735-", - "S736-", - "S737-", - "Y738-", - "L739-", - "S740-", - "R741-", - "I742-", - "P743-", - "N744-", - "E745-", - "I746-", - "L747-", - "L748-", - "E749-", - "I750-", - "L751-", - "Y752-", - "K753-", - "L754-", - "D755-", - "M756-", - "Y757-", - "D758-", - "L759-", - "R760-", - "N761-", - "L762-", - "Y763-", - "T764-", - "R765-", - "Y766-", - "M767-", - "R768-", - "E769-", - "N770-", - "D771-", - "I772-", - "T773-", - "E774-", - "Y775-", - "H776-", - "I777-", - "E778-", - "N779-", - "T780-", - "R781-", - "S782-", - "V783-", - "S784-", - "T785-", - "Q786-", - "T787-", - "*788-" - ], - "OPG209": [ - "G178X", - "*191X" - ], - "OPG210": [ - "L733X", - "L734X", - "*1881X" - ] - }, - "labels": { - "aa": "OPG003: Y337H; OPG021: K230X, *243X; OPG022: K121X, *127X; OPG029: D153-, D154-; OPG031: G258-; OPG044: K147X, M148X, *150X; OPG049: R314X, H315X, *319X; OPG050: F72X, *76X; OPG054: K144X, *440X; OPG061: K49X, *232X; OPG063: F65X, *480X; OPG064: L261X, *738X; OPG075: F75X, *109X; OPG078: F56X, *74X; OPG082: I362X, *383X; OPG084: F10X, *677X; OPG085: S565X, K585X, *592X; OPG092: N351X, *372X; OPG097: K266X, *345X; OPG104: N60X, *134X; OPG105: R281X, *1287X; OPG109: F116X, K206X, K683X, *796X; OPG114: K9X, I10X, *147X; OPG117: F501X, *786X; OPG122: F106X, *249X; OPG123: N570X, *632X; OPG124: N205X, *288X; OPG125: G499X, *552X; OPG133: G144X, *711X; OPG136: N877X, *892X; OPG138: N6X, *191X; OPG145: L14X, L258X, *493X; OPG149: I184X, K185X, *188X; OPG150: *383X; OPG151: K2X, K946X, *1165X; OPG154: K57X, *111X; OPG155: F8X, *147X; OPG157: Q61X, H62X, *79X; OPG159: N113X, N114-, N115-, Y116X, *146X; OPG164: L227X, *229X; OPG170: I218X, *222X; OPG173: K34X, E57X, *75X; OPG180: K243X, S554X, *560X; OPG188: K436X, *504X; OPG191: Y165X, F166X, *169X; OPG193: F263X, *268X; OPG197: S18T, T34-, D35-, V36-, E37-, D38-, I39-, M40-, N41-, E42X, I43L, *101X; OPG198: Q229X, *283X; OPG204: M1-, K2-, M3-, K4-, M5-, M6-, V7-, R8-, I9-, Y10-, F11-, V12-, S13-, L14-, S15-, L16-, L17-, L18-, F19-, H20-, S21-, Y22-, A23-, I24-, D25-, I26-, E27-, N28-, E29-, I30-, T31-, E32-, F33-, F34-, N35-, K36-, M37-, R38-, D39-, T40-, L41-, P42-, A43-, K44-, D45-, S46-, K47-, W48-, L49-, N50-, P51-, V52-, C53-, M54-, F55-, G56-, G57-, T58-, M59-, N60-, D61-, M62-, A63-, A64-, L65-, G66-, E67-, P68-, F69-, S70-, A71-, K72-, C73-, P74-, P75-, I76-, E77-, D78-, S79-, L80-, L81-, S82-, H83-, R84-, Y85-, K86-, D87-, Y88-, V89-, V90-, K91-, W92-, E93-, R94-, L95-, E96-, K97-, N98-, R99-, R100-, R101-, Q102-, V103-, S104-, N105-, K106-, R107-, V108-, K109-, H110-, G111-, D112-, L113-, W114-, I115-, A116-, N117-, Y118-, T119-, S120-, K121-, F122-, S123-, N124-, R125-, R126-, Y127-, L128-, C129-, T130-, V131-, T132-, T133-, K134-, N135-, G136-, D137-, C138-, V139-, Q140-, G141-, V142-, V143-, R144-, S145-, H146-, V147-, W148-, K149-, P150-, S151-, S152-, C153-, I154-, P155-, K156-, T157-, Y158-, E159-, L160-, G161-, T162-, Y163-, D164-, K165-, Y166-, G167-, I168-, D169-, L170-, Y171-, C172-, G173-, I174-, L175-, Y176-, A177-, N178-, H179-, Y180-, N181-, N182-, I183-, T184-, W185-, Y186-, K187-, D188-, N189-, K190-, E191-, I192-, N193-, I194-, D195-, D196-, F197-, K198-, Y199-, S200-, Q201-, A202-, G203-, K204-, E205-, L206-, I207-, I208-, H209-, N210-, P211-, E212-, L213-, E214-, D215-, S216-, G217-, R218-, Y219-, D220-, C221-, Y222-, V223-, H224-, Y225-, D226-, D227-, V228-, R229-, I230-, K231-, N232-, D233-, I234-, V235-, V236-, S237-, R238-, C239-, K240-, I241-, L242-, T243-, V244-, I245-, P246-, S247-, Q248-, D249-, H250-, R251-, F252-, K253-, L254-, I255-, L256-, D257-, P258-, K259-, I260-, N261-, V262-, T263-, I264-, G265-, E266-, P267-, A268-, N269-, I270-, T271-, C272-, S273-, A274-, V275-, S276-, T277-, S278-, L279-, F280-, V281-, D282-, D283-, V284-, L285-, I286-, E287-, W288-, E289-, N290-, P291-, S292-, G293-, W294-, I295-, I296-, G297-, L298-, D299-, F300-, G301-, V302-, Y303-, S304-, I305-, L306-, T307-, S308-, R309-, G310-, G311-, I312-, T313-, E314-, A315-, T316-, L317-, Y318-, F319-, E320-, N321-, V322-, T323-, E324-, E325-, Y326-, I327-, G328-, N329-, T330-, Y331-, T332-, C333-, R334-, G335-, H336-, N337-, Y338-, Y339-, F340-, D341-, K342-, T343-, L344-, T345-, T346-, T347-, V348-, V349-, L350-, E351-, *352-; OPG205: M1-, D2-, E3-, D4-, T5-, R6-, L7-, S8-, R9-, Y10-, L11-, Y12-, L13-, T14-, D15-, R16-, E17-, H18-, I19-, N20-, V21-, D22-, S23-, I24-, K25-, Q26-, L27-, C28-, K29-, I30-, S31-, D32-, P33-, N34-, A35-, C36-, Y37-, R38-, C39-, G40-, C41-, T42-, A43-, L44-, H45-, E46-, Y47-, F48-, Y49-, N50-, Y51-, R52-, S53-, V54-, N55-, G56-, K57-, Y58-, K59-, Y60-, R61-, Y62-, N63-, G64-, Y65-, Y66-, Q67-, Y68-, Y69-, S70-, S71-, S72-, D73-, Y74-, E75-, N76-, Y77-, N78-, E79-, Y80-, Y81-, Y82-, D83-, D84-, Y85-, D86-, R87-, T88-, G89-, M90-, N91-, S92-, E93-, S94-, D95-, N96-, I97-, S98-, I99-, K100-, T101-, E102-, Y103-, E104-, N105-, E106-, Y107-, E108-, F109-, Y110-, D111-, E112-, T113-, Q114-, D115-, Q116-, S117-, T118-, Q119-, L120-, V121-, D122-, Y123-, D124-, I125-, K126-, L127-, K128-, T129-, N130-, E131-, D132-, D133-, F134-, V135-, D136-, E137-, F138-, Y139-, G140-, Y141-, D142-, R143-, S144-, V145-, G146-, V147-, H148-, D149-, Y150-, I151-, D152-, V153-, S154-, I155-, N156-, K157-, V158-, V159-, Y160-, G161-, R162-, E163-, S164-, H165-, V166-, R167-, W168-, W169-, D170-, I171-, W172-, Q173-, E174-, H175-, N176-, D177-, G178-, V179-, Y180-, S181-, I182-, G183-, K184-, E185-, C186-, I187-, D188-, N189-, I190-, Y191-, E192-, D193-, R194-, H195-, T196-, V197-, D198-, E199-, F200-, Y201-, K202-, I203-, D204-, S205-, V206-, S207-, D208-, V209-, D210-, D211-, A212-, E213-, H214-, I215-, S216-, Q217-, I218-, T219-, N220-, D221-, V222-, S223-, T224-, Q225-, T226-, W227-, E228-, K229-, K230-, S231-, E232-, L233-, D234-, R235-, Y236-, M237-, E238-, M239-, Y240-, P241-, R242-, H243-, R244-, Y245-, G246-, K247-, H248-, S249-, V250-, F251-, K252-, G253-, F254-, S255-, D256-, K257-, V258-, R259-, K260-, N261-, D262-, L263-, D264-, M265-, N266-, V267-, V268-, K269-, E270-, L271-, L272-, S273-, N274-, G275-, A276-, S277-, L278-, T279-, I280-, K281-, D282-, S283-, S284-, N285-, K286-, D287-, P288-, I289-, A290-, V291-, Y292-, F293-, R294-, R295-, T296-, I297-, M298-, N299-, L300-, E301-, M302-, I303-, D304-, I305-, I306-, N307-, K308-, H309-, T310-, T311-, I312-, Y313-, E314-, R315-, R316-, Y317-, I318-, V319-, H320-, S321-, Y322-, L323-, K324-, N325-, Y326-, R327-, N328-, F329-, D330-, Y331-, P332-, F333-, F334-, R335-, K336-, L337-, V338-, L339-, T340-, N341-, K342-, H343-, C344-, L345-, N346-, N347-, Y348-, C349-, N350-, I351-, S352-, D353-, G354-, K355-, Y356-, G357-, T358-, P359-, L360-, H361-, I362-, L363-, A364-, S365-, N366-, K367-, K368-, I369-, I370-, T371-, P372-, N373-, Y374-, M375-, K376-, L377-, L378-, V379-, Y380-, N381-, G382-, N383-, D384-, I385-, N386-, A387-, R388-, G389-, E390-, D391-, T392-, Q393-, M394-, R395-, T396-, P397-, L398-, H399-, K400-, Y401-, L402-, C403-, K404-, F405-, V406-, Y407-, H408-, N409-, I410-, E411-, Y412-, G413-, I414-, R415-, Y416-, Y417-, N418-, E419-, K420-, I421-, I422-, D423-, A424-, F425-, I426-, E427-, L428-, G429-, A430-, D431-, L432-, T433-, I434-, P435-, N436-, D437-, D438-, G439-, M440-, I441-, P442-, V443-, V444-, Y445-, C446-, I447-, H448-, S449-, N450-, A451-, E452-, Y453-, G454-, Y455-, N456-, N457-, I458-, T459-, N460-, I461-, K462-, I463-, I464-, R465-, K466-, L467-, L468-, N469-, L470-, S471-, R472-, H473-, A474-, S475-, H476-, N477-, L478-, F479-, R480-, D481-, R482-, V483-, M484-, H485-, D486-, Y487-, I488-, S489-, N490-, T491-, Y492-, I493-, D494-, L495-, E496-, C497-, L498-, D499-, I500-, I501-, R502-, S503-, L504-, D505-, G506-, Y507-, D508-, I509-, N510-, C511-, Y512-, F513-, E514-, G515-, R516-, T517-, P518-, L519-, H520-, C521-, A522-, I523-, Q524-, Y525-, N526-, F527-, T528-, Q529-, I530-, A531-, E532-, Y533-, L534-, L535-, D536-, R537-, G538-, A539-, D540-, I541-, S542-, L543-, K544-, T545-, D546-, D547-, G548-, K549-, T550-, V551-, F552-, D553-, L554-, S555-, L556-, C557-, S558-, Y559-, I560-, P561-, L562-, K563-, W564-, T565-, S566-, F567-, L568-, I569-, S570-, R571-, L572-, P573-, P574-, K575-, S576-, V577-, I578-, C579-, S580-, L581-, T582-, N583-, H584-, I585-, I586-, D587-, Y588-, V589-, L590-, T591-, N592-, N593-, R594-, R595-, I596-, I597-, W598-, Q599-, S600-, Q601-, M602-, I603-, N604-, K605-, Y606-, V607-, L608-, L609-, L610-, D611-, P612-, S613-, F614-, Y615-, Y616-, R617-, F618-, R619-, N620-, V621-, I622-, E623-, N624-, K625-, L626-, D627-, Q628-, Y629-, N630-, N631-, R632-, Y633-, N634-, M635-, F636-, E637-, H638-, D639-, R640-, D641-, V642-, N643-, E644-, K645-, Y646-, G647-, K648-, V649-, L650-, H651-, D652-, L653-, D654-, T655-, Y656-, I657-, K658-, D659-, V660-, Q661-, V662-, L663-, K664-, S665-, T666-, S667-, I668-, T669-, N670-, N671-, I672-, T673-, L674-, Y675-, D676-, T677-, I678-, I679-, N680-, N681-, K682-, S683-, E684-, F685-, P686-, I687-, R688-, R689-, V690-, N691-, D692-, K693-, Q694-, L695-, I696-, N697-, L698-, I699-, K700-, S701-, N702-, T703-, Y704-, H705-, N706-, L707-, I708-, E709-, K710-, V711-, I712-, K713-, N714-, T715-, L716-, E717-, K718-, Y719-, T720-, L721-, T722-, N723-, I724-, V725-, L726-, E727-, Y728-, M729-, I730-, S731-, S732-, R733-, S734-, Q735-, S736-, S737-, Y738-, L739-, S740-, R741-, I742-, P743-, N744-, E745-, I746-, L747-, L748-, E749-, I750-, L751-, Y752-, K753-, L754-, D755-, M756-, Y757-, D758-, L759-, R760-, N761-, L762-, Y763-, T764-, R765-, Y766-, M767-, R768-, E769-, N770-, D771-, I772-, T773-, E774-, Y775-, H776-, I777-, E778-, N779-, T780-, R781-, S782-, V783-, S784-, T785-, Q786-, T787-, *788-; OPG209: G178X, *191X; OPG210: L733X, L734X, *1881X" - } - } - }, - { - "name": "INMI-Pt3", - "node_attrs": { - "div": 556, - "author": { - "author": "Rueca,M., Giombini,E., Gruber,C.E.M., Gramigna,G., Mazzotta,V., Carletti,F., Lapa,D., Pittalis,S., Puro,V., Fabeni,L., Butera,O., Colavita,F., Meschi,S., Matusali,G., Specchiarello,E., Vairo,F., Vaia,F., Nicastri,E., Antinori,A., Girardi,E., Maggi,F.", - "value": "Rueca,M., Giombini,E., Gruber,C.E.M., Gramigna,G., Mazzotta,V., Carletti,F., Lapa,D., Pittalis,S., Puro,V., Fabeni,L., Butera,O., Colavita,F., Meschi,S., Matusali,G., Specchiarello,E., Vairo,F., Vaia,F., Nicastri,E., Antinori,A., Girardi,E., Maggi,F." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology" - }, - "date": { - "value": "2022-05-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "INMI-Pt3" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON780016" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Italy" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "-196603A" - ] - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-2884/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Knox,N., Duggan,A., Yadav,C., Hole,D., Haidl,E., Chapel,M., Jolly,G., Domselaar,G.V., Antonation,K., Leung,A., Fernando,L., Audet,J., Hagan,M., Graham,M., Griffiths,E., Safronetz,D., Charest,H., Levade,I., Fafard,J.", - "value": "Knox,N., Duggan,A., Yadav,C., Hole,D., Haidl,E., Chapel,M., Jolly,G., Domselaar,G.V., Antonation,K., Leung,A., Fernando,L., Audet,J., Hagan,M., Graham,M., Griffiths,E., Safronetz,D., Charest,H., Levade,I., Fafard,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-05-20" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-2884/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON803432" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "C183604T" - ], - "OPG210": [ - "S750L" - ] - }, - "labels": { - "aa": "OPG210: S750L" - } - } - }, - { - "name": "WA-2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Fletcher,N., Gonzalez,G., Meredith,L., Purves,K., Carr,M., Dean,J., Keogan,B., Crowley,B., Lyons,F., O'Reilly,S., Gautier,V., Mallon,P., Gordon,S., Connell,J., De Gascun,C.F.", - "value": "Fletcher,N., Gonzalez,G., Meredith,L., Purves,K., Carr,M., Dean,J., Keogan,B., Crowley,B., Lyons,F., O'Reilly,S., Gautier,V., Mallon,P., Gordon,S., Connell,J., De Gascun,C.F." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University College Dublin, National Virus Reference Laboratory" - }, - "date": { - "value": "2022-05-30" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "WA-2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON872184" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Ireland" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T48785C", - "G49636A", - "C50017T", - "T72809C", - "G178541A", - "A178772-", - "T178773-", - "A178774-", - "T178775-", - "A178776-", - "A178777-", - "C178778-", - "A178779-", - "C178780-", - "G178781-", - "A178782-", - "A178783-", - "T178784-", - "A178785-", - "T178786-", - "G178787-", - "T178788-", - "A178789-" - ], - "OPG068": [ - "G479E" - ], - "OPG069": [ - "T11I" - ], - "OPG092": [ - "K47E" - ] - }, - "labels": { - "aa": "OPG068: G479E; OPG069: T11I; OPG092: K47E" - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-2858/2022", - "node_attrs": { - "div": 556, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-05-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-2858/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880521" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T179065-", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-" - ] - } - } - }, - { - "name": "MpxV/Spain/MD-HGUGM-6642566/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Palomino-Cabrera,R., Penas-Utrilla,D., Buenestado-Serrano,S., Perez-Lago,L., Herranz Martin,M., Veintimilla,C., Catalan,P., Munoz,P., Garcia de Viedma,D.", - "value": "Palomino-Cabrera,R., Penas-Utrilla,D., Buenestado-Serrano,S., Perez-Lago,L., Herranz Martin,M., Veintimilla,C., Catalan,P., Munoz,P., Garcia de Viedma,D." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "HGUGM, Microbial Genomics" - }, - "date": { - "value": "2022-06-21" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MpxV/Spain/MD-HGUGM-6642566/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON927243" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T179002-", - "G179003-", - "T179004-", - "A179005-", - "C179006-", - "A179007-", - "C179008-", - "G179009-", - "A179010-", - "T179011-", - "A179012-", - "C179013-", - "C179014-", - "A179015-", - "A179016-", - "T179017-", - "T179018-", - "T179019-", - "C187154T" - ] - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3611/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Chapel,M., Tyler,A., Haidl,E., Domselaar,G.V., Antonation,K., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Jolly,G., Fafard,J., Charest,H., Levade,I.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Chapel,M., Tyler,A., Haidl,E., Domselaar,G.V., Antonation,K., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Jolly,G., Fafard,J., Charest,H., Levade,I." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-06-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3611/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP013011" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C40275T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A196604-" - ], - "OPG058": [ - "D54N" - ] - }, - "labels": { - "aa": "OPG058: D54N" - } - } - }, - { - "name": "hMPXV/Austria/MUW1525179/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "date": { - "value": "2022-06-10" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1525179/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP019275" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Austria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "A107070C", - "C144546T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "G190319A", - "-196601A", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "MPXV_UK_2022_5", - "node_attrs": { - "div": 557, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-05-16" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV_UK_2022_5" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP022170" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C178569T" - ] - } - } - }, - { - "name": "MP01CHUAC", - "node_attrs": { - "div": 557, - "author": { - "author": "Aja-Macaya,P., Rumbo-Feal,S., Poza,M., Canizares,A., Vallejo,J.A., Bou,G.", - "value": "Aja-Macaya,P., Rumbo-Feal,S., Poza,M., Canizares,A., Vallejo,J.A., Bou,G." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Biomedical research institute (INIBIC), Microbiology" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MP01CHUAC" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP120937" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150330A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ] - } - } - }, - { - "name": "hMPXV/Austria/MUW1531848/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "date": { - "value": "2022-07-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1531848/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP133005" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Austria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A28532-", - "T133095-", - "T133096-", - "T133097-", - "T133098-", - "T133099-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "C188252T", - "A196604-", - "A196605-", - "G197058T", - "C197173G" - ], - "OPG044": [ - "M148X", - "*150X" - ] - }, - "labels": { - "aa": "OPG044: M148X, *150X" - } - } - }, - { - "name": "hMPXV/Austria/MUW1532243/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "date": { - "value": "2022-07-06" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1532243/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP133006" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Austria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A28532-", - "C122511T", - "T133092-", - "T133093-", - "T133094-", - "T133095-", - "T133096-", - "T133097-", - "T133098-", - "T133099-", - "G151801A", - "C153984T", - "G169886A", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "A196604-" - ], - "OPG044": [ - "M148X", - "*150X" - ], - "OPG143": [ - "E269K" - ], - "OPG178": [ - "G98E" - ], - "OPG197": [ - "E73K" - ] - }, - "labels": { - "aa": "OPG044: M148X, *150X; OPG143: E269K; OPG178: G98E; OPG197: E73K" - } - } - }, - { - "name": "hMpxV/Netherlands/NH-AUMC-0001/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Tutu van Furth AM, van der Kuip M, van Els AL, Fievez LC, van Rijckevorsel GG, van den Ouden A, Jonges M, Welkers MR, Welkers,M., Jonges,M.", - "value": "Tutu van Furth AM, van der Kuip M, van Els AL, Fievez LC, van Rijckevorsel GG, van den Ouden A, Jonges M, Welkers MR, Welkers,M., Jonges,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "hMpxV/Netherlands/NH-AUMC-0001/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP160532" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Netherlands" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A148207T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "G191845A", - "A196604-" - ], - "OPG173": [ - "E57D" - ] - }, - "labels": { - "aa": "OPG173: E57D" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI214", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Stocker,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Stocker,H., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI214" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP215205" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C73609T", - "C113740T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG093": [ - "S211L" - ], - "OPG133": [ - "D653N" - ] - }, - "labels": { - "aa": "OPG093: S211L; OPG133: D653N" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI263", - "node_attrs": { - "div": 561, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI263" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP215282" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G3698A", - "G33851A", - "C128585T", - "C132970T", - "C141143T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "C193512T" - ], - "OPG052": [ - "L49F" - ] - }, - "labels": { - "aa": "OPG052: L49F" - } - } - }, - { - "name": "Monkeypox/PT0173/2022", - "node_attrs": { - "div": 556, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-06-30" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "Monkeypox/PT0173/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP324488" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "hMpxV/Netherlands/NH-AUMC-0060/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Welkers,M., Jonges,M., de Regt,M., Ooijevaar,R., Wagemakers,A.", - "value": "Welkers,M., Jonges,M., de Regt,M., Ooijevaar,R., Wagemakers,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention" - }, - "date": { - "value": "2022-08-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "hMpxV/Netherlands/NH-AUMC-0060/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP341487" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Netherlands" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C96773T", - "C109432T", - "C114985T", - "C142356T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG117": [ - "S242L" - ], - "OPG129": [ - "D525N" - ], - "OPG133": [ - "D238N" - ], - "OPG163": [ - "S52F" - ] - }, - "labels": { - "aa": "OPG117: S242L; OPG129: D525N; OPG133: D238N; OPG163: S52F" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI329", - "node_attrs": { - "div": 557, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI329" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP373387" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C110464T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG129": [ - "G181S" - ] - }, - "labels": { - "aa": "OPG129: G181S" - } - } - }, - { - "name": "hMPXV-IHU00001", - "node_attrs": { - "div": 557, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "date": { - "value": "2022-06-13" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "hMPXV-IHU00001" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP382478" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C178006T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG205": [ - "S784F" - ] - }, - "labels": { - "aa": "OPG205: S784F" - } - } - }, - { - "name": "hMPXV-IHU00007", - "node_attrs": { - "div": 556, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "date": { - "value": "2022-07-06" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "hMPXV-IHU00007" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP382484" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133098-", - "T133099-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ] - } - } - }, - { - "name": "Monkeypox/PT0326/2022", - "node_attrs": { - "div": 556, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-06-02" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "Monkeypox/PT0326/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP414358" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "Monkeypox/PT0354/2022", - "node_attrs": { - "div": 556, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-05-23" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "Monkeypox/PT0354/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP414381" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594A", - "A11326-", - "T11327-", - "C11328-", - "T11329-", - "A11330-", - "C11331-", - "G11332-", - "A11333-", - "T11334-", - "A11335-", - "T11336-", - "T11337-", - "A11338-", - "G11339-", - "A11340-", - "T11341-", - "A11342-", - "C11343-", - "T11344-", - "T11345-", - "C11346-", - "A11347-", - "C11348-", - "T11349-", - "C11350-", - "A11351-", - "A11352-", - "T11353-", - "G11354-", - "A11355-", - "A11356-", - "T11357-", - "C11358-", - "A11359-", - "A11360-", - "T11361-", - "C11362-", - "A11363-", - "C11364-", - "A11365-", - "C11366-", - "A11367-", - "A11368-", - "T11369-", - "C11370-", - "T11371-", - "A11372-", - "A11373-", - "T11374-", - "G11375-", - "T11376-", - "A11377-", - "G11378-", - "G11379-", - "T11380-", - "T11381-", - "T11382-", - "A11383-", - "T11384-", - "G11385-", - "A11386-", - "C11387-", - "A11388-", - "T11389-", - "A11390-", - "A11391-", - "T11392-", - "A11393-", - "G11394-", - "C11395-", - "A11396-", - "T11397-", - "T11398-", - "T11399-", - "T11400-", - "C11401-", - "A11402-", - "G11403-", - "C11404-", - "A11405-", - "G11406-", - "T11407-", - "T11408-", - "C11409-", - "A11410-", - "A11411-", - "T11412-", - "G11413-", - "T11414-", - "T11415-", - "T11416-", - "C11417-", - "T11418-", - "A11419-", - "G11420-", - "A11421-", - "T11422-", - "T11423-", - "C11424-", - "G11425-", - "T11426-", - "T11427-", - "G11428-", - "A11429-", - "T11430-", - "G11431-", - "G11432-", - "C11433-", - "A11434-", - "A11435-", - "T11436-", - "G11437-", - "G11438-", - "T11439-", - "T11440-", - "A11441-", - "T11442-", - "A11443-", - "C11444-", - "A11445-", - "T11446-", - "G11447-", - "T11448-", - "A11449-", - "T11450-", - "A11451-", - "T11452-", - "C11453-", - "C11454-", - "G11455-", - "T11456-", - "T11457-", - "A11458-", - "T11459-", - "T11460-", - "T11461-", - "G11462-", - "A11463-", - "T11464-", - "C11465-", - "T11466-", - "A11467-", - "A11468-", - "T11469-", - "G11470-", - "T11471-", - "T11472-", - "G11473-", - "A11474-", - "C11475-", - "A11476-", - "T11477-", - "C11478-", - "T11479-", - "G11480-", - "A11481-", - "A11482-", - "C11483-", - "C11484-", - "G11485-", - "G11486-", - "A11487-", - "T11488-", - "T11489-", - "C11490-", - "T11491-", - "A11492-", - "G11493-", - "C11494-", - "A11495-", - "G11496-", - "T11497-", - "A11498-", - "A11499-", - "A11500-", - "G11501-", - "A11502-", - "T11503-", - "A11504-", - "C11505-", - "T11506-", - "A11507-", - "G11508-", - "A11509-", - "G11510-", - "A11511-", - "T11512-", - "T11513-", - "G11514-", - "T11515-", - "T11516-", - "T11517-", - "A11518-", - "T11519-", - "T11520-", - "A11521-", - "T11522-", - "A11523-", - "T11524-", - "C11525-", - "T11526-", - "A11527-", - "A11528-", - "C11529-", - "A11530-", - "G11531-", - "C11532-", - "C11533-", - "T11534-", - "T11535-", - "G11536-", - "T11537-", - "G11538-", - "A11539-", - "A11540-", - "G11541-", - "A11542-", - "A11543-", - "G11544-", - "T11545-", - "G11546-", - "T11547-", - "T11548-", - "T11549-", - "C11550-", - "T11551-", - "C11552-", - "C11553-", - "T11554-", - "C11555-", - "G11556-", - "T11557-", - "T11558-", - "T11559-", - "G11560-", - "T11561-", - "C11562-", - "A11563-", - "A11564-", - "T11565-", - "C11566-", - "A11567-", - "T11568-", - "G11569-", - "T11570-", - "T11571-", - "A11572-", - "A11573-", - "T11574-", - "G11575-", - "T11576-", - "C11577-", - "T11578-", - "T11579-", - "T11580-", - "A11581-", - "A11582-", - "G11583-", - "A11584-", - "T11585-", - "A11586-", - "A11587-", - "G11588-", - "G11589-", - "T11590-", - "A11591-", - "G11592-", - "A11593-", - "C11594-", - "A11595-", - "A11596-", - "A11597-", - "T11598-", - "G11599-", - "T11600-", - "T11601-", - "T11602-", - "A11603-", - "T11604-", - "A11605-", - "G11606-", - "T11607-", - "A11608-", - "C11609-", - "T11610-", - "A11611-", - "A11612-", - "G11613-", - "A11614-", - "A11615-", - "T11616-", - "T11617-", - "G11618-", - "G11619-", - "G11620-", - "C11621-", - "A11622-", - "A11623-", - "A11624-", - "C11625-", - "A11626-", - "T11627-", - "A11628-", - "A11629-", - "G11630-", - "A11631-", - "C11632-", - "A11633-", - "T11634-", - "G11635-", - "T11636-", - "C11637-", - "A11638-", - "C11639-", - "A11640-", - "A11641-", - "A11642-", - "G11643-", - "A11644-", - "C11645-", - "C11646-", - "C11647-", - "T11648-", - "T11649-", - "T11650-", - "T11651-", - "T11652-", - "G11653-", - "T11654-", - "A11655-", - "T11656-", - "G11657-", - "T11658-", - "A11659-", - "T11660-", - "A11661-", - "A11662-", - "G11663-", - "T11664-", - "G11665-", - "T11666-", - "A11667-", - "G11668-", - "A11669-", - "A11670-", - "A11671-", - "T11672-", - "T11673-", - "A11674-", - "T11675-", - "A11676-", - "A11677-", - "C11678-", - "A11679-", - "T11680-", - "C11681-", - "C11682-", - "A11683-", - "T11684-", - "A11685-", - "G11686-", - "T11687-", - "T11688-", - "G11689-", - "G11690-", - "A11691-", - "T11692-", - "T11693-", - "C11694-", - "A11695-", - "C11696-", - "A11697-", - "T11698-", - "A11699-", - "G11700-", - "G11701-", - "T11702-", - "G11703-", - "T11704-", - "C11705-", - "C11706-", - "A11707-", - "A11708-", - "T11709-", - "C11710-", - "G11711-", - "G11712-", - "G11713-", - "A11714-", - "T11715-", - "C11716-", - "T11717-", - "C11718-", - "T11719-", - "C11720-", - "C11721-", - "A11722-", - "T11723-", - "C11724-", - "A11725-", - "T11726-", - "C11727-", - "G11728-", - "A11729-", - "G11730-", - "A11731-", - "T11732-", - "G11733-", - "A11734-", - "T11735-", - "T11736-", - "G11737-", - "A11738-", - "C11739-", - "G11740-", - "G11741-", - "C11742-", - "A11743-", - "T11744-", - "C11745-", - "T11746-", - "C11747-", - "C11748-", - "C11749-", - "C11750-", - "C11751-", - "T11752-", - "T11753-", - "C11754-", - "C11755-", - "T11756-", - "T11757-", - "T11758-", - "T11759-", - "T11760-", - "T11761-", - "A11762-", - "G11763-", - "T11764-", - "A11765-", - "G11766-", - "A11767-", - "T11768-", - "A11769-", - "T11770-", - "T11771-", - "T11772-", - "C11773-", - "A11774-", - "T11775-", - "C11776-", - "G11777-", - "T11778-", - "G11779-", - "T11780-", - "A11781-", - "A11782-", - "G11783-", - "A11784-", - "A11785-", - "T11786-", - "C11787-", - "A11788-", - "A11789-", - "T11790-", - "A11791-", - "T11792-", - "T11793-", - "A11794-", - "A11795-", - "T11796-", - "A11797-", - "T11798-", - "T11799-", - "T11800-", - "C11801-", - "T11802-", - "A11803-", - "A11804-", - "A11805-", - "G11806-", - "T11807-", - "A11808-", - "T11809-", - "C11810-", - "T11811-", - "G11812-", - "T11813-", - "G11814-", - "T11815-", - "A11816-", - "T11817-", - "A11818-", - "G11819-", - "C11820-", - "C11821-", - "T11822-", - "C11823-", - "T11824-", - "T11825-", - "T11826-", - "A11827-", - "T11828-", - "T11829-", - "T11830-", - "A11831-", - "C11832-", - "C11833-", - "A11834-", - "C11835-", - "A11836-", - "G11837-", - "C11838-", - "T11839-", - "C11840-", - "C11841-", - "A11842-", - "T11843-", - "A11844-", - "T11845-", - "T11846-", - "C11847-", - "C11848-", - "A11849-", - "A11850-", - "C11851-", - "A11852-", - "T11853-", - "G11854-", - "C11855-", - "A11856-", - "T11857-", - "T11858-", - "C11859-", - "C11860-", - "A11861-", - "C11862-", - "T11863-", - "A11864-", - "G11865-", - "A11866-", - "G11867-", - "G11868-", - "G11869-", - "A11870-", - "T11871-", - "A11872-", - "T11873-", - "C11874-", - "G11875-", - "A11876-", - "T11877-", - "A11878-", - "T11879-", - "C11880-", - "G11881-", - "C11882-", - "C11883-", - "G11884-", - "A11885-", - "A11886-", - "T11887-", - "G11888-", - "T11889-", - "C11890-", - "A11891-", - "T11892-", - "A11893-", - "T11894-", - "A11895-", - "C11896-", - "T11897-", - "C11898-", - "A11899-", - "A11900-", - "T11901-", - "T11902-", - "A11903-", - "G11904-", - "T11905-", - "A11906-", - "T11907-", - "A11908-", - "T11909-", - "G11910-", - "T11911-", - "T11912-", - "G11913-", - "G11914-", - "A11915-", - "G11916-", - "G11917-", - "A11918-", - "C11919-", - "A11920-", - "T11921-", - "C11922-", - "C11923-", - "G11924-", - "A11925-", - "G11926-", - "T11927-", - "T11928-", - "C11929-", - "A11930-", - "T11931-", - "T11932-", - "G11933-", - "T11934-", - "T11935-", - "T11936-", - "T11937-", - "C11938-", - "A11939-", - "A11940-", - "T11941-", - "A11942-", - "T11943-", - "C11944-", - "A11945-", - "A11946-", - "A11947-", - "G11948-", - "A11949-", - "G11950-", - "A11951-", - "T11952-", - "G11953-", - "G11954-", - "T11955-", - "T11956-", - "T11957-", - "C11958-", - "C11959-", - "T11960-", - "T11961-", - "A11962-", - "T11963-", - "C11964-", - "A11965-", - "T11966-", - "T11967-", - "T11968-", - "C11969-", - "T11970-", - "C11971-", - "C11972-", - "A11973-", - "T11974-", - "A11975-", - "G11976-", - "T11977-", - "G11978-", - "G11979-", - "T11980-", - "A11981-", - "C11982-", - "A11983-", - "A11984-", - "T11985-", - "A11986-", - "C11987-", - "T11988-", - "A11989-", - "C11990-", - "A11991-", - "C11992-", - "A11993-", - "T11994-", - "T11995-", - "A11996-", - "T11997-", - "T11998-", - "C11999-", - "C12000-", - "G12001-", - "T12002-", - "A12003-", - "C12004-", - "G12005-", - "G12006-", - "C12007-", - "T12008-", - "T12009-", - "T12010-", - "C12011-", - "C12012-", - "A12013-", - "T12014-", - "T12015-", - "C12016-", - "T12017-", - "C12018-", - "C12019-", - "A12020-", - "A12021-", - "A12022-", - "A12023-", - "A12024-", - "C12025-", - "A12026-", - "A12027-", - "T12028-", - "T12029-", - "T12030-", - "T12031-", - "A12032-", - "C12033-", - "C12034-", - "A12035-", - "A12036-", - "A12037-", - "T12038-", - "C12039-", - "T12040-", - "A12041-", - "A12042-", - "A12043-", - "T12044-", - "C12045-", - "T12046-", - "A12047-", - "C12048-", - "A12049-", - "T12050-", - "C12051-", - "T12052-", - "T12053-", - "T12054-", - "A12055-", - "T12056-", - "T12057-", - "G12058-", - "T12059-", - "A12060-", - "T12061-", - "C12062-", - "T12063-", - "A12064-", - "T12065-", - "A12066-", - "A12067-", - "T12068-", - "C12069-", - "A12070-", - "C12071-", - "T12072-", - "A12073-", - "T12074-", - "T12075-", - "T12076-", - "A12077-", - "G12078-", - "A12079-", - "T12080-", - "A12081-", - "A12082-", - "T12083-", - "C12084-", - "A12085-", - "G12086-", - "C12087-", - "C12088-", - "A12089-", - "T12090-", - "A12091-", - "A12092-", - "T12093-", - "T12094-", - "C12095-", - "C12096-", - "T12097-", - "C12098-", - "G12099-", - "A12100-", - "G12101-", - "T12102-", - "G12103-", - "C12104-", - "A12105-", - "A12106-", - "C12107-", - "A12108-", - "T12109-", - "G12110-", - "T12111-", - "T12112-", - "A12113-", - "G12114-", - "A12115-", - "T12116-", - "C12117-", - "G12118-", - "T12119-", - "C12120-", - "T12121-", - "A12122-", - "T12123-", - "A12124-", - "T12125-", - "A12126-", - "T12127-", - "G12128-", - "A12129-", - "A12130-", - "T12131-", - "A12132-", - "A12133-", - "G12134-", - "C12135-", - "C12136-", - "G12137-", - "T12138-", - "G12139-", - "T12140-", - "T12141-", - "A12142-", - "T12143-", - "C12144-", - "T12145-", - "A12146-", - "T12147-", - "T12148-", - "C12149-", - "C12150-", - "T12151-", - "T12152-", - "T12153-", - "C12154-", - "A12155-", - "T12156-", - "T12157-", - "A12158-", - "A12159-", - "C12160-", - "A12161-", - "A12162-", - "T12163-", - "T12164-", - "T12165-", - "A12166-", - "A12167-", - "C12168-", - "G12169-", - "A12170-", - "T12171-", - "G12172-", - "T12173-", - "C12174-", - "T12175-", - "A12176-", - "T12177-", - "A12178-", - "T12179-", - "C12180-", - "T12181-", - "A12182-", - "T12183-", - "A12184-", - "T12185-", - "G12186-", - "A12187-", - "G12188-", - "A12189-", - "T12190-", - "G12191-", - "A12192-", - "C12193-", - "T12194-", - "T12195-", - "A12196-", - "A12197-", - "T12198-", - "A12199-", - "T12200-", - "A12201-", - "A12202-", - "T12203-", - "A12204-", - "T12205-", - "T12206-", - "G12207-", - "A12208-", - "A12209-", - "G12210-", - "A12211-", - "G12212-", - "C12213-", - "T12214-", - "G12215-", - "T12216-", - "A12217-", - "C12218-", - "A12219-", - "A12220-", - "T12221-", - "A12222-", - "G12223-", - "T12224-", - "T12225-", - "T12226-", - "T12227-", - "T12228-", - "A12229-", - "T12230-", - "C12231-", - "T12232-", - "A12233-", - "T12234-", - "A12235-", - "G12236-", - "A12237-", - "A12238-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "-196601A", - "-196602A", - "-196603A", - "A196616T" - ], - "OPG023": [ - "S221X", - "S222-", - "I223-", - "D224-", - "K225-", - "N226-", - "Y227-", - "C228-", - "T229-", - "A230-", - "L231-", - "Q232-", - "Y233-", - "Y234-", - "I235-", - "K236-", - "S237-", - "S238-", - "H239-", - "I240-", - "D241-", - "I242-", - "D243-", - "I244-", - "V245-", - "K246-", - "L247-", - "L248-", - "M249-", - "K250-", - "G251-", - "I252-", - "D253-", - "N254-", - "T255-", - "A256-", - "Y257-", - "S258-", - "Y259-", - "I260-", - "D261-", - "D262-", - "L263-", - "T264-", - "C265-", - "C266-", - "T267-", - "R268-", - "G269-", - "I270-", - "M271-", - "A272-", - "D273-", - "Y274-", - "L275-", - "N276-", - "S277-", - "D278-", - "Y279-", - "R280-", - "Y281-", - "N282-", - "K283-", - "D284-", - "V285-", - "D286-", - "L287-", - "D288-", - "L289-", - "V290-", - "K291-", - "L292-", - "F293-", - "L294-", - "E295-", - "N296-", - "G297-", - "K298-", - "P299-", - "Y300-", - "G301-", - "I302-", - "M303-", - "C304-", - "S305-", - "I306-", - "V307-", - "P308-", - "L309-", - "W310-", - "R311-", - "N312-", - "D313-", - "K314-", - "E315-", - "T316-", - "I317-", - "S318-", - "L319-", - "I320-", - "L321-", - "K322-", - "T323-", - "M324-", - "N325-", - "S326-", - "D327-", - "V328-", - "L329-", - "Q330-", - "H331-", - "I332-", - "L333-", - "I334-", - "E335-", - "Y336-", - "M337-", - "T338-", - "F339-", - "G340-", - "D341-", - "I342-", - "D343-", - "I344-", - "P345-", - "L346-", - "V347-", - "E348-", - "C349-", - "M350-", - "L351-", - "E352-", - "Y353-", - "G354-", - "A355-", - "V356-", - "V357-", - "N358-", - "K359-", - "E360-", - "A361-", - "I362-", - "H363-", - "R364-", - "Y365-", - "F366-", - "R367-", - "N368-", - "I369-", - "N370-", - "I371-", - "D372-", - "S373-", - "Y374-", - "T375-", - "M376-", - "K377-", - "Y378-", - "L379-", - "L380-", - "K381-", - "K382-", - "E383-", - "G384-", - "G385-", - "D386-", - "A387-", - "V388-", - "N389-", - "H390-", - "L391-", - "D392-", - "D393-", - "G394-", - "E395-", - "I396-", - "P397-", - "I398-", - "G399-", - "H400-", - "L401-", - "C402-", - "E403-", - "S404-", - "N405-", - "Y406-", - "G407-", - "C408-", - "Y409-", - "N410-", - "F411-", - "Y412-", - "T413-", - "Y414-", - "T415-", - "Y416-", - "K417-", - "K418-", - "G419-", - "L420-", - "C421-", - "D422-", - "M423-", - "S424-", - "Y425-", - "V426-", - "C427-", - "P428-", - "I429-", - "L430-", - "S431-", - "T432-", - "I433-", - "N434-", - "I435-", - "C436-", - "L437-", - "P438-", - "Y439-", - "L440-", - "K441-", - "D442-", - "I443-", - "N444-", - "M445-", - "I446-", - "D447-", - "K448-", - "R449-", - "G450-", - "E451-", - "T452-", - "L453-", - "L454-", - "H455-", - "K456-", - "A457-", - "V458-", - "R459-", - "Y460-", - "N461-", - "K462-", - "Q463-", - "S464-", - "L465-", - "V466-", - "S467-", - "L468-", - "L469-", - "L470-", - "E471-", - "S472-", - "G473-", - "S474-", - "D475-", - "V476-", - "N477-", - "I478-", - "R479-", - "S480-", - "N481-", - "N482-", - "G483-", - "Y484-", - "T485-", - "C486-", - "I487-", - "T488-", - "I489-", - "A490-", - "I491-", - "N492-", - "E493-", - "S494-", - "R495-", - "N496-", - "I497-", - "E498-", - "L499-", - "L500-", - "K501-", - "M502-", - "L503-", - "L504-", - "C505-", - "H506-", - "K507-", - "P508-", - "T509-", - "L510-", - "D511-", - "C512-", - "V513-", - "I514-", - "D515-", - "S516-", - "L517-", - "S518-", - "E519-", - "V520-", - "S521-", - "N522-", - "I523-", - "V524-", - "D525-", - "*661X" - ] - }, - "labels": { - "aa": "OPG023: S221X, S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-, *661X" - } - } - }, - { - "name": "MPX_96X1Vd_9000218", - "node_attrs": { - "div": 556, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-03-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPX_96X1Vd_9000218" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415196" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ] - } - } - }, - { - "name": "MPX_VghSe2_9000318", - "node_attrs": { - "div": 559, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPX_VghSe2_9000318" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415259" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G97390A", - "A104165C", - "C151050T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG117": [ - "D448N" - ] - }, - "labels": { - "aa": "OPG117: D448N" - } - } - }, - { - "name": "MPX_i0Eo3X_9000331", - "node_attrs": { - "div": 560, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPX_i0Eo3X_9000331" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415269" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C23567T", - "C67289T", - "G67527A", - "G77052A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG085": [ - "E415K" - ] - }, - "labels": { - "aa": "OPG085: E415K" - } - } - }, - { - "name": "hMPXV-CH-38212023/2022", - "node_attrs": { - "div": 556, - "author": { - "author": "Laubscher,F., Chudzinsk,V., Cordey,S., Schibler,M., Kaiser,L., Renzoni,A.", - "value": "Laubscher,F., Chudzinsk,V., Cordey,S., Schibler,M., Kaiser,L., Renzoni,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University Hospitals of Geneva, Laboratory of Virology" - }, - "date": { - "value": "2022-05-30" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "hMPXV-CH-38212023/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP422245" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Switzerland" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ] - } - } - }, - { - "name": "hMPXV/Austria/MUW1540386/2022", - "node_attrs": { - "div": 558, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "date": { - "value": "2022-08-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1540386/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP422343" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Austria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C102355T", - "C113923T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG121": [ - "S189L" - ], - "OPG133": [ - "D592N" - ] - }, - "labels": { - "aa": "OPG121: S189L; OPG133: D592N" - } - } - }, - { - "name": "hMPX/Human/USA/CA-LACPHL-MA00011/2022", - "node_attrs": { - "div": 558, - "author": { - "author": "Hemarajata,P., Green,N.M.", - "value": "Hemarajata,P., Green,N.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-07-22" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "hMPX/Human/USA/CA-LACPHL-MA00011/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP440584" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G59905A", - "G131350A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG080": [ - "S705F" - ] - }, - "labels": { - "aa": "OPG080: S705F" - } - } - }, - { - "name": "9000448", - "node_attrs": { - "div": 558, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "9000448" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536811" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C95004T", - "G111541A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG130": [ - "S121F" - ] - }, - "labels": { - "aa": "OPG130: S121F" - } - } - }, - { - "name": "Monkeypox/PT0402/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-07-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "Monkeypox/PT0402/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555498" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C42272T", - "C49892T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C153993T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG063": [ - "E473K" - ] - }, - "labels": { - "aa": "OPG063: E473K" - } - } - }, - { - "name": "Monkeypox/PT0520/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-18" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "Monkeypox/PT0520/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555591" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C20709T", - "G23661A", - "C84428T", - "A136513-", - "T136514-", - "C136515-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "-196603A" - ], - "OPG036": [ - "R119K" - ], - "OPG039": [ - "S153F" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG036: R119K; OPG039: S153F; OPG153: D385-" - } - } - }, - { - "name": "Monkeypox/PT0563/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-09-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "Monkeypox/PT0563/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555634" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C28104T", - "C28175T", - "G112246A", - "C125152T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C162012T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG044": [ - "S5L" - ], - "OPG131": [ - "D103N" - ] - }, - "labels": { - "aa": "OPG044: S5L; OPG131: D103N" - } - } - }, - { - "name": "Slovenia-MPXV-24-2022", - "node_attrs": { - "div": 558, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "Slovenia-MPXV-24-2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605566" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594A", - "-595T", - "C167944T", - "C180273A", - "T196367-", - "G196368-", - "T196369-" - ], - "OPG001": [ - "C245-" - ], - "OPG193": [ - "S204L" - ], - "OPG208": [ - "F336L" - ] - }, - "labels": { - "aa": "OPG001: C245-; OPG193: S204L; OPG208: F336L" - } - } - }, - { - "name": "Slovenia-MPXV-33-2022", - "node_attrs": { - "div": 556, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "Slovenia-MPXV-33-2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605575" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "A192374T" - ] - } - } - }, - { - "name": "Slovenia-MPXV-41-2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "Slovenia-MPXV-41-2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605582" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C126-", - "-595T", - "C27187T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG043": [ - "D257N" - ] - }, - "labels": { - "aa": "OPG043: D257N" - } - } - }, - { - "name": "Slovenia-MPXV-43-2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "Slovenia-MPXV-43-2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605584" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T10-", - "-595T", - "C8385T", - "T33995A", - "A86934G", - "G91904A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG052": [ - "M1L" - ] - }, - "labels": { - "aa": "OPG052: M1L" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI469", - "node_attrs": { - "div": 560, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI469" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP626107" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G54664A", - "A87268G", - "C105222T", - "G125815A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-" - ], - "OPG109": [ - "V727A" - ], - "OPG147": [ - "S58F" - ] - }, - "labels": { - "aa": "OPG109: V727A; OPG147: S58F" - } - } - }, - { - "name": "ANT_INS_MPX_0039_L", - "node_attrs": { - "div": 558, - "author": { - "author": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M.", - "value": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "date": { - "value": "2022-07-29" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "ANT_INS_MPX_0039_L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP693649" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A267-", - "T268-", - "G269-", - "G127058A", - "G136194A", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG148": [ - "R358K" - ], - "OPG153": [ - "H492Y" - ] - }, - "labels": { - "aa": "OPG148: R358K; OPG153: H492Y" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI553", - "node_attrs": { - "div": 556, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI553" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP715833" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A" - ] - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-097661/2022", - "node_attrs": { - "div": 556, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-097661/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP747053" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ] - } - } - }, - { - "name": "MPXV_USA_2022_CA0012", - "node_attrs": { - "div": 556, - "author": { - "author": "Gigante,C., Ventura,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nash,J., Li,Y.", - "value": "Gigante,C., Ventura,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nash,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV_USA_2022_CA0012" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ320511" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "Monkeypox virus/Human/USA/CA-LACPHL-MA00378/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-10-11" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "Monkeypox virus/Human/USA/CA-LACPHL-MA00378/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ330983" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G15683A", - "C102758T", - "C104028T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "C179853T", - "G184416A" - ], - "OPG122": [ - "P111S" - ], - "OPG123": [ - "G348E" - ], - "OPG210": [ - "D1021N" - ] - }, - "labels": { - "aa": "OPG122: P111S; OPG123: G348E; OPG210: D1021N" - } - } - }, - { - "name": "hMpxV/USA/CA-CDPH-1MPX1000114/2022", - "node_attrs": { - "div": 556, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "date": { - "value": "2022-08-10" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "hMpxV/USA/CA-CDPH-1MPX1000114/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ348862" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "hMPXV-CH-38292866/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Laubscher,F., Chudzinsk,V., Schibler,M., Kaiser,L., Renzoni,A.", - "value": "Laubscher,F., Chudzinsk,V., Schibler,M., Kaiser,L., Renzoni,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University Hospitals of Geneva, Laboratory of Virology" - }, - "date": { - "value": "2022-06-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "hMPXV-CH-38292866/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ411312" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Switzerland" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C87764T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG109": [ - "E562K" - ] - }, - "labels": { - "aa": "OPG109: E562K" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI715", - "node_attrs": { - "div": 557, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-10-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI715" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ451900" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G21655A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG037": [ - "S260L" - ] - }, - "labels": { - "aa": "OPG037: S260L" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI716", - "node_attrs": { - "div": 562, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-10-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI716" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ451901" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C2315T", - "G21250A", - "G40586A", - "C55859T", - "C93755T", - "G146821A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G160267A", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "G194895A" - ], - "OPG002": [ - "G146E" - ], - "OPG037": [ - "S395F" - ], - "OPG074": [ - "V423I" - ] - }, - "labels": { - "aa": "OPG002: G146E; OPG037: S395F; OPG074: V423I" - } - } - }, - { - "name": "NY-NYCPHL-000685", - "node_attrs": { - "div": 558, - "author": { - "author": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-05-07" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "NY-NYCPHL-000685" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468627" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C99831T", - "C142957T", - "T150544-", - "A150545-", - "T150546-", - "G150547-", - "A150548-", - "A150549-", - "G150550-", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558A", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00460/2023", - "node_attrs": { - "div": 559, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2023-01-23" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00460/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503837" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C43487T", - "C71729T", - "C101983T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG063": [ - "D68N" - ], - "OPG121": [ - "S65L" - ] - }, - "labels": { - "aa": "OPG063: D68N; OPG121: S65L" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI727", - "node_attrs": { - "div": 556, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI727" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ547754" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A" - ] - } - } - }, - { - "name": "hMpxV/USA/CACDPH1MPX1000174/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "date": { - "value": "2022-12-23" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "hMpxV/USA/CACDPH1MPX1000174/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ547882" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C565-", - "A566-", - "T567-", - "C3850T", - "T39315A", - "C132440T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "G193360A", - "G196581-", - "T196582-", - "C196583-" - ], - "OPG003": [ - "R253Q" - ], - "OPG057": [ - "D294V" - ] - }, - "labels": { - "aa": "OPG003: R253Q; OPG057: D294V" - } - } - }, - { - "name": "INMI-14732022", - "node_attrs": { - "div": 559, - "author": { - "author": "Rueca,M., Tucci,F.G., Mazzotta,V., Gramigna,G., Gruber,C.E.M., Fabeni,L., Giombini,E., Matusali,G., Pinnetti,C., Mariano,A., Butera,O., Specchiarello,E., Mondi,A., Lanini,S., Carletti,F., Girardi,E., Vaia,F., Nicastri,E., Antinori,A., Maggi,F.", - "value": "Rueca,M., Tucci,F.G., Mazzotta,V., Gramigna,G., Gruber,C.E.M., Fabeni,L., Giombini,E., Matusali,G., Pinnetti,C., Mariano,A., Butera,O., Specchiarello,E., Mondi,A., Lanini,S., Carletti,F., Girardi,E., Vaia,F., Nicastri,E., Antinori,A., Maggi,F." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute for Infectious Diseases \"L. Spallanzani\" - IRCCS, Laboratory of Virology" - }, - "date": { - "value": "2022-08-11" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "INMI-14732022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ570420" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Italy" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C45203T", - "C88917T", - "C130606T" - ] - } - } - }, - { - "name": "INMI-22872022", - "node_attrs": { - "div": 558, - "author": { - "author": "Rueca,M., Tucci,F.G., Mazzotta,V., Gramigna,G., Gruber,C.E.M., Fabeni,L., Giombini,E., Matusali,G., Pinnetti,C., Mariano,A., Butera,O., Specchiarello,E., Mondi,A., Lanini,S., Carletti,F., Girardi,E., Vaia,F., Nicastri,E., Antinori,A., Maggi,F.", - "value": "Rueca,M., Tucci,F.G., Mazzotta,V., Gramigna,G., Gruber,C.E.M., Fabeni,L., Giombini,E., Matusali,G., Pinnetti,C., Mariano,A., Butera,O., Specchiarello,E., Mondi,A., Lanini,S., Carletti,F., Girardi,E., Vaia,F., Nicastri,E., Antinori,A., Maggi,F." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute for Infectious Diseases \"L. Spallanzani\" - IRCCS, Laboratory of Virology" - }, - "date": { - "value": "2022-08-22" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "INMI-22872022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ570421" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Italy" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C106275T", - "G111562A" - ], - "OPG130": [ - "S114F" - ] - }, - "labels": { - "aa": "OPG130: S114F" - } - } - }, - { - "name": "MPXV/Spain/HUNSC_ITER_0006b/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Munoz-Barrera,A., Ciuffreda,L., Alcoba-Florez,J., Rubio-Rodriguez,L.A., Rodriguez-Perez,H., Gil-Campesino,H., Garcia-Martinez de Artola,D., Salas-Hernandez,J., Rodriguez-Nunez,J., Inigo-Campos,A., Garcia-Olivares,V., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C.", - "value": "Munoz-Barrera,A., Ciuffreda,L., Alcoba-Florez,J., Rubio-Rodriguez,L.A., Rodriguez-Perez,H., Gil-Campesino,H., Garcia-Martinez de Artola,D., Salas-Hernandez,J., Rodriguez-Nunez,J., Inigo-Campos,A., Garcia-Olivares,V., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division" - }, - "date": { - "value": "2022-07-01" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Spain/HUNSC_ITER_0006b/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ581848" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-133169T", - "-133170T", - "-133171T", - "-133172C", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C174264T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV/Spain/HUNSC_ITER_0007b/2022", - "node_attrs": { - "div": 558, - "author": { - "author": "Munoz-Barrera,A., Ciuffreda,L., Alcoba-Florez,J., Rubio-Rodriguez,L.A., Rodriguez-Perez,H., Gil-Campesino,H., Garcia-Martinez de Artola,D., Salas-Hernandez,J., Rodriguez-Nunez,J., Inigo-Campos,A., Garcia-Olivares,V., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C.", - "value": "Munoz-Barrera,A., Ciuffreda,L., Alcoba-Florez,J., Rubio-Rodriguez,L.A., Rodriguez-Perez,H., Gil-Campesino,H., Garcia-Martinez de Artola,D., Salas-Hernandez,J., Rodriguez-Nunez,J., Inigo-Campos,A., Garcia-Olivares,V., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division" - }, - "date": { - "value": "2022-07-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Spain/HUNSC_ITER_0007b/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ581849" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A52777C", - "C150418T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T169409C", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG071": [ - "Y554*" - ] - }, - "labels": { - "aa": "OPG071: Y554*" - } - } - }, - { - "name": "MPXV/human/Taiwan/110-093354/2023", - "node_attrs": { - "div": 564, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "date": { - "value": "2023-03-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/human/Taiwan/110-093354/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ672580" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Taiwan" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C39503G", - "G43620A", - "A44076G", - "G45563A", - "T69121C", - "T80764C", - "A130204G", - "A143123G", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG057": [ - "K231N" - ], - "OPG064": [ - "F608S" - ], - "OPG087": [ - "Y89H" - ], - "OPG104": [ - "N86D" - ], - "OPG164": [ - "T116A" - ] - }, - "labels": { - "aa": "OPG057: K231N; OPG064: F608S; OPG087: Y89H; OPG104: N86D; OPG164: T116A" - } - } - }, - { - "name": "MPXV/human/Taiwan/110-122438/2023", - "node_attrs": { - "div": 559, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "date": { - "value": "2023-03-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/human/Taiwan/110-122438/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ721951" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Taiwan" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133089-", - "T133090-", - "T133091-", - "T133092-", - "T133093-", - "T133094-", - "T133095-", - "T133096-", - "T133097-", - "T133098-", - "T133099-", - "T149983A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G160358A", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "A184479G", - "G193496T", - "A193498T", - "A193748G", - "T194019G", - "T194021A", - "G194086A" - ], - "OPG003": [ - "K298N", - "E299V", - "C473G", - "R495K" - ], - "OPG176": [ - "S59T" - ], - "OPG210": [ - "R1042G" - ] - }, - "labels": { - "aa": "OPG003: K298N, E299V, C473G, R495K; OPG176: S59T; OPG210: R1042G" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00485/2023", - "node_attrs": { - "div": 562, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2023-03-11" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00485/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ918696" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G30285A", - "G37487A", - "C71193T", - "G119839A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C161690T", - "C177865T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG047": [ - "P304S" - ], - "OPG137": [ - "E80K" - ], - "OPG188": [ - "S32F" - ], - "OPG205": [ - "S737F" - ] - }, - "labels": { - "aa": "OPG047: P304S; OPG137: E80K; OPG188: S32F; OPG205: S737F" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00487/2023", - "node_attrs": { - "div": 561, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2023-02-20" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00487/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ918698" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G66587A", - "G106113A", - "G143857A", - "C144237T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179227-", - "T179228-", - "T179229-", - "A179230-", - "T179231-", - "A179232-", - "T179233-", - "A179234-", - "C179235-", - "A179236-", - "T179237-", - "T179238-", - "A179239-", - "T179240-", - "A179241-", - "T179242-", - "A179243-", - "T179244-", - "C189810T" - ], - "OPG165": [ - "S241L" - ] - }, - "labels": { - "aa": "OPG165: S241L" - } - } - }, - { - "name": "case1_skin", - "node_attrs": { - "div": 560, - "author": { - "author": "Raymenants,J., Van Gestel,L., Coppens,J., de Block,T., Bangwen,E., Rutgers,J., Hens,M., De Vos,E., Coppens,S., Keyaerts,E., Andre,E., Rezende,A.M., Van Esbroeck,M., Vercauteren,K., Liesenborghs,L.", - "value": "Raymenants,J., Van Gestel,L., Coppens,J., de Block,T., Bangwen,E., Rutgers,J., Hens,M., De Vos,E., Coppens,S., Keyaerts,E., Andre,E., Rezende,A.M., Van Esbroeck,M., Vercauteren,K., Liesenborghs,L." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "date": { - "value": "2022-09-06" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "case1_skin" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ973327" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C111391T", - "C119654T", - "T133094-", - "T133095-", - "T133096-", - "T133097-", - "T133098-", - "T133099-", - "C152191T", - "T171948-", - "T171949-", - "C171950-", - "A171951-", - "C176178T", - "A178665-", - "C178666-", - "C178667-", - "T178668-", - "A178669-", - "A178670-", - "C178671-", - "T178672-", - "T178673-", - "C178674-", - "T178675-", - "G178676-", - "A178677-", - "A178678-", - "C178679-", - "T178680-", - "G178681-", - "G178682-", - "A178683-", - "A178684-", - "C178685-", - "T178686-", - "A178687-", - "T178688-", - "A178689-", - "A178690-", - "A178691-", - "T178692-", - "C178693-", - "C178694-", - "A178695-", - "G178696-" - ], - "OPG130": [ - "C171Y" - ], - "OPG137": [ - "S18L" - ], - "OPG199": [ - "F321-", - "I322X", - "*345X" - ], - "OPG205": [ - "H175Y" - ] - }, - "labels": { - "aa": "OPG130: C171Y; OPG137: S18L; OPG199: F321-, I322X, *345X; OPG205: H175Y" - } - } - }, - { - "name": "MPXV/UZ_REGA_26", - "node_attrs": { - "div": 557, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-07-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_26" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR030937" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T98627C", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG118": [ - "V61A" - ] - }, - "labels": { - "aa": "OPG118: V61A" - } - } - }, - { - "name": "MPXV/UZ_REGA_45", - "node_attrs": { - "div": 556, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-08-02" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_45" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035651" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_74", - "node_attrs": { - "div": 557, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-06-03" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_74" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035680" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A40037G", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_79", - "node_attrs": { - "div": 556, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-06-30" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_79" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035685" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T149487-", - "A149488-", - "C149489-", - "G149490-", - "T149491-", - "T149492-", - "G149493-", - "A149494-", - "A149495-", - "C149496-", - "A149497-", - "A149498-", - "G149499-", - "T149500-", - "C149501-", - "C149502-", - "A149503-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG175": [ - "Y16-", - "V17-", - "E18-", - "Q19-", - "V20-", - "H21X", - "*126X" - ] - }, - "labels": { - "aa": "OPG175: Y16-, V17-, E18-, Q19-, V20-, H21X, *126X" - } - } - }, - { - "name": "MPXV/UZ_REGA_84", - "node_attrs": { - "div": 556, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-08-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_84" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035690" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T150532-", - "T150533-", - "T150534-", - "T150535-", - "T150536-", - "T150537-", - "T150538-", - "T150539-", - "A150540-", - "T150541-", - "A150542-", - "G150543-", - "T150544-", - "A150545-", - "T150546-", - "G150547-", - "A150548-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_87", - "node_attrs": { - "div": 556, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-08-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_87" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035693" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_92", - "node_attrs": { - "div": 556, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-07-27" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_92" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035698" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_93", - "node_attrs": { - "div": 557, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-06-30" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_93" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035699" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C10015A", - "T155417-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_100", - "node_attrs": { - "div": 560, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-06-02" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_100" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035706" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G18442A", - "G98456A", - "C101656T", - "G170981A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG118": [ - "G4E" - ] - }, - "labels": { - "aa": "OPG118: G4E" - } - } - }, - { - "name": "MPXV/UZ_REGA_123", - "node_attrs": { - "div": 558, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-09-20" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_123" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035729" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C19277T", - "C166803T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG192": [ - "P25S" - ] - }, - "labels": { - "aa": "OPG192: P25S" - } - } - }, - { - "name": "MPXV/UZ_REGA_231/Belgium/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-08-12" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_231/Belgium/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR095049" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133098-", - "T133099-", - "T149487-", - "A149488-", - "C149489-", - "G149490-", - "T149491-", - "T149492-", - "G149493-", - "A149494-", - "A149495-", - "C149496-", - "A149497-", - "A149498-", - "G149499-", - "T149500-", - "C149501-", - "C149502-", - "A149503-", - "C168943T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG175": [ - "Y16-", - "V17-", - "E18-", - "Q19-", - "V20-", - "H21X", - "*126X" - ] - }, - "labels": { - "aa": "OPG175: Y16-, V17-, E18-, Q19-, V20-, H21X, *126X" - } - } - }, - { - "name": "RNA", - "node_attrs": { - "div": 557, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava" - }, - "date": { - "value": "2022-07-25" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "RNA" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OX291435" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovakia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G57076A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A164529-", - "C164530-", - "C164531-", - "A164532-", - "T164533-", - "C164534-", - "T164535-", - "T164536-", - "T164537-", - "G164538-", - "A164539-", - "A164540-", - "A164541-", - "A164542-", - "T164543-", - "T164544-", - "A164545-", - "T164546-", - "G164547-", - "A164548-", - "T164549-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A196604-" - ], - "OPG074": [ - "S17L" - ], - "OPG189": [ - "R399X", - "P400-", - "S401-", - "L402-", - "K403-", - "I404-", - "M405-", - "I406X", - "*562X" - ] - }, - "labels": { - "aa": "OPG074: S17L; OPG189: R399X, P400-, S401-, L402-, K403-, I404-, M405-, I406X, *562X" - } - } - }, - { - "name": "RNA", - "node_attrs": { - "div": 558, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava" - }, - "date": { - "value": "2022-07-25" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "RNA" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OX291780" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovakia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G67955A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A173274-", - "T173275-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "G184141A", - "A196604-" - ], - "OPG085": [ - "P193S" - ], - "OPG210": [ - "G929D" - ] - }, - "labels": { - "aa": "OPG085: P193S; OPG210: G929D" - } - } - }, - { - "name": "RNA", - "node_attrs": { - "div": 557, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava" - }, - "date": { - "value": "2022-08-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "RNA" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OX297403" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovakia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G64522A", - "T133098-", - "T133099-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A196604-" - ] - } - } - }, - { - "name": "RNA", - "node_attrs": { - "div": 557, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava" - }, - "date": { - "value": "2022-08-26" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "RNA" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OX336004" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovakia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C94836T", - "T133097-", - "T133098-", - "T133099-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A196604-" - ] - } - } - }, - { - "name": "MPX_96X1Vd_9000217", - "node_attrs": { - "div": 556, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-03-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPX_96X1Vd_9000217" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415195" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ] - } - } - }, - { - "name": "4061", - "node_attrs": { - "div": 556, - "author": { - "author": "de la Hoz-Sanchez,B., Lopez-Ortiz,M., Gutierrez-Arroyo,A., Roces-Alvarez,P., Lazaro-Peona,F., Dahdouh,E., Bloise,I., Garcia-Rodriguez,J., Mingorance,J.", - "value": "de la Hoz-Sanchez,B., Lopez-Ortiz,M., Gutierrez-Arroyo,A., Roces-Alvarez,P., Lazaro-Peona,F., Dahdouh,E., Bloise,I., Garcia-Rodriguez,J., Mingorance,J." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Hospital Universitario La Paz, Microbiology" - }, - "date": { - "value": "2022-05-20" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "4061" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON838940" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ] - } - } - }, - { - "name": "Monkeypox/PT0013/2022", - "node_attrs": { - "div": 556, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J.D., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Carvalho,I.L., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J.D., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Carvalho,I.L., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal" - }, - "date": { - "value": "2022-05-20" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "Monkeypox/PT0013/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON649723" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "hMPXV-IHU00003", - "node_attrs": { - "div": 556, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "date": { - "value": "2022-07-04" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "hMPXV-IHU00003" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP382480" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI385", - "node_attrs": { - "div": 556, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI385" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP523987" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_30", - "node_attrs": { - "div": 556, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-07-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_30" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR030941" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPX/UZ_REGA_5/Belgium/2022", - "node_attrs": { - "div": 556, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Rega Institute, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-05-27" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPX/UZ_REGA_5/Belgium/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880421" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV_IRBA22-14", - "node_attrs": { - "div": 556, - "author": { - "author": "Jarjaval,F., Nolent,F., Criqui,A., Chapus,C., Lamer,O., Ferraris,O., Gorge,O.", - "value": "Jarjaval,F., Nolent,F., Criqui,A., Chapus,C., Lamer,O., Ferraris,O., Gorge,O." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IRBA, D.DNRBC/D.2MI/U.BACT" - }, - "date": { - "value": "2022-05-20" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV_IRBA22-14" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON755040" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133094-", - "T133095-", - "T133096-", - "T133097-", - "T133098-", - "T133099-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV_ISR001_2022", - "node_attrs": { - "div": 556, - "author": { - "author": "Israeli,O., Guedj-Dana,Y., Lazar,S., Shifman,O., Erez,N., Weiss,S., Paran,N., Israely,T., Schuster,O., Zvi,A., Beth-Din,A., Cohen Gihon,I.", - "value": "Israeli,O., Guedj-Dana,Y., Lazar,S., Shifman,O., Erez,N., Weiss,S., Paran,N., Israely,T., Schuster,O., Zvi,A., Beth-Din,A., Cohen Gihon,I." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel" - }, - "date": { - "value": "2022-05-20" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV_ISR001_2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON649879" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Israel" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "MPXV_USA_2022_MA001", - "node_attrs": { - "div": 556, - "author": { - "author": "Gigante,C.M., Smole,S., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Brown,C., Li,Y.", - "value": "Gigante,C.M., Smole,S., Seabolt,M.H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Brown,C., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV_USA_2022_MA001" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON563414" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ] - } - } - }, - { - "name": "MPX-42/Finland/2022", - "node_attrs": { - "div": 556, - "author": { - "author": "Kant,R., Smura,T., Vauhkonen,H., Vapalahti,O., Sironen,T.", - "value": "Kant,R., Smura,T., Vauhkonen,H., Vapalahti,O., Sironen,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Helsinki, Department of Virology, Faculty of Medicine" - }, - "date": { - "value": "2022-05-31" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPX-42/Finland/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON782022" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Finland" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "NODE_0000097", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G70190A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG089": [ - "E109K" - ] - }, - "labels": { - "aa": "OPG089: E109K" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_CA002", - "node_attrs": { - "div": 558, - "author": { - "author": "Gigante,C.M., Ventura,J., Seabolt,M.H., Zhao,H., Wilkins,K., Respress,J., Howard,D., Batra,D., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nash,J., Li,Y.", - "value": "Gigante,C.M., Ventura,J., Seabolt,M.H., Zhao,H., Wilkins,K., Respress,J., Howard,D., Batra,D., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nash,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV_USA_2022_CA002" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON954773" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G83568A" - ], - "OPG105": [ - "A815T" - ] - }, - "labels": { - "aa": "OPG105: A815T" - } - } - }, - { - "name": "MPXV/UZ_REGA_128", - "node_attrs": { - "div": 558, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-10-10" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_128" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035734" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G164038A", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG189": [ - "E236K" - ] - }, - "labels": { - "aa": "OPG189: E236K" - } - } - } - ] - }, - { - "name": "NODE_0000098", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C142607T" - ], - "OPG163": [ - "H136Y" - ] - }, - "labels": { - "aa": "OPG163: H136Y" - } - }, - "children": [ - { - "name": "MP03CHUAC", - "node_attrs": { - "div": 558, - "author": { - "author": "Aja-Macaya,P., Rumbo-Feal,S., Poza,M., Canizares,A., Vallejo,J.A., Bou,G.", - "value": "Aja-Macaya,P., Rumbo-Feal,S., Poza,M., Canizares,A., Vallejo,J.A., Bou,G." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Biomedical research institute (INIBIC), Microbiology" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MP03CHUAC" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP120938" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C118421T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG136": [ - "M389I" - ] - }, - "labels": { - "aa": "OPG136: M389I" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00341/2022", - "node_attrs": { - "div": 564, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-10-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00341/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP920679" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C5081T", - "G51559A", - "G71170A", - "C77397T", - "T96060C", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C154408T", - "G166314A", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "G192129A", - "A196429-", - "G196430-", - "A196431-" - ], - "NBT03_gp175": [ - "R359K" - ], - "OPG015": [ - "R359K" - ], - "OPG191": [ - "D52N" - ] - }, - "labels": { - "aa": "NBT03_gp175: R359K; OPG015: R359K; OPG191: D52N" - } - } - } - ] - }, - { - "name": "NODE_0000099", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G102694A" - ] - } - }, - "children": [ - { - "name": "hMPXV/Austria/MUW1539124/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "date": { - "value": "2022-08-02" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1539124/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP422342" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Austria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G28490A", - "C110960T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG044": [ - "D134N" - ] - }, - "labels": { - "aa": "OPG044: D134N" - } - } - }, - { - "name": "hMpxV/USA/CACDPH1MPX1000155/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "date": { - "value": "2022-12-15" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "hMpxV/USA/CACDPH1MPX1000155/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ547873" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A530-", - "G531-", - "A532-", - "A140155T", - "A140156G", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG159": [ - "N130C" - ] - }, - "labels": { - "aa": "OPG159: N130C" - } - } - } - ] - }, - { - "name": "NODE_0000101", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C156205T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-" - ] - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00357/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-11-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00357/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP920695" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A469-", - "A470-", - "G471-", - "G23685A", - "C33499T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "A196604-" - ], - "OPG039": [ - "S145F" - ], - "OPG051": [ - "E51K" - ] - }, - "labels": { - "aa": "OPG039: S145F; OPG051: E51K" - } - } - }, - { - "name": "Monkeypox virus/Human/USA/CA-LACPHL-MA00395/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-12-23" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "Monkeypox virus/Human/USA/CA-LACPHL-MA00395/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ330974" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - } - ] - }, - { - "name": "NODE_0000102", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C81194T", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "-196603A" - ] - } - }, - "children": [ - { - "name": "NY-NYCPHL-000603", - "node_attrs": { - "div": 559, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-08-01" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "NY-NYCPHL-000603" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468909" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C149364T", - "G149730A", - "T150544-", - "A150545-", - "T150546-", - "G150547-", - "A150548-", - "A150549-", - "G150550-", - "-150558A" - ], - "OPG174": [ - "G11E" - ], - "OPG175": [ - "D97N" - ] - }, - "labels": { - "aa": "OPG174: G11E; OPG175: D97N" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00464/2023", - "node_attrs": { - "div": 559, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2023-01-26" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00464/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503840" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C6310T", - "A39482C", - "-150551G", - "-150552A", - "-150558T", - "A170123-", - "T170124-", - "A170125-", - "A170126-", - "A177657-", - "T177658-", - "C177659-", - "A177660-", - "C177661-", - "T177662-", - "A177663-", - "A177664-", - "T177665-", - "A177666-", - "A177667-", - "T177668-", - "A177669-", - "T177670-", - "A177671-", - "A177672-", - "C177673-", - "A177674-", - "C177675-", - "T177676-", - "A177677-", - "T177678-", - "A177679-", - "C177680-", - "G177681-", - "A177682-", - "C177683-", - "A177684-", - "C177685-", - "T177686-", - "A177687-", - "T177688-", - "T177689-", - "A177690-", - "T177691-", - "A177692-", - "A177693-", - "A177694-", - "T177695-", - "A177696-", - "A177697-", - "T177698-", - "A177699-", - "A177700-", - "G177701-", - "T177702-", - "C177703-", - "A177704-", - "G177705-", - "A177706-", - "G177707-", - "T177708-", - "T177709-", - "T177710-", - "C177711-", - "C177712-", - "T177713-", - "A177714-", - "T177715-", - "A177716-", - "C177717-", - "G177718-", - "T177719-", - "C177720-", - "G177721-", - "T177722-", - "G177723-", - "T177724-", - "A177725-", - "A177726-", - "A177727-", - "C177728-", - "G177729-", - "A177730-", - "C177731-", - "A177732-", - "A177733-", - "A177734-", - "C177735-", - "A177736-", - "A177737-", - "T177738-", - "T177739-", - "A177740-", - "A177741-", - "T177742-", - "T177743-", - "A177744-", - "A177745-", - "T177746-", - "C177747-", - "T177748-", - "C177749-", - "A177750-", - "T177751-", - "A177752-", - "A177753-", - "G190900A" - ], - "NBT03_gp174": [ - "R164K" - ], - "OPG057": [ - "H238Q" - ], - "OPG198": [ - "Y29X", - "K30X", - "*283X" - ], - "OPG205": [ - "I668-", - "T669-", - "N670-", - "N671-", - "I672-", - "T673-", - "L674-", - "Y675-", - "D676-", - "T677-", - "I678-", - "I679-", - "N680-", - "N681-", - "K682-", - "S683-", - "E684-", - "F685-", - "P686-", - "I687-", - "R688-", - "R689-", - "V690-", - "N691-", - "D692-", - "K693-", - "Q694-", - "L695-", - "I696-", - "N697-", - "L698-", - "I699-", - "K700X", - "*788X" - ] - }, - "labels": { - "aa": "NBT03_gp174: R164K; OPG057: H238Q; OPG198: Y29X, K30X, *283X; OPG205: I668-, T669-, N670-, N671-, I672-, T673-, L674-, Y675-, D676-, T677-, I678-, I679-, N680-, N681-, K682-, S683-, E684-, F685-, P686-, I687-, R688-, R689-, V690-, N691-, D692-, K693-, Q694-, L695-, I696-, N697-, L698-, I699-, K700X, *788X" - } - } - } - ] - }, - { - "name": "NODE_0000120", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G169928A", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-" - ], - "OPG197": [ - "D87N" - ] - }, - "labels": { - "aa": "OPG197: D87N" - } - }, - "children": [ - { - "name": "Monkeypox/BR0001/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Claro,I.M., de Lima,E.L., Romano,C.M., Candido,D.S., Lindoso,J.A.L., Barra,L.A.C., Borges,L.M.S., Medeiros,L.A., Tomishige,M.Y.S., Ramundo,M.S., Moutinho,T., da Silva,A.J.D., Rodrigues,C.C.M., de Azevedo,L.C.F., Villas-Boas,L.S., da Silva,C.A.M., Coletti,T.M., O'Toole,A., Quick,J., Loman,N., Rambaut,A., Faria,N.R., Figueiredo-Mello,C., Sabino,E.C.", - "value": "Claro,I.M., de Lima,E.L., Romano,C.M., Candido,D.S., Lindoso,J.A.L., Barra,L.A.C., Borges,L.M.S., Medeiros,L.A., Tomishige,M.Y.S., Ramundo,M.S., Moutinho,T., da Silva,A.J.D., Rodrigues,C.C.M., de Azevedo,L.C.F., Villas-Boas,L.S., da Silva,C.A.M., Coletti,T.M., O'Toole,A., Quick,J., Loman,N., Rambaut,A., Faria,N.R., Figueiredo-Mello,C., Sabino,E.C." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Imperial College London, School of Public Health" - }, - "date": { - "value": "2022-06-07" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "Monkeypox/BR0001/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON751962" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Brazil" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T591-", - "A592-", - "-594T", - "G10118A", - "C15004T", - "T133094-", - "T133095-", - "T133096-", - "T133097-", - "T133098-", - "T133099-", - "T172973-", - "A172974-", - "T172975-", - "A172976-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG021": [ - "E178K" - ] - }, - "labels": { - "aa": "OPG021: E178K" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI057", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Stocker,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Stocker,H., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI057" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON813254" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G58518A", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - } - ] - }, - { - "name": "NODE_0000121", - "node_attrs": { - "div": 556, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": {} - }, - "children": [ - { - "name": "NODE_0000100", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C22982T", - "C49265T", - "C70780T", - "C124495T", - "C150392T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG038": [ - "E60K" - ], - "OPG176": [ - "S195F" - ] - }, - "labels": { - "aa": "OPG038: E60K; OPG176: S195F" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI440", - "node_attrs": { - "div": 561, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI440" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP594204" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C179163-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI501", - "node_attrs": { - "div": 563, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI501" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP626139" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G149818A", - "C160312T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T" - ], - "OPG176": [ - "D4N" - ] - }, - "labels": { - "aa": "OPG176: D4N" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000103", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C156429T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - }, - "children": [ - { - "name": "Monkeypox/PT0134/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-07-11" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "Monkeypox/PT0134/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP324457" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G162265A", - "C165278T", - "C188566T", - "-196603A" - ], - "OPG188": [ - "E224K" - ], - "OPG190": [ - "H53Y" - ] - }, - "labels": { - "aa": "OPG188: E224K; OPG190: H53Y" - } - } - }, - { - "name": "NODE_0000104", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C65571T", - "G144988A" - ] - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-3450/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-06-03" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3450/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880549" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/CAN/UN-NML-4014/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Griffiths,E., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Griffiths,E., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-07-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-4014/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP270025" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C45103T", - "G74933A", - "G131867A" - ], - "OPG064": [ - "E266K" - ], - "OPG095": [ - "R44Q" - ], - "OPG151": [ - "E982K" - ] - }, - "labels": { - "aa": "OPG064: E266K; OPG095: R44Q; OPG151: E982K" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000105", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G190695A" - ], - "NBT03_gp174": [ - "E96K" - ] - }, - "labels": { - "aa": "NBT03_gp174: E96K" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI717", - "node_attrs": { - "div": 562, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-11-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI717" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ451902" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C3602T", - "C53342T", - "C124495T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G159789A", - "C170573T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "G193608A" - ], - "OPG003": [ - "E336K" - ], - "OPG071": [ - "R366K" - ], - "OPG198": [ - "S179L" - ] - }, - "labels": { - "aa": "OPG003: E336K; OPG071: R366K; OPG198: S179L" - } - } - }, - { - "name": "NODE_0000106", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C34432T" - ], - "OPG053": [ - "E87K" - ] - }, - "labels": { - "aa": "OPG053: E87K" - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-24812-L", - "node_attrs": { - "div": 560, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-09-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-24812-L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP642382" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C67439T", - "G154993A", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ], - "OPG085": [ - "D365N" - ] - }, - "labels": { - "aa": "OPG085: D365N" - } - } - }, - { - "name": "HRYC_MPXV001", - "node_attrs": { - "div": 561, - "author": { - "author": "Ponce-Alonso,M., Martinez-Garcia,L., Olavarrieta,L., Galan,J.C.", - "value": "Ponce-Alonso,M., Martinez-Garcia,L., Olavarrieta,L., Galan,J.C." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Hospital Ramon y Cajal, Microbiology" - }, - "date": { - "value": "2022-09-21" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "HRYC_MPXV001" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR126131" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C11747-", - "C48324T", - "G101294A", - "C141757T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG023": [ - "G385X", - "*661X" - ], - "OPG120": [ - "S152L" - ] - }, - "labels": { - "aa": "OPG023: G385X, *661X; OPG120: S152L" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000107", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.20" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G53326A", - "T133099-", - "C164385T", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "C187620T" - ] - }, - "labels": { - "clade": "B.1.20" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_TX0040", - "node_attrs": { - "div": 559, - "author": { - "author": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Sheth,M.R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y.", - "value": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Sheth,M.R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-10-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.20" - }, - "strain_original": { - "value": "MPXV_USA_2022_TX0040" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ320441" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-196603A" - ] - } - } - }, - { - "name": "NODE_0000108", - "node_attrs": { - "div": 563, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.20" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "T597-", - "T598-", - "T599-", - "T600-", - "C20453T", - "-133099T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T164946C", - "-173292A", - "-173293T", - "G177398A", - "C177899T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A196604-", - "A196605-", - "A196606-", - "A196607-", - "A196608-" - ] - } - }, - "children": [ - { - "name": "hMpxV/USA/IL-RIPHL-MPXV-050-0059/2023", - "node_attrs": { - "div": 565, - "author": { - "author": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S.", - "value": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)" - }, - "date": { - "value": "2023-05-23" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.20" - }, - "strain_original": { - "value": "hMpxV/USA/IL-RIPHL-MPXV-050-0059/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR160417" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G43661A", - "C57550T", - "A136513-", - "T136514-", - "C136515-" - ], - "OPG063": [ - "L10F" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG063: L10F; OPG153: D385-" - } - } - }, - { - "name": "hMpxV/USA/IL-RIPHL-MPXV-050-0060/2023", - "node_attrs": { - "div": 563, - "author": { - "author": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S.", - "value": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)" - }, - "date": { - "value": "2023-05-31" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.20" - }, - "strain_original": { - "value": "hMpxV/USA/IL-RIPHL-MPXV-050-0060/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR257449" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "hMpxV/USA/IL-RIPHL-MPXV-050-0068/2023", - "node_attrs": { - "div": 567, - "author": { - "author": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S.", - "value": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)" - }, - "date": { - "value": "2023-06-14" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.20" - }, - "strain_original": { - "value": "hMpxV/USA/IL-RIPHL-MPXV-050-0068/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR257450" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C2313T", - "T117118C", - "G170233A", - "G189274A", - "G194897A" - ], - "OPG002": [ - "D147N" - ], - "OPG005": [ - "V26I" - ], - "OPG136": [ - "M824V" - ], - "OPG198": [ - "D66N" - ] - }, - "labels": { - "aa": "OPG002: D147N; OPG005: V26I; OPG136: M824V; OPG198: D66N" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000109", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.18" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C43706T", - "T124690C", - "C141757T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ] - }, - "labels": { - "clade": "B.1.18" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-083401/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.18" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-083401/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP628451" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NY-NYCPHL-001086", - "node_attrs": { - "div": 560, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-07-06" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.18" - }, - "strain_original": { - "value": "NY-NYCPHL-001086" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469264" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C127388T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG149": [ - "R65C" - ] - }, - "labels": { - "aa": "OPG149: R65C" - } - } - }, - { - "name": "NY-NYCPHL-000155", - "node_attrs": { - "div": 559, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-06-27" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.18" - }, - "strain_original": { - "value": "NY-NYCPHL-000155" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ504405" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133099-", - "T150544-", - "A150545-", - "T150546-", - "G150547-", - "A150548-", - "A150549-", - "G150550-", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558A", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "NODE_0000110", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.18" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G67758A", - "C170049T" - ] - } - }, - "children": [ - { - "name": "VAC_INS_MPX_0958_L", - "node_attrs": { - "div": 561, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "date": { - "value": "2022-10-13" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.18" - }, - "strain_original": { - "value": "VAC_INS_MPX_0958_L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP819952" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "LBMB-UTP_MP-025_VAC", - "node_attrs": { - "div": 565, - "author": { - "author": "Lopez,P.A., Orjuela,M., Tabares,F.A., Anacona,J.D., Zuluaga-Velez,A., Sepulveda-Arias,J.C.", - "value": "Lopez,P.A., Orjuela,M., Tabares,F.A., Anacona,J.D., Zuluaga-Velez,A., Sepulveda-Arias,J.C." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud" - }, - "date": { - "value": "2022-11-15" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.18" - }, - "strain_original": { - "value": "LBMB-UTP_MP-025_VAC" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ148474" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C128242T", - "G144572A", - "C166940T", - "C168829T" - ], - "OPG150": [ - "S155F" - ] - }, - "labels": { - "aa": "OPG150: S155F" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000111", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A47741-", - "T47742-", - "T47743-", - "A47744-", - "G47745-", - "G47746-", - "A47750-", - "T47766-", - "A47767-", - "A47770-", - "C47772-", - "A47773-", - "C47775-", - "T47776-", - "A47777-", - "T47963-", - "A47964-", - "T47965-", - "G47966-", - "G49679-", - "A49707-", - "C62258-", - "A62259-", - "G62260-", - "T62261-", - "T62262-", - "C62305-", - "A62306-", - "A62307-", - "A62308-", - "G62309-", - "C62325-", - "C62326-", - "T62327-", - "A62328-", - "G62329-", - "T62330-", - "T62331-", - "G62332-", - "T62333-", - "A62334-", - "T62335-", - "A62336-", - "C62337-", - "T62338-", - "G62339-", - "A62340-", - "G62341-", - "A62342-", - "A62343-", - "T62344-", - "T62345-", - "G62346-", - "T62372-", - "T62373-", - "T62374-", - "T62375-", - "C62376-", - "A62404-", - "C62405-", - "T62406-", - "G62407-", - "G62408-", - "A62409-", - "A62410-", - "A62411-", - "A62412-", - "C62413-", - "T62414-", - "A62432-", - "A62433-", - "G62434-", - "T62435-", - "A62436-", - "T62437-", - "A62438-", - "T62532-", - "A62533-", - "G62552-", - "A62553-", - "G62554-", - "G62571-", - "C62572-", - "T62573-", - "T62574-", - "C62575-", - "T62576-", - "A62577-", - "G62578-", - "T62599-", - "A62623-", - "C62624-", - "T62625-", - "A62626-", - "T62627-", - "G62758-", - "T62759-", - "G62760-", - "G62761-", - "A62762-", - "A62763-", - "T62764-", - "T62765-", - "G62766-", - "A62767-", - "A62768-", - "G62769-", - "A62770-", - "T62771-", - "T62772-", - "C62773-", - "T62774-", - "A62775-", - "A62776-", - "T62777-", - "G62778-", - "G62779-", - "A62780-", - "T62781-", - "G62782-", - "A62783-", - "T62784-", - "G62785-", - "T62786-", - "T62787-", - "C62788-", - "T62789-", - "A62790-", - "C62791-", - "C62792-", - "T62793-", - "A62794-", - "T62795-", - "T62796-", - "T62797-", - "C62798-", - "A62799-", - "T62800-", - "C62801-", - "C62802-", - "G62803-", - "A62804-", - "T62805-", - "T62818-", - "C62819-", - "C62820-", - "A62821-", - "G62854-", - "G62855-", - "T62856-", - "A62857-", - "G62858-", - "T62859-", - "C62860-", - "T62861-", - "C62862-", - "T62863-", - "C62864-", - "T62865-", - "T62866-", - "T62867-", - "C62868-", - "G62869-", - "A62892-", - "T62893-", - "A62894-", - "C62895-", - "G62896-", - "A62897-", - "G62898-", - "T62899-", - "C62900-", - "A62901-", - "T62902-", - "T62903-", - "A62904-", - "T62905-", - "A62906-", - "T62907-", - "A62908-", - "C62909-", - "T62910-", - "C62911-", - "C62912-", - "T62931-", - "A62943-", - "T62944-", - "C62945-", - "G62946-", - "A62947-", - "A62965-", - "T62966-", - "C62967-", - "G62968-", - "G62980-", - "A62981-", - "A62982-", - "T62983-", - "C62984-", - "C62985-", - "G62986-", - "G62987-", - "A62988-", - "A62989-", - "C62990-", - "A62991-", - "T62992-", - "T63023-", - "G63024-", - "G63025-", - "T63026-", - "A63027-", - "A63028-", - "G63029-", - "A63030-", - "A63031-", - "A63042-", - "T63075-", - "T63076-", - "G63077-", - "A63078-", - "G63079-", - "A63080-", - "C63081-", - "T63082-", - "T63083-", - "G63084-", - "A63085-", - "T63086-", - "A63102-", - "T63103-", - "T63104-", - "C63143-", - "G63144-", - "T63145-", - "C63146-", - "G63147-", - "A63148-", - "C63149-", - "G63150-", - "C63151-", - "C63152-", - "A63153-", - "A63167-", - "T63168-", - "G63169-", - "G63170-", - "A63171-", - "G63172-", - "T63173-", - "T63239-", - "C63240-", - "T63241-", - "C63242-", - "G63243-", - "T63244-", - "A63245-", - "C63246-", - "G63247-", - "T63255-", - "T63256-", - "C63257-", - "C63258-", - "A63259-", - "T63260-", - "G63261-", - "A63262-", - "T63263-", - "C63264-", - "A63265-", - "A63266-", - "G63267-", - "A63268-", - "G63269-", - "T63270-", - "G63271-", - "A63272-", - "T63273-", - "T63274-", - "T63275-", - "G63276-", - "A63277-", - "G63278-", - "A63279-", - "A63280-", - "C63281-", - "A63282-", - "T63283-", - "C63284-", - "C63285-", - "A63311-", - "C63312-", - "A63313-", - "G63314-", - "T63315-", - "T63328-", - "A63329-", - "A63330-", - "T63331-", - "T63347-", - "A63348-", - "C63365-", - "G63366-", - "T63367-", - "T63368-", - "T63369-", - "A63370-", - "A63371-", - "T63385-", - "C63386-", - "T63387-", - "A63388-", - "A63389-", - "C63390-", - "G63391-", - "G63392-", - "A63393-", - "G63394-", - "A63395-", - "C63396-", - "A63397-", - "A63398-", - "T63399-", - "T63400-", - "T63401-", - "T63402-", - "T63403-", - "T63404-", - "G63405-", - "G63406-", - "T63407-", - "A63408-", - "G63409-", - "G63410-", - "T63411-", - "T63412-", - "T63413-", - "T63414-", - "A63415-", - "G63416-", - "A63417-", - "G63418-", - "A63419-", - "C63420-", - "T63421-", - "T63422-", - "T63423-", - "G63424-", - "A63425-", - "A63426-", - "G63427-", - "C63428-", - "T63429-", - "A63430-", - "C63431-", - "T63432-", - "T63433-", - "G63434-", - "T63435-", - "T63436-", - "T63437-", - "A63438-", - "A63439-", - "C63440-", - "A63441-", - "A63442-", - "A63443-", - "G63444-", - "T63445-", - "T63446-", - "A63447-", - "T63448-", - "T63449-", - "C63450-", - "A63451-", - "T63452-", - "C63453-", - "G63454-", - "T63455-", - "C63456-", - "C112408T", - "T178558-", - "G178559-", - "A178560-", - "T178561-", - "T178562-", - "A178563-", - "T178564-", - "A178565-", - "C178566-", - "A178567-", - "T178568-", - "C178569-", - "G178570-", - "G178571-", - "T178572-", - "A178573-", - "C178574-", - "A178575-" - ], - "OPG068": [ - "E493X", - "T503X", - "*568X" - ], - "OPG081": [ - "L8X", - "T9-", - "A10X", - "*80X" - ], - "OPG082": [ - "M1-", - "N2-", - "N3-", - "F4-", - "V5-", - "K6-", - "Q7-", - "V8-", - "A9-", - "S10-", - "K11-", - "S12-", - "L13-", - "K14-", - "P15-", - "T16-", - "K17-", - "K18-", - "L19-", - "S20-", - "P21-", - "L22-", - "D23X", - "L28-", - "N29-", - "E30X", - "F35X", - "N36X", - "Y41X", - "Y42X", - "G46X", - "L47-", - "F48X", - "E56X", - "D57-", - "V58-", - "L59-", - "K60-", - "S61-", - "L62-", - "L63-", - "I64-", - "M65-", - "E66-", - "A69X", - "Y70-", - "E71-", - "K72X", - "T94-", - "P95-", - "F96X", - "T100X", - "G101-", - "V102-", - "D103-", - "D104X", - "N117-", - "I123-", - "K124-", - "S125-", - "Q126-", - "N137X", - "V141X", - "L142-", - "T143-", - "T144X", - "N154X", - "V155-", - "P156-", - "D157-", - "S158X", - "S162X", - "I163X", - "F169X", - "D170-", - "I174X", - "G181-", - "V182-", - "Y183-", - "N184-", - "D185-", - "S186-", - "Y187-", - "P195X", - "K196-", - "E197-", - "R198-", - "L199-", - "P200X", - "L211X", - "E212X", - "L216X", - "S217-", - "D218-", - "E219-", - "I220-", - "G221-", - "R222-", - "T223-", - "S224-", - "S225-", - "I226-", - "R227-", - "I228-", - "F229-", - "N230-", - "S231-", - "T232X", - "I276-", - "V277X", - "N285X", - "S292X", - "R293-", - "S294-", - "T300X", - "H301X", - "L307X", - "Y339-", - "T340-", - "Y341X", - "S347-", - "F348-", - "P349-", - "V350X", - "K359X", - "K360-", - "K361X", - "V369X", - "N370-", - "S371-", - "Q372-", - "Y373-", - "T374-", - "T375-", - "R376-", - "L382-", - "*383X" - ], - "OPG083": [ - "D421-", - "D422-", - "E423-", - "*424-" - ], - "OPG131": [ - "L157F" - ] - }, - "labels": { - "aa": "OPG068: E493X, T503X, *568X; OPG081: L8X, T9-, A10X, *80X; OPG082: M1-, N2-, N3-, F4-, V5-, K6-, Q7-, V8-, A9-, S10-, K11-, S12-, L13-, K14-, P15-, T16-, K17-, K18-, L19-, S20-, P21-, L22-, D23X, L28-, N29-, E30X, F35X, N36X, Y41X, Y42X, G46X, L47-, F48X, E56X, D57-, V58-, L59-, K60-, S61-, L62-, L63-, I64-, M65-, E66-, A69X, Y70-, E71-, K72X, T94-, P95-, F96X, T100X, G101-, V102-, D103-, D104X, N117-, I123-, K124-, S125-, Q126-, N137X, V141X, L142-, T143-, T144X, N154X, V155-, P156-, D157-, S158X, S162X, I163X, F169X, D170-, I174X, G181-, V182-, Y183-, N184-, D185-, S186-, Y187-, P195X, K196-, E197-, R198-, L199-, P200X, L211X, E212X, L216X, S217-, D218-, E219-, I220-, G221-, R222-, T223-, S224-, S225-, I226-, R227-, I228-, F229-, N230-, S231-, T232X, I276-, V277X, N285X, S292X, R293-, S294-, T300X, H301X, L307X, Y339-, T340-, Y341X, S347-, F348-, P349-, V350X, K359X, K360-, K361X, V369X, N370-, S371-, Q372-, Y373-, T374-, T375-, R376-, L382-, *383X; OPG083: D421-, D422-, E423-, *424-; OPG131: L157F" - } - }, - "children": [ - { - "name": "19012023_anal", - "node_attrs": { - "div": 559, - "author": { - "author": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K.", - "value": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "date": { - "value": "2023-01-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "19012023_anal" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ672571" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-47741A", - "-47742T", - "-47743T", - "-47744A", - "-47745G", - "-47746G", - "-47750A", - "-47766T", - "-47767A", - "-47770A", - "-47772C", - "-47773A", - "-47775C", - "-47776T", - "-47777A", - "-47963T", - "-47964A", - "-47965T", - "-47966G", - "-49679G", - "-49707A", - "-62258C", - "-62259A", - "-62260G", - "-62261T", - "-62262T", - "-62305C", - "-62306A", - "-62307A", - "-62308A", - "-62309G", - "-62325C", - "-62326C", - "-62327T", - "-62328A", - "-62329G", - "-62330T", - "-62331T", - "-62332G", - "-62333T", - "-62334A", - "-62335T", - "-62336A", - "-62337C", - "-62338T", - "-62339G", - "-62340A", - "-62341G", - "-62342A", - "-62343A", - "-62344T", - "-62345T", - "-62346G", - "-62372T", - "-62373T", - "-62374T", - "-62375T", - "-62376C", - "-62404A", - "-62405C", - "-62406T", - "-62407G", - "-62408G", - "-62409A", - "-62410A", - "-62411A", - "-62412A", - "-62413C", - "-62414T", - "-62432A", - "-62433A", - "-62434G", - "-62435T", - "-62436A", - "-62437T", - "-62438A", - "-62532T", - "-62533A", - "-62552G", - "-62553A", - "-62554G", - "-62571G", - "-62572C", - "-62573T", - "-62574T", - "-62575C", - "-62576T", - "-62577A", - "-62578G", - "-62599T", - "-62623A", - "-62624C", - "-62625T", - "-62626A", - "-62627T", - "-62758G", - "-62759T", - "-62760G", - "-62761G", - "-62762A", - "-62763A", - "-62764T", - "-62765T", - "-62766G", - "-62767A", - "-62768A", - "-62769G", - "-62770A", - "-62771T", - "-62772T", - "-62773C", - "-62774T", - "-62775A", - "-62776A", - "-62777T", - "-62778G", - "-62779G", - "-62780A", - "-62781T", - "-62782G", - "-62783A", - "-62784T", - "-62785G", - "-62786T", - "-62787T", - "-62788C", - "-62789T", - "-62790A", - "-62791C", - "-62792C", - "-62793T", - "-62794A", - "-62795T", - "-62796T", - "-62797T", - "-62798C", - "-62799A", - "-62800T", - "-62801C", - "-62802C", - "-62803G", - "-62804A", - "-62805T", - "-62818T", - "-62819C", - "-62820C", - "-62821A", - "-62854G", - "-62855G", - "-62856T", - "-62857A", - "-62858G", - "-62859T", - "-62860C", - "-62861T", - "-62862C", - "-62863T", - "-62864C", - "-62865T", - "-62866T", - "-62867T", - "-62868C", - "-62869G", - "-62892A", - "-62893T", - "-62894A", - "-62895C", - "-62896G", - "-62897A", - "-62898G", - "-62899T", - "-62900C", - "-62901A", - "-62902T", - "-62903T", - "-62904A", - "-62905T", - "-62906A", - "-62907T", - "-62908A", - "-62909C", - "-62910T", - "-62911C", - "-62912C", - "-62931T", - "-62943A", - "-62944T", - "-62945C", - "-62946G", - "-62947A", - "-62965A", - "-62966T", - "-62967C", - "-62968G", - "-62980G", - "-62981A", - "-62982A", - "-62983T", - "-62984C", - "-62985C", - "-62986G", - "-62987G", - "-62988A", - "-62989A", - "-62990C", - "-62991A", - "-62992T", - "-63023T", - "-63024G", - "-63025G", - "-63026T", - "-63027A", - "-63028A", - "-63029G", - "-63030A", - "-63031A", - "-63042A", - "-63075T", - "-63076T", - "-63077G", - "-63078A", - "-63079G", - "-63080A", - "-63081C", - "-63082T", - "-63083T", - "-63084G", - "-63085A", - "-63086T", - "-63102A", - "-63103T", - "-63104T", - "-63143C", - "-63144G", - "-63145T", - "-63146C", - "-63147G", - "-63148A", - "-63149C", - "-63150G", - "-63151C", - "-63152C", - "-63153A", - "-63167A", - "-63168T", - "-63169G", - "-63170G", - "-63171A", - "-63172G", - "-63173T", - "-63239T", - "-63240C", - "-63241T", - "-63242C", - "-63243G", - "-63244T", - "-63245A", - "-63246C", - "-63247G", - "-63255T", - "-63256T", - "-63257C", - "-63258C", - "-63259A", - "-63260T", - "-63261G", - "-63262A", - "-63263T", - "-63264C", - "-63265A", - "-63266A", - "-63267G", - "-63268A", - "-63269G", - "-63270T", - "-63271G", - "-63272A", - "-63273T", - "-63274T", - "-63275T", - "-63276G", - "-63277A", - "-63278G", - "-63279A", - "-63280A", - "-63281C", - "-63282A", - "-63283T", - "-63284C", - "-63285C", - "-63311A", - "-63312C", - "-63313A", - "-63314G", - "-63315T", - "-63328T", - "-63329A", - "-63330A", - "-63331T", - "-63347T", - "-63348A", - "-63365C", - "-63366G", - "-63367T", - "-63368T", - "-63369T", - "-63370A", - "-63371A", - "-63385T", - "-63386C", - "-63387T", - "-63388A", - "-63389A", - "-63390C", - "-63391G", - "-63392G", - "-63393A", - "-63394G", - "-63395A", - "-63396C", - "-63397A", - "-63398A", - "-63399T", - "-63400T", - "-63401T", - "-63402T", - "-63403T", - "-63404T", - "-63405G", - "-63406G", - "-63407T", - "-63408A", - "-63409G", - "-63410G", - "-63411T", - "-63412T", - "-63413T", - "-63414T", - "-63415A", - "-63416G", - "-63417A", - "-63418G", - "-63419A", - "-63420C", - "-63421T", - "-63422T", - "-63423T", - "-63424G", - "-63425A", - "-63426A", - "-63427G", - "-63428C", - "-63429T", - "-63430A", - "-63431C", - "-63432T", - "-63433T", - "-63434G", - "-63435T", - "-63436T", - "-63437T", - "-63438A", - "-63439A", - "-63440C", - "-63441A", - "-63442A", - "-63443A", - "-63444G", - "-63445T", - "-63446T", - "-63447A", - "-63448T", - "-63449T", - "-63450C", - "-63451A", - "-63452T", - "-63453C", - "-63454G", - "-63455T", - "-63456C", - "G69989A", - "C117978T", - "T145492-", - "G145493-", - "A145494-", - "A145495-", - "G145496-", - "A145497-", - "A145498-", - "A145499-", - "T145500-", - "A145501-", - "A145502-", - "T145503-", - "T145504-", - "T145505-", - "C145506-", - "T145507-", - "A145508-", - "C145509-", - "A145646-", - "C145647-", - "A145648-", - "T145649-", - "T145650-", - "A145651-", - "G145652-", - "T145653-", - "A145654-", - "G145655-", - "T145656-", - "A145657-", - "T145658-", - "G145659-", - "C145660-", - "G145661-", - "G145662-", - "A145663-", - "A145664-", - "C145665-", - "C145666-", - "A145667-", - "A145668-", - "T145669-", - "A145670-", - "A145671-", - "C145672-", - "G145673-", - "G145674-", - "A145675-", - "A145676-", - "A145677-", - "T145678-", - "C145679-", - "C145680-", - "C145681-", - "A145682-", - "A145683-", - "A145684-", - "T145685-", - "G145686-", - "T145687-", - "T145688-", - "G145689-", - "G145690-", - "A145691-", - "A145692-", - "A145693-", - "A145694-", - "T145695-", - "A145696-", - "G145697-", - "A145698-", - "C145699-", - "G145700-", - "G145701-", - "T145702-", - "T145703-", - "C145704-", - "A145705-", - "T145706-", - "A145707-", - "C145708-", - "T145709-", - "A145710-", - "C145711-", - "C145712-", - "C145713-", - "A145714-", - "A145715-", - "A145716-", - "A145717-", - "C145718-", - "A145719-", - "T145720-", - "A145721-", - "T145722-", - "A145723-", - "G145724-", - "G145725-", - "T145726-", - "A145727-", - "G145728-", - "A145729-", - "G145730-", - "G145731-", - "A145732-", - "T145733-", - "A145734-", - "C145735-", - "G145736-", - "A145737-", - "T145738-", - "C145739-", - "A145740-", - "T145741-", - "C145742-", - "A145743-", - "A145744-", - "A145745-", - "A145746-", - "T145747-", - "A145748-", - "G145749-", - "C145750-", - "A145751-", - "A145752-", - "A145753-", - "G145754-", - "T145755-", - "A145756-", - "A145757-", - "C145758-", - "G145759-", - "A145760-", - "T145761-", - "A145762-", - "A145763-", - "T145764-", - "C145765-", - "A145766-", - "G145767-", - "T145768-", - "C145769-", - "A145770-", - "C145771-", - "A145772-", - "A145773-", - "T145774-", - "G145775-", - "A145776-", - "A145777-", - "T145778-", - "G145779-", - "T145780-", - "G145781-", - "T145782-", - "A145783-", - "C145784-", - "T145785-", - "A145786-", - "T145787-", - "C145788-", - "C145789-", - "G145790-", - "A145791-", - "C145792-", - "A145793-", - "T145794-", - "A145795-", - "A145796-", - "A145797-", - "C145798-", - "A145799-", - "T145800-", - "A145801-", - "T145802-", - "A145803-", - "A145804-", - "A145805-", - "A145806-", - "A145807-", - "G145808-", - "A145809-", - "A145810-", - "G145811-", - "G145812-", - "A145813-", - "A145814-", - "T145815-", - "T145816-", - "A145817-", - "A145818-", - "A145819-", - "C145820-", - "G145821-", - "A145822-", - "T145823-", - "G145824-", - "G145825-", - "A145826-", - "G145827-", - "A145828-", - "A145829-", - "G145830-", - "A145831-", - "T145832-", - "T145833-", - "T145834-", - "G145835-", - "A145836-", - "C145837-", - "G145838-", - "G145839-", - "A145840-", - "C145841-", - "C145842-", - "A145843-", - "T145844-", - "G145845-", - "T145846-", - "G145847-", - "G145848-", - "T145849-", - "T145850-", - "A145851-", - "T145852-", - "G145853-", - "A145854-", - "T145855-", - "T145856-", - "A145857-", - "A145858-", - "A145859-", - "C145860-", - "G145861-", - "A145862-", - "G145863-", - "T145864-", - "T145865-", - "A145866-", - "A145867-", - "G145868-", - "T145869-", - "T145870-", - "T145871-", - "T145872-", - "T145873-", - "T145874-", - "A145875-", - "A145876-", - "G145877-", - "A145878-", - "A145879-", - "G145880-", - "C145881-", - "C145882-", - "T145883-", - "T145884-", - "A145885-", - "G145886-", - "A145887-", - "A169725-", - "T169726-" - ], - "OPG068": [ - "X493E", - "X503T", - "X568*" - ], - "OPG081": [ - "X8L", - "-9T", - "X10A", - "X80*" - ], - "OPG082": [ - "-1M", - "-2N", - "-3N", - "-4F", - "-5V", - "-6K", - "-7Q", - "-8V", - "-9A", - "-10S", - "-11K", - "-12S", - "-13L", - "-14K", - "-15P", - "-16T", - "-17K", - "-18K", - "-19L", - "-20S", - "-21P", - "-22L", - "X23D", - "-28L", - "-29N", - "X30E", - "X35F", - "X36N", - "X41Y", - "X42Y", - "X46G", - "-47L", - "X48F", - "X56E", - "-57D", - "-58V", - "-59L", - "-60K", - "-61S", - "-62L", - "-63L", - "-64I", - "-65M", - "-66E", - "X69A", - "-70Y", - "-71E", - "X72K", - "-94T", - "-95P", - "X96F", - "X100T", - "-101G", - "-102V", - "-103D", - "X104D", - "-117N", - "-123I", - "-124K", - "-125S", - "-126Q", - "X137N", - "X141V", - "-142L", - "-143T", - "X144T", - "X154N", - "-155V", - "-156P", - "-157D", - "X158S", - "X162S", - "X163I", - "X169F", - "-170D", - "X174I", - "-181G", - "-182V", - "-183Y", - "-184N", - "-185D", - "-186S", - "-187Y", - "X195P", - "-196K", - "-197E", - "-198R", - "-199L", - "X200P", - "X211L", - "X212E", - "X216L", - "-217S", - "-218D", - "-219E", - "-220I", - "-221G", - "-222R", - "-223T", - "-224S", - "-225S", - "-226I", - "-227R", - "-228I", - "-229F", - "-230N", - "-231S", - "X232T", - "-276I", - "X277V", - "X285N", - "X292S", - "-293R", - "-294S", - "X300T", - "X301H", - "X307L", - "-339Y", - "-340T", - "X341Y", - "-347S", - "-348F", - "-349P", - "X350V", - "X359K", - "-360K", - "X361K", - "X369V", - "-370N", - "-371S", - "-372Q", - "-373Y", - "-374T", - "-375T", - "-376R", - "-382L", - "X383*" - ], - "OPG083": [ - "-421D", - "-422D", - "-423E", - "-424*" - ], - "OPG089": [ - "A42T" - ], - "OPG136": [ - "R537K" - ], - "OPG197": [ - "D19X", - "*101X" - ] - }, - "labels": { - "aa": "OPG068: X493E, X503T, X568*; OPG081: X8L, -9T, X10A, X80*; OPG082: -1M, -2N, -3N, -4F, -5V, -6K, -7Q, -8V, -9A, -10S, -11K, -12S, -13L, -14K, -15P, -16T, -17K, -18K, -19L, -20S, -21P, -22L, X23D, -28L, -29N, X30E, X35F, X36N, X41Y, X42Y, X46G, -47L, X48F, X56E, -57D, -58V, -59L, -60K, -61S, -62L, -63L, -64I, -65M, -66E, X69A, -70Y, -71E, X72K, -94T, -95P, X96F, X100T, -101G, -102V, -103D, X104D, -117N, -123I, -124K, -125S, -126Q, X137N, X141V, -142L, -143T, X144T, X154N, -155V, -156P, -157D, X158S, X162S, X163I, X169F, -170D, X174I, -181G, -182V, -183Y, -184N, -185D, -186S, -187Y, X195P, -196K, -197E, -198R, -199L, X200P, X211L, X212E, X216L, -217S, -218D, -219E, -220I, -221G, -222R, -223T, -224S, -225S, -226I, -227R, -228I, -229F, -230N, -231S, X232T, -276I, X277V, X285N, X292S, -293R, -294S, X300T, X301H, X307L, -339Y, -340T, X341Y, -347S, -348F, -349P, X350V, X359K, -360K, X361K, X369V, -370N, -371S, -372Q, -373Y, -374T, -375T, -376R, -382L, X383*; OPG083: -421D, -422D, -423E, -424*; OPG089: A42T; OPG136: R537K; OPG197: D19X, *101X" - } - } - }, - { - "name": "26012023_neck", - "node_attrs": { - "div": 562, - "author": { - "author": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K.", - "value": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "date": { - "value": "2023-01-26" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "26012023_neck" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ672573" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T2640-", - "G2641-", - "T2642-", - "A2643-", - "T2644-", - "T2645-", - "C2646-", - "G2647-", - "G6878A", - "C40894T", - "T47699-", - "A47700-", - "A47747-", - "C47748-", - "T47749-", - "C47751-", - "T47752-", - "A47753-", - "C47754-", - "T47755-", - "C47756-", - "T47757-", - "A47758-", - "G47759-", - "A47760-", - "A47761-", - "G47762-", - "A47763-", - "T47764-", - "A47765-", - "G47768-", - "C47769-", - "C47771-", - "T47774-", - "T47778-", - "T47779-", - "C47780-", - "C47781-", - "A47782-", - "A47783-", - "A47784-", - "T47785-", - "A47786-", - "A47787-", - "T47788-", - "C47789-", - "A47790-", - "G47791-", - "A47792-", - "A47793-", - "A47794-", - "A47795-", - "C47796-", - "T47797-", - "T47798-", - "A47799-", - "T47800-", - "A47801-", - "A47802-", - "A47803-", - "C47804-", - "T47805-", - "A47806-", - "T47807-", - "T47808-", - "C47809-", - "T47810-", - "C47811-", - "G47812-", - "G47813-", - "A47814-", - "C47815-", - "A47816-", - "T47817-", - "T47818-", - "T47819-", - "C47820-", - "A47821-", - "G47822-", - "T47823-", - "C47824-", - "A47825-", - "T47826-", - "T47827-", - "G47828-", - "G47829-", - "C47830-", - "G47946-", - "A47947-", - "T47948-", - "A47949-", - "T47950-", - "A47951-", - "G47952-", - "T47953-", - "T47954-", - "G47955-", - "A47956-", - "A47957-", - "T47958-", - "C47959-", - "A47960-", - "T47961-", - "G47962-", - "T48032-", - "T48033-", - "A48034-", - "T48060-", - "A48061-", - "G48062-", - "G48063-", - "A48112-", - "A48113-", - "T48114-", - "A48115-", - "G48116-", - "T48117-", - "A48161-", - "T48162-", - "A48163-", - "G48164-", - "T48165-", - "A48166-", - "G48167-", - "T48168-", - "G48169-", - "T48170-", - "A48171-", - "G48172-", - "T48173-", - "A48174-", - "T48175-", - "C48176-", - "A48177-", - "T48178-", - "A48179-", - "G48180-", - "A48181-", - "T48182-", - "A48183-", - "A48184-", - "C48185-", - "T48186-", - "C48187-", - "T48188-", - "C48189-", - "T48190-", - "T48191-", - "C48192-", - "T48193-", - "A48194-", - "T48195-", - "A48196-", - "A48197-", - "A48198-", - "A48199-", - "A48200-", - "A48201-", - "T48202-", - "G48203-", - "G48204-", - "A48205-", - "T48206-", - "T48207-", - "T48208-", - "T48209-", - "A48210-", - "T48211-", - "T48212-", - "C48213-", - "G48214-", - "T48215-", - "A48216-", - "G48217-", - "A48218-", - "A48219-", - "A48220-", - "G48221-", - "T48222-", - "A48223-", - "T48224-", - "C48225-", - "T48226-", - "A48289-", - "T48290-", - "A48318-", - "A48319-", - "G48320-", - "T48321-", - "A48322-", - "T48323-", - "C48324-", - "T48325-", - "A48326-", - "G48327-", - "T48366-", - "T48382-", - "T48383-", - "T48384-", - "T48385-", - "T48386-", - "G48387-", - "T48388-", - "T48389-", - "T48390-", - "T48391-", - "C48392-", - "A48415-", - "A48416-", - "G48417-", - "T48418-", - "A48419-", - "T48420-", - "A48421-", - "C48422-", - "G48423-", - "A48424-", - "A48425-", - "G48426-", - "C48427-", - "G48428-", - "G48429-", - "T48430-", - "T48431-", - "T48432-", - "A48571-", - "A48572-", - "T48573-", - "A48574-", - "C48575-", - "A48576-", - "T48577-", - "G48578-", - "G48579-", - "A48580-", - "C48581-", - "G48582-", - "A48583-", - "A48584-", - "T48585-", - "T48586-", - "A48587-", - "G48588-", - "G48589-", - "A48590-", - "G48591-", - "A48592-", - "A48593-", - "C48594-", - "T48595-", - "T48596-", - "A48597-", - "T48598-", - "A48599-", - "G48600-", - "G48601-", - "C48602-", - "G48603-", - "T48604-", - "A48605-", - "A48606-", - "A48607-", - "T48608-", - "T48609-", - "A48610-", - "T48611-", - "G48612-", - "A48613-", - "C48614-", - "T48615-", - "T48616-", - "A48617-", - "G48618-", - "T48619-", - "C48648-", - "C48649-", - "C48650-", - "A48651-", - "T48652-", - "C48653-", - "A48654-", - "A48655-", - "A48656-", - "G48657-", - "A48658-", - "T48659-", - "A48660-", - "T48661-", - "G48662-", - "G48663-", - "A48664-", - "A48665-", - "A48666-", - "T48667-", - "C48668-", - "A48669-", - "T48670-", - "T48671-", - "T48672-", - "T48673-", - "T48674-", - "A48760-", - "A48761-", - "G48762-", - "A48763-", - "T48764-", - "A48765-", - "C48766-", - "A48767-", - "G48768-", - "G48769-", - "C48770-", - "A48771-", - "T48772-", - "A48773-", - "G48774-", - "A48775-", - "G48776-", - "T48777-", - "T48778-", - "T48779-", - "G48780-", - "C48781-", - "G48782-", - "G48783-", - "A48784-", - "T48785-", - "A48786-", - "A48787-", - "T48788-", - "A48790T", - "G48798T", - "A48822-", - "C48823-", - "T48824-", - "G48825-", - "G48826-", - "T48827-", - "A48828-", - "G48829-", - "A48830-", - "A48831-", - "T48832-", - "A48833-", - "G48834-", - "T48835-", - "C48836-", - "C48837-", - "A48838-", - "T48839-", - "A48840-", - "G48841-", - "C48842-", - "A48843-", - "A48844-", - "T48845-", - "C48846-", - "T48847-", - "A48848-", - "A48849-", - "C48850-", - "A48851-", - "G48852-", - "A48853-", - "A48854-", - "A48855-", - "C48856-", - "G48857-", - "T48858-", - "T48859-", - "T48860-", - "A48861-", - "G48862-", - "G48863-", - "G48864-", - "A48865-", - "T48866-", - "T48867-", - "A48868-", - "T48869-", - "A48870-", - "T48871-", - "C48872-", - "T48873-", - "T48874-", - "T48875-", - "C48876-", - "C48877T", - "A48909-", - "A48910-", - "C48911-", - "G48912-", - "A48913-", - "A48914-", - "A48915-", - "G48916-", - "T48917-", - "A48918-", - "T48919-", - "T48968-", - "G48969-", - "A48970-", - "T48971-", - "A48972-", - "A48973-", - "A48974-", - "A48975-", - "T48976-", - "T48977-", - "C48978-", - "T48979-", - "T48980-", - "A48981-", - "G48982-", - "T48983-", - "T48984-", - "A48985-", - "T48986-", - "A48987-", - "T48988-", - "A48989-", - "T48990-", - "A48991-", - "C48992-", - "T48993-", - "C48994-", - "T48995-", - "G48996-", - "A48997-", - "G48998-", - "A48999-", - "T49000-", - "A49001-", - "A49002-", - "A49003-", - "A49004-", - "C49005-", - "A49006-", - "G49007-", - "G49008-", - "G49009-", - "A49010-", - "C49011-", - "G49012-", - "C49013-", - "G49014-", - "T49015-", - "T49016-", - "A49017-", - "A49018-", - "T49019-", - "A49020-", - "A49021-", - "A49022-", - "A49023-", - "A49024-", - "C49025-", - "A49026-", - "T49027-", - "G49028-", - "C49029-", - "T49030-", - "T49031-", - "A49032-", - "A49033-", - "G49034-", - "T49035-", - "T49156-", - "T49157-", - "A49158-", - "T49159-", - "T49160-", - "A49161-", - "G49162-", - "T49163-", - "T49164-", - "T49165-", - "T49166-", - "T49167-", - "A49168-", - "C49169-", - "A49170-", - "A49171-", - "A49172-", - "G49173-", - "C49174-", - "T49175-", - "A49176-", - "A49177-", - "T49178-", - "T49179-", - "T49180-", - "T49181-", - "A49182-", - "T49183-", - "T49184-", - "A49185-", - "A49186-", - "C49187-", - "G49188-", - "G49189-", - "T49190-", - "A49191-", - "A49192-", - "T49193-", - "A49194-", - "C49195-", - "A49196-", - "T49197-", - "T49198-", - "T49199-", - "A49200-", - "T49201-", - "T49202-", - "A49203-", - "G49204-", - "T49205-", - "G49206-", - "A49207-", - "T49208-", - "A49209-", - "G49210-", - "A49211-", - "A49212-", - "C49213-", - "G49214-", - "T49215-", - "T49216-", - "T49217-", - "A49218-", - "A49219-", - "C49220-", - "G49221-", - "A49222-", - "T49223-", - "G49224-", - "A49225-", - "C49226-", - "T49227-", - "T49228-", - "A49229-", - "T49230-", - "T49231-", - "C49232-", - "A49233-", - "G49234-", - "A49235-", - "G49236-", - "T49237-", - "T49238-", - "G49239-", - "T49240-", - "T49241-", - "G49242-", - "T49243-", - "T49244-", - "C49245-", - "A49246-", - "A49247-", - "A49248-", - "T49249-", - "A49250-", - "G49251-", - "A49252-", - "T49253-", - "C49254-", - "C49255-", - "C49256-", - "G49257-", - "A49258-", - "A49259-", - "T49260-", - "A49261-", - "T49262-", - "T49263-", - "T49264-", - "C49265-", - "G49266-", - "A49267-", - "T49268-", - "A49269-", - "A49270-", - "T49271-", - "G49272-", - "A49273-", - "A49274-", - "C49275-", - "G49276-", - "A49277-", - "A49278-", - "T49279-", - "T49280-", - "A49281-", - "T49282-", - "G49283-", - "T49284-", - "C49285-", - "T49286-", - "T49287-", - "T49288-", - "A49289-", - "T49290-", - "T49291-", - "C49292-", - "T49293-", - "A49294-", - "T49295-", - "A49296-", - "C49297-", - "G49298-", - "A49299-", - "G49300-", - "T49301-", - "G49302-", - "C49303-", - "T49304-", - "G49305-", - "C49306-", - "G49307-", - "G49308-", - "A49309-", - "C49310-", - "A49311-", - "T49312-", - "T49313-", - "A49314-", - "A49315-", - "A49316-", - "C49317-", - "G49318-", - "A49319-", - "T49320-", - "T49321-", - "T49322-", - "G49323-", - "A49324-", - "T49325-", - "G49326-", - "A49327-", - "G49328-", - "T49329-", - "T49330-", - "A49331-", - "G49332-", - "A49333-", - "T49334-", - "A49335-", - "T49336-", - "T49337-", - "A49338-", - "A49339-", - "T49340-", - "A49341-", - "A49342-", - "C49343-", - "A49344-", - "G49345-", - "T49346-", - "T49347-", - "A49348-", - "T49349-", - "A49350-", - "T49351-", - "A49352-", - "T49353-", - "C49354-", - "T49355-", - "A49356-", - "A49357-", - "G49397-", - "G49398-", - "A49399-", - "T49400-", - "G49401-", - "A49402-", - "T49403-", - "A49404-", - "T49405-", - "G49406-", - "A49407-", - "A49408-", - "G49409-", - "A49410-", - "T49473-", - "T49474-", - "G49475-", - "C49476-", - "A49477-", - "C49478-", - "G49479-", - "A49480-", - "G49481-", - "T49482-", - "C49483-", - "G49484-", - "G49485-", - "A49486-", - "T49487-", - "C49488-", - "C49489-", - "C49490-", - "A49491-", - "T49492-", - "G49493-", - "G49494-", - "T49495-", - "C49496-", - "A49497-", - "T49498-", - "A49499-", - "G49500-", - "A49501-", - "G49502-", - "A49503-", - "A49504-", - "C49505-", - "G49506-", - "G49507-", - "A49508-", - "A49509-", - "T49510-", - "A49511-", - "C49512-", - "T49513-", - "A49514-", - "A49515-", - "A49516-", - "G49517-", - "A49518-", - "A49519-", - "A49520-", - "C49521-", - "T49522-", - "G49523-", - "T49524-", - "C49525-", - "A49526-", - "T49527-", - "C49528-", - "T49529-", - "A49530-", - "T49531-", - "A49532-", - "A49533-", - "A49534-", - "A49535-", - "T49536-", - "C49537-", - "C49538-", - "A49539-", - "A49540-", - "G49541-", - "A49542-", - "G49543-", - "T49544-", - "A49545-", - "G49546-", - "A49547-", - "C49548-", - "G49549-", - "G49550-", - "C49551-", - "T49552-", - "G49553-", - "A49554-", - "A49555-", - "C49556-", - "T49557-", - "T49558-", - "G49559-", - "T49560-", - "T49561-", - "T49562-", - "A49563-", - "G49564-", - "C49565-", - "A49566-", - "A49567-", - "A49568-", - "A49569-", - "A49570-", - "C49571-", - "A49572-", - "T49573-", - "T49574-", - "T49575-", - "T49576-", - "A49577-", - "A49578-", - "A49579-", - "A49580-", - "T49581-", - "A49582-", - "T49583-", - "T49584-", - "A49585-", - "T49586-", - "T49587-", - "T49588-", - "A49589-", - "G49590-", - "A49591-", - "C49592-", - "G49593-", - "G49594-", - "A49595-", - "C49596-", - "A49597-", - "A49598-", - "T49599-", - "T49600-", - "G49601-", - "G49602-", - "C49603-", - "T49604-", - "C49605-", - "G49606-", - "T49607-", - "C49608-", - "T49609-", - "A49610-", - "G49611-", - "G49612-", - "T49613-", - "C49614-", - "T49615-", - "T49616-", - "G49617-", - "T49618-", - "G49619-", - "T49620-", - "T49621-", - "A49622-", - "G49623-", - "A49624-", - "T49625-", - "G49626-", - "A49627-", - "T49628-", - "T49629-", - "A49630-", - "T49631-", - "A49632-", - "A49633-", - "A49634-", - "G49635-", - "G49636-", - "A49637-", - "G49638-", - "A49639-", - "C49640-", - "T49641-", - "T49642-", - "A49643-", - "T49644-", - "T49645-", - "A49646-", - "G49647-", - "T49648-", - "T49649-", - "A49650-", - "A49651-", - "A49652-", - "A49653-", - "T49654-", - "G49655-", - "A49656-", - "T49657-", - "A49658-", - "A49659-", - "A49660-", - "C49661-", - "C49662-", - "A49663-", - "T49664-", - "C49665-", - "T49666-", - "C49667-", - "A49668-", - "A49669-", - "A49670-", - "T49671-", - "C49672-", - "T49673-", - "G49674-", - "T49675-", - "G49676-", - "G49677-", - "A49678-", - "G49680-", - "A49681-", - "T49682-", - "G49683-", - "T49684-", - "A49685-", - "T49686-", - "C49687-", - "C49688-", - "G49689-", - "C49690-", - "A49691-", - "T49692-", - "T49693-", - "C49694-", - "G49695-", - "T49696-", - "T49697-", - "A49698-", - "G49699-", - "A49700-", - "T49701-", - "T49702-", - "T49703-", - "T49704-", - "C49705-", - "T49706-", - "C49708-", - "A49709-", - "T62643-", - "G62644-", - "G62645-", - "A62646-", - "C62647-", - "T62648-", - "C62649-", - "G62650-", - "C62651-", - "G62652-", - "T62653-", - "T62654-", - "T62655-", - "A62656-", - "G62657-", - "A62658-", - "G62659-", - "G62660-", - "A62661-", - "G62662-", - "T62663-", - "G62664-", - "A62665-", - "A62666-", - "C62667-", - "G62668-", - "T62669-", - "C62670-", - "C67724T", - "T133095-", - "T133096-", - "T133097-", - "T133098-", - "T133099-", - "T178576-", - "A178577-", - "C178578-", - "A178579-", - "G178580-", - "T178581-", - "A178582-", - "A178583-", - "A178584-", - "T178585-", - "A178586-", - "G178587-", - "C178588-", - "A178589-", - "T178590-", - "A178591-", - "G178592-", - "A178593-", - "T178594-", - "A178595-", - "T178596-", - "G178597-", - "G178598-", - "A178599-", - "G178600-", - "G178601-", - "A178602-", - "G178603-", - "G178604-", - "A178605-", - "T178606-", - "A178607-", - "C178608-", - "A178609-", - "A178610-", - "A178611-", - "T178612-", - "A178613-", - "T178614-", - "T178615-", - "T178616-", - "C178617-", - "A178618-", - "A178619-", - "A178620-", - "T178621-", - "A178622-", - "A178623-", - "A178624-", - "G178625-", - "T178626-", - "T178627-", - "A178628-", - "T178629-", - "G178630-", - "A178631-", - "G178632-", - "A178633-", - "T178634-", - "A178635-", - "C178636-", - "G178637-", - "C178638-", - "G178639-", - "C178640-", - "T178641-", - "G178642-", - "T178643-", - "C178644-", - "A178645-", - "A178646-", - "T178647-", - "A178648-", - "A178649-", - "T178650-", - "A178651-", - "T178652-", - "A178653-", - "T178654-", - "G178655-", - "G178656-", - "A178657-", - "A178658-", - "G178659-", - "A178660-", - "C178661-", - "A178662-", - "T178663-", - "T178664-", - "A178665-", - "C178666-", - "C178667-", - "T178668-", - "A178669-", - "A178670-", - "C178671-", - "T178672-", - "T178673-", - "C178674-", - "T178675-", - "G178676-", - "A178677-", - "A178678-", - "C178679-", - "T178680-", - "G178681-", - "G178682-", - "A178683-", - "A178684-", - "C178685-", - "T178686-", - "A178687-", - "T178688-", - "A178689-", - "A178690-", - "A178691-", - "T178692-", - "C178693-", - "C178694-", - "A178695-", - "G178696-", - "G178697-", - "C178698-", - "T178699-", - "C178700-", - "T178701-", - "C178702-", - "G178703-", - "C178704-", - "A178705-", - "T178706-", - "A178707-", - "A178708-", - "A178709-", - "G178710-", - "A178711-", - "T178712-", - "G178713-", - "A178714-", - "A178715-", - "T178716-", - "A178717-", - "T178718-", - "A178719-", - "T178720-", - "A178721-", - "T178722-", - "G178723-", - "T178724-", - "T178725-", - "G178726-", - "T178727-", - "A178728-", - "T178729-", - "G178730-", - "C178731-", - "G178732-", - "A178733-", - "C178734-", - "A178735-", - "T178736-", - "C178737-", - "A178738-", - "A178739-", - "A178740-", - "G178741-", - "A178742-", - "T178743-", - "G178744-", - "A178745-", - "A178746-", - "A178747-", - "A178748-", - "A178749-", - "A178750-", - "T178751-", - "G178752-", - "T178753-", - "T178754-", - "A178755-", - "A178756-", - "G178757-", - "A178758-", - "C178759-", - "T178760-", - "T178761-", - "A178762-", - "T178763-", - "A178764-", - "T178765-", - "A178766-", - "T178767-", - "T178768-", - "T178769-", - "A178770-", - "G178771-", - "A178772-", - "T178773-", - "A178774-", - "T178775-", - "A178776-", - "A178777-", - "C178778-", - "A178779-", - "C178780-", - "G178781-", - "A178782-", - "A178783-", - "T178784-", - "A178785-", - "T178786-", - "G178787-", - "T178788-", - "A178789-", - "T178790-", - "G178791-", - "A178792-", - "C178793-", - "G178794-", - "G178795-", - "A178796-", - "T178797-", - "G178798-", - "G178799-", - "G178800-", - "A178801-", - "A178802-", - "T178803-", - "T178804-", - "G178805-", - "G178806-", - "T178807-", - "A178808-", - "A178809-", - "C178810-", - "G178811-", - "A178812-", - "T178813-", - "G178814-", - "A178815-", - "C178816-", - "A178817-", - "G178818-", - "A178819-", - "A178820-", - "A178821-", - "G178822-", - "C178823-", - "A178824-", - "G178825-", - "A178826-", - "T178827-", - "T178828-", - "G178829-", - "T178830-", - "C178831-", - "A178832-", - "G178833-", - "C178834-", - "T178835-", - "C178836-", - "T178837-", - "G178838-", - "C178839-", - "A178840-", - "T178841-", - "A178842-", - "C178843-", - "T178844-", - "A178845-", - "T178846-", - "T178847-", - "C178848-", - "T178849-", - "T178850-", - "C178851-", - "A178852-", - "T178853-", - "G178854-", - "A178855-", - "C178856-", - "A178857-", - "A178858-", - "T178859-", - "A178860-", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-", - "G178879-", - "T178880-", - "T178881-", - "A178882-", - "T178883-", - "G178884-", - "A178885-", - "A178886-", - "G178887-", - "C178888-", - "G178889-", - "T178890-", - "A178891-", - "T178892-", - "A178893-", - "T178894-", - "G178895-", - "T178896-", - "T178897-", - "A178898-", - "C178899-", - "A178900-", - "A178901-", - "G178902-", - "A178903-", - "T178904-", - "A178905-", - "C178906-", - "A178907-", - "T178908-", - "T178909-", - "T178910-", - "A178911-", - "A178912-", - "T178913-", - "G178914-", - "T178915-", - "G178916-" - ], - "OPG060": [ - "G97R" - ], - "OPG068": [ - "M1-", - "D2-", - "F3-", - "I4-", - "R5-", - "R6-", - "K7-", - "Y8-", - "L9X", - "N30X", - "K40-", - "Y41-", - "L42-", - "V43X", - "L56X", - "F61X", - "F62-", - "V63-", - "F64-", - "K72X", - "V73-", - "Y74-", - "E75-", - "A76-", - "V77-", - "L78X", - "E124X", - "Y125-", - "M126-", - "D127-", - "E128-", - "L129-", - "G130-", - "E131-", - "L132-", - "I133-", - "G134-", - "V135-", - "N136-", - "Y137-", - "D138-", - "L139-", - "V140X", - "P150-", - "I151-", - "K152-", - "D153-", - "M154-", - "E155-", - "I156-", - "I157-", - "F158-", - "K187X", - "D188-", - "T189-", - "G190-", - "I191-", - "E192-", - "F193-", - "A194-", - "D195-", - "N196-", - "D197V", - "D200Y", - "T208-", - "G209-", - "R210-", - "I211-", - "V212-", - "H213-", - "S214-", - "N215-", - "L216-", - "T217-", - "E218-", - "T219-", - "F220-", - "R221-", - "D222-", - "Y223-", - "I224-", - "F225-", - "P226X", - "N237-", - "E238-", - "S239-", - "I240X", - "Y256X", - "D257-", - "K258-", - "I259-", - "L260-", - "S261-", - "Y262-", - "I263-", - "Y264-", - "S265-", - "E266-", - "I267-", - "K268-", - "Q269-", - "G270-", - "R271-", - "V272-", - "N273-", - "K274-", - "N275-", - "M276-", - "L277-", - "K278-", - "L279X", - "F319X", - "I320-", - "S321-", - "F322-", - "Y323-", - "K324-", - "A325-", - "N326-", - "F327-", - "I328-", - "N329-", - "G330-", - "N331-", - "T332-", - "F333-", - "I334-", - "S335-", - "D336-", - "R337-", - "T338-", - "F339-", - "N340-", - "D341-", - "D342-", - "L343-", - "F344-", - "R345-", - "V346-", - "V347-", - "V348-", - "Q349-", - "I350-", - "D351-", - "P352-", - "E353-", - "Y354-", - "F355-", - "D356-", - "N357-", - "E358-", - "R359-", - "I360-", - "M361-", - "S362-", - "L363-", - "F364-", - "Y365-", - "T366-", - "S367-", - "A368-", - "A369-", - "D370-", - "I371-", - "K372-", - "R373-", - "F374-", - "D375-", - "E376-", - "L377-", - "D378-", - "I379-", - "N380-", - "N381-", - "S382-", - "Y383-", - "I384-", - "S385-", - "N386X", - "M399X", - "D400-", - "D401-", - "M402-", - "K403-", - "K404X", - "L425-", - "H426-", - "E427-", - "S428-", - "D429-", - "P430-", - "M431-", - "V432-", - "I433-", - "E434-", - "N435-", - "G436-", - "I437-", - "L438-", - "K439-", - "K440-", - "L441-", - "S442-", - "S443-", - "I444-", - "K445-", - "S446-", - "K447-", - "S448-", - "R449-", - "R450-", - "L451-", - "N452-", - "L453-", - "F454-", - "S455-", - "K456-", - "N457-", - "I458-", - "L459-", - "K460-", - "Y461-", - "Y462-", - "L463-", - "D464-", - "G465-", - "Q466-", - "L467-", - "A468-", - "R469-", - "L470-", - "G471-", - "L472-", - "V473-", - "L474-", - "D475-", - "D476-", - "Y477-", - "K478-", - "G479-", - "D480-", - "L481-", - "L482-", - "V483-", - "K484-", - "M485-", - "I486-", - "N487-", - "H488-", - "L489-", - "K490-", - "S491-", - "V492-", - "X493-", - "D494-", - "V495-", - "S496-", - "A497-", - "F498-", - "V499-", - "R500-", - "F501-", - "S502-", - "X503-" - ], - "OPG082": [ - "K261X", - "T262-", - "F263-", - "T264-", - "P265-", - "L266-", - "N267-", - "A268-", - "S269-", - "P270-" - ], - "OPG085": [ - "E270K" - ] - }, - "labels": { - "aa": "OPG060: G97R; OPG068: M1-, D2-, F3-, I4-, R5-, R6-, K7-, Y8-, L9X, N30X, K40-, Y41-, L42-, V43X, L56X, F61X, F62-, V63-, F64-, K72X, V73-, Y74-, E75-, A76-, V77-, L78X, E124X, Y125-, M126-, D127-, E128-, L129-, G130-, E131-, L132-, I133-, G134-, V135-, N136-, Y137-, D138-, L139-, V140X, P150-, I151-, K152-, D153-, M154-, E155-, I156-, I157-, F158-, K187X, D188-, T189-, G190-, I191-, E192-, F193-, A194-, D195-, N196-, D197V, D200Y, T208-, G209-, R210-, I211-, V212-, H213-, S214-, N215-, L216-, T217-, E218-, T219-, F220-, R221-, D222-, Y223-, I224-, F225-, P226X, N237-, E238-, S239-, I240X, Y256X, D257-, K258-, I259-, L260-, S261-, Y262-, I263-, Y264-, S265-, E266-, I267-, K268-, Q269-, G270-, R271-, V272-, N273-, K274-, N275-, M276-, L277-, K278-, L279X, F319X, I320-, S321-, F322-, Y323-, K324-, A325-, N326-, F327-, I328-, N329-, G330-, N331-, T332-, F333-, I334-, S335-, D336-, R337-, T338-, F339-, N340-, D341-, D342-, L343-, F344-, R345-, V346-, V347-, V348-, Q349-, I350-, D351-, P352-, E353-, Y354-, F355-, D356-, N357-, E358-, R359-, I360-, M361-, S362-, L363-, F364-, Y365-, T366-, S367-, A368-, A369-, D370-, I371-, K372-, R373-, F374-, D375-, E376-, L377-, D378-, I379-, N380-, N381-, S382-, Y383-, I384-, S385-, N386X, M399X, D400-, D401-, M402-, K403-, K404X, L425-, H426-, E427-, S428-, D429-, P430-, M431-, V432-, I433-, E434-, N435-, G436-, I437-, L438-, K439-, K440-, L441-, S442-, S443-, I444-, K445-, S446-, K447-, S448-, R449-, R450-, L451-, N452-, L453-, F454-, S455-, K456-, N457-, I458-, L459-, K460-, Y461-, Y462-, L463-, D464-, G465-, Q466-, L467-, A468-, R469-, L470-, G471-, L472-, V473-, L474-, D475-, D476-, Y477-, K478-, G479-, D480-, L481-, L482-, V483-, K484-, M485-, I486-, N487-, H488-, L489-, K490-, S491-, V492-, X493-, D494-, V495-, S496-, A497-, F498-, V499-, R500-, F501-, S502-, X503-; OPG082: K261X, T262-, F263-, T264-, P265-, L266-, N267-, A268-, S269-, P270-; OPG085: E270K" - } - } - }, - { - "name": "NODE_0000112", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A62106-", - "T62107-", - "A62108-", - "G62109-", - "A62110-", - "T62111-", - "A62112-", - "A62113-", - "A62114-", - "G62115-", - "A62116-", - "G62117-", - "T62118-", - "C62119-", - "C62120-", - "T62121-", - "A62122-", - "T62123-", - "A62124-", - "T62125-", - "A62126-", - "T62127-", - "T62128-", - "T62129-", - "G62130-", - "A62131-", - "A62132-", - "A62133-", - "A62134-", - "T62135-", - "C62136-", - "G62137-", - "T62138-", - "T62139-", - "A62140-", - "C62141-", - "G62142-", - "G62143-", - "T62144-", - "T62145-", - "C62146-", - "G62147-", - "A62148-", - "T62164-", - "G62165-", - "C62166-", - "A62167-", - "T62168-", - "T62169-", - "G62170-", - "T62171-", - "G62172-", - "A62173-", - "A62174-", - "T62175-", - "A62176-", - "T62177-", - "A62178-", - "T62179-", - "C62180-", - "A62181-", - "T62182-", - "T62183-", - "A62184-", - "G62185-", - "G62186-", - "A62187-", - "T62188-", - "T62189-", - "T62190-", - "A62191-", - "A62192-", - "C62193-", - "T62194-", - "C62195-", - "C62196-", - "T62197-", - "T62198-", - "G62199-", - "A62200-", - "C62201-", - "T62202-", - "A62203-", - "T62204-", - "C62205-", - "A62206-", - "T62207-", - "G62208-", - "G62209-", - "C62210-", - "G62211-", - "G62212-", - "T62213-", - "G62214-", - "C62215-", - "C62216-", - "A62217-", - "G62218-", - "A62219-", - "A62220-", - "A62221-", - "T62222-", - "T62223-", - "A62224-", - "C62225-", - "C62226-", - "A62227-", - "T62228-", - "C62229-", - "A62230-", - "A62231-", - "A62232-", - "A62233-", - "G62234-", - "C62235-", - "A62236-", - "T62237-", - "T62238-", - "A62239-", - "A62240-", - "T62241-", - "A62242-", - "C62243-", - "A62244-", - "G62245-", - "T62246-", - "T62247-", - "A62248-", - "T62249-", - "G62250-", - "C62251-", - "A62252-", - "G62253-", - "A62254-", - "T62255-", - "C62256-", - "G62257-", - "A62263-", - "G62264-", - "A62265-", - "A62266-", - "C62267-", - "G62268-", - "G62269-", - "T62270-", - "T62271-", - "A62272-", - "T62273-", - "A62274-", - "G62275-", - "C62276-", - "A62277-", - "T62278-", - "C62279-", - "C62280-", - "A62281-", - "C62282-", - "C62283-", - "A62284-", - "T62285-", - "T62286-", - "T62287-", - "A62288-", - "T62289-", - "A62290-", - "T62291-", - "C62292-", - "T62293-", - "A62294-", - "A62295-", - "A62296-", - "A62297-", - "A62298-", - "T62299-", - "T62300-", - "A62301-", - "G62302-", - "A62303-", - "T62304-", - "A62310-", - "A62311-", - "T62312-", - "A62313-", - "T62314-", - "G62315-", - "T62316-", - "G62317-", - "A62318-", - "C62319-", - "A62320-", - "A62321-", - "C62322-", - "G62323-", - "T62324-", - "A62347-", - "C62348-", - "G62349-", - "A62350-", - "A62351-", - "A62352-", - "C62353-", - "A62354-", - "A62355-", - "T62356-", - "T62358-", - "T62359-", - "T62360-", - "T62362-", - "T62363-", - "A62364-", - "A62366-", - "T62367-", - "A62368-", - "T62369-", - "T62370-", - "T62371-", - "T62377-", - "T62378-", - "A62379-", - "T62380-", - "T62381-", - "A62382-", - "G62383-", - "T62384-", - "A62385-", - "A62386-", - "C62387-", - "C62388-", - "G62389-", - "A62390-", - "C62391-", - "T62392-", - "T62393-", - "A62394-", - "A62395-", - "T62396-", - "A62397-", - "G62398-", - "T62399-", - "A62400-", - "G62401-", - "G62402-", - "A62403-", - "A62415-", - "G62416-", - "A62417-", - "C62418-", - "T62419-", - "T62420-", - "G62421-", - "A62422-", - "T62423-", - "T62424-", - "A62425-", - "T62426-", - "T62427-", - "C62428-", - "T62429-", - "A62430-", - "T62431-", - "G62439-", - "A62440-", - "T62441-", - "A62442-", - "C62443-", - "C62444-", - "C62445-", - "T62446-", - "T62447-", - "C62448-", - "C62449-", - "A62450-", - "A62451-", - "A62452-", - "T62453-", - "A62454-", - "A62455-", - "T62456-", - "G62457-", - "T62458-", - "T62459-", - "C62460-", - "T62461-", - "C62462-", - "T62463-", - "T62464-", - "T62465-", - "G62466-", - "A62467-", - "T62468-", - "A62469-", - "A62470-", - "A62471-", - "A62472-", - "G62473-", - "T62474-", - "T62475-", - "C62476-", - "C62477-", - "A62478-", - "G62479-", - "A62480-", - "A62481-", - "A62482-", - "A62483-", - "T62484-", - "G62485-", - "T62486-", - "A62487-", - "G62488-", - "A62489-", - "A62490-", - "T62491-", - "T62492-", - "T62493-", - "T62494-", - "T62495-", - "T62496-", - "A62497-", - "A62498-", - "A62499-", - "A62500-", - "A62501-", - "G62502-", - "T62503-", - "T62504-", - "A62505-", - "T62506-", - "C62507-", - "T62508-", - "T62509-", - "T62510-", - "T62511-", - "G62512-", - "C62513-", - "T62514-", - "A62515-", - "T62516-", - "T62517-", - "A62518-", - "C62519-", - "T62520-", - "A62521-", - "A62522-", - "T62523-", - "A62524-", - "T62525-", - "C62526-", - "G62527-", - "T62528-", - "G62529-", - "G62530-", - "T62531-", - "G62534-", - "A62535-", - "C62536-", - "G62537-", - "C62538-", - "T62539-", - "T62540-", - "A62541-", - "T62542-", - "T62543-", - "A62544-", - "T62545-", - "T62546-", - "A62547-", - "A62548-", - "T62549-", - "A62550-", - "T62551-", - "T62555-", - "G62556-", - "A62557-", - "T62558-", - "G62559-", - "A62560-", - "A62561-", - "A62562-", - "T62563-", - "C62564-", - "C62565-", - "A62566-", - "C62567-", - "A62568-", - "C62569-", - "C62570-", - "A62579-", - "T62580-", - "A62581-", - "T62582-", - "C62583-", - "G62584-", - "C62585-", - "T62586-", - "T62587-", - "T62588-", - "T62589-", - "A62590-", - "T62591-", - "T62592-", - "T62593-", - "C62594-", - "C62595-", - "A62596-", - "C62597-", - "A62598-", - "T62600-", - "A62601-", - "G62602-", - "A62603-", - "T62604-", - "G62605-", - "G62606-", - "T62607-", - "A62608-", - "A62609-", - "A62610-", - "T62611-", - "C62612-", - "C62613-", - "A62614-", - "A62615-", - "T62616-", - "A62617-", - "G62618-", - "T62619-", - "G62620-", - "A62621-", - "A62622-", - "C62628-", - "T62691-", - "T62692-", - "C62693-", - "G62694-", - "T62695-", - "C62696-", - "A62697-", - "A62698-", - "A62699-", - "T62700-", - "G62701-", - "A62702-", - "A62703-", - "T62704-", - "A62705-", - "A62706-", - "A62707-", - "C62708-", - "A62709-", - "A62710-", - "T62711-", - "T62712-", - "T62713-", - "C62714-", - "A62715-", - "C62716-", - "A62717-", - "A62718-", - "A62719-", - "T62720-", - "G62721-", - "G62722-", - "A62723-", - "T62724-", - "G62725-", - "T62726-", - "T62727-", - "A62728-", - "A62729-", - "T62730-", - "G62731-", - "T62732-", - "A62733-", - "T62734-", - "T62735-", - "A62736-", - "G62737-", - "T62738-", - "A62739-", - "G62740-", - "G62741-", - "A62742-", - "A62743-", - "A62744-", - "T62745-", - "T62746-", - "T62747-", - "T62748-", - "T62749-", - "T62750-", - "G62751-", - "A62752-", - "C62753-", - "G62754-", - "C62755-", - "T62756-", - "A62757-", - "A62806-", - "A62807-", - "C62808-", - "A62809-", - "T62810-", - "G62811-", - "T62812-", - "T62813-", - "A62814-", - "A62815-", - "T62816-", - "T62817-", - "A62822-", - "T62823-", - "A62824-", - "C62825-", - "C62826-", - "A62827-", - "A62828-", - "C62829-", - "G62830-", - "G62831-", - "T62832-", - "T62833-", - "T62834-", - "T62835-", - "A62836-", - "A62837-", - "T62838-", - "A62839-", - "T62840-", - "T62841-", - "T62842-", - "C62843-", - "G62844-", - "A62845-", - "T62846-", - "G62847-", - "A62848-", - "T62849-", - "A62850-", - "T62851-", - "A62852-", - "C62853-", - "G62870-", - "A62871-", - "C62872-", - "T62873-", - "T62874-", - "A62875-", - "T62876-", - "A62877-", - "T62878-", - "A62879-", - "G62880-", - "C62881-", - "T62882-", - "T62883-", - "A62884-", - "T62885-", - "T62886-", - "C62887-", - "C62888-", - "A62889-", - "C62890-", - "A62891-", - "A62913-", - "A62914-", - "A62915-", - "A62916-", - "A62917-", - "A62918-", - "C62919-", - "A62920-", - "A62921-", - "A62922-", - "A62923-", - "T62924-", - "A62925-", - "A62926-", - "C62927-", - "T62928-", - "A62929-", - "G62930-", - "A62932-", - "T62933-", - "A62934-", - "A62935-", - "A62936-", - "A62937-", - "T62938-", - "C62939-", - "T62940-", - "G62941-", - "T62942-", - "A62948-", - "T62949-", - "G62950-", - "G62951-", - "G62952-", - "A62953-", - "A62954-", - "A62955-", - "A62956-", - "A62957-", - "C62958-", - "G62959-", - "A62960-", - "A62961-", - "A62962-", - "T62963-", - "T62964-", - "A62969-", - "T62970-", - "A62971-", - "T62972-", - "A62973-", - "G62974-", - "G62975-", - "T62976-", - "A62977-", - "T62978-", - "A62979-", - "T62993-", - "G62994-", - "A62995-", - "A62996-", - "C62997-", - "G62998-", - "T62999-", - "A63000-", - "T63001-", - "T63002-", - "A63003-", - "A63004-", - "T63005-", - "A63006-", - "C63007-", - "T63008-", - "T63009-", - "A63010-", - "A63011-", - "T63012-", - "T63013-", - "C63014-", - "T63015-", - "T63016-", - "T63017-", - "T63018-", - "T63019-", - "C63020-", - "A63021-", - "G63022-", - "C63032-", - "C63033-", - "G63034-", - "A63035-", - "T63036-", - "A63037-", - "G63038-", - "G63039-", - "T63040-", - "T63041-", - "T63043-", - "T63044-", - "G63045-", - "A63046-", - "C63047-", - "A63048-", - "T63049-", - "T63050-", - "G63051-", - "T63052-", - "A63053-", - "T63054-", - "G63055-", - "G63056-", - "T63057-", - "T63058-", - "T63059-", - "T63060-", - "A63061-", - "A63062-", - "A63063-", - "T63064-", - "A63065-", - "T63066-", - "T63067-", - "C63068-", - "T63069-", - "A63070-", - "T63071-", - "A63072-", - "A63073-", - "C63074-", - "A63087-", - "G63088-", - "A63089-", - "T63090-", - "A63091-", - "T63092-", - "T63093-", - "A63094-", - "A63095-", - "T63096-", - "G63097-", - "A63098-", - "C63099-", - "G63100-", - "A63101-", - "G63105-", - "A63106-", - "A63107-", - "A63108-", - "A63109-", - "T63110-", - "T63111-", - "A63112-", - "T63113-", - "T63114-", - "T63115-", - "T63116-", - "T63117-", - "A63118-", - "T63119-", - "C63120-", - "A63121-", - "C63122-", - "C63123-", - "A63124-", - "C63125-", - "G63126-", - "T63127-", - "G63128-", - "T63129-", - "G63130-", - "T63131-", - "T63132-", - "T63133-", - "C63134-", - "A63135-", - "G63136-", - "G63137-", - "A63138-", - "T63139-", - "C63140-", - "A63141-", - "T63142-", - "G63154-", - "T63155-", - "T63156-", - "A63157-", - "A63158-", - "C63159-", - "C63160-", - "A63161-", - "A63162-", - "C63163-", - "C63164-", - "G63165-", - "A63166-", - "A63174-", - "A63175-", - "A63176-", - "A63177-", - "T63178-", - "A63179-", - "A63180-", - "A63181-", - "T63182-", - "A63183-", - "T63184-", - "C63185-", - "A63186-", - "T63187-", - "T63188-", - "A63189-", - "A63190-", - "T63191-", - "A63192-", - "T63193-", - "A63194-", - "T63195-", - "G63196-", - "C63197-", - "T63198-", - "C63199-", - "T63200-", - "A63201-", - "G63202-", - "A63203-", - "T63204-", - "A63205-", - "T63206-", - "T63207-", - "A63208-", - "G63209-", - "T63210-", - "A63211-", - "T63212-", - "T63213-", - "T63214-", - "T63215-", - "T63216-", - "A63217-", - "T63218-", - "T63219-", - "A63220-", - "A63221-", - "T63222-", - "C63223-", - "C63224-", - "T63225-", - "T63226-", - "T63227-", - "G63228-", - "A63229-", - "T63230-", - "T63231-", - "A63232-", - "T63233-", - "C63234-", - "A63235-", - "T63236-", - "C63237-", - "T63238-", - "C63248-", - "G63249-", - "A63250-", - "A63251-", - "T63252-", - "G63253-", - "A63254-", - "T63286-", - "C63287-", - "C63288-", - "G63289-", - "G63290-", - "A63291-", - "G63292-", - "T63293-", - "A63294-", - "T63295-", - "T63296-", - "A63297-", - "A63298-", - "T63299-", - "G63300-", - "G63301-", - "G63302-", - "T63303-", - "T63304-", - "T63305-", - "A63306-", - "G63307-", - "T63308-", - "A63309-", - "A63310-", - "C63316-", - "C63317-", - "A63318-", - "T63319-", - "C63320-", - "G63321-", - "T63322-", - "T63323-", - "G63324-", - "C63325-", - "A63326-", - "A63327-", - "A63332-", - "A63333-", - "A63334-", - "A63335-", - "G63336-", - "T63337-", - "T63338-", - "G63339-", - "T63340-", - "C63341-", - "C63342-", - "A63343-", - "A63344-", - "G63345-", - "T63346-", - "A63349-", - "A63350-", - "G63351-", - "G63352-", - "A63353-", - "T63354-", - "A63355-", - "T63356-", - "T63357-", - "A63358-", - "T63359-", - "G63360-", - "C63361-", - "A63362-", - "T63363-", - "T63364-", - "A63372-", - "G63373-", - "A63374-", - "T63375-", - "A63376-", - "T63377-", - "C63378-", - "A63379-", - "C63380-", - "C63381-", - "T63382-", - "C63383-", - "A63384-", - "G63457-", - "T63458-", - "C63459-", - "T63460-", - "A63461-", - "C63462-", - "T63463-", - "A63464-", - "T63465-", - "T63466-", - "C63467-", - "T63468-", - "A63469-", - "T63470-", - "T63471-", - "T63472-", - "A63473-", - "A63474-", - "T63475-", - "T63476-", - "T63477-", - "T63478-", - "G63479-", - "T63480-", - "A63481-", - "G63482-", - "T63483-", - "T63484-", - "A63485-", - "A63486-", - "T63487-", - "T63488-", - "T63489-", - "A63490-", - "T63491-", - "C63492-", - "C89166T", - "-178558T", - "-178559G", - "-178560A", - "-178561T", - "-178562T", - "-178563A", - "-178564T", - "-178565A", - "-178566C", - "-178567A", - "-178568T", - "-178569C", - "-178570G", - "-178571G", - "-178572T", - "-178573A", - "-178574C", - "-178575A", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-" - ], - "OPG081": [ - "M1-", - "V2-", - "D3-", - "A4-", - "I5-", - "T6-", - "V7-", - "X8-", - "X10-", - "I11-", - "C12-", - "I13-", - "T14-", - "V15-", - "L16-", - "M17-", - "L18-", - "L19-", - "M20-", - "V21-", - "I22-", - "S23-", - "G24-", - "T25-", - "A26-", - "M27-", - "I28-", - "V29-", - "K30-", - "E31-", - "L32-", - "N33-", - "P34-", - "N35-", - "D36-", - "I37-", - "F38-", - "T39-", - "M40-", - "Q41X", - "N46X", - "R47-", - "T48-", - "V49-", - "T50-", - "I51-", - "F52-", - "K53-", - "Y54-", - "I55-", - "G56-", - "L57-", - "F58-", - "I59-", - "Y60-" - ], - "OPG082": [ - "X23-", - "E24-", - "V25-", - "I26-", - "S27-", - "X30-", - "C31-", - "I32-", - "I33-", - "S34-", - "X35-", - "X36-", - "L37-", - "D38-", - "N39-", - "F40-", - "X41-", - "X42-", - "C43-", - "N44-", - "D45-", - "X46-", - "X48-", - "T49-", - "K50-", - "P51-", - "I52-", - "N53-", - "T54-", - "P55-", - "X56-", - "S67-", - "F68-", - "X69-", - "X72-", - "M73-", - "I74-", - "I75-", - "K76-", - "G77-", - "L78-", - "I79-", - "K80-", - "I81-", - "L82-", - "I83-", - "S84-", - "R85-", - "A86-", - "Y87-", - "I88-", - "N89-", - "D90-", - "I91-", - "Y92-", - "F93-", - "X96-", - "G97-", - "W98-", - "L99-", - "X100-", - "X104-", - "D105-", - "P106-", - "E107-", - "T108-", - "H109-", - "V110-", - "V111-", - "I112-", - "K113-", - "I114-", - "I115-", - "F116-", - "S118-", - "S119-", - "L120-", - "I121-", - "S122-", - "V127-", - "I128-", - "E129-", - "Y130-", - "L131-", - "K132-", - "P133-", - "Y134-", - "N135-", - "V136-", - "X137-", - "N138-", - "L139-", - "S140-", - "X141-", - "X144-", - "E145-", - "K146-", - "E147-", - "L148-", - "S149-", - "I150-", - "N151-", - "T152-", - "F153-", - "X154-", - "X158-", - "I159-", - "P160-", - "I161-", - "X162-", - "X163-", - "I164-", - "S165-", - "F166-", - "F167-", - "P168-", - "X169-", - "T171-", - "D172-", - "F173-", - "X174-", - "L175-", - "V176-", - "I177-", - "L178-", - "F179-", - "F180-", - "C188-", - "G189-", - "I190-", - "S191-", - "Y192-", - "I193-", - "S194-", - "X195-", - "X200-", - "Y201-", - "I202-", - "I203-", - "E204-", - "I205-", - "L206-", - "K207-", - "P208-", - "L209-", - "V210-", - "X211-", - "X212-", - "I213-", - "N214-", - "M215-", - "X216-", - "X232-", - "S233-", - "V234-", - "K235-", - "K236-", - "F237-", - "P238-", - "T239-", - "N240-", - "T241-", - "L242-", - "T243-", - "S244-", - "I245-", - "C246-", - "E247-", - "I248-", - "V249-", - "Y250-", - "S251-", - "F252-", - "D253-", - "E254-", - "K275X", - "X277-", - "S278-", - "L279-", - "L280-", - "D281-", - "L282-", - "P283-", - "S284-", - "X285-", - "V286-", - "E287-", - "I288-", - "K289-", - "A290-", - "I291-", - "X292-", - "G295-", - "V296-", - "D297-", - "F298-", - "I299-", - "X300-", - "X301-", - "I302-", - "N303-", - "N304-", - "K305-", - "R306-", - "X307-", - "T308-", - "T309-", - "I310-", - "L311-", - "V312-", - "I313-", - "A314-", - "K315-", - "D316-", - "N317-", - "F318-", - "L319-", - "K320-", - "N321-", - "S322-", - "T323-", - "F324-", - "S325-", - "G326-", - "T327-", - "F328-", - "I329-", - "K330-", - "E331-", - "N332-", - "I333-", - "I334-", - "W335-", - "K336-", - "G337-", - "I338-", - "X341-", - "R342-", - "I343-", - "I344-", - "K345-", - "S346-", - "X350-", - "P351-", - "T352-", - "I353-", - "K354-", - "S355-", - "V356-", - "T357-", - "N358-", - "X359-", - "X361-", - "I362-", - "C363X", - "K364X", - "K365-", - "H366X", - "C367-", - "F368-", - "X369-", - "T377-", - "L378-", - "S379-", - "H380-", - "I381-", - "X383-" - ], - "OPG083": [ - "D409-", - "K410-", - "L411-", - "T412-", - "T413-", - "K414-", - "L415-", - "N416-", - "R417-", - "I418-", - "V419-", - "D420-" - ] - }, - "labels": { - "aa": "OPG081: M1-, V2-, D3-, A4-, I5-, T6-, V7-, X8-, X10-, I11-, C12-, I13-, T14-, V15-, L16-, M17-, L18-, L19-, M20-, V21-, I22-, S23-, G24-, T25-, A26-, M27-, I28-, V29-, K30-, E31-, L32-, N33-, P34-, N35-, D36-, I37-, F38-, T39-, M40-, Q41X, N46X, R47-, T48-, V49-, T50-, I51-, F52-, K53-, Y54-, I55-, G56-, L57-, F58-, I59-, Y60-; OPG082: X23-, E24-, V25-, I26-, S27-, X30-, C31-, I32-, I33-, S34-, X35-, X36-, L37-, D38-, N39-, F40-, X41-, X42-, C43-, N44-, D45-, X46-, X48-, T49-, K50-, P51-, I52-, N53-, T54-, P55-, X56-, S67-, F68-, X69-, X72-, M73-, I74-, I75-, K76-, G77-, L78-, I79-, K80-, I81-, L82-, I83-, S84-, R85-, A86-, Y87-, I88-, N89-, D90-, I91-, Y92-, F93-, X96-, G97-, W98-, L99-, X100-, X104-, D105-, P106-, E107-, T108-, H109-, V110-, V111-, I112-, K113-, I114-, I115-, F116-, S118-, S119-, L120-, I121-, S122-, V127-, I128-, E129-, Y130-, L131-, K132-, P133-, Y134-, N135-, V136-, X137-, N138-, L139-, S140-, X141-, X144-, E145-, K146-, E147-, L148-, S149-, I150-, N151-, T152-, F153-, X154-, X158-, I159-, P160-, I161-, X162-, X163-, I164-, S165-, F166-, F167-, P168-, X169-, T171-, D172-, F173-, X174-, L175-, V176-, I177-, L178-, F179-, F180-, C188-, G189-, I190-, S191-, Y192-, I193-, S194-, X195-, X200-, Y201-, I202-, I203-, E204-, I205-, L206-, K207-, P208-, L209-, V210-, X211-, X212-, I213-, N214-, M215-, X216-, X232-, S233-, V234-, K235-, K236-, F237-, P238-, T239-, N240-, T241-, L242-, T243-, S244-, I245-, C246-, E247-, I248-, V249-, Y250-, S251-, F252-, D253-, E254-, K275X, X277-, S278-, L279-, L280-, D281-, L282-, P283-, S284-, X285-, V286-, E287-, I288-, K289-, A290-, I291-, X292-, G295-, V296-, D297-, F298-, I299-, X300-, X301-, I302-, N303-, N304-, K305-, R306-, X307-, T308-, T309-, I310-, L311-, V312-, I313-, A314-, K315-, D316-, N317-, F318-, L319-, K320-, N321-, S322-, T323-, F324-, S325-, G326-, T327-, F328-, I329-, K330-, E331-, N332-, I333-, I334-, W335-, K336-, G337-, I338-, X341-, R342-, I343-, I344-, K345-, S346-, X350-, P351-, T352-, I353-, K354-, S355-, V356-, T357-, N358-, X359-, X361-, I362-, C363X, K364X, K365-, H366X, C367-, F368-, X369-, T377-, L378-, S379-, H380-, I381-, X383-; OPG083: D409-, K410-, L411-, T412-, T413-, K414-, L415-, N416-, R417-, I418-, V419-, D420-" - } - }, - "children": [ - { - "name": "02112022_anal", - "node_attrs": { - "div": 558, - "author": { - "author": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K.", - "value": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "date": { - "value": "2022-11-02" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "02112022_anal" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ672570" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G62357-", - "C62361-", - "C62365-" - ], - "OPG082": [ - "X363-", - "X364-", - "X366-" - ] - }, - "labels": { - "aa": "OPG082: X363-, X364-, X366-" - } - } - }, - { - "name": "NODE_0000113", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C2621-", - "A47697-", - "T47698-", - "T47699-", - "A47700-", - "C47701-", - "G47702-", - "A47703-", - "G47704-", - "A47705-", - "C47706-", - "A47707-", - "T47708-", - "T47709-", - "G47710-", - "A47711-", - "A47712-", - "A47713-", - "C47714-", - "T47715-", - "A47716-", - "G47717-", - "G47718-", - "A47719-", - "T47720-", - "A47721-", - "T47722-", - "A47723-", - "T47724-", - "A47725-", - "A47726-", - "A47727-", - "A47728-", - "T47729-", - "T47730-", - "T47731-", - "A47732-", - "A47733-", - "G47734-", - "G47735-", - "G47736-", - "A47737-", - "A47738-", - "T47739-", - "G47740-", - "A47747-", - "C47748-", - "T47749-", - "C47751-", - "T47752-", - "A47753-", - "C47754-", - "T47755-", - "C47756-", - "T47757-", - "A47758-", - "G47759-", - "A47760-", - "A47761-", - "G47762-", - "A47763-", - "T47764-", - "A47765-", - "G47768-", - "C47769-", - "C47771-", - "T47774-", - "C47967-", - "C47968-", - "T47969-", - "G47970-", - "T47971-", - "T47972-", - "C47973-", - "G47974-", - "T47975-", - "A47976-", - "T47977-", - "G47978-", - "C47979-", - "C47980-", - "T47981-", - "G47982-", - "T47983-", - "G47984-", - "G47985-", - "C47986-", - "T47987-", - "A47988-", - "A47989-", - "G47990-", - "A47991-", - "T47992-", - "A47993-", - "C47994-", - "T47995-", - "G47996-", - "T47997-", - "G47998-", - "T47999-", - "A48000-", - "A48001-", - "A48002-", - "G48003-", - "A48004-", - "A48005-", - "A48006-", - "T48007-", - "G48008-", - "G48009-", - "T48010-", - "A48011-", - "-49679G", - "-49707A", - "-62356T", - "-62358T", - "-62359T", - "-62360T", - "-62362T", - "-62363T", - "-62364A", - "-62366A", - "-62367T", - "-62368A", - "-62369T", - "-62370T", - "-62371T", - "-62372T", - "-62373T", - "-62374T", - "-62375T", - "C151552T", - "C167451T", - "A178687-", - "T178688-", - "A178689-", - "A178690-", - "A178691-", - "T178692-", - "A178695-", - "T178699-", - "T178701-", - "A178824-", - "G178825-", - "A178826-", - "T178827-", - "T178828-", - "G178829-", - "T178830-", - "C178831-", - "A178832-", - "G178833-", - "C178834-", - "T178835-", - "C178836-", - "T178837-", - "G178838-", - "C178839-", - "A178840-", - "T178841-", - "G187391A" - ], - "OPG068": [ - "X493E", - "X503T", - "X568*" - ], - "OPG082": [ - "-360K", - "-361K", - "-362I", - "X363C", - "X364K", - "-365K" - ], - "OPG178": [ - "S15F" - ] - }, - "labels": { - "aa": "OPG068: X493E, X503T, X568*; OPG082: -360K, -361K, -362I, X363C, X364K, -365K; OPG178: S15F" - } - }, - "children": [ - { - "name": "02022023_anal", - "node_attrs": { - "div": 561, - "author": { - "author": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K.", - "value": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "date": { - "value": "2023-02-02" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "02022023_anal" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ672574" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-62106A", - "-62107T", - "-62108A", - "-62109G", - "-62110A", - "-62111T", - "-62112A", - "-62113A", - "-62114A", - "-62115G", - "-62116A", - "-62117G", - "-62118T", - "-62119C", - "-62120C", - "-62121T", - "-62122A", - "-62123T", - "-62124A", - "-62125T", - "-62126A", - "-62127T", - "-62128T", - "-62129T", - "-62130G", - "-62131A", - "-62132A", - "-62133A", - "-62134A", - "-62135T", - "-62136C", - "-62137G", - "-62138T", - "-62139T", - "-62140A", - "-62141C", - "-62142G", - "-62143G", - "-62144T", - "-62145T", - "-62146C", - "-62147G", - "-62148A", - "-62164T", - "-62165G", - "-62166C", - "-62167A", - "-62168T", - "-62169T", - "-62170G", - "-62171T", - "-62172G", - "-62173A", - "-62174A", - "-62175T", - "-62176A", - "-62177T", - "-62178A", - "-62179T", - "-62180C", - "-62181A", - "-62182T", - "-62183T", - "-62184A", - "-62185G", - "-62186G", - "-62187A", - "-62188T", - "-62189T", - "-62190T", - "-62191A", - "-62192A", - "-62193C", - "-62194T", - "-62195C", - "-62196C", - "-62197T", - "-62198T", - "-62199G", - "-62200A", - "-62201C", - "-62202T", - "-62203A", - "-62204T", - "-62205C", - "-62206A", - "-62207T", - "-62208G", - "-62209G", - "-62210C", - "-62211G", - "-62212G", - "-62213T", - "-62214G", - "-62215C", - "-62216C", - "-62217A", - "-62218G", - "-62219A", - "-62220A", - "-62221A", - "-62222T", - "-62223T", - "-62224A", - "-62225C", - "-62226C", - "-62227A", - "-62228T", - "-62229C", - "-62230A", - "-62231A", - "-62232A", - "-62233A", - "-62234G", - "-62235C", - "-62236A", - "-62237T", - "-62238T", - "-62239A", - "-62240A", - "-62241T", - "-62242A", - "-62243C", - "-62244A", - "-62245G", - "-62246T", - "-62247T", - "-62248A", - "-62249T", - "-62250G", - "-62251C", - "-62252A", - "-62253G", - "-62254A", - "-62255T", - "-62256C", - "-62257G", - "-62258C", - "-62259A", - "-62260G", - "-62261T", - "-62262T", - "-62263A", - "-62264G", - "-62265A", - "-62266A", - "-62267C", - "-62268G", - "-62269G", - "-62270T", - "-62271T", - "-62272A", - "-62273T", - "-62274A", - "-62275G", - "-62276C", - "-62277A", - "-62278T", - "-62279C", - "-62280C", - "-62281A", - "-62282C", - "-62283C", - "-62284A", - "-62285T", - "-62286T", - "-62287T", - "-62288A", - "-62289T", - "-62290A", - "-62291T", - "-62292C", - "-62293T", - "-62294A", - "-62295A", - "-62296A", - "-62297A", - "-62298A", - "-62299T", - "-62300T", - "-62301A", - "-62302G", - "-62303A", - "-62304T", - "-62305C", - "-62306A", - "-62307A", - "-62308A", - "-62309G", - "-62310A", - "-62311A", - "-62312T", - "-62313A", - "-62314T", - "-62315G", - "-62316T", - "-62317G", - "-62318A", - "-62319C", - "-62320A", - "-62321A", - "-62322C", - "-62323G", - "-62324T", - "-62325C", - "-62326C", - "-62327T", - "-62328A", - "-62329G", - "-62330T", - "-62331T", - "-62332G", - "-62333T", - "-62334A", - "-62335T", - "-62336A", - "-62337C", - "-62338T", - "-62339G", - "-62340A", - "-62341G", - "-62342A", - "-62343A", - "-62344T", - "-62345T", - "-62346G", - "-62347A", - "-62348C", - "-62349G", - "-62350A", - "-62351A", - "-62352A", - "-62353C", - "-62354A", - "-62355A", - "-62376C", - "-62377T", - "-62378T", - "-62379A", - "-62380T", - "-62381T", - "-62382A", - "-62383G", - "-62384T", - "-62385A", - "-62386A", - "-62387C", - "-62388C", - "-62389G", - "-62390A", - "-62391C", - "-62392T", - "-62393T", - "-62394A", - "-62395A", - "-62396T", - "-62397A", - "-62398G", - "-62399T", - "-62400A", - "-62401G", - "-62402G", - "-62403A", - "-62404A", - "-62405C", - "-62406T", - "-62407G", - "-62408G", - "-62409A", - "-62410A", - "-62411A", - "-62412A", - "-62413C", - "-62414T", - "-62415A", - "-62416G", - "-62417A", - "-62418C", - "-62419T", - "-62420T", - "-62421G", - "-62422A", - "-62423T", - "-62424T", - "-62425A", - "-62426T", - "-62427T", - "-62428C", - "-62429T", - "-62430A", - "-62431T", - "-62432A", - "-62433A", - "-62434G", - "-62435T", - "-62436A", - "-62437T", - "-62438A", - "-62439G", - "-62440A", - "-62441T", - "-62442A", - "-62443C", - "-62444C", - "-62445C", - "-62446T", - "-62447T", - "-62448C", - "-62449C", - "-62450A", - "-62451A", - "-62452A", - "-62453T", - "-62454A", - "-62455A", - "-62456T", - "-62457G", - "-62458T", - "-62459T", - "-62460C", - "-62461T", - "-62462C", - "-62463T", - "-62464T", - "-62465T", - "-62466G", - "-62467A", - "-62468T", - "-62469A", - "-62470A", - "-62471A", - "-62472A", - "-62473G", - "-62474T", - "-62475T", - "-62476C", - "-62477C", - "-62478A", - "-62479G", - "-62480A", - "-62481A", - "-62482A", - "-62483A", - "-62484T", - "-62485G", - "-62486T", - "-62487A", - "-62488G", - "-62489A", - "-62490A", - "-62491T", - "-62492T", - "-62493T", - "-62494T", - "-62495T", - "-62496T", - "-62497A", - "-62498A", - "-62499A", - "-62500A", - "-62501A", - "-62502G", - "-62503T", - "-62504T", - "-62505A", - "-62506T", - "-62507C", - "-62508T", - "-62509T", - "-62510T", - "-62511T", - "-62512G", - "-62513C", - "-62514T", - "-62515A", - "-62516T", - "-62517T", - "-62518A", - "-62519C", - "-62520T", - "-62521A", - "-62522A", - "-62523T", - "-62524A", - "-62525T", - "-62526C", - "-62527G", - "-62528T", - "-62529G", - "-62530G", - "-62531T", - "-62532T", - "-62533A", - "-62534G", - "-62535A", - "-62536C", - "-62537G", - "-62538C", - "-62539T", - "-62540T", - "-62541A", - "-62542T", - "-62543T", - "-62544A", - "-62545T", - "-62546T", - "-62547A", - "-62548A", - "-62549T", - "-62550A", - "-62551T", - "-62552G", - "-62553A", - "-62554G", - "-62555T", - "-62556G", - "-62557A", - "-62558T", - "-62559G", - "-62560A", - "-62561A", - "-62562A", - "-62563T", - "-62564C", - "-62565C", - "-62566A", - "-62567C", - "-62568A", - "-62569C", - "-62570C", - "-62571G", - "-62572C", - "-62573T", - "-62574T", - "-62575C", - "-62576T", - "-62577A", - "-62578G", - "-62579A", - "-62580T", - "-62581A", - "-62582T", - "-62583C", - "-62584G", - "-62585C", - "-62586T", - "-62587T", - "-62588T", - "-62589T", - "-62590A", - "-62591T", - "-62592T", - "-62593T", - "-62594C", - "-62595C", - "-62596A", - "-62597C", - "-62598A", - "-62599T", - "-62600T", - "-62601A", - "-62602G", - "-62603A", - "-62604T", - "-62605G", - "-62606G", - "-62607T", - "-62608A", - "-62609A", - "-62610A", - "-62611T", - "-62612C", - "-62613C", - "-62614A", - "-62615A", - "-62616T", - "-62617A", - "-62618G", - "-62619T", - "-62620G", - "-62621A", - "-62622A", - "-62623A", - "-62624C", - "-62625T", - "-62626A", - "-62627T", - "-62628C", - "-62691T", - "-62692T", - "-62693C", - "-62694G", - "-62695T", - "-62696C", - "-62697A", - "-62698A", - "-62699A", - "-62700T", - "-62701G", - "-62702A", - "-62703A", - "-62704T", - "-62705A", - "-62706A", - "-62707A", - "-62708C", - "-62709A", - "-62710A", - "-62711T", - "-62712T", - "-62713T", - "-62714C", - "-62715A", - "-62716C", - "-62717A", - "-62718A", - "-62719A", - "-62720T", - "-62721G", - "-62722G", - "-62723A", - "-62724T", - "-62725G", - "-62726T", - "-62727T", - "-62728A", - "-62729A", - "-62730T", - "-62731G", - "-62732T", - "-62733A", - "-62734T", - "-62735T", - "-62736A", - "-62737G", - "-62738T", - "-62739A", - "-62740G", - "-62741G", - "-62742A", - "-62743A", - "-62744A", - "-62745T", - "-62746T", - "-62747T", - "-62748T", - "-62749T", - "-62750T", - "-62751G", - "-62752A", - "-62753C", - "-62754G", - "-62755C", - "-62756T", - "-62757A", - "-62758G", - "-62759T", - "-62760G", - "-62761G", - "-62762A", - "-62763A", - "-62764T", - "-62765T", - "-62766G", - "-62767A", - "-62768A", - "-62769G", - "-62770A", - "-62771T", - "-62772T", - "-62773C", - "-62774T", - "-62775A", - "-62776A", - "-62777T", - "-62778G", - "-62779G", - "-62780A", - "-62781T", - "-62782G", - "-62783A", - "-62784T", - "-62785G", - "-62786T", - "-62787T", - "-62788C", - "-62789T", - "-62790A", - "-62791C", - "-62792C", - "-62793T", - "-62794A", - "-62795T", - "-62796T", - "-62797T", - "-62798C", - "-62799A", - "-62800T", - "-62801C", - "-62802C", - "-62803G", - "-62804A", - "-62805T", - "-62806A", - "-62807A", - "-62808C", - "-62809A", - "-62810T", - "-62811G", - "-62812T", - "-62813T", - "-62814A", - "-62815A", - "-62816T", - "-62817T", - "-62818T", - "-62819C", - "-62820C", - "-62821A", - "-62822A", - "-62823T", - "-62824A", - "-62825C", - "-62826C", - "-62827A", - "-62828A", - "-62829C", - "-62830G", - "-62831G", - "-62832T", - "-62833T", - "-62834T", - "-62835T", - "-62836A", - "-62837A", - "-62838T", - "-62839A", - "-62840T", - "-62841T", - "-62842T", - "-62843C", - "-62844G", - "-62845A", - "-62846T", - "-62847G", - "-62848A", - "-62849T", - "-62850A", - "-62851T", - "-62852A", - "-62853C", - "-62854G", - "-62855G", - "-62856T", - "-62857A", - "-62858G", - "-62859T", - "-62860C", - "-62863T", - "-62864C", - "-62865T", - "-62866T", - "-62867T", - "-62868C", - "-62869G", - "-62870G", - "-62871A", - "-62872C", - "-62873T", - "-62874T", - "-62875A", - "-62876T", - "-62877A", - "-62878T", - "-62879A", - "-62880G", - "-62881C", - "-62882T", - "-62883T", - "-62884A", - "-62885T", - "-62886T", - "-62887C", - "-62888C", - "-62889A", - "-62890C", - "-62891A", - "-62892A", - "-62893T", - "-62894A", - "-62895C", - "-62896G", - "-62897A", - "-62898G", - "-62899T", - "-62900C", - "-62901A", - "-62902T", - "-62903T", - "-62904A", - "-62905T", - "-62906A", - "-62907T", - "-62908A", - "-62909C", - "-62910T", - "-62911C", - "-62912C", - "-62913A", - "-62914A", - "-62915A", - "-62916A", - "-62917A", - "-62918A", - "-62919C", - "-62920A", - "-62921A", - "-62922A", - "-62923A", - "-62924T", - "-62925A", - "-62926A", - "-62927C", - "-62928T", - "-62929A", - "-62930G", - "-62931T", - "-62932A", - "-62933T", - "-62934A", - "-62935A", - "-62936A", - "-62937A", - "-62938T", - "-62939C", - "-62940T", - "-62941G", - "-62942T", - "-62943A", - "-62944T", - "-62945C", - "-62946G", - "-62947A", - "-62948A", - "-62949T", - "-62950G", - "-62951G", - "-62952G", - "-62953A", - "-62954A", - "-62955A", - "-62956A", - "-62957A", - "-62958C", - "-62959G", - "-62960A", - "-62961A", - "-62962A", - "-62963T", - "-62964T", - "-62965A", - "-62966T", - "-62967C", - "-62968G", - "-62969A", - "-62970T", - "-62971A", - "-62972T", - "-62973A", - "-62974G", - "-62975G", - "-62976T", - "-62977A", - "-62978T", - "-62979A", - "-62980G", - "-62981A", - "-62982A", - "-62983T", - "-62984C", - "-62985C", - "-62986G", - "-62987G", - "-62988A", - "-62989A", - "-62990C", - "-62991A", - "-62992T", - "-62993T", - "-62994G", - "-62995A", - "-62996A", - "-62997C", - "-62998G", - "-62999T", - "-63000A", - "-63001T", - "-63002T", - "-63003A", - "-63004A", - "-63005T", - "-63006A", - "-63007C", - "-63008T", - "-63009T", - "-63010A", - "-63011A", - "-63012T", - "-63013T", - "-63014C", - "-63015T", - "-63016T", - "-63017T", - "-63018T", - "-63019T", - "-63020C", - "-63021A", - "-63022G", - "-63023T", - "-63024G", - "-63025G", - "-63026T", - "-63027A", - "-63028A", - "-63029G", - "-63030A", - "-63031A", - "-63032C", - "-63033C", - "-63034G", - "-63035A", - "-63036T", - "-63037A", - "-63038G", - "-63039G", - "-63040T", - "-63041T", - "-63042A", - "-63043T", - "-63044T", - "-63045G", - "-63046A", - "-63047C", - "-63048A", - "-63049T", - "-63050T", - "-63051G", - "-63052T", - "-63053A", - "-63054T", - "-63055G", - "-63056G", - "-63057T", - "-63058T", - "-63059T", - "-63060T", - "-63061A", - "-63062A", - "-63063A", - "-63064T", - "-63065A", - "-63066T", - "-63067T", - "-63068C", - "-63069T", - "-63070A", - "-63071T", - "-63072A", - "-63073A", - "-63074C", - "-63075T", - "-63076T", - "-63077G", - "-63078A", - "-63079G", - "-63080A", - "-63081C", - "-63082T", - "-63083T", - "-63084G", - "-63085A", - "-63086T", - "-63087A", - "-63088G", - "-63089A", - "-63090T", - "-63091A", - "-63092T", - "-63093T", - "-63094A", - "-63095A", - "-63096T", - "-63097G", - "-63098A", - "-63099C", - "-63100G", - "-63101A", - "-63102A", - "-63103T", - "-63104T", - "-63105G", - "-63106A", - "-63107A", - "-63108A", - "-63109A", - "-63110T", - "-63111T", - "-63112A", - "-63113T", - "-63114T", - "-63115T", - "-63116T", - "-63117T", - "-63118A", - "-63119T", - "-63120C", - "-63121A", - "-63122C", - "-63123C", - "-63124A", - "-63125C", - "-63126G", - "-63127T", - "-63128G", - "-63129T", - "-63130G", - "-63131T", - "-63132T", - "-63133T", - "-63134C", - "-63135A", - "-63136G", - "-63137G", - "-63138A", - "-63139T", - "-63140C", - "-63141A", - "-63142T", - "-63143C", - "-63144G", - "-63145T", - "-63146C", - "-63147G", - "-63148A", - "-63149C", - "-63150G", - "-63151C", - "-63152C", - "-63153A", - "-63154G", - "-63155T", - "-63156T", - "-63157A", - "-63158A", - "-63159C", - "-63160C", - "-63161A", - "-63162A", - "-63163C", - "-63164C", - "-63165G", - "-63166A", - "-63167A", - "-63168T", - "-63169G", - "-63170G", - "-63171A", - "-63172G", - "-63173T", - "-63174A", - "-63175A", - "-63176A", - "-63177A", - "-63178T", - "-63179A", - "-63180A", - "-63181A", - "-63182T", - "-63183A", - "-63184T", - "-63185C", - "-63186A", - "-63187T", - "-63188T", - "-63189A", - "-63190A", - "-63191T", - "-63192A", - "-63193T", - "-63194A", - "-63195T", - "-63196G", - "-63197C", - "-63198T", - "-63199C", - "-63200T", - "-63201A", - "-63202G", - "-63203A", - "-63204T", - "-63205A", - "-63206T", - "-63207T", - "-63208A", - "-63209G", - "-63210T", - "-63211A", - "-63212T", - "-63213T", - "-63214T", - "-63215T", - "-63216T", - "-63217A", - "-63218T", - "-63219T", - "-63220A", - "-63221A", - "-63222T", - "-63223C", - "-63224C", - "-63225T", - "-63226T", - "-63227T", - "-63228G", - "-63229A", - "-63230T", - "-63231T", - "-63232A", - "-63233T", - "-63234C", - "-63235A", - "-63236T", - "-63237C", - "-63238T", - "-63239T", - "-63240C", - "-63241T", - "-63242C", - "-63243G", - "-63244T", - "-63245A", - "-63246C", - "-63247G", - "-63248C", - "-63249G", - "-63250A", - "-63251A", - "-63252T", - "-63253G", - "-63254A", - "-63255T", - "-63256T", - "-63257C", - "-63258C", - "-63259A", - "-63260T", - "-63261G", - "-63262A", - "-63263T", - "-63264C", - "-63265A", - "-63266A", - "-63267G", - "-63268A", - "-63269G", - "-63270T", - "-63271G", - "-63272A", - "-63273T", - "-63274T", - "-63275T", - "-63276G", - "-63277A", - "-63278G", - "-63279A", - "-63280A", - "-63281C", - "-63282A", - "-63283T", - "-63284C", - "-63285C", - "-63286T", - "-63287C", - "-63288C", - "-63289G", - "-63290G", - "-63291A", - "-63292G", - "-63293T", - "-63294A", - "-63295T", - "-63296T", - "-63297A", - "-63298A", - "-63299T", - "-63300G", - "-63301G", - "-63302G", - "-63303T", - "-63304T", - "-63305T", - "-63306A", - "-63307G", - "-63308T", - "-63309A", - "-63310A", - "-63311A", - "-63312C", - "-63313A", - "-63314G", - "-63315T", - "-63316C", - "-63317C", - "-63318A", - "-63319T", - "-63320C", - "-63321G", - "-63322T", - "-63323T", - "-63324G", - "-63325C", - "-63326A", - "-63327A", - "-63328T", - "-63329A", - "-63330A", - "-63331T", - "-63332A", - "-63333A", - "-63334A", - "-63335A", - "-63336G", - "-63337T", - "-63338T", - "-63339G", - "-63340T", - "-63341C", - "-63342C", - "-63343A", - "-63344A", - "-63345G", - "-63346T", - "-63347T", - "-63348A", - "-63349A", - "-63350A", - "-63351G", - "-63352G", - "-63353A", - "-63354T", - "-63355A", - "-63356T", - "-63357T", - "-63358A", - "-63359T", - "-63360G", - "-63361C", - "-63362A", - "-63363T", - "-63364T", - "-63365C", - "-63366G", - "-63367T", - "-63368T", - "-63369T", - "-63370A", - "-63371A", - "-63372A", - "-63373G", - "-63374A", - "-63375T", - "-63376A", - "-63377T", - "-63378C", - "-63379A", - "-63380C", - "-63381C", - "-63382T", - "-63383C", - "-63384A", - "-63385T", - "-63386C", - "-63387T", - "-63388A", - "-63389A", - "-63390C", - "-63391G", - "-63392G", - "-63393A", - "-63394G", - "-63395A", - "-63396C", - "-63397A", - "-63398A", - "-63399T", - "-63400T", - "-63401T", - "-63402T", - "-63403T", - "-63404T", - "-63405G", - "-63406G", - "-63407T", - "-63408A", - "-63409G", - "-63410G", - "-63411T", - "-63412T", - "-63413T", - "-63414T", - "-63415A", - "-63416G", - "-63417A", - "-63418G", - "-63419A", - "-63420C", - "-63421T", - "-63422T", - "-63423T", - "-63424G", - "-63425A", - "-63426A", - "-63427G", - "-63428C", - "-63429T", - "-63430A", - "-63431C", - "-63432T", - "-63433T", - "-63434G", - "-63435T", - "-63436T", - "-63437T", - "-63438A", - "-63439A", - "-63440C", - "-63441A", - "-63442A", - "-63443A", - "-63444G", - "-63445T", - "-63446T", - "-63447A", - "-63448T", - "-63449T", - "-63450C", - "-63451A", - "-63452T", - "-63453C", - "-63454G", - "-63455T", - "-63456C", - "-63457G", - "-63458T", - "-63459C", - "-63460T", - "-63461A", - "-63462C", - "-63463T", - "-63464A", - "-63465T", - "-63466T", - "-63467C", - "-63468T", - "-63469A", - "-63470T", - "-63471T", - "-63472T", - "-63473A", - "-63474A", - "-63475T", - "-63476T", - "-63477T", - "-63478T", - "-63479G", - "-63480T", - "-63481A", - "-63482G", - "-63483T", - "-63484T", - "-63485A", - "-63486A", - "-63487T", - "-63488T", - "-63489T", - "-63490A", - "-63491T", - "-63492C", - "C178693-", - "C178694-", - "G178696-", - "G178697-", - "C178698-", - "C178700-", - "C178702-", - "G178703-", - "C178704-" - ], - "OPG081": [ - "-1M", - "-2V", - "-3D", - "-4A", - "-5I", - "-6T", - "-7V", - "-8L", - "-9T", - "-10A", - "-11I", - "-12C", - "-13I", - "-14T", - "-15V", - "-16L", - "-17M", - "-18L", - "-19L", - "-20M", - "-21V", - "-22I", - "-23S", - "-24G", - "-25T", - "-26A", - "-27M", - "-28I", - "-29V", - "-30K", - "-31E", - "-32L", - "-33N", - "-34P", - "-35N", - "-36D", - "-37I", - "-38F", - "-39T", - "-40M", - "X41Q", - "X46N", - "-47R", - "-48T", - "-49V", - "-50T", - "-51I", - "-52F", - "-53K", - "-54Y", - "-55I", - "-56G", - "-57L", - "-58F", - "-59I", - "-60Y", - "X80*" - ], - "OPG082": [ - "-1M", - "-2N", - "-3N", - "-4F", - "-5V", - "-6K", - "-7Q", - "-8V", - "-9A", - "-10S", - "-11K", - "-12S", - "-13L", - "-14K", - "-15P", - "-16T", - "-17K", - "-18K", - "-19L", - "-20S", - "-21P", - "-22L", - "-23D", - "-24E", - "-25V", - "-26I", - "-27S", - "-28L", - "-29N", - "-30E", - "-31C", - "-32I", - "-33I", - "-34S", - "-35F", - "-36N", - "-37L", - "-38D", - "-39N", - "-40F", - "-41Y", - "-42Y", - "-43C", - "-44N", - "-45D", - "-46G", - "-47L", - "-48F", - "-49T", - "-50K", - "-51P", - "-52I", - "-53N", - "-54T", - "-55P", - "-56E", - "-57D", - "-58V", - "-59L", - "-60K", - "-61S", - "-62L", - "-63L", - "-64I", - "-65M", - "-66E", - "-67S", - "-68F", - "-69A", - "-70Y", - "-71E", - "-72K", - "-73M", - "-74I", - "-75I", - "-76K", - "-77G", - "-78L", - "-79I", - "-80K", - "-81I", - "-82L", - "-83I", - "-84S", - "-85R", - "-86A", - "-87Y", - "-88I", - "-89N", - "-90D", - "-91I", - "-92Y", - "-93F", - "-94T", - "-95P", - "-96F", - "-97G", - "-98W", - "-99L", - "-100T", - "-101G", - "-102V", - "-103D", - "-104D", - "-105D", - "-106P", - "-107E", - "-108T", - "-109H", - "-110V", - "-111V", - "-112I", - "-113K", - "-114I", - "-115I", - "-116F", - "-117N", - "-118S", - "-119S", - "-120L", - "-121I", - "-122S", - "-123I", - "-124K", - "-125S", - "-126Q", - "-127V", - "-128I", - "-129E", - "-130Y", - "-131L", - "-132K", - "-133P", - "-134Y", - "-135N", - "-136V", - "-137N", - "-138N", - "-139L", - "-140S", - "-141V", - "-142L", - "-143T", - "-144T", - "-145E", - "-146K", - "-147E", - "-148L", - "-149S", - "-150I", - "-151N", - "-152T", - "-153F", - "-154N", - "-155V", - "-156P", - "-157D", - "-158S", - "-159I", - "-160P", - "-161I", - "-162S", - "-163I", - "-164I", - "-165S", - "-166F", - "-167F", - "-168P", - "-169F", - "-170D", - "-171T", - "-172D", - "-173F", - "-174I", - "-175L", - "-176V", - "-177I", - "-178L", - "-179F", - "-180F", - "-181G", - "-182V", - "-183Y", - "-184N", - "-185D", - "-186S", - "-187Y", - "-188C", - "-189G", - "-190I", - "-191S", - "-192Y", - "-193I", - "-194S", - "-195P", - "-196K", - "-197X", - "-198X", - "-199L", - "-200P", - "-201Y", - "-202I", - "-203I", - "-204E", - "-205I", - "-206L", - "-207K", - "-208P", - "-209L", - "-210V", - "-211L", - "-212E", - "-213I", - "-214N", - "-215M", - "-216L", - "-217S", - "-218D", - "-219E", - "-220I", - "-221G", - "-222R", - "-223T", - "-224S", - "-225S", - "-226I", - "-227R", - "-228I", - "-229F", - "-230N", - "-231S", - "-232T", - "-233S", - "-234V", - "-235K", - "-236K", - "-237F", - "-238P", - "-239T", - "-240N", - "-241T", - "-242L", - "-243T", - "-244S", - "-245I", - "-246C", - "-247E", - "-248I", - "-249V", - "-250Y", - "-251S", - "-252F", - "-253D", - "-254E", - "X275K", - "-276I", - "-277V", - "-278S", - "-279L", - "-280L", - "-281D", - "-282L", - "-283P", - "-284S", - "-285N", - "-286V", - "-287E", - "-288I", - "-289K", - "-290A", - "-291I", - "-292S", - "-293R", - "-294S", - "-295G", - "-296V", - "-297D", - "-298F", - "-299I", - "-300T", - "-301H", - "-302I", - "-303N", - "-304N", - "-305K", - "-306R", - "-307L", - "-308T", - "-309T", - "-310I", - "-311L", - "-312V", - "-313I", - "-314A", - "-315K", - "-316D", - "-317N", - "-318F", - "-319L", - "-320K", - "-321N", - "-322S", - "-323T", - "-324F", - "-325S", - "-326G", - "-327T", - "-328F", - "-329I", - "-330K", - "-331E", - "-332N", - "-333I", - "-334I", - "-335W", - "-336K", - "-337G", - "-338I", - "-339Y", - "-340T", - "-341Y", - "-342R", - "-343I", - "-344I", - "-345K", - "-346S", - "-347S", - "-348F", - "-349P", - "-350V", - "-351P", - "-352T", - "-353I", - "-354K", - "-355S", - "-356V", - "-357T", - "-358N", - "-359K", - "X366H", - "-367C", - "-368F", - "-369V", - "-370N", - "-371S", - "-372Q", - "-373Y", - "-374T", - "-375T", - "-376R", - "-377T", - "-378L", - "-379S", - "-380H", - "-381I", - "-382L", - "-383X" - ], - "OPG083": [ - "-409D", - "-410K", - "-411L", - "-412T", - "-413T", - "-414K", - "-415L", - "-416N", - "-417R", - "-418I", - "-419V", - "-420D", - "-421D", - "-422D", - "-423E", - "-424*" - ] - }, - "labels": { - "aa": "OPG081: -1M, -2V, -3D, -4A, -5I, -6T, -7V, -8L, -9T, -10A, -11I, -12C, -13I, -14T, -15V, -16L, -17M, -18L, -19L, -20M, -21V, -22I, -23S, -24G, -25T, -26A, -27M, -28I, -29V, -30K, -31E, -32L, -33N, -34P, -35N, -36D, -37I, -38F, -39T, -40M, X41Q, X46N, -47R, -48T, -49V, -50T, -51I, -52F, -53K, -54Y, -55I, -56G, -57L, -58F, -59I, -60Y, X80*; OPG082: -1M, -2N, -3N, -4F, -5V, -6K, -7Q, -8V, -9A, -10S, -11K, -12S, -13L, -14K, -15P, -16T, -17K, -18K, -19L, -20S, -21P, -22L, -23D, -24E, -25V, -26I, -27S, -28L, -29N, -30E, -31C, -32I, -33I, -34S, -35F, -36N, -37L, -38D, -39N, -40F, -41Y, -42Y, -43C, -44N, -45D, -46G, -47L, -48F, -49T, -50K, -51P, -52I, -53N, -54T, -55P, -56E, -57D, -58V, -59L, -60K, -61S, -62L, -63L, -64I, -65M, -66E, -67S, -68F, -69A, -70Y, -71E, -72K, -73M, -74I, -75I, -76K, -77G, -78L, -79I, -80K, -81I, -82L, -83I, -84S, -85R, -86A, -87Y, -88I, -89N, -90D, -91I, -92Y, -93F, -94T, -95P, -96F, -97G, -98W, -99L, -100T, -101G, -102V, -103D, -104D, -105D, -106P, -107E, -108T, -109H, -110V, -111V, -112I, -113K, -114I, -115I, -116F, -117N, -118S, -119S, -120L, -121I, -122S, -123I, -124K, -125S, -126Q, -127V, -128I, -129E, -130Y, -131L, -132K, -133P, -134Y, -135N, -136V, -137N, -138N, -139L, -140S, -141V, -142L, -143T, -144T, -145E, -146K, -147E, -148L, -149S, -150I, -151N, -152T, -153F, -154N, -155V, -156P, -157D, -158S, -159I, -160P, -161I, -162S, -163I, -164I, -165S, -166F, -167F, -168P, -169F, -170D, -171T, -172D, -173F, -174I, -175L, -176V, -177I, -178L, -179F, -180F, -181G, -182V, -183Y, -184N, -185D, -186S, -187Y, -188C, -189G, -190I, -191S, -192Y, -193I, -194S, -195P, -196K, -197X, -198X, -199L, -200P, -201Y, -202I, -203I, -204E, -205I, -206L, -207K, -208P, -209L, -210V, -211L, -212E, -213I, -214N, -215M, -216L, -217S, -218D, -219E, -220I, -221G, -222R, -223T, -224S, -225S, -226I, -227R, -228I, -229F, -230N, -231S, -232T, -233S, -234V, -235K, -236K, -237F, -238P, -239T, -240N, -241T, -242L, -243T, -244S, -245I, -246C, -247E, -248I, -249V, -250Y, -251S, -252F, -253D, -254E, X275K, -276I, -277V, -278S, -279L, -280L, -281D, -282L, -283P, -284S, -285N, -286V, -287E, -288I, -289K, -290A, -291I, -292S, -293R, -294S, -295G, -296V, -297D, -298F, -299I, -300T, -301H, -302I, -303N, -304N, -305K, -306R, -307L, -308T, -309T, -310I, -311L, -312V, -313I, -314A, -315K, -316D, -317N, -318F, -319L, -320K, -321N, -322S, -323T, -324F, -325S, -326G, -327T, -328F, -329I, -330K, -331E, -332N, -333I, -334I, -335W, -336K, -337G, -338I, -339Y, -340T, -341Y, -342R, -343I, -344I, -345K, -346S, -347S, -348F, -349P, -350V, -351P, -352T, -353I, -354K, -355S, -356V, -357T, -358N, -359K, X366H, -367C, -368F, -369V, -370N, -371S, -372Q, -373Y, -374T, -375T, -376R, -377T, -378L, -379S, -380H, -381I, -382L, -383X; OPG083: -409D, -410K, -411L, -412T, -413T, -414K, -415L, -416N, -417R, -418I, -419V, -420D, -421D, -422D, -423E, -424*" - } - } - }, - { - "name": "28022023_anal", - "node_attrs": { - "div": 562, - "author": { - "author": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K.", - "value": "Mertes,H., Rezende,A.M., Naesens,R., de Block,T., Michiels,J., Coppens,J., Van Dijck,C., Bomans,P., Arien,K., Bottieau,E., Van Esbroeck,M., Liesenborghs,L., Vercauteren,K." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "date": { - "value": "2023-02-28" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "28022023_anal" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ672579" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A2611-", - "C2612-", - "A2613-", - "C2614-", - "G2615-", - "A2616-", - "T2617-", - "A2618-", - "G2619-", - "A2620-", - "A2622-", - "A2623-", - "C2624-", - "A2625-", - "T2626-", - "A2627-", - "G2628-", - "A2629-", - "T2630-", - "T2631-", - "A2632-", - "C2633-", - "G2634-", - "G2635-", - "C2636-", - "T2637-", - "T2638-", - "C2639-", - "T2640-", - "G2641-", - "T2642-", - "A2643-", - "T2644-", - "T2645-", - "C2646-", - "G2647-", - "T2648-", - "T2649-", - "G2650-", - "T2651-", - "C2652-", - "T2653-", - "T2654-", - "T2655-", - "A2656-", - "C2657-", - "A2658-", - "C2659-", - "T2660-", - "T2661-", - "T39397C", - "A47693-", - "C47694-", - "T47695-", - "C47696-", - "T47778-", - "T47779-", - "C47780-", - "C47781-", - "A47782-", - "A47783-", - "A47784-", - "T47785-", - "A47786-", - "A47787-", - "T47788-", - "C47789-", - "A47790-", - "G47791-", - "A47792-", - "A47793-", - "A47794-", - "A47795-", - "C47796-", - "T47797-", - "T47798-", - "A47799-", - "T47800-", - "A47801-", - "A47802-", - "A47803-", - "C47804-", - "T47805-", - "A47806-", - "T47807-", - "T47808-", - "C47809-", - "T47810-", - "C47811-", - "G47812-", - "G47813-", - "A47814-", - "C47815-", - "A47816-", - "T47817-", - "T47818-", - "T47819-", - "C47820-", - "A47821-", - "G47822-", - "T47823-", - "C47824-", - "A47825-", - "T47826-", - "T47827-", - "G47828-", - "G47829-", - "C47830-", - "A47831-", - "A47832-", - "A47833-", - "G47834-", - "C47835-", - "A47836-", - "T47837-", - "C47838-", - "A47839-", - "C47840-", - "A47841-", - "G47842-", - "A47843-", - "A47844-", - "T47845-", - "C47846-", - "C47847-", - "G47848-", - "A47849-", - "G47850-", - "T47851-", - "A47852-", - "A47853-", - "G47854-", - "A47855-", - "T47856-", - "G47857-", - "A47858-", - "T47859-", - "A47860-", - "T47861-", - "A47862-", - "T47863-", - "G47864-", - "C47865-", - "T47866-", - "C47867-", - "G47868-", - "C47869-", - "T47870-", - "G47871-", - "C47872-", - "T47873-", - "T47874-", - "T47875-", - "A47876-", - "C47877-", - "A47878-", - "T47879-", - "G47880-", - "T47881-", - "T47882-", - "T47883-", - "C47884-", - "C47885-", - "C47886-", - "A47887-", - "A47888-", - "T47889-", - "T47890-", - "T47891-", - "G47892-", - "T47893-", - "T47894-", - "T47895-", - "G47896-", - "G47897-", - "A47898-", - "G47899-", - "A47900-", - "T47901-", - "G47902-", - "A47903-", - "C47904-", - "C47905-", - "A47906-", - "T47907-", - "A47908-", - "G47909-", - "A47910-", - "T47911-", - "T47912-", - "C47913-", - "A47914-", - "T47915-", - "T47916-", - "T47917-", - "G47918-", - "T47919-", - "T47920-", - "A47921-", - "T47922-", - "A47923-", - "G47924-", - "A47925-", - "A47926-", - "T47927-", - "G47928-", - "C47929-", - "A47930-", - "T47931-", - "C47932-", - "C47933-", - "A47934-", - "A47935-", - "C47936-", - "A47937-", - "T47938-", - "T47939-", - "G47940-", - "T47941-", - "T47942-", - "C47943-", - "A47944-", - "T47945-", - "G47946-", - "A47947-", - "T47948-", - "A47949-", - "T47950-", - "A47951-", - "G47952-", - "T47953-", - "T47954-", - "G47955-", - "A47956-", - "A47957-", - "T47958-", - "C47959-", - "A47960-", - "T47961-", - "G47962-", - "A48012-", - "A48013-", - "T48014-", - "A48015-", - "A48016-", - "A48017-", - "T48018-", - "G61785-", - "G61786-", - "C61787-", - "T61788-", - "A61789-", - "A61815-", - "G61816-", - "T61817-", - "A61818-", - "C61819-", - "A61820-", - "A61821-", - "G61822-", - "T61823-", - "G61824-", - "G61825-", - "C61826-", - "T61827-", - "G61828-", - "C61829-", - "T61830-", - "A61831-", - "T61832-", - "T61833-", - "T61834-", - "C61835-", - "G61836-", - "G61837-", - "C61838-", - "T61839-", - "G61840-", - "C61841-", - "C61842-", - "A61843-", - "G61844-", - "A61845-", - "G61846-", - "T61847-", - "G61848-", - "T61849-", - "C61850-", - "C61851-", - "A61852-", - "A61853-", - "T61854-", - "T61855-", - "C61856-", - "T61857-", - "A61858-", - "C61859-", - "C61860-", - "G61861-", - "T61862-", - "T61863-", - "G61864-", - "T61865-", - "T61866-", - "A61867-", - "C61868-", - "T61869-", - "C61870-", - "C61871-", - "A61872-", - "T61873-", - "T61874-", - "A61875-", - "T61876-", - "A61877-", - "T61878-", - "A61879-", - "T61880-", - "T61881-", - "C61882-", - "C61883-", - "T61884-", - "T61885-", - "G61886-", - "A61887-", - "A61888-", - "T61889-", - "A61890-", - "A61891-", - "C61892-", - "C61893-", - "T61894-", - "T61895-", - "C61896-", - "A61897-", - "T61898-", - "A61899-", - "G61900-", - "C61901-", - "T61902-", - "A61903-", - "T61904-", - "T61905-", - "T61906-", - "T61907-", - "A61908-", - "A61909-", - "T61910-", - "A61911-", - "G61912-", - "G61913-", - "A61914-", - "T61915-", - "C61916-", - "T61917-", - "A61918-", - "T61919-", - "A61920-", - "T61921-", - "G61922-", - "A61923-", - "T61924-", - "C61925-", - "A61926-", - "G61927-", - "T61928-", - "G61929-", - "T61930-", - "T61931-", - "T61932-", - "A61933-", - "A61934-", - "G61935-", - "C61936-", - "C61937-", - "A61938-", - "T61939-", - "A61940-", - "G61941-", - "C61942-", - "A61943-", - "C61944-", - "A61945-", - "A61946-", - "T61947-", - "T61948-", - "T61949-", - "T61950-", - "C61951-", - "T61952-", - "A61953-", - "A61954-", - "T61955-", - "A61956-", - "C61957-", - "G61958-", - "A61959-", - "G61960-", - "A61961-", - "C61962-", - "G61963-", - "T61964-", - "G61965-", - "A61966-", - "T61967-", - "T61968-", - "T61969-", - "T61970-", - "A61971-", - "T61972-", - "C61973-", - "A61974-", - "A61975-", - "A61976-", - "C61977-", - "A61978-", - "T61979-", - "G61980-", - "A61981-", - "C61982-", - "A61983-", - "T61984-", - "T61985-", - "T61986-", - "T61987-", - "C61988-", - "C61989-", - "T61990-", - "T61991-", - "G61992-", - "T61993-", - "A61994-", - "T61995-", - "C61996-", - "C61997-", - "A61998-", - "T61999-", - "T62000-", - "T62001-", - "C62002-", - "G62003-", - "T62004-", - "T62005-", - "T62006-", - "A62007-", - "A62008-", - "T62009-", - "G62010-", - "A62011-", - "C62012-", - "A62013-", - "A62014-", - "A62015-", - "C62016-", - "A62017-", - "T62018-", - "T62019-", - "T62020-", - "T62021-", - "T62022-", - "G62023-", - "T62024-", - "T62025-", - "G62026-", - "G62027-", - "T62028-", - "G62029-", - "T62030-", - "A62031-", - "A62032-", - "T62033-", - "A62034-", - "A62035-", - "T62043-", - "A62044-", - "T62045-", - "T62046-", - "T62047-", - "A62048-", - "A62049-", - "T62050-", - "T62051-", - "T62052-", - "T62053-", - "T62054-", - "C62055-", - "A62056-", - "T62057-", - "T62058-", - "A62059-", - "A62060-", - "T62061-", - "A62062-", - "G62063-", - "G62064-", - "G62065-", - "A62066-", - "T62067-", - "T62068-", - "T62069-", - "G62070-", - "A62071-", - "C62072-", - "G62073-", - "T62074-", - "A62075-", - "T62076-", - "G62077-", - "T62078-", - "A62079-", - "G62080-", - "C62081-", - "G62082-", - "T62083-", - "A62084-", - "C62085-", - "A62086-", - "A62087-", - "A62088-", - "A62089-", - "T62090-", - "T62091-", - "A62092-", - "T62093-", - "C62094-", - "G62095-", - "T62096-", - "T62097-", - "C62098-", - "C62099-", - "T62100-", - "G62101-", - "G62102-", - "T62103-", - "A62104-", - "T62105-", - "T62149-", - "T62150-", - "A62151-", - "A62152-", - "A62153-", - "C62154-", - "T62155-", - "T62156-", - "T62157-", - "A62158-", - "A62159-", - "T62160-", - "G62161-", - "A62162-", - "T62163-", - "T62629-", - "T62630-", - "T62631-", - "T62632-", - "T62633-", - "A62634-", - "G62635-", - "G62636-", - "A62637-", - "A62638-", - "T62639-", - "G62640-", - "T62641-", - "A62642-", - "T62643-", - "G62644-", - "G62645-", - "A62646-", - "C62647-", - "T62648-", - "C62649-", - "G62650-", - "C62651-", - "G62652-", - "T62653-", - "T62654-", - "T62655-", - "A62656-", - "G62657-", - "A62658-", - "G62659-", - "G62660-", - "A62661-", - "G62662-", - "T62663-", - "G62664-", - "A62665-", - "A62666-", - "C62667-", - "G62668-", - "T62669-", - "C62670-", - "T62671-", - "T62672-", - "C62673-", - "G62674-", - "G62675-", - "A62676-", - "G62677-", - "T62678-", - "A62679-", - "G62680-", - "T62681-", - "A62682-", - "A62683-", - "A62684-", - "G62685-", - "G62686-", - "A62687-", - "T62688-", - "G62689-", - "A62690-", - "A63493-", - "C63494-", - "A63495-", - "T63496-", - "A63497-", - "T63498-", - "C63499-", - "A63500-", - "C63501-", - "A63502-", - "T63503-", - "T63504-", - "A63505-", - "C70785-", - "G70786-", - "T70787-", - "A70788-", - "T70789-", - "A70790-", - "T70827-", - "C70828-", - "A70869-", - "T70870-", - "T70871-", - "T70872-", - "A70873-", - "G70874-", - "A70875-", - "G70876-", - "A70877-", - "G70878-", - "C70879-", - "G70880-", - "T70881-", - "G70882-", - "C70883-", - "C70884-", - "G70907-", - "C70908-", - "A70909-", - "T70910-", - "T70911-", - "A70912-", - "G70913-", - "A70914-", - "A70915-", - "C70916-", - "C70917-", - "A70918-", - "C70919-", - "G70920-", - "T70921-", - "C70938-", - "A70939-", - "G70940-", - "A70962-", - "T70969-", - "T70970-", - "T70971-", - "C70972-", - "G70973-", - "A70974-", - "A70975-", - "A70976-", - "A70977-", - "T70978-", - "A70979-", - "C70980-", - "T70981-", - "A70982-", - "A70983-", - "A70984-", - "T70985-", - "C70986-", - "T71023-", - "G71024-", - "G71025-", - "A71026-", - "T71027-", - "A71028-", - "T71029-", - "T71030-", - "C71031-", - "T71032-", - "A71033-", - "A71034-", - "C71035-", - "G71036-", - "A71037-", - "A71038-", - "A71039-", - "A71040-", - "C71041-", - "T71042-", - "G71043-", - "T71044-", - "A71045-", - "A71046-", - "C71047-", - "A71048-", - "C71049-", - "C71050-", - "A71051-", - "T71052-", - "A71053-", - "G71054-", - "T71055-", - "G71056-", - "T71057-", - "T71058-", - "C71059-", - "G71060-", - "G71061-", - "C71062-", - "A71063-", - "T71064-", - "C71065-", - "T71066-", - "A71067-", - "T71068-", - "A71069-", - "A71070-", - "G71071-", - "G71072-", - "A71073-", - "T71074-", - "A71075-", - "A71076-", - "T71077-", - "T71078-", - "T71079-", - "A71080-", - "C71081-", - "T71082-", - "A71083-", - "C71084-", - "T71085-", - "G71086-", - "A71087-", - "G71088-", - "T71089-", - "A71090-", - "T71091-", - "A71092-", - "C71113-", - "G71114-", - "A71115-", - "T71116-", - "A71117-", - "G71118-", - "T71119-", - "C71120-", - "T71121-", - "G71122-", - "T71123-", - "T71124-", - "A71125-", - "A71126-", - "T71127-", - "A71128-", - "A71129-", - "C71130-", - "C71131-", - "A71132-", - "A71133-", - "T71134-", - "T71172-", - "T71173-", - "A71174-", - "A71175-", - "A71176-", - "A71177-", - "A71178-", - "A71179-", - "T71180-", - "G71181-", - "G71182-", - "T71183-", - "G71184-", - "T71185-", - "T71186-", - "C71187-", - "C71188-", - "A71189-", - "G71190-", - "C71191-", - "T71192-", - "C71193-", - "G71194-", - "T71195-", - "G71196-", - "T71197-", - "G71198-", - "T71199-", - "T71200-", - "C71201-", - "T71202-", - "A71203-", - "C71204-", - "A71205-", - "T71206-", - "G71207-", - "C71208-", - "G71209-", - "G71210-", - "C71211-", - "A71212-", - "A71213-", - "A71214-", - "G71215-", - "A71216-", - "T71217-", - "A71218-", - "T71219-", - "T71220-", - "T71221-", - "C71222-", - "T71223-", - "C71224-", - "A71225-", - "C71226-", - "G71227-", - "A71228-", - "A71229-", - "C71230-", - "G71231-", - "A71232-", - "T71233-", - "A71234-", - "T71235-", - "A71236-", - "A71237-", - "A71238-", - "T71239-", - "T71240-", - "G71241-", - "A71242-", - "T71243-", - "T71244-", - "A71245-", - "T71246-", - "A71247-", - "C71248-", - "G71249-", - "A71250-", - "A71251-", - "A71252-", - "A71253-", - "A71254-", - "A71255-", - "A71256-", - "T71257-", - "C71258-", - "A71259-", - "T71260-", - "T71261-", - "A71262-", - "A71263-", - "A71264-", - "G71265-", - "G71266-", - "A71267-", - "T71268-", - "G71269-", - "T71270-", - "A71271-", - "C71272-", - "T71273-", - "A71274-", - "G71275-", - "T71276-", - "C71277-", - "A71278-", - "G71279-", - "T71280-", - "G71281-", - "T71282-", - "A71283-", - "A71284-", - "A71285-", - "G71286-", - "A71287-", - "A71288-", - "C71289-", - "G71290-", - "A71291-", - "A71292-", - "T71293-", - "G71294-", - "T71295-", - "T71296-", - "G71297-", - "T71298-", - "A71299-", - "G71300-", - "G71301-", - "T71302-", - "T71303-", - "A71304-", - "A71305-", - "A71306-", - "A71307-", - "T71308-", - "T71309-", - "A71310-", - "T71311-", - "C71312-", - "T71313-", - "A71314-", - "C71315-", - "A71316-", - "C71317-", - "A71318-", - "A71319-", - "A71320-", - "T71321-", - "A71322-", - "G71323-", - "A71324-", - "A71325-", - "C71326-", - "C71327-", - "T71328-", - "C71329-", - "A71330-", - "A71331-", - "C71332-", - "G71333-", - "T71334-", - "A71335-", - "A71336-", - "C71337-", - "T71338-", - "T71339-", - "A71340-", - "A71341-", - "C71342-", - "A71343-", - "G71344-", - "T71345-", - "G71346-", - "C71347-", - "A71348-", - "A71349-", - "C71350-", - "C71351-", - "T71352-", - "C71353-", - "T71354-", - "A71355-", - "T71356-", - "T71357-", - "G71358-", - "G71359-", - "A71360-", - "T71361-", - "A71362-", - "T71363-", - "A71364-", - "A71365-", - "A71366-", - "C71367-", - "T71368-", - "A71369-", - "A71370-", - "T71371-", - "G71372-", - "G71373-", - "A71374-", - "T71375-", - "C71376-", - "C71377-", - "G71378-", - "G71379-", - "T71380-", - "T71381-", - "A71382-", - "A71383-", - "T71384-", - "T71385-", - "T71386-", - "T71387-", - "A71388-", - "T71389-", - "C71390-", - "A71391-", - "A71392-", - "G71393-", - "A71394-", - "C71395-", - "A71396-", - "T71397-", - "A71398-", - "T71399-", - "G71400-", - "C71401-", - "G71402-", - "C71403-", - "C71404-", - "T71405-", - "A71406-", - "G71407-", - "A71408-", - "G71409-", - "G71410-", - "T71411-", - "T71412-", - "C71413-", - "T71414-", - "A71415-", - "T71416-", - "T71417-", - "A71418-", - "T71419-", - "T71420-", - "T71421-", - "T71422-", - "T71423-", - "A71424-", - "T71425-", - "T71426-", - "T71500-", - "A71501-", - "T71502-", - "T71503-", - "A71504-", - "T71505-", - "C71506-", - "G71507-", - "G71508-", - "A71509-", - "A71510-", - "C71511-", - "A71512-", - "C71513-", - "T71514-", - "T71515-", - "G71516-", - "G71517-", - "T71518-", - "A71519-", - "G71520-", - "T71521-", - "T71522-", - "G71523-", - "A71524-", - "A71525-", - "T71526-", - "C71527-", - "T71528-", - "A71529-", - "C71530-", - "C71531-", - "T71532-", - "A71533-", - "T71534-", - "A71535-", - "G71536-", - "A71537-", - "A71538-", - "A71539-", - "A71540-", - "G71541-", - "G71542-", - "A71543-", - "G71544-", - "T71545-", - "T71546-", - "A71547-", - "G71548-", - "A71549-", - "A71550-", - "T71551-", - "A71552-", - "G71553-", - "T71554-", - "C71555-", - "C71556-", - "C71557-", - "A71558-", - "T71559-", - "T71560-", - "G71561-", - "G71562-", - "A71563-", - "T71564-", - "A71565-", - "G71566-", - "A71567-", - "T71568-", - "T71569-", - "T71570-", - "T71571-", - "T71572-", - "T71573-", - "G71574-", - "A71575-", - "A71576-", - "G71577-", - "G71578-", - "A71579-", - "T71580-", - "A71581-", - "T71582-", - "C71583-", - "T71584-", - "T71585-", - "A71586-", - "G71587-", - "T71588-", - "G71589-", - "C71590-", - "A71591-", - "A71592-", - "A71593-", - "A71594-", - "G71595-", - "T71596-", - "A71597-", - "T71598-", - "A71599-", - "C71600-", - "A71601-", - "T71602-", - "G71603-", - "T71604-", - "T71605-", - "A71606-", - "G71607-", - "A71608-", - "G71609-", - "A71610-", - "A71611-", - "T71612-", - "A71613-", - "T71614-", - "T71615-", - "C71616-", - "A71617-", - "A71618-", - "G71619-", - "T71620-", - "T71621-", - "A71622-", - "T71623-", - "G71624-", - "A71625-", - "A71626-", - "A71627-", - "A71628-", - "T71629-", - "A71630-", - "G71631-", - "C71632-", - "A71633-", - "G71634-", - "C71635-", - "T71674-", - "T71675-", - "G71676-", - "G71677-", - "A71701-", - "A71702-", - "T71703-", - "T71704-", - "G71705-", - "G71706-", - "T71707-", - "A71708-", - "G71709-", - "C71710-", - "T71711-", - "G71712-", - "A71713-", - "A71714-", - "T71715-", - "G71716-", - "T71717-", - "T71718-", - "A71719-", - "T71720-", - "A71721-", - "A71722-", - "A71723-", - "A71724-", - "A71725-", - "T71726-", - "G71727-", - "C71728-", - "C71729-", - "G71730-", - "G71731-", - "T71732-", - "A71733-", - "T71734-", - "T71735-", - "G71736-", - "A71737-", - "T71738-", - "A71739-", - "C71740-", - "A71741-", - "T71742-", - "C71743-", - "G71744-", - "T71745-", - "C71746-", - "T71747-", - "A71748-", - "A71749-", - "A71750-", - "C71751-", - "G71752-", - "A71753-", - "A71754-", - "T71755-", - "A71756-", - "T71757-", - "T71758-", - "A71759-", - "G71760-", - "G71761-", - "T71762-", - "A71763-", - "A71764-", - "A71765-", - "G71766-", - "A71767-", - "T71768-", - "A71769-", - "T71770-", - "T71771-", - "T71772-", - "T71773-", - "T71774-", - "C71775-", - "T71776-", - "G71777-", - "A71778-", - "G71779-", - "C71780-", - "C71781-", - "A71782-", - "A71783-", - "A71784-", - "A71785-", - "C71786-", - "T71787-", - "T71788-", - "T71789-", - "A71790-", - "C71791-", - "A71792-", - "G71793-", - "A71794-", - "T71795-", - "G71796-", - "A71797-", - "T71798-", - "A71799-", - "A71800-", - "T71801-", - "A71802-", - "G71803-", - "A71804-", - "T71805-", - "C71855-", - "T71908-", - "T71909-", - "C71910-", - "T71911-", - "T71912-", - "T71913-", - "T71914-", - "T71915-", - "C71916-", - "T71917-", - "T71918-", - "A71919-", - "A71920-", - "C71921-", - "G71922-", - "T71923-", - "T71924-", - "G71925-", - "T71926-", - "T71927-", - "T71928-", - "G71929-", - "C71930-", - "C71931-", - "A71932-", - "T71933-", - "C71934-", - "A71935-", - "C71936-", - "T71937-", - "C71938-", - "T71939-", - "C71940-", - "A71941-", - "T71942-", - "A71943-", - "A71944-", - "T71945-", - "G71946-", - "T71947-", - "A71948-", - "A71949-", - "A71950-", - "G71951-", - "A71952-", - "T71953-", - "A71954-", - "T71955-", - "T71956-", - "C71957-", - "T71958-", - "A71959-", - "A71960-", - "A71961-", - "A71962-", - "T71963-", - "G71964-", - "G71965-", - "T71966-", - "A71967-", - "A71968-", - "A71969-", - "C71970-", - "T71971-", - "T71972-", - "T71973-", - "T71974-", - "G71975-", - "C71976-", - "A71977-", - "T71978-", - "A71979-", - "T71980-", - "C71981-", - "G71982-", - "G71983-", - "A71984-", - "T71985-", - "G71986-", - "C71987-", - "A71988-", - "G71989-", - "A71990-", - "A71991-", - "A71992-", - "T71993-", - "T71994-", - "G71995-", - "G71996-", - "T71997-", - "A71998-", - "T71999-", - "A72000-", - "A72001-", - "A72002-", - "T72003-", - "G72004-", - "T72005-", - "T72006-", - "G72007-", - "T72008-", - "A72009-", - "A72010-", - "T72011-", - "T72012-", - "G72013-", - "T72014-", - "A72015-", - "T72016-", - "T72017-", - "A72018-", - "T72019-", - "T72020-", - "T72021-", - "C72022-", - "C72023-", - "C72024-", - "G72025-", - "T72026-", - "C72027-", - "A72028-", - "A72029-", - "T72030-", - "G72031-", - "G72032-", - "A72033-", - "C72034-", - "T72035-", - "A72036-", - "G72037-", - "T72038-", - "C72039-", - "A72040-", - "C72041-", - "A72042-", - "G72043-", - "C72044-", - "T72045-", - "C72046-", - "C72047-", - "A72048-", - "T72049-", - "C72050-", - "A72051-", - "G72052-", - "T72053-", - "T72054-", - "T72055-", - "T72056-", - "A72057-", - "T72058-", - "A72059-", - "T72060-", - "C72061-", - "C72062-", - "T72063-", - "T72064-", - "T72065-", - "A72066-", - "G72067-", - "A72068-", - "G72069-", - "T72070-", - "A72071-", - "T72072-", - "T72073-", - "T72074-", - "C72075-", - "T72076-", - "C72077-", - "A72078-", - "C72079-", - "T72080-", - "C72081-", - "G72082-", - "T72083-", - "G72084-", - "T72085-", - "C72086-", - "T72087-", - "A72088-", - "G72089-", - "C72090-", - "A72091-", - "T72092-", - "T72093-", - "C72094-", - "T72095-", - "A72096-", - "G72097-", - "A72098-", - "G72099-", - "C72100-", - "A72101-", - "T72102-", - "T72103-", - "C72104-", - "C72105-", - "A72106-", - "T72107-", - "G72108-", - "A72109-", - "T72110-", - "C72111-", - "T72112-", - "G72113-", - "T72114-", - "T72115-", - "T72116-", - "A72117-", - "T72118-", - "C72119-", - "G72120-", - "T72121-", - "T72122-", - "G72123-", - "A72124-", - "T72125-", - "A72126-", - "T72127-", - "T72128-", - "G72129-", - "G72130-", - "C72131-", - "C72132-", - "G72133-", - "G72134-", - "A72135-", - "A72136-", - "A72137-", - "G72138-", - "A72139-", - "T72140-", - "A72141-", - "G72142-", - "A72143-", - "T72144-", - "T72145-", - "T72146-", - "T72147-", - "T72148-", - "T72149-", - "A72150-", - "T72151-", - "T72152-", - "T72153-", - "T72154-", - "T72155-", - "T72156-", - "A72157-", - "T72158-", - "T72159-", - "A72160-", - "T72161-", - "A72162-", - "T72163-", - "T72164-", - "A72165-", - "C72166-", - "T72167-", - "A72168-", - "T72169-", - "T72170-", - "G72171-", - "G72172-", - "C72173-", - "A72174-", - "A72175-", - "T72176-", - "T72177-", - "G72178-", - "T72179-", - "A72180-", - "G72181-", - "A72182-", - "T72183-", - "A72184-", - "T72185-", - "A72186-", - "A72187-", - "C72188-", - "T72189-", - "T72190-", - "C72191-", - "T72192-", - "G72193-", - "G72194-", - "T72195-", - "A72196-", - "A72197-", - "A72198-", - "T72199-", - "A72200-", - "T72201-", - "T72202-", - "T72203-", - "T72204-", - "T72205-", - "C72206-", - "T72207-", - "A72208-", - "C72209-", - "C72210-", - "T72211-", - "T72212-", - "T72213-", - "T72214-", - "C72215-", - "A72216-", - "A72217-", - "T72218-", - "C72219-", - "T72220-", - "C72221-", - "T72222-", - "T72223-", - "C72224-", - "T72225-", - "A72226-", - "T72227-", - "T72228-", - "T72229-", - "T72230-", - "C72231-", - "A72232-", - "A72233-", - "G72234-", - "C72235-", - "C72236-", - "G72237-", - "G72238-", - "C72239-", - "T72240-", - "A72241-", - "T72242-", - "A72243-", - "T72244-", - "A72245-", - "T72246-", - "T72247-", - "C72248-", - "T72249-", - "G72250-", - "C72251-", - "T72252-", - "A72253-", - "T72254-", - "A72255-", - "T72256-", - "T72257-", - "G72258-", - "T72259-", - "T72260-", - "A72261-", - "C72262-", - "T72263-", - "A72264-", - "G72265-", - "T72266-", - "A72267-", - "T72268-", - "C72269-", - "A72270-", - "A72271-", - "T72272-", - "A72273-", - "C72274-", - "C72275-", - "T72276-", - "T72277-", - "T72278-", - "T72279-", - "C72280-", - "T72281-", - "G72282-", - "G72283-", - "C72284-", - "T72285-", - "A72286-", - "A72287-", - "G72288-", - "A72289-", - "A72290-", - "G72291-", - "T72292-", - "C72293-", - "A72294-", - "T72295-", - "A72296-", - "T72297-", - "G72298-", - "T72299-", - "G72300-", - "G72301-", - "T72302-", - "A72303-", - "T72304-", - "T72305-", - "C72306-", - "A72307-", - "C72308-", - "T72309-", - "A72310-", - "T72311-", - "A72312-", - "T72313-", - "C72314-", - "A72315-", - "G72316-", - "T72317-", - "T72318-", - "T72319-", - "T72320-", - "A72321-", - "A72322-", - "C72323-", - "T72324-", - "G72325-", - "G72326-", - "T72327-", - "A72328-", - "G72329-", - "T72330-", - "T72331-", - "C72332-", - "C72333-", - "A72334-", - "T72335-", - "T72336-", - "A72337-", - "G72338-", - "C72339-", - "C72340-", - "T72341-", - "T72342-", - "T72343-", - "C72344-", - "C72345-", - "A72346-", - "C72347-", - "T72348-", - "T72349-", - "C72350-", - "T72351-", - "G72352-", - "C72353-", - "A72354-", - "G72355-", - "A72356-", - "A72357-", - "T72358-", - "A72359-", - "A72360-", - "T72361-", - "T72362-", - "A72363-", - "G72364-", - "A72365-", - "A72366-", - "A72367-", - "T72368-", - "T72369-", - "G72370-", - "G72371-", - "T72372-", - "T72373-", - "C72374-", - "T72375-", - "T72376-", - "T72377-", - "A72378-", - "C72379-", - "C72380-", - "A72381-", - "G72382-", - "A72383-", - "A72384-", - "A72385-", - "A72386-", - "T72387-", - "C72388-", - "C72389-", - "A72390-", - "G72391-", - "C72392-", - "A89100-", - "A89101-", - "A89102-", - "C89145-", - "T89146-", - "T89147-", - "G89148-", - "T89166-", - "A89219-", - "A89220-", - "A89221-", - "T89222-", - "A89223-", - "G89224-", - "C89225-", - "A89373-", - "C89374-", - "T89375-", - "T89376-", - "A89377-", - "T89378-", - "A89379-", - "T89380-", - "T89381-", - "C89382-", - "G89383-", - "T89384-", - "G89385-", - "T89386-", - "C89387-", - "T89388-", - "A89389-", - "G89390-", - "T89391-", - "A89392-", - "G89393-", - "A89394-", - "T89700-", - "-178687A", - "-178688T", - "-178689A", - "-178690A", - "-178691A", - "-178692T", - "-178695A", - "-178699T", - "-178701T", - "A194550-", - "G194551-", - "T194552-", - "G194553-", - "T194554-", - "A194555-", - "A194556-", - "A194557-", - "G194558-", - "A194559-", - "C194560-", - "A194561-", - "A194562-", - "C194563-", - "G194564-", - "A194565-", - "A194566-", - "T194567-", - "A194568-", - "C194569-", - "A194570-", - "G194571-", - "A194572-", - "A194573-", - "G194574-", - "C194575-", - "C194576-", - "G194577-", - "T194578-", - "A194579-", - "A194580-", - "T194581-", - "C194582-", - "T194583-", - "A194584-", - "T194585-", - "G194586-", - "T194587-", - "T194588-", - "G194589-", - "T194590-", - "C194591-", - "T194592-", - "A194593-", - "T194594-", - "C194595-", - "G194596-", - "T194597-", - "G194598-", - "T194599-" - ], - "OPG002": [ - "K31X", - "C32-", - "K33-", - "D34-", - "N35-", - "E36-", - "Y37-", - "R38-", - "S39-", - "R40-", - "N41-", - "L42-", - "C43-", - "C44-", - "L45-", - "S46-", - "C47-", - "*350X" - ], - "OPG057": [ - "N267D" - ], - "OPG080": [ - "M1-", - "F2-", - "V3-", - "I4-", - "K5-", - "R6-", - "N7-", - "G8-", - "Y9-", - "K10-", - "E11-", - "N12-", - "V13-", - "M14-", - "F15-", - "D16-", - "K17-", - "I18-", - "T19-", - "S20-", - "R21-", - "I22-", - "R23-", - "K24-", - "L25-", - "C26-", - "Y27-", - "G28-", - "L29-", - "N30-", - "T31-", - "D32-", - "H33-", - "I34-", - "D35-", - "P36-", - "I37-", - "K38-", - "I39-", - "A40-", - "M41-", - "K42-", - "V43-", - "I44-", - "Q45-", - "G46-", - "I47-", - "Y48-", - "N49-", - "G50-", - "V51-", - "T52-", - "T53-", - "V54-", - "E55-", - "L56-", - "D57-", - "T58-", - "L59-", - "A60-", - "A61-", - "E62-", - "I63-", - "A64-", - "A65-", - "T66-", - "C67-", - "T68-", - "L77X", - "A78-", - "*772X" - ], - "OPG081": [ - "X41-", - "S42-", - "L43-", - "K44-", - "F45-", - "X46-", - "I61-", - "P62-", - "G63-", - "T64-", - "I65-", - "I66-", - "L67-", - "Y68-", - "A69-", - "T70-", - "Y71-", - "V72-", - "K73-", - "S74-", - "L75-", - "L76-", - "M77-", - "K78-", - "N79-", - "X80-" - ], - "OPG082": [ - "S255-", - "S256-", - "F257-", - "T258-", - "T259-", - "P260-", - "K261-", - "T262-", - "F263-", - "T264-", - "P265-", - "L266-", - "N267-", - "A268-", - "S269-", - "P270-", - "Y271-", - "I272-", - "P273-", - "K274-", - "X275-" - ], - "OPG083": [ - "I404X", - "N405-", - "V406-", - "I407-", - "C408-" - ], - "OPG089": [ - "S307X", - "Y308-", - "I309X", - "F321X", - "Y335X", - "L336-", - "E337-", - "S338-", - "V339-", - "P340X", - "A348-", - "L349-", - "E350-", - "P351-", - "R352-", - "S358X", - "E359X", - "Y366X", - "D368X", - "F369-", - "E370-", - "N371-", - "T372-", - "K373-", - "S374X", - "F386X", - "G387-", - "Y388-", - "S389-", - "N390-", - "E391-", - "N392-", - "C393-", - "N394-", - "T395-", - "I396-", - "V397-", - "F398-", - "G399-", - "I400-", - "Y401-", - "K402-", - "D403-", - "N404-", - "L405-", - "L406-", - "L407-", - "S408-", - "I409-", - "N416X", - "D417-", - "S418-", - "L419-", - "L420-", - "I421-", - "T422-", - "N423-", - "*435X" - ], - "OPG090": [ - "M1-", - "V2-", - "F3-", - "Q4-", - "L5-", - "V6-", - "C7-", - "S8-", - "T9-", - "C10-", - "G11-", - "K12-", - "D13-", - "I14-", - "S15-", - "H16-", - "E17-", - "R18-", - "Y19-", - "K20-", - "L21-", - "I22-", - "I23-", - "R24-", - "K25-", - "K26-", - "S27-", - "L28-", - "K29-", - "D30-", - "V31-", - "L32-", - "V33-", - "S34-", - "V35-", - "K36-", - "N37-", - "E38-", - "C39-", - "C40-", - "R41-", - "L42-", - "K43-", - "L44-", - "S45-", - "T46-", - "Q47-", - "I48-", - "E49-", - "P50-", - "Q51-", - "R52-", - "N53-", - "L54-", - "T55-", - "V56-", - "Q57-", - "P58-", - "L59-", - "L60-", - "D61-", - "I62-", - "N63-", - "*64-" - ], - "OPG091": [ - "M1-", - "D2-", - "P3-", - "V4-", - "N5-", - "F6-", - "I7-", - "K8-", - "T9-", - "Y10-", - "A11-", - "P12-", - "R13-", - "G14-", - "S15-", - "I16-", - "I17-", - "F18-", - "I19-", - "L44X", - "L45-", - "S46-", - "E47-", - "H48-", - "L49-", - "V50-", - "V51-", - "E52-", - "S53-", - "T54-", - "Y55-", - "R56-", - "K57-", - "G58-", - "V59-", - "R60-", - "I61-", - "V62-", - "P63-", - "L64-", - "D65-", - "R66-", - "F67-", - "F68-", - "E69-", - "G70-", - "Y71-", - "L72-", - "S73-", - "A74-", - "K75-", - "V76-", - "Y77-", - "M78-", - "L79-", - "E80-", - "N81-", - "I82-", - "Q83-", - "V84-", - "M85-", - "K86-", - "I87-", - "A88-", - "A89X", - "F102X", - "G103X", - "K111X", - "L112-", - "V113-", - "A114-", - "E115-", - "C116-", - "Y117-", - "K118-", - "N119-", - "A120-", - "G121-", - "I122-", - "D123-", - "T124-", - "S125-", - "S126-", - "K127-", - "R128-", - "I129-", - "L130-", - "G131-", - "K132-", - "D133-", - "I134-", - "F135-", - "L136-", - "S137-", - "Q138-", - "N139-", - "F140-", - "T141-", - "D142-", - "D143-", - "N144-", - "R145-", - "W146X", - "Y162X", - "*166X" - ], - "OPG092": [ - "A186-", - "G187-", - "F188-", - "S189-", - "G190-", - "K191-", - "E192-", - "P193-", - "I194-", - "S195-", - "N196-", - "Y197-", - "S198-", - "A199-", - "E200-", - "V201-", - "E202-", - "R203-", - "L204-", - "M205-", - "E206-", - "L207-", - "P208-", - "V209-", - "K210-", - "T211-", - "D212-", - "I213-", - "V214-", - "N215-", - "T216-", - "T217-", - "Y218-", - "D219-", - "F220-", - "L221-", - "A222-", - "R223-", - "K224-", - "G225-", - "I226-", - "D227-", - "T228-", - "S229-", - "N230-", - "N231-", - "I232-", - "A233-", - "E234-", - "Y235-", - "I236-", - "A237-", - "G238-", - "L239-", - "K240-", - "I241-", - "E242-", - "E243-", - "I244-", - "E245-", - "K246-", - "V247-", - "E248-", - "K249-", - "Y250-", - "L251-", - "P252-", - "E253-", - "V254-", - "I255-", - "S256-", - "T257-", - "I258-", - "A259-", - "N260-", - "S261-", - "N262-", - "I263-", - "I264-", - "K265-", - "N266-", - "K267-", - "K268-", - "S269-", - "I270-", - "F271-", - "P272-", - "A273-", - "N274-", - "I275-", - "N276-", - "D277-", - "K278-", - "Q279-", - "I280-", - "M281-", - "E282-", - "C283-", - "S284-", - "R285-", - "M286-", - "L287-", - "D288-", - "T289-", - "S290-", - "E291-", - "K292-", - "Y293-", - "S294-", - "K295-", - "G296-", - "Y297-", - "K298-", - "T299-", - "D300-", - "G301-", - "A302-", - "V303-", - "T304-", - "S305-", - "P306-", - "L307-", - "T308-", - "G309-", - "N310-", - "N311-", - "T312-", - "I313-", - "T314-", - "T315-", - "F316-", - "I317-", - "P318-", - "I319-", - "S320-", - "A321-", - "S322-", - "D323-", - "M324-", - "Q325-", - "K326-", - "F327-", - "T328-", - "I329-", - "L330-", - "E331-", - "Y332-", - "L333-", - "Y334-", - "I335-", - "M336-", - "R337-", - "V338-", - "M339-", - "A340-", - "N341-", - "N342-", - "V343-", - "K344-", - "K345-", - "K346-", - "N347X", - "V365X", - "*372X" - ], - "OPG109": [ - "Y18X", - "L19-", - "L20-", - "D21-", - "T22-", - "N23-", - "I24-", - "S25-", - "A75-", - "I76-", - "F77X", - "T94X", - "D100X", - "K101-", - "F116-", - "*796X" - ], - "OPG110": [ - "H23X", - "*211X" - ] - }, - "labels": { - "aa": "OPG002: K31X, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-, C47-, *350X; OPG057: N267D; OPG080: M1-, F2-, V3-, I4-, K5-, R6-, N7-, G8-, Y9-, K10-, E11-, N12-, V13-, M14-, F15-, D16-, K17-, I18-, T19-, S20-, R21-, I22-, R23-, K24-, L25-, C26-, Y27-, G28-, L29-, N30-, T31-, D32-, H33-, I34-, D35-, P36-, I37-, K38-, I39-, A40-, M41-, K42-, V43-, I44-, Q45-, G46-, I47-, Y48-, N49-, G50-, V51-, T52-, T53-, V54-, E55-, L56-, D57-, T58-, L59-, A60-, A61-, E62-, I63-, A64-, A65-, T66-, C67-, T68-, L77X, A78-, *772X; OPG081: X41-, S42-, L43-, K44-, F45-, X46-, I61-, P62-, G63-, T64-, I65-, I66-, L67-, Y68-, A69-, T70-, Y71-, V72-, K73-, S74-, L75-, L76-, M77-, K78-, N79-, X80-; OPG082: S255-, S256-, F257-, T258-, T259-, P260-, K261-, T262-, F263-, T264-, P265-, L266-, N267-, A268-, S269-, P270-, Y271-, I272-, P273-, K274-, X275-; OPG083: I404X, N405-, V406-, I407-, C408-; OPG089: S307X, Y308-, I309X, F321X, Y335X, L336-, E337-, S338-, V339-, P340X, A348-, L349-, E350-, P351-, R352-, S358X, E359X, Y366X, D368X, F369-, E370-, N371-, T372-, K373-, S374X, F386X, G387-, Y388-, S389-, N390-, E391-, N392-, C393-, N394-, T395-, I396-, V397-, F398-, G399-, I400-, Y401-, K402-, D403-, N404-, L405-, L406-, L407-, S408-, I409-, N416X, D417-, S418-, L419-, L420-, I421-, T422-, N423-, *435X; OPG090: M1-, V2-, F3-, Q4-, L5-, V6-, C7-, S8-, T9-, C10-, G11-, K12-, D13-, I14-, S15-, H16-, E17-, R18-, Y19-, K20-, L21-, I22-, I23-, R24-, K25-, K26-, S27-, L28-, K29-, D30-, V31-, L32-, V33-, S34-, V35-, K36-, N37-, E38-, C39-, C40-, R41-, L42-, K43-, L44-, S45-, T46-, Q47-, I48-, E49-, P50-, Q51-, R52-, N53-, L54-, T55-, V56-, Q57-, P58-, L59-, L60-, D61-, I62-, N63-, *64-; OPG091: M1-, D2-, P3-, V4-, N5-, F6-, I7-, K8-, T9-, Y10-, A11-, P12-, R13-, G14-, S15-, I16-, I17-, F18-, I19-, L44X, L45-, S46-, E47-, H48-, L49-, V50-, V51-, E52-, S53-, T54-, Y55-, R56-, K57-, G58-, V59-, R60-, I61-, V62-, P63-, L64-, D65-, R66-, F67-, F68-, E69-, G70-, Y71-, L72-, S73-, A74-, K75-, V76-, Y77-, M78-, L79-, E80-, N81-, I82-, Q83-, V84-, M85-, K86-, I87-, A88-, A89X, F102X, G103X, K111X, L112-, V113-, A114-, E115-, C116-, Y117-, K118-, N119-, A120-, G121-, I122-, D123-, T124-, S125-, S126-, K127-, R128-, I129-, L130-, G131-, K132-, D133-, I134-, F135-, L136-, S137-, Q138-, N139-, F140-, T141-, D142-, D143-, N144-, R145-, W146X, Y162X, *166X; OPG092: A186-, G187-, F188-, S189-, G190-, K191-, E192-, P193-, I194-, S195-, N196-, Y197-, S198-, A199-, E200-, V201-, E202-, R203-, L204-, M205-, E206-, L207-, P208-, V209-, K210-, T211-, D212-, I213-, V214-, N215-, T216-, T217-, Y218-, D219-, F220-, L221-, A222-, R223-, K224-, G225-, I226-, D227-, T228-, S229-, N230-, N231-, I232-, A233-, E234-, Y235-, I236-, A237-, G238-, L239-, K240-, I241-, E242-, E243-, I244-, E245-, K246-, V247-, E248-, K249-, Y250-, L251-, P252-, E253-, V254-, I255-, S256-, T257-, I258-, A259-, N260-, S261-, N262-, I263-, I264-, K265-, N266-, K267-, K268-, S269-, I270-, F271-, P272-, A273-, N274-, I275-, N276-, D277-, K278-, Q279-, I280-, M281-, E282-, C283-, S284-, R285-, M286-, L287-, D288-, T289-, S290-, E291-, K292-, Y293-, S294-, K295-, G296-, Y297-, K298-, T299-, D300-, G301-, A302-, V303-, T304-, S305-, P306-, L307-, T308-, G309-, N310-, N311-, T312-, I313-, T314-, T315-, F316-, I317-, P318-, I319-, S320-, A321-, S322-, D323-, M324-, Q325-, K326-, F327-, T328-, I329-, L330-, E331-, Y332-, L333-, Y334-, I335-, M336-, R337-, V338-, M339-, A340-, N341-, N342-, V343-, K344-, K345-, K346-, N347X, V365X, *372X; OPG109: Y18X, L19-, L20-, D21-, T22-, N23-, I24-, S25-, A75-, I76-, F77X, T94X, D100X, K101-, F116-, *796X; OPG110: H23X, *211X" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000114", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133099-", - "C148268T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - }, - "children": [ - { - "name": "MPXV_IRBA22-11", - "node_attrs": { - "div": 557, - "author": { - "author": "Jarjaval,F., Nolent,F., Criqui,A., Chapus,C., Lamer,O., Ferraris,O., Gorge,O.", - "value": "Jarjaval,F., Nolent,F., Criqui,A., Chapus,C., Lamer,O., Ferraris,O., Gorge,O." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IRBA, D.DNRBC/D.2MI/U.BACT" - }, - "date": { - "value": "2022-05-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV_IRBA22-11" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON755039" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133094-", - "T133095-", - "T133096-", - "T133097-", - "T133098-", - "A173274-", - "T173275-", - "A173276-", - "T173277-" - ] - } - } - }, - { - "name": "NODE_0000115", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.19" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G9963A" - ], - "OPG021": [ - "R126K" - ] - }, - "labels": { - "aa": "OPG021: R126K", - "clade": "B.1.19" - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-4017/2022", - "node_attrs": { - "div": 558, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Griffiths,E., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Griffiths,E., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-07-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.19" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-4017/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP270026" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-133099T", - "-196603A" - ] - } - } - }, - { - "name": "ID6821", - "node_attrs": { - "div": 560, - "author": { - "author": "Viscardi,M., Cozzolino,L., De Martinis,C., Cardillo,L., Fusco,G.", - "value": "Viscardi,M., Cozzolino,L., De Martinis,C., Cardillo,L., Fusco,G." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Istituto Zooprofilattico Sperimentale del Mezzogiorno, Hanimal Health" - }, - "date": { - "value": "2022-06-21" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.19" - }, - "strain_original": { - "value": "ID6821" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP838893" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Italy" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A4728-", - "A4729-", - "C4730-", - "T4731-", - "A4732-", - "A4733-", - "C4734-", - "T4735-", - "T4736-", - "A4737-", - "T4738-", - "G4739-", - "A16614T", - "T29758C", - "T133100-", - "T133101-", - "T133102-", - "C133103-", - "G133104-", - "A133105-", - "A133106-", - "T133107-", - "T133108-", - "C133109-", - "A133110-", - "C133111-", - "G133112T", - "A140105-", - "T140106-", - "A140107-", - "A140108-", - "C140109-", - "A140110-", - "A140111-", - "T140112-", - "T140113-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A157667-", - "A157668-", - "T157669-", - "C157670-", - "A157671-", - "A157672-", - "T157673-", - "G157674-", - "A157675-", - "T157676-", - "A157677-", - "A157678-", - "A157679-", - "A157680-", - "A157681-", - "T157682-", - "T157683-", - "T157684-", - "T157685-", - "T163214-", - "C163215-", - "T163216-", - "T163217-", - "A163218-", - "T163219-", - "A163220-", - "T163221-", - "A163408-", - "A163409-", - "T163410-", - "T163411-", - "C163412-", - "T163413-", - "T163414-", - "C163415-", - "C163416-", - "T169721A", - "G174519-", - "A174520-", - "T174521-", - "G174522-", - "A174523-", - "A174524-", - "G174525-", - "A174526-", - "T174527-", - "G174528-", - "A174529-", - "A174530-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "A180469-", - "A180470-", - "A180471-", - "A180472-", - "A180473-", - "A180474-", - "T180475-", - "T180476-", - "T181102-", - "A181103-", - "T181104-", - "A181105-", - "T181106-", - "T181107-", - "C181108-", - "C181109-", - "T181110-", - "T192477-", - "T192478-", - "A192479-", - "G192480-", - "T192481-", - "T192482-", - "A192483-", - "A192484-", - "G192485-", - "T192486-", - "C192487-", - "A192488-" - ], - "OPG029": [ - "D152E" - ], - "OPG159": [ - "N113X", - "N114-", - "N115-", - "Y116X", - "*146X" - ], - "OPG189": [ - "N26-", - "S27-", - "S28-" - ], - "OPG197": [ - "S18T" - ] - }, - "labels": { - "aa": "OPG029: D152E; OPG159: N113X, N114-, N115-, Y116X, *146X; OPG189: N26-, S27-, S28-; OPG197: S18T" - } - } - }, - { - "name": "NODE_0000116", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.19" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150003A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-" - ] - } - }, - "children": [ - { - "name": "Monkeypox/PT0546/2022", - "node_attrs": { - "div": 564, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-27" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.19" - }, - "strain_original": { - "value": "Monkeypox/PT0546/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555617" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C18602T", - "C74417T", - "C112551T", - "-133099T", - "G174045A", - "C177833T" - ], - "OPG031": [ - "R76K" - ], - "OPG094": [ - "S213L" - ] - }, - "labels": { - "aa": "OPG031: R76K; OPG094: S213L" - } - } - }, - { - "name": "Monkeypox/PT0572/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-09-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.19" - }, - "strain_original": { - "value": "Monkeypox/PT0572/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555643" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C55057T", - "-133099T", - "A169944T", - "C185326T", - "-196603A" - ], - "NBT03_gp052": [ - "E29K" - ], - "OPG197": [ - "E92V" - ], - "OPG210": [ - "S1324L" - ] - }, - "labels": { - "aa": "NBT03_gp052: E29K; OPG197: E92V; OPG210: S1324L" - } - } - }, - { - "name": "MPXV-1047", - "node_attrs": { - "div": 563, - "author": { - "author": "Zeggagh,J., Ferraris,O., Salmona,M., Tarantola,A., Molina,J.M., Delaugerre,C.", - "value": "Zeggagh,J., Ferraris,O., Salmona,M., Tarantola,A., Molina,J.M., Delaugerre,C." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Hopital Saint Louis, Paris" - }, - "date": { - "value": "2022-06-07" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.19" - }, - "strain_original": { - "value": "MPXV-1047" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ172215" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A2591G", - "A31053G", - "T133093-", - "T133094-", - "T133095-", - "T133096-", - "T133097-", - "T133098-", - "-133164C", - "-133165A", - "-133166A", - "-133167T", - "-133168C", - "-133169T", - "-133173T", - "T133633-", - "G150577-", - "A150578-", - "T150579-", - "A150580-", - "T150581-", - "G150582-", - "A150583-", - "T150584-", - "G150620-", - "G150621-", - "A150622-", - "T150623-", - "A150624-", - "T150625-", - "G150626-", - "A150627-", - "T150628-", - "A150629-", - "A152668-", - "T152680-", - "T155897A", - "C173533A", - "A179077T", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "A179140T", - "A179142T", - "A179144T", - "C179145T", - "A179146T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "T194619C", - "T194627G" - ], - "OPG002": [ - "F54S", - "C57G" - ], - "OPG047": [ - "C48R" - ] - }, - "labels": { - "aa": "OPG002: F54S, C57G; OPG047: C48R" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000117", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.16" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C9389T", - "G161797A", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "A185557C" - ], - "OPG188": [ - "E68K" - ], - "OPG210": [ - "K1401T" - ] - }, - "labels": { - "aa": "OPG188: E68K; OPG210: K1401T", - "clade": "B.1.16" - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-24561-E", - "node_attrs": { - "div": 560, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-09-07" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.16" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-24561-E" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP642395" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G161421A" - ], - "OPG187": [ - "R267K" - ] - }, - "labels": { - "aa": "OPG187: R267K" - } - } - }, - { - "name": "NODE_0000118", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.16" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C30154T" - ] - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-23596-O", - "node_attrs": { - "div": 561, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia" - }, - "date": { - "value": "2022-08-29" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.16" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-23596-O" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP459211" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G170076A" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-24909-C", - "node_attrs": { - "div": 561, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-09-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.16" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-24909-C" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP642383" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6863A", - "C132608T" - ] - } - } - }, - { - "name": "DC_INS_MPX_0082_L", - "node_attrs": { - "div": 560, - "author": { - "author": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M.", - "value": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "date": { - "value": "2022-08-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.16" - }, - "strain_original": { - "value": "DC_INS_MPX_0082_L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP693647" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A356-", - "C357-", - "A358-", - "T195509-", - "A195510-", - "A195511-" - ] - } - } - }, - { - "name": "DC_INS_MPX_0719_L", - "node_attrs": { - "div": 561, - "author": { - "author": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M.", - "value": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "date": { - "value": "2022-08-29" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.16" - }, - "strain_original": { - "value": "DC_INS_MPX_0719_L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP693653" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G121275A" - ], - "OPG139": [ - "P32S" - ] - }, - "labels": { - "aa": "OPG139: P32S" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-30512O", - "node_attrs": { - "div": 562, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-11-10" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.16" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-30512O" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ696097" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G23673A", - "G37974A", - "-178536T", - "-178537A", - "-178538T", - "-178539A", - "-178540A", - "-178541G", - "-178542C", - "-178543G", - "-178544G", - "-178545T", - "-178546C", - "-178547G", - "-178548T", - "-178549A", - "-178550C", - "-178551C", - "-178552C", - "-178553A", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-" - ], - "OPG039": [ - "S149L" - ], - "OPG056": [ - "S354L" - ] - }, - "labels": { - "aa": "OPG039: S149L; OPG056: S354L" - } - } - }, - { - "name": "NODE_0000119", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.16" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G148403A", - "-178536T", - "-178537A", - "-178538T", - "-178539A", - "-178540A", - "-178541G", - "-178542C", - "-178543G", - "-178544G", - "-178545T", - "-178546C", - "-178547G", - "-178548T", - "-178549A", - "-178550C", - "-178551C", - "-178552C", - "-178553A" - ] - } - }, - "children": [ - { - "name": "VAC_INS_MPX_0955_C", - "node_attrs": { - "div": 568, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "date": { - "value": "2022-10-11" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.16" - }, - "strain_original": { - "value": "VAC_INS_MPX_0955_C" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP819949" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C18133T", - "G69840A", - "C89599T", - "C117200T", - "G161421A", - "G165412A", - "C178546T" - ], - "OPG187": [ - "R267K" - ], - "OPG190": [ - "M97I" - ] - }, - "labels": { - "aa": "OPG187: R267K; OPG190: M97I" - } - } - }, - { - "name": "VAC_INS_MPX_0960_C", - "node_attrs": { - "div": 563, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "date": { - "value": "2022-10-15" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.16" - }, - "strain_original": { - "value": "VAC_INS_MPX_0960_C" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP819954" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G89896A", - "G164843A" - ], - "OPG110": [ - "E89K" - ], - "OPG189": [ - "G504E" - ] - }, - "labels": { - "aa": "OPG110: E89K; OPG189: G504E" - } - } - }, - { - "name": "LBMB-UTP_MP-021_VAC", - "node_attrs": { - "div": 562, - "author": { - "author": "Anacona,J.D., Lopez,P.A., Orjuela,M., Tabares,F.A., Zuluaga-Velez,A., Sepulveda-Arias,J.C.", - "value": "Anacona,J.D., Lopez,P.A., Orjuela,M., Tabares,F.A., Zuluaga-Velez,A., Sepulveda-Arias,J.C." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud" - }, - "date": { - "value": "2022-11-11" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.16" - }, - "strain_original": { - "value": "LBMB-UTP_MP-021_VAC" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ148473" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133116-", - "A133117-", - "C133118-", - "A133119-", - "A133120-", - "C133121-", - "C133122-", - "G133123-", - "T133124-", - "T133125-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-", - "C188896T" - ] - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000130", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G149818A" - ], - "OPG176": [ - "D4N" - ] - }, - "labels": { - "aa": "OPG176: D4N" - } - }, - "children": [ - { - "name": "MPXV/UZ_REGA_110", - "node_attrs": { - "div": 562, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-10-28" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_110" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035716" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G36963A", - "G48024A", - "C109810T", - "C118161T", - "C170573T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG055": [ - "R41C" - ], - "OPG129": [ - "D399N" - ], - "OPG136": [ - "R476Q" - ], - "OPG198": [ - "S179L" - ] - }, - "labels": { - "aa": "OPG055: R41C; OPG129: D399N; OPG136: R476Q; OPG198: S179L" - } - } - }, - { - "name": "NODE_0000131", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.15" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A11326-", - "T11327-", - "C11328-", - "T11329-", - "A11330-", - "C11331-", - "G11332-", - "A11333-", - "T11334-", - "A11335-", - "T11336-", - "T11337-", - "A11338-", - "G11339-", - "A11340-", - "T11341-", - "A11342-", - "C11343-", - "T11344-", - "T11345-", - "C11346-", - "A11347-", - "C11348-", - "T11349-", - "C11350-", - "A11351-", - "A11352-", - "T11353-", - "G11354-", - "A11355-", - "A11356-", - "T11357-", - "C11358-", - "A11359-", - "A11360-", - "T11361-", - "C11362-", - "A11363-", - "C11364-", - "A11365-", - "C11366-", - "A11367-", - "A11368-", - "T11369-", - "C11370-", - "T11371-", - "A11372-", - "A11373-", - "T11374-", - "G11375-", - "T11376-", - "A11377-", - "G11378-", - "G11379-", - "T11380-", - "T11381-", - "T11382-", - "A11383-", - "T11384-", - "G11385-", - "A11386-", - "C11387-", - "A11388-", - "T11389-", - "A11390-", - "A11391-", - "T11392-", - "A11393-", - "G11394-", - "C11395-", - "A11396-", - "T11397-", - "T11398-", - "T11399-", - "T11400-", - "C11401-", - "A11402-", - "G11403-", - "C11404-", - "A11405-", - "G11406-", - "T11407-", - "T11408-", - "C11409-", - "A11410-", - "A11411-", - "T11412-", - "G11413-", - "T11414-", - "T11415-", - "T11416-", - "C11417-", - "T11418-", - "A11419-", - "G11420-", - "A11421-", - "T11422-", - "T11423-", - "C11424-", - "G11425-", - "T11426-", - "T11427-", - "G11428-", - "A11429-", - "T11430-", - "G11431-", - "G11432-", - "C11433-", - "A11434-", - "A11435-", - "T11436-", - "G11437-", - "G11438-", - "T11439-", - "T11440-", - "A11441-", - "T11442-", - "A11443-", - "C11444-", - "A11445-", - "T11446-", - "G11447-", - "T11448-", - "A11449-", - "T11450-", - "A11451-", - "T11452-", - "C11453-", - "C11454-", - "G11455-", - "T11456-", - "T11457-", - "A11458-", - "T11459-", - "T11460-", - "T11461-", - "G11462-", - "A11463-", - "T11464-", - "C11465-", - "T11466-", - "A11467-", - "A11468-", - "T11469-", - "G11470-", - "T11471-", - "T11472-", - "G11473-", - "A11474-", - "C11475-", - "A11476-", - "T11477-", - "C11478-", - "T11479-", - "G11480-", - "A11481-", - "A11482-", - "C11483-", - "C11484-", - "G11485-", - "G11486-", - "A11487-", - "T11488-", - "T11489-", - "C11490-", - "T11491-", - "A11492-", - "G11493-", - "C11494-", - "A11495-", - "G11496-", - "T11497-", - "A11498-", - "A11499-", - "A11500-", - "G11501-", - "A11502-", - "T11503-", - "A11504-", - "C11505-", - "T11506-", - "A11507-", - "G11508-", - "A11509-", - "G11510-", - "A11511-", - "T11512-", - "T11513-", - "G11514-", - "T11515-", - "T11516-", - "T11517-", - "A11518-", - "T11519-", - "T11520-", - "A11521-", - "T11522-", - "A11523-", - "T11524-", - "C11525-", - "T11526-", - "A11527-", - "A11528-", - "C11529-", - "A11530-", - "G11531-", - "C11532-", - "C11533-", - "T11534-", - "T11535-", - "G11536-", - "T11537-", - "G11538-", - "A11539-", - "A11540-", - "G11541-", - "A11542-", - "A11543-", - "G11544-", - "T11545-", - "G11546-", - "T11547-", - "T11548-", - "T11549-", - "C11550-", - "T11551-", - "C11552-", - "C11553-", - "T11554-", - "C11555-", - "G11556-", - "T11557-", - "T11558-", - "T11559-", - "G11560-", - "T11561-", - "C11562-", - "A11563-", - "A11564-", - "T11565-", - "C11566-", - "A11567-", - "T11568-", - "G11569-", - "T11570-", - "T11571-", - "A11572-", - "A11573-", - "T11574-", - "G11575-", - "T11576-", - "C11577-", - "T11578-", - "T11579-", - "T11580-", - "A11581-", - "A11582-", - "G11583-", - "A11584-", - "T11585-", - "A11586-", - "A11587-", - "G11588-", - "G11589-", - "T11590-", - "A11591-", - "G11592-", - "A11593-", - "C11594-", - "A11595-", - "A11596-", - "A11597-", - "T11598-", - "G11599-", - "T11600-", - "T11601-", - "T11602-", - "A11603-", - "T11604-", - "A11605-", - "G11606-", - "T11607-", - "A11608-", - "C11609-", - "T11610-", - "A11611-", - "A11612-", - "G11613-", - "A11614-", - "A11615-", - "T11616-", - "T11617-", - "G11618-", - "G11619-", - "G11620-", - "C11621-", - "A11622-", - "A11623-", - "A11624-", - "C11625-", - "A11626-", - "T11627-", - "A11628-", - "A11629-", - "G11630-", - "A11631-", - "C11632-", - "A11633-", - "T11634-", - "G11635-", - "T11636-", - "C11637-", - "A11638-", - "C11639-", - "A11640-", - "A11641-", - "A11642-", - "G11643-", - "A11644-", - "C11645-", - "C11646-", - "C11647-", - "T11648-", - "T11649-", - "T11650-", - "T11651-", - "T11652-", - "G11653-", - "T11654-", - "A11655-", - "T11656-", - "G11657-", - "T11658-", - "A11659-", - "T11660-", - "A11661-", - "A11662-", - "G11663-", - "T11664-", - "G11665-", - "T11666-", - "A11667-", - "G11668-", - "A11669-", - "A11670-", - "A11671-", - "T11672-", - "T11673-", - "A11674-", - "T11675-", - "A11676-", - "A11677-", - "C11678-", - "A11679-", - "T11680-", - "C11681-", - "C11682-", - "A11683-", - "T11684-", - "A11685-", - "G11686-", - "T11687-", - "T11688-", - "G11689-", - "G11690-", - "A11691-", - "T11692-", - "T11693-", - "C11694-", - "A11695-", - "C11696-", - "A11697-", - "T11698-", - "A11699-", - "G11700-", - "G11701-", - "T11702-", - "G11703-", - "T11704-", - "C11705-", - "C11706-", - "A11707-", - "A11708-", - "T11709-", - "C11710-", - "G11711-", - "G11712-", - "G11713-", - "A11714-", - "T11715-", - "C11716-", - "T11717-", - "C11718-", - "T11719-", - "C11720-", - "C11721-", - "A11722-", - "T11723-", - "C11724-", - "A11725-", - "T11726-", - "C11727-", - "G11728-", - "A11729-", - "G11730-", - "A11731-", - "T11732-", - "G11733-", - "A11734-", - "T11735-", - "T11736-", - "G11737-", - "A11738-", - "C11739-", - "G11740-", - "G11741-", - "C11742-", - "A11743-", - "T11744-", - "C11745-", - "T11746-", - "C11747-", - "C11748-", - "C11749-", - "C11750-", - "C11751-", - "T11752-", - "T11753-", - "C11754-", - "C11755-", - "T11756-", - "T11757-", - "T11758-", - "T11759-", - "T11760-", - "T11761-", - "A11762-", - "G11763-", - "T11764-", - "A11765-", - "G11766-", - "A11767-", - "T11768-", - "A11769-", - "T11770-", - "T11771-", - "T11772-", - "C11773-", - "A11774-", - "T11775-", - "C11776-", - "G11777-", - "T11778-", - "G11779-", - "T11780-", - "A11781-", - "A11782-", - "G11783-", - "A11784-", - "A11785-", - "T11786-", - "C11787-", - "A11788-", - "A11789-", - "T11790-", - "A11791-", - "T11792-", - "T11793-", - "A11794-", - "A11795-", - "T11796-", - "A11797-", - "T11798-", - "T11799-", - "T11800-", - "C11801-", - "T11802-", - "A11803-", - "A11804-", - "A11805-", - "G11806-", - "T11807-", - "A11808-", - "T11809-", - "C11810-", - "T11811-", - "G11812-", - "T11813-", - "G11814-", - "T11815-", - "A11816-", - "T11817-", - "A11818-", - "G11819-", - "C11820-", - "C11821-", - "T11822-", - "C11823-", - "T11824-", - "T11825-", - "T11826-", - "A11827-", - "T11828-", - "T11829-", - "T11830-", - "A11831-", - "C11832-", - "C11833-", - "A11834-", - "C11835-", - "A11836-", - "G11837-", - "C11838-", - "T11839-", - "C11840-", - "C11841-", - "A11842-", - "T11843-", - "A11844-", - "T11845-", - "T11846-", - "C11847-", - "C11848-", - "A11849-", - "A11850-", - "C11851-", - "A11852-", - "T11853-", - "G11854-", - "C11855-", - "A11856-", - "T11857-", - "T11858-", - "C11859-", - "C11860-", - "A11861-", - "C11862-", - "T11863-", - "A11864-", - "G11865-", - "A11866-", - "G11867-", - "G11868-", - "G11869-", - "A11870-", - "T11871-", - "A11872-", - "T11873-", - "C11874-", - "G11875-", - "A11876-", - "T11877-", - "A11878-", - "T11879-", - "C11880-", - "G11881-", - "C11882-", - "C11883-", - "G11884-", - "A11885-", - "A11886-", - "T11887-", - "G11888-", - "T11889-", - "C11890-", - "A11891-", - "T11892-", - "A11893-", - "T11894-", - "A11895-", - "C11896-", - "T11897-", - "C11898-", - "A11899-", - "A11900-", - "T11901-", - "T11902-", - "A11903-", - "G11904-", - "T11905-", - "A11906-", - "T11907-", - "A11908-", - "T11909-", - "G11910-", - "T11911-", - "T11912-", - "G11913-", - "G11914-", - "A11915-", - "G11916-", - "G11917-", - "A11918-", - "C11919-", - "A11920-", - "T11921-", - "C11922-", - "C11923-", - "G11924-", - "A11925-", - "G11926-", - "T11927-", - "T11928-", - "C11929-", - "A11930-", - "T11931-", - "T11932-", - "G11933-", - "T11934-", - "T11935-", - "T11936-", - "T11937-", - "C11938-", - "A11939-", - "A11940-", - "T11941-", - "A11942-", - "T11943-", - "C11944-", - "A11945-", - "A11946-", - "A11947-", - "G11948-", - "A11949-", - "G11950-", - "A11951-", - "T11952-", - "G11953-", - "G11954-", - "T11955-", - "T11956-", - "T11957-", - "C11958-", - "C11959-", - "T11960-", - "T11961-", - "A11962-", - "T11963-", - "C11964-", - "A11965-", - "T11966-", - "T11967-", - "T11968-", - "C11969-", - "T11970-", - "C11971-", - "C11972-", - "A11973-", - "T11974-", - "A11975-", - "G11976-", - "T11977-", - "G11978-", - "G11979-", - "T11980-", - "A11981-", - "C11982-", - "A11983-", - "A11984-", - "T11985-", - "A11986-", - "C11987-", - "T11988-", - "A11989-", - "C11990-", - "A11991-", - "C11992-", - "A11993-", - "T11994-", - "T11995-", - "A11996-", - "T11997-", - "T11998-", - "C11999-", - "C12000-", - "G12001-", - "T12002-", - "A12003-", - "C12004-", - "G12005-", - "G12006-", - "C12007-", - "T12008-", - "T12009-", - "T12010-", - "C12011-", - "C12012-", - "A12013-", - "T12014-", - "T12015-", - "C12016-", - "T12017-", - "C12018-", - "C12019-", - "A12020-", - "A12021-", - "A12022-", - "A12023-", - "A12024-", - "C12025-", - "A12026-", - "A12027-", - "T12028-", - "T12029-", - "T12030-", - "T12031-", - "A12032-", - "C12033-", - "C12034-", - "A12035-", - "A12036-", - "A12037-", - "T12038-", - "C12039-", - "T12040-", - "A12041-", - "A12042-", - "A12043-", - "T12044-", - "C12045-", - "T12046-", - "A12047-", - "C12048-", - "A12049-", - "T12050-", - "C12051-", - "T12052-", - "T12053-", - "T12054-", - "A12055-", - "T12056-", - "T12057-", - "G12058-", - "T12059-", - "A12060-", - "T12061-", - "C12062-", - "T12063-", - "A12064-", - "T12065-", - "A12066-", - "A12067-", - "T12068-", - "C12069-", - "A12070-", - "C12071-", - "T12072-", - "A12073-", - "T12074-", - "T12075-", - "T12076-", - "A12077-", - "G12078-", - "A12079-", - "T12080-", - "A12081-", - "A12082-", - "T12083-", - "C12084-", - "A12085-", - "G12086-", - "C12087-", - "C12088-", - "A12089-", - "T12090-", - "A12091-", - "A12092-", - "T12093-", - "T12094-", - "C12095-", - "C12096-", - "T12097-", - "C12098-", - "G12099-", - "A12100-", - "G12101-", - "T12102-", - "G12103-", - "C12104-", - "A12105-", - "A12106-", - "C12107-", - "A12108-", - "T12109-", - "G12110-", - "T12111-", - "T12112-", - "A12113-", - "G12114-", - "A12115-", - "T12116-", - "C12117-", - "G12118-", - "T12119-", - "C12120-", - "T12121-", - "A12122-", - "T12123-", - "A12124-", - "T12125-", - "A12126-", - "T12127-", - "G12128-", - "A12129-", - "A12130-", - "T12131-", - "A12132-", - "A12133-", - "G12134-", - "C12135-", - "C12136-", - "G12137-", - "T12138-", - "G12139-", - "T12140-", - "T12141-", - "A12142-", - "T12143-", - "C12144-", - "T12145-", - "A12146-", - "T12147-", - "T12148-", - "C12149-", - "C12150-", - "T12151-", - "T12152-", - "T12153-", - "C12154-", - "A12155-", - "T12156-", - "T12157-", - "A12158-", - "A12159-", - "C12160-", - "A12161-", - "A12162-", - "T12163-", - "T12164-", - "T12165-", - "A12166-", - "A12167-", - "C12168-", - "G12169-", - "A12170-", - "T12171-", - "G12172-", - "T12173-", - "C12174-", - "T12175-", - "A12176-", - "T12177-", - "A12178-", - "T12179-", - "C12180-", - "T12181-", - "A12182-", - "T12183-", - "A12184-", - "T12185-", - "G12186-", - "A12187-", - "G12188-", - "A12189-", - "T12190-", - "G12191-", - "A12192-", - "C12193-", - "T12194-", - "T12195-", - "A12196-", - "A12197-", - "T12198-", - "A12199-", - "T12200-", - "A12201-", - "A12202-", - "T12203-", - "A12204-", - "T12205-", - "T12206-", - "G12207-", - "A12208-", - "A12209-", - "G12210-", - "A12211-", - "G12212-", - "C12213-", - "T12214-", - "G12215-", - "T12216-", - "A12217-", - "C12218-", - "A12219-", - "A12220-", - "T12221-", - "A12222-", - "G12223-", - "T12224-", - "T12225-", - "T12226-", - "T12227-", - "T12228-", - "A12229-", - "T12230-", - "C12231-", - "T12232-", - "A12233-", - "T12234-", - "A12235-", - "G12236-", - "A12237-", - "A12238-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G151362A", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG023": [ - "S221X", - "S222-", - "I223-", - "D224-", - "K225-", - "N226-", - "Y227-", - "C228-", - "T229-", - "A230-", - "L231-", - "Q232-", - "Y233-", - "Y234-", - "I235-", - "K236-", - "S237-", - "S238-", - "H239-", - "I240-", - "D241-", - "I242-", - "D243-", - "I244-", - "V245-", - "K246-", - "L247-", - "L248-", - "M249-", - "K250-", - "G251-", - "I252-", - "D253-", - "N254-", - "T255-", - "A256-", - "Y257-", - "S258-", - "Y259-", - "I260-", - "D261-", - "D262-", - "L263-", - "T264-", - "C265-", - "C266-", - "T267-", - "R268-", - "G269-", - "I270-", - "M271-", - "A272-", - "D273-", - "Y274-", - "L275-", - "N276-", - "S277-", - "D278-", - "Y279-", - "R280-", - "Y281-", - "N282-", - "K283-", - "D284-", - "V285-", - "D286-", - "L287-", - "D288-", - "L289-", - "V290-", - "K291-", - "L292-", - "F293-", - "L294-", - "E295-", - "N296-", - "G297-", - "K298-", - "P299-", - "Y300-", - "G301-", - "I302-", - "M303-", - "C304-", - "S305-", - "I306-", - "V307-", - "P308-", - "L309-", - "W310-", - "R311-", - "N312-", - "D313-", - "K314-", - "E315-", - "T316-", - "I317-", - "S318-", - "L319-", - "I320-", - "L321-", - "K322-", - "T323-", - "M324-", - "N325-", - "S326-", - "D327-", - "V328-", - "L329-", - "Q330-", - "H331-", - "I332-", - "L333-", - "I334-", - "E335-", - "Y336-", - "M337-", - "T338-", - "F339-", - "G340-", - "D341-", - "I342-", - "D343-", - "I344-", - "P345-", - "L346-", - "V347-", - "E348-", - "C349-", - "M350-", - "L351-", - "E352-", - "Y353-", - "G354-", - "A355-", - "V356-", - "V357-", - "N358-", - "K359-", - "E360-", - "A361-", - "I362-", - "H363-", - "R364-", - "Y365-", - "F366-", - "R367-", - "N368-", - "I369-", - "N370-", - "I371-", - "D372-", - "S373-", - "Y374-", - "T375-", - "M376-", - "K377-", - "Y378-", - "L379-", - "L380-", - "K381-", - "K382-", - "E383-", - "G384-", - "G385-", - "D386-", - "A387-", - "V388-", - "N389-", - "H390-", - "L391-", - "D392-", - "D393-", - "G394-", - "E395-", - "I396-", - "P397-", - "I398-", - "G399-", - "H400-", - "L401-", - "C402-", - "E403-", - "S404-", - "N405-", - "Y406-", - "G407-", - "C408-", - "Y409-", - "N410-", - "F411-", - "Y412-", - "T413-", - "Y414-", - "T415-", - "Y416-", - "K417-", - "K418-", - "G419-", - "L420-", - "C421-", - "D422-", - "M423-", - "S424-", - "Y425-", - "V426-", - "C427-", - "P428-", - "I429-", - "L430-", - "S431-", - "T432-", - "I433-", - "N434-", - "I435-", - "C436-", - "L437-", - "P438-", - "Y439-", - "L440-", - "K441-", - "D442-", - "I443-", - "N444-", - "M445-", - "I446-", - "D447-", - "K448-", - "R449-", - "G450-", - "E451-", - "T452-", - "L453-", - "L454-", - "H455-", - "K456-", - "A457-", - "V458-", - "R459-", - "Y460-", - "N461-", - "K462-", - "Q463-", - "S464-", - "L465-", - "V466-", - "S467-", - "L468-", - "L469-", - "L470-", - "E471-", - "S472-", - "G473-", - "S474-", - "D475-", - "V476-", - "N477-", - "I478-", - "R479-", - "S480-", - "N481-", - "N482-", - "G483-", - "Y484-", - "T485-", - "C486-", - "I487-", - "T488-", - "I489-", - "A490-", - "I491-", - "N492-", - "E493-", - "S494-", - "R495-", - "N496-", - "I497-", - "E498-", - "L499-", - "L500-", - "K501-", - "M502-", - "L503-", - "L504-", - "C505-", - "H506-", - "K507-", - "P508-", - "T509-", - "L510-", - "D511-", - "C512-", - "V513-", - "I514-", - "D515-", - "S516-", - "L517-", - "S518-", - "E519-", - "V520-", - "S521-", - "N522-", - "I523-", - "V524-", - "D525-", - "*661X" - ] - }, - "labels": { - "aa": "OPG023: S221X, S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-, *661X", - "clade": "B.1.15" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI018", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Stocker,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Stocker,H., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.15" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI018" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON694335" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A192440-", - "T192441-", - "A192442-", - "A192443-", - "G192444-", - "T192445-", - "T192446-", - "A192447-", - "G192448-", - "T192449-", - "T192450-", - "A192451-", - "A192452-", - "G192453-", - "T192454-", - "C192455-", - "A192456-", - "T192457-", - "A192458-", - "A192459-", - "G192460-", - "T192461-", - "T192462-", - "A192463-", - "G192464-", - "T192465-", - "T192466-", - "A192467-", - "A192468-", - "G192469-", - "T192470-", - "C192471-", - "A196604-" - ] - } - } - }, - { - "name": "Monkeypox/PT0129/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-07-12" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.15" - }, - "strain_original": { - "value": "Monkeypox/PT0129/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP324453" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594A", - "-595T", - "C18133T", - "-196601A", - "-196602A", - "-196603A", - "A196616T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI352", - "node_attrs": { - "div": 561, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.15" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI352" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP484673" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C21128T", - "G74187T", - "C151111T" - ], - "OPG037": [ - "E436K" - ], - "OPG094": [ - "Q136H" - ] - }, - "labels": { - "aa": "OPG037: E436K; OPG094: Q136H" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI561", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.15" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI561" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP764619" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000132", - "node_attrs": { - "div": 563, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.15" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C8385T", - "-11326A", - "-11327T", - "-11328C", - "-11329T", - "-11330A", - "-11331C", - "-11332G", - "-11333A", - "-11334T", - "-11335A", - "-11336T", - "-11337T", - "-11338A", - "-11339G", - "-11340A", - "-11341T", - "-11342A", - "-11343C", - "-11344T", - "-11345T", - "-11346C", - "-11347A", - "-11348C", - "-11349T", - "-11350C", - "-11351A", - "-11352A", - "-11353T", - "-11354G", - "-11355A", - "-11356A", - "-11357T", - "-11358C", - "-11359A", - "-11360A", - "-11361T", - "-11362C", - "-11363A", - "-11364C", - "-11365A", - "-11366C", - "-11367A", - "-11368A", - "-11369T", - "-11370C", - "-11371T", - "-11372A", - "-11373A", - "-11374T", - "-11375G", - "-11376T", - "-11377A", - "-11378G", - "-11379G", - "-11380T", - "-11381T", - "-11382T", - "-11383A", - "-11384T", - "-11385G", - "-11386A", - "-11387C", - "-11388A", - "-11389T", - "-11390A", - "-11391A", - "-11392T", - "-11393A", - "-11394G", - "-11395C", - "-11396A", - "-11397T", - "-11398T", - "-11399T", - "-11400T", - "-11401C", - "-11402A", - "-11403G", - "-11404C", - "-11405A", - "-11406G", - "-11407T", - "-11408T", - "-11409C", - "-11410A", - "-11411A", - "-11412T", - "-11413G", - "-11414T", - "-11415T", - "-11416T", - "-11417C", - "-11418T", - "-11419A", - "-11420G", - "-11421A", - "-11422T", - "-11423T", - "-11424C", - "-11425G", - "-11426T", - "-11427T", - "-11428G", - "-11429A", - "-11430T", - "-11431G", - "-11432G", - "-11433C", - "-11434A", - "-11435A", - "-11436T", - "-11437G", - "-11438G", - "-11439T", - "-11440T", - "-11441A", - "-11442T", - "-11443A", - "-11444C", - "-11445A", - "-11446T", - "-11447G", - "-11448T", - "-11449A", - "-11450T", - "-11451A", - "-11452T", - "-11453C", - "-11454C", - "-11455G", - "-11456T", - "-11457T", - "-11458A", - "-11459T", - "-11460T", - "-11461T", - "-11462G", - "-11463A", - "-11464T", - "-11465C", - "-11466T", - "-11467A", - "-11468A", - "-11469T", - "-11470G", - "-11471T", - "-11472T", - "-11473G", - "-11474A", - "-11475C", - "-11476A", - "-11477T", - "-11478C", - "-11479T", - "-11480G", - "-11481A", - "-11482A", - "-11483C", - "-11484C", - "-11485G", - "-11486G", - "-11487A", - "-11488T", - "-11489T", - "-11490C", - "-11491T", - "-11492A", - "-11493G", - "-11494C", - "-11495A", - "-11496G", - "-11497T", - "-11498A", - "-11499A", - "-11500A", - "-11501G", - "-11502A", - "-11503T", - "-11504A", - "-11505C", - "-11506T", - "-11507A", - "-11508G", - "-11509A", - "-11510G", - "-11511A", - "-11512T", - "-11513T", - "-11514G", - "-11515T", - "-11516T", - "-11517T", - "-11518A", - "-11519T", - "-11520T", - "-11521A", - "-11522T", - "-11523A", - "-11524T", - "-11525C", - "-11526T", - "-11527A", - "-11528A", - "-11529C", - "-11530A", - "-11531G", - "-11532C", - "-11533C", - "-11534T", - "-11535T", - "-11536G", - "-11537T", - "-11538G", - "-11539A", - "-11540A", - "-11541G", - "-11542A", - "-11543A", - "-11544G", - "-11545T", - "-11546G", - "-11547T", - "-11548T", - "-11549T", - "-11550C", - "-11551T", - "-11552C", - "-11553C", - "-11554T", - "-11555C", - "-11556G", - "-11557T", - "-11558T", - "-11559T", - "-11560G", - "-11561T", - "-11562C", - "-11563A", - "-11564A", - "-11565T", - "-11566C", - "-11567A", - "-11568T", - "-11569G", - "-11570T", - "-11571T", - "-11572A", - "-11573A", - "-11574T", - "-11575G", - "-11576T", - "-11577C", - "-11578T", - "-11579T", - "-11580T", - "-11581A", - "-11582A", - "-11583G", - "-11584A", - "-11585T", - "-11586A", - "-11587A", - "-11588G", - "-11589G", - "-11590T", - "-11591A", - "-11592G", - "-11593A", - "-11594C", - "-11595A", - "-11596A", - "-11597A", - "-11598T", - "-11599G", - "-11600T", - "-11601T", - "-11602T", - "-11603A", - "-11604T", - "-11605A", - "-11606G", - "-11607T", - "-11608A", - "-11609C", - "-11610T", - "-11611A", - "-11612A", - "-11613G", - "-11614A", - "-11615A", - "-11616T", - "-11617T", - "-11618G", - "-11619G", - "-11620G", - "-11621C", - "-11622A", - "-11623A", - "-11624A", - "-11625C", - "-11626A", - "-11627T", - "-11628A", - "-11629A", - "-11630G", - "-11631A", - "-11632C", - "-11633A", - "-11634T", - "-11635G", - "-11636T", - "-11637C", - "-11638A", - "-11639C", - "-11640A", - "-11641A", - "-11642A", - "-11643G", - "-11644A", - "-11645C", - "-11646C", - "-11647C", - "-11648T", - "-11649T", - "-11650T", - "-11651T", - "-11652T", - "-11653G", - "-11654T", - "-11655A", - "-11656T", - "-11657G", - "-11658T", - "-11659A", - "-11660T", - "-11661A", - "-11662A", - "-11663G", - "-11664T", - "-11665G", - "-11666T", - "-11667A", - "-11668G", - "-11669A", - "-11670A", - "-11671A", - "-11672T", - "-11673T", - "-11674A", - "-11675T", - "-11676A", - "-11677A", - "-11678C", - "-11679A", - "-11680T", - "-11681C", - "-11682C", - "-11683A", - "-11684T", - "-11685A", - "-11686G", - "-11687T", - "-11688T", - "-11689G", - "-11690G", - "-11691A", - "-11692T", - "-11693T", - "-11694C", - "-11695A", - "-11696C", - "-11697A", - "-11698T", - "-11699A", - "-11700G", - "-11701G", - "-11702T", - "-11703G", - "-11704T", - "-11705C", - "-11706C", - "-11707A", - "-11708A", - "-11709T", - "-11710C", - "-11711G", - "-11712G", - "-11713G", - "-11714A", - "-11715T", - "-11716C", - "-11717T", - "-11718C", - "-11719T", - "-11720C", - "-11721C", - "-11722A", - "-11723T", - "-11724C", - "-11725A", - "-11726T", - "-11727C", - "-11728G", - "-11729A", - "-11730G", - "-11731A", - "-11732T", - "-11733G", - "-11734A", - "-11735T", - "-11736T", - "-11737G", - "-11738A", - "-11739C", - "-11740G", - "-11741G", - "-11742C", - "-11743A", - "-11744T", - "-11745C", - "-11746T", - "-11747C", - "-11748C", - "-11749C", - "-11750C", - "-11751C", - "-11752T", - "-11753T", - "-11754C", - "-11755C", - "-11756T", - "-11757T", - "-11758T", - "-11759T", - "-11760T", - "-11761T", - "-11762A", - "-11763G", - "-11764T", - "-11765A", - "-11766G", - "-11767A", - "-11768T", - "-11769A", - "-11770T", - "-11771T", - "-11772T", - "-11773C", - "-11774A", - "-11775T", - "-11776C", - "-11777G", - "-11778T", - "-11779G", - "-11780T", - "-11781A", - "-11782A", - "-11783G", - "-11784A", - "-11785A", - "-11786T", - "-11787C", - "-11788A", - "-11789A", - "-11790T", - "-11791A", - "-11792T", - "-11793T", - "-11794A", - "-11795A", - "-11796T", - "-11797A", - "-11798T", - "-11799T", - "-11800T", - "-11801C", - "-11802T", - "-11803A", - "-11804A", - "-11805A", - "-11806G", - "-11807T", - "-11808A", - "-11809T", - "-11810C", - "-11811T", - "-11812G", - "-11813T", - "-11814G", - "-11815T", - "-11816A", - "-11817T", - "-11818A", - "-11819G", - "-11820C", - "-11821C", - "-11822T", - "-11823C", - "-11824T", - "-11825T", - "-11826T", - "-11827A", - "-11828T", - "-11829T", - "-11830T", - "-11831A", - "-11832C", - "-11833C", - "-11834A", - "-11835C", - "-11836A", - "-11837G", - "-11838C", - "-11839T", - "-11840C", - "-11841C", - "-11842A", - "-11843T", - "-11844A", - "-11845T", - "-11846T", - "-11847C", - "-11848C", - "-11849A", - "-11850A", - "-11851C", - "-11852A", - "-11853T", - "-11854G", - "-11855C", - "-11856A", - "-11857T", - "-11858T", - "-11859C", - "-11860C", - "-11861A", - "-11862C", - "-11863T", - "-11864A", - "-11865G", - "-11866A", - "-11867G", - "-11868G", - "-11869G", - "-11870A", - "-11871T", - "-11872A", - "-11873T", - "-11874C", - "-11875G", - "-11876A", - "-11877T", - "-11878A", - "-11879T", - "-11880C", - "-11881G", - "-11882C", - "-11883C", - "-11884G", - "-11885A", - "-11886A", - "-11887T", - "-11888G", - "-11889T", - "-11890C", - "-11891A", - "-11892T", - "-11893A", - "-11894T", - "-11895A", - "-11896C", - "-11897T", - "-11898C", - "-11899A", - "-11900A", - "-11901T", - "-11902T", - "-11903A", - "-11904G", - "-11905T", - "-11906A", - "-11907T", - "-11908A", - "-11909T", - "-11910G", - "-11911T", - "-11912T", - "-11913G", - "-11914G", - "-11915A", - "-11916G", - "-11917G", - "-11918A", - "-11919C", - "-11920A", - "-11921T", - "-11922C", - "-11923C", - "-11924G", - "-11925A", - "-11926G", - "-11927T", - "-11928T", - "-11929C", - "-11930A", - "-11931T", - "-11932T", - "-11933G", - "-11934T", - "-11935T", - "-11936T", - "-11937T", - "-11938C", - "-11939A", - "-11940A", - "-11941T", - "-11942A", - "-11943T", - "-11944C", - "-11945A", - "-11946A", - "-11947A", - "-11948G", - "-11949A", - "-11950G", - "-11951A", - "-11952T", - "-11953G", - "-11954G", - "-11955T", - "-11956T", - "-11957T", - "-11958C", - "-11959C", - "-11960T", - "-11961T", - "-11962A", - "-11963T", - "-11964C", - "-11965A", - "-11966T", - "-11967T", - "-11968T", - "-11969C", - "-11970T", - "-11971C", - "-11972C", - "-11973A", - "-11974T", - "-11975A", - "-11976G", - "-11977T", - "-11978G", - "-11979G", - "-11980T", - "-11981A", - "-11982C", - "-11983A", - "-11984A", - "-11985T", - "-11986A", - "-11987C", - "-11988T", - "-11989A", - "-11990C", - "-11991A", - "-11992C", - "-11993A", - "-11994T", - "-11995T", - "-11996A", - "-11997T", - "-11998T", - "-11999C", - "-12000C", - "-12001G", - "-12002T", - "-12003A", - "-12004C", - "-12005G", - "-12006G", - "-12007C", - "-12008T", - "-12009T", - "-12010T", - "-12011C", - "-12012C", - "-12013A", - "-12014T", - "-12015T", - "-12016C", - "-12017T", - "-12018C", - "-12019C", - "-12020A", - "-12021A", - "-12022A", - "-12023A", - "-12024A", - "-12025C", - "-12026A", - "-12027A", - "-12028T", - "-12029T", - "-12030T", - "-12031T", - "-12032A", - "-12033C", - "-12034C", - "-12035A", - "-12036A", - "-12037A", - "-12038T", - "-12039C", - "-12040T", - "-12041A", - "-12042A", - "-12043A", - "-12044T", - "-12045C", - "-12046T", - "-12047A", - "-12048C", - "-12049A", - "-12050T", - "-12051C", - "-12052T", - "-12053T", - "-12054T", - "-12055A", - "-12056T", - "-12057T", - "-12058G", - "-12059T", - "-12060A", - "-12061T", - "-12062C", - "-12063T", - "-12064A", - "-12065T", - "-12066A", - "-12067A", - "-12068T", - "-12069C", - "-12070A", - "-12071C", - "-12072T", - "-12073A", - "-12074T", - "-12075T", - "-12076T", - "-12077A", - "-12078G", - "-12079A", - "-12080T", - "-12081A", - "-12082A", - "-12083T", - "-12084C", - "-12085A", - "-12086G", - "-12087C", - "-12088C", - "-12089A", - "-12090T", - "-12091A", - "-12092A", - "-12093T", - "-12094T", - "-12095C", - "-12096C", - "-12097T", - "-12098C", - "-12099G", - "-12100A", - "-12101G", - "-12102T", - "-12103G", - "-12104C", - "-12105A", - "-12106A", - "-12107C", - "-12108A", - "-12109T", - "-12110G", - "-12111T", - "-12112T", - "-12113A", - "-12114G", - "-12115A", - "-12116T", - "-12117C", - "-12118G", - "-12119T", - "-12120C", - "-12121T", - "-12122A", - "-12123T", - "-12124A", - "-12125T", - "-12126A", - "-12127T", - "-12128G", - "-12129A", - "-12130A", - "-12131T", - "-12132A", - "-12133A", - "-12134G", - "-12135C", - "-12136C", - "-12137G", - "-12138T", - "-12139G", - "-12140T", - "-12141T", - "-12142A", - "-12143T", - "-12144C", - "-12145T", - "-12146A", - "-12147T", - "-12148T", - "-12149C", - "-12150C", - "-12151T", - "-12152T", - "-12153T", - "-12154C", - "-12155A", - "-12156T", - "-12157T", - "-12158A", - "-12159A", - "-12160C", - "-12161A", - "-12162A", - "-12163T", - "-12164T", - "-12165T", - "-12166A", - "-12167A", - "-12168C", - "-12169G", - "-12170A", - "-12171T", - "-12172G", - "-12173T", - "-12174C", - "-12175T", - "-12176A", - "-12177T", - "-12178A", - "-12179T", - "-12180C", - "-12181T", - "-12182A", - "-12183T", - "-12184A", - "-12185T", - "-12186G", - "-12187A", - "-12188G", - "-12189A", - "-12190T", - "-12191G", - "-12192A", - "-12193C", - "-12194T", - "-12195T", - "-12196A", - "-12197A", - "-12198T", - "-12199A", - "-12200T", - "-12201A", - "-12202A", - "-12203T", - "-12204A", - "-12205T", - "-12206T", - "-12207G", - "-12208A", - "-12209A", - "-12210G", - "-12211A", - "-12212G", - "-12213C", - "-12214T", - "-12215G", - "-12216T", - "-12217A", - "-12218C", - "-12219A", - "-12220A", - "-12221T", - "-12222A", - "-12223G", - "-12224T", - "-12225T", - "-12226T", - "-12227T", - "-12228T", - "-12229A", - "-12230T", - "-12231C", - "-12232T", - "-12233A", - "-12234T", - "-12235A", - "-12236G", - "-12237A", - "-12238A", - "G40242A", - "C40335T", - "C127609T", - "G139582A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "T178545-", - "T178548-", - "A178549-", - "A178553-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C" - ], - "OPG023": [ - "X221S", - "-222S", - "-223I", - "-224D", - "-225K", - "-226N", - "-227Y", - "-228C", - "-229T", - "-230A", - "-231L", - "-232Q", - "-233Y", - "-234Y", - "-235I", - "-236K", - "-237S", - "-238S", - "-239H", - "-240I", - "-241D", - "-242I", - "-243D", - "-244I", - "-245V", - "-246K", - "-247L", - "-248L", - "-249M", - "-250K", - "-251G", - "-252I", - "-253D", - "-254N", - "-255T", - "-256A", - "-257Y", - "-258S", - "-259Y", - "-260I", - "-261D", - "-262D", - "-263L", - "-264T", - "-265C", - "-266C", - "-267T", - "-268R", - "-269G", - "-270I", - "-271M", - "-272A", - "-273D", - "-274Y", - "-275L", - "-276N", - "-277S", - "-278D", - "-279Y", - "-280R", - "-281Y", - "-282N", - "-283K", - "-284D", - "-285V", - "-286D", - "-287L", - "-288D", - "-289L", - "-290V", - "-291K", - "-292L", - "-293F", - "-294L", - "-295E", - "-296N", - "-297G", - "-298K", - "-299P", - "-300Y", - "-301G", - "-302I", - "-303M", - "-304C", - "-305S", - "-306I", - "-307V", - "-308P", - "-309L", - "-310W", - "-311R", - "-312N", - "-313D", - "-314K", - "-315E", - "-316T", - "-317I", - "-318S", - "-319L", - "-320I", - "-321L", - "-322K", - "-323T", - "-324M", - "-325N", - "-326S", - "-327D", - "-328V", - "-329L", - "-330Q", - "-331H", - "-332I", - "-333L", - "-334I", - "-335E", - "-336Y", - "-337M", - "-338T", - "-339F", - "-340G", - "-341D", - "-342I", - "-343D", - "-344I", - "-345P", - "-346L", - "-347V", - "-348E", - "-349C", - "-350M", - "-351L", - "-352E", - "-353Y", - "-354G", - "-355A", - "-356V", - "-357V", - "-358N", - "-359K", - "-360E", - "-361A", - "-362I", - "-363H", - "-364R", - "-365Y", - "-366F", - "-367R", - "-368N", - "-369I", - "-370N", - "-371I", - "-372D", - "-373S", - "-374Y", - "-375T", - "-376M", - "-377K", - "-378Y", - "-379L", - "-380L", - "-381K", - "-382K", - "-383E", - "-384G", - "-385G", - "-386D", - "-387A", - "-388V", - "-389N", - "-390H", - "-391L", - "-392D", - "-393D", - "-394G", - "-395E", - "-396I", - "-397P", - "-398I", - "-399G", - "-400H", - "-401L", - "-402C", - "-403E", - "-404S", - "-405N", - "-406Y", - "-407G", - "-408C", - "-409Y", - "-410N", - "-411F", - "-412Y", - "-413T", - "-414Y", - "-415T", - "-416Y", - "-417K", - "-418K", - "-419G", - "-420L", - "-421C", - "-422D", - "-423M", - "-424S", - "-425Y", - "-426V", - "-427C", - "-428P", - "-429I", - "-430L", - "-431S", - "-432T", - "-433I", - "-434N", - "-435I", - "-436C", - "-437L", - "-438P", - "-439Y", - "-440L", - "-441K", - "-442D", - "-443I", - "-444N", - "-445M", - "-446I", - "-447D", - "-448K", - "-449R", - "-450G", - "-451E", - "-452T", - "-453L", - "-454L", - "-455H", - "-456K", - "-457A", - "-458V", - "-459R", - "-460Y", - "-461N", - "-462K", - "-463Q", - "-464S", - "-465L", - "-466V", - "-467S", - "-468L", - "-469L", - "-470L", - "-471E", - "-472S", - "-473G", - "-474S", - "-475D", - "-476V", - "-477N", - "-478I", - "-479R", - "-480S", - "-481N", - "-482N", - "-483G", - "-484Y", - "-485T", - "-486C", - "-487I", - "-488T", - "-489I", - "-490A", - "-491I", - "-492N", - "-493E", - "-494S", - "-495R", - "-496N", - "-497I", - "-498E", - "-499L", - "-500L", - "-501K", - "-502M", - "-503L", - "-504L", - "-505C", - "-506H", - "-507K", - "-508P", - "-509T", - "-510L", - "-511D", - "-512C", - "-513V", - "-514I", - "-515D", - "-516S", - "-517L", - "-518S", - "-519E", - "-520V", - "-521S", - "-522N", - "-523I", - "-524V", - "-525D", - "X661*" - ], - "OPG058": [ - "E34K" - ] - }, - "labels": { - "aa": "OPG023: X221S, -222S, -223I, -224D, -225K, -226N, -227Y, -228C, -229T, -230A, -231L, -232Q, -233Y, -234Y, -235I, -236K, -237S, -238S, -239H, -240I, -241D, -242I, -243D, -244I, -245V, -246K, -247L, -248L, -249M, -250K, -251G, -252I, -253D, -254N, -255T, -256A, -257Y, -258S, -259Y, -260I, -261D, -262D, -263L, -264T, -265C, -266C, -267T, -268R, -269G, -270I, -271M, -272A, -273D, -274Y, -275L, -276N, -277S, -278D, -279Y, -280R, -281Y, -282N, -283K, -284D, -285V, -286D, -287L, -288D, -289L, -290V, -291K, -292L, -293F, -294L, -295E, -296N, -297G, -298K, -299P, -300Y, -301G, -302I, -303M, -304C, -305S, -306I, -307V, -308P, -309L, -310W, -311R, -312N, -313D, -314K, -315E, -316T, -317I, -318S, -319L, -320I, -321L, -322K, -323T, -324M, -325N, -326S, -327D, -328V, -329L, -330Q, -331H, -332I, -333L, -334I, -335E, -336Y, -337M, -338T, -339F, -340G, -341D, -342I, -343D, -344I, -345P, -346L, -347V, -348E, -349C, -350M, -351L, -352E, -353Y, -354G, -355A, -356V, -357V, -358N, -359K, -360E, -361A, -362I, -363H, -364R, -365Y, -366F, -367R, -368N, -369I, -370N, -371I, -372D, -373S, -374Y, -375T, -376M, -377K, -378Y, -379L, -380L, -381K, -382K, -383E, -384G, -385G, -386D, -387A, -388V, -389N, -390H, -391L, -392D, -393D, -394G, -395E, -396I, -397P, -398I, -399G, -400H, -401L, -402C, -403E, -404S, -405N, -406Y, -407G, -408C, -409Y, -410N, -411F, -412Y, -413T, -414Y, -415T, -416Y, -417K, -418K, -419G, -420L, -421C, -422D, -423M, -424S, -425Y, -426V, -427C, -428P, -429I, -430L, -431S, -432T, -433I, -434N, -435I, -436C, -437L, -438P, -439Y, -440L, -441K, -442D, -443I, -444N, -445M, -446I, -447D, -448K, -449R, -450G, -451E, -452T, -453L, -454L, -455H, -456K, -457A, -458V, -459R, -460Y, -461N, -462K, -463Q, -464S, -465L, -466V, -467S, -468L, -469L, -470L, -471E, -472S, -473G, -474S, -475D, -476V, -477N, -478I, -479R, -480S, -481N, -482N, -483G, -484Y, -485T, -486C, -487I, -488T, -489I, -490A, -491I, -492N, -493E, -494S, -495R, -496N, -497I, -498E, -499L, -500L, -501K, -502M, -503L, -504L, -505C, -506H, -507K, -508P, -509T, -510L, -511D, -512C, -513V, -514I, -515D, -516S, -517L, -518S, -519E, -520V, -521S, -522N, -523I, -524V, -525D, X661*; OPG058: E34K" - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-22751-L", - "node_attrs": { - "div": 566, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-08-17" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.15" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-22751-L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP431400" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G47482A", - "C60062T", - "G125388A", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "C178546-", - "G178547-", - "C178550-", - "C178551-", - "C178552-" - ], - "OPG080": [ - "E653K" - ], - "OPG145": [ - "R481H" - ] - }, - "labels": { - "aa": "OPG080: E653K; OPG145: R481H" - } - } - }, - { - "name": "BOL-UNIMOL-MPX-293130-L", - "node_attrs": { - "div": 563, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "date": { - "value": "2022-09-03" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.15" - }, - "strain_original": { - "value": "BOL-UNIMOL-MPX-293130-L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP623590" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A356-", - "C357-", - "A358-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "C178546-", - "G178547-", - "C178550-", - "C178551-", - "C178552-" - ] - } - } - }, - { - "name": "MET_INS_MPX_0956_C", - "node_attrs": { - "div": 565, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "date": { - "value": "2022-10-12" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.15" - }, - "strain_original": { - "value": "MET_INS_MPX_0956_C" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP819950" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G144284A", - "C171808T", - "-178536T", - "-178537A", - "-178538T", - "-178539A", - "-178540A", - "-178545T", - "-178548T", - "-178549A", - "-178553A", - "A196376-", - "T196377-", - "C196378-" - ], - "OPG165": [ - "D257N" - ], - "OPG199": [ - "S274L" - ] - }, - "labels": { - "aa": "OPG165: D257N; OPG199: S274L" - } - } - }, - { - "name": "MPXV/UZ_REGA_163/Belgium/2022", - "node_attrs": { - "div": 568, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-07-27" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.15" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_163/Belgium/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR086972" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G31180A", - "C142626T", - "G158549A", - "G159341A", - "C170750T", - "-178536T", - "-178537A", - "-178538T", - "-178539A", - "-178540A", - "-178545T", - "-178548T", - "-178549A", - "-178553A", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG163": [ - "S142L" - ], - "OPG185": [ - "G142E" - ], - "OPG198": [ - "A238V" - ] - }, - "labels": { - "aa": "OPG163: S142L; OPG185: G142E; OPG198: A238V" - } - } - }, - { - "name": "NODE_0000133", - "node_attrs": { - "div": 564, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.15" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C21324T" - ] - } - }, - "children": [ - { - "name": "BOL-UNIMOL-MPX-293165-L", - "node_attrs": { - "div": 566, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "date": { - "value": "2022-08-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.15" - }, - "strain_original": { - "value": "BOL-UNIMOL-MPX-293165-L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP623592" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C18213T", - "G141921A", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "C178546-", - "G178547-", - "C178550-", - "C178551-", - "C178552-" - ], - "OPG031": [ - "E206K" - ] - }, - "labels": { - "aa": "OPG031: E206K" - } - } - }, - { - "name": "DC_INS_MPX_1024_L", - "node_attrs": { - "div": 567, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "date": { - "value": "2022-09-20" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.15" - }, - "strain_original": { - "value": "DC_INS_MPX_1024_L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP837479" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T509-", - "T510-", - "A511-", - "G68296A", - "C144166T", - "-178536T", - "-178537A", - "-178538T", - "-178539A", - "-178540A", - "-178545T", - "-178548T", - "-178549A", - "-178553A", - "C181495T" - ], - "OPG085": [ - "S79L" - ], - "OPG210": [ - "S47L" - ] - }, - "labels": { - "aa": "OPG085: S79L; OPG210: S47L" - } - } - }, - { - "name": "MPXV/UZ_REGA_115", - "node_attrs": { - "div": 565, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-10-28" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.15" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_115" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035721" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-178536T", - "-178537A", - "-178538T", - "-178539A", - "-178540A", - "-178545T", - "-178548T", - "-178549A", - "-178553A", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "G180556A", - "T195509-", - "A195510-", - "A195511-" - ] - } - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000134", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G175093A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A" - ], - "OPG204": [ - "D188N" - ] - }, - "labels": { - "aa": "OPG204: D188N", - "clade": "B.1.13" - } - }, - "children": [ - { - "name": "MPXV-USA-IL-IDPH-002", - "node_attrs": { - "div": 559, - "author": { - "author": "Gagnon,K.T.", - "value": "Gagnon,K.T." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry" - }, - "date": { - "value": "2022-08-04" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "strain_original": { - "value": "MPXV-USA-IL-IDPH-002" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536663" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "G119424A", - "G125452A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "-196601A", - "-196602A", - "-196603A" - ], - "OPG136": [ - "S55L" - ], - "OPG146": [ - "S63L" - ] - }, - "labels": { - "aa": "OPG136: S55L; OPG146: S63L" - } - } - }, - { - "name": "hMPX/USA/CA-LACPHL-MA00177/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-08-10" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "strain_original": { - "value": "hMPX/USA/CA-LACPHL-MA00177/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP580610" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C55472T", - "G55632A", - "G85638A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "G167713A", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG074": [ - "D552N" - ], - "OPG107": [ - "A43T" - ], - "OPG193": [ - "R127K" - ] - }, - "labels": { - "aa": "OPG074: D552N; OPG107: A43T; OPG193: R127K" - } - } - }, - { - "name": "NODE_0000135", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G22814A", - "G55162A", - "G137128A", - "G167910A", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG038": [ - "H116Y" - ], - "OPG074": [ - "S655L" - ], - "OPG193": [ - "E193K" - ] - }, - "labels": { - "aa": "OPG038: H116Y; OPG074: S655L; OPG193: E193K" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_AZ0003", - "node_attrs": { - "div": 561, - "author": { - "author": "Gigante,C.M., Francis,D., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Escobar,J., Li,Y.", - "value": "Gigante,C.M., Francis,D., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Escobar,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "strain_original": { - "value": "MPXV_USA_2022_AZ0003" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP603009" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C179172-", - "C179181-", - "C179190-", - "C179199-" - ] - } - } - }, - { - "name": "NODE_0000136", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C118921T", - "A173274-", - "T173275-", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A" - ], - "OPG136": [ - "D223N" - ] - }, - "labels": { - "aa": "OPG136: D223N" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_KS0004", - "node_attrs": { - "div": 562, - "author": { - "author": "Gigante,C., Bradley,A., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Sheth,M.R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Anderson,J., Li,Y.", - "value": "Gigante,C., Bradley,A., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Sheth,M.R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Anderson,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-10-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "strain_original": { - "value": "MPXV_USA_2022_KS0004" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ320456" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV_USA_2022_KS0005", - "node_attrs": { - "div": 563, - "author": { - "author": "Gigante,C., Bradley,A., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Anderson,J., Li,Y.", - "value": "Gigante,C., Bradley,A., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Anderson,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "strain_original": { - "value": "MPXV_USA_2022_KS0005" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ721921" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C110297T", - "A173276-", - "T173277-" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000137", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C132520T", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - }, - "children": [ - { - "name": "MpxV/human/USA/OH-UW-073812/2022", - "node_attrs": { - "div": 558, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "strain_original": { - "value": "MpxV/human/USA/OH-UW-073812/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP257254" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV-USA-IL-IDPH-072", - "node_attrs": { - "div": 558, - "author": { - "author": "Gagnon,K.T.", - "value": "Gagnon,K.T." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry" - }, - "date": { - "value": "2022-06-30" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "strain_original": { - "value": "MPXV-USA-IL-IDPH-072" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536733" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "-196601A", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "NY-NYCPHL-000005", - "node_attrs": { - "div": 558, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-07-06" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "strain_original": { - "value": "NY-NYCPHL-000005" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468911" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T150544-", - "A150545-", - "T150546-", - "G150547-", - "A150548-", - "A150549-", - "G150550-", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558A", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "hMpxV/USA/IL-RIPHL-MPXV-052-0034/2023", - "node_attrs": { - "div": 565, - "author": { - "author": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S.", - "value": "Green,S., Kunstman,K., Barbian,H., Araujo Perez,F., Kittner,A., Bobrovska,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)" - }, - "date": { - "value": "2023-05-10" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "strain_original": { - "value": "hMpxV/USA/IL-RIPHL-MPXV-052-0034/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR160418" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C27520T", - "G58883A", - "G99832A", - "G102186A", - "G129583A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G171410A", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-", - "C182950T" - ], - "OPG043": [ - "A146T" - ], - "OPG118": [ - "D463N" - ], - "OPG121": [ - "E133K" - ], - "OPG210": [ - "S532L" - ] - }, - "labels": { - "aa": "OPG043: A146T; OPG118: D463N; OPG121: E133K; OPG210: S532L" - } - } - }, - { - "name": "NODE_0000138", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G165086A", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-" - ] - } - }, - "children": [ - { - "name": "MPXV_USA_2022_KY0001", - "node_attrs": { - "div": 561, - "author": { - "author": "Gigante,C.M., Winter,K., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Arora,V., Li,Y.", - "value": "Gigante,C.M., Winter,K., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Arora,V., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "strain_original": { - "value": "MPXV_USA_2022_KY0001" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP303788" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C43238T", - "G101775A" - ], - "OPG063": [ - "D151N" - ] - }, - "labels": { - "aa": "OPG063: D151N" - } - } - }, - { - "name": "hMpxV/Human/USA/IL-RIPHL-MPXV_10002/2022", - "node_attrs": { - "div": 563, - "author": { - "author": "Barbian,H., Green,S., Kunstman,K., Araujo Perez,F., Bobrovska,S., Hayden,M., Moore,N.", - "value": "Barbian,H., Green,S., Kunstman,K., Araujo Perez,F., Bobrovska,S., Hayden,M., Moore,N." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)" - }, - "date": { - "value": "2022-08-13" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "strain_original": { - "value": "hMpxV/Human/USA/IL-RIPHL-MPXV_10002/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP820451" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C77829T", - "C85055T", - "G142550A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "G165904A", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-" - ], - "OPG163": [ - "D117N" - ] - }, - "labels": { - "aa": "OPG163: D117N" - } - } - } - ] - }, - { - "name": "NODE_0000139", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C21383T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G" - ], - "OPG037": [ - "G351S" - ] - }, - "labels": { - "aa": "OPG037: G351S" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/ON/RKI681", - "node_attrs": { - "div": 561, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI681" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ319139" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C24584T", - "G27462A", - "G150550-", - "A152668-", - "T152680-", - "T178896-", - "T178897-", - "A178898-", - "C178899-", - "A178900-", - "A178901-", - "G178902-", - "A178903-", - "T178904-", - "A178905-", - "C178906-", - "A178907-", - "T178908-", - "T178909-", - "T178910-", - "A178911-", - "A178912-", - "T178913-", - "G178914-", - "T178915-", - "G178916-", - "C178917-", - "T178918-", - "T178919-", - "A178920-", - "C178921-", - "G178922-", - "G178923-", - "A178924-", - "A178925-", - "C178926-", - "A178927-", - "T178928-", - "A178929-", - "T178930-", - "A178931-", - "T178932-", - "T178933-", - "T178934-", - "A178935-", - "G178936-", - "A178937-", - "A178938-", - "A178939-", - "C178940-", - "A178941-", - "T178942-", - "C178943-", - "T178944-", - "A178945-", - "C178946-", - "T178947-", - "A178948-", - "A178949-", - "C178950-", - "G178951-", - "A178952-", - "T178953-", - "T178954-", - "T178955-", - "T178956-", - "T178957-", - "T178958-", - "A178959-", - "T178960-", - "G178961-", - "C178962-", - "T178963-", - "T178964-", - "G178965-", - "T178966-", - "A178967-" - ], - "OPG040": [ - "D299N" - ], - "OPG043": [ - "S165L" - ] - }, - "labels": { - "aa": "OPG040: D299N; OPG043: S165L" - } - } - }, - { - "name": "NODE_0000140", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G85431A", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG106": [ - "S23F" - ] - }, - "labels": { - "aa": "OPG106: S23F" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI287", - "node_attrs": { - "div": 561, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Friesen,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Friesen,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI287" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP270476" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C172851T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI901", - "node_attrs": { - "div": 562, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.13" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI901" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773520" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C146446T", - "C147140T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ], - "OPG170": [ - "M111I" - ] - }, - "labels": { - "aa": "OPG170: M111I" - } - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000141", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G12169A", - "G44960A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - }, - "labels": { - "clade": "B.1.17" - } - }, - "children": [ - { - "name": "hMPX/Human/USA/CA-LACPHL-MA00051/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Hemarajata,P., Green,N.M.", - "value": "Hemarajata,P., Green,N.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-07-20" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "strain_original": { - "value": "hMPX/Human/USA/CA-LACPHL-MA00051/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP440533" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C60079T" - ], - "OPG080": [ - "R647K" - ] - }, - "labels": { - "aa": "OPG080: R647K" - } - } - }, - { - "name": "hMPX/Human/USA/CA-LACPHL-MA00078/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-08-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "strain_original": { - "value": "hMPX/Human/USA/CA-LACPHL-MA00078/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP442539" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150567T", - "C172851T" - ] - } - } - }, - { - "name": "hMPX/Human/USA/CA-LACPHL-MA00085/2022", - "node_attrs": { - "div": 558, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-07-13" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "strain_original": { - "value": "hMPX/Human/USA/CA-LACPHL-MA00085/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP442552" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G472-", - "A473-", - "T474-", - "A196429-", - "G196430-", - "A196431-" - ] - } - } - }, - { - "name": "MPX/Human/USA/CA-LACPHL-MA00120/2022", - "node_attrs": { - "div": 558, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-08-29" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "strain_original": { - "value": "MPX/Human/USA/CA-LACPHL-MA00120/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP539905" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "hMPX/USA/CA-LACPHL-MA00168/2022", - "node_attrs": { - "div": 558, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-09-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "strain_original": { - "value": "hMPX/USA/CA-LACPHL-MA00168/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP580601" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G520-", - "A521-", - "A522-" - ] - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-084166/2022", - "node_attrs": { - "div": 563, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-084166/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP628456" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A11836G", - "C12850T", - "G69249A", - "C113363T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "G171959A", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179154C", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C" - ], - "OPG132": [ - "D60N" - ] - }, - "labels": { - "aa": "OPG132: D60N" - } - } - }, - { - "name": "MPXV_USA_2022_CA0029", - "node_attrs": { - "div": 558, - "author": { - "author": "Gigante,C., Ventura,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nash,J., Li,Y.", - "value": "Gigante,C., Ventura,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nash,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "strain_original": { - "value": "MPXV_USA_2022_CA0029" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ054244" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A136513-", - "T136514-", - "C136515-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "A173274-", - "T173275-", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179154C", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "NODE_0000142", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A39081T", - "-150567T" - ], - "OPG057": [ - "I372N" - ] - }, - "labels": { - "aa": "OPG057: I372N" - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00330/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-11-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00330/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP890558" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T39065-", - "T39066-", - "T39067-", - "T39068-", - "T39069-", - "A39070-", - "A39071-", - "T39072-", - "T39073-" - ] - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00313/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-11-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00313/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP890570" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G178111A", - "A196429-", - "G196430-", - "A196431-" - ] - } - } - } - ] - }, - { - "name": "NODE_0000143", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150567T", - "G155611A" - ] - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00348/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-10-06" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00348/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP920686" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00455/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-10-14" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00455/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503789" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000144", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T39394-", - "A39395-", - "T39396-", - "C85931T", - "-150567T" - ], - "OPG057": [ - "N267X", - "R268X", - "*373X" - ] - }, - "labels": { - "aa": "OPG057: N267X, R268X, *373X" - } - }, - "children": [ - { - "name": "Monkeypox virus/Human/USA/CA-LACPHL-MA00391/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-12-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "strain_original": { - "value": "Monkeypox virus/Human/USA/CA-LACPHL-MA00391/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ330999" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C174129T" - ] - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00423/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-12-02" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00423/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503816" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "NODE_0000145", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G71249A", - "G182189A" - ], - "OPG090": [ - "R24Q" - ] - }, - "labels": { - "aa": "OPG090: R24Q" - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00403/2023", - "node_attrs": { - "div": 562, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2023-01-06" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00403/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503826" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G172895A" - ] - } - } - }, - { - "name": "OQ991943", - "node_attrs": { - "div": 561, - "author": { - "author": "Kath,C., Haw,M., Espinosa,A., Hacker,J.", - "value": "Kath,C., Haw,M., Espinosa,A., Hacker,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "date": { - "value": "2023-01-13" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.17" - }, - "strain_original": { - "value": "OQ991943" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ991943" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000146", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G111029A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - }, - "labels": { - "clade": "B.1.6" - } - }, - "children": [ - { - "name": "LIM-INS-001", - "node_attrs": { - "div": 557, - "author": { - "author": "Silva,I., Jimenez,V., Hurtado,V., Barcena,L.", - "value": "Silva,I., Jimenez,V., Hurtado,V., Barcena,L." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular" - }, - "date": { - "value": "2022-06-25" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - }, - "strain_original": { - "value": "LIM-INS-001" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP289782" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Peru" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "-196601A", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "LIM-INS-003", - "node_attrs": { - "div": 557, - "author": { - "author": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Mestanza,O., Lope,P., Nunez,A.", - "value": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Mestanza,O., Lope,P., Nunez,A." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular" - }, - "date": { - "value": "2022-06-27" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - }, - "strain_original": { - "value": "LIM-INS-003" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP289783" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Peru" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "LIM-INS-010", - "node_attrs": { - "div": 557, - "author": { - "author": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Lope,P., Arotinco,G.", - "value": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Lope,P., Arotinco,G." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular" - }, - "date": { - "value": "2022-07-02" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - }, - "strain_original": { - "value": "LIM-INS-010" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP320549" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Peru" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "LIM-INS-013", - "node_attrs": { - "div": 557, - "author": { - "author": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Lope,P., Arotinco,G.", - "value": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Lope,P., Arotinco,G." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular" - }, - "date": { - "value": "2022-07-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - }, - "strain_original": { - "value": "LIM-INS-013" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP320553" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Peru" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "LIM-INS-016", - "node_attrs": { - "div": 559, - "author": { - "author": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Lope,P., Arotinco,G.", - "value": "Padilla,C., Silva,I., Hurtado,V., Jimenez,V., Barcena,L., Lope,P., Arotinco,G." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular" - }, - "date": { - "value": "2022-07-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - }, - "strain_original": { - "value": "LIM-INS-016" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP320554" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Peru" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G25098A", - "A34289G" - ] - } - } - }, - { - "name": "MPX_3U0idu_9000254", - "node_attrs": { - "div": 557, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - }, - "strain_original": { - "value": "MPX_3U0idu_9000254" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415224" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-22752-O", - "node_attrs": { - "div": 558, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-08-18" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-22752-O" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP431402" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G15814A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "9000387", - "node_attrs": { - "div": 559, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - }, - "strain_original": { - "value": "9000387" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536765" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G59112A", - "C87978T" - ] - } - } - }, - { - "name": "DC_INS_MPX-1122-H", - "node_attrs": { - "div": 558, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Rosales,A., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Rosales,A., Mercado-Reyes,M.M." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "date": { - "value": "2022-10-22" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - }, - "strain_original": { - "value": "DC_INS_MPX-1122-H" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ197863" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G544-", - "G545-", - "T546-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "C151204T", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-28353C", - "node_attrs": { - "div": 557, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-10-14" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-28353C" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ261706" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-", - "T195509-", - "A195510-", - "A195511-" - ] - } - } - }, - { - "name": "hMpxV/USA/CA-CDPH-1MPX1000120/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "date": { - "value": "2022-09-20" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - }, - "strain_original": { - "value": "hMpxV/USA/CA-CDPH-1MPX1000120/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ348868" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150364A", - "C166930T" - ], - "OPG176": [ - "E186K" - ], - "OPG192": [ - "S67L" - ] - }, - "labels": { - "aa": "OPG176: E186K; OPG192: S67L" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00422/2022", - "node_attrs": { - "div": 565, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-12-03" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00422/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503815" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C14098T", - "C84063T", - "G97749A", - "G142493A", - "G151324A", - "C170573T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "C187332T", - "G188726A" - ], - "OPG163": [ - "D98N" - ], - "OPG198": [ - "S179L" - ] - }, - "labels": { - "aa": "OPG163: D98N; OPG198: S179L" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00408/2023", - "node_attrs": { - "div": 561, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2023-01-11" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00408/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503831" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G10945A", - "G39515A", - "C44627T", - "G56276A", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-", - "A196604-" - ], - "OPG064": [ - "M424I" - ] - }, - "labels": { - "aa": "OPG064: M424I" - } - } - }, - { - "name": "NODE_0000147", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G132863A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-" - ] - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-24725-L", - "node_attrs": { - "div": 560, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-09-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-24725-L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP642380" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C7396T", - "C29887T", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "LBMB-UTP_MP-004_TOL", - "node_attrs": { - "div": 560, - "author": { - "author": "Orjuela,M., Tabares,F.A., Anacona,J.D., Lopez,P.A., Zuluaga-Velez,A., Sepulveda-Arias,J.C.", - "value": "Orjuela,M., Tabares,F.A., Anacona,J.D., Lopez,P.A., Zuluaga-Velez,A., Sepulveda-Arias,J.C." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud" - }, - "date": { - "value": "2022-09-21" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - }, - "strain_original": { - "value": "LBMB-UTP_MP-004_TOL" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ148463" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G22646A", - "C85452T" - ], - "OPG038": [ - "P172S" - ], - "OPG106": [ - "G16E" - ] - }, - "labels": { - "aa": "OPG038: P172S; OPG106: G16E" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-30518C", - "node_attrs": { - "div": 561, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-11-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.6" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-30518C" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ696099" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G63811A", - "G167862A", - "C170130T" - ], - "OPG193": [ - "D177N" - ] - }, - "labels": { - "aa": "OPG193: D177N" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000148", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "G181367A", - "A196604-" - ] - }, - "labels": { - "clade": "B.1.9" - } - }, - "children": [ - { - "name": "Monkeypox/PT0043/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-05-30" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "strain_original": { - "value": "Monkeypox/PT0043/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON843175" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0394/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-07-13" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "strain_original": { - "value": "Monkeypox/PT0394/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555490" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-196603A", - "-196604A" - ] - } - } - }, - { - "name": "DC_INS_MPX_0718_L", - "node_attrs": { - "div": 558, - "author": { - "author": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M.", - "value": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "date": { - "value": "2022-08-16" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "strain_original": { - "value": "DC_INS_MPX_0718_L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP693652" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-596T", - "G134122T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C" - ] - } - } - }, - { - "name": "NODE_0000149", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C101868T", - "C103427T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C" - ], - "OPG121": [ - "P27S" - ] - }, - "labels": { - "aa": "OPG121: P27S" - } - }, - "children": [ - { - "name": "NY-NYCPHL-000330", - "node_attrs": { - "div": 561, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-08-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "strain_original": { - "value": "NY-NYCPHL-000330" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468869" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G107496A", - "G173727A", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "NODE_0000150", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G61329A" - ] - } - }, - "children": [ - { - "name": "MPXV_USA_2022_NJ0005", - "node_attrs": { - "div": 560, - "author": { - "author": "Gigante,C.M., Acheampong,E., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Morrison,S.S., Seabolt,M.H., Weigand,M.R., Knipe,K., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., McDermott,D., Li,Y.", - "value": "Gigante,C.M., Acheampong,E., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Morrison,S.S., Seabolt,M.H., Weigand,M.R., Knipe,K., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., McDermott,D., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "strain_original": { - "value": "MPXV_USA_2022_NJ0005" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP687938" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NY-NYCPHL-000422", - "node_attrs": { - "div": 561, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-09-07" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "strain_original": { - "value": "NY-NYCPHL-000422" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ419012" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T39394-", - "A39395-", - "T39396-", - "A49374G", - "T50371-", - "C50372-", - "T50373-", - "C50374-", - "T50375-", - "A50376-", - "C50377-", - "C50378-", - "C50379-", - "T50380-", - "A50381-", - "A50382-", - "A50383-", - "C50384-", - "T50385-", - "T50386-", - "T50387-", - "A50388-", - "A50389-", - "C50390-", - "A50391-", - "A50392-", - "T150544-", - "A150545-", - "T150546-", - "G150547-", - "A150548-", - "A150549-", - "G150550-", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558A", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG057": [ - "N267X", - "R268X", - "*373X" - ], - "OPG068": [ - "N392D" - ], - "OPG069": [ - "L129X", - "S130-", - "T131-", - "L132-", - "N133-", - "F134-", - "N135-", - "N136X", - "*167X" - ] - }, - "labels": { - "aa": "OPG057: N267X, R268X, *373X; OPG068: N392D; OPG069: L129X, S130-, T131-, L132-, N133-, F134-, N135-, N136X, *167X" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000151", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G176823A" - ], - "OPG205": [ - "E390K" - ] - }, - "labels": { - "aa": "OPG205: E390K" - } - }, - "children": [ - { - "name": "Monkeypox/PT0005/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Ferreira,R., Sobral,D., Nunes,A., Santos,J.D., Mixao,V., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Ferreira,R., Sobral,D., Nunes,A., Santos,J.D., Mixao,V., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal" - }, - "date": { - "value": "2022-05-15" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "strain_original": { - "value": "Monkeypox/PT0005/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON585037" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-596T", - "A11326-", - "T11327-", - "C11328-", - "T11329-", - "A11330-", - "C11331-", - "G11332-", - "A11333-", - "T11334-", - "A11335-", - "T11336-", - "T11337-", - "A11338-", - "G11339-", - "A11340-", - "T11341-", - "A11342-", - "C11343-", - "T11344-", - "T11345-", - "C11346-", - "A11347-", - "C11348-", - "T11349-", - "C11350-", - "A11351-", - "A11352-", - "T11353-", - "G11354-", - "A11355-", - "A11356-", - "T11357-", - "C11358-", - "A11359-", - "A11360-", - "T11361-", - "C11362-", - "A11363-", - "C11364-", - "A11365-", - "C11366-", - "A11367-", - "A11368-", - "T11369-", - "C11370-", - "T11371-", - "A11372-", - "A11373-", - "T11374-", - "G11375-", - "T11376-", - "A11377-", - "G11378-", - "G11379-", - "T11380-", - "T11381-", - "T11382-", - "A11383-", - "T11384-", - "G11385-", - "A11386-", - "C11387-", - "A11388-", - "T11389-", - "A11390-", - "A11391-", - "T11392-", - "A11393-", - "G11394-", - "C11395-", - "A11396-", - "T11397-", - "T11398-", - "T11399-", - "T11400-", - "C11401-", - "A11402-", - "G11403-", - "C11404-", - "A11405-", - "G11406-", - "T11407-", - "T11408-", - "C11409-", - "A11410-", - "A11411-", - "T11412-", - "G11413-", - "T11414-", - "T11415-", - "T11416-", - "C11417-", - "T11418-", - "A11419-", - "G11420-", - "A11421-", - "T11422-", - "T11423-", - "C11424-", - "G11425-", - "T11426-", - "T11427-", - "G11428-", - "A11429-", - "T11430-", - "G11431-", - "G11432-", - "C11433-", - "A11434-", - "A11435-", - "T11436-", - "G11437-", - "G11438-", - "T11439-", - "T11440-", - "A11441-", - "T11442-", - "A11443-", - "C11444-", - "A11445-", - "T11446-", - "G11447-", - "T11448-", - "A11449-", - "T11450-", - "A11451-", - "T11452-", - "C11453-", - "C11454-", - "G11455-", - "T11456-", - "T11457-", - "A11458-", - "T11459-", - "T11460-", - "T11461-", - "G11462-", - "A11463-", - "T11464-", - "C11465-", - "T11466-", - "A11467-", - "A11468-", - "T11469-", - "G11470-", - "T11471-", - "T11472-", - "G11473-", - "A11474-", - "C11475-", - "A11476-", - "T11477-", - "C11478-", - "T11479-", - "G11480-", - "A11481-", - "A11482-", - "C11483-", - "C11484-", - "G11485-", - "G11486-", - "A11487-", - "T11488-", - "T11489-", - "C11490-", - "T11491-", - "A11492-", - "G11493-", - "C11494-", - "A11495-", - "G11496-", - "T11497-", - "A11498-", - "A11499-", - "A11500-", - "G11501-", - "A11502-", - "T11503-", - "A11504-", - "C11505-", - "T11506-", - "A11507-", - "G11508-", - "A11509-", - "G11510-", - "A11511-", - "T11512-", - "T11513-", - "G11514-", - "T11515-", - "T11516-", - "T11517-", - "A11518-", - "T11519-", - "T11520-", - "A11521-", - "T11522-", - "A11523-", - "T11524-", - "C11525-", - "T11526-", - "A11527-", - "A11528-", - "C11529-", - "A11530-", - "G11531-", - "C11532-", - "C11533-", - "T11534-", - "T11535-", - "G11536-", - "T11537-", - "G11538-", - "A11539-", - "A11540-", - "G11541-", - "A11542-", - "A11543-", - "G11544-", - "T11545-", - "G11546-", - "T11547-", - "T11548-", - "T11549-", - "C11550-", - "T11551-", - "C11552-", - "C11553-", - "T11554-", - "C11555-", - "G11556-", - "T11557-", - "T11558-", - "T11559-", - "G11560-", - "T11561-", - "C11562-", - "A11563-", - "A11564-", - "T11565-", - "C11566-", - "A11567-", - "T11568-", - "G11569-", - "T11570-", - "T11571-", - "A11572-", - "A11573-", - "T11574-", - "G11575-", - "T11576-", - "C11577-", - "T11578-", - "T11579-", - "T11580-", - "A11581-", - "A11582-", - "G11583-", - "A11584-", - "T11585-", - "A11586-", - "A11587-", - "G11588-", - "G11589-", - "T11590-", - "A11591-", - "G11592-", - "A11593-", - "C11594-", - "A11595-", - "A11596-", - "A11597-", - "T11598-", - "G11599-", - "T11600-", - "T11601-", - "T11602-", - "A11603-", - "T11604-", - "A11605-", - "G11606-", - "T11607-", - "A11608-", - "C11609-", - "T11610-", - "A11611-", - "A11612-", - "G11613-", - "A11614-", - "A11615-", - "T11616-", - "T11617-", - "G11618-", - "G11619-", - "G11620-", - "C11621-", - "A11622-", - "A11623-", - "A11624-", - "C11625-", - "A11626-", - "T11627-", - "A11628-", - "A11629-", - "G11630-", - "A11631-", - "C11632-", - "A11633-", - "T11634-", - "G11635-", - "T11636-", - "C11637-", - "A11638-", - "C11639-", - "A11640-", - "A11641-", - "A11642-", - "G11643-", - "A11644-", - "C11645-", - "C11646-", - "C11647-", - "T11648-", - "T11649-", - "T11650-", - "T11651-", - "T11652-", - "G11653-", - "T11654-", - "A11655-", - "T11656-", - "G11657-", - "T11658-", - "A11659-", - "T11660-", - "A11661-", - "A11662-", - "G11663-", - "T11664-", - "G11665-", - "T11666-", - "A11667-", - "G11668-", - "A11669-", - "A11670-", - "A11671-", - "T11672-", - "T11673-", - "A11674-", - "T11675-", - "A11676-", - "A11677-", - "C11678-", - "A11679-", - "T11680-", - "C11681-", - "C11682-", - "A11683-", - "T11684-", - "A11685-", - "G11686-", - "T11687-", - "T11688-", - "G11689-", - "G11690-", - "A11691-", - "T11692-", - "T11693-", - "C11694-", - "A11695-", - "C11696-", - "A11697-", - "T11698-", - "A11699-", - "G11700-", - "G11701-", - "T11702-", - "G11703-", - "T11704-", - "C11705-", - "C11706-", - "A11707-", - "A11708-", - "T11709-", - "C11710-", - "G11711-", - "G11712-", - "G11713-", - "A11714-", - "T11715-", - "C11716-", - "T11717-", - "C11718-", - "T11719-", - "C11720-", - "C11721-", - "A11722-", - "T11723-", - "C11724-", - "A11725-", - "T11726-", - "C11727-", - "G11728-", - "A11729-", - "G11730-", - "A11731-", - "T11732-", - "G11733-", - "A11734-", - "T11735-", - "T11736-", - "G11737-", - "A11738-", - "C11739-", - "G11740-", - "G11741-", - "C11742-", - "A11743-", - "T11744-", - "C11745-", - "T11746-", - "C11747-", - "C11748-", - "C11749-", - "C11750-", - "C11751-", - "T11752-", - "T11753-", - "C11754-", - "C11755-", - "T11756-", - "T11757-", - "T11758-", - "T11759-", - "T11760-", - "T11761-", - "A11762-", - "G11763-", - "T11764-", - "A11765-", - "G11766-", - "A11767-", - "T11768-", - "A11769-", - "T11770-", - "T11771-", - "T11772-", - "C11773-", - "A11774-", - "T11775-", - "C11776-", - "G11777-", - "T11778-", - "G11779-", - "T11780-", - "A11781-", - "A11782-", - "G11783-", - "A11784-", - "A11785-", - "T11786-", - "C11787-", - "A11788-", - "A11789-", - "T11790-", - "A11791-", - "T11792-", - "T11793-", - "A11794-", - "A11795-", - "T11796-", - "A11797-", - "T11798-", - "T11799-", - "T11800-", - "C11801-", - "T11802-", - "A11803-", - "A11804-", - "A11805-", - "G11806-", - "T11807-", - "A11808-", - "T11809-", - "C11810-", - "T11811-", - "G11812-", - "T11813-", - "G11814-", - "T11815-", - "A11816-", - "T11817-", - "A11818-", - "G11819-", - "C11820-", - "C11821-", - "T11822-", - "C11823-", - "T11824-", - "T11825-", - "T11826-", - "A11827-", - "T11828-", - "T11829-", - "T11830-", - "A11831-", - "C11832-", - "C11833-", - "A11834-", - "C11835-", - "A11836-", - "G11837-", - "C11838-", - "T11839-", - "C11840-", - "C11841-", - "A11842-", - "T11843-", - "A11844-", - "T11845-", - "T11846-", - "C11847-", - "C11848-", - "A11849-", - "A11850-", - "C11851-", - "A11852-", - "T11853-", - "G11854-", - "C11855-", - "A11856-", - "T11857-", - "T11858-", - "C11859-", - "C11860-", - "A11861-", - "C11862-", - "T11863-", - "A11864-", - "G11865-", - "A11866-", - "G11867-", - "G11868-", - "G11869-", - "A11870-", - "T11871-", - "A11872-", - "T11873-", - "C11874-", - "G11875-", - "A11876-", - "T11877-", - "A11878-", - "T11879-", - "C11880-", - "G11881-", - "C11882-", - "C11883-", - "G11884-", - "A11885-", - "A11886-", - "T11887-", - "G11888-", - "T11889-", - "C11890-", - "A11891-", - "T11892-", - "A11893-", - "T11894-", - "A11895-", - "C11896-", - "T11897-", - "C11898-", - "A11899-", - "A11900-", - "T11901-", - "T11902-", - "A11903-", - "G11904-", - "T11905-", - "A11906-", - "T11907-", - "A11908-", - "T11909-", - "G11910-", - "T11911-", - "T11912-", - "G11913-", - "G11914-", - "A11915-", - "G11916-", - "G11917-", - "A11918-", - "C11919-", - "A11920-", - "T11921-", - "C11922-", - "C11923-", - "G11924-", - "A11925-", - "G11926-", - "T11927-", - "T11928-", - "C11929-", - "A11930-", - "T11931-", - "T11932-", - "G11933-", - "T11934-", - "T11935-", - "T11936-", - "T11937-", - "C11938-", - "A11939-", - "A11940-", - "T11941-", - "A11942-", - "T11943-", - "C11944-", - "A11945-", - "A11946-", - "A11947-", - "G11948-", - "A11949-", - "G11950-", - "A11951-", - "T11952-", - "G11953-", - "G11954-", - "T11955-", - "T11956-", - "T11957-", - "C11958-", - "C11959-", - "T11960-", - "T11961-", - "A11962-", - "T11963-", - "C11964-", - "A11965-", - "T11966-", - "T11967-", - "T11968-", - "C11969-", - "T11970-", - "C11971-", - "C11972-", - "A11973-", - "T11974-", - "A11975-", - "G11976-", - "T11977-", - "G11978-", - "G11979-", - "T11980-", - "A11981-", - "C11982-", - "A11983-", - "A11984-", - "T11985-", - "A11986-", - "C11987-", - "T11988-", - "A11989-", - "C11990-", - "A11991-", - "C11992-", - "A11993-", - "T11994-", - "T11995-", - "A11996-", - "T11997-", - "T11998-", - "C11999-", - "C12000-", - "G12001-", - "T12002-", - "A12003-", - "C12004-", - "G12005-", - "G12006-", - "C12007-", - "T12008-", - "T12009-", - "T12010-", - "C12011-", - "C12012-", - "A12013-", - "T12014-", - "T12015-", - "C12016-", - "T12017-", - "C12018-", - "C12019-", - "A12020-", - "A12021-", - "A12022-", - "A12023-", - "A12024-", - "C12025-", - "A12026-", - "A12027-", - "T12028-", - "T12029-", - "T12030-", - "T12031-", - "A12032-", - "C12033-", - "C12034-", - "A12035-", - "A12036-", - "A12037-", - "T12038-", - "C12039-", - "T12040-", - "A12041-", - "A12042-", - "A12043-", - "T12044-", - "C12045-", - "T12046-", - "A12047-", - "C12048-", - "A12049-", - "T12050-", - "C12051-", - "T12052-", - "T12053-", - "T12054-", - "A12055-", - "T12056-", - "T12057-", - "G12058-", - "T12059-", - "A12060-", - "T12061-", - "C12062-", - "T12063-", - "A12064-", - "T12065-", - "A12066-", - "A12067-", - "T12068-", - "C12069-", - "A12070-", - "C12071-", - "T12072-", - "A12073-", - "T12074-", - "T12075-", - "T12076-", - "A12077-", - "G12078-", - "A12079-", - "T12080-", - "A12081-", - "A12082-", - "T12083-", - "C12084-", - "A12085-", - "G12086-", - "C12087-", - "C12088-", - "A12089-", - "T12090-", - "A12091-", - "A12092-", - "T12093-", - "T12094-", - "C12095-", - "C12096-", - "T12097-", - "C12098-", - "G12099-", - "A12100-", - "G12101-", - "T12102-", - "G12103-", - "C12104-", - "A12105-", - "A12106-", - "C12107-", - "A12108-", - "T12109-", - "G12110-", - "T12111-", - "T12112-", - "A12113-", - "G12114-", - "A12115-", - "T12116-", - "C12117-", - "G12118-", - "T12119-", - "C12120-", - "T12121-", - "A12122-", - "T12123-", - "A12124-", - "T12125-", - "A12126-", - "T12127-", - "G12128-", - "A12129-", - "A12130-", - "T12131-", - "A12132-", - "A12133-", - "G12134-", - "C12135-", - "C12136-", - "G12137-", - "T12138-", - "G12139-", - "T12140-", - "T12141-", - "A12142-", - "T12143-", - "C12144-", - "T12145-", - "A12146-", - "T12147-", - "T12148-", - "C12149-", - "C12150-", - "T12151-", - "T12152-", - "T12153-", - "C12154-", - "A12155-", - "T12156-", - "T12157-", - "A12158-", - "A12159-", - "C12160-", - "A12161-", - "A12162-", - "T12163-", - "T12164-", - "T12165-", - "A12166-", - "A12167-", - "C12168-", - "G12169-", - "A12170-", - "T12171-", - "G12172-", - "T12173-", - "C12174-", - "T12175-", - "A12176-", - "T12177-", - "A12178-", - "T12179-", - "C12180-", - "T12181-", - "A12182-", - "T12183-", - "A12184-", - "T12185-", - "G12186-", - "A12187-", - "G12188-", - "A12189-", - "T12190-", - "G12191-", - "A12192-", - "C12193-", - "T12194-", - "T12195-", - "A12196-", - "A12197-", - "T12198-", - "A12199-", - "T12200-", - "A12201-", - "A12202-", - "T12203-", - "A12204-", - "T12205-", - "T12206-", - "G12207-", - "A12208-", - "A12209-", - "G12210-", - "A12211-", - "G12212-", - "C12213-", - "T12214-", - "G12215-", - "T12216-", - "A12217-", - "C12218-", - "A12219-", - "A12220-", - "T12221-", - "A12222-", - "G12223-", - "T12224-", - "T12225-", - "T12226-", - "T12227-", - "T12228-", - "A12229-", - "T12230-", - "C12231-", - "T12232-", - "A12233-", - "T12234-", - "A12235-", - "G12236-", - "A12237-", - "A12238-", - "G82853A", - "A188349-", - "-196604A" - ], - "OPG023": [ - "S221X", - "S222-", - "I223-", - "D224-", - "K225-", - "N226-", - "Y227-", - "C228-", - "T229-", - "A230-", - "L231-", - "Q232-", - "Y233-", - "Y234-", - "I235-", - "K236-", - "S237-", - "S238-", - "H239-", - "I240-", - "D241-", - "I242-", - "D243-", - "I244-", - "V245-", - "K246-", - "L247-", - "L248-", - "M249-", - "K250-", - "G251-", - "I252-", - "D253-", - "N254-", - "T255-", - "A256-", - "Y257-", - "S258-", - "Y259-", - "I260-", - "D261-", - "D262-", - "L263-", - "T264-", - "C265-", - "C266-", - "T267-", - "R268-", - "G269-", - "I270-", - "M271-", - "A272-", - "D273-", - "Y274-", - "L275-", - "N276-", - "S277-", - "D278-", - "Y279-", - "R280-", - "Y281-", - "N282-", - "K283-", - "D284-", - "V285-", - "D286-", - "L287-", - "D288-", - "L289-", - "V290-", - "K291-", - "L292-", - "F293-", - "L294-", - "E295-", - "N296-", - "G297-", - "K298-", - "P299-", - "Y300-", - "G301-", - "I302-", - "M303-", - "C304-", - "S305-", - "I306-", - "V307-", - "P308-", - "L309-", - "W310-", - "R311-", - "N312-", - "D313-", - "K314-", - "E315-", - "T316-", - "I317-", - "S318-", - "L319-", - "I320-", - "L321-", - "K322-", - "T323-", - "M324-", - "N325-", - "S326-", - "D327-", - "V328-", - "L329-", - "Q330-", - "H331-", - "I332-", - "L333-", - "I334-", - "E335-", - "Y336-", - "M337-", - "T338-", - "F339-", - "G340-", - "D341-", - "I342-", - "D343-", - "I344-", - "P345-", - "L346-", - "V347-", - "E348-", - "C349-", - "M350-", - "L351-", - "E352-", - "Y353-", - "G354-", - "A355-", - "V356-", - "V357-", - "N358-", - "K359-", - "E360-", - "A361-", - "I362-", - "H363-", - "R364-", - "Y365-", - "F366-", - "R367-", - "N368-", - "I369-", - "N370-", - "I371-", - "D372-", - "S373-", - "Y374-", - "T375-", - "M376-", - "K377-", - "Y378-", - "L379-", - "L380-", - "K381-", - "K382-", - "E383-", - "G384-", - "G385-", - "D386-", - "A387-", - "V388-", - "N389-", - "H390-", - "L391-", - "D392-", - "D393-", - "G394-", - "E395-", - "I396-", - "P397-", - "I398-", - "G399-", - "H400-", - "L401-", - "C402-", - "E403-", - "S404-", - "N405-", - "Y406-", - "G407-", - "C408-", - "Y409-", - "N410-", - "F411-", - "Y412-", - "T413-", - "Y414-", - "T415-", - "Y416-", - "K417-", - "K418-", - "G419-", - "L420-", - "C421-", - "D422-", - "M423-", - "S424-", - "Y425-", - "V426-", - "C427-", - "P428-", - "I429-", - "L430-", - "S431-", - "T432-", - "I433-", - "N434-", - "I435-", - "C436-", - "L437-", - "P438-", - "Y439-", - "L440-", - "K441-", - "D442-", - "I443-", - "N444-", - "M445-", - "I446-", - "D447-", - "K448-", - "R449-", - "G450-", - "E451-", - "T452-", - "L453-", - "L454-", - "H455-", - "K456-", - "A457-", - "V458-", - "R459-", - "Y460-", - "N461-", - "K462-", - "Q463-", - "S464-", - "L465-", - "V466-", - "S467-", - "L468-", - "L469-", - "L470-", - "E471-", - "S472-", - "G473-", - "S474-", - "D475-", - "V476-", - "N477-", - "I478-", - "R479-", - "S480-", - "N481-", - "N482-", - "G483-", - "Y484-", - "T485-", - "C486-", - "I487-", - "T488-", - "I489-", - "A490-", - "I491-", - "N492-", - "E493-", - "S494-", - "R495-", - "N496-", - "I497-", - "E498-", - "L499-", - "L500-", - "K501-", - "M502-", - "L503-", - "L504-", - "C505-", - "H506-", - "K507-", - "P508-", - "T509-", - "L510-", - "D511-", - "C512-", - "V513-", - "I514-", - "D515-", - "S516-", - "L517-", - "S518-", - "E519-", - "V520-", - "S521-", - "N522-", - "I523-", - "V524-", - "D525-", - "*661X" - ] - }, - "labels": { - "aa": "OPG023: S221X, S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-, *661X" - } - } - }, - { - "name": "Monkeypox/PT0008/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Ferreira,R., Sobral,D., Nunes,A., Santos,J.D., Mixao,V., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Ferreira,R., Sobral,D., Nunes,A., Santos,J.D., Mixao,V., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal" - }, - "date": { - "value": "2022-05-15" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "strain_original": { - "value": "Monkeypox/PT0008/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON585038" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A11326-", - "T11327-", - "C11328-", - "T11329-", - "A11330-", - "C11331-", - "G11332-", - "A11333-", - "T11334-", - "A11335-", - "T11336-", - "T11337-", - "A11338-", - "G11339-", - "A11340-", - "T11341-", - "A11342-", - "C11343-", - "T11344-", - "T11345-", - "C11346-", - "A11347-", - "C11348-", - "T11349-", - "C11350-", - "A11351-", - "A11352-", - "T11353-", - "G11354-", - "A11355-", - "A11356-", - "T11357-", - "C11358-", - "A11359-", - "A11360-", - "T11361-", - "C11362-", - "A11363-", - "C11364-", - "A11365-", - "C11366-", - "A11367-", - "A11368-", - "T11369-", - "C11370-", - "T11371-", - "A11372-", - "A11373-", - "T11374-", - "G11375-", - "T11376-", - "A11377-", - "G11378-", - "G11379-", - "T11380-", - "T11381-", - "T11382-", - "A11383-", - "T11384-", - "G11385-", - "A11386-", - "C11387-", - "A11388-", - "T11389-", - "A11390-", - "A11391-", - "T11392-", - "A11393-", - "G11394-", - "C11395-", - "A11396-", - "T11397-", - "T11398-", - "T11399-", - "T11400-", - "C11401-", - "A11402-", - "G11403-", - "C11404-", - "A11405-", - "G11406-", - "T11407-", - "T11408-", - "C11409-", - "A11410-", - "A11411-", - "T11412-", - "G11413-", - "T11414-", - "T11415-", - "T11416-", - "C11417-", - "T11418-", - "A11419-", - "G11420-", - "A11421-", - "T11422-", - "T11423-", - "C11424-", - "G11425-", - "T11426-", - "T11427-", - "G11428-", - "A11429-", - "T11430-", - "G11431-", - "G11432-", - "C11433-", - "A11434-", - "A11435-", - "T11436-", - "G11437-", - "G11438-", - "T11439-", - "T11440-", - "A11441-", - "T11442-", - "A11443-", - "C11444-", - "A11445-", - "T11446-", - "G11447-", - "T11448-", - "A11449-", - "T11450-", - "A11451-", - "T11452-", - "C11453-", - "C11454-", - "G11455-", - "T11456-", - "T11457-", - "A11458-", - "T11459-", - "T11460-", - "T11461-", - "G11462-", - "A11463-", - "T11464-", - "C11465-", - "T11466-", - "A11467-", - "A11468-", - "T11469-", - "G11470-", - "T11471-", - "T11472-", - "G11473-", - "A11474-", - "C11475-", - "A11476-", - "T11477-", - "C11478-", - "T11479-", - "G11480-", - "A11481-", - "A11482-", - "C11483-", - "C11484-", - "G11485-", - "G11486-", - "A11487-", - "T11488-", - "T11489-", - "C11490-", - "T11491-", - "A11492-", - "G11493-", - "C11494-", - "A11495-", - "G11496-", - "T11497-", - "A11498-", - "A11499-", - "A11500-", - "G11501-", - "A11502-", - "T11503-", - "A11504-", - "C11505-", - "T11506-", - "A11507-", - "G11508-", - "A11509-", - "G11510-", - "A11511-", - "T11512-", - "T11513-", - "G11514-", - "T11515-", - "T11516-", - "T11517-", - "A11518-", - "T11519-", - "T11520-", - "A11521-", - "T11522-", - "A11523-", - "T11524-", - "C11525-", - "T11526-", - "A11527-", - "A11528-", - "C11529-", - "A11530-", - "G11531-", - "C11532-", - "C11533-", - "T11534-", - "T11535-", - "G11536-", - "T11537-", - "G11538-", - "A11539-", - "A11540-", - "G11541-", - "A11542-", - "A11543-", - "G11544-", - "T11545-", - "G11546-", - "T11547-", - "T11548-", - "T11549-", - "C11550-", - "T11551-", - "C11552-", - "C11553-", - "T11554-", - "C11555-", - "G11556-", - "T11557-", - "T11558-", - "T11559-", - "G11560-", - "T11561-", - "C11562-", - "A11563-", - "A11564-", - "T11565-", - "C11566-", - "A11567-", - "T11568-", - "G11569-", - "T11570-", - "T11571-", - "A11572-", - "A11573-", - "T11574-", - "G11575-", - "T11576-", - "C11577-", - "T11578-", - "T11579-", - "T11580-", - "A11581-", - "A11582-", - "G11583-", - "A11584-", - "T11585-", - "A11586-", - "A11587-", - "G11588-", - "G11589-", - "T11590-", - "A11591-", - "G11592-", - "A11593-", - "C11594-", - "A11595-", - "A11596-", - "A11597-", - "T11598-", - "G11599-", - "T11600-", - "T11601-", - "T11602-", - "A11603-", - "T11604-", - "A11605-", - "G11606-", - "T11607-", - "A11608-", - "C11609-", - "T11610-", - "A11611-", - "A11612-", - "G11613-", - "A11614-", - "A11615-", - "T11616-", - "T11617-", - "G11618-", - "G11619-", - "G11620-", - "C11621-", - "A11622-", - "A11623-", - "A11624-", - "C11625-", - "A11626-", - "T11627-", - "A11628-", - "A11629-", - "G11630-", - "A11631-", - "C11632-", - "A11633-", - "T11634-", - "G11635-", - "T11636-", - "C11637-", - "A11638-", - "C11639-", - "A11640-", - "A11641-", - "A11642-", - "G11643-", - "A11644-", - "C11645-", - "C11646-", - "C11647-", - "T11648-", - "T11649-", - "T11650-", - "T11651-", - "T11652-", - "G11653-", - "T11654-", - "A11655-", - "T11656-", - "G11657-", - "T11658-", - "A11659-", - "T11660-", - "A11661-", - "A11662-", - "G11663-", - "T11664-", - "G11665-", - "T11666-", - "A11667-", - "G11668-", - "A11669-", - "A11670-", - "A11671-", - "T11672-", - "T11673-", - "A11674-", - "T11675-", - "A11676-", - "A11677-", - "C11678-", - "A11679-", - "T11680-", - "C11681-", - "C11682-", - "A11683-", - "T11684-", - "A11685-", - "G11686-", - "T11687-", - "T11688-", - "G11689-", - "G11690-", - "A11691-", - "T11692-", - "T11693-", - "C11694-", - "A11695-", - "C11696-", - "A11697-", - "T11698-", - "A11699-", - "G11700-", - "G11701-", - "T11702-", - "G11703-", - "T11704-", - "C11705-", - "C11706-", - "A11707-", - "A11708-", - "T11709-", - "C11710-", - "G11711-", - "G11712-", - "G11713-", - "A11714-", - "T11715-", - "C11716-", - "T11717-", - "C11718-", - "T11719-", - "C11720-", - "C11721-", - "A11722-", - "T11723-", - "C11724-", - "A11725-", - "T11726-", - "C11727-", - "G11728-", - "A11729-", - "G11730-", - "A11731-", - "T11732-", - "G11733-", - "A11734-", - "T11735-", - "T11736-", - "G11737-", - "A11738-", - "C11739-", - "G11740-", - "G11741-", - "C11742-", - "A11743-", - "T11744-", - "C11745-", - "T11746-", - "C11747-", - "C11748-", - "C11749-", - "C11750-", - "C11751-", - "T11752-", - "T11753-", - "C11754-", - "C11755-", - "T11756-", - "T11757-", - "T11758-", - "T11759-", - "T11760-", - "T11761-", - "A11762-", - "G11763-", - "T11764-", - "A11765-", - "G11766-", - "A11767-", - "T11768-", - "A11769-", - "T11770-", - "T11771-", - "T11772-", - "C11773-", - "A11774-", - "T11775-", - "C11776-", - "G11777-", - "T11778-", - "G11779-", - "T11780-", - "A11781-", - "A11782-", - "G11783-", - "A11784-", - "A11785-", - "T11786-", - "C11787-", - "A11788-", - "A11789-", - "T11790-", - "A11791-", - "T11792-", - "T11793-", - "A11794-", - "A11795-", - "T11796-", - "A11797-", - "T11798-", - "T11799-", - "T11800-", - "C11801-", - "T11802-", - "A11803-", - "A11804-", - "A11805-", - "G11806-", - "T11807-", - "A11808-", - "T11809-", - "C11810-", - "T11811-", - "G11812-", - "T11813-", - "G11814-", - "T11815-", - "A11816-", - "T11817-", - "A11818-", - "G11819-", - "C11820-", - "C11821-", - "T11822-", - "C11823-", - "T11824-", - "T11825-", - "T11826-", - "A11827-", - "T11828-", - "T11829-", - "T11830-", - "A11831-", - "C11832-", - "C11833-", - "A11834-", - "C11835-", - "A11836-", - "G11837-", - "C11838-", - "T11839-", - "C11840-", - "C11841-", - "A11842-", - "T11843-", - "A11844-", - "T11845-", - "T11846-", - "C11847-", - "C11848-", - "A11849-", - "A11850-", - "C11851-", - "A11852-", - "T11853-", - "G11854-", - "C11855-", - "A11856-", - "T11857-", - "T11858-", - "C11859-", - "C11860-", - "A11861-", - "C11862-", - "T11863-", - "A11864-", - "G11865-", - "A11866-", - "G11867-", - "G11868-", - "G11869-", - "A11870-", - "T11871-", - "A11872-", - "T11873-", - "C11874-", - "G11875-", - "A11876-", - "T11877-", - "A11878-", - "T11879-", - "C11880-", - "G11881-", - "C11882-", - "C11883-", - "G11884-", - "A11885-", - "A11886-", - "T11887-", - "G11888-", - "T11889-", - "C11890-", - "A11891-", - "T11892-", - "A11893-", - "T11894-", - "A11895-", - "C11896-", - "T11897-", - "C11898-", - "A11899-", - "A11900-", - "T11901-", - "T11902-", - "A11903-", - "G11904-", - "T11905-", - "A11906-", - "T11907-", - "A11908-", - "T11909-", - "G11910-", - "T11911-", - "T11912-", - "G11913-", - "G11914-", - "A11915-", - "G11916-", - "G11917-", - "A11918-", - "C11919-", - "A11920-", - "T11921-", - "C11922-", - "C11923-", - "G11924-", - "A11925-", - "G11926-", - "T11927-", - "T11928-", - "C11929-", - "A11930-", - "T11931-", - "T11932-", - "G11933-", - "T11934-", - "T11935-", - "T11936-", - "T11937-", - "C11938-", - "A11939-", - "A11940-", - "T11941-", - "A11942-", - "T11943-", - "C11944-", - "A11945-", - "A11946-", - "A11947-", - "G11948-", - "A11949-", - "G11950-", - "A11951-", - "T11952-", - "G11953-", - "G11954-", - "T11955-", - "T11956-", - "T11957-", - "C11958-", - "C11959-", - "T11960-", - "T11961-", - "A11962-", - "T11963-", - "C11964-", - "A11965-", - "T11966-", - "T11967-", - "T11968-", - "C11969-", - "T11970-", - "C11971-", - "C11972-", - "A11973-", - "T11974-", - "A11975-", - "G11976-", - "T11977-", - "G11978-", - "G11979-", - "T11980-", - "A11981-", - "C11982-", - "A11983-", - "A11984-", - "T11985-", - "A11986-", - "C11987-", - "T11988-", - "A11989-", - "C11990-", - "A11991-", - "C11992-", - "A11993-", - "T11994-", - "T11995-", - "A11996-", - "T11997-", - "T11998-", - "C11999-", - "C12000-", - "G12001-", - "T12002-", - "A12003-", - "C12004-", - "G12005-", - "G12006-", - "C12007-", - "T12008-", - "T12009-", - "T12010-", - "C12011-", - "C12012-", - "A12013-", - "T12014-", - "T12015-", - "C12016-", - "T12017-", - "C12018-", - "C12019-", - "A12020-", - "A12021-", - "A12022-", - "A12023-", - "A12024-", - "C12025-", - "A12026-", - "A12027-", - "T12028-", - "T12029-", - "T12030-", - "T12031-", - "A12032-", - "C12033-", - "C12034-", - "A12035-", - "A12036-", - "A12037-", - "T12038-", - "C12039-", - "T12040-", - "A12041-", - "A12042-", - "A12043-", - "T12044-", - "C12045-", - "T12046-", - "A12047-", - "C12048-", - "A12049-", - "T12050-", - "C12051-", - "T12052-", - "T12053-", - "T12054-", - "A12055-", - "T12056-", - "T12057-", - "G12058-", - "T12059-", - "A12060-", - "T12061-", - "C12062-", - "T12063-", - "A12064-", - "T12065-", - "A12066-", - "A12067-", - "T12068-", - "C12069-", - "A12070-", - "C12071-", - "T12072-", - "A12073-", - "T12074-", - "T12075-", - "T12076-", - "A12077-", - "G12078-", - "A12079-", - "T12080-", - "A12081-", - "A12082-", - "T12083-", - "C12084-", - "A12085-", - "G12086-", - "C12087-", - "C12088-", - "A12089-", - "T12090-", - "A12091-", - "A12092-", - "T12093-", - "T12094-", - "C12095-", - "C12096-", - "T12097-", - "C12098-", - "G12099-", - "A12100-", - "G12101-", - "T12102-", - "G12103-", - "C12104-", - "A12105-", - "A12106-", - "C12107-", - "A12108-", - "T12109-", - "G12110-", - "T12111-", - "T12112-", - "A12113-", - "G12114-", - "A12115-", - "T12116-", - "C12117-", - "G12118-", - "T12119-", - "C12120-", - "T12121-", - "A12122-", - "T12123-", - "A12124-", - "T12125-", - "A12126-", - "T12127-", - "G12128-", - "A12129-", - "A12130-", - "T12131-", - "A12132-", - "A12133-", - "G12134-", - "C12135-", - "C12136-", - "G12137-", - "T12138-", - "G12139-", - "T12140-", - "T12141-", - "A12142-", - "T12143-", - "C12144-", - "T12145-", - "A12146-", - "T12147-", - "T12148-", - "C12149-", - "C12150-", - "T12151-", - "T12152-", - "T12153-", - "C12154-", - "A12155-", - "T12156-", - "T12157-", - "A12158-", - "A12159-", - "C12160-", - "A12161-", - "A12162-", - "T12163-", - "T12164-", - "T12165-", - "A12166-", - "A12167-", - "C12168-", - "G12169-", - "A12170-", - "T12171-", - "G12172-", - "T12173-", - "C12174-", - "T12175-", - "A12176-", - "T12177-", - "A12178-", - "T12179-", - "C12180-", - "T12181-", - "A12182-", - "T12183-", - "A12184-", - "T12185-", - "G12186-", - "A12187-", - "G12188-", - "A12189-", - "T12190-", - "G12191-", - "A12192-", - "C12193-", - "T12194-", - "T12195-", - "A12196-", - "A12197-", - "T12198-", - "A12199-", - "T12200-", - "A12201-", - "A12202-", - "T12203-", - "A12204-", - "T12205-", - "T12206-", - "G12207-", - "A12208-", - "A12209-", - "G12210-", - "A12211-", - "G12212-", - "C12213-", - "T12214-", - "G12215-", - "T12216-", - "A12217-", - "C12218-", - "A12219-", - "A12220-", - "T12221-", - "A12222-", - "G12223-", - "T12224-", - "T12225-", - "T12226-", - "T12227-", - "T12228-", - "A12229-", - "T12230-", - "C12231-", - "T12232-", - "A12233-", - "T12234-", - "A12235-", - "G12236-", - "A12237-", - "A12238-", - "C16968T", - "A188349-" - ], - "OPG023": [ - "S221X", - "S222-", - "I223-", - "D224-", - "K225-", - "N226-", - "Y227-", - "C228-", - "T229-", - "A230-", - "L231-", - "Q232-", - "Y233-", - "Y234-", - "I235-", - "K236-", - "S237-", - "S238-", - "H239-", - "I240-", - "D241-", - "I242-", - "D243-", - "I244-", - "V245-", - "K246-", - "L247-", - "L248-", - "M249-", - "K250-", - "G251-", - "I252-", - "D253-", - "N254-", - "T255-", - "A256-", - "Y257-", - "S258-", - "Y259-", - "I260-", - "D261-", - "D262-", - "L263-", - "T264-", - "C265-", - "C266-", - "T267-", - "R268-", - "G269-", - "I270-", - "M271-", - "A272-", - "D273-", - "Y274-", - "L275-", - "N276-", - "S277-", - "D278-", - "Y279-", - "R280-", - "Y281-", - "N282-", - "K283-", - "D284-", - "V285-", - "D286-", - "L287-", - "D288-", - "L289-", - "V290-", - "K291-", - "L292-", - "F293-", - "L294-", - "E295-", - "N296-", - "G297-", - "K298-", - "P299-", - "Y300-", - "G301-", - "I302-", - "M303-", - "C304-", - "S305-", - "I306-", - "V307-", - "P308-", - "L309-", - "W310-", - "R311-", - "N312-", - "D313-", - "K314-", - "E315-", - "T316-", - "I317-", - "S318-", - "L319-", - "I320-", - "L321-", - "K322-", - "T323-", - "M324-", - "N325-", - "S326-", - "D327-", - "V328-", - "L329-", - "Q330-", - "H331-", - "I332-", - "L333-", - "I334-", - "E335-", - "Y336-", - "M337-", - "T338-", - "F339-", - "G340-", - "D341-", - "I342-", - "D343-", - "I344-", - "P345-", - "L346-", - "V347-", - "E348-", - "C349-", - "M350-", - "L351-", - "E352-", - "Y353-", - "G354-", - "A355-", - "V356-", - "V357-", - "N358-", - "K359-", - "E360-", - "A361-", - "I362-", - "H363-", - "R364-", - "Y365-", - "F366-", - "R367-", - "N368-", - "I369-", - "N370-", - "I371-", - "D372-", - "S373-", - "Y374-", - "T375-", - "M376-", - "K377-", - "Y378-", - "L379-", - "L380-", - "K381-", - "K382-", - "E383-", - "G384-", - "G385-", - "D386-", - "A387-", - "V388-", - "N389-", - "H390-", - "L391-", - "D392-", - "D393-", - "G394-", - "E395-", - "I396-", - "P397-", - "I398-", - "G399-", - "H400-", - "L401-", - "C402-", - "E403-", - "S404-", - "N405-", - "Y406-", - "G407-", - "C408-", - "Y409-", - "N410-", - "F411-", - "Y412-", - "T413-", - "Y414-", - "T415-", - "Y416-", - "K417-", - "K418-", - "G419-", - "L420-", - "C421-", - "D422-", - "M423-", - "S424-", - "Y425-", - "V426-", - "C427-", - "P428-", - "I429-", - "L430-", - "S431-", - "T432-", - "I433-", - "N434-", - "I435-", - "C436-", - "L437-", - "P438-", - "Y439-", - "L440-", - "K441-", - "D442-", - "I443-", - "N444-", - "M445-", - "I446-", - "D447-", - "K448-", - "R449-", - "G450-", - "E451-", - "T452-", - "L453-", - "L454-", - "H455-", - "K456-", - "A457-", - "V458-", - "R459-", - "Y460-", - "N461-", - "K462-", - "Q463-", - "S464-", - "L465-", - "V466-", - "S467-", - "L468-", - "L469-", - "L470-", - "E471-", - "S472-", - "G473-", - "S474-", - "D475-", - "V476-", - "N477-", - "I478-", - "R479-", - "S480-", - "N481-", - "N482-", - "G483-", - "Y484-", - "T485-", - "C486-", - "I487-", - "T488-", - "I489-", - "A490-", - "I491-", - "N492-", - "E493-", - "S494-", - "R495-", - "N496-", - "I497-", - "E498-", - "L499-", - "L500-", - "K501-", - "M502-", - "L503-", - "L504-", - "C505-", - "H506-", - "K507-", - "P508-", - "T509-", - "L510-", - "D511-", - "C512-", - "V513-", - "I514-", - "D515-", - "S516-", - "L517-", - "S518-", - "E519-", - "V520-", - "S521-", - "N522-", - "I523-", - "V524-", - "D525-", - "*661X" - ] - }, - "labels": { - "aa": "OPG023: S221X, S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-, *661X" - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3336/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-06-01" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3336/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880538" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C32627T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-" - ] - } - } - }, - { - "name": "NODE_0000152", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C34432T" - ], - "OPG053": [ - "E87K" - ] - }, - "labels": { - "aa": "OPG053: E87K" - } - }, - "children": [ - { - "name": "NODE_0000153", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G37974A", - "C47521T", - "G90736A", - "T150558-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG056": [ - "S354L" - ], - "OPG111": [ - "D158N" - ] - }, - "labels": { - "aa": "OPG056: S354L; OPG111: D158N" - } - }, - "children": [ - { - "name": "NY-NYCPHL-000158", - "node_attrs": { - "div": 563, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-06-29" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "strain_original": { - "value": "NY-NYCPHL-000158" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ419004" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A74149T", - "T150544-", - "A150545-", - "T150546-", - "G150547-", - "A150548-", - "A150549-", - "G150550-", - "G150551-", - "A150552-", - "-150558A" - ], - "OPG094": [ - "T124S" - ] - }, - "labels": { - "aa": "OPG094: T124S" - } - } - }, - { - "name": "NODE_0000154", - "node_attrs": { - "div": 563, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G21065A", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567A" - ] - } - }, - "children": [ - { - "name": "NY-NYCPHL-000198", - "node_attrs": { - "div": 563, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-07-01" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "strain_original": { - "value": "NY-NYCPHL-000198" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469047" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150558T" - ] - } - } - }, - { - "name": "NY-NYCPHL-001101", - "node_attrs": { - "div": 563, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-07-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "strain_original": { - "value": "NY-NYCPHL-001101" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469275" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A150557-" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000155", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G155157A" - ], - "OPG181": [ - "R249K" - ] - }, - "labels": { - "aa": "OPG181: R249K" - } - }, - "children": [ - { - "name": "Monkeypox/PT0191/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-06-28" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "strain_original": { - "value": "Monkeypox/PT0191/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP324505" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G4195A", - "C193015T", - "-196603A", - "-196604A" - ], - "OPG003": [ - "S138L" - ] - }, - "labels": { - "aa": "OPG003: S138L" - } - } - }, - { - "name": "Monkeypox/PT0215/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-06-24" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "strain_original": { - "value": "Monkeypox/PT0215/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP324525" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0386/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-07-12" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "strain_original": { - "value": "Monkeypox/PT0386/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555482" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C24614T", - "C134192T" - ], - "OPG040": [ - "E289K" - ] - }, - "labels": { - "aa": "OPG040: E289K" - } - } - }, - { - "name": "Monkeypox/PT0477/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "strain_original": { - "value": "Monkeypox/PT0477/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555556" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0500/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-12" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.9" - }, - "strain_original": { - "value": "Monkeypox/PT0500/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555574" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000163", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C18133T", - "G67611A", - "G130231A", - "G159277A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-196603A" - ], - "OPG185": [ - "E121K" - ] - }, - "labels": { - "aa": "OPG185: E121K", - "clade": "B.1.11" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-070499/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-070499/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP169336" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV22/human/USA-NE-115", - "node_attrs": { - "div": 561, - "author": { - "author": "Tegomoh,B., Cross,S.T., Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., Pratt,C.B., Warden,D.E., Iwen,P.C., Donahue,M., Wiley,M.R.", - "value": "Tegomoh,B., Cross,S.T., Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., Pratt,C.B., Warden,D.E., Iwen,P.C., Donahue,M., Wiley,M.R." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health" - }, - "date": { - "value": "2022-08-04" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "MPXV22/human/USA-NE-115" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP314960" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "C94099T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "-196601A", - "-196602A" - ], - "OPG113": [ - "A790V" - ] - }, - "labels": { - "aa": "OPG113: A790V" - } - } - }, - { - "name": "MAG-UNIMOL-MPX-292982-L", - "node_attrs": { - "div": 560, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "date": { - "value": "2022-08-20" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "MAG-UNIMOL-MPX-292982-L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP390178" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-", - "A196603-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI404", - "node_attrs": { - "div": 561, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI404" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP524006" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "G182634A" - ], - "OPG210": [ - "D427N" - ] - }, - "labels": { - "aa": "OPG210: D427N" - } - } - }, - { - "name": "MPXV-USA-IL-IDPH-062", - "node_attrs": { - "div": 560, - "author": { - "author": "Gagnon,K.T.", - "value": "Gagnon,K.T." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry" - }, - "date": { - "value": "2022-06-22" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "MPXV-USA-IL-IDPH-062" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536723" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "-196601A", - "-196602A" - ] - } - } - }, - { - "name": "Monkeypox/PT0466/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "Monkeypox/PT0466/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555545" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "hMPX/USA/CA-LACPHL-MA00178/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-08-07" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "hMPX/USA/CA-LACPHL-MA00178/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP580611" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "CUN_INS_MPX_0751_C", - "node_attrs": { - "div": 562, - "author": { - "author": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M.", - "value": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "date": { - "value": "2022-09-10" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "CUN_INS_MPX_0751_C" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP693656" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C33832T", - "C42036T", - "A196603-" - ], - "OPG052": [ - "R55Q" - ] - }, - "labels": { - "aa": "OPG052: R55Q" - } - } - }, - { - "name": "SAN_INS_MPX_0973_L", - "node_attrs": { - "div": 563, - "author": { - "author": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M.", - "value": "Laiton-Donato,K.D., Franco,C.E., Alvarez-Diaz,D.A., Ruiz-Moreno,H.A., Prada,D.A., Martinez,D., Mercado-Reyes,M.M." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "date": { - "value": "2022-10-17" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "SAN_INS_MPX_0973_L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP819960" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T19741-", - "A19742-", - "G19743-", - "G19744-", - "C19745-", - "G19746-", - "G27840A", - "C64404T", - "C96810T", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-" - ], - "OPG034": [ - "T87X", - "P88-", - "K89X", - "*215X" - ], - "OPG043": [ - "S39F" - ], - "OPG083": [ - "D105N" - ] - }, - "labels": { - "aa": "OPG034: T87X, P88-, K89X, *215X; OPG043: S39F; OPG083: D105N" - } - } - }, - { - "name": "BOL-UNIMOL-MPX-293614-L", - "node_attrs": { - "div": 560, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "date": { - "value": "2022-11-11" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "BOL-UNIMOL-MPX-293614-L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP959062" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "LBMB-UTP_MP-001_QUI", - "node_attrs": { - "div": 563, - "author": { - "author": "Tabares,F.A., Anacona,J.D., Mora,P.A., Orjuela,M., Zuluaga,A., Sepulveda,J.C.", - "value": "Tabares,F.A., Anacona,J.D., Mora,P.A., Orjuela,M., Zuluaga,A., Sepulveda,J.C." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud" - }, - "date": { - "value": "2022-09-14" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "LBMB-UTP_MP-001_QUI" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ107058" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T509-", - "T510-", - "A511-", - "C58682T", - "C170573T", - "G178744A", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-" - ], - "OPG078": [ - "G44S" - ], - "OPG198": [ - "S179L" - ] - }, - "labels": { - "aa": "OPG078: G44S; OPG198: S179L" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-28220C", - "node_attrs": { - "div": 560, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-10-13" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-28220C" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ261700" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox virus/Human/USA/CA-LACPHL-MA00364/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-10-11" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "Monkeypox virus/Human/USA/CA-LACPHL-MA00364/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ330984" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A581-", - "G582-", - "A583-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "NY-NYCPHL-001029", - "node_attrs": { - "div": 561, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-07-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "NY-NYCPHL-001029" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468561" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "T150544-", - "A150545-", - "T150546-", - "G150547-", - "A150548-", - "A150549-", - "G150550-", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558A", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C172443T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "NY-NYCPHL-000172", - "node_attrs": { - "div": 562, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-06-28" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "NY-NYCPHL-000172" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ504411" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G23528A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150565G", - "-150566A", - "-150567T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "G179412A" - ], - "OPG208": [ - "M49I" - ] - }, - "labels": { - "aa": "OPG208: M49I" - } - } - }, - { - "name": "hMpxV/USA/CA-CDPH-1MPX1000208/2023", - "node_attrs": { - "div": 561, - "author": { - "author": "Haw,M., Kath,C., Espinosa,A., O'Neil,R., Hacker,J.", - "value": "Haw,M., Kath,C., Espinosa,A., O'Neil,R., Hacker,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "date": { - "value": "2022-07-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "hMpxV/USA/CA-CDPH-1MPX1000208/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ603477" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G23110A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG038": [ - "S17L" - ] - }, - "labels": { - "aa": "OPG038: S17L" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-30087C", - "node_attrs": { - "div": 563, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-11-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-30087C" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ696094" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T220-", - "T221-", - "A222-", - "C42840T", - "C55000T", - "G67730A", - "A196376-", - "T196377-", - "C196378-" - ], - "NBT03_gp052": [ - "E48K" - ], - "OPG085": [ - "R268C" - ] - }, - "labels": { - "aa": "NBT03_gp052: E48K; OPG085: R268C" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-3668E", - "node_attrs": { - "div": 563, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2023-02-16" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-3668E" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ957072" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C35308T", - "G71777A", - "C120979T" - ], - "OPG054": [ - "R230H" - ], - "OPG138": [ - "D52N" - ] - }, - "labels": { - "aa": "OPG054: R230H; OPG138: D52N" - } - } - }, - { - "name": "MPXV/UZ_REGA_113", - "node_attrs": { - "div": 563, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-10-28" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_113" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035719" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133099-", - "C142797T", - "C167995T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "G189258A", - "A196603-" - ], - "OPG164": [ - "S7L" - ], - "OPG193": [ - "S221F" - ] - }, - "labels": { - "aa": "OPG164: S7L; OPG193: S221F" - } - } - }, - { - "name": "MPXV/UZ_REGA_235/Belgium/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-08-12" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_235/Belgium/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR095053" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "A196603-" - ] - } - } - }, - { - "name": "MPXV_USA_2022_TX0052", - "node_attrs": { - "div": 563, - "author": { - "author": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y.", - "value": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-12-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "MPXV_USA_2022_TX0052" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR209310" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G19458A", - "G74374A", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "C185455T", - "A196603-" - ], - "OPG034": [ - "S183L" - ], - "OPG094": [ - "E199K" - ], - "OPG210": [ - "S1367L" - ] - }, - "labels": { - "aa": "OPG034: S183L; OPG094: E199K; OPG210: S1367L" - } - } - }, - { - "name": "NODE_0000164", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G37469A", - "C89777T" - ], - "OPG110": [ - "P49L" - ] - }, - "labels": { - "aa": "OPG110: P49L" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-091162/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-091162/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP743980" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/USA/WA-UW-098348/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-098348/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP743986" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000165", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G39327A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G177273A", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG057": [ - "A290V" - ], - "OPG205": [ - "D540N" - ] - }, - "labels": { - "aa": "OPG057: A290V; OPG205: D540N" - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00324/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-10-26" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00324/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP890529" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A573-", - "A577-", - "A579G", - "A179227-", - "T179228-", - "T179229-", - "A179230-", - "T179231-", - "A179232-", - "T179233-", - "A179234-", - "C179235-", - "A179236-", - "T179237-", - "T179238-", - "A179239-", - "T179240-", - "A179241-", - "T179242-", - "A179243-", - "T179244-", - "T196579-", - "G196580-", - "G196581-" - ] - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00344/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-11-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.11" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00344/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP920682" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000166", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G34308A", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG053": [ - "S128L" - ] - }, - "labels": { - "aa": "OPG053: S128L", - "clade": "B.1.4" - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-2833/2022", - "node_attrs": { - "div": 558, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-05-13" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-2833/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880519" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T85846C" - ], - "OPG107": [ - "M112T" - ] - }, - "labels": { - "aa": "OPG107: M112T" - } - } - }, - { - "name": "MPXV_USA_2022_CO0003", - "node_attrs": { - "div": 560, - "author": { - "author": "Gigante,C.M., Steidley,B., Seabolt,M.H., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Davizon,E.S., Li,Y.", - "value": "Gigante,C.M., Steidley,B., Seabolt,M.H., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Davizon,E.S., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MPXV_USA_2022_CO0003" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP185714" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C18027T", - "T159165C", - "G162156A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C" - ], - "OPG031": [ - "D268N" - ] - }, - "labels": { - "aa": "OPG031: D268N" - } - } - }, - { - "name": "ATL-UNIMOL-MPX-292896-L", - "node_attrs": { - "div": 558, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "date": { - "value": "2022-08-13" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "ATL-UNIMOL-MPX-292896-L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP390177" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C176447T", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "NODE_0000167", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C10672T", - "G112481A", - "G163626A" - ], - "OPG022": [ - "E63K" - ] - }, - "labels": { - "aa": "OPG022: E63K" - } - }, - "children": [ - { - "name": "NODE_0000168", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A87705G", - "A132985-", - "T132987-", - "T132989-", - "T132990-", - "T132991-" - ] - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-4119/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Griffiths,E., Jolly,G., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Griffiths,E., Jolly,G., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-07-04" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-4119/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP279049" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C132984-", - "G132986-", - "C132988-", - "-179226C" - ] - } - } - }, - { - "name": "HRYC_MPXV002", - "node_attrs": { - "div": 564, - "author": { - "author": "Ponce-Alonso,M., Martinez-Garcia,L., Olavarrieta,L., Galan,J.C.", - "value": "Ponce-Alonso,M., Martinez-Garcia,L., Olavarrieta,L., Galan,J.C." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Hospital Ramon y Cajal, Microbiology" - }, - "date": { - "value": "2023-03-23" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "HRYC_MPXV002" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR126132" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6376A", - "G11924A", - "G21674A", - "-132985A", - "-132987T", - "-132989T", - "-132990T", - "-132991T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "C190834T" - ], - "NBT03_gp174": [ - "S142L" - ], - "OPG023": [ - "S326L" - ], - "OPG037": [ - "L254F" - ] - }, - "labels": { - "aa": "NBT03_gp174: S142L; OPG023: S326L; OPG037: L254F" - } - } - } - ] - }, - { - "name": "NODE_0000169", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G144478A" - ] - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-3214/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-05-30" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3214/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880511" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000170", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "G185991A" - ], - "OPG210": [ - "D1546N" - ] - }, - "labels": { - "aa": "OPG210: D1546N" - } - }, - "children": [ - { - "name": "MPXV22/human/USA-OK-134", - "node_attrs": { - "div": 563, - "author": { - "author": "Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., O'Dell,J.X., Mannell,M., Wiley,M.R., Cross,S.T.", - "value": "Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., O'Dell,J.X., Mannell,M., Wiley,M.R., Cross,S.T." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health" - }, - "date": { - "value": "2022-08-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MPXV22/human/USA-OK-134" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP351286" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G84534A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "-196601A", - "-196602A", - "-196603A" - ], - "OPG105": [ - "D1137N" - ] - }, - "labels": { - "aa": "OPG105: D1137N" - } - } - }, - { - "name": "MPXV_USA_2022_FL0025", - "node_attrs": { - "div": 564, - "author": { - "author": "Gigante,C.M., Lee,P., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Morrison,S.S., Desch,M., Knipe,K., Weigand,M.R., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Stanek,D., Li,Y.", - "value": "Gigante,C.M., Lee,P., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Morrison,S.S., Desch,M., Knipe,K., Weigand,M.R., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Stanek,D., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MPXV_USA_2022_FL0025" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP752106" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C57339T", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "A173300-", - "T173301-", - "A173302-", - "T173303-", - "A173304-", - "T173305-", - "A173306-", - "T173307-", - "A173308-", - "T173309-", - "A173310-", - "T173311-", - "A173312-", - "T173313-", - "A173314-", - "T173315-", - "A173316-", - "T173317-", - "G176716A" - ], - "OPG075": [ - "E54K" - ], - "OPG205": [ - "G354D" - ] - }, - "labels": { - "aa": "OPG075: E54K; OPG205: G354D" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000171", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C24995T", - "G85774A", - "G148427A", - "G189258A" - ], - "OPG040": [ - "D162N" - ], - "OPG107": [ - "R88K" - ] - }, - "labels": { - "aa": "OPG040: D162N; OPG107: R88K" - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-2930/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Knox,N., Hole,D., Duggan,A., Yadav,C., Haidl,E., Chapel,M., Graham,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Hagan,M., Griffiths,E., Leung,A., Safronetz,D., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Knox,N., Hole,D., Duggan,A., Yadav,C., Haidl,E., Chapel,M., Graham,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Hagan,M., Griffiths,E., Leung,A., Safronetz,D., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-05-21" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-2930/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON803414" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-2906/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Jolly,G., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Griffiths,E., Leung,A., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-05-20" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-2906/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880505" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3532/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Marchand-Austin,A., Eshaghi,A., Patel,S.N., Hasso,M., Gubbay,J.B., Olsha,R.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Marchand-Austin,A., Eshaghi,A., Patel,S.N., Hasso,M., Gubbay,J.B., Olsha,R." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-06-07" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3532/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON983163" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3558/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Marchand-Austin,A., Eshaghi,A., Patel,S.N., Hasso,M., Gubbay,J.B., Olsha,R.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Marchand-Austin,A., Eshaghi,A., Patel,S.N., Hasso,M., Gubbay,J.B., Olsha,R." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-06-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3558/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON983164" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G167106A" - ], - "OPG192": [ - "E126K" - ] - }, - "labels": { - "aa": "OPG192: E126K" - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-4094/2022", - "node_attrs": { - "div": 565, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Griffiths,E., Jolly,G., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Griffiths,E., Jolly,G., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-07-06" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-4094/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP279033" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G8373A", - "C19191T", - "G103142A", - "C105161T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "-196603A" - ], - "OPG122": [ - "E239K" - ], - "OPG124": [ - "D270N" - ] - }, - "labels": { - "aa": "OPG122: E239K; OPG124: D270N" - } - } - }, - { - "name": "MPXV_USA_2022_IL0006", - "node_attrs": { - "div": 562, - "author": { - "author": "Gigante,C., Ghinai,I., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Kerins,J., Li,Y.", - "value": "Gigante,C., Ghinai,I., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Kerins,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MPXV_USA_2022_IL0006" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ427147" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G131810A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C" - ], - "OPG151": [ - "D963N" - ] - }, - "labels": { - "aa": "OPG151: D963N" - } - } - }, - { - "name": "NODE_0000172", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G45236A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C" - ] - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-3936/2022", - "node_attrs": { - "div": 563, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Jolly,G., Griffiths,E., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Jolly,G., Griffiths,E., Charest,H., Levade,I., Fafard,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-06-30" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3936/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP062236" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G132531A", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "NODE_0000173", - "node_attrs": { - "div": 563, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G174962A" - ], - "OPG204": [ - "R144K" - ] - }, - "labels": { - "aa": "OPG204: R144K" - } - }, - "children": [ - { - "name": "MPX_J6xzTO_9000286", - "node_attrs": { - "div": 563, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MPX_J6xzTO_9000286" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415246" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPX_J6xzTO_9000287", - "node_attrs": { - "div": 564, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MPX_J6xzTO_9000287" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415247" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C81418T" - ], - "OPG105": [ - "S98L" - ] - }, - "labels": { - "aa": "OPG105: S98L" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000174", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G36259A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "G174543A", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI496", - "node_attrs": { - "div": 562, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI496" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP626135" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C40251T", - "-150567T", - "C154472T", - "G167517A", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179154C" - ], - "OPG058": [ - "D62N" - ], - "OPG181": [ - "H21Y" - ], - "OPG193": [ - "E62K" - ] - }, - "labels": { - "aa": "OPG058: D62N; OPG181: H21Y; OPG193: E62K" - } - } - }, - { - "name": "MPX/Human/USA/CA-LACPHL-MA00247/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-07-16" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MPX/Human/USA/CA-LACPHL-MA00247/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP722506" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000175", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C177720T", - "-196603A" - ], - "OPG205": [ - "R689C" - ] - }, - "labels": { - "aa": "OPG205: R689C" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-108160/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2022-10-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-108160/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503748" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A80755C", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "G159203A", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179154C", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C" - ], - "OPG104": [ - "C89G" - ], - "OPG185": [ - "G96E" - ] - }, - "labels": { - "aa": "OPG104: C89G; OPG185: G96E" - } - } - }, - { - "name": "hMpxV/USA/CACDPH1MPX1000185/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "date": { - "value": "2022-12-21" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "hMpxV/USA/CACDPH1MPX1000185/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ547900" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G92733A", - "-150567T" - ], - "OPG113": [ - "E335K" - ] - }, - "labels": { - "aa": "OPG113: E335K" - } - } - } - ] - }, - { - "name": "NODE_0000176", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C25967T", - "-196603A" - ], - "OPG042": [ - "W377*" - ] - }, - "labels": { - "aa": "OPG042: W377*" - } - }, - "children": [ - { - "name": "hMPX/Human/USA/CA-LACPHL-MA00086/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-08-01" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "hMPX/Human/USA/CA-LACPHL-MA00086/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP442553" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C188775T" - ] - } - } - }, - { - "name": "NODE_0000177", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C172792T" - ] - } - }, - "children": [ - { - "name": "NODE_0000178", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A136513-", - "T136514-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "A150557-", - "T150558-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "A150566-", - "A163469T", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-" - ], - "OPG153": [ - "D385X", - "*510X" - ], - "OPG189": [ - "E46V" - ] - }, - "labels": { - "aa": "OPG153: D385X, *510X; OPG189: E46V" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_CA0010", - "node_attrs": { - "div": 562, - "author": { - "author": "Gigante,C., Ventura,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nash,J., Li,Y.", - "value": "Gigante,C., Ventura,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nash,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MPXV_USA_2022_CA0010" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP881942" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C136515-", - "G150551-", - "G150556-", - "G150559-", - "G150560-", - "G150565-", - "-179128A", - "-179129T", - "-179130T", - "-179131A", - "-179132T", - "-179133A", - "-179134T", - "-179135A", - "-179136C", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179145C", - "-179146A", - "-179147T", - "-179148T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A", - "-179154C", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C" - ], - "OPG153": [ - "X385-", - "X510*" - ] - }, - "labels": { - "aa": "OPG153: X385-, X510*" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00452/2022", - "node_attrs": { - "div": 570, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-10-12" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00452/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503786" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G70435A", - "C125412T", - "-136513A", - "-136514T", - "C141442T", - "C141511T", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150566A", - "-150567T", - "G158709A", - "T172792C", - "-173274A", - "-173275T", - "-173276A", - "-173277T", - "-173278A", - "-173279T", - "-173280A", - "-173281T", - "-173282A", - "-173283T", - "-173284A", - "-173285T", - "-173286A", - "-173287T", - "-173288A", - "-173289T", - "G175698A", - "G176439A" - ], - "OPG145": [ - "S489L" - ], - "OPG153": [ - "X385D", - "X510*" - ], - "OPG161": [ - "S114L", - "S137F" - ], - "OPG205": [ - "D15N", - "D262N" - ] - }, - "labels": { - "aa": "OPG145: S489L; OPG153: X385D, X510*; OPG161: S114L, S137F; OPG205: D15N, D262N" - } - } - } - ] - }, - { - "name": "NODE_0000179", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T495-", - "A496-", - "T497-", - "C97805T", - "-150567T" - ], - "OPG117": [ - "P586L" - ] - }, - "labels": { - "aa": "OPG117: P586L" - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00304/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-09-29" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00304/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP890538" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00343/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-11-10" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00343/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP920681" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00469/2022", - "node_attrs": { - "div": 564, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-11-18" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.4" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00469/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ644775" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C100640T", - "C105632T" - ], - "OPG124": [ - "E113K" - ] - }, - "labels": { - "aa": "OPG124: E113K" - } - } - } - ] - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000180", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G1302A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150565G", - "-150566A", - "-150567T", - "C182950T" - ], - "OPG210": [ - "S532L" - ] - }, - "labels": { - "aa": "OPG210: S532L", - "clade": "B.1.12" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/ON/RKI866", - "node_attrs": { - "div": 557, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI866" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773485" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A" - ] - } - } - }, - { - "name": "NODE_0000181", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G78328A", - "C195908T" - ], - "OPG001": [ - "L92F" - ] - }, - "labels": { - "aa": "OPG001: L92F" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI399", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI399" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP524001" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "NODE_0000182", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C57550T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150565-", - "A150566-", - "T150567-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ] - } - }, - "children": [ - { - "name": "MPX_BhVKjm_9000232", - "node_attrs": { - "div": 559, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "MPX_BhVKjm_9000232" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415206" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPX_BhVKjm_9000233", - "node_attrs": { - "div": 559, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "MPX_BhVKjm_9000233" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415207" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000183", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A1302G", - "G111084A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150565-", - "A150566-", - "T150567-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-3342/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-06-01" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3342/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880540" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G121510A" - ] - } - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3448/2022", - "node_attrs": { - "div": 558, - "author": { - "author": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Knox,N., Yadav,C., Haidl,E., Chapel,M., Domselaar,G.V., Fernando,L., Graham,M., Antonation,K., Audet,J., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-06-03" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3448/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880548" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/CAN/UN-NML-3276/2022", - "node_attrs": { - "div": 558, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Chapel,M., Tyler,A., Haidl,E., Domselaar,G.V., Antonation,K., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Jolly,G., Fafard,J., Charest,H., Levade,I.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Chapel,M., Tyler,A., Haidl,E., Domselaar,G.V., Antonation,K., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Graham,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Jolly,G., Fafard,J., Charest,H., Levade,I." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-05-31" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3276/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP013003" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000184", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G98233A", - "G98455A", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG117": [ - "D729N" - ], - "OPG118": [ - "G4R" - ] - }, - "labels": { - "aa": "OPG117: D729N; OPG118: G4R" - } - }, - "children": [ - { - "name": "MPX/BR0002/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Coletti,T.M., Ghilardi,F., khan,M.J., Claro,I.M., Valenca,I.N., Faria,N.R., Sabino,E.C.", - "value": "Coletti,T.M., Ghilardi,F., khan,M.J., Claro,I.M., Valenca,I.N., Faria,N.R., Sabino,E.C." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Imperial College London, School of Public Health" - }, - "date": { - "value": "2022-06-14" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "MPX/BR0002/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON880413" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Brazil" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C76334T", - "T133094-", - "T133095-", - "T133096-", - "T133097-", - "T133098-", - "T133099-", - "G173165-", - "C173166-", - "G173167-", - "G173168-" - ], - "OPG097": [ - "R181K" - ] - }, - "labels": { - "aa": "OPG097: R181K" - } - } - }, - { - "name": "NODE_0000185", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G98456A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T" - ], - "OPG118": [ - "R4K" - ] - }, - "labels": { - "aa": "OPG118: R4K" - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-3972/2022", - "node_attrs": { - "div": 564, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Griffiths,E., Jolly,G., Charest,H., Levade,I., Fafard,J.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Hagan,M., Safronetz,D., Leung,A., Peters,G., Go,A., Laminman,V., Kaplen,B., Antonation,K., Griffiths,E., Jolly,G., Charest,H., Levade,I., Fafard,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-07-04" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-3972/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP270022" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G3361A", - "C152970T", - "G181349A", - "C193849T" - ], - "OPG003": [ - "S416L" - ] - }, - "labels": { - "aa": "OPG003: S416L" - } - } - }, - { - "name": "MPXV_USA_2022_FL0017", - "node_attrs": { - "div": 561, - "author": { - "author": "Gigante,C.M., Lee,P., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Mendoza,R., Li,Y.", - "value": "Gigante,C.M., Lee,P., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Mendoza,R., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "MPXV_USA_2022_FL0017" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP303780" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-" - ] - } - } - }, - { - "name": "NY-NYCPHL-000897", - "node_attrs": { - "div": 562, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-06-30" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "NY-NYCPHL-000897" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ419075" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133099-", - "T150544-", - "A150545-", - "T150546-", - "G150547-", - "A150548-", - "A150549-", - "G150550-", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558A", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G158237A" - ] - } - } - }, - { - "name": "NY-NYCPHL-000410", - "node_attrs": { - "div": 564, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-08-26" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "NY-NYCPHL-000410" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ504432" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T67849G", - "G72382A", - "C157459T" - ], - "OPG085": [ - "N228T" - ], - "OPG092": [ - "S189F" - ] - }, - "labels": { - "aa": "OPG085: N228T; OPG092: S189F" - } - } - }, - { - "name": "MPXV_USA_2022_TN0019", - "node_attrs": { - "div": 564, - "author": { - "author": "Gigante,C., Thomas,L., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Dunn,J., Li,Y.", - "value": "Gigante,C., Thomas,L., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Dunn,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-12-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "MPXV_USA_2022_TN0019" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR209309" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C93601T", - "C94418T", - "T133098-", - "T133099-", - "C136029T" - ], - "OPG113": [ - "A624V" - ], - "OPG114": [ - "E84K" - ] - }, - "labels": { - "aa": "OPG113: A624V; OPG114: E84K" - } - } - }, - { - "name": "NODE_0000186", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C24231T" - ] - } - }, - "children": [ - { - "name": "NY-NYCPHL-000517", - "node_attrs": { - "div": 565, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-07-25" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "NY-NYCPHL-000517" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ504455" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G3110A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C163968T", - "C166400T", - "C194100T" - ], - "OPG003": [ - "R500W" - ] - }, - "labels": { - "aa": "OPG003: R500W" - } - } - }, - { - "name": "NY-NYCPHL-000899", - "node_attrs": { - "div": 563, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-07-07" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "NY-NYCPHL-000899" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ565499" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A81782T", - "-150551G", - "-150552A", - "-150561A", - "-150562T", - "-150563A" - ], - "OPG105": [ - "E219D" - ] - }, - "labels": { - "aa": "OPG105: E219D" - } - } - }, - { - "name": "NODE_0000187", - "node_attrs": { - "div": 563, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G61102A" - ], - "OPG080": [ - "S306F" - ] - }, - "labels": { - "aa": "OPG080: S306F" - } - }, - "children": [ - { - "name": "MPXV/UZ_REGA_214/Belgium/2022", - "node_attrs": { - "div": 563, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-08-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_214/Belgium/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR095032" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/UZ_REGA_215/Belgium/2022", - "node_attrs": { - "div": 563, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-08-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_215/Belgium/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR095033" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000188", - "node_attrs": { - "div": 563, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-", - "G184227A" - ], - "OPG210": [ - "D958N" - ] - }, - "labels": { - "aa": "OPG210: D958N" - } - }, - "children": [ - { - "name": "hMPXV-IHU00008", - "node_attrs": { - "div": 563, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "date": { - "value": "2022-07-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "hMPXV-IHU00008" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP382485" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T591-", - "A592-", - "-594T" - ] - } - } - }, - { - "name": "BOL-UNIMOL-MPX-293015-L", - "node_attrs": { - "div": 563, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "date": { - "value": "2022-08-24" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "BOL-UNIMOL-MPX-293015-L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP390179" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "MPX_ilzdZn_9000269", - "node_attrs": { - "div": 564, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "MPX_ilzdZn_9000269" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415236" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G23457A", - "A178020-", - "T178021-", - "A178022-", - "A178023-", - "T178024-", - "G178025-", - "A178026-", - "A178027-", - "T178028-", - "A178029-", - "C178030-", - "A178031-", - "C178032-", - "A178033-", - "T178034-", - "A178035-", - "C178036-", - "A178037-" - ], - "OPG039": [ - "S221F" - ] - }, - "labels": { - "aa": "OPG039: S221F" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000189", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G153910A" - ], - "OPG180": [ - "E407K" - ] - }, - "labels": { - "aa": "OPG180: E407K" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_NY0039", - "node_attrs": { - "div": 563, - "author": { - "author": "Gigante,C., Ruiz,V., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Wang,J., Li,Y.", - "value": "Gigante,C., Ruiz,V., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Wang,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-10-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "MPXV_USA_2022_NY0039" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ427114" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G71407A", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-" - ], - "OPG091": [ - "R13K" - ] - }, - "labels": { - "aa": "OPG091: R13K" - } - } - }, - { - "name": "MPXV_USA_2022_UT0006", - "node_attrs": { - "div": 564, - "author": { - "author": "Gigante,C., Murray,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Knipe,K., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Atkinson,A., Li,Y.", - "value": "Gigante,C., Murray,J., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Knipe,K., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Atkinson,A., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "MPXV_USA_2022_UT0006" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ427128" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G11924A", - "G152588A", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-", - "A196604-" - ], - "OPG023": [ - "S326L" - ] - }, - "labels": { - "aa": "OPG023: S326L" - } - } - }, - { - "name": "NY-NYCPHL-000257", - "node_attrs": { - "div": 562, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-08-02" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "NY-NYCPHL-000257" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469182" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000190", - "node_attrs": { - "div": 563, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G28483A" - ] - } - }, - "children": [ - { - "name": "MPXV/Human/USA/UT-UPHL-82200386/2022", - "node_attrs": { - "div": 568, - "author": { - "author": "Iverson,T., Oakeson,K.F., Young,E.L., Wagner,J., Hergert,J.", - "value": "Iverson,T., Oakeson,K.F., Young,E.L., Wagner,J., Hergert,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Utah Public Health Laboratory, Utah Public Health Laboratory Infectious Disease submission group" - }, - "date": { - "value": "2022-09-15" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "MPXV/Human/USA/UT-UPHL-82200386/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR026630" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C15582T", - "A37326C", - "T55658A", - "C122936T", - "G170349A" - ], - "OPG056": [ - "I570R" - ], - "OPG074": [ - "T490S" - ], - "OPG143": [ - "R127Q" - ] - }, - "labels": { - "aa": "OPG056: I570R; OPG074: T490S; OPG143: R127Q" - } - } - }, - { - "name": "NODE_0000191", - "node_attrs": { - "div": 564, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C21910T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG037": [ - "R175K" - ] - }, - "labels": { - "aa": "OPG037: R175K" - } - }, - "children": [ - { - "name": "NY-NYCPHL-001187", - "node_attrs": { - "div": 564, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2023-01-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "NY-NYCPHL-001187" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ419087" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150577-", - "A150578-", - "T150579-", - "A150580-", - "T150581-", - "G150582-", - "A150583-", - "T150584-" - ] - } - } - }, - { - "name": "NY-NYCPHL-001188", - "node_attrs": { - "div": 566, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2023-01-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "NY-NYCPHL-001188" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ419088" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C47537T", - "C104712T", - "T150587-", - "A150588-", - "T150589-", - "G150590-" - ], - "OPG123": [ - "R120K" - ] - }, - "labels": { - "aa": "OPG123: R120K" - } - } - }, - { - "name": "NY-NYCPHL-000631", - "node_attrs": { - "div": 567, - "author": { - "author": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-10-04" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "NY-NYCPHL-000631" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468616" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A76036T", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "C165073T", - "C168386T" - ], - "OPG195": [ - "H53Y" - ] - }, - "labels": { - "aa": "OPG195: H53Y" - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00490/2023", - "node_attrs": { - "div": 567, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2023-02-10" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.12" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00490/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ918701" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G39552A", - "T57420-", - "A57421-", - "C57422-", - "A57423-", - "A57424-", - "A57425-", - "A57426-", - "A57427-", - "G57428-", - "G57429-", - "A57430-", - "C57431-", - "A57432-", - "T57433-", - "G57434-", - "T57435-", - "A57436-", - "A57437-", - "A57438-", - "C57439-", - "T57440-", - "G132490A", - "C150443T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-" - ], - "OPG057": [ - "S215F" - ], - "OPG075": [ - "K20X", - "F21-", - "T22-", - "C23-", - "P24-", - "F25-", - "C26-", - "R27X", - "*109X" - ], - "OPG176": [ - "T212I" - ] - }, - "labels": { - "aa": "OPG057: S215F; OPG075: K20X, F21-, T22-, C23-, P24-, F25-, C26-, R27X, *109X; OPG176: T212I" - } - } - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000192", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G36617A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150559G", - "C159779T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG055": [ - "S156L" - ], - "OPG185": [ - "S288L" - ] - }, - "labels": { - "aa": "OPG055: S156L; OPG185: S288L", - "clade": "B.1.14" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI019", - "node_attrs": { - "div": 560, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI019" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON694330" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C3837T", - "G16608A", - "-150551G", - "-150552A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A169745T", - "A169749T", - "A192424-", - "T192425-", - "A192426-", - "A192427-", - "G192428-", - "T192429-", - "T192430-", - "A192431-", - "G192432-", - "T192433-", - "T192434-", - "A192435-", - "A192436-", - "G192437-", - "T192438-", - "C192439-", - "A192440-", - "T192441-", - "A192442-", - "A192443-", - "G192444-", - "T192445-", - "T192446-", - "A192447-", - "G192448-", - "T192449-", - "T192450-", - "A192451-", - "A192452-", - "G192453-", - "T192454-", - "C192455-", - "A192456-", - "T192457-", - "A192458-", - "A192459-", - "G192460-", - "T192461-", - "T192462-", - "A192463-", - "G192464-", - "T192465-", - "T192466-", - "A192467-", - "A192468-", - "G192469-", - "T192470-", - "C192471-", - "G193373A", - "A196604-" - ], - "OPG197": [ - "T26S", - "D27V" - ] - }, - "labels": { - "aa": "OPG197: T26S, D27V" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI011", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI011" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON694342" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A192440-", - "T192441-", - "A192442-", - "A192443-", - "G192444-", - "T192445-", - "T192446-", - "A192447-", - "G192448-", - "T192449-", - "T192450-", - "A192451-", - "A192452-", - "G192453-", - "T192454-", - "C192455-", - "A192456-", - "T192457-", - "A192458-", - "A192459-", - "G192460-", - "T192461-", - "T192462-", - "A192463-", - "G192464-", - "T192465-", - "T192466-", - "A192467-", - "A192468-", - "G192469-", - "T192470-", - "C192471-" - ] - } - } - }, - { - "name": "MPXV_USA_2022_NY004", - "node_attrs": { - "div": 560, - "author": { - "author": "Gigante,C.M., Hughes,S., Seabolt,M.H., Zhao,H., Wilkins,K., Respress,J., Howard,D., Batra,D., McCollum,A., Hutson,C., Davidson,W., Rao,A., Baumgartner,J., Li,Y.", - "value": "Gigante,C.M., Hughes,S., Seabolt,M.H., Zhao,H., Wilkins,K., Respress,J., Howard,D., Batra,D., McCollum,A., Hutson,C., Davidson,W., Rao,A., Baumgartner,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPXV_USA_2022_NY004" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON959135" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G2132A", - "G96835A", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "G150559-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "C195078T", - "A196604-" - ], - "OPG002": [ - "S207L" - ], - "OPG117": [ - "D263N" - ] - }, - "labels": { - "aa": "OPG002: S207L; OPG117: D263N" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI245", - "node_attrs": { - "div": 560, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI245" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP215265" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C84008T", - "-150551G", - "-150552A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C151204T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI302", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI302" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP355563" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A188349-" - ] - } - } - }, - { - "name": "MPXV_USA_2022_CT0002", - "node_attrs": { - "div": 558, - "author": { - "author": "Gigante,C.M., Pearson,C., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Maloney,M., Li,Y.", - "value": "Gigante,C.M., Pearson,C., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Maloney,M., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPXV_USA_2022_CT0002" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP451009" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "G150559-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "A173280-", - "T173281-", - "A173282-", - "T173283-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "T173297-", - "A173298-", - "T173299-", - "A173300-", - "T173301-", - "A173302-", - "T173303-", - "A173304-", - "T173305-", - "A173306-", - "T173307-", - "A173308-", - "T173309-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "A196604-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI470", - "node_attrs": { - "div": 560, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI470" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP626108" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G53788A", - "G107868A", - "-150551G", - "-150552A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T" - ], - "OPG126": [ - "S88F" - ] - }, - "labels": { - "aa": "OPG126: S88F" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI586", - "node_attrs": { - "div": 562, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI586" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP837348" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C2459T", - "G90418A", - "C133943T", - "C134688T", - "-150551G", - "-150552A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G194751A" - ], - "OPG002": [ - "R98Q" - ], - "OPG111": [ - "E52K" - ] - }, - "labels": { - "aa": "OPG002: R98Q; OPG111: E52K" - } - } - }, - { - "name": "NY-NYCPHL-000273", - "node_attrs": { - "div": 558, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-08-01" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "NY-NYCPHL-000273" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468471" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "G150559-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "NY-NYCPHL-000044", - "node_attrs": { - "div": 558, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-05-25" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "NY-NYCPHL-000044" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469021" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150558T", - "-150567A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI722", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI722" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ547749" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150551G", - "-150552A", - "-150558T", - "-150560G", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "Lesion", - "node_attrs": { - "div": 560, - "author": { - "author": "Pettke,A., Filen,F., Asgeirsson,H., Glans,H., Widgren,K., Muradrasoli,S., Helgesson,S., Karlberg,M.L., Walai,N., Bjerkner,A., Gourle,H., Lindsjo,O.K., Sonden,K.", - "value": "Pettke,A., Filen,F., Asgeirsson,H., Glans,H., Widgren,K., Muradrasoli,S., Helgesson,S., Karlberg,M.L., Walai,N., Bjerkner,A., Gourle,H., Lindsjo,O.K., Sonden,K." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Public Health Agency of Sweden, Unit for Laboratory Development and Technology Transfer , Folkhalsomyndigheten, 171 82 Solna" - }, - "date": { - "value": "2022-05-22" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "Lesion" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OX009124" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Sweden" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "T597-", - "T598-", - "T599-", - "T600-", - "A8048-", - "A28531-", - "A28532-", - "T47051-", - "T76079-", - "T88831-", - "A91698-", - "A92904-", - "T103362-", - "T104686-", - "T148344A", - "A148345T", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "G150559-", - "A151674-", - "A162901-", - "T163338-", - "T163592-", - "A170723-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "A196604-" - ], - "OPG044": [ - "K147X", - "M148X", - "*150X" - ], - "OPG066": [ - "K126X", - "*260X" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG109": [ - "K206X", - "*796X" - ], - "OPG113": [ - "K392X", - "*846X" - ], - "OPG123": [ - "T129X", - "N570X", - "*632X" - ], - "OPG178": [ - "K56X", - "*205X" - ], - "OPG188": [ - "K436X", - "*504X" - ], - "OPG189": [ - "D2X", - "I87X", - "*562X" - ], - "OPG198": [ - "Q229X", - "*283X" - ] - }, - "labels": { - "aa": "OPG044: K147X, M148X, *150X; OPG066: K126X, *260X; OPG097: K266X, *345X; OPG109: K206X, *796X; OPG113: K392X, *846X; OPG123: T129X, N570X, *632X; OPG178: K56X, *205X; OPG188: K436X, *504X; OPG189: D2X, I87X, *562X; OPG198: Q229X, *283X" - } - } - }, - { - "name": "NODE_0000193", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G28021A", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "G150559-" - ] - } - }, - "children": [ - { - "name": "MPX/Human/USA/CA-LACPHL-MA00137/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-08-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPX/Human/USA/CA-LACPHL-MA00137/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP539922" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G109793A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G168211-", - "G168212-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "G181818A" - ], - "OPG210": [ - "A155T" - ] - }, - "labels": { - "aa": "OPG210: A155T" - } - } - }, - { - "name": "MPXV/Human/USA/UT-UPHL-82200381/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Iverson,T., Oakeson,K.F., Young,E.L., Wagner,J., Hergert,J.", - "value": "Iverson,T., Oakeson,K.F., Young,E.L., Wagner,J., Hergert,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Utah Public Health Laboratory, Utah Public Health Laboratory Infectious Disease submission group" - }, - "date": { - "value": "2022-09-10" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPXV/Human/USA/UT-UPHL-82200381/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR026628" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C148666T" - ], - "OPG174": [ - "A244T" - ] - }, - "labels": { - "aa": "OPG174: A244T" - } - } - }, - { - "name": "MPXV/Human/USA/UT-UPHL-82200396/2022", - "node_attrs": { - "div": 563, - "author": { - "author": "Iverson,T., Oakeson,K.F., Young,E.L., Wagner,J., Hergert,J.", - "value": "Iverson,T., Oakeson,K.F., Young,E.L., Wagner,J., Hergert,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Utah Public Health Laboratory, Utah Public Health Laboratory Infectious Disease submission group" - }, - "date": { - "value": "2022-09-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPXV/Human/USA/UT-UPHL-82200396/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR026632" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C25855T", - "G127941A", - "C177833T", - "C177917T" - ], - "OPG042": [ - "E415K" - ], - "OPG150": [ - "D55N" - ] - }, - "labels": { - "aa": "OPG042: E415K; OPG150: D55N" - } - } - } - ] - }, - { - "name": "NODE_0000194", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G158617A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "C183790T" - ], - "OPG210": [ - "S812L" - ] - }, - "labels": { - "aa": "OPG210: S812L" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI558", - "node_attrs": { - "div": 561, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI558" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP764616" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C132437T", - "-150551G", - "-150552A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T179065-", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-" - ] - } - } - }, - { - "name": "NODE_0000195", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C22880T", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "G150559-", - "C170573T" - ], - "OPG038": [ - "E94K" - ], - "OPG198": [ - "S179L" - ] - }, - "labels": { - "aa": "OPG038: E94K; OPG198: S179L" - } - }, - "children": [ - { - "name": "MPXV/UZ_REGA_40", - "node_attrs": { - "div": 562, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-07-27" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_40" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035646" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/UZ_REGA_147/Belgium/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-07-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_147/Belgium/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR086956" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T149487-", - "A149488-", - "C149489-", - "G149490-", - "T149491-", - "T149492-", - "G149493-", - "A149494-", - "A149495-", - "C149496-", - "A149497-", - "A149498-", - "G149499-", - "T149500-", - "C149501-", - "C149502-", - "A149503-" - ], - "OPG175": [ - "Y16-", - "V17-", - "E18-", - "Q19-", - "V20-", - "H21X", - "*126X" - ] - }, - "labels": { - "aa": "OPG175: Y16-, V17-, E18-, Q19-, V20-, H21X, *126X" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000196", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C8552T", - "C8597T", - "G46179A", - "T150553-", - "A150554-", - "T150555-", - "A150557-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-" - ], - "OPG065": [ - "S102L" - ] - }, - "labels": { - "aa": "OPG065: S102L" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_TX0010", - "node_attrs": { - "div": 561, - "author": { - "author": "Gigante,C.M., Kubin,G., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S.L., Li,Y.", - "value": "Gigante,C.M., Kubin,G., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S.L., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPXV_USA_2022_TX0010" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP378704" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "-595T", - "G150556-", - "G150559-", - "C179145-", - "C179154-", - "-196602A", - "-196603A" - ] - } - } - }, - { - "name": "NODE_0000197", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C133557T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179137A", - "-179138T", - "-179139T", - "-179140A", - "-179141T", - "-179142A", - "-179143T", - "-179144A", - "-179146A", - "-179147T", - "-179148T", - "-179149A", - "-179150T", - "-179151A", - "-179152T", - "-179153A" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI346", - "node_attrs": { - "div": 563, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI346" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP484667" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C45361T" - ], - "OPG064": [ - "D180N" - ] - }, - "labels": { - "aa": "OPG064: D180N" - } - } - }, - { - "name": "NODE_0000198", - "node_attrs": { - "div": 564, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T63026G", - "T162919C" - ], - "OPG082": [ - "T143P" - ], - "OPG188": [ - "Y442H" - ] - }, - "labels": { - "aa": "OPG082: T143P; OPG188: Y442H" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI179", - "node_attrs": { - "div": 564, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI179" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP018604" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Germany/2022/RKI387", - "node_attrs": { - "div": 565, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI387" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP523989" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A15005G" - ], - "OPG025": [ - "L88S" - ] - }, - "labels": { - "aa": "OPG025: L88S" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000199", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G171270A", - "-196603A" - ], - "OPG199": [ - "D95N" - ] - }, - "labels": { - "aa": "OPG199: D95N" - } - }, - "children": [ - { - "name": "hMPXV-IHU00015", - "node_attrs": { - "div": 560, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "date": { - "value": "2022-07-22" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "hMPXV-IHU00015" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP382492" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G161913A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "T196584-", - "C196585-", - "A196586-" - ] - } - } - }, - { - "name": "hMPXV-IHU00016", - "node_attrs": { - "div": 562, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "date": { - "value": "2022-07-22" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "hMPXV-IHU00016" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP382493" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G25999A", - "G97417A", - "G100939A", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "A196603-" - ], - "OPG042": [ - "Q367*" - ], - "OPG117": [ - "E457K" - ] - }, - "labels": { - "aa": "OPG042: Q367*; OPG117: E457K" - } - } - }, - { - "name": "Monkeypox/PT0486/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "Monkeypox/PT0486/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555562" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150558T" - ] - } - } - }, - { - "name": "Monkeypox/PT0501/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-16" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "Monkeypox/PT0501/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555575" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150558T" - ] - } - } - }, - { - "name": "Monkeypox/PT0573/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-09-06" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "Monkeypox/PT0573/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555644" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594A", - "-595T", - "C93713T", - "-150551G", - "-150552A", - "-150558T", - "G158549A", - "-196601A", - "-196602A", - "A196616T" - ] - } - } - }, - { - "name": "Slovenia-MPXV-10-2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "Slovenia-MPXV-10-2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605553" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594A", - "-595T", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G196443-", - "A196444-", - "A196445-" - ] - } - } - }, - { - "name": "NY-NYCPHL-001139", - "node_attrs": { - "div": 559, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-07-06" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.14" - }, - "strain_original": { - "value": "NY-NYCPHL-001139" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468597" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T150544-", - "A150545-", - "T150546-", - "G150547-", - "A150548-", - "A150549-", - "G150550-", - "-150558A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000200", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C89906T", - "G94798A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG110": [ - "S92F" - ], - "OPG115": [ - "E47K" - ] - }, - "labels": { - "aa": "OPG110: S92F; OPG115: E47K", - "clade": "B.1.10" - } - }, - "children": [ - { - "name": "MpxV/Spain/MD-HGUGM-6513479/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Buenestado-Serrano,S., Palomino-Cabrera,R., Penas-Utrilla,D., Rodriguez-Grande,J., Sola Campoy,P., Perez-Lago,L., Rodriguez-Grande,C., Herranz Martin,M., Suarez,J., Catalan,P., Munoz,P., Garcia de Viedma,D.", - "value": "Buenestado-Serrano,S., Palomino-Cabrera,R., Penas-Utrilla,D., Rodriguez-Grande,J., Sola Campoy,P., Perez-Lago,L., Rodriguez-Grande,C., Herranz Martin,M., Suarez,J., Catalan,P., Munoz,P., Garcia de Viedma,D." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Microbial Genomics, Hospital General Universitario Gregorio Marañón, Madrid, Spain" - }, - "date": { - "value": "2022-05-27" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "MpxV/Spain/MD-HGUGM-6513479/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON720848" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A322-", - "T596-", - "T597-", - "A1691-", - "T4293-", - "T6583-", - "T6584-", - "T7248-", - "G7723-", - "T8011-", - "A8032-", - "T8494-", - "T9509-", - "A9864-", - "T10497-", - "A10908-", - "T11184-", - "C11751-", - "T11752-", - "C11754T", - "T11756C", - "T12121-", - "A15754-", - "A17083-", - "A18860-", - "T18861A", - "A19353-", - "T20660-", - "A21075-", - "T21971-", - "T24677-", - "T25851-", - "T26098-", - "C27001-", - "A27108-", - "C27798-", - "A28531-", - "A28532-", - "T32188-", - "T33409-", - "G35948-", - "T37976-", - "T39127-", - "T39861-", - "T41738-", - "T42989-", - "C43012-", - "G43199-", - "A43442-", - "T44116-", - "T44735-", - "G46761-", - "T48670-", - "A49130-", - "T49830-", - "A51019-", - "A52765-", - "A54964-", - "A55119-", - "T55557-", - "T56035-", - "T57069-", - "A57274-", - "A58644-", - "T61743-", - "A62034-", - "T63624-", - "A64726-", - "A64931-", - "A65531-", - "A65962-", - "T66777-", - "A66839-", - "A67161-", - "C68464-", - "T68479-", - "C68898-", - "G69145-", - "A69739-", - "G69767-", - "A71250-", - "G71358-", - "T75828-", - "A76072-", - "T76079-", - "T76080-", - "A76150-", - "A76151-", - "A76883-", - "A77254-", - "T77800-", - "T78059-", - "A79037-", - "A79177-", - "G79217-", - "C79533T", - "A79782-", - "G80949-", - "C82480-", - "T84843-", - "T88090-", - "T88831-", - "T88939-", - "A89100-", - "T90643-", - "T91125-", - "T91365-", - "A91579-", - "A91698-", - "T94789-", - "A95338-", - "A95573-", - "G95742-", - "G95818-", - "A97348-", - "A97477-", - "A97496-", - "A97695-", - "A98679-", - "T101449-", - "G101515-", - "T102434-", - "T103362-", - "T103363-", - "T104274-", - "T105355-", - "T106591-", - "T108593-", - "A113916-", - "T113946-", - "C114428-", - "T114514-", - "T114751-", - "T115122-", - "G115798-", - "A116008-", - "C116494-", - "T116958-", - "T121116-", - "T121117-", - "G121268-", - "C121544-", - "T124020-", - "T124747-", - "A125249-", - "A126564-", - "T126680-", - "A126711-", - "A127246-", - "A127747-", - "A132020-", - "A132021-", - "T133092-", - "T133093-", - "T133094-", - "T133095-", - "T133096-", - "T133097-", - "T133098-", - "T133099-", - "T133633-", - "T136777-", - "T137881-", - "A143045-", - "A143360-", - "T143474-", - "A144224-", - "T146127-", - "A147994-", - "A149723-", - "A150337-", - "T150532-", - "T150533-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G150577-", - "A150578-", - "T150579-", - "A150580-", - "T150581-", - "G150582-", - "A150583-", - "T150584-", - "G150620-", - "G150621-", - "A150622-", - "T150623-", - "A150624-", - "T150625-", - "G150626-", - "A150627-", - "T150628-", - "A150629-", - "T150859-", - "A151485-", - "A151506-", - "G151544-", - "A152668-", - "T152680-", - "A153355-", - "A153418-", - "A153514-", - "T154859-", - "T155417-", - "C156605-", - "C156606-", - "A157991-", - "T163494-", - "T163592-", - "A163954-", - "A165456-", - "A166737-", - "G167640-", - "A167964-", - "T168120-", - "A170723-", - "T170754-", - "T170897-", - "T170898-", - "T172087-", - "T172661-", - "G179035-", - "A179546-", - "A179945-", - "T180901-", - "G181049-", - "A181246-", - "C183531-", - "A183777-", - "T187080-", - "A190929-", - "A191010-", - "G191517-", - "A196604-", - "A196605-", - "T196883-", - "T197177-" - ], - "NBT03_gp052": [ - "L8X", - "Y60X", - "*130X" - ], - "NBT03_gp174": [ - "K174X", - "*177X" - ], - "NBT03_gp175": [ - "R155X", - "*438X" - ], - "OPG019": [ - "E48X", - "*143X" - ], - "OPG021": [ - "Q93X", - "*243X" - ], - "OPG022": [ - "K121X", - "*127X" - ], - "OPG023": [ - "I260X", - "K382R", - "E383X", - "G384X", - "I573X", - "*661X" - ], - "OPG036": [ - "K135X", - "*178X" - ], - "OPG037": [ - "I155X", - "*443X" - ], - "OPG040": [ - "M268X", - "*376X" - ], - "OPG042": [ - "E33X", - "T334X", - "K416X", - "*425X" - ], - "OPG043": [ - "G53X", - "*277X" - ], - "OPG044": [ - "K147X", - "M148X", - "*150X" - ], - "OPG054": [ - "H17X", - "*440X" - ], - "OPG056": [ - "K353X", - "*636X" - ], - "OPG057": [ - "N112X", - "I357X", - "*373X" - ], - "OPG061": [ - "K49X", - "*232X" - ], - "OPG063": [ - "S83X", - "L164X", - "G226X", - "I234X", - "*480X" - ], - "OPG064": [ - "K388X", - "I595X", - "*738X" - ], - "OPG066": [ - "P223X", - "*260X" - ], - "OPG068": [ - "I157X", - "A310X", - "L544X", - "*568X" - ], - "OPG070": [ - "K144X", - "*274X" - ], - "OPG071": [ - "C558X", - "*1007X" - ], - "OPG074": [ - "K19X", - "N364X", - "K523X", - "*666X" - ], - "OPG075": [ - "F75X", - "*109X" - ], - "OPG078": [ - "F56X", - "*74X" - ], - "OPG080": [ - "K92X", - "*772X" - ], - "OPG083": [ - "M365X", - "*424X" - ], - "OPG084": [ - "E2X", - "G70X", - "P270X", - "E414X", - "*677X" - ], - "OPG085": [ - "K18X", - "G23X", - "F457X", - "S565X", - "K585X", - "*592X" - ], - "OPG087": [ - "F14X", - "G97X", - "*221X" - ], - "OPG088": [ - "L33X", - "L42X", - "*125X" - ], - "OPG090": [ - "R24X", - "L60X", - "*64X" - ], - "OPG096": [ - "I81X", - "*93X" - ], - "OPG097": [ - "F242X", - "K266X", - "A268X", - "*345X" - ], - "OPG098": [ - "K119X", - "*252X" - ], - "OPG099": [ - "F46X", - "*129X" - ], - "OPG100": [ - "F18X", - "*153X" - ], - "OPG102": [ - "A31X", - "G45X", - "T150I", - "E233X", - "*334X" - ], - "OPG104": [ - "P24X", - "*134X" - ], - "OPG105": [ - "A452X", - "F1240X", - "*1287X" - ], - "OPG109": [ - "F116X", - "N170X", - "K206X", - "K453X", - "*796X" - ], - "OPG111": [ - "F127X", - "N287X", - "*315X" - ], - "OPG112": [ - "I40X", - "I111X", - "*147X" - ], - "OPG115": [ - "F44X", - "K227X", - "*234X" - ], - "OPG116": [ - "P71X", - "G128X", - "S153X", - "*219X" - ], - "OPG117": [ - "K434X", - "K477X", - "E483X", - "L549X", - "*786X" - ], - "OPG118": [ - "L78X", - "*638X" - ], - "OPG120": [ - "S78X", - "K100X", - "*305X" - ], - "OPG122": [ - "F3X", - "*249X" - ], - "OPG123": [ - "K266X", - "N570X", - "*632X" - ], - "OPG124": [ - "N205X", - "*288X" - ], - "OPG125": [ - "N355X", - "*552X" - ], - "OPG127": [ - "N78X", - "*225X" - ], - "OPG133": [ - "K192X", - "I316X", - "I395X", - "G423X", - "K584X", - "F594X", - "*711X" - ], - "OPG134": [ - "G17X", - "K87X", - "P249X", - "*293X" - ], - "OPG136": [ - "N877X", - "*892X" - ], - "OPG138": [ - "N6X", - "*191X" - ], - "OPG139": [ - "P34X", - "*71X" - ], - "OPG140": [ - "G68X", - "*91X" - ], - "OPG145": [ - "L25X", - "S267X", - "K435X", - "*493X" - ], - "OPG148": [ - "P193X", - "I232X", - "G242X", - "K421X", - "*427X" - ], - "OPG149": [ - "S17X", - "I184X", - "*188X" - ], - "OPG151": [ - "K1033X", - "*1165X" - ], - "OPG153": [ - "K297X", - "*510X" - ], - "OPG154": [ - "K57X", - "*111X" - ], - "OPG164": [ - "R90X", - "S195X", - "*229X" - ], - "OPG165": [ - "K237X", - "*269X" - ], - "OPG170": [ - "I218X", - "*222X" - ], - "OPG172": [ - "K190X", - "*197X" - ], - "OPG175": [ - "S94X", - "*126X" - ], - "OPG176": [ - "K177X", - "*241X" - ], - "OPG178": [ - "L12X", - "*205X" - ], - "OPG180": [ - "K222X", - "K243X", - "K275X", - "*560X" - ], - "OPG181": [ - "F150X", - "*335X" - ], - "OPG189": [ - "D54X", - "I87X", - "K208X", - "*562X" - ], - "OPG190": [ - "E112X", - "*318X" - ], - "OPG192": [ - "K3X", - "*183X" - ], - "OPG193": [ - "G103X", - "K211X", - "F263X", - "*268X" - ], - "OPG198": [ - "Q229X", - "T239X", - "*283X" - ], - "OPG208": [ - "Q94X", - "E227X", - "*358X" - ], - "OPG209": [ - "T128X", - "G178X", - "*191X" - ], - "OPG210": [ - "P726X", - "K808X", - "*1881X" - ] - }, - "labels": { - "aa": "NBT03_gp052: L8X, Y60X, *130X; NBT03_gp174: K174X, *177X; NBT03_gp175: R155X, *438X; OPG019: E48X, *143X; OPG021: Q93X, *243X; OPG022: K121X, *127X; OPG023: I260X, K382R, E383X, G384X, I573X, *661X; OPG036: K135X, *178X; OPG037: I155X, *443X; OPG040: M268X, *376X; OPG042: E33X, T334X, K416X, *425X; OPG043: G53X, *277X; OPG044: K147X, M148X, *150X; OPG054: H17X, *440X; OPG056: K353X, *636X; OPG057: N112X, I357X, *373X; OPG061: K49X, *232X; OPG063: S83X, L164X, G226X, I234X, *480X; OPG064: K388X, I595X, *738X; OPG066: P223X, *260X; OPG068: I157X, A310X, L544X, *568X; OPG070: K144X, *274X; OPG071: C558X, *1007X; OPG074: K19X, N364X, K523X, *666X; OPG075: F75X, *109X; OPG078: F56X, *74X; OPG080: K92X, *772X; OPG083: M365X, *424X; OPG084: E2X, G70X, P270X, E414X, *677X; OPG085: K18X, G23X, F457X, S565X, K585X, *592X; OPG087: F14X, G97X, *221X; OPG088: L33X, L42X, *125X; OPG090: R24X, L60X, *64X; OPG096: I81X, *93X; OPG097: F242X, K266X, A268X, *345X; OPG098: K119X, *252X; OPG099: F46X, *129X; OPG100: F18X, *153X; OPG102: A31X, G45X, T150I, E233X, *334X; OPG104: P24X, *134X; OPG105: A452X, F1240X, *1287X; OPG109: F116X, N170X, K206X, K453X, *796X; OPG111: F127X, N287X, *315X; OPG112: I40X, I111X, *147X; OPG115: F44X, K227X, *234X; OPG116: P71X, G128X, S153X, *219X; OPG117: K434X, K477X, E483X, L549X, *786X; OPG118: L78X, *638X; OPG120: S78X, K100X, *305X; OPG122: F3X, *249X; OPG123: K266X, N570X, *632X; OPG124: N205X, *288X; OPG125: N355X, *552X; OPG127: N78X, *225X; OPG133: K192X, I316X, I395X, G423X, K584X, F594X, *711X; OPG134: G17X, K87X, P249X, *293X; OPG136: N877X, *892X; OPG138: N6X, *191X; OPG139: P34X, *71X; OPG140: G68X, *91X; OPG145: L25X, S267X, K435X, *493X; OPG148: P193X, I232X, G242X, K421X, *427X; OPG149: S17X, I184X, *188X; OPG151: K1033X, *1165X; OPG153: K297X, *510X; OPG154: K57X, *111X; OPG164: R90X, S195X, *229X; OPG165: K237X, *269X; OPG170: I218X, *222X; OPG172: K190X, *197X; OPG175: S94X, *126X; OPG176: K177X, *241X; OPG178: L12X, *205X; OPG180: K222X, K243X, K275X, *560X; OPG181: F150X, *335X; OPG189: D54X, I87X, K208X, *562X; OPG190: E112X, *318X; OPG192: K3X, *183X; OPG193: G103X, K211X, F263X, *268X; OPG198: Q229X, T239X, *283X; OPG208: Q94X, E227X, *358X; OPG209: T128X, G178X, *191X; OPG210: P726X, K808X, *1881X" - } - } - }, - { - "name": "MPXV_UK_2022_9000103", - "node_attrs": { - "div": 558, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-06-13" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000103" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205091" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV_UK_2022_9000147", - "node_attrs": { - "div": 558, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-06-14" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000147" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205110" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPX/PT0081/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-07-23" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "MPX/PT0081/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP245334" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A590-", - "T591-", - "C120237T", - "G126047A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A196599-", - "C196600-", - "-196601A", - "-196603A" - ], - "OPG148": [ - "R21K" - ] - }, - "labels": { - "aa": "OPG148: R21K" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-28205C", - "node_attrs": { - "div": 563, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-10-13" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-28205C" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ261696" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C9389T", - "C13399T", - "G17339A", - "C49265T", - "A185557C", - "C190859T", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG210": [ - "K1401T" - ] - }, - "labels": { - "aa": "OPG210: K1401T" - } - } - }, - { - "name": "NY-NYCPHL-000145", - "node_attrs": { - "div": 559, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-06-27" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "NY-NYCPHL-000145" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ504404" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C15311T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150567T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV/Spain/HUNSC_ITER_0005b/2022", - "node_attrs": { - "div": 571, - "author": { - "author": "Munoz-Barrera,A., Ciuffreda,L., Alcoba-Florez,J., Rubio-Rodriguez,L.A., Rodriguez-Perez,H., Gil-Campesino,H., Garcia-Martinez de Artola,D., Salas-Hernandez,J., Rodriguez-Nunez,J., Inigo-Campos,A., Garcia-Olivares,V., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C.", - "value": "Munoz-Barrera,A., Ciuffreda,L., Alcoba-Florez,J., Rubio-Rodriguez,L.A., Rodriguez-Perez,H., Gil-Campesino,H., Garcia-Martinez de Artola,D., Salas-Hernandez,J., Rodriguez-Nunez,J., Inigo-Campos,A., Garcia-Olivares,V., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division" - }, - "date": { - "value": "2022-07-01" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "MPXV/Spain/HUNSC_ITER_0005b/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ581847" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A43453G", - "A66769C", - "T88735A", - "G90070A", - "C101656T", - "G104325A", - "C121681T", - "G127869A", - "G132490A", - "T133095A", - "-133168C", - "-133169T", - "-133170T", - "-133171T", - "-133173T", - "T139779C", - "G140866T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C151204T", - "T176743A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG063": [ - "L79P" - ], - "OPG085": [ - "V588G" - ], - "OPG109": [ - "E238V" - ], - "OPG110": [ - "D147N" - ], - "OPG123": [ - "A249V" - ], - "OPG150": [ - "G31R" - ], - "OPG160": [ - "S70Y" - ], - "OPG205": [ - "L363*" - ] - }, - "labels": { - "aa": "OPG063: L79P; OPG085: V588G; OPG109: E238V; OPG110: D147N; OPG123: A249V; OPG150: G31R; OPG160: S70Y; OPG205: L363*" - } - } - }, - { - "name": "NODE_0000201", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C33103T", - "C45605T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG049": [ - "E17K" - ] - }, - "labels": { - "aa": "OPG049: E17K" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI241", - "node_attrs": { - "div": 561, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI241" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP215226" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G47702A", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI885", - "node_attrs": { - "div": 560, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI885" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773504" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A41660-", - "A41661-", - "T41662-", - "T41663-", - "T41664-", - "G41665-", - "T41666-", - "T41667-", - "T41668-", - "T41669-", - "A41670-", - "C41671-", - "T41672-", - "C41673-", - "T41674-", - "A41675-", - "T41676-", - "A41677-", - "G150550-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T" - ], - "OPG061": [ - "Y70-", - "R71-", - "V72-", - "K73-", - "Q74-", - "I75-" - ] - }, - "labels": { - "aa": "OPG061: Y70-, R71-, V72-, K73-, Q74-, I75-" - } - } - } - ] - }, - { - "name": "NODE_0000202", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C20879T", - "C60094T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG036": [ - "M62I" - ], - "OPG080": [ - "R642K" - ] - }, - "labels": { - "aa": "OPG036: M62I; OPG080: R642K" - } - }, - "children": [ - { - "name": "MPX_Tga3e9_9000325", - "node_attrs": { - "div": 561, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "MPX_Tga3e9_9000325" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415264" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G86904A", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-" - ] - } - } - }, - { - "name": "NY-NYCPHL-000716", - "node_attrs": { - "div": 560, - "author": { - "author": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-07-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "NY-NYCPHL-000716" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468635" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T495C", - "T150544-", - "A150545-", - "T150546-", - "G150547-", - "A150548-", - "A150549-", - "G150550-", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558A", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A196715G" - ] - } - } - }, - { - "name": "NY-NYCPHL-000421", - "node_attrs": { - "div": 562, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-09-01" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "NY-NYCPHL-000421" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468985" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C156348T", - "A182480G" - ] - } - } - }, - { - "name": "NY-NYCPHL-000469", - "node_attrs": { - "div": 564, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-07-22" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "NY-NYCPHL-000469" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ504445" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C97334T", - "G99667A", - "T136555-", - "A136556-", - "T136557-", - "G136558-", - "A136559-", - "T136560-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150567T", - "C181957-", - "C181958-", - "A181959-", - "T181960-", - "G181961-", - "G181962-", - "T181963-", - "T181964-", - "G181965-", - "A181966-", - "T181967-", - "G181968-", - "A181969-", - "T181970-", - "G181971-", - "A181972-", - "G181973-", - "A181974-", - "C181975-", - "A181976-", - "T181977-", - "A181980G", - "C185326T" - ], - "OPG117": [ - "S429F" - ], - "OPG118": [ - "E408K" - ], - "OPG153": [ - "I370-", - "I371-" - ], - "OPG210": [ - "T201X", - "M202-", - "V203-", - "D204-", - "D205-", - "E206-", - "T207-", - "S208X", - "N209D", - "S1324L", - "*1881X" - ] - }, - "labels": { - "aa": "OPG117: S429F; OPG118: E408K; OPG153: I370-, I371-; OPG210: T201X, M202-, V203-, D204-, D205-, E206-, T207-, S208X, N209D, S1324L, *1881X" - } - } - } - ] - }, - { - "name": "NODE_0000203", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "C150831T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A" - ] - } - }, - "children": [ - { - "name": "MPX-96/Finland/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Kant,R., Smura,T., Vauhkonen,H., Vapalahti,O.", - "value": "Kant,R., Smura,T., Vauhkonen,H., Vapalahti,O." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Helsinki, Department of Virology, Faculty of Medicine" - }, - "date": { - "value": "2022-06-16" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "MPX-96/Finland/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON959143" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Finland" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "C188491T" - ] - } - } - }, - { - "name": "hMPXV-IHU00012", - "node_attrs": { - "div": 560, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "date": { - "value": "2022-07-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "hMPXV-IHU00012" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP382489" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G109437A", - "A136513-", - "T136514-", - "C136515-", - "A136516-", - "T136517-", - "C136518-", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G150568-", - "A150569-", - "T150570-", - "A150571-", - "T150572-", - "G150573-", - "A150574-", - "T150575-", - "G150576-", - "G150577-", - "A150578-", - "T150579-", - "A150580-", - "T150581-", - "G150582-", - "A150583-", - "T150584-", - "G150585-", - "A150586-", - "T150587-", - "A150588-", - "T150589-", - "G150590-", - "A150591-", - "T150592-", - "G150593-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-" - ], - "OPG129": [ - "S523L" - ], - "OPG153": [ - "D384-", - "D385-" - ] - }, - "labels": { - "aa": "OPG129: S523L; OPG153: D384-, D385-" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI373", - "node_attrs": { - "div": 559, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI373" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP484694" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI606", - "node_attrs": { - "div": 559, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI606" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP863256" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "A150552-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "G181049-" - ], - "OPG209": [ - "G178X", - "*191X" - ] - }, - "labels": { - "aa": "OPG209: G178X, *191X" - } - } - }, - { - "name": "NY-NYCPHL-001041", - "node_attrs": { - "div": 559, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-06-26" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "NY-NYCPHL-001041" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469234" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - } - ] - }, - { - "name": "NODE_0000204", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G50672A" - ], - "OPG070": [ - "R28K" - ] - }, - "labels": { - "aa": "OPG070: R28K" - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-25285O", - "node_attrs": { - "div": 559, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-09-13" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-25285O" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP642408" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "ANT_INS_MPX_0024_L", - "node_attrs": { - "div": 560, - "author": { - "author": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M.", - "value": "Laiton-Donato,K., Alvarez-Diaz,D.A., Franco-Munoz,C., Ruiz-Moreno,H.A., Rojas-Estevez,P., Rosales,A., Martinez,D., Flores,A., Prieto,F., Walteros,D., Gomez,S., Mercado-Reyes,M." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica" - }, - "date": { - "value": "2022-08-07" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "ANT_INS_MPX_0024_L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP693650" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G93624A" - ], - "OPG113": [ - "E632K" - ] - }, - "labels": { - "aa": "OPG113: E632K" - } - } - }, - { - "name": "LBMB-UTP_MP-002_TOL", - "node_attrs": { - "div": 559, - "author": { - "author": "Anacona,J.D., Lopez,P.A., Orjuela,M., Tabares,F.A., Zuluaga-Velez,A., Sepulveda-Arias,J.C.", - "value": "Anacona,J.D., Lopez,P.A., Orjuela,M., Tabares,F.A., Zuluaga-Velez,A., Sepulveda-Arias,J.C." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud" - }, - "date": { - "value": "2022-09-17" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "LBMB-UTP_MP-002_TOL" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ148461" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "LBMB-UTP_MP-011_VAC", - "node_attrs": { - "div": 561, - "author": { - "author": "Orjuela,M., Tabares,F.A., Anacona,J.D., Lopez,P.A., Zuluaga-Velez,A., Sepulveda-Arias,J.C.", - "value": "Orjuela,M., Tabares,F.A., Anacona,J.D., Lopez,P.A., Zuluaga-Velez,A., Sepulveda-Arias,J.C." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud" - }, - "date": { - "value": "2022-09-11" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "LBMB-UTP_MP-011_VAC" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ148470" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C25087T", - "C62649T" - ], - "OPG040": [ - "R131K" - ] - }, - "labels": { - "aa": "OPG040: R131K" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-28290C", - "node_attrs": { - "div": 560, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-10-13" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-28290C" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ261701" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G68499A", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "A173278-", - "T173279-", - "T195509-", - "A195510-", - "A195511-" - ] - } - } - }, - { - "name": "NODE_0000205", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C49265T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-23654-O", - "node_attrs": { - "div": 563, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia" - }, - "date": { - "value": "2022-08-30" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-23654-O" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP459217" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C113965T", - "G150800A", - "C152191T", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ], - "OPG133": [ - "E578K" - ] - }, - "labels": { - "aa": "OPG133: E578K" - } - } - }, - { - "name": "9000385", - "node_attrs": { - "div": 561, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "9000385" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536764" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C100007T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A196604-" - ], - "OPG118": [ - "S521F" - ] - }, - "labels": { - "aa": "OPG118: S521F" - } - } - } - ] - }, - { - "name": "NODE_0000206", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C13624T" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/ON/RKI511", - "node_attrs": { - "div": 561, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-10-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI511" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP689664" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C43472T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T" - ], - "OPG063": [ - "E73K" - ] - }, - "labels": { - "aa": "OPG063: E73K" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-28769E", - "node_attrs": { - "div": 562, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-10-21" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-28769E" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ261710" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G164476A", - "G176289A", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG189": [ - "E382K" - ], - "OPG205": [ - "A212T" - ] - }, - "labels": { - "aa": "OPG189: E382K; OPG205: A212T" - } - } - } - ] - }, - { - "name": "NODE_0000207", - "node_attrs": { - "div": 564, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A577-", - "A578-", - "A579-", - "G32863A", - "G45416A", - "C72770T", - "C123118T", - "C148771T", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-", - "A196376-", - "T196377-", - "C196378-" - ], - "OPG092": [ - "E60K" - ], - "OPG174": [ - "D209N" - ] - }, - "labels": { - "aa": "OPG092: E60K; OPG174: D209N" - } - }, - "children": [ - { - "name": "ANT-LDSP-ANT-MPX-30513C", - "node_attrs": { - "div": 567, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-11-10" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-30513C" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ696098" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A50672G", - "C67823T", - "A94798G" - ], - "OPG070": [ - "K28R" - ], - "OPG085": [ - "E237K" - ], - "OPG115": [ - "K47E" - ] - }, - "labels": { - "aa": "OPG070: K28R; OPG085: E237K; OPG115: K47E" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-31501C", - "node_attrs": { - "div": 564, - "author": { - "author": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde Hoyos,C.A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-11-22" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.10" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-31501C" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ696103" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000208", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G5595A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C191615T" - ], - "NBT03_gp175": [ - "Q188*" - ], - "OPG015": [ - "Q188*" - ] - }, - "labels": { - "aa": "NBT03_gp175: Q188*; OPG015: Q188*", - "clade": "B.1.8" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI235", - "node_attrs": { - "div": 557, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI235" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP215224" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "NODE_0000209", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G78034A", - "C80111T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG099": [ - "D124N" - ] - }, - "labels": { - "aa": "OPG099: D124N" - } - }, - "children": [ - { - "name": "MPXV/ES0001/HUGTiP/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Martinez-Puchol,S., Coello,A., Bordoy,A.E., Soler,L., Panisello,D., Gonzalez-Gomez,S., Clara,G., Paris de Leon,A., Not,A., Hernandez,A., Bofill-Mas,S., Saludes,V., Blanco,I., Martro,E., Cardona,P.-J.", - "value": "Martinez-Puchol,S., Coello,A., Bordoy,A.E., Soler,L., Panisello,D., Gonzalez-Gomez,S., Clara,G., Paris de Leon,A., Not,A., Hernandez,A., Bofill-Mas,S., Saludes,V., Blanco,I., Martro,E., Cardona,P.-J." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Microbiology, Hospital Universitari Germans Trias i Pujol, Spain" - }, - "date": { - "value": "2022-05-20" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MPXV/ES0001/HUGTiP/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON622718" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C14113-", - "-133164C", - "-133165A", - "-133166A", - "-133167T", - "-133168C", - "-133169T", - "-133170T", - "-133171T", - "-133172C", - "-133173T", - "T139150C", - "A178796-", - "T178797-", - "G178798-", - "G178799-", - "G178800-", - "A178801-", - "A178802-", - "T178803-", - "T178804-", - "G178805-", - "G178806-", - "T178807-", - "A178808-", - "A178809-", - "C178810-", - "G178811-", - "A178812-", - "T178813-", - "G178814-", - "A178815-", - "C178816-", - "A178817-", - "G178818-", - "A178819-", - "A178820-", - "A178821-", - "G178822-", - "C178823-", - "A178824-", - "G178825-", - "A178826-", - "T178827-", - "T178828-", - "G178829-", - "T178830-", - "C178831-", - "A178832-", - "G178833-", - "C178834-", - "T178835-", - "C178836-", - "T178837-", - "G178838-", - "C178839-", - "A178840-", - "T178841-", - "A178842-", - "C178843-", - "T178844-", - "A178845-", - "T178846-", - "T178847-", - "C178848-", - "T178849-", - "T178850-", - "C178851-", - "A178852-", - "T178853-", - "G178854-", - "A178855-", - "C178856-", - "A178857-", - "A178858-", - "T178859-", - "A178860-", - "C178861-", - "C178862-", - "A178863-", - "T178864-", - "A178865-", - "A178866-", - "T178867-", - "G178868-", - "A178869-", - "T178870-", - "G178871-", - "T178872-", - "T178873-", - "A178874-", - "C178875-", - "A178876-", - "T178877-", - "T178878-", - "G178879-", - "T178880-", - "T178881-", - "A178882-", - "T178883-", - "G178884-", - "A178885-", - "A178886-", - "G178887-", - "C178888-", - "G178889-", - "T178890-", - "A178891-", - "T178892-", - "-196602A", - "-196603A" - ], - "OPG025": [ - "E385X", - "*631X" - ], - "OPG156": [ - "Q87R" - ] - }, - "labels": { - "aa": "OPG025: E385X, *631X; OPG156: Q87R" - } - } - }, - { - "name": "MpxV/Spain/MD-HGUGM-6532064/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Buenestado-Serrano,S., Palomino-Cabrera,R., Penas-Utrilla,D., Rodriguez-Grande,J., Sola Campoy,P., Perez-Lago,L., Rodriguez-Grande,C., Herranz Martin,M., Suarez,J., Catalan,P., Munoz,P., Garcia de Viedma,D.", - "value": "Buenestado-Serrano,S., Palomino-Cabrera,R., Penas-Utrilla,D., Rodriguez-Grande,J., Sola Campoy,P., Perez-Lago,L., Rodriguez-Grande,C., Herranz Martin,M., Suarez,J., Catalan,P., Munoz,P., Garcia de Viedma,D." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Microbial Genomics, Hospital General Universitario Gregorio Marañón, Madrid, Spain" - }, - "date": { - "value": "2022-05-27" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MpxV/Spain/MD-HGUGM-6532064/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON720849" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A322-", - "T596-", - "T597-", - "T598-", - "A1691-", - "A8048-", - "A9523-", - "C11747-", - "T15122-", - "T16095-", - "A19353-", - "A21075-", - "A27108-", - "A28531-", - "A28532-", - "A28596-", - "T32188-", - "A33193-", - "T34040-", - "T35565-", - "T37976-", - "T39127-", - "T39861-", - "T41738-", - "A43502-", - "T43503-", - "C43504T", - "T43505C", - "T46643-", - "A55119-", - "T56035-", - "A57274-", - "A58644-", - "A62034-", - "T64749-", - "A64931-", - "G69145-", - "A69739-", - "T76079-", - "T76080-", - "A76883-", - "A79177-", - "T79226-", - "A79457-", - "A79782-", - "T80841-", - "T88090-", - "T88831-", - "A89100-", - "A91698-", - "T94640-", - "T94789-", - "A98077-", - "T103362-", - "T105355-", - "T108710-", - "A110973-", - "T114514-", - "T114751-", - "A116008-", - "T116958-", - "T121116-", - "C122649T", - "A123988-", - "A124720-", - "A127246-", - "A127747-", - "A128927-", - "A132020-", - "A132021-", - "T133094-", - "T133095-", - "T133096-", - "T133097-", - "T133098-", - "T133099-", - "T133633-", - "T137881-", - "A138468-", - "A142462-", - "A144224-", - "A147994-", - "T148337-", - "T150532-", - "G150577-", - "A150578-", - "T150579-", - "A150580-", - "T150581-", - "G150582-", - "A150583-", - "T150584-", - "G150620-", - "G150621-", - "A150622-", - "T150623-", - "A150624-", - "T150625-", - "G150626-", - "A150627-", - "T150628-", - "A150629-", - "A151980-", - "A152668-", - "T152680-", - "A153418-", - "A154123-", - "T155417-", - "A157991-", - "T163592-", - "T168120-", - "A168956-", - "A170723-", - "T170897-", - "T172087-", - "T172661-", - "T178041-", - "A179945-", - "G181049-", - "A181246-", - "A182643-", - "T187080-", - "A190929-", - "T195513-", - "A196588-", - "A196604-", - "A196605-", - "A196606-", - "A196607-", - "T197177-" - ], - "NBT03_gp052": [ - "L8X", - "*130X" - ], - "NBT03_gp174": [ - "K174X", - "*177X" - ], - "OPG023": [ - "G385X", - "*661X" - ], - "OPG025": [ - "N49X", - "*631X" - ], - "OPG027": [ - "T95X", - "*151X" - ], - "OPG044": [ - "K147X", - "M148X", - "*150X" - ], - "OPG050": [ - "F72X", - "*76X" - ], - "OPG054": [ - "K144X", - "*440X" - ], - "OPG056": [ - "K353X", - "*636X" - ], - "OPG057": [ - "N112X", - "I357X", - "*373X" - ], - "OPG061": [ - "K49X", - "*232X" - ], - "OPG063": [ - "R62X", - "F63X", - "*480X" - ], - "OPG074": [ - "N364X", - "*666X" - ], - "OPG075": [ - "F75X", - "*109X" - ], - "OPG078": [ - "F56X", - "*74X" - ], - "OPG084": [ - "F10X", - "G70X", - "*677X" - ], - "OPG087": [ - "G97X", - "*221X" - ], - "OPG088": [ - "L42X", - "*125X" - ], - "OPG097": [ - "K266X", - "*345X" - ], - "OPG102": [ - "A31X", - "F48X", - "K125X", - "E233X", - "*334X" - ], - "OPG104": [ - "N60X", - "*134X" - ], - "OPG109": [ - "F116X", - "K206X", - "K453X", - "*796X" - ], - "OPG114": [ - "I10X", - "*147X" - ], - "OPG115": [ - "F44X", - "*234X" - ], - "OPG117": [ - "K677X", - "*786X" - ], - "OPG123": [ - "N570X", - "*632X" - ], - "OPG124": [ - "N205X", - "*288X" - ], - "OPG127": [ - "K39X", - "*225X" - ], - "OPG129": [ - "L11X", - "*645X" - ], - "OPG133": [ - "I316X", - "I395X", - "*711X" - ], - "OPG134": [ - "K87X", - "*293X" - ], - "OPG136": [ - "N877X", - "*892X" - ], - "OPG138": [ - "N6X", - "*191X" - ], - "OPG143": [ - "D223N" - ], - "OPG145": [ - "L14X", - "L258X", - "*493X" - ], - "OPG148": [ - "K421X", - "*427X" - ], - "OPG149": [ - "S17X", - "I184X", - "*188X" - ], - "OPG150": [ - "*383X" - ], - "OPG151": [ - "K2X", - "K1033X", - "*1165X" - ], - "OPG154": [ - "K57X", - "*111X" - ], - "OPG155": [ - "F8X", - "*147X" - ], - "OPG163": [ - "S87X", - "*177X" - ], - "OPG165": [ - "K237X", - "*269X" - ], - "OPG172": [ - "K190X", - "*197X" - ], - "OPG178": [ - "K158X", - "*205X" - ], - "OPG180": [ - "K243X", - "K478X", - "*560X" - ], - "OPG189": [ - "I87X", - "*562X" - ], - "OPG193": [ - "F263X", - "*268X" - ], - "OPG198": [ - "Q229X", - "*283X" - ], - "OPG208": [ - "E227X", - "*358X" - ], - "OPG209": [ - "G178X", - "*191X" - ], - "OPG210": [ - "K430X", - "*1881X" - ] - }, - "labels": { - "aa": "NBT03_gp052: L8X, *130X; NBT03_gp174: K174X, *177X; OPG023: G385X, *661X; OPG025: N49X, *631X; OPG027: T95X, *151X; OPG044: K147X, M148X, *150X; OPG050: F72X, *76X; OPG054: K144X, *440X; OPG056: K353X, *636X; OPG057: N112X, I357X, *373X; OPG061: K49X, *232X; OPG063: R62X, F63X, *480X; OPG074: N364X, *666X; OPG075: F75X, *109X; OPG078: F56X, *74X; OPG084: F10X, G70X, *677X; OPG087: G97X, *221X; OPG088: L42X, *125X; OPG097: K266X, *345X; OPG102: A31X, F48X, K125X, E233X, *334X; OPG104: N60X, *134X; OPG109: F116X, K206X, K453X, *796X; OPG114: I10X, *147X; OPG115: F44X, *234X; OPG117: K677X, *786X; OPG123: N570X, *632X; OPG124: N205X, *288X; OPG127: K39X, *225X; OPG129: L11X, *645X; OPG133: I316X, I395X, *711X; OPG134: K87X, *293X; OPG136: N877X, *892X; OPG138: N6X, *191X; OPG143: D223N; OPG145: L14X, L258X, *493X; OPG148: K421X, *427X; OPG149: S17X, I184X, *188X; OPG150: *383X; OPG151: K2X, K1033X, *1165X; OPG154: K57X, *111X; OPG155: F8X, *147X; OPG163: S87X, *177X; OPG165: K237X, *269X; OPG172: K190X, *197X; OPG178: K158X, *205X; OPG180: K243X, K478X, *560X; OPG189: I87X, *562X; OPG193: F263X, *268X; OPG198: Q229X, *283X; OPG208: E227X, *358X; OPG209: G178X, *191X; OPG210: K430X, *1881X" - } - } - }, - { - "name": "NODE_0000210", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G22643A", - "G63811A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG038": [ - "H173Y" - ] - }, - "labels": { - "aa": "OPG038: H173Y" - } - }, - "children": [ - { - "name": "ATL-UNIMOL-MPX-292895-L", - "node_attrs": { - "div": 561, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "date": { - "value": "2022-08-12" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "ATL-UNIMOL-MPX-292895-L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP390176" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-23267-O", - "node_attrs": { - "div": 561, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-08-23" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-23267-O" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP477454" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI497", - "node_attrs": { - "div": 563, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI497" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP626136" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C64635T", - "G141114A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-" - ], - "OPG083": [ - "A28T" - ], - "OPG161": [ - "E5K" - ] - }, - "labels": { - "aa": "OPG083: A28T; OPG161: E5K" - } - } - }, - { - "name": "ANT-LDSP-ANT-MPX-24722-L", - "node_attrs": { - "div": 562, - "author": { - "author": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R.", - "value": "Betancur,I.I.B., Velarde-Hoyos,C.-A.C.V., Gomez,R.R.G., Mercado-Reyes,M.M.R." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Laboratorio Departamental de Salud Publica de Antioquia, Antioquia" - }, - "date": { - "value": "2022-09-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "ANT-LDSP-ANT-MPX-24722-L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP642374" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G168759A", - "T178536-", - "A178537-", - "T178538-", - "A178539-", - "A178540-", - "G178541-", - "C178542-", - "G178543-", - "G178544-", - "T178545-", - "C178546-", - "G178547-", - "T178548-", - "A178549-", - "C178550-", - "C178551-", - "C178552-", - "A178553-" - ], - "OPG195": [ - "R177K" - ] - }, - "labels": { - "aa": "OPG195: R177K" - } - } - }, - { - "name": "MPXV_USA_2022_FL0009", - "node_attrs": { - "div": 565, - "author": { - "author": "Gigante,C., Lee,P., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Stanek,D., Li,Y.", - "value": "Gigante,C., Lee,P., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Stanek,D., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-10-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MPXV_USA_2022_FL0009" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ320513" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G4038A", - "A39081T", - "C67289T", - "G73790A", - "T133099-", - "A173284-", - "T173285-", - "A173286-", - "T173287-", - "A173288-", - "T173289-", - "A173290-", - "T173291-", - "A173292-", - "T173293-", - "A173294-", - "T173295-", - "A173296-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "C193172T" - ], - "OPG057": [ - "I372N" - ], - "OPG085": [ - "E415K" - ], - "OPG094": [ - "G4E" - ] - }, - "labels": { - "aa": "OPG057: I372N; OPG085: E415K; OPG094: G4E" - } - } - }, - { - "name": "NY-NYCPHL-000324", - "node_attrs": { - "div": 566, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-08-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "NY-NYCPHL-000324" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468482" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C25624T", - "G61965A", - "G75127A", - "C147558T", - "G171939A" - ], - "OPG095": [ - "E109K" - ], - "OPG199": [ - "D318N" - ] - }, - "labels": { - "aa": "OPG095: E109K; OPG199: D318N" - } - } - }, - { - "name": "NY-NYCPHL-000979", - "node_attrs": { - "div": 561, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-07-11" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "NY-NYCPHL-000979" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468545" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T150544-", - "A150545-", - "T150546-", - "G150547-", - "A150548-", - "A150549-", - "G150550-", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558A", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "NY-NYCPHL-000710", - "node_attrs": { - "div": 568, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-07-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "NY-NYCPHL-000710" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468758" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C10856T", - "G27167A", - "G34702A", - "C51873T", - "G82317A", - "C127215T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C189713T" - ], - "OPG022": [ - "M1I" - ], - "OPG054": [ - "S432L" - ], - "OPG071": [ - "E856K" - ], - "OPG105": [ - "E398K" - ], - "OPG149": [ - "S7L" - ] - }, - "labels": { - "aa": "OPG022: M1I; OPG054: S432L; OPG071: E856K; OPG105: E398K; OPG149: S7L" - } - } - }, - { - "name": "NY-NYCPHL-000242", - "node_attrs": { - "div": 561, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-06-27" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "NY-NYCPHL-000242" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469178" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000211", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T119985C", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-" - ] - } - }, - "children": [ - { - "name": "MPX_imBNaw_9000300", - "node_attrs": { - "div": 563, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MPX_imBNaw_9000300" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415254" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G189258A" - ] - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-092889/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-092889/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP681774" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/USA/WA-UW-098497/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-098497/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP681775" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A136513-", - "T136514-", - "C136515-" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000212", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G161296A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI177", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI177" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP018602" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "MPXV_UK_2022_9000183", - "node_attrs": { - "div": 558, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-06-29" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000183" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP331337" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G902A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "C196308T" - ], - "OPG001": [ - "S225L" - ] - }, - "labels": { - "aa": "OPG001: S225L" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI321", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI321" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP355577" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "A188349-" - ] - } - } - }, - { - "name": "NY-NYCPHL-000150", - "node_attrs": { - "div": 558, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-06-29" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "NY-NYCPHL-000150" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469154" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G902A", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "C196308T" - ], - "OPG001": [ - "S225L" - ] - }, - "labels": { - "aa": "OPG001: S225L" - } - } - }, - { - "name": "NODE_0000213", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C186220T" - ], - "OPG210": [ - "A1622V" - ] - }, - "labels": { - "aa": "OPG210: A1622V" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI152", - "node_attrs": { - "div": 559, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI152" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON959166" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI459", - "node_attrs": { - "div": 561, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI459" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP615338" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G89716A", - "G128858A", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T" - ], - "OPG110": [ - "E29K" - ] - }, - "labels": { - "aa": "OPG110: E29K" - } - } - } - ] - }, - { - "name": "NODE_0000214", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C4648T", - "C172765T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "G192562A" - ] - } - }, - "children": [ - { - "name": "Monkeypox/PT0508/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-16" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "Monkeypox/PT0508/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555581" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0521/2022", - "node_attrs": { - "div": 563, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "Monkeypox/PT0521/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555592" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G44075A", - "A146877T", - "T146880A", - "C165621T", - "C187359T" - ], - "OPG190": [ - "S167L" - ] - }, - "labels": { - "aa": "OPG190: S167L" - } - } - } - ] - }, - { - "name": "NODE_0000215", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G902A", - "C68981T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "C196308T" - ], - "OPG001": [ - "S225L" - ], - "OPG087": [ - "S42L" - ] - }, - "labels": { - "aa": "OPG001: S225L; OPG087: S42L" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-080247/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-080247/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP628437" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G94092A", - "G172483A", - "C185731T", - "-196603A" - ], - "OPG113": [ - "D788N" - ], - "OPG200": [ - "A112T" - ], - "OPG210": [ - "S1459L" - ] - }, - "labels": { - "aa": "OPG113: D788N; OPG200: A112T; OPG210: S1459L" - } - } - }, - { - "name": "MPXV/UZ_REGA_17", - "node_attrs": { - "div": 559, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Sinnesael,R., Ysebaert,L., Verlinden,J., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-07-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_17" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR030928" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - } - ] - }, - { - "name": "NODE_0000216", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G2039A", - "G34298T", - "C37048T", - "G70190A", - "A146964-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "A150557-", - "T150558-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG089": [ - "E109K" - ] - }, - "labels": { - "aa": "OPG089: E109K" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/ON/RKI703", - "node_attrs": { - "div": 563, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI703" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ417837" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C11747-", - "-146964A", - "G150550-", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "T179047-", - "A179048-", - "A179049-", - "A179050-", - "C179051-", - "T179052-", - "G179053-", - "A179054-", - "A179055-", - "G179056-", - "T179057-", - "T179058-", - "T179059-", - "A179060-", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "G187156A" - ], - "OPG023": [ - "G385X", - "*661X" - ] - }, - "labels": { - "aa": "OPG023: G385X, *661X" - } - } - }, - { - "name": "MPXV/UZ_REGA_224/Belgium/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logis,A.-S., Bloemen,M., Van Holm,B., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logis,A.-S., Bloemen,M., Van Holm,B., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-08-12" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_224/Belgium/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR095042" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "G150556-", - "G150559-" - ] - } - } - } - ] - }, - { - "name": "NODE_0000217", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C80545T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG103": [ - "S182L" - ] - }, - "labels": { - "aa": "OPG103: S182L" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI540", - "node_attrs": { - "div": 560, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI540" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP715820" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G105792A" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI585", - "node_attrs": { - "div": 559, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI585" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP837347" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000218", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G102614A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "C170573T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG122": [ - "V63I" - ], - "OPG198": [ - "S179L" - ] - }, - "labels": { - "aa": "OPG122: V63I; OPG198: S179L" - } - }, - "children": [ - { - "name": "MPXV/UZ_REGA_108", - "node_attrs": { - "div": 561, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-10-28" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_108" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035714" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T195509-", - "A195510-", - "A195511-" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_185/Belgium/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-08-03" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.8" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_185/Belgium/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR086994" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000233", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C70780T", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - }, - "labels": { - "clade": "B.1.5" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI027", - "node_attrs": { - "div": 557, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI027" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON755233" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G" - ] - } - } - }, - { - "name": "INMI-Pt4", - "node_attrs": { - "div": 557, - "author": { - "author": "Gramigna,G., Giombini,E., Gruber,C.E.M., Rueca,M., Carletti,F., Cicalini,S., Lapa,D., Puro,V., Marani,A., Fabeni,L., Butera,O., Colavita,F., Meschi,S., Matusali,G., Rivano Capparuccia,M., Specchiarello,E., Vairo,F., Vaia,F., Nicastri,E., Antinori,A., Girardi,E., Maggi,F.", - "value": "Gramigna,G., Giombini,E., Gruber,C.E.M., Rueca,M., Carletti,F., Cicalini,S., Lapa,D., Puro,V., Marani,A., Fabeni,L., Butera,O., Colavita,F., Meschi,S., Matusali,G., Rivano Capparuccia,M., Specchiarello,E., Vairo,F., Vaia,F., Nicastri,E., Antinori,A., Girardi,E., Maggi,F." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology" - }, - "date": { - "value": "2022-05-21" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "INMI-Pt4" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON780017" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Italy" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A150566-", - "T150567-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-" - ] - } - } - }, - { - "name": "hMpxV/Switzerland/ZH-UZH-IMV-3ba64538/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Kufner,V., Ziltener,G., Zaheri,M., Schmutz,S., Audige,A., Bernasconi,O., Steiner,K., Huder,J., Shah,C., Capaul,R., Bloemberg,G., Boeni,J., Huber,M., Trkola,A.", - "value": "Kufner,V., Ziltener,G., Zaheri,M., Schmutz,S., Audige,A., Bernasconi,O., Steiner,K., Huder,J., Shah,C., Capaul,R., Bloemberg,G., Boeni,J., Huber,M., Trkola,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Zurich, Institute of Medical Virology" - }, - "date": { - "value": "2022-06-02" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "hMpxV/Switzerland/ZH-UZH-IMV-3ba64538/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON792322" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Switzerland" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A150566-", - "T150567-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C" - ] - } - } - }, - { - "name": "MPXV/human/Taiwan/110-231642/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MPXV/human/Taiwan/110-231642/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON918656" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Taiwan" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C28702T", - "T34793C", - "T50861C", - "C51777T", - "A150566-", - "T150567-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C" - ], - "OPG054": [ - "T402A" - ], - "OPG070": [ - "V91A" - ], - "OPG071": [ - "E888K" - ] - }, - "labels": { - "aa": "OPG054: T402A; OPG070: V91A; OPG071: E888K" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI137", - "node_attrs": { - "div": 557, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI137" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON959154" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI162", - "node_attrs": { - "div": 557, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI162" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON959175" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G" - ] - } - } - }, - { - "name": "MPXV_USA_2022_GA001", - "node_attrs": { - "div": 557, - "author": { - "author": "Gigante,C., Xia,D., Seabolt,M., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Plipat,N., Li,Y.", - "value": "Gigante,C., Xia,D., Seabolt,M., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Plipat,N., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MPXV_USA_2022_GA001" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP150925" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A150566-", - "T150567-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "Monkeypox/PT0244/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-06-21" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "Monkeypox/PT0244/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP414288" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-196603A" - ] - } - } - }, - { - "name": "hMPXV-CH-38347314/2022", - "node_attrs": { - "div": 558, - "author": { - "author": "Laubscher,F., Marques-Melancia,S., Cordey,S., Schibler,M., Kaiser,L., Renzoni,A.", - "value": "Laubscher,F., Marques-Melancia,S., Cordey,S., Schibler,M., Kaiser,L., Renzoni,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University Hospitals of Geneva, Laboratory of Virology" - }, - "date": { - "value": "2022-06-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "hMPXV-CH-38347314/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP783902" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Switzerland" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A150566-", - "T150567-", - "A173472G", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI662", - "node_attrs": { - "div": 557, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI662" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ274881" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A150566-", - "T150567-", - "A152668-", - "T152680-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI665", - "node_attrs": { - "div": 557, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI665" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ274884" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150565G", - "A152668-", - "T152680-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI857", - "node_attrs": { - "div": 557, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI857" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773476" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A" - ] - } - } - }, - { - "name": "Monkeypox/PT0033/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-05-24" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "Monkeypox/PT0033/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON843165" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI223", - "node_attrs": { - "div": 557, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI223" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP215219" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G" - ] - } - } - }, - { - "name": "NODE_0000235", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C133867T", - "C134247T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G" - ] - } - }, - "children": [ - { - "name": "MPX/PT0064/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-01" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MPX/PT0064/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP245318" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G71227A", - "G158866A" - ], - "OPG090": [ - "E17K" - ] - }, - "labels": { - "aa": "OPG090: E17K" - } - } - }, - { - "name": "Monkeypox/PT0527/2022", - "node_attrs": { - "div": 565, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "Monkeypox/PT0527/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555598" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G5876A", - "C87141T", - "C126707T", - "C128030T", - "C128417T", - "C187128T", - "C191334T" - ], - "NBT03_gp175": [ - "S94F" - ], - "OPG015": [ - "S94F" - ], - "OPG148": [ - "S241L" - ] - }, - "labels": { - "aa": "NBT03_gp175: S94F; OPG015: S94F; OPG148: S241L" - } - } - } - ] - }, - { - "name": "NODE_0000236", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A550-", - "T551-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "G159001A", - "C196435-", - "G196436-" - ], - "OPG185": [ - "D29N" - ] - }, - "labels": { - "aa": "OPG185: D29N" - } - }, - "children": [ - { - "name": "MPX/PT0090/2022", - "node_attrs": { - "div": 558, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-07-21" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MPX/PT0090/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP245340" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179155A", - "-179156T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179166T", - "-179167A", - "-179168T", - "-179170T" - ] - } - } - }, - { - "name": "Monkeypox/PT0579/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-09-10" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "Monkeypox/PT0579/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555650" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C41022T", - "A136513-", - "T136514-", - "C136515-" - ], - "OPG060": [ - "R54K" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG060: R54K; OPG153: D385-" - } - } - } - ] - }, - { - "name": "NODE_0000237", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C44333T", - "A150566-", - "T150567-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C" - ], - "OPG064": [ - "M522I" - ] - }, - "labels": { - "aa": "OPG064: M522I" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI085", - "node_attrs": { - "div": 559, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI085" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON853667" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G46956A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-" - ], - "OPG066": [ - "P158L" - ] - }, - "labels": { - "aa": "OPG066: P158L" - } - } - }, - { - "name": "MPX_luLfgA_9000208", - "node_attrs": { - "div": 558, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MPX_luLfgA_9000208" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415189" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/UZ_REGA_69", - "node_attrs": { - "div": 559, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-06-30" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_69" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035675" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G161488A", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_96", - "node_attrs": { - "div": 562, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-05-30" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_96" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035702" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C29315T", - "C60396T", - "G149807A", - "C161572T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG046": [ - "D139N" - ] - }, - "labels": { - "aa": "OPG046: D139N" - } - } - }, - { - "name": "NODE_0000238", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G93512T", - "-179209A", - "-179210T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG113": [ - "K594N" - ] - }, - "labels": { - "aa": "OPG113: K594N" - } - }, - "children": [ - { - "name": "SIC-AOUP-UNIPA_VL_9aug", - "node_attrs": { - "div": 562, - "author": { - "author": "Tramuto,F.", - "value": "Tramuto,F." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Palermo, Department of Health Promotion Sciences Maternal and Infant Care, Internal Medicine and Medical Specialties \"G. D'Alessandro\"" - }, - "date": { - "value": "2022-08-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "SIC-AOUP-UNIPA_VL_9aug" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP358276" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Italy" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C33103T", - "C114490T", - "C133295T", - "T179026-", - "A179027-", - "T179028-", - "G179029-", - "A179030-", - "A179031-", - "T179032-", - "A179033-", - "C179034-", - "G179035-", - "G179036-", - "A179037-", - "G179038-", - "T179039-", - "A179040-", - "C179041-", - "A179042-", - "A179043-" - ], - "OPG049": [ - "E17K" - ], - "OPG133": [ - "D403N" - ] - }, - "labels": { - "aa": "OPG049: E17K; OPG133: D403N" - } - } - }, - { - "name": "9000394", - "node_attrs": { - "div": 561, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "9000394" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536772" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C756T", - "G2898A", - "G3477A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C193733T", - "C194312T", - "G196454A" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000239", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A150566-", - "T150567-", - "C160426T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C" - ] - } - }, - "children": [ - { - "name": "NODE_0000240", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A10432-", - "T10433-", - "T10434-", - "A10435-", - "G10436-", - "G75332A", - "T124690C", - "C144211T", - "G185394A" - ], - "OPG095": [ - "R177K" - ], - "OPG210": [ - "E1347K" - ] - }, - "labels": { - "aa": "OPG095: R177K; OPG210: E1347K" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-119069/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2022-11-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-119069/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503754" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/USA/WA-UW-113327/2022", - "node_attrs": { - "div": 563, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2022-11-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-113327/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503755" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C135762T" - ] - } - } - } - ] - }, - { - "name": "NODE_0000241", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G111379A", - "G165326A", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG130": [ - "S175L" - ], - "OPG190": [ - "E69K" - ] - }, - "labels": { - "aa": "OPG130: S175L; OPG190: E69K" - } - }, - "children": [ - { - "name": "MPXV22/human/USA-OK-69", - "node_attrs": { - "div": 562, - "author": { - "author": "Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., O'Dell,J.X., Mannell,M., Wiley,M.R., Cross,S.T.", - "value": "Chapman,R.C., Bernhard,K., McCutchen,E.L., Fauver,J.R., O'Dell,J.X., Mannell,M., Wiley,M.R., Cross,S.T." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health" - }, - "date": { - "value": "2022-07-22" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MPXV22/human/USA-OK-69" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP351284" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "G22207A", - "C120671T", - "-196601A", - "-196602A", - "-196603A", - "A196616T" - ], - "OPG037": [ - "S76F" - ] - }, - "labels": { - "aa": "OPG037: S76F" - } - } - }, - { - "name": "MPXV_USA_2022_NY0025", - "node_attrs": { - "div": 560, - "author": { - "author": "Gigante,C., Ruiz,V., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Wang,J., Li,Y.", - "value": "Gigante,C., Ruiz,V., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Wang,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MPXV_USA_2022_NY0025" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ320464" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-" - ] - } - } - }, - { - "name": "NY-NYCPHL-000192", - "node_attrs": { - "div": 560, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-06-30" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "NY-NYCPHL-000192" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468827" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "NY-NYCPHL-000506", - "node_attrs": { - "div": 562, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-07-24" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "NY-NYCPHL-000506" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469105" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C5661T", - "C87013T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "G191549A" - ], - "NBT03_gp175": [ - "E166K" - ], - "OPG015": [ - "E166K" - ], - "OPG108": [ - "R16K" - ] - }, - "labels": { - "aa": "NBT03_gp175: E166K; OPG015: E166K; OPG108: R16K" - } - } - }, - { - "name": "NY-NYCPHL-000132", - "node_attrs": { - "div": 560, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-06-26" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "NY-NYCPHL-000132" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469143" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T150544-", - "A150545-", - "T150546-", - "G150547-", - "A150548-", - "A150549-", - "G150550-", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558A", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "NY-NYCPHL-000385", - "node_attrs": { - "div": 561, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-08-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "NY-NYCPHL-000385" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ504424" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G77478A" - ] - } - } - }, - { - "name": "NY-NYCPHL-000425", - "node_attrs": { - "div": 565, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-09-12" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "NY-NYCPHL-000425" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ504436" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G74391A", - "G98473A", - "C124495T", - "C132962T", - "C149264T" - ], - "OPG094": [ - "M204I" - ], - "OPG118": [ - "D10N" - ] - }, - "labels": { - "aa": "OPG094: M204I; OPG118: D10N" - } - } - }, - { - "name": "MPXV_USA_2022_OH0005", - "node_attrs": { - "div": 561, - "author": { - "author": "Gigante,C., Lee,B., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Salehi,E., Li,Y.", - "value": "Gigante,C., Lee,B., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Salehi,E., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.5" - }, - "strain_original": { - "value": "MPXV_USA_2022_OH0005" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ721933" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G48045A", - "A173306-", - "T173307-", - "A173308-", - "T173309-", - "A173310-", - "T173311-", - "A173312-", - "T173313-", - "A173314-", - "T173315-", - "A173316-", - "T173317-", - "G173318-", - "G173319-", - "G173320-", - "C173321-", - "A173322-", - "A173323-", - "A173324-", - "A173325-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-" - ] - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000242", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G74360A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A" - ], - "OPG094": [ - "R194H" - ] - }, - "labels": { - "aa": "OPG094: R194H", - "clade": "B.1.1" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI025", - "node_attrs": { - "div": 557, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI025" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON694329" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A192424-", - "T192425-", - "A192426-", - "A192427-", - "G192428-", - "T192429-", - "T192430-", - "A192431-", - "G192432-", - "T192433-", - "T192434-", - "A192435-", - "A192436-", - "G192437-", - "T192438-", - "C192439-", - "A192440-", - "T192441-", - "A192442-", - "A192443-", - "G192444-", - "T192445-", - "T192446-", - "A192447-", - "G192448-", - "T192449-", - "T192450-", - "A192451-", - "A192452-", - "G192453-", - "T192454-", - "C192455-", - "A192456-", - "T192457-", - "A192458-", - "A192459-", - "G192460-", - "T192461-", - "T192462-", - "A192463-", - "G192464-", - "T192465-", - "T192466-", - "A192467-", - "A192468-", - "G192469-", - "T192470-", - "C192471-" - ] - } - } - }, - { - "name": "hMpxV/Switzerland/ZH-UZH-IMV-3ba6450e/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Kufner,V., Ziltener,G., Zaheri,M., Schmutz,S., Audige,A., Bernasconi,O., Steiner,K., Huder,J., Shah,C., Capaul,R., Bloemberg,G., Boeni,J., Huber,M., Trkola,A.", - "value": "Kufner,V., Ziltener,G., Zaheri,M., Schmutz,S., Audige,A., Bernasconi,O., Steiner,K., Huder,J., Shah,C., Capaul,R., Bloemberg,G., Boeni,J., Huber,M., Trkola,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Zurich, Institute of Medical Virology" - }, - "date": { - "value": "2022-06-02" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "hMpxV/Switzerland/ZH-UZH-IMV-3ba6450e/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON792321" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Switzerland" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T9151-", - "A9152-", - "T9153-", - "T9154-", - "T9155-", - "T9156-", - "A9157-", - "T9158-", - "A9159-", - "A9160-", - "T9161-", - "A9162-", - "A9163-", - "T9164-", - "G9165-", - "T19299-", - "A19300-", - "C19301-", - "T19302-", - "A19303-", - "A19304-", - "G43539-", - "T43540-", - "C43541-", - "T49124-", - "G49125-", - "A49126-", - "T49127-", - "G49128-", - "C49129-", - "A49130-", - "A49131-", - "A49132-", - "A49133-", - "A49134-", - "A49135-", - "C49136-", - "G49137-", - "A49138-", - "C49139-", - "G49140-", - "A49141-", - "T79020-", - "A79021-", - "T79022-", - "T79023-", - "A79024-", - "T79025-", - "A79026-", - "T79027-", - "T79028-", - "T79029-", - "T79030-", - "T79031-", - "T79032-", - "A79033-", - "T79034-", - "C79035-", - "T79036-", - "A79037-", - "A79038-", - "A79039-", - "A79040-", - "A79041-", - "A79042-", - "C79043-", - "T79044-", - "A79045-", - "A79046-", - "A79047-", - "A79048-", - "A79049-", - "T79050-", - "A79051-", - "A79052-", - "A79053-", - "C79054-", - "A79055-", - "T79056-", - "T79057-", - "G79058-", - "A79059-", - "T152633-", - "C152634-", - "T152635-", - "A152636-", - "A152637-", - "T152638-", - "G152639-", - "A152640-", - "C175864-", - "A175865-", - "T175866-", - "C175867-", - "T175868-", - "A175869-", - "G175870-", - "C179127A", - "C179136T", - "T179138A", - "T179147-", - "T179156-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "C179190T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "A180392-", - "G180393-", - "T180394-", - "A180395-", - "T180396-", - "A180397-", - "G180398-" - ], - "OPG063": [ - "D50-" - ], - "OPG068": [ - "I308X", - "D309-", - "A310-", - "K311-", - "N312-", - "D313-", - "D314X", - "*568X" - ], - "OPG205": [ - "S70X", - "S71-", - "S72X", - "*788X" - ] - }, - "labels": { - "aa": "OPG063: D50-; OPG068: I308X, D309-, A310-, K311-, N312-, D313-, D314X, *568X; OPG205: S70X, S71-, S72X, *788X" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI182", - "node_attrs": { - "div": 557, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI182" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP018605" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-078327/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-078327/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP055801" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C133103T", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV-ROK-P1-2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Rhie,G.-E.", - "value": "Rhie,G.-E." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Korea Disease Control and Prevention Agency, Division of High-risk Pathogens" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV-ROK-P1-2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP204857" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "South Korea" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C786T", - "C71728T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G173429A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG091": [ - "A120V" - ] - }, - "labels": { - "aa": "OPG091: A120V" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI208", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI208" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP215245" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "G176536A", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG205": [ - "R294K" - ] - }, - "labels": { - "aa": "OPG205: R294K" - } - } - }, - { - "name": "MPXV_USA_2022_IL0042", - "node_attrs": { - "div": 557, - "author": { - "author": "Gigante,C.M., Ghinai,I., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Kerins,J., Li,Y.", - "value": "Gigante,C.M., Ghinai,I., Zhao,H., Batra,D., Hetrick,E.E., Howard,D.T., Kovar,L., Seabolt,M.H., Weigand,M.R., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Kerins,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV_USA_2022_IL0042" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP303785" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI324", - "node_attrs": { - "div": 557, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI324" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP355580" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "A188349-" - ] - } - } - }, - { - "name": "hMPXV-IHU00002", - "node_attrs": { - "div": 557, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "date": { - "value": "2022-07-01" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "hMPXV-IHU00002" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP382479" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179173A", - "-179174T", - "-179175T" - ] - } - } - }, - { - "name": "hMPXV-IHU00011", - "node_attrs": { - "div": 558, - "author": { - "author": "Colson,P.", - "value": "Colson,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "IHU - Mediterranee Infection, MEPHI" - }, - "date": { - "value": "2022-07-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "hMPXV-IHU00011" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP382488" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "-595T", - "C153387T", - "-179173A", - "-179174T", - "-179175T", - "A196599-", - "C196600-", - "-196602A" - ] - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-074978/2022", - "node_attrs": { - "div": 558, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-074978/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP434519" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C162401T", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "A185571-", - "G185572-", - "T185573-", - "G185574-", - "C185575-", - "A185576-", - "A185577-", - "T185578-", - "G185579-", - "A185580-", - "C185581-", - "G185582-", - "A185583-", - "T185584-", - "A185585-", - "A185586-", - "A185587-", - "A185588-", - "G185589-", - "T185590-", - "C185591-", - "C185592-", - "T185593-", - "A185594-", - "C185595-", - "C185596-", - "A185597-", - "T185598-", - "G185599-", - "T185600-", - "A185601-", - "C185602-", - "A185603-", - "G185604-", - "T185605-", - "G185606-", - "A185607-", - "G185608-", - "A185609-", - "A185610-", - "A185611-", - "T185612-", - "A185613-", - "A185614-", - "A185615-", - "A185616-", - "A185617-", - "T185618-", - "A185619-", - "T185620-", - "A185621-", - "G185622-", - "A185623-", - "C185624-", - "T185625-", - "T185626-", - "T185627-", - "G185628-", - "G185629-", - "A185630-", - "T185631-", - "A185632-", - "T185633-", - "A185634-", - "A185635-", - "C185636-", - "T185637-", - "A185638-", - "T185639-", - "G185640-", - "G185641-", - "A185642-", - "G185643-", - "A185644-", - "T185645-", - "A185646-", - "T185647-", - "T185648-", - "A185649-", - "T185650-", - "T185651-", - "T185652-", - "C185653-", - "T185654-", - "A185655-", - "A185656-", - "T185657-", - "A185658-", - "T185659-", - "G185660-", - "G185661-", - "T185662-", - "T185663-", - "T185664-", - "A185665-", - "T185666-", - "C185667-", - "T185668-", - "A185669-", - "C185670-", - "A185671-", - "A185672-", - "T185673-", - "C185674-", - "T185675-", - "A185676-", - "C185677-", - "T185678-", - "A185679-", - "G185680-", - "T185681-", - "C185682-", - "A185683-", - "G185684-", - "G185685-", - "A185686-", - "T185687-", - "T185688-", - "A185689-", - "T185690-", - "G185691-", - "G185692-", - "A185693-", - "G185694-", - "A185695-", - "T185696-", - "G185697-", - "G185698-", - "T185699-", - "A185700-", - "C185701-", - "C185702-", - "A185703-", - "A185704-", - "A185705-", - "T185706-", - "A185707-", - "T185708-", - "A185709-", - "C185710-", - "A185711-", - "T185712-", - "T185713-", - "T185714-", - "A185715-", - "A185716-", - "A185717-", - "T185718-", - "C185719-", - "C185720-", - "G185721-", - "T185722-", - "A185723-", - "A185724-", - "C185725-", - "T185726-", - "A185727-", - "G185728-", - "A185729-", - "T185730-", - "C185731-", - "A185732-", - "G185733-", - "A185734-", - "T185735-", - "C185736-", - "A185737-", - "T185738-", - "G185739-", - "A185740-", - "G185741-", - "T185742-", - "G185743-", - "T185744-", - "G185745-", - "A185746-", - "A185747-", - "T185748-", - "C185749-", - "T185750-", - "A185751-", - "G185752-", - "C185753-", - "T185754-", - "T185755-", - "A185756-", - "G185757-", - "A185758-", - "T185759-", - "C185760-", - "T185761-", - "A185762-", - "A185763-", - "C185764-", - "G185765-", - "T185766-", - "C185767-", - "T185768-", - "A185769-", - "A185770-", - "G185771-", - "G185772-", - "A185773-", - "A185774-", - "G185775-", - "T185776-", - "A185777-", - "A185778-", - "C185779-", - "T185780-", - "G185781-", - "T185782-", - "G185783-", - "A185784-", - "C185785-", - "A185786-", - "T185787-", - "G185788-", - "T185789-", - "C185790-", - "C185791-", - "T185792-", - "G185793-", - "C185794-", - "G185795-", - "T185796-", - "T185797-", - "T185798-", - "A185799-", - "G185800-", - "T185801-", - "A185802-", - "T185803-", - "A185804-", - "C185805-", - "C185806-", - "A185807-", - "A185808-", - "G185809-", - "A185810-", - "A185811-", - "A185812-", - "T185813-", - "A185814-", - "T185815-", - "A185816-", - "T185817-", - "C185818-", - "A185819-", - "A185820-", - "C185821-", - "A185822-", - "T185823-", - "A185824-", - "T185825-", - "G185826-", - "A185827-", - "A185828-", - "G185829-", - "G185830-", - "T185831-", - "C185832-", - "T185833-", - "A185834-", - "T185835-", - "G185836-", - "C185837-", - "T185838-", - "T185839-", - "T185840-", - "A185841-", - "G185842-", - "T185843-", - "G185844-", - "T185845-", - "T185846-", - "A185847-", - "C185848-", - "T185849-", - "A185850-", - "C185851-", - "A185852-", - "T185853-", - "C185854-", - "T185855-", - "A185856-", - "A185857-", - "A185858-", - "G185859-", - "A185860-", - "T185861-", - "C185862-", - "A185863-", - "T185864-", - "T185865-", - "G185866-", - "T185867-", - "G185868-", - "C185869-", - "T185870-", - "A185871-", - "C185872-", - "A185873-", - "G185874-", - "G185875-", - "T185876-", - "A185877-", - "T185878-", - "T185879-", - "G185880-", - "G185881-", - "T185882-", - "T185883-", - "G185884-", - "G185885-", - "T185886-", - "T185887-", - "A185888-", - "A185889-", - "A185890-", - "A185891-", - "T185892-", - "C185893-", - "T185894-", - "A185895-", - "G185896-", - "T185897-", - "G185898-", - "G185899-", - "T185900-", - "T185901-", - "A185902-", - "T185903-", - "G185904-", - "G185905-", - "G185906-", - "A185907-", - "A185908-", - "G185909-", - "G185910-", - "A185911-", - "A185912-", - "G185913-", - "A185914-", - "T185915-", - "G185916-", - "C185917-", - "T185918-", - "G185919-", - "A185920-", - "T185921-", - "A185922-", - "A185923-", - "A185924-", - "C185925-", - "C185926-", - "A185927-", - "C185928-", - "G185929-", - "T185930-", - "G185931-", - "C185932-", - "T185933-", - "T185934-", - "G185935-", - "T185936-", - "T185937-", - "T185938-", - "T185939-", - "C185940-", - "A185941-", - "T185942-", - "C185943-", - "A185944-", - "T185945-", - "T185946-", - "G185947-", - "G185948-", - "A185949-", - "A185950-", - "T185951-", - "T185952-", - "A185953-", - "T185954-", - "T185955-", - "A185956-", - "C185957-", - "A185958-", - "C185959-", - "A185960-", - "C185961-", - "T185962-", - "G185963-", - "T185964-", - "C185965-", - "G185966-", - "T185967-", - "T185968-", - "G185969-", - "G185970-", - "A185971-", - "T185972-", - "T185973-", - "A185974-", - "T185975-", - "T185976-", - "A185977-", - "C185978-", - "T185979-", - "G185980-", - "T185981-", - "T185982-", - "C185983-", - "A185984-", - "T185985-", - "A185986-", - "C185987-", - "G185988-", - "A185989-", - "A185990-", - "G185991-", - "A185992-", - "T185993-", - "A185994-", - "T185995-", - "T185996-", - "T185997-", - "G185998-", - "G185999-", - "A186000-", - "G186001-", - "A186002-", - "A186003-", - "G186004-", - "C186005-", - "A186006-", - "C186007-", - "C186008-", - "T186009-", - "G186010-", - "G186011-", - "C186012-", - "C186013-", - "T186014-", - "G186015-", - "A186016-", - "C186017-", - "T186018-", - "A186019-", - "T186020-", - "G186021-", - "A186022-", - "T186023-", - "C186024-", - "C186025-", - "A186026-", - "T186027-", - "G186028-", - "T186029-", - "A186030-", - "A186031-", - "G186032-", - "T186033-", - "C186034-", - "A186035-", - "T186036-", - "A186037-", - "T186038-", - "A186039-", - "T186040-", - "C186041-", - "C186042-", - "A186043-", - "T186044-", - "A186045-", - "T186046-", - "A186047-", - "G186048-", - "A186049-", - "G186050-", - "T186051-", - "A186052-", - "T186053-", - "A186054-", - "G186055-", - "A186056-", - "G186057-", - "A186058-", - "T186059-", - "A186060-", - "C186061-", - "A186062-", - "T186063-", - "G186064-", - "G186065-", - "A186066-", - "T186067-", - "A186068-", - "G186069-", - "A186070-", - "A186071-", - "T186072-", - "C186073-", - "T186074-", - "A186075-", - "A186076-", - "T186077-", - "G186078-", - "T186079-", - "G186080-", - "T186081-", - "T186082-", - "A186083-", - "C186084-", - "A186085-", - "G186086-", - "C186087-", - "A186088-", - "A186089-", - "C186090-", - "C186091-", - "T186092-", - "C186093-", - "C186094-", - "T186095-", - "T186096-", - "A186097-", - "C186098-", - "A186099-", - "C186100-", - "A186101-", - "T186102-", - "T186103-", - "C186104-", - "G186105-", - "A186106-", - "A186107-", - "T186108-", - "T186109-", - "C186110-", - "A186111-", - "T186112-", - "T186113-", - "C186114-", - "A186115-", - "T186116-", - "G186117-", - "A186118-", - "C186119-", - "A186120-", - "A186121-", - "T186122-", - "T186123-", - "C186124-", - "T186125-", - "A186126-", - "A186127-", - "C186128-", - "G186129-", - "A186130-", - "A186131-", - "T186132-", - "A186133-", - "T186134-", - "G186135-", - "T186136-", - "G186137-", - "G186138-", - "A186139-", - "T186140-", - "A186141-", - "A186142-", - "A186143-", - "G186144-", - "A186145-", - "A186146-", - "A186147-", - "T186148-", - "T186149-", - "A186150-", - "G186151-", - "T186152-", - "A186153-", - "A186154-", - "C186155-", - "A186156-", - "A186157-", - "A186158-", - "T186159-", - "T186160-", - "A186161-", - "A186162-", - "A186163-", - "T186164-", - "G186165-", - "A186166-", - "T186167-", - "C186168-", - "T186169-", - "G186170-", - "T186171-", - "A186172-", - "C186173-", - "A186174-", - "A186175-", - "T186176-", - "G186177-", - "A186178-", - "A186179-", - "T186180-", - "A186181-", - "C186182-", - "A186183-", - "A186184-", - "G186185-", - "A186186-", - "A186187-", - "G186188-", - "A186189-", - "T186190-", - "T186191-", - "A186192-", - "T186193-", - "G186194-", - "G186195-", - "A186196-", - "A186197-", - "T186198-", - "A186199-", - "T186200-", - "A186201-", - "G186202-", - "C186203-", - "G186204-", - "A186205-", - "C186206-", - "G186207-", - "G186208-", - "A186209-", - "T186210-", - "C186211-", - "A186212-", - "T186213-", - "T186214-", - "G186215-", - "C186216-", - "C186217-", - "G186218-", - "G186219-", - "C186220-", - "G186221-", - "T186222-", - "C186223-", - "T186224-", - "A186225-", - "T186226-", - "A186227-", - "A186228-", - "A186229-", - "C186230-", - "A186231-", - "G186232-", - "A186233-", - "T186234-", - "T186235-", - "A186236-", - "G186237-", - "C186238-", - "A186239-", - "A186240-", - "A186241-", - "G186242-", - "G186243-", - "C186244-", - "A186245-", - "T186246-", - "T186247-", - "G186248-", - "A186249-", - "C186250-", - "T186251-", - "T186252-", - "C186253-", - "A186254-", - "G186255-", - "A186256-", - "G186257-", - "G186258-", - "G186259-", - "T186260-", - "A186261-", - "G186262-", - "A186263-", - "G186264-", - "A186265-", - "A186266-", - "A186267-", - "T186268-", - "A186269-", - "G186270-", - "C186271-", - "A186272-", - "A186273-", - "G186274-", - "T186275-", - "G186276-", - "T186277-", - "T186278-", - "A186279-", - "A186280-", - "T186281-", - "A186282-", - "T186283-", - "A186284-", - "G186285-", - "A186286-", - "T186287-", - "G186288-", - "G186289-", - "T186290-", - "A186291-", - "A186292-", - "T186293-", - "C186294-", - "T186295-", - "G186296-", - "T186297-", - "T186298-", - "A186299-", - "G186300-", - "A186301-", - "T186302-", - "A186303-", - "T186304-", - "C186305-", - "G186306-", - "C186307-", - "A186308-", - "T186309-", - "A186310-", - "T186311-", - "C186312-", - "A186313-", - "A186314-", - "G186315-", - "C186316-", - "A186317-", - "G186318-", - "A186319-", - "T186320-", - "A186321-", - "A186322-", - "G186323-", - "G186324-", - "A186325-", - "A186326-", - "A186327-", - "A186328-", - "G186329-", - "A186330-", - "T186331-", - "G186332-", - "G186333-", - "C186334-", - "C186335-", - "G186336-", - "A186337-", - "C186338-", - "A186339-", - "T186340-", - "A186341-", - "C186342-", - "A186343-", - "G186344-", - "A186345-", - "C186346-", - "A186347-", - "A186348-", - "G186349-", - "A186350-", - "A186351-", - "T186352-", - "A186353-", - "A186354-", - "A186355-", - "T186356-", - "G186357-", - "A186358-", - "T186359-", - "A186360-", - "T186361-", - "T186362-", - "A186363-", - "T186364-", - "T186365-", - "A186366-", - "G186367-", - "A186368-", - "G186369-", - "A186370-", - "T186371-", - "T186372-", - "T186373-", - "G186374-", - "T186375-", - "T186376-", - "T186377-", - "A186378-", - "T186379-", - "A186380-", - "C186381-", - "A186382-", - "C186383-", - "A186384-", - "C186385-", - "T186386-", - "C186387-", - "T186388-", - "A186389-", - "T186390-", - "C186391-", - "A186392-", - "G186393-", - "A186394-", - "C186395-", - "A186396-", - "A186397-", - "A186398-", - "G186399-", - "A186400-", - "T186401-", - "A186402-", - "T186403-", - "A186404-", - "A186405-", - "A186406-", - "A186407-", - "G186408-", - "A186409-", - "C186410-", - "A186411-", - "T186412-", - "T186413-", - "A186414-", - "T186415-", - "A186416-", - "G186417-", - "A186418-", - "A186419-", - "T186420-", - "C186421-", - "C186422-", - "G186423-", - "A186424-", - "A186425-", - "G186426-", - "A186427-", - "A186428-", - "G186429-", - "G186430-", - "T186431-", - "A186432-", - "A186433-", - "G186434-", - "A186435-", - "G186436-", - "A186437-", - "T186438-", - "G186439-", - "T186440-", - "T186441-", - "G186442-", - "T186443-", - "A186444-", - "T186445-", - "A186446-", - "A186447-", - "T186448-", - "A186449-", - "G186450-", - "A186451-", - "T186452-", - "G186453-", - "T186454-", - "T186455-", - "A186456-", - "A186457-", - "G186458-", - "A186459-", - "A186460-", - "C186461-", - "A186462-", - "A186463-", - "T186464-", - "C186465-", - "T186466-", - "T186467-", - "G186468-", - "T186469-", - "T186470-", - "A186471-", - "A186472-", - "A186473-", - "A186474-", - "A186475-", - "G186476-", - "T186477-", - "A186478-", - "C186479-", - "T186480-", - "A186481-", - "T186482-", - "T186483-", - "C186484-", - "T186485-", - "A186486-", - "T186487-", - "T186488-", - "G186489-", - "A186490-", - "T186491-", - "A186492-", - "A186493-", - "T186494-", - "T186495-", - "A186496-", - "T186497-", - "C186498-", - "T186499-", - "A186500-", - "T186501-", - "G186502-", - "T186503-", - "G186504-", - "A186505-", - "T186506-", - "A186507-", - "C186508-", - "T186509-", - "T186510-", - "T186511-", - "A186512-", - "G186513-", - "A186514-", - "T186515-", - "G186516-", - "A186517-", - "T186518-", - "T186519-", - "A186520-", - "T186521-", - "A186522-", - "T186523-", - "A186524-", - "T186525-", - "A186526-", - "C186527-", - "A186528-", - "C186529-", - "C186530-", - "T186531-", - "C186532-", - "T186533-", - "G186534-", - "T186535-", - "A186536-", - "G186537-", - "A186538-", - "A186539-", - "T186540-", - "A186541-", - "T186542-", - "A186543-", - "A186544-", - "C186545-", - "A186546-", - "A186547-", - "A186548-", - "T186549-", - "C186550-", - "C186551-", - "T186552-", - "A186553-", - "T186554-", - "G186555-", - "T186556-", - "G186557-", - "T186558-", - "T186559-", - "A186560-", - "G186561-", - "T186562-", - "A186563-", - "A186564-", - "A186565-", - "C186566-", - "G186567-", - "A186568-", - "T186569-", - "A186570-", - "C186571-", - "T186572-", - "T186573-", - "A186574-", - "T186575-", - "A186576-", - "T186577-", - "A186578-", - "A186579-", - "G186580-", - "C186581-", - "T186582-", - "A186583-", - "T186584-", - "G186585-", - "A186586-", - "C186587-", - "T186588-", - "A186589-", - "T186590-", - "C186591-", - "T186592-", - "T186593-", - "G186594-", - "A186595-", - "A186596-", - "T186597-", - "C186598-", - "A186599-", - "T186600-", - "C186601-", - "A186602-", - "G186603-", - "G186604-", - "T186605-", - "G186606-", - "T186607-", - "A186608-", - "G186609-", - "T186610-", - "T186611-", - "G186612-", - "T186613-", - "T186614-", - "C186615-", - "T186616-", - "A186617-", - "T186618-", - "C186619-", - "A186620-", - "T186621-", - "G186622-", - "T186623-", - "T186624-", - "A186625-", - "T186626-", - "G186627-", - "A186628-", - "A186629-", - "A186630-", - "T186631-", - "G186632-", - "A186633-", - "C186634-", - "T186635-", - "A186636-", - "T186637-", - "A186638-", - "A186639-", - "T186640-", - "C186641-", - "T186642-", - "C186643-", - "C186644-", - "T186645-", - "T186646-", - "G186647-", - "G186648-", - "A186649-", - "T186650-", - "A186651-", - "C186652-", - "A186653-", - "A186654-", - "A186655-", - "A186656-", - "G186657-", - "A186658-", - "C186659-", - "G186660-", - "C186661-", - "C186662-", - "A186663-", - "A186664-", - "A186665-", - "G186666-", - "A186667-", - "T186668-", - "G186669-", - "C186670-", - "T186671-", - "A186672-", - "T186673-", - "A186674-", - "G186675-", - "A186676-", - "A186677-", - "G186678-", - "A186679-", - "T186680-", - "G186681-", - "T186682-", - "G186683-", - "A186684-", - "T186685-", - "A186686-", - "G186687-", - "T186688-", - "A186689-", - "G186690-", - "C186691-", - "A186692-", - "A186693-", - "G186694-", - "T186695-", - "G186696-", - "C186697-", - "G186698-", - "G186699-", - "T186700-", - "A186701-", - "G186702-", - "C186703-", - "C186704-", - "G186705-", - "A186706-", - "A186707-", - "G186708-", - "C186709-", - "A186710-", - "T186711-", - "T186712-", - "G186713-", - "A186714-", - "A186715-", - "T186716-", - "G186717-", - "A186718-", - "C186719-", - "A186720-", - "T186721-", - "G186722-", - "T186723-", - "T186724-", - "T186725-", - "A186726-", - "A186727-", - "G186728-", - "G186729-", - "A186730-", - "A186731-", - "T186732-", - "T186733-", - "T186734-", - "G186735-", - "A186736-", - "T186737-", - "A186738-", - "A186739-", - "A186740-", - "A186741-", - "A186742-", - "C186743-", - "G186744-", - "T186745-", - "A186746-", - "A186747-", - "G186748-", - "T186749-", - "G186750-", - "C186751-", - "T186752-", - "A186753-", - "T186754-", - "T186755-", - "A186756-", - "T186757-", - "A186758-", - "A186759-", - "T186760-", - "A186761-", - "A186762-", - "A186763-", - "A186764-", - "G186765-", - "A186766-", - "A186767-", - "G186768-", - "A186769-", - "A186770-", - "G186771-", - "A186772-", - "T186773-", - "A186774-", - "A186775-", - "T186776-", - "T186777-", - "A186778-", - "T186779-", - "C186780-", - "T186781-", - "A186782-", - "A186783-", - "A186784-", - "C186785-", - "A186786-", - "G186787-", - "T186788-", - "T186789-", - "C186790-", - "G186791-", - "C186792-", - "C186793-", - "C186794-", - "G186795-", - "A186796-", - "T186797-", - "A186798-", - "T186799-", - "C186800-", - "T186801-", - "A186802-", - "C186803-", - "C186804-", - "A186805-", - "T186806-", - "A186807-", - "T186808-", - "A186809-", - "A186810-", - "T186811-", - "A186812-", - "T186813-", - "A186814-", - "T186815-", - "A186816-", - "T186817-", - "C186818-", - "A186819-", - "T186820-", - "A186821-", - "G186822-", - "G186823-", - "T186824-", - "G186825-", - "G186826-", - "C186827-", - "A186828-", - "C186829-", - "T186830-", - "A186831-", - "T186832-", - "T186833-", - "C186834-", - "T186835-", - "G186836-", - "C186837-", - "T186838-", - "A186839-", - "C186840-", - "T186841-", - "G186842-", - "T186843-", - "T186844-", - "A186845-", - "G186846-", - "T186847-", - "C186848-", - "A186849-", - "T186850-", - "T186851-", - "A186852-", - "T186853-", - "T186854-", - "T186855-", - "T186856-", - "A186857-", - "A186858-", - "T186859-", - "A186860-", - "T186861-", - "T186862-", - "G186863-", - "G186864-", - "C186865-", - "A186866-", - "A186867-", - "T186868-", - "T186869-", - "T186870-", - "A186871-", - "T186872-", - "A186873-", - "T186874-", - "A186875-", - "G186876-", - "C186877-", - "G186878-", - "C186879-", - "G186880-", - "C186881-", - "A186882-", - "A186883-", - "T186884-", - "A186885-", - "A186886-", - "A186887-", - "T186888-", - "A186889-", - "C186890-", - "A186891-", - "G186892-", - "A186893-", - "A186894-", - "C186895-", - "C186896-", - "A186897-", - "G186898-", - "G186899-", - "A186900-", - "A186901-", - "A186902-", - "T186903-", - "A186904-", - "T186905-", - "G186906-", - "A186907-", - "A186908-", - "A186909-", - "T186910-", - "A186911-", - "A186912-", - "T186913-", - "G186914-", - "A186915-", - "A186916-", - "A186917-", - "T186918-", - "A186919-", - "T186920-", - "G186921-", - "A186922-", - "C186923-", - "A186924-", - "A186925-", - "T186926-", - "A186927-", - "T186928-", - "G186929-", - "A186930-", - "G186931-", - "C186932-", - "A186933-", - "T186934-", - "T186935-", - "A186936-", - "A186937-", - "A186938-", - "T186939-", - "C186940-", - "T186941-", - "G186942-", - "A186943-", - "G186944-", - "C186945-", - "A186946-", - "T186947-", - "C186948-", - "A186949-", - "T186950-", - "G186951-", - "A186952-", - "T186953-", - "A186954-", - "G186955-", - "T186956-", - "C186957-", - "T186958-", - "T186959-", - "G186960-", - "A186961-", - "A186962-", - "A186963-", - "C186964-", - "A186965-", - "G186966-", - "T186967-", - "G186968-", - "T186969-", - "C186970-", - "T186971-", - "A186972-", - "T186973-", - "G186974-", - "G186975-", - "A186976-", - "A186977-", - "A186978-", - "T186979-", - "T186980-", - "A186981-", - "T186982-", - "T186983-", - "G186984-", - "A186985-", - "T186986-", - "A186987-", - "A186988-", - "T186989-", - "C186990-", - "G186991-", - "G186992-", - "T186993-", - "A186994-", - "C186995-", - "T186996-", - "A186997-", - "A186998-", - "T186999-", - "A187000-", - "A187001-", - "A187002-", - "A187003-", - "T187004-", - "A187005-", - "G187006-", - "T187007-", - "T187008-", - "T187009-", - "A187010-", - "A187011-", - "C187012-", - "T187013-", - "C187014-", - "T187015-", - "T187016-", - "T187017-", - "T187018-", - "A187019-", - "G187020-", - "A187021-", - "A187022-", - "C187023-", - "C187024-", - "A187025-", - "G187026-", - "T187027-", - "T187028-", - "T187029-", - "G187030-", - "G187031-", - "T187032-", - "A187033-", - "C187034-", - "T187035-", - "G187036-", - "T187037-", - "A187038-", - "A187039-", - "T187040-", - "T187041-", - "T187042-", - "C187043-", - "A187044-", - "G187045-", - "T187046-", - "T187047-", - "C187048-", - "A187049-", - "T187050-", - "T187051-", - "A187052-", - "C187053-", - "T187054-", - "C187055-", - "G187056-", - "T187057-", - "T187058-", - "G187059-", - "A187060-", - "G187061-", - "A187062-", - "A187063-", - "T187064-", - "A187065-", - "T187066-", - "T187067-", - "G187068-", - "A187069-", - "T187070-", - "G187071-", - "A187072-", - "T187073-", - "T187074-", - "T187075-", - "T187076-", - "T187077-", - "T187078-", - "T187079-", - "T187080-", - "A187081-", - "A187082-", - "A187083-", - "T187084-", - "G187085-", - "A187086-", - "G187087-", - "T187088-", - "A187089-", - "T187090-", - "C187091-", - "G187092-", - "G187093-", - "T187094-", - "A187095-", - "G187096-", - "T187097-", - "T187098-", - "A187099-", - "C187100-", - "A187101-", - "T187102-", - "A187103-", - "T187104-", - "T187105-", - "A187106-", - "C187107-", - "C187108-", - "A187109-", - "T187110-", - "A187111-", - "T187112-", - "C187113-", - "A187114-", - "T187115-", - "C187116-", - "C187117-", - "A187118-", - "T187119-", - "T187120-", - "A187121-", - "T187122-", - "A187123-", - "T187124-", - "A187125-", - "A187126-", - "T187127-", - "C187128-", - "G187129-", - "A187130-", - "T187131-", - "G187132-", - "A187133-", - "T187134-", - "G187135-", - "C187136-", - "A187137-", - "T187138-", - "G187139-", - "T187140-", - "A187141-", - "T187142-", - "T187143-", - "A187144-", - "G187145-", - "A187146-", - "A187147-", - "T187148-", - "A187149-", - "C187150-", - "T187151-", - "T187152-", - "T187153-", - "C187154-", - "C187155-", - "G187156-", - "A187157-", - "A187158-", - "T187159-", - "A187160-", - "A187161-", - "G187162-", - "T187163-", - "C187164-", - "T187165-", - "T187166-", - "C187167-", - "T187168-", - "A187169-", - "A187170-", - "A187171-", - "T187172-", - "A187173-", - "T187174-", - "T187175-", - "G187176-", - "T187177-", - "A187178-", - "T187179-", - "T187180-", - "A187181-", - "A187182-", - "T187183-", - "T187184-", - "A187185-", - "T187186-", - "G187187-", - "A187188-", - "A187189-", - "A187190-", - "A187191-", - "A187192-", - "C187193-", - "T187194-", - "A187195-", - "T187196-", - "G187197-", - "C187198-", - "T187199-", - "A187200-", - "T187201-", - "G187202-", - "T187203-", - "G187204-", - "A187205-", - "G187206-", - "T187207-", - "A187208-", - "T187209-", - "G187210-", - "A187211-", - "T187212-", - "T187213-", - "C187214-", - "A187215-", - "A187216-", - "A187217-", - "G187218-", - "A187219-", - "T187220-", - "G187221-", - "T187222-", - "T187223-", - "T187224-", - "A187225-", - "A187226-", - "T187227-", - "G187228-", - "A187229-", - "T187230-", - "A187231-", - "C187232-", - "G187233-", - "A187234-", - "T187235-", - "A187236-", - "C187237-", - "T187238-", - "A187239-", - "G187240-", - "A187241-", - "T187242-", - "T187243-", - "T187244-", - "T187245-", - "A187246-", - "T187247-", - "C187248-", - "T187249-", - "C187250-", - "T187251-", - "A187252-", - "G187253-", - "C187254-", - "G187255-", - "A187256-", - "G187257-", - "A187258-", - "T187259-", - "T187260-", - "G187261-", - "T187262-", - "T187263-", - "T187264-", - "A187265-", - "G187266-", - "A187267-", - "A187268-", - "T187269-", - "C187270-", - "A187271-", - "T187272-", - "T187273-", - "T187274-", - "A187275-", - "T187276-", - "C187277-", - "A187278-", - "T187279-", - "A187280-", - "A187281-", - "C187282-", - "T187283-", - "A187284-", - "T187285-", - "G187286-", - "T187287-", - "T187288-", - "T187289-", - "A187290-", - "A187291-", - "T187292-", - "A187293-", - "A187294-", - "A187295-", - "T187296-", - "T187297-", - "C187298-", - "A187299-", - "T187300-", - "C187301-", - "A187302-", - "A187303-", - "C187304-", - "G187305-", - "A187306-", - "A187307-", - "T187308-", - "A187309-", - "T187310-", - "C187311-", - "G187312-", - "A187313-", - "T187314-", - "A187315-", - "A187316-", - "A187317-", - "G187318-", - "A187319-", - "C187320-", - "C187321-", - "T187322-", - "C187323-", - "T187324-", - "T187325-", - "G187326-", - "T187327-", - "A187328-", - "A187329-", - "T187330-", - "T187331-", - "C187332-", - "G187333-", - "A187334-", - "G187335-", - "T187336-", - "A187337-", - "T187338-", - "A187339-", - "G187340-", - "G187341-", - "A187342-", - "A187343-", - "G187344-", - "T187345-", - "A187346-", - "G187347-", - "T187348-", - "A187349-", - "T187350-", - "T187351-", - "A187352-", - "C187353-", - "C187354-", - "A187355-", - "T187356-", - "A187357-", - "T187358-", - "C187359-", - "A187360-", - "A187361-", - "C187362-", - "T187363-", - "T187364-", - "C187365-", - "C187366-", - "G187367-", - "A187368-", - "G187369-", - "T187370-", - "T187371-", - "A187372-", - "A187373-", - "C187374-", - "A187375-", - "A187376-", - "T187377-", - "T187378-", - "A187379-", - "C187380-", - "T187381-", - "C187382-", - "T187383-", - "A187384-", - "A187385-", - "A187386-", - "A187387-", - "C187388-", - "A187389-", - "T187390-", - "G187391-", - "A187392-", - "G187393-", - "G187394-", - "A187395-", - "T187396-", - "T187397-", - "G187398-", - "T187399-", - "A187400-", - "C187401-", - "T187402-", - "C187403-", - "C187404-", - "T187405-", - "G187406-", - "T187407-", - "C187408-", - "T187409-", - "T187410-", - "T187411-", - "A187412-", - "T187413-", - "T187414-", - "G187415-", - "G187416-", - "A187417-", - "G187418-", - "A187419-", - "T187420-", - "C187421-", - "A187422-", - "C187423-", - "T187424-", - "A187425-", - "T187426-", - "T187427-", - "T187428-", - "A187429-", - "G187430-", - "T187431-", - "C187432-", - "G187433-", - "T187434-", - "T187435-", - "G187436-", - "A187437-", - "T187438-", - "A187439-", - "A187440-", - "A187441-", - "C187442-", - "T187443-", - "A187444-", - "G187445-", - "T187446-", - "A187447-", - "A187448-", - "C187449-", - "C187450-", - "T187451-", - "C187452-", - "A187453-", - "G187454-", - "G187455-", - "T187456-", - "T187457-", - "T187458-", - "C187459-", - "T187460-", - "T187461-", - "T187462-", - "A187463-", - "C187464-", - "A187465-", - "A187466-", - "A187467-", - "C187468-", - "G187469-", - "A187470-", - "T187471-", - "A187472-", - "A187473-", - "A187474-", - "G187475-", - "T187476-", - "A187477-", - "C187478-", - "A187479-", - "A187480-", - "C187481-", - "A187482-", - "T187483-", - "C187484-", - "A187485-", - "A187486-", - "G187487-", - "A187488-", - "C187489-", - "C187490-", - "T187491-", - "C187492-", - "A187493-", - "C187494-", - "A187495-", - "A187496-", - "C187497-", - "A187498-", - "C187499-", - "A187500-", - "G187501-", - "T187502-", - "G187503-", - "C187504-", - "A187505-", - "A187506-", - "G187507-", - "A187508-", - "T187509-", - "T187510-", - "A187511-", - "A187512-", - "T187513-", - "C187514-", - "T187515-", - "A187516-", - "G187517-", - "A187518-", - "A187519-", - "A187520-", - "T187521-", - "C187522-", - "A187523-", - "A187524-", - "A187525-", - "T187526-", - "G187527-", - "T187528-", - "A187529-", - "A187530-", - "T187531-", - "T187532-", - "C187533-", - "T187534-", - "G187535-", - "G187536-", - "A187537-", - "G187538-", - "G187539-", - "A187540-", - "G187541-", - "A187542-", - "A187543-", - "T187544-", - "C187545-", - "T187546-", - "A187547-", - "G187548-", - "A187549-", - "C187550-", - "A187551-", - "A187552-", - "C187553-", - "T187554-", - "A187555-", - "A187556-", - "C187557-", - "A187558-", - "C187559-", - "C187560-", - "C187561-", - "A187562-", - "C187563-", - "G187564-", - "G187565-", - "C187566-", - "G187567-", - "A187568-", - "A187569-", - "G187570-", - "T187571-", - "A187572-", - "T187573-", - "A187574-", - "C187575-", - "T187576-", - "T187577-", - "T187578-", - "A187579-", - "T187580-", - "G187581-", - "C187582-", - "C187583-", - "T187584-", - "C187585-", - "A187586-", - "T187587-", - "T187588-", - "C187589-", - "A187590-", - "G187591-", - "A187592-", - "A187593-", - "A187594-", - "C187595-", - "G187596-", - "G187597-", - "T187598-", - "A187599-", - "A187600-", - "C187601-", - "T187602-", - "G187603-", - "T187604-", - "A187605-", - "G187606-", - "T187607-", - "A187608-", - "G187609-", - "G187610-", - "A187611-", - "G187612-", - "A187613-", - "C187614-", - "T187615-", - "G187616-", - "T187617-", - "C187618-", - "T187619-", - "C187620-", - "T187621-", - "C187622-", - "T187623-", - "A187624-", - "A187625-", - "T187626-", - "C187627-", - "T187628-", - "C187629-", - "G187630-", - "A187631-", - "T187632-", - "G187633-", - "T187634-", - "A187635-", - "T187636-", - "A187637-", - "T187638-", - "A187639-", - "T187640-", - "A187641-", - "A187642-", - "T187643-", - "A187644-", - "T187645-", - "A187646-", - "T187647-", - "A187648-", - "C187649-", - "C187650-", - "A187651-", - "A187652-", - "T187653-", - "A187654-", - "C187655-", - "G187656-", - "G187657-", - "A187658-", - "C187659-", - "G187660-", - "C187661-", - "G187662-", - "A187663-", - "T187664-", - "A187665-", - "T187666-", - "A187667-", - "T187668-", - "T187669-", - "C187670-", - "C187671-", - "G187672-", - "A187673-", - "C187674-", - "A187675-", - "T187676-", - "G187677-", - "A187678-", - "A187679-", - "T187680-", - "G187681-", - "G187682-", - "C187683-", - "G187684-", - "T187685-", - "C187686-", - "G187687-", - "C187688-", - "T187689-", - "T187690-", - "A187691-", - "T187692-", - "C187693-", - "A187694-", - "T187695-", - "A187696-", - "T187697-", - "G187698-", - "T187699-", - "T187700-", - "A187701-", - "T187702-", - "A187703-", - "T187704-", - "C187705-", - "C187706-", - "T187707-", - "A187708-", - "A187709-", - "A187710-", - "T187711-", - "G187712-", - "T187713-", - "T187714-", - "G187715-", - "A187716-", - "T187717-", - "C187718-", - "A187719-", - "T187720-", - "A187721-", - "T187722-", - "T187723-", - "C187724-", - "C187725-", - "A187726-", - "C187727-", - "A187728-", - "A187729-", - "A187730-", - "T187731-", - "G187732-", - "A187733-", - "T187734-", - "T187735-", - "G187736-", - "T187737-", - "G187738-", - "A187739-", - "A187740-", - "C187741-", - "G187742-", - "A187743-", - "G187744-", - "A187745-", - "T187746-", - "T187747-", - "A187748-", - "A187749-", - "A187750-", - "T187751-", - "C187752-", - "A187753-", - "T187754-", - "C187755-", - "T187756-", - "A187757-", - "A187758-", - "C187759-", - "A187760-", - "A187761-", - "A187762-", - "T187763-", - "A187764-", - "A187765-", - "T187766-", - "T187767-", - "A187768-", - "G187769-", - "T187770-", - "T187771-", - "T187772-", - "T187773-", - "T187774-", - "T187775-", - "A187776-", - "T187777-", - "G187778-", - "A187779-", - "C187780-", - "A187781-", - "T187782-", - "T187783-", - "A187784-", - "A187785-", - "C187786-", - "A187787-", - "T187788-", - "A187789-", - "T187790-", - "A187791-", - "A187792-", - "T187793-", - "A187794-", - "A187795-", - "A187796-", - "T187797-", - "A187798-", - "A187799-", - "A187800-", - "T187801-", - "T187802-", - "A187803-", - "A187804-", - "T187805-", - "C187806-", - "A187807-", - "T187808-", - "T187809-", - "A187810-", - "T187811-", - "T187812-", - "G187813-", - "A187814-", - "C187815-", - "T187816-", - "T187817-", - "A187818-", - "A187819-", - "C187820-", - "G187821-", - "A187822-", - "T187823-", - "G187824-", - "A187825-", - "C187826-", - "G187827-", - "A187828-", - "A187829-", - "A187830-", - "G187831-", - "T187832-", - "T187833-", - "A187834-", - "T187835-", - "C187836-", - "A187837-", - "T187838-", - "T187839-", - "A187840-", - "T187841-", - "C187842-", - "T187843-", - "T187844-", - "A187845-", - "G187846-", - "G187847-", - "A187848-", - "T187849-", - "T187850-", - "C187851-", - "T187852-", - "T187853-", - "G187854-", - "A187855-", - "T187856-", - "T187857-", - "A187858-", - "T187859-", - "T187860-", - "A187861-", - "A187862-", - "T187863-", - "A187864-", - "C187865-", - "A187866-", - "A187867-", - "A187868-", - "T187869-", - "T187870-", - "C187871-", - "G187872-", - "T187873-", - "T187874-", - "G187875-", - "T187876-", - "G187877-", - "T187878-", - "C187879-", - "T187880-", - "A187881-", - "T187882-", - "G187883-", - "A187884-", - "A187885-", - "A187886-", - "T187887-", - "G187888-", - "T187889-", - "G187890-", - "A187891-", - "A187892-", - "C187893-", - "A187894-", - "A187895-", - "G187896-", - "G187897-", - "T187898-", - "G187899-", - "T187900-", - "C187901-", - "T187902-", - "C187903-", - "A187904-", - "T187905-", - "A187906-", - "T187907-", - "T187908-", - "A187909-", - "T187910-", - "A187911-", - "A187912-", - "T187913-", - "G187914-", - "C187915-", - "A187916-", - "C187917-", - "A187918-", - "A187919-", - "G187920-", - "A187921-", - "A187922-", - "T187923-", - "T187924-", - "A187925-", - "A187926-", - "A187927-", - "G187928-", - "T187929-", - "G187930-", - "T187931-", - "T187932-", - "G187933-", - "T187934-", - "A187935-", - "A187936-", - "A187937-", - "C187938-", - "T187939-", - "A187940-", - "T187941-", - "C187942-", - "T187943-", - "A187944-", - "G187945-", - "C187946-", - "C187947-", - "A187948-", - "G187949-", - "G187950-", - "A187951-", - "A187952-", - "C187953-", - "A187954-", - "T187955-", - "A187956-", - "T187957-", - "T187958-", - "C187959-", - "A187960-", - "G187961-", - "A187962-", - "T187963-", - "T187964-", - "A187965-", - "T187966-", - "C187967-", - "G187968-", - "A187969-", - "T187970-", - "G187971-", - "T187972-", - "G187973-", - "A187974-", - "T187975-", - "A187976-", - "A187977-", - "A187978-", - "T187979-", - "A187980-", - "C187981-", - "A187982-", - "G187983-", - "C187984-", - "G187985-", - "A187986-", - "T187987-", - "A187988-", - "C187989-", - "C187990-", - "A187991-", - "T187992-", - "C187993-", - "T187994-", - "G187995-", - "T187996-", - "G187997-", - "G187998-", - "A187999-", - "C188000-", - "A188001-", - "T188002-", - "T188003-", - "G188004-", - "T188005-", - "C188006-", - "C188007-", - "A188008-", - "A188009-", - "G188010-", - "T188011-", - "G188012-", - "A188013-", - "C188014-", - "A188015-", - "C188016-", - "A188017-", - "T188018-", - "T188019-", - "C188020-", - "A188021-", - "C188022-", - "G188023-", - "T188024-", - "C188025-", - "A188026-", - "A188027-", - "T188028-", - "A188029-", - "T188030-", - "A188031-", - "T188032-", - "A188033-", - "A188034-", - "T188035-", - "C188036-", - "G188037-", - "T188038-", - "T188039-", - "C188040-", - "T188041-", - "C188042-", - "C188043-", - "T188044-", - "C188045-", - "G188046-", - "G188047-", - "T188048-", - "G188049-", - "T188050-", - "C188051-", - "A188052-", - "T188053-", - "A188054-", - "G188055-", - "T188056-", - "T188057-", - "G188058-", - "T188059-", - "A188060-", - "G188061-", - "A188062-", - "G188063-", - "G188064-", - "T188065-", - "C188066-", - "A188067-", - "C188068-", - "A188069-", - "C188070-", - "C188071-", - "T188072-", - "T188073-", - "G188074-", - "T188075-", - "A188076-", - "C188077-", - "A188078-", - "C188079-", - "C188080-", - "T188081-", - "A188082-", - "C188083-", - "C188084-", - "A188085-", - "C188086-", - "A188087-", - "A188088-", - "A188089-", - "T188090-", - "A188091-", - "G188092-", - "A188093-", - "A188094-", - "T188095-", - "A188096-", - "T188097-", - "G188098-", - "T188099-", - "C188100-", - "A188101-", - "T188102-", - "T188103-", - "G188104-", - "T188105-", - "G188106-", - "A188107-", - "C188108-", - "T188109-", - "C188110-", - "G188111-", - "A188112-", - "A188113-", - "T188114-", - "A188115-", - "G188116-", - "T188117-", - "T188118-", - "A188119-", - "T188120-", - "C188121-", - "G188122-", - "T188123-", - "C188124-", - "T188125-", - "C188126-", - "C188127-", - "T188128-", - "T188129-", - "A188130-", - "A188131-", - "A188132-", - "G188133-", - "C188134-", - "T188135-", - "T188136-", - "C188137-", - "T188138-", - "G188139-", - "A188140-", - "T188141-", - "G188142-", - "G188143-", - "T188144-", - "A188145-", - "A188146-", - "C188147-", - "T188148-", - "G188149-", - "T188150-", - "G188151-", - "T188152-", - "T188153-", - "A188154-", - "C188155-", - "A188156-", - "T188157-", - "G188158-", - "T188159-", - "G188160-", - "C188161-", - "T188162-", - "C188163-", - "C188164-", - "T188165-", - "A188166-", - "A188167-", - "A188168-", - "A188169-", - "C188170-", - "A188171-", - "A188172-", - "A188173-", - "A188174-", - "T188175-", - "A188176-", - "T188177-", - "G188178-", - "G188179-", - "T188180-", - "C188181-", - "G188182-", - "T188183-", - "G188184-", - "T188185-", - "G188186-", - "T188187-", - "A188188-", - "C188189-", - "G188190-", - "G188191-", - "A188192-", - "A188193-", - "A188194-", - "G188195-", - "A188196-", - "A188197-", - "A188198-", - "G188199-", - "G188200-", - "A188201-", - "G188202-", - "A188203-", - "A188204-", - "A188205-", - "A188206-", - "T188207-", - "G188208-", - "A188209-", - "T188210-", - "A188211-", - "T188212-", - "G188213-", - "G188214-", - "A188215-", - "A188216-", - "T188217-", - "A188218-", - "C188219-", - "C188220-", - "A188221-", - "T188222-", - "T188223-", - "T188224-", - "G188225-", - "T188226-", - "A188227-", - "A188228-", - "G188229-", - "A188230-", - "A188231-", - "A188232-", - "T188233-", - "G188234-", - "T188235-", - "C188236-", - "G188237-", - "G188238-", - "A188239-", - "A188240-", - "G188241-", - "G188242-", - "G188243-", - "T188244-", - "A188245-", - "C188246-", - "T188247-", - "T188248-", - "A188249-", - "T188250-", - "T188251-", - "C188252-", - "A188253-", - "G188254-", - "A188255-", - "T188256-", - "A188257-", - "T188258-", - "T188259-", - "G188260-", - "T188261-", - "A188262-", - "T188263-", - "C188264-", - "T188265-", - "G188266-", - "A188267-", - "C188268-", - "T188269-", - "C188270-", - "T188271-", - "G188272-", - "A188273-", - "T188274-", - "C188275-", - "A188276-", - "A188277-", - "T188278-", - "G188279-", - "T188280-", - "A188281-", - "A188282-", - "A188283-", - "C188284-", - "C188285-", - "T188286-", - "A188287-", - "T188288-", - "G188289-", - "A188290-", - "C188291-", - "A188292-", - "A188293-", - "G188294-", - "A188295-", - "T188296-", - "A188297-", - "A188298-", - "G188299-", - "A188300-", - "C188301-", - "T188302-", - "T188303-", - "A188304-", - "C188305-", - "T188306-", - "C188307-", - "G188308-", - "C188309-", - "A188310-", - "T188311-", - "C188312-", - "T188313-", - "A188314-", - "C188315-", - "T188316-", - "G188317-", - "G188318-", - "A188319-", - "T188320-", - "A188321-", - "G188322-", - "A188323-", - "C188324-", - "A188325-", - "T188326-", - "A188327-", - "A188328-", - "A188329-", - "T188330-", - "A188331-", - "T188332-", - "C188333-", - "C188334-", - "T188335-", - "C188336-", - "C188337-", - "T188338-", - "C188339-", - "G188340-", - "T188341-", - "A188342-", - "A188343-", - "T188344-", - "A188345-", - "A188346-", - "T188347-", - "G188348-", - "A188349-", - "A188350-", - "A188351-", - "T188352-", - "A188353-", - "T188354-", - "A188355-", - "A188356-", - "T188357-", - "A188358-", - "T188359-", - "A188360-", - "C188361-", - "A188362-", - "C188363-", - "T188364-", - "A188365-", - "A188366-", - "T188367-", - "T188368-", - "A188369-", - "T188370-", - "T188371-", - "A188372-", - "A188373-", - "T188374-", - "A188375-", - "T188376-", - "C188377-", - "A188378-", - "A188379-", - "T188380-", - "C188381-", - "G188382-", - "A188383-", - "G188384-", - "T188385-", - "A188386-", - "T188387-", - "T188388-", - "A188389-", - "A188390-", - "C188391-", - "A188392-", - "T188393-", - "A188394-", - "T188395-", - "A188396-", - "A188397-", - "G188398-", - "T188399-", - "T188400-", - "A188401-", - "T188402-", - "T188403-", - "T188404-", - "T188405-", - "T188406-", - "A188407-", - "A188408-", - "A188409-", - "C188410-", - "C188411-", - "C188412-", - "C188413-", - "T188414-", - "T188415-", - "T188416-", - "T188417-", - "G188418-", - "G188419-", - "G188420-", - "T188421-", - "T188422-", - "C188423-", - "C188424-", - "G188425-", - "T188426-", - "C188427-", - "C188428-", - "T188429-", - "A188430-", - "A188431-", - "A188432-", - "C188433-", - "G188434-", - "G188435-", - "C188436-", - "G188437-", - "T188438-", - "T188439-", - "T188440-", - "C188441-", - "G188442-", - "G188443-", - "T188444-", - "C188445-", - "T188446-", - "G188447-", - "T188448-", - "G188449-", - "T188450-", - "C188451-", - "G188452-", - "C188453-", - "C188454-", - "A188455-", - "C188456-", - "C188457-", - "A188458-", - "T188459-", - "G188460-", - "G188461-", - "T188462-", - "C188463-", - "A188464-", - "C188465-", - "A188466-", - "C188467-", - "C188468-", - "G188469-", - "A188470-", - "G188471-", - "C188472-", - "C188473-", - "T188474-", - "C188475-", - "T188476-", - "G188477-", - "C188478-", - "G188479-", - "T188480-", - "G188481-", - "C188482-", - "T188483-", - "C188484-", - "C188485-", - "T188486-", - "C188487-", - "C188488-", - "A188489-", - "T188490-", - "C188491-", - "G188492-", - "A188493-", - "G188494-", - "G188495-", - "A188496-", - "C188497-", - "G188498-", - "A188499-", - "C188500-", - "T188501-", - "T188502-", - "C188503-", - "A188504-", - "A188505-", - "C188506-", - "T188507-", - "A188508-", - "T188509-", - "G188510-", - "A188511-", - "C188512-", - "A188513-", - "G188514-", - "C188515-", - "T188516-", - "C188517-", - "G188518-", - "G188519-", - "T188520-", - "G188521-", - "G188522-", - "C188523-", - "G188524-", - "T188525-", - "C188526-", - "T188527-", - "G188528-", - "C188529-", - "C188530-", - "A188531-", - "G188532-", - "C188533-", - "G188534-", - "T188535-", - "G188536-", - "T188537-", - "A188538-", - "C188539-", - "A188540-", - "T188541-", - "A188542-", - "C188543-", - "G188544-", - "A188545-", - "A188546-", - "T188547-", - "G188548-", - "G188549-", - "C188550-", - "A188551-", - "T188552-", - "T188553-", - "T188554-", - "C188555-", - "T188556-", - "A188557-", - "A188558-", - "G188559-", - "A188560-", - "A188561-", - "A188562-", - "A188563-", - "G188564-", - "T188565-", - "C188566-", - "T188567-", - "A188568-", - "C188569-", - "G188570-", - "G188571-", - "T188572-", - "A188573-", - "T188574-", - "C188575-", - "C188576-", - "T188577-", - "T188578-", - "T188579-", - "C188580-", - "T188581-", - "A188582-", - "C188583-", - "A188584-", - "A188585-", - "T188586-", - "T188587-", - "T188588-", - "C188589-", - "C188590-", - "T188591-", - "T188592-", - "T188593-", - "A188594-", - "A188595-", - "C188596-", - "A188597-", - "A188598-", - "C188599-", - "G188600-", - "G188601-", - "C188602-", - "A188603-", - "A188604-", - "C188605-", - "A188606-", - "G188607-", - "C188608-", - "T188609-", - "G188610-", - "C188611-", - "A188612-", - "G188613-", - "T188614-", - "A188615-", - "T188616-", - "T188617-", - "T188618-", - "T188619-", - "T188620-", - "A188621-", - "T188622-", - "A188623-", - "C188624-", - "T188625-", - "T188626-", - "T188627-", - "G188628-", - "A188629-", - "A188630-", - "T188631-", - "G188632-", - "C188633-", - "A188634-", - "T188635-", - "C188636-", - "G188637-", - "G188638-", - "A188639-", - "C188640-", - "A188641-", - "T188642-", - "T188643-", - "T188644-", - "A188645-", - "T188646-", - "A188647-", - "C188648-", - "A188649-", - "A188650-", - "G188651-", - "G188652-", - "G188653-", - "A188654-", - "G188655-", - "T188656-", - "C188657-", - "C188658-", - "T188659-", - "G188660-", - "T188661-", - "T188662-", - "C188663-", - "T188664-", - "A188665-", - "A188666-", - "T188667-", - "A188668-", - "T188669-", - "T188670-", - "G188671-", - "G188672-", - "C188673-", - "A188674-", - "T188675-", - "C188676-", - "A188677-", - "A188678-", - "T188679-", - "G188680-", - "T188681-", - "T188682-", - "C188683-", - "G188684-", - "G188685-", - "A188686-", - "T188687-", - "C188688-", - "T188689-", - "A188690-", - "T188691-", - "A188692-", - "G188693-", - "G188694-", - "C188695-", - "T188696-", - "T188697-", - "G188698-", - "A188699-", - "T188700-", - "T188701-", - "T188702-", - "T188703-", - "C188704-", - "G188705-", - "C188706-", - "A188707-", - "T188708-", - "T188709-", - "G188710-", - "A188711-", - "C188712-", - "T188713-", - "T188714-", - "T188715-", - "A188716-", - "C188717-", - "A188718-", - "C188719-", - "A188720-", - "G188721-", - "A188722-", - "C188723-", - "A188724-", - "T188725-", - "G188726-", - "A188727-", - "A188728-", - "C188729-", - "A188730-", - "T188731-", - "C188732-", - "C188733-", - "C188734-", - "C188735-", - "T188736-", - "G188737-", - "A188738-", - "A188739-", - "T188740-", - "C188741-", - "T188742-", - "G188743-", - "T188744-", - "A188745-", - "C188746-", - "A188747-", - "T188748-", - "A188749-", - "C188750-", - "T188751-", - "T188752-", - "T188753-", - "G188754-", - "T188755-", - "G188756-", - "G188757-", - "A188758-", - "T188759-", - "T188760-", - "T188761-", - "A188762-", - "C188763-", - "A188764-", - "C188765-", - "T188766-", - "G188767-", - "T188768-", - "T188769-", - "A188770-", - "G188771-", - "A188772-", - "A188773-", - "T188774-", - "C188775-", - "T188776-", - "C188777-", - "T188778-", - "A188779-", - "A188780-", - "C188781-", - "G188782-", - "C188783-", - "T188784-", - "G188785-", - "G188786-", - "C188787-", - "C188788-", - "T188789-", - "C188790-", - "T188791-", - "G188792-", - "T188793-", - "T188794-", - "G188795-", - "T188796-", - "T188797-", - "A188798-", - "C188799-", - "T188800-", - "T188801-", - "T188802-", - "C188803-", - "T188804-", - "A188805-", - "T188806-", - "G188807-", - "A188808-", - "T188809-", - "G188810-", - "C188811-", - "A188812-", - "C188813-", - "G188814-", - "T188815-", - "A188816-", - "T188817-", - "C188818-", - "G188819-", - "T188820-", - "T188821-", - "A188822-", - "T188823-", - "G188824-", - "C188825-", - "A188826-", - "A188827-", - "G188828-", - "C188829-", - "T188830-", - "T188831-", - "T188832-", - "C188833-", - "A188834-", - "T188835-", - "G188836-", - "T188837-", - "T188838-", - "G188839-", - "A188840-", - "C188841-", - "T188842-", - "A188843-", - "C188844-", - "T188845-", - "G188846-", - "C188847-", - "A188848-", - "G188849-", - "T188850-", - "G188851-", - "T188852-", - "T188853-", - "T188854-", - "C188855-", - "T188856-", - "T188857-", - "G188858-", - "C188859-", - "T188860-", - "C188861-", - "T188862-", - "G188863-", - "A188864-", - "C188865-", - "T188866-", - "A188867-", - "C188868-", - "A188869-", - "T188870-", - "A188871-", - "T188872-", - "A188873-", - "C188874-", - "T188875-", - "C188876-", - "T188877-", - "A188878-", - "C188879-", - "A188880-", - "A188881-", - "T188882-", - "C188883-", - "A188884-", - "A188885-", - "A188886-", - "G188887-", - "A188888-", - "G188889-", - "A188890-", - "G188891-", - "A188892-", - "T188893-", - "T188894-", - "T188895-", - "C188896-", - "A188897-", - "G188898-", - "T188899-", - "A188900-", - "A188901-", - "A188902-", - "C188903-", - "T188904-", - "T188905-", - "G188906-", - "T188907-", - "A188908-", - "A188909-", - "C188910-", - "A188911-", - "G188912-", - "G188913-", - "A188914-", - "T188915-", - "T188916-", - "G188917-", - "T188918-", - "T188919-", - "T188920-", - "G188921-", - "C188922-", - "T188923-", - "G188924-", - "C188925-", - "T188926-", - "T188927-", - "T188928-", - "C188929-", - "T188930-", - "G188931-", - "G188932-", - "A188933-", - "T188934-", - "T188935-", - "T188936-", - "T188937-", - "A188938-", - "A188939-", - "T188940-", - "T188941-", - "T188942-", - "T188943-", - "G188944-", - "T188945-", - "C188946-", - "A188947-", - "G188948-", - "G188949-", - "A188950-", - "G188951-", - "T188952-", - "C188953-", - "T188954-", - "T188955-", - "G188956-", - "A188957-", - "G188958-", - "G188959-", - "A188960-", - "T188961-", - "A188962-", - "A188963-", - "A188964-", - "G188965-", - "T188966-", - "T188967-", - "T188968-", - "A188969-", - "A188970-", - "A188971-", - "A188972-", - "T188973-", - "A188974-", - "G188975-", - "A188976-", - "A188977-", - "T188978-", - "T188979-", - "A188980-", - "A188981-", - "T188982-", - "A188983-", - "A188984-", - "A188985-", - "G188986-", - "A188987-", - "A188988-", - "C188989-", - "A188990-", - "T188991-", - "A188992-", - "T188993-", - "A188994-", - "G188995-", - "G188996-", - "T188997-", - "C188998-", - "A188999-", - "T189000-", - "T189001-", - "T189002-", - "T189003-", - "T189004-", - "T189005-", - "A189006-", - "A189007-", - "A189008-", - "C189009-", - "A189010-", - "T189011-", - "G189012-", - "G189013-", - "A189014-", - "T189015-", - "A189016-", - "G189017-", - "A189018-", - "A189019-", - "A189020-", - "C189021-", - "C189022-", - "A189023-", - "A189024-", - "G189025-", - "G189026-", - "T189027-", - "T189028-", - "G189029-", - "T189030-", - "T189031-", - "A189032-", - "G189033-", - "T189034-", - "T189035-", - "A189036-", - "A189037-", - "T189038-", - "A189039-", - "A189040-", - "T189041-", - "A189042-", - "T189043-", - "A189044-", - "C189045-", - "A189046-", - "A189047-", - "G189048-", - "A189049-", - "T189050-", - "A189051-", - "T189052-", - "T189053-", - "T189054-", - "T189055-", - "T189056-", - "T189057-", - "C189058-", - "T189059-", - "C189060-", - "A189061-", - "C189062-", - "T189063-", - "C189064-", - "T189065-", - "G189066-", - "A189067-", - "T189068-", - "C189069-", - "C189070-", - "A189071-", - "T189072-", - "G189073-", - "T189074-", - "A189075-", - "A189076-", - "A189077-", - "C189078-", - "C189079-", - "A189080-", - "A189081-", - "G189082-", - "G189083-", - "A189084-", - "C189085-", - "G189086-", - "A189087-", - "G189088-", - "A189089-", - "G189090-", - "A189091-", - "C189092-", - "A189093-", - "C189094-", - "T189095-", - "C189096-", - "T189097-", - "C189098-", - "A189099-", - "T189100-", - "T189101-", - "C189102-", - "C189103-", - "T189104-", - "C189105-", - "A189106-", - "T189107-", - "T189108-", - "C189109-", - "A189110-", - "C189111-", - "G189112-", - "A189113-", - "C189114-", - "A189115-", - "C189116-", - "C189117-", - "A189118-", - "T189119-", - "T189120-", - "A189121-", - "A189122-", - "A189123-", - "A189124-", - "A189125-", - "T189126-", - "G189127-", - "G189128-", - "A189129-", - "A189130-", - "A189131-", - "T189132-", - "T189133-", - "A189134-", - "A189135-", - "A189136-", - "G189137-", - "C189138-", - "C189139-", - "C189140-", - "T189141-", - "C189142-", - "T189143-", - "A189144-", - "T189145-", - "T189146-", - "A189147-", - "A189148-", - "G189149-", - "C189150-", - "A189151-", - "C189152-", - "A189153-", - "G189154-", - "A189155-", - "C189156-", - "G189157-", - "G189158-", - "C189159-", - "T189160-", - "A189161-", - "C189162-", - "A189163-", - "G189164-", - "G189165-", - "T189166-", - "C189167-", - "T189168-", - "A189169-", - "C189170-", - "C189171-", - "A189172-", - "T189173-", - "C189174-", - "A189175-", - "G189176-", - "G189177-", - "T189178-", - "T189179-", - "A189180-", - "C189181-", - "C189182-", - "T189183-", - "T189184-", - "C189185-", - "G189186-", - "T189187-", - "C189188-", - "T189189-", - "A189190-", - "C189191-", - "C189192-", - "T189193-", - "T189194-", - "C189195-", - "A189196-", - "C189197-", - "A189198-", - "A189199-", - "T189200-", - "G189201-", - "G189202-", - "C189203-", - "C189204-", - "T189205-", - "C189206-", - "T189207-", - "C189208-", - "C189209-", - "T189210-", - "T189211-", - "G189212-", - "T189213-", - "G189214-", - "C189215-", - "C189216-", - "C189217-", - "A189218-", - "G189219-", - "T189220-", - "T189221-", - "C189222-", - "A189223-", - "G189224-", - "T189225-", - "C189226-", - "C189227-", - "C189228-", - "T189229-", - "G189230-", - "T189231-", - "C189232-", - "A189233-", - "T189234-", - "T189235-", - "G189236-", - "C189237-", - "C189238-", - "A189239-", - "C189240-", - "G189241-", - "C189242-", - "T189243-", - "A189244-", - "C189245-", - "T189246-", - "A189247-", - "A189248-", - "G189249-", - "G189250-", - "A189251-", - "C189252-", - "T189253-", - "C189254-", - "C189255-", - "C189256-", - "T189257-", - "G189258-", - "A189259-", - "A189260-", - "T189261-", - "A189262-", - "C189263-", - "C189264-", - "G189265-", - "T189266-", - "G189267-", - "A189268-", - "C189269-", - "T189270-", - "G189271-", - "A189272-", - "C189273-", - "G189274-", - "T189275-", - "C189276-", - "A189277-", - "G189278-", - "A189279-", - "C189280-", - "A189281-", - "T189282-", - "T189283-", - "G189284-", - "T189285-", - "C189286-", - "T189287-", - "G189288-", - "A189289-", - "C189290-", - "T189291-", - "G189292-", - "A189293-", - "A189294-", - "T189295-", - "A189296-", - "C189297-", - "A189298-", - "T189299-", - "C189300-", - "C189301-", - "T189302-", - "G189303-", - "T189304-", - "G189305-", - "G189306-", - "G189307-", - "T189308-", - "T189309-", - "T189310-", - "C189311-", - "T189312-", - "C189313-", - "A189314-", - "T189315-", - "A189316-", - "G189317-", - "A189318-", - "T189319-", - "G189320-", - "G189321-", - "A189322-", - "C189323-", - "C189324-", - "C189325-", - "A189326-", - "T189327-", - "A189328-", - "G189329-", - "A189330-", - "G189331-", - "A189332-", - "A189333-", - "A189334-", - "G189335-", - "C189336-", - "G189337-", - "C189338-", - "A189339-", - "G189340-", - "G189341-", - "G189342-", - "C189343-", - "C189344-", - "T189345-", - "C189346-", - "T189347-", - "C189348-", - "T189349-", - "A189350-", - "C189351-", - "A189352-", - "G189353-", - "G189354-", - "C189355-", - "T189356-", - "T189357-", - "C189358-", - "T189359-", - "C189360-", - "A189361-", - "T189362-", - "C189363-", - "T189364-", - "C189365-", - "T189366-", - "T189367-", - "T189368-", - "C189369-", - "A189370-", - "G189371-", - "A189372-", - "A189373-", - "T189374-", - "T189375-", - "G189376-", - "A189377-", - "T189378-", - "G189379-", - "C189380-", - "A189381-", - "A189382-", - "T189383-", - "G189384-", - "G189385-", - "A189386-", - "G189387-", - "C189388-", - "T189389-", - "A189390-", - "T189391-", - "T189392-", - "T189393-", - "G189394-", - "G189395-", - "T189396-", - "A189397-", - "G189398-", - "C189399-", - "G189400-", - "A189401-", - "G189402-", - "T189403-", - "T189404-", - "G189405-", - "A189406-", - "A189407-", - "G189408-", - "G189409-", - "A189410-", - "G189411-", - "T189412-", - "T189413-", - "C189414-", - "T189415-", - "C189416-", - "G189417-", - "A189418-", - "A189419-", - "T189420-", - "T189421-", - "C189422-", - "A189423-", - "C189424-", - "T189425-", - "T189426-", - "C189427-", - "C189428-", - "G189429-", - "T189430-", - "G189431-", - "G189432-", - "G189433-", - "A189434-", - "C189435-", - "A189436-", - "A189437-", - "T189438-", - "A189439-", - "T189440-", - "C189441-", - "G189442-", - "A189443-", - "C189444-", - "A189445-", - "A189446-", - "T189447-", - "T189448-", - "G189449-", - "C189450-", - "G189451-", - "T189452-", - "G189453-", - "G189454-", - "A189455-", - "G189456-", - "A189457-", - "T189458-", - "C189459-", - "A189460-", - "T189461-", - "T189462-", - "A189463-", - "A189464-", - "A189465-", - "T189466-", - "G189467-", - "T189468-", - "T189469-", - "T189470-", - "C189471-", - "A189472-", - "T189473-", - "C189474-", - "A189475-", - "G189476-", - "A189477-", - "A189478-", - "A189479-", - "T189480-", - "G189481-", - "A189482-", - "C189483-", - "T189484-", - "C189485-", - "C189486-", - "A189487-", - "T189488-", - "G189489-", - "A189490-", - "A189491-", - "A189492-", - "A189493-", - "C189494-", - "C189495-", - "G189496-", - "C189497-", - "C189498-", - "A189499-", - "A189500-", - "A189501-", - "G189502-", - "A189503-", - "A189504-", - "C189505-", - "T189506-", - "T189507-", - "T189508-", - "G189509-", - "T189510-", - "G189511-", - "C189512-", - "A189513-", - "A189514-", - "T189515-", - "A189516-", - "A189517-", - "T189518-", - "T189519-", - "G189520-", - "G189521-", - "A189522-", - "C189523-", - "T189524-", - "T189525-", - "T189526-", - "G189527-", - "T189528-", - "A189529-", - "C189530-", - "T189531-", - "C189532-", - "A189533-", - "A189534-", - "T189535-", - "C189536-", - "A189537-", - "G189538-", - "C189539-", - "T189540-", - "A189541-", - "T189542-", - "T189543-", - "G189544-", - "T189545-", - "C189546-", - "A189547-", - "C189548-", - "T189549-", - "G189550-", - "G189551-", - "A189552-", - "A189553-", - "G189554-", - "A189555-", - "G189556-", - "T189557-", - "C189558-", - "T189559-", - "T189560-", - "C189561-", - "A189562-", - "A189563-", - "T189564-", - "G189565-", - "A189566-", - "T189567-", - "A189568-", - "A189569-", - "G189570-", - "T189571-", - "A189572-", - "T189573-", - "A189574-", - "T189575-", - "C189576-", - "G189577-", - "A189578-", - "C189579-", - "A189580-", - "T189581-", - "A189582-", - "C189583-", - "T189584-", - "A189585-", - "C189586-", - "T189587-", - "T189588-", - "A189589-", - "T189590-", - "G189591-", - "C189592-", - "T189593-", - "G189594-", - "C189595-", - "G189596-", - "A189597-", - "A189598-", - "A189599-", - "G189600-", - "A189601-", - "T189602-", - "T189603-", - "C189604-", - "T189605-", - "G189606-", - "A189607-", - "A189608-", - "C189609-", - "G189610-", - "A189611-", - "G189612-", - "A189613-", - "A189614-", - "C189615-", - "G189616-", - "A189617-", - "C189618-", - "T189619-", - "A189620-", - "T189621-", - "C189622-", - "T189623-", - "C189624-", - "A189625-", - "C189626-", - "C189627-", - "C189628-", - "T189629-", - "C189630-", - "T189631-", - "T189632-", - "G189633-", - "G189634-", - "A189635-", - "T189636-", - "C189637-", - "A189638-", - "T189639-", - "A189640-", - "T189641-", - "C189642-", - "C189643-", - "T189644-", - "C189645-", - "A189646-", - "C189647-", - "T189648-", - "G189649-", - "C189650-", - "T189651-", - "A189652-", - "A189653-", - "A189654-", - "T189655-", - "A189656-", - "C189657-", - "T189658-", - "A189659-", - "A189660-", - "A189661-", - "T189662-", - "C189663-", - "T189664-", - "C189665-", - "C189666-", - "T189667-", - "T189668-", - "C189669-", - "A189670-", - "T189671-", - "G189672-", - "C189673-", - "T189674-", - "C189675-", - "T189676-", - "C189677-", - "T189678-", - "C189679-", - "A189680-", - "C189681-", - "T189682-", - "A189683-", - "A189684-", - "T189685-", - "A189686-", - "C189687-", - "T189688-", - "C189689-", - "T189690-", - "T189691-", - "A189692-", - "C189693-", - "T189694-", - "C189695-", - "A189696-", - "C189697-", - "T189698-", - "A189699-", - "C189700-", - "A189701-", - "C189702-", - "T189703-", - "T189704-", - "T189705-", - "T189706-", - "T189707-", - "A189708-", - "T189709-", - "C189710-", - "A189711-", - "T189712-", - "C189713-", - "T189714-", - "T189715-", - "A189716-", - "T189717-", - "G189718-", - "A189719-", - "T189720-", - "G189721-", - "A189722-", - "A189723-", - "T189724-", - "G189725-", - "A189726-", - "T189727-", - "T189728-", - "G189729-", - "C189730-", - "C189731-", - "T189732-", - "T189733-", - "C189734-", - "A189735-", - "T189736-", - "C189737-", - "A189738-", - "T189739-", - "T189740-", - "T189741-", - "T189742-", - "T189743-", - "T189744-", - "C189745-", - "G189746-", - "T189747-", - "G189748-", - "G189749-", - "A189750-", - "A189751-", - "T189752-", - "A189753-", - "T189754-", - "A189755-", - "A189756-", - "T189757-", - "A189758-", - "T189759-", - "A189760-", - "G189761-", - "G189762-", - "A189763-", - "A189764-", - "T189765-", - "A189766-", - "A189767-", - "T189768-", - "T189769-", - "A189770-", - "G189771-", - "C189772-", - "A189773-", - "C189774-", - "C189775-", - "A189776-", - "G189777-", - "A189778-", - "A189779-", - "T189780-", - "A189781-", - "G189782-", - "C189783-", - "T189784-", - "A189785-", - "T189786-", - "G189787-", - "G189788-", - "A189789-", - "T189790-", - "A189791-", - "T189792-", - "C189793-", - "T189794-", - "C189795-", - "G189796-", - "T189797-", - "T189798-", - "A189799-", - "A189800-", - "G189801-", - "A189802-", - "A189803-", - "T189804-", - "A189805-", - "T189806-", - "T189807-", - "C189808-", - "T189809-", - "C189810-", - "T189811-", - "A189812-", - "T189813-", - "A189814-", - "A189815-", - "G189816-", - "A189817-", - "G189818-", - "A189819-", - "C189820-", - "A189821-", - "T189822-", - "A189823-", - "A189824-", - "T189825-", - "G189826-", - "T189827-", - "A189828-", - "G189829-", - "A189830-", - "C189831-", - "A189832-", - "T189833-", - "A189834-", - "G189835-", - "T189836-", - "T189837-", - "A189838-", - "T189839-", - "T189840-", - "A189841-", - "T189842-", - "A189843-", - "T189844-", - "C189845-", - "C189846-", - "T189847-", - "T189848-", - "C189849-", - "T189850-", - "T189851-", - "A189852-", - "G189853-", - "A189854-", - "T189855-", - "A189856-", - "A189857-", - "G189858-", - "T189859-", - "G189860-", - "T189861-", - "T189862-", - "A189863-", - "C189864-", - "G189865-", - "C189866-", - "T189867-", - "A189868-", - "C189869-", - "T189870-", - "G189871-", - "G189872-", - "A189873-", - "A189874-", - "A189875-", - "G189876-", - "T189877-", - "T189878-", - "T189879-", - "C189880-", - "C189881-", - "A189882-", - "T189883-", - "C189884-", - "G189885-", - "T189886-", - "T189887-", - "A189888-", - "T189889-", - "T189890-", - "A189891-", - "T189892-", - "T189893-", - "A189894-", - "C189895-", - "A189896-", - "T189897-", - "G189898-", - "A189899-", - "A189900-", - "G189901-", - "A189902-", - "T189903-", - "G189904-", - "A189905-", - "T189906-", - "A189907-", - "T189908-", - "A189909-", - "A189910-", - "T189911-", - "T189912-", - "A189913-", - "A189914-", - "A189915-", - "C189916-", - "C189917-", - "A189918-", - "A189919-", - "C189920-", - "A189921-", - "T189922-", - "T189923-", - "G189924-", - "A189925-", - "G189926-", - "A189927-", - "T189928-", - "T189929-", - "G189930-", - "G189931-", - "C189932-", - "T189933-", - "C189934-", - "T189935-", - "T189936-", - "A189937-", - "T189938-", - "G189939-", - "T189940-", - "T189941-", - "A189942-", - "G189943-", - "C189944-", - "T189945-", - "G189946-", - "G189947-", - "A189948-", - "T189949-", - "T189950-", - "G189951-", - "A189952-", - "A189953-", - "T189954-", - "T189955-", - "A189956-", - "C189957-", - "T189958-", - "G189959-", - "T189960-", - "A189961-", - "A189962-", - "T189963-", - "A189964-", - "A189965-", - "A189966-", - "T189967-", - "G189968-", - "C189969-", - "A189970-", - "T189971-", - "C189972-", - "G189973-", - "A189974-", - "G189975-", - "T189976-", - "A189977-", - "T189978-", - "A189979-", - "G189980-", - "A189981-", - "G189982-", - "G189983-", - "G189984-", - "A189985-", - "T189986-", - "A189987-", - "T189988-", - "A189989-", - "G189990-", - "C189991-", - "A189992-", - "A189993-", - "T189994-", - "T189995-", - "C189996-", - "T189997-", - "C189998-", - "G189999-", - "A190000-", - "T190001-", - "A190002-", - "A190003-", - "T190004-", - "A190005-", - "G190006-", - "T190007-", - "C190008-", - "A190009-", - "T190010-", - "G190011-", - "C190012-", - "A190013-", - "A190014-", - "T190015-", - "A190016-", - "T190017-", - "T190018-", - "T190019-", - "G190020-", - "A190021-", - "A190022-", - "T190023-", - "G190024-", - "A190025-", - "G190026-", - "A190027-", - "C190028-", - "T190029-", - "G190030-", - "A190031-", - "T190032-", - "A190033-", - "A190034-", - "T190035-", - "T190036-", - "T190037-", - "A190038-", - "G190039-", - "G190040-", - "T190041-", - "A190042-", - "A190043-", - "T190044-", - "A190045-", - "C190046-", - "A190047-", - "G190048-", - "T190049-", - "A190050-", - "C190051-", - "T190052-", - "A190053-", - "C190054-", - "A190055-", - "C190056-", - "A190057-", - "C190058-", - "A190059-", - "T190060-", - "A190061-", - "T190062-", - "C190063-", - "T190064-", - "T190065-", - "T190066-", - "C190067-", - "T190068-", - "A190069-", - "G190070-", - "A190071-", - "T190072-", - "T190073-", - "A190074-", - "T190075-", - "A190076-", - "T190077-", - "A190078-", - "T190079-", - "C190080-", - "G190081-", - "T190082-", - "T190083-", - "A190084-", - "A190085-", - "A190086-", - "A190087-", - "A190088-", - "T190089-", - "C190090-", - "T190091-", - "G190092-", - "T190093-", - "A190094-", - "A190095-", - "G190096-", - "A190097-", - "T190098-", - "G190099-", - "T190100-", - "A190101-", - "T190102-", - "A190103-", - "T190104-", - "T190105-", - "T190106-", - "C190107-", - "T190108-", - "C190109-", - "A190110-", - "T190111-", - "A190112-", - "A190113-", - "G190114-", - "T190115-", - "A190116-", - "T190117-", - "C190118-", - "C190119-", - "A190120-", - "C190121-", - "T190122-", - "G190123-", - "T190124-", - "G190125-", - "T190126-", - "A190127-", - "A190128-", - "T190129-", - "A190130-", - "T190131-", - "T190132-", - "A190133-", - "T190134-", - "T190135-", - "A190136-", - "A190137-", - "T190138-", - "G190139-", - "G190140-", - "A190141-", - "T190142-", - "A190143-", - "T190144-", - "A190145-", - "T190146-", - "A190147-", - "G190148-", - "A190149-", - "T190150-", - "A190151-", - "A190152-", - "C190153-", - "G190154-", - "C190155-", - "A190156-", - "A190157-", - "T190158-", - "A190159-", - "G190160-", - "G190161-", - "G190162-", - "A190163-", - "C190164-", - "T190165-", - "A190166-", - "A190167-", - "T190168-", - "A190169-", - "G190170-", - "T190171-", - "A190172-", - "T190173-", - "T190174-", - "G190175-", - "T190176-", - "A190177-", - "A190178-", - "A190179-", - "A190180-", - "G190181-", - "A190182-", - "T190183-", - "A190184-", - "T190185-", - "A190186-", - "A190187-", - "T190188-", - "C190189-", - "G190190-", - "A190191-", - "C190192-", - "T190193-", - "A190194-", - "T190195-", - "T190196-", - "T190197-", - "A190198-", - "C190199-", - "G190200-", - "T190201-", - "A190202-", - "C190203-", - "A190204-", - "T190205-", - "A190206-", - "T190207-", - "C190208-", - "C190209-", - "A190210-", - "G190211-", - "A190212-", - "T190213-", - "A190214-", - "T190215-", - "C190216-", - "T190217-", - "A190218-", - "T190219-", - "A190220-", - "T190221-", - "T190222-", - "C190223-", - "C190224-", - "T190225-", - "A190226-", - "C190227-", - "T190228-", - "A190229-", - "G190230-", - "T190231-", - "T190232-", - "T190233-", - "G190234-", - "C190235-", - "T190236-", - "G190237-", - "C190238-", - "G190239-", - "T190240-", - "A190241-", - "G190242-", - "T190243-", - "T190244-", - "G190245-", - "C190246-", - "A190247-", - "T190248-", - "C190249-", - "A190250-", - "T190251-", - "T190252-", - "G190253-", - "A190254-", - "T190255-", - "A190256-", - "T190257-", - "G190258-", - "C190259-", - "A190260-", - "T190261-", - "G190262-", - "A190263-", - "T190264-", - "T190265-", - "T190266-", - "A190267-", - "T190268-", - "C190269-", - "A190270-", - "G190271-", - "G190272-", - "A190273-", - "T190274-", - "T190275-", - "C190276-", - "A190277-", - "G190278-", - "A190279-", - "G190280-", - "A190281-", - "T190282-", - "G190283-", - "A190284-", - "A190285-", - "T190286-", - "T190287-", - "A190288-", - "C190289-", - "T190290-", - "A190291-", - "A190292-", - "G190293-", - "T190294-", - "A190295-", - "A190296-", - "A190297-", - "C190298-", - "T190299-", - "A190300-", - "C190301-", - "A190302-", - "A190303-", - "T190304-", - "C190305-", - "C190306-", - "C190307-", - "A190308-", - "C190309-", - "A190310-", - "A190311-", - "T190312-", - "A190313-", - "A190314-", - "G190315-", - "T190316-", - "A190317-", - "A190318-", - "G190319-", - "A190320-", - "A190321-", - "T190322-", - "C190323-", - "A190324-", - "A190325-", - "A190326-", - "T190327-", - "A190328-", - "T190329-", - "C190330-", - "A190331-", - "A190332-", - "A190333-", - "A190334-", - "A190335-", - "C190336-", - "T190337-", - "C190338-", - "A190339-", - "C190340-", - "T190341-", - "T190342-", - "T190343-", - "T190344-", - "G190345-", - "A190346-", - "T190347-", - "T190348-", - "T190349-", - "T190350-", - "T190351-", - "C190352-", - "T190353-", - "A190354-", - "G190355-", - "T190356-", - "C190357-", - "T190358-", - "T190359-", - "A190360-", - "A190361-", - "G190362-", - "T190363-", - "A190364-", - "A190365-", - "T190366-", - "A190367-", - "C190368-", - "A190369-", - "T190370-", - "A190371-", - "T190372-", - "A190373-", - "T190374-", - "T190375-", - "T190376-", - "A190377-", - "T190378-", - "T190379-", - "A190380-", - "A190381-", - "T190382-", - "A190383-", - "G190384-", - "A190385-", - "C190386-", - "C190387-", - "T190388-", - "A190389-", - "T190390-", - "G190391-", - "A190392-", - "A190393-", - "A190394-", - "T190395-", - "A190396-", - "A190397-", - "A190398-", - "A190399-", - "A190400-", - "A190401-", - "A190402-", - "G190403-", - "G190404-", - "T190405-", - "A190406-", - "A190407-", - "C190408-", - "A190409-", - "A190410-", - "T190411-", - "G190412-", - "G190413-", - "A190414-", - "T190415-", - "T190416-", - "C190417-", - "G190418-", - "C190419-", - "G190420-", - "T190421-", - "A190422-", - "T190423-", - "A190424-", - "G190425-", - "C190426-", - "T190427-", - "A190428-", - "T190429-", - "T190430-", - "T190431-", - "A190432-", - "C190433-", - "G190434-", - "T190435-", - "A190436-", - "T190437-", - "T190438-", - "A190439-", - "G190440-", - "T190441-", - "A190442-", - "T190443-", - "C190444-", - "G190445-", - "G190446-", - "C190447-", - "A190448-", - "T190449-", - "C190450-", - "T190451-", - "C190452-", - "T190453-", - "T190454-", - "T190455-", - "T190456-", - "G190457-", - "T190458-", - "A190459-", - "T190460-", - "C190461-", - "T190462-", - "T190463-", - "G190464-", - "T190465-", - "T190466-", - "A190467-", - "A190468-", - "T190469-", - "T190470-", - "G190471-", - "T190472-", - "C190473-", - "A190474-", - "C190475-", - "A190476-", - "A190477-", - "A190478-", - "C190479-", - "T190480-", - "A190481-", - "G190482-", - "T190483-", - "A190484-", - "C190485-", - "A190486-", - "T190487-", - "T190488-", - "A190489-", - "C190490-", - "T190491-", - "T190492-", - "C190493-", - "A190494-", - "A190495-", - "T190496-", - "C190497-", - "T190498-", - "G190499-", - "A190500-", - "A190501-", - "A190502-", - "A190503-", - "T190504-", - "A190505-", - "A190506-", - "A190507-", - "T190508-", - "G190509-", - "G190510-", - "A190511-", - "A190512-", - "G190513-", - "T190514-", - "G190515-", - "A190516-", - "T190517-", - "A190518-", - "T190519-", - "A190520-", - "A190521-", - "C190522-", - "T190523-", - "A190524-", - "A190525-", - "T190526-", - "A190527-", - "C190528-", - "A190529-", - "G190530-", - "C190531-", - "A190532-", - "G190533-", - "A190534-", - "T190535-", - "A190536-", - "T190537-", - "A190538-", - "T190539-", - "T190540-", - "G190541-", - "C190542-", - "T190543-", - "G190544-", - "G190545-", - "A190546-", - "C190547-", - "A190548-", - "A190549-", - "T190550-", - "T190551-", - "A190552-", - "T190553-", - "C190554-", - "C190555-", - "A190556-", - "A190557-", - "T190558-", - "T190559-", - "A190560-", - "T190561-", - "G190562-", - "A190563-", - "C190564-", - "C190565-", - "T190566-", - "T190567-", - "T190568-", - "G190569-", - "A190570-", - "T190571-", - "G190572-", - "G190573-", - "A190574-", - "A190575-", - "A190576-", - "G190577-", - "G190578-", - "A190579-", - "T190580-", - "A190581-", - "T190582-", - "T190583-", - "T190584-", - "A190585-", - "T190586-", - "C190587-", - "C190588-", - "A190589-", - "T190590-", - "C190591-", - "T190592-", - "A190593-", - "T190594-", - "C190595-", - "T190596-", - "C190597-", - "G190598-", - "T190599-", - "T190600-", - "C190601-", - "A190602-", - "T190603-", - "G190604-", - "G190605-", - "T190606-", - "C190607-", - "G190608-", - "G190609-", - "T190610-", - "A190611-", - "A190612-", - "T190613-", - "A190614-", - "A190615-", - "A190616-", - "C190617-", - "T190618-", - "T190619-", - "T190620-", - "T190621-", - "C190622-", - "C190623-", - "T190624-", - "A190625-", - "G190626-", - "A190627-", - "T190628-", - "C190629-", - "T190630-", - "T190631-", - "T190632-", - "A190633-", - "T190634-", - "A190635-", - "A190636-", - "A190637-", - "A190638-", - "A190639-", - "T190640-", - "A190641-", - "T190642-", - "C190643-", - "T190644-", - "T190645-", - "T190646-", - "G190647-", - "A190648-", - "A190649-", - "G190650-", - "A190651-", - "A190652-", - "T190653-", - "T190654-", - "T190655-", - "T190656-", - "T190657-", - "C190658-", - "A190659-", - "G190660-", - "A190661-", - "C190662-", - "T190663-", - "A190664-", - "T190665-", - "T190666-", - "T190667-", - "C190668-", - "G190669-", - "A190670-", - "G190671-", - "T190672-", - "A190673-", - "T190674-", - "C190675-", - "T190676-", - "G190677-", - "T190678-", - "A190679-", - "A190680-", - "G190681-", - "T190682-", - "A190683-", - "G190684-", - "T190685-", - "C190686-", - "A190687-", - "A190688-", - "T190689-", - "A190690-", - "C190691-", - "G190692-", - "A190693-", - "G190694-", - "G190695-", - "A190696-", - "A190697-", - "T190698-", - "T190699-", - "A190700-", - "G190701-", - "A190702-", - "A190703-", - "T190704-", - "A190705-", - "T190706-", - "T190707-", - "A190708-", - "T190709-", - "T190710-", - "A190711-", - "T190712-", - "T190713-", - "C190714-", - "A190715-", - "T190716-", - "G190717-", - "T190718-", - "G190719-", - "A190720-", - "T190721-", - "T190722-", - "A190723-", - "T190724-", - "A190725-", - "C190726-", - "T190727-", - "A190728-", - "A190729-", - "C190730-", - "A190731-", - "A190732-", - "C190733-", - "C190734-", - "G190735-", - "T190736-", - "C190737-", - "C190738-", - "T190739-", - "A190740-", - "C190741-", - "A190742-", - "A190743-", - "T190744-", - "T190745-", - "A190746-", - "A190747-", - "A190748-", - "C190749-", - "A190750-", - "A190751-", - "C190752-", - "A190753-", - "T190754-", - "T190755-", - "A190756-", - "C190757-", - "T190758-", - "T190759-", - "T190760-", - "T190761-", - "A190762-", - "T190763-", - "A190764-", - "A190765-", - "C190766-", - "G190767-", - "G190768-", - "C190769-", - "G190770-", - "A190771-", - "C190772-", - "G190773-", - "A190774-", - "A190775-", - "T190776-", - "A190777-", - "T190778-", - "A190779-", - "C190780-", - "T190781-", - "G190782-", - "A190783-", - "A190784-", - "A190785-", - "T190786-", - "T190787-", - "G190788-", - "A190789-", - "T190790-", - "A190791-", - "G190792-", - "A190793-", - "T190794-", - "C190795-", - "G190796-", - "A190797-", - "A190798-", - "A190799-", - "A190800-", - "A190801-", - "A190802-", - "G190803-", - "C190804-", - "C190805-", - "A190806-", - "C190807-", - "T190808-", - "A190809-", - "A190810-", - "T190811-", - "A190812-", - "A190813-", - "A190814-", - "A190815-", - "A190816-", - "C190817-", - "A190818-", - "G190819-", - "T190820-", - "T190821-", - "G190822-", - "G190823-", - "T190824-", - "T190825-", - "A190826-", - "A190827-", - "T190828-", - "T190829-", - "A190830-", - "C190831-", - "T190832-", - "T190833-", - "C190834-", - "A190835-", - "G190836-", - "G190837-", - "C190838-", - "T190839-", - "T190840-", - "T190841-", - "A190842-", - "G190843-", - "A190844-", - "C190845-", - "T190846-", - "A190847-", - "C190848-", - "A190849-", - "A190850-", - "A190851-", - "A190852-", - "A190853-", - "T190854-", - "G190855-", - "G190856-", - "T190857-", - "T190858-", - "C190859-", - "G190860-", - "A190861-", - "T190862-", - "A190863-", - "G190864-", - "C190865-", - "G190866-", - "A190867-", - "A190868-", - "G190869-", - "A190870-", - "T190871-", - "T190872-", - "G190873-", - "T190874-", - "A190875-", - "T190876-", - "A190877-", - "A190878-", - "T190879-", - "T190880-", - "T190881-", - "A190882-", - "T190883-", - "C190884-", - "T190885-", - "C190886-", - "A190887-", - "G190888-", - "A190889-", - "T190890-", - "C190891-", - "T190892-", - "T190893-", - "T190894-", - "A190895-", - "G190896-", - "T190897-", - "T190898-", - "A190899-", - "G190900-", - "A190901-", - "A190902-", - "G190903-", - "A190904-", - "A190905-", - "T190906-", - "G190907-", - "G190908-", - "A190909-", - "A190910-", - "G190911-", - "A190912-", - "C190913-", - "A190914-", - "G190915-", - "T190916-", - "A190917-", - "A190918-", - "C190919-", - "A190920-", - "A190921-", - "A190922-", - "A190923-", - "A190924-", - "C190925-", - "A190926-", - "G190927-", - "T190928-", - "A190929-", - "A190930-", - "A190931-", - "A190932-", - "A190933-", - "A190934-", - "A190935-", - "C190936-", - "T190937-", - "T190938-", - "A190939-", - "G190940-", - "T190941-", - "A190942-", - "C190943-", - "T190944-", - "T190945-", - "A190946-", - "G190947-", - "A190948-", - "T190949-", - "A190950-", - "T190951-", - "C190952-", - "G190953-", - "A190954-", - "A190955-", - "A190956-", - "A190957-", - "A190958-", - "A190959-", - "T190960-", - "A190961-", - "T190962-", - "A190963-", - "T190964-", - "T190965-", - "T190966-", - "T190967-", - "T190968-", - "G190969-", - "T190970-", - "A190971-", - "G190972-", - "A190973-", - "C190974-", - "T190975-", - "C190976-", - "T190977-", - "T190978-", - "G190979-", - "A190980-", - "G190981-", - "A190982-", - "A190983-", - "T190984-", - "A190985-", - "G190986-", - "A190987-", - "A190988-", - "G190989-", - "G190990-", - "A190991-", - "A190992-", - "A190993-", - "A190994-", - "C190995-", - "A190996-", - "T190997-", - "G190998-", - "T190999-", - "A191000-", - "C191001-", - "A191002-", - "T191003-", - "A191004-", - "A191005-", - "T191006-", - "T191007-", - "A191008-", - "T191009-", - "A191010-", - "A191011-", - "A191012-", - "A191013-", - "A191014-", - "A191015-", - "T191016-", - "G191017-", - "A191018-", - "A191019-", - "A191020-", - "A191021-", - "T191022-", - "C191023-", - "A191024-", - "A191025-", - "T191026-", - "G191027-", - "G191028-", - "C191029-", - "G191030-", - "A191031-", - "A191032-", - "T191033-", - "A191034-", - "A191035-", - "G191036-", - "A191037-", - "C191038-", - "A191039-", - "G191040-", - "T191041-", - "G191042-", - "C191043-", - "G191044-", - "A191045-", - "T191046-", - "T191047-", - "C191048-", - "G191049-", - "C191050-", - "A191051-", - "C191052-", - "C191053-", - "A191054-", - "T191055-", - "G191056-", - "G191057-", - "A191058-", - "G191059-", - "T191060-", - "C191061-", - "G191062-", - "G191063-", - "T191064-", - "A191065-", - "G191066-", - "A191067-", - "T191068-", - "T191069-", - "T191070-", - "C191071-", - "A191072-", - "T191073-", - "G191074-", - "G191075-", - "C191076-", - "T191077-", - "G191078-", - "T191079-", - "C191080-", - "G191081-", - "A191082-", - "T191083-", - "G191084-", - "A191085-", - "G191086-", - "C191087-", - "A191088-", - "G191089-", - "T191090-", - "T191091-", - "T191092-", - "C191093-", - "A191094-", - "C191095-", - "G191096-", - "A191097-", - "C191098-", - "G191099-", - "A191100-", - "C191101-", - "C191102-", - "T191103-", - "C191104-", - "G191105-", - "A191106-", - "T191107-", - "C191108-", - "T191109-", - "T191110-", - "T191111-", - "G191112-", - "G191113-", - "T191114-", - "C191115-", - "A191116-", - "T191117-", - "T191118-", - "A191119-", - "T191120-", - "C191121-", - "T191122-", - "T191123-", - "T191124-", - "G191125-", - "G191126-", - "T191127-", - "A191128-", - "G191129-", - "A191130-", - "T191131-", - "G191132-", - "A191133-", - "T191134-", - "T191135-", - "A191136-", - "T191137-", - "A191138-", - "A191139-", - "A191140-", - "A191141-", - "A191142-", - "A191143-", - "C191144-", - "A191145-", - "T191146-", - "G191147-", - "G191148-", - "A191149-", - "T191150-", - "T191151-", - "A191152-", - "G191153-", - "G191154-", - "T191155-", - "G191156-", - "T191157-", - "T191158-", - "G191159-", - "A191160-", - "C191161-", - "T191162-", - "G191163-", - "T191164-", - "T191165-", - "A191166-", - "T191167-", - "G191168-", - "T191169-", - "T191170-", - "C191171-", - "T191172-", - "A191173-", - "G191174-", - "A191175-", - "A191176-", - "C191177-", - "C191178-", - "A191179-", - "G191180-", - "T191181-", - "T191182-", - "G191183-", - "T191184-", - "T191185-", - "G191186-", - "A191187-", - "C191188-", - "A191189-", - "G191190-", - "G191191-", - "A191192-", - "A191193-", - "A191194-", - "A191195-", - "T191196-", - "A191197-", - "T191198-", - "T191199-", - "T191200-", - "G191201-", - "A191202-", - "T191203-", - "A191204-", - "G191205-", - "A191206-", - "T191207-", - "T191208-", - "T191209-", - "C191210-", - "T191211-", - "C191212-", - "C191213-", - "T191214-", - "T191215-", - "G191216-", - "A191217-", - "A191218-", - "C191219-", - "C191220-", - "A191221-", - "A191222-", - "T191223-", - "T191224-", - "T191225-", - "G191226-", - "T191227-", - "G191228-", - "A191229-", - "T191230-", - "C191231-", - "C191232-", - "T191233-", - "G191234-", - "T191235-", - "A191236-", - "G191237-", - "A191238-", - "T191239-", - "G191240-", - "T191241-", - "T191242-", - "C191243-", - "T191244-", - "G191245-", - "T191246-", - "A191247-", - "T191248-", - "G191249-", - "A191250-", - "T191251-", - "T191252-", - "A191253-", - "T191254-", - "T191255-", - "T191256-", - "T191257-", - "A191258-", - "G191259-", - "G191260-", - "A191261-", - "T191262-", - "T191263-", - "C191264-", - "A191265-", - "T191266-", - "A191267-", - "G191268-", - "A191269-", - "G191270-", - "A191271-", - "T191272-", - "A191273-", - "A191274-", - "T191275-", - "A191276-", - "T191277-", - "T191278-", - "G191279-", - "A191280-", - "T191281-", - "C191282-", - "A191283-", - "G191284-", - "T191285-", - "A191286-", - "T191287-", - "A191288-", - "T191289-", - "A191290-", - "G191291-", - "T191292-", - "A191293-", - "G191294-", - "A191295-", - "T191296-", - "A191297-", - "G191298-", - "A191299-", - "C191300-", - "T191301-", - "G191302-", - "T191303-", - "T191304-", - "T191305-", - "G191306-", - "C191307-", - "A191308-", - "T191309-", - "A191310-", - "T191311-", - "A191312-", - "T191313-", - "T191314-", - "A191315-", - "C191316-", - "A191317-", - "T191318-", - "A191319-", - "T191320-", - "A191321-", - "A191322-", - "A191323-", - "G191324-", - "A191325-", - "T191326-", - "A191327-", - "T191328-", - "T191329-", - "A191330-", - "T191331-", - "A191332-", - "T191333-", - "C191334-", - "T191335-", - "G191336-", - "C191337-", - "A191338-", - "T191339-", - "T191340-", - "A191341-", - "G191342-", - "T191343-", - "G191344-", - "T191345-", - "C191346-", - "A191347-", - "A191348-", - "A191349-", - "G191350-", - "A191351-", - "A191352-", - "T191353-", - "T191354-", - "A191355-", - "T191356-", - "A191357-", - "T191358-", - "G191359-", - "G191360-", - "A191361-", - "A191362-", - "G191363-", - "A191364-", - "T191365-", - "A191366-", - "T191367-", - "T191368-", - "T191369-", - "T191370-", - "C191371-", - "T191372-", - "C191373-", - "T191374-", - "A191375-", - "T191376-", - "A191377-", - "A191378-", - "T191379-", - "T191380-", - "A191381-", - "T191382-", - "T191383-", - "A191384-", - "A191385-", - "G191386-", - "A191387-", - "A191388-", - "T191389-", - "T191390-", - "G191391-", - "T191392-", - "A191393-", - "A191394-", - "T191395-", - "T191396-", - "C191397-", - "T191398-", - "G191399-", - "T191400-", - "G191401-", - "C191402-", - "A191403-", - "A191404-", - "G191405-", - "A191406-", - "T191407-", - "C191408-", - "T191409-", - "C191410-", - "T191411-", - "T191412-", - "A191413-", - "C191414-", - "T191415-", - "T191416-", - "T191417-", - "A191418-", - "C191419-", - "T191420-", - "A191421-", - "T191422-", - "C191423-", - "T191424-", - "A191425-", - "T191426-", - "C191427-", - "T191428-", - "A191429-", - "A191430-", - "T191431-", - "G191432-", - "C191433-", - "A191434-", - "T191435-", - "A191436-", - "T191437-", - "G191438-", - "T191439-", - "A191440-", - "G191441-", - "A191442-", - "A191443-", - "A191444-", - "T191445-", - "A191446-", - "G191447-", - "A191448-", - "C191449-", - "A191450-", - "T191451-", - "T191452-", - "G191453-", - "T191454-", - "T191455-", - "G191456-", - "A191457-", - "T191458-", - "C191459-", - "T191460-", - "T191461-", - "A191462-", - "T191463-", - "G191464-", - "G191465-", - "T191466-", - "A191467-", - "G191468-", - "A191469-", - "T191470-", - "C191471-", - "A191472-", - "T191473-", - "G191474-", - "G191475-", - "G191476-", - "G191477-", - "C191478-", - "T191479-", - "G191480-", - "T191481-", - "A191482-", - "A191483-", - "T191484-", - "A191485-", - "T191486-", - "A191487-", - "T191488-", - "A191489-", - "A191490-", - "A191491-", - "A191492-", - "T191493-", - "A191494-", - "G191495-", - "A191496-", - "A191497-", - "T191498-", - "G191499-", - "C191500-", - "T191501-", - "T191502-", - "G191503-", - "A191504-", - "A191505-", - "T191506-", - "G191507-", - "C191508-", - "C191509-", - "T191510-", - "A191511-", - "T191512-", - "T191513-", - "T191514-", - "T191515-", - "A191516-", - "G191517-", - "G191518-", - "G191519-", - "G191520-", - "A191521-", - "A191522-", - "T191523-", - "A191524-", - "T191525-", - "G191526-", - "T191527-", - "A191528-", - "A191529-", - "A191530-", - "A191531-", - "A191532-", - "G191533-", - "G191534-", - "A191535-", - "A191536-", - "A191537-", - "G191538-", - "T191539-", - "A191540-", - "G191541-", - "T191542-", - "G191543-", - "T191544-", - "T191545-", - "G191546-", - "T191547-", - "T191548-", - "G191549-", - "A191550-", - "G191551-", - "T191552-", - "T191553-", - "T191554-", - "A191555-", - "T191556-", - "T191557-", - "T191558-", - "T191559-", - "G191560-", - "A191561-", - "A191562-", - "T191563-", - "T191564-", - "G191565-", - "T191566-", - "G191567-", - "G191568-", - "T191569-", - "A191570-", - "T191571-", - "C191572-", - "C191573-", - "C191574-", - "A191575-", - "G191576-", - "A191577-", - "T191578-", - "G191579-", - "A191580-", - "A191581-", - "A191582-", - "A191583-", - "T191584-", - "G191585-", - "A191586-", - "T191587-", - "G191588-", - "T191589-", - "T191590-", - "A191591-", - "A191592-", - "A191593-", - "T191594-", - "T191595-", - "A191596-", - "G191597-", - "A191598-", - "T191599-", - "C191600-", - "T191601-", - "A191602-", - "T191603-", - "A191604-", - "T191605-", - "A191606-", - "A191607-", - "A191608-", - "A191609-", - "T191610-", - "A191611-", - "A191612-", - "T191613-", - "T191614-", - "C191615-", - "A191616-", - "G191617-", - "T191618-", - "A191619-", - "T191620-", - "A191621-", - "C191622-", - "T191623-", - "A191624-", - "G191625-", - "G191626-", - "G191627-", - "G191628-", - "A191629-", - "T191630-", - "T191631-", - "C191632-", - "C191633-", - "T191634-", - "T191635-", - "G191636-", - "T191637-", - "A191638-", - "G191639-", - "A191640-", - "T191641-", - "G191642-", - "A191643-", - "A191644-", - "C191645-", - "C191646-", - "C191647-", - "A191648-", - "C191649-", - "A191650-", - "G191651-", - "T191652-", - "A191653-", - "T191654-", - "T191655-", - "A191656-", - "G191657-", - "A191658-", - "A191659-", - "A191660-", - "T191661-", - "T191662-", - "T191663-", - "A191664-", - "T191665-", - "A191666-", - "A191667-", - "G191668-", - "C191669-", - "T191670-", - "T191671-", - "T191672-", - "G191673-", - "T191674-", - "A191675-", - "T191676-", - "C191677-", - "C191678-", - "C191679-", - "A191680-", - "T191681-", - "A191682-", - "T191683-", - "A191684-", - "T191685-", - "T191686-", - "G191687-", - "A191688-", - "A191689-", - "G191690-", - "A191691-", - "T191692-", - "A191693-", - "T191694-", - "C191695-", - "A191696-", - "A191697-", - "T191698-", - "C191699-", - "A191700-", - "A191701-", - "C191702-", - "T191703-", - "A191704-", - "G191705-", - "A191706-", - "T191707-", - "G191708-", - "C191709-", - "T191710-", - "G191711-", - "G191712-", - "T191713-", - "G191714-", - "G191715-", - "A191716-", - "A191717-", - "G191718-", - "G191719-", - "A191720-", - "C191721-", - "C191722-", - "T191723-", - "T191724-", - "G191725-", - "C191726-", - "T191727-", - "T191728-", - "T191729-", - "A191730-", - "T191731-", - "C191732-", - "G191733-", - "C191734-", - "G191735-", - "C191736-", - "T191737-", - "A191738-", - "T191739-", - "C191740-", - "T191741-", - "A191742-", - "T191743-", - "G191744-", - "C191745-", - "A191746-", - "G191747-", - "G191748-", - "T191749-", - "T191750-", - "A191751-", - "T191752-", - "A191753-", - "T191754-", - "A191755-", - "G191756-", - "A191757-", - "T191758-", - "T191759-", - "T191760-", - "A191761-", - "G191762-", - "T191763-", - "A191764-", - "T191765-", - "C191766-", - "A191767-", - "T191768-", - "G191769-", - "G191770-", - "C191771-", - "T191772-", - "A191773-", - "T191774-", - "T191775-", - "A191776-", - "G191777-", - "A191778-", - "A191779-", - "A191780-", - "A191781-", - "T191782-", - "G191783-", - "G191784-", - "A191785-", - "G191786-", - "C191787-", - "A191788-", - "A191789-", - "A191790-", - "T191791-", - "G191792-", - "T191793-", - "C191794-", - "A191795-", - "A191796-", - "C191797-", - "G191798-", - "C191799-", - "A191800-", - "G191801-", - "T191802-", - "A191803-", - "A191804-", - "T191805-", - "G191806-", - "A191807-", - "G191808-", - "T191809-", - "A191810-", - "A191811-", - "T191812-", - "G191813-", - "G191814-", - "A191815-", - "T191816-", - "A191817-", - "T191818-", - "A191819-", - "C191820-", - "A191821-", - "T191822-", - "G191823-", - "T191824-", - "C191825-", - "T191826-", - "T191827-", - "G191828-", - "A191829-", - "C191830-", - "G191831-", - "T191832-", - "G191833-", - "G191834-", - "C191835-", - "C191836-", - "G191837-", - "T191838-", - "G191839-", - "G191840-", - "A191841-", - "T191842-", - "A191843-", - "G191844-", - "G191845-", - "G191846-", - "G191847-", - "A191848-", - "T191849-", - "C191850-", - "T191851-", - "G191852-", - "T191853-", - "C191854-", - "A191855-", - "T191856-", - "C191857-", - "G191858-", - "C191859-", - "C191860-", - "C191861-", - "G191862-", - "T191863-", - "A191864-", - "G191865-", - "G191866-", - "G191867-", - "A191868-", - "A191869-", - "G191870-", - "C191871-", - "A191872-", - "C191873-", - "A191874-", - "T191875-", - "C191876-", - "T191877-", - "T191878-", - "A191879-", - "A191880-", - "A191881-", - "A191882-", - "T191883-", - "A191884-", - "T191885-", - "T191886-", - "A191887-", - "G191888-", - "A191889-", - "A191890-", - "A191891-", - "T191892-", - "A191893-", - "T191894-", - "T191895-", - "G191896-", - "C191897-", - "T191898-", - "T191899-", - "A191900-", - "G191901-", - "A191902-", - "G191903-", - "A191904-", - "A191905-", - "C191906-", - "C191907-", - "A191908-", - "T191909-", - "T191910-", - "G191911-", - "T191912-", - "C191913-", - "T191914-", - "A191915-", - "T191916-", - "T191917-", - "G191918-", - "A191919-", - "C191920-", - "T191921-", - "G191922-", - "T191923-", - "A191924-", - "T191925-", - "A191926-", - "A191927-", - "A191928-", - "A191929-", - "T191930-", - "T191931-", - "A191932-", - "G191933-", - "C191934-", - "T191935-", - "A191936-", - "T191937-", - "A191938-", - "C191939-", - "T191940-", - "T191941-", - "A191942-", - "A191943-", - "T191944-", - "A191945-", - "A191946-", - "T191947-", - "A191948-", - "C191949-", - "A191950-", - "A191951-", - "T191952-", - "T191953-", - "G191954-", - "A191955-", - "A191956-", - "A191957-", - "A191958-", - "C191959-", - "C191960-", - "A191961-", - "T191962-", - "G191963-", - "A191964-", - "T191965-", - "G191966-", - "T191967-", - "G191968-", - "A191969-", - "T191970-", - "A191971-", - "A191972-", - "A191973-", - "G191974-", - "C191975-", - "T191976-", - "C191977-", - "T191978-", - "G191979-", - "T191980-", - "A191981-", - "T191982-", - "C191983-", - "A191984-", - "A191985-", - "G191986-", - "T191987-", - "A191988-", - "T191989-", - "T191990-", - "T191991-", - "T191992-", - "A191993-", - "T191994-", - "G191995-", - "A191996-", - "T191997-", - "G191998-", - "G191999-", - "T192000-", - "A192001-", - "G192002-", - "A192003-", - "T192004-", - "T192005-", - "A192006-", - "T192007-", - "T192008-", - "C192009-", - "A192010-", - "C192011-", - "T192012-", - "T192013-", - "T192014-", - "G192015-", - "T192016-", - "A192017-", - "A192018-", - "T192019-", - "G192020-", - "T192021-", - "G192022-", - "T192023-", - "A192024-", - "T192025-", - "G192026-", - "C192027-", - "A192028-", - "T192029-", - "C192030-", - "A192031-", - "T192032-", - "C192033-", - "A192034-", - "C192035-", - "T192036-", - "C192037-", - "T192038-", - "T192039-", - "T192040-", - "G192041-", - "A192042-", - "T192043-", - "T192044-", - "A192045-", - "T192046-", - "A192047-", - "T192048-", - "A192049-", - "A192050-", - "T192051-", - "T192052-", - "G192053-", - "A192054-", - "T192055-", - "T192056-", - "G192057-", - "T192058-", - "A192059-", - "A192060-", - "A192061-", - "C192062-", - "A192063-", - "A192064-", - "G192065-", - "A192066-", - "A192067-", - "T192068-", - "T192069-", - "G192070-", - "G192071-", - "A192072-", - "G192073-", - "T192074-", - "A192075-", - "C192076-", - "A192077-", - "T192078-", - "T192079-", - "A192080-", - "G192081-", - "G192082-", - "C192083-", - "A192084-", - "G192085-", - "A192086-", - "T192087-", - "G192088-", - "A192089-", - "A192090-", - "A192091-", - "A192092-", - "T192093-", - "T192094-", - "C192095-", - "A192096-", - "T192097-", - "A192098-", - "A192099-", - "T192100-", - "A192101-", - "C192102-", - "A192103-", - "A192104-", - "C192105-", - "C192106-", - "A192107-", - "T192108-", - "G192109-", - "T192110-", - "A192111-", - "T192112-", - "G192113-", - "A192114-", - "G192115-", - "T192116-", - "T192117-", - "A192118-", - "A192119-", - "T192120-", - "C192121-", - "T192122-", - "A192123-", - "T192124-", - "A192125-", - "A192126-", - "T192127-", - "A192128-", - "G192129-", - "A192130-", - "G192131-", - "A192132-", - "C192133-", - "A192134-", - "A192135-", - "A192136-", - "A192137-", - "A192138-", - "C192139-", - "A192140-", - "A192141-", - "G192142-", - "C192143-", - "A192144-", - "T192145-", - "G192146-", - "C192147-", - "T192148-", - "T192149-", - "C192150-", - "C192151-", - "C192152-", - "A192153-", - "T192154-", - "A192155-", - "T192156-", - "T192157-", - "C192158-", - "T192159-", - "A192160-", - "C192161-", - "A192162-", - "T192163-", - "A192164-", - "G192165-", - "G192166-", - "T192167-", - "A192168-", - "T192169-", - "T192170-", - "C192171-", - "T192172-", - "A192173-", - "A192174-", - "A192175-", - "C192176-", - "A192177-", - "T192178-", - "C192179-", - "C192180-", - "A192181-", - "G192182-", - "T192183-", - "T192184-", - "T192185-", - "T192186-", - "G192187-", - "A192188-", - "C192189-", - "A192190-", - "C192191-", - "A192192-", - "G192193-", - "T192194-", - "G192195-", - "T192196-", - "A192197-", - "T192198-", - "C192199-", - "A192200-", - "C192201-", - "T192202-", - "A192203-", - "A192204-", - "A192205-", - "G192206-", - "G192207-", - "A192208-", - "T192209-", - "T192210-", - "C192211-", - "A192212-", - "A192213-", - "G192214-", - "A192215-", - "T192216-", - "T192217-", - "T192218-", - "A192219-", - "C192220-", - "A192221-", - "C192222-", - "A192223-", - "G192224-", - "A192225-", - "A192226-", - "G192227-", - "T192228-", - "A192229-", - "A192230-", - "C192231-", - "C192232-", - "G192233-", - "A192234-", - "G192235-", - "C192236-", - "A192237-", - "G192238-", - "G192239-", - "T192240-", - "C192241-", - "A192242-", - "C192243-", - "T192244-", - "A192245-", - "A192246-", - "A192247-", - "G192248-", - "C192249-", - "T192250-", - "C192251-", - "T192252-", - "A192253-", - "A192254-", - "A192255-", - "C192256-", - "A192257-", - "G192258-", - "A192259-", - "C192260-", - "G192261-", - "T192262-", - "G192263-", - "C192264-", - "T192265-", - "C192266-", - "T192267-", - "A192268-", - "A192269-", - "T192270-", - "A192271-", - "G192272-", - "A192273-", - "T192274-", - "G192275-", - "A192276-", - "G192277-", - "A192278-", - "T192279-", - "A192280-", - "A192281-", - "T192282-", - "A192283-", - "A192284-", - "A192285-", - "C192286-", - "A192287-", - "A192288-", - "T192289-", - "G192290-", - "T192291-", - "A192292-", - "T192293-", - "C192294-", - "A192295-", - "A192296-", - "C192297-", - "T192298-", - "G192299-", - "A192300-", - "T192301-", - "G192302-", - "A192303-", - "C192304-", - "A192305-", - "A192306-", - "T192307-", - "C192308-", - "T192309-", - "C192310-", - "C192311-", - "T192312-", - "A192313-", - "T192314-", - "C192315-", - "A192316-", - "A192317-", - "A192318-", - "A192319-", - "C192320-", - "T192321-", - "T192322-", - "C192323-", - "C192324-", - "A192325-", - "T192326-", - "T192327-", - "A192328-", - "G192329-", - "A192330-", - "A192331-", - "A192332-", - "T192333-", - "T192334-", - "A192335-", - "G192336-", - "G192337-", - "G192338-", - "A192339-", - "T192340-", - "C192341-", - "T192342-", - "A192343-", - "A192344-", - "T192345-", - "T192346-", - "G192347-", - "T192348-", - "T192349-", - "T192350-", - "C192351-", - "A192352-", - "C192353-", - "A192354-", - "A192355-", - "G192356-", - "C192357-", - "T192358-", - "G192359-", - "T192360-", - "C192361-", - "A192362-", - "T192363-", - "A192364-", - "T192365-", - "A192366-", - "G192367-", - "A192368-", - "G192369-", - "T192370-", - "T192371-", - "C192372-", - "T192373-", - "A192374-", - "T192375-", - "C192376-", - "C192377-", - "A192378-", - "C192379-", - "C192380-", - "C192381-", - "A192382-", - "C192383-", - "C192384-", - "T192385-", - "T192386-", - "T192387-", - "C192388-", - "T192389-", - "T192390-", - "G192391-", - "A192392-", - "A192393-", - "A192394-", - "T192395-", - "G192396-", - "A192397-", - "G192398-", - "T192399-", - "T192400-", - "A192401-", - "A192402-", - "T192403-", - "A192404-", - "G192405-", - "T192406-", - "C192407-", - "A192408-", - "T192409-", - "A192410-", - "A192411-", - "G192412-", - "T192413-", - "T192414-", - "A192415-", - "G192416-", - "T192417-", - "T192418-", - "A192419-", - "A192420-", - "G192421-", - "T192422-", - "C192423-", - "A192424-", - "T192425-", - "A192426-", - "A192427-", - "G192428-", - "T192429-", - "T192430-", - "A192431-", - "G192432-", - "T192433-", - "T192434-", - "A192435-", - "A192436-", - "G192437-", - "T192438-", - "C192439-", - "A192440-", - "T192441-", - "A192442-", - "A192443-", - "G192444-", - "T192445-", - "T192446-", - "A192447-", - "G192448-", - "T192449-", - "T192450-", - "A192451-", - "A196604-" - ], - "NBT03_gp174": [ - "M1-", - "D2-", - "S3-", - "R4-", - "I5-", - "A6-", - "I7-", - "Y8-", - "V9-", - "L10-", - "V11-", - "S12-", - "A13-", - "S14-", - "L15-", - "L16-", - "Y17-", - "L18-", - "V19-", - "N20-", - "C21-", - "H22-", - "K23-", - "L24-", - "V25-", - "H26-", - "Y27-", - "F28-", - "N29-", - "L30-", - "K31-", - "I32-", - "N33-", - "G34-", - "S35-", - "D36-", - "I37-", - "T38-", - "N39-", - "T40-", - "A41-", - "D42-", - "I43-", - "L44-", - "L45-", - "D46-", - "N47-", - "Y48-", - "P49-", - "I50-", - "M51-", - "T52-", - "F53-", - "D54-", - "G55-", - "K56-", - "D57-", - "I58-", - "Y59-", - "P60-", - "S61-", - "I62-", - "S63-", - "F64-", - "M65-", - "V66-", - "G67-", - "N68-", - "K69-", - "L70-", - "F71-", - "L72-", - "D73-", - "L74-", - "Y75-", - "K76-", - "N77-", - "I78-", - "F79-", - "E80-", - "E81-", - "F82-", - "F83-", - "R84-", - "L85-", - "F86-", - "R87-", - "V88-", - "S89-", - "V90-", - "S91-", - "S92-", - "Q93-", - "Y94-", - "E95-", - "E96-", - "L97-", - "E98-", - "Y99-", - "Y100-", - "Y101-", - "S102-", - "C103-", - "D104-", - "Y105-", - "T106-", - "N107-", - "N108-", - "R109-", - "P110-", - "T111-", - "I112-", - "K113-", - "Q114-", - "H115-", - "Y116-", - "F117-", - "Y118-", - "N119-", - "G120-", - "D121-", - "E122-", - "Y123-", - "T124-", - "E125-", - "I126-", - "D127-", - "R128-", - "S129-", - "K130-", - "K131-", - "A132-", - "T133-", - "N134-", - "K135-", - "N136-", - "S137-", - "W138-", - "L139-", - "I140-", - "T141-", - "S142-", - "G143-", - "F144-", - "R145-", - "L146-", - "Q147-", - "K148-", - "W149-", - "F150-", - "D151-", - "S152-", - "E153-", - "D154-", - "C155-", - "I156-", - "I157-", - "Y158-", - "L159-", - "R160-", - "S161-", - "L162-", - "V163-", - "R164-", - "R165-", - "M166-", - "E167-", - "D168-", - "S169-", - "N170-", - "K171-", - "N172-", - "S173-", - "K174-", - "K175-", - "T176-", - "*177-" - ], - "NBT03_gp175": [ - "M1-", - "E2-", - "S3-", - "V4-", - "D5-", - "F6-", - "M7-", - "A8-", - "V9-", - "D10-", - "E11-", - "Q12-", - "F13-", - "H14-", - "D15-", - "D16-", - "L17-", - "D18-", - "L19-", - "W20-", - "S21-", - "L22-", - "S23-", - "L24-", - "V25-", - "D26-", - "D27-", - "Y28-", - "K29-", - "K30-", - "H31-", - "G32-", - "L33-", - "G34-", - "V35-", - "D36-", - "C37-", - "Y38-", - "V39-", - "L40-", - "E41-", - "P42-", - "V43-", - "V44-", - "D45-", - "R46-", - "K47-", - "I48-", - "F49-", - "D50-", - "R51-", - "F52-", - "L53-", - "L54-", - "E55-", - "P56-", - "I57-", - "C58-", - "D59-", - "P60-", - "V61-", - "D62-", - "V63-", - "L64-", - "Y65-", - "D66-", - "Y67-", - "F68-", - "R69-", - "I70-", - "H71-", - "R72-", - "D73-", - "N74-", - "I75-", - "D76-", - "Q77-", - "Y78-", - "I79-", - "V80-", - "D81-", - "R82-", - "L83-", - "F84-", - "A85-", - "Y86-", - "I87-", - "T88-", - "Y89-", - "K90-", - "D91-", - "I92-", - "I93-", - "S94-", - "A95-", - "L96-", - "V97-", - "S98-", - "K99-", - "N100-", - "Y101-", - "M102-", - "E103-", - "D104-", - "I105-", - "F106-", - "S107-", - "I108-", - "I109-", - "I110-", - "K111-", - "N112-", - "C113-", - "N114-", - "S115-", - "V116-", - "Q117-", - "D118-", - "L119-", - "L120-", - "L121-", - "Y122-", - "Y123-", - "L124-", - "S125-", - "N126-", - "A127-", - "Y128-", - "V129-", - "E130-", - "I131-", - "D132-", - "I133-", - "V134-", - "D135-", - "L136-", - "M137-", - "V138-", - "D139-", - "H140-", - "G141-", - "A142-", - "V143-", - "I144-", - "Y145-", - "K146-", - "I147-", - "E148-", - "C149-", - "L150-", - "N151-", - "A152-", - "Y153-", - "F154-", - "R155-", - "G156-", - "I157-", - "C158-", - "K159-", - "K160-", - "E161-", - "S162-", - "S163-", - "V164-", - "V165-", - "E166-", - "F167-", - "I168-", - "L169-", - "N170-", - "C171-", - "G172-", - "I173-", - "P174-", - "D175-", - "E176-", - "N177-", - "D178-", - "V179-", - "K180-", - "L181-", - "D182-", - "L183-", - "Y184-", - "K185-", - "I186-", - "I187-", - "Q188-", - "Y189-", - "T190-", - "R191-", - "G192-", - "F193-", - "L194-", - "V195-", - "D196-", - "E197-", - "P198-", - "T199-", - "V200-", - "L201-", - "E202-", - "I203-", - "Y204-", - "K205-", - "L206-", - "C207-", - "I208-", - "P209-", - "Y210-", - "I211-", - "E212-", - "D213-", - "I214-", - "N215-", - "Q216-", - "L217-", - "D218-", - "A219-", - "G220-", - "G221-", - "R222-", - "T223-", - "L224-", - "L225-", - "Y226-", - "R227-", - "A228-", - "I229-", - "Y230-", - "A231-", - "G232-", - "Y233-", - "I234-", - "D235-", - "L236-", - "V237-", - "S238-", - "W239-", - "L240-", - "L241-", - "E242-", - "N243-", - "G244-", - "A245-", - "N246-", - "V247-", - "N248-", - "A249-", - "V250-", - "M251-", - "S252-", - "N253-", - "G254-", - "Y255-", - "T256-", - "C257-", - "L258-", - "D259-", - "V260-", - "A261-", - "V262-", - "D263-", - "R264-", - "G265-", - "S266-", - "V267-", - "I268-", - "A269-", - "R270-", - "R271-", - "E272-", - "A273-", - "H274-", - "L275-", - "K276-", - "I277-", - "L278-", - "E279-", - "I280-", - "L281-", - "L282-", - "R283-", - "E284-", - "P285-", - "L286-", - "S287-", - "I288-", - "D289-", - "C290-", - "I291-", - "K292-", - "L293-", - "A294-", - "I295-", - "L296-", - "N297-", - "N298-", - "T299-", - "I300-", - "E301-", - "N302-", - "H303-", - "D304-", - "V305-", - "I306-", - "K307-", - "L308-", - "C309-", - "I310-", - "K311-", - "Y312-", - "F313-", - "M314-", - "M315-", - "V316-", - "D317-", - "Y318-", - "S319-", - "L320-", - "C321-", - "N322-", - "V323-", - "Y324-", - "A325-", - "S326-", - "S327-", - "L328-", - "F329-", - "D330-", - "Y331-", - "I332-", - "I333-", - "D334-", - "C335-", - "K336-", - "Q337-", - "E338-", - "L339-", - "E340-", - "Y341-", - "I342-", - "R343-", - "Q344-", - "M345-", - "K346-", - "I347-", - "H348-", - "N349-", - "T350-", - "T351-", - "M352-", - "Y353-", - "E354-", - "L355-", - "I356-", - "Y357-", - "N358-", - "R359-", - "D360-", - "K361-", - "N362-", - "K363-", - "H364-", - "A365-", - "S366-", - "H367-", - "I368-", - "L369-", - "H370-", - "R371-", - "Y372-", - "S373-", - "K374-", - "H375-", - "P376-", - "V377-", - "L378-", - "T379-", - "Q380-", - "C381-", - "I382-", - "T383-", - "K384-", - "G385-", - "F386-", - "K387-", - "I388-", - "Y389-", - "T390-", - "E391-", - "V392-", - "T393-", - "E394-", - "Q395-", - "V396-", - "T397-", - "K398-", - "A399-", - "L400-", - "N401-", - "R402-", - "R403-", - "A404-", - "L405-", - "I406-", - "D407-", - "E408-", - "I409-", - "I410-", - "N411-", - "N412-", - "V413-", - "S414-", - "T415-", - "D416-", - "D417-", - "N418-", - "L419-", - "L420-", - "S421-", - "K422-", - "L423-", - "P424-", - "L425-", - "E426-", - "I427-", - "R428-", - "D429-", - "L430-", - "I431-", - "V432-", - "S433-", - "Q434-", - "A435-", - "V436-", - "I437-", - "*438-" - ], - "OPG005": [ - "M1-", - "A2-", - "S3-", - "P4-", - "C5-", - "A6-", - "Q7-", - "F8-", - "S9-", - "P10-", - "C11-", - "H12-", - "C13-", - "H14-", - "A15-", - "T16-", - "K17-", - "D18-", - "S19-", - "L20-", - "N21-", - "T22-", - "V23-", - "T24-", - "D25-", - "V26-", - "R27-", - "H28-", - "C29-", - "L30-", - "T31-", - "E32-", - "Y33-", - "I34-", - "L35-", - "W36-", - "V37-", - "S38-", - "H39-", - "R40-", - "W41-", - "T42-", - "H43-", - "R44-", - "E45-", - "S46-", - "A47-", - "G48-", - "P49-", - "L50-", - "Y51-", - "R52-", - "L53-", - "L54-", - "I55-", - "S56-", - "F57-", - "R58-", - "I59-", - "D60-", - "A61-", - "M62-", - "E63-", - "L64-", - "F65-", - "G66-", - "S67-", - "E68-", - "L69-", - "K70-", - "E71-", - "F72-", - "S73-", - "N74-", - "S75-", - "L76-", - "P77-", - "W78-", - "D79-", - "N80-", - "I81-", - "D82-", - "N83-", - "C84-", - "V85-", - "E86-", - "I87-", - "I88-", - "K89-", - "C90-", - "F91-", - "I92-", - "R93-", - "N94-", - "D95-", - "S96-", - "M97-", - "K98-", - "T99-", - "A100-", - "K101-", - "E102-", - "L103-", - "C104-", - "A105-", - "I106-", - "I107-", - "G108-", - "L109-", - "C110-", - "T111-", - "Q112-", - "S113-", - "A114-", - "I115-", - "V116-", - "T117-", - "G118-", - "R119-", - "V120-", - "F121-", - "N122-", - "D123-", - "K124-", - "Y125-", - "I126-", - "D127-", - "I128-", - "L129-", - "L130-", - "M131-", - "L132-", - "R133-", - "K134-", - "I135-", - "L136-", - "N137-", - "E138-", - "N139-", - "D140-", - "Y141-", - "L142-", - "T143-", - "L144-", - "L145-", - "D146-", - "H147-", - "I148-", - "L149-", - "T150-", - "A151-", - "K152-", - "Y153-", - "*154-" - ], - "OPG188": [ - "S269L" - ], - "OPG210": [ - "S1406-", - "A1407-", - "M1408-", - "T1409-", - "I1410-", - "K1411-", - "V1412-", - "L1413-", - "P1414-", - "C1415-", - "T1416-", - "V1417-", - "R1418-", - "N1419-", - "K1420-", - "N1421-", - "I1422-", - "D1423-", - "F1424-", - "G1425-", - "Y1426-", - "N1427-", - "Y1428-", - "G1429-", - "D1430-", - "I1431-", - "I1432-", - "S1433-", - "N1434-", - "M1435-", - "V1436-", - "Y1437-", - "L1438-", - "Q1439-", - "S1440-", - "T1441-", - "S1442-", - "Q1443-", - "D1444-", - "Y1445-", - "G1446-", - "D1447-", - "G1448-", - "T1449-", - "K1450-", - "Y1451-", - "T1452-", - "F1453-", - "K1454-", - "S1455-", - "V1456-", - "T1457-", - "R1458-", - "S1459-", - "D1460-", - "H1461-", - "E1462-", - "C1463-", - "E1464-", - "S1465-", - "S1466-", - "L1467-", - "D1468-", - "L1469-", - "T1470-", - "S1471-", - "K1472-", - "E1473-", - "V1474-", - "T1475-", - "V1476-", - "T1477-", - "C1478-", - "P1479-", - "A1480-", - "F1481-", - "S1482-", - "I1483-", - "P1484-", - "R1485-", - "N1486-", - "I1487-", - "S1488-", - "T1489-", - "Y1490-", - "E1491-", - "G1492-", - "L1493-", - "C1494-", - "F1495-", - "S1496-", - "V1497-", - "T1498-", - "T1499-", - "S1500-", - "K1501-", - "D1502-", - "H1503-", - "C1504-", - "A1505-", - "T1506-", - "G1507-", - "I1508-", - "G1509-", - "W1510-", - "L1511-", - "K1512-", - "S1513-", - "S1514-", - "G1515-", - "Y1516-", - "G1517-", - "K1518-", - "E1519-", - "D1520-", - "A1521-", - "D1522-", - "K1523-", - "P1524-", - "R1525-", - "A1526-", - "C1527-", - "F1528-", - "H1529-", - "H1530-", - "W1531-", - "N1532-", - "Y1533-", - "Y1534-", - "T1535-", - "L1536-", - "S1537-", - "L1538-", - "D1539-", - "Y1540-", - "Y1541-", - "C1542-", - "S1543-", - "Y1544-", - "E1545-", - "D1546-", - "I1547-", - "W1548-", - "R1549-", - "S1550-", - "T1551-", - "W1552-", - "P1553-", - "D1554-", - "Y1555-", - "D1556-", - "P1557-", - "C1558-", - "K1559-", - "S1560-", - "Y1561-", - "I1562-", - "H1563-", - "I1564-", - "E1565-", - "Y1566-", - "R1567-", - "D1568-", - "T1569-", - "W1570-", - "I1571-", - "E1572-", - "S1573-", - "N1574-", - "V1575-", - "L1576-", - "Q1577-", - "Q1578-", - "P1579-", - "P1580-", - "Y1581-", - "T1582-", - "F1583-", - "E1584-", - "F1585-", - "I1586-", - "H1587-", - "D1588-", - "N1589-", - "S1590-", - "N1591-", - "E1592-", - "Y1593-", - "V1594-", - "D1595-", - "K1596-", - "E1597-", - "I1598-", - "S1599-", - "N1600-", - "K1601-", - "L1602-", - "N1603-", - "D1604-", - "L1605-", - "Y1606-", - "N1607-", - "E1608-", - "Y1609-", - "K1610-", - "K1611-", - "I1612-", - "M1613-", - "E1614-", - "Y1615-", - "S1616-", - "D1617-", - "G1618-", - "S1619-", - "L1620-", - "P1621-", - "A1622-", - "S1623-", - "I1624-", - "N1625-", - "R1626-", - "L1627-", - "A1628-", - "K1629-", - "A1630-", - "L1631-", - "T1632-", - "S1633-", - "E1634-", - "G1635-", - "R1636-", - "E1637-", - "I1638-", - "A1639-", - "S1640-", - "V1641-", - "N1642-", - "I1643-", - "D1644-", - "G1645-", - "N1646-", - "L1647-", - "L1648-", - "D1649-", - "I1650-", - "A1651-", - "Y1652-", - "Q1653-", - "A1654-", - "D1655-", - "K1656-", - "E1657-", - "K1658-", - "M1659-", - "A1660-", - "D1661-", - "I1662-", - "Q1663-", - "T1664-", - "R1665-", - "I1666-", - "N1667-", - "D1668-", - "I1669-", - "I1670-", - "R1671-", - "D1672-", - "L1673-", - "F1674-", - "I1675-", - "H1676-", - "T1677-", - "L1678-", - "S1679-", - "D1680-", - "K1681-", - "D1682-", - "I1683-", - "K1684-", - "D1685-", - "I1686-", - "I1687-", - "E1688-", - "S1689-", - "E1690-", - "E1691-", - "G1692-", - "K1693-", - "R1694-", - "C1695-", - "C1696-", - "I1697-", - "I1698-", - "D1699-", - "V1700-", - "K1701-", - "N1702-", - "N1703-", - "L1704-", - "V1705-", - "K1706-", - "K1707-", - "Y1708-", - "Y1709-", - "S1710-", - "I1711-", - "D1712-", - "N1713-", - "Y1714-", - "L1715-", - "C1716-", - "D1717-", - "T1718-", - "L1719-", - "D1720-", - "D1721-", - "Y1722-", - "I1723-", - "Y1724-", - "T1725-", - "S1726-", - "V1727-", - "E1728-", - "Y1729-", - "N1730-", - "K1731-", - "S1732-", - "Y1733-", - "V1734-", - "L1735-", - "V1736-", - "N1737-", - "D1738-", - "T1739-", - "Y1740-", - "I1741-", - "S1742-", - "Y1743-", - "D1744-", - "Y1745-", - "L1746-", - "E1747-", - "S1748-", - "S1749-", - "G1750-", - "V1751-", - "V1752-", - "V1753-", - "L1754-", - "S1755-", - "C1756-", - "Y1757-", - "E1758-", - "M1759-", - "T1760-", - "I1761-", - "I1762-", - "S1763-", - "L1764-", - "D1765-", - "T1766-", - "K1767-", - "D1768-", - "A1769-", - "K1770-", - "D1771-", - "A1772-", - "I1773-", - "E1774-", - "D1775-", - "V1776-", - "I1777-", - "V1778-", - "A1779-", - "S1780-", - "A1781-", - "V1782-", - "A1783-", - "E1784-", - "A1785-", - "L1786-", - "N1787-", - "D1788-", - "M1789-", - "F1790-", - "K1791-", - "E1792-", - "F1793-", - "D1794-", - "K1795-", - "N1796-", - "V1797-", - "S1798-", - "A1799-", - "I1800-", - "I1801-", - "I1802-", - "K1803-", - "E1804-", - "E1805-", - "D1806-", - "N1807-", - "Y1808-", - "L1809-", - "N1810-", - "S1811-", - "S1812-", - "P1813-", - "D1814-", - "I1815-", - "Y1816-", - "H1817-", - "I1818-", - "I1819-", - "Y1820-", - "I1821-", - "I1822-", - "G1823-", - "G1824-", - "T1825-", - "I1826-", - "L1827-", - "L1828-", - "L1829-", - "L1830-", - "V1831-", - "I1832-", - "I1833-", - "L1834-", - "I1835-", - "L1836-", - "A1837-", - "I1838-", - "Y1839-", - "I1840-", - "A1841-", - "R1842-", - "N1843-", - "K1844-", - "Y1845-", - "R1846-", - "T1847-", - "R1848-", - "K1849-", - "Y1850-", - "E1851-", - "I1852-", - "M1853-", - "K1854-", - "Y1855-", - "D1856-", - "N1857-", - "M1858-", - "S1859-", - "I1860-", - "K1861-", - "S1862-", - "E1863-", - "H1864-", - "H1865-", - "D1866-", - "S1867-", - "L1868-", - "E1869-", - "T1870-", - "V1871-", - "S1872-", - "M1873-", - "E1874-", - "I1875-", - "I1876-", - "D1877-", - "N1878-", - "R1879-", - "Y1880-", - "*1881-" - ] - }, - "labels": { - "aa": "NBT03_gp174: M1-, D2-, S3-, R4-, I5-, A6-, I7-, Y8-, V9-, L10-, V11-, S12-, A13-, S14-, L15-, L16-, Y17-, L18-, V19-, N20-, C21-, H22-, K23-, L24-, V25-, H26-, Y27-, F28-, N29-, L30-, K31-, I32-, N33-, G34-, S35-, D36-, I37-, T38-, N39-, T40-, A41-, D42-, I43-, L44-, L45-, D46-, N47-, Y48-, P49-, I50-, M51-, T52-, F53-, D54-, G55-, K56-, D57-, I58-, Y59-, P60-, S61-, I62-, S63-, F64-, M65-, V66-, G67-, N68-, K69-, L70-, F71-, L72-, D73-, L74-, Y75-, K76-, N77-, I78-, F79-, E80-, E81-, F82-, F83-, R84-, L85-, F86-, R87-, V88-, S89-, V90-, S91-, S92-, Q93-, Y94-, E95-, E96-, L97-, E98-, Y99-, Y100-, Y101-, S102-, C103-, D104-, Y105-, T106-, N107-, N108-, R109-, P110-, T111-, I112-, K113-, Q114-, H115-, Y116-, F117-, Y118-, N119-, G120-, D121-, E122-, Y123-, T124-, E125-, I126-, D127-, R128-, S129-, K130-, K131-, A132-, T133-, N134-, K135-, N136-, S137-, W138-, L139-, I140-, T141-, S142-, G143-, F144-, R145-, L146-, Q147-, K148-, W149-, F150-, D151-, S152-, E153-, D154-, C155-, I156-, I157-, Y158-, L159-, R160-, S161-, L162-, V163-, R164-, R165-, M166-, E167-, D168-, S169-, N170-, K171-, N172-, S173-, K174-, K175-, T176-, *177-; NBT03_gp175: M1-, E2-, S3-, V4-, D5-, F6-, M7-, A8-, V9-, D10-, E11-, Q12-, F13-, H14-, D15-, D16-, L17-, D18-, L19-, W20-, S21-, L22-, S23-, L24-, V25-, D26-, D27-, Y28-, K29-, K30-, H31-, G32-, L33-, G34-, V35-, D36-, C37-, Y38-, V39-, L40-, E41-, P42-, V43-, V44-, D45-, R46-, K47-, I48-, F49-, D50-, R51-, F52-, L53-, L54-, E55-, P56-, I57-, C58-, D59-, P60-, V61-, D62-, V63-, L64-, Y65-, D66-, Y67-, F68-, R69-, I70-, H71-, R72-, D73-, N74-, I75-, D76-, Q77-, Y78-, I79-, V80-, D81-, R82-, L83-, F84-, A85-, Y86-, I87-, T88-, Y89-, K90-, D91-, I92-, I93-, S94-, A95-, L96-, V97-, S98-, K99-, N100-, Y101-, M102-, E103-, D104-, I105-, F106-, S107-, I108-, I109-, I110-, K111-, N112-, C113-, N114-, S115-, V116-, Q117-, D118-, L119-, L120-, L121-, Y122-, Y123-, L124-, S125-, N126-, A127-, Y128-, V129-, E130-, I131-, D132-, I133-, V134-, D135-, L136-, M137-, V138-, D139-, H140-, G141-, A142-, V143-, I144-, Y145-, K146-, I147-, E148-, C149-, L150-, N151-, A152-, Y153-, F154-, R155-, G156-, I157-, C158-, K159-, K160-, E161-, S162-, S163-, V164-, V165-, E166-, F167-, I168-, L169-, N170-, C171-, G172-, I173-, P174-, D175-, E176-, N177-, D178-, V179-, K180-, L181-, D182-, L183-, Y184-, K185-, I186-, I187-, Q188-, Y189-, T190-, R191-, G192-, F193-, L194-, V195-, D196-, E197-, P198-, T199-, V200-, L201-, E202-, I203-, Y204-, K205-, L206-, C207-, I208-, P209-, Y210-, I211-, E212-, D213-, I214-, N215-, Q216-, L217-, D218-, A219-, G220-, G221-, R222-, T223-, L224-, L225-, Y226-, R227-, A228-, I229-, Y230-, A231-, G232-, Y233-, I234-, D235-, L236-, V237-, S238-, W239-, L240-, L241-, E242-, N243-, G244-, A245-, N246-, V247-, N248-, A249-, V250-, M251-, S252-, N253-, G254-, Y255-, T256-, C257-, L258-, D259-, V260-, A261-, V262-, D263-, R264-, G265-, S266-, V267-, I268-, A269-, R270-, R271-, E272-, A273-, H274-, L275-, K276-, I277-, L278-, E279-, I280-, L281-, L282-, R283-, E284-, P285-, L286-, S287-, I288-, D289-, C290-, I291-, K292-, L293-, A294-, I295-, L296-, N297-, N298-, T299-, I300-, E301-, N302-, H303-, D304-, V305-, I306-, K307-, L308-, C309-, I310-, K311-, Y312-, F313-, M314-, M315-, V316-, D317-, Y318-, S319-, L320-, C321-, N322-, V323-, Y324-, A325-, S326-, S327-, L328-, F329-, D330-, Y331-, I332-, I333-, D334-, C335-, K336-, Q337-, E338-, L339-, E340-, Y341-, I342-, R343-, Q344-, M345-, K346-, I347-, H348-, N349-, T350-, T351-, M352-, Y353-, E354-, L355-, I356-, Y357-, N358-, R359-, D360-, K361-, N362-, K363-, H364-, A365-, S366-, H367-, I368-, L369-, H370-, R371-, Y372-, S373-, K374-, H375-, P376-, V377-, L378-, T379-, Q380-, C381-, I382-, T383-, K384-, G385-, F386-, K387-, I388-, Y389-, T390-, E391-, V392-, T393-, E394-, Q395-, V396-, T397-, K398-, A399-, L400-, N401-, R402-, R403-, A404-, L405-, I406-, D407-, E408-, I409-, I410-, N411-, N412-, V413-, S414-, T415-, D416-, D417-, N418-, L419-, L420-, S421-, K422-, L423-, P424-, L425-, E426-, I427-, R428-, D429-, L430-, I431-, V432-, S433-, Q434-, A435-, V436-, I437-, *438-; OPG005: M1-, A2-, S3-, P4-, C5-, A6-, Q7-, F8-, S9-, P10-, C11-, H12-, C13-, H14-, A15-, T16-, K17-, D18-, S19-, L20-, N21-, T22-, V23-, T24-, D25-, V26-, R27-, H28-, C29-, L30-, T31-, E32-, Y33-, I34-, L35-, W36-, V37-, S38-, H39-, R40-, W41-, T42-, H43-, R44-, E45-, S46-, A47-, G48-, P49-, L50-, Y51-, R52-, L53-, L54-, I55-, S56-, F57-, R58-, I59-, D60-, A61-, M62-, E63-, L64-, F65-, G66-, S67-, E68-, L69-, K70-, E71-, F72-, S73-, N74-, S75-, L76-, P77-, W78-, D79-, N80-, I81-, D82-, N83-, C84-, V85-, E86-, I87-, I88-, K89-, C90-, F91-, I92-, R93-, N94-, D95-, S96-, M97-, K98-, T99-, A100-, K101-, E102-, L103-, C104-, A105-, I106-, I107-, G108-, L109-, C110-, T111-, Q112-, S113-, A114-, I115-, V116-, T117-, G118-, R119-, V120-, F121-, N122-, D123-, K124-, Y125-, I126-, D127-, I128-, L129-, L130-, M131-, L132-, R133-, K134-, I135-, L136-, N137-, E138-, N139-, D140-, Y141-, L142-, T143-, L144-, L145-, D146-, H147-, I148-, L149-, T150-, A151-, K152-, Y153-, *154-; OPG188: S269L; OPG210: S1406-, A1407-, M1408-, T1409-, I1410-, K1411-, V1412-, L1413-, P1414-, C1415-, T1416-, V1417-, R1418-, N1419-, K1420-, N1421-, I1422-, D1423-, F1424-, G1425-, Y1426-, N1427-, Y1428-, G1429-, D1430-, I1431-, I1432-, S1433-, N1434-, M1435-, V1436-, Y1437-, L1438-, Q1439-, S1440-, T1441-, S1442-, Q1443-, D1444-, Y1445-, G1446-, D1447-, G1448-, T1449-, K1450-, Y1451-, T1452-, F1453-, K1454-, S1455-, V1456-, T1457-, R1458-, S1459-, D1460-, H1461-, E1462-, C1463-, E1464-, S1465-, S1466-, L1467-, D1468-, L1469-, T1470-, S1471-, K1472-, E1473-, V1474-, T1475-, V1476-, T1477-, C1478-, P1479-, A1480-, F1481-, S1482-, I1483-, P1484-, R1485-, N1486-, I1487-, S1488-, T1489-, Y1490-, E1491-, G1492-, L1493-, C1494-, F1495-, S1496-, V1497-, T1498-, T1499-, S1500-, K1501-, D1502-, H1503-, C1504-, A1505-, T1506-, G1507-, I1508-, G1509-, W1510-, L1511-, K1512-, S1513-, S1514-, G1515-, Y1516-, G1517-, K1518-, E1519-, D1520-, A1521-, D1522-, K1523-, P1524-, R1525-, A1526-, C1527-, F1528-, H1529-, H1530-, W1531-, N1532-, Y1533-, Y1534-, T1535-, L1536-, S1537-, L1538-, D1539-, Y1540-, Y1541-, C1542-, S1543-, Y1544-, E1545-, D1546-, I1547-, W1548-, R1549-, S1550-, T1551-, W1552-, P1553-, D1554-, Y1555-, D1556-, P1557-, C1558-, K1559-, S1560-, Y1561-, I1562-, H1563-, I1564-, E1565-, Y1566-, R1567-, D1568-, T1569-, W1570-, I1571-, E1572-, S1573-, N1574-, V1575-, L1576-, Q1577-, Q1578-, P1579-, P1580-, Y1581-, T1582-, F1583-, E1584-, F1585-, I1586-, H1587-, D1588-, N1589-, S1590-, N1591-, E1592-, Y1593-, V1594-, D1595-, K1596-, E1597-, I1598-, S1599-, N1600-, K1601-, L1602-, N1603-, D1604-, L1605-, Y1606-, N1607-, E1608-, Y1609-, K1610-, K1611-, I1612-, M1613-, E1614-, Y1615-, S1616-, D1617-, G1618-, S1619-, L1620-, P1621-, A1622-, S1623-, I1624-, N1625-, R1626-, L1627-, A1628-, K1629-, A1630-, L1631-, T1632-, S1633-, E1634-, G1635-, R1636-, E1637-, I1638-, A1639-, S1640-, V1641-, N1642-, I1643-, D1644-, G1645-, N1646-, L1647-, L1648-, D1649-, I1650-, A1651-, Y1652-, Q1653-, A1654-, D1655-, K1656-, E1657-, K1658-, M1659-, A1660-, D1661-, I1662-, Q1663-, T1664-, R1665-, I1666-, N1667-, D1668-, I1669-, I1670-, R1671-, D1672-, L1673-, F1674-, I1675-, H1676-, T1677-, L1678-, S1679-, D1680-, K1681-, D1682-, I1683-, K1684-, D1685-, I1686-, I1687-, E1688-, S1689-, E1690-, E1691-, G1692-, K1693-, R1694-, C1695-, C1696-, I1697-, I1698-, D1699-, V1700-, K1701-, N1702-, N1703-, L1704-, V1705-, K1706-, K1707-, Y1708-, Y1709-, S1710-, I1711-, D1712-, N1713-, Y1714-, L1715-, C1716-, D1717-, T1718-, L1719-, D1720-, D1721-, Y1722-, I1723-, Y1724-, T1725-, S1726-, V1727-, E1728-, Y1729-, N1730-, K1731-, S1732-, Y1733-, V1734-, L1735-, V1736-, N1737-, D1738-, T1739-, Y1740-, I1741-, S1742-, Y1743-, D1744-, Y1745-, L1746-, E1747-, S1748-, S1749-, G1750-, V1751-, V1752-, V1753-, L1754-, S1755-, C1756-, Y1757-, E1758-, M1759-, T1760-, I1761-, I1762-, S1763-, L1764-, D1765-, T1766-, K1767-, D1768-, A1769-, K1770-, D1771-, A1772-, I1773-, E1774-, D1775-, V1776-, I1777-, V1778-, A1779-, S1780-, A1781-, V1782-, A1783-, E1784-, A1785-, L1786-, N1787-, D1788-, M1789-, F1790-, K1791-, E1792-, F1793-, D1794-, K1795-, N1796-, V1797-, S1798-, A1799-, I1800-, I1801-, I1802-, K1803-, E1804-, E1805-, D1806-, N1807-, Y1808-, L1809-, N1810-, S1811-, S1812-, P1813-, D1814-, I1815-, Y1816-, H1817-, I1818-, I1819-, Y1820-, I1821-, I1822-, G1823-, G1824-, T1825-, I1826-, L1827-, L1828-, L1829-, L1830-, V1831-, I1832-, I1833-, L1834-, I1835-, L1836-, A1837-, I1838-, Y1839-, I1840-, A1841-, R1842-, N1843-, K1844-, Y1845-, R1846-, T1847-, R1848-, K1849-, Y1850-, E1851-, I1852-, M1853-, K1854-, Y1855-, D1856-, N1857-, M1858-, S1859-, I1860-, K1861-, S1862-, E1863-, H1864-, H1865-, D1866-, S1867-, L1868-, E1869-, T1870-, V1871-, S1872-, M1873-, E1874-, I1875-, I1876-, D1877-, N1878-, R1879-, Y1880-, *1881-" - } - } - }, - { - "name": "9000426", - "node_attrs": { - "div": 557, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "9000426" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536800" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "T190786-", - "T190787-", - "A196604-" - ], - "NBT03_gp174": [ - "I126X", - "*177X" - ] - }, - "labels": { - "aa": "NBT03_gp174: I126X, *177X" - } - } - }, - { - "name": "Monkeypox/PT0564/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-09-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "Monkeypox/PT0564/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555635" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C23422T", - "G54619A", - "G68997A", - "C69705T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C156100T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG039": [ - "E233K" - ] - }, - "labels": { - "aa": "OPG039: E233K" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI456", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI456" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP615330" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C3850T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T" - ] - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-089756/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-089756/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP743955" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C124121T", - "C133453T", - "-179173A", - "-179174T", - "-179175T", - "A196604-" - ] - } - } - }, - { - "name": "MPXV_USA_2022_IN0006", - "node_attrs": { - "div": 560, - "author": { - "author": "Gigante,C., Culbertson,M., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Weigand,M., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Pope,B., Li,Y.", - "value": "Gigante,C., Culbertson,M., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Weigand,M., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Pope,B., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV_USA_2022_IN0006" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ320518" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T22135C", - "G52232A", - "C119838T", - "A136513-", - "T136514-", - "C136515-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG037": [ - "H100R" - ], - "OPG071": [ - "S736L" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG037: H100R; OPG071: S736L; OPG153: D385-" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI724", - "node_attrs": { - "div": 557, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI724" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ547751" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179173A", - "-179174T", - "-179175T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_218/Belgium/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-08-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_218/Belgium/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR095036" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C25828T", - "G107496A", - "G109463A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG042": [ - "E424K" - ] - }, - "labels": { - "aa": "OPG042: E424K" - } - } - }, - { - "name": "MPXV_USA_2022_NE0006", - "node_attrs": { - "div": 560, - "author": { - "author": "Li,C.M.", - "value": "Li,C.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV_USA_2022_NE0006" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR209326" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G11924A", - "G34800A", - "T133099-", - "A136513-", - "T136514-", - "C136515-", - "G160406A", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG023": [ - "S326L" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG023: S326L; OPG153: D385-" - } - } - }, - { - "name": "NODE_0000243", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C17048T", - "G93828A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G177009A", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG029": [ - "D8N" - ], - "OPG113": [ - "E700K" - ], - "OPG205": [ - "E452K" - ] - }, - "labels": { - "aa": "OPG029: D8N; OPG113: E700K; OPG205: E452K" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI633", - "node_attrs": { - "div": 561, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-11-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI633" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ159028" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C41131T" - ], - "OPG060": [ - "E18K" - ] - }, - "labels": { - "aa": "OPG060: E18K" - } - } - }, - { - "name": "MPXV/PT0626/2023", - "node_attrs": { - "div": 567, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2023-03-21" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV/PT0626/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ735077" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A571-", - "G572-", - "C10929T", - "C22179T", - "G39515A", - "G77076A", - "G129659A", - "C129949T", - "G139167A", - "G196594-", - "T196595-", - "-196601A" - ], - "OPG023": [ - "E658K" - ], - "OPG151": [ - "E246K" - ] - }, - "labels": { - "aa": "OPG023: E658K; OPG151: E246K" - } - } - } - ] - }, - { - "name": "NODE_0000244", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C11401T", - "A136513-", - "T136514-", - "C136515-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_NV0005", - "node_attrs": { - "div": 560, - "author": { - "author": "Gigante,C., Buttery,E., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Knipe,K., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Raman,D., Li,Y.", - "value": "Gigante,C., Buttery,E., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Knipe,K., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Raman,D., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-10-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV_USA_2022_NV0005" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ427112" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C72269T", - "T133099-", - "G140194A", - "G158318A", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-" - ], - "OPG092": [ - "D227N" - ], - "OPG159": [ - "D143N" - ], - "OPG160": [ - "S294L" - ] - }, - "labels": { - "aa": "OPG092: D227N; OPG159: D143N; OPG160: S294L" - } - } - }, - { - "name": "MPXV_USA_2022_TX0051", - "node_attrs": { - "div": 560, - "author": { - "author": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y.", - "value": "Gigante,C., Kubin,G., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., White,S., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV_USA_2022_TX0051" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ721942" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G23673A", - "G50121A", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG039": [ - "S149L" - ], - "OPG069": [ - "E46K" - ] - }, - "labels": { - "aa": "OPG039: S149L; OPG069: E46K" - } - } - } - ] - }, - { - "name": "NODE_0000245", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G155698A" - ] - } - }, - "children": [ - { - "name": "MPXV/UZ_REGA_180/Belgium/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-07-27" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_180/Belgium/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR086989" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C7037T", - "G10930A", - "C109896T", - "T133099-", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG129": [ - "R370K" - ] - }, - "labels": { - "aa": "OPG129: R370K" - } - } - }, - { - "name": "NODE_0000246", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G161575A", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "-196603A" - ] - } - }, - "children": [ - { - "name": "Monkeypox/PT0377/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-07-06" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "Monkeypox/PT0377/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555473" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ] - } - } - }, - { - "name": "Monkeypox/PT0586/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "Monkeypox/PT0586/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555655" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C54306T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C167451T" - ], - "OPG071": [ - "E45K" - ] - }, - "labels": { - "aa": "OPG071: E45K" - } - } - }, - { - "name": "MPXV/UZ_REGA_149/Belgium/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-07-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_149/Belgium/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR086958" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133099-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000247", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C22739T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG038": [ - "E141K" - ] - }, - "labels": { - "aa": "OPG038: E141K" - } - }, - "children": [ - { - "name": "CVR_MPXV1a", - "node_attrs": { - "div": 558, - "author": { - "author": "Filipe,A., Tong,L., Vattipally,S.B., Maclean,A., Gunson,R., Holden,M.T.G., Barr,D., Ho,A., Palmarini,M., Rambaut,A., Robertson,D.L., Thomson,E.C.", - "value": "Filipe,A., Tong,L., Vattipally,S.B., Maclean,A., Gunson,R., Holden,M.T.G., Barr,D., Ho,A., Palmarini,M., Rambaut,A., Robertson,D.L., Thomson,E.C." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics" - }, - "date": { - "value": "2022-05-15" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "CVR_MPXV1a" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON808413" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133098-", - "T133099-", - "T133100-", - "T133101-", - "T133102-", - "C133103-", - "A136513-", - "T136514-", - "C136515-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI184", - "node_attrs": { - "div": 560, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI184" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP018606" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G21655A", - "G135221A", - "C179163-", - "C179172-" - ], - "OPG037": [ - "S260L" - ] - }, - "labels": { - "aa": "OPG037: S260L" - } - } - }, - { - "name": "MPXV_UK_2022_9000179", - "node_attrs": { - "div": 558, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-06-26" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000179" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205128" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C" - ] - } - } - }, - { - "name": "MPX_dDDHx_9000207", - "node_attrs": { - "div": 559, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPX_dDDHx_9000207" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415188" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A33221-", - "T33222-", - "A33223-", - "T33224-", - "T33225-", - "C33226-", - "T33227-", - "C33228-", - "A33229-", - "T33230-", - "T33231-", - "G33232-", - "C33233-", - "T33234-", - "C144199T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C" - ], - "OPG050": [ - "S59-", - "N60-", - "E61-", - "N62-", - "I63X", - "*76X" - ] - }, - "labels": { - "aa": "OPG050: S59-, N60-, E61-, N62-, I63X, *76X" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI394", - "node_attrs": { - "div": 563, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI394" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP523997" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G71922A", - "G142700A", - "C151213T", - "G152979A", - "C179163-", - "C179172-", - "G184562A" - ], - "OPG163": [ - "D167N" - ] - }, - "labels": { - "aa": "OPG163: D167N" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI515", - "node_attrs": { - "div": 560, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI515" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP689668" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C144256T", - "G170785A", - "C179163-", - "C179172-" - ], - "OPG198": [ - "E250K" - ] - }, - "labels": { - "aa": "OPG198: E250K" - } - } - }, - { - "name": "NY-NYCPHL-000083", - "node_attrs": { - "div": 558, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-06-16" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "NY-NYCPHL-000083" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ504391" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI064", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI064" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON813264" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C179163-", - "C179172-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI015", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI015" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON694331" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C179163-", - "C179172-", - "A192440-", - "T192441-", - "A192442-", - "A192443-", - "G192444-", - "T192445-", - "T192446-", - "A192447-", - "G192448-", - "T192449-", - "T192450-", - "A192451-", - "A192452-", - "G192453-", - "T192454-", - "C192455-", - "A192456-", - "T192457-", - "A192458-", - "A192459-", - "G192460-", - "T192461-", - "T192462-", - "A192463-", - "G192464-", - "T192465-", - "T192466-", - "A192467-", - "A192468-", - "G192469-", - "T192470-", - "C192471-" - ] - } - } - }, - { - "name": "hMPXV/Austria/MUW1527495/2022", - "node_attrs": { - "div": 558, - "author": { - "author": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W.", - "value": "Camp,J.V., Redlberger-Fritz,M., Aberle,S.W." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Medical University of Vienna, Center for Virology" - }, - "date": { - "value": "2022-06-21" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "hMPXV/Austria/MUW1527495/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP019276" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Austria" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "NODE_0000250", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C22740T", - "C38937T", - "C179163-", - "C179172-" - ], - "OPG056": [ - "R33Q" - ] - }, - "labels": { - "aa": "OPG056: R33Q" - } - }, - "children": [ - { - "name": "MPX/PT0114/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-07-15" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPX/PT0114/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP245348" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPX_KV9qz9_9000349", - "node_attrs": { - "div": 561, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "MPX_KV9qz9_9000349" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415276" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C67659T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C" - ], - "OPG085": [ - "M291I" - ] - }, - "labels": { - "aa": "OPG085: M291I" - } - } - }, - { - "name": "Monkeypox/PT0531/2022", - "node_attrs": { - "div": 563, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "Monkeypox/PT0531/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555602" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6376A", - "G136834A", - "G186423A" - ], - "OPG210": [ - "E1690K" - ] - }, - "labels": { - "aa": "OPG210: E1690K" - } - } - }, - { - "name": "Monkeypox/PT0570/2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-09-02" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.1" - }, - "strain_original": { - "value": "Monkeypox/PT0570/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555641" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G74362A", - "A136537-", - "T136538-", - "C136539-", - "A136540-", - "T136541-", - "C136542-", - "A136543-", - "T136544-", - "C136545-", - "A136546-", - "T136547-", - "C136548-", - "A136549-", - "T136550-", - "C136551-", - "A136552-", - "T136553-", - "C136554-", - "T136555-", - "A136556-", - "T136557-", - "G136558-", - "A136559-", - "T136560-", - "C177240T" - ], - "OPG094": [ - "A195T" - ], - "OPG153": [ - "I370-", - "I371-", - "D372-", - "D373-", - "D374-", - "D375-", - "D376-", - "D377-" - ], - "OPG205": [ - "Q529*" - ] - }, - "labels": { - "aa": "OPG094: A195T; OPG153: I370-, I371-, D372-, D373-, D374-, D375-, D376-, D377-; OPG205: Q529*" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000251", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179175T", - "G186165A" - ], - "OPG210": [ - "D1604N" - ] - }, - "labels": { - "aa": "OPG210: D1604N", - "clade": "B.1.2" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI124", - "node_attrs": { - "div": 557, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI124" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON929079" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "MPXV_USA_2022_CA0005", - "node_attrs": { - "div": 558, - "author": { - "author": "Gigante,C.M., Ventura,J., Seabolt,M.H., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nash,J., Li,Y.", - "value": "Gigante,C.M., Ventura,J., Seabolt,M.H., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nash,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV_USA_2022_CA0005" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP185716" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C43068T", - "A136513-", - "T136514-", - "C136515-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "MPXV_UK_2022_9000100", - "node_attrs": { - "div": 557, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-06-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000100" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205088" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T" - ] - } - } - }, - { - "name": "MPXV_UK_2022_9000186", - "node_attrs": { - "div": 558, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-06-29" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000186" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205131" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G92048A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T" - ] - } - } - }, - { - "name": "MPX_fZLVcc_9000227", - "node_attrs": { - "div": 557, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPX_fZLVcc_9000227" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415202" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI673", - "node_attrs": { - "div": 557, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI673" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ274892" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A152668-", - "T152680-", - "C179163-", - "C179172-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00419/2022", - "node_attrs": { - "div": 566, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-11-22" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00419/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503812" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C3405T", - "G5375A", - "C72914T", - "C112712T", - "G129749A", - "G133004A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "G154098A", - "C166171T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "G182486A", - "C191835T", - "G193805A" - ], - "NBT03_gp175": [ - "A261V" - ], - "OPG015": [ - "A261V" - ], - "OPG092": [ - "D12N" - ], - "OPG132": [ - "D277N" - ], - "OPG151": [ - "E276K" - ], - "OPG191": [ - "S4L" - ] - }, - "labels": { - "aa": "NBT03_gp175: A261V; OPG015: A261V; OPG092: D12N; OPG132: D277N; OPG151: E276K; OPG191: S4L" - } - } - }, - { - "name": "NODE_0000252", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G61253A", - "G143789A" - ], - "OPG080": [ - "R256C" - ], - "OPG165": [ - "D92N" - ] - }, - "labels": { - "aa": "OPG080: R256C; OPG165: D92N" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI109", - "node_attrs": { - "div": 560, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI109" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON929067" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C20992T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG036": [ - "D25N" - ] - }, - "labels": { - "aa": "OPG036: D25N" - } - } - }, - { - "name": "MPXV_UK_2022_9000066", - "node_attrs": { - "div": 560, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-06-07" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000066" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205072" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C147168T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T" - ], - "OPG171": [ - "L61F" - ] - }, - "labels": { - "aa": "OPG171: L61F" - } - } - } - ] - }, - { - "name": "NODE_0000253", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150556G", - "-150559G", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "C188391T" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI072", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI072" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON853658" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "MPXV_UK_2022_9000092", - "node_attrs": { - "div": 558, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-05-25" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000092" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205083" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "G150556-", - "G150559-" - ] - } - } - }, - { - "name": "MPXV_UK_2022_9000097", - "node_attrs": { - "div": 558, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-06-06" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000097" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205086" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "G150556-", - "G150559-" - ] - } - } - }, - { - "name": "9000408", - "node_attrs": { - "div": 558, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "9000408" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536784" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "9000416", - "node_attrs": { - "div": 558, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "9000416" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536790" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "A196604-" - ] - } - } - }, - { - "name": "Slovenia-MPXV-42-2022", - "node_attrs": { - "div": 563, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "Slovenia-MPXV-42-2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605583" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A138-", - "-595T", - "C17614A", - "C27187T", - "G111484A", - "G147305A", - "G150551-", - "G150556-", - "G150559-", - "C159401A", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG030": [ - "V74L" - ], - "OPG043": [ - "D257N" - ], - "OPG130": [ - "T140I" - ], - "OPG185": [ - "S162Y" - ] - }, - "labels": { - "aa": "OPG030: V74L; OPG043: D257N; OPG130: T140I; OPG185: S162Y" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI446", - "node_attrs": { - "div": 561, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI446" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP615326" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C101983T", - "C141757T", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C160426T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A" - ], - "OPG121": [ - "S65L" - ] - }, - "labels": { - "aa": "OPG121: S65L" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI461", - "node_attrs": { - "div": 559, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI461" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP615335" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G6771A", - "C99166T", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T" - ] - } - } - }, - { - "name": "MPXV_USA_2022_TN0011", - "node_attrs": { - "div": 562, - "author": { - "author": "Gigante,C., Thomas,L., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Dunn,J., Li,Y.", - "value": "Gigante,C., Thomas,L., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Dunn,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV_USA_2022_TN0011" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ320505" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C1860T", - "C6105T", - "G77797T", - "G150551-", - "G150556-", - "G150559-", - "G173397A", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "G191105A", - "G195350A", - "-196603A" - ], - "NBT03_gp175": [ - "D18N" - ], - "OPG002": [ - "D298N" - ], - "OPG015": [ - "D18N" - ], - "OPG099": [ - "V45L" - ] - }, - "labels": { - "aa": "NBT03_gp175: D18N; OPG002: D298N; OPG015: D18N; OPG099: V45L" - } - } - }, - { - "name": "hMpxV/USA/CA-CDPH-1MPX1000112/2022", - "node_attrs": { - "div": 567, - "author": { - "author": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J.", - "value": "Probert,W., Espinosa,A., Kath,C., Haw,M., O'Neil,R., Bell,J., Hacker,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "date": { - "value": "2022-12-14" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "hMpxV/USA/CA-CDPH-1MPX1000112/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ348860" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C7705T", - "C39334G", - "G50617A", - "G62896A", - "G89947A", - "C110394T", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G150753A", - "A158920T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "G183899A" - ], - "OPG057": [ - "A288P" - ], - "OPG070": [ - "D10N" - ], - "OPG082": [ - "S186L" - ], - "OPG110": [ - "E106K" - ], - "OPG129": [ - "R204Q" - ], - "OPG185": [ - "T2S" - ] - }, - "labels": { - "aa": "OPG057: A288P; OPG070: D10N; OPG082: S186L; OPG110: E106K; OPG129: R204Q; OPG185: T2S" - } - } - }, - { - "name": "NY-NYCPHL-000756", - "node_attrs": { - "div": 558, - "author": { - "author": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-07-11" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "NY-NYCPHL-000756" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468645" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "NY-NYCPHL-000773", - "node_attrs": { - "div": 561, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-07-12" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "NY-NYCPHL-000773" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468792" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C37803T", - "C78473T", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150567T", - "G159289A", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG056": [ - "R411K" - ], - "OPG185": [ - "E125K" - ] - }, - "labels": { - "aa": "OPG056: R411K; OPG185: E125K" - } - } - }, - { - "name": "NY-NYCPHL-000404", - "node_attrs": { - "div": 558, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-08-24" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "NY-NYCPHL-000404" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468979" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "G150556-", - "G150559-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00404/2023", - "node_attrs": { - "div": 565, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2023-01-10" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00404/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503827" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G25309A", - "G28271A", - "G112785A", - "T118096C", - "G133968T", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "C165231T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "C180371T" - ], - "OPG040": [ - "S57L" - ], - "OPG044": [ - "D61N" - ], - "OPG136": [ - "M498V" - ], - "OPG190": [ - "S37L" - ] - }, - "labels": { - "aa": "OPG040: S57L; OPG044: D61N; OPG136: M498V; OPG190: S37L" - } - } - }, - { - "name": "MPXV/UZ_REGA_164/Belgium/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-07-27" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_164/Belgium/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR086973" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G135633A", - "G150551-", - "G150556-", - "G150559-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "NODE_0000254", - "node_attrs": { - "div": 567, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T11371C", - "G34303A", - "C85322T", - "G92048A", - "G123119A", - "G129583A", - "C140931T", - "G150551-", - "G150556-", - "G150559-", - "C153104T", - "C178378T" - ], - "OPG053": [ - "P130S" - ], - "OPG143": [ - "S66L" - ], - "OPG180": [ - "S138F" - ] - }, - "labels": { - "aa": "OPG053: P130S; OPG143: S66L; OPG180: S138F" - } - }, - "children": [ - { - "name": "9000231", - "node_attrs": { - "div": 567, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "9000231" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP413713" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPX_TcUINH_9000230", - "node_attrs": { - "div": 567, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPX_TcUINH_9000230" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415205" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000255", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G176439A" - ], - "OPG205": [ - "D262N" - ] - }, - "labels": { - "aa": "OPG205: D262N" - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00295/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-11-01" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00295/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP890528" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C27730T", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG043": [ - "D76N" - ] - }, - "labels": { - "aa": "OPG043: D76N" - } - } - }, - { - "name": "NY-NYCPHL-000395", - "node_attrs": { - "div": 564, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-08-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "NY-NYCPHL-000395" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468975" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G13224A", - "C36493T", - "C55072T", - "C67595T", - "T148510C", - "G150551-", - "G150556-", - "G150559-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "NBT03_gp052": [ - "D24N" - ], - "OPG024": [ - "S2L" - ], - "OPG085": [ - "D313N" - ], - "OPG174": [ - "K296E" - ] - }, - "labels": { - "aa": "NBT03_gp052: D24N; OPG024: S2L; OPG085: D313N; OPG174: K296E" - } - } - } - ] - }, - { - "name": "NODE_0000256", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G70089A", - "G137585A", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G175165A", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "T196584-", - "C196585-", - "A196586-" - ], - "OPG089": [ - "R75K" - ], - "OPG153": [ - "S28F" - ], - "OPG204": [ - "E212K" - ] - }, - "labels": { - "aa": "OPG089: R75K; OPG153: S28F; OPG204: E212K" - } - }, - "children": [ - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00342/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-10-26" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00342/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP920680" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox virus/Human/USA/CA-LACPHL-MA00386/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-10-25" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "Monkeypox virus/Human/USA/CA-LACPHL-MA00386/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ330994" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000257", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G2126A", - "C64132T", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C154736T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "G183791A", - "C195084T" - ], - "OPG002": [ - "S209L" - ], - "OPG083": [ - "M195I" - ], - "OPG181": [ - "P109S" - ] - }, - "labels": { - "aa": "OPG002: S209L; OPG083: M195I; OPG181: P109S" - } - }, - "children": [ - { - "name": "hMpxV/USA/CACDPH1MPX1000172/2023", - "node_attrs": { - "div": 564, - "author": { - "author": "Kath,C., Haw,M., Espinosa,A., Hacker,J.", - "value": "Kath,C., Haw,M., Espinosa,A., Hacker,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "date": { - "value": "2023-01-12" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "hMpxV/USA/CACDPH1MPX1000172/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR178739" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T548-", - "A549-", - "A550-", - "G39327A", - "C110699T" - ], - "OPG057": [ - "A290V" - ] - }, - "labels": { - "aa": "OPG057: A290V" - } - } - }, - { - "name": "hMpxV/USA/CACDPH1MPX1000193/2023", - "node_attrs": { - "div": 570, - "author": { - "author": "Kath,C., Haw,M., Espinosa,A., Hacker,J.", - "value": "Kath,C., Haw,M., Espinosa,A., Hacker,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDPH, VRDL" - }, - "date": { - "value": "2023-02-14" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "hMpxV/USA/CACDPH1MPX1000193/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR178741" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G10224A", - "A31053G", - "T39348C", - "A78942G", - "T130733C", - "G138728A", - "A155151C", - "T187664C" - ], - "OPG021": [ - "R213Q" - ], - "OPG047": [ - "C48R" - ], - "OPG057": [ - "D283G" - ], - "OPG101": [ - "T153A" - ], - "OPG151": [ - "C604R" - ], - "OPG156": [ - "H228Y" - ], - "OPG181": [ - "E247A" - ] - }, - "labels": { - "aa": "OPG021: R213Q; OPG047: C48R; OPG057: D283G; OPG101: T153A; OPG151: C604R; OPG156: H228Y; OPG181: E247A" - } - } - } - ] - }, - { - "name": "NODE_0000258", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T26669C", - "G96073A", - "G115235A", - "C125294T", - "G150551-", - "G150556-", - "G150559-" - ], - "OPG117": [ - "D9N" - ] - }, - "labels": { - "aa": "OPG117: D9N" - } - }, - "children": [ - { - "name": "BOL-UNIMOL-MPX-293428-L", - "node_attrs": { - "div": 562, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "date": { - "value": "2022-10-29" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "BOL-UNIMOL-MPX-293428-L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP959060" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000259", - "node_attrs": { - "div": 563, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C135868T" - ] - } - }, - "children": [ - { - "name": "BOL-UNIMOL-MPX-293613-L", - "node_attrs": { - "div": 563, - "author": { - "author": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D.", - "value": "Loyola,S., Fernandez-Ruiz,M., Torres-Pacheco,J., Franco-Munoz,C., Laiton-Donato,K., Ruiz-Moreno,H., Mercado-Reyes,M., Gomez-Camargo,D." - }, - "region": { - "value": "South America" - }, - "institution": { - "value": "Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)" - }, - "date": { - "value": "2022-10-11" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "BOL-UNIMOL-MPX-293613-L" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP959061" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Colombia" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Germany/2022/RKI632", - "node_attrs": { - "div": 564, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-11-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI632" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ159027" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G77052A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000260", - "node_attrs": { - "div": 564, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G8638A", - "C21548T", - "C47820T", - "C68218T", - "G150551-", - "G150556-", - "G150559-", - "C188236T", - "C188339T" - ], - "OPG037": [ - "D296N" - ], - "OPG085": [ - "R105Q" - ] - }, - "labels": { - "aa": "OPG037: D296N; OPG085: R105Q" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-041886/2023", - "node_attrs": { - "div": 564, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2023-04-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-041886/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ979622" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133098-", - "T133099-" - ] - } - } - }, - { - "name": "MpxV/human/USA/WA-UW-048370/2023", - "node_attrs": { - "div": 566, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2023-04-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-048370/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ979623" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C70252T", - "C102741T" - ], - "OPG122": [ - "S105L" - ] - }, - "labels": { - "aa": "OPG122: S105L" - } - } - }, - { - "name": "NODE_0000261", - "node_attrs": { - "div": 566, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G12239A", - "G12488A", - "-196603A" - ], - "OPG023": [ - "S138L", - "S221F" - ] - }, - "labels": { - "aa": "OPG023: S138L, S221F" - } - }, - "children": [ - { - "name": "MpxV/human/USA/WA-UW-126801/2022", - "node_attrs": { - "div": 566, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2022-12-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-126801/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ503756" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MpxV/human/USA/WA-UW-028492/2023", - "node_attrs": { - "div": 566, - "author": { - "author": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L.", - "value": "Sereewit,J., Xie,H., Roychoudhury,P., Greninger,A.L." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "UW Virology, Laboratory Medicine" - }, - "date": { - "value": "2023-02-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MpxV/human/USA/WA-UW-028492/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ979624" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000262", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G45781A", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T" - ], - "OPG064": [ - "H40Y" - ] - }, - "labels": { - "aa": "OPG064: H40Y" - } - }, - "children": [ - { - "name": "Monkeypox/PT0554/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-30" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "Monkeypox/PT0554/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555625" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G29102A", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG045": [ - "S54L" - ] - }, - "labels": { - "aa": "OPG045: S54L" - } - } - }, - { - "name": "B1221119", - "node_attrs": { - "div": 564, - "author": { - "author": "Bajwa,M.I., Miller,H.", - "value": "Bajwa,M.I., Miller,H." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Delaware Public Health Lab, Sequencing/Bioinformatics" - }, - "date": { - "value": "2022-11-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "B1221119" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP935996" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G2146A", - "C106706T", - "G129859A", - "C138639T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G153765A", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "C195064T" - ], - "OPG125": [ - "E317K" - ], - "OPG156": [ - "M257I" - ] - }, - "labels": { - "aa": "OPG125: E317K; OPG156: M257I" - } - } - }, - { - "name": "NY-NYCPHL-000011", - "node_attrs": { - "div": 559, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-06-26" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "NY-NYCPHL-000011" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469015" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "NY-NYCPHL-000149", - "node_attrs": { - "div": 559, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-06-26" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "NY-NYCPHL-000149" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469153" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150565G", - "-150566A", - "-150567T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV_USA_2022_PA0002", - "node_attrs": { - "div": 560, - "author": { - "author": "Gigante,C., Xia,D., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Plipat,N., Li,Y.", - "value": "Gigante,C., Xia,D., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Plipat,N., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV_USA_2022_PA0002" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ702770" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "C157105T", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - } - ] - }, - { - "name": "NODE_0000263", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150557A", - "-150558T", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150565G", - "-150566A", - "-150567T", - "T157527C", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/ON/RKI317", - "node_attrs": { - "div": 559, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI317" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP355574" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150564T", - "A188349-" - ] - } - } - }, - { - "name": "9000327", - "node_attrs": { - "div": 562, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "9000327" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP413715" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C114099T", - "G149805A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "G150565-", - "A150566-", - "T150567-", - "G166317A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C" - ], - "OPG133": [ - "R533Q" - ], - "OPG175": [ - "E122K" - ], - "OPG191": [ - "D53N" - ] - }, - "labels": { - "aa": "OPG133: R533Q; OPG175: E122K; OPG191: D53N" - } - } - }, - { - "name": "Monkeypox/PT0387/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-07-12" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "Monkeypox/PT0387/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555483" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150564T", - "G154098A" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI566", - "node_attrs": { - "div": 560, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI566" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP764624" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C7170T", - "-150564T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI848", - "node_attrs": { - "div": 559, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI848" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773467" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A" - ] - } - } - }, - { - "name": "NODE_0000264", - "node_attrs": { - "div": 563, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150087A", - "C156429T", - "C156509T", - "G177872A" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI260", - "node_attrs": { - "div": 563, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI260" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP215279" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150564T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI849", - "node_attrs": { - "div": 563, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.2" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI849" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773468" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T" - ] - } - } - } - ] - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000269", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C25644T", - "A179191-", - "T179192-", - "T179193-" - ] - }, - "labels": { - "clade": "B.1.7" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI185", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI185" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP018607" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C40784T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "MPXV_UK_2022_9000192", - "node_attrs": { - "div": 558, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-07-05" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000192" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205137" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G53441A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179191A", - "-179192T", - "-179193T" - ], - "OPG071": [ - "S333L" - ] - }, - "labels": { - "aa": "OPG071: S333L" - } - } - }, - { - "name": "Monkeypox/PT0135/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-07-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "Monkeypox/PT0135/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP324458" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "-196603A" - ] - } - } - }, - { - "name": "9000399", - "node_attrs": { - "div": 558, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "9000399" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536777" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179191A", - "-179192T", - "-179193T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "G180608A" - ], - "OPG209": [ - "E31K" - ] - }, - "labels": { - "aa": "OPG209: E31K" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI720", - "node_attrs": { - "div": 557, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI720" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ547747" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150566A", - "-150567T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179191A", - "-179192T", - "-179193T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_245/Belgium/2022", - "node_attrs": { - "div": 558, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-08-16" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_245/Belgium/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR095063" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G105860A", - "T149487-", - "A149488-", - "C149489-", - "G149490-", - "T149491-", - "T149492-", - "G149493-", - "A149494-", - "A149495-", - "C149496-", - "A149497-", - "A149498-", - "G149499-", - "T149500-", - "C149501-", - "C149502-", - "A149503-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179191A", - "-179192T", - "-179193T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG175": [ - "Y16-", - "V17-", - "E18-", - "Q19-", - "V20-", - "H21X", - "*126X" - ] - }, - "labels": { - "aa": "OPG175: Y16-, V17-, E18-, Q19-, V20-, H21X, *126X" - } - } - }, - { - "name": "Monkeypox/PT0031/2022", - "node_attrs": { - "div": 557, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-05-26" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "Monkeypox/PT0031/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON843170" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "MPXV_UK_2022_9000078", - "node_attrs": { - "div": 557, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-06-14" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000078" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205081" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179191A", - "-179192T", - "-179193T" - ] - } - } - }, - { - "name": "MPXV_UK_2022_9000064", - "node_attrs": { - "div": 557, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-06-06" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000064" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205070" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179191A", - "-179192T", - "-179193T" - ] - } - } - }, - { - "name": "MPXV_USA_2022_CO0006", - "node_attrs": { - "div": 558, - "author": { - "author": "Gigante,C.M., Steidley,B., Seabolt,M.H., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Davizon,E., Li,Y.", - "value": "Gigante,C.M., Steidley,B., Seabolt,M.H., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Davizon,E., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV_USA_2022_CO0006" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP225963" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "C186970T" - ], - "OPG210": [ - "S1872F" - ] - }, - "labels": { - "aa": "OPG210: S1872F" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI642", - "node_attrs": { - "div": 561, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI642" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ159037" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C66249T", - "C88644A", - "C104134T", - "C112638T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179191A", - "-179192T", - "-179193T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T" - ], - "OPG109": [ - "K268N" - ], - "OPG123": [ - "A313T" - ] - }, - "labels": { - "aa": "OPG109: K268N; OPG123: A313T" - } - } - }, - { - "name": "NODE_0000158", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C1735T", - "T149447C", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179191A", - "-179192T", - "-179193T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "G195475A", - "-196603A" - ] - } - }, - "children": [ - { - "name": "MPXV_USA_2022_TN0013", - "node_attrs": { - "div": 560, - "author": { - "author": "Gigante,C., Thomas,L., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Dunn,J., Li,Y.", - "value": "Gigante,C., Thomas,L., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Burroughs,M.S., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Dunn,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV_USA_2022_TN0013" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ320507" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C31714T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-" - ], - "OPG048": [ - "G151S" - ] - }, - "labels": { - "aa": "OPG048: G151S" - } - } - }, - { - "name": "NY-NYCPHL-000679", - "node_attrs": { - "div": 561, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-07-18" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "NY-NYCPHL-000679" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ419061" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C60620T", - "G87142A", - "T133099-", - "T150544-", - "A150545-", - "T150546-", - "G150547-", - "A150548-", - "A150549-", - "G150550-", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558A", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T" - ], - "OPG080": [ - "D467N" - ], - "OPG109": [ - "S769L" - ] - }, - "labels": { - "aa": "OPG080: D467N; OPG109: S769L" - } - } - } - ] - }, - { - "name": "NODE_0000220", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G50034A", - "G74200A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150566A", - "-150567T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179191A", - "-179192T", - "-179193T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "-196603A" - ], - "OPG069": [ - "E17K" - ], - "OPG094": [ - "D141N" - ] - }, - "labels": { - "aa": "OPG069: E17K; OPG094: D141N" - } - }, - "children": [ - { - "name": "9000396", - "node_attrs": { - "div": 559, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "9000396" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536774" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150563A", - "-150564T", - "-150565G" - ] - } - } - }, - { - "name": "NY-NYCPHL-001141", - "node_attrs": { - "div": 560, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-06-28" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "NY-NYCPHL-001141" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468598" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A31053G", - "A150566T", - "T150567A", - "A196715G" - ], - "OPG047": [ - "C48R" - ] - }, - "labels": { - "aa": "OPG047: C48R" - } - } - } - ] - }, - { - "name": "NODE_0000221", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C14077T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179191A", - "-179192T", - "-179193T" - ] - } - }, - "children": [ - { - "name": "MPXV_UK_2022_9000093", - "node_attrs": { - "div": 560, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-05-30" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000093" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205084" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C4529T", - "G155585A", - "G192681A" - ], - "OPG003": [ - "D27N" - ] - }, - "labels": { - "aa": "OPG003: D27N" - } - } - }, - { - "name": "MPX_cmjxZM_9000205", - "node_attrs": { - "div": 558, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPX_cmjxZM_9000205" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415186" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPX_K1dQNt_9000225", - "node_attrs": { - "div": 559, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPX_K1dQNt_9000225" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415201" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G147799A" - ], - "OPG172": [ - "A125T" - ] - }, - "labels": { - "aa": "OPG172: A125T" - } - } - } - ] - }, - { - "name": "NODE_0000222", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C148771T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-" - ], - "OPG174": [ - "D209N" - ] - }, - "labels": { - "aa": "OPG174: D209N" - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/ON/RKI701", - "node_attrs": { - "div": 559, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI701" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ417834" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C11747-", - "C126926T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG023": [ - "G385X", - "*661X" - ], - "OPG148": [ - "A314V" - ] - }, - "labels": { - "aa": "OPG023: G385X, *661X; OPG148: A314V" - } - } - }, - { - "name": "NODE_0000223", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G114316A" - ], - "OPG133": [ - "H461Y" - ] - }, - "labels": { - "aa": "OPG133: H461Y" - } - }, - "children": [ - { - "name": "MPXV/UZ_REGA_197/Belgium/2022", - "node_attrs": { - "div": 563, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-08-03" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_197/Belgium/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR087006" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C12637T", - "G53377A", - "T133099-", - "C178569T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "C182707T" - ], - "OPG210": [ - "S451F" - ] - }, - "labels": { - "aa": "OPG210: S451F" - } - } - }, - { - "name": "NODE_0000224", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G152437A" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI631", - "node_attrs": { - "div": 561, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-10-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI631" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ159026" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150547A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "G187677A" - ] - } - } - }, - { - "name": "INMI-19442022", - "node_attrs": { - "div": 560, - "author": { - "author": "Rueca,M., Tucci,F.G., Mazzotta,V., Gramigna,G., Gruber,C.E.M., Fabeni,L., Giombini,E., Matusali,G., Pinnetti,C., Mariano,A., Butera,O., Specchiarello,E., Mondi,A., Lanini,S., Carletti,F., Girardi,E., Vaia,F., Nicastri,E., Antinori,A., Maggi,F.", - "value": "Rueca,M., Tucci,F.G., Mazzotta,V., Gramigna,G., Gruber,C.E.M., Fabeni,L., Giombini,E., Matusali,G., Pinnetti,C., Mariano,A., Butera,O., Specchiarello,E., Mondi,A., Lanini,S., Carletti,F., Girardi,E., Vaia,F., Nicastri,E., Antinori,A., Maggi,F." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute for Infectious Diseases \"L. Spallanzani\" - IRCCS, Laboratory of Virology" - }, - "date": { - "value": "2022-09-14" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "INMI-19442022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ627928" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Italy" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A586-", - "A587-", - "A588-", - "-594T", - "A196599-", - "C196600-", - "-196602A" - ] - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000225", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G42504A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A196604-" - ] - } - }, - "children": [ - { - "name": "PatientMPXV", - "node_attrs": { - "div": 559, - "author": { - "author": "Seang,S., Burrel,S., Todesco,E., Leducq,V., Monsel,G., Le Pluart,D., Cordevant,C., Pourcher,V., Palich,R., Charpentier,C.", - "value": "Seang,S., Burrel,S., Todesco,E., Leducq,V., Monsel,G., Le Pluart,D., Cordevant,C., Pourcher,V., Palich,R., Charpentier,C." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "APHP Pitie Salpetriere SU, Virology" - }, - "date": { - "value": "2022-06-10" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "PatientMPXV" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP204840" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-593T", - "-594T", - "-595T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "G163250A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "A196605-", - "A196606-" - ] - } - } - }, - { - "name": "Monkeypox/PT0189/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-06-27" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "Monkeypox/PT0189/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP324503" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "G149478-", - "G186537A", - "-196603A", - "-196604A" - ], - "OPG175": [ - "G13X", - "*126X" - ], - "OPG210": [ - "E1728K" - ] - }, - "labels": { - "aa": "OPG175: G13X, *126X; OPG210: E1728K" - } - } - }, - { - "name": "Monkeypox/PT0479/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "Monkeypox/PT0479/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555558" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C134850T", - "C159741T" - ] - } - } - }, - { - "name": "NODE_0000226", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G74267A", - "C115870T" - ], - "OPG094": [ - "R163Q" - ] - }, - "labels": { - "aa": "OPG094: R163Q" - } - }, - "children": [ - { - "name": "MPX/PT0086/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-07-21" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPX/PT0086/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP245337" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000227", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "C5292T", - "G191918A" - ], - "NBT03_gp175": [ - "D289N" - ], - "OPG015": [ - "D289N" - ] - }, - "labels": { - "aa": "NBT03_gp175: D289N; OPG015: D289N" - } - }, - "children": [ - { - "name": "Monkeypox/PT0179/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-06-30" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "Monkeypox/PT0179/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP324494" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "Monkeypox/PT0493/2022", - "node_attrs": { - "div": 565, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-11" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "Monkeypox/PT0493/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555568" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-596T", - "G11924A", - "G125379A", - "A161784T", - "G176342A", - "-196604A" - ], - "OPG023": [ - "S326L" - ], - "OPG145": [ - "R478K" - ] - }, - "labels": { - "aa": "OPG023: S326L; OPG145: R478K" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000228", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C57173T", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - }, - "children": [ - { - "name": "PrEV_case_2", - "node_attrs": { - "div": 565, - "author": { - "author": "Berens-Riha,N., De Block,T., Rutgers,J., Van Gestel,L., Hens,M., Kenyon,C., Soentjens,P., Van Griensven,J., Brosius,I., Arien,K., Van Esbroeck,M., Rezende,A.M., Vercauteren,K.", - "value": "Berens-Riha,N., De Block,T., Rutgers,J., Van Gestel,L., Hens,M., Kenyon,C., Soentjens,P., Van Griensven,J., Brosius,I., Arien,K., Van Esbroeck,M., Rezende,A.M., Vercauteren,K." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "date": { - "value": "2022-10-02" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "PrEV_case_2" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP727822" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T348-", - "G349-", - "G350-", - "A351-", - "T352-", - "T353-", - "C11401T", - "C33964T", - "C36267T", - "G110285A", - "T133099-", - "C144366T", - "A174924T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "G180608A", - "A188349-", - "G195316A" - ], - "OPG052": [ - "R11Q" - ], - "OPG055": [ - "D273N" - ], - "OPG209": [ - "E31K" - ] - }, - "labels": { - "aa": "OPG052: R11Q; OPG055: D273N; OPG209: E31K" - } - } - }, - { - "name": "NODE_0000229", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C142797T", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T" - ], - "OPG164": [ - "S7L" - ] - }, - "labels": { - "aa": "OPG164: S7L" - } - }, - "children": [ - { - "name": "MpxV/human/CAN/UN-NML-4112/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Griffiths,E., Jolly,G., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N.", - "value": "Duggan,A., Hole,D., Yadav,C., Knox,N., Tyler,A., Haidl,E., Chapel,M., Domselaar,G.V., Graham,M., Audet,J., Fernando,L., Antonation,K., Safronetz,D., Hagan,M., Peters,G., Go,A., Laminman,V., Kaplen,B., Leung,A., Griffiths,E., Jolly,G., Eshaghi,A., Gubbay,J.B., Hasso,M., Marchand-Austin,A., Olsha,R., Patel,S.N." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "National Microbiology Laboratory, Public Health Agency of Canada" - }, - "date": { - "value": "2022-06-30" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MpxV/human/CAN/UN-NML-4112/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP279036" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Canada" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00361/2022", - "node_attrs": { - "div": 565, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2022-10-31" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00361/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP920699" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G105325A", - "C108658T", - "G111379A", - "C149889T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G165395A", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "G184244A" - ], - "OPG124": [ - "S215F" - ], - "OPG130": [ - "S175L" - ], - "OPG190": [ - "E92K" - ] - }, - "labels": { - "aa": "OPG124: S215F; OPG130: S175L; OPG190: E92K" - } - } - }, - { - "name": "MPXV_USA_2022_LA0006", - "node_attrs": { - "div": 560, - "author": { - "author": "Gigante,C., Haydel,D., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Salinas,A., Li,Y.", - "value": "Gigante,C., Haydel,D., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Salinas,A., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV_USA_2022_LA0006" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ702776" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "A136513-", - "T136514-", - "C136515-", - "G148615A", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "A196604-" - ], - "OPG153": [ - "D385-" - ], - "OPG174": [ - "L261F" - ] - }, - "labels": { - "aa": "OPG153: D385-; OPG174: L261F" - } - } - }, - { - "name": "MPXV_USA_2022_NC0003", - "node_attrs": { - "div": 560, - "author": { - "author": "Li,C.M.", - "value": "Li,C.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-12-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV_USA_2022_NC0003" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR209323" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G62268A", - "A136513-", - "T136514-", - "C136515-", - "A196604-" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "NODE_0000230", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C96914T", - "G158254A" - ], - "OPG117": [ - "S289L" - ] - }, - "labels": { - "aa": "OPG117: S289L" - } - }, - "children": [ - { - "name": "MPXV_USA_2022_KS0006", - "node_attrs": { - "div": 561, - "author": { - "author": "Gigante,C., Bradley,A., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Anderson,J., Li,Y.", - "value": "Gigante,C., Bradley,A., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Anderson,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV_USA_2022_KS0006" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ721922" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Human/USA/CA-LACPHL-MA00486/2023", - "node_attrs": { - "div": 567, - "author": { - "author": "Hemarajata,P., Green,N.M., Garrigues,J.M.", - "value": "Hemarajata,P., Green,N.M., Garrigues,J.M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health" - }, - "date": { - "value": "2023-02-18" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV/Human/USA/CA-LACPHL-MA00486/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ918697" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C55036T", - "G73789A", - "C136435T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C166803T", - "C170381T", - "G178559A", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "NBT03_gp052": [ - "E36K" - ], - "OPG094": [ - "G4R" - ], - "OPG192": [ - "P25S" - ], - "OPG198": [ - "S115L" - ] - }, - "labels": { - "aa": "NBT03_gp052: E36K; OPG094: G4R; OPG192: P25S; OPG198: S115L" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000159", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G63147A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179163-", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - }, - "children": [ - { - "name": "MPXV/Germany/2022/RKI396", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI396" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP523999" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A136513-", - "T136514-", - "C136515-", - "-196603A" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "NODE_0000160", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G10224A", - "G129761A", - "T143625A", - "C177847T", - "-196603A" - ], - "OPG021": [ - "R213Q" - ], - "OPG151": [ - "D280N" - ], - "OPG165": [ - "I37N" - ], - "OPG205": [ - "S731L" - ] - }, - "labels": { - "aa": "OPG021: R213Q; OPG151: D280N; OPG165: I37N; OPG205: S731L" - } - }, - "children": [ - { - "name": "NICD-SVPL223", - "node_attrs": { - "div": 562, - "author": { - "author": "Chan,W.Y., Mtshali,S., Grobbelaar,A., Moolla,N., Mohale,T., Lowe,M., Du Plessis,M., Ismail,A., Weyer,J.", - "value": "Chan,W.Y., Mtshali,S., Grobbelaar,A., Moolla,N., Mohale,T., Lowe,M., Du Plessis,M., Ismail,A., Weyer,J." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "National Institute for Communicable Disease, Sequencing Core Facility" - }, - "date": { - "value": "2022-06-20" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "NICD-SVPL223" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON918611" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "South Africa" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T" - ] - } - } - }, - { - "name": "NICD-SVPL232", - "node_attrs": { - "div": 562, - "author": { - "author": "Chan,W.Y., Mtshali,P.S., Grobbelaar,A., Moolla,N., Mohale,T., Lowe,M., Du Plessis,M., Ismail,A., Weyer,J.", - "value": "Chan,W.Y., Mtshali,P.S., Grobbelaar,A., Moolla,N., Mohale,T., Lowe,M., Du Plessis,M., Ismail,A., Weyer,J." - }, - "region": { - "value": "Africa" - }, - "institution": { - "value": "National Institute for Communicable Disease, Sequencing core facility" - }, - "date": { - "value": "2022-06-24" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "NICD-SVPL232" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON927248" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "South Africa" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A196603C" - ] - } - } - } - ] - }, - { - "name": "NODE_0000161", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C15004T", - "C101845T", - "G177780A", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C" - ], - "OPG121": [ - "S19F" - ], - "OPG205": [ - "E709K" - ] - }, - "labels": { - "aa": "OPG121: S19F; OPG205: E709K" - } - }, - "children": [ - { - "name": "MPX_vSkiJH_9000281", - "node_attrs": { - "div": 562, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPX_vSkiJH_9000281" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415243" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "C155483T" - ] - } - } - }, - { - "name": "9000418", - "node_attrs": { - "div": 561, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "9000418" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536792" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - } - ] - }, - { - "name": "NODE_0000162", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C70780T", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C" - ] - } - }, - "children": [ - { - "name": "MPXV_UK_2022_9000106", - "node_attrs": { - "div": 559, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-06-14" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000106" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205094" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Germany/2022/RKI240", - "node_attrs": { - "div": 562, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Jessen,H., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI240" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP215225" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T25644C", - "C32909T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "C190668T" - ], - "NBT03_gp174": [ - "R87*" - ] - }, - "labels": { - "aa": "NBT03_gp174: R87*" - } - } - }, - { - "name": "9000289", - "node_attrs": { - "div": 560, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "9000289" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP413714" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G16608-", - "T16609-", - "C16610-", - "A16611G" - ], - "OPG029": [ - "D154-" - ] - }, - "labels": { - "aa": "OPG029: D154-" - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000231", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G120241A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C179172-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG137": [ - "D214N" - ] - }, - "labels": { - "aa": "OPG137: D214N" - } - }, - "children": [ - { - "name": "Monkeypox/MX-UANL001/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Galan-Huerta,K.A., Paz-Infanzon,M., Ruiz-Higareda,A.F., Nuzzolo-Shihadeh,L., Camacho-Ortiz,A., Bocanegra-Ibarias,P., Rivas-Estilla,A.M., Zacarias-Villarreal,D., Yamallel-Ortega,L.A., Guerrero-Putz,M.D., Ocampo-Candiani,J.", - "value": "Galan-Huerta,K.A., Paz-Infanzon,M., Ruiz-Higareda,A.F., Nuzzolo-Shihadeh,L., Camacho-Ortiz,A., Bocanegra-Ibarias,P., Rivas-Estilla,A.M., Zacarias-Villarreal,D., Yamallel-Ortega,L.A., Guerrero-Putz,M.D., Ocampo-Candiani,J." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Universidad Autonoma de Nuevo Leon - Facultad de Medicina, Centro de Investigacion e Innovacion en Virologia Medica" - }, - "date": { - "value": "2022-06-28" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "Monkeypox/MX-UANL001/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON911481" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Mexico" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G57088A", - "C127530T", - "T133095-", - "T133096-", - "T133097-", - "T133098-", - "T133099-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "T168120C", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "-196601A", - "-196602A", - "-196603A" - ], - "OPG074": [ - "S13L" - ], - "OPG149": [ - "S112L" - ], - "OPG193": [ - "F263L" - ] - }, - "labels": { - "aa": "OPG074: S13L; OPG149: S112L; OPG193: F263L" - } - } - }, - { - "name": "MPX/PT0058/2022", - "node_attrs": { - "div": 558, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-07-28" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPX/PT0058/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP245314" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C179163-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI357", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI357" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP484678" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C179163-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI537", - "node_attrs": { - "div": 560, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI537" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP715817" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C28048T", - "C124534T", - "C179163-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI544", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI544" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP715824" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI877", - "node_attrs": { - "div": 558, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI877" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773496" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G150550-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T" - ] - } - } - }, - { - "name": "NODE_0000232", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C125660T", - "T133098-", - "T133099-", - "A136513-", - "T136514-", - "C136515-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG147": [ - "D110N" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG147: D110N; OPG153: D385-" - } - }, - "children": [ - { - "name": "NY-NYCPHL-000891", - "node_attrs": { - "div": 559, - "author": { - "author": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Amin,H.S., Clabby,T.T., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-07-08" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "NY-NYCPHL-000891" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468681" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NY-NYCPHL-000243", - "node_attrs": { - "div": 561, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-08-02" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.7" - }, - "strain_original": { - "value": "NY-NYCPHL-000243" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469058" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C96938T", - "T133096-", - "T133097-", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "C155515T" - ], - "OPG117": [ - "S297L" - ] - }, - "labels": { - "aa": "OPG117: S297L" - } - } - } - ] - } - ] - } - ] - }, - { - "name": "NODE_0000265", - "node_attrs": { - "div": 557, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179173A", - "-179174T", - "-179175T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "G190660A" - ], - "NBT03_gp174": [ - "R84K" - ] - }, - "labels": { - "aa": "NBT03_gp174: R84K", - "clade": "B.1.3" - } - }, - "children": [ - { - "name": "MPxV/Prague_001/2022/flye_medaka", - "node_attrs": { - "div": 557, - "author": { - "author": "Chmel,M., Pajer,P., Nagy,A., Zlamal,M., Jirincova,H., Dresler,J., Bartos,O.", - "value": "Chmel,M., Pajer,P., Nagy,A., Zlamal,M., Jirincova,H., Dresler,J., Bartos,O." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Military Heatlh Institute, Military Heatlh Institute in Prague" - }, - "date": { - "value": "2022-04-28" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPxV/Prague_001/2022/flye_medaka" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON983168" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Czech Republic" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T80841-" - ], - "OPG104": [ - "N60X", - "*134X" - ] - }, - "labels": { - "aa": "OPG104: N60X, *134X" - } - } - }, - { - "name": "MPXV_USA_2022_CA006", - "node_attrs": { - "div": 558, - "author": { - "author": "Gigante,C., Ventura,J., Seabolt,M.H., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nash,J., Sheth,M., Li,Y.", - "value": "Gigante,C., Ventura,J., Seabolt,M.H., Zhao,H., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nash,J., Sheth,M., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV_USA_2022_CA006" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP150924" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-596T", - "C17752T" - ], - "OPG030": [ - "E28K" - ] - }, - "labels": { - "aa": "OPG030: E28K" - } - } - }, - { - "name": "9000403", - "node_attrs": { - "div": 562, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "9000403" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536779" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C17196T", - "C39898T", - "A62034-", - "C148933T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G171318A", - "C175241T", - "A196604-" - ], - "OPG057": [ - "D100N" - ], - "OPG174": [ - "E155K" - ], - "OPG199": [ - "E111K" - ], - "OPG204": [ - "S237L" - ] - }, - "labels": { - "aa": "OPG057: D100N; OPG174: E155K; OPG199: E111K; OPG204: S237L" - } - } - }, - { - "name": "9000432", - "node_attrs": { - "div": 558, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "9000432" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536804" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C6423A", - "C135775T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "T190786-", - "A196604-" - ], - "NBT03_gp174": [ - "I126X", - "*177X" - ] - }, - "labels": { - "aa": "NBT03_gp174: I126X, *177X" - } - } - }, - { - "name": "PrEV_case_1", - "node_attrs": { - "div": 557, - "author": { - "author": "Berens-Riha,N., De Block,T., Rutgers,J., Van Gestel,L., Hens,M., Kenyon,C., Soentjens,P., Van Griensven,J., Brosius,I., Arien,K., Van Esbroeck,M., Rezende,A.M., Vercauteren,K.", - "value": "Berens-Riha,N., De Block,T., Rutgers,J., Van Gestel,L., Hens,M., Kenyon,C., Soentjens,P., Van Griensven,J., Brosius,I., Arien,K., Van Esbroeck,M., Rezende,A.M., Vercauteren,K." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "date": { - "value": "2022-08-27" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "PrEV_case_1" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP727821" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133094-", - "T133095-", - "T133096-", - "T133097-", - "T133098-", - "T133099-", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "G179020-", - "T179021-", - "C179022-", - "G179023-", - "A179024-", - "G179025-", - "T179026-", - "A179027-", - "T179028-", - "G179029-", - "A179030-", - "A179031-", - "T179032-", - "A179033-", - "C179034-", - "G179035-", - "G179036-", - "A179037-", - "G179038-", - "T179039-", - "A179040-", - "C179041-", - "A179042-", - "A179043-", - "A179044-", - "C179045-", - "A179046-", - "T179047-", - "A179048-", - "A179049-", - "A179050-", - "C179051-" - ] - } - } - }, - { - "name": "NY-NYCPHL-000118", - "node_attrs": { - "div": 560, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-06-22" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "NY-NYCPHL-000118" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ504398" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C2315T", - "C102077T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150566A", - "-150567T", - "C170204T", - "G194895A" - ], - "OPG002": [ - "G146E" - ], - "OPG198": [ - "S56F" - ] - }, - "labels": { - "aa": "OPG002: G146E; OPG198: S56F" - } - } - }, - { - "name": "NODE_0000266", - "node_attrs": { - "div": 558, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C64426T", - "A179209-", - "T179210-", - "T179211-", - "A179212-", - "T179213-", - "A179214-", - "T179215-", - "A179216-", - "C179217-", - "A179218-", - "T179219-", - "T179220-", - "A179221-", - "T179222-", - "A179223-", - "T179224-", - "A179225-", - "C179226-" - ] - } - }, - "children": [ - { - "name": "MPXV/human/Taiwan/110-525030/2023", - "node_attrs": { - "div": 565, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "date": { - "value": "2023-03-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/human/Taiwan/110-525030/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ721953" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Taiwan" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T597-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C166940T", - "T177665A", - "A177666T", - "A177667T", - "G178104T", - "G178290T", - "T178629A", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "G196412A" - ], - "OPG205": [ - "N670K", - "N671F" - ] - }, - "labels": { - "aa": "OPG205: N670K, N671F" - } - } - }, - { - "name": "NODE_0000267", - "node_attrs": { - "div": 559, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-596T", - "G55133A" - ], - "OPG074": [ - "R665C" - ] - }, - "labels": { - "aa": "OPG074: R665C" - } - }, - "children": [ - { - "name": "MPXV_FR_HCL0001_2022", - "node_attrs": { - "div": 560, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Virology, GENomique EPIdemiologique das maladies Infectieuses, France" - }, - "date": { - "value": "2022-05-22" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV_FR_HCL0001_2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON622722" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "France" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C109627A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG129": [ - "A460S" - ] - }, - "labels": { - "aa": "OPG129: A460S" - } - } - }, - { - "name": "MPXV_SI2022_S3", - "node_attrs": { - "div": 559, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV_SI2022_S3" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON754984" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A133-", - "-595T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI050", - "node_attrs": { - "div": 560, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI050" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON755256" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A36620C", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG055": [ - "V155G" - ] - }, - "labels": { - "aa": "OPG055: V155G" - } - } - }, - { - "name": "MPXV/Spain/HUNSC_ITER_0001a/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Alcoba-Florez,J., Munoz-Barrera,A., Ciuffreda,L., Rodriguez-Perez,H., Rubio-Rodriguez,L.A., Gil-Campesino,H., Garcia-Martinez de Artola,D., Inigo-Campos,A., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C.", - "value": "Alcoba-Florez,J., Munoz-Barrera,A., Ciuffreda,L., Rodriguez-Perez,H., Rubio-Rodriguez,L.A., Gil-Campesino,H., Garcia-Martinez de Artola,D., Inigo-Campos,A., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division" - }, - "date": { - "value": "2022-05-31" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/Spain/HUNSC_ITER_0001a/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON782054" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G50337A", - "A122238T", - "-133164C", - "-133165A", - "-133166A", - "-133167T", - "-133168C", - "-133169T", - "-133170T", - "-133171T", - "-133172C", - "-133173T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A169759G", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A193392G", - "T193688C", - "T194099C", - "T194619C", - "T195948C", - "-196603A" - ], - "OPG001": [ - "L105S" - ], - "OPG002": [ - "F54S" - ], - "OPG003": [ - "N264D" - ], - "OPG069": [ - "G118R" - ], - "OPG143": [ - "S360T" - ] - }, - "labels": { - "aa": "OPG001: L105S; OPG002: F54S; OPG003: N264D; OPG069: G118R; OPG143: S360T" - } - } - }, - { - "name": "MPXV/Spain/HUNSC_ITER_0001b/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Alcoba-Florez,J., Munoz-Barrera,A., Ciuffreda,L., Rodriguez-Perez,H., Rubio-Rodriguez,L.A., Gil-Campesino,H., Garcia-Martinez de Artola,D., Inigo-Campos,A., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C.", - "value": "Alcoba-Florez,J., Munoz-Barrera,A., Ciuffreda,L., Rodriguez-Perez,H., Rubio-Rodriguez,L.A., Gil-Campesino,H., Garcia-Martinez de Artola,D., Inigo-Campos,A., Diez-Gil,O., Gonzalez-Montelongo,R., Valenzuela-Fernandez,A., Lorenzo-Salazar,J.M., Flores,C." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division" - }, - "date": { - "value": "2022-05-31" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/Spain/HUNSC_ITER_0001b/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON782055" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Spain" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A48265T", - "C48296G", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG068": [ - "D22V" - ] - }, - "labels": { - "aa": "OPG068: D22V" - } - } - }, - { - "name": "hMpxV/Switzerland/ZH-UZH-IMV-3ba6449f/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Kufner,V., Ziltener,G., Zaheri,M., Schmutz,S., Audige,A., Bernasconi,O., Steiner,K., Huder,J., Shah,C., Capaul,R., Bloemberg,G., Boeni,J., Huber,M., Trkola,A.", - "value": "Kufner,V., Ziltener,G., Zaheri,M., Schmutz,S., Audige,A., Bernasconi,O., Steiner,K., Huder,J., Shah,C., Capaul,R., Bloemberg,G., Boeni,J., Huber,M., Trkola,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Zurich, Institute of Medical Virology" - }, - "date": { - "value": "2022-06-01" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "hMpxV/Switzerland/ZH-UZH-IMV-3ba6449f/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON792320" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Switzerland" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G159376A" - ], - "OPG185": [ - "D154N" - ] - }, - "labels": { - "aa": "OPG185: D154N" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI079", - "node_attrs": { - "div": 560, - "author": { - "author": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Uddin,S., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI079" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON853661" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C15947T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG027": [ - "R144K" - ] - }, - "labels": { - "aa": "OPG027: R144K" - } - } - }, - { - "name": "MPXV_UK_2022_9000061", - "node_attrs": { - "div": 559, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-05-27" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000061" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205067" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "-196603A" - ] - } - } - }, - { - "name": "MPXV_UK_2022_9000188", - "node_attrs": { - "div": 560, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-06-29" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV_UK_2022_9000188" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP205133" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C142545T", - "-196603A" - ], - "OPG163": [ - "S115F" - ] - }, - "labels": { - "aa": "OPG163: S115F" - } - } - }, - { - "name": "MPXV/Germany/2022/RKI288", - "node_attrs": { - "div": 561, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Friesen,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Friesen,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI288" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP270477" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C12960T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C174633T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI311", - "node_attrs": { - "div": 559, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Uddin,S., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI311" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP355570" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "A188349-" - ] - } - } - }, - { - "name": "MPX_7f1tnH_9000280", - "node_attrs": { - "div": 559, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPX_7f1tnH_9000280" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415242" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "A196604-" - ] - } - } - }, - { - "name": "MPX_z0MIuQ_9000282", - "node_attrs": { - "div": 559, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPX_z0MIuQ_9000282" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP415244" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "A196604-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/RKI392", - "node_attrs": { - "div": 562, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/Germany/2022/RKI392" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP523994" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G36659A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G174642A", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "C190444T" - ], - "NBT03_gp174": [ - "S12L" - ], - "OPG055": [ - "A142V" - ], - "OPG204": [ - "M37I" - ] - }, - "labels": { - "aa": "NBT03_gp174: S12L; OPG055: A142V; OPG204: M37I" - } - } - }, - { - "name": "9000409", - "node_attrs": { - "div": 562, - "author": { - "author": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M.", - "value": "Groves,N., Osman,K.L., Lewandowski,K.S., Carter,D.P., Pullan,S.T., Myers,R., Vipond,R., Chand,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "UKHSA, Research and Evaluation" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "9000409" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP536785" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "United Kingdom" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594T", - "-595T", - "G101152A", - "G124855T", - "G141131A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "-196602A", - "-196603A" - ], - "OPG145": [ - "E303D" - ] - }, - "labels": { - "aa": "OPG145: E303D" - } - } - }, - { - "name": "Monkeypox/PT0514/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-16" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "Monkeypox/PT0514/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555585" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A136513-", - "T136514-", - "C136515-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "Monkeypox/PT0524/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-08-18" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "Monkeypox/PT0524/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555595" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A136513-", - "T136514-", - "C136515-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG153": [ - "D385-" - ] - }, - "labels": { - "aa": "OPG153: D385-" - } - } - }, - { - "name": "Monkeypox/PT0562/2022", - "node_attrs": { - "div": 560, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-09-01" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "Monkeypox/PT0562/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555633" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A136513-", - "T136514-", - "C136515-", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C168066T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG153": [ - "D385-" - ], - "OPG193": [ - "Q245*" - ] - }, - "labels": { - "aa": "OPG153: D385-; OPG193: Q245*" - } - } - }, - { - "name": "Slovenia-MPXV-20-2022", - "node_attrs": { - "div": 565, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "Slovenia-MPXV-20-2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605562" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-594A", - "-595T", - "A29748T", - "G72609A", - "G72610T", - "G72611T", - "T72614A", - "A72617C", - "C72618-", - "G72619-", - "T72620-", - "A72621-", - "T72622-" - ], - "OPG047": [ - "*483K" - ], - "OPG092": [ - "N109X", - "T110-", - "C111G", - "K112X", - "P113N", - "*372X" - ] - }, - "labels": { - "aa": "OPG047: *483K; OPG092: N109X, T110-, C111G, K112X, P113N, *372X" - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI451", - "node_attrs": { - "div": 559, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI451" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP615322" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T" - ] - } - } - }, - { - "name": "MPXV_USA_2022_IA0002", - "node_attrs": { - "div": 559, - "author": { - "author": "Gigante,C., Hottel,W., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nelson,M., Li,Y.", - "value": "Gigante,C., Hottel,W., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Sheth,M., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Nelson,M., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV_USA_2022_IA0002" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ054221" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A196604-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI669", - "node_attrs": { - "div": 559, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI669" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ274888" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A152668-", - "T152680-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI670", - "node_attrs": { - "div": 559, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-05-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI670" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ274889" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A152668-", - "T152680-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T" - ] - } - } - }, - { - "name": "NY-NYCPHL-000370", - "node_attrs": { - "div": 561, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-08-15" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "NY-NYCPHL-000370" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468489" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G84360A", - "G151272A", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG105": [ - "E1079K" - ] - }, - "labels": { - "aa": "OPG105: E1079K" - } - } - }, - { - "name": "NY-NYCPHL-000463", - "node_attrs": { - "div": 561, - "author": { - "author": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Clabby,T.T., Amin,H.S., Wang,J.C., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-07-22" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "NY-NYCPHL-000463" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ469188" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C111745T", - "C115323T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150567T", - "A173274-", - "T173275-", - "A173276-", - "T173277-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG130": [ - "R53Q" - ], - "OPG133": [ - "C125Y" - ] - }, - "labels": { - "aa": "OPG130: R53Q; OPG133: C125Y" - } - } - }, - { - "name": "MPXV_USA_2022_NY0008", - "node_attrs": { - "div": 559, - "author": { - "author": "Gigante,C., Ruiz,V., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Wang,J., Li,Y.", - "value": "Gigante,C., Ruiz,V., Zhao,H., Batra,D., Hetrick,E., Howard,D., Kovar,L., Seabolt,M., Morrison,S., Desch,M., Knipe,K., Weigand,M., Cintron,R., Burgin,A., Burroughs,M., Lee,J., Wilkins,K., McCollum,A., Hutson,C., Davidson,W., Rao,A., Wang,J., Li,Y." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "CDC, DHCPP-PRB" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV_USA_2022_NY0008" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ557947" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI834", - "node_attrs": { - "div": 559, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI834" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773453" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T" - ] - } - } - }, - { - "name": "MPXV/Germany/2022/ON/RKI851", - "node_attrs": { - "div": 559, - "author": { - "author": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/Germany/2022/ON/RKI851" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ773470" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_80", - "node_attrs": { - "div": 560, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-08-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_80" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035686" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C22950T", - "T133098-", - "T133099-", - "C133161T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_109", - "node_attrs": { - "div": 559, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-10-28" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_109" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035715" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133099-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "T195509-", - "A195510-", - "A195511-" - ] - } - } - }, - { - "name": "RNA", - "node_attrs": { - "div": 561, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava" - }, - "date": { - "value": "2022-07-04" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "RNA" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OX248696" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovakia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T596-", - "G37250A", - "C138080T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-", - "A196604-" - ], - "OPG155": [ - "E138K" - ] - }, - "labels": { - "aa": "OPG155: E138K" - } - } - }, - { - "name": "MPX-37/Finland/2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Kant,R., Smura,T., Vauhkonen,H., Vapalahti,O.", - "value": "Kant,R., Smura,T., Vauhkonen,H., Vapalahti,O." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "University of Helsinki, Department of Virology, Faculty of Medicine" - }, - "date": { - "value": "2022-05-24" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPX-37/Finland/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON782021" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Finland" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "Slovenia-MPXV-08-2022", - "node_attrs": { - "div": 559, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "date": { - "value": "2022-06-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "Slovenia-MPXV-08-2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605551" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A27-", - "T153-", - "-595T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "NODE_0000268", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A27-", - "T153-", - "-595T", - "G167517A", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG193": [ - "E62K" - ] - }, - "labels": { - "aa": "OPG193: E62K" - } - }, - "children": [ - { - "name": "SLO", - "node_attrs": { - "div": 560, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Skubic,C., Rozman,D., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Skubic,C., Rozman,D., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia" - }, - "date": { - "value": "2022-05-23" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "SLO" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON609725" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV_SI2022_S1_VEROE6", - "node_attrs": { - "div": 560, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "date": { - "value": "2022-05-23" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV_SI2022_S1_VEROE6" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON754987" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - }, - { - "name": "NODE_0000270", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C133161T", - "C157632T" - ] - } - }, - "children": [ - { - "name": "Monkeypox/PT0376/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2022-07-07" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "Monkeypox/PT0376/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP555472" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "G159243A", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_165/Belgium/2022", - "node_attrs": { - "div": 561, - "author": { - "author": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P.", - "value": "Vanmechelen,B., Wawina-Bokalanga,T., Logist,A.-S., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-07-27" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_165/Belgium/2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR086974" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G41336A", - "T133099-", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - } - ] - }, - { - "name": "NODE_0000271", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G85581A", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG107": [ - "V24I" - ] - }, - "labels": { - "aa": "OPG107: V24I" - } - }, - "children": [ - { - "name": "NY-NYCPHL-000626", - "node_attrs": { - "div": 563, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-09-28" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "NY-NYCPHL-000626" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ468721" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T39396C", - "G66009A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150567T", - "G188294A" - ], - "OPG057": [ - "N267S" - ], - "OPG084": [ - "D430N" - ] - }, - "labels": { - "aa": "OPG057: N267S; OPG084: D430N" - } - } - }, - { - "name": "NY-NYCPHL-000393", - "node_attrs": { - "div": 565, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2022-08-19" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "NY-NYCPHL-000393" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ504426" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G1081T", - "G52340A", - "C84063T", - "C110983T", - "G127179A", - "G134683A", - "C196129A" - ], - "OPG071": [ - "S700L" - ], - "OPG129": [ - "D8N" - ] - }, - "labels": { - "aa": "OPG071: S700L; OPG129: D8N" - } - } - } - ] - }, - { - "name": "NODE_0000272", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133099-", - "T168120C", - "T179026-", - "A179027-", - "T179028-", - "G179029-", - "A179030-", - "A179031-", - "T179032-", - "A179033-", - "C179034-", - "G179035-", - "G179036-", - "A179037-", - "G179038-", - "T179039-", - "A179040-", - "C179041-", - "A179042-", - "A179043-", - "A179044-", - "C179045-", - "A179046-", - "T179047-", - "A179048-", - "A179049-", - "A179050-", - "C179051-", - "T179052-", - "G179053-", - "A179054-", - "A179055-", - "G179056-", - "T179057-" - ], - "OPG193": [ - "F263L" - ] - }, - "labels": { - "aa": "OPG193: F263L" - } - }, - "children": [ - { - "name": "MPXV/ITM_pt_31/Belgium/27-May-2022", - "node_attrs": { - "div": 560, - "author": { - "author": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., Van den Bossche,D., Florence,E., Rezende,A.M., Vercauteren,K., Van Esbroeck,M.", - "value": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., Van den Bossche,D., Florence,E., Rezende,A.M., Vercauteren,K., Van Esbroeck,M." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "date": { - "value": "2022-05-27" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/ITM_pt_31/Belgium/27-May-2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "ON950045" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G140101-", - "T140102-", - "T140103-", - "A140104-", - "A140105-", - "T140106-", - "A140107-", - "A140108-", - "C140109-", - "A140110-", - "A140111-", - "T140112-", - "T140113-", - "A140114-", - "T140115-", - "A140116-", - "A140117-", - "C140118-", - "A140119-", - "A140120-", - "T140121-", - "T140122-", - "A140123-", - "T140124-", - "A140125-", - "A140126-", - "C140127-", - "A140128-", - "A140129-", - "T140130-", - "T140131-", - "A140132-", - "T140133-", - "A140134-", - "A140135-", - "C140136-", - "A140137-", - "A140138-", - "T140139-", - "T140140-", - "A140141-", - "T140142-", - "A140143-", - "A140144-", - "T140145-", - "T140146-", - "G140147-", - "T140148-", - "T140149-", - "A140150-", - "T140151-", - "A140152-", - "A140153-", - "T140154-", - "A140155-", - "A140156-", - "T140157-", - "T140158-", - "A140159-", - "T140160-", - "A140161-", - "A140162-", - "T140163-", - "T140164-", - "-196603A" - ], - "OPG159": [ - "V112-", - "N113-", - "N114-", - "N115-", - "Y116-", - "N117-", - "N118-", - "Y119-", - "N120-", - "N121-", - "Y122-", - "N123-", - "N124-", - "Y125-", - "N126-", - "C127-", - "Y128-", - "N129-", - "N130-", - "Y131-", - "N132-", - "C133X", - "*146X" - ] - }, - "labels": { - "aa": "OPG159: V112-, N113-, N114-, N115-, Y116-, N117-, N118-, Y119-, N120-, N121-, Y122-, N123-, N124-, Y125-, N126-, C127-, Y128-, N129-, N130-, Y131-, N132-, C133X, *146X" - } - } - }, - { - "name": "NODE_0000273", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C133161T", - "C157632T", - "T179058-", - "T179059-", - "A179060-", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-", - "A179077-", - "T179078-", - "A179079-", - "T179080-" - ] - } - }, - "children": [ - { - "name": "MPXV/ITM_pt_16/Belgium/10-Jun-2022", - "node_attrs": { - "div": 561, - "author": { - "author": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., den Bossche,D.V., Florence,E., Rezende,A.M., Vercauteren,K., Esbroeck,M.V., Bracke,S., Brosius,I., Soentjens,P.", - "value": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., den Bossche,D.V., Florence,E., Rezende,A.M., Vercauteren,K., Esbroeck,M.V., Bracke,S., Brosius,I., Soentjens,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "date": { - "value": "2022-06-10" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/ITM_pt_16/Belgium/10-Jun-2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP144212" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C146824T", - "G179020-", - "T179021-", - "C179022-", - "G179023-", - "A179024-", - "G179025-", - "T196998-" - ] - } - } - }, - { - "name": "MPXV/ITM_pt_25/Belgium/16-Jun-2022", - "node_attrs": { - "div": 561, - "author": { - "author": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., den Bossche,D.V., Florence,E., Rezende,A.M., Vercauteren,K., Esbroeck,M.V., Bracke,S., Brosius,I., Soentjens,P.", - "value": "De Baetselier,I., Van Dijck,C., Kenyon,C., Coppens,J., Smet,H., de Block,T., Coppens,S., Vanroye,F., Bugert,J., Girl,P., Liesenborghs,L., Selhorst,P., Arien,K., den Bossche,D.V., Florence,E., Rezende,A.M., Vercauteren,K., Esbroeck,M.V., Bracke,S., Brosius,I., Soentjens,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Tropica Medicine, Department of Clinical Sciences" - }, - "date": { - "value": "2022-06-16" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/ITM_pt_25/Belgium/16-Jun-2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP144214" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-133099T", - "-179026T", - "-179027A", - "-179028T", - "-179029G", - "-179030A", - "-179031A", - "-179032T", - "-179033A", - "-179034C", - "-179035G", - "-179036G", - "-179037A", - "-179038G", - "-179039T", - "-179040A", - "-179041C", - "-179042A", - "-179043A", - "-179044A", - "-179045C", - "-179046A", - "-179047T", - "-179048A" - ] - } - } - } - ] - } - ] - }, - { - "name": "NODE_0000274", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C8612T", - "C56018T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "G187156A" - ], - "OPG074": [ - "E370K" - ] - }, - "labels": { - "aa": "OPG074: E370K" - } - }, - "children": [ - { - "name": "Slovenia-MPXV-28-2022", - "node_attrs": { - "div": 562, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "date": { - "value": "2022-07-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "Slovenia-MPXV-28-2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605570" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "A192374T" - ] - } - } - }, - { - "name": "NODE_0000275", - "node_attrs": { - "div": 563, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G52232A" - ], - "OPG071": [ - "S736L" - ] - }, - "labels": { - "aa": "OPG071: S736L" - } - }, - "children": [ - { - "name": "Slovenia-MPXV-40-2022", - "node_attrs": { - "div": 563, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "Slovenia-MPXV-40-2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605581" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C126-" - ] - } - } - }, - { - "name": "Slovenia-MPXV-44-2022", - "node_attrs": { - "div": 563, - "author": { - "author": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T.", - "value": "Zakotnik,S., Vlaj,D., Suljic,A., Zorec,T.M., Korva,M., Poljak,M., Avsic Zupanc,T." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre" - }, - "date": { - "value": "2022-08-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "Slovenia-MPXV-44-2022" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OP605585" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Slovenia" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000276", - "node_attrs": { - "div": 570, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C19558T", - "G32277A", - "C35688T", - "G39140A", - "G55059A", - "G75512A", - "C110402T", - "C121161T", - "T150544-", - "A150545-", - "T150546-", - "G150547-", - "A150548-", - "A150549-", - "G150550-", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558A", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C170673T", - "C179542T", - "C189174T" - ], - "NBT03_gp052": [ - "S28L" - ], - "OPG034": [ - "E150K" - ], - "OPG049": [ - "S292L" - ], - "OPG095": [ - "R237K" - ], - "OPG139": [ - "A70T" - ] - }, - "labels": { - "aa": "NBT03_gp052: S28L; OPG034: E150K; OPG049: S292L; OPG095: R237K; OPG139: A70T" - } - }, - "children": [ - { - "name": "NY-NYCPHL-001190", - "node_attrs": { - "div": 570, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2023-01-11" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "NY-NYCPHL-001190" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ419090" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ] - } - } - }, - { - "name": "NY-NYCPHL-001191", - "node_attrs": { - "div": 572, - "author": { - "author": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S.", - "value": "Wang,J.C., Amin,H.S., Clabby,T.T., Taki,F., Su,M., Rahat,A., De La Cruz,N., Olsen,A., Thi,C., Silver,S., Akther,S., Chowdhury,M., Omoregie,E., Hughes,S." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "NYC Department of Health and Mental Hygiene, Public Health Laboratory" - }, - "date": { - "value": "2023-01-11" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "NY-NYCPHL-001191" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ419091" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C134545T", - "C138212T", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C" - ], - "OPG155": [ - "E94K" - ] - }, - "labels": { - "aa": "OPG155: E94K" - } - } - }, - { - "name": "B1221136", - "node_attrs": { - "div": 570, - "author": { - "author": "Miller,H., Bajwa,M.", - "value": "Miller,H., Bajwa,M." - }, - "region": { - "value": "North America" - }, - "institution": { - "value": "Delaware Public Health Lab, Sequencing/Bioinformatics" - }, - "date": { - "value": "2023-03-13" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "B1221136" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR134560" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "USA" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-150544T", - "-150545A", - "-150546T", - "-150547G", - "-150548A", - "-150549A", - "-150550G", - "-150551G", - "-150552A", - "A150558T", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ] - } - } - } - ] - }, - { - "name": "NODE_0000277", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G152776A", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG180": [ - "D29N" - ] - }, - "labels": { - "aa": "OPG180: D29N" - } - }, - "children": [ - { - "name": "MPXV/human/Taiwan/109-005210/2023", - "node_attrs": { - "div": 562, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "date": { - "value": "2023-02-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/human/Taiwan/109-005210/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ581854" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Taiwan" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T64426C", - "G158406A", - "T192403-", - "A192404-", - "G192405-", - "A192410-" - ] - } - } - }, - { - "name": "NODE_0000278", - "node_attrs": { - "div": 571, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C15969T", - "C17998T", - "G40610A", - "C43803T", - "C63879T", - "G70190A", - "G118289A", - "C147011T", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "C159532T", - "G161629A", - "C189427T" - ], - "OPG005": [ - "P77S" - ], - "OPG027": [ - "E137K" - ], - "OPG031": [ - "M277I" - ], - "OPG064": [ - "G699E" - ], - "OPG083": [ - "D280N" - ], - "OPG089": [ - "E109K" - ], - "OPG185": [ - "P206S" - ], - "OPG188": [ - "E12K" - ] - }, - "labels": { - "aa": "OPG005: P77S; OPG027: E137K; OPG031: M277I; OPG064: G699E; OPG083: D280N; OPG089: E109K; OPG185: P206S; OPG188: E12K" - } - }, - "children": [ - { - "name": "MPXV/Germany/2023/RKI718", - "node_attrs": { - "div": 571, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2023-01-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/Germany/2023/RKI718" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ451903" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/Germany/2023/RKI719", - "node_attrs": { - "div": 571, - "author": { - "author": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A.", - "value": "Brinkmann,A., Kohl,C., Pape,K., Schrick,L., Michel,J., Schaade,L., Nitsche,A." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses" - }, - "date": { - "value": "2023-01-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "B.1.3" - }, - "strain_original": { - "value": "MPXV/Germany/2023/RKI719" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ451904" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Germany" - } - }, - "branch_attrs": { - "mutations": {} - } - } - ] - } - ] - }, - { - "name": "NODE_0000279", - "node_attrs": { - "div": 560, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G105923A", - "-150551G", - "-150552A", - "-150553T", - "-150554A", - "-150555T", - "-150556G", - "-150557A", - "-150558T", - "-150559G", - "-150560G", - "-150561A", - "-150562T", - "-150563A", - "-150564T", - "-150565G", - "-150566A", - "-150567T", - "A179155-", - "T179156-", - "T179157-", - "A179158-", - "T179159-", - "A179160-", - "T179161-", - "A179162-", - "C179163-", - "A179164-", - "T179165-", - "T179166-", - "A179167-", - "T179168-", - "A179169-", - "T179170-", - "A179171-", - "C179172-", - "A179173-", - "T179174-", - "T179175-", - "A179176-", - "T179177-", - "A179178-", - "T179179-", - "A179180-", - "C179181-", - "A179182-", - "T179183-", - "T179184-", - "A179185-", - "T179186-", - "A179187-", - "T179188-", - "A179189-", - "C179190-", - "A179191-", - "T179192-", - "T179193-", - "A179194-", - "T179195-", - "A179196-", - "T179197-", - "A179198-", - "C179199-", - "A179200-", - "T179201-", - "T179202-", - "A179203-", - "T179204-", - "A179205-", - "T179206-", - "A179207-", - "C179208-" - ], - "OPG124": [ - "L16F" - ] - }, - "labels": { - "aa": "OPG124: L16F", - "clade": "C.1" - } - }, - "children": [ - { - "name": "MPXV/human/Japan/Tokyo/2022/TKY220176", - "node_attrs": { - "div": 560, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "date": { - "value": "2022-10-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2022/TKY220176" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "LC753969" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Japan" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/human/Taiwan/110-093831/2023", - "node_attrs": { - "div": 562, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "date": { - "value": "2023-02-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - }, - "strain_original": { - "value": "MPXV/human/Taiwan/110-093831/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ581853" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Taiwan" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T132513C", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "C185069T" - ] - } - } - }, - { - "name": "MPXV/UZ_REGA_122", - "node_attrs": { - "div": 561, - "author": { - "author": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P.", - "value": "Wawina-Bokalanga,T., Vanmechelen,B., Logist,A.-S., Ysebaert,L., Verlinden,J., Horemans,M., Van Holm,B., Bloemen,M., Maes,P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "KU Leuven, Microbiology, Immunology and Transplantation" - }, - "date": { - "value": "2022-10-28" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - }, - "strain_original": { - "value": "MPXV/UZ_REGA_122" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR035728" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Belgium" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "T133099-", - "G149818A", - "G150551-", - "A150552-", - "T150553-", - "A150554-", - "T150555-", - "G150556-", - "A150557-", - "T150558-", - "G150559-", - "G150560-", - "A150561-", - "T150562-", - "A150563-", - "T150564-", - "G150565-", - "A150566-", - "T150567-", - "-179155A", - "-179156T", - "-179157T", - "-179158A", - "-179159T", - "-179160A", - "-179161T", - "-179162A", - "-179163C", - "-179164A", - "-179165T", - "-179166T", - "-179167A", - "-179168T", - "-179169A", - "-179170T", - "-179171A", - "-179172C", - "-179173A", - "-179174T", - "-179175T", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "T195509-", - "A195510-", - "A195511-" - ], - "OPG176": [ - "D4N" - ] - }, - "labels": { - "aa": "OPG176: D4N" - } - } - }, - { - "name": "MPXV/human/Japan/Tokyo/2022/TKY220165", - "node_attrs": { - "div": 560, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "date": { - "value": "2022-09-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2022/TKY220165" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "LC753968" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Japan" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/human/Japan/Tokyo/2022/TKY220187", - "node_attrs": { - "div": 560, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "date": { - "value": "2022-10-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2022/TKY220187" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "LC753970" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Japan" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "NODE_0000281", - "node_attrs": { - "div": 561, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C3987T" - ] - } - }, - "children": [ - { - "name": "MPXV/human/Taiwan/110-539498/2023", - "node_attrs": { - "div": 566, - "author": { - "author": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y.", - "value": "Lin,J.-H., Chiu,S.-C., Huang,H.-I., Huang,W.-L., Li,T.-Y., Fann,W.-B., Hsieh,P.-Y., Yang,J.-Y." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development" - }, - "date": { - "value": "2023-03-XX" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - }, - "strain_original": { - "value": "MPXV/human/Taiwan/110-539498/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OQ721954" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Taiwan" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "-595T", - "C798T", - "C11923T", - "T14737C", - "C48442T", - "G90825A", - "G102694A", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "A179133-", - "T179134-", - "A179135-", - "C179136-", - "A179137-", - "T179138-", - "T179139-", - "A179140-", - "T179141-", - "A179142-", - "T179143-", - "A179144-", - "C179145-", - "A179146-", - "T179147-", - "T179148-", - "A179149-", - "T179150-", - "A179151-", - "T179152-", - "A179153-", - "C179154-", - "-179176A", - "-179177T", - "-179178A", - "-179179T", - "-179180A", - "-179181C", - "-179182A", - "-179183T", - "-179184T", - "-179185A", - "-179186T", - "-179187A", - "-179188T", - "-179189A", - "-179190C", - "-179191A", - "-179192T", - "-179193T", - "-179194A", - "-179195T", - "-179196A", - "-179197T", - "-179198A", - "-179199C", - "-179200A", - "-179201T", - "-179202T", - "-179203A", - "-179204T", - "-179205A", - "-179206T", - "-179207A", - "-179208C", - "-179209A", - "-179210T", - "-179211T", - "-179212A", - "-179213T", - "-179214A", - "-179215T", - "-179216A", - "-179217C", - "-179218A", - "-179219T", - "-179220T", - "-179221A", - "-179222T", - "-179223A", - "-179224T", - "-179225A", - "-179226C", - "A191312G", - "G196412A" - ], - "NBT03_gp175": [ - "I87V" - ], - "OPG068": [ - "A81V" - ] - }, - "labels": { - "aa": "NBT03_gp175: I87V; OPG068: A81V" - } - } - }, - { - "name": "NODE_0000282", - "node_attrs": { - "div": 562, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C166940T", - "G193223A" - ] - } - }, - "children": [ - { - "name": "MPXV/human/Japan/Tokyo/2023/TKY220318", - "node_attrs": { - "div": 562, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "date": { - "value": "2023-01-25" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2023/TKY220318" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "LC756923" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Japan" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/human/Japan/Tokyo/2023/TKY220342", - "node_attrs": { - "div": 563, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "date": { - "value": "2023-02-09" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2023/TKY220342" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "LC756925" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Japan" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C84734T" - ] - } - } - }, - { - "name": "MPXV/human/Japan/Tokyo/2023/TKY220304", - "node_attrs": { - "div": 564, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K., Harada,S., Amano,A.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K., Harada,S., Amano,A." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "date": { - "value": "2023-01-23" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2023/TKY220304" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "LC760460" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Japan" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "G48887A", - "G75699A" - ], - "OPG096": [ - "R38Q" - ] - }, - "labels": { - "aa": "OPG096: R38Q" - } - } - }, - { - "name": "MPXV/human/Japan/Tokyo/2023/TKY220343", - "node_attrs": { - "div": 563, - "author": { - "author": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K., Harada,S., Amano,A.", - "value": "Kasuya,F., Negishi,A., Kumagai,R., Hasegawa,M., Fujiwara,T., Miyake,H., Nagashima,M., Sadamasu,K., Harada,S., Amano,A." - }, - "region": { - "value": "Asia" - }, - "institution": { - "value": "Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073" - }, - "date": { - "value": "2023-02-13" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - }, - "strain_original": { - "value": "MPXV/human/Japan/Tokyo/2023/TKY220343" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "LC760461" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Japan" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C798T", - "C68765T", - "G196412A" - ], - "OPG086": [ - "M33I" - ] - }, - "labels": { - "aa": "OPG086: M33I" - } - } - }, - { - "name": "NODE_0000283", - "node_attrs": { - "div": 569, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - }, - "outbreak": { - "value": "hMPXV-1" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C21062T", - "G101241A", - "C149963T", - "G152866A", - "A179061-", - "C179062-", - "A179063-", - "T179064-", - "T179065-", - "A179066-", - "T179067-", - "T179068-", - "T179069-", - "A179070-", - "T179071-", - "T179072-", - "T179073-", - "A179074-", - "T179075-", - "G179076-", - "A179077-", - "T179078-", - "A179079-", - "T179080-", - "A179081-", - "C179082-", - "A179083-", - "T179084-", - "T179085-", - "A179086-", - "T179087-", - "A179088-", - "T179089-", - "A179090-", - "C179091-", - "A179092-", - "T179093-", - "T179094-", - "A179095-", - "T179096-", - "A179097-", - "T179098-", - "A179099-", - "C179100-", - "A179101-", - "T179102-", - "T179103-", - "A179104-", - "T179105-", - "A179106-", - "T179107-", - "A179108-", - "C179109-", - "A179110-", - "T179111-", - "T179112-", - "A179113-", - "T179114-", - "A179115-", - "T179116-", - "A179117-", - "C179118-", - "A179119-", - "T179120-", - "T179121-", - "A179122-", - "T179123-", - "A179124-", - "T179125-", - "A179126-", - "C179127-", - "A179128-", - "T179129-", - "T179130-", - "A179131-", - "T179132-", - "G184562A", - "G188348A", - "C188946T", - "A191008-", - "T191009-", - "A191010-", - "A191011-", - "A191012-", - "A191013-", - "A191014-", - "A191015-", - "T191016-", - "G191017-", - "A191018-", - "A191019-", - "A191020-", - "A191021-", - "T191022-", - "C191023-", - "A191024-", - "A191025-", - "T191026-", - "G191027-", - "G191028-", - "C191029-", - "G191030-", - "A191031-", - "A191032-", - "T191033-", - "A191034-", - "A191035-", - "G191036-", - "A191037-", - "C191038-", - "A191039-", - "G191040-", - "T191041-", - "G191042-", - "C191043-", - "G191044-", - "A191045-", - "T191046-", - "T191047-", - "C191048-", - "G191049-", - "C191050-", - "A191051-", - "C191052-", - "C191053-", - "A191054-", - "T191055-", - "G191056-", - "G191057-", - "A191058-", - "G191059-", - "T191060-", - "C191061-", - "G191062-", - "G191063-", - "T191064-", - "A191065-", - "G191066-", - "A191067-", - "T191068-", - "T191069-", - "T191070-", - "C191071-", - "A191072-", - "T191073-", - "G191074-", - "G191075-", - "C191076-", - "T191077-", - "G191078-", - "T191079-", - "C191080-", - "G191081-", - "A191082-", - "T191083-", - "G191084-", - "A196599-", - "C196600-", - "-196602A" - ], - "NBT03_gp175": [ - "M1-", - "E2-", - "S3-", - "V4-", - "D5-", - "F6-", - "M7-", - "A8-", - "V9-", - "D10-", - "E11X", - "*438X" - ], - "OPG036": [ - "M1I" - ], - "OPG176": [ - "S52L" - ], - "OPG180": [ - "D59N" - ] - }, - "labels": { - "aa": "NBT03_gp175: M1-, E2-, S3-, V4-, D5-, F6-, M7-, A8-, V9-, D10-, E11X, *438X; OPG036: M1I; OPG176: S52L; OPG180: D59N" - } - }, - "children": [ - { - "name": "MPXV/PT0630/2023", - "node_attrs": { - "div": 569, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2023-06-22" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - }, - "strain_original": { - "value": "MPXV/PT0630/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR326994" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": {} - } - }, - { - "name": "MPXV/PT0633/2023", - "node_attrs": { - "div": 571, - "author": { - "author": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P.", - "value": "Isidro,J., Borges,V., Pinto,M., Sobral,D., Santos,J., Nunes,A., Mixao,V., Ferreira,R., Santos,D., Duarte,S., Vieira,L., Borrego,M.J., Nuncio,S., Lopes de Carvalho,I., Pelerito,A., Cordeiro,R., Gomes,J.P." - }, - "region": { - "value": "Europe" - }, - "institution": { - "value": "National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases" - }, - "date": { - "value": "2023-06-25" - }, - "clade_membership": { - "value": "IIb" - }, - "lineage": { - "value": "C.1" - }, - "strain_original": { - "value": "MPXV/PT0633/2023" - }, - "outbreak": { - "value": "hMPXV-1" - }, - "strain": { - "value": "OR326997" - }, - "host": { - "value": "Homo sapiens" - }, - "country": { - "value": "Portugal" - } - }, - "branch_attrs": { - "mutations": { - "nuc": [ - "C37738T", - "G151847A", - "G179053-", - "A179054-", - "A179055-", - "G179056-", - "T179057-", - "T179058-", - "T179059-", - "A179060-" - ], - "OPG056": [ - "E433K" - ] - }, - "labels": { - "aa": "OPG056: E433K" - } - } - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } - ] - } -} diff --git a/data_output/index.json b/data_output/index.json index f1f188fa..0ad4a6fe 100644 --- a/data_output/index.json +++ b/data_output/index.json @@ -904,36 +904,12 @@ } }, { - "path": "nextstrain/mpx/hmpxv-b1/pseudo_ON563414", + "path": "nextstrain/mpox/all-clades", "enabled": true, "attributes": { - "name": "Human Monkeypox Lineage B.1*", - "reference name": "MPXV_USA_2022_MA001 in NC_063383 coordinates", - "reference accession": "pseudo_ON563414" - }, - "maintenance": { - "website": [ - "https://nextstrain.org", - "https://clades.nextstrain.org" - ], - "documentation": [ - "https://github.com/nextstrain/nextclade_data", - "https://docs.nextstrain.org/projects/nextclade" - ], - "source code": [ - "https://github.com/nextstrain/nextclade_data", - "https://github.com/neherlab/nextclade_data_workflows" - ], - "issues": [ - "https://github.com/nextstrain/nextclade_data", - "https://github.com/nextstrain/nextclade_data/issues" - ], - "organizations": [ - "Nextstrain" - ], - "authors": [ - "Nextstrain team " - ] + "name": "Mpox virus (All clades)", + "reference accession": "NC_063383.1", + "reference name": "MPXV-M5312_HM12_Rivers" }, "files": { "changelog": "CHANGELOG.md", @@ -950,11 +926,7 @@ "missingData", "mixedSites", "privateMutations", - "snpClusters", "stopCodons" - ], - "other": [ - "mutLabels" ] }, "versions": [ @@ -975,36 +947,12 @@ } }, { - "path": "nextstrain/mpx/hmpxv/NC_063383.1", + "path": "nextstrain/mpox/clade-iib", "enabled": true, "attributes": { - "name": "Human Monkeypox (hMPXV)", - "reference name": "MPXV-M5312_HM12_Rivers", - "reference accession": "NC_063383.1" - }, - "maintenance": { - "website": [ - "https://nextstrain.org", - "https://clades.nextstrain.org" - ], - "documentation": [ - "https://github.com/nextstrain/nextclade_data", - "https://docs.nextstrain.org/projects/nextclade" - ], - "source code": [ - "https://github.com/nextstrain/nextclade_data", - "https://github.com/neherlab/nextclade_data_workflows" - ], - "issues": [ - "https://github.com/nextstrain/nextclade_data", - "https://github.com/nextstrain/nextclade_data/issues" - ], - "organizations": [ - "Nextstrain" - ], - "authors": [ - "Nextstrain team " - ] + "name": "Mpox virus (Clade IIb)", + "reference accession": "NC_063383.1", + "reference name": "MPXV-M5312_HM12_Rivers" }, "files": { "changelog": "CHANGELOG.md", @@ -1043,36 +991,12 @@ } }, { - "path": "nextstrain/mpx/mpxv/ancestral", + "path": "nextstrain/mpox/lineage-b.1", "enabled": true, "attributes": { - "name": "Monkeypox (All Clades)", - "reference name": "Reconstructed ancestral MPXV", - "reference accession": "ancestral" - }, - "maintenance": { - "website": [ - "https://nextstrain.org", - "https://clades.nextstrain.org" - ], - "documentation": [ - "https://github.com/nextstrain/nextclade_data", - "https://docs.nextstrain.org/projects/nextclade" - ], - "source code": [ - "https://github.com/nextstrain/nextclade_data", - "https://github.com/neherlab/nextclade_data_workflows" - ], - "issues": [ - "https://github.com/nextstrain/nextclade_data", - "https://github.com/nextstrain/nextclade_data/issues" - ], - "organizations": [ - "Nextstrain" - ], - "authors": [ - "Nextstrain team " - ] + "name": "Mpox virus (Lineage B.1)", + "reference accession": "NC_063383.1 (with B.1 SNPs)", + "reference name": "MPXV-M5312_HM12_Rivers with B.1 SNPs" }, "files": { "changelog": "CHANGELOG.md", @@ -1089,7 +1013,11 @@ "missingData", "mixedSites", "privateMutations", + "snpClusters", "stopCodons" + ], + "other": [ + "mutLabels" ] }, "versions": [ diff --git a/data_output/minimizer_index.json b/data_output/minimizer_index.json index cf20f9f9..10a8c3b3 100644 --- a/data_output/minimizer_index.json +++ b/data_output/minimizer_index.json @@ -76,7 +76,7 @@ "8576547": "100000000000000000000", "8786415": "100000000000000000000", "8793111": "100000000000000000000", - "9213581": "100000000000000100000", + "9213581": "100000000000000000000", "9259592": "100000000000000000000", "9275108": "100000000000000000000", "9469676": "100000000000000000000", @@ -208,7 +208,7 @@ "26406816": "100000000000000000000", "26408106": "100000000000000000000", "26443542": "100000000000000000000", - "26526994": "100000000000000100000", + "26526994": "100000000000000000000", "26546092": "100000000000000000000", "26686251": "100000000000000000000", "27018248": "100000000000000000000", @@ -698,7 +698,7 @@ "90181018": "100000000000000000000", "90238713": "100000000000000000000", "90348354": "100000000000000000000", - "90394269": "100000000000011000000", + "90394269": "100000000000011100000", "90664366": "100000000000000000000", "90673975": "100000000000000000000", "90750891": "100000000000000000000", @@ -844,7 +844,7 @@ "107630692": "100000000000000000000", "107814645": "100000000000000000000", "108180369": "100000000000000000000", - "108289361": "100000000000000100000", + "108289361": "100000000000000000000", "108308347": "100000000000000000000", "108457697": "100000000000000000000", "108605447": "100000000000000000000", @@ -1357,7 +1357,7 @@ "173139274": "100000000000000000000", "173196032": "100000000000000000000", "173803002": "100000000000000000000", - "174032087": "100000000000011000001", + "174032087": "100000000000011100001", "174094133": "100000000000000000000", "174315030": "100000000000000000000", "174388364": "100000000000000000000", @@ -1455,7 +1455,7 @@ "183878446": "100000000000000000000", "184378076": "100000000000000000000", "184598077": "100000000000000000000", - "184640196": "100000000000011000000", + "184640196": "100000000000011100000", "184802512": "100000000000000000000", "184865968": "100000000000000000000", "185112980": "100000000000000000000", @@ -3023,7 +3023,7 @@ "212500773": "010000000000000000000", "212531410": "010000000000000000000", "212560441": "010000000000000000000", - "212631640": "010000000000011000000", + "212631640": "010000000000011100000", "212922412": "010000000000000000000", "212944563": "010000000000000000000", "212968122": "010000000000000000000", @@ -3618,7 +3618,7 @@ "206404562": "001000000000000000000", "207736106": "001000000000000000000", "208031207": "001000000000000000000", - "208087031": "001000000000000100000", + "208087031": "001000000000000000000", "208966235": "001000000000000000000", "209070589": "001000000000000000000", "209220296": "001000000000000000000", @@ -4465,7 +4465,7 @@ "11825085": "000000000000100000000", "12873731": "000000000000100000000", "13137566": "000000000000100000000", - "13453596": "000000000000100100000", + "13453596": "000000000000100000000", "13604448": "000000000000100000000", "15386393": "000000000000100000000", "16422734": "000000000000100000000", @@ -5108,10 +5108,10 @@ "2713176": "000000000000011100000", "2741096": "000000000000011100000", "2799988": "000000000000011100000", - "2809734": "000000000000011000000", + "2809734": "000000000000011100000", "2811215": "000000000000011100000", "2815441": "000000000000011100000", - "2863003": "000000000000011000000", + "2863003": "000000000000011100000", "2903735": "000000000000011100000", "2923240": "000000000000011100000", "2971562": "000000000000011100000", @@ -5135,7 +5135,7 @@ "3261646": "000000000000011100000", "3271856": "000000000000011100000", "3313621": "000000000000011100000", - "3319842": "000000000000011000000", + "3319842": "000000000000011100000", "3379501": "000000000000011100000", "3386189": "000000000000011100000", "3411200": "000000000000011100000", @@ -5232,7 +5232,7 @@ "5381748": "000000000000011100000", "5382938": "000000000000011100000", "5389708": "000000000000011100000", - "5417949": "000000000000011000000", + "5417949": "000000000000011100000", "5420253": "000000000000011100000", "5452552": "000000000000011100000", "5489541": "000000000000011100000", @@ -5241,15 +5241,15 @@ "5509580": "000000000000011100000", "5537933": "000000000000011100000", "5559017": "000000000000011100000", - "5577319": "000000000000011000000", + "5577319": "000000000000011100000", "5593856": "000000000000011100000", "5601837": "000000000000011100000", "5606083": "000000000000011100000", "5606366": "000000000000011100000", "5748844": "000000000000011100000", - "5758901": "000000000000011000000", + "5758901": "000000000000011100000", "5833648": "000000000000011100000", - "5868254": "000000000000011000000", + "5868254": "000000000000011100000", "5876282": "000000000000011100000", "5908373": "000000000000011100000", "5917503": "000000000000011100000", @@ -5311,6 +5311,7 @@ "7158728": "000000000000011100000", "7180106": "000000000000011100000", "7200072": "000000000000011100000", + "7221347": "000000000000011000000", "7249844": "000000000000011100000", "7254370": "000000000000011100000", "7287259": "000000000000011100000", @@ -5330,7 +5331,7 @@ "7546827": "000000000000011100000", "7608309": "000000000000011100000", "7638455": "000000000000011100000", - "7653366": "000000000000011000000", + "7653366": "000000000000011100000", "7663847": "000000000000011100000", "7689643": "000000000000011100000", "7700605": "000000000000011100000", @@ -5342,7 +5343,7 @@ "7917745": "000000000000011100000", "7965674": "000000000000011100000", "7969977": "000000000000011100000", - "7977827": "000000000000011000000", + "7977827": "000000000000011100000", "8072676": "000000000000011100000", "8078041": "000000000000011100000", "8128720": "000000000000011100000", @@ -5396,7 +5397,7 @@ "9271102": "000000000000011100000", "9292732": "000000000000011100000", "9330024": "000000000000011100000", - "9350312": "000000000000011000000", + "9350312": "000000000000011100000", "9378050": "000000000000011100000", "9379690": "000000000000011100000", "9410220": "000000000000011100110", @@ -5426,11 +5427,10 @@ "9807404": "000000000000011100000", "9842075": "000000000000011100000", "9843997": "000000000000011100000", - "9847062": "000000000000010000110", "9853188": "000000000000011100000", "9918264": "000000000000011100000", "9970430": "000000000000011100000", - "10018543": "000000000000011000000", + "10018543": "000000000000011100000", "10047377": "000000000000011100000", "10085145": "000000000000011100000", "10086269": "000000000000011100000", @@ -5473,7 +5473,7 @@ "10999182": "000000000000011100000", "11002292": "000000000000011100000", "11056676": "000000000000011100000", - "11086092": "000000000000011000000", + "11086092": "000000000000011100000", "11100882": "000000000000011100000", "11138902": "000000000000011100000", "11176271": "000000000000011100000", @@ -5486,7 +5486,7 @@ "11313317": "000000000000011100000", "11316260": "000000000000011100000", "11320670": "000000000000011100000", - "11340664": "000000000000011000000", + "11340664": "000000000000011100000", "11344851": "000000000000011100000", "11364432": "000000000000011100000", "11369910": "000000000000011100000", @@ -5548,7 +5548,7 @@ "12553185": "000000000000011100000", "12563089": "000000000000011100000", "12630115": "000000000000011100000", - "12640382": "000000000000011000000", + "12640382": "000000000000011100000", "12663818": "000000000000011100000", "12692297": "000000000000011100000", "12725775": "000000000000011100000", @@ -5566,7 +5566,7 @@ "12911475": "000000000000011100000", "12921865": "000000000000011100000", "12945198": "000000000000011100000", - "12991696": "000000000000011000000", + "12991696": "000000000000011100000", "13022764": "000000000000011100000", "13076140": "000000000000011100000", "13088257": "000000000000011100000", @@ -5591,7 +5591,7 @@ "13440113": "000000000000011100000", "13462976": "000000000000011100000", "13470287": "000000000000011100000", - "13497507": "000000000000011000000", + "13497507": "000000000000011100000", "13511789": "000000000000011100000", "13546668": "000000000000011100000", "13547677": "000000000000011100000", @@ -5609,7 +5609,7 @@ "13775650": "000000000000011100000", "13776130": "000000000000011100000", "13777537": "000000000000011100000", - "13801192": "000000000000011000000", + "13801192": "000000000000011100000", "13822914": "000000000000011100000", "13860426": "000000000000011100000", "13939543": "000000000000011100000", @@ -5636,7 +5636,7 @@ "14485201": "000000000000011100000", "14494457": "000000000000011100000", "14494970": "000000000000011100000", - "14510479": "000000000000011000000", + "14510479": "000000000000011100000", "14513652": "000000000000011100000", "14515786": "000000000000011100000", "14542335": "000000000000011100000", @@ -5662,7 +5662,7 @@ "15093232": "000000000000011100000", "15098719": "000000000000011100000", "15108615": "000000000000011100000", - "15109633": "000000000000011000000", + "15109633": "000000000000011100000", "15131176": "000000000000011100000", "15147655": "000000000000011100000", "15170775": "000000000000011100000", @@ -5786,7 +5786,7 @@ "17813705": "000000000000011100000", "17851982": "000000000000011100000", "17870259": "000000000000011100000", - "17881321": "000000000000011000000", + "17881321": "000000000000011100000", "17911916": "000000000000011100000", "17917206": "000000000000011100000", "17919273": "000000000000011100000", @@ -5814,7 +5814,7 @@ "18338440": "000000000000011100000", "18365032": "000000000000011100000", "18391500": "000000000000011100000", - "18431190": "000000000000010000000", + "18440025": "000000000000011000000", "18486796": "000000000000011100000", "18541531": "000000000000011100000", "18555677": "000000000000011100000", @@ -5822,7 +5822,7 @@ "18565221": "000000000000011100000", "18580205": "000000000000011100000", "18582784": "000000000000011100000", - "18632347": "000000000000011000000", + "18632347": "000000000000011100000", "18742126": "000000000000011100000", "18771921": "000000000000011100000", "18785656": "000000000000011100000", @@ -5852,12 +5852,12 @@ "19370936": "000000000000011100000", "19375988": "000000000000011100000", "19441896": "000000000000011100000", - "19480438": "000000000000011000000", + "19480438": "000000000000011100000", "19503642": "000000000000011100000", "19657268": "000000000000011100000", "19674590": "000000000000011100000", "19721304": "000000000000011100000", - "19739226": "000000000000011000000", + "19739226": "000000000000011100000", "19754437": "000000000000011100000", "19785245": "000000000000011100000", "19800838": "000000000000011100000", @@ -5897,14 +5897,14 @@ "20575146": "000000000000011100000", "20592955": "000000000000011100000", "20595338": "000000000000011100000", - "20610276": "000000000000011000000", + "20610276": "000000000000011100000", "20633121": "000000000000011100000", "20653526": "000000000000011100000", "20662687": "000000000000011100000", "20676836": "000000000000011100000", "20701177": "000000000000011100000", "20704665": "000000000000011100000", - "20735491": "000000000000011000000", + "20735491": "000000000000011100000", "20805808": "000000000000011100000", "20816577": "000000000000011100000", "20849767": "000000000000011100000", @@ -5984,7 +5984,7 @@ "22454049": "000000000000011100000", "22469070": "000000000000011100000", "22541627": "000000000000011100000", - "22580592": "000000000000011000000", + "22580592": "000000000000011100000", "22590128": "000000000000011100000", "22607788": "000000000000011100000", "22619437": "000000000000011100000", @@ -6062,7 +6062,7 @@ "24323073": "000000000000011111000", "24329110": "000000000000011100000", "24355507": "000000000000011100000", - "24415520": "000000000000011000000", + "24415520": "000000000000011100000", "24442611": "000000000000011100000", "24449078": "000000000000011100000", "24454123": "000000000000011100000", @@ -6183,7 +6183,7 @@ "26948630": "000000000000011110000", "26963507": "000000000000011100000", "26964677": "000000000000011100000", - "26979984": "000000000000011000000", + "26979984": "000000000000011100000", "26980676": "000000000000011100000", "26993703": "000000000000011100000", "26994479": "000000000000011100000", @@ -6198,13 +6198,13 @@ "27169921": "000000000000011100000", "27224722": "000000000000011100000", "27242225": "000000000000011100000", - "27252728": "000000000000011000000", + "27252728": "000000000000011100000", "27270318": "000000000000011100000", "27271528": "000000000000011100000", "27356336": "000000000000011100000", "27360158": "000000000000011100000", "27384333": "000000000000011100000", - "27418428": "000000000000011000000", + "27418428": "000000000000011100000", "27431412": "000000000000011100000", "27450047": "000000000000011100000", "27522015": "000000000000011100000", @@ -6231,7 +6231,7 @@ "27898883": "000000000000011100000", "27981987": "000000000000011100000", "28029195": "000000000000011100000", - "28046415": "000000000000011000000", + "28046415": "000000000000011100000", "28049705": "000000000000011100000", "28061254": "000000000000011100000", "28075228": "000000000000011100000", @@ -6262,7 +6262,6 @@ "28723053": "000000000000011100000", "28753298": "000000000000011100000", "28754133": "000000000000011100000", - "28776162": "000000000000010000000", "28793141": "000000000000011100000", "28821013": "000000000000011100000", "28848654": "000000000000011100000", @@ -6297,7 +6296,7 @@ "29502679": "000000000000011100000", "29519348": "000000000000011100000", "29526780": "000000000000011100000", - "29538114": "000000000000011000000", + "29538114": "000000000000011100000", "29544724": "000000000000011100000", "29610244": "000000000000011100000", "29651744": "000000000000011100000", @@ -6314,9 +6313,9 @@ "29894348": "000000000000011100000", "29895682": "000000000000011100000", "29915126": "000000000000011100000", - "29939162": "000000000000011000000", + "29939162": "000000000000011100000", "29985101": "000000000000011100000", - "30028181": "000000000000011000000", + "30028181": "000000000000011100000", "30079831": "000000000000011100000", "30099080": "000000000000011100000", "30106862": "000000000000011100000", @@ -6343,7 +6342,6 @@ "30788162": "000000000000011100000", "30789929": "000000000000011100000", "30809182": "000000000000011100000", - "30830812": "000000000000010000000", "30866448": "000000000000011100000", "30903329": "000000000000011100000", "30961962": "000000000000011100000", @@ -6434,8 +6432,7 @@ "32755262": "000000000000011100000", "32774009": "000000000000011100000", "32828396": "000000000000011100000", - "32840174": "000000000000011000000", - "32867930": "000000000000010000000", + "32840174": "000000000000011100000", "32881336": "000000000000011100000", "32888316": "000000000000011100000", "32892123": "000000000000011100000", @@ -6450,7 +6447,7 @@ "33098529": "000000000000011100000", "33098604": "000000000000011100000", "33109271": "000000000000011100000", - "33138168": "000000000000011000000", + "33138168": "000000000000011100000", "33138753": "000000000000011100000", "33159811": "000000000000011100000", "33172308": "000000000000011100000", @@ -6497,9 +6494,10 @@ "34115867": "000000000000011100000", "34184601": "000000000000011100000", "34184935": "000000000000011100000", + "34234277": "000000000000011000000", "34247905": "000000000000011100000", "34249642": "000000000000011100000", - "34266447": "000000000000011000000", + "34266447": "000000000000011100000", "34292914": "000000000000011100000", "34312923": "000000000000011100000", "34348941": "000000000000011100000", @@ -6512,7 +6510,7 @@ "34568400": "000000000000011100000", "34584069": "000000000000011100000", "34586394": "000000000000011100000", - "34598351": "000000000000011000000", + "34598351": "000000000000011100000", "34603836": "000000000000011100000", "34619552": "000000000000011100000", "34631847": "000000000000011100000", @@ -6534,7 +6532,7 @@ "35192248": "000000000000011100000", "35250147": "000000000000011100000", "35279671": "000000000000011100000", - "35295599": "000000000000011000000", + "35295599": "000000000000011100000", "35330730": "000000000000011100000", "35347717": "000000000000011100000", "35349204": "000000000000011100000", @@ -6559,7 +6557,7 @@ "35742286": "000000000000011100000", "35760653": "000000000000011100000", "35777696": "000000000000011100000", - "35803847": "000000000000011000000", + "35803847": "000000000000011100000", "35811927": "000000000000011100000", "35817253": "000000000000011100000", "35829276": "000000000000011100000", @@ -6637,14 +6635,14 @@ "37738624": "000000000000011100000", "37912936": "000000000000011100000", "37914490": "000000000000011100000", - "37915179": "000000000000011000000", + "37915179": "000000000000011100000", "37961615": "000000000000011100000", "37973793": "000000000000011100000", "37995845": "000000000000011100000", "38014514": "000000000000011100000", "38017821": "000000000000011100000", "38043060": "000000000000011100000", - "38043144": "000000000000011000000", + "38043144": "000000000000011100000", "38065424": "000000000000011100000", "38123776": "000000000000011100000", "38125206": "000000000000011100000", @@ -6659,13 +6657,11 @@ "38271608": "000000000000011100000", "38308311": "000000000000011100000", "38327629": "000000000000011100000", - "38332370": "000000000000011000000", + "38332370": "000000000000011100000", "38346310": "000000000000011100000", "38370910": "000000000000011100000", "38380571": "000000000000011100000", "38424448": "000000000000011100000", - "38449435": "000000000000010000000", - "38454037": "000000000000010000000", "38455990": "000000000000011100000", "38509446": "000000000000011100000", "38574903": "000000000000011100000", @@ -6724,7 +6720,7 @@ "39774985": "000000000000011100000", "39775767": "000000000000011100000", "39777974": "000000000000011100000", - "39794944": "000000000000011000000", + "39794944": "000000000000011100000", "39800062": "000000000000011100000", "39914554": "000000000000011100000", "39919104": "000000000000011100000", @@ -6774,7 +6770,7 @@ "40935888": "000000000000011100000", "40937216": "000000000000011100000", "40988782": "000000000000011100000", - "40990833": "000000000000011000000", + "40990833": "000000000000011100000", "40998822": "000000000000011100000", "41014467": "000000000000011100000", "41053412": "000000000000011100000", @@ -6836,7 +6832,7 @@ "42222876": "000000000000011100000", "42230318": "000000000000011100000", "42246566": "000000000000011100000", - "42265584": "000000000000011000000", + "42265584": "000000000000011100000", "42269827": "000000000000011100000", "42302585": "000000000000011100000", "42338000": "000000000000011100000", @@ -6960,12 +6956,12 @@ "45335131": "000000000000011100000", "45372822": "000000000000011100000", "45390294": "000000000000011100000", - "45514779": "000000000000011000000", + "45514779": "000000000000011100000", "45563554": "000000000000011100000", "45596908": "000000000000011100000", "45610940": "000000000000011100000", "45614552": "000000000000011100000", - "45620552": "000000000000011000000", + "45620552": "000000000000011100000", "45630206": "000000000000011100000", "45668357": "000000000000011100000", "45734396": "000000000000011100000", @@ -6975,6 +6971,7 @@ "45791782": "000000000000011100000", "45802171": "000000000000011100000", "45824247": "000000000000011100000", + "45847456": "000000000000011000000", "45856721": "000000000000011100000", "45872918": "000000000000011100000", "45876697": "000000000000011100000", @@ -7057,7 +7054,7 @@ "48007832": "000000000000011100000", "48010292": "000000000000011100000", "48061707": "000000000000011100000", - "48077972": "000000000000011000000", + "48077972": "000000000000011100000", "48079694": "000000000000011100000", "48125053": "000000000000011100000", "48126166": "000000000000011100000", @@ -7107,6 +7104,7 @@ "49159211": "000000000000011100000", "49173883": "000000000000011100000", "49189817": "000000000000011100000", + "49191733": "000000000000011000000", "49265053": "000000000000011100000", "49281123": "000000000000011100000", "49282165": "000000000000011100000", @@ -7138,7 +7136,7 @@ "49994794": "000000000000011100000", "50003071": "000000000000011100000", "50106743": "000000000000011100000", - "50137850": "000000000000011000000", + "50137850": "000000000000011100000", "50148228": "000000000000011100000", "50165109": "000000000000011100000", "50202176": "000000000000011100000", @@ -7182,7 +7180,7 @@ "50994910": "000000000000011100000", "51049906": "000000000000011100000", "51061827": "000000000000011100000", - "51075727": "000000000000011000000", + "51075727": "000000000000011100000", "51085950": "000000000000011100000", "51092602": "000000000000011100000", "51164664": "000000000000011100000", @@ -7210,6 +7208,7 @@ "51646270": "000000000000011100000", "51653710": "000000000000011100000", "51664020": "000000000000011100000", + "51768546": "000000000000011000000", "51827665": "000000000000011100000", "51829115": "000000000000011100000", "51848913": "000000000000011100000", @@ -7229,7 +7228,6 @@ "52451427": "000000000000011100000", "52463798": "000000000000011100000", "52489446": "000000000000011100000", - "52490238": "000000000000010100000", "52509122": "000000000000011100000", "52567664": "000000000000011100000", "52571750": "000000000000011100000", @@ -7260,7 +7258,7 @@ "53174184": "000000000000011100000", "53192277": "000000000000011100000", "53270103": "000000000000011100000", - "53271540": "000000000000011000000", + "53271540": "000000000000011100000", "53283096": "000000000000011100000", "53290515": "000000000000011100000", "53303759": "000000000000011100000", @@ -7300,7 +7298,7 @@ "53833455": "000000000000011100000", "53835117": "000000000000011100000", "53847882": "000000000000011100000", - "53852161": "000000000000011000000", + "53852161": "000000000000011100000", "53871161": "000000000000011100000", "53891058": "000000000000011100000", "53893237": "000000000000011100000", @@ -7341,7 +7339,7 @@ "54624665": "000000000000011100000", "54635945": "000000000000011100000", "54653977": "000000000000011100000", - "54669774": "000000000000011000000", + "54669774": "000000000000011100000", "54678930": "000000000000011100000", "54689976": "000000000000011100000", "54700198": "000000000000011100000", @@ -7357,7 +7355,7 @@ "54971026": "000000000000011100000", "54986871": "000000000000011100000", "55004974": "000000000000011100000", - "55076422": "000000000000011000000", + "55076422": "000000000000011100000", "55083724": "000000000000011100000", "55101314": "000000000000011100000", "55102960": "000000000000011100000", @@ -7381,7 +7379,7 @@ "55530515": "000000000000011100000", "55539450": "000000000000011100000", "55561928": "000000000000011100000", - "55572386": "000000000000011000000", + "55572386": "000000000000011100000", "55595309": "000000000000011100000", "55628024": "000000000000011100000", "55694936": "000000000000011100000", @@ -7390,7 +7388,7 @@ "55735038": "000000000000011100000", "55746067": "000000000000011100000", "55748288": "000000000000011100000", - "55764614": "000000000000011000000", + "55764614": "000000000000011100000", "55778743": "000000000000011100000", "55790898": "000000000000011100000", "55791861": "000000000000011100000", @@ -7461,7 +7459,7 @@ "57092450": "000000000000011100000", "57102662": "000000000000011100000", "57131411": "000000000000011100000", - "57132032": "000000000000011000000", + "57132032": "000000000000011100000", "57138301": "000000000000011100000", "57151077": "000000000000011100000", "57168021": "000000000000011100000", @@ -7478,9 +7476,8 @@ "57344937": "000000000000011100000", "57346169": "000000000000011100000", "57469424": "000000000000011100000", - "57474379": "000000000000011000000", + "57474379": "000000000000011100000", "57508072": "000000000000011100000", - "57537392": "000000000000010000000", "57540190": "000000000000011100000", "57551596": "000000000000011100000", "57561032": "000000000000011100000", @@ -7493,10 +7490,10 @@ "57709009": "000000000000011100000", "57729704": "000000000000011100110", "57742604": "000000000000011100000", - "57760409": "000000000000011000000", + "57760409": "000000000000011100000", "57760446": "000000000000011100000", "57771993": "000000000000011100000", - "57801839": "000000000000011000000", + "57801839": "000000000000011100000", "57807728": "000000000000011100000", "57837978": "000000000000011100000", "57859923": "000000000000011100000", @@ -7508,7 +7505,7 @@ "58038729": "000000000000011100000", "58057270": "000000000000011100000", "58059756": "000000000000011100000", - "58102586": "000000000000011000000", + "58102586": "000000000000011100000", "58139109": "000000000000011100000", "58151716": "000000000000011100000", "58172459": "000000000000011100000", @@ -7523,9 +7520,9 @@ "58492029": "000000000000011100000", "58513802": "000000000000011100000", "58521764": "000000000000011100000", - "58524761": "000000000000011000000", + "58524761": "000000000000011100000", "58568553": "000000000000011100000", - "58641381": "000000000000011000000", + "58641381": "000000000000011100000", "58662703": "000000000000011100000", "58673804": "000000000000011100000", "58674120": "000000000000011100000", @@ -7541,11 +7538,11 @@ "58848137": "000000000000011100000", "58860233": "000000000000011100000", "58860385": "000000000000011100000", - "58863150": "000000000000011000000", + "58863150": "000000000000011100000", "58905715": "000000000000011100000", "58935879": "000000000000011100000", "58938618": "000000000000011100000", - "58965336": "000000000000011000000", + "58965336": "000000000000011100000", "58987824": "000000000000011100000", "59016036": "000000000000011100000", "59029852": "000000000000011100000", @@ -7579,7 +7576,7 @@ "59746239": "000000000000011100000", "59760621": "000000000000011100000", "59813227": "000000000000011100000", - "59877230": "000000000000011000000", + "59877230": "000000000000011100000", "59880963": "000000000000011100000", "59912109": "000000000000011100000", "59968169": "000000000000011100000", @@ -7634,7 +7631,7 @@ "61048276": "000000000000011100000", "61062428": "000000000000011100000", "61065402": "000000000000011100000", - "61082692": "000000000000011000000", + "61082692": "000000000000011100000", "61083460": "000000000000011100000", "61104717": "000000000000011100000", "61118173": "000000000000011100000", @@ -7658,7 +7655,7 @@ "61568059": "000000000000011100000", "61584985": "000000000000011100000", "61590313": "000000000000011100000", - "61707494": "000000000000011000000", + "61707494": "000000000000011100000", "61740141": "000000000000011100000", "61789743": "000000000000011100000", "61790394": "000000000000011100000", @@ -7719,7 +7716,7 @@ "63331878": "000000000000011100000", "63346506": "000000000000011100000", "63348144": "000000000000011100000", - "63370865": "000000000000011000000", + "63370865": "000000000000011100000", "63378865": "000000000000011100000", "63389304": "000000000000011100000", "63412515": "000000000000011100000", @@ -7782,11 +7779,10 @@ "64786104": "000000000000011100000", "64794720": "000000000000011100000", "64867370": "000000000000011100000", - "64931916": "000000000000010000000", "64932564": "000000000000011100000", "65004308": "000000000000011100000", "65035689": "000000000000011100000", - "65044933": "000000000000011000000", + "65044933": "000000000000011100000", "65050205": "000000000000011100000", "65142236": "000000000000011100000", "65194047": "000000000000011100000", @@ -7812,7 +7808,7 @@ "65444588": "000000000000011100000", "65468913": "000000000000011100000", "65473936": "000000000000011100000", - "65526225": "000000000000011000000", + "65526225": "000000000000011100000", "65529939": "000000000000011100000", "65534756": "000000000000011100000", "65589264": "000000000000011100000", @@ -7834,7 +7830,7 @@ "65886693": "000000000000011100000", "65889489": "000000000000011100000", "65895014": "000000000000011100000", - "65905798": "000000000000011000000", + "65905798": "000000000000011100000", "65924462": "000000000000011100000", "65925765": "000000000000011100000", "65929374": "000000000000011100000", @@ -7866,7 +7862,7 @@ "66445220": "000000000000011100000", "66464464": "000000000000011100000", "66475250": "000000000000011100000", - "66477952": "000000000000011000000", + "66477952": "000000000000011100000", "66488068": "000000000000011100000", "66491098": "000000000000011100000", "66500466": "000000000000011100000", @@ -7874,7 +7870,7 @@ "66529721": "000000000000011100000", "66530322": "000000000000011100000", "66542981": "000000000000011100000", - "66574933": "000000000000011000000", + "66574933": "000000000000011100000", "66583580": "000000000000011100000", "66612319": "000000000000011100000", "66618877": "000000000000011100000", @@ -7890,7 +7886,7 @@ "66771751": "000000000000011100110", "66774136": "000000000000011100000", "66777694": "000000000000011100000", - "66788183": "000000000000011000000", + "66788183": "000000000000011100000", "66796402": "000000000000011100000", "66807610": "000000000000011100000", "66839448": "000000000000011100000", @@ -7920,7 +7916,7 @@ "67314378": "000000000000011100000", "67344100": "000000000000011100000", "67349923": "000000000000011100000", - "67434818": "000000000000011000000", + "67434818": "000000000000011100000", "67469589": "000000000000011100000", "67501803": "000000000000011100000", "67532147": "000000000000011100000", @@ -7939,7 +7935,7 @@ "67850269": "000000000000011100000", "67870294": "000000000000011100000", "67872513": "000000000000011100000", - "67904239": "000000000000011000000", + "67904239": "000000000000011100000", "67908402": "000000000000011100000", "67920268": "000000000000011100000", "67931073": "000000000000011100000", @@ -7959,8 +7955,8 @@ "68162760": "000000000000011100000", "68208472": "000000000000011100000", "68252125": "000000000000011100000", - "68263961": "000000000000011000000", - "68278127": "000000000000011000000", + "68263961": "000000000000011100000", + "68278127": "000000000000011100000", "68286037": "000000000000011100000", "68300426": "000000000000011100000", "68306551": "000000000000011100000", @@ -7978,7 +7974,7 @@ "68526023": "000000000000011100000", "68546918": "000000000000011100000", "68552703": "000000000000011100000", - "68599304": "000000000000011000000", + "68599304": "000000000000011100000", "68654697": "000000000000011100000", "68665862": "000000000000011100000", "68673170": "000000000000011100000", @@ -7997,7 +7993,6 @@ "68916826": "000000000000011100000", "68971165": "000000000000011100000", "68982379": "000000000000011100000", - "69027804": "000000000000010000000", "69106971": "000000000000011100000", "69111983": "000000000000011100000", "69130965": "000000000000011100000", @@ -8005,7 +8000,7 @@ "69162951": "000000000000011100000", "69166766": "000000000000011100000", "69181424": "000000000000011100000", - "69229301": "000000000000011000000", + "69229301": "000000000000011100000", "69255380": "000000000000011100000", "69311188": "000000000000011100000", "69312494": "000000000000011100000", @@ -8023,7 +8018,7 @@ "69494413": "000000000000011100000", "69501224": "000000000000011100000", "69537200": "000000000000011100000", - "69549179": "000000000000011000000", + "69549179": "000000000000011100000", "69585052": "000000000000011100000", "69585223": "000000000000011100000", "69646303": "000000000000011100000", @@ -8084,9 +8079,9 @@ "70612490": "000000000000011100000", "70618934": "000000000000011100000", "70623918": "000000000000011100000", - "70646724": "000000000000011000000", + "70646724": "000000000000011100000", "70665742": "000000000000011100000", - "70678560": "000000000000011000000", + "70678560": "000000000000011100000", "70701607": "000000000000011100000", "70703012": "000000000000011100000", "70717414": "000000000000011100000", @@ -8096,13 +8091,13 @@ "70730098": "000000000000011100000", "70755489": "000000000000011100000", "70763579": "000000000000011100000", - "70773332": "000000000000011000000", + "70773332": "000000000000011100000", "70787283": "000000000000011100000", "70794989": "000000000000011100000", "70883656": "000000000000011100000", "70904887": "000000000000011100000", "70918007": "000000000000011100000", - "70928951": "000000000000011000000", + "70928951": "000000000000011100000", "70963442": "000000000000011100000", "71020025": "000000000000011100000", "71045442": "000000000000011100000", @@ -8116,7 +8111,7 @@ "71220756": "000000000000011100000", "71231130": "000000000000011100000", "71235026": "000000000000011100000", - "71330829": "000000000000011000000", + "71330829": "000000000000011100000", "71364766": "000000000000011100000", "71397053": "000000000000011100000", "71422404": "000000000000011100000", @@ -8138,7 +8133,7 @@ "71798307": "000000000000011100000", "71836359": "000000000000011100000", "71848137": "000000000000011100000", - "71851336": "000000000000011000000", + "71851336": "000000000000011100000", "71928386": "000000000000011100000", "71930321": "000000000000011100000", "71952476": "000000000000011100000", @@ -8152,7 +8147,7 @@ "72084392": "000000000000011100000", "72091894": "000000000000011100000", "72106375": "000000000000011100000", - "72128729": "000000000000011000000", + "72128729": "000000000000011100000", "72172728": "000000000000011100000", "72192780": "000000000000011100000", "72279141": "000000000000011100000", @@ -8206,12 +8201,12 @@ "73865870": "000000000000011100000", "73884299": "000000000000011100110", "73971434": "000000000000011100000", - "73975153": "000000000000011000000", + "73975153": "000000000000011100000", "74027938": "000000000000011100000", "74028452": "000000000000011100000", "74045724": "000000000000011100000", "74117025": "000000000000011100000", - "74127673": "000000000000011000000", + "74127673": "000000000000011100000", "74137199": "000000000000011100000", "74181607": "000000000000011100000", "74192853": "000000000000011100000", @@ -8223,7 +8218,6 @@ "74359052": "000000000000011100000", "74448249": "000000000000011100000", "74479322": "000000000000011100000", - "74492946": "000000000000010000000", "74520881": "000000000000011100000", "74527939": "000000000000011100000", "74532027": "000000000000011100000", @@ -8243,20 +8237,20 @@ "75018555": "000000000000011100000", "75025139": "000000000000011100000", "75026857": "000000000000011101000", - "75037633": "000000000000011000000", + "75037633": "000000000000011100000", "75055082": "000000000000011100000", "75080263": "000000000000011100000", "75091339": "000000000000011100000", "75109487": "000000000000011100000", "75112214": "000000000000011100000", "75146083": "000000000000011100000", - "75150374": "000000000000011000000", + "75150374": "000000000000011100000", "75157578": "000000000000011100000", "75253520": "000000000000011100000", "75259407": "000000000000011100000", - "75262045": "000000000000011000000", + "75262045": "000000000000011100000", "75263015": "000000000000011100000", - "75292169": "000000000000011000000", + "75292169": "000000000000011100000", "75308241": "000000000000011100000", "75359589": "000000000000011100000", "75383519": "000000000000011100000", @@ -8271,7 +8265,7 @@ "75592406": "000000000000011100000", "75642276": "000000000000011100000", "75657511": "000000000000011100000", - "75669451": "000000000000011000000", + "75669451": "000000000000011100000", "75702423": "000000000000011100000", "75736275": "000000000000011100000", "75742835": "000000000000011100000", @@ -8291,12 +8285,12 @@ "75976688": "000000000000011100000", "76010233": "000000000000011100000", "76017178": "000000000000011100000", - "76017519": "000000000000011000000", + "76017519": "000000000000011100000", "76052784": "000000000000011100000", "76062919": "000000000000011100000", "76069411": "000000000000011100000", "76073532": "000000000000011100000", - "76085861": "000000000000011000000", + "76085861": "000000000000011100000", "76106134": "000000000000011100000", "76115313": "000000000000011100000", "76116263": "000000000000011100000", @@ -8336,7 +8330,7 @@ "76742108": "000000000000011100000", "76778209": "000000000000011100000", "76789355": "000000000000011100000", - "76798507": "000000000000011000000", + "76798507": "000000000000011100000", "76857253": "000000000000011100000", "76923037": "000000000000011100000", "76940418": "000000000000011100000", @@ -8440,7 +8434,7 @@ "79376044": "000000000000011100000", "79393412": "000000000000011100000", "79405364": "000000000000011100000", - "79416099": "000000000000011000000", + "79416099": "000000000000011100000", "79459365": "000000000000011100000", "79468737": "000000000000011100000", "79487667": "000000000000011100000", @@ -8478,7 +8472,7 @@ "80429284": "000000000000011100000", "80449023": "000000000000011100000", "80456119": "000000000000011100000", - "80469670": "000000000000011000000", + "80469670": "000000000000011100000", "80490786": "000000000000011100000", "80499647": "000000000000011100000", "80517568": "000000000000011100000", @@ -8489,7 +8483,7 @@ "80650978": "000000000000011100000", "80675009": "000000000000011100000", "80675882": "000000000000011100000", - "80698755": "000000000000011000000", + "80698755": "000000000000011100000", "80718406": "000000000000011100000", "80726683": "000000000000011100000", "80819225": "000000000000011100000", @@ -8591,7 +8585,7 @@ "83099731": "000000000000011100000", "83106836": "000000000000011100000", "83193469": "000000000000011100000", - "83228567": "000000000000011000000", + "83228567": "000000000000011100000", "83238957": "000000000000011100000", "83244561": "000000000000011100000", "83248686": "000000000000011100000", @@ -8624,7 +8618,6 @@ "83741825": "000000000000011100000", "83767738": "000000000000011100000", "83775250": "000000000000011100000", - "83838804": "000000000000010000000", "83872631": "000000000000011100000", "83878793": "000000000000011100000", "83888556": "000000000000011100000", @@ -8688,10 +8681,11 @@ "85046649": "000000000000011100000", "85053815": "000000000000011100000", "85063205": "000000000000011100000", + "85080806": "000000000000011000000", "85090971": "000000000000011100000", "85123994": "000000000000011100000", "85188189": "000000000000011100000", - "85207245": "000000000000011000000", + "85207245": "000000000000011100000", "85207492": "000000000000011100000", "85208895": "000000000000011100000", "85215827": "000000000000011100000", @@ -8705,9 +8699,7 @@ "85276091": "000000000000011100000", "85288252": "000000000000011100000", "85300279": "000000000000011100000", - "85332092": "000000000000010000000", "85348455": "000000000000011100000", - "85350628": "000000000000010000000", "85371140": "000000000000011100000", "85376432": "000000000000011100000", "85387347": "000000000000011100000", @@ -8726,10 +8718,10 @@ "85635938": "000000000000011100000", "85648424": "000000000000011100000", "85709960": "000000000000011100000", - "85715418": "000000000000011000000", + "85715418": "000000000000011100000", "85762067": "000000000000011100000", "85791693": "000000000000011100000", - "85822286": "000000000000011000000", + "85822286": "000000000000011100000", "85855323": "000000000000011100000", "85874633": "000000000000011100000", "85896932": "000000000000011100000", @@ -8740,6 +8732,7 @@ "86109835": "000000000000011100000", "86134170": "000000000000011100000", "86142434": "000000000000011100000", + "86153616": "000000000000011000000", "86228989": "000000000000011100000", "86260356": "000000000000011100000", "86311875": "000000000000011100000", @@ -8809,7 +8802,7 @@ "87572124": "000000000000011100000", "87580107": "000000000000011100000", "87659571": "000000000000011100000", - "87731987": "000000000000011000000", + "87731987": "000000000000011100000", "87809668": "000000000000011100000", "87811456": "000000000000011100000", "87822371": "000000000000011100000", @@ -8821,11 +8814,11 @@ "87914603": "000000000000011100000", "87922230": "000000000000011100110", "87991395": "000000000000011100000", - "87996062": "000000000000011000000", + "87996062": "000000000000011100000", "88025261": "000000000000011100000", "88049753": "000000000000011100000", "88106158": "000000000000011100000", - "88122025": "000000000000011000000", + "88122025": "000000000000011100000", "88146499": "000000000000011100000", "88181566": "000000000000011100000", "88204155": "000000000000011100000", @@ -8847,7 +8840,6 @@ "88485687": "000000000000011100000", "88486731": "000000000000011100000", "88498292": "000000000000011100000", - "88501328": "000000000000010000000", "88575343": "000000000000011100000", "88581757": "000000000000011100000", "88596139": "000000000000011100000", @@ -8871,7 +8863,7 @@ "88959034": "000000000000011100000", "89021076": "000000000000011100000", "89041824": "000000000000011100000", - "89082057": "000000000000011000000", + "89082057": "000000000000011100000", "89098041": "000000000000011100000", "89107760": "000000000000011100000", "89159505": "000000000000011100000", @@ -8890,7 +8882,7 @@ "89304749": "000000000000011100000", "89319126": "000000000000011100000", "89383564": "000000000000011100000", - "89440683": "000000000000011000000", + "89440683": "000000000000011100000", "89449227": "000000000000011100000", "89462134": "000000000000011100000", "89489746": "000000000000011100000", @@ -8925,6 +8917,7 @@ "90383403": "000000000000011100000", "90386603": "000000000000011100000", "90454432": "000000000000011100000", + "90460966": "000000000000011000000", "90462691": "000000000000011100000", "90497131": "000000000000011100000", "90497173": "000000000000011100000", @@ -8944,9 +8937,9 @@ "90900316": "000000000000011100000", "90917029": "000000000000011100000", "90939654": "000000000000011100000", - "90985839": "000000000000011000000", + "90985839": "000000000000011100000", "90993736": "000000000000011100000", - "91001631": "000000000000011000000", + "91001631": "000000000000011100000", "91004552": "000000000000011100000", "91055932": "000000000000011100000", "91085077": "000000000000011100000", @@ -9002,7 +8995,6 @@ "92111112": "000000000000011100000", "92118788": "000000000000011100000", "92202451": "000000000000011100000", - "92208081": "000000000000010100000", "92256367": "000000000000011100000", "92258486": "000000000000011100000", "92301984": "000000000000011100000", @@ -9027,7 +9019,6 @@ "92676883": "000000000000011100000", "92686909": "000000000000011100000", "92695857": "000000000000011100000", - "92715394": "000000000000010000000", "92726764": "000000000000011100000", "92731451": "000000000000011100000", "92762513": "000000000000011100000", @@ -9063,7 +9054,7 @@ "93355243": "000000000000011100000", "93477551": "000000000000011100000", "93511571": "000000000000011100000", - "93527813": "000000000000011000000", + "93527813": "000000000000011100000", "93547658": "000000000000011100000", "93559689": "000000000000011100000", "93561788": "000000000000011100000", @@ -9105,11 +9096,11 @@ "94343648": "000000000000011100000", "94395355": "000000000000011100000", "94450650": "000000000000011100000", - "94473449": "000000000000011000000", + "94473449": "000000000000011100000", "94475826": "000000000000011100000", "94483823": "000000000000011100000", "94539625": "000000000000011100000", - "94555857": "000000000000011000000", + "94555857": "000000000000011100000", "94588252": "000000000000011100000", "94602271": "000000000000011100000", "94643261": "000000000000011100000", @@ -9126,13 +9117,13 @@ "94881151": "000000000000011100000", "94883741": "000000000000011100000", "94893546": "000000000000011100000", - "94904696": "000000000000011000000", + "94904696": "000000000000011100000", "95024395": "000000000000011100000", "95037180": "000000000000011100000", "95073078": "000000000000011100000", "95076386": "000000000000011100000", "95089731": "000000000000011100000", - "95089764": "000000000000011000000", + "95089764": "000000000000011100000", "95098014": "000000000000011100000", "95117358": "000000000000011100000", "95118744": "000000000000011100000", @@ -9170,7 +9161,7 @@ "95778008": "000000000000011100000", "95796464": "000000000000011100000", "95901640": "000000000000011100000", - "95920630": "000000000000011000000", + "95920630": "000000000000011100000", "95949406": "000000000000011100000", "95965870": "000000000000011100000", "95986315": "000000000000011100000", @@ -9188,7 +9179,7 @@ "96262994": "000000000000011100000", "96285465": "000000000000011100000", "96327391": "000000000000011100000", - "96419354": "000000000000011000000", + "96419354": "000000000000011100000", "96445959": "000000000000011100000", "96452553": "000000000000011100000", "96504061": "000000000000011100000", @@ -9200,19 +9191,19 @@ "96677917": "000000000000011100000", "96681773": "000000000000011100110", "96690381": "000000000000011100000", - "96739676": "000000000000011000000", + "96739676": "000000000000011100000", "96750406": "000000000000011100000", "96753524": "000000000000011100000", "96774422": "000000000000011100000", "96777134": "000000000000011100000", "96779249": "000000000000011100000", - "96781359": "000000000000011000000", + "96781359": "000000000000011100000", "96784473": "000000000000011100000", "96804761": "000000000000011100000", "96810438": "000000000000011100000", "96819547": "000000000000011100000", "96833103": "000000000000011100000", - "96867870": "000000000000011000000", + "96867870": "000000000000011100000", "96876495": "000000000000011100000", "96900451": "000000000000011100000", "96928212": "000000000000011100000", @@ -9220,6 +9211,7 @@ "96954488": "000000000000011100000", "96963667": "000000000000011100000", "96966192": "000000000000011100000", + "96998652": "000000000000011000000", "97016989": "000000000000011100000", "97026606": "000000000000011100000", "97048445": "000000000000011100000", @@ -9251,7 +9243,6 @@ "97526986": "000000000000011100000", "97538867": "000000000000011100000", "97549321": "000000000000011100000", - "97559091": "000000000000010000000", "97611291": "000000000000011100000", "97612659": "000000000000011100000", "97641264": "000000000000011100000", @@ -9262,7 +9253,7 @@ "97717992": "000000000000011100000", "97735149": "000000000000011100000", "97749158": "000000000000011100000", - "97767235": "000000000000011000000", + "97767235": "000000000000011100000", "97840439": "000000000000011100000", "97845459": "000000000000011100000", "97965687": "000000000000011100000", @@ -9277,7 +9268,7 @@ "98134845": "000000000000011100000", "98183466": "000000000000011100000", "98225116": "000000000000011100000", - "98277925": "000000000000011000000", + "98277925": "000000000000011100000", "98281114": "000000000000011100000", "98281560": "000000000000011100000", "98287067": "000000000000011100000", @@ -9305,7 +9296,7 @@ "98650169": "000000000000011100000", "98686322": "000000000000011100000", "98697895": "000000000000011100000", - "98742328": "000000000000011000000", + "98742328": "000000000000011100000", "98762506": "000000000000011100000", "98767031": "000000000000011100000", "98770944": "000000000000011100000", @@ -9321,7 +9312,7 @@ "98904934": "000000000000011100000", "98913324": "000000000000011100000", "98957743": "000000000000011100000", - "99019312": "000000000000011000000", + "99019312": "000000000000011100000", "99038524": "000000000000011100000", "99081529": "000000000000011100000", "99085221": "000000000000011100000", @@ -9332,7 +9323,7 @@ "99238307": "000000000000011100000", "99303430": "000000000000011100000", "99313495": "000000000000011100000", - "99389234": "000000000000011000000", + "99389234": "000000000000011100000", "99397744": "000000000000011100000", "99427938": "000000000000011100000", "99441469": "000000000000011100000", @@ -9359,7 +9350,6 @@ "99919889": "000000000000011100000", "99937661": "000000000000011100000", "99962835": "000000000000011100000", - "100000447": "000000000000010000000", "100039134": "000000000000011100000", "100059959": "000000000000011100000", "100062253": "000000000000011100000", @@ -9370,7 +9360,7 @@ "100130315": "000000000000011100000", "100148478": "000000000000011100000", "100155034": "000000000000011100000", - "100193904": "000000000000011000000", + "100193904": "000000000000011100000", "100205203": "000000000000011100000", "100231470": "000000000000011100000", "100256678": "000000000000011100000", @@ -9403,7 +9393,6 @@ "101022218": "000000000000011100000", "101051716": "000000000000011100000", "101065596": "000000000000011100000", - "101071879": "000000000000010000000", "101183417": "000000000000011100000", "101201758": "000000000000011100000", "101239872": "000000000000011100000", @@ -9426,7 +9415,7 @@ "101633220": "000000000000011100000", "101645324": "000000000000011100000", "101654277": "000000000000011100000", - "101665829": "000000000000011000000", + "101665829": "000000000000011100000", "101674359": "000000000000011100000", "101680150": "000000000000011100000", "101681906": "000000000000011100000", @@ -9434,12 +9423,13 @@ "101714456": "000000000000011100000", "101716796": "000000000000011100000", "101717394": "000000000000011100000", + "101743985": "000000000000011000000", "101753507": "000000000000011100000", "101764917": "000000000000011100000", "101784159": "000000000000011100000", "101789778": "000000000000011100000", "101811950": "000000000000011100000", - "101829396": "000000000000011000000", + "101829396": "000000000000011100000", "101830177": "000000000000011100000", "101838417": "000000000000011100000", "101842978": "000000000000011100000", @@ -9458,8 +9448,8 @@ "102202839": "000000000000011100000", "102282865": "000000000000011100000", "102299660": "000000000000011100000", - "102304111": "000000000000011000000", - "102313818": "000000000000011000000", + "102304111": "000000000000011100000", + "102313818": "000000000000011100000", "102328773": "000000000000011100000", "102351049": "000000000000011100000", "102377910": "000000000000011100000", @@ -9517,20 +9507,20 @@ "103448512": "000000000000011100000", "103471400": "000000000000011100000", "103476542": "000000000000011100000", - "103517658": "000000000000011000000", + "103517658": "000000000000011100000", "103522390": "000000000000011100000", "103533648": "000000000000011100000", "103537519": "000000000000011100000", "103544244": "000000000000011100000", "103585781": "000000000000011100000", "103704065": "000000000000011100000", - "103730083": "000000000000011000000", + "103730083": "000000000000011100000", "103744134": "000000000000011100000", "103750238": "000000000000011100000", "103760206": "000000000000011100000", "103786330": "000000000000011100000", "103787510": "000000000000011100000", - "103829469": "000000000000011000000", + "103829469": "000000000000011100000", "103857516": "000000000000011100000", "103883026": "000000000000011100000", "103887961": "000000000000011100000", @@ -9538,7 +9528,7 @@ "103916446": "000000000000011100000", "103942744": "000000000000011100000", "103976499": "000000000000011100000", - "103998261": "000000000000011000000", + "103998261": "000000000000011100000", "104000661": "000000000000011100000", "104016693": "000000000000011100000", "104023494": "000000000000011100000", @@ -9576,7 +9566,7 @@ "104619608": "000000000000011100000", "104684684": "000000000000011100000", "104695432": "000000000000011100000", - "104706272": "000000000000011000000", + "104706272": "000000000000011100000", "104717557": "000000000000011100000", "104721059": "000000000000011100000", "104755562": "000000000000011100000", @@ -9590,7 +9580,7 @@ "104953267": "000000000000011100000", "104986073": "000000000000011100000", "105009841": "000000000000011100000", - "105019253": "000000000000011000000", + "105019253": "000000000000011100000", "105042538": "000000000000011100000", "105071950": "000000000000011100000", "105083904": "000000000000011100000", @@ -9600,8 +9590,8 @@ "105171319": "000000000000011100000", "105174886": "000000000000011100000", "105194273": "000000000000011100000", - "105196302": "000000000000011000000", - "105220836": "000000000000011000000", + "105196302": "000000000000011100000", + "105220836": "000000000000011100000", "105221916": "000000000000011100000", "105270141": "000000000000011100000", "105285278": "000000000000011100000", @@ -9650,7 +9640,7 @@ "106297706": "000000000000011100000", "106301519": "000000000000011100000", "106308752": "000000000000011100000", - "106320556": "000000000000011000000", + "106320556": "000000000000011100000", "106378945": "000000000000011100000", "106385488": "000000000000011100000", "106410285": "000000000000011100000", @@ -9669,7 +9659,7 @@ "106725538": "000000000000011100000", "106728709": "000000000000011100000", "106740991": "000000000000011100000", - "106833948": "000000000000011000000", + "106833948": "000000000000011100000", "106903875": "000000000000011100000", "106940888": "000000000000011100000", "106949699": "000000000000011100000", @@ -9688,7 +9678,7 @@ "107226297": "000000000000011100000", "107266768": "000000000000011100000", "107273224": "000000000000011100000", - "107310483": "000000000000011000000", + "107310483": "000000000000011100000", "107320733": "000000000000011100000", "107325393": "000000000000011100000", "107329346": "000000000000011100000", @@ -9715,7 +9705,7 @@ "107758644": "000000000000011100000", "107779288": "000000000000011100000", "107784856": "000000000000011100000", - "107826566": "000000000000011000000", + "107826566": "000000000000011100000", "107855743": "000000000000011100000", "107868480": "000000000000011100000", "107869012": "000000000000011100000", @@ -9777,7 +9767,7 @@ "108790787": "000000000000011100000", "108793335": "000000000000011100000", "108807944": "000000000000011100000", - "108838291": "000000000000011000000", + "108838291": "000000000000011100000", "108855709": "000000000000011100000", "108875881": "000000000000011100000", "108892221": "000000000000011100000", @@ -9799,7 +9789,7 @@ "109312661": "000000000000011100000", "109316086": "000000000000011100000", "109343243": "000000000000011100000", - "109353022": "000000000000011000000", + "109353022": "000000000000011100000", "109358625": "000000000000011100000", "109415962": "000000000000011100000", "109443998": "000000000000011100000", @@ -9850,6 +9840,7 @@ "110547665": "000000000000011100000", "110549479": "000000000000011100000", "110564652": "000000000000011100000", + "110588882": "000000000000011000000", "110625599": "000000000000011100000", "110651452": "000000000000011100000", "110671076": "000000000000011100000", @@ -9943,7 +9934,7 @@ "112615393": "000000000000011100000", "112625134": "000000000000011100000", "112633455": "000000000000011100000", - "112723393": "000000000000011000000", + "112723393": "000000000000011100000", "112744120": "000000000000011100000", "112782614": "000000000000011100000", "112801294": "000000000000011100000", @@ -9975,7 +9966,7 @@ "113370618": "000000000000011100000", "113382312": "000000000000011100000", "113394848": "000000000000011100000", - "113399347": "000000000000011000000", + "113399347": "000000000000011100000", "113424000": "000000000000011100000", "113543502": "000000000000011100000", "113573527": "000000000000011100000", @@ -10056,7 +10047,7 @@ "114816383": "000000000000011100000", "114842356": "000000000000011100000", "114873916": "000000000000011100000", - "114877422": "000000000000011000000", + "114877422": "000000000000011100000", "114884822": "000000000000011100000", "114903095": "000000000000011100000", "114915120": "000000000000011100000", @@ -10116,7 +10107,7 @@ "116072937": "000000000000011100000", "116092235": "000000000000011100000", "116135643": "000000000000011100000", - "116166954": "000000000000011000000", + "116166954": "000000000000011100000", "116167127": "000000000000011100000", "116187693": "000000000000011100000", "116231355": "000000000000011100000", @@ -10133,6 +10124,7 @@ "116392543": "000000000000011100000", "116420265": "000000000000011100000", "116449115": "000000000000011100000", + "116470109": "000000000000011000000", "116479123": "000000000000011100000", "116484261": "000000000000011100000", "116498221": "000000000000011100000", @@ -10148,7 +10140,7 @@ "116584154": "000000000000011100000", "116597879": "000000000000011100000", "116667092": "000000000000011100000", - "116683901": "000000000000011000000", + "116683901": "000000000000011100000", "116704644": "000000000000011100000", "116707794": "000000000000011100000", "116713062": "000000000000011100000", @@ -10186,7 +10178,7 @@ "117323641": "000000000000011100000", "117330258": "000000000000011100000", "117342827": "000000000000011100000", - "117390995": "000000000000011000000", + "117390995": "000000000000011100000", "117435722": "000000000000011100000", "117447583": "000000000000011100000", "117457798": "000000000000011100000", @@ -10224,7 +10216,7 @@ "118062711": "000000000000011100000", "118084366": "000000000000011100000", "118095413": "000000000000011100000", - "118122922": "000000000000011000000", + "118122922": "000000000000011100000", "118150506": "000000000000011100000", "118153774": "000000000000011100000", "118162633": "000000000000011100000", @@ -10253,7 +10245,6 @@ "118594627": "000000000000011100000", "118599251": "000000000000011100000", "118647734": "000000000000011100000", - "118656040": "000000000000010000000", "118667281": "000000000000011100000", "118685761": "000000000000011100000", "118707362": "000000000000011100000", @@ -10261,7 +10252,7 @@ "118789223": "000000000000011100000", "118808671": "000000000000011100000", "118813423": "000000000000011100000", - "118957355": "000000000000011000000", + "118957355": "000000000000011100000", "118969419": "000000000000011100000", "119049126": "000000000000011100000", "119122467": "000000000000011100000", @@ -10277,7 +10268,6 @@ "119340414": "000000000000011100000", "119352533": "000000000000011100000", "119361122": "000000000000011100000", - "119372343": "000000000000010000000", "119380433": "000000000000011100000", "119400640": "000000000000011100000", "119403787": "000000000000011100000", @@ -10303,7 +10293,6 @@ "119733511": "000000000000011100000", "119743391": "000000000000011100000", "119850325": "000000000000011100000", - "119890824": "000000000000010000000", "119895538": "000000000000011100000", "119922337": "000000000000011100000", "119945568": "000000000000011100000", @@ -10318,7 +10307,7 @@ "120204621": "000000000000011100000", "120219676": "000000000000011100000", "120221978": "000000000000011100000", - "120268554": "000000000000011000000", + "120268554": "000000000000011100000", "120277500": "000000000000011100000", "120278139": "000000000000011100000", "120300644": "000000000000011100000", @@ -10348,16 +10337,16 @@ "120655283": "000000000000011100000", "120779173": "000000000000011100000", "120792335": "000000000000011100000", - "120799815": "000000000000011000000", + "120799815": "000000000000011100000", "120810781": "000000000000011100000", "120816722": "000000000000011100000", "120858626": "000000000000011100000", - "120916290": "000000000000010000000", "120922345": "000000000000011100000", "120931229": "000000000000011100000", "120969237": "000000000000011100000", + "121001381": "000000000000011000000", "121066744": "000000000000011100000", - "121090700": "000000000000011000000", + "121090700": "000000000000011100000", "121119558": "000000000000011100000", "121121505": "000000000000011100000", "121137383": "000000000000011100000", @@ -10372,7 +10361,7 @@ "121385225": "000000000000011100000", "121385853": "000000000000011100000", "121397299": "000000000000011100000", - "121436389": "000000000000011000000", + "121436389": "000000000000011100000", "121450455": "000000000000011100000", "121479454": "000000000000011100000", "121525137": "000000000000011100000", @@ -10382,9 +10371,9 @@ "121565955": "000000000000011100000", "121578091": "000000000000011100000", "121579227": "000000000000011100000", - "121579901": "000000000000011000000", + "121579901": "000000000000011100000", "121618864": "000000000000011100000", - "121661340": "000000000000011000000", + "121661340": "000000000000011100000", "121671317": "000000000000011100000", "121677327": "000000000000011100000", "121705294": "000000000000011100000", @@ -10487,7 +10476,7 @@ "124142733": "000000000000011100000", "124154667": "000000000000011100000", "124178496": "000000000000011100000", - "124188255": "000000000000011000000", + "124188255": "000000000000011100000", "124197597": "000000000000011100000", "124232952": "000000000000011100000", "124233544": "000000000000011100000", @@ -10501,7 +10490,7 @@ "124384205": "000000000000011100000", "124405272": "000000000000011100000", "124428403": "000000000000011100000", - "124440602": "000000000000011000000", + "124440602": "000000000000011100000", "124456780": "000000000000011100000", "124474287": "000000000000011100000", "124527239": "000000000000011100000", @@ -10522,6 +10511,7 @@ "124766162": "000000000000011100000", "124816494": "000000000000011100000", "124944756": "000000000000011100000", + "124992020": "000000000000011000000", "125063786": "000000000000011100000", "125064886": "000000000000011100000", "125071816": "000000000000011100000", @@ -10546,7 +10536,7 @@ "125333165": "000000000000011100000", "125335990": "000000000000011100000", "125337472": "000000000000011100000", - "125339827": "000000000000011000000", + "125339827": "000000000000011100000", "125342364": "000000000000011100000", "125347779": "000000000000011100000", "125353034": "000000000000011100000", @@ -10554,7 +10544,7 @@ "125476440": "000000000000011100000", "125486718": "000000000000011100000", "125487695": "000000000000011101000", - "125560140": "000000000000011000000", + "125560140": "000000000000011100000", "125580281": "000000000000011100000", "125601800": "000000000000011100000", "125610640": "000000000000011100000", @@ -10574,14 +10564,14 @@ "125921122": "000000000000011100000", "125953481": "000000000000011100000", "125960050": "000000000000011100000", - "125965258": "000000000000011000000", + "125965258": "000000000000011100000", "126002890": "000000000000011100000", "126021829": "000000000000011100000", "126041567": "000000000000011100000", "126056460": "000000000000011100000", "126058751": "000000000000011100000", "126063227": "000000000000011100000", - "126071363": "000000000000011000000", + "126071363": "000000000000011100000", "126078379": "000000000000011100000", "126114110": "000000000000011100000", "126132225": "000000000000011100000", @@ -10625,7 +10615,6 @@ "127038352": "000000000000011100000", "127050236": "000000000000011100000", "127074219": "000000000000011100000", - "127100158": "000000000000010000000", "127101454": "000000000000011100000", "127119705": "000000000000011100000", "127121827": "000000000000011100000", @@ -10697,9 +10686,9 @@ "128781172": "000000000000011100000", "128806506": "000000000000011100000", "128837592": "000000000000011100000", - "128845305": "000000000000011000000", + "128845305": "000000000000011100000", "128858124": "000000000000011100000", - "128919988": "000000000000011000000", + "128919988": "000000000000011100000", "128923571": "000000000000011100000", "128932297": "000000000000011100000", "128936271": "000000000000011100000", @@ -10729,7 +10718,7 @@ "129378843": "000000000000011100000", "129409748": "000000000000011101000", "129435783": "000000000000011100000", - "129442207": "000000000000011000000", + "129442207": "000000000000011100000", "129443334": "000000000000011100000", "129446709": "000000000000011100000", "129484933": "000000000000011100000", @@ -10743,6 +10732,7 @@ "129643011": "000000000000011100000", "129644570": "000000000000011100000", "129647059": "000000000000011100000", + "129686255": "000000000000011000000", "129696005": "000000000000011100000", "129703235": "000000000000011100000", "129715981": "000000000000011100000", @@ -10870,16 +10860,16 @@ "132602471": "000000000000011100000", "132645663": "000000000000011100000", "132687206": "000000000000011100000", - "132703917": "000000000000011000000", + "132703917": "000000000000011100000", "132722208": "000000000000011100000", "132734796": "000000000000011100000", "132749368": "000000000000011100000", - "132803332": "000000000000011000000", + "132803332": "000000000000011100000", "132817999": "000000000000011100000", "132847975": "000000000000011100000", "132907454": "000000000000011100000", "132966456": "000000000000011100000", - "132974085": "000000000000011000000", + "132974085": "000000000000011100000", "132976113": "000000000000011100000", "132987768": "000000000000011100000", "133002795": "000000000000011100000", @@ -10898,7 +10888,7 @@ "133295674": "000000000000011100000", "133301019": "000000000000011100000", "133311203": "000000000000011100000", - "133317569": "000000000000011000000", + "133317569": "000000000000011100000", "133331838": "000000000000011100000", "133349250": "000000000000011100000", "133373375": "000000000000011100000", @@ -10916,8 +10906,9 @@ "133674117": "000000000000011100000", "133690085": "000000000000011100000", "133690120": "000000000000011100000", + "133695873": "000000000000011000000", "133717153": "000000000000011100000", - "133732882": "000000000000011000000", + "133732882": "000000000000011100000", "133769677": "000000000000011100000", "133783317": "000000000000011100000", "133816002": "000000000000011100000", @@ -10925,7 +10916,7 @@ "133847756": "000000000000011100000", "133855389": "000000000000011100000", "133880829": "000000000000011100000", - "133885973": "000000000000011000000", + "133885973": "000000000000011100000", "133888274": "000000000000011100000", "133915223": "000000000000011100000", "133951501": "000000000000011100000", @@ -10960,9 +10951,9 @@ "134593653": "000000000000011100000", "134675988": "000000000000011100000", "134681250": "000000000000011100000", - "134682782": "000000000000011000000", + "134682782": "000000000000011100000", "134699080": "000000000000011100000", - "134710281": "000000000000011000000", + "134710281": "000000000000011100000", "134722331": "000000000000011100000", "134722988": "000000000000011100000", "134724717": "000000000000011100000", @@ -11008,7 +10999,7 @@ "135172089": "000000000000011100000", "135195225": "000000000000011100000", "135201636": "000000000000011100000", - "135204470": "000000000000011000000", + "135204470": "000000000000011100000", "135250544": "000000000000011100000", "135253386": "000000000000011100000", "135260330": "000000000000011100110", @@ -11029,7 +11020,7 @@ "135543819": "000000000000011100000", "135565012": "000000000000011100000", "135591934": "000000000000011100000", - "135679206": "000000000000011000000", + "135679206": "000000000000011100000", "135694363": "000000000000011100000", "135739928": "000000000000011100000", "135747460": "000000000000011100000", @@ -11044,7 +11035,7 @@ "135923900": "000000000000011100000", "135938663": "000000000000011100000", "136009647": "000000000000011100000", - "136021271": "000000000000011000000", + "136021271": "000000000000011100000", "136024085": "000000000000011100000", "136058606": "000000000000011100000", "136076576": "000000000000011100000", @@ -11087,7 +11078,7 @@ "136778197": "000000000000011100000", "136783924": "000000000000011100000", "136795054": "000000000000011100000", - "136863153": "000000000000011000000", + "136863153": "000000000000011100000", "136930107": "000000000000011100000", "136948998": "000000000000011100000", "136958046": "000000000000011100000", @@ -11111,7 +11102,7 @@ "137282438": "000000000000011100000", "137289065": "000000000000011100000", "137323846": "000000000000011100000", - "137334326": "000000000000011000000", + "137334326": "000000000000011100000", "137349254": "000000000000011100000", "137349302": "000000000000011100000", "137353886": "000000000000011100000", @@ -11124,7 +11115,7 @@ "137497163": "000000000000011100000", "137528721": "000000000000011100000", "137533674": "000000000000011100000", - "137571542": "000000000000011000000", + "137571542": "000000000000011100000", "137597284": "000000000000011100000", "137600388": "000000000000011100000", "137612897": "000000000000011100000", @@ -11134,13 +11125,13 @@ "137774591": "000000000000011100000", "137785955": "000000000000011100000", "137799782": "000000000000011100000", - "137821211": "000000000000011000000", + "137821211": "000000000000011100000", "137856668": "000000000000011100000", "137859935": "000000000000011100000", "137891779": "000000000000011100000", "137891970": "000000000000011100000", "137898876": "000000000000011100000", - "137899639": "000000000000011000000", + "137899639": "000000000000011100000", "137922100": "000000000000011100000", "137932463": "000000000000011100000", "137935203": "000000000000011100000", @@ -11188,7 +11179,7 @@ "139033840": "000000000000011100000", "139061693": "000000000000011100000", "139069948": "000000000000011100000", - "139139294": "000000000000011000000", + "139139294": "000000000000011100000", "139160119": "000000000000011100000", "139170680": "000000000000011100000", "139187383": "000000000000011100000", @@ -11200,12 +11191,11 @@ "139233479": "000000000000011100000", "139237905": "000000000000011100000", "139302848": "000000000000011100000", - "139303060": "000000000000011000000", + "139303060": "000000000000011100000", "139305445": "000000000000011100000", "139331129": "000000000000011100000", "139345368": "000000000000011100000", "139349866": "000000000000011100000", - "139395798": "000000000000010100000", "139405726": "000000000000011100000", "139414022": "000000000000011100000", "139435990": "000000000000011100000", @@ -11229,7 +11219,7 @@ "139836958": "000000000000011100000", "139838248": "000000000000011100000", "139839410": "000000000000011100000", - "139841200": "000000000000011000000", + "139841200": "000000000000011100000", "139862595": "000000000000011100000", "139874718": "000000000000011100000", "139876902": "000000000000011100000", @@ -11250,7 +11240,7 @@ "140275788": "000000000000011100000", "140331056": "000000000000011100000", "140339782": "000000000000011100000", - "140361341": "000000000000011000000", + "140361341": "000000000000011100000", "140380098": "000000000000011100000", "140402451": "000000000000011100000", "140416822": "000000000000011100000", @@ -11377,7 +11367,7 @@ "143328426": "000000000000011100000", "143351556": "000000000000011100000", "143411219": "000000000000011100000", - "143462513": "000000000000011000000", + "143462513": "000000000000011100000", "143471566": "000000000000011100000", "143486434": "000000000000011100000", "143518528": "000000000000011100000", @@ -11426,15 +11416,14 @@ "144435045": "000000000000011100000", "144480498": "000000000000011100000", "144520247": "000000000000011100000", - "144560810": "000000000000010000000", "144595634": "000000000000011100000", "144605783": "000000000000011100000", "144643244": "000000000000011100000", "144683370": "000000000000011100000", "144704313": "000000000000011100000", "144713024": "000000000000011100000", - "144727621": "000000000000011000000", - "144741294": "000000000000011000000", + "144727621": "000000000000011100000", + "144741294": "000000000000011100000", "144742640": "000000000000011100000", "144749311": "000000000000011100000", "144772687": "000000000000011100000", @@ -11473,7 +11462,7 @@ "145481599": "000000000000011100000", "145484743": "000000000000011100000", "145485196": "000000000000011100000", - "145499626": "000000000000011000000", + "145499626": "000000000000011100000", "145506865": "000000000000011100000", "145511911": "000000000000011100000", "145551730": "000000000000011100000", @@ -11514,7 +11503,7 @@ "146381465": "000000000000011100000", "146397841": "000000000000011100000", "146445647": "000000000000011100000", - "146446133": "000000000000011000000", + "146446133": "000000000000011100000", "146456777": "000000000000011100000", "146461255": "000000000000011100000", "146467366": "000000000000011100000", @@ -11613,7 +11602,7 @@ "148395559": "000000000000011100000", "148406210": "000000000000011100000", "148409962": "000000000000011100000", - "148435594": "000000000000011000000", + "148435594": "000000000000011100000", "148451175": "000000000000011100000", "148468902": "000000000000011100000", "148476655": "000000000000011100000", @@ -11651,7 +11640,7 @@ "149108618": "000000000000011100000", "149149582": "000000000000011100000", "149199830": "000000000000011100000", - "149208861": "000000000000011000000", + "149208861": "000000000000011100000", "149209098": "000000000000011100000", "149232703": "000000000000011100000", "149240685": "000000000000011100000", @@ -11660,9 +11649,10 @@ "149358875": "000000000000011100000", "149360875": "000000000000011100000", "149430957": "000000000000011100000", + "149431569": "000000000000011000000", "149464721": "000000000000011100000", "149474295": "000000000000011100000", - "149485357": "000000000000011000000", + "149485357": "000000000000011100000", "149508920": "000000000000011100000", "149511804": "000000000000011100000", "149519300": "000000000000011100000", @@ -11680,7 +11670,7 @@ "149728382": "000000000000011100000", "149778862": "000000000000011100000", "149816083": "000000000000011100000", - "149841870": "000000000000011000000", + "149841870": "000000000000011100000", "149848652": "000000000000011100000", "149866776": "000000000000011100000", "149886718": "000000000000011100000", @@ -11706,7 +11696,7 @@ "150292558": "000000000000011100000", "150294136": "000000000000011100000", "150302848": "000000000000011100000", - "150307412": "000000000000011000000", + "150307412": "000000000000011100000", "150310142": "000000000000011100000", "150317669": "000000000000011100000", "150363242": "000000000000011100000", @@ -11787,8 +11777,8 @@ "151883498": "000000000000011100000", "151894264": "000000000000011100000", "151907483": "000000000000011100000", - "151935008": "000000000000011000000", - "151952251": "000000000000011000000", + "151935008": "000000000000011100000", + "151952251": "000000000000011100000", "151992796": "000000000000011100000", "152000763": "000000000000011100000", "152019675": "000000000000011100000", @@ -11805,14 +11795,14 @@ "152185919": "000000000000011100000", "152221530": "000000000000011100000", "152239679": "000000000000011100000", - "152272742": "000000000000011000000", + "152272742": "000000000000011100000", "152272801": "000000000000011100000", "152290849": "000000000000011100000", "152318820": "000000000000011100000", "152383788": "000000000000011100000", "152403236": "000000000000011100000", "152407452": "000000000000011100000", - "152446032": "000000000000011000000", + "152446032": "000000000000011100000", "152446264": "000000000000011100000", "152452759": "000000000000011100000", "152476982": "000000000000011100000", @@ -11826,7 +11816,7 @@ "152606803": "000000000000011100000", "152623901": "000000000000011100000", "152641244": "000000000000011100000", - "152657193": "000000000000011000000", + "152657193": "000000000000011100000", "152681938": "000000000000011100000", "152707570": "000000000000011100000", "152718090": "000000000000011100000", @@ -11843,7 +11833,7 @@ "152955157": "000000000000011100000", "152964231": "000000000000011100000", "152969033": "000000000000011100000", - "152984112": "000000000000011000000", + "152984112": "000000000000011100000", "152987625": "000000000000011100000", "152993125": "000000000000011100000", "152999471": "000000000000011100000", @@ -11851,7 +11841,7 @@ "153075774": "000000000000011100000", "153087747": "000000000000011100000", "153097532": "000000000000011100000", - "153099234": "000000000000011000000", + "153099234": "000000000000011100000", "153151671": "000000000000011100000", "153156475": "000000000000011100000", "153169579": "000000000000011100000", @@ -11883,7 +11873,7 @@ "153945696": "000000000000011100000", "153980403": "000000000000011100000", "154013804": "000000000000011100000", - "154066600": "000000000000011000000", + "154066600": "000000000000011100000", "154070040": "000000000000011100000", "154108887": "000000000000011100000", "154130946": "000000000000011100000", @@ -11912,7 +11902,7 @@ "154471864": "000000000000011100000", "154479140": "000000000000011100000", "154490916": "000000000000011100000", - "154491294": "000000000000011000000", + "154491294": "000000000000011100000", "154496377": "000000000000011100000", "154503489": "000000000000011100000", "154515453": "000000000000011100000", @@ -11966,7 +11956,7 @@ "155652949": "000000000000011100000", "155655763": "000000000000011100000", "155663660": "000000000000011100000", - "155666063": "000000000000011000000", + "155666063": "000000000000011100000", "155714585": "000000000000011100000", "155755021": "000000000000011100000", "155767738": "000000000000011100000", @@ -11975,7 +11965,7 @@ "155775903": "000000000000011100000", "155777146": "000000000000011100000", "155779656": "000000000000011100000", - "155842050": "000000000000011000000", + "155842050": "000000000000011100000", "155856754": "000000000000011100000", "155902717": "000000000000011100000", "155913345": "000000000000011100000", @@ -11986,7 +11976,7 @@ "155947092": "000000000000011100000", "156065707": "000000000000011100000", "156114259": "000000000000011100000", - "156197505": "000000000000011000000", + "156197505": "000000000000011100000", "156207415": "000000000000011100000", "156234349": "000000000000011100000", "156273935": "000000000000011100000", @@ -11994,7 +11984,7 @@ "156290519": "000000000000011100000", "156292914": "000000000000011100000", "156307864": "000000000000011100000", - "156325584": "000000000000011000000", + "156325584": "000000000000011100000", "156329724": "000000000000011100000", "156349380": "000000000000011100000", "156366554": "000000000000011100000", @@ -12008,7 +11998,7 @@ "156478898": "000000000000011100000", "156509037": "000000000000011100000", "156524320": "000000000000011100000", - "156551738": "000000000000011000000", + "156551738": "000000000000011100000", "156557883": "000000000000011100000", "156567452": "000000000000011100000", "156628068": "000000000000011100000", @@ -12045,7 +12035,7 @@ "157672388": "000000000000011100000", "157682523": "000000000000011100000", "157687285": "000000000000011100000", - "157688210": "000000000000011010000", + "157688210": "000000000000011110000", "157694378": "000000000000011100000", "157705074": "000000000000011100000", "157718795": "000000000000011100000", @@ -12084,10 +12074,9 @@ "158320837": "000000000000011100000", "158403387": "000000000000011100000", "158421462": "000000000000011100000", - "158436215": "000000000000010000000", "158472910": "000000000000011100000", "158496307": "000000000000011100000", - "158525253": "000000000000011000000", + "158525253": "000000000000011100000", "158571348": "000000000000011100000", "158586256": "000000000000011100000", "158609508": "000000000000011100000", @@ -12113,7 +12102,7 @@ "158877135": "000000000000011100000", "158918727": "000000000000011100000", "158927970": "000000000000011100000", - "159077306": "000000000000011000000", + "159077306": "000000000000011100000", "159145218": "000000000000011110000", "159189405": "000000000000011100000", "159213809": "000000000000011100000", @@ -12134,6 +12123,7 @@ "159548315": "000000000000011100000", "159554729": "000000000000011100000", "159556241": "000000000000011100000", + "159569039": "000000000000011000000", "159570309": "000000000000011100000", "159576925": "000000000000011100000", "159600476": "000000000000011100000", @@ -12144,7 +12134,7 @@ "159683049": "000000000000011100000", "159691885": "000000000000011100000", "159715073": "000000000000011100000", - "159723219": "000000000000011000000", + "159723219": "000000000000011100000", "159787019": "000000000000011100000", "159796122": "000000000000011100000", "159808402": "000000000000011100000", @@ -12165,7 +12155,7 @@ "160127278": "000000000000011100000", "160162045": "000000000000011101000", "160171143": "000000000000011100000", - "160244522": "000000000000011000000", + "160244522": "000000000000011100000", "160262608": "000000000000011100000", "160313353": "000000000000011100000", "160324321": "000000000000011100000", @@ -12183,7 +12173,7 @@ "160622326": "000000000000011100000", "160629318": "000000000000011100000", "160670661": "000000000000011100000", - "160677262": "000000000000011000000", + "160677262": "000000000000011100000", "160694480": "000000000000011100000", "160719313": "000000000000011100000", "160830747": "000000000000011100000", @@ -12237,7 +12227,7 @@ "161890688": "000000000000011100000", "161922872": "000000000000011100110", "161951135": "000000000000011100000", - "161952200": "000000000000011000000", + "161952200": "000000000000011100000", "161987471": "000000000000011100000", "162058770": "000000000000011100000", "162098768": "000000000000011100000", @@ -12260,13 +12250,13 @@ "162502777": "000000000000011100000", "162513334": "000000000000011100000", "162533594": "000000000000011100000", - "162540800": "000000000000011000000", + "162540800": "000000000000011100000", "162597487": "000000000000011100000", "162627716": "000000000000011100000", "162642243": "000000000000011100000", "162653003": "000000000000011100000", "162686687": "000000000000011100000", - "162688300": "000000000000011000000", + "162688300": "000000000000011100000", "162728242": "000000000000011100000", "162756142": "000000000000011100000", "162803267": "000000000000011100000", @@ -12340,7 +12330,7 @@ "164720092": "000000000000011100000", "164832723": "000000000000011100000", "164912896": "000000000000011100000", - "164929259": "000000000000011000000", + "164929259": "000000000000011100000", "164933187": "000000000000011100000", "164961410": "000000000000011100000", "165028873": "000000000000011100000", @@ -12362,7 +12352,7 @@ "165361318": "000000000000011100000", "165383766": "000000000000011100000", "165405580": "000000000000011100000", - "165405625": "000000000000011000000", + "165405625": "000000000000011100000", "165408483": "000000000000011100000", "165457464": "000000000000011100000", "165502506": "000000000000011100000", @@ -12403,7 +12393,7 @@ "166283815": "000000000000011100000", "166290956": "000000000000011100000", "166335860": "000000000000011100000", - "166371410": "000000000000011000000", + "166371410": "000000000000011100000", "166379194": "000000000000011100000", "166379738": "000000000000011100000", "166387339": "000000000000011100000", @@ -12414,7 +12404,7 @@ "166418247": "000000000000011100000", "166428174": "000000000000011100000", "166430030": "000000000000011100000", - "166442242": "000000000000011000000", + "166442242": "000000000000011100000", "166461984": "000000000000011100000", "166478151": "000000000000011100000", "166488847": "000000000000011100000", @@ -12441,6 +12431,7 @@ "166941259": "000000000000011100000", "166983997": "000000000000011100000", "167003655": "000000000000011100000", + "167004705": "000000000000011000000", "167013223": "000000000000011100000", "167029272": "000000000000011100000", "167055614": "000000000000011100000", @@ -12479,7 +12470,7 @@ "167796872": "000000000000011100000", "167819234": "000000000000011100000", "167863869": "000000000000011100000", - "167919861": "000000000000011000000", + "167919861": "000000000000011100000", "167921100": "000000000000011100000", "167964053": "000000000000011100000", "167970159": "000000000000011100000", @@ -12523,7 +12514,7 @@ "168638737": "000000000000011100000", "168638815": "000000000000011100000", "168660356": "000000000000011100000", - "168662271": "000000000000011000000", + "168662271": "000000000000011100000", "168685614": "000000000000011100000", "168692081": "000000000000011100000", "168694121": "000000000000011100001", @@ -12551,8 +12542,7 @@ "169223120": "000000000000011100000", "169233397": "000000000000011100000", "169233578": "000000000000011100000", - "169260358": "000000000000011000000", - "169267934": "000000000000010000000", + "169260358": "000000000000011100000", "169271412": "000000000000011100000", "169319989": "000000000000011100000", "169324633": "000000000000011100000", @@ -12570,7 +12560,6 @@ "169502282": "000000000000011100000", "169592494": "000000000000011100000", "169630714": "000000000000011100000", - "169631950": "000000000000010000000", "169658585": "000000000000011100000", "169672925": "000000000000011100000", "169712038": "000000000000011100000", @@ -12628,7 +12617,7 @@ "171091200": "000000000000011100110", "171164714": "000000000000011100000", "171231820": "000000000000011100000", - "171241949": "000000000000011000000", + "171241949": "000000000000011100000", "171249383": "000000000000011100000", "171249838": "000000000000011100000", "171270256": "000000000000011100000", @@ -12799,7 +12788,7 @@ "175152312": "000000000000011100000", "175176776": "000000000000011100000", "175191384": "000000000000011100000", - "175210131": "000000000000011000000", + "175210131": "000000000000011100000", "175264413": "000000000000011100000", "175300921": "000000000000011100000", "175329778": "000000000000011100000", @@ -12859,7 +12848,6 @@ "176418844": "000000000000011100000", "176427605": "000000000000011100000", "176439617": "000000000000011100000", - "176457756": "000000000000010000000", "176522625": "000000000000011100000", "176533225": "000000000000011100000", "176546892": "000000000000011100000", @@ -12926,7 +12914,7 @@ "177759235": "000000000000011100000", "177772134": "000000000000011100000", "177772403": "000000000000011100000", - "177786981": "000000000000011000000", + "177786981": "000000000000011100000", "177823266": "000000000000011100000", "177828699": "000000000000011100000", "177853943": "000000000000011100000", @@ -12943,7 +12931,7 @@ "178140088": "000000000000011100000", "178209105": "000000000000011100000", "178299231": "000000000000011100000", - "178376061": "000000000000011000000", + "178376061": "000000000000011100000", "178381547": "000000000000011100000", "178407933": "000000000000011100000", "178447925": "000000000000011100000", @@ -12954,8 +12942,7 @@ "178555457": "000000000000011100000", "178582559": "000000000000011100000", "178626126": "000000000000011100000", - "178632360": "000000000000011000000", - "178685171": "000000000000010000000", + "178632360": "000000000000011100000", "178686279": "000000000000011100000", "178746189": "000000000000011100000", "178767089": "000000000000011100000", @@ -12994,13 +12981,13 @@ "179476221": "000000000000011100000", "179485588": "000000000000011100000", "179503153": "000000000000011100000", - "179531719": "000000000000011000110", + "179531719": "000000000000011100110", "179541725": "000000000000011100000", "179550028": "000000000000011100000", "179574358": "000000000000011100110", "179587031": "000000000000011100000", "179619588": "000000000000011100000", - "179640723": "000000000000011000000", + "179640723": "000000000000011100000", "179774566": "000000000000011100000", "179805714": "000000000000011100000", "179816276": "000000000000011100000", @@ -13008,7 +12995,6 @@ "179827306": "000000000000011100000", "179849916": "000000000000011100000", "179856128": "000000000000011100000", - "179973687": "000000000000010000000", "179984628": "000000000000011100000", "180016119": "000000000000011100000", "180029425": "000000000000011100000", @@ -13020,7 +13006,7 @@ "180169472": "000000000000011100000", "180170011": "000000000000011100000", "180176674": "000000000000011100000", - "180200895": "000000000000011000000", + "180200895": "000000000000011100000", "180216390": "000000000000011100000", "180227352": "000000000000011100000", "180233814": "000000000000011100000", @@ -13042,7 +13028,7 @@ "180623252": "000000000000011100000", "180642381": "000000000000011100000", "180696674": "000000000000011100000", - "180784821": "000000000000011000000", + "180784821": "000000000000011100000", "180801630": "000000000000011100000", "180844142": "000000000000011100000", "180848418": "000000000000011100000", @@ -13066,7 +13052,6 @@ "181159223": "000000000000011100000", "181161646": "000000000000011100000", "181166241": "000000000000011111000", - "181176947": "000000000000010000000", "181181448": "000000000000011100000", "181187685": "000000000000011100000", "181191906": "000000000000011100000", @@ -13112,7 +13097,7 @@ "182362080": "000000000000011100000", "182396159": "000000000000011100000", "182409200": "000000000000011100000", - "182415525": "000000000000011000000", + "182415525": "000000000000011100000", "182416792": "000000000000011100000", "182442324": "000000000000011100000", "182568781": "000000000000011100000", @@ -13121,7 +13106,7 @@ "182677947": "000000000000011100000", "182681308": "000000000000011100000", "182700538": "000000000000011100000", - "182724340": "000000000000011000000", + "182724340": "000000000000011100000", "182735612": "000000000000011100000", "182744053": "000000000000011100000", "182774018": "000000000000011100000", @@ -13148,7 +13133,7 @@ "183212200": "000000000000011100000", "183229095": "000000000000011100000", "183237883": "000000000000011100000", - "183264888": "000000000000011000000", + "183264888": "000000000000011100000", "183288733": "000000000000011100000", "183339223": "000000000000011100000", "183350487": "000000000000011100000", @@ -13174,7 +13159,7 @@ "183782698": "000000000000011100000", "183787453": "000000000000011100000", "183794868": "000000000000011100000", - "183821743": "000000000000011000000", + "183821743": "000000000000011100000", "183833482": "000000000000011100000", "183860626": "000000000000011100000", "183983301": "000000000000011100000", @@ -13184,6 +13169,7 @@ "184054505": "000000000000011100000", "184064747": "000000000000011100000", "184088126": "000000000000011100000", + "184097217": "000000000000011000000", "184113015": "000000000000011100000", "184127478": "000000000000011100000", "184135291": "000000000000011100000", @@ -13207,7 +13193,7 @@ "184424592": "000000000000011100000", "184426413": "000000000000011100000", "184440742": "000000000000011100000", - "184495374": "000000000000011000000", + "184495374": "000000000000011100000", "184497558": "000000000000011100000", "184522230": "000000000000011100000", "184534133": "000000000000011100000", @@ -13216,7 +13202,7 @@ "184625182": "000000000000011100000", "184625739": "000000000000011100000", "184629353": "000000000000011100000", - "184632342": "000000000000011000000", + "184632342": "000000000000011100000", "184641732": "000000000000011100000", "184648724": "000000000000011100000", "184730551": "000000000000011100000", @@ -13278,10 +13264,10 @@ "185897180": "000000000000011100000", "185950968": "000000000000011100000", "185956469": "000000000000011100000", - "185957199": "000000000000011000000", + "185957199": "000000000000011100000", "185989061": "000000000000011100000", "186014466": "000000000000011100000", - "186050395": "000000000000011000000", + "186050395": "000000000000011100000", "186074065": "000000000000011100000", "186097366": "000000000000011100000", "186141984": "000000000000011100000", @@ -13314,7 +13300,7 @@ "186667132": "000000000000011100000", "186687962": "000000000000011100000", "186700898": "000000000000011100000", - "186755507": "000000000000011000000", + "186755507": "000000000000011100000", "186782723": "000000000000011100000", "186788607": "000000000000011100000", "186897518": "000000000000011100000", @@ -13336,14 +13322,14 @@ "187343038": "000000000000011100000", "187365303": "000000000000011100000", "187382513": "000000000000011100000", - "187382953": "000000000000011000000", + "187382953": "000000000000011100000", "187399458": "000000000000011100000", "187399859": "000000000000011100000", "187415253": "000000000000011100000", "187443351": "000000000000011100000", "187458749": "000000000000011100000", "187488565": "000000000000011100000", - "187492697": "000000000000011000000", + "187492697": "000000000000011100000", "187504422": "000000000000011100000", "187519173": "000000000000011100000", "187547952": "000000000000011100000", @@ -13391,13 +13377,13 @@ "188619959": "000000000000011100000", "188657136": "000000000000011100000", "188732648": "000000000000011100000", - "188735579": "000000000000011000000", + "188735579": "000000000000011100000", "188744383": "000000000000011100000", "188747398": "000000000000011100000", "188840839": "000000000000011100000", "188858037": "000000000000011100000", "188888921": "000000000000011100000", - "188890408": "000000000000011000000", + "188890408": "000000000000011100000", "188891891": "000000000000011100000", "188901547": "000000000000011100000", "188934779": "000000000000011100000", @@ -13507,7 +13493,7 @@ "191473315": "000000000000011100000", "191503592": "000000000000011100000", "191516457": "000000000000011100000", - "191519509": "000000000000011000000", + "191519509": "000000000000011100000", "191685079": "000000000000011100000", "191695850": "000000000000011100000", "191701412": "000000000000011100000", @@ -13596,7 +13582,7 @@ "193425579": "000000000000011100000", "193431875": "000000000000011100000", "193446990": "000000000000011100000", - "193469082": "000000000000011000000", + "193469082": "000000000000011100000", "193510808": "000000000000011100000", "193571736": "000000000000011100000", "193597880": "000000000000011100000", @@ -13604,7 +13590,7 @@ "193601256": "000000000000011100000", "193618796": "000000000000011100000", "193619334": "000000000000011100110", - "193622026": "000000000000011000000", + "193622026": "000000000000011100000", "193635561": "000000000000011100000", "193652057": "000000000000011100000", "193717125": "000000000000011100000", @@ -13651,7 +13637,7 @@ "194620590": "000000000000011100000", "194628760": "000000000000011110000", "194661496": "000000000000011100000", - "194677653": "000000000000011000000", + "194677653": "000000000000011100000", "194695811": "000000000000011100000", "194701362": "000000000000011100000", "194747122": "000000000000011100000", @@ -13661,7 +13647,7 @@ "194829938": "000000000000011100000", "194836812": "000000000000011100000", "194842490": "000000000000011100000", - "194843868": "000000000000011000000", + "194843868": "000000000000011100000", "194890236": "000000000000011100000", "194898855": "000000000000011100000", "194933500": "000000000000011100000", @@ -13673,9 +13659,9 @@ "195030808": "000000000000011100000", "195059108": "000000000000011101000", "195068945": "000000000000011100000", - "195080330": "000000000000011000000", + "195080330": "000000000000011100000", "195089028": "000000000000011100000", - "195089886": "000000000000011000000", + "195089886": "000000000000011100000", "195101960": "000000000000011100000", "195105256": "000000000000011100000", "195113569": "000000000000011100000", @@ -13750,7 +13736,7 @@ "196585194": "000000000000011100000", "196594839": "000000000000011100000", "196596517": "000000000000011100000", - "196649886": "000000000000011000000", + "196649886": "000000000000011100000", "196699219": "000000000000011100000", "196701538": "000000000000011100000", "196724021": "000000000000011100000", @@ -13760,7 +13746,7 @@ "196775163": "000000000000011100000", "196780117": "000000000000011100000", "196784177": "000000000000011100000", - "196786771": "000000000000011000000", + "196786771": "000000000000011100000", "196851025": "000000000000011100000", "196881404": "000000000000011100000", "196883330": "000000000000011100000", @@ -13785,7 +13771,7 @@ "197296103": "000000000000011100000", "197347323": "000000000000011100000", "197394823": "000000000000011100000", - "197408977": "000000000000011000000", + "197408977": "000000000000011100000", "197442782": "000000000000011100000", "197495374": "000000000000011100000", "197508679": "000000000000011100000", @@ -13806,10 +13792,10 @@ "197994251": "000000000000011100000", "198023609": "000000000000011100000", "198024762": "000000000000011100000", - "198044114": "000000000000011000000", + "198044114": "000000000000011100000", "198049321": "000000000000011100000", "198080545": "000000000000011100000", - "198082148": "000000000000011000000", + "198082148": "000000000000011100000", "198132549": "000000000000011100000", "198180650": "000000000000011100000", "198186657": "000000000000011100000", @@ -13942,9 +13928,9 @@ "201602883": "000000000000011100000", "201627986": "000000000000011100000", "201635570": "000000000000011100000", - "201649830": "000000000000011000000", + "201649830": "000000000000011100000", "201657819": "000000000000011100000", - "201666709": "000000000000011000000", + "201666709": "000000000000011100000", "201676251": "000000000000011100000", "201689255": "000000000000011100000", "201690040": "000000000000011100000", @@ -13984,9 +13970,8 @@ "202253969": "000000000000011100000", "202306517": "000000000000011100000", "202310062": "000000000000011100000", - "202317146": "000000000000010000000", "202355314": "000000000000011100000", - "202367228": "000000000000011000000", + "202367228": "000000000000011100000", "202400269": "000000000000011100000", "202401702": "000000000000011100000", "202405215": "000000000000011100000", @@ -13999,7 +13984,7 @@ "202637589": "000000000000011100000", "202678345": "000000000000011100000", "202724141": "000000000000011100000", - "202732335": "000000000000011000000", + "202732335": "000000000000011100000", "202758804": "000000000000011100000", "202773092": "000000000000011100000", "202802618": "000000000000011100000", @@ -14024,7 +14009,7 @@ "203329868": "000000000000011100000", "203354690": "000000000000011100000", "203372708": "000000000000011100000", - "203383082": "000000000000011000000", + "203383082": "000000000000011100000", "203400493": "000000000000011100000", "203447703": "000000000000011100000", "203467076": "000000000000011100000", @@ -14084,10 +14069,11 @@ "204712272": "000000000000011100000", "204749381": "000000000000011100000", "204769344": "000000000000011100000", + "204780382": "000000000000011000000", "204793304": "000000000000011100000", "204803363": "000000000000011100000", "204820325": "000000000000011100000", - "204825745": "000000000000011000000", + "204825745": "000000000000011100000", "204864746": "000000000000011100000", "204873646": "000000000000011100000", "204874257": "000000000000011100000", @@ -14095,12 +14081,12 @@ "204927853": "000000000000011100000", "205022870": "000000000000011100000", "205062732": "000000000000011100000", - "205113063": "000000000000011000000", + "205067579": "000000000000011000000", + "205113063": "000000000000011100000", "205117063": "000000000000011100000", "205133629": "000000000000011100000", "205145220": "000000000000011100000", "205152885": "000000000000011100000", - "205170344": "000000000000010000000", "205174065": "000000000000011100000", "205214521": "000000000000011100000", "205223213": "000000000000011100000", @@ -14126,7 +14112,7 @@ "206022466": "000000000000011100000", "206025128": "000000000000011100000", "206040815": "000000000000011100000", - "206084713": "000000000000011000000", + "206084713": "000000000000011100000", "206116570": "000000000000011100000", "206118412": "000000000000011100000", "206142036": "000000000000011100000", @@ -14164,8 +14150,8 @@ "206675262": "000000000000011100000", "206713738": "000000000000011100000", "206734723": "000000000000011100000", - "206828474": "000000000000011000000", - "206842365": "000000000000011000000", + "206828474": "000000000000011100000", + "206842365": "000000000000011100000", "206861506": "000000000000011100000", "206913808": "000000000000011100000", "206915402": "000000000000011100000", @@ -14239,12 +14225,13 @@ "208289325": "000000000000011100000", "208294775": "000000000000011100000", "208321485": "000000000000011100000", - "208352898": "000000000000011000000", + "208352898": "000000000000011100000", "208363299": "000000000000011100000", "208393308": "000000000000011100000", "208459023": "000000000000011100000", "208465005": "000000000000011100000", "208494892": "000000000000011100000", + "208518909": "000000000000011000000", "208529315": "000000000000011100000", "208539033": "000000000000011100000", "208564133": "000000000000011100000", @@ -14259,7 +14246,7 @@ "208893852": "000000000000011100000", "208900253": "000000000000011100000", "208950563": "000000000000011100000", - "208954486": "000000000000011000000", + "208954486": "000000000000011100000", "208963212": "000000000000011100000", "208986051": "000000000000011100000", "209082858": "000000000000011100000", @@ -14285,7 +14272,7 @@ "209506525": "000000000000011100000", "209511439": "000000000000011100000", "209521252": "000000000000011100000", - "209522459": "000000000000011000000", + "209522459": "000000000000011100000", "209593534": "000000000000011100000", "209615164": "000000000000011100000", "209628531": "000000000000011100000", @@ -14348,14 +14335,14 @@ "211215484": "000000000000011100000", "211221697": "000000000000011100000", "211236477": "000000000000011100000", - "211241247": "000000000000011000000", + "211241247": "000000000000011100000", "211247361": "000000000000011100000", "211273594": "000000000000011100000", "211300798": "000000000000011100000", "211303551": "000000000000011100000", "211315596": "000000000000011100000", "211345946": "000000000000011100000", - "211385430": "000000000000011000000", + "211385430": "000000000000011100000", "211390993": "000000000000011100000", "211391838": "000000000000011100000", "211394078": "000000000000011100000", @@ -14382,7 +14369,7 @@ "211876797": "000000000000011100000", "211890133": "000000000000011100000", "211910362": "000000000000011100000", - "211934537": "000000000000011000000", + "211934537": "000000000000011100000", "211939315": "000000000000011100000", "211941015": "000000000000011100000", "211957831": "000000000000011100000", @@ -14417,6 +14404,7 @@ "212811028": "000000000000011100000", "212822069": "000000000000011100000", "212846507": "000000000000011100000", + "212864561": "000000000000011000000", "212872113": "000000000000011100000", "212877751": "000000000000011100000", "212920318": "000000000000011100000", @@ -14430,9 +14418,10 @@ "213078478": "000000000000011100000", "213094986": "000000000000011100000", "213097487": "000000000000011100000", + "213134157": "000000000000011000000", "213141333": "000000000000011100000", "213144447": "000000000000011100000", - "213174008": "000000000000011000000", + "213174008": "000000000000011100000", "213200184": "000000000000011100000", "213201397": "000000000000011100000", "213202161": "000000000000011100000", @@ -14441,7 +14430,7 @@ "213229378": "000000000000011100000", "213237204": "000000000000011100000", "213260374": "000000000000011100000", - "213350749": "000000000000011000000", + "213350749": "000000000000011100000", "213371968": "000000000000011100000", "213400233": "000000000000011100000", "213405571": "000000000000011100000", @@ -14460,7 +14449,7 @@ "213724787": "000000000000011100000", "213787953": "000000000000011100000", "213823167": "000000000000011100000", - "213868092": "000000000000011000000", + "213868092": "000000000000011100000", "213906915": "000000000000011100000", "213972221": "000000000000011100000", "214000850": "000000000000011101000", @@ -14577,7 +14566,7 @@ "216412167": "000000000000011100000", "216422520": "000000000000011100000", "216459598": "000000000000011100000", - "216472639": "000000000000011000000", + "216472639": "000000000000011100000", "216483114": "000000000000011100000", "216530715": "000000000000011100000", "216546456": "000000000000011100000", @@ -14588,7 +14577,7 @@ "216702458": "000000000000011100000", "216728328": "000000000000011100000", "216748548": "000000000000011100000", - "216755609": "000000000000011000000", + "216755609": "000000000000011100000", "216762302": "000000000000011100000", "216773965": "000000000000011100000", "216790008": "000000000000011100000", @@ -14600,11 +14589,11 @@ "217086733": "000000000000011100000", "217118702": "000000000000011100000", "217161171": "000000000000011100000", - "217186450": "000000000000011000000", + "217186450": "000000000000011100000", "217208526": "000000000000011100000", "217214194": "000000000000011100000", "217225999": "000000000000011100000", - "217232583": "000000000000011000000", + "217232583": "000000000000011100000", "217273022": "000000000000011100000", "217296572": "000000000000011100000", "217301605": "000000000000011100110", @@ -14634,6 +14623,7 @@ "217908649": "000000000000011100000", "217918438": "000000000000011100000", "217982856": "000000000000011100000", + "218094547": "000000000000011000000", "218116209": "000000000000011100000", "218121943": "000000000000011100000", "218154236": "000000000000011100000", @@ -14647,9 +14637,8 @@ "218265185": "000000000000011100000", "218285267": "000000000000011100000", "218322829": "000000000000011100000", - "218342903": "000000000000011000000", + "218342903": "000000000000011100000", "218385725": "000000000000011100000", - "218389449": "000000000000010000000", "218447108": "000000000000011100000", "218448550": "000000000000011100000", "218449155": "000000000000011100000", @@ -14663,7 +14652,7 @@ "218654399": "000000000000011100000", "218667142": "000000000000011100000", "218689097": "000000000000011100000", - "218726533": "000000000000011000000", + "218726533": "000000000000011100000", "218728554": "000000000000011100000", "218751822": "000000000000011100000", "218751961": "000000000000011100000", @@ -14691,7 +14680,7 @@ "219193224": "000000000000011100000", "219230371": "000000000000011100000", "219236292": "000000000000011100000", - "219241035": "000000000000011000000", + "219241035": "000000000000011100000", "219244522": "000000000000011100000", "219289273": "000000000000011100000", "219300916": "000000000000011100000", @@ -14716,7 +14705,7 @@ "219928114": "000000000000011100000", "219947090": "000000000000011100000", "219951004": "000000000000011100000", - "219951409": "000000000000011000000", + "219951409": "000000000000011100000", "219990149": "000000000000011100000", "219994623": "000000000000011100000", "220011344": "000000000000011100000", @@ -14732,7 +14721,7 @@ "220232499": "000000000000011100000", "220244825": "000000000000011100000", "220301925": "000000000000011100000", - "220312826": "000000000000011000000", + "220312826": "000000000000011100000", "220388193": "000000000000011100000", "220435370": "000000000000011100000", "220480083": "000000000000011100000", @@ -14757,7 +14746,7 @@ "220783242": "000000000000011100000", "220786970": "000000000000011100000", "220813548": "000000000000011100000", - "220856896": "000000000000011000000", + "220856896": "000000000000011100000", "220866804": "000000000000011100000", "220914616": "000000000000011100000", "220933197": "000000000000011100000", @@ -14812,8 +14801,9 @@ "222176969": "000000000000011100000", "222264357": "000000000000011100000", "222286575": "000000000000011100000", + "222309678": "000000000000011000000", "222318437": "000000000000011100000", - "222341526": "000000000000011000000", + "222341526": "000000000000011100000", "222361609": "000000000000011100000", "222363671": "000000000000011100000", "222369477": "000000000000011100000", @@ -14851,7 +14841,7 @@ "223033557": "000000000000011100000", "223079578": "000000000000011100000", "223086822": "000000000000011100000", - "223117672": "000000000000011000000", + "223117672": "000000000000011100000", "223139347": "000000000000011100000", "223140763": "000000000000011100000", "223147163": "000000000000011100000", @@ -14860,7 +14850,6 @@ "223223760": "000000000000011100000", "223227804": "000000000000011100000", "223241479": "000000000000011100000", - "223258193": "000000000000010000000", "223270724": "000000000000011100000", "223290854": "000000000000011100000", "223307194": "000000000000011100000", @@ -14922,8 +14911,8 @@ "224649953": "000000000000011100000", "224650578": "000000000000011100000", "224668429": "000000000000011100000", - "224679586": "000000000000011000000", - "224776588": "000000000000011000000", + "224679586": "000000000000011100000", + "224776588": "000000000000011100000", "224786882": "000000000000011100000", "224792250": "000000000000011100000", "224799218": "000000000000011100000", @@ -14972,6 +14961,7 @@ "225694844": "000000000000011100000", "225695020": "000000000000011100000", "225701017": "000000000000011100000", + "225705746": "000000000000011000000", "225748608": "000000000000011100000", "225806114": "000000000000011100000", "225817196": "000000000000011100000", @@ -15055,13 +15045,13 @@ "227164577": "000000000000011100000", "227165228": "000000000000011100000", "227226987": "000000000000011100000", - "227230202": "000000000000011000000", + "227230202": "000000000000011100000", "227318824": "000000000000011100000", "227343725": "000000000000011100000", "227354466": "000000000000011100000", "227416673": "000000000000011100000", "227417076": "000000000000011100000", - "227442325": "000000000000011000110", + "227442325": "000000000000011100110", "227515649": "000000000000011100000", "227516137": "000000000000011100000", "227580028": "000000000000011100000", @@ -15112,7 +15102,7 @@ "228561537": "000000000000011100000", "228566553": "000000000000011100000", "228604622": "000000000000011100000", - "228623702": "000000000000011000000", + "228623702": "000000000000011100000", "228630603": "000000000000011100000", "228644595": "000000000000011100000", "228664063": "000000000000011100000", @@ -15140,6 +15130,7 @@ "229093626": "000000000000011100000", "229095494": "000000000000011100000", "229120509": "000000000000011100000", + "229142859": "000000000000011000000", "229158349": "000000000000011100000", "229177013": "000000000000011100000", "229184200": "000000000000011100000", @@ -15154,7 +15145,7 @@ "229292294": "000000000000011100000", "229320529": "000000000000011100000", "229324031": "000000000000011100000", - "229340426": "000000000000011000000", + "229340426": "000000000000011100000", "229364352": "000000000000011100000", "229393373": "000000000000011100000", "229436869": "000000000000011100000", @@ -15233,9 +15224,10 @@ "230900940": "000000000000011100000", "230931594": "000000000000011100000", "230955786": "000000000000011100000", - "230961718": "000000000000011000000", + "230961718": "000000000000011100000", "230963944": "000000000000011100000", "230966619": "000000000000011100000", + "230972485": "000000000000011000000", "230990026": "000000000000011100000", "231006620": "000000000000011100000", "231011904": "000000000000011100000", @@ -15299,7 +15291,7 @@ "232291898": "000000000000011100000", "232299760": "000000000000011100000", "232350985": "000000000000011100000", - "232355513": "000000000000011000000", + "232355513": "000000000000011100000", "232376996": "000000000000011100000", "232411707": "000000000000011100000", "232411977": "000000000000011100000", @@ -15321,7 +15313,7 @@ "232956613": "000000000000011100000", "232998270": "000000000000011100000", "233010730": "000000000000011100000", - "233029364": "000000000000011000000", + "233029364": "000000000000011100000", "233046680": "000000000000011100000", "233050631": "000000000000011100000", "233057043": "000000000000011100000", @@ -15347,7 +15339,7 @@ "233418614": "000000000000011100000", "233451164": "000000000000011101000", "233474984": "000000000000011100000", - "233479080": "000000000000011000000", + "233479080": "000000000000011100000", "233487725": "000000000000011100000", "233492087": "000000000000011100000", "233522030": "000000000000011100000", @@ -15384,7 +15376,7 @@ "234353547": "000000000000011100000", "234358600": "000000000000011100000", "234379325": "000000000000011100000", - "234418283": "000000000000011000000", + "234418283": "000000000000011100000", "234419922": "000000000000011100000", "234429898": "000000000000011100000", "234477518": "000000000000011100000", @@ -15457,7 +15449,7 @@ "235745584": "000000000000011100000", "235750535": "000000000000011100000", "235770429": "000000000000011100000", - "235828808": "000000000000011000000", + "235828808": "000000000000011100000", "235865650": "000000000000011100000", "235880132": "000000000000011100000", "235888784": "000000000000011100000", @@ -15512,7 +15504,7 @@ "236793710": "000000000000011100000", "236797420": "000000000000011100000", "236811087": "000000000000011100000", - "236830556": "000000000000011000000", + "236830556": "000000000000011100000", "236836957": "000000000000011100000", "236837575": "000000000000011100000", "236851524": "000000000000011100000", @@ -15548,10 +15540,10 @@ "237451665": "000000000000011100000", "237471157": "000000000000011100000", "237473577": "000000000000011100000", - "237499433": "000000000000011000000", + "237499433": "000000000000011100000", "237525357": "000000000000011100000", "237546320": "000000000000011100000", - "237554954": "000000000000011000000", + "237554954": "000000000000011100000", "237625515": "000000000000011100000", "237630161": "000000000000011100000", "237631795": "000000000000011100000", @@ -15564,14 +15556,14 @@ "237759583": "000000000000011100000", "237765183": "000000000000011100000", "237774498": "000000000000011100000", - "237802863": "000000000000011000000", + "237802863": "000000000000011100000", "237809328": "000000000000011100000", "237837943": "000000000000011100000", "237907798": "000000000000011100000", "237982192": "000000000000011100000", "238019981": "000000000000011100000", "238110949": "000000000000011100000", - "238115316": "000000000000011000000", + "238115316": "000000000000011100000", "238117340": "000000000000011100000", "238131100": "000000000000011100000", "238152951": "000000000000011100000", @@ -15592,7 +15584,6 @@ "238527530": "000000000000011100000", "238580102": "000000000000011100000", "238587993": "000000000000011100000", - "238593185": "000000000000010000000", "238614092": "000000000000011100000", "238618016": "000000000000011100000", "238635031": "000000000000011100000", @@ -15684,7 +15675,6 @@ "240444422": "000000000000011100000", "240464373": "000000000000011100000", "240483551": "000000000000011100000", - "240529529": "000000000000010000110", "240558845": "000000000000011100000", "240560563": "000000000000011100000", "240566552": "000000000000011100000", @@ -15727,7 +15717,7 @@ "241399159": "000000000000011100000", "241432149": "000000000000011100000", "241442715": "000000000000011100000", - "241456544": "000000000000011000000", + "241456544": "000000000000011100000", "241473426": "000000000000011100000", "241475751": "000000000000011100000", "241492094": "000000000000011100000", @@ -15760,7 +15750,7 @@ "242132021": "000000000000011100000", "242155723": "000000000000011100000", "242161182": "000000000000011100000", - "242183810": "000000000000011000000", + "242183810": "000000000000011100000", "242193937": "000000000000011100000", "242227070": "000000000000011100000", "242244601": "000000000000011100000", @@ -15773,7 +15763,7 @@ "242477270": "000000000000011100000", "242547471": "000000000000011100000", "242554089": "000000000000011100000", - "242554177": "000000000000011000000", + "242554177": "000000000000011100000", "242555963": "000000000000011100000", "242556607": "000000000000011100000", "242592613": "000000000000011100000", @@ -15786,7 +15776,7 @@ "242697131": "000000000000011100000", "242730782": "000000000000011100000", "242777429": "000000000000011100000", - "242791329": "000000000000011000000", + "242791329": "000000000000011100000", "242799485": "000000000000011100000", "242800516": "000000000000011100000", "242828953": "000000000000011100000", @@ -15797,6 +15787,7 @@ "243036684": "000000000000011100000", "243069274": "000000000000011100000", "243083631": "000000000000011100000", + "243095164": "000000000000011000000", "243118113": "000000000000011100000", "243145867": "000000000000011100000", "243153605": "000000000000011100000", @@ -15849,7 +15840,7 @@ "244097534": "000000000000011100000", "244152611": "000000000000011100000", "244165140": "000000000000011100000", - "244177216": "000000000000011000000", + "244177216": "000000000000011100000", "244188896": "000000000000011100000", "244199339": "000000000000011100000", "244227847": "000000000000011100000", @@ -15859,9 +15850,10 @@ "244319893": "000000000000011100110", "244342660": "000000000000011100000", "244345506": "000000000000011100000", - "244367609": "000000000000011000000", + "244367609": "000000000000011100000", "244400151": "000000000000011100000", "244436548": "000000000000011100000", + "244443082": "000000000000011000000", "244466890": "000000000000011100000", "244485668": "000000000000011100000", "244496042": "000000000000011100000", @@ -15878,6 +15870,7 @@ "244949329": "000000000000011100000", "244962843": "000000000000011100000", "244964715": "000000000000011100000", + "244971338": "000000000000011000000", "244979020": "000000000000011100000", "245006167": "000000000000011100000", "245008798": "000000000000011100000", @@ -15888,7 +15881,7 @@ "245090337": "000000000000011100000", "245107509": "000000000000011100000", "245132281": "000000000000011100000", - "245142253": "000000000000011000000", + "245142253": "000000000000011100000", "245148634": "000000000000011100000", "245186846": "000000000000011100000", "245189579": "000000000000011100000", @@ -15913,7 +15906,6 @@ "245681471": "000000000000011100000", "245689306": "000000000000011100000", "245691816": "000000000000011100000", - "245712397": "000000000000010000000", "245720594": "000000000000011100000", "245744267": "000000000000011100000", "245765506": "000000000000011100000", @@ -15926,7 +15918,7 @@ "245908368": "000000000000011100000", "246034344": "000000000000011100000", "246062204": "000000000000011100000", - "246065447": "000000000000011000000", + "246065447": "000000000000011100000", "246101400": "000000000000011100000", "246103649": "000000000000011100000", "246108899": "000000000000011100000", @@ -15944,7 +15936,7 @@ "246337348": "000000000000011100000", "246337555": "000000000000011100000", "246338674": "000000000000011100000", - "246340562": "000000000000011010000", + "246340562": "000000000000011110000", "246342308": "000000000000011100000", "246343551": "000000000000011100000", "246348443": "000000000000011100000", @@ -15953,7 +15945,7 @@ "246470557": "000000000000011100000", "246513294": "000000000000011100000", "246522548": "000000000000011100000", - "246557029": "000000000000011000000", + "246557029": "000000000000011100000", "246577579": "000000000000011100000", "246584232": "000000000000011100000", "246594178": "000000000000011100000", @@ -15997,7 +15989,7 @@ "247747808": "000000000000011100000", "247776250": "000000000000011110000", "247820194": "000000000000011100000", - "247824788": "000000000000011000000", + "247824788": "000000000000011100000", "247850531": "000000000000011100000", "247864912": "000000000000011100000", "247869115": "000000000000011100000", @@ -16076,7 +16068,7 @@ "249454210": "000000000000011110000", "249477488": "000000000000011100000", "249501561": "000000000000011100000", - "249528760": "000000000000011000110", + "249528760": "000000000000011100110", "249615847": "000000000000011100000", "249618701": "000000000000011100000", "249658317": "000000000000011100000", @@ -16112,7 +16104,7 @@ "250411692": "000000000000011100000", "250426832": "000000000000011100000", "250470985": "000000000000011100000", - "250486168": "000000000000011000000", + "250486168": "000000000000011100000", "250498299": "000000000000011100000", "250517377": "000000000000011100000", "250542066": "000000000000011100000", @@ -16126,14 +16118,14 @@ "250712050": "000000000000011100000", "250716711": "000000000000011100000", "250720220": "000000000000011100000", - "250732650": "000000000000011000000", + "250732650": "000000000000011100000", "250736001": "000000000000011100000", "250759631": "000000000000011100000", "250771648": "000000000000011100000", "250789248": "000000000000011100000", "250817909": "000000000000011100000", "250820781": "000000000000011100000", - "250865418": "000000000000011000000", + "250865418": "000000000000011100000", "250874622": "000000000000011100000", "250898525": "000000000000011100000", "250900179": "000000000000011100000", @@ -16144,20 +16136,20 @@ "251027292": "000000000000011100000", "251032858": "000000000000011100000", "251073164": "000000000000011100000", + "251094567": "000000000000011000000", "251098080": "000000000000011100000", "251102116": "000000000000011100000", "251140530": "000000000000011100000", "251190159": "000000000000011100000", "251217505": "000000000000011100000", - "251224389": "000000000000010000000", - "251250009": "000000000000011000000", + "251250009": "000000000000011100000", "251282711": "000000000000011100000", "251283358": "000000000000011100000", "251303090": "000000000000011100000", "251333671": "000000000000011100000", "251361818": "000000000000011100000", "251377191": "000000000000011100000", - "251389946": "000000000000011000000", + "251389946": "000000000000011100000", "251436769": "000000000000011100000", "251437684": "000000000000011100000", "251484588": "000000000000011100000", @@ -16170,7 +16162,7 @@ "251596495": "000000000000011100000", "251668489": "000000000000011100000", "251767906": "000000000000011100000", - "251769146": "000000000000011000000", + "251769146": "000000000000011100000", "251807740": "000000000000011100000", "251833982": "000000000000011100000", "251839317": "000000000000011100000", @@ -16227,9 +16219,9 @@ "252909597": "000000000000011100000", "252947754": "000000000000011100000", "252972950": "000000000000011100000", - "252987998": "000000000000011000000", + "252987998": "000000000000011100000", "252996188": "000000000000011100000", - "253001878": "000000000000011001000", + "253001878": "000000000000011101000", "253003743": "000000000000011100000", "253005180": "000000000000011100000", "253023099": "000000000000011100000", @@ -16247,8 +16239,7 @@ "253282419": "000000000000011100000", "253311904": "000000000000011100000", "253314808": "000000000000011100000", - "253318345": "000000000000010000000", - "253338336": "000000000000011000000", + "253338336": "000000000000011100000", "253363555": "000000000000011100000", "253377522": "000000000000011100000", "253395081": "000000000000011100000", @@ -16317,7 +16308,6 @@ "255009042": "000000000000011100000", "255026329": "000000000000011100000", "255037516": "000000000000011100000", - "255045879": "000000000000010000000", "255052807": "000000000000011100000", "255082626": "000000000000011100000", "255087360": "000000000000011100000", @@ -16397,7 +16387,7 @@ "256640209": "000000000000011100000", "256646324": "000000000000011100000", "256726154": "000000000000011100000", - "256728698": "000000000000011000000", + "256728698": "000000000000011100000", "256778629": "000000000000011100000", "256792277": "000000000000011100000", "256797304": "000000000000011100000", @@ -16427,7 +16417,7 @@ "257213156": "000000000000011100000", "257226573": "000000000000011100000", "257239866": "000000000000011100000", - "257248214": "000000000000011000000", + "257248214": "000000000000011100000", "257337087": "000000000000011100000", "257377001": "000000000000011100000", "257382313": "000000000000011100000", @@ -16444,7 +16434,7 @@ "257704877": "000000000000011100000", "257715163": "000000000000011100000", "257756324": "000000000000011100000", - "257757962": "000000000000011000000", + "257757962": "000000000000011100000", "257783038": "000000000000011100110", "257819856": "000000000000011100000", "257840292": "000000000000011100000", @@ -16462,7 +16452,7 @@ "258126381": "000000000000011100000", "258184889": "000000000000011100000", "258212918": "000000000000011100000", - "258252763": "000000000000011000000", + "258252763": "000000000000011100000", "258254948": "000000000000011100000", "258267794": "000000000000011100110", "258272478": "000000000000011100000", @@ -16489,6 +16479,7 @@ "258596787": "000000000000011100000", "258625309": "000000000000011100000", "258662200": "000000000000011100000", + "258686211": "000000000000011000000", "258700837": "000000000000011100000", "258740473": "000000000000011100000", "258754098": "000000000000011100000", @@ -16532,9 +16523,9 @@ "259846489": "000000000000011100000", "259857248": "000000000000011100000", "259866017": "000000000000011100000", - "259890144": "000000000000011000000", + "259890144": "000000000000011100000", "259892328": "000000000000011100000", - "259900392": "000000000000011000000", + "259900392": "000000000000011100000", "259904661": "000000000000011100000", "259909252": "000000000000011100000", "259925884": "000000000000011100000", @@ -16669,7 +16660,7 @@ "262778541": "000000000000011100000", "262782640": "000000000000011100000", "262794978": "000000000000011100000", - "262922782": "000000000000011000000", + "262922782": "000000000000011100000", "262929002": "000000000000011100000", "262936407": "000000000000011100000", "262955982": "000000000000011100000", @@ -16728,7 +16719,7 @@ "264066209": "000000000000011100000", "264096811": "000000000000011100000", "264118232": "000000000000011100000", - "264133140": "000000000000011000000", + "264133140": "000000000000011100000", "264174688": "000000000000011100000", "264194948": "000000000000011100000", "264249580": "000000000000011100000", @@ -16776,7 +16767,7 @@ "265387623": "000000000000011100000", "265438602": "000000000000011100000", "265454010": "000000000000011100000", - "265503718": "000000000000011000000", + "265503718": "000000000000011100000", "265545534": "000000000000011100000", "265580038": "000000000000011100000", "265601962": "000000000000011100000", @@ -16790,10 +16781,11 @@ "265818035": "000000000000011100000", "265852023": "000000000000011100000", "265853129": "000000000000011100000", + "265864283": "000000000000011000000", "265876469": "000000000000011100000", "265885480": "000000000000011100000", "265897145": "000000000000011100000", - "265911929": "000000000000011000000", + "265911929": "000000000000011100000", "265966880": "000000000000011100000", "265967560": "000000000000011100000", "265985740": "000000000000011100000", @@ -16900,415 +16892,51 @@ "268385106": "000000000000011100000", "268393112": "000000000000011100000", "268404793": "000000000000011100000", - "7221347": "000000000000001100000", - "18440025": "000000000000001100000", - "34234277": "000000000000001100000", - "45847456": "000000000000001100000", - "49191733": "000000000000001100000", - "51768546": "000000000000001100000", - "85080806": "000000000000001100000", - "86153616": "000000000000001100000", - "90460966": "000000000000001100000", - "96998652": "000000000000001100000", - "101743985": "000000000000001100000", - "110588882": "000000000000001100000", - "116470109": "000000000000001100000", - "121001381": "000000000000001100000", - "124992020": "000000000000001100000", - "129686255": "000000000000001100000", - "133695873": "000000000000001100000", - "149431569": "000000000000001100000", - "159569039": "000000000000001100000", - "167004705": "000000000000001100000", - "184097217": "000000000000001100000", - "204780382": "000000000000001100000", - "205067579": "000000000000001000000", - "208518909": "000000000000001100000", - "212864561": "000000000000001100000", - "213134157": "000000000000001100000", - "218094547": "000000000000001100000", - "222309678": "000000000000001100000", - "225705746": "000000000000001100000", - "229142859": "000000000000001100000", - "230972485": "000000000000001100000", - "243095164": "000000000000001100000", - "244443082": "000000000000001100000", - "244971338": "000000000000001100000", - "251094567": "000000000000001100000", - "258686211": "000000000000001100000", - "265864283": "000000000000001100000", - "591090": "000000000000000100000", - "1114215": "000000000000000100000", - "1475319": "000000000000000100000", - "1553353": "000000000000000100000", - "1755583": "000000000000000100000", - "3895417": "000000000000000100000", - "4771259": "000000000000000100000", - "4990438": "000000000000000100000", - "4992656": "000000000000000100000", - "5399635": "000000000000000100000", - "5888542": "000000000000000100000", - "7405326": "000000000000000100000", - "9396487": "000000000000000100000", - "9417616": "000000000000000100000", - "9821757": "000000000000000100000", - "10152664": "000000000000000100000", - "10261280": "000000000000000100000", - "10781859": "000000000000000100000", - "11494443": "000000000000000100000", - "13447663": "000000000000000100000", - "14108794": "000000000000000100000", - "14721979": "000000000000000100000", - "15119354": "000000000000000100000", - "17327880": "000000000000000100000", - "17375520": "000000000000000100000", - "17530971": "000000000000000100000", - "17578826": "000000000000000100000", - "17683340": "000000000000000100000", - "17900263": "000000000000000100000", - "18686811": "000000000000000100000", - "19859444": "000000000000000100000", - "19966149": "000000000000000100000", - "20261345": "000000000000000100000", - "21343219": "000000000000000100000", - "21610623": "000000000000000100000", - "21823530": "000000000000000100000", - "23015303": "000000000000000100000", - "23609308": "000000000000000100000", - "24680864": "000000000000000100000", - "27528422": "000000000000000100000", - "27994071": "000000000000000100000", - "29506156": "000000000000000100000", - "31238096": "000000000000000100000", - "31586296": "000000000000000100000", - "31868645": "000000000000000100000", - "31943334": "000000000000000100000", - "32598544": "000000000000000100000", - "33100264": "000000000000000100000", - "35625710": "000000000000000100000", - "35971688": "000000000000000100000", - "35990481": "000000000000000100000", - "36070606": "000000000000000100000", - "38198010": "000000000000000100000", - "38243995": "000000000000000100000", - "38403670": "000000000000000100000", - "38810138": "000000000000000100000", - "39672220": "000000000000000100000", - "40470315": "000000000000000100000", - "41436956": "000000000000000100000", - "42759003": "000000000000000100000", - "43703499": "000000000000000100001", - "44570122": "000000000000000100000", - "44853821": "000000000000000100000", - "45028931": "000000000000000100000", - "45257729": "000000000000000100000", - "45955327": "000000000000000100000", - "46012016": "000000000000000100000", - "46312030": "000000000000000100000", - "46871922": "000000000000000100000", - "47831535": "000000000000000100000", - "48111710": "000000000000000100000", - "48817275": "000000000000000100000", - "49375680": "000000000000000100000", - "50250307": "000000000000000100000", - "51579284": "000000000000000100000", - "51967817": "000000000000000100000", - "52336344": "000000000000000100000", - "52603625": "000000000000000100000", - "52679997": "000000000000000100000", - "52889495": "000000000000000100000", - "53022389": "000000000000000100000", - "53753283": "000000000000000100000", - "53858994": "000000000000000100000", - "56198528": "000000000000000100000", - "56419947": "000000000000000100000", - "56752481": "000000000000000100000", - "56956950": "000000000000000100000", - "57033887": "000000000000000100000", - "57457475": "000000000000000100000", - "57916350": "000000000000000100000", - "57921094": "000000000000000100000", - "59340275": "000000000000000100000", - "59471352": "000000000000000100000", - "62148956": "000000000000000100000", - "62676230": "000000000000000100000", - "63700259": "000000000000000101000", - "65791858": "000000000000000100000", - "66188293": "000000000000000100000", - "66201360": "000000000000000100000", - "67061686": "000000000000000100000", - "67281281": "000000000000000100000", - "68020233": "000000000000000100000", - "68147131": "000000000000000100000", - "68159916": "000000000000000100000", - "68306755": "000000000000000100000", - "68504585": "000000000000000100000", - "69936759": "000000000000000100000", - "70030113": "000000000000000100000", - "70674626": "000000000000000100000", - "71362929": "000000000000000100000", - "72289401": "000000000000000100000", - "72693488": "000000000000000100000", - "74304645": "000000000000000100000", - "74517543": "000000000000000100000", - "74778247": "000000000000000100000", - "75323625": "000000000000000100000", - "77557878": "000000000000000100000", - "77938075": "000000000000000100000", - "79184778": "000000000000000100000", - "79218441": "000000000000000100110", - "79938627": "000000000000000100000", - "80324463": "000000000000000100000", - "80720804": "000000000000000100000", - "80816163": "000000000000000100000", - "80820065": "000000000000000100000", - "80996391": "000000000000000100000", - "83343691": "000000000000000100000", - "83421637": "000000000000000100000", - "84325998": "000000000000000100000", - "84673861": "000000000000000100000", - "85094129": "000000000000000100000", - "85292039": "000000000000000100000", - "86326212": "000000000000000100000", - "87516162": "000000000000000100000", - "87996519": "000000000000000100000", - "89724789": "000000000000000100000", - "90043425": "000000000000000100000", - "90758047": "000000000000000100000", - "91291736": "000000000000000100000", - "92715468": "000000000000000100000", - "92861645": "000000000000000100000", - "94684306": "000000000000000100000", - "95797674": "000000000000000100000", - "96564640": "000000000000000100000", - "96709179": "000000000000000100000", - "98276734": "000000000000000100000", - "98703619": "000000000000000100000", - "98876195": "000000000000000100000", - "99073383": "000000000000000100000", - "99317761": "000000000000000100000", - "99995532": "000000000000000100000", - "100901623": "000000000000000100000", - "101446381": "000000000000000100000", - "103303670": "000000000000000100000", - "103439631": "000000000000000100000", - "104809461": "000000000000000100000", - "106149500": "000000000000000100000", - "108325795": "000000000000000100000", - "111139994": "000000000000000100000", - "112817979": "000000000000000100000", - "113613706": "000000000000000100000", - "113798117": "000000000000000100000", - "114163691": "000000000000000100000", - "115824651": "000000000000000100000", - "116370640": "000000000000000100000", - "116576545": "000000000000000100000", - "117142446": "000000000000000100000", - "118251425": "000000000000000100000", - "121594193": "000000000000000100000", - "122936037": "000000000000000100000", - "125116672": "000000000000000100000", - "126072399": "000000000000000100000", - "126993060": "000000000000000100000", - "127452478": "000000000000000100000", - "127643027": "000000000000000100000", - "127708148": "000000000000000100000", - "127825808": "000000000000000100000", - "128415031": "000000000000000100000", - "128417184": "000000000000000100000", - "128514282": "000000000000000100000", - "129863131": "000000000000000100000", - "130056138": "000000000000000100000", - "130267164": "000000000000000100000", - "130434906": "000000000000000100000", - "130756924": "000000000000000100000", - "130874777": "000000000000000100000", - "131386380": "000000000000000100000", - "131506391": "000000000000000100000", - "131945927": "000000000000000100000", - "133231548": "000000000000000100000", - "134130943": "000000000000000100000", - "134162985": "000000000000000100000", - "134391930": "000000000000000100000", - "134839427": "000000000000000100000", - "135266522": "000000000000000100000", - "135445468": "000000000000000100000", - "135759974": "000000000000000100000", - "136401284": "000000000000000100000", - "137453230": "000000000000000100000", - "138113654": "000000000000000100000", - "139049817": "000000000000000100000", - "139275092": "000000000000000100000", - "139439643": "000000000000000100000", - "140466107": "000000000000000100000", - "140675640": "000000000000000100000", - "142222598": "000000000000000100000", - "142283842": "000000000000000100000", - "145401758": "000000000000000100000", - "147271369": "000000000000000100000", - "147494960": "000000000000000100000", - "147756432": "000000000000000100000", - "148052055": "000000000000000100000", - "148689106": "000000000000000100000", - "149518908": "000000000000000100000", - "149682015": "000000000000000100000", - "152738862": "000000000000000100000", - "152865429": "000000000000000100000", - "154055773": "000000000000000100000", - "154056455": "000000000000000100000", - "155426847": "000000000000000100000", - "157245603": "000000000000000100000", - "160122662": "000000000000000100000", - "160142810": "000000000000000100000", - "160528653": "000000000000000100000", - "161943521": "000000000000000100000", - "162680368": "000000000000000100000", - "163021843": "000000000000000100000", - "164496385": "000000000000000100000", - "165833586": "000000000000000100000", - "165964523": "000000000000000100000", - "167421946": "000000000000000100000", - "169748439": "000000000000000100000", - "170340736": "000000000000000100000", - "170474276": "000000000000000100000", - "172175568": "000000000000000100000", - "172258756": "000000000000000100000", - "173808131": "000000000000000100000", - "173881902": "000000000000000100000", - "174035568": "000000000000000100000", - "174203367": "000000000000000100000", - "176507257": "000000000000000100000", - "176909570": "000000000000000100000", - "178427529": "000000000000000100000", - "179172560": "000000000000000100000", - "179339242": "000000000000000100000", - "179824250": "000000000000000100000", - "180222504": "000000000000000100000", - "181004480": "000000000000000100000", - "181295276": "000000000000000100000", - "182838852": "000000000000000100000", - "183572402": "000000000000000100000", - "184368287": "000000000000000100000", - "184761142": "000000000000000100000", - "185276773": "000000000000000100000", - "185282563": "000000000000000100000", - "187278014": "000000000000000100000", - "187790696": "000000000000000100000", - "188177947": "000000000000000100000", - "188681089": "000000000000000100000", - "189081104": "000000000000000100000", - "190162243": "000000000000000100000", - "190173528": "000000000000000100000", - "190550116": "000000000000000100000", - "190780095": "000000000000000100000", - "191014785": "000000000000000100000", - "191443734": "000000000000000100000", - "192772109": "000000000000000100000", - "196188473": "000000000000000100000", - "198249681": "000000000000000100000", - "198609613": "000000000000000100000", - "198619772": "000000000000000100000", - "198714600": "000000000000000100000", - "200255915": "000000000000000100000", - "200852517": "000000000000000100000", - "201107244": "000000000000000100000", - "201329605": "000000000000000100000", - "201413923": "000000000000000100000", - "201483496": "000000000000000100000", - "201757505": "000000000000000100000", - "201980373": "000000000000000100000", - "202083965": "000000000000000100000", - "203919267": "000000000000000100000", - "205518065": "000000000000000100000", - "206002467": "000000000000000100000", - "206854954": "000000000000000100000", - "206910078": "000000000000000100000", - "207397401": "000000000000000100000", - "207739004": "000000000000000100000", - "207765269": "000000000000000100000", - "209370800": "000000000000000100000", - "210627205": "000000000000000100000", - "211584279": "000000000000000100000", - "213233958": "000000000000000100000", - "213472736": "000000000000000100000", - "213960221": "000000000000000100000", - "214602579": "000000000000000100001", - "214915962": "000000000000000100000", - "215551650": "000000000000000100000", - "215935424": "000000000000000100000", - "216414385": "000000000000000100000", - "217295887": "000000000000000100000", - "217348069": "000000000000000100000", - "217499990": "000000000000000100000", - "217768480": "000000000000000100000", - "218226242": "000000000000000100000", - "218638413": "000000000000000100000", - "218653140": "000000000000000100000", - "219107512": "000000000000000100000", - "219532864": "000000000000000100000", - "220519590": "000000000000000100000", - "220826455": "000000000000000100000", - "221406281": "000000000000000100000", - "222631846": "000000000000000100000", - "222903662": "000000000000000100000", - "223725639": "000000000000000100000", - "224233253": "000000000000000100000", - "226412604": "000000000000000100000", - "226504145": "000000000000000100000", - "226818680": "000000000000000100000", - "226905247": "000000000000000100000", - "226930758": "000000000000000100000", - "227169668": "000000000000000100000", - "227430997": "000000000000000100000", - "227574085": "000000000000000100000", - "228274991": "000000000000000100000", - "230343991": "000000000000000100000", - "231416460": "000000000000000100000", - "232073691": "000000000000000100000", - "232591355": "000000000000000100000", - "233507550": "000000000000000100000", - "233917546": "000000000000000100000", - "234296850": "000000000000000100000", - "235296440": "000000000000000100000", - "235370710": "000000000000000100000", - "237549218": "000000000000000100000", - "237867753": "000000000000000110000", - "238305201": "000000000000000100000", - "238642890": "000000000000000100000", - "241669972": "000000000000000100000", - "242977489": "000000000000000100000", - "243185193": "000000000000000100000", - "246029469": "000000000000000100000", - "246562417": "000000000000000100000", - "247235211": "000000000000000100000", - "247966686": "000000000000000100000", - "248352431": "000000000000000100000", - "248660346": "000000000000000100000", - "249181787": "000000000000000100000", - "249702801": "000000000000000100000", - "250394445": "000000000000000100000", - "250736490": "000000000000000100000", - "252974050": "000000000000000100000", - "253069781": "000000000000000100000", - "256280747": "000000000000000100000", - "256696265": "000000000000000100000", - "256734751": "000000000000000100000", - "257531264": "000000000000000100000", - "258213634": "000000000000000100000", - "261335343": "000000000000000100000", - "261353314": "000000000000000100000", - "262251547": "000000000000000100000", - "264351848": "000000000000000100000", - "264818349": "000000000000000100000", - "264880241": "000000000000000100000", - "264955903": "000000000000000100000", - "265215888": "000000000000000100000", - "265322006": "000000000000000100000", - "266104963": "000000000000000100000", - "266136347": "000000000000000100000", - "266286590": "000000000000000100000", - "267280182": "000000000000000100000", - "267371448": "000000000000000100000", + "9847062": "000000000000000100110", + "18431190": "000000000000000100000", + "28776162": "000000000000000100000", + "30830812": "000000000000000100000", + "32867930": "000000000000000100000", + "38449435": "000000000000000100000", + "38454037": "000000000000000100000", + "52490238": "000000000000000100000", + "57537392": "000000000000000100000", + "64931916": "000000000000000100000", + "69027804": "000000000000000100000", + "74492946": "000000000000000100000", + "83838804": "000000000000000100000", + "85332092": "000000000000000100000", + "85350628": "000000000000000100000", + "88501328": "000000000000000100000", + "92208081": "000000000000000100000", + "92715394": "000000000000000100000", + "97559091": "000000000000000100000", + "100000447": "000000000000000100000", + "101071879": "000000000000000100000", + "118656040": "000000000000000100000", + "119372343": "000000000000000100000", + "119890824": "000000000000000100000", + "120916290": "000000000000000100000", + "127100158": "000000000000000100000", + "139395798": "000000000000000100000", + "144560810": "000000000000000100000", + "158436215": "000000000000000100000", + "169267934": "000000000000000100000", + "169631950": "000000000000000100000", + "176457756": "000000000000000100000", + "178685171": "000000000000000100000", + "179973687": "000000000000000100000", + "181176947": "000000000000000100000", + "202317146": "000000000000000100000", + "205170344": "000000000000000100000", + "218389449": "000000000000000100000", + "223258193": "000000000000000100000", + "238593185": "000000000000000100000", + "240529529": "000000000000000100110", + "245712397": "000000000000000100000", + "251224389": "000000000000000100000", + "253318345": "000000000000000100000", + "255045879": "000000000000000100000", "131351": "000000000000000010000", "159320": "000000000000000010000", "304316": "000000000000000010000", @@ -18133,6 +17761,7 @@ "237329254": "000000000000000010000", "237590676": "000000000000000010000", "237819913": "000000000000000011000", + "237867753": "000000000000000010000", "238662340": "000000000000000010000", "238741040": "000000000000000010000", "239076856": "000000000000000010000", @@ -18417,6 +18046,7 @@ "62277657": "000000000000000001000", "62586457": "000000000000000001000", "63675916": "000000000000000001000", + "63700259": "000000000000000001000", "64462250": "000000000000000001000", "64719076": "000000000000000001000", "64732222": "000000000000000001000", @@ -19465,6 +19095,7 @@ "78964817": "000000000000000000110", "79132906": "000000000000000000110", "79166135": "000000000000000000100", + "79218441": "000000000000000000110", "79637567": "000000000000000000110", "79705386": "000000000000000000110", "79738968": "000000000000000000100", @@ -20852,6 +20483,7 @@ "42629009": "000000000000000000001", "42825582": "000000000000000000001", "42997888": "000000000000000000001", + "43703499": "000000000000000000001", "43907703": "000000000000000000001", "44194370": "000000000000000000001", "44329058": "000000000000000000001", @@ -21257,6 +20889,7 @@ "214051426": "000000000000000000001", "214153212": "000000000000000000001", "214434029": "000000000000000000001", + "214602579": "000000000000000000001", "214892668": "000000000000000000001", "215834681": "000000000000000000001", "216735821": "000000000000000000001", @@ -21460,19 +21093,19 @@ "nMinimizers": 544 }, { - "name": "nextstrain/mpx/hmpxv-b1/pseudo_ON563414", + "name": "nextstrain/mpox/all-clades", "length": 197209, - "nMinimizers": 12020 + "nMinimizers": 12012 }, { - "name": "nextstrain/mpx/hmpxv/NC_063383.1", + "name": "nextstrain/mpox/clade-iib", "length": 197209, "nMinimizers": 12012 }, { - "name": "nextstrain/mpx/mpxv/ancestral", + "name": "nextstrain/mpox/lineage-b.1", "length": 197209, - "nMinimizers": 12043 + "nMinimizers": 12020 }, { "name": "nextstrain/rsv/a/EPI_ISL_412866", @@ -21514,9 +21147,9 @@ 15.566666666666666, 15.81081081081081, 16.876838235294116, - 16.406738768718803, 16.417665667665666, - 16.37540479946857, + 16.417665667665666, + 16.406738768718803, 15.59938524590164, 16.280213903743316, 16.172525689561926, diff --git a/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/CHANGELOG.md b/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/CHANGELOG.md new file mode 100644 index 00000000..a254d313 --- /dev/null +++ b/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/CHANGELOG.md @@ -0,0 +1,14 @@ +## Unreleased + +Initial release of this dataset. This dataset is similar to the v2 dataset [`MPXV/ancestral`](https://github.com/nextstrain/nextclade_data/tree/2023-08-17--15-51-24--UTC/data/datasets/MPXV/references/ancestral/versions/2023-08-01T12%3A00%3A00Z/files) with some differences. + +Read more about Nextclade datasets in the documentation: https://docs.nextstrain.org/projects/nextclade/en/stable/user/datasets.html + +### Important changes compared to v2 dataset + +- Some genes have been renamed and one has been added. The new annotation is based on NCBI refseq annotations that were released in November 2022. The v2 dataset predates this refseq. + - The 4 genes in the inverted terminal repeat segment (ITR) on both ends of the genome (OPG001, OPG002, OPG003,OPG015) are now all included. The genes on the 3' end (~positions 190000-197000) now have an `_dup` appended to distinguish them. + - The gene previously named `NBT03_gp052` is now called `OPG073` + - The gene previously named `NBT03_gp174` is now called `OPG016` + - The gene previously named `NBT03_gp175` is now called `OPG015_dup` + - Gene `OPG166` has been added diff --git a/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/README.md b/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/README.md new file mode 100644 index 00000000..67b2b3a5 --- /dev/null +++ b/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/README.md @@ -0,0 +1,27 @@ +# Nextclade dataset for "Mpox virus (All Clades)" + +| property | value | +| ------------------- | ------------------------------------------------------------------------------------------------------------------------------------------------------- | +| authors | [Cornelius Roemer](https://neherlab.org), [Richard Neher](https://neherlab.org), [Nextstrain](https://nextstrain.org) | +| data source | Genbank | +| workflow | [github.com/nextstrain/mpox/nextclade](https://github.com/nextstrain/mpox/nextclade) | +| issues | github.com/nextstrain/mpox/issues | +| nextclade data path | nextstrain/mpox/all-clades/rivers-with-ancestral-snps | +| title | Mpox virus (All Clades) | +| taxon | [NCBI:txid10244](https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=10244) | +| annotation | [NC_063383.1](https://www.ncbi.nlm.nih.gov/nuccore/NC_063383) | +| clade definitions | github.com/mpxv-lineages/lineage-designation | +| references | [Urgent need for a non-discriminatory and non-stigmatizing nomenclature for monkeypox virus](https://doi.org/10.1371/journal.pbio.3001769) | +| related datasets | Mpox virus (Clade IIb): `nextstrain/mpox/lineage-iib/rivers`
Mpox virus (Lineage B.1) `nextstrain/mpox/lineage-iib/rivers-with-usa-2022-ma001-snps` | + +This Nextclade dataset is intended for use with Mpox viruses of all clades (I, IIa and IIb). If your sequences are all from clade IIb, you may want to use the more specific dataset for that clade instead: `nextstrain/mpox/lineage-iib/rivers`. If your sequences are not only all from clade IIb but also specifically from the 2022 outbreak lineage B.1 (and sublineages), you may want to use the even more specific dataset for that lineage instead: `nextstrain/mpox/lineage-iib/rivers-with-usa-2022-ma001-snps`. The more specific a dataset, the faster it will run and the less overwhelming the results will be (fewer SNPs), more relevant reference sequences will be included for tree placement. + +The dataset supports calling broad Mpox virus clades (I, IIa, IIb) and for sequences within clade IIb the more focused lineages (A, A.1, A.2, A.3, A.1.1, B.1, etc.). The clade and lineage nomenclature used is outlined in [Urgent need for a non-discriminatory and non-stigmatizing nomenclature for monkeypox virus](https://doi.org/10.1371/journal.pbio.3001769). The ground truth for lineage definitions is available at [github.com/mpxv-lineages/lineage-designation](https://github.com/nextstrain/mpox/nextclade). This dataset will be updated as new lineages are designated. + +The reference used in this dataset is based on mpox virus NCBI refseq NC_063383.1 (`MPXV-M5312_HM12_Rivers`) but with SNPs (but not indels) that were inferred to be in the ancestor of clades I and II with a suitable orthopox outgroup. Due to this construction, the nucleotide and amino acid coordinates are hence identical to NC_063383.1. + +The sequences used for construction of the reference tree are obtained from the `/ingest` workflow of the `nextstrain/monkeypox` repo. This workflow downloads and processes sequences from NCBI/Genbank. Sequences are sampled from all clades and all lineages over time and countries for a representative sample of the diversity of Mpox virus. The sequences are then aligned with Nextclade and a maximum likelihood tree is inferred with IQ-TREE. The tree is then rooted with the reconstructed ancestral sequence and ancestral states are inferred with TreeTime. + +## Further reading + +Read more about Nextclade datasets in Nextclade documentation: https://docs.nextstrain.org/projects/nextclade/en/stable/user/datasets.html diff --git a/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/genome_annotation.gff3 b/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/genome_annotation.gff3 new file mode 100644 index 00000000..432d5465 --- /dev/null +++ b/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/genome_annotation.gff3 @@ -0,0 +1,391 @@ +##gff-version 3 +#!gff-spec-version 1.21 +#!processor NCBI annotwriter +##sequence-region NC_063383.1 1 197209 +##species https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10244 +NC_063383.1 RefSeq region 1 197209 . + . ID=NC_063383.1:1..197209;Dbxref=taxon:10244;collection-date=2018-08;country=Nigeria: Rivers State;gbkey=Src;genome=genomic;genotype=MPXV clade 2;isolate=MPXV-M5312_HM12_Rivers;mol_type=genomic DNA;nat-host=Homo sapiens +NC_063383.1 RefSeq long_terminal_repeat 1 6422 . - . ID=id-NC_063383.1:1..6422;gbkey=repeat_region;rpt_type=long_terminal_repeat +NC_063383.1 RefSeq gene 835 1575 . - . ID=gene-NBT03_gp001;Dbxref=GeneID:72551607;Name=OPG001;gbkey=Gene;gene=OPG001;gene_biotype=protein_coding;locus_tag=NBT03_gp001;old_locus_tag=MPXV-M5312_HM12_Rivers-001 +NC_063383.1 RefSeq CDS 835 1575 . - 0 ID=cds-YP_010377002.1;Parent=gene-NBT03_gp001;Dbxref=GenBank:YP_010377002.1,GeneID:72551607;Name=OPG001;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp001%3B Chemokine binding protein (Cop-C23L)%3B most abundant secreted protein%3B CC-chemokine binding%3B similar to VACV-WR J1L and VACV-Cop C23L;gbkey=CDS;gene=OPG001;locus_tag=NBT03_gp001;product=Chemokine binding protein;protein_id=YP_010377002.1 +NC_063383.1 RefSeq gene 1702 2751 . - . ID=gene-NBT03_gp002;Dbxref=GeneID:72551418;Name=OPG002;gbkey=Gene;gene=OPG002;gene_biotype=protein_coding;locus_tag=NBT03_gp002;old_locus_tag=MPXV-M5312_HM12_Rivers-002 +NC_063383.1 RefSeq CDS 1702 2751 . - 0 ID=cds-YP_010377003.1;Parent=gene-NBT03_gp002;Dbxref=GenBank:YP_010377003.1,GeneID:72551418;Name=OPG002;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: NBT03_gp002%3B TNF receptor (CrmB)%3B similar to VACV-WR J2L and VACV-Cop C22L;gbkey=CDS;gene=OPG002;locus_tag=NBT03_gp002;product=Crm-B secreted TNF-alpha-receptor-like protein;protein_id=YP_010377003.1 +NC_063383.1 RefSeq gene 2841 4607 . - . ID=gene-NBT03_gp003;Dbxref=GeneID:72551419;Name=OPG003;gbkey=Gene;gene=OPG003;gene_biotype=protein_coding;locus_tag=NBT03_gp003;old_locus_tag=MPXV-M5312_HM12_Rivers-003 +NC_063383.1 RefSeq CDS 2841 4607 . - 0 ID=cds-YP_010377004.1;Parent=gene-NBT03_gp003;Dbxref=GenBank:YP_010377004.1,GeneID:72551419;Name=OPG003;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp003%3B Ankyrin%3B similar to VACV-WR J3L and VACV-Cop C19L;gbkey=CDS;gene=OPG003;locus_tag=NBT03_gp003;product=Ankyrin repeat protein (25);protein_id=YP_010377004.1 +NC_063383.1 RefSeq gene 4843 6156 . - . ID=gene-NBT03_gp004;Dbxref=GeneID:72551420;Name=OPG015;gbkey=Gene;gene=OPG015;gene_biotype=protein_coding;locus_tag=NBT03_gp004;old_locus_tag=MPXV-M5312_HM12_Rivers-004 +NC_063383.1 RefSeq CDS 4843 6156 . - 0 ID=cds-YP_010377005.1;Parent=gene-NBT03_gp004;Dbxref=GenBank:YP_010377005.1,GeneID:72551420;Name=OPG015;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp004%3B Ankyrin%3B similar to VACV-WR D1L and CPXV-017;gbkey=CDS;gene=OPG015;locus_tag=NBT03_gp004;product=Ankyrin repeat protein (39);protein_id=YP_010377005.1 +NC_063383.1 RefSeq sequence_feature 6270 6419 . - . ID=id-NC_063383.1:6270..6419;exon_number=OPG016;gbkey=misc_feature;number=OPG016 +NC_063383.1 RefSeq sequence_feature 6444 6885 . - . ID=id-NC_063383.1:6444..6885;exon_number=OPG017;gbkey=misc_feature;number=OPG017 +NC_063383.1 RefSeq sequence_feature 6966 7463 . - . ID=id-NC_063383.1:6966..7463;exon_number=OPG018;gbkey=misc_feature;number=OPG018 +NC_063383.1 RefSeq gene 7580 8008 . + . ID=gene-NBT03_gp005;Dbxref=GeneID:72551421;Name=OPG019;gbkey=Gene;gene=OPG019;gene_biotype=protein_coding;locus_tag=NBT03_gp005;old_locus_tag=MPXV-M5312_HM12_Rivers-006 +NC_063383.1 RefSeq CDS 7580 8008 . + 0 ID=cds-YP_010377006.1;Parent=gene-NBT03_gp005;Dbxref=GenBank:YP_010377006.1,GeneID:72551421;Name=OPG019;Note=Taxonomic breadth: chordopoxvirinae%3B secreted growth factor Secreted EGF-like protein%3B similar to VACV-WR D3R and VACV-Cop C11R;gbkey=CDS;gene=OPG019;locus_tag=NBT03_gp005;product=EGF-like domain protein;protein_id=YP_010377006.1 +NC_063383.1 RefSeq sequence_feature 8136 9102 . - . ID=id-NC_063383.1:8136..9102;exon_number=OPG020;gbkey=misc_feature;number=OPG020 +NC_063383.1 RefSeq gene 9587 10315 . + . ID=gene-NBT03_gp006;Dbxref=GeneID:72551422;Name=OPG021;gbkey=Gene;gene=OPG021;gene_biotype=protein_coding;locus_tag=NBT03_gp006;old_locus_tag=MPXV-M5312_HM12_Rivers-008 +NC_063383.1 RefSeq CDS 9587 10315 . + 0 ID=cds-YP_010377007.1;Parent=gene-NBT03_gp006;Dbxref=GenBank:YP_010377007.1,GeneID:72551422;Name=OPG021;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp008%3B Zinc finger-like protein%3B zinc binding%3B virosome localization%3B virulence factor%3B inhibition of apoptosis induced by UV irradiation%3B similar to VACV-WR D5R;gbkey=CDS;gene=OPG021;locus_tag=NBT03_gp006;product=Zinc finger-like protein (2);protein_id=YP_010377007.1 +NC_063383.1 RefSeq gene 10478 10858 . - . ID=gene-NBT03_gp007;Dbxref=GeneID:72551423;Name=OPG022;gbkey=Gene;gene=OPG022;gene_biotype=protein_coding;locus_tag=NBT03_gp007;old_locus_tag=MPXV-M5312_HM12_Rivers-009 +NC_063383.1 RefSeq CDS 10478 10858 . - 0 ID=cds-YP_010377008.1;Parent=gene-NBT03_gp007;Dbxref=GenBank:YP_010377008.1,GeneID:72551423;Name=OPG022;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp009%3B secreted IL-18 binding protein%3B Soluble IL-18 binding protein (Bsh-D7L)%3B similar to VACV-WR D6L;gbkey=CDS;gene=OPG022;locus_tag=NBT03_gp007;product=Interleukin-18-binding protein;protein_id=YP_010377008.1 +NC_063383.1 RefSeq gene 10918 12900 . - . ID=gene-NBT03_gp008;Dbxref=GeneID:72551424;Name=OPG023;gbkey=Gene;gene=OPG023;gene_biotype=protein_coding;locus_tag=NBT03_gp008;old_locus_tag=MPXV-M5312_HM12_Rivers-010 +NC_063383.1 RefSeq CDS 10918 12900 . - 0 ID=cds-YP_010377009.1;Parent=gene-NBT03_gp008;Dbxref=GenBank:YP_010377009.1,GeneID:72551424;Name=OPG023;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp010%3B host range%3B ankyrin-like%3B Ankyrin/Host Range (Bang-D8L)%3B similar to VACV-WR D7L;gbkey=CDS;gene=OPG023;locus_tag=NBT03_gp008;product=Ankyrin repeat protein (2);protein_id=YP_010377009.1 +NC_063383.1 RefSeq gene 13034 13228 . - . ID=gene-NBT03_gp009;Dbxref=GeneID:72551425;Name=OPG024;gbkey=Gene;gene=OPG024;gene_biotype=protein_coding;locus_tag=NBT03_gp009;old_locus_tag=MPXV-M5312_HM12_Rivers-011 +NC_063383.1 RefSeq CDS 13034 13228 . - 0 ID=cds-YP_010377010.1;Parent=gene-NBT03_gp009;Dbxref=GenBank:YP_010377010.1,GeneID:72551425;Name=OPG024;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp011%3B ANK-containing protein%3B similar to VACV-WR D8L;gbkey=CDS;gene=OPG024;locus_tag=NBT03_gp009;product=retroviral pseudoprotease-like protein;protein_id=YP_010377010.1 +NC_063383.1 RefSeq gene 13375 15267 . - . ID=gene-NBT03_gp010;Dbxref=GeneID:72551426;Name=OPG025;gbkey=Gene;gene=OPG025;gene_biotype=protein_coding;locus_tag=NBT03_gp010;old_locus_tag=MPXV-M5312_HM12_Rivers-012 +NC_063383.1 RefSeq CDS 13375 15267 . - 0 ID=cds-YP_010377011.1;Parent=gene-NBT03_gp010;Dbxref=GenBank:YP_010377011.1,GeneID:72551426;Name=OPG025;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp012%3B ankyrin-like%3B Type I IFN resistance%3B similar to VACV-WR D9L and VACV-Cop C9L;gbkey=CDS;gene=OPG025;locus_tag=NBT03_gp010;product=Ankyrin repeat protein (14);protein_id=YP_010377011.1 +NC_063383.1 RefSeq sequence_feature 15310 15854 . - . ID=id-NC_063383.1:15310..15854;exon_number=OPG026;gbkey=misc_feature;number=OPG026 +NC_063383.1 RefSeq gene 15925 16377 . - . ID=gene-NBT03_gp011;Dbxref=GeneID:72551427;Name=OPG027;gbkey=Gene;gene=OPG027;gene_biotype=protein_coding;locus_tag=NBT03_gp011;old_locus_tag=MPXV-M5312_HM12_Rivers-013 +NC_063383.1 RefSeq CDS 15925 16377 . - 0 ID=cds-YP_010377012.1;Parent=gene-NBT03_gp011;Dbxref=GenBank:YP_010377012.1,GeneID:72551427;Name=OPG027;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp013%3B host range%3B Type 1 IFN inhibitor%3B similar to VACV-WR D10L and VACV-Cop C7L;gbkey=CDS;gene=OPG027;locus_tag=NBT03_gp011;product=Host range protein;protein_id=YP_010377012.1 +NC_063383.1 RefSeq gene 16602 17069 . - . ID=gene-NBT03_gp012;Dbxref=GeneID:72551428;Name=OPG029;gbkey=Gene;gene=OPG029;gene_biotype=protein_coding;locus_tag=NBT03_gp012;old_locus_tag=MPXV-M5312_HM12_Rivers-014 +NC_063383.1 RefSeq CDS 16602 17069 . - 0 ID=cds-YP_010377013.1;Parent=gene-NBT03_gp012;Dbxref=GenBank:YP_010377013.1,GeneID:72551428;Name=OPG029;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp014%3B Putative tlr signaling inhibitor%2C IFN-beta inhibitor%3B similar to VACV-WR D11L and VACV-Cop C6L;gbkey=CDS;gene=OPG029;locus_tag=NBT03_gp012;product=Bcl-2-like protein;protein_id=YP_010377013.1 +NC_063383.1 RefSeq gene 17213 17833 . - . ID=gene-NBT03_gp013;Dbxref=GeneID:72551429;Name=OPG030;gbkey=Gene;gene=OPG030;gene_biotype=protein_coding;locus_tag=NBT03_gp013;old_locus_tag=MPXV-M5312_HM12_Rivers-015 +NC_063383.1 RefSeq CDS 17213 17833 . - 0 ID=cds-YP_010377014.1;Parent=gene-NBT03_gp013;Dbxref=GenBank:YP_010377014.1,GeneID:72551429;Name=OPG030;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp015%3B BTB domain of kelch-like protein%3B Kelch-like protein%3B similar to VACV-WR D12L and VACV-Cop C5L;gbkey=CDS;gene=OPG030;locus_tag=NBT03_gp013;product=Kelch-like protein (1);protein_id=YP_010377014.1 +NC_063383.1 RefSeq gene 17878 18828 . - . ID=gene-NBT03_gp014;Dbxref=GeneID:72551430;Name=OPG031;gbkey=Gene;gene=OPG031;gene_biotype=protein_coding;locus_tag=NBT03_gp014;old_locus_tag=MPXV-M5312_HM12_Rivers-016 +NC_063383.1 RefSeq CDS 17878 18828 . - 0 ID=cds-YP_010377015.1;Parent=gene-NBT03_gp014;Dbxref=GenBank:YP_010377015.1,GeneID:72551430;Name=OPG031;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp016%3B IL-1 receptor antagonist%3B similar to VACV-WR D13L and VACV-Cop C10L;gbkey=CDS;gene=OPG031;locus_tag=NBT03_gp014;product=C4L/C10L-like family protein;protein_id=YP_010377015.1 +NC_063383.1 RefSeq sequence_feature 18902 19288 . - . ID=id-NC_063383.1:18902..19288;exon_number=OPG033;gbkey=misc_feature;number=OPG033 +NC_063383.1 RefSeq gene 19361 20005 . - . ID=gene-NBT03_gp015;Dbxref=GeneID:72551431;Name=OPG034;gbkey=Gene;gene=OPG034;gene_biotype=protein_coding;locus_tag=NBT03_gp015;old_locus_tag=MPXV-M5312_HM12_Rivers-018 +NC_063383.1 RefSeq CDS 19361 20005 . - 0 ID=cds-YP_010377017.1;Parent=gene-NBT03_gp015;Dbxref=GenBank:YP_010377017.1,GeneID:72551431;Name=OPG034;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp022%3B Putative TLR signalling inhibitor%3B start of ORF is missing approx. 18 AA compared to CPXVs%3B similar to VACV-WR D19L and VACV-Cop C1L;gbkey=CDS;gene=OPG034;locus_tag=NBT03_gp015;product=Bcl-2-like protein;protein_id=YP_010377017.1 +NC_063383.1 RefSeq gene 20051 20404 . - . ID=gene-NBT03_gp016;Dbxref=GeneID:72551432;Name=OPG035;gbkey=Gene;gene=OPG035;gene_biotype=protein_coding;locus_tag=NBT03_gp016;old_locus_tag=MPXV-M5312_HM12_Rivers-019 +NC_063383.1 RefSeq CDS 20051 20404 . - 0 ID=cds-YP_010377018.1;Parent=gene-NBT03_gp016;Dbxref=GenBank:YP_010377018.1,GeneID:72551432;Name=OPG035;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp023%3B secreted virulence factor%3B Putative tlr signaling inhibitor%3B Anti-apoptotic Bcl-2-like protein%3B similar to VACV-WR P1L and VACV-Cop N1L;gbkey=CDS;gene=OPG035;locus_tag=NBT03_gp016;product=Bcl-2-like protein;protein_id=YP_010377018.1 +NC_063383.1 RefSeq gene 20531 21064 . - . ID=gene-NBT03_gp017;Dbxref=GeneID:72551433;Name=OPG036;gbkey=Gene;gene=OPG036;gene_biotype=protein_coding;locus_tag=NBT03_gp017;old_locus_tag=MPXV-M5312_HM12_Rivers-020 +NC_063383.1 RefSeq CDS 20531 21064 . - 0 ID=cds-YP_010377019.1;Parent=gene-NBT03_gp017;Dbxref=GenBank:YP_010377019.1,GeneID:72551433;Name=OPG036;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp024%3B Alpha amanatin target protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR P2L and VACV-Cop #N2L;gbkey=CDS;gene=OPG036;locus_tag=NBT03_gp017;product=Bcl-2-like protein;protein_id=YP_010377019.1 +NC_063383.1 RefSeq gene 21105 22433 . - . ID=gene-NBT03_gp018;Dbxref=GeneID:72551434;Name=OPG037;gbkey=Gene;gene=OPG037;gene_biotype=protein_coding;locus_tag=NBT03_gp018;old_locus_tag=MPXV-M5312_HM12_Rivers-021 +NC_063383.1 RefSeq CDS 21105 22433 . - 0 ID=cds-YP_010377020.1;Parent=gene-NBT03_gp018;Dbxref=GenBank:YP_010377020.1,GeneID:72551434;Name=OPG037;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp025%3B ankyrin-like%3B ANK-containing protein%3B apoptosis inhibitor%3B start of ORF is missing approx. 31 AA compared to CPXVs%3B similar to VACV-WR O1L and VACV-Cop M1L;gbkey=CDS;gene=OPG037;locus_tag=NBT03_gp018;product=Ankyrin-like protein (1);protein_id=YP_010377020.1 +NC_063383.1 RefSeq gene 22497 23159 . - . ID=gene-NBT03_gp019;Dbxref=GeneID:72551435;Name=OPG038;gbkey=Gene;gene=OPG038;gene_biotype=protein_coding;locus_tag=NBT03_gp019;old_locus_tag=MPXV-M5312_HM12_Rivers-022 +NC_063383.1 RefSeq CDS 22497 23159 . - 0 ID=cds-YP_010377021.1;Parent=gene-NBT03_gp019;Dbxref=GenBank:YP_010377021.1,GeneID:72551435;Name=OPG038;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp026%3B NFkB inhibitor%3B similar to VACV-WR O2L and VACV-Cop M2L;gbkey=CDS;gene=OPG038;locus_tag=NBT03_gp019;product=NFkB inhibitor;protein_id=YP_010377021.1 +NC_063383.1 RefSeq gene 23264 24118 . - . ID=gene-NBT03_gp020;Dbxref=GeneID:72551436;Name=OPG039;gbkey=Gene;gene=OPG039;gene_biotype=protein_coding;locus_tag=NBT03_gp020;old_locus_tag=MPXV-M5312_HM12_Rivers-023 +NC_063383.1 RefSeq CDS 23264 24118 . - 0 ID=cds-YP_010377022.1;Parent=gene-NBT03_gp020;Dbxref=GenBank:YP_010377022.1,GeneID:72551436;Name=OPG039;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp027%3B host range%3B ankyrin-like%3B Ankyrin/NFkB inhibitor%3B similar to VACV-WR C1L and VACV-Cop K1L;gbkey=CDS;gene=OPG039;locus_tag=NBT03_gp020;product=Ankyrin-like protein (3);protein_id=YP_010377022.1 +NC_063383.1 RefSeq gene 24351 25478 . - . ID=gene-NBT03_gp021;Dbxref=GeneID:72551437;Name=OPG040;gbkey=Gene;gene=OPG040;gene_biotype=protein_coding;locus_tag=NBT03_gp021;old_locus_tag=MPXV-M5312_HM12_Rivers-024 +NC_063383.1 RefSeq CDS 24351 25478 . - 0 ID=cds-YP_010377023.1;Parent=gene-NBT03_gp021;Dbxref=GenBank:YP_010377023.1,GeneID:72551437;Name=OPG040;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp028%3B serine protease inhibitor-like%2C SPI-3%3B inhibition of the ability of infected cells to fuse%3B Serpin 1%2C2%2C3%3B similar to VACV-WR C2L and VACV-Cop K2L;gbkey=CDS;gene=OPG040;locus_tag=NBT03_gp021;product=Serpin;protein_id=YP_010377023.1 +NC_063383.1 RefSeq sequence_feature 25529 25767 . - . ID=id-NC_063383.1:25529..25767;exon_number=OPG041;gbkey=misc_feature;number=OPG041 +NC_063383.1 RefSeq gene 25823 27097 . - . ID=gene-NBT03_gp022;Dbxref=GeneID:72551438;Name=OPG042;gbkey=Gene;gene=OPG042;gene_biotype=protein_coding;locus_tag=NBT03_gp022;old_locus_tag=MPXV-M5312_HM12_Rivers-026 +NC_063383.1 RefSeq CDS 25823 27097 . - 0 ID=cds-YP_010377025.1;Parent=gene-NBT03_gp022;Dbxref=GenBank:YP_010377025.1,GeneID:72551438;Name=OPG042;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp030%3B phospholipase D-like%3B Phospholipase-D-like protein%3B similar to VACV-WR C4L and VACV-Cop K4L;gbkey=CDS;gene=OPG042;locus_tag=NBT03_gp022;product=Phospholipase-D-like protein;protein_id=YP_010377025.1 +NC_063383.1 RefSeq gene 27125 27955 . - . ID=gene-NBT03_gp023;Dbxref=GeneID:72551439;Name=OPG043;gbkey=Gene;gene=OPG043;gene_biotype=protein_coding;locus_tag=NBT03_gp023;old_locus_tag=MPXV-M5312_HM12_Rivers-027 +NC_063383.1 RefSeq CDS 27125 27955 . - 0 ID=cds-YP_010377026.1;Parent=gene-NBT03_gp023;Dbxref=GenBank:YP_010377026.1,GeneID:72551439;Name=OPG043;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp031%3B lysophospholipase-like%3B Monoglyceride lipase%3B similar to VACV-WR C5L and VACV-Cop K5L;gbkey=CDS;gene=OPG043;locus_tag=NBT03_gp023;product=Putative monoglyceride lipase;protein_id=YP_010377026.1 +NC_063383.1 RefSeq gene 28091 28540 . + . ID=gene-NBT03_gp024;Dbxref=GeneID:72551440;Name=OPG044;gbkey=Gene;gene=OPG044;gene_biotype=protein_coding;locus_tag=NBT03_gp024;old_locus_tag=MPXV-M5312_HM12_Rivers-028 +NC_063383.1 RefSeq CDS 28091 28540 . + 0 ID=cds-YP_010377027.1;Parent=gene-NBT03_gp024;Dbxref=GenBank:YP_010377027.1,GeneID:72551440;Name=OPG044;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp032%3B Putative tlr signaling inhibitor%3B Host immune response repressor%3B similar to VACV-WR C6R and VACV-Cop #K7R;gbkey=CDS;gene=OPG044;locus_tag=NBT03_gp024;product=Bcl-2-like protein;protein_id=YP_010377027.1 +NC_063383.1 RefSeq gene 28603 29262 . - . ID=gene-NBT03_gp025;Dbxref=GeneID:72551441;Name=OPG045;gbkey=Gene;gene=OPG045;gene_biotype=protein_coding;locus_tag=NBT03_gp025;old_locus_tag=MPXV-M5312_HM12_Rivers-029 +NC_063383.1 RefSeq CDS 28603 29262 . - 0 ID=cds-YP_010377028.1;Parent=gene-NBT03_gp025;Dbxref=GenBank:YP_010377028.1,GeneID:72551441;Name=OPG045;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp033%3B Caspase-9 (apoptosis) inhibitor (mitochondrial- associated)%3B similar to VACV-WR C7L and VACV-Cop F1L;gbkey=CDS;gene=OPG045;locus_tag=NBT03_gp025;product=Caspase-9 inhibitor;protein_id=YP_010377028.1 +NC_063383.1 RefSeq gene 29274 29729 . - . ID=gene-NBT03_gp026;Dbxref=GeneID:72551442;Name=OPG046;gbkey=Gene;gene=OPG046;gene_biotype=protein_coding;locus_tag=NBT03_gp026;old_locus_tag=MPXV-M5312_HM12_Rivers-030 +NC_063383.1 RefSeq CDS 29274 29729 . - 0 ID=cds-YP_010377029.1;Parent=gene-NBT03_gp026;Dbxref=GenBank:YP_010377029.1,GeneID:72551442;Name=OPG046;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp034%3B deoxyuridine triphosphatase%3B dUTPase%3B similar to VACV-WR C8L and VACV-Cop F2L;gbkey=CDS;gene=OPG046;locus_tag=NBT03_gp026;product=dUTPase;protein_id=YP_010377029.1 +NC_063383.1 RefSeq gene 29746 31194 . - . ID=gene-NBT03_gp027;Dbxref=GeneID:72551443;Name=OPG047;gbkey=Gene;gene=OPG047;gene_biotype=protein_coding;locus_tag=NBT03_gp027;old_locus_tag=MPXV-M5312_HM12_Rivers-031 +NC_063383.1 RefSeq CDS 29746 31194 . - 0 ID=cds-YP_010377030.1;Parent=gene-NBT03_gp027;Dbxref=GenBank:YP_010377030.1,GeneID:72551443;Name=OPG047;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp035%3B kelch-like%3B Kelch-like protein%3B similar to VACV-WR C9L and VACV-Cop F3L;gbkey=CDS;gene=OPG047;locus_tag=NBT03_gp027;product=Kelch-like protein (2);protein_id=YP_010377030.1 +NC_063383.1 RefSeq gene 31205 32164 . - . ID=gene-NBT03_gp028;Dbxref=GeneID:72551444;Name=OPG048;gbkey=Gene;gene=OPG048;gene_biotype=protein_coding;locus_tag=NBT03_gp028;old_locus_tag=MPXV-M5312_HM12_Rivers-032 +NC_063383.1 RefSeq CDS 31205 32164 . - 0 ID=cds-YP_010377031.1;Parent=gene-NBT03_gp028;Dbxref=GenBank:YP_010377031.1,GeneID:72551444;Name=OPG048;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp036%3B Ribonucleotide reductase small subunit%2C R2%3B similar to VACV-WR C10L and VACV-Cop F4L;gbkey=CDS;gene=OPG048;locus_tag=NBT03_gp028;product=Ribonucleotide reductase small subunit;protein_id=YP_010377031.1 +NC_063383.1 RefSeq gene 32195 33151 . - . ID=gene-NBT03_gp029;Dbxref=GeneID:72551445;Name=OPG049;gbkey=Gene;gene=OPG049;gene_biotype=protein_coding;locus_tag=NBT03_gp029;old_locus_tag=MPXV-M5312_HM12_Rivers-033 +NC_063383.1 RefSeq CDS 32195 33151 . - 0 ID=cds-YP_010377032.1;Parent=gene-NBT03_gp029;Dbxref=GenBank:YP_010377032.1,GeneID:72551445;Name=OPG049;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp037%3B 36kDa major membrane protein%3B similar to VACV-WR C11L and VACV-Cop F5L;gbkey=CDS;gene=OPG049;locus_tag=NBT03_gp029;product=Telomere-binding protein I6 (1);protein_id=YP_010377032.1 +NC_063383.1 RefSeq gene 33181 33408 . - . ID=gene-NBT03_gp030;Dbxref=GeneID:72551446;Name=OPG050;gbkey=Gene;gene=OPG050;gene_biotype=protein_coding;locus_tag=NBT03_gp030;old_locus_tag=MPXV-M5312_HM12_Rivers-034 +NC_063383.1 RefSeq CDS 33181 33408 . - 0 ID=cds-YP_010377033.1;Parent=gene-NBT03_gp030;Dbxref=GenBank:YP_010377033.1,GeneID:72551446;Name=OPG050;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp038%3B Hypothetical protein%3B similar to VACV-WR C12L and VACV-Cop F6L;gbkey=CDS;gene=OPG050;locus_tag=NBT03_gp030;product=CPXV053 protein;protein_id=YP_010377033.1 +NC_063383.1 RefSeq gene 33425 33649 . - . ID=gene-NBT03_gp031;Dbxref=GeneID:72551447;Name=OPG051;gbkey=Gene;gene=OPG051;gene_biotype=protein_coding;locus_tag=NBT03_gp031;old_locus_tag=MPXV-M5312_HM12_Rivers-035 +NC_063383.1 RefSeq CDS 33425 33649 . - 0 ID=cds-YP_010377034.1;Parent=gene-NBT03_gp031;Dbxref=GenBank:YP_010377034.1,GeneID:72551447;Name=OPG051;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp039%3B Hypothetical protein%3B similar to VACV-WR C13L and VACV-Cop F7L;gbkey=CDS;gene=OPG051;locus_tag=NBT03_gp031;product=CPXV054 protein;protein_id=YP_010377034.1 +NC_063383.1 RefSeq gene 33801 33995 . - . ID=gene-NBT03_gp032;Dbxref=GeneID:72551448;Name=OPG052;gbkey=Gene;gene=OPG052;gene_biotype=protein_coding;locus_tag=NBT03_gp032;old_locus_tag=MPXV-M5312_HM12_Rivers-036 +NC_063383.1 RefSeq CDS 33801 33995 . - 0 ID=cds-YP_010377035.1;Parent=gene-NBT03_gp032;Dbxref=GenBank:YP_010377035.1,GeneID:72551448;Name=OPG052;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp040%3B Cytoplasmic protein%3B similar to VACV-WR C14L and VACV-Cop F8L;gbkey=CDS;gene=OPG052;locus_tag=NBT03_gp032;product=Cytoplasmic protein;protein_id=YP_010377035.1 +NC_063383.1 RefSeq gene 34052 34690 . - . ID=gene-NBT03_gp033;Dbxref=GeneID:72551449;Name=OPG053;gbkey=Gene;gene=OPG053;gene_biotype=protein_coding;locus_tag=NBT03_gp033;old_locus_tag=MPXV-M5312_HM12_Rivers-037 +NC_063383.1 RefSeq CDS 34052 34690 . - 0 ID=cds-YP_010377036.1;Parent=gene-NBT03_gp033;Dbxref=GenBank:YP_010377036.1,GeneID:72551449;Name=OPG053;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp041%3B S-S bond formation pathway protein substrate%3B similar to VACV-WR C15L and VACV-Cop F9L;gbkey=CDS;gene=OPG053;locus_tag=NBT03_gp033;product=IMV membrane protein L1R;protein_id=YP_010377036.1 +NC_063383.1 RefSeq gene 34677 35996 . - . ID=gene-NBT03_gp034;Dbxref=GeneID:72551450;Name=OPG054;gbkey=Gene;gene=OPG054;gene_biotype=protein_coding;locus_tag=NBT03_gp034;old_locus_tag=MPXV-M5312_HM12_Rivers-038 +NC_063383.1 RefSeq CDS 34677 35996 . - 0 ID=cds-YP_010377037.1;Parent=gene-NBT03_gp034;Dbxref=GenBank:YP_010377037.1,GeneID:72551450;Name=OPG054;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp042%3B serine%3B Essential Ser/Thr kinase morph%3B similar to VACV-WR C16L and VACV-Cop F10L;gbkey=CDS;gene=OPG054;locus_tag=NBT03_gp034;product=Serine/threonine-protein kinase;protein_id=YP_010377037.1 +NC_063383.1 RefSeq gene 36019 37083 . - . ID=gene-NBT03_gp035;Dbxref=GeneID:72551451;Name=OPG055;gbkey=Gene;gene=OPG055;gene_biotype=protein_coding;locus_tag=NBT03_gp035;old_locus_tag=MPXV-M5312_HM12_Rivers-039 +NC_063383.1 RefSeq CDS 36019 37083 . - 0 ID=cds-YP_010377038.1;Parent=gene-NBT03_gp035;Dbxref=GenBank:YP_010377038.1,GeneID:72551451;Name=OPG055;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp043%3B RhoA signalling inhibitor%2C virus release protein%3B MC018%3B similar to VACV-WR C17L and VACV-Cop F11L;gbkey=CDS;gene=OPG055;locus_tag=NBT03_gp035;product=Protein F11;protein_id=YP_010377038.1 +NC_063383.1 RefSeq gene 37127 39034 . - . ID=gene-NBT03_gp036;Dbxref=GeneID:72551452;Name=OPG056;gbkey=Gene;gene=OPG056;gene_biotype=protein_coding;locus_tag=NBT03_gp036;old_locus_tag=MPXV-M5312_HM12_Rivers-040 +NC_063383.1 RefSeq CDS 37127 39034 . - 0 ID=cds-YP_010377039.1;Parent=gene-NBT03_gp036;Dbxref=GenBank:YP_010377039.1,GeneID:72551452;Name=OPG056;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp044%3B actin tail formation%3B EEV maturation protein%3B similar to VACV-WR C18L and VACV-Cop F12L;gbkey=CDS;gene=OPG056;locus_tag=NBT03_gp036;product=EEV maturation protein;protein_id=YP_010377039.1 +NC_063383.1 RefSeq gene 39077 40195 . - . ID=gene-NBT03_gp037;Dbxref=GeneID:72551453;Name=OPG057;gbkey=Gene;gene=OPG057;gene_biotype=protein_coding;locus_tag=NBT03_gp037;old_locus_tag=MPXV-M5312_HM12_Rivers-041 +NC_063383.1 RefSeq CDS 39077 40195 . - 0 ID=cds-YP_010377040.1;Parent=gene-NBT03_gp037;Dbxref=GenBank:YP_010377040.1,GeneID:72551453;Name=OPG057;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp045%3B major envelope antigen of EEV%3B wrapping of IMV to form IEV%3B phospholipase D-like%3B Palmitylated EEV membrane glycoprotein%3B similar to VACV-WR C19L and VACV-Cop F13L;gbkey=CDS;gene=OPG057;locus_tag=NBT03_gp037;product=Palmytilated EEV membrane protein;protein_id=YP_010377040.1 +NC_063383.1 RefSeq gene 40213 40434 . - . ID=gene-NBT03_gp038;Dbxref=GeneID:72551454;Name=OPG058;gbkey=Gene;gene=OPG058;gene_biotype=protein_coding;locus_tag=NBT03_gp038;old_locus_tag=MPXV-M5312_HM12_Rivers-042 +NC_063383.1 RefSeq CDS 40213 40434 . - 0 ID=cds-YP_010377041.1;Parent=gene-NBT03_gp038;Dbxref=GenBank:YP_010377041.1,GeneID:72551454;Name=OPG058;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp046%3B similar to VACV-WR C20L and VACV-Cop F14L;gbkey=CDS;gene=OPG058;locus_tag=NBT03_gp038;product=Protein F14 (1);protein_id=YP_010377041.1 +NC_063383.1 RefSeq gene 40484 40633 . - . ID=gene-NBT03_gp039;Dbxref=GeneID:72551455;Name=OPG059;gbkey=Gene;gene=OPG059;gene_biotype=protein_coding;locus_tag=NBT03_gp039;old_locus_tag=MPXV-M5312_HM12_Rivers-043 +NC_063383.1 RefSeq CDS 40484 40633 . - 0 ID=cds-YP_010377042.1;Parent=gene-NBT03_gp039;Dbxref=GenBank:YP_010377042.1,GeneID:72551455;Name=OPG059;Note=Taxonomic breadth: poxvirinae%3B IMV protein%3B C20.5L%3B similar to VACV-CopF14.5L;gbkey=CDS;gene=OPG059;locus_tag=NBT03_gp039;product=Cytochrome C oxidase;protein_id=YP_010377042.1 +NC_063383.1 RefSeq gene 40706 41182 . - . ID=gene-NBT03_gp040;Dbxref=GeneID:72551456;Name=OPG060;gbkey=Gene;gene=OPG060;gene_biotype=protein_coding;locus_tag=NBT03_gp040;old_locus_tag=MPXV-M5312_HM12_Rivers-044 +NC_063383.1 RefSeq CDS 40706 41182 . - 0 ID=cds-YP_010377043.1;Parent=gene-NBT03_gp040;Dbxref=GenBank:YP_010377043.1,GeneID:72551456;Name=OPG060;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp047%3B Unknown conserved protein%3B similar to VACV-WR C21L and VACV-Cop F15L;gbkey=CDS;gene=OPG060;locus_tag=NBT03_gp040;product=Protein F15;protein_id=YP_010377043.1 +NC_063383.1 RefSeq gene 41189 41884 . - . ID=gene-NBT03_gp041;Dbxref=GeneID:72551457;Name=OPG061;gbkey=Gene;gene=OPG061;gene_biotype=protein_coding;locus_tag=NBT03_gp041;old_locus_tag=MPXV-M5312_HM12_Rivers-045 +NC_063383.1 RefSeq CDS 41189 41884 . - 0 ID=cds-YP_010377044.1;Parent=gene-NBT03_gp041;Dbxref=GenBank:YP_010377044.1,GeneID:72551457;Name=OPG061;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp048%3B Non-functional Serine Recombinase%3B similar to VACV-WR C22L and VACV-Cop F16L;gbkey=CDS;gene=OPG061;locus_tag=NBT03_gp041;product=Protein F16 (1);protein_id=YP_010377044.1 +NC_063383.1 RefSeq gene 41947 42252 . + . ID=gene-NBT03_gp042;Dbxref=GeneID:72551458;Name=OPG062;gbkey=Gene;gene=OPG062;gene_biotype=protein_coding;locus_tag=NBT03_gp042;old_locus_tag=MPXV-M5312_HM12_Rivers-046 +NC_063383.1 RefSeq CDS 41947 42252 . + 0 ID=cds-YP_010377045.1;Parent=gene-NBT03_gp042;Dbxref=GenBank:YP_010377045.1,GeneID:72551458;Name=OPG062;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp049%3B virion core DNA-binding phosphoprotein (VP11)%3B mTOR antagonist%3B similar to VACV-WR C23R and VACV-Cop F17R;gbkey=CDS;gene=OPG062;locus_tag=NBT03_gp042;product=DNA-binding phosphoprotein (1);protein_id=YP_010377045.1 +NC_063383.1 RefSeq gene 42249 43688 . - . ID=gene-NBT03_gp043;Dbxref=GeneID:72551459;Name=OPG063;gbkey=Gene;gene=OPG063;gene_biotype=protein_coding;locus_tag=NBT03_gp043;old_locus_tag=MPXV-M5312_HM12_Rivers-047 +NC_063383.1 RefSeq CDS 42249 43688 . - 0 ID=cds-YP_010377046.1;Parent=gene-NBT03_gp043;Dbxref=GenBank:YP_010377046.1,GeneID:72551459;Name=OPG063;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp050%3B poly-A polymerase%2C Poly (A) polymerase catalytic subunit (VP55)%3B similar to VACV-WR F1L and VACV-Cop E1L;gbkey=CDS;gene=OPG063;locus_tag=NBT03_gp043;product=Poly(A) polymerase catalytic subunit (3);protein_id=YP_010377046.1 +NC_063383.1 RefSeq gene 43685 45898 . - . ID=gene-NBT03_gp044;Dbxref=GeneID:72551460;Name=OPG064;gbkey=Gene;gene=OPG064;gene_biotype=protein_coding;locus_tag=NBT03_gp044;old_locus_tag=MPXV-M5312_HM12_Rivers-048 +NC_063383.1 RefSeq CDS 43685 45898 . - 0 ID=cds-YP_010377047.1;Parent=gene-NBT03_gp044;Dbxref=GenBank:YP_010377047.1,GeneID:72551460;Name=OPG064;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp051%3B IEV morphogenesis%3B similar to VACV-WR F2L and VACV-Cop E2L;gbkey=CDS;gene=OPG064;locus_tag=NBT03_gp044;product=Iev morphogenesis protein;protein_id=YP_010377047.1 +NC_063383.1 RefSeq gene 46022 46483 . - . ID=gene-NBT03_gp045;Dbxref=GeneID:72551461;Name=OPG065;gbkey=Gene;gene=OPG065;gene_biotype=protein_coding;locus_tag=NBT03_gp045;old_locus_tag=MPXV-M5312_HM12_Rivers-049 +NC_063383.1 RefSeq CDS 46022 46483 . - 0 ID=cds-YP_010377048.1;Parent=gene-NBT03_gp045;Dbxref=GenBank:YP_010377048.1,GeneID:72551461;Name=OPG065;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp052%3B interferon resistance factor%3B two forms (25 kDa and 19 kDa) of the dsRNA-binding protein%3B inhibition of dsRNA-dependent protein kinase and 2-5A-synthet%3B dsRNA-binding protein%2C IFN resistance/PKR inhibitor (Z-DNA binding)%3B start of ORF is missing approx. 37 AA compared to CPXVs%3B similar to VACV-WR F3L and VACV-Cop E3L;gbkey=CDS;gene=OPG065;locus_tag=NBT03_gp045;product=Double-stranded RNA binding protein;protein_id=YP_010377048.1 +NC_063383.1 RefSeq gene 46649 47428 . - . ID=gene-NBT03_gp046;Dbxref=GeneID:72551462;Name=OPG066;gbkey=Gene;gene=OPG066;gene_biotype=protein_coding;locus_tag=NBT03_gp046;old_locus_tag=MPXV-M5312_HM12_Rivers-050 +NC_063383.1 RefSeq CDS 46649 47428 . - 0 ID=cds-YP_010377049.1;Parent=gene-NBT03_gp046;Dbxref=GenBank:YP_010377049.1,GeneID:72551462;Name=OPG066;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp053%3B RNA polymerase 30 kDa subunit (RPO30)%3B simultaneously intermediate stage promoter-specific transcription factor%2C VITF-1%3B similar to VACV-WR F4L and VACV-Cop E4L;gbkey=CDS;gene=OPG066;locus_tag=NBT03_gp046;product=DNA-directed RNA polymerase 30 kDa polypeptide;protein_id=YP_010377049.1 +NC_063383.1 RefSeq sequence_feature 47525 48062 . + . ID=id-NC_063383.1:47525..48062;exon_number=OPG067;gbkey=misc_feature;number=OPG067 +NC_063383.1 RefSeq gene 48201 49904 . + . ID=gene-NBT03_gp047;Dbxref=GeneID:72551463;Name=OPG068;gbkey=Gene;gene=OPG068;gene_biotype=protein_coding;locus_tag=NBT03_gp047;old_locus_tag=MPXV-M5312_HM12_Rivers-052 +NC_063383.1 RefSeq CDS 48201 49904 . + 0 ID=cds-YP_010377051.1;Parent=gene-NBT03_gp047;Dbxref=GenBank:YP_010377051.1,GeneID:72551463;Name=OPG068;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp054%3B Virion protein%3B similar to VACV-WR F5R and VACV-Cop E6R;gbkey=CDS;gene=OPG068;locus_tag=NBT03_gp047;product=IMV membrane protein E6;protein_id=YP_010377051.1 +NC_063383.1 RefSeq gene 49986 50486 . + . ID=gene-NBT03_gp048;Dbxref=GeneID:72551464;Name=OPG069;gbkey=Gene;gene=OPG069;gene_biotype=protein_coding;locus_tag=NBT03_gp048;old_locus_tag=MPXV-M5312_HM12_Rivers-053 +NC_063383.1 RefSeq CDS 49986 50486 . + 0 ID=cds-YP_010377052.1;Parent=gene-NBT03_gp048;Dbxref=GenBank:YP_010377052.1,GeneID:72551464;Name=OPG069;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp055%3B soluble myristylated protein%3B similar to VACV-WR F6R and VACV-Cop E7R;gbkey=CDS;gene=OPG069;locus_tag=NBT03_gp048;product=Myristoylated protein E7;protein_id=YP_010377052.1 +NC_063383.1 RefSeq gene 50590 51411 . + . ID=gene-NBT03_gp049;Dbxref=GeneID:72551465;Name=OPG070;gbkey=Gene;gene=OPG070;gene_biotype=protein_coding;locus_tag=NBT03_gp049;old_locus_tag=MPXV-M5312_HM12_Rivers-054 +NC_063383.1 RefSeq CDS 50590 51411 . + 0 ID=cds-YP_010377053.1;Parent=gene-NBT03_gp049;Dbxref=GenBank:YP_010377053.1,GeneID:72551465;Name=OPG070;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp056%3B ER-localized membrane protein%2C virion core protein%3B similar to VACV-WR F7R and VACV-Cop E8R;gbkey=CDS;gene=OPG070;locus_tag=NBT03_gp049;product=Membrane protein E8;protein_id=YP_010377053.1 +NC_063383.1 RefSeq gene 51418 54438 . - . ID=gene-NBT03_gp050;Dbxref=GeneID:72551466;Name=OPG071;gbkey=Gene;gene=OPG071;gene_biotype=protein_coding;locus_tag=NBT03_gp050;old_locus_tag=MPXV-M5312_HM12_Rivers-055 +NC_063383.1 RefSeq CDS 51418 54438 . - 0 ID=cds-YP_010377054.1;Parent=gene-NBT03_gp050;Dbxref=GenBank:YP_010377054.1,GeneID:72551466;Name=OPG071;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp057%3B DNA polymerase%2C catalytic subunit%3B similar to VACV-WR F8L and VACV-Cop E9L;gbkey=CDS;gene=OPG071;locus_tag=NBT03_gp050;product=DNA polymerase (2);protein_id=YP_010377054.1 +NC_063383.1 RefSeq gene 54470 54757 . + . ID=gene-NBT03_gp051;Dbxref=GeneID:72551467;Name=OPG072;gbkey=Gene;gene=OPG072;gene_biotype=protein_coding;locus_tag=NBT03_gp051;old_locus_tag=MPXV-M5312_HM12_Rivers-056 +NC_063383.1 RefSeq CDS 54470 54757 . + 0 ID=cds-YP_010377055.1;Parent=gene-NBT03_gp051;Dbxref=GenBank:YP_010377055.1,GeneID:72551467;Name=OPG072;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp058%3B protein disulfide bond-forming enzyme%3B Sulfhydryl oxidase (FAD-linked)%3B similar to VACV-WR F9R and VACV-Cop E10R;gbkey=CDS;gene=OPG072;locus_tag=NBT03_gp051;product=Sulfhydryl oxidase;protein_id=YP_010377055.1 +NC_063383.1 RefSeq gene 54752 55141 . - . ID=gene-NBT03_gp052;Dbxref=GeneID:72551468;Name=OPG073;gbkey=Gene;gene=OPG073;gene_biotype=protein_coding;locus_tag=NBT03_gp052;old_locus_tag=MPXV-M5312_HM12_Rivers-057 +NC_063383.1 RefSeq CDS 54752 55141 . - 0 ID=cds-YP_010377056.1;Parent=gene-NBT03_gp052;Dbxref=GenBank:YP_010377056.1,GeneID:72551468;Name=OPG073;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp059%3B virion core protein%3B similar to VACV-WR F10L and VACV-Cop E11L;gbkey=CDS;gene=OPG073;locus_tag=NBT03_gp052;product=Virion core protein E11;protein_id=YP_010377056.1 +NC_063383.1 RefSeq gene 55128 57125 . - . ID=gene-NBT03_gp053;Dbxref=GeneID:72551469;Name=OPG074;gbkey=Gene;gene=OPG074;gene_biotype=protein_coding;locus_tag=NBT03_gp053;old_locus_tag=MPXV-M5312_HM12_Rivers-058 +NC_063383.1 RefSeq CDS 55128 57125 . - 0 ID=cds-YP_010377057.1;Parent=gene-NBT03_gp053;Dbxref=GenBank:YP_010377057.1,GeneID:72551469;Name=OPG074;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp060%3B Membrane protein%3B similar to VACV-WR Q1L and VACV-Cop O1L;gbkey=CDS;gene=OPG074;locus_tag=NBT03_gp053;product=Iev morphogenesis protein;protein_id=YP_010377057.1 +NC_063383.1 RefSeq gene 57172 57498 . - . ID=gene-NBT03_gp054;Dbxref=GeneID:72551470;Name=OPG075;gbkey=Gene;gene=OPG075;gene_biotype=protein_coding;locus_tag=NBT03_gp054;old_locus_tag=MPXV-M5312_HM12_Rivers-059 +NC_063383.1 RefSeq CDS 57172 57498 . - 0 ID=cds-YP_010377058.1;Parent=gene-NBT03_gp054;Dbxref=GenBank:YP_010377058.1,GeneID:72551470;Name=OPG075;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp061%3B virion-associated glutaredoxin%3B glutaredoxin 1%3B similar to VACV-WR Q2L and VACV-Cop O2L;gbkey=CDS;gene=OPG075;locus_tag=NBT03_gp054;product=Glutaredoxin-1;protein_id=YP_010377058.1 +NC_063383.1 RefSeq gene 57523 57630 . - . ID=gene-NBT03_gp055;Dbxref=GeneID:72551471;Name=OPG076;gbkey=Gene;gene=OPG076;gene_biotype=protein_coding;locus_tag=NBT03_gp055 +NC_063383.1 RefSeq CDS 57523 57630 . - 0 ID=cds-YP_010377183.1;Parent=gene-NBT03_gp055;Dbxref=GenBank:YP_010377183.1,GeneID:72551471;Name=OPG076;gbkey=CDS;gene=OPG076;locus_tag=NBT03_gp055;product=MV membrane EFC component;protein_id=YP_010377183.1 +NC_063383.1 RefSeq gene 57645 58583 . - . ID=gene-NBT03_gp056;Dbxref=GeneID:72551472;Name=OPG077;gbkey=Gene;gene=OPG077;gene_biotype=protein_coding;locus_tag=NBT03_gp056;old_locus_tag=MPXV-M5312_HM12_Rivers-060 +NC_063383.1 RefSeq CDS 57645 58583 . - 0 ID=cds-YP_010377059.1;Parent=gene-NBT03_gp056;Dbxref=GenBank:YP_010377059.1,GeneID:72551472;Name=OPG077;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp062%3B virosomal protein essential for virus multiplication%3B DNA-binding core protein%3B similar to VACV-WR I1L and VACV-Cop I1L;gbkey=CDS;gene=OPG077;locus_tag=NBT03_gp056;product=Telomere-binding protein I1;protein_id=YP_010377059.1 +NC_063383.1 RefSeq gene 58590 58811 . - . ID=gene-NBT03_gp057;Dbxref=GeneID:72551473;Name=OPG078;gbkey=Gene;gene=OPG078;gene_biotype=protein_coding;locus_tag=NBT03_gp057;old_locus_tag=MPXV-M5312_HM12_Rivers-061 +NC_063383.1 RefSeq CDS 58590 58811 . - 0 ID=cds-YP_010377060.1;Parent=gene-NBT03_gp057;Dbxref=GenBank:YP_010377060.1,GeneID:72551473;Name=OPG078;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp063%3B IMV membrane protein%3B similar to VACV-WR I2L and VACV-Cop I2L;gbkey=CDS;gene=OPG078;locus_tag=NBT03_gp057;product=IMV membrane protein I2;protein_id=YP_010377060.1 +NC_063383.1 RefSeq gene 58812 59621 . - . ID=gene-NBT03_gp058;Dbxref=GeneID:72551474;Name=OPG079;gbkey=Gene;gene=OPG079;gene_biotype=protein_coding;locus_tag=NBT03_gp058;old_locus_tag=MPXV-M5312_HM12_Rivers-062 +NC_063383.1 RefSeq CDS 58812 59621 . - 0 ID=cds-YP_010377061.1;Parent=gene-NBT03_gp058;Dbxref=GenBank:YP_010377061.1,GeneID:72551474;Name=OPG079;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp064%3B virosomal ssDNA-binding phosphoprotein%3B interacts with R2 subunit of ribonucleotide reductase%3B similar to VACV-WR I3L and VACV-Cop I3L;gbkey=CDS;gene=OPG079;locus_tag=NBT03_gp058;product=DNA-binding phosphoprotein (2);protein_id=YP_010377061.1 +NC_063383.1 RefSeq gene 59703 62018 . - . ID=gene-NBT03_gp059;Dbxref=GeneID:72551475;Name=OPG080;gbkey=Gene;gene=OPG080;gene_biotype=protein_coding;locus_tag=NBT03_gp059;old_locus_tag=MPXV-M5312_HM12_Rivers-063 +NC_063383.1 RefSeq CDS 59703 62018 . - 0 ID=cds-YP_010377062.1;Parent=gene-NBT03_gp059;Dbxref=GenBank:YP_010377062.1,GeneID:72551475;Name=OPG080;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp065%3B ribonucleotide reductase%2C large subunit%2C R1%3B similar to VACV-WR I4L and VACV-Cop I4L;gbkey=CDS;gene=OPG080;locus_tag=NBT03_gp059;product=Ribonucleoside-diphosphate reductase (2);protein_id=YP_010377062.1 +NC_063383.1 RefSeq gene 62046 62285 . - . ID=gene-NBT03_gp060;Dbxref=GeneID:72551476;Name=OPG081;gbkey=Gene;gene=OPG081;gene_biotype=protein_coding;locus_tag=NBT03_gp060;old_locus_tag=MPXV-M5312_HM12_Rivers-064 +NC_063383.1 RefSeq CDS 62046 62285 . - 0 ID=cds-YP_010377063.1;Parent=gene-NBT03_gp060;Dbxref=GenBank:YP_010377063.1,GeneID:72551476;Name=OPG081;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp066%3B IMV surface membrane protein%2C VP13%3B similar to VACV-WR I5L and VACV-Cop I5L;gbkey=CDS;gene=OPG081;locus_tag=NBT03_gp060;product=IMV membrane protein I5;protein_id=YP_010377063.1 +NC_063383.1 RefSeq gene 62304 63452 . - . ID=gene-NBT03_gp061;Dbxref=GeneID:72551477;Name=OPG082;gbkey=Gene;gene=OPG082;gene_biotype=protein_coding;locus_tag=NBT03_gp061;old_locus_tag=MPXV-M5312_HM12_Rivers-065 +NC_063383.1 RefSeq CDS 62304 63452 . - 0 ID=cds-YP_010377064.1;Parent=gene-NBT03_gp061;Dbxref=GenBank:YP_010377064.1,GeneID:72551477;Name=OPG082;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp067%3B Telomere-binding protein%3B similar to VACV-WR I6L and VACV-Cop I6L;gbkey=CDS;gene=OPG082;locus_tag=NBT03_gp061;product=Telomere-binding protein;protein_id=YP_010377064.1 +NC_063383.1 RefSeq gene 63445 64716 . - . ID=gene-NBT03_gp062;Dbxref=GeneID:72551478;Name=OPG083;gbkey=Gene;gene=OPG083;gene_biotype=protein_coding;locus_tag=NBT03_gp062;old_locus_tag=MPXV-M5312_HM12_Rivers-066 +NC_063383.1 RefSeq CDS 63445 64716 . - 0 ID=cds-YP_010377065.1;Parent=gene-NBT03_gp062;Dbxref=GenBank:YP_010377065.1,GeneID:72551478;Name=OPG083;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp068%3B virion core protein%3B similar to DNA topoisomerase II%3B Virion core cysteine protease%3B similar to VACV-WR I7L and VACV-Cop I7L;gbkey=CDS;gene=OPG083;locus_tag=NBT03_gp062;product=Viral core cysteine proteinase;protein_id=YP_010377065.1 +NC_063383.1 RefSeq gene 64722 66752 . + . ID=gene-NBT03_gp063;Dbxref=GeneID:72551479;Name=OPG084;gbkey=Gene;gene=OPG084;gene_biotype=protein_coding;locus_tag=NBT03_gp063;old_locus_tag=MPXV-M5312_HM12_Rivers-067 +NC_063383.1 RefSeq CDS 64722 66752 . + 0 ID=cds-YP_010377066.1;Parent=gene-NBT03_gp063;Dbxref=GenBank:YP_010377066.1,GeneID:72551479;Name=OPG084;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp069%3B nucleoside triphosphate phosphohydrolase II%2C NPH-II%3B DNA and RNA helicase%3B DExH-NPH-II domain%3B similar to VACV-WR I8R and VACV-Cop I8R;gbkey=CDS;gene=OPG084;locus_tag=NBT03_gp063;product=RNA helicase NPH-II (2);protein_id=YP_010377066.1 +NC_063383.1 RefSeq gene 66756 68531 . - . ID=gene-NBT03_gp064;Dbxref=GeneID:72551480;Name=OPG085;gbkey=Gene;gene=OPG085;gene_biotype=protein_coding;locus_tag=NBT03_gp064;old_locus_tag=MPXV-M5312_HM12_Rivers-068 +NC_063383.1 RefSeq CDS 66756 68531 . - 0 ID=cds-YP_010377067.1;Parent=gene-NBT03_gp064;Dbxref=GenBank:YP_010377067.1,GeneID:72551480;Name=OPG085;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp070%3B proteinase%3B Metalloprotease%3B similar to VACV-WR G1L and VACV-Cop G1L;gbkey=CDS;gene=OPG085;locus_tag=NBT03_gp064;product=Metalloendopeptidase;protein_id=YP_010377067.1 +NC_063383.1 RefSeq gene 68528 68863 . - . ID=gene-NBT03_gp065;Dbxref=GeneID:72551481;Name=OPG086;gbkey=Gene;gene=OPG086;gene_biotype=protein_coding;locus_tag=NBT03_gp065;old_locus_tag=MPXV-M5312_HM12_Rivers-069 +NC_063383.1 RefSeq CDS 68528 68863 . - 0 ID=cds-YP_010377068.1;Parent=gene-NBT03_gp065;Dbxref=GenBank:YP_010377068.1,GeneID:72551481;Name=OPG086;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp071%3B Entry/fusion complex component%3B similar to VACV-WR G2L and VACV-Cop G3L;gbkey=CDS;gene=OPG086;locus_tag=NBT03_gp065;product=Entry/fusion complex component;protein_id=YP_010377068.1 +NC_063383.1 RefSeq gene 68857 69519 . + . ID=gene-NBT03_gp066;Dbxref=GeneID:72551482;Name=OPG087;gbkey=Gene;gene=OPG087;gene_biotype=protein_coding;locus_tag=NBT03_gp066;old_locus_tag=MPXV-M5312_HM12_Rivers-070 +NC_063383.1 RefSeq CDS 68857 69519 . + 0 ID=cds-YP_010377069.1;Parent=gene-NBT03_gp066;Dbxref=GenBank:YP_010377069.1,GeneID:72551482;Name=OPG087;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp072%3B VLTF (late transcription elongation factor)%3B similar to VACV-WR G3R and VACV-Cop G2R;gbkey=CDS;gene=OPG087;locus_tag=NBT03_gp066;product=Late transcription elongation factor;protein_id=YP_010377069.1 +NC_063383.1 RefSeq gene 69489 69863 . - . ID=gene-NBT03_gp067;Dbxref=GeneID:72551483;Name=OPG088;gbkey=Gene;gene=OPG088;gene_biotype=protein_coding;locus_tag=NBT03_gp067;old_locus_tag=MPXV-M5312_HM12_Rivers-071 +NC_063383.1 RefSeq CDS 69489 69863 . - 0 ID=cds-YP_010377070.1;Parent=gene-NBT03_gp067;Dbxref=GenBank:YP_010377070.1,GeneID:72551483;Name=OPG088;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp073%3B virion-associated glutaredoxin%3B Glutaredoxin-like protein%3B similar to VACV-WR G4L and VACV-Cop G4L;gbkey=CDS;gene=OPG088;locus_tag=NBT03_gp067;product=Glutaredoxin-2;protein_id=YP_010377070.1 +NC_063383.1 RefSeq gene 69866 71170 . + . ID=gene-NBT03_gp068;Dbxref=GeneID:72551484;Name=OPG089;gbkey=Gene;gene=OPG089;gene_biotype=protein_coding;locus_tag=NBT03_gp068;old_locus_tag=MPXV-M5312_HM12_Rivers-072 +NC_063383.1 RefSeq CDS 69866 71170 . + 0 ID=cds-YP_010377071.1;Parent=gene-NBT03_gp068;Dbxref=GenBank:YP_010377071.1,GeneID:72551484;Name=OPG089;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp074%3B FEN1-like nuclease%3B similar to VACV-WR G5R and VACV-Cop G5R;gbkey=CDS;gene=OPG089;locus_tag=NBT03_gp068;product=FEN1-like nuclease;protein_id=YP_010377071.1 +NC_063383.1 RefSeq gene 71179 71370 . + . ID=gene-NBT03_gp069;Dbxref=GeneID:72551485;Name=OPG090;gbkey=Gene;gene=OPG090;gene_biotype=protein_coding;locus_tag=NBT03_gp069;old_locus_tag=MPXV-M5312_HM12_Rivers-073 +NC_063383.1 RefSeq CDS 71179 71370 . + 0 ID=cds-YP_010377072.1;Parent=gene-NBT03_gp069;Dbxref=GenBank:YP_010377072.1,GeneID:72551485;Name=OPG090;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp075%3B RNA polymerase subunit%2C 7 kDa subunit (RPO7)%3B similar to VACV-WR G6R and VACV-Cop G5.5R;gbkey=CDS;gene=OPG090;locus_tag=NBT03_gp069;product=DNA-directed RNA polymerase 7 kDa subunit;protein_id=YP_010377072.1 +NC_063383.1 RefSeq gene 71370 71867 . + . ID=gene-NBT03_gp070;Dbxref=GeneID:72551486;Name=OPG091;gbkey=Gene;gene=OPG091;gene_biotype=protein_coding;locus_tag=NBT03_gp070;old_locus_tag=MPXV-M5312_HM12_Rivers-074 +NC_063383.1 RefSeq CDS 71370 71867 . + 0 ID=cds-YP_010377073.1;Parent=gene-NBT03_gp070;Dbxref=GenBank:YP_010377073.1,GeneID:72551486;Name=OPG091;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp076%3B NLPc/P60 superfamily protein%3B similar to VACV-WR G7R and VACV-Cop G6R;gbkey=CDS;gene=OPG091;locus_tag=NBT03_gp070;product=Nlpc/p60 superfamily protein;protein_id=YP_010377073.1 +NC_063383.1 RefSeq gene 71832 72947 . - . ID=gene-NBT03_gp071;Dbxref=GeneID:72551487;Name=OPG092;gbkey=Gene;gene=OPG092;gene_biotype=protein_coding;locus_tag=NBT03_gp071;old_locus_tag=MPXV-M5312_HM12_Rivers-075 +NC_063383.1 RefSeq CDS 71832 72947 . - 0 ID=cds-YP_010377074.1;Parent=gene-NBT03_gp071;Dbxref=GenBank:YP_010377074.1,GeneID:72551487;Name=OPG092;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp077%3B virion protein%3B Virion phosphoprotein%2C early morphogenesis%3B similar to VACV-WR G8L and VACV-Cop G7L;gbkey=CDS;gene=OPG092;locus_tag=NBT03_gp071;product=Assembly protein G7;protein_id=YP_010377074.1 +NC_063383.1 RefSeq gene 72978 73760 . + . ID=gene-NBT03_gp072;Dbxref=GeneID:72551488;Name=OPG093;gbkey=Gene;gene=OPG093;gene_biotype=protein_coding;locus_tag=NBT03_gp072;old_locus_tag=MPXV-M5312_HM12_Rivers-076 +NC_063383.1 RefSeq CDS 72978 73760 . + 0 ID=cds-YP_010377075.1;Parent=gene-NBT03_gp072;Dbxref=GenBank:YP_010377075.1,GeneID:72551488;Name=OPG093;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp078%3B late gene transcription factor%2C VLTF-1%3B similar to VACV-WR G9R and VACV-Cop G8R;gbkey=CDS;gene=OPG093;locus_tag=NBT03_gp072;product=Late transcription factor VLTF-1;protein_id=YP_010377075.1 +NC_063383.1 RefSeq gene 73780 74802 . + . ID=gene-NBT03_gp073;Dbxref=GeneID:72551489;Name=OPG094;gbkey=Gene;gene=OPG094;gene_biotype=protein_coding;locus_tag=NBT03_gp073;old_locus_tag=MPXV-M5312_HM12_Rivers-077 +NC_063383.1 RefSeq CDS 73780 74802 . + 0 ID=cds-YP_010377076.1;Parent=gene-NBT03_gp073;Dbxref=GenBank:YP_010377076.1,GeneID:72551489;Name=OPG094;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp079%3B myristylated protein%3B Entry/fusion complex component%2C myristylprotein%3B similar to VACV-WR G10R and VACV-Cop G9R;gbkey=CDS;gene=OPG094;locus_tag=NBT03_gp073;product=Myristylated protein;protein_id=YP_010377076.1 +NC_063383.1 RefSeq gene 74803 75555 . + . ID=gene-NBT03_gp074;Dbxref=GeneID:72551490;Name=OPG095;gbkey=Gene;gene=OPG095;gene_biotype=protein_coding;locus_tag=NBT03_gp074;old_locus_tag=MPXV-M5312_HM12_Rivers-078 +NC_063383.1 RefSeq CDS 74803 75555 . + 0 ID=cds-YP_010377077.1;Parent=gene-NBT03_gp074;Dbxref=GenBank:YP_010377077.1,GeneID:72551490;Name=OPG095;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp080%3B myristylated IMV surface membrane protein%3B similar to VACV-WR M1R and VACV-Cop L1R;gbkey=CDS;gene=OPG095;locus_tag=NBT03_gp074;product=IMV membrane protein L1R;protein_id=YP_010377077.1 +NC_063383.1 RefSeq gene 75587 75865 . + . ID=gene-NBT03_gp075;Dbxref=GeneID:72551491;Name=OPG096;gbkey=Gene;gene=OPG096;gene_biotype=protein_coding;locus_tag=NBT03_gp075;old_locus_tag=MPXV-M5312_HM12_Rivers-079 +NC_063383.1 RefSeq CDS 75587 75865 . + 0 ID=cds-YP_010377078.1;Parent=gene-NBT03_gp075;Dbxref=GenBank:YP_010377078.1,GeneID:72551491;Name=OPG096;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp081%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR M2R and VACV-Cop L2R;gbkey=CDS;gene=OPG096;locus_tag=NBT03_gp075;product=Crescent membrane and immature virion formation protein;protein_id=YP_010377078.1 +NC_063383.1 RefSeq gene 75841 76875 . - . ID=gene-NBT03_gp076;Dbxref=GeneID:72551492;Name=OPG097;gbkey=Gene;gene=OPG097;gene_biotype=protein_coding;locus_tag=NBT03_gp076;old_locus_tag=MPXV-M5312_HM12_Rivers-080 +NC_063383.1 RefSeq CDS 75841 76875 . - 0 ID=cds-YP_010377079.1;Parent=gene-NBT03_gp076;Dbxref=GenBank:YP_010377079.1,GeneID:72551492;Name=OPG097;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp082%3B Internal virion protein%3B similar to VACV-WR M3L and VACV-Cop L3L;gbkey=CDS;gene=OPG097;locus_tag=NBT03_gp076;product=Internal virion L3/FP4 protein;protein_id=YP_010377079.1 +NC_063383.1 RefSeq gene 76900 77655 . + . ID=gene-NBT03_gp077;Dbxref=GeneID:72551493;Name=OPG098;gbkey=Gene;gene=OPG098;gene_biotype=protein_coding;locus_tag=NBT03_gp077;old_locus_tag=MPXV-M5312_HM12_Rivers-081 +NC_063383.1 RefSeq CDS 76900 77655 . + 0 ID=cds-YP_010377080.1;Parent=gene-NBT03_gp077;Dbxref=GenBank:YP_010377080.1,GeneID:72551493;Name=OPG098;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp083%3B virion core protein vp8%3B stimulation of I8R helicase activity%3B ss/dsDNA binding protein (VP8)%3B similar to VACV-WR M4R and VACV-Cop L4R;gbkey=CDS;gene=OPG098;locus_tag=NBT03_gp077;product=Nucleic acid binding protein VP8/L4R;protein_id=YP_010377080.1 +NC_063383.1 RefSeq gene 77665 78051 . + . ID=gene-NBT03_gp078;Dbxref=GeneID:72551494;Name=OPG099;gbkey=Gene;gene=OPG099;gene_biotype=protein_coding;locus_tag=NBT03_gp078;old_locus_tag=MPXV-M5312_HM12_Rivers-082 +NC_063383.1 RefSeq CDS 77665 78051 . + 0 ID=cds-YP_010377081.1;Parent=gene-NBT03_gp078;Dbxref=GenBank:YP_010377081.1,GeneID:72551494;Name=OPG099;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp084%3B Entry and Fusion IMV protein%3B similar to VACV-WR M5R and VACV-Cop L5R;gbkey=CDS;gene=OPG099;locus_tag=NBT03_gp078;product=Membrane protein CL5;protein_id=YP_010377081.1 +NC_063383.1 RefSeq gene 78008 78466 . + . ID=gene-NBT03_gp079;Dbxref=GeneID:72551495;Name=OPG100;gbkey=Gene;gene=OPG100;gene_biotype=protein_coding;locus_tag=NBT03_gp079;old_locus_tag=MPXV-M5312_HM12_Rivers-083 +NC_063383.1 RefSeq CDS 78008 78466 . + 0 ID=cds-YP_010377082.1;Parent=gene-NBT03_gp079;Dbxref=GenBank:YP_010377082.1,GeneID:72551495;Name=OPG100;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp085%3B Virion morph%3B similar to VACV-WR L1R and VACV-Cop J1R;gbkey=CDS;gene=OPG100;locus_tag=NBT03_gp079;product=IMV membrane protein J1;protein_id=YP_010377082.1 +NC_063383.1 RefSeq gene 78486 79019 . + . ID=gene-NBT03_gp080;Dbxref=GeneID:72551496;Name=OPG101;gbkey=Gene;gene=OPG101;gene_biotype=protein_coding;locus_tag=NBT03_gp080;old_locus_tag=MPXV-M5312_HM12_Rivers-084 +NC_063383.1 RefSeq CDS 78486 79019 . + 0 ID=cds-YP_010377083.1;Parent=gene-NBT03_gp080;Dbxref=GenBank:YP_010377083.1,GeneID:72551496;Name=OPG101;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp086%3B thymidine kinase%3B similar to VACV-WR L2R and VACV-Cop J2R;gbkey=CDS;gene=OPG101;locus_tag=NBT03_gp080;product=Thymidine kinase;protein_id=YP_010377083.1 +NC_063383.1 RefSeq gene 79085 80086 . + . ID=gene-NBT03_gp081;Dbxref=GeneID:72551497;Name=OPG102;gbkey=Gene;gene=OPG102;gene_biotype=protein_coding;locus_tag=NBT03_gp081;old_locus_tag=MPXV-M5312_HM12_Rivers-085 +NC_063383.1 RefSeq CDS 79085 80086 . + 0 ID=cds-YP_010377084.1;Parent=gene-NBT03_gp081;Dbxref=GenBank:YP_010377084.1,GeneID:72551497;Name=OPG102;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp087%3B poly-A polymerase%2C stimulatory subunit%2C simultaneously cap-specific mRNA (nucleoside-O2'-)-methyltransferase%3B Poly (A) polymerase small subunit (VP39)%3B similar to VACV-WR L3R and VACV-Cop J3R;gbkey=CDS;gene=OPG102;locus_tag=NBT03_gp081;product=Cap-specific mRNA;protein_id=YP_010377084.1 +NC_063383.1 RefSeq gene 80001 80558 . + . ID=gene-NBT03_gp082;Dbxref=GeneID:72551498;Name=OPG103;gbkey=Gene;gene=OPG103;gene_biotype=protein_coding;locus_tag=NBT03_gp082;old_locus_tag=MPXV-M5312_HM12_Rivers-086 +NC_063383.1 RefSeq CDS 80001 80558 . + 0 ID=cds-YP_010377085.1;Parent=gene-NBT03_gp082;Dbxref=GenBank:YP_010377085.1,GeneID:72551498;Name=OPG103;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp088%3B RNA polymerase%2C 22 kDa subunit (RPO22)%3B similar to VACV-WR L4R and VACV-Cop J4R;gbkey=CDS;gene=OPG103;locus_tag=NBT03_gp082;product=DNA-directed RNA polymerase subunit;protein_id=YP_010377085.1 +NC_063383.1 RefSeq gene 80618 81019 . - . ID=gene-NBT03_gp083;Dbxref=GeneID:72551499;Name=OPG104;gbkey=Gene;gene=OPG104;gene_biotype=protein_coding;locus_tag=NBT03_gp083;old_locus_tag=MPXV-M5312_HM12_Rivers-087 +NC_063383.1 RefSeq CDS 80618 81019 . - 0 ID=cds-YP_010377086.1;Parent=gene-NBT03_gp083;Dbxref=GenBank:YP_010377086.1,GeneID:72551499;Name=OPG104;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp089%3B essential for virus multiplication%3B IMV membrane protein%3B similar to VACV-WR L5L and VACV-Cop J5L;gbkey=CDS;gene=OPG104;locus_tag=NBT03_gp083;product=Myristylated protein;protein_id=YP_010377086.1 +NC_063383.1 RefSeq gene 81126 84986 . + . ID=gene-NBT03_gp084;Dbxref=GeneID:72551500;Name=OPG105;gbkey=Gene;gene=OPG105;gene_biotype=protein_coding;locus_tag=NBT03_gp084;old_locus_tag=MPXV-M5312_HM12_Rivers-088 +NC_063383.1 RefSeq CDS 81126 84986 . + 0 ID=cds-YP_010377087.1;Parent=gene-NBT03_gp084;Dbxref=GenBank:YP_010377087.1,GeneID:72551500;Name=OPG105;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp090%3B RNA polymerase%2C 147 kDa subunit (RPO147)%3B similar to VACV-WR L6R and VACV-Cop J6R;gbkey=CDS;gene=OPG105;locus_tag=NBT03_gp084;product=DNA-dependent RNA polymerase subunit rpo147;protein_id=YP_010377087.1 +NC_063383.1 RefSeq gene 84983 85498 . - . ID=gene-NBT03_gp085;Dbxref=GeneID:72551501;Name=OPG106;gbkey=Gene;gene=OPG106;gene_biotype=protein_coding;locus_tag=NBT03_gp085;old_locus_tag=MPXV-M5312_HM12_Rivers-089 +NC_063383.1 RefSeq CDS 84983 85498 . - 0 ID=cds-YP_010377088.1;Parent=gene-NBT03_gp085;Dbxref=GenBank:YP_010377088.1,GeneID:72551501;Name=OPG106;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp091%3B tyrosine%3B Tyr/Ser phosphatase%2C IFN-gamma inhibitor%3B similar to VACV-WR H1L and VACV-Cop H1L;gbkey=CDS;gene=OPG106;locus_tag=NBT03_gp085;product=Tyr/ser protein phosphatase;protein_id=YP_010377088.1 +NC_063383.1 RefSeq gene 85512 86081 . + . ID=gene-NBT03_gp086;Dbxref=GeneID:72551502;Name=OPG107;gbkey=Gene;gene=OPG107;gene_biotype=protein_coding;locus_tag=NBT03_gp086;old_locus_tag=MPXV-M5312_HM12_Rivers-090 +NC_063383.1 RefSeq CDS 85512 86081 . + 0 ID=cds-YP_010377089.1;Parent=gene-NBT03_gp086;Dbxref=GenBank:YP_010377089.1,GeneID:72551502;Name=OPG107;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp092%3B IMV membrane protein%3B similar to VACV-WR H2R and VACV-Cop H2R;gbkey=CDS;gene=OPG107;locus_tag=NBT03_gp086;product=Entry-fusion complex essential component;protein_id=YP_010377089.1 +NC_063383.1 RefSeq gene 86085 87059 . - . ID=gene-NBT03_gp087;Dbxref=GeneID:72551503;Name=OPG108;gbkey=Gene;gene=OPG108;gene_biotype=protein_coding;locus_tag=NBT03_gp087;old_locus_tag=MPXV-M5312_HM12_Rivers-091 +NC_063383.1 RefSeq CDS 86085 87059 . - 0 ID=cds-YP_010377090.1;Parent=gene-NBT03_gp087;Dbxref=GenBank:YP_010377090.1,GeneID:72551503;Name=OPG108;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp093%3B IMV surface membrane protein%3B IMV heparin binding surface protein%3B similar to VACV-WR H3L and VACV-Cop H3L;gbkey=CDS;gene=OPG108;locus_tag=NBT03_gp087;product=IMV heparin binding surface protein;protein_id=YP_010377090.1 +NC_063383.1 RefSeq gene 87060 89447 . - . ID=gene-NBT03_gp088;Dbxref=GeneID:72551504;Name=OPG109;gbkey=Gene;gene=OPG109;gene_biotype=protein_coding;locus_tag=NBT03_gp088;old_locus_tag=MPXV-M5312_HM12_Rivers-092 +NC_063383.1 RefSeq CDS 87060 89447 . - 0 ID=cds-YP_010377091.1;Parent=gene-NBT03_gp088;Dbxref=GenBank:YP_010377091.1,GeneID:72551504;Name=OPG109;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp094%3B virion core RNA polymerase-associated protein%2C RAP94%3B similar to VACV-WR H4L and VACV-Cop H4L;gbkey=CDS;gene=OPG109;locus_tag=NBT03_gp088;product=RNA polymerase-associated transcription-specificity factor RAP94;protein_id=YP_010377091.1 +NC_063383.1 RefSeq gene 89632 90264 . + . ID=gene-NBT03_gp089;Dbxref=GeneID:72551505;Name=OPG110;gbkey=Gene;gene=OPG110;gene_biotype=protein_coding;locus_tag=NBT03_gp089;old_locus_tag=MPXV-M5312_HM12_Rivers-093 +NC_063383.1 RefSeq CDS 89632 90264 . + 0 ID=cds-YP_010377092.1;Parent=gene-NBT03_gp089;Dbxref=GenBank:YP_010377092.1,GeneID:72551505;Name=OPG110;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp095%3B virosome-associated late gene transcription factor%2C VLTF-4%3B Ca2+-binding motif%3B similar to VACV-WR H5R and VACV-Cop H5R;gbkey=CDS;gene=OPG110;locus_tag=NBT03_gp089;product=Late transcription factor VLTF-4 (1);protein_id=YP_010377092.1 +NC_063383.1 RefSeq gene 90265 91209 . + . ID=gene-NBT03_gp090;Dbxref=GeneID:72551506;Name=OPG111;gbkey=Gene;gene=OPG111;gene_biotype=protein_coding;locus_tag=NBT03_gp090;old_locus_tag=MPXV-M5312_HM12_Rivers-094 +NC_063383.1 RefSeq CDS 90265 91209 . + 0 ID=cds-YP_010377093.1;Parent=gene-NBT03_gp090;Dbxref=GenBank:YP_010377093.1,GeneID:72551506;Name=OPG111;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp096%3B DNA topoisomerase type I%3B similar to VACV-WR H6R and VACV-Cop H6R;gbkey=CDS;gene=OPG111;locus_tag=NBT03_gp090;product=DNA topoisomerase type I;protein_id=YP_010377093.1 +NC_063383.1 RefSeq gene 91247 91687 . + . ID=gene-NBT03_gp091;Dbxref=GeneID:72551507;Name=OPG112;gbkey=Gene;gene=OPG112;gene_biotype=protein_coding;locus_tag=NBT03_gp091;old_locus_tag=MPXV-M5312_HM12_Rivers-095 +NC_063383.1 RefSeq CDS 91247 91687 . + 0 ID=cds-YP_010377094.1;Parent=gene-NBT03_gp091;Dbxref=GenBank:YP_010377094.1,GeneID:72551507;Name=OPG112;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp097%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR H7R and VACV-Cop H7R;gbkey=CDS;gene=OPG112;locus_tag=NBT03_gp091;product=Late protein H7;protein_id=YP_010377094.1 +NC_063383.1 RefSeq gene 91731 94268 . + . ID=gene-NBT03_gp092;Dbxref=GeneID:72551508;Name=OPG113;gbkey=Gene;gene=OPG113;gene_biotype=protein_coding;locus_tag=NBT03_gp092;old_locus_tag=MPXV-M5312_HM12_Rivers-096 +NC_063383.1 RefSeq CDS 91731 94268 . + 0 ID=cds-YP_010377095.1;Parent=gene-NBT03_gp092;Dbxref=GenBank:YP_010377095.1,GeneID:72551508;Name=OPG113;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp098%3B mRNA capping enzyme%2C large subunit%3B RNA 5' triphosphatase and RNA guanylyl transferase activities%3B similar to VACV-WR E1R and VACV-Cop D1R;gbkey=CDS;gene=OPG113;locus_tag=NBT03_gp092;product=mRNA capping enzyme large subunit;protein_id=YP_010377095.1 +NC_063383.1 RefSeq gene 94227 94667 . - . ID=gene-NBT03_gp093;Dbxref=GeneID:72551509;Name=OPG114;gbkey=Gene;gene=OPG114;gene_biotype=protein_coding;locus_tag=NBT03_gp093;old_locus_tag=MPXV-M5312_HM12_Rivers-097 +NC_063383.1 RefSeq CDS 94227 94667 . - 0 ID=cds-YP_010377096.1;Parent=gene-NBT03_gp093;Dbxref=GenBank:YP_010377096.1,GeneID:72551509;Name=OPG114;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp099%3B virion core protein%3B similar to VACV-WR E2L and VACV-Cop D2L;gbkey=CDS;gene=OPG114;locus_tag=NBT03_gp093;product=Virion protein D2;protein_id=YP_010377096.1 +NC_063383.1 RefSeq gene 94660 95361 . + . ID=gene-NBT03_gp094;Dbxref=GeneID:72551510;Name=OPG115;gbkey=Gene;gene=OPG115;gene_biotype=protein_coding;locus_tag=NBT03_gp094;old_locus_tag=MPXV-M5312_HM12_Rivers-098 +NC_063383.1 RefSeq CDS 94660 95361 . + 0 ID=cds-YP_010377097.1;Parent=gene-NBT03_gp094;Dbxref=GenBank:YP_010377097.1,GeneID:72551510;Name=OPG115;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp100%3B virion core protein%3B similar to VACV-WR E3R and VACV-Cop D3R;gbkey=CDS;gene=OPG115;locus_tag=NBT03_gp094;product=Virion core protein D3;protein_id=YP_010377097.1 +NC_063383.1 RefSeq gene 95361 96017 . + . ID=gene-NBT03_gp095;Dbxref=GeneID:72551511;Name=OPG116;gbkey=Gene;gene=OPG116;gene_biotype=protein_coding;locus_tag=NBT03_gp095;old_locus_tag=MPXV-M5312_HM12_Rivers-099 +NC_063383.1 RefSeq CDS 95361 96017 . + 0 ID=cds-YP_010377098.1;Parent=gene-NBT03_gp095;Dbxref=GenBank:YP_010377098.1,GeneID:72551511;Name=OPG116;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp101%3B uracil DNA glycosylase%3B DNA polymerase processivity factor%3B similar to VACV-WR E4R and VACV-Cop D4R;gbkey=CDS;gene=OPG116;locus_tag=NBT03_gp095;product=Uracil DNA glycosylase superfamily;protein_id=YP_010377098.1 +NC_063383.1 RefSeq gene 96049 98406 . + . ID=gene-NBT03_gp096;Dbxref=GeneID:72551512;Name=OPG117;gbkey=Gene;gene=OPG117;gene_biotype=protein_coding;locus_tag=NBT03_gp096;old_locus_tag=MPXV-M5312_HM12_Rivers-100 +NC_063383.1 RefSeq CDS 96049 98406 . + 0 ID=cds-YP_010377099.1;Parent=gene-NBT03_gp096;Dbxref=GenBank:YP_010377099.1,GeneID:72551512;Name=OPG117;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp102%3B nucleic acid-independent nucleoside triphosphatase%3B NTPase%2C DNA primase%3B similar to VACV-WR E5R and VACV-Cop D5R;gbkey=CDS;gene=OPG117;locus_tag=NBT03_gp096;product=NTPase (1);protein_id=YP_010377099.1 +NC_063383.1 RefSeq gene 98446 100359 . + . ID=gene-NBT03_gp097;Dbxref=GeneID:72551513;Name=OPG118;gbkey=Gene;gene=OPG118;gene_biotype=protein_coding;locus_tag=NBT03_gp097;old_locus_tag=MPXV-M5312_HM12_Rivers-101 +NC_063383.1 RefSeq CDS 98446 100359 . + 0 ID=cds-YP_010377100.1;Parent=gene-NBT03_gp097;Dbxref=GenBank:YP_010377100.1,GeneID:72551513;Name=OPG118;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp103%3B early transcription factor%2C small subunit%2C VETF-s%3B Morphogenesis%3B similar to VACV-WR E6R and VACV-Cop D6R;gbkey=CDS;gene=OPG118;locus_tag=NBT03_gp097;product=Early transcription factor 70 kDa subunit;protein_id=YP_010377100.1 +NC_063383.1 RefSeq gene 100386 100871 . + . ID=gene-NBT03_gp098;Dbxref=GeneID:72551514;Name=OPG119;gbkey=Gene;gene=OPG119;gene_biotype=protein_coding;locus_tag=NBT03_gp098;old_locus_tag=MPXV-M5312_HM12_Rivers-102 +NC_063383.1 RefSeq CDS 100386 100871 . + 0 ID=cds-YP_010377101.1;Parent=gene-NBT03_gp098;Dbxref=GenBank:YP_010377101.1,GeneID:72551514;Name=OPG119;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp104%3B RNA polymerase%2C 18 kDa subunit (RPO18)%3B similar to VACV-WR E7R and VACV-Cop D7R;gbkey=CDS;gene=OPG119;locus_tag=NBT03_gp098;product=RNA polymerase subunit RPO18;protein_id=YP_010377101.1 +NC_063383.1 RefSeq gene 100834 101748 . - . ID=gene-NBT03_gp099;Dbxref=GeneID:72551515;Name=OPG120;gbkey=Gene;gene=OPG120;gene_biotype=protein_coding;locus_tag=NBT03_gp099;old_locus_tag=MPXV-M5312_HM12_Rivers-103 +NC_063383.1 RefSeq CDS 100834 101748 . - 0 ID=cds-YP_010377102.1;Parent=gene-NBT03_gp099;Dbxref=GenBank:YP_010377102.1,GeneID:72551515;Name=OPG120;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp105%3B IMV surface membrane 32 kDa protein%3B binding to cell surface chondroitin sulfate%3B IMV adsorption to cell surface%3B GAG-binding IMV membrane protein%3B similar to VACV-WR E8L and VACV-Cop D8L;gbkey=CDS;gene=OPG120;locus_tag=NBT03_gp099;product=Carbonic anhydrase;protein_id=YP_010377102.1 +NC_063383.1 RefSeq gene 101790 102431 . + . ID=gene-NBT03_gp100;Dbxref=GeneID:72551516;Name=OPG121;gbkey=Gene;gene=OPG121;gene_biotype=protein_coding;locus_tag=NBT03_gp100;old_locus_tag=MPXV-M5312_HM12_Rivers-104 +NC_063383.1 RefSeq CDS 101790 102431 . + 0 ID=cds-YP_010377103.1;Parent=gene-NBT03_gp100;Dbxref=GenBank:YP_010377103.1,GeneID:72551516;Name=OPG121;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp106%3B Mut-like%3B mRNA decapping enzyme%3B similar to VACV-WR E9R and VACV-Cop D9R;gbkey=CDS;gene=OPG121;locus_tag=NBT03_gp100;product=NUDIX domain protein;protein_id=YP_010377103.1 +NC_063383.1 RefSeq gene 102428 103174 . + . ID=gene-NBT03_gp101;Dbxref=GeneID:72551517;Name=OPG122;gbkey=Gene;gene=OPG122;gene_biotype=protein_coding;locus_tag=NBT03_gp101;old_locus_tag=MPXV-M5312_HM12_Rivers-105 +NC_063383.1 RefSeq CDS 102428 103174 . + 0 ID=cds-YP_010377104.1;Parent=gene-NBT03_gp101;Dbxref=GenBank:YP_010377104.1,GeneID:72551517;Name=OPG122;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp107%3B down regulation of gene expression%3B Mut-like%3B mRNA decapping enzyme%3B similar to VACV-WR E10R and VACV-Cop D10R;gbkey=CDS;gene=OPG122;locus_tag=NBT03_gp101;product=MutT motif protein;protein_id=YP_010377104.1 +NC_063383.1 RefSeq gene 103175 105070 . - . ID=gene-NBT03_gp102;Dbxref=GeneID:72551518;Name=OPG123;gbkey=Gene;gene=OPG123;gene_biotype=protein_coding;locus_tag=NBT03_gp102;old_locus_tag=MPXV-M5312_HM12_Rivers-106 +NC_063383.1 RefSeq CDS 103175 105070 . - 0 ID=cds-YP_010377105.1;Parent=gene-NBT03_gp102;Dbxref=GenBank:YP_010377105.1,GeneID:72551518;Name=OPG123;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp108%3B nucleoside triphosphate phosphohydrolase I%2C NPH I%3B DNA-dependent ATPase%3B early gene transcription termination factor%3B similar to VACV-WR E11L and VACV-Cop D11L;gbkey=CDS;gene=OPG123;locus_tag=NBT03_gp102;product=Nucleoside triphosphatase I;protein_id=YP_010377105.1 +NC_063383.1 RefSeq gene 105105 105968 . - . ID=gene-NBT03_gp103;Dbxref=GeneID:72551519;Name=OPG124;gbkey=Gene;gene=OPG124;gene_biotype=protein_coding;locus_tag=NBT03_gp103;old_locus_tag=MPXV-M5312_HM12_Rivers-107 +NC_063383.1 RefSeq CDS 105105 105968 . - 0 ID=cds-YP_010377106.1;Parent=gene-NBT03_gp103;Dbxref=GenBank:YP_010377106.1,GeneID:72551519;Name=OPG124;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp109%3B mRNA capping enzyme small subunit%3B mRNA (guanine-N7-)-methyl-transferase%3B transcription initiation factor%3B similar to VACV-WR E12L and VACV-Cop D12L;gbkey=CDS;gene=OPG124;locus_tag=NBT03_gp103;product=mRNA capping enzyme small subunit;protein_id=YP_010377106.1 +NC_063383.1 RefSeq gene 105999 107654 . - . ID=gene-NBT03_gp104;Dbxref=GeneID:72551520;Name=OPG125;gbkey=Gene;gene=OPG125;gene_biotype=protein_coding;locus_tag=NBT03_gp104;old_locus_tag=MPXV-M5312_HM12_Rivers-108 +NC_063383.1 RefSeq CDS 105999 107654 . - 0 ID=cds-YP_010377107.1;Parent=gene-NBT03_gp104;Dbxref=GenBank:YP_010377107.1,GeneID:72551520;Name=OPG125;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp110%3B protein needed for the formation of immature IMV surface membrane%3B Trimeric virion coat protein (rifampicin res)%3B similar to VACV-WR E13L and VACV-Cop D13L;gbkey=CDS;gene=OPG125;locus_tag=NBT03_gp104;product=Rifampicin resistance protein;protein_id=YP_010377107.1 +NC_063383.1 RefSeq gene 107678 108130 . - . ID=gene-NBT03_gp105;Dbxref=GeneID:72551521;Name=OPG126;gbkey=Gene;gene=OPG126;gene_biotype=protein_coding;locus_tag=NBT03_gp105;old_locus_tag=MPXV-M5312_HM12_Rivers-109 +NC_063383.1 RefSeq CDS 107678 108130 . - 0 ID=cds-YP_010377108.1;Parent=gene-NBT03_gp105;Dbxref=GenBank:YP_010377108.1,GeneID:72551521;Name=OPG126;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp111%3B late gene transcription factor%2C VLTF-2%3B similar to VACV-WR A1L and VACV-Cop A1L;gbkey=CDS;gene=OPG126;locus_tag=NBT03_gp105;product=Late transcription factor VLTF-2 (2);protein_id=YP_010377108.1 +NC_063383.1 RefSeq gene 108151 108825 . - . ID=gene-NBT03_gp106;Dbxref=GeneID:72551522;Name=OPG127;gbkey=Gene;gene=OPG127;gene_biotype=protein_coding;locus_tag=NBT03_gp106;old_locus_tag=MPXV-M5312_HM12_Rivers-110 +NC_063383.1 RefSeq CDS 108151 108825 . - 0 ID=cds-YP_010377109.1;Parent=gene-NBT03_gp106;Dbxref=GenBank:YP_010377109.1,GeneID:72551522;Name=OPG127;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp112%3B late gene transcription factor%2C VLTF-3%3B zinc binding%3B similar to VACV-WR A2L and VACV-Cop A2L;gbkey=CDS;gene=OPG127;locus_tag=NBT03_gp106;product=Late transcription factor VLTF-3 (1);protein_id=YP_010377109.1 +NC_063383.1 RefSeq gene 108822 109055 . - . ID=gene-NBT03_gp107;Dbxref=GeneID:72551523;Name=OPG128;gbkey=Gene;gene=OPG128;gene_biotype=protein_coding;locus_tag=NBT03_gp107;old_locus_tag=MPXV-M5312_HM12_Rivers-111 +NC_063383.1 RefSeq CDS 108822 109055 . - 0 ID=cds-YP_010377110.1;Parent=gene-NBT03_gp107;Dbxref=GenBank:YP_010377110.1,GeneID:72551523;Name=OPG128;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp113%3B S-S bond formation pathway protein%3B similar to VACV-WR A3L and VACV-Cop A2.5L;gbkey=CDS;gene=OPG128;locus_tag=NBT03_gp107;product=S-S bond formation pathway protein;protein_id=YP_010377110.1 +NC_063383.1 RefSeq gene 109070 111004 . - . ID=gene-NBT03_gp108;Dbxref=GeneID:72551524;Name=OPG129;gbkey=Gene;gene=OPG129;gene_biotype=protein_coding;locus_tag=NBT03_gp108;old_locus_tag=MPXV-M5312_HM12_Rivers-112 +NC_063383.1 RefSeq CDS 109070 111004 . - 0 ID=cds-YP_010377111.1;Parent=gene-NBT03_gp108;Dbxref=GenBank:YP_010377111.1,GeneID:72551524;Name=OPG129;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp114%3B major virion core protein p4b%3B P4b precursor%3B similar to VACV-WR A4L and VACV-Cop A3L;gbkey=CDS;gene=OPG129;locus_tag=NBT03_gp108;product=Virion core protein P4b;protein_id=YP_010377111.1 +NC_063383.1 RefSeq gene 111057 111902 . - . ID=gene-NBT03_gp109;Dbxref=GeneID:72551525;Name=OPG130;gbkey=Gene;gene=OPG130;gene_biotype=protein_coding;locus_tag=NBT03_gp109;old_locus_tag=MPXV-M5312_HM12_Rivers-113 +NC_063383.1 RefSeq CDS 111057 111902 . - 0 ID=cds-YP_010377112.1;Parent=gene-NBT03_gp109;Dbxref=GenBank:YP_010377112.1,GeneID:72551525;Name=OPG130;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp115%3B 39 kDa immunodominant virion core protein needed for the progression of IV to infectious IMV%3B 39kDa virion core protein%3B similar to VACV-WR A5L and VACV-Cop A4L;gbkey=CDS;gene=OPG130;locus_tag=NBT03_gp109;product=A5L protein-like;protein_id=YP_010377112.1 +NC_063383.1 RefSeq gene 111940 112425 . + . ID=gene-NBT03_gp110;Dbxref=GeneID:72551526;Name=OPG131;gbkey=Gene;gene=OPG131;gene_biotype=protein_coding;locus_tag=NBT03_gp110;old_locus_tag=MPXV-M5312_HM12_Rivers-114 +NC_063383.1 RefSeq CDS 111940 112425 . + 0 ID=cds-YP_010377113.1;Parent=gene-NBT03_gp110;Dbxref=GenBank:YP_010377113.1,GeneID:72551526;Name=OPG131;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp116%3B precursor of RNA polymerase 22 kDa and 21 kDa%3B RNA polymerase subunit (RPO19)%3B similar to VACV-WR A6R and VACV-Cop A5R;gbkey=CDS;gene=OPG131;locus_tag=NBT03_gp110;product=DNA-directed RNA polymerase 19 kDa subunit;protein_id=YP_010377113.1 +NC_063383.1 RefSeq gene 112422 113540 . - . ID=gene-NBT03_gp111;Dbxref=GeneID:72551527;Name=OPG132;gbkey=Gene;gene=OPG132;gene_biotype=protein_coding;locus_tag=NBT03_gp111;old_locus_tag=MPXV-M5312_HM12_Rivers-115 +NC_063383.1 RefSeq CDS 112422 113540 . - 0 ID=cds-YP_010377114.1;Parent=gene-NBT03_gp111;Dbxref=GenBank:YP_010377114.1,GeneID:72551527;Name=OPG132;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp117%3B Viral membrane assembly proteins (VMAP)%2C core protein%3B similar to VACV-WR A7L and VACV-Cop A6L;gbkey=CDS;gene=OPG132;locus_tag=NBT03_gp111;product=Virion morphogenesis protein;protein_id=YP_010377114.1 +NC_063383.1 RefSeq gene 113564 115696 . - . ID=gene-NBT03_gp112;Dbxref=GeneID:72551528;Name=OPG133;gbkey=Gene;gene=OPG133;gene_biotype=protein_coding;locus_tag=NBT03_gp112;old_locus_tag=MPXV-M5312_HM12_Rivers-116 +NC_063383.1 RefSeq CDS 113564 115696 . - 0 ID=cds-YP_010377115.1;Parent=gene-NBT03_gp112;Dbxref=GenBank:YP_010377115.1,GeneID:72551528;Name=OPG133;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp118%3B early transcription factor%2C large subunit%2C VETF-L%3B needed for morphogenesis of the virion core%3B similar to VACV-WR A8L and VACV-Cop A7L;gbkey=CDS;gene=OPG133;locus_tag=NBT03_gp112;product=Early transcription factor 82 kDa subunit;protein_id=YP_010377115.1 +NC_063383.1 RefSeq gene 115750 116628 . + . ID=gene-NBT03_gp113;Dbxref=GeneID:72551529;Name=OPG134;gbkey=Gene;gene=OPG134;gene_biotype=protein_coding;locus_tag=NBT03_gp113;old_locus_tag=MPXV-M5312_HM12_Rivers-117 +NC_063383.1 RefSeq CDS 115750 116628 . + 0 ID=cds-YP_010377116.1;Parent=gene-NBT03_gp113;Dbxref=GenBank:YP_010377116.1,GeneID:72551529;Name=OPG134;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp119%3B intermediate transcription factor%2C VITF-3 34kda subunit%2C 34 kDa%3B similar to VACV-WR A9R and VACV-Cop A8R;gbkey=CDS;gene=OPG134;locus_tag=NBT03_gp113;product=Intermediate transcription factor VITF-3 (1);protein_id=YP_010377116.1 +NC_063383.1 RefSeq gene 116609 116911 . - . ID=gene-NBT03_gp114;Dbxref=GeneID:72551530;Name=OPG135;gbkey=Gene;gene=OPG135;gene_biotype=protein_coding;locus_tag=NBT03_gp114;old_locus_tag=MPXV-M5312_HM12_Rivers-118 +NC_063383.1 RefSeq CDS 116609 116911 . - 0 ID=cds-YP_010377117.1;Parent=gene-NBT03_gp114;Dbxref=GenBank:YP_010377117.1,GeneID:72551530;Name=OPG135;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp120%3B Viral membrane associated%2C early morphogenesis protein%3B similar to VACV-WR A10L and VACV-Cop A9L;gbkey=CDS;gene=OPG135;locus_tag=NBT03_gp114;product=IMV membrane protein A9;protein_id=YP_010377117.1 +NC_063383.1 RefSeq gene 116912 119587 . - . ID=gene-NBT03_gp115;Dbxref=GeneID:72551531;Name=OPG136;gbkey=Gene;gene=OPG136;gene_biotype=protein_coding;locus_tag=NBT03_gp115;old_locus_tag=MPXV-M5312_HM12_Rivers-119 +NC_063383.1 RefSeq CDS 116912 119587 . - 0 ID=cds-YP_010377118.1;Parent=gene-NBT03_gp115;Dbxref=GenBank:YP_010377118.1,GeneID:72551531;Name=OPG136;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp121%3B major virion core protein p4a%3B P4a precursor%3B similar to VACV-WR A11L and VACV-Cop A10L;gbkey=CDS;gene=OPG136;locus_tag=NBT03_gp115;product=Virion core protein P4a;protein_id=YP_010377118.1 +NC_063383.1 RefSeq gene 119602 120558 . + . ID=gene-NBT03_gp116;Dbxref=GeneID:72551532;Name=OPG137;gbkey=Gene;gene=OPG137;gene_biotype=protein_coding;locus_tag=NBT03_gp116;old_locus_tag=MPXV-M5312_HM12_Rivers-120 +NC_063383.1 RefSeq CDS 119602 120558 . + 0 ID=cds-YP_010377119.1;Parent=gene-NBT03_gp116;Dbxref=GenBank:YP_010377119.1,GeneID:72551532;Name=OPG137;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp122%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR A12R and VACV-Cop A11R;gbkey=CDS;gene=OPG137;locus_tag=NBT03_gp116;product=Viral membrane formation protein;protein_id=YP_010377119.1 +NC_063383.1 RefSeq gene 120560 121132 . - . ID=gene-NBT03_gp117;Dbxref=GeneID:72551533;Name=OPG138;gbkey=Gene;gene=OPG138;gene_biotype=protein_coding;locus_tag=NBT03_gp117;old_locus_tag=MPXV-M5312_HM12_Rivers-121 +NC_063383.1 RefSeq CDS 120560 121132 . - 0 ID=cds-YP_010377120.1;Parent=gene-NBT03_gp117;Dbxref=GenBank:YP_010377120.1,GeneID:72551533;Name=OPG138;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp123%3B Virion core and cleavage processing protein%3B similar to VACV-WR A13L and VACV-Cop A12L;gbkey=CDS;gene=OPG138;locus_tag=NBT03_gp117;product=A12 protein;protein_id=YP_010377120.1 +NC_063383.1 RefSeq gene 121156 121368 . - . ID=gene-NBT03_gp118;Dbxref=GeneID:72551534;Name=OPG139;gbkey=Gene;gene=OPG139;gene_biotype=protein_coding;locus_tag=NBT03_gp118;old_locus_tag=MPXV-M5312_HM12_Rivers-122 +NC_063383.1 RefSeq CDS 121156 121368 . - 0 ID=cds-YP_010377121.1;Parent=gene-NBT03_gp118;Dbxref=GenBank:YP_010377121.1,GeneID:72551534;Name=OPG139;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp124%3B IMV inner and outer membrane protein%3B virion maturation%3B similar to VACV-WR A14L and VACV-Cop A13L;gbkey=CDS;gene=OPG139;locus_tag=NBT03_gp118;product=IMV membrane protein A13L;protein_id=YP_010377121.1 +NC_063383.1 RefSeq gene 121474 121746 . - . ID=gene-NBT03_gp119;Dbxref=GeneID:72551535;Name=OPG140;gbkey=Gene;gene=OPG140;gene_biotype=protein_coding;locus_tag=NBT03_gp119;old_locus_tag=MPXV-M5312_HM12_Rivers-123 +NC_063383.1 RefSeq CDS 121474 121746 . - 0 ID=cds-YP_010377122.1;Parent=gene-NBT03_gp119;Dbxref=GenBank:YP_010377122.1,GeneID:72551535;Name=OPG140;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp125%3B IMV inner membrane protein%3B Essential IMV membrane protein%3B similar to VACV-WR A15L and VACV-Cop A14L;gbkey=CDS;gene=OPG140;locus_tag=NBT03_gp119;product=IMV membrane protein A14;protein_id=YP_010377122.1 +NC_063383.1 RefSeq gene 121763 121924 . - . ID=gene-NBT03_gp120;Dbxref=GeneID:72551536;Name=OPG141;gbkey=Gene;gene=OPG141;gene_biotype=protein_coding;locus_tag=NBT03_gp120;old_locus_tag=MPXV-M5312_HM12_Rivers-124 +NC_063383.1 RefSeq CDS 121763 121924 . - 0 ID=cds-YP_010377123.1;Parent=gene-NBT03_gp120;Dbxref=GenBank:YP_010377123.1,GeneID:72551536;Name=OPG141;Note=Taxonomic breadth: chordopoxvirinae%3B Non-essential IMV membrane protein%3B similar to VACV-WR A15.5L and VACV-Cop A14.5L;gbkey=CDS;gene=OPG141;locus_tag=NBT03_gp120;product=DUF1029 domain protein;protein_id=YP_010377123.1 +NC_063383.1 RefSeq gene 121914 122198 . - . ID=gene-NBT03_gp121;Dbxref=GeneID:72551537;Name=OPG142;gbkey=Gene;gene=OPG142;gene_biotype=protein_coding;locus_tag=NBT03_gp121;old_locus_tag=MPXV-M5312_HM12_Rivers-125 +NC_063383.1 RefSeq CDS 121914 122198 . - 0 ID=cds-YP_010377124.1;Parent=gene-NBT03_gp121;Dbxref=GenBank:YP_010377124.1,GeneID:72551537;Name=OPG142;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp126%3B Core protein%3B similar to VACV-WR A16L and VACV-Cop A15L;gbkey=CDS;gene=OPG142;locus_tag=NBT03_gp121;product=Core protein A15;protein_id=YP_010377124.1 +NC_063383.1 RefSeq gene 122182 123315 . - . ID=gene-NBT03_gp122;Dbxref=GeneID:72551538;Name=OPG143;gbkey=Gene;gene=OPG143;gene_biotype=protein_coding;locus_tag=NBT03_gp122;old_locus_tag=MPXV-M5312_HM12_Rivers-126 +NC_063383.1 RefSeq CDS 122182 123315 . - 0 ID=cds-YP_010377125.1;Parent=gene-NBT03_gp122;Dbxref=GenBank:YP_010377125.1,GeneID:72551538;Name=OPG143;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp127%3B soluble myristylated protein%3B essential for entry/fusion%3B similar to VACV-WR A17L and VACV-Cop A16L;gbkey=CDS;gene=OPG143;locus_tag=NBT03_gp122;product=Myristylated protein;protein_id=YP_010377125.1 +NC_063383.1 RefSeq gene 123318 123932 . - . ID=gene-NBT03_gp123;Dbxref=GeneID:72551539;Name=OPG144;gbkey=Gene;gene=OPG144;gene_biotype=protein_coding;locus_tag=NBT03_gp123;old_locus_tag=MPXV-M5312_HM12_Rivers-127 +NC_063383.1 RefSeq CDS 123318 123932 . - 0 ID=cds-YP_010377126.1;Parent=gene-NBT03_gp123;Dbxref=GenBank:YP_010377126.1,GeneID:72551539;Name=OPG144;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp128%3B IMV surface membrane protein%3B early function in virion morphgenesis%3B similar to VACV-WR A18L and VACV-Cop A17L;gbkey=CDS;gene=OPG144;locus_tag=NBT03_gp123;product=IMV membrane protein P21;protein_id=YP_010377126.1 +NC_063383.1 RefSeq gene 123947 125425 . + . ID=gene-NBT03_gp124;Dbxref=GeneID:72551540;Name=OPG145;gbkey=Gene;gene=OPG145;gene_biotype=protein_coding;locus_tag=NBT03_gp124;old_locus_tag=MPXV-M5312_HM12_Rivers-128 +NC_063383.1 RefSeq CDS 123947 125425 . + 0 ID=cds-YP_010377127.1;Parent=gene-NBT03_gp124;Dbxref=GenBank:YP_010377127.1,GeneID:72551540;Name=OPG145;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp129%3B virion core associated DNA helicase%3B post-replicative negative transcription elongation factor%3B transcript release factor%3B similar to VACV-WR A19R and VACV-Cop A18R;gbkey=CDS;gene=OPG145;locus_tag=NBT03_gp124;product=DNA helicase;protein_id=YP_010377127.1 +NC_063383.1 RefSeq gene 125406 125639 . - . ID=gene-NBT03_gp125;Dbxref=GeneID:72551541;Name=OPG146;gbkey=Gene;gene=OPG146;gene_biotype=protein_coding;locus_tag=NBT03_gp125;old_locus_tag=MPXV-M5312_HM12_Rivers-129 +NC_063383.1 RefSeq CDS 125406 125639 . - 0 ID=cds-YP_010377128.1;Parent=gene-NBT03_gp125;Dbxref=GenBank:YP_010377128.1,GeneID:72551541;Name=OPG146;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp130%3B Zinc finger-like protein%3B similar to VACV-WR A20L and VACV-Cop A19L;gbkey=CDS;gene=OPG146;locus_tag=NBT03_gp125;product=Zinc finger-like protein (1);protein_id=YP_010377128.1 +NC_063383.1 RefSeq gene 125640 125987 . - . ID=gene-NBT03_gp126;Dbxref=GeneID:72551542;Name=OPG147;gbkey=Gene;gene=OPG147;gene_biotype=protein_coding;locus_tag=NBT03_gp126;old_locus_tag=MPXV-M5312_HM12_Rivers-130 +NC_063383.1 RefSeq CDS 125640 125987 . - 0 ID=cds-YP_010377129.1;Parent=gene-NBT03_gp126;Dbxref=GenBank:YP_010377129.1,GeneID:72551542;Name=OPG147;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp131%3B IMV membrane protein%2C entry/fusion complex component%3B similar to VACV-WR A21L and VACV-Cop A21L;gbkey=CDS;gene=OPG147;locus_tag=NBT03_gp126;product=IMV membrane protein A21;protein_id=YP_010377129.1 +NC_063383.1 RefSeq gene 125986 127266 . + . ID=gene-NBT03_gp127;Dbxref=GeneID:72551543;Name=OPG148;gbkey=Gene;gene=OPG148;gene_biotype=protein_coding;locus_tag=NBT03_gp127;old_locus_tag=MPXV-M5312_HM12_Rivers-131 +NC_063383.1 RefSeq CDS 125986 127266 . + 0 ID=cds-YP_010377130.1;Parent=gene-NBT03_gp127;Dbxref=GenBank:YP_010377130.1,GeneID:72551543;Name=OPG148;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp132%3B processivity factor for the viral DNA polymerase%2C VPF%3B similar to VACV-WR A22R and VACV-Cop A20R;gbkey=CDS;gene=OPG148;locus_tag=NBT03_gp127;product=DNA polymerase processivity factor;protein_id=YP_010377130.1 +NC_063383.1 RefSeq gene 127196 127759 . + . ID=gene-NBT03_gp128;Dbxref=GeneID:72551544;Name=OPG149;gbkey=Gene;gene=OPG149;gene_biotype=protein_coding;locus_tag=NBT03_gp128;old_locus_tag=MPXV-M5312_HM12_Rivers-132 +NC_063383.1 RefSeq CDS 127196 127759 . + 0 ID=cds-YP_010377131.1;Parent=gene-NBT03_gp128;Dbxref=GenBank:YP_010377131.1,GeneID:72551544;Name=OPG149;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp133%3B Holliday junction resolvase%3B similar to VACV-WR A23R and VACV-Cop A22R;gbkey=CDS;gene=OPG149;locus_tag=NBT03_gp128;product=Holliday junction resolvase;protein_id=YP_010377131.1 +NC_063383.1 RefSeq gene 127779 128927 . + . ID=gene-NBT03_gp129;Dbxref=GeneID:72551545;Name=OPG150;gbkey=Gene;gene=OPG150;gene_biotype=protein_coding;locus_tag=NBT03_gp129;old_locus_tag=MPXV-M5312_HM12_Rivers-133 +NC_063383.1 RefSeq CDS 127779 128927 . + 0 ID=cds-YP_010377132.1;Parent=gene-NBT03_gp129;Dbxref=GenBank:YP_010377132.1,GeneID:72551545;Name=OPG150;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp134%3B intermediate transcription factor%2C VITF-3%2C 45 kDa subunit%3B similar to VACV-WR A24R and VACV-Cop A23R;gbkey=CDS;gene=OPG150;locus_tag=NBT03_gp129;product=Intermediate transcription factor VITF-3 (2);protein_id=YP_010377132.1 +NC_063383.1 RefSeq gene 128924 132418 . + . ID=gene-NBT03_gp130;Dbxref=GeneID:72551546;Name=OPG151;gbkey=Gene;gene=OPG151;gene_biotype=protein_coding;locus_tag=NBT03_gp130;old_locus_tag=MPXV-M5312_HM12_Rivers-134 +NC_063383.1 RefSeq CDS 128924 132418 . + 0 ID=cds-YP_010377133.1;Parent=gene-NBT03_gp130;Dbxref=GenBank:YP_010377133.1,GeneID:72551546;Name=OPG151;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp135%3B RNA polymerase%2C 132 kDa subunit (RPO132)%3B similar to VACV-WR A25R and VACV-Cop A24R;gbkey=CDS;gene=OPG151;locus_tag=NBT03_gp130;product=DNA-dependent RNA polymerase subunit rpo132;protein_id=YP_010377133.1 +NC_063383.1 RefSeq sequence_feature 132396 136092 . - . ID=id-NC_063383.1:132396..136092;exon_number=OPG152;gbkey=misc_feature;number=OPG152 +NC_063383.1 RefSeq gene 136138 137667 . - . ID=gene-NBT03_gp131;Dbxref=GeneID:72551547;Name=OPG153;gbkey=Gene;gene=OPG153;gene_biotype=protein_coding;locus_tag=NBT03_gp131;old_locus_tag=MPXV-M5312_HM12_Rivers-137 +NC_063383.1 RefSeq CDS 136138 137667 . - 0 ID=cds-YP_010377134.1;Parent=gene-NBT03_gp131;Dbxref=GenBank:YP_010377134.1,GeneID:72551547;Name=OPG153;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp138%3B major component of IMV surface tubules%3B A-type inclusion protein%3B P4c precursor%3B similar to VACV-WR A28L and VACV-Cop A26L;gbkey=CDS;gene=OPG153;locus_tag=NBT03_gp131;product=Orthopoxvirus A26L/A30L protein;protein_id=YP_010377134.1 +NC_063383.1 RefSeq gene 137718 138050 . - . ID=gene-NBT03_gp132;Dbxref=GeneID:72551548;Name=OPG154;gbkey=Gene;gene=OPG154;gene_biotype=protein_coding;locus_tag=NBT03_gp132;old_locus_tag=MPXV-M5312_HM12_Rivers-138 +NC_063383.1 RefSeq CDS 137718 138050 . - 0 ID=cds-YP_010377135.1;Parent=gene-NBT03_gp132;Dbxref=GenBank:YP_010377135.1,GeneID:72551548;Name=OPG154;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp139%3B IMV surface membrane 14 kDa fusion protein%3B binding to cell surface heparan%3B similar to VACV-WR A29L and VACV-Cop A27L;gbkey=CDS;gene=OPG154;locus_tag=NBT03_gp132;product=IMV surface fusion protein;protein_id=YP_010377135.1 +NC_063383.1 RefSeq gene 138051 138491 . - . ID=gene-NBT03_gp133;Dbxref=GeneID:72551549;Name=OPG155;gbkey=Gene;gene=OPG155;gene_biotype=protein_coding;locus_tag=NBT03_gp133;old_locus_tag=MPXV-M5312_HM12_Rivers-139 +NC_063383.1 RefSeq CDS 138051 138491 . - 0 ID=cds-YP_010377136.1;Parent=gene-NBT03_gp133;Dbxref=GenBank:YP_010377136.1,GeneID:72551549;Name=OPG155;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp140%3B IMV MP/Virus entry%3B similar to VACV-WR A30L and VACV-Cop A28L;gbkey=CDS;gene=OPG155;locus_tag=NBT03_gp133;product=Envelope protein A28 homolog;protein_id=YP_010377136.1 +NC_063383.1 RefSeq gene 138492 139409 . - . ID=gene-NBT03_gp134;Dbxref=GeneID:72551550;Name=OPG156;gbkey=Gene;gene=OPG156;gene_biotype=protein_coding;locus_tag=NBT03_gp134;old_locus_tag=MPXV-M5312_HM12_Rivers-140 +NC_063383.1 RefSeq CDS 138492 139409 . - 0 ID=cds-YP_010377137.1;Parent=gene-NBT03_gp134;Dbxref=GenBank:YP_010377137.1,GeneID:72551550;Name=OPG156;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp141%3B RNA polymerase%2C 35 kDa subunit (RPO35)%3B similar to VACV-WR A31L and VACV-Cop A29L;gbkey=CDS;gene=OPG156;locus_tag=NBT03_gp134;product=DNA-directed RNA polymerase 35 kDa subunit;protein_id=YP_010377137.1 +NC_063383.1 RefSeq gene 139372 139608 . - . ID=gene-NBT03_gp135;Dbxref=GeneID:72551551;Name=OPG157;gbkey=Gene;gene=OPG157;gene_biotype=protein_coding;locus_tag=NBT03_gp135;old_locus_tag=MPXV-M5312_HM12_Rivers-141 +NC_063383.1 RefSeq CDS 139372 139608 . - 0 ID=cds-YP_010377138.1;Parent=gene-NBT03_gp135;Dbxref=GenBank:YP_010377138.1,GeneID:72551551;Name=OPG157;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp142%3B IMV protein%3B similar to VACV-WR A32L and VACV-Cop A30L;gbkey=CDS;gene=OPG157;locus_tag=NBT03_gp135;product=IMV membrane protein A30;protein_id=YP_010377138.1 +NC_063383.1 RefSeq gene 139641 139769 . - . ID=gene-NBT03_gp136;Dbxref=GeneID:72551552;Name=OPG158;gbkey=Gene;gene=OPG158;gene_biotype=protein_coding;locus_tag=NBT03_gp136;old_locus_tag=MPXV-M5312_HM12_Rivers-142 +NC_063383.1 RefSeq CDS 139641 139769 . - 0 ID=cds-YP_010377139.1;Parent=gene-NBT03_gp136;Dbxref=GenBank:YP_010377139.1,GeneID:72551552;Name=OPG158;Note=Viral membrane assembly proteins (VMAP)%3B similar to VACV-Cop A30.5L;gbkey=CDS;gene=OPG158;locus_tag=NBT03_gp136;product=A32.5L;protein_id=YP_010377139.1 +NC_063383.1 RefSeq gene 139768 140205 . + . ID=gene-NBT03_gp137;Dbxref=GeneID:72551553;Name=OPG159;gbkey=Gene;gene=OPG159;gene_biotype=protein_coding;locus_tag=NBT03_gp137;old_locus_tag=MPXV-M5312_HM12_Rivers-143 +NC_063383.1 RefSeq CDS 139768 140205 . + 0 ID=cds-YP_010377140.1;Parent=gene-NBT03_gp137;Dbxref=GenBank:YP_010377140.1,GeneID:72551553;Name=OPG159;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp143%3B Hypothetical protein%3B similar to VACV-WR A33R and VACV-Cop A31R;gbkey=CDS;gene=OPG159;locus_tag=NBT03_gp137;product=CPXV166 protein;protein_id=YP_010377140.1 +NC_063383.1 RefSeq gene 140172 141074 . - . ID=gene-NBT03_gp138;Dbxref=GeneID:72551554;Name=OPG160;gbkey=Gene;gene=OPG160;gene_biotype=protein_coding;locus_tag=NBT03_gp138;old_locus_tag=MPXV-M5312_HM12_Rivers-144 +NC_063383.1 RefSeq CDS 140172 141074 . - 0 ID=cds-YP_010377141.1;Parent=gene-NBT03_gp138;Dbxref=GenBank:YP_010377141.1,GeneID:72551554;Name=OPG160;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp144%3B DNA packaging into virion%3B NTP-binding motif A%3B ATPase/DNA packaging protein%3B similar to VACV-WR A34L and VACV-Cop A32L;gbkey=CDS;gene=OPG160;locus_tag=NBT03_gp138;product=ATPase A32;protein_id=YP_010377141.1 +NC_063383.1 RefSeq gene 141102 141647 . + . ID=gene-NBT03_gp139;Dbxref=GeneID:72551555;Name=OPG161;gbkey=Gene;gene=OPG161;gene_biotype=protein_coding;locus_tag=NBT03_gp139;old_locus_tag=MPXV-M5312_HM12_Rivers-145 +NC_063383.1 RefSeq CDS 141102 141647 . + 0 ID=cds-YP_010377142.1;Parent=gene-NBT03_gp139;Dbxref=GenBank:YP_010377142.1,GeneID:72551555;Name=OPG161;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp145%3B EEV envelope glycoprotein%2C needed for formation of actin-containing microvilli and cell-to-cell spread of virion%3B interacts with VAC A36R%3B EEV membrane phosphoglycoprotein%2C C-type lectin-like domain%3B similar to VACV-WR A35R and VACV-Cop A33R;gbkey=CDS;gene=OPG161;locus_tag=NBT03_gp139;product=EEV glycoprotein (1);protein_id=YP_010377142.1 +NC_063383.1 RefSeq gene 141652 142158 . + . ID=gene-NBT03_gp140;Dbxref=GeneID:72551556;Name=OPG162;gbkey=Gene;gene=OPG162;gene_biotype=protein_coding;locus_tag=NBT03_gp140;old_locus_tag=MPXV-M5312_HM12_Rivers-146 +NC_063383.1 RefSeq CDS 141652 142158 . + 0 ID=cds-YP_010377143.1;Parent=gene-NBT03_gp140;Dbxref=GenBank:YP_010377143.1,GeneID:72551556;Name=OPG162;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp146%3B EEV envelope glycoprotein%2C lectin-like%3B required for infectivity of EEV%2C formation of actin-containing microvilli%2C and cell-to-cell spread of virion%3B C-type lectin-like IEV/EEV glycoprotein%3B similar to VACV-WR A36R and VACV-Cop A34R;gbkey=CDS;gene=OPG162;locus_tag=NBT03_gp140;product=EEV glycoprotein (2);protein_id=YP_010377143.1 +NC_063383.1 RefSeq gene 142202 142732 . + . ID=gene-NBT03_gp141;Dbxref=GeneID:72551557;Name=OPG163;gbkey=Gene;gene=OPG163;gene_biotype=protein_coding;locus_tag=NBT03_gp141;old_locus_tag=MPXV-M5312_HM12_Rivers-147 +NC_063383.1 RefSeq CDS 142202 142732 . + 0 ID=cds-YP_010377144.1;Parent=gene-NBT03_gp141;Dbxref=GenBank:YP_010377144.1,GeneID:72551557;Name=OPG163;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp147%3B MHC class II antigen presentation inhibitor%3B similar to VACV-WR A37R and VACV-Cop A35R;gbkey=CDS;gene=OPG163;locus_tag=NBT03_gp141;product=MHC class II antigen presentation inhibitor;protein_id=YP_010377144.1 +NC_063383.1 RefSeq gene 142778 143464 . + . ID=gene-NBT03_gp142;Dbxref=GeneID:72551558;Name=OPG164;gbkey=Gene;gene=OPG164;gene_biotype=protein_coding;locus_tag=NBT03_gp142;old_locus_tag=MPXV-M5312_HM12_Rivers-148 +NC_063383.1 RefSeq CDS 142778 143464 . + 0 ID=cds-YP_010377145.1;Parent=gene-NBT03_gp142;Dbxref=GenBank:YP_010377145.1,GeneID:72551558;Name=OPG164;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp148%3B IEV but not CEV envelope protein%3B plays critical role for actin tail formation%3B interacts with VAC A33R and A34R%3B IEV transmembrane phosphoprotein%3B similar to VACV-WR A38R and VACV-Cop A36R;gbkey=CDS;gene=OPG164;locus_tag=NBT03_gp142;product=IEV transmembrane phosphoprotein;protein_id=YP_010377145.1 +NC_063383.1 RefSeq gene 143516 144322 . + . ID=gene-NBT03_gp143;Dbxref=GeneID:72551559;Name=OPG165;gbkey=Gene;gene=OPG165;gene_biotype=protein_coding;locus_tag=NBT03_gp143;old_locus_tag=MPXV-M5312_HM12_Rivers-149 +NC_063383.1 RefSeq CDS 143516 144322 . + 0 ID=cds-YP_010377146.1;Parent=gene-NBT03_gp143;Dbxref=GenBank:YP_010377146.1,GeneID:72551559;Name=OPG165;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp149%3B Hypothetical protein%3B similar to VACV-WR A39R and VACV-Cop A37R;gbkey=CDS;gene=OPG165;locus_tag=NBT03_gp143;product=CPXV173 protein;protein_id=YP_010377146.1 +NC_063383.1 RefSeq gene 144398 144577 . + . ID=gene-NBT03_gp144;Dbxref=GeneID:72551560;Name=OPG166;gbkey=Gene;gene=OPG166;gene_biotype=protein_coding;locus_tag=NBT03_gp144 +NC_063383.1 RefSeq CDS 144398 144577 . + 0 ID=cds-YP_010415322.1;Parent=gene-NBT03_gp144;Dbxref=GenBank:YP_010415322.1,GeneID:72551560;Name=OPG166;Note=Hypothetical protein%3B according to YP_233043.1%2C this VACV-WR protein was purified by sucrose gradient centrifugation%3B similar to VACWR161 and VARGAR-A43R;gbkey=CDS;gene=OPG166;locus_tag=NBT03_gp144;product=hypothetical protein;protein_id=YP_010415322.1 +NC_063383.1 RefSeq gene 144574 145407 . - . ID=gene-NBT03_gp145;Dbxref=GeneID:72551561;Name=OPG167;gbkey=Gene;gene=OPG167;gene_biotype=protein_coding;locus_tag=NBT03_gp145;old_locus_tag=MPXV-M5312_HM12_Rivers-150 +NC_063383.1 RefSeq CDS 144574 145407 . - 0 ID=cds-YP_010377147.1;Parent=gene-NBT03_gp145;Dbxref=GenBank:YP_010377147.1,GeneID:72551561;Name=OPG167;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp150%3B integral membrane glycoprotein%3B immunoglobulin-like%3B regulation of the influx of extracellular Ca2+%3B CD47-like%3B similar to VACV-WR A40L and VACV-Cop A38L;gbkey=CDS;gene=OPG167;locus_tag=NBT03_gp145;product=CD47-like protein;protein_id=YP_010377147.1 +NC_063383.1 RefSeq sequence_feature 145423 145856 . + . ID=id-NC_063383.1:145423..145856;exon_number=OPG168;gbkey=misc_feature;number=OPG168 +NC_063383.1 RefSeq sequence_feature 145857 146039 . + . ID=id-NC_063383.1:145857..146039;exon_number=OPG169;gbkey=misc_feature;number=OPG169 +NC_063383.1 RefSeq gene 146113 146778 . - . ID=gene-NBT03_gp146;Dbxref=GeneID:72551562;Name=OPG170;gbkey=Gene;gene=OPG170;gene_biotype=protein_coding;locus_tag=NBT03_gp146;old_locus_tag=MPXV-M5312_HM12_Rivers-151 +NC_063383.1 RefSeq CDS 146113 146778 . - 0 ID=cds-YP_010377148.1;Parent=gene-NBT03_gp146;Dbxref=GenBank:YP_010377148.1,GeneID:72551562;Name=OPG170;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp151%3B secreted protein reducing infiltration of inflammatory cells into the infected area%3B Chemokine binding protein%3B similar to VACV-WR A41L and VACV-Cop A41L;gbkey=CDS;gene=OPG170;locus_tag=NBT03_gp146;product=Chemokine binding protein;protein_id=YP_010377148.1 +NC_063383.1 RefSeq gene 146988 147389 . + . ID=gene-NBT03_gp147;Dbxref=GeneID:72551563;Name=OPG171;gbkey=Gene;gene=OPG171;gene_biotype=protein_coding;locus_tag=NBT03_gp147;old_locus_tag=MPXV-M5312_HM12_Rivers-152 +NC_063383.1 RefSeq CDS 146988 147389 . + 0 ID=cds-YP_010377149.1;Parent=gene-NBT03_gp147;Dbxref=GenBank:YP_010377149.1,GeneID:72551563;Name=OPG171;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp152%3B Profilin-like protein%2C ATI-localized%3B similar to VACV-WR A42R and VACV-Cop A42R;gbkey=CDS;gene=OPG171;locus_tag=NBT03_gp147;product=Profilin domain protein;protein_id=YP_010377149.1 +NC_063383.1 RefSeq gene 147427 148017 . + . ID=gene-NBT03_gp148;Dbxref=GeneID:72551564;Name=OPG172;gbkey=Gene;gene=OPG172;gene_biotype=protein_coding;locus_tag=NBT03_gp148;old_locus_tag=MPXV-M5312_HM12_Rivers-153 +NC_063383.1 RefSeq CDS 147427 148017 . + 0 ID=cds-YP_010377150.1;Parent=gene-NBT03_gp148;Dbxref=GenBank:YP_010377150.1,GeneID:72551564;Name=OPG172;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp153%3B Type I membrane glycoprotein%3B similar to VACV-WR A43R and VACV-Cop A43R;gbkey=CDS;gene=OPG172;locus_tag=NBT03_gp148;product=Type-I membrane glycoprotein;protein_id=YP_010377150.1 +NC_063383.1 RefSeq gene 148037 148261 . + . ID=gene-NBT03_gp149;Dbxref=GeneID:72551565;Name=OPG173;gbkey=Gene;gene=OPG173;gene_biotype=protein_coding;locus_tag=NBT03_gp149;old_locus_tag=MPXV-M5312_HM12_Rivers-154 +NC_063383.1 RefSeq CDS 148037 148261 . + 0 ID=cds-YP_010377151.1;Parent=gene-NBT03_gp149;Dbxref=GenBank:YP_010377151.1,GeneID:72551565;Name=OPG173;Note=Old product: MPXVgp154%3B Hypothetical protein%3B similar to VACV-WR A44R and VACV-Cop A43.5R;gbkey=CDS;gene=OPG173;locus_tag=NBT03_gp149;product=MPXVgp154;protein_id=YP_010377151.1 +NC_063383.1 RefSeq gene 148355 149395 . - . ID=gene-NBT03_gp150;Dbxref=GeneID:72551566;Name=OPG174;gbkey=Gene;gene=OPG174;gene_biotype=protein_coding;locus_tag=NBT03_gp150;old_locus_tag=MPXV-M5312_HM12_Rivers-155 +NC_063383.1 RefSeq CDS 148355 149395 . - 0 ID=cds-YP_010377152.1;Parent=gene-NBT03_gp150;Dbxref=GenBank:YP_010377152.1,GeneID:72551566;Name=OPG174;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp155%3B 3-b-Hydroxy-delta5-steroid dehydrogenase%3B 3 beta-hydroxysteroid dehydrogenase/delta 5->4 isomerase%3B similar to VACV-WR A45L and VACV-Cop A44L;gbkey=CDS;gene=OPG174;locus_tag=NBT03_gp150;product=Hydroxysteroid dehydrogenase;protein_id=YP_010377152.1 +NC_063383.1 RefSeq gene 149442 149819 . + . ID=gene-NBT03_gp151;Dbxref=GeneID:72551567;Name=OPG175;gbkey=Gene;gene=OPG175;gene_biotype=protein_coding;locus_tag=NBT03_gp151;old_locus_tag=MPXV-M5312_HM12_Rivers-156 +NC_063383.1 RefSeq CDS 149442 149819 . + 0 ID=cds-YP_010377153.1;Parent=gene-NBT03_gp151;Dbxref=GenBank:YP_010377153.1,GeneID:72551567;Name=OPG175;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp156%3B virion core protein%3B Inactive Cu-Zn superoxide dismutase-like virion protein%3B similar to VACV-WR A46R and VACV-Cop A45R;gbkey=CDS;gene=OPG175;locus_tag=NBT03_gp151;product=Copper/zinc superoxide dismutase;protein_id=YP_010377153.1 +NC_063383.1 RefSeq gene 149809 150531 . + . ID=gene-NBT03_gp152;Dbxref=GeneID:72551568;Name=OPG176;gbkey=Gene;gene=OPG176;gene_biotype=protein_coding;locus_tag=NBT03_gp152;old_locus_tag=MPXV-M5312_HM12_Rivers-157 +NC_063383.1 RefSeq CDS 149809 150531 . + 0 ID=cds-YP_010377154.1;Parent=gene-NBT03_gp152;Dbxref=GenBank:YP_010377154.1,GeneID:72551568;Name=OPG176;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp157%3B IL-1/TLR signaling inhibitor%3B similar to VACV-WR A47R and VACV-Cop A46R;gbkey=CDS;gene=OPG176;locus_tag=NBT03_gp152;product=Bcl-2-like protein;protein_id=YP_010377154.1 +NC_063383.1 RefSeq sequence_feature 150684 151407 . - . ID=id-NC_063383.1:150684..151407;exon_number=OPG177;gbkey=misc_feature;number=OPG177 +NC_063383.1 RefSeq gene 151509 152123 . + . ID=gene-NBT03_gp153;Dbxref=GeneID:72551569;Name=OPG178;gbkey=Gene;gene=OPG178;gene_biotype=protein_coding;locus_tag=NBT03_gp153;old_locus_tag=MPXV-M5312_HM12_Rivers-158 +NC_063383.1 RefSeq CDS 151509 152123 . + 0 ID=cds-YP_010377155.1;Parent=gene-NBT03_gp153;Dbxref=GenBank:YP_010377155.1,GeneID:72551569;Name=OPG178;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp159%3B thymidylate kinase%3B start of ORF is missing approx. 37 AA compared to CPXVs%3B similar to VACV-WR A49R and VACV-Cop A48R;gbkey=CDS;gene=OPG178;locus_tag=NBT03_gp153;product=Thymidylate kinase;protein_id=YP_010377155.1 +NC_063383.1 RefSeq sequence_feature 152172 152660 . + . ID=id-NC_063383.1:152172..152660;exon_number=OPG179;gbkey=misc_feature;number=OPG179 +NC_063383.1 RefSeq gene 152692 154371 . + . ID=gene-NBT03_gp154;Dbxref=GeneID:72551570;Name=OPG180;gbkey=Gene;gene=OPG180;gene_biotype=protein_coding;locus_tag=NBT03_gp154;old_locus_tag=MPXV-M5312_HM12_Rivers-159 +NC_063383.1 RefSeq CDS 152692 154371 . + 0 ID=cds-YP_010377156.1;Parent=gene-NBT03_gp154;Dbxref=GenBank:YP_010377156.1,GeneID:72551570;Name=OPG180;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp160%3B ATP-dependent DNA ligase%3B similar to VACV-WR A50R and VACV-Cop A50R;gbkey=CDS;gene=OPG180;locus_tag=NBT03_gp154;product=DNA ligase (2);protein_id=YP_010377156.1 +NC_063383.1 RefSeq gene 154412 155416 . + . ID=gene-NBT03_gp155;Dbxref=GeneID:72551571;Name=OPG181;gbkey=Gene;gene=OPG181;gene_biotype=protein_coding;locus_tag=NBT03_gp155;old_locus_tag=MPXV-M5312_HM12_Rivers-160 +NC_063383.1 RefSeq CDS 154412 155416 . + 0 ID=cds-YP_010377157.1;Parent=gene-NBT03_gp155;Dbxref=GenBank:YP_010377157.1,GeneID:72551571;Name=OPG181;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp161%3B Hypothetical protein%3B similar to VACV-WR A51R and VACV-Cop A51R;gbkey=CDS;gene=OPG181;locus_tag=NBT03_gp155;product=M137R;protein_id=YP_010377157.1 +NC_063383.1 RefSeq sequence_feature 155485 156037 . + . ID=id-NC_063383.1:155485..156037;exon_number=OPG182;gbkey=misc_feature;number=OPG182 +NC_063383.1 RefSeq sequence_feature 156355 156916 . + . ID=id-NC_063383.1:156355..156916;exon_number=OPG183;gbkey=misc_feature;number=OPG183 +NC_063383.1 RefSeq sequence_feature 157176 158867 . + . ID=id-NC_063383.1:157176..158867;exon_number=OPG184;gbkey=misc_feature;number=OPG184 +NC_063383.1 RefSeq gene 158917 159858 . + . ID=gene-NBT03_gp156;Dbxref=GeneID:72551572;Name=OPG185;gbkey=Gene;gene=OPG185;gene_biotype=protein_coding;locus_tag=NBT03_gp156;old_locus_tag=MPXV-M5312_HM12_Rivers-162 +NC_063383.1 RefSeq CDS 158917 159858 . + 0 ID=cds-YP_010377158.1;Parent=gene-NBT03_gp156;Dbxref=GenBank:YP_010377158.1,GeneID:72551572;Name=OPG185;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp163%3B EEV envelope and cell membrane glycoprotein hemagglutinin%3B inhibition of the ability of infected cells to fuse%3B interacts with VAC F13L%3B similar to VACV-WR B2R and VACV-Cop A56R;gbkey=CDS;gene=OPG185;locus_tag=NBT03_gp156;product=Hemagglutinin;protein_id=YP_010377158.1 +NC_063383.1 RefSeq sequence_feature 159876 160470 . + . ID=id-NC_063383.1:159876..160470;exon_number=OPG186;gbkey=misc_feature;number=OPG186 +NC_063383.1 RefSeq gene 160622 161533 . + . ID=gene-NBT03_gp157;Dbxref=GeneID:72551573;Name=OPG187;gbkey=Gene;gene=OPG187;gene_biotype=protein_coding;locus_tag=NBT03_gp157;old_locus_tag=MPXV-M5312_HM12_Rivers-163 +NC_063383.1 RefSeq CDS 160622 161533 . + 0 ID=cds-YP_010377159.1;Parent=gene-NBT03_gp157;Dbxref=GenBank:YP_010377159.1,GeneID:72551573;Name=OPG187;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp164%3B serine%3B Ser/Thr Kinase%3B similar to VACV-WR B3R and VACV-Cop B1R;gbkey=CDS;gene=OPG187;locus_tag=NBT03_gp157;product=Ser/thr kinase;protein_id=YP_010377159.1 +NC_063383.1 RefSeq gene 161596 163107 . + . ID=gene-NBT03_gp158;Dbxref=GeneID:72551574;Name=OPG188;gbkey=Gene;gene=OPG188;gene_biotype=protein_coding;locus_tag=NBT03_gp158;old_locus_tag=MPXV-M5312_HM12_Rivers-164 +NC_063383.1 RefSeq CDS 161596 163107 . + 0 ID=cds-YP_010377160.1;Parent=gene-NBT03_gp158;Dbxref=GenBank:YP_010377160.1,GeneID:72551574;Name=OPG188;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp165%3B schlafen-like%3B similar to VACV-WR B4R and VACV-Cop B2R;gbkey=CDS;gene=OPG188;locus_tag=NBT03_gp158;product=Schlafen (1);protein_id=YP_010377160.1 +NC_063383.1 RefSeq gene 163333 165018 . + . ID=gene-NBT03_gp159;Dbxref=GeneID:72551575;Name=OPG189;gbkey=Gene;gene=OPG189;gene_biotype=protein_coding;locus_tag=NBT03_gp159;old_locus_tag=MPXV-M5312_HM12_Rivers-165 +NC_063383.1 RefSeq CDS 163333 165018 . + 0 ID=cds-YP_010377161.1;Parent=gene-NBT03_gp159;Dbxref=GenBank:YP_010377161.1,GeneID:72551575;Name=OPG189;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp166%3B ankyrin-like%3B similar to VACV-WR B5R and VACV-Cop B4R;gbkey=CDS;gene=OPG189;locus_tag=NBT03_gp159;product=Ankyrin repeat protein (25);protein_id=YP_010377161.1 +NC_063383.1 RefSeq gene 165122 166075 . + . ID=gene-NBT03_gp160;Dbxref=GeneID:72551576;Name=OPG190;gbkey=Gene;gene=OPG190;gene_biotype=protein_coding;locus_tag=NBT03_gp160;old_locus_tag=MPXV-M5312_HM12_Rivers-166 +NC_063383.1 RefSeq CDS 165122 166075 . + 0 ID=cds-YP_010377162.1;Parent=gene-NBT03_gp160;Dbxref=GenBank:YP_010377162.1,GeneID:72551576;Name=OPG190;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp167%3B palmitated 42 kDa glycoprotein located both on the membranes of infected cells and on EEV envelope%3B complement control protein-like%3B EEV type-1 membrane glycoprotein%2C protective antigen%3B similar to VACV-WR B6R and VACV-Cop B5R;gbkey=CDS;gene=OPG190;locus_tag=NBT03_gp160;product=EEV type-I membrane glycoprotein;protein_id=YP_010377162.1 +NC_063383.1 RefSeq gene 166161 166667 . + . ID=gene-NBT03_gp161;Dbxref=GeneID:72551577;Name=OPG191;gbkey=Gene;gene=OPG191;gene_biotype=protein_coding;locus_tag=NBT03_gp161;old_locus_tag=MPXV-M5312_HM12_Rivers-167 +NC_063383.1 RefSeq CDS 166161 166667 . + 0 ID=cds-YP_010377163.1;Parent=gene-NBT03_gp161;Dbxref=GenBank:YP_010377163.1,GeneID:72551577;Name=OPG191;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp168%3B Ankyrin-like protein%3B similar to VACV-WR B7R and VACV-Cop B6R;gbkey=CDS;gene=OPG191;locus_tag=NBT03_gp161;product=Ankyrin-like protein (46);protein_id=YP_010377163.1 +NC_063383.1 RefSeq gene 166731 167279 . + . ID=gene-NBT03_gp162;Dbxref=GeneID:72551578;Name=OPG192;gbkey=Gene;gene=OPG192;gene_biotype=protein_coding;locus_tag=NBT03_gp162;old_locus_tag=MPXV-M5312_HM12_Rivers-168 +NC_063383.1 RefSeq CDS 166731 167279 . + 0 ID=cds-YP_010377164.1;Parent=gene-NBT03_gp162;Dbxref=GenBank:YP_010377164.1,GeneID:72551578;Name=OPG192;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp169%3B Virulence%2C ER resident%3B similar to VACV-WR B8R and VACV-Cop B7R;gbkey=CDS;gene=OPG192;locus_tag=NBT03_gp162;product=Virulence protein;protein_id=YP_010377164.1 +NC_063383.1 RefSeq gene 167334 168137 . + . ID=gene-NBT03_gp163;Dbxref=GeneID:72551579;Name=OPG193;gbkey=Gene;gene=OPG193;gene_biotype=protein_coding;locus_tag=NBT03_gp163;old_locus_tag=MPXV-M5312_HM12_Rivers-169 +NC_063383.1 RefSeq CDS 167334 168137 . + 0 ID=cds-YP_010377165.1;Parent=gene-NBT03_gp163;Dbxref=GenBank:YP_010377165.1,GeneID:72551579;Name=OPG193;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp170%3B secreted IFN-g binding protein%3B Soluble IFN-g receptor-like protein%3B similar to VACV-WR B9R and VACV-Cop B8R;gbkey=CDS;gene=OPG193;locus_tag=NBT03_gp163;product=Soluble interferon-gamma receptor-like protein;protein_id=YP_010377165.1 +NC_063383.1 RefSeq gene 168230 168895 . + . ID=gene-NBT03_gp164;Dbxref=GeneID:72551580;Name=OPG195;gbkey=Gene;gene=OPG195;gene_biotype=protein_coding;locus_tag=NBT03_gp164;old_locus_tag=MPXV-M5312_HM12_Rivers-170 +NC_063383.1 RefSeq CDS 168230 168895 . + 0 ID=cds-YP_010377166.1;Parent=gene-NBT03_gp164;Dbxref=GenBank:YP_010377166.1,GeneID:72551580;Name=OPG195;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp171%3B shope fibroma virus T4 protein-like%3B ER-localized apoptosis regulator%3B similar to VACV-WR B10R and VACV-Cop B9R;gbkey=CDS;gene=OPG195;locus_tag=NBT03_gp164;product=Intracellular viral protein;protein_id=YP_010377166.1 +NC_063383.1 RefSeq sequence_feature 169001 169642 . + . ID=id-NC_063383.1:169001..169642;exon_number=OPG196;gbkey=misc_feature;number=OPG196 +NC_063383.1 RefSeq gene 169670 169972 . + . ID=gene-NBT03_gp165;Dbxref=GeneID:72551581;Name=OPG197;gbkey=Gene;gene=OPG197;gene_biotype=protein_coding;locus_tag=NBT03_gp165;old_locus_tag=MPXV-M5312_HM12_Rivers-171 +NC_063383.1 RefSeq CDS 169670 169972 . + 0 ID=cds-YP_010377167.1;Parent=gene-NBT03_gp165;Dbxref=GenBank:YP_010377167.1,GeneID:72551581;Name=OPG197;Note=Taxonomic breadth: chordopoxvirinae%3B Hypothetical protein%3B similar to VACV-Cop-B11R;gbkey=CDS;gene=OPG197;locus_tag=NBT03_gp165;product=CPXV205 protein;protein_id=YP_010377167.1 +NC_063383.1 RefSeq gene 170038 170886 . + . ID=gene-NBT03_gp166;Dbxref=GeneID:72551582;Name=OPG198;gbkey=Gene;gene=OPG198;gene_biotype=protein_coding;locus_tag=NBT03_gp166;old_locus_tag=MPXV-M5312_HM12_Rivers-172 +NC_063383.1 RefSeq CDS 170038 170886 . + 0 ID=cds-YP_010377168.1;Parent=gene-NBT03_gp166;Dbxref=GenBank:YP_010377168.1,GeneID:72551582;Name=OPG198;Note=Taxonomic breadth: poxviridae%3B protein kinase-like%3B similar to VACV-WR B11R and VACV-Cop B12R;gbkey=CDS;gene=OPG198;locus_tag=NBT03_gp166;product=Ser/thr kinase;protein_id=YP_010377168.1 +NC_063383.1 RefSeq gene 170988 172022 . + . ID=gene-NBT03_gp167;Dbxref=GeneID:72551583;Name=OPG199;gbkey=Gene;gene=OPG199;gene_biotype=protein_coding;locus_tag=NBT03_gp167;old_locus_tag=MPXV-M5312_HM12_Rivers-173 +NC_063383.1 RefSeq CDS 170988 172022 . + 0 ID=cds-YP_010377169.1;Parent=gene-NBT03_gp167;Dbxref=GenBank:YP_010377169.1,GeneID:72551583;Name=OPG199;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp173%3B serine protease inhibitor-like%2C SPI-2%3B inhibition of the IL-1b converting enzyme%3B apoptosis inhibition%3B Serpin 1%2C2%2C3%3B similar to VACV-WR B12R and VACV-Cop K2L;gbkey=CDS;gene=OPG199;locus_tag=NBT03_gp167;product=Serpin;protein_id=YP_010377169.1 +NC_063383.1 RefSeq gene 172150 172599 . + . ID=gene-NBT03_gp168;Dbxref=GeneID:72551584;Name=OPG200;gbkey=Gene;gene=OPG200;gene_biotype=protein_coding;locus_tag=NBT03_gp168;old_locus_tag=MPXV-M5312_HM12_Rivers-174 +NC_063383.1 RefSeq CDS 172150 172599 . + 0 ID=cds-YP_010377170.1;Parent=gene-NBT03_gp168;Dbxref=GenBank:YP_010377170.1,GeneID:72551584;Name=OPG200;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp174%3B Hypothetical protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR B13R and VACV-Cop C16L and B15R;gbkey=CDS;gene=OPG200;locus_tag=NBT03_gp168;product=Bcl-2-like protein;protein_id=YP_010377170.1 +NC_063383.1 RefSeq sequence_feature 172685 173697 . + . ID=id-NC_063383.1:172685..173697;exon_number=OPG201;gbkey=misc_feature;number=OPG201 +NC_063383.1 RefSeq sequence_feature 173744 174187 . - . ID=id-NC_063383.1:173744..174187;exon_number=OPG202;gbkey=misc_feature;number=OPG202 +NC_063383.1 RefSeq sequence_feature 174328 174456 . + . ID=id-NC_063383.1:174328..174456;exon_number=OPG203;gbkey=misc_feature;number=OPG203 +NC_063383.1 RefSeq gene 174532 175587 . + . ID=gene-NBT03_gp169;Dbxref=GeneID:72551585;Name=OPG204;gbkey=Gene;gene=OPG204;gene_biotype=protein_coding;locus_tag=NBT03_gp169;old_locus_tag=MPXV-M5312_HM12_Rivers-177 +NC_063383.1 RefSeq CDS 174532 175587 . + 0 ID=cds-YP_010377172.1;Parent=gene-NBT03_gp169;Dbxref=GenBank:YP_010377172.1,GeneID:72551585;Name=OPG204;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp177%3B cell surface antigen and secreted IFN-a%3B IFN-alpha/beta receptor glycoprotein%3B similar to VACV-WR B16R and VACV-Cop B19R;gbkey=CDS;gene=OPG204;locus_tag=NBT03_gp169;product=IFN-alpha/beta-receptor-like secreted glycoprotein;protein_id=YP_010377172.1 +NC_063383.1 RefSeq gene 175656 178019 . + . ID=gene-NBT03_gp170;Dbxref=GeneID:72551586;Name=OPG205;gbkey=Gene;gene=OPG205;gene_biotype=protein_coding;locus_tag=NBT03_gp170;old_locus_tag=MPXV-M5312_HM12_Rivers-178 +NC_063383.1 RefSeq CDS 175656 178019 . + 0 ID=cds-YP_010377173.1;Parent=gene-NBT03_gp170;Dbxref=GenBank:YP_010377173.1,GeneID:72551586;Name=OPG205;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp178%3B ankyrin-like%3B similar to VACV-WR B17R and VACV-Cop B20R;gbkey=CDS;gene=OPG205;locus_tag=NBT03_gp170;product=Ankyrin repeat protein (44);protein_id=YP_010377173.1 +NC_063383.1 RefSeq sequence_feature 178118 178916 . + . ID=id-NC_063383.1:178118..178916;exon_number=OPG206;gbkey=misc_feature;number=OPG206 +NC_063383.1 RefSeq gene 179266 180339 . + . ID=gene-NBT03_gp171;Dbxref=GeneID:72551587;Name=OPG208;gbkey=Gene;gene=OPG208;gene_biotype=protein_coding;locus_tag=NBT03_gp171;old_locus_tag=MPXV-M5312_HM12_Rivers-180 +NC_063383.1 RefSeq CDS 179266 180339 . + 0 ID=cds-YP_010377174.1;Parent=gene-NBT03_gp171;Dbxref=GenBank:YP_010377174.1,GeneID:72551587;Name=OPG208;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp180%3B serine protease inhibitor-like%2C SPI-1%3B apoptosis inhibition%3B Serpin 1%2C2%2C3%3B Actual start may be at position 179%2C074%3B annotated start of ORF is missing approx. 17 AA compared to CPXVs%3B similar to VACV-WR B19R and VACV-Cop K2L;gbkey=CDS;gene=OPG208;locus_tag=NBT03_gp171;product=Serpin;protein_id=YP_010377174.1 +NC_063383.1 RefSeq gene 180518 181090 . + . ID=gene-NBT03_gp172;Dbxref=GeneID:72551588;Name=OPG209;gbkey=Gene;gene=OPG209;gene_biotype=protein_coding;locus_tag=NBT03_gp172;old_locus_tag=MPXV-M5312_HM12_Rivers-181 +NC_063383.1 RefSeq CDS 180518 181090 . + 0 ID=cds-YP_010377175.1;Parent=gene-NBT03_gp172;Dbxref=GenBank:YP_010377175.1,GeneID:72551588;Name=OPG209;Note=Old product: MPXVgp181%3B Hypothetical protein%3B similar to VACV-WR B20R and VACV-Cop C14L;gbkey=CDS;gene=OPG209;locus_tag=NBT03_gp172;product=Virulence protein;protein_id=YP_010377175.1 +NC_063383.1 RefSeq gene 181356 186998 . + . ID=gene-NBT03_gp173;Dbxref=GeneID:72551589;Name=OPG210;gbkey=Gene;gene=OPG210;gene_biotype=protein_coding;locus_tag=NBT03_gp173;old_locus_tag=MPXV-M5312_HM12_Rivers-182 +NC_063383.1 RefSeq CDS 181356 186998 . + 0 ID=cds-YP_010377176.1;Parent=gene-NBT03_gp173;Dbxref=GenBank:YP_010377176.1,GeneID:72551589;Name=OPG210;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp182%3B Surface glycoprotein%3B putative membrane-associated glycoprotein%3B cadherin-like domain%3B similar to VACV-WR B21R;gbkey=CDS;gene=OPG210;locus_tag=NBT03_gp173;product=B22R family protein;protein_id=YP_010377176.1 +NC_063383.1 RefSeq sequence_feature 187317 187743 . + . ID=id-NC_063383.1:187317..187743;exon_number=OPG212;gbkey=misc_feature;number=OPG212 +NC_063383.1 RefSeq sequence_feature 187822 188298 . + . ID=id-NC_063383.1:187822..188298;exon_number=OPG213;gbkey=misc_feature;number=OPG213 +NC_063383.1 RefSeq sequence_feature 188458 188963 . + . ID=id-NC_063383.1:188458..188963;exon_number=OPG214;gbkey=misc_feature;number=OPG214 +NC_063383.1 RefSeq gene 189199 189660 . + . ID=gene-NBT03_gp174;Dbxref=GeneID:72551590;Name=OPG005;gbkey=Gene;gene=OPG005;gene_biotype=protein_coding;locus_tag=NBT03_gp174;old_locus_tag=MPXV-M5312_HM12_Rivers-184 +NC_063383.1 RefSeq CDS 189199 189660 . + 0 ID=cds-YP_010377177.1;Parent=gene-NBT03_gp174;Dbxref=GenBank:YP_010377177.1,GeneID:72551590;Name=OPG005;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp185%3B VAC B15R-like%3B Hypothetical protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR N1R and VACV-Cop C16L and B22R;gbkey=CDS;gene=OPG005;locus_tag=NBT03_gp174;product=Bcl-2-like protein;protein_id=YP_010377177.1 +NC_063383.1 RefSeq gene 190410 190940 . + . ID=gene-NBT03_gp175;Dbxref=GeneID:72551591;Name=OPG016;gbkey=Gene;gene=OPG016;gene_biotype=protein_coding;locus_tag=NBT03_gp175;old_locus_tag=MPXV-M5312_HM12_Rivers-186 +NC_063383.1 RefSeq CDS 190410 190940 . + 0 ID=cds-YP_010377184.1;Parent=gene-NBT03_gp175;Dbxref=GenBank:YP_010377184.1,GeneID:72551591;Name=OPG016;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp187%3B similar to VACV-WR N3R;gbkey=CDS;gene=OPG016;locus_tag=NBT03_gp175;product=Brix domain protein;protein_id=YP_010377184.1 +NC_063383.1 RefSeq long_terminal_repeat 190788 197209 . + . ID=id-NC_063383.1:190788..197209;gbkey=repeat_region;rpt_type=long_terminal_repeat +NC_063383.1 RefSeq gene 191054 192367 . + . ID=gene-NBT03_gp176;Dbxref=GeneID:72551592;Name=OPG015_dup;gbkey=Gene;gene=OPG015_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp176;old_locus_tag=MPXV-M5312_HM12_Rivers-187 +NC_063383.1 RefSeq CDS 191054 192367 . + 0 ID=cds-YP_010377179.1;Parent=gene-NBT03_gp176;Dbxref=GenBank:YP_010377179.1,GeneID:72551592;Name=OPG015_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp188%3B ankyrin-like%3B Ankyrin (CPXV-017)%3B similar to VACV-WR N4R;gbkey=CDS;gene=OPG015_dup;locus_tag=NBT03_gp176;product=Ankyrin repeat protein (39);protein_id=YP_010377179.1 +NC_063383.1 RefSeq gene 192603 194369 . + . ID=gene-NBT03_gp177;Dbxref=GeneID:72551593;Name=OPG003_dup;gbkey=Gene;gene=OPG003_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp177;old_locus_tag=MPXV-M5312_HM12_Rivers-188 +NC_063383.1 RefSeq CDS 192603 194369 . + 0 ID=cds-YP_010377180.1;Parent=gene-NBT03_gp177;Dbxref=GenBank:YP_010377180.1,GeneID:72551593;Name=OPG003_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp189%3B ankyrin-like%3B similar to VACV-WR J1R and VACV-Cop C19L;gbkey=CDS;gene=OPG003_dup;locus_tag=NBT03_gp177;product=Ankyrin repeat protein (25);protein_id=YP_010377180.1 +NC_063383.1 RefSeq gene 194459 195508 . + . ID=gene-NBT03_gp178;Dbxref=GeneID:72551594;Name=OPG002_dup;gbkey=Gene;gene=OPG002_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp178;old_locus_tag=MPXV-M5312_HM12_Rivers-189 +NC_063383.1 RefSeq CDS 194459 195508 . + 0 ID=cds-YP_010377181.1;Parent=gene-NBT03_gp178;Dbxref=GenBank:YP_010377181.1,GeneID:72551594;Name=OPG002_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp190%3B secreted TNF binding protein%3B TNF receptor (CrmB)%3B similar to VACV-WR J2R and VACV-Cop C22L;gbkey=CDS;gene=OPG002_dup;locus_tag=NBT03_gp178;product=Crm-B secreted TNF-alpha-receptor-like protein;protein_id=YP_010377181.1 +NC_063383.1 RefSeq gene 195635 196375 . + . ID=gene-NBT03_gp179;Dbxref=GeneID:72551595;Name=OPG001_dup;gbkey=Gene;gene=OPG001_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp179;old_locus_tag=MPXV-M5312_HM12_Rivers-190 +NC_063383.1 RefSeq CDS 195635 196375 . + 0 ID=cds-YP_010377182.1;Parent=gene-NBT03_gp179;Dbxref=GenBank:YP_010377182.1,GeneID:72551595;Name=OPG001_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp191%3B Chemokine binding protein (Cop-C23L)%3B most abundant secreted protein%3B CC-chemokine binding protein%3B similar to VACV-WR J3R and VACV-Cop C23L and B29R;gbkey=CDS;gene=OPG001_dup;locus_tag=NBT03_gp179;product=Chemokine binding protein;protein_id=YP_010377182.1 diff --git a/data/nextstrain/mpx/mpxv/ancestral/pathogen.json b/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/pathogen.json similarity index 83% rename from data/nextstrain/mpx/mpxv/ancestral/pathogen.json rename to data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/pathogen.json index 03886197..0ce33154 100644 --- a/data/nextstrain/mpx/mpxv/ancestral/pathogen.json +++ b/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/pathogen.json @@ -7,10 +7,23 @@ "minSeedCover": 0.1, "gapAlignmentSide": "left" }, + "attributes": { + "name": { + "value": "MPXV", + "valueFriendly": "Monkeypox (All Clades)" + }, + "reference": { + "value": "ancestral", + "valueFriendly": "Reconstructed ancestral MPXV" + } + }, "compatibility": { "cli": "3.0.0-alpha.0", "web": "3.0.0-alpha.0" }, + "deprecated": false, + "enabled": true, + "experimental": false, "files": { "changelog": "CHANGELOG.md", "examples": "sequences.fasta", @@ -20,6 +33,7 @@ "reference": "reference.fasta", "treeJson": "tree.json" }, + "official": true, "qc": { "frameShifts": { "enabled": true, @@ -192,34 +206,5 @@ "schemaVersion": "3.0.0", "version": { "tag": "unreleased" - }, - "attributes": { - "name": "Monkeypox (All Clades)", - "reference name": "Reconstructed ancestral MPXV", - "reference accession": "ancestral" - }, - "maintenance": { - "website": [ - "https://nextstrain.org", - "https://clades.nextstrain.org" - ], - "documentation": [ - "https://github.com/nextstrain/nextclade_data", - "https://docs.nextstrain.org/projects/nextclade" - ], - "source code": [ - "https://github.com/nextstrain/nextclade_data", - "https://github.com/neherlab/nextclade_data_workflows" - ], - "issues": [ - "https://github.com/nextstrain/nextclade_data", - "https://github.com/nextstrain/nextclade_data/issues" - ], - "organizations": [ - "Nextstrain" - ], - "authors": [ - "Nextstrain team " - ] } } diff --git a/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/reference.fasta b/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/reference.fasta new file mode 100644 index 00000000..7476b515 --- /dev/null +++ b/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/reference.fasta @@ -0,0 +1,2 @@ +>reconstructed_ancestral_mpox +ATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGCATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACAAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAACATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCGCTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCTGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAGGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATGGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCCGTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACGGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGATCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGCGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATAGGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATGATGTCATTAACGACATCCGCCTTGTATATGATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATAACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGAGAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAAATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAGTCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTGCCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCTACTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGTCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATGTGTTTGTGTAGTTCTGCCCTATCATCTACATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAACGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGCATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATAGGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATGCGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCTTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATACATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTAGAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATCGATGTCAACACATTCTACATTTTTTTAATCGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAAGAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACGACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTATTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATATTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACCCGTTTTAGAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCATCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTCTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGCTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGGCAAATGTTTATAGTACTAAGAATTGGGCAAGCATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTGCGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGAGATGATATACAGATGCAATACGGTACCGCAATTTCGTGGTTGATAATCATCATACGCGTATCCGTACTCGTCATCCTCATAAAGAACACTGCAGCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTGTGTAATGGATTAGTGCCACTGTCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACCAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGAAGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACACTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTACTAGTGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTTTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAACGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTATACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTCGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACGAATACCGACGGTGTTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGAAATCAGTTAGGAAGAAAAAATTATCTATCATCATCATCATCTATTGGATAACGTCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATGGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGTTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATCTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACTTATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAGATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCCTCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATAATTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGCATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTACTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTCTCTTGAAGTACTATAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTCGACATTAATTCCTTTTTAAATTTCCGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGCGATAGAACCGCTAAAAAGCCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAGGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACATTCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGGTTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACGATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACGCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTATTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGAGGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAGAGTAAGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCGTTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGCACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATACATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTAGATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGCCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCGGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCTGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCGGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCTTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCCGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCACCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCCAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGCACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTCATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAATTGAATTGATGATATAGGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGTGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGTTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGCGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATCCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTTTGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGACGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTGCCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTATACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGATAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACATCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAACGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGCGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACACGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATACAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTCGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGCGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACCATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGCCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATTGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGGCCGGGCGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCCGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTGAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGACAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTATAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACGCATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAAATTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATCAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAAGCATGTCCAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGTGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCTGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGAATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTGCATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGCGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACTATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCGATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATGAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGAGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGGCAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTCGGAGCTGTACACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCGTCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATTTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTCTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGTGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAAGATAGTAAAAATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACCGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGAGGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACTGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCAGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACCGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAAGATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGCTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGACTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGACGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATGTATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCCAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACATAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATACAAATAAGAAGGTACGGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGACATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATCGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATGACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCCAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGCGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACCACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTGATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGCGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGTATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCGCTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATAGATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCCTCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAACACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTCAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGCTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCATAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCGTCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTACTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAGCATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAGTCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACGAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAACTCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCCTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGCATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTACAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCTGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTGCTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAGTTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCGCCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAACATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGCAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATGTTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGCGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGGCCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCGTCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTGCTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAACAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACGCATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATCGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTGCAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGTGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGAGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTGTTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAAACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGCATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTGTAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCTACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGGACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCTGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATTTACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATCGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATCACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTGTCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCGGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCCGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGTGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAGTGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCTGATAAGCTAACATCATACCCTCCTGTATATGTGAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCGCCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACACGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGTATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTGATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATGATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATACGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGAGAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATGTACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATACGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCGTTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACGCCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCGAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTACAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCGACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGTGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGATGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCCGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGCTGCTACGAGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTGCAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCATGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGAAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAAGATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAGAGATTATATGATTACTAGACGACAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAGTCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGCCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAACGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGCGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGAAGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCGAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCGATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGTCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGACATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCCGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGACCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGTACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCGGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTGTGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAGGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCACCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCGGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGCAGACAGCCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGTCGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGCCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCAATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATGCCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGCGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACTCATTTCGTTTATCATTATTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATACTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATGGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCCAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACAGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTTTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATCGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCGCCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCGATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACAAGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCGGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAACAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTAATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAACAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATACAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGACCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCAATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCGGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATGCAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCGAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTAGTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGCGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGCGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAGATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGAGTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTGGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCCATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGCGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATCTTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTCTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTACGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATGCCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTCTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGGCACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGGCGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGCAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTCCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGTCGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTGAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCACTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATGACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATGTTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTGGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCCGGTATCGGAGTGGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCCATCATATCATCATCTTCGATATTTATTTTGCTATCTTGATGATGTCCTGTATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATGTGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCGAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCGATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATACGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCGTTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGACGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTGTCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGACAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACAAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGCACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTAGACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCACATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGGCATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTCATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACGAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGCGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACCGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATGTCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGCGACGATTATCTTAATAAGCAACAAGATCATGAACACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTTGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGCGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAACTAATTTCACAGTAGATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATACTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATGATGTGGTAACGGGTGTTATTAATGGGGCTGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATCAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTTTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCGCACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGGGTCATAGAATTTATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGTCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCACGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAAGATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACACCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCTTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAAATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAATATTTATTCGGCATTGATGACACTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACCGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTCGTCTACATGTTCTGCCGTAACCGACAGGGAAACGGATGTATAATTTTTTTTATAGTGTGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGTATGTTTGACTTATGGTTAGACACGCATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTGCCCGATCCTCTCTTAAATGAATCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACGTCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACATTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTGTTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTGGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGTGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGTCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGATCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCGTCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTACTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGGTGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCGCTACTTGGTTAGTGTGTATTATTCAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCTCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACGATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGCCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCCTCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATGTACCGACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTGGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGGAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGGTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCGGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCGCGACTCCGGAACCAATTACTGATAATGTAGAAGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGACTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTTGTAGAAATATTTGGTATTACCACATTAATTATATTGTCGGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGCTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACGTGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATTAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGTAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGCGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAGTGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTGGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCTGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGGCAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCACGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATACGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTCGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTAAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGCGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCTCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATGCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGCGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACTGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAAGATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGCATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGCATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCCATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTCTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGTGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGAGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCGATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGCGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATGTAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGGTGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGCATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCGACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCGTTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCGAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGGAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTAAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAGCACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGGCACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATGCATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTGAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACGCAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGCAGAGTATCGTTGAGACTTCCCACAACGGACGCCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACTGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATGCATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATTGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTGCCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGCATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAATTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAAACATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATATGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGCGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAATGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTATAATATAAGCGACAGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTGGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGCTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGCAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGCTGCCGGATCTACGTATTTTAAAACAATGTTCACAACACCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATCTACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACGTATTAAAATGCACCGACTAAGAACGTAGAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAGGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCACTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATAACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAACGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCAAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGTGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCCTTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCTAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGACAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGCATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGGCAATCATGAATTTACAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTGCATGGTAATATAGGATTTTTGGAAATAAATAATTGTTACAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAACTATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACGCAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGGTGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTACAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCGCCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGGCCAAAAATTGAACCAGAATATGCGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGCAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACGCTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGACTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTACCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTGACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGCTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAACGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCGTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGGTACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTAAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGCAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATTACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACGCAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATCATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATACACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATCATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATCTGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGCACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATAAACATCCCCTGAATCTGTACCTACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCGCGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTAACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGGATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCGATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATCATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGAGGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACACAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATTAAAAAAGTTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCGCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGTAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGAAGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCGCCATGGAGTCGGCAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTACAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATTTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTCTCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTTATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTTATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATCATATACAAGGCGGATGTCGTTAATGACATCATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACCTATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGATCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCCGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAACGGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCCATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCCTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCAGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGCGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATGTTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATGCCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAAT diff --git a/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/sequences.fasta b/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/sequences.fasta new file mode 100644 index 00000000..2ba90ecf --- /dev/null +++ b/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/sequences.fasta @@ -0,0 +1,18 @@ +>MPXV_USA_2022_MA001 | ON563414.2 +TATTATATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCRAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTTGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGAGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGAGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATATAATA +>ON676708 +ATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATTATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGTTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTTTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGNNNNATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATNNNAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAAT +>ON674051 +TATTATATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATANTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTATAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATTAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTTGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATTAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATTACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTTCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACAAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATAAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTTATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAAACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTTGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTTAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTAATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTAAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAAAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGAACGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAAATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATTTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATAGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAAACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCNNNTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGCGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATTATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTTTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCAAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTTAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACAATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTTATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAATGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATTACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGAAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTTCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACACCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGANNATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTTGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTTATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAANTATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATATAATA +>MT903339 +CGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCAAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTTGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCAATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACAAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCG +>MPXV-UK_P2 | MT903344.1 +TAATTAATTTAATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAANNNNNNNNNNTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATTAAATTAATTA +>Yambuku_DRC_1985 +ATAATATTAATGTACTAAAACTTATGTATTATTAATTTATCTAACTAAAGTTAGTAAATTATATACATAATTTTATAATTAATTTAATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGACGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCATTGGCATAAGGATATTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTGTAAAACTTTTTTATGAGACAAGAGAGAAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAACATTTTTGTTTTGCAAACCGGAATATAGTACCCGGTACACTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTTGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTAACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCGCTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCTGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCGCCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAGGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATGGGTAAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCCGTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACGGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGATCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGCGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACATTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATAGGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTTGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATGATGTCATTAACGACATCCGCCTTGTATATGATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAAATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACACGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATAAAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGAGAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAAATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGTACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAGTCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTGCCGACTCCATGGCGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGTAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGTCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATGTATAATCATCACTGTCGCTATCATTATTGCGTTTGTGTAGTTCTGCCCTATCATCTACATCACTGTCACTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCATACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTGTGTGCAACGTTAGAAATTCTAAATCTATAGTATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAACGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATACACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGCATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATAGGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAATACTAAGTATGCGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTATAATCATCTTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTGATGGTTATTTACTAACAGACATTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATATATATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTAGAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATGGTTATTAGTTAAGGGACCCGATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATCGATGTCAACACATTCTACATTTTTTAATCGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACATTGCTTTATTATATTTTATAAGAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACAATCATACATCAATTAACTCATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACGACAAATACCGATCGGTAATTGTCTCTGTCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTATTTTTGGAATCATAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATATTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTTAGATAATTGTCCTATATGCCGTACCCGTTTTAGAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCATCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTCTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTATTTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGCTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGGCAAATGTTTATAGTACTAAGAATTGGGCAAGTATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACGCATTATTCCGTGCGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATAAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGAGATGATATACAGATGCAATACGGTACCGCAATTTCGTGGTTGATAATCATCATACGCGTATCCGTACTCGTCATCCTCATAAAGAACACTGCAGCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTAATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTGTGTAATGGATTAGTGCCACTGTCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATATCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACCAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGAAGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTCCAACCACTATTATATGATTATAGTTTCTATTTTTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACACTATATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTACTAGTGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTTTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAACGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATTTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGACGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTATACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAATTTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTCGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAATACGAATAAAAACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAATTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTATTATACAGATGTATTACAGCCTCATATATTACGTAATATAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAACGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACGAATACCGACGGTGTGTGTTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGAAATCAGTTAGGAAGAAAAAATTATCTATCATCATCTATTGGATAACGTCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATGGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGATTCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGTTACATATCTCTTCTATATTATTGTTGATATATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATCTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACTTATACTCATCATCTGTTTTAGGAATCCATGTATTATTACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGTACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAGATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCCTCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCATGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATAATTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCGGCTGCCATGTATTTCCTGGAGAGCAAGTAGATGATGAGGAACCAGATAGTTTATATCCATACTTGCACTTAAAGTCTACATTGTAGTTGTATGAGTGTATGATCTTTTAAGCCGCTAGAAGTTTTCCGTTTGATATAGGATGTGGACATTTAACAATCTGACACGTGGGTGGATTGGACCATTCTCCTCCTGAACACATGACACCAGAGTTACCAATCAACGAATATCCACTATTGCAACTATAAGTTACAATGCTCCCATCGATATAAAAATCCTCGTATCCGTTATGTCTTCCGTTGGATATAGATGGAGGTGATTGGCATTTAACAGATTCGCAAATAGGTGCCTCAGGATTCCATACCATAGATCCAGTAGATCCTAATTCACAATACGATTTAGATTCACCGATCAAATGATATCCGCTATTACAAGAGTACGTTATACTAGAGCCAAAGTCTACTCCGCCAATATCAAGTTGGCCATTATCGATATCTCGAGGCGATGGGCATCTCCGTTTAATACATTGATTAAAGAGTGTCCATCCGGTACCGGTACATTTAGCATATATGGGTCCCATTTTTTGCTTTCTGTATCCAGGTAGACATAGATATTCTATAGTGTCTCCTATGTTGTAATTAGCATCAGTCTCTACACTATTCTTAAATTTCATATTAATGGGGCGTGACGGAATAGTACAGTATGATAGAACACATCCTATTCCCAACAATGTCAGGAACGTCACGCTCTCCACCTTCATATTTATTTATCCGTAAAATGTTATCCTGGACATCGTACAAATAATAAAAAGCCCATATATATGTTCGCTATTGTAGAAATTGTTTTTCACAGTTGCTCAAAAACAATGGCAGTGACTTATGAGTTAGTTACACTTTGGAGTCTCATCTTTAGTAAACATATCATAATATTCGATATTACGAGTTGACATATCGAACAAATTCCAAGTATTTGATTTTGGATAATATTCGTATTTTGCATCTGCTATAATTAAGATATAATCACCACAAGAACACACGAACGTCTTTCCTACATGGTTAAAGTACATGTACAATTCTATCCATTTGTCTTCCTTAACTATATATTTGTATAGATAATTACGAGTCTCATGAGTAATTCCAGTAATTGCATAGATGTCACCATCGTATTCTACAGCATAAACTATACTATGACGTCTAGGCATGGGAGACTTTTTTATCCAACGATTTTTAGTGAAACATTCCACATCGTTTAATACTACATATTTCTCATAGTGGTATAAACTCCACCCATTACATATATATCATCGTTTACGAATACTGATGCGCCTGAATATCTAGGAGTGATTAAGTTTGGAAGTCTTTTCCATTTCGAAGTGCCGTGTTTCAAATATTCTGCTATACCCGTTGAAATAGAAAATTCTAATCCTCCTATTACATATAACTTTCCATCGTTAACACAAGTACTAACTTCTGATTTTAACGACACATATTAGTAACCGTTTTCCATTTTTTTTGTTTTAAGATCTACCCGCGATACGGAATAAACATGTCTATTGTTAATCATGCCGCCAATAATGTATAGACAATTATGTAAAACATTTGCATCATAGAATTGTCTATCTGTATTACCGACTATCGTCCAATATTCTGTTCTAGGAGAGTAATGGGTTATTGTGGATATATAATCAGAGTTTTTAATGACTACTATATTATGTTTTATACCATTTCGTGTCACAGCTTTGTAGATTTGGATATAGTTAATCCCAACAATGCTATAGCATTGCATATAGCATTAGTCATAAACTTGGGATGTAAAATGTTGATGATATCTACATCGTTTGGATTTTTATGTATCCACTTTAATAATATTATAGCGTAACATCCTCATGATTTACGTTAACGTTTTCGTGTGATAAGATAGTGGTCAGTTCATCCTTTGATAATTTTCCAAATTCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGCATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTACTACAGGCGGAACATCAATTATTATGGCAGCGACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAAATAATTTCCCCATTGATAGAAAATATCACGCGTTCCATTCTCTTGAAGTACTATAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTTATAAAAAAAATCATTTCGACATTAATTCCTTTTTAAATTTCCGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGCGATAGAACCGCTAAAAAGCCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAGGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACATTCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGGTTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACGATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTATACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACGCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTATTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGAGGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAATATGCGACAATAGTACGATGCAATGAGTAAGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACATAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCTAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCGTTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGCACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATACATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAATAAAATAATTATTCCTTACATCGTACCATAAACAATATATTAAGTAGATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGCCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCGGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCTGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCGGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAATTTATTGATGTCTACACATCCTTTTGTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCTTGTTAACAGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCCGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCACCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCCAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACTACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGCACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTCATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGCCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCGCTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAATTGAATTGATGATATAGGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGTGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGCCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGTTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGCGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATTCCATCCCATTCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTACTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTTTGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCTAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGACGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATTGTAGAATTGACTATTATATTGCCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTATACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGTAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGATAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCATCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACATCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAACGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGCGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACACGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATACAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTCGTACACATCTTGATGTGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGCGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACCATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGCCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATTGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGGCCGGGCGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCCGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCAGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTGAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGACAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATAACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTATAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACGCATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATCAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAATTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAAGCATGTCCAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGTGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATGCCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCTAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACGCTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCTGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGAATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTGCATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGCGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAATGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATATTAACTATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCGATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATGAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGAGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGGCAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATTATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTCGGAACTGTACACCATAGTACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCGTAGAAATTTTTTAGAGAGAACTAACACAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCCGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCGTCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATTTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTCTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTGAGACATTGAAACTAGGATATATAAAATTTAAGTGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAATGAGTAAAATCAAACACAAAATCTTCGTTCAAACTTAATCTTATTAGAATATTAGTGGAAGAAAGATTCTATAATAATGAATGCAGAGATTATAAATGGAGAATAATTGGAACACAAGTTGATAAAATATTGATAGCTAAATATACAATAGATGCAATGTATCGCATAAGACCGATATATATAATACAAAGCAGTACAGATACAATGATGATGTAGAAAATGGATTCATTGGATTGGATAAACTAAAATTAAACATTGTTCATGATATAGTTGAATCATGTATACCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGTATTGACTTTGTTAGTGAATATGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAAGATAGTAAAAATAATTATTAGAATAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTTATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACCGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGATCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGATGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGAGGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACTGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCATATATTAAAAAATAACACATTTTTGATAAATGGAAACTGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGGGATATAAATATTATGGCAGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACCGGTCCCGTTCCAATAGGTATCAAAGATATAGATTACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAAGATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGCTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGACTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGACGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATGTATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCCAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACATAATTACCTGTTGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACTGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCATATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATACAAATAAGAAGGTACGGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGACATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATCGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACACGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGTTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACAACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATGACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCCAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGCGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCGACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACCACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTGATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGCGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGTATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGCAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCGCTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGATGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGATCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCGGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATAGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATAGATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCCTCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATACAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTTGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAACACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTCAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGCTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCATAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCGTCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTACTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAGCATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAGTCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACGAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGCGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAACTCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCCTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGCATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATATAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTACAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGTCTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGGTAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCTGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGTTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGAAGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAATGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAAATGGTGTTCCAGCTCGTGTGTTCTACGTGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAATCCCATTGGATAGATTTTTTGAAGGATATCTTAATGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATTTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCATTCTCTTCTATTTTTAAGCCGGCTATATATTCTGCTATATTGTTGCTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAGTTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTTTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCGCCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAACATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGCAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATGTTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGCGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGGCCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCGTCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTGCTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAACAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACGCATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATCGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTGCAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGTGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGAGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTGTTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAAACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGCATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTGTAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCTACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGGACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCTGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGCGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATTTACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGTGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATCGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATCACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGCATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTGTCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCGGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAATTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACATATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCCGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGTGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAGTGGAGTAGTAAACGTGTACATGACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAATTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCTGATAAGCTAACATCATACCCTCCTGTATATGTGAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGATAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCGCCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACACGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGTAACAATTTTTTGTTTAATGCATGTATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTGATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACACTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACATACTTGATATCTAAGAAATCCTTAATGATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATACGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAGCAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGAGAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATGTACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGTTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATACGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCGTTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACGCCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCGAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTACAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCGACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGTGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGATGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATATTGGACATCAATACGCCGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAATGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTATTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCATTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGCTGCTACGAGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTGCAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCATGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCATTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAAACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGAAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACAGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAAGATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCGCATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAGAGATTATATGATTACTAGACGACAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAGTCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGCCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAACGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACATTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGCGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTCCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGTGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGAAGAATATCTCTAACGAGTGATCAAATTATTGATACATTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCGAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCGATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGTATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACAGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGTGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAGTGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTTGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGTCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGACATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATAGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCCGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACCGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGACCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCATCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGTACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCGGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAATAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTGTGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAGGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCACCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCATAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCGGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTATAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTGGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGCAGACAGCCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGTCGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGACCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTACTTCAACGAGGAAGGTTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTTACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCAATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGGAAAAATCAATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATGCCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGCAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGTGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCATTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGACAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGCGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACTCATTTCGTTTATCATTATTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACCAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATACTTAGAATTTTAGGACGGATCAATGAGTAAGATTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATGGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCCAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACAATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGTAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATTGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGTGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGATCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACAGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTTTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATCGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCGCCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCGATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACAAGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCGGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAACAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTAATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAATATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAACAGTGTTATTAATATTGCCAAGTTATCAGATCTAAAAAAAACTATCTATACAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGACCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCAATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCGGAAACATCAGGAATCTGAACCCGCTTCCGTGCCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATGCAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCGAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAACGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTAGTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGCGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTCGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGCGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAGATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGAGTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGTTTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTGATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTGGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCCATTGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGCGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACACACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATTATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATCTTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCACATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTCTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTACGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATGCCTTTTCATTCCTCGAGTCTATCGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTCTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGGCACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACACAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCAGCGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTACATTGATTTCATTATTACGTCCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGTGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGTCGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTATCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTGAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCACTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATGACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATGTTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGTGAGACCTGATTCAGAACTCAACTCATCATTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTGGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCAGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCCGGTATCGGAGTGGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCATCATCTTCGATATTTATTTTGCTATCTTGATGATGTCCTGTATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATGTGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATCGTATCGAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCGATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATACGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCGTTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGACGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGTGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTGTCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGACAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACCATGTTCATAGTCATTAAGTCATTAACAAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGCACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGATATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTAGACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCACATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGGCATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTCATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGACATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACGAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGCGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACGCTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTACATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACAACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGATAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGCACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACCGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATGTCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGCGACGATTATCTTAATAAGCAATAACAAGATCATGAACACGATGATATAGAATCATCGGTTGTATCATTGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACGATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTAATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTTGTCTGTATTCATTATTAGACGAGTCACTGACTATTTGGATAGACACATATGCGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAATAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAACTAATTTCACAGTAGATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACATGGAATAATGATGGTATCATTACATGCTGTATACTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATGATGTGGTAACGGGTGTTATTAATGGGGCTGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAATGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATCAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGGGCTATTGGGTATGAAAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACAATTACAATACATTTTTATCATAACACTACTTCGGTTAGATGTTTTAGAAAAAAATAAATATCACTACCGTTCTTGTTTTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCGCACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCAACTATACATTCTTCTGTTAATTTTACTAGATCATCATGGGTCATAGAATTTATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACAGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGTGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGTCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATTGTATATTTTATTTTATTTTATATTTTATATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGATGATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGTTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCATGTCTCATTAAAAATTTGGTAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCACGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAAGATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATATCACACCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCTTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAAATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAATATTTATTCGGCATTGATGACACTGGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACCGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATAATTCGTCTACATGTTCTGCCGTAACCGACAGGGAAACGGATGTATAATTTTTTTATAGTGTGATGGATATGATGGATATGATGGATATGATATATGATGGATATTATGATGGATATGATGGATATTATGATGGATATGATGGATATGATGGATATGATAAATATGATAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGTATGTTTGACTTATGGTTAGACACGCATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCATCAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATCGAATTCCCAATATCATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTGGCATGTGACTTTTCTCTAAAGGATGATGTTGCCCGATCCTCTCTTAAATGAATCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACGTCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATATTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATATGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACATTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTGTTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCAATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTTAATAGTTACATATAAACTGAAAAATAAAATAATACTATTTTAGTTGGTGGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATATGATAAAAATAGATGACGATGACAAGACTCCTACCGGTGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATATGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGTCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGATCAACATGAACATAAAGATAGATGATATGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGAATTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTTATAGATTATATAAAGGTACAAAAACAGGATATCGTCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTATGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATACTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGATGGTTTAAGTTTAAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTGGTCAGTGTATAATAAATTATATGTAGGAGGAGGAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGGTACCACATAATTATATAATGTATAAATGCGAACCGGTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCGGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCGCGACTCCGGAACCAATTACTGATAATGTAGAAGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGACTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTTGTAGAAATATTTGGTATTACCACATTAATTATATTGTCGGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGACGAGAAGGTGTTGATTACCATTACTTAACAGAGAGGCAATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGCTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGGCCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACGTGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATTAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCTGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGTAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGCGAGTGCAATAGAAACACGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAGTGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTGGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGCTATATACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTATATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCTGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGGCAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCACGACTACCTCAAACTGGTAGAGAGAGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGTTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATACGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAGGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTCATGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTAAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGCGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCTCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCTATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCTGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACAGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATGCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGCGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGAACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACTGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAAGATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGCATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAAACTGCATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTTTAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCCATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCACATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTCTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGTGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGAGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCGATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGTGACTTTCAAGATGATGCGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTATAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATGTAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGATGATGGTGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATATATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAACGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGCATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCGACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCGTTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCGAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGTAGTGTTACGGATATCTGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTTAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGGAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTACTAACAGGTTAACATTTTTTTTAAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAGCACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGGCACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGGGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACTTTTCCCAGAAACAAACTTTTTTTACCTACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATGCATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTGAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACGCAGATATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGTGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTACATGCAGAGTATCGTTGAGACTTCCCACAACGGACGCTGACGTCTTTTGGATAAGTAATGGTATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACTGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTATAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATGCATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATTGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTGCCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCTGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATAAGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGTTCTCTGTCATATTCATACACCTGCATAAACTTTCTATACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAATTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTCAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAAACATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATATGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGCGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAATGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAATAATTATTATAATATAAGCGACAGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTGGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGCTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTTGTGCAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCAATCTCAATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGCTGCCGGATCTACGTATTTTAAAACAATGTTCACAACACCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATCTACAGATGTTCGATAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACGTATTAAAATGCACCGACTAAGAACGTAGAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAGGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCACTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTTGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATAACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAACGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCAAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATATATCGTTATATATCGTTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGTAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGTGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCCTTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCTAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGACAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGGCGTTTATAGATGTTAATGAGGAGTATACAGAAGCATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAAAAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTGTATTCGTGACTTCATCCATCGCTAGTCCATTTTACATTCCCGTTATTCCACCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGCATGTTTAATATGAAAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGGTAATCATGAATTTACAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGATGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCGCCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGATACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTGCATGGTAATATAGGATTTTTGGAAATAAATAATTGTTACAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAACTATTATATTTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACGCAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGGTGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGCGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTACAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCGCCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGGCCAAAAATTGAACCAGAATATGCGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGCAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACGCTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGACTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCCGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTACCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTGACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGCTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAACGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCGTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGGTACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTATTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACATAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGATCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAAAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGCAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATTACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACGCAGTGCAAGATTAATCTAGAAATCAAATGTAATTATGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATCATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAATGTGTCTCATATTATAATACACAAGAATTAAAGTGTTGTAAACTATCTAAGCCAGGAACATATTCAGATCATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATCTGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGCACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTGTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATTCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATAAACATCCCCTGAATCTGTACCTACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCGCGTATCGTTATACAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATGTACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTAACCTTCGTCTACCTTCACAATGGCCTTTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGGATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAATGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCGATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACGTGAAGATGATATCATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGAGGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACACAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAGTTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCGCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGTAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGAAGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCGCCATGGAGTCGGCAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGACTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTACAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATTTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTCTCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTTATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGTGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATTTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATCATATACAAGGCGGATGTCGTTAATGACATCATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCAACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACCTATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAATGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACGCCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGATCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCCGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAACGGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTTACCCATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCCTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGCGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCAGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGCGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTTAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCAAACGATTCAGACACCGCACCACGAATTAAAAAAGTGTACCGGGTACTATATTCCGGTTTGCAAAACAAAAATGTTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTTCTCTCTTGTCTCATAAAAAAGTTTTACAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAATATCCTTATGCCAATGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCGTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATTAAATTAATTATAAAATTATGTATATAATTTACTAACTTTAGTTAGATAAATTAATAATACATAAGTTTTAGTACATTAATATTAT +>Ivory_Coast_2012 +CCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAATAGAATAAAAATATTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTAAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATGGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCCGTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTCTCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGATTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATAGGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATGATGTCATTAACGACATCCGCCTTGTATATGATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCAGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCGCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTTCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATAAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTACTTATAAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACGATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCAATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCAATTTCAGTATATTCTTCGCCGTTATAAAAGTAATGTTGTTTAATTGTAGGACGGTTGTTAGTATAATCACATGAATAATAATATTCTAATTCCTCGTATTGACTACTTACAGATACTCGAAATAGTCTGAAAAATTCTTCAAAGATATTTTTATAAAGATCTAGGAAAAGTTTATTACCGACCATGAACGAGATAGATGGATAAATATCCTTTCCATCAAAGGTCATAATTGGATAATTGTCCAGCAATATATCTGCTGTATTAGTTATATCACTTCCATTTATTTTCAGATTGAAGTAATGTACTAGTTTGTGACAATTAACAAGATACAAAAGAGATGCCGATACTAATACGTAAATAGCTATACGCGAATCCATTGTTACCTTTTTTTATTTCATAGGTCTATTAATAAATATATGTATTACTTAAGACTAGAAAAATCAAAAGTAAGTTTTTGATATTTGATTCTTACTTATTGTGGGATTGTAGTTTACTTAGTAATTCATCTCTGAATCCTGATAAATCATGCATATCAATGATGCAACTACGCAGCAAACTAGTAGGAATATAGATATCTGGATATGTACGTAAATAGTCGATTATATCTTTTACAATACTATTAGTCCCTATTGCGTTATCTATATATCCATTAATAATATTACACAGTGGATACTTATGAGAAATATACCTCTTACAGATTTTTAACGATATATACTAGAAAGATATGTGTGTAGTACTGTATTACCTAAATTATCAGTCTCATTCAAATATTGCATGACTATTATCGAGAATTGCTATATCCCTCTATACTCGATGCATTTATTACAGTAATTCAATCCAGCTAACATAAGAGCCAATCTCAATGTTGGTTTAATTATATCATCTTCATGTAATAATAACGATGGAAACTTTCCAGTAGCGTAACACTTATCTAAGAAGGATATAATAACTATGTCTACATTATGTCTCTTATCGAGAATATTCTTAACGAGATATCCATAGCTATTCTGGTGCTAATTATTCCTATATTATATTCCACGAAAAATGATGAAGGCCATTCATCATAAGATGATAAAAAGTGTAGTGAGTAAGAGTATTAGTGAGAGAGCATGAAGGAGATTTAGTATTTAGCAGTGAGGATATGATCCAAGAGGGTGAGATAGTCGTTCTCGTTCAGAATCTTTCGCAGCATAAGTAGTATGTCGATATACTTATCATTGAAGACTCTTCCGGTGACAATAGCTGATTGAGTACAAAGTCCAATTATTGCACAAAGTTCTTTGGCGGTTTTCATGGAGTCATTTCTGATGAAACATTTAATGATCTCCACGCAATTGTCGATATTGTCCCACGGAAGTGAATCCGAGAACTCCTTCAACTCGCTACCAAATAGCTCCATTGCATCAATTCTGAAAGAGATGAGAAGCCTGTAGAGAGGCCCTGCGCTTTCTCTATGGGTCCATCTATGAGAAACCCACAGGATGTATTCAGTCAGACAATGTCTGACATCAGTCACGGTATTCAGGGAGTCCTTAGTAGCGTGGCAATGACAGGGACTGAACTGGGCACAAGGAGAGGCCATTGTGAAGGTAGACGAAGGTAACCTGATGGTAGACCTGTAGCCGTCTGTGCTTAATAGAGGGCTTTAATTTCCATTTTTAATGGTGTCGTGAATGAGGAATGAGAGTGTCTCTCGTCCTTGGTTTACATGGATCAGAGTGAGAAAAAATATCTTGTATATTATTAACTAACAACCTTGGTTTCTATCCATGTTTAAAAAATGACCTATATGTTCTTTATTAATTCTATTTTAAACTTTATCCTCAAGACTCCTGACAAAATTAAAATCCAGAAAGCAGCAAACAATCCTGTTACAAGTTTACTGAAATCTCTCTTTGATTGTAGAGTATATGTAGTCAGAGCAAGAAACACTGCAGTAGTCAACATGAAAGCTTGCATAACGATACGTGCATCATAGAAAGTAACAACAGAGGCCAGCGTTAGAGATTCTAACAGTGTAAATCCACAAAGTATGTACAGATTCAGGGGATGTTCATGTCTGTGTAAAGTCAATGCGAAAATCAAGCCTATAGATCCGAACATTGATGCCAATATTAGAACAGGACTCCCTTGTATAAATGTCCGATGCATTCAAAGTATAAAAATACTGCAGCTGTTGCCGTTGTTAAAGGAAATTGTAGAAAGGATACCGTAGACTTTTCTTAGAAATGCCATTCGTATGTACACGCTGGCAGACGCCACCGAGCTGTCATAGTTGAAGTCGTCCTCGATAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATATATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATAGTATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGATACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACATGTTGTCTATTATCTGTTTATAGGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTCTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCTGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCTTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATACATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAATGTTTCCAAATATATTACTGGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACATACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATCGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATCATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATATTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAATTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACCCGTTTTAGAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCATCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATAGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACGCAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGCTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGGCAAATGTTTATAGTACTAAGAATTGGGCAAGCATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATTTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTATATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTGTGTAATGGATTAGTGCCACTGTCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCACACAACTAATGTCATTAAATATCATTTTTGAATGTATATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCATATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGATGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGCTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATGGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACTTATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCATAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAGATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATAATTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTACTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGAGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTATAAGTAATTATAATATAATGAATGTAAAAAGGTTTATATATTCAATATTTTTTATAAAAAAAAAATCATTTCGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCTGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACATTCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATACCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACGCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATTTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTTCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCATTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATACATGGCTATCAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAATAAAATAATTATTCCTTACATCGTACCCATCAATATAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTAGATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGCCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGTCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCGGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCTGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCATCCCCATTTTGAATATTTTTATACGCTAATATACCGGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCTTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCACCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTCATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGCCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACTATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCATCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGTTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGCGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTTTGTTACAGTTTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATATATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGACGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCAACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGATAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGATGTTGAATAATCGTTATCATCATTTTGTAATTGTGACATCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAACGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACACGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTCGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGCTGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATTGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGGCCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCCGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATAGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGATGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGTTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACGCATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGAACTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGTATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCGCATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTATAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGTGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAACATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCGTCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGTACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAAGATAGTAAAAATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACCGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATACCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGTGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACCGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCCAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCGCAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCAACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGAAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGACATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGCGGACATTTTCTAGTTACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGCGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACGAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTACAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTGCCGAAAATAATCAGCACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGCGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTTCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCGCCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAACATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGCAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATAGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTATATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATCGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCATACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACTGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGAGATAAGAACATTATAATAATCAATAATATATCTTATATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAAACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGCATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTGTAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCTACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGCGTTATCGGGACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATTTACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTGTCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAATAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCTCCGCTTCTATTTACTCCCGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACATCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAGAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAGTGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTGAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACGTCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCGCCGCCACCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACACGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTGATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACTGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATACGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGAGAAATAATCATAAATTATTTCATTATCGTGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAATTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGAGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTACTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCGTTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATACCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTACAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCGACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGTGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGATGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTACCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGACCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTATGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGAGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTGCAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCAACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATCGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAAGATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAGAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGTAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGACAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAGTCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGCCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGCGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATACCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGAACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTGCTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGTCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGACATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAATACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGACCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATTATTAATACATTTATATCCAACATATGGTACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAGGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCACCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGCCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGTCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACGCATTTCGTTTATCATTGTTACTATTACTATTACTATTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTTTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCGCCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTTGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATACAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGACCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCAAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCTGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCGAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAGATAATAGCAATATTAGTTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGCGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGGAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATTATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATCTTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATCCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTCTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTACGTTTCTTTTTCTAGATCGACAATCTTTCTCAACATTTCATCCCCATGCCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCAACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCATCATTAGATTTACAGGCTGTTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTATAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGCAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTCCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATGACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATACATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATGTTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATAATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTGGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCGATATTTATTTTGCTATCTTGATAATGTCCTGTATCAGTTGCATTTTCAGCACTCGACTGAATATTAGCACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATGTGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCGAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATGATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCGTTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACATCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACAAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACGAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGCGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATATACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACCGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATGTAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAACACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATCAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACAATTACAATACATTTTTATCATAACACTACTTCGGTTAGATGTTTTAGAAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGTCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCACGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGTCATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCGCACCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGTACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCTTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAAATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACAGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTTTATAGTATGATGGATATGATGGATATGATGGATATGATGGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGTATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACTAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCATATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAACGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGACGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTGGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGTGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATATGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTTCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTAATTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGTATATACCTACTTCGTCACTTCCACACGCTCCAGAAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGGTGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTATAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCGCTACTTGGTTAGTGTGTATTATTCAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCTCATAGATTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACGATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGCCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAATATCCTCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATGTACCGACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTGGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGGAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGATATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCGCGACTCCGGAACCAATTACTGATAATGTAGAAGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGAATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGTGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTATGGAACTTCTAAAACAGCTGTAAATACAGCGGCTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGAGCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCACATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACGTGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGCGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTAAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAGTGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTGGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCACGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATACGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTCGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGCGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATGCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACTGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAAGATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGCATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACCGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCCATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTCTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTGATAAGGACATTGGATATGTGGAAAAGATGATGGTGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATGTTACAAATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCGACAACTGGACACGGGAACGTGGTATAAAGTATTTAGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCGAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTATAGAGTGTGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTAACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGGAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAGCACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGCCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGACCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATGCATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACGCAGATATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATAGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGCAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATGTATTACGAAGAAGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAATGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACATGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTATAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATGCATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATTGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGCATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAAACATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGAAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGCGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACGTGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTGGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACACCTATGATAGTGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACGTATTAAAATGCACCGACTAAGAACGTAGAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAGGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAACGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATATACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATAGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGGCAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTGCATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTAATTAACAACATAACTCTGACAAATATTATACGCAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGGTGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGATGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTACAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTATCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGGCCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACGCTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTTCCTGTCTTTATTGGAGATTACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTTCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATCTGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGTGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACTATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGATGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGGATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACCGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGGCCTTCATCATTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCGATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGTATATATCGTTAAAAATCTGTAAGAGGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTTACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGAAGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATTGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATCGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTTATAAGTAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTTATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGAACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGCGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCTGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATCATATACAAGGCGGATGTCGTTAATGACATCATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACCTATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAATCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGAGAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAACGGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCCATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTTACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAATATTTTTATTCTATTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGG +>ON843165 +TAATTAATTTAATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTTTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTTGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGAGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGAGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGNNNNNNNNGCNNNNNNNNNNNNNTTTCACGACGACCTCGATCNNNNNNNNNTNNCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATTAAATTAATTA +>KJ642617 +CGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATGATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATCGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCATACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAGATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTCGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTCGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACGCATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCGTCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAAGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACCGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCCAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACGAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGCATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGATGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATATATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGATGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGCGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGTCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACCCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAGATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGGCTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTCTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTACGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCRTCATCATSATCATCATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCGTTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACGAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGCGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACCGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGTCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCATGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAAATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCTATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCATGTAGGTCTTATCACGTGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAAGATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGGAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAGAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATCATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCG diff --git a/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/tree.json b/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/tree.json new file mode 100644 index 00000000..fc6c9085 --- /dev/null +++ b/data_output/nextstrain/mpox/all-clades/rivers-with-ancestral-snps/unreleased/tree.json @@ -0,0 +1 @@ +{"version":"v2","meta":{"title":"Nextclade reference tree for MPXV (reconstructed ancestral reference seq in NC_063383.1 coordinates)","updated":"2023-11-16","build_url":"https://github.com/nextstrain/monkeypox","data_provenance":[{"name":"GenBank","url":"https://www.ncbi.nlm.nih.gov/genbank/"}],"maintainers":[{"name":"Nextstrain team","url":"http://nextstrain.org"}],"display_defaults":{"color_by":"clade_membership","map_triplicate":false,"distance_measure":"div","tip_label":"strain_display","transmission_lines":false},"genome_annotations":{"OPG001":{"end":1575,"seqid":"resources/genome_annotation.gff3","start":835,"strand":"-","type":"gene"},"OPG001_dup":{"end":196375,"seqid":"resources/genome_annotation.gff3","start":195635,"strand":"+","type":"gene"},"OPG002":{"end":2751,"seqid":"resources/genome_annotation.gff3","start":1702,"strand":"-","type":"gene"},"OPG002_dup":{"end":195508,"seqid":"resources/genome_annotation.gff3","start":194459,"strand":"+","type":"gene"},"OPG003":{"end":4607,"seqid":"resources/genome_annotation.gff3","start":2841,"strand":"-","type":"gene"},"OPG003_dup":{"end":194369,"seqid":"resources/genome_annotation.gff3","start":192603,"strand":"+","type":"gene"},"OPG005":{"end":189660,"seqid":"resources/genome_annotation.gff3","start":189199,"strand":"+","type":"gene"},"OPG015":{"end":6156,"seqid":"resources/genome_annotation.gff3","start":4843,"strand":"-","type":"gene"},"OPG015_dup":{"end":192367,"seqid":"resources/genome_annotation.gff3","start":191054,"strand":"+","type":"gene"},"OPG016":{"end":190940,"seqid":"resources/genome_annotation.gff3","start":190410,"strand":"+","type":"gene"},"OPG019":{"end":8008,"seqid":"resources/genome_annotation.gff3","start":7580,"strand":"+","type":"gene"},"OPG021":{"end":10315,"seqid":"resources/genome_annotation.gff3","start":9587,"strand":"+","type":"gene"},"OPG022":{"end":10858,"seqid":"resources/genome_annotation.gff3","start":10478,"strand":"-","type":"gene"},"OPG023":{"end":12900,"seqid":"resources/genome_annotation.gff3","start":10918,"strand":"-","type":"gene"},"OPG024":{"end":13228,"seqid":"resources/genome_annotation.gff3","start":13034,"strand":"-","type":"gene"},"OPG025":{"end":15267,"seqid":"resources/genome_annotation.gff3","start":13375,"strand":"-","type":"gene"},"OPG027":{"end":16377,"seqid":"resources/genome_annotation.gff3","start":15925,"strand":"-","type":"gene"},"OPG029":{"end":17069,"seqid":"resources/genome_annotation.gff3","start":16602,"strand":"-","type":"gene"},"OPG030":{"end":17833,"seqid":"resources/genome_annotation.gff3","start":17213,"strand":"-","type":"gene"},"OPG031":{"end":18828,"seqid":"resources/genome_annotation.gff3","start":17878,"strand":"-","type":"gene"},"OPG034":{"end":20005,"seqid":"resources/genome_annotation.gff3","start":19361,"strand":"-","type":"gene"},"OPG035":{"end":20404,"seqid":"resources/genome_annotation.gff3","start":20051,"strand":"-","type":"gene"},"OPG036":{"end":21064,"seqid":"resources/genome_annotation.gff3","start":20531,"strand":"-","type":"gene"},"OPG037":{"end":22433,"seqid":"resources/genome_annotation.gff3","start":21105,"strand":"-","type":"gene"},"OPG038":{"end":23159,"seqid":"resources/genome_annotation.gff3","start":22497,"strand":"-","type":"gene"},"OPG039":{"end":24118,"seqid":"resources/genome_annotation.gff3","start":23264,"strand":"-","type":"gene"},"OPG040":{"end":25478,"seqid":"resources/genome_annotation.gff3","start":24351,"strand":"-","type":"gene"},"OPG042":{"end":27097,"seqid":"resources/genome_annotation.gff3","start":25823,"strand":"-","type":"gene"},"OPG043":{"end":27955,"seqid":"resources/genome_annotation.gff3","start":27125,"strand":"-","type":"gene"},"OPG044":{"end":28540,"seqid":"resources/genome_annotation.gff3","start":28091,"strand":"+","type":"gene"},"OPG045":{"end":29262,"seqid":"resources/genome_annotation.gff3","start":28603,"strand":"-","type":"gene"},"OPG046":{"end":29729,"seqid":"resources/genome_annotation.gff3","start":29274,"strand":"-","type":"gene"},"OPG047":{"end":31194,"seqid":"resources/genome_annotation.gff3","start":29746,"strand":"-","type":"gene"},"OPG048":{"end":32164,"seqid":"resources/genome_annotation.gff3","start":31205,"strand":"-","type":"gene"},"OPG049":{"end":33151,"seqid":"resources/genome_annotation.gff3","start":32195,"strand":"-","type":"gene"},"OPG050":{"end":33408,"seqid":"resources/genome_annotation.gff3","start":33181,"strand":"-","type":"gene"},"OPG051":{"end":33649,"seqid":"resources/genome_annotation.gff3","start":33425,"strand":"-","type":"gene"},"OPG052":{"end":33995,"seqid":"resources/genome_annotation.gff3","start":33801,"strand":"-","type":"gene"},"OPG053":{"end":34690,"seqid":"resources/genome_annotation.gff3","start":34052,"strand":"-","type":"gene"},"OPG054":{"end":35996,"seqid":"resources/genome_annotation.gff3","start":34677,"strand":"-","type":"gene"},"OPG055":{"end":37083,"seqid":"resources/genome_annotation.gff3","start":36019,"strand":"-","type":"gene"},"OPG056":{"end":39034,"seqid":"resources/genome_annotation.gff3","start":37127,"strand":"-","type":"gene"},"OPG057":{"end":40195,"seqid":"resources/genome_annotation.gff3","start":39077,"strand":"-","type":"gene"},"OPG058":{"end":40434,"seqid":"resources/genome_annotation.gff3","start":40213,"strand":"-","type":"gene"},"OPG059":{"end":40633,"seqid":"resources/genome_annotation.gff3","start":40484,"strand":"-","type":"gene"},"OPG060":{"end":41182,"seqid":"resources/genome_annotation.gff3","start":40706,"strand":"-","type":"gene"},"OPG061":{"end":41884,"seqid":"resources/genome_annotation.gff3","start":41189,"strand":"-","type":"gene"},"OPG062":{"end":42252,"seqid":"resources/genome_annotation.gff3","start":41947,"strand":"+","type":"gene"},"OPG063":{"end":43688,"seqid":"resources/genome_annotation.gff3","start":42249,"strand":"-","type":"gene"},"OPG064":{"end":45898,"seqid":"resources/genome_annotation.gff3","start":43685,"strand":"-","type":"gene"},"OPG065":{"end":46483,"seqid":"resources/genome_annotation.gff3","start":46022,"strand":"-","type":"gene"},"OPG066":{"end":47428,"seqid":"resources/genome_annotation.gff3","start":46649,"strand":"-","type":"gene"},"OPG068":{"end":49904,"seqid":"resources/genome_annotation.gff3","start":48201,"strand":"+","type":"gene"},"OPG069":{"end":50486,"seqid":"resources/genome_annotation.gff3","start":49986,"strand":"+","type":"gene"},"OPG070":{"end":51411,"seqid":"resources/genome_annotation.gff3","start":50590,"strand":"+","type":"gene"},"OPG071":{"end":54438,"seqid":"resources/genome_annotation.gff3","start":51418,"strand":"-","type":"gene"},"OPG072":{"end":54757,"seqid":"resources/genome_annotation.gff3","start":54470,"strand":"+","type":"gene"},"OPG073":{"end":55141,"seqid":"resources/genome_annotation.gff3","start":54752,"strand":"-","type":"gene"},"OPG074":{"end":57125,"seqid":"resources/genome_annotation.gff3","start":55128,"strand":"-","type":"gene"},"OPG075":{"end":57498,"seqid":"resources/genome_annotation.gff3","start":57172,"strand":"-","type":"gene"},"OPG076":{"end":57630,"seqid":"resources/genome_annotation.gff3","start":57523,"strand":"-","type":"gene"},"OPG077":{"end":58583,"seqid":"resources/genome_annotation.gff3","start":57645,"strand":"-","type":"gene"},"OPG078":{"end":58811,"seqid":"resources/genome_annotation.gff3","start":58590,"strand":"-","type":"gene"},"OPG079":{"end":59621,"seqid":"resources/genome_annotation.gff3","start":58812,"strand":"-","type":"gene"},"OPG080":{"end":62018,"seqid":"resources/genome_annotation.gff3","start":59703,"strand":"-","type":"gene"},"OPG081":{"end":62285,"seqid":"resources/genome_annotation.gff3","start":62046,"strand":"-","type":"gene"},"OPG082":{"end":63452,"seqid":"resources/genome_annotation.gff3","start":62304,"strand":"-","type":"gene"},"OPG083":{"end":64716,"seqid":"resources/genome_annotation.gff3","start":63445,"strand":"-","type":"gene"},"OPG084":{"end":66752,"seqid":"resources/genome_annotation.gff3","start":64722,"strand":"+","type":"gene"},"OPG085":{"end":68531,"seqid":"resources/genome_annotation.gff3","start":66756,"strand":"-","type":"gene"},"OPG086":{"end":68863,"seqid":"resources/genome_annotation.gff3","start":68528,"strand":"-","type":"gene"},"OPG087":{"end":69519,"seqid":"resources/genome_annotation.gff3","start":68857,"strand":"+","type":"gene"},"OPG088":{"end":69863,"seqid":"resources/genome_annotation.gff3","start":69489,"strand":"-","type":"gene"},"OPG089":{"end":71170,"seqid":"resources/genome_annotation.gff3","start":69866,"strand":"+","type":"gene"},"OPG090":{"end":71370,"seqid":"resources/genome_annotation.gff3","start":71179,"strand":"+","type":"gene"},"OPG091":{"end":71867,"seqid":"resources/genome_annotation.gff3","start":71370,"strand":"+","type":"gene"},"OPG092":{"end":72947,"seqid":"resources/genome_annotation.gff3","start":71832,"strand":"-","type":"gene"},"OPG093":{"end":73760,"seqid":"resources/genome_annotation.gff3","start":72978,"strand":"+","type":"gene"},"OPG094":{"end":74802,"seqid":"resources/genome_annotation.gff3","start":73780,"strand":"+","type":"gene"},"OPG095":{"end":75555,"seqid":"resources/genome_annotation.gff3","start":74803,"strand":"+","type":"gene"},"OPG096":{"end":75865,"seqid":"resources/genome_annotation.gff3","start":75587,"strand":"+","type":"gene"},"OPG097":{"end":76875,"seqid":"resources/genome_annotation.gff3","start":75841,"strand":"-","type":"gene"},"OPG098":{"end":77655,"seqid":"resources/genome_annotation.gff3","start":76900,"strand":"+","type":"gene"},"OPG099":{"end":78051,"seqid":"resources/genome_annotation.gff3","start":77665,"strand":"+","type":"gene"},"OPG100":{"end":78466,"seqid":"resources/genome_annotation.gff3","start":78008,"strand":"+","type":"gene"},"OPG101":{"end":79019,"seqid":"resources/genome_annotation.gff3","start":78486,"strand":"+","type":"gene"},"OPG102":{"end":80086,"seqid":"resources/genome_annotation.gff3","start":79085,"strand":"+","type":"gene"},"OPG103":{"end":80558,"seqid":"resources/genome_annotation.gff3","start":80001,"strand":"+","type":"gene"},"OPG104":{"end":81019,"seqid":"resources/genome_annotation.gff3","start":80618,"strand":"-","type":"gene"},"OPG105":{"end":84986,"seqid":"resources/genome_annotation.gff3","start":81126,"strand":"+","type":"gene"},"OPG106":{"end":85498,"seqid":"resources/genome_annotation.gff3","start":84983,"strand":"-","type":"gene"},"OPG107":{"end":86081,"seqid":"resources/genome_annotation.gff3","start":85512,"strand":"+","type":"gene"},"OPG108":{"end":87059,"seqid":"resources/genome_annotation.gff3","start":86085,"strand":"-","type":"gene"},"OPG109":{"end":89447,"seqid":"resources/genome_annotation.gff3","start":87060,"strand":"-","type":"gene"},"OPG110":{"end":90264,"seqid":"resources/genome_annotation.gff3","start":89632,"strand":"+","type":"gene"},"OPG111":{"end":91209,"seqid":"resources/genome_annotation.gff3","start":90265,"strand":"+","type":"gene"},"OPG112":{"end":91687,"seqid":"resources/genome_annotation.gff3","start":91247,"strand":"+","type":"gene"},"OPG113":{"end":94268,"seqid":"resources/genome_annotation.gff3","start":91731,"strand":"+","type":"gene"},"OPG114":{"end":94667,"seqid":"resources/genome_annotation.gff3","start":94227,"strand":"-","type":"gene"},"OPG115":{"end":95361,"seqid":"resources/genome_annotation.gff3","start":94660,"strand":"+","type":"gene"},"OPG116":{"end":96017,"seqid":"resources/genome_annotation.gff3","start":95361,"strand":"+","type":"gene"},"OPG117":{"end":98406,"seqid":"resources/genome_annotation.gff3","start":96049,"strand":"+","type":"gene"},"OPG118":{"end":100359,"seqid":"resources/genome_annotation.gff3","start":98446,"strand":"+","type":"gene"},"OPG119":{"end":100871,"seqid":"resources/genome_annotation.gff3","start":100386,"strand":"+","type":"gene"},"OPG120":{"end":101748,"seqid":"resources/genome_annotation.gff3","start":100834,"strand":"-","type":"gene"},"OPG121":{"end":102431,"seqid":"resources/genome_annotation.gff3","start":101790,"strand":"+","type":"gene"},"OPG122":{"end":103174,"seqid":"resources/genome_annotation.gff3","start":102428,"strand":"+","type":"gene"},"OPG123":{"end":105070,"seqid":"resources/genome_annotation.gff3","start":103175,"strand":"-","type":"gene"},"OPG124":{"end":105968,"seqid":"resources/genome_annotation.gff3","start":105105,"strand":"-","type":"gene"},"OPG125":{"end":107654,"seqid":"resources/genome_annotation.gff3","start":105999,"strand":"-","type":"gene"},"OPG126":{"end":108130,"seqid":"resources/genome_annotation.gff3","start":107678,"strand":"-","type":"gene"},"OPG127":{"end":108825,"seqid":"resources/genome_annotation.gff3","start":108151,"strand":"-","type":"gene"},"OPG128":{"end":109055,"seqid":"resources/genome_annotation.gff3","start":108822,"strand":"-","type":"gene"},"OPG129":{"end":111004,"seqid":"resources/genome_annotation.gff3","start":109070,"strand":"-","type":"gene"},"OPG130":{"end":111902,"seqid":"resources/genome_annotation.gff3","start":111057,"strand":"-","type":"gene"},"OPG131":{"end":112425,"seqid":"resources/genome_annotation.gff3","start":111940,"strand":"+","type":"gene"},"OPG132":{"end":113540,"seqid":"resources/genome_annotation.gff3","start":112422,"strand":"-","type":"gene"},"OPG133":{"end":115696,"seqid":"resources/genome_annotation.gff3","start":113564,"strand":"-","type":"gene"},"OPG134":{"end":116628,"seqid":"resources/genome_annotation.gff3","start":115750,"strand":"+","type":"gene"},"OPG135":{"end":116911,"seqid":"resources/genome_annotation.gff3","start":116609,"strand":"-","type":"gene"},"OPG136":{"end":119587,"seqid":"resources/genome_annotation.gff3","start":116912,"strand":"-","type":"gene"},"OPG137":{"end":120558,"seqid":"resources/genome_annotation.gff3","start":119602,"strand":"+","type":"gene"},"OPG138":{"end":121132,"seqid":"resources/genome_annotation.gff3","start":120560,"strand":"-","type":"gene"},"OPG139":{"end":121368,"seqid":"resources/genome_annotation.gff3","start":121156,"strand":"-","type":"gene"},"OPG140":{"end":121746,"seqid":"resources/genome_annotation.gff3","start":121474,"strand":"-","type":"gene"},"OPG141":{"end":121924,"seqid":"resources/genome_annotation.gff3","start":121763,"strand":"-","type":"gene"},"OPG142":{"end":122198,"seqid":"resources/genome_annotation.gff3","start":121914,"strand":"-","type":"gene"},"OPG143":{"end":123315,"seqid":"resources/genome_annotation.gff3","start":122182,"strand":"-","type":"gene"},"OPG144":{"end":123932,"seqid":"resources/genome_annotation.gff3","start":123318,"strand":"-","type":"gene"},"OPG145":{"end":125425,"seqid":"resources/genome_annotation.gff3","start":123947,"strand":"+","type":"gene"},"OPG146":{"end":125639,"seqid":"resources/genome_annotation.gff3","start":125406,"strand":"-","type":"gene"},"OPG147":{"end":125987,"seqid":"resources/genome_annotation.gff3","start":125640,"strand":"-","type":"gene"},"OPG148":{"end":127266,"seqid":"resources/genome_annotation.gff3","start":125986,"strand":"+","type":"gene"},"OPG149":{"end":127759,"seqid":"resources/genome_annotation.gff3","start":127196,"strand":"+","type":"gene"},"OPG150":{"end":128927,"seqid":"resources/genome_annotation.gff3","start":127779,"strand":"+","type":"gene"},"OPG151":{"end":132418,"seqid":"resources/genome_annotation.gff3","start":128924,"strand":"+","type":"gene"},"OPG153":{"end":137667,"seqid":"resources/genome_annotation.gff3","start":136138,"strand":"-","type":"gene"},"OPG154":{"end":138050,"seqid":"resources/genome_annotation.gff3","start":137718,"strand":"-","type":"gene"},"OPG155":{"end":138491,"seqid":"resources/genome_annotation.gff3","start":138051,"strand":"-","type":"gene"},"OPG156":{"end":139409,"seqid":"resources/genome_annotation.gff3","start":138492,"strand":"-","type":"gene"},"OPG157":{"end":139608,"seqid":"resources/genome_annotation.gff3","start":139372,"strand":"-","type":"gene"},"OPG158":{"end":139769,"seqid":"resources/genome_annotation.gff3","start":139641,"strand":"-","type":"gene"},"OPG159":{"end":140205,"seqid":"resources/genome_annotation.gff3","start":139768,"strand":"+","type":"gene"},"OPG160":{"end":141074,"seqid":"resources/genome_annotation.gff3","start":140172,"strand":"-","type":"gene"},"OPG161":{"end":141647,"seqid":"resources/genome_annotation.gff3","start":141102,"strand":"+","type":"gene"},"OPG162":{"end":142158,"seqid":"resources/genome_annotation.gff3","start":141652,"strand":"+","type":"gene"},"OPG163":{"end":142732,"seqid":"resources/genome_annotation.gff3","start":142202,"strand":"+","type":"gene"},"OPG164":{"end":143464,"seqid":"resources/genome_annotation.gff3","start":142778,"strand":"+","type":"gene"},"OPG165":{"end":144322,"seqid":"resources/genome_annotation.gff3","start":143516,"strand":"+","type":"gene"},"OPG166":{"end":144577,"seqid":"resources/genome_annotation.gff3","start":144398,"strand":"+","type":"gene"},"OPG167":{"end":145407,"seqid":"resources/genome_annotation.gff3","start":144574,"strand":"-","type":"gene"},"OPG170":{"end":146778,"seqid":"resources/genome_annotation.gff3","start":146113,"strand":"-","type":"gene"},"OPG171":{"end":147389,"seqid":"resources/genome_annotation.gff3","start":146988,"strand":"+","type":"gene"},"OPG172":{"end":148017,"seqid":"resources/genome_annotation.gff3","start":147427,"strand":"+","type":"gene"},"OPG173":{"end":148261,"seqid":"resources/genome_annotation.gff3","start":148037,"strand":"+","type":"gene"},"OPG174":{"end":149395,"seqid":"resources/genome_annotation.gff3","start":148355,"strand":"-","type":"gene"},"OPG175":{"end":149819,"seqid":"resources/genome_annotation.gff3","start":149442,"strand":"+","type":"gene"},"OPG176":{"end":150531,"seqid":"resources/genome_annotation.gff3","start":149809,"strand":"+","type":"gene"},"OPG178":{"end":152123,"seqid":"resources/genome_annotation.gff3","start":151509,"strand":"+","type":"gene"},"OPG180":{"end":154371,"seqid":"resources/genome_annotation.gff3","start":152692,"strand":"+","type":"gene"},"OPG181":{"end":155416,"seqid":"resources/genome_annotation.gff3","start":154412,"strand":"+","type":"gene"},"OPG185":{"end":159858,"seqid":"resources/genome_annotation.gff3","start":158917,"strand":"+","type":"gene"},"OPG187":{"end":161533,"seqid":"resources/genome_annotation.gff3","start":160622,"strand":"+","type":"gene"},"OPG188":{"end":163107,"seqid":"resources/genome_annotation.gff3","start":161596,"strand":"+","type":"gene"},"OPG189":{"end":165018,"seqid":"resources/genome_annotation.gff3","start":163333,"strand":"+","type":"gene"},"OPG190":{"end":166075,"seqid":"resources/genome_annotation.gff3","start":165122,"strand":"+","type":"gene"},"OPG191":{"end":166667,"seqid":"resources/genome_annotation.gff3","start":166161,"strand":"+","type":"gene"},"OPG192":{"end":167279,"seqid":"resources/genome_annotation.gff3","start":166731,"strand":"+","type":"gene"},"OPG193":{"end":168137,"seqid":"resources/genome_annotation.gff3","start":167334,"strand":"+","type":"gene"},"OPG195":{"end":168895,"seqid":"resources/genome_annotation.gff3","start":168230,"strand":"+","type":"gene"},"OPG197":{"end":169972,"seqid":"resources/genome_annotation.gff3","start":169670,"strand":"+","type":"gene"},"OPG198":{"end":170886,"seqid":"resources/genome_annotation.gff3","start":170038,"strand":"+","type":"gene"},"OPG199":{"end":172022,"seqid":"resources/genome_annotation.gff3","start":170988,"strand":"+","type":"gene"},"OPG200":{"end":172599,"seqid":"resources/genome_annotation.gff3","start":172150,"strand":"+","type":"gene"},"OPG204":{"end":175587,"seqid":"resources/genome_annotation.gff3","start":174532,"strand":"+","type":"gene"},"OPG205":{"end":178019,"seqid":"resources/genome_annotation.gff3","start":175656,"strand":"+","type":"gene"},"OPG208":{"end":180339,"seqid":"resources/genome_annotation.gff3","start":179266,"strand":"+","type":"gene"},"OPG209":{"end":181090,"seqid":"resources/genome_annotation.gff3","start":180518,"strand":"+","type":"gene"},"OPG210":{"end":186998,"seqid":"resources/genome_annotation.gff3","start":181356,"strand":"+","type":"gene"},"nuc":{"end":197209,"start":1,"strand":"+","type":"source"}},"colorings":[{"key":"clade_membership","title":"Clade","type":"categorical","scale":[["I","#4A8CC2"],["II","#71B486"],["IIa","#ABBD52"],["IIb","#DEA73C"]]},{"key":"gt","title":"Genotype","type":"categorical"},{"key":"outbreak","title":"Outbreak","type":"categorical","scale":[["hMPXV-1","#4C90C0"]]},{"key":"lineage","title":"Lineage","type":"categorical","scale":[["A","#5E1D9D"],["A.1","#4D22AE"],["A.1.1","#4531BC"],["B.1","#4041C7"],["B.1.1","#3F53CD"],["B.1.2","#4064CF"],["B.1.3","#4375CD"],["C.1","#4784C8"],["B.1.4","#4C91BF"],["B.1.5","#539CB4"],["B.1.6","#5AA5A7"],["B.1.7","#63AC9A"],["B.1.8","#6CB28C"],["B.1.9","#77B67E"],["B.1.10","#82BA71"],["B.1.11","#8FBC66"],["B.1.12","#9CBE5B"],["B.1.13","#A9BD53"],["B.1.14","#B5BD4C"],["B.1.15","#C1BA46"],["B.1.16","#CDB642"],["B.1.17","#D6B03F"],["B.1.18","#DEA73B"],["B.1.19","#E39B39"],["B.1.20","#E68D36"],["A.2","#E67C33"],["A.2.1","#E5692F"],["A.2.2","#E1532B"],["A.2.3","#DE3E27"],["A.3","#DB2823"]]},{"key":"date","title":"Collection Date","type":"categorical"},{"key":"host","title":"Host","type":"categorical"},{"key":"strain","title":"Strain name","type":"categorical"},{"key":"strain_display","title":"Pretty strain name","type":"categorical"},{"key":"region","title":"Region","type":"categorical","scale":[["Asia","#447CCD"],["Oceania","#5EA9A1"],["Africa","#8ABB6A"],["Europe","#BEBB48"],["South America","#E29E39"],["North America","#E2562B"]]},{"key":"country","title":"Country","type":"categorical","scale":[["Israel","#5E1D9D"],["Singapore","#4F1FAA"],["Vietnam","#4929B4"],["Taiwan","#4333BE"],["South Korea","#403FC6"],["Japan","#3F4CCB"],["Australia","#3E59CF"],["Sierra Leone","#4066CF"],["Liberia","#4272CE"],["C\u00f4te d'Ivoire","#447ECC"],["Benin","#4887C6"],["Nigeria","#4C91C0"],["Gabon","#5199B8"],["Cameroon","#56A0AF"],["Republic of the Congo","#5BA7A6"],["Central African Republic","#62AB9C"],["Democratic Republic of the Congo","#69B091"],["South Africa","#70B487"],["Portugal","#78B67E"],["Ireland","#80B974"],["Spain","#89BB6B"],["United Kingdom","#92BC63"],["France","#9BBE5B"],["Belgium","#A4BE56"],["Netherlands","#AEBD50"],["Switzerland","#B7BD4B"],["Germany","#C0BB47"],["Italy","#C8B843"],["Slovenia","#D0B441"],["Sweden","#D6AF3E"],["Austria","#DDAA3C"],["Czech Republic","#E0A23A"],["Slovakia","#E49938"],["Romania","#E68F36"],["Finland","#E68234"],["Brazil","#E67631"],["Peru","#E4672E"],["Colombia","#E2572B"],["Mexico","#DF4728"],["USA","#DD3826"],["Canada","#DB2823"]]}],"filters":["clade_membership","lineage","country","host","institution","region"],"panels":["tree","entropy"],"extensions":{"nextclade":{"clade_node_attrs":[{"name":"outbreak","displayName":"Outbreak","description":""},{"name":"lineage","displayName":"Lineage","description":""}]}}},"tree":{"name":"NODE_0000000","node_attrs":{"div":0,"clade_membership":{"value":"outgroup"}},"branch_attrs":{"mutations":{},"labels":{"clade":"outgroup"}},"children":[{"name":"reconstructed_ancestral_mpox","node_attrs":{"div":0,"clade_membership":{"value":"outgroup"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000001","node_attrs":{"div":1,"clade_membership":{"value":"outgroup"}},"branch_attrs":{"mutations":{"nuc":["T607-","T608-","T609-","C29758T","A32210-","C32211-","G32212-","A39072-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","A158170-","T166656-","T166657-","G169772-","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","T179226C","T190396-","A196615-","A196616-","A196617-"],"OPG049":["R314-"],"OPG153":["M370-","M371-"],"OPG159":["N124-","Y125-","N126-"],"OPG191":["F166-"]},"labels":{"aa":"OPG049: R314-; OPG153: M370-, M371-; OPG159: N124-, Y125-, N126-; OPG191: F166-"}},"children":[{"name":"NODE_0000002","node_attrs":{"div":254,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G475A","T600-","T601-","T602-","T603-","T604-","T605-","T606-","G749A","A1309G","G2239-","A2240-","C2241-","C2659T","C3143T","G4042A","C4693-","T4694-","T4695-","A4696-","A4697-","C4698-","T4699-","A4700-","A4701-","C4702-","T4703-","T4704-","A4705-","T4706-","G4707-","A4708-","C4709-","T4710-","T4711-","A4712-","A4713-","C4714-","T4715-","A4716-","A4717-","C4718-","T4719-","T4720-","A4721-","T4722-","G4723-","A4724-","C4725-","T4726-","T4727-","A4728-","A4729-","C4730-","T4731-","A4732-","A4733-","C4734-","T4735-","T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","A4748-","A4749-","C4750-","T4751-","T4752-","A4753-","T4754-","G4755-","A4756-","C4757-","T4758-","T4759-","A4760-","A4761-","C4762-","T4763-","A4764-","A4765-","C4766-","T4767-","T4768-","A4769-","T4770-","G4771-","A4772-","C4773-","T4774-","T4775-","C5809T","T6159C","T6429-","A6430-","G7021-","C7022-","T7023-","C7024-","T7025-","C7026-","C7148-","T7149-","A7150-","T7151-","G7205A","T7405-","T7411C","A8055-","G8277A","T8328-","T8329-","A8421-","C8422-","A8423-","T8424-","A8471-","T8499-","C8603A","A8810G","A8830G","T8919-","T8993-","G9139A","A9282-","C9404T","A9529-","C10242T","A11097T","C11625T","A11991G","G12128A","C12574A","A13276-","T13353-","C14647T","T15281C","A15549-","T15550-","A15657T","A15872-","C15883A","C16002T","G16102A","T16239C","A16617-","T16618-","C16619-","A16620-","T16621-","C16622-","G17525A","A18055-","C18056-","C18057-","C18107T","G18590A","A19086G","T19282G","C22003T","C23283T","C23648T","A24310-","C24338-","A25528T","G25777A","C27692T","T28278C","A28415G","A28590-","G28591-","T28592-","G28593-","T28594-","T28595-","A28596-","A28597-","A28598-","A28599-","A28600-","A28601-","A28602-","T28603-","T28604-","A28605-","T28606-","C28607-","C28608-","T29029C","G29923A","C30730T","C31081T","C31529T","G31955A","C33159T","A33199-","T33414-","C35352A","G36445A","G40501A","A41207G","C41735T","A41861G","T41935-","C44387T","G44966A","G46303T","G46421A","C46435T","A46506-","C46507-","A46508-","T46583G","T46596-","G46610A","T46648-","T46760C","A47576-","A47700-","C47701-","G47966A","C48041T","G48062T","A48166-","G48167-","T48168-","C48392T","C48951T","C49139T","G49859T","C49957T","C50500-","T50501-","T50575-","A50576-","C51202T","G53269T","G54352T","G54497A","T57433C","C57572T","G57622A","A58872G","T59648C","G60274T","A60457G","G60753A","G62250A","C62649T","T66650C","G67611A","A68297T","A68795G","C69896T","C70774A","C71035T","A71205G","G71553A","G71587A","A72217T","C72231T","C73350T","T82688C","T84290C","C84927T","A86247G","G86728A","C87560T","T88356A","G88746A","A89276G","C90820T","G93339A","C94061T","G94623A","G95280A","C97134A","G97408A","G98202A","A98856G","G100445A","T101536C","C101694T","C103006A","C103764T","C103805A","C104134T","A104556G","C104840T","G106554A","G107118C","C107322A","G107764A","G109874A","G111095T","A111303G","G111715A","G112206A","A112221G","C112455T","A113916G","G113924A","T114770C","C115676T","A116427C","T116735C","C117047T","G118640A","A118740T","C118789T","C118903T","G119474A","G123382A","A124691G","C124714A","A125365G","G126603A","T127137C","A128940T","A129767G","C131809T","G132286A","T132813-","G132887A","T133084-","T133085-","T133086-","T133087-","T133088-","T133089-","T133090-","T133091-","T133092-","T133093-","T133094-","T133095-","T133096-","T133097-","T133098-","T133177-","C133178-","T133179-","T133180-","T133181-","C133182-","T133183-","C133184-","A133185-","A133186-","T133224C","G133368A","T133493-","C133494-","G133495-","G133496-","T133497-","C133498-","C133499-","A133500-","T133501-","G133502-","T133503-","C133504-","T133505-","C133506-","C133507-","A133508-","T133509-","T133510-","G133511-","C133512-","T133513-","A133514-","C133515-","A133516-","C133517-","C133518-","A133519-","C133520-","C133521-","A133522-","T133523-","T133524-","A133525-","G133526-","A133527-","T133528-","T133529-","T133530-","A133531-","C133532-","A133533-","G133534-","G133535-","C133536-","T133537-","G133538-","C133539-","T133540-","A133541-","G133542-","T133543-","T133544-","G133545-","T133546-","C133547-","G133548-","T133549-","T133550-","C133551-","G133552-","A133553-","G133554-","A133555-","T133556-","C133557-","A133558-","G133559-","A133560-","A133561-","A133562-","T133563-","A133564-","C133565-","G133566-","T133567-","G133568-","T133569-","T133570-","T133571-","T133572-","C133573-","T133574-","T133575-","G133576-","G133577-","A133578-","A133579-","T133580-","G133581-","G133582-","A133583-","T133584-","T133585-","T133586-","C133587-","G133588-","T133589-","C133590-","G133591-","A133592-","T133593-","G133594-","T133595-","A133596-","C133597-","T133598-","T133599-","G133600-","T133601-","C133602-","A133603-","T133604-","G133605-","A133606-","T133607-","T133608-","G133609-","G133610-","C133611-","A133612-","T133613-","C133614-","G133615-","A133616-","A133617-","A133618-","C133619-","A133620-","C133621-","T133622-","T133623-","A133624-","T133625-","T133626-","A133627-","A133628-","G133629-","T133630-","T133631-","C133632-","T133633-","T133634-","T133635-","T133636-","T133637-","T133638-","T133639-","C133640-","A133641-","A133642-","T133643-","T133644-","C133645-","T133646-","A133647-","C133648-","G133649-","A133650-","T133651-","T133652-","T133653-","T133654-","A133655-","T133656-","T133657-","T133658-","C133659-","T133660-","T133661-","T133662-","C133663-","G133664-","C133665-","G133666-","A133667-","G133668-","T133669-","C133670-","A133671-","A133672-","T133673-","T133674-","C133675-","C133676-","C133677-","T133678-","C133679-","C133680-","T133681-","G133682-","T133683-","A133684-","G133685-","T133686-","A133687-","A133688-","C133689-","T133690-","A133691-","T133692-","C133693-","A133694-","G133695-","T133696-","T133697-","T133698-","T133699-","G133700-","T133701-","C133702-","A133703-","G133704-","A133705-","T133706-","T133707-","C133708-","A133709-","C133710-","G133711-","C133712-","T133713-","C133714-","T133715-","C133716-","T133717-","A133718-","C133719-","G133720-","T133721-","A133722-","G133723-","A133724-","C133725-","T133726-","T133727-","T133728-","C133729-","T133730-","T133731-","G133732-","C133733-","A133734-","A133735-","G133736-","T133737-","T133738-","A133739-","C133740-","T133741-","A133742-","A133743-","T133744-","T133745-","T133746-","G133747-","T133748-","T133749-","C133750-","C133751-","C133752-","T133753-","G133754-","G133755-","C133756-","A133757-","T133758-","T133759-","A133760-","C133761-","C133762-","G133763-","A133764-","G133765-","T133766-","T133767-","C133768-","A133769-","G133770-","T133771-","T133772-","T133773-","T133774-","A133775-","T133776-","A133777-","T133778-","G133779-","C133780-","C133781-","G133782-","A133783-","A133784-","T133785-","A133786-","G133787-","A133788-","G133789-","T133790-","T133791-","C133792-","T133793-","G133794-","A133795-","T133796-","T133797-","C133798-","A133799-","T133800-","C133801-","C133802-","T133803-","T133804-","T133805-","G133806-","A133807-","G133808-","A133809-","A133810-","G133811-","A133812-","T133813-","C133814-","T133815-","C133816-","T133817-","A133818-","G133819-","C133820-","G133821-","A133822-","T133823-","C133824-","G133825-","T133826-","T133827-","C133828-","A133829-","A133830-","G133831-","A133832-","T133833-","C133834-","C133835-","C133836-","T133837-","G133838-","A133839-","T133840-","T133841-","C133842-","T133843-","A133844-","G133845-","T133846-","C133847-","T133848-","T133849-","T133850-","A133851-","G133852-","C133853-","C133854-","T133855-","A133856-","T133857-","T133858-","T133859-","A133860-","C133861-","C133862-","T133863-","C133864-","C133865-","T133866-","C133867-","A133868-","G133869-","A133870-","A133871-","G133872-","A133873-","T133874-","G133875-","C133876-","T133877-","C133878-","C133879-","G133880-","T133881-","T133882-","A133883-","C133884-","C133885-","G133886-","T133887-","T133888-","T133889-","T133890-","T133891-","A133892-","C133893-","A133894-","A133895-","T133896-","C133897-","G133898-","T133899-","T133900-","A133901-","A133902-","G133903-","A133904-","T133905-","G133906-","T133907-","C133908-","T133909-","A133910-","T133911-","C133912-","A133913-","A133914-","G133915-","A133916-","T133917-","C133918-","C133919-","A133920-","T133921-","G133922-","A133923-","T133924-","T133925-","C133926-","T133927-","A133928-","T133929-","C133930-","T133931-","C133932-","T133933-","T133934-","T133935-","T133936-","C133937-","C133938-","A133939-","T133940-","A133941-","T133942-","C133943-","A133944-","G133945-","C134152T","G134354T","A135987T","G136015A","C136390A","A136864C","C137830T","T138627C","G138840T","T139429-","T139430-","G139431-","G141071A","A141497G","G141759A","G142056A","C142159T","T142338C","A142755-","G143459-","T143743G","G143831A","C144025T","G144742A","C145303T","G145642T","A145892-","G145908A","T145979-","A145980-","A145981-","C146084-","G146085-","C146395A","G146494A","G146632T","A146863-","T146864-","T146884-","T146885-","T146886-","A146887-","T146888-","A146889-","T146890-","T146891-","T146892-","T146893-","A146894-","T146895-","A146969-","C147489T","G147780A","C147800T","A148336-","T148344A","A150156G","T150539-","A150549T","A150968T","G151022-","A151023-","C151024-","A151025-","T151026-","A151043-","T151289G","A152267-","T152268-","T152269-","G152328A","G154263A","C154354-","T154355-","C154389T","T154664A","C154791A","T155424-","C155483A","G155888A","A156210-","T156371-","A156372-","C156373-","T156374-","G156375-","A156376-","C156377-","T156378-","A156379-","C156380-","A156381-","T156382-","G156383-","T156384-","A156385-","C156386-","T156387-","A156388-","T156389-","T156390-","T156391-","T156392-","A156393-","C156394-","A156395-","T156396-","T156397-","A156398-","C156399-","T156400-","A156401-","C156402-","A156403-","T156404-","T156405-","G156406-","G156407-","C156408-","T156409-","A156410-","C156411-","G156412-","G156413-","C156414-","A156415-","T156416-","A156417-","T156418-","A156419-","T156420-","A156421-","C156422-","C156423-","T156424-","A156425-","C156426-","T156427-","T156428-","C156429-","G156430-","T156431-","C156432-","A156433-","C156434-","T156435-","T156436-","C156437-","C156438-","A156439-","C156440-","A156441-","C156442-","G156443-","C156444-","T156445-","C156446-","C156447-","G156448-","G156449-","T156450-","A156451-","A156452-","A156453-","C156454-","G156455-","G156456-","G156457-","T156458-","G156459-","T156460-","C156461-","A156462-","T156463-","G156464-","T156465-","G156466-","A156467-","C156468-","G156469-","A156470-","G156471-","G156472-","G156473-","A156474-","G156475-","A156476-","A156477-","T156478-","C156479-","T156480-","T156481-","G156482-","A156483-","T156484-","A156485-","A156486-","G156487-","A156488-","G156489-","G156490-","C156491-","A156492-","T156493-","A156494-","A156495-","T156496-","C156497-","A156498-","A156499-","T156500-","G156501-","T156502-","T156503-","G156504-","T156505-","A156506-","A156507-","T156508-","C156509-","C156510-","G156511-","G156512-","T156513-","G156514-","T156515-","C156516-","C156517-","A156518-","C156519-","C156520-","T156521-","G156522-","G156523-","A156524-","G156525-","A156526-","A156527-","T156528-","T156529-","T156530-","G156531-","C156532-","C156533-","A156534-","A156535-","G156536-","G156537-","T156538-","C156539-","A156540-","G156541-","A156542-","T156543-","G156544-","T156545-","A156546-","G156547-","A156548-","G156549-","T156550-","T156551-","G156552-","G156553-","T156554-","A156555-","G156556-","T156557-","G156558-","A156559-","T156560-","A156561-","A156562-","C156563-","A156564-","C156565-","A156566-","A156567-","A156568-","A156569-","T156570-","G156571-","T156572-","G156573-","A156574-","A156575-","C156576-","A156577-","C156578-","T156579-","G156580-","C156581-","C156582-","C156583-","A156584-","C156585-","C156586-","T156587-","C156588-","A156589-","T156590-","A156591-","C156592-","A156593-","T156594-","A156595-","T156596-","A156597-","C156598-","C156599-","G156600-","C156601-","A156602-","A156603-","T156604-","C156605-","C156606-","C156607-","C156608-","A156609-","A156610-","T156611-","T156612-","A156613-","T156614-","T156615-","C156616-","T156617-","A156618-","A156619-","T156620-","A156621-","G156622-","A156623-","T156624-","G156625-","T156626-","C156627-","A156628-","T156629-","C156630-","A156631-","A156632-","T156633-","G156634-","T156635-","A156636-","G156637-","A156638-","A156639-","A156640-","A156641-","T156642-","G156643-","C156644-","C156645-","C156646-","A156647-","A156648-","C156649-","A156650-","G156651-","G156652-","A156653-","T156654-","C156655-","A156656-","T156657-","T156658-","T156659-","G156660-","A156661-","T156662-","A156663-","A156664-","G156665-","G156666-","T156667-","A156668-","A156669-","A156670-","G156671-","T156672-","G156673-","T156674-","A156675-","C156676-","C156677-","G156678-","G156679-","A156680-","A156681-","C156682-","A156683-","C156684-","A156685-","G156686-","A156687-","A156688-","C156689-","A156690-","A156691-","A156692-","T156693-","G156694-","T156695-","T156696-","C156697-","G156698-","T156699-","G156700-","T156701-","C156702-","A156703-","T156704-","C156705-","C156706-","T156707-","G156708-","G156709-","T156710-","T156711-","G156712-","G156713-","T156714-","A156715-","T156716-","A156717-","C156718-","G156719-","C156720-","T156721-","A156722-","C156723-","T156724-","G156725-","A156726-","T156727-","T156728-","C156729-","T156730-","T156731-","C156732-","A156733-","C156734-","A156735-","G156736-","A156737-","C156738-","T156739-","G156740-","A156741-","A156742-","G156743-","A156744-","T156745-","T156746-","G156747-","T156748-","C156749-","G156750-","A156751-","G156752-","A156753-","T156754-","T156755-","T156756-","G156757-","T156758-","G156759-","T156760-","A156761-","C156762-","C156763-","A156764-","A156765-","A156766-","A156767-","A156768-","A156769-","G156770-","G156771-","A156772-","G156773-","A156774-","T156775-","G156776-","T156777-","C156778-","C156779-","A156780-","T156781-","G156782-","C156783-","G156784-","G156785-","A156786-","T156787-","A156788-","C156789-","T156790-","T156791-","T156792-","G156793-","G156794-","T156795-","G156796-","G156797-","A156798-","A156799-","T156800-","A156801-","G156802-","A156803-","T156804-","G156805-","A156806-","A156807-","G156808-","G156809-","A156810-","A156811-","A156812-","T156813-","C156814-","C156815-","T156816-","A156817-","T156818-","T156819-","T156820-","G156821-","T156822-","A156823-","A156824-","A156825-","T156826-","C156827-","G156828-","T156829-","G156830-","T156831-","T156832-","G156833-","T156834-","G156835-","T156836-","T156837-","G156838-","G156839-","T156840-","G156841-","A156842-","A156843-","T156844-","A156845-","T156846-","T156847-","G156848-","C156849-","G156850-","A156851-","C156852-","T156853-","A156854-","C156855-","C156856-","T156857-","A156858-","C156859-","G156860-","T156861-","A156862-","A156863-","T156864-","T156865-","A156866-","T156867-","A156868-","G156869-","A156870-","C156871-","T156872-","T156873-","G156874-","A156875-","T156876-","C156877-","C156878-","A156879-","T156880-","T156881-","T156882-","C156883-","C156884-","T156885-","C156886-","C156887-","A156888-","T156889-","G156890-","C156891-","A156892-","A156893-","A156894-","C156895-","T156896-","A156897-","T156898-","C156899-","T156900-","A156901-","T156902-","C156903-","T156904-","A156905-","A156906-","A156907-","T156908-","G156909-","T156910-","A156911-","A156912-","T156913-","T156914-","A156915-","A156916-","T156917-","T156918-","A156919-","T156920-","G156921-","A156922-","T156923-","T156924-","T156925-","T156926-","G156927-","A156928-","T156929-","G156930-","A156931-","T156932-","A156933-","A156934-","T156935-","G156936-","T156937-","T156938-","A156939-","C156940-","C156941-","A156942-","T156943-","A156944-","C156945-","A156946-","T156947-","T156948-","A156949-","T156950-","A156951-","T156952-","C156953-","G156954-","C156955-","T156956-","A156957-","C156958-","T156959-","T156960-","G156961-","G156962-","T156963-","T156964-","A156965-","G156966-","T156967-","G156968-","T156969-","G156970-","T156971-","A156972-","T156973-","T156974-","A156975-","T156976-","T156977-","C156978-","A156979-","G156980-","T156981-","A156982-","T156983-","G156984-","G156985-","A156986-","A156987-","G156988-","A156989-","C156990-","C156991-","T156992-","A156993-","T156994-","T156995-","A156996-","A156997-","T156998-","A156999-","A157000-","T157001-","T157002-","A157003-","C157004-","T157005-","T157006-","A157007-","T157008-","C157009-","T157010-","T157011-","T157012-","T157013-","G157014-","A157015-","C157016-","G157017-","A157018-","T157019-","C157020-","T157021-","T157022-","G157023-","T157024-","T157025-","A157026-","T157027-","A157028-","A157029-","T157030-","T157031-","A157032-","T157033-","A157034-","A157035-","T157036-","A157037-","T157038-","A157039-","A157040-","A157041-","A157042-","A157043-","T157044-","A157045-","C157046-","T157047-","T157048-","A157049-","T157050-","G157051-","A157052-","C157053-","A157054-","T157055-","A157056-","G157057-","T157058-","A157059-","A157060-","C157061-","T157062-","C157063-","A157064-","T157065-","A157066-","A157067-","T157068-","T157069-","G157070-","C157071-","T157072-","G157073-","A157074-","C157075-","G157076-","C157077-","G157078-","A157079-","T157080-","A157081-","A157082-","A157083-","T157084-","T157085-","C157086-","G157087-","T157088-","A157089-","A157090-","T157091-","A157092-","A157093-","T157094-","C157095-","T157096-","G157097-","T157098-","T157099-","T157100-","T157101-","G157102-","T157103-","T157104-","C157105-","A157106-","A157107-","A157108-","T157109-","T157110-","T157111-","T157112-","T157113-","A157114-","T157115-","A157116-","A157117-","G157118-","G157119-","A157120-","A157121-","T157122-","C157123-","T157124-","A157125-","C157126-","A157127-","G157128-","G157129-","C157130-","A157131-","T157132-","A157133-","A157134-","A157135-","A157136-","A157137-","T157138-","A157139-","A157140-","A157141-","A157142-","A157143-","T157144-","A157145-","T157146-","A157147-","A157148-","T157149-","C157150-","T157151-","A157152-","T157153-","A157154-","A157155-","T157156-","A157157-","T157158-","A157159-","C157160-","T157161-","C157162-","T157163-","T157164-","A157165-","C157166-","A157167-","A157168-","C157169-","G157170-","C157171-","C157172-","A157173-","T157174-","C157175-","A157176-","T157177-","G157178-","A157179-","A157180-","T157181-","A157182-","G157183-","C157184-","A157185-","G157186-","T157187-","G157188-","A157189-","A157190-","T157191-","T157192-","A157193-","A157194-","T157195-","T157196-","G157197-","C157198-","T157199-","G157200-","T157201-","T157202-","A157203-","T157204-","T157205-","A157206-","T157207-","G157208-","G157209-","A157210-","T157211-","T157212-","T157213-","A157214-","G157215-","A157216-","A157217-","A157218-","T157219-","A157220-","G157221-","T157222-","G157223-","G157224-","A157225-","C157226-","G157227-","A157228-","T157229-","T157230-","T157231-","T157232-","G157233-","T157234-","G157235-","A157236-","T157237-","A157238-","T157239-","T157240-","A157241-","A157242-","T157243-","A157244-","T157245-","A157246-","G157247-","T157248-","T157249-","A157250-","T157251-","T157252-","A157253-","A157254-","T157255-","G157256-","A157257-","T157258-","G157259-","A157260-","A157261-","A157262-","G157263-","G157264-","A157265-","T157266-","A157267-","A157268-","A157269-","C157270-","G157271-","C157272-","T157273-","C157274-","A157275-","T157276-","A157277-","G157278-","A157279-","C157280-","T157281-","C157282-","A157283-","T157284-","C157285-","C157286-","T157287-","A157288-","T157289-","C157290-","T157291-","G157292-","G157293-","A157294-","G157295-","C157296-","C157297-","T157298-","C157299-","C157300-","G157301-","A157302-","A157303-","T157304-","A157305-","T157306-","T157307-","T157308-","T157309-","T157310-","T157311-","C157312-","C157313-","A157314-","T157315-","T157316-","C157317-","T157318-","G157319-","T157320-","T157321-","T157322-","T157323-","C157324-","C157325-","A157326-","A157327-","T157328-","A157329-","A157330-","T157331-","T157332-","T157333-","T157334-","A157335-","T157336-","C157337-","G157338-","A157339-","T157340-","T157341-","C157342-","T157343-","A157344-","A157345-","T157346-","G157347-","A157348-","A157349-","T157350-","A157351-","C157352-","G157353-","A157354-","A157355-","G157356-","T157357-","T157358-","A157359-","A157360-","T157361-","C157362-","T157363-","A157364-","A157365-","G157366-","T157367-","C157368-","A157369-","T157370-","T157371-","T157372-","A157373-","G157374-","A157375-","T157376-","T157377-","A157378-","T157379-","C157380-","A157381-","A157382-","A157383-","G157384-","T157385-","G157386-","T157387-","T157388-","A157389-","A157390-","C157391-","T157392-","A157393-","T157394-","T157395-","T157396-","G157397-","A157398-","T157399-","C157400-","G157401-","A157402-","T157403-","T157404-","A157405-","C157406-","A157407-","T157408-","T157409-","T157410-","A157411-","T157412-","G157413-","G157414-","G157415-","A157416-","T157417-","A157418-","C157419-","C157420-","T157421-","T157422-","T157423-","G157424-","A157425-","G157426-","C157427-","C157428-","T157429-","A157430-","A157431-","C157432-","T157433-","A157434-","A157435-","C157436-","G157437-","A157438-","T157439-","A157440-","A157441-","C157442-","G157443-","T157444-","G157445-","A157446-","A157447-","A157448-","T157449-","A157450-","T157451-","A157452-","T157453-","T157454-","C157455-","T157456-","T157457-","T157458-","C157459-","A157460-","A157461-","C157462-","C157463-","G157464-","C157465-","T157466-","G157467-","A157468-","T157469-","T157470-","T157471-","T157472-","T157473-","T157474-","T157475-","A157476-","C157477-","A157478-","A157479-","A157480-","T157481-","T157482-","G157483-","G157484-","A157485-","T157486-","C157487-","T157488-","G157489-","C157490-","C157491-","A157492-","T157493-","T157494-","A157495-","C157496-","T157497-","G157498-","A157499-","G157500-","T157501-","G157502-","C157503-","G157504-","A157505-","A157506-","A157507-","A157508-","A157509-","T157510-","A157511-","C157512-","A157513-","T157514-","A157515-","C157516-","T157517-","T157518-","A157519-","A157520-","A157521-","A157522-","A157523-","T157524-","C157525-","T157526-","T157527-","T157528-","G157529-","T157530-","T157531-","T157532-","T157533-","A157534-","G157535-","A157536-","A157537-","A157538-","C157539-","T157540-","G157541-","T157542-","A157543-","T157544-","C157545-","G157546-","A157547-","T157548-","T157549-","T157550-","C157551-","T157552-","A157553-","C157554-","A157555-","T157556-","A157557-","T157558-","A157559-","C157560-","G157561-","C157562-","T157563-","G157564-","A157565-","T157566-","A157567-","A157568-","A157569-","T157570-","A157571-","T157572-","A157573-","A157574-","T157575-","A157576-","A157577-","C157578-","A157579-","A157580-","G157581-","A157582-","A157583-","A157584-","A157585-","T157586-","A157587-","G157588-","A157589-","A157590-","T157591-","T157592-","A157593-","G157594-","C157595-","A157596-","T157597-","C157598-","G157599-","T157600-","T157601-","T157602-","A157603-","A157604-","C157605-","A157606-","C157607-","A157608-","A157609-","T157610-","A157611-","T157612-","T157613-","A157614-","C157615-","G157616-","A157617-","A157618-","A157619-","T157620-","A157621-","T157622-","T157623-","T157624-","T157625-","G157626-","A157627-","G157628-","A157629-","C157630-","T157631-","C157632-","A157633-","T157634-","C157635-","A157636-","A157637-","C157638-","A157639-","A157640-","T157641-","G157642-","A157643-","A157644-","A157645-","A157646-","C157647-","T157648-","T157649-","T157650-","A157651-","A157652-","A157653-","T157654-","A157655-","C157656-","T157657-","T157658-","A157659-","A157660-","C157661-","A157662-","G157663-","A157664-","G157665-","G157666-","A157667-","A157668-","T157669-","C157670-","A157671-","A157672-","T157673-","G157674-","A157675-","T157676-","A157677-","A157678-","A157679-","A157680-","A157681-","T157682-","T157683-","T157684-","T157685-","A157686-","A157687-","G157688-","C157689-","G157690-","A157691-","T157692-","G157693-","A157694-","T157695-","A157696-","T157697-","G157698-","T157699-","T157700-","A157701-","T157702-","A157703-","T157704-","A157705-","T157706-","A157707-","A157708-","A157709-","A157710-","A157711-","A157712-","T157713-","G157714-","A157715-","G157716-","G157717-","A157718-","T157719-","T157720-","T157721-","C157722-","A157723-","C157724-","C157725-","C157726-","C157727-","A157728-","C157729-","T157730-","G157731-","A157732-","T157733-","T157734-","C157735-","T157736-","C157737-","A157738-","T157739-","T157740-","A157741-","A157742-","A157743-","T157744-","G157745-","G157746-","T157747-","T157748-","A157749-","G157750-","A157751-","G157752-","A157753-","G157754-","T157755-","A157756-","C157757-","A157758-","C157759-","C157760-","A157761-","A157762-","C157763-","C157764-","A157765-","T157766-","G157767-","T157768-","A157769-","C157770-","C157771-","G157772-","T157773-","C157774-","G157775-","A157776-","G157777-","T157778-","T157779-","A157780-","C157781-","T157782-","T157783-","A157784-","G157785-","A157786-","T157787-","G157788-","C157789-","C157790-","T157791-","C157792-","A157793-","G157794-","A157795-","A157796-","T157797-","A157798-","T157799-","C157800-","A157801-","T157802-","T157803-","T157804-","C157805-","T157806-","T157807-","T157808-","C157809-","C157810-","C157811-","C157812-","A157813-","C157814-","A157815-","A157816-","G157817-","T157818-","T157819-","A157820-","T157821-","A157822-","A157823-","A157824-","A157825-","T157826-","C157827-","A157828-","C157829-","T157830-","T157831-","T157832-","A157833-","T157834-","A157835-","G157836-","T157837-","C157838-","A157839-","T157840-","C157841-","G157842-","A157843-","C157844-","T157845-","G157846-","G157847-","T157848-","T157849-","A157850-","G157851-","T157852-","T157853-","C157854-","A157855-","A157856-","T157857-","C157858-","T157859-","A157860-","C157861-","G157862-","A157863-","A157864-","T157865-","G157866-","T157867-","A157868-","T157869-","A157870-","A157871-","C157872-","A157873-","T157874-","T157875-","C157876-","T157877-","T157878-","A157879-","A157880-","A157881-","C157882-","A157883-","A157884-","T157885-","A157886-","T157887-","A157888-","G157889-","C157890-","A157891-","T157892-","T157893-","C157894-","T157895-","T157896-","G157897-","G157898-","A157899-","T157900-","A157901-","A157902-","A157903-","T157904-","C157905-","A157906-","T157907-","T157908-","T157909-","C157910-","C157911-","T157912-","A157913-","G157914-","A157915-","T157916-","A157917-","C157918-","C157919-","A157920-","T157921-","A157922-","T157923-","C157924-","A157925-","T157926-","C157927-","G157928-","A157929-","G157930-","T157931-","T157932-","G157933-","A157934-","T157935-","A157936-","T157937-","C157938-","T157939-","A157940-","T157941-","C157942-","G157943-","G157944-","T157945-","A157946-","T157947-","A157948-","A157949-","G157950-","T157951-","A157952-","A157953-","T157954-","T157955-","C157956-","A157957-","C157958-","A157959-","T157960-","G157961-","A157962-","T157963-","A157964-","A157965-","G157966-","A157967-","T157968-","T157969-","T157970-","C157971-","C157972-","A157973-","T157974-","A157975-","A157976-","A157977-","C157978-","T157979-","G157980-","C157981-","T157982-","A157983-","C157984-","A157985-","A157986-","T157987-","C157988-","A157989-","T157990-","A157991-","A157992-","A157993-","A157994-","A157995-","A157996-","A157997-","T157998-","T157999-","C158000-","A158001-","T158002-","G158003-","G158004-","G158005-","A158006-","A158007-","A158008-","T158009-","G158010-","A158011-","T158012-","A158013-","T158014-","C158015-","T158016-","T158017-","C158018-","A158019-","C158020-","G158021-","T158022-","A158023-","G158024-","A158025-","T158026-","A158027-","T158028-","A158029-","G158030-","G158031-","T158032-","G158033-","T158034-","A158035-","G158036-","T158037-","T158038-","T158039-","C158040-","G158041-","C158042-","A158043-","G158044-","T158045-","G158046-","A158047-","C158048-","C158049-","G158050-","T158051-","C158052-","C158053-","T158054-","G158055-","G158056-","A158057-","T158058-","A158059-","A158060-","T158061-","A158062-","T158063-","T158064-","A158065-","T158066-","C158067-","T158068-","A158069-","T158070-","A158071-","T158072-","G158073-","A158074-","T158075-","G158076-","G158077-","G158078-","T158079-","G158080-","G158081-","A158082-","T158083-","A158084-","T158085-","G158086-","A158087-","T158088-","C158089-","A158090-","G158091-","T158092-","C158093-","C158094-","C158095-","T158096-","G158097-","T158098-","A158099-","T158100-","A158101-","G158102-","A158103-","A158104-","G158105-","T158106-","T158107-","C158108-","A158109-","A158110-","A158111-","G158112-","G158113-","T158114-","T158115-","A158116-","T158117-","A158118-","G158119-","C158120-","G158121-","T158122-","A158123-","C158124-","A158125-","A158126-","T158127-","A158128-","C158129-","A158130-","T158131-","G158132-","T158133-","A158134-","C158135-","T158136-","A158137-","A158138-","T158139-","T158140-","C158141-","T158142-","T158143-","G158144-","G158145-","A158146-","T158147-","A158148-","T158149-","A158150-","T158151-","G158152-","A158153-","T158154-","A158155-","T158156-","A158157-","C158158-","C158159-","A158160-","G158161-","A158162-","G158163-","C158164-","T158165-","A158166-","A158167-","A158168-","A158169-","T158171-","A158172-","T158173-","C158174-","C158175-","T158176-","C158177-","G158178-","T158179-","T158180-","C158181-","T158182-","A158183-","A158184-","T158185-","T158186-","G158187-","C158188-","G158189-","G158190-","A158191-","G158192-","G158193-","A158194-","G158195-","T158196-","T158197-","G158198-","C158199-","C158200-","A158201-","A158202-","T158203-","G158204-","A158205-","C158206-","G158207-","A158208-","A158209-","T158210-","A158211-","C158212-","A158213-","T158214-","T158215-","T158216-","A158217-","T158218-","T158219-","G158220-","T158221-","A158222-","T158223-","A158224-","G158225-","G158226-","C158227-","G158228-","G158229-","T158230-","A158231-","T158232-","A158233-","C158234-","G158235-","C158236-","G158237-","A158238-","T158239-","C158240-","A158241-","G158242-","G158243-","A158244-","G158245-","T158246-","C158247-","A158248-","T158249-","C158250-","G158251-","T158252-","T158253-","G158254-","A158255-","T158256-","A158257-","T158258-","C158259-","T158260-","A158261-","G158262-","T158263-","A158264-","T158265-","C158266-","G158267-","A158268-","T158269-","A158270-","G158271-","A158272-","T158273-","G158274-","G158275-","A158276-","A158277-","G158278-","C158279-","C158280-","A158281-","T158282-","C158283-","A158284-","A158285-","A158286-","A158287-","C158288-","C158289-","A158290-","T158291-","A158292-","T158293-","T158294-","G158295-","G158296-","C158297-","A158298-","G158299-","A158300-","A158301-","G158302-","T158303-","A158304-","T158305-","G158306-","C158307-","T158308-","A158309-","A158310-","A158311-","A158312-","T158313-","G158314-","T158315-","G158316-","C158317-","G158318-","A158319-","A158320-","C158321-","C158322-","A158323-","A158324-","A158325-","A158326-","T158327-","G158328-","T158329-","G158330-","A158331-","T158332-","A158333-","T158334-","G158335-","G158336-","G158337-","G158338-","T158339-","T158340-","G158341-","C158342-","G158343-","A158344-","T158345-","T158346-","T158347-","T158348-","A158349-","A158350-","A158351-","C158352-","G158353-","G158354-","A158355-","T158356-","T158357-","A158358-","A158359-","T158360-","A158361-","T158362-","A158363-","T158364-","G158365-","T158366-","C158367-","A158368-","T158369-","A158370-","G158371-","G158372-","T158373-","G158374-","G158375-","A158376-","G158377-","T158378-","C158379-","G158380-","T158381-","T158382-","A158383-","A158384-","A158385-","G158386-","G158387-","T158388-","G158389-","A158390-","C158391-","A158392-","C158393-","A158394-","C158395-","A158396-","T158397-","G158398-","T158399-","A158400-","C158401-","C158402-","G158403-","A158404-","C158405-","G158406-","C158407-","A158408-","C158409-","T158410-","A158411-","G158412-","A158413-","G158414-","A158415-","G158416-","T158417-","T158418-","T158419-","A158420-","T158421-","C158422-","A158423-","G158424-","A158425-","A158426-","G158427-","A158428-","T158429-","G158430-","G158431-","A158432-","T158433-","G158434-","G158435-","A158436-","T158437-","G158438-","A158439-","A158440-","T158441-","C158442-","A158443-","T158444-","C158445-","A158446-","A158447-","C158448-","G158449-","T158450-","C158451-","T158452-","T158453-","C158454-","C158455-","A158456-","A158457-","T158458-","A158459-","A158460-","A158461-","A158462-","A158463-","T158464-","G158465-","T158466-","C158467-","C158468-","A158469-","A158470-","T158471-","A158472-","T158473-","G158474-","T158475-","C158476-","G158477-","A158478-","C158479-","G158480-","A158481-","T158482-","T158483-","G158484-","T158485-","T158486-","C158487-","A158488-","T158489-","G158490-","C158491-","T158492-","G158493-","G158494-","A158495-","A158496-","A158497-","G158498-","A158499-","T158500-","T158501-","T158502-","A158503-","T158504-","A158505-","T158506-","A158507-","T158508-","C158509-","T158510-","G158511-","G158512-","A158513-","G158514-","G158515-","T158516-","T158517-","A158518-","C158519-","A158520-","A158521-","C158522-","A158523-","A158524-","T158525-","A158526-","G158527-","T158528-","A158529-","G158530-","T158531-","G158532-","T158533-","A158534-","G158535-","T158536-","T158537-","A158538-","A158539-","T158540-","G158541-","T158542-","A158543-","A158544-","T158545-","A158546-","T158547-","C158548-","G158549-","A158550-","A158551-","T158552-","C158553-","T158554-","A158555-","G158556-","T158557-","C158558-","C158559-","T158560-","T158561-","A158562-","G158563-","C158564-","T158565-","A158566-","T158567-","A158568-","A158569-","T158570-","C158571-","C158572-","G158573-","A158574-","T158575-","A158576-","T158577-","A158578-","T158579-","G158580-","A158581-","T158582-","G158583-","A158584-","A158585-","T158586-","G158587-","G158588-","A158589-","C158590-","C158591-","A158592-","A158593-","A158594-","T158595-","T158596-","A158597-","T158598-","C158599-","A158600-","T158601-","C158602-","A158603-","T158604-","T158605-","A158606-","A158607-","A158608-","T158609-","A158610-","T158611-","T158612-","C158613-","C158614-","T158615-","A158616-","G158617-","A158618-","A158619-","T158620-","T158621-","A158622-","A158623-","T158624-","C158625-","C158626-","T158627-","G158628-","C158629-","T158630-","C158631-","T158632-","A158633-","T158634-","T158751G","G160043-","C160057A","A160270G","C161356T","A161579G","T161591C","T162384C","G162388A","C162447T","T162852A","A163207-","A163208-","C163209-","T163210-","A163211-","A163212-","C163213-","T163214-","C163256T","A163886G","G164849A","C166006T","C166196T","C166309A","T166712-","G167029A","C168226T","C168466A","C169125T","G169672A","A169769-","A169771-","A169773-","T169774-","T169792-","G170918-","C170999T","T172063-","A172550G","C172644T","C172671T","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","G173363T","G173436A","C173474T","A173501-","T173502-","T173745-","A174044T","C174102A","C174146T","G174183T","G174537-","A174538-","T174539-","G174540-","A174541-","A174542-","T174855C","G177853A","A178328-","C178702T","C179366T","A180163G","T180435A","A180548G","C180578T","A181114-","T181115-","T181116-","C181117-","C181118-","T181119-","T181120-","A181121-","T181122-","T181233C","C181351T","C181648A","A181790G","G181872A","A182356T","T182899C","C183555-","T183556-","A183557-","T184979C","C186840T","G187145A","T187207-","C187533A","T187775-","G187896T","A188871G","C189206T","C189609T","T189744-","A189896G","A190198-","C190199-","T191134C","A192435-","A192436-","G192437-","T192438-","C192439-","A192440-","T192441-","A192442-","A192443-","G192444-","T192445-","T192446-","A192447-","G192448-","T192449-","T192450-","A192451-","A192452-","G192453-","T192454-","C192455-","A192456-","T192457-","A192458-","A192459-","G192460-","T192461-","T192462-","A192463-","G192464-","T192465-","T192466-","A192467-","A192468-","G192469-","T192470-","T192471-","A192472-","T192473-","A192474-","A192475-","G192476-","T192477-","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-","A192490-","A192491-","G192492-","T192493-","T192494-","A192495-","G192496-","T192497-","T192498-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","C193168T","G194067A","G194551A","A194656G","G194969-","T194970-","C194971-","T195901C","C196461T","G196580T","A196608-","A196609-","A196610-","A196611-","A196612-","A196613-","A196614-","C196735T","A197082G"],"OPG002":["V172-"],"OPG002_dup":["V172-"],"OPG003":["A189V","D489N"],"OPG005":["S3F"],"OPG021":["S219L"],"OPG023":["M109I","S258L","C304R","A426T","L602I"],"OPG027":["I47V","V126I"],"OPG029":["D153-","D154-"],"OPG031":["T80M","C241Y","G258-"],"OPG037":["C144Y"],"OPG039":["C279Y"],"OPG044":["V63A","T109A"],"OPG065":["A17T","H61N"],"OPG068":["P251S"],"OPG070":["H205Y"],"OPG072":["V10I"],"OPG076":["S20N"],"OPG080":["L521P","P582H"],"OPG085":["S79T"],"OPG089":["D303E"],"OPG091":["V62I","S73N"],"OPG092":["I244N"],"OPG108":["T111I"],"OPG109":["R364S","A630T"],"OPG113":["V537I"],"OPG117":["D454N"],"OPG120":["A19T"],"OPG123":["I172T","A313T","C436Y"],"OPG125":["E111D"],"OPG130":["A63V","L270I"],"OPG133":["F594S"],"OPG134":["E226D"],"OPG136":["A229T","D267N","F283Y"],"OPG144":["T184I"],"OPG145":["I249V"],"OPG151":["D6V","N282D"],"OPG154":["R74H"],"OPG156":["I261M"],"OPG157":["Q61-"],"OPG160":["P2S"],"OPG163":["V46A"],"OPG164":["V228-"],"OPG165":["D106N"],"OPG172":["A125V"],"OPG180":["L555-"],"OPG181":["L85M","S127Y"],"OPG188":["V265I","S419R"],"OPG189":["K185R","R506H"],"OPG191":["P50Q"],"OPG192":["G100E"],"OPG197":["M1I"],"OPG200":["E134G"],"OPG205":["R733Q"],"OPG208":["A34V","T300A"],"OPG209":["I11V","L21F"],"OPG210":["A98D","V173I","N334I","V515A","L734-"]},"labels":{"aa":"OPG002: V172-; OPG002_dup: V172-; OPG003: A189V, D489N; OPG005: S3F; OPG021: S219L; OPG023: M109I, S258L, C304R, A426T, L602I; OPG027: I47V, V126I; OPG029: D153-, D154-; OPG031: T80M, C241Y, G258-; OPG037: C144Y; OPG039: C279Y; OPG044: V63A, T109A; OPG065: A17T, H61N; OPG068: P251S; OPG070: H205Y; OPG072: V10I; OPG076: S20N; OPG080: L521P, P582H; OPG085: S79T; OPG089: D303E; OPG091: V62I, S73N; OPG092: I244N; OPG108: T111I; OPG109: R364S, A630T; OPG113: V537I; OPG117: D454N; OPG120: A19T; OPG123: I172T, A313T, C436Y; OPG125: E111D; OPG130: A63V, L270I; OPG133: F594S; OPG134: E226D; OPG136: A229T, D267N, F283Y; OPG144: T184I; OPG145: I249V; OPG151: D6V, N282D; OPG154: R74H; OPG156: I261M; OPG157: Q61-; OPG160: P2S; OPG163: V46A; OPG164: V228-; OPG165: D106N; OPG172: A125V; OPG180: L555-; OPG181: L85M, S127Y; OPG188: V265I, S419R; OPG189: K185R, R506H; OPG191: P50Q; OPG192: G100E; OPG197: M1I; OPG200: E134G; OPG205: R733Q; OPG208: A34V, T300A; OPG209: I11V, L21F; OPG210: A98D, V173I, N334I, V515A, L734-","clade":"clade I"}},"children":[{"name":"JX878417","node_attrs":{"div":292,"accession":"JX878417","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878417/2006-12-14"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 07-0104"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-12-14"}},"branch_attrs":{"mutations":{"nuc":["T622-","C6615-","C13298T","A13302-","C13303-","C13304-","G13307-","A13308-","A13312T","A13313T","G13314T","C13316T","T13317A","G16147A","G23664T","T29805C","G31718A","C39731T","G47297T","C47929T","A49211G","C55169-","G59736A","A59910G","T70366C","T70958G","A71178-","C73040T","G87098T","C91509T","G91737A","C110159A","G117146A","G122405A","A142313G","C143414T","G143417C","T143419A","C143420-","A143421-","T143422-","G143423-","A143424-","A143425-","C143426-","C146214T","C148324A","T151060C","C159159T","C168295T","C169752T","C169770-","A169777-","G169778-","A169779-","A169780-","G169781-","A169782-","T169783-","A169784-","T169785-","C169786-","A169787-","T169788-","G169789-","A169790-","A169791-","G169793-","A169794-","A169795-","A169796-","C175361T","C178926-","A178927-","C179289T","T180737A","G181232A","G189594A","G191870A","A192420-","T197076G"],"OPG015_dup":["A273T"],"OPG039":["P152Q"],"OPG047":["I464V"],"OPG074":["V653-"],"OPG089":["S365A"],"OPG109":["R784S"],"OPG112":["A88V"],"OPG113":["A3T"],"OPG143":["A304V"],"OPG163":["N38D"],"OPG164":["Q213*","D214Q","H215-","E216-","H217-"],"OPG170":["G189R"],"OPG197":["T28I","T34V","E37-","D38-","I39-","M40-","N41-","E42-","I43-"],"OPG204":["T277M"],"OPG209":["S74T"]},"labels":{"aa":"OPG015_dup: A273T; OPG039: P152Q; OPG047: I464V; OPG074: V653-; OPG089: S365A; OPG109: R784S; OPG112: A88V; OPG113: A3T; OPG143: A304V; OPG163: N38D; OPG164: Q213*, D214Q, H215-, E216-, H217-; OPG170: G189R; OPG197: T28I, T34V, E37-, D38-, I39-, M40-, N41-, E42-, I43-; OPG204: T277M; OPG209: S74T"}}},{"name":"NODE_0000003","node_attrs":{"div":258,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["A204C","G994A","G16141T","C72111T","-169792C","A179227-","G186944T","G188824A","C196216T","T197006G"],"OPG027":["F79L"],"OPG210":["E1863D"]},"labels":{"aa":"OPG027: F79L; OPG210: E1863D"}},"children":[{"name":"NODE_0000004","node_attrs":{"div":264,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G1861A","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A6226-","T6227-","T6228-","C6229-","T6230-","T6281-","T6937-","G94890A","G105321T","C118612T","C121306T","C136555-","A136556-","T136557-","C136558-","A136559-","T136560-","A136561-","T136562-","C136563-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","A144618G","-148336T","-173295T","-173296A","-173297T","-173298A","-173299T","-173300A","-173301T","-173302A","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T187042-","C195349T"],"OPG136":["A326T"],"OPG153":["D372-","D373-","D374-","D376-"]},"labels":{"aa":"OPG136: A326T; OPG153: D372-, D373-, D374-, D376-"}},"children":[{"name":"KJ642618","node_attrs":{"div":296,"accession":"KJ642618","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"Cameroon"},"strain_display":{"value":"Cameroon/KJ642618/1990-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"KJ642618"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"date":{"value":"1990-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["G2075A","A4350-","G4351-","A4352-","T4353-","G4354-","G4355-","A4356-","T4357-","T4358-","A4359-","A4360-","A4361-","T4362-","C4363-","G4364-","T4365-","G4366-","T4367-","A4368-","T4369-","T4370-","C4371-","A4372-","T4373-","C4374-","G4375-","T4376-","A4377-","T4378-","A4379-","G4380-","C4381-","A4382-","A4383-","T4384-","G4385-","T4386-","A4387-","A4388-","T4389-","G4390-","G4391-","A4392-","G4393-","A4394-","G4395-","T4396-","T4397-","A4398-","C4399-","C4400-","A4401-","C4402-","A4403-","T4404-","T4405-","T4406-","T4407-","A4408-","G4409-","T4410-","C4411-","G4412-","T4413-","T4414-","T4415-","A4416-","T4417-","T4418-","C4419-","A4420-","G4421-","A4422-","T4423-","C4424-","G4425-","C4426-","A4427-","G4428-","T4429-","G4430-","T4431-","T4432-","T4433-","A4434-","A4435-","T4436-","A4437-","A4438-","C4439-","T4440-","A4441-","A4442-","T4443-","T4444-","T4445-","A4446-","A4447-","A4448-","C4449-","A4450-","G4451-","A4452-","T4453-","G4454-","A4455-","G4456-","A4457-","T4458-","G4459-","A4460-","T4461-","A4462-","T4463-","A4464-","T4465-","C4466-","C4467-","A4468-","C4469-","A4470-","T4471-","C4472-","A4473-","A4474-","A4475-","G4476-","A4477-","A4478-","T4479-","G4480-","C4481-","G4482-","A4483-","G4484-","A4485-","T4486-","A4487-","C4488-","A4489-","T4490-","A4491-","T4492-","G4493-","A4494-","C4495-","A4496-","G4497-","A4498-","C4499-","A4500-","T4501-","T4502-","A4503-","T4504-","T4505-","G4506-","A4507-","C4508-","A4509-","G4510-","A4511-","A4512-","A4513-","T4514-","G4515-","T4516-","G4517-","A4518-","C4519-","C4520-","T4521-","T4522-","C4523-","A4524-","T4525-","T4526-","A4527-","T4528-","C4529-","A4530-","C4531-","C4532-","G4533-","T4534-","C4535-","G4536-","T4537-","C4538-","C4539-","A4540-","T4541-","A4542-","A4543-","A4544-","T4545-","G4546-","C4547-","G4548-","T4549-","T4550-","A4551-","G4552-","G4553-","T4554-","A4555-","C4556-","G4557-","T4558-","A4559-","C4560-","C4561-","A4562-","C4563-","A4564-","T4565-","A4566-","C4567-","T4568-","A4569-","T4570-","C4571-","G4572-","T4573-","T4574-","A4575-","A4576-","C4577-","G4578-","A4579-","T4580-","G4581-","C4582-","G4583-","C4584-","A4585-","C4586-","A4587-","A4588-","T4589-","C4590-","T4591-","C4592-","G4593-","T4594-","C4595-","C4596-","A4597-","T4598-","T4599-","T4600-","C4601-","A4602-","T4603-","C4604-","C4605-","A4606-","T4607-","C4608-","T4609-","T4610-","C4611-","A4612-","T4613-","A4614-","A4615-","T4616-","G4617-","A4618-","T4619-","T4620-","T4621-","A4622-","C4623-","T4624-","T4625-","T4626-","T4627-","T4628-","C4629-","A4630-","T4631-","A4632-","A4633-","T4634-","T4635-","A4636-","G4637-","A4638-","G4639-","A4640-","A4641-","A4642-","A4643-","A4644-","G4645-","A4646-","T4647-","C4648-","A4649-","A4650-","G4651-","G4652-","T4653-","A4654-","T4655-","A4656-","A4657-","A4658-","A4659-","A4660-","T4661-","T4662-","A4663-","G4664-","A4665-","A4666-","G4667-","T4668-","G4669-","T4670-","T4671-","A4672-","G4673-","A4674-","C4675-","T4676-","A4677-","T4678-","A4679-","A4680-","A4681-","C4682-","T4683-","A4684-","A4685-","C4686-","T4687-","T4688-","A4689-","T4690-","A4691-","A4692-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","A4807-","T4808-","T4809-","A4810-","A4811-","C4812-","T4813-","C4814-","A4815-","T4816-","T4817-","T4818-","C4819-","A4820-","A4821-","G4822-","A4823-","A4824-","A4825-","G4826-","G4827-","T4828-","G4829-","G4830-","G4831-","T4832-","G4833-","G4834-","A4835-","G4836-","A4837-","G4838-","A4839-","A4840-","C4841-","T4842-","C4843-","T4844-","A4845-","T4846-","A4847-","T4848-","G4849-","A4850-","C4851-","A4852-","G4853-","C4854-","T4855-","T4856-","G4857-","T4858-","G4859-","A4860-","A4861-","A4862-","C4863-","A4864-","A4865-","T4866-","T4867-","A4868-","G4869-","A4870-","T4871-","C4872-","C4873-","C4874-","T4875-","A4876-","A4877-","T4878-","T4879-","T4880-","C4881-","T4882-","A4883-","A4884-","T4885-","G4886-","G4887-","A4888-","A4889-","G4890-","T4891-","T4892-","T4893-","T4894-","G4895-","A4896-","T4897-","A4898-","G4899-","G4900-","A4901-","G4902-","A4903-","T4904-","T4905-","G4906-","T4907-","C4908-","A4909-","T4910-","C4911-","A4912-","G4913-","T4914-","T4915-","G4916-","A4917-","T4918-","A4919-","C4920-","A4921-","T4922-","T4923-","G4924-","T4925-","T4926-","T4927-","A4928-","T4929-","T4930-","A4931-","T4932-","C4933-","T4934-","C4935-","A4936-","T4937-","C4938-","T4939-","A4940-","T4941-","T4942-","A4943-","G4944-","A4945-","G4946-","C4947-","A4948-","C4949-","G4950-","T4951-","C4952-","T4953-","G4954-","T4955-","T4956-","T4957-","A4958-","G4959-","A4960-","G4961-","C4962-","T4963-","T4964-","T4965-","A4966-","G4967-","T4968-","G4969-","A4970-","C4971-","C4972-","T4973-","G4974-","C4975-","T4976-","C4977-","G4978-","G4979-","T4980-","T4981-","A4982-","C4983-","T4984-","T4985-","C4986-","T4987-","G4988-","T4989-","G4990-","T4991-","A4992-","A4993-","A4994-","T4995-","C4996-","T4997-","T4998-","G4999-","A5000-","A5001-","T5002-","C5003-","C5004-","T5005-","T5006-","T5007-","A5008-","G5009-","T5010-","G5011-","A5012-","T5013-","A5014-","C5015-","A5016-","C5017-","T5018-","G5019-","T5020-","G5021-","T5022-","C5023-","A5024-","A5025-","A5026-","A5027-","C5028-","T5029-","G5030-","G5031-","A5032-","T5033-","G5034-","T5035-","T5036-","T5037-","A5038-","G5039-","A5040-","A5041-","T5042-","A5043-","C5044-","C5045-","T5046-","A5047-","T5048-","G5049-","T5050-","A5051-","G5052-","A5053-","A5054-","T5055-","A5056-","T5057-","G5058-","G5059-","G5060-","A5061-","A5062-","G5063-","C5064-","A5065-","T5066-","G5067-","C5068-","T5069-","T5070-","G5071-","T5072-","T5073-","T5074-","T5075-","T5076-","G5077-","T5078-","C5079-","T5080-","C5081-","T5082-","A5083-","T5084-","T5085-","A5086-","T5087-","A5088-","G5089-","A5090-","T5091-","T5092-","A5093-","A5094-","C5095-","T5096-","C5097-","A5098-","T5099-","A5100-","C5101-","A5102-","T5103-","G5104-","G5105-","T5106-","T5107-","G5108-","T5109-","A5110-","T5111-","T5112-","A5113-","T5114-","G5115-","A5116-","A5117-","T5118-","T5119-","T5120-","T5121-","C5122-","A5123-","T5124-","C5125-","T5126-","G5127-","C5128-","C5129-","T5130-","A5131-","A5132-","T5133-","G5134-","T5135-","A5136-","C5137-","T5138-","C5139-","C5140-","A5141-","A5142-","T5143-","T5144-","C5145-","T5146-","T5147-","G5148-","T5149-","T5150-","T5151-","A5152-","C5153-","A5154-","A5155-","T5156-","C5157-","A5158-","A5159-","T5160-","T5161-","A5162-","T5163-","A5164-","T5165-","A5166-","A5167-","T5168-","C5169-","A5170-","A5171-","A5172-","G5173-","A5174-","G5175-","T5176-","G5177-","A5178-","T5179-","G5180-","A5181-","T5182-","G5183-","C5184-","A5185-","T5186-","A5187-","C5188-","A5189-","C5190-","A5191-","T5192-","T5193-","A5194-","C5195-","A5196-","A5197-","A5198-","G5199-","T5200-","G5201-","A5202-","A5203-","T5204-","A5205-","A5206-","T5207-","C5208-","T5209-","A5210-","C5211-","C5212-","A5213-","T5214-","C5215-","A5216-","T5217-","A5218-","A5219-","A5220-","A5221-","T5222-","A5223-","C5224-","T5225-","T5226-","G5227-","A5228-","T5229-","A5230-","C5231-","A5232-","G5233-","A5234-","G5235-","C5236-","T5237-","T5238-","T5239-","A5240-","T5241-","C5242-","A5243-","C5244-","A5245-","T5246-","C5247-","A5248-","T5249-","G5250-","G5251-","T5252-","T5253-","T5254-","T5255-","C5256-","A5257-","A5258-","T5259-","T5260-","G5261-","T5262-","A5263-","T5264-","T5265-","A5266-","T5267-","T5268-","A5269-","A5270-","G5271-","T5272-","A5273-","T5274-","A5275-","G5276-","C5277-","T5278-","A5279-","A5280-","T5281-","T5282-","T5283-","T5284-","A5285-","T5286-","A5287-","C5288-","A5289-","G5290-","T5291-","C5292-","A5293-","A5294-","T5295-","A5296-","G5297-","A5298-","C5299-","A5300-","A5301-","T5302-","G5303-","G5304-","T5305-","T5306-","C5307-","T5308-","C5309-","T5310-","A5311-","A5312-","G5313-","C5314-","A5315-","A5316-","T5317-","A5318-","T5319-","T5320-","T5321-","C5322-","T5323-","A5324-","A5325-","T5326-","A5327-","T5328-","T5329-","T5330-","T5331-","A5332-","A5333-","G5334-","A5335-","T5336-","G5337-","T5338-","G5339-","C5340-","T5341-","T5342-","C5343-","C5344-","C5345-","T5346-","A5347-","C5348-","G5349-","G5350-","G5351-","C5352-","G5353-","A5354-","T5355-","G5356-","A5357-","C5358-","A5359-","G5360-","A5361-","T5362-","C5363-","C5364-","C5365-","C5366-","T5367-","A5368-","T5369-","C5370-","C5371-","A5372-","C5373-","G5374-","G5375-","C5376-","C5377-","A5378-","C5379-","G5380-","T5381-","C5382-","A5383-","A5384-","G5385-","A5386-","C5387-","A5388-","T5389-","G5390-","T5391-","A5392-","T5393-","A5394-","T5395-","C5396-","C5397-","A5398-","T5399-","T5400-","A5401-","C5402-","T5403-","C5404-","A5405-","T5406-","T5407-","A5408-","C5409-","T5410-","G5411-","C5412-","G5413-","T5414-","T5415-","G5416-","A5417-","C5418-","A5419-","T5420-","T5421-","T5422-","G5423-","C5424-","T5425-","C5426-","C5427-","A5428-","T5429-","T5430-","T5431-","T5432-","C5433-","T5434-","A5435-","A5436-","T5437-","A5438-","G5439-","C5440-","C5441-","A5442-","T5443-","G5444-","A5445-","T5446-","A5447-","C5448-","T5449-","A5450-","A5451-","A5452-","T5453-","C5454-","T5455-","A5456-","T5457-","A5458-","T5459-","A5460-","A5461-","C5462-","C5463-","T5464-","G5465-","C5466-","A5467-","T5468-","A5469-","G5470-","A5471-","T5472-","A5473-","G5474-","C5475-","G5476-","C5477-","G5478-","A5479-","T5480-","A5481-","A5482-","A5483-","G5484-","C5485-","A5486-","A5487-","G5488-","G5489-","T5490-","C5491-","C5492-","T5493-","T5494-","C5495-","C5496-","A5497-","C5498-","C5499-","A5500-","G5501-","C5502-","A5503-","T5504-","C5505-","T5506-","A5507-","G5508-","T5509-","T5510-","G5511-","A5512-","T5513-","T5514-","G5515-","A5516-","T5517-","A5518-","T5519-","C5520-","T5521-","T5522-","C5523-","A5524-","A5525-","T5526-","A5527-","T5528-","A5529-","T5530-","G5531-","G5532-","G5533-","A5534-","T5535-","A5536-","C5537-","A5538-","A5539-","A5540-","G5541-","C5542-","T5543-","T5544-","A5545-","T5546-","A5547-","A5548-","A5549-","T5550-","T5551-","T5552-","C5553-","T5554-","A5555-","A5556-","T5557-","A5558-","C5559-","T5560-","G5561-","T5562-","G5563-","G5564-","G5565-","T5566-","T5567-","C5568-","A5569-","T5570-","C5571-","T5572-","A5573-","C5574-","A5575-","A5576-","G5577-","G5578-","A5579-","A5580-","T5581-","C5582-","C5583-","C5584-","C5585-","T5586-","A5587-","G5588-","T5589-","A5590-","T5591-","A5592-","C5593-","T5594-","G5595-","A5596-","A5597-","T5598-","T5599-","A5600-","T5601-","T5602-","T5603-","T5604-","A5605-","T5606-","A5607-","T5608-","A5609-","G5610-","A5611-","T5612-","C5613-","T5614-","A5615-","A5616-","T5617-","T5618-","T5619-","A5620-","A5621-","C5622-","A5623-","T5624-","C5625-","A5626-","T5627-","T5628-","T5629-","T5630-","C5631-","A5632-","T5633-","C5634-","T5635-","G5636-","G5637-","G5638-","A5639-","T5640-","A5641-","C5642-","C5643-","A5644-","C5645-","A5646-","A5647-","T5648-","T5649-","C5650-","A5651-","A5652-","A5653-","A5654-","T5655-","A5656-","A5657-","A5658-","C5659-","T5660-","C5661-","A5662-","A5663-","C5664-","A5665-","A5666-","C5667-","A5668-","C5669-","T5670-","A5671-","C5672-","T5673-","T5674-","T5675-","C5676-","C5677-","T5678-","T5679-","T5680-","T5681-","T5682-","A5683-","C5684-","A5685-","T5686-","A5687-","T5688-","T5689-","C5690-","C5691-","C5692-","C5693-","T5694-","A5695-","A5696-","A5697-","A5698-","T5699-","A5700-","G5701-","G5702-","C5703-","A5704-","T5705-","T5706-","C5707-","A5708-","A5709-","G5710-","C5711-","A5712-","T5713-","T5714-","C5715-","T5716-","A5717-","T5718-","T5719-","T5720-","T5721-","A5722-","T5723-","A5724-","T5725-","A5726-","T5727-","T5728-","A5729-","C5730-","A5731-","G5732-","C5733-","C5734-","C5735-","C5736-","A5737-","T5738-","G5739-","A5740-","T5741-","C5742-","T5743-","A5744-","C5745-","C5746-","A5747-","T5748-","A5749-","A5750-","A5751-","A5752-","T5753-","C5754-","A5755-","A5756-","C5757-","A5758-","A5759-","T5760-","G5761-","T5762-","C5763-","T5764-","A5765-","T5766-","T5767-","T5768-","C5769-","T5770-","A5771-","C5772-","A5773-","T5774-","A5775-","T5776-","G5777-","C5778-","A5779-","T5780-","T5781-","A5782-","G5783-","A5784-","T5785-","A5786-","G5787-","A5788-","T5789-","A5790-","G5791-","T5792-","A5793-","A5794-","A5795-","G5796-","T5797-","A5798-","A5799-","G5800-","A5801-","G5802-","A5803-","T5804-","C5805-","T5806-","T5807-","G5808-","T5809-","A5810-","C5811-","A5812-","G5813-","A5814-","A5815-","T5816-","T5817-","A5818-","C5819-","A5820-","A5821-","T5822-","T5823-","C5824-","T5825-","T5826-","A5827-","A5828-","T5829-","A5830-","A5831-","T5832-","T5833-","A5834-","T5835-","A5836-","G5837-","A5838-","G5839-","A5840-","A5841-","A5842-","A5843-","T5844-","A5845-","T5846-","C5847-","T5848-","T5849-","C5850-","C5851-","A5852-","T5853-","A5854-","T5855-","A5856-","A5857-","T5858-","T5859-","C5860-","T5861-","T5862-","T5863-","G5864-","A5865-","C5866-","A5867-","C5868-","T5869-","A5870-","A5871-","T5872-","G5873-","C5874-","A5875-","G5876-","A5877-","T5878-","A5879-","T5880-","A5881-","A5882-","T5883-","A5884-","T5885-","C5886-","T5887-","T5888-","T5889-","A5890-","T5891-","A5892-","T5893-","G5894-","T5895-","A5896-","A5897-","T5898-","A5899-","T5900-","A5901-","T5902-","G5903-","C5904-","A5905-","A5906-","A5907-","C5908-","A5909-","G5910-","T5911-","C5912-","T5913-","A5914-","T5915-","C5916-","T5917-","A5918-","C5919-","T5920-","A5921-","T5922-","A5923-","T5924-","A5925-","C5926-","T5927-","G5928-","A5929-","T5930-","C5931-","A5932-","A5933-","T5934-","A5935-","T5936-","T5937-","A5938-","T5939-","C5940-","T5941-","C5942-","T5943-","A5944-","T5945-","G5946-","A5947-","A5948-","T5949-","C5950-","C5951-","T5952-","A5953-","A5954-","A5955-","A5956-","T5957-","A5958-","A5959-","T5960-","C5961-","A5962-","T5963-","A5964-","C5965-","A5966-","G5967-","A5968-","A5969-","C5970-","A5971-","T5972-","C5973-","T5974-","A5975-","C5976-","A5977-","G5978-","G5979-","A5980-","T5981-","C5982-","A5983-","C5984-","A5985-","A5986-","A5987-","T5988-","T5989-","G5990-","G5991-","T5992-","T5993-","C5994-","A5995-","A5996-","G5997-","G5998-","A5999-","G6000-","A6001-","A6002-","A6003-","T6004-","C6005-","T6006-","A6007-","T6008-","C6009-","A6010-","A6011-","A6012-","T6013-","A6014-","T6015-","T6016-","T6017-","T6018-","C6019-","C6020-","T6021-","G6022-","T6023-","C6024-","A6025-","A6026-","C6027-","A6028-","A6029-","C6030-","T6031-","G6032-","G6033-","T6034-","T6035-","C6036-","T6037-","A6038-","G6039-","A6040-","A6041-","C6042-","A6043-","T6044-","A6045-","A6046-","C6047-","A6048-","G6049-","T6050-","C6051-","A6052-","A6053-","C6054-","A6055-","C6056-","C6057-","T6058-","A6059-","A6060-","T6061-","C6062-","C6063-","A6064-","T6065-","G6066-","T6067-","T6068-","T6069-","T6070-","T6071-","T6072-","A6073-","T6074-","A6075-","G6076-","T6077-","C6078-","A6079-","T6080-","C6081-","T6082-","A6083-","C6084-","C6085-","A6086-","A6087-","A6088-","G6089-","A6090-","T6091-","A6092-","A6093-","T6094-","G6095-","A6096-","C6097-","C6098-","A6099-","A6100-","A6101-","G6102-","A6103-","T6104-","C6105-","G6106-","A6107-","G6108-","G6109-","T6110-","C6111-","G6112-","T6113-","C6114-","G6115-","T6116-","G6117-","A6118-","A6119-","A6120-","C6121-","T6122-","G6123-","C6124-","T6125-","C6126-","A6127-","T6128-","C6129-","G6130-","A6131-","C6132-","A6133-","G6134-","C6135-","C6136-","A6137-","T6138-","G6139-","A6140-","A6141-","A6142-","T6143-","C6144-","T6145-","G6146-","C6147-","C6148-","G6149-","A6150-","C6151-","T6152-","C6153-","C6154-","A6155-","T6156-","G6157-","G6158-","C6159-","G6160-","C6161-","G6162-","A6163-","A6164-","T6165-","C6166-","G6167-","C6168-","A6169-","C6170-","T6171-","G6172-","T6173-","C6174-","T6175-","T6176-","A6177-","T6178-","T6179-","C6180-","G6181-","C6182-","C6183-","A6184-","T6185-","T6186-","G6187-","A6188-","T6189-","T6190-","T6191-","T6192-","C6193-","A6194-","T6195-","T6196-","T6197-","T6198-","T6199-","T6200-","A6201-","T6202-","A6203-","A6204-","T6205-","T6206-","A6207-","T6208-","G6209-","T6210-","A6211-","C6212-","A6213-","T6214-","G6215-","T6216-","T6217-","T6218-","T6219-","C6220-","C6221-","T6222-","T6223-","C6224-","T6225-","C6231-","A6232-","A6233-","G6234-","A6235-","G6236-","T6237-","C6238-","T6239-","A6240-","C6241-","A6242-","A6243-","A6244-","A6245-","A6246-","T6247-","A6248-","T6249-","A6250-","T6251-","T6252-","T6253-","T6254-","T6255-","T6256-","C6257-","G6258-","A6259-","T6260-","A6261-","T6262-","C6263-","T6264-","A6265-","A6266-","G6267-","T6268-","A6269-","C6270-","T6271-","A6272-","A6273-","G6274-","T6275-","T6276-","T6277-","T6278-","T6279-","T6280-","A6282-","C6283-","T6284-","G6285-","T6286-","T6287-","T6288-","T6289-","T6290-","G6291-","T6292-","T6293-","A6294-","C6295-","T6296-","G6297-","T6298-","C6299-","T6300-","T6301-","C6302-","C6303-","A6304-","T6305-","T6306-","C6307-","T6308-","T6309-","C6310-","T6311-","A6312-","A6313-","C6314-","T6315-","A6316-","A6317-","A6318-","G6319-","A6320-","T6321-","C6322-","T6323-","G6324-","A6325-","G6326-","A6327-","T6328-","A6329-","A6330-","A6331-","T6332-","T6333-","A6334-","T6335-","A6336-","C6337-","A6338-","A6339-","T6340-","C6341-","T6342-","T6343-","C6344-","G6345-","C6346-","T6347-","A6348-","T6349-","C6350-","G6351-","A6352-","A6353-","C6354-","C6355-","A6356-","T6357-","T6358-","T6359-","T6360-","T6361-","G6362-","T6363-","A6364-","G6365-","T6366-","C6367-","T6368-","A6369-","A6370-","A6371-","G6372-","C6373-","C6374-","T6375-","G6376-","A6377-","A6378-","G6379-","T6380-","A6381-","A6382-","T6383-","T6384-","A6385-","A6386-","C6387-","C6388-","A6389-","A6390-","C6391-","T6392-","G6393-","T6394-","T6395-","T6396-","T6397-","T6398-","A6399-","T6400-","T6401-","A6402-","G6403-","T6404-","G6405-","G6406-","C6407-","T6408-","T6409-","T6410-","T6411-","T6412-","T6413-","C6414-","G6415-","A6416-","T6417-","C6418-","T6419-","A6420-","T6421-","C6422-","C6423-","T6424-","C6425-","G6426-","T6427-","C6428-","C6431-","T6432-","C6433-","A6434-","T6435-","C6436-","A6437-","T6438-","C6439-","C6440-","T6441-","T6442-","A6443-","T6444-","A6445-","T6446-","T6447-","A6448-","T6449-","T6450-","A6451-","T6452-","C6453-","A6454-","T6455-","T6456-","A6457-","T6458-","T6459-","A6460-","T6461-","C6462-","A6463-","T6464-","A6465-","G6466-","T6467-","C6468-","T6469-","A6470-","T6471-","T6472-","A6473-","A6474-","A6475-","C6476-","A6477-","C6478-","A6479-","A6480-","A6481-","T6482-","C6483-","A6484-","T6485-","C6486-","T6487-","A6488-","C6489-","G6490-","T6491-","T6492-","T6493-","A6494-","T6495-","A6496-","A6497-","C6498-","A6499-","A6500-","C6501-","A6502-","T6503-","T6504-","C6505-","T6506-","C6507-","A6508-","T6509-","T6510-","A6511-","T6512-","T6513-","A6514-","A6515-","T6516-","T6517-","A6518-","G6519-","T6520-","T6521-","C6522-","T6523-","G6524-","T6525-","A6526-","G6527-","A6528-","A6529-","T6530-","A6531-","T6532-","C6533-","T6534-","T6535-","T6536-","A6537-","A6538-","T6539-","A6540-","A6541-","T6542-","T6543-","T6544-","G6545-","G6546-","C6547-","T6548-","A6549-","T6550-","A6551-","C6552-","A6553-","T6554-","C6555-","T6556-","G6557-","T6558-","T6559-","C6560-","A6561-","A6562-","T6563-","A6564-","C6565-","T6566-","A6567-","T6568-","C6569-","T6570-","A6571-","T6572-","T6573-","G6574-","A6575-","T6576-","G6577-","A6578-","T6579-","T6580-","T6581-","C6582-","T6583-","T6584-","T6585-","T6586-","T6587-","T6588-","A6589-","A6590-","G6591-","A6592-","C6593-","T6594-","T6595-","A6596-","A6597-","A6598-","C6599-","T6600-","A6601-","G6602-","T6603-","T6604-","A6605-","T6606-","G6607-","G6608-","T6609-","A6610-","A6611-","T6612-","G6613-","A6614-","C6615-","G6616-","A6617-","T6618-","G6619-","A6620-","A6621-","A6622-","T6623-","C6624-","G6625-","A6626-","G6627-","T6628-","A6629-","G6630-","T6631-","A6632-","A6633-","C6634-","T6635-","T6636-","C6637-","T6638-","A6639-","A6640-","T6641-","A6642-","A6643-","A6644-","G6645-","A6646-","C6647-","T6648-","T6649-","G6650-","A6651-","T6652-","A6653-","T6654-","C6655-","A6656-","T6657-","T6658-","A6659-","T6660-","C6661-","A6662-","T6663-","A6664-","T6665-","G6666-","T6667-","T6668-","T6669-","G6670-","A6671-","T6672-","C6673-","G6674-","T6675-","C6676-","A6677-","T6678-","A6679-","G6680-","T6681-","T6682-","A6683-","A6684-","T6685-","A6686-","G6687-","T6688-","G6689-","T6690-","G6691-","G6692-","C6693-","T6694-","A6695-","A6696-","A6697-","T6698-","G6699-","G6700-","T6701-","A6702-","C6703-","T6704-","G6705-","T6706-","T6707-","A6708-","A6709-","T6710-","A6711-","A6712-","G6713-","T6714-","T6715-","T6716-","A6717-","T6718-","A6719-","G6720-","A6721-","C6722-","A6723-","A6724-","T6725-","A6726-","T6727-","C6728-","A6729-","T6730-","A6731-","G6732-","T6733-","A6734-","T6735-","T6736-","T6737-","T6738-","C6739-","T6740-","T6741-","T6742-","C6743-","C6744-","A6745-","G6746-","A6747-","A6748-","T6749-","T6750-","A6751-","G6752-","A6753-","T6754-","T6755-","A6756-","T6757-","T6758-","T6759-","T6760-","T6761-","T6762-","T6763-","A6764-","A6765-","A6766-","T6767-","A6768-","C6769-","T6770-","G6771-","A6772-","T6773-","C6774-","C6775-","T6776-","C6777-","A6778-","C6779-","A6780-","A6781-","T6782-","T6783-","C6784-","C6785-","G6786-","T6787-","G6788-","A6789-","T6790-","G6791-","T6792-","A6793-","G6794-","C6795-","A6796-","G6797-","T6798-","A6799-","G6800-","T6801-","T6802-","G6803-","G6804-","T6805-","G6806-","C6807-","A6808-","T6809-","G6810-","G6811-","T6812-","C6813-","T6814-","A6815-","T6816-","A6817-","T6818-","C6819-","G6820-","T6821-","T6822-","A6823-","A6824-","A6825-","A6826-","T6827-","G6828-","T6829-","A6830-","T6831-","C6832-","A6833-","T6834-","A6835-","T6836-","A6837-","T6838-","A6839-","A6840-","T6841-","A6842-","G6843-","T6844-","T6845-","T6846-","T6847-","C6848-","T6849-","G6850-","A6851-","C6852-","G6853-","T6854-","G6855-","G6856-","A6857-","G6858-","T6859-","A6860-","C6861-","A6862-","G6863-","A6864-","A6865-","T6866-","T6867-","T6868-","T6869-","C6870-","G6871-","A6872-","T6873-","T6874-","A6875-","A6876-","T6877-","G6878-","A6879-","G6880-","T6881-","T6882-","C6883-","A6884-","T6885-","G6886-","G6887-","T6888-","A6889-","A6890-","G6891-","G6892-","A6893-","A6894-","G6895-","G6896-","G6897-","C6898-","A6899-","A6900-","A6901-","T6902-","G6903-","T6904-","C6905-","T6906-","G6907-","T6908-","A6909-","T6910-","A6911-","T6912-","A6913-","A6914-","T6915-","A6916-","T6917-","A6918-","C6919-","A6920-","T6921-","A6922-","A6923-","G6924-","T6925-","T6926-","A6927-","A6928-","T6929-","A6930-","G6931-","T6932-","T6933-","T6934-","T6935-","T6936-","A6938-","T6939-","C6940-","A6941-","T6942-","A6943-","T6944-","T6945-","T6946-","T6947-","C6948-","T6949-","A6950-","A6951-","T6952-","A6953-","C6954-","C6955-","A6956-","T6957-","A6958-","A6959-","T6960-","A6961-","A6962-","A6963-","A6964-","A6965-","T6966-","T6967-","A6968-","T6969-","C6970-","A6971-","T6972-","T6973-","A6974-","T6975-","G6976-","T6977-","G6978-","T6979-","T6980-","T6981-","G6982-","T6983-","G6984-","T6985-","A6986-","G6987-","A8366C","G8599A","G10923A","T12181A","T15127-","C17933T","T18703C","C21073A","T29758C","C29763T","G33053A","A35238G","A38984G","G46402T","G47539A","C47904-","C47905-","G64207A","T66182C","G69898A","A88356G","G102985T","C109017T","C115292T","G133070A","A136512C","A136543-","T136544-","C136545-","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","C142360T","C145930-","G148718A","C152844T","C158803A","C159989T","C160938T","C166345A","G167529T","G169595A","-169769A","-169771A","-169772G","-169773A","-169774T","A173273-","A173274-","T173275-","A173276-","T173277-","A173278-","T173279-","A173280-","T173281-","A173282-","T173283-","A173284-","T173285-","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","C174599T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C192693T","C195135T"],"OPG002":["A226V"],"OPG002_dup":["A226V"],"OPG023":["Q660*"],"OPG031":["C299Y"],"OPG047":["D478N"],"OPG065":["R28S"],"OPG153":["D375-","D377-","D378-","Y386D"],"OPG187":["A106V"],"OPG191":["S62*"],"OPG193":["D66Y"],"OPG204":["A23V"]},"labels":{"aa":"OPG002: A226V; OPG002_dup: A226V; OPG023: Q660*; OPG031: C299Y; OPG047: D478N; OPG065: R28S; OPG153: D375-, D377-, D378-, Y386D; OPG187: A106V; OPG191: S62*; OPG193: D66Y; OPG204: A23V"}}},{"name":"NODE_0000005","node_attrs":{"div":288,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G8394T","C10147T","G11051A","G15606A","G18280A","G21146T","T32747C","G36045T","C39311G","A45542G","G84665A","A92711G","G114697T","G135808A","C136539G","C136542-","-140134A","-140135A","-140136C","-140137A","-140138A","-140139T","-140140T","-140141A","-140142T","C148484T","T148958C","C156205T","A156206C","-156210A","C169770-","C170542T","A172885-","-173286A","-173287T","-173288A","-173289T","-173290A","-173291T","-173292A","-173293T","-173294A","G173318-","G173595A","G176943A","C188468T","A188511G","C190447T","A190935-","T190984-","A190985-","G190986-","A190987-","A190988-","A192419-","A192420-","G192421-","T192422-","C192423-","A192424-","T192425-","A192426-","A192427-","G192428-","T192429-","T192430-","A192431-","G192432-","T192433-","T192434-"],"OPG016":["A13V","T176-"],"OPG023":["A617V"],"OPG037":["H430N"],"OPG055":["L347I"],"OPG133":["P334T"],"OPG159":["-124N","-125Y","-126N"],"OPG197":["T34-","D35-"],"OPG198":["H169Y"],"OPG205":["A430T"]},"labels":{"aa":"OPG016: A13V, T176-; OPG023: A617V; OPG037: H430N; OPG055: L347I; OPG133: P334T; OPG159: -124N, -125Y, -126N; OPG197: T34-, D35-; OPG198: H169Y; OPG205: A430T"}},"children":[{"name":"KJ642619","node_attrs":{"div":290,"accession":"KJ642619","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"Gabon"},"strain_display":{"value":"Gabon/KJ642619/1988-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"KJ642619"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"date":{"value":"1988-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["A24147T","T24148A"]}}},{"name":"OP498046","node_attrs":{"div":292,"accession":"OP498046","author":{"author":"Emmerich,P.,Bialonski,A.,Tomazatos,A.,Cadar,D.","value":"Emmerich,P.,Bialonski,A.,Tomazatos,A.,Cadar,D."},"country":{"value":"Gabon"},"strain_display":{"value":"Gabon/OP498046/1988-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"BNITM-Gabon1988"},"institution":{"value":"Bernhard Nocht Institute for Tropical Medicine, Arbovirology and Entomology"},"host":{"value":"Homo sapiens"},"date":{"value":"1988-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["G11865C","T24612C","C151380T","G171690A"],"OPG023":["L346V"],"OPG199":["D235N"]},"labels":{"aa":"OPG023: L346V; OPG199: D235N"}}}]}]},{"name":"NODE_0000006","node_attrs":{"div":270,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G40182A","C54569A","G56397T","C57678T","C87267T","C109535A","G122405A","A134326G","G145959A","G146433A","A165096G","C179226T","A179236G","G187305A"],"OPG057":["A5V"],"OPG072":["L34I"],"OPG143":["A304V"],"OPG170":["H116Y"]},"labels":{"aa":"OPG057: A5V; OPG072: L34I; OPG143: A304V; OPG170: H116Y"}},"children":[{"name":"KJ642612","node_attrs":{"div":292,"accession":"KJ642612","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/KJ642612/1986-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"KJ642612"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"date":{"value":"1986-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["G18301A","T29758C","C29763T","G31718A","T33822A","G35972T","G39173A","G53569A","G53953A","T77412A","T90138C","A91005G","G96915A","G107670A","C117896T","C128183A","-148336T","G150582T","T151256A","T151769C","-169769A","-169771A","-169772G","-169773A","-169774T","C176495T","C179136T","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","A179218G","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","A181253-","C181619T","T187676C","T187975-","A187976-","A190302G","G197006T"],"OPG047":["D478N"],"OPG054":["P9T"]},"labels":{"aa":"OPG047: D478N; OPG054: P9T"}}},{"name":"NODE_0000007","node_attrs":{"div":283,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T622-","C5340T","C8344A","C15209A","C21369A","T52086C","A71178-","C76021T","T82313C","G98856A","G122351A","G129583T","T150936C","G154730A","C169752T","C169770-","A169777-","G169778-","A169779-","A169780-","G169781-","A169782-","T169783-","A169784-","T169785-","C169786-","A169787-","T169788-","G169789-","A169790-","A169791-","C169792-","G169793-","A169794-","A169795-","A169796-","C171561T","-179227C","G191870A","A196593-"],"OPG015":["A273T"],"OPG015_dup":["A273T"],"OPG025":["S20I"],"OPG037":["M355I"],"OPG071":["N785D"],"OPG143":["A322V"],"OPG181":["A107T"],"OPG197":["T28I","T34V","E37-","D38-","I39-","M40-","N41-","E42-","I43-"],"OPG199":["P192S"]},"labels":{"aa":"OPG015: A273T; OPG015_dup: A273T; OPG025: S20I; OPG037: M355I; OPG071: N785D; OPG143: A322V; OPG181: A107T; OPG197: T28I, T34V, E37-, D38-, I39-, M40-, N41-, E42-, I43-; OPG199: P192S"}},"children":[{"name":"NODE_0000008","node_attrs":{"div":284,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C19745T"]}},"children":[{"name":"NC_003310","node_attrs":{"div":379,"accession":"NC_003310","author":{"author":"Senkevich,T.G.,Yutin,N.,Wolf,Y.I.,Koonin,E.V.,Moss,B.,Zmasek,C.M.,Knipe,D.M.,Pellett,P.E.,Scheuermann,R.H.,Shchelkunov,S.N.,Totmenin,A.V.,Babkin,I.V.,Safronov,P.F.,Ryazankina,O.I.,Petrov,N.A.,Gutorov,V.V.,Uvarova,E.A.,Mikheev,M.V.,Sisler,J.R.,Esposito,J.J.,Jahrling,P.B.,Sandakhchiev,L.S.","value":"Senkevich,T.G.,Yutin,N.,Wolf,Y.I.,Koonin,E.V.,Moss,B.,Zmasek,C.M.,Knipe,D.M.,Pellett,P.E.,Scheuermann,R.H.,Shchelkunov,S.N.,Totmenin,A.V.,Babkin,I.V.,Safronov,P.F.,Ryazankina,O.I.,Petrov,N.A.,Gutorov,V.V.,Uvarova,E.A.,Mikheev,M.V.,Sisler,J.R.,Esposito,J.J.,Jahrling,P.B.,Sandakhchiev,L.S."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/NC_003310/1996-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"NC_003310"},"institution":{"value":"Department of Molecular Biology of Genomes, SRC VB Vector, Russia"},"host":{"value":"Homo sapiens"},"date":{"value":"1996-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["T2688A","G9441A","A24393T","C24945T","C26416T","A27114-","T27328C","C29029T","T29031C","T29753C","T29758C","T30743A","T30815A","T30855A","G32024A","A32322G","T32329C","T33159C","G34800A","T34944A","G35230A","G35775A","T37957A","C38427T","T38658A","A39070T","-39072A","T39447C","A40487T","A50294G","G59966C","T60903A","C60947T","T61241C","A61926C","T62169A","G62941T","T65141C","T65870C","A67348G","C67353T","A70503T","T71422C","A73777T","T74112C","A75351T","C76284T","T78525C","A81969-","C82417T","T82548C","T82641G","C83956T","G88318A","T108302C","A115794G","T122451C","T122935C","T122986C","T124980C","T125566C","T125834C","T126192C","T126231C","T126963C","T130725C","A130822C","G134912A","T136637C","T138948C","T139755C","T140893C","T141277A","A141901G","G142068A","A143024T","G143126A","A143187T","A143703G","C143806T","T143895C","C158963T","G161650A","T165054-","C165055-","G166518A","C167064T","T168214-","A168962-","A169025-","T169165-","A169581-","T169894C","A170077G","C182952T","T182953C","C183492A","C183522A","C184979T","A185373G","G185472A","T186503C","T186531G","C186532T","A187305G","A194522T"],"OPG002":["I22L"],"OPG002_dup":["I22L"],"OPG042":["G228R"],"OPG043":["N210D"],"OPG045":["R78G"],"OPG047":["N114Y","E127V","H151L","E481G"],"OPG049":["T275A","M277T"],"OPG054":["A256V"],"OPG056":["N126I","C203Y","T360S"],"OPG057":["N250S"],"OPG059":["Y49*"],"OPG080":["S260G","G358R","P685A"],"OPG082":["T171K"],"OPG085":["L395P"],"OPG089":["K213I"],"OPG091":["F18S"],"OPG097":["D198N"],"OPG101":["F14L"],"OPG105":["K282-","A431V","C475R","Y506D","S944F"],"OPG109":["A377V"],"OPG127":["K175R"],"OPG143":["T289A"],"OPG145":["L345P"],"OPG146":["D25G"],"OPG147":["S52G"],"OPG151":["M601T","E633D"],"OPG153":["N344S"],"OPG156":["I154M"],"OPG160":["K61R"],"OPG161":["L59Q"],"OPG162":["R84G"],"OPG164":["N83Y","E117K","Q137L"],"OPG165":["D63G","I127T"],"OPG185":["A16V"],"OPG188":["G19R"],"OPG191":["A120T"],"OPG192":["H112Y"],"OPG198":["K14E"],"OPG210":["L533S","P713T","P723T","T1340A","A1373T","S1726V"]},"labels":{"aa":"OPG002: I22L; OPG002_dup: I22L; OPG042: G228R; OPG043: N210D; OPG045: R78G; OPG047: N114Y, E127V, H151L, E481G; OPG049: T275A, M277T; OPG054: A256V; OPG056: N126I, C203Y, T360S; OPG057: N250S; OPG059: Y49*; OPG080: S260G, G358R, P685A; OPG082: T171K; OPG085: L395P; OPG089: K213I; OPG091: F18S; OPG097: D198N; OPG101: F14L; OPG105: K282-, A431V, C475R, Y506D, S944F; OPG109: A377V; OPG127: K175R; OPG143: T289A; OPG145: L345P; OPG146: D25G; OPG147: S52G; OPG151: M601T, E633D; OPG153: N344S; OPG156: I154M; OPG160: K61R; OPG161: L59Q; OPG162: R84G; OPG164: N83Y, E117K, Q137L; OPG165: D63G, I127T; OPG185: A16V; OPG188: G19R; OPG191: A120T; OPG192: H112Y; OPG198: K14E; OPG210: L533S, P713T, P723T, T1340A, A1373T, S1726V"}}},{"name":"JX878418","node_attrs":{"div":295,"accession":"JX878418","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878418/2007-01-02"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 07-0120"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-01-02"}},"branch_attrs":{"mutations":{"nuc":["G1934A","A50236G","G60803T","G74360A","G95577A","G116628T","C120371T","C151006A","C174070T","G187369A","A187951C","C195276T"],"OPG002":["T273M"],"OPG002_dup":["T273M"],"OPG069":["Q84R"],"OPG080":["L406I"],"OPG094":["R194H"],"OPG116":["D73N"],"OPG134":["*293Y"],"OPG135":["S95Y"],"OPG137":["A257V"]},"labels":{"aa":"OPG002: T273M; OPG002_dup: T273M; OPG069: Q84R; OPG080: L406I; OPG094: R194H; OPG116: D73N; OPG134: *293Y; OPG135: S95Y; OPG137: A257V"}}}]},{"name":"NODE_0000009","node_attrs":{"div":284,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G32003A"]}},"children":[{"name":"JX878426","node_attrs":{"div":293,"accession":"JX878426","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878426/2007-05-27"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 07-0450"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-05-27"}},"branch_attrs":{"mutations":{"nuc":["G19563A","G38096T","G54227A","-71178A","A72767T","G111583A","T121790C","A160337-","C166976T","C185501T","G189591A"],"OPG005":["M131I"],"OPG034":["A148V"],"OPG071":["T71I"],"OPG092":["S61T"],"OPG130":["T107I"],"OPG141":["I45M"]},"labels":{"aa":"OPG005: M131I; OPG034: A148V; OPG071: T71I; OPG092: S61T; OPG130: T107I; OPG141: I45M"}}},{"name":"JX878408","node_attrs":{"div":284,"accession":"JX878408","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878408/2006-10-31"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 06-0970"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-10-31"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000010","node_attrs":{"div":289,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C7495-","A7496-","A7497-","T7498-","T7499-","A7500-","G24032A","G94972A","G137606T","C149206G","G160867A","C170296A"],"OPG115":["V105I"],"OPG153":["A21E"],"OPG174":["E64Q"],"OPG198":["L87M"]},"labels":{"aa":"OPG115: V105I; OPG153: A21E; OPG174: E64Q; OPG198: L87M"}},"children":[{"name":"JX878420","node_attrs":{"div":289,"accession":"JX878420","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878420/2007-02-26"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 07-0283"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-02-26"}},"branch_attrs":{"mutations":{"nuc":["A8054-"]}}},{"name":"JX878419","node_attrs":{"div":289,"accession":"JX878419","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878419/2007-02-10"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 07-0275"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-02-10"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000011","node_attrs":{"div":259,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T458-","A459-","G460-","C7756A","-140134A","-140135A","-140136C","-140137A","-140138A","-140139T","-140140T","-140141A","-140142T","-146863A","-146864T","-146884T","-146885T","-146886T","-146887A","-146888T","-146889A","-146890T","-146891T","-146892T","-146893T","-146894A","-146895T","G150568-","-169769A","-169771A","-169772G","-169773A","-169774T","-179227A","C196750-","T196751-","A196752-"],"OPG159":["-124N","-125Y","-126N"]},"labels":{"aa":"OPG159: -124N, -125Y, -126N"}},"children":[{"name":"NODE_0000012","node_attrs":{"div":268,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C204A","C790T","C115912T","G148121A","A148344T","G152154A","C155631A","G169205T","C176693T","C177720T","G186892T","G196420A"],"OPG153":["D376V","P390L"],"OPG173":["V29I"],"OPG205":["R689C"],"OPG210":["R1846I"]},"labels":{"aa":"OPG153: D376V, P390L; OPG173: V29I; OPG205: R689C; OPG210: R1846I"}},"children":[{"name":"KP849471","node_attrs":{"div":279,"accession":"KP849471","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Yoshinori,N.,Muyembe,J.-J.,Kingbeni,P.M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Yoshinori,N.,Muyembe,J.-J.,Kingbeni,P.M."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/KP849471/1985-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"Yambuku_DRC_1985"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"date":{"value":"1985-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["G3975A","G12958A","A17046T","G60368A","C83195T","G85079A","G86364A","G133454A","T148337-","G150484A","-150568G","G150582T","G156302A","G180598A","C193235T","G197006T"],"OPG029":["D8E"],"OPG080":["P551S"],"OPG176":["D226N"]},"labels":{"aa":"OPG029: D8E; OPG080: P551S; OPG176: D226N"}}},{"name":"NODE_0000013","node_attrs":{"div":274,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T8510C","C16123A","C51889T","T87138C","G136499A","T136541A","A146877T","T146880A","G151145A","T178510-"],"OPG027":["E85D"]},"labels":{"aa":"OPG027: E85D"}},"children":[{"name":"JX878410","node_attrs":{"div":275,"accession":"JX878410","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878410/2006-11-24"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 06-1070"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-11-24"}},"branch_attrs":{"mutations":{"nuc":["T8470C","-8471T","-148336T"]}}},{"name":"NODE_0000014","node_attrs":{"div":286,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T7058G","G24032A","C69800T","T71738C","C79473A","G104054T","G141897A","G153208A","C162040T","C163571T","G165428A","A170972-","-178510T","A181253-","T183992C","A186633G","A189692-"],"OPG088":["A22T"],"OPG102":["P130H"],"OPG180":["A173T"],"OPG188":["L149F"],"OPG189":["A80V"],"OPG190":["G103S"],"OPG210":["T1760A"]},"labels":{"aa":"OPG088: A22T; OPG102: P130H; OPG180: A173T; OPG188: L149F; OPG189: A80V; OPG190: G103S; OPG210: T1760A"}},"children":[{"name":"JX878412","node_attrs":{"div":289,"accession":"JX878412","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878412/2006-11-30"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 06-1076"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-11-30"}},"branch_attrs":{"mutations":{"nuc":["G15850T","C99681T","C129086T"],"OPG151":["P55S"]},"labels":{"aa":"OPG151: P55S"}}},{"name":"NODE_0000015","node_attrs":{"div":287,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T6937-","G115548A"],"OPG133":["P50L"]},"labels":{"aa":"OPG133: P50L"}},"children":[{"name":"JX878411","node_attrs":{"div":287,"accession":"JX878411","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878411/2006-11-30"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 06-1075"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-11-30"}},"branch_attrs":{"mutations":{}}},{"name":"JX878409","node_attrs":{"div":287,"accession":"JX878409","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878409/2006-11-09"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 06-0999"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-11-09"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000016","node_attrs":{"div":285,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G1750A","G11111A","G14622A","C25557T","C47009T","T49703C","C85076T","A136541T","G140367T","-148336T","C173464T","C188051T","G190541A","C195460T"],"OPG023":["A597V"],"OPG025":["R216C"],"OPG153":["V376D"]},"labels":{"aa":"OPG023: A597V; OPG025: R216C; OPG153: V376D"}},"children":[{"name":"JX878422","node_attrs":{"div":287,"accession":"JX878422","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878422/2007-03-20"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 07-0287"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-03-20"}},"branch_attrs":{"mutations":{"nuc":["A66164C","C144356T"],"OPG084":["Q481H"]},"labels":{"aa":"OPG084: Q481H"}}},{"name":"NODE_0000017","node_attrs":{"div":286,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C187388G"]}},"children":[{"name":"JX878428","node_attrs":{"div":286,"accession":"JX878428","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878428/2007-06-30"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 07-0514"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-06-30"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000018","node_attrs":{"div":288,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T8470C","-8471T","A14622G","T136541A"],"OPG025":["C216R"],"OPG153":["D376V"]},"labels":{"aa":"OPG025: C216R; OPG153: D376V"}},"children":[{"name":"JX878427","node_attrs":{"div":288,"accession":"JX878427","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878427/2007-05-25"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 07-0480"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-05-25"}},"branch_attrs":{"mutations":{"nuc":["C144356-"]}}},{"name":"JX878421","node_attrs":{"div":289,"accession":"JX878421","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878421/2007-03-22"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 07-0286"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-03-22"}},"branch_attrs":{"mutations":{"nuc":["G174812T"],"OPG204":["R94M"]},"labels":{"aa":"OPG204: R94M"}}},{"name":"JX878416","node_attrs":{"div":289,"accession":"JX878416","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878416/2006-12-26"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 07-0093"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-12-26"}},"branch_attrs":{"mutations":{"nuc":["G50130A"],"OPG069":["D49N"]},"labels":{"aa":"OPG069: D49N"}}},{"name":"JX878414","node_attrs":{"div":288,"accession":"JX878414","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878414/2006-12-14"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 07-0046"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-12-14"}},"branch_attrs":{"mutations":{}}},{"name":"JX878415","node_attrs":{"div":288,"accession":"JX878415","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878415/2006-12-26"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 07-0092"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-12-26"}},"branch_attrs":{"mutations":{}}},{"name":"JX878413","node_attrs":{"div":288,"accession":"JX878413","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878413/2006-12-14"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 07-0045"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-12-14"}},"branch_attrs":{"mutations":{}}}]}]}]}]}]},{"name":"NODE_0000020","node_attrs":{"div":263,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G1319T","-46648T","G70874A","C130660T","G135598A","G144341-","-148336T","T159792C","C195891A"],"OPG001":["T86N"],"OPG001_dup":["T86N"],"OPG089":["E337K"]},"labels":{"aa":"OPG001: T86N; OPG001_dup: T86N; OPG089: E337K"}},"children":[{"name":"NODE_0000021","node_attrs":{"div":268,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["-8993A","C8994-","A56010G","C81524T","C94783T","C141329T","G148121A","G150582-","A150583-","T150584-","G150585-","A150586-"],"OPG115":["H42Y"],"OPG173":["V29I"]},"labels":{"aa":"OPG115: H42Y; OPG173: V29I"}},"children":[{"name":"NODE_0000022","node_attrs":{"div":271,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G6645T","G108249A","A133978-","A133979-","C133980-","T148343A","-173286A","-173287T","A184202C"],"OPG127":["H193Y"]},"labels":{"aa":"OPG127: H193Y"}},"children":[{"name":"KC257460","node_attrs":{"div":278,"accession":"KC257460","author":{"author":"Nakazawa,Y.,Emerson,G.L.,Carroll,D.S.,Zhao,H.,Li,Y.,Reynolds,M.G.,Karem,K.L.,Olson,V.A.,Lash,R.R.,Davidson,W.B.,Smith,S.K.,Levine,R.S.,Regnery,R.L.,Sammons,S.A.,Frace,M.A.,Mutasim,E.M.,Karsani,M.E.,Muntasir,M.O.,Babiker,A.A.,Opoka,L.,Chowdhary,V.,Damon,I.K.,Karsani,M.E.M.","value":"Nakazawa,Y.,Emerson,G.L.,Carroll,D.S.,Zhao,H.,Li,Y.,Reynolds,M.G.,Karem,K.L.,Olson,V.A.,Lash,R.R.,Davidson,W.B.,Smith,S.K.,Levine,R.S.,Regnery,R.L.,Sammons,S.A.,Frace,M.A.,Mutasim,E.M.,Karsani,M.E.,Muntasir,M.O.,Babiker,A.A.,Opoka,L.,Chowdhary,V.,Damon,I.K.,Karsani,M.E.M."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/KC257460/1985-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"KC257460"},"institution":{"value":"Biochemistry & Microbiology, University of Victoria, Canada"},"host":{"value":"Homo sapiens"},"date":{"value":"1985-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["A461-","T462-","T463-","G464-","G465-","C466-","A581G","G582-","A583-","T12940-","A12941-","A21066G","G45419T","G46543A","C55215T","C136555-","A136556-","T136557-","C136558-","A136559-","T136560-","G164590A","C169530A","-170918G","G182700T","G183510-","T183511-","C183512-","C183513-","A183514-","A183515-","A183516-","A183517-","T183518-","C183519-","C183520-","G183521-","C183522-","C183523-","A183524-","C183525-","A183526-","A183527-","C183528-","T183529-","T183530-","C183531-","C183532-","C183533-","C183534-","C183535-","T183536-","A183537-","G183538-","A183539-","C183540-","C183541-","A183542-","T196627C","C196630-","T196631-","C196745-","C196746-","A196747-","A196748-","T196749-","G196753-"],"OPG153":["-370D","-371D","D372I","D373I"],"OPG189":["A420T"],"OPG197":["V36T"],"OPG210":["G449C","Q720-","N721-","P722-","P723-","Q724-","L725-","P726-","P727-","R728-","P729-","V730-"]},"labels":{"aa":"OPG153: -370D, -371D, D372I, D373I; OPG189: A420T; OPG197: V36T; OPG210: G449C, Q720-, N721-, P722-, P723-, Q724-, L725-, P726-, P727-, R728-, P729-, V730-"}}},{"name":"NODE_0000023","node_attrs":{"div":282,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C204A","G6146A","T11318C","C19628T","C33967G","T35962C","A42121C","T46648-","C126969T","C138190A","G166163A","G171413A","-173288A","-173289T","-173290A","-173291T","-173292A","-173293T","-173294A","-173295T","-173296A","-173297T","-173298A","-173299T","-173300A","-173301T","C178333T","C179226T","A179227C","A179236G","C191064T","G197006T"],"OPG015":["A4V"],"OPG015_dup":["A4V"],"OPG023":["Y528C"],"OPG052":["S10T"],"OPG054":["Q12R"],"OPG155":["R101I"],"OPG191":["M1I"],"OPG199":["M142I"]},"labels":{"aa":"OPG015: A4V; OPG015_dup: A4V; OPG023: Y528C; OPG052: S10T; OPG054: Q12R; OPG155: R101I; OPG191: M1I; OPG199: M142I"}},"children":[{"name":"HM172544","node_attrs":{"div":324,"accession":"HM172544","author":{"author":"Farlow,J.,Ichou,M.A.,Huggins,J.,Ibrahim,S.,Ait Ichou,M.,Ibrahims,S.","value":"Farlow,J.,Ichou,M.A.,Huggins,J.,Ibrahim,S.,Ait Ichou,M.,Ibrahims,S."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/HM172544/1979-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"Zaire 1979-005"},"institution":{"value":"Virology, The United States Army Medical Research Institute for Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"1979-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["G6897A","C13503T","C24978-","T30041-","C31367T","T33413-","G33447A","C38066A","C42664T","A45990T","T48341A","T50745C","G51355A","T51682C","G52016A","C52389T","C52602T","G53498A","T56271C","A71178-","G75423A","C80549T","G81722A","A82190C","T83083G","G87216A","C87303T","T97494C","C100884T","C102551A","C105412T","G105605A","G116846A","C126632T","G126942A","A135122G","G147239A","C148546T","T149979C","G152106-","C162397T","C164144T","A166358T","T169140A","C175384T","T176564C","T183716C","T189840C"],"OPG025":["A589T"],"OPG051":["T68M"],"OPG063":["R342H"],"OPG070":["V256I"],"OPG071":["A314V","A613T","A684T","T808M"],"OPG095":["M207I"],"OPG105":["K355N","L653R"],"OPG109":["M715I"],"OPG120":["A289T"],"OPG122":["L42I"],"OPG124":["H122Y","S186N"],"OPG148":["S216L"],"OPG174":["A284T"],"OPG178":["G200-"],"OPG188":["H268Y"],"OPG189":["A271V"],"OPG191":["Q66H"]},"labels":{"aa":"OPG025: A589T; OPG051: T68M; OPG063: R342H; OPG070: V256I; OPG071: A314V, A613T, A684T, T808M; OPG095: M207I; OPG105: K355N, L653R; OPG109: M715I; OPG120: A289T; OPG122: L42I; OPG124: H122Y, S186N; OPG148: S216L; OPG174: A284T; OPG178: G200-; OPG188: H268Y; OPG189: A271V; OPG191: Q66H"}}},{"name":"DQ011155","node_attrs":{"div":282,"accession":"DQ011155","author":{"author":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S.","value":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/DQ011155/1978-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"Zaire_1979-005"},"institution":{"value":"Centers for Disease Control and Prevention, National Center for Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"1978-XX-XX"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000024","node_attrs":{"div":285,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T7092-","T7093-","A7094-","C7095-","A7096-","G7097-","T7098-","A7099-","T7100-","A7101-","T7102-","A7103-","C7104-","G7105-","T7106-","T7107-","A7108-","T7109-","T7110-","C8249T","C38214T","C52909T","C63123T","C82622T","C85325T","C85869T","C101013T","G109883A","G117995A","A118781G","C123585T","A125829G","G133473T","G146819-","T146866G","C165490T","C165639A","A184066G","G197132-","A197133-","A197149-","G197150-","A197151-","G197152-","T197153-","T197154-","T197155-","C197156-","C197157-","T197158-","A197159-","C197160-","G197161-","G197162-"],"OPG056":["S274N"],"OPG120":["V246M"],"OPG190":["A173D"],"OPG210":["K904R"]},"labels":{"aa":"OPG056: S274N; OPG120: V246M; OPG190: A173D; OPG210: K904R"}},"children":[{"name":"MT724770","node_attrs":{"div":287,"accession":"MT724770","author":{"author":"Marien,J.,Laudisoit,A.,Patrono,L.V.,Calvignac-Spencer,S.,Leendertz,F.,Leirs,H.,Verheyen,E.","value":"Marien,J.,Laudisoit,A.,Patrono,L.V.,Calvignac-Spencer,S.,Leendertz,F.,Leirs,H.,Verheyen,E."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/MT724770/2014-01-01"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"MT724770"},"institution":{"value":"Biology, Universiteit Antwerpen, Belgium"},"host":{"value":"Crocidura littoralis"},"date":{"value":"2014-01-01"}},"branch_attrs":{"mutations":{"nuc":["C204A","C133072T","-150582G","-150583A","-150584T","-150585G","-150586A","C159210T","G189214A"],"OPG005":["A6T"]},"labels":{"aa":"OPG005: A6T"}}},{"name":"NODE_0000025","node_attrs":{"div":286,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T7090-","T7091-","G7111-","T7112-","C7113-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T180483A"],"OPG159":["N124-","Y125-","N126-"]},"labels":{"aa":"OPG159: N124-, Y125-, N126-"}},"children":[{"name":"MN702449","node_attrs":{"div":286,"accession":"MN702449","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"strain_display":{"value":"Central African Republic/MN702449/2016-01-02"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"MN702449"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"host":{"value":"Homo sapiens"},"date":{"value":"2016-01-02"}},"branch_attrs":{"mutations":{"nuc":["G146866T","T197117A","C197118G","T197121G","A197122T","T197123A","C197127A","A197129T","T197136A","T197138C","A197142T","C197144T","T197166A","G197167T"]}}},{"name":"MN702446","node_attrs":{"div":289,"accession":"MN702446","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"strain_display":{"value":"Central African Republic/MN702446/2018-04-14"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"MN702446"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-04-14"}},"branch_attrs":{"mutations":{"nuc":["A8054-","G10673T","T37120-","G42785A","C179154T","A179162C","-179163C","-179164T","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A181253-","C181732G"],"OPG022":["D62E"],"OPG063":["P302S"],"OPG210":["T126S"]},"labels":{"aa":"OPG022: D62E; OPG063: P302S; OPG210: T126S"}}},{"name":"NODE_0000026","node_attrs":{"div":291,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["A8054-","G18952A","G87276A","C127584T","T148336-","T148337-","A148344T","A151042G","-197132G","-197133A","-197149A","-197150G","-197151A","-197152G","-197153T","-197154T","-197155T","-197156C","-197157C","-197158T","-197159A","-197160C","-197161G","-197162G"],"OPG149":["A130V"]},"labels":{"aa":"OPG149: A130V"}},"children":[{"name":"MN702445","node_attrs":{"div":291,"accession":"MN702445","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"strain_display":{"value":"Central African Republic/MN702445/2017-02-06"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"MN702445"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-02-06"}},"branch_attrs":{"mutations":{"nuc":["C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","G197006T"]}}},{"name":"MN702444","node_attrs":{"div":291,"accession":"MN702444","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"strain_display":{"value":"Central African Republic/MN702444/2017-02-06"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"MN702444"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-02-06"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000027","node_attrs":{"div":264,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G12632A","A146877T","T146880A"],"OPG023":["A90V"]},"labels":{"aa":"OPG023: A90V"}},"children":[{"name":"KJ642613","node_attrs":{"div":276,"accession":"KJ642613","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/KJ642613/1970-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"KJ642613"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"date":{"value":"1970-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["A581G","G582-","A583-","G7469A","C8249T","C13298T","C31628T","-41935T","C50527-","C50528-","T50529-","G50530-","C50531-","A50532-","T50533-","C50534-","T50535-","T50536-","A50537-","T50538-","T50539-","A50540-","G58413A","G63150A","C64611T","G66698T","C79369T","C111519T","G133968A","C136555T","G144316T","G150582T","A150634-","A150635-","T178641-","T196627C","C196630-","T196631-"],"OPG083":["V36I"]},"labels":{"aa":"OPG083: V36I"}}},{"name":"NODE_0000028","node_attrs":{"div":282,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G907A","G3308T","G11575A","T15747-","G31211A","G35067A","G37230T","T57906C","G60984A","G62421A","C87507T","C100648G","T101111C","G136039T","C137054T","A148344T","C154681T","G180556T","G181036A","G189591A","C193902A","C196303T"],"OPG005":["M131I"],"OPG047":["D478N"],"OPG056":["T602N"],"OPG119":["T88R"],"OPG120":["H213R"],"OPG153":["R205H"]},"labels":{"aa":"OPG005: M131I; OPG047: D478N; OPG056: T602N; OPG119: T88R; OPG120: H213R; OPG153: R205H"}},"children":[{"name":"DQ011154","node_attrs":{"div":284,"accession":"DQ011154","author":{"author":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S.","value":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S."},"country":{"value":"Republic of the Congo"},"strain_display":{"value":"Republic of the Congo/DQ011154/2003-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"Congo_2003_358"},"institution":{"value":"National Center for Infectious Diseases, Centers for Disease Control and Prevention (US CDC), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2003-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["C204A","T136541A","G140147A","T140154C","C150750T","C188925A","G197006T"],"OPG153":["D376V"],"OPG159":["C127Y"]},"labels":{"aa":"OPG153: D376V; OPG159: C127Y"}}},{"name":"NODE_0000029","node_attrs":{"div":285,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["A5646G","T6219-","G24996A","C149078T","A189040-","A190994-","T191564C"],"OPG015":["C171R"],"OPG015_dup":["C171R"]},"labels":{"aa":"OPG015: C171R; OPG015_dup: C171R"}},"children":[{"name":"MN702451","node_attrs":{"div":292,"accession":"MN702451","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"strain_display":{"value":"Central African Republic/MN702451/2017-04-14"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"MN702451"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-04-14"}},"branch_attrs":{"mutations":{"nuc":["G39626A","A65771T","G93521T","T136535A","T146865A","A146868T","-150568G","G151440A","T155635-","T155636-","A155637-","G155638-","A155639-","T155640-","A155641-","G155642-","C165304T","C167244T","G171695A","C179163T","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","A179236G","T197117A","C197118G","T197121G","A197122T","T197123A","C197127A","A197129T","G197132-","A197133-","T197134-","T197135-","T197136-","T197137-","T197138-","C197139-","C197143T","C197147-","T197148-","A197149-","G197150-","A197151-","G197152-","T197153-","T197154-","T197155-","C197156-","C197157-","T197158-","A197159-","C197160-","G197161-","G197162-","T197163-","C197164-","G197165-","T197166-","G197167-","G197168-","G197169-","T197170-","C197171-","A197172-","C197173-","A197174-","C197175-","A197176-","T197177-","T197178-","T197179-","T197182C"],"OPG153":["D378V"],"OPG192":["H172Y"]},"labels":{"aa":"OPG153: D378V; OPG192: H172Y"}}},{"name":"KP849469","node_attrs":{"div":287,"accession":"KP849469","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Yoshinori,N.,Muyembe,J.-J.,Kingbeni,P.M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Yoshinori,N.,Muyembe,J.-J.,Kingbeni,P.M."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/KP849469/2008-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"Boende_DRC_2008"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"date":{"value":"2008-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["A10459T","T10460-","A10461-","G135460T","T136538A","G197006T"],"OPG153":["D377V"]},"labels":{"aa":"OPG153: D377V"}}}]},{"name":"NODE_0000030","node_attrs":{"div":285,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["A134C","C33905T","G40666C","T143617C","T146877A","A146880T","G150582-","A150583-","T150584-","G150585-","A150586-","T189889-","T189890-","A189891-","T189892-","T189893-","A189894-","C189895-","G189896-","T189897-","G189898-","A189899-","A189900-","G189901-","A189902-","T189903-","G189904-","A189905-","T189906-","A189907-","T189908-","C189909-","A189910-","T189911-","T189912-","A189913-","A189914-","A189915-","C189916-","C189917-","A189918-","A189919-","C189920-","A189921-","T189922-","T189923-","G189924-","A189925-","G189926-","A189927-","T189928-","T189929-","G189930-","G189931-","C189932-","T189933-","C189934-","T189935-","T189936-","A189937-","T189938-","G189939-","T189940-","T189941-","A189942-","G189943-","C189944-","T189945-","G189946-","G189947-","A189948-","T189949-","T189950-","G189951-","A189952-","A189953-","T189954-","T189955-","A189956-","C189957-","T189958-","G189959-","T189960-","A189961-","A189962-","T189963-","A189964-","A189965-","A189966-","T189967-","G189968-","C189969-","A189970-","T189971-","C189972-","G189973-","A189974-","G189975-","T189976-","A189977-","T189978-","A189979-","G189980-","A189981-","G189982-","G189983-","G189984-","A189985-","T189986-","A189987-","T189988-","A189989-","G189990-","C189991-","A189992-","A189993-","T189994-","T189995-","C189996-","T189997-","C189998-","G189999-","A190000-","T190001-","A190002-","A190003-","T190004-","A190005-","G190006-","T190007-","C190008-","A190009-","T190010-","G190011-","C190012-","A190013-","A190014-","T190015-","A190016-","T190017-","T190018-","T190019-","G190020-","A190021-","A190022-","T190023-","G190024-","A190025-","G190026-","A190027-","C190028-","T190029-","G190030-","A190031-","T190032-","A190033-","A190034-","T190035-","T190036-","T190037-","A190038-","G190039-","G190040-","T190041-","A190042-","A190043-","T190044-","A190045-","C190046-","A190047-","G190048-","T190049-","A190050-","C190051-","T190052-","A190053-","C190054-","A190055-","C190056-","A190057-","C190058-","A190059-","T190060-","A190061-","T190062-","C190063-","T190064-","T190065-","T190066-","C190067-","T190068-","A190069-","G190070-","A190071-","T190072-","T190073-","A190074-","T190075-","A190076-","T190077-","A190078-","T190079-","C190080-","G190081-","T190082-","T190083-","A190084-","A190085-","A190086-","A190087-","A190088-","T190089-","C190090-","T190091-","G190092-","T190093-","A190094-","A190095-","G190096-","A190097-","G190098-","G190099-","T190100-","A190101-","T190102-","A190103-","T190104-","T190105-","T190106-","C190107-","T190108-","C190109-","A190110-","T190111-","A190112-","A190113-","G190114-","T190115-","A190116-","T190117-","C190118-","C190119-","A190120-","C190121-","T190122-","G190123-","T190124-","G190125-","T190126-","A190127-","A190128-","T190129-","A190130-","T190131-","T190132-","A190133-","T190134-","T190135-","A190136-","A190137-","T190138-","G190139-","G190140-","A190141-","T190142-","A190143-","T190144-","A190145-","T190146-","A190147-","G190148-","A190149-","T190150-","A190151-","A190152-","C190153-","A190154-","C190155-","A190156-","A190157-","T190158-","A190159-","G190160-","G190161-","G190162-","A190163-","C190164-","T190165-","A190166-","A190167-","T190168-","A190169-","G190170-","T190171-","A190172-","T190173-","T190174-","G190175-","T190176-","A190177-","A190178-","A190179-","A190180-","G190181-","A190182-","T190183-","A190184-","T190185-","A190186-","A190187-","T190188-","C190189-","G190190-","A190191-","C190192-","T190193-","A190194-","T190195-","T190196-","T190197-","G190200-","T190201-","A190202-","C190203-","A190204-","T190205-","A190206-","T190207-","C190208-","C190209-","A190210-","G190211-","A190212-","T190213-","A190214-","T190215-","C190216-","T190217-","A190218-","T190219-","A190220-","T190221-","T190222-","C190223-","C190224-","T190225-","A190226-","C190227-","T190228-","A190229-","G190230-","T190231-","T190232-","T190233-","G190234-","C190235-","T190236-","G190237-","C190238-","G190239-","T190240-","A190241-","G190242-","T190243-","T190244-","G190245-","C190246-","A190247-","T190248-","C190249-","A190250-","T190251-","T190252-","G190253-","A190254-","T190255-","A190256-","T190257-","G190258-","C190259-","A190260-","T190261-","G190262-","A190263-","T190264-","T190265-","T190266-","A190267-","T190268-","C190269-","A190270-","G190271-","G190272-","A190273-","T190274-","T190275-","C190276-","A190277-","G190278-","A190279-","G190280-","A190281-","T190282-","G190283-","A190284-","A190285-","T190286-","T190287-","A190288-","C190289-","T190290-","A190291-","A190292-","G190293-","T190294-","A190295-","A190296-","A190297-","C190298-","T190299-","A190300-","C190301-","A190302-","A190303-","T190304-","C190305-","C190306-","C190307-","A190308-","C190309-","A190310-","A190311-","T190312-","A190313-","A190314-","G190315-","T190316-","A190317-","A190318-","G190319-","A190320-","A190321-","T190322-","C190323-","A190324-","A190325-","A190326-","T190327-","A190328-","T190329-","C190330-","A190331-","A190332-","A190333-","A190334-","A190335-","C190336-","T190337-","C190338-","A190339-","C190340-","T190341-","T190342-","T190343-","T190344-","G190345-","A190346-","T190347-","T190348-","T190349-","T190350-","T190351-","C190352-","T190353-","A190354-","G190355-","T190356-","C190357-","T190358-","T190359-","A190360-","A190361-","G190362-","T190363-","A190364-","A190365-","T190366-","A190367-","C190368-","A190369-","T190370-","A190371-","T190372-","A190373-","T190374-","T190375-","T190376-","A190377-","T190378-","T190379-","A190380-","A190381-","T190382-","A190383-","G190384-","A190385-","C190386-","C190387-","T190388-","A190389-","T190390-","G190391-","A190392-","A190393-","A190394-","T190395-","A190397-","A190398-","A190399-","A190400-","A190401-","A190402-","G190403-","T190404-","T190405-","A190406-","A190407-","C190408-","A190409-","A190410-","T190411-","G190412-","G190413-","A190414-","T190415-","T190416-","C190417-","G190418-","C190419-","G190420-","T190421-","A190422-","T190423-","A190424-","G190425-","C190426-","T190427-","A190428-","T190429-","T190430-","T190431-","A190432-","C190433-","G190434-","T190435-","A190436-","T190437-","T190438-","A190439-","G190440-","T190441-","A190442-","T190443-","C190444-","G190445-","G190446-","C190447-","A190448-","T190449-","C190450-","T190451-","C190452-","T190453-","T190454-","T190455-","T190456-","G190457-","T190458-","A190459-","T190460-","C190461-","T190462-","T190463-","G190464-","T190465-","T190466-","A190467-","A190468-","T190469-","T190470-","G190471-","T190472-","C190473-","A190474-","C190475-","A190476-","A190477-","A190478-","C190479-","T190480-","A190481-","G190482-","T190483-","A190484-","C190485-","A190486-","T190487-","T190488-","A190489-","C190490-","T190491-","T190492-","C190493-","A190494-","A190495-","T190496-","C190497-","T190498-","G190499-","A190500-","A190501-","A190502-","A190503-","T190504-","A190505-","A190506-","A190507-","T190508-","G190509-","G190510-","T197076G"],"OPG052":["A31T"]},"labels":{"aa":"OPG052: A31T"}},"children":[{"name":"NODE_0000031","node_attrs":{"div":289,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G36971A","G124667A","G125413A","G176109A"],"OPG055":["S38L"],"OPG145":["A241T"],"OPG146":["A76V"],"OPG205":["D152N"]},"labels":{"aa":"OPG055: S38L; OPG145: A241T; OPG146: A76V; OPG205: D152N"}},"children":[{"name":"JX878429","node_attrs":{"div":289,"accession":"JX878429","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878429/2007-09-04"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 07-0662"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-09-04"}},"branch_attrs":{"mutations":{}}},{"name":"JX878425","node_attrs":{"div":289,"accession":"JX878425","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878425/2007-04-20"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 07-0354"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-04-20"}},"branch_attrs":{"mutations":{"nuc":["-144341G"]}}}]},{"name":"NODE_0000032","node_attrs":{"div":288,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T18789C","G58263T","T73298C"],"OPG031":["T14A"]},"labels":{"aa":"OPG031: T14A"}},"children":[{"name":"JX878407","node_attrs":{"div":290,"accession":"JX878407","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878407/2006-10-09"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 06-0950"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-10-09"}},"branch_attrs":{"mutations":{"nuc":["C15207T","C47598T"],"OPG025":["A21T"]},"labels":{"aa":"OPG025: A21T"}}},{"name":"NODE_0000033","node_attrs":{"div":289,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C15349A"]}},"children":[{"name":"JX878424","node_attrs":{"div":289,"accession":"JX878424","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878424/2007-03-25"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 07-0338"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-03-25"}},"branch_attrs":{"mutations":{"nuc":["C179226T","A179227C","A179236G"]}}},{"name":"JX878423","node_attrs":{"div":290,"accession":"JX878423","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/JX878423/2007-03-25"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"DRC 07-0337"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-03-25"}},"branch_attrs":{"mutations":{"nuc":["C108244T"],"OPG127":["M194I"]},"labels":{"aa":"OPG127: M194I"}}}]}]}]},{"name":"NODE_0000034","node_attrs":{"div":283,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["A159953T","C179163T","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","A179218-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","A179236G","T197076G"]}},"children":[{"name":"NODE_0000035","node_attrs":{"div":286,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C4584T","T55501C","T136541A","A168328C","C179217-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"],"OPG074":["Y542C"],"OPG153":["D376V"],"OPG195":["K33N"]},"labels":{"aa":"OPG074: Y542C; OPG153: D376V; OPG195: K33N"}},"children":[{"name":"MN702453","node_attrs":{"div":286,"accession":"MN702453","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"strain_display":{"value":"Central African Republic/MN702453/2001-08-11"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"MN702453"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"host":{"value":"Homo sapiens"},"date":{"value":"2001-08-11"}},"branch_attrs":{"mutations":{}}},{"name":"MN702452","node_attrs":{"div":287,"accession":"MN702452","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"strain_display":{"value":"Central African Republic/MN702452/2010-08-10"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"MN702452"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"host":{"value":"Homo sapiens"},"date":{"value":"2010-08-10"}},"branch_attrs":{"mutations":{"nuc":["C164169T"]}}}]},{"name":"NODE_0000036","node_attrs":{"div":284,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G42564A","-179218G","-179226T"]}},"children":[{"name":"NODE_0000037","node_attrs":{"div":287,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C6624-","G6625-","A6626-","G6627-","T6628-","A6629-","G6630-","T6631-","A6632-","A6633-","C6634-","T6635-","T6636-","C6637-","T6638-","A6639-","A6640-","T6641-","A6642-","A6643-","A6644-","G6645-","A6646-","C6647-","T6648-","T6649-","G6650-","A6651-","T6652-","A6653-","T6654-","C6655-","A6656-","T6657-","T6658-","A6659-","T6660-","C6661-","A6662-","T6663-","A6664-","T6665-","G6666-","T6667-","T6668-","T6669-","G6670-","A6671-","T6672-","C6673-","G6674-","T6675-","C6676-","A6677-","T6678-","A6679-","G6680-","T6681-","T6682-","A6683-","A6684-","T6685-","A6686-","G6687-","T6688-","G6689-","T6690-","G6691-","G6692-","C6693-","T6694-","A6695-","A6696-","A6697-","T6698-","G6699-","G6700-","T6701-","A6702-","C6703-","T6704-","G6705-","T6706-","T6707-","A6708-","A6709-","T6710-","A6711-","A6712-","G6713-","T6714-","T6715-","T6716-","A6717-","T6718-","A6719-","G6720-","A6721-","C6722-","A6723-","A6724-","T6725-","A6726-","T6727-","C6728-","A6729-","T6730-","A6731-","G6732-","T6733-","C6744-","A6745-","G6746-","A6747-","A6748-","T6749-","T6750-","A6751-","G6752-","A6753-","T6754-","T6755-","A6756-","T6757-","T6758-","T6759-","T6760-","T6761-","T6762-","T6763-","A6764-","A6765-","A6766-","T6767-","A6768-","C6769-","T6770-","G6771-","A6772-","T6773-","C6774-","C6775-","T6776-","C6777-","A6778-","C6779-","A6780-","A6781-","T6782-","T6783-","C6784-","C6785-","G6786-","T6787-","G6788-","A6789-","T6790-","G6791-","T6792-","A6793-","G6794-","C6795-","A6796-","G6797-","T6798-","A6799-","G6800-","T6801-","T6802-","G6803-","G6804-","T6805-","G6806-","C6807-","A6808-","T6809-","G6810-","G6811-","T6812-","C6813-","T6814-","A6815-","T6816-","A6817-","T6818-","C6819-","G6820-","T6821-","T6822-","A6823-","A6824-","A6825-","A6826-","T6827-","G6828-","A6835G","T6836G","G6843T","T6846G","C6848-","T6849-","G6850-","A6851-","C6852-","G6853-","T6854-","G6855-","G6856-","A6857-","G6858-","T6859-","A6860-","C6861-","A6862-","G6863-","A6864-","A6865-","T6866-","T6867-","T6868-","T6869-","C6870-","G6871-","A6872-","T6873-","T6874-","A6875-","A6876-","T6877-","G6878-","A6879-","G6880-","T6881-","T6882-","C6883-","A6884-","T6885-","G6886-","G6887-","T6888-","A6889-","A6890-","G6891-","G6892-","A6893-","A6894-","G6895-","G6896-","G6897-","C6898-","A6899-","A6900-","A6901-","T6902-","A117317G","T136535A","G150585-","G150620A","G150621A","A150634-","A150635-","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","G171695A","-173286A","-173287T","-173288A","-173289T","G174029A","-174537G","-174538A","-174539T","-174540G","-174541A","-174542A"],"OPG153":["D378V"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG153: D378V; OPG197: T34-, D35-"}},"children":[{"name":"MN702447","node_attrs":{"div":287,"accession":"MN702447","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"strain_display":{"value":"Central African Republic/MN702447/2018-03-20"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"MN702447"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-03-20"}},"branch_attrs":{"mutations":{}}},{"name":"MN702448","node_attrs":{"div":288,"accession":"MN702448","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"strain_display":{"value":"Central African Republic/MN702448/2018-03-07"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"MN702448"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-03-07"}},"branch_attrs":{"mutations":{"nuc":["G168741A"],"OPG195":["R171K"]},"labels":{"aa":"OPG195: R171K"}}}]},{"name":"NODE_0000038","node_attrs":{"div":288,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G7410A","A146863-","T146864-","T146866-","G169138A","A171639T","G186880A"],"OPG199":["T218S"],"OPG210":["R1842H"]},"labels":{"aa":"OPG199: T218S; OPG210: R1842H"}},"children":[{"name":"MN702450","node_attrs":{"div":297,"accession":"MN702450","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"strain_display":{"value":"Central African Republic/MN702450/2016-01-01"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"MN702450"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"host":{"value":"Homo sapiens"},"date":{"value":"2016-01-01"}},"branch_attrs":{"mutations":{"nuc":["C6388A","G8888A","C47932A","G100885T","G108940A","C122824A","T136532A","T138194A","T146865-","T146867-","A146868-","T146869-","A146870-","T146871-","G172951T","A186911G"],"OPG128":["A39V"],"OPG143":["K164N"],"OPG153":["D379V"],"OPG155":["T100S"],"OPG210":["I1852M"]},"labels":{"aa":"OPG128: A39V; OPG143: K164N; OPG153: D379V; OPG155: T100S; OPG210: I1852M"}}},{"name":"OQ729808","node_attrs":{"div":298,"accession":"OQ729808","author":{"author":"Lee,T.Y.,Hwang,Y.-H.,Yun,M.-R.,Kim,Y.-J.,Kim,D.","value":"Lee,T.Y.,Hwang,Y.-H.,Yun,M.-R.,Kim,Y.-J.,Kim,D."},"country":{"value":"Democratic Republic of the Congo"},"strain_display":{"value":"Democratic Republic of the Congo/OQ729808/2022-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"},"strain":{"value":"MPXV/COD/2023/172V"},"institution":{"value":"Korea National Institute of Health, Division of Infectious Disease Vaccine Research"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["A134C","T29758C","C29763T","G45818A","G70364A","G111683A","C131908A","G133359A","G139736A","-146866G","T146877A","A146880T","T148344A","T179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","G179218A","T179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","G179236A","G188460A"],"OPG089":["D167N"],"OPG130":["P74S"],"OPG158":["R12C"]},"labels":{"aa":"OPG089: D167N; OPG130: P74S; OPG158: R12C"}}}]}]}]}]}]}]}]}]}]},{"name":"NODE_0000039","node_attrs":{"div":305,"clade_membership":{"value":"II"}},"branch_attrs":{"mutations":{"nuc":["C466T","A630C","C720T","G1093A","T1201C","G1504A","G2086T","A2391C","C2554T","G4836T","A5751G","G6076A","G6146A","C7648T","C7810T","G8066A","G8694T","C8923T","G9161T","G9376A","A9509T","A9698G","C10992T","G12003A","A12324C","G12352A","G12380A","G12418T","C13135T","A13223C","A13348G","C13995T","T13999G","T14091C","C14431T","A15602G","C15794T","G16393T","G16406A","A16581G","G16634A","T17496C","C17800T","C18478A","C18953T","C19290T","C19392A","C19457T","G19475A","G20605A","G21034A","G21191A","T22928C","G23080T","G23171A","A23172T","G23173A","A23175G","A23176C","G24032A","C24179T","C25856T","C27614T","C27949T","T28532A","G28548A","T28710C","G31102A","A31144G","C32867T","A33102T","C33656A","C33708A","C34301A","G35613A","C36049T","T37170C","-39072T","C39248T","G40558T","C40565T","T40937C","T41967C","A42516T","G42769A","C43751T","T44972A","G45500A","G45584A","A45637C","G46217A","C46417T","C46427A","T47140G","C47181T","T47735G","G49223T","T49994C","A50595C","G52354T","C52684T","C52938T","A52989C","G53156A","A53257G","C55188T","G55203A","C56531T","G58035T","C58131T","C58965T","G59046A","T59488C","G59709A","G60874C","C61056A","C62823T","C63156T","C63303T","A63976G","G64465A","A65352T","G65663A","G66263A","C66761A","C67245T","C67550T","T69675G","G72261A","G73076A","G75790A","C76123T","G76198A","G76648A","G76911A","C78461A","G78641A","G78942A","T79267C","A79502C","G79829A","T81989C","C83360T","C83843T","G84395A","T85763C","T86502G","T87584C","G88773A","G90493A","C90891T","G91347A","G91489T","C93356T","C95469T","T96651C","A97572G","A99234G","C100341T","A102971C","G103051A","G103424T","C106857A","G107511T","G108793A","G110828T","C111539T","G111545A","T111591A","A113747G","G114458A","C116583T","T116643A","A117014G","G117725T","C118520T","A120174C","C120363T","G121082A","A121453C","G121711A","C122049T","A122422G","C124687T","A125047G","G125334A","G125556A","G126923T","C126969T","C127859T","G128546T","G130030A","C131806T","C132118T","C133280T","G133328A","G133455A","T134233A","G134491A","C134765T","G136190T","C136486A","G136596A","G137026T","C137377T","C137731T","G137925A","C138513T","A138654G","C138746T","G139285T","C139539T","G139771A","C139874T","G143108A","C143392T","T143997C","C144049T","C145074T","G145088T","C145336T","G145523T","C145551A","T146098G","G146215A","G146434A","T146446C","G147904T","T150132C","A150153G","C150488T","C150513T","G150545A","G150780A","G151320A","A151341C","G151923A","A152967T","G153645A","T154702C","T154975C","A155479C","G155843A","G158787T","G159351A","C159530T","T159741C","G159780A","T160924A","T161519A","T162639C","G162720A","A165006G","T165691C","C166934T","C168185T","C168588-","T168769C","A168987C","G169081A","C169142T","G169353A","A169721T","C170037T","G170335A","G172304A","G173102A","G173472A","T173569C","G173974A","A174301G","T175964C","T176453C","A176701G","A176715G","C177517T","C177724T","C178237T","C178311A","A178639G","A178791G","A179023G","T179478C","C179538A","T179589G","C179690T","C180197T","A181364T","C182033T","C182348A","G183491A","C183718T","C183920T","C184286T","A185268G","G185762A","C185900T","C186077T","G186466T","G186505A","A187080-","C187345T","G187498A","C187839T","A187914G","C187964T","C188537T","A188726G","C188747A","G188812A","A189179T","C189909A","A190154G","-190396A","T190404G","G190596T","T190648A","G191051A","C191064T","A191401G","T191459C","C192374A","T192471C","T194819G","C195124A","C195706T","A196009G","C196117T","G196490A","G196744A"],"OPG002":["S121A"],"OPG002_dup":["S121A"],"OPG015":["A4V","F136L"],"OPG015_dup":["A4V","F136L"],"OPG016":["A63S","V80E"],"OPG021":["I38V"],"OPG023":["A174V","S193A","H300Y","E637K"],"OPG024":["G32S"],"OPG025":["K393E","V425I"],"OPG029":["R146C"],"OPG030":["D12N","N113S"],"OPG031":["E117D"],"OPG034":["R205L"],"OPG036":["P11S"],"OPG037":["R415C"],"OPG038":["P27H","I78V"],"OPG043":["A3T"],"OPG044":["L148M"],"OPG045":["T185A"],"OPG049":["V17E"],"OPG056":["Y622C"],"OPG059":["L26I"],"OPG063":["A307V"],"OPG064":["S88A"],"OPG065":["D23N"],"OPG066":["R83K","N97H"],"OPG068":["E341D"],"OPG071":["T428I","S484A","V501I"],"OPG074":["D199N"],"OPG079":["Y45C"],"OPG080":["E321D","S382C"],"OPG084":["T211S"],"OPG085":["A328T","V591F"],"OPG096":["M68I"],"OPG100":["Q152K"],"OPG101":["A153T"],"OPG102":["V249I"],"OPG109":["T622A"],"OPG111":["V77I"],"OPG112":["R34H"],"OPG130":["A122T"],"OPG135":["E90V"],"OPG145":["R463Q"],"OPG148":["S313I"],"OPG150":["E256D"],"OPG153":["H358Y","P493Q"],"OPG154":["R107H"],"OPG156":["S42Y","A222T"],"OPG157":["V24M"],"OPG159":["A2T","S36L"],"OPG164":["V111I"],"OPG165":["L161S"],"OPG167":["S107Y","V112I"],"OPG170":["I111M"],"OPG172":["D160Y"],"OPG176":["S227L"],"OPG178":["V139I"],"OPG185":["T205I"],"OPG187":["*300K"],"OPG195":["S120-"],"OPG197":["T18S"],"OPG198":["V100I"],"OPG200":["G52D"],"OPG205":["Y349C","S354G","A621V","A690V"],"OPG208":["T142I","A311V"],"OPG210":["L3F","N331K","A788V","T1305A","R1704L","G1717D"]},"labels":{"aa":"OPG002: S121A; OPG002_dup: S121A; OPG015: A4V, F136L; OPG015_dup: A4V, F136L; OPG016: A63S, V80E; OPG021: I38V; OPG023: A174V, S193A, H300Y, E637K; OPG024: G32S; OPG025: K393E, V425I; OPG029: R146C; OPG030: D12N, N113S; OPG031: E117D; OPG034: R205L; OPG036: P11S; OPG037: R415C; OPG038: P27H, I78V; OPG043: A3T; OPG044: L148M; OPG045: T185A; OPG049: V17E; OPG056: Y622C; OPG059: L26I; OPG063: A307V; OPG064: S88A; OPG065: D23N; OPG066: R83K, N97H; OPG068: E341D; OPG071: T428I, S484A, V501I; OPG074: D199N; OPG079: Y45C; OPG080: E321D, S382C; OPG084: T211S; OPG085: A328T, V591F; OPG096: M68I; OPG100: Q152K; OPG101: A153T; OPG102: V249I; OPG109: T622A; OPG111: V77I; OPG112: R34H; OPG130: A122T; OPG135: E90V; OPG145: R463Q; OPG148: S313I; OPG150: E256D; OPG153: H358Y, P493Q; OPG154: R107H; OPG156: S42Y, A222T; OPG157: V24M; OPG159: A2T, S36L; OPG164: V111I; OPG165: L161S; OPG167: S107Y, V112I; OPG170: I111M; OPG172: D160Y; OPG176: S227L; OPG178: V139I; OPG185: T205I; OPG187: *300K; OPG195: S120-; OPG197: T18S; OPG198: V100I; OPG200: G52D; OPG205: Y349C, S354G, A621V, A690V; OPG208: T142I, A311V; OPG210: L3F, N331K, A788V, T1305A, R1704L, G1717D","clade":"clade II"}},"children":[{"name":"NODE_0000040","node_attrs":{"div":393,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["G580T","C4693-","T4694-","T4695-","C6433T","C6439T","A6448T","C6453A","A6475T","A6481G","C6483A","C6486G","A6494G","A6496G","C6505G","G6519T","T6521A","G6524T","T6525A","A6529C","A6538G","C6547A","C6552T","G6557T","G6577A","T6580A","A6597T","A6601C","G6613A","A6620G","G6625C","T6635A","T6641G","A6644G","C6647T","T6648A","G6650A","T6654A","C6661G","G6666T","T6667C","C6673A","G6674T","T6675C","T6681C","G6687T","G6689A","T6698A","G6699A","A6702G","C6703T","T6704A","T6707G","A6709G","T6714A","T6715G","C6722G","A6724G","T6725C","C6728G","A6747C","T6750A","T6754G","T6758G","A6764G","T6767G","G6771C","A6772T","C6777G","G6786A","T6792A","G6794A","G6797T","A6799T","G6800A","T6801A","G6804A","G6810T","T6814G","C6819T","A6823G","T6831G","A6835C","A6839G","T6841G","T6845A","G6853A","G6871C","T6882A","A6889G","G6892A","G6895-","G6896-","G6897-","C6898-","G6903A","A6913T","A6916T","T6917A","A6920-","G6924C","T6925A","T6926A","A6927C","A6928C","A6930T","T6932G","T6936C","T6945G","A6953T","C6955T","A6958T","A6959T","A6964C","A6965T","G6976T","T6979A","T6989C","C6994A","C6995G","T7001A","A7004G","C7018A","C7020A","C7022A","T7025C","C7026G","T7029A","C7037G","T7043G","C7046T","C7050A","T7058A","C7062G","G7063T","T7065G","C7068-","T7075C","G7078A","A7579-","C7864T","T8015C","A8055-","A8143G","T8499-","G8841A","T8993-","T9054C","A11365G","C11745T","G12947A","C18109T","T19324A","A21111-","G22308A","C23190T","C23747T","G23966A","G24232-","C24233-","A24234-","C24977T","C25368-","C29203A","C30510T","G30699T","C31454A","G32326A","A33199-","T33414-","C35859T","C36732T","A42426G","A54013G","G55750A","G58482T","A70398C","G76393A","G77451A","C79658T","G80435T","G84373A","C85145T","A86916G","G87055A","C89607T","G89869A","G90034A","A91246-","A91247-","T91248-","G91249-","G91250-","A91251-","G91737A","G93422A","G94404T","G97371A","C99287T","G99587A","G100967A","A104985G","G106460T","G107366T","G125514T","T130846C","A131548G","T132813-","T133086-","T133087-","T133088-","T133089-","T133090-","T133091-","T133092-","T133093-","T133094-","T133095-","T133096-","T133097-","T133098-","T133177-","C133178-","T133179-","T133180-","T133181-","C133182-","T133183-","C133184-","A133185-","A133186-","C133539T","G133682A","G136446A","T136641C","A137515G","G140772A","G142337A","A146877-","T146878-","T146879-","T146880-","T146881-","A146882-","T146883-","A147926T","A148124G","C148542T","A150569-","T150570-","A150571-","T150572-","G150573-","A150574-","T150575-","G150576-","G150577-","A150578-","T150579-","A150580-","T150581-","G150582-","A150583-","T150584-","G150585-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G150603-","A150604-","T150605-","A150606-","T150607-","G150608-","A150609-","T150610-","G150611-","C153210A","G153894A","C156081T","C156162A","C156414-","A156415-","G156448A","A156548-","G156549-","C157280T","A157678-","A157679-","A157680-","A157681-","T157682-","T157683-","T157684-","T157685-","A157686-","A157687-","G157688-","C157689-","G157690-","A157691-","T157692-","G157693-","A157694-","T157695-","A157696-","A158027-","T158028-","A158029-","C158981T","G159964T","C160120T","G161760A","T166103-","T166104-","A166105-","A166106-","T166107-","A166108-","A166109-","T166110-","T166111-","A166112-","A166113-","T166114-","A166115-","A166116-","T168446-","A168447-","A169574G","A169763-","C169764-","A169765-","A169767-","-169772A","G169814-","A169815-","A169816-","G170283A","G170918-","G171068A","A172092-","T172524C","T172667-","T173283-","A173284-","T173285-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","G173318-","A173501-","T173502-","G173544A","G173641A","T173745-","G175396A","A177073G","C178285T","T179072-","G179076-","C179423T","G181076A","A181114-","T181115-","T181116-","C181117-","C181118-","T181119-","T181120-","A181121-","T181122-","C182411A","C182600T","C183466A","-187080T","G187398-","T187399-","A187400-","C187401-","C189273T","T189744-","A192515-","A192516-","G192517-","C196630A","A197082G"],"OPG023":["D386N"],"OPG040":["E37D","A168T"],"OPG045":["E20D"],"OPG047":["L166I","D229N"],"OPG049":["P276S"],"OPG055":["A118T"],"OPG074":["S459F"],"OPG089":["E178A"],"OPG102":["H192Y"],"OPG105":["S1083N"],"OPG108":["A2V"],"OPG110":["V80I","A135T"],"OPG113":["A3T"],"OPG118":["A281V","G381D"],"OPG120":["A261V"],"OPG123":["V29A"],"OPG125":["H97N","L399I"],"OPG153":["T343A","H408Y"],"OPG163":["V46I"],"OPG172":["D167V"],"OPG173":["T30A"],"OPG174":["C285Y"],"OPG185":["T22I"],"OPG195":["Y73-","D74-","Q75-","C76-","T77-","E78-","P79-","H80-","D81-","F82-","I83-","I84-","T85-","D86-","T87-","Q88-","Q89-","T90-","R91-","L92-","G93-","S94-","S95-","H96-","T97-","Y98-","I99-","K100-","F101-","S102-","N103-","M104-","N105-","T106-","G107-","V108-","P109-","S110-","S111-","I112-","P113-","K114-","C115-","S116-","R117-","T118-","L119-","I121-","S122-","V123-","Y124-","C125-","D126-","Q127-","E128-","A129-","G130-","D131-","I132-","K133-","F134-","E135-","E136-","Y137-","T138-","Q139-","E140-","S141-","S142-","D143-","I144-","S145-","I146-","R147-","V148-","K149-","Y150-","D151-","S152-","S153-","C154-","I155-","D156-","Y157-","L158-","G159-","I160-","N161-","Q162-","S163-","F164-","M165-","N166-","E167-","C168-","I169-","R170-","R171-","I172-","T173-","T174-","W175-","D176-","R177-","E178-","S179-","C180-","V181-","R182-","I183-","D184-","T185-","Q186-","T187-","I188-","N189-","K190-","Y191-","L192-","K193-","S194-","C195-","T196-","N197-","T198-","K199-","F200-","D201-","R202-","N203-","V204-","Y205-","K206-","R207-","Y208-"],"OPG197":["D33-","D35N","E49-"],"OPG204":["E289K"],"OPG205":["H473R"],"OPG208":["T53I"],"OPG209":["G187R"],"OPG210":["S704Y"]},"labels":{"aa":"OPG023: D386N; OPG040: E37D, A168T; OPG045: E20D; OPG047: L166I, D229N; OPG049: P276S; OPG055: A118T; OPG074: S459F; OPG089: E178A; OPG102: H192Y; OPG105: S1083N; OPG108: A2V; OPG110: V80I, A135T; OPG113: A3T; OPG118: A281V, G381D; OPG120: A261V; OPG123: V29A; OPG125: H97N, L399I; OPG153: T343A, H408Y; OPG163: V46I; OPG172: D167V; OPG173: T30A; OPG174: C285Y; OPG185: T22I; OPG195: Y73-, D74-, Q75-, C76-, T77-, E78-, P79-, H80-, D81-, F82-, I83-, I84-, T85-, D86-, T87-, Q88-, Q89-, T90-, R91-, L92-, G93-, S94-, S95-, H96-, T97-, Y98-, I99-, K100-, F101-, S102-, N103-, M104-, N105-, T106-, G107-, V108-, P109-, S110-, S111-, I112-, P113-, K114-, C115-, S116-, R117-, T118-, L119-, I121-, S122-, V123-, Y124-, C125-, D126-, Q127-, E128-, A129-, G130-, D131-, I132-, K133-, F134-, E135-, E136-, Y137-, T138-, Q139-, E140-, S141-, S142-, D143-, I144-, S145-, I146-, R147-, V148-, K149-, Y150-, D151-, S152-, S153-, C154-, I155-, D156-, Y157-, L158-, G159-, I160-, N161-, Q162-, S163-, F164-, M165-, N166-, E167-, C168-, I169-, R170-, R171-, I172-, T173-, T174-, W175-, D176-, R177-, E178-, S179-, C180-, V181-, R182-, I183-, D184-, T185-, Q186-, T187-, I188-, N189-, K190-, Y191-, L192-, K193-, S194-, C195-, T196-, N197-, T198-, K199-, F200-, D201-, R202-, N203-, V204-, Y205-, K206-, R207-, Y208-; OPG197: D33-, D35N, E49-; OPG204: E289K; OPG205: H473R; OPG208: T53I; OPG209: G187R; OPG210: S704Y","clade":"clade IIa"}},"children":[{"name":"NODE_0000041","node_attrs":{"div":464,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["C334T","T602-","T603-","T604-","T605-","T606-","C3299A","T4722-","G4723-","A4724-","T4754-","G4755-","A4756-","G7610A","T8335-","T10992C","C11237A","G12496T","G13465C","T16524C","G20501T","G22164A","C22169T","A23203G","A23289T","-25368A","A32972C","T33806C","T37110C","G40684T","T45966A","A45971-","T45972-","T45980-","T47499A","C50255T","G55330T","G64427A","C66773T","G71925A","C77775A","A78461C","A80583C","G83661A","A84278G","G88566T","C92630A","G103421A","C107921T","T108250C","C113843T","T125262C","G132531A","A133442G","C134489T","C135792T","C136794T","G138298A","C141072T","G141294A","G144604A","T147634G","G150612-","A150613-","T150614-","A150615-","T150616-","G150617-","A150618-","T150619-","G150620-","G155105A","C155392T","T156215C","T156724-","G159963A","C160171T","G161470A","T162663G","A162722G","G163020T","C163836T","G165637T","T168345A","A168371-","C168372-","T168373-","G168374-","A168375-","T168376-","T168377-","G168378-","C168379-","A168380-","G168381-","T168382-","G168383-","T168384-","T168385-","C168386-","A168387-","T168388-","C168389-","G168390-","C168391-","C168392-","C168393-","A168394-","A168395-","C168396-","T168397-","G168398-","C168399-","A168400-","A168401-","G168402-","T168403-","G168404-","G168405-","A168406-","G168407-","G168408-","A168409-","T168410-","T168411-","G168412-","A168413-","T168414-","A168415-","A168416-","C168417-","T168418-","G168419-","A168420-","A168421-","G168422-","G168423-","C168424-","A168425-","A168426-","T168427-","G168428-","G168429-","A168430-","T168431-","T168432-","C168433-","A168434-","G168435-","A168436-","G168437-","T168438-","A168439-","G168440-","T168441-","T168442-","A168443-","T168444-","A168445-","T168448-","G168449-","A168450-","T168451-","C168452-","A168453-","A168454-","T168455-","G168456-","T168457-","A168458-","C168459-","A168460-","G168461-","A168462-","A168463-","C168464-","C168465-","C168466-","C168467-","A168468-","T168469-","G168470-","A168471-","C168472-","T168473-","T168474-","T168475-","A168476-","T168477-","T168478-","A168479-","T168480-","C168481-","A168482-","C168483-","C168484-","G168485-","A168486-","T168487-","A168488-","C168489-","T168490-","C168491-","A168492-","A168493-","C168494-","A168495-","A168496-","A168497-","C168498-","A168499-","C168500-","G168501-","T168502-","C168503-","T168504-","T168505-","G168506-","G168507-","A168508-","T168509-","C168510-","A168511-","T168512-","C168513-","T168514-","C168515-","A168516-","T168517-","A168518-","C168519-","A168520-","T168521-","A168522-","T168523-","A168524-","T168525-","T168526-","A168527-","A168528-","A168529-","T168530-","T168531-","C168532-","A168533-","G168534-","T168535-","A168536-","A168537-","C168538-","A168539-","T168540-","G168541-","A168542-","A168543-","T168544-","A168545-","C168546-","A168547-","G168548-","G168549-","T168550-","G168551-","T168552-","C168553-","C168554-","C168555-","A168556-","T168557-","C168558-","T168559-","A168560-","G168561-","T168562-","A168563-","T168564-","T168565-","C168566-","C168567-","A168568-","A168569-","A168570-","A168571-","T168572-","G168573-","T168574-","T168575-","C168576-","C168577-","A168578-","G168579-","A168580-","A168581-","C168582-","T168583-","C168584-","T168585-","C168586-","T168587-","T168589-","A168590-","T168591-","T168592-","T168593-","C168594-","T168595-","G168596-","T168597-","A168598-","T168599-","A168600-","T168601-","T168602-","G168603-","T168604-","G168605-","A168606-","T168607-","C168608-","A168609-","A168610-","G168611-","A168612-","G168613-","G168614-","C168615-","G168616-","G168617-","G168618-","A168619-","G168620-","A168621-","C168622-","A168623-","T168624-","A168625-","A168626-","A168627-","A168628-","T168629-","T168630-","T168631-","G168632-","A168633-","G168634-","G168635-","A168636-","G168637-","T168638-","A168639-","T168640-","A168641-","C168642-","T168643-","C168644-","A168645-","A168646-","G168647-","A168648-","A168649-","T168650-","C168651-","A168652-","A168653-","G168654-","T168655-","G168656-","A168657-","T168658-","A168659-","T168660-","C168661-","A168662-","G168663-","T168664-","A168665-","T168666-","T168667-","A168668-","G168669-","A168670-","G168671-","T168672-","T168673-","A168674-","A168675-","G168676-","T168677-","A168678-","T168679-","G168680-","A168681-","T168682-","T168683-","C168684-","A168685-","T168686-","C168687-","A168688-","T168689-","G168690-","T168691-","A168692-","T168693-","T168694-","G168695-","A168696-","T168697-","T168698-","A168699-","T168700-","C168701-","T168702-","G168703-","G168704-","G168705-","T168706-","A168707-","T168708-","T168709-","A168710-","A168711-","T168712-","C168713-","A168714-","A168715-","A168716-","G168717-","T168718-","T168719-","T168720-","C168721-","A168722-","T168723-","G168724-","A168725-","A168726-","T168727-","G168728-","A168729-","A168730-","T168731-","G168732-","T168733-","A168734-","T168735-","T168736-","C168737-","G168738-","A168739-","A168740-","G168741-","A168742-","A168743-","T168744-","T168745-","A168746-","C168747-","A168748-","A168749-","C168750-","A168751-","T168752-","G168753-","G168754-","G168755-","A168756-","T168757-","A168758-","G168759-","A168760-","G168761-","A168762-","A168763-","T168764-","C168765-","A168766-","T168767-","G168768-","C168769-","G168770-","T168771-","C168772-","A168773-","G168774-","A168775-","A168776-","T168777-","T168778-","G168779-","A168780-","T168781-","A168782-","C168783-","A168784-","C168785-","A168786-","G168787-","A168788-","C168789-","T168790-","A168791-","T168792-","A168793-","A168794-","A168795-","T168796-","A168797-","A168798-","A168799-","T168800-","A168801-","T168802-","C168803-","T168804-","T168805-","A168806-","A168807-","G168808-","T168809-","C168810-","T168811-","T168812-","G168813-","C168814-","A168815-","C168816-","C168817-","A168818-","A168819-","C168820-","A168821-","C168822-","A168823-","A168824-","A168825-","A168826-","T168827-","T168828-","C168829-","G168830-","A168831-","C168832-","C168833-","G168834-","T168835-","A168836-","A168837-","T168838-","G168839-","T168840-","C168841-","T168842-","A168843-","C168844-","A168845-","A168846-","A168847-","A168848-","G168849-","G168850-","T168851-","A168852-","C168945T","-169767T","T170754C","G172736A","C173569T","C174990T","C175537T","C178666T","-179072A","-179076T","C180258T","A180482-","T180483-","T180484-","A180485-","A180486-","A180487-","A180488-","A180489-","C181298T","T183552A","C187489T","G187888A","C188575T","C189627A","C192455-","A192456-","T192457-","C192487-","A192488-","T192489-","G193911T","A196610-","A196611-","A196612-","A196613-","A196614-","G196876A"],"OPG003":["D437Y"],"OPG003_dup":["D437Y"],"OPG019":["A11T"],"OPG023":["N135K","R555L","K637E"],"OPG025":["N601K"],"OPG037":["V89M"],"OPG039":["V277D"],"OPG052":["K64E"],"OPG074":["T599N"],"OPG083":["T97M"],"OPG085":["V587M"],"OPG099":["F37L"],"OPG100":["K152Q"],"OPG105":["V846I"],"OPG109":["D294E"],"OPG145":["M439T"],"OPG153":["A292T"],"OPG155":["T65I"],"OPG160":["M1I"],"OPG161":["A65T"],"OPG172":["S70A"],"OPG181":["A232T"],"OPG188":["N356K","Q376R"],"OPG195":["I39N","T48-","D49-","C50-","S51-","V52-","H53-","R54-","P55-","T56-","A57-","S58-","G59-","G60-","L61-","I62-","T63-","E64-","G65-","N66-","G67-","F68-","R69-","V70-","V71-","I72-"],"OPG197":["T32V"],"OPG204":["H336Y"],"OPG210":["L733I"]},"labels":{"aa":"OPG003: D437Y; OPG003_dup: D437Y; OPG019: A11T; OPG023: N135K, R555L, K637E; OPG025: N601K; OPG037: V89M; OPG039: V277D; OPG052: K64E; OPG074: T599N; OPG083: T97M; OPG085: V587M; OPG099: F37L; OPG100: K152Q; OPG105: V846I; OPG109: D294E; OPG145: M439T; OPG153: A292T; OPG155: T65I; OPG160: M1I; OPG161: A65T; OPG172: S70A; OPG181: A232T; OPG188: N356K, Q376R; OPG195: I39N, T48-, D49-, C50-, S51-, V52-, H53-, R54-, P55-, T56-, A57-, S58-, G59-, G60-, L61-, I62-, T63-, E64-, G65-, N66-, G67-, F68-, R69-, V70-, V71-, I72-; OPG197: T32V; OPG204: H336Y; OPG210: L733I"}},"children":[{"name":"MT903346","node_attrs":{"div":464,"accession":"MT903346","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"USA"},"strain_display":{"value":"USA/MT903346/2003-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"North America"},"strain":{"value":"MPXV-USA2003_099_Gambian_Rat"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"host":{"value":"Cricetomys gambianus"},"date":{"value":"2003-XX-XX"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000042","node_attrs":{"div":465,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["-602T","C137626T","-196610A"]}},"children":[{"name":"MT903347","node_attrs":{"div":465,"accession":"MT903347","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"USA"},"strain_display":{"value":"USA/MT903347/2003-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"North America"},"strain":{"value":"MPXV-USA2003_099_Dormouse"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"host":{"value":"Gliridae"},"date":{"value":"2003-XX-XX"}},"branch_attrs":{"mutations":{}}},{"name":"DQ011153","node_attrs":{"div":465,"accession":"DQ011153","author":{"author":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S.","value":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S."},"country":{"value":"USA"},"strain_display":{"value":"USA/DQ011153/2003-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"North America"},"strain":{"value":"DQ011153"},"institution":{"value":"National Center for Infectious Diseases, Centers for Disease Control and Prevention (US CDC), USA"},"host":{"value":"Cynomys"},"date":{"value":"2003-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["C49T"]}}},{"name":"MT903348","node_attrs":{"div":465,"accession":"MT903348","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"USA"},"strain_display":{"value":"USA/MT903348/2003-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"North America"},"strain":{"value":"MPXV-USA2003_099_Rope_Squirrel"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"host":{"value":"Funisciurus"},"date":{"value":"2003-XX-XX"}},"branch_attrs":{"mutations":{}}},{"name":"DQ011157","node_attrs":{"div":465,"accession":"DQ011157","author":{"author":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S.","value":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S."},"country":{"value":"USA"},"strain_display":{"value":"USA/DQ011157/2003-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"North America"},"strain":{"value":"DQ011157"},"institution":{"value":"National Center for Infectious Diseases, Centers for Disease Control and Prevention (US CDC), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2003-XX-XX"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000045","node_attrs":{"div":406,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["G707A","C2959T","G3843A","C5441A","-7068A","A7069G","G7186A","C13709T","T19165A","T28278C","T38382A","G47813T","G85661A","A85968G","A88560T","T97911C","C115877T","C136555-","A136556-","T136557-","C136558-","A136559-","T136560-","A136561-","T136562-","C136563-","T136570-","A161541-","-168588C","T170904-","G174537-","A174538-","T174539-","G174540-","A174541-","A174542-","T180475-","T180476-","A180477-","A180478-","A180479-","A180480-","A180481-","G191769T","C193367T","G194251A","C196503T"],"OPG003":["S550N"],"OPG003_dup":["S550N"],"OPG015":["W239L"],"OPG015_dup":["W239L"],"OPG025":["C520Y"],"OPG056":["D218V"],"OPG107":["K153E"],"OPG134":["A43V"],"OPG153":["E366-","D372-"]},"labels":{"aa":"OPG003: S550N; OPG003_dup: S550N; OPG015: W239L; OPG015_dup: W239L; OPG025: C520Y; OPG056: D218V; OPG107: K153E; OPG134: A43V; OPG153: E366-, D372-"}},"children":[{"name":"NODE_0000046","node_attrs":{"div":433,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["A2760-","A2761-","G3051A","-4693C","-4694T","-4695T","C5809T","T13272-","A13273-","A15512-","C15513-","G15514-","T15515-","C15516-","A15517-","A15518-","T15519-","G15520-","G15521-","T15522-","A15523-","C15524-","A15525-","A15526-","A15527-","T15528-","T15529-","T15530-","T15531-","A15532-","C19281T","G19891A","T20697C","T24732C","-25368A","G36310T","T38583C","T48389G","T62580A","C71655G","C79980T","T80764G","C87501T","C93701T","A95738G","C125798T","-133086T","G133115-","C145219A","A156894C","A164460T","C164835T","-169763A","-169764C","-169765A","-169767A","A169772G","A172087T","-172092A","G178332T","-179072A","-179076T","T180075A","T180218C","A183473G","G191401A","-192515A","-192516A","-192517G","C194159T","T194449-","T194450-"],"OPG034":["R39C"],"OPG036":["D123G"],"OPG044":["V63A"],"OPG056":["N151S"],"OPG091":["L96V"],"OPG102":["T299I"],"OPG104":["N86H"],"OPG147":["V64M"],"OPG197":["-33D","N35D"],"OPG208":["N270K","F318S"]},"labels":{"aa":"OPG034: R39C; OPG036: D123G; OPG044: V63A; OPG056: N151S; OPG091: L96V; OPG102: T299I; OPG104: N86H; OPG147: V64M; OPG197: -33D, N35D; OPG208: N270K, F318S"}},"children":[{"name":"KJ642616","node_attrs":{"div":452,"accession":"KJ642616","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"France"},"strain_display":{"value":"France/KJ642616/1968-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"Europe"},"strain":{"value":"KJ642616"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"date":{"value":"1968-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["T580G","T19608C","T23228A","T24498A","G27605A","C29763T","C37493T","T56538G","A87055G","C102787T","C112599A","G119877A","G121660T","C125897T","G133059A","G133454A","-136561A","-136562T","-136563C","-136570A","T146884-","T146885-","T146886-","A146887-","T146888-","A146889-","T146890-","G150612-","A150613-","T150614-","A150615-","T150616-","G150617-","A150618-","T150619-","G150620-","C156438A","A157609C","C158379T","A160363-","G160364-","G163255A","G168753T","A196630C"],"OPG034":["Y133C"],"OPG040":["Q327H"],"OPG047":["D478N"],"OPG074":["K196N"],"OPG108":["V2A"],"OPG147":["A31T"],"OPG153":["-366D","-372D"]},"labels":{"aa":"OPG034: Y133C; OPG040: Q327H; OPG047: D478N; OPG074: K196N; OPG108: V2A; OPG147: A31T; OPG153: -366D, -372D"}}},{"name":"NODE_0000047","node_attrs":{"div":436,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["-607T","C7611A","C65892T","G116640A","C133521-","A136543-","T136544-","C136545-","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","T136571-","C136572-","G148317-","-196615A"],"OPG019":["A11D"],"OPG084":["P391S"],"OPG135":["S91L"],"OPG153":["D367-","D368-","D369-","D373-","D374-","D375-"]},"labels":{"aa":"OPG019: A11D; OPG084: P391S; OPG135: S91L; OPG153: D367-, D368-, D369-, D373-, D374-, D375-"}},"children":[{"name":"AY753185","node_attrs":{"div":441,"accession":"AY753185","author":{"author":"Chen,N.,Li,G.,Liszewski,M.K.,Atkinson,J.P.,Jahrling,P.B.,Feng,Z.,Schriewer,J.,Buck,C.,Wang,C.,Lefkowitz,E.J.,Esposito,J.J.,Harms,T.,Damon,I.K.,Roper,R.L.,Upton,C.,Buller,R.M.,Buller,R.M.L.","value":"Chen,N.,Li,G.,Liszewski,M.K.,Atkinson,J.P.,Jahrling,P.B.,Feng,Z.,Schriewer,J.,Buck,C.,Wang,C.,Lefkowitz,E.J.,Esposito,J.J.,Harms,T.,Damon,I.K.,Roper,R.L.,Upton,C.,Buller,R.M.,Buller,R.M.L."},"strain_display":{"value":"nan/AY753185/1958-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"},"strain":{"value":"AY753185"},"institution":{"value":"Biochemistry & Microbiology, University of Victoria, Canada"},"date":{"value":"1958-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["A16608G","G32868A","G50614A","C137466T","C170999T","A181253-"],"OPG049":["S95L"],"OPG070":["D9N"],"OPG153":["E68K"]},"labels":{"aa":"OPG049: S95L; OPG070: D9N; OPG153: E68K"}}},{"name":"AY603973","node_attrs":{"div":439,"accession":"AY603973","author":{"author":"Chen,N.,Li,G.,Liszewski,M.K.,Atkinson,J.P.,Jahrling,P.B.,Feng,Z.,Schriewer,J.,Buck,C.,Wang,C.,Lefkowitz,E.J.,Esposito,J.J.,Harms,T.,Damon,I.K.,Roper,R.L.,Upton,C.,Buller,R.M.,Buller,R.M.L.","value":"Chen,N.,Li,G.,Liszewski,M.K.,Atkinson,J.P.,Jahrling,P.B.,Feng,Z.,Schriewer,J.,Buck,C.,Wang,C.,Lefkowitz,E.J.,Esposito,J.J.,Harms,T.,Damon,I.K.,Roper,R.L.,Upton,C.,Buller,R.M.,Buller,R.M.L."},"strain_display":{"value":"nan/AY603973/1961-XX-XX"},"clade_membership":{"value":"IIa"},"strain":{"value":"AY603973"},"institution":{"value":"Biochemistry & Microbiology, University of Victoria, Canada"},"date":{"value":"1961-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["G775A","G90845A","G92261A","A124807G","-146877A","-146878T","-146879T","-146880T","-146881T","-146882A","-146883T","A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","C196435T"],"OPG111":["S194N"]},"labels":{"aa":"OPG111: S194N"}}}]}]},{"name":"NODE_0000048","node_attrs":{"div":417,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["T4087G","A4864G","G7927A","G10999A","T25369-","C25370-","C28393T","C43244T","T69852C","C133520T","G135371A","A150549-","-150585G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-150603G","-150604A","-150605T","-150606A","-150607T","-150608G","-150609A","-150610T","-150611G","T154017C","A163207-","A163208-","C163209-","T163210-","A163211-","A163212-","C163213-","T163214-","-169767T","T179068-","T179069-","A179070-","T179071-","T179073-","A179074-","T179075-","A179077-","T179078-","C190338T","T192346C","A193123C"],"OPG003":["E174A"],"OPG003_dup":["E174A"],"OPG040":["D37-"],"OPG063":["V149I"]},"labels":{"aa":"OPG003: E174A; OPG003_dup: E174A; OPG040: D37-; OPG063: V149I"}},"children":[{"name":"AY741551","node_attrs":{"div":451,"accession":"AY741551","author":{"author":"Chen,N.,Li,G.,Liszewski,M.K.,Atkinson,J.P.,Jahrling,P.B.,Feng,Z.,Schriewer,J.,Buck,C.,Wang,C.,Lefkowitz,E.J.,Esposito,J.J.,Harms,T.,Damon,I.K.,Roper,R.L.,Upton,C.,Buller,R.M.,Buller,R.M.L.","value":"Chen,N.,Li,G.,Liszewski,M.K.,Atkinson,J.P.,Jahrling,P.B.,Feng,Z.,Schriewer,J.,Buck,C.,Wang,C.,Lefkowitz,E.J.,Esposito,J.J.,Harms,T.,Damon,I.K.,Roper,R.L.,Upton,C.,Buller,R.M.,Buller,R.M.L."},"country":{"value":"Sierra Leone"},"strain_display":{"value":"Sierra Leone/AY741551/1970-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"},"strain":{"value":"Sierra Leone"},"institution":{"value":"Biochemistry & Microbiology, University of Victoria, Canada"},"date":{"value":"1970-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G2387A","G3432A","A4696-","A4697-","C4698-","T4699-","A4700-","A4701-","C4702-","T4703-","T4704-","A4705-","T4706-","G4707-","A4708-","C4709-","T4710-","T4711-","A4712-","A4713-","C4714-","T4715-","A4716-","A4717-","C4718-","T4719-","T4720-","A4721-","T4722-","G4723-","A4724-","C4725-","T4726-","T4727-","A4728-","A4729-","C4730-","T4731-","A4732-","A4733-","C4734-","T4735-","T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","A4748-","A4749-","C4750-","T4751-","T4752-","A4753-","T4754-","G4755-","A4756-","C4757-","T4758-","T4759-","A4760-","A4761-","C4762-","T4763-","A4764-","A4765-","C4766-","T4767-","T4768-","A4769-","T4770-","G4771-","A4772-","C4773-","T4774-","T4775-","G5777T","T6916A","A6917T","A6918C","-6920A","A6922-","A6923-","C6924G","A6925T","A6926T","C6927T","C6928A","T6929A","T6930A","G6932T","T6934C","C6936T","C6940T","G6945T","T6952G","T6953A","T6955C","T6957A","T6958A","T6959A","A6961T","C6964A","T6965A","A6968T","C6970G","T6976G","T6977A","A6979T","T6980A","G6982A","C18480T","A21930G","C28278T","G28324A","C29640T","G79597A","C79729A","G84125A","C84980T","C89970T","G94626A","C94743T","G95525A","C110255T","G118298T","C123888A","G133545A","G134297T","C134622T","G134915A","-136570T","A150545-","T150546-","G150547-","A150548-","G150550-","G150551-","A150552-","T150553-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","A152605T","C154167A","C154410T","A160211-","A160212-","C161917T","C163183-","T163184-","C163185-","T163186-","T163187-","T163188-","T163189-","T163190-","A163191-","A163192-","C163193-","T163194-","A163195-","A163196-","C163197-","T163198-","A163199-","A163200-","C163201-","T163202-","A163203-","A163204-","C163205-","T163206-","C163215-","T163216-","T163217-","A163218-","T163219-","G165759A","G172195A","C175461A","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","G180374A","A185597G","C188478T","C188879T","A189894G","C191433A","A192435-","A192436-","G192437-","T192438-","C192439-","A192440-","T192441-","A192442-","A192443-","G192444-","T192445-","T192446-","A192447-","G192448-","T192449-","T192450-","A192451-","A192452-","G192453-","T192454-","C192455-","A192456-","T192457-","A192458-","A192459-","G192460-","T192461-","T192462-","A192463-","G192464-","T192465-","T192466-","A192467-","A192468-","G192469-","T192470-","C192471-","A192472-","T192473-","A192474-","A192475-","G192476-","T192477-","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-","A192490-","A192491-","G192492-","T192493-","T192494-","A192495-","G192496-","T192497-","T192498-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","C193778T","C194823T","-196615A","-196616A","-196617A"],"OPG002":["S122L"],"OPG002_dup":["S122L"],"OPG015":["A127E"],"OPG015_dup":["A127E"],"OPG031":["D117N"],"OPG153":["-366E"],"OPG190":["S213N"],"OPG197":["T32V"],"OPG200":["G16R"]},"labels":{"aa":"OPG002: S122L; OPG002_dup: S122L; OPG015: A127E; OPG015_dup: A127E; OPG031: D117N; OPG153: -366E; OPG190: S213N; OPG197: T32V; OPG200: G16R"}}},{"name":"NODE_0000049","node_attrs":{"div":446,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["T600-","T601-","T602-","T603-","T604-","T605-","T606-","G8774A","A8794G","G9698A","C15082T","C20362T","C33964T","C38427T","C45637T","C50494A","C50572T","C55215A","G72890T","A81454C","G93357A","G121527T","G125116A","C128093T","T132868C","G133163A","G133255A","G133428-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","T136571-","C136572-","A142508G","C150444A","-150549T","-150569A","-150570T","-150571A","-150572T","-150573G","-150574A","-150575T","-150576G","-150577G","-150578A","-150579T","-150580A","-150581T","-150582G","-150583A","-150584T","G151505T","C154806T","T156450A","G156637T","C160271G","A169757-","C169758-","A169759-","G169760-","A169761-","T169762-","C188457T","T189549C","A189726-","T189727-","T189728-","A196608-","A196609-","A196610-","A196611-","A196612-","A196613-","A196614-"],"OPG021":["V38I"],"OPG035":["G15S"],"OPG044":["V63A"],"OPG052":["R11Q"],"OPG056":["C203Y"],"OPG064":["A88T"],"OPG092":["Q20K"],"OPG105":["E110A"],"OPG113":["A543T"],"OPG140":["H74N"],"OPG153":["D367-","D368-","D369-"],"OPG163":["I103V"],"OPG181":["A132V"],"OPG197":["T30V","D31-","T32-"]},"labels":{"aa":"OPG021: V38I; OPG035: G15S; OPG044: V63A; OPG052: R11Q; OPG056: C203Y; OPG064: A88T; OPG092: Q20K; OPG105: E110A; OPG113: A543T; OPG140: H74N; OPG153: D367-, D368-, D369-; OPG163: I103V; OPG181: A132V; OPG197: T30V, D31-, T32-"}},"children":[{"name":"KP849470","node_attrs":{"div":462,"accession":"KP849470","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Yoshinori,N.,Muyembe,J.-J.,Kingbeni,P.M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Yoshinori,N.,Muyembe,J.-J.,Kingbeni,P.M."},"country":{"value":"C\u00f4te d'Ivoire"},"strain_display":{"value":"C\u00f4te d'Ivoire/KP849470/1971-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"},"strain":{"value":"Cote d'Ivoire_1971"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"date":{"value":"1971-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["A9454-","C15863-","C15864-","T15865-","T50665-","C52231T","C65466T","T72702C","C72750T","A86790G","G105195A","A111561G","G116852A","A121165C","T134625G","T136553-","C136554-","G136573-","C141287T","C151475A","C162897T","-163207A","-163208A","-163209C","-163210T","-163211A","-163212A","-163213C","-163214T","T163407C","C167177T","A169751-","C169752-","A169753-","G169754-","A169755-","T169756-","A171862C"],"OPG070":["F26-"],"OPG092":["M66I"],"OPG197":["T28V","D29-","V30-"],"OPG199":["E292A"]},"labels":{"aa":"OPG070: F26-; OPG092: M66I; OPG197: T28V, D29-, V30-; OPG199: E292A"}}},{"name":"NODE_0000050","node_attrs":{"div":448,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["C7A","A14T","G19A","G21A","C23T","T38A","T51A","G54A","C60T","G66A","T68A","A79C","T88A","G8143T","A28532-","G156023A","A197122C","T197131G","A197142T","C197144T","G197150A","C197156T","A197159T","A197172T","T197182A","A197186C","T197192A","T197196A","G197203T"],"OPG044":["M148-"],"OPG153":["-372D"]},"labels":{"aa":"OPG044: M148-; OPG153: -372D"}},"children":[{"name":"DQ011156","node_attrs":{"div":451,"accession":"DQ011156","author":{"author":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S.","value":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S."},"country":{"value":"Liberia"},"strain_display":{"value":"Liberia/DQ011156/1970-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"},"strain":{"value":"DQ011156"},"institution":{"value":"National Center for Infectious Diseases, Centers for Disease Control and Prevention (US CDC), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"1970-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["C39509T","G42709T","A145551G","-179068T","-179069T","-179070A","-179071T","-179072A","-179073T","-179074A","-179075T","-179076T","-179077A","-179078T"],"OPG063":["T327K"]},"labels":{"aa":"OPG063: T327K"}}},{"name":"NODE_0000051","node_attrs":{"div":461,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["-600T","-601T","-602T","A2840C","A6577G","A6580T","T6581A","T6588A","A6590C","C6593T","T6594A","C6601A","G6607C","G10039A","C12561T","A15700-","G15701-","G46380A","A69837G","C89937A","C101011A","A116643G","G140316A","C159500A","T172828A","G187503T","G188419T","A190071-","T190072-","T194370G","-196608A","-196609A","-196610A"],"OPG023":["V114I"],"OPG065":["A35V"],"OPG135":["V90A"],"OPG185":["A195E"]},"labels":{"aa":"OPG023: V114I; OPG065: A35V; OPG135: V90A; OPG185: A195E"}},"children":[{"name":"KJ136820","node_attrs":{"div":465,"accession":"KJ136820","author":{"author":"Radonic,A.,Metzger,S.,Dabrowski,P.W.,Couacy-Hymann,E.,Schuenadel,L.,Kurth,A.,Matz-Rensing,K.,Boesch,C.,Leendertz,F.H.,Nitsche,A.","value":"Radonic,A.,Metzger,S.,Dabrowski,P.W.,Couacy-Hymann,E.,Schuenadel,L.,Kurth,A.,Matz-Rensing,K.,Boesch,C.,Leendertz,F.H.,Nitsche,A."},"country":{"value":"C\u00f4te d'Ivoire"},"strain_display":{"value":"C\u00f4te d'Ivoire/KJ136820/2012-03-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"},"strain":{"value":"KJ136820"},"institution":{"value":"Centre for Biological Security, Robert Koch Institute, Germany"},"host":{"value":"Platyrrhini"},"date":{"value":"2012-03-XX"}},"branch_attrs":{"mutations":{"nuc":["C4538T","T16298C","G35634A","A167909C","-179068T","-179069T","-179070A","-179071T","-179072A","-179073T","-179074A","-179075T","-179076T","-179077A","-179078T","G192672A"],"OPG003":["D24N"],"OPG003_dup":["D24N"],"OPG027":["N27S"]},"labels":{"aa":"OPG003: D24N; OPG003_dup: D24N; OPG027: N27S"}}},{"name":"NODE_0000052","node_attrs":{"div":465,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["T4722-","G4723-","A4724-","C4725-","T4726-","T4727-","A4728-","A4729-","C4730-","T4731-","A4732-","A4733-","G4739A","C4741-","T4742-","T4743-","G21441A","A27251G","-28532A","-136556A","-136557T","-136558C","-136559A","-136560T","-136563C","-136564A","-136565T","-136566C","-136567A","-136568T","-136569C","-136570A","-136571T","-136572C","-146877A","-146878T","-146879T","-146880T","-146881T","-146882A","-146883T","A150545-","T150546-","G150547-","A150548-","T150549-","G150550-","G150551-","A150552-","T150553-","A150569-","T150570-","A150571-","T150572-","G150573-","A150574-","T150575-","G150576-","G150577-","A150578-","T150579-","A150580-","T150581-","G150582-","A150583-","T150584-","G150585-","-169757A","-169758C","-169759A","-169760G","-169761A","-169762T","-169763A","-169764C","-169765A","T169767A","A169772G","T179120-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","C186017T","A192467-","A192468-","G192469-","C192471T","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-"],"OPG044":["-148M"],"OPG153":["-366D","-367D","-368D","-369D"],"OPG197":["V30T","-31D","-32T","-33D","N35D"]},"labels":{"aa":"OPG044: -148M; OPG153: -366D, -367D, -368D, -369D; OPG197: V30T, -31D, -32T, -33D, N35D"}},"children":[{"name":"NODE_0000053","node_attrs":{"div":471,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["-603T","-604T","A4744-","A4745-","C4746-","T4747-","A4748-","A4749-","C4750-","T4751-","T4752-","A4753-","T4754-","G4755-","A4756-","C4757-","T4758-","T4759-","G57148A","C137932T","T145515-","C152375A","G155747T","G158403A","G177534T","T179183-","T179184-","A179185-","T179186-","-196611A","-196612A"],"OPG154":["G40E"],"OPG205":["D627Y"]},"labels":{"aa":"OPG154: G40E; OPG205: D627Y"}},"children":[{"name":"MN346703","node_attrs":{"div":471,"accession":"MN346703","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346703/2018-05-20"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"},"strain":{"value":"MPXV_TNP_2018_East_Placali"},"institution":{"value":"Robert Koch Institute, Project Group Epidemiology of Highly Pathogenic Microorganisms"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2018-05-20"}},"branch_attrs":{"mutations":{"nuc":["-605T","-136561A","-136562T","-179068A","-179069T","-179070A","-179071C","-179074A","-179075T","-179076T","-179077A","-179078T","-179120T","-179122A","-179123T","-179124A","-179125T","-179126A","-196613A"]}}},{"name":"MN346702","node_attrs":{"div":471,"accession":"MN346702","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346702/2018-05-11"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"},"strain":{"value":"MPXV_TNP_2018_East_Paddy"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2018-05-11"}},"branch_attrs":{"mutations":{"nuc":["A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179121-"]}}}]},{"name":"NODE_0000054","node_attrs":{"div":470,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["A22266-","T22267-","G22268-","A22269-","A22270-","G22271-","A22272-","A22273-","G22274-","T22275-","T22276-","C22277-","T22278-","T22279-","C22280-","T22281-","C44980T","C131652T","C133187-","A133188-","T133189-","T133190-","T133191-","C133192-","A133193-","T133194-","C133195-","C133196-","C133197-","C133198-","A133199-","T133200-","G133201-","C133202-","T133204A","T133749C","-136561A","-136562T","C153524A","G156651T","T169721A"],"OPG037":["E52-","E53-","L54-","L55-","H56-"],"OPG064":["D307N"],"OPG151":["T910I"],"OPG180":["T278K"],"OPG197":["S18T"]},"labels":{"aa":"OPG037: E52-, E53-, L54-, L55-, H56-; OPG064: D307N; OPG151: T910I; OPG180: T278K; OPG197: S18T"}},"children":[{"name":"MN346700","node_attrs":{"div":470,"accession":"MN346700","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346700/2017-01-31"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"},"strain":{"value":"MPXV_TNP_2017_South_Ravel_2"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-01-31"}},"branch_attrs":{"mutations":{"nuc":["-22266A","-22267T","-22268G","-22269A","-22270A","-22271G","-22272A","-22273A","-22274G","-22275T","-22276T","-22277C","-22278T","-22279T","-22280C","-22281T","A136561-","T136562-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","T150567-","G150568-","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179121-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-"],"OPG037":["-52E","-53E","-54L","-55L","-56H"]},"labels":{"aa":"OPG037: -52E, -53E, -54L, -55L, -56H"}}},{"name":"MN346699","node_attrs":{"div":470,"accession":"MN346699","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346699/2017-01-23"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"},"strain":{"value":"MPXV_TNP_2017_South_Ravel_1"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-01-23"}},"branch_attrs":{"mutations":{"nuc":["-22266A","-22267T","-22268G","-22269A","-22270A","-22271G","-22272A","-22273A","-22274G","-22275T","-22276T","-22277C","-22278T","-22279T","-22280C","-22281T","A136561-","T136562-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","T150567-","G150568-","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179121-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-"],"OPG037":["-52E","-53E","-54L","-55L","-56H"],"OPG153":["D366-"]},"labels":{"aa":"OPG037: -52E, -53E, -54L, -55L, -56H; OPG153: D366-"}}},{"name":"MN346698","node_attrs":{"div":470,"accession":"MN346698","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346698/2017-01-24"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"},"strain":{"value":"MPXV_TNP_2017_South_Pushkin"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-01-24"}},"branch_attrs":{"mutations":{"nuc":["-22266A","-22267T","-22268G","-22269A","-22270A","-22271G","-22272A","-22273A","-22274G","-22275T","-22276T","-22277C","-22278T","-22279T","-22280C","-22281T","A136561-","T136562-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","T150567-","G150568-","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","A169721T","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179121-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-"],"OPG037":["-52E","-53E","-54L","-55L","-56H"],"OPG197":["T18S"]},"labels":{"aa":"OPG037: -52E, -53E, -54L, -55L, -56H; OPG197: T18S"}}},{"name":"MN346701","node_attrs":{"div":470,"accession":"MN346701","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346701/2017-01-14"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"},"strain":{"value":"MPXV_TNP_2017_South_Woodstock"},"institution":{"value":"Robert Koch Institute, Project Group Epidemiology of Highly Pathogenic Microorganisms"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-01-14"}},"branch_attrs":{"mutations":{"nuc":["-603T","-604T","-605T","G610-","T611-","-22266A","-22267T","-22268G","-22269A","-22270A","-22271G","-22272A","-22273A","-22274G","-22275T","-22276T","-22277C","-22278T","-22279T","-22280C","-22281T","A136556-","T136557-","C136558-","A136559-","T136560-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","T150567-","G150568-","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-196611A"],"OPG037":["-52E","-53E","-54L","-55L","-56H"]},"labels":{"aa":"OPG037: -52E, -53E, -54L, -55L, -56H"}}},{"name":"MN346697","node_attrs":{"div":470,"accession":"MN346697","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346697/2017-04-14"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"},"strain":{"value":"MPXV_TNP_2017_North_Surprise_2"},"institution":{"value":"Robert Koch Institute, Project Group Epidemiology of Highly Pathogenic Microorganisms"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-04-14"}},"branch_attrs":{"mutations":{"nuc":["A15924-","T15925-","T15926-","A15927-","A15928-","T15929-","C15930-","C15931-","A15932-","T15933-","G15934-","G15935-","A15936-","C15937-","T15938-","C15939-","A15940-","T15941-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-"]}}},{"name":"MN346696","node_attrs":{"div":470,"accession":"MN346696","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346696/2017-04-03"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"},"strain":{"value":"MPXV_TNP_2017_North_Surprise_1"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-04-03"}},"branch_attrs":{"mutations":{"nuc":["-179120T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A"]}}},{"name":"MN346695","node_attrs":{"div":470,"accession":"MN346695","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346695/2017-04-02"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"},"strain":{"value":"MPXV_TNP_2017_North_Sidonie"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-04-02"}},"branch_attrs":{"mutations":{"nuc":["A169721T","T179183-"],"OPG197":["T18S"]},"labels":{"aa":"OPG197: T18S"}}},{"name":"MN346692","node_attrs":{"div":470,"accession":"MN346692","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346692/2017-03-05"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"},"strain":{"value":"MPXV_TNP_2017_North_Mama"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-03-05"}},"branch_attrs":{"mutations":{"nuc":["-179120T","-179122A","-179123T","-179124A","-179125T","-179126A","-179127C","-179128A","-179129T","-179130T","-179131A","-179132T","-179133A","-179134T","-179135A","-179136C","-179137A","-179138T","-179139T","-179140A","-179141T","-179142A","-179143T","-179144A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A"]}}},{"name":"MN346694","node_attrs":{"div":470,"accession":"MN346694","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346694/2017-03-28"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"},"strain":{"value":"MPXV_TNP_2017_North_Saro"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-03-28"}},"branch_attrs":{"mutations":{"nuc":["-179120T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A"]}}},{"name":"MN346690","node_attrs":{"div":470,"accession":"MN346690","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346690/2017-03-13"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"},"strain":{"value":"MPXV_TNP_2017_North_Bic"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-03-13"}},"branch_attrs":{"mutations":{"nuc":["-179139T","-179140A","-179141T","-179142A","-179143T","-179144A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A"]}}},{"name":"MN346691","node_attrs":{"div":470,"accession":"MN346691","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346691/2017-03-11"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"},"strain":{"value":"MPXV_TNP_2017_North_Environmental"},"institution":{"value":"Robert Koch Institute, Project Group Epidemiology of Highly Pathogenic Microorganisms"},"date":{"value":"2017-03-11"}},"branch_attrs":{"mutations":{"nuc":["T6822C","G6823C","A6826G","T6829A","G6831T","A6833C","T6834G","C6835A","T6836G","T6838A","G6839A","G6841T","T6844C","A6845T","C6852A","T6854G","G6855A","C6861G","A6865G","T6874C","T6881A","A6882T","T6885C","G6889A","A6892G","A6894G","-6895A","-6896G","-6897G","-6898C","A6899C","A6901T","A6903G","A6911T","T6913A","A6917T","A6918C","-6920A","A6922T","A6923T","C6924-","A6925T","A6926T","C6927A","C6928A","T6930G","G6932T","T6933G","C6936T","G6945T","T6946A","T6947A","T6952C","T6953A","T6955C","T6958G","C6964A","T6965A","T6967G","T6969C","A6971T","T6972A","T6976G","G6978T","A6979C","G6982T","T6983A","G6984T","G6987A","C6989T","G6992A","A6994T","G6995T","A7000C","A7001T","T7003A","G7004A","T7007G","C7014T","A7018C","A7020C","G7021T","A7022C","C7024T","C7025T","G7026C","A7029T","T7033A","G7037C","A7041C","T7046C","A7050C","A7052G","C7053A","A7058T","A7059G","G7062C","T7063G","G7065T","A7068C","G7069A","-179180A","-179181C","-179182A","-196611A"]}}}]}]}]}]}]}]}]}]},{"name":"NODE_0000055","node_attrs":{"div":473,"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C128T","G1687A","C1813A","G1814T","G3099T","G3420A","A4691G","T6429C","A6430T","T6904C","T6977C","T6983-","C7005T","G7950T","T8286C","C8422T","C10267A","G10275A","T10641C","C11439T","G11593A","G11624A","G12712A","G12733A","G16788T","T18017A","A18861T","C19055T","T19304A","T20990A","G22575T","C24222T","G24358T","C24719G","G25173T","T25212G","G25407A","T25769G","A27215G","C28090A","T29446C","C29655T","T30500A","A31039G","A31793G","A32364G","C32477A","C33043T","C33963T","T34005C","G34295A","C34685T","A48148C","C51168T","C55805T","C58467T","C59256T","C67827T","G73821A","C74303G","C74382T","C78728A","A80756G","G81063A","T81182C","G81463T","T82838A","G84333A","C85163T","G86225A","G86535A","G87049A","C87501T","G87735A","C89214T","G89579T","G91023A","A92009G","G92102A","T92237C","A95477C","G95795A","G98430T","G99212A","G99683A","C99830T","C106115T","A107232G","T107394C","G109382A","A109580G","C111716T","A116660G","T120252C","G120965A","C124737T","C124988G","G126255A","C132719A","G133201A","C133733T","C133966T","G134884A","G135706A","G136498A","G136604A","G136687A","G136870A","C143426T","C145803A","A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","C147860T","A148126G","T149765G","C150444T","T150756C","G154405A","C156426T","G156512A","G156954A","C156978T","T157273G","G157437A","C157490T","C158175A","G158398A","G158403A","G158511A","G158668T","G159415A","A159447C","C160152T","C161574T","G161799A","G162291A","C162828T","C163467T","C164848T","C165304T","G166399T","T167126C","C167858T","C168277A","-168588G","G169603A","G170248A","G170435A","A172087T","G172188A","G172980A","G173150A","C173441T","G173809A","C173810T","T173882C","C174170T","A175065C","C176160T","G177167T","C178275T","G178395A","G178540A","A178887G","G181350A","G181994A","G182443A","G182491A","C183008T","G183695A","C183696T","G184137A","T187421C","C188096A","G189418A","G189811T","G190098T","A190772C","T192519C","C193790T","C194111A","C195396A","G195397T","C195523T"],"OPG002":["T313N"],"OPG002_dup":["T313N"],"OPG005":["D74N"],"OPG016":["E121D"],"OPG019":["R124M"],"OPG021":["R230K"],"OPG022":["D73G"],"OPG023":["A426V","A488T"],"OPG031":["K271M"],"OPG036":["E25D"],"OPG040":["A254P","S374Y"],"OPG046":["N95S"],"OPG047":["K232I"],"OPG049":["V37M","M263T"],"OPG054":["G438R"],"OPG074":["V441I"],"OPG094":["T175R"],"OPG105":["G113V","V1070I"],"OPG108":["A4V"],"OPG118":["R256K","S413N","A462V"],"OPG125":["V514I"],"OPG130":["A63T"],"OPG145":["T264I","P348A"],"OPG153":["T355I","-370I","-371I"],"OPG164":["H217Y"],"OPG172":["T145M"],"OPG185":["A167T","E177D"],"OPG189":["R506C"],"OPG191":["C80F"],"OPG195":["-120C"],"OPG198":["D71N","R133Q"],"OPG204":["K178N"],"OPG205":["R169W"],"OPG210":["R363H","G379D","P781S","A928T"]},"labels":{"aa":"OPG002: T313N; OPG002_dup: T313N; OPG005: D74N; OPG016: E121D; OPG019: R124M; OPG021: R230K; OPG022: D73G; OPG023: A426V, A488T; OPG031: K271M; OPG036: E25D; OPG040: A254P, S374Y; OPG046: N95S; OPG047: K232I; OPG049: V37M, M263T; OPG054: G438R; OPG074: V441I; OPG094: T175R; OPG105: G113V, V1070I; OPG108: A4V; OPG118: R256K, S413N, A462V; OPG125: V514I; OPG130: A63T; OPG145: T264I, P348A; OPG153: T355I, -370I, -371I; OPG164: H217Y; OPG172: T145M; OPG185: A167T, E177D; OPG189: R506C; OPG191: C80F; OPG195: -120C; OPG198: D71N, R133Q; OPG204: K178N; OPG205: R169W; OPG210: R363H, G379D, P781S, A928T","clade":"clade IIb"}},"children":[{"name":"KJ642617","node_attrs":{"div":480,"accession":"KJ642617","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/KJ642617/1971-XX-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"KJ642617"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"date":{"value":"1971-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["G13625A","G98489-","C98727T","T119718C","A129762G","G149744A","G160174T","C160852T","A169769-","C169770-","A169771-","A169773-","T169774-","A181253-","-187080A","A187083-"],"OPG025":["T548M"],"OPG151":["D280G"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG025: T548M; OPG151: D280G; OPG197: T34-, D35-"}}},{"name":"NODE_0000056","node_attrs":{"div":501,"lineage":{"value":"A"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","G3450A","C8893A","A16608G","G18312A","C19367T","-32210A","-32211C","-32212G","C33143T","G38067A","G46895A","A48138G","C48527A","C53207A","G66580A","C80986T","T92516C","C100562T","T105126C","G128076A","C133099T","C133145T","C136555T","C136558G","G137627A","-140134A","-140135A","-140136C","-140137A","-140138A","-140139T","-140140T","-140141A","-140142T","G141300A","C141364T","C142450A","T146687C","A149878G","-158170A","G160867A","-166656T","-166657T","G167656T","-169772G","G171675A","-174531G","-174532A","-174533T","-174534G","-174535A","-174536A","G178423A","-187080T","C193760T","-196615A"],"OPG049":["-314R"],"OPG056":["A323V"],"OPG071":["W411L"],"OPG084":["R620Q"],"OPG104":["A12T"],"OPG150":["D100N"],"OPG153":["T14M"],"OPG159":["-124N","-125Y","-126N"],"OPG161":["E67K","A88V"],"OPG170":["D31G"],"OPG176":["N24D"],"OPG191":["-166F"],"OPG193":["R108I"],"OPG199":["E230K"]},"labels":{"aa":"OPG049: -314R; OPG056: A323V; OPG071: W411L; OPG084: R620Q; OPG104: A12T; OPG150: D100N; OPG153: T14M; OPG159: -124N, -125Y, -126N; OPG161: E67K, A88V; OPG170: D31G; OPG176: N24D; OPG191: -166F; OPG193: R108I; OPG199: E230K","clade":"A"}},"children":[{"name":"NC_063383","node_attrs":{"div":506,"accession":"NC_063383","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Senkevich,T.G.,Yutin,N.,Wolf,Y.I.,Koonin,E.V.,Moss,B.,Zmasek,C.M.,Knipe,D.M.,Pellett,P.E.,Scheuermann,R.H.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Senkevich,T.G.,Yutin,N.,Wolf,Y.I.,Koonin,E.V.,Moss,B.,Zmasek,C.M.,Knipe,D.M.,Pellett,P.E.,Scheuermann,R.H."},"lineage":{"value":"A"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/NC_063383/2018-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV-M5312_HM12_Rivers"},"institution":{"value":"National Center for Biotechnology Information, NIH"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","G18769A","C28175T","G81977A","G100261A","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","C154408T","-196616A","-196617A"],"OPG118":["E606K"]},"labels":{"aa":"OPG118: E606K"}}},{"name":"MK783031","node_attrs":{"div":505,"accession":"MK783031","author":{"author":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J.","value":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J."},"lineage":{"value":"A"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/MK783031/2017-11-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MK783031"},"institution":{"value":"NCEZID/DHCPP/PRB, Centers for Disease Control & Prevention (US CDC), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-11-09"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C5157T","G7764A","G9782A","G109736A","C133161T","G192053A"],"OPG015":["D334N"],"OPG015_dup":["D334N"],"OPG019":["R62K"],"OPG021":["A66T"]},"labels":{"aa":"OPG015: D334N; OPG015_dup: D334N; OPG019: R62K; OPG021: A66T"}}},{"name":"OP535319","node_attrs":{"div":523,"accession":"OP535319","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"lineage":{"value":"A"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP535319/2017-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV_Nigeria_2017_5205"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-12-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C8634T","C14067T","C33332T","C67253T","C110326T","C117099T","C122737T","G125303A","G129583A","A136552-","T136553-","C136554-","G157078C","A157083C","T157101C","T157109C","T157112C","G157119C","C157126A","G157128A","G157129A","G157197A","G157200A","C157296T","C157729A","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","T178048-"],"OPG025":["D401N"],"OPG050":["R26Q"],"OPG085":["D427N"],"OPG129":["E227K"],"OPG136":["R830Q"],"OPG145":["D453N"],"OPG153":["D385-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG025: D401N; OPG050: R26Q; OPG085: D427N; OPG129: E227K; OPG136: R830Q; OPG145: D453N; OPG153: D385-; OPG197: T34-, D35-"}}},{"name":"NODE_0000057","node_attrs":{"div":504,"lineage":{"value":"A"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G51559A","C60923T","G179884A"],"OPG080":["E366K"],"OPG208":["E207K"]},"labels":{"aa":"OPG080: E366K; OPG208: E207K"}},"children":[{"name":"MT903337","node_attrs":{"div":506,"accession":"MT903337","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"lineage":{"value":"A"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/MT903337/2018-XX-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV-M2940_FCT"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-XX-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","G172784A","T181577C"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"OP535334","node_attrs":{"div":508,"accession":"OP535334","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"lineage":{"value":"A"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP535334/2018-02-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV_Nigeria_2018_5223"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-02-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T607-","C101683T","C127245T","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","G178814A","G178988A","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A196615-"],"OPG149":["S17L"]},"labels":{"aa":"OPG149: S17L"}}},{"name":"OP535326","node_attrs":{"div":510,"accession":"OP535326","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"lineage":{"value":"A"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP535326/2018-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV_Nigeria_2018_5315"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C23000T","G29826A","C109667T","A136552-","T136553-","C136554-","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","G147459A","G155644A","G177009A","C179226T","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-"],"OPG038":["G54S"],"OPG047":["R457C"],"OPG153":["D385-"],"OPG205":["E452K"]},"labels":{"aa":"OPG038: G54S; OPG047: R457C; OPG153: D385-; OPG205: E452K"}}}]},{"name":"NODE_0000063","node_attrs":{"div":503,"lineage":{"value":"A"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G37209A","G48180A","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-"],"OPG056":["S609F"]},"labels":{"aa":"OPG056: S609F"}},"children":[{"name":"OP535322","node_attrs":{"div":510,"accession":"OP535322","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"lineage":{"value":"A"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP535322/2017-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV_Nigeria_2017_2958"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-10-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G2398A","A16620-","T16621-","C16622-","G17797A","C47585T","C117119T","C135038T","G150620-","G150621-","A150622-","T150623-","A150624-","T150625-","G150626-","A150627-","T150628-","G161496A","C165497T","C194812T"],"OPG029":["D154-"],"OPG030":["L13F"],"OPG187":["R292Q"],"OPG190":["P126S"]},"labels":{"aa":"OPG029: D154-; OPG030: L13F; OPG187: R292Q; OPG190: P126S"}}},{"name":"NODE_0000064","node_attrs":{"div":507,"lineage":{"value":"A"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C8385T","G43118A","C113841T","A136552-","T136553-","C136554-","C146607T","A169763-","A169765-","A169767-","T169768-","A169769-","A169771-","A169773-","T169774-"],"OPG133":["G619E"],"OPG153":["D385-"],"OPG170":["E58K"]},"labels":{"aa":"OPG133: G619E; OPG153: D385-; OPG170: E58K"}},"children":[{"name":"OP535328","node_attrs":{"div":507,"accession":"OP535328","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"lineage":{"value":"A"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP535328/2018-03-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV_Nigeria_2018_5306"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-03-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T169721A","C169764-","G169766-","C169770-","G169772-"],"OPG197":["S18T","T32-","D33-","T34-","D35-"]},"labels":{"aa":"OPG197: S18T, T32-, D33-, T34-, D35-"}}},{"name":"NODE_0000065","node_attrs":{"div":508,"lineage":{"value":"A"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G29889A","T76087-","A89106-","-169763A","-169765A","-169767A","-169768T","-169769A","-169771A","-169773A","-169774T","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T"],"OPG047":["P436S"]},"labels":{"aa":"OPG047: P436S"}},"children":[{"name":"NODE_0000066","node_attrs":{"div":511,"lineage":{"value":"A"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-","C40251T","C63801T","T121121-","G162243A","-196616A"],"OPG058":["D62N"],"OPG083":["E306K"]},"labels":{"aa":"OPG058: D62N; OPG083: E306K"}},"children":[{"name":"OP612680","node_attrs":{"div":514,"accession":"OP612680","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"lineage":{"value":"A"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP612680/2019-04-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV/021/19"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-04-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C63264T","-89106A","T104748C","T133098-","T133099-","T133100-","T133101-","T133102-","T187080A","A187083-"],"OPG123":["D108G"]},"labels":{"aa":"OPG123: D108G"}}},{"name":"OP612684","node_attrs":{"div":514,"accession":"OP612684","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"lineage":{"value":"A"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP612684/2019-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV/046/19"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C92830T","A136543-","T136544-","C136545-","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","-173288A","-173289T","G180656A","G186423A","-196617A"],"OPG113":["S367F"],"OPG153":["D382-","D383-","D384-"],"OPG209":["D47N"],"OPG210":["E1690K"]},"labels":{"aa":"OPG113: S367F; OPG153: D382-, D383-, D384-; OPG209: D47N; OPG210: E1690K"}}}]},{"name":"NODE_0000067","node_attrs":{"div":511,"lineage":{"value":"A"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","C28164T","C87027T","G121454A"],"OPG044":["S25F"]},"labels":{"aa":"OPG044: S25F"}},"children":[{"name":"OP612678","node_attrs":{"div":515,"accession":"OP612678","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"lineage":{"value":"A"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP612678/2019-03-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV/017/19"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-03-14"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G46685A","G144659A","G165688A","T187080A","A187083-","A196614-","A196615-"],"OPG167":["S250F"]},"labels":{"aa":"OPG167: S250F"}}},{"name":"NODE_0000068","node_attrs":{"div":513,"lineage":{"value":"A"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G3531A","-76087T","T151621G","T179068A","C179226T","-196616A","-196617A"],"OPG178":["F38C"]},"labels":{"aa":"OPG178: F38C"}},"children":[{"name":"OP612676","node_attrs":{"div":513,"accession":"OP612676","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"lineage":{"value":"A"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP612676/2019-02-20"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV/013/19"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-02-20"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A19360-","A23252-","T133099-","T133100-","T133101-","A138474-","A156769-","T163332-","A173514-","A173515-","G173516-","A173517-","A173518-","G173519-","A173520-","C173521-","G173522-","A173523-","G173524-","G173525-","A173526-","C173527-","G173528-","G173529-","A173530-","G173531-","A173532-","C173533-","G173534-","G173535-","T173536-","A173537-","G173538-","A173539-","A173540-","T173541-","A173542-","A173543-","T179072A"]}}},{"name":"OP612675","node_attrs":{"div":514,"accession":"OP612675","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"lineage":{"value":"A"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP612675/2019-01-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV/007/19"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-01-30"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T4676C","-89106A","-136552A","-136553T","-136554C","C193679T"]}}}]}]}]}]}]},{"name":"NODE_0000069","node_attrs":{"div":502,"lineage":{"value":"A"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G154015A"],"OPG180":["D442N"]},"labels":{"aa":"OPG180: D442N"}},"children":[{"name":"MK783032","node_attrs":{"div":510,"accession":"MK783032","author":{"author":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J.","value":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J."},"lineage":{"value":"A"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/MK783032/2017-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MK783032"},"institution":{"value":"NCEZID/DHCPP/PRB, Centers for Disease Control & Prevention (US CDC), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-11-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-608T","C10430T","C18699T","G26002A","C134814T","C143669T","G180039A","G180827A","G189317A","-196616A"],"OPG005":["R40K"],"OPG031":["D44N"],"OPG042":["R366C"],"OPG165":["L52F"],"OPG208":["M258I"],"OPG209":["E104K"]},"labels":{"aa":"OPG005: R40K; OPG031: D44N; OPG042: R366C; OPG165: L52F; OPG208: M258I; OPG209: E104K"}}},{"name":"NODE_0000070","node_attrs":{"div":506,"lineage":{"value":"A"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C18792T","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","G149265A","C161953T","C165782T"],"OPG031":["D13N"],"OPG153":["D384-","D385-"],"OPG174":["S44L"],"OPG188":["H120Y"],"OPG190":["P221S"]},"labels":{"aa":"OPG031: D13N; OPG153: D384-, D385-; OPG174: S44L; OPG188: H120Y; OPG190: P221S"}},"children":[{"name":"OP535313","node_attrs":{"div":517,"accession":"OP535313","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"lineage":{"value":"A"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP535313/2018-01-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV_Nigeria_2018_5221"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-01-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-608T","C40281T","C85055T","G151014A","G156874T","A156875T","A156906G","T156908-","T156913A","T156937A","G157014A","T157146A","C158049A","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","-196616A"],"OPG058":["D52N"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG058: D52N; OPG197: T34-, D35-"}}},{"name":"NODE_0000071","node_attrs":{"div":517,"lineage":{"value":"A.2"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T607-","C13298T","C30636T","C34472T","C34578T","G80099A","G93387A","G114659A","G124031A","A136546-","T136547-","C136548-","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","C148529-","A148530-","T148531-","A148532-","T148533-","C148534-","A148535-","C149872T","G168205A","C177720T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A196614-","A196615-"],"OPG047":["D187N"],"OPG053":["G38E"],"OPG113":["E553K"],"OPG145":["D29N"],"OPG153":["D383-"],"OPG174":["D288-","M289-"],"OPG176":["Q22*"],"OPG205":["R689C"]},"labels":{"aa":"OPG047: D187N; OPG053: G38E; OPG113: E553K; OPG145: D29N; OPG153: D383-; OPG174: D288-, M289-; OPG176: Q22*; OPG205: R689C","clade":"A.2"}},"children":[{"name":"ON675438","node_attrs":{"div":539,"accession":"ON675438","author":{"author":"Gigante,C.M.,Griffin-Thomas,L.A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Crain,J.,Li,Y.","value":"Gigante,C.M.,Griffin-Thomas,L.A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Crain,J.,Li,Y."},"lineage":{"value":"A.2"},"country":{"value":"USA"},"strain_display":{"value":"USA/ON675438/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_VA001"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","G11332A","G12099A","C13648T","C15105T","C16227T","C29887T","C42101T","G64216A","G75614A","C117119T","C128534T","G130454A","C134442T","C142918T","G144446A","C156429T","C164832T","C168532T","G174610A","A175231-","T175232-","C175233-","G175234-","T175235-","A175236-","G175237-","T175238-","A175239-","T175240-","C175241-","A175242-","A175243-","G175244-","A175245-","T175246-","G175247-","T175248-","A175249-","A175250-","A175251-","A175252-","T175253-","A175254-","C175255-","T175256-","T175257-","A175258-","C175259-","G175260-","G175261-","T175262-","T175263-","A175264-","T175265-","A175266-","C175267-","C175268-","G175269-","T175270-","C175271-","A175272-","C175273-","A175274-","A175275-","G175276-","A175277-","C175278-","C175279-","A175280-","C175281-","A175282-","G175283-","G175284-","T175285-","T175286-","T175287-","A175288-","A175289-","A175290-","C175291-","T175292-","A175293-","A175294-","T175295-","A175296-","C175297-","T175298-","A175299-","G175300-","A175301-","T175302-","C175303-","C175304-","G175305-","A175306-","A175307-","A175308-","A175309-","T175310-","C175311-","A175312-","A175313-","C175314-","G175315-","T175316-","A175317-","A175318-","C175319-","G175320-","A175321-","T175322-","A175323-","G175324-","G175325-","A175326-","G175327-","A175328-","A175329-","C175330-","C175331-","T175332-","G175333-","C175334-","C175335-","A175336-","A175337-","T175338-","A175339-","T175340-","A175341-","A175342-","C175343-","A175344-","T175345-","G175346-","C175347-","A175348-","G175349-","T175350-","G175351-","C175352-","T175353-","G175354-","T175355-","G175356-","T175357-","C175358-","A175359-","A175360-","C175361-","G175362-","T175363-","C175364-","A175365-","T175366-","T175367-","A175368-","T175369-","T175370-","T175371-","G175372-","T175373-","C175374-","G175375-","A175376-","C175377-","G175378-","A175379-","T175380-","G175381-","T175382-","A175383-","C175384-","T175385-","G175386-","A175387-","T175388-","T175389-","G175390-","A175391-","A175392-","T175393-","G175394-","G175395-","G175396-","A175397-","A175398-","A175399-","A175400-","T175401-","C175402-","C175403-","A175404-","T175405-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A179628G","C179853T","G188544A","-196614A"],"OPG023":["R268*"],"OPG025":["D55N","M540I"],"OPG027":["D51N"],"OPG062":["S52L"],"OPG096":["D10N"],"OPG151":["E511K"],"OPG166":["D17N"],"OPG204":["E27K","I234-","V235-","V236-","S237-","R238-","C239-","K240-","I241-","L242-","T243-","V244-","I245-","P246-","S247-","Q248-","D249-","H250-","R251-","F252-","K253-","L254-","I255-","L256-","D257-","P258-","K259-","I260-","N261-","V262-","T263-","I264-","G265-","E266-","P267-","A268-","N269-","I270-","T271-","C272-","S273-","A274-","V275-","S276-","T277-","S278-","L279-","F280-","V281-","D282-","D283-","V284-","L285-","I286-","E287-","W288-","E289-","N290-","P291-","S292-"]},"labels":{"aa":"OPG023: R268*; OPG025: D55N, M540I; OPG027: D51N; OPG062: S52L; OPG096: D10N; OPG151: E511K; OPG166: D17N; OPG204: E27K, I234-, V235-, V236-, S237-, R238-, C239-, K240-, I241-, L242-, T243-, V244-, I245-, P246-, S247-, Q248-, D249-, H250-, R251-, F252-, K253-, L254-, I255-, L256-, D257-, P258-, K259-, I260-, N261-, V262-, T263-, I264-, G265-, E266-, P267-, A268-, N269-, I270-, T271-, C272-, S273-, A274-, V275-, S276-, T277-, S278-, L279-, F280-, V281-, D282-, D283-, V284-, L285-, I286-, E287-, W288-, E289-, N290-, P291-, S292-"}}},{"name":"OP612689","node_attrs":{"div":518,"accession":"OP612689","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"lineage":{"value":"A.2"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP612689/2019-12-17"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV/111/19"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-12-17"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","T133099-","G144876A","G173355-","A173356-","G173357-","G173358-","T173359-","A173360-","C173361-","G173362-","G173363-","G173364-","A173365-","T173366-","A173367-","G173368-","A173369-","A173370-","T173371-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG167":["P178S"]},"labels":{"aa":"OPG167: P178S"}}},{"name":"NODE_0000072","node_attrs":{"div":532,"lineage":{"value":"A.2.3"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G2752A","G39173A","C57284T","G61844A","C74226T","G118739A","C146223T","G148427A","G150800A","G168365A","G170317A","G172527A","C175759T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G189417A","C189474T","C194458T"],"OPG075":["R72K"],"OPG170":["D186N"],"OPG195":["E46K"],"OPG198":["D94N"],"OPG205":["A35V"]},"labels":{"aa":"OPG075: R72K; OPG170: D186N; OPG195: E46K; OPG198: D94N; OPG205: A35V","clade":"A.2.3"}},"children":[{"name":"ON676707","node_attrs":{"div":535,"accession":"ON676707","author":{"author":"Gigante,C.M.,Stringer,J.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Schulte,J.,Li,Y.","value":"Gigante,C.M.,Stringer,J.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Schulte,J.,Li,Y."},"lineage":{"value":"A.2.3"},"country":{"value":"USA"},"strain_display":{"value":"USA/ON676707/2021-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2021_TX"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2021-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C100640T","G142636A","C186104T","-196614A"]}}},{"name":"OP555515","node_attrs":{"div":545,"accession":"OP555515","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"A.2.3"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555515/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0428/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","C30669T","C45028T","G49377A","G95355A","C121320T","G136132A","-136546A","-136547T","-136548C","G142265A","C159143T","C162264T","C170573T","C180686T","C181216T","G188229A"],"OPG047":["E176K"],"OPG064":["E291K"],"OPG068":["D393N"],"OPG139":["A17T"],"OPG153":["-383D"],"OPG163":["D22N"],"OPG185":["S76F"],"OPG198":["S179L"],"OPG209":["Q57*"]},"labels":{"aa":"OPG047: E176K; OPG064: E291K; OPG068: D393N; OPG139: A17T; OPG153: -383D; OPG163: D22N; OPG185: S76F; OPG198: S179L; OPG209: Q57*"}}}]},{"name":"NODE_0000073","node_attrs":{"div":537,"lineage":{"value":"A.2.2"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","G11948A","C14790T","G21991A","G23118A","G38923A","G39515A","G56546A","G57786A","G93312A","C103019T","C112470T","C124129T","C127906T","G135303A","G145902A","C149365T","G155611A","G158424A","G162640A","G186984A"],"OPG023":["S318F"],"OPG025":["D160N"],"OPG037":["S148L"],"OPG056":["R38C"],"OPG113":["V528I"],"OPG122":["H198Y"],"OPG132":["M357I"],"OPG150":["S43L"],"OPG153":["D382-"],"OPG174":["G11R"],"OPG188":["G349S"],"OPG210":["D1877N"]},"labels":{"aa":"OPG023: S318F; OPG025: D160N; OPG037: S148L; OPG056: R38C; OPG113: V528I; OPG122: H198Y; OPG132: M357I; OPG150: S43L; OPG153: D382-; OPG174: G11R; OPG188: G349S; OPG210: D1877N","clade":"A.2.2"}},"children":[{"name":"OP422631","node_attrs":{"div":541,"accession":"OP422631","author":{"author":"Martin,F.,Anges,Y.,Benjamin,H.,Amadou,S.A.,Ousmane,F.","value":"Martin,F.,Anges,Y.,Benjamin,H.,Amadou,S.A.,Ousmane,F."},"lineage":{"value":"A.2.2"},"country":{"value":"Benin"},"strain_display":{"value":"Benin/OP422631/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV-SEN0021"},"institution":{"value":"Institut Pasteur de Dakar, Virology Department"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T4619C","C4623-","T4624-","T4625-","T4626-","T4627-","T4628-","C4629-","A4630-","T4631-","A4632-","A4633-","T4634-","T4635-","A4636-","G4637-","A4638-","G4639-","A4640-","A4641-","A4642-","A4643-","A4644-","G4645-","A4646-","T4647-","C4648-","A4649-","A4650-","G4651-","G4652-","T4653-","A4654-","T4655-","A4656-","A4657-","A4658-","A4659-","A4660-","T4661-","T4662-","A4663-","G4664-","A4665-","A4666-","G4667-","T4668-","G4669-","T4670-","T4671-","A4672-","G4673-","A4674-","C4675-","T4676-","A4677-","T4678-","A4679-","A4680-","C32643T","-136546A","-136547T","-136548C","-136549A","-136550T","-136551C","-136552A","-136553T","-136554C","A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","-148529C","-148530A","-148531T","-148532A","-148533T","-148534C","-148535A","C156429T","G172501A","T196689-"],"OPG049":["R170K"],"OPG153":["-382D","-383D","-384D","-385D"],"OPG174":["-288D","-289M"],"OPG200":["E118K"]},"labels":{"aa":"OPG049: R170K; OPG153: -382D, -383D, -384D, -385D; OPG174: -288D, -289M; OPG200: E118K"}}},{"name":"OP450997","node_attrs":{"div":544,"accession":"OP450997","author":{"author":"Gigante,C.M.,Xia,D.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y.","value":"Gigante,C.M.,Xia,D.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y."},"lineage":{"value":"A.2.2"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP450997/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_PA0016"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G451A","G20576A","C20581T","G67351A","G78259A","G94479A","C133402T","A136543-","T136544-","C136545-","C176148T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C196759T"],"OPG036":["E162K"],"OPG085":["S394F"],"OPG205":["H165Y"]},"labels":{"aa":"OPG036: E162K; OPG085: S394F; OPG205: H165Y"}}},{"name":"NODE_0000074","node_attrs":{"div":542,"lineage":{"value":"A.2.2"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C13686T","C21861T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G151112A","G174721A","C188491T"],"OPG025":["E528K"],"OPG037":["M191I"],"OPG204":["A64T"]},"labels":{"aa":"OPG025: E528K; OPG037: M191I; OPG204: A64T"}},"children":[{"name":"OP331336","node_attrs":{"div":546,"accession":"OP331336","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"A.2.2"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP331336/2022-06-29"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_UK_2022_9000166"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-29"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C27826T","G59282A","C65743A","G85356A","A136543-","T136544-","C136545-"],"OPG043":["E44K"],"OPG084":["P341H"],"OPG106":["S48F"]},"labels":{"aa":"OPG043: E44K; OPG084: P341H; OPG106: S48F"}}},{"name":"OR113690","node_attrs":{"div":552,"accession":"OR113690","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"A.2.2"},"country":{"value":"Austria"},"strain_display":{"value":"Austria/OR113690/2023-04-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMPXV/Austria/MUW1607960/2023"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-04-05"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C18102T","C52429T","C86957T","G97318A","C121394T","G129982A","-136546A","-136547T","-136548C","-136549A","-136552A","-136553T","-136554C","G146714A","C148895A","G165892A","G175471A"],"OPG031":["D243N"],"OPG108":["D35N"],"OPG117":["D424N"],"OPG170":["A22V"],"OPG174":["M167I"],"OPG204":["E314K"]},"labels":{"aa":"OPG031: D243N; OPG108: D35N; OPG117: D424N; OPG170: A22V; OPG174: M167I; OPG204: E314K"}}}]}]},{"name":"NODE_0000075","node_attrs":{"div":518,"lineage":{"value":"A.2"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C25072T","A136543-","T136544-","C136545-"],"OPG040":["R136Q"],"OPG153":["D382-"]},"labels":{"aa":"OPG040: R136Q; OPG153: D382-"}},"children":[{"name":"OP612691","node_attrs":{"div":520,"accession":"OP612691","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"lineage":{"value":"A.2"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP612691/2020-01-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV/191/20"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2020-01-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-609T","C90329T","C132520T","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG111":["S22L"]},"labels":{"aa":"OPG111: S22L"}}},{"name":"NODE_0000076","node_attrs":{"div":531,"lineage":{"value":"A.2.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G36898A","G42183A","C42903T","G50346A","C54268T","C73616T","G79406A","G105746A","A140492C","C142498T","C157737T","C161152T","A169763-","C169764-","A169765-","G169766-","A169767-","T169768-","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","C179537T","-196614A","-196615A"],"OPG062":["M79I"],"OPG063":["M262I"],"OPG069":["D121N"],"OPG102":["D108N"],"OPG160":["S195A"],"OPG197":["T32-","D33-","T34-","D35-"],"OPG208":["S91L"]},"labels":{"aa":"OPG062: M79I; OPG063: M262I; OPG069: D121N; OPG102: D108N; OPG160: S195A; OPG197: T32-, D33-, T34-, D35-; OPG208: S91L","clade":"A.2.1"}},"children":[{"name":"NODE_0000077","node_attrs":{"div":532,"lineage":{"value":"A.2.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T95936A"],"OPG116":["D192E"]},"labels":{"aa":"OPG116: D192E"}},"children":[{"name":"ON674051","node_attrs":{"div":534,"accession":"ON674051","author":{"author":"Gigante,C.M.,Lee,P.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y."},"lineage":{"value":"A.2.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/ON674051/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_FL001"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T608-","C112544T","G163540A"],"OPG132":["D333N"],"OPG189":["E70K"]},"labels":{"aa":"OPG132: D333N; OPG189: E70K"}}},{"name":"OR459777","node_attrs":{"div":540,"accession":"OR459777","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"A.2.1"},"country":{"value":"South Korea"},"strain_display":{"value":"South Korea/OR459777/2022-11-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MPXV-ROK-P004-2022"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-22"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-609T","A46522G","G52289A","G67261A","C72231T","C115379T","C135822T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G181947A","G182189A","-196616A","-196617A"],"OPG071":["T717I"],"OPG085":["S424L"],"OPG210":["D198N"]},"labels":{"aa":"OPG071: T717I; OPG085: S424L; OPG210: D198N"}}}]},{"name":"NODE_0000078","node_attrs":{"div":532,"lineage":{"value":"A.2.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C184924T","-196616A","-196617A"],"OPG210":["S1190L"]},"labels":{"aa":"OPG210: S1190L"}},"children":[{"name":"OP936000","node_attrs":{"div":541,"accession":"OP936000","author":{"author":"Nguyen,D.T.,Le,H.M.,Huynh,H.T.T.,Tang,T.C.,Le,N.H.,Nguyen,H.H.,Nghiem,N.M.,Nguyen,H.T.T.,Vo,Q.T.,Vu,T.T.K.,Nguyen,T.T.,Phan,T.V.,Nguyen,T.L.N.,Le,T.M.,Vo,Q.M.,Dinh,M.N.H.,Nguyen,P.T.,Tran,P.T.L.,Tran,T.T.T.,Pham,T.T.N.,Nguyen,T.H.,Truong,L.T.T.,Nguyen,H.N.T.,Tran,T.T.,Le,K.T.T.,Lam,Y.M.,Thwaites,G.,Thwaites,L.,Nguyen,C.V.V.,Nguyen,A.T.,Le,T.V.","value":"Nguyen,D.T.,Le,H.M.,Huynh,H.T.T.,Tang,T.C.,Le,N.H.,Nguyen,H.H.,Nghiem,N.M.,Nguyen,H.T.T.,Vo,Q.T.,Vu,T.T.K.,Nguyen,T.T.,Phan,T.V.,Nguyen,T.L.N.,Le,T.M.,Vo,Q.M.,Dinh,M.N.H.,Nguyen,P.T.,Tran,P.T.L.,Tran,T.T.T.,Pham,T.T.N.,Nguyen,T.H.,Truong,L.T.T.,Nguyen,H.N.T.,Tran,T.T.,Le,K.T.T.,Lam,Y.M.,Thwaites,G.,Thwaites,L.,Nguyen,C.V.V.,Nguyen,A.T.,Le,T.V."},"lineage":{"value":"A.2.1"},"country":{"value":"Vietnam"},"strain_display":{"value":"Vietnam/OP936000/2022-09-26"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"Mpox-HCMC-M157"},"institution":{"value":"EI group, Oxford University Clinica Research Unit"},"date":{"value":"2022-09-26"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T647-","G648-","C32252T","G51559A","A86823T","G103706A","C152033T","T167015G","A167020T","A167021-","C167022-","G167029C","A187574C"]}}},{"name":"NODE_0000079","node_attrs":{"div":533,"lineage":{"value":"A.2.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G43103A","A136540-","T136541-","C136542-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"],"OPG063":["P196S"],"OPG153":["D381-"]},"labels":{"aa":"OPG063: P196S; OPG153: D381-"}},"children":[{"name":"OR455100","node_attrs":{"div":539,"accession":"OR455100","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"A.2.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR455100/2023-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-081251/2023"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-609T","C29438T","G58696A","G120906A","G147352A","G178102A","C187942T","A192392-","A192393-","A192394-","T192395-","G192396-","A192397-","G192398-","T192399-","T192400-","A192401-","A192402-","T192403-","A192404-","G192405-"],"OPG046":["V98I"],"OPG078":["S39L"],"OPG138":["S76F"],"OPG171":["R122K"]},"labels":{"aa":"OPG046: V98I; OPG078: S39L; OPG138: S76F; OPG171: R122K"}}},{"name":"NODE_0000080","node_attrs":{"div":535,"lineage":{"value":"A.2.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G30868A","G102599A","-133098T","-133101T","-133102T","-169763A","-169764C","-169765A","-169766G","-169767A","-169768T","-169769A","-169770C","-169771A","-169772G","-169773A","-169774T"],"OPG122":["D58N"],"OPG197":["-32T","-33D","-34T","-35D"]},"labels":{"aa":"OPG122: D58N; OPG197: -32T, -33D, -34T, -35D"}},"children":[{"name":"OP331335","node_attrs":{"div":536,"accession":"OP331335","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"A.2.1"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP331335/2022-06-03"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_UK_2022_9000155"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-03"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T607-","T608-","-133099T","-133100T","-136540A","-136541T","-136542C","-136543A","-136544T","-136545C","-136546A","-136547T","-136548C","-136549A","-136550T","-136551C","-136552A","-136553T","-136554C","C164210T","-174531G","-174532A","-174533T","-174534G","-174535A","-174536A"],"OPG153":["-381D","-382D","-383D","-384D","-385D"],"OPG189":["S293L"]},"labels":{"aa":"OPG153: -381D, -382D, -383D, -384D, -385D; OPG189: S293L"}}},{"name":"OP605572","node_attrs":{"div":535,"accession":"OP605572","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"A.2.1"},"country":{"value":"Slovenia"},"strain_display":{"value":"Slovenia/OP605572/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Slovenia-MPXV-30-2022"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C165-","A196625-","T196626-","T196627-"]}}}]}]}]}]}]}]}]}]},{"name":"NODE_0000118","node_attrs":{"div":502,"lineage":{"value":"A"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A173314-","T173315-","A173316-","T173317-","C187428T"]}},"children":[{"name":"NODE_0000058","node_attrs":{"div":510,"lineage":{"value":"A.3"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G56968A","G61844A","C84008T","G96841A","C100971T","C134078T","C151050T","G188889-"],"OPG074":["S53L"],"OPG117":["D265N"],"OPG120":["E260K"]},"labels":{"aa":"OPG074: S53L; OPG117: D265N; OPG120: E260K","clade":"A.3"}},"children":[{"name":"MG693723","node_attrs":{"div":523,"accession":"MG693723","author":{"author":"Faye,O.,Pratt,C.B.,Faye,M.,Fall,G.,Chitty,J.A.,Diagne,M.M.,Wiley,M.R.,Yinka-Ogunleye,A.F.,Aruna,S.,Etebu,E.N.,Aworabhi,N.,Ogoina,D.,Numbere,W.,Mba,N.,Palacios,G.,Sall,A.A.,Ihekweazu,C.,Diagne,M.,Palacios,G.F.,Sall,A.","value":"Faye,O.,Pratt,C.B.,Faye,M.,Fall,G.,Chitty,J.A.,Diagne,M.M.,Wiley,M.R.,Yinka-Ogunleye,A.F.,Aruna,S.,Etebu,E.N.,Aworabhi,N.,Ogoina,D.,Numbere,W.,Mba,N.,Palacios,G.,Sall,A.A.,Ihekweazu,C.,Diagne,M.,Palacios,G.F.,Sall,A."},"lineage":{"value":"A.3"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/MG693723/2017-XX-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV_Nig_2017_297957"},"institution":{"value":"USAMRIID, Center for Genome Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-XX-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A8143-","G8144-","C8145-","A8146-","T8147-","A8148-","T8149-","T8150-","A8151-","A8152-","A8153-","G8154-","T8155-","A8156-","A8157-","A8158-","A8159-","T8160-","C8161-","T8162-","A8163-","G8164-","T8165-","T8166-","A8167-","C8168-","C8169-","T8170-","T8171-","G8172-","A8173-","A8174-","A8175-","A8176-","T8177-","G8178-","A8179-","A8180-","T8181-","A8182-","C8183-","A8184-","G8185-","T8186-","G8187-","G8188-","G8189-","T8190-","G8191-","G8192-","T8193-","T8194-","C8195-","C8196-","G8197-","T8198-","A8199-","T8200-","C8201-","A8202-","C8203-","C8204-","A8205-","G8206-","T8207-","A8208-","A8209-","G8210-","A8211-","A8212-","C8213-","A8214-","T8215-","A8216-","A8217-","T8218-","A8219-","G8220-","T8221-","C8222-","G8223-","A8224-","A8225-","T8226-","A8227-","C8228-","A8229-","G8230-","T8231-","A8232-","T8233-","C8234-","C8235-","G8236-","A8237-","T8238-","T8239-","G8240-","A8241-","G8242-","A8243-","T8244-","T8245-","T8246-","T8247-","G8248-","C8249-","A8250-","T8251-","A8252-","C8253-","A8254-","A8255-","T8256-","A8257-","C8258-","T8259-","A8260-","G8261-","T8262-","C8263-","T8264-","A8265-","G8266-","A8267-","A8268-","A8269-","G8270-","A8271-","A8272-","A8273-","T8274-","T8275-","T8276-","G8277-","T8278-","A8279-","A8280-","T8281-","C8282-","A8283-","T8284-","C8285-","C8286-","T8287-","C8288-","T8289-","G8290-","T8291-","G8292-","A8293-","C8294-","A8295-","G8296-","G8297-","A8298-","G8299-","T8300-","C8301-","C8302-","A8303-","T8304-","A8305-","T8306-","A8307-","T8308-","C8309-","T8310-","G8311-","T8312-","A8313-","T8314-","C8315-","A8316-","T8317-","C8318-","G8319-","T8320-","C8321-","T8322-","A8323-","G8324-","T8325-","T8326-","T8327-","T8328-","T8329-","A8330-","T8331-","C8332-","A8333-","G8334-","T8335-","G8336-","T8337-","C8338-","C8339-","T8340-","A8341-","T8342-","G8343-","C8344-","T8345-","A8346-","T8347-","A8348-","T8349-","T8350-","C8351-","C8352-","T8353-","G8354-","T8355-","T8356-","A8357-","T8358-","C8359-","A8360-","T8361-","C8362-","A8363-","T8364-","T8365-","A8366-","G8367-","T8368-","T8369-","A8370-","A8371-","T8372-","G8373-","A8374-","A8375-","A8376-","A8377-","T8378-","A8379-","A8380-","C8381-","T8382-","C8383-","T8384-","C8385-","G8386-","T8387-","G8388-","C8389-","T8390-","T8391-","C8392-","A8393-","G8394-","A8395-","A8396-","A8397-","A8398-","G8399-","T8400-","C8401-","A8402-","A8403-","A8404-","T8405-","A8406-","T8407-","T8408-","G8409-","T8410-","A8411-","T8412-","C8413-","C8414-","A8415-","T8416-","A8417-","C8418-","A8419-","T8420-","A8421-","T8422-","A8423-","T8424-","C8425-","T8426-","C8427-","C8428-","A8429-","A8430-","A8431-","A8432-","C8433-","T8434-","A8435-","T8436-","C8437-","A8438-","C8439-","T8440-","T8441-","A8442-","T8443-","A8444-","C8445-","G8446-","T8447-","T8448-","T8449-","A8450-","T8451-","C8452-","T8453-","T8454-","T8455-","A8456-","A8457-","C8458-","G8459-","A8460-","A8461-","C8462-","A8463-","T8464-","A8465-","T8466-","A8467-","C8468-","C8469-","T8470-","A8471-","G8472-","A8473-","T8474-","G8475-","G8476-","T8477-","T8478-","A8479-","T8480-","T8481-","T8482-","A8483-","C8484-","T8485-","A8486-","A8487-","C8488-","A8489-","G8490-","A8491-","C8492-","A8493-","T8494-","T8495-","T8496-","T8497-","T8498-","T8499-","C8500-","A8501-","A8502-","G8503-","A8504-","T8505-","C8506-","T8507-","A8508-","T8509-","T8510-","G8511-","A8512-","C8513-","A8514-","A8515-","T8516-","A8517-","A8518-","C8519-","T8520-","C8521-","C8522-","T8523-","A8524-","T8525-","A8526-","G8527-","T8528-","T8529-","T8530-","C8531-","C8532-","A8533-","C8534-","A8535-","T8536-","C8537-","A8538-","A8539-","C8540-","C8541-","A8542-","A8543-","G8544-","T8545-","A8546-","A8547-","T8548-","G8549-","A8550-","T8551-","C8552-","A8553-","T8554-","C8555-","T8556-","A8557-","T8558-","T8559-","G8560-","T8561-","T8562-","A8563-","T8564-","A8565-","T8566-","A8567-","A8568-","C8569-","A8570-","A8571-","T8572-","A8573-","A8574-","C8575-","A8576-","T8577-","A8578-","A8579-","C8580-","T8581-","C8582-","T8583-","T8584-","T8585-","T8586-","C8587-","C8588-","A8589-","T8590-","T8591-","T8592-","T8593-","T8594-","A8595-","T8596-","C8597-","A8598-","G8599-","T8600-","A8601-","T8602-","C8603-","T8604-","A8605-","T8606-","A8607-","T8608-","C8609-","A8610-","A8611-","C8612-","G8613-","T8614-","C8615-","G8616-","T8617-","T8618-","G8619-","T8620-","A8621-","G8622-","T8623-","G8624-","A8625-","A8626-","T8627-","A8628-","G8629-","T8630-","A8631-","G8632-","T8633-","C8634-","A8635-","T8636-","T8637-","G8638-","A8639-","T8640-","C8641-","T8642-","A8643-","T8644-","T8645-","A8646-","T8647-","A8648-","T8649-","G8650-","A8651-","A8652-","A8653-","C8654-","G8655-","G8656-","A8657-","T8658-","A8659-","T8660-","G8661-","T8662-","C8663-","T8664-","A8665-","G8666-","T8667-","T8668-","A8669-","A8670-","T8671-","A8672-","T8673-","T8674-","T8675-","T8676-","C8677-","T8678-","T8679-","T8680-","G8681-","A8682-","T8683-","T8684-","T8685-","A8686-","A8687-","A8688-","G8689-","T8690-","C8691-","T8692-","A8693-","T8694-","A8695-","G8696-","T8697-","C8698-","T8699-","T8700-","T8701-","A8702-","C8703-","A8704-","A8705-","A8706-","C8707-","A8708-","T8709-","A8710-","A8711-","T8712-","A8713-","T8714-","C8715-","C8716-","T8717-","T8718-","A8719-","T8720-","C8721-","C8722-","G8723-","A8724-","C8725-","T8726-","T8727-","T8728-","A8729-","T8730-","A8731-","T8732-","T8733-","T8734-","C8735-","C8736-","T8737-","G8738-","T8739-","A8740-","G8741-","G8742-","G8743-","T8744-","G8745-","G8746-","C8747-","A8748-","T8749-","A8750-","A8751-","T8752-","T8753-","T8754-","T8755-","A8756-","T8757-","T8758-","C8759-","T8760-","G8761-","C8762-","C8763-","T8764-","C8765-","C8766-","A8767-","C8768-","A8769-","A8770-","T8771-","C8772-","A8773-","G8774-","T8775-","G8776-","T8777-","T8778-","T8779-","C8780-","C8781-","A8782-","A8783-","A8784-","T8785-","A8786-","T8787-","A8788-","T8789-","T8790-","A8791-","C8792-","T8793-","A8794-","G8795-","A8796-","C8797-","A8798-","A8799-","T8800-","A8801-","T8802-","T8803-","C8804-","C8805-","A8806-","T8807-","A8808-","T8809-","A8810-","G8811-","T8812-","T8813-","A8814-","T8815-","T8816-","A8817-","G8818-","T8819-","T8820-","A8821-","A8822-","G8823-","G8824-","G8825-","A8826-","C8827-","C8828-","C8829-","A8830-","A8831-","T8832-","T8833-","A8834-","G8835-","A8836-","A8837-","C8838-","A8839-","C8840-","G8841-","T8842-","A8843-","C8844-","G8845-","C8846-","G8847-","C8848-","T8849-","T8850-","A8851-","T8852-","T8853-","C8854-","A8855-","T8856-","C8857-","A8858-","T8859-","T8860-","T8861-","G8862-","G8863-","A8864-","T8865-","C8866-","G8867-","T8868-","A8869-","T8870-","T8871-","T8872-","C8873-","A8874-","T8875-","A8876-","A8877-","A8878-","A8879-","G8880-","T8881-","T8882-","A8883-","T8884-","T8885-","A8886-","T8887-","G8888-","T8889-","T8890-","A8891-","T8892-","A8893-","G8894-","A8895-","T8896-","G8897-","T8898-","C8899-","A8900-","A8901-","C8902-","A8903-","C8904-","A8905-","T8906-","T8907-","C8908-","T8909-","A8910-","C8911-","A8912-","T8913-","T8914-","T8915-","T8916-","T8917-","T8918-","T8919-","A8920-","A8921-","T8922-","T8923-","G8924-","T8925-","C8926-","T8927-","A8928-","T8929-","A8930-","T8931-","A8932-","G8933-","T8934-","A8935-","T8936-","T8937-","T8938-","T8939-","T8940-","C8941-","T8942-","G8943-","A8944-","T8945-","A8946-","T8947-","T8948-","T8949-","T8950-","C8951-","T8952-","A8953-","T8954-","A8955-","A8956-","T8957-","A8958-","T8959-","C8960-","A8961-","G8962-","A8963-","A8964-","T8965-","T8966-","G8967-","T8968-","C8969-","T8970-","T8971-","C8972-","C8973-","A8974-","T8975-","A8976-","G8977-","G8978-","A8979-","A8980-","G8981-","T8982-","T8983-","G8984-","T8985-","A8986-","T8987-","A8988-","C8989-","T8990-","A8991-","T8992-","T8993-","C8994-","G8995-","G8996-","A8997-","A8998-","T8999-","C9000-","A9001-","G9002-","T9003-","T9004-","A9005-","C9006-","A9007-","T9008-","G9009-","T9010-","T9011-","T9012-","A9013-","A9014-","A9015-","T9016-","A9017-","A9018-","T9019-","T9020-","C9021-","T9022-","C9023-","T9024-","G9025-","A9026-","T9027-","G9028-","T9029-","C9030-","A9031-","T9032-","T9033-","C9034-","C9035-","T9036-","T9037-","A9038-","T9039-","A9040-","C9041-","A9042-","A9043-","T9044-","C9045-","A9046-","A9047-","A9048-","T9049-","T9050-","C9051-","A9052-","T9053-","T9054-","A9055-","T9056-","T9057-","A9058-","A9059-","A9060-","C9061-","A9062-","G9063-","T9064-","T9065-","T9066-","A9067-","A9068-","T9069-","A9070-","G9071-","T9072-","C9073-","T9074-","G9075-","T9076-","A9077-","G9078-","A9079-","C9080-","C9081-","T9082-","T9083-","T9084-","A9085-","T9086-","C9087-","G9088-","T9089-","C9090-","G9091-","T9092-","A9093-","C9094-","A9095-","T9096-","A9097-","T9098-","C9099-","C9100-","A9101-","T9102-","T9103-","G9104-","T9105-","C9106-","T9107-","T9108-","A9109-","T9110-","T9111-","A9112-","G9113-","T9114-","T9115-","A9116-","C9117-","G9118-","C9119-","T9120-","T9121-","A9122-","T9123-","T9124-","T9125-","T9126-","T9127-","A9128-","T9129-","G9130-","G9131-","G9132-","T9133-","T9134-","T9135-","T9136-","A9137-","C9138-","G9139-","T9140-","T9141-","G9142-","C9143-","T9144-","T9145-","T9146-","A9147-","T9148-","T9149-","A9150-","T9151-","A9152-","T9153-","T9154-","T9155-","T9156-","A9157-","T9158-","A9159-","A9160-","T9161-","A9162-","A9163-","T9164-","G9165-","A9166-","T9167-","T9168-","G9169-","T9170-","T9171-","T9172-","G9173-","A9174-","C9175-","A9176-","A9177-","T9178-","G9179-","T9180-","C9181-","G9182-","T9183-","A9184-","G9185-","T9186-","A9187-","T9188-","A9189-","G9190-","A9191-","T9192-","A9193-","T9194-","A9195-","T9196-","T9197-","A9198-","T9199-","T9200-","A9201-","G9202-","A9203-","G9204-","G9205-","A9206-","G9207-","G9208-","T9209-","A9210-","T9211-","A9212-","A9213-","T9214-","T9215-","A9216-","T9217-","A9218-","A9219-","A9220-","A9221-","A9222-","G9223-","T9224-","T9225-","T9226-","C9227-","T9228-","G9229-","A9230-","G9231-","T9232-","A9233-","C9234-","G9235-","A9236-","T9237-","G9238-","T9239-","T9240-","A9241-","T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","C9257-","A9258-","T9259-","T9260-","A9261-","A9262-","C9263-","A9264-","T9265-","C53702T","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","A166866-","C166867-","T166868-","G166869-","A166870-","T166871-","G166872-","A166873-","T166874-","A166875-","A166876-","T166877-","A166878-","A166879-","T166880-","G166881-","A166882-","A166883-","T166884-","T166885-","G166886-","G166887-","T166888-","G166889-","T166890-","T166891-","A166892-","A166893-","A166894-","T166895-","T166896-","T166897-","T166898-","A166899-","A166900-","A166901-","G166902-","A166903-","G166904-","T166905-","A166906-","C166907-","A166908-","C166909-","A166910-","A166911-","T166912-","T166913-","T166914-","C166915-","T166916-","A166917-","T166918-","T166919-","A166920-","T166921-","T166922-","A166923-","C166924-","A166925-","G166926-","A166927-","G166928-","T166929-","C166930-","A166931-","T166932-","G166933-","T166934-","G166935-","A166936-","C166937-","G166938-","T166939-","C166940-","G166941-","G166942-","A166943-","T166944-","T166945-","T166946-","G166947-","A166948-","T166949-","T166950-","C166951-","C166952-","A166953-","T166954-","A166955-","G166956-","A166957-","T166958-","A166959-","T166960-","A166961-","G166962-","A166963-","T166964-","G166965-","T166966-","T166967-","A166968-","T166969-","A166970-","A166971-","A166972-","C166973-","G166974-","A166975-","C166976-","T166977-","A166978-","T166979-","A166980-","A166981-","A166982-","A166983-","T166984-","T166985-","A166986-","T166987-","T166988-","G166989-","A166990-","T166991-","A166992-","T166993-","G166994-","T166995-","A166996-","T166997-","A166998-","C166999-","C168582A","C168584-","T168585-","C168586-","T168587-","G168588-","T168589-","A168590-","T168591-","T168592-","T168593-","C168594-","T168595-","G168596-","T168597-","A168598-","T168599-","A168600-","T168601-","T168602-","G168603-","T168604-","G168605-","A168606-","T168607-","C168608-","A168609-","A168610-","G168611-","A168612-","G168613-","G168614-","C168615-","G168616-","G168617-","G168618-","A168619-","G168620-","T168624G","A168626-","A168627-","A168628-","T168629-","T168630-","T168631-","G168632-","A168633-","G168634-","G168635-","A168636-","G168637-","T168638-","A168639-","T168640-","A168641-","C168642-","T168643-","C168644-","A168645-","A168646-","G168647-","A168648-","A168649-","T168650-","C168651-","A168652-","A168653-","G168654-","T168655-","G168656-","A168657-","T168658-","A168659-","T168660-","C168661-","A168662-","G168663-","T168664-","A168665-","T168666-","T168667-","A168668-","A168674-","A168675-","G168676-","T168677-","A168678-","T168679-","G168680-","A168681-","T168682-","T168683-","C168684-","A168685-","T168686-","C168687-","A168688-","T168689-","G168690-","T168691-","A168692-","T168693-","T168694-","G168695-","A168696-","T168697-","T168698-","A168699-","T168700-","G168704-","G168705-","T168706-","A168707-","T168708-","T168709-","A168710-","A168711-","T168712-","C168713-","A168714-","A168715-","A168716-","G168717-","T168718-","T168719-","T168720-","C168721-","A168722-","T168723-","G168724-","A168725-","A168726-","T168727-","T168731C","G168732A","A168734T","C168737G","G168741-","A168742-","A168743-","T168744-","A168748T","C168750G","G168755-","A168756-","T168757-","A168758-","G168759-","A168760-","G168761-","A168762-","A168763-","T168764-","C168765-","A168766-","T168767-","G168768-","C168769-","G168770-","T168771-","C168772-","A168773-","G168774-","A168775-","T168777G","C169569-","A169570-","T169571-","T169572-","T169573-","A169574-","A169575-","T169576-","A169577-","A169578-","G169579-","G169580-","A169581-","C169582-","A169583-","T169584-","T169585-","G169586-","G169587-","A169588-","T169589-","A169590-","T169591-","G169592-","T169593-","G169594-","G169595-","A169596-","A169597-","A169598-","A169599-","G169600-","T169601-","G169602-","A169603-","T169604-","G169605-","T169606-","A169607-","T169608-","G169609-","G169610-","A169611-","A169612-","G169613-","T169614-","T169615-","A169616-","G169617-","T169618-","A169619-","C169620-","A169621-","T169622-","T169623-","A169624-","T169625-","C169626-","A169627-","A169628-","C169629-","T169630-","T169631-","C169632-","T169633-","C169634-","C169635-","T169636-","T169637-","A169638-","T169639-","T169640-","G169641-","A169642-","T169643-","T169644-","G169645-","A169646-","A169647-","A169648-","A169649-","T169650-","G169651-","A169652-","A169653-","A169654-","A169655-","T169656-","A169657-","T169658-","A169659-","A169660-","A169661-","T169662-","A169663-","G169664-","T169665-","T169666-","T169667-","T169668-","T169669-","A169670-","T169671-","G169672-","T169673-","A169674-","T169675-","A169676-","G169677-","C169678-","G169679-","G169680-","T169681-","A169682-","T169683-","C169684-","T169685-","A169686-","C169687-","C169688-","C169689-","T169690-","A169691-","T169692-","A169693-","G169694-","T169695-","T169696-","T169697-","T169698-","A169699-","T169700-","T169701-","G169702-","C169703-","T169704-","T169705-","A169706-","C169707-","T169708-","A169709-","C169710-","T169711-","A169712-","A169713-","C169714-","A169715-","T169716-","G169717-","G169718-","A169719-","T169720-","T169721-","C169722-","A169723-","G169724-","A169725-","T169726-","A169727-","C169728-","A169729-","G169730-","A169731-","T169732-","A169733-","C169734-","A169735-","G169736-","A169737-","T169738-","A169739-","C169740-","A169741-","G169742-","A169743-","T169744-","A169745-","C169746-","A169747-","G169748-","A169749-","T169750-","A169751-","C169752-","A169753-","G169754-","A169755-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","T187263G","A187265-","G187266-","A187267-","A187268-","T187269-","C187270-","A187271-","T187272-","T187273-","T187274-","A187275-","T187276-","C187277-","A187278-","T187279-","A187280-","A187281-","C187282-","T187283-","A187284-","T187285-","G187286-","T187287-","T187288-","T187289-","A187290-","A187291-","T187292-","A187293-","A187294-","A187295-","T187296-","T187297-","C187298-","A187299-","T187300-","C187301-","A187302-","A187303-","C187304-","G187305-","A187306-","A187307-","T187308-","A187309-","T187310-","C187311-","G187312-","A187313-","T187314-","A187315-","A187316-","A187317-","G187318-","A187319-","C187320-","C187321-","T187322-","C187323-","T187324-","T187325-","G187326-","T187327-","A187328-","A187329-","T187330-","T187331-","C187332-","G187333-","A187334-","G187335-","T187336-","A187337-","T187338-","A187339-","G187340-","G187341-","A187342-","A187343-","G187344-","T187345-","A187346-","G187347-","T187348-","A187349-","T187350-","T187351-","A187352-","C187353-","C187354-","A187355-","T187356-","A187357-","T187358-","C187359-","A187360-","A187361-","C187362-","C187366T","A187372-","A187373-","C187374-","A187375-","A187376-","T187377-","T187378-","A187379-","C187380-","T187381-","C187382-","T187383-","A187384-","A187385-","A187386-","A187387-","C187388-","A187389-","T187390-","G187391-","A187392-","G187393-","G187394-","A187395-","T187396-","T187397-","G187398-","T187399-","A187400-","C187401-","T187402-","C187403-","C187404-","T187405-","G187406-","T187407-","C187408-","T187409-","T187410-","G187415-","G187416-","A187417-","G187418-","A187419-","T187420-","C187421-","A187422-","C187423-","T187424-","A187425-","T187426-","T187427-","T187428-","A187429-","G187430-","T187431-","C187432-","G187433-","T187434-","T187435-","G187436-","A187437-","T187438-","A187439-","A187440-","A187441-","C187442-","T187443-","A187444-","G187445-","T187446-","A187447-","A187448-","C187449-","C187450-","T187451-","C187452-","A187453-","G187454-","G187455-","T187456-","T187457-","T187458-","C187459-","T187460-","T187461-","T187462-","A187463-","C187464-","A187465-","A187466-","A187467-","C187468-","G187469-","A187470-","T187471-","A187472-","A187473-","A187474-","G187475-","T187476-","A187477-","C187478-","A187479-","A187480-","C187481-","A187482-","T187483-","C187484-","A187485-","A187486-","G187487-","A187488-","C187489-","C187490-","T187491-","C187492-","A187493-","C187494-","A187495-","A187496-","C187497-","A187498-","C187499-","A187500-","G187501-","T187502-","G187503-","C187504-","A187505-","A187506-","G187507-","A187508-","T187509-","T187510-","A187511-","A187512-","T187513-","C187514-","T187515-","A187516-","G187517-","A187518-","A187519-","A187520-","T187521-","C187522-","A187523-","A187524-","A187525-","T187526-","G187527-","T187528-","A187529-","A187530-","T187531-","T187532-","C187533-","T187534-","G187535-","G187536-","A187537-","G187538-","G187539-","C187545-","T187546-","A187547-","G187548-","A187549-","C187550-","A187551-","A187552-","C187553-","T187554-","A187555-","A187556-","C187557-","A187558-","C187559-","C187560-","C187561-","A187562-","C187563-","G187564-","G187565-","C187566-","G187567-","A187568-","A187569-","G187570-","T187571-","A187572-","T187573-","A187574-","C187575-","T187576-","T187577-","T187578-","A187579-","T187580-","G187581-","C187582-","C187583-","T187584-","C187585-","A187586-","T187587-","T187588-","C187589-","A187590-","G187591-","A187592-","A187593-","A187594-","C187595-","G187596-","G187597-","T187598-","A187599-","A187600-","C187601-","T187602-","G187603-","T187604-","A187605-","G187606-","T187607-","A187608-","G187609-","G187610-","A187611-","G187612-","A187613-","C187614-","T187615-","G187616-","T187617-","C187618-","T187619-","C187620-","T187621-","C187622-","T187623-","A187624-","A187625-","T187626-","C187627-","T187628-","C187629-","G187630-","A187631-","T187632-","G187633-","T187634-","A187635-","T187636-","A187637-","T187638-","A187639-","T187640-","A187641-","A187642-","T187643-","A187644-","T187645-","A187646-","T187647-","A187648-","C187649-","C187650-","A187651-","A187652-","T187653-","A187654-","C187655-","G187656-","G187657-","A187658-","C187659-","G187660-","C187661-","G187662-","A187663-","T187664-","A187665-","T187666-","A187667-","T187668-","T187669-","C187670-","C187671-","G187672-","A187673-","C187674-","A187675-","T187676-","G187677-","A187678-","A187679-","T187680-","G187681-","G187682-","C187683-","G187684-","T187685-","C187686-","G187687-","C187688-","T187689-","T187690-","A187691-","T187692-","C187693-","A187694-","T187695-","A187696-","T187697-","G187698-","T187699-","T187700-","A187701-","T187702-","A187703-","T187704-","C187705-","C187706-","T187707-","A187708-","A187709-","A187710-","T187711-","G187712-","T187713-","T187714-","G187715-","A187716-","T187717-","C187718-","A187719-","T187720-","A187721-","T187722-","T187723-","C187724-","C187725-","A187726-","C187727-","A187728-","A187729-","A187730-","T187731-","G187732-","A187733-","T187734-","T187735-","G187736-","T187737-","G187738-","A187739-","A187740-","C187741-","G187742-","A187743-","G187744-","A187745-","T187746-","T187747-","A187748-","A187749-","A187750-","T187751-","C187752-","A187753-","T187754-","C187755-","T187756-","A187757-","A187758-","C187759-","A187760-","A187761-","A187762-","T187763-","A187764-","A187765-","T187766-","T187767-","A187768-","G187769-","T187770-","T187771-","T187772-","T187773-","T187774-","T187775-","A187776-","T187777-","G187778-","A187779-","C187780-","A187781-","T187782-","T187783-","A187784-","A187785-","C187786-","A187787-","T187788-","A187789-","T187790-","A187791-","A187792-","T187793-","A187794-","A187795-","A187796-","T187797-","A187798-","A187799-","A187800-","T187801-","T187802-","A187803-","A187804-","T187805-","C187806-","A187807-","T187808-","T187809-","A187810-","T187811-","T187812-","G187813-","A187814-","C187815-","T187816-","T187817-","A187818-","A187819-","C187820-","G187821-","A187822-","T187823-","G187824-","A187825-","C187826-","G187827-","A187828-","A187829-","A187830-","G187831-","T187832-","T187833-","A187834-","T187835-","C187836-","A187837-","T187838-","T187839-","A187840-","T187841-","C187842-","T187843-","T187844-","A187845-","G187846-","G187847-","A187848-","T187849-","T187850-","C187851-","T187852-","T187853-","G187854-","A187855-","T187856-","T187857-","A187858-","T187859-","T187860-","A187861-","A187862-","T187863-","A187864-","C187865-","A187866-","A187867-","A187868-","T187869-","T187870-","C187871-","G187872-","T187873-","T187874-","T188117-","T188118-","A188119-","T188120-","C188121-","G188122-","T188123-","C188124-","T188125-","C188126-","C188127-","T188128-","T188129-","A188130-","A188131-","A188132-","G188133-","C188134-","T188135-","T188136-","C188137-","T188138-","G188139-","A188140-","T188141-","G188142-","G188143-","T188144-","A188145-","A188146-","C188147-","T188148-","G188149-","T188150-","G188151-","T188152-","T188153-","A188154-","C188155-","A188156-","T188157-","G188158-","T188159-","G188160-","C188161-","T188162-","C188163-","C188164-","T188165-","A188166-","A188167-","A188168-","A188169-","C188170-","A188171-","A188172-","A188173-","A188174-","T188175-","A188176-","T188177-","G188178-","G188179-","T188180-","C188181-","G188182-","T188183-","G188184-","T188185-","G188186-","T188187-","A188188-","C188189-","G188190-","G188191-","A188192-","A188193-","A188194-","G188195-","A188196-","A188197-","A188198-","G188199-","G188200-","A188201-","G188202-","A188203-","A188204-","A188205-","A188206-","T188207-","G188208-","A188209-","T188210-","A188211-","T188212-","G188213-","G188214-","A188215-","A188216-","T188217-","A188218-","C188219-","C188220-","A188221-","T188222-","T188223-","T188224-","G188225-","T188226-","A188227-","A188228-","G188229-","A188230-","A188231-","A188232-","T188233-","G188234-","T188235-","C188236-","G188237-","G188238-","A188239-","A188240-","G188241-","G188242-","G188243-","T188244-","A188245-","C188246-","T188247-","T188248-","A188249-","T188250-","T188251-","C188252-","A188253-","G188254-","A188255-","T188256-","A188257-","T188258-","T188259-","G188260-","T188261-","A188262-","T188263-","C188264-","T188265-","G188266-","A188267-","C188268-","T188269-","C188270-","T188271-","G188272-","A188273-","T188274-","C188275-","A188276-","A188277-","T188278-","G188279-","T188280-","A188281-","A188282-","A188283-","C188284-","C188285-","T188286-","A188287-","T188288-","G188289-","A188290-","C188291-","A188292-","A188293-","G188294-","A188295-","T188296-","A188297-","A188298-","G188299-","A188300-","C188301-","T188302-","T188303-","A188304-","C188305-","T188306-","C188307-","G188308-","C188309-","A188310-","T188311-","C188312-","T188313-","A188314-","C188315-","T188316-","G188317-","G188318-","A188319-","T188320-","A188321-","G188322-","A188323-","C188324-","A188325-","T188326-","A188327-","A188328-","A188329-","T188330-","A188331-","T188332-","C188333-","C188334-","T188335-","C188336-","C188337-","T188338-","C188339-","G188340-","T188341-","A188342-","A188343-","T188344-","A188345-","A188346-","T188347-","G188348-","A188349-","A188350-","A188351-","T188352-","A188353-","T188354-","A188355-","A188356-","T188357-","A188358-","T188359-","A188360-","C188361-","A188362-","C188363-","T188364-","A188365-","A188366-","T188367-","T188368-","A188369-","T188370-","T188371-","A188372-","A188373-","T188374-","A188375-","T188376-","C188377-","A188378-","A188379-","T188380-","C188381-","G188382-","A188383-","G188384-","T188385-","A188386-","T188387-","T188388-","A188389-","A188390-","C188391-","A188392-","T188393-","A188394-","T188395-","A188396-","A188397-","G188398-","T188399-","T188400-","A188401-","T188402-","T188403-","T188404-","T188405-","T188406-","A188407-","A188408-","A188409-","C188410-","C188411-","C188412-","C188413-","T188414-","T188415-","T188416-","T188417-","G188418-","G188419-","G188420-","T188421-","T188422-","C188423-","C188424-","G188425-","T188426-","C188427-","C188428-","T188429-","A188430-","A188431-","A188432-","C188433-","G188434-","G188435-","C188436-","G188437-","T188438-","T188439-","T188440-","C188441-","G188442-","G188443-","T188444-","C188445-","T188446-","G188447-","T188448-","G188449-","T188450-","C188451-","G188452-","C188453-","C188454-","A188455-","C188456-","C188457-","A188458-","T188459-","G188460-","G188461-","T188462-","C188463-","A188464-","C188465-","A188466-","C188467-","C188468-","G188469-","A188470-","G188471-","C188472-","C188473-","T188474-","C188475-","T188476-","G188477-","C188478-","G188479-","T188480-","G188481-","C188482-","T188483-","C188484-","C188485-","T188486-","C188487-","C188488-","A188489-","T188490-","C188491-","G188492-","A188493-","G188494-","G188495-","A188496-","C188497-","G188498-","A188499-","C188500-","T188501-","T188502-","C188503-","A188504-","A188505-","C188506-","T188507-","A188508-","T188509-","G188510-","A188511-","C188512-","A188513-","G188514-","C188515-","T188516-","C188517-","G188518-","G188519-","T188520-","G188521-","G188522-","C188523-","G188524-","T188525-","C188526-","T188527-","G188528-","C188529-","C188530-","A188531-","G188532-","C188533-","G188534-","T188535-","G188536-","T188537-","A188538-","C188539-","A188540-","T188541-","A188542-","C188543-","G188544-","A188545-","A188546-","T188547-","G188548-","G188549-","C188550-","A188551-","T188552-","T188553-","T188554-","C188555-","T188556-","A188557-","A188558-","G188559-","A188560-","A188561-","A188562-","A188563-","G188564-","T188565-","C188566-","T188567-","A188568-","C188569-","G188570-","G188571-","T188572-","A188573-","T188574-","C188575-","C188576-","T188577-","T188578-","T188579-","C188580-","T188581-","A188582-","C188583-","A188584-","A188585-","T188586-","T188587-","T188588-","C188589-","C188590-","T188591-","T188592-","T188593-","A188594-","A188595-","C188596-","A188597-","A188598-","C188599-","G188600-","G188601-","C188602-","A188603-","A188604-","C188605-","A188606-","G188607-","C188608-","T188609-","G188610-","C188611-","A188612-","G188613-","T188614-","A188615-","T188616-","T188617-","T188618-","T188619-","T188620-","A188621-","T188622-","A188623-","C188624-","T188625-","T188626-","T188627-","G188628-","A188629-","A188630-","T188631-","G188632-","C188633-","A188634-","T188635-","C188636-","G188637-","G188638-","A188639-","C188640-","A188641-","T188642-","T188643-","T188644-","A188645-","T188646-","A188647-","C188648-","A188649-","A188650-","G188651-","G188652-","G188653-","A188654-","G188655-","T188656-","C188657-","C188658-","T188659-","G188660-","T188661-","T188662-","C188663-","T188664-","A188665-","A188666-","T188667-","A188668-","T188669-","T188670-","G188671-","G188672-","C188673-","A188674-","T188675-","C188676-","A188677-","A188678-","T188679-","G188680-","T188681-","T188682-","C188683-","G188684-","G188685-","A188686-","T188687-","C188688-","T188689-","A188690-","T188691-","A188692-","G188693-","G188694-","C188695-","T188696-","T188697-","G188698-","A188699-","T188700-","T188701-","T188702-","T188703-","C188704-","G188705-","C188706-","A188707-","T188708-","T188709-","G188710-","A188711-","C188712-","T188713-","T188714-","T188715-","A188716-","C188717-","A188718-","C188719-","A188720-","G188721-","A188722-","C188723-","A188724-","T188725-","G188726-","A188727-","A188728-","C188729-","A188730-","T188731-","C188732-","C188733-","C188734-","C188735-","T188736-","G188737-","A188738-","A188739-","T188740-","C188741-","T188742-","G188743-","T188744-","A188745-","C188746-","A188747-","T188748-","A188749-","C188750-","T188751-","T188752-","T188753-","G188754-","T188755-","G188756-","G188757-","A188758-","T188759-","T188760-","T188761-","A188762-","C188763-","A188764-","C188765-","T188766-","G188767-","T188768-","T188769-","A188770-","G188771-","A188772-","A188773-","T188774-","C188775-","T188776-","C188777-","T188778-","A188779-","A188780-","C188781-","G188782-","C188783-","T188784-","G188785-","G188786-","C188787-","C188788-","T188789-","C188790-","T188791-","G188792-","T188793-","T188794-","G188795-","T188796-","T188797-","A188798-","C188799-","T188800-","T188801-","T188802-","C188803-","T188804-","A188805-","T188806-","G188807-","A188808-","T188809-","G188810-","C188811-","A188812-","C188813-","G188814-","T188815-","A188816-","T188817-","C188818-","G188819-","T188820-","T188821-","A188822-","T188823-","G188824-","C188825-","A188826-","A188827-","G188828-","C188829-","T188830-","T188831-","T188832-","C188833-","A188834-","T188835-","G188836-","T188837-","T188838-","G188839-","A188840-","C188841-","T188842-","A188843-","C188844-","T188845-","G188846-","C188847-","A188848-","G188849-","T188850-","G188851-","T188852-","T188853-","T188854-","C188855-","T188856-","T188857-","G188858-","C188859-","T188860-","C188861-","T188862-","G188863-","A188864-","C188865-","T188866-","A188867-","C188868-","A188869-","T188870-","A188871-","T188872-","A188873-","C188874-","T188875-","C188876-","T188877-","A188878-","C188879-","A188880-","A188881-","T188882-","C188883-","A188884-","A188885-","A188886-","G188887-","A188888-","A188890-","G188891-","A188892-","T188893-","T188894-","T188895-","C188896-","A188897-","G188898-","T188899-","A188900-","A188901-","A188902-","C188903-","T188904-","T188905-","G188906-","T188907-","A188908-","A188909-","C188910-","A188911-","G188912-","G188913-","A188914-","T188915-","T188916-","G188917-","T188918-","T188919-","T188920-","G188921-","C188922-","T188923-","G188924-","C188925-","T188926-","T188927-","T188928-","C188929-","T188930-","G188931-","G188932-","A188933-","T188934-","T188935-","T188936-","T188937-","A188938-","A188939-","T188940-","T188941-","T188942-","T188943-","G188944-","T188945-","C188946-","A188947-","G188948-","G188949-","A188950-","G188951-","T188952-","C188953-","T188954-","T188955-","G188956-","A188957-","G188958-","G188959-","A188960-","T188961-","A188962-","A188963-","A188964-","G188965-","T188966-","T188967-","T188968-","A188969-","A188970-","A188971-","A188972-","T188973-","A188974-","G188975-","A188976-","A188977-","T188978-","T188979-","A188980-","A188981-","T188982-","A188983-","A188984-","A188985-","G188986-","A188987-","A188988-","C188989-","A188990-","T188991-","A188992-","T188993-","A188994-","G188995-","G188996-","T188997-","C188998-","A188999-","T189000-","T189001-","T189002-","T189003-","T189004-","T189005-","A189006-","A189007-","A189008-","C189009-","A189010-","T189011-","G189012-","G189013-","A189014-","T189015-","A189016-","G189017-","A189018-","A189019-","A189020-","C189021-","C189022-","A189023-","A189024-","G189025-","T190132-","A190133-","T190134-","T190135-","A190136-","A190137-","T190138-","G190139-","G190140-","A190141-","T190142-","A190143-","T190144-","A190145-","T190146-","A190147-","G190148-","A190149-","T190150-","A190151-","A190152-","C190153-","G190154-","C190155-","A190156-","A190157-","T190158-","A190159-","G190160-","G190161-","G190162-","A190163-","C190164-","T190165-","A190166-","A190167-","T190168-","A190169-","G190170-","T190171-","A190172-","T190173-","T190174-","G190175-","T190176-","A190177-","A190178-","A190179-","A190180-","G190181-","A190182-","T190183-","A190184-","T190185-","G190345A"],"OPG071":["R246Q"],"OPG192":["T46-","D47-","D48-","N49-","N50-","E51-","L52-","V53-","L54-","N55-","F56-","K57-","E58-","Y59-","T60-","I61-","S62-","I63-","I64-","T65-","E66-","S67-","C68-","D69-","V70-","G71-","F72-","D73-","S74-","I75-","D76-","I77-","D78-","V79-","I80-","N81-","D82-","Y83-","K84-","I85-","I86-","D87-","M88-","Y89-","T90-"],"OPG195":["T118N","L119-","C120-","I121-","S122-","V123-","Y124-","C125-","D126-","Q127-","E128-","A129-","G130-","D131-","I172-","L210-","K211-","S212-","K213-","A214-","L215-","H216-"]},"labels":{"aa":"OPG071: R246Q; OPG192: T46-, D47-, D48-, N49-, N50-, E51-, L52-, V53-, L54-, N55-, F56-, K57-, E58-, Y59-, T60-, I61-, S62-, I63-, I64-, T65-, E66-, S67-, C68-, D69-, V70-, G71-, F72-, D73-, S74-, I75-, D76-, I77-, D78-, V79-, I80-, N81-, D82-, Y83-, K84-, I85-, I86-, D87-, M88-, Y89-, T90-; OPG195: T118N, L119-, C120-, I121-, S122-, V123-, Y124-, C125-, D126-, Q127-, E128-, A129-, G130-, D131-, I172-, L210-, K211-, S212-, K213-, A214-, L215-, H216-"}}},{"name":"NODE_0000059","node_attrs":{"div":515,"lineage":{"value":"A.3"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C23353T","C51809T","G69678A","C125492T","C128174T","-188889A"],"OPG039":["D256N"],"OPG071":["R877Q"],"OPG146":["D50N"]},"labels":{"aa":"OPG039: D256N; OPG071: R877Q; OPG146: D50N"}},"children":[{"name":"NODE_0000060","node_attrs":{"div":516,"lineage":{"value":"A.3"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T27971C","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","-173314A","-173315T","-173316A","-173317T"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}},"children":[{"name":"MK783033","node_attrs":{"div":526,"accession":"MK783033","author":{"author":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J.","value":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J."},"lineage":{"value":"A.3"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/MK783033/2017-10-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MK783033"},"institution":{"value":"CDC, NCEZID/DHCPP/PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-10-09"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-608T","C25731T","C25768T","C26020T","A56968G","G102267T","C117099T","G129583A","C155707T","G161701A","T187428C"],"OPG042":["D360N"],"OPG074":["L53S"],"OPG121":["G160C"],"OPG136":["R830Q"],"OPG188":["V36I"]},"labels":{"aa":"OPG042: D360N; OPG074: L53S; OPG121: G160C; OPG136: R830Q; OPG188: V36I"}}},{"name":"OP535323","node_attrs":{"div":516,"accession":"OP535323","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"lineage":{"value":"A.3"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP535323/2017-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV_Nigeria_2017_2948"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-10-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000061","node_attrs":{"div":520,"lineage":{"value":"A.3"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T607-","C92053T","C123000T","C146052T","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","C150831T","C151305T"],"OPG113":["S108L"],"OPG143":["E106K"]},"labels":{"aa":"OPG113: S108L; OPG143: E106K"}},"children":[{"name":"OP612677","node_attrs":{"div":523,"accession":"OP612677","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"lineage":{"value":"A.3"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP612677/2019-03-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV/015/19"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-03-12"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C56351T","G74032A","T76087-","A89106-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","G190782A"],"OPG016":["E125K"],"OPG074":["E259K"],"OPG094":["A85T"]},"labels":{"aa":"OPG016: E125K; OPG074: E259K; OPG094: A85T"}}},{"name":"NODE_0000062","node_attrs":{"div":549,"lineage":{"value":"A.3"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","C2930T","C18493T","C18908T","G21898A","G23626A","C25254T","C29199T","G36901A","G44085A","G63034A","G75099A","G75144A","G76509A","C87659T","G115332A","C115572T","G122627A","C128771T","C140739T","A149394-","G151519T","G151875A","C160008T","C160312T","G165130A","G168862A","-173314A","-173315T","-173316A","-173317T","G174491A","G176289A","G176366A","C177703T","G194280A","A196614-","A196615-"],"OPG003":["E560K"],"OPG003_dup":["E560K"],"OPG037":["S179L"],"OPG039":["H165Y"],"OPG045":["E22K"],"OPG064":["S605L"],"OPG082":["S140L"],"OPG097":["H123Y"],"OPG109":["E597K"],"OPG133":["R42Q","S122F"],"OPG143":["T230M"],"OPG178":["G4V","D123N"],"OPG205":["A212T","M237I","S683L"]},"labels":{"aa":"OPG003: E560K; OPG003_dup: E560K; OPG037: S179L; OPG039: H165Y; OPG045: E22K; OPG064: S605L; OPG082: S140L; OPG097: H123Y; OPG109: E597K; OPG133: R42Q, S122F; OPG143: T230M; OPG178: G4V, D123N; OPG205: A212T, M237I, S683L"}},"children":[{"name":"OP413718","node_attrs":{"div":549,"accession":"OP413718","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"A.3"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP413718/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"9000360"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T133171-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"]}}},{"name":"OP536812","node_attrs":{"div":549,"accession":"OP536812","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"A.3"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP536812/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"9000450"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000081","node_attrs":{"div":514,"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C23564T","C72362T","C83326T","G87230A","G87297A","G91728A","C119296T","C121320T","G125249A","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","G148412A","C164832T","C168120T","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-"],"OPG092":["D196N"],"OPG105":["S734L"],"OPG109":["H740Y"],"OPG136":["D98N"],"OPG139":["A17T"],"OPG145":["E435K"],"OPG193":["L263F"]},"labels":{"aa":"OPG092: D196N; OPG105: S734L; OPG109: H740Y; OPG136: D98N; OPG139: A17T; OPG145: E435K; OPG193: L263F","clade":"A.1"}},"children":[{"name":"MT903343","node_attrs":{"div":517,"accession":"MT903343","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"lineage":{"value":"A.1"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/MT903343/2018-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV-UK_P1"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-608T","G28838A","G92349A","-173314A","-173315T","-173316A","-173317T","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","G188494A","-196616A"],"OPG045":["A142V"],"OPG113":["E207K"]},"labels":{"aa":"OPG045: A142V; OPG113: E207K"}}},{"name":"MN648051","node_attrs":{"div":518,"accession":"MN648051","author":{"author":"Cohen Gihon,I.,Israeli,O.,Shifman,O.,Erez,N.,Melamed,S.,Paran,N.,Beth-Din,A.,Zvi,A.","value":"Cohen Gihon,I.,Israeli,O.,Shifman,O.,Erez,N.,Melamed,S.,Paran,N.,Beth-Din,A.,Zvi,A."},"lineage":{"value":"A.1"},"country":{"value":"Israel"},"strain_display":{"value":"Israel/MN648051/2018-10-04"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MN648051"},"institution":{"value":"Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-10-04"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T607-","C8772T","C91363T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A147593T","G150568A","G177273A","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A196615-"],"OPG172":["E56V"],"OPG205":["D540N"]},"labels":{"aa":"OPG172: E56V; OPG205: D540N"}}},{"name":"MT903341","node_attrs":{"div":516,"accession":"MT903341","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"lineage":{"value":"A.1"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/MT903341/2018-08-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV-M5320_M15_Bayelsa"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-08-14"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-608T","G3153-","A3154-","T3155-","T3156-","C3157-","G3158-","A3159-","A3160-","T3161-","C3162-","T3163-","C3164-","T3165-","T3166-","T3167-","G3168-","A3169-","G3170-","G3171-","A3172-","G3173-","A3174-","C3175-","T3176-","T3177-","A3178-","T3179-","G3180-","T3181-","C3182-","A3183-","C3184-","G3185-","A3186-","C3187-","T3188-","A3189-","C3190-","A3191-","T3192-","T3193-","T3194-","T3195-","T3196-","C3197-","G3198-","A3199-","T3200-","G3201-","A3202-","T3203-","G3204-","G3205-","A3206-","A3207-","T3208-","C3209-","T3210-","A3211-","T3212-","C3213-","T3214-","T3215-","A3216-","T3217-","C3218-","G3219-","A3220-","A3221-","T3222-","G3223-","A3224-","T3225-","A3226-","T3227-","A3228-","T3229-","T3230-","T3231-","T3232-","T3233-","C3234-","A3235-","T3236-","A3237-","A3238-","A3239-","T3240-","A3241-","C3242-","A3243-","C3244-","T3245-","T3246-","T3247-","T3248-","A3249-","T3250-","A3251-","G3252-","T3253-","C3254-","C3255-","T3256-","C3257-","G3258-","T3259-","T3260-","T3261-","A3262-","A3263-","A3264-","C3265-","A3266-","G3267-","A3268-","A3269-","T3270-","T3271-","T3272-","A3273-","G3274-","T3275-","A3276-","T3277-","G3278-","T3279-","A3280-","G3281-","T3282-","T3283-","C3284-","C3285-","G3286-","C3287-","A3288-","A3289-","A3290-","T3291-","G3292-","A3293-","C3294-","T3295-","C3296-","G3297-","T3298-","C3299-","C3300-","C3301-","T3302-","T3303-","A3304-","A3305-","T3306-","A3307-","G3308-","G3309-","C3310-","A3311-","G3312-","T3313-","A3314-","G3315-","G3316-","C3317-","T3318-","A3319-","T3320-","T3321-","A3322-","T3323-","C3324-","T3325-","T3326-","C3327-","T3328-","T3329-","T3330-","A3331-","C3332-","G3333-","T3334-","A3335-","G3336-","T3337-","G3338-","A3339-","T3340-","C3341-","G3342-","T3343-","C3344-","G3345-","T3346-","A3347-","G3348-","G3349-","G3350-","A3351-","G3352-","A3353-","G3354-","A3355-","A3356-","C3357-","T3358-","C3359-","C3360-","G3361-","A3362-","C3363-","A3364-","T3365-","C3366-","T3367-","T3368-","G3369-","T3370-","A3371-","G3372-","A3373-","A3374-","C3375-","A3376-","A3377-","C3378-","G3379-","A3380-","T3381-","T3382-","T3383-","A3384-","A3385-","T3386-","C3387-","A3388-","T3389-","A3390-","G3391-","G3392-","T3393-","A3394-","G3395-","A3396-","G3397-","A3398-","T3399-","A3400-","C3401-","T3402-","T3403-","T3404-","C3405-","A3406-","G3407-","T3408-","C3409-","T3410-","G3411-","T3412-","G3413-","G3414-","T3415-","G3416-","G3417-","A3418-","T3419-","A3420-","A3421-","T3422-","G3423-","T3424-","C3425-","A3426-","T3427-","T3428-","A3429-","A3430-","C3431-","G3432-","A3433-","C3434-","A3435-","T3436-","C3437-","C3438-","G3439-","C3440-","C3441-","T3442-","T3443-","G3444-","T3445-","A3446-","T3447-","A3448-","T3449-","A3450-","A3451-","T3452-","G3453-","T3454-","T3455-","T3456-","C3457-","T3458-","G3459-","T3460-","T3461-","T3462-","T3463-","C3464-","A3465-","A3466-","A3467-","C3468-","A3469-","C3470-","C3471-","A3472-","A3473-","G3474-","T3475-","C3476-","G3477-","A3478-","A3479-","T3480-","A3481-","C3482-","T3483-","G3484-","T3485-","C3486-","T3487-","T3488-","A3489-","T3490-","C3491-","G3492-","T3493-","C3494-","T3495-","T3496-","T3497-","A3498-","G3499-","T3500-","C3501-","G3502-","G3503-","A3504-","A3505-","G3506-","G3507-","T3508-","T3509-","G3510-","A3511-","T3512-","G3513-","T3514-","C3515-","G3516-","T3517-","A3518-","T3519-","C3520-","C3521-","G3522-","A3523-","T3524-","G3525-","T3526-","A3527-","T3528-","A3529-","C3530-","G3531-","A3532-","G3533-","G3534-","T3535-","A3536-","T3537-","G3538-","A3539-","G3540-","G3541-","C3542-","A3543-","A3544-","C3545-","A3546-","T3547-","T3548-","G3549-","T3550-","T3551-","A3552-","T3553-","T3554-","G3555-","C3556-","A3557-","A3558-","T3559-","T3560-","C3561-","T3562-","G3563-","G3564-","A3565-","A3566-","G3567-","G3568-","C3569-","G3570-","G3571-","T3572-","A3573-","T3574-","G3575-","A3576-","A3577-","G3578-","A3579-","G3580-","G3581-","A3582-","G3583-","T3584-","C3585-","A3586-","T3587-","T3588-","G3589-","T3590-","A3591-","T3592-","T3593-","A3594-","T3595-","A3596-","G3597-","T3598-","A3599-","T3600-","T3601-","C3602-","G3603-","T3604-","C3605-","T3606-","T3607-","T3608-","C3609-","T3610-","G3611-","A3612-","A3613-","T3614-","G3615-","T3616-","C3617-","G3618-","A3619-","A3620-","T3621-","C3622-","T3623-","A3624-","T3625-","C3626-","T3627-","A3628-","G3629-","T3630-","A3631-","G3632-","A3633-","T3634-","A3635-","C3636-","C3637-","G3638-","T3639-","A3640-","G3641-","T3642-","A3643-","T3644-","A3645-","T3646-","T3647-","G3648-","A3649-","G3650-","A3651-","G3652-","A3653-","G3654-","C3655-","G3656-","A3657-","C3658-","T3659-","T3660-","C3661-","C3662-","A3663-","T3664-","A3665-","T3666-","C3667-","C3668-","T3669-","T3670-","G3671-","A3672-","T3673-","T3674-","A3675-","T3676-","G3677-","T3678-","T3679-","T3680-","T3681-","A3682-","T3683-","G3684-","A3685-","A3686-","T3687-","A3688-","G3689-","A3690-","T3691-","A3692-","A3693-","A3694-","G3695-","T3696-","A3697-","G3698-","A3699-","T3700-","G3701-","T3702-","T3703-","G3704-","T3705-","C3706-","C3707-","T3708-","T3709-","C3710-","T3711-","T3712-","C3713-","C3714-","T3715-","T3716-","T3717-","T3718-","G3719-","T3720-","A3721-","A3722-","T3723-","T3724-","T3725-","C3726-","C3727-","C3728-","G3729-","T3730-","A3731-","T3732-","T3733-","T3734-","T3735-","T3736-","G3737-","T3738-","T3739-","C3740-","G3741-","T3742-","G3743-","C3744-","C3745-","A3746-","A3747-","T3748-","T3749-","G3750-","A3751-","G3752-","T3753-","A3754-","A3755-","C3756-","A3757-","T3758-","T3759-","A3760-","T3761-","G3762-","A3763-","G3764-","A3765-","A3766-","T3767-","A3768-","T3769-","G3770-","A3771-","C3772-","C3773-","T3774-","G3775-","T3776-","T3777-","G3778-","C3779-","A3780-","C3781-","A3782-","A3783-","T3784-","C3785-","G3786-","T3787-","T3788-","C3789-","T3790-","T3791-","T3792-","A3793-","T3794-","G3795-","T3796-","A3797-","T3798-","T3799-","C3800-","C3801-","A3802-","T3803-","G3804-","A3805-","T3806-","G3807-","G3808-","G3809-","T3810-","G3811-","T3812-","A3813-","C3814-","A3815-","A3816-","T3817-","C3818-","A3819-","A3820-","G3821-","A3822-","T3823-","T3824-","A3825-","T3826-","T3827-","A3828-","C3829-","G3830-","T3831-","A3832-","T3833-","C3834-","C3835-","T3836-","C3837-","G3838-","T3839-","A3840-","T3841-","C3842-","G3843-","G3844-","C3845-","T3846-","C3847-","C3848-","T3849-","C3850-","G3851-","A3852-","G3853-","A3854-","T3855-","A3856-","A3857-","A3858-","A3859-","G3860-","A3861-","G3862-","C3863-","A3864-","T3865-","A3866-","C3867-","A3868-","C3869-","C3870-","A3871-","C3872-","A3873-","C3874-","G3875-","A3876-","G3877-","G3878-","A3879-","C3880-","T3881-","A3882-","T3883-","G3884-","T3885-","T3886-","T3887-","G3888-","G3889-","T3890-","A3891-","T3892-","A3893-","C3894-","T3895-","G3896-","T3897-","T3898-","G3899-","A3900-","A3901-","G3902-","G3903-","T3904-","A3905-","A3906-","G3907-","T3908-","G3909-","T3910-","G3911-","T3912-","A3913-","A3914-","C3915-","G3916-","G3917-","C3918-","G3919-","T3920-","A3921-","T3922-","T3923-","T3924-","C3925-","C3926-","G3927-","A3928-","T3929-","T3930-","T3931-","T3932-","C3933-","G3934-","T3935-","A3936-","A3937-","C3938-","C3939-","G3940-","C3941-","G3942-","T3943-","T3944-","A3945-","A3946-","T3947-","G3948-","T3949-","T3950-","T3951-","G3952-","C3953-","T3954-","C3955-","C3956-","A3957-","T3958-","G3959-","A3960-","T3961-","C3962-","T3963-","A3964-","T3965-","T3966-","A3967-","T3968-","C3969-","G3970-","C3971-","G3972-","T3973-","A3974-","G3975-","A3976-","T3977-","G3978-","A3979-","A3980-","T3981-","C3982-","G3983-","C3984-","T3985-","T3986-","C3987-","T3988-","C3989-","A3990-","G3991-","C3992-","T3993-","C3994-","G3995-","C3996-","A3997-","T3998-","C3999-","T4000-","T4001-","A4002-","G4003-","T4004-","G4005-","T4006-","G4007-","A4008-","C4009-","T4010-","C4011-","T4012-","T4013-","T4014-","G4015-","A4016-","C4017-","T4018-","T4019-","G4020-","T4021-","A4022-","A4023-","T4024-","A4025-","A4026-","T4027-","T4028-","G4029-","C4030-","T4031-","T4032-","T4033-","C4034-","G4035-","T4036-","G4037-","G4038-","A4039-","A4040-","C4041-","G4042-","C4043-","G4044-","G4045-","A4046-","T4047-","A4048-","T4049-","G4050-","T4051-","G4052-","T4053-","T4054-","T4055-","A4056-","C4057-","A4058-","G4059-","T4060-","A4061-","G4062-","T4063-","A4064-","A4065-","T4066-","G4067-","A4068-","A4069-","G4070-","A4071-","G4072-","A4073-","A4074-","G4075-","T4076-","G4077-","A4078-","G4079-","T4080-","C4081-","C4082-","A4083-","T4084-","C4085-","C4086-","T4087-","C4088-","A4089-","T4090-","C4091-","G4092-","A4093-","C4094-","G4095-","C4096-","A4097-","A4098-","T4099-","T4100-","A4101-","G4102-","G4103-","G4104-","T4105-","C4106-","A4107-","G4108-","A4109-","T4110-","C4111-","C4112-","T4113-","T4114-","T4115-","A4116-","G4117-","T4118-","C4119-","A4120-","A4121-","T4122-","A4123-","A4124-","T4125-","T4126-","T4127-","G4128-","T4129-","A4130-","C4131-","A4132-","G4133-","A4134-","A4135-","C4136-","G4137-","T4138-","A4139-","A4140-","T4141-","A4142-","G4143-","T4144-","T4145-","T4146-","A4147-","A4148-","G4149-","C4150-","T4151-","C4152-","C4153-","C4154-","A4155-","T4156-","T4157-","G4158-","A4159-","A4160-","T4161-","T4162-","T4163-","A4164-","T4165-","A4166-","T4167-","C4168-","T4169-","A4170-","A4171-","G4172-","A4173-","T4174-","A4175-","A4176-","C4177-","A4178-","C4179-","A4180-","G4181-","C4182-","A4183-","A4184-","T4185-","A4186-","G4187-","A4188-","T4189-","C4190-","G4191-","G4192-","A4193-","T4194-","G4195-","A4196-","T4197-","T4198-","T4199-","A4200-","C4201-","T4202-","A4203-","A4204-","A4205-","G4206-","T4207-","C4208-","A4209-","T4210-","C4211-","A4212-","A4213-","T4214-","G4215-","G4216-","G4217-","G4218-","T4219-","C4220-","C4221-","G4222-","T4223-","T4224-","A4225-","G4226-","T4227-","A4228-","T4229-","A4230-","T4231-","C4232-","A4233-","A4234-","A4235-","G4236-","A4237-","T4238-","C4239-","T4240-","T4241-","G4242-","T4243-","T4244-","A4245-","T4246-","C4247-","G4248-","A4249-","T4250-","T4251-","G4252-","A4253-","T4254-","A4255-","G4256-","T4257-","G4258-","A4259-","A4260-","T4261-","G4262-","A4263-","A4264-","T4265-","C4266-","A4267-","G4268-","A4269-","T4270-","A4271-","G4272-","T4273-","G4274-","G4275-","T4276-","G4277-","T4278-","A4279-","G4280-","A4281-","G4282-","G4283-","A4284-","A4285-","T4286-","A4287-","T4288-","G4289-","T4290-","C4291-","C4292-","T4293-","T4294-","T4295-","T4296-","T4297-","T4298-","A4299-","T4300-","C4301-","C4302-","T4303-","T4304-","G4305-","C4306-","T4307-","A4308-","T4309-","C4310-","A4311-","A4312-","A4313-","G4314-","T4315-","T4316-","A4317-","C4318-","G4319-","C4320-","A4321-","T4322-","G4323-","C4324-","C4325-","G4326-","T4327-","G4328-","G4329-","C4330-","G4331-","T4332-","A4333-","A4334-","C4335-","A4336-","A4337-","T4338-","A4339-","T4340-","C4341-","T4342-","T4343-","T4344-","A4345-","A4346-","T4347-","A4348-","C4349-","A4350-","G4351-","A4352-","T4353-","G4354-","G4355-","A4356-","T4357-","T4358-","A4359-","A4360-","A4361-","T4362-","C4363-","G4364-","T4365-","G4366-","T4367-","A4368-","T4369-","T4370-","C4371-","A4372-","T4373-","C4374-","G4375-","T4376-","A4377-","T4378-","A4379-","G4380-","C4381-","A4382-","A4383-","T4384-","G4385-","T4386-","A4387-","A4388-","T4389-","G4390-","G4391-","A4392-","G4393-","A4394-","G4395-","T4396-","T4397-","A4398-","C4399-","C4400-","A4401-","C4402-","A4403-","T4404-","T4405-","T4406-","T4407-","A4408-","G4409-","T4410-","C4411-","G4412-","T4413-","T4414-","T4415-","A4416-","T4417-","T4418-","C4419-","A4420-","G4421-","A4422-","T4423-","C4424-","G4425-","C4426-","A4427-","G4428-","T4429-","G4430-","T4431-","T4432-","T4433-","A4434-","A4435-","T4436-","A4437-","A4438-","C4439-","T4440-","A4441-","A4442-","T4443-","T4444-","T4445-","A4446-","A4447-","A4448-","C4449-","A4450-","G4451-","A4452-","T4453-","G4454-","A4455-","G4456-","A4457-","T4458-","G4459-","A4460-","T4461-","A4462-","T4463-","A4464-","T4465-","C4466-","C4467-","A4468-","C4469-","A4470-","T4471-","C4472-","A4473-","A4474-","A4475-","G4476-","A4477-","A4478-","T4479-","G4480-","C4481-","G4482-","A4483-","G4484-","A4485-","T4486-","A4487-","C4488-","A4489-","T4490-","A4491-","T4492-","G4493-","A4494-","C4495-","A4496-","G4497-","A4498-","C4499-","A4500-","T4501-","T4502-","A4503-","T4504-","T4505-","G4506-","A4507-","C4508-","A4509-","G4510-","A4511-","A4512-","A4513-","T4514-","G4515-","T4516-","G4517-","A4518-","C4519-","C4520-","T4521-","T4522-","C4523-","A4524-","T4525-","T4526-","A4527-","T4528-","C4529-","A4530-","C4531-","C4532-","G4533-","T4534-","C4535-","G4536-","T4537-","C4538-","C4539-","A4540-","T4541-","A4542-","A4543-","A4544-","T4545-","G4546-","C4547-","G4548-","T4549-","T4550-","A4551-","G4552-","G4553-","T4554-","A4555-","C4556-","G4557-","T4558-","A4559-","C4560-","C4561-","A4562-","C4563-","A4564-","T4565-","A4566-","C4567-","T4568-","A4569-","T4570-","C4571-","G4572-","T4573-","T4574-","A4575-","A4576-","C4577-","G4578-","A4579-","T4580-","G4581-","C4582-","G4583-","C4584-","A4585-","C4586-","A4587-","A4588-","T4589-","C4590-","T4591-","C4592-","G4593-","T4594-","C4595-","C4596-","A4597-","T4598-","T4599-","T4600-","C4601-","A4602-","T4603-","C4604-","C4605-","A4606-","T4607-","C4608-","T4609-","T4610-","C4611-","A4612-","T4613-","A4614-","A4615-","T4616-","G4617-","A4618-","T4619-","T4620-","T4621-","A4622-","C4623-","T4624-","T4625-","T4626-","T4627-","T4628-","C4629-","A4630-","T4631-","A4632-","A4633-","T4634-","T4635-","A4636-","G4637-","A4638-","G4639-","A4640-","A4641-","A4642-","A4643-","A4644-","G4645-","A4646-","T4647-","C4648-","A4649-","A4650-","G4651-","G4652-","T4653-","A4654-","T4655-","A4656-","A4657-","A4658-","A4659-","A4660-","T4661-","T4662-","A4663-","G4664-","A4665-","A4666-","G4667-","T4668-","G4669-","T4670-","T4671-","A4672-","G4673-","A4674-","C4675-","T4676-","A4677-","T4678-","A4679-","A4680-","A4681-","C4682-","T4683-","A4684-","A4685-","C4686-","T4687-","T4688-","A4689-","T4690-","G4691-","A4692-","C4693-","T4694-","T4695-","A4696-","A4697-","C4698-","T4699-","A4700-","A4701-","C4702-","T4703-","T4704-","A4705-","T4706-","G4707-","A4708-","C4709-","T4710-","T4711-","A4712-","A4713-","C4714-","T4715-","A4716-","A4717-","C4718-","T4719-","T4720-","A4721-","T4722-","G4723-","A4724-","C4725-","T4726-","T4727-","A4728-","A4729-","C4730-","T4731-","A4732-","A4733-","C4734-","T4735-","T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","A4748-","A4749-","C4750-","T4751-","T4752-","A4753-","T4754-","G4755-","A4756-","C4757-","T4758-","T4759-","A4760-","A4761-","C4762-","T4763-","A4764-","A4765-","C4766-","T4767-","T4768-","A4769-","T4770-","G4771-","A4772-","C4773-","T4774-","T4775-","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","A4807-","T4808-","T4809-","A4810-","A4811-","C4812-","T4813-","C4814-","A4815-","T4816-","T4817-","T4818-","C4819-","A4820-","A4821-","G4822-","A4823-","A4824-","A4825-","G4826-","G4827-","T4828-","G4829-","G4830-","G4831-","T4832-","G4833-","G4834-","A4835-","T4836-","A4837-","G4838-","A4839-","A4840-","C4841-","T4842-","C4843-","T4844-","A4845-","T4846-","A4847-","T4848-","G4849-","A4850-","C4851-","A4852-","G4853-","C4854-","T4855-","T4856-","G4857-","T4858-","G4859-","A4860-","A4861-","A4862-","C4863-","A4864-","A4865-","T4866-","T4867-","A4868-","G4869-","A4870-","T4871-","C4872-","C4873-","C4874-","T4875-","A4876-","A4877-","T4878-","T4879-","T4880-","C4881-","T4882-","A4883-","A4884-","T4885-","G4886-","G4887-","A4888-","A4889-","G4890-","T4891-","T4892-","T4893-","T4894-","G4895-","A4896-","T4897-","A4898-","G4899-","G4900-","A4901-","G4902-","A4903-","T4904-","T4905-","G4906-","T4907-","C4908-","A4909-","T4910-","C4911-","A4912-","G4913-","T4914-","T4915-","G4916-","A4917-","T4918-","A4919-","C4920-","A4921-","T4922-","T4923-","G4924-","T4925-","T4926-","T4927-","A4928-","T4929-","T4930-","A4931-","T4932-","C4933-","T4934-","C4935-","A4936-","T4937-","C4938-","T4939-","A4940-","T4941-","T4942-","A4943-","G4944-","A4945-","G4946-","C4947-","A4948-","C4949-","G4950-","T4951-","C4952-","T4953-","G4954-","T4955-","T4956-","T4957-","A4958-","G4959-","A4960-","G4961-","C4962-","T4963-","T4964-","T4965-","A4966-","G4967-","T4968-","G4969-","A4970-","C4971-","C4972-","T4973-","G4974-","C4975-","T4976-","C4977-","G4978-","G4979-","T4980-","T4981-","A4982-","C4983-","T4984-","T4985-","C4986-","T4987-","G4988-","T4989-","G4990-","T4991-","A4992-","A4993-","A4994-","T4995-","C4996-","T4997-","T4998-","G4999-","A5000-","A5001-","T5002-","C5003-","C5004-","T5005-","T5006-","T5007-","A5008-","G5009-","T5010-","G5011-","A5012-","T5013-","A5014-","C5015-","A5016-","C5017-","T5018-","G5019-","T5020-","G5021-","T5022-","C5023-","A5024-","A5025-","A5026-","A5027-","C5028-","T5029-","G5030-","G5031-","A5032-","T5033-","G5034-","T5035-","T5036-","T5037-","A5038-","G5039-","A5040-","A5041-","T5042-","A5043-","C5044-","C5045-","T5046-","A5047-","T5048-","G5049-","T5050-","A5051-","G5052-","A5053-","A5054-","T5055-","A5056-","T5057-","G5058-","G5059-","G5060-","A5061-","A5062-","G5063-","C5064-","A5065-","T5066-","G5067-","C5068-","T5069-","T5070-","G5071-","T5072-","T5073-","T5074-","T5075-","T5076-","G5077-","T5078-","C5079-","T5080-","C5081-","T5082-","A5083-","T5084-","T5085-","A5086-","T5087-","A5088-","G5089-","A5090-","T5091-","T5092-","A5093-","A5094-","C5095-","T5096-","C5097-","A5098-","T5099-","A5100-","C5101-","A5102-","T5103-","G5104-","G5105-","T5106-","T5107-","G5108-","T5109-","A5110-","T5111-","T5112-","A5113-","T5114-","G5115-","A5116-","A5117-","T5118-","T5119-","T5120-","T5121-","C5122-","A5123-","T5124-","C5125-","T5126-","G5127-","C5128-","C5129-","T5130-","A5131-","A5132-","T5133-","G5134-","T5135-","A5136-","C5137-","T5138-","C5139-","C5140-","A5141-","A5142-","T5143-","T5144-","C5145-","T5146-","T5147-","G5148-","T5149-","T5150-","T5151-","A5152-","C5153-","A5154-","A5155-","T5156-","C5157-","A5158-","A5159-","T5160-","T5161-","A5162-","T5163-","A5164-","T5165-","A5166-","A5167-","T5168-","C5169-","A5170-","A5171-","A5172-","G5173-","A5174-","G5175-","T5176-","G5177-","A5178-","T5179-","G5180-","A5181-","T5182-","G5183-","C5184-","A5185-","T5186-","A5187-","C5188-","A5189-","C5190-","A5191-","T5192-","T5193-","A5194-","C5195-","A5196-","A5197-","A5198-","G5199-","T5200-","G5201-","A5202-","A5203-","T5204-","A5205-","A5206-","T5207-","C5208-","T5209-","A5210-","C5211-","C5212-","A5213-","T5214-","C5215-","A5216-","T5217-","A5218-","A5219-","A5220-","A5221-","T5222-","A5223-","C5224-","T5225-","T5226-","G5227-","A5228-","T5229-","A5230-","C5231-","A5232-","G5233-","A5234-","G5235-","C5236-","T5237-","T5238-","T5239-","A5240-","T5241-","C5242-","A5243-","C5244-","A5245-","T5246-","C5247-","A5248-","T5249-","G5250-","G5251-","T5252-","T5253-","T5254-","T5255-","C5256-","A5257-","A5258-","T5259-","T5260-","G5261-","T5262-","A5263-","T5264-","T5265-","A5266-","T5267-","T5268-","A5269-","A5270-","G5271-","T5272-","A5273-","T5274-","A5275-","G5276-","C5277-","T5278-","A5279-","A5280-","T5281-","T5282-","T5283-","T5284-","A5285-","T5286-","A5287-","C5288-","A5289-","G5290-","T5291-","C5292-","A5293-","A5294-","T5295-","A5296-","G5297-","A5298-","C5299-","A5300-","A5301-","T5302-","G5303-","G5304-","T5305-","T5306-","C5307-","T5308-","C5309-","T5310-","A5311-","A5312-","G5313-","C5314-","A5315-","A5316-","T5317-","A5318-","T5319-","T5320-","T5321-","C5322-","T5323-","A5324-","A5325-","T5326-","A5327-","T5328-","T5329-","T5330-","T5331-","A5332-","A5333-","G5334-","A5335-","T5336-","G5337-","T5338-","G5339-","C5340-","T5341-","T5342-","C5343-","C5344-","C5345-","T5346-","A5347-","C5348-","G5349-","G5350-","G5351-","C5352-","G5353-","A5354-","T5355-","G5356-","A5357-","C5358-","A5359-","G5360-","A5361-","T5362-","C5363-","C5364-","C5365-","C5366-","T5367-","A5368-","T5369-","C5370-","C5371-","A5372-","C5373-","G5374-","G5375-","C5376-","C5377-","A5378-","C5379-","G5380-","T5381-","C5382-","A5383-","A5384-","G5385-","A5386-","C5387-","A5388-","T5389-","G5390-","T5391-","A5392-","T5393-","A5394-","T5395-","C5396-","C5397-","A5398-","T5399-","T5400-","A5401-","C5402-","T5403-","C5404-","A5405-","T5406-","T5407-","A5408-","C5409-","T5410-","G5411-","C5412-","G5413-","T5414-","T5415-","G5416-","A5417-","C5418-","A5419-","T5420-","T5421-","T5422-","G5423-","C5424-","T5425-","C5426-","C5427-","A5428-","T5429-","T5430-","T5431-","T5432-","C5433-","T5434-","A5435-","A5436-","T5437-","A5438-","G5439-","C5440-","C5441-","A5442-","T5443-","G5444-","A5445-","T5446-","A5447-","C5448-","T5449-","A5450-","A5451-","A5452-","T5453-","C5454-","T5455-","A5456-","T5457-","A5458-","T5459-","A5460-","A5461-","C5462-","C5463-","T5464-","G5465-","C5466-","A5467-","T5468-","A5469-","G5470-","A5471-","T5472-","A5473-","G5474-","C5475-","G5476-","C5477-","G5478-","A5479-","T5480-","A5481-","A5482-","A5483-","G5484-","C5485-","A5486-","A5487-","G5488-","G5489-","T5490-","C5491-","C5492-","T5493-","T5494-","C5495-","C5496-","A5497-","C5498-","C5499-","A5500-","G5501-","C5502-","A5503-","T5504-","C5505-","T5506-","A5507-","G5508-","T5509-","T5510-","G5511-","A5512-","T5513-","T5514-","G5515-","A5516-","T5517-","A5518-","T5519-","C5520-","T5521-","T5522-","C5523-","A5524-","A5525-","T5526-","A5527-","T5528-","A5529-","T5530-","G5531-","G5532-","G5533-","A5534-","T5535-","A5536-","C5537-","A5538-","A5539-","A5540-","G5541-","C5542-","T5543-","T5544-","A5545-","T5546-","A5547-","A5548-","A5549-","T5550-","T5551-","T5552-","C5553-","T5554-","A5555-","A5556-","T5557-","A5558-","C5559-","T5560-","G5561-","T5562-","G5563-","G5564-","G5565-","T5566-","T5567-","C5568-","A5569-","T5570-","C5571-","T5572-","A5573-","C5574-","A5575-","A5576-","G5577-","G5578-","A5579-","A5580-","T5581-","C5582-","C5583-","C5584-","C5585-","T5586-","A5587-","G5588-","T5589-","A5590-","T5591-","A5592-","C5593-","T5594-","G5595-","A5596-","A5597-","T5598-","T5599-","A5600-","T5601-","T5602-","T5603-","T5604-","A5605-","T5606-","A5607-","T5608-","A5609-","G5610-","A5611-","T5612-","C5613-","T5614-","A5615-","A5616-","T5617-","T5618-","T5619-","A5620-","A5621-","C5622-","A5623-","T5624-","C5625-","A5626-","T5627-","T5628-","T5629-","T5630-","C5631-","A5632-","T5633-","C5634-","T5635-","G5636-","G5637-","G5638-","A5639-","T5640-","A5641-","C5642-","C5643-","A5644-","C5645-","A5646-","A5647-","T5648-","T5649-","C5650-","A5651-","A5652-","A5653-","A5654-","T5655-","A5656-","A5657-","A5658-","C5659-","T5660-","C5661-","A5662-","A5663-","C5664-","A5665-","A5666-","C5667-","A5668-","C5669-","T5670-","A5671-","C5672-","T5673-","T5674-","T5675-","C5676-","C5677-","T5678-","T5679-","T5680-","T5681-","T5682-","A5683-","C5684-","A5685-","T5686-","A5687-","T5688-","T5689-","C5690-","C5691-","C5692-","C5693-","T5694-","A5695-","A5696-","A5697-","A5698-","T5699-","A5700-","G5701-","G5702-","C5703-","A5704-","T5705-","T5706-","C5707-","A5708-","A5709-","G5710-","C5711-","A5712-","T5713-","T5714-","C5715-","T5716-","A5717-","T5718-","T5719-","T5720-","T5721-","A5722-","T5723-","A5724-","T5725-","A5726-","T5727-","T5728-","A5729-","C5730-","A5731-","G5732-","C5733-","C5734-","C5735-","C5736-","A5737-","T5738-","G5739-","A5740-","T5741-","C5742-","T5743-","A5744-","C5745-","C5746-","A5747-","T5748-","A5749-","A5750-","G5751-","A5752-","T5753-","C5754-","A5755-","A5756-","C5757-","A5758-","A5759-","T5760-","G5761-","T5762-","C5763-","T5764-","A5765-","T5766-","T5767-","T5768-","C5769-","T5770-","A5771-","C5772-","A5773-","T5774-","A5775-","T5776-","G5777-","C5778-","A5779-","T5780-","T5781-","A5782-","G5783-","A5784-","T5785-","A5786-","G5787-","A5788-","T5789-","A5790-","G5791-","T5792-","A5793-","A5794-","A5795-","G5796-","T5797-","A5798-","A5799-","G5800-","A5801-","G5802-","A5803-","T5804-","C5805-","T5806-","T5807-","G5808-","C5809-","A5810-","C5811-","A5812-","G5813-","A5814-","A5815-","T5816-","T5817-","A5818-","C5819-","A5820-","A5821-","T5822-","T5823-","C5824-","T5825-","T5826-","A5827-","A5828-","T5829-","A5830-","A5831-","T5832-","T5833-","A5834-","T5835-","A5836-","G5837-","A5838-","G5839-","A5840-","A5841-","A5842-","A5843-","T5844-","A5845-","T5846-","C5847-","T5848-","T5849-","C5850-","C5851-","A5852-","T5853-","A5854-","T5855-","A5856-","A5857-","T5858-","T5859-","C5860-","T5861-","T5862-","T5863-","G5864-","A5865-","C5866-","A5867-","C5868-","T5869-","A5870-","A5871-","T5872-","G5873-","C5874-","A5875-","G5876-","A5877-","T5878-","A5879-","T5880-","A5881-","A5882-","T5883-","A5884-","T5885-","C5886-","T5887-","T5888-","T5889-","A5890-","T5891-","A5892-","T5893-","G5894-","T5895-","A5896-","A5897-","T5898-","A5899-","T5900-","A5901-","T5902-","G5903-","C5904-","A5905-","A5906-","A5907-","C5908-","A5909-","G5910-","T5911-","C5912-","T5913-","A5914-","T5915-","C5916-","T5917-","A5918-","C5919-","T5920-","A5921-","T5922-","A5923-","T5924-","A5925-","C5926-","T5927-","G5928-","A5929-","T5930-","C5931-","A5932-","A5933-","T5934-","A5935-","T5936-","T5937-","A5938-","T5939-","C5940-","T5941-","C5942-","T5943-","A5944-","T5945-","G5946-","A5947-","A5948-","T5949-","C5950-","C5951-","T5952-","A5953-","A5954-","A5955-","A5956-","T5957-","A5958-","A5959-","T5960-","C5961-","A5962-","T5963-","A5964-","C5965-","A5966-","G5967-","A5968-","A5969-","C5970-","A5971-","T5972-","C5973-","T5974-","A5975-","C5976-","A5977-","G5978-","G5979-","A5980-","T5981-","C5982-","A5983-","C5984-","A5985-","A5986-","A5987-","T5988-","T5989-","G5990-","G5991-","T5992-","T5993-","C5994-","A5995-","A5996-","G5997-","G5998-","A5999-","G6000-","A6001-","A6002-","A6003-","T6004-","C6005-","T6006-","A6007-","T6008-","C6009-","A6010-","A6011-","A6012-","T6013-","A6014-","T6015-","T6016-","T6017-","T6018-","C6019-","C6020-","T6021-","G6022-","T6023-","C6024-","A6025-","A6026-","C6027-","A6028-","A6029-","C6030-","T6031-","G6032-","G6033-","T6034-","T6035-","C6036-","T6037-","A6038-","G6039-","A6040-","A6041-","C6042-","A6043-","T6044-","A6045-","A6046-","C6047-","A6048-","G6049-","T6050-","C6051-","A6052-","A6053-","C6054-","A6055-","C6056-","C6057-","T6058-","A6059-","A6060-","T6061-","C6062-","C6063-","A6064-","T6065-","G6066-","T6067-","T6068-","T6069-","T6070-","T6071-","T6072-","A6073-","T6074-","A6075-","A6076-","T6077-","C6078-","A6079-","T6080-","C6081-","T6082-","A6083-","C6084-","C6085-","A6086-","A6087-","A6088-","G6089-","A6090-","T6091-","A6092-","A6093-","T6094-","G6095-","A6096-","C6097-","C6098-","A6099-","A6100-","A6101-","G6102-","A6103-","T6104-","C6105-","G6106-","A6107-","G6108-","G6109-","T6110-","C6111-","G6112-","T6113-","C6114-","G6115-","T6116-","G6117-","A6118-","A6119-","A6120-","C6121-","T6122-","G6123-","C6124-","T6125-","C6126-","A6127-","T6128-","C6129-","G6130-","A6131-","C6132-","A6133-","G6134-","C6135-","C6136-","A6137-","T6138-","G6139-","A6140-","A6141-","A6142-","T6143-","C6144-","T6145-","A6146-","C6147-","C6148-","G6149-","A6150-","C6151-","T6152-","C6153-","C6154-","A6155-","T6156-","G6157-","G6158-","T6159-","G6160-","C6161-","G6162-","A6163-","A6164-","T6165-","C6166-","G6167-","C6168-","A6169-","C6170-","T6171-","G6172-","T6173-","C6174-","T6175-","T6176-","A6177-","T6178-","T6179-","C6180-","G6181-","C6182-","C6183-","A6184-","T6185-","T6186-","G6187-","A6188-","T6189-","T6190-","T6191-","T6192-","C6193-","A6194-","T6195-","T6196-","T6197-","T6198-","T6199-","T6200-","A6201-","T6202-","A6203-","A6204-","T6205-","T6206-","A6207-","T6208-","G6209-","T6210-","A6211-","C6212-","A6213-","T6214-","G6215-","T6216-","T6217-","T6218-","T6219-","C6220-","C6221-","T6222-","T6223-","C6224-","T6225-","A6226-","T6227-","T6228-","C6229-","T6230-","C6231-","A6232-","A6233-","G6234-","A6235-","G6236-","T6237-","C6238-","T6239-","A6240-","C6241-","A6242-","A6243-","A6244-","A6245-","A6246-","T6247-","A6248-","T6249-","A6250-","T6251-","T6252-","T6253-","T6254-","T6255-","T6256-","C6257-","G6258-","A6259-","T6260-","A6261-","T6262-","C6263-","T6264-","A6265-","A6266-","G6267-","T6268-","A6269-","C6270-","T6271-","A6272-","A6273-","G6274-","T6275-","T6276-","T6277-","T6278-","T6279-","T6280-","T6281-","A6282-","C6283-","T6284-","G6285-","T6286-","T6287-","T6288-","T6289-","T6290-","G6291-","T6292-","T6293-","A6294-","C6295-","T6296-","G6297-","T6298-","C6299-","T6300-","T6301-","C6302-","C6303-","A6304-","T6305-","T6306-","C6307-","T6308-","T6309-","C6310-","T6311-","A6312-","A6313-","C6314-","T6315-","A6316-","A6317-","A6318-","G6319-","A6320-","T6321-","C6322-","T6323-","G6324-","A6325-","G6326-","A6327-","T6328-","A6329-","A6330-","A6331-","T6332-","T6333-","A6334-","T6335-","A6336-","C6337-","A6338-","A6339-","T6340-","C6341-","T6342-","T6343-","C6344-","G6345-","C6346-","T6347-","A6348-","T6349-","C6350-","G6351-","A6352-","A6353-","C6354-","C6355-","A6356-","T6357-","T6358-","T6359-","T6360-","T6361-","G6362-","T6363-","A6364-","G6365-","T6366-","C6367-","T6368-","A6369-","A6370-","A6371-","G6372-","C6373-","C6374-","T6375-","G6376-","A6377-","A6378-","G6379-","T6380-","A6381-","A6382-","T6383-","T6384-","A6385-","A6386-","C6387-","C6388-","A6389-","A6390-","C6391-","T6392-","G6393-","T6394-","T6395-","T6396-","T6397-","T6398-","A6399-","T6400-","T6401-","A6402-","G6403-","T6404-","G6405-","G6406-","C6407-","T6408-","T6409-","T6410-","T6411-","T6412-","T6413-","C6414-","G6415-","A6416-","T6417-","C6418-","T6419-","A6420-","T6421-","C6422-","C6423-","T6424-","C6425-","G6426-","T6427-","C6428-","C6429-","T6430-","C6431-","T6432-","C6433-","A6434-","T6435-","C6436-","A6437-","T6438-","C6439-","C6440-","T6441-","T6442-","A6443-","T6444-","A6445-","T6446-","T6447-","A6448-","T6449-","T6450-","A6451-","T6452-","C6453-","A6454-","T6455-","T6456-","A6457-","T6458-","T6459-","A6460-","T6461-","C6462-","A6463-","T6464-","A6465-","G6466-","T6467-","C6468-","T6469-","A6470-","T6471-","T6472-","A6473-","A6474-","A6475-","C6476-","A6477-","C6478-","A6479-","A6480-","A6481-","T6482-","C6483-","A6484-","T6485-","C6486-","T6487-","A6488-","C6489-","G6490-","T6491-","T6492-","T6493-","A6494-","T6495-","A6496-","A6497-","C6498-","A6499-","A6500-","C6501-","A6502-","T6503-","T6504-","C6505-","T6506-","C6507-","A6508-","T6509-","T6510-","A6511-","T6512-","T6513-","A6514-","A6515-","T6516-","T6517-","A6518-","G6519-","T6520-","T6521-","C6522-","T6523-","G6524-","T6525-","A6526-","G6527-","A6528-","A6529-","T6530-","A6531-","T6532-","C6533-","T6534-","T6535-","T6536-","A6537-","A6538-","T6539-","A6540-","A6541-","T6542-","T6543-","T6544-","G6545-","G6546-","C6547-","T6548-","A6549-","T6550-","A6551-","C6552-","A6553-","T6554-","C6555-","T6556-","G6557-","T6558-","T6559-","C6560-","A6561-","A6562-","T6563-","A6564-","C6565-","T6566-","A6567-","T6568-","C6569-","T6570-","A6571-","T6572-","T6573-","G6574-","A6575-","T6576-","G6577-","A6578-","T6579-","T6580-","T6581-","C6582-","T6583-","T6584-","T6585-","T6586-","T6587-","T6588-","A6589-","A6590-","G6591-","A6592-","C6593-","T6594-","T6595-","A6596-","A6597-","A6598-","C6599-","T6600-","A6601-","G6602-","T6603-","T6604-","A6605-","T6606-","G6607-","G6608-","T6609-","A6610-","A6611-","T6612-","G6613-","A6614-","C6615-","G6616-","A6617-","T6618-","G6619-","A6620-","A6621-","A6622-","T6623-","C6624-","G6625-","A6626-","G6627-","T6628-","A6629-","G6630-","T6631-","A6632-","A6633-","C6634-","T6635-","T6636-","C6637-","T6638-","A6639-","A6640-","T6641-","A6642-","A6643-","A6644-","G6645-","A6646-","C6647-","T6648-","T6649-","G6650-","A6651-","T6652-","A6653-","T6654-","C6655-","A6656-","T6657-","T6658-","A6659-","T6660-","C6661-","A6662-","T6663-","A6664-","T6665-","G6666-","T6667-","T6668-","T6669-","G6670-","A6671-","T6672-","C6673-","G6674-","T6675-","C6676-","A6677-","T6678-","A6679-","G6680-","T6681-","T6682-","A6683-","A6684-","T6685-","A6686-","G6687-","T6688-","G6689-","T6690-","G6691-","G6692-","C6693-","T6694-","A6695-","A6696-","A6697-","T6698-","G6699-","G6700-","T6701-","A6702-","C6703-","T6704-","G6705-","T6706-","T6707-","A6708-","A6709-","T6710-","A6711-","A6712-","G6713-","T6714-","T6715-","T6716-","A6717-","T6718-","A6719-","G6720-","A6721-","C6722-","A6723-","A6724-","T6725-","A6726-","T6727-","C6728-","A6729-","T6730-","A6731-","G6732-","T6733-","A6734-","T6735-","T6736-","T6737-","T6738-","C6739-","T6740-","T6741-","T6742-","C6743-","C6744-","A6745-","G6746-","A6747-","A6748-","T6749-","T6750-","A6751-","G6752-","A6753-","T6754-","T6755-","A6756-","T6757-","T6758-","T6759-","T6760-","T6761-","T6762-","T6763-","A6764-","A6765-","A6766-","T6767-","A6768-","C6769-","T6770-","G6771-","A6772-","T6773-","C6774-","C6775-","T6776-","C6777-","A6778-","C6779-","A6780-","A6781-","T6782-","T6783-","C6784-","C6785-","G6786-","T6787-","G6788-","A6789-","T6790-","G6791-","T6792-","A6793-","G6794-","C6795-","A6796-","G6797-","T6798-","A6799-","G6800-","T6801-","T6802-","G6803-","G6804-","T6805-","G6806-","C6807-","A6808-","T6809-","G6810-","G6811-","T6812-","C6813-","T6814-","A6815-","T6816-","A6817-","T6818-","C6819-","G6820-","T6821-","T6822-","A6823-","A6824-","A6825-","A6826-","T6827-","G6828-","T6829-","A6830-","T6831-","C6832-","A6833-","T6834-","A6835-","T6836-","A6837-","T6838-","A6839-","A6840-","T6841-","A6842-","G6843-","T6844-","T6845-","T6846-","T6847-","C6848-","T6849-","G6850-","A6851-","C6852-","G6853-","T6854-","G6855-","G6856-","A6857-","G6858-","T6859-","A6860-","C6861-","A6862-","G6863-","A6864-","A6865-","T6866-","T6867-","T6868-","T6869-","C6870-","G6871-","A6872-","T6873-","T6874-","A6875-","A6876-","T6877-","G6878-","A6879-","G6880-","T6881-","T6882-","C6883-","A6884-","T6885-","G6886-","G6887-","T6888-","A6889-","A6890-","G6891-","G6892-","A6893-","A6894-","G6895-","G6896-","G6897-","C6898-","A6899-","A6900-","A6901-","T6902-","G6903-","C6904-","C6905-","T6906-","G6907-","T6908-","A6909-","T6910-","A6911-","T6912-","A6913-","A6914-","T6915-","A6916-","T6917-","A6918-","C6919-","A6920-","T6921-","A6922-","A6923-","G6924-","T6925-","T6926-","A6927-","A6928-","T6929-","A6930-","G6931-","T6932-","T6933-","T6934-","T6935-","T6936-","T6937-","A6938-","T6939-","C6940-","A6941-","T6942-","A6943-","T6944-","T6945-","T6946-","T6947-","C6948-","T6949-","A6950-","A6951-","T6952-","A6953-","C6954-","C6955-","A6956-","T6957-","A6958-","A6959-","T6960-","A6961-","A6962-","A6963-","A6964-","A6965-","T6966-","T6967-","A6968-","T6969-","C6970-","A6971-","T6972-","T6973-","A6974-","T6975-","G6976-","C6977-","G6978-","T6979-","T6980-","T6981-","G6982-","G6984-","T6985-","A6986-","G6987-","T6988-","T6989-","C6990-","T6991-","G6992-","C6993-","C6994-","C6995-","T6996-","A6997-","T6998-","C6999-","A7000-","T7001-","C7002-","T7003-","A7004-","T7005-","A7006-","T7007-","C7008-","A7009-","C7010-","T7011-","G7012-","T7013-","C7014-","A7015-","C7016-","T7017-","C7018-","T7019-","C7020-","G7021-","C7022-","T7023-","C7024-","T7025-","C7026-","A7027-","C7028-","T7029-","A7030-","T7031-","A7032-","T7033-","C7034-","T7035-","T7036-","C7037-","T7038-","A7039-","A7040-","A7041-","A7042-","T7043-","T7044-","A7045-","C7046-","A7047-","A7048-","A7049-","C7050-","A7051-","A7052-","C7053-","T7054-","G7055-","G7056-","A7057-","T7058-","A7059-","T7060-","T7061-","C7062-","G7063-","A7064-","T7065-","A7066-","A7067-","C7068-","A7069-","G7070-","C7071-","A7072-","T7073-","T7074-","T7075-","G7076-","T7077-","G7078-","T7079-","A7080-","G7081-","T7082-","T7083-","T7084-","T7085-","T7086-","G7087-","T7088-","C7089-","T7090-","T7091-","T7092-","T7093-","A7094-","C7095-","A7096-","G7097-","T7098-","A7099-","T7100-","A7101-","T7102-","A7103-","C7104-","G7105-","T7106-","T7107-","A7108-","T7109-","T7110-","G7111-","T7112-","C7113-","A7114-","A7115-","A7116-","A7117-","T7118-","C7119-","T7120-","A7121-","A7122-","A7123-","C7124-","A7125-","A7126-","A7127-","T7128-","A7129-","T7130-","T7131-","A7132-","G7133-","C7134-","A7135-","T7136-","A7137-","A7138-","T7139-","A7140-","C7141-","A7142-","T7143-","C7144-","T7145-","A7146-","T7147-","C7148-","T7149-","A7150-","T7151-","A7152-","A7153-","G7154-","A7155-","T7156-","C7157-","A7158-","G7159-","G7160-","A7161-","T7162-","C7163-","C7164-","A7165-","T7166-","G7167-","T7168-","T7169-","C7170-","G7171-","A7172-","G7173-","C7174-","A7175-","T7176-","A7177-","C7178-","T7179-","A7180-","G7181-","C7182-","C7183-","A7184-","T7185-","G7186-","T7187-","A7188-","T7189-","A7190-","T7191-","T7192-","T7193-","G7194-","T7195-","A7196-","A7197-","C7198-","T7199-","T7200-","C7201-","G7202-","T7203-","C7204-","G7205-","T7206-","A7207-","C7208-","A7209-","G7210-","C7211-","G7212-","T7213-","T7214-","A7215-","G7216-","A7217-","T7218-","C7219-","A7220-","A7221-","T7222-","A7223-","G7224-","A7225-","A7226-","T7227-","A7228-","A7229-","A7230-","C7231-","A7232-","A7233-","T7234-","C7235-","G7236-","T7237-","G7238-","T7239-","G7240-","A7241-","C7242-","G7243-","C7244-","A7245-","A7246-","C7247-","T7248-","T7249-","T7250-","T7251-","T7252-","T7253-","A7254-","C7255-","G7256-","A7257-","T7258-","C7259-","T7260-","A7261-","G7262-","T7263-","T7264-","G7265-","T7266-","A7267-","T7268-","G7269-","A7270-","G7271-","T7272-","T7273-","T7274-","A7275-","T7276-","C7277-","G7278-","T7279-","T7280-","T7281-","A7282-","C7283-","A7284-","T7285-","A7286-","A7287-","G7288-","C7289-","A7290-","A7291-","T7292-","T7293-","A7294-","A7295-","C7296-","G7297-","G7298-","C7299-","T7300-","T7301-","T7302-","A7303-","A7304-","C7305-","A7306-","G7307-","A7308-","T7309-","G7310-","A7311-","T7312-","C7313-","T7314-","G7315-","A7316-","G7317-","T7318-","A7319-","A7320-","T7321-","A7322-","A7323-","T7324-","A7325-","T7326-","A7327-","C7328-","C7329-","T7330-","C7331-","T7332-","G7333-","T7334-","T7335-","A7336-","T7337-","A7338-","C7339-","G7340-","T7341-","T7342-","T7343-","A7344-","A7345-","T7346-","G7347-","T7348-","T7349-","C7350-","A7351-","C7352-","G7353-","G7354-","T7355-","C7356-","T7357-","T7358-","A7359-","G7360-","T7361-","A7362-","T7363-","T7364-","T7365-","T7366-","T7367-","A7368-","G7369-","A7370-","T7371-","A7372-","T7373-","C7374-","A7375-","A7376-","T7377-","T7378-","G7379-","T7380-","G7381-","A7382-","T7383-","T7384-","T7385-","A7386-","C7387-","A7388-","C7389-","C7390-","A7391-","T7392-","A7393-","T7394-","T7395-","C7396-","G7397-","A7398-","C7399-","T7400-","C7401-","C7402-","C7403-","T7404-","T7405-","G7406-","T7407-","G7408-","T7409-","G7410-","T7411-","A7412-","A7413-","C7414-","G7415-","T7416-","T7417-","A7418-","G7419-","A7420-","A7421-","A7422-","T7423-","T7424-","C7425-","T7426-","A7427-","A7428-","A7429-","T7430-","C7431-","T7432-","A7433-","T7434-","A7435-","T7436-","T7437-","A7438-","T7439-","C7440-","T7441-","A7442-","T7443-","T7444-","A7445-","C7446-","A7447-","G7448-","C7449-","G7450-","T7451-","A7452-","A7453-","A7454-","A7455-","C7456-","A7457-","C7458-","A7459-","T7460-","T7461-","C7462-","A7463-","A7464-","T7465-","A7466-","T7467-","T7468-","G7469-","T7470-","A7471-","T7472-","T7473-","G7474-","T7475-","T7476-","A7477-","T7478-","T7479-","T7480-","T7481-","T7482-","A7483-","T7484-","A7485-","T7486-","T7487-","A7488-","T7489-","T7490-","T7491-","A7492-","C7493-","A7494-","C7495-","A7496-","A7497-","T7498-","T7499-","A7500-","A7501-","C7502-","A7503-","A7504-","T7505-","G7506-","T7507-","A7508-","T7509-","T7510-","A7511-","T7512-","T7513-","A7514-","G7515-","T7516-","T7517-","T7518-","A7519-","T7520-","A7521-","T7522-","T7523-","A7524-","C7525-","T7526-","G7527-","A7528-","A7529-","T7530-","T7531-","A7532-","A7533-","T7534-","A7535-","A7536-","T7537-","A7538-","T7539-","A7540-","A7541-","A7542-","A7543-","T7544-","T7545-","C7546-","C7547-","C7548-","A7549-","A7550-","T7551-","C7552-","T7553-","T7554-","G7555-","T7556-","C7557-","A7558-","T7559-","A7560-","A7561-","A7562-","C7563-","A7564-","C7565-","A7566-","A7567-","A7568-","A7569-","T7570-","C7571-","C7572-","A7573-","T7574-","T7575-","A7576-","A7577-","A7578-","A7579-","A7580-","T7581-","G7582-","T7583-","C7584-","G7585-","A7586-","T7587-","A7588-","A7589-","A7590-","A7591-","T7592-","A7593-","T7594-","C7595-","T7596-","G7597-","A7598-","T7599-","G7600-","T7601-","T7602-","G7603-","T7604-","T7605-","G7606-","T7607-","T7608-","C7609-","G7610-","C7611-","T7612-","G7613-","C7614-","T7615-","A7616-","T7617-","G7618-","A7619-","T7620-","A7621-","A7622-","T7623-","C7624-","A7625-","G7626-","A7627-","T7628-","C7629-","A7630-","T7631-","T7632-","A7633-","G7634-","C7635-","C7636-","G7637-","A7638-","T7639-","A7640-","G7641-","T7642-","G7643-","G7644-","T7645-","A7646-","A7647-","T7648-","G7649-","C7650-","T7651-","A7652-","T7653-","C7654-","G7655-","A7656-","A7657-","A7658-","C7659-","A7660-","A7661-","C7662-","A7663-","T7664-","C7665-","G7666-","C7667-","C7668-","A7669-","G7670-","A7671-","A7672-","A7673-","T7674-","T7675-","A7676-","C7677-","A7678-","A7679-","A7680-","C7681-","G7682-","C7683-","T7684-","A7685-","C7686-","A7687-","A7688-","C7689-","A7690-","G7691-","A7692-","T7693-","A7694-","T7695-","T7696-","C7697-","C7698-","A7699-","G7700-","C7701-","T7702-","A7703-","T7704-","C7705-","A7706-","G7707-","A7708-","T7709-","T7710-","A7711-","T7712-","G7713-","T7714-","G7715-","G7716-","T7717-","C7718-","C7719-","A7720-","G7721-","A7722-","G7723-","G7724-","G7725-","A7726-","G7727-","A7728-","T7729-","G7730-","G7731-","A7732-","T7733-","A7734-","T7735-","T7736-","G7737-","T7738-","T7739-","T7740-","A7741-","C7742-","A7743-","C7744-","G7745-","G7746-","T7747-","G7748-","A7749-","C7750-","T7751-","G7752-","T7753-","A7754-","T7755-","C7756-","C7757-","A7758-","C7759-","G7760-","C7761-","T7762-","A7763-","G7764-","A7765-","G7766-","A7767-","T7768-","A7769-","T7770-","C7771-","G7772-","A7773-","C7774-","G7775-","G7776-","T7777-","A7778-","T7779-","G7780-","T7781-","A7782-","T7783-","T7784-","G7785-","T7786-","A7787-","G7788-","A7789-","T7790-","G7791-","C7792-","T7793-","C7794-","T7795-","C7796-","A7797-","T7798-","G7799-","G7800-","T7801-","T7802-","A7803-","T7804-","A7805-","C7806-","A7807-","G7808-","G7809-","T7810-","A7811-","T7812-","T7813-","A7814-","G7815-","A7816-","T7817-","G7818-","T7819-","C7820-","A7821-","G7822-","C7823-","A7824-","T7825-","G7826-","T7827-","A7828-","G7829-","T7830-","A7831-","T7832-","T7833-","A7834-","G7835-","T7836-","A7837-","G7838-","A7839-","C7840-","T7841-","A7842-","T7843-","C7844-","A7845-","A7846-","C7847-","G7848-","T7849-","T7850-","C7851-","A7852-","G7853-","G7854-","A7855-","A7856-","A7857-","A7858-","C7859-","C7860-","A7861-","G7862-","A7863-","C7864-","A7865-","C7866-","T7867-","A7868-","C7869-","A7870-","A7871-","C7872-","A7873-","T7874-","C7875-","A7876-","T7877-","A7878-","T7879-","A7880-","T7881-","C7882-","C7883-","C7884-","A7885-","T7886-","C7887-","T7888-","C7889-","T7890-","A7891-","G7892-","G7893-","T7894-","A7895-","T7896-","T7897-","G7898-","T7899-","G7900-","C7901-","T7902-","T7903-","G7904-","T7905-","A7906-","T7907-","T7908-","A7909-","G7910-","T7911-","A7912-","G7913-","G7914-","C7915-","A7916-","T7917-","T7918-","A7919-","T7920-","T7921-","A7922-","T7923-","T7924-","A7925-","C7926-","G7927-","T7928-","G7929-","T7930-","T7931-","G7932-","T7933-","C7934-","T7935-","A7936-","T7937-","T7938-","A7939-","T7940-","C7941-","T7942-","G7943-","T7944-","T7945-","T7946-","A7947-","T7948-","A7949-","T7950-","G7951-","T7952-","T7953-","C7954-","A7955-","C7956-","T7957-","C7958-","G7959-","A7960-","A7961-","G7962-","A7963-","A7964-","C7965-","T7966-","A7967-","A7968-","A7969-","C7970-","T7971-","A7972-","C7973-","C7974-","T7975-","A7976-","T7977-","A7978-","C7979-","A7980-","A7981-","G7982-","A7983-","T7984-","A7985-","T7986-","G7987-","G7988-","T7989-","T7990-","G7991-","T7992-","G7993-","T7994-","T7995-","A7996-","T7997-","A7998-","T7999-","T8000-","T8001-","T8002-","T8003-","T8004-","A8005-","T8006-","A8007-","A8008-","A8009-","A8010-","T8011-","T8012-","T8013-","T8014-","T8015-","T8016-","T8017-","A8018-","T8019-","G8020-","A8021-","G8022-","T8023-","A8024-","T8025-","T8026-","T8027-","T8028-","T8029-","A8030-","C8031-","A8032-","A8033-","A8034-","A8035-","A8036-","T8037-","G8038-","T8039-","A8040-","T8041-","A8042-","T8043-","G8044-","T8045-","A8046-","T8047-","A8048-","A8049-","A8050-","A8051-","A8052-","A8053-","A8054-","A8055-","T8056-","A8057-","C8058-","T8059-","A8060-","A8061-","G8062-","T8063-","A8064-","T8065-","A8066-","C8067-","G8068-","A8069-","T8070-","G8071-","T8072-","A8073-","T8074-","C8075-","C8076-","T8077-","G8078-","T8079-","A8080-","T8081-","T8082-","A8083-","T8084-","T8085-","T8086-","G8087-","T8088-","A8089-","T8090-","T8091-","T8092-","A8093-","T8094-","C8095-","T8096-","A8097-","A8098-","A8099-","C8100-","A8101-","A8102-","T8103-","A8104-","C8105-","T8106-","T8107-","C8108-","T8109-","G8110-","C8111-","C8112-","T8113-","C8114-","T8115-","A8116-","G8117-","A8118-","T8119-","G8120-","G8121-","G8122-","A8123-","T8124-","A8125-","C8126-","A8127-","A8128-","A8129-","A8130-","A8131-","T8132-","T8133-","T8134-","T8135-","T8136-","T8137-","A8138-","T8139-","T8140-","T8141-","C8142-","A8143-","G8144-","C8145-","A8146-","T8147-","A8148-","T8149-","T8150-","A8151-","A8152-","A8153-","G8154-","T8155-","A8156-","A8157-","A8158-","A8159-","T8160-","C8161-","T8162-","A8163-","G8164-","T8165-","T8166-","A8167-","C8168-","C8169-","T8170-","T8171-","G8172-","A8173-","A8174-","A8175-","A8176-","T8177-","G8178-","A8179-","A8180-","T8181-","A8182-","C8183-","A8184-","G8185-","T8186-","G8187-","G8188-","G8189-","T8190-","G8191-","G8192-","T8193-","T8194-","C8195-","C8196-","G8197-","T8198-","A8199-","T8200-","C8201-","A8202-","C8203-","C8204-","A8205-","G8206-","T8207-","A8208-","A8209-","G8210-","A8211-","A8212-","C8213-","A8214-","T8215-","A8216-","A8217-","T8218-","A8219-","G8220-","T8221-","C8222-","G8223-","A8224-","A8225-","T8226-","A8227-","C8228-","A8229-","G8230-","T8231-","A8232-","T8233-","C8234-","C8235-","G8236-","A8237-","T8238-","T8239-","G8240-","A8241-","G8242-","A8243-","T8244-","T8245-","T8246-","T8247-","G8248-","C8249-","A8250-","T8251-","A8252-","C8253-","A8254-","A8255-","T8256-","A8257-","C8258-","T8259-","A8260-","G8261-","T8262-","C8263-","T8264-","A8265-","G8266-","A8267-","A8268-","A8269-","G8270-","A8271-","A8272-","A8273-","T8274-","T8275-","T8276-","G8277-","T8278-","A8279-","A8280-","T8281-","C8282-","A8283-","T8284-","C8285-","C8286-","T8287-","C8288-","T8289-","G8290-","T8291-","G8292-","A8293-","C8294-","A8295-","G8296-","G8297-","A8298-","G8299-","T8300-","C8301-","C8302-","A8303-","T8304-","A8305-","T8306-","A8307-","T8308-","C8309-","T8310-","G8311-","T8312-","A8313-","T8314-","C8315-","A8316-","T8317-","C8318-","G8319-","T8320-","C8321-","T8322-","A8323-","G8324-","T8325-","T8326-","T8327-","T8328-","T8329-","A8330-","T8331-","C8332-","A8333-","G8334-","T8335-","G8336-","T8337-","C8338-","C8339-","T8340-","A8341-","T8342-","G8343-","C8344-","T8345-","A8346-","T8347-","A8348-","T8349-","T8350-","C8351-","C8352-","T8353-","G8354-","T8355-","T8356-","A8357-","T8358-","C8359-","A8360-","T8361-","C8362-","A8363-","T8364-","T8365-","A8366-","G8367-","T8368-","T8369-","A8370-","A8371-","T8372-","G8373-","A8374-","A8375-","A8376-","A8377-","T8378-","A8379-","A8380-","C8381-","T8382-","C8383-","T8384-","C8385-","G8386-","T8387-","G8388-","C8389-","T8390-","T8391-","C8392-","A8393-","G8394-","A8395-","A8396-","A8397-","A8398-","G8399-","T8400-","C8401-","A8402-","A8403-","A8404-","T8405-","A8406-","T8407-","T8408-","G8409-","T8410-","A8411-","T8412-","C8413-","C8414-","A8415-","T8416-","A8417-","C8418-","A8419-","T8420-","A8421-","T8422-","A8423-","T8424-","C8425-","T8426-","C8427-","C8428-","A8429-","A8430-","A8431-","A8432-","C8433-","T8434-","A8435-","T8436-","C8437-","A8438-","C8439-","T8440-","T8441-","A8442-","T8443-","A8444-","C8445-","G8446-","T8447-","T8448-","T8449-","A8450-","T8451-","C8452-","T8453-","T8454-","T8455-","A8456-","A8457-","C8458-","G8459-","A8460-","A8461-","C8462-","A8463-","T8464-","A8465-","T8466-","A8467-","C8468-","C8469-","T8470-","A8471-","G8472-","A8473-","T8474-","G8475-","G8476-","T8477-","T8478-","A8479-","T8480-","T8481-","T8482-","A8483-","C8484-","T8485-","A8486-","A8487-","C8488-","A8489-","G8490-","A8491-","C8492-","A8493-","T8494-","T8495-","T8496-","T8497-","T8498-","T8499-","C8500-","A8501-","A8502-","G8503-","A8504-","T8505-","C8506-","T8507-","A8508-","T8509-","T8510-","G8511-","A8512-","C8513-","A8514-","A8515-","T8516-","A8517-","A8518-","C8519-","T8520-","C8521-","C8522-","T8523-","A8524-","T8525-","A8526-","G8527-","T8528-","T8529-","T8530-","C8531-","C8532-","A8533-","C8534-","A8535-","T8536-","C8537-","A8538-","A8539-","C8540-","C8541-","A8542-","A8543-","G8544-","T8545-","A8546-","A8547-","T8548-","G8549-","A8550-","T8551-","C8552-","A8553-","T8554-","C8555-","T8556-","A8557-","T8558-","T8559-","G8560-","T8561-","T8562-","A8563-","T8564-","A8565-","T8566-","A8567-","A8568-","C8569-","A8570-","A8571-","T8572-","A8573-","A8574-","C8575-","A8576-","T8577-","A8578-","A8579-","C8580-","T8581-","C8582-","T8583-","T8584-","T8585-","T8586-","C8587-","C8588-","A8589-","T8590-","T8591-","T8592-","T8593-","T8594-","A8595-","T8596-","C8597-","A8598-","G8599-","T8600-","A8601-","T8602-","C8603-","T8604-","A8605-","T8606-","A8607-","T8608-","C8609-","A8610-","A8611-","C8612-","G8613-","T8614-","C8615-","G8616-","T8617-","T8618-","G8619-","T8620-","A8621-","G8622-","T8623-","G8624-","A8625-","A8626-","T8627-","A8628-","G8629-","T8630-","A8631-","G8632-","T8633-","C8634-","A8635-","T8636-","T8637-","G8638-","A8639-","T8640-","C8641-","T8642-","A8643-","T8644-","T8645-","A8646-","T8647-","A8648-","T8649-","G8650-","A8651-","A8652-","A8653-","C8654-","G8655-","G8656-","A8657-","T8658-","A8659-","T8660-","G8661-","T8662-","C8663-","T8664-","A8665-","G8666-","T8667-","T8668-","A8669-","A8670-","T8671-","A8672-","T8673-","T8674-","T8675-","T8676-","C8677-","T8678-","T8679-","T8680-","G8681-","A8682-","T8683-","T8684-","T8685-","A8686-","A8687-","A8688-","G8689-","T8690-","C8691-","T8692-","A8693-","T8694-","A8695-","G8696-","T8697-","C8698-","T8699-","T8700-","T8701-","A8702-","C8703-","A8704-","A8705-","A8706-","C8707-","A8708-","T8709-","A8710-","A8711-","T8712-","A8713-","T8714-","C8715-","C8716-","T8717-","T8718-","A8719-","T8720-","C8721-","C8722-","G8723-","A8724-","C8725-","T8726-","T8727-","T8728-","A8729-","T8730-","A8731-","T8732-","T8733-","T8734-","C8735-","C8736-","T8737-","G8738-","T8739-","A8740-","G8741-","G8742-","G8743-","T8744-","G8745-","G8746-","C8747-","A8748-","T8749-","A8750-","A8751-","T8752-","T8753-","T8754-","T8755-","A8756-","T8757-","T8758-","C8759-","T8760-","G8761-","C8762-","C8763-","T8764-","C8765-","C8766-","A8767-","C8768-","A8769-","A8770-","T8771-","C8772-","A8773-","G8774-","T8775-","G8776-","T8777-","T8778-","T8779-","C8780-","C8781-","A8782-","A8783-","A8784-","T8785-","A8786-","T8787-","A8788-","T8789-","T8790-","A8791-","C8792-","T8793-","A8794-","G8795-","A8796-","C8797-","A8798-","A8799-","T8800-","A8801-","T8802-","T8803-","C8804-","C8805-","A8806-","T8807-","A8808-","T8809-","A8810-","G8811-","T8812-","T8813-","A8814-","T8815-","T8816-","A8817-","G8818-","T8819-","T8820-","A8821-","A8822-","G8823-","G8824-","G8825-","A8826-","C8827-","C8828-","C8829-","A8830-","A8831-","T8832-","T8833-","A8834-","G8835-","A8836-","A8837-","C8838-","A8839-","C8840-","G8841-","T8842-","A8843-","C8844-","G8845-","C8846-","G8847-","C8848-","T8849-","T8850-","A8851-","T8852-","T8853-","C8854-","A8855-","T8856-","C8857-","A8858-","T8859-","T8860-","T8861-","G8862-","G8863-","A8864-","T8865-","C8866-","G8867-","T8868-","A8869-","T8870-","T8871-","T8872-","C8873-","A8874-","T8875-","A8876-","A8877-","A8878-","A8879-","G8880-","T8881-","T8882-","A8883-","T8884-","T8885-","A8886-","T8887-","G8888-","T8889-","T8890-","A8891-","T8892-","A8893-","G8894-","A8895-","T8896-","G8897-","T8898-","C8899-","A8900-","A8901-","C8902-","A8903-","C8904-","A8905-","T8906-","T8907-","C8908-","T8909-","A8910-","C8911-","A8912-","T8913-","T8914-","T8915-","T8916-","T8917-","T8918-","T8919-","A8920-","A8921-","T8922-","T8923-","G8924-","T8925-","C8926-","T8927-","A8928-","T8929-","A8930-","T8931-","A8932-","G8933-","T8934-","A8935-","T8936-","T8937-","T8938-","T8939-","T8940-","C8941-","T8942-","G8943-","A8944-","T8945-","A8946-","T8947-","T8948-","T8949-","T8950-","C8951-","T8952-","A8953-","T8954-","A8955-","A8956-","T8957-","A8958-","T8959-","C8960-","A8961-","G8962-","A8963-","A8964-","T8965-","T8966-","G8967-","T8968-","C8969-","T8970-","T8971-","C8972-","C8973-","A8974-","T8975-","A8976-","G8977-","G8978-","A8979-","A8980-","G8981-","T8982-","T8983-","G8984-","T8985-","A8986-","T8987-","A8988-","C8989-","T8990-","A8991-","T8992-","T8993-","C8994-","G8995-","G8996-","A8997-","A8998-","T8999-","C9000-","A9001-","G9002-","T9003-","T9004-","A9005-","C9006-","A9007-","T9008-","G9009-","T9010-","T9011-","T9012-","A9013-","A9014-","A9015-","T9016-","A9017-","A9018-","T9019-","T9020-","C9021-","T9022-","C9023-","T9024-","G9025-","A9026-","T9027-","G9028-","T9029-","C9030-","A9031-","T9032-","T9033-","C9034-","C9035-","T9036-","T9037-","A9038-","T9039-","A9040-","C9041-","A9042-","A9043-","T9044-","C9045-","A9046-","A9047-","A9048-","T9049-","T9050-","C9051-","A9052-","T9053-","T9054-","A9055-","T9056-","T9057-","A9058-","A9059-","A9060-","C9061-","A9062-","G9063-","T9064-","T9065-","T9066-","A9067-","A9068-","T9069-","A9070-","G9071-","T9072-","C9073-","T9074-","G9075-","T9076-","A9077-","G9078-","A9079-","C9080-","C9081-","T9082-","T9083-","T9084-","A9085-","T9086-","C9087-","G9088-","T9089-","C9090-","G9091-","T9092-","A9093-","C9094-","A9095-","T9096-","A9097-","T9098-","C9099-","C9100-","A9101-","T9102-","T9103-","G9104-","T9105-","C9106-","T9107-","T9108-","A9109-","T9110-","T9111-","A9112-","G9113-","T9114-","T9115-","A9116-","C9117-","G9118-","C9119-","T9120-","T9121-","A9122-","T9123-","T9124-","T9125-","T9126-","T9127-","A9128-","T9129-","G9130-","G9131-","G9132-","T9133-","T9134-","T9135-","T9136-","A9137-","C9138-","G9139-","T9140-","T9141-","G9142-","C9143-","T9144-","T9145-","T9146-","A9147-","T9148-","T9149-","A9150-","T9151-","A9152-","T9153-","T9154-","T9155-","T9156-","A9157-","T9158-","A9159-","A9160-","T9161-","A9162-","A9163-","T9164-","G9165-","A9166-","T9167-","T9168-","G9169-","T9170-","T9171-","T9172-","G9173-","A9174-","C9175-","A9176-","A9177-","T9178-","G9179-","T9180-","C9181-","G9182-","T9183-","A9184-","G9185-","T9186-","A9187-","T9188-","A9189-","G9190-","A9191-","T9192-","A9193-","T9194-","A9195-","T9196-","T9197-","A9198-","T9199-","T9200-","A9201-","G9202-","A9203-","G9204-","G9205-","A9206-","G9207-","G9208-","T9209-","A9210-","T9211-","A9212-","A9213-","T9214-","T9215-","A9216-","T9217-","A9218-","A9219-","A9220-","A9221-","A9222-","G9223-","T9224-","T9225-","T9226-","C9227-","T9228-","G9229-","A9230-","G9231-","T9232-","A9233-","C9234-","G9235-","A9236-","T9237-","G9238-","T9239-","T9240-","A9241-","T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","C9257-","A9258-","T9259-","T9260-","A9261-","A9262-","C9263-","A9264-","T9265-","C9266-","A9267-","T9268-","A9269-","C9270-","A9271-","T9272-","C9273-","A9274-","A9275-","T9276-","T9277-","A9278-","A9279-","C9280-","T9281-","A9282-","C9283-","A9284-","T9285-","T9286-","C9287-","T9288-","T9289-","A9290-","T9291-","A9292-","A9293-","C9294-","A9295-","T9296-","T9297-","G9298-","T9299-","A9300-","A9301-","T9302-","C9303-","A9304-","A9305-","A9306-","A9307-","G9308-","A9309-","A9310-","T9311-","T9312-","G9313-","C9314-","A9315-","A9316-","T9317-","T9318-","T9319-","T9320-","G9321-","A9322-","T9323-","G9324-","T9325-","A9326-","T9327-","A9328-","A9329-","C9330-","A9331-","A9332-","C9333-","T9334-","G9335-","T9336-","C9337-","A9338-","A9339-","T9340-","G9341-","G9342-","A9343-","A9344-","T9345-","T9346-","G9347-","T9348-","A9349-","T9350-","A9351-","T9352-","T9353-","A9354-","C9355-","A9356-","A9357-","A9358-","T9359-","T9360-","A9361-","C9362-","G9363-","G9364-","T9365-","A9366-","T9367-","G9368-","T9369-","T9370-","G9371-","T9372-","A9373-","A9374-","C9375-","A9376-","A9377-","C9378-","A9379-","A9380-","A9381-","T9382-","A9383-","C9384-","C9385-","G9386-","A9387-","T9388-","C9389-","G9390-","G9391-","T9392-","A9393-","A9394-","T9395-","T9396-","G9397-","T9398-","C9399-","T9400-","C9401-","T9402-","G9403-","C9404-","C9405-","G9406-","C9407-","T9408-","G9409-","T9410-","A9411-","A9412-","T9413-","A9414-","G9415-","A9416-","A9417-","T9418-","T9419-","A9420-","A9421-","T9422-","T9423-","A9424-","T9425-","A9426-","T9427-","A9428-","T9429-","C9430-","T9431-","A9432-","T9433-","T9434-","A9435-","C9436-","A9437-","C9438-","C9439-","G9440-","G9441-","C9442-","C9443-","T9444-","T9445-","G9446-","T9447-","A9448-","T9449-","C9450-","A9451-","T9452-","A9453-","A9454-","T9455-","A9456-","A9457-","A9458-","G9459-","T9460-","T9461-","G9462-","T9463-","G9464-","G9465-","T9466-","A9467-","G9468-","T9469-","A9470-","T9471-","G9472-","A9473-","T9474-","C9475-","T9476-","C9477-","C9478-","A9479-","T9480-","A9481-","T9482-","T9483-","T9484-","A9485-","T9486-","A9487-","A9488-","T9489-","T9490-","T9491-","A9492-","G9493-","T9494-","A9495-","C9496-","T9497-","T9498-","T9499-","G9500-","T9501-","A9502-","T9503-","T9504-","T9505-","A9506-","G9507-","T9508-","T9509-","T9510-","T9511-","T9512-","T9513-","T9514-","G9515-","G9516-","A9517-","A9518-","T9519-","C9520-","A9521-","T9522-","A9523-","A9524-","A9525-","A9526-","A9527-","A9528-","A9529-","G9530-","T9531-","T9532-","T9533-","T9534-","A9535-","C9536-","T9537-","A9538-","A9539-","T9540-","T9541-","T9542-","A9543-","A9544-","A9545-","A9546-","T9547-","T9548-","T9549-","A9550-","A9551-","A9552-","A9553-","A9554-","G9555-","T9556-","A9557-","T9558-","T9559-","T9560-","A9561-","C9562-","A9563-","T9564-","T9565-","T9566-","T9567-","T9568-","C9569-","A9570-","C9571-","T9572-","G9573-","T9574-","T9575-","T9576-","A9577-","G9578-","T9579-","C9580-","G9581-","C9582-","G9583-","G9584-","A9585-","T9586-","A9587-","T9588-","G9589-","G9590-","A9591-","A9592-","T9593-","T9594-","C9595-","G9596-","A9597-","T9598-","C9599-","C9600-","T9601-","G9602-","T9603-","C9604-","A9605-","A9606-","A9607-","A9608-","T9609-","C9610-","A9611-","A9612-","T9613-","A9614-","C9615-","A9616-","T9617-","C9618-","A9619-","T9620-","C9621-","T9622-","A9623-","T9624-","A9625-","G9626-","A9627-","T9628-","C9629-","A9630-","T9631-","G9632-","T9633-","A9634-","A9635-","C9636-","A9637-","A9638-","T9639-","A9640-","T9641-","T9642-","A9643-","C9644-","A9645-","A9646-","T9647-","A9648-","C9649-","A9650-","T9651-","A9652-","G9653-","A9654-","T9655-","G9656-","A9657-","A9658-","C9659-","C9660-","A9661-","A9662-","A9663-","T9664-","G9665-","A9666-","T9667-","A9668-","T9669-","A9670-","A9671-","G9672-","A9673-","C9674-","T9675-","A9676-","A9677-","C9678-","A9679-","G9680-","T9681-","A9682-","T9683-","G9684-","C9685-","A9686-","T9687-","T9688-","A9689-","T9690-","C9691-","C9692-","G9693-","A9694-","A9695-","A9696-","T9697-","G9698-","T9699-","T9700-","A9701-","A9702-","T9703-","A9704-","A9705-","C9706-","A9707-","T9708-","T9709-","A9710-","C9711-","A9712-","T9713-","A9714-","T9715-","T9716-","A9717-","T9718-","A9719-","T9720-","C9721-","A9722-","A9723-","T9724-","A9725-","T9726-","C9727-","A9728-","C9729-","A9730-","A9731-","A9732-","A9733-","A9734-","T9735-","A9736-","A9737-","A9738-","T9739-","C9740-","C9741-","A9742-","C9743-","A9744-","T9745-","T9746-","T9747-","G9748-","G9749-","C9750-","T9751-","A9752-","A9753-","T9754-","C9755-","G9756-","A9757-","T9758-","T9759-","T9760-","C9761-","G9762-","G9763-","G9764-","C9765-","T9766-","T9767-","G9768-","G9769-","A9770-","A9771-","A9772-","A9773-","A9774-","A9775-","C9776-","G9777-","T9778-","A9779-","T9780-","C9781-","G9782-","C9783-","C9784-","G9785-","G9786-","A9787-","A9788-","G9789-","G9790-","G9791-","A9792-","C9793-","T9794-","A9795-","T9796-","A9797-","T9798-","G9799-","A9800-","C9801-","T9802-","A9803-","A9804-","C9805-","T9806-","T9807-","A9808-","T9809-","C9810-","T9811-","A9812-","G9813-","A9814-","G9815-","A9816-","T9817-","A9818-","C9819-","A9820-","G9821-","G9822-","A9823-","A9824-","T9825-","A9826-","C9827-","A9828-","A9829-","C9830-","A9831-","A9832-","T9833-","C9834-","A9835-","A9836-","A9837-","A9838-","C9839-","T9840-","T9841-","A9842-","C9843-","T9844-","G9845-","A9846-","A9847-","A9848-","C9849-","T9850-","A9851-","T9852-","A9853-","C9854-","G9855-","T9856-","A9857-","A9858-","C9859-","T9860-","G9861-","T9862-","C9863-","A9864-","A9865-","A9866-","A9867-","A9868-","A9869-","A9870-","T9871-","A9872-","A9873-","A9874-","A9875-","A9876-","C9877-","A9878-","T9879-","A9880-","T9881-","A9882-","T9883-","G9884-","G9885-","T9886-","C9887-","T9888-","A9889-","T9890-","A9891-","T9892-","A9893-","T9894-","A9895-","C9896-","A9897-","C9898-","T9899-","A9900-","C9901-","A9902-","A9903-","T9904-","T9905-","T9906-","A9907-","G9908-","T9909-","T9910-","A9911-","T9912-","T9913-","A9914-","A9915-","T9916-","G9917-","T9918-","G9919-","G9920-","T9921-","T9922-","A9923-","T9924-","T9925-","G9926-","A9927-","T9928-","T9929-","G9930-","G9931-","A9932-","T9933-","A9934-","A9935-","C9936-","C9937-","G9938-","A9939-","T9940-","G9941-","T9942-","G9943-","A9944-","T9945-","T9946-","G9947-","T9948-","T9949-","C9950-","A9951-","A9952-","T9953-","C9954-","A9955-","A9956-","T9957-","A9958-","T9959-","T9960-","A9961-","A9962-","G9963-","A9964-","G9965-","G9966-","G9967-","T9968-","T9969-","G9970-","G9971-","T9972-","A9973-","A9974-","A9975-","T9976-","T9977-","G9978-","G9979-","T9980-","A9981-","C9982-","A9983-","T9984-","A9985-","G9986-","C9987-","T9988-","A9989-","A9990-","T9991-","A9992-","A9993-","T9994-","A9995-","C9996-","A9997-","T9998-","A9999-","T10000-","A10001-","C10002-","T10003-","C10004-","C10005-","A10006-","A10007-","A10008-","T10009-","A10010-","C10011-","A10012-","C10013-","C10014-","C10015-","A10016-","A10017-","T10018-","A10019-","A10020-","T10021-","A10022-","C10023-","T10024-","A10025-","C10026-","A10027-","A10028-","C10029-","C10030-","A10031-","T10032-","T10033-","T10034-","C10035-","T10036-","G10037-","A10038-","G10039-","T10040-","T10041-","G10042-","G10043-","A10044-","T10045-","A10046-","T10047-","C10048-","A10049-","T10050-","C10051-","A10052-","A10053-","A10054-","A10055-","T10056-","A10057-","C10058-","T10059-","G10060-","G10061-","A10062-","T10063-","A10064-","A10065-","A10066-","T10067-","A10068-","C10069-","G10070-","A10071-","G10072-","G10073-","A10074-","C10075-","A10076-","T10077-","G10078-","T10079-","A10080-","T10081-","A10082-","G10083-","A10084-","G10085-","T10086-","A10087-","A10088-","G10089-","T10090-","A10091-","A10092-","A10093-","G10094-","A10095-","A10096-","A10097-","A10098-","A10099-","G10100-","A10101-","A10102-","T10103-","G10104-","T10105-","G10106-","G10107-","A10108-","A10109-","T10110-","T10111-","T10112-","G10113-","C10114-","T10115-","A10116-","T10117-","G10118-","A10119-","A10120-","G10121-","T10122-","T10123-","G10124-","T10125-","T10126-","T10127-","A10128-","C10129-","T10130-","C10131-","A10132-","A10133-","A10134-","A10135-","C10136-","G10137-","A10138-","T10139-","T10140-","A10141-","G10142-","A10143-","A10144-","A10145-","A10146-","C10147-","G10148-","A10149-","T10150-","A10151-","G10152-","A10153-","T10154-","A10155-","C10156-","T10157-","T10158-","T10159-","G10160-","G10161-","T10162-","T10163-","T10164-","A10165-","T10166-","T10167-","G10168-","G10169-","A10170-","T10171-","T10172-","C10173-","G10174-","T10175-","G10176-","T10177-","A10178-","A10179-","T10180-","C10181-","A10182-","T10183-","A10184-","T10185-","A10186-","T10187-","T10188-","T10189-","T10190-","G10191-","C10192-","A10193-","T10194-","A10195-","A10196-","C10197-","A10198-","T10199-","G10200-","T10201-","A10202-","T10203-","C10204-","A10205-","A10206-","T10207-","A10208-","T10209-","A10210-","T10211-","G10212-","G10213-","C10214-","A10215-","T10216-","A10217-","G10218-","A10219-","A10220-","C10221-","A10222-","C10223-","G10224-","A10225-","A10226-","G10227-","A10228-","G10229-","A10230-","A10231-","A10232-","C10233-","C10234-","G10235-","G10236-","T10237-","G10238-","C10239-","G10240-","T10241-","C10242-","A10243-","G10244-","A10245-","T10246-","A10247-","A10248-","T10249-","T10250-","G10251-","T10252-","C10253-","C10254-","T10255-","A10256-","T10257-","A10258-","T10259-","G10260-","C10261-","C10262-","G10263-","T10264-","A10265-","C10266-","A10267-","C10268-","G10269-","T10270-","T10271-","T10272-","T10273-","A10274-","A10275-","A10276-","A10277-","A10278-","A10279-","A10280-","T10281-","A10282-","A10283-","C10284-","A10285-","A10286-","T10287-","G10288-","A10289-","G10290-","C10291-","A10292-","A10293-","G10294-","T10295-","T10296-","C10297-","T10298-","A10299-","T10300-","A10301-","A10302-","G10303-","C10304-","T10305-","A10306-","G10307-","T10308-","T10309-","A10310-","A10311-","C10312-","T10313-","A10314-","A10315-","T10316-","A10317-","A10318-","A10319-","T10320-","A10321-","A10322-","A10323-","A10324-","A10325-","G10326-","T10327-","T10328-","T10329-","A10330-","A10331-","T10332-","T10333-","A10334-","T10335-","C10336-","G10337-","A10338-","C10339-","G10340-","A10341-","T10342-","A10343-","T10344-","A10345-","T10346-","G10347-","T10348-","C10349-","G10350-","T10351-","T10352-","A10353-","T10354-","T10355-","T10356-","T10357-","T10358-","C10359-","T10360-","C10361-","T10362-","C10363-","A10364-","T10365-","A10366-","T10367-","G10368-","A10369-","A10370-","A10371-","G10372-","A10373-","T10374-","T10375-","A10376-","A10377-","T10378-","T10379-","T10380-","G10381-","A10382-","T10383-","T10384-","C10385-","T10386-","A10387-","A10388-","T10389-","A10390-","T10391-","A10392-","A10393-","T10394-","C10395-","T10396-","T10397-","C10398-","A10399-","G10400-","T10401-","A10402-","T10403-","T10404-","G10405-","G10406-","A10407-","T10408-","G10409-","A10410-","A10411-","T10412-","C10413-","T10414-","C10415-","A10416-","A10417-","T10418-","T10419-","C10420-","A10421-","A10422-","A10423-","T10424-","T10425-","A10426-","A10427-","T10428-","T10429-","C10430-","C10431-","A10432-","T10433-","T10434-","A10435-","G10436-","A10437-","T10438-","T10439-","A10440-","G10441-","A10442-","T10443-","T10444-","A10445-","G10446-","A10447-","T10448-","T10449-","A10450-","G10451-","A10452-","T10453-","C10454-","A10455-","T10456-","A10457-","A10458-","A10459-","T10460-","A10461-","A10462-","A10463-","A10464-","A10465-","T10466-","A10467-","G10468-","T10469-","A10470-","G10471-","C10472-","A10473-","C10474-","G10475-","C10476-","A10477-","C10478-","T10479-","A10480-","C10481-","T10482-","T10483-","C10484-","A10485-","G10486-","C10487-","C10488-","A10489-","A10490-","A10491-","T10492-","A10493-","T10494-","T10495-","C10496-","T10497-","T10498-","T10499-","T10500-","T10501-","T10502-","G10503-","A10504-","A10505-","A10506-","C10507-","G10508-","C10509-","C10510-","A10511-","T10512-","C10513-","T10514-","A10515-","G10516-","C10517-","G10518-","T10519-","A10520-","A10521-","T10522-","G10523-","A10524-","G10525-","A10526-","A10527-","C10528-","A10529-","C10530-","A10531-","A10532-","G10533-","T10534-","G10535-","A10536-","A10537-","C10538-","C10539-","T10540-","A10541-","T10542-","A10543-","A10544-","T10545-","G10546-","A10547-","G10548-","C10549-","A10550-","A10551-","A10552-","T10553-","T10554-","T10555-","A10556-","T10557-","T10558-","A10559-","G10560-","T10561-","A10562-","T10563-","C10564-","G10565-","G10566-","T10567-","T10568-","A10569-","C10570-","A10571-","T10572-","G10573-","A10574-","A10575-","G10576-","G10577-","A10578-","C10579-","T10580-","T10581-","T10582-","A10583-","C10584-","G10585-","T10586-","A10587-","G10588-","A10589-","G10590-","T10591-","G10592-","G10593-","T10594-","G10595-","A10596-","T10597-","T10598-","C10599-","C10600-","T10601-","C10602-","C10603-","A10604-","T10605-","C10606-","T10607-","G10608-","T10609-","G10610-","G10611-","T10612-","A10613-","C10614-","G10615-","A10616-","A10617-","C10618-","G10619-","G10620-","T10621-","T10622-","T10623-","C10624-","A10625-","T10626-","C10627-","T10628-","T10629-","C10630-","T10631-","T10632-","T10633-","G10634-","A10635-","T10636-","G10637-","C10638-","C10639-","A10640-","C10641-","C10642-","A10643-","C10644-","C10645-","C10646-","A10647-","G10648-","A10649-","T10650-","G10651-","T10652-","T10653-","C10654-","T10655-","A10656-","T10657-","A10658-","A10659-","A10660-","C10661-","T10662-","T10663-","G10664-","G10665-","T10666-","A10667-","T10668-","C10669-","C10670-","T10671-","C10672-","G10673-","T10674-","C10675-","C10676-","G10677-","A10678-","T10679-","T10680-","T10681-","C10682-","A10683-","T10684-","A10685-","T10686-","C10687-","A10688-","T10689-","T10690-","T10691-","G10692-","C10693-","C10694-","A10695-","A10696-","C10697-","C10698-","A10699-","A10700-","T10701-","A10702-","C10703-","A10704-","T10705-","A10706-","T10707-","A10708-","G10709-","C10710-","T10711-","A10712-","A10713-","A10714-","C10715-","C10716-","C10717-","A10718-","G10719-","G10720-","C10721-","A10722-","T10723-","A10724-","C10725-","G10726-","T10727-","T10728-","C10729-","C10730-","A10731-","C10732-","A10733-","C10734-","A10735-","T10736-","C10737-","C10738-","G10739-","G10740-","A10741-","A10742-","C10743-","A10744-","A10745-","T10746-","G10747-","A10748-","A10749-","A10750-","T10751-","T10752-","C10753-","T10754-","C10755-","C10756-","A10757-","G10758-","A10759-","A10760-","G10761-","A10762-","T10763-","G10764-","T10765-","T10766-","A10767-","C10768-","A10769-","A10770-","T10771-","G10772-","G10773-","C10774-","T10775-","A10776-","G10777-","A10778-","T10779-","T10780-","T10781-","G10782-","G10783-","A10784-","C10785-","A10786-","T10787-","T10788-","T10789-","G10790-","G10791-","T10792-","T10793-","T10794-","C10795-","A10796-","A10797-","C10798-","C10799-","G10800-","C10801-","G10802-","T10803-","T10804-","A10805-","A10806-","C10807-","A10808-","T10809-","A10810-","T10811-","G10812-","A10813-","G10814-","T10815-","G10816-","A10817-","A10818-","C10819-","A10820-","C10821-","A10822-","C10823-","C10824-","C10825-","A10826-","T10827-","A10828-","C10829-","A10830-","T10831-","G10832-","A10833-","A10834-","A10835-","G10836-","C10837-","G10838-","A10839-","T10840-","G10841-","A10842-","G10843-","A10844-","A10845-","A10846-","T10847-","A10848-","G10849-","G10850-","A10851-","T10852-","T10853-","C10854-","T10855-","C10856-","A10857-","T10858-","C10859-","T10860-","T10861-","G10862-","C10863-","C10864-","A10865-","A10866-","A10867-","A10868-","T10869-","A10870-","T10871-","C10872-","A10873-","C10874-","T10875-","A10876-","T10877-","A10878-","A10879-","A10880-","A10881-","A10882-","A10883-","T10884-","T10885-","T10886-","A10887-","T10888-","T10889-","T10890-","A10891-","T10892-","C10893-","A10894-","A10895-","T10896-","T10897-","T10898-","T10899-","A10900-","A10901-","A10902-","G10903-","G10904-","T10905-","A10906-","T10907-","A10908-","A10909-","A10910-","A10911-","A10912-","A10913-","A10914-","T10915-","A10916-","C10917-","T10918-","T10919-","A10920-","T10921-","T10922-","G10923-","T10924-","T10925-","G10926-","C10927-","T10928-","C10929-","G10930-","A10931-","A10932-","T10933-","A10934-","T10935-","T10936-","T10937-","T10938-","G10939-","T10940-","A10941-","T10942-","T10943-","T10944-","G10945-","A10946-","T10947-","G10948-","G10949-","T10950-","A10951-","T10952-","A10953-","C10954-","G10955-","G10956-","A10957-","A10958-","G10959-","A10960-","T10961-","T10962-","A10963-","G10964-","A10965-","A10966-","A10967-","T10968-","G10969-","T10970-","A10971-","G10972-","G10973-","T10974-","A10975-","T10976-","T10977-","A10978-","T10979-","C10980-","A10981-","T10982-","C10983-","A10984-","A10985-","C10986-","T10987-","G10988-","A10989-","T10990-","T10991-","T10992-","T10993-","A10994-","T10995-","G10996-","A10997-","T10998-","G10999-","G11000-","T11001-","T11002-","T11003-","T11004-","A11005-","T11006-","G11007-","A11008-","A11009-","T11010-","T11011-","T11012-","T11013-","A11014-","T11015-","T11016-","A11017-","T11018-","G11019-","C11020-","T11021-","T11022-","C11023-","A11024-","C11025-","T11026-","A11027-","T11028-","T11029-","G11030-","C11031-","A11032-","T11033-","C11034-","G11035-","G11036-","A11037-","A11038-","A11039-","T11040-","A11041-","A11042-","T11043-","A11044-","T11045-","C11046-","A11047-","T11048-","A11049-","T11050-","G11051-","C11052-","T11053-","T11054-","C11055-","C11056-","A11057-","C11058-","G11059-","T11060-","A11061-","T11062-","A11063-","T11064-","T11065-","T11066-","T11067-","A11068-","T11069-","T11070-","T11071-","T11072-","G11073-","T11074-","T11075-","T11076-","T11077-","G11078-","A11079-","C11080-","T11081-","C11082-","A11083-","T11084-","A11085-","A11086-","T11087-","A11088-","C11089-","G11090-","C11091-","A11092-","C11093-","G11094-","T11095-","A11096-","A11097-","T11098-","T11099-","C11100-","T11101-","G11102-","G11103-","A11104-","T11105-","T11106-","A11107-","T11108-","T11109-","G11110-","G11111-","C11112-","A11113-","T11114-","A11115-","T11116-","C11117-","G11118-","A11119-","T11120-","G11121-","A11122-","A11123-","T11124-","A11125-","A11126-","T11127-","T11128-","T11129-","T11130-","A11131-","G11132-","C11133-","T11134-","C11135-","C11136-","A11137-","T11138-","G11139-","C11140-","T11141-","C11142-","A11143-","G11144-","T11145-","A11146-","A11147-","A11148-","T11149-","A11150-","T11151-","T11152-","A11153-","A11154-","T11155-","G11156-","A11157-","G11158-","A11159-","A11160-","C11161-","A11162-","T11163-","A11164-","G11165-","T11166-","G11167-","T11168-","T11169-","G11170-","C11171-","C11172-","T11173-","C11174-","C11175-","T11176-","A11177-","C11178-","C11179-","A11180-","T11181-","T11182-","A11183-","T11184-","T11185-","T11186-","T11187-","T11188-","T11189-","T11190-","C11191-","A11192-","T11193-","C11194-","T11195-","C11196-","A11197-","T11198-","T11199-","C11200-","A11201-","A11202-","T11203-","T11204-","C11205-","T11206-","T11207-","G11208-","A11209-","T11210-","T11211-","G11212-","C11213-","A11214-","G11215-","A11216-","G11217-","A11218-","T11219-","C11220-","T11221-","A11222-","T11223-","A11224-","T11225-","A11226-","A11227-","T11228-","C11229-","A11230-","T11231-","T11232-","A11233-","T11234-","A11235-","G11236-","C11237-","G11238-","T11239-","T11240-","G11241-","A11242-","C11243-","T11244-","T11245-","A11246-","T11247-","G11248-","G11249-","A11250-","C11251-","T11252-","C11253-","T11254-","G11255-","G11256-","A11257-","A11258-","T11259-","C11260-","T11261-","T11262-","A11263-","G11264-","A11265-","C11266-","G11267-","A11268-","T11269-","G11270-","T11271-","A11272-","C11273-","A11274-","G11275-","T11276-","C11277-","A11278-","T11279-","C11280-","T11281-","A11282-","T11283-","A11284-","A11285-","T11286-","C11287-","A11288-","T11289-","G11290-","G11291-","T11292-","A11293-","T11294-","A11295-","T11296-","T11297-","T11298-","A11299-","A11300-","T11301-","A11302-","C11303-","A11304-","T11305-","T11306-","G11307-","T11308-","T11309-","T11310-","T11311-","A11312-","T11313-","A11314-","G11315-","C11316-","A11317-","T11318-","A11319-","G11320-","G11321-","C11322-","A11323-","T11324-","T11325-","A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","C11727T","C39139T","-173314A","-173315T","-173316A","-173317T","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A185259-","G185260-","A185261-","A185262-","T185263-","G185264-","T185265-","T185266-","T185267-","G185268-","C185269-","C185270-","A185271-","C185272-","A185273-","T185274-","T185275-","G185276-","G185277-","C185278-","T185279-","A185280-","G185281-","A185282-","G185283-","G185284-","A185285-","A185286-","T185287-","G185288-","C185289-","C185290-","G185291-","T185292-","T185293-","T185294-","A185295-","G185296-","A185297-","T185298-","C185299-","A185300-","A185301-","C185302-","G185303-","T185304-","A185305-","T185306-","T185307-","G185308-","C185309-","G185310-","A185311-","T185312-","A185313-","A185314-","C185315-","A185316-","G185317-","A185318-","C185319-","G185320-","A185321-","C185322-","G185323-","A185324-","T185325-","C185326-","A185327-","G185328-","G185329-","T185330-","T185331-","G185332-","T185333-","T185334-","A185335-","T185336-","T185337-","A185338-","T185339-","G185340-","C185341-","A185342-","G185343-","G185344-","A185345-","A185346-","T185347-","A185348-","C185349-","C185350-","A185351-","T185352-","T185353-","T185354-","C185355-","A185356-","T185357-","G185358-","A185359-","A185360-","G185361-","A185362-","T185363-","A185364-","G185365-","T185366-","G185367-","T185368-","A185369-","G185370-","A185371-","A185372-","A185373-","C185374-","A185375-","G185376-","A185377-","T185378-","A185379-","T185380-","A185381-","C185382-","A185383-","T185384-","T185385-","A185386-","T185387-","G185388-","G185389-","A185390-","C185391-","C185392-","A185393-","G185394-","A185395-","A185396-","A185397-","T185398-","A185399-","A185400-","T185401-","G185402-","T185403-","T185404-","A185405-","A185406-","A185407-","G185408-","G185409-","A185410-","A185411-","A185412-","C185413-","A185414-","T185415-","A185416-","T185417-","G185418-","A185419-","C185420-","A185421-","T185422-","A185423-","A185424-","A185425-","C185426-","A185427-","G185428-","T185429-","A185430-","T185431-","T185432-","G185433-","A185434-","C185435-","C185436-","C185437-","A185438-","C185439-","G185440-","A185441-","G185442-","T185443-","T185444-","A185445-","T185446-","A185447-","A185448-","C185449-","A185450-","A185451-","A185452-","G185453-","T185454-","C185455-","A185456-","A185457-","A185458-","G185459-","A185460-","C185461-","C185462-","C185463-","A185464-","T185465-","T185466-","T185467-","T185468-","C185469-","C185470-","T185471-","G185472-","C185473-","T185474-","C185475-","C185476-","A185477-","T185478-","T185479-","G185480-","A185481-","G185482-","T185483-","G185484-","T185485-","A185486-","A185487-","A185488-","A185489-","T185490-","T185491-","C185492-","A185493-","T185494-","G185495-","G185496-","T185497-","T185498-","G185499-","A185500-","C185501-","A185502-","A185503-","T185504-","T185505-","T185506-","A185507-","G185508-","G185509-","A185510-","A185511-","A185512-","T185513-","G185514-","G185515-","A185516-","T185517-","A185518-","T185519-","G185520-","A185521-","C185522-","A185523-","A185524-","C185525-","C185526-","C185527-","T185528-","A185529-","A185530-","T185531-","T185532-","C185533-","A185534-","T185535-","T185536-","T185537-","T185538-","G185539-","G185540-","G185541-","A185542-","A185543-","G185544-","A185545-","T185546-","G185547-","C185548-","T185549-","A185550-","A185551-","A185552-","A185553-","C185554-","T185555-","A185556-","A185557-","G185558-","A185559-","A185560-","A185561-","C185562-","G185563-","G185564-","A185565-","C185566-","A185567-","T185568-","A185569-","T185570-","A185571-","G185572-","T185573-","G185574-","C185575-","A185576-","A185577-","T185578-","G185579-","A185580-","C185581-","G185582-","A185583-","T185584-","A185585-","A185586-","A185587-","A185588-","G185589-","T185590-","C185591-","C185592-","T185593-","A185594-","C185595-","C185596-","A185597-","T185598-","G185599-","T185600-","A185601-","C185602-","A185603-","G185604-","T185605-","G185606-","A185607-","G185608-","A185609-","A185610-","A185611-","T185612-","A185613-","A185614-","A185615-","A185616-","A185617-","T185618-","A185619-","T185620-","A185621-","G185622-","A185623-","C185624-","T185625-","T185626-","T185627-","G185628-","G185629-","A185630-","T185631-","A185632-","T185633-","A185634-","A185635-","C185636-","T185637-","A185638-","T185639-","G185640-","G185641-","A185642-","G185643-","A185644-","T185645-","A185646-","T185647-","T185648-","A185649-","T185650-","T185651-","T185652-","C185653-","T185654-","A185655-","A185656-","T185657-","A185658-","T185659-","G185660-","G185661-","T185662-","T185663-","T185664-","A185665-","T185666-","C185667-","T185668-","A185669-","C185670-","A185671-","A185672-","T185673-","C185674-","T185675-","A185676-","C185677-","T185678-","A185679-","G185680-","T185681-","C185682-","A185683-","G185684-","G185685-","A185686-","T185687-","T185688-","A185689-","T185690-","G185691-","G185692-","A185693-","G185694-","A185695-","T185696-","G185697-","G185698-","T185699-","A185700-","C185701-","C185702-","A185703-","A185704-","A185705-","T185706-","A185707-","T185708-","A185709-","C185710-","A185711-","T185712-","T185713-","T185714-","A185715-","A185716-","A185717-","T185718-","C185719-","C185720-","G185721-","T185722-","A185723-","A185724-","C185725-","T185726-","A185727-","G185728-","A185729-","T185730-","C185731-","A185732-","G185733-","A185734-","T185735-","C185736-","A185737-","T185738-","G185739-","A185740-","G185741-","T185742-","G185743-","T185744-","G185745-","A185746-","A185747-","T185748-","C185749-","T185750-","A185751-","G185752-","C185753-","T185754-","T185755-","A185756-","G185757-","A185758-","T185759-","C185760-","T185761-","A185762-","A185763-","C185764-","G185765-","T185766-","C185767-","T185768-","A185769-","A185770-","G185771-","G185772-","A185773-","A185774-","G185775-","T185776-","A185777-","A185778-","C185779-","T185780-","G185781-","T185782-","G185783-","A185784-","C185785-","A185786-","T185787-","G185788-","T185789-","C185790-","C185791-","T185792-","G185793-","C185794-","G185795-","T185796-","T185797-","T185798-","A185799-","G185800-","T185801-","A185802-","T185803-","A185804-","C185805-","C185806-","A185807-","A185808-","G185809-","A185810-","A185811-","A185812-","T185813-","A185814-","T185815-","A185816-","T185817-","C185818-","A185819-","A185820-","C185821-","A185822-","T185823-","A185824-","T185825-","G185826-","A185827-","A185828-","G185829-","G185830-","T185831-","C185832-","T185833-","A185834-","T185835-","G185836-","C185837-","T185838-","T185839-","T185840-","A185841-","G185842-","T185843-","G185844-","T185845-","T185846-","A185847-","C185848-","T185849-","A185850-","C185851-","A185852-","T185853-","C185854-","T185855-","A185856-","A185857-","A185858-","G185859-","A185860-","T185861-","C185862-","A185863-","T185864-","T185865-","G185866-","T185867-","G185868-","C185869-","T185870-","A185871-","C185872-","A185873-","G185874-","G185875-","T185876-","A185877-","T185878-","T185879-","G185880-","G185881-","T185882-","T185883-","G185884-","G185885-","T185886-","T185887-","A185888-","A185889-","A185890-","A185891-","T185892-","C185893-","T185894-","A185895-","G185896-","T185897-","G185898-","G185899-","T185900-","T185901-","A185902-","T185903-","G185904-","G185905-","G185906-","A185907-","A185908-","G185909-","G185910-","A185911-","A185912-","G185913-","A185914-","T185915-","G185916-","C185917-","T185918-","G185919-","A185920-","T185921-","A185922-","A185923-","A185924-","C185925-","C185926-","A185927-","C185928-","G185929-","T185930-","G185931-","C185932-","T185933-","T185934-","G185935-","T185936-","T185937-","T185938-","T185939-","C185940-","A185941-","T185942-","C185943-","A185944-","T185945-","T185946-","G185947-","G185948-","A185949-","A185950-","T185951-","T185952-","A185953-","T185954-","T185955-","A185956-","C185957-","A185958-","C185959-","A185960-","C185961-","T185962-","G185963-","T185964-","C185965-","G185966-","T185967-","T185968-","G185969-","G185970-","A185971-","T185972-","T185973-","A185974-","T185975-","T185976-","A185977-","C185978-","T185979-","G185980-","T185981-","T185982-","C185983-","A185984-","T185985-","A185986-","C185987-","G185988-","A185989-","A185990-","G185991-","A185992-","T185993-","A185994-","T185995-","T185996-","T185997-","G185998-","G185999-","A186000-","G186001-","A186002-","A186003-","G186004-","C186005-","A186006-","C186007-","C186008-","T186009-","G186010-","G186011-","C186012-","C186013-","T186014-","G186015-","A186016-","C186017-","T186018-","A186019-","T186020-","G186021-","A186022-","T186023-","C186024-","C186025-","A186026-","T186027-","G186028-","T186029-","A186030-","A186031-","G186032-","T186033-","C186034-","A186035-","T186036-","A186037-","T186038-","A186039-","T186040-","C186041-","C186042-","A186043-","T186044-","A186045-","T186046-","A186047-","G186048-","A186049-","G186050-","T186051-","A186052-","T186053-","A186054-","G186055-","A186056-","G186057-","A186058-","T186059-","A186060-","C186061-","A186062-","T186063-","G186064-","G186065-","A186066-","T186067-","A186068-","G186069-","A186070-","A186071-","T186072-","C186073-","T186074-","A186075-","A186076-","T186077-","G186078-","T186079-","G186080-","T186081-","T186082-","A186083-","C186084-","A186085-","G186086-","C186087-","A186088-","A186089-","C186090-","C186091-","T186092-","C186093-","C186094-","T186095-","T186096-","A186097-","C186098-","A186099-","C186100-","A186101-","T186102-","T186103-","C186104-","G186105-","A186106-","A186107-","T186108-","T186109-","C186110-","A186111-","T186112-","T186113-","C186114-","A186115-","T186116-","G186117-","A186118-","C186119-","A186120-","A186121-","T186122-","T186123-","C186124-","T186125-","A186126-","A186127-","C186128-","G186129-","A186130-","A186131-","T186132-","A186133-","T186134-","G186135-","T186136-","G186137-","G186138-","A186139-","T186140-","A186141-","A186142-","A186143-","G186144-","A186145-","A186146-","A186147-","T186148-","T186149-","A186150-","G186151-","T186152-","A186153-","A186154-","C186155-","A186156-","A186157-","A186158-","T186159-","T186160-","A186161-","A186162-","A186163-","T186164-","G186165-","A186166-","T186167-","C186168-","T186169-","G186170-","T186171-","A186172-","C186173-","A186174-","A186175-","T186176-","G186177-","A186178-","A186179-","T186180-","A186181-","C186182-","A186183-","A186184-","G186185-","A186186-","A186187-","G186188-","A186189-","T186190-","T186191-","A186192-","T186193-","G186194-","G186195-","A186196-","A186197-","T186198-","A186199-","T186200-","A186201-","G186202-","C186203-","G186204-","A186205-","C186206-","G186207-","G186208-","A186209-","T186210-","C186211-","A186212-","T186213-","T186214-","G186215-","C186216-","C186217-","G186218-","G186219-","C186220-","G186221-","T186222-","C186223-","T186224-","A186225-","T186226-","A186227-","A186228-","A186229-","C186230-","A186231-","G186232-","A186233-","T186234-","T186235-","A186236-","G186237-","C186238-","A186239-","A186240-","A186241-","G186242-","G186243-","C186244-","A186245-","T186246-","T186247-","G186248-","A186249-","C186250-","T186251-","T186252-","C186253-","A186254-","G186255-","A186256-","G186257-","G186258-","G186259-","T186260-","A186261-","G186262-","A186263-","G186264-","A186265-","A186266-","A186267-","T186268-","A186269-","G186270-","C186271-","A186272-","A186273-","G186274-","T186275-","G186276-","T186277-","T186278-","A186279-","A186280-","T186281-","A186282-","T186283-","A186284-","G186285-","A186286-","T186287-","G186288-","G186289-","T186290-","A186291-","A186292-","T186293-","C186294-","T186295-","G186296-","T186297-","T186298-","A186299-","G186300-","A186301-","T186302-","A186303-","T186304-","C186305-","G186306-","C186307-","A186308-","T186309-","A186310-","T186311-","C186312-","A186313-","A186314-","G186315-","C186316-","A186317-","G186318-","A186319-","T186320-","A186321-","A186322-","G186323-","G186324-","A186325-","A186326-","A186327-","A186328-","G186329-","A186330-","T186331-","G186332-","G186333-","C186334-","C186335-","G186336-","A186337-","C186338-","A186339-","T186340-","A186341-","C186342-","A186343-","G186344-","A186345-","C186346-","A186347-","A186348-","G186349-","A186350-","A186351-","T186352-","A186353-","A186354-","A186355-","T186356-","G186357-","A186358-","T186359-","A186360-","T186361-","T186362-","A186363-","T186364-","T186365-","A186366-","G186367-","A186368-","G186369-","A186370-","T186371-","T186372-","T186373-","G186374-","T186375-","T186376-","T186377-","A186378-","T186379-","A186380-","C186381-","A186382-","C186383-","A186384-","C186385-","T186386-","C186387-","T186388-","A186389-","T186390-","C186391-","A186392-","G186393-","A186394-","C186395-","A186396-","A186397-","A186398-","G186399-","A186400-","T186401-","A186402-","T186403-","A186404-","A186405-","A186406-","A186407-","G186408-","A186409-","C186410-","A186411-","T186412-","T186413-","A186414-","T186415-","A186416-","G186417-","A186418-","A186419-","T186420-","C186421-","C186422-","G186423-","A186424-","A186425-","G186426-","A186427-","A186428-","G186429-","G186430-","T186431-","A186432-","A186433-","G186434-","A186435-","G186436-","A186437-","T186438-","G186439-","T186440-","T186441-","G186442-","T186443-","A186444-","T186445-","A186446-","A186447-","T186448-","A186449-","G186450-","A186451-","T186452-","G186453-","T186454-","T186455-","A186456-","A186457-","G186458-","A186459-","A186460-","C186461-","A186462-","A186463-","T186464-","C186465-","T186466-","T186467-","G186468-","T186469-","T186470-","A186471-","A186472-","A186473-","A186474-","A186475-","G186476-","T186477-","A186478-","C186479-","T186480-","A186481-","T186482-","T186483-","C186484-","T186485-","A186486-","T186487-","T186488-","G186489-","A186490-","T186491-","A186492-","A186493-","T186494-","T186495-","A186496-","T186497-","C186498-","T186499-","A186500-","T186501-","G186502-","T186503-","G186504-","A186505-","T186506-","A186507-","C186508-","T186509-","T186510-","T186511-","A186512-","G186513-","A186514-","T186515-","G186516-","A186517-","T186518-","T186519-","A186520-","T186521-","A186522-","T186523-","A186524-","T186525-","A186526-","C186527-","A186528-","C186529-","C186530-","T186531-","C186532-","T186533-","G186534-","T186535-","A186536-","G186537-","A186538-","A186539-","T186540-","A186541-","T186542-","A186543-","A186544-","C186545-","A186546-","A186547-","A186548-","T186549-","C186550-","C186551-","T186552-","A186553-","T186554-","G186555-","T186556-","G186557-","T186558-","T186559-","A186560-","G186561-","T186562-","A186563-","A186564-","A186565-","C186566-","G186567-","A186568-","T186569-","A186570-","C186571-","T186572-","T186573-","A186574-","T186575-","A186576-","T186577-","G186578-","A186579-","G186580-","C186581-","T186582-","A186583-","T186584-","G186585-","A186586-","C186587-","T186588-","A186589-","T186590-","C186591-","T186592-","T186593-","G186594-","A186595-","A186596-","T186597-","C186598-","A186599-","T186600-","C186601-","A186602-","G186603-","G186604-","T186605-","G186606-","T186607-","A186608-","G186609-","T186610-","T186611-","G186612-","T186613-","T186614-","C186615-","T186616-","A186617-","T186618-","C186619-","A186620-","T186621-","G186622-","T186623-","T186624-","A186625-","T186626-","G186627-","A186628-","A186629-","A186630-","T186631-","G186632-","A186633-","C186634-","T186635-","A186636-","T186637-","A186638-","A186639-","T186640-","C186641-","T186642-","C186643-","C186644-","T186645-","T186646-","G186647-","G186648-","A186649-","T186650-","A186651-","C186652-","A186653-","A186654-","A186655-","A186656-","G186657-","A186658-","C186659-","G186660-","C186661-","C186662-","A186663-","A186664-","A186665-","G186666-","A186667-","T186668-","G186669-","C186670-","T186671-","A186672-","T186673-","A186674-","G186675-","A186676-","A186677-","G186678-","A186679-","T186680-","G186681-","T186682-","G186683-","A186684-","T186685-","A186686-","G186687-","T186688-","A186689-","G186690-","C186691-","A186692-","A186693-","G186694-","T186695-","G186696-","C186697-","G186698-","G186699-","T186700-","A186701-","G186702-","C186703-","C186704-","G186705-","A186706-","A186707-","G186708-","C186709-","A186710-","T186711-","T186712-","G186713-","A186714-","A186715-","T186716-","G186717-","A186718-","C186719-","A186720-","T186721-","G186722-","T186723-","T186724-","T186725-","A186726-","A186727-","G186728-","G186729-","A186730-","A186731-","T186732-","T186733-","T186734-","G186735-","A186736-","T186737-","A186738-","A186739-","A186740-","A186741-","A186742-","C186743-","G186744-","T186745-","A186746-","A186747-","G186748-","T186749-","G186750-","C186751-","T186752-","A186753-","T186754-","T186755-","A186756-","T186757-","A186758-","A186759-","T186760-","A186761-","A186762-","A186763-","A186764-","G186765-","A186766-","A186767-","G186768-","A186769-","A186770-","G186771-","A186772-","T186773-","A186774-","A186775-","T186776-","T186777-","A186778-","T186779-","C186780-","T186781-","A186782-","A186783-","A186784-","C186785-","A186786-","G186787-","T186788-","T186789-","C186790-","G186791-","C186792-","C186793-","C186794-","G186795-","A186796-","T186797-","A186798-","T186799-","C186800-","T186801-","A186802-","C186803-","C186804-","A186805-","T186806-","A186807-","T186808-","A186809-","A186810-","T186811-","A186812-","T186813-","A186814-","T186815-","A186816-","T186817-","C186818-","A186819-","T186820-","A186821-","G186822-","G186823-","T186824-","G186825-","G186826-","C186827-","A186828-","C186829-","T186830-","A186831-","T186832-","T186833-","C186834-","T186835-","G186836-","C186837-","T186838-","A186839-","C186840-","T186841-","G186842-","T186843-","T186844-","A186845-","G186846-","T186847-","C186848-","A186849-","T186850-","T186851-","A186852-","T186853-","T186854-","T186855-","T186856-","A186857-","A186858-","T186859-","A186860-","T186861-","T186862-","G186863-","G186864-","C186865-","A186866-","A186867-","T186868-","T186869-","T186870-","A186871-","T186872-","A186873-","T186874-","A186875-","G186876-","C186877-","G186878-","C186879-","G186880-","C186881-","A186882-","A186883-","T186884-","A186885-","A186886-","A186887-","T186888-","A186889-","C186890-","A186891-","G186892-","A186893-","A186894-","C186895-","C186896-","A186897-","G186898-","G186899-","A186900-","A186901-","A186902-","T186903-","A186904-","T186905-","G186906-","A186907-","A186908-","A186909-","T186910-","A186911-","A186912-","T186913-","G186914-","A186915-","A186916-","A186917-","T186918-","A186919-","T186920-","G186921-","A186922-","C186923-","A186924-","A186925-","T186926-","A186927-","T186928-","G186929-","A186930-","G186931-","C186932-","A186933-","T186934-","T186935-","A186936-","A186937-","A186938-","T186939-","C186940-","T186941-","G186942-","A186943-","G186944-","C186945-","A186946-","T186947-","C186948-","A186949-","T186950-","G186951-","A186952-","T186953-","A186954-","G186955-","T186956-","C186957-","T186958-","T186959-","G186960-","A186961-","A186962-","A186963-","C186964-","A186965-","G186966-","T186967-","G186968-","T186969-","C186970-","T186971-","A186972-","T186973-","G186974-","G186975-","A186976-","A186977-","A186978-","T186979-","T186980-","A186981-","T186982-","T186983-","G186984-","A186985-","T186986-","A186987-","A186988-","T186989-","C186990-","G186991-","G186992-","T186993-","A186994-","C186995-","T186996-","A186997-","A186998-","T186999-","A187000-","A187001-","A187002-","A187003-","T187004-","A187005-","G187006-","T187007-","T187008-","T187009-","A187010-","A187011-","C187012-","T187013-","C187014-","T187015-","T187016-","T187017-","T187018-","A187019-","G187020-","A187021-","A187022-","C187023-","C187024-","A187025-","G187026-","T187027-","T187028-","T187029-","G187030-","G187031-","T187032-","A187033-","C187034-","T187035-","G187036-","T187037-","A187038-","A187039-","T187040-","T187041-","T187042-","C187043-","A187044-","G187045-","T187046-","T187047-","C187048-","A187049-","T187050-","T187051-","A187052-","C187053-","T187054-","C187055-","G187056-","T187057-","T187058-","G187059-","A187060-","G187061-","A187062-","A187063-","T187064-","A187065-","T187066-","T187067-","G187068-","A187069-","T187070-","G187071-","A187072-","T187073-","T187074-","T187075-","T187076-","T187077-","T187078-","T187079-","T187080-","A187081-","A187082-","A187083-","T187084-","G187085-","A187086-","G187087-","T187088-","A187089-","T187090-","C187091-","G187092-","G187093-","T187094-","A187095-","G187096-","T187097-","T187098-","A187099-","C187100-","A187101-","T187102-","A187103-","T187104-","T187105-","A187106-","C187107-","C187108-","A187109-","T187110-","A187111-","T187112-","C187113-","A187114-","T187115-","C187116-","C187117-","A187118-","T187119-","T187120-","A187121-","T187122-","A187123-","T187124-","A187125-","A187126-","T187127-","C187128-","G187129-","A187130-","T187131-","G187132-","A187133-","T187134-","G187135-","C187136-","A187137-","T187138-","G187139-","T187140-","A187141-","T187142-","T187143-","A187144-","G187145-","A187146-","A187147-","T187148-","A187149-","C187150-","T187151-","T187152-","T187153-","C187154-","C187155-","G187156-","A187157-","A187158-","T187159-","A187160-","A187161-","G187162-","T187163-","C187164-","T187165-","T187166-","C187167-","T187168-","A187169-","A187170-","A187171-","T187172-","A187173-","T187174-","T187175-","G187176-","T187177-","A187178-","T187179-","T187180-","A187181-","A187182-","T187183-","T187184-","A187185-","T187186-","G187187-","A187188-","A187189-","A187190-","A187191-","A187192-","C187193-","T187194-","A187195-","T187196-","G187197-","C187198-","T187199-","A187200-","T187201-","G187202-","T187203-","G187204-","A187205-","G187206-","T187207-","A187208-","T187209-","G187210-","A187211-","T187212-","T187213-","C187214-","A187215-","A187216-","A187217-","G187218-","A187219-","T187220-","G187221-","T187222-","T187223-","T187224-","A187225-","A187226-","T187227-","G187228-","A187229-","T187230-","A187231-","C187232-","G187233-","A187234-","T187235-","A187236-","C187237-","T187238-","A187239-","G187240-","A187241-","T187242-","T187243-","T187244-","T187245-","A187246-","T187247-","C187248-","T187249-","C187250-","T187251-","A187252-","G187253-","C187254-","G187255-","A187256-","G187257-","A187258-","T187259-","T187260-","G187261-","T187262-","T187263-","T187264-","A187265-","G187266-","A187267-","A187268-","T187269-","C187270-","A187271-","T187272-","T187273-","T187274-","A187275-","T187276-","C187277-","A187278-","T187279-","A187280-","A187281-","C187282-","T187283-","A187284-","T187285-","G187286-","T187287-","T187288-","T187289-","A187290-","A187291-","T187292-","A187293-","A187294-","A187295-","T187296-","T187297-","C187298-","A187299-","T187300-","C187301-","A187302-","A187303-","C187304-","G187305-","A187306-","A187307-","T187308-","A187309-","T187310-","C187311-","G187312-","A187313-","T187314-","A187315-","A187316-","A187317-","G187318-","A187319-","C187320-","C187321-","T187322-","C187323-","T187324-","T187325-","G187326-","T187327-","A187328-","A187329-","T187330-","T187331-","C187332-","G187333-","A187334-","G187335-","T187336-","A187337-","T187338-","A187339-","G187340-","G187341-","A187342-","A187343-","G187344-","T187345-","A187346-","G187347-","T187348-","A187349-","T187350-","T187351-","A187352-","C187353-","C187354-","A187355-","T187356-","A187357-","T187358-","C187359-","A187360-","A187361-","C187362-","T187363-","T187364-","C187365-","C187366-","G187367-","A187368-","G187369-","T187370-","T187371-","A187372-","A187373-","C187374-","A187375-","A187376-","T187377-","T187378-","A187379-","C187380-","T187381-","C187382-","T187383-","A187384-","A187385-","A187386-","A187387-","C187388-","A187389-","T187390-","G187391-","A187392-","G187393-","G187394-","A187395-","T187396-","T187397-","G187398-","T187399-","A187400-","C187401-","T187402-","C187403-","C187404-","T187405-","G187406-","T187407-","C187408-","T187409-","T187410-","T187411-","A187412-","T187413-","T187414-","G187415-","G187416-","A187417-","G187418-","A187419-","T187420-","C187421-","A187422-","C187423-","T187424-","A187425-","T187426-","T187427-","T187428-","A187429-","G187430-","T187431-","C187432-","G187433-","T187434-","T187435-","G187436-","A187437-","T187438-","A187439-","A187440-","A187441-","C187442-","T187443-","A187444-","G187445-","T187446-","A187447-","A187448-","C187449-","C187450-","T187451-","C187452-","A187453-","G187454-","G187455-","T187456-","T187457-","T187458-","C187459-","T187460-","T187461-","T187462-","A187463-","C187464-","A187465-","A187466-","A187467-","C187468-","G187469-","A187470-","T187471-","A187472-","A187473-","A187474-","G187475-","T187476-","A187477-","C187478-","A187479-","A187480-","C187481-","A187482-","T187483-","C187484-","A187485-","A187486-","G187487-","A187488-","C187489-","C187490-","T187491-","C187492-","A187493-","C187494-","A187495-","A187496-","C187497-","A187498-","C187499-","A187500-","G187501-","T187502-","G187503-","C187504-","A187505-","A187506-","G187507-","A187508-","T187509-","T187510-","A187511-","A187512-","T187513-","C187514-","T187515-","A187516-","G187517-","A187518-","A187519-","A187520-","T187521-","C187522-","A187523-","A187524-","A187525-","T187526-","G187527-","T187528-","A187529-","A187530-","T187531-","T187532-","C187533-","T187534-","G187535-","G187536-","A187537-","G187538-","G187539-","A187540-","G187541-","A187542-","A187543-","T187544-","C187545-","T187546-","A187547-","G187548-","A187549-","C187550-","A187551-","A187552-","C187553-","T187554-","A187555-","A187556-","C187557-","A187558-","C187559-","C187560-","C187561-","A187562-","C187563-","G187564-","G187565-","C187566-","G187567-","A187568-","A187569-","G187570-","T187571-","A187572-","T187573-","A187574-","C187575-","T187576-","T187577-","T187578-","A187579-","T187580-","G187581-","C187582-","C187583-","T187584-","C187585-","A187586-","T187587-","T187588-","C187589-","A187590-","G187591-","A187592-","A187593-","A187594-","C187595-","G187596-","G187597-","T187598-","A187599-","A187600-","C187601-","T187602-","G187603-","T187604-","A187605-","G187606-","T187607-","A187608-","G187609-","G187610-","A187611-","G187612-","A187613-","C187614-","T187615-","G187616-","T187617-","C187618-","T187619-","C187620-","T187621-","C187622-","T187623-","A187624-","A187625-","T187626-","C187627-","T187628-","C187629-","G187630-","A187631-","T187632-","G187633-","T187634-","A187635-","T187636-","A187637-","T187638-","A187639-","T187640-","A187641-","A187642-","T187643-","A187644-","T187645-","A187646-","T187647-","A187648-","C187649-","C187650-","A187651-","A187652-","T187653-","A187654-","C187655-","G187656-","G187657-","A187658-","C187659-","G187660-","C187661-","G187662-","A187663-","T187664-","A187665-","T187666-","A187667-","T187668-","T187669-","C187670-","C187671-","G187672-","A187673-","C187674-","A187675-","T187676-","G187677-","A187678-","A187679-","T187680-","G187681-","G187682-","C187683-","G187684-","T187685-","C187686-","G187687-","C187688-","T187689-","T187690-","A187691-","T187692-","C187693-","A187694-","T187695-","A187696-","T187697-","G187698-","T187699-","T187700-","A187701-","T187702-","A187703-","T187704-","C187705-","C187706-","T187707-","A187708-","A187709-","A187710-","T187711-","G187712-","T187713-","T187714-","G187715-","A187716-","T187717-","C187718-","A187719-","T187720-","A187721-","T187722-","T187723-","C187724-","C187725-","A187726-","C187727-","A187728-","A187729-","A187730-","T187731-","G187732-","A187733-","T187734-","T187735-","G187736-","T187737-","G187738-","A187739-","A187740-","C187741-","G187742-","A187743-","G187744-","A187745-","T187746-","T187747-","A187748-","A187749-","A187750-","T187751-","C187752-","A187753-","T187754-","C187755-","T187756-","A187757-","A187758-","C187759-","A187760-","A187761-","A187762-","T187763-","A187764-","A187765-","T187766-","T187767-","A187768-","G187769-","T187770-","T187771-","T187772-","T187773-","T187774-","T187775-","A187776-","T187777-","G187778-","A187779-","C187780-","A187781-","T187782-","T187783-","A187784-","A187785-","C187786-","A187787-","T187788-","A187789-","T187790-","A187791-","A187792-","T187793-","A187794-","A187795-","A187796-","T187797-","A187798-","A187799-","A187800-","T187801-","T187802-","A187803-","A187804-","T187805-","C187806-","A187807-","T187808-","T187809-","A187810-","T187811-","T187812-","G187813-","A187814-","C187815-","T187816-","T187817-","A187818-","A187819-","C187820-","G187821-","A187822-","T187823-","G187824-","A187825-","C187826-","G187827-","A187828-","A187829-","A187830-","G187831-","T187832-","T187833-","A187834-","T187835-","C187836-","A187837-","T187838-","T187839-","A187840-","T187841-","C187842-","T187843-","T187844-","A187845-","G187846-","G187847-","A187848-","T187849-","T187850-","C187851-","T187852-","T187853-","G187854-","A187855-","T187856-","T187857-","A187858-","T187859-","T187860-","A187861-","A187862-","T187863-","A187864-","C187865-","A187866-","A187867-","A187868-","T187869-","T187870-","C187871-","G187872-","T187873-","T187874-","G187875-","T187876-","G187877-","T187878-","C187879-","T187880-","A187881-","T187882-","G187883-","A187884-","A187885-","A187886-","T187887-","G187888-","T187889-","G187890-","A187891-","A187892-","C187893-","A187894-","A187895-","G187896-","G187897-","T187898-","G187899-","T187900-","C187901-","T187902-","C187903-","A187904-","T187905-","A187906-","T187907-","T187908-","A187909-","T187910-","A187911-","A187912-","T187913-","G187914-","C187915-","A187916-","C187917-","A187918-","A187919-","G187920-","A187921-","A187922-","T187923-","T187924-","A187925-","A187926-","A187927-","G187928-","T187929-","G187930-","T187931-","T187932-","G187933-","T187934-","A187935-","A187936-","A187937-","C187938-","T187939-","A187940-","T187941-","C187942-","T187943-","A187944-","G187945-","C187946-","C187947-","A187948-","G187949-","G187950-","A187951-","A187952-","C187953-","A187954-","T187955-","A187956-","T187957-","T187958-","C187959-","A187960-","G187961-","A187962-","T187963-","T187964-","A187965-","T187966-","C187967-","G187968-","A187969-","T187970-","G187971-","T187972-","G187973-","A187974-","T187975-","A187976-","A187977-","A187978-","T187979-","A187980-","C187981-","A187982-","G187983-","C187984-","G187985-","A187986-","T187987-","A187988-","C187989-","C187990-","A187991-","T187992-","C187993-","T187994-","G187995-","T187996-","G187997-","G187998-","A187999-","C188000-","A188001-","T188002-","T188003-","G188004-","T188005-","C188006-","C188007-","A188008-","A188009-","G188010-","T188011-","G188012-","A188013-","C188014-","A188015-","C188016-","A188017-","T188018-","T188019-","C188020-","A188021-","C188022-","G188023-","T188024-","C188025-","A188026-","A188027-","T188028-","A188029-","T188030-","A188031-","T188032-","A188033-","A188034-","T188035-","C188036-","G188037-","T188038-","T188039-","C188040-","T188041-","C188042-","C188043-","T188044-","C188045-","G188046-","G188047-","T188048-","G188049-","T188050-","C188051-","A188052-","T188053-","A188054-","G188055-","T188056-","T188057-","G188058-","T188059-","A188060-","G188061-","A188062-","G188063-","G188064-","T188065-","C188066-","A188067-","C188068-","A188069-","C188070-","C188071-","T188072-","T188073-","G188074-","T188075-","A188076-","C188077-","A188078-","C188079-","C188080-","T188081-","A188082-","C188083-","C188084-","A188085-","C188086-","A188087-","A188088-","A188089-","T188090-","A188091-","G188092-","A188093-","A188094-","T188095-","A188096-","T188097-","G188098-","T188099-","C188100-","A188101-","T188102-","T188103-","G188104-","T188105-","G188106-","A188107-","C188108-","T188109-","C188110-","G188111-","A188112-","A188113-","T188114-","A188115-","G188116-","T188117-","T188118-","A188119-","T188120-","C188121-","G188122-","T188123-","C188124-","T188125-","C188126-","C188127-","T188128-","T188129-","A188130-","A188131-","A188132-","G188133-","C188134-","T188135-","T188136-","C188137-","T188138-","G188139-","A188140-","T188141-","G188142-","G188143-","T188144-","A188145-","A188146-","C188147-","T188148-","G188149-","T188150-","G188151-","T188152-","T188153-","A188154-","C188155-","A188156-","T188157-","G188158-","T188159-","G188160-","C188161-","T188162-","C188163-","C188164-","T188165-","A188166-","A188167-","A188168-","A188169-","C188170-","A188171-","A188172-","A188173-","A188174-","T188175-","A188176-","T188177-","G188178-","G188179-","T188180-","C188181-","G188182-","T188183-","G188184-","T188185-","G188186-","T188187-","A188188-","C188189-","G188190-","G188191-","A188192-","A188193-","A188194-","G188195-","A188196-","A188197-","A188198-","G188199-","G188200-","A188201-","G188202-","A188203-","A188204-","A188205-","A188206-","T188207-","G188208-","A188209-","T188210-","A188211-","T188212-","G188213-","G188214-","A188215-","A188216-","T188217-","A188218-","C188219-","C188220-","A188221-","T188222-","T188223-","T188224-","G188225-","T188226-","A188227-","A188228-","G188229-","A188230-","A188231-","A188232-","T188233-","G188234-","T188235-","C188236-","G188237-","G188238-","A188239-","A188240-","G188241-","G188242-","G188243-","T188244-","A188245-","C188246-","T188247-","T188248-","A188249-","T188250-","T188251-","C188252-","A188253-","G188254-","A188255-","T188256-","A188257-","T188258-","T188259-","G188260-","T188261-","A188262-","T188263-","C188264-","T188265-","G188266-","A188267-","C188268-","T188269-","C188270-","T188271-","G188272-","A188273-","T188274-","C188275-","A188276-","A188277-","T188278-","G188279-","T188280-","A188281-","A188282-","A188283-","C188284-","C188285-","T188286-","A188287-","T188288-","G188289-","A188290-","C188291-","A188292-","A188293-","G188294-","A188295-","T188296-","A188297-","A188298-","G188299-","A188300-","C188301-","T188302-","T188303-","A188304-","C188305-","T188306-","C188307-","G188308-","C188309-","A188310-","T188311-","C188312-","T188313-","A188314-","C188315-","T188316-","G188317-","G188318-","A188319-","T188320-","A188321-","G188322-","A188323-","C188324-","A188325-","T188326-","A188327-","A188328-","A188329-","T188330-","A188331-","T188332-","C188333-","C188334-","T188335-","C188336-","C188337-","T188338-","C188339-","G188340-","T188341-","A188342-","A188343-","T188344-","A188345-","A188346-","T188347-","G188348-","A188349-","A188350-","A188351-","T188352-","A188353-","T188354-","A188355-","A188356-","T188357-","A188358-","T188359-","A188360-","C188361-","A188362-","C188363-","T188364-","A188365-","A188366-","T188367-","T188368-","A188369-","T188370-","T188371-","A188372-","A188373-","T188374-","A188375-","T188376-","C188377-","A188378-","A188379-","T188380-","C188381-","G188382-","A188383-","G188384-","T188385-","A188386-","T188387-","T188388-","A188389-","A188390-","C188391-","A188392-","T188393-","A188394-","T188395-","A188396-","A188397-","G188398-","T188399-","T188400-","A188401-","T188402-","T188403-","T188404-","T188405-","T188406-","A188407-","A188408-","A188409-","C188410-","C188411-","C188412-","C188413-","T188414-","T188415-","T188416-","T188417-","G188418-","G188419-","G188420-","T188421-","T188422-","C188423-","C188424-","G188425-","T188426-","C188427-","C188428-","T188429-","A188430-","A188431-","A188432-","C188433-","G188434-","G188435-","C188436-","G188437-","T188438-","T188439-","T188440-","C188441-","G188442-","G188443-","T188444-","C188445-","T188446-","G188447-","T188448-","G188449-","T188450-","C188451-","G188452-","C188453-","C188454-","A188455-","C188456-","C188457-","A188458-","T188459-","G188460-","G188461-","T188462-","C188463-","A188464-","C188465-","A188466-","C188467-","C188468-","G188469-","A188470-","G188471-","C188472-","C188473-","T188474-","C188475-","T188476-","G188477-","C188478-","G188479-","T188480-","G188481-","C188482-","T188483-","C188484-","C188485-","T188486-","C188487-","C188488-","A188489-","T188490-","C188491-","G188492-","A188493-","G188494-","G188495-","A188496-","C188497-","G188498-","A188499-","C188500-","T188501-","T188502-","C188503-","A188504-","A188505-","C188506-","T188507-","A188508-","T188509-","G188510-","A188511-","C188512-","A188513-","G188514-","C188515-","T188516-","C188517-","G188518-","G188519-","T188520-","G188521-","G188522-","C188523-","G188524-","T188525-","C188526-","T188527-","G188528-","C188529-","C188530-","A188531-","G188532-","C188533-","G188534-","T188535-","G188536-","T188537-","A188538-","C188539-","A188540-","T188541-","A188542-","C188543-","G188544-","A188545-","A188546-","T188547-","G188548-","G188549-","C188550-","A188551-","T188552-","T188553-","T188554-","C188555-","T188556-","A188557-","A188558-","G188559-","A188560-","A188561-","A188562-","A188563-","G188564-","T188565-","C188566-","T188567-","A188568-","C188569-","G188570-","G188571-","T188572-","A188573-","T188574-","C188575-","C188576-","T188577-","T188578-","T188579-","C188580-","T188581-","A188582-","C188583-","A188584-","A188585-","T188586-","T188587-","T188588-","C188589-","C188590-","T188591-","T188592-","T188593-","A188594-","A188595-","C188596-","A188597-","A188598-","C188599-","G188600-","G188601-","C188602-","A188603-","A188604-","C188605-","A188606-","G188607-","C188608-","T188609-","G188610-","C188611-","A188612-","G188613-","T188614-","A188615-","T188616-","T188617-","T188618-","T188619-","T188620-","A188621-","T188622-","A188623-","C188624-","T188625-","T188626-","T188627-","G188628-","A188629-","A188630-","T188631-","G188632-","C188633-","A188634-","T188635-","C188636-","G188637-","G188638-","A188639-","C188640-","A188641-","T188642-","T188643-","T188644-","A188645-","T188646-","A188647-","C188648-","A188649-","A188650-","G188651-","G188652-","G188653-","A188654-","G188655-","T188656-","C188657-","C188658-","T188659-","G188660-","T188661-","T188662-","C188663-","T188664-","A188665-","A188666-","T188667-","A188668-","T188669-","T188670-","G188671-","G188672-","C188673-","A188674-","T188675-","C188676-","A188677-","A188678-","T188679-","G188680-","T188681-","T188682-","C188683-","G188684-","G188685-","A188686-","T188687-","C188688-","T188689-","A188690-","T188691-","A188692-","G188693-","G188694-","C188695-","T188696-","T188697-","G188698-","A188699-","T188700-","T188701-","T188702-","T188703-","C188704-","G188705-","C188706-","A188707-","T188708-","T188709-","G188710-","A188711-","C188712-","T188713-","T188714-","T188715-","A188716-","C188717-","A188718-","C188719-","A188720-","G188721-","A188722-","C188723-","A188724-","T188725-","G188726-","A188727-","A188728-","C188729-","A188730-","T188731-","C188732-","C188733-","C188734-","C188735-","T188736-","G188737-","A188738-","A188739-","T188740-","C188741-","T188742-","G188743-","T188744-","A188745-","C188746-","A188747-","T188748-","A188749-","C188750-","T188751-","T188752-","T188753-","G188754-","T188755-","G188756-","G188757-","A188758-","T188759-","T188760-","T188761-","A188762-","C188763-","A188764-","C188765-","T188766-","G188767-","T188768-","T188769-","A188770-","G188771-","A188772-","A188773-","T188774-","C188775-","T188776-","C188777-","T188778-","A188779-","A188780-","C188781-","G188782-","C188783-","T188784-","G188785-","G188786-","C188787-","C188788-","T188789-","C188790-","T188791-","G188792-","T188793-","T188794-","G188795-","T188796-","T188797-","A188798-","C188799-","T188800-","T188801-","T188802-","C188803-","T188804-","A188805-","T188806-","G188807-","A188808-","T188809-","G188810-","C188811-","A188812-","C188813-","G188814-","T188815-","A188816-","T188817-","C188818-","G188819-","T188820-","T188821-","A188822-","T188823-","G188824-","C188825-","A188826-","A188827-","G188828-","C188829-","T188830-","T188831-","T188832-","C188833-","A188834-","T188835-","G188836-","T188837-","T188838-","G188839-","A188840-","C188841-","T188842-","A188843-","C188844-","T188845-","G188846-","C188847-","A188848-","G188849-","T188850-","G188851-","T188852-","T188853-","T188854-","C188855-","T188856-","T188857-","G188858-","C188859-","T188860-","C188861-","T188862-","G188863-","A188864-","C188865-","T188866-","A188867-","C188868-","A188869-","T188870-","A188871-","T188872-","A188873-","C188874-","T188875-","C188876-","T188877-","A188878-","C188879-","A188880-","A188881-","T188882-","C188883-","A188884-","A188885-","A188886-","G188887-","A188888-","G188889-","A188890-","G188891-","A188892-","T188893-","T188894-","T188895-","C188896-","A188897-","G188898-","T188899-","A188900-","A188901-","A188902-","C188903-","T188904-","T188905-","G188906-","T188907-","A188908-","A188909-","C188910-","A188911-","G188912-","G188913-","A188914-","T188915-","T188916-","G188917-","T188918-","T188919-","T188920-","G188921-","C188922-","T188923-","G188924-","C188925-","T188926-","T188927-","T188928-","C188929-","T188930-","G188931-","G188932-","A188933-","T188934-","-196616A"],"OPG023":["D392N"],"OPG057":["E353K"]},"labels":{"aa":"OPG023: D392N; OPG057: E353K"}}},{"name":"OP612674","node_attrs":{"div":519,"accession":"OP612674","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"lineage":{"value":"A.1"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP612674/2019-01-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV/003/19"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-01-12"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C11555T","G28645A","G75967A","T76087-","G94840A","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","C188503T","A196612-","A196613-","A196614-","A196615-"],"OPG023":["R449Q"],"OPG115":["E61K"]},"labels":{"aa":"OPG023: R449Q; OPG115: E61K"}}},{"name":"NODE_0000082","node_attrs":{"div":515,"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G1126A","G2039A","T76087-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","C195171T","C196084T"],"OPG002":["S238L"],"OPG002_dup":["S238L"]},"labels":{"aa":"OPG002: S238L; OPG002_dup: S238L"}},"children":[{"name":"OP612688","node_attrs":{"div":523,"accession":"OP612688","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"lineage":{"value":"A.1"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP612688/2019-11-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV/104/19"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-11-02"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","G2152A","C6948T","C47224T","C77726T","C143845T","G152431A","C166786T","G184037T","C184535T","C195058T"],"OPG066":["E69K"],"OPG099":["S21F"],"OPG192":["S19L"]},"labels":{"aa":"OPG066: E69K; OPG099: S21F; OPG192: S19L"}}},{"name":"OP612682","node_attrs":{"div":518,"accession":"OP612682","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"lineage":{"value":"A.1"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP612682/2019-04-20"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV/040/19"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-04-20"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C69017T","C150406T","G182196A","-196616A","-196617A"],"OPG087":["S54F"],"OPG210":["D281N"]},"labels":{"aa":"OPG087: S54F; OPG210: D281N"}}}]},{"name":"NODE_0000083","node_attrs":{"div":515,"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G151929A","-196616A"],"OPG178":["E141K"]},"labels":{"aa":"OPG178: E141K"}},"children":[{"name":"OL504743","node_attrs":{"div":523,"accession":"OL504743","author":{"author":"Atkinson,B.,Pottage,T.,Ngabo,D.,Crook,A.,Pitman,J.,Summers,S.,Pullan,S.,Lewandowski,K.,Furneaux,J.,Davies,K.,Brooks,T.","value":"Atkinson,B.,Pottage,T.,Ngabo,D.,Crook,A.,Pitman,J.,Summers,S.,Pullan,S.,Lewandowski,K.,Furneaux,J.,Davies,K.,Brooks,T."},"lineage":{"value":"A.1"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OL504743/2019-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"2102"},"institution":{"value":"UKHSA, Research"},"date":{"value":"2019-12-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C5477G","C13065T","C29887T","G61329A","C72206T","G103431A","C165369T","-173314A","-173315T","-173316A","-173317T","C179172-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G188949A","A191442G"],"OPG015":["R227P"],"OPG015_dup":["E130G"],"OPG024":["G55E"],"OPG092":["E248K"],"OPG123":["S547L"],"OPG190":["S83F"]},"labels":{"aa":"OPG015: R227P; OPG015_dup: E130G; OPG024: G55E; OPG092: E248K; OPG123: S547L; OPG190: S83F"}}},{"name":"NODE_0000084","node_attrs":{"div":516,"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C39767T","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A"]}},"children":[{"name":"MT903342","node_attrs":{"div":518,"accession":"MT903342","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"lineage":{"value":"A.1"},"country":{"value":"Singapore"},"strain_display":{"value":"Singapore/MT903342/2019-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MPXV-Singapore"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-608T","C43927T","C170573T","-173314A","-173315T","-173316A","-173317T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"],"OPG064":["E658K"],"OPG198":["S179L"]},"labels":{"aa":"OPG064: E658K; OPG198: S179L"}}},{"name":"OP612685","node_attrs":{"div":516,"accession":"OP612685","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"lineage":{"value":"A.1"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP612685/2019-05-29"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV/052/19"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-05-29"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-","A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","-196617A"]}}}]}]},{"name":"NODE_0000085","node_attrs":{"div":516,"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G25661A","C39119T","-173314A","-173315T","-173316A","-173317T"]}},"children":[{"name":"OP612679","node_attrs":{"div":524,"accession":"OP612679","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"lineage":{"value":"A.1"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP612679/2019-03-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV/018/19"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-03-14"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C8500T","G79538A","G81354A","G84416A","C88736T","G100642A","C138791T","C161616T","-196616A","-196617A"],"OPG102":["D152N"],"OPG105":["E77K"],"OPG109":["E238K"],"OPG119":["R86K"],"OPG156":["D207N"]},"labels":{"aa":"OPG102: D152N; OPG105: E77K; OPG109: E238K; OPG119: R86K; OPG156: D207N"}}},{"name":"NODE_0000086","node_attrs":{"div":517,"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T607-","G162243A","C179172-","A196615-"]}},"children":[{"name":"MT903345","node_attrs":{"div":517,"accession":"MT903345","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"lineage":{"value":"A.1"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/MT903345/2018-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV-UK_P3"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"MT903344","node_attrs":{"div":517,"accession":"MT903344","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"lineage":{"value":"A.1"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/MT903344/2018-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV-UK_P2"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"]}}},{"name":"NODE_0000087","node_attrs":{"div":520,"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G1262A","C3818T","G124130A","C128698T","T133099-","T133177-","C133178-","T133179-","T133180-","T133181-","C133182-","T133183-","C133184-","A133185-","A133186-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179177T","-179178A","G193392A","C195948T"],"OPG001":["S105L"],"OPG001_dup":["S105L"],"OPG003":["D264N"],"OPG003_dup":["D264N"],"OPG145":["E62K"],"OPG150":["S307L"]},"labels":{"aa":"OPG001: S105L; OPG001_dup: S105L; OPG003: D264N; OPG003_dup: D264N; OPG145: E62K; OPG150: S307L"}},"children":[{"name":"OP612687","node_attrs":{"div":525,"accession":"OP612687","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"lineage":{"value":"A.1"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP612687/2019-07-11"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV/058/19"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-07-11"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","C756T","G2039A","G168365A","A173288-","T173289-","-179172C","-179173A","-179174T","-179175T","-179176A","C188605A","A188606C","G188607A","T193455A","C195171T","G196454-","A196614-"],"OPG002":["S238L"],"OPG002_dup":["S238L"],"OPG003_dup":["L285I"],"OPG195":["E46K"]},"labels":{"aa":"OPG002: S238L; OPG002_dup: S238L; OPG003_dup: L285I; OPG195: E46K"}}},{"name":"NODE_0000088","node_attrs":{"div":521,"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G81275A"]}},"children":[{"name":"OP612686","node_attrs":{"div":522,"accession":"OP612686","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"lineage":{"value":"A.1"},"country":{"value":"Nigeria"},"strain_display":{"value":"Nigeria/OP612686/2019-06-26"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"MPXV/053/19"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-06-26"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","T76087-","G88640A","-179172C","-179173A","-179174T","-179175T","-179176A","-196615A","-196616A","-196617A"],"OPG109":["R270C"]},"labels":{"aa":"OPG109: R270C"}}},{"name":"NODE_0000089","node_attrs":{"div":546,"lineage":{"value":"A.1.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G2591A","G3522A","C7771T","G14000T","G15428A","G21723A","G30367A","G31053A","G34459A","G37202A","G38360A","C38662T","G52885A","G54117A","G54635A","G64297A","C73066T","C82373T","G82451A","G95034A","G124674A","-133099T","C162331T","-173290A","-173291T","-173292A","-173293T","-173294A","-173295T","-173296A","-173297T","-173298A","-173299T","-173300A","-173301T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","G178133A","G181980A","G186578A","C193688T","C194619T"],"OPG002":["S54F"],"OPG002_dup":["S54F"],"OPG025":["A423D"],"OPG047":["R48C"],"OPG053":["P78S"],"OPG056":["E125K"],"OPG071":["L108F"],"OPG072":["D56N"],"OPG093":["S30L"],"OPG145":["R243Q"],"OPG210":["D209N","M1741I"]},"labels":{"aa":"OPG002: S54F; OPG002_dup: S54F; OPG025: A423D; OPG047: R48C; OPG053: P78S; OPG056: E125K; OPG071: L108F; OPG072: D56N; OPG093: S30L; OPG145: R243Q; OPG210: D209N, M1741I","clade":"A.1.1"}},"children":[{"name":"ON676708","node_attrs":{"div":549,"accession":"ON676708","author":{"author":"Gigante,C.M.,Myers,R.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Blythe,D.,Li,Y.","value":"Gigante,C.M.,Myers,R.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Blythe,D.,Li,Y."},"lineage":{"value":"A.1.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/ON676708/2021-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2021_MD"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2021-11-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C79348T","C86979T","C133714T","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"NODE_0000090","node_attrs":{"div":557,"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G3111A","C39139T","G73239A","G74205A","G77383A","C84587T","C150469T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A151461C","G155795A","G170262A","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C183519T","C194099T"],"OPG057":["E353K"],"OPG093":["D88N"],"OPG094":["M142I"],"OPG098":["E162K"],"OPG176":["H221Y"],"OPG210":["P722S"]},"labels":{"aa":"OPG057: E353K; OPG093: D88N; OPG094: M142I; OPG098: E162K; OPG176: H221Y; OPG210: P722S","clade":"B.1"}},"children":[{"name":"LC722946","node_attrs":{"div":560,"accession":"LC722946","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"B.1"},"country":{"value":"Japan"},"strain_display":{"value":"Japan/LC722946/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MPXV/human/Japan/Tokyo/TKY220091/2022"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C13653T","C116100T","G150376A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG025":["D539N"],"OPG176":["D190N"]},"labels":{"aa":"OPG025: D539N; OPG176: D190N"}}},{"name":"OP160532","node_attrs":{"div":558,"accession":"OP160532","author":{"author":"Tutu van Furth AM,van der Kuip M,van Els AL,Fievez LC,van Rijckevorsel GG,van den Ouden A,Jonges M,Welkers MR,Welkers,M.,Jonges,M.","value":"Tutu van Furth AM,van der Kuip M,van Els AL,Fievez LC,van Rijckevorsel GG,van den Ouden A,Jonges M,Welkers MR,Welkers,M.,Jonges,M."},"lineage":{"value":"B.1"},"country":{"value":"Netherlands"},"strain_display":{"value":"Netherlands/OP160532/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMpxV/Netherlands/NH-AUMC-0001/2022"},"institution":{"value":"Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A148207T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G191845A","A196614-"],"OPG173":["E57D"]},"labels":{"aa":"OPG173: E57D"}}},{"name":"OP133007","node_attrs":{"div":559,"accession":"OP133007","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"country":{"value":"Austria"},"strain_display":{"value":"Austria/OP133007/2022-07-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMPXV/Austria/MUW1536480/2022"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-22"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A28532-","G32715A","G110407A","T133099C","T133100-","T133101-","T133102-","C133103-","A173189G","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG044":["M148-"],"OPG049":["S146F"]},"labels":{"aa":"OPG044: M148-; OPG049: S146F"}}},{"name":"OP120937","node_attrs":{"div":558,"accession":"OP120937","author":{"author":"Aja-Macaya,P.,Rumbo-Feal,S.,Poza,M.,Canizares,A.,Vallejo,J.A.,Bou,G.","value":"Aja-Macaya,P.,Rumbo-Feal,S.,Poza,M.,Canizares,A.,Vallejo,J.A.,Bou,G."},"lineage":{"value":"B.1"},"country":{"value":"Spain"},"strain_display":{"value":"Spain/OP120937/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MP01CHUAC"},"institution":{"value":"Biomedical research institute (INIBIC), Microbiology"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G150330A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP018598","node_attrs":{"div":557,"accession":"OP018598","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP018598/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI173"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON927243","node_attrs":{"div":558,"accession":"ON927243","author":{"author":"Palomino-Cabrera,R.,Penas-Utrilla,D.,Buenestado-Serrano,S.,Perez-Lago,L.,Herranz Martin,M.,Veintimilla,C.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Palomino-Cabrera,R.,Penas-Utrilla,D.,Buenestado-Serrano,S.,Perez-Lago,L.,Herranz Martin,M.,Veintimilla,C.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"lineage":{"value":"B.1"},"country":{"value":"Spain"},"strain_display":{"value":"Spain/ON927243/2022-06-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MpxV/Spain/MD-HGUGM-6642566/2022"},"institution":{"value":"HGUGM, Microbial Genomics"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-21"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","C187154T"]}}},{"name":"ON872184","node_attrs":{"div":562,"accession":"ON872184","author":{"author":"Fletcher,N.,Gonzalez,G.,Meredith,L.,Purves,K.,Carr,M.,Dean,J.,Keogan,B.,Crowley,B.,Lyons,F.,O'Reilly,S.,Gautier,V.,Mallon,P.,Gordon,S.,Connell,J.,De Gascun,C.F.","value":"Fletcher,N.,Gonzalez,G.,Meredith,L.,Purves,K.,Carr,M.,Dean,J.,Keogan,B.,Crowley,B.,Lyons,F.,O'Reilly,S.,Gautier,V.,Mallon,P.,Gordon,S.,Connell,J.,De Gascun,C.F."},"lineage":{"value":"B.1"},"country":{"value":"Ireland"},"strain_display":{"value":"Ireland/ON872184/2022-05-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"WA-2022"},"institution":{"value":"University College Dublin, National Virus Reference Laboratory"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-30"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T48785C","G49636A","C50017T","T72809C","G178541A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG068":["G479E"],"OPG069":["T11I"],"OPG092":["K47E"]},"labels":{"aa":"OPG068: G479E; OPG069: T11I; OPG092: K47E"}}},{"name":"ON803421","node_attrs":{"div":557,"accession":"ON803421","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/ON803421/2022-05-19"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/CAN/UN-NML-2849/2022"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-19"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON676706","node_attrs":{"div":557,"accession":"ON676706","author":{"author":"Gigante,C.M.,Atkinson,A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Murray,J.,Li,Y.","value":"Gigante,C.M.,Atkinson,A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Murray,J.,Li,Y."},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/ON676706/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_UT002"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","T133099-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON649710","node_attrs":{"div":557,"accession":"ON649710","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/ON649710/2022-05-18"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0027/2022"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-18"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"ON644344","node_attrs":{"div":557,"accession":"ON644344","author":{"author":"Licastro,D.,DeGasperi,M.,Negri,C.,Piscianz,E.,Koncan,R.,Dal Monego,S.,Segat,L.,D'Agaro,P.","value":"Licastro,D.,DeGasperi,M.,Negri,C.,Piscianz,E.,Koncan,R.,Dal Monego,S.,Segat,L.,D'Agaro,P."},"lineage":{"value":"B.1"},"country":{"value":"Italy"},"strain_display":{"value":"Italy/ON644344/2022-05-25"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_FVG-ITA_01_2022"},"institution":{"value":"Genomics & Epigenomics, AREA Science Park, Italy"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-25"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C334-","A335-","C133077T","T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T173317-","G173318-","G173319-","G173320-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON619835","node_attrs":{"div":557,"accession":"ON619835","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/ON619835/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_UK_2022_1"},"institution":{"value":"Research & Evaluation, UKHSA, UK"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179179T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","T179244-"]}}},{"name":"ON615424","node_attrs":{"div":559,"accession":"ON615424","author":{"author":"Oude Munnink,B.B.,Boter,M.,Wellers,B.,Molenkamp,R.,Sikkema,R.S.,Koopmans,M.","value":"Oude Munnink,B.B.,Boter,M.,Wellers,B.,Molenkamp,R.,Sikkema,R.S.,Koopmans,M."},"lineage":{"value":"B.1"},"country":{"value":"Netherlands"},"strain_display":{"value":"Netherlands/ON615424/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_2022_NL001"},"institution":{"value":"Public Health Virology, Erasmus Medical Centre, The Netherlands"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155611A","G171003A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","G179362-","G179363-","-196615A"],"OPG199":["E6K"]},"labels":{"aa":"OPG199: E6K"}}},{"name":"ON595760","node_attrs":{"div":557,"accession":"ON595760","author":{"author":"Laubscher,F.,Chudzinski,V.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinski,V.,Schibler,M.,Kaiser,L.,Renzoni,A."},"lineage":{"value":"B.1"},"country":{"value":"Switzerland"},"strain_display":{"value":"Switzerland/ON595760/2022-05-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV-CH-38134631/2022"},"institution":{"value":"Laboratory of Viorology, University Hospital of Geneva, Switzerland"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-19"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","T133099-","T133100-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"]}}},{"name":"OP341487","node_attrs":{"div":561,"accession":"OP341487","author":{"author":"Welkers,M.,Jonges,M.,de Regt,M.,Ooijevaar,R.,Wagemakers,A.","value":"Welkers,M.,Jonges,M.,de Regt,M.,Ooijevaar,R.,Wagemakers,A."},"lineage":{"value":"B.1"},"country":{"value":"Netherlands"},"strain_display":{"value":"Netherlands/OP341487/2022-08-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMpxV/Netherlands/NH-AUMC-0060/2022"},"institution":{"value":"Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-05"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C96773T","C109432T","C114985T","C142356T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG117":["S242L"],"OPG129":["D525N"],"OPG133":["D238N"],"OPG163":["S52F"]},"labels":{"aa":"OPG117: S242L; OPG129: D525N; OPG133: D238N; OPG163: S52F"}}},{"name":"OP245323","node_attrs":{"div":557,"accession":"OP245323","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP245323/2022-07-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX/PT0069/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-27"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP215281","node_attrs":{"div":558,"accession":"OP215281","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP215281/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI262"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G184945A"],"OPG210":["R1197K"]},"labels":{"aa":"OPG210: R1197K"}}},{"name":"OP245316","node_attrs":{"div":558,"accession":"OP245316","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP245316/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX/PT0062/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C15652T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP422343","node_attrs":{"div":559,"accession":"OP422343","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"country":{"value":"Austria"},"strain_display":{"value":"Austria/OP422343/2022-08-08"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMPXV/Austria/MUW1540386/2022"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-08"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C102355T","C113923T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG121":["S189L"],"OPG133":["D592N"]},"labels":{"aa":"OPG121: S189L; OPG133: D592N"}}},{"name":"OP415196","node_attrs":{"div":557,"accession":"OP415196","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP415196/2022-03-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX_96X1Vd_9000218"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-03-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP415184","node_attrs":{"div":560,"accession":"OP415184","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP415184/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX_h9DUQg_9000203"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C59862T","G83097A","G148496A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG105":["D658N"]},"labels":{"aa":"OPG105: D658N"}}},{"name":"OP414304","node_attrs":{"div":559,"accession":"OP414304","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP414304/2022-06-17"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0264/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-17"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G33700A","A136552-","T136553-","C136554-","G150394A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG153":["D385-"],"OPG176":["E196K"]},"labels":{"aa":"OPG153: D385-; OPG176: E196K"}}},{"name":"OP536809","node_attrs":{"div":561,"accession":"OP536809","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP536809/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"9000444"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G100476A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159448A","G169832A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G185499A"],"OPG119":["V31I"],"OPG185":["D178N"],"OPG197":["E55K"],"OPG210":["D1382N"]},"labels":{"aa":"OPG119: V31I; OPG185: D178N; OPG197: E55K; OPG210: D1382N"}}},{"name":"OP536815","node_attrs":{"div":557,"accession":"OP536815","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP536815/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"9000453"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP605580","node_attrs":{"div":558,"accession":"OP605580","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"country":{"value":"Slovenia"},"strain_display":{"value":"Slovenia/OP605580/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Slovenia-MPXV-39-2022"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","C179082T","C179091T","T179094A","C179100T","T179103A","C179109T","T179112A","C179118T","T179121A","C179127T","T179130A","C179136T","C179145T","T179148A","C179154T","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179239A","-179240T","-179241A","-179242T","-179243A","G189288A"]}}},{"name":"OP587253","node_attrs":{"div":561,"accession":"OP587253","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP587253/2022-07-13"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-CDPH-MPX000024/2022"},"institution":{"value":"CDPH, VRDL"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-13"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","C138921A","A149457T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G174137A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C189536T"],"OPG005":["S113L"],"OPG153":["D385-"],"OPG175":["I6L"]},"labels":{"aa":"OPG005: S113L; OPG153: D385-; OPG175: I6L"}}},{"name":"OP555634","node_attrs":{"div":562,"accession":"OP555634","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555634/2022-09-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0563/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-05"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C28104T","C28175T","G112246A","C125152T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C162012T"],"OPG044":["S5L"],"OPG131":["D103N"]},"labels":{"aa":"OPG044: S5L; OPG131: D103N"}}},{"name":"OP820450","node_attrs":{"div":558,"accession":"OP820450","author":{"author":"Barbian,H.,Green,S.,Kunstman,K.,Araujo Perez,F.,Bobrovska,S.,Hayden,M.,Moore,N.","value":"Barbian,H.,Green,S.,Kunstman,K.,Araujo Perez,F.,Bobrovska,S.,Hayden,M.,Moore,N."},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP820450/2022-09-10"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/Human/USA/IL-RIPHL-MPXV_10001/2022"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-10"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","G39090A","A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG057":["S369L"],"OPG153":["D385-"]},"labels":{"aa":"OPG057: S369L; OPG153: D385-"}}},{"name":"OP819948","node_attrs":{"div":563,"accession":"OP819948","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP819948/2022-10-15"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"VAC_INS_MPX_0952_C"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-15"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C33082T","C36405T","C40849T","G68103A","G117233A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C180361T"],"OPG049":["D24N"],"OPG055":["A227T"],"OPG060":["E112K"]},"labels":{"aa":"OPG049: D24N; OPG055: A227T; OPG060: E112K"}}},{"name":"OP693649","node_attrs":{"div":559,"accession":"OP693649","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"lineage":{"value":"B.1"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP693649/2022-07-29"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"ANT_INS_MPX_0039_L"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-29"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A2840-","T2841-","C2842-","G127058A","G136194A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","T196865-","A196866-","G196867-"],"OPG148":["R358K"],"OPG153":["H492Y"]},"labels":{"aa":"OPG148: R358K; OPG153: H492Y"}}},{"name":"OQ148466","node_attrs":{"div":562,"accession":"OQ148466","author":{"author":"Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"lineage":{"value":"B.1"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OQ148466/2022-09-13"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"LBMB-UTP_MP-009_TOL"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-13"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G57907A","C105991T","C114157T","C127215T","G175662A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG077":["S226L"],"OPG133":["E514K"],"OPG149":["S7L"],"OPG205":["E3K"]},"labels":{"aa":"OPG077: S226L; OPG133: E514K; OPG149: S7L; OPG205: E3K"}}},{"name":"OQ451900","node_attrs":{"div":558,"accession":"OQ451900","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ451900/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI715"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","G21655A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG037":["S260L"]},"labels":{"aa":"OPG037: S260L"}}},{"name":"OQ411312","node_attrs":{"div":558,"accession":"OQ411312","author":{"author":"Laubscher,F.,Chudzinsk,V.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinsk,V.,Schibler,M.,Kaiser,L.,Renzoni,A."},"lineage":{"value":"B.1"},"country":{"value":"Switzerland"},"strain_display":{"value":"Switzerland/OQ411312/2022-06-08"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMPXV-CH-38292866/2022"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-08"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C87764T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG109":["E562K"]},"labels":{"aa":"OPG109: E562K"}}},{"name":"OQ503839","node_attrs":{"div":561,"accession":"OQ503839","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ503839/2023-01-26"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00463/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-26"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C6310T","A39081T","C81194T","C102294T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T179244-","G190900A"],"OPG016":["R164K"],"OPG057":["I372N"],"OPG121":["Q169*"]},"labels":{"aa":"OPG016: R164K; OPG057: I372N; OPG121: Q169*"}}},{"name":"OQ503802","node_attrs":{"div":562,"accession":"OQ503802","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ503802/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00428/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G15683A","G74161A","C102758T","C104028T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G184416A"],"OPG094":["D128N"],"OPG122":["P111S"],"OPG123":["G348E"],"OPG210":["D1021N"]},"labels":{"aa":"OPG094: D128N; OPG122: P111S; OPG123: G348E; OPG210: D1021N"}}},{"name":"OR035717","node_attrs":{"div":560,"accession":"OR035717","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR035717/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_111"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G5444A","G113430A","T133099-","T133100-","G177160A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG015":["S238L"],"OPG205":["R502K"]},"labels":{"aa":"OPG015: S238L; OPG205: R502K"}}},{"name":"OQ918700","node_attrs":{"div":562,"accession":"OQ918700","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ918700/2023-02-20"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00489/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-20"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G66587A","G106113A","G143857A","C144237T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C189810T"],"OPG165":["S241L"]},"labels":{"aa":"OPG165: S241L"}}},{"name":"OQ918696","node_attrs":{"div":563,"accession":"OQ918696","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ918696/2023-03-11"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00485/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-11"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G30285A","G37487A","C71193T","G119839A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C161690T","C177865T","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T179244-"],"OPG047":["P304S"],"OPG137":["E80K"],"OPG188":["S32F"],"OPG205":["S737F"]},"labels":{"aa":"OPG047: P304S; OPG137: E80K; OPG188: S32F; OPG205: S737F"}}},{"name":"OQ672580","node_attrs":{"div":565,"accession":"OQ672580","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"B.1"},"country":{"value":"Taiwan"},"strain_display":{"value":"Taiwan/OQ672580/2023-03-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MPXV/human/Taiwan/110-093354/2023"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C39503G","G43620A","A44076G","G45563A","T69121C","T80764C","A130204G","A143123G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG057":["K231N"],"OPG064":["F608S"],"OPG087":["Y89H"],"OPG104":["N86D"],"OPG164":["T116A"]},"labels":{"aa":"OPG057: K231N; OPG064: F608S; OPG087: Y89H; OPG104: N86D; OPG164: T116A"}}},{"name":"OQ603470","node_attrs":{"div":558,"accession":"OQ603470","author":{"author":"Haw,M.,Kath,C.,Espinosa,A.,O'Neil,R.,Hacker,J.","value":"Haw,M.,Kath,C.,Espinosa,A.,O'Neil,R.,Hacker,J."},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ603470/2022-06-29"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000201/2023"},"institution":{"value":"CDPH, VRDL"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-29"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G125025A","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG145":["R360H"]},"labels":{"aa":"OPG145: R360H"}}},{"name":"OQ581849","node_attrs":{"div":559,"accession":"OQ581849","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"lineage":{"value":"B.1"},"country":{"value":"Spain"},"strain_display":{"value":"Spain/OQ581849/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0007b/2022"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A52777C","C150418T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T169409C","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG071":["Y554*"]},"labels":{"aa":"OPG071: Y554*"}}},{"name":"OR264422","node_attrs":{"div":559,"accession":"OR264422","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain_display":{"value":"Australia/OR264422/2022-07-13"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"},"strain":{"value":"46_B"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-13"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A41660-","A41661-","T41662-","T41663-","T41664-","G41665-","T41666-","T41667-","T41668-","T41669-","A41670-","C41671-","T41672-","C41673-","T41674-","A41675-","T41676-","C66963T","C118161T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG061":["R71-","V72-","K73-","Q74-","I75-"],"OPG136":["R476Q"]},"labels":{"aa":"OPG061: R71-, V72-, K73-, Q74-, I75-; OPG136: R476Q"}}},{"name":"OR264407","node_attrs":{"div":558,"accession":"OR264407","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain_display":{"value":"Australia/OR264407/2022-05-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"},"strain":{"value":"39_I"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-19"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","C21128T","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","T179244-","-196615A"],"OPG037":["E436K"]},"labels":{"aa":"OPG037: E436K"}}},{"name":"OR086957","node_attrs":{"div":557,"accession":"OR086957","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR086957/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_148/Belgium/2022"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196852-","G196853-","T196854-"]}}},{"name":"OX297403","node_attrs":{"div":558,"accession":"OX297403","lineage":{"value":"B.1"},"country":{"value":"Slovakia"},"strain_display":{"value":"Slovakia/OX297403/2022-08-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"RNA"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-09"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","G64522A","T133099-","T133100-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"]}}},{"name":"OX261748","node_attrs":{"div":557,"accession":"OX261748","lineage":{"value":"B.1"},"country":{"value":"Slovakia"},"strain_display":{"value":"Slovakia/OX261748/2022-07-13"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"RNA"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-13"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"]}}},{"name":"OR759186","node_attrs":{"div":561,"accession":"OR759186","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OR759186/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/Canada/ON-PHOL098/2022"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C77462T","C111164T","A143676G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C152385T"],"OPG098":["S188F"],"OPG130":["E247K"],"OPG165":["N54S"]},"labels":{"aa":"OPG098: S188F; OPG130: E247K; OPG165: N54S"}}},{"name":"OR759214","node_attrs":{"div":561,"accession":"OR759214","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OR759214/2022-07-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/Canada/ON-PHOL126/2022"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","C25172T","C67289T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G164327A","G164910A","A196614-"],"OPG040":["D103N"],"OPG085":["E415K"],"OPG189":["G332E"]},"labels":{"aa":"OPG040: D103N; OPG085: E415K; OPG189: G332E"}}},{"name":"OR759145","node_attrs":{"div":558,"accession":"OR759145","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OR759145/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/Canada/ON-PHOL054/2022"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C171732T"],"OPG199":["L249F"]},"labels":{"aa":"OPG199: L249F"}}},{"name":"OR499950","node_attrs":{"div":565,"accession":"OR499950","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR499950/2023-04-24"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00493/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-04-24"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C21494T","C69560T","C80874T","C86342T","C137855T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C182578T","C188161T","C189998T"],"OPG037":["D314N"],"OPG088":["V102M"],"OPG104":["S49N"],"OPG108":["D240N"],"OPG154":["E66K"],"OPG210":["S408L"]},"labels":{"aa":"OPG037: D314N; OPG088: V102M; OPG104: S49N; OPG108: D240N; OPG154: E66K; OPG210: S408L"}}},{"name":"OR464204","node_attrs":{"div":563,"accession":"OR464204","author":{"author":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y.","value":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y."},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR464204/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_OH0008"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","C30608T","G79318A","T84737C","G85774A","C118567T","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","G189329A","-196615A"],"OPG005":["R44K"],"OPG047":["R196Q"],"OPG107":["R88K"],"OPG136":["D341N"],"OPG153":["D385-"]},"labels":{"aa":"OPG005: R44K; OPG047: R196Q; OPG107: R88K; OPG136: D341N; OPG153: D385-"}}},{"name":"OR464192","node_attrs":{"div":563,"accession":"OR464192","author":{"author":"Gigante,C.,Pettit,D.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Deutsch-Feldman,M.,Li,Y.","value":"Gigante,C.,Pettit,D.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Deutsch-Feldman,M.,Li,Y."},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR464192/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_NC0016"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","C14091T","G16956A","G56721A","C94427T","G141759A","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","C184829T","A196614-"],"OPG025":["E393K"],"OPG114":["E81K"]},"labels":{"aa":"OPG025: E393K; OPG114: E81K"}}},{"name":"ON782022","node_attrs":{"div":557,"accession":"ON782022","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.,Sironen,T.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.,Sironen,T."},"lineage":{"value":"B.1"},"country":{"value":"Finland"},"strain_display":{"value":"Finland/ON782022/2022-05-31"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX-42/Finland/2022"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-31"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP382480","node_attrs":{"div":557,"accession":"OP382480","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"country":{"value":"France"},"strain_display":{"value":"France/OP382480/2022-07-04"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMPXV-IHU00003"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-04"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON755040","node_attrs":{"div":557,"accession":"ON755040","author":{"author":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O.","value":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O."},"lineage":{"value":"B.1"},"country":{"value":"France"},"strain_display":{"value":"France/ON755040/2022-05-20"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_IRBA22-14"},"institution":{"value":"IRBA, D.DNRBC/D.2MI/U.BACT"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-20"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264443","node_attrs":{"div":557,"accession":"OR264443","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain_display":{"value":"Australia/OR264443/2022-08-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"},"strain":{"value":"60_D"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-22"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C173173T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON694336","node_attrs":{"div":557,"accession":"ON694336","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/ON694336/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI024"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-","A192490-","A192491-","G192492-","T192493-","T192494-","A192495-","G192496-","T192497-","T192498-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"ON649879","node_attrs":{"div":557,"accession":"ON649879","author":{"author":"Israeli,O.,Guedj-Dana,Y.,Lazar,S.,Shifman,O.,Erez,N.,Weiss,S.,Paran,N.,Israely,T.,Schuster,O.,Zvi,A.,Beth-Din,A.,Cohen Gihon,I.","value":"Israeli,O.,Guedj-Dana,Y.,Lazar,S.,Shifman,O.,Erez,N.,Weiss,S.,Paran,N.,Israely,T.,Schuster,O.,Zvi,A.,Beth-Din,A.,Cohen Gihon,I."},"lineage":{"value":"B.1"},"country":{"value":"Israel"},"strain_display":{"value":"Israel/ON649879/2022-05-20"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MPXV_ISR001_2022"},"institution":{"value":"Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-20"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"ON631241","node_attrs":{"div":557,"accession":"ON631241","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"country":{"value":"Slovenia"},"strain_display":{"value":"Slovenia/ON631241/2022-05-24"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"2022/2 SLO"},"institution":{"value":"Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-24"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON563414","node_attrs":{"div":557,"accession":"ON563414","author":{"author":"Gigante,C.M.,Smole,S.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Brown,C.,Li,Y.","value":"Gigante,C.M.,Smole,S.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Brown,C.,Li,Y."},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/ON563414/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_MA001"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035674","node_attrs":{"div":557,"accession":"OR035674","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR035674/2022-06-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_68"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-30"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000091","node_attrs":{"div":558,"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","C144546T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"],"OPG166":["S50F"]},"labels":{"aa":"OPG166: S50F"}},"children":[{"name":"OP019275","node_attrs":{"div":560,"accession":"OP019275","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"country":{"value":"Austria"},"strain_display":{"value":"Austria/OP019275/2022-06-10"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMPXV/Austria/MUW1525179/2022"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-10"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","A107070C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G190319A","-196616A","-196617A"]}}},{"name":"OR473631","node_attrs":{"div":558,"accession":"OR473631","author":{"author":"Kwasiborski,A.,Hourdel,V.,Baliere,C.,Hoinard,D.,Grassin,Q.,Feher,M.,De La Porte Des Vaux,C.,Cresta,M.,Vanhomwegen,J.,Manuguerra,J.-C.,Batejat,C.,Caro,V.","value":"Kwasiborski,A.,Hourdel,V.,Baliere,C.,Hoinard,D.,Grassin,Q.,Feher,M.,De La Porte Des Vaux,C.,Cresta,M.,Vanhomwegen,J.,Manuguerra,J.-C.,Batejat,C.,Caro,V."},"lineage":{"value":"B.1"},"country":{"value":"France"},"strain_display":{"value":"France/OR473631/2022-06-03"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"CIBU-220031"},"institution":{"value":"Insitut Pasteur, Environment and Infectious Risks Unit"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-03"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A"]}}}]},{"name":"NODE_0000092","node_attrs":{"div":558,"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C4629T","G192581A"]}},"children":[{"name":"ON622713","node_attrs":{"div":558,"accession":"ON622713","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/ON622713/2022-05-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX/UZ_REGA_2/Belgium/2022"},"institution":{"value":"Microbiology, Immunology & Transplantation, KU Leuven, Rega Institute, Belgium"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-22"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP484690","node_attrs":{"div":563,"accession":"OP484690","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP484690/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI369"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A35026C","C75807T","C110546T","G141123A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C171794T"],"OPG096":["A74V"],"OPG161":["E8K"]},"labels":{"aa":"OPG096: A74V; OPG161: E8K"}}}]},{"name":"NODE_0000093","node_attrs":{"div":558,"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C130606T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}},"children":[{"name":"OP205113","node_attrs":{"div":560,"accession":"OP205113","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP205113/2022-06-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_UK_2022_9000150"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-16"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G89296T","G165465A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG109":["T51K"],"OPG190":["G115E"]},"labels":{"aa":"OPG109: T51K; OPG190: G115E"}}},{"name":"OQ627927","node_attrs":{"div":560,"accession":"OQ627927","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"lineage":{"value":"B.1"},"country":{"value":"Italy"},"strain_display":{"value":"Italy/OQ627927/2022-08-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"INMI-18982022"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-16"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C45203T","C88917T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226T","T179244-"]}}}]},{"name":"NODE_0000095","node_attrs":{"div":558,"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T133099-","T133100-","C176178T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196852-","G196853-","T196854-"],"OPG205":["H175Y"]},"labels":{"aa":"OPG205: H175Y"}},"children":[{"name":"OQ973326","node_attrs":{"div":561,"accession":"OQ973326","author":{"author":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L.","value":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L."},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OQ973326/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"case1_air"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-09-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","G2615-","A2616-","T2617-","A2618-","G2619-","A2620-","C2621-","A2622-","A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","T2653-","T2654-","T2655-","A2656-","C2657-","A2658-","C2659-","T2660-","T2661-","C111391T","C119654T","T133097-","T133098-","T133101-","T133102-","C152191T","A173314-","T173315-","A173316-","T173317-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A194549-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","A196613-","A196614-"],"OPG002":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-"],"OPG002_dup":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-"],"OPG130":["C171Y"],"OPG137":["S18L"]},"labels":{"aa":"OPG002: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-; OPG002_dup: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-; OPG130: C171Y; OPG137: S18L"}}},{"name":"OR087005","node_attrs":{"div":558,"accession":"OR087005","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR087005/2022-08-03"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_196/Belgium/2022"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-03"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000096","node_attrs":{"div":560,"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C34784T","C101418T","G109844A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG054":["D405N"],"OPG120":["D111N"]},"labels":{"aa":"OPG054: D405N; OPG120: D111N"}},"children":[{"name":"OR743497","node_attrs":{"div":565,"accession":"OR743497","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OR743497/2023-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1028"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-10-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C45528T","C84767T","G143777A","C170791T","G175934A"],"OPG064":["R124K"],"OPG165":["V88I"]},"labels":{"aa":"OPG064: R124K; OPG165: V88I"}}},{"name":"OR743495","node_attrs":{"div":561,"accession":"OR743495","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OR743495/2023-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1026"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G145312A"]}}}]},{"name":"NODE_0000097","node_attrs":{"div":561,"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","C117119T","C118453T","G137276A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177009A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG136":["E379K"],"OPG153":["S131F"],"OPG205":["E452K"]},"labels":{"aa":"OPG136: E379K; OPG153: S131F; OPG205: E452K"}},"children":[{"name":"OR499969","node_attrs":{"div":561,"accession":"OR499969","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR499969/2023-05-04"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00512/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-05-04"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179176A","-179177T","-179178A"]}}},{"name":"OR499971","node_attrs":{"div":563,"accession":"OR499971","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR499971/2023-05-04"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00514/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-05-04"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T39397C","T178873C","-179079A","-179080T","-179081A"],"OPG057":["N267D"]},"labels":{"aa":"OPG057: N267D"}}}]},{"name":"NODE_0000098","node_attrs":{"div":558,"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G169928A"],"OPG197":["D87N"]},"labels":{"aa":"OPG197: D87N"}},"children":[{"name":"ON853670","node_attrs":{"div":560,"accession":"ON853670","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/ON853670/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI090"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G58518A","G81977A"]}}},{"name":"NODE_0000099","node_attrs":{"div":560,"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G10118A","C15004T"],"OPG021":["E178K"]},"labels":{"aa":"OPG021: E178K"}},"children":[{"name":"ON983165","node_attrs":{"div":562,"accession":"ON983165","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/ON983165/2022-06-14"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/CAN/UN-NML-3686/2022"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-14"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G16819A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A163211-","A163212-","C163213-","T163214-","C180825T"],"OPG029":["S84L"],"OPG209":["S103F"]},"labels":{"aa":"OPG029: S84L; OPG209: S103F"}}},{"name":"ON751962","node_attrs":{"div":560,"accession":"ON751962","author":{"author":"Claro,I.M.,de Lima,E.L.,Romano,C.M.,Candido,D.S.,Lindoso,J.A.L.,Barra,L.A.C.,Borges,L.M.S.,Medeiros,L.A.,Tomishige,M.Y.S.,Ramundo,M.S.,Moutinho,T.,da Silva,A.J.D.,Rodrigues,C.C.M.,de Azevedo,L.C.F.,Villas-Boas,L.S.,da Silva,C.A.M.,Coletti,T.M.,O'Toole,A.,Quick,J.,Loman,N.,Rambaut,A.,Faria,N.R.,Figueiredo-Mello,C.,Sabino,E.C.","value":"Claro,I.M.,de Lima,E.L.,Romano,C.M.,Candido,D.S.,Lindoso,J.A.L.,Barra,L.A.C.,Borges,L.M.S.,Medeiros,L.A.,Tomishige,M.Y.S.,Ramundo,M.S.,Moutinho,T.,da Silva,A.J.D.,Rodrigues,C.C.M.,de Azevedo,L.C.F.,Villas-Boas,L.S.,da Silva,C.A.M.,Coletti,T.M.,O'Toole,A.,Quick,J.,Loman,N.,Rambaut,A.,Faria,N.R.,Figueiredo-Mello,C.,Sabino,E.C."},"lineage":{"value":"B.1"},"country":{"value":"Brazil"},"strain_display":{"value":"Brazil/ON751962/2022-06-07"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"Monkeypox/BR0001/2022"},"institution":{"value":"Imperial College London, School of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-07"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","G173575-","A173576-","G173577-","A173578-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]}]},{"name":"NODE_0000100","node_attrs":{"div":558,"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G190695A"],"OPG016":["E96K"]},"labels":{"aa":"OPG016: E96K"}},"children":[{"name":"OP743956","node_attrs":{"div":560,"accession":"OP743956","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP743956/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/OH-UW-083520/2022"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C11749-","C34432T","C67439T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG053":["E87K"],"OPG085":["D365N"]},"labels":{"aa":"OPG053: E87K; OPG085: D365N"}}},{"name":"NODE_0000101","node_attrs":{"div":559,"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C170573T"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}},"children":[{"name":"OP605567","node_attrs":{"div":561,"accession":"OP605567","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"country":{"value":"Slovenia"},"strain_display":{"value":"Slovenia/OP605567/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Slovenia-MPXV-25-2022"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C71938T","G73939A","T196886-","T196887-","T196888-"],"OPG092":["R337K"],"OPG094":["D54N"]},"labels":{"aa":"OPG092: R337K; OPG094: D54N"}}},{"name":"OQ451902","node_attrs":{"div":563,"accession":"OQ451902","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ451902/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI717"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","C3602T","C53342T","C124495T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159789A","G193608A"],"OPG003":["E336K"],"OPG003_dup":["E336K"],"OPG071":["R366K"]},"labels":{"aa":"OPG003: E336K; OPG003_dup: E336K; OPG071: R366K"}}}]}]},{"name":"NODE_0000102","node_attrs":{"div":559,"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C89166T","C112408T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG131":["L157F"]},"labels":{"aa":"OPG131: L157F"}},"children":[{"name":"OQ672570","node_attrs":{"div":559,"accession":"OQ672570","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OQ672570/2022-11-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"02112022_anal"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-02"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G47746-","G49680-","G49710-","G62109-","A62110-","T62111-","A62112-","A62113-","A62114-","G62115-","A62116-","G62117-","T62118-","C62119-","C62120-","T62121-","A62122-","T62123-","A62124-","T62125-","A62126-","T62127-","T62128-","T62129-","G62130-","A62131-","A62132-","A62133-","A62134-","T62135-","C62136-","G62137-","T62138-","T62139-","A62140-","C62141-","G62142-","G62143-","T62144-","T62145-","C62146-","G62147-","A62148-","T62149-","T62150-","A62151-","C62166-","A62167-","T62168-","T62169-","G62170-","T62171-","G62172-","A62173-","A62174-","T62175-","A62176-","T62177-","A62178-","T62179-","C62180-","A62181-","T62182-","T62183-","A62184-","G62185-","G62186-","A62187-","T62188-","T62189-","T62190-","A62191-","A62192-","C62193-","T62194-","C62195-","C62196-","T62197-","T62198-","G62199-","A62200-","C62201-","T62202-","A62203-","T62204-","C62205-","A62206-","T62207-","G62208-","G62209-","C62210-","G62211-","G62212-","T62213-","G62214-","C62215-","C62216-","A62217-","G62218-","A62219-","A62220-","A62221-","T62222-","T62223-","A62224-","C62225-","C62226-","A62227-","T62228-","C62229-","A62230-","A62231-","A62232-","A62233-","G62234-","C62235-","A62236-","T62237-","T62238-","A62239-","A62240-","T62241-","A62242-","C62243-","A62244-","G62245-","T62246-","T62247-","A62248-","T62249-","G62250-","C62251-","A62252-","G62253-","A62254-","T62255-","C62256-","G62257-","C62258-","A62259-","G62260-","T62261-","T62262-","A62263-","G62264-","A62265-","A62266-","C62267-","G62268-","G62269-","T62270-","T62271-","A62272-","T62273-","A62274-","G62275-","C62276-","A62277-","T62278-","C62279-","C62280-","A62281-","C62282-","C62283-","A62284-","T62285-","T62286-","T62287-","A62288-","T62289-","A62290-","T62291-","C62292-","T62293-","A62294-","A62295-","A62296-","A62297-","A62298-","T62299-","T62300-","A62301-","G62302-","A62303-","T62304-","C62305-","A62306-","A62307-","A62308-","G62309-","A62310-","A62311-","T62312-","A62313-","T62314-","G62315-","T62316-","G62317-","A62318-","C62319-","A62320-","A62321-","C62322-","G62323-","T62324-","C62325-","C62326-","T62327-","A62328-","G62329-","T62330-","T62331-","G62332-","T62333-","A62334-","T62335-","A62336-","C62337-","T62338-","G62339-","A62340-","G62341-","A62342-","A62343-","T62344-","T62345-","G62346-","A62347-","C62348-","G62349-","A62350-","A62351-","A62352-","C62353-","A62354-","A62355-","T62356-","G62357-","T62358-","T62359-","T62360-","C62361-","T62362-","T62363-","A62364-","C62365-","A62366-","T62367-","A62368-","T62369-","T62370-","T62371-","T62372-","T62373-","T62374-","T62375-","C62376-","T62377-","T62378-","A62379-","T62380-","T62381-","A62382-","G62383-","T62384-","A62385-","A62386-","C62387-","C62388-","G62389-","A62390-","C62391-","T62392-","T62393-","A62394-","A62395-","T62396-","A62397-","G62398-","T62399-","A62400-","G62401-","G62402-","A62403-","A62404-","C62405-","T62406-","G62407-","G62408-","A62409-","A62410-","A62411-","A62412-","C62413-","T62414-","A62415-","G62416-","A62417-","C62418-","T62419-","T62420-","G62421-","A62422-","T62423-","T62424-","A62425-","T62426-","T62427-","C62428-","T62429-","A62430-","T62431-","A62432-","A62433-","G62434-","T62435-","A62436-","T62437-","A62438-","G62439-","A62440-","T62441-","A62442-","C62443-","C62444-","C62445-","T62446-","T62447-","C62448-","C62449-","A62450-","A62451-","A62452-","T62453-","A62454-","A62455-","T62456-","G62457-","T62458-","T62459-","C62460-","T62461-","C62462-","T62463-","T62464-","T62465-","G62466-","A62467-","T62468-","A62469-","A62470-","A62471-","A62472-","G62473-","T62474-","T62475-","C62476-","C62477-","A62478-","G62479-","A62480-","A62481-","A62482-","A62483-","T62484-","G62485-","T62486-","A62487-","G62488-","A62489-","A62490-","T62491-","T62492-","T62493-","T62494-","T62495-","T62496-","A62497-","A62498-","A62499-","A62500-","A62501-","G62502-","T62503-","T62504-","A62505-","T62506-","C62507-","T62508-","T62509-","T62510-","T62511-","G62512-","C62513-","T62514-","A62515-","T62516-","T62517-","A62518-","C62519-","T62520-","A62521-","A62522-","T62523-","A62524-","T62525-","C62526-","G62527-","T62528-","G62529-","G62530-","T62531-","T62532-","A62533-","G62534-","A62535-","C62536-","G62537-","C62538-","T62539-","T62540-","A62541-","T62542-","T62543-","A62544-","T62545-","T62546-","A62547-","A62548-","T62549-","A62550-","T62551-","G62552-","A62553-","G62554-","T62555-","G62556-","A62557-","T62558-","G62559-","A62560-","A62561-","A62562-","T62563-","C62564-","C62565-","A62566-","C62567-","A62568-","C62569-","C62570-","G62571-","C62572-","T62573-","T62574-","C62575-","T62576-","A62577-","G62578-","A62579-","T62580-","A62581-","T62582-","C62583-","G62584-","C62585-","T62586-","T62587-","T62588-","T62589-","A62590-","T62591-","T62592-","T62593-","C62594-","C62595-","A62596-","C62597-","A62598-","T62599-","T62600-","A62601-","G62602-","A62603-","T62604-","G62605-","G62606-","T62607-","A62608-","A62609-","A62610-","T62611-","C62612-","C62613-","A62614-","A62615-","T62616-","A62617-","G62618-","T62619-","G62620-","A62621-","A62622-","A62623-","C62624-","T62625-","A62626-","T62627-","C62628-","T62629-","T62630-","A62703-","T62704-","A62705-","A62706-","A62707-","C62708-","A62709-","A62710-","T62711-","T62712-","T62713-","C62714-","A62715-","C62716-","A62717-","A62718-","A62719-","T62720-","G62721-","G62722-","A62723-","T62724-","G62725-","T62726-","T62727-","A62728-","A62729-","T62730-","G62731-","T62732-","A62733-","T62734-","T62735-","A62736-","G62737-","T62738-","A62739-","G62740-","G62741-","A62742-","A62743-","A62744-","T62745-","T62746-","T62747-","T62748-","T62749-","T62750-","G62751-","A62752-","C62753-","G62754-","C62755-","T62756-","A62757-","G62758-","T62759-","G62760-","G62761-","A62762-","A62763-","T62764-","T62765-","G62766-","A62767-","A62768-","G62769-","A62770-","T62771-","T62772-","C62773-","T62774-","A62775-","A62776-","T62777-","G62778-","G62779-","A62780-","T62781-","G62782-","A62783-","T62784-","G62785-","T62786-","T62787-","C62788-","T62789-","A62790-","C62791-","C62792-","T62793-","A62794-","T62795-","T62796-","T62797-","C62798-","A62799-","T62800-","C62801-","C62802-","G62803-","A62804-","T62805-","A62806-","A62807-","C62808-","A62809-","T62810-","G62811-","T62812-","T62813-","A62814-","A62815-","T62816-","T62817-","T62818-","C62819-","C62820-","A62821-","A62822-","T62823-","A62824-","C62825-","C62826-","A62827-","A62828-","C62829-","G62830-","G62831-","T62832-","T62833-","T62834-","T62835-","A62836-","A62837-","T62838-","A62839-","T62840-","T62841-","T62842-","C62843-","G62844-","A62845-","T62846-","G62847-","A62848-","T62849-","A62850-","T62851-","A62852-","C62853-","G62854-","G62855-","T62856-","A62857-","G62858-","T62859-","C62860-","T62861-","C62862-","T62863-","C62864-","T62865-","T62866-","T62867-","C62868-","G62869-","G62870-","A62871-","C62872-","T62873-","T62874-","A62875-","T62876-","A62877-","T62878-","A62879-","G62880-","C62881-","T62882-","T62883-","A62884-","T62885-","T62886-","C62887-","C62888-","A62889-","C62890-","A62891-","A62892-","T62893-","A62894-","C62895-","G62896-","A62897-","G62898-","T62899-","C62900-","A62901-","T62902-","T62903-","A62904-","T62905-","A62906-","T62907-","A62908-","C62909-","T62910-","C62911-","C62912-","A62913-","A62914-","A62915-","A62916-","A62917-","A62918-","C62919-","A62920-","A62921-","A62922-","A62923-","T62924-","A62925-","A62926-","C62927-","T62928-","A62929-","G62930-","T62931-","A62932-","T62933-","A62934-","A62935-","A62936-","A62937-","T62938-","C62939-","T62940-","G62941-","T62942-","A62943-","T62944-","C62945-","G62946-","A62947-","A62948-","T62949-","G62950-","G62951-","G62952-","A62953-","A62954-","A62955-","A62956-","A62957-","C62958-","G62959-","A62960-","A62961-","A62962-","T62963-","T62964-","A62965-","T62966-","C62967-","G62968-","A62969-","T62970-","A62971-","T62972-","A62973-","G62974-","G62975-","T62976-","A62977-","T62978-","A62979-","G62980-","A62981-","A62982-","T62983-","C62984-","C62985-","G62986-","G62987-","A62988-","A62989-","C62990-","A62991-","T62992-","T62993-","G62994-","A62995-","A62996-","C62997-","G62998-","T62999-","A63000-","T63001-","T63002-","A63003-","A63004-","T63005-","A63006-","C63007-","T63008-","T63009-","A63010-","A63011-","T63012-","T63013-","C63014-","T63015-","T63016-","T63017-","T63018-","T63019-","C63020-","A63021-","G63022-","T63023-","G63024-","G63025-","T63026-","A63027-","A63028-","G63029-","A63030-","A63031-","C63032-","C63033-","G63034-","A63035-","T63036-","A63037-","G63038-","G63039-","T63040-","T63041-","A63042-","T63043-","T63044-","G63045-","A63046-","C63047-","A63048-","T63049-","T63050-","G63051-","T63052-","A63053-","T63054-","G63055-","G63056-","T63057-","T63058-","T63059-","T63060-","A63061-","A63062-","A63063-","T63064-","A63065-","T63066-","T63067-","C63068-","T63069-","A63070-","T63071-","A63072-","A63073-","C63074-","T63075-","T63076-","G63077-","A63078-","G63079-","A63080-","C63081-","T63082-","T63083-","G63084-","A63085-","T63086-","A63087-","G63088-","A63089-","T63090-","A63091-","T63092-","T63093-","A63094-","A63095-","T63096-","G63097-","A63098-","C63099-","G63100-","A63101-","A63102-","T63103-","T63104-","G63105-","A63106-","A63107-","A63108-","A63109-","T63110-","T63111-","A63112-","T63113-","T63114-","T63115-","T63116-","T63117-","A63118-","T63119-","C63120-","A63121-","C63122-","C63123-","A63124-","C63125-","G63126-","T63127-","G63128-","T63129-","G63130-","T63131-","T63132-","T63133-","C63134-","A63135-","G63136-","G63137-","A63138-","T63139-","C63140-","A63141-","T63142-","C63143-","G63144-","T63145-","C63146-","G63147-","A63148-","C63149-","G63150-","C63151-","C63152-","A63153-","G63154-","T63155-","T63156-","A63157-","A63158-","C63159-","C63160-","A63161-","A63162-","C63163-","C63164-","G63165-","A63166-","A63167-","T63168-","G63169-","G63170-","A63171-","G63172-","T63173-","A63174-","A63175-","A63176-","A63177-","T63178-","A63179-","A63180-","A63181-","T63182-","A63183-","T63184-","C63185-","A63186-","T63187-","T63188-","A63189-","A63190-","T63191-","A63192-","T63193-","A63194-","T63195-","G63196-","C63197-","T63198-","C63199-","T63200-","A63201-","G63202-","A63203-","T63204-","A63205-","T63206-","T63207-","A63208-","G63209-","T63210-","A63211-","T63212-","T63213-","T63214-","T63215-","T63216-","A63217-","T63218-","T63219-","A63220-","A63221-","T63222-","C63223-","C63224-","T63225-","T63226-","T63227-","G63228-","A63229-","T63230-","T63231-","A63232-","T63233-","C63234-","A63235-","T63236-","C63237-","T63238-","T63239-","C63240-","T63241-","C63242-","G63243-","T63244-","A63245-","C63246-","G63247-","C63248-","G63249-","A63250-","A63251-","T63252-","G63253-","A63254-","T63255-","T63256-","C63257-","C63258-","A63259-","T63260-","G63261-","A63262-","T63263-","C63264-","A63265-","A63266-","G63267-","A63268-","G63269-","T63270-","G63271-","A63272-","T63273-","T63274-","T63275-","G63276-","A63277-","G63278-","A63279-","A63280-","C63281-","A63282-","T63283-","C63284-","C63285-","T63286-","C63287-","C63288-","G63289-","G63290-","A63291-","G63292-","T63293-","A63294-","T63295-","T63296-","A63297-","A63298-","T63299-","G63300-","G63301-","G63302-","T63303-","T63304-","T63305-","A63306-","G63307-","T63308-","A63309-","A63310-","A63311-","C63312-","A63313-","G63314-","T63315-","C63316-","C63317-","A63318-","T63319-","C63320-","G63321-","T63322-","T63323-","G63324-","C63325-","A63326-","A63327-","T63328-","A63329-","A63330-","T63331-","A63332-","A63333-","A63334-","A63335-","G63336-","T63337-","T63338-","G63339-","T63340-","C63341-","C63342-","A63343-","A63344-","G63345-","T63346-","T63347-","A63348-","A63349-","A63350-","G63351-","G63352-","A63353-","T63354-","A63355-","T63356-","T63357-","A63358-","T63359-","G63360-","C63361-","A63362-","T63363-","T63364-","C63365-","G63366-","T63367-","T63368-","T63369-","A63370-","A63371-","A63372-","G63373-","A63374-","T63375-","A63376-","T63377-","C63378-","A63379-","C63380-","C63381-","T63382-","C63383-","A63384-","T63385-","C63386-","T63387-","A63388-","A63389-","C63390-","G63391-","G63392-","A63393-","G63394-","A63395-","C63396-","A63397-","A63398-","T63399-","T63400-","T63401-","T63402-","T63403-","T63404-","G63405-","G63406-","T63407-","A63408-","G63409-","G63410-","T63411-","T63412-","T63413-","T63414-","A63415-","G63416-","A63417-","G63418-","A63419-","C63420-","T63421-","T63422-","T63423-","G63424-","A63425-","A63426-","G63427-","C63428-","T63429-","A63430-","C63431-","T63432-","T63433-","G63434-","T63435-","T63436-","T63437-","A63438-","A63439-","C63440-","A63441-","A63442-","A63443-","G63444-","T63445-","T63446-","A63447-","T63448-","T63449-","C63450-","A63451-","T63452-","C63453-","G63454-","T63455-","C63456-","G63457-","T63458-","C63459-","T63460-","A63461-","C63462-","T63463-","A63464-","T63465-","T63466-","C63467-","T63468-","A63469-","T63470-","T63471-","T63472-","A63473-","A63474-","T63475-","T63476-","T63477-","T63478-","G63479-","T63480-","A63481-","G63482-","T63483-","T63484-","A63485-","A63486-","T63487-","T63488-","T63489-","A63490-","T63491-","C63492-","A63493-","C63494-","A63495-","T63496-","A63497-","T63498-","C63499-","A63500-","C63501-","A63502-","T63503-","T63504-"],"OPG068":["D494-"],"OPG081":["N46-","R47-","T48-","V49-","T50-","I51-","F52-","K53-","Y54-","I55-","G56-","L57-","F58-","I59-"]},"labels":{"aa":"OPG068: D494-; OPG081: N46-, R47-, T48-, V49-, T50-, I51-, F52-, K53-, Y54-, I55-, G56-, L57-, F58-, I59-"}}},{"name":"NODE_0000103","node_attrs":{"div":560,"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","G187391A","A194549-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-"],"OPG002":["R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-","C47-"],"OPG002_dup":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-"]},"labels":{"aa":"OPG002: R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-, C47-; OPG002_dup: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-"}},"children":[{"name":"OQ672572","node_attrs":{"div":560,"accession":"OQ672572","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OQ672572/2023-01-26"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"26012023_anal"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-26"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OQ672576","node_attrs":{"div":562,"accession":"OQ672576","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OQ672576/2023-02-08"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"08022023_anal"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-08"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T39397C","T70389G"],"OPG057":["N267D"],"OPG089":["M175R"]},"labels":{"aa":"OPG057: N267D; OPG089: M175R"}}}]}]},{"name":"NODE_0000104","node_attrs":{"div":564,"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C18441T","G22415A","G70002A","C132698T","G143951A","C148604T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G154188A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG031":["E130K"],"OPG089":["R46K"],"OPG165":["D146N"],"OPG174":["M264I"]},"labels":{"aa":"OPG031: E130K; OPG089: R46K; OPG165: D146N; OPG174: M264I"}},"children":[{"name":"OR643702","node_attrs":{"div":565,"accession":"OR643702","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR643702/2023-08-08"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00560/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-08-08"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C14823A"],"OPG025":["D149Y"]},"labels":{"aa":"OPG025: D149Y"}}},{"name":"OR499994","node_attrs":{"div":564,"accession":"OR499994","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR499994/2023-07-21"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00538/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-07-21"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OR499988","node_attrs":{"div":565,"accession":"OR499988","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR499988/2023-06-24"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00532/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-06-24"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C112565T","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG132":["E326K"]},"labels":{"aa":"OPG132: E326K"}}}]},{"name":"NODE_0000105","node_attrs":{"div":561,"lineage":{"value":"B.1.16"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C9389T","C30154T","G161797A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","A185557C"],"OPG188":["E68K"],"OPG210":["K1401T"]},"labels":{"aa":"OPG188: E68K; OPG210: K1401T","clade":"B.1.16"}},"children":[{"name":"OP459211","node_attrs":{"div":562,"accession":"OP459211","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.16"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP459211/2022-08-29"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"ANT-LDSP-ANT-MPX-23596-O"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-29"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G170076A"]}}},{"name":"OP642383","node_attrs":{"div":562,"accession":"OP642383","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.16"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP642383/2022-09-09"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"ANT-LDSP-ANT-MPX-24909-C"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-09"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G6863A","C132608T"]}}},{"name":"OP693647","node_attrs":{"div":561,"accession":"OP693647","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"lineage":{"value":"B.1.16"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP693647/2022-08-08"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"DC_INS_MPX_0082_L"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-08"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A1701-","C1702-","T1703-","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-","T196852-","G196853-","T196854-"]}}},{"name":"NODE_0000106","node_attrs":{"div":562,"lineage":{"value":"B.1.16"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G148403A","-180517A","-180518A","-180519T","-180520G","-180521A","-180522C","-180523G","-180524A","-180525T","-180526A","-180527T","-180528A","-180529C","-180530G","-180531G","-180532A","-180533T","-180534T"]}},"children":[{"name":"OP819955","node_attrs":{"div":570,"accession":"OP819955","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.16"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP819955/2022-10-13"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"VAC_INS_MPX_0962_C"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-13"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C53865T","C57810T","G69840A","C117200T","C124379T","G161421A","C178546T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188775T"],"OPG071":["D192N"],"OPG145":["H145Y"],"OPG187":["R267K"]},"labels":{"aa":"OPG071: D192N; OPG145: H145Y; OPG187: R267K"}}},{"name":"OQ696095","node_attrs":{"div":564,"accession":"OQ696095","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.16"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OQ696095/2022-11-08"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"ANT-LDSP-ANT-MPX-30094O"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-08"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","G104597A","C116175T","G150568A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"]}}}]}]},{"name":"NODE_0000107","node_attrs":{"div":558,"lineage":{"value":"B.1.9"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","G181367A","A196614-"]},"labels":{"clade":"B.1.9"}},"children":[{"name":"ON843175","node_attrs":{"div":558,"accession":"ON843175","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.9"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/ON843175/2022-05-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0043/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-30"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP693652","node_attrs":{"div":559,"accession":"OP693652","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"lineage":{"value":"B.1.9"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP693652/2022-08-16"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"DC_INS_MPX_0718_L"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-16"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-606T","G134122T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP687938","node_attrs":{"div":561,"accession":"OP687938","author":{"author":"Gigante,C.M.,Acheampong,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Morrison,S.S.,Seabolt,M.H.,Weigand,M.R.,Knipe,K.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,McDermott,D.,Li,Y.","value":"Gigante,C.M.,Acheampong,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Morrison,S.S.,Seabolt,M.H.,Weigand,M.R.,Knipe,K.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,McDermott,D.,Li,Y."},"lineage":{"value":"B.1.9"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP687938/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_NJ0005"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G61329A","C101868T","C103427T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG121":["P27S"]},"labels":{"aa":"OPG121: P27S"}}},{"name":"NODE_0000108","node_attrs":{"div":559,"lineage":{"value":"B.1.9"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","G176823A"],"OPG205":["E390K"]},"labels":{"aa":"OPG205: E390K"}},"children":[{"name":"ON880538","node_attrs":{"div":560,"accession":"ON880538","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.9"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/ON880538/2022-06-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/CAN/UN-NML-3336/2022"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-11326A","-11327T","-11328C","-11329T","-11330A","-11331C","-11332G","-11333A","-11334T","-11335A","-11336T","-11337T","-11338A","-11339G","-11340A","-11341T","-11342A","-11343C","-11344T","-11345T","-11346C","-11347A","-11348C","-11349T","-11350C","-11351A","-11352A","-11353T","-11354G","-11355A","-11356A","-11357T","-11358C","-11359A","-11360A","-11361T","-11362C","-11363A","-11364C","-11365A","-11366C","-11367A","-11368A","-11369T","-11370C","-11371T","-11372A","-11373A","-11374T","-11375G","-11376T","-11377A","-11378G","-11379G","-11380T","-11381T","-11382T","-11383A","-11384T","-11385G","-11386A","-11387C","-11388A","-11389T","-11390A","-11391A","-11392T","-11393A","-11394G","-11395C","-11396A","-11397T","-11398T","-11399T","-11400T","-11401C","-11402A","-11403G","-11404C","-11405A","-11406G","-11407T","-11408T","-11409C","-11410A","-11411A","-11412T","-11413G","-11414T","-11415T","-11416T","-11417C","-11418T","-11419A","-11420G","-11421A","-11422T","-11423T","-11424C","-11425G","-11426T","-11427T","-11428G","-11429A","-11430T","-11431G","-11432G","-11433C","-11434A","-11435A","-11436T","-11437G","-11438G","-11439T","-11440T","-11441A","-11442T","-11443A","-11444C","-11445A","-11446T","-11447G","-11448T","-11449A","-11450T","-11451A","-11452T","-11453C","-11454C","-11455G","-11456T","-11457T","-11458A","-11459T","-11460T","-11461T","-11462G","-11463A","-11464T","-11465C","-11466T","-11467A","-11468A","-11469T","-11470G","-11471T","-11472T","-11473G","-11474A","-11475C","-11476A","-11477T","-11478C","-11479T","-11480G","-11481A","-11482A","-11483C","-11484C","-11485G","-11486G","-11487A","-11488T","-11489T","-11490C","-11491T","-11492A","-11493G","-11494C","-11495A","-11496G","-11497T","-11498A","-11499A","-11500A","-11501G","-11502A","-11503T","-11504A","-11505C","-11506T","-11507A","-11508G","-11509A","-11510G","-11511A","-11512T","-11513T","-11514G","-11515T","-11516T","-11517T","-11518A","-11519T","-11520T","-11521A","-11522T","-11523A","-11524T","-11525C","-11526T","-11527A","-11528A","-11529C","-11530A","-11531G","-11532C","-11533C","-11534T","-11535T","-11536G","-11537T","-11538G","-11539A","-11540A","-11541G","-11542A","-11543A","-11544G","-11545T","-11546G","-11547T","-11548T","-11549T","-11550C","-11551T","-11552C","-11553C","-11554T","-11555C","-11556G","-11557T","-11558T","-11559T","-11560G","-11561T","-11562C","-11563A","-11564A","-11565T","-11566C","-11567A","-11568T","-11569G","-11570T","-11571T","-11572A","-11573A","-11574T","-11575G","-11576T","-11577C","-11578T","-11579T","-11580T","-11581A","-11582A","-11583G","-11584A","-11585T","-11586A","-11587A","-11588G","-11589G","-11590T","-11591A","-11592G","-11593A","-11594C","-11595A","-11596A","-11597A","-11598T","-11599G","-11600T","-11601T","-11602T","-11603A","-11604T","-11605A","-11606G","-11607T","-11608A","-11609C","-11610T","-11611A","-11612A","-11613G","-11614A","-11615A","-11616T","-11617T","-11618G","-11619G","-11620G","-11621C","-11622A","-11623A","-11624A","-11625C","-11626A","-11627T","-11628A","-11629A","-11630G","-11631A","-11632C","-11633A","-11634T","-11635G","-11636T","-11637C","-11638A","-11639C","-11640A","-11641A","-11642A","-11643G","-11644A","-11645C","-11646C","-11647C","-11648T","-11649T","-11650T","-11651T","-11652T","-11653G","-11654T","-11655A","-11656T","-11657G","-11658T","-11659A","-11660T","-11661A","-11662A","-11663G","-11664T","-11665G","-11666T","-11667A","-11668G","-11669A","-11670A","-11671A","-11672T","-11673T","-11674A","-11675T","-11676A","-11677A","-11678C","-11679A","-11680T","-11681C","-11682C","-11683A","-11684T","-11685A","-11686G","-11687T","-11688T","-11689G","-11690G","-11691A","-11692T","-11693T","-11694C","-11695A","-11696C","-11697A","-11698T","-11699A","-11700G","-11701G","-11702T","-11703G","-11704T","-11705C","-11706C","-11707A","-11708A","-11709T","-11710C","-11711G","-11712G","-11713G","-11714A","-11715T","-11716C","-11717T","-11718C","-11719T","-11720C","-11721C","-11722A","-11723T","-11724C","-11725A","-11726T","-11727C","-11728G","-11729A","-11730G","-11731A","-11732T","-11733G","-11734A","-11735T","-11736T","-11737G","-11738A","-11739C","-11740G","-11741G","-11742C","-11743A","-11744T","-11745C","-11746T","-11747C","-11748C","-11749C","-11750C","-11751C","-11752T","-11753T","-11754C","-11755C","-11756T","-11757T","-11758T","-11759T","-11760T","-11761T","-11762A","-11763G","-11764T","-11765A","-11766G","-11767A","-11768T","-11769A","-11770T","-11771T","-11772T","-11773C","-11774A","-11775T","-11776C","-11777G","-11778T","-11779G","-11780T","-11781A","-11782A","-11783G","-11784A","-11785A","-11786T","-11787C","-11788A","-11789A","-11790T","-11791A","-11792T","-11793T","-11794A","-11795A","-11796T","-11797A","-11798T","-11799T","-11800T","-11801C","-11802T","-11803A","-11804A","-11805A","-11806G","-11807T","-11808A","-11809T","-11810C","-11811T","-11812G","-11813T","-11814G","-11815T","-11816A","-11817T","-11818A","-11819G","-11820C","-11821C","-11822T","-11823C","-11824T","-11825T","-11826T","-11827A","-11828T","-11829T","-11830T","-11831A","-11832C","-11833C","-11834A","-11835C","-11836A","-11837G","-11838C","-11839T","-11840C","-11841C","-11842A","-11843T","-11844A","-11845T","-11846T","-11847C","-11848C","-11849A","-11850A","-11851C","-11852A","-11853T","-11854G","-11855C","-11856A","-11857T","-11858T","-11859C","-11860C","-11861A","-11862C","-11863T","-11864A","-11865G","-11866A","-11867G","-11868G","-11869G","-11870A","-11871T","-11872A","-11873T","-11874C","-11875G","-11876A","-11877T","-11878A","-11879T","-11880C","-11881G","-11882C","-11883C","-11884G","-11885A","-11886A","-11887T","-11888G","-11889T","-11890C","-11891A","-11892T","-11893A","-11894T","-11895A","-11896C","-11897T","-11898C","-11899A","-11900A","-11901T","-11902T","-11903A","-11904G","-11905T","-11906A","-11907T","-11908A","-11909T","-11910G","-11911T","-11912T","-11913G","-11914G","-11915A","-11916G","-11917G","-11918A","-11919C","-11920A","-11921T","-11922C","-11923C","-11924G","-11925A","-11926G","-11927T","-11928T","-11929C","-11930A","-11931T","-11932T","-11933G","-11934T","-11935T","-11936T","-11937T","-11938C","-11939A","-11940A","-11941T","-11942A","-11943T","-11944C","-11945A","-11946A","-11947A","-11948G","-11949A","-11950G","-11951A","-11952T","-11953G","-11954G","-11955T","-11956T","-11957T","-11958C","-11959C","-11960T","-11961T","-11962A","-11963T","-11964C","-11965A","-11966T","-11967T","-11968T","-11969C","-11970T","-11971C","-11972C","-11973A","-11974T","-11975A","-11976G","-11977T","-11978G","-11979G","-11980T","-11981A","-11982C","-11983A","-11984A","-11985T","-11986A","-11987C","-11988T","-11989A","-11990C","-11991A","-11992C","-11993A","-11994T","-11995T","-11996A","-11997T","-11998T","-11999C","-12000C","-12001G","-12002T","-12003A","-12004C","-12005G","-12006G","-12007C","-12008T","-12009T","-12010T","-12011C","-12012C","-12013A","-12014T","-12015T","-12016C","-12017T","-12018C","-12019C","-12020A","-12021A","-12022A","-12023A","-12024A","-12025C","-12026A","-12027A","-12028T","-12029T","-12030T","-12031T","-12032A","-12033C","-12034C","-12035A","-12036A","-12037A","-12038T","-12039C","-12040T","-12041A","-12042A","-12043A","-12044T","-12045C","-12046T","-12047A","-12048C","-12049A","-12050T","-12051C","-12052T","-12053T","-12054T","-12055A","-12056T","-12057T","-12058G","-12059T","-12060A","-12061T","-12062C","-12063T","-12064A","-12065T","-12066A","-12067A","-12068T","-12069C","-12070A","-12071C","-12072T","-12073A","-12074T","-12075T","-12076T","-12077A","-12078G","-12079A","-12080T","-12081A","-12082A","-12083T","-12084C","-12085A","-12086G","-12087C","-12088C","-12089A","-12090T","-12091A","-12092A","-12093T","-12094T","-12095C","-12096C","-12097T","-12098C","-12099G","-12100A","-12101G","-12102T","-12103G","-12104C","-12105A","-12106A","-12107C","-12108A","-12109T","-12110G","-12111T","-12112T","-12113A","-12114G","-12115A","-12116T","-12117C","-12118G","-12119T","-12120C","-12121T","-12122A","-12123T","-12124A","-12125T","-12126A","-12127T","-12128G","-12129A","-12130A","-12131T","-12132A","-12133A","-12134G","-12135C","-12136C","-12137G","-12138T","-12139G","-12140T","-12141T","-12142A","-12143T","-12144C","-12145T","-12146A","-12147T","-12148T","-12149C","-12150C","-12151T","-12152T","-12153T","-12154C","-12155A","-12156T","-12157T","-12158A","-12159A","-12160C","-12161A","-12162A","-12163T","-12164T","-12165T","-12166A","-12167A","-12168C","-12169G","-12170A","-12171T","-12172G","-12173T","-12174C","-12175T","-12176A","-12177T","-12178A","-12179T","-12180C","-12181T","-12182A","-12183T","-12184A","-12185T","-12186G","-12187A","-12188G","-12189A","-12190T","-12191G","-12192A","-12193C","-12194T","-12195T","-12196A","-12197A","-12198T","-12199A","-12200T","-12201A","-12202A","-12203T","-12204A","-12205T","-12206T","-12207G","-12208A","-12209A","-12210G","-12211A","-12212G","-12213C","-12214T","-12215G","-12216T","-12217A","-12218C","-12219A","-12220A","-12221T","-12222A","-12223G","-12224T","-12225T","-12226T","-12227T","-12228T","-12229A","-12230T","-12231C","-12232T","-12233A","-12234T","-12235A","-12236G","-12237A","-12238A","C32627T"]}}},{"name":"ON585037","node_attrs":{"div":560,"accession":"ON585037","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.9"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/ON585037/2022-05-15"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0005/2022"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-15"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-606T","G82853A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A188351-","-196614A"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-"}}},{"name":"NODE_0000109","node_attrs":{"div":560,"lineage":{"value":"B.1.9"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C34432T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG053":["E87K"]},"labels":{"aa":"OPG053: E87K"}},"children":[{"name":"OP324533","node_attrs":{"div":560,"accession":"OP324533","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.9"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP324533/2022-06-24"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0223/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-24"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-"}}},{"name":"NODE_0000110","node_attrs":{"div":561,"lineage":{"value":"B.1.9"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-11326A","-11327T","-11328C","-11329T","-11330A","-11331C","-11332G","-11333A","-11334T","-11335A","-11336T","-11337T","-11338A","-11339G","-11340A","-11341T","-11342A","-11343C","-11344T","-11345T","-11346C","-11347A","-11348C","-11349T","-11350C","-11351A","-11352A","-11353T","-11354G","-11355A","-11356A","-11357T","-11358C","-11359A","-11360A","-11361T","-11362C","-11363A","-11364C","-11365A","-11366C","-11367A","-11368A","-11369T","-11370C","-11371T","-11372A","-11373A","-11374T","-11375G","-11376T","-11377A","-11378G","-11379G","-11380T","-11381T","-11382T","-11383A","-11384T","-11385G","-11386A","-11387C","-11388A","-11389T","-11390A","-11391A","-11392T","-11393A","-11394G","-11395C","-11396A","-11397T","-11398T","-11399T","-11400T","-11401C","-11402A","-11403G","-11404C","-11405A","-11406G","-11407T","-11408T","-11409C","-11410A","-11411A","-11412T","-11413G","-11414T","-11415T","-11416T","-11417C","-11418T","-11419A","-11420G","-11421A","-11422T","-11423T","-11424C","-11425G","-11426T","-11427T","-11428G","-11429A","-11430T","-11431G","-11432G","-11433C","-11434A","-11435A","-11436T","-11437G","-11438G","-11439T","-11440T","-11441A","-11442T","-11443A","-11444C","-11445A","-11446T","-11447G","-11448T","-11449A","-11450T","-11451A","-11452T","-11453C","-11454C","-11455G","-11456T","-11457T","-11458A","-11459T","-11460T","-11461T","-11462G","-11463A","-11464T","-11465C","-11466T","-11467A","-11468A","-11469T","-11470G","-11471T","-11472T","-11473G","-11474A","-11475C","-11476A","-11477T","-11478C","-11479T","-11480G","-11481A","-11482A","-11483C","-11484C","-11485G","-11486G","-11487A","-11488T","-11489T","-11490C","-11491T","-11492A","-11493G","-11494C","-11495A","-11496G","-11497T","-11498A","-11499A","-11500A","-11501G","-11502A","-11503T","-11504A","-11505C","-11506T","-11507A","-11508G","-11509A","-11510G","-11511A","-11512T","-11513T","-11514G","-11515T","-11516T","-11517T","-11518A","-11519T","-11520T","-11521A","-11522T","-11523A","-11524T","-11525C","-11526T","-11527A","-11528A","-11529C","-11530A","-11531G","-11532C","-11533C","-11534T","-11535T","-11536G","-11537T","-11538G","-11539A","-11540A","-11541G","-11542A","-11543A","-11544G","-11545T","-11546G","-11547T","-11548T","-11549T","-11550C","-11551T","-11552C","-11553C","-11554T","-11555C","-11556G","-11557T","-11558T","-11559T","-11560G","-11561T","-11562C","-11563A","-11564A","-11565T","-11566C","-11567A","-11568T","-11569G","-11570T","-11571T","-11572A","-11573A","-11574T","-11575G","-11576T","-11577C","-11578T","-11579T","-11580T","-11581A","-11582A","-11583G","-11584A","-11585T","-11586A","-11587A","-11588G","-11589G","-11590T","-11591A","-11592G","-11593A","-11594C","-11595A","-11596A","-11597A","-11598T","-11599G","-11600T","-11601T","-11602T","-11603A","-11604T","-11605A","-11606G","-11607T","-11608A","-11609C","-11610T","-11611A","-11612A","-11613G","-11614A","-11615A","-11616T","-11617T","-11618G","-11619G","-11620G","-11621C","-11622A","-11623A","-11624A","-11625C","-11626A","-11627T","-11628A","-11629A","-11630G","-11631A","-11632C","-11633A","-11634T","-11635G","-11636T","-11637C","-11638A","-11639C","-11640A","-11641A","-11642A","-11643G","-11644A","-11645C","-11646C","-11647C","-11648T","-11649T","-11650T","-11651T","-11652T","-11653G","-11654T","-11655A","-11656T","-11657G","-11658T","-11659A","-11660T","-11661A","-11662A","-11663G","-11664T","-11665G","-11666T","-11667A","-11668G","-11669A","-11670A","-11671A","-11672T","-11673T","-11674A","-11675T","-11676A","-11677A","-11678C","-11679A","-11680T","-11681C","-11682C","-11683A","-11684T","-11685A","-11686G","-11687T","-11688T","-11689G","-11690G","-11691A","-11692T","-11693T","-11694C","-11695A","-11696C","-11697A","-11698T","-11699A","-11700G","-11701G","-11702T","-11703G","-11704T","-11705C","-11706C","-11707A","-11708A","-11709T","-11710C","-11711G","-11712G","-11713G","-11714A","-11715T","-11716C","-11717T","-11718C","-11719T","-11720C","-11721C","-11722A","-11723T","-11724C","-11725A","-11726T","-11727C","-11728G","-11729A","-11730G","-11731A","-11732T","-11733G","-11734A","-11735T","-11736T","-11737G","-11738A","-11739C","-11740G","-11741G","-11742C","-11743A","-11744T","-11745C","-11746T","-11747C","-11748C","-11749C","-11750C","-11751C","-11752T","-11753T","-11754C","-11755C","-11756T","-11757T","-11758T","-11759T","-11760T","-11761T","-11762A","-11763G","-11764T","-11765A","-11766G","-11767A","-11768T","-11769A","-11770T","-11771T","-11772T","-11773C","-11774A","-11775T","-11776C","-11777G","-11778T","-11779G","-11780T","-11781A","-11782A","-11783G","-11784A","-11785A","-11786T","-11787C","-11788A","-11789A","-11790T","-11791A","-11792T","-11793T","-11794A","-11795A","-11796T","-11797A","-11798T","-11799T","-11800T","-11801C","-11802T","-11803A","-11804A","-11805A","-11806G","-11807T","-11808A","-11809T","-11810C","-11811T","-11812G","-11813T","-11814G","-11815T","-11816A","-11817T","-11818A","-11819G","-11820C","-11821C","-11822T","-11823C","-11824T","-11825T","-11826T","-11827A","-11828T","-11829T","-11830T","-11831A","-11832C","-11833C","-11834A","-11835C","-11836A","-11837G","-11838C","-11839T","-11840C","-11841C","-11842A","-11843T","-11844A","-11845T","-11846T","-11847C","-11848C","-11849A","-11850A","-11851C","-11852A","-11853T","-11854G","-11855C","-11856A","-11857T","-11858T","-11859C","-11860C","-11861A","-11862C","-11863T","-11864A","-11865G","-11866A","-11867G","-11868G","-11869G","-11870A","-11871T","-11872A","-11873T","-11874C","-11875G","-11876A","-11877T","-11878A","-11879T","-11880C","-11881G","-11882C","-11883C","-11884G","-11885A","-11886A","-11887T","-11888G","-11889T","-11890C","-11891A","-11892T","-11893A","-11894T","-11895A","-11896C","-11897T","-11898C","-11899A","-11900A","-11901T","-11902T","-11903A","-11904G","-11905T","-11906A","-11907T","-11908A","-11909T","-11910G","-11911T","-11912T","-11913G","-11914G","-11915A","-11916G","-11917G","-11918A","-11919C","-11920A","-11921T","-11922C","-11923C","-11924G","-11925A","-11926G","-11927T","-11928T","-11929C","-11930A","-11931T","-11932T","-11933G","-11934T","-11935T","-11936T","-11937T","-11938C","-11939A","-11940A","-11941T","-11942A","-11943T","-11944C","-11945A","-11946A","-11947A","-11948G","-11949A","-11950G","-11951A","-11952T","-11953G","-11954G","-11955T","-11956T","-11957T","-11958C","-11959C","-11960T","-11961T","-11962A","-11963T","-11964C","-11965A","-11966T","-11967T","-11968T","-11969C","-11970T","-11971C","-11972C","-11973A","-11974T","-11975A","-11976G","-11977T","-11978G","-11979G","-11980T","-11981A","-11982C","-11983A","-11984A","-11985T","-11986A","-11987C","-11988T","-11989A","-11990C","-11991A","-11992C","-11993A","-11994T","-11995T","-11996A","-11997T","-11998T","-11999C","-12000C","-12001G","-12002T","-12003A","-12004C","-12005G","-12006G","-12007C","-12008T","-12009T","-12010T","-12011C","-12012C","-12013A","-12014T","-12015T","-12016C","-12017T","-12018C","-12019C","-12020A","-12021A","-12022A","-12023A","-12024A","-12025C","-12026A","-12027A","-12028T","-12029T","-12030T","-12031T","-12032A","-12033C","-12034C","-12035A","-12036A","-12037A","-12038T","-12039C","-12040T","-12041A","-12042A","-12043A","-12044T","-12045C","-12046T","-12047A","-12048C","-12049A","-12050T","-12051C","-12052T","-12053T","-12054T","-12055A","-12056T","-12057T","-12058G","-12059T","-12060A","-12061T","-12062C","-12063T","-12064A","-12065T","-12066A","-12067A","-12068T","-12069C","-12070A","-12071C","-12072T","-12073A","-12074T","-12075T","-12076T","-12077A","-12078G","-12079A","-12080T","-12081A","-12082A","-12083T","-12084C","-12085A","-12086G","-12087C","-12088C","-12089A","-12090T","-12091A","-12092A","-12093T","-12094T","-12095C","-12096C","-12097T","-12098C","-12099G","-12100A","-12101G","-12102T","-12103G","-12104C","-12105A","-12106A","-12107C","-12108A","-12109T","-12110G","-12111T","-12112T","-12113A","-12114G","-12115A","-12116T","-12117C","-12118G","-12119T","-12120C","-12121T","-12122A","-12123T","-12124A","-12125T","-12126A","-12127T","-12128G","-12129A","-12130A","-12131T","-12132A","-12133A","-12134G","-12135C","-12136C","-12137G","-12138T","-12139G","-12140T","-12141T","-12142A","-12143T","-12144C","-12145T","-12146A","-12147T","-12148T","-12149C","-12150C","-12151T","-12152T","-12153T","-12154C","-12155A","-12156T","-12157T","-12158A","-12159A","-12160C","-12161A","-12162A","-12163T","-12164T","-12165T","-12166A","-12167A","-12168C","-12169G","-12170A","-12171T","-12172G","-12173T","-12174C","-12175T","-12176A","-12177T","-12178A","-12179T","-12180C","-12181T","-12182A","-12183T","-12184A","-12185T","-12186G","-12187A","-12188G","-12189A","-12190T","-12191G","-12192A","-12193C","-12194T","-12195T","-12196A","-12197A","-12198T","-12199A","-12200T","-12201A","-12202A","-12203T","-12204A","-12205T","-12206T","-12207G","-12208A","-12209A","-12210G","-12211A","-12212G","-12213C","-12214T","-12215G","-12216T","-12217A","-12218C","-12219A","-12220A","-12221T","-12222A","-12223G","-12224T","-12225T","-12226T","-12227T","-12228T","-12229A","-12230T","-12231C","-12232T","-12233A","-12234T","-12235A","-12236G","-12237A","-12238A","G155157A"],"OPG181":["R249K"]},"labels":{"aa":"OPG181: R249K"}},"children":[{"name":"OP324473","node_attrs":{"div":561,"accession":"OP324473","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.9"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP324473/2022-07-04"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0156/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-04"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G778-","T779-","T196649-","C196650-"]}}},{"name":"OP555563","node_attrs":{"div":561,"accession":"OP555563","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.9"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555563/2022-08-11"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0487/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-11"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000111","node_attrs":{"div":559,"lineage":{"value":"B.1.17"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G12169A","G44960A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]},"labels":{"clade":"B.1.17"}},"children":[{"name":"OP440561","node_attrs":{"div":563,"accession":"OP440561","author":{"author":"Hemarajata,P.,Green,N.M.","value":"Hemarajata,P.,Green,N.M."},"lineage":{"value":"B.1.17"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP440561/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00038/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","C46117T","C148978T","C166214T","-179145T","T179244-","C187741T","T196627-","C196628-","T196629-"],"OPG065":["D123N"],"OPG174":["D140N"]},"labels":{"aa":"OPG065: D123N; OPG174: D140N"}}},{"name":"OP442552","node_attrs":{"div":559,"accession":"OP442552","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"lineage":{"value":"B.1.17"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP442552/2022-07-13"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00085/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-13"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G771-","T772-","G773-","A196789-","A196790-","T196791-"]}}},{"name":"OP748959","node_attrs":{"div":560,"accession":"OP748959","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP748959/2022-07-14"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00273/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-14"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T658-","A659-","T660-","A11160G"],"OPG023":["F581L"]},"labels":{"aa":"OPG023: F581L"}}},{"name":"OP890577","node_attrs":{"div":561,"accession":"OP890577","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP890577/2022-11-09"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00320/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-09"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C39334G","G164476A"],"OPG057":["A288P"],"OPG189":["E382K"]},"labels":{"aa":"OPG057: A288P; OPG189: E382K"}}},{"name":"NODE_0000112","node_attrs":{"div":560,"lineage":{"value":"B.1.17"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C177626T"]}},"children":[{"name":"OP580612","node_attrs":{"div":564,"accession":"OP580612","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP580612/2022-09-20"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMPX/USA/CA-LACPHL-MA00179/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-20"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C689-","G690-","A691-","G16986A","T73740A","G73745A","T126985C","A140156G"],"OPG093":["F255I","M256I"]},"labels":{"aa":"OPG093: F255I, M256I"}}},{"name":"OQ888843","node_attrs":{"div":562,"accession":"OQ888843","author":{"author":"Hemarajata,P.,Garrigues,J.M.,Green,N.M.","value":"Hemarajata,P.,Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.17"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ888843/2022-10-13"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00483/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-13"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T39397C","G86148A"],"OPG057":["N267D"]},"labels":{"aa":"OPG057: N267D"}}}]},{"name":"NODE_0000113","node_attrs":{"div":560,"lineage":{"value":"B.1.17"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A39395-","T39396-","T39397-","C85931T"],"OPG057":["N267-"]},"labels":{"aa":"OPG057: N267-"}},"children":[{"name":"OQ547885","node_attrs":{"div":562,"accession":"OQ547885","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"lineage":{"value":"B.1.17"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ547885/2023-01-10"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000178/2022"},"institution":{"value":"CDPH, VRDL"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-10"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G71249A","G182189A"],"OPG090":["R24Q"]},"labels":{"aa":"OPG090: R24Q"}}},{"name":"OQ503816","node_attrs":{"div":560,"accession":"OQ503816","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ503816/2022-12-02"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00423/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-02"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]}]},{"name":"NODE_0000114","node_attrs":{"div":558,"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C141757T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OR126131","node_attrs":{"div":562,"accession":"OR126131","author":{"author":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C.","value":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C."},"lineage":{"value":"B.1"},"country":{"value":"Spain"},"strain_display":{"value":"Spain/OR126131/2022-09-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"HRYC_MPXV001"},"institution":{"value":"Hospital Ramon y Cajal, Microbiology"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-21"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C11749-","C34432T","C48324T","G101294A","G190695A"],"OPG016":["E96K"],"OPG053":["E87K"],"OPG120":["S152L"]},"labels":{"aa":"OPG016: E96K; OPG053: E87K; OPG120: S152L"}}},{"name":"NODE_0000115","node_attrs":{"div":560,"lineage":{"value":"B.1.18"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C43706T","T124690C"]},"labels":{"clade":"B.1.18"}},"children":[{"name":"OP628451","node_attrs":{"div":560,"accession":"OP628451","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.18"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP628451/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-083401/2022"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OP890552","node_attrs":{"div":561,"accession":"OP890552","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.18"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP890552/2022-10-06"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00294/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-06"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T25432G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG040":["Y16S"]},"labels":{"aa":"OPG040: Y16S"}}},{"name":"OQ557948","node_attrs":{"div":565,"accession":"OQ557948","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"lineage":{"value":"B.1.18"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ557948/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_NY0009"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G24063A","C25370T","G54088A","G108462A","C159779T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG039":["S19F"],"OPG040":["E37K"],"OPG185":["S288L"]},"labels":{"aa":"OPG039: S19F; OPG040: E37K; OPG185: S288L"}}},{"name":"NODE_0000116","node_attrs":{"div":561,"lineage":{"value":"B.1.18"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C170049T"]}},"children":[{"name":"OQ320465","node_attrs":{"div":562,"accession":"OQ320465","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"lineage":{"value":"B.1.18"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ320465/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_NY0026"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G105147A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OQ503770","node_attrs":{"div":564,"accession":"OQ503770","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.18"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ503770/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-096758/2022"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G902A","T15127-","G87315A","C88489T","G111635A","C196308T"],"OPG001":["S225L"],"OPG001_dup":["S225L"],"OPG109":["R320K"],"OPG130":["P90S"]},"labels":{"aa":"OPG001: S225L; OPG001_dup: S225L; OPG109: R320K; OPG130: P90S"}}},{"name":"NODE_0000117","node_attrs":{"div":562,"lineage":{"value":"B.1.18"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G67758A"]}},"children":[{"name":"OP819956","node_attrs":{"div":563,"accession":"OP819956","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.18"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP819956/2022-10-12"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"VAC_INS_MPX_0965_EL"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-12"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G28913A"],"OPG045":["S117L"]},"labels":{"aa":"OPG045: S117L"}}},{"name":"OQ148474","node_attrs":{"div":566,"accession":"OQ148474","author":{"author":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"lineage":{"value":"B.1.18"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OQ148474/2022-11-15"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"LBMB-UTP_MP-025_VAC"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-15"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C128242T","G144572A","C166940T","C168829T"],"OPG150":["S155F"],"OPG166":["A59T"]},"labels":{"aa":"OPG150: S155F; OPG166: A59T"}}}]}]}]}]},{"name":"NODE_0000126","node_attrs":{"div":559,"lineage":{"value":"B.1.15"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","G149818A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G151362A"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG176":["D4N"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG176: D4N","clade":"B.1.15"}},"children":[{"name":"ON694335","node_attrs":{"div":559,"accession":"ON694335","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.15"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/ON694335/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI018"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-","A196614-"]}}},{"name":"OP324453","node_attrs":{"div":560,"accession":"OP324453","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.15"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP324453/2022-07-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0129/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-12"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","C18133T","-196615A","-196616T"]}}},{"name":"OP484673","node_attrs":{"div":562,"accession":"OP484673","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.15"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP484673/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI352"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C21128T","G74187T","C151111T"],"OPG037":["E436K"],"OPG094":["Q136H"]},"labels":{"aa":"OPG037: E436K; OPG094: Q136H"}}},{"name":"OP764619","node_attrs":{"div":559,"accession":"OP764619","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.15"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP764619/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI561"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OP693654","node_attrs":{"div":559,"accession":"OP693654","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"lineage":{"value":"B.1.15"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP693654/2022-08-23"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"DC_INS_MPX_0722_L"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-23"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A2840-","T2841-","C2842-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"NODE_0000127","node_attrs":{"div":563,"lineage":{"value":"B.1.15"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C8385T","-11326A","-11327T","-11328C","-11329T","-11330A","-11331C","-11332G","-11333A","-11334T","-11335A","-11336T","-11337T","-11338A","-11339G","-11340A","-11341T","-11342A","-11343C","-11344T","-11345T","-11346C","-11347A","-11348C","-11349T","-11350C","-11351A","-11352A","-11353T","-11354G","-11355A","-11356A","-11357T","-11358C","-11359A","-11360A","-11361T","-11362C","-11363A","-11364C","-11365A","-11366C","-11367A","-11368A","-11369T","-11370C","-11371T","-11372A","-11373A","-11374T","-11375G","-11376T","-11377A","-11378G","-11379G","-11380T","-11381T","-11382T","-11383A","-11384T","-11385G","-11386A","-11387C","-11388A","-11389T","-11390A","-11391A","-11392T","-11393A","-11394G","-11395C","-11396A","-11397T","-11398T","-11399T","-11400T","-11401C","-11402A","-11403G","-11404C","-11405A","-11406G","-11407T","-11408T","-11409C","-11410A","-11411A","-11412T","-11413G","-11414T","-11415T","-11416T","-11417C","-11418T","-11419A","-11420G","-11421A","-11422T","-11423T","-11424C","-11425G","-11426T","-11427T","-11428G","-11429A","-11430T","-11431G","-11432G","-11433C","-11434A","-11435A","-11436T","-11437G","-11438G","-11439T","-11440T","-11441A","-11442T","-11443A","-11444C","-11445A","-11446T","-11447G","-11448T","-11449A","-11450T","-11451A","-11452T","-11453C","-11454C","-11455G","-11456T","-11457T","-11458A","-11459T","-11460T","-11461T","-11462G","-11463A","-11464T","-11465C","-11466T","-11467A","-11468A","-11469T","-11470G","-11471T","-11472T","-11473G","-11474A","-11475C","-11476A","-11477T","-11478C","-11479T","-11480G","-11481A","-11482A","-11483C","-11484C","-11485G","-11486G","-11487A","-11488T","-11489T","-11490C","-11491T","-11492A","-11493G","-11494C","-11495A","-11496G","-11497T","-11498A","-11499A","-11500A","-11501G","-11502A","-11503T","-11504A","-11505C","-11506T","-11507A","-11508G","-11509A","-11510G","-11511A","-11512T","-11513T","-11514G","-11515T","-11516T","-11517T","-11518A","-11519T","-11520T","-11521A","-11522T","-11523A","-11524T","-11525C","-11526T","-11527A","-11528A","-11529C","-11530A","-11531G","-11532C","-11533C","-11534T","-11535T","-11536G","-11537T","-11538G","-11539A","-11540A","-11541G","-11542A","-11543A","-11544G","-11545T","-11546G","-11547T","-11548T","-11549T","-11550C","-11551T","-11552C","-11553C","-11554T","-11555C","-11556G","-11557T","-11558T","-11559T","-11560G","-11561T","-11562C","-11563A","-11564A","-11565T","-11566C","-11567A","-11568T","-11569G","-11570T","-11571T","-11572A","-11573A","-11574T","-11575G","-11576T","-11577C","-11578T","-11579T","-11580T","-11581A","-11582A","-11583G","-11584A","-11585T","-11586A","-11587A","-11588G","-11589G","-11590T","-11591A","-11592G","-11593A","-11594C","-11595A","-11596A","-11597A","-11598T","-11599G","-11600T","-11601T","-11602T","-11603A","-11604T","-11605A","-11606G","-11607T","-11608A","-11609C","-11610T","-11611A","-11612A","-11613G","-11614A","-11615A","-11616T","-11617T","-11618G","-11619G","-11620G","-11621C","-11622A","-11623A","-11624A","-11625C","-11626A","-11627T","-11628A","-11629A","-11630G","-11631A","-11632C","-11633A","-11634T","-11635G","-11636T","-11637C","-11638A","-11639C","-11640A","-11641A","-11642A","-11643G","-11644A","-11645C","-11646C","-11647C","-11648T","-11649T","-11650T","-11651T","-11652T","-11653G","-11654T","-11655A","-11656T","-11657G","-11658T","-11659A","-11660T","-11661A","-11662A","-11663G","-11664T","-11665G","-11666T","-11667A","-11668G","-11669A","-11670A","-11671A","-11672T","-11673T","-11674A","-11675T","-11676A","-11677A","-11678C","-11679A","-11680T","-11681C","-11682C","-11683A","-11684T","-11685A","-11686G","-11687T","-11688T","-11689G","-11690G","-11691A","-11692T","-11693T","-11694C","-11695A","-11696C","-11697A","-11698T","-11699A","-11700G","-11701G","-11702T","-11703G","-11704T","-11705C","-11706C","-11707A","-11708A","-11709T","-11710C","-11711G","-11712G","-11713G","-11714A","-11715T","-11716C","-11717T","-11718C","-11719T","-11720C","-11721C","-11722A","-11723T","-11724C","-11725A","-11726T","-11727C","-11728G","-11729A","-11730G","-11731A","-11732T","-11733G","-11734A","-11735T","-11736T","-11737G","-11738A","-11739C","-11740G","-11741G","-11742C","-11743A","-11744T","-11745C","-11746T","-11747C","-11748C","-11749C","-11750C","-11751C","-11752T","-11753T","-11754C","-11755C","-11756T","-11757T","-11758T","-11759T","-11760T","-11761T","-11762A","-11763G","-11764T","-11765A","-11766G","-11767A","-11768T","-11769A","-11770T","-11771T","-11772T","-11773C","-11774A","-11775T","-11776C","-11777G","-11778T","-11779G","-11780T","-11781A","-11782A","-11783G","-11784A","-11785A","-11786T","-11787C","-11788A","-11789A","-11790T","-11791A","-11792T","-11793T","-11794A","-11795A","-11796T","-11797A","-11798T","-11799T","-11800T","-11801C","-11802T","-11803A","-11804A","-11805A","-11806G","-11807T","-11808A","-11809T","-11810C","-11811T","-11812G","-11813T","-11814G","-11815T","-11816A","-11817T","-11818A","-11819G","-11820C","-11821C","-11822T","-11823C","-11824T","-11825T","-11826T","-11827A","-11828T","-11829T","-11830T","-11831A","-11832C","-11833C","-11834A","-11835C","-11836A","-11837G","-11838C","-11839T","-11840C","-11841C","-11842A","-11843T","-11844A","-11845T","-11846T","-11847C","-11848C","-11849A","-11850A","-11851C","-11852A","-11853T","-11854G","-11855C","-11856A","-11857T","-11858T","-11859C","-11860C","-11861A","-11862C","-11863T","-11864A","-11865G","-11866A","-11867G","-11868G","-11869G","-11870A","-11871T","-11872A","-11873T","-11874C","-11875G","-11876A","-11877T","-11878A","-11879T","-11880C","-11881G","-11882C","-11883C","-11884G","-11885A","-11886A","-11887T","-11888G","-11889T","-11890C","-11891A","-11892T","-11893A","-11894T","-11895A","-11896C","-11897T","-11898C","-11899A","-11900A","-11901T","-11902T","-11903A","-11904G","-11905T","-11906A","-11907T","-11908A","-11909T","-11910G","-11911T","-11912T","-11913G","-11914G","-11915A","-11916G","-11917G","-11918A","-11919C","-11920A","-11921T","-11922C","-11923C","-11924G","-11925A","-11926G","-11927T","-11928T","-11929C","-11930A","-11931T","-11932T","-11933G","-11934T","-11935T","-11936T","-11937T","-11938C","-11939A","-11940A","-11941T","-11942A","-11943T","-11944C","-11945A","-11946A","-11947A","-11948G","-11949A","-11950G","-11951A","-11952T","-11953G","-11954G","-11955T","-11956T","-11957T","-11958C","-11959C","-11960T","-11961T","-11962A","-11963T","-11964C","-11965A","-11966T","-11967T","-11968T","-11969C","-11970T","-11971C","-11972C","-11973A","-11974T","-11975A","-11976G","-11977T","-11978G","-11979G","-11980T","-11981A","-11982C","-11983A","-11984A","-11985T","-11986A","-11987C","-11988T","-11989A","-11990C","-11991A","-11992C","-11993A","-11994T","-11995T","-11996A","-11997T","-11998T","-11999C","-12000C","-12001G","-12002T","-12003A","-12004C","-12005G","-12006G","-12007C","-12008T","-12009T","-12010T","-12011C","-12012C","-12013A","-12014T","-12015T","-12016C","-12017T","-12018C","-12019C","-12020A","-12021A","-12022A","-12023A","-12024A","-12025C","-12026A","-12027A","-12028T","-12029T","-12030T","-12031T","-12032A","-12033C","-12034C","-12035A","-12036A","-12037A","-12038T","-12039C","-12040T","-12041A","-12042A","-12043A","-12044T","-12045C","-12046T","-12047A","-12048C","-12049A","-12050T","-12051C","-12052T","-12053T","-12054T","-12055A","-12056T","-12057T","-12058G","-12059T","-12060A","-12061T","-12062C","-12063T","-12064A","-12065T","-12066A","-12067A","-12068T","-12069C","-12070A","-12071C","-12072T","-12073A","-12074T","-12075T","-12076T","-12077A","-12078G","-12079A","-12080T","-12081A","-12082A","-12083T","-12084C","-12085A","-12086G","-12087C","-12088C","-12089A","-12090T","-12091A","-12092A","-12093T","-12094T","-12095C","-12096C","-12097T","-12098C","-12099G","-12100A","-12101G","-12102T","-12103G","-12104C","-12105A","-12106A","-12107C","-12108A","-12109T","-12110G","-12111T","-12112T","-12113A","-12114G","-12115A","-12116T","-12117C","-12118G","-12119T","-12120C","-12121T","-12122A","-12123T","-12124A","-12125T","-12126A","-12127T","-12128G","-12129A","-12130A","-12131T","-12132A","-12133A","-12134G","-12135C","-12136C","-12137G","-12138T","-12139G","-12140T","-12141T","-12142A","-12143T","-12144C","-12145T","-12146A","-12147T","-12148T","-12149C","-12150C","-12151T","-12152T","-12153T","-12154C","-12155A","-12156T","-12157T","-12158A","-12159A","-12160C","-12161A","-12162A","-12163T","-12164T","-12165T","-12166A","-12167A","-12168C","-12169G","-12170A","-12171T","-12172G","-12173T","-12174C","-12175T","-12176A","-12177T","-12178A","-12179T","-12180C","-12181T","-12182A","-12183T","-12184A","-12185T","-12186G","-12187A","-12188G","-12189A","-12190T","-12191G","-12192A","-12193C","-12194T","-12195T","-12196A","-12197A","-12198T","-12199A","-12200T","-12201A","-12202A","-12203T","-12204A","-12205T","-12206T","-12207G","-12208A","-12209A","-12210G","-12211A","-12212G","-12213C","-12214T","-12215G","-12216T","-12217A","-12218C","-12219A","-12220A","-12221T","-12222A","-12223G","-12224T","-12225T","-12226T","-12227T","-12228T","-12229A","-12230T","-12231C","-12232T","-12233A","-12234T","-12235A","-12236G","-12237A","-12238A","G40242A","C40335T","G139582A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG023":["-222S","-223I","-224D","-225K","-226N","-227Y","-228C","-229T","-230A","-231L","-232Q","-233Y","-234Y","-235I","-236K","-237S","-238S","-239H","-240I","-241D","-242I","-243D","-244I","-245V","-246K","-247L","-248L","-249M","-250K","-251G","-252I","-253D","-254N","-255T","-256A","-257Y","-258S","-259Y","-260I","-261D","-262D","-263L","-264T","-265C","-266C","-267T","-268R","-269G","-270I","-271M","-272A","-273D","-274Y","-275L","-276N","-277S","-278D","-279Y","-280R","-281Y","-282N","-283K","-284D","-285V","-286D","-287L","-288D","-289L","-290V","-291K","-292L","-293F","-294L","-295E","-296N","-297G","-298K","-299P","-300Y","-301G","-302I","-303M","-304C","-305S","-306I","-307V","-308P","-309L","-310W","-311R","-312N","-313D","-314K","-315E","-316T","-317I","-318S","-319L","-320I","-321L","-322K","-323T","-324M","-325N","-326S","-327D","-328V","-329L","-330Q","-331H","-332I","-333L","-334I","-335E","-336Y","-337M","-338T","-339F","-340G","-341D","-342I","-343D","-344I","-345P","-346L","-347V","-348E","-349C","-350M","-351L","-352E","-353Y","-354G","-355A","-356V","-357V","-358N","-359K","-360E","-361A","-362I","-363H","-364R","-365Y","-366F","-367R","-368N","-369I","-370N","-371I","-372D","-373S","-374Y","-375T","-376M","-377K","-378Y","-379L","-380L","-381K","-382K","-383E","-384G","-385G","-386D","-387A","-388V","-389N","-390H","-391L","-392D","-393D","-394G","-395E","-396I","-397P","-398I","-399G","-400H","-401L","-402C","-403E","-404S","-405N","-406Y","-407G","-408C","-409Y","-410N","-411F","-412Y","-413T","-414Y","-415T","-416Y","-417K","-418K","-419G","-420L","-421C","-422D","-423M","-424S","-425Y","-426V","-427C","-428P","-429I","-430L","-431S","-432T","-433I","-434N","-435I","-436C","-437L","-438P","-439Y","-440L","-441K","-442D","-443I","-444N","-445M","-446I","-447D","-448K","-449R","-450G","-451E","-452T","-453L","-454L","-455H","-456K","-457A","-458V","-459R","-460Y","-461N","-462K","-463Q","-464S","-465L","-466V","-467S","-468L","-469L","-470L","-471E","-472S","-473G","-474S","-475D","-476V","-477N","-478I","-479R","-480S","-481N","-482N","-483G","-484Y","-485T","-486C","-487I","-488T","-489I","-490A","-491I","-492N","-493E","-494S","-495R","-496N","-497I","-498E","-499L","-500L","-501K","-502M","-503L","-504L","-505C","-506H","-507K","-508P","-509T","-510L","-511D","-512C","-513V","-514I","-515D","-516S","-517L","-518S","-519E","-520V","-521S","-522N","-523I","-524V","-525D"],"OPG058":["E34K"]},"labels":{"aa":"OPG023: -222S, -223I, -224D, -225K, -226N, -227Y, -228C, -229T, -230A, -231L, -232Q, -233Y, -234Y, -235I, -236K, -237S, -238S, -239H, -240I, -241D, -242I, -243D, -244I, -245V, -246K, -247L, -248L, -249M, -250K, -251G, -252I, -253D, -254N, -255T, -256A, -257Y, -258S, -259Y, -260I, -261D, -262D, -263L, -264T, -265C, -266C, -267T, -268R, -269G, -270I, -271M, -272A, -273D, -274Y, -275L, -276N, -277S, -278D, -279Y, -280R, -281Y, -282N, -283K, -284D, -285V, -286D, -287L, -288D, -289L, -290V, -291K, -292L, -293F, -294L, -295E, -296N, -297G, -298K, -299P, -300Y, -301G, -302I, -303M, -304C, -305S, -306I, -307V, -308P, -309L, -310W, -311R, -312N, -313D, -314K, -315E, -316T, -317I, -318S, -319L, -320I, -321L, -322K, -323T, -324M, -325N, -326S, -327D, -328V, -329L, -330Q, -331H, -332I, -333L, -334I, -335E, -336Y, -337M, -338T, -339F, -340G, -341D, -342I, -343D, -344I, -345P, -346L, -347V, -348E, -349C, -350M, -351L, -352E, -353Y, -354G, -355A, -356V, -357V, -358N, -359K, -360E, -361A, -362I, -363H, -364R, -365Y, -366F, -367R, -368N, -369I, -370N, -371I, -372D, -373S, -374Y, -375T, -376M, -377K, -378Y, -379L, -380L, -381K, -382K, -383E, -384G, -385G, -386D, -387A, -388V, -389N, -390H, -391L, -392D, -393D, -394G, -395E, -396I, -397P, -398I, -399G, -400H, -401L, -402C, -403E, -404S, -405N, -406Y, -407G, -408C, -409Y, -410N, -411F, -412Y, -413T, -414Y, -415T, -416Y, -417K, -418K, -419G, -420L, -421C, -422D, -423M, -424S, -425Y, -426V, -427C, -428P, -429I, -430L, -431S, -432T, -433I, -434N, -435I, -436C, -437L, -438P, -439Y, -440L, -441K, -442D, -443I, -444N, -445M, -446I, -447D, -448K, -449R, -450G, -451E, -452T, -453L, -454L, -455H, -456K, -457A, -458V, -459R, -460Y, -461N, -462K, -463Q, -464S, -465L, -466V, -467S, -468L, -469L, -470L, -471E, -472S, -473G, -474S, -475D, -476V, -477N, -478I, -479R, -480S, -481N, -482N, -483G, -484Y, -485T, -486C, -487I, -488T, -489I, -490A, -491I, -492N, -493E, -494S, -495R, -496N, -497I, -498E, -499L, -500L, -501K, -502M, -503L, -504L, -505C, -506H, -507K, -508P, -509T, -510L, -511D, -512C, -513V, -514I, -515D, -516S, -517L, -518S, -519E, -520V, -521S, -522N, -523I, -524V, -525D; OPG058: E34K"}},"children":[{"name":"OP642402","node_attrs":{"div":565,"accession":"OP642402","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.15"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP642402/2022-09-12"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"ANT-LDSP-ANT-MPX-24957C"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-09-12"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G125388A","G126763A","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-"],"OPG145":["R481H"],"OPG148":["E260K"]},"labels":{"aa":"OPG145: R481H; OPG148: E260K"}}},{"name":"NODE_0000128","node_attrs":{"div":564,"lineage":{"value":"B.1.15"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C127609T"]}},"children":[{"name":"OP819950","node_attrs":{"div":566,"accession":"OP819950","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.15"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP819950/2022-10-12"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"MET_INS_MPX_0956_C"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-12"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G144284A","C171808T","G196973-","A196974-","A196975-"],"OPG165":["D257N"],"OPG199":["S274L"]},"labels":{"aa":"OPG165: D257N; OPG199: S274L"}}},{"name":"OR035721","node_attrs":{"div":566,"accession":"OR035721","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.15"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR035721/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_115"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C21324T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G180556A","T196712-","A196713-","T196714-"]}}},{"name":"OR086972","node_attrs":{"div":569,"accession":"OR086972","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.15"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR086972/2022-07-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_163/Belgium/2022"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-27"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G31180A","C142626T","G158549A","G159341A","C170750T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG163":["S142L"],"OPG185":["G142E"],"OPG198":["A238V"]},"labels":{"aa":"OPG163: S142L; OPG185: G142E; OPG198: A238V"}}}]}]}]},{"name":"NODE_0000136","node_attrs":{"div":558,"lineage":{"value":"B.1.13"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G175093A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C"],"OPG204":["D188N"]},"labels":{"aa":"OPG204: D188N","clade":"B.1.13"}},"children":[{"name":"OP442564","node_attrs":{"div":561,"accession":"OP442564","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"lineage":{"value":"B.1.13"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP442564/2022-08-02"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00096/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-02"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C629-","C630-","A631-","C55472T","G55632A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G167713A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"],"OPG074":["D552N"],"OPG193":["R127K"]},"labels":{"aa":"OPG074: D552N; OPG193: R127K"}}},{"name":"OP536663","node_attrs":{"div":560,"accession":"OP536663","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"lineage":{"value":"B.1.13"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP536663/2022-08-04"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV-USA-IL-IDPH-002"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-04"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G119424A","G125452A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG136":["S55L"],"OPG146":["S63L"]},"labels":{"aa":"OPG136: S55L; OPG146: S63L"}}},{"name":"NODE_0000137","node_attrs":{"div":563,"lineage":{"value":"B.1.13"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G22814A","G55162A","C118921T","G137128A","G167910A","A173316-","T173317-","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG038":["H116Y"],"OPG074":["S655L"],"OPG136":["D223N"],"OPG193":["E193K"]},"labels":{"aa":"OPG038: H116Y; OPG074: S655L; OPG136: D223N; OPG193: E193K"}},"children":[{"name":"OQ320456","node_attrs":{"div":563,"accession":"OQ320456","author":{"author":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y.","value":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y."},"lineage":{"value":"B.1.13"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ320456/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_KS0004"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T"]}}},{"name":"OQ721921","node_attrs":{"div":564,"accession":"OQ721921","author":{"author":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y.","value":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y."},"lineage":{"value":"B.1.13"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ721921/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_KS0005"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C110297T","A173314-","T173315-"]}}}]},{"name":"NODE_0000138","node_attrs":{"div":559,"lineage":{"value":"B.1.13"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C132520T"]}},"children":[{"name":"OP257254","node_attrs":{"div":559,"accession":"OP257254","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.13"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP257254/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/OH-UW-073812/2022"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR160418","node_attrs":{"div":566,"accession":"OR160418","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.13"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR160418/2023-05-10"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-052-0034/2023"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-05-10"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C27520T","G58883A","G99832A","G102186A","G129583A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G171410A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","C182950T"],"OPG043":["A146T"],"OPG118":["D463N"],"OPG121":["E133K"],"OPG210":["S532L"]},"labels":{"aa":"OPG043: A146T; OPG118: D463N; OPG121: E133K; OPG210: S532L"}}},{"name":"NODE_0000139","node_attrs":{"div":560,"lineage":{"value":"B.1.13"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G165086A"]}},"children":[{"name":"OP536666","node_attrs":{"div":561,"accession":"OP536666","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"lineage":{"value":"B.1.13"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP536666/2022-06-30"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV-USA-IL-IDPH-005"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-30"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C169529T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"OR209321","node_attrs":{"div":561,"accession":"OR209321","author":{"author":"Gigante,C.,Ostadkar,R.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,X.,Li,Y.","value":"Gigante,C.,Ostadkar,R.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,X.,Li,Y."},"lineage":{"value":"B.1.13"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR209321/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_MN0014"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G143463A","C179190-"]}}}]},{"name":"NODE_0000140","node_attrs":{"div":560,"lineage":{"value":"B.1.13"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C21383T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG037":["G351S"]},"labels":{"aa":"OPG037: G351S"}},"children":[{"name":"OQ319139","node_attrs":{"div":562,"accession":"OQ319139","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.13"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ319139/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI681"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C24584T","G27462A","G150551-","A150569-","T150570-","A150571-","T150572-","G150573-","A150574-","T150575-","G150576-","A152676-","T152686-"],"OPG040":["D299N"],"OPG043":["S165L"]},"labels":{"aa":"OPG040: D299N; OPG043: S165L"}}},{"name":"OQ773520","node_attrs":{"div":563,"accession":"OQ773520","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.13"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ773520/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI901"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G85431A","C146446T","C147140T","-179194A","-179195T","C179265-","A179266-","T179267-"],"OPG106":["S23F"],"OPG170":["M111I"]},"labels":{"aa":"OPG106: S23F; OPG170: M111I"}}}]}]}]},{"name":"NODE_0000168","node_attrs":{"div":558,"lineage":{"value":"B.1.6"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G111029A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]},"labels":{"clade":"B.1.6"}},"children":[{"name":"OP289783","node_attrs":{"div":558,"accession":"OP289783","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Mestanza,O.,Lope,P.,Nunez,A.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Mestanza,O.,Lope,P.,Nunez,A."},"lineage":{"value":"B.1.6"},"country":{"value":"Peru"},"strain_display":{"value":"Peru/OP289783/2022-06-27"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"LIM-INS-003"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-27"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OP431402","node_attrs":{"div":559,"accession":"OP431402","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.6"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP431402/2022-08-18"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"ANT-LDSP-ANT-MPX-22752-O"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-18"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G15814A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP536765","node_attrs":{"div":560,"accession":"OP536765","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.6"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP536765/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"9000387"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G59112A","C87978T"]}}},{"name":"OQ503831","node_attrs":{"div":562,"accession":"OQ503831","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.6"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ503831/2023-01-11"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00408/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-11"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","G10945A","G39515A","C44627T","G56276A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A196614-"],"OPG064":["M424I"]},"labels":{"aa":"OPG064: M424I"}}},{"name":"OP320551","node_attrs":{"div":558,"accession":"OP320551","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"lineage":{"value":"B.1.6"},"country":{"value":"Peru"},"strain_display":{"value":"Peru/OP320551/2022-07-09"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"LIM-INS-018"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-09"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OP289782","node_attrs":{"div":558,"accession":"OP289782","author":{"author":"Silva,I.,Jimenez,V.,Hurtado,V.,Barcena,L.","value":"Silva,I.,Jimenez,V.,Hurtado,V.,Barcena,L."},"lineage":{"value":"B.1.6"},"country":{"value":"Peru"},"strain_display":{"value":"Peru/OP289782/2022-06-25"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"LIM-INS-001"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-25"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-196615A","-196616A","-196617A"]}}},{"name":"NODE_0000094","node_attrs":{"div":559,"lineage":{"value":"B.1.6"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G132863A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A181356-","T181357-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","A181366-","A181368-","A181369-","A181370-","T181371-","T181372-"]}},"children":[{"name":"OP642401","node_attrs":{"div":559,"accession":"OP642401","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.6"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP642401/2022-09-12"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"ANT-LDSP-ANT-MPX-24947E"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-09-12"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C181355-","G181358-","C181365-","G181367-"]}}},{"name":"OQ696099","node_attrs":{"div":562,"accession":"OQ696099","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.6"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OQ696099/2022-11-09"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"ANT-LDSP-ANT-MPX-30518C"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-09"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G63811A","G167862A","C170130T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","-181356A","-181357T","-181359A","-181360A","-181361T","-181362T","-181363T","-181364T","-181366A","-181368A","-181369A","-181370A","-181371T","-181372T"],"OPG193":["D177N"]},"labels":{"aa":"OPG193: D177N"}}}]},{"name":"NODE_0000134","node_attrs":{"div":559,"lineage":{"value":"B.1.6"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G150364A"],"OPG176":["E186K"]},"labels":{"aa":"OPG176: E186K"}},"children":[{"name":"OP819947","node_attrs":{"div":559,"accession":"OP819947","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.6"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP819947/2022-10-14"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"CUN_INS_MPX_0951_C"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-14"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"]}}},{"name":"OQ348868","node_attrs":{"div":560,"accession":"OQ348868","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"lineage":{"value":"B.1.6"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ348868/2022-09-20"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000120/2022"},"institution":{"value":"CDPH, VRDL"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-20"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","C166930T"],"OPG192":["S67L"]},"labels":{"aa":"OPG192: S67L"}}}]},{"name":"NODE_0000135","node_attrs":{"div":563,"lineage":{"value":"B.1.6"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C14098T","C84063T","G142493A","G151324A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C187332T"],"OPG163":["D98N"],"OPG198":["S179L"]},"labels":{"aa":"OPG163: D98N; OPG198: S179L"}},"children":[{"name":"OQ503814","node_attrs":{"div":567,"accession":"OQ503814","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.6"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ503814/2022-12-03"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00421/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-03"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A11160G","G97749A","C108851T","G188726A"],"OPG023":["F581L"],"OPG128":["D69N"]},"labels":{"aa":"OPG023: F581L; OPG128: D69N"}}},{"name":"OR499960","node_attrs":{"div":569,"accession":"OR499960","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.6"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR499960/2023-03-15"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00503/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-15"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G6746A","C39266T","C63819T","G106927A","G138862A","G169213A","C170573T"],"OPG083":["V300I"],"OPG125":["T243M"],"OPG156":["S183F"]},"labels":{"aa":"OPG083: V300I; OPG125: T243M; OPG156: S183F"}}}]}]},{"name":"NODE_0000145","node_attrs":{"div":559,"lineage":{"value":"B.1.19"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G9963A","C148268T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG021":["R126K"]},"labels":{"aa":"OPG021: R126K","clade":"B.1.19"}},"children":[{"name":"OP270026","node_attrs":{"div":559,"accession":"OP270026","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.19"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OP270026/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/CAN/UN-NML-4017/2022"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-196615A","-196616A","-196617A"]}}},{"name":"OP838893","node_attrs":{"div":560,"accession":"OP838893","author":{"author":"Viscardi,M.,Cozzolino,L.,De Martinis,C.,Cardillo,L.,Fusco,G.","value":"Viscardi,M.,Cozzolino,L.,De Martinis,C.,Cardillo,L.,Fusco,G."},"lineage":{"value":"B.1.19"},"country":{"value":"Italy"},"strain_display":{"value":"Italy/OP838893/2022-06-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"ID6821"},"institution":{"value":"Istituto Zooprofilattico Sperimentale del Mezzogiorno, Hanimal Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-21"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","T29758C","T133100-","T133101-","T133102-","C133103-","G133104-","A133105-","A133106-","T133107-","T133108-","C133109-","A133110-","C133111-","G133112-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A157678-","A157679-","A157680-","A157681-","T157682-","T157683-","T157684-","T157685-","A157686-","A157687-","G157688-","C157689-","G157690-","A157691-","T157692-","G157693-","A157694-","T157695-","A157696-","T163214-","C163215-","T163216-","T163217-","A163218-","T163219-","A163220-","T163221-","A163417-","A163418-","T163419-","T163420-","C163421-","T163422-","T163423-","C163424-","C163425-","T169721A","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","G174537-","A174538-","T174539-","G174540-","A174541-","A174542-","A180482-","T180483-","T180484-","A180485-","A180486-","A180487-","A180488-","A180489-","A181114-","T181115-","T181116-","C181117-","C181118-","T181119-","T181120-","A181121-","T181122-","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-"],"OPG159":["N124-","Y125-","N126-"],"OPG189":["N29-","S30-","S31-"],"OPG197":["S18T"]},"labels":{"aa":"OPG159: N124-, Y125-, N126-; OPG189: N29-, S30-, S31-; OPG197: S18T"}}},{"name":"OR035726","node_attrs":{"div":561,"accession":"OR035726","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.19"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR035726/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_120"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C22739T","G133104A","G133231A","T137560-","G164487A"],"OPG038":["E141K"]},"labels":{"aa":"OPG038: E141K"}}},{"name":"OR086965","node_attrs":{"div":564,"accession":"OR086965","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.19"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR086965/2022-07-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_156/Belgium/2022"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-27"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C71016T","G77415A","T133099-","T133100-","G133319A","C176069T","G181309A"],"OPG089":["S384L"]},"labels":{"aa":"OPG089: S384L"}}},{"name":"NODE_0000146","node_attrs":{"div":560,"lineage":{"value":"B.1.19"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G150003A","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"]}},"children":[{"name":"OP382486","node_attrs":{"div":563,"accession":"OP382486","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1.19"},"country":{"value":"France"},"strain_display":{"value":"France/OP382486/2022-07-07"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMPXV-IHU00009"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-07"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C38483T","C164272T","G175971A"],"OPG189":["R314C"],"OPG205":["E106K"]},"labels":{"aa":"OPG189: R314C; OPG205: E106K"}}},{"name":"OQ172215","node_attrs":{"div":564,"accession":"OQ172215","author":{"author":"Zeggagh,J.,Ferraris,O.,Salmona,M.,Tarantola,A.,Molina,J.M.,Delaugerre,C.","value":"Zeggagh,J.,Ferraris,O.,Salmona,M.,Tarantola,A.,Molina,J.M.,Delaugerre,C."},"lineage":{"value":"B.1.19"},"country":{"value":"France"},"strain_display":{"value":"France/OQ172215/2022-06-07"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV-1047"},"institution":{"value":"Hopital Saint Louis, Paris"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-07"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A2591G","A31053G","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133171-","C133172-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T133639-","A150635-","A152676-","T152686-","T155897A","C173533A","A179077T","A179079T","A179081T","C179082T","A179083T","A179086T","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","T194619C","T194627G"],"OPG002":["F54S"],"OPG002_dup":["F54S","C57G"],"OPG047":["C48R"]},"labels":{"aa":"OPG002: F54S; OPG002_dup: F54S, C57G; OPG047: C48R"}}},{"name":"OQ427121","node_attrs":{"div":561,"accession":"OQ427121","author":{"author":"Gigante,C.,Cogswell,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Grenz,L.,Li,Y.","value":"Gigante,C.,Cogswell,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Grenz,L.,Li,Y."},"lineage":{"value":"B.1.19"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ427121/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_OR0008"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","C150140T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"],"OPG176":["S111L"]},"labels":{"aa":"OPG176: S111L"}}},{"name":"OR095050","node_attrs":{"div":563,"accession":"OR095050","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.19"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR095050/2022-08-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_232/Belgium/2022"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-12"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G57033A","G77415A","G83609A","T133099-","T133100-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C196750-","T196751-","A196752-"]}}},{"name":"NODE_0000147","node_attrs":{"div":562,"lineage":{"value":"B.1.19"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A169944T","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C185326T","-196615A"],"OPG197":["E92V"],"OPG210":["S1324L"]},"labels":{"aa":"OPG197: E92V; OPG210: S1324L"}},"children":[{"name":"OP555643","node_attrs":{"div":563,"accession":"OP555643","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.19"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555643/2022-09-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0572/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-05"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","C55057T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-"],"OPG073":["E29K"]},"labels":{"aa":"OPG073: E29K"}}},{"name":"OQ159056","node_attrs":{"div":566,"accession":"OQ159056","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.19"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ159056/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI661"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C2652T","G9584A","C87741T","G98995A","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG002":["D34N"],"OPG118":["E184K"]},"labels":{"aa":"OPG002: D34N; OPG118: E184K"}}}]},{"name":"NODE_0000148","node_attrs":{"div":561,"lineage":{"value":"B.1.19"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C74417T"],"OPG094":["S213L"]},"labels":{"aa":"OPG094: S213L"}},"children":[{"name":"OP205108","node_attrs":{"div":561,"accession":"OP205108","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.19"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP205108/2022-06-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_UK_2022_9000145"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-16"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OP413717","node_attrs":{"div":561,"accession":"OP413717","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.19"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP413717/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"9000353"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OP555533","node_attrs":{"div":562,"accession":"OP555533","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.19"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555533/2022-08-04"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0452/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-04"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-609T","G610-","T611-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C177833T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP536781","node_attrs":{"div":562,"accession":"OP536781","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.19"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP536781/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"9000405"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","C62868T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"]}}}]}]}]},{"name":"NODE_0000149","node_attrs":{"div":558,"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","G53326A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-196615A"]}},"children":[{"name":"OR264430","node_attrs":{"div":560,"accession":"OR264430","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain_display":{"value":"Australia/OR264430/2022-09-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"},"strain":{"value":"51_B"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-05"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C15582T","C121104T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG138":["R10K"]},"labels":{"aa":"OPG138: R10K"}}},{"name":"NODE_0000150","node_attrs":{"div":560,"lineage":{"value":"B.1.20"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T133099-","C164385T","C187620T"]},"labels":{"clade":"B.1.20"}},"children":[{"name":"OQ320441","node_attrs":{"div":560,"accession":"OQ320441","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ320441/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_TX0040"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"]}}},{"name":"OQ054239","node_attrs":{"div":561,"accession":"OQ054239","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ054239/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_TX0017"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-133099T","G176549A","-179194A","-179195T","-179196A","-179197T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG205":["M298I"]},"labels":{"aa":"OPG205: M298I"}}},{"name":"OQ427125","node_attrs":{"div":562,"accession":"OQ427125","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ427125/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_TX0044"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G48645A","G130027A","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-"],"OPG068":["E149K"]},"labels":{"aa":"OPG068: E149K"}}},{"name":"NODE_0000151","node_attrs":{"div":561,"lineage":{"value":"B.1.20"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T602-","T603-","T604-","T605-","T606-","T607-","-133099T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177398A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A196610-","A196611-","A196612-","A196613-","A196614-","A196615-"]}},"children":[{"name":"OQ427126","node_attrs":{"div":563,"accession":"OQ427126","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ427126/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_TX0045"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G36027A","C72221T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A"],"OPG055":["R353C"],"OPG092":["E243K"]},"labels":{"aa":"OPG055: R353C; OPG092: E243K"}}},{"name":"OQ918695","node_attrs":{"div":561,"accession":"OQ918695","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ918695/2023-02-07"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00484/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-07"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ644783","node_attrs":{"div":561,"accession":"OQ644783","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ644783/2023-01-17"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00477/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-17"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T179179-","A179180-"]}}},{"name":"OR464208","node_attrs":{"div":563,"accession":"OR464208","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR464208/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_TX0055"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G129761A","G150577-","A150578-","T150579-","A150580-","T150581-","G150582-","A150583-","T150584-","G150585-","T165597C","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG151":["D280N"],"OPG190":["V159A"]},"labels":{"aa":"OPG151: D280N; OPG190: V159A"}}},{"name":"NODE_0000152","node_attrs":{"div":562,"lineage":{"value":"B.1.20"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-602T","C177899T","T179179-","A179180-"]}},"children":[{"name":"OR665164","node_attrs":{"div":566,"accession":"OR665164","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR665164/2023-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-098659/2023"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G141131A","G146690A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C159608T","G163900-","A163901-","A163902-","T163903-","C163904-","A163905-","G168964A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A192393C","G192396A","A192402G","-196610A"],"OPG170":["S30F"],"OPG185":["S231F"],"OPG189":["E190-","S191-"]},"labels":{"aa":"OPG170: S30F; OPG185: S231F; OPG189: E190-, S191-"}}},{"name":"OR499966","node_attrs":{"div":563,"accession":"OR499966","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR499966/2023-03-31"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00509/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-31"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G115293A"],"OPG133":["A135V"]},"labels":{"aa":"OPG133: A135V"}}},{"name":"NODE_0000153","node_attrs":{"div":564,"lineage":{"value":"B.1.20"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-603T","-604T","-605T","-606T","C20453T","T164946C"]}},"children":[{"name":"OR449306","node_attrs":{"div":564,"accession":"OR449306","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.20"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OR449306/2023-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2023/RKI1020"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"]}}},{"name":"OR574863","node_attrs":{"div":564,"accession":"OR574863","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR574863/2023-05-16"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0054/2023"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-05-16"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G625-","A626-","G627-"]}}},{"name":"OR499989","node_attrs":{"div":564,"accession":"OR499989","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR499989/2023-06-26"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00533/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-06-26"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR499954","node_attrs":{"div":564,"accession":"OR499954","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR499954/2023-04-28"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00497/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-04-28"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000154","node_attrs":{"div":566,"lineage":{"value":"B.1.20"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C174050T","C180618T","T196627-","C196628-","T196629-"],"OPG209":["S34L"]},"labels":{"aa":"OPG209: S34L"}},"children":[{"name":"OR725693","node_attrs":{"div":568,"accession":"OR725693","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR725693/2023-08-18"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0099/2023"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-08-18"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C105798T","G148126A","T196633-","C196634-","T196635-"]}}},{"name":"OR473613","node_attrs":{"div":566,"accession":"OR473613","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR473613/2023-07-21"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0089/2023"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-07-21"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}}]}]}]}]}]}]},{"name":"NODE_0000155","node_attrs":{"div":561,"lineage":{"value":"B.1.11"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C18133T","G67611A","G130231A","G159277A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG185":["E121K"]},"labels":{"aa":"OPG185: E121K","clade":"B.1.11"}},"children":[{"name":"OP169336","node_attrs":{"div":561,"accession":"OP169336","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.11"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP169336/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-070499/2022"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A"]}}},{"name":"OP390178","node_attrs":{"div":561,"accession":"OP390178","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.11"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP390178/2022-08-20"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"MAG-UNIMOL-MPX-292982-L"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-20"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP555545","node_attrs":{"div":561,"accession":"OP555545","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.11"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555545/2022-08-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0466/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-05"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP536700","node_attrs":{"div":561,"accession":"OP536700","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"lineage":{"value":"B.1.11"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP536700/2022-06-19"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV-USA-IL-IDPH-039"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-19"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A","-196616A","-196617A"]}}},{"name":"OP524006","node_attrs":{"div":562,"accession":"OP524006","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.11"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP524006/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI404"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G182634A","-196615A"],"OPG210":["D427N"]},"labels":{"aa":"OPG210: D427N"}}},{"name":"OP819960","node_attrs":{"div":564,"accession":"OP819960","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.11"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP819960/2022-10-17"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"SAN_INS_MPX_0973_L"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-17"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A19748-","G19749-","G19750-","C19751-","G19752-","T19753-","G27840A","C64404T","C96810T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG034":["T87-","P88-"],"OPG043":["S39F"],"OPG083":["D105N"]},"labels":{"aa":"OPG034: T87-, P88-; OPG043: S39F; OPG083: D105N"}}},{"name":"OQ148467","node_attrs":{"div":565,"accession":"OQ148467","author":{"author":"Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"lineage":{"value":"B.1.11"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OQ148467/2022-09-13"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"LBMB-UTP_MP-010_TOL"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-13"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C58682T","C92819T","C170573T","G178744A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG078":["G44S"],"OPG198":["S179L"]},"labels":{"aa":"OPG078: G44S; OPG198: S179L"}}},{"name":"OP920682","node_attrs":{"div":563,"accession":"OP920682","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"lineage":{"value":"B.1.11"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP920682/2022-11-09"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00344/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-09"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","G39327A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177273A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"],"OPG057":["A290V"],"OPG205":["D540N"]},"labels":{"aa":"OPG057: A290V; OPG205: D540N"}}},{"name":"OR035719","node_attrs":{"div":564,"accession":"OR035719","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.11"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR035719/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_113"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T133099-","C142797T","C167995T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G189258A"],"OPG164":["S7L"],"OPG193":["S221F"]},"labels":{"aa":"OPG164: S7L; OPG193: S221F"}}},{"name":"OQ957072","node_attrs":{"div":564,"accession":"OQ957072","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.11"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OQ957072/2023-02-16"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"ANT-LDSP-ANT-MPX-3668E"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2023-02-16"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C35308T","G71777A","C120979T"],"OPG054":["R230H"],"OPG138":["D52N"]},"labels":{"aa":"OPG054: R230H; OPG138: D52N"}}},{"name":"OQ696101","node_attrs":{"div":565,"accession":"OQ696101","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.11"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OQ696101/2022-11-11"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"ANT-LDSP-ANT-MPX-30628C"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-11"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G17023A","G74462A","C80742T","G113382A"],"OPG029":["S16F"],"OPG094":["R228K"],"OPG104":["R93Q"]},"labels":{"aa":"OPG029: S16F; OPG094: R228K; OPG104: R93Q"}}},{"name":"OQ603477","node_attrs":{"div":562,"accession":"OQ603477","author":{"author":"Haw,M.,Kath,C.,Espinosa,A.,O'Neil,R.,Hacker,J.","value":"Haw,M.,Kath,C.,Espinosa,A.,O'Neil,R.,Hacker,J."},"lineage":{"value":"B.1.11"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ603477/2022-07-08"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000208/2023"},"institution":{"value":"CDPH, VRDL"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-08"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G23110A","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG038":["S17L"]},"labels":{"aa":"OPG038: S17L"}}},{"name":"OR095053","node_attrs":{"div":561,"accession":"OR095053","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.11"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR095053/2022-08-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_235/Belgium/2022"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-12"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"NODE_0000156","node_attrs":{"div":562,"lineage":{"value":"B.1.11"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C89777T"],"OPG110":["P49L"]},"labels":{"aa":"OPG110: P49L"}},"children":[{"name":"OP628481","node_attrs":{"div":562,"accession":"OP628481","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.11"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP628481/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-087818/2022"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-196615A"]}}},{"name":"OP743986","node_attrs":{"div":563,"accession":"OP743986","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.11"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP743986/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-098348/2022"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","G37469A","-196615A"]}}},{"name":"OP747058","node_attrs":{"div":564,"accession":"OP747058","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.11"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP747058/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-109000/2022"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G52594A","G176818A"],"OPG205":["R388Q"]},"labels":{"aa":"OPG205: R388Q"}}},{"name":"OR427333","node_attrs":{"div":562,"accession":"OR427333","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.11"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR427333/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-129402/2022"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000157","node_attrs":{"div":558,"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G34308A"],"OPG053":["S128L"]},"labels":{"aa":"OPG053: S128L","clade":"B.1.4"}},"children":[{"name":"ON880519","node_attrs":{"div":559,"accession":"ON880519","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/ON880519/2022-05-13"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/CAN/UN-NML-2833/2022"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-13"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T85846C"],"OPG107":["M112T"]},"labels":{"aa":"OPG107: M112T"}}},{"name":"NODE_0000158","node_attrs":{"div":561,"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C10672T","G112481A","G163626A"],"OPG022":["E63K"]},"labels":{"aa":"OPG022: E63K"}},"children":[{"name":"ON880511","node_attrs":{"div":562,"accession":"ON880511","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/ON880511/2022-05-30"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/CAN/UN-NML-3214/2022"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-30"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G144478A"]}}},{"name":"NODE_0000159","node_attrs":{"div":562,"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A87705G"]}},"children":[{"name":"OR126132","node_attrs":{"div":565,"accession":"OR126132","author":{"author":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C.","value":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C."},"lineage":{"value":"B.1.4"},"country":{"value":"Spain"},"strain_display":{"value":"Spain/OR126132/2023-03-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"HRYC_MPXV002"},"institution":{"value":"Hospital Ramon y Cajal, Microbiology"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-23"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G6376A","G11924A","G21674A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C190834T"],"OPG016":["S142L"],"OPG023":["S326L"],"OPG037":["L254F"]},"labels":{"aa":"OPG016: S142L; OPG023: S326L; OPG037: L254F"}}},{"name":"OR759153","node_attrs":{"div":565,"accession":"OR759153","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OR759153/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/Canada/ON-PHOL061/2022"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C99441T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C153642T","C183429T"],"OPG210":["P692S"]},"labels":{"aa":"OPG210: P692S"}}}]}]},{"name":"NODE_0000160","node_attrs":{"div":562,"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C24995T","G85774A","G148427A","G189258A"],"OPG040":["D162N"],"OPG107":["R88K"]},"labels":{"aa":"OPG040: D162N; OPG107: R88K"}},"children":[{"name":"ON983167","node_attrs":{"div":562,"accession":"ON983167","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/ON983167/2022-06-16"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/CAN/UN-NML-3725/2022"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-16"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"ON983163","node_attrs":{"div":562,"accession":"ON983163","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/ON983163/2022-06-07"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/CAN/UN-NML-3532/2022"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-07"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"ON880510","node_attrs":{"div":562,"accession":"ON880510","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/ON880510/2022-05-31"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/CAN/UN-NML-3193/2022"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-31"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OP279034","node_attrs":{"div":565,"accession":"OP279034","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OP279034/2022-07-04"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/CAN/UN-NML-4097/2022"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-04"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C93238T","G94798A","C97926T","-179191A","-179192T","-179194A","-179195T","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["S503L"],"OPG115":["E47K"]},"labels":{"aa":"OPG113: S503L; OPG115: E47K"}}},{"name":"OP415246","node_attrs":{"div":564,"accession":"OP415246","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.4"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP415246/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX_J6xzTO_9000286"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G45236A","G174962A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG204":["R144K"]},"labels":{"aa":"OPG204: R144K"}}},{"name":"OP536728","node_attrs":{"div":563,"accession":"OP536728","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"lineage":{"value":"B.1.4"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP536728/2022-06-25"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV-USA-IL-IDPH-067"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-25"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G131810A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG151":["D963N"]},"labels":{"aa":"OPG151: D963N"}}},{"name":"OR759181","node_attrs":{"div":565,"accession":"OR759181","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OR759181/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/Canada/ON-PHOL093/2022"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C24282T","G28334A","C47672T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG044":["E82K"]},"labels":{"aa":"OPG044: E82K"}}}]},{"name":"NODE_0000161","node_attrs":{"div":560,"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G36259A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G174543A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}},"children":[{"name":"OP626135","node_attrs":{"div":563,"accession":"OP626135","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.4"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP626135/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI496"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C40251T","C154472T","G167517A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"],"OPG058":["D62N"],"OPG181":["H21Y"],"OPG193":["E62K"]},"labels":{"aa":"OPG058: D62N; OPG181: H21Y; OPG193: E62K"}}},{"name":"OP722506","node_attrs":{"div":560,"accession":"OP722506","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.4"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP722506/2022-07-16"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00247/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-16"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000162","node_attrs":{"div":561,"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","C177720T","-196615A"],"OPG205":["R689C"]},"labels":{"aa":"OPG205: R689C"}},"children":[{"name":"OQ547900","node_attrs":{"div":562,"accession":"OQ547900","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"lineage":{"value":"B.1.4"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ547900/2022-12-21"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000185/2022"},"institution":{"value":"CDPH, VRDL"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-21"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G92733A"],"OPG113":["E335K"]},"labels":{"aa":"OPG113: E335K"}}},{"name":"OQ503748","node_attrs":{"div":563,"accession":"OQ503748","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.4"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ503748/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-108160/2022"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A80755C","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G159203A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG104":["C89G"],"OPG185":["G96E"]},"labels":{"aa":"OPG104: C89G; OPG185: G96E"}}}]},{"name":"NODE_0000163","node_attrs":{"div":561,"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C25967T"],"OPG042":["W377*"]},"labels":{"aa":"OPG042: W377*"}},"children":[{"name":"OP442553","node_attrs":{"div":562,"accession":"OP442553","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"lineage":{"value":"B.1.4"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP442553/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00086/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C188775T"]}}},{"name":"OP628490","node_attrs":{"div":561,"accession":"OP628490","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.4"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP628490/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-093570/2022"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP920681","node_attrs":{"div":563,"accession":"OP920681","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"lineage":{"value":"B.1.4"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP920681/2022-11-10"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00343/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-10"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A763-","A764-","T765-","C97805T","C172792T"],"OPG117":["P586L"]},"labels":{"aa":"OPG117: P586L"}}}]}]}]},{"name":"NODE_0000164","node_attrs":{"div":559,"lineage":{"value":"B.1.14"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G36617A","C159779T","-179194A","-179195T"],"OPG055":["S156L"],"OPG185":["S288L"]},"labels":{"aa":"OPG055: S156L; OPG185: S288L","clade":"B.1.14"}},"children":[{"name":"ON694342","node_attrs":{"div":559,"accession":"ON694342","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.14"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/ON694342/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI011"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179194-","T179195-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP378704","node_attrs":{"div":562,"accession":"OP378704","author":{"author":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y.","value":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y."},"lineage":{"value":"B.1.14"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP378704/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_TX0010"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C8552T","C8597T","G46179A","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A179194-","T179195-","-196615A","-196616A"],"OPG065":["S102L"]},"labels":{"aa":"OPG065: S102L"}}},{"name":"OP355572","node_attrs":{"div":560,"accession":"OP355572","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.14"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP355572/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI314"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C84008T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","A188351-"]}}},{"name":"OP626108","node_attrs":{"div":561,"accession":"OP626108","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.14"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP626108/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI470"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G53788A","G107868A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179194-","T179195-"],"OPG126":["S88F"]},"labels":{"aa":"OPG126: S88F"}}},{"name":"OQ319133","node_attrs":{"div":559,"accession":"OQ319133","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.14"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ319133/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI675"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A152676-","T152686-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OR449707","node_attrs":{"div":563,"accession":"OR449707","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.14"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OR449707/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI993"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C2459T","G90418A","C133943T","C134688T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG002":["R98Q"],"OPG111":["E52K"],"OPG193":["F263-"]},"labels":{"aa":"OPG002: R98Q; OPG111: E52K; OPG193: F263-"}}},{"name":"OR086995","node_attrs":{"div":560,"accession":"OR086995","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.14"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR086995/2022-08-03"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_186/Belgium/2022"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-03"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G146441A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG170":["S113F"]},"labels":{"aa":"OPG170: S113F"}}},{"name":"OR086956","node_attrs":{"div":562,"accession":"OR086956","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.14"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR086956/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_147/Belgium/2022"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C22880T","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","G158617A","C170573T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG038":["E94K"],"OPG198":["S179L"]},"labels":{"aa":"OPG038: E94K; OPG198: S179L"}}},{"name":"OX009124","node_attrs":{"div":561,"accession":"OX009124","author":{"author":"Pettke,A.,Filen,F.,Asgeirsson,H.,Glans,H.,Widgren,K.,Muradrasoli,S.,Helgesson,S.,Karlberg,M.L.,Walai,N.,Bjerkner,A.,Gourle,H.,Lindsjo,O.K.,Sonden,K.","value":"Pettke,A.,Filen,F.,Asgeirsson,H.,Glans,H.,Widgren,K.,Muradrasoli,S.,Helgesson,S.,Karlberg,M.L.,Walai,N.,Bjerkner,A.,Gourle,H.,Lindsjo,O.K.,Sonden,K."},"lineage":{"value":"B.1.14"},"country":{"value":"Sweden"},"strain_display":{"value":"Sweden/OX009124/2022-05-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Lesion"},"institution":{"value":"Public Health Agency of Sweden, Unit for Laboratory Development and Technology Transfer , Folkhalsomyndigheten, 171 82 Solna"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-22"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T602-","T603-","T604-","T605-","T606-","A8055-","A28531-","A28532-","T47054-","T76087-","T88836-","A91705-","A92907-","T103367-","T104687-","T148344A","A148345T","A151680-","A162904-","T163342-","T163597-","A170728-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG044":["M148-"],"OPG113":["I393-"],"OPG178":["T58-"],"OPG188":["K437-"],"OPG189":["F4-"],"OPG198":["K231-"]},"labels":{"aa":"OPG044: M148-; OPG113: I393-; OPG178: T58-; OPG188: K437-; OPG189: F4-; OPG198: K231-"}}},{"name":"ON959133","node_attrs":{"div":559,"accession":"ON959133","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"lineage":{"value":"B.1.14"},"country":{"value":"USA"},"strain_display":{"value":"USA/ON959133/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_NY002"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"]}}},{"name":"OP451009","node_attrs":{"div":559,"accession":"OP451009","author":{"author":"Gigante,C.M.,Pearson,C.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Maloney,M.,Li,Y.","value":"Gigante,C.M.,Pearson,C.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Maloney,M.,Li,Y."},"lineage":{"value":"B.1.14"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP451009/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_CT0002"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","T173277-","A173278-","T173279-","A173280-","T173281-","A173282-","T173283-","A173284-","T173285-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"]}}},{"name":"NODE_0000166","node_attrs":{"div":560,"lineage":{"value":"B.1.14"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G28021A"]}},"children":[{"name":"OP539922","node_attrs":{"div":562,"accession":"OP539922","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.14"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP539922/2022-08-09"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00137/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-09"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G109793A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G168211-","G168212-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A179194-","T179195-","G181818A"],"OPG210":["A155T"]},"labels":{"aa":"OPG210: A155T"}}},{"name":"OR026629","node_attrs":{"div":561,"accession":"OR026629","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"lineage":{"value":"B.1.14"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR026629/2022-09-09"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200382/2022"},"institution":{"value":"Utah Public Health Laboratory, Utah Public Health Laboratory Infectious Disease submission group"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-09"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C148666T"],"OPG174":["A244T"]},"labels":{"aa":"OPG174: A244T"}}}]},{"name":"NODE_0000167","node_attrs":{"div":560,"lineage":{"value":"B.1.14"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G171270A","A179194-","T179195-","-196615A"],"OPG199":["D95N"]},"labels":{"aa":"OPG199: D95N"}},"children":[{"name":"OP382492","node_attrs":{"div":561,"accession":"OP382492","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1.14"},"country":{"value":"France"},"strain_display":{"value":"France/OP382492/2022-07-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMPXV-IHU00015"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-22"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G161913A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196856-","A196857-","A196858-"]}}},{"name":"OP605553","node_attrs":{"div":560,"accession":"OP605553","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.14"},"country":{"value":"Slovenia"},"strain_display":{"value":"Slovenia/OP605553/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Slovenia-MPXV-10-2022"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T594A","-608T","-609T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","T196950-","A196951-","A196952-"]}}},{"name":"OP555644","node_attrs":{"div":562,"accession":"OP555644","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.14"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555644/2022-09-06"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0573/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-06"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T594A","-608T","-609T","C93713T","G158549A","-196616T"]}}},{"name":"OP555575","node_attrs":{"div":560,"accession":"OP555575","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.14"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555575/2022-08-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0501/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-16"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OP689660","node_attrs":{"div":560,"accession":"OP689660","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.14"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP689660/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI507"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","T607-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}}]}]},{"name":"NODE_0000215","node_attrs":{"div":558,"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G5595A","C191615T"],"OPG015":["Q188*"],"OPG015_dup":["Q188*"]},"labels":{"aa":"OPG015: Q188*; OPG015_dup: Q188*","clade":"B.1.8"}},"children":[{"name":"OP215224","node_attrs":{"div":558,"accession":"OP215224","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.8"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP215224/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI235"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000129","node_attrs":{"div":559,"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G161296A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP331337","node_attrs":{"div":559,"accession":"OP331337","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.8"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP331337/2022-06-29"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_UK_2022_9000183"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-29"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G902A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","C196308T"],"OPG001":["S225L"],"OPG001_dup":["S225L"]},"labels":{"aa":"OPG001: S225L; OPG001_dup: S225L"}}},{"name":"OP626129","node_attrs":{"div":560,"accession":"OP626129","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.8"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP626129/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI491"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C24929T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG040":["D184N"]},"labels":{"aa":"OPG040: D184N"}}},{"name":"OP555609","node_attrs":{"div":561,"accession":"OP555609","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.8"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555609/2022-08-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0538/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-23"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","G902A","C25269T","G25692A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C196308T"],"OPG001":["S225L"],"OPG001_dup":["S225L"]},"labels":{"aa":"OPG001: S225L; OPG001_dup: S225L"}}},{"name":"OR030928","node_attrs":{"div":560,"accession":"OR030928","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.8"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR030928/2022-07-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_17"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-19"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G902A","C68981T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C196308T"],"OPG001":["S225L"],"OPG001_dup":["S225L"],"OPG087":["S42L"]},"labels":{"aa":"OPG001: S225L; OPG001_dup: S225L; OPG087: S42L"}}},{"name":"OR449304","node_attrs":{"div":559,"accession":"OR449304","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.8"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OR449304/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI1018"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"NODE_0000130","node_attrs":{"div":562,"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G89716A","G128858A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C186220T"],"OPG110":["E29K"],"OPG210":["A1622V"]},"labels":{"aa":"OPG110: E29K; OPG210: A1622V"}},"children":[{"name":"OP594202","node_attrs":{"div":562,"accession":"OP594202","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.8"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP594202/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI438"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A613-","A614-","A615-","T179188-","A179189-"]}}},{"name":"OP863249","node_attrs":{"div":562,"accession":"OP863249","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.8"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP863249/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI599"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","T150567-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","G181052-"],"OPG209":["G179-"]},"labels":{"aa":"OPG209: G179-"}}}]},{"name":"NODE_0000131","node_attrs":{"div":562,"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C80545T","G102614A","C170573T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG103":["S182L"],"OPG122":["V63I"],"OPG198":["S179L"]},"labels":{"aa":"OPG103: S182L; OPG122: V63I; OPG198: S179L"}},"children":[{"name":"OR035714","node_attrs":{"div":562,"accession":"OR035714","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.8"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR035714/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_108"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T196712-","A196713-","T196714-"]}}},{"name":"OR086994","node_attrs":{"div":562,"accession":"OR086994","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.8"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR086994/2022-08-03"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_185/Belgium/2022"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-03"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000142","node_attrs":{"div":560,"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G78034A","C80111T"],"OPG099":["D124N"]},"labels":{"aa":"OPG099: D124N"}},"children":[{"name":"ON622718","node_attrs":{"div":561,"accession":"ON622718","author":{"author":"Martinez-Puchol,S.,Coello,A.,Bordoy,A.E.,Soler,L.,Panisello,D.,Gonzalez-Gomez,S.,Clara,G.,Paris de Leon,A.,Not,A.,Hernandez,A.,Bofill-Mas,S.,Saludes,V.,Blanco,I.,Martro,E.,Cardona,P.-J.","value":"Martinez-Puchol,S.,Coello,A.,Bordoy,A.E.,Soler,L.,Panisello,D.,Gonzalez-Gomez,S.,Clara,G.,Paris de Leon,A.,Not,A.,Hernandez,A.,Bofill-Mas,S.,Saludes,V.,Blanco,I.,Martro,E.,Cardona,P.-J."},"lineage":{"value":"B.1.8"},"country":{"value":"Spain"},"strain_display":{"value":"Spain/ON622718/2022-05-20"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/ES0001/HUGTiP/2022"},"institution":{"value":"Microbiology, Hospital Universitari Germans Trias i Pujol, Spain"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-20"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C14113-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T139150C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","-196615A","-196616A"],"OPG156":["Q87R"]},"labels":{"aa":"OPG156: Q87R"}}},{"name":"NODE_0000143","node_attrs":{"div":562,"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G22643A","G63811A"],"OPG038":["H173Y"]},"labels":{"aa":"OPG038: H173Y"}},"children":[{"name":"OP378705","node_attrs":{"div":562,"accession":"OP378705","author":{"author":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y.","value":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y."},"lineage":{"value":"B.1.8"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP378705/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_TX0011"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP480416","node_attrs":{"div":568,"accession":"OP480416","author":{"author":"Deanhardt,B.,Miller,M.,Wang,J.R.","value":"Deanhardt,B.,Miller,M.,Wang,J.R."},"lineage":{"value":"B.1.8"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP480416/2022-08-24"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMPXV/USA/NC-UNC-0017/2022"},"institution":{"value":"University of North Carolina at Chapel Hill, Department of Genetics"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-24"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G2079A","C12359T","A31053G","C89240T","G150404A","C173533A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C195131T"],"OPG002":["R225C"],"OPG002_dup":["R225C"],"OPG023":["R181Q"],"OPG047":["C48R"],"OPG109":["D70N"],"OPG176":["R199K"]},"labels":{"aa":"OPG002: R225C; OPG002_dup: R225C; OPG023: R181Q; OPG047: C48R; OPG109: D70N; OPG176: R199K"}}},{"name":"OP459214","node_attrs":{"div":562,"accession":"OP459214","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.8"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP459214/2022-08-30"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"ANT-LDSP-ANT-MPX-23631-L"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-30"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP642374","node_attrs":{"div":563,"accession":"OP642374","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.8"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP642374/2022-09-08"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"ANT-LDSP-ANT-MPX-24722-L"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-08"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G168759A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG195":["R177K"]},"labels":{"aa":"OPG195: R177K"}}},{"name":"OP604531","node_attrs":{"div":563,"accession":"OP604531","author":{"author":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Knipe,K.,Burroughs,S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Knipe,K.,Burroughs,S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y."},"lineage":{"value":"B.1.8"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP604531/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_FL0020"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C181695T"],"OPG210":["P114S"]},"labels":{"aa":"OPG210: P114S"}}},{"name":"OQ320513","node_attrs":{"div":566,"accession":"OQ320513","author":{"author":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y.","value":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y."},"lineage":{"value":"B.1.8"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ320513/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_FL0009"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G4038A","A39081T","C67289T","G73790A","T133099-","A173284-","T173285-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C193172T"],"OPG057":["I372N"],"OPG085":["E415K"],"OPG094":["G4E"]},"labels":{"aa":"OPG057: I372N; OPG085: E415K; OPG094: G4E"}}},{"name":"OR759149","node_attrs":{"div":566,"accession":"OR759149","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.8"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OR759149/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/Canada/ON-PHOL055/2022"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C8555T","G95862A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168089T","G181674A","-196615A"],"OPG116":["A168T"],"OPG210":["E107K"]},"labels":{"aa":"OPG116: A168T; OPG210: E107K"}}},{"name":"NODE_0000144","node_attrs":{"div":563,"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T119985C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP415254","node_attrs":{"div":564,"accession":"OP415254","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.8"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP415254/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX_imBNaw_9000300"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G189258A"]}}},{"name":"OP681775","node_attrs":{"div":563,"accession":"OP681775","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.8"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP681775/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-098497/2022"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}}]}]}]}]},{"name":"NODE_0000182","node_attrs":{"div":559,"lineage":{"value":"B.1.10"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C89906T","G94798A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179217C","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG110":["S92F"],"OPG115":["E47K"]},"labels":{"aa":"OPG110: S92F; OPG115: E47K","clade":"B.1.10"}},"children":[{"name":"ON720848","node_attrs":{"div":562,"accession":"ON720848","author":{"author":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"lineage":{"value":"B.1.10"},"country":{"value":"Spain"},"strain_display":{"value":"Spain/ON720848/2022-05-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MpxV/Spain/MD-HGUGM-6513479/2022"},"institution":{"value":"Microbial Genomics, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-27"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A327-","T605-","T606-","A1697-","T4296-","T6587-","T6588-","T7253-","G7724-","T8017-","A8036-","T8499-","T9509-","A9869-","T10502-","A10914-","T11188-","C11749-","T11761-","T12121-","A15754-","A17087-","T18861-","A19360-","T20663-","A21081-","T21975-","T24678-","T25853-","T26099-","C27002-","A27114-","C27799-","A28531-","A28532-","T32194-","T33414-","G35949-","T37982-","T39131-","T39866-","T41744-","T42990-","C43014-","G43200-","A43443-","T44120-","T44738-","G46762-","T48675-","A49134-","G49833-","A51022-","A52765-","A54968-","A55124-","T55560-","T56040-","T57075-","A57277-","A58650-","T61749-","A62041-","T63628-","A64728-","A64935-","A65535-","A65967-","T66783-","A66843-","A67164-","C68466-","T68481-","C68899-","G69145-","A69744-","T69768-","A71254-","G71359-","T75833-","A76072-","T76084-","T76085-","A76153-","A76154-","A76890-","A77260-","T77803-","T78062-","A79042-","A79181-","G79217-","C79533T","A79787-","G80950-","C82482-","T84846-","T88095-","T88836-","T88941-","A89106-","T90646-","T91129-","T91370-","A91583-","A91705-","T94795-","A95341-","A95574-","G95742-","G95818-","A97351-","A97480-","A97501-","A97699-","A98683-","T101452-","G101515-","T102437-","T103367-","T103368-","T104279-","T105360-","T106596-","T108598-","A113921-","T113951-","C114431-","T114518-","T114755-","T115127-","G115801-","A116014-","C116494-","T116963-","T121121-","T121122-","G121269-","C121546-","T124022-","T124751-","A125249-","A126568-","T126682-","A126715-","A127250-","A127754-","A132023-","A132024-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133639-","T136780-","T137886-","A143045-","G143363-","T143478-","A144230-","T146131-","A148000-","A149727-","A150340-","T150538-","T150539-","A150635-","T150864-","A151490-","A151508-","G151545-","A152676-","T152686-","A153358-","A153424-","A153517-","T154862-","T155424-","C156607-","C156608-","A157997-","T163498-","T163597-","A163957-","A165461-","A166740-","G167640-","A167967-","T168120-","A170728-","T170758-","T170903-","T170904-","T172087A","A172092-","T172667-","G179036-","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","A179551-","A179950-","T180905-","G181052-","A181253-","C183534-","A183780-","T187080A","A187083-","A190935-","A191015-","G191519-","A196613-","A196614-","T196888-","T197183-"],"OPG015_dup":["G156-"],"OPG016":["T176-"],"OPG019":["G49-"],"OPG021":["N95-"],"OPG023":["G385-"],"OPG043":["G53-"],"OPG044":["M148-"],"OPG066":["P223-"],"OPG068":["L159-","D545-"],"OPG070":["N145-"],"OPG074":["K523-"],"OPG084":["K3-","K272-","R416-"],"OPG085":["F457-"],"OPG087":["L15-","G97-"],"OPG090":["K26-"],"OPG096":["L83-"],"OPG098":["S121-"],"OPG099":["F47-"],"OPG100":["F19-"],"OPG102":["K33-"],"OPG104":["P24-"],"OPG109":["K206-"],"OPG111":["F128-"],"OPG112":["S42-"],"OPG115":["S46-"],"OPG116":["K72-"],"OPG117":["K435-","N478-","R551-"],"OPG118":["I80-"],"OPG122":["Y4-"],"OPG123":["K569-"],"OPG133":["K394-"],"OPG134":["E18-","P249-"],"OPG139":["P34-"],"OPG145":["F26-","F269-","K435-"],"OPG148":["I195-","F233-"],"OPG149":["K19-"],"OPG151":["K1034-"],"OPG164":["R90-"],"OPG165":["M239-"],"OPG172":["I192-"],"OPG175":["N96-"],"OPG176":["K178-"],"OPG178":["D13-"],"OPG180":["K223-","K276-"],"OPG181":["F151-"],"OPG189":["L56-","K209-"],"OPG190":["N114-"],"OPG192":["K4-"],"OPG193":["G103-","F263-"],"OPG198":["K231-"],"OPG208":["I96-"],"OPG209":["L130-"],"OPG210":["P727-"]},"labels":{"aa":"OPG015_dup: G156-; OPG016: T176-; OPG019: G49-; OPG021: N95-; OPG023: G385-; OPG043: G53-; OPG044: M148-; OPG066: P223-; OPG068: L159-, D545-; OPG070: N145-; OPG074: K523-; OPG084: K3-, K272-, R416-; OPG085: F457-; OPG087: L15-, G97-; OPG090: K26-; OPG096: L83-; OPG098: S121-; OPG099: F47-; OPG100: F19-; OPG102: K33-; OPG104: P24-; OPG109: K206-; OPG111: F128-; OPG112: S42-; OPG115: S46-; OPG116: K72-; OPG117: K435-, N478-, R551-; OPG118: I80-; OPG122: Y4-; OPG123: K569-; OPG133: K394-; OPG134: E18-, P249-; OPG139: P34-; OPG145: F26-, F269-, K435-; OPG148: I195-, F233-; OPG149: K19-; OPG151: K1034-; OPG164: R90-; OPG165: M239-; OPG172: I192-; OPG175: N96-; OPG176: K178-; OPG178: D13-; OPG180: K223-, K276-; OPG181: F151-; OPG189: L56-, K209-; OPG190: N114-; OPG192: K4-; OPG193: G103-, F263-; OPG198: K231-; OPG208: I96-; OPG209: L130-; OPG210: P727-"}}},{"name":"OP245334","node_attrs":{"div":561,"accession":"OP245334","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.10"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP245334/2022-07-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX/PT0081/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-23"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-609T","G610-","T611-","C120237T","G126047A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","C179217-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A196619-","T196620-"],"OPG148":["R21K"]},"labels":{"aa":"OPG148: R21K"}}},{"name":"OP205110","node_attrs":{"div":559,"accession":"OP205110","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.10"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP205110/2022-06-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_UK_2022_9000147"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-14"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T"]}}},{"name":"OP205091","node_attrs":{"div":559,"accession":"OP205091","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.10"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP205091/2022-06-13"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_UK_2022_9000103"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-13"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T"]}}},{"name":"OP450985","node_attrs":{"div":559,"accession":"OP450985","author":{"author":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y.","value":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y."},"lineage":{"value":"B.1.10"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP450985/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_TX0019"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","A136552-","T136553-","C136554-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","C179217-","-196615A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP642391","node_attrs":{"div":559,"accession":"OP642391","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP642391/2022-09-02"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"ANT-LDSP-ANT-MPX-24446-E"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-02"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OQ261696","node_attrs":{"div":564,"accession":"OQ261696","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OQ261696/2022-10-13"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"ANT-LDSP-ANT-MPX-28205C"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-13"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C9389T","C13399T","G17339A","C49265T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","A185557C","C190859T","T196852-","G196853-","T196854-"],"OPG210":["K1401T"]},"labels":{"aa":"OPG210: K1401T"}}},{"name":"OQ581847","node_attrs":{"div":572,"accession":"OQ581847","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"lineage":{"value":"B.1.10"},"country":{"value":"Spain"},"strain_display":{"value":"Spain/OQ581847/2022-07-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0005b/2022"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A43453G","A66769C","T88735A","G90070A","C101656T","G104325A","C121681T","G127869A","G132490A","T133095A","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T139779C","G140866T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C151204T","T176743A","-179218A","-179219T","-179220T"],"OPG063":["L79P"],"OPG085":["V588G"],"OPG109":["E238V"],"OPG110":["D147N"],"OPG123":["A249V"],"OPG150":["G31R"],"OPG160":["S70Y"],"OPG205":["L363*"]},"labels":{"aa":"OPG063: L79P; OPG085: V588G; OPG109: E238V; OPG110: D147N; OPG123: A249V; OPG150: G31R; OPG160: S70Y; OPG205: L363*"}}},{"name":"OR264420","node_attrs":{"div":560,"accession":"OR264420","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.10"},"country":{"value":"Australia"},"strain_display":{"value":"Australia/OR264420/2022-07-10"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"},"strain":{"value":"45_B"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-10"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G63147A","-179218A","-179219T","-179220T","C179226T","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-"]}}},{"name":"NODE_0000183","node_attrs":{"div":560,"lineage":{"value":"B.1.10"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C150831T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-"]}},"children":[{"name":"ON959143","node_attrs":{"div":561,"accession":"ON959143","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O."},"lineage":{"value":"B.1.10"},"country":{"value":"Finland"},"strain_display":{"value":"Finland/ON959143/2022-06-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX-96/Finland/2022"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-16"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","C188491T"]}}},{"name":"OP382489","node_attrs":{"div":561,"accession":"OP382489","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1.10"},"country":{"value":"France"},"strain_display":{"value":"France/OP382489/2022-07-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMPXV-IHU00012"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-19"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G109437A","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G150603-","A150604-","T150605-","A150606-","T150607-","G150608-","A150609-","T150610-","G150611-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T"],"OPG129":["S523L"],"OPG153":["D384-","D385-"]},"labels":{"aa":"OPG129: S523L; OPG153: D384-, D385-"}}},{"name":"OP879740","node_attrs":{"div":560,"accession":"OP879740","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"lineage":{"value":"B.1.10"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP879740/2022-07-06"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"NJ-MPXV-022"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-06"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","C179217-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}}]},{"name":"NODE_0000184","node_attrs":{"div":561,"lineage":{"value":"B.1.10"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C33103T","C45605T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","C179217-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG049":["E17K"]},"labels":{"aa":"OPG049: E17K"}},"children":[{"name":"OP215226","node_attrs":{"div":562,"accession":"OP215226","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.10"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP215226/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI241"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G47702A"]}}},{"name":"OP594193","node_attrs":{"div":561,"accession":"OP594193","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.10"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP594193/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI429"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OQ773504","node_attrs":{"div":561,"accession":"OQ773504","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.10"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ773504/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI885"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A41660-","A41661-","T41662-","T41663-","T41664-","G41665-","T41666-","T41667-","T41668-","T41669-","A41670-","C41671-","T41672-","C41673-","T41674-","A41675-","T41676-","A41677-","G150551-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG061":["Y70-","R71-","V72-","K73-","Q74-","I75-"]},"labels":{"aa":"OPG061: Y70-, R71-, V72-, K73-, Q74-, I75-"}}}]},{"name":"NODE_0000185","node_attrs":{"div":561,"lineage":{"value":"B.1.10"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C20879T","C60094T"],"OPG036":["M62I"],"OPG080":["R642K"]},"labels":{"aa":"OPG036: M62I; OPG080: R642K"}},"children":[{"name":"OP415264","node_attrs":{"div":562,"accession":"OP415264","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.10"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP415264/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX_Tga3e9_9000325"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G86904A","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T"]}}},{"name":"OR035722","node_attrs":{"div":562,"accession":"OR035722","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.10"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR035722/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_116"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T133099-","G149818A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","T196712-","A196713-","T196714-"],"OPG176":["D4N"]},"labels":{"aa":"OPG176: D4N"}}},{"name":"OR464215","node_attrs":{"div":561,"accession":"OR464215","author":{"author":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y.","value":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y."},"lineage":{"value":"B.1.10"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR464215/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_DC0006"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","C179217-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}}]},{"name":"NODE_0000186","node_attrs":{"div":560,"lineage":{"value":"B.1.10"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G50672A","-179194A","-179195T","C179265-","A179266-","T179267-"],"OPG070":["R28K"]},"labels":{"aa":"OPG070: R28K"}},"children":[{"name":"OP689664","node_attrs":{"div":562,"accession":"OP689664","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.10"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP689664/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI511"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C13624T","C43472T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179217-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG063":["E73K"]},"labels":{"aa":"OPG063: E73K"}}},{"name":"OQ696103","node_attrs":{"div":565,"accession":"OQ696103","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OQ696103/2022-11-22"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"ANT-LDSP-ANT-MPX-31501C"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-22"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G32863A","G45416A","C72770T","C123118T","C148771T","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG092":["E60K"],"OPG174":["D209N"]},"labels":{"aa":"OPG092: E60K; OPG174: D209N"}}},{"name":"NODE_0000187","node_attrs":{"div":562,"lineage":{"value":"B.1.10"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C49265T","C100007T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179265C","-179266A","-179267T"],"OPG118":["S521F"]},"labels":{"aa":"OPG118: S521F"}},"children":[{"name":"OP536764","node_attrs":{"div":562,"accession":"OP536764","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.10"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP536764/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"9000385"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"]}}},{"name":"OP477453","node_attrs":{"div":562,"accession":"OP477453","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP477453/2022-08-23"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"ANT-LDSP-ANT-MPX-23188-L"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-23"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}}]}]}]},{"name":"NODE_0000188","node_attrs":{"div":558,"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G1302A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C182950T"],"OPG001":["L92F"],"OPG210":["S532L"]},"labels":{"aa":"OPG001: L92F; OPG210: S532L","clade":"B.1.12"}},"children":[{"name":"OQ773485","node_attrs":{"div":558,"accession":"OQ773485","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.12"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ773485/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI866"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150563-","T150564-","G150565-","A150566-","T150567-","-179189A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"]}}},{"name":"NODE_0000189","node_attrs":{"div":559,"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G78328A","C195908T"],"OPG001_dup":["L92F"]},"labels":{"aa":"OPG001_dup: L92F"}},"children":[{"name":"OP524001","node_attrs":{"div":559,"accession":"OP524001","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.12"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP524001/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI399"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000190","node_attrs":{"div":560,"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C57550T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP415207","node_attrs":{"div":560,"accession":"OP415207","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.12"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP415207/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX_BhVKjm_9000233"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OP415206","node_attrs":{"div":560,"accession":"OP415206","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.12"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP415206/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX_BhVKjm_9000232"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000191","node_attrs":{"div":559,"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A1302G","G111084A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"],"OPG001":["F92L"]},"labels":{"aa":"OPG001: F92L"}},"children":[{"name":"OP013003","node_attrs":{"div":559,"accession":"OP013003","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I."},"lineage":{"value":"B.1.12"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OP013003/2022-05-31"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/CAN/UN-NML-3276/2022"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-31"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"ON880548","node_attrs":{"div":559,"accession":"ON880548","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.12"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/ON880548/2022-06-03"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/CAN/UN-NML-3448/2022"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-03"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OQ121959","node_attrs":{"div":567,"accession":"OQ121959","author":{"author":"Barbian,H.,Green,S.,Kunstman,K.,Araujo Perez,F.,Bobrovska,S.,Hayden,M.,Moore,N.","value":"Barbian,H.,Green,S.,Kunstman,K.,Araujo Perez,F.,Bobrovska,S.,Hayden,M.,Moore,N."},"lineage":{"value":"B.1.12"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ121959/2022-10-18"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/Human/USA/IL-RIPHL-MPXV_10015/2022"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-18"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","G4859A","C24077T","C24231T","G67582A","C88319T","G97405A","C101656T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G165506A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C192351T","A196614-"],"OPG015":["S433L"],"OPG015_dup":["S433L"],"OPG085":["S317L"],"OPG109":["A377T"],"OPG117":["E453K"],"OPG190":["E129K"]},"labels":{"aa":"OPG015: S433L; OPG015_dup: S433L; OPG085: S317L; OPG109: A377T; OPG117: E453K; OPG190: E129K"}}},{"name":"NODE_0000192","node_attrs":{"div":560,"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G121510A"]}},"children":[{"name":"ON880540","node_attrs":{"div":560,"accession":"ON880540","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.12"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/ON880540/2022-06-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/CAN/UN-NML-3342/2022"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OR759170","node_attrs":{"div":565,"accession":"OR759170","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.12"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OR759170/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/Canada/ON-PHOL082/2022"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","G10060A","G37022A","C132410T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G154793A","C180055T","-196615A"],"OPG055":["S21F"],"OPG181":["D128N"]},"labels":{"aa":"OPG055: S21F; OPG181: D128N"}}}]},{"name":"NODE_0000193","node_attrs":{"div":561,"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G98233A","G98455A"],"OPG117":["D729N"]},"labels":{"aa":"OPG117: D729N"}},"children":[{"name":"ON880413","node_attrs":{"div":562,"accession":"ON880413","author":{"author":"Coletti,T.M.,Ghilardi,F.,khan,M.J.,Claro,I.M.,Valenca,I.N.,Faria,N.R.,Sabino,E.C.","value":"Coletti,T.M.,Ghilardi,F.,khan,M.J.,Claro,I.M.,Valenca,I.N.,Faria,N.R.,Sabino,E.C."},"lineage":{"value":"B.1.12"},"country":{"value":"Brazil"},"strain_display":{"value":"Brazil/ON880413/2022-06-14"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"MPX/BR0002/2022"},"institution":{"value":"Imperial College London, School of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-14"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C76334T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG097":["R181K"]},"labels":{"aa":"OPG097: R181K"}}},{"name":"NODE_0000194","node_attrs":{"div":562,"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G98456A","-179172C","-179173A","-179174T","-179176A","-179177T","-179178A","-179179T","-179180A"],"OPG118":["G4K"]},"labels":{"aa":"OPG118: G4K"}},"children":[{"name":"OP270022","node_attrs":{"div":565,"accession":"OP270022","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.12"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OP270022/2022-07-04"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/CAN/UN-NML-3972/2022"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-04"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","G3361A","C152970T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G181349A","C193849T"],"OPG003":["S416L"],"OPG003_dup":["S416L"]},"labels":{"aa":"OPG003: S416L; OPG003_dup: S416L"}}},{"name":"OP378701","node_attrs":{"div":563,"accession":"OP378701","author":{"author":"Gigante,C.M.,Hughes,S.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"lineage":{"value":"B.1.12"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP378701/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_NY0028"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G4691-","A4692-","C4693-","T4694-","T4695-","A4696-","A4697-","C4698-","T4699-","A4700-","A4701-","C4702-","T4703-","T4704-","A4705-","T4706-","G4707-","A4708-","C4709-","T4710-","T4711-","A4712-","A4713-","C4714-","T4715-","A4716-","A4717-","C4718-","T4719-","T4720-","A4721-","T4722-","C40966T","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","A179176-","T179177-","A179178-","T179179-","A179180-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"],"OPG060":["D73N"]},"labels":{"aa":"OPG060: D73N"}}},{"name":"OP881955","node_attrs":{"div":565,"accession":"OP881955","author":{"author":"Gigante,C.,Griffin-Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Crain,J.,Li,Y.","value":"Gigante,C.,Griffin-Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Crain,J.,Li,Y."},"lineage":{"value":"B.1.12"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP881955/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_VA0010"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G95762A","C107442T","C149304T","A173316-","T173317-","-179175T"],"OPG174":["R31K"]},"labels":{"aa":"OPG174: R31K"}}},{"name":"OR209309","node_attrs":{"div":565,"accession":"OR209309","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"lineage":{"value":"B.1.12"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR209309/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_TN0019"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C93601T","C94418T","T133099-","T133100-","C136029T","-179175T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["A624V"],"OPG114":["E84K"]},"labels":{"aa":"OPG113: A624V; OPG114: E84K"}}},{"name":"OR464195","node_attrs":{"div":563,"accession":"OR464195","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"lineage":{"value":"B.1.12"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR464195/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_NY0047"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T67849G","-179175T"],"OPG085":["N228T"]},"labels":{"aa":"OPG085: N228T"}}},{"name":"NODE_0000195","node_attrs":{"div":563,"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G153910A","C179172-","A179173-","T179174-"],"OPG180":["E407K"]},"labels":{"aa":"OPG180: E407K"}},"children":[{"name":"OR026631","node_attrs":{"div":565,"accession":"OR026631","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"lineage":{"value":"B.1.12"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR026631/2022-09-06"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200369/2022"},"institution":{"value":"Utah Public Health Laboratory, Utah Public Health Laboratory Infectious Disease submission group"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-06"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G11924A","A37326C"],"OPG023":["S326L"],"OPG056":["I570R"]},"labels":{"aa":"OPG023: S326L; OPG056: I570R"}}},{"name":"OQ918701","node_attrs":{"div":568,"accession":"OQ918701","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.12"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ918701/2023-02-10"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00490/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-10"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C21910T","G28483A","G39552A","A57421-","C57422-","A57423-","A57424-","A57425-","A57426-","A57427-","G57428-","G57429-","A57430-","C57431-","A57432-","T57433-","G57434-","T57435-","A57436-","A57437-","A57438-","C57439-","T57440-","T57441-","G132490A","C150443T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG037":["R175K"],"OPG057":["S215F"],"OPG075":["K20-","F21-","T22-","C23-","P24-","F25-","C26-"],"OPG176":["T212I"]},"labels":{"aa":"OPG037: R175K; OPG057: S215F; OPG075: K20-, F21-, T22-, C23-, P24-, F25-, C26-; OPG176: T212I"}}},{"name":"OR759180","node_attrs":{"div":567,"accession":"OR759180","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.12"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OR759180/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/Canada/ON-PHOL092/2022"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","C16209T","C24208T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179176-","T179177-","A179178-","T179179-","A179180-","G182088A","G182189A","A196614-"],"OPG027":["E57K"],"OPG210":["E245K"]},"labels":{"aa":"OPG027: E57K; OPG210: E245K"}}}]},{"name":"NODE_0000196","node_attrs":{"div":563,"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C24231T","-179175T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","T179244-"]}},"children":[{"name":"OP390179","node_attrs":{"div":563,"accession":"OP390179","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.12"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP390179/2022-08-24"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"BOL-UNIMOL-MPX-293015-L"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-24"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP382485","node_attrs":{"div":564,"accession":"OP382485","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1.12"},"country":{"value":"France"},"strain_display":{"value":"France/OP382485/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMPXV-IHU00008"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G184227A"],"OPG210":["D958N"]},"labels":{"aa":"OPG210: D958N"}}},{"name":"OR095032","node_attrs":{"div":564,"accession":"OR095032","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.12"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR095032/2022-08-08"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_214/Belgium/2022"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-08"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G61102A","T179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-179244T"],"OPG080":["S306F"]},"labels":{"aa":"OPG080: S306F"}}},{"name":"NODE_0000197","node_attrs":{"div":564,"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G23457A"],"OPG039":["S221F"]},"labels":{"aa":"OPG039: S221F"}},"children":[{"name":"OP415236","node_attrs":{"div":564,"accession":"OP415236","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.12"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP415236/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX_ilzdZn_9000269"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A190409-","A190410-","T190411-","G190412-","G190413-","A190414-","T190415-","T190416-","C190417-","G190418-","C190419-","G190420-","T190421-","A190422-","T190423-","A190424-","G190425-","C190426-"]}}},{"name":"OR264365","node_attrs":{"div":564,"accession":"OR264365","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.12"},"country":{"value":"Australia"},"strain_display":{"value":"Australia/OR264365/2022-07-18"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"},"strain":{"value":"12_A"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-18"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}}]}]}]}]}]}]},{"name":"NODE_0000198","node_attrs":{"div":558,"lineage":{"value":"B.1.5"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C70780T"]},"labels":{"clade":"B.1.5"}},"children":[{"name":"OP150925","node_attrs":{"div":558,"accession":"OP150925","author":{"author":"Gigante,C.,Xia,D.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y.","value":"Gigante,C.,Xia,D.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y."},"lineage":{"value":"B.1.5"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP150925/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_GA001"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON959170","node_attrs":{"div":559,"accession":"ON959170","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/ON959170/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI156"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G26136A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG042":["S321F"]},"labels":{"aa":"OPG042: S321F"}}},{"name":"ON959175","node_attrs":{"div":558,"accession":"ON959175","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/ON959175/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI162"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON918656","node_attrs":{"div":562,"accession":"ON918656","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"B.1.5"},"country":{"value":"Taiwan"},"strain_display":{"value":"Taiwan/ON918656/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MPXV/human/Taiwan/110-231642/2022"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C28702T","T34793C","T50861C","C51777T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG054":["T402A"],"OPG070":["V91A"],"OPG071":["E888K"]},"labels":{"aa":"OPG054: T402A; OPG070: V91A; OPG071: E888K"}}},{"name":"ON843165","node_attrs":{"div":558,"accession":"ON843165","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.5"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/ON843165/2022-05-24"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0033/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-24"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON792322","node_attrs":{"div":558,"accession":"ON792322","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"lineage":{"value":"B.1.5"},"country":{"value":"Switzerland"},"strain_display":{"value":"Switzerland/ON792322/2022-06-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba64538/2022"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-02"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON780017","node_attrs":{"div":558,"accession":"ON780017","author":{"author":"Gramigna,G.,Giombini,E.,Gruber,C.E.M.,Rueca,M.,Carletti,F.,Cicalini,S.,Lapa,D.,Puro,V.,Marani,A.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Rivano Capparuccia,M.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F.","value":"Gramigna,G.,Giombini,E.,Gruber,C.E.M.,Rueca,M.,Carletti,F.,Cicalini,S.,Lapa,D.,Puro,V.,Marani,A.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Rivano Capparuccia,M.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F."},"lineage":{"value":"B.1.5"},"country":{"value":"Italy"},"strain_display":{"value":"Italy/ON780017/2022-05-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"INMI-Pt4"},"institution":{"value":"INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-21"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A"]}}},{"name":"OP450990","node_attrs":{"div":561,"accession":"OP450990","author":{"author":"Gigante,C.M.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y.","value":"Gigante,C.M.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y."},"lineage":{"value":"B.1.5"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP450990/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_NV0001"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G75554A","G147179A","G159373A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG185":["E153K"]},"labels":{"aa":"OPG185: E153K"}}},{"name":"OP414288","node_attrs":{"div":558,"accession":"OP414288","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.5"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP414288/2022-06-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0244/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-21"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"]}}},{"name":"OP555486","node_attrs":{"div":558,"accession":"OP555486","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.5"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555486/2022-07-11"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0390/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-11"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179175T","T179244-","C179245-","G179246-","T179247-"]}}},{"name":"OP523979","node_attrs":{"div":559,"accession":"OP523979","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP523979/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI377"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G174625A"],"OPG204":["E32K"]},"labels":{"aa":"OPG204: E32K"}}},{"name":"OP555650","node_attrs":{"div":560,"accession":"OP555650","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.5"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555650/2022-09-10"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0579/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-10"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C41022T","A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159001A"],"OPG060":["R54K"],"OPG153":["D385-"],"OPG185":["D29N"]},"labels":{"aa":"OPG060: R54K; OPG153: D385-; OPG185: D29N"}}},{"name":"OP555598","node_attrs":{"div":566,"accession":"OP555598","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.5"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555598/2022-08-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0527/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-19"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G5876A","C87141T","C126707T","C128030T","C128417T","C133867T","C134247T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C187128T","C191334T"],"OPG015":["S94F"],"OPG015_dup":["S94F"],"OPG148":["S241L"]},"labels":{"aa":"OPG015: S94F; OPG015_dup: S94F; OPG148: S241L"}}},{"name":"OQ274882","node_attrs":{"div":558,"accession":"OQ274882","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ274882/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI663"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-"]}}},{"name":"OQ547766","node_attrs":{"div":558,"accession":"OQ547766","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ547766/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI739"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"NODE_0000199","node_attrs":{"div":562,"lineage":{"value":"B.1.5"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C30283T","C37054T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","T179244-","G179589A","G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N"}},"children":[{"name":"OR264398","node_attrs":{"div":562,"accession":"OR264398","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.5"},"country":{"value":"Australia"},"strain_display":{"value":"Australia/OR264398/2022-06-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"},"strain":{"value":"34_B"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-30"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OR264397","node_attrs":{"div":562,"accession":"OR264397","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.5"},"country":{"value":"Australia"},"strain_display":{"value":"Australia/OR264397/2022-08-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"},"strain":{"value":"34_A"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-16"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-"]}}}]},{"name":"NODE_0000200","node_attrs":{"div":559,"lineage":{"value":"B.1.5"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C160426T"]}},"children":[{"name":"OQ503754","node_attrs":{"div":563,"accession":"OQ503754","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.5"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ503754/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-119069/2022"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T10449-","A10450-","G10451-","A10452-","T10453-","G75332A","T124690C","C144211T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G185394A"],"OPG095":["R177K"],"OPG210":["E1347K"]},"labels":{"aa":"OPG095: R177K; OPG210: E1347K"}}},{"name":"NODE_0000201","node_attrs":{"div":561,"lineage":{"value":"B.1.5"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G111379A","G165326A"],"OPG130":["S175L"],"OPG190":["E69K"]},"labels":{"aa":"OPG130: S175L; OPG190: E69K"}},"children":[{"name":"OP351284","node_attrs":{"div":563,"accession":"OP351284","author":{"author":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T.","value":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T."},"lineage":{"value":"B.1.5"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP351284/2022-07-22"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV22/human/USA-OK-69"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-22"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G22207A","C120671T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616T","-196617A"],"OPG037":["S76F"]},"labels":{"aa":"OPG037: S76F"}}},{"name":"OP879727","node_attrs":{"div":561,"accession":"OP879727","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"lineage":{"value":"B.1.5"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP879727/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"NJ-MPXV-006-rpt1"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ721933","node_attrs":{"div":562,"accession":"OQ721933","author":{"author":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y.","value":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y."},"lineage":{"value":"B.1.5"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ721933/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_OH0005"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G48045A","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","G173318-","G173319-","G173320-","C173321-","A173322-","A173323-","A173324-","A173325-","C173326-","A173327-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"]}}}]}]},{"name":"NODE_0000202","node_attrs":{"div":559,"lineage":{"value":"B.1.5"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C44333T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG064":["M522I"]},"labels":{"aa":"OPG064: M522I"}},"children":[{"name":"OP415189","node_attrs":{"div":559,"accession":"OP415189","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.5"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP415189/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX_luLfgA_9000208"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OR035702","node_attrs":{"div":563,"accession":"OR035702","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.5"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR035702/2022-05-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_96"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-30"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C29315T","C60396T","G149807A","C161572T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG046":["D139N"]},"labels":{"aa":"OPG046: D139N"}}},{"name":"OR035675","node_attrs":{"div":560,"accession":"OR035675","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.5"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR035675/2022-06-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_69"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-30"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G161488A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OR449647","node_attrs":{"div":560,"accession":"OR449647","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OR449647/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI933"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G149300A","G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"NODE_0000203","node_attrs":{"div":560,"lineage":{"value":"B.1.5"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G93512T","-179195T","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T"],"OPG113":["K594N"]},"labels":{"aa":"OPG113: K594N"}},"children":[{"name":"OP358276","node_attrs":{"div":563,"accession":"OP358276","author":{"author":"Tramuto,F.","value":"Tramuto,F."},"lineage":{"value":"B.1.5"},"country":{"value":"Italy"},"strain_display":{"value":"Italy/OP358276/2022-08-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"SIC-AOUP-UNIPA_VL_9aug"},"institution":{"value":"University of Palermo, Department of Health Promotion Sciences Maternal and Infant Care, Internal Medicine and Medical Specialties \"G. D'Alessandro\"\"\""},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-09"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C33103T","C114490T","C133295T","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-"],"OPG049":["E17K"],"OPG133":["D403N"]},"labels":{"aa":"OPG049: E17K; OPG133: D403N"}}},{"name":"OP536772","node_attrs":{"div":562,"accession":"OP536772","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.5"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP536772/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"9000394"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C756T","G2898A","G3477A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C193733T","C194312T","G196454A"]}}}]}]}]},{"name":"NODE_0000204","node_attrs":{"div":558,"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N","clade":"B.1.2"}},"children":[{"name":"OP150927","node_attrs":{"div":558,"accession":"OP150927","author":{"author":"Gigante,C.,Pavlick,J.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y.","value":"Gigante,C.,Pavlick,J.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y."},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP150927/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_WA001"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON929079","node_attrs":{"div":558,"accession":"ON929079","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/ON929079/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI124"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP415193","node_attrs":{"div":558,"accession":"OP415193","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP415193/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX_gOirGi_9000215"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP378702","node_attrs":{"div":560,"accession":"OP378702","author":{"author":"Gigante,C.M.,Johnson,S.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Riner,D.,Li,Y.","value":"Gigante,C.M.,Johnson,S.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Riner,D.,Li,Y."},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP378702/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_MI0001"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G4691-","A4692-","C4693-","T4694-","T4695-","A4696-","A4697-","C4698-","T4699-","A4700-","A4701-","C4702-","T4703-","T4704-","A4705-","T4706-","G4707-","A4708-","C4709-","T4710-","T4711-","A4712-","A4713-","C4714-","T4715-","A4716-","A4717-","C4718-","T4719-","T4720-","A4721-","T4722-","G5375A","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C184829T","C191835T","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"],"OPG015":["A261V"],"OPG015_dup":["A261V"]},"labels":{"aa":"OPG015: A261V; OPG015_dup: A261V"}}},{"name":"OQ274892","node_attrs":{"div":558,"accession":"OQ274892","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ274892/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI673"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-"]}}},{"name":"OQ427136","node_attrs":{"div":561,"accession":"OQ427136","author":{"author":"Gigante,C.,Steidley,B.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Davizon,E.,Li,Y.","value":"Gigante,C.,Steidley,B.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Davizon,E.,Li,Y."},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ427136/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_CO0005"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C28321T","C94102T","A121162G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A"],"OPG113":["T791I"]},"labels":{"aa":"OPG113: T791I"}}},{"name":"NODE_0000205","node_attrs":{"div":559,"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G143789A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG165":["D92N"]},"labels":{"aa":"OPG165: D92N"}},"children":[{"name":"OP205087","node_attrs":{"div":560,"accession":"OP205087","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP205087/2022-06-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_UK_2022_9000099"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-09"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G61253A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG080":["R256C"]},"labels":{"aa":"OPG080: R256C"}}},{"name":"NODE_0000206","node_attrs":{"div":560,"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C20992T","-179194A","-179195T"],"OPG036":["D25N"]},"labels":{"aa":"OPG036: D25N"}},"children":[{"name":"NODE_0000207","node_attrs":{"div":561,"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C29229T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG045":["D12N"]},"labels":{"aa":"OPG045: D12N"}},"children":[{"name":"OP536807","node_attrs":{"div":566,"accession":"OP536807","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP536807/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"9000438"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G10475A","G23462A","C57492T","G73939A","C171808T"],"OPG075":["E3K"],"OPG094":["D54N"],"OPG199":["S274L"]},"labels":{"aa":"OPG075: E3K; OPG094: D54N; OPG199: S274L"}}},{"name":"OP536768","node_attrs":{"div":562,"accession":"OP536768","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP536768/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"9000390"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G165371A"],"OPG190":["E84K"]},"labels":{"aa":"OPG190: E84K"}}}]},{"name":"NODE_0000208","node_attrs":{"div":561,"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C147168T"],"OPG171":["L61F"]},"labels":{"aa":"OPG171: L61F"}},"children":[{"name":"OP279039","node_attrs":{"div":561,"accession":"OP279039","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.2"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OP279039/2022-06-28"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/CAN/UN-NML-4117/2022"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-28"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179208C","-179209A","-179210T","-179211T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP215208","node_attrs":{"div":561,"accession":"OP215208","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP215208/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI196"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"]}}},{"name":"OQ773457","node_attrs":{"div":561,"accession":"OQ773457","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ773457/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI838"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OR264416","node_attrs":{"div":561,"accession":"OR264416","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.2"},"country":{"value":"Australia"},"strain_display":{"value":"Australia/OR264416/2022-06-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"},"strain":{"value":"42_G"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-22"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226T","T179244-"]}}}]}]}]},{"name":"NODE_0000209","node_attrs":{"div":559,"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150590G","-150593G","-150594G","-150599G","-150602G","C188391T"]}},"children":[{"name":"OP205083","node_attrs":{"div":559,"accession":"OP205083","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP205083/2022-05-25"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_UK_2022_9000092"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-25"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP539917","node_attrs":{"div":560,"accession":"OP539917","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP539917/2022-09-09"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00132/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-09"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","G39312T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T196712-","A196713-","T196714-"],"OPG057":["A295E"]},"labels":{"aa":"OPG057: A295E"}}},{"name":"OP523982","node_attrs":{"div":559,"accession":"OP523982","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP523982/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI380"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}}},{"name":"OP605583","node_attrs":{"div":564,"accession":"OP605583","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.2"},"country":{"value":"Slovenia"},"strain_display":{"value":"Slovenia/OP605583/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Slovenia-MPXV-42-2022"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A161-","-607T","C17614A","C27187T","G111484A","G147305A","G150590-","G150593-","G150594-","G150599-","G150602-","C159401A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG030":["V74L"],"OPG043":["D257N"],"OPG130":["T140I"],"OPG185":["S162Y"]},"labels":{"aa":"OPG030: V74L; OPG043: D257N; OPG130: T140I; OPG185: S162Y"}}},{"name":"OP879766","node_attrs":{"div":559,"accession":"OP879766","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP879766/2022-07-25"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"NJ-MPXV-053"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-25"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ503817","node_attrs":{"div":570,"accession":"OQ503817","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ503817/2022-12-05"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00424/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-05"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C10929T","C25674T","C43493T","G51358A","C78473T","C90900T","G99544A","G102694A","G126646A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C168226T","C168586T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG023":["E658K"],"OPG063":["D66N"],"OPG070":["E257K"],"OPG118":["E367K"],"OPG148":["E221K"]},"labels":{"aa":"OPG023: E658K; OPG063: D66N; OPG070: E257K; OPG118: E367K; OPG148: E221K"}}},{"name":"OR086973","node_attrs":{"div":560,"accession":"OR086973","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.2"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR086973/2022-07-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_164/Belgium/2022"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-27"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G135633A","G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR759219","node_attrs":{"div":563,"accession":"OR759219","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.2"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OR759219/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/Canada/ON-PHOL131/2022"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C22034T","G108502A","C120425T","G120623A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"],"OPG037":["D134N"],"OPG137":["S275L"]},"labels":{"aa":"OPG037: D134N; OPG137: S275L"}}},{"name":"NODE_0000210","node_attrs":{"div":560,"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","T157527C"]}},"children":[{"name":"ON813262","node_attrs":{"div":560,"accession":"ON813262","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/ON813262/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI062"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OP555483","node_attrs":{"div":561,"accession":"OP555483","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.2"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555483/2022-07-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0387/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-12"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G154098A"]}}}]},{"name":"NODE_0000211","node_attrs":{"div":564,"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T26669C","G96073A","G115235A","C125294T","C135868T"],"OPG117":["D9N"]},"labels":{"aa":"OPG117: D9N"}},"children":[{"name":"OQ159027","node_attrs":{"div":565,"accession":"OQ159027","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ159027/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI632"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G77052A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}}},{"name":"OP959061","node_attrs":{"div":564,"accession":"OP959061","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.2"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP959061/2022-10-11"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"BOL-UNIMOL-MPX-293613-L"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-11"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000212","node_attrs":{"div":560,"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G45781A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG064":["H40Y"]},"labels":{"aa":"OPG064: H40Y"}},"children":[{"name":"OP539927","node_attrs":{"div":565,"accession":"OP539927","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP539927/2022-08-29"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00142/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-29"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C33082T","G40364A","C78447T","G148319A","C169975T"],"OPG049":["D24N"],"OPG058":["S24F"],"OPG100":["S147L"]},"labels":{"aa":"OPG049: D24N; OPG058: S24F; OPG100: S147L"}}},{"name":"OP555625","node_attrs":{"div":561,"accession":"OP555625","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.2"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555625/2022-08-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0554/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-30"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G29102A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"],"OPG045":["S54L"]},"labels":{"aa":"OPG045: S54L"}}},{"name":"OQ503811","node_attrs":{"div":563,"accession":"OQ503811","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ503811/2022-10-04"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00437/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-04"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C26253T","C103234T","C106176T"],"OPG042":["R282Q"],"OPG123":["D613N"]},"labels":{"aa":"OPG042: R282Q; OPG123: D613N"}}}]},{"name":"NODE_0000213","node_attrs":{"div":565,"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G8638A","C21548T","C47820T","C68218T","G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188236T","C188339T"],"OPG037":["D296N"],"OPG085":["R105Q"]},"labels":{"aa":"OPG037: D296N; OPG085: R105Q"}},"children":[{"name":"OQ979624","node_attrs":{"div":567,"accession":"OQ979624","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ979624/2023-02-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-028492/2023"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","G12239A","G12488A","-196615A"],"OPG023":["S138L","S221F"]},"labels":{"aa":"OPG023: S138L, S221F"}}},{"name":"OR427339","node_attrs":{"div":565,"accession":"OR427339","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR427339/2023-01-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-014981/2023"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","A196614-"]}}},{"name":"OR427343","node_attrs":{"div":566,"accession":"OR427343","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR427343/2023-03-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-038917/2023"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G100939A"]}}},{"name":"OR427335","node_attrs":{"div":566,"accession":"OR427335","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR427335/2023-04-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-043227/2023"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-04-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C102741T"],"OPG122":["S105L"]},"labels":{"aa":"OPG122: S105L"}}}]}]}]},{"name":"NODE_0000254","node_attrs":{"div":558,"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C25644T","-150590G","-150593G","-150594G","-150599G","-150602G"]},"labels":{"clade":"B.1.7"}},"children":[{"name":"ON843170","node_attrs":{"div":558,"accession":"ON843170","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.7"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/ON843170/2022-05-26"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0031/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-26"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}}},{"name":"OP539900","node_attrs":{"div":564,"accession":"OP539900","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.7"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP539900/2022-09-14"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00115/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-14"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C1735T","C52883T","C74175T","G86336A","C87677T","T149447C","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G195475A"],"OPG071":["R519K"],"OPG108":["R242C"],"OPG109":["D591N"]},"labels":{"aa":"OPG071: R519K; OPG108: R242C; OPG109: D591N"}}},{"name":"OP536774","node_attrs":{"div":560,"accession":"OP536774","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP536774/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"9000396"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","G50034A","G74200A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG069":["E17K"],"OPG094":["D141N"]},"labels":{"aa":"OPG069: E17K; OPG094: D141N"}}},{"name":"OP615340","node_attrs":{"div":562,"accession":"OP615340","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.7"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP615340/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI458"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G23359A","C40251T","C114955T","C116175T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG039":["L254F"],"OPG058":["D62N"],"OPG133":["D248N"]},"labels":{"aa":"OPG039: L254F; OPG058: D62N; OPG133: D248N"}}},{"name":"OQ547747","node_attrs":{"div":558,"accession":"OQ547747","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.7"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ547747/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI720"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G150551-","G150568-","A150569-","T150570-","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OP205081","node_attrs":{"div":558,"accession":"OP205081","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP205081/2022-06-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_UK_2022_9000078"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-14"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264370","node_attrs":{"div":560,"accession":"OR264370","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.7"},"country":{"value":"Australia"},"strain_display":{"value":"Australia/OR264370/2022-07-11"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"},"strain":{"value":"18_A"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-11"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G144556A","G150590-","G150593-","G150594-","G150599-","G150602-","C170573T","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","T179244-"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}}},{"name":"OR759218","node_attrs":{"div":560,"accession":"OR759218","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.7"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OR759218/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/Canada/ON-PHOL130/2022"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C81095T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C172410T"]}}},{"name":"NODE_0000169","node_attrs":{"div":559,"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G63147A","T179244-"]}},"children":[{"name":"ON927248","node_attrs":{"div":563,"accession":"ON927248","author":{"author":"Chan,W.Y.,Mtshali,P.S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J.","value":"Chan,W.Y.,Mtshali,P.S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J."},"lineage":{"value":"B.1.7"},"country":{"value":"South Africa"},"strain_display":{"value":"South Africa/ON927248/2022-06-24"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"},"strain":{"value":"NICD-SVPL232"},"institution":{"value":"National Institute for Communicable Disease, Sequencing core facility"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-24"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G10224A","G129761A","T143625A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C177847T","-179244T","A196601C","-196615A"],"OPG021":["R213Q"],"OPG151":["D280N"],"OPG165":["I37N"],"OPG205":["S731L"]},"labels":{"aa":"OPG021: R213Q; OPG151: D280N; OPG165: I37N; OPG205: S731L"}}},{"name":"OR264426","node_attrs":{"div":559,"accession":"OR264426","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.7"},"country":{"value":"Australia"},"strain_display":{"value":"Australia/OR264426/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"},"strain":{"value":"48_C"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T"]}}}]},{"name":"NODE_0000170","node_attrs":{"div":559,"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G120241A"],"OPG137":["D214N"]},"labels":{"aa":"OPG137: D214N"}},"children":[{"name":"ON911481","node_attrs":{"div":562,"accession":"ON911481","author":{"author":"Galan-Huerta,K.A.,Paz-Infanzon,M.,Ruiz-Higareda,A.F.,Nuzzolo-Shihadeh,L.,Camacho-Ortiz,A.,Bocanegra-Ibarias,P.,Rivas-Estilla,A.M.,Zacarias-Villarreal,D.,Yamallel-Ortega,L.A.,Guerrero-Putz,M.D.,Ocampo-Candiani,J.","value":"Galan-Huerta,K.A.,Paz-Infanzon,M.,Ruiz-Higareda,A.F.,Nuzzolo-Shihadeh,L.,Camacho-Ortiz,A.,Bocanegra-Ibarias,P.,Rivas-Estilla,A.M.,Zacarias-Villarreal,D.,Yamallel-Ortega,L.A.,Guerrero-Putz,M.D.,Ocampo-Candiani,J."},"lineage":{"value":"B.1.7"},"country":{"value":"Mexico"},"strain_display":{"value":"Mexico/ON911481/2022-06-28"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"Monkeypox/MX-UANL001/2022"},"institution":{"value":"Universidad Autonoma de Nuevo Leon - Facultad de Medicina, Centro de Investigacion e Innovacion en Virologia Medica"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-28"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","G57088A","C127530T","T133098-","T133099-","T133100-","T133101-","T133102-","G150590-","G150593-","G150594-","G150599-","G150602-","T168120C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG074":["S13L"],"OPG149":["S112L"],"OPG193":["F263L"]},"labels":{"aa":"OPG074: S13L; OPG149: S112L; OPG193: F263L"}}},{"name":"OP215210","node_attrs":{"div":559,"accession":"OP215210","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.7"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP215210/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI202"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}}}]},{"name":"NODE_0000171","node_attrs":{"div":560,"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G98456A","C103258T","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG118":["G4E"],"OPG123":["D605N"]},"labels":{"aa":"OPG118: G4E; OPG123: D605N"}},"children":[{"name":"OP225965","node_attrs":{"div":560,"accession":"OP225965","author":{"author":"Gigante,C.M.,Lee,P.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y."},"lineage":{"value":"B.1.7"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP225965/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_FL0012"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-"]}}},{"name":"OQ773497","node_attrs":{"div":561,"accession":"OQ773497","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.7"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ773497/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI878"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G9229A","G150551-","A150563-","T150564-","G150565-","A150566-","T150567-","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}}]},{"name":"NODE_0000172","node_attrs":{"div":559,"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C148771T"],"OPG174":["D209N"]},"labels":{"aa":"OPG174: D209N"}},"children":[{"name":"ON755249","node_attrs":{"div":559,"accession":"ON755249","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.7"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/ON755249/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI043"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}}},{"name":"NODE_0000173","node_attrs":{"div":561,"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G114316A","G152437A"],"OPG133":["H461Y"]},"labels":{"aa":"OPG133: H461Y"}},"children":[{"name":"OQ159026","node_attrs":{"div":562,"accession":"OQ159026","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.7"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ159026/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI631"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G150547A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G187677A"]}}},{"name":"OQ627928","node_attrs":{"div":561,"accession":"OQ627928","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"lineage":{"value":"B.1.7"},"country":{"value":"Italy"},"strain_display":{"value":"Italy/OQ627928/2022-09-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"INMI-19442022"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-14"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-608T","G610-","T611-","A612-","G150590-","G150593-","G150594-","G150599-","G150602-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","T179244-"]}}}]}]},{"name":"NODE_0000174","node_attrs":{"div":559,"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G42504A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}},"children":[{"name":"OP204840","node_attrs":{"div":560,"accession":"OP204840","author":{"author":"Seang,S.,Burrel,S.,Todesco,E.,Leducq,V.,Monsel,G.,Le Pluart,D.,Cordevant,C.,Pourcher,V.,Palich,R.,Charpentier,C.","value":"Seang,S.,Burrel,S.,Todesco,E.,Leducq,V.,Monsel,G.,Le Pluart,D.,Cordevant,C.,Pourcher,V.,Palich,R.,Charpentier,C."},"lineage":{"value":"B.1.7"},"country":{"value":"France"},"strain_display":{"value":"France/OP204840/2022-06-10"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"PatientMPXV"},"institution":{"value":"APHP Pitie Salpetriere SU, Virology"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-10"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G163250A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196612-","A196613-","A196614-"]}}},{"name":"OP414310","node_attrs":{"div":563,"accession":"OP414310","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.7"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP414310/2022-06-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0270/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-16"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C5292T","G74267A","C115870T","A161784T","G191918A"],"OPG015":["D289N"],"OPG015_dup":["D289N"],"OPG094":["R163Q"]},"labels":{"aa":"OPG015: D289N; OPG015_dup: D289N; OPG094: R163Q"}}},{"name":"OP555475","node_attrs":{"div":559,"accession":"OP555475","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.7"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555475/2022-07-06"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0379/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-06"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OP555558","node_attrs":{"div":561,"accession":"OP555558","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.7"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555558/2022-08-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0479/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-09"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","C134850T","C159741T","A196614-"]}}}]},{"name":"NODE_0000176","node_attrs":{"div":559,"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C14077T","G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP205084","node_attrs":{"div":561,"accession":"OP205084","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP205084/2022-05-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_UK_2022_9000093"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-30"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C4529T","G155585A","G192681A"],"OPG003":["D27N"],"OPG003_dup":["D27N"]},"labels":{"aa":"OPG003: D27N; OPG003_dup: D27N"}}},{"name":"OP415222","node_attrs":{"div":562,"accession":"OP415222","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP415222/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX_12DvO8_9000251"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G27260A","G46325A","G147799A"],"OPG172":["A125T"]},"labels":{"aa":"OPG172: A125T"}}},{"name":"OP415186","node_attrs":{"div":559,"accession":"OP415186","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP415186/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX_cmjxZM_9000205"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000177","node_attrs":{"div":560,"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G105860A"]}},"children":[{"name":"OP415198","node_attrs":{"div":562,"accession":"OP415198","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP415198/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX_2v76E1_9000222"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G41557A","G91376A"],"OPG061":["P110S"],"OPG112":["D44N"]},"labels":{"aa":"OPG061: P110S; OPG112: D44N"}}},{"name":"OR095063","node_attrs":{"div":560,"accession":"OR095063","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.7"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR095063/2022-08-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_245/Belgium/2022"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-16"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}}]}]},{"name":"NODE_0000178","node_attrs":{"div":559,"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C57173T","G150590-","G150593-","G150594-","G150599-","G150602-"]}},"children":[{"name":"OP727822","node_attrs":{"div":566,"accession":"OP727822","author":{"author":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K.","value":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K."},"lineage":{"value":"B.1.7"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OP727822/2022-10-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"PrEV_case_2"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-02"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T604-","T605-","T606-","C11401T","C33964T","C36267T","G110285A","T133099-","C144366T","A174924T","G180608A","A188351-","G195316A"],"OPG052":["R11Q"],"OPG055":["D273N"],"OPG209":["E31K"]},"labels":{"aa":"OPG052: R11Q; OPG055: D273N; OPG209: E31K"}}},{"name":"NODE_0000179","node_attrs":{"div":560,"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C142797T"],"OPG164":["S7L"]},"labels":{"aa":"OPG164: S7L"}},"children":[{"name":"OP279036","node_attrs":{"div":560,"accession":"OP279036","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.7"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OP279036/2022-06-30"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/CAN/UN-NML-4112/2022"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-30"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP597782","node_attrs":{"div":563,"accession":"OP597782","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"lineage":{"value":"B.1.7"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP597782/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MN-MDH-MPXV_0008"},"institution":{"value":"Minnesota Department of Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G74619A","G83118A","T87356C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG105":["A665T"],"OPG109":["K698E"]},"labels":{"aa":"OPG105: A665T; OPG109: K698E"}}},{"name":"OR264396","node_attrs":{"div":565,"accession":"OR264396","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.7"},"country":{"value":"Australia"},"strain_display":{"value":"Australia/OR264396/2022-09-07"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"},"strain":{"value":"33_A"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-07"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G14622A","A28531-","A28532-","T76084-","T76085-","G101241A","T133099-","C136244T","C156446T","G174708A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","T179244-"],"OPG025":["R216C"],"OPG044":["M148-"],"OPG153":["R475K"],"OPG204":["M59I"]},"labels":{"aa":"OPG025: R216C; OPG044: M148-; OPG153: R475K; OPG204: M59I"}}},{"name":"OR209323","node_attrs":{"div":561,"accession":"OR209323","author":{"author":"Li,C.M.","value":"Li,C.M."},"lineage":{"value":"B.1.7"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR209323/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_NC0003"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","G62268A","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","A196614-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OR759178","node_attrs":{"div":564,"accession":"OR759178","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.7"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OR759178/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/Canada/ON-PHOL090/2022"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","G26352A","C30137T","C55072T","G130068A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"],"OPG042":["A249V"],"OPG047":["R353K"],"OPG073":["D24N"],"OPG151":["R382Q"]},"labels":{"aa":"OPG042: A249V; OPG047: R353K; OPG073: D24N; OPG151: R382Q"}}},{"name":"NODE_0000180","node_attrs":{"div":561,"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C108658T"]}},"children":[{"name":"OP743961","node_attrs":{"div":563,"accession":"OP743961","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.7"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP743961/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-086295/2022"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C32211T","G119968A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG049":["R314H"],"OPG137":["E123K"]},"labels":{"aa":"OPG049: R314H; OPG137: E123K"}}},{"name":"OP920699","node_attrs":{"div":566,"accession":"OP920699","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"lineage":{"value":"B.1.7"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP920699/2022-10-31"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00361/2022"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-31"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G105325A","G111379A","C149889T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G165395A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G184244A"],"OPG124":["S215F"],"OPG130":["S175L"],"OPG190":["E92K"]},"labels":{"aa":"OPG124: S215F; OPG130: S175L; OPG190: E92K"}}}]},{"name":"NODE_0000181","node_attrs":{"div":564,"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C55036T","C96914T","G158254A","C170381T","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179176A","-179177T","-179178A","-179179T","-179180A"],"OPG073":["E36K"],"OPG117":["S289L"],"OPG198":["S115L"]},"labels":{"aa":"OPG073: E36K; OPG117: S289L; OPG198: S115L"}},"children":[{"name":"OQ918697","node_attrs":{"div":568,"accession":"OQ918697","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.7"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ918697/2023-02-18"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00486/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-18"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G73789A","C136435T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C166803T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","G178559A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG094":["G4R"],"OPG192":["P25S"]},"labels":{"aa":"OPG094: G4R; OPG192: P25S"}}},{"name":"OR464216","node_attrs":{"div":564,"accession":"OR464216","author":{"author":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y.","value":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y."},"lineage":{"value":"B.1.7"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR464216/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_KS0007"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T"]}}}]}]}]}]},{"name":"NODE_0000214","node_attrs":{"div":558,"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G74360A","-179181C","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG094":["R194H"]},"labels":{"aa":"OPG094: R194H","clade":"B.1.1"}},"children":[{"name":"OP184763","node_attrs":{"div":558,"accession":"OP184763","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP184763/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-076773/2022"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"]}}},{"name":"ON792321","node_attrs":{"div":558,"accession":"ON792321","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"lineage":{"value":"B.1.1"},"country":{"value":"Switzerland"},"strain_display":{"value":"Switzerland/ON792321/2022-06-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba6450e/2022"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-02"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","A19360-","T19361-","C19362-","A19363-","T19364-","T19365-","A43653-","T43654-","T43655-","A49176-","A49177-","T49178-","T49179-","T49180-","T49181-","A49182-","T49183-","T49184-","A49185-","A49186-","C49187-","G49188-","G49189-","T49190-","A49191-","A49192-","T49193-","A79063-","A79064-","T79065-","T79066-","T79067-","T79068-","A79069-","A79070-","T79071-","A79072-","T79073-","A79074-","A79075-","T79076-","A79077-","C79078-","T79079-","T79080-","A79081-","A79082-","A79083-","A79084-","A79085-","T79086-","G79087-","G79088-","A79089-","T79090-","G79091-","T79092-","T79093-","G79094-","T79095-","G79096-","T79097-","C79098-","G79099-","T79100-","T79101-","A79102-","A152691-","A152692-","T152693-","G152694-","A152695-","C152696-","G152697-","T152698-","A175944-","T175945-","A175946-","T175947-","C175948-","A175949-","A175950-","C179127A","C179136T","T179138A","T179148-","T179157-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179181-","-179190T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T180493-","A180494-","T180495-","C180496-","A180497-","T180498-","T180499-"],"OPG063":["D50-"],"OPG068":["N329-","G330-","N331-","T332-","F333-","I334-"],"OPG205":["I97-","S98-","I99-"]},"labels":{"aa":"OPG063: D50-; OPG068: N329-, G330-, N331-, T332-, F333-, I334-; OPG205: I97-, S98-, I99-"}}},{"name":"OP303785","node_attrs":{"div":558,"accession":"OP303785","author":{"author":"Gigante,C.M.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.M.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"lineage":{"value":"B.1.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP303785/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_IL0042"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179181-","A179185-","T179186-","A179187-","T179188-","A179189-"]}}},{"name":"OP257257","node_attrs":{"div":559,"accession":"OP257257","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP257257/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-080706/2022"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","C68675T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"]}}},{"name":"OP204857","node_attrs":{"div":560,"accession":"OP204857","author":{"author":"Rhie,G.-E.","value":"Rhie,G.-E."},"lineage":{"value":"B.1.1"},"country":{"value":"South Korea"},"strain_display":{"value":"South Korea/OP204857/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MPXV-ROK-P1-2022"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C786T","C71728T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G173429A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG091":["A120V"]},"labels":{"aa":"OPG091: A120V"}}},{"name":"OP382488","node_attrs":{"div":559,"accession":"OP382488","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1.1"},"country":{"value":"France"},"strain_display":{"value":"France/OP382488/2022-07-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMPXV-IHU00011"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-19"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C153387T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP837475","node_attrs":{"div":560,"accession":"OP837475","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.1"},"country":{"value":"Colombia"},"strain_display":{"value":"Colombia/OP837475/2022-09-19"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"strain":{"value":"DC_INS_MPX_1009_L"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-19"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C17764T","G54336A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG030":["D24N"],"OPG071":["P35S"]},"labels":{"aa":"OPG030: D24N; OPG071: P35S"}}},{"name":"OP837335","node_attrs":{"div":558,"accession":"OP837335","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP837335/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI573"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179181-","A179185-","T179186-","A179187-","T179188-","A179189-"]}}},{"name":"OQ547751","node_attrs":{"div":558,"accession":"OQ547751","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ547751/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI724"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OR427334","node_attrs":{"div":566,"accession":"OR427334","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR427334/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-121247/2022"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","C11810T","G52232A","G59218A","C63120T","G75522A","C119838T","C159899T","G160110A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG023":["R364K"],"OPG071":["S736L"],"OPG079":["S135L"]},"labels":{"aa":"OPG023: R364K; OPG071: S736L; OPG079: S135L"}}},{"name":"OR264399","node_attrs":{"div":560,"accession":"OR264399","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"country":{"value":"Australia"},"strain_display":{"value":"Australia/OR264399/2022-06-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"},"strain":{"value":"36_A"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-30"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A28531-","A28532-","A43500-","T76084-","T76085-","T80846-","T80847-","A89106-","G118500A","T121121-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","G160406A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","T179244-","C196772-","A196773-","T196774-"],"OPG044":["M148-"],"OPG136":["T363M"]},"labels":{"aa":"OPG044: M148-; OPG136: T363M"}}},{"name":"OR095036","node_attrs":{"div":561,"accession":"OR095036","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.1"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR095036/2022-08-08"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_218/Belgium/2022"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-08"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C25828T","G107496A","G109463A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG042":["E424K"]},"labels":{"aa":"OPG042: E424K"}}},{"name":"OR500080","node_attrs":{"div":567,"accession":"OR500080","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"country":{"value":"Romania"},"strain_display":{"value":"Romania/OR500080/2022-08-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMpxV/Romania/B-18/2022"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-16"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G17189T","A55140C","T55141A","T75369C","T91506G","G121663A","T169776C","A173282G","A173284G","T174471A","G179029T","A179046T","A179081T","A179110T","T179121A","C179127T","T179129-","T179130-","T179139A","-179172A","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179190T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C179672A","C181209T"],"OPG073":["M1W"],"OPG074":["N662M"],"OPG208":["S136Y"]},"labels":{"aa":"OPG073: M1W; OPG074: N662M; OPG208: S136Y"}}},{"name":"OR500078","node_attrs":{"div":558,"accession":"OR500078","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"country":{"value":"Romania"},"strain_display":{"value":"Romania/OR500078/2022-06-29"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMpxV/Romania/B-8/2022"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-29"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T92388-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["F220-"]},"labels":{"aa":"OPG113: F220-"}}},{"name":"ON694329","node_attrs":{"div":558,"accession":"ON694329","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/ON694329/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI025"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179181-","A179185-","T179186-","A179187-","T179188-","A179189-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-","A192490-","A192491-","G192492-","T192493-","T192494-","A192495-","G192496-","T192497-","T192498-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP484663","node_attrs":{"div":558,"accession":"OP484663","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP484663/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI340"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179181-","A179185-","T179186-","A179187-","T179188-","A179189-"]}}},{"name":"NODE_0000216","node_attrs":{"div":561,"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C17048T","G93828A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177009A","C179181-","A179185-","T179186-","A179187-","T179188-","A179189-"],"OPG029":["D8N"],"OPG113":["E700K"],"OPG205":["E452K"]},"labels":{"aa":"OPG029: D8N; OPG113: E700K; OPG205: E452K"}},"children":[{"name":"OQ159028","node_attrs":{"div":562,"accession":"OQ159028","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ159028/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI633"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C41131T"],"OPG060":["E18K"]},"labels":{"aa":"OPG060: E18K"}}},{"name":"OQ735077","node_attrs":{"div":568,"accession":"OQ735077","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.1"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OQ735077/2023-03-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/PT0626/2023"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-21"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-609T","A615-","C616-","C10929T","C22179T","G39515A","G77076A","G129659A","C129949T","G139167A","C196638-","T196639-"],"OPG023":["E658K"],"OPG151":["E246K"]},"labels":{"aa":"OPG023: E658K; OPG151: E246K"}}}]},{"name":"NODE_0000217","node_attrs":{"div":559,"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C11401T","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}},"children":[{"name":"OQ427112","node_attrs":{"div":561,"accession":"OQ427112","author":{"author":"Gigante,C.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y.","value":"Gigante,C.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y."},"lineage":{"value":"B.1.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ427112/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_NV0005"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C72269T","T133099-","G140194A","G158318A"],"OPG092":["D227N"],"OPG159":["D143N"],"OPG160":["S294L"]},"labels":{"aa":"OPG092: D227N; OPG159: D143N; OPG160: S294L"}}},{"name":"OQ721942","node_attrs":{"div":561,"accession":"OQ721942","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"lineage":{"value":"B.1.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ721942/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_TX0051"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G23673A","G50121A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"],"OPG039":["S149L"],"OPG069":["E46K"]},"labels":{"aa":"OPG039: S149L; OPG069: E46K"}}}]},{"name":"NODE_0000218","node_attrs":{"div":563,"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C46672T","C56805T","C72314T","C103216T","T152686-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C180857T"],"OPG066":["E253K"],"OPG074":["M107I"],"OPG092":["D212N"],"OPG123":["V619I"]},"labels":{"aa":"OPG066: E253K; OPG074: M107I; OPG092: D212N; OPG123: V619I"}},"children":[{"name":"OR500083","node_attrs":{"div":565,"accession":"OR500083","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"country":{"value":"Romania"},"strain_display":{"value":"Romania/OR500083/2023-02-15"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMpxV/Romania/B-35_L3/2023"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-15"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C9781T","G127563A"],"OPG149":["R123Q"]},"labels":{"aa":"OPG149: R123Q"}}},{"name":"OR500081","node_attrs":{"div":565,"accession":"OR500081","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"country":{"value":"Romania"},"strain_display":{"value":"Romania/OR500081/2023-01-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMpxV/Romania/B-35_L1/2023"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-05"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C16327T","C127628T"],"OPG149":["P145S"]},"labels":{"aa":"OPG149: P145S"}}}]},{"name":"NODE_0000219","node_attrs":{"div":559,"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C29887T","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","T179244-"]}},"children":[{"name":"OP215247","node_attrs":{"div":559,"accession":"OP215247","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP215247/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI211"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179181-","A179185-","T179186-","A179187-","T179188-","A179189-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","T179226-","-179244T"]}}},{"name":"OR264438","node_attrs":{"div":560,"accession":"OR264438","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"country":{"value":"Australia"},"strain_display":{"value":"Australia/OR264438/2022-09-06"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"},"strain":{"value":"56_D"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-06"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A28531-","A28532-","T76084-","T76085-","C89382T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"],"OPG044":["M148-"]},"labels":{"aa":"OPG044: M148-"}}},{"name":"OR264410","node_attrs":{"div":559,"accession":"OR264410","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"country":{"value":"Australia"},"strain_display":{"value":"Australia/OR264410/2022-07-29"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"},"strain":{"value":"3_A"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-29"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-196615A"]}}},{"name":"OR264371","node_attrs":{"div":559,"accession":"OR264371","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"country":{"value":"Australia"},"strain_display":{"value":"Australia/OR264371/2022-08-24"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"},"strain":{"value":"19_A"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-24"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T76084-","T76085-","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"]}}}]},{"name":"NODE_0000220","node_attrs":{"div":559,"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155698A","C179181-","A179185-","T179186-","A179187-","T179188-","A179189-"]}},"children":[{"name":"OP555659","node_attrs":{"div":564,"accession":"OP555659","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.1"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555659/2022-09-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0592/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-14"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G685-","T686-","C21910T","C67207T","G81244A","G109451A","G138237A","-196615A"],"OPG037":["R175K"],"OPG085":["R442K"],"OPG105":["R40K"]},"labels":{"aa":"OPG037: R175K; OPG085: R442K; OPG105: R40K"}}},{"name":"OR759194","node_attrs":{"div":568,"accession":"OR759194","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.1"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OR759194/2022-07-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/Canada/ON-PHOL106/2022"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C7235T","C32798T","C55589T","C61706T","G115768A","T120124-","T120125-","A120126-","G120127-","A120128-","T120129-","A120130-","A120131-","T120132-","G127806A","G159118A","G162726A","C177833T"],"OPG074":["E513K"],"OPG080":["V105I"],"OPG134":["D7N"],"OPG137":["L175-","D176-","N177-"],"OPG150":["E10K"],"OPG185":["D68N"]},"labels":{"aa":"OPG074: E513K; OPG080: V105I; OPG134: D7N; OPG137: L175-, D176-, N177-; OPG150: E10K; OPG185: D68N"}}},{"name":"NODE_0000221","node_attrs":{"div":560,"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G161575A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OR459775","node_attrs":{"div":562,"accession":"OR459775","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"B.1.1"},"country":{"value":"South Korea"},"strain_display":{"value":"South Korea/OR459775/2022-09-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MPXV-ROK-P002-2022"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-02"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G14640A","C108843T","G136558C"],"OPG025":["H210Y"],"OPG153":["I370M"]},"labels":{"aa":"OPG025: H210Y; OPG153: I370M"}}},{"name":"OR086942","node_attrs":{"div":560,"accession":"OR086942","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.1"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR086942/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_133/Belgium/2022"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T133099-","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","A196748-","T196749-","C196750-"]}}}]}]},{"name":"NODE_0000222","node_attrs":{"div":559,"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C22739T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T"],"OPG038":["E141K"]},"labels":{"aa":"OPG038: E141K"}},"children":[{"name":"OP019276","node_attrs":{"div":559,"accession":"OP019276","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1.1"},"country":{"value":"Austria"},"strain_display":{"value":"Austria/OP019276/2022-06-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMPXV/Austria/MUW1527495/2022"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-21"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP018606","node_attrs":{"div":561,"accession":"OP018606","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP018606/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI184"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G21655A","G135221A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-"],"OPG037":["S260L"]},"labels":{"aa":"OPG037: S260L"}}},{"name":"ON808413","node_attrs":{"div":559,"accession":"ON808413","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"lineage":{"value":"B.1.1"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/ON808413/2022-05-15"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"CVR_MPXV1a"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-15"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP205128","node_attrs":{"div":559,"accession":"OP205128","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.1"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP205128/2022-06-26"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_UK_2022_9000179"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-26"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000223","node_attrs":{"div":561,"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C22740T","C38937T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-"],"OPG056":["R33Q"]},"labels":{"aa":"OPG056: R33Q"}},"children":[{"name":"OP415276","node_attrs":{"div":562,"accession":"OP415276","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.1"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP415276/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX_KV9qz9_9000349"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C67659T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG085":["M291I"]},"labels":{"aa":"OPG085: M291I"}}},{"name":"OP555496","node_attrs":{"div":562,"accession":"OP555496","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.1"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555496/2022-07-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0400/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-19"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G174240A"]}}},{"name":"OP555627","node_attrs":{"div":564,"accession":"OP555627","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.1"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555627/2022-08-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0556/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-30"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","G74362A","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","T136555-","A136556-","T136557-","G136558-","A136559-","T136560-","A136561-","T136562-","C136563-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G157775A","C177240T","-196615A"],"OPG094":["A195T"],"OPG153":["I370-","I371-","D372-","D373-","D374-","D375-","D376-","D377-"],"OPG205":["Q529*"]},"labels":{"aa":"OPG094: A195T; OPG153: I370-, I371-, D372-, D373-, D374-, D375-, D376-, D377-; OPG205: Q529*"}}}]}]}]},{"name":"NODE_0000224","node_attrs":{"div":558,"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G190660A"],"OPG016":["R84K"]},"labels":{"aa":"OPG016: R84K","clade":"B.1.3"}},"children":[{"name":"OP150924","node_attrs":{"div":559,"accession":"OP150924","author":{"author":"Gigante,C.,Ventura,J.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Sheth,M.,Li,Y.","value":"Gigante,C.,Ventura,J.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Sheth,M.,Li,Y."},"lineage":{"value":"B.1.3"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP150924/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_CA006"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C17752T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG030":["E28K"]},"labels":{"aa":"OPG030: E28K"}}},{"name":"ON983168","node_attrs":{"div":558,"accession":"ON983168","author":{"author":"Chmel,M.,Pajer,P.,Nagy,A.,Zlamal,M.,Jirincova,H.,Dresler,J.,Bartos,O.","value":"Chmel,M.,Pajer,P.,Nagy,A.,Zlamal,M.,Jirincova,H.,Dresler,J.,Bartos,O."},"lineage":{"value":"B.1.3"},"country":{"value":"Czech Republic"},"strain_display":{"value":"Czech Republic/ON983168/2022-04-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPxV/Prague_001/2022/flye_medaka"},"institution":{"value":"Military Heatlh Institute, Military Heatlh Institute in Prague"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-04-28"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T80849-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OP536795","node_attrs":{"div":558,"accession":"OP536795","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.3"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP536795/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"9000421"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OP727821","node_attrs":{"div":558,"accession":"OP727821","author":{"author":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K.","value":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K."},"lineage":{"value":"B.1.3"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OP727821/2022-08-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"PrEV_case_1"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-27"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A173314-","T173315-","A173316-","T173317-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-"]}}},{"name":"NODE_0000225","node_attrs":{"div":562,"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C39898T","C148933T","G171318A","C175241T"],"OPG057":["D100N"],"OPG174":["E155K"],"OPG199":["E111K"],"OPG204":["S237L"]},"labels":{"aa":"OPG057: D100N; OPG174: E155K; OPG199: E111K; OPG204: S237L"}},"children":[{"name":"OP205121","node_attrs":{"div":562,"accession":"OP205121","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.3"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP205121/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_UK_2022_9000164"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OP536779","node_attrs":{"div":563,"accession":"OP536779","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.3"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP536779/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"9000403"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","C17196T","A62041-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"]}}}]},{"name":"NODE_0000226","node_attrs":{"div":559,"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C64426T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}},"children":[{"name":"OQ721953","node_attrs":{"div":566,"accession":"OQ721953","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"B.1.3"},"country":{"value":"Taiwan"},"strain_display":{"value":"Taiwan/OQ721953/2023-03-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MPXV/human/Taiwan/110-525030/2023"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C166940T","T177665A","A177666T","A177667T","G178104T","G178290T","T178629A","G196412A"],"OPG205":["N670K","N671F"]},"labels":{"aa":"OPG205: N670K, N671F"}}},{"name":"NODE_0000227","node_attrs":{"div":560,"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G55133A"],"OPG074":["R665C"]},"labels":{"aa":"OPG074: R665C"}},"children":[{"name":"ON853669","node_attrs":{"div":561,"accession":"ON853669","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.3"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/ON853669/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI089"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A36620C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG055":["V155G"]},"labels":{"aa":"OPG055: V155G"}}},{"name":"ON782055","node_attrs":{"div":562,"accession":"ON782055","author":{"author":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"lineage":{"value":"B.1.3"},"country":{"value":"Spain"},"strain_display":{"value":"Spain/ON782055/2022-05-31"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0001b/2022"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-31"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A48265T","C48296G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG068":["D22V"]},"labels":{"aa":"OPG068: D22V"}}},{"name":"ON792320","node_attrs":{"div":561,"accession":"ON792320","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"lineage":{"value":"B.1.3"},"country":{"value":"Switzerland"},"strain_display":{"value":"Switzerland/ON792320/2022-06-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba6449f/2022"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G159376A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG185":["D154N"]},"labels":{"aa":"OPG185: D154N"}}},{"name":"ON754985","node_attrs":{"div":560,"accession":"ON754985","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"country":{"value":"Slovenia"},"strain_display":{"value":"Slovenia/ON754985/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_SI2022_S4"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A33-","T157-","-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON754987","node_attrs":{"div":561,"accession":"ON754987","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"country":{"value":"Slovenia"},"strain_display":{"value":"Slovenia/ON754987/2022-05-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_SI2022_S1_VEROE6"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-23"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A33-","T157-","-607T","G167517A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG193":["E62K"]},"labels":{"aa":"OPG193: E62K"}}},{"name":"ON622722","node_attrs":{"div":561,"accession":"ON622722","lineage":{"value":"B.1.3"},"country":{"value":"France"},"strain_display":{"value":"France/ON622722/2022-05-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_FR_HCL0001_2022"},"institution":{"value":"Virology, GENomique EPIdemiologique das maladies Infectieuses, France"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-22"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C109627A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG129":["A460S"]},"labels":{"aa":"OPG129: A460S"}}},{"name":"OP215273","node_attrs":{"div":562,"accession":"OP215273","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.3"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP215273/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI251"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G5515A","T54004C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179259T","C191695T"]}}},{"name":"OP205133","node_attrs":{"div":561,"accession":"OP205133","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.3"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP205133/2022-06-29"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_UK_2022_9000188"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-29"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","C142545T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG163":["S115F"]},"labels":{"aa":"OPG163: S115F"}}},{"name":"OP205067","node_attrs":{"div":560,"accession":"OP205067","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.3"},"country":{"value":"United Kingdom"},"strain_display":{"value":"United Kingdom/OP205067/2022-05-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV_UK_2022_9000061"},"institution":{"value":"UKHSA, Research and Evaluation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-27"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OP484692","node_attrs":{"div":564,"accession":"OP484692","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.3"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OP484692/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/RKI371"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G101152A","G124855T","G141131A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C180490G"],"OPG145":["E303D"]},"labels":{"aa":"OPG145: E303D"}}},{"name":"OP555633","node_attrs":{"div":561,"accession":"OP555633","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.3"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555633/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0562/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168066T"],"OPG153":["D385-"],"OPG193":["Q245*"]},"labels":{"aa":"OPG153: D385-; OPG193: Q245*"}}},{"name":"OP555585","node_attrs":{"div":560,"accession":"OP555585","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.3"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555585/2022-08-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0514/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-16"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OQ274888","node_attrs":{"div":560,"accession":"OQ274888","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.3"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ274888/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI669"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OR035732","node_attrs":{"div":561,"accession":"OR035732","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.3"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR035732/2022-10-03"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_126"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-03"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G92135A","T133099-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264391","node_attrs":{"div":560,"accession":"OR264391","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.3"},"country":{"value":"Australia"},"strain_display":{"value":"Australia/OR264391/2022-08-10"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"},"strain":{"value":"2_A"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-10"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T80846-","T80847-","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","T179244-"]}}},{"name":"OR134560","node_attrs":{"div":571,"accession":"OR134560","author":{"author":"Miller,H.,Bajwa,M.","value":"Miller,H.,Bajwa,M."},"lineage":{"value":"B.1.3"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR134560/2023-03-13"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"B1221136"},"institution":{"value":"Delaware Public Health Lab, Sequencing/Bioinformatics"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-13"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C19558T","G32277A","C35688T","G39140A","G55059A","G75512A","C110402T","C121161T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C170673T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179542T","C189174T"],"OPG034":["E150K"],"OPG049":["S292L"],"OPG073":["S28L"],"OPG095":["R237K"],"OPG139":["A70T"]},"labels":{"aa":"OPG034: E150K; OPG049: S292L; OPG073: S28L; OPG095: R237K; OPG139: A70T"}}},{"name":"OX248696","node_attrs":{"div":562,"accession":"OX248696","lineage":{"value":"B.1.3"},"country":{"value":"Slovakia"},"strain_display":{"value":"Slovakia/OX248696/2022-07-04"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"RNA"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-04"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","G37250A","C138080T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG155":["E138K"]},"labels":{"aa":"OPG155: E138K"}}},{"name":"OR759179","node_attrs":{"div":562,"accession":"OR759179","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.3"},"country":{"value":"Canada"},"strain_display":{"value":"Canada/OR759179/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"hMpxV/Canada/ON-PHOL091/2022"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-01"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G85581A","C122502T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG107":["V24I"],"OPG143":["D272N"]},"labels":{"aa":"OPG107: V24I; OPG143: D272N"}}},{"name":"OR463762","node_attrs":{"div":561,"accession":"OR463762","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.3"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OR463762/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2022/ON/RKI769"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C3047T","G150551-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","A181253-"],"OPG003":["D521N"]},"labels":{"aa":"OPG003: D521N"}}},{"name":"OP604565","node_attrs":{"div":560,"accession":"OP604565","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"lineage":{"value":"B.1.3"},"country":{"value":"USA"},"strain_display":{"value":"USA/OP604565/2022-08-24"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV22/human/USA-NE-211"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-24"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"OQ557947","node_attrs":{"div":560,"accession":"OQ557947","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"lineage":{"value":"B.1.3"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ557947/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_NY0008"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A"]}}},{"name":"ON782021","node_attrs":{"div":560,"accession":"ON782021","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O."},"lineage":{"value":"B.1.3"},"country":{"value":"Finland"},"strain_display":{"value":"Finland/ON782021/2022-05-24"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPX-37/Finland/2022"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-24"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ054221","node_attrs":{"div":560,"accession":"OQ054221","author":{"author":"Gigante,C.,Hottel,W.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nelson,M.,Li,Y.","value":"Gigante,C.,Hottel,W.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nelson,M.,Li,Y."},"lineage":{"value":"B.1.3"},"country":{"value":"USA"},"strain_display":{"value":"USA/OQ054221/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV_USA_2022_IA0002"},"institution":{"value":"CDC, DHCPP-PRB"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","A196614-"]}}},{"name":"NODE_0000228","node_attrs":{"div":561,"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A140126-","C140127-","T168120C","-179234A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-"],"OPG159":["N120-"],"OPG193":["F263L"]},"labels":{"aa":"OPG159: N120-; OPG193: F263L"}},"children":[{"name":"OP144214","node_attrs":{"div":562,"accession":"OP144214","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P."},"lineage":{"value":"B.1.3"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OP144214/2022-06-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/ITM_pt_25/Belgium/16-Jun-2022"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-16"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C133161T","C157632T"]}}},{"name":"ON950045","node_attrs":{"div":561,"accession":"ON950045","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,Van den Bossche,D.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Van Esbroeck,M.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,Van den Bossche,D.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Van Esbroeck,M."},"lineage":{"value":"B.1.3"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/ON950045/2022-05-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/ITM_pt_31/Belgium/27-May-2022"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-27"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T133099-","A140104-","A140105-","T140106-","A140107-","A140108-","C140109-","A140110-","A140111-","T140112-","T140113-","A140114-","T140115-","A140116-","A140117-","C140118-","A140119-","A140120-","T140121-","T140122-","A140123-","T140124-","A140125-","A140128-","A140129-","T140130-","T140131-","A140132-","T140133-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","A140143-","A140144-","T140145-","T140146-","G140147-","T140148-","T140149-","A140150-","T140151-","A140152-","A140153-","T140154-","A140155-","A140156-","T140157-","T140158-","A140159-","T140160-","A140161-","A140162-","T140163-","T140164-","G140165-","T140166-","T140167-","T179267-","-196615A"],"OPG159":["N113-","N114-","N115-","Y116-","N117-","N118-","Y119-","N121-","Y122-","N123-","N124-","Y125-","N126-","C127-","Y128-","N129-","N130-","Y131-","N132-","C133-","Y134-"]},"labels":{"aa":"OPG159: N113-, N114-, N115-, Y116-, N117-, N118-, Y119-, N121-, Y122-, N123-, N124-, Y125-, N126-, C127-, Y128-, N129-, N130-, Y131-, N132-, C133-, Y134-"}}}]},{"name":"NODE_0000229","node_attrs":{"div":561,"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C133161T","C157632T"]}},"children":[{"name":"OP555472","node_attrs":{"div":562,"accession":"OP555472","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.3"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OP555472/2022-07-07"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0376/2022"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-07"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159243A"]}}},{"name":"OR086974","node_attrs":{"div":562,"accession":"OR086974","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.3"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR086974/2022-07-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_165/Belgium/2022"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-27"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G41336A","T133099-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000230","node_attrs":{"div":563,"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["A204-","-607T","C8612T","C56018T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G187156A"],"OPG074":["E370K"]},"labels":{"aa":"OPG074: E370K"}},"children":[{"name":"OP605581","node_attrs":{"div":564,"accession":"OP605581","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"country":{"value":"Slovenia"},"strain_display":{"value":"Slovenia/OP605581/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Slovenia-MPXV-40-2022"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G52232A"],"OPG071":["S736L"]},"labels":{"aa":"OPG071: S736L"}}},{"name":"OP605570","node_attrs":{"div":563,"accession":"OP605570","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"country":{"value":"Slovenia"},"strain_display":{"value":"Slovenia/OP605570/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Slovenia-MPXV-28-2022"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000231","node_attrs":{"div":561,"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G152776A"],"OPG180":["D29N"]},"labels":{"aa":"OPG180: D29N"}},"children":[{"name":"OQ451904","node_attrs":{"div":572,"accession":"OQ451904","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.3"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OQ451904/2023-01-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2023/RKI719"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","C15969T","C17998T","G40610A","C43803T","C63879T","G70190A","G118289A","C147011T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C159532T","G161629A","C189427T"],"OPG005":["P77S"],"OPG027":["E137K"],"OPG031":["M277I"],"OPG064":["G699E"],"OPG083":["D280N"],"OPG089":["E109K"],"OPG185":["P206S"],"OPG188":["E12K"]},"labels":{"aa":"OPG005: P77S; OPG027: E137K; OPG031: M277I; OPG064: G699E; OPG083: D280N; OPG089: E109K; OPG185: P206S; OPG188: E12K"}}},{"name":"OQ581854","node_attrs":{"div":563,"accession":"OQ581854","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"B.1.3"},"country":{"value":"Taiwan"},"strain_display":{"value":"Taiwan/OQ581854/2023-02-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MPXV/human/Taiwan/109-005210/2023"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T64426C","G158406A","A192404-","G192405-","T192406-","A192411-"]}}}]},{"name":"NODE_0000235","node_attrs":{"div":561,"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G105923A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG124":["L16F"]},"labels":{"aa":"OPG124: L16F","clade":"C.1"}},"children":[{"name":"LC753970","node_attrs":{"div":561,"accession":"LC753970","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"C.1"},"country":{"value":"Japan"},"strain_display":{"value":"Japan/LC753970/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220187"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"LC753968","node_attrs":{"div":561,"accession":"LC753968","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"C.1"},"country":{"value":"Japan"},"strain_display":{"value":"Japan/LC753968/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220165"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}},{"name":"OR035728","node_attrs":{"div":562,"accession":"OR035728","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"C.1"},"country":{"value":"Belgium"},"strain_display":{"value":"Belgium/OR035728/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/UZ_REGA_122"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T133099-","G149818A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG176":["D4N"]},"labels":{"aa":"OPG176: D4N"}}},{"name":"OQ581853","node_attrs":{"div":563,"accession":"OQ581853","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"C.1"},"country":{"value":"Taiwan"},"strain_display":{"value":"Taiwan/OQ581853/2023-02-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MPXV/human/Taiwan/110-093831/2023"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T132513C","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C185069T"]}}},{"name":"NODE_0000236","node_attrs":{"div":562,"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C3987T"]}},"children":[{"name":"OQ581855","node_attrs":{"div":565,"accession":"OQ581855","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"C.1"},"country":{"value":"Taiwan"},"strain_display":{"value":"Taiwan/OQ581855/2023-03-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MPXV/human/Taiwan/0310000009/2023"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G15797A","C41168T","A137251T"]}}},{"name":"NODE_0000237","node_attrs":{"div":563,"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C166940T","G193223A"]}},"children":[{"name":"LC756925","node_attrs":{"div":564,"accession":"LC756925","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"C.1"},"country":{"value":"Japan"},"strain_display":{"value":"Japan/LC756925/2023-02-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220342"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-09"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C84734T"]}}},{"name":"LC760460","node_attrs":{"div":565,"accession":"LC760460","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A."},"lineage":{"value":"C.1"},"country":{"value":"Japan"},"strain_display":{"value":"Japan/LC760460/2023-01-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220304"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-23"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G48887A","G75699A"],"OPG096":["R38Q"]},"labels":{"aa":"OPG096: R38Q"}}},{"name":"OR459781","node_attrs":{"div":563,"accession":"OR459781","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"country":{"value":"South Korea"},"strain_display":{"value":"South Korea/OR459781/2023-04-11"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MPXV-ROK-P008-2023"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-04-11"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR427348","node_attrs":{"div":566,"accession":"OR427348","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"C.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR427348/2023-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-066957/2023"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-06-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G26855A","C30191T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C155490T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG047":["R335H"]},"labels":{"aa":"OPG047: R335H"}}},{"name":"OR665166","node_attrs":{"div":568,"accession":"OR665166","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"C.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR665166/2023-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MpxV/human/USA/WA-UW-092809/2023"},"institution":{"value":"UW Virology, Laboratory Medicine"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-09-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T606-","G13434A","G29650A","C33332T","G37974A","C74691T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG025":["R612C"],"OPG046":["T27I"],"OPG050":["R26Q"],"OPG056":["S354L"]},"labels":{"aa":"OPG025: R612C; OPG046: T27I; OPG050: R26Q; OPG056: S354L"}}},{"name":"OR499979","node_attrs":{"div":566,"accession":"OR499979","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"C.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR499979/2023-05-08"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00522/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-05-08"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G11924A","C134237T","G178951A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG023":["S326L"]},"labels":{"aa":"OPG023: S326L"}}},{"name":"NODE_0000238","node_attrs":{"div":565,"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["C149963T","G184562A"],"OPG176":["S52L"]},"labels":{"aa":"OPG176: S52L"}},"children":[{"name":"OR459778","node_attrs":{"div":566,"accession":"OR459778","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"country":{"value":"South Korea"},"strain_display":{"value":"South Korea/OR459778/2023-03-13"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"},"strain":{"value":"MPXV-ROK-P005-2023"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-13"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G85691A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000239","node_attrs":{"div":568,"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-609T","C21062T","G188348A","C188946T"],"OPG036":["M1I"]},"labels":{"aa":"OPG036: M1I"}},"children":[{"name":"OR643705","node_attrs":{"div":574,"accession":"OR643705","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"C.1"},"country":{"value":"USA"},"strain_display":{"value":"USA/OR643705/2023-08-16"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00563/2023"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-08-16"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G21880A","G47532A","C125074T","G133704A","G133838A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T180483A"],"OPG037":["S185F"]},"labels":{"aa":"OPG037: S185F"}}},{"name":"NODE_0000240","node_attrs":{"div":570,"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G101241A","G152866A","C191053-","A191054-","T191055-","G191056-","G191057-","A191058-","G191059-","T191060-","C191061-","G191062-","G191063-","T191064-","A191065-","G191066-","A191067-","T191068-","T191069-","T191070-","C191071-","A191072-","T191073-","G191074-","G191075-","C191076-","T191077-","G191078-","T191079-","C191080-","G191081-","A191082-","T191083-","G191084-","A191085-","G191086-","C191087-","A191088-","G191089-","T191090-","T191091-","T191092-","C191093-","A191094-","C191095-","G191096-","A191097-","C191098-","G191099-","A191100-","C191101-","C191102-","T191103-","C191104-","G191105-","A191106-","T191107-","C191108-","T191109-","T191110-","T191111-","G191112-","G191113-","T191114-","C191115-","A191116-","T191117-","T191118-","A191119-","T191120-","C191121-","T191122-","T191123-","T191124-","G191125-","G191126-","T191127-","A191128-","G191129-"],"OPG180":["D59N"]},"labels":{"aa":"OPG180: D59N"}},"children":[{"name":"OR326996","node_attrs":{"div":570,"accession":"OR326996","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OR326996/2023-06-25"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/PT0632/2023"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-06-25"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T591A","-608T","A196619T"]}}},{"name":"NODE_0000241","node_attrs":{"div":571,"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G13563A"],"OPG025":["P569S"]},"labels":{"aa":"OPG025: P569S"}},"children":[{"name":"OR381842","node_attrs":{"div":573,"accession":"OR381842","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OR381842/2023-07-07"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"Monkeypox/PT0646/2023"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-07-07"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G610-","T611-","C37738T","G151847A"],"OPG056":["E433K"]},"labels":{"aa":"OPG056: E433K"}}},{"name":"OR488000","node_attrs":{"div":574,"accession":"OR488000","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain_display":{"value":"Portugal/OR488000/2023-08-07"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/PT0682/2023"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-08-07"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["G49821A","G87187A","C190352T"],"OPG068":["E541K"],"OPG109":["S754L"]},"labels":{"aa":"OPG068: E541K; OPG109: S754L"}}}]},{"name":"NODE_0000242","node_attrs":{"div":571,"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T607-","T609-","C142797T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"],"OPG164":["S7L"]},"labels":{"aa":"OPG164: S7L"}},"children":[{"name":"OR743500","node_attrs":{"div":573,"accession":"OR743500","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"C.1"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OR743500/2023-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1031"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-10-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{"nuc":["T57476C","G173397A","T179262-","G179263-"],"OPG075":["Q8R"]},"labels":{"aa":"OPG075: Q8R"}}},{"name":"OR519724","node_attrs":{"div":571,"accession":"OR519724","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"C.1"},"country":{"value":"Germany"},"strain_display":{"value":"Germany/OR519724/2023-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1022"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-08-XX"},"outbreak":{"value":"hMPXV-1"}},"branch_attrs":{"mutations":{}}}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}} \ No newline at end of file diff --git a/data_output/nextstrain/mpox/all-clades/unreleased/CHANGELOG.md b/data_output/nextstrain/mpox/all-clades/unreleased/CHANGELOG.md new file mode 100644 index 00000000..919c624d --- /dev/null +++ b/data_output/nextstrain/mpox/all-clades/unreleased/CHANGELOG.md @@ -0,0 +1,13 @@ +## Unreleased + +Initial release of this dataset. This dataset is similar to the v2 dataset [`MPXV/ancestral`](https://github.com/nextstrain/nextclade_data/tree/2023-08-17--15-51-24--UTC/data/datasets/MPXV/references/ancestral/versions/2023-08-01T12%3A00%3A00Z/files) with some differences. + +### New and changed gene names + +Some genes have been renamed and one has been added. The new annotation is based on NCBI refseq annotations that were released in November 2022. The v2 dataset predates this refseq: + +- The 4 genes in the inverted terminal repeat segment (ITR) on both ends of the genome (OPG001, OPG002, OPG003,OPG015) are now all included. The genes on the 3' end (~positions 190000-197000) now have an `_dup` appended to distinguish them. +- The gene previously named `NBT03_gp052` is now called `OPG073` +- The gene previously named `NBT03_gp174` is now called `OPG016` +- The gene previously named `NBT03_gp175` is now called `OPG015_dup` +- Gene `OPG166` has been added diff --git a/data_output/nextstrain/mpox/all-clades/unreleased/README.md b/data_output/nextstrain/mpox/all-clades/unreleased/README.md new file mode 100644 index 00000000..8893afb1 --- /dev/null +++ b/data_output/nextstrain/mpox/all-clades/unreleased/README.md @@ -0,0 +1,23 @@ +# Nextclade dataset for "Mpox virus (All Clades)" + +| Key | Value | +| ---------------------- | --------------------------------------------------------------------------------------------------------------------- | +| authors | [Cornelius Roemer](https://neherlab.org), [Richard Neher](https://neherlab.org), [Nextstrain](https://nextstrain.org) | +| data source | Genbank | +| workflow | [github.com/nextstrain/mpox/nextclade](https://github.com/nextstrain/mpox/nextclade) | +| nextclade dataset path | nextstrain/mpox/all-clades | +| annotation | [NC_063383.1](https://www.ncbi.nlm.nih.gov/nuccore/NC_063383) | +| clade definitions | [github.com/mpxv-lineages/lineage-designation](https://github.com/mpxv-lineages/lineage-designation) | +| related datasets | Mpox virus (Clade IIb): `nextstrain/mpox/clade-iib`
Mpox virus (Lineage B.1) `nextstrain/mpox/lineage-b.1` | + +This dataset is for Mpox viruses of all clades (I, IIa and IIb). For a focused analysis of sequences from clade IIb, you may want to use the more specific dataset: "Clade IIb" (`nextstrain/mpox/clade-iib`). For an even more focused analysis of 2022-2023 outbreak sequences (lineage B.1 and sublineages), you may want to use the even more specific dataset: "Lineage B.1" (`nextstrain/mpox/lineage-b.1`). + +The lineage system used is defined in [Happi et al. (2022)](https://doi.org/10.1371/journal.pbio.3001769). Lineage definitions are available at [github.com/mpxv-lineages/lineage-designation](https://github.com/nextstrain/mpox/nextclade). + +The reference used in this dataset is the clade IIb NCBI refseq `NC_063383.1` (Isolate `MPXV-M5312_HM12_Rivers`). + +The reference tree consists of around 500 sequences with representatives from all clades and lineages. + +## Further reading + +Read more about Nextclade datasets in Nextclade documentation: https://docs.nextstrain.org/projects/nextclade/en/stable/user/datasets.html diff --git a/data_output/nextstrain/mpox/all-clades/unreleased/genome_annotation.gff3 b/data_output/nextstrain/mpox/all-clades/unreleased/genome_annotation.gff3 new file mode 100644 index 00000000..432d5465 --- /dev/null +++ b/data_output/nextstrain/mpox/all-clades/unreleased/genome_annotation.gff3 @@ -0,0 +1,391 @@ +##gff-version 3 +#!gff-spec-version 1.21 +#!processor NCBI annotwriter +##sequence-region NC_063383.1 1 197209 +##species https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10244 +NC_063383.1 RefSeq region 1 197209 . + . ID=NC_063383.1:1..197209;Dbxref=taxon:10244;collection-date=2018-08;country=Nigeria: Rivers State;gbkey=Src;genome=genomic;genotype=MPXV clade 2;isolate=MPXV-M5312_HM12_Rivers;mol_type=genomic DNA;nat-host=Homo sapiens +NC_063383.1 RefSeq long_terminal_repeat 1 6422 . - . ID=id-NC_063383.1:1..6422;gbkey=repeat_region;rpt_type=long_terminal_repeat +NC_063383.1 RefSeq gene 835 1575 . - . ID=gene-NBT03_gp001;Dbxref=GeneID:72551607;Name=OPG001;gbkey=Gene;gene=OPG001;gene_biotype=protein_coding;locus_tag=NBT03_gp001;old_locus_tag=MPXV-M5312_HM12_Rivers-001 +NC_063383.1 RefSeq CDS 835 1575 . - 0 ID=cds-YP_010377002.1;Parent=gene-NBT03_gp001;Dbxref=GenBank:YP_010377002.1,GeneID:72551607;Name=OPG001;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp001%3B Chemokine binding protein (Cop-C23L)%3B most abundant secreted protein%3B CC-chemokine binding%3B similar to VACV-WR J1L and VACV-Cop C23L;gbkey=CDS;gene=OPG001;locus_tag=NBT03_gp001;product=Chemokine binding protein;protein_id=YP_010377002.1 +NC_063383.1 RefSeq gene 1702 2751 . - . ID=gene-NBT03_gp002;Dbxref=GeneID:72551418;Name=OPG002;gbkey=Gene;gene=OPG002;gene_biotype=protein_coding;locus_tag=NBT03_gp002;old_locus_tag=MPXV-M5312_HM12_Rivers-002 +NC_063383.1 RefSeq CDS 1702 2751 . - 0 ID=cds-YP_010377003.1;Parent=gene-NBT03_gp002;Dbxref=GenBank:YP_010377003.1,GeneID:72551418;Name=OPG002;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: NBT03_gp002%3B TNF receptor (CrmB)%3B similar to VACV-WR J2L and VACV-Cop C22L;gbkey=CDS;gene=OPG002;locus_tag=NBT03_gp002;product=Crm-B secreted TNF-alpha-receptor-like protein;protein_id=YP_010377003.1 +NC_063383.1 RefSeq gene 2841 4607 . - . ID=gene-NBT03_gp003;Dbxref=GeneID:72551419;Name=OPG003;gbkey=Gene;gene=OPG003;gene_biotype=protein_coding;locus_tag=NBT03_gp003;old_locus_tag=MPXV-M5312_HM12_Rivers-003 +NC_063383.1 RefSeq CDS 2841 4607 . - 0 ID=cds-YP_010377004.1;Parent=gene-NBT03_gp003;Dbxref=GenBank:YP_010377004.1,GeneID:72551419;Name=OPG003;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp003%3B Ankyrin%3B similar to VACV-WR J3L and VACV-Cop C19L;gbkey=CDS;gene=OPG003;locus_tag=NBT03_gp003;product=Ankyrin repeat protein (25);protein_id=YP_010377004.1 +NC_063383.1 RefSeq gene 4843 6156 . - . ID=gene-NBT03_gp004;Dbxref=GeneID:72551420;Name=OPG015;gbkey=Gene;gene=OPG015;gene_biotype=protein_coding;locus_tag=NBT03_gp004;old_locus_tag=MPXV-M5312_HM12_Rivers-004 +NC_063383.1 RefSeq CDS 4843 6156 . - 0 ID=cds-YP_010377005.1;Parent=gene-NBT03_gp004;Dbxref=GenBank:YP_010377005.1,GeneID:72551420;Name=OPG015;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp004%3B Ankyrin%3B similar to VACV-WR D1L and CPXV-017;gbkey=CDS;gene=OPG015;locus_tag=NBT03_gp004;product=Ankyrin repeat protein (39);protein_id=YP_010377005.1 +NC_063383.1 RefSeq sequence_feature 6270 6419 . - . ID=id-NC_063383.1:6270..6419;exon_number=OPG016;gbkey=misc_feature;number=OPG016 +NC_063383.1 RefSeq sequence_feature 6444 6885 . - . ID=id-NC_063383.1:6444..6885;exon_number=OPG017;gbkey=misc_feature;number=OPG017 +NC_063383.1 RefSeq sequence_feature 6966 7463 . - . ID=id-NC_063383.1:6966..7463;exon_number=OPG018;gbkey=misc_feature;number=OPG018 +NC_063383.1 RefSeq gene 7580 8008 . + . ID=gene-NBT03_gp005;Dbxref=GeneID:72551421;Name=OPG019;gbkey=Gene;gene=OPG019;gene_biotype=protein_coding;locus_tag=NBT03_gp005;old_locus_tag=MPXV-M5312_HM12_Rivers-006 +NC_063383.1 RefSeq CDS 7580 8008 . + 0 ID=cds-YP_010377006.1;Parent=gene-NBT03_gp005;Dbxref=GenBank:YP_010377006.1,GeneID:72551421;Name=OPG019;Note=Taxonomic breadth: chordopoxvirinae%3B secreted growth factor Secreted EGF-like protein%3B similar to VACV-WR D3R and VACV-Cop C11R;gbkey=CDS;gene=OPG019;locus_tag=NBT03_gp005;product=EGF-like domain protein;protein_id=YP_010377006.1 +NC_063383.1 RefSeq sequence_feature 8136 9102 . - . ID=id-NC_063383.1:8136..9102;exon_number=OPG020;gbkey=misc_feature;number=OPG020 +NC_063383.1 RefSeq gene 9587 10315 . + . ID=gene-NBT03_gp006;Dbxref=GeneID:72551422;Name=OPG021;gbkey=Gene;gene=OPG021;gene_biotype=protein_coding;locus_tag=NBT03_gp006;old_locus_tag=MPXV-M5312_HM12_Rivers-008 +NC_063383.1 RefSeq CDS 9587 10315 . + 0 ID=cds-YP_010377007.1;Parent=gene-NBT03_gp006;Dbxref=GenBank:YP_010377007.1,GeneID:72551422;Name=OPG021;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp008%3B Zinc finger-like protein%3B zinc binding%3B virosome localization%3B virulence factor%3B inhibition of apoptosis induced by UV irradiation%3B similar to VACV-WR D5R;gbkey=CDS;gene=OPG021;locus_tag=NBT03_gp006;product=Zinc finger-like protein (2);protein_id=YP_010377007.1 +NC_063383.1 RefSeq gene 10478 10858 . - . ID=gene-NBT03_gp007;Dbxref=GeneID:72551423;Name=OPG022;gbkey=Gene;gene=OPG022;gene_biotype=protein_coding;locus_tag=NBT03_gp007;old_locus_tag=MPXV-M5312_HM12_Rivers-009 +NC_063383.1 RefSeq CDS 10478 10858 . - 0 ID=cds-YP_010377008.1;Parent=gene-NBT03_gp007;Dbxref=GenBank:YP_010377008.1,GeneID:72551423;Name=OPG022;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp009%3B secreted IL-18 binding protein%3B Soluble IL-18 binding protein (Bsh-D7L)%3B similar to VACV-WR D6L;gbkey=CDS;gene=OPG022;locus_tag=NBT03_gp007;product=Interleukin-18-binding protein;protein_id=YP_010377008.1 +NC_063383.1 RefSeq gene 10918 12900 . - . ID=gene-NBT03_gp008;Dbxref=GeneID:72551424;Name=OPG023;gbkey=Gene;gene=OPG023;gene_biotype=protein_coding;locus_tag=NBT03_gp008;old_locus_tag=MPXV-M5312_HM12_Rivers-010 +NC_063383.1 RefSeq CDS 10918 12900 . - 0 ID=cds-YP_010377009.1;Parent=gene-NBT03_gp008;Dbxref=GenBank:YP_010377009.1,GeneID:72551424;Name=OPG023;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp010%3B host range%3B ankyrin-like%3B Ankyrin/Host Range (Bang-D8L)%3B similar to VACV-WR D7L;gbkey=CDS;gene=OPG023;locus_tag=NBT03_gp008;product=Ankyrin repeat protein (2);protein_id=YP_010377009.1 +NC_063383.1 RefSeq gene 13034 13228 . - . ID=gene-NBT03_gp009;Dbxref=GeneID:72551425;Name=OPG024;gbkey=Gene;gene=OPG024;gene_biotype=protein_coding;locus_tag=NBT03_gp009;old_locus_tag=MPXV-M5312_HM12_Rivers-011 +NC_063383.1 RefSeq CDS 13034 13228 . - 0 ID=cds-YP_010377010.1;Parent=gene-NBT03_gp009;Dbxref=GenBank:YP_010377010.1,GeneID:72551425;Name=OPG024;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp011%3B ANK-containing protein%3B similar to VACV-WR D8L;gbkey=CDS;gene=OPG024;locus_tag=NBT03_gp009;product=retroviral pseudoprotease-like protein;protein_id=YP_010377010.1 +NC_063383.1 RefSeq gene 13375 15267 . - . ID=gene-NBT03_gp010;Dbxref=GeneID:72551426;Name=OPG025;gbkey=Gene;gene=OPG025;gene_biotype=protein_coding;locus_tag=NBT03_gp010;old_locus_tag=MPXV-M5312_HM12_Rivers-012 +NC_063383.1 RefSeq CDS 13375 15267 . - 0 ID=cds-YP_010377011.1;Parent=gene-NBT03_gp010;Dbxref=GenBank:YP_010377011.1,GeneID:72551426;Name=OPG025;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp012%3B ankyrin-like%3B Type I IFN resistance%3B similar to VACV-WR D9L and VACV-Cop C9L;gbkey=CDS;gene=OPG025;locus_tag=NBT03_gp010;product=Ankyrin repeat protein (14);protein_id=YP_010377011.1 +NC_063383.1 RefSeq sequence_feature 15310 15854 . - . ID=id-NC_063383.1:15310..15854;exon_number=OPG026;gbkey=misc_feature;number=OPG026 +NC_063383.1 RefSeq gene 15925 16377 . - . ID=gene-NBT03_gp011;Dbxref=GeneID:72551427;Name=OPG027;gbkey=Gene;gene=OPG027;gene_biotype=protein_coding;locus_tag=NBT03_gp011;old_locus_tag=MPXV-M5312_HM12_Rivers-013 +NC_063383.1 RefSeq CDS 15925 16377 . - 0 ID=cds-YP_010377012.1;Parent=gene-NBT03_gp011;Dbxref=GenBank:YP_010377012.1,GeneID:72551427;Name=OPG027;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp013%3B host range%3B Type 1 IFN inhibitor%3B similar to VACV-WR D10L and VACV-Cop C7L;gbkey=CDS;gene=OPG027;locus_tag=NBT03_gp011;product=Host range protein;protein_id=YP_010377012.1 +NC_063383.1 RefSeq gene 16602 17069 . - . ID=gene-NBT03_gp012;Dbxref=GeneID:72551428;Name=OPG029;gbkey=Gene;gene=OPG029;gene_biotype=protein_coding;locus_tag=NBT03_gp012;old_locus_tag=MPXV-M5312_HM12_Rivers-014 +NC_063383.1 RefSeq CDS 16602 17069 . - 0 ID=cds-YP_010377013.1;Parent=gene-NBT03_gp012;Dbxref=GenBank:YP_010377013.1,GeneID:72551428;Name=OPG029;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp014%3B Putative tlr signaling inhibitor%2C IFN-beta inhibitor%3B similar to VACV-WR D11L and VACV-Cop C6L;gbkey=CDS;gene=OPG029;locus_tag=NBT03_gp012;product=Bcl-2-like protein;protein_id=YP_010377013.1 +NC_063383.1 RefSeq gene 17213 17833 . - . ID=gene-NBT03_gp013;Dbxref=GeneID:72551429;Name=OPG030;gbkey=Gene;gene=OPG030;gene_biotype=protein_coding;locus_tag=NBT03_gp013;old_locus_tag=MPXV-M5312_HM12_Rivers-015 +NC_063383.1 RefSeq CDS 17213 17833 . - 0 ID=cds-YP_010377014.1;Parent=gene-NBT03_gp013;Dbxref=GenBank:YP_010377014.1,GeneID:72551429;Name=OPG030;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp015%3B BTB domain of kelch-like protein%3B Kelch-like protein%3B similar to VACV-WR D12L and VACV-Cop C5L;gbkey=CDS;gene=OPG030;locus_tag=NBT03_gp013;product=Kelch-like protein (1);protein_id=YP_010377014.1 +NC_063383.1 RefSeq gene 17878 18828 . - . ID=gene-NBT03_gp014;Dbxref=GeneID:72551430;Name=OPG031;gbkey=Gene;gene=OPG031;gene_biotype=protein_coding;locus_tag=NBT03_gp014;old_locus_tag=MPXV-M5312_HM12_Rivers-016 +NC_063383.1 RefSeq CDS 17878 18828 . - 0 ID=cds-YP_010377015.1;Parent=gene-NBT03_gp014;Dbxref=GenBank:YP_010377015.1,GeneID:72551430;Name=OPG031;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp016%3B IL-1 receptor antagonist%3B similar to VACV-WR D13L and VACV-Cop C10L;gbkey=CDS;gene=OPG031;locus_tag=NBT03_gp014;product=C4L/C10L-like family protein;protein_id=YP_010377015.1 +NC_063383.1 RefSeq sequence_feature 18902 19288 . - . ID=id-NC_063383.1:18902..19288;exon_number=OPG033;gbkey=misc_feature;number=OPG033 +NC_063383.1 RefSeq gene 19361 20005 . - . ID=gene-NBT03_gp015;Dbxref=GeneID:72551431;Name=OPG034;gbkey=Gene;gene=OPG034;gene_biotype=protein_coding;locus_tag=NBT03_gp015;old_locus_tag=MPXV-M5312_HM12_Rivers-018 +NC_063383.1 RefSeq CDS 19361 20005 . - 0 ID=cds-YP_010377017.1;Parent=gene-NBT03_gp015;Dbxref=GenBank:YP_010377017.1,GeneID:72551431;Name=OPG034;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp022%3B Putative TLR signalling inhibitor%3B start of ORF is missing approx. 18 AA compared to CPXVs%3B similar to VACV-WR D19L and VACV-Cop C1L;gbkey=CDS;gene=OPG034;locus_tag=NBT03_gp015;product=Bcl-2-like protein;protein_id=YP_010377017.1 +NC_063383.1 RefSeq gene 20051 20404 . - . ID=gene-NBT03_gp016;Dbxref=GeneID:72551432;Name=OPG035;gbkey=Gene;gene=OPG035;gene_biotype=protein_coding;locus_tag=NBT03_gp016;old_locus_tag=MPXV-M5312_HM12_Rivers-019 +NC_063383.1 RefSeq CDS 20051 20404 . - 0 ID=cds-YP_010377018.1;Parent=gene-NBT03_gp016;Dbxref=GenBank:YP_010377018.1,GeneID:72551432;Name=OPG035;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp023%3B secreted virulence factor%3B Putative tlr signaling inhibitor%3B Anti-apoptotic Bcl-2-like protein%3B similar to VACV-WR P1L and VACV-Cop N1L;gbkey=CDS;gene=OPG035;locus_tag=NBT03_gp016;product=Bcl-2-like protein;protein_id=YP_010377018.1 +NC_063383.1 RefSeq gene 20531 21064 . - . ID=gene-NBT03_gp017;Dbxref=GeneID:72551433;Name=OPG036;gbkey=Gene;gene=OPG036;gene_biotype=protein_coding;locus_tag=NBT03_gp017;old_locus_tag=MPXV-M5312_HM12_Rivers-020 +NC_063383.1 RefSeq CDS 20531 21064 . - 0 ID=cds-YP_010377019.1;Parent=gene-NBT03_gp017;Dbxref=GenBank:YP_010377019.1,GeneID:72551433;Name=OPG036;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp024%3B Alpha amanatin target protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR P2L and VACV-Cop #N2L;gbkey=CDS;gene=OPG036;locus_tag=NBT03_gp017;product=Bcl-2-like protein;protein_id=YP_010377019.1 +NC_063383.1 RefSeq gene 21105 22433 . - . ID=gene-NBT03_gp018;Dbxref=GeneID:72551434;Name=OPG037;gbkey=Gene;gene=OPG037;gene_biotype=protein_coding;locus_tag=NBT03_gp018;old_locus_tag=MPXV-M5312_HM12_Rivers-021 +NC_063383.1 RefSeq CDS 21105 22433 . - 0 ID=cds-YP_010377020.1;Parent=gene-NBT03_gp018;Dbxref=GenBank:YP_010377020.1,GeneID:72551434;Name=OPG037;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp025%3B ankyrin-like%3B ANK-containing protein%3B apoptosis inhibitor%3B start of ORF is missing approx. 31 AA compared to CPXVs%3B similar to VACV-WR O1L and VACV-Cop M1L;gbkey=CDS;gene=OPG037;locus_tag=NBT03_gp018;product=Ankyrin-like protein (1);protein_id=YP_010377020.1 +NC_063383.1 RefSeq gene 22497 23159 . - . ID=gene-NBT03_gp019;Dbxref=GeneID:72551435;Name=OPG038;gbkey=Gene;gene=OPG038;gene_biotype=protein_coding;locus_tag=NBT03_gp019;old_locus_tag=MPXV-M5312_HM12_Rivers-022 +NC_063383.1 RefSeq CDS 22497 23159 . - 0 ID=cds-YP_010377021.1;Parent=gene-NBT03_gp019;Dbxref=GenBank:YP_010377021.1,GeneID:72551435;Name=OPG038;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp026%3B NFkB inhibitor%3B similar to VACV-WR O2L and VACV-Cop M2L;gbkey=CDS;gene=OPG038;locus_tag=NBT03_gp019;product=NFkB inhibitor;protein_id=YP_010377021.1 +NC_063383.1 RefSeq gene 23264 24118 . - . ID=gene-NBT03_gp020;Dbxref=GeneID:72551436;Name=OPG039;gbkey=Gene;gene=OPG039;gene_biotype=protein_coding;locus_tag=NBT03_gp020;old_locus_tag=MPXV-M5312_HM12_Rivers-023 +NC_063383.1 RefSeq CDS 23264 24118 . - 0 ID=cds-YP_010377022.1;Parent=gene-NBT03_gp020;Dbxref=GenBank:YP_010377022.1,GeneID:72551436;Name=OPG039;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp027%3B host range%3B ankyrin-like%3B Ankyrin/NFkB inhibitor%3B similar to VACV-WR C1L and VACV-Cop K1L;gbkey=CDS;gene=OPG039;locus_tag=NBT03_gp020;product=Ankyrin-like protein (3);protein_id=YP_010377022.1 +NC_063383.1 RefSeq gene 24351 25478 . - . ID=gene-NBT03_gp021;Dbxref=GeneID:72551437;Name=OPG040;gbkey=Gene;gene=OPG040;gene_biotype=protein_coding;locus_tag=NBT03_gp021;old_locus_tag=MPXV-M5312_HM12_Rivers-024 +NC_063383.1 RefSeq CDS 24351 25478 . - 0 ID=cds-YP_010377023.1;Parent=gene-NBT03_gp021;Dbxref=GenBank:YP_010377023.1,GeneID:72551437;Name=OPG040;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp028%3B serine protease inhibitor-like%2C SPI-3%3B inhibition of the ability of infected cells to fuse%3B Serpin 1%2C2%2C3%3B similar to VACV-WR C2L and VACV-Cop K2L;gbkey=CDS;gene=OPG040;locus_tag=NBT03_gp021;product=Serpin;protein_id=YP_010377023.1 +NC_063383.1 RefSeq sequence_feature 25529 25767 . - . ID=id-NC_063383.1:25529..25767;exon_number=OPG041;gbkey=misc_feature;number=OPG041 +NC_063383.1 RefSeq gene 25823 27097 . - . ID=gene-NBT03_gp022;Dbxref=GeneID:72551438;Name=OPG042;gbkey=Gene;gene=OPG042;gene_biotype=protein_coding;locus_tag=NBT03_gp022;old_locus_tag=MPXV-M5312_HM12_Rivers-026 +NC_063383.1 RefSeq CDS 25823 27097 . - 0 ID=cds-YP_010377025.1;Parent=gene-NBT03_gp022;Dbxref=GenBank:YP_010377025.1,GeneID:72551438;Name=OPG042;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp030%3B phospholipase D-like%3B Phospholipase-D-like protein%3B similar to VACV-WR C4L and VACV-Cop K4L;gbkey=CDS;gene=OPG042;locus_tag=NBT03_gp022;product=Phospholipase-D-like protein;protein_id=YP_010377025.1 +NC_063383.1 RefSeq gene 27125 27955 . - . ID=gene-NBT03_gp023;Dbxref=GeneID:72551439;Name=OPG043;gbkey=Gene;gene=OPG043;gene_biotype=protein_coding;locus_tag=NBT03_gp023;old_locus_tag=MPXV-M5312_HM12_Rivers-027 +NC_063383.1 RefSeq CDS 27125 27955 . - 0 ID=cds-YP_010377026.1;Parent=gene-NBT03_gp023;Dbxref=GenBank:YP_010377026.1,GeneID:72551439;Name=OPG043;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp031%3B lysophospholipase-like%3B Monoglyceride lipase%3B similar to VACV-WR C5L and VACV-Cop K5L;gbkey=CDS;gene=OPG043;locus_tag=NBT03_gp023;product=Putative monoglyceride lipase;protein_id=YP_010377026.1 +NC_063383.1 RefSeq gene 28091 28540 . + . ID=gene-NBT03_gp024;Dbxref=GeneID:72551440;Name=OPG044;gbkey=Gene;gene=OPG044;gene_biotype=protein_coding;locus_tag=NBT03_gp024;old_locus_tag=MPXV-M5312_HM12_Rivers-028 +NC_063383.1 RefSeq CDS 28091 28540 . + 0 ID=cds-YP_010377027.1;Parent=gene-NBT03_gp024;Dbxref=GenBank:YP_010377027.1,GeneID:72551440;Name=OPG044;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp032%3B Putative tlr signaling inhibitor%3B Host immune response repressor%3B similar to VACV-WR C6R and VACV-Cop #K7R;gbkey=CDS;gene=OPG044;locus_tag=NBT03_gp024;product=Bcl-2-like protein;protein_id=YP_010377027.1 +NC_063383.1 RefSeq gene 28603 29262 . - . ID=gene-NBT03_gp025;Dbxref=GeneID:72551441;Name=OPG045;gbkey=Gene;gene=OPG045;gene_biotype=protein_coding;locus_tag=NBT03_gp025;old_locus_tag=MPXV-M5312_HM12_Rivers-029 +NC_063383.1 RefSeq CDS 28603 29262 . - 0 ID=cds-YP_010377028.1;Parent=gene-NBT03_gp025;Dbxref=GenBank:YP_010377028.1,GeneID:72551441;Name=OPG045;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp033%3B Caspase-9 (apoptosis) inhibitor (mitochondrial- associated)%3B similar to VACV-WR C7L and VACV-Cop F1L;gbkey=CDS;gene=OPG045;locus_tag=NBT03_gp025;product=Caspase-9 inhibitor;protein_id=YP_010377028.1 +NC_063383.1 RefSeq gene 29274 29729 . - . ID=gene-NBT03_gp026;Dbxref=GeneID:72551442;Name=OPG046;gbkey=Gene;gene=OPG046;gene_biotype=protein_coding;locus_tag=NBT03_gp026;old_locus_tag=MPXV-M5312_HM12_Rivers-030 +NC_063383.1 RefSeq CDS 29274 29729 . - 0 ID=cds-YP_010377029.1;Parent=gene-NBT03_gp026;Dbxref=GenBank:YP_010377029.1,GeneID:72551442;Name=OPG046;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp034%3B deoxyuridine triphosphatase%3B dUTPase%3B similar to VACV-WR C8L and VACV-Cop F2L;gbkey=CDS;gene=OPG046;locus_tag=NBT03_gp026;product=dUTPase;protein_id=YP_010377029.1 +NC_063383.1 RefSeq gene 29746 31194 . - . ID=gene-NBT03_gp027;Dbxref=GeneID:72551443;Name=OPG047;gbkey=Gene;gene=OPG047;gene_biotype=protein_coding;locus_tag=NBT03_gp027;old_locus_tag=MPXV-M5312_HM12_Rivers-031 +NC_063383.1 RefSeq CDS 29746 31194 . - 0 ID=cds-YP_010377030.1;Parent=gene-NBT03_gp027;Dbxref=GenBank:YP_010377030.1,GeneID:72551443;Name=OPG047;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp035%3B kelch-like%3B Kelch-like protein%3B similar to VACV-WR C9L and VACV-Cop F3L;gbkey=CDS;gene=OPG047;locus_tag=NBT03_gp027;product=Kelch-like protein (2);protein_id=YP_010377030.1 +NC_063383.1 RefSeq gene 31205 32164 . - . ID=gene-NBT03_gp028;Dbxref=GeneID:72551444;Name=OPG048;gbkey=Gene;gene=OPG048;gene_biotype=protein_coding;locus_tag=NBT03_gp028;old_locus_tag=MPXV-M5312_HM12_Rivers-032 +NC_063383.1 RefSeq CDS 31205 32164 . - 0 ID=cds-YP_010377031.1;Parent=gene-NBT03_gp028;Dbxref=GenBank:YP_010377031.1,GeneID:72551444;Name=OPG048;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp036%3B Ribonucleotide reductase small subunit%2C R2%3B similar to VACV-WR C10L and VACV-Cop F4L;gbkey=CDS;gene=OPG048;locus_tag=NBT03_gp028;product=Ribonucleotide reductase small subunit;protein_id=YP_010377031.1 +NC_063383.1 RefSeq gene 32195 33151 . - . ID=gene-NBT03_gp029;Dbxref=GeneID:72551445;Name=OPG049;gbkey=Gene;gene=OPG049;gene_biotype=protein_coding;locus_tag=NBT03_gp029;old_locus_tag=MPXV-M5312_HM12_Rivers-033 +NC_063383.1 RefSeq CDS 32195 33151 . - 0 ID=cds-YP_010377032.1;Parent=gene-NBT03_gp029;Dbxref=GenBank:YP_010377032.1,GeneID:72551445;Name=OPG049;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp037%3B 36kDa major membrane protein%3B similar to VACV-WR C11L and VACV-Cop F5L;gbkey=CDS;gene=OPG049;locus_tag=NBT03_gp029;product=Telomere-binding protein I6 (1);protein_id=YP_010377032.1 +NC_063383.1 RefSeq gene 33181 33408 . - . ID=gene-NBT03_gp030;Dbxref=GeneID:72551446;Name=OPG050;gbkey=Gene;gene=OPG050;gene_biotype=protein_coding;locus_tag=NBT03_gp030;old_locus_tag=MPXV-M5312_HM12_Rivers-034 +NC_063383.1 RefSeq CDS 33181 33408 . - 0 ID=cds-YP_010377033.1;Parent=gene-NBT03_gp030;Dbxref=GenBank:YP_010377033.1,GeneID:72551446;Name=OPG050;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp038%3B Hypothetical protein%3B similar to VACV-WR C12L and VACV-Cop F6L;gbkey=CDS;gene=OPG050;locus_tag=NBT03_gp030;product=CPXV053 protein;protein_id=YP_010377033.1 +NC_063383.1 RefSeq gene 33425 33649 . - . ID=gene-NBT03_gp031;Dbxref=GeneID:72551447;Name=OPG051;gbkey=Gene;gene=OPG051;gene_biotype=protein_coding;locus_tag=NBT03_gp031;old_locus_tag=MPXV-M5312_HM12_Rivers-035 +NC_063383.1 RefSeq CDS 33425 33649 . - 0 ID=cds-YP_010377034.1;Parent=gene-NBT03_gp031;Dbxref=GenBank:YP_010377034.1,GeneID:72551447;Name=OPG051;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp039%3B Hypothetical protein%3B similar to VACV-WR C13L and VACV-Cop F7L;gbkey=CDS;gene=OPG051;locus_tag=NBT03_gp031;product=CPXV054 protein;protein_id=YP_010377034.1 +NC_063383.1 RefSeq gene 33801 33995 . - . ID=gene-NBT03_gp032;Dbxref=GeneID:72551448;Name=OPG052;gbkey=Gene;gene=OPG052;gene_biotype=protein_coding;locus_tag=NBT03_gp032;old_locus_tag=MPXV-M5312_HM12_Rivers-036 +NC_063383.1 RefSeq CDS 33801 33995 . - 0 ID=cds-YP_010377035.1;Parent=gene-NBT03_gp032;Dbxref=GenBank:YP_010377035.1,GeneID:72551448;Name=OPG052;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp040%3B Cytoplasmic protein%3B similar to VACV-WR C14L and VACV-Cop F8L;gbkey=CDS;gene=OPG052;locus_tag=NBT03_gp032;product=Cytoplasmic protein;protein_id=YP_010377035.1 +NC_063383.1 RefSeq gene 34052 34690 . - . ID=gene-NBT03_gp033;Dbxref=GeneID:72551449;Name=OPG053;gbkey=Gene;gene=OPG053;gene_biotype=protein_coding;locus_tag=NBT03_gp033;old_locus_tag=MPXV-M5312_HM12_Rivers-037 +NC_063383.1 RefSeq CDS 34052 34690 . - 0 ID=cds-YP_010377036.1;Parent=gene-NBT03_gp033;Dbxref=GenBank:YP_010377036.1,GeneID:72551449;Name=OPG053;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp041%3B S-S bond formation pathway protein substrate%3B similar to VACV-WR C15L and VACV-Cop F9L;gbkey=CDS;gene=OPG053;locus_tag=NBT03_gp033;product=IMV membrane protein L1R;protein_id=YP_010377036.1 +NC_063383.1 RefSeq gene 34677 35996 . - . ID=gene-NBT03_gp034;Dbxref=GeneID:72551450;Name=OPG054;gbkey=Gene;gene=OPG054;gene_biotype=protein_coding;locus_tag=NBT03_gp034;old_locus_tag=MPXV-M5312_HM12_Rivers-038 +NC_063383.1 RefSeq CDS 34677 35996 . - 0 ID=cds-YP_010377037.1;Parent=gene-NBT03_gp034;Dbxref=GenBank:YP_010377037.1,GeneID:72551450;Name=OPG054;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp042%3B serine%3B Essential Ser/Thr kinase morph%3B similar to VACV-WR C16L and VACV-Cop F10L;gbkey=CDS;gene=OPG054;locus_tag=NBT03_gp034;product=Serine/threonine-protein kinase;protein_id=YP_010377037.1 +NC_063383.1 RefSeq gene 36019 37083 . - . ID=gene-NBT03_gp035;Dbxref=GeneID:72551451;Name=OPG055;gbkey=Gene;gene=OPG055;gene_biotype=protein_coding;locus_tag=NBT03_gp035;old_locus_tag=MPXV-M5312_HM12_Rivers-039 +NC_063383.1 RefSeq CDS 36019 37083 . - 0 ID=cds-YP_010377038.1;Parent=gene-NBT03_gp035;Dbxref=GenBank:YP_010377038.1,GeneID:72551451;Name=OPG055;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp043%3B RhoA signalling inhibitor%2C virus release protein%3B MC018%3B similar to VACV-WR C17L and VACV-Cop F11L;gbkey=CDS;gene=OPG055;locus_tag=NBT03_gp035;product=Protein F11;protein_id=YP_010377038.1 +NC_063383.1 RefSeq gene 37127 39034 . - . ID=gene-NBT03_gp036;Dbxref=GeneID:72551452;Name=OPG056;gbkey=Gene;gene=OPG056;gene_biotype=protein_coding;locus_tag=NBT03_gp036;old_locus_tag=MPXV-M5312_HM12_Rivers-040 +NC_063383.1 RefSeq CDS 37127 39034 . - 0 ID=cds-YP_010377039.1;Parent=gene-NBT03_gp036;Dbxref=GenBank:YP_010377039.1,GeneID:72551452;Name=OPG056;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp044%3B actin tail formation%3B EEV maturation protein%3B similar to VACV-WR C18L and VACV-Cop F12L;gbkey=CDS;gene=OPG056;locus_tag=NBT03_gp036;product=EEV maturation protein;protein_id=YP_010377039.1 +NC_063383.1 RefSeq gene 39077 40195 . - . ID=gene-NBT03_gp037;Dbxref=GeneID:72551453;Name=OPG057;gbkey=Gene;gene=OPG057;gene_biotype=protein_coding;locus_tag=NBT03_gp037;old_locus_tag=MPXV-M5312_HM12_Rivers-041 +NC_063383.1 RefSeq CDS 39077 40195 . - 0 ID=cds-YP_010377040.1;Parent=gene-NBT03_gp037;Dbxref=GenBank:YP_010377040.1,GeneID:72551453;Name=OPG057;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp045%3B major envelope antigen of EEV%3B wrapping of IMV to form IEV%3B phospholipase D-like%3B Palmitylated EEV membrane glycoprotein%3B similar to VACV-WR C19L and VACV-Cop F13L;gbkey=CDS;gene=OPG057;locus_tag=NBT03_gp037;product=Palmytilated EEV membrane protein;protein_id=YP_010377040.1 +NC_063383.1 RefSeq gene 40213 40434 . - . ID=gene-NBT03_gp038;Dbxref=GeneID:72551454;Name=OPG058;gbkey=Gene;gene=OPG058;gene_biotype=protein_coding;locus_tag=NBT03_gp038;old_locus_tag=MPXV-M5312_HM12_Rivers-042 +NC_063383.1 RefSeq CDS 40213 40434 . - 0 ID=cds-YP_010377041.1;Parent=gene-NBT03_gp038;Dbxref=GenBank:YP_010377041.1,GeneID:72551454;Name=OPG058;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp046%3B similar to VACV-WR C20L and VACV-Cop F14L;gbkey=CDS;gene=OPG058;locus_tag=NBT03_gp038;product=Protein F14 (1);protein_id=YP_010377041.1 +NC_063383.1 RefSeq gene 40484 40633 . - . ID=gene-NBT03_gp039;Dbxref=GeneID:72551455;Name=OPG059;gbkey=Gene;gene=OPG059;gene_biotype=protein_coding;locus_tag=NBT03_gp039;old_locus_tag=MPXV-M5312_HM12_Rivers-043 +NC_063383.1 RefSeq CDS 40484 40633 . - 0 ID=cds-YP_010377042.1;Parent=gene-NBT03_gp039;Dbxref=GenBank:YP_010377042.1,GeneID:72551455;Name=OPG059;Note=Taxonomic breadth: poxvirinae%3B IMV protein%3B C20.5L%3B similar to VACV-CopF14.5L;gbkey=CDS;gene=OPG059;locus_tag=NBT03_gp039;product=Cytochrome C oxidase;protein_id=YP_010377042.1 +NC_063383.1 RefSeq gene 40706 41182 . - . ID=gene-NBT03_gp040;Dbxref=GeneID:72551456;Name=OPG060;gbkey=Gene;gene=OPG060;gene_biotype=protein_coding;locus_tag=NBT03_gp040;old_locus_tag=MPXV-M5312_HM12_Rivers-044 +NC_063383.1 RefSeq CDS 40706 41182 . - 0 ID=cds-YP_010377043.1;Parent=gene-NBT03_gp040;Dbxref=GenBank:YP_010377043.1,GeneID:72551456;Name=OPG060;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp047%3B Unknown conserved protein%3B similar to VACV-WR C21L and VACV-Cop F15L;gbkey=CDS;gene=OPG060;locus_tag=NBT03_gp040;product=Protein F15;protein_id=YP_010377043.1 +NC_063383.1 RefSeq gene 41189 41884 . - . ID=gene-NBT03_gp041;Dbxref=GeneID:72551457;Name=OPG061;gbkey=Gene;gene=OPG061;gene_biotype=protein_coding;locus_tag=NBT03_gp041;old_locus_tag=MPXV-M5312_HM12_Rivers-045 +NC_063383.1 RefSeq CDS 41189 41884 . - 0 ID=cds-YP_010377044.1;Parent=gene-NBT03_gp041;Dbxref=GenBank:YP_010377044.1,GeneID:72551457;Name=OPG061;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp048%3B Non-functional Serine Recombinase%3B similar to VACV-WR C22L and VACV-Cop F16L;gbkey=CDS;gene=OPG061;locus_tag=NBT03_gp041;product=Protein F16 (1);protein_id=YP_010377044.1 +NC_063383.1 RefSeq gene 41947 42252 . + . ID=gene-NBT03_gp042;Dbxref=GeneID:72551458;Name=OPG062;gbkey=Gene;gene=OPG062;gene_biotype=protein_coding;locus_tag=NBT03_gp042;old_locus_tag=MPXV-M5312_HM12_Rivers-046 +NC_063383.1 RefSeq CDS 41947 42252 . + 0 ID=cds-YP_010377045.1;Parent=gene-NBT03_gp042;Dbxref=GenBank:YP_010377045.1,GeneID:72551458;Name=OPG062;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp049%3B virion core DNA-binding phosphoprotein (VP11)%3B mTOR antagonist%3B similar to VACV-WR C23R and VACV-Cop F17R;gbkey=CDS;gene=OPG062;locus_tag=NBT03_gp042;product=DNA-binding phosphoprotein (1);protein_id=YP_010377045.1 +NC_063383.1 RefSeq gene 42249 43688 . - . ID=gene-NBT03_gp043;Dbxref=GeneID:72551459;Name=OPG063;gbkey=Gene;gene=OPG063;gene_biotype=protein_coding;locus_tag=NBT03_gp043;old_locus_tag=MPXV-M5312_HM12_Rivers-047 +NC_063383.1 RefSeq CDS 42249 43688 . - 0 ID=cds-YP_010377046.1;Parent=gene-NBT03_gp043;Dbxref=GenBank:YP_010377046.1,GeneID:72551459;Name=OPG063;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp050%3B poly-A polymerase%2C Poly (A) polymerase catalytic subunit (VP55)%3B similar to VACV-WR F1L and VACV-Cop E1L;gbkey=CDS;gene=OPG063;locus_tag=NBT03_gp043;product=Poly(A) polymerase catalytic subunit (3);protein_id=YP_010377046.1 +NC_063383.1 RefSeq gene 43685 45898 . - . ID=gene-NBT03_gp044;Dbxref=GeneID:72551460;Name=OPG064;gbkey=Gene;gene=OPG064;gene_biotype=protein_coding;locus_tag=NBT03_gp044;old_locus_tag=MPXV-M5312_HM12_Rivers-048 +NC_063383.1 RefSeq CDS 43685 45898 . - 0 ID=cds-YP_010377047.1;Parent=gene-NBT03_gp044;Dbxref=GenBank:YP_010377047.1,GeneID:72551460;Name=OPG064;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp051%3B IEV morphogenesis%3B similar to VACV-WR F2L and VACV-Cop E2L;gbkey=CDS;gene=OPG064;locus_tag=NBT03_gp044;product=Iev morphogenesis protein;protein_id=YP_010377047.1 +NC_063383.1 RefSeq gene 46022 46483 . - . ID=gene-NBT03_gp045;Dbxref=GeneID:72551461;Name=OPG065;gbkey=Gene;gene=OPG065;gene_biotype=protein_coding;locus_tag=NBT03_gp045;old_locus_tag=MPXV-M5312_HM12_Rivers-049 +NC_063383.1 RefSeq CDS 46022 46483 . - 0 ID=cds-YP_010377048.1;Parent=gene-NBT03_gp045;Dbxref=GenBank:YP_010377048.1,GeneID:72551461;Name=OPG065;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp052%3B interferon resistance factor%3B two forms (25 kDa and 19 kDa) of the dsRNA-binding protein%3B inhibition of dsRNA-dependent protein kinase and 2-5A-synthet%3B dsRNA-binding protein%2C IFN resistance/PKR inhibitor (Z-DNA binding)%3B start of ORF is missing approx. 37 AA compared to CPXVs%3B similar to VACV-WR F3L and VACV-Cop E3L;gbkey=CDS;gene=OPG065;locus_tag=NBT03_gp045;product=Double-stranded RNA binding protein;protein_id=YP_010377048.1 +NC_063383.1 RefSeq gene 46649 47428 . - . ID=gene-NBT03_gp046;Dbxref=GeneID:72551462;Name=OPG066;gbkey=Gene;gene=OPG066;gene_biotype=protein_coding;locus_tag=NBT03_gp046;old_locus_tag=MPXV-M5312_HM12_Rivers-050 +NC_063383.1 RefSeq CDS 46649 47428 . - 0 ID=cds-YP_010377049.1;Parent=gene-NBT03_gp046;Dbxref=GenBank:YP_010377049.1,GeneID:72551462;Name=OPG066;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp053%3B RNA polymerase 30 kDa subunit (RPO30)%3B simultaneously intermediate stage promoter-specific transcription factor%2C VITF-1%3B similar to VACV-WR F4L and VACV-Cop E4L;gbkey=CDS;gene=OPG066;locus_tag=NBT03_gp046;product=DNA-directed RNA polymerase 30 kDa polypeptide;protein_id=YP_010377049.1 +NC_063383.1 RefSeq sequence_feature 47525 48062 . + . ID=id-NC_063383.1:47525..48062;exon_number=OPG067;gbkey=misc_feature;number=OPG067 +NC_063383.1 RefSeq gene 48201 49904 . + . ID=gene-NBT03_gp047;Dbxref=GeneID:72551463;Name=OPG068;gbkey=Gene;gene=OPG068;gene_biotype=protein_coding;locus_tag=NBT03_gp047;old_locus_tag=MPXV-M5312_HM12_Rivers-052 +NC_063383.1 RefSeq CDS 48201 49904 . + 0 ID=cds-YP_010377051.1;Parent=gene-NBT03_gp047;Dbxref=GenBank:YP_010377051.1,GeneID:72551463;Name=OPG068;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp054%3B Virion protein%3B similar to VACV-WR F5R and VACV-Cop E6R;gbkey=CDS;gene=OPG068;locus_tag=NBT03_gp047;product=IMV membrane protein E6;protein_id=YP_010377051.1 +NC_063383.1 RefSeq gene 49986 50486 . + . ID=gene-NBT03_gp048;Dbxref=GeneID:72551464;Name=OPG069;gbkey=Gene;gene=OPG069;gene_biotype=protein_coding;locus_tag=NBT03_gp048;old_locus_tag=MPXV-M5312_HM12_Rivers-053 +NC_063383.1 RefSeq CDS 49986 50486 . + 0 ID=cds-YP_010377052.1;Parent=gene-NBT03_gp048;Dbxref=GenBank:YP_010377052.1,GeneID:72551464;Name=OPG069;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp055%3B soluble myristylated protein%3B similar to VACV-WR F6R and VACV-Cop E7R;gbkey=CDS;gene=OPG069;locus_tag=NBT03_gp048;product=Myristoylated protein E7;protein_id=YP_010377052.1 +NC_063383.1 RefSeq gene 50590 51411 . + . ID=gene-NBT03_gp049;Dbxref=GeneID:72551465;Name=OPG070;gbkey=Gene;gene=OPG070;gene_biotype=protein_coding;locus_tag=NBT03_gp049;old_locus_tag=MPXV-M5312_HM12_Rivers-054 +NC_063383.1 RefSeq CDS 50590 51411 . + 0 ID=cds-YP_010377053.1;Parent=gene-NBT03_gp049;Dbxref=GenBank:YP_010377053.1,GeneID:72551465;Name=OPG070;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp056%3B ER-localized membrane protein%2C virion core protein%3B similar to VACV-WR F7R and VACV-Cop E8R;gbkey=CDS;gene=OPG070;locus_tag=NBT03_gp049;product=Membrane protein E8;protein_id=YP_010377053.1 +NC_063383.1 RefSeq gene 51418 54438 . - . ID=gene-NBT03_gp050;Dbxref=GeneID:72551466;Name=OPG071;gbkey=Gene;gene=OPG071;gene_biotype=protein_coding;locus_tag=NBT03_gp050;old_locus_tag=MPXV-M5312_HM12_Rivers-055 +NC_063383.1 RefSeq CDS 51418 54438 . - 0 ID=cds-YP_010377054.1;Parent=gene-NBT03_gp050;Dbxref=GenBank:YP_010377054.1,GeneID:72551466;Name=OPG071;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp057%3B DNA polymerase%2C catalytic subunit%3B similar to VACV-WR F8L and VACV-Cop E9L;gbkey=CDS;gene=OPG071;locus_tag=NBT03_gp050;product=DNA polymerase (2);protein_id=YP_010377054.1 +NC_063383.1 RefSeq gene 54470 54757 . + . ID=gene-NBT03_gp051;Dbxref=GeneID:72551467;Name=OPG072;gbkey=Gene;gene=OPG072;gene_biotype=protein_coding;locus_tag=NBT03_gp051;old_locus_tag=MPXV-M5312_HM12_Rivers-056 +NC_063383.1 RefSeq CDS 54470 54757 . + 0 ID=cds-YP_010377055.1;Parent=gene-NBT03_gp051;Dbxref=GenBank:YP_010377055.1,GeneID:72551467;Name=OPG072;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp058%3B protein disulfide bond-forming enzyme%3B Sulfhydryl oxidase (FAD-linked)%3B similar to VACV-WR F9R and VACV-Cop E10R;gbkey=CDS;gene=OPG072;locus_tag=NBT03_gp051;product=Sulfhydryl oxidase;protein_id=YP_010377055.1 +NC_063383.1 RefSeq gene 54752 55141 . - . ID=gene-NBT03_gp052;Dbxref=GeneID:72551468;Name=OPG073;gbkey=Gene;gene=OPG073;gene_biotype=protein_coding;locus_tag=NBT03_gp052;old_locus_tag=MPXV-M5312_HM12_Rivers-057 +NC_063383.1 RefSeq CDS 54752 55141 . - 0 ID=cds-YP_010377056.1;Parent=gene-NBT03_gp052;Dbxref=GenBank:YP_010377056.1,GeneID:72551468;Name=OPG073;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp059%3B virion core protein%3B similar to VACV-WR F10L and VACV-Cop E11L;gbkey=CDS;gene=OPG073;locus_tag=NBT03_gp052;product=Virion core protein E11;protein_id=YP_010377056.1 +NC_063383.1 RefSeq gene 55128 57125 . - . ID=gene-NBT03_gp053;Dbxref=GeneID:72551469;Name=OPG074;gbkey=Gene;gene=OPG074;gene_biotype=protein_coding;locus_tag=NBT03_gp053;old_locus_tag=MPXV-M5312_HM12_Rivers-058 +NC_063383.1 RefSeq CDS 55128 57125 . - 0 ID=cds-YP_010377057.1;Parent=gene-NBT03_gp053;Dbxref=GenBank:YP_010377057.1,GeneID:72551469;Name=OPG074;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp060%3B Membrane protein%3B similar to VACV-WR Q1L and VACV-Cop O1L;gbkey=CDS;gene=OPG074;locus_tag=NBT03_gp053;product=Iev morphogenesis protein;protein_id=YP_010377057.1 +NC_063383.1 RefSeq gene 57172 57498 . - . ID=gene-NBT03_gp054;Dbxref=GeneID:72551470;Name=OPG075;gbkey=Gene;gene=OPG075;gene_biotype=protein_coding;locus_tag=NBT03_gp054;old_locus_tag=MPXV-M5312_HM12_Rivers-059 +NC_063383.1 RefSeq CDS 57172 57498 . - 0 ID=cds-YP_010377058.1;Parent=gene-NBT03_gp054;Dbxref=GenBank:YP_010377058.1,GeneID:72551470;Name=OPG075;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp061%3B virion-associated glutaredoxin%3B glutaredoxin 1%3B similar to VACV-WR Q2L and VACV-Cop O2L;gbkey=CDS;gene=OPG075;locus_tag=NBT03_gp054;product=Glutaredoxin-1;protein_id=YP_010377058.1 +NC_063383.1 RefSeq gene 57523 57630 . - . ID=gene-NBT03_gp055;Dbxref=GeneID:72551471;Name=OPG076;gbkey=Gene;gene=OPG076;gene_biotype=protein_coding;locus_tag=NBT03_gp055 +NC_063383.1 RefSeq CDS 57523 57630 . - 0 ID=cds-YP_010377183.1;Parent=gene-NBT03_gp055;Dbxref=GenBank:YP_010377183.1,GeneID:72551471;Name=OPG076;gbkey=CDS;gene=OPG076;locus_tag=NBT03_gp055;product=MV membrane EFC component;protein_id=YP_010377183.1 +NC_063383.1 RefSeq gene 57645 58583 . - . ID=gene-NBT03_gp056;Dbxref=GeneID:72551472;Name=OPG077;gbkey=Gene;gene=OPG077;gene_biotype=protein_coding;locus_tag=NBT03_gp056;old_locus_tag=MPXV-M5312_HM12_Rivers-060 +NC_063383.1 RefSeq CDS 57645 58583 . - 0 ID=cds-YP_010377059.1;Parent=gene-NBT03_gp056;Dbxref=GenBank:YP_010377059.1,GeneID:72551472;Name=OPG077;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp062%3B virosomal protein essential for virus multiplication%3B DNA-binding core protein%3B similar to VACV-WR I1L and VACV-Cop I1L;gbkey=CDS;gene=OPG077;locus_tag=NBT03_gp056;product=Telomere-binding protein I1;protein_id=YP_010377059.1 +NC_063383.1 RefSeq gene 58590 58811 . - . ID=gene-NBT03_gp057;Dbxref=GeneID:72551473;Name=OPG078;gbkey=Gene;gene=OPG078;gene_biotype=protein_coding;locus_tag=NBT03_gp057;old_locus_tag=MPXV-M5312_HM12_Rivers-061 +NC_063383.1 RefSeq CDS 58590 58811 . - 0 ID=cds-YP_010377060.1;Parent=gene-NBT03_gp057;Dbxref=GenBank:YP_010377060.1,GeneID:72551473;Name=OPG078;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp063%3B IMV membrane protein%3B similar to VACV-WR I2L and VACV-Cop I2L;gbkey=CDS;gene=OPG078;locus_tag=NBT03_gp057;product=IMV membrane protein I2;protein_id=YP_010377060.1 +NC_063383.1 RefSeq gene 58812 59621 . - . ID=gene-NBT03_gp058;Dbxref=GeneID:72551474;Name=OPG079;gbkey=Gene;gene=OPG079;gene_biotype=protein_coding;locus_tag=NBT03_gp058;old_locus_tag=MPXV-M5312_HM12_Rivers-062 +NC_063383.1 RefSeq CDS 58812 59621 . - 0 ID=cds-YP_010377061.1;Parent=gene-NBT03_gp058;Dbxref=GenBank:YP_010377061.1,GeneID:72551474;Name=OPG079;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp064%3B virosomal ssDNA-binding phosphoprotein%3B interacts with R2 subunit of ribonucleotide reductase%3B similar to VACV-WR I3L and VACV-Cop I3L;gbkey=CDS;gene=OPG079;locus_tag=NBT03_gp058;product=DNA-binding phosphoprotein (2);protein_id=YP_010377061.1 +NC_063383.1 RefSeq gene 59703 62018 . - . ID=gene-NBT03_gp059;Dbxref=GeneID:72551475;Name=OPG080;gbkey=Gene;gene=OPG080;gene_biotype=protein_coding;locus_tag=NBT03_gp059;old_locus_tag=MPXV-M5312_HM12_Rivers-063 +NC_063383.1 RefSeq CDS 59703 62018 . - 0 ID=cds-YP_010377062.1;Parent=gene-NBT03_gp059;Dbxref=GenBank:YP_010377062.1,GeneID:72551475;Name=OPG080;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp065%3B ribonucleotide reductase%2C large subunit%2C R1%3B similar to VACV-WR I4L and VACV-Cop I4L;gbkey=CDS;gene=OPG080;locus_tag=NBT03_gp059;product=Ribonucleoside-diphosphate reductase (2);protein_id=YP_010377062.1 +NC_063383.1 RefSeq gene 62046 62285 . - . ID=gene-NBT03_gp060;Dbxref=GeneID:72551476;Name=OPG081;gbkey=Gene;gene=OPG081;gene_biotype=protein_coding;locus_tag=NBT03_gp060;old_locus_tag=MPXV-M5312_HM12_Rivers-064 +NC_063383.1 RefSeq CDS 62046 62285 . - 0 ID=cds-YP_010377063.1;Parent=gene-NBT03_gp060;Dbxref=GenBank:YP_010377063.1,GeneID:72551476;Name=OPG081;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp066%3B IMV surface membrane protein%2C VP13%3B similar to VACV-WR I5L and VACV-Cop I5L;gbkey=CDS;gene=OPG081;locus_tag=NBT03_gp060;product=IMV membrane protein I5;protein_id=YP_010377063.1 +NC_063383.1 RefSeq gene 62304 63452 . - . ID=gene-NBT03_gp061;Dbxref=GeneID:72551477;Name=OPG082;gbkey=Gene;gene=OPG082;gene_biotype=protein_coding;locus_tag=NBT03_gp061;old_locus_tag=MPXV-M5312_HM12_Rivers-065 +NC_063383.1 RefSeq CDS 62304 63452 . - 0 ID=cds-YP_010377064.1;Parent=gene-NBT03_gp061;Dbxref=GenBank:YP_010377064.1,GeneID:72551477;Name=OPG082;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp067%3B Telomere-binding protein%3B similar to VACV-WR I6L and VACV-Cop I6L;gbkey=CDS;gene=OPG082;locus_tag=NBT03_gp061;product=Telomere-binding protein;protein_id=YP_010377064.1 +NC_063383.1 RefSeq gene 63445 64716 . - . ID=gene-NBT03_gp062;Dbxref=GeneID:72551478;Name=OPG083;gbkey=Gene;gene=OPG083;gene_biotype=protein_coding;locus_tag=NBT03_gp062;old_locus_tag=MPXV-M5312_HM12_Rivers-066 +NC_063383.1 RefSeq CDS 63445 64716 . - 0 ID=cds-YP_010377065.1;Parent=gene-NBT03_gp062;Dbxref=GenBank:YP_010377065.1,GeneID:72551478;Name=OPG083;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp068%3B virion core protein%3B similar to DNA topoisomerase II%3B Virion core cysteine protease%3B similar to VACV-WR I7L and VACV-Cop I7L;gbkey=CDS;gene=OPG083;locus_tag=NBT03_gp062;product=Viral core cysteine proteinase;protein_id=YP_010377065.1 +NC_063383.1 RefSeq gene 64722 66752 . + . ID=gene-NBT03_gp063;Dbxref=GeneID:72551479;Name=OPG084;gbkey=Gene;gene=OPG084;gene_biotype=protein_coding;locus_tag=NBT03_gp063;old_locus_tag=MPXV-M5312_HM12_Rivers-067 +NC_063383.1 RefSeq CDS 64722 66752 . + 0 ID=cds-YP_010377066.1;Parent=gene-NBT03_gp063;Dbxref=GenBank:YP_010377066.1,GeneID:72551479;Name=OPG084;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp069%3B nucleoside triphosphate phosphohydrolase II%2C NPH-II%3B DNA and RNA helicase%3B DExH-NPH-II domain%3B similar to VACV-WR I8R and VACV-Cop I8R;gbkey=CDS;gene=OPG084;locus_tag=NBT03_gp063;product=RNA helicase NPH-II (2);protein_id=YP_010377066.1 +NC_063383.1 RefSeq gene 66756 68531 . - . ID=gene-NBT03_gp064;Dbxref=GeneID:72551480;Name=OPG085;gbkey=Gene;gene=OPG085;gene_biotype=protein_coding;locus_tag=NBT03_gp064;old_locus_tag=MPXV-M5312_HM12_Rivers-068 +NC_063383.1 RefSeq CDS 66756 68531 . - 0 ID=cds-YP_010377067.1;Parent=gene-NBT03_gp064;Dbxref=GenBank:YP_010377067.1,GeneID:72551480;Name=OPG085;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp070%3B proteinase%3B Metalloprotease%3B similar to VACV-WR G1L and VACV-Cop G1L;gbkey=CDS;gene=OPG085;locus_tag=NBT03_gp064;product=Metalloendopeptidase;protein_id=YP_010377067.1 +NC_063383.1 RefSeq gene 68528 68863 . - . ID=gene-NBT03_gp065;Dbxref=GeneID:72551481;Name=OPG086;gbkey=Gene;gene=OPG086;gene_biotype=protein_coding;locus_tag=NBT03_gp065;old_locus_tag=MPXV-M5312_HM12_Rivers-069 +NC_063383.1 RefSeq CDS 68528 68863 . - 0 ID=cds-YP_010377068.1;Parent=gene-NBT03_gp065;Dbxref=GenBank:YP_010377068.1,GeneID:72551481;Name=OPG086;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp071%3B Entry/fusion complex component%3B similar to VACV-WR G2L and VACV-Cop G3L;gbkey=CDS;gene=OPG086;locus_tag=NBT03_gp065;product=Entry/fusion complex component;protein_id=YP_010377068.1 +NC_063383.1 RefSeq gene 68857 69519 . + . ID=gene-NBT03_gp066;Dbxref=GeneID:72551482;Name=OPG087;gbkey=Gene;gene=OPG087;gene_biotype=protein_coding;locus_tag=NBT03_gp066;old_locus_tag=MPXV-M5312_HM12_Rivers-070 +NC_063383.1 RefSeq CDS 68857 69519 . + 0 ID=cds-YP_010377069.1;Parent=gene-NBT03_gp066;Dbxref=GenBank:YP_010377069.1,GeneID:72551482;Name=OPG087;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp072%3B VLTF (late transcription elongation factor)%3B similar to VACV-WR G3R and VACV-Cop G2R;gbkey=CDS;gene=OPG087;locus_tag=NBT03_gp066;product=Late transcription elongation factor;protein_id=YP_010377069.1 +NC_063383.1 RefSeq gene 69489 69863 . - . ID=gene-NBT03_gp067;Dbxref=GeneID:72551483;Name=OPG088;gbkey=Gene;gene=OPG088;gene_biotype=protein_coding;locus_tag=NBT03_gp067;old_locus_tag=MPXV-M5312_HM12_Rivers-071 +NC_063383.1 RefSeq CDS 69489 69863 . - 0 ID=cds-YP_010377070.1;Parent=gene-NBT03_gp067;Dbxref=GenBank:YP_010377070.1,GeneID:72551483;Name=OPG088;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp073%3B virion-associated glutaredoxin%3B Glutaredoxin-like protein%3B similar to VACV-WR G4L and VACV-Cop G4L;gbkey=CDS;gene=OPG088;locus_tag=NBT03_gp067;product=Glutaredoxin-2;protein_id=YP_010377070.1 +NC_063383.1 RefSeq gene 69866 71170 . + . ID=gene-NBT03_gp068;Dbxref=GeneID:72551484;Name=OPG089;gbkey=Gene;gene=OPG089;gene_biotype=protein_coding;locus_tag=NBT03_gp068;old_locus_tag=MPXV-M5312_HM12_Rivers-072 +NC_063383.1 RefSeq CDS 69866 71170 . + 0 ID=cds-YP_010377071.1;Parent=gene-NBT03_gp068;Dbxref=GenBank:YP_010377071.1,GeneID:72551484;Name=OPG089;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp074%3B FEN1-like nuclease%3B similar to VACV-WR G5R and VACV-Cop G5R;gbkey=CDS;gene=OPG089;locus_tag=NBT03_gp068;product=FEN1-like nuclease;protein_id=YP_010377071.1 +NC_063383.1 RefSeq gene 71179 71370 . + . ID=gene-NBT03_gp069;Dbxref=GeneID:72551485;Name=OPG090;gbkey=Gene;gene=OPG090;gene_biotype=protein_coding;locus_tag=NBT03_gp069;old_locus_tag=MPXV-M5312_HM12_Rivers-073 +NC_063383.1 RefSeq CDS 71179 71370 . + 0 ID=cds-YP_010377072.1;Parent=gene-NBT03_gp069;Dbxref=GenBank:YP_010377072.1,GeneID:72551485;Name=OPG090;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp075%3B RNA polymerase subunit%2C 7 kDa subunit (RPO7)%3B similar to VACV-WR G6R and VACV-Cop G5.5R;gbkey=CDS;gene=OPG090;locus_tag=NBT03_gp069;product=DNA-directed RNA polymerase 7 kDa subunit;protein_id=YP_010377072.1 +NC_063383.1 RefSeq gene 71370 71867 . + . ID=gene-NBT03_gp070;Dbxref=GeneID:72551486;Name=OPG091;gbkey=Gene;gene=OPG091;gene_biotype=protein_coding;locus_tag=NBT03_gp070;old_locus_tag=MPXV-M5312_HM12_Rivers-074 +NC_063383.1 RefSeq CDS 71370 71867 . + 0 ID=cds-YP_010377073.1;Parent=gene-NBT03_gp070;Dbxref=GenBank:YP_010377073.1,GeneID:72551486;Name=OPG091;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp076%3B NLPc/P60 superfamily protein%3B similar to VACV-WR G7R and VACV-Cop G6R;gbkey=CDS;gene=OPG091;locus_tag=NBT03_gp070;product=Nlpc/p60 superfamily protein;protein_id=YP_010377073.1 +NC_063383.1 RefSeq gene 71832 72947 . - . ID=gene-NBT03_gp071;Dbxref=GeneID:72551487;Name=OPG092;gbkey=Gene;gene=OPG092;gene_biotype=protein_coding;locus_tag=NBT03_gp071;old_locus_tag=MPXV-M5312_HM12_Rivers-075 +NC_063383.1 RefSeq CDS 71832 72947 . - 0 ID=cds-YP_010377074.1;Parent=gene-NBT03_gp071;Dbxref=GenBank:YP_010377074.1,GeneID:72551487;Name=OPG092;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp077%3B virion protein%3B Virion phosphoprotein%2C early morphogenesis%3B similar to VACV-WR G8L and VACV-Cop G7L;gbkey=CDS;gene=OPG092;locus_tag=NBT03_gp071;product=Assembly protein G7;protein_id=YP_010377074.1 +NC_063383.1 RefSeq gene 72978 73760 . + . ID=gene-NBT03_gp072;Dbxref=GeneID:72551488;Name=OPG093;gbkey=Gene;gene=OPG093;gene_biotype=protein_coding;locus_tag=NBT03_gp072;old_locus_tag=MPXV-M5312_HM12_Rivers-076 +NC_063383.1 RefSeq CDS 72978 73760 . + 0 ID=cds-YP_010377075.1;Parent=gene-NBT03_gp072;Dbxref=GenBank:YP_010377075.1,GeneID:72551488;Name=OPG093;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp078%3B late gene transcription factor%2C VLTF-1%3B similar to VACV-WR G9R and VACV-Cop G8R;gbkey=CDS;gene=OPG093;locus_tag=NBT03_gp072;product=Late transcription factor VLTF-1;protein_id=YP_010377075.1 +NC_063383.1 RefSeq gene 73780 74802 . + . ID=gene-NBT03_gp073;Dbxref=GeneID:72551489;Name=OPG094;gbkey=Gene;gene=OPG094;gene_biotype=protein_coding;locus_tag=NBT03_gp073;old_locus_tag=MPXV-M5312_HM12_Rivers-077 +NC_063383.1 RefSeq CDS 73780 74802 . + 0 ID=cds-YP_010377076.1;Parent=gene-NBT03_gp073;Dbxref=GenBank:YP_010377076.1,GeneID:72551489;Name=OPG094;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp079%3B myristylated protein%3B Entry/fusion complex component%2C myristylprotein%3B similar to VACV-WR G10R and VACV-Cop G9R;gbkey=CDS;gene=OPG094;locus_tag=NBT03_gp073;product=Myristylated protein;protein_id=YP_010377076.1 +NC_063383.1 RefSeq gene 74803 75555 . + . ID=gene-NBT03_gp074;Dbxref=GeneID:72551490;Name=OPG095;gbkey=Gene;gene=OPG095;gene_biotype=protein_coding;locus_tag=NBT03_gp074;old_locus_tag=MPXV-M5312_HM12_Rivers-078 +NC_063383.1 RefSeq CDS 74803 75555 . + 0 ID=cds-YP_010377077.1;Parent=gene-NBT03_gp074;Dbxref=GenBank:YP_010377077.1,GeneID:72551490;Name=OPG095;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp080%3B myristylated IMV surface membrane protein%3B similar to VACV-WR M1R and VACV-Cop L1R;gbkey=CDS;gene=OPG095;locus_tag=NBT03_gp074;product=IMV membrane protein L1R;protein_id=YP_010377077.1 +NC_063383.1 RefSeq gene 75587 75865 . + . ID=gene-NBT03_gp075;Dbxref=GeneID:72551491;Name=OPG096;gbkey=Gene;gene=OPG096;gene_biotype=protein_coding;locus_tag=NBT03_gp075;old_locus_tag=MPXV-M5312_HM12_Rivers-079 +NC_063383.1 RefSeq CDS 75587 75865 . + 0 ID=cds-YP_010377078.1;Parent=gene-NBT03_gp075;Dbxref=GenBank:YP_010377078.1,GeneID:72551491;Name=OPG096;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp081%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR M2R and VACV-Cop L2R;gbkey=CDS;gene=OPG096;locus_tag=NBT03_gp075;product=Crescent membrane and immature virion formation protein;protein_id=YP_010377078.1 +NC_063383.1 RefSeq gene 75841 76875 . - . ID=gene-NBT03_gp076;Dbxref=GeneID:72551492;Name=OPG097;gbkey=Gene;gene=OPG097;gene_biotype=protein_coding;locus_tag=NBT03_gp076;old_locus_tag=MPXV-M5312_HM12_Rivers-080 +NC_063383.1 RefSeq CDS 75841 76875 . - 0 ID=cds-YP_010377079.1;Parent=gene-NBT03_gp076;Dbxref=GenBank:YP_010377079.1,GeneID:72551492;Name=OPG097;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp082%3B Internal virion protein%3B similar to VACV-WR M3L and VACV-Cop L3L;gbkey=CDS;gene=OPG097;locus_tag=NBT03_gp076;product=Internal virion L3/FP4 protein;protein_id=YP_010377079.1 +NC_063383.1 RefSeq gene 76900 77655 . + . ID=gene-NBT03_gp077;Dbxref=GeneID:72551493;Name=OPG098;gbkey=Gene;gene=OPG098;gene_biotype=protein_coding;locus_tag=NBT03_gp077;old_locus_tag=MPXV-M5312_HM12_Rivers-081 +NC_063383.1 RefSeq CDS 76900 77655 . + 0 ID=cds-YP_010377080.1;Parent=gene-NBT03_gp077;Dbxref=GenBank:YP_010377080.1,GeneID:72551493;Name=OPG098;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp083%3B virion core protein vp8%3B stimulation of I8R helicase activity%3B ss/dsDNA binding protein (VP8)%3B similar to VACV-WR M4R and VACV-Cop L4R;gbkey=CDS;gene=OPG098;locus_tag=NBT03_gp077;product=Nucleic acid binding protein VP8/L4R;protein_id=YP_010377080.1 +NC_063383.1 RefSeq gene 77665 78051 . + . ID=gene-NBT03_gp078;Dbxref=GeneID:72551494;Name=OPG099;gbkey=Gene;gene=OPG099;gene_biotype=protein_coding;locus_tag=NBT03_gp078;old_locus_tag=MPXV-M5312_HM12_Rivers-082 +NC_063383.1 RefSeq CDS 77665 78051 . + 0 ID=cds-YP_010377081.1;Parent=gene-NBT03_gp078;Dbxref=GenBank:YP_010377081.1,GeneID:72551494;Name=OPG099;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp084%3B Entry and Fusion IMV protein%3B similar to VACV-WR M5R and VACV-Cop L5R;gbkey=CDS;gene=OPG099;locus_tag=NBT03_gp078;product=Membrane protein CL5;protein_id=YP_010377081.1 +NC_063383.1 RefSeq gene 78008 78466 . + . ID=gene-NBT03_gp079;Dbxref=GeneID:72551495;Name=OPG100;gbkey=Gene;gene=OPG100;gene_biotype=protein_coding;locus_tag=NBT03_gp079;old_locus_tag=MPXV-M5312_HM12_Rivers-083 +NC_063383.1 RefSeq CDS 78008 78466 . + 0 ID=cds-YP_010377082.1;Parent=gene-NBT03_gp079;Dbxref=GenBank:YP_010377082.1,GeneID:72551495;Name=OPG100;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp085%3B Virion morph%3B similar to VACV-WR L1R and VACV-Cop J1R;gbkey=CDS;gene=OPG100;locus_tag=NBT03_gp079;product=IMV membrane protein J1;protein_id=YP_010377082.1 +NC_063383.1 RefSeq gene 78486 79019 . + . ID=gene-NBT03_gp080;Dbxref=GeneID:72551496;Name=OPG101;gbkey=Gene;gene=OPG101;gene_biotype=protein_coding;locus_tag=NBT03_gp080;old_locus_tag=MPXV-M5312_HM12_Rivers-084 +NC_063383.1 RefSeq CDS 78486 79019 . + 0 ID=cds-YP_010377083.1;Parent=gene-NBT03_gp080;Dbxref=GenBank:YP_010377083.1,GeneID:72551496;Name=OPG101;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp086%3B thymidine kinase%3B similar to VACV-WR L2R and VACV-Cop J2R;gbkey=CDS;gene=OPG101;locus_tag=NBT03_gp080;product=Thymidine kinase;protein_id=YP_010377083.1 +NC_063383.1 RefSeq gene 79085 80086 . + . ID=gene-NBT03_gp081;Dbxref=GeneID:72551497;Name=OPG102;gbkey=Gene;gene=OPG102;gene_biotype=protein_coding;locus_tag=NBT03_gp081;old_locus_tag=MPXV-M5312_HM12_Rivers-085 +NC_063383.1 RefSeq CDS 79085 80086 . + 0 ID=cds-YP_010377084.1;Parent=gene-NBT03_gp081;Dbxref=GenBank:YP_010377084.1,GeneID:72551497;Name=OPG102;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp087%3B poly-A polymerase%2C stimulatory subunit%2C simultaneously cap-specific mRNA (nucleoside-O2'-)-methyltransferase%3B Poly (A) polymerase small subunit (VP39)%3B similar to VACV-WR L3R and VACV-Cop J3R;gbkey=CDS;gene=OPG102;locus_tag=NBT03_gp081;product=Cap-specific mRNA;protein_id=YP_010377084.1 +NC_063383.1 RefSeq gene 80001 80558 . + . ID=gene-NBT03_gp082;Dbxref=GeneID:72551498;Name=OPG103;gbkey=Gene;gene=OPG103;gene_biotype=protein_coding;locus_tag=NBT03_gp082;old_locus_tag=MPXV-M5312_HM12_Rivers-086 +NC_063383.1 RefSeq CDS 80001 80558 . + 0 ID=cds-YP_010377085.1;Parent=gene-NBT03_gp082;Dbxref=GenBank:YP_010377085.1,GeneID:72551498;Name=OPG103;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp088%3B RNA polymerase%2C 22 kDa subunit (RPO22)%3B similar to VACV-WR L4R and VACV-Cop J4R;gbkey=CDS;gene=OPG103;locus_tag=NBT03_gp082;product=DNA-directed RNA polymerase subunit;protein_id=YP_010377085.1 +NC_063383.1 RefSeq gene 80618 81019 . - . ID=gene-NBT03_gp083;Dbxref=GeneID:72551499;Name=OPG104;gbkey=Gene;gene=OPG104;gene_biotype=protein_coding;locus_tag=NBT03_gp083;old_locus_tag=MPXV-M5312_HM12_Rivers-087 +NC_063383.1 RefSeq CDS 80618 81019 . - 0 ID=cds-YP_010377086.1;Parent=gene-NBT03_gp083;Dbxref=GenBank:YP_010377086.1,GeneID:72551499;Name=OPG104;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp089%3B essential for virus multiplication%3B IMV membrane protein%3B similar to VACV-WR L5L and VACV-Cop J5L;gbkey=CDS;gene=OPG104;locus_tag=NBT03_gp083;product=Myristylated protein;protein_id=YP_010377086.1 +NC_063383.1 RefSeq gene 81126 84986 . + . ID=gene-NBT03_gp084;Dbxref=GeneID:72551500;Name=OPG105;gbkey=Gene;gene=OPG105;gene_biotype=protein_coding;locus_tag=NBT03_gp084;old_locus_tag=MPXV-M5312_HM12_Rivers-088 +NC_063383.1 RefSeq CDS 81126 84986 . + 0 ID=cds-YP_010377087.1;Parent=gene-NBT03_gp084;Dbxref=GenBank:YP_010377087.1,GeneID:72551500;Name=OPG105;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp090%3B RNA polymerase%2C 147 kDa subunit (RPO147)%3B similar to VACV-WR L6R and VACV-Cop J6R;gbkey=CDS;gene=OPG105;locus_tag=NBT03_gp084;product=DNA-dependent RNA polymerase subunit rpo147;protein_id=YP_010377087.1 +NC_063383.1 RefSeq gene 84983 85498 . - . ID=gene-NBT03_gp085;Dbxref=GeneID:72551501;Name=OPG106;gbkey=Gene;gene=OPG106;gene_biotype=protein_coding;locus_tag=NBT03_gp085;old_locus_tag=MPXV-M5312_HM12_Rivers-089 +NC_063383.1 RefSeq CDS 84983 85498 . - 0 ID=cds-YP_010377088.1;Parent=gene-NBT03_gp085;Dbxref=GenBank:YP_010377088.1,GeneID:72551501;Name=OPG106;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp091%3B tyrosine%3B Tyr/Ser phosphatase%2C IFN-gamma inhibitor%3B similar to VACV-WR H1L and VACV-Cop H1L;gbkey=CDS;gene=OPG106;locus_tag=NBT03_gp085;product=Tyr/ser protein phosphatase;protein_id=YP_010377088.1 +NC_063383.1 RefSeq gene 85512 86081 . + . ID=gene-NBT03_gp086;Dbxref=GeneID:72551502;Name=OPG107;gbkey=Gene;gene=OPG107;gene_biotype=protein_coding;locus_tag=NBT03_gp086;old_locus_tag=MPXV-M5312_HM12_Rivers-090 +NC_063383.1 RefSeq CDS 85512 86081 . + 0 ID=cds-YP_010377089.1;Parent=gene-NBT03_gp086;Dbxref=GenBank:YP_010377089.1,GeneID:72551502;Name=OPG107;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp092%3B IMV membrane protein%3B similar to VACV-WR H2R and VACV-Cop H2R;gbkey=CDS;gene=OPG107;locus_tag=NBT03_gp086;product=Entry-fusion complex essential component;protein_id=YP_010377089.1 +NC_063383.1 RefSeq gene 86085 87059 . - . ID=gene-NBT03_gp087;Dbxref=GeneID:72551503;Name=OPG108;gbkey=Gene;gene=OPG108;gene_biotype=protein_coding;locus_tag=NBT03_gp087;old_locus_tag=MPXV-M5312_HM12_Rivers-091 +NC_063383.1 RefSeq CDS 86085 87059 . - 0 ID=cds-YP_010377090.1;Parent=gene-NBT03_gp087;Dbxref=GenBank:YP_010377090.1,GeneID:72551503;Name=OPG108;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp093%3B IMV surface membrane protein%3B IMV heparin binding surface protein%3B similar to VACV-WR H3L and VACV-Cop H3L;gbkey=CDS;gene=OPG108;locus_tag=NBT03_gp087;product=IMV heparin binding surface protein;protein_id=YP_010377090.1 +NC_063383.1 RefSeq gene 87060 89447 . - . ID=gene-NBT03_gp088;Dbxref=GeneID:72551504;Name=OPG109;gbkey=Gene;gene=OPG109;gene_biotype=protein_coding;locus_tag=NBT03_gp088;old_locus_tag=MPXV-M5312_HM12_Rivers-092 +NC_063383.1 RefSeq CDS 87060 89447 . - 0 ID=cds-YP_010377091.1;Parent=gene-NBT03_gp088;Dbxref=GenBank:YP_010377091.1,GeneID:72551504;Name=OPG109;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp094%3B virion core RNA polymerase-associated protein%2C RAP94%3B similar to VACV-WR H4L and VACV-Cop H4L;gbkey=CDS;gene=OPG109;locus_tag=NBT03_gp088;product=RNA polymerase-associated transcription-specificity factor RAP94;protein_id=YP_010377091.1 +NC_063383.1 RefSeq gene 89632 90264 . + . ID=gene-NBT03_gp089;Dbxref=GeneID:72551505;Name=OPG110;gbkey=Gene;gene=OPG110;gene_biotype=protein_coding;locus_tag=NBT03_gp089;old_locus_tag=MPXV-M5312_HM12_Rivers-093 +NC_063383.1 RefSeq CDS 89632 90264 . + 0 ID=cds-YP_010377092.1;Parent=gene-NBT03_gp089;Dbxref=GenBank:YP_010377092.1,GeneID:72551505;Name=OPG110;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp095%3B virosome-associated late gene transcription factor%2C VLTF-4%3B Ca2+-binding motif%3B similar to VACV-WR H5R and VACV-Cop H5R;gbkey=CDS;gene=OPG110;locus_tag=NBT03_gp089;product=Late transcription factor VLTF-4 (1);protein_id=YP_010377092.1 +NC_063383.1 RefSeq gene 90265 91209 . + . ID=gene-NBT03_gp090;Dbxref=GeneID:72551506;Name=OPG111;gbkey=Gene;gene=OPG111;gene_biotype=protein_coding;locus_tag=NBT03_gp090;old_locus_tag=MPXV-M5312_HM12_Rivers-094 +NC_063383.1 RefSeq CDS 90265 91209 . + 0 ID=cds-YP_010377093.1;Parent=gene-NBT03_gp090;Dbxref=GenBank:YP_010377093.1,GeneID:72551506;Name=OPG111;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp096%3B DNA topoisomerase type I%3B similar to VACV-WR H6R and VACV-Cop H6R;gbkey=CDS;gene=OPG111;locus_tag=NBT03_gp090;product=DNA topoisomerase type I;protein_id=YP_010377093.1 +NC_063383.1 RefSeq gene 91247 91687 . + . ID=gene-NBT03_gp091;Dbxref=GeneID:72551507;Name=OPG112;gbkey=Gene;gene=OPG112;gene_biotype=protein_coding;locus_tag=NBT03_gp091;old_locus_tag=MPXV-M5312_HM12_Rivers-095 +NC_063383.1 RefSeq CDS 91247 91687 . + 0 ID=cds-YP_010377094.1;Parent=gene-NBT03_gp091;Dbxref=GenBank:YP_010377094.1,GeneID:72551507;Name=OPG112;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp097%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR H7R and VACV-Cop H7R;gbkey=CDS;gene=OPG112;locus_tag=NBT03_gp091;product=Late protein H7;protein_id=YP_010377094.1 +NC_063383.1 RefSeq gene 91731 94268 . + . ID=gene-NBT03_gp092;Dbxref=GeneID:72551508;Name=OPG113;gbkey=Gene;gene=OPG113;gene_biotype=protein_coding;locus_tag=NBT03_gp092;old_locus_tag=MPXV-M5312_HM12_Rivers-096 +NC_063383.1 RefSeq CDS 91731 94268 . + 0 ID=cds-YP_010377095.1;Parent=gene-NBT03_gp092;Dbxref=GenBank:YP_010377095.1,GeneID:72551508;Name=OPG113;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp098%3B mRNA capping enzyme%2C large subunit%3B RNA 5' triphosphatase and RNA guanylyl transferase activities%3B similar to VACV-WR E1R and VACV-Cop D1R;gbkey=CDS;gene=OPG113;locus_tag=NBT03_gp092;product=mRNA capping enzyme large subunit;protein_id=YP_010377095.1 +NC_063383.1 RefSeq gene 94227 94667 . - . ID=gene-NBT03_gp093;Dbxref=GeneID:72551509;Name=OPG114;gbkey=Gene;gene=OPG114;gene_biotype=protein_coding;locus_tag=NBT03_gp093;old_locus_tag=MPXV-M5312_HM12_Rivers-097 +NC_063383.1 RefSeq CDS 94227 94667 . - 0 ID=cds-YP_010377096.1;Parent=gene-NBT03_gp093;Dbxref=GenBank:YP_010377096.1,GeneID:72551509;Name=OPG114;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp099%3B virion core protein%3B similar to VACV-WR E2L and VACV-Cop D2L;gbkey=CDS;gene=OPG114;locus_tag=NBT03_gp093;product=Virion protein D2;protein_id=YP_010377096.1 +NC_063383.1 RefSeq gene 94660 95361 . + . ID=gene-NBT03_gp094;Dbxref=GeneID:72551510;Name=OPG115;gbkey=Gene;gene=OPG115;gene_biotype=protein_coding;locus_tag=NBT03_gp094;old_locus_tag=MPXV-M5312_HM12_Rivers-098 +NC_063383.1 RefSeq CDS 94660 95361 . + 0 ID=cds-YP_010377097.1;Parent=gene-NBT03_gp094;Dbxref=GenBank:YP_010377097.1,GeneID:72551510;Name=OPG115;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp100%3B virion core protein%3B similar to VACV-WR E3R and VACV-Cop D3R;gbkey=CDS;gene=OPG115;locus_tag=NBT03_gp094;product=Virion core protein D3;protein_id=YP_010377097.1 +NC_063383.1 RefSeq gene 95361 96017 . + . ID=gene-NBT03_gp095;Dbxref=GeneID:72551511;Name=OPG116;gbkey=Gene;gene=OPG116;gene_biotype=protein_coding;locus_tag=NBT03_gp095;old_locus_tag=MPXV-M5312_HM12_Rivers-099 +NC_063383.1 RefSeq CDS 95361 96017 . + 0 ID=cds-YP_010377098.1;Parent=gene-NBT03_gp095;Dbxref=GenBank:YP_010377098.1,GeneID:72551511;Name=OPG116;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp101%3B uracil DNA glycosylase%3B DNA polymerase processivity factor%3B similar to VACV-WR E4R and VACV-Cop D4R;gbkey=CDS;gene=OPG116;locus_tag=NBT03_gp095;product=Uracil DNA glycosylase superfamily;protein_id=YP_010377098.1 +NC_063383.1 RefSeq gene 96049 98406 . + . ID=gene-NBT03_gp096;Dbxref=GeneID:72551512;Name=OPG117;gbkey=Gene;gene=OPG117;gene_biotype=protein_coding;locus_tag=NBT03_gp096;old_locus_tag=MPXV-M5312_HM12_Rivers-100 +NC_063383.1 RefSeq CDS 96049 98406 . + 0 ID=cds-YP_010377099.1;Parent=gene-NBT03_gp096;Dbxref=GenBank:YP_010377099.1,GeneID:72551512;Name=OPG117;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp102%3B nucleic acid-independent nucleoside triphosphatase%3B NTPase%2C DNA primase%3B similar to VACV-WR E5R and VACV-Cop D5R;gbkey=CDS;gene=OPG117;locus_tag=NBT03_gp096;product=NTPase (1);protein_id=YP_010377099.1 +NC_063383.1 RefSeq gene 98446 100359 . + . ID=gene-NBT03_gp097;Dbxref=GeneID:72551513;Name=OPG118;gbkey=Gene;gene=OPG118;gene_biotype=protein_coding;locus_tag=NBT03_gp097;old_locus_tag=MPXV-M5312_HM12_Rivers-101 +NC_063383.1 RefSeq CDS 98446 100359 . + 0 ID=cds-YP_010377100.1;Parent=gene-NBT03_gp097;Dbxref=GenBank:YP_010377100.1,GeneID:72551513;Name=OPG118;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp103%3B early transcription factor%2C small subunit%2C VETF-s%3B Morphogenesis%3B similar to VACV-WR E6R and VACV-Cop D6R;gbkey=CDS;gene=OPG118;locus_tag=NBT03_gp097;product=Early transcription factor 70 kDa subunit;protein_id=YP_010377100.1 +NC_063383.1 RefSeq gene 100386 100871 . + . ID=gene-NBT03_gp098;Dbxref=GeneID:72551514;Name=OPG119;gbkey=Gene;gene=OPG119;gene_biotype=protein_coding;locus_tag=NBT03_gp098;old_locus_tag=MPXV-M5312_HM12_Rivers-102 +NC_063383.1 RefSeq CDS 100386 100871 . + 0 ID=cds-YP_010377101.1;Parent=gene-NBT03_gp098;Dbxref=GenBank:YP_010377101.1,GeneID:72551514;Name=OPG119;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp104%3B RNA polymerase%2C 18 kDa subunit (RPO18)%3B similar to VACV-WR E7R and VACV-Cop D7R;gbkey=CDS;gene=OPG119;locus_tag=NBT03_gp098;product=RNA polymerase subunit RPO18;protein_id=YP_010377101.1 +NC_063383.1 RefSeq gene 100834 101748 . - . ID=gene-NBT03_gp099;Dbxref=GeneID:72551515;Name=OPG120;gbkey=Gene;gene=OPG120;gene_biotype=protein_coding;locus_tag=NBT03_gp099;old_locus_tag=MPXV-M5312_HM12_Rivers-103 +NC_063383.1 RefSeq CDS 100834 101748 . - 0 ID=cds-YP_010377102.1;Parent=gene-NBT03_gp099;Dbxref=GenBank:YP_010377102.1,GeneID:72551515;Name=OPG120;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp105%3B IMV surface membrane 32 kDa protein%3B binding to cell surface chondroitin sulfate%3B IMV adsorption to cell surface%3B GAG-binding IMV membrane protein%3B similar to VACV-WR E8L and VACV-Cop D8L;gbkey=CDS;gene=OPG120;locus_tag=NBT03_gp099;product=Carbonic anhydrase;protein_id=YP_010377102.1 +NC_063383.1 RefSeq gene 101790 102431 . + . ID=gene-NBT03_gp100;Dbxref=GeneID:72551516;Name=OPG121;gbkey=Gene;gene=OPG121;gene_biotype=protein_coding;locus_tag=NBT03_gp100;old_locus_tag=MPXV-M5312_HM12_Rivers-104 +NC_063383.1 RefSeq CDS 101790 102431 . + 0 ID=cds-YP_010377103.1;Parent=gene-NBT03_gp100;Dbxref=GenBank:YP_010377103.1,GeneID:72551516;Name=OPG121;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp106%3B Mut-like%3B mRNA decapping enzyme%3B similar to VACV-WR E9R and VACV-Cop D9R;gbkey=CDS;gene=OPG121;locus_tag=NBT03_gp100;product=NUDIX domain protein;protein_id=YP_010377103.1 +NC_063383.1 RefSeq gene 102428 103174 . + . ID=gene-NBT03_gp101;Dbxref=GeneID:72551517;Name=OPG122;gbkey=Gene;gene=OPG122;gene_biotype=protein_coding;locus_tag=NBT03_gp101;old_locus_tag=MPXV-M5312_HM12_Rivers-105 +NC_063383.1 RefSeq CDS 102428 103174 . + 0 ID=cds-YP_010377104.1;Parent=gene-NBT03_gp101;Dbxref=GenBank:YP_010377104.1,GeneID:72551517;Name=OPG122;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp107%3B down regulation of gene expression%3B Mut-like%3B mRNA decapping enzyme%3B similar to VACV-WR E10R and VACV-Cop D10R;gbkey=CDS;gene=OPG122;locus_tag=NBT03_gp101;product=MutT motif protein;protein_id=YP_010377104.1 +NC_063383.1 RefSeq gene 103175 105070 . - . ID=gene-NBT03_gp102;Dbxref=GeneID:72551518;Name=OPG123;gbkey=Gene;gene=OPG123;gene_biotype=protein_coding;locus_tag=NBT03_gp102;old_locus_tag=MPXV-M5312_HM12_Rivers-106 +NC_063383.1 RefSeq CDS 103175 105070 . - 0 ID=cds-YP_010377105.1;Parent=gene-NBT03_gp102;Dbxref=GenBank:YP_010377105.1,GeneID:72551518;Name=OPG123;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp108%3B nucleoside triphosphate phosphohydrolase I%2C NPH I%3B DNA-dependent ATPase%3B early gene transcription termination factor%3B similar to VACV-WR E11L and VACV-Cop D11L;gbkey=CDS;gene=OPG123;locus_tag=NBT03_gp102;product=Nucleoside triphosphatase I;protein_id=YP_010377105.1 +NC_063383.1 RefSeq gene 105105 105968 . - . ID=gene-NBT03_gp103;Dbxref=GeneID:72551519;Name=OPG124;gbkey=Gene;gene=OPG124;gene_biotype=protein_coding;locus_tag=NBT03_gp103;old_locus_tag=MPXV-M5312_HM12_Rivers-107 +NC_063383.1 RefSeq CDS 105105 105968 . - 0 ID=cds-YP_010377106.1;Parent=gene-NBT03_gp103;Dbxref=GenBank:YP_010377106.1,GeneID:72551519;Name=OPG124;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp109%3B mRNA capping enzyme small subunit%3B mRNA (guanine-N7-)-methyl-transferase%3B transcription initiation factor%3B similar to VACV-WR E12L and VACV-Cop D12L;gbkey=CDS;gene=OPG124;locus_tag=NBT03_gp103;product=mRNA capping enzyme small subunit;protein_id=YP_010377106.1 +NC_063383.1 RefSeq gene 105999 107654 . - . ID=gene-NBT03_gp104;Dbxref=GeneID:72551520;Name=OPG125;gbkey=Gene;gene=OPG125;gene_biotype=protein_coding;locus_tag=NBT03_gp104;old_locus_tag=MPXV-M5312_HM12_Rivers-108 +NC_063383.1 RefSeq CDS 105999 107654 . - 0 ID=cds-YP_010377107.1;Parent=gene-NBT03_gp104;Dbxref=GenBank:YP_010377107.1,GeneID:72551520;Name=OPG125;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp110%3B protein needed for the formation of immature IMV surface membrane%3B Trimeric virion coat protein (rifampicin res)%3B similar to VACV-WR E13L and VACV-Cop D13L;gbkey=CDS;gene=OPG125;locus_tag=NBT03_gp104;product=Rifampicin resistance protein;protein_id=YP_010377107.1 +NC_063383.1 RefSeq gene 107678 108130 . - . ID=gene-NBT03_gp105;Dbxref=GeneID:72551521;Name=OPG126;gbkey=Gene;gene=OPG126;gene_biotype=protein_coding;locus_tag=NBT03_gp105;old_locus_tag=MPXV-M5312_HM12_Rivers-109 +NC_063383.1 RefSeq CDS 107678 108130 . - 0 ID=cds-YP_010377108.1;Parent=gene-NBT03_gp105;Dbxref=GenBank:YP_010377108.1,GeneID:72551521;Name=OPG126;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp111%3B late gene transcription factor%2C VLTF-2%3B similar to VACV-WR A1L and VACV-Cop A1L;gbkey=CDS;gene=OPG126;locus_tag=NBT03_gp105;product=Late transcription factor VLTF-2 (2);protein_id=YP_010377108.1 +NC_063383.1 RefSeq gene 108151 108825 . - . ID=gene-NBT03_gp106;Dbxref=GeneID:72551522;Name=OPG127;gbkey=Gene;gene=OPG127;gene_biotype=protein_coding;locus_tag=NBT03_gp106;old_locus_tag=MPXV-M5312_HM12_Rivers-110 +NC_063383.1 RefSeq CDS 108151 108825 . - 0 ID=cds-YP_010377109.1;Parent=gene-NBT03_gp106;Dbxref=GenBank:YP_010377109.1,GeneID:72551522;Name=OPG127;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp112%3B late gene transcription factor%2C VLTF-3%3B zinc binding%3B similar to VACV-WR A2L and VACV-Cop A2L;gbkey=CDS;gene=OPG127;locus_tag=NBT03_gp106;product=Late transcription factor VLTF-3 (1);protein_id=YP_010377109.1 +NC_063383.1 RefSeq gene 108822 109055 . - . ID=gene-NBT03_gp107;Dbxref=GeneID:72551523;Name=OPG128;gbkey=Gene;gene=OPG128;gene_biotype=protein_coding;locus_tag=NBT03_gp107;old_locus_tag=MPXV-M5312_HM12_Rivers-111 +NC_063383.1 RefSeq CDS 108822 109055 . - 0 ID=cds-YP_010377110.1;Parent=gene-NBT03_gp107;Dbxref=GenBank:YP_010377110.1,GeneID:72551523;Name=OPG128;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp113%3B S-S bond formation pathway protein%3B similar to VACV-WR A3L and VACV-Cop A2.5L;gbkey=CDS;gene=OPG128;locus_tag=NBT03_gp107;product=S-S bond formation pathway protein;protein_id=YP_010377110.1 +NC_063383.1 RefSeq gene 109070 111004 . - . ID=gene-NBT03_gp108;Dbxref=GeneID:72551524;Name=OPG129;gbkey=Gene;gene=OPG129;gene_biotype=protein_coding;locus_tag=NBT03_gp108;old_locus_tag=MPXV-M5312_HM12_Rivers-112 +NC_063383.1 RefSeq CDS 109070 111004 . - 0 ID=cds-YP_010377111.1;Parent=gene-NBT03_gp108;Dbxref=GenBank:YP_010377111.1,GeneID:72551524;Name=OPG129;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp114%3B major virion core protein p4b%3B P4b precursor%3B similar to VACV-WR A4L and VACV-Cop A3L;gbkey=CDS;gene=OPG129;locus_tag=NBT03_gp108;product=Virion core protein P4b;protein_id=YP_010377111.1 +NC_063383.1 RefSeq gene 111057 111902 . - . ID=gene-NBT03_gp109;Dbxref=GeneID:72551525;Name=OPG130;gbkey=Gene;gene=OPG130;gene_biotype=protein_coding;locus_tag=NBT03_gp109;old_locus_tag=MPXV-M5312_HM12_Rivers-113 +NC_063383.1 RefSeq CDS 111057 111902 . - 0 ID=cds-YP_010377112.1;Parent=gene-NBT03_gp109;Dbxref=GenBank:YP_010377112.1,GeneID:72551525;Name=OPG130;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp115%3B 39 kDa immunodominant virion core protein needed for the progression of IV to infectious IMV%3B 39kDa virion core protein%3B similar to VACV-WR A5L and VACV-Cop A4L;gbkey=CDS;gene=OPG130;locus_tag=NBT03_gp109;product=A5L protein-like;protein_id=YP_010377112.1 +NC_063383.1 RefSeq gene 111940 112425 . + . ID=gene-NBT03_gp110;Dbxref=GeneID:72551526;Name=OPG131;gbkey=Gene;gene=OPG131;gene_biotype=protein_coding;locus_tag=NBT03_gp110;old_locus_tag=MPXV-M5312_HM12_Rivers-114 +NC_063383.1 RefSeq CDS 111940 112425 . + 0 ID=cds-YP_010377113.1;Parent=gene-NBT03_gp110;Dbxref=GenBank:YP_010377113.1,GeneID:72551526;Name=OPG131;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp116%3B precursor of RNA polymerase 22 kDa and 21 kDa%3B RNA polymerase subunit (RPO19)%3B similar to VACV-WR A6R and VACV-Cop A5R;gbkey=CDS;gene=OPG131;locus_tag=NBT03_gp110;product=DNA-directed RNA polymerase 19 kDa subunit;protein_id=YP_010377113.1 +NC_063383.1 RefSeq gene 112422 113540 . - . ID=gene-NBT03_gp111;Dbxref=GeneID:72551527;Name=OPG132;gbkey=Gene;gene=OPG132;gene_biotype=protein_coding;locus_tag=NBT03_gp111;old_locus_tag=MPXV-M5312_HM12_Rivers-115 +NC_063383.1 RefSeq CDS 112422 113540 . - 0 ID=cds-YP_010377114.1;Parent=gene-NBT03_gp111;Dbxref=GenBank:YP_010377114.1,GeneID:72551527;Name=OPG132;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp117%3B Viral membrane assembly proteins (VMAP)%2C core protein%3B similar to VACV-WR A7L and VACV-Cop A6L;gbkey=CDS;gene=OPG132;locus_tag=NBT03_gp111;product=Virion morphogenesis protein;protein_id=YP_010377114.1 +NC_063383.1 RefSeq gene 113564 115696 . - . ID=gene-NBT03_gp112;Dbxref=GeneID:72551528;Name=OPG133;gbkey=Gene;gene=OPG133;gene_biotype=protein_coding;locus_tag=NBT03_gp112;old_locus_tag=MPXV-M5312_HM12_Rivers-116 +NC_063383.1 RefSeq CDS 113564 115696 . - 0 ID=cds-YP_010377115.1;Parent=gene-NBT03_gp112;Dbxref=GenBank:YP_010377115.1,GeneID:72551528;Name=OPG133;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp118%3B early transcription factor%2C large subunit%2C VETF-L%3B needed for morphogenesis of the virion core%3B similar to VACV-WR A8L and VACV-Cop A7L;gbkey=CDS;gene=OPG133;locus_tag=NBT03_gp112;product=Early transcription factor 82 kDa subunit;protein_id=YP_010377115.1 +NC_063383.1 RefSeq gene 115750 116628 . + . ID=gene-NBT03_gp113;Dbxref=GeneID:72551529;Name=OPG134;gbkey=Gene;gene=OPG134;gene_biotype=protein_coding;locus_tag=NBT03_gp113;old_locus_tag=MPXV-M5312_HM12_Rivers-117 +NC_063383.1 RefSeq CDS 115750 116628 . + 0 ID=cds-YP_010377116.1;Parent=gene-NBT03_gp113;Dbxref=GenBank:YP_010377116.1,GeneID:72551529;Name=OPG134;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp119%3B intermediate transcription factor%2C VITF-3 34kda subunit%2C 34 kDa%3B similar to VACV-WR A9R and VACV-Cop A8R;gbkey=CDS;gene=OPG134;locus_tag=NBT03_gp113;product=Intermediate transcription factor VITF-3 (1);protein_id=YP_010377116.1 +NC_063383.1 RefSeq gene 116609 116911 . - . ID=gene-NBT03_gp114;Dbxref=GeneID:72551530;Name=OPG135;gbkey=Gene;gene=OPG135;gene_biotype=protein_coding;locus_tag=NBT03_gp114;old_locus_tag=MPXV-M5312_HM12_Rivers-118 +NC_063383.1 RefSeq CDS 116609 116911 . - 0 ID=cds-YP_010377117.1;Parent=gene-NBT03_gp114;Dbxref=GenBank:YP_010377117.1,GeneID:72551530;Name=OPG135;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp120%3B Viral membrane associated%2C early morphogenesis protein%3B similar to VACV-WR A10L and VACV-Cop A9L;gbkey=CDS;gene=OPG135;locus_tag=NBT03_gp114;product=IMV membrane protein A9;protein_id=YP_010377117.1 +NC_063383.1 RefSeq gene 116912 119587 . - . ID=gene-NBT03_gp115;Dbxref=GeneID:72551531;Name=OPG136;gbkey=Gene;gene=OPG136;gene_biotype=protein_coding;locus_tag=NBT03_gp115;old_locus_tag=MPXV-M5312_HM12_Rivers-119 +NC_063383.1 RefSeq CDS 116912 119587 . - 0 ID=cds-YP_010377118.1;Parent=gene-NBT03_gp115;Dbxref=GenBank:YP_010377118.1,GeneID:72551531;Name=OPG136;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp121%3B major virion core protein p4a%3B P4a precursor%3B similar to VACV-WR A11L and VACV-Cop A10L;gbkey=CDS;gene=OPG136;locus_tag=NBT03_gp115;product=Virion core protein P4a;protein_id=YP_010377118.1 +NC_063383.1 RefSeq gene 119602 120558 . + . ID=gene-NBT03_gp116;Dbxref=GeneID:72551532;Name=OPG137;gbkey=Gene;gene=OPG137;gene_biotype=protein_coding;locus_tag=NBT03_gp116;old_locus_tag=MPXV-M5312_HM12_Rivers-120 +NC_063383.1 RefSeq CDS 119602 120558 . + 0 ID=cds-YP_010377119.1;Parent=gene-NBT03_gp116;Dbxref=GenBank:YP_010377119.1,GeneID:72551532;Name=OPG137;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp122%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR A12R and VACV-Cop A11R;gbkey=CDS;gene=OPG137;locus_tag=NBT03_gp116;product=Viral membrane formation protein;protein_id=YP_010377119.1 +NC_063383.1 RefSeq gene 120560 121132 . - . ID=gene-NBT03_gp117;Dbxref=GeneID:72551533;Name=OPG138;gbkey=Gene;gene=OPG138;gene_biotype=protein_coding;locus_tag=NBT03_gp117;old_locus_tag=MPXV-M5312_HM12_Rivers-121 +NC_063383.1 RefSeq CDS 120560 121132 . - 0 ID=cds-YP_010377120.1;Parent=gene-NBT03_gp117;Dbxref=GenBank:YP_010377120.1,GeneID:72551533;Name=OPG138;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp123%3B Virion core and cleavage processing protein%3B similar to VACV-WR A13L and VACV-Cop A12L;gbkey=CDS;gene=OPG138;locus_tag=NBT03_gp117;product=A12 protein;protein_id=YP_010377120.1 +NC_063383.1 RefSeq gene 121156 121368 . - . ID=gene-NBT03_gp118;Dbxref=GeneID:72551534;Name=OPG139;gbkey=Gene;gene=OPG139;gene_biotype=protein_coding;locus_tag=NBT03_gp118;old_locus_tag=MPXV-M5312_HM12_Rivers-122 +NC_063383.1 RefSeq CDS 121156 121368 . - 0 ID=cds-YP_010377121.1;Parent=gene-NBT03_gp118;Dbxref=GenBank:YP_010377121.1,GeneID:72551534;Name=OPG139;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp124%3B IMV inner and outer membrane protein%3B virion maturation%3B similar to VACV-WR A14L and VACV-Cop A13L;gbkey=CDS;gene=OPG139;locus_tag=NBT03_gp118;product=IMV membrane protein A13L;protein_id=YP_010377121.1 +NC_063383.1 RefSeq gene 121474 121746 . - . ID=gene-NBT03_gp119;Dbxref=GeneID:72551535;Name=OPG140;gbkey=Gene;gene=OPG140;gene_biotype=protein_coding;locus_tag=NBT03_gp119;old_locus_tag=MPXV-M5312_HM12_Rivers-123 +NC_063383.1 RefSeq CDS 121474 121746 . - 0 ID=cds-YP_010377122.1;Parent=gene-NBT03_gp119;Dbxref=GenBank:YP_010377122.1,GeneID:72551535;Name=OPG140;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp125%3B IMV inner membrane protein%3B Essential IMV membrane protein%3B similar to VACV-WR A15L and VACV-Cop A14L;gbkey=CDS;gene=OPG140;locus_tag=NBT03_gp119;product=IMV membrane protein A14;protein_id=YP_010377122.1 +NC_063383.1 RefSeq gene 121763 121924 . - . ID=gene-NBT03_gp120;Dbxref=GeneID:72551536;Name=OPG141;gbkey=Gene;gene=OPG141;gene_biotype=protein_coding;locus_tag=NBT03_gp120;old_locus_tag=MPXV-M5312_HM12_Rivers-124 +NC_063383.1 RefSeq CDS 121763 121924 . - 0 ID=cds-YP_010377123.1;Parent=gene-NBT03_gp120;Dbxref=GenBank:YP_010377123.1,GeneID:72551536;Name=OPG141;Note=Taxonomic breadth: chordopoxvirinae%3B Non-essential IMV membrane protein%3B similar to VACV-WR A15.5L and VACV-Cop A14.5L;gbkey=CDS;gene=OPG141;locus_tag=NBT03_gp120;product=DUF1029 domain protein;protein_id=YP_010377123.1 +NC_063383.1 RefSeq gene 121914 122198 . - . ID=gene-NBT03_gp121;Dbxref=GeneID:72551537;Name=OPG142;gbkey=Gene;gene=OPG142;gene_biotype=protein_coding;locus_tag=NBT03_gp121;old_locus_tag=MPXV-M5312_HM12_Rivers-125 +NC_063383.1 RefSeq CDS 121914 122198 . - 0 ID=cds-YP_010377124.1;Parent=gene-NBT03_gp121;Dbxref=GenBank:YP_010377124.1,GeneID:72551537;Name=OPG142;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp126%3B Core protein%3B similar to VACV-WR A16L and VACV-Cop A15L;gbkey=CDS;gene=OPG142;locus_tag=NBT03_gp121;product=Core protein A15;protein_id=YP_010377124.1 +NC_063383.1 RefSeq gene 122182 123315 . - . ID=gene-NBT03_gp122;Dbxref=GeneID:72551538;Name=OPG143;gbkey=Gene;gene=OPG143;gene_biotype=protein_coding;locus_tag=NBT03_gp122;old_locus_tag=MPXV-M5312_HM12_Rivers-126 +NC_063383.1 RefSeq CDS 122182 123315 . - 0 ID=cds-YP_010377125.1;Parent=gene-NBT03_gp122;Dbxref=GenBank:YP_010377125.1,GeneID:72551538;Name=OPG143;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp127%3B soluble myristylated protein%3B essential for entry/fusion%3B similar to VACV-WR A17L and VACV-Cop A16L;gbkey=CDS;gene=OPG143;locus_tag=NBT03_gp122;product=Myristylated protein;protein_id=YP_010377125.1 +NC_063383.1 RefSeq gene 123318 123932 . - . ID=gene-NBT03_gp123;Dbxref=GeneID:72551539;Name=OPG144;gbkey=Gene;gene=OPG144;gene_biotype=protein_coding;locus_tag=NBT03_gp123;old_locus_tag=MPXV-M5312_HM12_Rivers-127 +NC_063383.1 RefSeq CDS 123318 123932 . - 0 ID=cds-YP_010377126.1;Parent=gene-NBT03_gp123;Dbxref=GenBank:YP_010377126.1,GeneID:72551539;Name=OPG144;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp128%3B IMV surface membrane protein%3B early function in virion morphgenesis%3B similar to VACV-WR A18L and VACV-Cop A17L;gbkey=CDS;gene=OPG144;locus_tag=NBT03_gp123;product=IMV membrane protein P21;protein_id=YP_010377126.1 +NC_063383.1 RefSeq gene 123947 125425 . + . ID=gene-NBT03_gp124;Dbxref=GeneID:72551540;Name=OPG145;gbkey=Gene;gene=OPG145;gene_biotype=protein_coding;locus_tag=NBT03_gp124;old_locus_tag=MPXV-M5312_HM12_Rivers-128 +NC_063383.1 RefSeq CDS 123947 125425 . + 0 ID=cds-YP_010377127.1;Parent=gene-NBT03_gp124;Dbxref=GenBank:YP_010377127.1,GeneID:72551540;Name=OPG145;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp129%3B virion core associated DNA helicase%3B post-replicative negative transcription elongation factor%3B transcript release factor%3B similar to VACV-WR A19R and VACV-Cop A18R;gbkey=CDS;gene=OPG145;locus_tag=NBT03_gp124;product=DNA helicase;protein_id=YP_010377127.1 +NC_063383.1 RefSeq gene 125406 125639 . - . ID=gene-NBT03_gp125;Dbxref=GeneID:72551541;Name=OPG146;gbkey=Gene;gene=OPG146;gene_biotype=protein_coding;locus_tag=NBT03_gp125;old_locus_tag=MPXV-M5312_HM12_Rivers-129 +NC_063383.1 RefSeq CDS 125406 125639 . - 0 ID=cds-YP_010377128.1;Parent=gene-NBT03_gp125;Dbxref=GenBank:YP_010377128.1,GeneID:72551541;Name=OPG146;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp130%3B Zinc finger-like protein%3B similar to VACV-WR A20L and VACV-Cop A19L;gbkey=CDS;gene=OPG146;locus_tag=NBT03_gp125;product=Zinc finger-like protein (1);protein_id=YP_010377128.1 +NC_063383.1 RefSeq gene 125640 125987 . - . ID=gene-NBT03_gp126;Dbxref=GeneID:72551542;Name=OPG147;gbkey=Gene;gene=OPG147;gene_biotype=protein_coding;locus_tag=NBT03_gp126;old_locus_tag=MPXV-M5312_HM12_Rivers-130 +NC_063383.1 RefSeq CDS 125640 125987 . - 0 ID=cds-YP_010377129.1;Parent=gene-NBT03_gp126;Dbxref=GenBank:YP_010377129.1,GeneID:72551542;Name=OPG147;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp131%3B IMV membrane protein%2C entry/fusion complex component%3B similar to VACV-WR A21L and VACV-Cop A21L;gbkey=CDS;gene=OPG147;locus_tag=NBT03_gp126;product=IMV membrane protein A21;protein_id=YP_010377129.1 +NC_063383.1 RefSeq gene 125986 127266 . + . ID=gene-NBT03_gp127;Dbxref=GeneID:72551543;Name=OPG148;gbkey=Gene;gene=OPG148;gene_biotype=protein_coding;locus_tag=NBT03_gp127;old_locus_tag=MPXV-M5312_HM12_Rivers-131 +NC_063383.1 RefSeq CDS 125986 127266 . + 0 ID=cds-YP_010377130.1;Parent=gene-NBT03_gp127;Dbxref=GenBank:YP_010377130.1,GeneID:72551543;Name=OPG148;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp132%3B processivity factor for the viral DNA polymerase%2C VPF%3B similar to VACV-WR A22R and VACV-Cop A20R;gbkey=CDS;gene=OPG148;locus_tag=NBT03_gp127;product=DNA polymerase processivity factor;protein_id=YP_010377130.1 +NC_063383.1 RefSeq gene 127196 127759 . + . ID=gene-NBT03_gp128;Dbxref=GeneID:72551544;Name=OPG149;gbkey=Gene;gene=OPG149;gene_biotype=protein_coding;locus_tag=NBT03_gp128;old_locus_tag=MPXV-M5312_HM12_Rivers-132 +NC_063383.1 RefSeq CDS 127196 127759 . + 0 ID=cds-YP_010377131.1;Parent=gene-NBT03_gp128;Dbxref=GenBank:YP_010377131.1,GeneID:72551544;Name=OPG149;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp133%3B Holliday junction resolvase%3B similar to VACV-WR A23R and VACV-Cop A22R;gbkey=CDS;gene=OPG149;locus_tag=NBT03_gp128;product=Holliday junction resolvase;protein_id=YP_010377131.1 +NC_063383.1 RefSeq gene 127779 128927 . + . ID=gene-NBT03_gp129;Dbxref=GeneID:72551545;Name=OPG150;gbkey=Gene;gene=OPG150;gene_biotype=protein_coding;locus_tag=NBT03_gp129;old_locus_tag=MPXV-M5312_HM12_Rivers-133 +NC_063383.1 RefSeq CDS 127779 128927 . + 0 ID=cds-YP_010377132.1;Parent=gene-NBT03_gp129;Dbxref=GenBank:YP_010377132.1,GeneID:72551545;Name=OPG150;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp134%3B intermediate transcription factor%2C VITF-3%2C 45 kDa subunit%3B similar to VACV-WR A24R and VACV-Cop A23R;gbkey=CDS;gene=OPG150;locus_tag=NBT03_gp129;product=Intermediate transcription factor VITF-3 (2);protein_id=YP_010377132.1 +NC_063383.1 RefSeq gene 128924 132418 . + . ID=gene-NBT03_gp130;Dbxref=GeneID:72551546;Name=OPG151;gbkey=Gene;gene=OPG151;gene_biotype=protein_coding;locus_tag=NBT03_gp130;old_locus_tag=MPXV-M5312_HM12_Rivers-134 +NC_063383.1 RefSeq CDS 128924 132418 . + 0 ID=cds-YP_010377133.1;Parent=gene-NBT03_gp130;Dbxref=GenBank:YP_010377133.1,GeneID:72551546;Name=OPG151;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp135%3B RNA polymerase%2C 132 kDa subunit (RPO132)%3B similar to VACV-WR A25R and VACV-Cop A24R;gbkey=CDS;gene=OPG151;locus_tag=NBT03_gp130;product=DNA-dependent RNA polymerase subunit rpo132;protein_id=YP_010377133.1 +NC_063383.1 RefSeq sequence_feature 132396 136092 . - . ID=id-NC_063383.1:132396..136092;exon_number=OPG152;gbkey=misc_feature;number=OPG152 +NC_063383.1 RefSeq gene 136138 137667 . - . ID=gene-NBT03_gp131;Dbxref=GeneID:72551547;Name=OPG153;gbkey=Gene;gene=OPG153;gene_biotype=protein_coding;locus_tag=NBT03_gp131;old_locus_tag=MPXV-M5312_HM12_Rivers-137 +NC_063383.1 RefSeq CDS 136138 137667 . - 0 ID=cds-YP_010377134.1;Parent=gene-NBT03_gp131;Dbxref=GenBank:YP_010377134.1,GeneID:72551547;Name=OPG153;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp138%3B major component of IMV surface tubules%3B A-type inclusion protein%3B P4c precursor%3B similar to VACV-WR A28L and VACV-Cop A26L;gbkey=CDS;gene=OPG153;locus_tag=NBT03_gp131;product=Orthopoxvirus A26L/A30L protein;protein_id=YP_010377134.1 +NC_063383.1 RefSeq gene 137718 138050 . - . ID=gene-NBT03_gp132;Dbxref=GeneID:72551548;Name=OPG154;gbkey=Gene;gene=OPG154;gene_biotype=protein_coding;locus_tag=NBT03_gp132;old_locus_tag=MPXV-M5312_HM12_Rivers-138 +NC_063383.1 RefSeq CDS 137718 138050 . - 0 ID=cds-YP_010377135.1;Parent=gene-NBT03_gp132;Dbxref=GenBank:YP_010377135.1,GeneID:72551548;Name=OPG154;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp139%3B IMV surface membrane 14 kDa fusion protein%3B binding to cell surface heparan%3B similar to VACV-WR A29L and VACV-Cop A27L;gbkey=CDS;gene=OPG154;locus_tag=NBT03_gp132;product=IMV surface fusion protein;protein_id=YP_010377135.1 +NC_063383.1 RefSeq gene 138051 138491 . - . ID=gene-NBT03_gp133;Dbxref=GeneID:72551549;Name=OPG155;gbkey=Gene;gene=OPG155;gene_biotype=protein_coding;locus_tag=NBT03_gp133;old_locus_tag=MPXV-M5312_HM12_Rivers-139 +NC_063383.1 RefSeq CDS 138051 138491 . - 0 ID=cds-YP_010377136.1;Parent=gene-NBT03_gp133;Dbxref=GenBank:YP_010377136.1,GeneID:72551549;Name=OPG155;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp140%3B IMV MP/Virus entry%3B similar to VACV-WR A30L and VACV-Cop A28L;gbkey=CDS;gene=OPG155;locus_tag=NBT03_gp133;product=Envelope protein A28 homolog;protein_id=YP_010377136.1 +NC_063383.1 RefSeq gene 138492 139409 . - . ID=gene-NBT03_gp134;Dbxref=GeneID:72551550;Name=OPG156;gbkey=Gene;gene=OPG156;gene_biotype=protein_coding;locus_tag=NBT03_gp134;old_locus_tag=MPXV-M5312_HM12_Rivers-140 +NC_063383.1 RefSeq CDS 138492 139409 . - 0 ID=cds-YP_010377137.1;Parent=gene-NBT03_gp134;Dbxref=GenBank:YP_010377137.1,GeneID:72551550;Name=OPG156;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp141%3B RNA polymerase%2C 35 kDa subunit (RPO35)%3B similar to VACV-WR A31L and VACV-Cop A29L;gbkey=CDS;gene=OPG156;locus_tag=NBT03_gp134;product=DNA-directed RNA polymerase 35 kDa subunit;protein_id=YP_010377137.1 +NC_063383.1 RefSeq gene 139372 139608 . - . ID=gene-NBT03_gp135;Dbxref=GeneID:72551551;Name=OPG157;gbkey=Gene;gene=OPG157;gene_biotype=protein_coding;locus_tag=NBT03_gp135;old_locus_tag=MPXV-M5312_HM12_Rivers-141 +NC_063383.1 RefSeq CDS 139372 139608 . - 0 ID=cds-YP_010377138.1;Parent=gene-NBT03_gp135;Dbxref=GenBank:YP_010377138.1,GeneID:72551551;Name=OPG157;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp142%3B IMV protein%3B similar to VACV-WR A32L and VACV-Cop A30L;gbkey=CDS;gene=OPG157;locus_tag=NBT03_gp135;product=IMV membrane protein A30;protein_id=YP_010377138.1 +NC_063383.1 RefSeq gene 139641 139769 . - . ID=gene-NBT03_gp136;Dbxref=GeneID:72551552;Name=OPG158;gbkey=Gene;gene=OPG158;gene_biotype=protein_coding;locus_tag=NBT03_gp136;old_locus_tag=MPXV-M5312_HM12_Rivers-142 +NC_063383.1 RefSeq CDS 139641 139769 . - 0 ID=cds-YP_010377139.1;Parent=gene-NBT03_gp136;Dbxref=GenBank:YP_010377139.1,GeneID:72551552;Name=OPG158;Note=Viral membrane assembly proteins (VMAP)%3B similar to VACV-Cop A30.5L;gbkey=CDS;gene=OPG158;locus_tag=NBT03_gp136;product=A32.5L;protein_id=YP_010377139.1 +NC_063383.1 RefSeq gene 139768 140205 . + . ID=gene-NBT03_gp137;Dbxref=GeneID:72551553;Name=OPG159;gbkey=Gene;gene=OPG159;gene_biotype=protein_coding;locus_tag=NBT03_gp137;old_locus_tag=MPXV-M5312_HM12_Rivers-143 +NC_063383.1 RefSeq CDS 139768 140205 . + 0 ID=cds-YP_010377140.1;Parent=gene-NBT03_gp137;Dbxref=GenBank:YP_010377140.1,GeneID:72551553;Name=OPG159;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp143%3B Hypothetical protein%3B similar to VACV-WR A33R and VACV-Cop A31R;gbkey=CDS;gene=OPG159;locus_tag=NBT03_gp137;product=CPXV166 protein;protein_id=YP_010377140.1 +NC_063383.1 RefSeq gene 140172 141074 . - . ID=gene-NBT03_gp138;Dbxref=GeneID:72551554;Name=OPG160;gbkey=Gene;gene=OPG160;gene_biotype=protein_coding;locus_tag=NBT03_gp138;old_locus_tag=MPXV-M5312_HM12_Rivers-144 +NC_063383.1 RefSeq CDS 140172 141074 . - 0 ID=cds-YP_010377141.1;Parent=gene-NBT03_gp138;Dbxref=GenBank:YP_010377141.1,GeneID:72551554;Name=OPG160;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp144%3B DNA packaging into virion%3B NTP-binding motif A%3B ATPase/DNA packaging protein%3B similar to VACV-WR A34L and VACV-Cop A32L;gbkey=CDS;gene=OPG160;locus_tag=NBT03_gp138;product=ATPase A32;protein_id=YP_010377141.1 +NC_063383.1 RefSeq gene 141102 141647 . + . ID=gene-NBT03_gp139;Dbxref=GeneID:72551555;Name=OPG161;gbkey=Gene;gene=OPG161;gene_biotype=protein_coding;locus_tag=NBT03_gp139;old_locus_tag=MPXV-M5312_HM12_Rivers-145 +NC_063383.1 RefSeq CDS 141102 141647 . + 0 ID=cds-YP_010377142.1;Parent=gene-NBT03_gp139;Dbxref=GenBank:YP_010377142.1,GeneID:72551555;Name=OPG161;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp145%3B EEV envelope glycoprotein%2C needed for formation of actin-containing microvilli and cell-to-cell spread of virion%3B interacts with VAC A36R%3B EEV membrane phosphoglycoprotein%2C C-type lectin-like domain%3B similar to VACV-WR A35R and VACV-Cop A33R;gbkey=CDS;gene=OPG161;locus_tag=NBT03_gp139;product=EEV glycoprotein (1);protein_id=YP_010377142.1 +NC_063383.1 RefSeq gene 141652 142158 . + . ID=gene-NBT03_gp140;Dbxref=GeneID:72551556;Name=OPG162;gbkey=Gene;gene=OPG162;gene_biotype=protein_coding;locus_tag=NBT03_gp140;old_locus_tag=MPXV-M5312_HM12_Rivers-146 +NC_063383.1 RefSeq CDS 141652 142158 . + 0 ID=cds-YP_010377143.1;Parent=gene-NBT03_gp140;Dbxref=GenBank:YP_010377143.1,GeneID:72551556;Name=OPG162;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp146%3B EEV envelope glycoprotein%2C lectin-like%3B required for infectivity of EEV%2C formation of actin-containing microvilli%2C and cell-to-cell spread of virion%3B C-type lectin-like IEV/EEV glycoprotein%3B similar to VACV-WR A36R and VACV-Cop A34R;gbkey=CDS;gene=OPG162;locus_tag=NBT03_gp140;product=EEV glycoprotein (2);protein_id=YP_010377143.1 +NC_063383.1 RefSeq gene 142202 142732 . + . ID=gene-NBT03_gp141;Dbxref=GeneID:72551557;Name=OPG163;gbkey=Gene;gene=OPG163;gene_biotype=protein_coding;locus_tag=NBT03_gp141;old_locus_tag=MPXV-M5312_HM12_Rivers-147 +NC_063383.1 RefSeq CDS 142202 142732 . + 0 ID=cds-YP_010377144.1;Parent=gene-NBT03_gp141;Dbxref=GenBank:YP_010377144.1,GeneID:72551557;Name=OPG163;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp147%3B MHC class II antigen presentation inhibitor%3B similar to VACV-WR A37R and VACV-Cop A35R;gbkey=CDS;gene=OPG163;locus_tag=NBT03_gp141;product=MHC class II antigen presentation inhibitor;protein_id=YP_010377144.1 +NC_063383.1 RefSeq gene 142778 143464 . + . ID=gene-NBT03_gp142;Dbxref=GeneID:72551558;Name=OPG164;gbkey=Gene;gene=OPG164;gene_biotype=protein_coding;locus_tag=NBT03_gp142;old_locus_tag=MPXV-M5312_HM12_Rivers-148 +NC_063383.1 RefSeq CDS 142778 143464 . + 0 ID=cds-YP_010377145.1;Parent=gene-NBT03_gp142;Dbxref=GenBank:YP_010377145.1,GeneID:72551558;Name=OPG164;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp148%3B IEV but not CEV envelope protein%3B plays critical role for actin tail formation%3B interacts with VAC A33R and A34R%3B IEV transmembrane phosphoprotein%3B similar to VACV-WR A38R and VACV-Cop A36R;gbkey=CDS;gene=OPG164;locus_tag=NBT03_gp142;product=IEV transmembrane phosphoprotein;protein_id=YP_010377145.1 +NC_063383.1 RefSeq gene 143516 144322 . + . ID=gene-NBT03_gp143;Dbxref=GeneID:72551559;Name=OPG165;gbkey=Gene;gene=OPG165;gene_biotype=protein_coding;locus_tag=NBT03_gp143;old_locus_tag=MPXV-M5312_HM12_Rivers-149 +NC_063383.1 RefSeq CDS 143516 144322 . + 0 ID=cds-YP_010377146.1;Parent=gene-NBT03_gp143;Dbxref=GenBank:YP_010377146.1,GeneID:72551559;Name=OPG165;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp149%3B Hypothetical protein%3B similar to VACV-WR A39R and VACV-Cop A37R;gbkey=CDS;gene=OPG165;locus_tag=NBT03_gp143;product=CPXV173 protein;protein_id=YP_010377146.1 +NC_063383.1 RefSeq gene 144398 144577 . + . ID=gene-NBT03_gp144;Dbxref=GeneID:72551560;Name=OPG166;gbkey=Gene;gene=OPG166;gene_biotype=protein_coding;locus_tag=NBT03_gp144 +NC_063383.1 RefSeq CDS 144398 144577 . + 0 ID=cds-YP_010415322.1;Parent=gene-NBT03_gp144;Dbxref=GenBank:YP_010415322.1,GeneID:72551560;Name=OPG166;Note=Hypothetical protein%3B according to YP_233043.1%2C this VACV-WR protein was purified by sucrose gradient centrifugation%3B similar to VACWR161 and VARGAR-A43R;gbkey=CDS;gene=OPG166;locus_tag=NBT03_gp144;product=hypothetical protein;protein_id=YP_010415322.1 +NC_063383.1 RefSeq gene 144574 145407 . - . ID=gene-NBT03_gp145;Dbxref=GeneID:72551561;Name=OPG167;gbkey=Gene;gene=OPG167;gene_biotype=protein_coding;locus_tag=NBT03_gp145;old_locus_tag=MPXV-M5312_HM12_Rivers-150 +NC_063383.1 RefSeq CDS 144574 145407 . - 0 ID=cds-YP_010377147.1;Parent=gene-NBT03_gp145;Dbxref=GenBank:YP_010377147.1,GeneID:72551561;Name=OPG167;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp150%3B integral membrane glycoprotein%3B immunoglobulin-like%3B regulation of the influx of extracellular Ca2+%3B CD47-like%3B similar to VACV-WR A40L and VACV-Cop A38L;gbkey=CDS;gene=OPG167;locus_tag=NBT03_gp145;product=CD47-like protein;protein_id=YP_010377147.1 +NC_063383.1 RefSeq sequence_feature 145423 145856 . + . ID=id-NC_063383.1:145423..145856;exon_number=OPG168;gbkey=misc_feature;number=OPG168 +NC_063383.1 RefSeq sequence_feature 145857 146039 . + . ID=id-NC_063383.1:145857..146039;exon_number=OPG169;gbkey=misc_feature;number=OPG169 +NC_063383.1 RefSeq gene 146113 146778 . - . ID=gene-NBT03_gp146;Dbxref=GeneID:72551562;Name=OPG170;gbkey=Gene;gene=OPG170;gene_biotype=protein_coding;locus_tag=NBT03_gp146;old_locus_tag=MPXV-M5312_HM12_Rivers-151 +NC_063383.1 RefSeq CDS 146113 146778 . - 0 ID=cds-YP_010377148.1;Parent=gene-NBT03_gp146;Dbxref=GenBank:YP_010377148.1,GeneID:72551562;Name=OPG170;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp151%3B secreted protein reducing infiltration of inflammatory cells into the infected area%3B Chemokine binding protein%3B similar to VACV-WR A41L and VACV-Cop A41L;gbkey=CDS;gene=OPG170;locus_tag=NBT03_gp146;product=Chemokine binding protein;protein_id=YP_010377148.1 +NC_063383.1 RefSeq gene 146988 147389 . + . ID=gene-NBT03_gp147;Dbxref=GeneID:72551563;Name=OPG171;gbkey=Gene;gene=OPG171;gene_biotype=protein_coding;locus_tag=NBT03_gp147;old_locus_tag=MPXV-M5312_HM12_Rivers-152 +NC_063383.1 RefSeq CDS 146988 147389 . + 0 ID=cds-YP_010377149.1;Parent=gene-NBT03_gp147;Dbxref=GenBank:YP_010377149.1,GeneID:72551563;Name=OPG171;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp152%3B Profilin-like protein%2C ATI-localized%3B similar to VACV-WR A42R and VACV-Cop A42R;gbkey=CDS;gene=OPG171;locus_tag=NBT03_gp147;product=Profilin domain protein;protein_id=YP_010377149.1 +NC_063383.1 RefSeq gene 147427 148017 . + . ID=gene-NBT03_gp148;Dbxref=GeneID:72551564;Name=OPG172;gbkey=Gene;gene=OPG172;gene_biotype=protein_coding;locus_tag=NBT03_gp148;old_locus_tag=MPXV-M5312_HM12_Rivers-153 +NC_063383.1 RefSeq CDS 147427 148017 . + 0 ID=cds-YP_010377150.1;Parent=gene-NBT03_gp148;Dbxref=GenBank:YP_010377150.1,GeneID:72551564;Name=OPG172;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp153%3B Type I membrane glycoprotein%3B similar to VACV-WR A43R and VACV-Cop A43R;gbkey=CDS;gene=OPG172;locus_tag=NBT03_gp148;product=Type-I membrane glycoprotein;protein_id=YP_010377150.1 +NC_063383.1 RefSeq gene 148037 148261 . + . ID=gene-NBT03_gp149;Dbxref=GeneID:72551565;Name=OPG173;gbkey=Gene;gene=OPG173;gene_biotype=protein_coding;locus_tag=NBT03_gp149;old_locus_tag=MPXV-M5312_HM12_Rivers-154 +NC_063383.1 RefSeq CDS 148037 148261 . + 0 ID=cds-YP_010377151.1;Parent=gene-NBT03_gp149;Dbxref=GenBank:YP_010377151.1,GeneID:72551565;Name=OPG173;Note=Old product: MPXVgp154%3B Hypothetical protein%3B similar to VACV-WR A44R and VACV-Cop A43.5R;gbkey=CDS;gene=OPG173;locus_tag=NBT03_gp149;product=MPXVgp154;protein_id=YP_010377151.1 +NC_063383.1 RefSeq gene 148355 149395 . - . ID=gene-NBT03_gp150;Dbxref=GeneID:72551566;Name=OPG174;gbkey=Gene;gene=OPG174;gene_biotype=protein_coding;locus_tag=NBT03_gp150;old_locus_tag=MPXV-M5312_HM12_Rivers-155 +NC_063383.1 RefSeq CDS 148355 149395 . - 0 ID=cds-YP_010377152.1;Parent=gene-NBT03_gp150;Dbxref=GenBank:YP_010377152.1,GeneID:72551566;Name=OPG174;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp155%3B 3-b-Hydroxy-delta5-steroid dehydrogenase%3B 3 beta-hydroxysteroid dehydrogenase/delta 5->4 isomerase%3B similar to VACV-WR A45L and VACV-Cop A44L;gbkey=CDS;gene=OPG174;locus_tag=NBT03_gp150;product=Hydroxysteroid dehydrogenase;protein_id=YP_010377152.1 +NC_063383.1 RefSeq gene 149442 149819 . + . ID=gene-NBT03_gp151;Dbxref=GeneID:72551567;Name=OPG175;gbkey=Gene;gene=OPG175;gene_biotype=protein_coding;locus_tag=NBT03_gp151;old_locus_tag=MPXV-M5312_HM12_Rivers-156 +NC_063383.1 RefSeq CDS 149442 149819 . + 0 ID=cds-YP_010377153.1;Parent=gene-NBT03_gp151;Dbxref=GenBank:YP_010377153.1,GeneID:72551567;Name=OPG175;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp156%3B virion core protein%3B Inactive Cu-Zn superoxide dismutase-like virion protein%3B similar to VACV-WR A46R and VACV-Cop A45R;gbkey=CDS;gene=OPG175;locus_tag=NBT03_gp151;product=Copper/zinc superoxide dismutase;protein_id=YP_010377153.1 +NC_063383.1 RefSeq gene 149809 150531 . + . ID=gene-NBT03_gp152;Dbxref=GeneID:72551568;Name=OPG176;gbkey=Gene;gene=OPG176;gene_biotype=protein_coding;locus_tag=NBT03_gp152;old_locus_tag=MPXV-M5312_HM12_Rivers-157 +NC_063383.1 RefSeq CDS 149809 150531 . + 0 ID=cds-YP_010377154.1;Parent=gene-NBT03_gp152;Dbxref=GenBank:YP_010377154.1,GeneID:72551568;Name=OPG176;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp157%3B IL-1/TLR signaling inhibitor%3B similar to VACV-WR A47R and VACV-Cop A46R;gbkey=CDS;gene=OPG176;locus_tag=NBT03_gp152;product=Bcl-2-like protein;protein_id=YP_010377154.1 +NC_063383.1 RefSeq sequence_feature 150684 151407 . - . ID=id-NC_063383.1:150684..151407;exon_number=OPG177;gbkey=misc_feature;number=OPG177 +NC_063383.1 RefSeq gene 151509 152123 . + . ID=gene-NBT03_gp153;Dbxref=GeneID:72551569;Name=OPG178;gbkey=Gene;gene=OPG178;gene_biotype=protein_coding;locus_tag=NBT03_gp153;old_locus_tag=MPXV-M5312_HM12_Rivers-158 +NC_063383.1 RefSeq CDS 151509 152123 . + 0 ID=cds-YP_010377155.1;Parent=gene-NBT03_gp153;Dbxref=GenBank:YP_010377155.1,GeneID:72551569;Name=OPG178;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp159%3B thymidylate kinase%3B start of ORF is missing approx. 37 AA compared to CPXVs%3B similar to VACV-WR A49R and VACV-Cop A48R;gbkey=CDS;gene=OPG178;locus_tag=NBT03_gp153;product=Thymidylate kinase;protein_id=YP_010377155.1 +NC_063383.1 RefSeq sequence_feature 152172 152660 . + . ID=id-NC_063383.1:152172..152660;exon_number=OPG179;gbkey=misc_feature;number=OPG179 +NC_063383.1 RefSeq gene 152692 154371 . + . ID=gene-NBT03_gp154;Dbxref=GeneID:72551570;Name=OPG180;gbkey=Gene;gene=OPG180;gene_biotype=protein_coding;locus_tag=NBT03_gp154;old_locus_tag=MPXV-M5312_HM12_Rivers-159 +NC_063383.1 RefSeq CDS 152692 154371 . + 0 ID=cds-YP_010377156.1;Parent=gene-NBT03_gp154;Dbxref=GenBank:YP_010377156.1,GeneID:72551570;Name=OPG180;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp160%3B ATP-dependent DNA ligase%3B similar to VACV-WR A50R and VACV-Cop A50R;gbkey=CDS;gene=OPG180;locus_tag=NBT03_gp154;product=DNA ligase (2);protein_id=YP_010377156.1 +NC_063383.1 RefSeq gene 154412 155416 . + . ID=gene-NBT03_gp155;Dbxref=GeneID:72551571;Name=OPG181;gbkey=Gene;gene=OPG181;gene_biotype=protein_coding;locus_tag=NBT03_gp155;old_locus_tag=MPXV-M5312_HM12_Rivers-160 +NC_063383.1 RefSeq CDS 154412 155416 . + 0 ID=cds-YP_010377157.1;Parent=gene-NBT03_gp155;Dbxref=GenBank:YP_010377157.1,GeneID:72551571;Name=OPG181;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp161%3B Hypothetical protein%3B similar to VACV-WR A51R and VACV-Cop A51R;gbkey=CDS;gene=OPG181;locus_tag=NBT03_gp155;product=M137R;protein_id=YP_010377157.1 +NC_063383.1 RefSeq sequence_feature 155485 156037 . + . ID=id-NC_063383.1:155485..156037;exon_number=OPG182;gbkey=misc_feature;number=OPG182 +NC_063383.1 RefSeq sequence_feature 156355 156916 . + . ID=id-NC_063383.1:156355..156916;exon_number=OPG183;gbkey=misc_feature;number=OPG183 +NC_063383.1 RefSeq sequence_feature 157176 158867 . + . ID=id-NC_063383.1:157176..158867;exon_number=OPG184;gbkey=misc_feature;number=OPG184 +NC_063383.1 RefSeq gene 158917 159858 . + . ID=gene-NBT03_gp156;Dbxref=GeneID:72551572;Name=OPG185;gbkey=Gene;gene=OPG185;gene_biotype=protein_coding;locus_tag=NBT03_gp156;old_locus_tag=MPXV-M5312_HM12_Rivers-162 +NC_063383.1 RefSeq CDS 158917 159858 . + 0 ID=cds-YP_010377158.1;Parent=gene-NBT03_gp156;Dbxref=GenBank:YP_010377158.1,GeneID:72551572;Name=OPG185;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp163%3B EEV envelope and cell membrane glycoprotein hemagglutinin%3B inhibition of the ability of infected cells to fuse%3B interacts with VAC F13L%3B similar to VACV-WR B2R and VACV-Cop A56R;gbkey=CDS;gene=OPG185;locus_tag=NBT03_gp156;product=Hemagglutinin;protein_id=YP_010377158.1 +NC_063383.1 RefSeq sequence_feature 159876 160470 . + . ID=id-NC_063383.1:159876..160470;exon_number=OPG186;gbkey=misc_feature;number=OPG186 +NC_063383.1 RefSeq gene 160622 161533 . + . ID=gene-NBT03_gp157;Dbxref=GeneID:72551573;Name=OPG187;gbkey=Gene;gene=OPG187;gene_biotype=protein_coding;locus_tag=NBT03_gp157;old_locus_tag=MPXV-M5312_HM12_Rivers-163 +NC_063383.1 RefSeq CDS 160622 161533 . + 0 ID=cds-YP_010377159.1;Parent=gene-NBT03_gp157;Dbxref=GenBank:YP_010377159.1,GeneID:72551573;Name=OPG187;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp164%3B serine%3B Ser/Thr Kinase%3B similar to VACV-WR B3R and VACV-Cop B1R;gbkey=CDS;gene=OPG187;locus_tag=NBT03_gp157;product=Ser/thr kinase;protein_id=YP_010377159.1 +NC_063383.1 RefSeq gene 161596 163107 . + . ID=gene-NBT03_gp158;Dbxref=GeneID:72551574;Name=OPG188;gbkey=Gene;gene=OPG188;gene_biotype=protein_coding;locus_tag=NBT03_gp158;old_locus_tag=MPXV-M5312_HM12_Rivers-164 +NC_063383.1 RefSeq CDS 161596 163107 . + 0 ID=cds-YP_010377160.1;Parent=gene-NBT03_gp158;Dbxref=GenBank:YP_010377160.1,GeneID:72551574;Name=OPG188;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp165%3B schlafen-like%3B similar to VACV-WR B4R and VACV-Cop B2R;gbkey=CDS;gene=OPG188;locus_tag=NBT03_gp158;product=Schlafen (1);protein_id=YP_010377160.1 +NC_063383.1 RefSeq gene 163333 165018 . + . ID=gene-NBT03_gp159;Dbxref=GeneID:72551575;Name=OPG189;gbkey=Gene;gene=OPG189;gene_biotype=protein_coding;locus_tag=NBT03_gp159;old_locus_tag=MPXV-M5312_HM12_Rivers-165 +NC_063383.1 RefSeq CDS 163333 165018 . + 0 ID=cds-YP_010377161.1;Parent=gene-NBT03_gp159;Dbxref=GenBank:YP_010377161.1,GeneID:72551575;Name=OPG189;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp166%3B ankyrin-like%3B similar to VACV-WR B5R and VACV-Cop B4R;gbkey=CDS;gene=OPG189;locus_tag=NBT03_gp159;product=Ankyrin repeat protein (25);protein_id=YP_010377161.1 +NC_063383.1 RefSeq gene 165122 166075 . + . ID=gene-NBT03_gp160;Dbxref=GeneID:72551576;Name=OPG190;gbkey=Gene;gene=OPG190;gene_biotype=protein_coding;locus_tag=NBT03_gp160;old_locus_tag=MPXV-M5312_HM12_Rivers-166 +NC_063383.1 RefSeq CDS 165122 166075 . + 0 ID=cds-YP_010377162.1;Parent=gene-NBT03_gp160;Dbxref=GenBank:YP_010377162.1,GeneID:72551576;Name=OPG190;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp167%3B palmitated 42 kDa glycoprotein located both on the membranes of infected cells and on EEV envelope%3B complement control protein-like%3B EEV type-1 membrane glycoprotein%2C protective antigen%3B similar to VACV-WR B6R and VACV-Cop B5R;gbkey=CDS;gene=OPG190;locus_tag=NBT03_gp160;product=EEV type-I membrane glycoprotein;protein_id=YP_010377162.1 +NC_063383.1 RefSeq gene 166161 166667 . + . ID=gene-NBT03_gp161;Dbxref=GeneID:72551577;Name=OPG191;gbkey=Gene;gene=OPG191;gene_biotype=protein_coding;locus_tag=NBT03_gp161;old_locus_tag=MPXV-M5312_HM12_Rivers-167 +NC_063383.1 RefSeq CDS 166161 166667 . + 0 ID=cds-YP_010377163.1;Parent=gene-NBT03_gp161;Dbxref=GenBank:YP_010377163.1,GeneID:72551577;Name=OPG191;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp168%3B Ankyrin-like protein%3B similar to VACV-WR B7R and VACV-Cop B6R;gbkey=CDS;gene=OPG191;locus_tag=NBT03_gp161;product=Ankyrin-like protein (46);protein_id=YP_010377163.1 +NC_063383.1 RefSeq gene 166731 167279 . + . ID=gene-NBT03_gp162;Dbxref=GeneID:72551578;Name=OPG192;gbkey=Gene;gene=OPG192;gene_biotype=protein_coding;locus_tag=NBT03_gp162;old_locus_tag=MPXV-M5312_HM12_Rivers-168 +NC_063383.1 RefSeq CDS 166731 167279 . + 0 ID=cds-YP_010377164.1;Parent=gene-NBT03_gp162;Dbxref=GenBank:YP_010377164.1,GeneID:72551578;Name=OPG192;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp169%3B Virulence%2C ER resident%3B similar to VACV-WR B8R and VACV-Cop B7R;gbkey=CDS;gene=OPG192;locus_tag=NBT03_gp162;product=Virulence protein;protein_id=YP_010377164.1 +NC_063383.1 RefSeq gene 167334 168137 . + . ID=gene-NBT03_gp163;Dbxref=GeneID:72551579;Name=OPG193;gbkey=Gene;gene=OPG193;gene_biotype=protein_coding;locus_tag=NBT03_gp163;old_locus_tag=MPXV-M5312_HM12_Rivers-169 +NC_063383.1 RefSeq CDS 167334 168137 . + 0 ID=cds-YP_010377165.1;Parent=gene-NBT03_gp163;Dbxref=GenBank:YP_010377165.1,GeneID:72551579;Name=OPG193;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp170%3B secreted IFN-g binding protein%3B Soluble IFN-g receptor-like protein%3B similar to VACV-WR B9R and VACV-Cop B8R;gbkey=CDS;gene=OPG193;locus_tag=NBT03_gp163;product=Soluble interferon-gamma receptor-like protein;protein_id=YP_010377165.1 +NC_063383.1 RefSeq gene 168230 168895 . + . ID=gene-NBT03_gp164;Dbxref=GeneID:72551580;Name=OPG195;gbkey=Gene;gene=OPG195;gene_biotype=protein_coding;locus_tag=NBT03_gp164;old_locus_tag=MPXV-M5312_HM12_Rivers-170 +NC_063383.1 RefSeq CDS 168230 168895 . + 0 ID=cds-YP_010377166.1;Parent=gene-NBT03_gp164;Dbxref=GenBank:YP_010377166.1,GeneID:72551580;Name=OPG195;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp171%3B shope fibroma virus T4 protein-like%3B ER-localized apoptosis regulator%3B similar to VACV-WR B10R and VACV-Cop B9R;gbkey=CDS;gene=OPG195;locus_tag=NBT03_gp164;product=Intracellular viral protein;protein_id=YP_010377166.1 +NC_063383.1 RefSeq sequence_feature 169001 169642 . + . ID=id-NC_063383.1:169001..169642;exon_number=OPG196;gbkey=misc_feature;number=OPG196 +NC_063383.1 RefSeq gene 169670 169972 . + . ID=gene-NBT03_gp165;Dbxref=GeneID:72551581;Name=OPG197;gbkey=Gene;gene=OPG197;gene_biotype=protein_coding;locus_tag=NBT03_gp165;old_locus_tag=MPXV-M5312_HM12_Rivers-171 +NC_063383.1 RefSeq CDS 169670 169972 . + 0 ID=cds-YP_010377167.1;Parent=gene-NBT03_gp165;Dbxref=GenBank:YP_010377167.1,GeneID:72551581;Name=OPG197;Note=Taxonomic breadth: chordopoxvirinae%3B Hypothetical protein%3B similar to VACV-Cop-B11R;gbkey=CDS;gene=OPG197;locus_tag=NBT03_gp165;product=CPXV205 protein;protein_id=YP_010377167.1 +NC_063383.1 RefSeq gene 170038 170886 . + . ID=gene-NBT03_gp166;Dbxref=GeneID:72551582;Name=OPG198;gbkey=Gene;gene=OPG198;gene_biotype=protein_coding;locus_tag=NBT03_gp166;old_locus_tag=MPXV-M5312_HM12_Rivers-172 +NC_063383.1 RefSeq CDS 170038 170886 . + 0 ID=cds-YP_010377168.1;Parent=gene-NBT03_gp166;Dbxref=GenBank:YP_010377168.1,GeneID:72551582;Name=OPG198;Note=Taxonomic breadth: poxviridae%3B protein kinase-like%3B similar to VACV-WR B11R and VACV-Cop B12R;gbkey=CDS;gene=OPG198;locus_tag=NBT03_gp166;product=Ser/thr kinase;protein_id=YP_010377168.1 +NC_063383.1 RefSeq gene 170988 172022 . + . ID=gene-NBT03_gp167;Dbxref=GeneID:72551583;Name=OPG199;gbkey=Gene;gene=OPG199;gene_biotype=protein_coding;locus_tag=NBT03_gp167;old_locus_tag=MPXV-M5312_HM12_Rivers-173 +NC_063383.1 RefSeq CDS 170988 172022 . + 0 ID=cds-YP_010377169.1;Parent=gene-NBT03_gp167;Dbxref=GenBank:YP_010377169.1,GeneID:72551583;Name=OPG199;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp173%3B serine protease inhibitor-like%2C SPI-2%3B inhibition of the IL-1b converting enzyme%3B apoptosis inhibition%3B Serpin 1%2C2%2C3%3B similar to VACV-WR B12R and VACV-Cop K2L;gbkey=CDS;gene=OPG199;locus_tag=NBT03_gp167;product=Serpin;protein_id=YP_010377169.1 +NC_063383.1 RefSeq gene 172150 172599 . + . ID=gene-NBT03_gp168;Dbxref=GeneID:72551584;Name=OPG200;gbkey=Gene;gene=OPG200;gene_biotype=protein_coding;locus_tag=NBT03_gp168;old_locus_tag=MPXV-M5312_HM12_Rivers-174 +NC_063383.1 RefSeq CDS 172150 172599 . + 0 ID=cds-YP_010377170.1;Parent=gene-NBT03_gp168;Dbxref=GenBank:YP_010377170.1,GeneID:72551584;Name=OPG200;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp174%3B Hypothetical protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR B13R and VACV-Cop C16L and B15R;gbkey=CDS;gene=OPG200;locus_tag=NBT03_gp168;product=Bcl-2-like protein;protein_id=YP_010377170.1 +NC_063383.1 RefSeq sequence_feature 172685 173697 . + . ID=id-NC_063383.1:172685..173697;exon_number=OPG201;gbkey=misc_feature;number=OPG201 +NC_063383.1 RefSeq sequence_feature 173744 174187 . - . ID=id-NC_063383.1:173744..174187;exon_number=OPG202;gbkey=misc_feature;number=OPG202 +NC_063383.1 RefSeq sequence_feature 174328 174456 . + . ID=id-NC_063383.1:174328..174456;exon_number=OPG203;gbkey=misc_feature;number=OPG203 +NC_063383.1 RefSeq gene 174532 175587 . + . ID=gene-NBT03_gp169;Dbxref=GeneID:72551585;Name=OPG204;gbkey=Gene;gene=OPG204;gene_biotype=protein_coding;locus_tag=NBT03_gp169;old_locus_tag=MPXV-M5312_HM12_Rivers-177 +NC_063383.1 RefSeq CDS 174532 175587 . + 0 ID=cds-YP_010377172.1;Parent=gene-NBT03_gp169;Dbxref=GenBank:YP_010377172.1,GeneID:72551585;Name=OPG204;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp177%3B cell surface antigen and secreted IFN-a%3B IFN-alpha/beta receptor glycoprotein%3B similar to VACV-WR B16R and VACV-Cop B19R;gbkey=CDS;gene=OPG204;locus_tag=NBT03_gp169;product=IFN-alpha/beta-receptor-like secreted glycoprotein;protein_id=YP_010377172.1 +NC_063383.1 RefSeq gene 175656 178019 . + . ID=gene-NBT03_gp170;Dbxref=GeneID:72551586;Name=OPG205;gbkey=Gene;gene=OPG205;gene_biotype=protein_coding;locus_tag=NBT03_gp170;old_locus_tag=MPXV-M5312_HM12_Rivers-178 +NC_063383.1 RefSeq CDS 175656 178019 . + 0 ID=cds-YP_010377173.1;Parent=gene-NBT03_gp170;Dbxref=GenBank:YP_010377173.1,GeneID:72551586;Name=OPG205;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp178%3B ankyrin-like%3B similar to VACV-WR B17R and VACV-Cop B20R;gbkey=CDS;gene=OPG205;locus_tag=NBT03_gp170;product=Ankyrin repeat protein (44);protein_id=YP_010377173.1 +NC_063383.1 RefSeq sequence_feature 178118 178916 . + . ID=id-NC_063383.1:178118..178916;exon_number=OPG206;gbkey=misc_feature;number=OPG206 +NC_063383.1 RefSeq gene 179266 180339 . + . ID=gene-NBT03_gp171;Dbxref=GeneID:72551587;Name=OPG208;gbkey=Gene;gene=OPG208;gene_biotype=protein_coding;locus_tag=NBT03_gp171;old_locus_tag=MPXV-M5312_HM12_Rivers-180 +NC_063383.1 RefSeq CDS 179266 180339 . + 0 ID=cds-YP_010377174.1;Parent=gene-NBT03_gp171;Dbxref=GenBank:YP_010377174.1,GeneID:72551587;Name=OPG208;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp180%3B serine protease inhibitor-like%2C SPI-1%3B apoptosis inhibition%3B Serpin 1%2C2%2C3%3B Actual start may be at position 179%2C074%3B annotated start of ORF is missing approx. 17 AA compared to CPXVs%3B similar to VACV-WR B19R and VACV-Cop K2L;gbkey=CDS;gene=OPG208;locus_tag=NBT03_gp171;product=Serpin;protein_id=YP_010377174.1 +NC_063383.1 RefSeq gene 180518 181090 . + . ID=gene-NBT03_gp172;Dbxref=GeneID:72551588;Name=OPG209;gbkey=Gene;gene=OPG209;gene_biotype=protein_coding;locus_tag=NBT03_gp172;old_locus_tag=MPXV-M5312_HM12_Rivers-181 +NC_063383.1 RefSeq CDS 180518 181090 . + 0 ID=cds-YP_010377175.1;Parent=gene-NBT03_gp172;Dbxref=GenBank:YP_010377175.1,GeneID:72551588;Name=OPG209;Note=Old product: MPXVgp181%3B Hypothetical protein%3B similar to VACV-WR B20R and VACV-Cop C14L;gbkey=CDS;gene=OPG209;locus_tag=NBT03_gp172;product=Virulence protein;protein_id=YP_010377175.1 +NC_063383.1 RefSeq gene 181356 186998 . + . ID=gene-NBT03_gp173;Dbxref=GeneID:72551589;Name=OPG210;gbkey=Gene;gene=OPG210;gene_biotype=protein_coding;locus_tag=NBT03_gp173;old_locus_tag=MPXV-M5312_HM12_Rivers-182 +NC_063383.1 RefSeq CDS 181356 186998 . + 0 ID=cds-YP_010377176.1;Parent=gene-NBT03_gp173;Dbxref=GenBank:YP_010377176.1,GeneID:72551589;Name=OPG210;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp182%3B Surface glycoprotein%3B putative membrane-associated glycoprotein%3B cadherin-like domain%3B similar to VACV-WR B21R;gbkey=CDS;gene=OPG210;locus_tag=NBT03_gp173;product=B22R family protein;protein_id=YP_010377176.1 +NC_063383.1 RefSeq sequence_feature 187317 187743 . + . ID=id-NC_063383.1:187317..187743;exon_number=OPG212;gbkey=misc_feature;number=OPG212 +NC_063383.1 RefSeq sequence_feature 187822 188298 . + . ID=id-NC_063383.1:187822..188298;exon_number=OPG213;gbkey=misc_feature;number=OPG213 +NC_063383.1 RefSeq sequence_feature 188458 188963 . + . ID=id-NC_063383.1:188458..188963;exon_number=OPG214;gbkey=misc_feature;number=OPG214 +NC_063383.1 RefSeq gene 189199 189660 . + . ID=gene-NBT03_gp174;Dbxref=GeneID:72551590;Name=OPG005;gbkey=Gene;gene=OPG005;gene_biotype=protein_coding;locus_tag=NBT03_gp174;old_locus_tag=MPXV-M5312_HM12_Rivers-184 +NC_063383.1 RefSeq CDS 189199 189660 . + 0 ID=cds-YP_010377177.1;Parent=gene-NBT03_gp174;Dbxref=GenBank:YP_010377177.1,GeneID:72551590;Name=OPG005;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp185%3B VAC B15R-like%3B Hypothetical protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR N1R and VACV-Cop C16L and B22R;gbkey=CDS;gene=OPG005;locus_tag=NBT03_gp174;product=Bcl-2-like protein;protein_id=YP_010377177.1 +NC_063383.1 RefSeq gene 190410 190940 . + . ID=gene-NBT03_gp175;Dbxref=GeneID:72551591;Name=OPG016;gbkey=Gene;gene=OPG016;gene_biotype=protein_coding;locus_tag=NBT03_gp175;old_locus_tag=MPXV-M5312_HM12_Rivers-186 +NC_063383.1 RefSeq CDS 190410 190940 . + 0 ID=cds-YP_010377184.1;Parent=gene-NBT03_gp175;Dbxref=GenBank:YP_010377184.1,GeneID:72551591;Name=OPG016;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp187%3B similar to VACV-WR N3R;gbkey=CDS;gene=OPG016;locus_tag=NBT03_gp175;product=Brix domain protein;protein_id=YP_010377184.1 +NC_063383.1 RefSeq long_terminal_repeat 190788 197209 . + . ID=id-NC_063383.1:190788..197209;gbkey=repeat_region;rpt_type=long_terminal_repeat +NC_063383.1 RefSeq gene 191054 192367 . + . ID=gene-NBT03_gp176;Dbxref=GeneID:72551592;Name=OPG015_dup;gbkey=Gene;gene=OPG015_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp176;old_locus_tag=MPXV-M5312_HM12_Rivers-187 +NC_063383.1 RefSeq CDS 191054 192367 . + 0 ID=cds-YP_010377179.1;Parent=gene-NBT03_gp176;Dbxref=GenBank:YP_010377179.1,GeneID:72551592;Name=OPG015_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp188%3B ankyrin-like%3B Ankyrin (CPXV-017)%3B similar to VACV-WR N4R;gbkey=CDS;gene=OPG015_dup;locus_tag=NBT03_gp176;product=Ankyrin repeat protein (39);protein_id=YP_010377179.1 +NC_063383.1 RefSeq gene 192603 194369 . + . ID=gene-NBT03_gp177;Dbxref=GeneID:72551593;Name=OPG003_dup;gbkey=Gene;gene=OPG003_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp177;old_locus_tag=MPXV-M5312_HM12_Rivers-188 +NC_063383.1 RefSeq CDS 192603 194369 . + 0 ID=cds-YP_010377180.1;Parent=gene-NBT03_gp177;Dbxref=GenBank:YP_010377180.1,GeneID:72551593;Name=OPG003_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp189%3B ankyrin-like%3B similar to VACV-WR J1R and VACV-Cop C19L;gbkey=CDS;gene=OPG003_dup;locus_tag=NBT03_gp177;product=Ankyrin repeat protein (25);protein_id=YP_010377180.1 +NC_063383.1 RefSeq gene 194459 195508 . + . ID=gene-NBT03_gp178;Dbxref=GeneID:72551594;Name=OPG002_dup;gbkey=Gene;gene=OPG002_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp178;old_locus_tag=MPXV-M5312_HM12_Rivers-189 +NC_063383.1 RefSeq CDS 194459 195508 . + 0 ID=cds-YP_010377181.1;Parent=gene-NBT03_gp178;Dbxref=GenBank:YP_010377181.1,GeneID:72551594;Name=OPG002_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp190%3B secreted TNF binding protein%3B TNF receptor (CrmB)%3B similar to VACV-WR J2R and VACV-Cop C22L;gbkey=CDS;gene=OPG002_dup;locus_tag=NBT03_gp178;product=Crm-B secreted TNF-alpha-receptor-like protein;protein_id=YP_010377181.1 +NC_063383.1 RefSeq gene 195635 196375 . + . ID=gene-NBT03_gp179;Dbxref=GeneID:72551595;Name=OPG001_dup;gbkey=Gene;gene=OPG001_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp179;old_locus_tag=MPXV-M5312_HM12_Rivers-190 +NC_063383.1 RefSeq CDS 195635 196375 . + 0 ID=cds-YP_010377182.1;Parent=gene-NBT03_gp179;Dbxref=GenBank:YP_010377182.1,GeneID:72551595;Name=OPG001_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp191%3B Chemokine binding protein (Cop-C23L)%3B most abundant secreted protein%3B CC-chemokine binding protein%3B similar to VACV-WR J3R and VACV-Cop C23L and B29R;gbkey=CDS;gene=OPG001_dup;locus_tag=NBT03_gp179;product=Chemokine binding protein;protein_id=YP_010377182.1 diff --git a/data_output/nextstrain/mpox/all-clades/unreleased/pathogen.json b/data_output/nextstrain/mpox/all-clades/unreleased/pathogen.json new file mode 100644 index 00000000..e3f51617 --- /dev/null +++ b/data_output/nextstrain/mpox/all-clades/unreleased/pathogen.json @@ -0,0 +1,212 @@ +{ + "alignmentParams": { + "excessBandwidth": 100, + "terminalBandwidth": 300, + "allowedMismatches": 8, + "windowSize": 40, + "minSeedCover": 0.1, + "gapAlignmentSide": "left" + }, + "attributes": { + "name": "Mpox virus (All clades)", + "reference accession": "NC_063383.1", + "reference name": "MPXV-M5312_HM12_Rivers" + }, + "compatibility": { + "cli": "3.0.0-alpha.0", + "web": "3.0.0-alpha.0" + }, + "deprecated": false, + "enabled": true, + "experimental": false, + "files": { + "changelog": "CHANGELOG.md", + "examples": "sequences.fasta", + "genomeAnnotation": "genome_annotation.gff3", + "pathogenJson": "pathogen.json", + "readme": "README.md", + "reference": "reference.fasta", + "treeJson": "tree.json" + }, + "official": true, + "qc": { + "frameShifts": { + "enabled": true, + "ignoredFrameShifts": [ + { + "codonRange": { + "begin": 3, + "end": 589 + }, + "geneName": "OPG003" + }, + { + "codonRange": { + "begin": 3, + "end": 589 + }, + "geneName": "OPG003_dup" + }, + { + "codonRange": { + "begin": 281, + "end": 285 + }, + "geneName": "OPG105" + }, + { + "codonRange": { + "begin": 227, + "end": 229 + }, + "geneName": "OPG164" + }, + { + "codonRange": { + "begin": 554, + "end": 560 + }, + "geneName": "OPG180" + }, + { + "codonRange": { + "begin": 42, + "end": 101 + }, + "geneName": "OPG197" + }, + { + "codonRange": { + "begin": 443, + "end": 443 + }, + "geneName": "OPG037" + }, + { + "codonRange": { + "begin": 57, + "end": 443 + }, + "geneName": "OPG037" + }, + { + "codonRange": { + "begin": 481, + "end": 483 + }, + "geneName": "OPG047" + }, + { + "codonRange": { + "begin": 482, + "end": 483 + }, + "geneName": "OPG047" + }, + { + "codonRange": { + "begin": 72, + "end": 76 + }, + "geneName": "OPG050" + }, + { + "codonRange": { + "begin": 369, + "end": 371 + }, + "geneName": "OPG153" + }, + { + "codonRange": { + "begin": 370, + "end": 371 + }, + "geneName": "OPG153" + }, + { + "codonRange": { + "begin": 166, + "end": 169 + }, + "geneName": "OPG191" + }, + { + "codonRange": { + "begin": 72, + "end": 222 + }, + "geneName": "OPG195" + }, + { + "codonRange": { + "begin": 208, + "end": 222 + }, + "geneName": "OPG195" + }, + { + "codonRange": { + "begin": 289, + "end": 346 + }, + "geneName": "OPG174" + } + ], + "scoreWeight": 20 + }, + "missingData": { + "enabled": true, + "missingDataThreshold": 20000, + "scoreBias": 1000 + }, + "mixedSites": { + "enabled": true, + "mixedSitesThreshold": 40 + }, + "privateMutations": { + "cutoff": 300, + "enabled": true, + "typical": 50, + "weightLabeledSubstitutions": 6, + "weightReversionSubstitutions": 6, + "weightUnlabeledSubstitutions": 1 + }, + "snpClusters": { + "clusterCutOff": 10, + "enabled": false, + "scoreWeight": 10, + "windowSize": 100 + }, + "stopCodons": { + "enabled": true, + "ignoredStopCodons": [ + { + "codon": 187, + "geneName": "OPG015_dup" + }, + { + "codon": 187, + "geneName": "OPG015" + }, + { + "codon": 21, + "geneName": "OPG176" + }, + { + "codon": 299, + "geneName": "OPG187" + }, + { + "codon": 48, + "geneName": "OPG059" + } + ], + "scoreWeight": 20 + } + }, + "schemaVersion": "3.0.0", + "version": { + "tag": "unreleased" + } +} diff --git a/data_output/nextstrain/mpox/all-clades/unreleased/reference.fasta b/data_output/nextstrain/mpox/all-clades/unreleased/reference.fasta new file mode 100644 index 00000000..0f1d13ac --- /dev/null +++ b/data_output/nextstrain/mpox/all-clades/unreleased/reference.fasta @@ -0,0 +1,2 @@ +>NC_063383.1 Monkeypox virus, complete genome +ATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTAACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATTTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAAACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACAAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTTGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAAT diff --git a/data_output/nextstrain/mpox/all-clades/unreleased/sequences.fasta b/data_output/nextstrain/mpox/all-clades/unreleased/sequences.fasta new file mode 100644 index 00000000..2ba90ecf --- /dev/null +++ b/data_output/nextstrain/mpox/all-clades/unreleased/sequences.fasta @@ -0,0 +1,18 @@ +>MPXV_USA_2022_MA001 | ON563414.2 +TATTATATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCRAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTTGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGAGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGAGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATATAATA +>ON676708 +ATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATTATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGTTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTTTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGNNNNATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATNNNAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAAT +>ON674051 +TATTATATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATANTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTATAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATTAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTTGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATTAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATTACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTTCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACAAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATAAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTTATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAAACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTTGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTTAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTAATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTAAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAAAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGAACGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAAATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATTTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATAGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAAACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCNNNTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGCGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATTATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTTTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCAAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTTAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACAATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTTATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAATGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATTACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGAAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTTCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACACCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGANNATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTTGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTTATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAANTATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATATAATA +>MT903339 +CGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCAAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTTGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCAATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACAAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCG +>MPXV-UK_P2 | MT903344.1 +TAATTAATTTAATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAANNNNNNNNNNTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATTAAATTAATTA +>Yambuku_DRC_1985 +ATAATATTAATGTACTAAAACTTATGTATTATTAATTTATCTAACTAAAGTTAGTAAATTATATACATAATTTTATAATTAATTTAATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGACGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCATTGGCATAAGGATATTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTGTAAAACTTTTTTATGAGACAAGAGAGAAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAACATTTTTGTTTTGCAAACCGGAATATAGTACCCGGTACACTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTTGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTAACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCGCTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCTGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCGCCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAGGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATGGGTAAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCCGTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACGGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGATCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGCGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACATTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATAGGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTTGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATGATGTCATTAACGACATCCGCCTTGTATATGATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAAATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACACGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATAAAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGAGAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAAATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGTACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAGTCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTGCCGACTCCATGGCGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGTAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGTCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATGTATAATCATCACTGTCGCTATCATTATTGCGTTTGTGTAGTTCTGCCCTATCATCTACATCACTGTCACTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCATACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTGTGTGCAACGTTAGAAATTCTAAATCTATAGTATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAACGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATACACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGCATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATAGGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAATACTAAGTATGCGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTATAATCATCTTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTGATGGTTATTTACTAACAGACATTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATATATATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTAGAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATGGTTATTAGTTAAGGGACCCGATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATCGATGTCAACACATTCTACATTTTTTAATCGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACATTGCTTTATTATATTTTATAAGAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACAATCATACATCAATTAACTCATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACGACAAATACCGATCGGTAATTGTCTCTGTCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTATTTTTGGAATCATAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATATTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTTAGATAATTGTCCTATATGCCGTACCCGTTTTAGAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCATCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTCTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTATTTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGCTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGGCAAATGTTTATAGTACTAAGAATTGGGCAAGTATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACGCATTATTCCGTGCGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATAAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGAGATGATATACAGATGCAATACGGTACCGCAATTTCGTGGTTGATAATCATCATACGCGTATCCGTACTCGTCATCCTCATAAAGAACACTGCAGCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTAATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTGTGTAATGGATTAGTGCCACTGTCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATATCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACCAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGAAGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTCCAACCACTATTATATGATTATAGTTTCTATTTTTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACACTATATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTACTAGTGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTTTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAACGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATTTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGACGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTATACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAATTTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTCGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAATACGAATAAAAACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAATTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTATTATACAGATGTATTACAGCCTCATATATTACGTAATATAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAACGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACGAATACCGACGGTGTGTGTTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGAAATCAGTTAGGAAGAAAAAATTATCTATCATCATCTATTGGATAACGTCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATGGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGATTCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGTTACATATCTCTTCTATATTATTGTTGATATATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATCTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACTTATACTCATCATCTGTTTTAGGAATCCATGTATTATTACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGTACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAGATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCCTCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCATGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATAATTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCGGCTGCCATGTATTTCCTGGAGAGCAAGTAGATGATGAGGAACCAGATAGTTTATATCCATACTTGCACTTAAAGTCTACATTGTAGTTGTATGAGTGTATGATCTTTTAAGCCGCTAGAAGTTTTCCGTTTGATATAGGATGTGGACATTTAACAATCTGACACGTGGGTGGATTGGACCATTCTCCTCCTGAACACATGACACCAGAGTTACCAATCAACGAATATCCACTATTGCAACTATAAGTTACAATGCTCCCATCGATATAAAAATCCTCGTATCCGTTATGTCTTCCGTTGGATATAGATGGAGGTGATTGGCATTTAACAGATTCGCAAATAGGTGCCTCAGGATTCCATACCATAGATCCAGTAGATCCTAATTCACAATACGATTTAGATTCACCGATCAAATGATATCCGCTATTACAAGAGTACGTTATACTAGAGCCAAAGTCTACTCCGCCAATATCAAGTTGGCCATTATCGATATCTCGAGGCGATGGGCATCTCCGTTTAATACATTGATTAAAGAGTGTCCATCCGGTACCGGTACATTTAGCATATATGGGTCCCATTTTTTGCTTTCTGTATCCAGGTAGACATAGATATTCTATAGTGTCTCCTATGTTGTAATTAGCATCAGTCTCTACACTATTCTTAAATTTCATATTAATGGGGCGTGACGGAATAGTACAGTATGATAGAACACATCCTATTCCCAACAATGTCAGGAACGTCACGCTCTCCACCTTCATATTTATTTATCCGTAAAATGTTATCCTGGACATCGTACAAATAATAAAAAGCCCATATATATGTTCGCTATTGTAGAAATTGTTTTTCACAGTTGCTCAAAAACAATGGCAGTGACTTATGAGTTAGTTACACTTTGGAGTCTCATCTTTAGTAAACATATCATAATATTCGATATTACGAGTTGACATATCGAACAAATTCCAAGTATTTGATTTTGGATAATATTCGTATTTTGCATCTGCTATAATTAAGATATAATCACCACAAGAACACACGAACGTCTTTCCTACATGGTTAAAGTACATGTACAATTCTATCCATTTGTCTTCCTTAACTATATATTTGTATAGATAATTACGAGTCTCATGAGTAATTCCAGTAATTGCATAGATGTCACCATCGTATTCTACAGCATAAACTATACTATGACGTCTAGGCATGGGAGACTTTTTTATCCAACGATTTTTAGTGAAACATTCCACATCGTTTAATACTACATATTTCTCATAGTGGTATAAACTCCACCCATTACATATATATCATCGTTTACGAATACTGATGCGCCTGAATATCTAGGAGTGATTAAGTTTGGAAGTCTTTTCCATTTCGAAGTGCCGTGTTTCAAATATTCTGCTATACCCGTTGAAATAGAAAATTCTAATCCTCCTATTACATATAACTTTCCATCGTTAACACAAGTACTAACTTCTGATTTTAACGACACATATTAGTAACCGTTTTCCATTTTTTTTGTTTTAAGATCTACCCGCGATACGGAATAAACATGTCTATTGTTAATCATGCCGCCAATAATGTATAGACAATTATGTAAAACATTTGCATCATAGAATTGTCTATCTGTATTACCGACTATCGTCCAATATTCTGTTCTAGGAGAGTAATGGGTTATTGTGGATATATAATCAGAGTTTTTAATGACTACTATATTATGTTTTATACCATTTCGTGTCACAGCTTTGTAGATTTGGATATAGTTAATCCCAACAATGCTATAGCATTGCATATAGCATTAGTCATAAACTTGGGATGTAAAATGTTGATGATATCTACATCGTTTGGATTTTTATGTATCCACTTTAATAATATTATAGCGTAACATCCTCATGATTTACGTTAACGTTTTCGTGTGATAAGATAGTGGTCAGTTCATCCTTTGATAATTTTCCAAATTCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGCATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTACTACAGGCGGAACATCAATTATTATGGCAGCGACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAAATAATTTCCCCATTGATAGAAAATATCACGCGTTCCATTCTCTTGAAGTACTATAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTTATAAAAAAAATCATTTCGACATTAATTCCTTTTTAAATTTCCGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGCGATAGAACCGCTAAAAAGCCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAGGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACATTCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGGTTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACGATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTATACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACGCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTATTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGAGGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAATATGCGACAATAGTACGATGCAATGAGTAAGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACATAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCTAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCGTTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGCACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATACATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAATAAAATAATTATTCCTTACATCGTACCATAAACAATATATTAAGTAGATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGCCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCGGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCTGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCGGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAATTTATTGATGTCTACACATCCTTTTGTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCTTGTTAACAGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCCGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCACCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCCAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACTACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGCACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTCATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGCCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCGCTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAATTGAATTGATGATATAGGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGTGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGCCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGTTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGCGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATTCCATCCCATTCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTACTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTTTGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCTAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGACGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATTGTAGAATTGACTATTATATTGCCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTATACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGTAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGATAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCATCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACATCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAACGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGCGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACACGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATACAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTCGTACACATCTTGATGTGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGCGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACCATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGCCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATTGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGGCCGGGCGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCCGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCAGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTGAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGACAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATAACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTATAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACGCATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATCAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAATTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAAGCATGTCCAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGTGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATGCCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCTAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACGCTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCTGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGAATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTGCATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGCGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAATGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATATTAACTATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCGATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATGAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGAGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGGCAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATTATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTCGGAACTGTACACCATAGTACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCGTAGAAATTTTTTAGAGAGAACTAACACAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCCGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCGTCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATTTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTCTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTGAGACATTGAAACTAGGATATATAAAATTTAAGTGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAATGAGTAAAATCAAACACAAAATCTTCGTTCAAACTTAATCTTATTAGAATATTAGTGGAAGAAAGATTCTATAATAATGAATGCAGAGATTATAAATGGAGAATAATTGGAACACAAGTTGATAAAATATTGATAGCTAAATATACAATAGATGCAATGTATCGCATAAGACCGATATATATAATACAAAGCAGTACAGATACAATGATGATGTAGAAAATGGATTCATTGGATTGGATAAACTAAAATTAAACATTGTTCATGATATAGTTGAATCATGTATACCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGTATTGACTTTGTTAGTGAATATGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAAGATAGTAAAAATAATTATTAGAATAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTTATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACCGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGATCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGATGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGAGGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACTGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCATATATTAAAAAATAACACATTTTTGATAAATGGAAACTGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGGGATATAAATATTATGGCAGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACCGGTCCCGTTCCAATAGGTATCAAAGATATAGATTACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAAGATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGCTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGACTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGACGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATGTATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCCAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACATAATTACCTGTTGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACTGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCATATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATACAAATAAGAAGGTACGGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGACATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATCGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACACGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGTTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACAACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATGACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCCAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGCGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCGACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACCACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTGATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGCGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGTATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGCAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCGCTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGATGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGATCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCGGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATAGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATAGATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCCTCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATACAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTTGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAACACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTCAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGCTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCATAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCGTCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTACTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAGCATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAGTCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACGAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGCGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAACTCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCCTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGCATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATATAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTACAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGTCTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGGTAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCTGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGTTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGAAGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAATGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAAATGGTGTTCCAGCTCGTGTGTTCTACGTGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAATCCCATTGGATAGATTTTTTGAAGGATATCTTAATGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATTTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCATTCTCTTCTATTTTTAAGCCGGCTATATATTCTGCTATATTGTTGCTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAGTTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTTTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCGCCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAACATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGCAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATGTTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGCGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGGCCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCGTCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTGCTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAACAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACGCATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATCGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTGCAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGTGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGAGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTGTTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAAACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGCATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTGTAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCTACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGGACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCTGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGCGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATTTACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGTGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATCGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATCACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGCATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTGTCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCGGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAATTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACATATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCCGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGTGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAGTGGAGTAGTAAACGTGTACATGACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAATTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCTGATAAGCTAACATCATACCCTCCTGTATATGTGAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGATAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCGCCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACACGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGTAACAATTTTTTGTTTAATGCATGTATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTGATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACACTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACATACTTGATATCTAAGAAATCCTTAATGATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATACGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAGCAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGAGAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATGTACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGTTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATACGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCGTTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACGCCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCGAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTACAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCGACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGTGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGATGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATATTGGACATCAATACGCCGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAATGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTATTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCATTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGCTGCTACGAGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTGCAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCATGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCATTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAAACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGAAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACAGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAAGATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCGCATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAGAGATTATATGATTACTAGACGACAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAGTCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGCCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAACGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACATTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGCGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTCCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGTGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGAAGAATATCTCTAACGAGTGATCAAATTATTGATACATTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCGAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCGATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGTATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACAGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGTGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAGTGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTTGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGTCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGACATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATAGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCCGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACCGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGACCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCATCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGTACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCGGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAATAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTGTGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAGGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCACCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCATAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCGGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTATAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTGGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGCAGACAGCCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGTCGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGACCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTACTTCAACGAGGAAGGTTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTTACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCAATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGGAAAAATCAATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATGCCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGCAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGTGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCATTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGACAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGCGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACTCATTTCGTTTATCATTATTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACCAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATACTTAGAATTTTAGGACGGATCAATGAGTAAGATTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATGGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCCAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACAATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGTAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATTGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGTGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGATCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACAGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTTTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATCGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCGCCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCGATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACAAGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCGGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAACAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTAATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAATATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAACAGTGTTATTAATATTGCCAAGTTATCAGATCTAAAAAAAACTATCTATACAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGACCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCAATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCGGAAACATCAGGAATCTGAACCCGCTTCCGTGCCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATGCAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCGAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAACGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTAGTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGCGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTCGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGCGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAGATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGAGTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGTTTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTGATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTGGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCCATTGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGCGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACACACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATTATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATCTTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCACATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTCTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTACGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATGCCTTTTCATTCCTCGAGTCTATCGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTCTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGGCACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACACAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCAGCGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTACATTGATTTCATTATTACGTCCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGTGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGTCGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTATCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTGAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCACTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATGACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATGTTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGTGAGACCTGATTCAGAACTCAACTCATCATTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTGGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCAGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCCGGTATCGGAGTGGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCATCATCTTCGATATTTATTTTGCTATCTTGATGATGTCCTGTATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATGTGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATCGTATCGAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCGATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATACGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCGTTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGACGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGTGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTGTCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGACAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACCATGTTCATAGTCATTAAGTCATTAACAAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGCACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGATATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTAGACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCACATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGGCATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTCATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGACATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACGAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGCGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACGCTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTACATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACAACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGATAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGCACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACCGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATGTCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGCGACGATTATCTTAATAAGCAATAACAAGATCATGAACACGATGATATAGAATCATCGGTTGTATCATTGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACGATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTAATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTTGTCTGTATTCATTATTAGACGAGTCACTGACTATTTGGATAGACACATATGCGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAATAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAACTAATTTCACAGTAGATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACATGGAATAATGATGGTATCATTACATGCTGTATACTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATGATGTGGTAACGGGTGTTATTAATGGGGCTGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAATGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATCAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGGGCTATTGGGTATGAAAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACAATTACAATACATTTTTATCATAACACTACTTCGGTTAGATGTTTTAGAAAAAAATAAATATCACTACCGTTCTTGTTTTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCGCACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCAACTATACATTCTTCTGTTAATTTTACTAGATCATCATGGGTCATAGAATTTATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACAGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGTGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGTCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATTGTATATTTTATTTTATTTTATATTTTATATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGATGATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGTTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCATGTCTCATTAAAAATTTGGTAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCACGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAAGATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATATCACACCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCTTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAAATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAATATTTATTCGGCATTGATGACACTGGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACCGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATAATTCGTCTACATGTTCTGCCGTAACCGACAGGGAAACGGATGTATAATTTTTTTATAGTGTGATGGATATGATGGATATGATGGATATGATATATGATGGATATTATGATGGATATGATGGATATTATGATGGATATGATGGATATGATGGATATGATAAATATGATAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGTATGTTTGACTTATGGTTAGACACGCATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCATCAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATCGAATTCCCAATATCATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTGGCATGTGACTTTTCTCTAAAGGATGATGTTGCCCGATCCTCTCTTAAATGAATCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACGTCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATATTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATATGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACATTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTGTTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCAATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTTAATAGTTACATATAAACTGAAAAATAAAATAATACTATTTTAGTTGGTGGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATATGATAAAAATAGATGACGATGACAAGACTCCTACCGGTGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATATGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGTCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGATCAACATGAACATAAAGATAGATGATATGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGAATTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTTATAGATTATATAAAGGTACAAAAACAGGATATCGTCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTATGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATACTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGATGGTTTAAGTTTAAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTGGTCAGTGTATAATAAATTATATGTAGGAGGAGGAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGGTACCACATAATTATATAATGTATAAATGCGAACCGGTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCGGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCGCGACTCCGGAACCAATTACTGATAATGTAGAAGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGACTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTTGTAGAAATATTTGGTATTACCACATTAATTATATTGTCGGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGACGAGAAGGTGTTGATTACCATTACTTAACAGAGAGGCAATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGCTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGGCCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACGTGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATTAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCTGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGTAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGCGAGTGCAATAGAAACACGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAGTGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTGGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGCTATATACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTATATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCTGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGGCAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCACGACTACCTCAAACTGGTAGAGAGAGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGTTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATACGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAGGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTCATGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTAAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGCGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCTCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCTATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCTGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACAGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATGCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGCGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGAACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACTGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAAGATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGCATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAAACTGCATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTTTAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCCATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCACATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTCTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGTGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGAGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCGATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGTGACTTTCAAGATGATGCGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTATAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATGTAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGATGATGGTGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATATATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAACGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGCATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCGACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCGTTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCGAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGTAGTGTTACGGATATCTGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTTAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGGAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTACTAACAGGTTAACATTTTTTTTAAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAGCACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGGCACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGGGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACTTTTCCCAGAAACAAACTTTTTTTACCTACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATGCATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTGAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACGCAGATATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGTGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTACATGCAGAGTATCGTTGAGACTTCCCACAACGGACGCTGACGTCTTTTGGATAAGTAATGGTATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACTGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTATAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATGCATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATTGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTGCCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCTGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATAAGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGTTCTCTGTCATATTCATACACCTGCATAAACTTTCTATACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAATTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTCAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAAACATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATATGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGCGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAATGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAATAATTATTATAATATAAGCGACAGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTGGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGCTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTTGTGCAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCAATCTCAATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGCTGCCGGATCTACGTATTTTAAAACAATGTTCACAACACCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATCTACAGATGTTCGATAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACGTATTAAAATGCACCGACTAAGAACGTAGAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAGGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCACTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTTGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATAACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAACGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCAAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATATATCGTTATATATCGTTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGTAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGTGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCCTTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCTAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGACAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGGCGTTTATAGATGTTAATGAGGAGTATACAGAAGCATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAAAAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTGTATTCGTGACTTCATCCATCGCTAGTCCATTTTACATTCCCGTTATTCCACCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGCATGTTTAATATGAAAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGGTAATCATGAATTTACAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGATGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCGCCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGATACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTGCATGGTAATATAGGATTTTTGGAAATAAATAATTGTTACAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAACTATTATATTTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACGCAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGGTGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGCGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTACAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCGCCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGGCCAAAAATTGAACCAGAATATGCGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGCAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACGCTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGACTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCCGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTACCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTGACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGCTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAACGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCGTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGGTACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTATTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACATAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGATCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAAAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGCAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATTACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACGCAGTGCAAGATTAATCTAGAAATCAAATGTAATTATGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATCATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAATGTGTCTCATATTATAATACACAAGAATTAAAGTGTTGTAAACTATCTAAGCCAGGAACATATTCAGATCATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATCTGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGCACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTGTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATTCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATAAACATCCCCTGAATCTGTACCTACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCGCGTATCGTTATACAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATGTACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTAACCTTCGTCTACCTTCACAATGGCCTTTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGGATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAATGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCGATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACGTGAAGATGATATCATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGAGGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACACAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAGTTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCGCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGTAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGAAGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCGCCATGGAGTCGGCAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGACTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTACAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATTTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTCTCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTTATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGTGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATTTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATCATATACAAGGCGGATGTCGTTAATGACATCATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCAACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACCTATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAATGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACGCCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGATCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCCGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAACGGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTTACCCATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCCTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGCGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCAGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGCGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTTAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCAAACGATTCAGACACCGCACCACGAATTAAAAAAGTGTACCGGGTACTATATTCCGGTTTGCAAAACAAAAATGTTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTTCTCTCTTGTCTCATAAAAAAGTTTTACAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAATATCCTTATGCCAATGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCGTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATTAAATTAATTATAAAATTATGTATATAATTTACTAACTTTAGTTAGATAAATTAATAATACATAAGTTTTAGTACATTAATATTAT +>Ivory_Coast_2012 +CCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAATAGAATAAAAATATTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTAAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATGGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCCGTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTCTCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGATTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATAGGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATGATGTCATTAACGACATCCGCCTTGTATATGATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCAGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCGCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTTCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATAAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTACTTATAAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACGATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCAATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCAATTTCAGTATATTCTTCGCCGTTATAAAAGTAATGTTGTTTAATTGTAGGACGGTTGTTAGTATAATCACATGAATAATAATATTCTAATTCCTCGTATTGACTACTTACAGATACTCGAAATAGTCTGAAAAATTCTTCAAAGATATTTTTATAAAGATCTAGGAAAAGTTTATTACCGACCATGAACGAGATAGATGGATAAATATCCTTTCCATCAAAGGTCATAATTGGATAATTGTCCAGCAATATATCTGCTGTATTAGTTATATCACTTCCATTTATTTTCAGATTGAAGTAATGTACTAGTTTGTGACAATTAACAAGATACAAAAGAGATGCCGATACTAATACGTAAATAGCTATACGCGAATCCATTGTTACCTTTTTTTATTTCATAGGTCTATTAATAAATATATGTATTACTTAAGACTAGAAAAATCAAAAGTAAGTTTTTGATATTTGATTCTTACTTATTGTGGGATTGTAGTTTACTTAGTAATTCATCTCTGAATCCTGATAAATCATGCATATCAATGATGCAACTACGCAGCAAACTAGTAGGAATATAGATATCTGGATATGTACGTAAATAGTCGATTATATCTTTTACAATACTATTAGTCCCTATTGCGTTATCTATATATCCATTAATAATATTACACAGTGGATACTTATGAGAAATATACCTCTTACAGATTTTTAACGATATATACTAGAAAGATATGTGTGTAGTACTGTATTACCTAAATTATCAGTCTCATTCAAATATTGCATGACTATTATCGAGAATTGCTATATCCCTCTATACTCGATGCATTTATTACAGTAATTCAATCCAGCTAACATAAGAGCCAATCTCAATGTTGGTTTAATTATATCATCTTCATGTAATAATAACGATGGAAACTTTCCAGTAGCGTAACACTTATCTAAGAAGGATATAATAACTATGTCTACATTATGTCTCTTATCGAGAATATTCTTAACGAGATATCCATAGCTATTCTGGTGCTAATTATTCCTATATTATATTCCACGAAAAATGATGAAGGCCATTCATCATAAGATGATAAAAAGTGTAGTGAGTAAGAGTATTAGTGAGAGAGCATGAAGGAGATTTAGTATTTAGCAGTGAGGATATGATCCAAGAGGGTGAGATAGTCGTTCTCGTTCAGAATCTTTCGCAGCATAAGTAGTATGTCGATATACTTATCATTGAAGACTCTTCCGGTGACAATAGCTGATTGAGTACAAAGTCCAATTATTGCACAAAGTTCTTTGGCGGTTTTCATGGAGTCATTTCTGATGAAACATTTAATGATCTCCACGCAATTGTCGATATTGTCCCACGGAAGTGAATCCGAGAACTCCTTCAACTCGCTACCAAATAGCTCCATTGCATCAATTCTGAAAGAGATGAGAAGCCTGTAGAGAGGCCCTGCGCTTTCTCTATGGGTCCATCTATGAGAAACCCACAGGATGTATTCAGTCAGACAATGTCTGACATCAGTCACGGTATTCAGGGAGTCCTTAGTAGCGTGGCAATGACAGGGACTGAACTGGGCACAAGGAGAGGCCATTGTGAAGGTAGACGAAGGTAACCTGATGGTAGACCTGTAGCCGTCTGTGCTTAATAGAGGGCTTTAATTTCCATTTTTAATGGTGTCGTGAATGAGGAATGAGAGTGTCTCTCGTCCTTGGTTTACATGGATCAGAGTGAGAAAAAATATCTTGTATATTATTAACTAACAACCTTGGTTTCTATCCATGTTTAAAAAATGACCTATATGTTCTTTATTAATTCTATTTTAAACTTTATCCTCAAGACTCCTGACAAAATTAAAATCCAGAAAGCAGCAAACAATCCTGTTACAAGTTTACTGAAATCTCTCTTTGATTGTAGAGTATATGTAGTCAGAGCAAGAAACACTGCAGTAGTCAACATGAAAGCTTGCATAACGATACGTGCATCATAGAAAGTAACAACAGAGGCCAGCGTTAGAGATTCTAACAGTGTAAATCCACAAAGTATGTACAGATTCAGGGGATGTTCATGTCTGTGTAAAGTCAATGCGAAAATCAAGCCTATAGATCCGAACATTGATGCCAATATTAGAACAGGACTCCCTTGTATAAATGTCCGATGCATTCAAAGTATAAAAATACTGCAGCTGTTGCCGTTGTTAAAGGAAATTGTAGAAAGGATACCGTAGACTTTTCTTAGAAATGCCATTCGTATGTACACGCTGGCAGACGCCACCGAGCTGTCATAGTTGAAGTCGTCCTCGATAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATATATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATAGTATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGATACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACATGTTGTCTATTATCTGTTTATAGGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTCTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCTGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCTTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATACATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAATGTTTCCAAATATATTACTGGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACATACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATCGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATCATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATATTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAATTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACCCGTTTTAGAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCATCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATAGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACGCAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGCTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGGCAAATGTTTATAGTACTAAGAATTGGGCAAGCATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATTTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTATATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTGTGTAATGGATTAGTGCCACTGTCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCACACAACTAATGTCATTAAATATCATTTTTGAATGTATATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCATATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGATGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGCTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATGGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACTTATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCATAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAGATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATAATTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTACTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGAGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTATAAGTAATTATAATATAATGAATGTAAAAAGGTTTATATATTCAATATTTTTTATAAAAAAAAAATCATTTCGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCTGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACATTCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATACCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACGCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATTTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTTCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCATTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATACATGGCTATCAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAATAAAATAATTATTCCTTACATCGTACCCATCAATATAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTAGATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGCCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGTCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCGGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCTGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCATCCCCATTTTGAATATTTTTATACGCTAATATACCGGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCTTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCACCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTCATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGCCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACTATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCATCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGTTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGCGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTTTGTTACAGTTTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATATATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGACGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCAACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGATAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGATGTTGAATAATCGTTATCATCATTTTGTAATTGTGACATCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAACGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACACGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTCGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGCTGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATTGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGGCCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCCGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATAGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGATGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGTTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACGCATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGAACTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGTATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCGCATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTATAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGTGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAACATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCGTCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGTACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAAGATAGTAAAAATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACCGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATACCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGTGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACCGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCCAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCGCAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCAACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGAAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGACATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGCGGACATTTTCTAGTTACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGCGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACGAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTACAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTGCCGAAAATAATCAGCACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGCGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTTCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCGCCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAACATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGCAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATAGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTATATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATCGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCATACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACTGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGAGATAAGAACATTATAATAATCAATAATATATCTTATATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAAACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGCATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTGTAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCTACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGCGTTATCGGGACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATTTACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTGTCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAATAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCTCCGCTTCTATTTACTCCCGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACATCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAGAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAGTGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTGAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACGTCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCGCCGCCACCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACACGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTGATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACTGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATACGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGAGAAATAATCATAAATTATTTCATTATCGTGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAATTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGAGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTACTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCGTTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATACCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTACAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCGACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGTGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGATGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTACCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGACCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTATGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGAGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTGCAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCAACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATCGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAAGATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAGAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGTAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGACAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAGTCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGCCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGCGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATACCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGAACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTGCTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGTCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGACATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAATACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGACCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATTATTAATACATTTATATCCAACATATGGTACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAGGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCACCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGCCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGTCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACGCATTTCGTTTATCATTGTTACTATTACTATTACTATTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTTTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCGCCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTTGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATACAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGACCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCAAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCTGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCGAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAGATAATAGCAATATTAGTTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGCGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGGAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATTATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATCTTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATCCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTCTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTACGTTTCTTTTTCTAGATCGACAATCTTTCTCAACATTTCATCCCCATGCCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCAACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCATCATTAGATTTACAGGCTGTTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTATAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGCAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTCCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATGACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATACATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATGTTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATAATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTGGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCGATATTTATTTTGCTATCTTGATAATGTCCTGTATCAGTTGCATTTTCAGCACTCGACTGAATATTAGCACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATGTGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCGAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATGATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCGTTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACATCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACAAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACGAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGCGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATATACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACCGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATGTAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAACACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATCAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACAATTACAATACATTTTTATCATAACACTACTTCGGTTAGATGTTTTAGAAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGTCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCACGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGTCATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCGCACCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGTACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCTTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAAATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACAGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTTTATAGTATGATGGATATGATGGATATGATGGATATGATGGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGTATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACTAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCATATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAACGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGACGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTGGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGTGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATATGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTTCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTAATTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGTATATACCTACTTCGTCACTTCCACACGCTCCAGAAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGGTGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTATAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCGCTACTTGGTTAGTGTGTATTATTCAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCTCATAGATTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACGATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGCCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAATATCCTCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATGTACCGACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTGGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGGAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGATATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCGCGACTCCGGAACCAATTACTGATAATGTAGAAGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGAATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGTGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTATGGAACTTCTAAAACAGCTGTAAATACAGCGGCTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGAGCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCACATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACGTGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGCGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTAAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAGTGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTGGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCACGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATACGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTCGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGCGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATGCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACTGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAAGATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGCATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACCGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCCATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTCTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTGATAAGGACATTGGATATGTGGAAAAGATGATGGTGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATGTTACAAATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCGACAACTGGACACGGGAACGTGGTATAAAGTATTTAGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCGAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTATAGAGTGTGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTAACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGGAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAGCACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGCCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGACCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATGCATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACGCAGATATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATAGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGCAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATGTATTACGAAGAAGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAATGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACATGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTATAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATGCATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATTGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGCATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAAACATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGAAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGCGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACGTGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTGGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACACCTATGATAGTGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACGTATTAAAATGCACCGACTAAGAACGTAGAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAGGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAACGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATATACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATAGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGGCAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTGCATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTAATTAACAACATAACTCTGACAAATATTATACGCAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGGTGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGATGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTACAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTATCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGGCCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACGCTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTTCCTGTCTTTATTGGAGATTACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTTCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATCTGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGTGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACTATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGATGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGGATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACCGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGGCCTTCATCATTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCGATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGTATATATCGTTAAAAATCTGTAAGAGGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTTACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGAAGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATTGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATCGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTTATAAGTAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTTATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGAACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGCGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCTGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATCATATACAAGGCGGATGTCGTTAATGACATCATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACCTATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAATCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGAGAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAACGGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCCATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTTACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAATATTTTTATTCTATTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGG +>ON843165 +TAATTAATTTAATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTTTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTTGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGAGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGAGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGNNNNNNNNGCNNNNNNNNNNNNNTTTCACGACGACCTCGATCNNNNNNNNNTNNCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATTAAATTAATTA +>KJ642617 +CGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATGATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATCGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCATACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAGATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTCGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTCGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACGCATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCGTCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAAGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACCGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCCAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACGAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGCATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGATGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATATATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGATGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGCGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGTCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACCCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAGATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGGCTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTCTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTACGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCRTCATCATSATCATCATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCGTTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACGAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGCGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACCGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGTCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCATGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAAATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCTATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCATGTAGGTCTTATCACGTGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAAGATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGGAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAGAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATCATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCG diff --git a/data_output/nextstrain/mpox/all-clades/unreleased/tree.json b/data_output/nextstrain/mpox/all-clades/unreleased/tree.json new file mode 100644 index 00000000..29ed85a7 --- /dev/null +++ b/data_output/nextstrain/mpox/all-clades/unreleased/tree.json @@ -0,0 +1 @@ +{"version":"v2","meta":{"title":"Nextclade reference tree for Mpox virus (All clades) dataset","updated":"2023-11-21","build_url":"https://github.com/nextstrain/mpox/nextclade","data_provenance":[{"name":"GenBank","url":"https://www.ncbi.nlm.nih.gov/genbank/"}],"maintainers":[{"name":"Cornelius Roemer","url":"https://neherlab.org"},{"name":"Richard Neher","url":"https://neherlab.org"},{"name":"Nextstrain team","url":"https://nextstrain.org"}],"display_defaults":{"color_by":"clade_membership","map_triplicate":false,"distance_measure":"div","tip_label":"strain_display","transmission_lines":false},"genome_annotations":{"OPG001":{"end":1575,"seqid":"resources/genome_annotation.gff3","start":835,"strand":"-","type":"gene"},"OPG001_dup":{"end":196375,"seqid":"resources/genome_annotation.gff3","start":195635,"strand":"+","type":"gene"},"OPG002":{"end":2751,"seqid":"resources/genome_annotation.gff3","start":1702,"strand":"-","type":"gene"},"OPG002_dup":{"end":195508,"seqid":"resources/genome_annotation.gff3","start":194459,"strand":"+","type":"gene"},"OPG003":{"end":4607,"seqid":"resources/genome_annotation.gff3","start":2841,"strand":"-","type":"gene"},"OPG003_dup":{"end":194369,"seqid":"resources/genome_annotation.gff3","start":192603,"strand":"+","type":"gene"},"OPG005":{"end":189660,"seqid":"resources/genome_annotation.gff3","start":189199,"strand":"+","type":"gene"},"OPG015":{"end":6156,"seqid":"resources/genome_annotation.gff3","start":4843,"strand":"-","type":"gene"},"OPG015_dup":{"end":192367,"seqid":"resources/genome_annotation.gff3","start":191054,"strand":"+","type":"gene"},"OPG016":{"end":190940,"seqid":"resources/genome_annotation.gff3","start":190410,"strand":"+","type":"gene"},"OPG019":{"end":8008,"seqid":"resources/genome_annotation.gff3","start":7580,"strand":"+","type":"gene"},"OPG021":{"end":10315,"seqid":"resources/genome_annotation.gff3","start":9587,"strand":"+","type":"gene"},"OPG022":{"end":10858,"seqid":"resources/genome_annotation.gff3","start":10478,"strand":"-","type":"gene"},"OPG023":{"end":12900,"seqid":"resources/genome_annotation.gff3","start":10918,"strand":"-","type":"gene"},"OPG024":{"end":13228,"seqid":"resources/genome_annotation.gff3","start":13034,"strand":"-","type":"gene"},"OPG025":{"end":15267,"seqid":"resources/genome_annotation.gff3","start":13375,"strand":"-","type":"gene"},"OPG027":{"end":16377,"seqid":"resources/genome_annotation.gff3","start":15925,"strand":"-","type":"gene"},"OPG029":{"end":17069,"seqid":"resources/genome_annotation.gff3","start":16602,"strand":"-","type":"gene"},"OPG030":{"end":17833,"seqid":"resources/genome_annotation.gff3","start":17213,"strand":"-","type":"gene"},"OPG031":{"end":18828,"seqid":"resources/genome_annotation.gff3","start":17878,"strand":"-","type":"gene"},"OPG034":{"end":20005,"seqid":"resources/genome_annotation.gff3","start":19361,"strand":"-","type":"gene"},"OPG035":{"end":20404,"seqid":"resources/genome_annotation.gff3","start":20051,"strand":"-","type":"gene"},"OPG036":{"end":21064,"seqid":"resources/genome_annotation.gff3","start":20531,"strand":"-","type":"gene"},"OPG037":{"end":22433,"seqid":"resources/genome_annotation.gff3","start":21105,"strand":"-","type":"gene"},"OPG038":{"end":23159,"seqid":"resources/genome_annotation.gff3","start":22497,"strand":"-","type":"gene"},"OPG039":{"end":24118,"seqid":"resources/genome_annotation.gff3","start":23264,"strand":"-","type":"gene"},"OPG040":{"end":25478,"seqid":"resources/genome_annotation.gff3","start":24351,"strand":"-","type":"gene"},"OPG042":{"end":27097,"seqid":"resources/genome_annotation.gff3","start":25823,"strand":"-","type":"gene"},"OPG043":{"end":27955,"seqid":"resources/genome_annotation.gff3","start":27125,"strand":"-","type":"gene"},"OPG044":{"end":28540,"seqid":"resources/genome_annotation.gff3","start":28091,"strand":"+","type":"gene"},"OPG045":{"end":29262,"seqid":"resources/genome_annotation.gff3","start":28603,"strand":"-","type":"gene"},"OPG046":{"end":29729,"seqid":"resources/genome_annotation.gff3","start":29274,"strand":"-","type":"gene"},"OPG047":{"end":31194,"seqid":"resources/genome_annotation.gff3","start":29746,"strand":"-","type":"gene"},"OPG048":{"end":32164,"seqid":"resources/genome_annotation.gff3","start":31205,"strand":"-","type":"gene"},"OPG049":{"end":33151,"seqid":"resources/genome_annotation.gff3","start":32195,"strand":"-","type":"gene"},"OPG050":{"end":33408,"seqid":"resources/genome_annotation.gff3","start":33181,"strand":"-","type":"gene"},"OPG051":{"end":33649,"seqid":"resources/genome_annotation.gff3","start":33425,"strand":"-","type":"gene"},"OPG052":{"end":33995,"seqid":"resources/genome_annotation.gff3","start":33801,"strand":"-","type":"gene"},"OPG053":{"end":34690,"seqid":"resources/genome_annotation.gff3","start":34052,"strand":"-","type":"gene"},"OPG054":{"end":35996,"seqid":"resources/genome_annotation.gff3","start":34677,"strand":"-","type":"gene"},"OPG055":{"end":37083,"seqid":"resources/genome_annotation.gff3","start":36019,"strand":"-","type":"gene"},"OPG056":{"end":39034,"seqid":"resources/genome_annotation.gff3","start":37127,"strand":"-","type":"gene"},"OPG057":{"end":40195,"seqid":"resources/genome_annotation.gff3","start":39077,"strand":"-","type":"gene"},"OPG058":{"end":40434,"seqid":"resources/genome_annotation.gff3","start":40213,"strand":"-","type":"gene"},"OPG059":{"end":40633,"seqid":"resources/genome_annotation.gff3","start":40484,"strand":"-","type":"gene"},"OPG060":{"end":41182,"seqid":"resources/genome_annotation.gff3","start":40706,"strand":"-","type":"gene"},"OPG061":{"end":41884,"seqid":"resources/genome_annotation.gff3","start":41189,"strand":"-","type":"gene"},"OPG062":{"end":42252,"seqid":"resources/genome_annotation.gff3","start":41947,"strand":"+","type":"gene"},"OPG063":{"end":43688,"seqid":"resources/genome_annotation.gff3","start":42249,"strand":"-","type":"gene"},"OPG064":{"end":45898,"seqid":"resources/genome_annotation.gff3","start":43685,"strand":"-","type":"gene"},"OPG065":{"end":46483,"seqid":"resources/genome_annotation.gff3","start":46022,"strand":"-","type":"gene"},"OPG066":{"end":47428,"seqid":"resources/genome_annotation.gff3","start":46649,"strand":"-","type":"gene"},"OPG068":{"end":49904,"seqid":"resources/genome_annotation.gff3","start":48201,"strand":"+","type":"gene"},"OPG069":{"end":50486,"seqid":"resources/genome_annotation.gff3","start":49986,"strand":"+","type":"gene"},"OPG070":{"end":51411,"seqid":"resources/genome_annotation.gff3","start":50590,"strand":"+","type":"gene"},"OPG071":{"end":54438,"seqid":"resources/genome_annotation.gff3","start":51418,"strand":"-","type":"gene"},"OPG072":{"end":54757,"seqid":"resources/genome_annotation.gff3","start":54470,"strand":"+","type":"gene"},"OPG073":{"end":55141,"seqid":"resources/genome_annotation.gff3","start":54752,"strand":"-","type":"gene"},"OPG074":{"end":57125,"seqid":"resources/genome_annotation.gff3","start":55128,"strand":"-","type":"gene"},"OPG075":{"end":57498,"seqid":"resources/genome_annotation.gff3","start":57172,"strand":"-","type":"gene"},"OPG076":{"end":57630,"seqid":"resources/genome_annotation.gff3","start":57523,"strand":"-","type":"gene"},"OPG077":{"end":58583,"seqid":"resources/genome_annotation.gff3","start":57645,"strand":"-","type":"gene"},"OPG078":{"end":58811,"seqid":"resources/genome_annotation.gff3","start":58590,"strand":"-","type":"gene"},"OPG079":{"end":59621,"seqid":"resources/genome_annotation.gff3","start":58812,"strand":"-","type":"gene"},"OPG080":{"end":62018,"seqid":"resources/genome_annotation.gff3","start":59703,"strand":"-","type":"gene"},"OPG081":{"end":62285,"seqid":"resources/genome_annotation.gff3","start":62046,"strand":"-","type":"gene"},"OPG082":{"end":63452,"seqid":"resources/genome_annotation.gff3","start":62304,"strand":"-","type":"gene"},"OPG083":{"end":64716,"seqid":"resources/genome_annotation.gff3","start":63445,"strand":"-","type":"gene"},"OPG084":{"end":66752,"seqid":"resources/genome_annotation.gff3","start":64722,"strand":"+","type":"gene"},"OPG085":{"end":68531,"seqid":"resources/genome_annotation.gff3","start":66756,"strand":"-","type":"gene"},"OPG086":{"end":68863,"seqid":"resources/genome_annotation.gff3","start":68528,"strand":"-","type":"gene"},"OPG087":{"end":69519,"seqid":"resources/genome_annotation.gff3","start":68857,"strand":"+","type":"gene"},"OPG088":{"end":69863,"seqid":"resources/genome_annotation.gff3","start":69489,"strand":"-","type":"gene"},"OPG089":{"end":71170,"seqid":"resources/genome_annotation.gff3","start":69866,"strand":"+","type":"gene"},"OPG090":{"end":71370,"seqid":"resources/genome_annotation.gff3","start":71179,"strand":"+","type":"gene"},"OPG091":{"end":71867,"seqid":"resources/genome_annotation.gff3","start":71370,"strand":"+","type":"gene"},"OPG092":{"end":72947,"seqid":"resources/genome_annotation.gff3","start":71832,"strand":"-","type":"gene"},"OPG093":{"end":73760,"seqid":"resources/genome_annotation.gff3","start":72978,"strand":"+","type":"gene"},"OPG094":{"end":74802,"seqid":"resources/genome_annotation.gff3","start":73780,"strand":"+","type":"gene"},"OPG095":{"end":75555,"seqid":"resources/genome_annotation.gff3","start":74803,"strand":"+","type":"gene"},"OPG096":{"end":75865,"seqid":"resources/genome_annotation.gff3","start":75587,"strand":"+","type":"gene"},"OPG097":{"end":76875,"seqid":"resources/genome_annotation.gff3","start":75841,"strand":"-","type":"gene"},"OPG098":{"end":77655,"seqid":"resources/genome_annotation.gff3","start":76900,"strand":"+","type":"gene"},"OPG099":{"end":78051,"seqid":"resources/genome_annotation.gff3","start":77665,"strand":"+","type":"gene"},"OPG100":{"end":78466,"seqid":"resources/genome_annotation.gff3","start":78008,"strand":"+","type":"gene"},"OPG101":{"end":79019,"seqid":"resources/genome_annotation.gff3","start":78486,"strand":"+","type":"gene"},"OPG102":{"end":80086,"seqid":"resources/genome_annotation.gff3","start":79085,"strand":"+","type":"gene"},"OPG103":{"end":80558,"seqid":"resources/genome_annotation.gff3","start":80001,"strand":"+","type":"gene"},"OPG104":{"end":81019,"seqid":"resources/genome_annotation.gff3","start":80618,"strand":"-","type":"gene"},"OPG105":{"end":84986,"seqid":"resources/genome_annotation.gff3","start":81126,"strand":"+","type":"gene"},"OPG106":{"end":85498,"seqid":"resources/genome_annotation.gff3","start":84983,"strand":"-","type":"gene"},"OPG107":{"end":86081,"seqid":"resources/genome_annotation.gff3","start":85512,"strand":"+","type":"gene"},"OPG108":{"end":87059,"seqid":"resources/genome_annotation.gff3","start":86085,"strand":"-","type":"gene"},"OPG109":{"end":89447,"seqid":"resources/genome_annotation.gff3","start":87060,"strand":"-","type":"gene"},"OPG110":{"end":90264,"seqid":"resources/genome_annotation.gff3","start":89632,"strand":"+","type":"gene"},"OPG111":{"end":91209,"seqid":"resources/genome_annotation.gff3","start":90265,"strand":"+","type":"gene"},"OPG112":{"end":91687,"seqid":"resources/genome_annotation.gff3","start":91247,"strand":"+","type":"gene"},"OPG113":{"end":94268,"seqid":"resources/genome_annotation.gff3","start":91731,"strand":"+","type":"gene"},"OPG114":{"end":94667,"seqid":"resources/genome_annotation.gff3","start":94227,"strand":"-","type":"gene"},"OPG115":{"end":95361,"seqid":"resources/genome_annotation.gff3","start":94660,"strand":"+","type":"gene"},"OPG116":{"end":96017,"seqid":"resources/genome_annotation.gff3","start":95361,"strand":"+","type":"gene"},"OPG117":{"end":98406,"seqid":"resources/genome_annotation.gff3","start":96049,"strand":"+","type":"gene"},"OPG118":{"end":100359,"seqid":"resources/genome_annotation.gff3","start":98446,"strand":"+","type":"gene"},"OPG119":{"end":100871,"seqid":"resources/genome_annotation.gff3","start":100386,"strand":"+","type":"gene"},"OPG120":{"end":101748,"seqid":"resources/genome_annotation.gff3","start":100834,"strand":"-","type":"gene"},"OPG121":{"end":102431,"seqid":"resources/genome_annotation.gff3","start":101790,"strand":"+","type":"gene"},"OPG122":{"end":103174,"seqid":"resources/genome_annotation.gff3","start":102428,"strand":"+","type":"gene"},"OPG123":{"end":105070,"seqid":"resources/genome_annotation.gff3","start":103175,"strand":"-","type":"gene"},"OPG124":{"end":105968,"seqid":"resources/genome_annotation.gff3","start":105105,"strand":"-","type":"gene"},"OPG125":{"end":107654,"seqid":"resources/genome_annotation.gff3","start":105999,"strand":"-","type":"gene"},"OPG126":{"end":108130,"seqid":"resources/genome_annotation.gff3","start":107678,"strand":"-","type":"gene"},"OPG127":{"end":108825,"seqid":"resources/genome_annotation.gff3","start":108151,"strand":"-","type":"gene"},"OPG128":{"end":109055,"seqid":"resources/genome_annotation.gff3","start":108822,"strand":"-","type":"gene"},"OPG129":{"end":111004,"seqid":"resources/genome_annotation.gff3","start":109070,"strand":"-","type":"gene"},"OPG130":{"end":111902,"seqid":"resources/genome_annotation.gff3","start":111057,"strand":"-","type":"gene"},"OPG131":{"end":112425,"seqid":"resources/genome_annotation.gff3","start":111940,"strand":"+","type":"gene"},"OPG132":{"end":113540,"seqid":"resources/genome_annotation.gff3","start":112422,"strand":"-","type":"gene"},"OPG133":{"end":115696,"seqid":"resources/genome_annotation.gff3","start":113564,"strand":"-","type":"gene"},"OPG134":{"end":116628,"seqid":"resources/genome_annotation.gff3","start":115750,"strand":"+","type":"gene"},"OPG135":{"end":116911,"seqid":"resources/genome_annotation.gff3","start":116609,"strand":"-","type":"gene"},"OPG136":{"end":119587,"seqid":"resources/genome_annotation.gff3","start":116912,"strand":"-","type":"gene"},"OPG137":{"end":120558,"seqid":"resources/genome_annotation.gff3","start":119602,"strand":"+","type":"gene"},"OPG138":{"end":121132,"seqid":"resources/genome_annotation.gff3","start":120560,"strand":"-","type":"gene"},"OPG139":{"end":121368,"seqid":"resources/genome_annotation.gff3","start":121156,"strand":"-","type":"gene"},"OPG140":{"end":121746,"seqid":"resources/genome_annotation.gff3","start":121474,"strand":"-","type":"gene"},"OPG141":{"end":121924,"seqid":"resources/genome_annotation.gff3","start":121763,"strand":"-","type":"gene"},"OPG142":{"end":122198,"seqid":"resources/genome_annotation.gff3","start":121914,"strand":"-","type":"gene"},"OPG143":{"end":123315,"seqid":"resources/genome_annotation.gff3","start":122182,"strand":"-","type":"gene"},"OPG144":{"end":123932,"seqid":"resources/genome_annotation.gff3","start":123318,"strand":"-","type":"gene"},"OPG145":{"end":125425,"seqid":"resources/genome_annotation.gff3","start":123947,"strand":"+","type":"gene"},"OPG146":{"end":125639,"seqid":"resources/genome_annotation.gff3","start":125406,"strand":"-","type":"gene"},"OPG147":{"end":125987,"seqid":"resources/genome_annotation.gff3","start":125640,"strand":"-","type":"gene"},"OPG148":{"end":127266,"seqid":"resources/genome_annotation.gff3","start":125986,"strand":"+","type":"gene"},"OPG149":{"end":127759,"seqid":"resources/genome_annotation.gff3","start":127196,"strand":"+","type":"gene"},"OPG150":{"end":128927,"seqid":"resources/genome_annotation.gff3","start":127779,"strand":"+","type":"gene"},"OPG151":{"end":132418,"seqid":"resources/genome_annotation.gff3","start":128924,"strand":"+","type":"gene"},"OPG153":{"end":137667,"seqid":"resources/genome_annotation.gff3","start":136138,"strand":"-","type":"gene"},"OPG154":{"end":138050,"seqid":"resources/genome_annotation.gff3","start":137718,"strand":"-","type":"gene"},"OPG155":{"end":138491,"seqid":"resources/genome_annotation.gff3","start":138051,"strand":"-","type":"gene"},"OPG156":{"end":139409,"seqid":"resources/genome_annotation.gff3","start":138492,"strand":"-","type":"gene"},"OPG157":{"end":139608,"seqid":"resources/genome_annotation.gff3","start":139372,"strand":"-","type":"gene"},"OPG158":{"end":139769,"seqid":"resources/genome_annotation.gff3","start":139641,"strand":"-","type":"gene"},"OPG159":{"end":140205,"seqid":"resources/genome_annotation.gff3","start":139768,"strand":"+","type":"gene"},"OPG160":{"end":141074,"seqid":"resources/genome_annotation.gff3","start":140172,"strand":"-","type":"gene"},"OPG161":{"end":141647,"seqid":"resources/genome_annotation.gff3","start":141102,"strand":"+","type":"gene"},"OPG162":{"end":142158,"seqid":"resources/genome_annotation.gff3","start":141652,"strand":"+","type":"gene"},"OPG163":{"end":142732,"seqid":"resources/genome_annotation.gff3","start":142202,"strand":"+","type":"gene"},"OPG164":{"end":143464,"seqid":"resources/genome_annotation.gff3","start":142778,"strand":"+","type":"gene"},"OPG165":{"end":144322,"seqid":"resources/genome_annotation.gff3","start":143516,"strand":"+","type":"gene"},"OPG166":{"end":144577,"seqid":"resources/genome_annotation.gff3","start":144398,"strand":"+","type":"gene"},"OPG167":{"end":145407,"seqid":"resources/genome_annotation.gff3","start":144574,"strand":"-","type":"gene"},"OPG170":{"end":146778,"seqid":"resources/genome_annotation.gff3","start":146113,"strand":"-","type":"gene"},"OPG171":{"end":147389,"seqid":"resources/genome_annotation.gff3","start":146988,"strand":"+","type":"gene"},"OPG172":{"end":148017,"seqid":"resources/genome_annotation.gff3","start":147427,"strand":"+","type":"gene"},"OPG173":{"end":148261,"seqid":"resources/genome_annotation.gff3","start":148037,"strand":"+","type":"gene"},"OPG174":{"end":149395,"seqid":"resources/genome_annotation.gff3","start":148355,"strand":"-","type":"gene"},"OPG175":{"end":149819,"seqid":"resources/genome_annotation.gff3","start":149442,"strand":"+","type":"gene"},"OPG176":{"end":150531,"seqid":"resources/genome_annotation.gff3","start":149809,"strand":"+","type":"gene"},"OPG178":{"end":152123,"seqid":"resources/genome_annotation.gff3","start":151509,"strand":"+","type":"gene"},"OPG180":{"end":154371,"seqid":"resources/genome_annotation.gff3","start":152692,"strand":"+","type":"gene"},"OPG181":{"end":155416,"seqid":"resources/genome_annotation.gff3","start":154412,"strand":"+","type":"gene"},"OPG185":{"end":159858,"seqid":"resources/genome_annotation.gff3","start":158917,"strand":"+","type":"gene"},"OPG187":{"end":161533,"seqid":"resources/genome_annotation.gff3","start":160622,"strand":"+","type":"gene"},"OPG188":{"end":163107,"seqid":"resources/genome_annotation.gff3","start":161596,"strand":"+","type":"gene"},"OPG189":{"end":165018,"seqid":"resources/genome_annotation.gff3","start":163333,"strand":"+","type":"gene"},"OPG190":{"end":166075,"seqid":"resources/genome_annotation.gff3","start":165122,"strand":"+","type":"gene"},"OPG191":{"end":166667,"seqid":"resources/genome_annotation.gff3","start":166161,"strand":"+","type":"gene"},"OPG192":{"end":167279,"seqid":"resources/genome_annotation.gff3","start":166731,"strand":"+","type":"gene"},"OPG193":{"end":168137,"seqid":"resources/genome_annotation.gff3","start":167334,"strand":"+","type":"gene"},"OPG195":{"end":168895,"seqid":"resources/genome_annotation.gff3","start":168230,"strand":"+","type":"gene"},"OPG197":{"end":169972,"seqid":"resources/genome_annotation.gff3","start":169670,"strand":"+","type":"gene"},"OPG198":{"end":170886,"seqid":"resources/genome_annotation.gff3","start":170038,"strand":"+","type":"gene"},"OPG199":{"end":172022,"seqid":"resources/genome_annotation.gff3","start":170988,"strand":"+","type":"gene"},"OPG200":{"end":172599,"seqid":"resources/genome_annotation.gff3","start":172150,"strand":"+","type":"gene"},"OPG204":{"end":175587,"seqid":"resources/genome_annotation.gff3","start":174532,"strand":"+","type":"gene"},"OPG205":{"end":178019,"seqid":"resources/genome_annotation.gff3","start":175656,"strand":"+","type":"gene"},"OPG208":{"end":180339,"seqid":"resources/genome_annotation.gff3","start":179266,"strand":"+","type":"gene"},"OPG209":{"end":181090,"seqid":"resources/genome_annotation.gff3","start":180518,"strand":"+","type":"gene"},"OPG210":{"end":186998,"seqid":"resources/genome_annotation.gff3","start":181356,"strand":"+","type":"gene"},"nuc":{"end":197209,"start":1,"strand":"+","type":"source"}},"colorings":[{"key":"clade_membership","title":"Clade","type":"categorical","scale":[["I","#4A8CC2"],["II","#71B486"],["IIa","#ABBD52"],["IIb","#DEA73C"]]},{"key":"gt","title":"Genotype","type":"categorical"},{"key":"outbreak","title":"Outbreak","type":"categorical","scale":[["hMPXV-1","#4C90C0"]]},{"key":"lineage","title":"Lineage","type":"categorical","scale":[["A","#5E1D9D"],["A.1","#4D22AE"],["A.1.1","#4531BC"],["B.1","#4041C7"],["B.1.1","#3F53CD"],["B.1.2","#4064CF"],["B.1.3","#4375CD"],["C.1","#4784C8"],["B.1.4","#4C91BF"],["B.1.5","#539CB4"],["B.1.6","#5AA5A7"],["B.1.7","#63AC9A"],["B.1.8","#6CB28C"],["B.1.9","#77B67E"],["B.1.10","#82BA71"],["B.1.11","#8FBC66"],["B.1.12","#9CBE5B"],["B.1.13","#A9BD53"],["B.1.14","#B5BD4C"],["B.1.15","#C1BA46"],["B.1.16","#CDB642"],["B.1.17","#D6B03F"],["B.1.18","#DEA73B"],["B.1.19","#E39B39"],["B.1.20","#E68D36"],["A.2","#E67C33"],["A.2.1","#E5692F"],["A.2.2","#E1532B"],["A.2.3","#DE3E27"],["A.3","#DB2823"]]},{"key":"date","title":"Collection Date","type":"categorical"},{"key":"host","title":"Host","type":"categorical"},{"key":"strain","title":"Strain name","type":"categorical"},{"key":"strain_display","title":"Pretty strain name","type":"categorical"},{"key":"region","title":"Region","type":"categorical","scale":[["Asia","#447CCD"],["Oceania","#5EA9A1"],["Africa","#8ABB6A"],["Europe","#BEBB48"],["South America","#E29E39"],["North America","#E2562B"]]},{"key":"country","title":"Country","type":"categorical","scale":[["Israel","#5E1D9D"],["Singapore","#4F1FAA"],["Vietnam","#4929B4"],["Taiwan","#4333BE"],["South Korea","#403FC6"],["Japan","#3F4CCB"],["Australia","#3E59CF"],["Sierra Leone","#4066CF"],["Liberia","#4272CE"],["C\u00f4te d'Ivoire","#447ECC"],["Benin","#4887C6"],["Nigeria","#4C91C0"],["Gabon","#5199B8"],["Cameroon","#56A0AF"],["Republic of the Congo","#5BA7A6"],["Central African Republic","#62AB9C"],["Democratic Republic of the Congo","#69B091"],["South Africa","#70B487"],["Portugal","#78B67E"],["Ireland","#80B974"],["Spain","#89BB6B"],["United Kingdom","#92BC63"],["France","#9BBE5B"],["Belgium","#A4BE56"],["Netherlands","#AEBD50"],["Switzerland","#B7BD4B"],["Germany","#C0BB47"],["Italy","#C8B843"],["Slovenia","#D0B441"],["Sweden","#D6AF3E"],["Austria","#DDAA3C"],["Czech Republic","#E0A23A"],["Slovakia","#E49938"],["Romania","#E68F36"],["Finland","#E68234"],["Brazil","#E67631"],["Peru","#E4672E"],["Colombia","#E2572B"],["Mexico","#DF4728"],["USA","#DD3826"],["Canada","#DB2823"]]}],"filters":["clade_membership","lineage","country","host","institution","region","strain_display","strain","date","outbreak"],"panels":["tree","entropy"],"extensions":{"nextclade":{"clade_node_attrs":[{"name":"outbreak","displayName":"Outbreak","description":""},{"name":"lineage","displayName":"Lineage","description":""}],"placement_mask_ranges":[{"begin":0,"end":1500},{"begin":133050,"end":133250},{"begin":136500,"end":136600},{"begin":140050,"end":140250},{"begin":146750,"end":147000},{"begin":150500,"end":150650},{"begin":169250,"end":169500},{"begin":169700,"end":169800},{"begin":173150,"end":173350},{"begin":179000,"end":179300},{"begin":190787,"end":197209}]}}},"tree":{"name":"NODE_0000000","node_attrs":{"div":0,"clade_membership":{"value":"outgroup"}},"branch_attrs":{"mutations":{"nuc":["T128C","T466C","C630A","T720C","A1093G","C1201T","A1504G","A1687G","A1813C","T1814G","T2086G","C2391A","T2554C","T3099G","A3420G","A3450G","G4691A","T4836G","G5751A","A6076G","A6146G","C6429T","T6430A","C6904T","T6976-","C6978T","T7005C","T7648C","T7810C","T7950G","A8066G","C8286T","T8422C","T8694G","A8893C","T8923C","T9161G","A9376G","T9509A","G9698A","A10267C","A10275G","C10641T","T10992C","T11439C","A11593G","A11624G","A12003G","C12324A","A12352G","A12380G","T12418G","A12712G","A12733G","T13135C","C13223A","G13348A","T13995C","G13999T","C14091T","T14431C","G15602A","T15794C","T16393G","A16406G","G16581A","G16608A","A16634G","T16788G","C17496T","T17800C","A18017T","A18312G","A18478C","A18769G","T18861A","T18953C","T19055C","T19290C","A19304T","T19367C","A19392C","T19457C","A19475G","A20605G","A20990T","A21034G","A21191G","T22575G","C22928T","T23080G","A23171G","T23172A","A23173G","G23175A","C23176A","A24032G","T24179C","T24222C","T24358G","G24719C","T25173G","G25212T","A25407G","G25769T","T25856C","G27215A","T27614C","T27949C","A28090C","T28175C","A28532T","A28548G","C28710T","C29446T","T29655C","T29758C","A30500T","G31039A","A31102G","G31144A","G31793A","G32364A","A32477C","T32867C","T33043C","T33102A","T33143C","A33656C","A33708C","T33963C","C34005T","A34295G","A34301C","T34685C","A35613G","T36049C","C37170T","A38067G","T39072A","T39248C","T40558G","T40565C","C40937T","C41967T","T42516A","A42769G","T43751C","A44972T","A45500G","A45584G","C45637A","A46217G","T46417C","A46427C","A46895G","G47140T","T47181C","G47735T","G48138A","C48148A","A48527C","T49223G","C49994T","C50595A","T51168C","T52354G","T52684C","T52938C","C52989A","A53156G","A53207C","G53257A","T55188C","A55203G","T55805C","T56531C","T58035G","T58131C","T58467C","T58965C","A59046G","T59256C","C59488T","A59709G","C60874G","A61056C","T62823C","T63156C","T63303C","G63976A","A64465G","T65352A","A65663G","A66263G","A66580G","A66761C","T67245C","T67550C","T67827C","G69675T","A72261G","A73076G","A73821G","G74303C","T74382C","A75790G","T76123C","A76198G","A76648G","A76911G","A78461C","A78641G","A78728C","A78942G","C79267T","C79502A","A79829G","G80756A","T80986C","A81063G","C81182T","T81463G","A81977G","C81989T","A82838T","T83360C","T83843C","A84333G","A84395G","T85163C","C85763T","A86225G","G86502T","A86535G","A87049G","T87501C","C87584T","A87735G","A88773G","T89214C","T89579G","A90493G","T90891C","A91023G","A91347G","T91489G","G92009A","A92102G","C92237T","C92516T","T93356C","T95469C","C95477A","A95795G","C96651T","G97572A","T98430G","A99212G","G99234A","A99683G","T99830C","A100261G","T100341C","T100562C","C102971A","A103051G","T103424G","C105126T","T106115C","A106857C","G107232A","C107394T","T107511G","A108793G","A109382G","G109580A","T110828G","T111539C","A111545G","A111591T","T111716C","G113747A","A114458G","T116583C","A116643T","G116660A","G117014A","T117725G","T118520C","C120174A","C120252T","T120363C","A120965G","A121082G","C121453A","A121711G","T122049C","G122422A","T124687C","T124737C","G124988C","G125047A","A125334G","A125556G","A126255G","T126923G","T126969C","T127859C","A128076G","T128546G","A130030G","T131806C","T132118C","A132719C","T133099C","T133145C","A133201G","T133280C","A133328G","A133455G","T133733C","T133966C","A134233T","A134491G","T134765C","A134884G","A135706G","T136190G","A136486C","A136498G","T136555C","G136558C","A136596G","A136604G","A136687G","A136870G","T137026G","T137377C","A137627G","T137731C","A137925G","T138513C","G138654A","T138746C","T139285G","T139539C","A139771G","T139874C","A141300G","T141364C","A142450C","A143108G","T143392C","T143426C","C143997T","T144049C","T145074C","T145088G","T145336C","T145523G","A145551C","A145803C","G146098T","A146215G","A146434G","C146446T","C146687T","T147860C","T147904G","G148126A","G149765T","G149878A","C150132T","G150153A","T150444C","T150488C","T150513C","A150545G","C150756T","A150780G","A151320G","C151341A","A151923G","T152967A","A153645G","A154405G","T154408C","C154702T","C154975T","C155479A","A155843G","T156426C","A156512G","A156954G","T156978C","G157273T","A157437G","T157490C","A158175C","A158398G","A158403G","A158511G","T158668G","T158787G","A159351G","A159415G","C159447A","T159530C","C159741T","A159780G","T160152C","A160867G","A160924T","A161519T","T161574C","A161799G","A162291G","C162639T","A162720G","T162828C","T163467C","T164848C","G165006A","T165304C","C165691T","T166399G","T166934C","C167126T","T167656G","T167858C","T168185C","A168277C","G168588C","C168769T","C168987A","A169081G","T169142C","A169353G","A169603G","T169721A","T170037C","A170248G","A170335G","A170435G","A171675G","T172087A","A172188G","A172304G","A172980G","A173102G","A173150G","T173441C","A173472G","C173569T","A173809G","T173810C","C173882T","A173974G","T174170C","G174301A","C175065A","C175964T","T176160C","C176453T","G176701A","G176715A","T177167G","T177517C","T177724C","T178237C","T178275C","A178311C","A178395G","A178423G","A178540G","G178639A","G178791A","G178887A","G179023A","C179226T","C179478T","A179538C","G179589T","T179690C","T180197C","A181350G","T181364A","A181994G","T182033C","A182348C","A182443G","A182491G","T183008C","A183491G","A183695G","T183696C","T183718C","T183920C","A184137G","T184286C","G185268A","A185762G","T185900C","T186077C","T186466G","A186505G","T187080A","T187345C","C187421T","A187498G","T187839C","G187914A","T187964C","A188096C","T188537C","G188726A","A188747C","A188812G","T189179A","A189418G","T189811G","A189909C","T190098G","G190154A","A190396T","G190404T","T190596G","A190648T","C190772A","A191051G","T191064C","G191401A","C191459T","A192374C","C192471T","C192519T","T193760C","T193790C","A194111C","G194819T","A195124C","A195396C","T195397G","T195523C","T195706C","G196009A","T196117C","A196490G","A196744G"],"OPG002":["A121S","N313T"],"OPG002_dup":["A121S","N313T"],"OPG005":["N74D"],"OPG015":["V4A","L136F"],"OPG015_dup":["V4A","L136F"],"OPG016":["S63A","E80V","D121E"],"OPG019":["M124R"],"OPG021":["V38I","K230R"],"OPG022":["G73D"],"OPG023":["V174A","A193S","Y300H","V426A","T488A","K637E"],"OPG024":["S32G"],"OPG025":["E393K","I425V"],"OPG029":["C146R"],"OPG030":["N12D","S113N"],"OPG031":["D117E","M271K"],"OPG034":["L205R"],"OPG036":["S11P","D25E"],"OPG037":["C415R"],"OPG038":["H27P","V78I"],"OPG040":["P254A","Y374S"],"OPG043":["T3A"],"OPG044":["M148L"],"OPG045":["A185T"],"OPG046":["S95N"],"OPG047":["I232K"],"OPG049":["E17V","M37V","T263M"],"OPG054":["R438G"],"OPG056":["V323A","C622Y"],"OPG059":["I26L"],"OPG063":["V307A"],"OPG064":["A88S"],"OPG065":["N23D"],"OPG066":["K83R","H97N"],"OPG068":["D341E"],"OPG071":["L411W","I428T","A484S","I501V"],"OPG074":["N199D","I441V"],"OPG079":["C45Y"],"OPG080":["D321E","C382S"],"OPG084":["S211T","Q620R"],"OPG085":["T328A","F591V"],"OPG094":["R175T"],"OPG096":["I68M"],"OPG100":["K152Q"],"OPG101":["T153A"],"OPG102":["I249V"],"OPG104":["T12A"],"OPG105":["V113G","I1070V"],"OPG108":["V4A"],"OPG109":["A622T"],"OPG111":["I77V"],"OPG112":["H34R"],"OPG118":["K256R","N413S","V462A","K606E"],"OPG125":["I514V"],"OPG130":["T63A","T122A"],"OPG135":["V90E"],"OPG145":["I264T","A348P","Q463R"],"OPG148":["I313S"],"OPG150":["N100D","D256E"],"OPG153":["M14T","I355T","Y358H","I370M","I371M","Q493P"],"OPG154":["H107R"],"OPG156":["Y42S","T222A"],"OPG157":["M24V"],"OPG159":["T2A","L36S"],"OPG161":["K67E","V88A"],"OPG164":["I111V","Y217H"],"OPG165":["S161L"],"OPG167":["Y107S","I112V"],"OPG170":["G31D","M111I"],"OPG172":["M145T","Y160D"],"OPG176":["D24N","L227S"],"OPG178":["I139V"],"OPG185":["T167A","D177E","I205T"],"OPG187":["K300*"],"OPG189":["C506R"],"OPG191":["F80C"],"OPG193":["I108R"],"OPG195":["C120S"],"OPG197":["S18T"],"OPG198":["N71D","I100V","Q133R"],"OPG199":["K230E"],"OPG200":["D52G"],"OPG204":["N178K"],"OPG205":["W169R","C349Y","G354S","V621A","V690A"],"OPG208":["I142T","V311A"],"OPG210":["F3L","K331N","H363R","D379G","S781P","V788A","T928A","A1305T","L1704R","D1717G"]},"labels":{"aa":"OPG002: A121S, N313T; OPG002_dup: A121S, N313T; OPG005: N74D; OPG015: V4A, L136F; OPG015_dup: V4A, L136F; OPG016: S63A, E80V, D121E; OPG019: M124R; OPG021: V38I, K230R; OPG022: G73D; OPG023: V174A, A193S, Y300H, V426A, T488A, K637E; OPG024: S32G; OPG025: E393K, I425V; OPG029: C146R; OPG030: N12D, S113N; OPG031: D117E, M271K; OPG034: L205R; OPG036: S11P, D25E; OPG037: C415R; OPG038: H27P, V78I; OPG040: P254A, Y374S; OPG043: T3A; OPG044: M148L; OPG045: A185T; OPG046: S95N; OPG047: I232K; OPG049: E17V, M37V, T263M; OPG054: R438G; OPG056: V323A, C622Y; OPG059: I26L; OPG063: V307A; OPG064: A88S; OPG065: N23D; OPG066: K83R, H97N; OPG068: D341E; OPG071: L411W, I428T, A484S, I501V; OPG074: N199D, I441V; OPG079: C45Y; OPG080: D321E, C382S; OPG084: S211T, Q620R; OPG085: T328A, F591V; OPG094: R175T; OPG096: I68M; OPG100: K152Q; OPG101: T153A; OPG102: I249V; OPG104: T12A; OPG105: V113G, I1070V; OPG108: V4A; OPG109: A622T; OPG111: I77V; OPG112: H34R; OPG118: K256R, N413S, V462A, K606E; OPG125: I514V; OPG130: T63A, T122A; OPG135: V90E; OPG145: I264T, A348P, Q463R; OPG148: I313S; OPG150: N100D, D256E; OPG153: M14T, I355T, Y358H, I370M, I371M, Q493P; OPG154: H107R; OPG156: Y42S, T222A; OPG157: M24V; OPG159: T2A, L36S; OPG161: K67E, V88A; OPG164: I111V, Y217H; OPG165: S161L; OPG167: Y107S, I112V; OPG170: G31D, M111I; OPG172: M145T, Y160D; OPG176: D24N, L227S; OPG178: I139V; OPG185: T167A, D177E, I205T; OPG187: K300*; OPG189: C506R; OPG191: F80C; OPG193: I108R; OPG195: C120S; OPG197: S18T; OPG198: N71D, I100V, Q133R; OPG199: K230E; OPG200: D52G; OPG204: N178K; OPG205: W169R, C349Y, G354S, V621A, V690A; OPG208: I142T, V311A; OPG210: F3L, K331N, H363R, D379G, S781P, V788A, T928A, A1305T, L1704R, D1717G","clade":"outgroup"}},"children":[{"name":"reconstructed_ancestral_mpox","node_attrs":{"div":0,"clade_membership":{"value":"outgroup"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000001","node_attrs":{"div":9,"clade_membership":{"value":"outgroup"}},"branch_attrs":{"mutations":{"nuc":["T607-","T608-","T609-","T4694-","T4695-","T6429C","A6430T","T6978-","A8055-","T8499-","T8993-","A16608-","G23171-","A23172T","G23173A","A23175G","A23176C","C29758T","A32210-","C32211-","G32212-","A33199-","T33414-","A39072T","T132813-","T133090-","T133091-","T133092-","T133093-","T133094-","T133095-","T133096-","T133097-","T133098-","C133099-","T133100-","T133101-","T133102-","T133177-","T133179-","T133180-","T133181-","T133183-","A133185-","A133186-","C136555-","C136558-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","A156415-","A156548-","A157678-","A157679-","A157680-","A157681-","T157682-","T157683-","T157684-","T157685-","A157686-","A157687-","A157691-","T157692-","A157694-","T157695-","A157696-","A158027-","T158028-","A158029-","A158170-","T166656-","T166657-","A169721-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","A173501-","T173502-","T173745-","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","T179226C","A181114-","T181115-","T181116-","T181119-","T181120-","A181121-","T181122-","A187080-","A189179T","T189744-","T190396A","T192471-","A192515-","A192516-","A196615-","A196616-","A196617-"],"OPG049":["R314-"],"OPG153":["M370I","M371I"],"OPG159":["N124-","Y125-","N126-"],"OPG191":["F166-"]},"labels":{"aa":"OPG049: R314-; OPG153: M370I, M371I; OPG159: N124-, Y125-, N126-; OPG191: F166-"}},"children":[{"name":"NODE_0000002","node_attrs":{"div":262,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G475A","T600-","T601-","T602-","T603-","T604-","T605-","T606-","G749A","A1309G","G2239-","A2240-","C2241-","C2659T","C3143T","G4042A","C4693-","A4696-","A4697-","C4698-","T4699-","A4700-","A4701-","C4702-","T4703-","T4704-","A4705-","T4706-","G4707-","A4708-","C4709-","T4710-","T4711-","A4712-","A4713-","C4714-","T4715-","A4716-","A4717-","C4718-","T4719-","T4720-","A4721-","T4722-","G4723-","A4724-","C4725-","T4726-","T4727-","A4728-","A4729-","C4730-","T4731-","A4732-","A4733-","C4734-","T4735-","T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","A4748-","A4749-","C4750-","T4751-","T4752-","A4753-","T4754-","G4755-","A4756-","C4757-","T4758-","T4759-","A4760-","A4761-","C4762-","T4763-","A4764-","A4765-","C4766-","T4767-","T4768-","A4769-","T4770-","G4771-","A4772-","C4773-","T4774-","T4775-","C5809T","T6159C","T6432-","C6433-","-6976T","-6978C","G7021-","C7022-","T7023-","C7024-","T7025-","C7026-","C7148-","T7149-","A7150-","T7151-","G7205A","T7405-","T7411C","G8277A","T8328-","T8329-","A8421-","C8422-","A8423-","T8424-","A8471-","C8603A","A8810G","A8830G","T8919-","G9139A","A9282-","C9404T","A9529-","C10242T","A11097T","C11625T","A11991G","G12128A","C12574A","A13276-","T13353-","C14647T","T15281C","A15549-","T15550-","A15657T","A15872-","C15883A","C16002T","G16102A","T16239C","T16609-","C16610-","A16611-","T16612-","C16613-","G17525A","A18055-","C18056-","C18057-","C18107T","G18590A","A19086G","T19282G","C22003T","C23283T","C23648T","A24310-","C24338-","A25528T","G25777A","C27692T","T28278C","A28415G","A28590-","G28591-","T28592-","G28593-","T28594-","T28595-","A28596-","A28597-","A28598-","A28599-","A28600-","A28601-","A28602-","T28603-","T28604-","A28605-","T28606-","C28607-","C28608-","T29029C","G29923A","C30730T","C31081T","C31529T","G31955A","C33159T","C35352A","G36445A","T39076-","G40501A","A41207G","C41735T","A41861G","T41935-","C44387T","G44966A","G46303T","G46421A","C46435T","A46506-","C46507-","A46508-","T46583G","T46596-","G46610A","T46648-","T46760C","A47576-","A47700-","C47701-","G47966A","C48041T","G48062T","A48166-","G48167-","T48168-","C48392T","C48951T","C49139T","G49859T","C49957T","C50500-","T50501-","T50575-","A50576-","C51202T","G53269T","G54352T","G54497A","T57433C","C57572T","G57622A","A58872G","T59648C","G60274T","A60457G","G60753A","G62250A","C62649T","T66650C","G67611A","A68297T","A68795G","C69896T","C70774A","C71035T","A71205G","G71553A","G71587A","A72217T","C72231T","C73350T","T82688C","T84290C","C84927T","A86247G","G86728A","C87560T","T88356A","G88746A","A89276G","C90820T","G93339A","C94061T","G94623A","G95280A","C97134A","G97408A","G98202A","A98856G","G100445A","T101536C","C101694T","C103006A","C103764T","C103805A","C104134T","A104556G","C104840T","G106554A","G107118C","C107322A","G107764A","G109874A","G111095T","A111303G","G111715A","G112206A","A112221G","C112455T","A113916G","G113924A","T114770C","C115676T","A116427C","T116735C","C117047T","G118640A","A118740T","C118789T","C118903T","G119474A","G123382A","A124691G","C124714A","A125365G","G126603A","T127137C","A128940T","A129767G","C131809T","G132286A","G132887A","T133084C","T133088-","T133089-","C133178-","C133182-","C133184-","T133224C","G133368A","T133493-","C133494-","G133495-","G133496-","T133497-","C133498-","C133499-","A133500-","T133501-","G133502-","T133503-","C133504-","T133505-","C133506-","C133507-","A133508-","T133509-","T133510-","G133511-","C133512-","T133513-","A133514-","C133515-","A133516-","C133517-","C133518-","A133519-","C133520-","C133521-","A133522-","T133523-","T133524-","A133525-","G133526-","A133527-","T133528-","T133529-","T133530-","A133531-","C133532-","A133533-","G133534-","G133535-","C133536-","T133537-","G133538-","C133539-","T133540-","A133541-","G133542-","T133543-","T133544-","G133545-","T133546-","C133547-","G133548-","T133549-","T133550-","C133551-","G133552-","A133553-","G133554-","A133555-","T133556-","C133557-","A133558-","G133559-","A133560-","A133561-","A133562-","T133563-","A133564-","C133565-","G133566-","T133567-","G133568-","T133569-","T133570-","T133571-","T133572-","C133573-","T133574-","T133575-","G133576-","G133577-","A133578-","A133579-","T133580-","G133581-","G133582-","A133583-","T133584-","T133585-","T133586-","C133587-","G133588-","T133589-","C133590-","G133591-","A133592-","T133593-","G133594-","T133595-","A133596-","C133597-","T133598-","T133599-","G133600-","T133601-","C133602-","A133603-","T133604-","G133605-","A133606-","T133607-","T133608-","G133609-","G133610-","C133611-","A133612-","T133613-","C133614-","G133615-","A133616-","A133617-","A133618-","C133619-","A133620-","C133621-","T133622-","T133623-","A133624-","T133625-","T133626-","A133627-","A133628-","G133629-","T133630-","T133631-","C133632-","T133633-","T133634-","T133635-","T133636-","T133637-","T133638-","T133639-","C133640-","A133641-","A133642-","T133643-","T133644-","C133645-","T133646-","A133647-","C133648-","G133649-","A133650-","T133651-","T133652-","T133653-","T133654-","A133655-","T133656-","T133657-","T133658-","C133659-","T133660-","T133661-","T133662-","C133663-","G133664-","C133665-","G133666-","A133667-","G133668-","T133669-","C133670-","A133671-","A133672-","T133673-","T133674-","C133675-","C133676-","C133677-","T133678-","C133679-","C133680-","T133681-","G133682-","T133683-","A133684-","G133685-","T133686-","A133687-","A133688-","C133689-","T133690-","A133691-","T133692-","C133693-","A133694-","G133695-","T133696-","T133697-","T133698-","T133699-","G133700-","T133701-","C133702-","A133703-","G133704-","A133705-","T133706-","T133707-","C133708-","A133709-","C133710-","G133711-","C133712-","T133713-","C133714-","T133715-","C133716-","T133717-","A133718-","C133719-","G133720-","T133721-","A133722-","G133723-","A133724-","C133725-","T133726-","T133727-","T133728-","C133729-","T133730-","T133731-","G133732-","C133733-","A133734-","A133735-","G133736-","T133737-","T133738-","A133739-","C133740-","T133741-","A133742-","A133743-","T133744-","T133745-","T133746-","G133747-","T133748-","T133749-","C133750-","C133751-","C133752-","T133753-","G133754-","G133755-","C133756-","A133757-","T133758-","T133759-","A133760-","C133761-","C133762-","G133763-","A133764-","G133765-","T133766-","T133767-","C133768-","A133769-","G133770-","T133771-","T133772-","T133773-","T133774-","A133775-","T133776-","A133777-","T133778-","G133779-","C133780-","C133781-","G133782-","A133783-","A133784-","T133785-","A133786-","G133787-","A133788-","G133789-","T133790-","T133791-","C133792-","T133793-","G133794-","A133795-","T133796-","T133797-","C133798-","A133799-","T133800-","C133801-","C133802-","T133803-","T133804-","T133805-","G133806-","A133807-","G133808-","A133809-","A133810-","G133811-","A133812-","T133813-","C133814-","T133815-","C133816-","T133817-","A133818-","G133819-","C133820-","G133821-","A133822-","T133823-","C133824-","G133825-","T133826-","T133827-","C133828-","A133829-","A133830-","G133831-","A133832-","T133833-","C133834-","C133835-","C133836-","T133837-","G133838-","A133839-","T133840-","T133841-","C133842-","T133843-","A133844-","G133845-","T133846-","C133847-","T133848-","T133849-","T133850-","A133851-","G133852-","C133853-","C133854-","T133855-","A133856-","T133857-","T133858-","T133859-","A133860-","C133861-","C133862-","T133863-","C133864-","C133865-","T133866-","C133867-","A133868-","G133869-","A133870-","A133871-","G133872-","A133873-","T133874-","G133875-","C133876-","T133877-","C133878-","C133879-","G133880-","T133881-","T133882-","A133883-","C133884-","C133885-","G133886-","T133887-","T133888-","T133889-","T133890-","T133891-","A133892-","C133893-","A133894-","A133895-","T133896-","C133897-","G133898-","T133899-","T133900-","A133901-","A133902-","G133903-","A133904-","T133905-","G133906-","T133907-","C133908-","T133909-","A133910-","T133911-","C133912-","A133913-","A133914-","G133915-","A133916-","T133917-","C133918-","C133919-","A133920-","T133921-","G133922-","A133923-","T133924-","T133925-","C133926-","T133927-","A133928-","T133929-","C133930-","T133931-","C133932-","T133933-","T133934-","T133935-","T133936-","C133937-","C133938-","A133939-","T133940-","A133941-","T133942-","C133943-","A133944-","G133945-","C134152T","G134354T","A135987T","G136015A","C136390A","-136555T","-136558G","A136864C","C137830T","T138627C","G138840T","T139429-","T139430-","G139431-","G141071A","A141497G","G141759A","G142056A","C142159T","T142338C","A142755-","G143459-","T143743G","G143831A","C144025T","G144742A","C145303T","G145642T","A145892-","G145908A","T145979-","A145980-","A145981-","C146084-","G146085-","C146395A","G146494A","G146632T","A146863-","T146864-","T146884-","T146885-","T146886-","A146887-","T146888-","A146889-","T146890-","T146891-","T146892-","T146893-","A146894-","T146895-","A146969-","C147489T","G147780A","C147800T","A148336-","T148344A","A150156G","T150539-","A150549T","A150968T","G151022-","A151023-","C151024-","A151025-","T151026-","A151043-","T151289G","A152267-","T152268-","T152269-","G152328A","G154263A","C154354-","T154355-","C154389T","T154664A","C154791A","T155424-","C155483A","G155888A","A156210-","T156371-","A156372-","C156373-","T156374-","G156375-","A156376-","C156377-","T156378-","A156379-","C156380-","A156381-","T156382-","G156383-","T156384-","A156385-","C156386-","T156387-","A156388-","T156389-","T156390-","T156391-","T156392-","A156393-","C156394-","A156395-","T156396-","T156397-","A156398-","C156399-","T156400-","A156401-","C156402-","A156403-","T156404-","T156405-","G156406-","G156407-","C156408-","T156409-","A156410-","C156411-","G156412-","G156413-","C156414-","T156416-","A156417-","T156418-","A156419-","T156420-","A156421-","C156422-","C156423-","T156424-","A156425-","C156426-","T156427-","T156428-","C156429-","G156430-","T156431-","C156432-","A156433-","C156434-","T156435-","T156436-","C156437-","C156438-","A156439-","C156440-","A156441-","C156442-","G156443-","C156444-","T156445-","C156446-","C156447-","G156448-","G156449-","T156450-","A156451-","A156452-","A156453-","C156454-","G156455-","G156456-","G156457-","T156458-","G156459-","T156460-","C156461-","A156462-","T156463-","G156464-","T156465-","G156466-","A156467-","C156468-","G156469-","A156470-","G156471-","G156472-","G156473-","A156474-","G156475-","A156476-","A156477-","T156478-","C156479-","T156480-","T156481-","G156482-","A156483-","T156484-","A156485-","A156486-","G156487-","A156488-","G156489-","G156490-","C156491-","A156492-","T156493-","A156494-","A156495-","T156496-","C156497-","A156498-","A156499-","T156500-","G156501-","T156502-","T156503-","G156504-","T156505-","A156506-","A156507-","T156508-","C156509-","C156510-","G156511-","G156512-","T156513-","G156514-","T156515-","C156516-","C156517-","A156518-","C156519-","C156520-","T156521-","G156522-","G156523-","A156524-","G156525-","A156526-","A156527-","T156528-","T156529-","T156530-","G156531-","C156532-","C156533-","A156534-","A156535-","G156536-","G156537-","T156538-","C156539-","A156540-","G156541-","A156542-","T156543-","G156544-","T156545-","A156546-","G156547-","G156549-","T156550-","T156551-","G156552-","G156553-","T156554-","A156555-","G156556-","T156557-","G156558-","A156559-","T156560-","A156561-","A156562-","C156563-","A156564-","C156565-","A156566-","A156567-","A156568-","A156569-","T156570-","G156571-","T156572-","G156573-","A156574-","A156575-","C156576-","A156577-","C156578-","T156579-","G156580-","C156581-","C156582-","C156583-","A156584-","C156585-","C156586-","T156587-","C156588-","A156589-","T156590-","A156591-","C156592-","A156593-","T156594-","A156595-","T156596-","A156597-","C156598-","C156599-","G156600-","C156601-","A156602-","A156603-","T156604-","C156605-","C156606-","C156607-","C156608-","A156609-","A156610-","T156611-","T156612-","A156613-","T156614-","T156615-","C156616-","T156617-","A156618-","A156619-","T156620-","A156621-","G156622-","A156623-","T156624-","G156625-","T156626-","C156627-","A156628-","T156629-","C156630-","A156631-","A156632-","T156633-","G156634-","T156635-","A156636-","G156637-","A156638-","A156639-","A156640-","A156641-","T156642-","G156643-","C156644-","C156645-","C156646-","A156647-","A156648-","C156649-","A156650-","G156651-","G156652-","A156653-","T156654-","C156655-","A156656-","T156657-","T156658-","T156659-","G156660-","A156661-","T156662-","A156663-","A156664-","G156665-","G156666-","T156667-","A156668-","A156669-","A156670-","G156671-","T156672-","G156673-","T156674-","A156675-","C156676-","C156677-","G156678-","G156679-","A156680-","A156681-","C156682-","A156683-","C156684-","A156685-","G156686-","A156687-","A156688-","C156689-","A156690-","A156691-","A156692-","T156693-","G156694-","T156695-","T156696-","C156697-","G156698-","T156699-","G156700-","T156701-","C156702-","A156703-","T156704-","C156705-","C156706-","T156707-","G156708-","G156709-","T156710-","T156711-","G156712-","G156713-","T156714-","A156715-","T156716-","A156717-","C156718-","G156719-","C156720-","T156721-","A156722-","C156723-","T156724-","G156725-","A156726-","T156727-","T156728-","C156729-","T156730-","T156731-","C156732-","A156733-","C156734-","A156735-","G156736-","A156737-","C156738-","T156739-","G156740-","A156741-","A156742-","G156743-","A156744-","T156745-","T156746-","G156747-","T156748-","C156749-","G156750-","A156751-","G156752-","A156753-","T156754-","T156755-","T156756-","G156757-","T156758-","G156759-","T156760-","A156761-","C156762-","C156763-","A156764-","A156765-","A156766-","A156767-","A156768-","A156769-","G156770-","G156771-","A156772-","G156773-","A156774-","T156775-","G156776-","T156777-","C156778-","C156779-","A156780-","T156781-","G156782-","C156783-","G156784-","G156785-","A156786-","T156787-","A156788-","C156789-","T156790-","T156791-","T156792-","G156793-","G156794-","T156795-","G156796-","G156797-","A156798-","A156799-","T156800-","A156801-","G156802-","A156803-","T156804-","G156805-","A156806-","A156807-","G156808-","G156809-","A156810-","A156811-","A156812-","T156813-","C156814-","C156815-","T156816-","A156817-","T156818-","T156819-","T156820-","G156821-","T156822-","A156823-","A156824-","A156825-","T156826-","C156827-","G156828-","T156829-","G156830-","T156831-","T156832-","G156833-","T156834-","G156835-","T156836-","T156837-","G156838-","G156839-","T156840-","G156841-","A156842-","A156843-","T156844-","A156845-","T156846-","T156847-","G156848-","C156849-","G156850-","A156851-","C156852-","T156853-","A156854-","C156855-","C156856-","T156857-","A156858-","C156859-","G156860-","T156861-","A156862-","A156863-","T156864-","T156865-","A156866-","T156867-","A156868-","G156869-","A156870-","C156871-","T156872-","T156873-","G156874-","A156875-","T156876-","C156877-","C156878-","A156879-","T156880-","T156881-","T156882-","C156883-","C156884-","T156885-","C156886-","C156887-","A156888-","T156889-","G156890-","C156891-","A156892-","A156893-","A156894-","C156895-","T156896-","A156897-","T156898-","C156899-","T156900-","A156901-","T156902-","C156903-","T156904-","A156905-","A156906-","A156907-","T156908-","G156909-","T156910-","A156911-","A156912-","T156913-","T156914-","A156915-","A156916-","T156917-","T156918-","A156919-","T156920-","G156921-","A156922-","T156923-","T156924-","T156925-","T156926-","G156927-","A156928-","T156929-","G156930-","A156931-","T156932-","A156933-","A156934-","T156935-","G156936-","T156937-","T156938-","A156939-","C156940-","C156941-","A156942-","T156943-","A156944-","C156945-","A156946-","T156947-","T156948-","A156949-","T156950-","A156951-","T156952-","C156953-","G156954-","C156955-","T156956-","A156957-","C156958-","T156959-","T156960-","G156961-","G156962-","T156963-","T156964-","A156965-","G156966-","T156967-","G156968-","T156969-","G156970-","T156971-","A156972-","T156973-","T156974-","A156975-","T156976-","T156977-","C156978-","A156979-","G156980-","T156981-","A156982-","T156983-","G156984-","G156985-","A156986-","A156987-","G156988-","A156989-","C156990-","C156991-","T156992-","A156993-","T156994-","T156995-","A156996-","A156997-","T156998-","A156999-","A157000-","T157001-","T157002-","A157003-","C157004-","T157005-","T157006-","A157007-","T157008-","C157009-","T157010-","T157011-","T157012-","T157013-","G157014-","A157015-","C157016-","G157017-","A157018-","T157019-","C157020-","T157021-","T157022-","G157023-","T157024-","T157025-","A157026-","T157027-","A157028-","A157029-","T157030-","T157031-","A157032-","T157033-","A157034-","A157035-","T157036-","A157037-","T157038-","A157039-","A157040-","A157041-","A157042-","A157043-","T157044-","A157045-","C157046-","T157047-","T157048-","A157049-","T157050-","G157051-","A157052-","C157053-","A157054-","T157055-","A157056-","G157057-","T157058-","A157059-","A157060-","C157061-","T157062-","C157063-","A157064-","T157065-","A157066-","A157067-","T157068-","T157069-","G157070-","C157071-","T157072-","G157073-","A157074-","C157075-","G157076-","C157077-","G157078-","A157079-","T157080-","A157081-","A157082-","A157083-","T157084-","T157085-","C157086-","G157087-","T157088-","A157089-","A157090-","T157091-","A157092-","A157093-","T157094-","C157095-","T157096-","G157097-","T157098-","T157099-","T157100-","T157101-","G157102-","T157103-","T157104-","C157105-","A157106-","A157107-","A157108-","T157109-","T157110-","T157111-","T157112-","T157113-","A157114-","T157115-","A157116-","A157117-","G157118-","G157119-","A157120-","A157121-","T157122-","C157123-","T157124-","A157125-","C157126-","A157127-","G157128-","G157129-","C157130-","A157131-","T157132-","A157133-","A157134-","A157135-","A157136-","A157137-","T157138-","A157139-","A157140-","A157141-","A157142-","A157143-","T157144-","A157145-","T157146-","A157147-","A157148-","T157149-","C157150-","T157151-","A157152-","T157153-","A157154-","A157155-","T157156-","A157157-","T157158-","A157159-","C157160-","T157161-","C157162-","T157163-","T157164-","A157165-","C157166-","A157167-","A157168-","C157169-","G157170-","C157171-","C157172-","A157173-","T157174-","C157175-","A157176-","T157177-","G157178-","A157179-","A157180-","T157181-","A157182-","G157183-","C157184-","A157185-","G157186-","T157187-","G157188-","A157189-","A157190-","T157191-","T157192-","A157193-","A157194-","T157195-","T157196-","G157197-","C157198-","T157199-","G157200-","T157201-","T157202-","A157203-","T157204-","T157205-","A157206-","T157207-","G157208-","G157209-","A157210-","T157211-","T157212-","T157213-","A157214-","G157215-","A157216-","A157217-","A157218-","T157219-","A157220-","G157221-","T157222-","G157223-","G157224-","A157225-","C157226-","G157227-","A157228-","T157229-","T157230-","T157231-","T157232-","G157233-","T157234-","G157235-","A157236-","T157237-","A157238-","T157239-","T157240-","A157241-","A157242-","T157243-","A157244-","T157245-","A157246-","G157247-","T157248-","T157249-","A157250-","T157251-","T157252-","A157253-","A157254-","T157255-","G157256-","A157257-","T157258-","G157259-","A157260-","A157261-","A157262-","G157263-","G157264-","A157265-","T157266-","A157267-","A157268-","A157269-","C157270-","G157271-","C157272-","T157273-","C157274-","A157275-","T157276-","A157277-","G157278-","A157279-","C157280-","T157281-","C157282-","A157283-","T157284-","C157285-","C157286-","T157287-","A157288-","T157289-","C157290-","T157291-","G157292-","G157293-","A157294-","G157295-","C157296-","C157297-","T157298-","C157299-","C157300-","G157301-","A157302-","A157303-","T157304-","A157305-","T157306-","T157307-","T157308-","T157309-","T157310-","T157311-","C157312-","C157313-","A157314-","T157315-","T157316-","C157317-","T157318-","G157319-","T157320-","T157321-","T157322-","T157323-","C157324-","C157325-","A157326-","A157327-","T157328-","A157329-","A157330-","T157331-","T157332-","T157333-","T157334-","A157335-","T157336-","C157337-","G157338-","A157339-","T157340-","T157341-","C157342-","T157343-","A157344-","A157345-","T157346-","G157347-","A157348-","A157349-","T157350-","A157351-","C157352-","G157353-","A157354-","A157355-","G157356-","T157357-","T157358-","A157359-","A157360-","T157361-","C157362-","T157363-","A157364-","A157365-","G157366-","T157367-","C157368-","A157369-","T157370-","T157371-","T157372-","A157373-","G157374-","A157375-","T157376-","T157377-","A157378-","T157379-","C157380-","A157381-","A157382-","A157383-","G157384-","T157385-","G157386-","T157387-","T157388-","A157389-","A157390-","C157391-","T157392-","A157393-","T157394-","T157395-","T157396-","G157397-","A157398-","T157399-","C157400-","G157401-","A157402-","T157403-","T157404-","A157405-","C157406-","A157407-","T157408-","T157409-","T157410-","A157411-","T157412-","G157413-","G157414-","G157415-","A157416-","T157417-","A157418-","C157419-","C157420-","T157421-","T157422-","T157423-","G157424-","A157425-","G157426-","C157427-","C157428-","T157429-","A157430-","A157431-","C157432-","T157433-","A157434-","A157435-","C157436-","G157437-","A157438-","T157439-","A157440-","A157441-","C157442-","G157443-","T157444-","G157445-","A157446-","A157447-","A157448-","T157449-","A157450-","T157451-","A157452-","T157453-","T157454-","C157455-","T157456-","T157457-","T157458-","C157459-","A157460-","A157461-","C157462-","C157463-","G157464-","C157465-","T157466-","G157467-","A157468-","T157469-","T157470-","T157471-","T157472-","T157473-","T157474-","T157475-","A157476-","C157477-","A157478-","A157479-","A157480-","T157481-","T157482-","G157483-","G157484-","A157485-","T157486-","C157487-","T157488-","G157489-","C157490-","C157491-","A157492-","T157493-","T157494-","A157495-","C157496-","T157497-","G157498-","A157499-","G157500-","T157501-","G157502-","C157503-","G157504-","A157505-","A157506-","A157507-","A157508-","A157509-","T157510-","A157511-","C157512-","A157513-","T157514-","A157515-","C157516-","T157517-","T157518-","A157519-","A157520-","A157521-","A157522-","A157523-","T157524-","C157525-","T157526-","T157527-","T157528-","G157529-","T157530-","T157531-","T157532-","T157533-","A157534-","G157535-","A157536-","A157537-","A157538-","C157539-","T157540-","G157541-","T157542-","A157543-","T157544-","C157545-","G157546-","A157547-","T157548-","T157549-","T157550-","C157551-","T157552-","A157553-","C157554-","A157555-","T157556-","A157557-","T157558-","A157559-","C157560-","G157561-","C157562-","T157563-","G157564-","A157565-","T157566-","A157567-","A157568-","A157569-","T157570-","A157571-","T157572-","A157573-","A157574-","T157575-","A157576-","A157577-","C157578-","A157579-","A157580-","G157581-","A157582-","A157583-","A157584-","A157585-","T157586-","A157587-","G157588-","A157589-","A157590-","T157591-","T157592-","A157593-","G157594-","C157595-","A157596-","T157597-","C157598-","G157599-","T157600-","T157601-","T157602-","A157603-","A157604-","C157605-","A157606-","C157607-","A157608-","A157609-","T157610-","A157611-","T157612-","T157613-","A157614-","C157615-","G157616-","A157617-","A157618-","A157619-","T157620-","A157621-","T157622-","T157623-","T157624-","T157625-","G157626-","A157627-","G157628-","A157629-","C157630-","T157631-","C157632-","A157633-","T157634-","C157635-","A157636-","A157637-","C157638-","A157639-","A157640-","T157641-","G157642-","A157643-","A157644-","A157645-","A157646-","C157647-","T157648-","T157649-","T157650-","A157651-","A157652-","A157653-","T157654-","A157655-","C157656-","T157657-","T157658-","A157659-","A157660-","C157661-","A157662-","G157663-","A157664-","G157665-","G157666-","A157667-","A157668-","T157669-","C157670-","A157671-","A157672-","T157673-","G157674-","A157675-","T157676-","A157677-","G157688-","C157689-","G157690-","G157693-","T157697-","G157698-","T157699-","T157700-","A157701-","T157702-","A157703-","T157704-","A157705-","T157706-","A157707-","A157708-","A157709-","A157710-","A157711-","A157712-","T157713-","G157714-","A157715-","G157716-","G157717-","A157718-","T157719-","T157720-","T157721-","C157722-","A157723-","C157724-","C157725-","C157726-","C157727-","A157728-","C157729-","T157730-","G157731-","A157732-","T157733-","T157734-","C157735-","T157736-","C157737-","A157738-","T157739-","T157740-","A157741-","A157742-","A157743-","T157744-","G157745-","G157746-","T157747-","T157748-","A157749-","G157750-","A157751-","G157752-","A157753-","G157754-","T157755-","A157756-","C157757-","A157758-","C157759-","C157760-","A157761-","A157762-","C157763-","C157764-","A157765-","T157766-","G157767-","T157768-","A157769-","C157770-","C157771-","G157772-","T157773-","C157774-","G157775-","A157776-","G157777-","T157778-","T157779-","A157780-","C157781-","T157782-","T157783-","A157784-","G157785-","A157786-","T157787-","G157788-","C157789-","C157790-","T157791-","C157792-","A157793-","G157794-","A157795-","A157796-","T157797-","A157798-","T157799-","C157800-","A157801-","T157802-","T157803-","T157804-","C157805-","T157806-","T157807-","T157808-","C157809-","C157810-","C157811-","C157812-","A157813-","C157814-","A157815-","A157816-","G157817-","T157818-","T157819-","A157820-","T157821-","A157822-","A157823-","A157824-","A157825-","T157826-","C157827-","A157828-","C157829-","T157830-","T157831-","T157832-","A157833-","T157834-","A157835-","G157836-","T157837-","C157838-","A157839-","T157840-","C157841-","G157842-","A157843-","C157844-","T157845-","G157846-","G157847-","T157848-","T157849-","A157850-","G157851-","T157852-","T157853-","C157854-","A157855-","A157856-","T157857-","C157858-","T157859-","A157860-","C157861-","G157862-","A157863-","A157864-","T157865-","G157866-","T157867-","A157868-","T157869-","A157870-","A157871-","C157872-","A157873-","T157874-","T157875-","C157876-","T157877-","T157878-","A157879-","A157880-","A157881-","C157882-","A157883-","A157884-","T157885-","A157886-","T157887-","A157888-","G157889-","C157890-","A157891-","T157892-","T157893-","C157894-","T157895-","T157896-","G157897-","G157898-","A157899-","T157900-","A157901-","A157902-","A157903-","T157904-","C157905-","A157906-","T157907-","T157908-","T157909-","C157910-","C157911-","T157912-","A157913-","G157914-","A157915-","T157916-","A157917-","C157918-","C157919-","A157920-","T157921-","A157922-","T157923-","C157924-","A157925-","T157926-","C157927-","G157928-","A157929-","G157930-","T157931-","T157932-","G157933-","A157934-","T157935-","A157936-","T157937-","C157938-","T157939-","A157940-","T157941-","C157942-","G157943-","G157944-","T157945-","A157946-","T157947-","A157948-","A157949-","G157950-","T157951-","A157952-","A157953-","T157954-","T157955-","C157956-","A157957-","C157958-","A157959-","T157960-","G157961-","A157962-","T157963-","A157964-","A157965-","G157966-","A157967-","T157968-","T157969-","T157970-","C157971-","C157972-","A157973-","T157974-","A157975-","A157976-","A157977-","C157978-","T157979-","G157980-","C157981-","T157982-","A157983-","C157984-","A157985-","A157986-","T157987-","C157988-","A157989-","T157990-","A157991-","A157992-","A157993-","A157994-","A157995-","A157996-","A157997-","T157998-","T157999-","C158000-","A158001-","T158002-","G158003-","G158004-","G158005-","A158006-","A158007-","A158008-","T158009-","G158010-","A158011-","T158012-","A158013-","T158014-","C158015-","T158016-","T158017-","C158018-","A158019-","C158020-","G158021-","T158022-","A158023-","G158024-","A158025-","T158026-","G158030-","G158031-","T158032-","G158033-","T158034-","A158035-","G158036-","T158037-","T158038-","T158039-","C158040-","G158041-","C158042-","A158043-","G158044-","T158045-","G158046-","A158047-","C158048-","C158049-","G158050-","T158051-","C158052-","C158053-","T158054-","G158055-","G158056-","A158057-","T158058-","A158059-","A158060-","T158061-","A158062-","T158063-","T158064-","A158065-","T158066-","C158067-","T158068-","A158069-","T158070-","A158071-","T158072-","G158073-","A158074-","T158075-","G158076-","G158077-","G158078-","T158079-","G158080-","G158081-","A158082-","T158083-","A158084-","T158085-","G158086-","A158087-","T158088-","C158089-","A158090-","G158091-","T158092-","C158093-","C158094-","C158095-","T158096-","G158097-","T158098-","A158099-","T158100-","A158101-","G158102-","A158103-","A158104-","G158105-","T158106-","T158107-","C158108-","A158109-","A158110-","A158111-","G158112-","G158113-","T158114-","T158115-","A158116-","T158117-","A158118-","G158119-","C158120-","G158121-","T158122-","A158123-","C158124-","A158125-","A158126-","T158127-","A158128-","C158129-","A158130-","T158131-","G158132-","T158133-","A158134-","C158135-","T158136-","A158137-","A158138-","T158139-","T158140-","C158141-","T158142-","T158143-","G158144-","G158145-","A158146-","T158147-","A158148-","T158149-","A158150-","T158151-","G158152-","A158153-","T158154-","A158155-","T158156-","A158157-","C158158-","C158159-","A158160-","G158161-","A158162-","G158163-","C158164-","T158165-","A158166-","A158167-","A158168-","A158169-","T158171-","A158172-","T158173-","C158174-","C158175-","T158176-","C158177-","G158178-","T158179-","T158180-","C158181-","T158182-","A158183-","A158184-","T158185-","T158186-","G158187-","C158188-","G158189-","G158190-","A158191-","G158192-","G158193-","A158194-","G158195-","T158196-","T158197-","G158198-","C158199-","C158200-","A158201-","A158202-","T158203-","G158204-","A158205-","C158206-","G158207-","A158208-","A158209-","T158210-","A158211-","C158212-","A158213-","T158214-","T158215-","T158216-","A158217-","T158218-","T158219-","G158220-","T158221-","A158222-","T158223-","A158224-","G158225-","G158226-","C158227-","G158228-","G158229-","T158230-","A158231-","T158232-","A158233-","C158234-","G158235-","C158236-","G158237-","A158238-","T158239-","C158240-","A158241-","G158242-","G158243-","A158244-","G158245-","T158246-","C158247-","A158248-","T158249-","C158250-","G158251-","T158252-","T158253-","G158254-","A158255-","T158256-","A158257-","T158258-","C158259-","T158260-","A158261-","G158262-","T158263-","A158264-","T158265-","C158266-","G158267-","A158268-","T158269-","A158270-","G158271-","A158272-","T158273-","G158274-","G158275-","A158276-","A158277-","G158278-","C158279-","C158280-","A158281-","T158282-","C158283-","A158284-","A158285-","A158286-","A158287-","C158288-","C158289-","A158290-","T158291-","A158292-","T158293-","T158294-","G158295-","G158296-","C158297-","A158298-","G158299-","A158300-","A158301-","G158302-","T158303-","A158304-","T158305-","G158306-","C158307-","T158308-","A158309-","A158310-","A158311-","A158312-","T158313-","G158314-","T158315-","G158316-","C158317-","G158318-","A158319-","A158320-","C158321-","C158322-","A158323-","A158324-","A158325-","A158326-","T158327-","G158328-","T158329-","G158330-","A158331-","T158332-","A158333-","T158334-","G158335-","G158336-","G158337-","G158338-","T158339-","T158340-","G158341-","C158342-","G158343-","A158344-","T158345-","T158346-","T158347-","T158348-","A158349-","A158350-","A158351-","C158352-","G158353-","G158354-","A158355-","T158356-","T158357-","A158358-","A158359-","T158360-","A158361-","T158362-","A158363-","T158364-","G158365-","T158366-","C158367-","A158368-","T158369-","A158370-","G158371-","G158372-","T158373-","G158374-","G158375-","A158376-","G158377-","T158378-","C158379-","G158380-","T158381-","T158382-","A158383-","A158384-","A158385-","G158386-","G158387-","T158388-","G158389-","A158390-","C158391-","A158392-","C158393-","A158394-","C158395-","A158396-","T158397-","G158398-","T158399-","A158400-","C158401-","C158402-","G158403-","A158404-","C158405-","G158406-","C158407-","A158408-","C158409-","T158410-","A158411-","G158412-","A158413-","G158414-","A158415-","G158416-","T158417-","T158418-","T158419-","A158420-","T158421-","C158422-","A158423-","G158424-","A158425-","A158426-","G158427-","A158428-","T158429-","G158430-","G158431-","A158432-","T158433-","G158434-","G158435-","A158436-","T158437-","G158438-","A158439-","A158440-","T158441-","C158442-","A158443-","T158444-","C158445-","A158446-","A158447-","C158448-","G158449-","T158450-","C158451-","T158452-","T158453-","C158454-","C158455-","A158456-","A158457-","T158458-","A158459-","A158460-","A158461-","A158462-","A158463-","T158464-","G158465-","T158466-","C158467-","C158468-","A158469-","A158470-","T158471-","A158472-","T158473-","G158474-","T158475-","C158476-","G158477-","A158478-","C158479-","G158480-","A158481-","T158482-","T158483-","G158484-","T158485-","T158486-","C158487-","A158488-","T158489-","G158490-","C158491-","T158492-","G158493-","G158494-","A158495-","A158496-","A158497-","G158498-","A158499-","T158500-","T158501-","T158502-","A158503-","T158504-","A158505-","T158506-","A158507-","T158508-","C158509-","T158510-","G158511-","G158512-","A158513-","G158514-","G158515-","T158516-","T158517-","A158518-","C158519-","A158520-","A158521-","C158522-","A158523-","A158524-","T158525-","A158526-","G158527-","T158528-","A158529-","G158530-","T158531-","G158532-","T158533-","A158534-","G158535-","T158536-","T158537-","A158538-","A158539-","T158540-","G158541-","T158542-","A158543-","A158544-","T158545-","A158546-","T158547-","C158548-","G158549-","A158550-","A158551-","T158552-","C158553-","T158554-","A158555-","G158556-","T158557-","C158558-","C158559-","T158560-","T158561-","A158562-","G158563-","C158564-","T158565-","A158566-","T158567-","A158568-","A158569-","T158570-","C158571-","C158572-","G158573-","A158574-","T158575-","A158576-","T158577-","A158578-","T158579-","G158580-","A158581-","T158582-","G158583-","A158584-","A158585-","T158586-","G158587-","G158588-","A158589-","C158590-","C158591-","A158592-","A158593-","A158594-","T158595-","T158596-","A158597-","T158598-","C158599-","A158600-","T158601-","C158602-","A158603-","T158604-","T158605-","A158606-","A158607-","A158608-","T158609-","A158610-","T158611-","T158612-","C158613-","C158614-","T158615-","A158616-","G158617-","A158618-","A158619-","T158620-","T158621-","A158622-","A158623-","T158624-","C158625-","C158626-","T158627-","G158628-","C158629-","T158630-","C158631-","T158632-","A158633-","T158634-","T158751G","G160043-","C160057A","A160270G","C161356T","A161579G","T161591C","T162384C","G162388A","C162447T","T162852A","A163207-","A163208-","C163209-","T163210-","A163211-","A163212-","C163213-","T163214-","C163256T","A163886G","G164849A","C166006T","C166196T","C166309A","T166712-","G167029A","C168226T","C168466A","C169125T","G169672A","A169723-","A169725-","T169726-","T169792-","G170918-","C170999T","T172063-","A172550G","C172644T","C172671T","G173363T","G173436A","C173474T","A174044T","C174102A","C174146T","G174183T","G174537-","A174538-","T174539-","G174540-","A174541-","A174542-","T174855C","G177853A","A178328-","C178702T","C179366T","A180163G","T180435A","A180548G","C180578T","C181117-","C181118-","T181233C","C181351T","C181648A","A181790G","G181872A","A182356T","T182899C","C183555-","T183556-","A183557-","T184979C","C186840T","-187080T","G187145A","T187207-","C187533A","T187775-","G187896T","A188871G","C189206T","C189609T","A189896G","A190198-","C190199-","A190402-","T191134C","A192435-","A192436-","G192437-","T192438-","C192439-","A192440-","T192441-","A192442-","A192443-","G192444-","T192445-","T192446-","A192447-","G192448-","T192449-","T192450-","A192451-","A192452-","G192453-","T192454-","C192455-","A192456-","T192457-","A192458-","A192459-","G192460-","T192461-","T192462-","A192463-","G192464-","T192465-","T192466-","A192467-","A192468-","G192469-","T192470-","A192472-","T192473-","A192474-","A192475-","G192476-","T192477-","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-","A192490-","A192491-","G192492-","T192493-","T192494-","A192495-","G192496-","T192497-","T192498-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","G192517-","C193168T","G194067A","G194551A","A194656G","G194969-","T194970-","C194971-","T195901C","C196461T","G196580T","A196608-","A196609-","A196610-","A196611-","A196612-","A196613-","A196614-","C196735T","A197082G"],"OPG002":["V172-"],"OPG002_dup":["V172-"],"OPG003":["A189V","D489N"],"OPG005":["S3F"],"OPG021":["S219L"],"OPG023":["M109I","S258L","C304R","A426T","L602I"],"OPG027":["I47V","V126I"],"OPG029":["D153-","D154-"],"OPG031":["T80M","C241Y","G258-"],"OPG037":["C144Y"],"OPG039":["C279Y"],"OPG044":["V63A","T109A"],"OPG065":["A17T","H61N"],"OPG068":["P251S"],"OPG070":["H205Y"],"OPG072":["V10I"],"OPG076":["S20N"],"OPG080":["L521P","P582H"],"OPG085":["S79T"],"OPG089":["D303E"],"OPG091":["V62I","S73N"],"OPG092":["I244N"],"OPG108":["T111I"],"OPG109":["R364S","A630T"],"OPG113":["V537I"],"OPG117":["D454N"],"OPG120":["A19T"],"OPG123":["I172T","A313T","C436Y"],"OPG125":["E111D"],"OPG130":["A63V","L270I"],"OPG133":["F594S"],"OPG134":["E226D"],"OPG136":["A229T","D267N","F283Y"],"OPG144":["T184I"],"OPG145":["I249V"],"OPG151":["D6V","N282D"],"OPG154":["R74H"],"OPG156":["I261M"],"OPG157":["Q61-"],"OPG160":["P2S"],"OPG163":["V46A"],"OPG164":["V228-"],"OPG165":["D106N"],"OPG172":["A125V"],"OPG180":["L555-"],"OPG181":["L85M","S127Y"],"OPG188":["V265I","S419R"],"OPG189":["K185R","R506H"],"OPG191":["P50Q"],"OPG192":["G100E"],"OPG197":["M1I"],"OPG200":["E134G"],"OPG205":["R733Q"],"OPG208":["A34V","T300A"],"OPG209":["I11V","L21F"],"OPG210":["A98D","V173I","N334I","V515A","L734-"]},"labels":{"aa":"OPG002: V172-; OPG002_dup: V172-; OPG003: A189V, D489N; OPG005: S3F; OPG021: S219L; OPG023: M109I, S258L, C304R, A426T, L602I; OPG027: I47V, V126I; OPG029: D153-, D154-; OPG031: T80M, C241Y, G258-; OPG037: C144Y; OPG039: C279Y; OPG044: V63A, T109A; OPG065: A17T, H61N; OPG068: P251S; OPG070: H205Y; OPG072: V10I; OPG076: S20N; OPG080: L521P, P582H; OPG085: S79T; OPG089: D303E; OPG091: V62I, S73N; OPG092: I244N; OPG108: T111I; OPG109: R364S, A630T; OPG113: V537I; OPG117: D454N; OPG120: A19T; OPG123: I172T, A313T, C436Y; OPG125: E111D; OPG130: A63V, L270I; OPG133: F594S; OPG134: E226D; OPG136: A229T, D267N, F283Y; OPG144: T184I; OPG145: I249V; OPG151: D6V, N282D; OPG154: R74H; OPG156: I261M; OPG157: Q61-; OPG160: P2S; OPG163: V46A; OPG164: V228-; OPG165: D106N; OPG172: A125V; OPG180: L555-; OPG181: L85M, S127Y; OPG188: V265I, S419R; OPG189: K185R, R506H; OPG191: P50Q; OPG192: G100E; OPG197: M1I; OPG200: E134G; OPG205: R733Q; OPG208: A34V, T300A; OPG209: I11V, L21F; OPG210: A98D, V173I, N334I, V515A, L734-","clade":"clade I"}},"children":[{"name":"JX878417","node_attrs":{"div":301,"accession":"JX878417","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0104"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-12-14"},"strain_display":{"value":"Democratic Republic of the Congo/JX878417/2006-12-14"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T622-","C6615-","C13298T","A13302-","C13303-","C13304-","G13307-","A13308-","A13312T","A13313T","G13314T","C13316T","T13317A","G16147A","G23664T","T29805C","G31718A","C39731T","G47297T","C47929T","A49211G","C55169-","G59736A","A59910G","T70366C","T70958G","A71178-","C73040T","G87098T","C91509T","G91737A","C110159A","G117146A","G122405A","A142313G","C143414T","G143417C","T143419A","C143420-","A143421-","T143422-","G143423-","A143424-","A143425-","C143426-","C146214T","C148324A","T151060C","C159159T","C168295T","C169722-","G169724-","C169758T","A169777-","G169778-","A169779-","A169780-","G169781-","A169782-","T169783-","A169784-","T169785-","C169786-","A169787-","T169788-","G169789-","A169790-","A169791-","G169793-","A169794-","A169795-","A169796-","A172087T","C175361T","C178926-","A178927-","C179289T","T180737A","G181232A","G189594A","G191870A","A192420-","T197076G"],"OPG015_dup":["A273T"],"OPG039":["P152Q"],"OPG047":["I464V"],"OPG074":["V653-"],"OPG089":["S365A"],"OPG109":["R784S"],"OPG112":["A88V"],"OPG113":["A3T"],"OPG143":["A304V"],"OPG163":["N38D"],"OPG164":["Q213*","D214Q","H215-","E216-","H217-"],"OPG170":["G189R"],"OPG197":["T18-","D19-","T30I","E37-","D38-","I39-","M40-","N41-","E42-","I43-"],"OPG204":["T277M"],"OPG209":["S74T"]},"labels":{"aa":"OPG015_dup: A273T; OPG039: P152Q; OPG047: I464V; OPG074: V653-; OPG089: S365A; OPG109: R784S; OPG112: A88V; OPG113: A3T; OPG143: A304V; OPG163: N38D; OPG164: Q213*, D214Q, H215-, E216-, H217-; OPG170: G189R; OPG197: T18-, D19-, T30I, E37-, D38-, I39-, M40-, N41-, E42-, I43-; OPG204: T277M; OPG209: S74T"}}},{"name":"NODE_0000003","node_attrs":{"div":266,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["A204C","G994A","G16141T","C72111T","-169792C","A179227-","G186944T","G188824A","C196216T","T197006G"],"OPG027":["F79L"],"OPG210":["E1863D"]},"labels":{"aa":"OPG027: F79L; OPG210: E1863D"}},"children":[{"name":"NODE_0000004","node_attrs":{"div":272,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G1861A","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A6226-","T6227-","T6228-","C6229-","T6230-","T6281-","T6937-","G94890A","G105321T","C118612T","C121306T","A136543-","T136544-","C136545-","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","A144618G","-148336T","-173295T","-173296A","-173297T","-173298A","-173299T","-173300A","-173301T","-173302A","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T187042-","C195349T"],"OPG136":["A326T"],"OPG153":["I370D"]},"labels":{"aa":"OPG136: A326T; OPG153: I370D"}},"children":[{"name":"KJ642618","node_attrs":{"div":304,"accession":"KJ642618","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"Cameroon"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"KJ642618"},"date":{"value":"1990-XX-XX"},"strain_display":{"value":"Cameroon/KJ642618/1990-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G2075A","A4350-","G4351-","A4352-","T4353-","G4354-","G4355-","A4356-","T4357-","T4358-","A4359-","A4360-","A4361-","T4362-","C4363-","G4364-","T4365-","G4366-","T4367-","A4368-","T4369-","T4370-","C4371-","A4372-","T4373-","C4374-","G4375-","T4376-","A4377-","T4378-","A4379-","G4380-","C4381-","A4382-","A4383-","T4384-","G4385-","T4386-","A4387-","A4388-","T4389-","G4390-","G4391-","A4392-","G4393-","A4394-","G4395-","T4396-","T4397-","A4398-","C4399-","C4400-","A4401-","C4402-","A4403-","T4404-","T4405-","T4406-","T4407-","A4408-","G4409-","T4410-","C4411-","G4412-","T4413-","T4414-","T4415-","A4416-","T4417-","T4418-","C4419-","A4420-","G4421-","A4422-","T4423-","C4424-","G4425-","C4426-","A4427-","G4428-","T4429-","G4430-","T4431-","T4432-","T4433-","A4434-","A4435-","T4436-","A4437-","A4438-","C4439-","T4440-","A4441-","A4442-","T4443-","T4444-","T4445-","A4446-","A4447-","A4448-","C4449-","A4450-","G4451-","A4452-","T4453-","G4454-","A4455-","G4456-","A4457-","T4458-","G4459-","A4460-","T4461-","A4462-","T4463-","A4464-","T4465-","C4466-","C4467-","A4468-","C4469-","A4470-","T4471-","C4472-","A4473-","A4474-","A4475-","G4476-","A4477-","A4478-","T4479-","G4480-","C4481-","G4482-","A4483-","G4484-","A4485-","T4486-","A4487-","C4488-","A4489-","T4490-","A4491-","T4492-","G4493-","A4494-","C4495-","A4496-","G4497-","A4498-","C4499-","A4500-","T4501-","T4502-","A4503-","T4504-","T4505-","G4506-","A4507-","C4508-","A4509-","G4510-","A4511-","A4512-","A4513-","T4514-","G4515-","T4516-","G4517-","A4518-","C4519-","C4520-","T4521-","T4522-","C4523-","A4524-","T4525-","T4526-","A4527-","T4528-","C4529-","A4530-","C4531-","C4532-","G4533-","T4534-","C4535-","G4536-","T4537-","C4538-","C4539-","A4540-","T4541-","A4542-","A4543-","A4544-","T4545-","G4546-","C4547-","G4548-","T4549-","T4550-","A4551-","G4552-","G4553-","T4554-","A4555-","C4556-","G4557-","T4558-","A4559-","C4560-","C4561-","A4562-","C4563-","A4564-","T4565-","A4566-","C4567-","T4568-","A4569-","T4570-","C4571-","G4572-","T4573-","T4574-","A4575-","A4576-","C4577-","G4578-","A4579-","T4580-","G4581-","C4582-","G4583-","C4584-","A4585-","C4586-","A4587-","A4588-","T4589-","C4590-","T4591-","C4592-","G4593-","T4594-","C4595-","C4596-","A4597-","T4598-","T4599-","T4600-","C4601-","A4602-","T4603-","C4604-","C4605-","A4606-","T4607-","C4608-","T4609-","T4610-","C4611-","A4612-","T4613-","A4614-","A4615-","T4616-","G4617-","A4618-","T4619-","T4620-","T4621-","A4622-","C4623-","T4624-","T4625-","T4626-","T4627-","T4628-","C4629-","A4630-","T4631-","A4632-","A4633-","T4634-","T4635-","A4636-","G4637-","A4638-","G4639-","A4640-","A4641-","A4642-","A4643-","A4644-","G4645-","A4646-","T4647-","C4648-","A4649-","A4650-","G4651-","G4652-","T4653-","A4654-","T4655-","A4656-","A4657-","A4658-","A4659-","A4660-","T4661-","T4662-","A4663-","G4664-","A4665-","A4666-","G4667-","T4668-","G4669-","T4670-","T4671-","A4672-","G4673-","A4674-","C4675-","T4676-","A4677-","T4678-","A4679-","A4680-","A4681-","C4682-","T4683-","A4684-","A4685-","C4686-","T4687-","T4688-","A4689-","T4690-","A4691-","A4692-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","A4807-","T4808-","T4809-","A4810-","A4811-","C4812-","T4813-","C4814-","A4815-","T4816-","T4817-","T4818-","C4819-","A4820-","A4821-","G4822-","A4823-","A4824-","A4825-","G4826-","G4827-","T4828-","G4829-","G4830-","G4831-","T4832-","G4833-","G4834-","A4835-","G4836-","A4837-","G4838-","A4839-","A4840-","C4841-","T4842-","C4843-","T4844-","A4845-","T4846-","A4847-","T4848-","G4849-","A4850-","C4851-","A4852-","G4853-","C4854-","T4855-","T4856-","G4857-","T4858-","G4859-","A4860-","A4861-","A4862-","C4863-","A4864-","A4865-","T4866-","T4867-","A4868-","G4869-","A4870-","T4871-","C4872-","C4873-","C4874-","T4875-","A4876-","A4877-","T4878-","T4879-","T4880-","C4881-","T4882-","A4883-","A4884-","T4885-","G4886-","G4887-","A4888-","A4889-","G4890-","T4891-","T4892-","T4893-","T4894-","G4895-","A4896-","T4897-","A4898-","G4899-","G4900-","A4901-","G4902-","A4903-","T4904-","T4905-","G4906-","T4907-","C4908-","A4909-","T4910-","C4911-","A4912-","G4913-","T4914-","T4915-","G4916-","A4917-","T4918-","A4919-","C4920-","A4921-","T4922-","T4923-","G4924-","T4925-","T4926-","T4927-","A4928-","T4929-","T4930-","A4931-","T4932-","C4933-","T4934-","C4935-","A4936-","T4937-","C4938-","T4939-","A4940-","T4941-","T4942-","A4943-","G4944-","A4945-","G4946-","C4947-","A4948-","C4949-","G4950-","T4951-","C4952-","T4953-","G4954-","T4955-","T4956-","T4957-","A4958-","G4959-","A4960-","G4961-","C4962-","T4963-","T4964-","T4965-","A4966-","G4967-","T4968-","G4969-","A4970-","C4971-","C4972-","T4973-","G4974-","C4975-","T4976-","C4977-","G4978-","G4979-","T4980-","T4981-","A4982-","C4983-","T4984-","T4985-","C4986-","T4987-","G4988-","T4989-","G4990-","T4991-","A4992-","A4993-","A4994-","T4995-","C4996-","T4997-","T4998-","G4999-","A5000-","A5001-","T5002-","C5003-","C5004-","T5005-","T5006-","T5007-","A5008-","G5009-","T5010-","G5011-","A5012-","T5013-","A5014-","C5015-","A5016-","C5017-","T5018-","G5019-","T5020-","G5021-","T5022-","C5023-","A5024-","A5025-","A5026-","A5027-","C5028-","T5029-","G5030-","G5031-","A5032-","T5033-","G5034-","T5035-","T5036-","T5037-","A5038-","G5039-","A5040-","A5041-","T5042-","A5043-","C5044-","C5045-","T5046-","A5047-","T5048-","G5049-","T5050-","A5051-","G5052-","A5053-","A5054-","T5055-","A5056-","T5057-","G5058-","G5059-","G5060-","A5061-","A5062-","G5063-","C5064-","A5065-","T5066-","G5067-","C5068-","T5069-","T5070-","G5071-","T5072-","T5073-","T5074-","T5075-","T5076-","G5077-","T5078-","C5079-","T5080-","C5081-","T5082-","A5083-","T5084-","T5085-","A5086-","T5087-","A5088-","G5089-","A5090-","T5091-","T5092-","A5093-","A5094-","C5095-","T5096-","C5097-","A5098-","T5099-","A5100-","C5101-","A5102-","T5103-","G5104-","G5105-","T5106-","T5107-","G5108-","T5109-","A5110-","T5111-","T5112-","A5113-","T5114-","G5115-","A5116-","A5117-","T5118-","T5119-","T5120-","T5121-","C5122-","A5123-","T5124-","C5125-","T5126-","G5127-","C5128-","C5129-","T5130-","A5131-","A5132-","T5133-","G5134-","T5135-","A5136-","C5137-","T5138-","C5139-","C5140-","A5141-","A5142-","T5143-","T5144-","C5145-","T5146-","T5147-","G5148-","T5149-","T5150-","T5151-","A5152-","C5153-","A5154-","A5155-","T5156-","C5157-","A5158-","A5159-","T5160-","T5161-","A5162-","T5163-","A5164-","T5165-","A5166-","A5167-","T5168-","C5169-","A5170-","A5171-","A5172-","G5173-","A5174-","G5175-","T5176-","G5177-","A5178-","T5179-","G5180-","A5181-","T5182-","G5183-","C5184-","A5185-","T5186-","A5187-","C5188-","A5189-","C5190-","A5191-","T5192-","T5193-","A5194-","C5195-","A5196-","A5197-","A5198-","G5199-","T5200-","G5201-","A5202-","A5203-","T5204-","A5205-","A5206-","T5207-","C5208-","T5209-","A5210-","C5211-","C5212-","A5213-","T5214-","C5215-","A5216-","T5217-","A5218-","A5219-","A5220-","A5221-","T5222-","A5223-","C5224-","T5225-","T5226-","G5227-","A5228-","T5229-","A5230-","C5231-","A5232-","G5233-","A5234-","G5235-","C5236-","T5237-","T5238-","T5239-","A5240-","T5241-","C5242-","A5243-","C5244-","A5245-","T5246-","C5247-","A5248-","T5249-","G5250-","G5251-","T5252-","T5253-","T5254-","T5255-","C5256-","A5257-","A5258-","T5259-","T5260-","G5261-","T5262-","A5263-","T5264-","T5265-","A5266-","T5267-","T5268-","A5269-","A5270-","G5271-","T5272-","A5273-","T5274-","A5275-","G5276-","C5277-","T5278-","A5279-","A5280-","T5281-","T5282-","T5283-","T5284-","A5285-","T5286-","A5287-","C5288-","A5289-","G5290-","T5291-","C5292-","A5293-","A5294-","T5295-","A5296-","G5297-","A5298-","C5299-","A5300-","A5301-","T5302-","G5303-","G5304-","T5305-","T5306-","C5307-","T5308-","C5309-","T5310-","A5311-","A5312-","G5313-","C5314-","A5315-","A5316-","T5317-","A5318-","T5319-","T5320-","T5321-","C5322-","T5323-","A5324-","A5325-","T5326-","A5327-","T5328-","T5329-","T5330-","T5331-","A5332-","A5333-","G5334-","A5335-","T5336-","G5337-","T5338-","G5339-","C5340-","T5341-","T5342-","C5343-","C5344-","C5345-","T5346-","A5347-","C5348-","G5349-","G5350-","G5351-","C5352-","G5353-","A5354-","T5355-","G5356-","A5357-","C5358-","A5359-","G5360-","A5361-","T5362-","C5363-","C5364-","C5365-","C5366-","T5367-","A5368-","T5369-","C5370-","C5371-","A5372-","C5373-","G5374-","G5375-","C5376-","C5377-","A5378-","C5379-","G5380-","T5381-","C5382-","A5383-","A5384-","G5385-","A5386-","C5387-","A5388-","T5389-","G5390-","T5391-","A5392-","T5393-","A5394-","T5395-","C5396-","C5397-","A5398-","T5399-","T5400-","A5401-","C5402-","T5403-","C5404-","A5405-","T5406-","T5407-","A5408-","C5409-","T5410-","G5411-","C5412-","G5413-","T5414-","T5415-","G5416-","A5417-","C5418-","A5419-","T5420-","T5421-","T5422-","G5423-","C5424-","T5425-","C5426-","C5427-","A5428-","T5429-","T5430-","T5431-","T5432-","C5433-","T5434-","A5435-","A5436-","T5437-","A5438-","G5439-","C5440-","C5441-","A5442-","T5443-","G5444-","A5445-","T5446-","A5447-","C5448-","T5449-","A5450-","A5451-","A5452-","T5453-","C5454-","T5455-","A5456-","T5457-","A5458-","T5459-","A5460-","A5461-","C5462-","C5463-","T5464-","G5465-","C5466-","A5467-","T5468-","A5469-","G5470-","A5471-","T5472-","A5473-","G5474-","C5475-","G5476-","C5477-","G5478-","A5479-","T5480-","A5481-","A5482-","A5483-","G5484-","C5485-","A5486-","A5487-","G5488-","G5489-","T5490-","C5491-","C5492-","T5493-","T5494-","C5495-","C5496-","A5497-","C5498-","C5499-","A5500-","G5501-","C5502-","A5503-","T5504-","C5505-","T5506-","A5507-","G5508-","T5509-","T5510-","G5511-","A5512-","T5513-","T5514-","G5515-","A5516-","T5517-","A5518-","T5519-","C5520-","T5521-","T5522-","C5523-","A5524-","A5525-","T5526-","A5527-","T5528-","A5529-","T5530-","G5531-","G5532-","G5533-","A5534-","T5535-","A5536-","C5537-","A5538-","A5539-","A5540-","G5541-","C5542-","T5543-","T5544-","A5545-","T5546-","A5547-","A5548-","A5549-","T5550-","T5551-","T5552-","C5553-","T5554-","A5555-","A5556-","T5557-","A5558-","C5559-","T5560-","G5561-","T5562-","G5563-","G5564-","G5565-","T5566-","T5567-","C5568-","A5569-","T5570-","C5571-","T5572-","A5573-","C5574-","A5575-","A5576-","G5577-","G5578-","A5579-","A5580-","T5581-","C5582-","C5583-","C5584-","C5585-","T5586-","A5587-","G5588-","T5589-","A5590-","T5591-","A5592-","C5593-","T5594-","G5595-","A5596-","A5597-","T5598-","T5599-","A5600-","T5601-","T5602-","T5603-","T5604-","A5605-","T5606-","A5607-","T5608-","A5609-","G5610-","A5611-","T5612-","C5613-","T5614-","A5615-","A5616-","T5617-","T5618-","T5619-","A5620-","A5621-","C5622-","A5623-","T5624-","C5625-","A5626-","T5627-","T5628-","T5629-","T5630-","C5631-","A5632-","T5633-","C5634-","T5635-","G5636-","G5637-","G5638-","A5639-","T5640-","A5641-","C5642-","C5643-","A5644-","C5645-","A5646-","A5647-","T5648-","T5649-","C5650-","A5651-","A5652-","A5653-","A5654-","T5655-","A5656-","A5657-","A5658-","C5659-","T5660-","C5661-","A5662-","A5663-","C5664-","A5665-","A5666-","C5667-","A5668-","C5669-","T5670-","A5671-","C5672-","T5673-","T5674-","T5675-","C5676-","C5677-","T5678-","T5679-","T5680-","T5681-","T5682-","A5683-","C5684-","A5685-","T5686-","A5687-","T5688-","T5689-","C5690-","C5691-","C5692-","C5693-","T5694-","A5695-","A5696-","A5697-","A5698-","T5699-","A5700-","G5701-","G5702-","C5703-","A5704-","T5705-","T5706-","C5707-","A5708-","A5709-","G5710-","C5711-","A5712-","T5713-","T5714-","C5715-","T5716-","A5717-","T5718-","T5719-","T5720-","T5721-","A5722-","T5723-","A5724-","T5725-","A5726-","T5727-","T5728-","A5729-","C5730-","A5731-","G5732-","C5733-","C5734-","C5735-","C5736-","A5737-","T5738-","G5739-","A5740-","T5741-","C5742-","T5743-","A5744-","C5745-","C5746-","A5747-","T5748-","A5749-","A5750-","A5751-","A5752-","T5753-","C5754-","A5755-","A5756-","C5757-","A5758-","A5759-","T5760-","G5761-","T5762-","C5763-","T5764-","A5765-","T5766-","T5767-","T5768-","C5769-","T5770-","A5771-","C5772-","A5773-","T5774-","A5775-","T5776-","G5777-","C5778-","A5779-","T5780-","T5781-","A5782-","G5783-","A5784-","T5785-","A5786-","G5787-","A5788-","T5789-","A5790-","G5791-","T5792-","A5793-","A5794-","A5795-","G5796-","T5797-","A5798-","A5799-","G5800-","A5801-","G5802-","A5803-","T5804-","C5805-","T5806-","T5807-","G5808-","T5809-","A5810-","C5811-","A5812-","G5813-","A5814-","A5815-","T5816-","T5817-","A5818-","C5819-","A5820-","A5821-","T5822-","T5823-","C5824-","T5825-","T5826-","A5827-","A5828-","T5829-","A5830-","A5831-","T5832-","T5833-","A5834-","T5835-","A5836-","G5837-","A5838-","G5839-","A5840-","A5841-","A5842-","A5843-","T5844-","A5845-","T5846-","C5847-","T5848-","T5849-","C5850-","C5851-","A5852-","T5853-","A5854-","T5855-","A5856-","A5857-","T5858-","T5859-","C5860-","T5861-","T5862-","T5863-","G5864-","A5865-","C5866-","A5867-","C5868-","T5869-","A5870-","A5871-","T5872-","G5873-","C5874-","A5875-","G5876-","A5877-","T5878-","A5879-","T5880-","A5881-","A5882-","T5883-","A5884-","T5885-","C5886-","T5887-","T5888-","T5889-","A5890-","T5891-","A5892-","T5893-","G5894-","T5895-","A5896-","A5897-","T5898-","A5899-","T5900-","A5901-","T5902-","G5903-","C5904-","A5905-","A5906-","A5907-","C5908-","A5909-","G5910-","T5911-","C5912-","T5913-","A5914-","T5915-","C5916-","T5917-","A5918-","C5919-","T5920-","A5921-","T5922-","A5923-","T5924-","A5925-","C5926-","T5927-","G5928-","A5929-","T5930-","C5931-","A5932-","A5933-","T5934-","A5935-","T5936-","T5937-","A5938-","T5939-","C5940-","T5941-","C5942-","T5943-","A5944-","T5945-","G5946-","A5947-","A5948-","T5949-","C5950-","C5951-","T5952-","A5953-","A5954-","A5955-","A5956-","T5957-","A5958-","A5959-","T5960-","C5961-","A5962-","T5963-","A5964-","C5965-","A5966-","G5967-","A5968-","A5969-","C5970-","A5971-","T5972-","C5973-","T5974-","A5975-","C5976-","A5977-","G5978-","G5979-","A5980-","T5981-","C5982-","A5983-","C5984-","A5985-","A5986-","A5987-","T5988-","T5989-","G5990-","G5991-","T5992-","T5993-","C5994-","A5995-","A5996-","G5997-","G5998-","A5999-","G6000-","A6001-","A6002-","A6003-","T6004-","C6005-","T6006-","A6007-","T6008-","C6009-","A6010-","A6011-","A6012-","T6013-","A6014-","T6015-","T6016-","T6017-","T6018-","C6019-","C6020-","T6021-","G6022-","T6023-","C6024-","A6025-","A6026-","C6027-","A6028-","A6029-","C6030-","T6031-","G6032-","G6033-","T6034-","T6035-","C6036-","T6037-","A6038-","G6039-","A6040-","A6041-","C6042-","A6043-","T6044-","A6045-","A6046-","C6047-","A6048-","G6049-","T6050-","C6051-","A6052-","A6053-","C6054-","A6055-","C6056-","C6057-","T6058-","A6059-","A6060-","T6061-","C6062-","C6063-","A6064-","T6065-","G6066-","T6067-","T6068-","T6069-","T6070-","T6071-","T6072-","A6073-","T6074-","A6075-","G6076-","T6077-","C6078-","A6079-","T6080-","C6081-","T6082-","A6083-","C6084-","C6085-","A6086-","A6087-","A6088-","G6089-","A6090-","T6091-","A6092-","A6093-","T6094-","G6095-","A6096-","C6097-","C6098-","A6099-","A6100-","A6101-","G6102-","A6103-","T6104-","C6105-","G6106-","A6107-","G6108-","G6109-","T6110-","C6111-","G6112-","T6113-","C6114-","G6115-","T6116-","G6117-","A6118-","A6119-","A6120-","C6121-","T6122-","G6123-","C6124-","T6125-","C6126-","A6127-","T6128-","C6129-","G6130-","A6131-","C6132-","A6133-","G6134-","C6135-","C6136-","A6137-","T6138-","G6139-","A6140-","A6141-","A6142-","T6143-","C6144-","T6145-","G6146-","C6147-","C6148-","G6149-","A6150-","C6151-","T6152-","C6153-","C6154-","A6155-","T6156-","G6157-","G6158-","C6159-","G6160-","C6161-","G6162-","A6163-","A6164-","T6165-","C6166-","G6167-","C6168-","A6169-","C6170-","T6171-","G6172-","T6173-","C6174-","T6175-","T6176-","A6177-","T6178-","T6179-","C6180-","G6181-","C6182-","C6183-","A6184-","T6185-","T6186-","G6187-","A6188-","T6189-","T6190-","T6191-","T6192-","C6193-","A6194-","T6195-","T6196-","T6197-","T6198-","T6199-","T6200-","A6201-","T6202-","A6203-","A6204-","T6205-","T6206-","A6207-","T6208-","G6209-","T6210-","A6211-","C6212-","A6213-","T6214-","G6215-","T6216-","T6217-","T6218-","T6219-","C6220-","C6221-","T6222-","T6223-","C6224-","T6225-","C6231-","A6232-","A6233-","G6234-","A6235-","G6236-","T6237-","C6238-","T6239-","A6240-","C6241-","A6242-","A6243-","A6244-","A6245-","A6246-","T6247-","A6248-","T6249-","A6250-","T6251-","T6252-","T6253-","T6254-","T6255-","T6256-","C6257-","G6258-","A6259-","T6260-","A6261-","T6262-","C6263-","T6264-","A6265-","A6266-","G6267-","T6268-","A6269-","C6270-","T6271-","A6272-","A6273-","G6274-","T6275-","T6276-","T6277-","T6278-","T6279-","T6280-","A6282-","C6283-","T6284-","G6285-","T6286-","T6287-","T6288-","T6289-","T6290-","G6291-","T6292-","T6293-","A6294-","C6295-","T6296-","G6297-","T6298-","C6299-","T6300-","T6301-","C6302-","C6303-","A6304-","T6305-","T6306-","C6307-","T6308-","T6309-","C6310-","T6311-","A6312-","A6313-","C6314-","T6315-","A6316-","A6317-","A6318-","G6319-","A6320-","T6321-","C6322-","T6323-","G6324-","A6325-","G6326-","A6327-","T6328-","A6329-","A6330-","A6331-","T6332-","T6333-","A6334-","T6335-","A6336-","C6337-","A6338-","A6339-","T6340-","C6341-","T6342-","T6343-","C6344-","G6345-","C6346-","T6347-","A6348-","T6349-","C6350-","G6351-","A6352-","A6353-","C6354-","C6355-","A6356-","T6357-","T6358-","T6359-","T6360-","T6361-","G6362-","T6363-","A6364-","G6365-","T6366-","C6367-","T6368-","A6369-","A6370-","A6371-","G6372-","C6373-","C6374-","T6375-","G6376-","A6377-","A6378-","G6379-","T6380-","A6381-","A6382-","T6383-","T6384-","A6385-","A6386-","C6387-","C6388-","A6389-","A6390-","C6391-","T6392-","G6393-","T6394-","T6395-","T6396-","T6397-","T6398-","A6399-","T6400-","T6401-","A6402-","G6403-","T6404-","G6405-","G6406-","C6407-","T6408-","T6409-","T6410-","T6411-","T6412-","T6413-","C6414-","G6415-","A6416-","T6417-","C6418-","T6419-","A6420-","T6421-","C6422-","C6423-","T6424-","C6425-","G6426-","T6427-","C6428-","C6429-","T6430-","C6431-","A6434-","T6435-","C6436-","A6437-","T6438-","C6439-","C6440-","T6441-","T6442-","A6443-","T6444-","A6445-","T6446-","T6447-","A6448-","T6449-","T6450-","A6451-","T6452-","C6453-","A6454-","T6455-","T6456-","A6457-","T6458-","T6459-","A6460-","T6461-","C6462-","A6463-","T6464-","A6465-","G6466-","T6467-","C6468-","T6469-","A6470-","T6471-","T6472-","A6473-","A6474-","A6475-","C6476-","A6477-","C6478-","A6479-","A6480-","A6481-","T6482-","C6483-","A6484-","T6485-","C6486-","T6487-","A6488-","C6489-","G6490-","T6491-","T6492-","T6493-","A6494-","T6495-","A6496-","A6497-","C6498-","A6499-","A6500-","C6501-","A6502-","T6503-","T6504-","C6505-","T6506-","C6507-","A6508-","T6509-","T6510-","A6511-","T6512-","T6513-","A6514-","A6515-","T6516-","T6517-","A6518-","G6519-","T6520-","T6521-","C6522-","T6523-","G6524-","T6525-","A6526-","G6527-","A6528-","A6529-","T6530-","A6531-","T6532-","C6533-","T6534-","T6535-","T6536-","A6537-","A6538-","T6539-","A6540-","A6541-","T6542-","T6543-","T6544-","G6545-","G6546-","C6547-","T6548-","A6549-","T6550-","A6551-","C6552-","A6553-","T6554-","C6555-","T6556-","G6557-","T6558-","T6559-","C6560-","A6561-","A6562-","T6563-","A6564-","C6565-","T6566-","A6567-","T6568-","C6569-","T6570-","A6571-","T6572-","T6573-","G6574-","A6575-","T6576-","G6577-","A6578-","T6579-","T6580-","T6581-","C6582-","T6583-","T6584-","T6585-","T6586-","T6587-","T6588-","A6589-","A6590-","G6591-","A6592-","C6593-","T6594-","T6595-","A6596-","A6597-","A6598-","C6599-","T6600-","A6601-","G6602-","T6603-","T6604-","A6605-","T6606-","G6607-","G6608-","T6609-","A6610-","A6611-","T6612-","G6613-","A6614-","C6615-","G6616-","A6617-","T6618-","G6619-","A6620-","A6621-","A6622-","T6623-","C6624-","G6625-","A6626-","G6627-","T6628-","A6629-","G6630-","T6631-","A6632-","A6633-","C6634-","T6635-","T6636-","C6637-","T6638-","A6639-","A6640-","T6641-","A6642-","A6643-","A6644-","G6645-","A6646-","C6647-","T6648-","T6649-","G6650-","A6651-","T6652-","A6653-","T6654-","C6655-","A6656-","T6657-","T6658-","A6659-","T6660-","C6661-","A6662-","T6663-","A6664-","T6665-","G6666-","T6667-","T6668-","T6669-","G6670-","A6671-","T6672-","C6673-","G6674-","T6675-","C6676-","A6677-","T6678-","A6679-","G6680-","T6681-","T6682-","A6683-","A6684-","T6685-","A6686-","G6687-","T6688-","G6689-","T6690-","G6691-","G6692-","C6693-","T6694-","A6695-","A6696-","A6697-","T6698-","G6699-","G6700-","T6701-","A6702-","C6703-","T6704-","G6705-","T6706-","T6707-","A6708-","A6709-","T6710-","A6711-","A6712-","G6713-","T6714-","T6715-","T6716-","A6717-","T6718-","A6719-","G6720-","A6721-","C6722-","A6723-","A6724-","T6725-","A6726-","T6727-","C6728-","A6729-","T6730-","A6731-","G6732-","T6733-","A6734-","T6735-","T6736-","T6737-","T6738-","C6739-","T6740-","T6741-","T6742-","C6743-","C6744-","A6745-","G6746-","A6747-","A6748-","T6749-","T6750-","A6751-","G6752-","A6753-","T6754-","T6755-","A6756-","T6757-","T6758-","T6759-","T6760-","T6761-","T6762-","T6763-","A6764-","A6765-","A6766-","T6767-","A6768-","C6769-","T6770-","G6771-","A6772-","T6773-","C6774-","C6775-","T6776-","C6777-","A6778-","C6779-","A6780-","A6781-","T6782-","T6783-","C6784-","C6785-","G6786-","T6787-","G6788-","A6789-","T6790-","G6791-","T6792-","A6793-","G6794-","C6795-","A6796-","G6797-","T6798-","A6799-","G6800-","T6801-","T6802-","G6803-","G6804-","T6805-","G6806-","C6807-","A6808-","T6809-","G6810-","G6811-","T6812-","C6813-","T6814-","A6815-","T6816-","A6817-","T6818-","C6819-","G6820-","T6821-","T6822-","A6823-","A6824-","A6825-","A6826-","T6827-","G6828-","T6829-","A6830-","T6831-","C6832-","A6833-","T6834-","A6835-","T6836-","A6837-","T6838-","A6839-","A6840-","T6841-","A6842-","G6843-","T6844-","T6845-","T6846-","T6847-","C6848-","T6849-","G6850-","A6851-","C6852-","G6853-","T6854-","G6855-","G6856-","A6857-","G6858-","T6859-","A6860-","C6861-","A6862-","G6863-","A6864-","A6865-","T6866-","T6867-","T6868-","T6869-","C6870-","G6871-","A6872-","T6873-","T6874-","A6875-","A6876-","T6877-","G6878-","A6879-","G6880-","T6881-","T6882-","C6883-","A6884-","T6885-","G6886-","G6887-","T6888-","A6889-","A6890-","G6891-","G6892-","A6893-","A6894-","G6895-","G6896-","G6897-","C6898-","A6899-","A6900-","A6901-","T6902-","G6903-","T6904-","C6905-","T6906-","G6907-","T6908-","A6909-","T6910-","A6911-","T6912-","A6913-","A6914-","T6915-","A6916-","T6917-","A6918-","C6919-","A6920-","T6921-","A6922-","A6923-","G6924-","T6925-","T6926-","A6927-","A6928-","T6929-","A6930-","G6931-","T6932-","T6933-","T6934-","T6935-","T6936-","A6938-","T6939-","C6940-","A6941-","T6942-","A6943-","T6944-","T6945-","T6946-","T6947-","C6948-","T6949-","A6950-","A6951-","T6952-","A6953-","C6954-","C6955-","A6956-","T6957-","A6958-","A6959-","T6960-","A6961-","A6962-","A6963-","A6964-","A6965-","T6966-","T6967-","A6968-","T6969-","C6970-","A6971-","T6972-","T6973-","A6974-","T6975-","T6976-","G6977-","C6978-","G6979-","T6980-","T6981-","T6982-","G6983-","G6984-","T6985-","A6986-","G6987-","A8366C","G8599A","G10923A","T12181A","T15127-","C17933T","T18703C","C21073A","C29763T","G33053A","A35238G","A38984G","G46402T","G47539A","C47904-","C47905-","G64207A","T66182C","G69898A","A88356G","G102985T","C109017T","C115292T","G133070A","A136512C","T136555-","A136556-","T136557-","G136558-","A136559-","T136560-","A136561-","T136562-","C136563-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","C142360T","C145930-","G148718A","C152844T","C158803A","C159989T","C160938T","C166345A","G167529T","G169595A","-169721A","-169723A","-169725A","-169726T","A172087T","A173273-","A173274-","T173275-","A173276-","T173277-","A173278-","T173279-","A173280-","T173281-","A173282-","T173283-","A173284-","T173285-","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","C174599T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C192693T","C195135T"],"OPG002":["A226V"],"OPG002_dup":["A226V"],"OPG023":["Q660*"],"OPG031":["C299Y"],"OPG047":["D478N"],"OPG065":["R28S"],"OPG153":["D370-","I371-","D372-","D373-","D374-","D375-","D376-","D377-","D378-","Y386D"],"OPG187":["A106V"],"OPG191":["S62*"],"OPG193":["D66Y"],"OPG204":["A23V"]},"labels":{"aa":"OPG002: A226V; OPG002_dup: A226V; OPG023: Q660*; OPG031: C299Y; OPG047: D478N; OPG065: R28S; OPG153: D370-, I371-, D372-, D373-, D374-, D375-, D376-, D377-, D378-, Y386D; OPG187: A106V; OPG191: S62*; OPG193: D66Y; OPG204: A23V"}}},{"name":"NODE_0000005","node_attrs":{"div":297,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G8394T","C10147T","G11051A","G15606A","G18280A","G21146T","T32747C","G36045T","C39311G","A45542G","G84665A","A92711G","G114697T","G135808A","A136537-","T136538-","C136539-","A136540-","T136541-","C136542-","-140134A","-140135A","-140136C","-140137A","-140138A","-140139T","-140140T","-140141A","-140142T","C145551G","C148484T","T148958C","C156205T","A156206C","-156210A","C169722-","G169724-","C170542T","A172885-","-173286A","-173287T","-173288A","-173289T","-173290A","-173291T","-173292A","-173293T","-173294A","G173318-","G173595A","G176943A","C188468T","A188511G","C190447T","A190935-","T190984-","A190985-","G190986-","A190987-","A190988-","A192419-","A192420-","G192421-","T192422-","C192423-","A192424-","T192425-","A192426-","A192427-","G192428-","T192429-","T192430-","A192431-","G192432-","T192433-","T192434-"],"OPG016":["A13V","T176-"],"OPG023":["A617V"],"OPG037":["H430N"],"OPG055":["L347I"],"OPG133":["P334T"],"OPG153":["D372I","D381-","D382-","D383-","D384-","D385-"],"OPG159":["-124N","-125Y","-126N"],"OPG197":["T18-","D19-"],"OPG198":["H169Y"],"OPG205":["A430T"]},"labels":{"aa":"OPG016: A13V, T176-; OPG023: A617V; OPG037: H430N; OPG055: L347I; OPG133: P334T; OPG153: D372I, D381-, D382-, D383-, D384-, D385-; OPG159: -124N, -125Y, -126N; OPG197: T18-, D19-; OPG198: H169Y; OPG205: A430T"}},"children":[{"name":"KJ642619","node_attrs":{"div":299,"accession":"KJ642619","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"Gabon"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"KJ642619"},"date":{"value":"1988-XX-XX"},"strain_display":{"value":"Gabon/KJ642619/1988-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A24147T","T24148A"]}}},{"name":"OP498046","node_attrs":{"div":301,"accession":"OP498046","author":{"author":"Emmerich,P.,Bialonski,A.,Tomazatos,A.,Cadar,D.","value":"Emmerich,P.,Bialonski,A.,Tomazatos,A.,Cadar,D."},"country":{"value":"Gabon"},"institution":{"value":"Bernhard Nocht Institute for Tropical Medicine, Arbovirology and Entomology"},"strain":{"value":"BNITM-Gabon1988"},"host":{"value":"Homo sapiens"},"date":{"value":"1988-XX-XX"},"strain_display":{"value":"Gabon/OP498046/1988-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G11865C","T24612C","C151380T","G171690A"],"OPG023":["L346V"],"OPG199":["D235N"]},"labels":{"aa":"OPG023: L346V; OPG199: D235N"}}}]}]},{"name":"NODE_0000006","node_attrs":{"div":278,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G40182A","C54569A","G56397T","C57678T","C87267T","C109535A","G122405A","A134326G","G145959A","G146433A","A165096G","A179236G","G187305A"],"OPG057":["A5V"],"OPG072":["L34I"],"OPG143":["A304V"],"OPG170":["H116Y"]},"labels":{"aa":"OPG057: A5V; OPG072: L34I; OPG143: A304V; OPG170: H116Y"}},"children":[{"name":"KJ642612","node_attrs":{"div":300,"accession":"KJ642612","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"KJ642612"},"date":{"value":"1986-XX-XX"},"strain_display":{"value":"Democratic Republic of the Congo/KJ642612/1986-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G18301A","C29763T","G31718A","T33822A","G35972T","G39173A","G53569A","G53953A","T77412A","T90138C","A91005G","G96915A","G107670A","C117896T","C128183A","-148336T","G150582T","T151256A","T151769C","-169721A","-169723A","-169725A","-169726T","A172087T","C176495T","A179137G","C179145T","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","A181253-","C181619T","T187676C","T187975-","A187976-","A190302G","G197006T"],"OPG047":["D478N"],"OPG054":["P9T"]},"labels":{"aa":"OPG047: D478N; OPG054: P9T"}}},{"name":"NODE_0000007","node_attrs":{"div":291,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T622-","C5340T","C8344A","C15209A","C21369A","T52086C","A71178-","C76021T","T82313C","G98856A","G122351A","G129583T","T150936C","G154730A","C169722-","G169724-","C169758T","A169777-","G169778-","A169779-","A169780-","G169781-","A169782-","T169783-","A169784-","T169785-","C169786-","A169787-","T169788-","G169789-","A169790-","A169791-","C169792-","G169793-","A169794-","A169795-","A169796-","C171561T","-179227G","G191870A","A196593-"],"OPG015":["A273T"],"OPG015_dup":["A273T"],"OPG025":["S20I"],"OPG037":["M355I"],"OPG071":["N785D"],"OPG143":["A322V"],"OPG181":["A107T"],"OPG197":["T18-","D19-","T30I","E37-","D38-","I39-","M40-","N41-","E42-","I43-"],"OPG199":["P192S"]},"labels":{"aa":"OPG015: A273T; OPG015_dup: A273T; OPG025: S20I; OPG037: M355I; OPG071: N785D; OPG143: A322V; OPG181: A107T; OPG197: T18-, D19-, T30I, E37-, D38-, I39-, M40-, N41-, E42-, I43-; OPG199: P192S"}},"children":[{"name":"NODE_0000008","node_attrs":{"div":292,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C19745T"]}},"children":[{"name":"NC_003310","node_attrs":{"div":388,"accession":"NC_003310","author":{"author":"Senkevich,T.G.,Yutin,N.,Wolf,Y.I.,Koonin,E.V.,Moss,B.,Zmasek,C.M.,Knipe,D.M.,Pellett,P.E.,Scheuermann,R.H.,Shchelkunov,S.N.,Totmenin,A.V.,Babkin,I.V.,Safronov,P.F.,Ryazankina,O.I.,Petrov,N.A.,Gutorov,V.V.,Uvarova,E.A.,Mikheev,M.V.,Sisler,J.R.,Esposito,J.J.,Jahrling,P.B.,Sandakhchiev,L.S.","value":"Senkevich,T.G.,Yutin,N.,Wolf,Y.I.,Koonin,E.V.,Moss,B.,Zmasek,C.M.,Knipe,D.M.,Pellett,P.E.,Scheuermann,R.H.,Shchelkunov,S.N.,Totmenin,A.V.,Babkin,I.V.,Safronov,P.F.,Ryazankina,O.I.,Petrov,N.A.,Gutorov,V.V.,Uvarova,E.A.,Mikheev,M.V.,Sisler,J.R.,Esposito,J.J.,Jahrling,P.B.,Sandakhchiev,L.S."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Department of Molecular Biology of Genomes, SRC VB Vector, Russia"},"strain":{"value":"NC_003310"},"host":{"value":"Homo sapiens"},"date":{"value":"1996-XX-XX"},"strain_display":{"value":"Democratic Republic of the Congo/NC_003310/1996-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T2688A","G9441A","A24393T","C24945T","C26416T","A27114-","T27328C","C29029T","T29031C","T29753C","T29758C","T30743A","T30815A","T30855A","G32024A","A32322G","T32329C","T33159C","G34800A","T34944A","G35230A","G35775A","T37957A","C38427T","T38658A","A39070T","T39072A","-39076T","T39447C","A40487T","A50294G","G59966C","T60903A","C60947T","T61241C","A61926C","T62169A","G62941T","T65141C","T65870C","A67348G","C67353T","A70503T","T71422C","A73777T","T74112C","A75351T","C76284T","T78525C","A81969-","C82417T","T82548C","T82641G","C83956T","G88318A","T108302C","A115794G","T122451C","T122935C","T122986C","T124980C","T125566C","T125834C","T126192C","T126231C","T126963C","T130725C","A130822C","G134912A","T136637C","T138948C","T139755C","T140893C","T141277A","A141901G","G142068A","A143024T","G143126A","A143187T","A143703G","C143806T","T143895C","C158963T","G161650A","T165054-","C165055-","G166518A","C167064T","T168214-","A168962-","A169025-","T169165-","A169581-","T169894C","A170077G","C182952T","T182953C","C183492A","C183522A","C184979T","A185373G","G185472A","T186503C","T186531G","C186532T","A187305G","A194522T"],"OPG002":["I22L"],"OPG002_dup":["I22L"],"OPG042":["G228R"],"OPG043":["N210D"],"OPG045":["R78G"],"OPG047":["N114Y","E127V","H151L","E481G"],"OPG049":["T275A","M277T"],"OPG054":["A256V"],"OPG056":["N126I","C203Y","T360S"],"OPG057":["N250S"],"OPG059":["Y49*"],"OPG080":["S260G","G358R","P685A"],"OPG082":["T171K"],"OPG085":["L395P"],"OPG089":["K213I"],"OPG091":["F18S"],"OPG097":["D198N"],"OPG101":["F14L"],"OPG105":["K282-","A431V","C475R","Y506D","S944F"],"OPG109":["A377V"],"OPG127":["K175R"],"OPG143":["T289A"],"OPG145":["L345P"],"OPG146":["D25G"],"OPG147":["S52G"],"OPG151":["M601T","E633D"],"OPG153":["N344S"],"OPG156":["I154M"],"OPG160":["K61R"],"OPG161":["L59Q"],"OPG162":["R84G"],"OPG164":["N83Y","E117K","Q137L"],"OPG165":["D63G","I127T"],"OPG185":["A16V"],"OPG188":["G19R"],"OPG191":["A120T"],"OPG192":["H112Y"],"OPG198":["K14E"],"OPG210":["L533S","P713T","P723T","T1340A","A1373T","S1726V"]},"labels":{"aa":"OPG002: I22L; OPG002_dup: I22L; OPG042: G228R; OPG043: N210D; OPG045: R78G; OPG047: N114Y, E127V, H151L, E481G; OPG049: T275A, M277T; OPG054: A256V; OPG056: N126I, C203Y, T360S; OPG057: N250S; OPG059: Y49*; OPG080: S260G, G358R, P685A; OPG082: T171K; OPG085: L395P; OPG089: K213I; OPG091: F18S; OPG097: D198N; OPG101: F14L; OPG105: K282-, A431V, C475R, Y506D, S944F; OPG109: A377V; OPG127: K175R; OPG143: T289A; OPG145: L345P; OPG146: D25G; OPG147: S52G; OPG151: M601T, E633D; OPG153: N344S; OPG156: I154M; OPG160: K61R; OPG161: L59Q; OPG162: R84G; OPG164: N83Y, E117K, Q137L; OPG165: D63G, I127T; OPG185: A16V; OPG188: G19R; OPG191: A120T; OPG192: H112Y; OPG198: K14E; OPG210: L533S, P713T, P723T, T1340A, A1373T, S1726V"}}},{"name":"JX878418","node_attrs":{"div":303,"accession":"JX878418","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0120"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-01-02"},"strain_display":{"value":"Democratic Republic of the Congo/JX878418/2007-01-02"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G1934A","A50236G","G60803T","G74360A","G95577A","G116628T","C120371T","C151006A","C174070T","G187369A","A187951C","C195276T"],"OPG002":["T273M"],"OPG002_dup":["T273M"],"OPG069":["Q84R"],"OPG080":["L406I"],"OPG094":["R194H"],"OPG116":["D73N"],"OPG134":["*293Y"],"OPG135":["S95Y"],"OPG137":["A257V"]},"labels":{"aa":"OPG002: T273M; OPG002_dup: T273M; OPG069: Q84R; OPG080: L406I; OPG094: R194H; OPG116: D73N; OPG134: *293Y; OPG135: S95Y; OPG137: A257V"}}}]},{"name":"NODE_0000009","node_attrs":{"div":292,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G32003A"]}},"children":[{"name":"JX878426","node_attrs":{"div":301,"accession":"JX878426","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0450"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-05-27"},"strain_display":{"value":"Democratic Republic of the Congo/JX878426/2007-05-27"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G19563A","G38096T","G54227A","-71178A","A72767T","G111583A","T121790C","A160337-","C166976T","C185501T","G189591A"],"OPG005":["M131I"],"OPG034":["A148V"],"OPG071":["T71I"],"OPG092":["S61T"],"OPG130":["T107I"],"OPG141":["I45M"]},"labels":{"aa":"OPG005: M131I; OPG034: A148V; OPG071: T71I; OPG092: S61T; OPG130: T107I; OPG141: I45M"}}},{"name":"JX878408","node_attrs":{"div":292,"accession":"JX878408","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 06-0970"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-10-31"},"strain_display":{"value":"Democratic Republic of the Congo/JX878408/2006-10-31"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000010","node_attrs":{"div":297,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C7495-","A7496-","A7497-","T7498-","T7499-","A7500-","G24032A","G94972A","G137606T","C149206G","G160867A","C170296A"],"OPG115":["V105I"],"OPG153":["A21E"],"OPG174":["E64Q"],"OPG198":["L87M"]},"labels":{"aa":"OPG115: V105I; OPG153: A21E; OPG174: E64Q; OPG198: L87M"}},"children":[{"name":"JX878420","node_attrs":{"div":297,"accession":"JX878420","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0283"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-02-26"},"strain_display":{"value":"Democratic Republic of the Congo/JX878420/2007-02-26"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A8054-"]}}},{"name":"JX878419","node_attrs":{"div":297,"accession":"JX878419","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0275"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-02-10"},"strain_display":{"value":"Democratic Republic of the Congo/JX878419/2007-02-10"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000011","node_attrs":{"div":267,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T458-","A459-","G460-","C7756A","-140134A","-140135A","-140136C","-140137A","-140138A","-140139T","-140140T","-140141A","-140142T","-146863A","-146864T","-146884T","-146885T","-146886T","-146887A","-146888T","-146889A","-146890T","-146891T","-146892T","-146893T","-146894A","-146895T","G150568-","-169721A","-169723A","-169725A","-169726T","-179227A","C196750-","T196751-","A196752-"],"OPG159":["-124N","-125Y","-126N"]},"labels":{"aa":"OPG159: -124N, -125Y, -126N"}},"children":[{"name":"NODE_0000012","node_attrs":{"div":276,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C204A","C790T","C115912T","G148121A","A148344T","G152154A","C155631A","G169205T","C176693T","C177720T","G186892T","G196420A"],"OPG153":["P390L"],"OPG173":["V29I"],"OPG205":["R689C"],"OPG210":["R1846I"]},"labels":{"aa":"OPG153: P390L; OPG173: V29I; OPG205: R689C; OPG210: R1846I"}},"children":[{"name":"KP849471","node_attrs":{"div":287,"accession":"KP849471","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Yoshinori,N.,Muyembe,J.-J.,Kingbeni,P.M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Yoshinori,N.,Muyembe,J.-J.,Kingbeni,P.M."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"Yambuku_DRC_1985"},"date":{"value":"1985-XX-XX"},"strain_display":{"value":"Democratic Republic of the Congo/KP849471/1985-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G3975A","G12958A","A17046T","G60368A","C83195T","G85079A","G86364A","G133454A","T148337-","G150484A","-150568G","G150582T","G156302A","G180598A","C193235T","G197006T"],"OPG029":["D8E"],"OPG080":["P551S"],"OPG176":["D226N"]},"labels":{"aa":"OPG029: D8E; OPG080: P551S; OPG176: D226N"}}},{"name":"NODE_0000013","node_attrs":{"div":282,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T8510C","C16123A","C51889T","T87138C","G136499A","A146877T","T146880A","G151145A","T178510-"],"OPG027":["E85D"]},"labels":{"aa":"OPG027: E85D"}},"children":[{"name":"JX878410","node_attrs":{"div":283,"accession":"JX878410","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 06-1070"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-11-24"},"strain_display":{"value":"Democratic Republic of the Congo/JX878410/2006-11-24"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T8470C","-8471T","-148336T"]}}},{"name":"NODE_0000014","node_attrs":{"div":295,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T7058G","G16406A","G24032A","C69800T","T71738C","C79473A","G104054T","G141897A","G153208A","C162040T","C163571T","G165428A","A170972-","-178510T","A181253-","T183992C","A186633G","A189692-"],"OPG088":["A22T"],"OPG102":["P130H"],"OPG180":["A173T"],"OPG188":["L149F"],"OPG189":["A80V"],"OPG190":["G103S"],"OPG210":["T1760A"]},"labels":{"aa":"OPG088: A22T; OPG102: P130H; OPG180: A173T; OPG188: L149F; OPG189: A80V; OPG190: G103S; OPG210: T1760A"}},"children":[{"name":"JX878412","node_attrs":{"div":298,"accession":"JX878412","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 06-1076"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-11-30"},"strain_display":{"value":"Democratic Republic of the Congo/JX878412/2006-11-30"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G15850T","C99681T","C129086T"],"OPG151":["P55S"]},"labels":{"aa":"OPG151: P55S"}}},{"name":"NODE_0000015","node_attrs":{"div":296,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T6937-","G115548A"],"OPG133":["P50L"]},"labels":{"aa":"OPG133: P50L"}},"children":[{"name":"JX878411","node_attrs":{"div":296,"accession":"JX878411","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 06-1075"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-11-30"},"strain_display":{"value":"Democratic Republic of the Congo/JX878411/2006-11-30"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}},{"name":"JX878409","node_attrs":{"div":296,"accession":"JX878409","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 06-0999"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-11-09"},"strain_display":{"value":"Democratic Republic of the Congo/JX878409/2006-11-09"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000016","node_attrs":{"div":293,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G1750A","G11111A","G14622A","C25557T","C47009T","T49703C","C85076T","G140367T","-148336T","C173464T","C188051T","G190541A","C195460T"],"OPG023":["A597V"],"OPG025":["R216C"]},"labels":{"aa":"OPG023: A597V; OPG025: R216C"}},"children":[{"name":"JX878422","node_attrs":{"div":295,"accession":"JX878422","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0287"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-03-20"},"strain_display":{"value":"Democratic Republic of the Congo/JX878422/2007-03-20"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A66164C","C144356T"],"OPG084":["Q481H"]},"labels":{"aa":"OPG084: Q481H"}}},{"name":"NODE_0000017","node_attrs":{"div":294,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C187388G"]}},"children":[{"name":"JX878428","node_attrs":{"div":294,"accession":"JX878428","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0514"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-06-30"},"strain_display":{"value":"Democratic Republic of the Congo/JX878428/2007-06-30"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000018","node_attrs":{"div":296,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T8470C","-8471T","A14622G"],"OPG025":["C216R"]},"labels":{"aa":"OPG025: C216R"}},"children":[{"name":"JX878427","node_attrs":{"div":296,"accession":"JX878427","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0480"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-05-25"},"strain_display":{"value":"Democratic Republic of the Congo/JX878427/2007-05-25"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C144356-"]}}},{"name":"JX878421","node_attrs":{"div":297,"accession":"JX878421","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0286"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-03-22"},"strain_display":{"value":"Democratic Republic of the Congo/JX878421/2007-03-22"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G174812T"],"OPG204":["R94M"]},"labels":{"aa":"OPG204: R94M"}}},{"name":"JX878416","node_attrs":{"div":297,"accession":"JX878416","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0093"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-12-26"},"strain_display":{"value":"Democratic Republic of the Congo/JX878416/2006-12-26"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G50130A"],"OPG069":["D49N"]},"labels":{"aa":"OPG069: D49N"}}},{"name":"JX878415","node_attrs":{"div":296,"accession":"JX878415","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0092"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-12-26"},"strain_display":{"value":"Democratic Republic of the Congo/JX878415/2006-12-26"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}},{"name":"JX878414","node_attrs":{"div":296,"accession":"JX878414","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0046"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-12-14"},"strain_display":{"value":"Democratic Republic of the Congo/JX878414/2006-12-14"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}},{"name":"JX878413","node_attrs":{"div":296,"accession":"JX878413","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0045"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-12-14"},"strain_display":{"value":"Democratic Republic of the Congo/JX878413/2006-12-14"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}}]}]}]}]}]},{"name":"NODE_0000020","node_attrs":{"div":271,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G1319T","-46648T","G70874A","C130660T","G135598A","G144341-","-148336T","T159792C","C195891A"],"OPG001":["T86N"],"OPG001_dup":["T86N"],"OPG089":["E337K"]},"labels":{"aa":"OPG001: T86N; OPG001_dup: T86N; OPG089: E337K"}},"children":[{"name":"NODE_0000021","node_attrs":{"div":276,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["-8993A","C8994-","A56010G","C81524T","C94783T","C141329T","G148121A","G150582-","A150583-","T150584-","G150585-","A150586-"],"OPG115":["H42Y"],"OPG173":["V29I"]},"labels":{"aa":"OPG115: H42Y; OPG173: V29I"}},"children":[{"name":"NODE_0000022","node_attrs":{"div":279,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G6645T","G108249A","A133978-","A133979-","C133980-","T148343A","-173286A","-173287T","A184202C"],"OPG127":["H193Y"]},"labels":{"aa":"OPG127: H193Y"}},"children":[{"name":"KC257460","node_attrs":{"div":286,"accession":"KC257460","author":{"author":"Nakazawa,Y.,Emerson,G.L.,Carroll,D.S.,Zhao,H.,Li,Y.,Reynolds,M.G.,Karem,K.L.,Olson,V.A.,Lash,R.R.,Davidson,W.B.,Smith,S.K.,Levine,R.S.,Regnery,R.L.,Sammons,S.A.,Frace,M.A.,Mutasim,E.M.,Karsani,M.E.,Muntasir,M.O.,Babiker,A.A.,Opoka,L.,Chowdhary,V.,Damon,I.K.,Karsani,M.E.M.","value":"Nakazawa,Y.,Emerson,G.L.,Carroll,D.S.,Zhao,H.,Li,Y.,Reynolds,M.G.,Karem,K.L.,Olson,V.A.,Lash,R.R.,Davidson,W.B.,Smith,S.K.,Levine,R.S.,Regnery,R.L.,Sammons,S.A.,Frace,M.A.,Mutasim,E.M.,Karsani,M.E.,Muntasir,M.O.,Babiker,A.A.,Opoka,L.,Chowdhary,V.,Damon,I.K.,Karsani,M.E.M."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Biochemistry & Microbiology, University of Victoria, Canada"},"strain":{"value":"KC257460"},"host":{"value":"Homo sapiens"},"date":{"value":"1985-XX-XX"},"strain_display":{"value":"Democratic Republic of the Congo/KC257460/1985-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A461-","T462-","T463-","G464-","G465-","C466-","A581G","G582-","A583-","T12940-","A12941-","A21066G","G45419T","G46543A","C55215T","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","G164590A","C169530A","-170918G","G182700T","G183510-","T183511-","C183512-","C183513-","A183514-","A183515-","A183516-","A183517-","T183518-","C183519-","C183520-","G183521-","C183522-","C183523-","A183524-","C183525-","A183526-","A183527-","C183528-","T183529-","T183530-","C183531-","C183532-","C183533-","C183534-","C183535-","T183536-","A183537-","G183538-","A183539-","C183540-","C183541-","A183542-","T196627C","C196630-","T196631-","G196744-","C196745-","C196746-","A196747-","A196748-","T196749-"],"OPG153":["I370D","I371D","D372I","D373I"],"OPG189":["A420T"],"OPG197":["V36T"],"OPG210":["G449C","Q720-","N721-","P722-","P723-","Q724-","L725-","P726-","P727-","R728-","P729-","V730-"]},"labels":{"aa":"OPG153: I370D, I371D, D372I, D373I; OPG189: A420T; OPG197: V36T; OPG210: G449C, Q720-, N721-, P722-, P723-, Q724-, L725-, P726-, P727-, R728-, P729-, V730-"}}},{"name":"NODE_0000023","node_attrs":{"div":290,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C204A","G6146A","T11318C","C19628T","C33967G","T35962C","A42121C","T46648-","C126969T","C138190A","G166163A","G171413A","-173288A","-173289T","-173290A","-173291T","-173292A","-173293T","-173294A","-173295T","-173296A","-173297T","-173298A","-173299T","-173300A","-173301T","C178333T","A179227G","A179236G","C191064T","G197006T"],"OPG015":["A4V"],"OPG015_dup":["A4V"],"OPG023":["Y528C"],"OPG052":["S10T"],"OPG054":["Q12R"],"OPG155":["R101I"],"OPG191":["M1I"],"OPG199":["M142I"]},"labels":{"aa":"OPG015: A4V; OPG015_dup: A4V; OPG023: Y528C; OPG052: S10T; OPG054: Q12R; OPG155: R101I; OPG191: M1I; OPG199: M142I"}},"children":[{"name":"HM172544","node_attrs":{"div":332,"accession":"HM172544","author":{"author":"Farlow,J.,Ichou,M.A.,Huggins,J.,Ibrahim,S.,Ait Ichou,M.,Ibrahims,S.","value":"Farlow,J.,Ichou,M.A.,Huggins,J.,Ibrahim,S.,Ait Ichou,M.,Ibrahims,S."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Virology, The United States Army Medical Research Institute for Infectious Diseases (USAMRIID), USA"},"strain":{"value":"Zaire 1979-005"},"host":{"value":"Homo sapiens"},"date":{"value":"1979-XX-XX"},"strain_display":{"value":"Democratic Republic of the Congo/HM172544/1979-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G6897A","C13503T","C24978-","T30041-","C31367T","T33413-","G33447A","C38066A","C42664T","A45990T","T48341A","T50745C","G51355A","T51682C","G52016A","C52389T","C52602T","G53498A","T56271C","A71178-","G75423A","C80549T","G81722A","A82190C","T83083G","G87216A","C87303T","T97494C","C100884T","C102551A","C105412T","G105605A","G116846A","C126632T","G126942A","A135122G","G147239A","C148546T","T149979C","G152106-","C162397T","C164144T","A166358T","T169140A","C175384T","T176564C","T183716C","T189840C"],"OPG025":["A589T"],"OPG051":["T68M"],"OPG063":["R342H"],"OPG070":["V256I"],"OPG071":["A314V","A613T","A684T","T808M"],"OPG095":["M207I"],"OPG105":["K355N","L653R"],"OPG109":["M715I"],"OPG120":["A289T"],"OPG122":["L42I"],"OPG124":["H122Y","S186N"],"OPG148":["S216L"],"OPG174":["A284T"],"OPG178":["G200-"],"OPG188":["H268Y"],"OPG189":["A271V"],"OPG191":["Q66H"]},"labels":{"aa":"OPG025: A589T; OPG051: T68M; OPG063: R342H; OPG070: V256I; OPG071: A314V, A613T, A684T, T808M; OPG095: M207I; OPG105: K355N, L653R; OPG109: M715I; OPG120: A289T; OPG122: L42I; OPG124: H122Y, S186N; OPG148: S216L; OPG174: A284T; OPG178: G200-; OPG188: H268Y; OPG189: A271V; OPG191: Q66H"}}},{"name":"DQ011155","node_attrs":{"div":290,"accession":"DQ011155","author":{"author":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S.","value":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Centers for Disease Control and Prevention, National Center for Infectious Diseases"},"strain":{"value":"Zaire_1979-005"},"host":{"value":"Homo sapiens"},"date":{"value":"1978-XX-XX"},"strain_display":{"value":"Democratic Republic of the Congo/DQ011155/1978-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000024","node_attrs":{"div":293,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T7092-","T7093-","A7094-","C7095-","A7096-","G7097-","T7098-","A7099-","T7100-","A7101-","T7102-","A7103-","C7104-","G7105-","T7106-","T7107-","A7108-","T7109-","T7110-","C8249T","C38214T","C52909T","C63123T","C82622T","C85325T","C85869T","C101013T","G109883A","G117995A","A118781G","C123585T","A125829G","G133473T","G146819-","T146866G","C165490T","C165639A","A184066G","G197132-","A197133-","A197149-","G197150-","A197151-","G197152-","T197153-","T197154-","T197155-","C197156-","C197157-","T197158-","A197159-","C197160-","G197161-","G197162-"],"OPG056":["S274N"],"OPG120":["V246M"],"OPG190":["A173D"],"OPG210":["K904R"]},"labels":{"aa":"OPG056: S274N; OPG120: V246M; OPG190: A173D; OPG210: K904R"}},"children":[{"name":"MT724770","node_attrs":{"div":295,"accession":"MT724770","author":{"author":"Marien,J.,Laudisoit,A.,Patrono,L.V.,Calvignac-Spencer,S.,Leendertz,F.,Leirs,H.,Verheyen,E.","value":"Marien,J.,Laudisoit,A.,Patrono,L.V.,Calvignac-Spencer,S.,Leendertz,F.,Leirs,H.,Verheyen,E."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Biology, Universiteit Antwerpen, Belgium"},"strain":{"value":"MT724770"},"host":{"value":"Crocidura littoralis"},"date":{"value":"2014-01-01"},"strain_display":{"value":"Democratic Republic of the Congo/MT724770/2014-01-01"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C204A","C133072T","T136555-","G136558C","-150582G","-150583A","-150584T","-150585G","-150586A","C159210T","G189214A"],"OPG005":["A6T"]},"labels":{"aa":"OPG005: A6T"}}},{"name":"NODE_0000025","node_attrs":{"div":294,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T7090-","T7091-","G7111-","T7112-","C7113-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T180483A"],"OPG159":["N124-","Y125-","N126-"]},"labels":{"aa":"OPG159: N124-, Y125-, N126-"}},"children":[{"name":"MN702449","node_attrs":{"div":294,"accession":"MN702449","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702449"},"host":{"value":"Homo sapiens"},"date":{"value":"2016-01-02"},"strain_display":{"value":"Central African Republic/MN702449/2016-01-02"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G146866T","T197117A","C197118G","T197121G","A197122T","T197123A","C197127A","A197129T","T197136A","T197138C","A197142T","C197144T","T197166A","G197167T"]}}},{"name":"MN702446","node_attrs":{"div":297,"accession":"MN702446","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702446"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-04-14"},"strain_display":{"value":"Central African Republic/MN702446/2018-04-14"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A8054-","G10673T","T37120-","G42785A","C179154T","A179162C","-179163C","-179164T","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A181253-","C181732G"],"OPG022":["D62E"],"OPG063":["P302S"],"OPG210":["T126S"]},"labels":{"aa":"OPG022: D62E; OPG063: P302S; OPG210: T126S"}}},{"name":"NODE_0000026","node_attrs":{"div":299,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["A8054-","G18952A","G87276A","C127584T","T148336-","T148337-","A148344T","A151042G","-197132G","-197133A","-197149A","-197150G","-197151A","-197152G","-197153T","-197154T","-197155T","-197156C","-197157C","-197158T","-197159A","-197160C","-197161G","-197162G"],"OPG149":["A130V"]},"labels":{"aa":"OPG149: A130V"}},"children":[{"name":"MN702445","node_attrs":{"div":299,"accession":"MN702445","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702445"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-02-06"},"strain_display":{"value":"Central African Republic/MN702445/2017-02-06"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","G197006T"]}}},{"name":"MN702444","node_attrs":{"div":299,"accession":"MN702444","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702444"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-02-06"},"strain_display":{"value":"Central African Republic/MN702444/2017-02-06"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000027","node_attrs":{"div":272,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G12632A","A146877T","T146880A"],"OPG023":["A90V"]},"labels":{"aa":"OPG023: A90V"}},"children":[{"name":"KJ642613","node_attrs":{"div":284,"accession":"KJ642613","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"KJ642613"},"date":{"value":"1970-XX-XX"},"strain_display":{"value":"Democratic Republic of the Congo/KJ642613/1970-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A581G","G582-","A583-","G7469A","C8249T","C13298T","C31628T","-41935T","C50527-","C50528-","T50529-","G50530-","C50531-","A50532-","T50533-","C50534-","T50535-","T50536-","A50537-","T50538-","T50539-","A50540-","G58413A","G63150A","C64611T","G66698T","C79369T","C111519T","G133968A","G144316T","G150582T","A150634-","A150635-","T178641-","T196627C","C196630-","T196631-"],"OPG083":["V36I"],"OPG153":["I371D"]},"labels":{"aa":"OPG083: V36I; OPG153: I371D"}}},{"name":"NODE_0000028","node_attrs":{"div":290,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G907A","G3308T","G11575A","T15747-","G31211A","G35067A","G37230T","T57906C","G60984A","G62421A","C87507T","C100648G","T101111C","G136039T","C137054T","A148344T","C154681T","G180556T","G181036A","G189591A","C193902A","C196303T"],"OPG005":["M131I"],"OPG047":["D478N"],"OPG056":["T602N"],"OPG119":["T88R"],"OPG120":["H213R"],"OPG153":["R205H"]},"labels":{"aa":"OPG005: M131I; OPG047: D478N; OPG056: T602N; OPG119: T88R; OPG120: H213R; OPG153: R205H"}},"children":[{"name":"DQ011154","node_attrs":{"div":292,"accession":"DQ011154","author":{"author":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S.","value":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S."},"country":{"value":"Republic of the Congo"},"institution":{"value":"National Center for Infectious Diseases, Centers for Disease Control and Prevention (US CDC), USA"},"strain":{"value":"Congo_2003_358"},"host":{"value":"Homo sapiens"},"date":{"value":"2003-XX-XX"},"strain_display":{"value":"Republic of the Congo/DQ011154/2003-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C204A","G140147A","T140154C","C150750T","C188925A","G197006T"],"OPG159":["C127Y"]},"labels":{"aa":"OPG159: C127Y"}}},{"name":"NODE_0000029","node_attrs":{"div":293,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["A5646G","T6219-","G24996A","C149078T","A189040-","A190994-","T191564C"],"OPG015":["C171R"],"OPG015_dup":["C171R"]},"labels":{"aa":"OPG015: C171R; OPG015_dup: C171R"}},"children":[{"name":"MN702451","node_attrs":{"div":300,"accession":"MN702451","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702451"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-04-14"},"strain_display":{"value":"Central African Republic/MN702451/2017-04-14"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G39626A","A65771T","G93521T","T146865A","A146868T","-150568G","G151440A","T155635-","T155636-","A155637-","G155638-","A155639-","T155640-","A155641-","G155642-","C165304T","C167244T","G171695A","C179163T","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","A179236G","T197117A","C197118G","T197121G","A197122T","T197123A","C197127A","A197129T","G197132-","A197133-","T197134-","T197135-","T197136-","T197137-","T197138-","C197139-","C197143T","C197147-","T197148-","A197149-","G197150-","A197151-","G197152-","T197153-","T197154-","T197155-","C197156-","C197157-","T197158-","A197159-","C197160-","G197161-","G197162-","T197163-","C197164-","G197165-","T197166-","G197167-","G197168-","G197169-","T197170-","C197171-","A197172-","C197173-","A197174-","C197175-","A197176-","T197177-","T197178-","T197179-","T197182C"],"OPG192":["H172Y"]},"labels":{"aa":"OPG192: H172Y"}}},{"name":"KP849469","node_attrs":{"div":295,"accession":"KP849469","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Yoshinori,N.,Muyembe,J.-J.,Kingbeni,P.M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Yoshinori,N.,Muyembe,J.-J.,Kingbeni,P.M."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"Boende_DRC_2008"},"date":{"value":"2008-XX-XX"},"strain_display":{"value":"Democratic Republic of the Congo/KP849469/2008-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A10459T","T10460-","A10461-","G135460T","G197006T"]}}}]},{"name":"NODE_0000030","node_attrs":{"div":293,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["A134C","C33905T","G40666C","T143617C","T146877A","A146880T","G150582-","A150583-","T150584-","G150585-","A150586-","T189889-","T189890-","A189891-","T189892-","T189893-","A189894-","C189895-","G189896-","T189897-","G189898-","A189899-","A189900-","G189901-","A189902-","T189903-","G189904-","A189905-","T189906-","A189907-","T189908-","C189909-","A189910-","T189911-","T189912-","A189913-","A189914-","A189915-","C189916-","C189917-","A189918-","A189919-","C189920-","A189921-","T189922-","T189923-","G189924-","A189925-","G189926-","A189927-","T189928-","T189929-","G189930-","G189931-","C189932-","T189933-","C189934-","T189935-","T189936-","A189937-","T189938-","G189939-","T189940-","T189941-","A189942-","G189943-","C189944-","T189945-","G189946-","G189947-","A189948-","T189949-","T189950-","G189951-","A189952-","A189953-","T189954-","T189955-","A189956-","C189957-","T189958-","G189959-","T189960-","A189961-","A189962-","T189963-","A189964-","A189965-","A189966-","T189967-","G189968-","C189969-","A189970-","T189971-","C189972-","G189973-","A189974-","G189975-","T189976-","A189977-","T189978-","A189979-","G189980-","A189981-","G189982-","G189983-","G189984-","A189985-","T189986-","A189987-","T189988-","A189989-","G189990-","C189991-","A189992-","A189993-","T189994-","T189995-","C189996-","T189997-","C189998-","G189999-","A190000-","T190001-","A190002-","A190003-","T190004-","A190005-","G190006-","T190007-","C190008-","A190009-","T190010-","G190011-","C190012-","A190013-","A190014-","T190015-","A190016-","T190017-","T190018-","T190019-","G190020-","A190021-","A190022-","T190023-","G190024-","A190025-","G190026-","A190027-","C190028-","T190029-","G190030-","A190031-","T190032-","A190033-","A190034-","T190035-","T190036-","T190037-","A190038-","G190039-","G190040-","T190041-","A190042-","A190043-","T190044-","A190045-","C190046-","A190047-","G190048-","T190049-","A190050-","C190051-","T190052-","A190053-","C190054-","A190055-","C190056-","A190057-","C190058-","A190059-","T190060-","A190061-","T190062-","C190063-","T190064-","T190065-","T190066-","C190067-","T190068-","A190069-","G190070-","A190071-","T190072-","T190073-","A190074-","T190075-","A190076-","T190077-","A190078-","T190079-","C190080-","G190081-","T190082-","T190083-","A190084-","A190085-","A190086-","A190087-","A190088-","T190089-","C190090-","T190091-","G190092-","T190093-","A190094-","A190095-","G190096-","A190097-","G190098-","G190099-","T190100-","A190101-","T190102-","A190103-","T190104-","T190105-","T190106-","C190107-","T190108-","C190109-","A190110-","T190111-","A190112-","A190113-","G190114-","T190115-","A190116-","T190117-","C190118-","C190119-","A190120-","C190121-","T190122-","G190123-","T190124-","G190125-","T190126-","A190127-","A190128-","T190129-","A190130-","T190131-","T190132-","A190133-","T190134-","T190135-","A190136-","A190137-","T190138-","G190139-","G190140-","A190141-","T190142-","A190143-","T190144-","A190145-","T190146-","A190147-","G190148-","A190149-","T190150-","A190151-","A190152-","C190153-","A190154-","C190155-","A190156-","A190157-","T190158-","A190159-","G190160-","G190161-","G190162-","A190163-","C190164-","T190165-","A190166-","A190167-","T190168-","A190169-","G190170-","T190171-","A190172-","T190173-","T190174-","G190175-","T190176-","A190177-","A190178-","A190179-","A190180-","G190181-","A190182-","T190183-","A190184-","T190185-","A190186-","A190187-","T190188-","C190189-","G190190-","A190191-","C190192-","T190193-","A190194-","T190195-","T190196-","T190197-","G190200-","T190201-","A190202-","C190203-","A190204-","T190205-","A190206-","T190207-","C190208-","C190209-","A190210-","G190211-","A190212-","T190213-","A190214-","T190215-","C190216-","T190217-","A190218-","T190219-","A190220-","T190221-","T190222-","C190223-","C190224-","T190225-","A190226-","C190227-","T190228-","A190229-","G190230-","T190231-","T190232-","T190233-","G190234-","C190235-","T190236-","G190237-","C190238-","G190239-","T190240-","A190241-","G190242-","T190243-","T190244-","G190245-","C190246-","A190247-","T190248-","C190249-","A190250-","T190251-","T190252-","G190253-","A190254-","T190255-","A190256-","T190257-","G190258-","C190259-","A190260-","T190261-","G190262-","A190263-","T190264-","T190265-","T190266-","A190267-","T190268-","C190269-","A190270-","G190271-","G190272-","A190273-","T190274-","T190275-","C190276-","A190277-","G190278-","A190279-","G190280-","A190281-","T190282-","G190283-","A190284-","A190285-","T190286-","T190287-","A190288-","C190289-","T190290-","A190291-","A190292-","G190293-","T190294-","A190295-","A190296-","A190297-","C190298-","T190299-","A190300-","C190301-","A190302-","A190303-","T190304-","C190305-","C190306-","C190307-","A190308-","C190309-","A190310-","A190311-","T190312-","A190313-","A190314-","G190315-","T190316-","A190317-","A190318-","G190319-","A190320-","A190321-","T190322-","C190323-","A190324-","A190325-","A190326-","T190327-","A190328-","T190329-","C190330-","A190331-","A190332-","A190333-","A190334-","A190335-","C190336-","T190337-","C190338-","A190339-","C190340-","T190341-","T190342-","T190343-","T190344-","G190345-","A190346-","T190347-","T190348-","T190349-","T190350-","T190351-","C190352-","T190353-","A190354-","G190355-","T190356-","C190357-","T190358-","T190359-","A190360-","A190361-","G190362-","T190363-","A190364-","A190365-","T190366-","A190367-","C190368-","A190369-","T190370-","A190371-","T190372-","A190373-","T190374-","T190375-","T190376-","A190377-","T190378-","T190379-","A190380-","A190381-","T190382-","A190383-","G190384-","A190385-","C190386-","C190387-","T190388-","A190389-","T190390-","G190391-","A190392-","A190393-","A190394-","T190395-","A190396-","A190397-","A190398-","A190399-","A190400-","A190401-","G190403-","T190404-","T190405-","A190406-","A190407-","C190408-","A190409-","A190410-","T190411-","G190412-","G190413-","A190414-","T190415-","T190416-","C190417-","G190418-","C190419-","G190420-","T190421-","A190422-","T190423-","A190424-","G190425-","C190426-","T190427-","A190428-","T190429-","T190430-","T190431-","A190432-","C190433-","G190434-","T190435-","A190436-","T190437-","T190438-","A190439-","G190440-","T190441-","A190442-","T190443-","C190444-","G190445-","G190446-","C190447-","A190448-","T190449-","C190450-","T190451-","C190452-","T190453-","T190454-","T190455-","T190456-","G190457-","T190458-","A190459-","T190460-","C190461-","T190462-","T190463-","G190464-","T190465-","T190466-","A190467-","A190468-","T190469-","T190470-","G190471-","T190472-","C190473-","A190474-","C190475-","A190476-","A190477-","A190478-","C190479-","T190480-","A190481-","G190482-","T190483-","A190484-","C190485-","A190486-","T190487-","T190488-","A190489-","C190490-","T190491-","T190492-","C190493-","A190494-","A190495-","T190496-","C190497-","T190498-","G190499-","A190500-","A190501-","A190502-","A190503-","T190504-","A190505-","A190506-","A190507-","T190508-","G190509-","G190510-","T197076G"],"OPG052":["A31T"]},"labels":{"aa":"OPG052: A31T"}},"children":[{"name":"NODE_0000031","node_attrs":{"div":297,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G36971A","G124667A","G125413A","G176109A"],"OPG055":["S38L"],"OPG145":["A241T"],"OPG146":["A76V"],"OPG205":["D152N"]},"labels":{"aa":"OPG055: S38L; OPG145: A241T; OPG146: A76V; OPG205: D152N"}},"children":[{"name":"JX878429","node_attrs":{"div":297,"accession":"JX878429","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0662"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-09-04"},"strain_display":{"value":"Democratic Republic of the Congo/JX878429/2007-09-04"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}},{"name":"JX878425","node_attrs":{"div":297,"accession":"JX878425","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0354"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-04-20"},"strain_display":{"value":"Democratic Republic of the Congo/JX878425/2007-04-20"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-144341G"]}}}]},{"name":"NODE_0000032","node_attrs":{"div":296,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["T18789C","G58263T","T73298C"],"OPG031":["T14A"]},"labels":{"aa":"OPG031: T14A"}},"children":[{"name":"JX878407","node_attrs":{"div":298,"accession":"JX878407","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 06-0950"},"host":{"value":"Homo sapiens"},"date":{"value":"2006-10-09"},"strain_display":{"value":"Democratic Republic of the Congo/JX878407/2006-10-09"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C15207T","C47598T"],"OPG025":["A21T"]},"labels":{"aa":"OPG025: A21T"}}},{"name":"NODE_0000033","node_attrs":{"div":297,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C15349A"]}},"children":[{"name":"JX878424","node_attrs":{"div":297,"accession":"JX878424","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0338"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-03-25"},"strain_display":{"value":"Democratic Republic of the Congo/JX878424/2007-03-25"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A179227G","A179236G"]}}},{"name":"JX878423","node_attrs":{"div":298,"accession":"JX878423","author":{"author":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G.","value":"Kugelman,J.R.,Johnston,S.C.,Mulembakani,P.M.,Kisalu,N.,Lee,M.S.,Koroleva,G.,McCarthy,S.E.,Gestole,M.C.,Wolfe,N.D.,Fair,J.N.,Schneider,B.S.,Wright,L.L.,Huggins,J.,Whitehouse,C.A.,Wemakoy,E.O.,Muyembe-Tamfum,J.J.,Hensley,L.E.,Palacios,G.F.,Rimoin,A.W.,Palacios,G."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Center for Genome Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), USA"},"strain":{"value":"DRC 07-0337"},"host":{"value":"Homo sapiens"},"date":{"value":"2007-03-25"},"strain_display":{"value":"Democratic Republic of the Congo/JX878423/2007-03-25"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C108244T"],"OPG127":["M194I"]},"labels":{"aa":"OPG127: M194I"}}}]}]}]},{"name":"NODE_0000034","node_attrs":{"div":291,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["A159953T","A179164-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","A179236G","T197076G"]}},"children":[{"name":"NODE_0000035","node_attrs":{"div":294,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C4584T","T55501C","A168328C","C179163T","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG074":["Y542C"],"OPG195":["K33N"]},"labels":{"aa":"OPG074: Y542C; OPG195: K33N"}},"children":[{"name":"MN702453","node_attrs":{"div":294,"accession":"MN702453","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702453"},"host":{"value":"Homo sapiens"},"date":{"value":"2001-08-11"},"strain_display":{"value":"Central African Republic/MN702453/2001-08-11"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}},{"name":"MN702452","node_attrs":{"div":295,"accession":"MN702452","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702452"},"host":{"value":"Homo sapiens"},"date":{"value":"2010-08-10"},"strain_display":{"value":"Central African Republic/MN702452/2010-08-10"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C164169T"]}}}]},{"name":"NODE_0000036","node_attrs":{"div":292,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G42564A","-179164G","-179172T"]}},"children":[{"name":"NODE_0000037","node_attrs":{"div":295,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["C6624-","G6625-","A6626-","G6627-","T6628-","A6629-","G6630-","T6631-","A6632-","A6633-","C6634-","T6635-","T6636-","C6637-","T6638-","A6639-","A6640-","T6641-","A6642-","A6643-","A6644-","G6645-","A6646-","C6647-","T6648-","T6649-","G6650-","A6651-","T6652-","A6653-","T6654-","C6655-","A6656-","T6657-","T6658-","A6659-","T6660-","C6661-","A6662-","T6663-","A6664-","T6665-","G6666-","T6667-","T6668-","T6669-","G6670-","A6671-","T6672-","C6673-","G6674-","T6675-","C6676-","A6677-","T6678-","A6679-","G6680-","T6681-","T6682-","A6683-","A6684-","T6685-","A6686-","G6687-","T6688-","G6689-","T6690-","G6691-","G6692-","C6693-","T6694-","A6695-","A6696-","A6697-","T6698-","G6699-","G6700-","T6701-","A6702-","C6703-","T6704-","G6705-","T6706-","T6707-","A6708-","A6709-","T6710-","A6711-","A6712-","G6713-","T6714-","T6715-","T6716-","A6717-","T6718-","A6719-","G6720-","A6721-","C6722-","A6723-","A6724-","T6725-","A6726-","T6727-","C6728-","A6729-","T6730-","A6731-","G6732-","T6733-","C6744-","A6745-","G6746-","A6747-","A6748-","T6749-","T6750-","A6751-","G6752-","A6753-","T6754-","T6755-","A6756-","T6757-","T6758-","T6759-","T6760-","T6761-","T6762-","T6763-","A6764-","A6765-","A6766-","T6767-","A6768-","C6769-","T6770-","G6771-","A6772-","T6773-","C6774-","C6775-","T6776-","C6777-","A6778-","C6779-","A6780-","A6781-","T6782-","T6783-","C6784-","C6785-","G6786-","T6787-","G6788-","A6789-","T6790-","G6791-","T6792-","A6793-","G6794-","C6795-","A6796-","G6797-","T6798-","A6799-","G6800-","T6801-","T6802-","G6803-","G6804-","T6805-","G6806-","C6807-","A6808-","T6809-","G6810-","G6811-","T6812-","C6813-","T6814-","A6815-","T6816-","A6817-","T6818-","C6819-","G6820-","T6821-","T6822-","A6823-","A6824-","A6825-","A6826-","T6827-","G6828-","A6835G","T6836G","G6843T","T6846G","C6848G","G6850-","A6851-","C6852-","G6853-","T6854-","G6855-","G6856-","A6857-","G6858-","T6859-","A6860-","C6861-","A6862-","G6863-","A6864-","A6865-","T6866-","T6867-","T6868-","T6869-","C6870-","G6871-","A6872-","T6873-","T6874-","A6875-","A6876-","T6877-","G6878-","A6879-","G6880-","T6881-","T6882-","C6883-","A6884-","T6885-","G6886-","G6887-","T6888-","A6889-","A6890-","G6891-","G6892-","A6893-","A6894-","G6895-","G6896-","G6897-","C6898-","A6899-","A6900-","A6901-","T6902-","G6903-","T6904-","A117317G","G150585-","G150620A","G150621A","A150634-","A150635-","A169721-","C169722-","A169723-","G169724-","A169725-","T169726-","G171695A","-173286A","-173287T","-173288A","-173289T","G174029A","-174537G","-174538A","-174539T","-174540G","-174541A","-174542A"],"OPG197":["T18-","D19-"]},"labels":{"aa":"OPG197: T18-, D19-"}},"children":[{"name":"MN702448","node_attrs":{"div":296,"accession":"MN702448","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702448"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-03-07"},"strain_display":{"value":"Central African Republic/MN702448/2018-03-07"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G168741A"],"OPG195":["R171K"]},"labels":{"aa":"OPG195: R171K"}}},{"name":"MN702447","node_attrs":{"div":295,"accession":"MN702447","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702447"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-03-20"},"strain_display":{"value":"Central African Republic/MN702447/2018-03-20"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000038","node_attrs":{"div":296,"clade_membership":{"value":"I"}},"branch_attrs":{"mutations":{"nuc":["G7410A","A146863-","T146864-","T146866-","G169138A","A171639T","G186880A"],"OPG199":["T218S"],"OPG210":["R1842H"]},"labels":{"aa":"OPG199: T218S; OPG210: R1842H"}},"children":[{"name":"MN702450","node_attrs":{"div":305,"accession":"MN702450","author":{"author":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A.","value":"Selekon,B.,Labouba,I.L.,Gonofio,E.C.,Sem Ouilibona,R.,Simo Tchetgna,H.,Besombes,C.,Feher,M.,Fontanet,A.,Kazanji,M.,Manugerra,J.-C.,Gessain,A.,Nakoune,E.,Berthet,N.,Nkili Meyong,A."},"country":{"value":"Central African Republic"},"institution":{"value":"Virology, Centre International de Recherches Medicales de Franceville, CIRMF, Gabon"},"strain":{"value":"MN702450"},"host":{"value":"Homo sapiens"},"date":{"value":"2016-01-01"},"strain_display":{"value":"Central African Republic/MN702450/2016-01-01"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C6388A","G8888A","C47932A","G100885T","G108940A","C122824A","T138194A","T146865-","T146867-","A146868-","T146869-","A146870-","T146871-","G172951T","A186911G"],"OPG128":["A39V"],"OPG143":["K164N"],"OPG155":["T100S"],"OPG210":["I1852M"]},"labels":{"aa":"OPG128: A39V; OPG143: K164N; OPG155: T100S; OPG210: I1852M"}}},{"name":"OQ729808","node_attrs":{"div":305,"accession":"OQ729808","author":{"author":"Lee,T.Y.,Hwang,Y.-H.,Yun,M.-R.,Kim,Y.-J.,Kim,D.","value":"Lee,T.Y.,Hwang,Y.-H.,Yun,M.-R.,Kim,Y.-J.,Kim,D."},"country":{"value":"Democratic Republic of the Congo"},"institution":{"value":"Korea National Institute of Health, Division of Infectious Disease Vaccine Research"},"strain":{"value":"MPXV/COD/2023/172V"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-XX-XX"},"strain_display":{"value":"Democratic Republic of the Congo/OQ729808/2022-XX-XX"},"clade_membership":{"value":"I"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A134C","C29763T","G45818A","G70364A","G111683A","C131908A","G133359A","G139736A","-146866G","T146877A","A146880T","T148344A","G179164A","T179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","G179236A","G188460A"],"OPG089":["D167N"],"OPG130":["P74S"],"OPG158":["R12C"]},"labels":{"aa":"OPG089: D167N; OPG130: P74S; OPG158: R12C"}}}]}]}]}]}]}]}]}]}]},{"name":"NODE_0000039","node_attrs":{"div":308,"clade_membership":{"value":"II"}},"branch_attrs":{"mutations":{"nuc":["C466T","A630C","C720T","G1093A","T1201C","G1504A","G2086T","A2391C","C2554T","G4836T","A5751G","G6076A","G6146A","T6904C","C7005T","C7648T","C7810T","G8066A","G8694T","C8923T","G9161T","G9376A","A9509T","A9698G","C10992T","G12003A","A12324C","G12352A","G12380A","G12418T","C13135T","A13223C","A13348G","C13995T","T13999G","T14091C","C14431T","A15602G","C15794T","G16393T","G16406A","A16581G","-16608G","G16634A","T17496C","C17800T","C18478A","C18953T","C19290T","C19392A","C19457T","G19475A","G20605A","G21034A","G21191A","T22928C","G23080T","-23171A","G24032A","C24179T","C25856T","C27614T","C27949T","T28532A","G28548A","T28710C","G31102A","A31144G","C32867T","A33102T","C33656A","C33708A","C34301A","G35613A","C36049T","T37170C","C39248T","G40558T","C40565T","T40937C","T41967C","A42516T","G42769A","C43751T","T44972A","G45500A","G45584A","A45637C","G46217A","C46417T","C46427A","T47140G","C47181T","T47735G","G49223T","T49994C","A50595C","G52354T","C52684T","C52938T","A52989C","G53156A","A53257G","C55188T","G55203A","C56531T","G58035T","C58131T","C58965T","G59046A","T59488C","G59709A","G60874C","C61056A","C62823T","C63156T","C63303T","A63976G","G64465A","A65352T","G65663A","G66263A","C66761A","C67245T","C67550T","T69675G","G72261A","G73076A","G75790A","C76123T","G76198A","G76648A","G76911A","C78461A","G78641A","G78942A","T79267C","A79502C","G79829A","T81989C","C83360T","C83843T","G84395A","T85763C","T86502G","T87584C","G88773A","G90493A","C90891T","G91347A","G91489T","C93356T","C95469T","T96651C","A97572G","A99234G","C100341T","A102971C","G103051A","G103424T","C106857A","G107511T","G108793A","G110828T","C111539T","G111545A","T111591A","A113747G","G114458A","C116583T","T116643A","A116660G","A117014G","G117725T","C118520T","A120174C","C120363T","G121082A","A121453C","G121711A","C122049T","A122422G","C124687T","A125047G","G125334A","G125556A","G126923T","C126969T","C127859T","G128546T","G130030A","C131806T","C132118T","C133280T","G133328A","G133455A","T134233A","G134491A","C134765T","G136190T","C136486A","G136596A","G137026T","C137377T","C137731T","G137925A","C138513T","A138654G","C138746T","G139285T","C139539T","G139771A","C139874T","G143108A","C143392T","T143997C","C144049T","C145074T","G145088T","C145336T","G145523T","C145551A","T146098G","G146215A","G146434A","T146446C","G147904T","T150132C","A150153G","C150488T","C150513T","G150545A","G150780A","G151320A","A151341C","G151923A","A152967T","G153645A","T154702C","T154975C","A155479C","G155843A","G158787T","G159351A","C159530T","T159741C","G159780A","T160924A","T161519A","T162639C","G162720A","A165006G","T165691C","C166934T","C168185T","C168588-","T168769C","A168987C","G169081A","C169142T","G169353A","-169721T","G169772-","C170037T","G170335A","A172087-","G172304A","G173102A","G173472A","T173569C","G173974A","A174301G","T175964C","T176453C","A176701G","A176715G","C177517T","C177724T","C178237T","C178311A","A178639G","A178791G","A179023G","T179478C","C179538A","T179589G","C179690T","C180197T","A181364T","C182033T","C182348A","G183491A","C183718T","C183920T","C184286T","A185268G","G185762A","C185900T","C186077T","G186466T","G186505A","C187345T","G187498A","C187839T","A187914G","C187964T","C188537T","A188726G","C188747A","G188812A","C189909A","A190154G","T190404G","G190596T","T190648A","G191051A","C191064T","A191401G","T191459C","C192374A","-192471C","T194819G","C195124A","C195706T","A196009G","C196117T","G196490A","G196744A"],"OPG002":["S121A"],"OPG002_dup":["S121A"],"OPG015":["A4V","F136L"],"OPG015_dup":["A4V","F136L"],"OPG016":["A63S","V80E"],"OPG021":["I38V"],"OPG023":["A174V","S193A","H300Y","E637K"],"OPG024":["G32S"],"OPG025":["K393E","V425I"],"OPG029":["R146C"],"OPG030":["D12N","N113S"],"OPG031":["E117D"],"OPG034":["R205L"],"OPG036":["P11S"],"OPG037":["R415C"],"OPG038":["P27H","I78V"],"OPG043":["A3T"],"OPG044":["L148M"],"OPG045":["T185A"],"OPG049":["V17E"],"OPG056":["Y622C"],"OPG059":["L26I"],"OPG063":["A307V"],"OPG064":["S88A"],"OPG065":["D23N"],"OPG066":["R83K","N97H"],"OPG068":["E341D"],"OPG071":["T428I","S484A","V501I"],"OPG074":["D199N"],"OPG079":["Y45C"],"OPG080":["E321D","S382C"],"OPG084":["T211S"],"OPG085":["A328T","V591F"],"OPG096":["M68I"],"OPG100":["Q152K"],"OPG101":["A153T"],"OPG102":["V249I"],"OPG109":["T622A"],"OPG111":["V77I"],"OPG112":["R34H"],"OPG130":["A122T"],"OPG135":["E90V"],"OPG145":["R463Q"],"OPG148":["S313I"],"OPG150":["E256D"],"OPG153":["H358Y","P493Q"],"OPG154":["R107H"],"OPG156":["S42Y","A222T"],"OPG157":["V24M"],"OPG159":["A2T","S36L"],"OPG164":["V111I"],"OPG165":["L161S"],"OPG167":["S107Y","V112I"],"OPG170":["I111M"],"OPG172":["D160Y"],"OPG176":["S227L"],"OPG178":["V139I"],"OPG185":["T205I"],"OPG187":["*300K"],"OPG195":["S120-"],"OPG197":["T18S"],"OPG198":["V100I"],"OPG200":["G52D"],"OPG205":["Y349C","S354G","A621V","A690V"],"OPG208":["T142I","A311V"],"OPG210":["L3F","N331K","A788V","T1305A","R1704L","G1717D"]},"labels":{"aa":"OPG002: S121A; OPG002_dup: S121A; OPG015: A4V, F136L; OPG015_dup: A4V, F136L; OPG016: A63S, V80E; OPG021: I38V; OPG023: A174V, S193A, H300Y, E637K; OPG024: G32S; OPG025: K393E, V425I; OPG029: R146C; OPG030: D12N, N113S; OPG031: E117D; OPG034: R205L; OPG036: P11S; OPG037: R415C; OPG038: P27H, I78V; OPG043: A3T; OPG044: L148M; OPG045: T185A; OPG049: V17E; OPG056: Y622C; OPG059: L26I; OPG063: A307V; OPG064: S88A; OPG065: D23N; OPG066: R83K, N97H; OPG068: E341D; OPG071: T428I, S484A, V501I; OPG074: D199N; OPG079: Y45C; OPG080: E321D, S382C; OPG084: T211S; OPG085: A328T, V591F; OPG096: M68I; OPG100: Q152K; OPG101: A153T; OPG102: V249I; OPG109: T622A; OPG111: V77I; OPG112: R34H; OPG130: A122T; OPG135: E90V; OPG145: R463Q; OPG148: S313I; OPG150: E256D; OPG153: H358Y, P493Q; OPG154: R107H; OPG156: S42Y, A222T; OPG157: V24M; OPG159: A2T, S36L; OPG164: V111I; OPG165: L161S; OPG167: S107Y, V112I; OPG170: I111M; OPG172: D160Y; OPG176: S227L; OPG178: V139I; OPG185: T205I; OPG187: *300K; OPG195: S120-; OPG197: T18S; OPG198: V100I; OPG200: G52D; OPG205: Y349C, S354G, A621V, A690V; OPG208: T142I, A311V; OPG210: L3F, N331K, A788V, T1305A, R1704L, G1717D","clade":"clade II"}},"children":[{"name":"NODE_0000040","node_attrs":{"div":395,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["G580T","C4693-","T6432G","A6448-","A6475-","A6481G","C6486G","A6494G","A6496G","T6521-","T6525A","A6529C","A6538G","C6547A","C6552T","G6557T","G6577A","A6597-","G6613A","A6620-","G6625-","C6647-","G6674T","G6687-","T6698-","C6703-","T6704-","C6722G","A6747-","T6758-","T6801A","G6810-","T6814G","A6823C","T6836-","C6852A","G6855-","T6874-","A6922-","A6959-","G6977-","G6979C","G6987-","G6992A","A7000-","C7014T","G7021T","C7024T","T7033A","A7041C","T7043G","A7052G","C7053A","A7059G","T7075C","G7078A","A7579-","C7864T","T8015C","A8143G","G8841A","T9054C","A11365G","C11745T","G12947A","C18109T","T19324A","A21111-","G22308A","C23190T","C23747T","G23966A","G24232-","C24233-","A24234-","C24977T","C25368-","C29203A","C30510T","G30699T","C31454A","G32326A","C35859T","C36732T","A42426G","A54013G","G55750A","G58482T","A70398C","G76393A","G77451A","C79658T","G80435T","G84373A","C85145T","A86916G","G87055A","C89607T","G89869A","G90034A","A91246-","A91247-","T91248-","G91249-","G91250-","A91251-","G91737A","G93422A","G94404T","G97371A","C99287T","G99587A","G100967A","A104985G","G106460T","G107366T","G125514T","T130846C","A131548G","T133086C","C133178-","C133182-","C133184-","C133539T","G133682A","G136446A","T136641C","A137515G","G140772A","G142337A","A146877-","T146878-","T146879-","T146880-","T146881-","A146882-","T146883-","A147926T","A148124G","C148542T","A150569-","T150570-","A150571-","T150572-","G150573-","A150574-","T150575-","G150576-","G150577-","A150578-","T150579-","A150580-","T150581-","G150582-","A150583-","T150584-","G150585-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G150603-","A150604-","T150605-","A150606-","T150607-","G150608-","A150609-","T150610-","G150611-","C153210A","G153894A","C156081T","C156162A","C156414-","G156448A","G156549-","C157280T","G157688-","C157689-","G157690-","G157693-","C158981T","G159964T","C160120T","G161760A","T166103-","T166104-","A166105-","A166106-","T166107-","A166108-","A166109-","T166110-","T166111-","A166112-","A166113-","T166114-","A166115-","A166116-","T168446-","A168447-","A169574G","A169763-","C169764-","A169765-","A169767-","-169772A","G169814-","A169815-","A169816-","G170283A","G170918-","G171068A","T172524C","T172667-","T173283-","A173284-","T173285-","G173318-","G173544A","G173641A","G175396A","A177073G","C178285T","T179072-","G179076-","C179423T","G181076A","C181117-","C181118-","C182411A","C182600T","C183466A","-187080T","G187398-","T187399-","A187400-","C187401-","C189273T","G192517-","C196630A","A197082G"],"OPG023":["D386N"],"OPG040":["E37D","A168T"],"OPG045":["E20D"],"OPG047":["L166I","D229N"],"OPG049":["P276S"],"OPG055":["A118T"],"OPG074":["S459F"],"OPG089":["E178A"],"OPG102":["H192Y"],"OPG105":["S1083N"],"OPG108":["A2V"],"OPG110":["V80I","A135T"],"OPG113":["A3T"],"OPG118":["A281V","G381D"],"OPG120":["A261V"],"OPG123":["V29A"],"OPG125":["H97N","L399I"],"OPG153":["T343A","I370-","I371-","H408Y"],"OPG163":["V46I"],"OPG172":["D167V"],"OPG173":["T30A"],"OPG174":["C285Y"],"OPG185":["T22I"],"OPG195":["Y73-","D74-","Q75-","C76-","T77-","E78-","P79-","H80-","D81-","F82-","I83-","I84-","T85-","D86-","T87-","Q88-","Q89-","T90-","R91-","L92-","G93-","S94-","S95-","H96-","T97-","Y98-","I99-","K100-","F101-","S102-","N103-","M104-","N105-","T106-","G107-","V108-","P109-","S110-","S111-","I112-","P113-","K114-","C115-","S116-","R117-","T118-","L119-","I121-","S122-","V123-","Y124-","C125-","D126-","Q127-","E128-","A129-","G130-","D131-","I132-","K133-","F134-","E135-","E136-","Y137-","T138-","Q139-","E140-","S141-","S142-","D143-","I144-","S145-","I146-","R147-","V148-","K149-","Y150-","D151-","S152-","S153-","C154-","I155-","D156-","Y157-","L158-","G159-","I160-","N161-","Q162-","S163-","F164-","M165-","N166-","E167-","C168-","I169-","R170-","R171-","I172-","T173-","T174-","W175-","D176-","R177-","E178-","S179-","C180-","V181-","R182-","I183-","D184-","T185-","Q186-","T187-","I188-","N189-","K190-","Y191-","L192-","K193-","S194-","C195-","T196-","N197-","T198-","K199-","F200-","D201-","R202-","N203-","V204-","Y205-","K206-","R207-","Y208-"],"OPG197":["D33-","D35N","E49-"],"OPG204":["E289K"],"OPG205":["H473R"],"OPG208":["T53I"],"OPG209":["G187R"],"OPG210":["S704Y"]},"labels":{"aa":"OPG023: D386N; OPG040: E37D, A168T; OPG045: E20D; OPG047: L166I, D229N; OPG049: P276S; OPG055: A118T; OPG074: S459F; OPG089: E178A; OPG102: H192Y; OPG105: S1083N; OPG108: A2V; OPG110: V80I, A135T; OPG113: A3T; OPG118: A281V, G381D; OPG120: A261V; OPG123: V29A; OPG125: H97N, L399I; OPG153: T343A, I370-, I371-, H408Y; OPG163: V46I; OPG172: D167V; OPG173: T30A; OPG174: C285Y; OPG185: T22I; OPG195: Y73-, D74-, Q75-, C76-, T77-, E78-, P79-, H80-, D81-, F82-, I83-, I84-, T85-, D86-, T87-, Q88-, Q89-, T90-, R91-, L92-, G93-, S94-, S95-, H96-, T97-, Y98-, I99-, K100-, F101-, S102-, N103-, M104-, N105-, T106-, G107-, V108-, P109-, S110-, S111-, I112-, P113-, K114-, C115-, S116-, R117-, T118-, L119-, I121-, S122-, V123-, Y124-, C125-, D126-, Q127-, E128-, A129-, G130-, D131-, I132-, K133-, F134-, E135-, E136-, Y137-, T138-, Q139-, E140-, S141-, S142-, D143-, I144-, S145-, I146-, R147-, V148-, K149-, Y150-, D151-, S152-, S153-, C154-, I155-, D156-, Y157-, L158-, G159-, I160-, N161-, Q162-, S163-, F164-, M165-, N166-, E167-, C168-, I169-, R170-, R171-, I172-, T173-, T174-, W175-, D176-, R177-, E178-, S179-, C180-, V181-, R182-, I183-, D184-, T185-, Q186-, T187-, I188-, N189-, K190-, Y191-, L192-, K193-, S194-, C195-, T196-, N197-, T198-, K199-, F200-, D201-, R202-, N203-, V204-, Y205-, K206-, R207-, Y208-; OPG197: D33-, D35N, E49-; OPG204: E289K; OPG205: H473R; OPG208: T53I; OPG209: G187R; OPG210: S704Y","clade":"clade IIa"}},"children":[{"name":"NODE_0000041","node_attrs":{"div":466,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["C334T","T602-","T603-","T604-","T605-","T606-","C3299A","T4722-","G4723-","A4724-","T4754-","G4755-","A4756-","C6423A","C6433T","C6436T","C6439T","-6448T","C6453A","-6475T","C6483A","C6505G","G6519T","-6521A","G6524T","T6580A","-6597T","A6601C","-6620G","-6625C","T6635A","T6641G","A6644G","-6647T","T6648A","G6650A","T6654A","C6661G","G6666T","T6667C","C6673A","T6675C","T6681C","-6687T","G6689A","-6698A","G6699A","A6702G","-6703T","-6704A","T6707G","A6709G","T6714A","T6715G","A6724G","T6725C","C6728G","-6747C","T6750A","T6754G","-6758G","A6764G","T6767G","G6771C","A6772T","C6777G","G6786A","T6792A","G6794A","G6797T","A6799T","G6800A","G6804A","-6810T","C6819T","T6822C","A6826G","T6829A","A6833C","T6834G","-6836G","T6838A","T6844C","G6853A","T6854G","-6855A","C6861G","A6865G","G6871C","-6874C","A6875T","T6881A","T6885C","A6894G","G6895A","A6899C","A6901T","A6911T","A6916T","A6918C","-6922T","A6923T","G6924-","A6930G","T6933G","T6946A","T6947A","T6952C","A6958G","-6959T","T6967G","T6969C","A6971T","T6972A","-6976G","-6977T","-6978T","G6983A","G6984T","-6987A","C6994T","C6995T","-7000C","T7003A","T7005G","A7009-","G7610A","T8335-","T10992C","C11237A","G12496T","G13465C","T16524C","G20501T","G22164A","C22169T","A23203G","A23289T","-25368A","A32972C","T33806C","T37110C","G40684T","T45966A","A45971-","T45972-","T45980-","T47499A","C50255T","G55330T","G64427A","C66773T","G71925A","C77775A","A78461C","A80583C","G83661A","A84278G","G88566T","C92630A","G103421A","C107921T","T108250C","C113843T","T125262C","G132531A","A133442G","C134489T","C135792T","-136558C","C136794T","G138298A","C141072T","G141294A","G144604A","T147634G","G150612-","A150613-","T150614-","A150615-","T150616-","G150617-","A150618-","T150619-","G150620-","G155105A","C155392T","T156215C","T156724-","G159963A","C160171T","G161470A","T162663G","A162722G","G163020T","C163836T","G165637T","T168345A","A168371-","C168372-","T168373-","G168374-","A168375-","T168376-","T168377-","G168378-","C168379-","A168380-","G168381-","T168382-","G168383-","T168384-","T168385-","C168386-","A168387-","T168388-","C168389-","G168390-","C168391-","C168392-","C168393-","A168394-","A168395-","C168396-","T168397-","G168398-","C168399-","A168400-","A168401-","G168402-","T168403-","G168404-","G168405-","A168406-","G168407-","G168408-","A168409-","T168410-","T168411-","G168412-","A168413-","T168414-","A168415-","A168416-","C168417-","T168418-","G168419-","A168420-","A168421-","G168422-","G168423-","C168424-","A168425-","A168426-","T168427-","G168428-","G168429-","A168430-","T168431-","T168432-","C168433-","A168434-","G168435-","A168436-","G168437-","T168438-","A168439-","G168440-","T168441-","T168442-","A168443-","T168444-","A168445-","T168448-","G168449-","A168450-","T168451-","C168452-","A168453-","A168454-","T168455-","G168456-","T168457-","A168458-","C168459-","A168460-","G168461-","A168462-","A168463-","C168464-","C168465-","C168466-","C168467-","A168468-","T168469-","G168470-","A168471-","C168472-","T168473-","T168474-","T168475-","A168476-","T168477-","T168478-","A168479-","T168480-","C168481-","A168482-","C168483-","C168484-","G168485-","A168486-","T168487-","A168488-","C168489-","T168490-","C168491-","A168492-","A168493-","C168494-","A168495-","A168496-","A168497-","C168498-","A168499-","C168500-","G168501-","T168502-","C168503-","T168504-","T168505-","G168506-","G168507-","A168508-","T168509-","C168510-","A168511-","T168512-","C168513-","T168514-","C168515-","A168516-","T168517-","A168518-","C168519-","A168520-","T168521-","A168522-","T168523-","A168524-","T168525-","T168526-","A168527-","A168528-","A168529-","T168530-","T168531-","C168532-","A168533-","G168534-","T168535-","A168536-","A168537-","C168538-","A168539-","T168540-","G168541-","A168542-","A168543-","T168544-","A168545-","C168546-","A168547-","G168548-","G168549-","T168550-","G168551-","T168552-","C168553-","C168554-","C168555-","A168556-","T168557-","C168558-","T168559-","A168560-","G168561-","T168562-","A168563-","T168564-","T168565-","C168566-","C168567-","A168568-","A168569-","A168570-","A168571-","T168572-","G168573-","T168574-","T168575-","C168576-","C168577-","A168578-","G168579-","A168580-","A168581-","C168582-","T168583-","C168584-","T168585-","C168586-","T168587-","T168589-","A168590-","T168591-","T168592-","T168593-","C168594-","T168595-","G168596-","T168597-","A168598-","T168599-","A168600-","T168601-","T168602-","G168603-","T168604-","G168605-","A168606-","T168607-","C168608-","A168609-","A168610-","G168611-","A168612-","G168613-","G168614-","C168615-","G168616-","G168617-","G168618-","A168619-","G168620-","A168621-","C168622-","A168623-","T168624-","A168625-","A168626-","A168627-","A168628-","T168629-","T168630-","T168631-","G168632-","A168633-","G168634-","G168635-","A168636-","G168637-","T168638-","A168639-","T168640-","A168641-","C168642-","T168643-","C168644-","A168645-","A168646-","G168647-","A168648-","A168649-","T168650-","C168651-","A168652-","A168653-","G168654-","T168655-","G168656-","A168657-","T168658-","A168659-","T168660-","C168661-","A168662-","G168663-","T168664-","A168665-","T168666-","T168667-","A168668-","G168669-","A168670-","G168671-","T168672-","T168673-","A168674-","A168675-","G168676-","T168677-","A168678-","T168679-","G168680-","A168681-","T168682-","T168683-","C168684-","A168685-","T168686-","C168687-","A168688-","T168689-","G168690-","T168691-","A168692-","T168693-","T168694-","G168695-","A168696-","T168697-","T168698-","A168699-","T168700-","C168701-","T168702-","G168703-","G168704-","G168705-","T168706-","A168707-","T168708-","T168709-","A168710-","A168711-","T168712-","C168713-","A168714-","A168715-","A168716-","G168717-","T168718-","T168719-","T168720-","C168721-","A168722-","T168723-","G168724-","A168725-","A168726-","T168727-","G168728-","A168729-","A168730-","T168731-","G168732-","T168733-","A168734-","T168735-","T168736-","C168737-","G168738-","A168739-","A168740-","G168741-","A168742-","A168743-","T168744-","T168745-","A168746-","C168747-","A168748-","A168749-","C168750-","A168751-","T168752-","G168753-","G168754-","G168755-","A168756-","T168757-","A168758-","G168759-","A168760-","G168761-","A168762-","A168763-","T168764-","C168765-","A168766-","T168767-","G168768-","C168769-","G168770-","T168771-","C168772-","A168773-","G168774-","A168775-","A168776-","T168777-","T168778-","G168779-","A168780-","T168781-","A168782-","C168783-","A168784-","C168785-","A168786-","G168787-","A168788-","C168789-","T168790-","A168791-","T168792-","A168793-","A168794-","A168795-","T168796-","A168797-","A168798-","A168799-","T168800-","A168801-","T168802-","C168803-","T168804-","T168805-","A168806-","A168807-","G168808-","T168809-","C168810-","T168811-","T168812-","G168813-","C168814-","A168815-","C168816-","C168817-","A168818-","A168819-","C168820-","A168821-","C168822-","A168823-","A168824-","A168825-","A168826-","T168827-","T168828-","C168829-","G168830-","A168831-","C168832-","C168833-","G168834-","T168835-","A168836-","A168837-","T168838-","G168839-","T168840-","C168841-","T168842-","A168843-","C168844-","A168845-","A168846-","A168847-","A168848-","G168849-","G168850-","T168851-","A168852-","C168945T","-169767T","T170754C","G172736A","C173569T","C174990T","C175537T","C178666T","-179072A","-179076T","C180258T","A180482-","T180483-","T180484-","A180485-","A180486-","A180487-","A180488-","A180489-","C181298T","T183552A","C187489T","G187888A","C188575T","C189627A","C192455-","A192456-","T192457-","C192487-","A192488-","T192489-","G193911T","A196610-","A196611-","A196612-","A196613-","A196614-","G196876A"],"OPG003":["D437Y"],"OPG003_dup":["D437Y"],"OPG019":["A11T"],"OPG023":["N135K","R555L","K637E"],"OPG025":["N601K"],"OPG037":["V89M"],"OPG039":["V277D"],"OPG052":["K64E"],"OPG074":["T599N"],"OPG083":["T97M"],"OPG085":["V587M"],"OPG099":["F37L"],"OPG100":["K152Q"],"OPG105":["V846I"],"OPG109":["D294E"],"OPG145":["M439T"],"OPG153":["A292T"],"OPG155":["T65I"],"OPG160":["M1I"],"OPG161":["A65T"],"OPG172":["S70A"],"OPG181":["A232T"],"OPG188":["N356K","Q376R"],"OPG195":["I39N","T48-","D49-","C50-","S51-","V52-","H53-","R54-","P55-","T56-","A57-","S58-","G59-","G60-","L61-","I62-","T63-","E64-","G65-","N66-","G67-","F68-","R69-","V70-","V71-","I72-"],"OPG197":["T32V"],"OPG204":["H336Y"],"OPG210":["L733I"]},"labels":{"aa":"OPG003: D437Y; OPG003_dup: D437Y; OPG019: A11T; OPG023: N135K, R555L, K637E; OPG025: N601K; OPG037: V89M; OPG039: V277D; OPG052: K64E; OPG074: T599N; OPG083: T97M; OPG085: V587M; OPG099: F37L; OPG100: K152Q; OPG105: V846I; OPG109: D294E; OPG145: M439T; OPG153: A292T; OPG155: T65I; OPG160: M1I; OPG161: A65T; OPG172: S70A; OPG181: A232T; OPG188: N356K, Q376R; OPG195: I39N, T48-, D49-, C50-, S51-, V52-, H53-, R54-, P55-, T56-, A57-, S58-, G59-, G60-, L61-, I62-, T63-, E64-, G65-, N66-, G67-, F68-, R69-, V70-, V71-, I72-; OPG197: T32V; OPG204: H336Y; OPG210: L733I"}},"children":[{"name":"MT903346","node_attrs":{"div":466,"accession":"MT903346","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"USA"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"strain":{"value":"MPXV-USA2003_099_Gambian_Rat"},"host":{"value":"Cricetomys gambianus"},"date":{"value":"2003-XX-XX"},"strain_display":{"value":"USA/MT903346/2003-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000042","node_attrs":{"div":467,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["-602T","C137626T","-196610A"]}},"children":[{"name":"MT903348","node_attrs":{"div":467,"accession":"MT903348","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"USA"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"strain":{"value":"MPXV-USA2003_099_Rope_Squirrel"},"host":{"value":"Funisciurus"},"date":{"value":"2003-XX-XX"},"strain_display":{"value":"USA/MT903348/2003-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"DQ011153","node_attrs":{"div":467,"accession":"DQ011153","author":{"author":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S.","value":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S."},"country":{"value":"USA"},"institution":{"value":"National Center for Infectious Diseases, Centers for Disease Control and Prevention (US CDC), USA"},"strain":{"value":"DQ011153"},"host":{"value":"Cynomys"},"date":{"value":"2003-XX-XX"},"strain_display":{"value":"USA/DQ011153/2003-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C49T"]}}},{"name":"MT903347","node_attrs":{"div":467,"accession":"MT903347","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"USA"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"strain":{"value":"MPXV-USA2003_099_Dormouse"},"host":{"value":"Gliridae"},"date":{"value":"2003-XX-XX"},"strain_display":{"value":"USA/MT903347/2003-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"DQ011157","node_attrs":{"div":467,"accession":"DQ011157","author":{"author":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S.","value":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S."},"country":{"value":"USA"},"institution":{"value":"National Center for Infectious Diseases, Centers for Disease Control and Prevention (US CDC), USA"},"strain":{"value":"DQ011157"},"host":{"value":"Homo sapiens"},"date":{"value":"2003-XX-XX"},"strain_display":{"value":"USA/DQ011157/2003-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000045","node_attrs":{"div":408,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["G707A","C2959T","G3843A","C5441A","T6581C","C6593-","-6597C","T6609G","A6651C","T6669G","A6679-","T6688C","-6698G","G6705-","T6706-","A6719C","T6737C","A6745-","G6746-","A6748-","T6749-","-6758A","T6761C","T6762C","A6768G","G6788-","T6802G","A6817C","-6836A","A6837G","T6869C","A6890C","A6913G","-6922C","T6939C","A6950C","A6951G","A6953C","T6957G","-6977A","-6978A","A6986-","G7186A","C13709T","T19165A","T28278C","T38382A","G47813T","G85661A","A85968G","A88560T","T97911C","C115877T","A136556-","T136557-","A136559-","T136560-","A136561-","T136562-","C136563-","T136570-","A161541-","-168588C","T170904-","G174537-","A174538-","T174539-","G174540-","A174541-","A174542-","T180475-","T180476-","A180477-","A180478-","A180479-","A180480-","A180481-","G191769T","C193367T","G194251A","C196503T"],"OPG003":["S550N"],"OPG003_dup":["S550N"],"OPG015":["W239L"],"OPG015_dup":["W239L"],"OPG025":["C520Y"],"OPG056":["D218V"],"OPG107":["K153E"],"OPG134":["A43V"],"OPG153":["E366-","D372-"]},"labels":{"aa":"OPG003: S550N; OPG003_dup: S550N; OPG015: W239L; OPG015_dup: W239L; OPG025: C520Y; OPG056: D218V; OPG107: K153E; OPG134: A43V; OPG153: E366-, D372-"}},"children":[{"name":"NODE_0000046","node_attrs":{"div":435,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["A2760-","A2761-","G3051A","A4691G","-4693C","-4694T","-4695T","C5809T","C6423A","C6433T","C6436T","C6439T","-6448T","C6453A","-6475T","C6483A","C6505G","G6519T","-6521A","G6524T","A6578T","T6579A","T6583A","T6586A","T6587A","G6591T","G6602C","G6608A","G6619A","-6620T","-6625T","T6638A","A6643T","-6647A","T6660A","-6687A","G6700A","G6713C","G6752T","T6763A","C6769A","C6775A","C6779T","C6784T","C6785A","G6791T","C6807A","-6810A","A6815T","G6828C","A6830T","G6843C","T6846A","-6855T","G6863A","C6870T","-6874G","T6877A","G6878C","G6880T","C6883A","G6887A","G6896T","T6934A","T6935A","A6938T","A6943T","-6959G","T6966A","-6976T","C6993T","C6999G","-7000T","A7004T","C7008T","T13272-","A13273-","A15512-","C15513-","G15514-","T15515-","C15516-","A15517-","A15518-","T15519-","G15520-","G15521-","T15522-","A15523-","C15524-","A15525-","A15526-","A15527-","T15528-","T15529-","T15530-","T15531-","A15532-","C19281T","G19891A","T20697C","T24732C","-25368A","G36310T","T38583C","T48389G","T62580A","C71655G","C79980T","T80764G","C87501T","C93701T","A95738G","C125798T","C133086T","T133087C","-133090T","G133115-","C145219A","A156894C","A164460T","C164835T","-169763A","-169764C","-169765A","-169767A","A169772G","-172087T","G178332T","-179072A","-179076T","T180075A","T180218C","A183473G","G191401A","-192515A","-192516A","-192517G","T192519C","C194159T","T194449-","T194450-"],"OPG034":["R39C"],"OPG036":["D123G"],"OPG044":["V63A"],"OPG056":["N151S"],"OPG091":["L96V"],"OPG102":["T299I"],"OPG104":["N86H"],"OPG147":["V64M"],"OPG197":["-33D","N35D"],"OPG208":["N270K","F318S"]},"labels":{"aa":"OPG034: R39C; OPG036: D123G; OPG044: V63A; OPG056: N151S; OPG091: L96V; OPG102: T299I; OPG104: N86H; OPG147: V64M; OPG197: -33D, N35D; OPG208: N270K, F318S"}},"children":[{"name":"KJ642616","node_attrs":{"div":454,"accession":"KJ642616","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"France"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"KJ642616"},"date":{"value":"1968-XX-XX"},"strain_display":{"value":"France/KJ642616/1968-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T580G","T19608C","T23228A","T24498A","G27605A","C29763T","C37493T","T56538G","A87055G","C102787T","C112599A","G119877A","G121660T","C125897T","G133059A","G133454A","-136561A","-136562T","-136563C","-136570A","T146884-","T146885-","T146886-","A146887-","T146888-","A146889-","T146890-","G150612-","A150613-","T150614-","A150615-","T150616-","G150617-","A150618-","T150619-","G150620-","C156438A","A157609C","C158379T","A160363-","G160364-","G163255A","G168753T","A196630C"],"OPG034":["Y133C"],"OPG040":["Q327H"],"OPG047":["D478N"],"OPG074":["K196N"],"OPG108":["V2A"],"OPG147":["A31T"],"OPG153":["-366D","-372D"]},"labels":{"aa":"OPG034: Y133C; OPG040: Q327H; OPG047: D478N; OPG074: K196N; OPG108: V2A; OPG147: A31T; OPG153: -366D, -372D"}}},{"name":"NODE_0000047","node_attrs":{"div":438,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["-607T","C7611A","C65892T","G116640A","C133521-","A136543-","T136544-","C136545-","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","T136571-","C136572-","G148317-","-196615A"],"OPG019":["A11D"],"OPG084":["P391S"],"OPG135":["S91L"],"OPG153":["D367-","D368-","D369-","D373-","D374-","D375-"]},"labels":{"aa":"OPG019: A11D; OPG084: P391S; OPG135: S91L; OPG153: D367-, D368-, D369-, D373-, D374-, D375-"}},"children":[{"name":"AY753185","node_attrs":{"div":442,"accession":"AY753185","author":{"author":"Chen,N.,Li,G.,Liszewski,M.K.,Atkinson,J.P.,Jahrling,P.B.,Feng,Z.,Schriewer,J.,Buck,C.,Wang,C.,Lefkowitz,E.J.,Esposito,J.J.,Harms,T.,Damon,I.K.,Roper,R.L.,Upton,C.,Buller,R.M.,Buller,R.M.L.","value":"Chen,N.,Li,G.,Liszewski,M.K.,Atkinson,J.P.,Jahrling,P.B.,Feng,Z.,Schriewer,J.,Buck,C.,Wang,C.,Lefkowitz,E.J.,Esposito,J.J.,Harms,T.,Damon,I.K.,Roper,R.L.,Upton,C.,Buller,R.M.,Buller,R.M.L."},"institution":{"value":"Biochemistry & Microbiology, University of Victoria, Canada"},"strain":{"value":"AY753185"},"date":{"value":"1958-XX-XX"},"strain_display":{"value":"nan/AY753185/1958-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G32868A","G50614A","C137466T","C170999T","A181253-"],"OPG049":["S95L"],"OPG070":["D9N"],"OPG153":["E68K"]},"labels":{"aa":"OPG049: S95L; OPG070: D9N; OPG153: E68K"}}},{"name":"AY603973","node_attrs":{"div":441,"accession":"AY603973","author":{"author":"Chen,N.,Li,G.,Liszewski,M.K.,Atkinson,J.P.,Jahrling,P.B.,Feng,Z.,Schriewer,J.,Buck,C.,Wang,C.,Lefkowitz,E.J.,Esposito,J.J.,Harms,T.,Damon,I.K.,Roper,R.L.,Upton,C.,Buller,R.M.,Buller,R.M.L.","value":"Chen,N.,Li,G.,Liszewski,M.K.,Atkinson,J.P.,Jahrling,P.B.,Feng,Z.,Schriewer,J.,Buck,C.,Wang,C.,Lefkowitz,E.J.,Esposito,J.J.,Harms,T.,Damon,I.K.,Roper,R.L.,Upton,C.,Buller,R.M.,Buller,R.M.L."},"institution":{"value":"Biochemistry & Microbiology, University of Victoria, Canada"},"strain":{"value":"AY603973"},"date":{"value":"1961-XX-XX"},"strain_display":{"value":"nan/AY603973/1961-XX-XX"},"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["G775A","G90845A","G92261A","A124807G","-146877A","-146878T","-146879T","-146880T","-146881T","-146882A","-146883T","A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","C196435T"],"OPG111":["S194N"]},"labels":{"aa":"OPG111: S194N"}}}]}]},{"name":"NODE_0000048","node_attrs":{"div":419,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["T4087G","A4864G","C6431T","G6432T","-6448A","A6451T","A6460-","-6475A","C6476G","C6478A","G6481A","T6485A","G6486A","C6489A","G6494T","C6498T","A6500T","C6501T","C6507T","A6515C","-6521T","A6528C","C6529A","T6534A","T6535A","G6538A","T6543C","G7927A","G10999A","T25369-","C25370-","C28393T","C43244T","T69852C","C133520T","G135371A","A150549T","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-150603G","-150604A","-150605T","-150606A","-150607T","-150608G","-150609A","-150610T","-150611G","T154017C","A163207-","A163208-","C163209-","T163210-","A163211-","A163212-","C163213-","T163214-","-169767T","T179068-","T179069-","A179070-","T179071-","T179073-","A179074-","T179075-","A179077-","T179078-","C190338T","T192346C","A193123C"],"OPG003":["E174A"],"OPG003_dup":["E174A"],"OPG040":["D37-"],"OPG063":["V149I"]},"labels":{"aa":"OPG003: E174A; OPG003_dup: E174A; OPG040: D37-; OPG063: V149I"}},"children":[{"name":"AY741551","node_attrs":{"div":453,"accession":"AY741551","author":{"author":"Chen,N.,Li,G.,Liszewski,M.K.,Atkinson,J.P.,Jahrling,P.B.,Feng,Z.,Schriewer,J.,Buck,C.,Wang,C.,Lefkowitz,E.J.,Esposito,J.J.,Harms,T.,Damon,I.K.,Roper,R.L.,Upton,C.,Buller,R.M.,Buller,R.M.L.","value":"Chen,N.,Li,G.,Liszewski,M.K.,Atkinson,J.P.,Jahrling,P.B.,Feng,Z.,Schriewer,J.,Buck,C.,Wang,C.,Lefkowitz,E.J.,Esposito,J.J.,Harms,T.,Damon,I.K.,Roper,R.L.,Upton,C.,Buller,R.M.,Buller,R.M.L."},"country":{"value":"Sierra Leone"},"institution":{"value":"Biochemistry & Microbiology, University of Victoria, Canada"},"strain":{"value":"Sierra Leone"},"date":{"value":"1970-XX-XX"},"strain_display":{"value":"Sierra Leone/AY741551/1970-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G2387A","G3432A","A4696-","A4697-","C4698-","T4699-","A4700-","A4701-","C4702-","T4703-","T4704-","A4705-","T4706-","G4707-","A4708-","C4709-","T4710-","T4711-","A4712-","A4713-","C4714-","T4715-","A4716-","A4717-","C4718-","T4719-","T4720-","A4721-","T4722-","G4723-","A4724-","C4725-","T4726-","T4727-","A4728-","A4729-","C4730-","T4731-","A4732-","A4733-","C4734-","T4735-","T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","A4748-","A4749-","C4750-","T4751-","T4752-","A4753-","T4754-","G4755-","A4756-","C4757-","T4758-","T4759-","A4760-","A4761-","C4762-","T4763-","A4764-","A4765-","C4766-","T4767-","T4768-","A4769-","T4770-","G4771-","A4772-","C4773-","T4774-","T4775-","G5777T","T6580A","C6581T","-6593C","C6597T","A6601C","G6609T","-6620G","-6625C","T6635A","T6641G","A6644G","-6647T","T6648A","G6650A","C6651A","T6654A","C6661G","G6666T","T6667C","G6669T","C6673A","T6675C","-6679A","T6681C","-6687T","C6688T","G6689A","G6698A","G6699A","A6702G","-6703T","-6704A","-6705G","-6706T","T6707G","A6709G","T6714A","T6715G","C6719A","A6724G","T6725C","C6728G","C6737T","-6745A","-6746G","-6747C","-6748A","-6749T","T6750A","T6754G","A6758G","C6761T","C6762T","A6764G","T6767G","G6768A","G6771C","A6772T","C6777G","G6786A","-6788G","T6792A","G6794A","G6797T","A6799T","G6800A","G6802T","G6804A","-6810T","C6817A","C6819T","T6822C","A6826G","T6829A","A6833C","T6834G","A6836G","G6837A","T6838A","T6844C","G6853A","T6854G","-6855A","C6861G","A6865G","C6869T","G6871C","-6874C","A6875T","T6881A","T6885C","C6890A","A6894G","G6895A","A6899C","A6901T","A6911T","G6913A","A6916T","A6918C","C6922T","A6923T","G6924-","A6930G","T6936C","C6939T","T6945G","C6950A","G6951A","C6953T","C6955T","G6957T","A6958T","-6959T","A6964C","A6965T","-6976A","A6977G","C6979G","T6981A","G6983A","-6986A","-6987G","T6989C","A6992G","C6994A","C6995G","-7000A","C7002A","T7003G","T7007A","C7010G","T7014A","C7016A","C7022G","T7024G","C7026A","A7033G","C7037G","C7041A","C7046T","C7050A","G7052A","A7053C","T7058A","G7059A","C7062G","G7063T","T7065G","C7068A","A7069G","C18480T","A21930G","C28278T","G28324A","C29640T","G79597A","C79729A","G84125A","C84980T","C89970T","G94626A","C94743T","G95525A","C110255T","G118298T","C123888A","G133545A","G134297T","C134622T","G134915A","-136570T","A152605T","C154167A","C154410T","A160211-","A160212-","C161917T","C163183-","T163184-","C163185-","T163186-","T163187-","T163188-","T163189-","T163190-","A163191-","A163192-","C163193-","T163194-","A163195-","A163196-","C163197-","T163198-","A163199-","A163200-","C163201-","T163202-","A163203-","A163204-","C163205-","T163206-","C163215-","T163216-","T163217-","A163218-","T163219-","G165759A","G172195A","C175461A","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","G180374A","A185597G","C188478T","C188879T","A189894G","C191433A","A192435-","A192436-","G192437-","T192438-","C192439-","A192440-","T192441-","A192442-","A192443-","G192444-","T192445-","T192446-","A192447-","G192448-","T192449-","T192450-","A192451-","A192452-","G192453-","T192454-","C192455-","A192456-","T192457-","A192458-","A192459-","G192460-","T192461-","T192462-","A192463-","G192464-","T192465-","T192466-","A192467-","A192468-","G192469-","T192470-","C192471-","A192472-","T192473-","A192474-","A192475-","G192476-","T192477-","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-","A192490-","A192491-","G192492-","T192493-","T192494-","A192495-","G192496-","T192497-","T192498-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","C193778T","C194823T","-196615A","-196616A","-196617A"],"OPG002":["S122L"],"OPG002_dup":["S122L"],"OPG015":["A127E"],"OPG015_dup":["A127E"],"OPG031":["D117N"],"OPG153":["-366E"],"OPG190":["S213N"],"OPG197":["T32V"],"OPG200":["G16R"]},"labels":{"aa":"OPG002: S122L; OPG002_dup: S122L; OPG015: A127E; OPG015_dup: A127E; OPG031: D117N; OPG153: -366E; OPG190: S213N; OPG197: T32V; OPG200: G16R"}}},{"name":"NODE_0000049","node_attrs":{"div":448,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["T600-","T601-","T602-","T603-","T604-","T605-","T606-","A6578T","T6579A","T6583A","T6586A","T6587A","G6591T","G6602C","G6608A","G6619A","-6620T","-6625T","T6638A","A6643T","-6647A","T6660A","-6687A","G6700A","G6713C","G6752T","T6763A","C6769A","C6775A","C6779T","C6784T","C6785A","G6791T","C6807A","-6810A","A6815T","G6828C","A6830T","G6843C","T6846A","-6855T","G6863A","C6870T","-6874G","T6877A","G6878C","G6880T","C6883A","G6887A","G6896T","T6934A","T6935A","A6938T","A6943T","-6959G","T6966A","-6976T","C6993T","C6999G","-7000T","A7004T","C7008T","G8774A","A8794G","G9698A","C15082T","C20362T","C33964T","C38427T","C45637T","C50494A","C50572T","C55215A","G72890T","A81454C","G93357A","G121527T","G125116A","C128093T","T132868C","G133163A","G133255A","G133428-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","T136571-","C136572-","A142508G","C150444A","-150569A","-150570T","-150571A","-150572T","-150573G","-150574A","-150575T","-150576G","-150577G","-150578A","-150579T","-150580A","-150581T","-150582G","-150583A","-150584T","-150585G","G151505T","C154806T","T156450A","G156637T","C160271G","A169757-","C169758-","A169759-","G169760-","A169761-","T169762-","C188457T","T189549C","A189726-","T189727-","T189728-","A196608-","A196609-","A196610-","A196611-","A196612-","A196613-","A196614-"],"OPG021":["V38I"],"OPG035":["G15S"],"OPG044":["V63A"],"OPG052":["R11Q"],"OPG056":["C203Y"],"OPG064":["A88T"],"OPG092":["Q20K"],"OPG105":["E110A"],"OPG113":["A543T"],"OPG140":["H74N"],"OPG153":["D367-","D368-","D369-"],"OPG163":["I103V"],"OPG181":["A132V"],"OPG197":["T30V","D31-","T32-"]},"labels":{"aa":"OPG021: V38I; OPG035: G15S; OPG044: V63A; OPG052: R11Q; OPG056: C203Y; OPG064: A88T; OPG092: Q20K; OPG105: E110A; OPG113: A543T; OPG140: H74N; OPG153: D367-, D368-, D369-; OPG163: I103V; OPG181: A132V; OPG197: T30V, D31-, T32-"}},"children":[{"name":"KP849470","node_attrs":{"div":464,"accession":"KP849470","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Yoshinori,N.,Muyembe,J.-J.,Kingbeni,P.M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Yoshinori,N.,Muyembe,J.-J.,Kingbeni,P.M."},"country":{"value":"C\u00f4te d'Ivoire"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"Cote d'Ivoire_1971"},"date":{"value":"1971-XX-XX"},"strain_display":{"value":"C\u00f4te d'Ivoire/KP849470/1971-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A9454-","C15863-","C15864-","T15865-","T50665-","C52231T","C65466T","T72702C","C72750T","A86790G","G105195A","A111561G","G116852A","A121165C","T134625G","T136553-","C136554-","G136573-","C141287T","C151475A","C162897T","-163207A","-163208A","-163209C","-163210T","-163211A","-163212A","-163213C","-163214T","T163407C","C167177T","A169751-","C169752-","A169753-","G169754-","A169755-","T169756-","A171862C"],"OPG070":["F26-"],"OPG092":["M66I"],"OPG197":["T28V","D29-","V30-"],"OPG199":["E292A"]},"labels":{"aa":"OPG070: F26-; OPG092: M66I; OPG197: T28V, D29-, V30-; OPG199: E292A"}}},{"name":"NODE_0000050","node_attrs":{"div":450,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["C7A","A14T","G19A","G21A","C23T","T38A","T51A","G54A","C60T","G66A","T68A","A79C","T88A","G8143T","A28532-","G156023A","A197122C","T197131G","A197142T","C197144T","G197150A","C197156T","A197159T","A197172T","T197182A","A197186C","T197192A","T197196A","G197203T"],"OPG044":["M148-"],"OPG153":["-372D"]},"labels":{"aa":"OPG044: M148-; OPG153: -372D"}},"children":[{"name":"DQ011156","node_attrs":{"div":452,"accession":"DQ011156","author":{"author":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S.","value":"Likos,A.M.,Sammons,S.A.,Olson,V.A.,Frace,A.M.,Li,Y.,Olsen-Rasmussen,M.,Davidson,W.,Galloway,R.,Khristova,M.L.,Reynolds,M.G.,Zhao,H.,Carroll,D.S.,Curns,A.,Formenty,P.,Esposito,J.J.,Regnery,R.L.,Damon,I.K.,Olsen-Rasmussen,M.S."},"country":{"value":"Liberia"},"institution":{"value":"National Center for Infectious Diseases, Centers for Disease Control and Prevention (US CDC), USA"},"strain":{"value":"DQ011156"},"host":{"value":"Homo sapiens"},"date":{"value":"1970-XX-XX"},"strain_display":{"value":"Liberia/DQ011156/1970-XX-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C39509T","G42709T","-179068T","-179069T","-179070A","-179071T","-179072A","-179073T","-179074A","-179075T","-179076T","-179077A","-179078T"],"OPG063":["T327K"]},"labels":{"aa":"OPG063: T327K"}}},{"name":"NODE_0000051","node_attrs":{"div":463,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["-600T","-601T","-602T","A2840C","A6577G","T6578A","A6579T","C6581A","A6583T","A6586T","A6587T","T6588A","A6590C","T6591G","-6593T","T6594A","C6597T","C6602G","G6607C","A6608G","G6609T","A6619G","T6620G","T6625C","T6635A","A6638T","T6641G","T6643A","A6644G","A6647T","T6648A","G6650A","C6651A","T6654A","A6660T","C6661G","G6666T","T6667C","G6669T","C6673A","T6675C","-6679A","T6681C","A6687T","C6688T","G6689A","G6698A","G6699A","A6700G","A6702G","-6703T","-6704A","-6705G","-6706T","T6707G","A6709G","C6713G","T6714A","T6715G","C6719A","A6724G","T6725C","C6728G","C6737T","-6745A","-6746G","-6747C","-6748A","-6749T","T6750A","T6752G","T6754G","A6758G","C6761T","C6762T","A6763T","A6764G","T6767G","G6768A","A6769C","G6771C","A6772T","A6775C","C6777G","T6779C","T6784C","A6785C","G6786A","-6788G","T6791G","T6792A","G6794A","G6797T","A6799T","G6800A","G6802T","G6804A","A6807C","A6810T","T6815A","C6817A","C6819T","T6822C","A6826G","C6828G","T6829A","T6830A","A6833C","T6834G","A6836G","G6837A","T6838A","C6843G","T6844C","A6846T","G6853A","T6854G","T6855A","C6861G","A6863G","A6865G","C6869T","T6870C","G6871C","G6874C","A6875T","A6877T","C6878G","T6880G","T6881A","A6883C","T6885C","A6887G","C6890A","A6894G","G6895A","T6896G","A6899C","A6901T","A6911T","G6913A","A6916T","A6918C","C6922T","A6923T","G6924-","A6930G","A6934T","A6935T","T6936C","T6938A","C6939T","T6943A","T6945G","C6950A","G6951A","C6953T","C6955T","G6957T","A6958T","G6959T","A6964C","A6965T","A6966T","A6978C","C6979G","G6983A","-6986A","-6987G","T6989C","A6992G","T6993C","C6994A","C6995G","G6999C","T7000A","C7002A","T7003G","T7004A","T7007A","T7008C","C7010G","T7014A","C7016A","C7022G","T7024G","C7026A","A7033G","C7037G","C7041A","C7046T","C7050A","G7052A","A7053C","T7058A","G7059A","C7062G","G7063T","T7065G","C7068A","A7069G","G10039A","C12561T","A15700-","G15701-","G46380A","A69837G","C89937A","C101011A","A116643G","G140316A","C159500A","T172828A","G187503T","G188419T","A190071-","T190072-","T194370G","-196608A","-196609A","-196610A"],"OPG023":["V114I"],"OPG065":["A35V"],"OPG135":["V90A"],"OPG185":["A195E"]},"labels":{"aa":"OPG023: V114I; OPG065: A35V; OPG135: V90A; OPG185: A195E"}},"children":[{"name":"KJ136820","node_attrs":{"div":467,"accession":"KJ136820","author":{"author":"Radonic,A.,Metzger,S.,Dabrowski,P.W.,Couacy-Hymann,E.,Schuenadel,L.,Kurth,A.,Matz-Rensing,K.,Boesch,C.,Leendertz,F.H.,Nitsche,A.","value":"Radonic,A.,Metzger,S.,Dabrowski,P.W.,Couacy-Hymann,E.,Schuenadel,L.,Kurth,A.,Matz-Rensing,K.,Boesch,C.,Leendertz,F.H.,Nitsche,A."},"country":{"value":"C\u00f4te d'Ivoire"},"institution":{"value":"Centre for Biological Security, Robert Koch Institute, Germany"},"strain":{"value":"KJ136820"},"host":{"value":"Platyrrhini"},"date":{"value":"2012-03-XX"},"strain_display":{"value":"C\u00f4te d'Ivoire/KJ136820/2012-03-XX"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C4538T","T16298C","G35634A","A167909C","-179068T","-179069T","-179070A","-179071T","-179072A","-179073T","-179074A","-179075T","-179076T","-179077A","-179078T","G192672A"],"OPG003":["D24N"],"OPG003_dup":["D24N"],"OPG027":["N27S"]},"labels":{"aa":"OPG003: D24N; OPG003_dup: D24N; OPG027: N27S"}}},{"name":"NODE_0000052","node_attrs":{"div":467,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["T4722-","G4723-","A4724-","C4725-","T4726-","T4727-","A4728-","A4729-","C4730-","T4731-","A4732-","A4733-","G4739A","C4741-","T4742-","T4743-","G21441A","A27251G","-28532A","-136559A","-136560T","-136561A","-136562T","-136563C","-136564A","-136565T","-136566C","-136567A","-136568T","-136569C","-136570A","-136571T","-136572C","-146877A","-146878T","-146879T","-146880T","-146881T","-146882A","-146883T","A150569-","T150570-","A150571-","T150572-","G150573-","A150574-","T150575-","G150576-","G150577-","A150578-","T150579-","A150580-","T150581-","G150582-","A150583-","T150584-","G150585-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-169757A","-169758C","-169759A","-169760G","-169761A","-169762T","-169763A","-169764C","-169765A","T169767A","A169772G","T179120-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","C186017T","A192467-","A192468-","G192469-","C192471T","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-"],"OPG044":["-148M"],"OPG153":["-366D","-367D","-368D","-369D"],"OPG197":["V30T","-31D","-32T","-33D","N35D"]},"labels":{"aa":"OPG044: -148M; OPG153: -366D, -367D, -368D, -369D; OPG197: V30T, -31D, -32T, -33D, N35D"}},"children":[{"name":"NODE_0000053","node_attrs":{"div":473,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["-603T","-604T","A4744-","A4745-","C4746-","T4747-","A4748-","A4749-","C4750-","T4751-","T4752-","A4753-","T4754-","G4755-","A4756-","C4757-","T4758-","T4759-","G57148A","C137932T","T145515-","C152375A","G155747T","G158403A","G177534T","T179183-","T179184-","A179185-","T179186-","-196611A","-196612A"],"OPG154":["G40E"],"OPG205":["D627Y"]},"labels":{"aa":"OPG154: G40E; OPG205: D627Y"}},"children":[{"name":"MN346702","node_attrs":{"div":473,"accession":"MN346702","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"strain":{"value":"MPXV_TNP_2018_East_Paddy"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2018-05-11"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346702/2018-05-11"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179121-"]}}},{"name":"MN346703","node_attrs":{"div":473,"accession":"MN346703","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"institution":{"value":"Robert Koch Institute, Project Group Epidemiology of Highly Pathogenic Microorganisms"},"strain":{"value":"MPXV_TNP_2018_East_Placali"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2018-05-20"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346703/2018-05-20"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-605T","-136556A","-136557T","-136558C","-179068A","-179069T","-179070A","-179071C","-179074A","-179075T","-179076T","-179077A","-179078T","-179120T","-179122A","-179123T","-179124A","-179125T","-179126A","-196613A"]}}}]},{"name":"NODE_0000054","node_attrs":{"div":472,"clade_membership":{"value":"IIa"}},"branch_attrs":{"mutations":{"nuc":["A22266-","T22267-","G22268-","A22269-","A22270-","G22271-","A22272-","A22273-","G22274-","T22275-","T22276-","C22277-","T22278-","T22279-","C22280-","T22281-","C44980T","C131652T","C133187-","A133188-","T133189-","T133190-","T133191-","C133192-","A133193-","T133194-","C133195-","C133196-","C133197-","C133198-","A133199-","T133200-","G133201-","C133202-","T133204A","T133749C","-136556A","-136557T","-136558C","C153524A","G156651T"],"OPG037":["E52-","E53-","L54-","L55-","H56-"],"OPG064":["D307N"],"OPG151":["T910I"],"OPG180":["T278K"]},"labels":{"aa":"OPG037: E52-, E53-, L54-, L55-, H56-; OPG064: D307N; OPG151: T910I; OPG180: T278K"}},"children":[{"name":"MN346700","node_attrs":{"div":472,"accession":"MN346700","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"strain":{"value":"MPXV_TNP_2017_South_Ravel_2"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-01-31"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346700/2017-01-31"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-22266A","-22267T","-22268G","-22269A","-22270A","-22271G","-22272A","-22273A","-22274G","-22275T","-22276T","-22277C","-22278T","-22279T","-22280C","-22281T","A136556-","T136557-","C136558-","T150549-","G150550-","G150551-","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","T150567-","G150568-","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179121-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-"],"OPG037":["-52E","-53E","-54L","-55L","-56H"]},"labels":{"aa":"OPG037: -52E, -53E, -54L, -55L, -56H"}}},{"name":"MN346699","node_attrs":{"div":472,"accession":"MN346699","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"strain":{"value":"MPXV_TNP_2017_South_Ravel_1"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-01-23"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346699/2017-01-23"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-22266A","-22267T","-22268G","-22269A","-22270A","-22271G","-22272A","-22273A","-22274G","-22275T","-22276T","-22277C","-22278T","-22279T","-22280C","-22281T","A136556-","T136557-","C136558-","T150549-","G150550-","G150551-","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","T150567-","G150568-","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179121-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-"],"OPG037":["-52E","-53E","-54L","-55L","-56H"]},"labels":{"aa":"OPG037: -52E, -53E, -54L, -55L, -56H"}}},{"name":"MN346701","node_attrs":{"div":472,"accession":"MN346701","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"institution":{"value":"Robert Koch Institute, Project Group Epidemiology of Highly Pathogenic Microorganisms"},"strain":{"value":"MPXV_TNP_2017_South_Woodstock"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-01-14"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346701/2017-01-14"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-603T","-604T","-605T","G610-","T611-","A6786G","G6788T","A6789C","G6791T","A6792T","A6793G","A6794G","A6796G","T6797G","T6799A","A6800G","A6801T","C6807A","T6810G","G6811A","G6814T","A6815C","T6819C","T6821A","C6822T","C6823A","T6922A","T6923A","-6924G","T6926G","T6933C","C6936G","C6940A","A6941T","G6945T","T6946A","T6947A","T6952C","T6953A","T6955C","T6958G","C6964A","T6965A","T6967G","T6969C","A6971T","T6972A","T6976G","A6977T","C6978T","G6979C","G6984T","G6987A","C6989T","G6992A","A6994T","G6995T","A7000C","A7002C","T7005G","A7007T","A7009-","G7010C","A7014T","A7016C","G7022C","G7024T","A7026C","G7033A","G7037C","A7041C","T7046C","A7050C","A7052G","C7053A","A7058T","A7059G","G7062C","T7063G","G7065T","A7068C","G7069A","-22266A","-22267T","-22268G","-22269A","-22270A","-22271G","-22272A","-22273A","-22274G","-22275T","-22276T","-22277C","-22278T","-22279T","-22280C","-22281T","A136556-","T136557-","C136558-","A136559-","T136560-","T150549-","G150550-","G150551-","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","T150567-","G150568-","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196611A"],"OPG037":["-52E","-53E","-54L","-55L","-56H"]},"labels":{"aa":"OPG037: -52E, -53E, -54L, -55L, -56H"}}},{"name":"MN346698","node_attrs":{"div":472,"accession":"MN346698","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"strain":{"value":"MPXV_TNP_2017_South_Pushkin"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-01-24"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346698/2017-01-24"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-22266A","-22267T","-22268G","-22269A","-22270A","-22271G","-22272A","-22273A","-22274G","-22275T","-22276T","-22277C","-22278T","-22279T","-22280C","-22281T","A136556-","T136557-","C136558-","T150549-","G150550-","G150551-","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","T150567-","G150568-","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179121-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-"],"OPG037":["-52E","-53E","-54L","-55L","-56H"]},"labels":{"aa":"OPG037: -52E, -53E, -54L, -55L, -56H"}}},{"name":"MN346697","node_attrs":{"div":472,"accession":"MN346697","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"institution":{"value":"Robert Koch Institute, Project Group Epidemiology of Highly Pathogenic Microorganisms"},"strain":{"value":"MPXV_TNP_2017_North_Surprise_2"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-04-14"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346697/2017-04-14"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A15924-","T15925-","T15926-","A15927-","A15928-","T15929-","C15930-","C15931-","A15932-","T15933-","G15934-","G15935-","A15936-","C15937-","T15938-","C15939-","A15940-","T15941-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-"]}}},{"name":"MN346696","node_attrs":{"div":472,"accession":"MN346696","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"strain":{"value":"MPXV_TNP_2017_North_Surprise_1"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-04-03"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346696/2017-04-03"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-179120T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A"]}}},{"name":"MN346695","node_attrs":{"div":472,"accession":"MN346695","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"strain":{"value":"MPXV_TNP_2017_North_Sidonie"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-04-02"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346695/2017-04-02"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T179183-"]}}},{"name":"MN346692","node_attrs":{"div":472,"accession":"MN346692","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"strain":{"value":"MPXV_TNP_2017_North_Mama"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-03-05"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346692/2017-03-05"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-179120T","-179122A","-179123T","-179124A","-179125T","-179126A","-179127C","-179128A","-179129T","-179130T","-179131A","-179132T","-179133A","-179134T","-179135A","-179136C","-179137A","-179138T","-179139T","-179140A","-179141T","-179142A","-179143T","-179144A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A"]}}},{"name":"MN346694","node_attrs":{"div":472,"accession":"MN346694","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"strain":{"value":"MPXV_TNP_2017_North_Saro"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-03-28"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346694/2017-03-28"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-179120T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A"]}}},{"name":"MN346690","node_attrs":{"div":472,"accession":"MN346690","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"institution":{"value":"Project Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Germany"},"strain":{"value":"MPXV_TNP_2017_North_Bic"},"host":{"value":"Pan troglodytes verus"},"date":{"value":"2017-03-13"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346690/2017-03-13"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-179139T","-179140A","-179141T","-179142A","-179143T","-179144A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A"]}}},{"name":"MN346691","node_attrs":{"div":472,"accession":"MN346691","author":{"author":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H.","value":"Patrono,L.V.,Pleh,K.,Samuni,L.,Ulrich,M.,Roethemeier,C.,Sachse,A.,Muschter,S.,Nitsche,A.,Couacy-Hymann,E.,Boesch,C.,Wittig,R.M.,Calvignac-Spencer,S.,Leendertz,F.H."},"country":{"value":"C\u00f4te d'Ivoire"},"institution":{"value":"Robert Koch Institute, Project Group Epidemiology of Highly Pathogenic Microorganisms"},"strain":{"value":"MPXV_TNP_2017_North_Environmental"},"date":{"value":"2017-03-11"},"strain_display":{"value":"C\u00f4te d'Ivoire/MN346691/2017-03-11"},"clade_membership":{"value":"IIa"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T7005G","A7007T","-179180A","-179181C","-179182A","-196611A"]}}}]}]}]}]}]}]}]}]},{"name":"NODE_0000055","node_attrs":{"div":474,"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C128T","G1687A","C1813A","G1814T","G3099T","G3420A","A4691G","-4694T","-4695T","-6976T","-6978C","G7950T","-8055A","T8286C","C8422T","-8499T","-8993T","C10267A","G10275A","T10641C","C11439T","G11593A","G11624A","G12712A","G12733A","G16788T","T18017A","A18861T","C19055T","T19304A","T20990A","G22575T","C24222T","G24358T","C24719G","G25173T","T25212G","G25407A","T25769G","A27215G","C28090A","T29446C","C29655T","T30500A","A31039G","A31793G","A32364G","C32477A","C33043T","-33199A","-33414T","C33963T","T34005C","G34295A","C34685T","A48148C","C51168T","C55805T","C58467T","C59256T","C67827T","G73821A","C74303G","C74382T","C78728A","A80756G","G81063A","T81182C","G81463T","T82838A","G84333A","C85163T","G86225A","G86535A","G87049A","C87501T","G87735A","C89214T","G89579T","G91023A","A92009G","G92102A","T92237C","A95477C","G95795A","G98430T","G99212A","G99683A","C99830T","C106115T","A107232G","T107394C","G109382A","A109580G","C111716T","T120252C","G120965A","C124737T","C124988G","G126255A","C132719A","-132813T","-133090T","-133091T","-133092T","-133093T","-133094T","-133095T","-133096T","-133097T","-133098T","-133099T","-133100T","-133101T","-133102T","-133177T","-133179T","-133180T","-133181T","-133183T","-133185A","-133186A","G133201A","C133733T","C133966T","G134884A","G135706A","G136498A","-136558G","G136604A","G136687A","G136870A","C143426T","C145803A","A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","C147860T","A148126G","T149765G","C150444T","T150756C","G154405A","-156415A","C156426T","G156512A","-156548A","G156954A","C156978T","T157273G","G157437A","C157490T","-157678A","-157679A","-157680A","-157681A","-157682T","-157683T","-157684T","-157685T","-157686A","-157687A","-157691A","-157692T","-157694A","-157695T","-157696A","-158027A","-158028T","-158029A","C158175A","G158398A","G158403A","G158511A","G158668T","G159415A","A159447C","C160152T","C161574T","G161799A","G162291A","C162828T","C163467T","C164848T","C165304T","G166399T","T167126C","C167858T","C168277A","-168588G","G169603A","G170248A","G170435A","-172087T","G172188A","G172980A","G173150A","-173286A","-173287T","-173288A","-173289T","-173290A","-173291T","-173292A","-173293T","-173294A","-173295T","-173296A","-173297T","-173298A","-173299T","-173300A","-173301T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","C173441T","-173501A","-173502T","-173745T","G173809A","C173810T","T173882C","C174170T","A175065C","C176160T","G177167T","C178275T","G178395A","G178540A","A178887G","-181114A","-181115T","-181116T","-181119T","-181120T","-181121A","-181122T","G181350A","G181994A","G182443A","G182491A","C183008T","G183695A","C183696T","G184137A","T187421C","C188096A","G189418A","-189744T","G189811T","G190098T","A190772C","-192515A","-192516A","T192519C","C193790T","C194111A","C195396A","G195397T","C195523T"],"OPG002":["T313N"],"OPG002_dup":["T313N"],"OPG005":["D74N"],"OPG016":["E121D"],"OPG019":["R124M"],"OPG021":["R230K"],"OPG022":["D73G"],"OPG023":["A426V","A488T"],"OPG031":["K271M"],"OPG036":["E25D"],"OPG040":["A254P","S374Y"],"OPG046":["N95S"],"OPG047":["K232I"],"OPG049":["V37M","M263T"],"OPG054":["G438R"],"OPG074":["V441I"],"OPG094":["T175R"],"OPG105":["G113V","V1070I"],"OPG108":["A4V"],"OPG118":["R256K","S413N","A462V"],"OPG125":["V514I"],"OPG130":["A63T"],"OPG145":["T264I","P348A"],"OPG153":["T355I"],"OPG164":["H217Y"],"OPG172":["T145M"],"OPG185":["A167T","E177D"],"OPG189":["R506C"],"OPG191":["C80F"],"OPG195":["-120C"],"OPG198":["D71N","R133Q"],"OPG204":["K178N"],"OPG205":["R169W"],"OPG210":["R363H","G379D","P781S","A928T"]},"labels":{"aa":"OPG002: T313N; OPG002_dup: T313N; OPG005: D74N; OPG016: E121D; OPG019: R124M; OPG021: R230K; OPG022: D73G; OPG023: A426V, A488T; OPG031: K271M; OPG036: E25D; OPG040: A254P, S374Y; OPG046: N95S; OPG047: K232I; OPG049: V37M, M263T; OPG054: G438R; OPG074: V441I; OPG094: T175R; OPG105: G113V, V1070I; OPG108: A4V; OPG118: R256K, S413N, A462V; OPG125: V514I; OPG130: A63T; OPG145: T264I, P348A; OPG153: T355I; OPG164: H217Y; OPG172: T145M; OPG185: A167T, E177D; OPG189: R506C; OPG191: C80F; OPG195: -120C; OPG198: D71N, R133Q; OPG204: K178N; OPG205: R169W; OPG210: R363H, G379D, P781S, A928T","clade":"clade IIb"}},"children":[{"name":"KJ642617","node_attrs":{"div":481,"accession":"KJ642617","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"Nigeria"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"KJ642617"},"date":{"value":"1971-XX-XX"},"strain_display":{"value":"Nigeria/KJ642617/1971-XX-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G13625A","G98489-","C98727T","T119718C","A129762G","-136555C","G149744A","G160174T","C160852T","A169769-","C169770-","A169771-","A169773-","T169774-","A181253-"],"OPG025":["T548M"],"OPG151":["D280G"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG025: T548M; OPG151: D280G; OPG197: T34-, D35-"}}},{"name":"NODE_0000056","node_attrs":{"div":500,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G3450A","C8893A","G18312A","C19367T","-32210A","-32211C","-32212G","C33143T","G38067A","G46895A","A48138G","C48527A","C53207A","G66580A","C80986T","T92516C","C100562T","T105126C","G128076A","C133145T","-136555T","G137627A","-140134A","-140135A","-140136C","-140137A","-140138A","-140139T","-140140T","-140141A","-140142T","G141300A","C141364T","C142450A","T146687C","A149878G","-158170A","G160867A","-166656T","-166657T","G167656T","-169772G","G171675A","-174531G","-174532A","-174533T","-174534G","-174535A","-174536A","G178423A","A179198-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","-187080T","C193760T","-196615A"],"OPG049":["-314R"],"OPG056":["A323V"],"OPG071":["W411L"],"OPG084":["R620Q"],"OPG104":["A12T"],"OPG150":["D100N"],"OPG153":["T14M"],"OPG159":["-124N","-125Y","-126N"],"OPG161":["E67K","A88V"],"OPG170":["D31G"],"OPG176":["N24D"],"OPG191":["-166F"],"OPG193":["R108I"],"OPG199":["E230K"]},"labels":{"aa":"OPG049: -314R; OPG056: A323V; OPG071: W411L; OPG084: R620Q; OPG104: A12T; OPG150: D100N; OPG153: T14M; OPG159: -124N, -125Y, -126N; OPG161: E67K, A88V; OPG170: D31G; OPG176: N24D; OPG191: -166F; OPG193: R108I; OPG199: E230K","clade":"A"}},"children":[{"name":"MK783031","node_attrs":{"div":504,"accession":"MK783031","author":{"author":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J.","value":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J."},"country":{"value":"Nigeria"},"institution":{"value":"NCEZID/DHCPP/PRB, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MK783031"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-11-09"},"strain_display":{"value":"Nigeria/MK783031/2017-11-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C5157T","G7764A","G9782A","G109736A","C133161T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","G192053A"],"OPG015":["D334N"],"OPG015_dup":["D334N"],"OPG019":["R62K"],"OPG021":["A66T"]},"labels":{"aa":"OPG015: D334N; OPG015_dup: D334N; OPG019: R62K; OPG021: A66T"}}},{"name":"NODE_0000057","node_attrs":{"div":504,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","G18769A","G81977A","G100261A","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","C154408T","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","-196616A","-196617A"],"OPG118":["E606K"]},"labels":{"aa":"OPG118: E606K"}},"children":[{"name":"OP535332","node_attrs":{"div":504,"accession":"OP535332","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2018_5232"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-01-XX"},"strain_display":{"value":"Nigeria/OP535332/2018-01-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C179199-","C179208-","C179217-"]}}},{"name":"NODE_0000058","node_attrs":{"div":505,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C28175T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T"]}},"children":[{"name":"NC_063383.1","node_attrs":{"div":505,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NC_063383","node_attrs":{"div":505,"accession":"NC_063383","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Senkevich,T.G.,Yutin,N.,Wolf,Y.I.,Koonin,E.V.,Moss,B.,Zmasek,C.M.,Knipe,D.M.,Pellett,P.E.,Scheuermann,R.H.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Senkevich,T.G.,Yutin,N.,Wolf,Y.I.,Koonin,E.V.,Moss,B.,Zmasek,C.M.,Knipe,D.M.,Pellett,P.E.,Scheuermann,R.H."},"country":{"value":"Nigeria"},"institution":{"value":"National Center for Biotechnology Information, NIH"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV-M5312_HM12_Rivers"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-08-XX"},"strain_display":{"value":"Nigeria/NC_063383/2018-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000059","node_attrs":{"div":503,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G51559A","C60923T","G179884A"],"OPG080":["E366K"],"OPG208":["E207K"]},"labels":{"aa":"OPG080: E366K; OPG208: E207K"}},"children":[{"name":"MT903337","node_attrs":{"div":505,"accession":"MT903337","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"Nigeria"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV-M2940_FCT"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-XX-XX"},"strain_display":{"value":"Nigeria/MT903337/2018-XX-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","G172784A","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","T181577C"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"OP535334","node_attrs":{"div":507,"accession":"OP535334","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2018_5223"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-02-XX"},"strain_display":{"value":"Nigeria/OP535334/2018-02-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T607-","C101683T","C127245T","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","G178814A","G178988A","C179199-","C179208-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A196615-"],"OPG149":["S17L"]},"labels":{"aa":"OPG149: S17L"}}},{"name":"OP535318","node_attrs":{"div":507,"accession":"OP535318","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2017_5227"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-12-XX"},"strain_display":{"value":"Nigeria/OP535318/2017-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-608T","C23311T","G75512A","G124715A","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","G162165A","C179199-","C179208-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","-196616A"],"OPG039":["E270K"],"OPG095":["R237K"],"OPG145":["D257N"]},"labels":{"aa":"OPG039: E270K; OPG095: R237K; OPG145: D257N"}}},{"name":"NODE_0000060","node_attrs":{"div":504,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A169769-","A169771-","A169773-","T169774-","G177009A","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","A196615-"],"OPG205":["E452K"]},"labels":{"aa":"OPG205: E452K"}},"children":[{"name":"OP535340","node_attrs":{"div":504,"accession":"OP535340","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2017_2888"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-10-XX"},"strain_display":{"value":"Nigeria/OP535340/2017-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C169770-","G169772-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"OP535326","node_attrs":{"div":509,"accession":"OP535326","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2018_5315"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-06-XX"},"strain_display":{"value":"Nigeria/OP535326/2018-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C23000T","G29826A","C109667T","A136552-","T136553-","C136554-","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","G147459A","G155644A","-169769A","-169771A","-169773A","-169774T","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"],"OPG038":["G54S"],"OPG047":["R457C"],"OPG153":["D385-"]},"labels":{"aa":"OPG038: G54S; OPG047: R457C; OPG153: D385-"}}}]}]},{"name":"NODE_0000061","node_attrs":{"div":506,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C8385T","G37209A","G43118A","G48180A","C113841T","A136552-","T136553-","C136554-","C146607T","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","T169721-","A169723-","A169725-","T169726-","A169727-","A169729-","A169731-","T169732-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-"],"OPG056":["S609F"],"OPG133":["G619E"],"OPG153":["D385-"],"OPG170":["E58K"]},"labels":{"aa":"OPG056: S609F; OPG133: G619E; OPG153: D385-; OPG170: E58K"}},"children":[{"name":"OP535328","node_attrs":{"div":506,"accession":"OP535328","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2018_5306"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-03-XX"},"strain_display":{"value":"Nigeria/OP535328/2018-03-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C169722-","G169724-","C169728-","G169730-","C179199-","C179208-","C179217-"],"OPG197":["S18-","D19-","T20-","D21-"]},"labels":{"aa":"OPG197: S18-, D19-, T20-, D21-"}}},{"name":"NODE_0000062","node_attrs":{"div":507,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G29889A","T76087-","A89106-","-169721T","-169723A","-169725A","-169726T","-169727A","-169729A","-169731A","-169732T","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T"],"OPG047":["P436S"]},"labels":{"aa":"OPG047: P436S"}},"children":[{"name":"NODE_0000063","node_attrs":{"div":510,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-","C40251T","C63801T","T121121-","G162243A","-196616A"],"OPG058":["D62N"],"OPG083":["E306K"]},"labels":{"aa":"OPG058: D62N; OPG083: E306K"}},"children":[{"name":"OP612684","node_attrs":{"div":513,"accession":"OP612684","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV/046/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-05-XX"},"strain_display":{"value":"Nigeria/OP612684/2019-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C92830T","A136543-","T136544-","C136545-","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","-173288A","-173289T","G180656A","G186423A","-196617A"],"OPG113":["S367F"],"OPG153":["D382-","D383-","D384-"],"OPG209":["D47N"],"OPG210":["E1690K"]},"labels":{"aa":"OPG113: S367F; OPG153: D382-, D383-, D384-; OPG209: D47N; OPG210: E1690K"}}},{"name":"OP612680","node_attrs":{"div":512,"accession":"OP612680","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV/021/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-04-01"},"strain_display":{"value":"Nigeria/OP612680/2019-04-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C63264T","-89106A","T104748C","T133098-","T133099-","T133100-","T133101-","T133102-","T187080-"],"OPG123":["D108G"]},"labels":{"aa":"OPG123: D108G"}}}]},{"name":"NODE_0000064","node_attrs":{"div":510,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","C28164T","C87027T","G121454A"],"OPG044":["S25F"]},"labels":{"aa":"OPG044: S25F"}},"children":[{"name":"OP612678","node_attrs":{"div":513,"accession":"OP612678","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV/017/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-03-14"},"strain_display":{"value":"Nigeria/OP612678/2019-03-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G46685A","G144659A","G165688A","T187080-","A196614-","A196615-"],"OPG167":["S250F"]},"labels":{"aa":"OPG167: S250F"}}},{"name":"NODE_0000065","node_attrs":{"div":512,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G3531A","-76087T","T151621G","T179068A","-196616A","-196617A"],"OPG178":["F38C"]},"labels":{"aa":"OPG178: F38C"}},"children":[{"name":"OP612675","node_attrs":{"div":513,"accession":"OP612675","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV/007/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-01-30"},"strain_display":{"value":"Nigeria/OP612675/2019-01-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T4676C","-89106A","-136552A","-136553T","-136554C","C193679T"]}}},{"name":"OP612676","node_attrs":{"div":512,"accession":"OP612676","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV/013/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-02-20"},"strain_display":{"value":"Nigeria/OP612676/2019-02-20"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A19360-","A23252-","T133100-","T133101-","T133102-","A138474-","A156769-","T163332-","A173514-","A173515-","G173516-","A173517-","A173518-","G173519-","A173520-","C173521-","G173522-","A173523-","G173524-","G173525-","A173526-","C173527-","G173528-","G173529-","A173530-","G173531-","A173532-","C173533-","G173534-","G173535-","T173536-","A173537-","G173538-","A173539-","A173540-","T173541-","A173542-","A173543-","T179072A"]}}}]}]}]}]},{"name":"NODE_0000066","node_attrs":{"div":501,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G154015A"],"OPG180":["D442N"]},"labels":{"aa":"OPG180: D442N"}},"children":[{"name":"OP535320","node_attrs":{"div":507,"accession":"OP535320","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2017_3008"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-11-XX"},"strain_display":{"value":"Nigeria/OP535320/2017-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-608T","C10430T","G15876A","C18699T","C143669T","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","G180039A","G189317A"],"OPG005":["R40K"],"OPG031":["D44N"],"OPG165":["L52F"],"OPG197":["T34-","D35-"],"OPG208":["M258I"]},"labels":{"aa":"OPG005: R40K; OPG031: D44N; OPG165: L52F; OPG197: T34-, D35-; OPG208: M258I"}}},{"name":"NODE_0000067","node_attrs":{"div":516,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-","C13298T","C18792T","C30636T","C34472T","C34578T","G80099A","G93387A","G114659A","G124031A","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","C148529-","A148530-","T148531-","A148532-","T148533-","C148534-","A148535-","G149265A","C149872T","C161953T","C165782T","G168205A","C177720T","A179194-","T179195-","A179196-","T179197-","C179199-","C179208-","A196614-","A196615-"],"OPG031":["D13N"],"OPG047":["D187N"],"OPG053":["G38E"],"OPG113":["E553K"],"OPG145":["D29N"],"OPG153":["D383-","D384-","D385-"],"OPG174":["S44L","D288-","M289-"],"OPG176":["Q22*"],"OPG188":["H120Y"],"OPG190":["P221S"],"OPG205":["R689C"]},"labels":{"aa":"OPG031: D13N; OPG047: D187N; OPG053: G38E; OPG113: E553K; OPG145: D29N; OPG153: D383-, D384-, D385-; OPG174: S44L, D288-, M289-; OPG176: Q22*; OPG188: H120Y; OPG190: P221S; OPG205: R689C","clade":"A.2"}},"children":[{"name":"ON675438","node_attrs":{"div":538,"accession":"ON675438","author":{"author":"Gigante,C.M.,Griffin-Thomas,L.A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Crain,J.,Li,Y.","value":"Gigante,C.M.,Griffin-Thomas,L.A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Crain,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2"},"strain":{"value":"MPXV_USA_2022_VA001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/ON675438/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-606T","-607T","G11332A","G12099A","C13648T","C15105T","C16227T","C29887T","C42101T","G64216A","G75614A","C117119T","C128534T","G130454A","C134442T","C142918T","G144446A","C156429T","C164832T","C168532T","G174610A","A175231-","T175232-","C175233-","G175234-","T175235-","A175236-","G175237-","T175238-","A175239-","T175240-","C175241-","A175242-","A175243-","G175244-","A175245-","T175246-","G175247-","T175248-","A175249-","A175250-","A175251-","A175252-","T175253-","A175254-","C175255-","T175256-","T175257-","A175258-","C175259-","G175260-","G175261-","T175262-","T175263-","A175264-","T175265-","A175266-","C175267-","C175268-","G175269-","T175270-","C175271-","A175272-","C175273-","A175274-","A175275-","G175276-","A175277-","C175278-","C175279-","A175280-","C175281-","A175282-","G175283-","G175284-","T175285-","T175286-","T175287-","A175288-","A175289-","A175290-","C175291-","T175292-","A175293-","A175294-","T175295-","A175296-","C175297-","T175298-","A175299-","G175300-","A175301-","T175302-","C175303-","C175304-","G175305-","A175306-","A175307-","A175308-","A175309-","T175310-","C175311-","A175312-","A175313-","C175314-","G175315-","T175316-","A175317-","A175318-","C175319-","G175320-","A175321-","T175322-","A175323-","G175324-","G175325-","A175326-","G175327-","A175328-","A175329-","C175330-","C175331-","T175332-","G175333-","C175334-","C175335-","A175336-","A175337-","T175338-","A175339-","T175340-","A175341-","A175342-","C175343-","A175344-","T175345-","G175346-","C175347-","A175348-","G175349-","T175350-","G175351-","C175352-","T175353-","G175354-","T175355-","G175356-","T175357-","C175358-","A175359-","A175360-","C175361-","G175362-","T175363-","C175364-","A175365-","T175366-","T175367-","A175368-","T175369-","T175370-","T175371-","G175372-","T175373-","C175374-","G175375-","A175376-","C175377-","G175378-","A175379-","T175380-","G175381-","T175382-","A175383-","C175384-","T175385-","G175386-","A175387-","T175388-","T175389-","G175390-","A175391-","A175392-","T175393-","G175394-","G175395-","G175396-","A175397-","A175398-","A175399-","A175400-","T175401-","C175402-","C175403-","A175404-","T175405-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A179628G","C179853T","G188544A","-196614A"],"OPG023":["R268*"],"OPG025":["D55N","M540I"],"OPG027":["D51N"],"OPG062":["S52L"],"OPG096":["D10N"],"OPG151":["E511K"],"OPG166":["D17N"],"OPG204":["E27K","I234-","V235-","V236-","S237-","R238-","C239-","K240-","I241-","L242-","T243-","V244-","I245-","P246-","S247-","Q248-","D249-","H250-","R251-","F252-","K253-","L254-","I255-","L256-","D257-","P258-","K259-","I260-","N261-","V262-","T263-","I264-","G265-","E266-","P267-","A268-","N269-","I270-","T271-","C272-","S273-","A274-","V275-","S276-","T277-","S278-","L279-","F280-","V281-","D282-","D283-","V284-","L285-","I286-","E287-","W288-","E289-","N290-","P291-","S292-"]},"labels":{"aa":"OPG023: R268*; OPG025: D55N, M540I; OPG027: D51N; OPG062: S52L; OPG096: D10N; OPG151: E511K; OPG166: D17N; OPG204: E27K, I234-, V235-, V236-, S237-, R238-, C239-, K240-, I241-, L242-, T243-, V244-, I245-, P246-, S247-, Q248-, D249-, H250-, R251-, F252-, K253-, L254-, I255-, L256-, D257-, P258-, K259-, I260-, N261-, V262-, T263-, I264-, G265-, E266-, P267-, A268-, N269-, I270-, T271-, C272-, S273-, A274-, V275-, S276-, T277-, S278-, L279-, F280-, V281-, D282-, D283-, V284-, L285-, I286-, E287-, W288-, E289-, N290-, P291-, S292-"}}},{"name":"OP612689","node_attrs":{"div":517,"accession":"OP612689","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2"},"strain":{"value":"MPXV/111/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-12-17"},"strain_display":{"value":"Nigeria/OP612689/2019-12-17"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G144876A","G173355-","A173356-","G173357-","G173358-","T173359-","A173360-","C173361-","G173362-","G173363-","G173364-","A173365-","T173366-","A173367-","G173368-","A173369-","A173370-","T173371-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A"],"OPG167":["P178S"]},"labels":{"aa":"OPG167: P178S"}}},{"name":"NODE_0000068","node_attrs":{"div":531,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G2752A","G39173A","C57284T","G61844A","C74226T","G118739A","C146223T","G148427A","G150800A","G168365A","G170317A","G172527A","C175759T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G189417A","C189474T","C194458T"],"OPG075":["R72K"],"OPG170":["D186N"],"OPG195":["E46K"],"OPG198":["D94N"],"OPG205":["A35V"]},"labels":{"aa":"OPG075: R72K; OPG170: D186N; OPG195: E46K; OPG198: D94N; OPG205: A35V","clade":"A.2.3"}},"children":[{"name":"ON676707","node_attrs":{"div":534,"accession":"ON676707","author":{"author":"Gigante,C.M.,Stringer,J.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Schulte,J.,Li,Y.","value":"Gigante,C.M.,Stringer,J.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Schulte,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.3"},"strain":{"value":"MPXV_USA_2021_TX"},"host":{"value":"Homo sapiens"},"date":{"value":"2021-07-XX"},"strain_display":{"value":"USA/ON676707/2021-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-606T","C100640T","G142636A","C186104T","-196614A"]}}},{"name":"OP555515","node_attrs":{"div":544,"accession":"OP555515","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.3"},"strain":{"value":"Monkeypox/PT0428/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Portugal/OP555515/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C30669T","C45028T","G49377A","G95355A","C121320T","G136132A","-136546A","-136547T","-136548C","G142265A","C159143T","C162264T","C170573T","C180686T","C181216T","G188229A"],"OPG047":["E176K"],"OPG064":["E291K"],"OPG068":["D393N"],"OPG139":["A17T"],"OPG153":["-383D"],"OPG163":["D22N"],"OPG185":["S76F"],"OPG198":["S179L"],"OPG209":["Q57*"]},"labels":{"aa":"OPG047: E176K; OPG064: E291K; OPG068: D393N; OPG139: A17T; OPG153: -383D; OPG163: D22N; OPG185: S76F; OPG198: S179L; OPG209: Q57*"}}}]},{"name":"NODE_0000069","node_attrs":{"div":536,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G11948A","C14790T","G21991A","G23118A","G38923A","G39515A","G56546A","G57786A","G93312A","C103019T","C112470T","C124129T","C127906T","G135303A","G145902A","C149365T","G155611A","G158424A","G162640A","G186984A"],"OPG023":["S318F"],"OPG025":["D160N"],"OPG037":["S148L"],"OPG056":["R38C"],"OPG113":["V528I"],"OPG122":["H198Y"],"OPG132":["M357I"],"OPG150":["S43L"],"OPG153":["D382-"],"OPG174":["G11R"],"OPG188":["G349S"],"OPG210":["D1877N"]},"labels":{"aa":"OPG023: S318F; OPG025: D160N; OPG037: S148L; OPG056: R38C; OPG113: V528I; OPG122: H198Y; OPG132: M357I; OPG150: S43L; OPG153: D382-; OPG174: G11R; OPG188: G349S; OPG210: D1877N","clade":"A.2.2"}},"children":[{"name":"OP422632","node_attrs":{"div":540,"accession":"OP422632","author":{"author":"Martin,F.,Anges,Y.,Benjamin,H.,Amadou,S.A.,Ousmane,F.","value":"Martin,F.,Anges,Y.,Benjamin,H.,Amadou,S.A.,Ousmane,F."},"country":{"value":"Benin"},"institution":{"value":"Institut Pasteur de Dakar, Virology Department"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.2"},"strain":{"value":"MPXV-SEN0022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Benin/OP422632/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T4619C","C4623-","T4624-","T4625-","T4626-","T4627-","T4628-","C4629-","A4630-","T4631-","A4632-","A4633-","T4634-","T4635-","A4636-","G4637-","A4638-","G4639-","A4640-","A4641-","A4642-","A4643-","A4644-","G4645-","A4646-","T4647-","C4648-","A4649-","A4650-","G4651-","G4652-","T4653-","A4654-","T4655-","A4656-","A4657-","A4658-","A4659-","A4660-","T4661-","T4662-","A4663-","G4664-","A4665-","A4666-","G4667-","T4668-","G4669-","T4670-","T4671-","A4672-","G4673-","A4674-","C4675-","T4676-","A4677-","T4678-","A4679-","A4680-","C32643T","-136546A","-136547T","-136548C","-136549A","-136550T","-136551C","-136552A","-136553T","-136554C","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","G146913-","T146914-","A146915-","-148529C","-148530A","-148531T","-148532A","-148533T","-148534C","-148535A","C156429T","G172501A","T196689-"],"OPG049":["R170K"],"OPG153":["-382D","-383D","-384D","-385D"],"OPG174":["-288D","-289M"],"OPG200":["E118K"]},"labels":{"aa":"OPG049: R170K; OPG153: -382D, -383D, -384D, -385D; OPG174: -288D, -289M; OPG200: E118K"}}},{"name":"OP450997","node_attrs":{"div":543,"accession":"OP450997","author":{"author":"Gigante,C.M.,Xia,D.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y.","value":"Gigante,C.M.,Xia,D.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.2"},"strain":{"value":"MPXV_USA_2022_PA0016"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OP450997/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G451A","G20576A","C20581T","G67351A","G78259A","G94479A","C133402T","A136543-","T136544-","C136545-","C176148T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C196759T"],"OPG036":["E162K"],"OPG085":["S394F"],"OPG205":["H165Y"]},"labels":{"aa":"OPG036: E162K; OPG085: S394F; OPG205: H165Y"}}},{"name":"NODE_0000070","node_attrs":{"div":541,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C13686T","C21861T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G151112A","G174721A","-179212A","-179213T","-179214A","-179215T","-179216A","C188491T"],"OPG025":["E528K"],"OPG037":["M191I"],"OPG204":["A64T"]},"labels":{"aa":"OPG025: E528K; OPG037: M191I; OPG204: A64T"}},"children":[{"name":"OP331336","node_attrs":{"div":545,"accession":"OP331336","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.2"},"strain":{"value":"MPXV_UK_2022_9000166"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-29"},"strain_display":{"value":"United Kingdom/OP331336/2022-06-29"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C27826T","G59282A","C65743A","G85356A","A136543-","T136544-","C136545-"],"OPG043":["E44K"],"OPG084":["P341H"],"OPG106":["S48F"]},"labels":{"aa":"OPG043: E44K; OPG084: P341H; OPG106: S48F"}}},{"name":"OR113690","node_attrs":{"div":551,"accession":"OR113690","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"country":{"value":"Austria"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.2"},"strain":{"value":"hMPXV/Austria/MUW1607960/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-04-05"},"strain_display":{"value":"Austria/OR113690/2023-04-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C18102T","C52429T","C86957T","G97318A","C121394T","G129982A","-136546A","-136547T","-136548C","-136549A","-136552A","-136553T","-136554C","G146714A","C148895A","G165892A","G175471A"],"OPG031":["D243N"],"OPG108":["D35N"],"OPG117":["D424N"],"OPG170":["A22V"],"OPG174":["M167I"],"OPG204":["E314K"]},"labels":{"aa":"OPG031: D243N; OPG108: D35N; OPG117: D424N; OPG170: A22V; OPG174: M167I; OPG204: E314K"}}}]}]},{"name":"NODE_0000071","node_attrs":{"div":517,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-606T","-607T","-608T","C25072T","A136543-","T136544-","C136545-","-179212A","-179213T","-179214A","-179215T","-179216A"],"OPG040":["R136Q"],"OPG153":["D382-"]},"labels":{"aa":"OPG040: R136Q; OPG153: D382-"}},"children":[{"name":"OP612691","node_attrs":{"div":519,"accession":"OP612691","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2"},"strain":{"value":"MPXV/191/20"},"host":{"value":"Homo sapiens"},"date":{"value":"2020-01-XX"},"strain_display":{"value":"Nigeria/OP612691/2020-01-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-609T","C90329T","C132520T","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG111":["S22L"]},"labels":{"aa":"OPG111: S22L"}}},{"name":"NODE_0000072","node_attrs":{"div":530,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G36898A","G42183A","C42903T","G50346A","C54268T","C73616T","G79406A","G105746A","A140492C","C142498T","C157737T","C161152T","A169763-","C169764-","A169765-","G169766-","A169767-","T169768-","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","C179537T","-196614A","-196615A"],"OPG062":["M79I"],"OPG063":["M262I"],"OPG069":["D121N"],"OPG102":["D108N"],"OPG160":["S195A"],"OPG197":["T32-","D33-","T34-","D35-"],"OPG208":["S91L"]},"labels":{"aa":"OPG062: M79I; OPG063: M262I; OPG069: D121N; OPG102: D108N; OPG160: S195A; OPG197: T32-, D33-, T34-, D35-; OPG208: S91L","clade":"A.2.1"}},"children":[{"name":"NODE_0000073","node_attrs":{"div":531,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T95936A"],"OPG116":["D192E"]},"labels":{"aa":"OPG116: D192E"}},"children":[{"name":"ON674051","node_attrs":{"div":533,"accession":"ON674051","author":{"author":"Gigante,C.M.,Lee,P.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"strain":{"value":"MPXV_USA_2022_FL001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/ON674051/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T608-","C112544T","G163540A"],"OPG132":["D333N"],"OPG189":["E70K"]},"labels":{"aa":"OPG132: D333N; OPG189: E70K"}}},{"name":"OR459777","node_attrs":{"div":539,"accession":"OR459777","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"country":{"value":"South Korea"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"strain":{"value":"MPXV-ROK-P004-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-22"},"strain_display":{"value":"South Korea/OR459777/2022-11-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["-609T","A46522G","G52289A","G67261A","C72231T","C115379T","C135822T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G181947A","G182189A","-196616A","-196617A"],"OPG071":["T717I"],"OPG085":["S424L"],"OPG210":["D198N"]},"labels":{"aa":"OPG071: T717I; OPG085: S424L; OPG210: D198N"}}}]},{"name":"NODE_0000074","node_attrs":{"div":531,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C184924T","-196616A","-196617A"],"OPG210":["S1190L"]},"labels":{"aa":"OPG210: S1190L"}},"children":[{"name":"OP936000","node_attrs":{"div":540,"accession":"OP936000","author":{"author":"Nguyen,D.T.,Le,H.M.,Huynh,H.T.T.,Tang,T.C.,Le,N.H.,Nguyen,H.H.,Nghiem,N.M.,Nguyen,H.T.T.,Vo,Q.T.,Vu,T.T.K.,Nguyen,T.T.,Phan,T.V.,Nguyen,T.L.N.,Le,T.M.,Vo,Q.M.,Dinh,M.N.H.,Nguyen,P.T.,Tran,P.T.L.,Tran,T.T.T.,Pham,T.T.N.,Nguyen,T.H.,Truong,L.T.T.,Nguyen,H.N.T.,Tran,T.T.,Le,K.T.T.,Lam,Y.M.,Thwaites,G.,Thwaites,L.,Nguyen,C.V.V.,Nguyen,A.T.,Le,T.V.","value":"Nguyen,D.T.,Le,H.M.,Huynh,H.T.T.,Tang,T.C.,Le,N.H.,Nguyen,H.H.,Nghiem,N.M.,Nguyen,H.T.T.,Vo,Q.T.,Vu,T.T.K.,Nguyen,T.T.,Phan,T.V.,Nguyen,T.L.N.,Le,T.M.,Vo,Q.M.,Dinh,M.N.H.,Nguyen,P.T.,Tran,P.T.L.,Tran,T.T.T.,Pham,T.T.N.,Nguyen,T.H.,Truong,L.T.T.,Nguyen,H.N.T.,Tran,T.T.,Le,K.T.T.,Lam,Y.M.,Thwaites,G.,Thwaites,L.,Nguyen,C.V.V.,Nguyen,A.T.,Le,T.V."},"country":{"value":"Vietnam"},"institution":{"value":"EI group, Oxford University Clinica Research Unit"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"strain":{"value":"Mpox-HCMC-M157"},"date":{"value":"2022-09-26"},"strain_display":{"value":"Vietnam/OP936000/2022-09-26"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["T647-","G648-","C32252T","G51559A","A86823T","G103706A","C152033T","T167015G","A167020T","A167021-","C167022-","G167029C","A187574C"]}}},{"name":"NODE_0000075","node_attrs":{"div":532,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G43103A","A136540-","T136541-","C136542-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"],"OPG063":["P196S"],"OPG153":["D381-"]},"labels":{"aa":"OPG063: P196S; OPG153: D381-"}},"children":[{"name":"OR455100","node_attrs":{"div":538,"accession":"OR455100","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"strain":{"value":"MpxV/human/USA/WA-UW-081251/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-08-XX"},"strain_display":{"value":"USA/OR455100/2023-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-609T","C29438T","G58696A","G120906A","G147352A","G178102A","C187942T","A192392-","A192393-","A192394-","T192395-","G192396-","A192397-","G192398-","T192399-","T192400-","A192401-","A192402-","T192403-","A192404-","G192405-"],"OPG046":["V98I"],"OPG078":["S39L"],"OPG138":["S76F"],"OPG171":["R122K"]},"labels":{"aa":"OPG046: V98I; OPG078: S39L; OPG138: S76F; OPG171: R122K"}}},{"name":"NODE_0000076","node_attrs":{"div":534,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G30868A","G102599A","-133098T","-133099T","-133100T","-169763A","-169764C","-169765A","-169766G","-169767A","-169768T","-169769A","-169770C","-169771A","-169772G","-169773A","-169774T"],"OPG122":["D58N"],"OPG197":["-32T","-33D","-34T","-35D"]},"labels":{"aa":"OPG122: D58N; OPG197: -32T, -33D, -34T, -35D"}},"children":[{"name":"OP331335","node_attrs":{"div":535,"accession":"OP331335","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"strain":{"value":"MPXV_UK_2022_9000155"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-03"},"strain_display":{"value":"United Kingdom/OP331335/2022-06-03"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T607-","T608-","-133101T","-133102T","-136540A","-136541T","-136542C","-136543A","-136544T","-136545C","-136546A","-136547T","-136548C","-136549A","-136550T","-136551C","-136552A","-136553T","-136554C","C164210T","-174531G","-174532A","-174533T","-174534G","-174535A","-174536A"],"OPG153":["-381D","-382D","-383D","-384D","-385D"],"OPG189":["S293L"]},"labels":{"aa":"OPG153: -381D, -382D, -383D, -384D, -385D; OPG189: S293L"}}},{"name":"OP605572","node_attrs":{"div":534,"accession":"OP605572","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.2.1"},"strain":{"value":"Slovenia-MPXV-30-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Slovenia/OP605572/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C165-","A196625-","T196626-","T196627-"]}}}]}]}]}]}]}]}]},{"name":"NODE_0000077","node_attrs":{"div":501,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A173314-","T173315-","A173316-","T173317-","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","C187428T"]}},"children":[{"name":"NODE_0000078","node_attrs":{"div":509,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G56968A","G61844A","C84008T","G96841A","C100971T","C134078T","C151050T","G188889-"],"OPG074":["S53L"],"OPG117":["D265N"],"OPG120":["E260K"]},"labels":{"aa":"OPG074: S53L; OPG117: D265N; OPG120: E260K","clade":"A.3"}},"children":[{"name":"MG693723","node_attrs":{"div":522,"accession":"MG693723","author":{"author":"Faye,O.,Pratt,C.B.,Faye,M.,Fall,G.,Chitty,J.A.,Diagne,M.M.,Wiley,M.R.,Yinka-Ogunleye,A.F.,Aruna,S.,Etebu,E.N.,Aworabhi,N.,Ogoina,D.,Numbere,W.,Mba,N.,Palacios,G.,Sall,A.A.,Ihekweazu,C.,Diagne,M.,Palacios,G.F.,Sall,A.","value":"Faye,O.,Pratt,C.B.,Faye,M.,Fall,G.,Chitty,J.A.,Diagne,M.M.,Wiley,M.R.,Yinka-Ogunleye,A.F.,Aruna,S.,Etebu,E.N.,Aworabhi,N.,Ogoina,D.,Numbere,W.,Mba,N.,Palacios,G.,Sall,A.A.,Ihekweazu,C.,Diagne,M.,Palacios,G.F.,Sall,A."},"country":{"value":"Nigeria"},"institution":{"value":"USAMRIID, Center for Genome Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"strain":{"value":"MPXV_Nig_2017_297957"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-XX-XX"},"strain_display":{"value":"Nigeria/MG693723/2017-XX-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A8143-","G8144-","C8145-","A8146-","T8147-","A8148-","T8149-","T8150-","A8151-","A8152-","A8153-","G8154-","T8155-","A8156-","A8157-","A8158-","A8159-","T8160-","C8161-","T8162-","A8163-","G8164-","T8165-","T8166-","A8167-","C8168-","C8169-","T8170-","T8171-","G8172-","A8173-","A8174-","A8175-","A8176-","T8177-","G8178-","A8179-","A8180-","T8181-","A8182-","C8183-","A8184-","G8185-","T8186-","G8187-","G8188-","G8189-","T8190-","G8191-","G8192-","T8193-","T8194-","C8195-","C8196-","G8197-","T8198-","A8199-","T8200-","C8201-","A8202-","C8203-","C8204-","A8205-","G8206-","T8207-","A8208-","A8209-","G8210-","A8211-","A8212-","C8213-","A8214-","T8215-","A8216-","A8217-","T8218-","A8219-","G8220-","T8221-","C8222-","G8223-","A8224-","A8225-","T8226-","A8227-","C8228-","A8229-","G8230-","T8231-","A8232-","T8233-","C8234-","C8235-","G8236-","A8237-","T8238-","T8239-","G8240-","A8241-","G8242-","A8243-","T8244-","T8245-","T8246-","T8247-","G8248-","C8249-","A8250-","T8251-","A8252-","C8253-","A8254-","A8255-","T8256-","A8257-","C8258-","T8259-","A8260-","G8261-","T8262-","C8263-","T8264-","A8265-","G8266-","A8267-","A8268-","A8269-","G8270-","A8271-","A8272-","A8273-","T8274-","T8275-","T8276-","G8277-","T8278-","A8279-","A8280-","T8281-","C8282-","A8283-","T8284-","C8285-","C8286-","T8287-","C8288-","T8289-","G8290-","T8291-","G8292-","A8293-","C8294-","A8295-","G8296-","G8297-","A8298-","G8299-","T8300-","C8301-","C8302-","A8303-","T8304-","A8305-","T8306-","A8307-","T8308-","C8309-","T8310-","G8311-","T8312-","A8313-","T8314-","C8315-","A8316-","T8317-","C8318-","G8319-","T8320-","C8321-","T8322-","A8323-","G8324-","T8325-","T8326-","T8327-","T8328-","T8329-","A8330-","T8331-","C8332-","A8333-","G8334-","T8335-","G8336-","T8337-","C8338-","C8339-","T8340-","A8341-","T8342-","G8343-","C8344-","T8345-","A8346-","T8347-","A8348-","T8349-","T8350-","C8351-","C8352-","T8353-","G8354-","T8355-","T8356-","A8357-","T8358-","C8359-","A8360-","T8361-","C8362-","A8363-","T8364-","T8365-","A8366-","G8367-","T8368-","T8369-","A8370-","A8371-","T8372-","G8373-","A8374-","A8375-","A8376-","A8377-","T8378-","A8379-","A8380-","C8381-","T8382-","C8383-","T8384-","C8385-","G8386-","T8387-","G8388-","C8389-","T8390-","T8391-","C8392-","A8393-","G8394-","A8395-","A8396-","A8397-","A8398-","G8399-","T8400-","C8401-","A8402-","A8403-","A8404-","T8405-","A8406-","T8407-","T8408-","G8409-","T8410-","A8411-","T8412-","C8413-","C8414-","A8415-","T8416-","A8417-","C8418-","A8419-","T8420-","A8421-","T8422-","A8423-","T8424-","C8425-","T8426-","C8427-","C8428-","A8429-","A8430-","A8431-","A8432-","C8433-","T8434-","A8435-","T8436-","C8437-","A8438-","C8439-","T8440-","T8441-","A8442-","T8443-","A8444-","C8445-","G8446-","T8447-","T8448-","T8449-","A8450-","T8451-","C8452-","T8453-","T8454-","T8455-","A8456-","A8457-","C8458-","G8459-","A8460-","A8461-","C8462-","A8463-","T8464-","A8465-","T8466-","A8467-","C8468-","C8469-","T8470-","A8471-","G8472-","A8473-","T8474-","G8475-","G8476-","T8477-","T8478-","A8479-","T8480-","T8481-","T8482-","A8483-","C8484-","T8485-","A8486-","A8487-","C8488-","A8489-","G8490-","A8491-","C8492-","A8493-","T8494-","T8495-","T8496-","T8497-","T8498-","T8499-","C8500-","A8501-","A8502-","G8503-","A8504-","T8505-","C8506-","T8507-","A8508-","T8509-","T8510-","G8511-","A8512-","C8513-","A8514-","A8515-","T8516-","A8517-","A8518-","C8519-","T8520-","C8521-","C8522-","T8523-","A8524-","T8525-","A8526-","G8527-","T8528-","T8529-","T8530-","C8531-","C8532-","A8533-","C8534-","A8535-","T8536-","C8537-","A8538-","A8539-","C8540-","C8541-","A8542-","A8543-","G8544-","T8545-","A8546-","A8547-","T8548-","G8549-","A8550-","T8551-","C8552-","A8553-","T8554-","C8555-","T8556-","A8557-","T8558-","T8559-","G8560-","T8561-","T8562-","A8563-","T8564-","A8565-","T8566-","A8567-","A8568-","C8569-","A8570-","A8571-","T8572-","A8573-","A8574-","C8575-","A8576-","T8577-","A8578-","A8579-","C8580-","T8581-","C8582-","T8583-","T8584-","T8585-","T8586-","C8587-","C8588-","A8589-","T8590-","T8591-","T8592-","T8593-","T8594-","A8595-","T8596-","C8597-","A8598-","G8599-","T8600-","A8601-","T8602-","C8603-","T8604-","A8605-","T8606-","A8607-","T8608-","C8609-","A8610-","A8611-","C8612-","G8613-","T8614-","C8615-","G8616-","T8617-","T8618-","G8619-","T8620-","A8621-","G8622-","T8623-","G8624-","A8625-","A8626-","T8627-","A8628-","G8629-","T8630-","A8631-","G8632-","T8633-","C8634-","A8635-","T8636-","T8637-","G8638-","A8639-","T8640-","C8641-","T8642-","A8643-","T8644-","T8645-","A8646-","T8647-","A8648-","T8649-","G8650-","A8651-","A8652-","A8653-","C8654-","G8655-","G8656-","A8657-","T8658-","A8659-","T8660-","G8661-","T8662-","C8663-","T8664-","A8665-","G8666-","T8667-","T8668-","A8669-","A8670-","T8671-","A8672-","T8673-","T8674-","T8675-","T8676-","C8677-","T8678-","T8679-","T8680-","G8681-","A8682-","T8683-","T8684-","T8685-","A8686-","A8687-","A8688-","G8689-","T8690-","C8691-","T8692-","A8693-","T8694-","A8695-","G8696-","T8697-","C8698-","T8699-","T8700-","T8701-","A8702-","C8703-","A8704-","A8705-","A8706-","C8707-","A8708-","T8709-","A8710-","A8711-","T8712-","A8713-","T8714-","C8715-","C8716-","T8717-","T8718-","A8719-","T8720-","C8721-","C8722-","G8723-","A8724-","C8725-","T8726-","T8727-","T8728-","A8729-","T8730-","A8731-","T8732-","T8733-","T8734-","C8735-","C8736-","T8737-","G8738-","T8739-","A8740-","G8741-","G8742-","G8743-","T8744-","G8745-","G8746-","C8747-","A8748-","T8749-","A8750-","A8751-","T8752-","T8753-","T8754-","T8755-","A8756-","T8757-","T8758-","C8759-","T8760-","G8761-","C8762-","C8763-","T8764-","C8765-","C8766-","A8767-","C8768-","A8769-","A8770-","T8771-","C8772-","A8773-","G8774-","T8775-","G8776-","T8777-","T8778-","T8779-","C8780-","C8781-","A8782-","A8783-","A8784-","T8785-","A8786-","T8787-","A8788-","T8789-","T8790-","A8791-","C8792-","T8793-","A8794-","G8795-","A8796-","C8797-","A8798-","A8799-","T8800-","A8801-","T8802-","T8803-","C8804-","C8805-","A8806-","T8807-","A8808-","T8809-","A8810-","G8811-","T8812-","T8813-","A8814-","T8815-","T8816-","A8817-","G8818-","T8819-","T8820-","A8821-","A8822-","G8823-","G8824-","G8825-","A8826-","C8827-","C8828-","C8829-","A8830-","A8831-","T8832-","T8833-","A8834-","G8835-","A8836-","A8837-","C8838-","A8839-","C8840-","G8841-","T8842-","A8843-","C8844-","G8845-","C8846-","G8847-","C8848-","T8849-","T8850-","A8851-","T8852-","T8853-","C8854-","A8855-","T8856-","C8857-","A8858-","T8859-","T8860-","T8861-","G8862-","G8863-","A8864-","T8865-","C8866-","G8867-","T8868-","A8869-","T8870-","T8871-","T8872-","C8873-","A8874-","T8875-","A8876-","A8877-","A8878-","A8879-","G8880-","T8881-","T8882-","A8883-","T8884-","T8885-","A8886-","T8887-","G8888-","T8889-","T8890-","A8891-","T8892-","A8893-","G8894-","A8895-","T8896-","G8897-","T8898-","C8899-","A8900-","A8901-","C8902-","A8903-","C8904-","A8905-","T8906-","T8907-","C8908-","T8909-","A8910-","C8911-","A8912-","T8913-","T8914-","T8915-","T8916-","T8917-","T8918-","T8919-","A8920-","A8921-","T8922-","T8923-","G8924-","T8925-","C8926-","T8927-","A8928-","T8929-","A8930-","T8931-","A8932-","G8933-","T8934-","A8935-","T8936-","T8937-","T8938-","T8939-","T8940-","C8941-","T8942-","G8943-","A8944-","T8945-","A8946-","T8947-","T8948-","T8949-","T8950-","C8951-","T8952-","A8953-","T8954-","A8955-","A8956-","T8957-","A8958-","T8959-","C8960-","A8961-","G8962-","A8963-","A8964-","T8965-","T8966-","G8967-","T8968-","C8969-","T8970-","T8971-","C8972-","C8973-","A8974-","T8975-","A8976-","G8977-","G8978-","A8979-","A8980-","G8981-","T8982-","T8983-","G8984-","T8985-","A8986-","T8987-","A8988-","C8989-","T8990-","A8991-","T8992-","T8993-","C8994-","G8995-","G8996-","A8997-","A8998-","T8999-","C9000-","A9001-","G9002-","T9003-","T9004-","A9005-","C9006-","A9007-","T9008-","G9009-","T9010-","T9011-","T9012-","A9013-","A9014-","A9015-","T9016-","A9017-","A9018-","T9019-","T9020-","C9021-","T9022-","C9023-","T9024-","G9025-","A9026-","T9027-","G9028-","T9029-","C9030-","A9031-","T9032-","T9033-","C9034-","C9035-","T9036-","T9037-","A9038-","T9039-","A9040-","C9041-","A9042-","A9043-","T9044-","C9045-","A9046-","A9047-","A9048-","T9049-","T9050-","C9051-","A9052-","T9053-","T9054-","A9055-","T9056-","T9057-","A9058-","A9059-","A9060-","C9061-","A9062-","G9063-","T9064-","T9065-","T9066-","A9067-","A9068-","T9069-","A9070-","G9071-","T9072-","C9073-","T9074-","G9075-","T9076-","A9077-","G9078-","A9079-","C9080-","C9081-","T9082-","T9083-","T9084-","A9085-","T9086-","C9087-","G9088-","T9089-","C9090-","G9091-","T9092-","A9093-","C9094-","A9095-","T9096-","A9097-","T9098-","C9099-","C9100-","A9101-","T9102-","T9103-","G9104-","T9105-","C9106-","T9107-","T9108-","A9109-","T9110-","T9111-","A9112-","G9113-","T9114-","T9115-","A9116-","C9117-","G9118-","C9119-","T9120-","T9121-","A9122-","T9123-","T9124-","T9125-","T9126-","T9127-","A9128-","T9129-","G9130-","G9131-","G9132-","T9133-","T9134-","T9135-","T9136-","A9137-","C9138-","G9139-","T9140-","T9141-","G9142-","C9143-","T9144-","T9145-","T9146-","A9147-","T9148-","T9149-","A9150-","T9151-","A9152-","T9153-","T9154-","T9155-","T9156-","A9157-","T9158-","A9159-","A9160-","T9161-","A9162-","A9163-","T9164-","G9165-","A9166-","T9167-","T9168-","G9169-","T9170-","T9171-","T9172-","G9173-","A9174-","C9175-","A9176-","A9177-","T9178-","G9179-","T9180-","C9181-","G9182-","T9183-","A9184-","G9185-","T9186-","A9187-","T9188-","A9189-","G9190-","A9191-","T9192-","A9193-","T9194-","A9195-","T9196-","T9197-","A9198-","T9199-","T9200-","A9201-","G9202-","A9203-","G9204-","G9205-","A9206-","G9207-","G9208-","T9209-","A9210-","T9211-","A9212-","A9213-","T9214-","T9215-","A9216-","T9217-","A9218-","A9219-","A9220-","A9221-","A9222-","G9223-","T9224-","T9225-","T9226-","C9227-","T9228-","G9229-","A9230-","G9231-","T9232-","A9233-","C9234-","G9235-","A9236-","T9237-","G9238-","T9239-","T9240-","A9241-","T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","C9257-","A9258-","T9259-","T9260-","A9261-","A9262-","C9263-","A9264-","T9265-","C53702T","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","A166866-","C166867-","T166868-","G166869-","A166870-","T166871-","G166872-","A166873-","T166874-","A166875-","A166876-","T166877-","A166878-","A166879-","T166880-","G166881-","A166882-","A166883-","T166884-","T166885-","G166886-","G166887-","T166888-","G166889-","T166890-","T166891-","A166892-","A166893-","A166894-","T166895-","T166896-","T166897-","T166898-","A166899-","A166900-","A166901-","G166902-","A166903-","G166904-","T166905-","A166906-","C166907-","A166908-","C166909-","A166910-","A166911-","T166912-","T166913-","T166914-","C166915-","T166916-","A166917-","T166918-","T166919-","A166920-","T166921-","T166922-","A166923-","C166924-","A166925-","G166926-","A166927-","G166928-","T166929-","C166930-","A166931-","T166932-","G166933-","T166934-","G166935-","A166936-","C166937-","G166938-","T166939-","C166940-","G166941-","G166942-","A166943-","T166944-","T166945-","T166946-","G166947-","A166948-","T166949-","T166950-","C166951-","C166952-","A166953-","T166954-","A166955-","G166956-","A166957-","T166958-","A166959-","T166960-","A166961-","G166962-","A166963-","T166964-","G166965-","T166966-","T166967-","A166968-","T166969-","A166970-","A166971-","A166972-","C166973-","G166974-","A166975-","C166976-","T166977-","A166978-","T166979-","A166980-","A166981-","A166982-","A166983-","T166984-","T166985-","A166986-","T166987-","T166988-","G166989-","A166990-","T166991-","A166992-","T166993-","G166994-","T166995-","A166996-","T166997-","A166998-","C166999-","C168582A","C168584-","T168585-","C168586-","T168587-","G168588-","T168589-","A168590-","T168591-","T168592-","T168593-","C168594-","T168595-","G168596-","T168597-","A168598-","T168599-","A168600-","T168601-","T168602-","G168603-","T168604-","G168605-","A168606-","T168607-","C168608-","A168609-","A168610-","G168611-","A168612-","G168613-","G168614-","C168615-","G168616-","G168617-","G168618-","A168619-","G168620-","T168624G","A168626-","A168627-","A168628-","T168629-","T168630-","T168631-","G168632-","A168633-","G168634-","G168635-","A168636-","G168637-","T168638-","A168639-","T168640-","A168641-","C168642-","T168643-","C168644-","A168645-","A168646-","G168647-","A168648-","A168649-","T168650-","C168651-","A168652-","A168653-","G168654-","T168655-","G168656-","A168657-","T168658-","A168659-","T168660-","C168661-","A168662-","G168663-","T168664-","A168665-","T168666-","T168667-","A168668-","A168674-","A168675-","G168676-","T168677-","A168678-","T168679-","G168680-","A168681-","T168682-","T168683-","C168684-","A168685-","T168686-","C168687-","A168688-","T168689-","G168690-","T168691-","A168692-","T168693-","T168694-","G168695-","A168696-","T168697-","T168698-","A168699-","T168700-","G168704-","G168705-","T168706-","A168707-","T168708-","T168709-","A168710-","A168711-","T168712-","C168713-","A168714-","A168715-","A168716-","G168717-","T168718-","T168719-","T168720-","C168721-","A168722-","T168723-","G168724-","A168725-","A168726-","T168727-","T168731C","G168732A","A168734T","C168737G","G168741-","A168742-","A168743-","T168744-","A168748T","C168750G","G168755-","A168756-","T168757-","A168758-","G168759-","A168760-","G168761-","A168762-","A168763-","T168764-","C168765-","A168766-","T168767-","G168768-","C168769-","G168770-","T168771-","C168772-","A168773-","G168774-","A168775-","T168777G","C169569-","A169570-","T169571-","T169572-","T169573-","A169574-","A169575-","T169576-","A169577-","A169578-","G169579-","G169580-","A169581-","C169582-","A169583-","T169584-","T169585-","G169586-","G169587-","A169588-","T169589-","A169590-","T169591-","G169592-","T169593-","G169594-","G169595-","A169596-","A169597-","A169598-","A169599-","G169600-","T169601-","G169602-","A169603-","T169604-","G169605-","T169606-","A169607-","T169608-","G169609-","G169610-","A169611-","A169612-","G169613-","T169614-","T169615-","A169616-","G169617-","T169618-","A169619-","C169620-","A169621-","T169622-","T169623-","A169624-","T169625-","C169626-","A169627-","A169628-","C169629-","T169630-","T169631-","C169632-","T169633-","C169634-","C169635-","T169636-","T169637-","A169638-","T169639-","T169640-","G169641-","A169642-","T169643-","T169644-","G169645-","A169646-","A169647-","A169648-","A169649-","T169650-","G169651-","A169652-","A169653-","A169654-","A169655-","T169656-","A169657-","T169658-","A169659-","A169660-","A169661-","T169662-","A169663-","G169664-","T169665-","T169666-","T169667-","T169668-","T169669-","A169670-","T169671-","G169672-","T169673-","A169674-","T169675-","A169676-","G169677-","C169678-","G169679-","G169680-","T169681-","A169682-","T169683-","C169684-","T169685-","A169686-","C169687-","C169688-","C169689-","T169690-","A169691-","T169692-","A169693-","G169694-","T169695-","T169696-","T169697-","T169698-","A169699-","T169700-","T169701-","G169702-","C169703-","T169704-","T169705-","A169706-","C169707-","T169708-","A169709-","C169710-","T169711-","A169712-","A169713-","C169714-","A169715-","T169716-","G169717-","G169718-","A169719-","T169720-","T169721-","C169722-","A169723-","G169724-","A169725-","T169726-","A169727-","C169728-","A169729-","G169730-","A169731-","T169732-","A169733-","C169734-","A169735-","G169736-","A169737-","T169738-","A169739-","C169740-","A169741-","G169742-","A169743-","T169744-","A169745-","C169746-","A169747-","G169748-","A169749-","T169750-","A169751-","C169752-","A169753-","G169754-","A169755-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","T187263G","A187265-","G187266-","A187267-","A187268-","T187269-","C187270-","A187271-","T187272-","T187273-","T187274-","A187275-","T187276-","C187277-","A187278-","T187279-","A187280-","A187281-","C187282-","T187283-","A187284-","T187285-","G187286-","T187287-","T187288-","T187289-","A187290-","A187291-","T187292-","A187293-","A187294-","A187295-","T187296-","T187297-","C187298-","A187299-","T187300-","C187301-","A187302-","A187303-","C187304-","G187305-","A187306-","A187307-","T187308-","A187309-","T187310-","C187311-","G187312-","A187313-","T187314-","A187315-","A187316-","A187317-","G187318-","A187319-","C187320-","C187321-","T187322-","C187323-","T187324-","T187325-","G187326-","T187327-","A187328-","A187329-","T187330-","T187331-","C187332-","G187333-","A187334-","G187335-","T187336-","A187337-","T187338-","A187339-","G187340-","G187341-","A187342-","A187343-","G187344-","T187345-","A187346-","G187347-","T187348-","A187349-","T187350-","T187351-","A187352-","C187353-","C187354-","A187355-","T187356-","A187357-","T187358-","C187359-","A187360-","A187361-","C187362-","C187366T","A187372-","A187373-","C187374-","A187375-","A187376-","T187377-","T187378-","A187379-","C187380-","T187381-","C187382-","T187383-","A187384-","A187385-","A187386-","A187387-","C187388-","A187389-","T187390-","G187391-","A187392-","G187393-","G187394-","A187395-","T187396-","T187397-","G187398-","T187399-","A187400-","C187401-","T187402-","C187403-","C187404-","T187405-","G187406-","T187407-","C187408-","T187409-","T187410-","G187415-","G187416-","A187417-","G187418-","A187419-","T187420-","C187421-","A187422-","C187423-","T187424-","A187425-","T187426-","T187427-","T187428-","A187429-","G187430-","T187431-","C187432-","G187433-","T187434-","T187435-","G187436-","A187437-","T187438-","A187439-","A187440-","A187441-","C187442-","T187443-","A187444-","G187445-","T187446-","A187447-","A187448-","C187449-","C187450-","T187451-","C187452-","A187453-","G187454-","G187455-","T187456-","T187457-","T187458-","C187459-","T187460-","T187461-","T187462-","A187463-","C187464-","A187465-","A187466-","A187467-","C187468-","G187469-","A187470-","T187471-","A187472-","A187473-","A187474-","G187475-","T187476-","A187477-","C187478-","A187479-","A187480-","C187481-","A187482-","T187483-","C187484-","A187485-","A187486-","G187487-","A187488-","C187489-","C187490-","T187491-","C187492-","A187493-","C187494-","A187495-","A187496-","C187497-","A187498-","C187499-","A187500-","G187501-","T187502-","G187503-","C187504-","A187505-","A187506-","G187507-","A187508-","T187509-","T187510-","A187511-","A187512-","T187513-","C187514-","T187515-","A187516-","G187517-","A187518-","A187519-","A187520-","T187521-","C187522-","A187523-","A187524-","A187525-","T187526-","G187527-","T187528-","A187529-","A187530-","T187531-","T187532-","C187533-","T187534-","G187535-","G187536-","A187537-","G187538-","G187539-","C187545-","T187546-","A187547-","G187548-","A187549-","C187550-","A187551-","A187552-","C187553-","T187554-","A187555-","A187556-","C187557-","A187558-","C187559-","C187560-","C187561-","A187562-","C187563-","G187564-","G187565-","C187566-","G187567-","A187568-","A187569-","G187570-","T187571-","A187572-","T187573-","A187574-","C187575-","T187576-","T187577-","T187578-","A187579-","T187580-","G187581-","C187582-","C187583-","T187584-","C187585-","A187586-","T187587-","T187588-","C187589-","A187590-","G187591-","A187592-","A187593-","A187594-","C187595-","G187596-","G187597-","T187598-","A187599-","A187600-","C187601-","T187602-","G187603-","T187604-","A187605-","G187606-","T187607-","A187608-","G187609-","G187610-","A187611-","G187612-","A187613-","C187614-","T187615-","G187616-","T187617-","C187618-","T187619-","C187620-","T187621-","C187622-","T187623-","A187624-","A187625-","T187626-","C187627-","T187628-","C187629-","G187630-","A187631-","T187632-","G187633-","T187634-","A187635-","T187636-","A187637-","T187638-","A187639-","T187640-","A187641-","A187642-","T187643-","A187644-","T187645-","A187646-","T187647-","A187648-","C187649-","C187650-","A187651-","A187652-","T187653-","A187654-","C187655-","G187656-","G187657-","A187658-","C187659-","G187660-","C187661-","G187662-","A187663-","T187664-","A187665-","T187666-","A187667-","T187668-","T187669-","C187670-","C187671-","G187672-","A187673-","C187674-","A187675-","T187676-","G187677-","A187678-","A187679-","T187680-","G187681-","G187682-","C187683-","G187684-","T187685-","C187686-","G187687-","C187688-","T187689-","T187690-","A187691-","T187692-","C187693-","A187694-","T187695-","A187696-","T187697-","G187698-","T187699-","T187700-","A187701-","T187702-","A187703-","T187704-","C187705-","C187706-","T187707-","A187708-","A187709-","A187710-","T187711-","G187712-","T187713-","T187714-","G187715-","A187716-","T187717-","C187718-","A187719-","T187720-","A187721-","T187722-","T187723-","C187724-","C187725-","A187726-","C187727-","A187728-","A187729-","A187730-","T187731-","G187732-","A187733-","T187734-","T187735-","G187736-","T187737-","G187738-","A187739-","A187740-","C187741-","G187742-","A187743-","G187744-","A187745-","T187746-","T187747-","A187748-","A187749-","A187750-","T187751-","C187752-","A187753-","T187754-","C187755-","T187756-","A187757-","A187758-","C187759-","A187760-","A187761-","A187762-","T187763-","A187764-","A187765-","T187766-","T187767-","A187768-","G187769-","T187770-","T187771-","T187772-","T187773-","T187774-","T187775-","A187776-","T187777-","G187778-","A187779-","C187780-","A187781-","T187782-","T187783-","A187784-","A187785-","C187786-","A187787-","T187788-","A187789-","T187790-","A187791-","A187792-","T187793-","A187794-","A187795-","A187796-","T187797-","A187798-","A187799-","A187800-","T187801-","T187802-","A187803-","A187804-","T187805-","C187806-","A187807-","T187808-","T187809-","A187810-","T187811-","T187812-","G187813-","A187814-","C187815-","T187816-","T187817-","A187818-","A187819-","C187820-","G187821-","A187822-","T187823-","G187824-","A187825-","C187826-","G187827-","A187828-","A187829-","A187830-","G187831-","T187832-","T187833-","A187834-","T187835-","C187836-","A187837-","T187838-","T187839-","A187840-","T187841-","C187842-","T187843-","T187844-","A187845-","G187846-","G187847-","A187848-","T187849-","T187850-","C187851-","T187852-","T187853-","G187854-","A187855-","T187856-","T187857-","A187858-","T187859-","T187860-","A187861-","A187862-","T187863-","A187864-","C187865-","A187866-","A187867-","A187868-","T187869-","T187870-","C187871-","G187872-","T187873-","T187874-","T188117-","T188118-","A188119-","T188120-","C188121-","G188122-","T188123-","C188124-","T188125-","C188126-","C188127-","T188128-","T188129-","A188130-","A188131-","A188132-","G188133-","C188134-","T188135-","T188136-","C188137-","T188138-","G188139-","A188140-","T188141-","G188142-","G188143-","T188144-","A188145-","A188146-","C188147-","T188148-","G188149-","T188150-","G188151-","T188152-","T188153-","A188154-","C188155-","A188156-","T188157-","G188158-","T188159-","G188160-","C188161-","T188162-","C188163-","C188164-","T188165-","A188166-","A188167-","A188168-","A188169-","C188170-","A188171-","A188172-","A188173-","A188174-","T188175-","A188176-","T188177-","G188178-","G188179-","T188180-","C188181-","G188182-","T188183-","G188184-","T188185-","G188186-","T188187-","A188188-","C188189-","G188190-","G188191-","A188192-","A188193-","A188194-","G188195-","A188196-","A188197-","A188198-","G188199-","G188200-","A188201-","G188202-","A188203-","A188204-","A188205-","A188206-","T188207-","G188208-","A188209-","T188210-","A188211-","T188212-","G188213-","G188214-","A188215-","A188216-","T188217-","A188218-","C188219-","C188220-","A188221-","T188222-","T188223-","T188224-","G188225-","T188226-","A188227-","A188228-","G188229-","A188230-","A188231-","A188232-","T188233-","G188234-","T188235-","C188236-","G188237-","G188238-","A188239-","A188240-","G188241-","G188242-","G188243-","T188244-","A188245-","C188246-","T188247-","T188248-","A188249-","T188250-","T188251-","C188252-","A188253-","G188254-","A188255-","T188256-","A188257-","T188258-","T188259-","G188260-","T188261-","A188262-","T188263-","C188264-","T188265-","G188266-","A188267-","C188268-","T188269-","C188270-","T188271-","G188272-","A188273-","T188274-","C188275-","A188276-","A188277-","T188278-","G188279-","T188280-","A188281-","A188282-","A188283-","C188284-","C188285-","T188286-","A188287-","T188288-","G188289-","A188290-","C188291-","A188292-","A188293-","G188294-","A188295-","T188296-","A188297-","A188298-","G188299-","A188300-","C188301-","T188302-","T188303-","A188304-","C188305-","T188306-","C188307-","G188308-","C188309-","A188310-","T188311-","C188312-","T188313-","A188314-","C188315-","T188316-","G188317-","G188318-","A188319-","T188320-","A188321-","G188322-","A188323-","C188324-","A188325-","T188326-","A188327-","A188328-","A188329-","T188330-","A188331-","T188332-","C188333-","C188334-","T188335-","C188336-","C188337-","T188338-","C188339-","G188340-","T188341-","A188342-","A188343-","T188344-","A188345-","A188346-","T188347-","G188348-","A188349-","A188350-","A188351-","T188352-","A188353-","T188354-","A188355-","A188356-","T188357-","A188358-","T188359-","A188360-","C188361-","A188362-","C188363-","T188364-","A188365-","A188366-","T188367-","T188368-","A188369-","T188370-","T188371-","A188372-","A188373-","T188374-","A188375-","T188376-","C188377-","A188378-","A188379-","T188380-","C188381-","G188382-","A188383-","G188384-","T188385-","A188386-","T188387-","T188388-","A188389-","A188390-","C188391-","A188392-","T188393-","A188394-","T188395-","A188396-","A188397-","G188398-","T188399-","T188400-","A188401-","T188402-","T188403-","T188404-","T188405-","T188406-","A188407-","A188408-","A188409-","C188410-","C188411-","C188412-","C188413-","T188414-","T188415-","T188416-","T188417-","G188418-","G188419-","G188420-","T188421-","T188422-","C188423-","C188424-","G188425-","T188426-","C188427-","C188428-","T188429-","A188430-","A188431-","A188432-","C188433-","G188434-","G188435-","C188436-","G188437-","T188438-","T188439-","T188440-","C188441-","G188442-","G188443-","T188444-","C188445-","T188446-","G188447-","T188448-","G188449-","T188450-","C188451-","G188452-","C188453-","C188454-","A188455-","C188456-","C188457-","A188458-","T188459-","G188460-","G188461-","T188462-","C188463-","A188464-","C188465-","A188466-","C188467-","C188468-","G188469-","A188470-","G188471-","C188472-","C188473-","T188474-","C188475-","T188476-","G188477-","C188478-","G188479-","T188480-","G188481-","C188482-","T188483-","C188484-","C188485-","T188486-","C188487-","C188488-","A188489-","T188490-","C188491-","G188492-","A188493-","G188494-","G188495-","A188496-","C188497-","G188498-","A188499-","C188500-","T188501-","T188502-","C188503-","A188504-","A188505-","C188506-","T188507-","A188508-","T188509-","G188510-","A188511-","C188512-","A188513-","G188514-","C188515-","T188516-","C188517-","G188518-","G188519-","T188520-","G188521-","G188522-","C188523-","G188524-","T188525-","C188526-","T188527-","G188528-","C188529-","C188530-","A188531-","G188532-","C188533-","G188534-","T188535-","G188536-","T188537-","A188538-","C188539-","A188540-","T188541-","A188542-","C188543-","G188544-","A188545-","A188546-","T188547-","G188548-","G188549-","C188550-","A188551-","T188552-","T188553-","T188554-","C188555-","T188556-","A188557-","A188558-","G188559-","A188560-","A188561-","A188562-","A188563-","G188564-","T188565-","C188566-","T188567-","A188568-","C188569-","G188570-","G188571-","T188572-","A188573-","T188574-","C188575-","C188576-","T188577-","T188578-","T188579-","C188580-","T188581-","A188582-","C188583-","A188584-","A188585-","T188586-","T188587-","T188588-","C188589-","C188590-","T188591-","T188592-","T188593-","A188594-","A188595-","C188596-","A188597-","A188598-","C188599-","G188600-","G188601-","C188602-","A188603-","A188604-","C188605-","A188606-","G188607-","C188608-","T188609-","G188610-","C188611-","A188612-","G188613-","T188614-","A188615-","T188616-","T188617-","T188618-","T188619-","T188620-","A188621-","T188622-","A188623-","C188624-","T188625-","T188626-","T188627-","G188628-","A188629-","A188630-","T188631-","G188632-","C188633-","A188634-","T188635-","C188636-","G188637-","G188638-","A188639-","C188640-","A188641-","T188642-","T188643-","T188644-","A188645-","T188646-","A188647-","C188648-","A188649-","A188650-","G188651-","G188652-","G188653-","A188654-","G188655-","T188656-","C188657-","C188658-","T188659-","G188660-","T188661-","T188662-","C188663-","T188664-","A188665-","A188666-","T188667-","A188668-","T188669-","T188670-","G188671-","G188672-","C188673-","A188674-","T188675-","C188676-","A188677-","A188678-","T188679-","G188680-","T188681-","T188682-","C188683-","G188684-","G188685-","A188686-","T188687-","C188688-","T188689-","A188690-","T188691-","A188692-","G188693-","G188694-","C188695-","T188696-","T188697-","G188698-","A188699-","T188700-","T188701-","T188702-","T188703-","C188704-","G188705-","C188706-","A188707-","T188708-","T188709-","G188710-","A188711-","C188712-","T188713-","T188714-","T188715-","A188716-","C188717-","A188718-","C188719-","A188720-","G188721-","A188722-","C188723-","A188724-","T188725-","G188726-","A188727-","A188728-","C188729-","A188730-","T188731-","C188732-","C188733-","C188734-","C188735-","T188736-","G188737-","A188738-","A188739-","T188740-","C188741-","T188742-","G188743-","T188744-","A188745-","C188746-","A188747-","T188748-","A188749-","C188750-","T188751-","T188752-","T188753-","G188754-","T188755-","G188756-","G188757-","A188758-","T188759-","T188760-","T188761-","A188762-","C188763-","A188764-","C188765-","T188766-","G188767-","T188768-","T188769-","A188770-","G188771-","A188772-","A188773-","T188774-","C188775-","T188776-","C188777-","T188778-","A188779-","A188780-","C188781-","G188782-","C188783-","T188784-","G188785-","G188786-","C188787-","C188788-","T188789-","C188790-","T188791-","G188792-","T188793-","T188794-","G188795-","T188796-","T188797-","A188798-","C188799-","T188800-","T188801-","T188802-","C188803-","T188804-","A188805-","T188806-","G188807-","A188808-","T188809-","G188810-","C188811-","A188812-","C188813-","G188814-","T188815-","A188816-","T188817-","C188818-","G188819-","T188820-","T188821-","A188822-","T188823-","G188824-","C188825-","A188826-","A188827-","G188828-","C188829-","T188830-","T188831-","T188832-","C188833-","A188834-","T188835-","G188836-","T188837-","T188838-","G188839-","A188840-","C188841-","T188842-","A188843-","C188844-","T188845-","G188846-","C188847-","A188848-","G188849-","T188850-","G188851-","T188852-","T188853-","T188854-","C188855-","T188856-","T188857-","G188858-","C188859-","T188860-","C188861-","T188862-","G188863-","A188864-","C188865-","T188866-","A188867-","C188868-","A188869-","T188870-","A188871-","T188872-","A188873-","C188874-","T188875-","C188876-","T188877-","A188878-","C188879-","A188880-","A188881-","T188882-","C188883-","A188884-","A188885-","A188886-","G188887-","A188888-","A188890-","G188891-","A188892-","T188893-","T188894-","T188895-","C188896-","A188897-","G188898-","T188899-","A188900-","A188901-","A188902-","C188903-","T188904-","T188905-","G188906-","T188907-","A188908-","A188909-","C188910-","A188911-","G188912-","G188913-","A188914-","T188915-","T188916-","G188917-","T188918-","T188919-","T188920-","G188921-","C188922-","T188923-","G188924-","C188925-","T188926-","T188927-","T188928-","C188929-","T188930-","G188931-","G188932-","A188933-","T188934-","T188935-","T188936-","T188937-","A188938-","A188939-","T188940-","T188941-","T188942-","T188943-","G188944-","T188945-","C188946-","A188947-","G188948-","G188949-","A188950-","G188951-","T188952-","C188953-","T188954-","T188955-","G188956-","A188957-","G188958-","G188959-","A188960-","T188961-","A188962-","A188963-","A188964-","G188965-","T188966-","T188967-","T188968-","A188969-","A188970-","A188971-","A188972-","T188973-","A188974-","G188975-","A188976-","A188977-","T188978-","T188979-","A188980-","A188981-","T188982-","A188983-","A188984-","A188985-","G188986-","A188987-","A188988-","C188989-","A188990-","T188991-","A188992-","T188993-","A188994-","G188995-","G188996-","T188997-","C188998-","A188999-","T189000-","T189001-","T189002-","T189003-","T189004-","T189005-","A189006-","A189007-","A189008-","C189009-","A189010-","T189011-","G189012-","G189013-","A189014-","T189015-","A189016-","G189017-","A189018-","A189019-","A189020-","C189021-","C189022-","A189023-","A189024-","G189025-","T190132-","A190133-","T190134-","T190135-","A190136-","A190137-","T190138-","G190139-","G190140-","A190141-","T190142-","A190143-","T190144-","A190145-","T190146-","A190147-","G190148-","A190149-","T190150-","A190151-","A190152-","C190153-","G190154-","C190155-","A190156-","A190157-","T190158-","A190159-","G190160-","G190161-","G190162-","A190163-","C190164-","T190165-","A190166-","A190167-","T190168-","A190169-","G190170-","T190171-","A190172-","T190173-","T190174-","G190175-","T190176-","A190177-","A190178-","A190179-","A190180-","G190181-","A190182-","T190183-","A190184-","T190185-","G190345A"],"OPG071":["R246Q"],"OPG192":["T46-","D47-","D48-","N49-","N50-","E51-","L52-","V53-","L54-","N55-","F56-","K57-","E58-","Y59-","T60-","I61-","S62-","I63-","I64-","T65-","E66-","S67-","C68-","D69-","V70-","G71-","F72-","D73-","S74-","I75-","D76-","I77-","D78-","V79-","I80-","N81-","D82-","Y83-","K84-","I85-","I86-","D87-","M88-","Y89-","T90-"],"OPG195":["T118N","L119-","C120-","I121-","S122-","V123-","Y124-","C125-","D126-","Q127-","E128-","A129-","G130-","D131-","I172-","L210-","K211-","S212-","K213-","A214-","L215-","H216-"]},"labels":{"aa":"OPG071: R246Q; OPG192: T46-, D47-, D48-, N49-, N50-, E51-, L52-, V53-, L54-, N55-, F56-, K57-, E58-, Y59-, T60-, I61-, S62-, I63-, I64-, T65-, E66-, S67-, C68-, D69-, V70-, G71-, F72-, D73-, S74-, I75-, D76-, I77-, D78-, V79-, I80-, N81-, D82-, Y83-, K84-, I85-, I86-, D87-, M88-, Y89-, T90-; OPG195: T118N, L119-, C120-, I121-, S122-, V123-, Y124-, C125-, D126-, Q127-, E128-, A129-, G130-, D131-, I172-, L210-, K211-, S212-, K213-, A214-, L215-, H216-"}}},{"name":"NODE_0000079","node_attrs":{"div":514,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C23353T","C51809T","G69678A","C125492T","C128174T","-188889A"],"OPG039":["D256N"],"OPG071":["R877Q"],"OPG146":["D50N"]},"labels":{"aa":"OPG039: D256N; OPG071: R877Q; OPG146: D50N"}},"children":[{"name":"NODE_0000080","node_attrs":{"div":515,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T27971C","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","-173314A","-173315T","-173316A","-173317T"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}},"children":[{"name":"MK783033","node_attrs":{"div":525,"accession":"MK783033","author":{"author":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J.","value":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J."},"country":{"value":"Nigeria"},"institution":{"value":"CDC, NCEZID/DHCPP/PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"strain":{"value":"MK783033"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-10-09"},"strain_display":{"value":"Nigeria/MK783033/2017-10-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-608T","C25731T","C25768T","C26020T","A56968G","G102267T","C117099T","G129583A","C155707T","G161701A","T187428C"],"OPG042":["D360N"],"OPG074":["L53S"],"OPG121":["G160C"],"OPG136":["R830Q"],"OPG188":["V36I"]},"labels":{"aa":"OPG042: D360N; OPG074: L53S; OPG121: G160C; OPG136: R830Q; OPG188: V36I"}}},{"name":"OP535335","node_attrs":{"div":515,"accession":"OP535335","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"strain":{"value":"MPXV_Nigeria_2017_2947"},"host":{"value":"Homo sapiens"},"date":{"value":"2017-10-XX"},"strain_display":{"value":"Nigeria/OP535335/2017-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000081","node_attrs":{"div":519,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T607-","C92053T","C123000T","C146052T","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","C150831T","C151305T"],"OPG113":["S108L"],"OPG143":["E106K"]},"labels":{"aa":"OPG113: S108L; OPG143: E106K"}},"children":[{"name":"OP612677","node_attrs":{"div":522,"accession":"OP612677","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"strain":{"value":"MPXV/015/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-03-12"},"strain_display":{"value":"Nigeria/OP612677/2019-03-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C56351T","G74032A","T76087-","A89106-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","G190782A"],"OPG016":["E125K"],"OPG074":["E259K"],"OPG094":["A85T"]},"labels":{"aa":"OPG016: E125K; OPG074: E259K; OPG094: A85T"}}},{"name":"NODE_0000082","node_attrs":{"div":548,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C2930T","C18493T","C18908T","G21898A","G23626A","C25254T","C29199T","G36901A","G44085A","G63034A","G75099A","G75144A","G76509A","C87659T","G115332A","C115572T","G122627A","C128771T","C140739T","A149394-","G151519T","G151875A","C160008T","C160312T","G165130A","G168862A","-173314A","-173315T","-173316A","-173317T","G174491A","G176289A","G176366A","C177703T","G194280A","A196614-","A196615-"],"OPG003":["E560K"],"OPG003_dup":["E560K"],"OPG037":["S179L"],"OPG039":["H165Y"],"OPG045":["E22K"],"OPG064":["S605L"],"OPG082":["S140L"],"OPG097":["H123Y"],"OPG109":["E597K"],"OPG133":["R42Q","S122F"],"OPG143":["T230M"],"OPG178":["G4V","D123N"],"OPG205":["A212T","M237I","S683L"]},"labels":{"aa":"OPG003: E560K; OPG003_dup: E560K; OPG037: S179L; OPG039: H165Y; OPG045: E22K; OPG064: S605L; OPG082: S140L; OPG097: H123Y; OPG109: E597K; OPG133: R42Q, S122F; OPG143: T230M; OPG178: G4V, D123N; OPG205: A212T, M237I, S683L"}},"children":[{"name":"OP413718","node_attrs":{"div":548,"accession":"OP413718","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"strain":{"value":"9000360"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP413718/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T133171-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"]}}},{"name":"OP536812","node_attrs":{"div":548,"accession":"OP536812","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.3"},"strain":{"value":"9000450"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536812/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000083","node_attrs":{"div":513,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C23564T","C72362T","C83326T","G87230A","G87297A","G91728A","C119296T","C121320T","G125249A","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","G148412A","C164832T","C168120T","T173297-","A173298-","T173299-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-"],"OPG092":["D196N"],"OPG105":["S734L"],"OPG109":["H740Y"],"OPG136":["D98N"],"OPG139":["A17T"],"OPG145":["E435K"],"OPG193":["L263F"]},"labels":{"aa":"OPG092: D196N; OPG105: S734L; OPG109: H740Y; OPG136: D98N; OPG139: A17T; OPG145: E435K; OPG193: L263F","clade":"A.1"}},"children":[{"name":"MT903343","node_attrs":{"div":516,"accession":"MT903343","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"United Kingdom"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-UK_P1"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-09-XX"},"strain_display":{"value":"United Kingdom/MT903343/2018-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-608T","G28838A","G92349A","-173297T","-173298A","-173299T","-173314A","-173315T","-173316A","-173317T","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G188494A","-196616A"],"OPG045":["A142V"],"OPG113":["E207K"]},"labels":{"aa":"OPG045: A142V; OPG113: E207K"}}},{"name":"MN648051","node_attrs":{"div":517,"accession":"MN648051","author":{"author":"Cohen Gihon,I.,Israeli,O.,Shifman,O.,Erez,N.,Melamed,S.,Paran,N.,Beth-Din,A.,Zvi,A.","value":"Cohen Gihon,I.,Israeli,O.,Shifman,O.,Erez,N.,Melamed,S.,Paran,N.,Beth-Din,A.,Zvi,A."},"country":{"value":"Israel"},"institution":{"value":"Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MN648051"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-10-04"},"strain_display":{"value":"Israel/MN648051/2018-10-04"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["T607-","C8772T","C91363T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A147593T","G150568A","-173297T","-173298A","-173299T","G177273A","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A196615-"],"OPG172":["E56V"],"OPG205":["D540N"]},"labels":{"aa":"OPG172: E56V; OPG205: D540N"}}},{"name":"MT903341","node_attrs":{"div":515,"accession":"MT903341","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"Nigeria"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-M5320_M15_Bayelsa"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-08-14"},"strain_display":{"value":"Nigeria/MT903341/2018-08-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-608T","G3153-","A3154-","T3155-","T3156-","C3157-","G3158-","A3159-","A3160-","T3161-","C3162-","T3163-","C3164-","T3165-","T3166-","T3167-","G3168-","A3169-","G3170-","G3171-","A3172-","G3173-","A3174-","C3175-","T3176-","T3177-","A3178-","T3179-","G3180-","T3181-","C3182-","A3183-","C3184-","G3185-","A3186-","C3187-","T3188-","A3189-","C3190-","A3191-","T3192-","T3193-","T3194-","T3195-","T3196-","C3197-","G3198-","A3199-","T3200-","G3201-","A3202-","T3203-","G3204-","G3205-","A3206-","A3207-","T3208-","C3209-","T3210-","A3211-","T3212-","C3213-","T3214-","T3215-","A3216-","T3217-","C3218-","G3219-","A3220-","A3221-","T3222-","G3223-","A3224-","T3225-","A3226-","T3227-","A3228-","T3229-","T3230-","T3231-","T3232-","T3233-","C3234-","A3235-","T3236-","A3237-","A3238-","A3239-","T3240-","A3241-","C3242-","A3243-","C3244-","T3245-","T3246-","T3247-","T3248-","A3249-","T3250-","A3251-","G3252-","T3253-","C3254-","C3255-","T3256-","C3257-","G3258-","T3259-","T3260-","T3261-","A3262-","A3263-","A3264-","C3265-","A3266-","G3267-","A3268-","A3269-","T3270-","T3271-","T3272-","A3273-","G3274-","T3275-","A3276-","T3277-","G3278-","T3279-","A3280-","G3281-","T3282-","T3283-","C3284-","C3285-","G3286-","C3287-","A3288-","A3289-","A3290-","T3291-","G3292-","A3293-","C3294-","T3295-","C3296-","G3297-","T3298-","C3299-","C3300-","C3301-","T3302-","T3303-","A3304-","A3305-","T3306-","A3307-","G3308-","G3309-","C3310-","A3311-","G3312-","T3313-","A3314-","G3315-","G3316-","C3317-","T3318-","A3319-","T3320-","T3321-","A3322-","T3323-","C3324-","T3325-","T3326-","C3327-","T3328-","T3329-","T3330-","A3331-","C3332-","G3333-","T3334-","A3335-","G3336-","T3337-","G3338-","A3339-","T3340-","C3341-","G3342-","T3343-","C3344-","G3345-","T3346-","A3347-","G3348-","G3349-","G3350-","A3351-","G3352-","A3353-","G3354-","A3355-","A3356-","C3357-","T3358-","C3359-","C3360-","G3361-","A3362-","C3363-","A3364-","T3365-","C3366-","T3367-","T3368-","G3369-","T3370-","A3371-","G3372-","A3373-","A3374-","C3375-","A3376-","A3377-","C3378-","G3379-","A3380-","T3381-","T3382-","T3383-","A3384-","A3385-","T3386-","C3387-","A3388-","T3389-","A3390-","G3391-","G3392-","T3393-","A3394-","G3395-","A3396-","G3397-","A3398-","T3399-","A3400-","C3401-","T3402-","T3403-","T3404-","C3405-","A3406-","G3407-","T3408-","C3409-","T3410-","G3411-","T3412-","G3413-","G3414-","T3415-","G3416-","G3417-","A3418-","T3419-","A3420-","A3421-","T3422-","G3423-","T3424-","C3425-","A3426-","T3427-","T3428-","A3429-","A3430-","C3431-","G3432-","A3433-","C3434-","A3435-","T3436-","C3437-","C3438-","G3439-","C3440-","C3441-","T3442-","T3443-","G3444-","T3445-","A3446-","T3447-","A3448-","T3449-","A3450-","A3451-","T3452-","G3453-","T3454-","T3455-","T3456-","C3457-","T3458-","G3459-","T3460-","T3461-","T3462-","T3463-","C3464-","A3465-","A3466-","A3467-","C3468-","A3469-","C3470-","C3471-","A3472-","A3473-","G3474-","T3475-","C3476-","G3477-","A3478-","A3479-","T3480-","A3481-","C3482-","T3483-","G3484-","T3485-","C3486-","T3487-","T3488-","A3489-","T3490-","C3491-","G3492-","T3493-","C3494-","T3495-","T3496-","T3497-","A3498-","G3499-","T3500-","C3501-","G3502-","G3503-","A3504-","A3505-","G3506-","G3507-","T3508-","T3509-","G3510-","A3511-","T3512-","G3513-","T3514-","C3515-","G3516-","T3517-","A3518-","T3519-","C3520-","C3521-","G3522-","A3523-","T3524-","G3525-","T3526-","A3527-","T3528-","A3529-","C3530-","G3531-","A3532-","G3533-","G3534-","T3535-","A3536-","T3537-","G3538-","A3539-","G3540-","G3541-","C3542-","A3543-","A3544-","C3545-","A3546-","T3547-","T3548-","G3549-","T3550-","T3551-","A3552-","T3553-","T3554-","G3555-","C3556-","A3557-","A3558-","T3559-","T3560-","C3561-","T3562-","G3563-","G3564-","A3565-","A3566-","G3567-","G3568-","C3569-","G3570-","G3571-","T3572-","A3573-","T3574-","G3575-","A3576-","A3577-","G3578-","A3579-","G3580-","G3581-","A3582-","G3583-","T3584-","C3585-","A3586-","T3587-","T3588-","G3589-","T3590-","A3591-","T3592-","T3593-","A3594-","T3595-","A3596-","G3597-","T3598-","A3599-","T3600-","T3601-","C3602-","G3603-","T3604-","C3605-","T3606-","T3607-","T3608-","C3609-","T3610-","G3611-","A3612-","A3613-","T3614-","G3615-","T3616-","C3617-","G3618-","A3619-","A3620-","T3621-","C3622-","T3623-","A3624-","T3625-","C3626-","T3627-","A3628-","G3629-","T3630-","A3631-","G3632-","A3633-","T3634-","A3635-","C3636-","C3637-","G3638-","T3639-","A3640-","G3641-","T3642-","A3643-","T3644-","A3645-","T3646-","T3647-","G3648-","A3649-","G3650-","A3651-","G3652-","A3653-","G3654-","C3655-","G3656-","A3657-","C3658-","T3659-","T3660-","C3661-","C3662-","A3663-","T3664-","A3665-","T3666-","C3667-","C3668-","T3669-","T3670-","G3671-","A3672-","T3673-","T3674-","A3675-","T3676-","G3677-","T3678-","T3679-","T3680-","T3681-","A3682-","T3683-","G3684-","A3685-","A3686-","T3687-","A3688-","G3689-","A3690-","T3691-","A3692-","A3693-","A3694-","G3695-","T3696-","A3697-","G3698-","A3699-","T3700-","G3701-","T3702-","T3703-","G3704-","T3705-","C3706-","C3707-","T3708-","T3709-","C3710-","T3711-","T3712-","C3713-","C3714-","T3715-","T3716-","T3717-","T3718-","G3719-","T3720-","A3721-","A3722-","T3723-","T3724-","T3725-","C3726-","C3727-","C3728-","G3729-","T3730-","A3731-","T3732-","T3733-","T3734-","T3735-","T3736-","G3737-","T3738-","T3739-","C3740-","G3741-","T3742-","G3743-","C3744-","C3745-","A3746-","A3747-","T3748-","T3749-","G3750-","A3751-","G3752-","T3753-","A3754-","A3755-","C3756-","A3757-","T3758-","T3759-","A3760-","T3761-","G3762-","A3763-","G3764-","A3765-","A3766-","T3767-","A3768-","T3769-","G3770-","A3771-","C3772-","C3773-","T3774-","G3775-","T3776-","T3777-","G3778-","C3779-","A3780-","C3781-","A3782-","A3783-","T3784-","C3785-","G3786-","T3787-","T3788-","C3789-","T3790-","T3791-","T3792-","A3793-","T3794-","G3795-","T3796-","A3797-","T3798-","T3799-","C3800-","C3801-","A3802-","T3803-","G3804-","A3805-","T3806-","G3807-","G3808-","G3809-","T3810-","G3811-","T3812-","A3813-","C3814-","A3815-","A3816-","T3817-","C3818-","A3819-","A3820-","G3821-","A3822-","T3823-","T3824-","A3825-","T3826-","T3827-","A3828-","C3829-","G3830-","T3831-","A3832-","T3833-","C3834-","C3835-","T3836-","C3837-","G3838-","T3839-","A3840-","T3841-","C3842-","G3843-","G3844-","C3845-","T3846-","C3847-","C3848-","T3849-","C3850-","G3851-","A3852-","G3853-","A3854-","T3855-","A3856-","A3857-","A3858-","A3859-","G3860-","A3861-","G3862-","C3863-","A3864-","T3865-","A3866-","C3867-","A3868-","C3869-","C3870-","A3871-","C3872-","A3873-","C3874-","G3875-","A3876-","G3877-","G3878-","A3879-","C3880-","T3881-","A3882-","T3883-","G3884-","T3885-","T3886-","T3887-","G3888-","G3889-","T3890-","A3891-","T3892-","A3893-","C3894-","T3895-","G3896-","T3897-","T3898-","G3899-","A3900-","A3901-","G3902-","G3903-","T3904-","A3905-","A3906-","G3907-","T3908-","G3909-","T3910-","G3911-","T3912-","A3913-","A3914-","C3915-","G3916-","G3917-","C3918-","G3919-","T3920-","A3921-","T3922-","T3923-","T3924-","C3925-","C3926-","G3927-","A3928-","T3929-","T3930-","T3931-","T3932-","C3933-","G3934-","T3935-","A3936-","A3937-","C3938-","C3939-","G3940-","C3941-","G3942-","T3943-","T3944-","A3945-","A3946-","T3947-","G3948-","T3949-","T3950-","T3951-","G3952-","C3953-","T3954-","C3955-","C3956-","A3957-","T3958-","G3959-","A3960-","T3961-","C3962-","T3963-","A3964-","T3965-","T3966-","A3967-","T3968-","C3969-","G3970-","C3971-","G3972-","T3973-","A3974-","G3975-","A3976-","T3977-","G3978-","A3979-","A3980-","T3981-","C3982-","G3983-","C3984-","T3985-","T3986-","C3987-","T3988-","C3989-","A3990-","G3991-","C3992-","T3993-","C3994-","G3995-","C3996-","A3997-","T3998-","C3999-","T4000-","T4001-","A4002-","G4003-","T4004-","G4005-","T4006-","G4007-","A4008-","C4009-","T4010-","C4011-","T4012-","T4013-","T4014-","G4015-","A4016-","C4017-","T4018-","T4019-","G4020-","T4021-","A4022-","A4023-","T4024-","A4025-","A4026-","T4027-","T4028-","G4029-","C4030-","T4031-","T4032-","T4033-","C4034-","G4035-","T4036-","G4037-","G4038-","A4039-","A4040-","C4041-","G4042-","C4043-","G4044-","G4045-","A4046-","T4047-","A4048-","T4049-","G4050-","T4051-","G4052-","T4053-","T4054-","T4055-","A4056-","C4057-","A4058-","G4059-","T4060-","A4061-","G4062-","T4063-","A4064-","A4065-","T4066-","G4067-","A4068-","A4069-","G4070-","A4071-","G4072-","A4073-","A4074-","G4075-","T4076-","G4077-","A4078-","G4079-","T4080-","C4081-","C4082-","A4083-","T4084-","C4085-","C4086-","T4087-","C4088-","A4089-","T4090-","C4091-","G4092-","A4093-","C4094-","G4095-","C4096-","A4097-","A4098-","T4099-","T4100-","A4101-","G4102-","G4103-","G4104-","T4105-","C4106-","A4107-","G4108-","A4109-","T4110-","C4111-","C4112-","T4113-","T4114-","T4115-","A4116-","G4117-","T4118-","C4119-","A4120-","A4121-","T4122-","A4123-","A4124-","T4125-","T4126-","T4127-","G4128-","T4129-","A4130-","C4131-","A4132-","G4133-","A4134-","A4135-","C4136-","G4137-","T4138-","A4139-","A4140-","T4141-","A4142-","G4143-","T4144-","T4145-","T4146-","A4147-","A4148-","G4149-","C4150-","T4151-","C4152-","C4153-","C4154-","A4155-","T4156-","T4157-","G4158-","A4159-","A4160-","T4161-","T4162-","T4163-","A4164-","T4165-","A4166-","T4167-","C4168-","T4169-","A4170-","A4171-","G4172-","A4173-","T4174-","A4175-","A4176-","C4177-","A4178-","C4179-","A4180-","G4181-","C4182-","A4183-","A4184-","T4185-","A4186-","G4187-","A4188-","T4189-","C4190-","G4191-","G4192-","A4193-","T4194-","G4195-","A4196-","T4197-","T4198-","T4199-","A4200-","C4201-","T4202-","A4203-","A4204-","A4205-","G4206-","T4207-","C4208-","A4209-","T4210-","C4211-","A4212-","A4213-","T4214-","G4215-","G4216-","G4217-","G4218-","T4219-","C4220-","C4221-","G4222-","T4223-","T4224-","A4225-","G4226-","T4227-","A4228-","T4229-","A4230-","T4231-","C4232-","A4233-","A4234-","A4235-","G4236-","A4237-","T4238-","C4239-","T4240-","T4241-","G4242-","T4243-","T4244-","A4245-","T4246-","C4247-","G4248-","A4249-","T4250-","T4251-","G4252-","A4253-","T4254-","A4255-","G4256-","T4257-","G4258-","A4259-","A4260-","T4261-","G4262-","A4263-","A4264-","T4265-","C4266-","A4267-","G4268-","A4269-","T4270-","A4271-","G4272-","T4273-","G4274-","G4275-","T4276-","G4277-","T4278-","A4279-","G4280-","A4281-","G4282-","G4283-","A4284-","A4285-","T4286-","A4287-","T4288-","G4289-","T4290-","C4291-","C4292-","T4293-","T4294-","T4295-","T4296-","T4297-","T4298-","A4299-","T4300-","C4301-","C4302-","T4303-","T4304-","G4305-","C4306-","T4307-","A4308-","T4309-","C4310-","A4311-","A4312-","A4313-","G4314-","T4315-","T4316-","A4317-","C4318-","G4319-","C4320-","A4321-","T4322-","G4323-","C4324-","C4325-","G4326-","T4327-","G4328-","G4329-","C4330-","G4331-","T4332-","A4333-","A4334-","C4335-","A4336-","A4337-","T4338-","A4339-","T4340-","C4341-","T4342-","T4343-","T4344-","A4345-","A4346-","T4347-","A4348-","C4349-","A4350-","G4351-","A4352-","T4353-","G4354-","G4355-","A4356-","T4357-","T4358-","A4359-","A4360-","A4361-","T4362-","C4363-","G4364-","T4365-","G4366-","T4367-","A4368-","T4369-","T4370-","C4371-","A4372-","T4373-","C4374-","G4375-","T4376-","A4377-","T4378-","A4379-","G4380-","C4381-","A4382-","A4383-","T4384-","G4385-","T4386-","A4387-","A4388-","T4389-","G4390-","G4391-","A4392-","G4393-","A4394-","G4395-","T4396-","T4397-","A4398-","C4399-","C4400-","A4401-","C4402-","A4403-","T4404-","T4405-","T4406-","T4407-","A4408-","G4409-","T4410-","C4411-","G4412-","T4413-","T4414-","T4415-","A4416-","T4417-","T4418-","C4419-","A4420-","G4421-","A4422-","T4423-","C4424-","G4425-","C4426-","A4427-","G4428-","T4429-","G4430-","T4431-","T4432-","T4433-","A4434-","A4435-","T4436-","A4437-","A4438-","C4439-","T4440-","A4441-","A4442-","T4443-","T4444-","T4445-","A4446-","A4447-","A4448-","C4449-","A4450-","G4451-","A4452-","T4453-","G4454-","A4455-","G4456-","A4457-","T4458-","G4459-","A4460-","T4461-","A4462-","T4463-","A4464-","T4465-","C4466-","C4467-","A4468-","C4469-","A4470-","T4471-","C4472-","A4473-","A4474-","A4475-","G4476-","A4477-","A4478-","T4479-","G4480-","C4481-","G4482-","A4483-","G4484-","A4485-","T4486-","A4487-","C4488-","A4489-","T4490-","A4491-","T4492-","G4493-","A4494-","C4495-","A4496-","G4497-","A4498-","C4499-","A4500-","T4501-","T4502-","A4503-","T4504-","T4505-","G4506-","A4507-","C4508-","A4509-","G4510-","A4511-","A4512-","A4513-","T4514-","G4515-","T4516-","G4517-","A4518-","C4519-","C4520-","T4521-","T4522-","C4523-","A4524-","T4525-","T4526-","A4527-","T4528-","C4529-","A4530-","C4531-","C4532-","G4533-","T4534-","C4535-","G4536-","T4537-","C4538-","C4539-","A4540-","T4541-","A4542-","A4543-","A4544-","T4545-","G4546-","C4547-","G4548-","T4549-","T4550-","A4551-","G4552-","G4553-","T4554-","A4555-","C4556-","G4557-","T4558-","A4559-","C4560-","C4561-","A4562-","C4563-","A4564-","T4565-","A4566-","C4567-","T4568-","A4569-","T4570-","C4571-","G4572-","T4573-","T4574-","A4575-","A4576-","C4577-","G4578-","A4579-","T4580-","G4581-","C4582-","G4583-","C4584-","A4585-","C4586-","A4587-","A4588-","T4589-","C4590-","T4591-","C4592-","G4593-","T4594-","C4595-","C4596-","A4597-","T4598-","T4599-","T4600-","C4601-","A4602-","T4603-","C4604-","C4605-","A4606-","T4607-","C4608-","T4609-","T4610-","C4611-","A4612-","T4613-","A4614-","A4615-","T4616-","G4617-","A4618-","T4619-","T4620-","T4621-","A4622-","C4623-","T4624-","T4625-","T4626-","T4627-","T4628-","C4629-","A4630-","T4631-","A4632-","A4633-","T4634-","T4635-","A4636-","G4637-","A4638-","G4639-","A4640-","A4641-","A4642-","A4643-","A4644-","G4645-","A4646-","T4647-","C4648-","A4649-","A4650-","G4651-","G4652-","T4653-","A4654-","T4655-","A4656-","A4657-","A4658-","A4659-","A4660-","T4661-","T4662-","A4663-","G4664-","A4665-","A4666-","G4667-","T4668-","G4669-","T4670-","T4671-","A4672-","G4673-","A4674-","C4675-","T4676-","A4677-","T4678-","A4679-","A4680-","A4681-","C4682-","T4683-","A4684-","A4685-","C4686-","T4687-","T4688-","A4689-","T4690-","G4691-","A4692-","C4693-","T4694-","T4695-","A4696-","A4697-","C4698-","T4699-","A4700-","A4701-","C4702-","T4703-","T4704-","A4705-","T4706-","G4707-","A4708-","C4709-","T4710-","T4711-","A4712-","A4713-","C4714-","T4715-","A4716-","A4717-","C4718-","T4719-","T4720-","A4721-","T4722-","G4723-","A4724-","C4725-","T4726-","T4727-","A4728-","A4729-","C4730-","T4731-","A4732-","A4733-","C4734-","T4735-","T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","A4748-","A4749-","C4750-","T4751-","T4752-","A4753-","T4754-","G4755-","A4756-","C4757-","T4758-","T4759-","A4760-","A4761-","C4762-","T4763-","A4764-","A4765-","C4766-","T4767-","T4768-","A4769-","T4770-","G4771-","A4772-","C4773-","T4774-","T4775-","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","A4807-","T4808-","T4809-","A4810-","A4811-","C4812-","T4813-","C4814-","A4815-","T4816-","T4817-","T4818-","C4819-","A4820-","A4821-","G4822-","A4823-","A4824-","A4825-","G4826-","G4827-","T4828-","G4829-","G4830-","G4831-","T4832-","G4833-","G4834-","A4835-","T4836-","A4837-","G4838-","A4839-","A4840-","C4841-","T4842-","C4843-","T4844-","A4845-","T4846-","A4847-","T4848-","G4849-","A4850-","C4851-","A4852-","G4853-","C4854-","T4855-","T4856-","G4857-","T4858-","G4859-","A4860-","A4861-","A4862-","C4863-","A4864-","A4865-","T4866-","T4867-","A4868-","G4869-","A4870-","T4871-","C4872-","C4873-","C4874-","T4875-","A4876-","A4877-","T4878-","T4879-","T4880-","C4881-","T4882-","A4883-","A4884-","T4885-","G4886-","G4887-","A4888-","A4889-","G4890-","T4891-","T4892-","T4893-","T4894-","G4895-","A4896-","T4897-","A4898-","G4899-","G4900-","A4901-","G4902-","A4903-","T4904-","T4905-","G4906-","T4907-","C4908-","A4909-","T4910-","C4911-","A4912-","G4913-","T4914-","T4915-","G4916-","A4917-","T4918-","A4919-","C4920-","A4921-","T4922-","T4923-","G4924-","T4925-","T4926-","T4927-","A4928-","T4929-","T4930-","A4931-","T4932-","C4933-","T4934-","C4935-","A4936-","T4937-","C4938-","T4939-","A4940-","T4941-","T4942-","A4943-","G4944-","A4945-","G4946-","C4947-","A4948-","C4949-","G4950-","T4951-","C4952-","T4953-","G4954-","T4955-","T4956-","T4957-","A4958-","G4959-","A4960-","G4961-","C4962-","T4963-","T4964-","T4965-","A4966-","G4967-","T4968-","G4969-","A4970-","C4971-","C4972-","T4973-","G4974-","C4975-","T4976-","C4977-","G4978-","G4979-","T4980-","T4981-","A4982-","C4983-","T4984-","T4985-","C4986-","T4987-","G4988-","T4989-","G4990-","T4991-","A4992-","A4993-","A4994-","T4995-","C4996-","T4997-","T4998-","G4999-","A5000-","A5001-","T5002-","C5003-","C5004-","T5005-","T5006-","T5007-","A5008-","G5009-","T5010-","G5011-","A5012-","T5013-","A5014-","C5015-","A5016-","C5017-","T5018-","G5019-","T5020-","G5021-","T5022-","C5023-","A5024-","A5025-","A5026-","A5027-","C5028-","T5029-","G5030-","G5031-","A5032-","T5033-","G5034-","T5035-","T5036-","T5037-","A5038-","G5039-","A5040-","A5041-","T5042-","A5043-","C5044-","C5045-","T5046-","A5047-","T5048-","G5049-","T5050-","A5051-","G5052-","A5053-","A5054-","T5055-","A5056-","T5057-","G5058-","G5059-","G5060-","A5061-","A5062-","G5063-","C5064-","A5065-","T5066-","G5067-","C5068-","T5069-","T5070-","G5071-","T5072-","T5073-","T5074-","T5075-","T5076-","G5077-","T5078-","C5079-","T5080-","C5081-","T5082-","A5083-","T5084-","T5085-","A5086-","T5087-","A5088-","G5089-","A5090-","T5091-","T5092-","A5093-","A5094-","C5095-","T5096-","C5097-","A5098-","T5099-","A5100-","C5101-","A5102-","T5103-","G5104-","G5105-","T5106-","T5107-","G5108-","T5109-","A5110-","T5111-","T5112-","A5113-","T5114-","G5115-","A5116-","A5117-","T5118-","T5119-","T5120-","T5121-","C5122-","A5123-","T5124-","C5125-","T5126-","G5127-","C5128-","C5129-","T5130-","A5131-","A5132-","T5133-","G5134-","T5135-","A5136-","C5137-","T5138-","C5139-","C5140-","A5141-","A5142-","T5143-","T5144-","C5145-","T5146-","T5147-","G5148-","T5149-","T5150-","T5151-","A5152-","C5153-","A5154-","A5155-","T5156-","C5157-","A5158-","A5159-","T5160-","T5161-","A5162-","T5163-","A5164-","T5165-","A5166-","A5167-","T5168-","C5169-","A5170-","A5171-","A5172-","G5173-","A5174-","G5175-","T5176-","G5177-","A5178-","T5179-","G5180-","A5181-","T5182-","G5183-","C5184-","A5185-","T5186-","A5187-","C5188-","A5189-","C5190-","A5191-","T5192-","T5193-","A5194-","C5195-","A5196-","A5197-","A5198-","G5199-","T5200-","G5201-","A5202-","A5203-","T5204-","A5205-","A5206-","T5207-","C5208-","T5209-","A5210-","C5211-","C5212-","A5213-","T5214-","C5215-","A5216-","T5217-","A5218-","A5219-","A5220-","A5221-","T5222-","A5223-","C5224-","T5225-","T5226-","G5227-","A5228-","T5229-","A5230-","C5231-","A5232-","G5233-","A5234-","G5235-","C5236-","T5237-","T5238-","T5239-","A5240-","T5241-","C5242-","A5243-","C5244-","A5245-","T5246-","C5247-","A5248-","T5249-","G5250-","G5251-","T5252-","T5253-","T5254-","T5255-","C5256-","A5257-","A5258-","T5259-","T5260-","G5261-","T5262-","A5263-","T5264-","T5265-","A5266-","T5267-","T5268-","A5269-","A5270-","G5271-","T5272-","A5273-","T5274-","A5275-","G5276-","C5277-","T5278-","A5279-","A5280-","T5281-","T5282-","T5283-","T5284-","A5285-","T5286-","A5287-","C5288-","A5289-","G5290-","T5291-","C5292-","A5293-","A5294-","T5295-","A5296-","G5297-","A5298-","C5299-","A5300-","A5301-","T5302-","G5303-","G5304-","T5305-","T5306-","C5307-","T5308-","C5309-","T5310-","A5311-","A5312-","G5313-","C5314-","A5315-","A5316-","T5317-","A5318-","T5319-","T5320-","T5321-","C5322-","T5323-","A5324-","A5325-","T5326-","A5327-","T5328-","T5329-","T5330-","T5331-","A5332-","A5333-","G5334-","A5335-","T5336-","G5337-","T5338-","G5339-","C5340-","T5341-","T5342-","C5343-","C5344-","C5345-","T5346-","A5347-","C5348-","G5349-","G5350-","G5351-","C5352-","G5353-","A5354-","T5355-","G5356-","A5357-","C5358-","A5359-","G5360-","A5361-","T5362-","C5363-","C5364-","C5365-","C5366-","T5367-","A5368-","T5369-","C5370-","C5371-","A5372-","C5373-","G5374-","G5375-","C5376-","C5377-","A5378-","C5379-","G5380-","T5381-","C5382-","A5383-","A5384-","G5385-","A5386-","C5387-","A5388-","T5389-","G5390-","T5391-","A5392-","T5393-","A5394-","T5395-","C5396-","C5397-","A5398-","T5399-","T5400-","A5401-","C5402-","T5403-","C5404-","A5405-","T5406-","T5407-","A5408-","C5409-","T5410-","G5411-","C5412-","G5413-","T5414-","T5415-","G5416-","A5417-","C5418-","A5419-","T5420-","T5421-","T5422-","G5423-","C5424-","T5425-","C5426-","C5427-","A5428-","T5429-","T5430-","T5431-","T5432-","C5433-","T5434-","A5435-","A5436-","T5437-","A5438-","G5439-","C5440-","C5441-","A5442-","T5443-","G5444-","A5445-","T5446-","A5447-","C5448-","T5449-","A5450-","A5451-","A5452-","T5453-","C5454-","T5455-","A5456-","T5457-","A5458-","T5459-","A5460-","A5461-","C5462-","C5463-","T5464-","G5465-","C5466-","A5467-","T5468-","A5469-","G5470-","A5471-","T5472-","A5473-","G5474-","C5475-","G5476-","C5477-","G5478-","A5479-","T5480-","A5481-","A5482-","A5483-","G5484-","C5485-","A5486-","A5487-","G5488-","G5489-","T5490-","C5491-","C5492-","T5493-","T5494-","C5495-","C5496-","A5497-","C5498-","C5499-","A5500-","G5501-","C5502-","A5503-","T5504-","C5505-","T5506-","A5507-","G5508-","T5509-","T5510-","G5511-","A5512-","T5513-","T5514-","G5515-","A5516-","T5517-","A5518-","T5519-","C5520-","T5521-","T5522-","C5523-","A5524-","A5525-","T5526-","A5527-","T5528-","A5529-","T5530-","G5531-","G5532-","G5533-","A5534-","T5535-","A5536-","C5537-","A5538-","A5539-","A5540-","G5541-","C5542-","T5543-","T5544-","A5545-","T5546-","A5547-","A5548-","A5549-","T5550-","T5551-","T5552-","C5553-","T5554-","A5555-","A5556-","T5557-","A5558-","C5559-","T5560-","G5561-","T5562-","G5563-","G5564-","G5565-","T5566-","T5567-","C5568-","A5569-","T5570-","C5571-","T5572-","A5573-","C5574-","A5575-","A5576-","G5577-","G5578-","A5579-","A5580-","T5581-","C5582-","C5583-","C5584-","C5585-","T5586-","A5587-","G5588-","T5589-","A5590-","T5591-","A5592-","C5593-","T5594-","G5595-","A5596-","A5597-","T5598-","T5599-","A5600-","T5601-","T5602-","T5603-","T5604-","A5605-","T5606-","A5607-","T5608-","A5609-","G5610-","A5611-","T5612-","C5613-","T5614-","A5615-","A5616-","T5617-","T5618-","T5619-","A5620-","A5621-","C5622-","A5623-","T5624-","C5625-","A5626-","T5627-","T5628-","T5629-","T5630-","C5631-","A5632-","T5633-","C5634-","T5635-","G5636-","G5637-","G5638-","A5639-","T5640-","A5641-","C5642-","C5643-","A5644-","C5645-","A5646-","A5647-","T5648-","T5649-","C5650-","A5651-","A5652-","A5653-","A5654-","T5655-","A5656-","A5657-","A5658-","C5659-","T5660-","C5661-","A5662-","A5663-","C5664-","A5665-","A5666-","C5667-","A5668-","C5669-","T5670-","A5671-","C5672-","T5673-","T5674-","T5675-","C5676-","C5677-","T5678-","T5679-","T5680-","T5681-","T5682-","A5683-","C5684-","A5685-","T5686-","A5687-","T5688-","T5689-","C5690-","C5691-","C5692-","C5693-","T5694-","A5695-","A5696-","A5697-","A5698-","T5699-","A5700-","G5701-","G5702-","C5703-","A5704-","T5705-","T5706-","C5707-","A5708-","A5709-","G5710-","C5711-","A5712-","T5713-","T5714-","C5715-","T5716-","A5717-","T5718-","T5719-","T5720-","T5721-","A5722-","T5723-","A5724-","T5725-","A5726-","T5727-","T5728-","A5729-","C5730-","A5731-","G5732-","C5733-","C5734-","C5735-","C5736-","A5737-","T5738-","G5739-","A5740-","T5741-","C5742-","T5743-","A5744-","C5745-","C5746-","A5747-","T5748-","A5749-","A5750-","G5751-","A5752-","T5753-","C5754-","A5755-","A5756-","C5757-","A5758-","A5759-","T5760-","G5761-","T5762-","C5763-","T5764-","A5765-","T5766-","T5767-","T5768-","C5769-","T5770-","A5771-","C5772-","A5773-","T5774-","A5775-","T5776-","G5777-","C5778-","A5779-","T5780-","T5781-","A5782-","G5783-","A5784-","T5785-","A5786-","G5787-","A5788-","T5789-","A5790-","G5791-","T5792-","A5793-","A5794-","A5795-","G5796-","T5797-","A5798-","A5799-","G5800-","A5801-","G5802-","A5803-","T5804-","C5805-","T5806-","T5807-","G5808-","C5809-","A5810-","C5811-","A5812-","G5813-","A5814-","A5815-","T5816-","T5817-","A5818-","C5819-","A5820-","A5821-","T5822-","T5823-","C5824-","T5825-","T5826-","A5827-","A5828-","T5829-","A5830-","A5831-","T5832-","T5833-","A5834-","T5835-","A5836-","G5837-","A5838-","G5839-","A5840-","A5841-","A5842-","A5843-","T5844-","A5845-","T5846-","C5847-","T5848-","T5849-","C5850-","C5851-","A5852-","T5853-","A5854-","T5855-","A5856-","A5857-","T5858-","T5859-","C5860-","T5861-","T5862-","T5863-","G5864-","A5865-","C5866-","A5867-","C5868-","T5869-","A5870-","A5871-","T5872-","G5873-","C5874-","A5875-","G5876-","A5877-","T5878-","A5879-","T5880-","A5881-","A5882-","T5883-","A5884-","T5885-","C5886-","T5887-","T5888-","T5889-","A5890-","T5891-","A5892-","T5893-","G5894-","T5895-","A5896-","A5897-","T5898-","A5899-","T5900-","A5901-","T5902-","G5903-","C5904-","A5905-","A5906-","A5907-","C5908-","A5909-","G5910-","T5911-","C5912-","T5913-","A5914-","T5915-","C5916-","T5917-","A5918-","C5919-","T5920-","A5921-","T5922-","A5923-","T5924-","A5925-","C5926-","T5927-","G5928-","A5929-","T5930-","C5931-","A5932-","A5933-","T5934-","A5935-","T5936-","T5937-","A5938-","T5939-","C5940-","T5941-","C5942-","T5943-","A5944-","T5945-","G5946-","A5947-","A5948-","T5949-","C5950-","C5951-","T5952-","A5953-","A5954-","A5955-","A5956-","T5957-","A5958-","A5959-","T5960-","C5961-","A5962-","T5963-","A5964-","C5965-","A5966-","G5967-","A5968-","A5969-","C5970-","A5971-","T5972-","C5973-","T5974-","A5975-","C5976-","A5977-","G5978-","G5979-","A5980-","T5981-","C5982-","A5983-","C5984-","A5985-","A5986-","A5987-","T5988-","T5989-","G5990-","G5991-","T5992-","T5993-","C5994-","A5995-","A5996-","G5997-","G5998-","A5999-","G6000-","A6001-","A6002-","A6003-","T6004-","C6005-","T6006-","A6007-","T6008-","C6009-","A6010-","A6011-","A6012-","T6013-","A6014-","T6015-","T6016-","T6017-","T6018-","C6019-","C6020-","T6021-","G6022-","T6023-","C6024-","A6025-","A6026-","C6027-","A6028-","A6029-","C6030-","T6031-","G6032-","G6033-","T6034-","T6035-","C6036-","T6037-","A6038-","G6039-","A6040-","A6041-","C6042-","A6043-","T6044-","A6045-","A6046-","C6047-","A6048-","G6049-","T6050-","C6051-","A6052-","A6053-","C6054-","A6055-","C6056-","C6057-","T6058-","A6059-","A6060-","T6061-","C6062-","C6063-","A6064-","T6065-","G6066-","T6067-","T6068-","T6069-","T6070-","T6071-","T6072-","A6073-","T6074-","A6075-","A6076-","T6077-","C6078-","A6079-","T6080-","C6081-","T6082-","A6083-","C6084-","C6085-","A6086-","A6087-","A6088-","G6089-","A6090-","T6091-","A6092-","A6093-","T6094-","G6095-","A6096-","C6097-","C6098-","A6099-","A6100-","A6101-","G6102-","A6103-","T6104-","C6105-","G6106-","A6107-","G6108-","G6109-","T6110-","C6111-","G6112-","T6113-","C6114-","G6115-","T6116-","G6117-","A6118-","A6119-","A6120-","C6121-","T6122-","G6123-","C6124-","T6125-","C6126-","A6127-","T6128-","C6129-","G6130-","A6131-","C6132-","A6133-","G6134-","C6135-","C6136-","A6137-","T6138-","G6139-","A6140-","A6141-","A6142-","T6143-","C6144-","T6145-","A6146-","C6147-","C6148-","G6149-","A6150-","C6151-","T6152-","C6153-","C6154-","A6155-","T6156-","G6157-","G6158-","T6159-","G6160-","C6161-","G6162-","A6163-","A6164-","T6165-","C6166-","G6167-","C6168-","A6169-","C6170-","T6171-","G6172-","T6173-","C6174-","T6175-","T6176-","A6177-","T6178-","T6179-","C6180-","G6181-","C6182-","C6183-","A6184-","T6185-","T6186-","G6187-","A6188-","T6189-","T6190-","T6191-","T6192-","C6193-","A6194-","T6195-","T6196-","T6197-","T6198-","T6199-","T6200-","A6201-","T6202-","A6203-","A6204-","T6205-","T6206-","A6207-","T6208-","G6209-","T6210-","A6211-","C6212-","A6213-","T6214-","G6215-","T6216-","T6217-","T6218-","T6219-","C6220-","C6221-","T6222-","T6223-","C6224-","T6225-","A6226-","T6227-","T6228-","C6229-","T6230-","C6231-","A6232-","A6233-","G6234-","A6235-","G6236-","T6237-","C6238-","T6239-","A6240-","C6241-","A6242-","A6243-","A6244-","A6245-","A6246-","T6247-","A6248-","T6249-","A6250-","T6251-","T6252-","T6253-","T6254-","T6255-","T6256-","C6257-","G6258-","A6259-","T6260-","A6261-","T6262-","C6263-","T6264-","A6265-","A6266-","G6267-","T6268-","A6269-","C6270-","T6271-","A6272-","A6273-","G6274-","T6275-","T6276-","T6277-","T6278-","T6279-","T6280-","T6281-","A6282-","C6283-","T6284-","G6285-","T6286-","T6287-","T6288-","T6289-","T6290-","G6291-","T6292-","T6293-","A6294-","C6295-","T6296-","G6297-","T6298-","C6299-","T6300-","T6301-","C6302-","C6303-","A6304-","T6305-","T6306-","C6307-","T6308-","T6309-","C6310-","T6311-","A6312-","A6313-","C6314-","T6315-","A6316-","A6317-","A6318-","G6319-","A6320-","T6321-","C6322-","T6323-","G6324-","A6325-","G6326-","A6327-","T6328-","A6329-","A6330-","A6331-","T6332-","T6333-","A6334-","T6335-","A6336-","C6337-","A6338-","A6339-","T6340-","C6341-","T6342-","T6343-","C6344-","G6345-","C6346-","T6347-","A6348-","T6349-","C6350-","G6351-","A6352-","A6353-","C6354-","C6355-","A6356-","T6357-","T6358-","T6359-","T6360-","T6361-","G6362-","T6363-","A6364-","G6365-","T6366-","C6367-","T6368-","A6369-","A6370-","A6371-","G6372-","C6373-","C6374-","T6375-","G6376-","A6377-","A6378-","G6379-","T6380-","A6381-","A6382-","T6383-","T6384-","A6385-","A6386-","C6387-","C6388-","A6389-","A6390-","C6391-","T6392-","G6393-","T6394-","T6395-","T6396-","T6397-","T6398-","A6399-","T6400-","T6401-","A6402-","G6403-","T6404-","G6405-","G6406-","C6407-","T6408-","T6409-","T6410-","T6411-","T6412-","T6413-","C6414-","G6415-","A6416-","T6417-","C6418-","T6419-","A6420-","T6421-","C6422-","C6423-","T6424-","C6425-","G6426-","T6427-","C6428-","C6429-","T6430-","C6431-","T6432-","C6433-","A6434-","T6435-","C6436-","A6437-","T6438-","C6439-","C6440-","T6441-","T6442-","A6443-","T6444-","A6445-","T6446-","T6447-","A6448-","T6449-","T6450-","A6451-","T6452-","C6453-","A6454-","T6455-","T6456-","A6457-","T6458-","T6459-","A6460-","T6461-","C6462-","A6463-","T6464-","A6465-","G6466-","T6467-","C6468-","T6469-","A6470-","T6471-","T6472-","A6473-","A6474-","A6475-","C6476-","A6477-","C6478-","A6479-","A6480-","A6481-","T6482-","C6483-","A6484-","T6485-","C6486-","T6487-","A6488-","C6489-","G6490-","T6491-","T6492-","T6493-","A6494-","T6495-","A6496-","A6497-","C6498-","A6499-","A6500-","C6501-","A6502-","T6503-","T6504-","C6505-","T6506-","C6507-","A6508-","T6509-","T6510-","A6511-","T6512-","T6513-","A6514-","A6515-","T6516-","T6517-","A6518-","G6519-","T6520-","T6521-","C6522-","T6523-","G6524-","T6525-","A6526-","G6527-","A6528-","A6529-","T6530-","A6531-","T6532-","C6533-","T6534-","T6535-","T6536-","A6537-","A6538-","T6539-","A6540-","A6541-","T6542-","T6543-","T6544-","G6545-","G6546-","C6547-","T6548-","A6549-","T6550-","A6551-","C6552-","A6553-","T6554-","C6555-","T6556-","G6557-","T6558-","T6559-","C6560-","A6561-","A6562-","T6563-","A6564-","C6565-","T6566-","A6567-","T6568-","C6569-","T6570-","A6571-","T6572-","T6573-","G6574-","A6575-","T6576-","G6577-","A6578-","T6579-","T6580-","T6581-","C6582-","T6583-","T6584-","T6585-","T6586-","T6587-","T6588-","A6589-","A6590-","G6591-","A6592-","C6593-","T6594-","T6595-","A6596-","A6597-","A6598-","C6599-","T6600-","A6601-","G6602-","T6603-","T6604-","A6605-","T6606-","G6607-","G6608-","T6609-","A6610-","A6611-","T6612-","G6613-","A6614-","C6615-","G6616-","A6617-","T6618-","G6619-","A6620-","A6621-","A6622-","T6623-","C6624-","G6625-","A6626-","G6627-","T6628-","A6629-","G6630-","T6631-","A6632-","A6633-","C6634-","T6635-","T6636-","C6637-","T6638-","A6639-","A6640-","T6641-","A6642-","A6643-","A6644-","G6645-","A6646-","C6647-","T6648-","T6649-","G6650-","A6651-","T6652-","A6653-","T6654-","C6655-","A6656-","T6657-","T6658-","A6659-","T6660-","C6661-","A6662-","T6663-","A6664-","T6665-","G6666-","T6667-","T6668-","T6669-","G6670-","A6671-","T6672-","C6673-","G6674-","T6675-","C6676-","A6677-","T6678-","A6679-","G6680-","T6681-","T6682-","A6683-","A6684-","T6685-","A6686-","G6687-","T6688-","G6689-","T6690-","G6691-","G6692-","C6693-","T6694-","A6695-","A6696-","A6697-","T6698-","G6699-","G6700-","T6701-","A6702-","C6703-","T6704-","G6705-","T6706-","T6707-","A6708-","A6709-","T6710-","A6711-","A6712-","G6713-","T6714-","T6715-","T6716-","A6717-","T6718-","A6719-","G6720-","A6721-","C6722-","A6723-","A6724-","T6725-","A6726-","T6727-","C6728-","A6729-","T6730-","A6731-","G6732-","T6733-","A6734-","T6735-","T6736-","T6737-","T6738-","C6739-","T6740-","T6741-","T6742-","C6743-","C6744-","A6745-","G6746-","A6747-","A6748-","T6749-","T6750-","A6751-","G6752-","A6753-","T6754-","T6755-","A6756-","T6757-","T6758-","T6759-","T6760-","T6761-","T6762-","T6763-","A6764-","A6765-","A6766-","T6767-","A6768-","C6769-","T6770-","G6771-","A6772-","T6773-","C6774-","C6775-","T6776-","C6777-","A6778-","C6779-","A6780-","A6781-","T6782-","T6783-","C6784-","C6785-","G6786-","T6787-","G6788-","A6789-","T6790-","G6791-","T6792-","A6793-","G6794-","C6795-","A6796-","G6797-","T6798-","A6799-","G6800-","T6801-","T6802-","G6803-","G6804-","T6805-","G6806-","C6807-","A6808-","T6809-","G6810-","G6811-","T6812-","C6813-","T6814-","A6815-","T6816-","A6817-","T6818-","C6819-","G6820-","T6821-","T6822-","A6823-","A6824-","A6825-","A6826-","T6827-","G6828-","T6829-","A6830-","T6831-","C6832-","A6833-","T6834-","A6835-","T6836-","A6837-","T6838-","A6839-","A6840-","T6841-","A6842-","G6843-","T6844-","T6845-","T6846-","T6847-","C6848-","T6849-","G6850-","A6851-","C6852-","G6853-","T6854-","G6855-","G6856-","A6857-","G6858-","T6859-","A6860-","C6861-","A6862-","G6863-","A6864-","A6865-","T6866-","T6867-","T6868-","T6869-","C6870-","G6871-","A6872-","T6873-","T6874-","A6875-","A6876-","T6877-","G6878-","A6879-","G6880-","T6881-","T6882-","C6883-","A6884-","T6885-","G6886-","G6887-","T6888-","A6889-","A6890-","G6891-","G6892-","A6893-","A6894-","G6895-","G6896-","G6897-","C6898-","A6899-","A6900-","A6901-","T6902-","G6903-","C6904-","C6905-","T6906-","G6907-","T6908-","A6909-","T6910-","A6911-","T6912-","A6913-","A6914-","T6915-","A6916-","T6917-","A6918-","C6919-","A6920-","T6921-","A6922-","A6923-","G6924-","T6925-","T6926-","A6927-","A6928-","T6929-","A6930-","G6931-","T6932-","T6933-","T6934-","T6935-","T6936-","T6937-","A6938-","T6939-","C6940-","A6941-","T6942-","A6943-","T6944-","T6945-","T6946-","T6947-","C6948-","T6949-","A6950-","A6951-","T6952-","A6953-","C6954-","C6955-","A6956-","T6957-","A6958-","A6959-","T6960-","A6961-","A6962-","A6963-","A6964-","A6965-","T6966-","T6967-","A6968-","T6969-","C6970-","A6971-","T6972-","T6973-","A6974-","T6975-","T6976-","G6977-","C6978-","G6979-","T6980-","T6981-","T6982-","G6983-","G6984-","T6985-","A6986-","G6987-","T6988-","T6989-","C6990-","T6991-","G6992-","C6993-","C6994-","C6995-","T6996-","A6997-","T6998-","C6999-","A7000-","T7001-","C7002-","T7003-","A7004-","T7005-","A7006-","T7007-","C7008-","A7009-","C7010-","T7011-","G7012-","T7013-","C7014-","A7015-","C7016-","T7017-","C7018-","T7019-","C7020-","G7021-","C7022-","T7023-","C7024-","T7025-","C7026-","A7027-","C7028-","T7029-","A7030-","T7031-","A7032-","T7033-","C7034-","T7035-","T7036-","C7037-","T7038-","A7039-","A7040-","A7041-","A7042-","T7043-","T7044-","A7045-","C7046-","A7047-","A7048-","A7049-","C7050-","A7051-","A7052-","C7053-","T7054-","G7055-","G7056-","A7057-","T7058-","A7059-","T7060-","T7061-","C7062-","G7063-","A7064-","T7065-","A7066-","A7067-","C7068-","A7069-","G7070-","C7071-","A7072-","T7073-","T7074-","T7075-","G7076-","T7077-","G7078-","T7079-","A7080-","G7081-","T7082-","T7083-","T7084-","T7085-","T7086-","G7087-","T7088-","C7089-","T7090-","T7091-","T7092-","T7093-","A7094-","C7095-","A7096-","G7097-","T7098-","A7099-","T7100-","A7101-","T7102-","A7103-","C7104-","G7105-","T7106-","T7107-","A7108-","T7109-","T7110-","G7111-","T7112-","C7113-","A7114-","A7115-","A7116-","A7117-","T7118-","C7119-","T7120-","A7121-","A7122-","A7123-","C7124-","A7125-","A7126-","A7127-","T7128-","A7129-","T7130-","T7131-","A7132-","G7133-","C7134-","A7135-","T7136-","A7137-","A7138-","T7139-","A7140-","C7141-","A7142-","T7143-","C7144-","T7145-","A7146-","T7147-","C7148-","T7149-","A7150-","T7151-","A7152-","A7153-","G7154-","A7155-","T7156-","C7157-","A7158-","G7159-","G7160-","A7161-","T7162-","C7163-","C7164-","A7165-","T7166-","G7167-","T7168-","T7169-","C7170-","G7171-","A7172-","G7173-","C7174-","A7175-","T7176-","A7177-","C7178-","T7179-","A7180-","G7181-","C7182-","C7183-","A7184-","T7185-","G7186-","T7187-","A7188-","T7189-","A7190-","T7191-","T7192-","T7193-","G7194-","T7195-","A7196-","A7197-","C7198-","T7199-","T7200-","C7201-","G7202-","T7203-","C7204-","G7205-","T7206-","A7207-","C7208-","A7209-","G7210-","C7211-","G7212-","T7213-","T7214-","A7215-","G7216-","A7217-","T7218-","C7219-","A7220-","A7221-","T7222-","A7223-","G7224-","A7225-","A7226-","T7227-","A7228-","A7229-","A7230-","C7231-","A7232-","A7233-","T7234-","C7235-","G7236-","T7237-","G7238-","T7239-","G7240-","A7241-","C7242-","G7243-","C7244-","A7245-","A7246-","C7247-","T7248-","T7249-","T7250-","T7251-","T7252-","T7253-","A7254-","C7255-","G7256-","A7257-","T7258-","C7259-","T7260-","A7261-","G7262-","T7263-","T7264-","G7265-","T7266-","A7267-","T7268-","G7269-","A7270-","G7271-","T7272-","T7273-","T7274-","A7275-","T7276-","C7277-","G7278-","T7279-","T7280-","T7281-","A7282-","C7283-","A7284-","T7285-","A7286-","A7287-","G7288-","C7289-","A7290-","A7291-","T7292-","T7293-","A7294-","A7295-","C7296-","G7297-","G7298-","C7299-","T7300-","T7301-","T7302-","A7303-","A7304-","C7305-","A7306-","G7307-","A7308-","T7309-","G7310-","A7311-","T7312-","C7313-","T7314-","G7315-","A7316-","G7317-","T7318-","A7319-","A7320-","T7321-","A7322-","A7323-","T7324-","A7325-","T7326-","A7327-","C7328-","C7329-","T7330-","C7331-","T7332-","G7333-","T7334-","T7335-","A7336-","T7337-","A7338-","C7339-","G7340-","T7341-","T7342-","T7343-","A7344-","A7345-","T7346-","G7347-","T7348-","T7349-","C7350-","A7351-","C7352-","G7353-","G7354-","T7355-","C7356-","T7357-","T7358-","A7359-","G7360-","T7361-","A7362-","T7363-","T7364-","T7365-","T7366-","T7367-","A7368-","G7369-","A7370-","T7371-","A7372-","T7373-","C7374-","A7375-","A7376-","T7377-","T7378-","G7379-","T7380-","G7381-","A7382-","T7383-","T7384-","T7385-","A7386-","C7387-","A7388-","C7389-","C7390-","A7391-","T7392-","A7393-","T7394-","T7395-","C7396-","G7397-","A7398-","C7399-","T7400-","C7401-","C7402-","C7403-","T7404-","T7405-","G7406-","T7407-","G7408-","T7409-","G7410-","T7411-","A7412-","A7413-","C7414-","G7415-","T7416-","T7417-","A7418-","G7419-","A7420-","A7421-","A7422-","T7423-","T7424-","C7425-","T7426-","A7427-","A7428-","A7429-","T7430-","C7431-","T7432-","A7433-","T7434-","A7435-","T7436-","T7437-","A7438-","T7439-","C7440-","T7441-","A7442-","T7443-","T7444-","A7445-","C7446-","A7447-","G7448-","C7449-","G7450-","T7451-","A7452-","A7453-","A7454-","A7455-","C7456-","A7457-","C7458-","A7459-","T7460-","T7461-","C7462-","A7463-","A7464-","T7465-","A7466-","T7467-","T7468-","G7469-","T7470-","A7471-","T7472-","T7473-","G7474-","T7475-","T7476-","A7477-","T7478-","T7479-","T7480-","T7481-","T7482-","A7483-","T7484-","A7485-","T7486-","T7487-","A7488-","T7489-","T7490-","T7491-","A7492-","C7493-","A7494-","C7495-","A7496-","A7497-","T7498-","T7499-","A7500-","A7501-","C7502-","A7503-","A7504-","T7505-","G7506-","T7507-","A7508-","T7509-","T7510-","A7511-","T7512-","T7513-","A7514-","G7515-","T7516-","T7517-","T7518-","A7519-","T7520-","A7521-","T7522-","T7523-","A7524-","C7525-","T7526-","G7527-","A7528-","A7529-","T7530-","T7531-","A7532-","A7533-","T7534-","A7535-","A7536-","T7537-","A7538-","T7539-","A7540-","A7541-","A7542-","A7543-","T7544-","T7545-","C7546-","C7547-","C7548-","A7549-","A7550-","T7551-","C7552-","T7553-","T7554-","G7555-","T7556-","C7557-","A7558-","T7559-","A7560-","A7561-","A7562-","C7563-","A7564-","C7565-","A7566-","A7567-","A7568-","A7569-","T7570-","C7571-","C7572-","A7573-","T7574-","T7575-","A7576-","A7577-","A7578-","A7579-","A7580-","T7581-","G7582-","T7583-","C7584-","G7585-","A7586-","T7587-","A7588-","A7589-","A7590-","A7591-","T7592-","A7593-","T7594-","C7595-","T7596-","G7597-","A7598-","T7599-","G7600-","T7601-","T7602-","G7603-","T7604-","T7605-","G7606-","T7607-","T7608-","C7609-","G7610-","C7611-","T7612-","G7613-","C7614-","T7615-","A7616-","T7617-","G7618-","A7619-","T7620-","A7621-","A7622-","T7623-","C7624-","A7625-","G7626-","A7627-","T7628-","C7629-","A7630-","T7631-","T7632-","A7633-","G7634-","C7635-","C7636-","G7637-","A7638-","T7639-","A7640-","G7641-","T7642-","G7643-","G7644-","T7645-","A7646-","A7647-","T7648-","G7649-","C7650-","T7651-","A7652-","T7653-","C7654-","G7655-","A7656-","A7657-","A7658-","C7659-","A7660-","A7661-","C7662-","A7663-","T7664-","C7665-","G7666-","C7667-","C7668-","A7669-","G7670-","A7671-","A7672-","A7673-","T7674-","T7675-","A7676-","C7677-","A7678-","A7679-","A7680-","C7681-","G7682-","C7683-","T7684-","A7685-","C7686-","A7687-","A7688-","C7689-","A7690-","G7691-","A7692-","T7693-","A7694-","T7695-","T7696-","C7697-","C7698-","A7699-","G7700-","C7701-","T7702-","A7703-","T7704-","C7705-","A7706-","G7707-","A7708-","T7709-","T7710-","A7711-","T7712-","G7713-","T7714-","G7715-","G7716-","T7717-","C7718-","C7719-","A7720-","G7721-","A7722-","G7723-","G7724-","G7725-","A7726-","G7727-","A7728-","T7729-","G7730-","G7731-","A7732-","T7733-","A7734-","T7735-","T7736-","G7737-","T7738-","T7739-","T7740-","A7741-","C7742-","A7743-","C7744-","G7745-","G7746-","T7747-","G7748-","A7749-","C7750-","T7751-","G7752-","T7753-","A7754-","T7755-","C7756-","C7757-","A7758-","C7759-","G7760-","C7761-","T7762-","A7763-","G7764-","A7765-","G7766-","A7767-","T7768-","A7769-","T7770-","C7771-","G7772-","A7773-","C7774-","G7775-","G7776-","T7777-","A7778-","T7779-","G7780-","T7781-","A7782-","T7783-","T7784-","G7785-","T7786-","A7787-","G7788-","A7789-","T7790-","G7791-","C7792-","T7793-","C7794-","T7795-","C7796-","A7797-","T7798-","G7799-","G7800-","T7801-","T7802-","A7803-","T7804-","A7805-","C7806-","A7807-","G7808-","G7809-","T7810-","A7811-","T7812-","T7813-","A7814-","G7815-","A7816-","T7817-","G7818-","T7819-","C7820-","A7821-","G7822-","C7823-","A7824-","T7825-","G7826-","T7827-","A7828-","G7829-","T7830-","A7831-","T7832-","T7833-","A7834-","G7835-","T7836-","A7837-","G7838-","A7839-","C7840-","T7841-","A7842-","T7843-","C7844-","A7845-","A7846-","C7847-","G7848-","T7849-","T7850-","C7851-","A7852-","G7853-","G7854-","A7855-","A7856-","A7857-","A7858-","C7859-","C7860-","A7861-","G7862-","A7863-","C7864-","A7865-","C7866-","T7867-","A7868-","C7869-","A7870-","A7871-","C7872-","A7873-","T7874-","C7875-","A7876-","T7877-","A7878-","T7879-","A7880-","T7881-","C7882-","C7883-","C7884-","A7885-","T7886-","C7887-","T7888-","C7889-","T7890-","A7891-","G7892-","G7893-","T7894-","A7895-","T7896-","T7897-","G7898-","T7899-","G7900-","C7901-","T7902-","T7903-","G7904-","T7905-","A7906-","T7907-","T7908-","A7909-","G7910-","T7911-","A7912-","G7913-","G7914-","C7915-","A7916-","T7917-","T7918-","A7919-","T7920-","T7921-","A7922-","T7923-","T7924-","A7925-","C7926-","G7927-","T7928-","G7929-","T7930-","T7931-","G7932-","T7933-","C7934-","T7935-","A7936-","T7937-","T7938-","A7939-","T7940-","C7941-","T7942-","G7943-","T7944-","T7945-","T7946-","A7947-","T7948-","A7949-","T7950-","G7951-","T7952-","T7953-","C7954-","A7955-","C7956-","T7957-","C7958-","G7959-","A7960-","A7961-","G7962-","A7963-","A7964-","C7965-","T7966-","A7967-","A7968-","A7969-","C7970-","T7971-","A7972-","C7973-","C7974-","T7975-","A7976-","T7977-","A7978-","C7979-","A7980-","A7981-","G7982-","A7983-","T7984-","A7985-","T7986-","G7987-","G7988-","T7989-","T7990-","G7991-","T7992-","G7993-","T7994-","T7995-","A7996-","T7997-","A7998-","T7999-","T8000-","T8001-","T8002-","T8003-","T8004-","A8005-","T8006-","A8007-","A8008-","A8009-","A8010-","T8011-","T8012-","T8013-","T8014-","T8015-","T8016-","T8017-","A8018-","T8019-","G8020-","A8021-","G8022-","T8023-","A8024-","T8025-","T8026-","T8027-","T8028-","T8029-","A8030-","C8031-","A8032-","A8033-","A8034-","A8035-","A8036-","T8037-","G8038-","T8039-","A8040-","T8041-","A8042-","T8043-","G8044-","T8045-","A8046-","T8047-","A8048-","A8049-","A8050-","A8051-","A8052-","A8053-","A8054-","A8055-","T8056-","A8057-","C8058-","T8059-","A8060-","A8061-","G8062-","T8063-","A8064-","T8065-","A8066-","C8067-","G8068-","A8069-","T8070-","G8071-","T8072-","A8073-","T8074-","C8075-","C8076-","T8077-","G8078-","T8079-","A8080-","T8081-","T8082-","A8083-","T8084-","T8085-","T8086-","G8087-","T8088-","A8089-","T8090-","T8091-","T8092-","A8093-","T8094-","C8095-","T8096-","A8097-","A8098-","A8099-","C8100-","A8101-","A8102-","T8103-","A8104-","C8105-","T8106-","T8107-","C8108-","T8109-","G8110-","C8111-","C8112-","T8113-","C8114-","T8115-","A8116-","G8117-","A8118-","T8119-","G8120-","G8121-","G8122-","A8123-","T8124-","A8125-","C8126-","A8127-","A8128-","A8129-","A8130-","A8131-","T8132-","T8133-","T8134-","T8135-","T8136-","T8137-","A8138-","T8139-","T8140-","T8141-","C8142-","A8143-","G8144-","C8145-","A8146-","T8147-","A8148-","T8149-","T8150-","A8151-","A8152-","A8153-","G8154-","T8155-","A8156-","A8157-","A8158-","A8159-","T8160-","C8161-","T8162-","A8163-","G8164-","T8165-","T8166-","A8167-","C8168-","C8169-","T8170-","T8171-","G8172-","A8173-","A8174-","A8175-","A8176-","T8177-","G8178-","A8179-","A8180-","T8181-","A8182-","C8183-","A8184-","G8185-","T8186-","G8187-","G8188-","G8189-","T8190-","G8191-","G8192-","T8193-","T8194-","C8195-","C8196-","G8197-","T8198-","A8199-","T8200-","C8201-","A8202-","C8203-","C8204-","A8205-","G8206-","T8207-","A8208-","A8209-","G8210-","A8211-","A8212-","C8213-","A8214-","T8215-","A8216-","A8217-","T8218-","A8219-","G8220-","T8221-","C8222-","G8223-","A8224-","A8225-","T8226-","A8227-","C8228-","A8229-","G8230-","T8231-","A8232-","T8233-","C8234-","C8235-","G8236-","A8237-","T8238-","T8239-","G8240-","A8241-","G8242-","A8243-","T8244-","T8245-","T8246-","T8247-","G8248-","C8249-","A8250-","T8251-","A8252-","C8253-","A8254-","A8255-","T8256-","A8257-","C8258-","T8259-","A8260-","G8261-","T8262-","C8263-","T8264-","A8265-","G8266-","A8267-","A8268-","A8269-","G8270-","A8271-","A8272-","A8273-","T8274-","T8275-","T8276-","G8277-","T8278-","A8279-","A8280-","T8281-","C8282-","A8283-","T8284-","C8285-","C8286-","T8287-","C8288-","T8289-","G8290-","T8291-","G8292-","A8293-","C8294-","A8295-","G8296-","G8297-","A8298-","G8299-","T8300-","C8301-","C8302-","A8303-","T8304-","A8305-","T8306-","A8307-","T8308-","C8309-","T8310-","G8311-","T8312-","A8313-","T8314-","C8315-","A8316-","T8317-","C8318-","G8319-","T8320-","C8321-","T8322-","A8323-","G8324-","T8325-","T8326-","T8327-","T8328-","T8329-","A8330-","T8331-","C8332-","A8333-","G8334-","T8335-","G8336-","T8337-","C8338-","C8339-","T8340-","A8341-","T8342-","G8343-","C8344-","T8345-","A8346-","T8347-","A8348-","T8349-","T8350-","C8351-","C8352-","T8353-","G8354-","T8355-","T8356-","A8357-","T8358-","C8359-","A8360-","T8361-","C8362-","A8363-","T8364-","T8365-","A8366-","G8367-","T8368-","T8369-","A8370-","A8371-","T8372-","G8373-","A8374-","A8375-","A8376-","A8377-","T8378-","A8379-","A8380-","C8381-","T8382-","C8383-","T8384-","C8385-","G8386-","T8387-","G8388-","C8389-","T8390-","T8391-","C8392-","A8393-","G8394-","A8395-","A8396-","A8397-","A8398-","G8399-","T8400-","C8401-","A8402-","A8403-","A8404-","T8405-","A8406-","T8407-","T8408-","G8409-","T8410-","A8411-","T8412-","C8413-","C8414-","A8415-","T8416-","A8417-","C8418-","A8419-","T8420-","A8421-","T8422-","A8423-","T8424-","C8425-","T8426-","C8427-","C8428-","A8429-","A8430-","A8431-","A8432-","C8433-","T8434-","A8435-","T8436-","C8437-","A8438-","C8439-","T8440-","T8441-","A8442-","T8443-","A8444-","C8445-","G8446-","T8447-","T8448-","T8449-","A8450-","T8451-","C8452-","T8453-","T8454-","T8455-","A8456-","A8457-","C8458-","G8459-","A8460-","A8461-","C8462-","A8463-","T8464-","A8465-","T8466-","A8467-","C8468-","C8469-","T8470-","A8471-","G8472-","A8473-","T8474-","G8475-","G8476-","T8477-","T8478-","A8479-","T8480-","T8481-","T8482-","A8483-","C8484-","T8485-","A8486-","A8487-","C8488-","A8489-","G8490-","A8491-","C8492-","A8493-","T8494-","T8495-","T8496-","T8497-","T8498-","T8499-","C8500-","A8501-","A8502-","G8503-","A8504-","T8505-","C8506-","T8507-","A8508-","T8509-","T8510-","G8511-","A8512-","C8513-","A8514-","A8515-","T8516-","A8517-","A8518-","C8519-","T8520-","C8521-","C8522-","T8523-","A8524-","T8525-","A8526-","G8527-","T8528-","T8529-","T8530-","C8531-","C8532-","A8533-","C8534-","A8535-","T8536-","C8537-","A8538-","A8539-","C8540-","C8541-","A8542-","A8543-","G8544-","T8545-","A8546-","A8547-","T8548-","G8549-","A8550-","T8551-","C8552-","A8553-","T8554-","C8555-","T8556-","A8557-","T8558-","T8559-","G8560-","T8561-","T8562-","A8563-","T8564-","A8565-","T8566-","A8567-","A8568-","C8569-","A8570-","A8571-","T8572-","A8573-","A8574-","C8575-","A8576-","T8577-","A8578-","A8579-","C8580-","T8581-","C8582-","T8583-","T8584-","T8585-","T8586-","C8587-","C8588-","A8589-","T8590-","T8591-","T8592-","T8593-","T8594-","A8595-","T8596-","C8597-","A8598-","G8599-","T8600-","A8601-","T8602-","C8603-","T8604-","A8605-","T8606-","A8607-","T8608-","C8609-","A8610-","A8611-","C8612-","G8613-","T8614-","C8615-","G8616-","T8617-","T8618-","G8619-","T8620-","A8621-","G8622-","T8623-","G8624-","A8625-","A8626-","T8627-","A8628-","G8629-","T8630-","A8631-","G8632-","T8633-","C8634-","A8635-","T8636-","T8637-","G8638-","A8639-","T8640-","C8641-","T8642-","A8643-","T8644-","T8645-","A8646-","T8647-","A8648-","T8649-","G8650-","A8651-","A8652-","A8653-","C8654-","G8655-","G8656-","A8657-","T8658-","A8659-","T8660-","G8661-","T8662-","C8663-","T8664-","A8665-","G8666-","T8667-","T8668-","A8669-","A8670-","T8671-","A8672-","T8673-","T8674-","T8675-","T8676-","C8677-","T8678-","T8679-","T8680-","G8681-","A8682-","T8683-","T8684-","T8685-","A8686-","A8687-","A8688-","G8689-","T8690-","C8691-","T8692-","A8693-","T8694-","A8695-","G8696-","T8697-","C8698-","T8699-","T8700-","T8701-","A8702-","C8703-","A8704-","A8705-","A8706-","C8707-","A8708-","T8709-","A8710-","A8711-","T8712-","A8713-","T8714-","C8715-","C8716-","T8717-","T8718-","A8719-","T8720-","C8721-","C8722-","G8723-","A8724-","C8725-","T8726-","T8727-","T8728-","A8729-","T8730-","A8731-","T8732-","T8733-","T8734-","C8735-","C8736-","T8737-","G8738-","T8739-","A8740-","G8741-","G8742-","G8743-","T8744-","G8745-","G8746-","C8747-","A8748-","T8749-","A8750-","A8751-","T8752-","T8753-","T8754-","T8755-","A8756-","T8757-","T8758-","C8759-","T8760-","G8761-","C8762-","C8763-","T8764-","C8765-","C8766-","A8767-","C8768-","A8769-","A8770-","T8771-","C8772-","A8773-","G8774-","T8775-","G8776-","T8777-","T8778-","T8779-","C8780-","C8781-","A8782-","A8783-","A8784-","T8785-","A8786-","T8787-","A8788-","T8789-","T8790-","A8791-","C8792-","T8793-","A8794-","G8795-","A8796-","C8797-","A8798-","A8799-","T8800-","A8801-","T8802-","T8803-","C8804-","C8805-","A8806-","T8807-","A8808-","T8809-","A8810-","G8811-","T8812-","T8813-","A8814-","T8815-","T8816-","A8817-","G8818-","T8819-","T8820-","A8821-","A8822-","G8823-","G8824-","G8825-","A8826-","C8827-","C8828-","C8829-","A8830-","A8831-","T8832-","T8833-","A8834-","G8835-","A8836-","A8837-","C8838-","A8839-","C8840-","G8841-","T8842-","A8843-","C8844-","G8845-","C8846-","G8847-","C8848-","T8849-","T8850-","A8851-","T8852-","T8853-","C8854-","A8855-","T8856-","C8857-","A8858-","T8859-","T8860-","T8861-","G8862-","G8863-","A8864-","T8865-","C8866-","G8867-","T8868-","A8869-","T8870-","T8871-","T8872-","C8873-","A8874-","T8875-","A8876-","A8877-","A8878-","A8879-","G8880-","T8881-","T8882-","A8883-","T8884-","T8885-","A8886-","T8887-","G8888-","T8889-","T8890-","A8891-","T8892-","A8893-","G8894-","A8895-","T8896-","G8897-","T8898-","C8899-","A8900-","A8901-","C8902-","A8903-","C8904-","A8905-","T8906-","T8907-","C8908-","T8909-","A8910-","C8911-","A8912-","T8913-","T8914-","T8915-","T8916-","T8917-","T8918-","T8919-","A8920-","A8921-","T8922-","T8923-","G8924-","T8925-","C8926-","T8927-","A8928-","T8929-","A8930-","T8931-","A8932-","G8933-","T8934-","A8935-","T8936-","T8937-","T8938-","T8939-","T8940-","C8941-","T8942-","G8943-","A8944-","T8945-","A8946-","T8947-","T8948-","T8949-","T8950-","C8951-","T8952-","A8953-","T8954-","A8955-","A8956-","T8957-","A8958-","T8959-","C8960-","A8961-","G8962-","A8963-","A8964-","T8965-","T8966-","G8967-","T8968-","C8969-","T8970-","T8971-","C8972-","C8973-","A8974-","T8975-","A8976-","G8977-","G8978-","A8979-","A8980-","G8981-","T8982-","T8983-","G8984-","T8985-","A8986-","T8987-","A8988-","C8989-","T8990-","A8991-","T8992-","T8993-","C8994-","G8995-","G8996-","A8997-","A8998-","T8999-","C9000-","A9001-","G9002-","T9003-","T9004-","A9005-","C9006-","A9007-","T9008-","G9009-","T9010-","T9011-","T9012-","A9013-","A9014-","A9015-","T9016-","A9017-","A9018-","T9019-","T9020-","C9021-","T9022-","C9023-","T9024-","G9025-","A9026-","T9027-","G9028-","T9029-","C9030-","A9031-","T9032-","T9033-","C9034-","C9035-","T9036-","T9037-","A9038-","T9039-","A9040-","C9041-","A9042-","A9043-","T9044-","C9045-","A9046-","A9047-","A9048-","T9049-","T9050-","C9051-","A9052-","T9053-","T9054-","A9055-","T9056-","T9057-","A9058-","A9059-","A9060-","C9061-","A9062-","G9063-","T9064-","T9065-","T9066-","A9067-","A9068-","T9069-","A9070-","G9071-","T9072-","C9073-","T9074-","G9075-","T9076-","A9077-","G9078-","A9079-","C9080-","C9081-","T9082-","T9083-","T9084-","A9085-","T9086-","C9087-","G9088-","T9089-","C9090-","G9091-","T9092-","A9093-","C9094-","A9095-","T9096-","A9097-","T9098-","C9099-","C9100-","A9101-","T9102-","T9103-","G9104-","T9105-","C9106-","T9107-","T9108-","A9109-","T9110-","T9111-","A9112-","G9113-","T9114-","T9115-","A9116-","C9117-","G9118-","C9119-","T9120-","T9121-","A9122-","T9123-","T9124-","T9125-","T9126-","T9127-","A9128-","T9129-","G9130-","G9131-","G9132-","T9133-","T9134-","T9135-","T9136-","A9137-","C9138-","G9139-","T9140-","T9141-","G9142-","C9143-","T9144-","T9145-","T9146-","A9147-","T9148-","T9149-","A9150-","T9151-","A9152-","T9153-","T9154-","T9155-","T9156-","A9157-","T9158-","A9159-","A9160-","T9161-","A9162-","A9163-","T9164-","G9165-","A9166-","T9167-","T9168-","G9169-","T9170-","T9171-","T9172-","G9173-","A9174-","C9175-","A9176-","A9177-","T9178-","G9179-","T9180-","C9181-","G9182-","T9183-","A9184-","G9185-","T9186-","A9187-","T9188-","A9189-","G9190-","A9191-","T9192-","A9193-","T9194-","A9195-","T9196-","T9197-","A9198-","T9199-","T9200-","A9201-","G9202-","A9203-","G9204-","G9205-","A9206-","G9207-","G9208-","T9209-","A9210-","T9211-","A9212-","A9213-","T9214-","T9215-","A9216-","T9217-","A9218-","A9219-","A9220-","A9221-","A9222-","G9223-","T9224-","T9225-","T9226-","C9227-","T9228-","G9229-","A9230-","G9231-","T9232-","A9233-","C9234-","G9235-","A9236-","T9237-","G9238-","T9239-","T9240-","A9241-","T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","C9257-","A9258-","T9259-","T9260-","A9261-","A9262-","C9263-","A9264-","T9265-","C9266-","A9267-","T9268-","A9269-","C9270-","A9271-","T9272-","C9273-","A9274-","A9275-","T9276-","T9277-","A9278-","A9279-","C9280-","T9281-","A9282-","C9283-","A9284-","T9285-","T9286-","C9287-","T9288-","T9289-","A9290-","T9291-","A9292-","A9293-","C9294-","A9295-","T9296-","T9297-","G9298-","T9299-","A9300-","A9301-","T9302-","C9303-","A9304-","A9305-","A9306-","A9307-","G9308-","A9309-","A9310-","T9311-","T9312-","G9313-","C9314-","A9315-","A9316-","T9317-","T9318-","T9319-","T9320-","G9321-","A9322-","T9323-","G9324-","T9325-","A9326-","T9327-","A9328-","A9329-","C9330-","A9331-","A9332-","C9333-","T9334-","G9335-","T9336-","C9337-","A9338-","A9339-","T9340-","G9341-","G9342-","A9343-","A9344-","T9345-","T9346-","G9347-","T9348-","A9349-","T9350-","A9351-","T9352-","T9353-","A9354-","C9355-","A9356-","A9357-","A9358-","T9359-","T9360-","A9361-","C9362-","G9363-","G9364-","T9365-","A9366-","T9367-","G9368-","T9369-","T9370-","G9371-","T9372-","A9373-","A9374-","C9375-","A9376-","A9377-","C9378-","A9379-","A9380-","A9381-","T9382-","A9383-","C9384-","C9385-","G9386-","A9387-","T9388-","C9389-","G9390-","G9391-","T9392-","A9393-","A9394-","T9395-","T9396-","G9397-","T9398-","C9399-","T9400-","C9401-","T9402-","G9403-","C9404-","C9405-","G9406-","C9407-","T9408-","G9409-","T9410-","A9411-","A9412-","T9413-","A9414-","G9415-","A9416-","A9417-","T9418-","T9419-","A9420-","A9421-","T9422-","T9423-","A9424-","T9425-","A9426-","T9427-","A9428-","T9429-","C9430-","T9431-","A9432-","T9433-","T9434-","A9435-","C9436-","A9437-","C9438-","C9439-","G9440-","G9441-","C9442-","C9443-","T9444-","T9445-","G9446-","T9447-","A9448-","T9449-","C9450-","A9451-","T9452-","A9453-","A9454-","T9455-","A9456-","A9457-","A9458-","G9459-","T9460-","T9461-","G9462-","T9463-","G9464-","G9465-","T9466-","A9467-","G9468-","T9469-","A9470-","T9471-","G9472-","A9473-","T9474-","C9475-","T9476-","C9477-","C9478-","A9479-","T9480-","A9481-","T9482-","T9483-","T9484-","A9485-","T9486-","A9487-","A9488-","T9489-","T9490-","T9491-","A9492-","G9493-","T9494-","A9495-","C9496-","T9497-","T9498-","T9499-","G9500-","T9501-","A9502-","T9503-","T9504-","T9505-","A9506-","G9507-","T9508-","T9509-","T9510-","T9511-","T9512-","T9513-","T9514-","G9515-","G9516-","A9517-","A9518-","T9519-","C9520-","A9521-","T9522-","A9523-","A9524-","A9525-","A9526-","A9527-","A9528-","A9529-","G9530-","T9531-","T9532-","T9533-","T9534-","A9535-","C9536-","T9537-","A9538-","A9539-","T9540-","T9541-","T9542-","A9543-","A9544-","A9545-","A9546-","T9547-","T9548-","T9549-","A9550-","A9551-","A9552-","A9553-","A9554-","G9555-","T9556-","A9557-","T9558-","T9559-","T9560-","A9561-","C9562-","A9563-","T9564-","T9565-","T9566-","T9567-","T9568-","C9569-","A9570-","C9571-","T9572-","G9573-","T9574-","T9575-","T9576-","A9577-","G9578-","T9579-","C9580-","G9581-","C9582-","G9583-","G9584-","A9585-","T9586-","A9587-","T9588-","G9589-","G9590-","A9591-","A9592-","T9593-","T9594-","C9595-","G9596-","A9597-","T9598-","C9599-","C9600-","T9601-","G9602-","T9603-","C9604-","A9605-","A9606-","A9607-","A9608-","T9609-","C9610-","A9611-","A9612-","T9613-","A9614-","C9615-","A9616-","T9617-","C9618-","A9619-","T9620-","C9621-","T9622-","A9623-","T9624-","A9625-","G9626-","A9627-","T9628-","C9629-","A9630-","T9631-","G9632-","T9633-","A9634-","A9635-","C9636-","A9637-","A9638-","T9639-","A9640-","T9641-","T9642-","A9643-","C9644-","A9645-","A9646-","T9647-","A9648-","C9649-","A9650-","T9651-","A9652-","G9653-","A9654-","T9655-","G9656-","A9657-","A9658-","C9659-","C9660-","A9661-","A9662-","A9663-","T9664-","G9665-","A9666-","T9667-","A9668-","T9669-","A9670-","A9671-","G9672-","A9673-","C9674-","T9675-","A9676-","A9677-","C9678-","A9679-","G9680-","T9681-","A9682-","T9683-","G9684-","C9685-","A9686-","T9687-","T9688-","A9689-","T9690-","C9691-","C9692-","G9693-","A9694-","A9695-","A9696-","T9697-","G9698-","T9699-","T9700-","A9701-","A9702-","T9703-","A9704-","A9705-","C9706-","A9707-","T9708-","T9709-","A9710-","C9711-","A9712-","T9713-","A9714-","T9715-","T9716-","A9717-","T9718-","A9719-","T9720-","C9721-","A9722-","A9723-","T9724-","A9725-","T9726-","C9727-","A9728-","C9729-","A9730-","A9731-","A9732-","A9733-","A9734-","T9735-","A9736-","A9737-","A9738-","T9739-","C9740-","C9741-","A9742-","C9743-","A9744-","T9745-","T9746-","T9747-","G9748-","G9749-","C9750-","T9751-","A9752-","A9753-","T9754-","C9755-","G9756-","A9757-","T9758-","T9759-","T9760-","C9761-","G9762-","G9763-","G9764-","C9765-","T9766-","T9767-","G9768-","G9769-","A9770-","A9771-","A9772-","A9773-","A9774-","A9775-","C9776-","G9777-","T9778-","A9779-","T9780-","C9781-","G9782-","C9783-","C9784-","G9785-","G9786-","A9787-","A9788-","G9789-","G9790-","G9791-","A9792-","C9793-","T9794-","A9795-","T9796-","A9797-","T9798-","G9799-","A9800-","C9801-","T9802-","A9803-","A9804-","C9805-","T9806-","T9807-","A9808-","T9809-","C9810-","T9811-","A9812-","G9813-","A9814-","G9815-","A9816-","T9817-","A9818-","C9819-","A9820-","G9821-","G9822-","A9823-","A9824-","T9825-","A9826-","C9827-","A9828-","A9829-","C9830-","A9831-","A9832-","T9833-","C9834-","A9835-","A9836-","A9837-","A9838-","C9839-","T9840-","T9841-","A9842-","C9843-","T9844-","G9845-","A9846-","A9847-","A9848-","C9849-","T9850-","A9851-","T9852-","A9853-","C9854-","G9855-","T9856-","A9857-","A9858-","C9859-","T9860-","G9861-","T9862-","C9863-","A9864-","A9865-","A9866-","A9867-","A9868-","A9869-","A9870-","T9871-","A9872-","A9873-","A9874-","A9875-","A9876-","C9877-","A9878-","T9879-","A9880-","T9881-","A9882-","T9883-","G9884-","G9885-","T9886-","C9887-","T9888-","A9889-","T9890-","A9891-","T9892-","A9893-","T9894-","A9895-","C9896-","A9897-","C9898-","T9899-","A9900-","C9901-","A9902-","A9903-","T9904-","T9905-","T9906-","A9907-","G9908-","T9909-","T9910-","A9911-","T9912-","T9913-","A9914-","A9915-","T9916-","G9917-","T9918-","G9919-","G9920-","T9921-","T9922-","A9923-","T9924-","T9925-","G9926-","A9927-","T9928-","T9929-","G9930-","G9931-","A9932-","T9933-","A9934-","A9935-","C9936-","C9937-","G9938-","A9939-","T9940-","G9941-","T9942-","G9943-","A9944-","T9945-","T9946-","G9947-","T9948-","T9949-","C9950-","A9951-","A9952-","T9953-","C9954-","A9955-","A9956-","T9957-","A9958-","T9959-","T9960-","A9961-","A9962-","G9963-","A9964-","G9965-","G9966-","G9967-","T9968-","T9969-","G9970-","G9971-","T9972-","A9973-","A9974-","A9975-","T9976-","T9977-","G9978-","G9979-","T9980-","A9981-","C9982-","A9983-","T9984-","A9985-","G9986-","C9987-","T9988-","A9989-","A9990-","T9991-","A9992-","A9993-","T9994-","A9995-","C9996-","A9997-","T9998-","A9999-","T10000-","A10001-","C10002-","T10003-","C10004-","C10005-","A10006-","A10007-","A10008-","T10009-","A10010-","C10011-","A10012-","C10013-","C10014-","C10015-","A10016-","A10017-","T10018-","A10019-","A10020-","T10021-","A10022-","C10023-","T10024-","A10025-","C10026-","A10027-","A10028-","C10029-","C10030-","A10031-","T10032-","T10033-","T10034-","C10035-","T10036-","G10037-","A10038-","G10039-","T10040-","T10041-","G10042-","G10043-","A10044-","T10045-","A10046-","T10047-","C10048-","A10049-","T10050-","C10051-","A10052-","A10053-","A10054-","A10055-","T10056-","A10057-","C10058-","T10059-","G10060-","G10061-","A10062-","T10063-","A10064-","A10065-","A10066-","T10067-","A10068-","C10069-","G10070-","A10071-","G10072-","G10073-","A10074-","C10075-","A10076-","T10077-","G10078-","T10079-","A10080-","T10081-","A10082-","G10083-","A10084-","G10085-","T10086-","A10087-","A10088-","G10089-","T10090-","A10091-","A10092-","A10093-","G10094-","A10095-","A10096-","A10097-","A10098-","A10099-","G10100-","A10101-","A10102-","T10103-","G10104-","T10105-","G10106-","G10107-","A10108-","A10109-","T10110-","T10111-","T10112-","G10113-","C10114-","T10115-","A10116-","T10117-","G10118-","A10119-","A10120-","G10121-","T10122-","T10123-","G10124-","T10125-","T10126-","T10127-","A10128-","C10129-","T10130-","C10131-","A10132-","A10133-","A10134-","A10135-","C10136-","G10137-","A10138-","T10139-","T10140-","A10141-","G10142-","A10143-","A10144-","A10145-","A10146-","C10147-","G10148-","A10149-","T10150-","A10151-","G10152-","A10153-","T10154-","A10155-","C10156-","T10157-","T10158-","T10159-","G10160-","G10161-","T10162-","T10163-","T10164-","A10165-","T10166-","T10167-","G10168-","G10169-","A10170-","T10171-","T10172-","C10173-","G10174-","T10175-","G10176-","T10177-","A10178-","A10179-","T10180-","C10181-","A10182-","T10183-","A10184-","T10185-","A10186-","T10187-","T10188-","T10189-","T10190-","G10191-","C10192-","A10193-","T10194-","A10195-","A10196-","C10197-","A10198-","T10199-","G10200-","T10201-","A10202-","T10203-","C10204-","A10205-","A10206-","T10207-","A10208-","T10209-","A10210-","T10211-","G10212-","G10213-","C10214-","A10215-","T10216-","A10217-","G10218-","A10219-","A10220-","C10221-","A10222-","C10223-","G10224-","A10225-","A10226-","G10227-","A10228-","G10229-","A10230-","A10231-","A10232-","C10233-","C10234-","G10235-","G10236-","T10237-","G10238-","C10239-","G10240-","T10241-","C10242-","A10243-","G10244-","A10245-","T10246-","A10247-","A10248-","T10249-","T10250-","G10251-","T10252-","C10253-","C10254-","T10255-","A10256-","T10257-","A10258-","T10259-","G10260-","C10261-","C10262-","G10263-","T10264-","A10265-","C10266-","A10267-","C10268-","G10269-","T10270-","T10271-","T10272-","T10273-","A10274-","A10275-","A10276-","A10277-","A10278-","A10279-","A10280-","T10281-","A10282-","A10283-","C10284-","A10285-","A10286-","T10287-","G10288-","A10289-","G10290-","C10291-","A10292-","A10293-","G10294-","T10295-","T10296-","C10297-","T10298-","A10299-","T10300-","A10301-","A10302-","G10303-","C10304-","T10305-","A10306-","G10307-","T10308-","T10309-","A10310-","A10311-","C10312-","T10313-","A10314-","A10315-","T10316-","A10317-","A10318-","A10319-","T10320-","A10321-","A10322-","A10323-","A10324-","A10325-","G10326-","T10327-","T10328-","T10329-","A10330-","A10331-","T10332-","T10333-","A10334-","T10335-","C10336-","G10337-","A10338-","C10339-","G10340-","A10341-","T10342-","A10343-","T10344-","A10345-","T10346-","G10347-","T10348-","C10349-","G10350-","T10351-","T10352-","A10353-","T10354-","T10355-","T10356-","T10357-","T10358-","C10359-","T10360-","C10361-","T10362-","C10363-","A10364-","T10365-","A10366-","T10367-","G10368-","A10369-","A10370-","A10371-","G10372-","A10373-","T10374-","T10375-","A10376-","A10377-","T10378-","T10379-","T10380-","G10381-","A10382-","T10383-","T10384-","C10385-","T10386-","A10387-","A10388-","T10389-","A10390-","T10391-","A10392-","A10393-","T10394-","C10395-","T10396-","T10397-","C10398-","A10399-","G10400-","T10401-","A10402-","T10403-","T10404-","G10405-","G10406-","A10407-","T10408-","G10409-","A10410-","A10411-","T10412-","C10413-","T10414-","C10415-","A10416-","A10417-","T10418-","T10419-","C10420-","A10421-","A10422-","A10423-","T10424-","T10425-","A10426-","A10427-","T10428-","T10429-","C10430-","C10431-","A10432-","T10433-","T10434-","A10435-","G10436-","A10437-","T10438-","T10439-","A10440-","G10441-","A10442-","T10443-","T10444-","A10445-","G10446-","A10447-","T10448-","T10449-","A10450-","G10451-","A10452-","T10453-","C10454-","A10455-","T10456-","A10457-","A10458-","A10459-","T10460-","A10461-","A10462-","A10463-","A10464-","A10465-","T10466-","A10467-","G10468-","T10469-","A10470-","G10471-","C10472-","A10473-","C10474-","G10475-","C10476-","A10477-","C10478-","T10479-","A10480-","C10481-","T10482-","T10483-","C10484-","A10485-","G10486-","C10487-","C10488-","A10489-","A10490-","A10491-","T10492-","A10493-","T10494-","T10495-","C10496-","T10497-","T10498-","T10499-","T10500-","T10501-","T10502-","G10503-","A10504-","A10505-","A10506-","C10507-","G10508-","C10509-","C10510-","A10511-","T10512-","C10513-","T10514-","A10515-","G10516-","C10517-","G10518-","T10519-","A10520-","A10521-","T10522-","G10523-","A10524-","G10525-","A10526-","A10527-","C10528-","A10529-","C10530-","A10531-","A10532-","G10533-","T10534-","G10535-","A10536-","A10537-","C10538-","C10539-","T10540-","A10541-","T10542-","A10543-","A10544-","T10545-","G10546-","A10547-","G10548-","C10549-","A10550-","A10551-","A10552-","T10553-","T10554-","T10555-","A10556-","T10557-","T10558-","A10559-","G10560-","T10561-","A10562-","T10563-","C10564-","G10565-","G10566-","T10567-","T10568-","A10569-","C10570-","A10571-","T10572-","G10573-","A10574-","A10575-","G10576-","G10577-","A10578-","C10579-","T10580-","T10581-","T10582-","A10583-","C10584-","G10585-","T10586-","A10587-","G10588-","A10589-","G10590-","T10591-","G10592-","G10593-","T10594-","G10595-","A10596-","T10597-","T10598-","C10599-","C10600-","T10601-","C10602-","C10603-","A10604-","T10605-","C10606-","T10607-","G10608-","T10609-","G10610-","G10611-","T10612-","A10613-","C10614-","G10615-","A10616-","A10617-","C10618-","G10619-","G10620-","T10621-","T10622-","T10623-","C10624-","A10625-","T10626-","C10627-","T10628-","T10629-","C10630-","T10631-","T10632-","T10633-","G10634-","A10635-","T10636-","G10637-","C10638-","C10639-","A10640-","C10641-","C10642-","A10643-","C10644-","C10645-","C10646-","A10647-","G10648-","A10649-","T10650-","G10651-","T10652-","T10653-","C10654-","T10655-","A10656-","T10657-","A10658-","A10659-","A10660-","C10661-","T10662-","T10663-","G10664-","G10665-","T10666-","A10667-","T10668-","C10669-","C10670-","T10671-","C10672-","G10673-","T10674-","C10675-","C10676-","G10677-","A10678-","T10679-","T10680-","T10681-","C10682-","A10683-","T10684-","A10685-","T10686-","C10687-","A10688-","T10689-","T10690-","T10691-","G10692-","C10693-","C10694-","A10695-","A10696-","C10697-","C10698-","A10699-","A10700-","T10701-","A10702-","C10703-","A10704-","T10705-","A10706-","T10707-","A10708-","G10709-","C10710-","T10711-","A10712-","A10713-","A10714-","C10715-","C10716-","C10717-","A10718-","G10719-","G10720-","C10721-","A10722-","T10723-","A10724-","C10725-","G10726-","T10727-","T10728-","C10729-","C10730-","A10731-","C10732-","A10733-","C10734-","A10735-","T10736-","C10737-","C10738-","G10739-","G10740-","A10741-","A10742-","C10743-","A10744-","A10745-","T10746-","G10747-","A10748-","A10749-","A10750-","T10751-","T10752-","C10753-","T10754-","C10755-","C10756-","A10757-","G10758-","A10759-","A10760-","G10761-","A10762-","T10763-","G10764-","T10765-","T10766-","A10767-","C10768-","A10769-","A10770-","T10771-","G10772-","G10773-","C10774-","T10775-","A10776-","G10777-","A10778-","T10779-","T10780-","T10781-","G10782-","G10783-","A10784-","C10785-","A10786-","T10787-","T10788-","T10789-","G10790-","G10791-","T10792-","T10793-","T10794-","C10795-","A10796-","A10797-","C10798-","C10799-","G10800-","C10801-","G10802-","T10803-","T10804-","A10805-","A10806-","C10807-","A10808-","T10809-","A10810-","T10811-","G10812-","A10813-","G10814-","T10815-","G10816-","A10817-","A10818-","C10819-","A10820-","C10821-","A10822-","C10823-","C10824-","C10825-","A10826-","T10827-","A10828-","C10829-","A10830-","T10831-","G10832-","A10833-","A10834-","A10835-","G10836-","C10837-","G10838-","A10839-","T10840-","G10841-","A10842-","G10843-","A10844-","A10845-","A10846-","T10847-","A10848-","G10849-","G10850-","A10851-","T10852-","T10853-","C10854-","T10855-","C10856-","A10857-","T10858-","C10859-","T10860-","T10861-","G10862-","C10863-","C10864-","A10865-","A10866-","A10867-","A10868-","T10869-","A10870-","T10871-","C10872-","A10873-","C10874-","T10875-","A10876-","T10877-","A10878-","A10879-","A10880-","A10881-","A10882-","A10883-","T10884-","T10885-","T10886-","A10887-","T10888-","T10889-","T10890-","A10891-","T10892-","C10893-","A10894-","A10895-","T10896-","T10897-","T10898-","T10899-","A10900-","A10901-","A10902-","G10903-","G10904-","T10905-","A10906-","T10907-","A10908-","A10909-","A10910-","A10911-","A10912-","A10913-","A10914-","T10915-","A10916-","C10917-","T10918-","T10919-","A10920-","T10921-","T10922-","G10923-","T10924-","T10925-","G10926-","C10927-","T10928-","C10929-","G10930-","A10931-","A10932-","T10933-","A10934-","T10935-","T10936-","T10937-","T10938-","G10939-","T10940-","A10941-","T10942-","T10943-","T10944-","G10945-","A10946-","T10947-","G10948-","G10949-","T10950-","A10951-","T10952-","A10953-","C10954-","G10955-","G10956-","A10957-","A10958-","G10959-","A10960-","T10961-","T10962-","A10963-","G10964-","A10965-","A10966-","A10967-","T10968-","G10969-","T10970-","A10971-","G10972-","G10973-","T10974-","A10975-","T10976-","T10977-","A10978-","T10979-","C10980-","A10981-","T10982-","C10983-","A10984-","A10985-","C10986-","T10987-","G10988-","A10989-","T10990-","T10991-","T10992-","T10993-","A10994-","T10995-","G10996-","A10997-","T10998-","G10999-","G11000-","T11001-","T11002-","T11003-","T11004-","A11005-","T11006-","G11007-","A11008-","A11009-","T11010-","T11011-","T11012-","T11013-","A11014-","T11015-","T11016-","A11017-","T11018-","G11019-","C11020-","T11021-","T11022-","C11023-","A11024-","C11025-","T11026-","A11027-","T11028-","T11029-","G11030-","C11031-","A11032-","T11033-","C11034-","G11035-","G11036-","A11037-","A11038-","A11039-","T11040-","A11041-","A11042-","T11043-","A11044-","T11045-","C11046-","A11047-","T11048-","A11049-","T11050-","G11051-","C11052-","T11053-","T11054-","C11055-","C11056-","A11057-","C11058-","G11059-","T11060-","A11061-","T11062-","A11063-","T11064-","T11065-","T11066-","T11067-","A11068-","T11069-","T11070-","T11071-","T11072-","G11073-","T11074-","T11075-","T11076-","T11077-","G11078-","A11079-","C11080-","T11081-","C11082-","A11083-","T11084-","A11085-","A11086-","T11087-","A11088-","C11089-","G11090-","C11091-","A11092-","C11093-","G11094-","T11095-","A11096-","A11097-","T11098-","T11099-","C11100-","T11101-","G11102-","G11103-","A11104-","T11105-","T11106-","A11107-","T11108-","T11109-","G11110-","G11111-","C11112-","A11113-","T11114-","A11115-","T11116-","C11117-","G11118-","A11119-","T11120-","G11121-","A11122-","A11123-","T11124-","A11125-","A11126-","T11127-","T11128-","T11129-","T11130-","A11131-","G11132-","C11133-","T11134-","C11135-","C11136-","A11137-","T11138-","G11139-","C11140-","T11141-","C11142-","A11143-","G11144-","T11145-","A11146-","A11147-","A11148-","T11149-","A11150-","T11151-","T11152-","A11153-","A11154-","T11155-","G11156-","A11157-","G11158-","A11159-","A11160-","C11161-","A11162-","T11163-","A11164-","G11165-","T11166-","G11167-","T11168-","T11169-","G11170-","C11171-","C11172-","T11173-","C11174-","C11175-","T11176-","A11177-","C11178-","C11179-","A11180-","T11181-","T11182-","A11183-","T11184-","T11185-","T11186-","T11187-","T11188-","T11189-","T11190-","C11191-","A11192-","T11193-","C11194-","T11195-","C11196-","A11197-","T11198-","T11199-","C11200-","A11201-","A11202-","T11203-","T11204-","C11205-","T11206-","T11207-","G11208-","A11209-","T11210-","T11211-","G11212-","C11213-","A11214-","G11215-","A11216-","G11217-","A11218-","T11219-","C11220-","T11221-","A11222-","T11223-","A11224-","T11225-","A11226-","A11227-","T11228-","C11229-","A11230-","T11231-","T11232-","A11233-","T11234-","A11235-","G11236-","C11237-","G11238-","T11239-","T11240-","G11241-","A11242-","C11243-","T11244-","T11245-","A11246-","T11247-","G11248-","G11249-","A11250-","C11251-","T11252-","C11253-","T11254-","G11255-","G11256-","A11257-","A11258-","T11259-","C11260-","T11261-","T11262-","A11263-","G11264-","A11265-","C11266-","G11267-","A11268-","T11269-","G11270-","T11271-","A11272-","C11273-","A11274-","G11275-","T11276-","C11277-","A11278-","T11279-","C11280-","T11281-","A11282-","T11283-","A11284-","A11285-","T11286-","C11287-","A11288-","T11289-","G11290-","G11291-","T11292-","A11293-","T11294-","A11295-","T11296-","T11297-","T11298-","A11299-","A11300-","T11301-","A11302-","C11303-","A11304-","T11305-","T11306-","G11307-","T11308-","T11309-","T11310-","T11311-","A11312-","T11313-","A11314-","G11315-","C11316-","A11317-","T11318-","A11319-","G11320-","G11321-","C11322-","A11323-","T11324-","T11325-","A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","C11727T","C39139T","-173297T","-173298A","-173299T","-173314A","-173315T","-173316A","-173317T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A185259-","G185260-","A185261-","A185262-","T185263-","G185264-","T185265-","T185266-","T185267-","G185268-","C185269-","C185270-","A185271-","C185272-","A185273-","T185274-","T185275-","G185276-","G185277-","C185278-","T185279-","A185280-","G185281-","A185282-","G185283-","G185284-","A185285-","A185286-","T185287-","G185288-","C185289-","C185290-","G185291-","T185292-","T185293-","T185294-","A185295-","G185296-","A185297-","T185298-","C185299-","A185300-","A185301-","C185302-","G185303-","T185304-","A185305-","T185306-","T185307-","G185308-","C185309-","G185310-","A185311-","T185312-","A185313-","A185314-","C185315-","A185316-","G185317-","A185318-","C185319-","G185320-","A185321-","C185322-","G185323-","A185324-","T185325-","C185326-","A185327-","G185328-","G185329-","T185330-","T185331-","G185332-","T185333-","T185334-","A185335-","T185336-","T185337-","A185338-","T185339-","G185340-","C185341-","A185342-","G185343-","G185344-","A185345-","A185346-","T185347-","A185348-","C185349-","C185350-","A185351-","T185352-","T185353-","T185354-","C185355-","A185356-","T185357-","G185358-","A185359-","A185360-","G185361-","A185362-","T185363-","A185364-","G185365-","T185366-","G185367-","T185368-","A185369-","G185370-","A185371-","A185372-","A185373-","C185374-","A185375-","G185376-","A185377-","T185378-","A185379-","T185380-","A185381-","C185382-","A185383-","T185384-","T185385-","A185386-","T185387-","G185388-","G185389-","A185390-","C185391-","C185392-","A185393-","G185394-","A185395-","A185396-","A185397-","T185398-","A185399-","A185400-","T185401-","G185402-","T185403-","T185404-","A185405-","A185406-","A185407-","G185408-","G185409-","A185410-","A185411-","A185412-","C185413-","A185414-","T185415-","A185416-","T185417-","G185418-","A185419-","C185420-","A185421-","T185422-","A185423-","A185424-","A185425-","C185426-","A185427-","G185428-","T185429-","A185430-","T185431-","T185432-","G185433-","A185434-","C185435-","C185436-","C185437-","A185438-","C185439-","G185440-","A185441-","G185442-","T185443-","T185444-","A185445-","T185446-","A185447-","A185448-","C185449-","A185450-","A185451-","A185452-","G185453-","T185454-","C185455-","A185456-","A185457-","A185458-","G185459-","A185460-","C185461-","C185462-","C185463-","A185464-","T185465-","T185466-","T185467-","T185468-","C185469-","C185470-","T185471-","G185472-","C185473-","T185474-","C185475-","C185476-","A185477-","T185478-","T185479-","G185480-","A185481-","G185482-","T185483-","G185484-","T185485-","A185486-","A185487-","A185488-","A185489-","T185490-","T185491-","C185492-","A185493-","T185494-","G185495-","G185496-","T185497-","T185498-","G185499-","A185500-","C185501-","A185502-","A185503-","T185504-","T185505-","T185506-","A185507-","G185508-","G185509-","A185510-","A185511-","A185512-","T185513-","G185514-","G185515-","A185516-","T185517-","A185518-","T185519-","G185520-","A185521-","C185522-","A185523-","A185524-","C185525-","C185526-","C185527-","T185528-","A185529-","A185530-","T185531-","T185532-","C185533-","A185534-","T185535-","T185536-","T185537-","T185538-","G185539-","G185540-","G185541-","A185542-","A185543-","G185544-","A185545-","T185546-","G185547-","C185548-","T185549-","A185550-","A185551-","A185552-","A185553-","C185554-","T185555-","A185556-","A185557-","G185558-","A185559-","A185560-","A185561-","C185562-","G185563-","G185564-","A185565-","C185566-","A185567-","T185568-","A185569-","T185570-","A185571-","G185572-","T185573-","G185574-","C185575-","A185576-","A185577-","T185578-","G185579-","A185580-","C185581-","G185582-","A185583-","T185584-","A185585-","A185586-","A185587-","A185588-","G185589-","T185590-","C185591-","C185592-","T185593-","A185594-","C185595-","C185596-","A185597-","T185598-","G185599-","T185600-","A185601-","C185602-","A185603-","G185604-","T185605-","G185606-","A185607-","G185608-","A185609-","A185610-","A185611-","T185612-","A185613-","A185614-","A185615-","A185616-","A185617-","T185618-","A185619-","T185620-","A185621-","G185622-","A185623-","C185624-","T185625-","T185626-","T185627-","G185628-","G185629-","A185630-","T185631-","A185632-","T185633-","A185634-","A185635-","C185636-","T185637-","A185638-","T185639-","G185640-","G185641-","A185642-","G185643-","A185644-","T185645-","A185646-","T185647-","T185648-","A185649-","T185650-","T185651-","T185652-","C185653-","T185654-","A185655-","A185656-","T185657-","A185658-","T185659-","G185660-","G185661-","T185662-","T185663-","T185664-","A185665-","T185666-","C185667-","T185668-","A185669-","C185670-","A185671-","A185672-","T185673-","C185674-","T185675-","A185676-","C185677-","T185678-","A185679-","G185680-","T185681-","C185682-","A185683-","G185684-","G185685-","A185686-","T185687-","T185688-","A185689-","T185690-","G185691-","G185692-","A185693-","G185694-","A185695-","T185696-","G185697-","G185698-","T185699-","A185700-","C185701-","C185702-","A185703-","A185704-","A185705-","T185706-","A185707-","T185708-","A185709-","C185710-","A185711-","T185712-","T185713-","T185714-","A185715-","A185716-","A185717-","T185718-","C185719-","C185720-","G185721-","T185722-","A185723-","A185724-","C185725-","T185726-","A185727-","G185728-","A185729-","T185730-","C185731-","A185732-","G185733-","A185734-","T185735-","C185736-","A185737-","T185738-","G185739-","A185740-","G185741-","T185742-","G185743-","T185744-","G185745-","A185746-","A185747-","T185748-","C185749-","T185750-","A185751-","G185752-","C185753-","T185754-","T185755-","A185756-","G185757-","A185758-","T185759-","C185760-","T185761-","A185762-","A185763-","C185764-","G185765-","T185766-","C185767-","T185768-","A185769-","A185770-","G185771-","G185772-","A185773-","A185774-","G185775-","T185776-","A185777-","A185778-","C185779-","T185780-","G185781-","T185782-","G185783-","A185784-","C185785-","A185786-","T185787-","G185788-","T185789-","C185790-","C185791-","T185792-","G185793-","C185794-","G185795-","T185796-","T185797-","T185798-","A185799-","G185800-","T185801-","A185802-","T185803-","A185804-","C185805-","C185806-","A185807-","A185808-","G185809-","A185810-","A185811-","A185812-","T185813-","A185814-","T185815-","A185816-","T185817-","C185818-","A185819-","A185820-","C185821-","A185822-","T185823-","A185824-","T185825-","G185826-","A185827-","A185828-","G185829-","G185830-","T185831-","C185832-","T185833-","A185834-","T185835-","G185836-","C185837-","T185838-","T185839-","T185840-","A185841-","G185842-","T185843-","G185844-","T185845-","T185846-","A185847-","C185848-","T185849-","A185850-","C185851-","A185852-","T185853-","C185854-","T185855-","A185856-","A185857-","A185858-","G185859-","A185860-","T185861-","C185862-","A185863-","T185864-","T185865-","G185866-","T185867-","G185868-","C185869-","T185870-","A185871-","C185872-","A185873-","G185874-","G185875-","T185876-","A185877-","T185878-","T185879-","G185880-","G185881-","T185882-","T185883-","G185884-","G185885-","T185886-","T185887-","A185888-","A185889-","A185890-","A185891-","T185892-","C185893-","T185894-","A185895-","G185896-","T185897-","G185898-","G185899-","T185900-","T185901-","A185902-","T185903-","G185904-","G185905-","G185906-","A185907-","A185908-","G185909-","G185910-","A185911-","A185912-","G185913-","A185914-","T185915-","G185916-","C185917-","T185918-","G185919-","A185920-","T185921-","A185922-","A185923-","A185924-","C185925-","C185926-","A185927-","C185928-","G185929-","T185930-","G185931-","C185932-","T185933-","T185934-","G185935-","T185936-","T185937-","T185938-","T185939-","C185940-","A185941-","T185942-","C185943-","A185944-","T185945-","T185946-","G185947-","G185948-","A185949-","A185950-","T185951-","T185952-","A185953-","T185954-","T185955-","A185956-","C185957-","A185958-","C185959-","A185960-","C185961-","T185962-","G185963-","T185964-","C185965-","G185966-","T185967-","T185968-","G185969-","G185970-","A185971-","T185972-","T185973-","A185974-","T185975-","T185976-","A185977-","C185978-","T185979-","G185980-","T185981-","T185982-","C185983-","A185984-","T185985-","A185986-","C185987-","G185988-","A185989-","A185990-","G185991-","A185992-","T185993-","A185994-","T185995-","T185996-","T185997-","G185998-","G185999-","A186000-","G186001-","A186002-","A186003-","G186004-","C186005-","A186006-","C186007-","C186008-","T186009-","G186010-","G186011-","C186012-","C186013-","T186014-","G186015-","A186016-","C186017-","T186018-","A186019-","T186020-","G186021-","A186022-","T186023-","C186024-","C186025-","A186026-","T186027-","G186028-","T186029-","A186030-","A186031-","G186032-","T186033-","C186034-","A186035-","T186036-","A186037-","T186038-","A186039-","T186040-","C186041-","C186042-","A186043-","T186044-","A186045-","T186046-","A186047-","G186048-","A186049-","G186050-","T186051-","A186052-","T186053-","A186054-","G186055-","A186056-","G186057-","A186058-","T186059-","A186060-","C186061-","A186062-","T186063-","G186064-","G186065-","A186066-","T186067-","A186068-","G186069-","A186070-","A186071-","T186072-","C186073-","T186074-","A186075-","A186076-","T186077-","G186078-","T186079-","G186080-","T186081-","T186082-","A186083-","C186084-","A186085-","G186086-","C186087-","A186088-","A186089-","C186090-","C186091-","T186092-","C186093-","C186094-","T186095-","T186096-","A186097-","C186098-","A186099-","C186100-","A186101-","T186102-","T186103-","C186104-","G186105-","A186106-","A186107-","T186108-","T186109-","C186110-","A186111-","T186112-","T186113-","C186114-","A186115-","T186116-","G186117-","A186118-","C186119-","A186120-","A186121-","T186122-","T186123-","C186124-","T186125-","A186126-","A186127-","C186128-","G186129-","A186130-","A186131-","T186132-","A186133-","T186134-","G186135-","T186136-","G186137-","G186138-","A186139-","T186140-","A186141-","A186142-","A186143-","G186144-","A186145-","A186146-","A186147-","T186148-","T186149-","A186150-","G186151-","T186152-","A186153-","A186154-","C186155-","A186156-","A186157-","A186158-","T186159-","T186160-","A186161-","A186162-","A186163-","T186164-","G186165-","A186166-","T186167-","C186168-","T186169-","G186170-","T186171-","A186172-","C186173-","A186174-","A186175-","T186176-","G186177-","A186178-","A186179-","T186180-","A186181-","C186182-","A186183-","A186184-","G186185-","A186186-","A186187-","G186188-","A186189-","T186190-","T186191-","A186192-","T186193-","G186194-","G186195-","A186196-","A186197-","T186198-","A186199-","T186200-","A186201-","G186202-","C186203-","G186204-","A186205-","C186206-","G186207-","G186208-","A186209-","T186210-","C186211-","A186212-","T186213-","T186214-","G186215-","C186216-","C186217-","G186218-","G186219-","C186220-","G186221-","T186222-","C186223-","T186224-","A186225-","T186226-","A186227-","A186228-","A186229-","C186230-","A186231-","G186232-","A186233-","T186234-","T186235-","A186236-","G186237-","C186238-","A186239-","A186240-","A186241-","G186242-","G186243-","C186244-","A186245-","T186246-","T186247-","G186248-","A186249-","C186250-","T186251-","T186252-","C186253-","A186254-","G186255-","A186256-","G186257-","G186258-","G186259-","T186260-","A186261-","G186262-","A186263-","G186264-","A186265-","A186266-","A186267-","T186268-","A186269-","G186270-","C186271-","A186272-","A186273-","G186274-","T186275-","G186276-","T186277-","T186278-","A186279-","A186280-","T186281-","A186282-","T186283-","A186284-","G186285-","A186286-","T186287-","G186288-","G186289-","T186290-","A186291-","A186292-","T186293-","C186294-","T186295-","G186296-","T186297-","T186298-","A186299-","G186300-","A186301-","T186302-","A186303-","T186304-","C186305-","G186306-","C186307-","A186308-","T186309-","A186310-","T186311-","C186312-","A186313-","A186314-","G186315-","C186316-","A186317-","G186318-","A186319-","T186320-","A186321-","A186322-","G186323-","G186324-","A186325-","A186326-","A186327-","A186328-","G186329-","A186330-","T186331-","G186332-","G186333-","C186334-","C186335-","G186336-","A186337-","C186338-","A186339-","T186340-","A186341-","C186342-","A186343-","G186344-","A186345-","C186346-","A186347-","A186348-","G186349-","A186350-","A186351-","T186352-","A186353-","A186354-","A186355-","T186356-","G186357-","A186358-","T186359-","A186360-","T186361-","T186362-","A186363-","T186364-","T186365-","A186366-","G186367-","A186368-","G186369-","A186370-","T186371-","T186372-","T186373-","G186374-","T186375-","T186376-","T186377-","A186378-","T186379-","A186380-","C186381-","A186382-","C186383-","A186384-","C186385-","T186386-","C186387-","T186388-","A186389-","T186390-","C186391-","A186392-","G186393-","A186394-","C186395-","A186396-","A186397-","A186398-","G186399-","A186400-","T186401-","A186402-","T186403-","A186404-","A186405-","A186406-","A186407-","G186408-","A186409-","C186410-","A186411-","T186412-","T186413-","A186414-","T186415-","A186416-","G186417-","A186418-","A186419-","T186420-","C186421-","C186422-","G186423-","A186424-","A186425-","G186426-","A186427-","A186428-","G186429-","G186430-","T186431-","A186432-","A186433-","G186434-","A186435-","G186436-","A186437-","T186438-","G186439-","T186440-","T186441-","G186442-","T186443-","A186444-","T186445-","A186446-","A186447-","T186448-","A186449-","G186450-","A186451-","T186452-","G186453-","T186454-","T186455-","A186456-","A186457-","G186458-","A186459-","A186460-","C186461-","A186462-","A186463-","T186464-","C186465-","T186466-","T186467-","G186468-","T186469-","T186470-","A186471-","A186472-","A186473-","A186474-","A186475-","G186476-","T186477-","A186478-","C186479-","T186480-","A186481-","T186482-","T186483-","C186484-","T186485-","A186486-","T186487-","T186488-","G186489-","A186490-","T186491-","A186492-","A186493-","T186494-","T186495-","A186496-","T186497-","C186498-","T186499-","A186500-","T186501-","G186502-","T186503-","G186504-","A186505-","T186506-","A186507-","C186508-","T186509-","T186510-","T186511-","A186512-","G186513-","A186514-","T186515-","G186516-","A186517-","T186518-","T186519-","A186520-","T186521-","A186522-","T186523-","A186524-","T186525-","A186526-","C186527-","A186528-","C186529-","C186530-","T186531-","C186532-","T186533-","G186534-","T186535-","A186536-","G186537-","A186538-","A186539-","T186540-","A186541-","T186542-","A186543-","A186544-","C186545-","A186546-","A186547-","A186548-","T186549-","C186550-","C186551-","T186552-","A186553-","T186554-","G186555-","T186556-","G186557-","T186558-","T186559-","A186560-","G186561-","T186562-","A186563-","A186564-","A186565-","C186566-","G186567-","A186568-","T186569-","A186570-","C186571-","T186572-","T186573-","A186574-","T186575-","A186576-","T186577-","G186578-","A186579-","G186580-","C186581-","T186582-","A186583-","T186584-","G186585-","A186586-","C186587-","T186588-","A186589-","T186590-","C186591-","T186592-","T186593-","G186594-","A186595-","A186596-","T186597-","C186598-","A186599-","T186600-","C186601-","A186602-","G186603-","G186604-","T186605-","G186606-","T186607-","A186608-","G186609-","T186610-","T186611-","G186612-","T186613-","T186614-","C186615-","T186616-","A186617-","T186618-","C186619-","A186620-","T186621-","G186622-","T186623-","T186624-","A186625-","T186626-","G186627-","A186628-","A186629-","A186630-","T186631-","G186632-","A186633-","C186634-","T186635-","A186636-","T186637-","A186638-","A186639-","T186640-","C186641-","T186642-","C186643-","C186644-","T186645-","T186646-","G186647-","G186648-","A186649-","T186650-","A186651-","C186652-","A186653-","A186654-","A186655-","A186656-","G186657-","A186658-","C186659-","G186660-","C186661-","C186662-","A186663-","A186664-","A186665-","G186666-","A186667-","T186668-","G186669-","C186670-","T186671-","A186672-","T186673-","A186674-","G186675-","A186676-","A186677-","G186678-","A186679-","T186680-","G186681-","T186682-","G186683-","A186684-","T186685-","A186686-","G186687-","T186688-","A186689-","G186690-","C186691-","A186692-","A186693-","G186694-","T186695-","G186696-","C186697-","G186698-","G186699-","T186700-","A186701-","G186702-","C186703-","C186704-","G186705-","A186706-","A186707-","G186708-","C186709-","A186710-","T186711-","T186712-","G186713-","A186714-","A186715-","T186716-","G186717-","A186718-","C186719-","A186720-","T186721-","G186722-","T186723-","T186724-","T186725-","A186726-","A186727-","G186728-","G186729-","A186730-","A186731-","T186732-","T186733-","T186734-","G186735-","A186736-","T186737-","A186738-","A186739-","A186740-","A186741-","A186742-","C186743-","G186744-","T186745-","A186746-","A186747-","G186748-","T186749-","G186750-","C186751-","T186752-","A186753-","T186754-","T186755-","A186756-","T186757-","A186758-","A186759-","T186760-","A186761-","A186762-","A186763-","A186764-","G186765-","A186766-","A186767-","G186768-","A186769-","A186770-","G186771-","A186772-","T186773-","A186774-","A186775-","T186776-","T186777-","A186778-","T186779-","C186780-","T186781-","A186782-","A186783-","A186784-","C186785-","A186786-","G186787-","T186788-","T186789-","C186790-","G186791-","C186792-","C186793-","C186794-","G186795-","A186796-","T186797-","A186798-","T186799-","C186800-","T186801-","A186802-","C186803-","C186804-","A186805-","T186806-","A186807-","T186808-","A186809-","A186810-","T186811-","A186812-","T186813-","A186814-","T186815-","A186816-","T186817-","C186818-","A186819-","T186820-","A186821-","G186822-","G186823-","T186824-","G186825-","G186826-","C186827-","A186828-","C186829-","T186830-","A186831-","T186832-","T186833-","C186834-","T186835-","G186836-","C186837-","T186838-","A186839-","C186840-","T186841-","G186842-","T186843-","T186844-","A186845-","G186846-","T186847-","C186848-","A186849-","T186850-","T186851-","A186852-","T186853-","T186854-","T186855-","T186856-","A186857-","A186858-","T186859-","A186860-","T186861-","T186862-","G186863-","G186864-","C186865-","A186866-","A186867-","T186868-","T186869-","T186870-","A186871-","T186872-","A186873-","T186874-","A186875-","G186876-","C186877-","G186878-","C186879-","G186880-","C186881-","A186882-","A186883-","T186884-","A186885-","A186886-","A186887-","T186888-","A186889-","C186890-","A186891-","G186892-","A186893-","A186894-","C186895-","C186896-","A186897-","G186898-","G186899-","A186900-","A186901-","A186902-","T186903-","A186904-","T186905-","G186906-","A186907-","A186908-","A186909-","T186910-","A186911-","A186912-","T186913-","G186914-","A186915-","A186916-","A186917-","T186918-","A186919-","T186920-","G186921-","A186922-","C186923-","A186924-","A186925-","T186926-","A186927-","T186928-","G186929-","A186930-","G186931-","C186932-","A186933-","T186934-","T186935-","A186936-","A186937-","A186938-","T186939-","C186940-","T186941-","G186942-","A186943-","G186944-","C186945-","A186946-","T186947-","C186948-","A186949-","T186950-","G186951-","A186952-","T186953-","A186954-","G186955-","T186956-","C186957-","T186958-","T186959-","G186960-","A186961-","A186962-","A186963-","C186964-","A186965-","G186966-","T186967-","G186968-","T186969-","C186970-","T186971-","A186972-","T186973-","G186974-","G186975-","A186976-","A186977-","A186978-","T186979-","T186980-","A186981-","T186982-","T186983-","G186984-","A186985-","T186986-","A186987-","A186988-","T186989-","C186990-","G186991-","G186992-","T186993-","A186994-","C186995-","T186996-","A186997-","A186998-","T186999-","A187000-","A187001-","A187002-","A187003-","T187004-","A187005-","G187006-","T187007-","T187008-","T187009-","A187010-","A187011-","C187012-","T187013-","C187014-","T187015-","T187016-","T187017-","T187018-","A187019-","G187020-","A187021-","A187022-","C187023-","C187024-","A187025-","G187026-","T187027-","T187028-","T187029-","G187030-","G187031-","T187032-","A187033-","C187034-","T187035-","G187036-","T187037-","A187038-","A187039-","T187040-","T187041-","T187042-","C187043-","A187044-","G187045-","T187046-","T187047-","C187048-","A187049-","T187050-","T187051-","A187052-","C187053-","T187054-","C187055-","G187056-","T187057-","T187058-","G187059-","A187060-","G187061-","A187062-","A187063-","T187064-","A187065-","T187066-","T187067-","G187068-","A187069-","T187070-","G187071-","A187072-","T187073-","T187074-","T187075-","T187076-","T187077-","T187078-","T187079-","T187080-","A187081-","A187082-","A187083-","T187084-","G187085-","A187086-","G187087-","T187088-","A187089-","T187090-","C187091-","G187092-","G187093-","T187094-","A187095-","G187096-","T187097-","T187098-","A187099-","C187100-","A187101-","T187102-","A187103-","T187104-","T187105-","A187106-","C187107-","C187108-","A187109-","T187110-","A187111-","T187112-","C187113-","A187114-","T187115-","C187116-","C187117-","A187118-","T187119-","T187120-","A187121-","T187122-","A187123-","T187124-","A187125-","A187126-","T187127-","C187128-","G187129-","A187130-","T187131-","G187132-","A187133-","T187134-","G187135-","C187136-","A187137-","T187138-","G187139-","T187140-","A187141-","T187142-","T187143-","A187144-","G187145-","A187146-","A187147-","T187148-","A187149-","C187150-","T187151-","T187152-","T187153-","C187154-","C187155-","G187156-","A187157-","A187158-","T187159-","A187160-","A187161-","G187162-","T187163-","C187164-","T187165-","T187166-","C187167-","T187168-","A187169-","A187170-","A187171-","T187172-","A187173-","T187174-","T187175-","G187176-","T187177-","A187178-","T187179-","T187180-","A187181-","A187182-","T187183-","T187184-","A187185-","T187186-","G187187-","A187188-","A187189-","A187190-","A187191-","A187192-","C187193-","T187194-","A187195-","T187196-","G187197-","C187198-","T187199-","A187200-","T187201-","G187202-","T187203-","G187204-","A187205-","G187206-","T187207-","A187208-","T187209-","G187210-","A187211-","T187212-","T187213-","C187214-","A187215-","A187216-","A187217-","G187218-","A187219-","T187220-","G187221-","T187222-","T187223-","T187224-","A187225-","A187226-","T187227-","G187228-","A187229-","T187230-","A187231-","C187232-","G187233-","A187234-","T187235-","A187236-","C187237-","T187238-","A187239-","G187240-","A187241-","T187242-","T187243-","T187244-","T187245-","A187246-","T187247-","C187248-","T187249-","C187250-","T187251-","A187252-","G187253-","C187254-","G187255-","A187256-","G187257-","A187258-","T187259-","T187260-","G187261-","T187262-","T187263-","T187264-","A187265-","G187266-","A187267-","A187268-","T187269-","C187270-","A187271-","T187272-","T187273-","T187274-","A187275-","T187276-","C187277-","A187278-","T187279-","A187280-","A187281-","C187282-","T187283-","A187284-","T187285-","G187286-","T187287-","T187288-","T187289-","A187290-","A187291-","T187292-","A187293-","A187294-","A187295-","T187296-","T187297-","C187298-","A187299-","T187300-","C187301-","A187302-","A187303-","C187304-","G187305-","A187306-","A187307-","T187308-","A187309-","T187310-","C187311-","G187312-","A187313-","T187314-","A187315-","A187316-","A187317-","G187318-","A187319-","C187320-","C187321-","T187322-","C187323-","T187324-","T187325-","G187326-","T187327-","A187328-","A187329-","T187330-","T187331-","C187332-","G187333-","A187334-","G187335-","T187336-","A187337-","T187338-","A187339-","G187340-","G187341-","A187342-","A187343-","G187344-","T187345-","A187346-","G187347-","T187348-","A187349-","T187350-","T187351-","A187352-","C187353-","C187354-","A187355-","T187356-","A187357-","T187358-","C187359-","A187360-","A187361-","C187362-","T187363-","T187364-","C187365-","C187366-","G187367-","A187368-","G187369-","T187370-","T187371-","A187372-","A187373-","C187374-","A187375-","A187376-","T187377-","T187378-","A187379-","C187380-","T187381-","C187382-","T187383-","A187384-","A187385-","A187386-","A187387-","C187388-","A187389-","T187390-","G187391-","A187392-","G187393-","G187394-","A187395-","T187396-","T187397-","G187398-","T187399-","A187400-","C187401-","T187402-","C187403-","C187404-","T187405-","G187406-","T187407-","C187408-","T187409-","T187410-","T187411-","A187412-","T187413-","T187414-","G187415-","G187416-","A187417-","G187418-","A187419-","T187420-","C187421-","A187422-","C187423-","T187424-","A187425-","T187426-","T187427-","T187428-","A187429-","G187430-","T187431-","C187432-","G187433-","T187434-","T187435-","G187436-","A187437-","T187438-","A187439-","A187440-","A187441-","C187442-","T187443-","A187444-","G187445-","T187446-","A187447-","A187448-","C187449-","C187450-","T187451-","C187452-","A187453-","G187454-","G187455-","T187456-","T187457-","T187458-","C187459-","T187460-","T187461-","T187462-","A187463-","C187464-","A187465-","A187466-","A187467-","C187468-","G187469-","A187470-","T187471-","A187472-","A187473-","A187474-","G187475-","T187476-","A187477-","C187478-","A187479-","A187480-","C187481-","A187482-","T187483-","C187484-","A187485-","A187486-","G187487-","A187488-","C187489-","C187490-","T187491-","C187492-","A187493-","C187494-","A187495-","A187496-","C187497-","A187498-","C187499-","A187500-","G187501-","T187502-","G187503-","C187504-","A187505-","A187506-","G187507-","A187508-","T187509-","T187510-","A187511-","A187512-","T187513-","C187514-","T187515-","A187516-","G187517-","A187518-","A187519-","A187520-","T187521-","C187522-","A187523-","A187524-","A187525-","T187526-","G187527-","T187528-","A187529-","A187530-","T187531-","T187532-","C187533-","T187534-","G187535-","G187536-","A187537-","G187538-","G187539-","A187540-","G187541-","A187542-","A187543-","T187544-","C187545-","T187546-","A187547-","G187548-","A187549-","C187550-","A187551-","A187552-","C187553-","T187554-","A187555-","A187556-","C187557-","A187558-","C187559-","C187560-","C187561-","A187562-","C187563-","G187564-","G187565-","C187566-","G187567-","A187568-","A187569-","G187570-","T187571-","A187572-","T187573-","A187574-","C187575-","T187576-","T187577-","T187578-","A187579-","T187580-","G187581-","C187582-","C187583-","T187584-","C187585-","A187586-","T187587-","T187588-","C187589-","A187590-","G187591-","A187592-","A187593-","A187594-","C187595-","G187596-","G187597-","T187598-","A187599-","A187600-","C187601-","T187602-","G187603-","T187604-","A187605-","G187606-","T187607-","A187608-","G187609-","G187610-","A187611-","G187612-","A187613-","C187614-","T187615-","G187616-","T187617-","C187618-","T187619-","C187620-","T187621-","C187622-","T187623-","A187624-","A187625-","T187626-","C187627-","T187628-","C187629-","G187630-","A187631-","T187632-","G187633-","T187634-","A187635-","T187636-","A187637-","T187638-","A187639-","T187640-","A187641-","A187642-","T187643-","A187644-","T187645-","A187646-","T187647-","A187648-","C187649-","C187650-","A187651-","A187652-","T187653-","A187654-","C187655-","G187656-","G187657-","A187658-","C187659-","G187660-","C187661-","G187662-","A187663-","T187664-","A187665-","T187666-","A187667-","T187668-","T187669-","C187670-","C187671-","G187672-","A187673-","C187674-","A187675-","T187676-","G187677-","A187678-","A187679-","T187680-","G187681-","G187682-","C187683-","G187684-","T187685-","C187686-","G187687-","C187688-","T187689-","T187690-","A187691-","T187692-","C187693-","A187694-","T187695-","A187696-","T187697-","G187698-","T187699-","T187700-","A187701-","T187702-","A187703-","T187704-","C187705-","C187706-","T187707-","A187708-","A187709-","A187710-","T187711-","G187712-","T187713-","T187714-","G187715-","A187716-","T187717-","C187718-","A187719-","T187720-","A187721-","T187722-","T187723-","C187724-","C187725-","A187726-","C187727-","A187728-","A187729-","A187730-","T187731-","G187732-","A187733-","T187734-","T187735-","G187736-","T187737-","G187738-","A187739-","A187740-","C187741-","G187742-","A187743-","G187744-","A187745-","T187746-","T187747-","A187748-","A187749-","A187750-","T187751-","C187752-","A187753-","T187754-","C187755-","T187756-","A187757-","A187758-","C187759-","A187760-","A187761-","A187762-","T187763-","A187764-","A187765-","T187766-","T187767-","A187768-","G187769-","T187770-","T187771-","T187772-","T187773-","T187774-","T187775-","A187776-","T187777-","G187778-","A187779-","C187780-","A187781-","T187782-","T187783-","A187784-","A187785-","C187786-","A187787-","T187788-","A187789-","T187790-","A187791-","A187792-","T187793-","A187794-","A187795-","A187796-","T187797-","A187798-","A187799-","A187800-","T187801-","T187802-","A187803-","A187804-","T187805-","C187806-","A187807-","T187808-","T187809-","A187810-","T187811-","T187812-","G187813-","A187814-","C187815-","T187816-","T187817-","A187818-","A187819-","C187820-","G187821-","A187822-","T187823-","G187824-","A187825-","C187826-","G187827-","A187828-","A187829-","A187830-","G187831-","T187832-","T187833-","A187834-","T187835-","C187836-","A187837-","T187838-","T187839-","A187840-","T187841-","C187842-","T187843-","T187844-","A187845-","G187846-","G187847-","A187848-","T187849-","T187850-","C187851-","T187852-","T187853-","G187854-","A187855-","T187856-","T187857-","A187858-","T187859-","T187860-","A187861-","A187862-","T187863-","A187864-","C187865-","A187866-","A187867-","A187868-","T187869-","T187870-","C187871-","G187872-","T187873-","T187874-","G187875-","T187876-","G187877-","T187878-","C187879-","T187880-","A187881-","T187882-","G187883-","A187884-","A187885-","A187886-","T187887-","G187888-","T187889-","G187890-","A187891-","A187892-","C187893-","A187894-","A187895-","G187896-","G187897-","T187898-","G187899-","T187900-","C187901-","T187902-","C187903-","A187904-","T187905-","A187906-","T187907-","T187908-","A187909-","T187910-","A187911-","A187912-","T187913-","G187914-","C187915-","A187916-","C187917-","A187918-","A187919-","G187920-","A187921-","A187922-","T187923-","T187924-","A187925-","A187926-","A187927-","G187928-","T187929-","G187930-","T187931-","T187932-","G187933-","T187934-","A187935-","A187936-","A187937-","C187938-","T187939-","A187940-","T187941-","C187942-","T187943-","A187944-","G187945-","C187946-","C187947-","A187948-","G187949-","G187950-","A187951-","A187952-","C187953-","A187954-","T187955-","A187956-","T187957-","T187958-","C187959-","A187960-","G187961-","A187962-","T187963-","T187964-","A187965-","T187966-","C187967-","G187968-","A187969-","T187970-","G187971-","T187972-","G187973-","A187974-","T187975-","A187976-","A187977-","A187978-","T187979-","A187980-","C187981-","A187982-","G187983-","C187984-","G187985-","A187986-","T187987-","A187988-","C187989-","C187990-","A187991-","T187992-","C187993-","T187994-","G187995-","T187996-","G187997-","G187998-","A187999-","C188000-","A188001-","T188002-","T188003-","G188004-","T188005-","C188006-","C188007-","A188008-","A188009-","G188010-","T188011-","G188012-","A188013-","C188014-","A188015-","C188016-","A188017-","T188018-","T188019-","C188020-","A188021-","C188022-","G188023-","T188024-","C188025-","A188026-","A188027-","T188028-","A188029-","T188030-","A188031-","T188032-","A188033-","A188034-","T188035-","C188036-","G188037-","T188038-","T188039-","C188040-","T188041-","C188042-","C188043-","T188044-","C188045-","G188046-","G188047-","T188048-","G188049-","T188050-","C188051-","A188052-","T188053-","A188054-","G188055-","T188056-","T188057-","G188058-","T188059-","A188060-","G188061-","A188062-","G188063-","G188064-","T188065-","C188066-","A188067-","C188068-","A188069-","C188070-","C188071-","T188072-","T188073-","G188074-","T188075-","A188076-","C188077-","A188078-","C188079-","C188080-","T188081-","A188082-","C188083-","C188084-","A188085-","C188086-","A188087-","A188088-","A188089-","T188090-","A188091-","G188092-","A188093-","A188094-","T188095-","A188096-","T188097-","G188098-","T188099-","C188100-","A188101-","T188102-","T188103-","G188104-","T188105-","G188106-","A188107-","C188108-","T188109-","C188110-","G188111-","A188112-","A188113-","T188114-","A188115-","G188116-","T188117-","T188118-","A188119-","T188120-","C188121-","G188122-","T188123-","C188124-","T188125-","C188126-","C188127-","T188128-","T188129-","A188130-","A188131-","A188132-","G188133-","C188134-","T188135-","T188136-","C188137-","T188138-","G188139-","A188140-","T188141-","G188142-","G188143-","T188144-","A188145-","A188146-","C188147-","T188148-","G188149-","T188150-","G188151-","T188152-","T188153-","A188154-","C188155-","A188156-","T188157-","G188158-","T188159-","G188160-","C188161-","T188162-","C188163-","C188164-","T188165-","A188166-","A188167-","A188168-","A188169-","C188170-","A188171-","A188172-","A188173-","A188174-","T188175-","A188176-","T188177-","G188178-","G188179-","T188180-","C188181-","G188182-","T188183-","G188184-","T188185-","G188186-","T188187-","A188188-","C188189-","G188190-","G188191-","A188192-","A188193-","A188194-","G188195-","A188196-","A188197-","A188198-","G188199-","G188200-","A188201-","G188202-","A188203-","A188204-","A188205-","A188206-","T188207-","G188208-","A188209-","T188210-","A188211-","T188212-","G188213-","G188214-","A188215-","A188216-","T188217-","A188218-","C188219-","C188220-","A188221-","T188222-","T188223-","T188224-","G188225-","T188226-","A188227-","A188228-","G188229-","A188230-","A188231-","A188232-","T188233-","G188234-","T188235-","C188236-","G188237-","G188238-","A188239-","A188240-","G188241-","G188242-","G188243-","T188244-","A188245-","C188246-","T188247-","T188248-","A188249-","T188250-","T188251-","C188252-","A188253-","G188254-","A188255-","T188256-","A188257-","T188258-","T188259-","G188260-","T188261-","A188262-","T188263-","C188264-","T188265-","G188266-","A188267-","C188268-","T188269-","C188270-","T188271-","G188272-","A188273-","T188274-","C188275-","A188276-","A188277-","T188278-","G188279-","T188280-","A188281-","A188282-","A188283-","C188284-","C188285-","T188286-","A188287-","T188288-","G188289-","A188290-","C188291-","A188292-","A188293-","G188294-","A188295-","T188296-","A188297-","A188298-","G188299-","A188300-","C188301-","T188302-","T188303-","A188304-","C188305-","T188306-","C188307-","G188308-","C188309-","A188310-","T188311-","C188312-","T188313-","A188314-","C188315-","T188316-","G188317-","G188318-","A188319-","T188320-","A188321-","G188322-","A188323-","C188324-","A188325-","T188326-","A188327-","A188328-","A188329-","T188330-","A188331-","T188332-","C188333-","C188334-","T188335-","C188336-","C188337-","T188338-","C188339-","G188340-","T188341-","A188342-","A188343-","T188344-","A188345-","A188346-","T188347-","G188348-","A188349-","A188350-","A188351-","T188352-","A188353-","T188354-","A188355-","A188356-","T188357-","A188358-","T188359-","A188360-","C188361-","A188362-","C188363-","T188364-","A188365-","A188366-","T188367-","T188368-","A188369-","T188370-","T188371-","A188372-","A188373-","T188374-","A188375-","T188376-","C188377-","A188378-","A188379-","T188380-","C188381-","G188382-","A188383-","G188384-","T188385-","A188386-","T188387-","T188388-","A188389-","A188390-","C188391-","A188392-","T188393-","A188394-","T188395-","A188396-","A188397-","G188398-","T188399-","T188400-","A188401-","T188402-","T188403-","T188404-","T188405-","T188406-","A188407-","A188408-","A188409-","C188410-","C188411-","C188412-","C188413-","T188414-","T188415-","T188416-","T188417-","G188418-","G188419-","G188420-","T188421-","T188422-","C188423-","C188424-","G188425-","T188426-","C188427-","C188428-","T188429-","A188430-","A188431-","A188432-","C188433-","G188434-","G188435-","C188436-","G188437-","T188438-","T188439-","T188440-","C188441-","G188442-","G188443-","T188444-","C188445-","T188446-","G188447-","T188448-","G188449-","T188450-","C188451-","G188452-","C188453-","C188454-","A188455-","C188456-","C188457-","A188458-","T188459-","G188460-","G188461-","T188462-","C188463-","A188464-","C188465-","A188466-","C188467-","C188468-","G188469-","A188470-","G188471-","C188472-","C188473-","T188474-","C188475-","T188476-","G188477-","C188478-","G188479-","T188480-","G188481-","C188482-","T188483-","C188484-","C188485-","T188486-","C188487-","C188488-","A188489-","T188490-","C188491-","G188492-","A188493-","G188494-","G188495-","A188496-","C188497-","G188498-","A188499-","C188500-","T188501-","T188502-","C188503-","A188504-","A188505-","C188506-","T188507-","A188508-","T188509-","G188510-","A188511-","C188512-","A188513-","G188514-","C188515-","T188516-","C188517-","G188518-","G188519-","T188520-","G188521-","G188522-","C188523-","G188524-","T188525-","C188526-","T188527-","G188528-","C188529-","C188530-","A188531-","G188532-","C188533-","G188534-","T188535-","G188536-","T188537-","A188538-","C188539-","A188540-","T188541-","A188542-","C188543-","G188544-","A188545-","A188546-","T188547-","G188548-","G188549-","C188550-","A188551-","T188552-","T188553-","T188554-","C188555-","T188556-","A188557-","A188558-","G188559-","A188560-","A188561-","A188562-","A188563-","G188564-","T188565-","C188566-","T188567-","A188568-","C188569-","G188570-","G188571-","T188572-","A188573-","T188574-","C188575-","C188576-","T188577-","T188578-","T188579-","C188580-","T188581-","A188582-","C188583-","A188584-","A188585-","T188586-","T188587-","T188588-","C188589-","C188590-","T188591-","T188592-","T188593-","A188594-","A188595-","C188596-","A188597-","A188598-","C188599-","G188600-","G188601-","C188602-","A188603-","A188604-","C188605-","A188606-","G188607-","C188608-","T188609-","G188610-","C188611-","A188612-","G188613-","T188614-","A188615-","T188616-","T188617-","T188618-","T188619-","T188620-","A188621-","T188622-","A188623-","C188624-","T188625-","T188626-","T188627-","G188628-","A188629-","A188630-","T188631-","G188632-","C188633-","A188634-","T188635-","C188636-","G188637-","G188638-","A188639-","C188640-","A188641-","T188642-","T188643-","T188644-","A188645-","T188646-","A188647-","C188648-","A188649-","A188650-","G188651-","G188652-","G188653-","A188654-","G188655-","T188656-","C188657-","C188658-","T188659-","G188660-","T188661-","T188662-","C188663-","T188664-","A188665-","A188666-","T188667-","A188668-","T188669-","T188670-","G188671-","G188672-","C188673-","A188674-","T188675-","C188676-","A188677-","A188678-","T188679-","G188680-","T188681-","T188682-","C188683-","G188684-","G188685-","A188686-","T188687-","C188688-","T188689-","A188690-","T188691-","A188692-","G188693-","G188694-","C188695-","T188696-","T188697-","G188698-","A188699-","T188700-","T188701-","T188702-","T188703-","C188704-","G188705-","C188706-","A188707-","T188708-","T188709-","G188710-","A188711-","C188712-","T188713-","T188714-","T188715-","A188716-","C188717-","A188718-","C188719-","A188720-","G188721-","A188722-","C188723-","A188724-","T188725-","G188726-","A188727-","A188728-","C188729-","A188730-","T188731-","C188732-","C188733-","C188734-","C188735-","T188736-","G188737-","A188738-","A188739-","T188740-","C188741-","T188742-","G188743-","T188744-","A188745-","C188746-","A188747-","T188748-","A188749-","C188750-","T188751-","T188752-","T188753-","G188754-","T188755-","G188756-","G188757-","A188758-","T188759-","T188760-","T188761-","A188762-","C188763-","A188764-","C188765-","T188766-","G188767-","T188768-","T188769-","A188770-","G188771-","A188772-","A188773-","T188774-","C188775-","T188776-","C188777-","T188778-","A188779-","A188780-","C188781-","G188782-","C188783-","T188784-","G188785-","G188786-","C188787-","C188788-","T188789-","C188790-","T188791-","G188792-","T188793-","T188794-","G188795-","T188796-","T188797-","A188798-","C188799-","T188800-","T188801-","T188802-","C188803-","T188804-","A188805-","T188806-","G188807-","A188808-","T188809-","G188810-","C188811-","A188812-","C188813-","G188814-","T188815-","A188816-","T188817-","C188818-","G188819-","T188820-","T188821-","A188822-","T188823-","G188824-","C188825-","A188826-","A188827-","G188828-","C188829-","T188830-","T188831-","T188832-","C188833-","A188834-","T188835-","G188836-","T188837-","T188838-","G188839-","A188840-","C188841-","T188842-","A188843-","C188844-","T188845-","G188846-","C188847-","A188848-","G188849-","T188850-","G188851-","T188852-","T188853-","T188854-","C188855-","T188856-","T188857-","G188858-","C188859-","T188860-","C188861-","T188862-","G188863-","A188864-","C188865-","T188866-","A188867-","C188868-","A188869-","T188870-","A188871-","T188872-","A188873-","C188874-","T188875-","C188876-","T188877-","A188878-","C188879-","A188880-","A188881-","T188882-","C188883-","A188884-","A188885-","A188886-","G188887-","A188888-","G188889-","A188890-","G188891-","A188892-","T188893-","T188894-","T188895-","C188896-","A188897-","G188898-","T188899-","A188900-","A188901-","A188902-","C188903-","T188904-","T188905-","G188906-","T188907-","A188908-","A188909-","C188910-","A188911-","G188912-","G188913-","A188914-","T188915-","T188916-","G188917-","T188918-","T188919-","T188920-","G188921-","C188922-","T188923-","G188924-","C188925-","T188926-","T188927-","T188928-","C188929-","T188930-","G188931-","G188932-","A188933-","T188934-","-196616A"],"OPG023":["D392N"],"OPG057":["E353K"]},"labels":{"aa":"OPG023: D392N; OPG057: E353K"}}},{"name":"OP612688","node_attrs":{"div":522,"accession":"OP612688","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/104/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-11-02"},"strain_display":{"value":"Nigeria/OP612688/2019-11-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","G1126A","G2039A","G2152A","C6948T","C47224T","T76087-","C77726T","C143845T","G152431A","C166786T","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","G184037T","C184535T","C195058T","C195171T","C196084T"],"OPG002":["S238L"],"OPG002_dup":["S238L"],"OPG066":["E69K"],"OPG099":["S21F"],"OPG192":["S19L"]},"labels":{"aa":"OPG002: S238L; OPG002_dup: S238L; OPG066: E69K; OPG099: S21F; OPG192: S19L"}}},{"name":"OP612681","node_attrs":{"div":520,"accession":"OP612681","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/039/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-04-20"},"strain_display":{"value":"Nigeria/OP612681/2019-04-20"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["A1231G","G22971A","G23711A","G33177A","T76087-","G77635A","C83496T","C90945T","T121121-","G138571A","A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","T187080-"],"OPG098":["D246N"],"OPG156":["T280I"]},"labels":{"aa":"OPG098: D246N; OPG156: T280I"}}},{"name":"OP612674","node_attrs":{"div":518,"accession":"OP612674","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/003/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-01-12"},"strain_display":{"value":"Nigeria/OP612674/2019-01-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C11555T","G28645A","G75967A","T76087-","G94840A","A173292-","T173293-","A173294-","T173295-","A173296-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","C188503T","A196612-","A196613-","A196614-","A196615-"],"OPG023":["R449Q"],"OPG115":["E61K"]},"labels":{"aa":"OPG023: R449Q; OPG115: E61K"}}},{"name":"NODE_0000084","node_attrs":{"div":514,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G151929A","-196616A"],"OPG178":["E141K"]},"labels":{"aa":"OPG178: E141K"}},"children":[{"name":"OL504742","node_attrs":{"div":521,"accession":"OL504742","author":{"author":"Atkinson,B.,Pottage,T.,Ngabo,D.,Crook,A.,Pitman,J.,Summers,S.,Pullan,S.,Lewandowski,K.,Furneaux,J.,Davies,K.,Brooks,T.","value":"Atkinson,B.,Pottage,T.,Ngabo,D.,Crook,A.,Pitman,J.,Summers,S.,Pullan,S.,Lewandowski,K.,Furneaux,J.,Davies,K.,Brooks,T."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"2095"},"date":{"value":"2019-12-XX"},"strain_display":{"value":"United Kingdom/OL504742/2019-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C13065T","C29887T","G61329A","C72206T","G103431A","C165369T","-173314A","-173315T","-173316A","-173317T","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G188949A","T192184C"],"OPG024":["G55E"],"OPG092":["E248K"],"OPG123":["S547L"],"OPG190":["S83F"]},"labels":{"aa":"OPG024: G55E; OPG092: E248K; OPG123: S547L; OPG190: S83F"}}},{"name":"NODE_0000085","node_attrs":{"div":515,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C39767T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A"]}},"children":[{"name":"MT903342","node_attrs":{"div":517,"accession":"MT903342","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"Singapore"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-Singapore"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-05-XX"},"strain_display":{"value":"Singapore/MT903342/2019-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["-608T","C43927T","C170573T","-173297T","-173298A","-173299T","-173314A","-173315T","-173316A","-173317T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"],"OPG064":["E658K"],"OPG198":["S179L"]},"labels":{"aa":"OPG064: E658K; OPG198: S179L"}}},{"name":"OP612685","node_attrs":{"div":515,"accession":"OP612685","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/052/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-05-29"},"strain_display":{"value":"Nigeria/OP612685/2019-05-29"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-","A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","-196617A"]}}}]}]},{"name":"NODE_0000086","node_attrs":{"div":515,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G25661A","C39119T","-173297T","-173298A","-173299T","-173314A","-173315T","-173316A","-173317T"]}},"children":[{"name":"OP612679","node_attrs":{"div":523,"accession":"OP612679","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/018/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-03-14"},"strain_display":{"value":"Nigeria/OP612679/2019-03-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["C8500T","G79538A","G81354A","G84416A","C88736T","G100642A","C138791T","C161616T","-196616A","-196617A"],"OPG102":["D152N"],"OPG105":["E77K"],"OPG109":["E238K"],"OPG119":["R86K"],"OPG156":["D207N"]},"labels":{"aa":"OPG102: D152N; OPG105: E77K; OPG109: E238K; OPG119: R86K; OPG156: D207N"}}},{"name":"NODE_0000087","node_attrs":{"div":516,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T607-","G162243A","A196615-"]}},"children":[{"name":"MT903345","node_attrs":{"div":516,"accession":"MT903345","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"United Kingdom"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-UK_P3"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-09-XX"},"strain_display":{"value":"United Kingdom/MT903345/2018-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"MT903344","node_attrs":{"div":516,"accession":"MT903344","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"country":{"value":"United Kingdom"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-UK_P2"},"host":{"value":"Homo sapiens"},"date":{"value":"2018-09-XX"},"strain_display":{"value":"United Kingdom/MT903344/2018-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"]}}},{"name":"NODE_0000088","node_attrs":{"div":519,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G1262A","C3818T","G124130A","C128698T","T133102-","T133177-","C133178-","T133179-","T133180-","T133181-","C133182-","T133183-","C133184-","A133185-","A133186-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179177T","-179178A","G193392A","C195948T"],"OPG001":["S105L"],"OPG001_dup":["S105L"],"OPG003":["D264N"],"OPG003_dup":["D264N"],"OPG145":["E62K"],"OPG150":["S307L"]},"labels":{"aa":"OPG001: S105L; OPG001_dup: S105L; OPG003: D264N; OPG003_dup: D264N; OPG145: E62K; OPG150: S307L"}},"children":[{"name":"OP612687","node_attrs":{"div":524,"accession":"OP612687","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/058/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-07-11"},"strain_display":{"value":"Nigeria/OP612687/2019-07-11"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","C756T","G2039A","G168365A","A173288-","T173289-","-179172C","-179173A","-179174T","-179175T","-179176A","C188605A","A188606C","G188607A","T193455A","C195171T","G196454-","A196614-"],"OPG002":["S238L"],"OPG002_dup":["S238L"],"OPG003_dup":["L285I"],"OPG195":["E46K"]},"labels":{"aa":"OPG002: S238L; OPG002_dup: S238L; OPG003_dup: L285I; OPG195: E46K"}}},{"name":"NODE_0000089","node_attrs":{"div":520,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G81275A"]}},"children":[{"name":"OP612686","node_attrs":{"div":521,"accession":"OP612686","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/053/19"},"host":{"value":"Homo sapiens"},"date":{"value":"2019-06-26"},"strain_display":{"value":"Nigeria/OP612686/2019-06-26"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["-607T","T76087-","G88640A","-179172C","-179173A","-179174T","-179175T","-179176A","-196615A","-196616A","-196617A"],"OPG109":["R270C"]},"labels":{"aa":"OPG109: R270C"}}},{"name":"NODE_0000090","node_attrs":{"div":545,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G2591A","G3522A","C7771T","G14000T","G15428A","G21723A","G30367A","G31053A","G34459A","G37202A","G38360A","C38662T","G52885A","G54117A","G54635A","G64297A","C73066T","C82373T","G82451A","G95034A","G124674A","-133102T","C162331T","-173290A","-173291T","-173292A","-173293T","-173294A","-173295T","-173296A","-173297T","-173298A","-173299T","-173300A","-173301T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","G178133A","G181980A","G186578A","C193688T","C194619T"],"OPG002":["S54F"],"OPG002_dup":["S54F"],"OPG025":["A423D"],"OPG047":["R48C"],"OPG053":["P78S"],"OPG056":["E125K"],"OPG071":["L108F"],"OPG072":["D56N"],"OPG093":["S30L"],"OPG145":["R243Q"],"OPG210":["D209N","M1741I"]},"labels":{"aa":"OPG002: S54F; OPG002_dup: S54F; OPG025: A423D; OPG047: R48C; OPG053: P78S; OPG056: E125K; OPG071: L108F; OPG072: D56N; OPG093: S30L; OPG145: R243Q; OPG210: D209N, M1741I","clade":"A.1.1"}},"children":[{"name":"ON676708","node_attrs":{"div":548,"accession":"ON676708","author":{"author":"Gigante,C.M.,Myers,R.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Blythe,D.,Li,Y.","value":"Gigante,C.M.,Myers,R.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Blythe,D.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"A.1.1"},"strain":{"value":"MPXV_USA_2021_MD"},"host":{"value":"Homo sapiens"},"date":{"value":"2021-11-XX"},"strain_display":{"value":"USA/ON676708/2021-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C79348T","C86979T","C133714T","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"NODE_0000091","node_attrs":{"div":556,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G3111A","C39139T","G73239A","G74205A","G77383A","C84587T","C150469T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A151461C","G155795A","G170262A","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C183519T","C194099T"],"OPG057":["E353K"],"OPG093":["D88N"],"OPG094":["M142I"],"OPG098":["E162K"],"OPG176":["H221Y"],"OPG210":["P722S"]},"labels":{"aa":"OPG057: E353K; OPG093: D88N; OPG094: M142I; OPG098: E162K; OPG176: H221Y; OPG210: P722S","clade":"B.1"}},"children":[{"name":"LC722946","node_attrs":{"div":559,"accession":"LC722946","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"country":{"value":"Japan"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/TKY220091/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Japan/LC722946/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["C13653T","C116100T","G150376A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG025":["D539N"],"OPG176":["D190N"]},"labels":{"aa":"OPG025: D539N; OPG176: D190N"}}},{"name":"OP160532","node_attrs":{"div":557,"accession":"OP160532","author":{"author":"Tutu van Furth AM,van der Kuip M,van Els AL,Fievez LC,van Rijckevorsel GG,van den Ouden A,Jonges M,Welkers MR,Welkers,M.,Jonges,M.","value":"Tutu van Furth AM,van der Kuip M,van Els AL,Fievez LC,van Rijckevorsel GG,van den Ouden A,Jonges M,Welkers MR,Welkers,M.,Jonges,M."},"country":{"value":"Netherlands"},"institution":{"value":"Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Netherlands/NH-AUMC-0001/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Netherlands/OP160532/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A148207T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G191845A","A196614-"],"OPG173":["E57D"]},"labels":{"aa":"OPG173: E57D"}}},{"name":"OP133006","node_attrs":{"div":560,"accession":"OP133006","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"country":{"value":"Austria"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV/Austria/MUW1532243/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-06"},"strain_display":{"value":"Austria/OP133006/2022-07-06"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A28532-","C122511T","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","G151801A","C153984T","G169886A","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG044":["M148-"],"OPG143":["E269K"],"OPG178":["G98E"],"OPG197":["E73K"]},"labels":{"aa":"OPG044: M148-; OPG143: E269K; OPG178: G98E; OPG197: E73K"}}},{"name":"OP062230","node_attrs":{"div":557,"accession":"OP062230","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Jolly,G.,Griffiths,E.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Jolly,G.,Griffiths,E.,Charest,H.,Levade,I.,Fafard,J."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3864/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-22"},"strain_display":{"value":"Canada/OP062230/2022-06-22"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C57790T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG077":["R265K"]},"labels":{"aa":"OPG077: R265K"}}},{"name":"OP019275","node_attrs":{"div":559,"accession":"OP019275","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"country":{"value":"Austria"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV/Austria/MUW1525179/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-10"},"strain_display":{"value":"Austria/OP019275/2022-06-10"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","A107070C","C144546T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G190319A","-196615A","-196616A","-196617A"],"OPG166":["S50F"]},"labels":{"aa":"OPG166: S50F"}}},{"name":"ON959134","node_attrs":{"div":557,"accession":"ON959134","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_USA_2022_NY003"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/ON959134/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C98368T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON927243","node_attrs":{"div":557,"accession":"ON927243","author":{"author":"Palomino-Cabrera,R.,Penas-Utrilla,D.,Buenestado-Serrano,S.,Perez-Lago,L.,Herranz Martin,M.,Veintimilla,C.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Palomino-Cabrera,R.,Penas-Utrilla,D.,Buenestado-Serrano,S.,Perez-Lago,L.,Herranz Martin,M.,Veintimilla,C.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"country":{"value":"Spain"},"institution":{"value":"HGUGM, Microbial Genomics"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MpxV/Spain/MD-HGUGM-6642566/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-21"},"strain_display":{"value":"Spain/ON927243/2022-06-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","C187154T"]}}},{"name":"ON880524","node_attrs":{"div":556,"accession":"ON880524","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3080/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-26"},"strain_display":{"value":"Canada/ON880524/2022-05-26"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"ON838940","node_attrs":{"div":556,"accession":"ON838940","author":{"author":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J.","value":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J."},"country":{"value":"Spain"},"institution":{"value":"Hospital Universitario La Paz, Microbiology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"4061"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-20"},"strain_display":{"value":"Spain/ON838940/2022-05-20"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON872184","node_attrs":{"div":561,"accession":"ON872184","author":{"author":"Fletcher,N.,Gonzalez,G.,Meredith,L.,Purves,K.,Carr,M.,Dean,J.,Keogan,B.,Crowley,B.,Lyons,F.,O'Reilly,S.,Gautier,V.,Mallon,P.,Gordon,S.,Connell,J.,De Gascun,C.F.","value":"Fletcher,N.,Gonzalez,G.,Meredith,L.,Purves,K.,Carr,M.,Dean,J.,Keogan,B.,Crowley,B.,Lyons,F.,O'Reilly,S.,Gautier,V.,Mallon,P.,Gordon,S.,Connell,J.,De Gascun,C.F."},"country":{"value":"Ireland"},"institution":{"value":"University College Dublin, National Virus Reference Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"WA-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Ireland/ON872184/2022-05-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T48785C","G49636A","C50017T","T72809C","G178541A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG068":["G479E"],"OPG069":["T11I"],"OPG092":["K47E"]},"labels":{"aa":"OPG068: G479E; OPG069: T11I; OPG092: K47E"}}},{"name":"ON751962","node_attrs":{"div":559,"accession":"ON751962","author":{"author":"Claro,I.M.,de Lima,E.L.,Romano,C.M.,Candido,D.S.,Lindoso,J.A.L.,Barra,L.A.C.,Borges,L.M.S.,Medeiros,L.A.,Tomishige,M.Y.S.,Ramundo,M.S.,Moutinho,T.,da Silva,A.J.D.,Rodrigues,C.C.M.,de Azevedo,L.C.F.,Villas-Boas,L.S.,da Silva,C.A.M.,Coletti,T.M.,O'Toole,A.,Quick,J.,Loman,N.,Rambaut,A.,Faria,N.R.,Figueiredo-Mello,C.,Sabino,E.C.","value":"Claro,I.M.,de Lima,E.L.,Romano,C.M.,Candido,D.S.,Lindoso,J.A.L.,Barra,L.A.C.,Borges,L.M.S.,Medeiros,L.A.,Tomishige,M.Y.S.,Ramundo,M.S.,Moutinho,T.,da Silva,A.J.D.,Rodrigues,C.C.M.,de Azevedo,L.C.F.,Villas-Boas,L.S.,da Silva,C.A.M.,Coletti,T.M.,O'Toole,A.,Quick,J.,Loman,N.,Rambaut,A.,Faria,N.R.,Figueiredo-Mello,C.,Sabino,E.C."},"country":{"value":"Brazil"},"institution":{"value":"Imperial College London, School of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/BR0001/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-07"},"strain_display":{"value":"Brazil/ON751962/2022-06-07"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G10118A","C15004T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G169928A","G173575-","A173576-","G173577-","A173578-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG021":["E178K"],"OPG197":["D87N"]},"labels":{"aa":"OPG021: E178K; OPG197: D87N"}}},{"name":"ON649710","node_attrs":{"div":556,"accession":"ON649710","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0027/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-18"},"strain_display":{"value":"Portugal/ON649710/2022-05-18"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"ON619836","node_attrs":{"div":558,"accession":"ON619836","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"Research & Evaluation, UKHSA, UK"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_UK_2022_2"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"United Kingdom/ON619836/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C7259T","C33832T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG052":["R55Q"]},"labels":{"aa":"OPG052: R55Q"}}},{"name":"ON622713","node_attrs":{"div":557,"accession":"ON622713","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"Microbiology, Immunology & Transplantation, KU Leuven, Rega Institute, Belgium"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPX/UZ_REGA_2/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-22"},"strain_display":{"value":"Belgium/ON622713/2022-05-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C4629T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G192581A"]}}},{"name":"ON614676","node_attrs":{"div":556,"accession":"ON614676","author":{"author":"Gruber,C.E.M.,Rueca,M.,Gramigna,G.,Carletti,F.,Butera,O.,Fabeni,L.,Specchiarello,E.,Meschi,S.,Colavita,F.,Minosse,C.,Francalancia,M.,Lapa,D.,Garbuglia,A.R.,Giombini,E.","value":"Gruber,C.E.M.,Rueca,M.,Gramigna,G.,Carletti,F.,Butera,O.,Fabeni,L.,Specchiarello,E.,Meschi,S.,Colavita,F.,Minosse,C.,Francalancia,M.,Lapa,D.,Garbuglia,A.R.,Giombini,E."},"country":{"value":"Italy"},"institution":{"value":"Laboratory of Virology, INMI Lazzaro Spallanzani IRCCS, Italy"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"INMI-Pt1"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-18"},"strain_display":{"value":"Italy/ON614676/2022-05-18"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"ON615424","node_attrs":{"div":558,"accession":"ON615424","author":{"author":"Oude Munnink,B.B.,Boter,M.,Wellers,B.,Molenkamp,R.,Sikkema,R.S.,Koopmans,M.","value":"Oude Munnink,B.B.,Boter,M.,Wellers,B.,Molenkamp,R.,Sikkema,R.S.,Koopmans,M."},"country":{"value":"Netherlands"},"institution":{"value":"Public Health Virology, Erasmus Medical Centre, The Netherlands"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_2022_NL001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Netherlands/ON615424/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155611A","G171003A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","G179362-","G179363-","-196615A"],"OPG199":["E6K"]},"labels":{"aa":"OPG199: E6K"}}},{"name":"ON595760","node_attrs":{"div":556,"accession":"ON595760","author":{"author":"Laubscher,F.,Chudzinski,V.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinski,V.,Schibler,M.,Kaiser,L.,Renzoni,A."},"country":{"value":"Switzerland"},"institution":{"value":"Laboratory of Viorology, University Hospital of Geneva, Switzerland"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV-CH-38134631/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-19"},"strain_display":{"value":"Switzerland/ON595760/2022-05-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","T133101-","T133102-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"]}}},{"name":"OP341487","node_attrs":{"div":560,"accession":"OP341487","author":{"author":"Welkers,M.,Jonges,M.,de Regt,M.,Ooijevaar,R.,Wagemakers,A.","value":"Welkers,M.,Jonges,M.,de Regt,M.,Ooijevaar,R.,Wagemakers,A."},"country":{"value":"Netherlands"},"institution":{"value":"Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Netherlands/NH-AUMC-0060/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-05"},"strain_display":{"value":"Netherlands/OP341487/2022-08-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C96773T","C109432T","C114985T","C142356T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG117":["S242L"],"OPG129":["D525N"],"OPG133":["D238N"],"OPG163":["S52F"]},"labels":{"aa":"OPG117: S242L; OPG129: D525N; OPG133: D238N; OPG163: S52F"}}},{"name":"OP324507","node_attrs":{"div":558,"accession":"OP324507","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0194/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-27"},"strain_display":{"value":"Portugal/OP324507/2022-06-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","C142461T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G151793C","-196615A"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG163":["S87L"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG163: S87L"}}},{"name":"OP310062","node_attrs":{"div":556,"accession":"OP310062","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MpxV/human/USA/WA-UW-089836/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP310062/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP245340","node_attrs":{"div":557,"accession":"OP245340","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPX/PT0090/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-21"},"strain_display":{"value":"Portugal/OP245340/2022-07-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C774-","G775-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159001A","-179175T","T179244-","C179245-","G179246-","T179247-","A196659-","T196660-"],"OPG185":["D29N"]},"labels":{"aa":"OPG185: D29N"}}},{"name":"OP205093","node_attrs":{"div":556,"accession":"OP205093","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_UK_2022_9000105"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-14"},"strain_display":{"value":"United Kingdom/OP205093/2022-06-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP422342","node_attrs":{"div":559,"accession":"OP422342","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"country":{"value":"Austria"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV/Austria/MUW1539124/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-02"},"strain_display":{"value":"Austria/OP422342/2022-08-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G28490A","G102694A","C110960T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG044":["D134N"]},"labels":{"aa":"OPG044: D134N"}}},{"name":"OP382478","node_attrs":{"div":557,"accession":"OP382478","author":{"author":"Colson,P.","value":"Colson,P."},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV-IHU00001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-13"},"strain_display":{"value":"France/OP382478/2022-06-13"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C178006T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG205":["S784F"]},"labels":{"aa":"OPG205: S784F"}}},{"name":"OP382487","node_attrs":{"div":556,"accession":"OP382487","author":{"author":"Colson,P.","value":"Colson,P."},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV-IHU00010"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-18"},"strain_display":{"value":"France/OP382487/2022-07-18"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OP555554","node_attrs":{"div":559,"accession":"OP555554","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0475/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-08"},"strain_display":{"value":"Portugal/OP555554/2022-08-08"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G22039A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G170776A","C179853T"],"OPG037":["S132L"],"OPG198":["E247K"]},"labels":{"aa":"OPG037: S132L; OPG198: E247K"}}},{"name":"OP555484","node_attrs":{"div":561,"accession":"OP555484","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0388/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-12"},"strain_display":{"value":"Portugal/OP555484/2022-07-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G2174A","G25030A","G40324A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G167802A","G168044A","C195036T"],"OPG002":["S193L"],"OPG002_dup":["S193L"],"OPG040":["S150F"],"OPG193":["E157K"]},"labels":{"aa":"OPG002: S193L; OPG002_dup: S193L; OPG040: S150F; OPG193: E157K"}}},{"name":"OP536802","node_attrs":{"div":558,"accession":"OP536802","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"9000430"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536802/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","C87702T","G150484A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG176":["D226N"]},"labels":{"aa":"OPG176: D226N"}}},{"name":"OP615276","node_attrs":{"div":560,"accession":"OP615276","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00203/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-19"},"strain_display":{"value":"USA/OP615276/2022-07-19"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G59905A","G131350A","C135330T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G150732A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG080":["S705F"]},"labels":{"aa":"OPG080: S705F"}}},{"name":"OP605565","node_attrs":{"div":556,"accession":"OP605565","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Slovenia-MPXV-23-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Slovenia/OP605565/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OP605582","node_attrs":{"div":566,"accession":"OP605582","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Slovenia-MPXV-41-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Slovenia/OP605582/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C198-","-607T","C27187T","G176523A","C176524T","T176532G","G176536C","A176544T","A176550T","A176551G","T176552C","A176559C","T179059G","T179072A","G179076T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG043":["D257N"],"OPG205":["A290Y","I297L","N299C"]},"labels":{"aa":"OPG043: D257N; OPG205: A290Y, I297L, N299C"}}},{"name":"OP594206","node_attrs":{"div":558,"accession":"OP594206","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/RKI442"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP594206/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C22880T","C52956T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A163211-","A163212-","C163213-","T163214-"],"OPG038":["E94K"],"OPG071":["E495K"]},"labels":{"aa":"OPG038: E94K; OPG071: E495K"}}},{"name":"OP555658","node_attrs":{"div":558,"accession":"OP555658","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0591/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-13"},"strain_display":{"value":"Portugal/OP555658/2022-09-13"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","C136572T","C138333T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G158190A"],"OPG153":["E366K","D385-"]},"labels":{"aa":"OPG153: E366K, D385-"}}},{"name":"OP837473","node_attrs":{"div":562,"accession":"OP837473","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"VAC_INS_MPX_1054_L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-25"},"strain_display":{"value":"Colombia/OP837473/2022-10-25"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C33082T","C36405T","C40849T","G68103A","G117233A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C180361T","A197043-","T197044-","G197045-"],"OPG049":["D24N"],"OPG055":["A227T"],"OPG060":["E112K"]},"labels":{"aa":"OPG049: D24N; OPG055: A227T; OPG060: E112K"}}},{"name":"OP693649","node_attrs":{"div":558,"accession":"OP693649","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"ANT_INS_MPX_0039_L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-29"},"strain_display":{"value":"Colombia/OP693649/2022-07-29"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["A2840-","T2841-","C2842-","G127058A","G136194A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","T196865-","A196866-","G196867-"],"OPG148":["R358K"],"OPG153":["H492Y"]},"labels":{"aa":"OPG148: R358K; OPG153: H492Y"}}},{"name":"OP689665","node_attrs":{"div":556,"accession":"OP689665","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI512"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"Germany/OP689665/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP920696","node_attrs":{"div":559,"accession":"OP920696","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00358/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-05"},"strain_display":{"value":"USA/OP920696/2022-11-05"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G15683A","C104028T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G184416A"],"OPG123":["G348E"],"OPG210":["D1021N"]},"labels":{"aa":"OPG123: G348E; OPG210: D1021N"}}},{"name":"OQ411312","node_attrs":{"div":557,"accession":"OQ411312","author":{"author":"Laubscher,F.,Chudzinsk,V.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinsk,V.,Schibler,M.,Kaiser,L.,Renzoni,A."},"country":{"value":"Switzerland"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV-CH-38292866/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-08"},"strain_display":{"value":"Switzerland/OQ411312/2022-06-08"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C87764T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG109":["E562K"]},"labels":{"aa":"OPG109: E562K"}}},{"name":"OQ547754","node_attrs":{"div":556,"accession":"OQ547754","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI727"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ547754/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OR035730","node_attrs":{"div":560,"accession":"OR035730","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_124"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-20"},"strain_display":{"value":"Belgium/OR035730/2022-09-20"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C12298T","C32853T","G35385A","C169036T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG049":["G100E"]},"labels":{"aa":"OPG049: G100E"}}},{"name":"OR035720","node_attrs":{"div":557,"accession":"OR035720","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_114"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035720/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C8597T","T133101-","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ918699","node_attrs":{"div":561,"accession":"OQ918699","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00488/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-20"},"strain_display":{"value":"USA/OQ918699/2023-02-20"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G66587A","G106113A","G143857A","C144237T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C189810T"],"OPG165":["S241L"]},"labels":{"aa":"OPG165: S241L"}}},{"name":"OQ918696","node_attrs":{"div":562,"accession":"OQ918696","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00485/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-11"},"strain_display":{"value":"USA/OQ918696/2023-03-11"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G30285A","G37487A","C71193T","G119839A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C161690T","C177865T","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T179244-"],"OPG047":["P304S"],"OPG137":["E80K"],"OPG188":["S32F"],"OPG205":["S737F"]},"labels":{"aa":"OPG047: P304S; OPG137: E80K; OPG188: S32F; OPG205: S737F"}}},{"name":"OQ581848","node_attrs":{"div":557,"accession":"OQ581848","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"country":{"value":"Spain"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0006b/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-01"},"strain_display":{"value":"Spain/OQ581848/2022-07-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C133168-","T133169-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C174264T","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ570420","node_attrs":{"div":559,"accession":"OQ570420","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"country":{"value":"Italy"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"INMI-14732022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-11"},"strain_display":{"value":"Italy/OQ570420/2022-08-11"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C45203T","C88917T","C130606T","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OR449698","node_attrs":{"div":557,"accession":"OR449698","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI984"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449698/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C99954T","G150551-","A150563-","T150564-","G150565-","A150566-","T150567-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"OR264408","node_attrs":{"div":557,"accession":"OR264408","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"39_K"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-19"},"strain_display":{"value":"Australia/OR264408/2022-05-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["-607T","C21128T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-196615A"],"OPG037":["E436K"]},"labels":{"aa":"OPG037: E436K"}}},{"name":"OR264387","node_attrs":{"div":556,"accession":"OR264387","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"28_A"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-23"},"strain_display":{"value":"Australia/OR264387/2022-06-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264382","node_attrs":{"div":558,"accession":"OR264382","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"26_C"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-19"},"strain_display":{"value":"Australia/OR264382/2022-07-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["C118421T","G133806A","-179223A","-179224T","-179225A"],"OPG136":["M389I"]},"labels":{"aa":"OPG136: M389I"}}},{"name":"OX291424","node_attrs":{"div":557,"accession":"OX291424","country":{"value":"Slovakia"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"RNA"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-25"},"strain_display":{"value":"Slovakia/OX291424/2022-07-25"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","G57076A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG074":["S17L"]},"labels":{"aa":"OPG074: S17L"}}},{"name":"OX291694","node_attrs":{"div":561,"accession":"OX291694","country":{"value":"Slovakia"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"RNA"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Slovakia/OX291694/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","C15311T","C28887T","C54262T","G81015T","G141131A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG045":["E126K"],"OPG104":["T2K"]},"labels":{"aa":"OPG045: E126K; OPG104: T2K"}}},{"name":"OR759158","node_attrs":{"div":560,"accession":"OR759158","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Canada/ON-PHOL067/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759158/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G4454A","G6619A","G24622A","G70190A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C190323T","C192756T"],"OPG003":["H52Y"],"OPG003_dup":["H52Y"],"OPG040":["S286L"],"OPG089":["E109K"]},"labels":{"aa":"OPG003: H52Y; OPG003_dup: H52Y; OPG040: S286L; OPG089: E109K"}}},{"name":"OR035664","node_attrs":{"div":556,"accession":"OR035664","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_58"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-13"},"strain_display":{"value":"Belgium/OR035664/2022-06-13"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP415195","node_attrs":{"div":556,"accession":"OP415195","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPX_96X1Vd_9000217"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-03-XX"},"strain_display":{"value":"United Kingdom/OP415195/2022-03-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON649879","node_attrs":{"div":556,"accession":"ON649879","author":{"author":"Israeli,O.,Guedj-Dana,Y.,Lazar,S.,Shifman,O.,Erez,N.,Weiss,S.,Paran,N.,Israely,T.,Schuster,O.,Zvi,A.,Beth-Din,A.,Cohen Gihon,I.","value":"Israeli,O.,Guedj-Dana,Y.,Lazar,S.,Shifman,O.,Erez,N.,Weiss,S.,Paran,N.,Israely,T.,Schuster,O.,Zvi,A.,Beth-Din,A.,Cohen Gihon,I."},"country":{"value":"Israel"},"institution":{"value":"Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_ISR001_2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-20"},"strain_display":{"value":"Israel/ON649879/2022-05-20"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"ON631241","node_attrs":{"div":556,"accession":"ON631241","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"2022/2 SLO"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-24"},"strain_display":{"value":"Slovenia/ON631241/2022-05-24"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON563414","node_attrs":{"div":556,"accession":"ON563414","author":{"author":"Gigante,C.M.,Smole,S.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Brown,C.,Li,Y.","value":"Gigante,C.M.,Smole,S.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Brown,C.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_USA_2022_MA001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/ON563414/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON782022","node_attrs":{"div":556,"accession":"ON782022","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.,Sironen,T.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.,Sironen,T."},"country":{"value":"Finland"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPX-42/Finland/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-31"},"strain_display":{"value":"Finland/ON782022/2022-05-31"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"NODE_0000092","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","T4775-","A4776-","A4777-","T4779-","A4780-","A4781-","T4783-","T4784-","A4785-","T4786-","A4788-","T4790-","T4791-","A4792-","A4793-","T4795-","A4796-","A4797-","T4799-","T4800-","A4801-","T4802-","A4804-","T4806-","C77462T","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A192499-","A192500-","T192502-","A192504-","T192505-","A192506-","A192507-","T192509-","T192510-","A192511-","T192513-","T192514-","A192515-","A192516-","T192518-","A192520-","T192521-","A192522-","A192523-","T192525-","T192526-","A192527-","T192529-","T192530-","A196614-"],"OPG098":["S188F"]},"labels":{"aa":"OPG098: S188F"}},"children":[{"name":"OP378707","node_attrs":{"div":557,"accession":"OP378707","author":{"author":"Gigante,C.M.,Griffin-Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Crain,J.,Li,Y.","value":"Gigante,C.M.,Griffin-Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Crain,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_USA_2022_VA0004"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP378707/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C4778-","C4782-","G4787-","C4789-","C4794-","C4798-","G4803-","C4805-","C179154-","C179163-","G192501-","C192503-","G192508-","G192512-","G192517-","C192519-","G192524-","G192528-"]}}},{"name":"OR759183","node_attrs":{"div":560,"accession":"OR759183","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Canada/ON-PHOL095/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759183/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-606T","-4775T","-4776A","-4777A","-4779T","-4780A","-4781A","-4783T","-4784T","-4785A","-4786T","-4788A","-4790T","-4791T","-4792A","-4793A","-4795T","-4796A","-4797A","-4799T","-4800T","-4801A","-4802T","-4804A","-4806T","C111164T","A143676G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C152385T","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-192499A","-192500A","-192502T","-192504A","-192505T","-192506A","-192507A","-192509T","-192510T","-192511A","-192513T","-192514T","-192515A","-192516A","-192518T","-192520A","-192521T","-192522A","-192523A","-192525T","-192526T","-192527A","-192529T","-192530T","-196614A"],"OPG130":["E247K"],"OPG165":["N54S"]},"labels":{"aa":"OPG130: E247K; OPG165: N54S"}}}]},{"name":"NODE_0000093","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C34432T","G190695A"],"OPG016":["E96K"],"OPG053":["E87K"]},"labels":{"aa":"OPG016: E96K; OPG053: E87K"}},"children":[{"name":"OP642382","node_attrs":{"div":560,"accession":"OP642382","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"ANT-LDSP-ANT-MPX-24812-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-09"},"strain_display":{"value":"Colombia/OP642382/2022-09-09"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C67439T","G154993A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG085":["D365N"]},"labels":{"aa":"OPG085: D365N"}}},{"name":"OR126131","node_attrs":{"div":561,"accession":"OR126131","author":{"author":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C.","value":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C."},"country":{"value":"Spain"},"institution":{"value":"Hospital Ramon y Cajal, Microbiology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"HRYC_MPXV001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-21"},"strain_display":{"value":"Spain/OR126131/2022-09-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C11749-","C48324T","G101294A","C141757T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG120":["S152L"]},"labels":{"aa":"OPG120: S152L"}}}]},{"name":"NODE_0000094","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G98456A","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-179189A","T179244-","T179247-","T179248-","A179249-","T179250-","T179251-","T179253-","T179254-","T179255-","T179258-","T179260-","A179261-"],"OPG118":["G4E"]},"labels":{"aa":"OPG118: G4E"}},"children":[{"name":"OP894033","node_attrs":{"div":557,"accession":"OP894033","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI613"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP894033/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C179245-","G179246-","G179252-","G179256-","G179257-","C179259-","G181052-"],"OPG209":["G179-"]},"labels":{"aa":"OPG209: G179-"}}},{"name":"OR086985","node_attrs":{"div":560,"accession":"OR086985","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_176/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR086985/2022-07-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G18442A","C101656T","-133096T","-133097T","-133098T","-133099T","-133100T","-133101T","G170981A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-179244T","-179247T","-179248T","-179249A","-179250T","-179251T","-179253T","-179254T","-179255T","-179258T","-179260T","-179261A","A196780-","A196781-","T196782-"]}}}]},{"name":"NODE_0000095","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G53326A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}},"children":[{"name":"OQ320508","node_attrs":{"div":561,"accession":"OQ320508","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Burroughs,M.R.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Burroughs,M.R.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_USA_2022_TX0032"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ320508/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C102640T","C124036T","C136033T","C142626T","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG163":["S142L"]},"labels":{"aa":"OPG163: S142L"}}},{"name":"OR264430","node_attrs":{"div":559,"accession":"OR264430","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"51_B"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-05"},"strain_display":{"value":"Australia/OR264430/2022-09-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["C15582T","C121104T"],"OPG138":["R10K"]},"labels":{"aa":"OPG138: R10K"}}}]},{"name":"NODE_0000096","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G43620A"]}},"children":[{"name":"OQ672580","node_attrs":{"div":565,"accession":"OQ672580","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"country":{"value":"Taiwan"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/human/Taiwan/110-093354/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-XX"},"strain_display":{"value":"Taiwan/OQ672580/2023-03-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["T4795C","C39503G","A44076G","G45563A","T69121C","T80764C","A130204G","A143123G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG057":["K231N"],"OPG064":["F608S"],"OPG087":["Y89H"],"OPG104":["N86D"],"OPG164":["T116A"]},"labels":{"aa":"OPG057: K231N; OPG064: F608S; OPG087: Y89H; OPG104: N86D; OPG164: T116A"}}},{"name":"OR759224","node_attrs":{"div":558,"accession":"OR759224","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Canada/ON-PHOL137/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-01"},"strain_display":{"value":"Canada/OR759224/2022-07-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C1554T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G195656A"],"OPG001":["A8T"],"OPG001_dup":["A8T"]},"labels":{"aa":"OPG001: A8T; OPG001_dup: A8T"}}}]},{"name":"NODE_0000097","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C101074T","G138682A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A"],"OPG156":["S243F"]},"labels":{"aa":"OPG156: S243F"}},"children":[{"name":"OR086993","node_attrs":{"div":559,"accession":"OR086993","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_184/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-03"},"strain_display":{"value":"Belgium/OR086993/2022-08-03"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G178410A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR463732","node_attrs":{"div":559,"accession":"OR463732","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI767"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OR463732/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G120394A","G150551-","G150568-","A150569-","T150570-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","A181253-"],"OPG137":["E265K"]},"labels":{"aa":"OPG137: E265K"}}}]},{"name":"NODE_0000098","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C34784T","C101418T","G109844A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG054":["D405N"],"OPG120":["D111N"]},"labels":{"aa":"OPG054: D405N; OPG120: D111N"}},"children":[{"name":"OR743498","node_attrs":{"div":562,"accession":"OR743498","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1029"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-10-XX"},"strain_display":{"value":"Germany/OR743498/2023-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C45528T","C84767T","C170791T"],"OPG064":["R124K"]},"labels":{"aa":"OPG064: R124K"}}},{"name":"OR743494","node_attrs":{"div":559,"accession":"OR743494","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1025"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-09-XX"},"strain_display":{"value":"Germany/OR743494/2023-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G179263-","C179264-"]}}}]},{"name":"NODE_0000099","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C67289T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG085":["E415K"]},"labels":{"aa":"OPG085: E415K"}},"children":[{"name":"OR500079","node_attrs":{"div":562,"accession":"OR500079","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"country":{"value":"Romania"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Romania/B-16/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-04"},"strain_display":{"value":"Romania/OR500079/2022-08-04"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A31817T","G74360A","G97717T","C133109A","C166374G","T166375G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG094":["R194H"],"OPG117":["E557*"],"OPG191":["L72G"]},"labels":{"aa":"OPG094: R194H; OPG117: E557*; OPG191: L72G"}}},{"name":"NODE_0000100","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C23567T","G67527A","G77052A"]}},"children":[{"name":"OP415212","node_attrs":{"div":560,"accession":"OP415212","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPX_UbfBKN_9000238"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415212/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OP536788","node_attrs":{"div":560,"accession":"OP536788","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"9000413"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP536788/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A"]}}}]}]},{"name":"NODE_0000101","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G47746-","G49680-","G49710-","G62109-","A62110-","T62111-","A62112-","A62113-","A62114-","G62115-","A62116-","G62117-","T62118-","C62119-","C62120-","T62121-","A62122-","T62123-","A62124-","T62125-","A62126-","T62127-","T62128-","T62129-","G62130-","A62131-","A62132-","A62133-","A62134-","T62135-","C62136-","G62137-","T62138-","T62139-","A62140-","C62141-","G62142-","G62143-","T62144-","T62145-","C62146-","G62147-","A62148-","T62149-","T62150-","A62151-","C62166-","A62167-","T62168-","T62169-","G62170-","T62171-","G62172-","A62173-","A62174-","T62175-","A62176-","T62177-","A62178-","T62179-","C62180-","A62181-","T62182-","T62183-","A62184-","G62185-","G62186-","A62187-","T62188-","T62189-","T62190-","A62191-","A62192-","C62193-","T62194-","C62195-","C62196-","T62197-","T62198-","G62199-","A62200-","C62201-","T62202-","A62203-","T62204-","C62205-","A62206-","T62207-","G62208-","G62209-","C62210-","G62211-","G62212-","T62213-","G62214-","C62215-","C62216-","A62217-","G62218-","A62219-","A62220-","A62221-","T62222-","T62223-","A62224-","C62225-","C62226-","A62227-","T62228-","C62229-","A62230-","A62231-","A62232-","A62233-","G62234-","C62235-","A62236-","T62237-","T62238-","A62239-","A62240-","T62241-","A62242-","C62243-","A62244-","G62245-","T62246-","T62247-","A62248-","T62249-","G62250-","C62251-","A62252-","G62253-","A62254-","T62255-","C62256-","G62257-","C62258-","A62259-","G62260-","T62261-","T62262-","A62263-","G62264-","A62265-","A62266-","C62267-","G62268-","G62269-","T62270-","T62271-","A62272-","T62273-","A62274-","G62275-","C62276-","A62277-","T62278-","C62279-","C62280-","A62281-","C62282-","C62283-","A62284-","T62285-","T62286-","T62287-","A62288-","T62289-","A62290-","T62291-","C62292-","T62293-","A62294-","A62295-","A62296-","A62297-","A62298-","T62299-","T62300-","A62301-","G62302-","A62303-","T62304-","C62305-","A62306-","A62307-","A62308-","G62309-","A62310-","A62311-","T62312-","A62313-","T62314-","G62315-","T62316-","G62317-","A62318-","C62319-","A62320-","A62321-","C62322-","G62323-","T62324-","C62325-","C62326-","T62327-","A62328-","G62329-","T62330-","T62331-","G62332-","T62333-","A62334-","T62335-","A62336-","C62337-","T62338-","G62339-","A62340-","G62341-","A62342-","A62343-","T62344-","T62345-","G62346-","A62347-","C62348-","G62349-","A62350-","A62351-","A62352-","C62353-","A62354-","A62355-","T62356-","G62357-","T62358-","T62359-","T62360-","C62361-","T62362-","T62363-","A62364-","C62365-","A62366-","T62367-","A62368-","T62369-","T62370-","T62371-","T62372-","T62373-","T62374-","T62375-","C62376-","T62377-","T62378-","A62379-","T62380-","T62381-","A62382-","G62383-","T62384-","A62385-","A62386-","C62387-","C62388-","G62389-","A62390-","C62391-","T62392-","T62393-","A62394-","A62395-","T62396-","A62397-","G62398-","T62399-","A62400-","G62401-","G62402-","A62403-","A62404-","C62405-","T62406-","G62407-","G62408-","A62409-","A62410-","A62411-","A62412-","C62413-","T62414-","A62415-","G62416-","A62417-","C62418-","T62419-","T62420-","G62421-","A62422-","T62423-","T62424-","A62425-","T62426-","T62427-","C62428-","T62429-","A62430-","T62431-","A62432-","A62433-","G62434-","T62435-","A62436-","T62437-","A62438-","G62439-","A62440-","T62441-","A62442-","C62443-","C62444-","C62445-","T62446-","T62447-","C62448-","C62449-","A62450-","A62451-","A62452-","T62453-","A62454-","A62455-","T62456-","G62457-","T62458-","T62459-","C62460-","T62461-","C62462-","T62463-","T62464-","T62465-","G62466-","A62467-","T62468-","A62469-","A62470-","A62471-","A62472-","G62473-","T62474-","T62475-","C62476-","C62477-","A62478-","G62479-","A62480-","A62481-","A62482-","A62483-","T62484-","G62485-","T62486-","A62487-","G62488-","A62489-","A62490-","T62491-","T62492-","T62493-","T62494-","T62495-","T62496-","A62497-","A62498-","A62499-","A62500-","A62501-","G62502-","T62503-","T62504-","A62505-","T62506-","C62507-","T62508-","T62509-","T62510-","T62511-","G62512-","C62513-","T62514-","A62515-","T62516-","T62517-","A62518-","C62519-","T62520-","A62521-","A62522-","T62523-","A62524-","T62525-","C62526-","G62527-","T62528-","G62529-","G62530-","T62531-","T62532-","A62533-","G62534-","A62535-","C62536-","G62537-","C62538-","T62539-","T62540-","A62541-","T62542-","T62543-","A62544-","T62545-","T62546-","A62547-","A62548-","T62549-","A62550-","T62551-","G62552-","A62553-","G62554-","T62555-","G62556-","A62557-","T62558-","G62559-","A62560-","A62561-","A62562-","T62563-","C62564-","C62565-","A62566-","C62567-","A62568-","C62569-","C62570-","G62571-","C62572-","T62573-","T62574-","C62575-","T62576-","A62577-","G62578-","A62579-","T62580-","A62581-","T62582-","C62583-","G62584-","C62585-","T62586-","T62587-","T62588-","T62589-","A62590-","T62591-","T62592-","T62593-","C62594-","C62595-","A62596-","C62597-","A62598-","T62599-","T62600-","A62601-","G62602-","A62603-","T62604-","G62605-","G62606-","T62607-","A62608-","A62609-","A62610-","T62611-","C62612-","C62613-","A62614-","A62615-","T62616-","A62617-","G62618-","T62619-","G62620-","A62621-","A62622-","A62623-","C62624-","T62625-","A62626-","T62627-","C62628-","T62629-","T62630-","A62703-","T62704-","A62705-","A62706-","A62707-","C62708-","A62709-","A62710-","T62711-","T62712-","T62713-","C62714-","A62715-","C62716-","A62717-","A62718-","A62719-","T62720-","G62721-","G62722-","A62723-","T62724-","G62725-","T62726-","T62727-","A62728-","A62729-","T62730-","G62731-","T62732-","A62733-","T62734-","T62735-","A62736-","G62737-","T62738-","A62739-","G62740-","G62741-","A62742-","A62743-","A62744-","T62745-","T62746-","T62747-","T62748-","T62749-","T62750-","G62751-","A62752-","C62753-","G62754-","C62755-","T62756-","A62757-","G62758-","T62759-","G62760-","G62761-","A62762-","A62763-","T62764-","T62765-","G62766-","A62767-","A62768-","G62769-","A62770-","T62771-","T62772-","C62773-","T62774-","A62775-","A62776-","T62777-","G62778-","G62779-","A62780-","T62781-","G62782-","A62783-","T62784-","G62785-","T62786-","T62787-","C62788-","T62789-","A62790-","C62791-","C62792-","T62793-","A62794-","T62795-","T62796-","T62797-","C62798-","A62799-","T62800-","C62801-","C62802-","G62803-","A62804-","T62805-","A62806-","A62807-","C62808-","A62809-","T62810-","G62811-","T62812-","T62813-","A62814-","A62815-","T62816-","T62817-","T62818-","C62819-","C62820-","A62821-","A62822-","T62823-","A62824-","C62825-","C62826-","A62827-","A62828-","C62829-","G62830-","G62831-","T62832-","T62833-","T62834-","T62835-","A62836-","A62837-","T62838-","A62839-","T62840-","T62841-","T62842-","C62843-","G62844-","A62845-","T62846-","G62847-","A62848-","T62849-","A62850-","T62851-","A62852-","C62853-","G62854-","G62855-","T62856-","A62857-","G62858-","T62859-","C62860-","T62861-","C62862-","T62863-","C62864-","T62865-","T62866-","T62867-","C62868-","G62869-","G62870-","A62871-","C62872-","T62873-","T62874-","A62875-","T62876-","A62877-","T62878-","A62879-","G62880-","C62881-","T62882-","T62883-","A62884-","T62885-","T62886-","C62887-","C62888-","A62889-","C62890-","A62891-","A62892-","T62893-","A62894-","C62895-","G62896-","A62897-","G62898-","T62899-","C62900-","A62901-","T62902-","T62903-","A62904-","T62905-","A62906-","T62907-","A62908-","C62909-","T62910-","C62911-","C62912-","A62913-","A62914-","A62915-","A62916-","A62917-","A62918-","C62919-","A62920-","A62921-","A62922-","A62923-","T62924-","A62925-","A62926-","C62927-","T62928-","A62929-","G62930-","T62931-","A62932-","T62933-","A62934-","A62935-","A62936-","A62937-","T62938-","C62939-","T62940-","G62941-","T62942-","A62943-","T62944-","C62945-","G62946-","A62947-","A62948-","T62949-","G62950-","G62951-","G62952-","A62953-","A62954-","A62955-","A62956-","A62957-","C62958-","G62959-","A62960-","A62961-","A62962-","T62963-","T62964-","A62965-","T62966-","C62967-","G62968-","A62969-","T62970-","A62971-","T62972-","A62973-","G62974-","G62975-","T62976-","A62977-","T62978-","A62979-","G62980-","A62981-","A62982-","T62983-","C62984-","C62985-","G62986-","G62987-","A62988-","A62989-","C62990-","A62991-","T62992-","T62993-","G62994-","A62995-","A62996-","C62997-","G62998-","T62999-","A63000-","T63001-","T63002-","A63003-","A63004-","T63005-","A63006-","C63007-","T63008-","T63009-","A63010-","A63011-","T63012-","T63013-","C63014-","T63015-","T63016-","T63017-","T63018-","T63019-","C63020-","A63021-","G63022-","T63023-","G63024-","G63025-","T63026-","A63027-","A63028-","G63029-","A63030-","A63031-","C63032-","C63033-","G63034-","A63035-","T63036-","A63037-","G63038-","G63039-","T63040-","T63041-","A63042-","T63043-","T63044-","G63045-","A63046-","C63047-","A63048-","T63049-","T63050-","G63051-","T63052-","A63053-","T63054-","G63055-","G63056-","T63057-","T63058-","T63059-","T63060-","A63061-","A63062-","A63063-","T63064-","A63065-","T63066-","T63067-","C63068-","T63069-","A63070-","T63071-","A63072-","A63073-","C63074-","T63075-","T63076-","G63077-","A63078-","G63079-","A63080-","C63081-","T63082-","T63083-","G63084-","A63085-","T63086-","A63087-","G63088-","A63089-","T63090-","A63091-","T63092-","T63093-","A63094-","A63095-","T63096-","G63097-","A63098-","C63099-","G63100-","A63101-","A63102-","T63103-","T63104-","G63105-","A63106-","A63107-","A63108-","A63109-","T63110-","T63111-","A63112-","T63113-","T63114-","T63115-","T63116-","T63117-","A63118-","T63119-","C63120-","A63121-","C63122-","C63123-","A63124-","C63125-","G63126-","T63127-","G63128-","T63129-","G63130-","T63131-","T63132-","T63133-","C63134-","A63135-","G63136-","G63137-","A63138-","T63139-","C63140-","A63141-","T63142-","C63143-","G63144-","T63145-","C63146-","G63147-","A63148-","C63149-","G63150-","C63151-","C63152-","A63153-","G63154-","T63155-","T63156-","A63157-","A63158-","C63159-","C63160-","A63161-","A63162-","C63163-","C63164-","G63165-","A63166-","A63167-","T63168-","G63169-","G63170-","A63171-","G63172-","T63173-","A63174-","A63175-","A63176-","A63177-","T63178-","A63179-","A63180-","A63181-","T63182-","A63183-","T63184-","C63185-","A63186-","T63187-","T63188-","A63189-","A63190-","T63191-","A63192-","T63193-","A63194-","T63195-","G63196-","C63197-","T63198-","C63199-","T63200-","A63201-","G63202-","A63203-","T63204-","A63205-","T63206-","T63207-","A63208-","G63209-","T63210-","A63211-","T63212-","T63213-","T63214-","T63215-","T63216-","A63217-","T63218-","T63219-","A63220-","A63221-","T63222-","C63223-","C63224-","T63225-","T63226-","T63227-","G63228-","A63229-","T63230-","T63231-","A63232-","T63233-","C63234-","A63235-","T63236-","C63237-","T63238-","T63239-","C63240-","T63241-","C63242-","G63243-","T63244-","A63245-","C63246-","G63247-","C63248-","G63249-","A63250-","A63251-","T63252-","G63253-","A63254-","T63255-","T63256-","C63257-","C63258-","A63259-","T63260-","G63261-","A63262-","T63263-","C63264-","A63265-","A63266-","G63267-","A63268-","G63269-","T63270-","G63271-","A63272-","T63273-","T63274-","T63275-","G63276-","A63277-","G63278-","A63279-","A63280-","C63281-","A63282-","T63283-","C63284-","C63285-","T63286-","C63287-","C63288-","G63289-","G63290-","A63291-","G63292-","T63293-","A63294-","T63295-","T63296-","A63297-","A63298-","T63299-","G63300-","G63301-","G63302-","T63303-","T63304-","T63305-","A63306-","G63307-","T63308-","A63309-","A63310-","A63311-","C63312-","A63313-","G63314-","T63315-","C63316-","C63317-","A63318-","T63319-","C63320-","G63321-","T63322-","T63323-","G63324-","C63325-","A63326-","A63327-","T63328-","A63329-","A63330-","T63331-","A63332-","A63333-","A63334-","A63335-","G63336-","T63337-","T63338-","G63339-","T63340-","C63341-","C63342-","A63343-","A63344-","G63345-","T63346-","T63347-","A63348-","A63349-","A63350-","G63351-","G63352-","A63353-","T63354-","A63355-","T63356-","T63357-","A63358-","T63359-","G63360-","C63361-","A63362-","T63363-","T63364-","C63365-","G63366-","T63367-","T63368-","T63369-","A63370-","A63371-","A63372-","G63373-","A63374-","T63375-","A63376-","T63377-","C63378-","A63379-","C63380-","C63381-","T63382-","C63383-","A63384-","T63385-","C63386-","T63387-","A63388-","A63389-","C63390-","G63391-","G63392-","A63393-","G63394-","A63395-","C63396-","A63397-","A63398-","T63399-","T63400-","T63401-","T63402-","T63403-","T63404-","G63405-","G63406-","T63407-","A63408-","G63409-","G63410-","T63411-","T63412-","T63413-","T63414-","A63415-","G63416-","A63417-","G63418-","A63419-","C63420-","T63421-","T63422-","T63423-","G63424-","A63425-","A63426-","G63427-","C63428-","T63429-","A63430-","C63431-","T63432-","T63433-","G63434-","T63435-","T63436-","T63437-","A63438-","A63439-","C63440-","A63441-","A63442-","A63443-","G63444-","T63445-","T63446-","A63447-","T63448-","T63449-","C63450-","A63451-","T63452-","C63453-","G63454-","T63455-","C63456-","G63457-","T63458-","C63459-","T63460-","A63461-","C63462-","T63463-","A63464-","T63465-","T63466-","C63467-","T63468-","A63469-","T63470-","T63471-","T63472-","A63473-","A63474-","T63475-","T63476-","T63477-","T63478-","G63479-","T63480-","A63481-","G63482-","T63483-","T63484-","A63485-","A63486-","T63487-","T63488-","T63489-","A63490-","T63491-","C63492-","A63493-","C63494-","A63495-","T63496-","A63497-","T63498-","C63499-","A63500-","C63501-","A63502-","T63503-","T63504-","C89166T","C112408T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG131":["L157F"]},"labels":{"aa":"OPG131: L157F"}},"children":[{"name":"OQ672570","node_attrs":{"div":558,"accession":"OQ672570","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"02112022_anal"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-02"},"strain_display":{"value":"Belgium/OQ672570/2022-11-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"OPG068":["D494-"],"OPG081":["N46-","R47-","T48-","V49-","T50-","I51-","F52-","K53-","Y54-","I55-","G56-","L57-","F58-","I59-"]},"labels":{"aa":"OPG068: D494-; OPG081: N46-, R47-, T48-, V49-, T50-, I51-, F52-, K53-, Y54-, I55-, G56-, L57-, F58-, I59-"}}},{"name":"NODE_0000102","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","G187391A","A194549-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-"],"OPG002":["R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-","C47-"],"OPG002_dup":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-"]},"labels":{"aa":"OPG002: R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-, C47-; OPG002_dup: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-"}},"children":[{"name":"OQ672572","node_attrs":{"div":559,"accession":"OQ672572","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"26012023_anal"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-26"},"strain_display":{"value":"Belgium/OQ672572/2023-01-26"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-47746G","-49680G","-49710G","-62109G","-62110A","-62111T","-62112A","-62113A","-62114A","-62115G","-62116A","-62117G","-62118T","-62119C","-62120C","-62121T","-62122A","-62123T","-62124A","-62125T","-62126A","-62127T","-62128T","-62129T","-62130G","-62131A","-62132A","-62133A","-62134A","-62135T","-62136C","-62137G","-62138T","-62139T","-62140A","-62141C","-62142G","-62143G","-62144T","-62145T","-62146C","-62147G","-62148A","-62149T","-62150T","-62151A","-62166C","-62167A","-62168T","-62169T","-62170G","-62171T","-62172G","-62173A","-62174A","-62175T","-62176A","-62177T","-62178A","-62179T","-62180C","-62181A","-62182T","-62183T","-62184A","-62185G","-62186G","-62187A","-62188T","-62189T","-62190T","-62191A","-62192A","-62193C","-62194T","-62195C","-62196C","-62197T","-62198T","-62199G","-62200A","-62201C","-62202T","-62203A","-62204T","-62205C","-62206A","-62207T","-62208G","-62209G","-62210C","-62211G","-62212G","-62213T","-62214G","-62215C","-62216C","-62217A","-62218G","-62219A","-62220A","-62221A","-62222T","-62223T","-62224A","-62225C","-62226C","-62227A","-62228T","-62229C","-62230A","-62231A","-62232A","-62233A","-62234G","-62235C","-62236A","-62237T","-62238T","-62239A","-62240A","-62241T","-62242A","-62243C","-62244A","-62245G","-62246T","-62247T","-62248A","-62249T","-62250G","-62251C","-62252A","-62253G","-62254A","-62255T","-62256C","-62257G","-62258C","-62259A","-62260G","-62261T","-62262T","-62263A","-62264G","-62265A","-62266A","-62267C","-62268G","-62269G","-62270T","-62271T","-62272A","-62273T","-62274A","-62275G","-62276C","-62277A","-62278T","-62279C","-62280C","-62281A","-62282C","-62283C","-62284A","-62285T","-62286T","-62287T","-62288A","-62289T","-62290A","-62291T","-62292C","-62293T","-62294A","-62295A","-62296A","-62297A","-62298A","-62299T","-62300T","-62301A","-62302G","-62303A","-62304T","-62305C","-62306A","-62307A","-62308A","-62309G","-62310A","-62311A","-62312T","-62313A","-62314T","-62315G","-62316T","-62317G","-62318A","-62319C","-62320A","-62321A","-62322C","-62323G","-62324T","-62325C","-62326C","-62327T","-62328A","-62329G","-62330T","-62331T","-62332G","-62333T","-62334A","-62335T","-62336A","-62337C","-62338T","-62339G","-62340A","-62341G","-62342A","-62343A","-62344T","-62345T","-62346G","-62347A","-62348C","-62349G","-62350A","-62351A","-62352A","-62353C","-62354A","-62355A","-62356T","-62357G","-62358T","-62359T","-62360T","-62361C","-62362T","-62363T","-62364A","-62365C","-62366A","-62367T","-62368A","-62369T","-62370T","-62371T","-62372T","-62373T","-62374T","-62375T","-62376C","-62377T","-62378T","-62379A","-62380T","-62381T","-62382A","-62383G","-62384T","-62385A","-62386A","-62387C","-62388C","-62389G","-62390A","-62391C","-62392T","-62393T","-62394A","-62395A","-62396T","-62397A","-62398G","-62399T","-62400A","-62401G","-62402G","-62403A","-62404A","-62405C","-62406T","-62407G","-62408G","-62409A","-62410A","-62411A","-62412A","-62413C","-62414T","-62415A","-62416G","-62417A","-62418C","-62419T","-62420T","-62421G","-62422A","-62423T","-62424T","-62425A","-62426T","-62427T","-62428C","-62429T","-62430A","-62431T","-62432A","-62433A","-62434G","-62435T","-62436A","-62437T","-62438A","-62439G","-62440A","-62441T","-62442A","-62443C","-62444C","-62445C","-62446T","-62447T","-62448C","-62449C","-62450A","-62451A","-62452A","-62453T","-62454A","-62455A","-62456T","-62457G","-62458T","-62459T","-62460C","-62461T","-62462C","-62463T","-62464T","-62465T","-62466G","-62467A","-62468T","-62469A","-62470A","-62471A","-62472A","-62473G","-62474T","-62475T","-62476C","-62477C","-62478A","-62479G","-62480A","-62481A","-62482A","-62483A","-62484T","-62485G","-62486T","-62487A","-62488G","-62489A","-62490A","-62491T","-62492T","-62493T","-62494T","-62495T","-62496T","-62497A","-62498A","-62499A","-62500A","-62501A","-62502G","-62503T","-62504T","-62505A","-62506T","-62507C","-62508T","-62509T","-62510T","-62511T","-62512G","-62513C","-62514T","-62515A","-62516T","-62517T","-62518A","-62519C","-62520T","-62521A","-62522A","-62523T","-62524A","-62525T","-62526C","-62527G","-62528T","-62529G","-62530G","-62531T","-62532T","-62533A","-62534G","-62535A","-62536C","-62537G","-62538C","-62539T","-62540T","-62541A","-62542T","-62543T","-62544A","-62545T","-62546T","-62547A","-62548A","-62549T","-62550A","-62551T","-62552G","-62553A","-62554G","-62555T","-62556G","-62557A","-62558T","-62559G","-62560A","-62561A","-62562A","-62563T","-62564C","-62565C","-62566A","-62567C","-62568A","-62569C","-62570C","-62571G","-62572C","-62573T","-62574T","-62575C","-62576T","-62577A","-62578G","-62579A","-62580T","-62581A","-62582T","-62583C","-62584G","-62585C","-62586T","-62587T","-62588T","-62589T","-62590A","-62591T","-62592T","-62593T","-62594C","-62595C","-62596A","-62597C","-62598A","-62599T","-62600T","-62601A","-62602G","-62603A","-62604T","-62605G","-62606G","-62607T","-62608A","-62609A","-62610A","-62611T","-62612C","-62613C","-62614A","-62615A","-62616T","-62617A","-62618G","-62619T","-62620G","-62621A","-62622A","-62623A","-62624C","-62625T","-62626A","-62627T","-62628C","-62629T","-62630T","-62703A","-62704T","-62705A","-62706A","-62707A","-62708C","-62709A","-62710A","-62711T","-62712T","-62713T","-62714C","-62715A","-62716C","-62717A","-62718A","-62719A","-62720T","-62721G","-62722G","-62723A","-62724T","-62725G","-62726T","-62727T","-62728A","-62729A","-62730T","-62731G","-62732T","-62733A","-62734T","-62735T","-62736A","-62737G","-62738T","-62739A","-62740G","-62741G","-62742A","-62743A","-62744A","-62745T","-62746T","-62747T","-62748T","-62749T","-62750T","-62751G","-62752A","-62753C","-62754G","-62755C","-62756T","-62757A","-62758G","-62759T","-62760G","-62761G","-62762A","-62763A","-62764T","-62765T","-62766G","-62767A","-62768A","-62769G","-62770A","-62771T","-62772T","-62773C","-62774T","-62775A","-62776A","-62777T","-62778G","-62779G","-62780A","-62781T","-62782G","-62783A","-62784T","-62785G","-62786T","-62787T","-62788C","-62789T","-62790A","-62791C","-62792C","-62793T","-62794A","-62795T","-62796T","-62797T","-62798C","-62799A","-62800T","-62801C","-62802C","-62803G","-62804A","-62805T","-62806A","-62807A","-62808C","-62809A","-62810T","-62811G","-62812T","-62813T","-62814A","-62815A","-62816T","-62817T","-62818T","-62819C","-62820C","-62821A","-62822A","-62823T","-62824A","-62825C","-62826C","-62827A","-62828A","-62829C","-62830G","-62831G","-62832T","-62833T","-62834T","-62835T","-62836A","-62837A","-62838T","-62839A","-62840T","-62841T","-62842T","-62843C","-62844G","-62845A","-62846T","-62847G","-62848A","-62849T","-62850A","-62851T","-62852A","-62853C","-62854G","-62855G","-62856T","-62857A","-62858G","-62859T","-62860C","-62861T","-62862C","-62863T","-62864C","-62865T","-62866T","-62867T","-62868C","-62869G","-62870G","-62871A","-62872C","-62873T","-62874T","-62875A","-62876T","-62877A","-62878T","-62879A","-62880G","-62881C","-62882T","-62883T","-62884A","-62885T","-62886T","-62887C","-62888C","-62889A","-62890C","-62891A","-62892A","-62893T","-62894A","-62895C","-62896G","-62897A","-62898G","-62899T","-62900C","-62901A","-62902T","-62903T","-62904A","-62905T","-62906A","-62907T","-62908A","-62909C","-62910T","-62911C","-62912C","-62913A","-62914A","-62915A","-62916A","-62917A","-62918A","-62919C","-62920A","-62921A","-62922A","-62923A","-62924T","-62925A","-62926A","-62927C","-62928T","-62929A","-62930G","-62931T","-62932A","-62933T","-62934A","-62935A","-62936A","-62937A","-62938T","-62939C","-62940T","-62941G","-62942T","-62943A","-62944T","-62945C","-62946G","-62947A","-62948A","-62949T","-62950G","-62951G","-62952G","-62953A","-62954A","-62955A","-62956A","-62957A","-62958C","-62959G","-62960A","-62961A","-62962A","-62963T","-62964T","-62965A","-62966T","-62967C","-62968G","-62969A","-62970T","-62971A","-62972T","-62973A","-62974G","-62975G","-62976T","-62977A","-62978T","-62979A","-62980G","-62981A","-62982A","-62983T","-62984C","-62985C","-62986G","-62987G","-62988A","-62989A","-62990C","-62991A","-62992T","-62993T","-62994G","-62995A","-62996A","-62997C","-62998G","-62999T","-63000A","-63001T","-63002T","-63003A","-63004A","-63005T","-63006A","-63007C","-63008T","-63009T","-63010A","-63011A","-63012T","-63013T","-63014C","-63015T","-63016T","-63017T","-63018T","-63019T","-63020C","-63021A","-63022G","-63023T","-63024G","-63025G","-63026T","-63027A","-63028A","-63029G","-63030A","-63031A","-63032C","-63033C","-63034G","-63035A","-63036T","-63037A","-63038G","-63039G","-63040T","-63041T","-63042A","-63043T","-63044T","-63045G","-63046A","-63047C","-63048A","-63049T","-63050T","-63051G","-63052T","-63053A","-63054T","-63055G","-63056G","-63057T","-63058T","-63059T","-63060T","-63061A","-63062A","-63063A","-63064T","-63065A","-63066T","-63067T","-63068C","-63069T","-63070A","-63071T","-63072A","-63073A","-63074C","-63075T","-63076T","-63077G","-63078A","-63079G","-63080A","-63081C","-63082T","-63083T","-63084G","-63085A","-63086T","-63087A","-63088G","-63089A","-63090T","-63091A","-63092T","-63093T","-63094A","-63095A","-63096T","-63097G","-63098A","-63099C","-63100G","-63101A","-63102A","-63103T","-63104T","-63105G","-63106A","-63107A","-63108A","-63109A","-63110T","-63111T","-63112A","-63113T","-63114T","-63115T","-63116T","-63117T","-63118A","-63119T","-63120C","-63121A","-63122C","-63123C","-63124A","-63125C","-63126G","-63127T","-63128G","-63129T","-63130G","-63131T","-63132T","-63133T","-63134C","-63135A","-63136G","-63137G","-63138A","-63139T","-63140C","-63141A","-63142T","-63143C","-63144G","-63145T","-63146C","-63147G","-63148A","-63149C","-63150G","-63151C","-63152C","-63153A","-63154G","-63155T","-63156T","-63157A","-63158A","-63159C","-63160C","-63161A","-63162A","-63163C","-63164C","-63165G","-63166A","-63167A","-63168T","-63169G","-63170G","-63171A","-63172G","-63173T","-63174A","-63175A","-63176A","-63177A","-63178T","-63179A","-63180A","-63181A","-63182T","-63183A","-63184T","-63185C","-63186A","-63187T","-63188T","-63189A","-63190A","-63191T","-63192A","-63193T","-63194A","-63195T","-63196G","-63197C","-63198T","-63199C","-63200T","-63201A","-63202G","-63203A","-63204T","-63205A","-63206T","-63207T","-63208A","-63209G","-63210T","-63211A","-63212T","-63213T","-63214T","-63215T","-63216T","-63217A","-63218T","-63219T","-63220A","-63221A","-63222T","-63223C","-63224C","-63225T","-63226T","-63227T","-63228G","-63229A","-63230T","-63231T","-63232A","-63233T","-63234C","-63235A","-63236T","-63237C","-63238T","-63239T","-63240C","-63241T","-63242C","-63243G","-63244T","-63245A","-63246C","-63247G","-63248C","-63249G","-63250A","-63251A","-63252T","-63253G","-63254A","-63255T","-63256T","-63257C","-63258C","-63259A","-63260T","-63261G","-63262A","-63263T","-63264C","-63265A","-63266A","-63267G","-63268A","-63269G","-63270T","-63271G","-63272A","-63273T","-63274T","-63275T","-63276G","-63277A","-63278G","-63279A","-63280A","-63281C","-63282A","-63283T","-63284C","-63285C","-63286T","-63287C","-63288C","-63289G","-63290G","-63291A","-63292G","-63293T","-63294A","-63295T","-63296T","-63297A","-63298A","-63299T","-63300G","-63301G","-63302G","-63303T","-63304T","-63305T","-63306A","-63307G","-63308T","-63309A","-63310A","-63311A","-63312C","-63313A","-63314G","-63315T","-63316C","-63317C","-63318A","-63319T","-63320C","-63321G","-63322T","-63323T","-63324G","-63325C","-63326A","-63327A","-63328T","-63329A","-63330A","-63331T","-63332A","-63333A","-63334A","-63335A","-63336G","-63337T","-63338T","-63339G","-63340T","-63341C","-63342C","-63343A","-63344A","-63345G","-63346T","-63347T","-63348A","-63349A","-63350A","-63351G","-63352G","-63353A","-63354T","-63355A","-63356T","-63357T","-63358A","-63359T","-63360G","-63361C","-63362A","-63363T","-63364T","-63365C","-63366G","-63367T","-63368T","-63369T","-63370A","-63371A","-63372A","-63373G","-63374A","-63375T","-63376A","-63377T","-63378C","-63379A","-63380C","-63381C","-63382T","-63383C","-63384A","-63385T","-63386C","-63387T","-63388A","-63389A","-63390C","-63391G","-63392G","-63393A","-63394G","-63395A","-63396C","-63397A","-63398A","-63399T","-63400T","-63401T","-63402T","-63403T","-63404T","-63405G","-63406G","-63407T","-63408A","-63409G","-63410G","-63411T","-63412T","-63413T","-63414T","-63415A","-63416G","-63417A","-63418G","-63419A","-63420C","-63421T","-63422T","-63423T","-63424G","-63425A","-63426A","-63427G","-63428C","-63429T","-63430A","-63431C","-63432T","-63433T","-63434G","-63435T","-63436T","-63437T","-63438A","-63439A","-63440C","-63441A","-63442A","-63443A","-63444G","-63445T","-63446T","-63447A","-63448T","-63449T","-63450C","-63451A","-63452T","-63453C","-63454G","-63455T","-63456C","-63457G","-63458T","-63459C","-63460T","-63461A","-63462C","-63463T","-63464A","-63465T","-63466T","-63467C","-63468T","-63469A","-63470T","-63471T","-63472T","-63473A","-63474A","-63475T","-63476T","-63477T","-63478T","-63479G","-63480T","-63481A","-63482G","-63483T","-63484T","-63485A","-63486A","-63487T","-63488T","-63489T","-63490A","-63491T","-63492C","-63493A","-63494C","-63495A","-63496T","-63497A","-63498T","-63499C","-63500A","-63501C","-63502A","-63503T","-63504T"]}}},{"name":"OQ672578","node_attrs":{"div":563,"accession":"OQ672578","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"23022023_anal"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-23"},"strain_display":{"value":"Belgium/OQ672578/2023-02-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A2611-","C2612-","A2613-","C2614-","G2615-","A2616-","T2617-","A2618-","G2619-","A2620-","C2621-","A2622-","T2653-","T2654-","T2655-","A2656-","C2657-","A2658-","C2659-","T2660-","T2661-","T2662-","C8201T","T39397C","C47694-","T47695-","C47696-","A47697-","T47698-","T47699-","A47700-","C47701-","G47702-","A47703-","G47704-","A47705-","C47706-","A47707-","T47708-","T47709-","G47710-","A47711-","A47712-","A47713-","C47714-","T47715-","A47716-","G47717-","G47718-","A47719-","T47720-","A47721-","T47722-","A47723-","T47724-","A47725-","A47726-","A47727-","A47728-","T47729-","T47730-","T47731-","A47732-","A47733-","G47734-","G47735-","G47736-","A47737-","A47738-","T47739-","G47740-","A47741-","T47742-","T47743-","A47744-","G47745-","A47747-","C47748-","T47749-","A47750-","C47751-","T47752-","A47753-","C47754-","T47755-","C47756-","T47757-","A47758-","G47759-","A47760-","A47761-","G47762-","A47763-","T47764-","A47765-","T47766-","A47767-","G47768-","C47769-","A47770-","C47771-","C47772-","A47773-","T47774-","C47775-","T47776-","A47777-","T47778-","T47779-","C47780-","C47781-","A47782-","A47783-","A47784-","T47785-","A47786-","A47787-","T47788-","C47789-","A47790-","G47791-","A47792-","A47793-","A47794-","A47795-","C47796-","T47797-","T47798-","A47799-","T47800-","A47801-","A47802-","A47803-","C47804-","T47805-","A47806-","T47807-","T47808-","C47809-","T47810-","C47811-","G47812-","G47813-","A47814-","C47815-","A47816-","T47817-","T47818-","T47819-","C47820-","A47821-","G47822-","T47823-","C47824-","A47825-","T47826-","T47827-","G47828-","G47829-","C47830-","A47831-","A47832-","A47833-","G47834-","C47835-","A47836-","T47837-","C47838-","A47839-","C47840-","A47841-","G47842-","A47843-","A47844-","T47845-","C47846-","C47847-","G47848-","A47849-","G47850-","T47851-","A47852-","A47853-","G47854-","A47855-","T47856-","G47857-","A47858-","T47859-","A47860-","T47861-","A47862-","T47863-","G47864-","C47865-","T47866-","C47867-","G47868-","C47869-","T47870-","G47871-","C47872-","T47873-","T47874-","T47875-","A47876-","C47877-","A47878-","T47879-","G47880-","T47881-","T47882-","T47883-","C47884-","C47885-","C47886-","A47887-","A47888-","T47889-","T47890-","T47891-","G47892-","T47893-","T47894-","T47895-","G47896-","G47897-","A47898-","G47899-","A47900-","T47901-","G47902-","A47903-","C47904-","C47905-","A47906-","T47907-","A47908-","G47909-","A47910-","T47911-","T47912-","C47913-","A47914-","T47915-","T47916-","T47917-","G47918-","T47919-","T47920-","A47921-","T47922-","A47923-","G47924-","A47925-","A47926-","T47927-","G47928-","C47929-","A47930-","T47931-","C47932-","C47933-","A47934-","A47935-","C47936-","A47937-","T47938-","T47939-","G47940-","T47941-","T47942-","C47943-","A47944-","T47945-","G47946-","A47947-","T47948-","A47949-","T47950-","A47951-","G47952-","T47953-","T47954-","G47955-","A47956-","A47957-","T47958-","C47959-","A47960-","T47961-","G47962-","T47963-","A47964-","T47965-","G47966-","C47967-","C47968-","T47969-","G47970-","T47971-","T47972-","C47973-","G47974-","T47975-","A47976-","T47977-","G47978-","C47979-","C47980-","T47981-","G47982-","T47983-","G47984-","G47985-","C47986-","T47987-","A47988-","A47989-","G47990-","A47991-","T47992-","A47993-","C47994-","T47995-","G47996-","T47997-","G47998-","T47999-","A48000-","A48001-","A48002-","G48003-","A48004-","A48005-","A48006-","T48007-","G48008-","G48009-","T48010-","A48011-","A48012-","A48013-","T48014-","A48015-","A48016-","A48017-","T48018-","A48019-","C48020-","T48021-","T48022-","T48023-","G48024-","A48025-","G48026-","A48027-","A48028-","T48029-","C48030-","T48031-","T48032-","T48033-","A48034-","A48035-","G48036-","A48037-","G48038-","T48039-","G48040-","C48041-","A48042-","T48043-","T48044-","G48045-","A48046-","C48047-","T48048-","T48049-","T48050-","G48051-","T48052-","T48053-","A48054-","G48055-","T48056-","G48057-","A48058-","A48059-","T48060-","A48061-","G48062-","G48063-","C48064-","A48065-","T48066-","T48067-","C48068-","C48069-","A48070-","T48071-","C48072-","T48073-","T48074-","T48075-","C48076-","T48077-","C48078-","C48079-","A48080-","A48081-","T48082-","A48083-","C48084-","T48085-","A48086-","A48087-","T48088-","T48089-","C48090-","A48091-","A48092-","A48093-","T48094-","T48095-","G48096-","T48097-","T48098-","A48099-","A48100-","A48101-","T48102-","T48103-","A48104-","A48105-","T48106-","A48107-","A48108-","T48109-","G48110-","G48111-","A48112-","A48113-","T48114-","A48115-","G48116-","T48117-","A48118-","T48119-","A48120-","A48121-","A48122-","T48123-","A48124-","G48125-","T48126-","T48127-","A48128-","T48129-","T48130-","A48131-","G48132-","T48133-","G48134-","A48135-","T48136-","A48137-","G48138-","G48139-","A48140-","T48141-","A48142-","G48143-","T48144-","A48145-","A48146-","A48147-","C48148-","A48149-","T48150-","A48151-","A48152-","T48153-","T48154-","A48155-","T48156-","T48157-","A48158-","G48159-","A48160-","A48161-","T48162-","A48163-","G48164-","T48165-","A48166-","G48167-","T48168-","G48169-","T48170-","A48171-","G48172-","T48173-","A48174-","T48175-","C48176-","A48177-","T48178-","A48179-","G48180-","A48181-","T48182-","A48183-","A48184-","C48185-","T48186-","C48187-","T48188-","C48189-","T48190-","T48191-","C48192-","T48193-","A48194-","T48195-","A48196-","A48197-","A48198-","A48199-","A48200-","A48201-","T48202-","G48203-","G48204-","A48205-","T48206-","T48207-","T48208-","T48209-","A48210-","T48211-","T48212-","C48213-","G48214-","T48215-","A48216-","G48217-","A48218-","A48219-","A48220-","G48221-","T48222-","A48223-","T48224-","C48225-","T48226-","T48227-","A48228-","T48229-","A48230-","T48231-","A48232-","C48233-","A48234-","C48235-","A48236-","G48237-","T48238-","A48239-","G48240-","A48241-","A48242-","A48243-","A48244-","T48245-","A48246-","A48247-","T48248-","A48249-","T48250-","A48251-","G48252-","A48253-","T48254-","T48255-","T48256-","T48257-","T48258-","T48259-","A48260-","A48261-","A48262-","G48263-","G48264-","A48265-","T48266-","G48267-","A48268-","T48269-","A48270-","C48271-","A48272-","T48273-","T48274-","A48275-","A48276-","G48277-","T48278-","A48279-","A48280-","A48281-","G48282-","T48283-","A48284-","A48285-","A48286-","C48287-","A48288-","A48289-","T48290-","T48291-","T48292-","T48293-","A48294-","C48295-","C48296-","C48297-","T48298-","C48299-","A48300-","A48301-","T48302-","C48303-","A48304-","T48305-","G48306-","T48307-","A48308-","C48309-","T48310-","A48311-","G48312-","C48313-","T48314-","C48315-","T48316-","C48317-","A48318-","A48319-","G48320-","T48321-","A48322-","T48323-","C48324-","T48325-","A48326-","G48327-","T48328-","T48329-","A48330-","G48331-","C48332-","A48333-","A48334-","T48335-","T48336-","T48337-","T48338-","C48339-","C48340-","T48341-","C48342-","A48343-","A48344-","C48345-","A48346-","T48347-","G48348-","T48349-","T48350-","A48351-","T48352-","T48353-","A48354-","C48355-","T48356-","A48357-","A48358-","G48359-","G48360-","A48361-","T48362-","G48363-","T48364-","A48365-","T48366-","T48367-","A48368-","G48369-","C48370-","T48371-","A48372-","A48373-","T48374-","A48375-","C48376-","C48377-","A48378-","A48379-","T48380-","T48381-","T48382-","T48383-","T48384-","T48385-","T48386-","G48387-","T48388-","T48389-","T48390-","T48391-","C48392-","A48393-","T48394-","A48395-","C48396-","A48397-","T48398-","A48399-","T48400-","G48401-","G48402-","T48403-","A48404-","C48405-","G48406-","A48407-","T48408-","G48409-","C48410-","T48411-","G48412-","T48413-","A48414-","A48415-","A48416-","G48417-","T48418-","A48419-","T48420-","A48421-","C48422-","G48423-","A48424-","A48425-","G48426-","C48427-","G48428-","G48429-","T48430-","T48431-","T48432-","T48433-","A48434-","C48435-","G48436-","A48437-","C48438-","A48439-","C48440-","G48441-","C48442-","A48443-","T48444-","T48445-","T48446-","G48447-","A48448-","T48449-","G48450-","C48451-","A48452-","C48453-","C48454-","C48455-","A48456-","C48457-","G48458-","T48459-","T48460-","G48461-","T48462-","A48463-","C48464-","G48465-","T48466-","T48467-","A48468-","A48469-","A48470-","G48471-","C48472-","A48473-","T48474-","T48475-","G48476-","A48477-","C48478-","T48479-","A48480-","A48481-","G48482-","A48483-","A48484-","T48485-","T48486-","A48487-","T48488-","T48489-","T48490-","A48491-","T48492-","C48493-","G48494-","T48495-","T48496-","T48497-","A48498-","G48499-","T48500-","A48501-","A48502-","C48503-","A48504-","C48505-","A48506-","A48507-","T48508-","A48509-","C48510-","A48511-","G48512-","T48513-","C48514-","G48515-","T48516-","A48517-","C48518-","A48519-","A48520-","G48521-","G48522-","A48523-","A48524-","A48525-","C48526-","A48527-","G48528-","T48529-","G48530-","C48531-","A48532-","T48533-","A48534-","A48535-","A48536-","C48537-","T48538-","A48539-","A48540-","C48541-","A48542-","C48543-","A48544-","A48545-","G48546-","A48547-","T48548-","G48549-","A48550-","A48551-","A48552-","A48553-","A48554-","T48555-","T48556-","T48557-","T48558-","T48559-","A48560-","G48561-","A48562-","G48563-","G48564-","T48565-","T48566-","G48567-","C48568-","C48569-","G48570-","A48571-","A48572-","T48573-","A48574-","C48575-","A48576-","T48577-","G48578-","G48579-","A48580-","C48581-","G48582-","A48583-","A48584-","T48585-","T48586-","A48587-","G48588-","G48589-","A48590-","G48591-","A48592-","A48593-","C48594-","T48595-","T48596-","A48597-","T48598-","A48599-","G48600-","G48601-","C48602-","G48603-","T48604-","A48605-","A48606-","A48607-","T48608-","T48609-","A48610-","T48611-","G48612-","A48613-","C48614-","T48615-","T48616-","A48617-","G48618-","T48619-","T48620-","C48621-","T48622-","T48623-","A48624-","A48625-","T48626-","C48627-","C48628-","A48629-","T48630-","T48631-","A48632-","T48633-","T48634-","T48635-","C48636-","A48637-","C48638-","G48639-","G48640-","A48641-","G48642-","G48643-","G48644-","G48645-","A48646-","A48647-","C48648-","C48649-","C48650-","A48651-","T48652-","C48653-","A48654-","A48655-","A48656-","G48657-","A48658-","T48659-","A48660-","T48661-","G48662-","G48663-","A48664-","A48665-","A48666-","T48667-","C48668-","A48669-","T48670-","T48671-","T48672-","T48673-","T48674-","T48675-","T48676-","A48677-","A48678-","A48679-","A48680-","C48681-","T48682-","G48683-","T48684-","T48685-","T48686-","A48687-","A48688-","G48689-","A48690-","A48691-","A48692-","A48693-","C48694-","A48695-","G48696-","A48697-","C48698-","T48699-","T48700-","C48701-","A48702-","A48703-","A48704-","G48705-","T48706-","T48707-","G48708-","T48709-","T48710-","A48711-","A48712-","A48713-","A48714-","A48715-","A48716-","T48717-","T48718-","A48719-","A48720-","G48721-","T48722-","G48723-","T48724-","T48725-","A48726-","T48727-","A48728-","A48729-","G48730-","A48731-","T48732-","T48733-","A48734-","C48735-","T48736-","T48737-","A48738-","T48739-","T48740-","T48741-","G48742-","G48743-","G48744-","C48745-","A48746-","T48747-","A48748-","C48749-","C48750-","T48751-","A48752-","A48753-","G48754-","C48755-","A48756-","A48757-","G48758-","A48759-","A48760-","A48761-","G48762-","A48763-","T48764-","A48765-","C48766-","A48767-","G48768-","G48769-","C48770-","A48771-","T48772-","A48773-","G48774-","A48775-","G48776-","T48777-","T48778-","T48779-","G48780-","C48781-","G48782-","G48783-","A48784-","T48785-","A48786-","A48787-","T48788-","G48789-","A48790-","T48791-","A48792-","G48793-","A48794-","C48795-","A48796-","A48797-","G48798-","A48799-","T48800-","A48801-","T48802-","A48803-","T48804-","A48805-","T48806-","A48807-","C48808-","T48809-","C48810-","T48811-","A48812-","T48813-","T48814-","T48815-","C48816-","A48817-","A48818-","C48819-","A48820-","A48821-","A48822-","C48823-","T48824-","G48825-","G48826-","T48827-","A48828-","G48829-","A48830-","A48831-","T48832-","A48833-","G48834-","T48835-","C48836-","C48837-","A48838-","T48839-","A48840-","G48841-","C48842-","A48843-","A48844-","T48845-","C48846-","T48847-","A48848-","A48849-","C48850-","A48851-","G48852-","A48853-","A48854-","A48855-","C48856-","G48857-","T48858-","T48859-","T48860-","A48861-","G48862-","G48863-","G48864-","A48865-","T48866-","T48867-","A48868-","T48869-","A48870-","T48871-","C48872-","T48873-","T48874-","T48875-","C48876-","C48877-","C48878-","G48879-","G48880-","A48881-","G48882-","A48883-","T48884-","A48885-","A48886-","G48887-","A48888-","C48889-","T48890-","A48891-","G48892-","C48893-","T48894-","A48895-","T48896-","T48897-","G48898-","G48899-","G48900-","T48901-","G48902-","T48903-","G48904-","G48905-","T48906-","T48907-","A48908-","A48909-","A48910-","C48911-","G48912-","A48913-","A48914-","A48915-","G48916-","T48917-","A48918-","T48919-","A48920-","G48921-","C48922-","T48923-","A48924-","A48925-","T48926-","G48927-","A48928-","T48929-","G48930-","C48931-","G48932-","G48933-","A48934-","T48935-","A48936-","T48937-","C48938-","G48939-","T48940-","T48941-","A48942-","T48943-","T48944-","A48945-","A48946-","T48947-","A48948-","G48949-","A48950-","C48951-","C48952-","C48953-","G48954-","C48955-","C48956-","A48957-","T48958-","T48959-","A48960-","C48961-","C48962-","A48963-","T48964-","G48965-","T48966-","A48967-","T48968-","G48969-","A48970-","T48971-","A48972-","A48973-","A48974-","A48975-","T48976-","T48977-","C48978-","T48979-","T48980-","A48981-","G48982-","T48983-","T48984-","A48985-","T48986-","A48987-","T48988-","A48989-","T48990-","A48991-","C48992-","T48993-","C48994-","T48995-","G48996-","A48997-","G48998-","A48999-","T49000-","A49001-","A49002-","A49003-","A49004-","C49005-","A49006-","G49007-","G49008-","G49009-","A49010-","C49011-","G49012-","C49013-","G49014-","T49015-","T49016-","A49017-","A49018-","T49019-","A49020-","A49021-","A49022-","A49023-","A49024-","C49025-","A49026-","T49027-","G49028-","C49029-","T49030-","T49031-","A49032-","A49033-","G49034-","T49035-","T49036-","A49037-","G49038-","T49039-","T49040-","T49041-","A49042-","T49043-","A49044-","T49045-","C49046-","T49047-","T49048-","T49049-","G49050-","A49051-","G49052-","C49053-","C49054-","T49055-","G49056-","A49057-","A49058-","A49059-","A49060-","A49061-","G49062-","A49063-","T49064-","A49065-","T49066-","C49067-","A49068-","G49069-","A49070-","G49071-","A49072-","A49073-","C49074-","T49075-","T49076-","C49077-","T49078-","G49079-","C49080-","T49081-","A49082-","G49083-","A49084-","A49085-","A49086-","T49087-","C49088-","A49089-","T49090-","A49091-","T49092-","A49093-","T49094-","G49095-","A49096-","T49097-","A49098-","T49099-","T49100-","C49101-","C49102-","T49103-","G49104-","G49105-","A49106-","G49107-","A49108-","T49109-","A49110-","T49111-","C49112-","C49113-","T49114-","A49115-","T49116-","C49117-","T49118-","A49119-","T49120-","T49121-","A49122-","T49123-","T49124-","G49125-","A49126-","T49127-","G49128-","C49129-","A49130-","A49131-","A49132-","A49133-","A49134-","A49135-","C49136-","G49137-","A49138-","C49139-","G49140-","A49141-","T49142-","T49143-","G49144-","G49145-","A49146-","A49147-","A49148-","A49149-","A49150-","A49151-","T49152-","A49153-","T49154-","T49155-","T49156-","T49157-","A49158-","T49159-","T49160-","A49161-","G49162-","T49163-","T49164-","T49165-","T49166-","T49167-","A49168-","C49169-","A49170-","A49171-","A49172-","G49173-","C49174-","T49175-","A49176-","A49177-","T49178-","T49179-","T49180-","T49181-","A49182-","T49183-","T49184-","A49185-","A49186-","C49187-","G49188-","G49189-","T49190-","A49191-","A49192-","T49193-","A49194-","C49195-","A49196-","T49197-","T49198-","T49199-","A49200-","T49201-","T49202-","A49203-","G49204-","T49205-","G49206-","A49207-","T49208-","A49209-","G49210-","A49211-","A49212-","C49213-","G49214-","T49215-","T49216-","T49217-","A49218-","A49219-","C49220-","G49221-","A49222-","T49223-","G49224-","A49225-","C49226-","T49227-","T49228-","A49229-","T49230-","T49231-","C49232-","A49233-","G49234-","A49235-","G49236-","T49237-","T49238-","G49239-","T49240-","T49241-","G49242-","T49243-","T49244-","C49245-","A49246-","A49247-","A49248-","T49249-","A49250-","G49251-","A49252-","T49253-","C49254-","C49255-","C49256-","G49257-","A49258-","A49259-","T49260-","A49261-","T49262-","T49263-","T49264-","C49265-","G49266-","A49267-","T49268-","A49269-","A49270-","T49271-","G49272-","A49273-","A49274-","C49275-","G49276-","A49277-","A49278-","T49279-","T49280-","A49281-","T49282-","G49283-","T49284-","C49285-","T49286-","T49287-","T49288-","A49289-","T49290-","T49291-","C49292-","T49293-","A49294-","T49295-","A49296-","C49297-","G49298-","A49299-","G49300-","T49301-","G49302-","C49303-","T49304-","G49305-","C49306-","G49307-","G49308-","A49309-","C49310-","A49311-","T49312-","T49313-","A49314-","A49315-","A49316-","C49317-","G49318-","A49319-","T49320-","T49321-","T49322-","G49323-","A49324-","T49325-","G49326-","A49327-","G49328-","T49329-","T49330-","A49331-","G49332-","A49333-","T49334-","A49335-","T49336-","T49337-","A49338-","A49339-","T49340-","A49341-","A49342-","C49343-","A49344-","G49345-","T49346-","T49347-","A49348-","T49349-","A49350-","T49351-","A49352-","T49353-","C49354-","T49355-","A49356-","A49357-","T49358-","A49359-","T49360-","A49361-","A49362-","T49363-","T49364-","T49365-","A49366-","T49367-","G49368-","A49369-","G49370-","G49371-","T49372-","G49373-","A49374-","A49375-","C49376-","G49377-","A49378-","T49379-","A49380-","T49381-","C49382-","A49383-","C49384-","A49385-","T49386-","T49387-","A49388-","G49389-","A49390-","T49391-","A49392-","C49393-","A49394-","A49395-","T49396-","G49397-","G49398-","A49399-","T49400-","G49401-","A49402-","T49403-","A49404-","T49405-","G49406-","A49407-","A49408-","G49409-","A49410-","A49411-","G49412-","T49413-","G49414-","T49415-","C49416-","A49417-","A49418-","A49419-","T49420-","C49421-","T49422-","T49423-","T49424-","A49425-","A49426-","C49427-","G49428-","A49429-","G49430-","G49431-","A49432-","T49433-","A49434-","C49435-","G49436-","T49437-","T49438-","G49439-","T49440-","A49441-","T49442-","T49443-","A49444-","T49445-","G49446-","T49447-","T49448-","A49449-","A49450-","G49451-","G49452-","A49453-","A49454-","T49455-","A49456-","C49457-","A49458-","A49459-","T49460-","A49461-","C49462-","A49463-","T49464-","A49465-","C49466-","C49467-","T49468-","G49469-","T49470-","T49471-","T49472-","T49473-","T49474-","G49475-","C49476-","A49477-","C49478-","G49479-","A49480-","G49481-","T49482-","C49483-","G49484-","G49485-","A49486-","T49487-","C49488-","C49489-","C49490-","A49491-","T49492-","G49493-","G49494-","T49495-","C49496-","A49497-","T49498-","A49499-","G49500-","A49501-","G49502-","A49503-","A49504-","C49505-","G49506-","G49507-","A49508-","A49509-","T49510-","A49511-","C49512-","T49513-","A49514-","A49515-","A49516-","G49517-","A49518-","A49519-","A49520-","C49521-","T49522-","G49523-","T49524-","C49525-","A49526-","T49527-","C49528-","T49529-","A49530-","T49531-","A49532-","A49533-","A49534-","A49535-","T49536-","C49537-","C49538-","A49539-","A49540-","G49541-","A49542-","G49543-","T49544-","A49545-","G49546-","A49547-","C49548-","G49549-","G49550-","C49551-","T49552-","G49553-","A49554-","A49555-","C49556-","T49557-","T49558-","G49559-","T49560-","T49561-","T49562-","A49563-","G49564-","C49565-","A49566-","A49567-","A49568-","A49569-","A49570-","C49571-","A49572-","T49573-","T49574-","T49575-","T49576-","A49577-","A49578-","A49579-","A49580-","T49581-","A49582-","T49583-","T49584-","A49585-","T49586-","T49587-","T49588-","A49589-","G49590-","A49591-","C49592-","G49593-","G49594-","A49595-","C49596-","A49597-","A49598-","T49599-","T49600-","G49601-","G49602-","C49603-","T49604-","C49605-","G49606-","T49607-","C49608-","T49609-","A49610-","G49611-","G49612-","T49613-","C49614-","T49615-","T49616-","G49617-","T49618-","G49619-","T49620-","T49621-","A49622-","G49623-","A49624-","T49625-","G49626-","A49627-","T49628-","T49629-","A49630-","T49631-","A49632-","A49633-","A49634-","G49635-","G49636-","A49637-","G49638-","A49639-","C49640-","T49641-","T49642-","A49643-","T49644-","T49645-","A49646-","G49647-","T49648-","T49649-","A49650-","A49651-","A49652-","A49653-","T49654-","G49655-","A49656-","T49657-","A49658-","A49659-","A49660-","C49661-","C49662-","A49663-","T49664-","C49665-","T49666-","C49667-","A49668-","A49669-","A49670-","T49671-","C49672-","T49673-","G49674-","T49675-","G49676-","G49677-","A49678-","G49679-","A49681-","T49682-","G49683-","T49684-","A49685-","T49686-","C49687-","C49688-","G49689-","C49690-","A49691-","T49692-","T49693-","C49694-","G49695-","T49696-","T49697-","A49698-","G49699-","A49700-","T49701-","T49702-","T49703-","T49704-","C49705-","T49706-","A49707-","C49708-","A49709-","A49711-","T49712-","G61626-","A61627-","G61628-","C61629-","T61630-","T61631-","A61674-","A61675-","T61676-","C61677-","G61678-","G61679-","A61680-","G61681-","A61682-","A61683-","T61684-","G61685-","T61686-","T61687-","T61688-","C61689-","C61690-","C61691-","A61692-","T61693-","T61694-","T61695-","T61696-","T61697-","A61698-","G61699-","G61700-","A61701-","T61702-","T61703-","A61704-","A61705-","C61706-","A61707-","T61708-","A61709-","G61710-","T61740-","A61741-","G61742-","T61743-","T61744-","A61764-","T61765-","T61766-","T61767-","G61768-","A61769-","T61770-","A61771-","A61791-","A61792-","T61793-","G61794-","G61795-","C61796-","A61797-","T61798-","A61799-","A61800-","T61801-","C61802-","C61803-","G61804-","G61805-","A61806-","T61807-","G61808-","T61809-","T61810-","G61811-","T61812-","G61813-","T61814-","A61815-","G61816-","T61817-","A61818-","C61819-","A61820-","A61821-","G61822-","T61823-","G61824-","G61825-","C61826-","T61827-","G61828-","C61829-","T61830-","A61831-","T61832-","T61833-","T61834-","C61835-","G61836-","G61837-","C61838-","T61839-","G61840-","C61841-","C61842-","A61843-","G61844-","A61845-","G61846-","T61847-","G61848-","T61849-","C61850-","C61851-","A61852-","A61853-","T61854-","T61855-","C61856-","T61857-","A61858-","C61859-","C61860-","G61861-","T61862-","T61863-","G61864-","T61865-","T61866-","A61867-","C61868-","T61869-","C61870-","C61871-","A61872-","T61873-","T61874-","A61875-","T61876-","A61877-","T61878-","A61879-","T61880-","T61881-","C61882-","C61883-","T61884-","T61885-","G61886-","A61887-","A61888-","T61889-","A61890-","A61891-","C61892-","C61893-","T61894-","T61895-","C61896-","A61897-","T61898-","A61899-","G61900-","C61901-","T61902-","A61903-","T61904-","T61905-","T61906-","T61907-","A61908-","A61909-","T61910-","A61911-","G61912-","G61913-","A61914-","T61915-","C61916-","T61917-","A61918-","T61919-","A61920-","T61921-","G61922-","A61923-","T61924-","C61925-","A61926-","G61927-","T61928-","G61929-","T61930-","T61931-","T61932-","A61933-","A61934-","G61935-","C61936-","C61937-","A61938-","T61939-","A61940-","G61941-","C61942-","A61943-","C61944-","A61945-","A61946-","T61947-","T61948-","T61949-","T61950-","C61951-","T61952-","A61953-","A61954-","T61955-","A61956-","C61957-","G61958-","A61959-","G61960-","A61961-","C61962-","G61963-","T61964-","G61965-","A61966-","T61967-","T61968-","T61969-","T61970-","A61971-","T61972-","C61973-","A61974-","A61975-","A61976-","C61977-","A61978-","T61979-","G61980-","A61981-","C61982-","A61983-","T61984-","T61985-","T61986-","T61987-","C61988-","C61989-","T61990-","T61991-","G61992-","T61993-","A61994-","T61995-","C61996-","C61997-","A61998-","T61999-","T62000-","T62001-","C62002-","G62003-","T62004-","T62005-","T62006-","A62007-","A62008-","T62009-","G62010-","A62011-","C62012-","A62013-","A62014-","A62015-","C62016-","A62017-","T62018-","T62019-","T62020-","T62021-","T62022-","G62023-","T62024-","T62025-","G62026-","G62027-","T62028-","G62029-","T62030-","A62031-","A62032-","T62033-","A62034-","A62035-","A62036-","A62037-","A62038-","A62039-","A62040-","A62041-","T62042-","T62043-","A62044-","T62045-","T62046-","T62047-","A62048-","A62049-","T62050-","T62051-","T62052-","T62053-","T62054-","C62055-","A62056-","T62057-","T62058-","A62059-","A62060-","T62061-","A62062-","G62063-","G62064-","G62065-","A62066-","T62067-","T62068-","T62069-","G62070-","A62071-","C62072-","G62073-","T62074-","A62075-","T62076-","G62077-","T62078-","A62079-","G62080-","C62081-","G62082-","T62083-","A62084-","C62085-","A62086-","A62087-","A62088-","A62089-","T62090-","T62091-","A62092-","T62093-","C62094-","G62095-","T62096-","T62097-","C62098-","C62099-","T62100-","G62101-","G62102-","T62103-","A62104-","T62105-","A62106-","T62107-","A62108-","A62152-","A62153-","C62154-","T62155-","T62156-","T62157-","A62158-","A62159-","T62160-","G62161-","A62162-","T62163-","T62164-","G62165-","T62631-","T62632-","T62633-","A62634-","G62635-","G62636-","A62637-","A62638-","T62639-","G62640-","T62641-","A62642-","T62643-","G62644-","G62645-","A62646-","C62647-","T62648-","C62649-","G62650-","C62651-","G62652-","T62653-","T62654-","T62655-","A62656-","G62657-","A62658-","G62659-","G62660-","A62661-","G62662-","T62663-","G62664-","A62665-","A62666-","C62667-","G62668-","T62669-","C62670-","T62671-","T62672-","C62673-","G62674-","G62675-","A62676-","G62677-","T62678-","A62679-","G62680-","T62681-","A62682-","A62683-","A62684-","G62685-","G62686-","A62687-","T62688-","G62689-","A62690-","T62691-","T62692-","C62693-","G62694-","T62695-","C62696-","A62697-","A62698-","A62699-","T62700-","G62701-","A62702-","A63505-","A63506-","G88521-","A88522-","T88523-","C88524-","T88525-","C88526-","T88527-","A88528-","T88529-","A88530-","A88531-","T88532-","A88533-","T88534-","C88535-","T88536-","A88537-","G88538-","T88539-","T88540-","T88541-","C88542-","T88543-","T88544-","G88545-","C88546-","G88547-","T88548-","T88549-","T88550-","C88551-","A88552-","C88553-","A88554-","A88555-","A88556-","C88557-","A88558-","C88559-","A88560-","G88561-","G88562-","C88563-","T88564-","C88565-","G88566-","T88567-","C88568-","T88569-","C88570-","T88571-","C88572-","G88573-","C88574-","G88575-","A88576-","T88577-","G88578-","A88579-","G88580-","A88581-","T88582-","C88583-","T88584-","G88585-","T88586-","A88587-","T88588-","A88589-","G88590-","T88591-","A88592-","A88593-","C88594-","T88595-","A88596-","T88597-","G88598-","T88599-","A88600-","A88601-","A88602-","T88603-","G88604-","A88605-","T88606-","A88607-","A88608-","C88609-","T88610-","A88611-","G88612-","A88613-","T88614-","A88615-","G88616-","A88617-","A88618-","A88619-","G88620-","A88621-","T88622-","G88623-","T88624-","A88625-","G88626-","C88627-","T88628-","A88629-","T88630-","A88631-","T88632-","A88633-","G88634-","A88635-","T88636-","G88637-","A88638-","C88639-","G88640-","A88641-","T88642-","C88643-","C88644-","T88645-","T88646-","T88647-","A88648-","A88649-","G88650-","A88651-","G88652-","A88653-","G88654-","G88655-","T88656-","A88657-","T88658-","A88659-","A88660-","T88661-","A88662-","A88663-","C88664-","T88665-","T88666-","T88667-","A88668-","C88669-","C88670-","C88671-","C88672-","A88673-","A88674-","T88675-","C88676-","A88677-","G88678-","A88679-","T88680-","A88681-","G88682-","A88683-","C88684-","T88685-","G88686-","T88687-","T88688-","G88689-","T88690-","T88691-","A88692-","T88693-","G88694-","G88695-","T88696-","C88697-","T88698-","T88699-","C88700-","G88701-","G88702-","A88703-","A88704-","A88705-","A88706-","A88707-","G88708-","A88709-","A88710-","T88711-","T88712-","T88713-","T88714-","T88715-","A88716-","T88717-","A88718-","A88719-","A88720-","T88721-","T88722-","T88723-","T88724-","T88725-","C88726-","C88727-","A88728-","G88729-","T88730-","A88731-","T88732-","T88733-","T88734-","T88735-","C88736-","T88737-","A88738-","A88739-","A88740-","T88741-","A88742-","T88743-","A88744-","C88745-","G88746-","T88747-","A88748-","C88749-","T88750-","T88751-","G88752-","A88753-","T88754-","A88755-","T88756-","C88757-","T88758-","A88759-","A88760-","G88761-","A88762-","A88763-","A88764-","T88765-","C88766-","C88767-","T88768-","T88769-","A88770-","A88771-","T88772-","A88773-","A88774-","T88775-","A88776-","A88777-","T88778-","A88779-","G88780-","G88781-","A88782-","A88783-","T88784-","G88785-","G88786-","A88787-","T88788-","A88789-","A88790-","T88791-","C88792-","C88793-","G88794-","T88795-","C88796-","T88797-","A88798-","T88799-","T88800-","T88801-","T88802-","A88803-","T88804-","A88805-","A88806-","A88807-","G88808-","A88809-","A88810-","A88811-","T88812-","A88813-","C88814-","A88815-","T88816-","A88817-","T88818-","C88819-","G88820-","C88821-","A88822-","T88823-","A88824-","T88825-","T88826-","A88827-","T88828-","A88829-","C88830-","T88831-","T88832-","T88833-","T88834-","T88835-","T88836-","T88837-","T88838-","G88839-","G88840-","A88841-","A88842-","A88843-","T88844-","T88845-","G88846-","G88847-","A88848-","A88849-","T88850-","A88851-","C88852-","C88853-","G88854-","A88855-","T88856-","G88857-","T88858-","G88859-","T88860-","C88861-","T88862-","A88863-","C88864-","A88865-","T88866-","A88867-","A88868-","A88869-","T88870-","A88871-","C88872-","G88873-","C88874-","A88875-","A88876-","A88877-","G88878-","T88879-","C88880-","T88881-","A88882-","A88883-","A88884-","T88885-","A88886-","T88887-","T88888-","T88889-","T88890-","T88891-","T88892-","A88893-","G88894-","A88895-","G88896-","A88897-","A88898-","T88899-","C88900-","T88901-","T88902-","A88903-","G88904-","T88905-","T88906-","G88907-","G88908-","T88909-","C88910-","C88911-","A88912-","A88913-","A88914-","T88915-","T88916-","C88917-","T88918-","T88919-","T88920-","T88921-","C88922-","C88923-","A88924-","A88925-","G88926-","T88927-","A88928-","C88929-","G88930-","G88931-","T88932-","A88933-","A88934-","T88935-","A88936-","G88937-","A88938-","T88939-","T88940-","T88941-","T88942-","T88943-","C88944-","A88945-","T88946-","A88947-","T88948-","T88949-","G88950-","A88951-","A88952-","C88953-","G88954-","G88955-","T88956-","A88957-","T88958-","C88959-","T88960-","T88961-","C88962-","T88963-","T88964-","G88965-","A88966-","T88967-","C88968-","T88969-","C88970-","T88971-","G88972-","G88973-","T88974-","T88975-","C88976-","T88977-","A88978-","A88979-","T88980-","T88981-","C88982-","C88983-","G88984-","C88985-","A88986-","T88987-","T88988-","A88989-","A88990-","A88991-","T88992-","G88993-","A88994-","T88995-","G88996-","A88997-","A88998-","A88999-","C89000-","T89001-","A89002-","A89003-","G89004-","T89005-","C89006-","A89007-","C89008-","T89009-","A89010-","T89011-","T89012-","T89013-","T89014-","T89015-","A89016-","T89017-","A89018-","A89019-","C89020-","T89021-","A89022-","A89023-","C89024-","G89025-","A89026-","T89027-","T89028-","A89029-","C89030-","A89031-","T89032-","C89033-","A89034-","C89035-","C89036-","T89037-","C89038-","T89039-","A89040-","A89041-","C89042-","A89043-","T89044-","C89045-","A89046-","T89047-","C89048-","A89049-","T89050-","T89051-","T89052-","A89053-","C89054-","C89055-","A89056-","G89057-","G89058-","A89059-","T89060-","A89061-","C89062-","T89063-","G89064-","A89065-","T89066-","C89067-","T89068-","T89069-","C89070-","T89071-","T89072-","T89073-","T89074-","G89075-","T89076-","C89077-","G89078-","T89079-","A89080-","A89081-","A89082-","T89083-","A89084-","C89085-","A89086-","T89087-","G89088-","T89089-","C89090-","T89091-","A89092-","A89093-","T89094-","G89095-","T89096-","G89097-","T89098-","T89099-","A89100-","A89101-","A89102-","A89103-","A89104-","A89105-","A89106-","A89107-","G89108-","A89109-","T89110-","C89111-","A89112-","T89113-","A89114-","C89115-","A89116-","A89117-","G89118-","T89119-","T89120-","A89121-","T89122-","A89123-","C89124-","G89125-","T89126-","C89127-","A89128-","T89129-","T89130-","T89131-","C89132-","A89133-","T89134-","C89135-","T89136-","G89137-","T89138-","A89139-","G89140-","T89141-","A89142-","T89143-","T89144-","C89145-","T89146-","T89147-","G89148-","T89149-","C89150-","A89151-","T89152-","T89153-","G89154-","A89155-","A89156-","G89157-","G89158-","A89159-","T89160-","A89161-","A89162-","A89163-","C89164-","T89165-","T89166-","G89167-","T89168-","A89169-","C89170-","T89171-","A89172-","A89173-","T89174-","C89175-","T89176-","C89177-","T89178-","T89179-","C89180-","T89181-","T89182-","T89183-","A89184-","A89185-","C89186-","A89187-","G89188-","T89189-","C89190-","T89191-","G89192-","T89193-","T89194-","C89195-","A89196-","A89197-","A89198-","T89199-","T89200-","T89201-","A89202-","T89203-","A89204-","T89205-","C89206-","C89207-","T89208-","A89209-","T89210-","A89211-","T89212-","A89213-","T89214-","G89215-","A89216-","A89217-","A89218-","A89219-","A89220-","A89221-","T89222-","A89223-","G89224-","C89225-","A89226-","A89227-","C89228-","C89229-","A89230-","G89231-","T89232-","G89233-","T89234-","T89235-","T89236-","G89237-","A89238-","T89239-","C89240-","A89241-","T89242-","C89243-","C89244-","G89245-","C89246-","G89247-","T89248-","C89249-","A89250-","A89251-","T89252-","A89253-","T89254-","T89255-","C89256-","T89257-","G89258-","T89259-","T89260-","C89261-","T89262-","A89263-","T89264-","C89265-","G89266-","T89267-","A89268-","G89269-","T89270-","G89271-","T89272-","A89273-","T89274-","A89275-","A89276-","C89277-","A89278-","A89279-","T89280-","C89281-","T89282-","T89283-","A89284-","T89285-","A89286-","T89287-","C89288-","T89289-","T89290-","C89291-","T89292-","T89293-","C89294-","T89295-","G89296-","T89297-","G89298-","A89299-","T89300-","A89301-","G89302-","T89303-","C89304-","G89305-","A89306-","T89307-","A89308-","C89309-","G89310-","T89311-","T89312-","A89313-","T89314-","A89315-","A89316-","A89317-","G89318-","G89319-","T89320-","T89321-","G89322-","A89323-","T89324-","A89325-","A89326-","C89327-","G89328-","A89329-","A89330-","A89331-","A89332-","T89333-","A89334-","T89335-","T89336-","T89337-","T89338-","T89339-","A89340-","T89341-","T89342-","T89343-","C89344-","G89345-","T89346-","G89347-","A89348-","A89349-","A89350-","T89351-","A89352-","A89353-","A89354-","G89355-","T89356-","C89357-","A89358-","T89359-","T89360-","G89361-","T89362-","A89363-","G89364-","G89365-","A89366-","T89367-","T89368-","T89369-","T89370-","G89371-","G89372-","A89373-","C89374-","T89375-","T89376-","A89377-","T89378-","A89379-","T89380-","T89381-","C89382-","G89383-","T89384-","G89385-","T89386-","C89387-","T89388-","A89389-","G89390-","T89391-","A89392-","G89393-","A89394-","T89395-","A89396-","T89397-","G89398-","A89399-","T89400-","T89401-","T89402-","T89403-","A89404-","T89405-","T89406-","T89407-","T89408-","T89409-","G89410-","G89411-","A89412-","A89413-","T89414-","G89415-","A89416-","T89417-","C89418-","T89419-","C89420-","A89421-","A89422-","T89423-","T89424-","A89425-","A89426-","A89427-","A89428-","T89429-","A89430-","G89431-","T89432-","C89433-","T89434-","C89435-","T89436-","T89437-","T89438-","A89439-","G89440-","A89441-","G89442-","T89443-","C89444-","C89445-","A89446-","T89447-","T89448-","T89449-","A89450-","A89451-","A89452-","G89453-","T89454-","T89455-","A89456-","C89457-","A89458-","A89459-","A89460-","C89461-","A89462-","A89463-","C89464-","T89465-","A89466-","G89467-","G89468-","A89469-","A89470-","A89471-","T89472-","T89473-","G89474-","G89475-","T89476-","T89477-","T89478-","A89479-","T89480-","G89481-","A89482-","T89483-","G89484-","T89485-","A89486-","T89487-","A89488-","A89489-","T89490-","T89491-","T89492-","T89493-","T89494-","T89495-","T89496-","A89497-","G89498-","T89499-","T89500-","T89501-","T89502-","T89503-","A89504-","T89505-","A89506-","G89507-","A89508-","T89509-","T89510-","C89511-","T89512-","T89513-","T89514-","A89515-","T89516-","T89517-","C89518-","T89519-","A89520-","T89521-","A89522-","C89523-","T89524-","T89525-","A89526-","A89527-","A89528-","A89529-","A89530-","A89531-","T89532-","G89533-","A89534-","A89535-","A89536-","A89537-","T89538-","A89539-","A89540-","A89541-","T89542-","A89543-","C89544-","A89545-","A89546-","A89547-","G89548-","G89549-","T89550-","T89551-","C89552-","T89553-","T89554-","G89555-","A89556-","G89557-","G89558-","G89559-","T89560-","T89561-","G89562-","T89563-","G89564-","T89565-","T89566-","A89567-","A89568-","T89569-","T89570-","G89571-","A89572-","A89573-","A89574-","G89575-","C89576-","G89577-","A89578-","T89579-","A89580-","A89581-","A89582-","T89583-","A89584-","A89585-","T89586-","C89587-","A89588-","T89589-","A89590-","A89591-","A89592-","T89593-","T89594-","A89595-","T89596-","T89597-","T89598-","C89599-","A89600-","T89601-","T89602-","A89603-","T89604-","C89605-","G89606-","C89607-","G89608-","A89609-","T89610-","A89611-","T89612-","C89613-","C89614-","G89615-","T89616-","T89617-","A89618-","A89619-","G89620-","T89621-","T89622-","T89623-","G89624-","T89625-","A89626-","T89627-","C89628-","G89629-","T89630-","A89631-","A89632-","T89633-","G89634-","G89635-","C89636-","G89637-","T89638-","G89639-","G89640-","T89641-","C89642-","A89643-","A89644-","T89645-","T89646-","A89647-","C89648-","G89649-","A89650-","A89651-","T89652-","A89653-","A89654-","A89655-","G89656-","C89657-","G89658-","G89659-","A89660-","T89661-","A89662-","C89663-","T89664-","A89665-","G89666-","T89667-","A89668-","G89669-","T89670-","T89671-","T89672-","C89673-","A89674-","C89675-","A89676-","A89677-","A89678-","G89679-","A89680-","T89681-","G89682-","G89683-","C89684-","T89685-","G89686-","A89687-","A89688-","A89689-","T89690-","C89691-","A89692-","G89693-","A89694-","G89695-","C89696-","T89697-","C89698-","A89699-","T89700-","C89701-","T89702-","A89703-","A89704-","G89705-","A89706-","A89707-","A89708-","T89709-","A89710-","G89711-","C89712-","G89713-","C89714-","T89715-","G89716-","A89717-","A89718-","A89719-","A89720-","T89721-","A89722-","A89723-","A89724-","G89725-","A89726-","T89727-","A89728-","A89729-","A89730-","A89731-","A89732-","C89733-","G89734-","A89735-","G89736-","G89737-","A89738-","T89739-","A89740-","T89741-","T89742-","T89743-","T89744-","C89745-","C89746-","C89747-","G89748-","G89749-","A89750-","A89751-","G89752-","A89753-","T89754-","G89755-","T89756-","A89757-","A89758-","T89759-","A89760-","A89761-","T89762-","T89763-","C89764-","C89765-","A89766-","T89767-","C89768-","T89769-","A89770-","C89771-","T89772-","A89773-","A89774-","G89775-","C89776-","C89777-","C89778-","A89779-","A89780-","A89781-","A89782-","C89783-","C89784-","A89785-","A89786-","A89787-","C89788-","G89789-","A89790-","A89791-","C89792-","C89793-","A89794-","C89795-","T89796-","A89797-","C89798-","T89799-","C89800-","C89801-","T89802-","C89803-","G89804-","T89805-","A89806-","A89807-","A89808-","C89809-","C89810-","A89811-","G89812-","C89813-","G89814-","G89815-","C89816-","T89817-","A89818-","C89819-","T89820-","A89821-","A89822-","A89823-","A89824-","G89825-","A89826-","T89827-","C89828-","A89829-","A89830-","C89831-","C89832-","A89833-","A89834-","A89835-","A89836-","A89837-","G89838-","G89839-","A89840-","T89841-","A89842-","A89843-","A89844-","G89845-","A89846-","A89847-","A89848-","A89849-","G89850-","G89851-","A89852-","G89853-","G89854-","A89855-","A89856-","G89857-","T89858-","G89859-","G89860-","A89861-","A89862-","G89863-","A89864-","A89865-","G89866-","T89867-","A89868-","G89869-","T89870-","T89871-","A89872-","T89873-","A89874-","G89875-","A89876-","G89877-","G89878-","A89879-","A89880-","T89881-","A89882-","T89883-","C89884-","A89885-","T89886-","C89887-","A89888-","A89889-","A89890-","C89891-","A89892-","A89893-","C89894-","T89895-","G89896-","A89897-","A89898-","G89899-","A89900-","A89901-","A89902-","A89903-","T89904-","T89905-","C89906-","T89907-","C89908-","C89909-","A89910-","C89911-","C89912-","T89913-","C89914-","C89915-","G89916-","T89917-","C89918-","A89919-","T89920-","C89921-","A89922-","T89923-","C89924-","T89925-","C89926-","C89927-","T89928-","G89929-","G89930-","A89931-","G89932-","T89933-","C89934-","G89935-","G89936-","C89937-","G89938-","A89939-","C89940-","A89941-","T89942-","T89943-","G89944-","T89945-","A89946-","G89947-","A89948-","A89949-","A89950-","G89951-","C89952-","G89953-","T89954-","G89955-","G89956-","C89957-","C89958-","G89959-","C89960-","T89961-","G89962-","T89963-","A89964-","G89965-","A89966-","G89967-","C89968-","T89969-","C89970-","G89971-","A89972-","T89973-","G89974-","A89975-","T89976-","A89977-","G89978-","C89979-","G89980-","A89981-","C89982-","G89983-","G89984-","G89985-","G89986-","A89987-","T89988-","G89989-","A89990-","T89991-","G89992-","A89993-","A89994-","C89995-","C89996-","T89997-","A89998-","T89999-","G90000-","G90001-","T90002-","A90003-","C90004-","A90005-","A90006-","G90007-","T90008-","T90009-","G90010-","A90011-","A90012-","G90013-","C90014-","T90015-","G90016-","G90017-","T90018-","A90019-","A90020-","A90021-","G90022-","T90023-","A90024-","A90025-","A90026-","T90027-","C90028-","A90029-","T90030-","A90031-","G90032-","T90033-","G90034-","C90035-","T90036-","A90037-","G90038-","A90039-","A90040-","G90041-","C90042-","G90043-","A90044-","T90045-","C90046-","T90047-","C90048-","T90049-","C90050-","T90051-","G90052-","A90053-","C90054-","C90055-","T90056-","A90057-","A90058-","A90059-","G90060-","G90061-","T90062-","G90063-","G90064-","C90065-","T90066-","A90067-","C90068-","C90069-","G90070-","A90071-","C90072-","A90073-","A90074-","T90075-","A90076-","T90077-","C90078-","G90079-","T90080-","T90081-","A90082-","A90083-","A90084-","G90085-","A90086-","T90087-","C90088-","T90089-","T90090-","A90091-","A90092-","G90093-","A90094-","A90095-","A90096-","A90097-","T90098-","T90099-","A90100-","T90101-","T90102-","A90103-","C90104-","T90105-","A90106-","G90107-","A90108-","A90109-","T90110-","C90111-","T90112-","C90113-","T90114-","G90115-","C90116-","A90117-","G90118-","T90119-","A90120-","T90121-","C90122-","G90123-","A90124-","C90125-","T90126-","G90127-","T90128-","T90129-","C90130-","T90131-","A90132-","G90133-","A90134-","G90135-","G90136-","A90137-","T90138-","G90139-","T90140-","T90141-","C90142-","A90143-","A90144-","G90145-","C90146-","A90147-","G90148-","C90149-","T90150-","G90151-","G90152-","T90153-","A90154-","T90155-","C90156-","T90157-","C90158-","T90159-","A90160-","G90161-","A90162-","C90163-","A90164-","A90165-","T90166-","T90167-","T90168-","A90169-","C90170-","T90171-","T90172-","C90173-","T90174-","A90175-","T90176-","G90177-","A90178-","C90179-","T90180-","A90181-","A90182-","A90183-","G90184-","C90185-","T90186-","A90187-","T90188-","T90189-","A90190-","C90191-","A90192-","A90193-","C90194-","A90195-","C90196-","T90197-","A90198-","T90199-","C90200-","T90201-","G90202-","A90203-","T90204-","C90205-","T90206-","A90207-","G90208-","T90209-","C90210-","A90211-","C90212-","C90213-","G90214-","A90215-","G90216-","G90217-","G90218-","A90219-","A90220-","A90221-","A90222-","T90223-","C90224-","T90225-","A90226-","A90227-","A90228-","G90229-","T90230-","T90231-","G90232-","T90233-","T90234-","C90235-","G90236-","T90237-","A90238-","A90239-","A90240-","A90241-","A90242-","A90243-","G90244-","T90245-","T90246-","A90247-","A90248-","A90249-","A90250-","C90251-","T90252-","T90253-","G90254-","T90255-","A90256-","A90257-","G90258-","A90259-","A90260-","G90261-","T90262-","A90263-","A90264-","A90265-","T90266-","G90267-","C90268-","G90269-","T90270-","G90271-","C90272-","A90273-","C90274-","T90275-","T90276-","T90277-","T90278-","T90279-","T90280-","A90281-","T90282-","A90283-","A90284-","A90285-","G90286-","A90287-","T90288-","G90289-","G90290-","T90291-","A90292-","A90293-","A90294-","C90295-","T90296-","G90297-","T90298-","T90299-","T90300-","A90301-","C90302-","C90303-","G90304-","A90305-","T90306-","A90307-","A90308-","T90309-","A90310-","A90311-","T90312-","T90313-","T90314-","T90315-","T90316-","T90317-","A90318-","A90319-","A90320-","T90321-","C90322-","C90323-","T90324-","G90325-","T90326-","A90327-","T90328-","C90329-","A90330-","G90331-","A90332-","C90333-","G90334-","A90335-","T90336-","A90337-","A90338-","T90339-","C90340-","C90341-","A90342-","G90343-","C90344-","G90345-","T90346-","A90347-","T90348-","G90349-","A90350-","G90351-","G90352-","T90353-","T90354-","T90355-","T90356-","G90357-","C90358-","A90359-","A90360-","C90361-","A90362-","T90363-","G90364-","T90365-","T90366-","A90367-","A90368-","A90369-","A90370-","T90371-","T90372-","C90373-","C90374-","T90375-","A90376-","C90377-","T90378-","C90379-","A90380-","T90381-","T90382-","T90383-","A90384-","A90385-","C90386-","A90387-","G90388-","A90389-","T90390-","G90391-","T90392-","A90393-","G90394-","T90395-","A90396-","G90397-","T90398-","A90399-","T90400-","A90401-","T90402-","G90403-","A90404-","A90405-","C90406-","A90407-","A90408-","A90409-","C90410-","G90411-","T90412-","G90413-","G90414-","G90415-","A90416-","A90417-","G90418-","A90419-","G90420-","G90421-","C90422-","A90423-","T90424-","T90425-","A90426-","A90427-","C90428-","T90429-","A90430-","G90431-","A90432-","T90433-","T90434-","A90435-","A90436-","T90437-","T90438-","T90439-","T90440-","T90441-","G90442-","T90443-","G90444-","G90445-","G90446-","A90447-","A90448-","G90449-","T90450-","G90451-","A90452-","T90453-","T90454-","C90455-","A90456-","A90457-","A90458-","A90459-","G90460-","G90461-","A90462-","C90463-","G90464-","T90465-","A90466-","G90467-","A90468-","C90469-","A90470-","A90471-","T90472-","A90473-","C90474-","T90475-","T90476-","T90477-","T90478-","A90479-","C90480-","G90481-","G90482-","A90483-","A90484-","A90485-","A90486-","A90487-","T90488-","G90489-","C90490-","A90491-","T90492-","A90493-","T90494-","A90495-","C90496-","A90497-","G90498-","A90499-","A90500-","T90501-","C90502-","G90503-","C90504-","A90505-","A90506-","T90507-","G90508-","C90509-","T90510-","A90511-","A90512-","A90513-","A90514-","G90515-","A90516-","G90517-","A90518-","T90519-","C90520-","G90521-","T90522-","A90523-","T90524-","T90525-","T90526-","T90527-","T90528-","G90529-","T90530-","T90531-","A90532-","G90533-","A90534-","G90535-","T90536-","A90537-","T90538-","A90539-","T90540-","A90541-","A90542-","C90543-","G90544-","T90545-","T90546-","A90547-","T90548-","G90549-","A90550-","A90551-","A90552-","C90553-","G90554-","A90555-","A90556-","T90557-","T90558-","A90559-","A90560-","T90561-","T90562-","G90563-","T90564-","T90565-","T90566-","T90567-","A90568-","T90569-","A90570-","A90571-","A90572-","C90573-","A90574-","A90575-","A90576-","A90577-","A90578-","T90579-","A90580-","T90581-","A90582-","A90583-","A90584-","G90585-","A90586-","A90587-","A90588-","T90589-","C90590-","G90591-","C151552T","C167451T","T172130-","T172131-","C172132-","C172133-","T173843-","A173844-","G173845-","T173846-","A173847-","A194548-","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","C194595-","G194596-","T194597-","G194598-","T194599-"],"OPG002":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-"],"OPG002_dup":["C44-","L45-","S46-","C47-"],"OPG057":["N267D"],"OPG080":["S84-","N85-"],"OPG178":["S15F"]},"labels":{"aa":"OPG002: K31-, C32-, K33-, D34-, N35-, E36-, Y37-; OPG002_dup: C44-, L45-, S46-, C47-; OPG057: N267D; OPG080: S84-, N85-; OPG178: S15F"}}}]}]},{"name":"NODE_0000103","node_attrs":{"div":563,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C18441T","G22415A","G70002A","C132698T","G143951A","C148604T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G154188A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG031":["E130K"],"OPG089":["R46K"],"OPG165":["D146N"],"OPG174":["M264I"]},"labels":{"aa":"OPG031: E130K; OPG089: R46K; OPG165: D146N; OPG174: M264I"}},"children":[{"name":"OR643708","node_attrs":{"div":565,"accession":"OR643708","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00553/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-07-28"},"strain_display":{"value":"USA/OR643708/2023-07-28"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G70425A","C137966T"],"OPG089":["G187E"],"OPG154":["E29K"]},"labels":{"aa":"OPG089: G187E; OPG154: E29K"}}},{"name":"OR643700","node_attrs":{"div":566,"accession":"OR643700","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00558/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-08-24"},"strain_display":{"value":"USA/OR643700/2023-08-24"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C96773T","A166129G","G168741A"],"OPG117":["S242L"],"OPG195":["R171K"]},"labels":{"aa":"OPG117: S242L; OPG195: R171K"}}},{"name":"OR499974","node_attrs":{"div":563,"accession":"OR499974","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00517/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-06-20"},"strain_display":{"value":"USA/OR499974/2023-06-20"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000104","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.16"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C9389T","C30154T","G161797A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","A185557C"],"OPG188":["E68K"],"OPG210":["K1401T"]},"labels":{"aa":"OPG188: E68K; OPG210: K1401T","clade":"B.1.16"}},"children":[{"name":"OP459211","node_attrs":{"div":561,"accession":"OP459211","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.16"},"strain":{"value":"ANT-LDSP-ANT-MPX-23596-O"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-29"},"strain_display":{"value":"Colombia/OP459211/2022-08-29"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G170076A"]}}},{"name":"OP642383","node_attrs":{"div":561,"accession":"OP642383","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.16"},"strain":{"value":"ANT-LDSP-ANT-MPX-24909-C"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-09"},"strain_display":{"value":"Colombia/OP642383/2022-09-09"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G6863A","C132608T"]}}},{"name":"OP693647","node_attrs":{"div":560,"accession":"OP693647","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.16"},"strain":{"value":"DC_INS_MPX_0082_L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-08"},"strain_display":{"value":"Colombia/OP693647/2022-08-08"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["A1701-","C1702-","T1703-","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-","T196852-","G196853-","T196854-"]}}},{"name":"NODE_0000105","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.16"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G148403A","-180517A","-180518A","-180519T","-180520G","-180521A","-180522C","-180523G","-180524A","-180525T","-180526A","-180527T","-180528A","-180529C","-180530G","-180531G","-180532A","-180533T","-180534T"],"OPG187":["R267K"]},"labels":{"aa":"OPG187: R267K"}},"children":[{"name":"OP837481","node_attrs":{"div":563,"accession":"OP837481","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.16"},"strain":{"value":"VAC_INS_MPX_1050_C"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-26"},"strain_display":{"value":"Colombia/OP837481/2022-10-26"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G69840A","G161421A","C196636-","T196637-","C196638-"]}}},{"name":"OQ148473","node_attrs":{"div":562,"accession":"OQ148473","author":{"author":"Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"country":{"value":"Colombia"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.16"},"strain":{"value":"LBMB-UTP_MP-021_VAC"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-11"},"strain_display":{"value":"Colombia/OQ148473/2022-11-11"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C133212-","C133213-","T133214-","C133215-","G133216-","A133217-","G133218-","T133219-","C133220-","T133221-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","C188896T"]}}}]}]},{"name":"NODE_0000106","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C170573T"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}},"children":[{"name":"OQ451902","node_attrs":{"div":562,"accession":"OQ451902","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/RKI717"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"Germany/OQ451902/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","C3602T","C53342T","C124495T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159789A","G190695A","G193608A"],"OPG003":["E336K"],"OPG003_dup":["E336K"],"OPG016":["E96K"],"OPG071":["R366K"]},"labels":{"aa":"OPG003: E336K; OPG003_dup: E336K; OPG016: E96K; OPG071: R366K"}}},{"name":"OR264459","node_attrs":{"div":559,"accession":"OR264459","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"7_A"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-11"},"strain_display":{"value":"Australia/OR264459/2022-07-11"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["C25644T","G144556A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"NODE_0000107","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N"}},"children":[{"name":"OR759146","node_attrs":{"div":560,"accession":"OR759146","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Canada/ON-PHOL053/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759146/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C3405T","G5375A","C191835T","G193805A"],"OPG015":["A261V"],"OPG015_dup":["A261V"]},"labels":{"aa":"OPG015: A261V; OPG015_dup: A261V"}}},{"name":"NODE_0000108","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C188391T"]}},"children":[{"name":"OP879761","node_attrs":{"div":559,"accession":"OP879761","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"country":{"value":"USA"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"NJ-MPXV-047"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-21"},"strain_display":{"value":"USA/OP879761/2022-07-21"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"OR353575","node_attrs":{"div":562,"accession":"OR353575","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"country":{"value":"USA"},"institution":{"value":"Minnesota Department of Health, Public Health Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MN-MDH-MPXV_0065"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-30"},"strain_display":{"value":"USA/OR353575/2022-08-30"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","C8392T","A20156G","G170867A","T196741-","A196742-","T196743-"],"OPG198":["R277K"]},"labels":{"aa":"OPG198: R277K"}}}]}]}]},{"name":"NODE_0000109","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C118453T","G137276A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177009A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","A196614-"],"OPG136":["E379K"],"OPG153":["S131F"],"OPG205":["E452K"]},"labels":{"aa":"OPG136: E379K; OPG153: S131F; OPG205: E452K"}},"children":[{"name":"NODE_0000110","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C117119T"]}},"children":[{"name":"OQ330972","node_attrs":{"div":561,"accession":"OQ330972","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00372/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-18"},"strain_display":{"value":"USA/OQ330972/2022-10-18"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A763-","A764-","T765-","C128294T","A196675-","T196676-","G196677-"]}}},{"name":"OR499971","node_attrs":{"div":562,"accession":"OR499971","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00514/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-05-04"},"strain_display":{"value":"USA/OR499971/2023-05-04"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T39397C","T178873C","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG057":["N267D"]},"labels":{"aa":"OPG057: N267D"}}}]},{"name":"NODE_0000111","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G635-","A636-","A637-","A1697-","G39327A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T195519-"],"OPG057":["A290V"]},"labels":{"aa":"OPG057: A290V"}},"children":[{"name":"OQ331006","node_attrs":{"div":560,"accession":"OQ331006","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00397/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-03"},"strain_display":{"value":"USA/OQ331006/2023-01-03"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-1697A","-179265C","-179266A","-179267T","-179268G","-179269G","-179270A","-179271T","-179272A","-179273T","-179274C","-179275T","-179276T","-179277T","-179278A","-179279A","-179280A","-179281G","-179282A","-179283A","-179284C","-179285T","-179286A","-179287A","-179288T","-179289C","-179290T","-179291T","-179292A","-179293A","-179294A","-179295A","-179296C","-179297A","-179298T","-179299A","-179300C","-179301G","-179302G","-179303A","-179304T","-179305G","-179306A","-179307A","-179308A","-179309A","-179310T","-179311G","-179312T","-179313T","-179314T","-179315T","-179316G","-179317A","-179318T","-179319T","-179320T","-179321C","-179322T","-179323C","-179324C","-179325A","-179326G","-179327T","-179328T","-179329T","-179330C","-179331C","-179332A","-179333T","-179334T","-179335T","-179336T","-179337A","-179338T","-179339C","-179340T","-179341A","-179342C","-179343T","-179344T","-179345T","-179346A","-179347T","-179348C","-179349T","-179350A","-179351T","-179352T","-179353C","-195519T","T196627-","C196628-","T196629-"]}}},{"name":"OR499967","node_attrs":{"div":560,"accession":"OR499967","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00510/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-05-04"},"strain_display":{"value":"USA/OR499967/2023-05-04"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A672-","C673-","A674-","T196633-","C196634-","T196635-"]}}},{"name":"OR499948","node_attrs":{"div":560,"accession":"OR499948","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00491/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-04-10"},"strain_display":{"value":"USA/OR499948/2023-04-10"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000117","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C43706T","T124690C","C141757T"]},"labels":{"clade":"B.1.18"}},"children":[{"name":"OP628451","node_attrs":{"div":559,"accession":"OP628451","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"strain":{"value":"MpxV/human/USA/WA-UW-083401/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP628451/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP722512","node_attrs":{"div":559,"accession":"OP722512","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00253/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-11"},"strain_display":{"value":"USA/OP722512/2022-10-11"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ121025","node_attrs":{"div":559,"accession":"OQ121025","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,Bell,J.,Hacker,J."},"country":{"value":"USA"},"institution":{"value":"CDPH, VRDL"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"strain":{"value":"hMpxV/USA/CA-CDPH-1000071/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-06"},"strain_display":{"value":"USA/OQ121025/2022-07-06"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ721920","node_attrs":{"div":561,"accession":"OQ721920","author":{"author":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"strain":{"value":"MPXV_USA_2022_IL0009"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721920/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","G78759A","C126911T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","A196614-"],"OPG101":["E92K"],"OPG148":["S309F"]},"labels":{"aa":"OPG101: E92K; OPG148: S309F"}}},{"name":"NODE_0000118","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C170049T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A"]}},"children":[{"name":"OR464199","node_attrs":{"div":565,"accession":"OR464199","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"strain":{"value":"MPXV_USA_2022_NY0051"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OR464199/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C45127T","G91787A","G91880A","G105147A","C114521T"],"OPG064":["E258K"],"OPG133":["M392I"]},"labels":{"aa":"OPG064: E258K; OPG133: M392I"}}},{"name":"NODE_0000119","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G67758A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP819956","node_attrs":{"div":562,"accession":"OP819956","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"strain":{"value":"VAC_INS_MPX_0965_EL"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-12"},"strain_display":{"value":"Colombia/OP819956/2022-10-12"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G28913A"],"OPG045":["S117L"]},"labels":{"aa":"OPG045: S117L"}}},{"name":"OQ148474","node_attrs":{"div":565,"accession":"OQ148474","author":{"author":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"country":{"value":"Colombia"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.18"},"strain":{"value":"LBMB-UTP_MP-025_VAC"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-15"},"strain_display":{"value":"Colombia/OQ148474/2022-11-15"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C128242T","G144572A","C166940T","C168829T"],"OPG150":["S155F"],"OPG166":["A59T"]},"labels":{"aa":"OPG150: S155F; OPG166: A59T"}}}]}]}]},{"name":"NODE_0000120","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G181367A","A196614-"]},"labels":{"clade":"B.1.9"}},"children":[{"name":"ON843175","node_attrs":{"div":557,"accession":"ON843175","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0043/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Portugal/ON843175/2022-05-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP693652","node_attrs":{"div":558,"accession":"OP693652","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"strain":{"value":"DC_INS_MPX_0718_L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-16"},"strain_display":{"value":"Colombia/OP693652/2022-08-16"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["-606T","G134122T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP687938","node_attrs":{"div":560,"accession":"OP687938","author":{"author":"Gigante,C.M.,Acheampong,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Morrison,S.S.,Seabolt,M.H.,Weigand,M.R.,Knipe,K.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,McDermott,D.,Li,Y.","value":"Gigante,C.M.,Acheampong,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Morrison,S.S.,Seabolt,M.H.,Weigand,M.R.,Knipe,K.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,McDermott,D.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"strain":{"value":"MPXV_USA_2022_NJ0005"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP687938/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G61329A","C101868T","C103427T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG121":["P27S"]},"labels":{"aa":"OPG121: P27S"}}},{"name":"NODE_0000121","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G176823A"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG205":["E390K"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG205: E390K"}},"children":[{"name":"ON880538","node_attrs":{"div":559,"accession":"ON880538","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"strain":{"value":"MpxV/human/CAN/UN-NML-3336/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-01"},"strain_display":{"value":"Canada/ON880538/2022-06-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-11326A","-11327T","-11328C","-11329T","-11330A","-11331C","-11332G","-11333A","-11334T","-11335A","-11336T","-11337T","-11338A","-11339G","-11340A","-11341T","-11342A","-11343C","-11344T","-11345T","-11346C","-11347A","-11348C","-11349T","-11350C","-11351A","-11352A","-11353T","-11354G","-11355A","-11356A","-11357T","-11358C","-11359A","-11360A","-11361T","-11362C","-11363A","-11364C","-11365A","-11366C","-11367A","-11368A","-11369T","-11370C","-11371T","-11372A","-11373A","-11374T","-11375G","-11376T","-11377A","-11378G","-11379G","-11380T","-11381T","-11382T","-11383A","-11384T","-11385G","-11386A","-11387C","-11388A","-11389T","-11390A","-11391A","-11392T","-11393A","-11394G","-11395C","-11396A","-11397T","-11398T","-11399T","-11400T","-11401C","-11402A","-11403G","-11404C","-11405A","-11406G","-11407T","-11408T","-11409C","-11410A","-11411A","-11412T","-11413G","-11414T","-11415T","-11416T","-11417C","-11418T","-11419A","-11420G","-11421A","-11422T","-11423T","-11424C","-11425G","-11426T","-11427T","-11428G","-11429A","-11430T","-11431G","-11432G","-11433C","-11434A","-11435A","-11436T","-11437G","-11438G","-11439T","-11440T","-11441A","-11442T","-11443A","-11444C","-11445A","-11446T","-11447G","-11448T","-11449A","-11450T","-11451A","-11452T","-11453C","-11454C","-11455G","-11456T","-11457T","-11458A","-11459T","-11460T","-11461T","-11462G","-11463A","-11464T","-11465C","-11466T","-11467A","-11468A","-11469T","-11470G","-11471T","-11472T","-11473G","-11474A","-11475C","-11476A","-11477T","-11478C","-11479T","-11480G","-11481A","-11482A","-11483C","-11484C","-11485G","-11486G","-11487A","-11488T","-11489T","-11490C","-11491T","-11492A","-11493G","-11494C","-11495A","-11496G","-11497T","-11498A","-11499A","-11500A","-11501G","-11502A","-11503T","-11504A","-11505C","-11506T","-11507A","-11508G","-11509A","-11510G","-11511A","-11512T","-11513T","-11514G","-11515T","-11516T","-11517T","-11518A","-11519T","-11520T","-11521A","-11522T","-11523A","-11524T","-11525C","-11526T","-11527A","-11528A","-11529C","-11530A","-11531G","-11532C","-11533C","-11534T","-11535T","-11536G","-11537T","-11538G","-11539A","-11540A","-11541G","-11542A","-11543A","-11544G","-11545T","-11546G","-11547T","-11548T","-11549T","-11550C","-11551T","-11552C","-11553C","-11554T","-11555C","-11556G","-11557T","-11558T","-11559T","-11560G","-11561T","-11562C","-11563A","-11564A","-11565T","-11566C","-11567A","-11568T","-11569G","-11570T","-11571T","-11572A","-11573A","-11574T","-11575G","-11576T","-11577C","-11578T","-11579T","-11580T","-11581A","-11582A","-11583G","-11584A","-11585T","-11586A","-11587A","-11588G","-11589G","-11590T","-11591A","-11592G","-11593A","-11594C","-11595A","-11596A","-11597A","-11598T","-11599G","-11600T","-11601T","-11602T","-11603A","-11604T","-11605A","-11606G","-11607T","-11608A","-11609C","-11610T","-11611A","-11612A","-11613G","-11614A","-11615A","-11616T","-11617T","-11618G","-11619G","-11620G","-11621C","-11622A","-11623A","-11624A","-11625C","-11626A","-11627T","-11628A","-11629A","-11630G","-11631A","-11632C","-11633A","-11634T","-11635G","-11636T","-11637C","-11638A","-11639C","-11640A","-11641A","-11642A","-11643G","-11644A","-11645C","-11646C","-11647C","-11648T","-11649T","-11650T","-11651T","-11652T","-11653G","-11654T","-11655A","-11656T","-11657G","-11658T","-11659A","-11660T","-11661A","-11662A","-11663G","-11664T","-11665G","-11666T","-11667A","-11668G","-11669A","-11670A","-11671A","-11672T","-11673T","-11674A","-11675T","-11676A","-11677A","-11678C","-11679A","-11680T","-11681C","-11682C","-11683A","-11684T","-11685A","-11686G","-11687T","-11688T","-11689G","-11690G","-11691A","-11692T","-11693T","-11694C","-11695A","-11696C","-11697A","-11698T","-11699A","-11700G","-11701G","-11702T","-11703G","-11704T","-11705C","-11706C","-11707A","-11708A","-11709T","-11710C","-11711G","-11712G","-11713G","-11714A","-11715T","-11716C","-11717T","-11718C","-11719T","-11720C","-11721C","-11722A","-11723T","-11724C","-11725A","-11726T","-11727C","-11728G","-11729A","-11730G","-11731A","-11732T","-11733G","-11734A","-11735T","-11736T","-11737G","-11738A","-11739C","-11740G","-11741G","-11742C","-11743A","-11744T","-11745C","-11746T","-11747C","-11748C","-11749C","-11750C","-11751C","-11752T","-11753T","-11754C","-11755C","-11756T","-11757T","-11758T","-11759T","-11760T","-11761T","-11762A","-11763G","-11764T","-11765A","-11766G","-11767A","-11768T","-11769A","-11770T","-11771T","-11772T","-11773C","-11774A","-11775T","-11776C","-11777G","-11778T","-11779G","-11780T","-11781A","-11782A","-11783G","-11784A","-11785A","-11786T","-11787C","-11788A","-11789A","-11790T","-11791A","-11792T","-11793T","-11794A","-11795A","-11796T","-11797A","-11798T","-11799T","-11800T","-11801C","-11802T","-11803A","-11804A","-11805A","-11806G","-11807T","-11808A","-11809T","-11810C","-11811T","-11812G","-11813T","-11814G","-11815T","-11816A","-11817T","-11818A","-11819G","-11820C","-11821C","-11822T","-11823C","-11824T","-11825T","-11826T","-11827A","-11828T","-11829T","-11830T","-11831A","-11832C","-11833C","-11834A","-11835C","-11836A","-11837G","-11838C","-11839T","-11840C","-11841C","-11842A","-11843T","-11844A","-11845T","-11846T","-11847C","-11848C","-11849A","-11850A","-11851C","-11852A","-11853T","-11854G","-11855C","-11856A","-11857T","-11858T","-11859C","-11860C","-11861A","-11862C","-11863T","-11864A","-11865G","-11866A","-11867G","-11868G","-11869G","-11870A","-11871T","-11872A","-11873T","-11874C","-11875G","-11876A","-11877T","-11878A","-11879T","-11880C","-11881G","-11882C","-11883C","-11884G","-11885A","-11886A","-11887T","-11888G","-11889T","-11890C","-11891A","-11892T","-11893A","-11894T","-11895A","-11896C","-11897T","-11898C","-11899A","-11900A","-11901T","-11902T","-11903A","-11904G","-11905T","-11906A","-11907T","-11908A","-11909T","-11910G","-11911T","-11912T","-11913G","-11914G","-11915A","-11916G","-11917G","-11918A","-11919C","-11920A","-11921T","-11922C","-11923C","-11924G","-11925A","-11926G","-11927T","-11928T","-11929C","-11930A","-11931T","-11932T","-11933G","-11934T","-11935T","-11936T","-11937T","-11938C","-11939A","-11940A","-11941T","-11942A","-11943T","-11944C","-11945A","-11946A","-11947A","-11948G","-11949A","-11950G","-11951A","-11952T","-11953G","-11954G","-11955T","-11956T","-11957T","-11958C","-11959C","-11960T","-11961T","-11962A","-11963T","-11964C","-11965A","-11966T","-11967T","-11968T","-11969C","-11970T","-11971C","-11972C","-11973A","-11974T","-11975A","-11976G","-11977T","-11978G","-11979G","-11980T","-11981A","-11982C","-11983A","-11984A","-11985T","-11986A","-11987C","-11988T","-11989A","-11990C","-11991A","-11992C","-11993A","-11994T","-11995T","-11996A","-11997T","-11998T","-11999C","-12000C","-12001G","-12002T","-12003A","-12004C","-12005G","-12006G","-12007C","-12008T","-12009T","-12010T","-12011C","-12012C","-12013A","-12014T","-12015T","-12016C","-12017T","-12018C","-12019C","-12020A","-12021A","-12022A","-12023A","-12024A","-12025C","-12026A","-12027A","-12028T","-12029T","-12030T","-12031T","-12032A","-12033C","-12034C","-12035A","-12036A","-12037A","-12038T","-12039C","-12040T","-12041A","-12042A","-12043A","-12044T","-12045C","-12046T","-12047A","-12048C","-12049A","-12050T","-12051C","-12052T","-12053T","-12054T","-12055A","-12056T","-12057T","-12058G","-12059T","-12060A","-12061T","-12062C","-12063T","-12064A","-12065T","-12066A","-12067A","-12068T","-12069C","-12070A","-12071C","-12072T","-12073A","-12074T","-12075T","-12076T","-12077A","-12078G","-12079A","-12080T","-12081A","-12082A","-12083T","-12084C","-12085A","-12086G","-12087C","-12088C","-12089A","-12090T","-12091A","-12092A","-12093T","-12094T","-12095C","-12096C","-12097T","-12098C","-12099G","-12100A","-12101G","-12102T","-12103G","-12104C","-12105A","-12106A","-12107C","-12108A","-12109T","-12110G","-12111T","-12112T","-12113A","-12114G","-12115A","-12116T","-12117C","-12118G","-12119T","-12120C","-12121T","-12122A","-12123T","-12124A","-12125T","-12126A","-12127T","-12128G","-12129A","-12130A","-12131T","-12132A","-12133A","-12134G","-12135C","-12136C","-12137G","-12138T","-12139G","-12140T","-12141T","-12142A","-12143T","-12144C","-12145T","-12146A","-12147T","-12148T","-12149C","-12150C","-12151T","-12152T","-12153T","-12154C","-12155A","-12156T","-12157T","-12158A","-12159A","-12160C","-12161A","-12162A","-12163T","-12164T","-12165T","-12166A","-12167A","-12168C","-12169G","-12170A","-12171T","-12172G","-12173T","-12174C","-12175T","-12176A","-12177T","-12178A","-12179T","-12180C","-12181T","-12182A","-12183T","-12184A","-12185T","-12186G","-12187A","-12188G","-12189A","-12190T","-12191G","-12192A","-12193C","-12194T","-12195T","-12196A","-12197A","-12198T","-12199A","-12200T","-12201A","-12202A","-12203T","-12204A","-12205T","-12206T","-12207G","-12208A","-12209A","-12210G","-12211A","-12212G","-12213C","-12214T","-12215G","-12216T","-12217A","-12218C","-12219A","-12220A","-12221T","-12222A","-12223G","-12224T","-12225T","-12226T","-12227T","-12228T","-12229A","-12230T","-12231C","-12232T","-12233A","-12234T","-12235A","-12236G","-12237A","-12238A","C32627T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"],"OPG023":["-222S","-223I","-224D","-225K","-226N","-227Y","-228C","-229T","-230A","-231L","-232Q","-233Y","-234Y","-235I","-236K","-237S","-238S","-239H","-240I","-241D","-242I","-243D","-244I","-245V","-246K","-247L","-248L","-249M","-250K","-251G","-252I","-253D","-254N","-255T","-256A","-257Y","-258S","-259Y","-260I","-261D","-262D","-263L","-264T","-265C","-266C","-267T","-268R","-269G","-270I","-271M","-272A","-273D","-274Y","-275L","-276N","-277S","-278D","-279Y","-280R","-281Y","-282N","-283K","-284D","-285V","-286D","-287L","-288D","-289L","-290V","-291K","-292L","-293F","-294L","-295E","-296N","-297G","-298K","-299P","-300Y","-301G","-302I","-303M","-304C","-305S","-306I","-307V","-308P","-309L","-310W","-311R","-312N","-313D","-314K","-315E","-316T","-317I","-318S","-319L","-320I","-321L","-322K","-323T","-324M","-325N","-326S","-327D","-328V","-329L","-330Q","-331H","-332I","-333L","-334I","-335E","-336Y","-337M","-338T","-339F","-340G","-341D","-342I","-343D","-344I","-345P","-346L","-347V","-348E","-349C","-350M","-351L","-352E","-353Y","-354G","-355A","-356V","-357V","-358N","-359K","-360E","-361A","-362I","-363H","-364R","-365Y","-366F","-367R","-368N","-369I","-370N","-371I","-372D","-373S","-374Y","-375T","-376M","-377K","-378Y","-379L","-380L","-381K","-382K","-383E","-384G","-385G","-386D","-387A","-388V","-389N","-390H","-391L","-392D","-393D","-394G","-395E","-396I","-397P","-398I","-399G","-400H","-401L","-402C","-403E","-404S","-405N","-406Y","-407G","-408C","-409Y","-410N","-411F","-412Y","-413T","-414Y","-415T","-416Y","-417K","-418K","-419G","-420L","-421C","-422D","-423M","-424S","-425Y","-426V","-427C","-428P","-429I","-430L","-431S","-432T","-433I","-434N","-435I","-436C","-437L","-438P","-439Y","-440L","-441K","-442D","-443I","-444N","-445M","-446I","-447D","-448K","-449R","-450G","-451E","-452T","-453L","-454L","-455H","-456K","-457A","-458V","-459R","-460Y","-461N","-462K","-463Q","-464S","-465L","-466V","-467S","-468L","-469L","-470L","-471E","-472S","-473G","-474S","-475D","-476V","-477N","-478I","-479R","-480S","-481N","-482N","-483G","-484Y","-485T","-486C","-487I","-488T","-489I","-490A","-491I","-492N","-493E","-494S","-495R","-496N","-497I","-498E","-499L","-500L","-501K","-502M","-503L","-504L","-505C","-506H","-507K","-508P","-509T","-510L","-511D","-512C","-513V","-514I","-515D","-516S","-517L","-518S","-519E","-520V","-521S","-522N","-523I","-524V","-525D"]},"labels":{"aa":"OPG023: -222S, -223I, -224D, -225K, -226N, -227Y, -228C, -229T, -230A, -231L, -232Q, -233Y, -234Y, -235I, -236K, -237S, -238S, -239H, -240I, -241D, -242I, -243D, -244I, -245V, -246K, -247L, -248L, -249M, -250K, -251G, -252I, -253D, -254N, -255T, -256A, -257Y, -258S, -259Y, -260I, -261D, -262D, -263L, -264T, -265C, -266C, -267T, -268R, -269G, -270I, -271M, -272A, -273D, -274Y, -275L, -276N, -277S, -278D, -279Y, -280R, -281Y, -282N, -283K, -284D, -285V, -286D, -287L, -288D, -289L, -290V, -291K, -292L, -293F, -294L, -295E, -296N, -297G, -298K, -299P, -300Y, -301G, -302I, -303M, -304C, -305S, -306I, -307V, -308P, -309L, -310W, -311R, -312N, -313D, -314K, -315E, -316T, -317I, -318S, -319L, -320I, -321L, -322K, -323T, -324M, -325N, -326S, -327D, -328V, -329L, -330Q, -331H, -332I, -333L, -334I, -335E, -336Y, -337M, -338T, -339F, -340G, -341D, -342I, -343D, -344I, -345P, -346L, -347V, -348E, -349C, -350M, -351L, -352E, -353Y, -354G, -355A, -356V, -357V, -358N, -359K, -360E, -361A, -362I, -363H, -364R, -365Y, -366F, -367R, -368N, -369I, -370N, -371I, -372D, -373S, -374Y, -375T, -376M, -377K, -378Y, -379L, -380L, -381K, -382K, -383E, -384G, -385G, -386D, -387A, -388V, -389N, -390H, -391L, -392D, -393D, -394G, -395E, -396I, -397P, -398I, -399G, -400H, -401L, -402C, -403E, -404S, -405N, -406Y, -407G, -408C, -409Y, -410N, -411F, -412Y, -413T, -414Y, -415T, -416Y, -417K, -418K, -419G, -420L, -421C, -422D, -423M, -424S, -425Y, -426V, -427C, -428P, -429I, -430L, -431S, -432T, -433I, -434N, -435I, -436C, -437L, -438P, -439Y, -440L, -441K, -442D, -443I, -444N, -445M, -446I, -447D, -448K, -449R, -450G, -451E, -452T, -453L, -454L, -455H, -456K, -457A, -458V, -459R, -460Y, -461N, -462K, -463Q, -464S, -465L, -466V, -467S, -468L, -469L, -470L, -471E, -472S, -473G, -474S, -475D, -476V, -477N, -478I, -479R, -480S, -481N, -482N, -483G, -484Y, -485T, -486C, -487I, -488T, -489I, -490A, -491I, -492N, -493E, -494S, -495R, -496N, -497I, -498E, -499L, -500L, -501K, -502M, -503L, -504L, -505C, -506H, -507K, -508P, -509T, -510L, -511D, -512C, -513V, -514I, -515D, -516S, -517L, -518S, -519E, -520V, -521S, -522N, -523I, -524V, -525D"}}},{"name":"ON585038","node_attrs":{"div":559,"accession":"ON585038","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0008/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-15"},"strain_display":{"value":"Portugal/ON585038/2022-05-15"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C16968T","A188351-"]}}},{"name":"OP555485","node_attrs":{"div":560,"accession":"OP555485","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0389/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-12"},"strain_display":{"value":"Portugal/OP555485/2022-07-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-606T","C57110T","G159148A","-196614A"],"OPG074":["E6K"],"OPG185":["D78N"]},"labels":{"aa":"OPG074: E6K; OPG185: D78N"}}},{"name":"NODE_0000122","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C34432T"],"OPG053":["E87K"]},"labels":{"aa":"OPG053: E87K"}},"children":[{"name":"OP414351","node_attrs":{"div":561,"accession":"OP414351","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0319/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-04"},"strain_display":{"value":"Portugal/OP414351/2022-06-04"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G25534A","G96524A"],"OPG117":["R159K"]},"labels":{"aa":"OPG117: R159K"}}},{"name":"OP555631","node_attrs":{"div":562,"accession":"OP555631","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0560/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-30"},"strain_display":{"value":"Portugal/OP555631/2022-08-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T594A","-606T","-607T","-608T","-609T","-11326A","-11327T","-11328C","-11329T","-11330A","-11331C","-11332G","-11333A","-11334T","-11335A","-11336T","-11337T","-11338A","-11339G","-11340A","-11341T","-11342A","-11343C","-11344T","-11345T","-11346C","-11347A","-11348C","-11349T","-11350C","-11351A","-11352A","-11353T","-11354G","-11355A","-11356A","-11357T","-11358C","-11359A","-11360A","-11361T","-11362C","-11363A","-11364C","-11365A","-11366C","-11367A","-11368A","-11369T","-11370C","-11371T","-11372A","-11373A","-11374T","-11375G","-11376T","-11377A","-11378G","-11379G","-11380T","-11381T","-11382T","-11383A","-11384T","-11385G","-11386A","-11387C","-11388A","-11389T","-11390A","-11391A","-11392T","-11393A","-11394G","-11395C","-11396A","-11397T","-11398T","-11399T","-11400T","-11401C","-11402A","-11403G","-11404C","-11405A","-11406G","-11407T","-11408T","-11409C","-11410A","-11411A","-11412T","-11413G","-11414T","-11415T","-11416T","-11417C","-11418T","-11419A","-11420G","-11421A","-11422T","-11423T","-11424C","-11425G","-11426T","-11427T","-11428G","-11429A","-11430T","-11431G","-11432G","-11433C","-11434A","-11435A","-11436T","-11437G","-11438G","-11439T","-11440T","-11441A","-11442T","-11443A","-11444C","-11445A","-11446T","-11447G","-11448T","-11449A","-11450T","-11451A","-11452T","-11453C","-11454C","-11455G","-11456T","-11457T","-11458A","-11459T","-11460T","-11461T","-11462G","-11463A","-11464T","-11465C","-11466T","-11467A","-11468A","-11469T","-11470G","-11471T","-11472T","-11473G","-11474A","-11475C","-11476A","-11477T","-11478C","-11479T","-11480G","-11481A","-11482A","-11483C","-11484C","-11485G","-11486G","-11487A","-11488T","-11489T","-11490C","-11491T","-11492A","-11493G","-11494C","-11495A","-11496G","-11497T","-11498A","-11499A","-11500A","-11501G","-11502A","-11503T","-11504A","-11505C","-11506T","-11507A","-11508G","-11509A","-11510G","-11511A","-11512T","-11513T","-11514G","-11515T","-11516T","-11517T","-11518A","-11519T","-11520T","-11521A","-11522T","-11523A","-11524T","-11525C","-11526T","-11527A","-11528A","-11529C","-11530A","-11531G","-11532C","-11533C","-11534T","-11535T","-11536G","-11537T","-11538G","-11539A","-11540A","-11541G","-11542A","-11543A","-11544G","-11545T","-11546G","-11547T","-11548T","-11549T","-11550C","-11551T","-11552C","-11553C","-11554T","-11555C","-11556G","-11557T","-11558T","-11559T","-11560G","-11561T","-11562C","-11563A","-11564A","-11565T","-11566C","-11567A","-11568T","-11569G","-11570T","-11571T","-11572A","-11573A","-11574T","-11575G","-11576T","-11577C","-11578T","-11579T","-11580T","-11581A","-11582A","-11583G","-11584A","-11585T","-11586A","-11587A","-11588G","-11589G","-11590T","-11591A","-11592G","-11593A","-11594C","-11595A","-11596A","-11597A","-11598T","-11599G","-11600T","-11601T","-11602T","-11603A","-11604T","-11605A","-11606G","-11607T","-11608A","-11609C","-11610T","-11611A","-11612A","-11613G","-11614A","-11615A","-11616T","-11617T","-11618G","-11619G","-11620G","-11621C","-11622A","-11623A","-11624A","-11625C","-11626A","-11627T","-11628A","-11629A","-11630G","-11631A","-11632C","-11633A","-11634T","-11635G","-11636T","-11637C","-11638A","-11639C","-11640A","-11641A","-11642A","-11643G","-11644A","-11645C","-11646C","-11647C","-11648T","-11649T","-11650T","-11651T","-11652T","-11653G","-11654T","-11655A","-11656T","-11657G","-11658T","-11659A","-11660T","-11661A","-11662A","-11663G","-11664T","-11665G","-11666T","-11667A","-11668G","-11669A","-11670A","-11671A","-11672T","-11673T","-11674A","-11675T","-11676A","-11677A","-11678C","-11679A","-11680T","-11681C","-11682C","-11683A","-11684T","-11685A","-11686G","-11687T","-11688T","-11689G","-11690G","-11691A","-11692T","-11693T","-11694C","-11695A","-11696C","-11697A","-11698T","-11699A","-11700G","-11701G","-11702T","-11703G","-11704T","-11705C","-11706C","-11707A","-11708A","-11709T","-11710C","-11711G","-11712G","-11713G","-11714A","-11715T","-11716C","-11717T","-11718C","-11719T","-11720C","-11721C","-11722A","-11723T","-11724C","-11725A","-11726T","-11727C","-11728G","-11729A","-11730G","-11731A","-11732T","-11733G","-11734A","-11735T","-11736T","-11737G","-11738A","-11739C","-11740G","-11741G","-11742C","-11743A","-11744T","-11745C","-11746T","-11748C","-11749C","-11750C","-11751C","-11752T","-11753T","-11754C","-11755C","-11756T","-11757T","-11758T","-11759T","-11760T","-11761T","-11762A","-11763G","-11764T","-11765A","-11766G","-11767A","-11769A","-11770T","-11773C","-11828T","-11829T","-11830T","-11831A","-11836A","-11837G","-11838C","-11842A","-11843T","-11844A","-11845T","-11846T","-11847C","-11848C","-11849A","-11850A","-11851C","-11852A","-11853T","-11854G","-11855C","-11856A","-11857T","-11858T","-11859C","-11860C","-11861A","-11862C","-11863T","-11864A","-11865G","-11866A","-11867G","-11868G","-11869G","-11870A","-11871T","-11872A","-11873T","-11874C","-11875G","-11876A","-11877T","-11878A","-11879T","-11880C","-11881G","-11882C","-11883C","-11884G","-11885A","-11886A","-11887T","-11888G","-11889T","-11890C","-11891A","-11892T","-11893A","-11894T","-11895A","-11896C","-11897T","-11898C","-11899A","-11900A","-11901T","-11902T","-11903A","-11904G","-11905T","-11906A","-11907T","-11908A","-11909T","-11910G","-11911T","-11912T","-11913G","-11914G","-11915A","-11916G","-11917G","-11918A","-11919C","-11920A","-11921T","-11922C","-11923C","-11924G","-11925A","-11926G","-11927T","-11928T","-11929C","-11930A","-11931T","-11932T","-11933G","-11934T","-11935T","-11936T","-11937T","-11938C","-11939A","-11940A","-11941T","-11942A","-11943T","-11944C","-11945A","-11946A","-11947A","-11948G","-11949A","-11950G","-11951A","-11952T","-11953G","-11954G","-11955T","-11956T","-11957T","-11958C","-11959C","-11960T","-11961T","-11962A","-11963T","-11964C","-11965A","-11966T","-11967T","-11968T","-11969C","-11970T","-11971C","-11972C","-11973A","-11974T","-11975A","-11976G","-11977T","-11978G","-11979G","-11980T","-11981A","-11982C","-11983A","-11984A","-11985T","-11986A","-11987C","-11988T","-11989A","-11990C","-11991A","-11992C","-11993A","-11994T","-11995T","-11996A","-11997T","-11998T","-11999C","-12000C","-12001G","-12002T","-12003A","-12004C","-12005G","-12006G","-12007C","-12008T","-12009T","-12010T","-12011C","-12012C","-12013A","-12014T","-12015T","-12016C","-12017T","-12018C","-12019C","-12020A","-12021A","-12022A","-12023A","-12024A","-12025C","-12026A","-12027A","-12028T","-12029T","-12030T","-12031T","-12032A","-12033C","-12034C","-12035A","-12036A","-12037A","-12038T","-12039C","-12040T","-12041A","-12042A","-12043A","-12044T","-12045C","-12046T","-12047A","-12048C","-12049A","-12050T","-12051C","-12053T","-12054T","-12055A","-12056T","-12057T","-12058G","-12059T","-12060A","-12062C","-12063T","-12064A","-12065T","-12066A","-12067A","-12068T","-12069C","-12070A","-12071C","-12073A","-12074T","-12075T","-12076T","-12077A","-12078G","-12079A","-12080T","-12081A","-12082A","-12083T","-12084C","-12085A","-12187A","-12189A","-12190T","-12191G","-12192A","-12193C","-12194T","-12195T","-12196A","-12197A","-12198T","-12199A","-12200T","-12201A","-12202A","-12203T","-12204A","-12205T","-12206T","-12207G","-12208A","-12209A","-12210G","-12211A","-12212G","-12213C","-12214T","-12215G","-12216T","-12217A","-12218C","-12219A","-12220A","-12221T","-12222A","-12223G","-12224T","-12225T","-12226T","-12227T","-12228T","-12229A","-12230T","-12231C","-12232T","-12233A","-12234T","-12235A","-12236G","-12237A","C68792T","G119156A","G155157A","-196614A","-196615A","-196616T","-196617A"],"OPG023":["-222S","-223I","-224D","-225K","-226N","-227Y","-228C","-229T","-230A","-231L","-232Q","-233Y","-234Y","-235I","-236K","-237S","-273D","-274Y","-275L","-276N","-278D","-279Y","-281Y","-282N","-284D","-285V","-286D","-287L","-288D","-289L","-290V","-291K","-292L","-293F","-294L","-295E","-296N","-297G","-298K","-299P","-300Y","-301G","-302I","-303M","-304C","-305S","-306I","-307V","-308P","-309L","-310W","-311R","-312N","-313D","-314K","-315E","-316T","-317I","-318S","-319L","-320I","-321L","-322K","-323T","-324M","-325N","-326S","-327D","-328V","-329L","-330Q","-331H","-332I","-333L","-334I","-335E","-336Y","-337M","-338T","-339F","-340G","-341D","-342I","-343D","-344I","-345P","-346L","-347V","-348E","-349C","-350M","-351L","-352E","-353Y","-355A","-379L","-380L","-381K","-382K","-383E","-384G","-386D","-387A","-388V","-389N","-390H","-391L","-392D","-393D","-394G","-395E","-396I","-397P","-398I","-399G","-400H","-401L","-402C","-403E","-404S","-405N","-406Y","-407G","-408C","-409Y","-410N","-411F","-412Y","-413T","-414Y","-415T","-416Y","-417K","-418K","-419G","-420L","-421C","-422D","-423M","-424S","-425Y","-426V","-427C","-428P","-429I","-430L","-431S","-432T","-433I","-434N","-435I","-436C","-437L","-438P","-439Y","-440L","-441K","-442D","-443I","-444N","-445M","-446I","-447D","-448K","-449R","-450G","-451E","-452T","-453L","-454L","-455H","-456K","-457A","-458V","-459R","-460Y","-461N","-462K","-463Q","-464S","-465L","-466V","-467S","-468L","-469L","-470L","-471E","-472S","-473G","-474S","-475D","-476V","-477N","-478I","-479R","-480S","-481N","-482N","-483G","-484Y","-485T","-486C","-487I","-488T","-489I","-490A","-491I","-492N","-493E","-494S","-495R","-496N","-497I","-498E","-499L","-500L","-501K","-502M","-503L","-504L","-505C","-506H","-507K","-508P","-509T","-510L","-511D","-512C","-513V","-514I","-515D","-516S","-517L","-518S","-519E","-520V","-521S","-522N","-523I","-524V","-525D"],"OPG181":["R249K"]},"labels":{"aa":"OPG023: -222S, -223I, -224D, -225K, -226N, -227Y, -228C, -229T, -230A, -231L, -232Q, -233Y, -234Y, -235I, -236K, -237S, -273D, -274Y, -275L, -276N, -278D, -279Y, -281Y, -282N, -284D, -285V, -286D, -287L, -288D, -289L, -290V, -291K, -292L, -293F, -294L, -295E, -296N, -297G, -298K, -299P, -300Y, -301G, -302I, -303M, -304C, -305S, -306I, -307V, -308P, -309L, -310W, -311R, -312N, -313D, -314K, -315E, -316T, -317I, -318S, -319L, -320I, -321L, -322K, -323T, -324M, -325N, -326S, -327D, -328V, -329L, -330Q, -331H, -332I, -333L, -334I, -335E, -336Y, -337M, -338T, -339F, -340G, -341D, -342I, -343D, -344I, -345P, -346L, -347V, -348E, -349C, -350M, -351L, -352E, -353Y, -355A, -379L, -380L, -381K, -382K, -383E, -384G, -386D, -387A, -388V, -389N, -390H, -391L, -392D, -393D, -394G, -395E, -396I, -397P, -398I, -399G, -400H, -401L, -402C, -403E, -404S, -405N, -406Y, -407G, -408C, -409Y, -410N, -411F, -412Y, -413T, -414Y, -415T, -416Y, -417K, -418K, -419G, -420L, -421C, -422D, -423M, -424S, -425Y, -426V, -427C, -428P, -429I, -430L, -431S, -432T, -433I, -434N, -435I, -436C, -437L, -438P, -439Y, -440L, -441K, -442D, -443I, -444N, -445M, -446I, -447D, -448K, -449R, -450G, -451E, -452T, -453L, -454L, -455H, -456K, -457A, -458V, -459R, -460Y, -461N, -462K, -463Q, -464S, -465L, -466V, -467S, -468L, -469L, -470L, -471E, -472S, -473G, -474S, -475D, -476V, -477N, -478I, -479R, -480S, -481N, -482N, -483G, -484Y, -485T, -486C, -487I, -488T, -489I, -490A, -491I, -492N, -493E, -494S, -495R, -496N, -497I, -498E, -499L, -500L, -501K, -502M, -503L, -504L, -505C, -506H, -507K, -508P, -509T, -510L, -511D, -512C, -513V, -514I, -515D, -516S, -517L, -518S, -519E, -520V, -521S, -522N, -523I, -524V, -525D; OPG181: R249K"}}}]}]}]},{"name":"NODE_0000123","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G12169A","G44960A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]},"labels":{"clade":"B.1.17"}},"children":[{"name":"OP442552","node_attrs":{"div":558,"accession":"OP442552","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00085/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-13"},"strain_display":{"value":"USA/OP442552/2022-07-13"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G771-","T772-","G773-","A196789-","A196790-","T196791-"]}}},{"name":"OP392546","node_attrs":{"div":562,"accession":"OP392546","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"strain":{"value":"MpxV/human/USA/WA-UW-085171/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP392546/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A11836G","G69249A","C113363T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G171959A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG132":["D60N"]},"labels":{"aa":"OPG132: D60N"}}},{"name":"OP748959","node_attrs":{"div":559,"accession":"OP748959","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00273/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-14"},"strain_display":{"value":"USA/OP748959/2022-07-14"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T658-","A659-","T660-","A11160G"],"OPG023":["F581L"]},"labels":{"aa":"OPG023: F581L"}}},{"name":"OQ054244","node_attrs":{"div":558,"accession":"OQ054244","author":{"author":"Gigante,C.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y.","value":"Gigante,C.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"strain":{"value":"MPXV_USA_2022_CA0029"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ054244/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A173316-","T173317-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP890564","node_attrs":{"div":559,"accession":"OP890564","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00336/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-09"},"strain_display":{"value":"USA/OP890564/2022-11-09"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A39482T"],"OPG057":["H238Q"]},"labels":{"aa":"OPG057: H238Q"}}},{"name":"OP890547","node_attrs":{"div":558,"accession":"OP890547","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00289/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-04"},"strain_display":{"value":"USA/OP890547/2022-10-04"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000124","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A39395-","T39396-","T39397-","C85931T","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG057":["N267-"]},"labels":{"aa":"OPG057: N267-"}},"children":[{"name":"OQ547899","node_attrs":{"div":562,"accession":"OQ547899","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"country":{"value":"USA"},"institution":{"value":"CDPH, VRDL"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000184/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-10"},"strain_display":{"value":"USA/OQ547899/2023-01-10"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G71249A","G172895A","-179079A","-179080T","-179081A","G182189A"],"OPG090":["R24Q"]},"labels":{"aa":"OPG090: R24Q"}}},{"name":"OQ503816","node_attrs":{"div":559,"accession":"OQ503816","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.17"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00423/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-02"},"strain_display":{"value":"USA/OQ503816/2022-12-02"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179176A","-179177T","-179178A"]}}}]}]},{"name":"NODE_0000125","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","G149818A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G151362A"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG176":["D4N"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG176: D4N","clade":"B.1.15"}},"children":[{"name":"ON694335","node_attrs":{"div":558,"accession":"ON694335","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/Germany/2022/RKI018"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/ON694335/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-","A196614-"]}}},{"name":"OP324453","node_attrs":{"div":559,"accession":"OP324453","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"strain":{"value":"Monkeypox/PT0129/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-12"},"strain_display":{"value":"Portugal/OP324453/2022-07-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","C18133T","-196615A","-196616T"]}}},{"name":"OP484673","node_attrs":{"div":561,"accession":"OP484673","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/Germany/2022/RKI352"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP484673/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C21128T","G74187T","C151111T"],"OPG037":["E436K"],"OPG094":["Q136H"]},"labels":{"aa":"OPG037: E436K; OPG094: Q136H"}}},{"name":"OP764619","node_attrs":{"div":558,"accession":"OP764619","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/Germany/2022/RKI561"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OP764619/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000126","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C8385T","-11326A","-11327T","-11328C","-11329T","-11330A","-11331C","-11332G","-11333A","-11334T","-11335A","-11336T","-11337T","-11338A","-11339G","-11340A","-11341T","-11342A","-11343C","-11344T","-11345T","-11346C","-11347A","-11348C","-11349T","-11350C","-11351A","-11352A","-11353T","-11354G","-11355A","-11356A","-11357T","-11358C","-11359A","-11360A","-11361T","-11362C","-11363A","-11364C","-11365A","-11366C","-11367A","-11368A","-11369T","-11370C","-11371T","-11372A","-11373A","-11374T","-11375G","-11376T","-11377A","-11378G","-11379G","-11380T","-11381T","-11382T","-11383A","-11384T","-11385G","-11386A","-11387C","-11388A","-11389T","-11390A","-11391A","-11392T","-11393A","-11394G","-11395C","-11396A","-11397T","-11398T","-11399T","-11400T","-11401C","-11402A","-11403G","-11404C","-11405A","-11406G","-11407T","-11408T","-11409C","-11410A","-11411A","-11412T","-11413G","-11414T","-11415T","-11416T","-11417C","-11418T","-11419A","-11420G","-11421A","-11422T","-11423T","-11424C","-11425G","-11426T","-11427T","-11428G","-11429A","-11430T","-11431G","-11432G","-11433C","-11434A","-11435A","-11436T","-11437G","-11438G","-11439T","-11440T","-11441A","-11442T","-11443A","-11444C","-11445A","-11446T","-11447G","-11448T","-11449A","-11450T","-11451A","-11452T","-11453C","-11454C","-11455G","-11456T","-11457T","-11458A","-11459T","-11460T","-11461T","-11462G","-11463A","-11464T","-11465C","-11466T","-11467A","-11468A","-11469T","-11470G","-11471T","-11472T","-11473G","-11474A","-11475C","-11476A","-11477T","-11478C","-11479T","-11480G","-11481A","-11482A","-11483C","-11484C","-11485G","-11486G","-11487A","-11488T","-11489T","-11490C","-11491T","-11492A","-11493G","-11494C","-11495A","-11496G","-11497T","-11498A","-11499A","-11500A","-11501G","-11502A","-11503T","-11504A","-11505C","-11506T","-11507A","-11508G","-11509A","-11510G","-11511A","-11512T","-11513T","-11514G","-11515T","-11516T","-11517T","-11518A","-11519T","-11520T","-11521A","-11522T","-11523A","-11524T","-11525C","-11526T","-11527A","-11528A","-11529C","-11530A","-11531G","-11532C","-11533C","-11534T","-11535T","-11536G","-11537T","-11538G","-11539A","-11540A","-11541G","-11542A","-11543A","-11544G","-11545T","-11546G","-11547T","-11548T","-11549T","-11550C","-11551T","-11552C","-11553C","-11554T","-11555C","-11556G","-11557T","-11558T","-11559T","-11560G","-11561T","-11562C","-11563A","-11564A","-11565T","-11566C","-11567A","-11568T","-11569G","-11570T","-11571T","-11572A","-11573A","-11574T","-11575G","-11576T","-11577C","-11578T","-11579T","-11580T","-11581A","-11582A","-11583G","-11584A","-11585T","-11586A","-11587A","-11588G","-11589G","-11590T","-11591A","-11592G","-11593A","-11594C","-11595A","-11596A","-11597A","-11598T","-11599G","-11600T","-11601T","-11602T","-11603A","-11604T","-11605A","-11606G","-11607T","-11608A","-11609C","-11610T","-11611A","-11612A","-11613G","-11614A","-11615A","-11616T","-11617T","-11618G","-11619G","-11620G","-11621C","-11622A","-11623A","-11624A","-11625C","-11626A","-11627T","-11628A","-11629A","-11630G","-11631A","-11632C","-11633A","-11634T","-11635G","-11636T","-11637C","-11638A","-11639C","-11640A","-11641A","-11642A","-11643G","-11644A","-11645C","-11646C","-11647C","-11648T","-11649T","-11650T","-11651T","-11652T","-11653G","-11654T","-11655A","-11656T","-11657G","-11658T","-11659A","-11660T","-11661A","-11662A","-11663G","-11664T","-11665G","-11666T","-11667A","-11668G","-11669A","-11670A","-11671A","-11672T","-11673T","-11674A","-11675T","-11676A","-11677A","-11678C","-11679A","-11680T","-11681C","-11682C","-11683A","-11684T","-11685A","-11686G","-11687T","-11688T","-11689G","-11690G","-11691A","-11692T","-11693T","-11694C","-11695A","-11696C","-11697A","-11698T","-11699A","-11700G","-11701G","-11702T","-11703G","-11704T","-11705C","-11706C","-11707A","-11708A","-11709T","-11710C","-11711G","-11712G","-11713G","-11714A","-11715T","-11716C","-11717T","-11718C","-11719T","-11720C","-11721C","-11722A","-11723T","-11724C","-11725A","-11726T","-11727C","-11728G","-11729A","-11730G","-11731A","-11732T","-11733G","-11734A","-11735T","-11736T","-11737G","-11738A","-11739C","-11740G","-11741G","-11742C","-11743A","-11744T","-11745C","-11746T","-11747C","-11748C","-11749C","-11750C","-11751C","-11752T","-11753T","-11754C","-11755C","-11756T","-11757T","-11758T","-11759T","-11760T","-11761T","-11762A","-11763G","-11764T","-11765A","-11766G","-11767A","-11768T","-11769A","-11770T","-11771T","-11772T","-11773C","-11774A","-11775T","-11776C","-11777G","-11778T","-11779G","-11780T","-11781A","-11782A","-11783G","-11784A","-11785A","-11786T","-11787C","-11788A","-11789A","-11790T","-11791A","-11792T","-11793T","-11794A","-11795A","-11796T","-11797A","-11798T","-11799T","-11800T","-11801C","-11802T","-11803A","-11804A","-11805A","-11806G","-11807T","-11808A","-11809T","-11810C","-11811T","-11812G","-11813T","-11814G","-11815T","-11816A","-11817T","-11818A","-11819G","-11820C","-11821C","-11822T","-11823C","-11824T","-11825T","-11826T","-11827A","-11828T","-11829T","-11830T","-11831A","-11832C","-11833C","-11834A","-11835C","-11836A","-11837G","-11838C","-11839T","-11840C","-11841C","-11842A","-11843T","-11844A","-11845T","-11846T","-11847C","-11848C","-11849A","-11850A","-11851C","-11852A","-11853T","-11854G","-11855C","-11856A","-11857T","-11858T","-11859C","-11860C","-11861A","-11862C","-11863T","-11864A","-11865G","-11866A","-11867G","-11868G","-11869G","-11870A","-11871T","-11872A","-11873T","-11874C","-11875G","-11876A","-11877T","-11878A","-11879T","-11880C","-11881G","-11882C","-11883C","-11884G","-11885A","-11886A","-11887T","-11888G","-11889T","-11890C","-11891A","-11892T","-11893A","-11894T","-11895A","-11896C","-11897T","-11898C","-11899A","-11900A","-11901T","-11902T","-11903A","-11904G","-11905T","-11906A","-11907T","-11908A","-11909T","-11910G","-11911T","-11912T","-11913G","-11914G","-11915A","-11916G","-11917G","-11918A","-11919C","-11920A","-11921T","-11922C","-11923C","-11924G","-11925A","-11926G","-11927T","-11928T","-11929C","-11930A","-11931T","-11932T","-11933G","-11934T","-11935T","-11936T","-11937T","-11938C","-11939A","-11940A","-11941T","-11942A","-11943T","-11944C","-11945A","-11946A","-11947A","-11948G","-11949A","-11950G","-11951A","-11952T","-11953G","-11954G","-11955T","-11956T","-11957T","-11958C","-11959C","-11960T","-11961T","-11962A","-11963T","-11964C","-11965A","-11966T","-11967T","-11968T","-11969C","-11970T","-11971C","-11972C","-11973A","-11974T","-11975A","-11976G","-11977T","-11978G","-11979G","-11980T","-11981A","-11982C","-11983A","-11984A","-11985T","-11986A","-11987C","-11988T","-11989A","-11990C","-11991A","-11992C","-11993A","-11994T","-11995T","-11996A","-11997T","-11998T","-11999C","-12000C","-12001G","-12002T","-12003A","-12004C","-12005G","-12006G","-12007C","-12008T","-12009T","-12010T","-12011C","-12012C","-12013A","-12014T","-12015T","-12016C","-12017T","-12018C","-12019C","-12020A","-12021A","-12022A","-12023A","-12024A","-12025C","-12026A","-12027A","-12028T","-12029T","-12030T","-12031T","-12032A","-12033C","-12034C","-12035A","-12036A","-12037A","-12038T","-12039C","-12040T","-12041A","-12042A","-12043A","-12044T","-12045C","-12046T","-12047A","-12048C","-12049A","-12050T","-12051C","-12052T","-12053T","-12054T","-12055A","-12056T","-12057T","-12058G","-12059T","-12060A","-12061T","-12062C","-12063T","-12064A","-12065T","-12066A","-12067A","-12068T","-12069C","-12070A","-12071C","-12072T","-12073A","-12074T","-12075T","-12076T","-12077A","-12078G","-12079A","-12080T","-12081A","-12082A","-12083T","-12084C","-12085A","-12086G","-12087C","-12088C","-12089A","-12090T","-12091A","-12092A","-12093T","-12094T","-12095C","-12096C","-12097T","-12098C","-12099G","-12100A","-12101G","-12102T","-12103G","-12104C","-12105A","-12106A","-12107C","-12108A","-12109T","-12110G","-12111T","-12112T","-12113A","-12114G","-12115A","-12116T","-12117C","-12118G","-12119T","-12120C","-12121T","-12122A","-12123T","-12124A","-12125T","-12126A","-12127T","-12128G","-12129A","-12130A","-12131T","-12132A","-12133A","-12134G","-12135C","-12136C","-12137G","-12138T","-12139G","-12140T","-12141T","-12142A","-12143T","-12144C","-12145T","-12146A","-12147T","-12148T","-12149C","-12150C","-12151T","-12152T","-12153T","-12154C","-12155A","-12156T","-12157T","-12158A","-12159A","-12160C","-12161A","-12162A","-12163T","-12164T","-12165T","-12166A","-12167A","-12168C","-12169G","-12170A","-12171T","-12172G","-12173T","-12174C","-12175T","-12176A","-12177T","-12178A","-12179T","-12180C","-12181T","-12182A","-12183T","-12184A","-12185T","-12186G","-12187A","-12188G","-12189A","-12190T","-12191G","-12192A","-12193C","-12194T","-12195T","-12196A","-12197A","-12198T","-12199A","-12200T","-12201A","-12202A","-12203T","-12204A","-12205T","-12206T","-12207G","-12208A","-12209A","-12210G","-12211A","-12212G","-12213C","-12214T","-12215G","-12216T","-12217A","-12218C","-12219A","-12220A","-12221T","-12222A","-12223G","-12224T","-12225T","-12226T","-12227T","-12228T","-12229A","-12230T","-12231C","-12232T","-12233A","-12234T","-12235A","-12236G","-12237A","-12238A","G40242A","C40335T","G139582A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG023":["-222S","-223I","-224D","-225K","-226N","-227Y","-228C","-229T","-230A","-231L","-232Q","-233Y","-234Y","-235I","-236K","-237S","-238S","-239H","-240I","-241D","-242I","-243D","-244I","-245V","-246K","-247L","-248L","-249M","-250K","-251G","-252I","-253D","-254N","-255T","-256A","-257Y","-258S","-259Y","-260I","-261D","-262D","-263L","-264T","-265C","-266C","-267T","-268R","-269G","-270I","-271M","-272A","-273D","-274Y","-275L","-276N","-277S","-278D","-279Y","-280R","-281Y","-282N","-283K","-284D","-285V","-286D","-287L","-288D","-289L","-290V","-291K","-292L","-293F","-294L","-295E","-296N","-297G","-298K","-299P","-300Y","-301G","-302I","-303M","-304C","-305S","-306I","-307V","-308P","-309L","-310W","-311R","-312N","-313D","-314K","-315E","-316T","-317I","-318S","-319L","-320I","-321L","-322K","-323T","-324M","-325N","-326S","-327D","-328V","-329L","-330Q","-331H","-332I","-333L","-334I","-335E","-336Y","-337M","-338T","-339F","-340G","-341D","-342I","-343D","-344I","-345P","-346L","-347V","-348E","-349C","-350M","-351L","-352E","-353Y","-354G","-355A","-356V","-357V","-358N","-359K","-360E","-361A","-362I","-363H","-364R","-365Y","-366F","-367R","-368N","-369I","-370N","-371I","-372D","-373S","-374Y","-375T","-376M","-377K","-378Y","-379L","-380L","-381K","-382K","-383E","-384G","-385G","-386D","-387A","-388V","-389N","-390H","-391L","-392D","-393D","-394G","-395E","-396I","-397P","-398I","-399G","-400H","-401L","-402C","-403E","-404S","-405N","-406Y","-407G","-408C","-409Y","-410N","-411F","-412Y","-413T","-414Y","-415T","-416Y","-417K","-418K","-419G","-420L","-421C","-422D","-423M","-424S","-425Y","-426V","-427C","-428P","-429I","-430L","-431S","-432T","-433I","-434N","-435I","-436C","-437L","-438P","-439Y","-440L","-441K","-442D","-443I","-444N","-445M","-446I","-447D","-448K","-449R","-450G","-451E","-452T","-453L","-454L","-455H","-456K","-457A","-458V","-459R","-460Y","-461N","-462K","-463Q","-464S","-465L","-466V","-467S","-468L","-469L","-470L","-471E","-472S","-473G","-474S","-475D","-476V","-477N","-478I","-479R","-480S","-481N","-482N","-483G","-484Y","-485T","-486C","-487I","-488T","-489I","-490A","-491I","-492N","-493E","-494S","-495R","-496N","-497I","-498E","-499L","-500L","-501K","-502M","-503L","-504L","-505C","-506H","-507K","-508P","-509T","-510L","-511D","-512C","-513V","-514I","-515D","-516S","-517L","-518S","-519E","-520V","-521S","-522N","-523I","-524V","-525D"],"OPG058":["E34K"]},"labels":{"aa":"OPG023: -222S, -223I, -224D, -225K, -226N, -227Y, -228C, -229T, -230A, -231L, -232Q, -233Y, -234Y, -235I, -236K, -237S, -238S, -239H, -240I, -241D, -242I, -243D, -244I, -245V, -246K, -247L, -248L, -249M, -250K, -251G, -252I, -253D, -254N, -255T, -256A, -257Y, -258S, -259Y, -260I, -261D, -262D, -263L, -264T, -265C, -266C, -267T, -268R, -269G, -270I, -271M, -272A, -273D, -274Y, -275L, -276N, -277S, -278D, -279Y, -280R, -281Y, -282N, -283K, -284D, -285V, -286D, -287L, -288D, -289L, -290V, -291K, -292L, -293F, -294L, -295E, -296N, -297G, -298K, -299P, -300Y, -301G, -302I, -303M, -304C, -305S, -306I, -307V, -308P, -309L, -310W, -311R, -312N, -313D, -314K, -315E, -316T, -317I, -318S, -319L, -320I, -321L, -322K, -323T, -324M, -325N, -326S, -327D, -328V, -329L, -330Q, -331H, -332I, -333L, -334I, -335E, -336Y, -337M, -338T, -339F, -340G, -341D, -342I, -343D, -344I, -345P, -346L, -347V, -348E, -349C, -350M, -351L, -352E, -353Y, -354G, -355A, -356V, -357V, -358N, -359K, -360E, -361A, -362I, -363H, -364R, -365Y, -366F, -367R, -368N, -369I, -370N, -371I, -372D, -373S, -374Y, -375T, -376M, -377K, -378Y, -379L, -380L, -381K, -382K, -383E, -384G, -385G, -386D, -387A, -388V, -389N, -390H, -391L, -392D, -393D, -394G, -395E, -396I, -397P, -398I, -399G, -400H, -401L, -402C, -403E, -404S, -405N, -406Y, -407G, -408C, -409Y, -410N, -411F, -412Y, -413T, -414Y, -415T, -416Y, -417K, -418K, -419G, -420L, -421C, -422D, -423M, -424S, -425Y, -426V, -427C, -428P, -429I, -430L, -431S, -432T, -433I, -434N, -435I, -436C, -437L, -438P, -439Y, -440L, -441K, -442D, -443I, -444N, -445M, -446I, -447D, -448K, -449R, -450G, -451E, -452T, -453L, -454L, -455H, -456K, -457A, -458V, -459R, -460Y, -461N, -462K, -463Q, -464S, -465L, -466V, -467S, -468L, -469L, -470L, -471E, -472S, -473G, -474S, -475D, -476V, -477N, -478I, -479R, -480S, -481N, -482N, -483G, -484Y, -485T, -486C, -487I, -488T, -489I, -490A, -491I, -492N, -493E, -494S, -495R, -496N, -497I, -498E, -499L, -500L, -501K, -502M, -503L, -504L, -505C, -506H, -507K, -508P, -509T, -510L, -511D, -512C, -513V, -514I, -515D, -516S, -517L, -518S, -519E, -520V, -521S, -522N, -523I, -524V, -525D; OPG058: E34K"}},"children":[{"name":"OP642402","node_attrs":{"div":564,"accession":"OP642402","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"strain":{"value":"ANT-LDSP-ANT-MPX-24957C"},"date":{"value":"2022-09-12"},"strain_display":{"value":"Colombia/OP642402/2022-09-12"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G125388A","G126763A","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-"],"OPG145":["R481H"],"OPG148":["E260K"]},"labels":{"aa":"OPG145: R481H; OPG148: E260K"}}},{"name":"NODE_0000127","node_attrs":{"div":563,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C127609T"]}},"children":[{"name":"OP431400","node_attrs":{"div":566,"accession":"OP431400","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"strain":{"value":"ANT-LDSP-ANT-MPX-22751-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-17"},"strain_display":{"value":"Colombia/OP431400/2022-08-17"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G47482A","C60062T","G125388A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG080":["E653K"],"OPG145":["R481H"]},"labels":{"aa":"OPG080: E653K; OPG145: R481H"}}},{"name":"OP819950","node_attrs":{"div":565,"accession":"OP819950","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"strain":{"value":"MET_INS_MPX_0956_C"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-12"},"strain_display":{"value":"Colombia/OP819950/2022-10-12"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G144284A","C171808T","G196973-","A196974-","A196975-"],"OPG165":["D257N"],"OPG199":["S274L"]},"labels":{"aa":"OPG165: D257N; OPG199: S274L"}}},{"name":"OR035721","node_attrs":{"div":565,"accession":"OR035721","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/UZ_REGA_115"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035721/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C21324T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G180556A","T196712-","A196713-","T196714-"]}}},{"name":"OR086972","node_attrs":{"div":568,"accession":"OR086972","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/UZ_REGA_163/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR086972/2022-07-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G31180A","C142626T","G158549A","G159341A","C170750T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG163":["S142L"],"OPG185":["G142E"],"OPG198":["A238V"]},"labels":{"aa":"OPG163: S142L; OPG185: G142E; OPG198: A238V"}}}]}]}]},{"name":"NODE_0000128","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G175093A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179194A","-179195T","-179199C","-179208C","-179217C","-179226C","-179235C"],"OPG204":["D188N"]},"labels":{"aa":"OPG204: D188N","clade":"B.1.13"}},"children":[{"name":"OP536663","node_attrs":{"div":559,"accession":"OP536663","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"country":{"value":"USA"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV-USA-IL-IDPH-002"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-04"},"strain_display":{"value":"USA/OP536663/2022-08-04"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G119424A","G125452A","-179193T","-179196A","-179197T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG136":["S55L"],"OPG146":["S63L"]},"labels":{"aa":"OPG136: S55L; OPG146: S63L"}}},{"name":"NODE_0000129","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G22814A","G55162A","G137128A","G167910A","-179193T","-179196A","-179197T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG038":["H116Y"],"OPG074":["S655L"],"OPG193":["E193K"]},"labels":{"aa":"OPG038: H116Y; OPG074: S655L; OPG193: E193K"}},"children":[{"name":"OP536673","node_attrs":{"div":561,"accession":"OP536673","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"country":{"value":"USA"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV-USA-IL-IDPH-012"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"strain_display":{"value":"USA/OP536673/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-196615A","-196616A","-196617A"]}}},{"name":"NODE_0000130","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C118921T","A173316-","T173317-"],"OPG136":["D223N"]},"labels":{"aa":"OPG136: D223N"}},"children":[{"name":"OQ320456","node_attrs":{"div":562,"accession":"OQ320456","author":{"author":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y.","value":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV_USA_2022_KS0004"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ320456/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"OQ721921","node_attrs":{"div":563,"accession":"OQ721921","author":{"author":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y.","value":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV_USA_2022_KS0005"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721921/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C110297T","A173314-","T173315-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-"]}}}]}]},{"name":"NODE_0000131","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C132520T"]}},"children":[{"name":"OP257254","node_attrs":{"div":558,"accession":"OP257254","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"MpxV/human/USA/OH-UW-073812/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP257254/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179193T","-179196A","-179197T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR160418","node_attrs":{"div":565,"accession":"OR160418","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"country":{"value":"USA"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-052-0034/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-05-10"},"strain_display":{"value":"USA/OR160418/2023-05-10"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C27520T","G58883A","G99832A","G102186A","G129583A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G171410A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","A179194-","T179195-","C179199-","C179208-","C179217-","C179226-","C179235-","C182950T"],"OPG043":["A146T"],"OPG118":["D463N"],"OPG121":["E133K"],"OPG210":["S532L"]},"labels":{"aa":"OPG043: A146T; OPG118: D463N; OPG121: E133K; OPG210: S532L"}}},{"name":"NODE_0000132","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G165086A"]}},"children":[{"name":"OP536701","node_attrs":{"div":560,"accession":"OP536701","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"country":{"value":"USA"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV-USA-IL-IDPH-040"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-22"},"strain_display":{"value":"USA/OP536701/2022-06-22"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C169529T","-179193T","-179196A","-179197T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"OP820455","node_attrs":{"div":562,"accession":"OP820455","author":{"author":"Barbian,H.,Green,S.,Kunstman,K.,Araujo Perez,F.,Bobrovska,S.,Hayden,M.,Moore,N.","value":"Barbian,H.,Green,S.,Kunstman,K.,Araujo Perez,F.,Bobrovska,S.,Hayden,M.,Moore,N."},"country":{"value":"USA"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"hMpxV/Human/USA/IL-RIPHL-MPXV_10006/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-08"},"strain_display":{"value":"USA/OP820455/2022-08-08"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","C85055T","G142550A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G165904A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","A179194-","T179195-","C179199-","C179208-","C179217-","C179226-","C179235-","A196614-"],"OPG163":["D117N"]},"labels":{"aa":"OPG163: D117N"}}}]},{"name":"NODE_0000133","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C21383T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179199-","C179208-","C179217-","C179226-","C179235-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG037":["G351S"]},"labels":{"aa":"OPG037: G351S"}},"children":[{"name":"OQ319139","node_attrs":{"div":561,"accession":"OQ319139","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV/Germany/2022/ON/RKI681"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OQ319139/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C24584T","G27462A","G150551-","A150569-","T150570-","A150571-","T150572-","G150573-","A150574-","T150575-","G150576-","A152676-","T152686-","A179194-","T179195-"],"OPG040":["D299N"],"OPG043":["S165L"]},"labels":{"aa":"OPG040: D299N; OPG043: S165L"}}},{"name":"OQ773520","node_attrs":{"div":562,"accession":"OQ773520","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV/Germany/2022/ON/RKI901"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773520/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G85431A","C146446T","C147140T","C179265-","A179266-","T179267-"],"OPG106":["S23F"],"OPG170":["M111I"]},"labels":{"aa":"OPG106: S23F; OPG170: M111I"}}}]}]}]},{"name":"NODE_0000134","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G111029A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]},"labels":{"clade":"B.1.6"}},"children":[{"name":"OP320549","node_attrs":{"div":557,"accession":"OP320549","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"country":{"value":"Peru"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"LIM-INS-010"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-02"},"strain_display":{"value":"Peru/OP320549/2022-07-02"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{}}},{"name":"OP289783","node_attrs":{"div":557,"accession":"OP289783","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Mestanza,O.,Lope,P.,Nunez,A.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Mestanza,O.,Lope,P.,Nunez,A."},"country":{"value":"Peru"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"LIM-INS-003"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-27"},"strain_display":{"value":"Peru/OP289783/2022-06-27"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{}}},{"name":"OP289782","node_attrs":{"div":557,"accession":"OP289782","author":{"author":"Silva,I.,Jimenez,V.,Hurtado,V.,Barcena,L.","value":"Silva,I.,Jimenez,V.,Hurtado,V.,Barcena,L."},"country":{"value":"Peru"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"LIM-INS-001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-25"},"strain_display":{"value":"Peru/OP289782/2022-06-25"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-196615A","-196616A","-196617A"]}}},{"name":"OP431402","node_attrs":{"div":558,"accession":"OP431402","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"ANT-LDSP-ANT-MPX-22752-O"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-18"},"strain_display":{"value":"Colombia/OP431402/2022-08-18"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G15814A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP536765","node_attrs":{"div":559,"accession":"OP536765","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"9000387"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP536765/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G59112A","C87978T"]}}},{"name":"OQ197863","node_attrs":{"div":558,"accession":"OQ197863","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Rosales,A.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Rosales,A.,Mercado-Reyes,M.M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"DC_INS_MPX-1122-H"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-22"},"strain_display":{"value":"Colombia/OQ197863/2022-10-22"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C151204T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"]}}},{"name":"OQ348868","node_attrs":{"div":559,"accession":"OQ348868","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"country":{"value":"USA"},"institution":{"value":"CDPH, VRDL"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000120/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-20"},"strain_display":{"value":"USA/OQ348868/2022-09-20"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","G150364A","C166930T"],"OPG176":["E186K"],"OPG192":["S67L"]},"labels":{"aa":"OPG176: E186K; OPG192: S67L"}}},{"name":"OQ503831","node_attrs":{"div":561,"accession":"OQ503831","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00408/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-11"},"strain_display":{"value":"USA/OQ503831/2023-01-11"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","G10945A","G39515A","C44627T","G56276A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A196614-"],"OPG064":["M424I"]},"labels":{"aa":"OPG064: M424I"}}},{"name":"NODE_0000135","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G132863A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A181356-","T181357-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","A181366-","A181368-","A181369-","A181370-","T181371-","T181372-"]}},"children":[{"name":"OP642401","node_attrs":{"div":558,"accession":"OP642401","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"ANT-LDSP-ANT-MPX-24947E"},"date":{"value":"2022-09-12"},"strain_display":{"value":"Colombia/OP642401/2022-09-12"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C181355-","G181358-","C181365-","G181367-"]}}},{"name":"OQ696099","node_attrs":{"div":561,"accession":"OQ696099","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"ANT-LDSP-ANT-MPX-30518C"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-09"},"strain_display":{"value":"Colombia/OQ696099/2022-11-09"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G63811A","G167862A","C170130T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","-181356A","-181357T","-181359A","-181360A","-181361T","-181362T","-181363T","-181364T","-181366A","-181368A","-181369A","-181370A","-181371T","-181372T"],"OPG193":["D177N"]},"labels":{"aa":"OPG193: D177N"}}}]},{"name":"NODE_0000136","node_attrs":{"div":563,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C14098T","C84063T","G142493A","G151324A","C170573T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","C187332T"],"OPG163":["D98N"],"OPG198":["S179L"]},"labels":{"aa":"OPG163: D98N; OPG198: S179L"}},"children":[{"name":"OQ503815","node_attrs":{"div":565,"accession":"OQ503815","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00422/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-03"},"strain_display":{"value":"USA/OQ503815/2022-12-03"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G97749A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","G188726A"]}}},{"name":"OR499960","node_attrs":{"div":568,"accession":"OR499960","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.6"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00503/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-15"},"strain_display":{"value":"USA/OR499960/2023-03-15"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G6746A","C39266T","C63819T","G106927A","G138862A","G169213A","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG083":["V300I"],"OPG125":["T243M"],"OPG156":["S183F"]},"labels":{"aa":"OPG083: V300I; OPG125: T243M; OPG156: S183F"}}}]}]},{"name":"NODE_0000137","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-","C148268T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"ON755039","node_attrs":{"div":557,"accession":"ON755039","author":{"author":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O.","value":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O."},"country":{"value":"France"},"institution":{"value":"IRBA, D.DNRBC/D.2MI/U.BACT"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_IRBA22-11"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-19"},"strain_display":{"value":"France/ON755039/2022-05-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T133097-","T133098-","T133099-","T133100-","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"NODE_0000138","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G9963A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T"],"OPG021":["R126K"]},"labels":{"aa":"OPG021: R126K","clade":"B.1.19"}},"children":[{"name":"OP270026","node_attrs":{"div":558,"accession":"OP270026","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"MpxV/human/CAN/UN-NML-4017/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"strain_display":{"value":"Canada/OP270026/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-133101T","-133102T","-196615A","-196616A","-196617A"]}}},{"name":"OP838893","node_attrs":{"div":558,"accession":"OP838893","author":{"author":"Viscardi,M.,Cozzolino,L.,De Martinis,C.,Cardillo,L.,Fusco,G.","value":"Viscardi,M.,Cozzolino,L.,De Martinis,C.,Cardillo,L.,Fusco,G."},"country":{"value":"Italy"},"institution":{"value":"Istituto Zooprofilattico Sperimentale del Mezzogiorno, Hanimal Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"ID6821"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-21"},"strain_display":{"value":"Italy/OP838893/2022-06-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","T133100-","C133103-","G133104-","A133105-","A133106-","T133107-","T133108-","C133109-","A133110-","C133111-","G133112-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A157678-","A157679-","A157680-","A157681-","T157682-","T157683-","T157684-","T157685-","A157686-","A157687-","G157688-","C157689-","G157690-","A157691-","T157692-","G157693-","A157694-","T157695-","A157696-","T163214-","C163215-","T163216-","T163217-","A163218-","T163219-","A163220-","T163221-","A163417-","A163418-","T163419-","T163420-","C163421-","T163422-","T163423-","C163424-","C163425-","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","G174537-","A174538-","T174539-","G174540-","A174541-","A174542-","A180482-","T180483-","T180484-","A180485-","A180486-","A180487-","A180488-","A180489-","A181114-","T181115-","T181116-","C181117-","C181118-","T181119-","T181120-","A181121-","T181122-","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-"],"OPG159":["N124-","Y125-","N126-"],"OPG189":["N29-","S30-","S31-"]},"labels":{"aa":"OPG159: N124-, Y125-, N126-; OPG189: N29-, S30-, S31-"}}},{"name":"OR035726","node_attrs":{"div":560,"accession":"OR035726","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV/UZ_REGA_120"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035726/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C22739T","-133101T","-133102T","G133104A","G133231A","T137560-","G164487A"],"OPG038":["E141K"]},"labels":{"aa":"OPG038: E141K"}}},{"name":"OR086965","node_attrs":{"div":563,"accession":"OR086965","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV/UZ_REGA_156/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR086965/2022-07-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C71016T","G77415A","G133319A","C176069T","G181309A"],"OPG089":["S384L"]},"labels":{"aa":"OPG089: S384L"}}},{"name":"NODE_0000139","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-133101T","-133102T","G150003A","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"]}},"children":[{"name":"OP382486","node_attrs":{"div":562,"accession":"OP382486","author":{"author":"Colson,P.","value":"Colson,P."},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"hMPXV-IHU00009"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-07"},"strain_display":{"value":"France/OP382486/2022-07-07"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C38483T","C164272T","G175971A"],"OPG189":["R314C"],"OPG205":["E106K"]},"labels":{"aa":"OPG189: R314C; OPG205: E106K"}}},{"name":"OQ172215","node_attrs":{"div":563,"accession":"OQ172215","author":{"author":"Zeggagh,J.,Ferraris,O.,Salmona,M.,Tarantola,A.,Molina,J.M.,Delaugerre,C.","value":"Zeggagh,J.,Ferraris,O.,Salmona,M.,Tarantola,A.,Molina,J.M.,Delaugerre,C."},"country":{"value":"France"},"institution":{"value":"Hopital Saint Louis, Paris"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV-1047"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-07"},"strain_display":{"value":"France/OQ172215/2022-06-07"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A2591G","A31053G","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133171-","C133172-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T133639-","A150635-","A152676-","T152686-","T155897A","C173533A","A179077T","A179079T","A179081T","C179082T","A179083T","A179086T","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","T194619C","T194627G"],"OPG002":["F54S"],"OPG002_dup":["F54S","C57G"],"OPG047":["C48R"]},"labels":{"aa":"OPG002: F54S; OPG002_dup: F54S, C57G; OPG047: C48R"}}},{"name":"OQ427121","node_attrs":{"div":560,"accession":"OQ427121","author":{"author":"Gigante,C.,Cogswell,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Grenz,L.,Li,Y.","value":"Gigante,C.,Cogswell,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Grenz,L.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV_USA_2022_OR0008"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OQ427121/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","C150140T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"],"OPG176":["S111L"]},"labels":{"aa":"OPG176: S111L"}}},{"name":"OR095050","node_attrs":{"div":562,"accession":"OR095050","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV/UZ_REGA_232/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-12"},"strain_display":{"value":"Belgium/OR095050/2022-08-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G57033A","G77415A","G83609A","T133101-","T133102-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C196750-","T196751-","A196752-"]}}},{"name":"NODE_0000140","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A169944T","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C185326T","-196615A"],"OPG197":["E92V"],"OPG210":["S1324L"]},"labels":{"aa":"OPG197: E92V; OPG210: S1324L"}},"children":[{"name":"OP555643","node_attrs":{"div":562,"accession":"OP555643","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"Monkeypox/PT0572/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-05"},"strain_display":{"value":"Portugal/OP555643/2022-09-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","C55057T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-"],"OPG073":["E29K"]},"labels":{"aa":"OPG073: E29K"}}},{"name":"OQ159056","node_attrs":{"div":565,"accession":"OQ159056","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV/Germany/2022/ON/RKI661"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OQ159056/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C2652T","G9584A","C87741T","G98995A","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG002":["D34N"],"OPG118":["E184K"]},"labels":{"aa":"OPG002: D34N; OPG118: E184K"}}}]},{"name":"NODE_0000141","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C74417T"],"OPG094":["S213L"]},"labels":{"aa":"OPG094: S213L"}},"children":[{"name":"OP205108","node_attrs":{"div":560,"accession":"OP205108","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV_UK_2022_9000145"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-16"},"strain_display":{"value":"United Kingdom/OP205108/2022-06-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OP413717","node_attrs":{"div":560,"accession":"OP413717","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"9000353"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP413717/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OP555533","node_attrs":{"div":561,"accession":"OP555533","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"Monkeypox/PT0452/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-04"},"strain_display":{"value":"Portugal/OP555533/2022-08-04"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-609T","G610-","T611-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C177833T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP536782","node_attrs":{"div":560,"accession":"OP536782","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.19"},"strain":{"value":"9000406"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536782/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}}]}]}]}]},{"name":"NODE_0000142","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","C187620T"]}},"children":[{"name":"OR464209","node_attrs":{"div":560,"accession":"OR464209","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_USA_2022_TX0056"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR464209/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","C1015T","G63034A","G103173A","C166214T","G196195A","A196614-"],"OPG082":["S140L"]},"labels":{"aa":"OPG082: S140L"}}},{"name":"NODE_0000143","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G53326A","C164385T","-196615A"]},"labels":{"clade":"B.1.20"}},"children":[{"name":"OQ320441","node_attrs":{"div":559,"accession":"OQ320441","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV_USA_2022_TX0040"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ320441/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"]}}},{"name":"OQ427125","node_attrs":{"div":561,"accession":"OQ427125","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV_USA_2022_TX0044"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ427125/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G48645A","G130027A"],"OPG068":["E149K"]},"labels":{"aa":"OPG068: E149K"}}},{"name":"OQ721939","node_attrs":{"div":561,"accession":"OQ721939","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV_USA_2022_TN0016"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721939/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C76839T","G89916A","T133101-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG097":["D13N"]},"labels":{"aa":"OPG097: D13N"}}},{"name":"OR464211","node_attrs":{"div":564,"accession":"OR464211","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV_USA_2022_TX0058"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR464211/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C9389T","C70539T","C71059T","C118247T","G118657A","A136552-","T136553-","C136554-"],"OPG089":["A225V"],"OPG136":["P311S"],"OPG153":["D385-"]},"labels":{"aa":"OPG089: A225V; OPG136: P311S; OPG153: D385-"}}},{"name":"NODE_0000144","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T602-","T603-","T604-","T605-","T606-","T607-","-133102T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177398A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","A196610-","A196611-","A196612-","A196613-","A196614-","A196615-"]}},"children":[{"name":"OQ427126","node_attrs":{"div":562,"accession":"OQ427126","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV_USA_2022_TX0045"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"USA/OQ427126/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G36027A","C72221T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A"],"OPG055":["R353C"],"OPG092":["E243K"]},"labels":{"aa":"OPG055: R353C; OPG092: E243K"}}},{"name":"OQ918695","node_attrs":{"div":560,"accession":"OQ918695","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00484/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-07"},"strain_display":{"value":"USA/OQ918695/2023-02-07"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ644783","node_attrs":{"div":560,"accession":"OQ644783","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00477/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-17"},"strain_display":{"value":"USA/OQ644783/2023-01-17"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T179179-","A179180-"]}}},{"name":"NODE_0000145","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C177899T","T179179-","A179180-"]}},"children":[{"name":"OR499995","node_attrs":{"div":568,"accession":"OR499995","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00539/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-07-23"},"strain_display":{"value":"USA/OR499995/2023-07-23"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C15718T","C22349T","C23353T","C83753T","G98119A","C113363T","G119341A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG037":["E29K"],"OPG039":["D256N"],"OPG117":["E691K"],"OPG132":["D60N"],"OPG136":["R83C"]},"labels":{"aa":"OPG037: E29K; OPG039: D256N; OPG117: E691K; OPG132: D60N; OPG136: R83C"}}},{"name":"NODE_0000146","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A662-","G146690A","T196633-","T196635-"],"OPG170":["S30F"]},"labels":{"aa":"OPG170: S30F"}},"children":[{"name":"OR665164","node_attrs":{"div":565,"accession":"OR665164","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MpxV/human/USA/WA-UW-098659/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-09-XX"},"strain_display":{"value":"USA/OR665164/2023-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-602T","-662A","G141131A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C159608T","G163900-","A163901-","A163902-","T163903-","C163904-","A163905-","G168964A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A192393C","G192396A","A192402G","-196610A","-196633T","-196635T"],"OPG185":["S231F"],"OPG189":["E190-","S191-"]},"labels":{"aa":"OPG185: S231F; OPG189: E190-, S191-"}}},{"name":"OR499949","node_attrs":{"div":562,"accession":"OR499949","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00492/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-30"},"strain_display":{"value":"USA/OR499949/2023-03-30"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A196713-","T196714-","A196715-"]}}},{"name":"OR499956","node_attrs":{"div":562,"accession":"OR499956","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00499/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-04-30"},"strain_display":{"value":"USA/OR499956/2023-04-30"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C661-","C663-","C196634-"]}}}]},{"name":"NODE_0000147","node_attrs":{"div":563,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C20453T","T164946C"]}},"children":[{"name":"OR449306","node_attrs":{"div":563,"accession":"OR449306","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Germany/2023/RKI1020"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-07-XX"},"strain_display":{"value":"Germany/OR449306/2023-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-602T","-603T","-604T","-605T","-606T","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"]}}},{"name":"OR421480","node_attrs":{"div":563,"accession":"OR421480","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"country":{"value":"USA"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0023/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-05-07"},"strain_display":{"value":"USA/OR421480/2023-05-07"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"OR725698","node_attrs":{"div":567,"accession":"OR725698","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"country":{"value":"USA"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"hMpxV/USA/IL-RIPHL-052-0100/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-08-22"},"strain_display":{"value":"USA/OR725698/2023-08-22"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-604T","-605T","-606T","C105798T","G148126A","C174050T","C180618T"],"OPG209":["S34L"]},"labels":{"aa":"OPG209: S34L"}}},{"name":"OR500003","node_attrs":{"div":565,"accession":"OR500003","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00547/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-06-12"},"strain_display":{"value":"USA/OR500003/2023-06-12"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C2313T","G51378A","A140155T","A140156G"],"OPG002":["D147N"],"OPG159":["N130C"]},"labels":{"aa":"OPG002: D147N; OPG159: N130C"}}}]}]}]}]}]},{"name":"NODE_0000148","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C18133T","G67611A","G130231A","G159277A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T"],"OPG185":["E121K"]},"labels":{"aa":"OPG185: E121K","clade":"B.1.11"}},"children":[{"name":"OP169336","node_attrs":{"div":560,"accession":"OP169336","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MpxV/human/USA/WA-UW-070499/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OP169336/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OP440607","node_attrs":{"div":565,"accession":"OP440607","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00065/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"USA/OP440607/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G2143-","C2144-","T2145-","G2146-","A2147-","G2148-","A2149-","C2150-","C2151-","G2152-","G2153-","T2154-","A2155-","G2156-","T2157-","G2158-","G2159-","T2160-","C2161-","G2162-","T2163-","C2164-","C2165-","G2166-","A2167-","G2168-","T2169-","A2170-","C2171-","A2172-","C2173-","G2174-","A2175-","T2176-","G2177-","T2178-","G2179-","T2180-","C2181-","G2182-","T2183-","T2184-","G2185-","A2186-","C2187-","T2188-","G2189-","G2190-","A2191-","T2192-","A2193-","C2194-","A2195-","G2196-","G2197-","T2198-","T2199-","A2200-","A2201-","T2202-","T2203-","T2204-","C2205-","C2206-","A2207-","C2208-","A2209-","T2210-","C2211-","G2212-","A2213-","T2214-","A2215-","T2216-","A2217-","G2218-","T2219-","T2220-","A2221-","A2222-","A2223-","T2224-","G2225-","T2226-","A2227-","T2228-","T2229-","G2230-","C2231-","T2232-","G2233-","G2234-","T2235-","T2236-","A2237-","C2238-","G2239-","A2240-","C2241-","G2242-","G2243-","G2244-","T2245-","T2246-","C2247-","G2248-","C2249-","A2250-","T2251-","T2252-","T2253-","A2254-","T2255-","C2256-","T2257-","G2258-","T2259-","G2260-","G2261-","A2262-","A2263-","G2264-","A2265-","G2266-","A2267-","C2268-","G2269-","G2270-","T2271-","G2272-","T2273-","G2274-","A2275-","G2276-","A2277-","A2278-","T2279-","A2280-","T2281-","G2282-","T2283-","T2284-","C2285-","C2286-","G2287-","G2288-","G2289-","A2290-","C2291-","C2292-","A2293-","C2294-","A2295-","C2296-","G2297-","G2298-","A2299-","G2300-","A2301-","A2302-","C2303-","A2304-","G2305-","A2306-","T2307-","G2308-","A2309-","C2310-","G2311-","T2312-","C2313-","T2314-","C2315-","C2316-","G2317-","G2318-","T2319-","A2320-","G2321-","A2322-","C2323-","G2324-","T2325-","G2326-","T2327-","A2328-","T2329-","C2330-","C2331-","G2332-","G2333-","A2334-","T2335-","A2336-","C2337-","T2338-","C2339-","C2340-","G2341-","T2342-","A2343-","T2344-","C2345-","C2346-","T2347-","A2348-","T2349-","T2350-","C2351-","C2352-","A2353-","C2354-","A2355-","C2356-","T2357-","T2358-","T2359-","G2360-","T2361-","T2362-","T2363-","T2364-","A2365-","G2366-","A2367-","A2368-","A2369-","T2370-","A2371-","C2372-","A2373-","T2374-","G2375-","T2376-","T2377-","C2378-","T2379-","A2380-","C2381-","A2382-","C2383-","C2384-","C2385-","T2386-","G2387-","A2388-","T2389-","G2390-","C2391-","T2392-","C2393-","C2394-","T2395-","T2396-","T2397-","G2398-","A2399-","G2400-","A2401-","A2402-","G2403-","A2404-","C2405-","A2406-","A2407-","T2408-","A2409-","A2410-","T2411-","A2412-","T2413-","C2414-","C2415-","T2416-","G2417-","G2418-","A2419-","G2420-","A2421-","G2422-","C2423-","A2424-","T2425-","T2426-","C2427-","A2428-","C2429-","A2430-","G2431-","A2432-","T2433-","T2434-","C2435-","T2436-","A2437-","T2438-","T2439-","G2440-","T2441-","G2442-","A2443-","G2444-","T2445-","C2446-","G2447-","T2448-","G2449-","T2450-","T2451-","A2452-","C2453-","A2454-","C2455-","G2456-","A2457-","T2458-","C2459-","G2460-","C2461-","G2462-","T2463-","C2464-","T2465-","C2466-","T2467-","A2468-","C2469-","C2470-","T2471-","G2472-","A2473-","T2474-","T2475-","A2476-","C2477-","T2478-","A2479-","T2480-","C2481-","A2482-","C2483-","A2484-","T2485-","C2486-","T2487-","T2488-","C2489-","C2490-","G2491-","T2492-","T2493-","A2494-","C2495-","A2496-","A2497-","C2498-","T2499-","T2500-","A2501-","G2502-","A2503-","C2504-","A2505-","A2506-","G2507-","C2508-","C2509-","T2510-","G2511-","T2512-","A2513-","A2514-","A2515-","T2516-","G2517-","A2518-","T2519-","T2520-","A2521-","T2522-","T2523-","G2524-","T2525-","G2526-","A2527-","G2528-","A2529-","T2530-","G2531-","T2532-","A2533-","A2534-","A2535-","G2536-","G2537-","T2538-","A2539-","T2540-","C2541-","C2542-","G2543-","A2544-","A2545-","C2546-","C2547-","A2548-","C2549-","A2550-","C2551-","G2552-","G2553-","T2554-","G2555-","T2556-","A2557-","C2558-","A2559-","T2560-","T2561-","G2562-","T2563-","G2564-","T2565-","A2566-","T2567-","T2568-","A2569-","G2570-","T2571-","C2572-","T2573-","T2574-","G2575-","C2576-","T2577-","A2578-","T2579-","C2580-","A2581-","C2582-","A2583-","T2584-","A2585-","A2586-","T2587-","C2588-","T2589-","G2590-","A2591-","A2592-","A2593-","G2594-","C2595-","G2596-","T2597-","A2598-","A2599-","G2600-","T2601-","T2602-","C2603-","C2604-","C2605-","G2606-","G2607-","A2608-","G2609-","G2610-","A2611-","C2612-","A2613-","C2614-","G2615-","A2616-","T2617-","A2618-","G2619-","A2620-","C2621-","A2622-","A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","T2653-","T2654-","T2655-","A2656-","C2657-","A2658-","C2659-","T2660-","T2661-","T2662-","C2663-","C2664-","A2665-","T2666-","T2667-","G2668-","G2669-","A2670-","T2671-","G2672-","G2673-","T2674-","G2675-","C2676-","A2677-","T2678-","G2679-","T2680-","G2681-","G2682-","T2683-","G2684-","C2685-","T2686-","A2687-","T2688-","A2689-","T2690-","C2691-","T2692-","C2693-","T2694-","T2695-","C2696-","C2697-","G2698-","T2699-","T2700-","T2701-","A2702-","T2703-","T2704-","A2705-","T2706-","T2707-","A2708-","T2709-","A2710-","C2711-","A2712-","T2713-","G2714-","A2715-","G2716-","A2717-","G2718-","A2719-","A2720-","A2721-","C2722-","A2723-","A2724-","T2725-","A2726-","T2727-","A2728-","T2729-","A2730-","C2731-","G2732-","A2733-","G2734-","T2735-","A2736-","T2737-","A2738-","A2739-","T2740-","A2741-","C2742-","G3104A","C20236T","C21206T","C134898T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C167792T","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","T179244-","C194106T","G194468-","T194469-","A194470-","T194471-","T194472-","A194473-","T194474-","A194475-","C194476-","T194477-","C194478-","G194479-","T194480-","A194481-","T194482-","A194483-","T194484-","A194485-","T194486-","T194487-","G194488-","T194489-","T194490-","T194491-","C194492-","T194493-","C194494-","T194495-","C194496-","A194497-","T194498-","G194499-","T194500-","A194501-","T194502-","A194503-","A194504-","T194505-","A194506-","A194507-","T194508-","A194509-","A194510-","A194511-","C194512-","G194513-","G194514-","A194515-","A194516-","G194517-","A194518-","G194519-","A194520-","T194521-","A194522-","T194523-","A194524-","G194525-","C194526-","A194527-","C194528-","C194529-","A194530-","C194531-","A194532-","T194533-","G194534-","C194535-","A194536-","C194537-","C194538-","A194539-","T194540-","C194541-","C194542-","A194543-","A194544-","T194545-","G194546-","G194547-","A194548-","A194549-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","C194595-","G194596-","T194597-","G194598-","T194599-","C194600-","C194601-","T194602-","C194603-","C194604-","G194605-","G194606-","G194607-","A194608-","A194609-","C194610-","T194611-","T194612-","A194613-","C194614-","G194615-","C194616-","T194617-","T194618-","T194619-","C194620-","A194621-","G194622-","A194623-","T194624-","T194625-","A194626-","T194627-","G194628-","T194629-","G194630-","A194631-","T194632-","A194633-","G194634-","C194635-","A194636-","A194637-","G194638-","A194639-","C194640-","T194641-","A194642-","A194643-","T194644-","A194645-","C194646-","A194647-","C194648-","A194649-","A194650-","T194651-","G194652-","T194653-","A194654-","C194655-","A194656-","C194657-","C194658-","G194659-","T194660-","G194661-","T194662-","G194663-","G194664-","T194665-","T194666-","C194667-","G194668-","G194669-","A194670-","T194671-","A194672-","C194673-","C194674-","T194675-","T194676-","T194677-","A194678-","C194679-","A194680-","T194681-","C194682-","T194683-","C194684-","A194685-","C194686-","A194687-","A194688-","T194689-","A194690-","A194691-","T194692-","C194693-","A194694-","T194695-","T194696-","T194697-","A194698-","C194699-","A194700-","G194701-","G194702-","C194703-","T194704-","T194705-","G194706-","T194707-","C194708-","T194709-","A194710-","A194711-","G194712-","T194713-","T194714-","G194715-","T194716-","A194717-","A194718-","C194719-","G194720-","G194721-","A194722-","A194723-","G194724-","A194725-","T194726-","G194727-","T194728-","G194729-","A194730-","T194731-","A194732-","G194733-","T194734-","A194735-","A194736-","T194737-","C194738-","A194739-","G194740-","G194741-","T194742-","A194743-","G194744-","A194745-","G194746-","A194747-","C194748-","G194749-","C194750-","G194751-","A194752-","T194753-","C194754-","G194755-","T194756-","G194757-","T194758-","A194759-","A194760-","C194761-","A194762-","C194763-","G194764-","A194765-","C194766-","T194767-","C194768-","A194769-","C194770-","A194771-","A194772-","T194773-","A194774-","G194775-","A194776-","A194777-","T194778-","C194779-","T194780-","G194781-","T194782-","G194783-","A194784-","A194785-","T194786-","G194787-","C194788-","T194789-","C194790-","T194791-","C194792-","C194793-","A194794-","G194795-","G194796-","A194797-","T194798-","A194799-","T194800-","T194801-","A194802-","T194803-","T194804-","G194805-","T194806-","C194807-","T194808-","T194809-","C194810-","T194811-","C194812-","A194813-","A194814-","A194815-","G194816-","G194817-","A194818-","G194819-","C194820-","A194821-","T194822-","C194823-","A194824-","G194825-","G194826-","G194827-","T194828-","G194829-","T194830-","A194831-","G194832-","A194833-","A194834-","C194835-","A194836-","T194837-","G194838-","T194839-","A194840-","T194841-","T194842-","T194843-","C194844-","T194845-","A194846-","A194847-","A194848-","A194849-","C194850-","A194851-","A194852-","A194853-","G194854-","T194855-","G194856-","T194857-","G194858-","G194859-","A194860-","A194861-","T194862-","A194863-","G194864-","G194865-","A194866-","T194867-","A194868-","C194869-","G194870-","G194871-","A194872-","G194873-","T194874-","A194875-","T194876-","C194877-","C194878-","G194879-","G194880-","A194881-","T194882-","A194883-","C194884-","A194885-","C194886-","G194887-","T194888-","C194889-","T194890-","A194891-","C194892-","C194893-","G194894-","G194895-","A194896-","G194897-","A194898-","C194899-","G194900-","T194901-","C194902-","A194903-","T194904-","C194905-","T194906-","G194907-","T194908-","T194909-","C194910-","T194911-","C194912-","C194913-","G194914-","T194915-","G194916-","T194917-","G194918-","G194919-","T194920-","C194921-","C194922-","C194923-","G194924-","G194925-","A194926-","A194927-","C194928-","A194929-","T194930-","A194931-","T194932-","T194933-","C194934-","T194935-","C194936-","A194937-","C194938-","A194939-","C194940-","C194941-","G194942-","T194943-","C194944-","T194945-","C194946-","T194947-","T194948-","C194949-","C194950-","A194951-","C194952-","A194953-","G194954-","A194955-","T194956-","A194957-","A194958-","A194959-","T194960-","G194961-","C194962-","G194963-","A194964-","A194965-","C194966-","C194967-","C194968-","G194969-","T194970-","C194971-","G194972-","T194973-","A194974-","A194975-","C194976-","C194977-","A194978-","G194979-","C194980-","A194981-","A194982-","T194983-","A194984-","C194985-","A194986-","T194987-","T194988-","T194989-","A194990-","A194991-","C194992-","T194993-","A194994-","T194995-","A194996-","T194997-","C194998-","G194999-","A195000-","T195001-","G195002-","T195003-","G195004-","G195005-","A195006-","A195007-","A195008-","T195009-","T195010-","A195011-","A195012-","C195013-","C195014-","T195015-","G195016-","T195017-","A195018-","T195019-","C195020-","C195021-","A195022-","G195023-","T195024-","C195025-","A195026-","A195027-","C195028-","G195029-","A195030-","C195031-","A195032-","C195033-","A195034-","T195035-","C195036-","G195037-","T195038-","G195039-","T195040-","A195041-","C195042-","T195043-","C195044-","G195045-","G195046-","A195047-","C195048-","G195049-","A195050-","C195051-","C195052-","A195053-","C195054-","T195055-","A195056-","C195057-","C195058-","G195059-","G195060-","T195061-","C195062-","T195063-","C195064-","A195065-","G195066-","C195067-"],"OPG002":["V4-","L5-","Y6-","S7-","Y8-","I9-","L10-","F11-","L12-","S13-","C14-","I15-","I16-","I17-","N18-","G19-","R20-","D21-","I22-","A23-","P24-","H25-","A26-","P27-","S28-","N29-","G30-","K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-","C47-","P48-","P49-","G50-","T51-","Y52-","A53-","F54-","R55-","L56-","C57-","D58-","S59-","K60-","T61-","N62-","T63-","Q64-","C65-","T66-","P67-","C68-","G69-","S70-","D71-","T72-","F73-","T74-","S75-","H76-","N77-","N78-","H79-","L80-","Q81-","A82-","C83-","L84-","S85-","C86-","N87-","G88-","R89-","C90-","D91-","S92-","N93-","Q94-","V95-","E96-","T97-","R98-","S99-","C100-","N101-","T102-","T103-","H104-","N105-","R106-","I107-","C108-","E109-","C110-","S111-","P112-","G113-","Y114-","Y115-","C116-","L117-","L118-","K119-","G120-","A121-","S122-","G123-","C124-","R125-","T126-","C127-","I128-","S129-","K130-","T131-","K132-","C133-","G134-","I135-","G136-","Y137-","G138-","V139-","S140-","G141-","Y142-","T143-","S144-","T145-","G146-","D147-","V148-","I149-","C150-","S151-","P152-","C153-","G154-","P155-","G156-","T157-","Y158-","S159-","H160-","T161-","V162-","S163-","S164-","T165-","D166-","K167-","C168-","E169-","P170-","V171-","V172-","T173-","S174-","N175-","T176-","F177-","N178-","Y179-","I180-","D181-","V182-","E183-","I184-","N185-","L186-","Y187-","P188-","V189-","N190-","D191-","T192-","S193-","C194-","T195-","R196-","T197-","T198-","T199-","T200-","G201-","L202-","S203-"],"OPG002_dup":["V4-","L5-","Y6-","S7-","Y8-","I9-","L10-","F11-","L12-","S13-","C14-","I15-","I16-","I17-","N18-","G19-","R20-","D21-","I22-","A23-","P24-","H25-","A26-","P27-","S28-","N29-","G30-","K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-","C47-","P48-","P49-","G50-","T51-","Y52-","A53-","F54-","R55-","L56-","C57-","D58-","S59-","K60-","T61-","N62-","T63-","Q64-","C65-","T66-","P67-","C68-","G69-","S70-","D71-","T72-","F73-","T74-","S75-","H76-","N77-","N78-","H79-","L80-","Q81-","A82-","C83-","L84-","S85-","C86-","N87-","G88-","R89-","C90-","D91-","S92-","N93-","Q94-","V95-","E96-","T97-","R98-","S99-","C100-","N101-","T102-","T103-","H104-","N105-","R106-","I107-","C108-","E109-","C110-","S111-","P112-","G113-","Y114-","Y115-","C116-","L117-","L118-","K119-","G120-","A121-","S122-","G123-","C124-","R125-","T126-","C127-","I128-","S129-","K130-","T131-","K132-","C133-","G134-","I135-","G136-","Y137-","G138-","V139-","S140-","G141-","Y142-","T143-","S144-","T145-","G146-","D147-","V148-","I149-","C150-","S151-","P152-","C153-","G154-","P155-","G156-","T157-","Y158-","S159-","H160-","T161-","V162-","S163-","S164-","T165-","D166-","K167-","C168-","E169-","P170-","V171-","V172-","T173-","S174-","N175-","T176-","F177-","N178-","Y179-","I180-","D181-","V182-","E183-","I184-","N185-","L186-","Y187-","P188-","V189-","N190-","D191-","T192-","S193-","C194-","T195-","R196-","T197-","T198-","T199-","T200-","G201-","L202-","S203-"],"OPG003":["H502Y"],"OPG003_dup":["H502Y"],"OPG035":["D57N"],"OPG037":["D410N"]},"labels":{"aa":"OPG002: V4-, L5-, Y6-, S7-, Y8-, I9-, L10-, F11-, L12-, S13-, C14-, I15-, I16-, I17-, N18-, G19-, R20-, D21-, I22-, A23-, P24-, H25-, A26-, P27-, S28-, N29-, G30-, K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-, C47-, P48-, P49-, G50-, T51-, Y52-, A53-, F54-, R55-, L56-, C57-, D58-, S59-, K60-, T61-, N62-, T63-, Q64-, C65-, T66-, P67-, C68-, G69-, S70-, D71-, T72-, F73-, T74-, S75-, H76-, N77-, N78-, H79-, L80-, Q81-, A82-, C83-, L84-, S85-, C86-, N87-, G88-, R89-, C90-, D91-, S92-, N93-, Q94-, V95-, E96-, T97-, R98-, S99-, C100-, N101-, T102-, T103-, H104-, N105-, R106-, I107-, C108-, E109-, C110-, S111-, P112-, G113-, Y114-, Y115-, C116-, L117-, L118-, K119-, G120-, A121-, S122-, G123-, C124-, R125-, T126-, C127-, I128-, S129-, K130-, T131-, K132-, C133-, G134-, I135-, G136-, Y137-, G138-, V139-, S140-, G141-, Y142-, T143-, S144-, T145-, G146-, D147-, V148-, I149-, C150-, S151-, P152-, C153-, G154-, P155-, G156-, T157-, Y158-, S159-, H160-, T161-, V162-, S163-, S164-, T165-, D166-, K167-, C168-, E169-, P170-, V171-, V172-, T173-, S174-, N175-, T176-, F177-, N178-, Y179-, I180-, D181-, V182-, E183-, I184-, N185-, L186-, Y187-, P188-, V189-, N190-, D191-, T192-, S193-, C194-, T195-, R196-, T197-, T198-, T199-, T200-, G201-, L202-, S203-; OPG002_dup: V4-, L5-, Y6-, S7-, Y8-, I9-, L10-, F11-, L12-, S13-, C14-, I15-, I16-, I17-, N18-, G19-, R20-, D21-, I22-, A23-, P24-, H25-, A26-, P27-, S28-, N29-, G30-, K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-, C47-, P48-, P49-, G50-, T51-, Y52-, A53-, F54-, R55-, L56-, C57-, D58-, S59-, K60-, T61-, N62-, T63-, Q64-, C65-, T66-, P67-, C68-, G69-, S70-, D71-, T72-, F73-, T74-, S75-, H76-, N77-, N78-, H79-, L80-, Q81-, A82-, C83-, L84-, S85-, C86-, N87-, G88-, R89-, C90-, D91-, S92-, N93-, Q94-, V95-, E96-, T97-, R98-, S99-, C100-, N101-, T102-, T103-, H104-, N105-, R106-, I107-, C108-, E109-, C110-, S111-, P112-, G113-, Y114-, Y115-, C116-, L117-, L118-, K119-, G120-, A121-, S122-, G123-, C124-, R125-, T126-, C127-, I128-, S129-, K130-, T131-, K132-, C133-, G134-, I135-, G136-, Y137-, G138-, V139-, S140-, G141-, Y142-, T143-, S144-, T145-, G146-, D147-, V148-, I149-, C150-, S151-, P152-, C153-, G154-, P155-, G156-, T157-, Y158-, S159-, H160-, T161-, V162-, S163-, S164-, T165-, D166-, K167-, C168-, E169-, P170-, V171-, V172-, T173-, S174-, N175-, T176-, F177-, N178-, Y179-, I180-, D181-, V182-, E183-, I184-, N185-, L186-, Y187-, P188-, V189-, N190-, D191-, T192-, S193-, C194-, T195-, R196-, T197-, T198-, T199-, T200-, G201-, L202-, S203-; OPG003: H502Y; OPG003_dup: H502Y; OPG035: D57N; OPG037: D410N"}}},{"name":"OP390178","node_attrs":{"div":560,"accession":"OP390178","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"country":{"value":"Colombia"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MAG-UNIMOL-MPX-292982-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-20"},"strain_display":{"value":"Colombia/OP390178/2022-08-20"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP555545","node_attrs":{"div":560,"accession":"OP555545","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"Monkeypox/PT0466/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-05"},"strain_display":{"value":"Portugal/OP555545/2022-08-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-"]}}},{"name":"OP536709","node_attrs":{"div":561,"accession":"OP536709","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"country":{"value":"USA"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV-USA-IL-IDPH-048"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-23"},"strain_display":{"value":"USA/OP536709/2022-06-23"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","T48717A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG068":["L173I"]},"labels":{"aa":"OPG068: L173I"}}},{"name":"OP524006","node_attrs":{"div":561,"accession":"OP524006","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV/Germany/2022/RKI404"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP524006/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","G182634A","-196615A"],"OPG210":["D427N"]},"labels":{"aa":"OPG210: D427N"}}},{"name":"OP879738","node_attrs":{"div":560,"accession":"OP879738","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"country":{"value":"USA"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"NJ-MPXV-020-rep2"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-06"},"strain_display":{"value":"USA/OP879738/2022-07-06"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-"]}}},{"name":"OP819960","node_attrs":{"div":563,"accession":"OP819960","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"SAN_INS_MPX_0973_L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-17"},"strain_display":{"value":"Colombia/OP819960/2022-10-17"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["A19748-","G19749-","G19750-","C19751-","G19752-","T19753-","G27840A","C64404T","C96810T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG034":["T87-","P88-"],"OPG043":["S39F"],"OPG083":["D105N"]},"labels":{"aa":"OPG034: T87-, P88-; OPG043: S39F; OPG083: D105N"}}},{"name":"OP743993","node_attrs":{"div":563,"accession":"OP743993","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MpxV/human/USA/WA-UW-094603/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OP743993/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","G52594A","C89777T","G176818A","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG110":["P49L"],"OPG205":["R388Q"]},"labels":{"aa":"OPG110: P49L; OPG205: R388Q"}}},{"name":"OP693656","node_attrs":{"div":562,"accession":"OP693656","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"CUN_INS_MPX_0751_C"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-10"},"strain_display":{"value":"Colombia/OP693656/2022-09-10"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C33832T","C42036T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG052":["R55Q"]},"labels":{"aa":"OPG052: R55Q"}}},{"name":"OP920682","node_attrs":{"div":562,"accession":"OP920682","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00344/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-09"},"strain_display":{"value":"USA/OP920682/2022-11-09"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","G39327A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177273A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","-196615A"],"OPG057":["A290V"],"OPG205":["D540N"]},"labels":{"aa":"OPG057: A290V; OPG205: D540N"}}},{"name":"OQ427115","node_attrs":{"div":563,"accession":"OQ427115","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV_USA_2022_NY0040"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ427115/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C2446T","G126646A","C160354T","-179194A","-179195T","-179196A","-179197T","-179198A","G194764A"],"OPG148":["E221K"]},"labels":{"aa":"OPG148: E221K"}}},{"name":"OR035719","node_attrs":{"div":563,"accession":"OR035719","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV/UZ_REGA_113"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035719/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T133102-","C142797T","C167995T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G189258A"],"OPG164":["S7L"],"OPG193":["S221F"]},"labels":{"aa":"OPG164: S7L; OPG193: S221F"}}},{"name":"OQ957072","node_attrs":{"div":563,"accession":"OQ957072","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"ANT-LDSP-ANT-MPX-3668E"},"date":{"value":"2023-02-16"},"strain_display":{"value":"Colombia/OQ957072/2023-02-16"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C35308T","G71777A","C120979T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG054":["R230H"],"OPG138":["D52N"]},"labels":{"aa":"OPG054: R230H; OPG138: D52N"}}},{"name":"OQ696092","node_attrs":{"div":564,"accession":"OQ696092","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"ANT-LDSP-ANT-MPX-29706O"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-03"},"strain_display":{"value":"Colombia/OQ696092/2022-11-03"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G17023A","G74462A","C80742T","G113382A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","T196988-","A196989-","A196990-"],"OPG029":["S16F"],"OPG094":["R228K"],"OPG104":["R93Q"]},"labels":{"aa":"OPG029: S16F; OPG094: R228K; OPG104: R93Q"}}},{"name":"OR095053","node_attrs":{"div":560,"accession":"OR095053","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV/UZ_REGA_235/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-12"},"strain_display":{"value":"Belgium/OR095053/2022-08-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR464206","node_attrs":{"div":563,"accession":"OR464206","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV_USA_2022_TN0020"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR464206/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","G19458A","G74374A","-179194A","-179195T","-179196A","-179197T","-179198A","C185455T","-196615A"],"OPG034":["S183L"],"OPG094":["E199K"],"OPG210":["S1367L"]},"labels":{"aa":"OPG034: S183L; OPG094: E199K; OPG210: S1367L"}}}]},{"name":"NODE_0000149","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G36617A","C159779T"],"OPG055":["S156L"],"OPG185":["S288L"]},"labels":{"aa":"OPG055: S156L; OPG185: S288L","clade":"B.1.14"}},"children":[{"name":"ON959133","node_attrs":{"div":558,"accession":"ON959133","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV_USA_2022_NY002"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/ON959133/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"]}}},{"name":"ON694342","node_attrs":{"div":558,"accession":"ON694342","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/RKI011"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/ON694342/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP378704","node_attrs":{"div":561,"accession":"OP378704","author":{"author":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y.","value":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV_USA_2022_TX0010"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP378704/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C8552T","C8597T","G46179A","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A","-196616A"],"OPG065":["S102L"]},"labels":{"aa":"OPG065: S102L"}}},{"name":"OP355563","node_attrs":{"div":558,"accession":"OP355563","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/ON/RKI302"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP355563/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","A188351-"]}}},{"name":"OP626108","node_attrs":{"div":560,"accession":"OP626108","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/RKI470"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OP626108/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G53788A","G107868A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG126":["S88F"]},"labels":{"aa":"OPG126: S88F"}}},{"name":"OP837350","node_attrs":{"div":559,"accession":"OP837350","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/RKI588"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OP837350/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C84008T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OQ274887","node_attrs":{"div":558,"accession":"OQ274887","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/ON/RKI668"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ274887/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A152676-","T152686-"]}}},{"name":"OR035646","node_attrs":{"div":562,"accession":"OR035646","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/UZ_REGA_40"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR035646/2022-07-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C22880T","G158617A","C170573T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C183790T"],"OPG038":["E94K"],"OPG198":["S179L"],"OPG210":["S812L"]},"labels":{"aa":"OPG038: E94K; OPG198: S179L; OPG210: S812L"}}},{"name":"OR086995","node_attrs":{"div":559,"accession":"OR086995","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/UZ_REGA_186/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-03"},"strain_display":{"value":"Belgium/OR086995/2022-08-03"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G146441A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG170":["S113F"]},"labels":{"aa":"OPG170: S113F"}}},{"name":"OX009124","node_attrs":{"div":560,"accession":"OX009124","author":{"author":"Pettke,A.,Filen,F.,Asgeirsson,H.,Glans,H.,Widgren,K.,Muradrasoli,S.,Helgesson,S.,Karlberg,M.L.,Walai,N.,Bjerkner,A.,Gourle,H.,Lindsjo,O.K.,Sonden,K.","value":"Pettke,A.,Filen,F.,Asgeirsson,H.,Glans,H.,Widgren,K.,Muradrasoli,S.,Helgesson,S.,Karlberg,M.L.,Walai,N.,Bjerkner,A.,Gourle,H.,Lindsjo,O.K.,Sonden,K."},"country":{"value":"Sweden"},"institution":{"value":"Public Health Agency of Sweden, Unit for Laboratory Development and Technology Transfer , Folkhalsomyndigheten, 171 82 Solna"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"Lesion"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-22"},"strain_display":{"value":"Sweden/OX009124/2022-05-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T602-","T603-","T604-","T605-","T606-","A8055-","A28529-","A28530-","T47054-","T76087-","T88836-","A91705-","A92907-","T103367-","T104687-","T148344A","A148345T","A151680-","A162904-","T163342-","T163597-","A170728-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG044":["K147-"],"OPG113":["I393-"],"OPG178":["T58-"],"OPG188":["K437-"],"OPG189":["F4-"],"OPG198":["K231-"]},"labels":{"aa":"OPG044: K147-; OPG113: I393-; OPG178: T58-; OPG188: K437-; OPG189: F4-; OPG198: K231-"}}},{"name":"NODE_0000150","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G28021A"]}},"children":[{"name":"OR026629","node_attrs":{"div":560,"accession":"OR026629","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"country":{"value":"USA"},"institution":{"value":"Utah Public Health Laboratory, Utah Public Health Laboratory Infectious Disease submission group"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200382/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-09"},"strain_display":{"value":"USA/OR026629/2022-09-09"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C148666T"],"OPG174":["A244T"]},"labels":{"aa":"OPG174: A244T"}}},{"name":"NODE_0000151","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G181818A"],"OPG210":["A155T"]},"labels":{"aa":"OPG210: A155T"}},"children":[{"name":"OP539922","node_attrs":{"div":561,"accession":"OP539922","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00137/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-09"},"strain_display":{"value":"USA/OP539922/2022-08-09"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G109793A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G168211-","G168212-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP743362","node_attrs":{"div":561,"accession":"OP743362","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"country":{"value":"USA"},"institution":{"value":"Utah Public Health Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200104/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-21"},"strain_display":{"value":"USA/OP743362/2022-07-21"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A19512C"],"OPG034":["I165R"]},"labels":{"aa":"OPG034: I165R"}}}]}]},{"name":"NODE_0000152","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G171270A","-196615A","-196616T"],"OPG199":["D95N"]},"labels":{"aa":"OPG199: D95N"}},"children":[{"name":"OP382492","node_attrs":{"div":560,"accession":"OP382492","author":{"author":"Colson,P.","value":"Colson,P."},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"hMPXV-IHU00015"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-22"},"strain_display":{"value":"France/OP382492/2022-07-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G161913A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196856-","A196857-","A196858-"]}}},{"name":"OP494266","node_attrs":{"div":559,"accession":"OP494266","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/ON/RKI320"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP494266/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OP605553","node_attrs":{"div":559,"accession":"OP605553","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"Slovenia-MPXV-10-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Slovenia/OP605553/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","T196950-","A196951-","A196952-"]}}},{"name":"OP555644","node_attrs":{"div":561,"accession":"OP555644","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"Monkeypox/PT0573/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-06"},"strain_display":{"value":"Portugal/OP555644/2022-09-06"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","C93713T","G158549A"]}}},{"name":"OP555562","node_attrs":{"div":559,"accession":"OP555562","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.14"},"strain":{"value":"Monkeypox/PT0486/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-09"},"strain_display":{"value":"Portugal/OP555562/2022-08-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000153","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G34308A"],"OPG053":["S128L"]},"labels":{"aa":"OPG053: S128L","clade":"B.1.4"}},"children":[{"name":"ON880519","node_attrs":{"div":558,"accession":"ON880519","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-2833/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-13"},"strain_display":{"value":"Canada/ON880519/2022-05-13"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T85846C"],"OPG107":["M112T"]},"labels":{"aa":"OPG107: M112T"}}},{"name":"OP390177","node_attrs":{"div":558,"accession":"OP390177","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"country":{"value":"Colombia"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"ATL-UNIMOL-MPX-292896-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-13"},"strain_display":{"value":"Colombia/OP390177/2022-08-13"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C176447T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"NODE_0000154","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C10672T","G112481A","G163626A"],"OPG022":["E63K"]},"labels":{"aa":"OPG022: E63K"}},"children":[{"name":"OR126132","node_attrs":{"div":564,"accession":"OR126132","author":{"author":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C.","value":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C."},"country":{"value":"Spain"},"institution":{"value":"Hospital Ramon y Cajal, Microbiology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"HRYC_MPXV002"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-23"},"strain_display":{"value":"Spain/OR126132/2023-03-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G6376A","G11924A","G21674A","A87705G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C190834T"],"OPG016":["S142L"],"OPG023":["S326L"],"OPG037":["L254F"]},"labels":{"aa":"OPG016: S142L; OPG023: S326L; OPG037: L254F"}}},{"name":"NODE_0000155","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G144478A"]}},"children":[{"name":"ON880511","node_attrs":{"div":561,"accession":"ON880511","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-3214/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Canada/ON880511/2022-05-30"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"OP752106","node_attrs":{"div":564,"accession":"OP752106","author":{"author":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Morrison,S.S.,Desch,M.,Knipe,K.,Weigand,M.R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Morrison,S.S.,Desch,M.,Knipe,K.,Weigand,M.R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPXV_USA_2022_FL0025"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OP752106/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C57339T","T173285-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","G176716A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","G185991A"],"OPG075":["E54K"],"OPG205":["G354D"],"OPG210":["D1546N"]},"labels":{"aa":"OPG075: E54K; OPG205: G354D; OPG210: D1546N"}}},{"name":"OR759176","node_attrs":{"div":564,"accession":"OR759176","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"hMpxV/Canada/ON-PHOL088/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759176/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","C128534T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C151626T","G170076A"],"OPG178":["Q40*"]},"labels":{"aa":"OPG178: Q40*"}}},{"name":"OR759160","node_attrs":{"div":561,"accession":"OR759160","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"hMpxV/Canada/ON-PHOL064/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759160/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}}]}]},{"name":"NODE_0000156","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C24995T","G85774A","G148427A","G189258A"],"OPG040":["D162N"],"OPG107":["R88K"]},"labels":{"aa":"OPG040: D162N; OPG107: R88K"}},"children":[{"name":"ON983163","node_attrs":{"div":561,"accession":"ON983163","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-3532/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-07"},"strain_display":{"value":"Canada/ON983163/2022-06-07"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"ON803414","node_attrs":{"div":561,"accession":"ON803414","author":{"author":"Knox,N.,Hole,D.,Duggan,A.,Yadav,C.,Haidl,E.,Chapel,M.,Graham,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Hagan,M.,Griffiths,E.,Leung,A.,Safronetz,D.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Knox,N.,Hole,D.,Duggan,A.,Yadav,C.,Haidl,E.,Chapel,M.,Graham,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Hagan,M.,Griffiths,E.,Leung,A.,Safronetz,D.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-2930/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-21"},"strain_display":{"value":"Canada/ON803414/2022-05-21"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP279035","node_attrs":{"div":561,"accession":"OP279035","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-4103/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-04"},"strain_display":{"value":"Canada/OP279035/2022-07-04"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ427147","node_attrs":{"div":562,"accession":"OQ427147","author":{"author":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPXV_USA_2022_IL0006"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OQ427147/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G131810A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG151":["D963N"]},"labels":{"aa":"OPG151: D963N"}}},{"name":"NODE_0000157","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G45236A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP279043","node_attrs":{"div":562,"accession":"OP279043","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-4140/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-30"},"strain_display":{"value":"Canada/OP279043/2022-06-30"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OP415246","node_attrs":{"div":563,"accession":"OP415246","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPX_J6xzTO_9000286"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415246/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G174962A"],"OPG204":["R144K"]},"labels":{"aa":"OPG204: R144K"}}}]}]},{"name":"NODE_0000158","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G36259A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G174543A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}},"children":[{"name":"OP626135","node_attrs":{"div":562,"accession":"OP626135","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPXV/Germany/2022/RKI496"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP626135/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C40251T","C154472T","G167517A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"],"OPG058":["D62N"],"OPG181":["H21Y"],"OPG193":["E62K"]},"labels":{"aa":"OPG058: D62N; OPG181: H21Y; OPG193: E62K"}}},{"name":"OQ547900","node_attrs":{"div":561,"accession":"OQ547900","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"country":{"value":"USA"},"institution":{"value":"CDPH, VRDL"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000185/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-21"},"strain_display":{"value":"USA/OQ547900/2022-12-21"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T6976-","G92733A","C177720T"],"OPG113":["E335K"],"OPG205":["R689C"]},"labels":{"aa":"OPG113: E335K; OPG205: R689C"}}},{"name":"NODE_0000159","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C25967T"],"OPG042":["W377*"]},"labels":{"aa":"OPG042: W377*"}},"children":[{"name":"OP442553","node_attrs":{"div":561,"accession":"OP442553","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00086/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"USA/OP442553/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C188775T"]}}},{"name":"NODE_0000160","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C172792T"]}},"children":[{"name":"OP920681","node_attrs":{"div":562,"accession":"OP920681","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00343/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-10"},"strain_display":{"value":"USA/OP920681/2022-11-10"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A763-","A764-","T765-","C97805T"],"OPG117":["P586L"]},"labels":{"aa":"OPG117: P586L"}}},{"name":"NODE_0000161","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","A150591-","T150592-","A150595-","T150596-","A150597-","T150598-","A150600-","T150601-","A163469T"],"OPG189":["E46V"]},"labels":{"aa":"OPG189: E46V"}},"children":[{"name":"OQ503786","node_attrs":{"div":570,"accession":"OQ503786","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00452/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-12"},"strain_display":{"value":"USA/OQ503786/2022-10-12"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G70435A","C125412T","C141442T","C141511T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G158709A","T172792C","G175698A","G176439A"],"OPG145":["S489L"],"OPG161":["S114L","S137F"],"OPG205":["D15N","D262N"]},"labels":{"aa":"OPG145: S489L; OPG161: S114L, S137F; OPG205: D15N, D262N"}}},{"name":"OQ503765","node_attrs":{"div":562,"accession":"OQ503765","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/USA/WA-UW-091026/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ503765/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]}]}]}]}]},{"name":"NODE_0000162","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G5595A","C191615T"],"OPG015":["Q188*"],"OPG015_dup":["Q188*"]},"labels":{"aa":"OPG015: Q188*; OPG015_dup: Q188*","clade":"B.1.8"}},"children":[{"name":"OP215224","node_attrs":{"div":557,"accession":"OP215224","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/RKI235"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP215224/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000163","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G161296A","-179188T","-179189A","C196308T"],"OPG001_dup":["S225L"]},"labels":{"aa":"OPG001_dup: S225L"}},"children":[{"name":"OP331337","node_attrs":{"div":558,"accession":"OP331337","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV_UK_2022_9000183"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-29"},"strain_display":{"value":"United Kingdom/OP331337/2022-06-29"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G902A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG001":["S225L"]},"labels":{"aa":"OPG001: S225L"}}},{"name":"OP555609","node_attrs":{"div":560,"accession":"OP555609","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"Monkeypox/PT0538/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-23"},"strain_display":{"value":"Portugal/OP555609/2022-08-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","G902A","C25269T","G25692A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179188-","A179189-"],"OPG001":["S225L"]},"labels":{"aa":"OPG001: S225L"}}},{"name":"OP863250","node_attrs":{"div":561,"accession":"OP863250","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/ON/RKI600"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP863250/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G89716A","G128858A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","G181052-","C186220T"],"OPG110":["E29K"],"OPG209":["G179-"],"OPG210":["A1622V"]},"labels":{"aa":"OPG110: E29K; OPG209: G179-; OPG210: A1622V"}}},{"name":"OR030928","node_attrs":{"div":559,"accession":"OR030928","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/UZ_REGA_17"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-19"},"strain_display":{"value":"Belgium/OR030928/2022-07-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G902A","C68981T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG001":["S225L"],"OPG087":["S42L"]},"labels":{"aa":"OPG001: S225L; OPG087: S42L"}}},{"name":"OR449625","node_attrs":{"div":558,"accession":"OR449625","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/ON/RKI912"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449625/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150562-","A150563-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"NODE_0000164","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C80545T","T196308C"],"OPG001_dup":["L225S"],"OPG103":["S182L"]},"labels":{"aa":"OPG001_dup: L225S; OPG103: S182L"}},"children":[{"name":"ON929089","node_attrs":{"div":559,"accession":"ON929089","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/RKI134"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/ON929089/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179188-","A179189-"]}}},{"name":"NODE_0000165","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G102614A","C170573T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG122":["V63I"],"OPG198":["S179L"]},"labels":{"aa":"OPG122: V63I; OPG198: S179L"}},"children":[{"name":"OR035714","node_attrs":{"div":561,"accession":"OR035714","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/UZ_REGA_108"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035714/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OR095062","node_attrs":{"div":562,"accession":"OR095062","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/UZ_REGA_244/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-16"},"strain_display":{"value":"Belgium/OR095062/2022-08-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C62305T"]}}}]}]}]},{"name":"NODE_0000166","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G78034A","C80111T"],"OPG099":["D124N"]},"labels":{"aa":"OPG099: D124N"}},"children":[{"name":"ON622718","node_attrs":{"div":560,"accession":"ON622718","author":{"author":"Martinez-Puchol,S.,Coello,A.,Bordoy,A.E.,Soler,L.,Panisello,D.,Gonzalez-Gomez,S.,Clara,G.,Paris de Leon,A.,Not,A.,Hernandez,A.,Bofill-Mas,S.,Saludes,V.,Blanco,I.,Martro,E.,Cardona,P.-J.","value":"Martinez-Puchol,S.,Coello,A.,Bordoy,A.E.,Soler,L.,Panisello,D.,Gonzalez-Gomez,S.,Clara,G.,Paris de Leon,A.,Not,A.,Hernandez,A.,Bofill-Mas,S.,Saludes,V.,Blanco,I.,Martro,E.,Cardona,P.-J."},"country":{"value":"Spain"},"institution":{"value":"Microbiology, Hospital Universitari Germans Trias i Pujol, Spain"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/ES0001/HUGTiP/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-20"},"strain_display":{"value":"Spain/ON622718/2022-05-20"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C14113-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T139150C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","-196615A","-196616A"],"OPG156":["Q87R"]},"labels":{"aa":"OPG156: Q87R"}}},{"name":"NODE_0000167","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G22643A","G63811A"],"OPG038":["H173Y"]},"labels":{"aa":"OPG038: H173Y"}},"children":[{"name":"OP378705","node_attrs":{"div":561,"accession":"OP378705","author":{"author":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y.","value":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV_USA_2022_TX0011"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP378705/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP459214","node_attrs":{"div":561,"accession":"OP459214","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"ANT-LDSP-ANT-MPX-23631-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-30"},"strain_display":{"value":"Colombia/OP459214/2022-08-30"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP642374","node_attrs":{"div":562,"accession":"OP642374","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"ANT-LDSP-ANT-MPX-24722-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-08"},"strain_display":{"value":"Colombia/OP642374/2022-09-08"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G168759A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG195":["R177K"]},"labels":{"aa":"OPG195: R177K"}}},{"name":"OP626136","node_attrs":{"div":563,"accession":"OP626136","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/RKI497"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP626136/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C64635T","G141114A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG083":["A28T"],"OPG161":["E5K"]},"labels":{"aa":"OPG083: A28T; OPG161: E5K"}}},{"name":"OQ320513","node_attrs":{"div":565,"accession":"OQ320513","author":{"author":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y.","value":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV_USA_2022_FL0009"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ320513/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G4038A","A39081T","C67289T","G73790A","T133102-","A173284-","T173285-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C193172T"],"OPG057":["I372N"],"OPG085":["E415K"],"OPG094":["G4E"]},"labels":{"aa":"OPG057: I372N; OPG085: E415K; OPG094: G4E"}}},{"name":"OQ557957","node_attrs":{"div":563,"accession":"OQ557957","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV_USA_2022_TX0047"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OQ557957/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C84485T","C127215T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG149":["S7L"]},"labels":{"aa":"OPG149: S7L"}}},{"name":"OQ721943","node_attrs":{"div":564,"accession":"OQ721943","author":{"author":"Gigante,C.,Segaloff,H.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Florek,K.,Li,Y.","value":"Gigante,C.,Segaloff,H.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Florek,K.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV_USA_2022_WI0002"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721943/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G22108A","G93387A","C144233T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"],"OPG037":["S109L"],"OPG113":["E553K"],"OPG165":["Q240*"]},"labels":{"aa":"OPG037: S109L; OPG113: E553K; OPG165: Q240*"}}},{"name":"OR759149","node_attrs":{"div":565,"accession":"OR759149","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"hMpxV/Canada/ON-PHOL055/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759149/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C8555T","G95862A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168089T","G181674A","-196615A"],"OPG116":["A168T"],"OPG210":["E107K"]},"labels":{"aa":"OPG116: A168T; OPG210: E107K"}}},{"name":"NODE_0000168","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T119985C"]}},"children":[{"name":"OP415254","node_attrs":{"div":563,"accession":"OP415254","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPX_imBNaw_9000300"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415254/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G189258A"]}}},{"name":"OP597796","node_attrs":{"div":562,"accession":"OP597796","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"country":{"value":"USA"},"institution":{"value":"Minnesota Department of Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.8"},"strain":{"value":"MN-MDH-MPXV_0022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-18"},"strain_display":{"value":"USA/OP597796/2022-07-18"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}}]}]}]}]},{"name":"NODE_0000169","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C89906T","G94798A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG110":["S92F"],"OPG115":["E47K"]},"labels":{"aa":"OPG110: S92F; OPG115: E47K","clade":"B.1.10"}},"children":[{"name":"ON720848","node_attrs":{"div":559,"accession":"ON720848","author":{"author":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"country":{"value":"Spain"},"institution":{"value":"Microbial Genomics, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MpxV/Spain/MD-HGUGM-6513479/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-27"},"strain_display":{"value":"Spain/ON720848/2022-05-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A327-","T605-","T606-","A1697-","T4296-","T6587-","T6588-","T7253-","G7724-","T8017-","A8036-","T8499-","T9514-","A9869-","T10502-","A10914-","T11188-","C11749-","T11761-","T12121-","A15754-","A17087-","T18866-","A19360-","T20663-","A21081-","T21975-","T24678-","T25853-","T26099-","C27002-","A27114-","C27799-","A28529-","A28530-","T32194-","T33414-","G35949-","T37982-","T39131-","T39866-","T41744-","T42990-","C43014-","G43200-","A43443-","T44120-","T44738-","G46762-","T48675-","A49134-","G49833-","A51022-","A52765-","A54968-","A55124-","T55560-","T56040-","T57075-","A57277-","A58650-","T61749-","A62041-","T63628-","A64728-","A64935-","A65535-","A65967-","T66783-","A66843-","A67164-","C68466-","T68481-","C68899-","G69145-","A69744-","T69768-","A71254-","G71359-","T75833-","A76072-","T76084-","T76085-","A76153-","A76154-","A76890-","A77260-","T77803-","T78062-","A79042-","A79181-","G79217-","C79533T","A79787-","G80950-","C82482-","T84846-","T88095-","T88836-","T88941-","A89106-","T90646-","T91129-","T91370-","A91583-","A91705-","T94795-","A95341-","A95574-","G95742-","G95818-","A97351-","A97480-","A97501-","A97699-","A98683-","T101452-","G101515-","T102437-","T103367-","T103368-","T104279-","T105360-","T106596-","T108598-","A113921-","T113951-","C114431-","T114518-","T114755-","T115127-","G115801-","A116014-","C116494-","T116963-","T121121-","T121122-","G121269-","C121546-","T124022-","T124751-","A125249-","A126568-","T126682-","A126715-","A127250-","A127754-","A132023-","A132024-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133639-","T136780-","T137886-","A143045-","G143363-","T143478-","A144230-","T146131-","A148000-","A149727-","A150340-","T150538-","T150539-","A150635-","T150864-","A151490-","A151508-","G151545-","A152676-","T152686-","A153358-","A153424-","A153517-","T154862-","T155424-","C156607-","C156608-","A157997-","T163498-","T163597-","A163957-","A165461-","A166740-","G167640-","A167967-","T168120-","A170728-","T170758-","T170903-","T170904-","T172087-","T172667-","G179036-","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","A179551-","A179950-","T180905-","G181052-","A181253-","C183534-","A183780-","T187080-","A190935-","A191015-","G191519-","A196613-","A196614-","T196888-","T197183-"],"OPG015_dup":["G156-"],"OPG016":["T176-"],"OPG019":["G49-"],"OPG021":["N95-"],"OPG023":["G385-"],"OPG043":["G53-"],"OPG044":["K147-"],"OPG066":["P223-"],"OPG068":["L159-","D545-"],"OPG070":["N145-"],"OPG074":["K523-"],"OPG084":["K3-","K272-","R416-"],"OPG085":["F457-"],"OPG087":["L15-","G97-"],"OPG090":["K26-"],"OPG096":["L83-"],"OPG098":["S121-"],"OPG099":["F47-"],"OPG100":["F19-"],"OPG102":["K33-"],"OPG104":["P24-"],"OPG109":["K206-"],"OPG111":["F128-"],"OPG112":["S42-"],"OPG115":["S46-"],"OPG116":["K72-"],"OPG117":["K435-","N478-","R551-"],"OPG118":["I80-"],"OPG122":["Y4-"],"OPG123":["K569-"],"OPG133":["K394-"],"OPG134":["E18-","P249-"],"OPG139":["P34-"],"OPG145":["F26-","F269-","K435-"],"OPG148":["I195-","F233-"],"OPG149":["K19-"],"OPG151":["K1034-"],"OPG164":["R90-"],"OPG165":["M239-"],"OPG172":["I192-"],"OPG175":["N96-"],"OPG176":["K178-"],"OPG178":["D13-"],"OPG180":["K223-","K276-"],"OPG181":["F151-"],"OPG189":["L56-","K209-"],"OPG190":["N114-"],"OPG192":["K4-"],"OPG193":["G103-","F263-"],"OPG198":["K231-"],"OPG208":["I96-"],"OPG209":["L130-"],"OPG210":["P727-"]},"labels":{"aa":"OPG015_dup: G156-; OPG016: T176-; OPG019: G49-; OPG021: N95-; OPG023: G385-; OPG043: G53-; OPG044: K147-; OPG066: P223-; OPG068: L159-, D545-; OPG070: N145-; OPG074: K523-; OPG084: K3-, K272-, R416-; OPG085: F457-; OPG087: L15-, G97-; OPG090: K26-; OPG096: L83-; OPG098: S121-; OPG099: F47-; OPG100: F19-; OPG102: K33-; OPG104: P24-; OPG109: K206-; OPG111: F128-; OPG112: S42-; OPG115: S46-; OPG116: K72-; OPG117: K435-, N478-, R551-; OPG118: I80-; OPG122: Y4-; OPG123: K569-; OPG133: K394-; OPG134: E18-, P249-; OPG139: P34-; OPG145: F26-, F269-, K435-; OPG148: I195-, F233-; OPG149: K19-; OPG151: K1034-; OPG164: R90-; OPG165: M239-; OPG172: I192-; OPG175: N96-; OPG176: K178-; OPG178: D13-; OPG180: K223-, K276-; OPG181: F151-; OPG189: L56-, K209-; OPG190: N114-; OPG192: K4-; OPG193: G103-, F263-; OPG198: K231-; OPG208: I96-; OPG209: L130-; OPG210: P727-"}}},{"name":"OP245334","node_attrs":{"div":560,"accession":"OP245334","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPX/PT0081/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-23"},"strain_display":{"value":"Portugal/OP245334/2022-07-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-609T","G610-","T611-","C120237T","G126047A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A196619-","T196620-"],"OPG148":["R21K"]},"labels":{"aa":"OPG148: R21K"}}},{"name":"OP205110","node_attrs":{"div":558,"accession":"OP205110","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV_UK_2022_9000147"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-14"},"strain_display":{"value":"United Kingdom/OP205110/2022-06-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T"]}}},{"name":"OP205091","node_attrs":{"div":558,"accession":"OP205091","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV_UK_2022_9000103"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-13"},"strain_display":{"value":"United Kingdom/OP205091/2022-06-13"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T"]}}},{"name":"OP450985","node_attrs":{"div":558,"accession":"OP450985","author":{"author":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y.","value":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV_USA_2022_TX0019"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP450985/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","A136552-","T136553-","C136554-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-196615A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OQ581847","node_attrs":{"div":571,"accession":"OQ581847","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"country":{"value":"Spain"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0005b/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-01"},"strain_display":{"value":"Spain/OQ581847/2022-07-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A43453G","A66769C","T88735A","G90070A","C101656T","G104325A","C121681T","G127869A","G132490A","T133095A","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T139779C","G140866T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C151204T","T176743A","-179217C","-179218A","-179219T","-179220T"],"OPG063":["L79P"],"OPG085":["V588G"],"OPG109":["E238V"],"OPG110":["D147N"],"OPG123":["A249V"],"OPG150":["G31R"],"OPG160":["S70Y"],"OPG205":["L363*"]},"labels":{"aa":"OPG063: L79P; OPG085: V588G; OPG109: E238V; OPG110: D147N; OPG123: A249V; OPG150: G31R; OPG160: S70Y; OPG205: L363*"}}},{"name":"OR264420","node_attrs":{"div":559,"accession":"OR264420","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"45_B"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-10"},"strain_display":{"value":"Australia/OR264420/2022-07-10"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["G63147A","-179218A","-179219T","-179220T","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"NODE_0000170","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C150831T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-"]}},"children":[{"name":"ON959143","node_attrs":{"div":560,"accession":"ON959143","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O."},"country":{"value":"Finland"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPX-96/Finland/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-16"},"strain_display":{"value":"Finland/ON959143/2022-06-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","C188491T"]}}},{"name":"OP382489","node_attrs":{"div":560,"accession":"OP382489","author":{"author":"Colson,P.","value":"Colson,P."},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"hMPXV-IHU00012"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-19"},"strain_display":{"value":"France/OP382489/2022-07-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G109437A","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G150603-","A150604-","T150605-","A150606-","T150607-","G150608-","A150609-","T150610-","G150611-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T"],"OPG129":["S523L"],"OPG153":["D384-","D385-"]},"labels":{"aa":"OPG129: S523L; OPG153: D384-, D385-"}}},{"name":"OP879740","node_attrs":{"div":559,"accession":"OP879740","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"country":{"value":"USA"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"NJ-MPXV-022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-06"},"strain_display":{"value":"USA/OP879740/2022-07-06"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}}]},{"name":"NODE_0000171","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C33103T","C45605T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG049":["E17K"]},"labels":{"aa":"OPG049: E17K"}},"children":[{"name":"OP215226","node_attrs":{"div":561,"accession":"OP215226","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Germany/2022/RKI241"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP215226/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G47702A"]}}},{"name":"OP594193","node_attrs":{"div":560,"accession":"OP594193","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Germany/2022/RKI429"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP594193/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OQ773504","node_attrs":{"div":560,"accession":"OQ773504","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Germany/2022/ON/RKI885"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773504/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A41660-","A41661-","T41662-","T41663-","T41664-","G41665-","T41666-","T41667-","T41668-","T41669-","A41670-","C41671-","T41672-","C41673-","T41674-","A41675-","T41676-","A41677-","G150551-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG061":["Y70-","R71-","V72-","K73-","Q74-","I75-"]},"labels":{"aa":"OPG061: Y70-, R71-, V72-, K73-, Q74-, I75-"}}}]},{"name":"NODE_0000172","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C20879T","C60094T"],"OPG036":["M62I"],"OPG080":["R642K"]},"labels":{"aa":"OPG036: M62I; OPG080: R642K"}},"children":[{"name":"OP415264","node_attrs":{"div":561,"accession":"OP415264","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPX_Tga3e9_9000325"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415264/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G86904A","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T"]}}},{"name":"OR035722","node_attrs":{"div":561,"accession":"OR035722","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/UZ_REGA_116"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035722/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G149818A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","T196712-","A196713-","T196714-"],"OPG176":["D4N"]},"labels":{"aa":"OPG176: D4N"}}},{"name":"OR464215","node_attrs":{"div":560,"accession":"OR464215","author":{"author":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y.","value":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV_USA_2022_DC0006"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OR464215/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}}]},{"name":"NODE_0000173","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G50672A"],"OPG070":["R28K"]},"labels":{"aa":"OPG070: R28K"}},"children":[{"name":"OP689664","node_attrs":{"div":561,"accession":"OP689664","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Germany/2022/ON/RKI511"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"Germany/OP689664/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C13624T","C43472T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG063":["E73K"]},"labels":{"aa":"OPG063: E73K"}}},{"name":"NODE_0000174","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C49265T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T"]}},"children":[{"name":"OP536764","node_attrs":{"div":561,"accession":"OP536764","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"9000385"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536764/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","C100007T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"],"OPG118":["S521F"]},"labels":{"aa":"OPG118: S521F"}}},{"name":"OP459217","node_attrs":{"div":563,"accession":"OP459217","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"ANT-LDSP-ANT-MPX-23654-O"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-30"},"strain_display":{"value":"Colombia/OP459217/2022-08-30"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C113965T","G150800A","C152191T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG133":["E578K"]},"labels":{"aa":"OPG133: E578K"}}},{"name":"OP623593","node_attrs":{"div":562,"accession":"OP623593","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"country":{"value":"Colombia"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"BOL-UNIMOL-MPX-293264-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-17"},"strain_display":{"value":"Colombia/OP623593/2022-09-17"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["A1701-","C1702-","T1703-","C126654T","G149746A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","T196852-","G196853-","T196854-"],"OPG175":["C102Y"]},"labels":{"aa":"OPG175: C102Y"}}},{"name":"OQ261703","node_attrs":{"div":562,"accession":"OQ261703","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"ANT-LDSP-ANT-MPX-28297C"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-13"},"strain_display":{"value":"Colombia/OQ261703/2022-10-13"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G39515A","T113536C","T196854-","A196855-","A196856-"],"OPG132":["D2G"]},"labels":{"aa":"OPG132: D2G"}}},{"name":"OP959057","node_attrs":{"div":561,"accession":"OP959057","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"country":{"value":"Colombia"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.10"},"strain":{"value":"SUC-UNIMOL-MPX-293401-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-10"},"strain_display":{"value":"Colombia/OP959057/2022-11-10"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["G23118A"]}}}]}]}]},{"name":"NODE_0000175","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G1302A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C182950T"],"OPG001":["L92F"],"OPG210":["S532L"]},"labels":{"aa":"OPG001: L92F; OPG210: S532L","clade":"B.1.12"}},"children":[{"name":"OQ773485","node_attrs":{"div":557,"accession":"OQ773485","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV/Germany/2022/ON/RKI866"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773485/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150563-","T150564-","G150565-","A150566-","T150567-","-179189A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"]}}},{"name":"NODE_0000176","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G78328A","C195908T"],"OPG001_dup":["L92F"]},"labels":{"aa":"OPG001_dup: L92F"}},"children":[{"name":"OP524001","node_attrs":{"div":558,"accession":"OP524001","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV/Germany/2022/RKI399"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP524001/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000177","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C57550T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP415207","node_attrs":{"div":559,"accession":"OP415207","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPX_BhVKjm_9000233"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415207/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OP415206","node_attrs":{"div":559,"accession":"OP415206","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPX_BhVKjm_9000232"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415206/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000178","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A1302G","G111084A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"],"OPG001":["F92L"]},"labels":{"aa":"OPG001: F92L"}},"children":[{"name":"OP013003","node_attrs":{"div":558,"accession":"OP013003","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MpxV/human/CAN/UN-NML-3276/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-31"},"strain_display":{"value":"Canada/OP013003/2022-05-31"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"ON880548","node_attrs":{"div":558,"accession":"ON880548","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MpxV/human/CAN/UN-NML-3448/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-03"},"strain_display":{"value":"Canada/ON880548/2022-06-03"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"OQ121959","node_attrs":{"div":566,"accession":"OQ121959","author":{"author":"Barbian,H.,Green,S.,Kunstman,K.,Araujo Perez,F.,Bobrovska,S.,Hayden,M.,Moore,N.","value":"Barbian,H.,Green,S.,Kunstman,K.,Araujo Perez,F.,Bobrovska,S.,Hayden,M.,Moore,N."},"country":{"value":"USA"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"hMpxV/Human/USA/IL-RIPHL-MPXV_10015/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-18"},"strain_display":{"value":"USA/OQ121959/2022-10-18"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","G4859A","C24077T","C24231T","G67582A","C88319T","G97405A","C101656T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G165506A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C192351T","A196614-"],"OPG015":["S433L"],"OPG015_dup":["S433L"],"OPG085":["S317L"],"OPG109":["A377T"],"OPG117":["E453K"],"OPG190":["E129K"]},"labels":{"aa":"OPG015: S433L; OPG015_dup: S433L; OPG085: S317L; OPG109: A377T; OPG117: E453K; OPG190: E129K"}}},{"name":"NODE_0000179","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G121510A"]}},"children":[{"name":"ON880540","node_attrs":{"div":559,"accession":"ON880540","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MpxV/human/CAN/UN-NML-3342/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-01"},"strain_display":{"value":"Canada/ON880540/2022-06-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"OR759170","node_attrs":{"div":564,"accession":"OR759170","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"hMpxV/Canada/ON-PHOL082/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759170/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","G10060A","G37022A","C132410T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G154793A","C180055T","-196615A"],"OPG055":["S21F"],"OPG181":["D128N"]},"labels":{"aa":"OPG055: S21F; OPG181: D128N"}}}]},{"name":"NODE_0000180","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G98233A","G98455A","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179235C"],"OPG117":["D729N"],"OPG118":["G4K"]},"labels":{"aa":"OPG117: D729N; OPG118: G4K"}},"children":[{"name":"ON880413","node_attrs":{"div":561,"accession":"ON880413","author":{"author":"Coletti,T.M.,Ghilardi,F.,khan,M.J.,Claro,I.M.,Valenca,I.N.,Faria,N.R.,Sabino,E.C.","value":"Coletti,T.M.,Ghilardi,F.,khan,M.J.,Claro,I.M.,Valenca,I.N.,Faria,N.R.,Sabino,E.C."},"country":{"value":"Brazil"},"institution":{"value":"Imperial College London, School of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPX/BR0002/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-14"},"strain_display":{"value":"Brazil/ON880413/2022-06-14"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C76334T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG097":["R181K"]},"labels":{"aa":"OPG097: R181K"}}},{"name":"NODE_0000181","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G98456A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T"]}},"children":[{"name":"OP171925","node_attrs":{"div":563,"accession":"OP171925","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"country":{"value":"USA"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV22/human/USA-NE-75"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-25"},"strain_display":{"value":"USA/OP171925/2022-07-25"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C10484T","A61974G","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"OP270022","node_attrs":{"div":564,"accession":"OP270022","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MpxV/human/CAN/UN-NML-3972/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-04"},"strain_display":{"value":"Canada/OP270022/2022-07-04"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","G3361A","C152970T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G181349A","C193849T"],"OPG003":["S416L"],"OPG003_dup":["S416L"]},"labels":{"aa":"OPG003: S416L; OPG003_dup: S416L"}}},{"name":"OR209309","node_attrs":{"div":564,"accession":"OR209309","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV_USA_2022_TN0019"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR209309/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C93601T","C94418T","T133101-","T133102-","C136029T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["A624V"],"OPG114":["E84K"]},"labels":{"aa":"OPG113: A624V; OPG114: E84K"}}},{"name":"OR464195","node_attrs":{"div":562,"accession":"OR464195","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV_USA_2022_NY0047"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OR464195/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T67849G","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","C179235-"],"OPG085":["N228T"]},"labels":{"aa":"OPG085: N228T"}}},{"name":"NODE_0000182","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G153910A","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-"],"OPG180":["E407K"]},"labels":{"aa":"OPG180: E407K"}},"children":[{"name":"OR759180","node_attrs":{"div":566,"accession":"OR759180","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"hMpxV/Canada/ON-PHOL092/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759180/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","C16209T","C24208T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","C179235-","G182088A","G182189A","A196614-"],"OPG027":["E57K"],"OPG210":["E245K"]},"labels":{"aa":"OPG027: E57K; OPG210: E245K"}}},{"name":"NODE_0000183","node_attrs":{"div":563,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G28483A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP451001","node_attrs":{"div":563,"accession":"OP451001","author":{"author":"Gigante,C.M.,Acheampong,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,McDermott,D.,Li,Y.","value":"Gigante,C.M.,Acheampong,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,McDermott,D.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV_USA_2022_NJ0002"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP451001/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["A173314-","T173315-","A173316-","T173317-","-196615A"]}}},{"name":"OQ427129","node_attrs":{"div":567,"accession":"OQ427129","author":{"author":"Gigante,C.,Murray,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Atkinson,A.,Li,Y.","value":"Gigante,C.,Murray,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Atkinson,A.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV_USA_2022_UT0007"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ427129/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C15582T","C48299T","C122936T","G170349A","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG143":["R127Q"]},"labels":{"aa":"OPG143: R127Q"}}},{"name":"OQ918701","node_attrs":{"div":567,"accession":"OQ918701","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00490/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-10"},"strain_display":{"value":"USA/OQ918701/2023-02-10"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C21910T","G39552A","A57421-","C57422-","A57423-","A57424-","A57425-","A57426-","A57427-","G57428-","G57429-","A57430-","C57431-","A57432-","T57433-","G57434-","T57435-","A57436-","A57437-","A57438-","C57439-","T57440-","T57441-","G132490A","C150443T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T"],"OPG037":["R175K"],"OPG057":["S215F"],"OPG075":["K20-","F21-","T22-","C23-","P24-","F25-","C26-"],"OPG176":["T212I"]},"labels":{"aa":"OPG037: R175K; OPG057: S215F; OPG075: K20-, F21-, T22-, C23-, P24-, F25-, C26-; OPG176: T212I"}}}]}]},{"name":"NODE_0000184","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C24231T","C179226-","C179235-"]}},"children":[{"name":"OP390179","node_attrs":{"div":562,"accession":"OP390179","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"country":{"value":"Colombia"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"BOL-UNIMOL-MPX-293015-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-24"},"strain_display":{"value":"Colombia/OP390179/2022-08-24"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP382485","node_attrs":{"div":563,"accession":"OP382485","author":{"author":"Colson,P.","value":"Colson,P."},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"hMPXV-IHU00008"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"strain_display":{"value":"France/OP382485/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G184227A"],"OPG210":["D958N"]},"labels":{"aa":"OPG210: D958N"}}},{"name":"OR095033","node_attrs":{"div":563,"accession":"OR095033","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV/UZ_REGA_215/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-08"},"strain_display":{"value":"Belgium/OR095033/2022-08-08"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G61102A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG080":["S306F"]},"labels":{"aa":"OPG080: S306F"}}},{"name":"NODE_0000185","node_attrs":{"div":563,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G23457A"],"OPG039":["S221F"]},"labels":{"aa":"OPG039: S221F"}},"children":[{"name":"OP415236","node_attrs":{"div":563,"accession":"OP415236","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPX_ilzdZn_9000269"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415236/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A190409-","A190410-","T190411-","G190412-","G190413-","A190414-","T190415-","T190416-","C190417-","G190418-","C190419-","G190420-","T190421-","A190422-","T190423-","A190424-","G190425-","C190426-"]}}},{"name":"OR264365","node_attrs":{"div":563,"accession":"OR264365","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.12"},"strain":{"value":"12_A"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-18"},"strain_display":{"value":"Australia/OR264365/2022-07-18"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{}}}]}]}]}]}]}]},{"name":"NODE_0000186","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C70780T"]},"labels":{"clade":"B.1.5"}},"children":[{"name":"OP150925","node_attrs":{"div":557,"accession":"OP150925","author":{"author":"Gigante,C.,Xia,D.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y.","value":"Gigante,C.,Xia,D.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV_USA_2022_GA001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/OP150925/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON918656","node_attrs":{"div":561,"accession":"ON918656","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"country":{"value":"Taiwan"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/human/Taiwan/110-231642/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Taiwan/ON918656/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["C28702T","T34793C","T50861C","C51777T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG054":["T402A"],"OPG070":["V91A"],"OPG071":["E888K"]},"labels":{"aa":"OPG054: T402A; OPG070: V91A; OPG071: E888K"}}},{"name":"ON843165","node_attrs":{"div":557,"accession":"ON843165","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"Monkeypox/PT0033/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-24"},"strain_display":{"value":"Portugal/ON843165/2022-05-24"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON780017","node_attrs":{"div":557,"accession":"ON780017","author":{"author":"Gramigna,G.,Giombini,E.,Gruber,C.E.M.,Rueca,M.,Carletti,F.,Cicalini,S.,Lapa,D.,Puro,V.,Marani,A.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Rivano Capparuccia,M.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F.","value":"Gramigna,G.,Giombini,E.,Gruber,C.E.M.,Rueca,M.,Carletti,F.,Cicalini,S.,Lapa,D.,Puro,V.,Marani,A.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Rivano Capparuccia,M.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F."},"country":{"value":"Italy"},"institution":{"value":"INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"INMI-Pt4"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-21"},"strain_display":{"value":"Italy/ON780017/2022-05-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A"]}}},{"name":"OP450990","node_attrs":{"div":560,"accession":"OP450990","author":{"author":"Gigante,C.M.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y.","value":"Gigante,C.M.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV_USA_2022_NV0001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP450990/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G75554A","G147179A","G159373A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG185":["E153K"]},"labels":{"aa":"OPG185: E153K"}}},{"name":"OP414288","node_attrs":{"div":557,"accession":"OP414288","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"Monkeypox/PT0244/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-21"},"strain_display":{"value":"Portugal/OP414288/2022-06-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"]}}},{"name":"OP536756","node_attrs":{"div":559,"accession":"OP536756","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"9000376"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP536756/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C69888T","C150392T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG089":["S8L"],"OPG176":["S195F"]},"labels":{"aa":"OPG089: S8L; OPG176: S195F"}}},{"name":"OP555650","node_attrs":{"div":559,"accession":"OP555650","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"Monkeypox/PT0579/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-10"},"strain_display":{"value":"Portugal/OP555650/2022-09-10"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C41022T","A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159001A"],"OPG060":["R54K"],"OPG153":["D385-"],"OPG185":["D29N"]},"labels":{"aa":"OPG060: R54K; OPG153: D385-; OPG185: D29N"}}},{"name":"OP555598","node_attrs":{"div":565,"accession":"OP555598","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"Monkeypox/PT0527/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-19"},"strain_display":{"value":"Portugal/OP555598/2022-08-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G5876A","C87141T","C126707T","C128030T","C128417T","C133867T","C134247T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C187128T","C191334T"],"OPG015":["S94F"],"OPG015_dup":["S94F"],"OPG148":["S241L"]},"labels":{"aa":"OPG015: S94F; OPG015_dup: S94F; OPG148: S241L"}}},{"name":"OP783902","node_attrs":{"div":557,"accession":"OP783902","author":{"author":"Laubscher,F.,Marques-Melancia,S.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Marques-Melancia,S.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A."},"country":{"value":"Switzerland"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"hMPXV-CH-38347314/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-08"},"strain_display":{"value":"Switzerland/OP783902/2022-06-08"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ274883","node_attrs":{"div":557,"accession":"OQ274883","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/ON/RKI664"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ274883/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OR264397","node_attrs":{"div":561,"accession":"OR264397","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"34_A"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-16"},"strain_display":{"value":"Australia/OR264397/2022-08-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["T606-","C30283T","C37054T","-179197T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","G179589A","G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N"}}},{"name":"ON959175","node_attrs":{"div":557,"accession":"ON959175","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/RKI162"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/ON959175/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP524008","node_attrs":{"div":557,"accession":"OP524008","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/RKI406"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP524008/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000188","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C84063T","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}},"children":[{"name":"OQ547764","node_attrs":{"div":559,"accession":"OQ547764","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/ON/RKI737"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OQ547764/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150563-","G150565-","A150566-","T150567-","C190607T"]}}},{"name":"OQ773477","node_attrs":{"div":558,"accession":"OQ773477","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/ON/RKI858"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773477/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000189","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C160426T"]}},"children":[{"name":"OQ503755","node_attrs":{"div":563,"accession":"OQ503755","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MpxV/human/USA/WA-UW-113327/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"USA/OQ503755/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T10449-","A10450-","G10451-","A10452-","T10453-","G75332A","T124690C","C135762T","C144211T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G185394A"],"OPG095":["R177K"],"OPG210":["E1347K"]},"labels":{"aa":"OPG095: R177K; OPG210: E1347K"}}},{"name":"NODE_0000190","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G111379A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G165326A"],"OPG130":["S175L"],"OPG190":["E69K"]},"labels":{"aa":"OPG130: S175L; OPG190: E69K"}},"children":[{"name":"OP879727","node_attrs":{"div":560,"accession":"OP879727","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"country":{"value":"USA"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"NJ-MPXV-006-rpt1"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP879727/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP650029","node_attrs":{"div":563,"accession":"OP650029","author":{"author":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T.","value":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T."},"country":{"value":"USA"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV22/human/USA-OK-81"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-26"},"strain_display":{"value":"USA/OP650029/2022-07-26"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G22207A","C82187T","C120671T","T136555-","G136558C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG037":["S76F"]},"labels":{"aa":"OPG037: S76F"}}},{"name":"OQ721933","node_attrs":{"div":561,"accession":"OQ721933","author":{"author":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y.","value":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV_USA_2022_OH0005"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721933/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G48045A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","G173318-","G173319-","G173320-","C173321-","A173322-","A173323-","A173324-","A173325-","C173326-","A173327-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"]}}}]}]},{"name":"NODE_0000191","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C44333T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG064":["M522I"]},"labels":{"aa":"OPG064: M522I"}},"children":[{"name":"OP415189","node_attrs":{"div":558,"accession":"OP415189","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPX_luLfgA_9000208"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415189/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OR035675","node_attrs":{"div":559,"accession":"OR035675","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/UZ_REGA_69"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-30"},"strain_display":{"value":"Belgium/OR035675/2022-06-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G161488A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OR035702","node_attrs":{"div":562,"accession":"OR035702","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/UZ_REGA_96"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Belgium/OR035702/2022-05-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C29315T","C60396T","G149807A","C161572T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG046":["D139N"]},"labels":{"aa":"OPG046: D139N"}}},{"name":"OR449644","node_attrs":{"div":562,"accession":"OR449644","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/ON/RKI930"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449644/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G24983A","G46956A","G135180A","G143432A","G150551-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG066":["P158L"],"OPG164":["D219N"],"OPG193":["F263-"]},"labels":{"aa":"OPG066: P158L; OPG164: D219N; OPG193: F263-"}}},{"name":"NODE_0000192","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G93512T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG113":["K594N"]},"labels":{"aa":"OPG113: K594N"}},"children":[{"name":"OP358276","node_attrs":{"div":562,"accession":"OP358276","author":{"author":"Tramuto,F.","value":"Tramuto,F."},"country":{"value":"Italy"},"institution":{"value":"University of Palermo, Department of Health Promotion Sciences Maternal and Infant Care, Internal Medicine and Medical Specialties \"G. D'Alessandro\"\"\""},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"SIC-AOUP-UNIPA_VL_9aug"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-09"},"strain_display":{"value":"Italy/OP358276/2022-08-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C33103T","C114490T","C133295T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-"],"OPG049":["E17K"],"OPG133":["D403N"]},"labels":{"aa":"OPG049: E17K; OPG133: D403N"}}},{"name":"OR264417","node_attrs":{"div":560,"accession":"OR264417","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.5"},"strain":{"value":"43_A"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-22"},"strain_display":{"value":"Australia/OR264417/2022-06-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["G2898A","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","C194312T"]}}}]}]}]},{"name":"NODE_0000193","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N","clade":"B.1.2"}},"children":[{"name":"OP150927","node_attrs":{"div":557,"accession":"OP150927","author":{"author":"Gigante,C.,Pavlick,J.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y.","value":"Gigante,C.,Pavlick,J.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_USA_2022_WA001"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/OP150927/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON929079","node_attrs":{"div":557,"accession":"ON929079","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/RKI124"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/ON929079/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-"]}}},{"name":"OP205082","node_attrs":{"div":558,"accession":"OP205082","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_UK_2022_9000079"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-15"},"strain_display":{"value":"United Kingdom/OP205082/2022-06-15"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C123899T","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG144":["D12N"]},"labels":{"aa":"OPG144: D12N"}}},{"name":"OP415193","node_attrs":{"div":557,"accession":"OP415193","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPX_gOirGi_9000215"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415193/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ274892","node_attrs":{"div":557,"accession":"OQ274892","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/ON/RKI673"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ274892/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-","C179172-"]}}},{"name":"OQ054238","node_attrs":{"div":560,"accession":"OQ054238","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_USA_2022_TX0016"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ054238/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C15575T","G16220A","G48662C","T173270-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A"],"OPG027":["S53L"],"OPG068":["M154I"]},"labels":{"aa":"OPG027: S53L; OPG068: M154I"}}},{"name":"NODE_0000194","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C20992T","G143789A"],"OPG036":["D25N"],"OPG165":["D92N"]},"labels":{"aa":"OPG036: D25N; OPG165: D92N"}},"children":[{"name":"NODE_0000195","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C29229T","C57492T","G73939A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG045":["D12N"],"OPG075":["E3K"],"OPG094":["D54N"]},"labels":{"aa":"OPG045: D12N; OPG075: E3K; OPG094: D54N"}},"children":[{"name":"OP536807","node_attrs":{"div":565,"accession":"OP536807","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"9000438"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536807/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G10475A","G23462A","C171808T","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG199":["S274L"]},"labels":{"aa":"OPG199: S274L"}}},{"name":"OP555557","node_attrs":{"div":562,"accession":"OP555557","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"Monkeypox/PT0478/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-08"},"strain_display":{"value":"Portugal/OP555557/2022-08-08"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C179172-"]}}}]},{"name":"NODE_0000196","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C147168T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG171":["L61F"]},"labels":{"aa":"OPG171: L61F"}},"children":[{"name":"OP279039","node_attrs":{"div":560,"accession":"OP279039","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/CAN/UN-NML-4117/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-28"},"strain_display":{"value":"Canada/OP279039/2022-06-28"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264413","node_attrs":{"div":560,"accession":"OR264413","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"42_B"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-22"},"strain_display":{"value":"Australia/OR264413/2022-06-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"]}}},{"name":"OR463713","node_attrs":{"div":561,"accession":"OR463713","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/ON/RKI759"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OR463713/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G66015A","G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","A181253-"],"OPG084":["D432N"]},"labels":{"aa":"OPG084: D432N"}}}]}]},{"name":"NODE_0000197","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188391T"]}},"children":[{"name":"OP215262","node_attrs":{"div":559,"accession":"OP215262","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/RKI238"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP215262/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G182303A"]}}},{"name":"OP205083","node_attrs":{"div":558,"accession":"OP205083","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_UK_2022_9000092"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-25"},"strain_display":{"value":"United Kingdom/OP205083/2022-05-25"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OP450991","node_attrs":{"div":559,"accession":"OP450991","author":{"author":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y.","value":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_USA_2022_TX0018"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP450991/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","G45781A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","-196615A"],"OPG064":["H40Y"]},"labels":{"aa":"OPG064: H40Y"}}},{"name":"OP536791","node_attrs":{"div":563,"accession":"OP536791","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"9000417"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP536791/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","G23288A","C36267T","G40863A","C85322T","G92048A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"],"OPG055":["D273N"],"OPG060":["S107L"]},"labels":{"aa":"OPG055: D273N; OPG060: S107L"}}},{"name":"OP615326","node_attrs":{"div":561,"accession":"OP615326","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/ON/RKI446"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP615326/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C101983T","C141757T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C160426T","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG121":["S65L"]},"labels":{"aa":"OPG121: S65L"}}},{"name":"OP605583","node_attrs":{"div":563,"accession":"OP605583","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"Slovenia-MPXV-42-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Slovenia/OP605583/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A161-","-607T","C17614A","C27187T","G111484A","G147305A","C159401A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG030":["V74L"],"OPG043":["D257N"],"OPG130":["T140I"],"OPG185":["S162Y"]},"labels":{"aa":"OPG030: V74L; OPG043: D257N; OPG130: T140I; OPG185: S162Y"}}},{"name":"OQ320468","node_attrs":{"div":559,"accession":"OQ320468","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_USA_2022_TN0014"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ320468/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","C150028T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A"],"OPG176":["R74C"]},"labels":{"aa":"OPG176: R74C"}}},{"name":"OR086973","node_attrs":{"div":559,"accession":"OR086973","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/UZ_REGA_164/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR086973/2022-07-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G135633A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"NODE_0000198","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T157527C","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}},"children":[{"name":"ON853649","node_attrs":{"div":563,"accession":"ON853649","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/RKI068"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/ON853649/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G22425A","G22971A","C26694A","C77829T"],"OPG042":["W135L"]},"labels":{"aa":"OPG042: W135L"}}},{"name":"OP555483","node_attrs":{"div":560,"accession":"OP555483","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"Monkeypox/PT0387/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-12"},"strain_display":{"value":"Portugal/OP555483/2022-07-12"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G154098A"]}}}]},{"name":"NODE_0000199","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T26669C","G96073A","G115235A","C125294T"],"OPG117":["D9N"]},"labels":{"aa":"OPG117: D9N"}},"children":[{"name":"OQ159027","node_attrs":{"div":564,"accession":"OQ159027","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/RKI632"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"Germany/OQ159027/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G77052A","C135868T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP959060","node_attrs":{"div":562,"accession":"OP959060","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"country":{"value":"Colombia"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"BOL-UNIMOL-MPX-293428-L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-29"},"strain_display":{"value":"Colombia/OP959060/2022-10-29"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000200","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G8638A","C21548T","C188236T","C188339T"],"OPG037":["D296N"]},"labels":{"aa":"OPG037: D296N"}},"children":[{"name":"OQ503753","node_attrs":{"div":562,"accession":"OQ503753","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/USA/WA-UW-110466/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"USA/OQ503753/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-196615A"]}}},{"name":"NODE_0000201","node_attrs":{"div":564,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C47820T","C68218T"],"OPG085":["R105Q"]},"labels":{"aa":"OPG085: R105Q"}},"children":[{"name":"OQ503756","node_attrs":{"div":566,"accession":"OQ503756","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/USA/WA-UW-126801/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OQ503756/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","G12239A","G12488A","-196615A"],"OPG023":["S138L","S221F"]},"labels":{"aa":"OPG023: S138L, S221F"}}},{"name":"OR427343","node_attrs":{"div":565,"accession":"OR427343","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/USA/WA-UW-038917/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-XX"},"strain_display":{"value":"USA/OR427343/2023-03-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G100939A"]}}},{"name":"OR427340","node_attrs":{"div":564,"accession":"OR427340","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/USA/WA-UW-028603/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-XX"},"strain_display":{"value":"USA/OR427340/2023-02-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{}}},{"name":"OR427336","node_attrs":{"div":565,"accession":"OR427336","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/USA/WA-UW-019613/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-XX"},"strain_display":{"value":"USA/OR427336/2023-01-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","C165586T","-196615A"]}}},{"name":"OR499953","node_attrs":{"div":565,"accession":"OR499953","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00496/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-04-26"},"strain_display":{"value":"USA/OR499953/2023-04-26"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C102741T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG122":["S105L"]},"labels":{"aa":"OPG122: S105L"}}}]}]}]}]},{"name":"NODE_0000202","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G74360A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C"],"OPG094":["R194H"]},"labels":{"aa":"OPG094: R194H","clade":"B.1.1"}},"children":[{"name":"ON792321","node_attrs":{"div":557,"accession":"ON792321","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"country":{"value":"Switzerland"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba6450e/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-02"},"strain_display":{"value":"Switzerland/ON792321/2022-06-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","A19360-","T19361-","C19362-","A19363-","T19364-","T19365-","A43653-","T43654-","T43655-","A49176-","A49177-","T49178-","T49179-","T49180-","T49181-","A49182-","T49183-","T49184-","A49185-","A49186-","C49187-","G49188-","G49189-","T49190-","A49191-","A49192-","T49193-","A79063-","A79064-","T79065-","T79066-","T79067-","T79068-","A79069-","A79070-","T79071-","A79072-","T79073-","A79074-","A79075-","T79076-","A79077-","C79078-","T79079-","T79080-","A79081-","A79082-","A79083-","A79084-","A79085-","T79086-","G79087-","G79088-","A79089-","T79090-","G79091-","T79092-","T79093-","G79094-","T79095-","G79096-","T79097-","C79098-","G79099-","T79100-","T79101-","A79102-","A152691-","A152692-","T152693-","G152694-","A152695-","C152696-","G152697-","T152698-","A175944-","T175945-","A175946-","T175947-","C175948-","A175949-","A175950-","C179127A","C179136T","T179138A","T179148-","T179157-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","C179190T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T180493-","A180494-","T180495-","C180496-","A180497-","T180498-","T180499-"],"OPG063":["D50-"],"OPG068":["N329-","G330-","N331-","T332-","F333-","I334-"],"OPG205":["I97-","S98-","I99-"]},"labels":{"aa":"OPG063: D50-; OPG068: N329-, G330-, N331-, T332-, F333-, I334-; OPG205: I97-, S98-, I99-"}}},{"name":"ON694329","node_attrs":{"div":557,"accession":"ON694329","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/RKI025"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/ON694329/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-","A192490-","A192491-","G192492-","T192493-","T192494-","A192495-","G192496-","T192497-","T192498-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP339846","node_attrs":{"div":559,"accession":"OP339846","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/RKI289"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP339846/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168264T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","G187135A"],"OPG195":["S12F"]},"labels":{"aa":"OPG195: S12F"}}},{"name":"OP204857","node_attrs":{"div":559,"accession":"OP204857","author":{"author":"Rhie,G.-E.","value":"Rhie,G.-E."},"country":{"value":"South Korea"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV-ROK-P1-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"South Korea/OP204857/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["C786T","C71728T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G173429A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG091":["A120V"]},"labels":{"aa":"OPG091: A120V"}}},{"name":"OP382488","node_attrs":{"div":558,"accession":"OP382488","author":{"author":"Colson,P.","value":"Colson,P."},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMPXV-IHU00011"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-19"},"strain_display":{"value":"France/OP382488/2022-07-19"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C153387T","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP837475","node_attrs":{"div":559,"accession":"OP837475","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"DC_INS_MPX_1009_L"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-19"},"strain_display":{"value":"Colombia/OP837475/2022-09-19"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C17764T","G54336A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG030":["D24N"],"OPG071":["P35S"]},"labels":{"aa":"OPG030: D24N; OPG071: P35S"}}},{"name":"OP752114","node_attrs":{"div":557,"accession":"OP752114","author":{"author":"Gigante,C.M.,Cogswell,K.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Morrison,S.S.,Desch,M.,Knipe,K.,Weigand,M.R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Grenz,L.,Li,Y.","value":"Gigante,C.M.,Cogswell,K.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Morrison,S.S.,Desch,M.,Knipe,K.,Weigand,M.R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Grenz,L.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV_USA_2022_OR0003"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP752114/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OQ547755","node_attrs":{"div":557,"accession":"OQ547755","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI728"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ547755/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150563-","T150564-","G150565-","A150566-","T150567-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179190-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","G181052-"],"OPG209":["G179-"]},"labels":{"aa":"OPG209: G179-"}}},{"name":"OR449656","node_attrs":{"div":557,"accession":"OR449656","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI942"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449656/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"OR427334","node_attrs":{"div":565,"accession":"OR427334","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MpxV/human/USA/WA-UW-121247/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR427334/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","C11810T","G52232A","G59218A","C63120T","G75522A","C119838T","C159899T","G160110A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG023":["R364K"],"OPG071":["S736L"],"OPG079":["S135L"]},"labels":{"aa":"OPG023: R364K; OPG071: S736L; OPG079: S135L"}}},{"name":"OR264400","node_attrs":{"div":559,"accession":"OR264400","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"36_B"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-15"},"strain_display":{"value":"Australia/OR264400/2022-08-15"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["T76084-","T76085-","G118500A","G160406A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG136":["T363M"]},"labels":{"aa":"OPG136: T363M"}}},{"name":"OR264368","node_attrs":{"div":558,"accession":"OR264368","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"15_B"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-22"},"strain_display":{"value":"Australia/OR264368/2022-08-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","T76084-","T76085-","T80846-","T80847-","T121121-","T133094-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","G183484A"],"OPG044":["K147-"],"OPG210":["R710K"]},"labels":{"aa":"OPG044: K147-; OPG210: R710K"}}},{"name":"OR095036","node_attrs":{"div":560,"accession":"OR095036","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/UZ_REGA_218/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-08"},"strain_display":{"value":"Belgium/OR095036/2022-08-08"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C25828T","G107496A","G109463A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG042":["E424K"]},"labels":{"aa":"OPG042: E424K"}}},{"name":"OR500078","node_attrs":{"div":557,"accession":"OR500078","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"country":{"value":"Romania"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Romania/B-8/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-29"},"strain_display":{"value":"Romania/OR500078/2022-06-29"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T92388-","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["F220-"]},"labels":{"aa":"OPG113: F220-"}}},{"name":"OR463727","node_attrs":{"div":559,"accession":"OR463727","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI784"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OR463727/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C14799T","G69951A","G150551-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","A181253-"],"OPG025":["D157N"],"OPG089":["G29E"]},"labels":{"aa":"OPG025: D157N; OPG089: G29E"}}},{"name":"NODE_0000203","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C17048T","G93828A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177009A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"],"OPG029":["D8N"],"OPG113":["E700K"],"OPG205":["E452K"]},"labels":{"aa":"OPG029: D8N; OPG113: E700K; OPG205: E452K"}},"children":[{"name":"OQ159028","node_attrs":{"div":561,"accession":"OQ159028","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/RKI633"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"Germany/OQ159028/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C41131T"],"OPG060":["E18K"]},"labels":{"aa":"OPG060: E18K"}}},{"name":"OQ735077","node_attrs":{"div":567,"accession":"OQ735077","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/PT0626/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-21"},"strain_display":{"value":"Portugal/OQ735077/2023-03-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-609T","A615-","C616-","C10929T","C22179T","G39515A","G77076A","G129659A","C129949T","G139167A","C196638-","T196639-"],"OPG023":["E658K"],"OPG151":["E246K"]},"labels":{"aa":"OPG023: E658K; OPG151: E246K"}}}]},{"name":"NODE_0000204","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C29887T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}},"children":[{"name":"OR264437","node_attrs":{"div":558,"accession":"OR264437","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"56_C"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-06"},"strain_display":{"value":"Australia/OR264437/2022-09-06"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-"],"OPG044":["K147-"]},"labels":{"aa":"OPG044: K147-"}}},{"name":"OR264424","node_attrs":{"div":558,"accession":"OR264424","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"47_A"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-13"},"strain_display":{"value":"Australia/OR264424/2022-07-13"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000205","node_attrs":{"div":564,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C42674T","C46672T","C56805T","C72314T","C103216T","C127628T","T152686-","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C180857T"],"OPG063":["E339K"],"OPG066":["E253K"],"OPG074":["M107I"],"OPG092":["D212N"],"OPG123":["V619I"],"OPG149":["P145S"]},"labels":{"aa":"OPG063: E339K; OPG066: E253K; OPG074: M107I; OPG092: D212N; OPG123: V619I; OPG149: P145S"}},"children":[{"name":"OR500085","node_attrs":{"div":564,"accession":"OR500085","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"country":{"value":"Romania"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Romania/B-35_R2/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-26"},"strain_display":{"value":"Romania/OR500085/2023-01-26"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179199C","-179200A","-179201T"]}}},{"name":"OR500086","node_attrs":{"div":566,"accession":"OR500086","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"country":{"value":"Romania"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Romania/B-35_R3/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-15"},"strain_display":{"value":"Romania/OR500086/2023-02-15"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G169748A","C179190T","T179192A","T179193A","A179198G","A185438C","C185439A"]}}}]},{"name":"NODE_0000206","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C11401T","T133102-","A136552-","T136553-","C136554-","C179190-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}},"children":[{"name":"OQ427112","node_attrs":{"div":560,"accession":"OQ427112","author":{"author":"Gigante,C.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y.","value":"Gigante,C.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV_USA_2022_NV0005"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ427112/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C72269T","G140194A","G158318A"],"OPG092":["D227N"],"OPG159":["D143N"],"OPG160":["S294L"]},"labels":{"aa":"OPG092: D227N; OPG159: D143N; OPG160: S294L"}}},{"name":"OQ721942","node_attrs":{"div":560,"accession":"OQ721942","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV_USA_2022_TX0051"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721942/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G23673A","G50121A","-133102T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"],"OPG039":["S149L"],"OPG069":["E46K"]},"labels":{"aa":"OPG039: S149L; OPG069: E46K"}}},{"name":"OR464214","node_attrs":{"div":558,"accession":"OR464214","author":{"author":"Gigante,C.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y.","value":"Gigante,C.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV_USA_2022_CA0008"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OR464214/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-"]}}}]},{"name":"NODE_0000207","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155698A"]}},"children":[{"name":"OR759194","node_attrs":{"div":567,"accession":"OR759194","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Canada/ON-PHOL106/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-01"},"strain_display":{"value":"Canada/OR759194/2022-07-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C7235T","C32798T","C55589T","C61706T","G115768A","T120124-","T120125-","A120126-","G120127-","A120128-","T120129-","A120130-","A120131-","T120132-","G127806A","G159118A","G162726A","C177833T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"],"OPG074":["E513K"],"OPG080":["V105I"],"OPG134":["D7N"],"OPG137":["L175-","D176-","N177-"],"OPG150":["E10K"],"OPG185":["D68N"]},"labels":{"aa":"OPG074: E513K; OPG080: V105I; OPG134: D7N; OPG137: L175-, D176-, N177-; OPG150: E10K; OPG185: D68N"}}},{"name":"NODE_0000208","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G161575A"]}},"children":[{"name":"OP245330","node_attrs":{"div":559,"accession":"OP245330","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPX/PT0076/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-23"},"strain_display":{"value":"Portugal/OP245330/2022-07-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"]}}},{"name":"OR459775","node_attrs":{"div":561,"accession":"OR459775","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"country":{"value":"South Korea"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV-ROK-P002-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-02"},"strain_display":{"value":"South Korea/OR459775/2022-09-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["G14640A","C108843T","G136558C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG025":["H210Y"],"OPG153":["I370M"]},"labels":{"aa":"OPG025: H210Y; OPG153: I370M"}}},{"name":"OR086942","node_attrs":{"div":559,"accession":"OR086942","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/UZ_REGA_133/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"strain_display":{"value":"Belgium/OR086942/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T133102-","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196748-","T196749-","C196750-"]}}}]}]},{"name":"NODE_0000209","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C22739T","C179190-"],"OPG038":["E141K"]},"labels":{"aa":"OPG038: E141K"}},"children":[{"name":"OP019276","node_attrs":{"div":558,"accession":"OP019276","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"country":{"value":"Austria"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMPXV/Austria/MUW1527495/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-21"},"strain_display":{"value":"Austria/OP019276/2022-06-21"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON808413","node_attrs":{"div":558,"accession":"ON808413","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"country":{"value":"United Kingdom"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"CVR_MPXV1a"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-15"},"strain_display":{"value":"United Kingdom/ON808413/2022-05-15"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP415188","node_attrs":{"div":559,"accession":"OP415188","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPX_dDDHx_9000207"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"United Kingdom/OP415188/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T33222-","A33223-","T33224-","T33225-","C33226-","T33227-","C33228-","A33229-","T33230-","T33231-","G33232-","C33233-","T33234-","T33235-","C144199T","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG050":["S59-","N60-","E61-","N62-","I63-"]},"labels":{"aa":"OPG050: S59-, N60-, E61-, N62-, I63-"}}},{"name":"OP523996","node_attrs":{"div":558,"accession":"OP523996","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/RKI397"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP523996/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-"]}}},{"name":"OP752118","node_attrs":{"div":561,"accession":"OP752118","author":{"author":"Gigante,C.M.,Epie,N.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Morrison,S.S.,Desch,M.,Knipe,K.,Weigand,M.R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Perez,T.,Li,Y.","value":"Gigante,C.M.,Epie,N.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Morrison,S.S.,Desch,M.,Knipe,K.,Weigand,M.R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Perez,T.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV_USA_2022_SC0005"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OP752118/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T4775-","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","G70775A","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C186124T","C189996T","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"],"OPG089":["D304N"],"OPG210":["S1590F"]},"labels":{"aa":"OPG089: D304N; OPG210: S1590F"}}},{"name":"NODE_0000210","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C22740T","C38937T"],"OPG056":["R33Q"]},"labels":{"aa":"OPG056: R33Q"}},"children":[{"name":"OP415276","node_attrs":{"div":561,"accession":"OP415276","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPX_KV9qz9_9000349"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415276/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C67659T","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG085":["M291I"]},"labels":{"aa":"OPG085: M291I"}}},{"name":"NODE_0000211","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G74362A","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","T136555-","A136556-","T136557-","G136558-","A136559-","T136560-","A136561-","T136562-","C136563-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C177240T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-"],"OPG094":["A195T"],"OPG153":["I370-","I371-","D372-","D373-","D374-","D375-","D376-","D377-"],"OPG205":["Q529*"]},"labels":{"aa":"OPG094: A195T; OPG153: I370-, I371-, D372-, D373-, D374-, D375-, D376-, D377-; OPG205: Q529*"}},"children":[{"name":"OP555641","node_attrs":{"div":562,"accession":"OP555641","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"Monkeypox/PT0570/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-02"},"strain_display":{"value":"Portugal/OP555641/2022-09-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OP555627","node_attrs":{"div":563,"accession":"OP555627","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.1"},"strain":{"value":"Monkeypox/PT0556/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-30"},"strain_display":{"value":"Portugal/OP555627/2022-08-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","G157775A","-196615A"]}}}]}]}]}]},{"name":"NODE_0000212","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C25644T"]},"labels":{"clade":"B.1.7"}},"children":[{"name":"ON843170","node_attrs":{"div":557,"accession":"ON843170","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"Monkeypox/PT0031/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-26"},"strain_display":{"value":"Portugal/ON843170/2022-05-26"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP205081","node_attrs":{"div":557,"accession":"OP205081","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_UK_2022_9000078"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-14"},"strain_display":{"value":"United Kingdom/OP205081/2022-06-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP413716","node_attrs":{"div":559,"accession":"OP413716","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"9000351"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP413716/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C31006T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C182707T"],"OPG210":["S451F"]},"labels":{"aa":"OPG210: S451F"}}},{"name":"OP615340","node_attrs":{"div":561,"accession":"OP615340","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/ON/RKI458"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP615340/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G23359A","C40251T","C114955T","C116175T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG039":["L254F"],"OPG058":["D62N"],"OPG133":["D248N"]},"labels":{"aa":"OPG039: L254F; OPG058: D62N; OPG133: D248N"}}},{"name":"OP597782","node_attrs":{"div":560,"accession":"OP597782","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"country":{"value":"USA"},"institution":{"value":"Minnesota Department of Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MN-MDH-MPXV_0008"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"strain_display":{"value":"USA/OP597782/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G74619A","G83118A","T87356C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG105":["A665T"],"OPG109":["K698E"]},"labels":{"aa":"OPG105: A665T; OPG109: K698E"}}},{"name":"OQ320507","node_attrs":{"div":560,"accession":"OQ320507","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_USA_2022_TN0013"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ320507/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","C1735T","C31714T","T149447C","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G195475A","-196615A"],"OPG048":["G151S"]},"labels":{"aa":"OPG048: G151S"}}},{"name":"OQ547747","node_attrs":{"div":557,"accession":"OQ547747","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/ON/RKI720"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ547747/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G150551-","G150568-","A150569-","T150570-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OR759218","node_attrs":{"div":559,"accession":"OR759218","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"hMpxV/Canada/ON-PHOL130/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759218/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C81095T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C172410T"]}}},{"name":"NODE_0000213","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G63147A"]}},"children":[{"name":"ON927248","node_attrs":{"div":562,"accession":"ON927248","author":{"author":"Chan,W.Y.,Mtshali,P.S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J.","value":"Chan,W.Y.,Mtshali,P.S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J."},"country":{"value":"South Africa"},"institution":{"value":"National Institute for Communicable Disease, Sequencing core facility"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"NICD-SVPL232"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-24"},"strain_display":{"value":"South Africa/ON927248/2022-06-24"},"clade_membership":{"value":"IIb"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["G10224A","G129761A","T143625A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C177847T","A196601C","-196615A"],"OPG021":["R213Q"],"OPG151":["D280N"],"OPG165":["I37N"],"OPG205":["S731L"]},"labels":{"aa":"OPG021: R213Q; OPG151: D280N; OPG165: I37N; OPG205: S731L"}}},{"name":"OR264426","node_attrs":{"div":558,"accession":"OR264426","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"48_C"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Australia/OR264426/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}}]},{"name":"NODE_0000214","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G120241A","-179194A","-179195T","T179244-","T179247-","T179248-","A179249-","T179250-","T179251-","T179253-","T179254-","T179255-","T179258-","T179260-","A179261-","T179262-","A179266-","T179267-","A181253-"],"OPG137":["D214N"]},"labels":{"aa":"OPG137: D214N"}},"children":[{"name":"ON911481","node_attrs":{"div":561,"accession":"ON911481","author":{"author":"Galan-Huerta,K.A.,Paz-Infanzon,M.,Ruiz-Higareda,A.F.,Nuzzolo-Shihadeh,L.,Camacho-Ortiz,A.,Bocanegra-Ibarias,P.,Rivas-Estilla,A.M.,Zacarias-Villarreal,D.,Yamallel-Ortega,L.A.,Guerrero-Putz,M.D.,Ocampo-Candiani,J.","value":"Galan-Huerta,K.A.,Paz-Infanzon,M.,Ruiz-Higareda,A.F.,Nuzzolo-Shihadeh,L.,Camacho-Ortiz,A.,Bocanegra-Ibarias,P.,Rivas-Estilla,A.M.,Zacarias-Villarreal,D.,Yamallel-Ortega,L.A.,Guerrero-Putz,M.D.,Ocampo-Candiani,J."},"country":{"value":"Mexico"},"institution":{"value":"Universidad Autonoma de Nuevo Leon - Facultad de Medicina, Centro de Investigacion e Innovacion en Virologia Medica"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"Monkeypox/MX-UANL001/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-28"},"strain_display":{"value":"Mexico/ON911481/2022-06-28"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","G57088A","C127530T","T133098-","T133099-","T133100-","T133101-","T133102-","T168120C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-179244T","-179247T","-179248T","-179249A","-179250T","-179251T","-179253T","-179254T","-179255T","-179258T","-179260T","-179261A","-179262T","-179266A","-179267T","-181253A","-196615A","-196616A","-196617A"],"OPG074":["S13L"],"OPG149":["S112L"],"OPG193":["F263L"]},"labels":{"aa":"OPG074: S13L; OPG149: S112L; OPG193: F263L"}}},{"name":"OR463720","node_attrs":{"div":558,"accession":"OR463720","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/ON/RKI779"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OR463720/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179245-","G179246-","G179252-","G179256-","G179257-","C179259-","G179263-","C179264-","C179265-"]}}}]},{"name":"NODE_0000215","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C66249T","C88644A","C104134T","C112638T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG109":["K268N"],"OPG123":["A313T"]},"labels":{"aa":"OPG109: K268N; OPG123: A313T"}},"children":[{"name":"OP263628","node_attrs":{"div":561,"accession":"OP263628","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/RKI274"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP263628/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OP536778","node_attrs":{"div":563,"accession":"OP536778","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"9000400"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536778/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","G69081A","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G186489A","A196614-"],"OPG153":["D385-"],"OPG210":["D1712N"]},"labels":{"aa":"OPG153: D385-; OPG210: D1712N"}}}]},{"name":"NODE_0000216","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C14077T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP205084","node_attrs":{"div":560,"accession":"OP205084","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_UK_2022_9000093"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-30"},"strain_display":{"value":"United Kingdom/OP205084/2022-05-30"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C4529T","G155585A","G192681A"],"OPG003":["D27N"],"OPG003_dup":["D27N"]},"labels":{"aa":"OPG003: D27N; OPG003_dup: D27N"}}},{"name":"NODE_0000217","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G105860A"]}},"children":[{"name":"OP415197","node_attrs":{"div":561,"accession":"OP415197","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPX_2v76E1_9000221"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415197/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G41557A","G91376A"],"OPG061":["P110S"],"OPG112":["D44N"]},"labels":{"aa":"OPG061: P110S; OPG112: D44N"}}},{"name":"OR095063","node_attrs":{"div":559,"accession":"OR095063","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/UZ_REGA_245/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-16"},"strain_display":{"value":"Belgium/OR095063/2022-08-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}}]}]},{"name":"NODE_0000218","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C148771T"],"OPG174":["D209N"]},"labels":{"aa":"OPG174: D209N"}},"children":[{"name":"OR449631","node_attrs":{"div":560,"accession":"OR449631","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/ON/RKI917"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449631/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G69840A","C99542T","G150551-","A150563-","T150564-","G150565-","A150566-","T150567-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG118":["S366F"],"OPG193":["F263-"]},"labels":{"aa":"OPG118: S366F; OPG193: F263-"}}},{"name":"OR464198","node_attrs":{"div":559,"accession":"OR464198","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_USA_2022_NY0050"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OR464198/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C31881T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A"],"OPG048":["G95E"]},"labels":{"aa":"OPG048: G95E"}}},{"name":"NODE_0000219","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G114316A","G152437A"],"OPG133":["H461Y"]},"labels":{"aa":"OPG133: H461Y"}},"children":[{"name":"OQ159026","node_attrs":{"div":561,"accession":"OQ159026","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/RKI631"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"Germany/OQ159026/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G150547A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G187677A"]}}},{"name":"OQ627928","node_attrs":{"div":560,"accession":"OQ627928","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"country":{"value":"Italy"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"INMI-19442022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-14"},"strain_display":{"value":"Italy/OQ627928/2022-09-14"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-608T","G610-","T611-","A612-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}}]}]},{"name":"NODE_0000220","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G42504A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}},"children":[{"name":"OP324545","node_attrs":{"div":562,"accession":"OP324545","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"Monkeypox/PT0237/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-22"},"strain_display":{"value":"Portugal/OP324545/2022-06-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C5292T","G74267A","C115870T","A161784T","G191918A"],"OPG015":["D289N"],"OPG015_dup":["D289N"],"OPG094":["R163Q"]},"labels":{"aa":"OPG015: D289N; OPG015_dup: D289N; OPG094: R163Q"}}},{"name":"OP245307","node_attrs":{"div":560,"accession":"OP245307","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPX/PT0050/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Portugal/OP245307/2022-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A796-","C797-","C134850T","C159741T","C196739-","T196740-"]}}},{"name":"OP204840","node_attrs":{"div":559,"accession":"OP204840","author":{"author":"Seang,S.,Burrel,S.,Todesco,E.,Leducq,V.,Monsel,G.,Le Pluart,D.,Cordevant,C.,Pourcher,V.,Palich,R.,Charpentier,C.","value":"Seang,S.,Burrel,S.,Todesco,E.,Leducq,V.,Monsel,G.,Le Pluart,D.,Cordevant,C.,Pourcher,V.,Palich,R.,Charpentier,C."},"country":{"value":"France"},"institution":{"value":"APHP Pitie Salpetriere SU, Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"PatientMPXV"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-10"},"strain_display":{"value":"France/OP204840/2022-06-10"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G163250A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196612-","A196613-","A196614-"]}}},{"name":"OP415190","node_attrs":{"div":561,"accession":"OP415190","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPX_KJ3uDD_9000210"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"United Kingdom/OP415190/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C36834T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G168034A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C181209T","A181253-"],"OPG055":["E84K"],"OPG193":["R234K"]},"labels":{"aa":"OPG055: E84K; OPG193: R234K"}}},{"name":"OP555475","node_attrs":{"div":558,"accession":"OP555475","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"Monkeypox/PT0379/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-06"},"strain_display":{"value":"Portugal/OP555475/2022-07-06"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000221","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C57173T"]}},"children":[{"name":"OP727822","node_attrs":{"div":565,"accession":"OP727822","author":{"author":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K.","value":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K."},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"PrEV_case_2"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-02"},"strain_display":{"value":"Belgium/OP727822/2022-10-02"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T604-","T605-","T606-","C11401T","C33964T","C36267T","G110285A","T133102-","C144366T","A174924T","G180608A","A188351-","G195316A"],"OPG052":["R11Q"],"OPG055":["D273N"],"OPG209":["E31K"]},"labels":{"aa":"OPG052: R11Q; OPG055: D273N; OPG209: E31K"}}},{"name":"NODE_0000222","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C142797T"],"OPG164":["S7L"]},"labels":{"aa":"OPG164: S7L"}},"children":[{"name":"OP279036","node_attrs":{"div":559,"accession":"OP279036","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MpxV/human/CAN/UN-NML-4112/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-30"},"strain_display":{"value":"Canada/OP279036/2022-06-30"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP378695","node_attrs":{"div":559,"accession":"OP378695","author":{"author":"Gigante,C.M.,Hauser,J.R.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y.","value":"Gigante,C.M.,Hauser,J.R.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_USA_2022_DC0010"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP378695/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T4775-","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP920699","node_attrs":{"div":565,"accession":"OP920699","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00361/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-31"},"strain_display":{"value":"USA/OP920699/2022-10-31"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G105325A","C108658T","G111379A","C149889T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G165395A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G184244A"],"OPG124":["S215F"],"OPG130":["S175L"],"OPG190":["E92K"]},"labels":{"aa":"OPG124: S215F; OPG130: S175L; OPG190: E92K"}}},{"name":"OR264396","node_attrs":{"div":564,"accession":"OR264396","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"33_A"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-07"},"strain_display":{"value":"Australia/OR264396/2022-09-07"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["G14622A","A28529-","A28530-","T76084-","T76085-","G101241A","T133102-","C136244T","C156446T","G174708A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG025":["R216C"],"OPG044":["K147-"],"OPG153":["R475K"],"OPG204":["M59I"]},"labels":{"aa":"OPG025: R216C; OPG044: K147-; OPG153: R475K; OPG204: M59I"}}},{"name":"OR209323","node_attrs":{"div":560,"accession":"OR209323","author":{"author":"Li,C.M.","value":"Li,C.M."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_USA_2022_NC0003"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR209323/2022-12-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","G62268A","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","A196614-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OR759230","node_attrs":{"div":559,"accession":"OR759230","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"hMpxV/Canada/ON-PHOL146/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-01"},"strain_display":{"value":"Canada/OR759230/2022-07-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR759178","node_attrs":{"div":563,"accession":"OR759178","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"hMpxV/Canada/ON-PHOL090/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759178/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","G26352A","C30137T","C55072T","G130068A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"],"OPG042":["A249V"],"OPG047":["R353K"],"OPG073":["D24N"],"OPG151":["R382Q"]},"labels":{"aa":"OPG042: A249V; OPG047: R353K; OPG073: D24N; OPG151: R382Q"}}},{"name":"NODE_0000223","node_attrs":{"div":563,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C55036T","C96914T","G158254A","C170381T","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179176A","-179177T","-179178A","-179179T","-179180A"],"OPG073":["E36K"],"OPG117":["S289L"],"OPG198":["S115L"]},"labels":{"aa":"OPG073: E36K; OPG117: S289L; OPG198: S115L"}},"children":[{"name":"OQ918697","node_attrs":{"div":567,"accession":"OQ918697","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00486/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-18"},"strain_display":{"value":"USA/OQ918697/2023-02-18"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G73789A","C136435T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C166803T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","G178559A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG094":["G4R"],"OPG192":["P25S"]},"labels":{"aa":"OPG094: G4R; OPG192: P25S"}}},{"name":"OR464216","node_attrs":{"div":563,"accession":"OR464216","author":{"author":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y.","value":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_USA_2022_KS0007"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"USA/OR464216/2022-11-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T"]}}}]}]}]}]},{"name":"NODE_0000224","node_attrs":{"div":557,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G190660A"],"OPG016":["R84K"]},"labels":{"aa":"OPG016: R84K","clade":"B.1.3"}},"children":[{"name":"ON983168","node_attrs":{"div":557,"accession":"ON983168","author":{"author":"Chmel,M.,Pajer,P.,Nagy,A.,Zlamal,M.,Jirincova,H.,Dresler,J.,Bartos,O.","value":"Chmel,M.,Pajer,P.,Nagy,A.,Zlamal,M.,Jirincova,H.,Dresler,J.,Bartos,O."},"country":{"value":"Czech Republic"},"institution":{"value":"Military Heatlh Institute, Military Heatlh Institute in Prague"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPxV/Prague_001/2022/flye_medaka"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-04-28"},"strain_display":{"value":"Czech Republic/ON983168/2022-04-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T80849-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OP314959","node_attrs":{"div":558,"accession":"OP314959","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"country":{"value":"USA"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV22/human/USA-NE-111"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-03"},"strain_display":{"value":"USA/OP314959/2022-08-03"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C119884T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A","-196616A","-196617A"],"OPG137":["P95S"]},"labels":{"aa":"OPG137: P95S"}}},{"name":"OP536804","node_attrs":{"div":558,"accession":"OP536804","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"9000432"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536804/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","C6423A","C135775T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","T190787-","A196614-"]}}},{"name":"OR449633","node_attrs":{"div":557,"accession":"OR449633","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/ON/RKI919"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449633/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"NODE_0000225","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C39898T","C148933T","G171318A","C175241T"],"OPG057":["D100N"],"OPG174":["E155K"],"OPG199":["E111K"],"OPG204":["S237L"]},"labels":{"aa":"OPG057: D100N; OPG174: E155K; OPG199: E111K; OPG204: S237L"}},"children":[{"name":"OP205121","node_attrs":{"div":561,"accession":"OP205121","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_UK_2022_9000164"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-05"},"strain_display":{"value":"United Kingdom/OP205121/2022-07-05"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"OP415237","node_attrs":{"div":567,"accession":"OP415237","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPX_oJ2Z6R_9000271"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415237/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C5023T","C17196T","C80447T","C127215T","G150190A","C164347T","G192187A"],"OPG149":["S7L"],"OPG176":["D128N"],"OPG189":["R339C"]},"labels":{"aa":"OPG149: S7L; OPG176: D128N; OPG189: R339C"}}}]},{"name":"NODE_0000226","node_attrs":{"div":558,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C64426T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}},"children":[{"name":"OQ721953","node_attrs":{"div":565,"accession":"OQ721953","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"country":{"value":"Taiwan"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/human/Taiwan/110-525030/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-XX"},"strain_display":{"value":"Taiwan/OQ721953/2023-03-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C166940T","T177665A","A177666T","A177667T","G178104T","G178290T","T178629A","G196412A"],"OPG205":["N670K","N671F"]},"labels":{"aa":"OPG205: N670K, N671F"}}},{"name":"NODE_0000227","node_attrs":{"div":559,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G55133A"],"OPG074":["R665C"]},"labels":{"aa":"OPG074: R665C"}},"children":[{"name":"ON792320","node_attrs":{"div":560,"accession":"ON792320","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"country":{"value":"Switzerland"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba6449f/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-01"},"strain_display":{"value":"Switzerland/ON792320/2022-06-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G159376A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG185":["D154N"]},"labels":{"aa":"OPG185: D154N"}}},{"name":"ON782054","node_attrs":{"div":561,"accession":"ON782054","author":{"author":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"country":{"value":"Spain"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0001a/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-31"},"strain_display":{"value":"Spain/ON782054/2022-05-31"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G50337A","A122238T","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A169759G","A193392G","T193688C","T194099C","T194619C","T195948C","-196615A"],"OPG001_dup":["L105S"],"OPG002_dup":["F54S"],"OPG003_dup":["N264D"],"OPG069":["G118R"],"OPG143":["S360T"]},"labels":{"aa":"OPG001_dup: L105S; OPG002_dup: F54S; OPG003_dup: N264D; OPG069: G118R; OPG143: S360T"}}},{"name":"ON754987","node_attrs":{"div":560,"accession":"ON754987","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_SI2022_S1_VEROE6"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-23"},"strain_display":{"value":"Slovenia/ON754987/2022-05-23"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A33-","T157-","-607T","G167517A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG193":["E62K"]},"labels":{"aa":"OPG193: E62K"}}},{"name":"ON622722","node_attrs":{"div":560,"accession":"ON622722","country":{"value":"France"},"institution":{"value":"Virology, GENomique EPIdemiologique das maladies Infectieuses, France"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_FR_HCL0001_2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-22"},"strain_display":{"value":"France/ON622722/2022-05-22"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C109627A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG129":["A460S"]},"labels":{"aa":"OPG129: A460S"}}},{"name":"OP215273","node_attrs":{"div":561,"accession":"OP215273","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/RKI251"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP215273/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G5515A","T54004C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179259T","C191695T"]}}},{"name":"OP205133","node_attrs":{"div":560,"accession":"OP205133","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_UK_2022_9000188"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-29"},"strain_display":{"value":"United Kingdom/OP205133/2022-06-29"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","C142545T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG163":["S115F"]},"labels":{"aa":"OPG163: S115F"}}},{"name":"OP205067","node_attrs":{"div":559,"accession":"OP205067","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_UK_2022_9000061"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-27"},"strain_display":{"value":"United Kingdom/OP205067/2022-05-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OP523994","node_attrs":{"div":562,"accession":"OP523994","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/RKI392"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP523994/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G36659A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G174642A","C190444T"],"OPG016":["S12L"],"OPG055":["A142V"],"OPG204":["M37I"]},"labels":{"aa":"OPG016: S12L; OPG055: A142V; OPG204: M37I"}}},{"name":"OP605585","node_attrs":{"div":563,"accession":"OP605585","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"Slovenia-MPXV-44-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Slovenia/OP605585/2022-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","C8612T","G52232A","C56018T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G187156A"],"OPG071":["S736L"],"OPG074":["E370K"]},"labels":{"aa":"OPG071: S736L; OPG074: E370K"}}},{"name":"OP605552","node_attrs":{"div":559,"accession":"OP605552","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"Slovenia-MPXV-09-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Slovenia/OP605552/2022-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T38-","T157-","-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP605562","node_attrs":{"div":565,"accession":"OP605562","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"Slovenia-MPXV-20-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Slovenia/OP605562/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","A29748T","G72609A","G72610T","G72611T","T72614A","A72617C","A72977-","A72978-","T72979-","G72980-","A72981-"],"OPG047":["*483K"],"OPG092":["C111G","K112*","P113N","T114S"]},"labels":{"aa":"OPG047: *483K; OPG092: C111G, K112*, P113N, T114S"}}},{"name":"OP555633","node_attrs":{"div":560,"accession":"OP555633","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"Monkeypox/PT0562/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Portugal/OP555633/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168066T"],"OPG153":["D385-"],"OPG193":["Q245*"]},"labels":{"aa":"OPG153: D385-; OPG193: Q245*"}}},{"name":"OP555564","node_attrs":{"div":559,"accession":"OP555564","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"Monkeypox/PT0488/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-11"},"strain_display":{"value":"Portugal/OP555564/2022-08-11"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP879736","node_attrs":{"div":559,"accession":"OP879736","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"country":{"value":"USA"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"NJ-MPXV-017-rep2"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-29"},"strain_display":{"value":"USA/OP879736/2022-06-29"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ274889","node_attrs":{"div":559,"accession":"OQ274889","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/ON/RKI670"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ274889/2022-05-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OR035715","node_attrs":{"div":559,"accession":"OR035715","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/UZ_REGA_109"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035715/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"]}}},{"name":"OR035686","node_attrs":{"div":560,"accession":"OR035686","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/UZ_REGA_80"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-09"},"strain_display":{"value":"Belgium/OR035686/2022-08-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C22950T","T133101-","T133102-","C133161T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ773470","node_attrs":{"div":559,"accession":"OQ773470","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/ON/RKI851"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773470/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-"]}}},{"name":"OR264391","node_attrs":{"div":559,"accession":"OR264391","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"2_A"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-08-10"},"strain_display":{"value":"Australia/OR264391/2022-08-10"},"clade_membership":{"value":"IIb"},"region":{"value":"Oceania"}},"branch_attrs":{"mutations":{"nuc":["T80846-","T80847-","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OR134560","node_attrs":{"div":570,"accession":"OR134560","author":{"author":"Miller,H.,Bajwa,M.","value":"Miller,H.,Bajwa,M."},"country":{"value":"USA"},"institution":{"value":"Delaware Public Health Lab, Sequencing/Bioinformatics"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"B1221136"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-13"},"strain_display":{"value":"USA/OR134560/2023-03-13"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C19558T","G32277A","C35688T","G39140A","G55059A","G75512A","C110402T","C121161T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C170673T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179542T","C189174T"],"OPG034":["E150K"],"OPG049":["S292L"],"OPG073":["S28L"],"OPG095":["R237K"],"OPG139":["A70T"]},"labels":{"aa":"OPG034: E150K; OPG049: S292L; OPG073: S28L; OPG095: R237K; OPG139: A70T"}}},{"name":"OX248696","node_attrs":{"div":561,"accession":"OX248696","country":{"value":"Slovakia"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"RNA"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-04"},"strain_display":{"value":"Slovakia/OX248696/2022-07-04"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","G37250A","C138080T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG155":["E138K"]},"labels":{"aa":"OPG155: E138K"}}},{"name":"ON782021","node_attrs":{"div":559,"accession":"ON782021","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O."},"country":{"value":"Finland"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPX-37/Finland/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-24"},"strain_display":{"value":"Finland/ON782021/2022-05-24"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ557947","node_attrs":{"div":559,"accession":"OQ557947","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_USA_2022_NY0008"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OQ557947/2022-07-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A"]}}},{"name":"NODE_0000228","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A140126-","C140127-","T168120C","-179234A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-"],"OPG159":["N120-"],"OPG193":["F263L"]},"labels":{"aa":"OPG159: N120-; OPG193: F263L"}},"children":[{"name":"OP144214","node_attrs":{"div":561,"accession":"OP144214","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P."},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/ITM_pt_25/Belgium/16-Jun-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-06-16"},"strain_display":{"value":"Belgium/OP144214/2022-06-16"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C133161T","C157632T"]}}},{"name":"ON950045","node_attrs":{"div":560,"accession":"ON950045","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,Van den Bossche,D.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Van Esbroeck,M.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,Van den Bossche,D.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Van Esbroeck,M."},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/ITM_pt_31/Belgium/27-May-2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-05-27"},"strain_display":{"value":"Belgium/ON950045/2022-05-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T133102-","A140104-","A140105-","T140106-","A140107-","A140108-","C140109-","A140110-","A140111-","T140112-","T140113-","A140114-","T140115-","A140116-","A140117-","C140118-","A140119-","A140120-","T140121-","T140122-","A140123-","T140124-","A140125-","A140128-","A140129-","T140130-","T140131-","A140132-","T140133-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","A140143-","A140144-","T140145-","T140146-","G140147-","T140148-","T140149-","A140150-","T140151-","A140152-","A140153-","T140154-","A140155-","A140156-","T140157-","T140158-","A140159-","T140160-","A140161-","A140162-","T140163-","T140164-","G140165-","T140166-","T140167-","T179267-","-196615A"],"OPG159":["N113-","N114-","N115-","Y116-","N117-","N118-","Y119-","N121-","Y122-","N123-","N124-","Y125-","N126-","C127-","Y128-","N129-","N130-","Y131-","N132-","C133-","Y134-"]},"labels":{"aa":"OPG159: N113-, N114-, N115-, Y116-, N117-, N118-, Y119-, N121-, Y122-, N123-, N124-, Y125-, N126-, C127-, Y128-, N129-, N130-, Y131-, N132-, C133-, Y134-"}}}]},{"name":"NODE_0000230","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C133161T","C157632T"]}},"children":[{"name":"OP555472","node_attrs":{"div":561,"accession":"OP555472","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"Monkeypox/PT0376/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-07"},"strain_display":{"value":"Portugal/OP555472/2022-07-07"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159243A"]}}},{"name":"OR086974","node_attrs":{"div":561,"accession":"OR086974","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/UZ_REGA_165/Belgium/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR086974/2022-07-27"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["G41336A","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000231","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G152776A"],"OPG180":["D29N"]},"labels":{"aa":"OPG180: D29N"}},"children":[{"name":"OQ451903","node_attrs":{"div":571,"accession":"OQ451903","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2023/RKI718"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-XX"},"strain_display":{"value":"Germany/OQ451903/2023-01-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-607T","C15969T","C17998T","G40610A","C43803T","C63879T","G70190A","G118289A","C147011T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C159532T","G161629A","C189427T"],"OPG005":["P77S"],"OPG027":["E137K"],"OPG031":["M277I"],"OPG064":["G699E"],"OPG083":["D280N"],"OPG089":["E109K"],"OPG185":["P206S"],"OPG188":["E12K"]},"labels":{"aa":"OPG005: P77S; OPG027: E137K; OPG031: M277I; OPG064: G699E; OPG083: D280N; OPG089: E109K; OPG185: P206S; OPG188: E12K"}}},{"name":"OQ581854","node_attrs":{"div":562,"accession":"OQ581854","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"country":{"value":"Taiwan"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/human/Taiwan/109-005210/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-XX"},"strain_display":{"value":"Taiwan/OQ581854/2023-02-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["T64426C","G158406A","A192404-","G192405-","T192406-","A192411-"]}}}]},{"name":"NODE_0000232","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G85581A"],"OPG107":["V24I"]},"labels":{"aa":"OPG107: V24I"}},"children":[{"name":"OQ320451","node_attrs":{"div":561,"accession":"OQ320451","author":{"author":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y.","value":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y."},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_USA_2022_DC0022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ320451/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C112740T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A"]}}},{"name":"OR759179","node_attrs":{"div":561,"accession":"OR759179","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"B.1.3"},"strain":{"value":"hMpxV/Canada/ON-PHOL091/2022"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759179/2022-09-01"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["C122502T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG143":["D272N"]},"labels":{"aa":"OPG143: D272N"}}}]},{"name":"NODE_0000233","node_attrs":{"div":560,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G105923A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG124":["L16F"]},"labels":{"aa":"OPG124: L16F","clade":"C.1"}},"children":[{"name":"LC753968","node_attrs":{"div":560,"accession":"LC753968","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"country":{"value":"Japan"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220165"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Japan/LC753968/2022-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{}}},{"name":"LC753969","node_attrs":{"div":560,"accession":"LC753969","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"country":{"value":"Japan"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220176"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"Japan/LC753969/2022-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{}}},{"name":"OR035728","node_attrs":{"div":561,"accession":"OR035728","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/UZ_REGA_122"},"host":{"value":"Homo sapiens"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035728/2022-10-28"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G149818A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG176":["D4N"]},"labels":{"aa":"OPG176: D4N"}}},{"name":"OQ581853","node_attrs":{"div":562,"accession":"OQ581853","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"country":{"value":"Taiwan"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Taiwan/110-093831/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-XX"},"strain_display":{"value":"Taiwan/OQ581853/2023-02-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["T132513C","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C185069T"]}}},{"name":"NODE_0000234","node_attrs":{"div":561,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C166940T","G193223A"]}},"children":[{"name":"OQ721952","node_attrs":{"div":568,"accession":"OQ721952","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"country":{"value":"Taiwan"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Taiwan/240031000030/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-XX"},"strain_display":{"value":"Taiwan/OQ721952/2023-03-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["C798T","C13503T","G33539A","G34948A","G40174A","G156025A","A183935G","A184219G"],"OPG025":["A589T"],"OPG054":["A350V"],"OPG057":["P8S"],"OPG210":["I860M","Y955C"]},"labels":{"aa":"OPG025: A589T; OPG054: A350V; OPG057: P8S; OPG210: I860M, Y955C"}}},{"name":"NODE_0000235","node_attrs":{"div":562,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C3987T"]}},"children":[{"name":"LC756925","node_attrs":{"div":563,"accession":"LC756925","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"country":{"value":"Japan"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220342"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-02-09"},"strain_display":{"value":"Japan/LC756925/2023-02-09"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["C84734T"]}}},{"name":"LC756923","node_attrs":{"div":562,"accession":"LC756923","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"country":{"value":"Japan"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220318"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-01-25"},"strain_display":{"value":"Japan/LC756923/2023-01-25"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{}}},{"name":"OR427348","node_attrs":{"div":565,"accession":"OR427348","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MpxV/human/USA/WA-UW-066957/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-06-XX"},"strain_display":{"value":"USA/OR427348/2023-06-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G26855A","C30191T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C155490T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG047":["R335H"]},"labels":{"aa":"OPG047: R335H"}}},{"name":"OR665166","node_attrs":{"div":567,"accession":"OR665166","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MpxV/human/USA/WA-UW-092809/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-09-XX"},"strain_display":{"value":"USA/OR665166/2023-09-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["T606-","G13434A","G29650A","C33332T","G37974A","C74691T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG025":["R612C"],"OPG046":["T27I"],"OPG050":["R26Q"],"OPG056":["S354L"]},"labels":{"aa":"OPG025: R612C; OPG046: T27I; OPG050: R26Q; OPG056: S354L"}}},{"name":"OR499979","node_attrs":{"div":565,"accession":"OR499979","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00522/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-05-08"},"strain_display":{"value":"USA/OR499979/2023-05-08"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G11924A","C134237T","G178951A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG023":["S326L"]},"labels":{"aa":"OPG023: S326L"}}},{"name":"OR459802","node_attrs":{"div":563,"accession":"OR459802","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"country":{"value":"South Korea"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV-ROK-P032-2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-04-25"},"strain_display":{"value":"South Korea/OR459802/2023-04-25"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["C52108T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000236","node_attrs":{"div":564,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C149963T","G184562A"],"OPG176":["S52L"]},"labels":{"aa":"OPG176: S52L"}},"children":[{"name":"OR459778","node_attrs":{"div":565,"accession":"OR459778","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"country":{"value":"South Korea"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV-ROK-P005-2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-03-13"},"strain_display":{"value":"South Korea/OR459778/2023-03-13"},"clade_membership":{"value":"IIb"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["G85691A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000237","node_attrs":{"div":567,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C21062T","G188348A","C188946T"],"OPG036":["M1I"]},"labels":{"aa":"OPG036: M1I"}},"children":[{"name":"OR643705","node_attrs":{"div":573,"accession":"OR643705","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00563/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-08-16"},"strain_display":{"value":"USA/OR643705/2023-08-16"},"clade_membership":{"value":"IIb"},"region":{"value":"North America"}},"branch_attrs":{"mutations":{"nuc":["G21880A","G47532A","C125074T","G133704A","G133838A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T180483A"],"OPG037":["S185F"]},"labels":{"aa":"OPG037: S185F"}}},{"name":"NODE_0000238","node_attrs":{"div":569,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G101241A","G152866A"],"OPG180":["D59N"]},"labels":{"aa":"OPG180: D59N"}},"children":[{"name":"OR743500","node_attrs":{"div":572,"accession":"OR743500","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1031"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-10-XX"},"strain_display":{"value":"Germany/OR743500/2023-10-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T57476C","C142797T","G173397A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-"],"OPG075":["Q8R"],"OPG164":["S7L"]},"labels":{"aa":"OPG075: Q8R; OPG164: S7L"}}},{"name":"NODE_0000239","node_attrs":{"div":570,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G13563A"],"OPG025":["P569S"]},"labels":{"aa":"OPG025: P569S"}},"children":[{"name":"OR381843","node_attrs":{"div":570,"accession":"OR381843","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"Monkeypox/PT0649/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-07-10"},"strain_display":{"value":"Portugal/OR381843/2023-07-10"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000240","node_attrs":{"div":572,"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T611-","C37738T","G151847A","C191053-","A191054-","T191055-","G191056-","G191057-","A191058-","G191059-","T191060-","C191061-","G191062-","G191063-","T191064-","A191065-","G191066-","A191067-","T191068-","T191069-","T191070-","C191071-","A191072-","T191073-","G191074-","G191075-","C191076-","T191077-","G191078-","T191079-","C191080-","G191081-","A191082-","T191083-","G191084-","A191085-","G191086-","C191087-","A191088-","G191089-","T191090-","T191091-","T191092-","C191093-","A191094-","C191095-","G191096-","A191097-","C191098-","G191099-","A191100-","C191101-","C191102-","T191103-","C191104-","G191105-","A191106-","T191107-","C191108-","T191109-","T191110-","T191111-","G191112-","G191113-","T191114-","C191115-","A191116-","T191117-","T191118-","A191119-","T191120-","C191121-","T191122-","T191123-","T191124-","G191125-","G191126-","T191127-","A191128-","G191129-"],"OPG056":["E433K"]},"labels":{"aa":"OPG056: E433K"}},"children":[{"name":"OR326997","node_attrs":{"div":572,"accession":"OR326997","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/PT0633/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-06-25"},"strain_display":{"value":"Portugal/OR326997/2023-06-25"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-608T","G610-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-"]}}},{"name":"OR519723","node_attrs":{"div":576,"accession":"OR519723","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-08-XX"},"strain_display":{"value":"Germany/OR519723/2023-08-XX"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["-611T","C56879T","C57492T","G121291A","G172945A"],"OPG074":["E83K"],"OPG075":["E3K"]},"labels":{"aa":"OPG074: E83K; OPG075: E3K"}}},{"name":"OR487988","node_attrs":{"div":572,"accession":"OR487988","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"outbreak":{"value":"hMPXV-1"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/PT0667/2023"},"host":{"value":"Homo sapiens"},"date":{"value":"2023-08-01"},"strain_display":{"value":"Portugal/OR487988/2023-08-01"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["A784-","T785-","T196689-","C196690-"]}}}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}} \ No newline at end of file diff --git a/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/CHANGELOG.md b/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/CHANGELOG.md new file mode 100644 index 00000000..8be55b7b --- /dev/null +++ b/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/CHANGELOG.md @@ -0,0 +1,14 @@ +## Unreleased + +Initial release of this dataset. This dataset is similar to the v2 dataset [`hMPXV/NC_063383.1`](https://github.com/nextstrain/nextclade_data/tree/2023-08-17--15-51-24--UTC/data/datasets/hMPXV/references/NC_063383.1/versions/2023-08-01T12%3A00%3A00Z/files) with some differences. + +Read more about Nextclade datasets in the documentation: https://docs.nextstrain.org/projects/nextclade/en/stable/user/datasets.html + +### Important changes compared to v2 dataset + +- Some genes have been renamed and one has been added. The new annotation is based on NCBI refseq annotations that were released in November 2022. The v2 dataset predates this refseq. + - The 4 genes in the inverted terminal repeat segment (ITR) on both ends of the genome (OPG001, OPG002, OPG003,OPG015) are now all included. The genes on the 3' end (~positions 190000-197000) now have an `_dup` appended to distinguish them. + - The gene previously named `NBT03_gp052` is now called `OPG073` + - The gene previously named `NBT03_gp174` is now called `OPG016` + - The gene previously named `NBT03_gp175` is now called `OPG015_dup` + - Gene `OPG166` has been added diff --git a/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/README.md b/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/README.md new file mode 100644 index 00000000..f346b92b --- /dev/null +++ b/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/README.md @@ -0,0 +1,27 @@ +# Nextclade dataset for "Mpox virus (Clade IIb)" + +| property | value | +| ------------------- | ------------------------------------------------------------------------------------------------------------------------------------------------------- | +| authors | [Cornelius Roemer](https://neherlab.org), [Richard Neher](https://neherlab.org), [Nextstrain](https://nextstrain.org) | +| data source | Genbank | +| workflow | [github.com/nextstrain/mpox/nextclade](https://github.com/nextstrain/mpox/nextclade) | +| issue tracker | github.com/nextstrain/mpox/issues | +| nextclade data path | nextstrain/mpox/lineage-iib/rivers +| title | Mpox virus (Clade IIb) | +| taxon | [NCBI:txid10244](https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=10244) | +| annotation | [NC_063383.1](https://www.ncbi.nlm.nih.gov/nuccore/NC_063383) | +| clade definitions | github.com/mpxv-lineages/lineage-designation | +| references | [Urgent need for a non-discriminatory and non-stigmatizing nomenclature for monkeypox virus](https://doi.org/10.1371/journal.pbio.3001769) | +| related datasets | Mpox virus (All clades): `nextstrain/mpox/all-clades/rivers-with-ancestral-snps`
Mpox virus (Lineage B.1) `nextstrain/mpox/lineage-iib/rivers-with-usa-2022-ma001-snps` | + +This Nextclade dataset is intended for use with Mpox viruses that fall within clade IIb. If your sequences are all or mostly descended from the 2022 outbreak lineage B.1 you may want to use the even more specific dataset for that lineage instead: `nextstrain/mpox/lineage-iib/rivers-with-usa-2022-ma001-snps`. If you want to analyze broader Mpox diversity, i.e. also clade I or clade II, use the more general dataset `nextstrain/mpox/all-clades/rivers-with-ancestral-snps`. The more specific a dataset, the faster it will run and the less overwhelming the results will be (fewer SNPs), more relevant reference sequences will be included for tree placement. Sequences that are beyond the scope of a dataset will still be included in the results but will get assigned to the fallback clade `outgroup`. + +This dataset supports calling all designated lineages within the clade IIb (A, A.1, A.2, A.3, A.1.1, B.1, etc.). The clade and lineage nomenclature used is outlined in [Urgent need for a non-discriminatory and non-stigmatizing nomenclature for monkeypox virus](https://doi.org/10.1371/journal.pbio.3001769). The ground truth for lineage definitions is available at [github.com/mpxv-lineages/lineage-designation](https://github.com/nextstrain/mpox/nextclade). This dataset will be updated as new lineages are designated. + +The reference used in this dataset is based on mpox virus NCBI refseq NC_063383.1 (`MPXV-M5312_HM12_Rivers`). + +The sequences used for construction of the reference tree are obtained from the `/ingest` workflow of the `nextstrain/monkeypox` repo. This workflow downloads and processes sequences from NCBI/Genbank. Sequences are sampled from all clades and all lineages over time and countries for a representative sample of the diversity of Mpox virus. The sequences are then aligned with Nextclade and a maximum likelihood tree is inferred with IQ-TREE. The tree is then rooted with the reconstructed ancestral sequence and ancestral states are inferred with TreeTime. + +## Further reading + +Read more about Nextclade datasets in Nextclade documentation: https://docs.nextstrain.org/projects/nextclade/en/stable/user/datasets.html diff --git a/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/genome_annotation.gff3 b/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/genome_annotation.gff3 new file mode 100644 index 00000000..432d5465 --- /dev/null +++ b/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/genome_annotation.gff3 @@ -0,0 +1,391 @@ +##gff-version 3 +#!gff-spec-version 1.21 +#!processor NCBI annotwriter +##sequence-region NC_063383.1 1 197209 +##species https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10244 +NC_063383.1 RefSeq region 1 197209 . + . ID=NC_063383.1:1..197209;Dbxref=taxon:10244;collection-date=2018-08;country=Nigeria: Rivers State;gbkey=Src;genome=genomic;genotype=MPXV clade 2;isolate=MPXV-M5312_HM12_Rivers;mol_type=genomic DNA;nat-host=Homo sapiens +NC_063383.1 RefSeq long_terminal_repeat 1 6422 . - . ID=id-NC_063383.1:1..6422;gbkey=repeat_region;rpt_type=long_terminal_repeat +NC_063383.1 RefSeq gene 835 1575 . - . ID=gene-NBT03_gp001;Dbxref=GeneID:72551607;Name=OPG001;gbkey=Gene;gene=OPG001;gene_biotype=protein_coding;locus_tag=NBT03_gp001;old_locus_tag=MPXV-M5312_HM12_Rivers-001 +NC_063383.1 RefSeq CDS 835 1575 . - 0 ID=cds-YP_010377002.1;Parent=gene-NBT03_gp001;Dbxref=GenBank:YP_010377002.1,GeneID:72551607;Name=OPG001;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp001%3B Chemokine binding protein (Cop-C23L)%3B most abundant secreted protein%3B CC-chemokine binding%3B similar to VACV-WR J1L and VACV-Cop C23L;gbkey=CDS;gene=OPG001;locus_tag=NBT03_gp001;product=Chemokine binding protein;protein_id=YP_010377002.1 +NC_063383.1 RefSeq gene 1702 2751 . - . ID=gene-NBT03_gp002;Dbxref=GeneID:72551418;Name=OPG002;gbkey=Gene;gene=OPG002;gene_biotype=protein_coding;locus_tag=NBT03_gp002;old_locus_tag=MPXV-M5312_HM12_Rivers-002 +NC_063383.1 RefSeq CDS 1702 2751 . - 0 ID=cds-YP_010377003.1;Parent=gene-NBT03_gp002;Dbxref=GenBank:YP_010377003.1,GeneID:72551418;Name=OPG002;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: NBT03_gp002%3B TNF receptor (CrmB)%3B similar to VACV-WR J2L and VACV-Cop C22L;gbkey=CDS;gene=OPG002;locus_tag=NBT03_gp002;product=Crm-B secreted TNF-alpha-receptor-like protein;protein_id=YP_010377003.1 +NC_063383.1 RefSeq gene 2841 4607 . - . ID=gene-NBT03_gp003;Dbxref=GeneID:72551419;Name=OPG003;gbkey=Gene;gene=OPG003;gene_biotype=protein_coding;locus_tag=NBT03_gp003;old_locus_tag=MPXV-M5312_HM12_Rivers-003 +NC_063383.1 RefSeq CDS 2841 4607 . - 0 ID=cds-YP_010377004.1;Parent=gene-NBT03_gp003;Dbxref=GenBank:YP_010377004.1,GeneID:72551419;Name=OPG003;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp003%3B Ankyrin%3B similar to VACV-WR J3L and VACV-Cop C19L;gbkey=CDS;gene=OPG003;locus_tag=NBT03_gp003;product=Ankyrin repeat protein (25);protein_id=YP_010377004.1 +NC_063383.1 RefSeq gene 4843 6156 . - . ID=gene-NBT03_gp004;Dbxref=GeneID:72551420;Name=OPG015;gbkey=Gene;gene=OPG015;gene_biotype=protein_coding;locus_tag=NBT03_gp004;old_locus_tag=MPXV-M5312_HM12_Rivers-004 +NC_063383.1 RefSeq CDS 4843 6156 . - 0 ID=cds-YP_010377005.1;Parent=gene-NBT03_gp004;Dbxref=GenBank:YP_010377005.1,GeneID:72551420;Name=OPG015;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp004%3B Ankyrin%3B similar to VACV-WR D1L and CPXV-017;gbkey=CDS;gene=OPG015;locus_tag=NBT03_gp004;product=Ankyrin repeat protein (39);protein_id=YP_010377005.1 +NC_063383.1 RefSeq sequence_feature 6270 6419 . - . ID=id-NC_063383.1:6270..6419;exon_number=OPG016;gbkey=misc_feature;number=OPG016 +NC_063383.1 RefSeq sequence_feature 6444 6885 . - . ID=id-NC_063383.1:6444..6885;exon_number=OPG017;gbkey=misc_feature;number=OPG017 +NC_063383.1 RefSeq sequence_feature 6966 7463 . - . ID=id-NC_063383.1:6966..7463;exon_number=OPG018;gbkey=misc_feature;number=OPG018 +NC_063383.1 RefSeq gene 7580 8008 . + . ID=gene-NBT03_gp005;Dbxref=GeneID:72551421;Name=OPG019;gbkey=Gene;gene=OPG019;gene_biotype=protein_coding;locus_tag=NBT03_gp005;old_locus_tag=MPXV-M5312_HM12_Rivers-006 +NC_063383.1 RefSeq CDS 7580 8008 . + 0 ID=cds-YP_010377006.1;Parent=gene-NBT03_gp005;Dbxref=GenBank:YP_010377006.1,GeneID:72551421;Name=OPG019;Note=Taxonomic breadth: chordopoxvirinae%3B secreted growth factor Secreted EGF-like protein%3B similar to VACV-WR D3R and VACV-Cop C11R;gbkey=CDS;gene=OPG019;locus_tag=NBT03_gp005;product=EGF-like domain protein;protein_id=YP_010377006.1 +NC_063383.1 RefSeq sequence_feature 8136 9102 . - . ID=id-NC_063383.1:8136..9102;exon_number=OPG020;gbkey=misc_feature;number=OPG020 +NC_063383.1 RefSeq gene 9587 10315 . + . ID=gene-NBT03_gp006;Dbxref=GeneID:72551422;Name=OPG021;gbkey=Gene;gene=OPG021;gene_biotype=protein_coding;locus_tag=NBT03_gp006;old_locus_tag=MPXV-M5312_HM12_Rivers-008 +NC_063383.1 RefSeq CDS 9587 10315 . + 0 ID=cds-YP_010377007.1;Parent=gene-NBT03_gp006;Dbxref=GenBank:YP_010377007.1,GeneID:72551422;Name=OPG021;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp008%3B Zinc finger-like protein%3B zinc binding%3B virosome localization%3B virulence factor%3B inhibition of apoptosis induced by UV irradiation%3B similar to VACV-WR D5R;gbkey=CDS;gene=OPG021;locus_tag=NBT03_gp006;product=Zinc finger-like protein (2);protein_id=YP_010377007.1 +NC_063383.1 RefSeq gene 10478 10858 . - . ID=gene-NBT03_gp007;Dbxref=GeneID:72551423;Name=OPG022;gbkey=Gene;gene=OPG022;gene_biotype=protein_coding;locus_tag=NBT03_gp007;old_locus_tag=MPXV-M5312_HM12_Rivers-009 +NC_063383.1 RefSeq CDS 10478 10858 . - 0 ID=cds-YP_010377008.1;Parent=gene-NBT03_gp007;Dbxref=GenBank:YP_010377008.1,GeneID:72551423;Name=OPG022;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp009%3B secreted IL-18 binding protein%3B Soluble IL-18 binding protein (Bsh-D7L)%3B similar to VACV-WR D6L;gbkey=CDS;gene=OPG022;locus_tag=NBT03_gp007;product=Interleukin-18-binding protein;protein_id=YP_010377008.1 +NC_063383.1 RefSeq gene 10918 12900 . - . ID=gene-NBT03_gp008;Dbxref=GeneID:72551424;Name=OPG023;gbkey=Gene;gene=OPG023;gene_biotype=protein_coding;locus_tag=NBT03_gp008;old_locus_tag=MPXV-M5312_HM12_Rivers-010 +NC_063383.1 RefSeq CDS 10918 12900 . - 0 ID=cds-YP_010377009.1;Parent=gene-NBT03_gp008;Dbxref=GenBank:YP_010377009.1,GeneID:72551424;Name=OPG023;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp010%3B host range%3B ankyrin-like%3B Ankyrin/Host Range (Bang-D8L)%3B similar to VACV-WR D7L;gbkey=CDS;gene=OPG023;locus_tag=NBT03_gp008;product=Ankyrin repeat protein (2);protein_id=YP_010377009.1 +NC_063383.1 RefSeq gene 13034 13228 . - . ID=gene-NBT03_gp009;Dbxref=GeneID:72551425;Name=OPG024;gbkey=Gene;gene=OPG024;gene_biotype=protein_coding;locus_tag=NBT03_gp009;old_locus_tag=MPXV-M5312_HM12_Rivers-011 +NC_063383.1 RefSeq CDS 13034 13228 . - 0 ID=cds-YP_010377010.1;Parent=gene-NBT03_gp009;Dbxref=GenBank:YP_010377010.1,GeneID:72551425;Name=OPG024;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp011%3B ANK-containing protein%3B similar to VACV-WR D8L;gbkey=CDS;gene=OPG024;locus_tag=NBT03_gp009;product=retroviral pseudoprotease-like protein;protein_id=YP_010377010.1 +NC_063383.1 RefSeq gene 13375 15267 . - . ID=gene-NBT03_gp010;Dbxref=GeneID:72551426;Name=OPG025;gbkey=Gene;gene=OPG025;gene_biotype=protein_coding;locus_tag=NBT03_gp010;old_locus_tag=MPXV-M5312_HM12_Rivers-012 +NC_063383.1 RefSeq CDS 13375 15267 . - 0 ID=cds-YP_010377011.1;Parent=gene-NBT03_gp010;Dbxref=GenBank:YP_010377011.1,GeneID:72551426;Name=OPG025;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp012%3B ankyrin-like%3B Type I IFN resistance%3B similar to VACV-WR D9L and VACV-Cop C9L;gbkey=CDS;gene=OPG025;locus_tag=NBT03_gp010;product=Ankyrin repeat protein (14);protein_id=YP_010377011.1 +NC_063383.1 RefSeq sequence_feature 15310 15854 . - . ID=id-NC_063383.1:15310..15854;exon_number=OPG026;gbkey=misc_feature;number=OPG026 +NC_063383.1 RefSeq gene 15925 16377 . - . ID=gene-NBT03_gp011;Dbxref=GeneID:72551427;Name=OPG027;gbkey=Gene;gene=OPG027;gene_biotype=protein_coding;locus_tag=NBT03_gp011;old_locus_tag=MPXV-M5312_HM12_Rivers-013 +NC_063383.1 RefSeq CDS 15925 16377 . - 0 ID=cds-YP_010377012.1;Parent=gene-NBT03_gp011;Dbxref=GenBank:YP_010377012.1,GeneID:72551427;Name=OPG027;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp013%3B host range%3B Type 1 IFN inhibitor%3B similar to VACV-WR D10L and VACV-Cop C7L;gbkey=CDS;gene=OPG027;locus_tag=NBT03_gp011;product=Host range protein;protein_id=YP_010377012.1 +NC_063383.1 RefSeq gene 16602 17069 . - . ID=gene-NBT03_gp012;Dbxref=GeneID:72551428;Name=OPG029;gbkey=Gene;gene=OPG029;gene_biotype=protein_coding;locus_tag=NBT03_gp012;old_locus_tag=MPXV-M5312_HM12_Rivers-014 +NC_063383.1 RefSeq CDS 16602 17069 . - 0 ID=cds-YP_010377013.1;Parent=gene-NBT03_gp012;Dbxref=GenBank:YP_010377013.1,GeneID:72551428;Name=OPG029;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp014%3B Putative tlr signaling inhibitor%2C IFN-beta inhibitor%3B similar to VACV-WR D11L and VACV-Cop C6L;gbkey=CDS;gene=OPG029;locus_tag=NBT03_gp012;product=Bcl-2-like protein;protein_id=YP_010377013.1 +NC_063383.1 RefSeq gene 17213 17833 . - . ID=gene-NBT03_gp013;Dbxref=GeneID:72551429;Name=OPG030;gbkey=Gene;gene=OPG030;gene_biotype=protein_coding;locus_tag=NBT03_gp013;old_locus_tag=MPXV-M5312_HM12_Rivers-015 +NC_063383.1 RefSeq CDS 17213 17833 . - 0 ID=cds-YP_010377014.1;Parent=gene-NBT03_gp013;Dbxref=GenBank:YP_010377014.1,GeneID:72551429;Name=OPG030;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp015%3B BTB domain of kelch-like protein%3B Kelch-like protein%3B similar to VACV-WR D12L and VACV-Cop C5L;gbkey=CDS;gene=OPG030;locus_tag=NBT03_gp013;product=Kelch-like protein (1);protein_id=YP_010377014.1 +NC_063383.1 RefSeq gene 17878 18828 . - . ID=gene-NBT03_gp014;Dbxref=GeneID:72551430;Name=OPG031;gbkey=Gene;gene=OPG031;gene_biotype=protein_coding;locus_tag=NBT03_gp014;old_locus_tag=MPXV-M5312_HM12_Rivers-016 +NC_063383.1 RefSeq CDS 17878 18828 . - 0 ID=cds-YP_010377015.1;Parent=gene-NBT03_gp014;Dbxref=GenBank:YP_010377015.1,GeneID:72551430;Name=OPG031;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp016%3B IL-1 receptor antagonist%3B similar to VACV-WR D13L and VACV-Cop C10L;gbkey=CDS;gene=OPG031;locus_tag=NBT03_gp014;product=C4L/C10L-like family protein;protein_id=YP_010377015.1 +NC_063383.1 RefSeq sequence_feature 18902 19288 . - . ID=id-NC_063383.1:18902..19288;exon_number=OPG033;gbkey=misc_feature;number=OPG033 +NC_063383.1 RefSeq gene 19361 20005 . - . ID=gene-NBT03_gp015;Dbxref=GeneID:72551431;Name=OPG034;gbkey=Gene;gene=OPG034;gene_biotype=protein_coding;locus_tag=NBT03_gp015;old_locus_tag=MPXV-M5312_HM12_Rivers-018 +NC_063383.1 RefSeq CDS 19361 20005 . - 0 ID=cds-YP_010377017.1;Parent=gene-NBT03_gp015;Dbxref=GenBank:YP_010377017.1,GeneID:72551431;Name=OPG034;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp022%3B Putative TLR signalling inhibitor%3B start of ORF is missing approx. 18 AA compared to CPXVs%3B similar to VACV-WR D19L and VACV-Cop C1L;gbkey=CDS;gene=OPG034;locus_tag=NBT03_gp015;product=Bcl-2-like protein;protein_id=YP_010377017.1 +NC_063383.1 RefSeq gene 20051 20404 . - . ID=gene-NBT03_gp016;Dbxref=GeneID:72551432;Name=OPG035;gbkey=Gene;gene=OPG035;gene_biotype=protein_coding;locus_tag=NBT03_gp016;old_locus_tag=MPXV-M5312_HM12_Rivers-019 +NC_063383.1 RefSeq CDS 20051 20404 . - 0 ID=cds-YP_010377018.1;Parent=gene-NBT03_gp016;Dbxref=GenBank:YP_010377018.1,GeneID:72551432;Name=OPG035;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp023%3B secreted virulence factor%3B Putative tlr signaling inhibitor%3B Anti-apoptotic Bcl-2-like protein%3B similar to VACV-WR P1L and VACV-Cop N1L;gbkey=CDS;gene=OPG035;locus_tag=NBT03_gp016;product=Bcl-2-like protein;protein_id=YP_010377018.1 +NC_063383.1 RefSeq gene 20531 21064 . - . ID=gene-NBT03_gp017;Dbxref=GeneID:72551433;Name=OPG036;gbkey=Gene;gene=OPG036;gene_biotype=protein_coding;locus_tag=NBT03_gp017;old_locus_tag=MPXV-M5312_HM12_Rivers-020 +NC_063383.1 RefSeq CDS 20531 21064 . - 0 ID=cds-YP_010377019.1;Parent=gene-NBT03_gp017;Dbxref=GenBank:YP_010377019.1,GeneID:72551433;Name=OPG036;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp024%3B Alpha amanatin target protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR P2L and VACV-Cop #N2L;gbkey=CDS;gene=OPG036;locus_tag=NBT03_gp017;product=Bcl-2-like protein;protein_id=YP_010377019.1 +NC_063383.1 RefSeq gene 21105 22433 . - . ID=gene-NBT03_gp018;Dbxref=GeneID:72551434;Name=OPG037;gbkey=Gene;gene=OPG037;gene_biotype=protein_coding;locus_tag=NBT03_gp018;old_locus_tag=MPXV-M5312_HM12_Rivers-021 +NC_063383.1 RefSeq CDS 21105 22433 . - 0 ID=cds-YP_010377020.1;Parent=gene-NBT03_gp018;Dbxref=GenBank:YP_010377020.1,GeneID:72551434;Name=OPG037;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp025%3B ankyrin-like%3B ANK-containing protein%3B apoptosis inhibitor%3B start of ORF is missing approx. 31 AA compared to CPXVs%3B similar to VACV-WR O1L and VACV-Cop M1L;gbkey=CDS;gene=OPG037;locus_tag=NBT03_gp018;product=Ankyrin-like protein (1);protein_id=YP_010377020.1 +NC_063383.1 RefSeq gene 22497 23159 . - . ID=gene-NBT03_gp019;Dbxref=GeneID:72551435;Name=OPG038;gbkey=Gene;gene=OPG038;gene_biotype=protein_coding;locus_tag=NBT03_gp019;old_locus_tag=MPXV-M5312_HM12_Rivers-022 +NC_063383.1 RefSeq CDS 22497 23159 . - 0 ID=cds-YP_010377021.1;Parent=gene-NBT03_gp019;Dbxref=GenBank:YP_010377021.1,GeneID:72551435;Name=OPG038;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp026%3B NFkB inhibitor%3B similar to VACV-WR O2L and VACV-Cop M2L;gbkey=CDS;gene=OPG038;locus_tag=NBT03_gp019;product=NFkB inhibitor;protein_id=YP_010377021.1 +NC_063383.1 RefSeq gene 23264 24118 . - . ID=gene-NBT03_gp020;Dbxref=GeneID:72551436;Name=OPG039;gbkey=Gene;gene=OPG039;gene_biotype=protein_coding;locus_tag=NBT03_gp020;old_locus_tag=MPXV-M5312_HM12_Rivers-023 +NC_063383.1 RefSeq CDS 23264 24118 . - 0 ID=cds-YP_010377022.1;Parent=gene-NBT03_gp020;Dbxref=GenBank:YP_010377022.1,GeneID:72551436;Name=OPG039;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp027%3B host range%3B ankyrin-like%3B Ankyrin/NFkB inhibitor%3B similar to VACV-WR C1L and VACV-Cop K1L;gbkey=CDS;gene=OPG039;locus_tag=NBT03_gp020;product=Ankyrin-like protein (3);protein_id=YP_010377022.1 +NC_063383.1 RefSeq gene 24351 25478 . - . ID=gene-NBT03_gp021;Dbxref=GeneID:72551437;Name=OPG040;gbkey=Gene;gene=OPG040;gene_biotype=protein_coding;locus_tag=NBT03_gp021;old_locus_tag=MPXV-M5312_HM12_Rivers-024 +NC_063383.1 RefSeq CDS 24351 25478 . - 0 ID=cds-YP_010377023.1;Parent=gene-NBT03_gp021;Dbxref=GenBank:YP_010377023.1,GeneID:72551437;Name=OPG040;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp028%3B serine protease inhibitor-like%2C SPI-3%3B inhibition of the ability of infected cells to fuse%3B Serpin 1%2C2%2C3%3B similar to VACV-WR C2L and VACV-Cop K2L;gbkey=CDS;gene=OPG040;locus_tag=NBT03_gp021;product=Serpin;protein_id=YP_010377023.1 +NC_063383.1 RefSeq sequence_feature 25529 25767 . - . ID=id-NC_063383.1:25529..25767;exon_number=OPG041;gbkey=misc_feature;number=OPG041 +NC_063383.1 RefSeq gene 25823 27097 . - . ID=gene-NBT03_gp022;Dbxref=GeneID:72551438;Name=OPG042;gbkey=Gene;gene=OPG042;gene_biotype=protein_coding;locus_tag=NBT03_gp022;old_locus_tag=MPXV-M5312_HM12_Rivers-026 +NC_063383.1 RefSeq CDS 25823 27097 . - 0 ID=cds-YP_010377025.1;Parent=gene-NBT03_gp022;Dbxref=GenBank:YP_010377025.1,GeneID:72551438;Name=OPG042;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp030%3B phospholipase D-like%3B Phospholipase-D-like protein%3B similar to VACV-WR C4L and VACV-Cop K4L;gbkey=CDS;gene=OPG042;locus_tag=NBT03_gp022;product=Phospholipase-D-like protein;protein_id=YP_010377025.1 +NC_063383.1 RefSeq gene 27125 27955 . - . ID=gene-NBT03_gp023;Dbxref=GeneID:72551439;Name=OPG043;gbkey=Gene;gene=OPG043;gene_biotype=protein_coding;locus_tag=NBT03_gp023;old_locus_tag=MPXV-M5312_HM12_Rivers-027 +NC_063383.1 RefSeq CDS 27125 27955 . - 0 ID=cds-YP_010377026.1;Parent=gene-NBT03_gp023;Dbxref=GenBank:YP_010377026.1,GeneID:72551439;Name=OPG043;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp031%3B lysophospholipase-like%3B Monoglyceride lipase%3B similar to VACV-WR C5L and VACV-Cop K5L;gbkey=CDS;gene=OPG043;locus_tag=NBT03_gp023;product=Putative monoglyceride lipase;protein_id=YP_010377026.1 +NC_063383.1 RefSeq gene 28091 28540 . + . ID=gene-NBT03_gp024;Dbxref=GeneID:72551440;Name=OPG044;gbkey=Gene;gene=OPG044;gene_biotype=protein_coding;locus_tag=NBT03_gp024;old_locus_tag=MPXV-M5312_HM12_Rivers-028 +NC_063383.1 RefSeq CDS 28091 28540 . + 0 ID=cds-YP_010377027.1;Parent=gene-NBT03_gp024;Dbxref=GenBank:YP_010377027.1,GeneID:72551440;Name=OPG044;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp032%3B Putative tlr signaling inhibitor%3B Host immune response repressor%3B similar to VACV-WR C6R and VACV-Cop #K7R;gbkey=CDS;gene=OPG044;locus_tag=NBT03_gp024;product=Bcl-2-like protein;protein_id=YP_010377027.1 +NC_063383.1 RefSeq gene 28603 29262 . - . ID=gene-NBT03_gp025;Dbxref=GeneID:72551441;Name=OPG045;gbkey=Gene;gene=OPG045;gene_biotype=protein_coding;locus_tag=NBT03_gp025;old_locus_tag=MPXV-M5312_HM12_Rivers-029 +NC_063383.1 RefSeq CDS 28603 29262 . - 0 ID=cds-YP_010377028.1;Parent=gene-NBT03_gp025;Dbxref=GenBank:YP_010377028.1,GeneID:72551441;Name=OPG045;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp033%3B Caspase-9 (apoptosis) inhibitor (mitochondrial- associated)%3B similar to VACV-WR C7L and VACV-Cop F1L;gbkey=CDS;gene=OPG045;locus_tag=NBT03_gp025;product=Caspase-9 inhibitor;protein_id=YP_010377028.1 +NC_063383.1 RefSeq gene 29274 29729 . - . ID=gene-NBT03_gp026;Dbxref=GeneID:72551442;Name=OPG046;gbkey=Gene;gene=OPG046;gene_biotype=protein_coding;locus_tag=NBT03_gp026;old_locus_tag=MPXV-M5312_HM12_Rivers-030 +NC_063383.1 RefSeq CDS 29274 29729 . - 0 ID=cds-YP_010377029.1;Parent=gene-NBT03_gp026;Dbxref=GenBank:YP_010377029.1,GeneID:72551442;Name=OPG046;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp034%3B deoxyuridine triphosphatase%3B dUTPase%3B similar to VACV-WR C8L and VACV-Cop F2L;gbkey=CDS;gene=OPG046;locus_tag=NBT03_gp026;product=dUTPase;protein_id=YP_010377029.1 +NC_063383.1 RefSeq gene 29746 31194 . - . ID=gene-NBT03_gp027;Dbxref=GeneID:72551443;Name=OPG047;gbkey=Gene;gene=OPG047;gene_biotype=protein_coding;locus_tag=NBT03_gp027;old_locus_tag=MPXV-M5312_HM12_Rivers-031 +NC_063383.1 RefSeq CDS 29746 31194 . - 0 ID=cds-YP_010377030.1;Parent=gene-NBT03_gp027;Dbxref=GenBank:YP_010377030.1,GeneID:72551443;Name=OPG047;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp035%3B kelch-like%3B Kelch-like protein%3B similar to VACV-WR C9L and VACV-Cop F3L;gbkey=CDS;gene=OPG047;locus_tag=NBT03_gp027;product=Kelch-like protein (2);protein_id=YP_010377030.1 +NC_063383.1 RefSeq gene 31205 32164 . - . ID=gene-NBT03_gp028;Dbxref=GeneID:72551444;Name=OPG048;gbkey=Gene;gene=OPG048;gene_biotype=protein_coding;locus_tag=NBT03_gp028;old_locus_tag=MPXV-M5312_HM12_Rivers-032 +NC_063383.1 RefSeq CDS 31205 32164 . - 0 ID=cds-YP_010377031.1;Parent=gene-NBT03_gp028;Dbxref=GenBank:YP_010377031.1,GeneID:72551444;Name=OPG048;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp036%3B Ribonucleotide reductase small subunit%2C R2%3B similar to VACV-WR C10L and VACV-Cop F4L;gbkey=CDS;gene=OPG048;locus_tag=NBT03_gp028;product=Ribonucleotide reductase small subunit;protein_id=YP_010377031.1 +NC_063383.1 RefSeq gene 32195 33151 . - . ID=gene-NBT03_gp029;Dbxref=GeneID:72551445;Name=OPG049;gbkey=Gene;gene=OPG049;gene_biotype=protein_coding;locus_tag=NBT03_gp029;old_locus_tag=MPXV-M5312_HM12_Rivers-033 +NC_063383.1 RefSeq CDS 32195 33151 . - 0 ID=cds-YP_010377032.1;Parent=gene-NBT03_gp029;Dbxref=GenBank:YP_010377032.1,GeneID:72551445;Name=OPG049;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp037%3B 36kDa major membrane protein%3B similar to VACV-WR C11L and VACV-Cop F5L;gbkey=CDS;gene=OPG049;locus_tag=NBT03_gp029;product=Telomere-binding protein I6 (1);protein_id=YP_010377032.1 +NC_063383.1 RefSeq gene 33181 33408 . - . ID=gene-NBT03_gp030;Dbxref=GeneID:72551446;Name=OPG050;gbkey=Gene;gene=OPG050;gene_biotype=protein_coding;locus_tag=NBT03_gp030;old_locus_tag=MPXV-M5312_HM12_Rivers-034 +NC_063383.1 RefSeq CDS 33181 33408 . - 0 ID=cds-YP_010377033.1;Parent=gene-NBT03_gp030;Dbxref=GenBank:YP_010377033.1,GeneID:72551446;Name=OPG050;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp038%3B Hypothetical protein%3B similar to VACV-WR C12L and VACV-Cop F6L;gbkey=CDS;gene=OPG050;locus_tag=NBT03_gp030;product=CPXV053 protein;protein_id=YP_010377033.1 +NC_063383.1 RefSeq gene 33425 33649 . - . ID=gene-NBT03_gp031;Dbxref=GeneID:72551447;Name=OPG051;gbkey=Gene;gene=OPG051;gene_biotype=protein_coding;locus_tag=NBT03_gp031;old_locus_tag=MPXV-M5312_HM12_Rivers-035 +NC_063383.1 RefSeq CDS 33425 33649 . - 0 ID=cds-YP_010377034.1;Parent=gene-NBT03_gp031;Dbxref=GenBank:YP_010377034.1,GeneID:72551447;Name=OPG051;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp039%3B Hypothetical protein%3B similar to VACV-WR C13L and VACV-Cop F7L;gbkey=CDS;gene=OPG051;locus_tag=NBT03_gp031;product=CPXV054 protein;protein_id=YP_010377034.1 +NC_063383.1 RefSeq gene 33801 33995 . - . ID=gene-NBT03_gp032;Dbxref=GeneID:72551448;Name=OPG052;gbkey=Gene;gene=OPG052;gene_biotype=protein_coding;locus_tag=NBT03_gp032;old_locus_tag=MPXV-M5312_HM12_Rivers-036 +NC_063383.1 RefSeq CDS 33801 33995 . - 0 ID=cds-YP_010377035.1;Parent=gene-NBT03_gp032;Dbxref=GenBank:YP_010377035.1,GeneID:72551448;Name=OPG052;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp040%3B Cytoplasmic protein%3B similar to VACV-WR C14L and VACV-Cop F8L;gbkey=CDS;gene=OPG052;locus_tag=NBT03_gp032;product=Cytoplasmic protein;protein_id=YP_010377035.1 +NC_063383.1 RefSeq gene 34052 34690 . - . ID=gene-NBT03_gp033;Dbxref=GeneID:72551449;Name=OPG053;gbkey=Gene;gene=OPG053;gene_biotype=protein_coding;locus_tag=NBT03_gp033;old_locus_tag=MPXV-M5312_HM12_Rivers-037 +NC_063383.1 RefSeq CDS 34052 34690 . - 0 ID=cds-YP_010377036.1;Parent=gene-NBT03_gp033;Dbxref=GenBank:YP_010377036.1,GeneID:72551449;Name=OPG053;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp041%3B S-S bond formation pathway protein substrate%3B similar to VACV-WR C15L and VACV-Cop F9L;gbkey=CDS;gene=OPG053;locus_tag=NBT03_gp033;product=IMV membrane protein L1R;protein_id=YP_010377036.1 +NC_063383.1 RefSeq gene 34677 35996 . - . ID=gene-NBT03_gp034;Dbxref=GeneID:72551450;Name=OPG054;gbkey=Gene;gene=OPG054;gene_biotype=protein_coding;locus_tag=NBT03_gp034;old_locus_tag=MPXV-M5312_HM12_Rivers-038 +NC_063383.1 RefSeq CDS 34677 35996 . - 0 ID=cds-YP_010377037.1;Parent=gene-NBT03_gp034;Dbxref=GenBank:YP_010377037.1,GeneID:72551450;Name=OPG054;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp042%3B serine%3B Essential Ser/Thr kinase morph%3B similar to VACV-WR C16L and VACV-Cop F10L;gbkey=CDS;gene=OPG054;locus_tag=NBT03_gp034;product=Serine/threonine-protein kinase;protein_id=YP_010377037.1 +NC_063383.1 RefSeq gene 36019 37083 . - . ID=gene-NBT03_gp035;Dbxref=GeneID:72551451;Name=OPG055;gbkey=Gene;gene=OPG055;gene_biotype=protein_coding;locus_tag=NBT03_gp035;old_locus_tag=MPXV-M5312_HM12_Rivers-039 +NC_063383.1 RefSeq CDS 36019 37083 . - 0 ID=cds-YP_010377038.1;Parent=gene-NBT03_gp035;Dbxref=GenBank:YP_010377038.1,GeneID:72551451;Name=OPG055;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp043%3B RhoA signalling inhibitor%2C virus release protein%3B MC018%3B similar to VACV-WR C17L and VACV-Cop F11L;gbkey=CDS;gene=OPG055;locus_tag=NBT03_gp035;product=Protein F11;protein_id=YP_010377038.1 +NC_063383.1 RefSeq gene 37127 39034 . - . ID=gene-NBT03_gp036;Dbxref=GeneID:72551452;Name=OPG056;gbkey=Gene;gene=OPG056;gene_biotype=protein_coding;locus_tag=NBT03_gp036;old_locus_tag=MPXV-M5312_HM12_Rivers-040 +NC_063383.1 RefSeq CDS 37127 39034 . - 0 ID=cds-YP_010377039.1;Parent=gene-NBT03_gp036;Dbxref=GenBank:YP_010377039.1,GeneID:72551452;Name=OPG056;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp044%3B actin tail formation%3B EEV maturation protein%3B similar to VACV-WR C18L and VACV-Cop F12L;gbkey=CDS;gene=OPG056;locus_tag=NBT03_gp036;product=EEV maturation protein;protein_id=YP_010377039.1 +NC_063383.1 RefSeq gene 39077 40195 . - . ID=gene-NBT03_gp037;Dbxref=GeneID:72551453;Name=OPG057;gbkey=Gene;gene=OPG057;gene_biotype=protein_coding;locus_tag=NBT03_gp037;old_locus_tag=MPXV-M5312_HM12_Rivers-041 +NC_063383.1 RefSeq CDS 39077 40195 . - 0 ID=cds-YP_010377040.1;Parent=gene-NBT03_gp037;Dbxref=GenBank:YP_010377040.1,GeneID:72551453;Name=OPG057;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp045%3B major envelope antigen of EEV%3B wrapping of IMV to form IEV%3B phospholipase D-like%3B Palmitylated EEV membrane glycoprotein%3B similar to VACV-WR C19L and VACV-Cop F13L;gbkey=CDS;gene=OPG057;locus_tag=NBT03_gp037;product=Palmytilated EEV membrane protein;protein_id=YP_010377040.1 +NC_063383.1 RefSeq gene 40213 40434 . - . ID=gene-NBT03_gp038;Dbxref=GeneID:72551454;Name=OPG058;gbkey=Gene;gene=OPG058;gene_biotype=protein_coding;locus_tag=NBT03_gp038;old_locus_tag=MPXV-M5312_HM12_Rivers-042 +NC_063383.1 RefSeq CDS 40213 40434 . - 0 ID=cds-YP_010377041.1;Parent=gene-NBT03_gp038;Dbxref=GenBank:YP_010377041.1,GeneID:72551454;Name=OPG058;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp046%3B similar to VACV-WR C20L and VACV-Cop F14L;gbkey=CDS;gene=OPG058;locus_tag=NBT03_gp038;product=Protein F14 (1);protein_id=YP_010377041.1 +NC_063383.1 RefSeq gene 40484 40633 . - . ID=gene-NBT03_gp039;Dbxref=GeneID:72551455;Name=OPG059;gbkey=Gene;gene=OPG059;gene_biotype=protein_coding;locus_tag=NBT03_gp039;old_locus_tag=MPXV-M5312_HM12_Rivers-043 +NC_063383.1 RefSeq CDS 40484 40633 . - 0 ID=cds-YP_010377042.1;Parent=gene-NBT03_gp039;Dbxref=GenBank:YP_010377042.1,GeneID:72551455;Name=OPG059;Note=Taxonomic breadth: poxvirinae%3B IMV protein%3B C20.5L%3B similar to VACV-CopF14.5L;gbkey=CDS;gene=OPG059;locus_tag=NBT03_gp039;product=Cytochrome C oxidase;protein_id=YP_010377042.1 +NC_063383.1 RefSeq gene 40706 41182 . - . ID=gene-NBT03_gp040;Dbxref=GeneID:72551456;Name=OPG060;gbkey=Gene;gene=OPG060;gene_biotype=protein_coding;locus_tag=NBT03_gp040;old_locus_tag=MPXV-M5312_HM12_Rivers-044 +NC_063383.1 RefSeq CDS 40706 41182 . - 0 ID=cds-YP_010377043.1;Parent=gene-NBT03_gp040;Dbxref=GenBank:YP_010377043.1,GeneID:72551456;Name=OPG060;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp047%3B Unknown conserved protein%3B similar to VACV-WR C21L and VACV-Cop F15L;gbkey=CDS;gene=OPG060;locus_tag=NBT03_gp040;product=Protein F15;protein_id=YP_010377043.1 +NC_063383.1 RefSeq gene 41189 41884 . - . ID=gene-NBT03_gp041;Dbxref=GeneID:72551457;Name=OPG061;gbkey=Gene;gene=OPG061;gene_biotype=protein_coding;locus_tag=NBT03_gp041;old_locus_tag=MPXV-M5312_HM12_Rivers-045 +NC_063383.1 RefSeq CDS 41189 41884 . - 0 ID=cds-YP_010377044.1;Parent=gene-NBT03_gp041;Dbxref=GenBank:YP_010377044.1,GeneID:72551457;Name=OPG061;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp048%3B Non-functional Serine Recombinase%3B similar to VACV-WR C22L and VACV-Cop F16L;gbkey=CDS;gene=OPG061;locus_tag=NBT03_gp041;product=Protein F16 (1);protein_id=YP_010377044.1 +NC_063383.1 RefSeq gene 41947 42252 . + . ID=gene-NBT03_gp042;Dbxref=GeneID:72551458;Name=OPG062;gbkey=Gene;gene=OPG062;gene_biotype=protein_coding;locus_tag=NBT03_gp042;old_locus_tag=MPXV-M5312_HM12_Rivers-046 +NC_063383.1 RefSeq CDS 41947 42252 . + 0 ID=cds-YP_010377045.1;Parent=gene-NBT03_gp042;Dbxref=GenBank:YP_010377045.1,GeneID:72551458;Name=OPG062;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp049%3B virion core DNA-binding phosphoprotein (VP11)%3B mTOR antagonist%3B similar to VACV-WR C23R and VACV-Cop F17R;gbkey=CDS;gene=OPG062;locus_tag=NBT03_gp042;product=DNA-binding phosphoprotein (1);protein_id=YP_010377045.1 +NC_063383.1 RefSeq gene 42249 43688 . - . ID=gene-NBT03_gp043;Dbxref=GeneID:72551459;Name=OPG063;gbkey=Gene;gene=OPG063;gene_biotype=protein_coding;locus_tag=NBT03_gp043;old_locus_tag=MPXV-M5312_HM12_Rivers-047 +NC_063383.1 RefSeq CDS 42249 43688 . - 0 ID=cds-YP_010377046.1;Parent=gene-NBT03_gp043;Dbxref=GenBank:YP_010377046.1,GeneID:72551459;Name=OPG063;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp050%3B poly-A polymerase%2C Poly (A) polymerase catalytic subunit (VP55)%3B similar to VACV-WR F1L and VACV-Cop E1L;gbkey=CDS;gene=OPG063;locus_tag=NBT03_gp043;product=Poly(A) polymerase catalytic subunit (3);protein_id=YP_010377046.1 +NC_063383.1 RefSeq gene 43685 45898 . - . ID=gene-NBT03_gp044;Dbxref=GeneID:72551460;Name=OPG064;gbkey=Gene;gene=OPG064;gene_biotype=protein_coding;locus_tag=NBT03_gp044;old_locus_tag=MPXV-M5312_HM12_Rivers-048 +NC_063383.1 RefSeq CDS 43685 45898 . - 0 ID=cds-YP_010377047.1;Parent=gene-NBT03_gp044;Dbxref=GenBank:YP_010377047.1,GeneID:72551460;Name=OPG064;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp051%3B IEV morphogenesis%3B similar to VACV-WR F2L and VACV-Cop E2L;gbkey=CDS;gene=OPG064;locus_tag=NBT03_gp044;product=Iev morphogenesis protein;protein_id=YP_010377047.1 +NC_063383.1 RefSeq gene 46022 46483 . - . ID=gene-NBT03_gp045;Dbxref=GeneID:72551461;Name=OPG065;gbkey=Gene;gene=OPG065;gene_biotype=protein_coding;locus_tag=NBT03_gp045;old_locus_tag=MPXV-M5312_HM12_Rivers-049 +NC_063383.1 RefSeq CDS 46022 46483 . - 0 ID=cds-YP_010377048.1;Parent=gene-NBT03_gp045;Dbxref=GenBank:YP_010377048.1,GeneID:72551461;Name=OPG065;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp052%3B interferon resistance factor%3B two forms (25 kDa and 19 kDa) of the dsRNA-binding protein%3B inhibition of dsRNA-dependent protein kinase and 2-5A-synthet%3B dsRNA-binding protein%2C IFN resistance/PKR inhibitor (Z-DNA binding)%3B start of ORF is missing approx. 37 AA compared to CPXVs%3B similar to VACV-WR F3L and VACV-Cop E3L;gbkey=CDS;gene=OPG065;locus_tag=NBT03_gp045;product=Double-stranded RNA binding protein;protein_id=YP_010377048.1 +NC_063383.1 RefSeq gene 46649 47428 . - . ID=gene-NBT03_gp046;Dbxref=GeneID:72551462;Name=OPG066;gbkey=Gene;gene=OPG066;gene_biotype=protein_coding;locus_tag=NBT03_gp046;old_locus_tag=MPXV-M5312_HM12_Rivers-050 +NC_063383.1 RefSeq CDS 46649 47428 . - 0 ID=cds-YP_010377049.1;Parent=gene-NBT03_gp046;Dbxref=GenBank:YP_010377049.1,GeneID:72551462;Name=OPG066;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp053%3B RNA polymerase 30 kDa subunit (RPO30)%3B simultaneously intermediate stage promoter-specific transcription factor%2C VITF-1%3B similar to VACV-WR F4L and VACV-Cop E4L;gbkey=CDS;gene=OPG066;locus_tag=NBT03_gp046;product=DNA-directed RNA polymerase 30 kDa polypeptide;protein_id=YP_010377049.1 +NC_063383.1 RefSeq sequence_feature 47525 48062 . + . ID=id-NC_063383.1:47525..48062;exon_number=OPG067;gbkey=misc_feature;number=OPG067 +NC_063383.1 RefSeq gene 48201 49904 . + . ID=gene-NBT03_gp047;Dbxref=GeneID:72551463;Name=OPG068;gbkey=Gene;gene=OPG068;gene_biotype=protein_coding;locus_tag=NBT03_gp047;old_locus_tag=MPXV-M5312_HM12_Rivers-052 +NC_063383.1 RefSeq CDS 48201 49904 . + 0 ID=cds-YP_010377051.1;Parent=gene-NBT03_gp047;Dbxref=GenBank:YP_010377051.1,GeneID:72551463;Name=OPG068;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp054%3B Virion protein%3B similar to VACV-WR F5R and VACV-Cop E6R;gbkey=CDS;gene=OPG068;locus_tag=NBT03_gp047;product=IMV membrane protein E6;protein_id=YP_010377051.1 +NC_063383.1 RefSeq gene 49986 50486 . + . ID=gene-NBT03_gp048;Dbxref=GeneID:72551464;Name=OPG069;gbkey=Gene;gene=OPG069;gene_biotype=protein_coding;locus_tag=NBT03_gp048;old_locus_tag=MPXV-M5312_HM12_Rivers-053 +NC_063383.1 RefSeq CDS 49986 50486 . + 0 ID=cds-YP_010377052.1;Parent=gene-NBT03_gp048;Dbxref=GenBank:YP_010377052.1,GeneID:72551464;Name=OPG069;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp055%3B soluble myristylated protein%3B similar to VACV-WR F6R and VACV-Cop E7R;gbkey=CDS;gene=OPG069;locus_tag=NBT03_gp048;product=Myristoylated protein E7;protein_id=YP_010377052.1 +NC_063383.1 RefSeq gene 50590 51411 . + . ID=gene-NBT03_gp049;Dbxref=GeneID:72551465;Name=OPG070;gbkey=Gene;gene=OPG070;gene_biotype=protein_coding;locus_tag=NBT03_gp049;old_locus_tag=MPXV-M5312_HM12_Rivers-054 +NC_063383.1 RefSeq CDS 50590 51411 . + 0 ID=cds-YP_010377053.1;Parent=gene-NBT03_gp049;Dbxref=GenBank:YP_010377053.1,GeneID:72551465;Name=OPG070;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp056%3B ER-localized membrane protein%2C virion core protein%3B similar to VACV-WR F7R and VACV-Cop E8R;gbkey=CDS;gene=OPG070;locus_tag=NBT03_gp049;product=Membrane protein E8;protein_id=YP_010377053.1 +NC_063383.1 RefSeq gene 51418 54438 . - . ID=gene-NBT03_gp050;Dbxref=GeneID:72551466;Name=OPG071;gbkey=Gene;gene=OPG071;gene_biotype=protein_coding;locus_tag=NBT03_gp050;old_locus_tag=MPXV-M5312_HM12_Rivers-055 +NC_063383.1 RefSeq CDS 51418 54438 . - 0 ID=cds-YP_010377054.1;Parent=gene-NBT03_gp050;Dbxref=GenBank:YP_010377054.1,GeneID:72551466;Name=OPG071;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp057%3B DNA polymerase%2C catalytic subunit%3B similar to VACV-WR F8L and VACV-Cop E9L;gbkey=CDS;gene=OPG071;locus_tag=NBT03_gp050;product=DNA polymerase (2);protein_id=YP_010377054.1 +NC_063383.1 RefSeq gene 54470 54757 . + . ID=gene-NBT03_gp051;Dbxref=GeneID:72551467;Name=OPG072;gbkey=Gene;gene=OPG072;gene_biotype=protein_coding;locus_tag=NBT03_gp051;old_locus_tag=MPXV-M5312_HM12_Rivers-056 +NC_063383.1 RefSeq CDS 54470 54757 . + 0 ID=cds-YP_010377055.1;Parent=gene-NBT03_gp051;Dbxref=GenBank:YP_010377055.1,GeneID:72551467;Name=OPG072;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp058%3B protein disulfide bond-forming enzyme%3B Sulfhydryl oxidase (FAD-linked)%3B similar to VACV-WR F9R and VACV-Cop E10R;gbkey=CDS;gene=OPG072;locus_tag=NBT03_gp051;product=Sulfhydryl oxidase;protein_id=YP_010377055.1 +NC_063383.1 RefSeq gene 54752 55141 . - . ID=gene-NBT03_gp052;Dbxref=GeneID:72551468;Name=OPG073;gbkey=Gene;gene=OPG073;gene_biotype=protein_coding;locus_tag=NBT03_gp052;old_locus_tag=MPXV-M5312_HM12_Rivers-057 +NC_063383.1 RefSeq CDS 54752 55141 . - 0 ID=cds-YP_010377056.1;Parent=gene-NBT03_gp052;Dbxref=GenBank:YP_010377056.1,GeneID:72551468;Name=OPG073;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp059%3B virion core protein%3B similar to VACV-WR F10L and VACV-Cop E11L;gbkey=CDS;gene=OPG073;locus_tag=NBT03_gp052;product=Virion core protein E11;protein_id=YP_010377056.1 +NC_063383.1 RefSeq gene 55128 57125 . - . ID=gene-NBT03_gp053;Dbxref=GeneID:72551469;Name=OPG074;gbkey=Gene;gene=OPG074;gene_biotype=protein_coding;locus_tag=NBT03_gp053;old_locus_tag=MPXV-M5312_HM12_Rivers-058 +NC_063383.1 RefSeq CDS 55128 57125 . - 0 ID=cds-YP_010377057.1;Parent=gene-NBT03_gp053;Dbxref=GenBank:YP_010377057.1,GeneID:72551469;Name=OPG074;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp060%3B Membrane protein%3B similar to VACV-WR Q1L and VACV-Cop O1L;gbkey=CDS;gene=OPG074;locus_tag=NBT03_gp053;product=Iev morphogenesis protein;protein_id=YP_010377057.1 +NC_063383.1 RefSeq gene 57172 57498 . - . ID=gene-NBT03_gp054;Dbxref=GeneID:72551470;Name=OPG075;gbkey=Gene;gene=OPG075;gene_biotype=protein_coding;locus_tag=NBT03_gp054;old_locus_tag=MPXV-M5312_HM12_Rivers-059 +NC_063383.1 RefSeq CDS 57172 57498 . - 0 ID=cds-YP_010377058.1;Parent=gene-NBT03_gp054;Dbxref=GenBank:YP_010377058.1,GeneID:72551470;Name=OPG075;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp061%3B virion-associated glutaredoxin%3B glutaredoxin 1%3B similar to VACV-WR Q2L and VACV-Cop O2L;gbkey=CDS;gene=OPG075;locus_tag=NBT03_gp054;product=Glutaredoxin-1;protein_id=YP_010377058.1 +NC_063383.1 RefSeq gene 57523 57630 . - . ID=gene-NBT03_gp055;Dbxref=GeneID:72551471;Name=OPG076;gbkey=Gene;gene=OPG076;gene_biotype=protein_coding;locus_tag=NBT03_gp055 +NC_063383.1 RefSeq CDS 57523 57630 . - 0 ID=cds-YP_010377183.1;Parent=gene-NBT03_gp055;Dbxref=GenBank:YP_010377183.1,GeneID:72551471;Name=OPG076;gbkey=CDS;gene=OPG076;locus_tag=NBT03_gp055;product=MV membrane EFC component;protein_id=YP_010377183.1 +NC_063383.1 RefSeq gene 57645 58583 . - . ID=gene-NBT03_gp056;Dbxref=GeneID:72551472;Name=OPG077;gbkey=Gene;gene=OPG077;gene_biotype=protein_coding;locus_tag=NBT03_gp056;old_locus_tag=MPXV-M5312_HM12_Rivers-060 +NC_063383.1 RefSeq CDS 57645 58583 . - 0 ID=cds-YP_010377059.1;Parent=gene-NBT03_gp056;Dbxref=GenBank:YP_010377059.1,GeneID:72551472;Name=OPG077;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp062%3B virosomal protein essential for virus multiplication%3B DNA-binding core protein%3B similar to VACV-WR I1L and VACV-Cop I1L;gbkey=CDS;gene=OPG077;locus_tag=NBT03_gp056;product=Telomere-binding protein I1;protein_id=YP_010377059.1 +NC_063383.1 RefSeq gene 58590 58811 . - . ID=gene-NBT03_gp057;Dbxref=GeneID:72551473;Name=OPG078;gbkey=Gene;gene=OPG078;gene_biotype=protein_coding;locus_tag=NBT03_gp057;old_locus_tag=MPXV-M5312_HM12_Rivers-061 +NC_063383.1 RefSeq CDS 58590 58811 . - 0 ID=cds-YP_010377060.1;Parent=gene-NBT03_gp057;Dbxref=GenBank:YP_010377060.1,GeneID:72551473;Name=OPG078;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp063%3B IMV membrane protein%3B similar to VACV-WR I2L and VACV-Cop I2L;gbkey=CDS;gene=OPG078;locus_tag=NBT03_gp057;product=IMV membrane protein I2;protein_id=YP_010377060.1 +NC_063383.1 RefSeq gene 58812 59621 . - . ID=gene-NBT03_gp058;Dbxref=GeneID:72551474;Name=OPG079;gbkey=Gene;gene=OPG079;gene_biotype=protein_coding;locus_tag=NBT03_gp058;old_locus_tag=MPXV-M5312_HM12_Rivers-062 +NC_063383.1 RefSeq CDS 58812 59621 . - 0 ID=cds-YP_010377061.1;Parent=gene-NBT03_gp058;Dbxref=GenBank:YP_010377061.1,GeneID:72551474;Name=OPG079;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp064%3B virosomal ssDNA-binding phosphoprotein%3B interacts with R2 subunit of ribonucleotide reductase%3B similar to VACV-WR I3L and VACV-Cop I3L;gbkey=CDS;gene=OPG079;locus_tag=NBT03_gp058;product=DNA-binding phosphoprotein (2);protein_id=YP_010377061.1 +NC_063383.1 RefSeq gene 59703 62018 . - . ID=gene-NBT03_gp059;Dbxref=GeneID:72551475;Name=OPG080;gbkey=Gene;gene=OPG080;gene_biotype=protein_coding;locus_tag=NBT03_gp059;old_locus_tag=MPXV-M5312_HM12_Rivers-063 +NC_063383.1 RefSeq CDS 59703 62018 . - 0 ID=cds-YP_010377062.1;Parent=gene-NBT03_gp059;Dbxref=GenBank:YP_010377062.1,GeneID:72551475;Name=OPG080;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp065%3B ribonucleotide reductase%2C large subunit%2C R1%3B similar to VACV-WR I4L and VACV-Cop I4L;gbkey=CDS;gene=OPG080;locus_tag=NBT03_gp059;product=Ribonucleoside-diphosphate reductase (2);protein_id=YP_010377062.1 +NC_063383.1 RefSeq gene 62046 62285 . - . ID=gene-NBT03_gp060;Dbxref=GeneID:72551476;Name=OPG081;gbkey=Gene;gene=OPG081;gene_biotype=protein_coding;locus_tag=NBT03_gp060;old_locus_tag=MPXV-M5312_HM12_Rivers-064 +NC_063383.1 RefSeq CDS 62046 62285 . - 0 ID=cds-YP_010377063.1;Parent=gene-NBT03_gp060;Dbxref=GenBank:YP_010377063.1,GeneID:72551476;Name=OPG081;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp066%3B IMV surface membrane protein%2C VP13%3B similar to VACV-WR I5L and VACV-Cop I5L;gbkey=CDS;gene=OPG081;locus_tag=NBT03_gp060;product=IMV membrane protein I5;protein_id=YP_010377063.1 +NC_063383.1 RefSeq gene 62304 63452 . - . ID=gene-NBT03_gp061;Dbxref=GeneID:72551477;Name=OPG082;gbkey=Gene;gene=OPG082;gene_biotype=protein_coding;locus_tag=NBT03_gp061;old_locus_tag=MPXV-M5312_HM12_Rivers-065 +NC_063383.1 RefSeq CDS 62304 63452 . - 0 ID=cds-YP_010377064.1;Parent=gene-NBT03_gp061;Dbxref=GenBank:YP_010377064.1,GeneID:72551477;Name=OPG082;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp067%3B Telomere-binding protein%3B similar to VACV-WR I6L and VACV-Cop I6L;gbkey=CDS;gene=OPG082;locus_tag=NBT03_gp061;product=Telomere-binding protein;protein_id=YP_010377064.1 +NC_063383.1 RefSeq gene 63445 64716 . - . ID=gene-NBT03_gp062;Dbxref=GeneID:72551478;Name=OPG083;gbkey=Gene;gene=OPG083;gene_biotype=protein_coding;locus_tag=NBT03_gp062;old_locus_tag=MPXV-M5312_HM12_Rivers-066 +NC_063383.1 RefSeq CDS 63445 64716 . - 0 ID=cds-YP_010377065.1;Parent=gene-NBT03_gp062;Dbxref=GenBank:YP_010377065.1,GeneID:72551478;Name=OPG083;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp068%3B virion core protein%3B similar to DNA topoisomerase II%3B Virion core cysteine protease%3B similar to VACV-WR I7L and VACV-Cop I7L;gbkey=CDS;gene=OPG083;locus_tag=NBT03_gp062;product=Viral core cysteine proteinase;protein_id=YP_010377065.1 +NC_063383.1 RefSeq gene 64722 66752 . + . ID=gene-NBT03_gp063;Dbxref=GeneID:72551479;Name=OPG084;gbkey=Gene;gene=OPG084;gene_biotype=protein_coding;locus_tag=NBT03_gp063;old_locus_tag=MPXV-M5312_HM12_Rivers-067 +NC_063383.1 RefSeq CDS 64722 66752 . + 0 ID=cds-YP_010377066.1;Parent=gene-NBT03_gp063;Dbxref=GenBank:YP_010377066.1,GeneID:72551479;Name=OPG084;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp069%3B nucleoside triphosphate phosphohydrolase II%2C NPH-II%3B DNA and RNA helicase%3B DExH-NPH-II domain%3B similar to VACV-WR I8R and VACV-Cop I8R;gbkey=CDS;gene=OPG084;locus_tag=NBT03_gp063;product=RNA helicase NPH-II (2);protein_id=YP_010377066.1 +NC_063383.1 RefSeq gene 66756 68531 . - . ID=gene-NBT03_gp064;Dbxref=GeneID:72551480;Name=OPG085;gbkey=Gene;gene=OPG085;gene_biotype=protein_coding;locus_tag=NBT03_gp064;old_locus_tag=MPXV-M5312_HM12_Rivers-068 +NC_063383.1 RefSeq CDS 66756 68531 . - 0 ID=cds-YP_010377067.1;Parent=gene-NBT03_gp064;Dbxref=GenBank:YP_010377067.1,GeneID:72551480;Name=OPG085;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp070%3B proteinase%3B Metalloprotease%3B similar to VACV-WR G1L and VACV-Cop G1L;gbkey=CDS;gene=OPG085;locus_tag=NBT03_gp064;product=Metalloendopeptidase;protein_id=YP_010377067.1 +NC_063383.1 RefSeq gene 68528 68863 . - . ID=gene-NBT03_gp065;Dbxref=GeneID:72551481;Name=OPG086;gbkey=Gene;gene=OPG086;gene_biotype=protein_coding;locus_tag=NBT03_gp065;old_locus_tag=MPXV-M5312_HM12_Rivers-069 +NC_063383.1 RefSeq CDS 68528 68863 . - 0 ID=cds-YP_010377068.1;Parent=gene-NBT03_gp065;Dbxref=GenBank:YP_010377068.1,GeneID:72551481;Name=OPG086;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp071%3B Entry/fusion complex component%3B similar to VACV-WR G2L and VACV-Cop G3L;gbkey=CDS;gene=OPG086;locus_tag=NBT03_gp065;product=Entry/fusion complex component;protein_id=YP_010377068.1 +NC_063383.1 RefSeq gene 68857 69519 . + . ID=gene-NBT03_gp066;Dbxref=GeneID:72551482;Name=OPG087;gbkey=Gene;gene=OPG087;gene_biotype=protein_coding;locus_tag=NBT03_gp066;old_locus_tag=MPXV-M5312_HM12_Rivers-070 +NC_063383.1 RefSeq CDS 68857 69519 . + 0 ID=cds-YP_010377069.1;Parent=gene-NBT03_gp066;Dbxref=GenBank:YP_010377069.1,GeneID:72551482;Name=OPG087;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp072%3B VLTF (late transcription elongation factor)%3B similar to VACV-WR G3R and VACV-Cop G2R;gbkey=CDS;gene=OPG087;locus_tag=NBT03_gp066;product=Late transcription elongation factor;protein_id=YP_010377069.1 +NC_063383.1 RefSeq gene 69489 69863 . - . ID=gene-NBT03_gp067;Dbxref=GeneID:72551483;Name=OPG088;gbkey=Gene;gene=OPG088;gene_biotype=protein_coding;locus_tag=NBT03_gp067;old_locus_tag=MPXV-M5312_HM12_Rivers-071 +NC_063383.1 RefSeq CDS 69489 69863 . - 0 ID=cds-YP_010377070.1;Parent=gene-NBT03_gp067;Dbxref=GenBank:YP_010377070.1,GeneID:72551483;Name=OPG088;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp073%3B virion-associated glutaredoxin%3B Glutaredoxin-like protein%3B similar to VACV-WR G4L and VACV-Cop G4L;gbkey=CDS;gene=OPG088;locus_tag=NBT03_gp067;product=Glutaredoxin-2;protein_id=YP_010377070.1 +NC_063383.1 RefSeq gene 69866 71170 . + . ID=gene-NBT03_gp068;Dbxref=GeneID:72551484;Name=OPG089;gbkey=Gene;gene=OPG089;gene_biotype=protein_coding;locus_tag=NBT03_gp068;old_locus_tag=MPXV-M5312_HM12_Rivers-072 +NC_063383.1 RefSeq CDS 69866 71170 . + 0 ID=cds-YP_010377071.1;Parent=gene-NBT03_gp068;Dbxref=GenBank:YP_010377071.1,GeneID:72551484;Name=OPG089;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp074%3B FEN1-like nuclease%3B similar to VACV-WR G5R and VACV-Cop G5R;gbkey=CDS;gene=OPG089;locus_tag=NBT03_gp068;product=FEN1-like nuclease;protein_id=YP_010377071.1 +NC_063383.1 RefSeq gene 71179 71370 . + . ID=gene-NBT03_gp069;Dbxref=GeneID:72551485;Name=OPG090;gbkey=Gene;gene=OPG090;gene_biotype=protein_coding;locus_tag=NBT03_gp069;old_locus_tag=MPXV-M5312_HM12_Rivers-073 +NC_063383.1 RefSeq CDS 71179 71370 . + 0 ID=cds-YP_010377072.1;Parent=gene-NBT03_gp069;Dbxref=GenBank:YP_010377072.1,GeneID:72551485;Name=OPG090;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp075%3B RNA polymerase subunit%2C 7 kDa subunit (RPO7)%3B similar to VACV-WR G6R and VACV-Cop G5.5R;gbkey=CDS;gene=OPG090;locus_tag=NBT03_gp069;product=DNA-directed RNA polymerase 7 kDa subunit;protein_id=YP_010377072.1 +NC_063383.1 RefSeq gene 71370 71867 . + . ID=gene-NBT03_gp070;Dbxref=GeneID:72551486;Name=OPG091;gbkey=Gene;gene=OPG091;gene_biotype=protein_coding;locus_tag=NBT03_gp070;old_locus_tag=MPXV-M5312_HM12_Rivers-074 +NC_063383.1 RefSeq CDS 71370 71867 . + 0 ID=cds-YP_010377073.1;Parent=gene-NBT03_gp070;Dbxref=GenBank:YP_010377073.1,GeneID:72551486;Name=OPG091;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp076%3B NLPc/P60 superfamily protein%3B similar to VACV-WR G7R and VACV-Cop G6R;gbkey=CDS;gene=OPG091;locus_tag=NBT03_gp070;product=Nlpc/p60 superfamily protein;protein_id=YP_010377073.1 +NC_063383.1 RefSeq gene 71832 72947 . - . ID=gene-NBT03_gp071;Dbxref=GeneID:72551487;Name=OPG092;gbkey=Gene;gene=OPG092;gene_biotype=protein_coding;locus_tag=NBT03_gp071;old_locus_tag=MPXV-M5312_HM12_Rivers-075 +NC_063383.1 RefSeq CDS 71832 72947 . - 0 ID=cds-YP_010377074.1;Parent=gene-NBT03_gp071;Dbxref=GenBank:YP_010377074.1,GeneID:72551487;Name=OPG092;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp077%3B virion protein%3B Virion phosphoprotein%2C early morphogenesis%3B similar to VACV-WR G8L and VACV-Cop G7L;gbkey=CDS;gene=OPG092;locus_tag=NBT03_gp071;product=Assembly protein G7;protein_id=YP_010377074.1 +NC_063383.1 RefSeq gene 72978 73760 . + . ID=gene-NBT03_gp072;Dbxref=GeneID:72551488;Name=OPG093;gbkey=Gene;gene=OPG093;gene_biotype=protein_coding;locus_tag=NBT03_gp072;old_locus_tag=MPXV-M5312_HM12_Rivers-076 +NC_063383.1 RefSeq CDS 72978 73760 . + 0 ID=cds-YP_010377075.1;Parent=gene-NBT03_gp072;Dbxref=GenBank:YP_010377075.1,GeneID:72551488;Name=OPG093;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp078%3B late gene transcription factor%2C VLTF-1%3B similar to VACV-WR G9R and VACV-Cop G8R;gbkey=CDS;gene=OPG093;locus_tag=NBT03_gp072;product=Late transcription factor VLTF-1;protein_id=YP_010377075.1 +NC_063383.1 RefSeq gene 73780 74802 . + . ID=gene-NBT03_gp073;Dbxref=GeneID:72551489;Name=OPG094;gbkey=Gene;gene=OPG094;gene_biotype=protein_coding;locus_tag=NBT03_gp073;old_locus_tag=MPXV-M5312_HM12_Rivers-077 +NC_063383.1 RefSeq CDS 73780 74802 . + 0 ID=cds-YP_010377076.1;Parent=gene-NBT03_gp073;Dbxref=GenBank:YP_010377076.1,GeneID:72551489;Name=OPG094;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp079%3B myristylated protein%3B Entry/fusion complex component%2C myristylprotein%3B similar to VACV-WR G10R and VACV-Cop G9R;gbkey=CDS;gene=OPG094;locus_tag=NBT03_gp073;product=Myristylated protein;protein_id=YP_010377076.1 +NC_063383.1 RefSeq gene 74803 75555 . + . ID=gene-NBT03_gp074;Dbxref=GeneID:72551490;Name=OPG095;gbkey=Gene;gene=OPG095;gene_biotype=protein_coding;locus_tag=NBT03_gp074;old_locus_tag=MPXV-M5312_HM12_Rivers-078 +NC_063383.1 RefSeq CDS 74803 75555 . + 0 ID=cds-YP_010377077.1;Parent=gene-NBT03_gp074;Dbxref=GenBank:YP_010377077.1,GeneID:72551490;Name=OPG095;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp080%3B myristylated IMV surface membrane protein%3B similar to VACV-WR M1R and VACV-Cop L1R;gbkey=CDS;gene=OPG095;locus_tag=NBT03_gp074;product=IMV membrane protein L1R;protein_id=YP_010377077.1 +NC_063383.1 RefSeq gene 75587 75865 . + . ID=gene-NBT03_gp075;Dbxref=GeneID:72551491;Name=OPG096;gbkey=Gene;gene=OPG096;gene_biotype=protein_coding;locus_tag=NBT03_gp075;old_locus_tag=MPXV-M5312_HM12_Rivers-079 +NC_063383.1 RefSeq CDS 75587 75865 . + 0 ID=cds-YP_010377078.1;Parent=gene-NBT03_gp075;Dbxref=GenBank:YP_010377078.1,GeneID:72551491;Name=OPG096;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp081%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR M2R and VACV-Cop L2R;gbkey=CDS;gene=OPG096;locus_tag=NBT03_gp075;product=Crescent membrane and immature virion formation protein;protein_id=YP_010377078.1 +NC_063383.1 RefSeq gene 75841 76875 . - . ID=gene-NBT03_gp076;Dbxref=GeneID:72551492;Name=OPG097;gbkey=Gene;gene=OPG097;gene_biotype=protein_coding;locus_tag=NBT03_gp076;old_locus_tag=MPXV-M5312_HM12_Rivers-080 +NC_063383.1 RefSeq CDS 75841 76875 . - 0 ID=cds-YP_010377079.1;Parent=gene-NBT03_gp076;Dbxref=GenBank:YP_010377079.1,GeneID:72551492;Name=OPG097;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp082%3B Internal virion protein%3B similar to VACV-WR M3L and VACV-Cop L3L;gbkey=CDS;gene=OPG097;locus_tag=NBT03_gp076;product=Internal virion L3/FP4 protein;protein_id=YP_010377079.1 +NC_063383.1 RefSeq gene 76900 77655 . + . ID=gene-NBT03_gp077;Dbxref=GeneID:72551493;Name=OPG098;gbkey=Gene;gene=OPG098;gene_biotype=protein_coding;locus_tag=NBT03_gp077;old_locus_tag=MPXV-M5312_HM12_Rivers-081 +NC_063383.1 RefSeq CDS 76900 77655 . + 0 ID=cds-YP_010377080.1;Parent=gene-NBT03_gp077;Dbxref=GenBank:YP_010377080.1,GeneID:72551493;Name=OPG098;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp083%3B virion core protein vp8%3B stimulation of I8R helicase activity%3B ss/dsDNA binding protein (VP8)%3B similar to VACV-WR M4R and VACV-Cop L4R;gbkey=CDS;gene=OPG098;locus_tag=NBT03_gp077;product=Nucleic acid binding protein VP8/L4R;protein_id=YP_010377080.1 +NC_063383.1 RefSeq gene 77665 78051 . + . ID=gene-NBT03_gp078;Dbxref=GeneID:72551494;Name=OPG099;gbkey=Gene;gene=OPG099;gene_biotype=protein_coding;locus_tag=NBT03_gp078;old_locus_tag=MPXV-M5312_HM12_Rivers-082 +NC_063383.1 RefSeq CDS 77665 78051 . + 0 ID=cds-YP_010377081.1;Parent=gene-NBT03_gp078;Dbxref=GenBank:YP_010377081.1,GeneID:72551494;Name=OPG099;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp084%3B Entry and Fusion IMV protein%3B similar to VACV-WR M5R and VACV-Cop L5R;gbkey=CDS;gene=OPG099;locus_tag=NBT03_gp078;product=Membrane protein CL5;protein_id=YP_010377081.1 +NC_063383.1 RefSeq gene 78008 78466 . + . ID=gene-NBT03_gp079;Dbxref=GeneID:72551495;Name=OPG100;gbkey=Gene;gene=OPG100;gene_biotype=protein_coding;locus_tag=NBT03_gp079;old_locus_tag=MPXV-M5312_HM12_Rivers-083 +NC_063383.1 RefSeq CDS 78008 78466 . + 0 ID=cds-YP_010377082.1;Parent=gene-NBT03_gp079;Dbxref=GenBank:YP_010377082.1,GeneID:72551495;Name=OPG100;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp085%3B Virion morph%3B similar to VACV-WR L1R and VACV-Cop J1R;gbkey=CDS;gene=OPG100;locus_tag=NBT03_gp079;product=IMV membrane protein J1;protein_id=YP_010377082.1 +NC_063383.1 RefSeq gene 78486 79019 . + . ID=gene-NBT03_gp080;Dbxref=GeneID:72551496;Name=OPG101;gbkey=Gene;gene=OPG101;gene_biotype=protein_coding;locus_tag=NBT03_gp080;old_locus_tag=MPXV-M5312_HM12_Rivers-084 +NC_063383.1 RefSeq CDS 78486 79019 . + 0 ID=cds-YP_010377083.1;Parent=gene-NBT03_gp080;Dbxref=GenBank:YP_010377083.1,GeneID:72551496;Name=OPG101;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp086%3B thymidine kinase%3B similar to VACV-WR L2R and VACV-Cop J2R;gbkey=CDS;gene=OPG101;locus_tag=NBT03_gp080;product=Thymidine kinase;protein_id=YP_010377083.1 +NC_063383.1 RefSeq gene 79085 80086 . + . ID=gene-NBT03_gp081;Dbxref=GeneID:72551497;Name=OPG102;gbkey=Gene;gene=OPG102;gene_biotype=protein_coding;locus_tag=NBT03_gp081;old_locus_tag=MPXV-M5312_HM12_Rivers-085 +NC_063383.1 RefSeq CDS 79085 80086 . + 0 ID=cds-YP_010377084.1;Parent=gene-NBT03_gp081;Dbxref=GenBank:YP_010377084.1,GeneID:72551497;Name=OPG102;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp087%3B poly-A polymerase%2C stimulatory subunit%2C simultaneously cap-specific mRNA (nucleoside-O2'-)-methyltransferase%3B Poly (A) polymerase small subunit (VP39)%3B similar to VACV-WR L3R and VACV-Cop J3R;gbkey=CDS;gene=OPG102;locus_tag=NBT03_gp081;product=Cap-specific mRNA;protein_id=YP_010377084.1 +NC_063383.1 RefSeq gene 80001 80558 . + . ID=gene-NBT03_gp082;Dbxref=GeneID:72551498;Name=OPG103;gbkey=Gene;gene=OPG103;gene_biotype=protein_coding;locus_tag=NBT03_gp082;old_locus_tag=MPXV-M5312_HM12_Rivers-086 +NC_063383.1 RefSeq CDS 80001 80558 . + 0 ID=cds-YP_010377085.1;Parent=gene-NBT03_gp082;Dbxref=GenBank:YP_010377085.1,GeneID:72551498;Name=OPG103;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp088%3B RNA polymerase%2C 22 kDa subunit (RPO22)%3B similar to VACV-WR L4R and VACV-Cop J4R;gbkey=CDS;gene=OPG103;locus_tag=NBT03_gp082;product=DNA-directed RNA polymerase subunit;protein_id=YP_010377085.1 +NC_063383.1 RefSeq gene 80618 81019 . - . ID=gene-NBT03_gp083;Dbxref=GeneID:72551499;Name=OPG104;gbkey=Gene;gene=OPG104;gene_biotype=protein_coding;locus_tag=NBT03_gp083;old_locus_tag=MPXV-M5312_HM12_Rivers-087 +NC_063383.1 RefSeq CDS 80618 81019 . - 0 ID=cds-YP_010377086.1;Parent=gene-NBT03_gp083;Dbxref=GenBank:YP_010377086.1,GeneID:72551499;Name=OPG104;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp089%3B essential for virus multiplication%3B IMV membrane protein%3B similar to VACV-WR L5L and VACV-Cop J5L;gbkey=CDS;gene=OPG104;locus_tag=NBT03_gp083;product=Myristylated protein;protein_id=YP_010377086.1 +NC_063383.1 RefSeq gene 81126 84986 . + . ID=gene-NBT03_gp084;Dbxref=GeneID:72551500;Name=OPG105;gbkey=Gene;gene=OPG105;gene_biotype=protein_coding;locus_tag=NBT03_gp084;old_locus_tag=MPXV-M5312_HM12_Rivers-088 +NC_063383.1 RefSeq CDS 81126 84986 . + 0 ID=cds-YP_010377087.1;Parent=gene-NBT03_gp084;Dbxref=GenBank:YP_010377087.1,GeneID:72551500;Name=OPG105;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp090%3B RNA polymerase%2C 147 kDa subunit (RPO147)%3B similar to VACV-WR L6R and VACV-Cop J6R;gbkey=CDS;gene=OPG105;locus_tag=NBT03_gp084;product=DNA-dependent RNA polymerase subunit rpo147;protein_id=YP_010377087.1 +NC_063383.1 RefSeq gene 84983 85498 . - . ID=gene-NBT03_gp085;Dbxref=GeneID:72551501;Name=OPG106;gbkey=Gene;gene=OPG106;gene_biotype=protein_coding;locus_tag=NBT03_gp085;old_locus_tag=MPXV-M5312_HM12_Rivers-089 +NC_063383.1 RefSeq CDS 84983 85498 . - 0 ID=cds-YP_010377088.1;Parent=gene-NBT03_gp085;Dbxref=GenBank:YP_010377088.1,GeneID:72551501;Name=OPG106;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp091%3B tyrosine%3B Tyr/Ser phosphatase%2C IFN-gamma inhibitor%3B similar to VACV-WR H1L and VACV-Cop H1L;gbkey=CDS;gene=OPG106;locus_tag=NBT03_gp085;product=Tyr/ser protein phosphatase;protein_id=YP_010377088.1 +NC_063383.1 RefSeq gene 85512 86081 . + . ID=gene-NBT03_gp086;Dbxref=GeneID:72551502;Name=OPG107;gbkey=Gene;gene=OPG107;gene_biotype=protein_coding;locus_tag=NBT03_gp086;old_locus_tag=MPXV-M5312_HM12_Rivers-090 +NC_063383.1 RefSeq CDS 85512 86081 . + 0 ID=cds-YP_010377089.1;Parent=gene-NBT03_gp086;Dbxref=GenBank:YP_010377089.1,GeneID:72551502;Name=OPG107;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp092%3B IMV membrane protein%3B similar to VACV-WR H2R and VACV-Cop H2R;gbkey=CDS;gene=OPG107;locus_tag=NBT03_gp086;product=Entry-fusion complex essential component;protein_id=YP_010377089.1 +NC_063383.1 RefSeq gene 86085 87059 . - . ID=gene-NBT03_gp087;Dbxref=GeneID:72551503;Name=OPG108;gbkey=Gene;gene=OPG108;gene_biotype=protein_coding;locus_tag=NBT03_gp087;old_locus_tag=MPXV-M5312_HM12_Rivers-091 +NC_063383.1 RefSeq CDS 86085 87059 . - 0 ID=cds-YP_010377090.1;Parent=gene-NBT03_gp087;Dbxref=GenBank:YP_010377090.1,GeneID:72551503;Name=OPG108;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp093%3B IMV surface membrane protein%3B IMV heparin binding surface protein%3B similar to VACV-WR H3L and VACV-Cop H3L;gbkey=CDS;gene=OPG108;locus_tag=NBT03_gp087;product=IMV heparin binding surface protein;protein_id=YP_010377090.1 +NC_063383.1 RefSeq gene 87060 89447 . - . ID=gene-NBT03_gp088;Dbxref=GeneID:72551504;Name=OPG109;gbkey=Gene;gene=OPG109;gene_biotype=protein_coding;locus_tag=NBT03_gp088;old_locus_tag=MPXV-M5312_HM12_Rivers-092 +NC_063383.1 RefSeq CDS 87060 89447 . - 0 ID=cds-YP_010377091.1;Parent=gene-NBT03_gp088;Dbxref=GenBank:YP_010377091.1,GeneID:72551504;Name=OPG109;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp094%3B virion core RNA polymerase-associated protein%2C RAP94%3B similar to VACV-WR H4L and VACV-Cop H4L;gbkey=CDS;gene=OPG109;locus_tag=NBT03_gp088;product=RNA polymerase-associated transcription-specificity factor RAP94;protein_id=YP_010377091.1 +NC_063383.1 RefSeq gene 89632 90264 . + . ID=gene-NBT03_gp089;Dbxref=GeneID:72551505;Name=OPG110;gbkey=Gene;gene=OPG110;gene_biotype=protein_coding;locus_tag=NBT03_gp089;old_locus_tag=MPXV-M5312_HM12_Rivers-093 +NC_063383.1 RefSeq CDS 89632 90264 . + 0 ID=cds-YP_010377092.1;Parent=gene-NBT03_gp089;Dbxref=GenBank:YP_010377092.1,GeneID:72551505;Name=OPG110;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp095%3B virosome-associated late gene transcription factor%2C VLTF-4%3B Ca2+-binding motif%3B similar to VACV-WR H5R and VACV-Cop H5R;gbkey=CDS;gene=OPG110;locus_tag=NBT03_gp089;product=Late transcription factor VLTF-4 (1);protein_id=YP_010377092.1 +NC_063383.1 RefSeq gene 90265 91209 . + . ID=gene-NBT03_gp090;Dbxref=GeneID:72551506;Name=OPG111;gbkey=Gene;gene=OPG111;gene_biotype=protein_coding;locus_tag=NBT03_gp090;old_locus_tag=MPXV-M5312_HM12_Rivers-094 +NC_063383.1 RefSeq CDS 90265 91209 . + 0 ID=cds-YP_010377093.1;Parent=gene-NBT03_gp090;Dbxref=GenBank:YP_010377093.1,GeneID:72551506;Name=OPG111;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp096%3B DNA topoisomerase type I%3B similar to VACV-WR H6R and VACV-Cop H6R;gbkey=CDS;gene=OPG111;locus_tag=NBT03_gp090;product=DNA topoisomerase type I;protein_id=YP_010377093.1 +NC_063383.1 RefSeq gene 91247 91687 . + . ID=gene-NBT03_gp091;Dbxref=GeneID:72551507;Name=OPG112;gbkey=Gene;gene=OPG112;gene_biotype=protein_coding;locus_tag=NBT03_gp091;old_locus_tag=MPXV-M5312_HM12_Rivers-095 +NC_063383.1 RefSeq CDS 91247 91687 . + 0 ID=cds-YP_010377094.1;Parent=gene-NBT03_gp091;Dbxref=GenBank:YP_010377094.1,GeneID:72551507;Name=OPG112;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp097%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR H7R and VACV-Cop H7R;gbkey=CDS;gene=OPG112;locus_tag=NBT03_gp091;product=Late protein H7;protein_id=YP_010377094.1 +NC_063383.1 RefSeq gene 91731 94268 . + . ID=gene-NBT03_gp092;Dbxref=GeneID:72551508;Name=OPG113;gbkey=Gene;gene=OPG113;gene_biotype=protein_coding;locus_tag=NBT03_gp092;old_locus_tag=MPXV-M5312_HM12_Rivers-096 +NC_063383.1 RefSeq CDS 91731 94268 . + 0 ID=cds-YP_010377095.1;Parent=gene-NBT03_gp092;Dbxref=GenBank:YP_010377095.1,GeneID:72551508;Name=OPG113;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp098%3B mRNA capping enzyme%2C large subunit%3B RNA 5' triphosphatase and RNA guanylyl transferase activities%3B similar to VACV-WR E1R and VACV-Cop D1R;gbkey=CDS;gene=OPG113;locus_tag=NBT03_gp092;product=mRNA capping enzyme large subunit;protein_id=YP_010377095.1 +NC_063383.1 RefSeq gene 94227 94667 . - . ID=gene-NBT03_gp093;Dbxref=GeneID:72551509;Name=OPG114;gbkey=Gene;gene=OPG114;gene_biotype=protein_coding;locus_tag=NBT03_gp093;old_locus_tag=MPXV-M5312_HM12_Rivers-097 +NC_063383.1 RefSeq CDS 94227 94667 . - 0 ID=cds-YP_010377096.1;Parent=gene-NBT03_gp093;Dbxref=GenBank:YP_010377096.1,GeneID:72551509;Name=OPG114;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp099%3B virion core protein%3B similar to VACV-WR E2L and VACV-Cop D2L;gbkey=CDS;gene=OPG114;locus_tag=NBT03_gp093;product=Virion protein D2;protein_id=YP_010377096.1 +NC_063383.1 RefSeq gene 94660 95361 . + . ID=gene-NBT03_gp094;Dbxref=GeneID:72551510;Name=OPG115;gbkey=Gene;gene=OPG115;gene_biotype=protein_coding;locus_tag=NBT03_gp094;old_locus_tag=MPXV-M5312_HM12_Rivers-098 +NC_063383.1 RefSeq CDS 94660 95361 . + 0 ID=cds-YP_010377097.1;Parent=gene-NBT03_gp094;Dbxref=GenBank:YP_010377097.1,GeneID:72551510;Name=OPG115;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp100%3B virion core protein%3B similar to VACV-WR E3R and VACV-Cop D3R;gbkey=CDS;gene=OPG115;locus_tag=NBT03_gp094;product=Virion core protein D3;protein_id=YP_010377097.1 +NC_063383.1 RefSeq gene 95361 96017 . + . ID=gene-NBT03_gp095;Dbxref=GeneID:72551511;Name=OPG116;gbkey=Gene;gene=OPG116;gene_biotype=protein_coding;locus_tag=NBT03_gp095;old_locus_tag=MPXV-M5312_HM12_Rivers-099 +NC_063383.1 RefSeq CDS 95361 96017 . + 0 ID=cds-YP_010377098.1;Parent=gene-NBT03_gp095;Dbxref=GenBank:YP_010377098.1,GeneID:72551511;Name=OPG116;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp101%3B uracil DNA glycosylase%3B DNA polymerase processivity factor%3B similar to VACV-WR E4R and VACV-Cop D4R;gbkey=CDS;gene=OPG116;locus_tag=NBT03_gp095;product=Uracil DNA glycosylase superfamily;protein_id=YP_010377098.1 +NC_063383.1 RefSeq gene 96049 98406 . + . ID=gene-NBT03_gp096;Dbxref=GeneID:72551512;Name=OPG117;gbkey=Gene;gene=OPG117;gene_biotype=protein_coding;locus_tag=NBT03_gp096;old_locus_tag=MPXV-M5312_HM12_Rivers-100 +NC_063383.1 RefSeq CDS 96049 98406 . + 0 ID=cds-YP_010377099.1;Parent=gene-NBT03_gp096;Dbxref=GenBank:YP_010377099.1,GeneID:72551512;Name=OPG117;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp102%3B nucleic acid-independent nucleoside triphosphatase%3B NTPase%2C DNA primase%3B similar to VACV-WR E5R and VACV-Cop D5R;gbkey=CDS;gene=OPG117;locus_tag=NBT03_gp096;product=NTPase (1);protein_id=YP_010377099.1 +NC_063383.1 RefSeq gene 98446 100359 . + . ID=gene-NBT03_gp097;Dbxref=GeneID:72551513;Name=OPG118;gbkey=Gene;gene=OPG118;gene_biotype=protein_coding;locus_tag=NBT03_gp097;old_locus_tag=MPXV-M5312_HM12_Rivers-101 +NC_063383.1 RefSeq CDS 98446 100359 . + 0 ID=cds-YP_010377100.1;Parent=gene-NBT03_gp097;Dbxref=GenBank:YP_010377100.1,GeneID:72551513;Name=OPG118;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp103%3B early transcription factor%2C small subunit%2C VETF-s%3B Morphogenesis%3B similar to VACV-WR E6R and VACV-Cop D6R;gbkey=CDS;gene=OPG118;locus_tag=NBT03_gp097;product=Early transcription factor 70 kDa subunit;protein_id=YP_010377100.1 +NC_063383.1 RefSeq gene 100386 100871 . + . ID=gene-NBT03_gp098;Dbxref=GeneID:72551514;Name=OPG119;gbkey=Gene;gene=OPG119;gene_biotype=protein_coding;locus_tag=NBT03_gp098;old_locus_tag=MPXV-M5312_HM12_Rivers-102 +NC_063383.1 RefSeq CDS 100386 100871 . + 0 ID=cds-YP_010377101.1;Parent=gene-NBT03_gp098;Dbxref=GenBank:YP_010377101.1,GeneID:72551514;Name=OPG119;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp104%3B RNA polymerase%2C 18 kDa subunit (RPO18)%3B similar to VACV-WR E7R and VACV-Cop D7R;gbkey=CDS;gene=OPG119;locus_tag=NBT03_gp098;product=RNA polymerase subunit RPO18;protein_id=YP_010377101.1 +NC_063383.1 RefSeq gene 100834 101748 . - . ID=gene-NBT03_gp099;Dbxref=GeneID:72551515;Name=OPG120;gbkey=Gene;gene=OPG120;gene_biotype=protein_coding;locus_tag=NBT03_gp099;old_locus_tag=MPXV-M5312_HM12_Rivers-103 +NC_063383.1 RefSeq CDS 100834 101748 . - 0 ID=cds-YP_010377102.1;Parent=gene-NBT03_gp099;Dbxref=GenBank:YP_010377102.1,GeneID:72551515;Name=OPG120;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp105%3B IMV surface membrane 32 kDa protein%3B binding to cell surface chondroitin sulfate%3B IMV adsorption to cell surface%3B GAG-binding IMV membrane protein%3B similar to VACV-WR E8L and VACV-Cop D8L;gbkey=CDS;gene=OPG120;locus_tag=NBT03_gp099;product=Carbonic anhydrase;protein_id=YP_010377102.1 +NC_063383.1 RefSeq gene 101790 102431 . + . ID=gene-NBT03_gp100;Dbxref=GeneID:72551516;Name=OPG121;gbkey=Gene;gene=OPG121;gene_biotype=protein_coding;locus_tag=NBT03_gp100;old_locus_tag=MPXV-M5312_HM12_Rivers-104 +NC_063383.1 RefSeq CDS 101790 102431 . + 0 ID=cds-YP_010377103.1;Parent=gene-NBT03_gp100;Dbxref=GenBank:YP_010377103.1,GeneID:72551516;Name=OPG121;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp106%3B Mut-like%3B mRNA decapping enzyme%3B similar to VACV-WR E9R and VACV-Cop D9R;gbkey=CDS;gene=OPG121;locus_tag=NBT03_gp100;product=NUDIX domain protein;protein_id=YP_010377103.1 +NC_063383.1 RefSeq gene 102428 103174 . + . ID=gene-NBT03_gp101;Dbxref=GeneID:72551517;Name=OPG122;gbkey=Gene;gene=OPG122;gene_biotype=protein_coding;locus_tag=NBT03_gp101;old_locus_tag=MPXV-M5312_HM12_Rivers-105 +NC_063383.1 RefSeq CDS 102428 103174 . + 0 ID=cds-YP_010377104.1;Parent=gene-NBT03_gp101;Dbxref=GenBank:YP_010377104.1,GeneID:72551517;Name=OPG122;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp107%3B down regulation of gene expression%3B Mut-like%3B mRNA decapping enzyme%3B similar to VACV-WR E10R and VACV-Cop D10R;gbkey=CDS;gene=OPG122;locus_tag=NBT03_gp101;product=MutT motif protein;protein_id=YP_010377104.1 +NC_063383.1 RefSeq gene 103175 105070 . - . ID=gene-NBT03_gp102;Dbxref=GeneID:72551518;Name=OPG123;gbkey=Gene;gene=OPG123;gene_biotype=protein_coding;locus_tag=NBT03_gp102;old_locus_tag=MPXV-M5312_HM12_Rivers-106 +NC_063383.1 RefSeq CDS 103175 105070 . - 0 ID=cds-YP_010377105.1;Parent=gene-NBT03_gp102;Dbxref=GenBank:YP_010377105.1,GeneID:72551518;Name=OPG123;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp108%3B nucleoside triphosphate phosphohydrolase I%2C NPH I%3B DNA-dependent ATPase%3B early gene transcription termination factor%3B similar to VACV-WR E11L and VACV-Cop D11L;gbkey=CDS;gene=OPG123;locus_tag=NBT03_gp102;product=Nucleoside triphosphatase I;protein_id=YP_010377105.1 +NC_063383.1 RefSeq gene 105105 105968 . - . ID=gene-NBT03_gp103;Dbxref=GeneID:72551519;Name=OPG124;gbkey=Gene;gene=OPG124;gene_biotype=protein_coding;locus_tag=NBT03_gp103;old_locus_tag=MPXV-M5312_HM12_Rivers-107 +NC_063383.1 RefSeq CDS 105105 105968 . - 0 ID=cds-YP_010377106.1;Parent=gene-NBT03_gp103;Dbxref=GenBank:YP_010377106.1,GeneID:72551519;Name=OPG124;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp109%3B mRNA capping enzyme small subunit%3B mRNA (guanine-N7-)-methyl-transferase%3B transcription initiation factor%3B similar to VACV-WR E12L and VACV-Cop D12L;gbkey=CDS;gene=OPG124;locus_tag=NBT03_gp103;product=mRNA capping enzyme small subunit;protein_id=YP_010377106.1 +NC_063383.1 RefSeq gene 105999 107654 . - . ID=gene-NBT03_gp104;Dbxref=GeneID:72551520;Name=OPG125;gbkey=Gene;gene=OPG125;gene_biotype=protein_coding;locus_tag=NBT03_gp104;old_locus_tag=MPXV-M5312_HM12_Rivers-108 +NC_063383.1 RefSeq CDS 105999 107654 . - 0 ID=cds-YP_010377107.1;Parent=gene-NBT03_gp104;Dbxref=GenBank:YP_010377107.1,GeneID:72551520;Name=OPG125;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp110%3B protein needed for the formation of immature IMV surface membrane%3B Trimeric virion coat protein (rifampicin res)%3B similar to VACV-WR E13L and VACV-Cop D13L;gbkey=CDS;gene=OPG125;locus_tag=NBT03_gp104;product=Rifampicin resistance protein;protein_id=YP_010377107.1 +NC_063383.1 RefSeq gene 107678 108130 . - . ID=gene-NBT03_gp105;Dbxref=GeneID:72551521;Name=OPG126;gbkey=Gene;gene=OPG126;gene_biotype=protein_coding;locus_tag=NBT03_gp105;old_locus_tag=MPXV-M5312_HM12_Rivers-109 +NC_063383.1 RefSeq CDS 107678 108130 . - 0 ID=cds-YP_010377108.1;Parent=gene-NBT03_gp105;Dbxref=GenBank:YP_010377108.1,GeneID:72551521;Name=OPG126;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp111%3B late gene transcription factor%2C VLTF-2%3B similar to VACV-WR A1L and VACV-Cop A1L;gbkey=CDS;gene=OPG126;locus_tag=NBT03_gp105;product=Late transcription factor VLTF-2 (2);protein_id=YP_010377108.1 +NC_063383.1 RefSeq gene 108151 108825 . - . ID=gene-NBT03_gp106;Dbxref=GeneID:72551522;Name=OPG127;gbkey=Gene;gene=OPG127;gene_biotype=protein_coding;locus_tag=NBT03_gp106;old_locus_tag=MPXV-M5312_HM12_Rivers-110 +NC_063383.1 RefSeq CDS 108151 108825 . - 0 ID=cds-YP_010377109.1;Parent=gene-NBT03_gp106;Dbxref=GenBank:YP_010377109.1,GeneID:72551522;Name=OPG127;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp112%3B late gene transcription factor%2C VLTF-3%3B zinc binding%3B similar to VACV-WR A2L and VACV-Cop A2L;gbkey=CDS;gene=OPG127;locus_tag=NBT03_gp106;product=Late transcription factor VLTF-3 (1);protein_id=YP_010377109.1 +NC_063383.1 RefSeq gene 108822 109055 . - . ID=gene-NBT03_gp107;Dbxref=GeneID:72551523;Name=OPG128;gbkey=Gene;gene=OPG128;gene_biotype=protein_coding;locus_tag=NBT03_gp107;old_locus_tag=MPXV-M5312_HM12_Rivers-111 +NC_063383.1 RefSeq CDS 108822 109055 . - 0 ID=cds-YP_010377110.1;Parent=gene-NBT03_gp107;Dbxref=GenBank:YP_010377110.1,GeneID:72551523;Name=OPG128;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp113%3B S-S bond formation pathway protein%3B similar to VACV-WR A3L and VACV-Cop A2.5L;gbkey=CDS;gene=OPG128;locus_tag=NBT03_gp107;product=S-S bond formation pathway protein;protein_id=YP_010377110.1 +NC_063383.1 RefSeq gene 109070 111004 . - . ID=gene-NBT03_gp108;Dbxref=GeneID:72551524;Name=OPG129;gbkey=Gene;gene=OPG129;gene_biotype=protein_coding;locus_tag=NBT03_gp108;old_locus_tag=MPXV-M5312_HM12_Rivers-112 +NC_063383.1 RefSeq CDS 109070 111004 . - 0 ID=cds-YP_010377111.1;Parent=gene-NBT03_gp108;Dbxref=GenBank:YP_010377111.1,GeneID:72551524;Name=OPG129;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp114%3B major virion core protein p4b%3B P4b precursor%3B similar to VACV-WR A4L and VACV-Cop A3L;gbkey=CDS;gene=OPG129;locus_tag=NBT03_gp108;product=Virion core protein P4b;protein_id=YP_010377111.1 +NC_063383.1 RefSeq gene 111057 111902 . - . ID=gene-NBT03_gp109;Dbxref=GeneID:72551525;Name=OPG130;gbkey=Gene;gene=OPG130;gene_biotype=protein_coding;locus_tag=NBT03_gp109;old_locus_tag=MPXV-M5312_HM12_Rivers-113 +NC_063383.1 RefSeq CDS 111057 111902 . - 0 ID=cds-YP_010377112.1;Parent=gene-NBT03_gp109;Dbxref=GenBank:YP_010377112.1,GeneID:72551525;Name=OPG130;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp115%3B 39 kDa immunodominant virion core protein needed for the progression of IV to infectious IMV%3B 39kDa virion core protein%3B similar to VACV-WR A5L and VACV-Cop A4L;gbkey=CDS;gene=OPG130;locus_tag=NBT03_gp109;product=A5L protein-like;protein_id=YP_010377112.1 +NC_063383.1 RefSeq gene 111940 112425 . + . ID=gene-NBT03_gp110;Dbxref=GeneID:72551526;Name=OPG131;gbkey=Gene;gene=OPG131;gene_biotype=protein_coding;locus_tag=NBT03_gp110;old_locus_tag=MPXV-M5312_HM12_Rivers-114 +NC_063383.1 RefSeq CDS 111940 112425 . + 0 ID=cds-YP_010377113.1;Parent=gene-NBT03_gp110;Dbxref=GenBank:YP_010377113.1,GeneID:72551526;Name=OPG131;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp116%3B precursor of RNA polymerase 22 kDa and 21 kDa%3B RNA polymerase subunit (RPO19)%3B similar to VACV-WR A6R and VACV-Cop A5R;gbkey=CDS;gene=OPG131;locus_tag=NBT03_gp110;product=DNA-directed RNA polymerase 19 kDa subunit;protein_id=YP_010377113.1 +NC_063383.1 RefSeq gene 112422 113540 . - . ID=gene-NBT03_gp111;Dbxref=GeneID:72551527;Name=OPG132;gbkey=Gene;gene=OPG132;gene_biotype=protein_coding;locus_tag=NBT03_gp111;old_locus_tag=MPXV-M5312_HM12_Rivers-115 +NC_063383.1 RefSeq CDS 112422 113540 . - 0 ID=cds-YP_010377114.1;Parent=gene-NBT03_gp111;Dbxref=GenBank:YP_010377114.1,GeneID:72551527;Name=OPG132;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp117%3B Viral membrane assembly proteins (VMAP)%2C core protein%3B similar to VACV-WR A7L and VACV-Cop A6L;gbkey=CDS;gene=OPG132;locus_tag=NBT03_gp111;product=Virion morphogenesis protein;protein_id=YP_010377114.1 +NC_063383.1 RefSeq gene 113564 115696 . - . ID=gene-NBT03_gp112;Dbxref=GeneID:72551528;Name=OPG133;gbkey=Gene;gene=OPG133;gene_biotype=protein_coding;locus_tag=NBT03_gp112;old_locus_tag=MPXV-M5312_HM12_Rivers-116 +NC_063383.1 RefSeq CDS 113564 115696 . - 0 ID=cds-YP_010377115.1;Parent=gene-NBT03_gp112;Dbxref=GenBank:YP_010377115.1,GeneID:72551528;Name=OPG133;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp118%3B early transcription factor%2C large subunit%2C VETF-L%3B needed for morphogenesis of the virion core%3B similar to VACV-WR A8L and VACV-Cop A7L;gbkey=CDS;gene=OPG133;locus_tag=NBT03_gp112;product=Early transcription factor 82 kDa subunit;protein_id=YP_010377115.1 +NC_063383.1 RefSeq gene 115750 116628 . + . ID=gene-NBT03_gp113;Dbxref=GeneID:72551529;Name=OPG134;gbkey=Gene;gene=OPG134;gene_biotype=protein_coding;locus_tag=NBT03_gp113;old_locus_tag=MPXV-M5312_HM12_Rivers-117 +NC_063383.1 RefSeq CDS 115750 116628 . + 0 ID=cds-YP_010377116.1;Parent=gene-NBT03_gp113;Dbxref=GenBank:YP_010377116.1,GeneID:72551529;Name=OPG134;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp119%3B intermediate transcription factor%2C VITF-3 34kda subunit%2C 34 kDa%3B similar to VACV-WR A9R and VACV-Cop A8R;gbkey=CDS;gene=OPG134;locus_tag=NBT03_gp113;product=Intermediate transcription factor VITF-3 (1);protein_id=YP_010377116.1 +NC_063383.1 RefSeq gene 116609 116911 . - . ID=gene-NBT03_gp114;Dbxref=GeneID:72551530;Name=OPG135;gbkey=Gene;gene=OPG135;gene_biotype=protein_coding;locus_tag=NBT03_gp114;old_locus_tag=MPXV-M5312_HM12_Rivers-118 +NC_063383.1 RefSeq CDS 116609 116911 . - 0 ID=cds-YP_010377117.1;Parent=gene-NBT03_gp114;Dbxref=GenBank:YP_010377117.1,GeneID:72551530;Name=OPG135;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp120%3B Viral membrane associated%2C early morphogenesis protein%3B similar to VACV-WR A10L and VACV-Cop A9L;gbkey=CDS;gene=OPG135;locus_tag=NBT03_gp114;product=IMV membrane protein A9;protein_id=YP_010377117.1 +NC_063383.1 RefSeq gene 116912 119587 . - . ID=gene-NBT03_gp115;Dbxref=GeneID:72551531;Name=OPG136;gbkey=Gene;gene=OPG136;gene_biotype=protein_coding;locus_tag=NBT03_gp115;old_locus_tag=MPXV-M5312_HM12_Rivers-119 +NC_063383.1 RefSeq CDS 116912 119587 . - 0 ID=cds-YP_010377118.1;Parent=gene-NBT03_gp115;Dbxref=GenBank:YP_010377118.1,GeneID:72551531;Name=OPG136;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp121%3B major virion core protein p4a%3B P4a precursor%3B similar to VACV-WR A11L and VACV-Cop A10L;gbkey=CDS;gene=OPG136;locus_tag=NBT03_gp115;product=Virion core protein P4a;protein_id=YP_010377118.1 +NC_063383.1 RefSeq gene 119602 120558 . + . ID=gene-NBT03_gp116;Dbxref=GeneID:72551532;Name=OPG137;gbkey=Gene;gene=OPG137;gene_biotype=protein_coding;locus_tag=NBT03_gp116;old_locus_tag=MPXV-M5312_HM12_Rivers-120 +NC_063383.1 RefSeq CDS 119602 120558 . + 0 ID=cds-YP_010377119.1;Parent=gene-NBT03_gp116;Dbxref=GenBank:YP_010377119.1,GeneID:72551532;Name=OPG137;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp122%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR A12R and VACV-Cop A11R;gbkey=CDS;gene=OPG137;locus_tag=NBT03_gp116;product=Viral membrane formation protein;protein_id=YP_010377119.1 +NC_063383.1 RefSeq gene 120560 121132 . - . ID=gene-NBT03_gp117;Dbxref=GeneID:72551533;Name=OPG138;gbkey=Gene;gene=OPG138;gene_biotype=protein_coding;locus_tag=NBT03_gp117;old_locus_tag=MPXV-M5312_HM12_Rivers-121 +NC_063383.1 RefSeq CDS 120560 121132 . - 0 ID=cds-YP_010377120.1;Parent=gene-NBT03_gp117;Dbxref=GenBank:YP_010377120.1,GeneID:72551533;Name=OPG138;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp123%3B Virion core and cleavage processing protein%3B similar to VACV-WR A13L and VACV-Cop A12L;gbkey=CDS;gene=OPG138;locus_tag=NBT03_gp117;product=A12 protein;protein_id=YP_010377120.1 +NC_063383.1 RefSeq gene 121156 121368 . - . ID=gene-NBT03_gp118;Dbxref=GeneID:72551534;Name=OPG139;gbkey=Gene;gene=OPG139;gene_biotype=protein_coding;locus_tag=NBT03_gp118;old_locus_tag=MPXV-M5312_HM12_Rivers-122 +NC_063383.1 RefSeq CDS 121156 121368 . - 0 ID=cds-YP_010377121.1;Parent=gene-NBT03_gp118;Dbxref=GenBank:YP_010377121.1,GeneID:72551534;Name=OPG139;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp124%3B IMV inner and outer membrane protein%3B virion maturation%3B similar to VACV-WR A14L and VACV-Cop A13L;gbkey=CDS;gene=OPG139;locus_tag=NBT03_gp118;product=IMV membrane protein A13L;protein_id=YP_010377121.1 +NC_063383.1 RefSeq gene 121474 121746 . - . ID=gene-NBT03_gp119;Dbxref=GeneID:72551535;Name=OPG140;gbkey=Gene;gene=OPG140;gene_biotype=protein_coding;locus_tag=NBT03_gp119;old_locus_tag=MPXV-M5312_HM12_Rivers-123 +NC_063383.1 RefSeq CDS 121474 121746 . - 0 ID=cds-YP_010377122.1;Parent=gene-NBT03_gp119;Dbxref=GenBank:YP_010377122.1,GeneID:72551535;Name=OPG140;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp125%3B IMV inner membrane protein%3B Essential IMV membrane protein%3B similar to VACV-WR A15L and VACV-Cop A14L;gbkey=CDS;gene=OPG140;locus_tag=NBT03_gp119;product=IMV membrane protein A14;protein_id=YP_010377122.1 +NC_063383.1 RefSeq gene 121763 121924 . - . ID=gene-NBT03_gp120;Dbxref=GeneID:72551536;Name=OPG141;gbkey=Gene;gene=OPG141;gene_biotype=protein_coding;locus_tag=NBT03_gp120;old_locus_tag=MPXV-M5312_HM12_Rivers-124 +NC_063383.1 RefSeq CDS 121763 121924 . - 0 ID=cds-YP_010377123.1;Parent=gene-NBT03_gp120;Dbxref=GenBank:YP_010377123.1,GeneID:72551536;Name=OPG141;Note=Taxonomic breadth: chordopoxvirinae%3B Non-essential IMV membrane protein%3B similar to VACV-WR A15.5L and VACV-Cop A14.5L;gbkey=CDS;gene=OPG141;locus_tag=NBT03_gp120;product=DUF1029 domain protein;protein_id=YP_010377123.1 +NC_063383.1 RefSeq gene 121914 122198 . - . ID=gene-NBT03_gp121;Dbxref=GeneID:72551537;Name=OPG142;gbkey=Gene;gene=OPG142;gene_biotype=protein_coding;locus_tag=NBT03_gp121;old_locus_tag=MPXV-M5312_HM12_Rivers-125 +NC_063383.1 RefSeq CDS 121914 122198 . - 0 ID=cds-YP_010377124.1;Parent=gene-NBT03_gp121;Dbxref=GenBank:YP_010377124.1,GeneID:72551537;Name=OPG142;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp126%3B Core protein%3B similar to VACV-WR A16L and VACV-Cop A15L;gbkey=CDS;gene=OPG142;locus_tag=NBT03_gp121;product=Core protein A15;protein_id=YP_010377124.1 +NC_063383.1 RefSeq gene 122182 123315 . - . ID=gene-NBT03_gp122;Dbxref=GeneID:72551538;Name=OPG143;gbkey=Gene;gene=OPG143;gene_biotype=protein_coding;locus_tag=NBT03_gp122;old_locus_tag=MPXV-M5312_HM12_Rivers-126 +NC_063383.1 RefSeq CDS 122182 123315 . - 0 ID=cds-YP_010377125.1;Parent=gene-NBT03_gp122;Dbxref=GenBank:YP_010377125.1,GeneID:72551538;Name=OPG143;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp127%3B soluble myristylated protein%3B essential for entry/fusion%3B similar to VACV-WR A17L and VACV-Cop A16L;gbkey=CDS;gene=OPG143;locus_tag=NBT03_gp122;product=Myristylated protein;protein_id=YP_010377125.1 +NC_063383.1 RefSeq gene 123318 123932 . - . ID=gene-NBT03_gp123;Dbxref=GeneID:72551539;Name=OPG144;gbkey=Gene;gene=OPG144;gene_biotype=protein_coding;locus_tag=NBT03_gp123;old_locus_tag=MPXV-M5312_HM12_Rivers-127 +NC_063383.1 RefSeq CDS 123318 123932 . - 0 ID=cds-YP_010377126.1;Parent=gene-NBT03_gp123;Dbxref=GenBank:YP_010377126.1,GeneID:72551539;Name=OPG144;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp128%3B IMV surface membrane protein%3B early function in virion morphgenesis%3B similar to VACV-WR A18L and VACV-Cop A17L;gbkey=CDS;gene=OPG144;locus_tag=NBT03_gp123;product=IMV membrane protein P21;protein_id=YP_010377126.1 +NC_063383.1 RefSeq gene 123947 125425 . + . ID=gene-NBT03_gp124;Dbxref=GeneID:72551540;Name=OPG145;gbkey=Gene;gene=OPG145;gene_biotype=protein_coding;locus_tag=NBT03_gp124;old_locus_tag=MPXV-M5312_HM12_Rivers-128 +NC_063383.1 RefSeq CDS 123947 125425 . + 0 ID=cds-YP_010377127.1;Parent=gene-NBT03_gp124;Dbxref=GenBank:YP_010377127.1,GeneID:72551540;Name=OPG145;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp129%3B virion core associated DNA helicase%3B post-replicative negative transcription elongation factor%3B transcript release factor%3B similar to VACV-WR A19R and VACV-Cop A18R;gbkey=CDS;gene=OPG145;locus_tag=NBT03_gp124;product=DNA helicase;protein_id=YP_010377127.1 +NC_063383.1 RefSeq gene 125406 125639 . - . ID=gene-NBT03_gp125;Dbxref=GeneID:72551541;Name=OPG146;gbkey=Gene;gene=OPG146;gene_biotype=protein_coding;locus_tag=NBT03_gp125;old_locus_tag=MPXV-M5312_HM12_Rivers-129 +NC_063383.1 RefSeq CDS 125406 125639 . - 0 ID=cds-YP_010377128.1;Parent=gene-NBT03_gp125;Dbxref=GenBank:YP_010377128.1,GeneID:72551541;Name=OPG146;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp130%3B Zinc finger-like protein%3B similar to VACV-WR A20L and VACV-Cop A19L;gbkey=CDS;gene=OPG146;locus_tag=NBT03_gp125;product=Zinc finger-like protein (1);protein_id=YP_010377128.1 +NC_063383.1 RefSeq gene 125640 125987 . - . ID=gene-NBT03_gp126;Dbxref=GeneID:72551542;Name=OPG147;gbkey=Gene;gene=OPG147;gene_biotype=protein_coding;locus_tag=NBT03_gp126;old_locus_tag=MPXV-M5312_HM12_Rivers-130 +NC_063383.1 RefSeq CDS 125640 125987 . - 0 ID=cds-YP_010377129.1;Parent=gene-NBT03_gp126;Dbxref=GenBank:YP_010377129.1,GeneID:72551542;Name=OPG147;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp131%3B IMV membrane protein%2C entry/fusion complex component%3B similar to VACV-WR A21L and VACV-Cop A21L;gbkey=CDS;gene=OPG147;locus_tag=NBT03_gp126;product=IMV membrane protein A21;protein_id=YP_010377129.1 +NC_063383.1 RefSeq gene 125986 127266 . + . ID=gene-NBT03_gp127;Dbxref=GeneID:72551543;Name=OPG148;gbkey=Gene;gene=OPG148;gene_biotype=protein_coding;locus_tag=NBT03_gp127;old_locus_tag=MPXV-M5312_HM12_Rivers-131 +NC_063383.1 RefSeq CDS 125986 127266 . + 0 ID=cds-YP_010377130.1;Parent=gene-NBT03_gp127;Dbxref=GenBank:YP_010377130.1,GeneID:72551543;Name=OPG148;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp132%3B processivity factor for the viral DNA polymerase%2C VPF%3B similar to VACV-WR A22R and VACV-Cop A20R;gbkey=CDS;gene=OPG148;locus_tag=NBT03_gp127;product=DNA polymerase processivity factor;protein_id=YP_010377130.1 +NC_063383.1 RefSeq gene 127196 127759 . + . ID=gene-NBT03_gp128;Dbxref=GeneID:72551544;Name=OPG149;gbkey=Gene;gene=OPG149;gene_biotype=protein_coding;locus_tag=NBT03_gp128;old_locus_tag=MPXV-M5312_HM12_Rivers-132 +NC_063383.1 RefSeq CDS 127196 127759 . + 0 ID=cds-YP_010377131.1;Parent=gene-NBT03_gp128;Dbxref=GenBank:YP_010377131.1,GeneID:72551544;Name=OPG149;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp133%3B Holliday junction resolvase%3B similar to VACV-WR A23R and VACV-Cop A22R;gbkey=CDS;gene=OPG149;locus_tag=NBT03_gp128;product=Holliday junction resolvase;protein_id=YP_010377131.1 +NC_063383.1 RefSeq gene 127779 128927 . + . ID=gene-NBT03_gp129;Dbxref=GeneID:72551545;Name=OPG150;gbkey=Gene;gene=OPG150;gene_biotype=protein_coding;locus_tag=NBT03_gp129;old_locus_tag=MPXV-M5312_HM12_Rivers-133 +NC_063383.1 RefSeq CDS 127779 128927 . + 0 ID=cds-YP_010377132.1;Parent=gene-NBT03_gp129;Dbxref=GenBank:YP_010377132.1,GeneID:72551545;Name=OPG150;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp134%3B intermediate transcription factor%2C VITF-3%2C 45 kDa subunit%3B similar to VACV-WR A24R and VACV-Cop A23R;gbkey=CDS;gene=OPG150;locus_tag=NBT03_gp129;product=Intermediate transcription factor VITF-3 (2);protein_id=YP_010377132.1 +NC_063383.1 RefSeq gene 128924 132418 . + . ID=gene-NBT03_gp130;Dbxref=GeneID:72551546;Name=OPG151;gbkey=Gene;gene=OPG151;gene_biotype=protein_coding;locus_tag=NBT03_gp130;old_locus_tag=MPXV-M5312_HM12_Rivers-134 +NC_063383.1 RefSeq CDS 128924 132418 . + 0 ID=cds-YP_010377133.1;Parent=gene-NBT03_gp130;Dbxref=GenBank:YP_010377133.1,GeneID:72551546;Name=OPG151;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp135%3B RNA polymerase%2C 132 kDa subunit (RPO132)%3B similar to VACV-WR A25R and VACV-Cop A24R;gbkey=CDS;gene=OPG151;locus_tag=NBT03_gp130;product=DNA-dependent RNA polymerase subunit rpo132;protein_id=YP_010377133.1 +NC_063383.1 RefSeq sequence_feature 132396 136092 . - . ID=id-NC_063383.1:132396..136092;exon_number=OPG152;gbkey=misc_feature;number=OPG152 +NC_063383.1 RefSeq gene 136138 137667 . - . ID=gene-NBT03_gp131;Dbxref=GeneID:72551547;Name=OPG153;gbkey=Gene;gene=OPG153;gene_biotype=protein_coding;locus_tag=NBT03_gp131;old_locus_tag=MPXV-M5312_HM12_Rivers-137 +NC_063383.1 RefSeq CDS 136138 137667 . - 0 ID=cds-YP_010377134.1;Parent=gene-NBT03_gp131;Dbxref=GenBank:YP_010377134.1,GeneID:72551547;Name=OPG153;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp138%3B major component of IMV surface tubules%3B A-type inclusion protein%3B P4c precursor%3B similar to VACV-WR A28L and VACV-Cop A26L;gbkey=CDS;gene=OPG153;locus_tag=NBT03_gp131;product=Orthopoxvirus A26L/A30L protein;protein_id=YP_010377134.1 +NC_063383.1 RefSeq gene 137718 138050 . - . ID=gene-NBT03_gp132;Dbxref=GeneID:72551548;Name=OPG154;gbkey=Gene;gene=OPG154;gene_biotype=protein_coding;locus_tag=NBT03_gp132;old_locus_tag=MPXV-M5312_HM12_Rivers-138 +NC_063383.1 RefSeq CDS 137718 138050 . - 0 ID=cds-YP_010377135.1;Parent=gene-NBT03_gp132;Dbxref=GenBank:YP_010377135.1,GeneID:72551548;Name=OPG154;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp139%3B IMV surface membrane 14 kDa fusion protein%3B binding to cell surface heparan%3B similar to VACV-WR A29L and VACV-Cop A27L;gbkey=CDS;gene=OPG154;locus_tag=NBT03_gp132;product=IMV surface fusion protein;protein_id=YP_010377135.1 +NC_063383.1 RefSeq gene 138051 138491 . - . ID=gene-NBT03_gp133;Dbxref=GeneID:72551549;Name=OPG155;gbkey=Gene;gene=OPG155;gene_biotype=protein_coding;locus_tag=NBT03_gp133;old_locus_tag=MPXV-M5312_HM12_Rivers-139 +NC_063383.1 RefSeq CDS 138051 138491 . - 0 ID=cds-YP_010377136.1;Parent=gene-NBT03_gp133;Dbxref=GenBank:YP_010377136.1,GeneID:72551549;Name=OPG155;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp140%3B IMV MP/Virus entry%3B similar to VACV-WR A30L and VACV-Cop A28L;gbkey=CDS;gene=OPG155;locus_tag=NBT03_gp133;product=Envelope protein A28 homolog;protein_id=YP_010377136.1 +NC_063383.1 RefSeq gene 138492 139409 . - . ID=gene-NBT03_gp134;Dbxref=GeneID:72551550;Name=OPG156;gbkey=Gene;gene=OPG156;gene_biotype=protein_coding;locus_tag=NBT03_gp134;old_locus_tag=MPXV-M5312_HM12_Rivers-140 +NC_063383.1 RefSeq CDS 138492 139409 . - 0 ID=cds-YP_010377137.1;Parent=gene-NBT03_gp134;Dbxref=GenBank:YP_010377137.1,GeneID:72551550;Name=OPG156;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp141%3B RNA polymerase%2C 35 kDa subunit (RPO35)%3B similar to VACV-WR A31L and VACV-Cop A29L;gbkey=CDS;gene=OPG156;locus_tag=NBT03_gp134;product=DNA-directed RNA polymerase 35 kDa subunit;protein_id=YP_010377137.1 +NC_063383.1 RefSeq gene 139372 139608 . - . ID=gene-NBT03_gp135;Dbxref=GeneID:72551551;Name=OPG157;gbkey=Gene;gene=OPG157;gene_biotype=protein_coding;locus_tag=NBT03_gp135;old_locus_tag=MPXV-M5312_HM12_Rivers-141 +NC_063383.1 RefSeq CDS 139372 139608 . - 0 ID=cds-YP_010377138.1;Parent=gene-NBT03_gp135;Dbxref=GenBank:YP_010377138.1,GeneID:72551551;Name=OPG157;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp142%3B IMV protein%3B similar to VACV-WR A32L and VACV-Cop A30L;gbkey=CDS;gene=OPG157;locus_tag=NBT03_gp135;product=IMV membrane protein A30;protein_id=YP_010377138.1 +NC_063383.1 RefSeq gene 139641 139769 . - . ID=gene-NBT03_gp136;Dbxref=GeneID:72551552;Name=OPG158;gbkey=Gene;gene=OPG158;gene_biotype=protein_coding;locus_tag=NBT03_gp136;old_locus_tag=MPXV-M5312_HM12_Rivers-142 +NC_063383.1 RefSeq CDS 139641 139769 . - 0 ID=cds-YP_010377139.1;Parent=gene-NBT03_gp136;Dbxref=GenBank:YP_010377139.1,GeneID:72551552;Name=OPG158;Note=Viral membrane assembly proteins (VMAP)%3B similar to VACV-Cop A30.5L;gbkey=CDS;gene=OPG158;locus_tag=NBT03_gp136;product=A32.5L;protein_id=YP_010377139.1 +NC_063383.1 RefSeq gene 139768 140205 . + . ID=gene-NBT03_gp137;Dbxref=GeneID:72551553;Name=OPG159;gbkey=Gene;gene=OPG159;gene_biotype=protein_coding;locus_tag=NBT03_gp137;old_locus_tag=MPXV-M5312_HM12_Rivers-143 +NC_063383.1 RefSeq CDS 139768 140205 . + 0 ID=cds-YP_010377140.1;Parent=gene-NBT03_gp137;Dbxref=GenBank:YP_010377140.1,GeneID:72551553;Name=OPG159;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp143%3B Hypothetical protein%3B similar to VACV-WR A33R and VACV-Cop A31R;gbkey=CDS;gene=OPG159;locus_tag=NBT03_gp137;product=CPXV166 protein;protein_id=YP_010377140.1 +NC_063383.1 RefSeq gene 140172 141074 . - . ID=gene-NBT03_gp138;Dbxref=GeneID:72551554;Name=OPG160;gbkey=Gene;gene=OPG160;gene_biotype=protein_coding;locus_tag=NBT03_gp138;old_locus_tag=MPXV-M5312_HM12_Rivers-144 +NC_063383.1 RefSeq CDS 140172 141074 . - 0 ID=cds-YP_010377141.1;Parent=gene-NBT03_gp138;Dbxref=GenBank:YP_010377141.1,GeneID:72551554;Name=OPG160;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp144%3B DNA packaging into virion%3B NTP-binding motif A%3B ATPase/DNA packaging protein%3B similar to VACV-WR A34L and VACV-Cop A32L;gbkey=CDS;gene=OPG160;locus_tag=NBT03_gp138;product=ATPase A32;protein_id=YP_010377141.1 +NC_063383.1 RefSeq gene 141102 141647 . + . ID=gene-NBT03_gp139;Dbxref=GeneID:72551555;Name=OPG161;gbkey=Gene;gene=OPG161;gene_biotype=protein_coding;locus_tag=NBT03_gp139;old_locus_tag=MPXV-M5312_HM12_Rivers-145 +NC_063383.1 RefSeq CDS 141102 141647 . + 0 ID=cds-YP_010377142.1;Parent=gene-NBT03_gp139;Dbxref=GenBank:YP_010377142.1,GeneID:72551555;Name=OPG161;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp145%3B EEV envelope glycoprotein%2C needed for formation of actin-containing microvilli and cell-to-cell spread of virion%3B interacts with VAC A36R%3B EEV membrane phosphoglycoprotein%2C C-type lectin-like domain%3B similar to VACV-WR A35R and VACV-Cop A33R;gbkey=CDS;gene=OPG161;locus_tag=NBT03_gp139;product=EEV glycoprotein (1);protein_id=YP_010377142.1 +NC_063383.1 RefSeq gene 141652 142158 . + . ID=gene-NBT03_gp140;Dbxref=GeneID:72551556;Name=OPG162;gbkey=Gene;gene=OPG162;gene_biotype=protein_coding;locus_tag=NBT03_gp140;old_locus_tag=MPXV-M5312_HM12_Rivers-146 +NC_063383.1 RefSeq CDS 141652 142158 . + 0 ID=cds-YP_010377143.1;Parent=gene-NBT03_gp140;Dbxref=GenBank:YP_010377143.1,GeneID:72551556;Name=OPG162;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp146%3B EEV envelope glycoprotein%2C lectin-like%3B required for infectivity of EEV%2C formation of actin-containing microvilli%2C and cell-to-cell spread of virion%3B C-type lectin-like IEV/EEV glycoprotein%3B similar to VACV-WR A36R and VACV-Cop A34R;gbkey=CDS;gene=OPG162;locus_tag=NBT03_gp140;product=EEV glycoprotein (2);protein_id=YP_010377143.1 +NC_063383.1 RefSeq gene 142202 142732 . + . ID=gene-NBT03_gp141;Dbxref=GeneID:72551557;Name=OPG163;gbkey=Gene;gene=OPG163;gene_biotype=protein_coding;locus_tag=NBT03_gp141;old_locus_tag=MPXV-M5312_HM12_Rivers-147 +NC_063383.1 RefSeq CDS 142202 142732 . + 0 ID=cds-YP_010377144.1;Parent=gene-NBT03_gp141;Dbxref=GenBank:YP_010377144.1,GeneID:72551557;Name=OPG163;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp147%3B MHC class II antigen presentation inhibitor%3B similar to VACV-WR A37R and VACV-Cop A35R;gbkey=CDS;gene=OPG163;locus_tag=NBT03_gp141;product=MHC class II antigen presentation inhibitor;protein_id=YP_010377144.1 +NC_063383.1 RefSeq gene 142778 143464 . + . ID=gene-NBT03_gp142;Dbxref=GeneID:72551558;Name=OPG164;gbkey=Gene;gene=OPG164;gene_biotype=protein_coding;locus_tag=NBT03_gp142;old_locus_tag=MPXV-M5312_HM12_Rivers-148 +NC_063383.1 RefSeq CDS 142778 143464 . + 0 ID=cds-YP_010377145.1;Parent=gene-NBT03_gp142;Dbxref=GenBank:YP_010377145.1,GeneID:72551558;Name=OPG164;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp148%3B IEV but not CEV envelope protein%3B plays critical role for actin tail formation%3B interacts with VAC A33R and A34R%3B IEV transmembrane phosphoprotein%3B similar to VACV-WR A38R and VACV-Cop A36R;gbkey=CDS;gene=OPG164;locus_tag=NBT03_gp142;product=IEV transmembrane phosphoprotein;protein_id=YP_010377145.1 +NC_063383.1 RefSeq gene 143516 144322 . + . ID=gene-NBT03_gp143;Dbxref=GeneID:72551559;Name=OPG165;gbkey=Gene;gene=OPG165;gene_biotype=protein_coding;locus_tag=NBT03_gp143;old_locus_tag=MPXV-M5312_HM12_Rivers-149 +NC_063383.1 RefSeq CDS 143516 144322 . + 0 ID=cds-YP_010377146.1;Parent=gene-NBT03_gp143;Dbxref=GenBank:YP_010377146.1,GeneID:72551559;Name=OPG165;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp149%3B Hypothetical protein%3B similar to VACV-WR A39R and VACV-Cop A37R;gbkey=CDS;gene=OPG165;locus_tag=NBT03_gp143;product=CPXV173 protein;protein_id=YP_010377146.1 +NC_063383.1 RefSeq gene 144398 144577 . + . ID=gene-NBT03_gp144;Dbxref=GeneID:72551560;Name=OPG166;gbkey=Gene;gene=OPG166;gene_biotype=protein_coding;locus_tag=NBT03_gp144 +NC_063383.1 RefSeq CDS 144398 144577 . + 0 ID=cds-YP_010415322.1;Parent=gene-NBT03_gp144;Dbxref=GenBank:YP_010415322.1,GeneID:72551560;Name=OPG166;Note=Hypothetical protein%3B according to YP_233043.1%2C this VACV-WR protein was purified by sucrose gradient centrifugation%3B similar to VACWR161 and VARGAR-A43R;gbkey=CDS;gene=OPG166;locus_tag=NBT03_gp144;product=hypothetical protein;protein_id=YP_010415322.1 +NC_063383.1 RefSeq gene 144574 145407 . - . ID=gene-NBT03_gp145;Dbxref=GeneID:72551561;Name=OPG167;gbkey=Gene;gene=OPG167;gene_biotype=protein_coding;locus_tag=NBT03_gp145;old_locus_tag=MPXV-M5312_HM12_Rivers-150 +NC_063383.1 RefSeq CDS 144574 145407 . - 0 ID=cds-YP_010377147.1;Parent=gene-NBT03_gp145;Dbxref=GenBank:YP_010377147.1,GeneID:72551561;Name=OPG167;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp150%3B integral membrane glycoprotein%3B immunoglobulin-like%3B regulation of the influx of extracellular Ca2+%3B CD47-like%3B similar to VACV-WR A40L and VACV-Cop A38L;gbkey=CDS;gene=OPG167;locus_tag=NBT03_gp145;product=CD47-like protein;protein_id=YP_010377147.1 +NC_063383.1 RefSeq sequence_feature 145423 145856 . + . ID=id-NC_063383.1:145423..145856;exon_number=OPG168;gbkey=misc_feature;number=OPG168 +NC_063383.1 RefSeq sequence_feature 145857 146039 . + . ID=id-NC_063383.1:145857..146039;exon_number=OPG169;gbkey=misc_feature;number=OPG169 +NC_063383.1 RefSeq gene 146113 146778 . - . ID=gene-NBT03_gp146;Dbxref=GeneID:72551562;Name=OPG170;gbkey=Gene;gene=OPG170;gene_biotype=protein_coding;locus_tag=NBT03_gp146;old_locus_tag=MPXV-M5312_HM12_Rivers-151 +NC_063383.1 RefSeq CDS 146113 146778 . - 0 ID=cds-YP_010377148.1;Parent=gene-NBT03_gp146;Dbxref=GenBank:YP_010377148.1,GeneID:72551562;Name=OPG170;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp151%3B secreted protein reducing infiltration of inflammatory cells into the infected area%3B Chemokine binding protein%3B similar to VACV-WR A41L and VACV-Cop A41L;gbkey=CDS;gene=OPG170;locus_tag=NBT03_gp146;product=Chemokine binding protein;protein_id=YP_010377148.1 +NC_063383.1 RefSeq gene 146988 147389 . + . ID=gene-NBT03_gp147;Dbxref=GeneID:72551563;Name=OPG171;gbkey=Gene;gene=OPG171;gene_biotype=protein_coding;locus_tag=NBT03_gp147;old_locus_tag=MPXV-M5312_HM12_Rivers-152 +NC_063383.1 RefSeq CDS 146988 147389 . + 0 ID=cds-YP_010377149.1;Parent=gene-NBT03_gp147;Dbxref=GenBank:YP_010377149.1,GeneID:72551563;Name=OPG171;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp152%3B Profilin-like protein%2C ATI-localized%3B similar to VACV-WR A42R and VACV-Cop A42R;gbkey=CDS;gene=OPG171;locus_tag=NBT03_gp147;product=Profilin domain protein;protein_id=YP_010377149.1 +NC_063383.1 RefSeq gene 147427 148017 . + . ID=gene-NBT03_gp148;Dbxref=GeneID:72551564;Name=OPG172;gbkey=Gene;gene=OPG172;gene_biotype=protein_coding;locus_tag=NBT03_gp148;old_locus_tag=MPXV-M5312_HM12_Rivers-153 +NC_063383.1 RefSeq CDS 147427 148017 . + 0 ID=cds-YP_010377150.1;Parent=gene-NBT03_gp148;Dbxref=GenBank:YP_010377150.1,GeneID:72551564;Name=OPG172;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp153%3B Type I membrane glycoprotein%3B similar to VACV-WR A43R and VACV-Cop A43R;gbkey=CDS;gene=OPG172;locus_tag=NBT03_gp148;product=Type-I membrane glycoprotein;protein_id=YP_010377150.1 +NC_063383.1 RefSeq gene 148037 148261 . + . ID=gene-NBT03_gp149;Dbxref=GeneID:72551565;Name=OPG173;gbkey=Gene;gene=OPG173;gene_biotype=protein_coding;locus_tag=NBT03_gp149;old_locus_tag=MPXV-M5312_HM12_Rivers-154 +NC_063383.1 RefSeq CDS 148037 148261 . + 0 ID=cds-YP_010377151.1;Parent=gene-NBT03_gp149;Dbxref=GenBank:YP_010377151.1,GeneID:72551565;Name=OPG173;Note=Old product: MPXVgp154%3B Hypothetical protein%3B similar to VACV-WR A44R and VACV-Cop A43.5R;gbkey=CDS;gene=OPG173;locus_tag=NBT03_gp149;product=MPXVgp154;protein_id=YP_010377151.1 +NC_063383.1 RefSeq gene 148355 149395 . - . ID=gene-NBT03_gp150;Dbxref=GeneID:72551566;Name=OPG174;gbkey=Gene;gene=OPG174;gene_biotype=protein_coding;locus_tag=NBT03_gp150;old_locus_tag=MPXV-M5312_HM12_Rivers-155 +NC_063383.1 RefSeq CDS 148355 149395 . - 0 ID=cds-YP_010377152.1;Parent=gene-NBT03_gp150;Dbxref=GenBank:YP_010377152.1,GeneID:72551566;Name=OPG174;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp155%3B 3-b-Hydroxy-delta5-steroid dehydrogenase%3B 3 beta-hydroxysteroid dehydrogenase/delta 5->4 isomerase%3B similar to VACV-WR A45L and VACV-Cop A44L;gbkey=CDS;gene=OPG174;locus_tag=NBT03_gp150;product=Hydroxysteroid dehydrogenase;protein_id=YP_010377152.1 +NC_063383.1 RefSeq gene 149442 149819 . + . ID=gene-NBT03_gp151;Dbxref=GeneID:72551567;Name=OPG175;gbkey=Gene;gene=OPG175;gene_biotype=protein_coding;locus_tag=NBT03_gp151;old_locus_tag=MPXV-M5312_HM12_Rivers-156 +NC_063383.1 RefSeq CDS 149442 149819 . + 0 ID=cds-YP_010377153.1;Parent=gene-NBT03_gp151;Dbxref=GenBank:YP_010377153.1,GeneID:72551567;Name=OPG175;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp156%3B virion core protein%3B Inactive Cu-Zn superoxide dismutase-like virion protein%3B similar to VACV-WR A46R and VACV-Cop A45R;gbkey=CDS;gene=OPG175;locus_tag=NBT03_gp151;product=Copper/zinc superoxide dismutase;protein_id=YP_010377153.1 +NC_063383.1 RefSeq gene 149809 150531 . + . ID=gene-NBT03_gp152;Dbxref=GeneID:72551568;Name=OPG176;gbkey=Gene;gene=OPG176;gene_biotype=protein_coding;locus_tag=NBT03_gp152;old_locus_tag=MPXV-M5312_HM12_Rivers-157 +NC_063383.1 RefSeq CDS 149809 150531 . + 0 ID=cds-YP_010377154.1;Parent=gene-NBT03_gp152;Dbxref=GenBank:YP_010377154.1,GeneID:72551568;Name=OPG176;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp157%3B IL-1/TLR signaling inhibitor%3B similar to VACV-WR A47R and VACV-Cop A46R;gbkey=CDS;gene=OPG176;locus_tag=NBT03_gp152;product=Bcl-2-like protein;protein_id=YP_010377154.1 +NC_063383.1 RefSeq sequence_feature 150684 151407 . - . ID=id-NC_063383.1:150684..151407;exon_number=OPG177;gbkey=misc_feature;number=OPG177 +NC_063383.1 RefSeq gene 151509 152123 . + . ID=gene-NBT03_gp153;Dbxref=GeneID:72551569;Name=OPG178;gbkey=Gene;gene=OPG178;gene_biotype=protein_coding;locus_tag=NBT03_gp153;old_locus_tag=MPXV-M5312_HM12_Rivers-158 +NC_063383.1 RefSeq CDS 151509 152123 . + 0 ID=cds-YP_010377155.1;Parent=gene-NBT03_gp153;Dbxref=GenBank:YP_010377155.1,GeneID:72551569;Name=OPG178;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp159%3B thymidylate kinase%3B start of ORF is missing approx. 37 AA compared to CPXVs%3B similar to VACV-WR A49R and VACV-Cop A48R;gbkey=CDS;gene=OPG178;locus_tag=NBT03_gp153;product=Thymidylate kinase;protein_id=YP_010377155.1 +NC_063383.1 RefSeq sequence_feature 152172 152660 . + . ID=id-NC_063383.1:152172..152660;exon_number=OPG179;gbkey=misc_feature;number=OPG179 +NC_063383.1 RefSeq gene 152692 154371 . + . ID=gene-NBT03_gp154;Dbxref=GeneID:72551570;Name=OPG180;gbkey=Gene;gene=OPG180;gene_biotype=protein_coding;locus_tag=NBT03_gp154;old_locus_tag=MPXV-M5312_HM12_Rivers-159 +NC_063383.1 RefSeq CDS 152692 154371 . + 0 ID=cds-YP_010377156.1;Parent=gene-NBT03_gp154;Dbxref=GenBank:YP_010377156.1,GeneID:72551570;Name=OPG180;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp160%3B ATP-dependent DNA ligase%3B similar to VACV-WR A50R and VACV-Cop A50R;gbkey=CDS;gene=OPG180;locus_tag=NBT03_gp154;product=DNA ligase (2);protein_id=YP_010377156.1 +NC_063383.1 RefSeq gene 154412 155416 . + . ID=gene-NBT03_gp155;Dbxref=GeneID:72551571;Name=OPG181;gbkey=Gene;gene=OPG181;gene_biotype=protein_coding;locus_tag=NBT03_gp155;old_locus_tag=MPXV-M5312_HM12_Rivers-160 +NC_063383.1 RefSeq CDS 154412 155416 . + 0 ID=cds-YP_010377157.1;Parent=gene-NBT03_gp155;Dbxref=GenBank:YP_010377157.1,GeneID:72551571;Name=OPG181;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp161%3B Hypothetical protein%3B similar to VACV-WR A51R and VACV-Cop A51R;gbkey=CDS;gene=OPG181;locus_tag=NBT03_gp155;product=M137R;protein_id=YP_010377157.1 +NC_063383.1 RefSeq sequence_feature 155485 156037 . + . ID=id-NC_063383.1:155485..156037;exon_number=OPG182;gbkey=misc_feature;number=OPG182 +NC_063383.1 RefSeq sequence_feature 156355 156916 . + . ID=id-NC_063383.1:156355..156916;exon_number=OPG183;gbkey=misc_feature;number=OPG183 +NC_063383.1 RefSeq sequence_feature 157176 158867 . + . ID=id-NC_063383.1:157176..158867;exon_number=OPG184;gbkey=misc_feature;number=OPG184 +NC_063383.1 RefSeq gene 158917 159858 . + . ID=gene-NBT03_gp156;Dbxref=GeneID:72551572;Name=OPG185;gbkey=Gene;gene=OPG185;gene_biotype=protein_coding;locus_tag=NBT03_gp156;old_locus_tag=MPXV-M5312_HM12_Rivers-162 +NC_063383.1 RefSeq CDS 158917 159858 . + 0 ID=cds-YP_010377158.1;Parent=gene-NBT03_gp156;Dbxref=GenBank:YP_010377158.1,GeneID:72551572;Name=OPG185;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp163%3B EEV envelope and cell membrane glycoprotein hemagglutinin%3B inhibition of the ability of infected cells to fuse%3B interacts with VAC F13L%3B similar to VACV-WR B2R and VACV-Cop A56R;gbkey=CDS;gene=OPG185;locus_tag=NBT03_gp156;product=Hemagglutinin;protein_id=YP_010377158.1 +NC_063383.1 RefSeq sequence_feature 159876 160470 . + . ID=id-NC_063383.1:159876..160470;exon_number=OPG186;gbkey=misc_feature;number=OPG186 +NC_063383.1 RefSeq gene 160622 161533 . + . ID=gene-NBT03_gp157;Dbxref=GeneID:72551573;Name=OPG187;gbkey=Gene;gene=OPG187;gene_biotype=protein_coding;locus_tag=NBT03_gp157;old_locus_tag=MPXV-M5312_HM12_Rivers-163 +NC_063383.1 RefSeq CDS 160622 161533 . + 0 ID=cds-YP_010377159.1;Parent=gene-NBT03_gp157;Dbxref=GenBank:YP_010377159.1,GeneID:72551573;Name=OPG187;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp164%3B serine%3B Ser/Thr Kinase%3B similar to VACV-WR B3R and VACV-Cop B1R;gbkey=CDS;gene=OPG187;locus_tag=NBT03_gp157;product=Ser/thr kinase;protein_id=YP_010377159.1 +NC_063383.1 RefSeq gene 161596 163107 . + . ID=gene-NBT03_gp158;Dbxref=GeneID:72551574;Name=OPG188;gbkey=Gene;gene=OPG188;gene_biotype=protein_coding;locus_tag=NBT03_gp158;old_locus_tag=MPXV-M5312_HM12_Rivers-164 +NC_063383.1 RefSeq CDS 161596 163107 . + 0 ID=cds-YP_010377160.1;Parent=gene-NBT03_gp158;Dbxref=GenBank:YP_010377160.1,GeneID:72551574;Name=OPG188;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp165%3B schlafen-like%3B similar to VACV-WR B4R and VACV-Cop B2R;gbkey=CDS;gene=OPG188;locus_tag=NBT03_gp158;product=Schlafen (1);protein_id=YP_010377160.1 +NC_063383.1 RefSeq gene 163333 165018 . + . ID=gene-NBT03_gp159;Dbxref=GeneID:72551575;Name=OPG189;gbkey=Gene;gene=OPG189;gene_biotype=protein_coding;locus_tag=NBT03_gp159;old_locus_tag=MPXV-M5312_HM12_Rivers-165 +NC_063383.1 RefSeq CDS 163333 165018 . + 0 ID=cds-YP_010377161.1;Parent=gene-NBT03_gp159;Dbxref=GenBank:YP_010377161.1,GeneID:72551575;Name=OPG189;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp166%3B ankyrin-like%3B similar to VACV-WR B5R and VACV-Cop B4R;gbkey=CDS;gene=OPG189;locus_tag=NBT03_gp159;product=Ankyrin repeat protein (25);protein_id=YP_010377161.1 +NC_063383.1 RefSeq gene 165122 166075 . + . ID=gene-NBT03_gp160;Dbxref=GeneID:72551576;Name=OPG190;gbkey=Gene;gene=OPG190;gene_biotype=protein_coding;locus_tag=NBT03_gp160;old_locus_tag=MPXV-M5312_HM12_Rivers-166 +NC_063383.1 RefSeq CDS 165122 166075 . + 0 ID=cds-YP_010377162.1;Parent=gene-NBT03_gp160;Dbxref=GenBank:YP_010377162.1,GeneID:72551576;Name=OPG190;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp167%3B palmitated 42 kDa glycoprotein located both on the membranes of infected cells and on EEV envelope%3B complement control protein-like%3B EEV type-1 membrane glycoprotein%2C protective antigen%3B similar to VACV-WR B6R and VACV-Cop B5R;gbkey=CDS;gene=OPG190;locus_tag=NBT03_gp160;product=EEV type-I membrane glycoprotein;protein_id=YP_010377162.1 +NC_063383.1 RefSeq gene 166161 166667 . + . ID=gene-NBT03_gp161;Dbxref=GeneID:72551577;Name=OPG191;gbkey=Gene;gene=OPG191;gene_biotype=protein_coding;locus_tag=NBT03_gp161;old_locus_tag=MPXV-M5312_HM12_Rivers-167 +NC_063383.1 RefSeq CDS 166161 166667 . + 0 ID=cds-YP_010377163.1;Parent=gene-NBT03_gp161;Dbxref=GenBank:YP_010377163.1,GeneID:72551577;Name=OPG191;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp168%3B Ankyrin-like protein%3B similar to VACV-WR B7R and VACV-Cop B6R;gbkey=CDS;gene=OPG191;locus_tag=NBT03_gp161;product=Ankyrin-like protein (46);protein_id=YP_010377163.1 +NC_063383.1 RefSeq gene 166731 167279 . + . ID=gene-NBT03_gp162;Dbxref=GeneID:72551578;Name=OPG192;gbkey=Gene;gene=OPG192;gene_biotype=protein_coding;locus_tag=NBT03_gp162;old_locus_tag=MPXV-M5312_HM12_Rivers-168 +NC_063383.1 RefSeq CDS 166731 167279 . + 0 ID=cds-YP_010377164.1;Parent=gene-NBT03_gp162;Dbxref=GenBank:YP_010377164.1,GeneID:72551578;Name=OPG192;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp169%3B Virulence%2C ER resident%3B similar to VACV-WR B8R and VACV-Cop B7R;gbkey=CDS;gene=OPG192;locus_tag=NBT03_gp162;product=Virulence protein;protein_id=YP_010377164.1 +NC_063383.1 RefSeq gene 167334 168137 . + . ID=gene-NBT03_gp163;Dbxref=GeneID:72551579;Name=OPG193;gbkey=Gene;gene=OPG193;gene_biotype=protein_coding;locus_tag=NBT03_gp163;old_locus_tag=MPXV-M5312_HM12_Rivers-169 +NC_063383.1 RefSeq CDS 167334 168137 . + 0 ID=cds-YP_010377165.1;Parent=gene-NBT03_gp163;Dbxref=GenBank:YP_010377165.1,GeneID:72551579;Name=OPG193;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp170%3B secreted IFN-g binding protein%3B Soluble IFN-g receptor-like protein%3B similar to VACV-WR B9R and VACV-Cop B8R;gbkey=CDS;gene=OPG193;locus_tag=NBT03_gp163;product=Soluble interferon-gamma receptor-like protein;protein_id=YP_010377165.1 +NC_063383.1 RefSeq gene 168230 168895 . + . ID=gene-NBT03_gp164;Dbxref=GeneID:72551580;Name=OPG195;gbkey=Gene;gene=OPG195;gene_biotype=protein_coding;locus_tag=NBT03_gp164;old_locus_tag=MPXV-M5312_HM12_Rivers-170 +NC_063383.1 RefSeq CDS 168230 168895 . + 0 ID=cds-YP_010377166.1;Parent=gene-NBT03_gp164;Dbxref=GenBank:YP_010377166.1,GeneID:72551580;Name=OPG195;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp171%3B shope fibroma virus T4 protein-like%3B ER-localized apoptosis regulator%3B similar to VACV-WR B10R and VACV-Cop B9R;gbkey=CDS;gene=OPG195;locus_tag=NBT03_gp164;product=Intracellular viral protein;protein_id=YP_010377166.1 +NC_063383.1 RefSeq sequence_feature 169001 169642 . + . ID=id-NC_063383.1:169001..169642;exon_number=OPG196;gbkey=misc_feature;number=OPG196 +NC_063383.1 RefSeq gene 169670 169972 . + . ID=gene-NBT03_gp165;Dbxref=GeneID:72551581;Name=OPG197;gbkey=Gene;gene=OPG197;gene_biotype=protein_coding;locus_tag=NBT03_gp165;old_locus_tag=MPXV-M5312_HM12_Rivers-171 +NC_063383.1 RefSeq CDS 169670 169972 . + 0 ID=cds-YP_010377167.1;Parent=gene-NBT03_gp165;Dbxref=GenBank:YP_010377167.1,GeneID:72551581;Name=OPG197;Note=Taxonomic breadth: chordopoxvirinae%3B Hypothetical protein%3B similar to VACV-Cop-B11R;gbkey=CDS;gene=OPG197;locus_tag=NBT03_gp165;product=CPXV205 protein;protein_id=YP_010377167.1 +NC_063383.1 RefSeq gene 170038 170886 . + . ID=gene-NBT03_gp166;Dbxref=GeneID:72551582;Name=OPG198;gbkey=Gene;gene=OPG198;gene_biotype=protein_coding;locus_tag=NBT03_gp166;old_locus_tag=MPXV-M5312_HM12_Rivers-172 +NC_063383.1 RefSeq CDS 170038 170886 . + 0 ID=cds-YP_010377168.1;Parent=gene-NBT03_gp166;Dbxref=GenBank:YP_010377168.1,GeneID:72551582;Name=OPG198;Note=Taxonomic breadth: poxviridae%3B protein kinase-like%3B similar to VACV-WR B11R and VACV-Cop B12R;gbkey=CDS;gene=OPG198;locus_tag=NBT03_gp166;product=Ser/thr kinase;protein_id=YP_010377168.1 +NC_063383.1 RefSeq gene 170988 172022 . + . ID=gene-NBT03_gp167;Dbxref=GeneID:72551583;Name=OPG199;gbkey=Gene;gene=OPG199;gene_biotype=protein_coding;locus_tag=NBT03_gp167;old_locus_tag=MPXV-M5312_HM12_Rivers-173 +NC_063383.1 RefSeq CDS 170988 172022 . + 0 ID=cds-YP_010377169.1;Parent=gene-NBT03_gp167;Dbxref=GenBank:YP_010377169.1,GeneID:72551583;Name=OPG199;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp173%3B serine protease inhibitor-like%2C SPI-2%3B inhibition of the IL-1b converting enzyme%3B apoptosis inhibition%3B Serpin 1%2C2%2C3%3B similar to VACV-WR B12R and VACV-Cop K2L;gbkey=CDS;gene=OPG199;locus_tag=NBT03_gp167;product=Serpin;protein_id=YP_010377169.1 +NC_063383.1 RefSeq gene 172150 172599 . + . ID=gene-NBT03_gp168;Dbxref=GeneID:72551584;Name=OPG200;gbkey=Gene;gene=OPG200;gene_biotype=protein_coding;locus_tag=NBT03_gp168;old_locus_tag=MPXV-M5312_HM12_Rivers-174 +NC_063383.1 RefSeq CDS 172150 172599 . + 0 ID=cds-YP_010377170.1;Parent=gene-NBT03_gp168;Dbxref=GenBank:YP_010377170.1,GeneID:72551584;Name=OPG200;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp174%3B Hypothetical protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR B13R and VACV-Cop C16L and B15R;gbkey=CDS;gene=OPG200;locus_tag=NBT03_gp168;product=Bcl-2-like protein;protein_id=YP_010377170.1 +NC_063383.1 RefSeq sequence_feature 172685 173697 . + . ID=id-NC_063383.1:172685..173697;exon_number=OPG201;gbkey=misc_feature;number=OPG201 +NC_063383.1 RefSeq sequence_feature 173744 174187 . - . ID=id-NC_063383.1:173744..174187;exon_number=OPG202;gbkey=misc_feature;number=OPG202 +NC_063383.1 RefSeq sequence_feature 174328 174456 . + . ID=id-NC_063383.1:174328..174456;exon_number=OPG203;gbkey=misc_feature;number=OPG203 +NC_063383.1 RefSeq gene 174532 175587 . + . ID=gene-NBT03_gp169;Dbxref=GeneID:72551585;Name=OPG204;gbkey=Gene;gene=OPG204;gene_biotype=protein_coding;locus_tag=NBT03_gp169;old_locus_tag=MPXV-M5312_HM12_Rivers-177 +NC_063383.1 RefSeq CDS 174532 175587 . + 0 ID=cds-YP_010377172.1;Parent=gene-NBT03_gp169;Dbxref=GenBank:YP_010377172.1,GeneID:72551585;Name=OPG204;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp177%3B cell surface antigen and secreted IFN-a%3B IFN-alpha/beta receptor glycoprotein%3B similar to VACV-WR B16R and VACV-Cop B19R;gbkey=CDS;gene=OPG204;locus_tag=NBT03_gp169;product=IFN-alpha/beta-receptor-like secreted glycoprotein;protein_id=YP_010377172.1 +NC_063383.1 RefSeq gene 175656 178019 . + . ID=gene-NBT03_gp170;Dbxref=GeneID:72551586;Name=OPG205;gbkey=Gene;gene=OPG205;gene_biotype=protein_coding;locus_tag=NBT03_gp170;old_locus_tag=MPXV-M5312_HM12_Rivers-178 +NC_063383.1 RefSeq CDS 175656 178019 . + 0 ID=cds-YP_010377173.1;Parent=gene-NBT03_gp170;Dbxref=GenBank:YP_010377173.1,GeneID:72551586;Name=OPG205;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp178%3B ankyrin-like%3B similar to VACV-WR B17R and VACV-Cop B20R;gbkey=CDS;gene=OPG205;locus_tag=NBT03_gp170;product=Ankyrin repeat protein (44);protein_id=YP_010377173.1 +NC_063383.1 RefSeq sequence_feature 178118 178916 . + . ID=id-NC_063383.1:178118..178916;exon_number=OPG206;gbkey=misc_feature;number=OPG206 +NC_063383.1 RefSeq gene 179266 180339 . + . ID=gene-NBT03_gp171;Dbxref=GeneID:72551587;Name=OPG208;gbkey=Gene;gene=OPG208;gene_biotype=protein_coding;locus_tag=NBT03_gp171;old_locus_tag=MPXV-M5312_HM12_Rivers-180 +NC_063383.1 RefSeq CDS 179266 180339 . + 0 ID=cds-YP_010377174.1;Parent=gene-NBT03_gp171;Dbxref=GenBank:YP_010377174.1,GeneID:72551587;Name=OPG208;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp180%3B serine protease inhibitor-like%2C SPI-1%3B apoptosis inhibition%3B Serpin 1%2C2%2C3%3B Actual start may be at position 179%2C074%3B annotated start of ORF is missing approx. 17 AA compared to CPXVs%3B similar to VACV-WR B19R and VACV-Cop K2L;gbkey=CDS;gene=OPG208;locus_tag=NBT03_gp171;product=Serpin;protein_id=YP_010377174.1 +NC_063383.1 RefSeq gene 180518 181090 . + . ID=gene-NBT03_gp172;Dbxref=GeneID:72551588;Name=OPG209;gbkey=Gene;gene=OPG209;gene_biotype=protein_coding;locus_tag=NBT03_gp172;old_locus_tag=MPXV-M5312_HM12_Rivers-181 +NC_063383.1 RefSeq CDS 180518 181090 . + 0 ID=cds-YP_010377175.1;Parent=gene-NBT03_gp172;Dbxref=GenBank:YP_010377175.1,GeneID:72551588;Name=OPG209;Note=Old product: MPXVgp181%3B Hypothetical protein%3B similar to VACV-WR B20R and VACV-Cop C14L;gbkey=CDS;gene=OPG209;locus_tag=NBT03_gp172;product=Virulence protein;protein_id=YP_010377175.1 +NC_063383.1 RefSeq gene 181356 186998 . + . ID=gene-NBT03_gp173;Dbxref=GeneID:72551589;Name=OPG210;gbkey=Gene;gene=OPG210;gene_biotype=protein_coding;locus_tag=NBT03_gp173;old_locus_tag=MPXV-M5312_HM12_Rivers-182 +NC_063383.1 RefSeq CDS 181356 186998 . + 0 ID=cds-YP_010377176.1;Parent=gene-NBT03_gp173;Dbxref=GenBank:YP_010377176.1,GeneID:72551589;Name=OPG210;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp182%3B Surface glycoprotein%3B putative membrane-associated glycoprotein%3B cadherin-like domain%3B similar to VACV-WR B21R;gbkey=CDS;gene=OPG210;locus_tag=NBT03_gp173;product=B22R family protein;protein_id=YP_010377176.1 +NC_063383.1 RefSeq sequence_feature 187317 187743 . + . ID=id-NC_063383.1:187317..187743;exon_number=OPG212;gbkey=misc_feature;number=OPG212 +NC_063383.1 RefSeq sequence_feature 187822 188298 . + . ID=id-NC_063383.1:187822..188298;exon_number=OPG213;gbkey=misc_feature;number=OPG213 +NC_063383.1 RefSeq sequence_feature 188458 188963 . + . ID=id-NC_063383.1:188458..188963;exon_number=OPG214;gbkey=misc_feature;number=OPG214 +NC_063383.1 RefSeq gene 189199 189660 . + . ID=gene-NBT03_gp174;Dbxref=GeneID:72551590;Name=OPG005;gbkey=Gene;gene=OPG005;gene_biotype=protein_coding;locus_tag=NBT03_gp174;old_locus_tag=MPXV-M5312_HM12_Rivers-184 +NC_063383.1 RefSeq CDS 189199 189660 . + 0 ID=cds-YP_010377177.1;Parent=gene-NBT03_gp174;Dbxref=GenBank:YP_010377177.1,GeneID:72551590;Name=OPG005;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp185%3B VAC B15R-like%3B Hypothetical protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR N1R and VACV-Cop C16L and B22R;gbkey=CDS;gene=OPG005;locus_tag=NBT03_gp174;product=Bcl-2-like protein;protein_id=YP_010377177.1 +NC_063383.1 RefSeq gene 190410 190940 . + . ID=gene-NBT03_gp175;Dbxref=GeneID:72551591;Name=OPG016;gbkey=Gene;gene=OPG016;gene_biotype=protein_coding;locus_tag=NBT03_gp175;old_locus_tag=MPXV-M5312_HM12_Rivers-186 +NC_063383.1 RefSeq CDS 190410 190940 . + 0 ID=cds-YP_010377184.1;Parent=gene-NBT03_gp175;Dbxref=GenBank:YP_010377184.1,GeneID:72551591;Name=OPG016;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp187%3B similar to VACV-WR N3R;gbkey=CDS;gene=OPG016;locus_tag=NBT03_gp175;product=Brix domain protein;protein_id=YP_010377184.1 +NC_063383.1 RefSeq long_terminal_repeat 190788 197209 . + . ID=id-NC_063383.1:190788..197209;gbkey=repeat_region;rpt_type=long_terminal_repeat +NC_063383.1 RefSeq gene 191054 192367 . + . ID=gene-NBT03_gp176;Dbxref=GeneID:72551592;Name=OPG015_dup;gbkey=Gene;gene=OPG015_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp176;old_locus_tag=MPXV-M5312_HM12_Rivers-187 +NC_063383.1 RefSeq CDS 191054 192367 . + 0 ID=cds-YP_010377179.1;Parent=gene-NBT03_gp176;Dbxref=GenBank:YP_010377179.1,GeneID:72551592;Name=OPG015_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp188%3B ankyrin-like%3B Ankyrin (CPXV-017)%3B similar to VACV-WR N4R;gbkey=CDS;gene=OPG015_dup;locus_tag=NBT03_gp176;product=Ankyrin repeat protein (39);protein_id=YP_010377179.1 +NC_063383.1 RefSeq gene 192603 194369 . + . ID=gene-NBT03_gp177;Dbxref=GeneID:72551593;Name=OPG003_dup;gbkey=Gene;gene=OPG003_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp177;old_locus_tag=MPXV-M5312_HM12_Rivers-188 +NC_063383.1 RefSeq CDS 192603 194369 . + 0 ID=cds-YP_010377180.1;Parent=gene-NBT03_gp177;Dbxref=GenBank:YP_010377180.1,GeneID:72551593;Name=OPG003_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp189%3B ankyrin-like%3B similar to VACV-WR J1R and VACV-Cop C19L;gbkey=CDS;gene=OPG003_dup;locus_tag=NBT03_gp177;product=Ankyrin repeat protein (25);protein_id=YP_010377180.1 +NC_063383.1 RefSeq gene 194459 195508 . + . ID=gene-NBT03_gp178;Dbxref=GeneID:72551594;Name=OPG002_dup;gbkey=Gene;gene=OPG002_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp178;old_locus_tag=MPXV-M5312_HM12_Rivers-189 +NC_063383.1 RefSeq CDS 194459 195508 . + 0 ID=cds-YP_010377181.1;Parent=gene-NBT03_gp178;Dbxref=GenBank:YP_010377181.1,GeneID:72551594;Name=OPG002_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp190%3B secreted TNF binding protein%3B TNF receptor (CrmB)%3B similar to VACV-WR J2R and VACV-Cop C22L;gbkey=CDS;gene=OPG002_dup;locus_tag=NBT03_gp178;product=Crm-B secreted TNF-alpha-receptor-like protein;protein_id=YP_010377181.1 +NC_063383.1 RefSeq gene 195635 196375 . + . ID=gene-NBT03_gp179;Dbxref=GeneID:72551595;Name=OPG001_dup;gbkey=Gene;gene=OPG001_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp179;old_locus_tag=MPXV-M5312_HM12_Rivers-190 +NC_063383.1 RefSeq CDS 195635 196375 . + 0 ID=cds-YP_010377182.1;Parent=gene-NBT03_gp179;Dbxref=GenBank:YP_010377182.1,GeneID:72551595;Name=OPG001_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp191%3B Chemokine binding protein (Cop-C23L)%3B most abundant secreted protein%3B CC-chemokine binding protein%3B similar to VACV-WR J3R and VACV-Cop C23L and B29R;gbkey=CDS;gene=OPG001_dup;locus_tag=NBT03_gp179;product=Chemokine binding protein;protein_id=YP_010377182.1 diff --git a/data/nextstrain/mpx/hmpxv/NC_063383.1/pathogen.json b/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/pathogen.json similarity index 69% rename from data/nextstrain/mpx/hmpxv/NC_063383.1/pathogen.json rename to data_output/nextstrain/mpox/clade-iib/rivers/unreleased/pathogen.json index 5313196c..499016ea 100644 --- a/data/nextstrain/mpx/hmpxv/NC_063383.1/pathogen.json +++ b/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/pathogen.json @@ -7,10 +7,23 @@ "terminalBandwidth": 200, "windowSize": 30 }, + "attributes": { + "name": { + "value": "hMPXV", + "valueFriendly": "Human Monkeypox (hMPXV)" + }, + "reference": { + "value": "NC_063383.1", + "valueFriendly": "MPXV-M5312_HM12_Rivers" + } + }, "compatibility": { "cli": "3.0.0-alpha.0", "web": "3.0.0-alpha.0" }, + "deprecated": false, + "enabled": true, + "experimental": false, "files": { "changelog": "CHANGELOG.md", "examples": "sequences.fasta", @@ -20,6 +33,7 @@ "reference": "reference.fasta", "treeJson": "tree.json" }, + "official": true, "qc": { "frameShifts": { "enabled": true, @@ -79,34 +93,5 @@ "schemaVersion": "3.0.0", "version": { "tag": "unreleased" - }, - "attributes": { - "name": "Human Monkeypox (hMPXV)", - "reference name": "MPXV-M5312_HM12_Rivers", - "reference accession": "NC_063383.1" - }, - "maintenance": { - "website": [ - "https://nextstrain.org", - "https://clades.nextstrain.org" - ], - "documentation": [ - "https://github.com/nextstrain/nextclade_data", - "https://docs.nextstrain.org/projects/nextclade" - ], - "source code": [ - "https://github.com/nextstrain/nextclade_data", - "https://github.com/neherlab/nextclade_data_workflows" - ], - "issues": [ - "https://github.com/nextstrain/nextclade_data", - "https://github.com/nextstrain/nextclade_data/issues" - ], - "organizations": [ - "Nextstrain" - ], - "authors": [ - "Nextstrain team " - ] } } diff --git a/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/reference.fasta b/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/reference.fasta new file mode 100644 index 00000000..0f1d13ac --- /dev/null +++ b/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/reference.fasta @@ -0,0 +1,2 @@ +>NC_063383.1 Monkeypox virus, complete genome +ATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTAACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATTTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAAACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACAAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTTGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAAT diff --git a/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/sequences.fasta b/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/sequences.fasta new file mode 100644 index 00000000..1701fd6f --- /dev/null +++ b/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/sequences.fasta @@ -0,0 +1,10 @@ +>MPXV_USA_2022_MA001 | ON563414.2 +TATTATATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCRAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTTGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGAGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGAGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATATAATA +>Monkeypox/PT0001/2022|sampling_date_20220504_v2 +CGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGNAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACNTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTNAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACNGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCNTTTGAGAAGACAATAATATCCTNGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTANGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACNGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTNAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAANNGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTANGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCNNNTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTANCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTAACTAACTTATGANTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAANACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATANTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATNAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATNAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATNCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCNAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTNNAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATNAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCNTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATNAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTANTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCNTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCNNTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCNGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTNNTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTNGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCANTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTNAATACATCTATATTANGATTTGATGTTGTCGCGTANTNNTCTACAATATTAATACCANTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTNAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAANNNATTNATATTTTTATAGTCGACTGACGACAATAACAAAATNACNACATCNTTTTTGANNNNNNNNNNNTTTNNNNTAACGTATGCCTTTNNTGGANNNTCACCATCATACNCNNATAATGGATTTGCACCACTTTCTATTAATGATTNTNNACTACTGGCANCGATGTTAAATGNNTTACAACTATCATAGNGTATNNTATCGTTAACCATGATTGGTTGTTGATGTTATCACANNTTTTTGGTNNNTTTCATTTCAGNTANNTATGGATTTAGCACGTTTNGGAAGCANGNGCTCNNATGATTTCAGTACTGTAGTGTCAGTNNTATTAGTTTCGNTCAGATCAATGTCTAGATCTATAGAATCNAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCNTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTAGTATAAAATTCTATATTCAAATTATCATGCGANNTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAANNAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGNTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCNTGTAATCATTCGAAATAANTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGNGGAATCAGTTANGAANAAAAAATTATCTGTCATCATCATCATCTATTNGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTNGATACATCACGACCNTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCNTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAANTTTTTATGGTATAGATCCNNTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTANCTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCNTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTNGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATNAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTANGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTANGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCNAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCNAATACTTNGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAANNAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAANCNGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTNGATCTGCGCNGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCNAAACAACATATACACATTTAATNAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTANGAGCCATCATTTCGGCTATCGACTTAATATNCCTCTTGTTTTCGATAGAAAATCTANNGAGNTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGNGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCNTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGNAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTNAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATNCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCNTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGNAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAANTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCNTTTTAAGCCAAAATATGGAAGCGAATGATCCGGNAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCNTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTNNTTCCACTGTCCAAAATGATGNCTCTGCCNTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAANTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTNCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTNNAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCNCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAANTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGNTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGNTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTNAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCNAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTNAAAAGTTGTCACAACAGGGTNGTTCGTAGATTTTANNGTATAACNGAGACATNNNTNNAAAGATAAACTTTNTGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTNNNTCGGTATCTACTTTATCTGCCGAATACAGTGCTNNNGNNAAAATTATAATNTTTNNNCTTTCGTATTCGTAATTNGTTCNCTTTTCATGTTCGNAAAAGTGAAACNTGCGGTTAAAATNGTTTATAACATTAATATTACTGTTNNNNNCTGNCGGATNAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTNNNNTCGTTAAACGCCTTTAGNAAAACTNNNGAAGAATATCTCAATGNGAGTTCCTGACCATCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTCATCTNCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCNNCGTAGTTTCCATGGGACTATANNNNNNTGTNNCCTNGAATNNNNNNTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCNNCCTGTAGATATGTGATNAAAATCGTCGTTTATAGGATAAANNCGTTTATCNNTTTGTTGNNNAAAGGATGAATTAATGTAATCATTCNNNTCTATCTTTAGTAGTGNTTCCNTATTAAAATTNTTAAAATAATTTAACAATCTAACTGACGGAGCCCNNNNTTNGTGTNAATCTAATTGGGACATTANNTTGTTAAAATATAAANNNTCTCCTAATATAACAGTATCTGATAANCTATNGGGAGNCATCCATTGATATTCANGGGATGAATCATTNGNAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCNTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTNCAATTGTTGCCTGTATTGTATTANAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTANGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCANTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAANCANNAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACNATGNNCGGNTTAATGTNNTATGTAACATTGAGTAAATNCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATNCAAACAATGTTTCTANCGGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNNCGAATCAGTAACTATGTTCANNTTTTTANNNGTANGACGTCTAGCCAGTATNGANNAGGATTTTCNAGATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTCTATGAGTTGTTNCAATAAATTATTTGTTGTGACTGCGTTCAAGNCATAAATTANNTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCNCTGATAGCAGTTTNAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCNTTTGTACCANTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTNAGAACATGTCTTCTATTCTNGAAAACGAAAACATCCTNNATNGACTCATTAAAACTTNTAACGNNCCNGNTTGTGTTTCNAATGCCTNNNNCAAGGANNTCAAGGATGCCATAGATNNTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGANTTTTTTATTAAATCAAATNGTCGGCTCTCTGGTTTACTACCCCAANGATAACAATAGTCTTGTAAAGATANNNNNNNNNNNNNNNNNNNNNNNNCCATCCAAATAANCCTANNANCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCNTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAANTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAANTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATANTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTNAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACANTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACNTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTANGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGNATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTNCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCNNNAAAAAATCNTTTTTNATTNNTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCNTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACNTATTCAGAGTTGTTGTTCAAATAGATNCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGNNNTGCGGACATTAAACGATTTGATGAGTTAGATATTAATNACNNNNATATATCTAATATAATTTATGAGGTGAACGATNNNACATTAGATACAATGGATGATATNAAGAAGTGTCAAATCNTTAACGAGGATACGNNGTATTATGTTAAGGAATACAATACATACCTGNTTTTGCACNAGTCNGATCCCATGGTCNNAGAGAACGGAATACTAAAGAAACTGTCATCNATAAAATCCAAGAGTAGACGGCTNNACTTGNTTAGCNAAAACATTNNNAANNNNTATTTNNACGGACAATTNGCTCGTCTAGGTCNNNTGTTNGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGNGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAANCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGNTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTNNAGAGATAATCTATATCATGTAGAAGAATTCTTNGATNAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTGATAAATGNNNACCGTTGCNACANNTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATANTTTAACCTGATGTNNTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAANNNGTAGGATATNAATATTATGGCCGCAACCGTTCCGCGNTTTGACGANNTGTANAAAAATGCACAAAGAAGAATTNTAGATCNAGNAACANNTTTNNGTAGAGGTCTNNNTAGACCGTTAATGNAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCNNTATAAANGTCCTATTNNCGTATATGAAGNAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTNCGGTAGATACGTATCATATCTTNNAAAGTTTTCNNNCCTTCCAACAAACGAGTTTATTANNNNNTTANTATTGACCTCCATCCCTATCTNNNATATCNTATTCTNGTTTNNAANNACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCNTGCGTTGGCTANGTATATACATCAAACAGGAGACTATNNGNCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTNGTCCCGTTCCAATAGGTATCNAAGATATAGATCACCCTAATCNTAGTAGAGCANNAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGNTTTTATTGNTTTACGTACCTGGGTATTCAATTACTACNNNNNNTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACNAAGAGCGACGTACAANTNTNNTAAATTATTTTATGCTTCNNAAAATGTAGGTCTTGAACCAAACATTCTTTGNAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATNGTTTNNAGNAAACTNNNTAAAATATTCTTTGATTGCTGCCGAGNTTAAAACTTNTATCGATAATTGTTTCNNNNGTTTTAATATTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAACCAAATACATATTANGGTTATCTGCGGATTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTATTAATCNGTCGTTCNAACTCCTTTGNTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCNGTNAACACNGAGTCGGTANNTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATNTCTATCGTCCATATAAAATGGATTACTTAATGTATTNGCNAACCGTAACATACCGTTNGATNNCTCNGNTCCATTTAGTACCNANNCNAGATACAATATCATTCTACGTCCTATGGANNTGCAACTCTTAGCCNAAGNGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTANNNTGNTTTAANNNNNTTTTATATNNNNNNNNNTNNNCCNAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTNNTGAAGCAAGAGTTGATTATTTATNNNTTCTTNCNATCTNTTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATNNNNNNNNNNNNNNNNNNNNNNNNNGATACAGACNNNTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGNTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCNNAGTATNGTCACCGATGAACGTCATTNNNNTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTNGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGANTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATNATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCNTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACANNNNNTCATTAATGANNGTAAACNNNAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGANCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTNAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGNTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATNTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTANTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCNAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTNGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACANTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGNAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATNTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTNCCCTGTCTGCAGCCATTTTTANGNTCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCNCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATNCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCNTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTNCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCNCAACATTNGAATAATACCGTTTGATATACCATTNGTACCNGAGATATAGCTTCCACTNGCACGAATATNNNTAATTGATAGACCTATTNCCCCTNCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCNATGCTATCATCGATCATGTTAAGTNGAAAACAGCTAGACATTTGGTGACGNGTNGTTNCCGCATTNAANAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAANTTTTAAAACCAAAATAGTTGTANGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCNGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTANNATGGCGGTGCCAGAAATTACCATCNAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTNNNTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTNNTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCNTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCNTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCNGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTNANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAATATTTCGATGATATACGGTAGTCTCTCNTTCNGACTTNTATAGCNTATTNCACAATACGAGTCATTATATACNCCNNAAAANNNAATNNNTAGTATNAAATCNGTATCGAATGGNNAAAACGAAATTATCGATATAGGNNTAGAANCNNGAACATTGAACGTATTAATACTTAATNNTTTTTCANNNNNAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTNNGACTTGATAGATATTAANGACGAATTGNAAATTANTTTTATNACCACNNGTGNNTCAGGANCNTNGTCGANNNCAGTTAACCAACCGAATGGAGTANNNNAAATATCATTAATATATGCNCTAGATATTAGTANNNNNNTTAANNCTTTGATTATCATCTNNTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGNNCATCCTCCNGAGTATTAATNGGTTTAGTAAACAGTCCANCGTTGCNATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCNNNCGNTTAAAGATNNNACCTCATCTAACGGAGACAANNTTNNNGTAGGNTTTNNAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACNTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCANTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGNAAAAGAATAGAAATNAAAATTATTATAATGGTGGAATTCAGTTNGAATATTGNCTCCNGAGTCATNAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTNCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACNTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCNTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGNGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGNAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTANGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCNAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCNAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGNAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTANTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCNTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACNTTTGTAGAATATTATTCNGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTNAAAATCAAAATCTAATGACCACATCNNTTTTTAGAGATGNAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGNAAAAANTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCNATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGNTTTGATCTACTATACTTTNAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTNCTTCGGCATTTCNNTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGANNCGTCTNNGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTANGGGTATACTTCNATAAGGTTTNTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTNGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGNGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTANNTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTANAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTNTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCNAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCNTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTNAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGNAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCNNGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCNGAAGTTAAAACTTTATCATCTNNTATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGNAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTNGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTNATTTGAATCCATCGATAGAAAAACANNTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTNGATAGATTTTTTNNANGATATCTTAGTGCNAAAGTATACATGTTAGAGAATATTCNAGTTATGAAAATAGNAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATNAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGNGTATTTNTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTANTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTNTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATANTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTNGCAACAATTGTAGATACCATTAATCACTGATTCCNNTTTCGATNNNGGACAATAGCACAATTGTTTAGCNNTNGACTCTANNTATNNAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATNAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTNTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCNTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTNCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAANCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACNGCACCCAATTGCTGTCGCACNTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGNTGATTTATTCGACTGGTGTCANGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTANNTCTCTTNNTNATATGGATACTAATTGTAGCTATTTAAATGNGTGCCGCANCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTNAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGNNAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTANNTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCNGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTANTAATCTTCTTTGGGCACATATACCAGTNTACCAGGTTCTNNNAACCTANTTACTGGTGCTCCTGTAGNATACNNNNNTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTANNACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGNAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCNGGGTTAATCTCACAACTTTACTGNTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATNCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCNGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCNAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTNAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGNAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATANTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGNAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATNCCACAGAACTAATGTATATTCTAGGTACTTNTGGACAACNNAGGATAGATNNNGAANCAGCAGAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATGGTTCTTCCAGGTGNCGCCAACANGGGNNANNTTAGTAAATTCNAGATTCCTATCTCTGACTATACGGGATATAACGACNTCAATCAAACNAAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTAGTTACGANNCAGAATCANTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTANNAGAGNNNCGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCNTAAAAAGTCAGAACCTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAANGAAACTATCTGATAAGATATCTTCTCNAAAGATCNAGGAGATAGNAGAAACNGNAGACNTTTAATTCTTATCNNNAACATANTTTTCNATGATCTGTCTTTTAAACGATNGATTTTNCACAAATGCGCCTCTCNANTCCCTCATAGAATGATNNACGNATNNANNNNATAGCATAGGTNATGANNCCTTATTTTTAGACATTAGATATNNNAAAATCATAGCCCNNCTTCTATTTACTNCTGCAACACAATGAACCAACACNGGCTCGNTTNGTTGATCACATNNNGANAAGAAGGCGGTCNCNTCGTCAAAANNNTTACTAATATCNGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATNNACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGNCAAGACATCAACACTTATANTTTTTGTTATTATATTGGCAATTAGTNNGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACNAGATATATGCGAATNAAAAATACNGTTAACGATTNNAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTNAAAAGGCGGCNAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCNAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCNANTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTNAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCNTTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATNCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTNAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACNTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTNAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAANTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACNTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTNNNNAAAAGATCNTNCAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATNAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATNCTATATATGNAAAAATAGCAACCNGTGTTTGATCATNCGCGTCAATATTCTGTTCTATCGTANTNTANAACAATCTTATATCNTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATANTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTNGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAANTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACNAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAANTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCNAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTNGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTNAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTNAGNTTNNATTATCTNNNGTACATGGTCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGATANNATAGTNNNNGNNAAGAAATCATTAGTGACGGAAAATCGTCTTCACNAAGAATGCTTGTTGAGACNATCAACAGAGGAACGTCATATNTTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAANTTTACGATAGACTTTAAGCTAAAATATTTTCTANGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCNCGCTATTAATCATCCNAAGTCAAGGCCTAATANATCTCTNGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTNTTTCTCCACCTATTAACGCACCTATAAAGACNTTTATGTTGCCTAAACAAGATATAGTAGGTCTNGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGNTACATCAAAAGGGTTGNATTGTTANTTTANACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTNAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTNGAGAGTCGTCTATCTTTATAGAGTATANNAAATTTACCAACGATANNNGCTTTNNNAAAGAATATGGTTCTNGTNNGATTGTGTNNTATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGNNATTNAGTNNGTTGTNGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCNAAGCATCAAAATAGGAGATGTCTTTANCGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGNAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCNNTAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCNNNGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCNANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAACNAAGTNNAAAGNTTATTANNNGCGCATCTACAATGGAAGATAGACCGTCTACAANAAACTTTTTCGAACTAAATAGAGGAGCCATTAAANNTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCNTTTCTNNNNNGTNAANAATANNATGGTATNGGTTCTGNTATNCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATNAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGNNATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCNAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTANTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTNNGAAATCACAATGACTTTATCAGATCNAAATTAACAAAATTAAANGAGCATGTANNTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTNAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTNGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATNGAAACAGCCGCTTAGAAATAAACGAGTANNTGTGTGTGGTATAGATCCGTATCCNAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACNAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTANGAGAAACAAAAAGTCACGCGATTTACTNGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATANGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGNAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTNGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAANCCTTGATAACNAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTNAAAAATATACNNGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGNAAAATAGAGAGCTGTATGNNAAAACATTATCTAGTTGNTTATGTGGTGCTACNNNANGATGTTTAACATTCNNNNTTGGAGAAACCGCAANNNNGAAGTCGACAACCAAACGTTTGTTAAAGTNNNCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAANTTTAACAGATGTATTNGANAAAGGACCTAATCCATTTATCGCTAATATGCATTTNNAAAGATCTGTANTCNGTAGNNNACNACCTGNTTTTGCATGTANNGGATCNAAGNNNNTTANATCNNNNNNNNNTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTNCAATAAAATTAATAATANAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATNAGAAGAATTGCCGTCGTGCGATTCAGAACACACNTTTCTCAACCTTCTGGTNNAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACNAAAAATATCATATTNCTATTATGAAACTATATCCTACACCGGAAGAGATTNCGGACTTTGCNTTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTNCNTTAATGACGGACCTCTNNNAAAAGGGATATATATTGTACGATAATGTGGTTANTCTTCCGTTGANTNCTNNNCAACAGAAAATATCCAAGTATTTTAATTNNNNNCTATTTGGNNACGATANNNANAGCTNNATCAATAGACATANGAANNNTNCCAATGTTAGTGATGAATATCTGCANNATATATTCATANNNGATANNTNATCTCCGTAAATATATGCCATATATTTATAGAATATATCACANATCTAAATGAATACCNGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGNTTATCTAGTTNGAANTATCATAGATGAGAACNGAAGCGTGTTATTGTTCCNNATTATNNGATCGGGTAAAACAATAATCGCTTTGTTGTTNNNCTTGGTAGCTTNCAGATTTNNAAAGGTTTACANTTTAGTANCGAACATCAACATCTTAAAAATTTTCAATTATAATATNGGTGTAGCTATGAACNTGTTTAATGACGAATTCATAGCTGNNNATATNNTTATTCATTCCACAACAAGNTTTTATTCTCTTAATTATAACGATAACGTNATTAATTATAACNGATTNNNNCNCTACAATAACTCTANTTTTATCGTTGATGAGGCACATNATATTTTTNGGAATAANNNNNNNGNACTTATGACCGTGATNNNAAATAAAAACAAGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTGAGATTATTAGTCGTGGTNNNNAAGNAATTCAGACACTTCTTAACGAACNCNGAGNGANNNTACNCNNNNATTTGNNTANNNNAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACNNNAGTAGTATATTGTCACATGTCTAAACNNCANNAGAAAGATTANNNGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATNAAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCACTTTNNNNNCTTCTNTAATTCNANATATGGTGGATTGGTAATTAAATATATCATGCTCNNNAATGGATATTCTGAATATAATGGTTCTCANGGNNCTAATCCACATATGATAAACGGCAAACCNAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTNTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCNTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCNTTGACATCNAAAANCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATAATTNTCGTATTAAGTATAACGACTNCAAGTTACTTNAAATGGTTACATCAGTTATAAAAAATAAANAAGACGCTANGAATTACATNNNNGATATTGTAAACGGTCACTTCTTTGTATCGAATNAAGTATTTGATAANNNNCTTTTATACAAATACGAAAACGATATTANTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTNGGGAGTTAANTNNNGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGNNATATAAAGAAATAAATGTCGAGCNTTGTTACCAATGGATATCTTCCAGTTACATTNGAACNNCATGAGNTGACGTTAGACATNAAAACTAATATTANGAATGCCGTATATAAGGCGTATNTCCATAGNNNAATNNGTGGTNAAATGGCCAAGNAAATAGAAATTCGTGAAGACGTGGAATTANNNNTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCNNNTGNANTAACCTACGCATATTATCACGTTNGGGATATAGTCAGAGGAACANNAAACATCGAAGATGAATCNAATGTAACTATTCANNNNNNAGATTTAANCTGTAAACTAAGTAGAGATTCNGGNACTGTATCATTTAGCGATTCNNAGTACNGNNTTTTTCGAAATGNNAANGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTNTCGCGAATATCGTTGACTNANAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTNCCTTCGATATATTTTTGATAATATGNAAAACATGCNNCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCNNATAATCTNCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTNTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCNGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTNGNAAAANTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACANTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGNTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAANCCTCCACTTATATATCCTCCTTTNAAATTAATCCTTACTAGTTTTCCAGTATTCTNGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCANAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGNGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTANTTNCNAGGATGACTNTCAAATTATTACNCNCACGGCANNNGNTAACCAATGCCTATNGTNTCANAAACNANTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGNAACAGACGAGATAGNTTTNTCTATTNNNAAATAATTAGAACTNNAAACATGTATNGAAAGNAACGATTATTTCTGAATTATTNCAATTATTTGAACAAACAGNNNNGAAGTATACTATCGTCANNTTTTTCTCNNGNTNCANNTACTGCTGATAATGATAGAATAAACGCNATTTATCCNNGTGGTATACCCAAAANNGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGNNAATATAGACANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAAGATACCATTATTAACAAANTTTTTGAGGTAATTTTCTTTGTTNGACGAATATNTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAANNTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTNAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATANTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCNTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCNTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCNGCGAGTTTAGCCNTTTGATAAATCTCTTCTTGCNTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTNCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGNTTTTTAACGCAATGGTCTTAGATNAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTNAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCNNGGATCTTNTATCAAAGCCNTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGNNNNNATATACAGTAGTCATTGNTTTACCGACACCTGNTTCATGGAACAATNAAAGAGAATGCATACTGTCTAATNCTNNGAAAACTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTNNACGGGCATATTAGTAGTTCTGCGTAAGGCATAANCGATATAGGCNNNNNGTGATTTACTCATTTATNNGNGNTNAGTAATAACTATGTTTTNAAAATCNNNNCAGTAGTTTNNCTAGNCTTNTCTNATGTNNNNTTTCGATACNTTTTGAATNNNAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTNGTATACTCTATTCGAAAACTCTAAGAACTTATTAATNAATTNCGTATCCACTGGATCGTTTNAAATNNTAAATTGAACAGTGTTCACATCCTTNCAAGACGAAGACTTAGTGNNGGACTTAACATGAGACATAAATNAATNCAAANTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCNTTCNNCCAACTANCGCNTACGCATTTTAACAGTCNAANANTTTTAAAGAGACTACAATATANTCTCNTNGTATCGATTNNACCTCTACCGAATAGAGTNGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAANGTTAACATCTTATAATCGCTAATGTATNGATTGNTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTNCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACNGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACANCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTNAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGNGAGTGCTTCTTCTTTANCGGGCTTAAAGACTGCTTTNNGTGCTGAAATAACCACATCTGGANNACTTACTNGCNNAGCCATTTAATTACGGAACTANTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACNAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGNTTTTTAGATCTCATATGTGCTNAAAAGTTTTCCCATACTAATTNGTTACTATTATTTTTCGTATANTTTTTAACAGTTTGAGGNTTTAGANTTTTAGTTACNGAAGTGATATCGAATATTTTATCCNAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCNAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCNTTTCTGTACTCNGATTCAGNTTNTCATCNTTTANNTGATTGATTATTTNAAAGACTAACTTATAANNCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGANNTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTNCAGAACATTGATGAGACAATAATCTCCGCAATACATTNNTCAAATGAATAAGTTTATTAGACACNNGGAAGNTTGNNNNNTTTTGTACCTTTGTACATTTTTGAAATACNGACTNNCNAAAAATACAATATTCATATCCTTGTTCAGATACNNTACCNNNATGTCTANAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTNCAATATTTTATATNAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATANTTTTANTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATNTTTTTCGTACCAACTCNTTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTANAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTANNTCNCGGATTGNAAACAGAAAGAGGATCGTACATCCAAGGTCCNTTTTCTGTAAATAGAATCGTATAATGTNCCTTCAAGAAGATATCNGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTANCCTATACATGATACCGTTTAGCNTGATTTCTGGTGATNCGTCAATCGGAGTATCATCTATNAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATANNCNTATTCTGANNTNNTTCTACATNAAACATCATTGCTCCATTAACGATAACANNNGAATGAACAGCNCTACCCATCACNNTAGTTCCCAATGGATCAANNTGTGTAACTNCAGAACATCTTCCATAGCCTATGTTANGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATNGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGNGTNCATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATNGGAAAGGAGTNGAAATNNCTCGNTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATNCTGAATAGTAAAGNTAGATNNNTCATACTTGTTAGTAGTTAGATATTNNGCAATTGNANTCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTACGTTTAGGTTTGGTACGTTGATTTCNANNCCCTGCTGATATNAAGTCATCGTCTACAATTTNGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAANNGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTNAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGANTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCNGNCTGAAGTTGACGCATATCNTTTTCAACACTNGACATGAGATCCNTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTNGATTTGGANTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGNNCATACAGTGGCCACAATANGAGGTTGAAGAGGTGTAACCGTTNGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCNTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTNGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATANGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTNCATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCNTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCANNNNNNNNNNNNNNNNNNNCATCCACGNTTTGATAAATCTATCNTTANCTNNTGAAATAACGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGATNACANNTTTTGTAAATGTAANGTANTTAGACGANAGATCTTCGTTNNAAAGTTTTNCATNTATNNNNAATNCATCGGTTGTTAACACCATTCCCGCGTCAGANTGAATANGAGTTTGAATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGATGNAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTNGAGGCCTCCGTAGAACTANGGGANGTAAATANAGATCNAACAACACCTATGATAAAGGAGAATANCGGNTTTATATCCCGTAGTNGNCGTCTATTNNCCCATANNNNTNNGGATNNNNNGANAAAACNNNCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAANTCAACTCNNNAGTATCCATCATCCAAGNAAAACNCGGATACCAGTCTNGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAGTTCANTATCTGAAATAACNNATAGATTTTATNNNNTTAATCNAAAATCTGATCTTGTTCAATGGNGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGNAAATGATTCACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAGCAAACGTGATNAGGATACGCTATTAAAACANTTTACTTATGACTGGNGTTAGAATTTATAGACGNNACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCNAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGANTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATNCTTCTNCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACNNNATGATTGTCTCAAGTCTNCAATCGTTTGTTTNGNNCGATTAGCTNCAGAGTNCAATGCTTGGCTAACTAGCATATTATTATCTTTNGAAATTGTATTCTTCAATGAGGCGTTTNNNATATCNNTGATTTCGTTAGTNATATTACAGTCTGANTNGGTTGTAATGTTATNCAACATATCNNNNNTGGATACGGTNCACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACNAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATANAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAANNCTNAANTAATCAANTTTTNNNNNNNGTTTTTACTACAACTAGTTTTCATCANNGTAGTGACGATGNNTTGTTTAGTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTGGTAACNTTGATAGCCGTAGATCTTTGTTCCNTCGCTAANNNGTTNANNAAATTAATAAAGAATTTGTTGTTTNNATTTATGTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGNTTATAATCTNATCATTGANNNNTACTCTGTTACCATTGTAATAAATTGGTACTCTATCNNNATCANCGACNNAGTACTGTTCATANATGATGAGATGTTTATATGTTGGCATANNNNNNNNNNNGACGTTTNGTAATGGCAANNNNNNNNNATTAACNNCATAATGTCTAGCAGCANCTGCGATGTTATAAGTGATGTCAAAGCNNGGTTNATCTTNNNNNNTTATATATTGTCTAACACCTATAANATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAANTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCNAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGNAAAAGCTGTGAGTATTAATAATANGGTTAGNTTNCGAACTAATGNNNNTTNGATGATNNNTAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACANTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACNAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCNNNAGGAAATATCATCACAACNNAATGAAGATCTNTTTCCAGNNNNNNNTTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTNGAGAGTTATTGATATCGGAACAACGTCAACAACNAGNAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTNTGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGNAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCNAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCNAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCNTTTTATTAGTGGGCATCTTTTTAGATGGTTTCNTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCNTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGNTTTTTAAGCTGTGGTGTAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTGCTTNNNCCACATAGAATAAANTAGCATTCCGACTGTGNNNATNNTACCNNGTATAAACGCCATAATACTNAATACTTNNCATGNNCGAGTNGGACTGGTAGACTTACTNNAGTCANNAAAGGCGANNATACACGNAAGAATCNNNAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTNCATTTAACTAATNAAAATTTTAAATCGCCGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTAATATCTANTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTNNNCNGCATNTTATAACTAACAGCAGCAACGGCTCGTAANNNNNTATCATTTACTAGACGAAAAGGTGGTNGGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACGTATAATGCNNNATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCNAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACANNATTTTGCCACGCTATCACTATCACCCNGGAGATAATCNTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCANNAGNATATTTTAAATNCTTAATATATTCANGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGNAAGAACTACATGGTTCTCCANGAATTAATACATATTGTTTAGCAAATTCAGGAACTATNAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTNCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTNAAAAAAATGACTTGTGGTCAGACCATAAGTCNTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATNAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTANTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATANTATTATTAATATTGCCAAGTTATCCGATCNNNAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCNGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACNATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCNAAAAAATAAAGTACATGATANGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTNGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACNNGTATTAAATAGAATATTTAANNNNCAAAATCNNNNNNAAGNTTNNNAGACGATCNNCATGCTGNGCNNGCCAGTGTATTANCCCTCATAGTATTAATATAATCCAATGATACNTTTGTGATGTNNGAAATNTTAACCAATTTAGACTGACAGGCANNACACGTCATACANNNATNATCGTCATCGATAANTNTAGTCNTGGGCTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCTGGTATANNGTCTCTATCTTTATNNCAATATAGTGTATCAACATCTTNNTTATTGACCTCNTTTATCTTNGAACATGGAATNGGNACATTTTTGTTAACNGCCACNNNTNCCNTAATTCCAGATGTTGTNAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTNTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTNAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAANNNNTTAGTCTGTACNAAAGTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGTAACTAATGTCNNGACGTCCATATCTGATTATTATGATGAGGTAAAAAANAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAANGGTAAAAATATGGTAGAACTTGGATCTGGAAACTNTTTTCAAATACCGGATNAGATTCNAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGANGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATNGTATAGGAGATAATNTTTTTATTCCTAGCGTTATAACAAAATCAGGNAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATNGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATNGACACTANNNGACGAGACTANTATGNNNNTGNNNANTANNNNNNNNNNGTTGGTATTGCAGGCNNNAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAANNNTCGATGAGTTAGTTGATGAGATTAATAAATCNNNAACTNTNAAACGAAAAANNAAAAACCAANCAGTATTTGATTTNAGNAGAGAATGNTTGGGATATCCNNNAGCNGANTTTATAACNNNAGTNNNTAACATNNNGTTCNNANNAGNAAATNNTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAANTATATANGGAAACNNCAACCANTTCGTCTCAATCTTTAATACCGTTACCGATGTCNAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCNAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGNAGGTCACCGTANNTCAAATTTATCTATTTTATTNAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTNTTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGNAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATNNNNNCATTCGGATTNCGAGANTNCGTTNCNGATAGACNNNNATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATNAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTNAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGNTTTNCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGNAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGNAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGNTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGANNNNTANATTTNCAATATGTATNNNNNNNNNNNNNNNNNNNNNNNNGATTGCANGAAATNTTGANNNNCAANCGGCCNCTCNTATCGTTTNANAATAATACAGAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACGCATTANCCACGTTCACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCNNGTTCNNNANNTCATAGGTGGAGNCTTTATCNNNNNACAATCNNNNNNAAAAGTANNNATTAATCTANTAGAAAAGATTACAACATGGCCAAAATTTANGGTTGTTNANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTCATTNGACGTAGTTTATCATACGNTATGCCTCNNNAAGTTGTCTATCTAGTAAANGCGATAATAGANANNGCTAANNNACTTANCGAATCTATTACTGACTTTNATATTGNNNNNTACATTAATGACCTGGTGNNAGCTGAACACNNNAAACNAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACNTTTTACCTCNNATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACNTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATNCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGNGTGGAAAGTTCNNAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTNCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGNAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCNAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATNNGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCNAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTNAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTNNAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGNNNACGTGGAGGAGGTATCAAGTTTGNAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCNNCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCNTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCNTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCNNATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCNTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCNATGCTTCCNNGNNATAGTCTGGAACACTAATGGGTGACGNAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGNGCGGCNGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATNNCATATCATATTNNAAAATCTTGATNGAAGNNCGAATATCTCGTCTGACNNAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTNCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGNTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGNTTTTCTACCTCAGTGGCGAAATCTTTGGNGTGTTTGGTACANTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGNTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCNTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCNAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCNTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAANAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTNAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATNAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCNAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATNGGAAATGTAATAGTAANTTTTTATCATAAAAGTTGTAAAGTAAATAANAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCNGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTNNAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTNTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGANTATTATACTCTGTATTAGTTCNGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGNAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATANNCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATNAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAANTTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCNTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTNAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCNTAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGNAGTTANTTACGTTGAACAAGTNCATGGNAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTNGAGGATGTGATTCCATAGGCAGTCNNNAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACANTTTCTTNNNATTAACGAGAATGGCGTTTNATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGANGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACNGAAATACTATATCNNNCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGANACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATNAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAANNTTTTTTATAGTATGAAGGNNNNGATGNNNNNNNNNATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATNAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTANTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTNAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATNAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTNGATAATCCATTTATNTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTANNNGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTNNNNNNAAATACNTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATANGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTNAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATANCCAATAGAATAGTATTCTCAGAGTTGACGAATANTNGTNNNGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTNNGACGATGAATNCGGTAAATGGNNGACGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCGATTTTGTAGTAGATGATNCGNAACAATCTCAGATATGGGAAATTTCAGGAGCAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNANGAAATAAATCATATNNAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTNAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCNTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCNAGACTACATTNNNGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATANNTTTTTTTAAGCACGAAATNAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTANGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCNNAAAGNAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGNGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTANTTTTTTCTGTAATAGTTANAAANNACNNNCGATGGTCTATCTACCAGATTATNNNNTGTTATAAGGTACTTTNNTCNTAATAAACTAGAGTATGAGTAAGATAGTGNTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTNAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATNAAAATGTNCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATANNTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGNAACATACGATAAAGNAAAAGATTGTTGGACATTNGATAATGGTCACTTGTTACCACATAATTATATAATGNNTAAATGCGAACCGTTTNAACATAGATATCCATTNNNNAAAANACAGTACACGAATGATTTTCNNNAGTATTTNNNAAGNTTTATANNNAGTTNATAGAACAAAATACATNANTTTGTNAAAATAAATCACNTTTTATACTAATATGNNACAATTANCAATACTTTTGTTACTANNNNCNNTAGTATACGCTACACCTNNTCCTCNGANATCTNAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATNAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTNNANNCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCNAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTNNNTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTNTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACNATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGNTTTATACAAATCCATTAATGTNGAATATCGATTCTTNGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAANAATAATAGACTACCAGNAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGNAATATAGTCTTGGATCAAATAGATAAGAATAAANTATATCTAGTGGATTACGGATTGGTTTCTAAANTCATGTCTAACGGCGAACATGNTCCNNNNATAAGAAANCCAAATNAAATNGATNNNNGTACTCNAGAATTTACACCTATAGATTCGCATNAANNATACNNNNNNNNNAGACGTGGTGATCTAGAAACANNNNGATATTGTANGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAATTGCNNNAATATATTANNATGGTANNNNNNNNNACATATTTTGAGGAACCNAATTACGACNANNTTNNNNNNNTNTTNNNNNNNNGANNTNNNNNAAATTTTTNTNGATNNAANNNNNNNAAAAATAACTNNGTTATTATCANNCTCGTGAGNANAATNGAAACANNNNGNNGNNNNACGNNCACGCTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCATCGACNGTTGCCNNNNNNGTCANGAAATATTCTGTTGTGTCAGTTTATAATNAAAAGTATAACATTGTAAAAAACAAANATATGTGGTGTAACAGTCAAGNGAACAAGAGATATATTNGAGNNNNNNNNNNNNNGTNTGAATGCAATGAATATCTACAAATTGGAGATNCAATCCATGATCTAGAAGGAAATCAAATNTNTATTGTCACATATCGCCACAAAAACNACNATGNTCNAAGTGGAANNNNNNACGAGAGTCTAGANNTGTGNTTGGAANGAGTANGGATNNNTCATCACGTACTTGAAACAGGAANNNNGGTATATGGAAAAGTNCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGNGNCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCNNTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGNGAAAGACACTGAATCAATNGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATNGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGANTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACNTTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATNNAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGNTTTTTGTATCAAAGACATTAATACTTTAATGAGATACNGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATNCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAATACTTNNNNGAATGATANNNTCNCGTGTCCTANNNNNNNNNNNNNNNNNNNNCNNTTAGAACACNGATCNTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCCAACANNTGTACGATCTAACGAAGAATTTGATCCAGTNGATGATGGTNCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATNAGCTAGAATCAATTAGATGTCTTCTTCAGTNGATGTTGATATCTACGATGCCGTTAGAGCANTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTNGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACANTTAATGGTATAATGATGAATGAATTCGATACNGTATGNGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTNTAGCTAATNNGAGATATNGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATNAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGNTGCATCCTATTCGAATAATGAGTACANNCCGTTTAATAAACTGAGTGTNAAACTCNATATNGANNGAGTAGATAATATAGNAAATNNNNATACTGATGATAATAATNAANNNGTGTTANNNNNTNAANAGTNNACNNTTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCANAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCNAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACNTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCNATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGANNNAACATNGGGNTTAAAAATANGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACNGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACNCAACAAACACGTCTTGGATCATCNCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCNAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCNGGAGACATAAAATTTGAGGAGNATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTTAACAATTNGTTCTGATCTACAGACANNNNTTAATAAATCANCTTATTTTNCCAANATATTAAAANNNNNNNACNNCACNNNTNNNNNNNNATTGTGCGNCTTTCAAGATGATGNNNNATATAGGGTNNTACAGTTTTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAAATTATTTGNNTAGAATATTACGNNTATAATTGTTTNGAAATTTATAGAATAACNNNTATTAATACATTATNGTATATCTACAACGNTATNAGNNNCTTCATATTNGATAATATTACTANTAATATNNNNGGATNCAGANTTNNNNNNNTTGCCTAAATACATNNTTATAGNNTTACNNNGACAATCACCTAAATGTTTTNNACGNAGATAANNNGGTAAAGATTATNNNNACTTNTANNNCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATANNTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATNGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATANAGATGTAGAAGATATCATGAATGAAATAGATAGAGANAAAGAAGAAATACTNAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTANAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCNCGATGTAGGAATATAGANCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGNTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATNGATCATAAATCACNCAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCNTTGACTATCAACAACTGGACACGAGAANNTGGTATAAANNATTTGGCTATTNCAGATCTGNNTNNAATTGGAGAAACCGATGATTATATGTTCNTCATTATAANNAATTTGGGAAGAGNANTCGCCCCAAAGGATNGTGAATCAGNNTTCGAAGCATGTGTCACTATGATNAACACGTTNGAGTTTATACACTCTCAAGGATTTACTCATGGNAAAATNGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGANGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTNCATGGNNAAACGAAAGTAGTATNNAAGTAATAAAACNNAAAAAAGAATATAAACAATTTATAGCTACNTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAANTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATNNTANNCNNNTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCNAATATTAATATTAGACTATCTCTANCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCANCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATNNCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNNNCTTTAAAGCNNAATNGTTGATGCCATTCGAAANNGAATTTACCAGTGATTATCCCNNNNACGTATCTCCNNNNNAAATNGTAGNNGNNNGNATNATGTCTATTTNCGGCGAGCCANTTAATCACGCATCTNNNNNNNAATCATTCNGNAACNNNNCAATCATAGAACTGCCATATGTTGGNGATNCTAGTATGATGGNCATTCTTCCNAACAAGATTGATGGATTAGAATCCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATAATCTTGTNNATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGNGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGANGNGTATACAGAAGCAGCTGCAGCAACTTCNGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCNTTTCGTTGGTAGATATTGCTNTNCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACANNTTTTTTTAAAAATAGNAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTNGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTNGATNTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGNNNNNNNNANNNNNNNNNNNNNNNNTTTAAAGATGATGNGGAATCAGTNNNNATCGACGTNCGTGAGCTGGNNAAAAATATGCCGTGGGATAATGTTNAGGATTGTACAGAGATCATCCGTTGTTATANANNGGATGAGCNAAAANNNATCNNNNAGATTTCGGCCATCATTGGANTTTNTNNATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACNTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATANTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGANNATATATATATATATATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACNTCAATAGGTNGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTNGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACNNTATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGANCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGNTCTCNGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATNGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTNTACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTNAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATNAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTTTAGATANCNNTAGATCACTTGATGGGTANGATATTAATTGTTACTTNNNNNGACGTACACCACTTCATTGCGCTATACAATATNNNNNNACNCAGATTGCTGANTACTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTGATTAGTCGTCTACCGCCTAAAAGNGTNATATGCTCACTGACTAACCATATAATAGATTATGTTCNTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTANNAAGTACGTACTGTTACTGGACCCATCNNNNTATTATAGANTCAGNAATGTTATCGNNNACAAATTAGACCAATACAATAATCGTTATAATATNTTCGAACACGATANNGACGTTAANNNNNNNTATGGCAAAGTCNTACATGANCTNGATACATATATCNAGGNNGTNNAAGTATTAAAATCTACTTCCATCNNNAATAATATAACACTATACGACACNNNTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAANCTNATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTANAGAAATATACTTTAACTNATATAGTCCTNNAGNATATGATCTCATCTCNNTCTCAATCATCTTATTTGAGTCGTATTNCTAATGAGANNNTACTCGAAATATTATATAAANTCGACATGTACGATTTANNNNNNNNNNNNNNNNNNNATATNNGAGAGAATGATATCACAGAGTATCATATNNAGAATACGANGTCTGTTTCTNNANNGACATGAATAATGANNACACATNNAACNNNNTTTTTAATCTTNGATATAACACTAATTACATCNAGATTATATATTNAAATCGTAATTTGAGTTGTCTGATCNNCATGNNNNNNNNAAANNATATACNNAACATNNGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATATAGAGAATATGAATGAGAATACANCCGATGATNAGNAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACNAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGNAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTANAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTNAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCNAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCNAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATNGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGNAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGNTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATNCATAAAAATGACACTGTTGACAATAACACNATGGTTGATNANGNGACANCTAACAATAACACATTACATGGTAATATAGGANTTTTNGAAANAAATAATTGTTATANNNTTTCNGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACANGAACNAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTNATGGCATCCGTTATTCCTGCAGTTAANGAANTTAACAATACGTTGATGAAAATTGGTGTNAAAGATNATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTNTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTANNNACAATAGTGTTTCGACNNCTAACAGCAGNAAAAGACGAGATCTGAATGATGAGTTTGAATTTTNCACTTNCNAGGAATTAGATTGTCTTTACGAATCNTATGGTGTAAANNATGATATAAGTCATTGTTTTGCATCACCTAGACNNNGACGATCNGACGACNAAANNNNGTACATGGACNNGNAATTATTCNACNNCGNNNANNNNNANTTNGGAATAGACAGTGTTATTNCTNGANGTACAACCCATTTNCAAGTANGTGCATCTGGTGCNNNTGGTGGTGTTGNAGGAGATAGNTTNNCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGNAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCNAAAGCTTTCTAATGTTNGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCNAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTNCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTNAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATNAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTNAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCNGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATNTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTNACAAAATCCATTTAGACAAGAAGGGACATATAAGCNACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAANCTATGATATTGGAAGATGTATNATNGTGTAGTTCTAGAACTAGNAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTNTTACAGCAACCTCCTTNNACATTCGAATTCATTCNTGACAATTCTAACGAATATGTGGATANAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGNCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACNAAGATATAAAAGACATTATAGAATCCGAAGAANGTAAGAGATNNNNTATAATAGATGTTANNAACAATCTTGTTNNAAAGTACTATTNTATTGATAATTATCNNTGTNATACTTTAGATGATTATATATACANCTCTGNAGAATATAACAANNNCTNTNTGTTAGNAAACGATACTTNTATANGCNNNNACTATCNTGAATCATCAGNNGTANNNGTTNTATCATNTTATGAAANGACTANAATCTCCTTNGATACNAAAGACGCCAAAGATGCTATAGAAGATGTGANNNTAGCNAGTGCNGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATNAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGANNTTTTTTAAATGAGTATCGGTAGTTACANNNTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTANCNNGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGNTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGNNCACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGNGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAANGGTACTTATNCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTNATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCNNGATTTTCGCATTGACTTTACACAGACATGAACATNCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAANGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTNCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCNAAAACTCACTTTTGANTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATNAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATNNAANTGATATAACNAATACAGCAGATATATTGCTNGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGNAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATNAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGNNAGTTAAGTNNTNNGTTAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGNNNNAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATNAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGNACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTNGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATNTTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTNCATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCNGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAANNAAAGTGTGGAATAGGATACGGAGTATCCGGNTACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTNCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTANNAACTTCAGGATTCTTTACNGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTNGNNNNNNNNNNNNNNAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTNTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATNCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGNNAGNTNCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGANNTATCCGAAGAAGTTGTNAAAGGAGATCCCACCACTTATTACACTATCGTCNGTGCGGGTCTTNNNATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACANTGTGAATACTAGATTGTCCAGCGTGTCACCNGGACAAGGTAAGGANNCTNCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATNCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGNTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGNNCGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCNNCGGATCGGCATCTGAAGGTGCAACCGATGATACTTNACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGNAAATGGATGAGTTNGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACNAAAATATTTAACTACATTCACAAAAAGTTANNNCTCGTTACTTCTTCNTTCTGTTTCAATATGTGATACGATATGATCACTATTCNTNTTCTCTTGGTCTCATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +>Monkeypox/PT0008/2022|sampling_date_20220515 +TAATTAATTTAATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTTGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTANTAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTTGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGAGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTNNANNNNNNNNNNNNNNNNNNGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGAGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTAAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAAAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATTAAATTAATTA +>ON676708 +ATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATTATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGTTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTTTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGNNNNATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATNNNAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAAT +>ON843165 +TAATTAATTTAATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTTTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTTGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGAGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGAGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGNNNNNNNNGCNNNNNNNNNNNNNTTTCACGACGACCTCGATCNNNNNNNNNTNNCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATTAAATTAATTA diff --git a/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/tree.json b/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/tree.json new file mode 100644 index 00000000..2e510251 --- /dev/null +++ b/data_output/nextstrain/mpox/clade-iib/rivers/unreleased/tree.json @@ -0,0 +1 @@ +{"version":"v2","meta":{"title":"Nextclade reference tree for HPXV-1 (reference seq: NC_063383.1)","updated":"2023-11-16","build_url":"https://github.com/nextstrain/monkeypox","data_provenance":[{"name":"GenBank","url":"https://www.ncbi.nlm.nih.gov/genbank/"}],"maintainers":[{"name":"Nextstrain team","url":"http://nextstrain.org"}],"display_defaults":{"color_by":"lineage","map_triplicate":false,"distance_measure":"div","tip_label":"strain_display","transmission_lines":false},"genome_annotations":{"OPG001":{"end":1575,"seqid":"resources/genome_annotation.gff3","start":835,"strand":"-","type":"gene"},"OPG001_dup":{"end":196375,"seqid":"resources/genome_annotation.gff3","start":195635,"strand":"+","type":"gene"},"OPG002":{"end":2751,"seqid":"resources/genome_annotation.gff3","start":1702,"strand":"-","type":"gene"},"OPG002_dup":{"end":195508,"seqid":"resources/genome_annotation.gff3","start":194459,"strand":"+","type":"gene"},"OPG003":{"end":4607,"seqid":"resources/genome_annotation.gff3","start":2841,"strand":"-","type":"gene"},"OPG003_dup":{"end":194369,"seqid":"resources/genome_annotation.gff3","start":192603,"strand":"+","type":"gene"},"OPG005":{"end":189660,"seqid":"resources/genome_annotation.gff3","start":189199,"strand":"+","type":"gene"},"OPG015":{"end":6156,"seqid":"resources/genome_annotation.gff3","start":4843,"strand":"-","type":"gene"},"OPG015_dup":{"end":192367,"seqid":"resources/genome_annotation.gff3","start":191054,"strand":"+","type":"gene"},"OPG016":{"end":190940,"seqid":"resources/genome_annotation.gff3","start":190410,"strand":"+","type":"gene"},"OPG019":{"end":8008,"seqid":"resources/genome_annotation.gff3","start":7580,"strand":"+","type":"gene"},"OPG021":{"end":10315,"seqid":"resources/genome_annotation.gff3","start":9587,"strand":"+","type":"gene"},"OPG022":{"end":10858,"seqid":"resources/genome_annotation.gff3","start":10478,"strand":"-","type":"gene"},"OPG023":{"end":12900,"seqid":"resources/genome_annotation.gff3","start":10918,"strand":"-","type":"gene"},"OPG024":{"end":13228,"seqid":"resources/genome_annotation.gff3","start":13034,"strand":"-","type":"gene"},"OPG025":{"end":15267,"seqid":"resources/genome_annotation.gff3","start":13375,"strand":"-","type":"gene"},"OPG027":{"end":16377,"seqid":"resources/genome_annotation.gff3","start":15925,"strand":"-","type":"gene"},"OPG029":{"end":17069,"seqid":"resources/genome_annotation.gff3","start":16602,"strand":"-","type":"gene"},"OPG030":{"end":17833,"seqid":"resources/genome_annotation.gff3","start":17213,"strand":"-","type":"gene"},"OPG031":{"end":18828,"seqid":"resources/genome_annotation.gff3","start":17878,"strand":"-","type":"gene"},"OPG034":{"end":20005,"seqid":"resources/genome_annotation.gff3","start":19361,"strand":"-","type":"gene"},"OPG035":{"end":20404,"seqid":"resources/genome_annotation.gff3","start":20051,"strand":"-","type":"gene"},"OPG036":{"end":21064,"seqid":"resources/genome_annotation.gff3","start":20531,"strand":"-","type":"gene"},"OPG037":{"end":22433,"seqid":"resources/genome_annotation.gff3","start":21105,"strand":"-","type":"gene"},"OPG038":{"end":23159,"seqid":"resources/genome_annotation.gff3","start":22497,"strand":"-","type":"gene"},"OPG039":{"end":24118,"seqid":"resources/genome_annotation.gff3","start":23264,"strand":"-","type":"gene"},"OPG040":{"end":25478,"seqid":"resources/genome_annotation.gff3","start":24351,"strand":"-","type":"gene"},"OPG042":{"end":27097,"seqid":"resources/genome_annotation.gff3","start":25823,"strand":"-","type":"gene"},"OPG043":{"end":27955,"seqid":"resources/genome_annotation.gff3","start":27125,"strand":"-","type":"gene"},"OPG044":{"end":28540,"seqid":"resources/genome_annotation.gff3","start":28091,"strand":"+","type":"gene"},"OPG045":{"end":29262,"seqid":"resources/genome_annotation.gff3","start":28603,"strand":"-","type":"gene"},"OPG046":{"end":29729,"seqid":"resources/genome_annotation.gff3","start":29274,"strand":"-","type":"gene"},"OPG047":{"end":31194,"seqid":"resources/genome_annotation.gff3","start":29746,"strand":"-","type":"gene"},"OPG048":{"end":32164,"seqid":"resources/genome_annotation.gff3","start":31205,"strand":"-","type":"gene"},"OPG049":{"end":33151,"seqid":"resources/genome_annotation.gff3","start":32195,"strand":"-","type":"gene"},"OPG050":{"end":33408,"seqid":"resources/genome_annotation.gff3","start":33181,"strand":"-","type":"gene"},"OPG051":{"end":33649,"seqid":"resources/genome_annotation.gff3","start":33425,"strand":"-","type":"gene"},"OPG052":{"end":33995,"seqid":"resources/genome_annotation.gff3","start":33801,"strand":"-","type":"gene"},"OPG053":{"end":34690,"seqid":"resources/genome_annotation.gff3","start":34052,"strand":"-","type":"gene"},"OPG054":{"end":35996,"seqid":"resources/genome_annotation.gff3","start":34677,"strand":"-","type":"gene"},"OPG055":{"end":37083,"seqid":"resources/genome_annotation.gff3","start":36019,"strand":"-","type":"gene"},"OPG056":{"end":39034,"seqid":"resources/genome_annotation.gff3","start":37127,"strand":"-","type":"gene"},"OPG057":{"end":40195,"seqid":"resources/genome_annotation.gff3","start":39077,"strand":"-","type":"gene"},"OPG058":{"end":40434,"seqid":"resources/genome_annotation.gff3","start":40213,"strand":"-","type":"gene"},"OPG059":{"end":40633,"seqid":"resources/genome_annotation.gff3","start":40484,"strand":"-","type":"gene"},"OPG060":{"end":41182,"seqid":"resources/genome_annotation.gff3","start":40706,"strand":"-","type":"gene"},"OPG061":{"end":41884,"seqid":"resources/genome_annotation.gff3","start":41189,"strand":"-","type":"gene"},"OPG062":{"end":42252,"seqid":"resources/genome_annotation.gff3","start":41947,"strand":"+","type":"gene"},"OPG063":{"end":43688,"seqid":"resources/genome_annotation.gff3","start":42249,"strand":"-","type":"gene"},"OPG064":{"end":45898,"seqid":"resources/genome_annotation.gff3","start":43685,"strand":"-","type":"gene"},"OPG065":{"end":46483,"seqid":"resources/genome_annotation.gff3","start":46022,"strand":"-","type":"gene"},"OPG066":{"end":47428,"seqid":"resources/genome_annotation.gff3","start":46649,"strand":"-","type":"gene"},"OPG068":{"end":49904,"seqid":"resources/genome_annotation.gff3","start":48201,"strand":"+","type":"gene"},"OPG069":{"end":50486,"seqid":"resources/genome_annotation.gff3","start":49986,"strand":"+","type":"gene"},"OPG070":{"end":51411,"seqid":"resources/genome_annotation.gff3","start":50590,"strand":"+","type":"gene"},"OPG071":{"end":54438,"seqid":"resources/genome_annotation.gff3","start":51418,"strand":"-","type":"gene"},"OPG072":{"end":54757,"seqid":"resources/genome_annotation.gff3","start":54470,"strand":"+","type":"gene"},"OPG073":{"end":55141,"seqid":"resources/genome_annotation.gff3","start":54752,"strand":"-","type":"gene"},"OPG074":{"end":57125,"seqid":"resources/genome_annotation.gff3","start":55128,"strand":"-","type":"gene"},"OPG075":{"end":57498,"seqid":"resources/genome_annotation.gff3","start":57172,"strand":"-","type":"gene"},"OPG076":{"end":57630,"seqid":"resources/genome_annotation.gff3","start":57523,"strand":"-","type":"gene"},"OPG077":{"end":58583,"seqid":"resources/genome_annotation.gff3","start":57645,"strand":"-","type":"gene"},"OPG078":{"end":58811,"seqid":"resources/genome_annotation.gff3","start":58590,"strand":"-","type":"gene"},"OPG079":{"end":59621,"seqid":"resources/genome_annotation.gff3","start":58812,"strand":"-","type":"gene"},"OPG080":{"end":62018,"seqid":"resources/genome_annotation.gff3","start":59703,"strand":"-","type":"gene"},"OPG081":{"end":62285,"seqid":"resources/genome_annotation.gff3","start":62046,"strand":"-","type":"gene"},"OPG082":{"end":63452,"seqid":"resources/genome_annotation.gff3","start":62304,"strand":"-","type":"gene"},"OPG083":{"end":64716,"seqid":"resources/genome_annotation.gff3","start":63445,"strand":"-","type":"gene"},"OPG084":{"end":66752,"seqid":"resources/genome_annotation.gff3","start":64722,"strand":"+","type":"gene"},"OPG085":{"end":68531,"seqid":"resources/genome_annotation.gff3","start":66756,"strand":"-","type":"gene"},"OPG086":{"end":68863,"seqid":"resources/genome_annotation.gff3","start":68528,"strand":"-","type":"gene"},"OPG087":{"end":69519,"seqid":"resources/genome_annotation.gff3","start":68857,"strand":"+","type":"gene"},"OPG088":{"end":69863,"seqid":"resources/genome_annotation.gff3","start":69489,"strand":"-","type":"gene"},"OPG089":{"end":71170,"seqid":"resources/genome_annotation.gff3","start":69866,"strand":"+","type":"gene"},"OPG090":{"end":71370,"seqid":"resources/genome_annotation.gff3","start":71179,"strand":"+","type":"gene"},"OPG091":{"end":71867,"seqid":"resources/genome_annotation.gff3","start":71370,"strand":"+","type":"gene"},"OPG092":{"end":72947,"seqid":"resources/genome_annotation.gff3","start":71832,"strand":"-","type":"gene"},"OPG093":{"end":73760,"seqid":"resources/genome_annotation.gff3","start":72978,"strand":"+","type":"gene"},"OPG094":{"end":74802,"seqid":"resources/genome_annotation.gff3","start":73780,"strand":"+","type":"gene"},"OPG095":{"end":75555,"seqid":"resources/genome_annotation.gff3","start":74803,"strand":"+","type":"gene"},"OPG096":{"end":75865,"seqid":"resources/genome_annotation.gff3","start":75587,"strand":"+","type":"gene"},"OPG097":{"end":76875,"seqid":"resources/genome_annotation.gff3","start":75841,"strand":"-","type":"gene"},"OPG098":{"end":77655,"seqid":"resources/genome_annotation.gff3","start":76900,"strand":"+","type":"gene"},"OPG099":{"end":78051,"seqid":"resources/genome_annotation.gff3","start":77665,"strand":"+","type":"gene"},"OPG100":{"end":78466,"seqid":"resources/genome_annotation.gff3","start":78008,"strand":"+","type":"gene"},"OPG101":{"end":79019,"seqid":"resources/genome_annotation.gff3","start":78486,"strand":"+","type":"gene"},"OPG102":{"end":80086,"seqid":"resources/genome_annotation.gff3","start":79085,"strand":"+","type":"gene"},"OPG103":{"end":80558,"seqid":"resources/genome_annotation.gff3","start":80001,"strand":"+","type":"gene"},"OPG104":{"end":81019,"seqid":"resources/genome_annotation.gff3","start":80618,"strand":"-","type":"gene"},"OPG105":{"end":84986,"seqid":"resources/genome_annotation.gff3","start":81126,"strand":"+","type":"gene"},"OPG106":{"end":85498,"seqid":"resources/genome_annotation.gff3","start":84983,"strand":"-","type":"gene"},"OPG107":{"end":86081,"seqid":"resources/genome_annotation.gff3","start":85512,"strand":"+","type":"gene"},"OPG108":{"end":87059,"seqid":"resources/genome_annotation.gff3","start":86085,"strand":"-","type":"gene"},"OPG109":{"end":89447,"seqid":"resources/genome_annotation.gff3","start":87060,"strand":"-","type":"gene"},"OPG110":{"end":90264,"seqid":"resources/genome_annotation.gff3","start":89632,"strand":"+","type":"gene"},"OPG111":{"end":91209,"seqid":"resources/genome_annotation.gff3","start":90265,"strand":"+","type":"gene"},"OPG112":{"end":91687,"seqid":"resources/genome_annotation.gff3","start":91247,"strand":"+","type":"gene"},"OPG113":{"end":94268,"seqid":"resources/genome_annotation.gff3","start":91731,"strand":"+","type":"gene"},"OPG114":{"end":94667,"seqid":"resources/genome_annotation.gff3","start":94227,"strand":"-","type":"gene"},"OPG115":{"end":95361,"seqid":"resources/genome_annotation.gff3","start":94660,"strand":"+","type":"gene"},"OPG116":{"end":96017,"seqid":"resources/genome_annotation.gff3","start":95361,"strand":"+","type":"gene"},"OPG117":{"end":98406,"seqid":"resources/genome_annotation.gff3","start":96049,"strand":"+","type":"gene"},"OPG118":{"end":100359,"seqid":"resources/genome_annotation.gff3","start":98446,"strand":"+","type":"gene"},"OPG119":{"end":100871,"seqid":"resources/genome_annotation.gff3","start":100386,"strand":"+","type":"gene"},"OPG120":{"end":101748,"seqid":"resources/genome_annotation.gff3","start":100834,"strand":"-","type":"gene"},"OPG121":{"end":102431,"seqid":"resources/genome_annotation.gff3","start":101790,"strand":"+","type":"gene"},"OPG122":{"end":103174,"seqid":"resources/genome_annotation.gff3","start":102428,"strand":"+","type":"gene"},"OPG123":{"end":105070,"seqid":"resources/genome_annotation.gff3","start":103175,"strand":"-","type":"gene"},"OPG124":{"end":105968,"seqid":"resources/genome_annotation.gff3","start":105105,"strand":"-","type":"gene"},"OPG125":{"end":107654,"seqid":"resources/genome_annotation.gff3","start":105999,"strand":"-","type":"gene"},"OPG126":{"end":108130,"seqid":"resources/genome_annotation.gff3","start":107678,"strand":"-","type":"gene"},"OPG127":{"end":108825,"seqid":"resources/genome_annotation.gff3","start":108151,"strand":"-","type":"gene"},"OPG128":{"end":109055,"seqid":"resources/genome_annotation.gff3","start":108822,"strand":"-","type":"gene"},"OPG129":{"end":111004,"seqid":"resources/genome_annotation.gff3","start":109070,"strand":"-","type":"gene"},"OPG130":{"end":111902,"seqid":"resources/genome_annotation.gff3","start":111057,"strand":"-","type":"gene"},"OPG131":{"end":112425,"seqid":"resources/genome_annotation.gff3","start":111940,"strand":"+","type":"gene"},"OPG132":{"end":113540,"seqid":"resources/genome_annotation.gff3","start":112422,"strand":"-","type":"gene"},"OPG133":{"end":115696,"seqid":"resources/genome_annotation.gff3","start":113564,"strand":"-","type":"gene"},"OPG134":{"end":116628,"seqid":"resources/genome_annotation.gff3","start":115750,"strand":"+","type":"gene"},"OPG135":{"end":116911,"seqid":"resources/genome_annotation.gff3","start":116609,"strand":"-","type":"gene"},"OPG136":{"end":119587,"seqid":"resources/genome_annotation.gff3","start":116912,"strand":"-","type":"gene"},"OPG137":{"end":120558,"seqid":"resources/genome_annotation.gff3","start":119602,"strand":"+","type":"gene"},"OPG138":{"end":121132,"seqid":"resources/genome_annotation.gff3","start":120560,"strand":"-","type":"gene"},"OPG139":{"end":121368,"seqid":"resources/genome_annotation.gff3","start":121156,"strand":"-","type":"gene"},"OPG140":{"end":121746,"seqid":"resources/genome_annotation.gff3","start":121474,"strand":"-","type":"gene"},"OPG141":{"end":121924,"seqid":"resources/genome_annotation.gff3","start":121763,"strand":"-","type":"gene"},"OPG142":{"end":122198,"seqid":"resources/genome_annotation.gff3","start":121914,"strand":"-","type":"gene"},"OPG143":{"end":123315,"seqid":"resources/genome_annotation.gff3","start":122182,"strand":"-","type":"gene"},"OPG144":{"end":123932,"seqid":"resources/genome_annotation.gff3","start":123318,"strand":"-","type":"gene"},"OPG145":{"end":125425,"seqid":"resources/genome_annotation.gff3","start":123947,"strand":"+","type":"gene"},"OPG146":{"end":125639,"seqid":"resources/genome_annotation.gff3","start":125406,"strand":"-","type":"gene"},"OPG147":{"end":125987,"seqid":"resources/genome_annotation.gff3","start":125640,"strand":"-","type":"gene"},"OPG148":{"end":127266,"seqid":"resources/genome_annotation.gff3","start":125986,"strand":"+","type":"gene"},"OPG149":{"end":127759,"seqid":"resources/genome_annotation.gff3","start":127196,"strand":"+","type":"gene"},"OPG150":{"end":128927,"seqid":"resources/genome_annotation.gff3","start":127779,"strand":"+","type":"gene"},"OPG151":{"end":132418,"seqid":"resources/genome_annotation.gff3","start":128924,"strand":"+","type":"gene"},"OPG153":{"end":137667,"seqid":"resources/genome_annotation.gff3","start":136138,"strand":"-","type":"gene"},"OPG154":{"end":138050,"seqid":"resources/genome_annotation.gff3","start":137718,"strand":"-","type":"gene"},"OPG155":{"end":138491,"seqid":"resources/genome_annotation.gff3","start":138051,"strand":"-","type":"gene"},"OPG156":{"end":139409,"seqid":"resources/genome_annotation.gff3","start":138492,"strand":"-","type":"gene"},"OPG157":{"end":139608,"seqid":"resources/genome_annotation.gff3","start":139372,"strand":"-","type":"gene"},"OPG158":{"end":139769,"seqid":"resources/genome_annotation.gff3","start":139641,"strand":"-","type":"gene"},"OPG159":{"end":140205,"seqid":"resources/genome_annotation.gff3","start":139768,"strand":"+","type":"gene"},"OPG160":{"end":141074,"seqid":"resources/genome_annotation.gff3","start":140172,"strand":"-","type":"gene"},"OPG161":{"end":141647,"seqid":"resources/genome_annotation.gff3","start":141102,"strand":"+","type":"gene"},"OPG162":{"end":142158,"seqid":"resources/genome_annotation.gff3","start":141652,"strand":"+","type":"gene"},"OPG163":{"end":142732,"seqid":"resources/genome_annotation.gff3","start":142202,"strand":"+","type":"gene"},"OPG164":{"end":143464,"seqid":"resources/genome_annotation.gff3","start":142778,"strand":"+","type":"gene"},"OPG165":{"end":144322,"seqid":"resources/genome_annotation.gff3","start":143516,"strand":"+","type":"gene"},"OPG166":{"end":144577,"seqid":"resources/genome_annotation.gff3","start":144398,"strand":"+","type":"gene"},"OPG167":{"end":145407,"seqid":"resources/genome_annotation.gff3","start":144574,"strand":"-","type":"gene"},"OPG170":{"end":146778,"seqid":"resources/genome_annotation.gff3","start":146113,"strand":"-","type":"gene"},"OPG171":{"end":147389,"seqid":"resources/genome_annotation.gff3","start":146988,"strand":"+","type":"gene"},"OPG172":{"end":148017,"seqid":"resources/genome_annotation.gff3","start":147427,"strand":"+","type":"gene"},"OPG173":{"end":148261,"seqid":"resources/genome_annotation.gff3","start":148037,"strand":"+","type":"gene"},"OPG174":{"end":149395,"seqid":"resources/genome_annotation.gff3","start":148355,"strand":"-","type":"gene"},"OPG175":{"end":149819,"seqid":"resources/genome_annotation.gff3","start":149442,"strand":"+","type":"gene"},"OPG176":{"end":150531,"seqid":"resources/genome_annotation.gff3","start":149809,"strand":"+","type":"gene"},"OPG178":{"end":152123,"seqid":"resources/genome_annotation.gff3","start":151509,"strand":"+","type":"gene"},"OPG180":{"end":154371,"seqid":"resources/genome_annotation.gff3","start":152692,"strand":"+","type":"gene"},"OPG181":{"end":155416,"seqid":"resources/genome_annotation.gff3","start":154412,"strand":"+","type":"gene"},"OPG185":{"end":159858,"seqid":"resources/genome_annotation.gff3","start":158917,"strand":"+","type":"gene"},"OPG187":{"end":161533,"seqid":"resources/genome_annotation.gff3","start":160622,"strand":"+","type":"gene"},"OPG188":{"end":163107,"seqid":"resources/genome_annotation.gff3","start":161596,"strand":"+","type":"gene"},"OPG189":{"end":165018,"seqid":"resources/genome_annotation.gff3","start":163333,"strand":"+","type":"gene"},"OPG190":{"end":166075,"seqid":"resources/genome_annotation.gff3","start":165122,"strand":"+","type":"gene"},"OPG191":{"end":166667,"seqid":"resources/genome_annotation.gff3","start":166161,"strand":"+","type":"gene"},"OPG192":{"end":167279,"seqid":"resources/genome_annotation.gff3","start":166731,"strand":"+","type":"gene"},"OPG193":{"end":168137,"seqid":"resources/genome_annotation.gff3","start":167334,"strand":"+","type":"gene"},"OPG195":{"end":168895,"seqid":"resources/genome_annotation.gff3","start":168230,"strand":"+","type":"gene"},"OPG197":{"end":169972,"seqid":"resources/genome_annotation.gff3","start":169670,"strand":"+","type":"gene"},"OPG198":{"end":170886,"seqid":"resources/genome_annotation.gff3","start":170038,"strand":"+","type":"gene"},"OPG199":{"end":172022,"seqid":"resources/genome_annotation.gff3","start":170988,"strand":"+","type":"gene"},"OPG200":{"end":172599,"seqid":"resources/genome_annotation.gff3","start":172150,"strand":"+","type":"gene"},"OPG204":{"end":175587,"seqid":"resources/genome_annotation.gff3","start":174532,"strand":"+","type":"gene"},"OPG205":{"end":178019,"seqid":"resources/genome_annotation.gff3","start":175656,"strand":"+","type":"gene"},"OPG208":{"end":180339,"seqid":"resources/genome_annotation.gff3","start":179266,"strand":"+","type":"gene"},"OPG209":{"end":181090,"seqid":"resources/genome_annotation.gff3","start":180518,"strand":"+","type":"gene"},"OPG210":{"end":186998,"seqid":"resources/genome_annotation.gff3","start":181356,"strand":"+","type":"gene"},"nuc":{"end":197209,"start":1,"strand":"+","type":"source"}},"colorings":[{"key":"clade_membership","title":"Clade","type":"categorical","scale":[["IIb","#DEA73C"]]},{"key":"gt","title":"Genotype","type":"categorical"},{"key":"outbreak","title":"Outbreak","type":"categorical","scale":[["hMPXV-1","#4C90C0"]]},{"key":"lineage","title":"Lineage","type":"categorical","scale":[["A","#5E1D9D"],["A.1","#4D22AE"],["A.1.1","#4531BC"],["B.1","#4041C7"],["B.1.1","#3F53CD"],["B.1.2","#4064CF"],["B.1.3","#4375CD"],["C.1","#4784C8"],["B.1.4","#4C91BF"],["B.1.5","#539CB4"],["B.1.6","#5AA5A7"],["B.1.7","#63AC9A"],["B.1.8","#6CB28C"],["B.1.9","#77B67E"],["B.1.10","#82BA71"],["B.1.11","#8FBC66"],["B.1.12","#9CBE5B"],["B.1.13","#A9BD53"],["B.1.14","#B5BD4C"],["B.1.15","#C1BA46"],["B.1.16","#CDB642"],["B.1.17","#D6B03F"],["B.1.18","#DEA73B"],["B.1.19","#E39B39"],["B.1.20","#E68D36"],["A.2","#E67C33"],["A.2.1","#E5692F"],["A.2.2","#E1532B"],["A.2.3","#DE3E27"],["A.3","#DB2823"]]},{"key":"date","title":"Collection Date","type":"categorical"},{"key":"host","title":"Host","type":"categorical"},{"key":"strain","title":"Strain name","type":"categorical"},{"key":"strain_display","title":"Pretty strain name","type":"categorical"},{"key":"region","title":"Region","type":"categorical","scale":[["Asia","#447CCD"],["Oceania","#5EA9A1"],["Africa","#8ABB6A"],["Europe","#BEBB48"],["South America","#E29E39"],["North America","#E2562B"]]},{"key":"country","title":"Country","type":"categorical","scale":[["Israel","#5E1D9D"],["Singapore","#4E21AD"],["Vietnam","#462EB9"],["Taiwan","#403CC5"],["South Korea","#3F4CCB"],["Japan","#3E5DD0"],["Australia","#416CCE"],["Benin","#447BCD"],["Nigeria","#4887C6"],["South Africa","#4D93BE"],["Portugal","#539CB3"],["Ireland","#5AA5A8"],["Spain","#62AB9C"],["United Kingdom","#6AB18F"],["France","#74B582"],["Belgium","#7EB876"],["Netherlands","#89BB6B"],["Switzerland","#94BD61"],["Germany","#A0BE59"],["Italy","#ABBD51"],["Slovenia","#B7BD4B"],["Sweden","#C2BA46"],["Austria","#CCB742"],["Czech Republic","#D5B13F"],["Slovakia","#DDAA3C"],["Romania","#E19F3A"],["Finland","#E69537"],["Brazil","#E68534"],["Peru","#E67631"],["Colombia","#E4632E"],["Mexico","#E14F2A"],["USA","#DE3C26"],["Canada","#DB2823"]]}],"filters":["clade_membership","lineage","country","host","institution","region"],"panels":["tree","entropy"],"extensions":{"nextclade":{"clade_node_attrs":[{"name":"outbreak","displayName":"Outbreak","description":""},{"name":"lineage","displayName":"Lineage","description":""}]}}},"tree":{"name":"NODE_0000001","node_attrs":{"div":0,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{},"labels":{"clade":"A"}},"children":[{"name":"NC_063383","node_attrs":{"div":0,"accession":"NC_063383","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Senkevich,T.G.,Yutin,N.,Wolf,Y.I.,Koonin,E.V.,Moss,B.,Zmasek,C.M.,Knipe,D.M.,Pellett,P.E.,Scheuermann,R.H.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Senkevich,T.G.,Yutin,N.,Wolf,Y.I.,Koonin,E.V.,Moss,B.,Zmasek,C.M.,Knipe,D.M.,Pellett,P.E.,Scheuermann,R.H."},"strain":{"value":"MPXV-M5312_HM12_Rivers"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/NC_063383/2018-08-XX"},"country":{"value":"Nigeria"},"institution":{"value":"National Center for Biotechnology Information, NIH"},"date":{"value":"2018-08-XX"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000000","node_attrs":{"div":0,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{}},"children":[{"name":"NC_063383.1","node_attrs":{"div":0,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000002","node_attrs":{"div":1,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["T28175C"]}},"children":[{"name":"OP535333","node_attrs":{"div":4,"accession":"OP535333","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"strain":{"value":"MPXV_Nigeria_2018_5231"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP535333/2018-01-XX"},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"date":{"value":"2018-01-XX"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["T6635G","T6638G","T6660G","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-"]}}},{"name":"NODE_0000003","node_attrs":{"div":5,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["T608-","T609-","A18769G","A81977G","A100261G","A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","T154408C","A196616-","A196617-"],"OPG118":["K606E"]},"labels":{"aa":"OPG118: K606E"}},"children":[{"name":"MK783031","node_attrs":{"div":9,"accession":"MK783031","author":{"author":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J.","value":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J."},"strain":{"value":"MK783031"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/MK783031/2017-11-09"},"country":{"value":"Nigeria"},"institution":{"value":"NCEZID/DHCPP/PRB, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2017-11-09"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["C5157T","G7764A","G9782A","G109736A","C133161T","G192053A"],"OPG015":["D334N"],"OPG015_dup":["D334N"],"OPG019":["R62K"],"OPG021":["A66T"]},"labels":{"aa":"OPG015: D334N; OPG015_dup: D334N; OPG019: R62K; OPG021: A66T"}}},{"name":"KJ642617","node_attrs":{"div":38,"accession":"KJ642617","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"strain":{"value":"KJ642617"},"region":{"value":"Africa"},"clade_membership":{"value":"outgroup"},"strain_display":{"value":"Nigeria/KJ642617/1971-XX-XX"},"country":{"value":"Nigeria"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"date":{"value":"1971-XX-XX"}},"branch_attrs":{"mutations":{"nuc":["T607-","A3450G","A8893C","G13625A","A18312G","T19367C","A32210-","C32211-","G32212-","T33143C","A38067G","A46895G","G48138A","A48527C","A53207C","A66580G","T80986C","C92516T","G98489-","C98727T","T100562C","C105126T","T119718C","A128076G","A129762G","T133145C","T136555C","A137627G","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","A141300G","T141364C","A142450C","C146687T","G149744A","G149878A","A158170-","G160174T","C160852T","A160867G","T166656-","T166657-","T167656G","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","A171675G","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","A178423G","A181253-","T187080-","T193760C","A196615-"],"OPG025":["T548M"],"OPG049":["R314-"],"OPG056":["V323A"],"OPG071":["L411W"],"OPG084":["Q620R"],"OPG104":["T12A"],"OPG150":["N100D"],"OPG151":["D280G"],"OPG153":["M14T"],"OPG159":["N124-","Y125-","N126-"],"OPG161":["K67E","V88A"],"OPG170":["G31D"],"OPG176":["D24N"],"OPG191":["F166-"],"OPG193":["I108R"],"OPG197":["T34-","D35-"],"OPG199":["K230E"]},"labels":{"aa":"OPG025: T548M; OPG049: R314-; OPG056: V323A; OPG071: L411W; OPG084: Q620R; OPG104: T12A; OPG150: N100D; OPG151: D280G; OPG153: M14T; OPG159: N124-, Y125-, N126-; OPG161: K67E, V88A; OPG170: G31D; OPG176: D24N; OPG191: F166-; OPG193: I108R; OPG197: T34-, D35-; OPG199: K230E","clade":"outgroup"}}},{"name":"OP535319","node_attrs":{"div":27,"accession":"OP535319","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"strain":{"value":"MPXV_Nigeria_2017_5205"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP535319/2017-12-XX"},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"date":{"value":"2017-12-XX"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["C8634T","C14067T","C33332T","C67253T","C110326T","C117099T","C122737T","G125303A","G129583A","A136552-","T136553-","C136554-","G157078C","A157083C","T157101C","T157109C","T157112C","G157119C","C157126A","G157128A","G157129A","G157197A","G157200A","C157296T","C157729A","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","T178048-"],"OPG025":["D401N"],"OPG050":["R26Q"],"OPG085":["D427N"],"OPG129":["E227K"],"OPG136":["R830Q"],"OPG145":["D453N"],"OPG153":["D385-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG025: D401N; OPG050: R26Q; OPG085: D427N; OPG129: E227K; OPG136: R830Q; OPG145: D453N; OPG153: D385-; OPG197: T34-, D35-"}}},{"name":"NODE_0000004","node_attrs":{"div":8,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["G51559A","C60923T","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","G179884A"],"OPG080":["E366K"],"OPG197":["T34-","D35-"],"OPG208":["E207K"]},"labels":{"aa":"OPG080: E366K; OPG197: T34-, D35-; OPG208: E207K"}},"children":[{"name":"MT903337","node_attrs":{"div":10,"accession":"MT903337","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"strain":{"value":"MPXV-M2940_FCT"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/MT903337/2018-XX-XX"},"country":{"value":"Nigeria"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2018-XX-XX"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["G172784A","T181577C"]}}},{"name":"OP535326","node_attrs":{"div":14,"accession":"OP535326","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"strain":{"value":"MPXV_Nigeria_2018_5315"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP535326/2018-06-XX"},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"date":{"value":"2018-06-XX"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["C23000T","G29826A","C109667T","A136552-","T136553-","C136554-","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","G147459A","G155644A","-169769A","-169770C","-169771A","-169772G","-169773A","-169774T","G177009A","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG038":["G54S"],"OPG047":["R457C"],"OPG153":["D385-"],"OPG197":["-34T","-35D"],"OPG205":["E452K"]},"labels":{"aa":"OPG038: G54S; OPG047: R457C; OPG153: D385-; OPG197: -34T, -35D; OPG205: E452K"}}},{"name":"OP535312","node_attrs":{"div":12,"accession":"OP535312","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"strain":{"value":"MPXV_Nigeria_2018_5222"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP535312/2018-02-XX"},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"date":{"value":"2018-02-XX"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["T607-","C101683T","C127245T","A174524-","G174525-","A174526-","G178814A","G178988A","A196615-"],"OPG149":["S17L"]},"labels":{"aa":"OPG149: S17L"}}}]},{"name":"NODE_0000010","node_attrs":{"div":7,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["T607-","G37209A","G48180A","A196615-"],"OPG056":["S609F"]},"labels":{"aa":"OPG056: S609F"}},"children":[{"name":"OP535341","node_attrs":{"div":12,"accession":"OP535341","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"strain":{"value":"MPXV_Nigeria_2017_2886"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP535341/2017-10-XX"},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"date":{"value":"2017-10-XX"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["G3477A","C22179T","C98046T","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","C172965T","G174056A","C193733T"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"NODE_0000011","node_attrs":{"div":11,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["T606-","C8385T","G43118A","C113841T","A136552-","T136553-","C136554-","C146607T","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T"],"OPG133":["G619E"],"OPG153":["D385-"],"OPG170":["E58K"]},"labels":{"aa":"OPG133: G619E; OPG153: D385-; OPG170: E58K"}},"children":[{"name":"OP535327","node_attrs":{"div":12,"accession":"OP535327","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"strain":{"value":"MPXV_Nigeria_2018_5307"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP535327/2018-03-XX"},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"date":{"value":"2018-03-XX"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["T6706G","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A196614-"]}}},{"name":"NODE_0000012","node_attrs":{"div":12,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["G29889A","T76087-","A89106-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-"],"OPG047":["P436S"]},"labels":{"aa":"OPG047: P436S"}},"children":[{"name":"NODE_0000013","node_attrs":{"div":15,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["C40251T","C63801T","T121121-","G162243A","-196615A","-196616A"],"OPG058":["D62N"],"OPG083":["E306K"]},"labels":{"aa":"OPG058: D62N; OPG083: E306K"}},"children":[{"name":"OP612684","node_attrs":{"div":18,"accession":"OP612684","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"strain":{"value":"MPXV/046/19"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP612684/2019-05-XX"},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"date":{"value":"2019-05-XX"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["C92830T","A136543-","T136544-","C136545-","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","-173288A","-173289T","G180656A","G186423A","-196617A"],"OPG113":["S367F"],"OPG153":["D382-","D383-","D384-"],"OPG209":["D47N"],"OPG210":["E1690K"]},"labels":{"aa":"OPG113: S367F; OPG153: D382-, D383-, D384-; OPG209: D47N; OPG210: E1690K"}}},{"name":"OP612680","node_attrs":{"div":17,"accession":"OP612680","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"strain":{"value":"MPXV/021/19"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP612680/2019-04-01"},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"date":{"value":"2019-04-01"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["C63264T","-89106A","T104748C","T133098-","T133099-","T133100-","T133101-","T133102-","T187080-"],"OPG123":["D108G"]},"labels":{"aa":"OPG123: D108G"}}}]},{"name":"NODE_0000014","node_attrs":{"div":15,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["-606T","-607T","-608T","-609T","C28164T","C87027T","G121454A"],"OPG044":["S25F"]},"labels":{"aa":"OPG044: S25F"}},"children":[{"name":"OP612678","node_attrs":{"div":18,"accession":"OP612678","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"strain":{"value":"MPXV/017/19"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP612678/2019-03-14"},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"date":{"value":"2019-03-14"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["G46685A","G144659A","G165688A","T187080-","A196614-"],"OPG167":["S250F"]},"labels":{"aa":"OPG167: S250F"}}},{"name":"NODE_0000015","node_attrs":{"div":17,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["G3531A","-76087T","T151621G","T179068A","-196615A","-196616A","-196617A"],"OPG178":["F38C"]},"labels":{"aa":"OPG178: F38C"}},"children":[{"name":"OP612675","node_attrs":{"div":18,"accession":"OP612675","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"strain":{"value":"MPXV/007/19"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP612675/2019-01-30"},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"date":{"value":"2019-01-30"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["T4676C","-89106A","-136552A","-136553T","-136554C","C193679T"]}}},{"name":"OP612676","node_attrs":{"div":17,"accession":"OP612676","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"strain":{"value":"MPXV/013/19"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP612676/2019-02-20"},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"date":{"value":"2019-02-20"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["A19360-","A23252-","T133100-","T133101-","T133102-","A138474-","A156769-","T163332-","A173514-","A173515-","G173516-","A173517-","A173518-","G173519-","A173520-","C173521-","G173522-","A173523-","G173524-","G173525-","A173526-","C173527-","G173528-","G173529-","A173530-","G173531-","A173532-","C173533-","G173534-","G173535-","T173536-","A173537-","G173538-","A173539-","A173540-","T173541-","A173542-","A173543-","T179072A"]}}}]}]}]}]}]},{"name":"NODE_0000016","node_attrs":{"div":6,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["G154015A"],"OPG180":["D442N"]},"labels":{"aa":"OPG180: D442N"}},"children":[{"name":"MK783032","node_attrs":{"div":14,"accession":"MK783032","author":{"author":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J.","value":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J."},"strain":{"value":"MK783032"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/MK783032/2017-11-XX"},"country":{"value":"Nigeria"},"institution":{"value":"NCEZID/DHCPP/PRB, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2017-11-XX"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["-608T","C10430T","C18699T","G26002A","C134814T","C143669T","G180039A","G180827A","G189317A","-196616A"],"OPG005":["R40K"],"OPG031":["D44N"],"OPG042":["R366C"],"OPG165":["L52F"],"OPG208":["M258I"],"OPG209":["E104K"]},"labels":{"aa":"OPG005: R40K; OPG031: D44N; OPG042: R366C; OPG165: L52F; OPG208: M258I; OPG209: E104K"}}},{"name":"NODE_0000017","node_attrs":{"div":21,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-","C13298T","C18792T","C30636T","C34472T","C34578T","G80099A","G93387A","G114659A","G124031A","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","C148529-","A148530-","T148531-","A148532-","T148533-","C148534-","A148535-","G149265A","C149872T","C161953T","C165782T","G168205A","C177720T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A196614-","A196615-"],"OPG031":["D13N"],"OPG047":["D187N"],"OPG053":["G38E"],"OPG113":["E553K"],"OPG145":["D29N"],"OPG153":["D383-","D384-","D385-"],"OPG174":["S44L","D288-","M289-"],"OPG176":["Q22*"],"OPG188":["H120Y"],"OPG190":["P221S"],"OPG205":["R689C"]},"labels":{"aa":"OPG031: D13N; OPG047: D187N; OPG053: G38E; OPG113: E553K; OPG145: D29N; OPG153: D383-, D384-, D385-; OPG174: S44L, D288-, M289-; OPG176: Q22*; OPG188: H120Y; OPG190: P221S; OPG205: R689C","clade":"A.2"}},"children":[{"name":"ON675438","node_attrs":{"div":43,"accession":"ON675438","author":{"author":"Gigante,C.M.,Griffin-Thomas,L.A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Crain,J.,Li,Y.","value":"Gigante,C.M.,Griffin-Thomas,L.A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Crain,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_VA001"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/ON675438/2022-05-XX"},"country":{"value":"USA"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2022-05-XX"},"lineage":{"value":"A.2"}},"branch_attrs":{"mutations":{"nuc":["-606T","-607T","G11332A","G12099A","C13648T","C15105T","C16227T","C29887T","C42101T","G64216A","G75614A","C117119T","C128534T","G130454A","C134442T","C142918T","G144446A","C156429T","C164832T","C168532T","G174610A","A175231-","T175232-","C175233-","G175234-","T175235-","A175236-","G175237-","T175238-","A175239-","T175240-","C175241-","A175242-","A175243-","G175244-","A175245-","T175246-","G175247-","T175248-","A175249-","A175250-","A175251-","A175252-","T175253-","A175254-","C175255-","T175256-","T175257-","A175258-","C175259-","G175260-","G175261-","T175262-","T175263-","A175264-","T175265-","A175266-","C175267-","C175268-","G175269-","T175270-","C175271-","A175272-","C175273-","A175274-","A175275-","G175276-","A175277-","C175278-","C175279-","A175280-","C175281-","A175282-","G175283-","G175284-","T175285-","T175286-","T175287-","A175288-","A175289-","A175290-","C175291-","T175292-","A175293-","A175294-","T175295-","A175296-","C175297-","T175298-","A175299-","G175300-","A175301-","T175302-","C175303-","C175304-","G175305-","A175306-","A175307-","A175308-","A175309-","T175310-","C175311-","A175312-","A175313-","C175314-","G175315-","T175316-","A175317-","A175318-","C175319-","G175320-","A175321-","T175322-","A175323-","G175324-","G175325-","A175326-","G175327-","A175328-","A175329-","C175330-","C175331-","T175332-","G175333-","C175334-","C175335-","A175336-","A175337-","T175338-","A175339-","T175340-","A175341-","A175342-","C175343-","A175344-","T175345-","G175346-","C175347-","A175348-","G175349-","T175350-","G175351-","C175352-","T175353-","G175354-","T175355-","G175356-","T175357-","C175358-","A175359-","A175360-","C175361-","G175362-","T175363-","C175364-","A175365-","T175366-","T175367-","A175368-","T175369-","T175370-","T175371-","G175372-","T175373-","C175374-","G175375-","A175376-","C175377-","G175378-","A175379-","T175380-","G175381-","T175382-","A175383-","C175384-","T175385-","G175386-","A175387-","T175388-","T175389-","G175390-","A175391-","A175392-","T175393-","G175394-","G175395-","G175396-","A175397-","A175398-","A175399-","A175400-","T175401-","C175402-","C175403-","A175404-","T175405-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A179628G","C179853T","G188544A","-196614A"],"OPG023":["R268*"],"OPG025":["D55N","M540I"],"OPG027":["D51N"],"OPG062":["S52L"],"OPG096":["D10N"],"OPG151":["E511K"],"OPG166":["D17N"],"OPG204":["E27K","I234-","V235-","V236-","S237-","R238-","C239-","K240-","I241-","L242-","T243-","V244-","I245-","P246-","S247-","Q248-","D249-","H250-","R251-","F252-","K253-","L254-","I255-","L256-","D257-","P258-","K259-","I260-","N261-","V262-","T263-","I264-","G265-","E266-","P267-","A268-","N269-","I270-","T271-","C272-","S273-","A274-","V275-","S276-","T277-","S278-","L279-","F280-","V281-","D282-","D283-","V284-","L285-","I286-","E287-","W288-","E289-","N290-","P291-","S292-"]},"labels":{"aa":"OPG023: R268*; OPG025: D55N, M540I; OPG027: D51N; OPG062: S52L; OPG096: D10N; OPG151: E511K; OPG166: D17N; OPG204: E27K, I234-, V235-, V236-, S237-, R238-, C239-, K240-, I241-, L242-, T243-, V244-, I245-, P246-, S247-, Q248-, D249-, H250-, R251-, F252-, K253-, L254-, I255-, L256-, D257-, P258-, K259-, I260-, N261-, V262-, T263-, I264-, G265-, E266-, P267-, A268-, N269-, I270-, T271-, C272-, S273-, A274-, V275-, S276-, T277-, S278-, L279-, F280-, V281-, D282-, D283-, V284-, L285-, I286-, E287-, W288-, E289-, N290-, P291-, S292-"}}},{"name":"OP612689","node_attrs":{"div":22,"accession":"OP612689","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"strain":{"value":"MPXV/111/19"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP612689/2019-12-17"},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"date":{"value":"2019-12-17"},"lineage":{"value":"A.2"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G144876A","G173355-","A173356-","G173357-","G173358-","T173359-","A173360-","C173361-","G173362-","G173363-","G173364-","A173365-","T173366-","A173367-","G173368-","A173369-","A173370-","T173371-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG167":["P178S"]},"labels":{"aa":"OPG167: P178S"}}},{"name":"NODE_0000018","node_attrs":{"div":36,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.3"}},"branch_attrs":{"mutations":{"nuc":["G2752A","G39173A","C57284T","G61844A","C74226T","G118739A","C146223T","G148427A","G150800A","G168365A","G170317A","G172527A","C175759T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G189417A","C189474T","C194458T"],"OPG075":["R72K"],"OPG170":["D186N"],"OPG195":["E46K"],"OPG198":["D94N"],"OPG205":["A35V"]},"labels":{"aa":"OPG075: R72K; OPG170: D186N; OPG195: E46K; OPG198: D94N; OPG205: A35V","clade":"A.2.3"}},"children":[{"name":"ON676707","node_attrs":{"div":39,"accession":"ON676707","author":{"author":"Gigante,C.M.,Stringer,J.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Schulte,J.,Li,Y.","value":"Gigante,C.M.,Stringer,J.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Schulte,J.,Li,Y."},"strain":{"value":"MPXV_USA_2021_TX"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/ON676707/2021-07-XX"},"country":{"value":"USA"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2021-07-XX"},"lineage":{"value":"A.2.3"}},"branch_attrs":{"mutations":{"nuc":["-606T","C100640T","G142636A","C186104T","-196614A"]}}},{"name":"OP555515","node_attrs":{"div":49,"accession":"OP555515","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0428/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555515/2022-08-01"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-01"},"lineage":{"value":"A.2.3"}},"branch_attrs":{"mutations":{"nuc":["C30669T","C45028T","G49377A","G95355A","C121320T","G136132A","-136546A","-136547T","-136548C","G142265A","C159143T","C162264T","C170573T","C180686T","C181216T","G188229A"],"OPG047":["E176K"],"OPG064":["E291K"],"OPG068":["D393N"],"OPG139":["A17T"],"OPG153":["-383D"],"OPG163":["D22N"],"OPG185":["S76F"],"OPG198":["S179L"],"OPG209":["Q57*"]},"labels":{"aa":"OPG047: E176K; OPG064: E291K; OPG068: D393N; OPG139: A17T; OPG153: -383D; OPG163: D22N; OPG185: S76F; OPG198: S179L; OPG209: Q57*"}}}]},{"name":"NODE_0000019","node_attrs":{"div":41,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.2"}},"branch_attrs":{"mutations":{"nuc":["G11948A","C14790T","G21991A","G23118A","G38923A","G39515A","G56546A","G57786A","G93312A","C103019T","C112470T","C124129T","C127906T","G135303A","G145902A","C149365T","G155611A","G158424A","G162640A","G186984A"],"OPG023":["S318F"],"OPG025":["D160N"],"OPG037":["S148L"],"OPG056":["R38C"],"OPG113":["V528I"],"OPG122":["H198Y"],"OPG132":["M357I"],"OPG150":["S43L"],"OPG153":["D382-"],"OPG174":["G11R"],"OPG188":["G349S"],"OPG210":["D1877N"]},"labels":{"aa":"OPG023: S318F; OPG025: D160N; OPG037: S148L; OPG056: R38C; OPG113: V528I; OPG122: H198Y; OPG132: M357I; OPG150: S43L; OPG153: D382-; OPG174: G11R; OPG188: G349S; OPG210: D1877N","clade":"A.2.2"}},"children":[{"name":"OP422631","node_attrs":{"div":45,"accession":"OP422631","author":{"author":"Martin,F.,Anges,Y.,Benjamin,H.,Amadou,S.A.,Ousmane,F.","value":"Martin,F.,Anges,Y.,Benjamin,H.,Amadou,S.A.,Ousmane,F."},"strain":{"value":"MPXV-SEN0021"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Benin/OP422631/2022-06-XX"},"country":{"value":"Benin"},"institution":{"value":"Institut Pasteur de Dakar, Virology Department"},"date":{"value":"2022-06-XX"},"lineage":{"value":"A.2.2"}},"branch_attrs":{"mutations":{"nuc":["T4619C","C4623-","T4624-","T4625-","T4626-","T4627-","T4628-","C4629-","A4630-","T4631-","A4632-","A4633-","T4634-","T4635-","A4636-","G4637-","A4638-","G4639-","A4640-","A4641-","A4642-","A4643-","A4644-","G4645-","A4646-","T4647-","C4648-","A4649-","A4650-","G4651-","G4652-","T4653-","A4654-","T4655-","A4656-","A4657-","A4658-","A4659-","A4660-","T4661-","T4662-","A4663-","G4664-","A4665-","A4666-","G4667-","T4668-","G4669-","T4670-","T4671-","A4672-","G4673-","A4674-","C4675-","T4676-","A4677-","T4678-","A4679-","A4680-","C32643T","-136546A","-136547T","-136548C","-136549A","-136550T","-136551C","-136552A","-136553T","-136554C","A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","-148529C","-148530A","-148531T","-148532A","-148533T","-148534C","-148535A","C156429T","G172501A","T196689-"],"OPG049":["R170K"],"OPG153":["-382D","-383D","-384D","-385D"],"OPG174":["-288D","-289M"],"OPG200":["E118K"]},"labels":{"aa":"OPG049: R170K; OPG153: -382D, -383D, -384D, -385D; OPG174: -288D, -289M; OPG200: E118K"}}},{"name":"OP450997","node_attrs":{"div":48,"accession":"OP450997","author":{"author":"Gigante,C.M.,Xia,D.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y.","value":"Gigante,C.M.,Xia,D.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y."},"strain":{"value":"MPXV_USA_2022_PA0016"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP450997/2022-07-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-07-XX"},"lineage":{"value":"A.2.2"}},"branch_attrs":{"mutations":{"nuc":["G451A","G20576A","C20581T","G67351A","G78259A","G94479A","C133402T","A136543-","T136544-","C136545-","C176148T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C196759T"],"OPG036":["E162K"],"OPG085":["S394F"],"OPG205":["H165Y"]},"labels":{"aa":"OPG036: E162K; OPG085: S394F; OPG205: H165Y"}}},{"name":"NODE_0000020","node_attrs":{"div":46,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.2"}},"branch_attrs":{"mutations":{"nuc":["C13686T","C21861T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G151112A","G174721A","C188491T"],"OPG025":["E528K"],"OPG037":["M191I"],"OPG204":["A64T"]},"labels":{"aa":"OPG025: E528K; OPG037: M191I; OPG204: A64T"}},"children":[{"name":"OP331336","node_attrs":{"div":50,"accession":"OP331336","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPXV_UK_2022_9000166"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP331336/2022-06-29"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-29"},"lineage":{"value":"A.2.2"}},"branch_attrs":{"mutations":{"nuc":["C27826T","G59282A","C65743A","G85356A","A136543-","T136544-","C136545-"],"OPG043":["E44K"],"OPG084":["P341H"],"OPG106":["S48F"]},"labels":{"aa":"OPG043: E44K; OPG084: P341H; OPG106: S48F"}}},{"name":"OR113690","node_attrs":{"div":56,"accession":"OR113690","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"strain":{"value":"hMPXV/Austria/MUW1607960/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Austria/OR113690/2023-04-05"},"country":{"value":"Austria"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"date":{"value":"2023-04-05"},"lineage":{"value":"A.2.2"}},"branch_attrs":{"mutations":{"nuc":["C18102T","C52429T","C86957T","G97318A","C121394T","G129982A","-136546A","-136547T","-136548C","-136549A","-136552A","-136553T","-136554C","G146714A","C148895A","G165892A","G175471A"],"OPG031":["D243N"],"OPG108":["D35N"],"OPG117":["D424N"],"OPG170":["A22V"],"OPG174":["M167I"],"OPG204":["E314K"]},"labels":{"aa":"OPG031: D243N; OPG108: D35N; OPG117: D424N; OPG170: A22V; OPG174: M167I; OPG204: E314K"}}}]}]},{"name":"NODE_0000021","node_attrs":{"div":22,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2"}},"branch_attrs":{"mutations":{"nuc":["-606T","-607T","-608T","C25072T","A136543-","T136544-","C136545-"],"OPG040":["R136Q"],"OPG153":["D382-"]},"labels":{"aa":"OPG040: R136Q; OPG153: D382-"}},"children":[{"name":"OP612691","node_attrs":{"div":24,"accession":"OP612691","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"strain":{"value":"MPXV/191/20"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP612691/2020-01-XX"},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"date":{"value":"2020-01-XX"},"lineage":{"value":"A.2"}},"branch_attrs":{"mutations":{"nuc":["-609T","C90329T","C132520T","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG111":["S22L"]},"labels":{"aa":"OPG111: S22L"}}},{"name":"NODE_0000022","node_attrs":{"div":35,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["G36898A","G42183A","C42903T","G50346A","C54268T","C73616T","G79406A","G105746A","A140492C","C142498T","C157737T","C161152T","A169763-","C169764-","A169765-","G169766-","A169767-","T169768-","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","C179537T","-196614A","-196615A"],"OPG062":["M79I"],"OPG063":["M262I"],"OPG069":["D121N"],"OPG102":["D108N"],"OPG160":["S195A"],"OPG197":["T32-","D33-","T34-","D35-"],"OPG208":["S91L"]},"labels":{"aa":"OPG062: M79I; OPG063: M262I; OPG069: D121N; OPG102: D108N; OPG160: S195A; OPG197: T32-, D33-, T34-, D35-; OPG208: S91L","clade":"A.2.1"}},"children":[{"name":"NODE_0000023","node_attrs":{"div":36,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["T95936A"],"OPG116":["D192E"]},"labels":{"aa":"OPG116: D192E"}},"children":[{"name":"ON674051","node_attrs":{"div":38,"accession":"ON674051","author":{"author":"Gigante,C.M.,Lee,P.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y."},"strain":{"value":"MPXV_USA_2022_FL001"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/ON674051/2022-05-XX"},"country":{"value":"USA"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2022-05-XX"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["T608-","C112544T","G163540A"],"OPG132":["D333N"],"OPG189":["E70K"]},"labels":{"aa":"OPG132: D333N; OPG189: E70K"}}},{"name":"OR459776","node_attrs":{"div":44,"accession":"OR459776","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain":{"value":"MPXV-ROK-P003-2022"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"South Korea/OR459776/2022-11-15"},"country":{"value":"South Korea"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2022-11-15"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["-609T","A46522G","G52289A","G67261A","C72231T","C115379T","C135822T","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G181947A","G182189A","-196616A","-196617A"],"OPG071":["T717I"],"OPG085":["S424L"],"OPG210":["D198N"]},"labels":{"aa":"OPG071: T717I; OPG085: S424L; OPG210: D198N"}}}]},{"name":"NODE_0000024","node_attrs":{"div":36,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C184924T","-196616A","-196617A"],"OPG210":["S1190L"]},"labels":{"aa":"OPG210: S1190L"}},"children":[{"name":"OP936000","node_attrs":{"div":45,"accession":"OP936000","author":{"author":"Nguyen,D.T.,Le,H.M.,Huynh,H.T.T.,Tang,T.C.,Le,N.H.,Nguyen,H.H.,Nghiem,N.M.,Nguyen,H.T.T.,Vo,Q.T.,Vu,T.T.K.,Nguyen,T.T.,Phan,T.V.,Nguyen,T.L.N.,Le,T.M.,Vo,Q.M.,Dinh,M.N.H.,Nguyen,P.T.,Tran,P.T.L.,Tran,T.T.T.,Pham,T.T.N.,Nguyen,T.H.,Truong,L.T.T.,Nguyen,H.N.T.,Tran,T.T.,Le,K.T.T.,Lam,Y.M.,Thwaites,G.,Thwaites,L.,Nguyen,C.V.V.,Nguyen,A.T.,Le,T.V.","value":"Nguyen,D.T.,Le,H.M.,Huynh,H.T.T.,Tang,T.C.,Le,N.H.,Nguyen,H.H.,Nghiem,N.M.,Nguyen,H.T.T.,Vo,Q.T.,Vu,T.T.K.,Nguyen,T.T.,Phan,T.V.,Nguyen,T.L.N.,Le,T.M.,Vo,Q.M.,Dinh,M.N.H.,Nguyen,P.T.,Tran,P.T.L.,Tran,T.T.T.,Pham,T.T.N.,Nguyen,T.H.,Truong,L.T.T.,Nguyen,H.N.T.,Tran,T.T.,Le,K.T.T.,Lam,Y.M.,Thwaites,G.,Thwaites,L.,Nguyen,C.V.V.,Nguyen,A.T.,Le,T.V."},"strain":{"value":"Mpox-HCMC-M157"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"strain_display":{"value":"Vietnam/OP936000/2022-09-26"},"country":{"value":"Vietnam"},"institution":{"value":"EI group, Oxford University Clinica Research Unit"},"date":{"value":"2022-09-26"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["T647-","G648-","C32252T","G51559A","A86823T","G103706A","C152033T","T167015G","A167020T","A167021-","C167022-","G167029C","A187574C"]}}},{"name":"NODE_0000025","node_attrs":{"div":37,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["G43103A","A136540-","T136541-","C136542-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"],"OPG063":["P196S"],"OPG153":["D381-"]},"labels":{"aa":"OPG063: P196S; OPG153: D381-"}},"children":[{"name":"OR455100","node_attrs":{"div":43,"accession":"OR455100","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-081251/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR455100/2023-08-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-08-XX"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["-609T","C29438T","G58696A","G120906A","G147352A","G178102A","C187942T","A192392-","A192393-","A192394-","T192395-","G192396-","A192397-","G192398-","T192399-","T192400-","A192401-","A192402-","T192403-","A192404-","G192405-"],"OPG046":["V98I"],"OPG078":["S39L"],"OPG138":["S76F"],"OPG171":["R122K"]},"labels":{"aa":"OPG046: V98I; OPG078: S39L; OPG138: S76F; OPG171: R122K"}}},{"name":"NODE_0000026","node_attrs":{"div":39,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["G30868A","G102599A","-133098T","-133099T","-133100T","-169763A","-169764C","-169765A","-169766G","-169767A","-169768T","-169769A","-169770C","-169771A","-169772G","-169773A","-169774T"],"OPG122":["D58N"],"OPG197":["-32T","-33D","-34T","-35D"]},"labels":{"aa":"OPG122: D58N; OPG197: -32T, -33D, -34T, -35D"}},"children":[{"name":"OP331335","node_attrs":{"div":40,"accession":"OP331335","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPXV_UK_2022_9000155"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP331335/2022-06-03"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-03"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["T607-","T608-","-133101T","-133102T","-136540A","-136541T","-136542C","-136543A","-136544T","-136545C","-136546A","-136547T","-136548C","-136549A","-136550T","-136551C","-136552A","-136553T","-136554C","C164210T","-174531G","-174532A","-174533T","-174534G","-174535A","-174536A"],"OPG153":["-381D","-382D","-383D","-384D","-385D"],"OPG189":["S293L"]},"labels":{"aa":"OPG153: -381D, -382D, -383D, -384D, -385D; OPG189: S293L"}}},{"name":"OP605572","node_attrs":{"div":39,"accession":"OP605572","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain":{"value":"Slovenia-MPXV-30-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Slovenia/OP605572/2022-07-XX"},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-07-XX"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["C165-","A196625-","T196626-","T196627-"]}}}]}]}]}]}]}]}]},{"name":"NODE_0000057","node_attrs":{"div":6,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["A173314-","T173315-","A173316-","T173317-","C187428T"]}},"children":[{"name":"NODE_0000005","node_attrs":{"div":14,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["G56968A","G61844A","C84008T","G96841A","C100971T","C134078T","C151050T","G188889-"],"OPG074":["S53L"],"OPG117":["D265N"],"OPG120":["E260K"]},"labels":{"aa":"OPG074: S53L; OPG117: D265N; OPG120: E260K","clade":"A.3"}},"children":[{"name":"MG693723","node_attrs":{"div":27,"accession":"MG693723","author":{"author":"Faye,O.,Pratt,C.B.,Faye,M.,Fall,G.,Chitty,J.A.,Diagne,M.M.,Wiley,M.R.,Yinka-Ogunleye,A.F.,Aruna,S.,Etebu,E.N.,Aworabhi,N.,Ogoina,D.,Numbere,W.,Mba,N.,Palacios,G.,Sall,A.A.,Ihekweazu,C.,Diagne,M.,Palacios,G.F.,Sall,A.","value":"Faye,O.,Pratt,C.B.,Faye,M.,Fall,G.,Chitty,J.A.,Diagne,M.M.,Wiley,M.R.,Yinka-Ogunleye,A.F.,Aruna,S.,Etebu,E.N.,Aworabhi,N.,Ogoina,D.,Numbere,W.,Mba,N.,Palacios,G.,Sall,A.A.,Ihekweazu,C.,Diagne,M.,Palacios,G.F.,Sall,A."},"strain":{"value":"MPXV_Nig_2017_297957"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/MG693723/2017-XX-XX"},"country":{"value":"Nigeria"},"institution":{"value":"USAMRIID, Center for Genome Sciences"},"date":{"value":"2017-XX-XX"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["A8143-","G8144-","C8145-","A8146-","T8147-","A8148-","T8149-","T8150-","A8151-","A8152-","A8153-","G8154-","T8155-","A8156-","A8157-","A8158-","A8159-","T8160-","C8161-","T8162-","A8163-","G8164-","T8165-","T8166-","A8167-","C8168-","C8169-","T8170-","T8171-","G8172-","A8173-","A8174-","A8175-","A8176-","T8177-","G8178-","A8179-","A8180-","T8181-","A8182-","C8183-","A8184-","G8185-","T8186-","G8187-","G8188-","G8189-","T8190-","G8191-","G8192-","T8193-","T8194-","C8195-","C8196-","G8197-","T8198-","A8199-","T8200-","C8201-","A8202-","C8203-","C8204-","A8205-","G8206-","T8207-","A8208-","A8209-","G8210-","A8211-","A8212-","C8213-","A8214-","T8215-","A8216-","A8217-","T8218-","A8219-","G8220-","T8221-","C8222-","G8223-","A8224-","A8225-","T8226-","A8227-","C8228-","A8229-","G8230-","T8231-","A8232-","T8233-","C8234-","C8235-","G8236-","A8237-","T8238-","T8239-","G8240-","A8241-","G8242-","A8243-","T8244-","T8245-","T8246-","T8247-","G8248-","C8249-","A8250-","T8251-","A8252-","C8253-","A8254-","A8255-","T8256-","A8257-","C8258-","T8259-","A8260-","G8261-","T8262-","C8263-","T8264-","A8265-","G8266-","A8267-","A8268-","A8269-","G8270-","A8271-","A8272-","A8273-","T8274-","T8275-","T8276-","G8277-","T8278-","A8279-","A8280-","T8281-","C8282-","A8283-","T8284-","C8285-","C8286-","T8287-","C8288-","T8289-","G8290-","T8291-","G8292-","A8293-","C8294-","A8295-","G8296-","G8297-","A8298-","G8299-","T8300-","C8301-","C8302-","A8303-","T8304-","A8305-","T8306-","A8307-","T8308-","C8309-","T8310-","G8311-","T8312-","A8313-","T8314-","C8315-","A8316-","T8317-","C8318-","G8319-","T8320-","C8321-","T8322-","A8323-","G8324-","T8325-","T8326-","T8327-","T8328-","T8329-","A8330-","T8331-","C8332-","A8333-","G8334-","T8335-","G8336-","T8337-","C8338-","C8339-","T8340-","A8341-","T8342-","G8343-","C8344-","T8345-","A8346-","T8347-","A8348-","T8349-","T8350-","C8351-","C8352-","T8353-","G8354-","T8355-","T8356-","A8357-","T8358-","C8359-","A8360-","T8361-","C8362-","A8363-","T8364-","T8365-","A8366-","G8367-","T8368-","T8369-","A8370-","A8371-","T8372-","G8373-","A8374-","A8375-","A8376-","A8377-","T8378-","A8379-","A8380-","C8381-","T8382-","C8383-","T8384-","C8385-","G8386-","T8387-","G8388-","C8389-","T8390-","T8391-","C8392-","A8393-","G8394-","A8395-","A8396-","A8397-","A8398-","G8399-","T8400-","C8401-","A8402-","A8403-","A8404-","T8405-","A8406-","T8407-","T8408-","G8409-","T8410-","A8411-","T8412-","C8413-","C8414-","A8415-","T8416-","A8417-","C8418-","A8419-","T8420-","A8421-","T8422-","A8423-","T8424-","C8425-","T8426-","C8427-","C8428-","A8429-","A8430-","A8431-","A8432-","C8433-","T8434-","A8435-","T8436-","C8437-","A8438-","C8439-","T8440-","T8441-","A8442-","T8443-","A8444-","C8445-","G8446-","T8447-","T8448-","T8449-","A8450-","T8451-","C8452-","T8453-","T8454-","T8455-","A8456-","A8457-","C8458-","G8459-","A8460-","A8461-","C8462-","A8463-","T8464-","A8465-","T8466-","A8467-","C8468-","C8469-","T8470-","A8471-","G8472-","A8473-","T8474-","G8475-","G8476-","T8477-","T8478-","A8479-","T8480-","T8481-","T8482-","A8483-","C8484-","T8485-","A8486-","A8487-","C8488-","A8489-","G8490-","A8491-","C8492-","A8493-","T8494-","T8495-","T8496-","T8497-","T8498-","T8499-","C8500-","A8501-","A8502-","G8503-","A8504-","T8505-","C8506-","T8507-","A8508-","T8509-","T8510-","G8511-","A8512-","C8513-","A8514-","A8515-","T8516-","A8517-","A8518-","C8519-","T8520-","C8521-","C8522-","T8523-","A8524-","T8525-","A8526-","G8527-","T8528-","T8529-","T8530-","C8531-","C8532-","A8533-","C8534-","A8535-","T8536-","C8537-","A8538-","A8539-","C8540-","C8541-","A8542-","A8543-","G8544-","T8545-","A8546-","A8547-","T8548-","G8549-","A8550-","T8551-","C8552-","A8553-","T8554-","C8555-","T8556-","A8557-","T8558-","T8559-","G8560-","T8561-","T8562-","A8563-","T8564-","A8565-","T8566-","A8567-","A8568-","C8569-","A8570-","A8571-","T8572-","A8573-","A8574-","C8575-","A8576-","T8577-","A8578-","A8579-","C8580-","T8581-","C8582-","T8583-","T8584-","T8585-","T8586-","C8587-","C8588-","A8589-","T8590-","T8591-","T8592-","T8593-","T8594-","A8595-","T8596-","C8597-","A8598-","G8599-","T8600-","A8601-","T8602-","C8603-","T8604-","A8605-","T8606-","A8607-","T8608-","C8609-","A8610-","A8611-","C8612-","G8613-","T8614-","C8615-","G8616-","T8617-","T8618-","G8619-","T8620-","A8621-","G8622-","T8623-","G8624-","A8625-","A8626-","T8627-","A8628-","G8629-","T8630-","A8631-","G8632-","T8633-","C8634-","A8635-","T8636-","T8637-","G8638-","A8639-","T8640-","C8641-","T8642-","A8643-","T8644-","T8645-","A8646-","T8647-","A8648-","T8649-","G8650-","A8651-","A8652-","A8653-","C8654-","G8655-","G8656-","A8657-","T8658-","A8659-","T8660-","G8661-","T8662-","C8663-","T8664-","A8665-","G8666-","T8667-","T8668-","A8669-","A8670-","T8671-","A8672-","T8673-","T8674-","T8675-","T8676-","C8677-","T8678-","T8679-","T8680-","G8681-","A8682-","T8683-","T8684-","T8685-","A8686-","A8687-","A8688-","G8689-","T8690-","C8691-","T8692-","A8693-","T8694-","A8695-","G8696-","T8697-","C8698-","T8699-","T8700-","T8701-","A8702-","C8703-","A8704-","A8705-","A8706-","C8707-","A8708-","T8709-","A8710-","A8711-","T8712-","A8713-","T8714-","C8715-","C8716-","T8717-","T8718-","A8719-","T8720-","C8721-","C8722-","G8723-","A8724-","C8725-","T8726-","T8727-","T8728-","A8729-","T8730-","A8731-","T8732-","T8733-","T8734-","C8735-","C8736-","T8737-","G8738-","T8739-","A8740-","G8741-","G8742-","G8743-","T8744-","G8745-","G8746-","C8747-","A8748-","T8749-","A8750-","A8751-","T8752-","T8753-","T8754-","T8755-","A8756-","T8757-","T8758-","C8759-","T8760-","G8761-","C8762-","C8763-","T8764-","C8765-","C8766-","A8767-","C8768-","A8769-","A8770-","T8771-","C8772-","A8773-","G8774-","T8775-","G8776-","T8777-","T8778-","T8779-","C8780-","C8781-","A8782-","A8783-","A8784-","T8785-","A8786-","T8787-","A8788-","T8789-","T8790-","A8791-","C8792-","T8793-","A8794-","G8795-","A8796-","C8797-","A8798-","A8799-","T8800-","A8801-","T8802-","T8803-","C8804-","C8805-","A8806-","T8807-","A8808-","T8809-","A8810-","G8811-","T8812-","T8813-","A8814-","T8815-","T8816-","A8817-","G8818-","T8819-","T8820-","A8821-","A8822-","G8823-","G8824-","G8825-","A8826-","C8827-","C8828-","C8829-","A8830-","A8831-","T8832-","T8833-","A8834-","G8835-","A8836-","A8837-","C8838-","A8839-","C8840-","G8841-","T8842-","A8843-","C8844-","G8845-","C8846-","G8847-","C8848-","T8849-","T8850-","A8851-","T8852-","T8853-","C8854-","A8855-","T8856-","C8857-","A8858-","T8859-","T8860-","T8861-","G8862-","G8863-","A8864-","T8865-","C8866-","G8867-","T8868-","A8869-","T8870-","T8871-","T8872-","C8873-","A8874-","T8875-","A8876-","A8877-","A8878-","A8879-","G8880-","T8881-","T8882-","A8883-","T8884-","T8885-","A8886-","T8887-","G8888-","T8889-","T8890-","A8891-","T8892-","A8893-","G8894-","A8895-","T8896-","G8897-","T8898-","C8899-","A8900-","A8901-","C8902-","A8903-","C8904-","A8905-","T8906-","T8907-","C8908-","T8909-","A8910-","C8911-","A8912-","T8913-","T8914-","T8915-","T8916-","T8917-","T8918-","T8919-","A8920-","A8921-","T8922-","T8923-","G8924-","T8925-","C8926-","T8927-","A8928-","T8929-","A8930-","T8931-","A8932-","G8933-","T8934-","A8935-","T8936-","T8937-","T8938-","T8939-","T8940-","C8941-","T8942-","G8943-","A8944-","T8945-","A8946-","T8947-","T8948-","T8949-","T8950-","C8951-","T8952-","A8953-","T8954-","A8955-","A8956-","T8957-","A8958-","T8959-","C8960-","A8961-","G8962-","A8963-","A8964-","T8965-","T8966-","G8967-","T8968-","C8969-","T8970-","T8971-","C8972-","C8973-","A8974-","T8975-","A8976-","G8977-","G8978-","A8979-","A8980-","G8981-","T8982-","T8983-","G8984-","T8985-","A8986-","T8987-","A8988-","C8989-","T8990-","A8991-","T8992-","T8993-","C8994-","G8995-","G8996-","A8997-","A8998-","T8999-","C9000-","A9001-","G9002-","T9003-","T9004-","A9005-","C9006-","A9007-","T9008-","G9009-","T9010-","T9011-","T9012-","A9013-","A9014-","A9015-","T9016-","A9017-","A9018-","T9019-","T9020-","C9021-","T9022-","C9023-","T9024-","G9025-","A9026-","T9027-","G9028-","T9029-","C9030-","A9031-","T9032-","T9033-","C9034-","C9035-","T9036-","T9037-","A9038-","T9039-","A9040-","C9041-","A9042-","A9043-","T9044-","C9045-","A9046-","A9047-","A9048-","T9049-","T9050-","C9051-","A9052-","T9053-","T9054-","A9055-","T9056-","T9057-","A9058-","A9059-","A9060-","C9061-","A9062-","G9063-","T9064-","T9065-","T9066-","A9067-","A9068-","T9069-","A9070-","G9071-","T9072-","C9073-","T9074-","G9075-","T9076-","A9077-","G9078-","A9079-","C9080-","C9081-","T9082-","T9083-","T9084-","A9085-","T9086-","C9087-","G9088-","T9089-","C9090-","G9091-","T9092-","A9093-","C9094-","A9095-","T9096-","A9097-","T9098-","C9099-","C9100-","A9101-","T9102-","T9103-","G9104-","T9105-","C9106-","T9107-","T9108-","A9109-","T9110-","T9111-","A9112-","G9113-","T9114-","T9115-","A9116-","C9117-","G9118-","C9119-","T9120-","T9121-","A9122-","T9123-","T9124-","T9125-","T9126-","T9127-","A9128-","T9129-","G9130-","G9131-","G9132-","T9133-","T9134-","T9135-","T9136-","A9137-","C9138-","G9139-","T9140-","T9141-","G9142-","C9143-","T9144-","T9145-","T9146-","A9147-","T9148-","T9149-","A9150-","T9151-","A9152-","T9153-","T9154-","T9155-","T9156-","A9157-","T9158-","A9159-","A9160-","T9161-","A9162-","A9163-","T9164-","G9165-","A9166-","T9167-","T9168-","G9169-","T9170-","T9171-","T9172-","G9173-","A9174-","C9175-","A9176-","A9177-","T9178-","G9179-","T9180-","C9181-","G9182-","T9183-","A9184-","G9185-","T9186-","A9187-","T9188-","A9189-","G9190-","A9191-","T9192-","A9193-","T9194-","A9195-","T9196-","T9197-","A9198-","T9199-","T9200-","A9201-","G9202-","A9203-","G9204-","G9205-","A9206-","G9207-","G9208-","T9209-","A9210-","T9211-","A9212-","A9213-","T9214-","T9215-","A9216-","T9217-","A9218-","A9219-","A9220-","A9221-","A9222-","G9223-","T9224-","T9225-","T9226-","C9227-","T9228-","G9229-","A9230-","G9231-","T9232-","A9233-","C9234-","G9235-","A9236-","T9237-","G9238-","T9239-","T9240-","A9241-","T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","C9257-","A9258-","T9259-","T9260-","A9261-","A9262-","C9263-","A9264-","T9265-","C53702T","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","A166866-","C166867-","T166868-","G166869-","A166870-","T166871-","G166872-","A166873-","T166874-","A166875-","A166876-","T166877-","A166878-","A166879-","T166880-","G166881-","A166882-","A166883-","T166884-","T166885-","G166886-","G166887-","T166888-","G166889-","T166890-","T166891-","A166892-","A166893-","A166894-","T166895-","T166896-","T166897-","T166898-","A166899-","A166900-","A166901-","G166902-","A166903-","G166904-","T166905-","A166906-","C166907-","A166908-","C166909-","A166910-","A166911-","T166912-","T166913-","T166914-","C166915-","T166916-","A166917-","T166918-","T166919-","A166920-","T166921-","T166922-","A166923-","C166924-","A166925-","G166926-","A166927-","G166928-","T166929-","C166930-","A166931-","T166932-","G166933-","T166934-","G166935-","A166936-","C166937-","G166938-","T166939-","C166940-","G166941-","G166942-","A166943-","T166944-","T166945-","T166946-","G166947-","A166948-","T166949-","T166950-","C166951-","C166952-","A166953-","T166954-","A166955-","G166956-","A166957-","T166958-","A166959-","T166960-","A166961-","G166962-","A166963-","T166964-","G166965-","T166966-","T166967-","A166968-","T166969-","A166970-","A166971-","A166972-","C166973-","G166974-","A166975-","C166976-","T166977-","A166978-","T166979-","A166980-","A166981-","A166982-","A166983-","T166984-","T166985-","A166986-","T166987-","T166988-","G166989-","A166990-","T166991-","A166992-","T166993-","G166994-","T166995-","A166996-","T166997-","A166998-","C166999-","C168582A","C168584-","T168585-","C168586-","T168587-","G168588-","T168589-","A168590-","T168591-","T168592-","T168593-","C168594-","T168595-","G168596-","T168597-","A168598-","T168599-","A168600-","T168601-","T168602-","G168603-","T168604-","G168605-","A168606-","T168607-","C168608-","A168609-","A168610-","G168611-","A168612-","G168613-","G168614-","C168615-","G168616-","G168617-","G168618-","A168619-","G168620-","T168624G","A168626-","A168627-","A168628-","T168629-","T168630-","T168631-","G168632-","A168633-","G168634-","G168635-","A168636-","G168637-","T168638-","A168639-","T168640-","A168641-","C168642-","T168643-","C168644-","A168645-","A168646-","G168647-","A168648-","A168649-","T168650-","C168651-","A168652-","A168653-","G168654-","T168655-","G168656-","A168657-","T168658-","A168659-","T168660-","C168661-","A168662-","G168663-","T168664-","A168665-","T168666-","T168667-","A168668-","A168674-","A168675-","G168676-","T168677-","A168678-","T168679-","G168680-","A168681-","T168682-","T168683-","C168684-","A168685-","T168686-","C168687-","A168688-","T168689-","G168690-","T168691-","A168692-","T168693-","T168694-","G168695-","A168696-","T168697-","T168698-","A168699-","T168700-","G168704-","G168705-","T168706-","A168707-","T168708-","T168709-","A168710-","A168711-","T168712-","C168713-","A168714-","A168715-","A168716-","G168717-","T168718-","T168719-","T168720-","C168721-","A168722-","T168723-","G168724-","A168725-","A168726-","T168727-","T168731C","G168732A","A168734T","C168737G","G168741-","A168742-","A168743-","T168744-","A168748T","C168750G","G168755-","A168756-","T168757-","A168758-","G168759-","A168760-","G168761-","A168762-","A168763-","T168764-","C168765-","A168766-","T168767-","G168768-","C168769-","G168770-","T168771-","C168772-","A168773-","G168774-","A168775-","T168777G","C169569-","A169570-","T169571-","T169572-","T169573-","A169574-","A169575-","T169576-","A169577-","A169578-","G169579-","G169580-","A169581-","C169582-","A169583-","T169584-","T169585-","G169586-","G169587-","A169588-","T169589-","A169590-","T169591-","G169592-","T169593-","G169594-","G169595-","A169596-","A169597-","A169598-","A169599-","G169600-","T169601-","G169602-","A169603-","T169604-","G169605-","T169606-","A169607-","T169608-","G169609-","G169610-","A169611-","A169612-","G169613-","T169614-","T169615-","A169616-","G169617-","T169618-","A169619-","C169620-","A169621-","T169622-","T169623-","A169624-","T169625-","C169626-","A169627-","A169628-","C169629-","T169630-","T169631-","C169632-","T169633-","C169634-","C169635-","T169636-","T169637-","A169638-","T169639-","T169640-","G169641-","A169642-","T169643-","T169644-","G169645-","A169646-","A169647-","A169648-","A169649-","T169650-","G169651-","A169652-","A169653-","A169654-","A169655-","T169656-","A169657-","T169658-","A169659-","A169660-","A169661-","T169662-","A169663-","G169664-","T169665-","T169666-","T169667-","T169668-","T169669-","A169670-","T169671-","G169672-","T169673-","A169674-","T169675-","A169676-","G169677-","C169678-","G169679-","G169680-","T169681-","A169682-","T169683-","C169684-","T169685-","A169686-","C169687-","C169688-","C169689-","T169690-","A169691-","T169692-","A169693-","G169694-","T169695-","T169696-","T169697-","T169698-","A169699-","T169700-","T169701-","G169702-","C169703-","T169704-","T169705-","A169706-","C169707-","T169708-","A169709-","C169710-","T169711-","A169712-","A169713-","C169714-","A169715-","T169716-","G169717-","G169718-","A169719-","T169720-","T169721-","C169722-","A169723-","G169724-","A169725-","T169726-","A169727-","C169728-","A169729-","G169730-","A169731-","T169732-","A169733-","C169734-","A169735-","G169736-","A169737-","T169738-","A169739-","C169740-","A169741-","G169742-","A169743-","T169744-","A169745-","C169746-","A169747-","G169748-","A169749-","T169750-","A169751-","C169752-","A169753-","G169754-","A169755-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","T187263G","A187265-","G187266-","A187267-","A187268-","T187269-","C187270-","A187271-","T187272-","T187273-","T187274-","A187275-","T187276-","C187277-","A187278-","T187279-","A187280-","A187281-","C187282-","T187283-","A187284-","T187285-","G187286-","T187287-","T187288-","T187289-","A187290-","A187291-","T187292-","A187293-","A187294-","A187295-","T187296-","T187297-","C187298-","A187299-","T187300-","C187301-","A187302-","A187303-","C187304-","G187305-","A187306-","A187307-","T187308-","A187309-","T187310-","C187311-","G187312-","A187313-","T187314-","A187315-","A187316-","A187317-","G187318-","A187319-","C187320-","C187321-","T187322-","C187323-","T187324-","T187325-","G187326-","T187327-","A187328-","A187329-","T187330-","T187331-","C187332-","G187333-","A187334-","G187335-","T187336-","A187337-","T187338-","A187339-","G187340-","G187341-","A187342-","A187343-","G187344-","T187345-","A187346-","G187347-","T187348-","A187349-","T187350-","T187351-","A187352-","C187353-","C187354-","A187355-","T187356-","A187357-","T187358-","C187359-","A187360-","A187361-","C187362-","C187366T","A187372-","A187373-","C187374-","A187375-","A187376-","T187377-","T187378-","A187379-","C187380-","T187381-","C187382-","T187383-","A187384-","A187385-","A187386-","A187387-","C187388-","A187389-","T187390-","G187391-","A187392-","G187393-","G187394-","A187395-","T187396-","T187397-","G187398-","T187399-","A187400-","C187401-","T187402-","C187403-","C187404-","T187405-","G187406-","T187407-","C187408-","T187409-","T187410-","G187415-","G187416-","A187417-","G187418-","A187419-","T187420-","C187421-","A187422-","C187423-","T187424-","A187425-","T187426-","T187427-","T187428-","A187429-","G187430-","T187431-","C187432-","G187433-","T187434-","T187435-","G187436-","A187437-","T187438-","A187439-","A187440-","A187441-","C187442-","T187443-","A187444-","G187445-","T187446-","A187447-","A187448-","C187449-","C187450-","T187451-","C187452-","A187453-","G187454-","G187455-","T187456-","T187457-","T187458-","C187459-","T187460-","T187461-","T187462-","A187463-","C187464-","A187465-","A187466-","A187467-","C187468-","G187469-","A187470-","T187471-","A187472-","A187473-","A187474-","G187475-","T187476-","A187477-","C187478-","A187479-","A187480-","C187481-","A187482-","T187483-","C187484-","A187485-","A187486-","G187487-","A187488-","C187489-","C187490-","T187491-","C187492-","A187493-","C187494-","A187495-","A187496-","C187497-","A187498-","C187499-","A187500-","G187501-","T187502-","G187503-","C187504-","A187505-","A187506-","G187507-","A187508-","T187509-","T187510-","A187511-","A187512-","T187513-","C187514-","T187515-","A187516-","G187517-","A187518-","A187519-","A187520-","T187521-","C187522-","A187523-","A187524-","A187525-","T187526-","G187527-","T187528-","A187529-","A187530-","T187531-","T187532-","C187533-","T187534-","G187535-","G187536-","A187537-","G187538-","G187539-","C187545-","T187546-","A187547-","G187548-","A187549-","C187550-","A187551-","A187552-","C187553-","T187554-","A187555-","A187556-","C187557-","A187558-","C187559-","C187560-","C187561-","A187562-","C187563-","G187564-","G187565-","C187566-","G187567-","A187568-","A187569-","G187570-","T187571-","A187572-","T187573-","A187574-","C187575-","T187576-","T187577-","T187578-","A187579-","T187580-","G187581-","C187582-","C187583-","T187584-","C187585-","A187586-","T187587-","T187588-","C187589-","A187590-","G187591-","A187592-","A187593-","A187594-","C187595-","G187596-","G187597-","T187598-","A187599-","A187600-","C187601-","T187602-","G187603-","T187604-","A187605-","G187606-","T187607-","A187608-","G187609-","G187610-","A187611-","G187612-","A187613-","C187614-","T187615-","G187616-","T187617-","C187618-","T187619-","C187620-","T187621-","C187622-","T187623-","A187624-","A187625-","T187626-","C187627-","T187628-","C187629-","G187630-","A187631-","T187632-","G187633-","T187634-","A187635-","T187636-","A187637-","T187638-","A187639-","T187640-","A187641-","A187642-","T187643-","A187644-","T187645-","A187646-","T187647-","A187648-","C187649-","C187650-","A187651-","A187652-","T187653-","A187654-","C187655-","G187656-","G187657-","A187658-","C187659-","G187660-","C187661-","G187662-","A187663-","T187664-","A187665-","T187666-","A187667-","T187668-","T187669-","C187670-","C187671-","G187672-","A187673-","C187674-","A187675-","T187676-","G187677-","A187678-","A187679-","T187680-","G187681-","G187682-","C187683-","G187684-","T187685-","C187686-","G187687-","C187688-","T187689-","T187690-","A187691-","T187692-","C187693-","A187694-","T187695-","A187696-","T187697-","G187698-","T187699-","T187700-","A187701-","T187702-","A187703-","T187704-","C187705-","C187706-","T187707-","A187708-","A187709-","A187710-","T187711-","G187712-","T187713-","T187714-","G187715-","A187716-","T187717-","C187718-","A187719-","T187720-","A187721-","T187722-","T187723-","C187724-","C187725-","A187726-","C187727-","A187728-","A187729-","A187730-","T187731-","G187732-","A187733-","T187734-","T187735-","G187736-","T187737-","G187738-","A187739-","A187740-","C187741-","G187742-","A187743-","G187744-","A187745-","T187746-","T187747-","A187748-","A187749-","A187750-","T187751-","C187752-","A187753-","T187754-","C187755-","T187756-","A187757-","A187758-","C187759-","A187760-","A187761-","A187762-","T187763-","A187764-","A187765-","T187766-","T187767-","A187768-","G187769-","T187770-","T187771-","T187772-","T187773-","T187774-","T187775-","A187776-","T187777-","G187778-","A187779-","C187780-","A187781-","T187782-","T187783-","A187784-","A187785-","C187786-","A187787-","T187788-","A187789-","T187790-","A187791-","A187792-","T187793-","A187794-","A187795-","A187796-","T187797-","A187798-","A187799-","A187800-","T187801-","T187802-","A187803-","A187804-","T187805-","C187806-","A187807-","T187808-","T187809-","A187810-","T187811-","T187812-","G187813-","A187814-","C187815-","T187816-","T187817-","A187818-","A187819-","C187820-","G187821-","A187822-","T187823-","G187824-","A187825-","C187826-","G187827-","A187828-","A187829-","A187830-","G187831-","T187832-","T187833-","A187834-","T187835-","C187836-","A187837-","T187838-","T187839-","A187840-","T187841-","C187842-","T187843-","T187844-","A187845-","G187846-","G187847-","A187848-","T187849-","T187850-","C187851-","T187852-","T187853-","G187854-","A187855-","T187856-","T187857-","A187858-","T187859-","T187860-","A187861-","A187862-","T187863-","A187864-","C187865-","A187866-","A187867-","A187868-","T187869-","T187870-","C187871-","G187872-","T187873-","T187874-","T188117-","T188118-","A188119-","T188120-","C188121-","G188122-","T188123-","C188124-","T188125-","C188126-","C188127-","T188128-","T188129-","A188130-","A188131-","A188132-","G188133-","C188134-","T188135-","T188136-","C188137-","T188138-","G188139-","A188140-","T188141-","G188142-","G188143-","T188144-","A188145-","A188146-","C188147-","T188148-","G188149-","T188150-","G188151-","T188152-","T188153-","A188154-","C188155-","A188156-","T188157-","G188158-","T188159-","G188160-","C188161-","T188162-","C188163-","C188164-","T188165-","A188166-","A188167-","A188168-","A188169-","C188170-","A188171-","A188172-","A188173-","A188174-","T188175-","A188176-","T188177-","G188178-","G188179-","T188180-","C188181-","G188182-","T188183-","G188184-","T188185-","G188186-","T188187-","A188188-","C188189-","G188190-","G188191-","A188192-","A188193-","A188194-","G188195-","A188196-","A188197-","A188198-","G188199-","G188200-","A188201-","G188202-","A188203-","A188204-","A188205-","A188206-","T188207-","G188208-","A188209-","T188210-","A188211-","T188212-","G188213-","G188214-","A188215-","A188216-","T188217-","A188218-","C188219-","C188220-","A188221-","T188222-","T188223-","T188224-","G188225-","T188226-","A188227-","A188228-","G188229-","A188230-","A188231-","A188232-","T188233-","G188234-","T188235-","C188236-","G188237-","G188238-","A188239-","A188240-","G188241-","G188242-","G188243-","T188244-","A188245-","C188246-","T188247-","T188248-","A188249-","T188250-","T188251-","C188252-","A188253-","G188254-","A188255-","T188256-","A188257-","T188258-","T188259-","G188260-","T188261-","A188262-","T188263-","C188264-","T188265-","G188266-","A188267-","C188268-","T188269-","C188270-","T188271-","G188272-","A188273-","T188274-","C188275-","A188276-","A188277-","T188278-","G188279-","T188280-","A188281-","A188282-","A188283-","C188284-","C188285-","T188286-","A188287-","T188288-","G188289-","A188290-","C188291-","A188292-","A188293-","G188294-","A188295-","T188296-","A188297-","A188298-","G188299-","A188300-","C188301-","T188302-","T188303-","A188304-","C188305-","T188306-","C188307-","G188308-","C188309-","A188310-","T188311-","C188312-","T188313-","A188314-","C188315-","T188316-","G188317-","G188318-","A188319-","T188320-","A188321-","G188322-","A188323-","C188324-","A188325-","T188326-","A188327-","A188328-","A188329-","T188330-","A188331-","T188332-","C188333-","C188334-","T188335-","C188336-","C188337-","T188338-","C188339-","G188340-","T188341-","A188342-","A188343-","T188344-","A188345-","A188346-","T188347-","G188348-","A188349-","A188350-","A188351-","T188352-","A188353-","T188354-","A188355-","A188356-","T188357-","A188358-","T188359-","A188360-","C188361-","A188362-","C188363-","T188364-","A188365-","A188366-","T188367-","T188368-","A188369-","T188370-","T188371-","A188372-","A188373-","T188374-","A188375-","T188376-","C188377-","A188378-","A188379-","T188380-","C188381-","G188382-","A188383-","G188384-","T188385-","A188386-","T188387-","T188388-","A188389-","A188390-","C188391-","A188392-","T188393-","A188394-","T188395-","A188396-","A188397-","G188398-","T188399-","T188400-","A188401-","T188402-","T188403-","T188404-","T188405-","T188406-","A188407-","A188408-","A188409-","C188410-","C188411-","C188412-","C188413-","T188414-","T188415-","T188416-","T188417-","G188418-","G188419-","G188420-","T188421-","T188422-","C188423-","C188424-","G188425-","T188426-","C188427-","C188428-","T188429-","A188430-","A188431-","A188432-","C188433-","G188434-","G188435-","C188436-","G188437-","T188438-","T188439-","T188440-","C188441-","G188442-","G188443-","T188444-","C188445-","T188446-","G188447-","T188448-","G188449-","T188450-","C188451-","G188452-","C188453-","C188454-","A188455-","C188456-","C188457-","A188458-","T188459-","G188460-","G188461-","T188462-","C188463-","A188464-","C188465-","A188466-","C188467-","C188468-","G188469-","A188470-","G188471-","C188472-","C188473-","T188474-","C188475-","T188476-","G188477-","C188478-","G188479-","T188480-","G188481-","C188482-","T188483-","C188484-","C188485-","T188486-","C188487-","C188488-","A188489-","T188490-","C188491-","G188492-","A188493-","G188494-","G188495-","A188496-","C188497-","G188498-","A188499-","C188500-","T188501-","T188502-","C188503-","A188504-","A188505-","C188506-","T188507-","A188508-","T188509-","G188510-","A188511-","C188512-","A188513-","G188514-","C188515-","T188516-","C188517-","G188518-","G188519-","T188520-","G188521-","G188522-","C188523-","G188524-","T188525-","C188526-","T188527-","G188528-","C188529-","C188530-","A188531-","G188532-","C188533-","G188534-","T188535-","G188536-","T188537-","A188538-","C188539-","A188540-","T188541-","A188542-","C188543-","G188544-","A188545-","A188546-","T188547-","G188548-","G188549-","C188550-","A188551-","T188552-","T188553-","T188554-","C188555-","T188556-","A188557-","A188558-","G188559-","A188560-","A188561-","A188562-","A188563-","G188564-","T188565-","C188566-","T188567-","A188568-","C188569-","G188570-","G188571-","T188572-","A188573-","T188574-","C188575-","C188576-","T188577-","T188578-","T188579-","C188580-","T188581-","A188582-","C188583-","A188584-","A188585-","T188586-","T188587-","T188588-","C188589-","C188590-","T188591-","T188592-","T188593-","A188594-","A188595-","C188596-","A188597-","A188598-","C188599-","G188600-","G188601-","C188602-","A188603-","A188604-","C188605-","A188606-","G188607-","C188608-","T188609-","G188610-","C188611-","A188612-","G188613-","T188614-","A188615-","T188616-","T188617-","T188618-","T188619-","T188620-","A188621-","T188622-","A188623-","C188624-","T188625-","T188626-","T188627-","G188628-","A188629-","A188630-","T188631-","G188632-","C188633-","A188634-","T188635-","C188636-","G188637-","G188638-","A188639-","C188640-","A188641-","T188642-","T188643-","T188644-","A188645-","T188646-","A188647-","C188648-","A188649-","A188650-","G188651-","G188652-","G188653-","A188654-","G188655-","T188656-","C188657-","C188658-","T188659-","G188660-","T188661-","T188662-","C188663-","T188664-","A188665-","A188666-","T188667-","A188668-","T188669-","T188670-","G188671-","G188672-","C188673-","A188674-","T188675-","C188676-","A188677-","A188678-","T188679-","G188680-","T188681-","T188682-","C188683-","G188684-","G188685-","A188686-","T188687-","C188688-","T188689-","A188690-","T188691-","A188692-","G188693-","G188694-","C188695-","T188696-","T188697-","G188698-","A188699-","T188700-","T188701-","T188702-","T188703-","C188704-","G188705-","C188706-","A188707-","T188708-","T188709-","G188710-","A188711-","C188712-","T188713-","T188714-","T188715-","A188716-","C188717-","A188718-","C188719-","A188720-","G188721-","A188722-","C188723-","A188724-","T188725-","G188726-","A188727-","A188728-","C188729-","A188730-","T188731-","C188732-","C188733-","C188734-","C188735-","T188736-","G188737-","A188738-","A188739-","T188740-","C188741-","T188742-","G188743-","T188744-","A188745-","C188746-","A188747-","T188748-","A188749-","C188750-","T188751-","T188752-","T188753-","G188754-","T188755-","G188756-","G188757-","A188758-","T188759-","T188760-","T188761-","A188762-","C188763-","A188764-","C188765-","T188766-","G188767-","T188768-","T188769-","A188770-","G188771-","A188772-","A188773-","T188774-","C188775-","T188776-","C188777-","T188778-","A188779-","A188780-","C188781-","G188782-","C188783-","T188784-","G188785-","G188786-","C188787-","C188788-","T188789-","C188790-","T188791-","G188792-","T188793-","T188794-","G188795-","T188796-","T188797-","A188798-","C188799-","T188800-","T188801-","T188802-","C188803-","T188804-","A188805-","T188806-","G188807-","A188808-","T188809-","G188810-","C188811-","A188812-","C188813-","G188814-","T188815-","A188816-","T188817-","C188818-","G188819-","T188820-","T188821-","A188822-","T188823-","G188824-","C188825-","A188826-","A188827-","G188828-","C188829-","T188830-","T188831-","T188832-","C188833-","A188834-","T188835-","G188836-","T188837-","T188838-","G188839-","A188840-","C188841-","T188842-","A188843-","C188844-","T188845-","G188846-","C188847-","A188848-","G188849-","T188850-","G188851-","T188852-","T188853-","T188854-","C188855-","T188856-","T188857-","G188858-","C188859-","T188860-","C188861-","T188862-","G188863-","A188864-","C188865-","T188866-","A188867-","C188868-","A188869-","T188870-","A188871-","T188872-","A188873-","C188874-","T188875-","C188876-","T188877-","A188878-","C188879-","A188880-","A188881-","T188882-","C188883-","A188884-","A188885-","A188886-","G188887-","A188888-","A188890-","G188891-","A188892-","T188893-","T188894-","T188895-","C188896-","A188897-","G188898-","T188899-","A188900-","A188901-","A188902-","C188903-","T188904-","T188905-","G188906-","T188907-","A188908-","A188909-","C188910-","A188911-","G188912-","G188913-","A188914-","T188915-","T188916-","G188917-","T188918-","T188919-","T188920-","G188921-","C188922-","T188923-","G188924-","C188925-","T188926-","T188927-","T188928-","C188929-","T188930-","G188931-","G188932-","A188933-","T188934-","T188935-","T188936-","T188937-","A188938-","A188939-","T188940-","T188941-","T188942-","T188943-","G188944-","T188945-","C188946-","A188947-","G188948-","G188949-","A188950-","G188951-","T188952-","C188953-","T188954-","T188955-","G188956-","A188957-","G188958-","G188959-","A188960-","T188961-","A188962-","A188963-","A188964-","G188965-","T188966-","T188967-","T188968-","A188969-","A188970-","A188971-","A188972-","T188973-","A188974-","G188975-","A188976-","A188977-","T188978-","T188979-","A188980-","A188981-","T188982-","A188983-","A188984-","A188985-","G188986-","A188987-","A188988-","C188989-","A188990-","T188991-","A188992-","T188993-","A188994-","G188995-","G188996-","T188997-","C188998-","A188999-","T189000-","T189001-","T189002-","T189003-","T189004-","T189005-","A189006-","A189007-","A189008-","C189009-","A189010-","T189011-","G189012-","G189013-","A189014-","T189015-","A189016-","G189017-","A189018-","A189019-","A189020-","C189021-","C189022-","A189023-","A189024-","G189025-","T190132-","A190133-","T190134-","T190135-","A190136-","A190137-","T190138-","G190139-","G190140-","A190141-","T190142-","A190143-","T190144-","A190145-","T190146-","A190147-","G190148-","A190149-","T190150-","A190151-","A190152-","C190153-","G190154-","C190155-","A190156-","A190157-","T190158-","A190159-","G190160-","G190161-","G190162-","A190163-","C190164-","T190165-","A190166-","A190167-","T190168-","A190169-","G190170-","T190171-","A190172-","T190173-","T190174-","G190175-","T190176-","A190177-","A190178-","A190179-","A190180-","G190181-","A190182-","T190183-","A190184-","T190185-","G190345A"],"OPG071":["R246Q"],"OPG192":["T46-","D47-","D48-","N49-","N50-","E51-","L52-","V53-","L54-","N55-","F56-","K57-","E58-","Y59-","T60-","I61-","S62-","I63-","I64-","T65-","E66-","S67-","C68-","D69-","V70-","G71-","F72-","D73-","S74-","I75-","D76-","I77-","D78-","V79-","I80-","N81-","D82-","Y83-","K84-","I85-","I86-","D87-","M88-","Y89-","T90-"],"OPG195":["T118N","L119-","C120-","I121-","S122-","V123-","Y124-","C125-","D126-","Q127-","E128-","A129-","G130-","D131-","I172-","L210-","K211-","S212-","K213-","A214-","L215-","H216-"]},"labels":{"aa":"OPG071: R246Q; OPG192: T46-, D47-, D48-, N49-, N50-, E51-, L52-, V53-, L54-, N55-, F56-, K57-, E58-, Y59-, T60-, I61-, S62-, I63-, I64-, T65-, E66-, S67-, C68-, D69-, V70-, G71-, F72-, D73-, S74-, I75-, D76-, I77-, D78-, V79-, I80-, N81-, D82-, Y83-, K84-, I85-, I86-, D87-, M88-, Y89-, T90-; OPG195: T118N, L119-, C120-, I121-, S122-, V123-, Y124-, C125-, D126-, Q127-, E128-, A129-, G130-, D131-, I172-, L210-, K211-, S212-, K213-, A214-, L215-, H216-"}}},{"name":"NODE_0000006","node_attrs":{"div":19,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["C23353T","C51809T","G69678A","C125492T","C128174T","-188889A"],"OPG039":["D256N"],"OPG071":["R877Q"],"OPG146":["D50N"]},"labels":{"aa":"OPG039: D256N; OPG071: R877Q; OPG146: D50N"}},"children":[{"name":"NODE_0000007","node_attrs":{"div":20,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["T27971C","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","-173314A","-173315T","-173316A","-173317T"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}},"children":[{"name":"MK783033","node_attrs":{"div":30,"accession":"MK783033","author":{"author":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J.","value":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J."},"strain":{"value":"MK783033"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/MK783033/2017-10-09"},"country":{"value":"Nigeria"},"institution":{"value":"CDC, NCEZID/DHCPP/PRB"},"date":{"value":"2017-10-09"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["-608T","C25731T","C25768T","C26020T","A56968G","G102267T","C117099T","G129583A","C155707T","G161701A","T187428C"],"OPG042":["D360N"],"OPG074":["L53S"],"OPG121":["G160C"],"OPG136":["R830Q"],"OPG188":["V36I"]},"labels":{"aa":"OPG042: D360N; OPG074: L53S; OPG121: G160C; OPG136: R830Q; OPG188: V36I"}}},{"name":"OP535335","node_attrs":{"div":20,"accession":"OP535335","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"strain":{"value":"MPXV_Nigeria_2017_2947"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP535335/2017-10-XX"},"country":{"value":"Nigeria"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"date":{"value":"2017-10-XX"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000008","node_attrs":{"div":24,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["T607-","C92053T","C123000T","C146052T","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","C150831T","C151305T"],"OPG113":["S108L"],"OPG143":["E106K"]},"labels":{"aa":"OPG113: S108L; OPG143: E106K"}},"children":[{"name":"OP612677","node_attrs":{"div":27,"accession":"OP612677","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"strain":{"value":"MPXV/015/19"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP612677/2019-03-12"},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"date":{"value":"2019-03-12"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["C56351T","G74032A","T76087-","A89106-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","G190782A"],"OPG016":["E125K"],"OPG074":["E259K"],"OPG094":["A85T"]},"labels":{"aa":"OPG016: E125K; OPG074: E259K; OPG094: A85T"}}},{"name":"NODE_0000009","node_attrs":{"div":53,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["T606-","C2930T","C18493T","C18908T","G21898A","G23626A","C25254T","C29199T","G36901A","G44085A","G63034A","G75099A","G75144A","G76509A","C87659T","G115332A","C115572T","G122627A","C128771T","C140739T","A149394-","G151519T","G151875A","C160008T","C160312T","G165130A","G168862A","-173314A","-173315T","-173316A","-173317T","G174491A","G176289A","G176366A","C177703T","G194280A","A196614-","A196615-"],"OPG003":["E560K"],"OPG003_dup":["E560K"],"OPG037":["S179L"],"OPG039":["H165Y"],"OPG045":["E22K"],"OPG064":["S605L"],"OPG082":["S140L"],"OPG097":["H123Y"],"OPG109":["E597K"],"OPG133":["R42Q","S122F"],"OPG143":["T230M"],"OPG178":["G4V","D123N"],"OPG205":["A212T","M237I","S683L"]},"labels":{"aa":"OPG003: E560K; OPG003_dup: E560K; OPG037: S179L; OPG039: H165Y; OPG045: E22K; OPG064: S605L; OPG082: S140L; OPG097: H123Y; OPG109: E597K; OPG133: R42Q, S122F; OPG143: T230M; OPG178: G4V, D123N; OPG205: A212T, M237I, S683L"}},"children":[{"name":"OP413718","node_attrs":{"div":53,"accession":"OP413718","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"9000360"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP413718/2022-08-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["T133171-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"]}}},{"name":"OP536812","node_attrs":{"div":53,"accession":"OP536812","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"9000450"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP536812/2022-09-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000027","node_attrs":{"div":18,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["C23564T","C72362T","C83326T","G87230A","G87297A","G91728A","C119296T","C121320T","G125249A","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","G148412A","C164832T","C168120T"],"OPG092":["D196N"],"OPG105":["S734L"],"OPG109":["H740Y"],"OPG136":["D98N"],"OPG139":["A17T"],"OPG145":["E435K"],"OPG193":["L263F"]},"labels":{"aa":"OPG092: D196N; OPG105: S734L; OPG109: H740Y; OPG136: D98N; OPG139: A17T; OPG145: E435K; OPG193: L263F","clade":"A.1"}},"children":[{"name":"MT903343","node_attrs":{"div":21,"accession":"MT903343","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"strain":{"value":"MPXV-UK_P1"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/MT903343/2018-09-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2018-09-XX"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["-608T","G28838A","G92349A","-173314A","-173315T","-173316A","-173317T","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","G188494A","-196616A"],"OPG045":["A142V"],"OPG113":["E207K"]},"labels":{"aa":"OPG045: A142V; OPG113: E207K"}}},{"name":"MN648051","node_attrs":{"div":22,"accession":"MN648051","author":{"author":"Cohen Gihon,I.,Israeli,O.,Shifman,O.,Erez,N.,Melamed,S.,Paran,N.,Beth-Din,A.,Zvi,A.","value":"Cohen Gihon,I.,Israeli,O.,Shifman,O.,Erez,N.,Melamed,S.,Paran,N.,Beth-Din,A.,Zvi,A."},"strain":{"value":"MN648051"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Israel/MN648051/2018-10-04"},"country":{"value":"Israel"},"institution":{"value":"Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel"},"date":{"value":"2018-10-04"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["T607-","C8772T","C91363T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A147593T","G150568A","G177273A","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A196615-"],"OPG172":["E56V"],"OPG205":["D540N"]},"labels":{"aa":"OPG172: E56V; OPG205: D540N"}}},{"name":"MT903341","node_attrs":{"div":20,"accession":"MT903341","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"strain":{"value":"MPXV-M5320_M15_Bayelsa"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/MT903341/2018-08-14"},"country":{"value":"Nigeria"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2018-08-14"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["-608T","G3153-","A3154-","T3155-","T3156-","C3157-","G3158-","A3159-","A3160-","T3161-","C3162-","T3163-","C3164-","T3165-","T3166-","T3167-","G3168-","A3169-","G3170-","G3171-","A3172-","G3173-","A3174-","C3175-","T3176-","T3177-","A3178-","T3179-","G3180-","T3181-","C3182-","A3183-","C3184-","G3185-","A3186-","C3187-","T3188-","A3189-","C3190-","A3191-","T3192-","T3193-","T3194-","T3195-","T3196-","C3197-","G3198-","A3199-","T3200-","G3201-","A3202-","T3203-","G3204-","G3205-","A3206-","A3207-","T3208-","C3209-","T3210-","A3211-","T3212-","C3213-","T3214-","T3215-","A3216-","T3217-","C3218-","G3219-","A3220-","A3221-","T3222-","G3223-","A3224-","T3225-","A3226-","T3227-","A3228-","T3229-","T3230-","T3231-","T3232-","T3233-","C3234-","A3235-","T3236-","A3237-","A3238-","A3239-","T3240-","A3241-","C3242-","A3243-","C3244-","T3245-","T3246-","T3247-","T3248-","A3249-","T3250-","A3251-","G3252-","T3253-","C3254-","C3255-","T3256-","C3257-","G3258-","T3259-","T3260-","T3261-","A3262-","A3263-","A3264-","C3265-","A3266-","G3267-","A3268-","A3269-","T3270-","T3271-","T3272-","A3273-","G3274-","T3275-","A3276-","T3277-","G3278-","T3279-","A3280-","G3281-","T3282-","T3283-","C3284-","C3285-","G3286-","C3287-","A3288-","A3289-","A3290-","T3291-","G3292-","A3293-","C3294-","T3295-","C3296-","G3297-","T3298-","C3299-","C3300-","C3301-","T3302-","T3303-","A3304-","A3305-","T3306-","A3307-","G3308-","G3309-","C3310-","A3311-","G3312-","T3313-","A3314-","G3315-","G3316-","C3317-","T3318-","A3319-","T3320-","T3321-","A3322-","T3323-","C3324-","T3325-","T3326-","C3327-","T3328-","T3329-","T3330-","A3331-","C3332-","G3333-","T3334-","A3335-","G3336-","T3337-","G3338-","A3339-","T3340-","C3341-","G3342-","T3343-","C3344-","G3345-","T3346-","A3347-","G3348-","G3349-","G3350-","A3351-","G3352-","A3353-","G3354-","A3355-","A3356-","C3357-","T3358-","C3359-","C3360-","G3361-","A3362-","C3363-","A3364-","T3365-","C3366-","T3367-","T3368-","G3369-","T3370-","A3371-","G3372-","A3373-","A3374-","C3375-","A3376-","A3377-","C3378-","G3379-","A3380-","T3381-","T3382-","T3383-","A3384-","A3385-","T3386-","C3387-","A3388-","T3389-","A3390-","G3391-","G3392-","T3393-","A3394-","G3395-","A3396-","G3397-","A3398-","T3399-","A3400-","C3401-","T3402-","T3403-","T3404-","C3405-","A3406-","G3407-","T3408-","C3409-","T3410-","G3411-","T3412-","G3413-","G3414-","T3415-","G3416-","G3417-","A3418-","T3419-","A3420-","A3421-","T3422-","G3423-","T3424-","C3425-","A3426-","T3427-","T3428-","A3429-","A3430-","C3431-","G3432-","A3433-","C3434-","A3435-","T3436-","C3437-","C3438-","G3439-","C3440-","C3441-","T3442-","T3443-","G3444-","T3445-","A3446-","T3447-","A3448-","T3449-","A3450-","A3451-","T3452-","G3453-","T3454-","T3455-","T3456-","C3457-","T3458-","G3459-","T3460-","T3461-","T3462-","T3463-","C3464-","A3465-","A3466-","A3467-","C3468-","A3469-","C3470-","C3471-","A3472-","A3473-","G3474-","T3475-","C3476-","G3477-","A3478-","A3479-","T3480-","A3481-","C3482-","T3483-","G3484-","T3485-","C3486-","T3487-","T3488-","A3489-","T3490-","C3491-","G3492-","T3493-","C3494-","T3495-","T3496-","T3497-","A3498-","G3499-","T3500-","C3501-","G3502-","G3503-","A3504-","A3505-","G3506-","G3507-","T3508-","T3509-","G3510-","A3511-","T3512-","G3513-","T3514-","C3515-","G3516-","T3517-","A3518-","T3519-","C3520-","C3521-","G3522-","A3523-","T3524-","G3525-","T3526-","A3527-","T3528-","A3529-","C3530-","G3531-","A3532-","G3533-","G3534-","T3535-","A3536-","T3537-","G3538-","A3539-","G3540-","G3541-","C3542-","A3543-","A3544-","C3545-","A3546-","T3547-","T3548-","G3549-","T3550-","T3551-","A3552-","T3553-","T3554-","G3555-","C3556-","A3557-","A3558-","T3559-","T3560-","C3561-","T3562-","G3563-","G3564-","A3565-","A3566-","G3567-","G3568-","C3569-","G3570-","G3571-","T3572-","A3573-","T3574-","G3575-","A3576-","A3577-","G3578-","A3579-","G3580-","G3581-","A3582-","G3583-","T3584-","C3585-","A3586-","T3587-","T3588-","G3589-","T3590-","A3591-","T3592-","T3593-","A3594-","T3595-","A3596-","G3597-","T3598-","A3599-","T3600-","T3601-","C3602-","G3603-","T3604-","C3605-","T3606-","T3607-","T3608-","C3609-","T3610-","G3611-","A3612-","A3613-","T3614-","G3615-","T3616-","C3617-","G3618-","A3619-","A3620-","T3621-","C3622-","T3623-","A3624-","T3625-","C3626-","T3627-","A3628-","G3629-","T3630-","A3631-","G3632-","A3633-","T3634-","A3635-","C3636-","C3637-","G3638-","T3639-","A3640-","G3641-","T3642-","A3643-","T3644-","A3645-","T3646-","T3647-","G3648-","A3649-","G3650-","A3651-","G3652-","A3653-","G3654-","C3655-","G3656-","A3657-","C3658-","T3659-","T3660-","C3661-","C3662-","A3663-","T3664-","A3665-","T3666-","C3667-","C3668-","T3669-","T3670-","G3671-","A3672-","T3673-","T3674-","A3675-","T3676-","G3677-","T3678-","T3679-","T3680-","T3681-","A3682-","T3683-","G3684-","A3685-","A3686-","T3687-","A3688-","G3689-","A3690-","T3691-","A3692-","A3693-","A3694-","G3695-","T3696-","A3697-","G3698-","A3699-","T3700-","G3701-","T3702-","T3703-","G3704-","T3705-","C3706-","C3707-","T3708-","T3709-","C3710-","T3711-","T3712-","C3713-","C3714-","T3715-","T3716-","T3717-","T3718-","G3719-","T3720-","A3721-","A3722-","T3723-","T3724-","T3725-","C3726-","C3727-","C3728-","G3729-","T3730-","A3731-","T3732-","T3733-","T3734-","T3735-","T3736-","G3737-","T3738-","T3739-","C3740-","G3741-","T3742-","G3743-","C3744-","C3745-","A3746-","A3747-","T3748-","T3749-","G3750-","A3751-","G3752-","T3753-","A3754-","A3755-","C3756-","A3757-","T3758-","T3759-","A3760-","T3761-","G3762-","A3763-","G3764-","A3765-","A3766-","T3767-","A3768-","T3769-","G3770-","A3771-","C3772-","C3773-","T3774-","G3775-","T3776-","T3777-","G3778-","C3779-","A3780-","C3781-","A3782-","A3783-","T3784-","C3785-","G3786-","T3787-","T3788-","C3789-","T3790-","T3791-","T3792-","A3793-","T3794-","G3795-","T3796-","A3797-","T3798-","T3799-","C3800-","C3801-","A3802-","T3803-","G3804-","A3805-","T3806-","G3807-","G3808-","G3809-","T3810-","G3811-","T3812-","A3813-","C3814-","A3815-","A3816-","T3817-","C3818-","A3819-","A3820-","G3821-","A3822-","T3823-","T3824-","A3825-","T3826-","T3827-","A3828-","C3829-","G3830-","T3831-","A3832-","T3833-","C3834-","C3835-","T3836-","C3837-","G3838-","T3839-","A3840-","T3841-","C3842-","G3843-","G3844-","C3845-","T3846-","C3847-","C3848-","T3849-","C3850-","G3851-","A3852-","G3853-","A3854-","T3855-","A3856-","A3857-","A3858-","A3859-","G3860-","A3861-","G3862-","C3863-","A3864-","T3865-","A3866-","C3867-","A3868-","C3869-","C3870-","A3871-","C3872-","A3873-","C3874-","G3875-","A3876-","G3877-","G3878-","A3879-","C3880-","T3881-","A3882-","T3883-","G3884-","T3885-","T3886-","T3887-","G3888-","G3889-","T3890-","A3891-","T3892-","A3893-","C3894-","T3895-","G3896-","T3897-","T3898-","G3899-","A3900-","A3901-","G3902-","G3903-","T3904-","A3905-","A3906-","G3907-","T3908-","G3909-","T3910-","G3911-","T3912-","A3913-","A3914-","C3915-","G3916-","G3917-","C3918-","G3919-","T3920-","A3921-","T3922-","T3923-","T3924-","C3925-","C3926-","G3927-","A3928-","T3929-","T3930-","T3931-","T3932-","C3933-","G3934-","T3935-","A3936-","A3937-","C3938-","C3939-","G3940-","C3941-","G3942-","T3943-","T3944-","A3945-","A3946-","T3947-","G3948-","T3949-","T3950-","T3951-","G3952-","C3953-","T3954-","C3955-","C3956-","A3957-","T3958-","G3959-","A3960-","T3961-","C3962-","T3963-","A3964-","T3965-","T3966-","A3967-","T3968-","C3969-","G3970-","C3971-","G3972-","T3973-","A3974-","G3975-","A3976-","T3977-","G3978-","A3979-","A3980-","T3981-","C3982-","G3983-","C3984-","T3985-","T3986-","C3987-","T3988-","C3989-","A3990-","G3991-","C3992-","T3993-","C3994-","G3995-","C3996-","A3997-","T3998-","C3999-","T4000-","T4001-","A4002-","G4003-","T4004-","G4005-","T4006-","G4007-","A4008-","C4009-","T4010-","C4011-","T4012-","T4013-","T4014-","G4015-","A4016-","C4017-","T4018-","T4019-","G4020-","T4021-","A4022-","A4023-","T4024-","A4025-","A4026-","T4027-","T4028-","G4029-","C4030-","T4031-","T4032-","T4033-","C4034-","G4035-","T4036-","G4037-","G4038-","A4039-","A4040-","C4041-","G4042-","C4043-","G4044-","G4045-","A4046-","T4047-","A4048-","T4049-","G4050-","T4051-","G4052-","T4053-","T4054-","T4055-","A4056-","C4057-","A4058-","G4059-","T4060-","A4061-","G4062-","T4063-","A4064-","A4065-","T4066-","G4067-","A4068-","A4069-","G4070-","A4071-","G4072-","A4073-","A4074-","G4075-","T4076-","G4077-","A4078-","G4079-","T4080-","C4081-","C4082-","A4083-","T4084-","C4085-","C4086-","T4087-","C4088-","A4089-","T4090-","C4091-","G4092-","A4093-","C4094-","G4095-","C4096-","A4097-","A4098-","T4099-","T4100-","A4101-","G4102-","G4103-","G4104-","T4105-","C4106-","A4107-","G4108-","A4109-","T4110-","C4111-","C4112-","T4113-","T4114-","T4115-","A4116-","G4117-","T4118-","C4119-","A4120-","A4121-","T4122-","A4123-","A4124-","T4125-","T4126-","T4127-","G4128-","T4129-","A4130-","C4131-","A4132-","G4133-","A4134-","A4135-","C4136-","G4137-","T4138-","A4139-","A4140-","T4141-","A4142-","G4143-","T4144-","T4145-","T4146-","A4147-","A4148-","G4149-","C4150-","T4151-","C4152-","C4153-","C4154-","A4155-","T4156-","T4157-","G4158-","A4159-","A4160-","T4161-","T4162-","T4163-","A4164-","T4165-","A4166-","T4167-","C4168-","T4169-","A4170-","A4171-","G4172-","A4173-","T4174-","A4175-","A4176-","C4177-","A4178-","C4179-","A4180-","G4181-","C4182-","A4183-","A4184-","T4185-","A4186-","G4187-","A4188-","T4189-","C4190-","G4191-","G4192-","A4193-","T4194-","G4195-","A4196-","T4197-","T4198-","T4199-","A4200-","C4201-","T4202-","A4203-","A4204-","A4205-","G4206-","T4207-","C4208-","A4209-","T4210-","C4211-","A4212-","A4213-","T4214-","G4215-","G4216-","G4217-","G4218-","T4219-","C4220-","C4221-","G4222-","T4223-","T4224-","A4225-","G4226-","T4227-","A4228-","T4229-","A4230-","T4231-","C4232-","A4233-","A4234-","A4235-","G4236-","A4237-","T4238-","C4239-","T4240-","T4241-","G4242-","T4243-","T4244-","A4245-","T4246-","C4247-","G4248-","A4249-","T4250-","T4251-","G4252-","A4253-","T4254-","A4255-","G4256-","T4257-","G4258-","A4259-","A4260-","T4261-","G4262-","A4263-","A4264-","T4265-","C4266-","A4267-","G4268-","A4269-","T4270-","A4271-","G4272-","T4273-","G4274-","G4275-","T4276-","G4277-","T4278-","A4279-","G4280-","A4281-","G4282-","G4283-","A4284-","A4285-","T4286-","A4287-","T4288-","G4289-","T4290-","C4291-","C4292-","T4293-","T4294-","T4295-","T4296-","T4297-","T4298-","A4299-","T4300-","C4301-","C4302-","T4303-","T4304-","G4305-","C4306-","T4307-","A4308-","T4309-","C4310-","A4311-","A4312-","A4313-","G4314-","T4315-","T4316-","A4317-","C4318-","G4319-","C4320-","A4321-","T4322-","G4323-","C4324-","C4325-","G4326-","T4327-","G4328-","G4329-","C4330-","G4331-","T4332-","A4333-","A4334-","C4335-","A4336-","A4337-","T4338-","A4339-","T4340-","C4341-","T4342-","T4343-","T4344-","A4345-","A4346-","T4347-","A4348-","C4349-","A4350-","G4351-","A4352-","T4353-","G4354-","G4355-","A4356-","T4357-","T4358-","A4359-","A4360-","A4361-","T4362-","C4363-","G4364-","T4365-","G4366-","T4367-","A4368-","T4369-","T4370-","C4371-","A4372-","T4373-","C4374-","G4375-","T4376-","A4377-","T4378-","A4379-","G4380-","C4381-","A4382-","A4383-","T4384-","G4385-","T4386-","A4387-","A4388-","T4389-","G4390-","G4391-","A4392-","G4393-","A4394-","G4395-","T4396-","T4397-","A4398-","C4399-","C4400-","A4401-","C4402-","A4403-","T4404-","T4405-","T4406-","T4407-","A4408-","G4409-","T4410-","C4411-","G4412-","T4413-","T4414-","T4415-","A4416-","T4417-","T4418-","C4419-","A4420-","G4421-","A4422-","T4423-","C4424-","G4425-","C4426-","A4427-","G4428-","T4429-","G4430-","T4431-","T4432-","T4433-","A4434-","A4435-","T4436-","A4437-","A4438-","C4439-","T4440-","A4441-","A4442-","T4443-","T4444-","T4445-","A4446-","A4447-","A4448-","C4449-","A4450-","G4451-","A4452-","T4453-","G4454-","A4455-","G4456-","A4457-","T4458-","G4459-","A4460-","T4461-","A4462-","T4463-","A4464-","T4465-","C4466-","C4467-","A4468-","C4469-","A4470-","T4471-","C4472-","A4473-","A4474-","A4475-","G4476-","A4477-","A4478-","T4479-","G4480-","C4481-","G4482-","A4483-","G4484-","A4485-","T4486-","A4487-","C4488-","A4489-","T4490-","A4491-","T4492-","G4493-","A4494-","C4495-","A4496-","G4497-","A4498-","C4499-","A4500-","T4501-","T4502-","A4503-","T4504-","T4505-","G4506-","A4507-","C4508-","A4509-","G4510-","A4511-","A4512-","A4513-","T4514-","G4515-","T4516-","G4517-","A4518-","C4519-","C4520-","T4521-","T4522-","C4523-","A4524-","T4525-","T4526-","A4527-","T4528-","C4529-","A4530-","C4531-","C4532-","G4533-","T4534-","C4535-","G4536-","T4537-","C4538-","C4539-","A4540-","T4541-","A4542-","A4543-","A4544-","T4545-","G4546-","C4547-","G4548-","T4549-","T4550-","A4551-","G4552-","G4553-","T4554-","A4555-","C4556-","G4557-","T4558-","A4559-","C4560-","C4561-","A4562-","C4563-","A4564-","T4565-","A4566-","C4567-","T4568-","A4569-","T4570-","C4571-","G4572-","T4573-","T4574-","A4575-","A4576-","C4577-","G4578-","A4579-","T4580-","G4581-","C4582-","G4583-","C4584-","A4585-","C4586-","A4587-","A4588-","T4589-","C4590-","T4591-","C4592-","G4593-","T4594-","C4595-","C4596-","A4597-","T4598-","T4599-","T4600-","C4601-","A4602-","T4603-","C4604-","C4605-","A4606-","T4607-","C4608-","T4609-","T4610-","C4611-","A4612-","T4613-","A4614-","A4615-","T4616-","G4617-","A4618-","T4619-","T4620-","T4621-","A4622-","C4623-","T4624-","T4625-","T4626-","T4627-","T4628-","C4629-","A4630-","T4631-","A4632-","A4633-","T4634-","T4635-","A4636-","G4637-","A4638-","G4639-","A4640-","A4641-","A4642-","A4643-","A4644-","G4645-","A4646-","T4647-","C4648-","A4649-","A4650-","G4651-","G4652-","T4653-","A4654-","T4655-","A4656-","A4657-","A4658-","A4659-","A4660-","T4661-","T4662-","A4663-","G4664-","A4665-","A4666-","G4667-","T4668-","G4669-","T4670-","T4671-","A4672-","G4673-","A4674-","C4675-","T4676-","A4677-","T4678-","A4679-","A4680-","A4681-","C4682-","T4683-","A4684-","A4685-","C4686-","T4687-","T4688-","A4689-","T4690-","G4691-","A4692-","C4693-","T4694-","T4695-","A4696-","A4697-","C4698-","T4699-","A4700-","A4701-","C4702-","T4703-","T4704-","A4705-","T4706-","G4707-","A4708-","C4709-","T4710-","T4711-","A4712-","A4713-","C4714-","T4715-","A4716-","A4717-","C4718-","T4719-","T4720-","A4721-","T4722-","G4723-","A4724-","C4725-","T4726-","T4727-","A4728-","A4729-","C4730-","T4731-","A4732-","A4733-","C4734-","T4735-","T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","A4748-","A4749-","C4750-","T4751-","T4752-","A4753-","T4754-","G4755-","A4756-","C4757-","T4758-","T4759-","A4760-","A4761-","C4762-","T4763-","A4764-","A4765-","C4766-","T4767-","T4768-","A4769-","T4770-","G4771-","A4772-","C4773-","T4774-","T4775-","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","A4807-","T4808-","T4809-","A4810-","A4811-","C4812-","T4813-","C4814-","A4815-","T4816-","T4817-","T4818-","C4819-","A4820-","A4821-","G4822-","A4823-","A4824-","A4825-","G4826-","G4827-","T4828-","G4829-","G4830-","G4831-","T4832-","G4833-","G4834-","A4835-","T4836-","A4837-","G4838-","A4839-","A4840-","C4841-","T4842-","C4843-","T4844-","A4845-","T4846-","A4847-","T4848-","G4849-","A4850-","C4851-","A4852-","G4853-","C4854-","T4855-","T4856-","G4857-","T4858-","G4859-","A4860-","A4861-","A4862-","C4863-","A4864-","A4865-","T4866-","T4867-","A4868-","G4869-","A4870-","T4871-","C4872-","C4873-","C4874-","T4875-","A4876-","A4877-","T4878-","T4879-","T4880-","C4881-","T4882-","A4883-","A4884-","T4885-","G4886-","G4887-","A4888-","A4889-","G4890-","T4891-","T4892-","T4893-","T4894-","G4895-","A4896-","T4897-","A4898-","G4899-","G4900-","A4901-","G4902-","A4903-","T4904-","T4905-","G4906-","T4907-","C4908-","A4909-","T4910-","C4911-","A4912-","G4913-","T4914-","T4915-","G4916-","A4917-","T4918-","A4919-","C4920-","A4921-","T4922-","T4923-","G4924-","T4925-","T4926-","T4927-","A4928-","T4929-","T4930-","A4931-","T4932-","C4933-","T4934-","C4935-","A4936-","T4937-","C4938-","T4939-","A4940-","T4941-","T4942-","A4943-","G4944-","A4945-","G4946-","C4947-","A4948-","C4949-","G4950-","T4951-","C4952-","T4953-","G4954-","T4955-","T4956-","T4957-","A4958-","G4959-","A4960-","G4961-","C4962-","T4963-","T4964-","T4965-","A4966-","G4967-","T4968-","G4969-","A4970-","C4971-","C4972-","T4973-","G4974-","C4975-","T4976-","C4977-","G4978-","G4979-","T4980-","T4981-","A4982-","C4983-","T4984-","T4985-","C4986-","T4987-","G4988-","T4989-","G4990-","T4991-","A4992-","A4993-","A4994-","T4995-","C4996-","T4997-","T4998-","G4999-","A5000-","A5001-","T5002-","C5003-","C5004-","T5005-","T5006-","T5007-","A5008-","G5009-","T5010-","G5011-","A5012-","T5013-","A5014-","C5015-","A5016-","C5017-","T5018-","G5019-","T5020-","G5021-","T5022-","C5023-","A5024-","A5025-","A5026-","A5027-","C5028-","T5029-","G5030-","G5031-","A5032-","T5033-","G5034-","T5035-","T5036-","T5037-","A5038-","G5039-","A5040-","A5041-","T5042-","A5043-","C5044-","C5045-","T5046-","A5047-","T5048-","G5049-","T5050-","A5051-","G5052-","A5053-","A5054-","T5055-","A5056-","T5057-","G5058-","G5059-","G5060-","A5061-","A5062-","G5063-","C5064-","A5065-","T5066-","G5067-","C5068-","T5069-","T5070-","G5071-","T5072-","T5073-","T5074-","T5075-","T5076-","G5077-","T5078-","C5079-","T5080-","C5081-","T5082-","A5083-","T5084-","T5085-","A5086-","T5087-","A5088-","G5089-","A5090-","T5091-","T5092-","A5093-","A5094-","C5095-","T5096-","C5097-","A5098-","T5099-","A5100-","C5101-","A5102-","T5103-","G5104-","G5105-","T5106-","T5107-","G5108-","T5109-","A5110-","T5111-","T5112-","A5113-","T5114-","G5115-","A5116-","A5117-","T5118-","T5119-","T5120-","T5121-","C5122-","A5123-","T5124-","C5125-","T5126-","G5127-","C5128-","C5129-","T5130-","A5131-","A5132-","T5133-","G5134-","T5135-","A5136-","C5137-","T5138-","C5139-","C5140-","A5141-","A5142-","T5143-","T5144-","C5145-","T5146-","T5147-","G5148-","T5149-","T5150-","T5151-","A5152-","C5153-","A5154-","A5155-","T5156-","C5157-","A5158-","A5159-","T5160-","T5161-","A5162-","T5163-","A5164-","T5165-","A5166-","A5167-","T5168-","C5169-","A5170-","A5171-","A5172-","G5173-","A5174-","G5175-","T5176-","G5177-","A5178-","T5179-","G5180-","A5181-","T5182-","G5183-","C5184-","A5185-","T5186-","A5187-","C5188-","A5189-","C5190-","A5191-","T5192-","T5193-","A5194-","C5195-","A5196-","A5197-","A5198-","G5199-","T5200-","G5201-","A5202-","A5203-","T5204-","A5205-","A5206-","T5207-","C5208-","T5209-","A5210-","C5211-","C5212-","A5213-","T5214-","C5215-","A5216-","T5217-","A5218-","A5219-","A5220-","A5221-","T5222-","A5223-","C5224-","T5225-","T5226-","G5227-","A5228-","T5229-","A5230-","C5231-","A5232-","G5233-","A5234-","G5235-","C5236-","T5237-","T5238-","T5239-","A5240-","T5241-","C5242-","A5243-","C5244-","A5245-","T5246-","C5247-","A5248-","T5249-","G5250-","G5251-","T5252-","T5253-","T5254-","T5255-","C5256-","A5257-","A5258-","T5259-","T5260-","G5261-","T5262-","A5263-","T5264-","T5265-","A5266-","T5267-","T5268-","A5269-","A5270-","G5271-","T5272-","A5273-","T5274-","A5275-","G5276-","C5277-","T5278-","A5279-","A5280-","T5281-","T5282-","T5283-","T5284-","A5285-","T5286-","A5287-","C5288-","A5289-","G5290-","T5291-","C5292-","A5293-","A5294-","T5295-","A5296-","G5297-","A5298-","C5299-","A5300-","A5301-","T5302-","G5303-","G5304-","T5305-","T5306-","C5307-","T5308-","C5309-","T5310-","A5311-","A5312-","G5313-","C5314-","A5315-","A5316-","T5317-","A5318-","T5319-","T5320-","T5321-","C5322-","T5323-","A5324-","A5325-","T5326-","A5327-","T5328-","T5329-","T5330-","T5331-","A5332-","A5333-","G5334-","A5335-","T5336-","G5337-","T5338-","G5339-","C5340-","T5341-","T5342-","C5343-","C5344-","C5345-","T5346-","A5347-","C5348-","G5349-","G5350-","G5351-","C5352-","G5353-","A5354-","T5355-","G5356-","A5357-","C5358-","A5359-","G5360-","A5361-","T5362-","C5363-","C5364-","C5365-","C5366-","T5367-","A5368-","T5369-","C5370-","C5371-","A5372-","C5373-","G5374-","G5375-","C5376-","C5377-","A5378-","C5379-","G5380-","T5381-","C5382-","A5383-","A5384-","G5385-","A5386-","C5387-","A5388-","T5389-","G5390-","T5391-","A5392-","T5393-","A5394-","T5395-","C5396-","C5397-","A5398-","T5399-","T5400-","A5401-","C5402-","T5403-","C5404-","A5405-","T5406-","T5407-","A5408-","C5409-","T5410-","G5411-","C5412-","G5413-","T5414-","T5415-","G5416-","A5417-","C5418-","A5419-","T5420-","T5421-","T5422-","G5423-","C5424-","T5425-","C5426-","C5427-","A5428-","T5429-","T5430-","T5431-","T5432-","C5433-","T5434-","A5435-","A5436-","T5437-","A5438-","G5439-","C5440-","C5441-","A5442-","T5443-","G5444-","A5445-","T5446-","A5447-","C5448-","T5449-","A5450-","A5451-","A5452-","T5453-","C5454-","T5455-","A5456-","T5457-","A5458-","T5459-","A5460-","A5461-","C5462-","C5463-","T5464-","G5465-","C5466-","A5467-","T5468-","A5469-","G5470-","A5471-","T5472-","A5473-","G5474-","C5475-","G5476-","C5477-","G5478-","A5479-","T5480-","A5481-","A5482-","A5483-","G5484-","C5485-","A5486-","A5487-","G5488-","G5489-","T5490-","C5491-","C5492-","T5493-","T5494-","C5495-","C5496-","A5497-","C5498-","C5499-","A5500-","G5501-","C5502-","A5503-","T5504-","C5505-","T5506-","A5507-","G5508-","T5509-","T5510-","G5511-","A5512-","T5513-","T5514-","G5515-","A5516-","T5517-","A5518-","T5519-","C5520-","T5521-","T5522-","C5523-","A5524-","A5525-","T5526-","A5527-","T5528-","A5529-","T5530-","G5531-","G5532-","G5533-","A5534-","T5535-","A5536-","C5537-","A5538-","A5539-","A5540-","G5541-","C5542-","T5543-","T5544-","A5545-","T5546-","A5547-","A5548-","A5549-","T5550-","T5551-","T5552-","C5553-","T5554-","A5555-","A5556-","T5557-","A5558-","C5559-","T5560-","G5561-","T5562-","G5563-","G5564-","G5565-","T5566-","T5567-","C5568-","A5569-","T5570-","C5571-","T5572-","A5573-","C5574-","A5575-","A5576-","G5577-","G5578-","A5579-","A5580-","T5581-","C5582-","C5583-","C5584-","C5585-","T5586-","A5587-","G5588-","T5589-","A5590-","T5591-","A5592-","C5593-","T5594-","G5595-","A5596-","A5597-","T5598-","T5599-","A5600-","T5601-","T5602-","T5603-","T5604-","A5605-","T5606-","A5607-","T5608-","A5609-","G5610-","A5611-","T5612-","C5613-","T5614-","A5615-","A5616-","T5617-","T5618-","T5619-","A5620-","A5621-","C5622-","A5623-","T5624-","C5625-","A5626-","T5627-","T5628-","T5629-","T5630-","C5631-","A5632-","T5633-","C5634-","T5635-","G5636-","G5637-","G5638-","A5639-","T5640-","A5641-","C5642-","C5643-","A5644-","C5645-","A5646-","A5647-","T5648-","T5649-","C5650-","A5651-","A5652-","A5653-","A5654-","T5655-","A5656-","A5657-","A5658-","C5659-","T5660-","C5661-","A5662-","A5663-","C5664-","A5665-","A5666-","C5667-","A5668-","C5669-","T5670-","A5671-","C5672-","T5673-","T5674-","T5675-","C5676-","C5677-","T5678-","T5679-","T5680-","T5681-","T5682-","A5683-","C5684-","A5685-","T5686-","A5687-","T5688-","T5689-","C5690-","C5691-","C5692-","C5693-","T5694-","A5695-","A5696-","A5697-","A5698-","T5699-","A5700-","G5701-","G5702-","C5703-","A5704-","T5705-","T5706-","C5707-","A5708-","A5709-","G5710-","C5711-","A5712-","T5713-","T5714-","C5715-","T5716-","A5717-","T5718-","T5719-","T5720-","T5721-","A5722-","T5723-","A5724-","T5725-","A5726-","T5727-","T5728-","A5729-","C5730-","A5731-","G5732-","C5733-","C5734-","C5735-","C5736-","A5737-","T5738-","G5739-","A5740-","T5741-","C5742-","T5743-","A5744-","C5745-","C5746-","A5747-","T5748-","A5749-","A5750-","G5751-","A5752-","T5753-","C5754-","A5755-","A5756-","C5757-","A5758-","A5759-","T5760-","G5761-","T5762-","C5763-","T5764-","A5765-","T5766-","T5767-","T5768-","C5769-","T5770-","A5771-","C5772-","A5773-","T5774-","A5775-","T5776-","G5777-","C5778-","A5779-","T5780-","T5781-","A5782-","G5783-","A5784-","T5785-","A5786-","G5787-","A5788-","T5789-","A5790-","G5791-","T5792-","A5793-","A5794-","A5795-","G5796-","T5797-","A5798-","A5799-","G5800-","A5801-","G5802-","A5803-","T5804-","C5805-","T5806-","T5807-","G5808-","C5809-","A5810-","C5811-","A5812-","G5813-","A5814-","A5815-","T5816-","T5817-","A5818-","C5819-","A5820-","A5821-","T5822-","T5823-","C5824-","T5825-","T5826-","A5827-","A5828-","T5829-","A5830-","A5831-","T5832-","T5833-","A5834-","T5835-","A5836-","G5837-","A5838-","G5839-","A5840-","A5841-","A5842-","A5843-","T5844-","A5845-","T5846-","C5847-","T5848-","T5849-","C5850-","C5851-","A5852-","T5853-","A5854-","T5855-","A5856-","A5857-","T5858-","T5859-","C5860-","T5861-","T5862-","T5863-","G5864-","A5865-","C5866-","A5867-","C5868-","T5869-","A5870-","A5871-","T5872-","G5873-","C5874-","A5875-","G5876-","A5877-","T5878-","A5879-","T5880-","A5881-","A5882-","T5883-","A5884-","T5885-","C5886-","T5887-","T5888-","T5889-","A5890-","T5891-","A5892-","T5893-","G5894-","T5895-","A5896-","A5897-","T5898-","A5899-","T5900-","A5901-","T5902-","G5903-","C5904-","A5905-","A5906-","A5907-","C5908-","A5909-","G5910-","T5911-","C5912-","T5913-","A5914-","T5915-","C5916-","T5917-","A5918-","C5919-","T5920-","A5921-","T5922-","A5923-","T5924-","A5925-","C5926-","T5927-","G5928-","A5929-","T5930-","C5931-","A5932-","A5933-","T5934-","A5935-","T5936-","T5937-","A5938-","T5939-","C5940-","T5941-","C5942-","T5943-","A5944-","T5945-","G5946-","A5947-","A5948-","T5949-","C5950-","C5951-","T5952-","A5953-","A5954-","A5955-","A5956-","T5957-","A5958-","A5959-","T5960-","C5961-","A5962-","T5963-","A5964-","C5965-","A5966-","G5967-","A5968-","A5969-","C5970-","A5971-","T5972-","C5973-","T5974-","A5975-","C5976-","A5977-","G5978-","G5979-","A5980-","T5981-","C5982-","A5983-","C5984-","A5985-","A5986-","A5987-","T5988-","T5989-","G5990-","G5991-","T5992-","T5993-","C5994-","A5995-","A5996-","G5997-","G5998-","A5999-","G6000-","A6001-","A6002-","A6003-","T6004-","C6005-","T6006-","A6007-","T6008-","C6009-","A6010-","A6011-","A6012-","T6013-","A6014-","T6015-","T6016-","T6017-","T6018-","C6019-","C6020-","T6021-","G6022-","T6023-","C6024-","A6025-","A6026-","C6027-","A6028-","A6029-","C6030-","T6031-","G6032-","G6033-","T6034-","T6035-","C6036-","T6037-","A6038-","G6039-","A6040-","A6041-","C6042-","A6043-","T6044-","A6045-","A6046-","C6047-","A6048-","G6049-","T6050-","C6051-","A6052-","A6053-","C6054-","A6055-","C6056-","C6057-","T6058-","A6059-","A6060-","T6061-","C6062-","C6063-","A6064-","T6065-","G6066-","T6067-","T6068-","T6069-","T6070-","T6071-","T6072-","A6073-","T6074-","A6075-","A6076-","T6077-","C6078-","A6079-","T6080-","C6081-","T6082-","A6083-","C6084-","C6085-","A6086-","A6087-","A6088-","G6089-","A6090-","T6091-","A6092-","A6093-","T6094-","G6095-","A6096-","C6097-","C6098-","A6099-","A6100-","A6101-","G6102-","A6103-","T6104-","C6105-","G6106-","A6107-","G6108-","G6109-","T6110-","C6111-","G6112-","T6113-","C6114-","G6115-","T6116-","G6117-","A6118-","A6119-","A6120-","C6121-","T6122-","G6123-","C6124-","T6125-","C6126-","A6127-","T6128-","C6129-","G6130-","A6131-","C6132-","A6133-","G6134-","C6135-","C6136-","A6137-","T6138-","G6139-","A6140-","A6141-","A6142-","T6143-","C6144-","T6145-","A6146-","C6147-","C6148-","G6149-","A6150-","C6151-","T6152-","C6153-","C6154-","A6155-","T6156-","G6157-","G6158-","T6159-","G6160-","C6161-","G6162-","A6163-","A6164-","T6165-","C6166-","G6167-","C6168-","A6169-","C6170-","T6171-","G6172-","T6173-","C6174-","T6175-","T6176-","A6177-","T6178-","T6179-","C6180-","G6181-","C6182-","C6183-","A6184-","T6185-","T6186-","G6187-","A6188-","T6189-","T6190-","T6191-","T6192-","C6193-","A6194-","T6195-","T6196-","T6197-","T6198-","T6199-","T6200-","A6201-","T6202-","A6203-","A6204-","T6205-","T6206-","A6207-","T6208-","G6209-","T6210-","A6211-","C6212-","A6213-","T6214-","G6215-","T6216-","T6217-","T6218-","T6219-","C6220-","C6221-","T6222-","T6223-","C6224-","T6225-","A6226-","T6227-","T6228-","C6229-","T6230-","C6231-","A6232-","A6233-","G6234-","A6235-","G6236-","T6237-","C6238-","T6239-","A6240-","C6241-","A6242-","A6243-","A6244-","A6245-","A6246-","T6247-","A6248-","T6249-","A6250-","T6251-","T6252-","T6253-","T6254-","T6255-","T6256-","C6257-","G6258-","A6259-","T6260-","A6261-","T6262-","C6263-","T6264-","A6265-","A6266-","G6267-","T6268-","A6269-","C6270-","T6271-","A6272-","A6273-","G6274-","T6275-","T6276-","T6277-","T6278-","T6279-","T6280-","T6281-","A6282-","C6283-","T6284-","G6285-","T6286-","T6287-","T6288-","T6289-","T6290-","G6291-","T6292-","T6293-","A6294-","C6295-","T6296-","G6297-","T6298-","C6299-","T6300-","T6301-","C6302-","C6303-","A6304-","T6305-","T6306-","C6307-","T6308-","T6309-","C6310-","T6311-","A6312-","A6313-","C6314-","T6315-","A6316-","A6317-","A6318-","G6319-","A6320-","T6321-","C6322-","T6323-","G6324-","A6325-","G6326-","A6327-","T6328-","A6329-","A6330-","A6331-","T6332-","T6333-","A6334-","T6335-","A6336-","C6337-","A6338-","A6339-","T6340-","C6341-","T6342-","T6343-","C6344-","G6345-","C6346-","T6347-","A6348-","T6349-","C6350-","G6351-","A6352-","A6353-","C6354-","C6355-","A6356-","T6357-","T6358-","T6359-","T6360-","T6361-","G6362-","T6363-","A6364-","G6365-","T6366-","C6367-","T6368-","A6369-","A6370-","A6371-","G6372-","C6373-","C6374-","T6375-","G6376-","A6377-","A6378-","G6379-","T6380-","A6381-","A6382-","T6383-","T6384-","A6385-","A6386-","C6387-","C6388-","A6389-","A6390-","C6391-","T6392-","G6393-","T6394-","T6395-","T6396-","T6397-","T6398-","A6399-","T6400-","T6401-","A6402-","G6403-","T6404-","G6405-","G6406-","C6407-","T6408-","T6409-","T6410-","T6411-","T6412-","T6413-","C6414-","G6415-","A6416-","T6417-","C6418-","T6419-","A6420-","T6421-","C6422-","C6423-","T6424-","C6425-","G6426-","T6427-","C6428-","C6429-","T6430-","C6431-","T6432-","C6433-","A6434-","T6435-","C6436-","A6437-","T6438-","C6439-","C6440-","T6441-","T6442-","A6443-","T6444-","A6445-","T6446-","T6447-","A6448-","T6449-","T6450-","A6451-","T6452-","C6453-","A6454-","T6455-","T6456-","A6457-","T6458-","T6459-","A6460-","T6461-","C6462-","A6463-","T6464-","A6465-","G6466-","T6467-","C6468-","T6469-","A6470-","T6471-","T6472-","A6473-","A6474-","A6475-","C6476-","A6477-","C6478-","A6479-","A6480-","A6481-","T6482-","C6483-","A6484-","T6485-","C6486-","T6487-","A6488-","C6489-","G6490-","T6491-","T6492-","T6493-","A6494-","T6495-","A6496-","A6497-","C6498-","A6499-","A6500-","C6501-","A6502-","T6503-","T6504-","C6505-","T6506-","C6507-","A6508-","T6509-","T6510-","A6511-","T6512-","T6513-","A6514-","A6515-","T6516-","T6517-","A6518-","G6519-","T6520-","T6521-","C6522-","T6523-","G6524-","T6525-","A6526-","G6527-","A6528-","A6529-","T6530-","A6531-","T6532-","C6533-","T6534-","T6535-","T6536-","A6537-","A6538-","T6539-","A6540-","A6541-","T6542-","T6543-","T6544-","G6545-","G6546-","C6547-","T6548-","A6549-","T6550-","A6551-","C6552-","A6553-","T6554-","C6555-","T6556-","G6557-","T6558-","T6559-","C6560-","A6561-","A6562-","T6563-","A6564-","C6565-","T6566-","A6567-","T6568-","C6569-","T6570-","A6571-","T6572-","T6573-","G6574-","A6575-","T6576-","G6577-","A6578-","T6579-","T6580-","T6581-","C6582-","T6583-","T6584-","T6585-","T6586-","T6587-","T6588-","A6589-","A6590-","G6591-","A6592-","C6593-","T6594-","T6595-","A6596-","A6597-","A6598-","C6599-","T6600-","A6601-","G6602-","T6603-","T6604-","A6605-","T6606-","G6607-","G6608-","T6609-","A6610-","A6611-","T6612-","G6613-","A6614-","C6615-","G6616-","A6617-","T6618-","G6619-","A6620-","A6621-","A6622-","T6623-","C6624-","G6625-","A6626-","G6627-","T6628-","A6629-","G6630-","T6631-","A6632-","A6633-","C6634-","T6635-","T6636-","C6637-","T6638-","A6639-","A6640-","T6641-","A6642-","A6643-","A6644-","G6645-","A6646-","C6647-","T6648-","T6649-","G6650-","A6651-","T6652-","A6653-","T6654-","C6655-","A6656-","T6657-","T6658-","A6659-","T6660-","C6661-","A6662-","T6663-","A6664-","T6665-","G6666-","T6667-","T6668-","T6669-","G6670-","A6671-","T6672-","C6673-","G6674-","T6675-","C6676-","A6677-","T6678-","A6679-","G6680-","T6681-","T6682-","A6683-","A6684-","T6685-","A6686-","G6687-","T6688-","G6689-","T6690-","G6691-","G6692-","C6693-","T6694-","A6695-","A6696-","A6697-","T6698-","G6699-","G6700-","T6701-","A6702-","C6703-","T6704-","G6705-","T6706-","T6707-","A6708-","A6709-","T6710-","A6711-","A6712-","G6713-","T6714-","T6715-","T6716-","A6717-","T6718-","A6719-","G6720-","A6721-","C6722-","A6723-","A6724-","T6725-","A6726-","T6727-","C6728-","A6729-","T6730-","A6731-","G6732-","T6733-","A6734-","T6735-","T6736-","T6737-","T6738-","C6739-","T6740-","T6741-","T6742-","C6743-","C6744-","A6745-","G6746-","A6747-","A6748-","T6749-","T6750-","A6751-","G6752-","A6753-","T6754-","T6755-","A6756-","T6757-","T6758-","T6759-","T6760-","T6761-","T6762-","T6763-","A6764-","A6765-","A6766-","T6767-","A6768-","C6769-","T6770-","G6771-","A6772-","T6773-","C6774-","C6775-","T6776-","C6777-","A6778-","C6779-","A6780-","A6781-","T6782-","T6783-","C6784-","C6785-","G6786-","T6787-","G6788-","A6789-","T6790-","G6791-","T6792-","A6793-","G6794-","C6795-","A6796-","G6797-","T6798-","A6799-","G6800-","T6801-","T6802-","G6803-","G6804-","T6805-","G6806-","C6807-","A6808-","T6809-","G6810-","G6811-","T6812-","C6813-","T6814-","A6815-","T6816-","A6817-","T6818-","C6819-","G6820-","T6821-","T6822-","A6823-","A6824-","A6825-","A6826-","T6827-","G6828-","T6829-","A6830-","T6831-","C6832-","A6833-","T6834-","A6835-","T6836-","A6837-","T6838-","A6839-","A6840-","T6841-","A6842-","G6843-","T6844-","T6845-","T6846-","T6847-","C6848-","T6849-","G6850-","A6851-","C6852-","G6853-","T6854-","G6855-","G6856-","A6857-","G6858-","T6859-","A6860-","C6861-","A6862-","G6863-","A6864-","A6865-","T6866-","T6867-","T6868-","T6869-","C6870-","G6871-","A6872-","T6873-","T6874-","A6875-","A6876-","T6877-","G6878-","A6879-","G6880-","T6881-","T6882-","C6883-","A6884-","T6885-","G6886-","G6887-","T6888-","A6889-","A6890-","G6891-","G6892-","A6893-","A6894-","G6895-","G6896-","G6897-","C6898-","A6899-","A6900-","A6901-","T6902-","G6903-","C6904-","C6905-","T6906-","G6907-","T6908-","A6909-","T6910-","A6911-","T6912-","A6913-","A6914-","T6915-","A6916-","T6917-","A6918-","C6919-","A6920-","T6921-","A6922-","A6923-","G6924-","T6925-","T6926-","A6927-","A6928-","T6929-","A6930-","G6931-","T6932-","T6933-","T6934-","T6935-","T6936-","T6937-","A6938-","T6939-","C6940-","A6941-","T6942-","A6943-","T6944-","T6945-","T6946-","T6947-","C6948-","T6949-","A6950-","A6951-","T6952-","A6953-","C6954-","C6955-","A6956-","T6957-","A6958-","A6959-","T6960-","A6961-","A6962-","A6963-","A6964-","A6965-","T6966-","T6967-","A6968-","T6969-","C6970-","A6971-","T6972-","T6973-","A6974-","T6975-","T6976-","G6977-","C6978-","G6979-","T6980-","T6981-","T6982-","G6983-","G6984-","T6985-","A6986-","G6987-","T6988-","T6989-","C6990-","T6991-","G6992-","C6993-","C6994-","C6995-","T6996-","A6997-","T6998-","C6999-","A7000-","T7001-","C7002-","T7003-","A7004-","T7005-","A7006-","T7007-","C7008-","A7009-","C7010-","T7011-","G7012-","T7013-","C7014-","A7015-","C7016-","T7017-","C7018-","T7019-","C7020-","G7021-","C7022-","T7023-","C7024-","T7025-","C7026-","A7027-","C7028-","T7029-","A7030-","T7031-","A7032-","T7033-","C7034-","T7035-","T7036-","C7037-","T7038-","A7039-","A7040-","A7041-","A7042-","T7043-","T7044-","A7045-","C7046-","A7047-","A7048-","A7049-","C7050-","A7051-","A7052-","C7053-","T7054-","G7055-","G7056-","A7057-","T7058-","A7059-","T7060-","T7061-","C7062-","G7063-","A7064-","T7065-","A7066-","A7067-","C7068-","A7069-","G7070-","C7071-","A7072-","T7073-","T7074-","T7075-","G7076-","T7077-","G7078-","T7079-","A7080-","G7081-","T7082-","T7083-","T7084-","T7085-","T7086-","G7087-","T7088-","C7089-","T7090-","T7091-","T7092-","T7093-","A7094-","C7095-","A7096-","G7097-","T7098-","A7099-","T7100-","A7101-","T7102-","A7103-","C7104-","G7105-","T7106-","T7107-","A7108-","T7109-","T7110-","G7111-","T7112-","C7113-","A7114-","A7115-","A7116-","A7117-","T7118-","C7119-","T7120-","A7121-","A7122-","A7123-","C7124-","A7125-","A7126-","A7127-","T7128-","A7129-","T7130-","T7131-","A7132-","G7133-","C7134-","A7135-","T7136-","A7137-","A7138-","T7139-","A7140-","C7141-","A7142-","T7143-","C7144-","T7145-","A7146-","T7147-","C7148-","T7149-","A7150-","T7151-","A7152-","A7153-","G7154-","A7155-","T7156-","C7157-","A7158-","G7159-","G7160-","A7161-","T7162-","C7163-","C7164-","A7165-","T7166-","G7167-","T7168-","T7169-","C7170-","G7171-","A7172-","G7173-","C7174-","A7175-","T7176-","A7177-","C7178-","T7179-","A7180-","G7181-","C7182-","C7183-","A7184-","T7185-","G7186-","T7187-","A7188-","T7189-","A7190-","T7191-","T7192-","T7193-","G7194-","T7195-","A7196-","A7197-","C7198-","T7199-","T7200-","C7201-","G7202-","T7203-","C7204-","G7205-","T7206-","A7207-","C7208-","A7209-","G7210-","C7211-","G7212-","T7213-","T7214-","A7215-","G7216-","A7217-","T7218-","C7219-","A7220-","A7221-","T7222-","A7223-","G7224-","A7225-","A7226-","T7227-","A7228-","A7229-","A7230-","C7231-","A7232-","A7233-","T7234-","C7235-","G7236-","T7237-","G7238-","T7239-","G7240-","A7241-","C7242-","G7243-","C7244-","A7245-","A7246-","C7247-","T7248-","T7249-","T7250-","T7251-","T7252-","T7253-","A7254-","C7255-","G7256-","A7257-","T7258-","C7259-","T7260-","A7261-","G7262-","T7263-","T7264-","G7265-","T7266-","A7267-","T7268-","G7269-","A7270-","G7271-","T7272-","T7273-","T7274-","A7275-","T7276-","C7277-","G7278-","T7279-","T7280-","T7281-","A7282-","C7283-","A7284-","T7285-","A7286-","A7287-","G7288-","C7289-","A7290-","A7291-","T7292-","T7293-","A7294-","A7295-","C7296-","G7297-","G7298-","C7299-","T7300-","T7301-","T7302-","A7303-","A7304-","C7305-","A7306-","G7307-","A7308-","T7309-","G7310-","A7311-","T7312-","C7313-","T7314-","G7315-","A7316-","G7317-","T7318-","A7319-","A7320-","T7321-","A7322-","A7323-","T7324-","A7325-","T7326-","A7327-","C7328-","C7329-","T7330-","C7331-","T7332-","G7333-","T7334-","T7335-","A7336-","T7337-","A7338-","C7339-","G7340-","T7341-","T7342-","T7343-","A7344-","A7345-","T7346-","G7347-","T7348-","T7349-","C7350-","A7351-","C7352-","G7353-","G7354-","T7355-","C7356-","T7357-","T7358-","A7359-","G7360-","T7361-","A7362-","T7363-","T7364-","T7365-","T7366-","T7367-","A7368-","G7369-","A7370-","T7371-","A7372-","T7373-","C7374-","A7375-","A7376-","T7377-","T7378-","G7379-","T7380-","G7381-","A7382-","T7383-","T7384-","T7385-","A7386-","C7387-","A7388-","C7389-","C7390-","A7391-","T7392-","A7393-","T7394-","T7395-","C7396-","G7397-","A7398-","C7399-","T7400-","C7401-","C7402-","C7403-","T7404-","T7405-","G7406-","T7407-","G7408-","T7409-","G7410-","T7411-","A7412-","A7413-","C7414-","G7415-","T7416-","T7417-","A7418-","G7419-","A7420-","A7421-","A7422-","T7423-","T7424-","C7425-","T7426-","A7427-","A7428-","A7429-","T7430-","C7431-","T7432-","A7433-","T7434-","A7435-","T7436-","T7437-","A7438-","T7439-","C7440-","T7441-","A7442-","T7443-","T7444-","A7445-","C7446-","A7447-","G7448-","C7449-","G7450-","T7451-","A7452-","A7453-","A7454-","A7455-","C7456-","A7457-","C7458-","A7459-","T7460-","T7461-","C7462-","A7463-","A7464-","T7465-","A7466-","T7467-","T7468-","G7469-","T7470-","A7471-","T7472-","T7473-","G7474-","T7475-","T7476-","A7477-","T7478-","T7479-","T7480-","T7481-","T7482-","A7483-","T7484-","A7485-","T7486-","T7487-","A7488-","T7489-","T7490-","T7491-","A7492-","C7493-","A7494-","C7495-","A7496-","A7497-","T7498-","T7499-","A7500-","A7501-","C7502-","A7503-","A7504-","T7505-","G7506-","T7507-","A7508-","T7509-","T7510-","A7511-","T7512-","T7513-","A7514-","G7515-","T7516-","T7517-","T7518-","A7519-","T7520-","A7521-","T7522-","T7523-","A7524-","C7525-","T7526-","G7527-","A7528-","A7529-","T7530-","T7531-","A7532-","A7533-","T7534-","A7535-","A7536-","T7537-","A7538-","T7539-","A7540-","A7541-","A7542-","A7543-","T7544-","T7545-","C7546-","C7547-","C7548-","A7549-","A7550-","T7551-","C7552-","T7553-","T7554-","G7555-","T7556-","C7557-","A7558-","T7559-","A7560-","A7561-","A7562-","C7563-","A7564-","C7565-","A7566-","A7567-","A7568-","A7569-","T7570-","C7571-","C7572-","A7573-","T7574-","T7575-","A7576-","A7577-","A7578-","A7579-","A7580-","T7581-","G7582-","T7583-","C7584-","G7585-","A7586-","T7587-","A7588-","A7589-","A7590-","A7591-","T7592-","A7593-","T7594-","C7595-","T7596-","G7597-","A7598-","T7599-","G7600-","T7601-","T7602-","G7603-","T7604-","T7605-","G7606-","T7607-","T7608-","C7609-","G7610-","C7611-","T7612-","G7613-","C7614-","T7615-","A7616-","T7617-","G7618-","A7619-","T7620-","A7621-","A7622-","T7623-","C7624-","A7625-","G7626-","A7627-","T7628-","C7629-","A7630-","T7631-","T7632-","A7633-","G7634-","C7635-","C7636-","G7637-","A7638-","T7639-","A7640-","G7641-","T7642-","G7643-","G7644-","T7645-","A7646-","A7647-","T7648-","G7649-","C7650-","T7651-","A7652-","T7653-","C7654-","G7655-","A7656-","A7657-","A7658-","C7659-","A7660-","A7661-","C7662-","A7663-","T7664-","C7665-","G7666-","C7667-","C7668-","A7669-","G7670-","A7671-","A7672-","A7673-","T7674-","T7675-","A7676-","C7677-","A7678-","A7679-","A7680-","C7681-","G7682-","C7683-","T7684-","A7685-","C7686-","A7687-","A7688-","C7689-","A7690-","G7691-","A7692-","T7693-","A7694-","T7695-","T7696-","C7697-","C7698-","A7699-","G7700-","C7701-","T7702-","A7703-","T7704-","C7705-","A7706-","G7707-","A7708-","T7709-","T7710-","A7711-","T7712-","G7713-","T7714-","G7715-","G7716-","T7717-","C7718-","C7719-","A7720-","G7721-","A7722-","G7723-","G7724-","G7725-","A7726-","G7727-","A7728-","T7729-","G7730-","G7731-","A7732-","T7733-","A7734-","T7735-","T7736-","G7737-","T7738-","T7739-","T7740-","A7741-","C7742-","A7743-","C7744-","G7745-","G7746-","T7747-","G7748-","A7749-","C7750-","T7751-","G7752-","T7753-","A7754-","T7755-","C7756-","C7757-","A7758-","C7759-","G7760-","C7761-","T7762-","A7763-","G7764-","A7765-","G7766-","A7767-","T7768-","A7769-","T7770-","C7771-","G7772-","A7773-","C7774-","G7775-","G7776-","T7777-","A7778-","T7779-","G7780-","T7781-","A7782-","T7783-","T7784-","G7785-","T7786-","A7787-","G7788-","A7789-","T7790-","G7791-","C7792-","T7793-","C7794-","T7795-","C7796-","A7797-","T7798-","G7799-","G7800-","T7801-","T7802-","A7803-","T7804-","A7805-","C7806-","A7807-","G7808-","G7809-","T7810-","A7811-","T7812-","T7813-","A7814-","G7815-","A7816-","T7817-","G7818-","T7819-","C7820-","A7821-","G7822-","C7823-","A7824-","T7825-","G7826-","T7827-","A7828-","G7829-","T7830-","A7831-","T7832-","T7833-","A7834-","G7835-","T7836-","A7837-","G7838-","A7839-","C7840-","T7841-","A7842-","T7843-","C7844-","A7845-","A7846-","C7847-","G7848-","T7849-","T7850-","C7851-","A7852-","G7853-","G7854-","A7855-","A7856-","A7857-","A7858-","C7859-","C7860-","A7861-","G7862-","A7863-","C7864-","A7865-","C7866-","T7867-","A7868-","C7869-","A7870-","A7871-","C7872-","A7873-","T7874-","C7875-","A7876-","T7877-","A7878-","T7879-","A7880-","T7881-","C7882-","C7883-","C7884-","A7885-","T7886-","C7887-","T7888-","C7889-","T7890-","A7891-","G7892-","G7893-","T7894-","A7895-","T7896-","T7897-","G7898-","T7899-","G7900-","C7901-","T7902-","T7903-","G7904-","T7905-","A7906-","T7907-","T7908-","A7909-","G7910-","T7911-","A7912-","G7913-","G7914-","C7915-","A7916-","T7917-","T7918-","A7919-","T7920-","T7921-","A7922-","T7923-","T7924-","A7925-","C7926-","G7927-","T7928-","G7929-","T7930-","T7931-","G7932-","T7933-","C7934-","T7935-","A7936-","T7937-","T7938-","A7939-","T7940-","C7941-","T7942-","G7943-","T7944-","T7945-","T7946-","A7947-","T7948-","A7949-","T7950-","G7951-","T7952-","T7953-","C7954-","A7955-","C7956-","T7957-","C7958-","G7959-","A7960-","A7961-","G7962-","A7963-","A7964-","C7965-","T7966-","A7967-","A7968-","A7969-","C7970-","T7971-","A7972-","C7973-","C7974-","T7975-","A7976-","T7977-","A7978-","C7979-","A7980-","A7981-","G7982-","A7983-","T7984-","A7985-","T7986-","G7987-","G7988-","T7989-","T7990-","G7991-","T7992-","G7993-","T7994-","T7995-","A7996-","T7997-","A7998-","T7999-","T8000-","T8001-","T8002-","T8003-","T8004-","A8005-","T8006-","A8007-","A8008-","A8009-","A8010-","T8011-","T8012-","T8013-","T8014-","T8015-","T8016-","T8017-","A8018-","T8019-","G8020-","A8021-","G8022-","T8023-","A8024-","T8025-","T8026-","T8027-","T8028-","T8029-","A8030-","C8031-","A8032-","A8033-","A8034-","A8035-","A8036-","T8037-","G8038-","T8039-","A8040-","T8041-","A8042-","T8043-","G8044-","T8045-","A8046-","T8047-","A8048-","A8049-","A8050-","A8051-","A8052-","A8053-","A8054-","A8055-","T8056-","A8057-","C8058-","T8059-","A8060-","A8061-","G8062-","T8063-","A8064-","T8065-","A8066-","C8067-","G8068-","A8069-","T8070-","G8071-","T8072-","A8073-","T8074-","C8075-","C8076-","T8077-","G8078-","T8079-","A8080-","T8081-","T8082-","A8083-","T8084-","T8085-","T8086-","G8087-","T8088-","A8089-","T8090-","T8091-","T8092-","A8093-","T8094-","C8095-","T8096-","A8097-","A8098-","A8099-","C8100-","A8101-","A8102-","T8103-","A8104-","C8105-","T8106-","T8107-","C8108-","T8109-","G8110-","C8111-","C8112-","T8113-","C8114-","T8115-","A8116-","G8117-","A8118-","T8119-","G8120-","G8121-","G8122-","A8123-","T8124-","A8125-","C8126-","A8127-","A8128-","A8129-","A8130-","A8131-","T8132-","T8133-","T8134-","T8135-","T8136-","T8137-","A8138-","T8139-","T8140-","T8141-","C8142-","A8143-","G8144-","C8145-","A8146-","T8147-","A8148-","T8149-","T8150-","A8151-","A8152-","A8153-","G8154-","T8155-","A8156-","A8157-","A8158-","A8159-","T8160-","C8161-","T8162-","A8163-","G8164-","T8165-","T8166-","A8167-","C8168-","C8169-","T8170-","T8171-","G8172-","A8173-","A8174-","A8175-","A8176-","T8177-","G8178-","A8179-","A8180-","T8181-","A8182-","C8183-","A8184-","G8185-","T8186-","G8187-","G8188-","G8189-","T8190-","G8191-","G8192-","T8193-","T8194-","C8195-","C8196-","G8197-","T8198-","A8199-","T8200-","C8201-","A8202-","C8203-","C8204-","A8205-","G8206-","T8207-","A8208-","A8209-","G8210-","A8211-","A8212-","C8213-","A8214-","T8215-","A8216-","A8217-","T8218-","A8219-","G8220-","T8221-","C8222-","G8223-","A8224-","A8225-","T8226-","A8227-","C8228-","A8229-","G8230-","T8231-","A8232-","T8233-","C8234-","C8235-","G8236-","A8237-","T8238-","T8239-","G8240-","A8241-","G8242-","A8243-","T8244-","T8245-","T8246-","T8247-","G8248-","C8249-","A8250-","T8251-","A8252-","C8253-","A8254-","A8255-","T8256-","A8257-","C8258-","T8259-","A8260-","G8261-","T8262-","C8263-","T8264-","A8265-","G8266-","A8267-","A8268-","A8269-","G8270-","A8271-","A8272-","A8273-","T8274-","T8275-","T8276-","G8277-","T8278-","A8279-","A8280-","T8281-","C8282-","A8283-","T8284-","C8285-","C8286-","T8287-","C8288-","T8289-","G8290-","T8291-","G8292-","A8293-","C8294-","A8295-","G8296-","G8297-","A8298-","G8299-","T8300-","C8301-","C8302-","A8303-","T8304-","A8305-","T8306-","A8307-","T8308-","C8309-","T8310-","G8311-","T8312-","A8313-","T8314-","C8315-","A8316-","T8317-","C8318-","G8319-","T8320-","C8321-","T8322-","A8323-","G8324-","T8325-","T8326-","T8327-","T8328-","T8329-","A8330-","T8331-","C8332-","A8333-","G8334-","T8335-","G8336-","T8337-","C8338-","C8339-","T8340-","A8341-","T8342-","G8343-","C8344-","T8345-","A8346-","T8347-","A8348-","T8349-","T8350-","C8351-","C8352-","T8353-","G8354-","T8355-","T8356-","A8357-","T8358-","C8359-","A8360-","T8361-","C8362-","A8363-","T8364-","T8365-","A8366-","G8367-","T8368-","T8369-","A8370-","A8371-","T8372-","G8373-","A8374-","A8375-","A8376-","A8377-","T8378-","A8379-","A8380-","C8381-","T8382-","C8383-","T8384-","C8385-","G8386-","T8387-","G8388-","C8389-","T8390-","T8391-","C8392-","A8393-","G8394-","A8395-","A8396-","A8397-","A8398-","G8399-","T8400-","C8401-","A8402-","A8403-","A8404-","T8405-","A8406-","T8407-","T8408-","G8409-","T8410-","A8411-","T8412-","C8413-","C8414-","A8415-","T8416-","A8417-","C8418-","A8419-","T8420-","A8421-","T8422-","A8423-","T8424-","C8425-","T8426-","C8427-","C8428-","A8429-","A8430-","A8431-","A8432-","C8433-","T8434-","A8435-","T8436-","C8437-","A8438-","C8439-","T8440-","T8441-","A8442-","T8443-","A8444-","C8445-","G8446-","T8447-","T8448-","T8449-","A8450-","T8451-","C8452-","T8453-","T8454-","T8455-","A8456-","A8457-","C8458-","G8459-","A8460-","A8461-","C8462-","A8463-","T8464-","A8465-","T8466-","A8467-","C8468-","C8469-","T8470-","A8471-","G8472-","A8473-","T8474-","G8475-","G8476-","T8477-","T8478-","A8479-","T8480-","T8481-","T8482-","A8483-","C8484-","T8485-","A8486-","A8487-","C8488-","A8489-","G8490-","A8491-","C8492-","A8493-","T8494-","T8495-","T8496-","T8497-","T8498-","T8499-","C8500-","A8501-","A8502-","G8503-","A8504-","T8505-","C8506-","T8507-","A8508-","T8509-","T8510-","G8511-","A8512-","C8513-","A8514-","A8515-","T8516-","A8517-","A8518-","C8519-","T8520-","C8521-","C8522-","T8523-","A8524-","T8525-","A8526-","G8527-","T8528-","T8529-","T8530-","C8531-","C8532-","A8533-","C8534-","A8535-","T8536-","C8537-","A8538-","A8539-","C8540-","C8541-","A8542-","A8543-","G8544-","T8545-","A8546-","A8547-","T8548-","G8549-","A8550-","T8551-","C8552-","A8553-","T8554-","C8555-","T8556-","A8557-","T8558-","T8559-","G8560-","T8561-","T8562-","A8563-","T8564-","A8565-","T8566-","A8567-","A8568-","C8569-","A8570-","A8571-","T8572-","A8573-","A8574-","C8575-","A8576-","T8577-","A8578-","A8579-","C8580-","T8581-","C8582-","T8583-","T8584-","T8585-","T8586-","C8587-","C8588-","A8589-","T8590-","T8591-","T8592-","T8593-","T8594-","A8595-","T8596-","C8597-","A8598-","G8599-","T8600-","A8601-","T8602-","C8603-","T8604-","A8605-","T8606-","A8607-","T8608-","C8609-","A8610-","A8611-","C8612-","G8613-","T8614-","C8615-","G8616-","T8617-","T8618-","G8619-","T8620-","A8621-","G8622-","T8623-","G8624-","A8625-","A8626-","T8627-","A8628-","G8629-","T8630-","A8631-","G8632-","T8633-","C8634-","A8635-","T8636-","T8637-","G8638-","A8639-","T8640-","C8641-","T8642-","A8643-","T8644-","T8645-","A8646-","T8647-","A8648-","T8649-","G8650-","A8651-","A8652-","A8653-","C8654-","G8655-","G8656-","A8657-","T8658-","A8659-","T8660-","G8661-","T8662-","C8663-","T8664-","A8665-","G8666-","T8667-","T8668-","A8669-","A8670-","T8671-","A8672-","T8673-","T8674-","T8675-","T8676-","C8677-","T8678-","T8679-","T8680-","G8681-","A8682-","T8683-","T8684-","T8685-","A8686-","A8687-","A8688-","G8689-","T8690-","C8691-","T8692-","A8693-","T8694-","A8695-","G8696-","T8697-","C8698-","T8699-","T8700-","T8701-","A8702-","C8703-","A8704-","A8705-","A8706-","C8707-","A8708-","T8709-","A8710-","A8711-","T8712-","A8713-","T8714-","C8715-","C8716-","T8717-","T8718-","A8719-","T8720-","C8721-","C8722-","G8723-","A8724-","C8725-","T8726-","T8727-","T8728-","A8729-","T8730-","A8731-","T8732-","T8733-","T8734-","C8735-","C8736-","T8737-","G8738-","T8739-","A8740-","G8741-","G8742-","G8743-","T8744-","G8745-","G8746-","C8747-","A8748-","T8749-","A8750-","A8751-","T8752-","T8753-","T8754-","T8755-","A8756-","T8757-","T8758-","C8759-","T8760-","G8761-","C8762-","C8763-","T8764-","C8765-","C8766-","A8767-","C8768-","A8769-","A8770-","T8771-","C8772-","A8773-","G8774-","T8775-","G8776-","T8777-","T8778-","T8779-","C8780-","C8781-","A8782-","A8783-","A8784-","T8785-","A8786-","T8787-","A8788-","T8789-","T8790-","A8791-","C8792-","T8793-","A8794-","G8795-","A8796-","C8797-","A8798-","A8799-","T8800-","A8801-","T8802-","T8803-","C8804-","C8805-","A8806-","T8807-","A8808-","T8809-","A8810-","G8811-","T8812-","T8813-","A8814-","T8815-","T8816-","A8817-","G8818-","T8819-","T8820-","A8821-","A8822-","G8823-","G8824-","G8825-","A8826-","C8827-","C8828-","C8829-","A8830-","A8831-","T8832-","T8833-","A8834-","G8835-","A8836-","A8837-","C8838-","A8839-","C8840-","G8841-","T8842-","A8843-","C8844-","G8845-","C8846-","G8847-","C8848-","T8849-","T8850-","A8851-","T8852-","T8853-","C8854-","A8855-","T8856-","C8857-","A8858-","T8859-","T8860-","T8861-","G8862-","G8863-","A8864-","T8865-","C8866-","G8867-","T8868-","A8869-","T8870-","T8871-","T8872-","C8873-","A8874-","T8875-","A8876-","A8877-","A8878-","A8879-","G8880-","T8881-","T8882-","A8883-","T8884-","T8885-","A8886-","T8887-","G8888-","T8889-","T8890-","A8891-","T8892-","A8893-","G8894-","A8895-","T8896-","G8897-","T8898-","C8899-","A8900-","A8901-","C8902-","A8903-","C8904-","A8905-","T8906-","T8907-","C8908-","T8909-","A8910-","C8911-","A8912-","T8913-","T8914-","T8915-","T8916-","T8917-","T8918-","T8919-","A8920-","A8921-","T8922-","T8923-","G8924-","T8925-","C8926-","T8927-","A8928-","T8929-","A8930-","T8931-","A8932-","G8933-","T8934-","A8935-","T8936-","T8937-","T8938-","T8939-","T8940-","C8941-","T8942-","G8943-","A8944-","T8945-","A8946-","T8947-","T8948-","T8949-","T8950-","C8951-","T8952-","A8953-","T8954-","A8955-","A8956-","T8957-","A8958-","T8959-","C8960-","A8961-","G8962-","A8963-","A8964-","T8965-","T8966-","G8967-","T8968-","C8969-","T8970-","T8971-","C8972-","C8973-","A8974-","T8975-","A8976-","G8977-","G8978-","A8979-","A8980-","G8981-","T8982-","T8983-","G8984-","T8985-","A8986-","T8987-","A8988-","C8989-","T8990-","A8991-","T8992-","T8993-","C8994-","G8995-","G8996-","A8997-","A8998-","T8999-","C9000-","A9001-","G9002-","T9003-","T9004-","A9005-","C9006-","A9007-","T9008-","G9009-","T9010-","T9011-","T9012-","A9013-","A9014-","A9015-","T9016-","A9017-","A9018-","T9019-","T9020-","C9021-","T9022-","C9023-","T9024-","G9025-","A9026-","T9027-","G9028-","T9029-","C9030-","A9031-","T9032-","T9033-","C9034-","C9035-","T9036-","T9037-","A9038-","T9039-","A9040-","C9041-","A9042-","A9043-","T9044-","C9045-","A9046-","A9047-","A9048-","T9049-","T9050-","C9051-","A9052-","T9053-","T9054-","A9055-","T9056-","T9057-","A9058-","A9059-","A9060-","C9061-","A9062-","G9063-","T9064-","T9065-","T9066-","A9067-","A9068-","T9069-","A9070-","G9071-","T9072-","C9073-","T9074-","G9075-","T9076-","A9077-","G9078-","A9079-","C9080-","C9081-","T9082-","T9083-","T9084-","A9085-","T9086-","C9087-","G9088-","T9089-","C9090-","G9091-","T9092-","A9093-","C9094-","A9095-","T9096-","A9097-","T9098-","C9099-","C9100-","A9101-","T9102-","T9103-","G9104-","T9105-","C9106-","T9107-","T9108-","A9109-","T9110-","T9111-","A9112-","G9113-","T9114-","T9115-","A9116-","C9117-","G9118-","C9119-","T9120-","T9121-","A9122-","T9123-","T9124-","T9125-","T9126-","T9127-","A9128-","T9129-","G9130-","G9131-","G9132-","T9133-","T9134-","T9135-","T9136-","A9137-","C9138-","G9139-","T9140-","T9141-","G9142-","C9143-","T9144-","T9145-","T9146-","A9147-","T9148-","T9149-","A9150-","T9151-","A9152-","T9153-","T9154-","T9155-","T9156-","A9157-","T9158-","A9159-","A9160-","T9161-","A9162-","A9163-","T9164-","G9165-","A9166-","T9167-","T9168-","G9169-","T9170-","T9171-","T9172-","G9173-","A9174-","C9175-","A9176-","A9177-","T9178-","G9179-","T9180-","C9181-","G9182-","T9183-","A9184-","G9185-","T9186-","A9187-","T9188-","A9189-","G9190-","A9191-","T9192-","A9193-","T9194-","A9195-","T9196-","T9197-","A9198-","T9199-","T9200-","A9201-","G9202-","A9203-","G9204-","G9205-","A9206-","G9207-","G9208-","T9209-","A9210-","T9211-","A9212-","A9213-","T9214-","T9215-","A9216-","T9217-","A9218-","A9219-","A9220-","A9221-","A9222-","G9223-","T9224-","T9225-","T9226-","C9227-","T9228-","G9229-","A9230-","G9231-","T9232-","A9233-","C9234-","G9235-","A9236-","T9237-","G9238-","T9239-","T9240-","A9241-","T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","C9257-","A9258-","T9259-","T9260-","A9261-","A9262-","C9263-","A9264-","T9265-","C9266-","A9267-","T9268-","A9269-","C9270-","A9271-","T9272-","C9273-","A9274-","A9275-","T9276-","T9277-","A9278-","A9279-","C9280-","T9281-","A9282-","C9283-","A9284-","T9285-","T9286-","C9287-","T9288-","T9289-","A9290-","T9291-","A9292-","A9293-","C9294-","A9295-","T9296-","T9297-","G9298-","T9299-","A9300-","A9301-","T9302-","C9303-","A9304-","A9305-","A9306-","A9307-","G9308-","A9309-","A9310-","T9311-","T9312-","G9313-","C9314-","A9315-","A9316-","T9317-","T9318-","T9319-","T9320-","G9321-","A9322-","T9323-","G9324-","T9325-","A9326-","T9327-","A9328-","A9329-","C9330-","A9331-","A9332-","C9333-","T9334-","G9335-","T9336-","C9337-","A9338-","A9339-","T9340-","G9341-","G9342-","A9343-","A9344-","T9345-","T9346-","G9347-","T9348-","A9349-","T9350-","A9351-","T9352-","T9353-","A9354-","C9355-","A9356-","A9357-","A9358-","T9359-","T9360-","A9361-","C9362-","G9363-","G9364-","T9365-","A9366-","T9367-","G9368-","T9369-","T9370-","G9371-","T9372-","A9373-","A9374-","C9375-","A9376-","A9377-","C9378-","A9379-","A9380-","A9381-","T9382-","A9383-","C9384-","C9385-","G9386-","A9387-","T9388-","C9389-","G9390-","G9391-","T9392-","A9393-","A9394-","T9395-","T9396-","G9397-","T9398-","C9399-","T9400-","C9401-","T9402-","G9403-","C9404-","C9405-","G9406-","C9407-","T9408-","G9409-","T9410-","A9411-","A9412-","T9413-","A9414-","G9415-","A9416-","A9417-","T9418-","T9419-","A9420-","A9421-","T9422-","T9423-","A9424-","T9425-","A9426-","T9427-","A9428-","T9429-","C9430-","T9431-","A9432-","T9433-","T9434-","A9435-","C9436-","A9437-","C9438-","C9439-","G9440-","G9441-","C9442-","C9443-","T9444-","T9445-","G9446-","T9447-","A9448-","T9449-","C9450-","A9451-","T9452-","A9453-","A9454-","T9455-","A9456-","A9457-","A9458-","G9459-","T9460-","T9461-","G9462-","T9463-","G9464-","G9465-","T9466-","A9467-","G9468-","T9469-","A9470-","T9471-","G9472-","A9473-","T9474-","C9475-","T9476-","C9477-","C9478-","A9479-","T9480-","A9481-","T9482-","T9483-","T9484-","A9485-","T9486-","A9487-","A9488-","T9489-","T9490-","T9491-","A9492-","G9493-","T9494-","A9495-","C9496-","T9497-","T9498-","T9499-","G9500-","T9501-","A9502-","T9503-","T9504-","T9505-","A9506-","G9507-","T9508-","T9509-","T9510-","T9511-","T9512-","T9513-","T9514-","G9515-","G9516-","A9517-","A9518-","T9519-","C9520-","A9521-","T9522-","A9523-","A9524-","A9525-","A9526-","A9527-","A9528-","A9529-","G9530-","T9531-","T9532-","T9533-","T9534-","A9535-","C9536-","T9537-","A9538-","A9539-","T9540-","T9541-","T9542-","A9543-","A9544-","A9545-","A9546-","T9547-","T9548-","T9549-","A9550-","A9551-","A9552-","A9553-","A9554-","G9555-","T9556-","A9557-","T9558-","T9559-","T9560-","A9561-","C9562-","A9563-","T9564-","T9565-","T9566-","T9567-","T9568-","C9569-","A9570-","C9571-","T9572-","G9573-","T9574-","T9575-","T9576-","A9577-","G9578-","T9579-","C9580-","G9581-","C9582-","G9583-","G9584-","A9585-","T9586-","A9587-","T9588-","G9589-","G9590-","A9591-","A9592-","T9593-","T9594-","C9595-","G9596-","A9597-","T9598-","C9599-","C9600-","T9601-","G9602-","T9603-","C9604-","A9605-","A9606-","A9607-","A9608-","T9609-","C9610-","A9611-","A9612-","T9613-","A9614-","C9615-","A9616-","T9617-","C9618-","A9619-","T9620-","C9621-","T9622-","A9623-","T9624-","A9625-","G9626-","A9627-","T9628-","C9629-","A9630-","T9631-","G9632-","T9633-","A9634-","A9635-","C9636-","A9637-","A9638-","T9639-","A9640-","T9641-","T9642-","A9643-","C9644-","A9645-","A9646-","T9647-","A9648-","C9649-","A9650-","T9651-","A9652-","G9653-","A9654-","T9655-","G9656-","A9657-","A9658-","C9659-","C9660-","A9661-","A9662-","A9663-","T9664-","G9665-","A9666-","T9667-","A9668-","T9669-","A9670-","A9671-","G9672-","A9673-","C9674-","T9675-","A9676-","A9677-","C9678-","A9679-","G9680-","T9681-","A9682-","T9683-","G9684-","C9685-","A9686-","T9687-","T9688-","A9689-","T9690-","C9691-","C9692-","G9693-","A9694-","A9695-","A9696-","T9697-","G9698-","T9699-","T9700-","A9701-","A9702-","T9703-","A9704-","A9705-","C9706-","A9707-","T9708-","T9709-","A9710-","C9711-","A9712-","T9713-","A9714-","T9715-","T9716-","A9717-","T9718-","A9719-","T9720-","C9721-","A9722-","A9723-","T9724-","A9725-","T9726-","C9727-","A9728-","C9729-","A9730-","A9731-","A9732-","A9733-","A9734-","T9735-","A9736-","A9737-","A9738-","T9739-","C9740-","C9741-","A9742-","C9743-","A9744-","T9745-","T9746-","T9747-","G9748-","G9749-","C9750-","T9751-","A9752-","A9753-","T9754-","C9755-","G9756-","A9757-","T9758-","T9759-","T9760-","C9761-","G9762-","G9763-","G9764-","C9765-","T9766-","T9767-","G9768-","G9769-","A9770-","A9771-","A9772-","A9773-","A9774-","A9775-","C9776-","G9777-","T9778-","A9779-","T9780-","C9781-","G9782-","C9783-","C9784-","G9785-","G9786-","A9787-","A9788-","G9789-","G9790-","G9791-","A9792-","C9793-","T9794-","A9795-","T9796-","A9797-","T9798-","G9799-","A9800-","C9801-","T9802-","A9803-","A9804-","C9805-","T9806-","T9807-","A9808-","T9809-","C9810-","T9811-","A9812-","G9813-","A9814-","G9815-","A9816-","T9817-","A9818-","C9819-","A9820-","G9821-","G9822-","A9823-","A9824-","T9825-","A9826-","C9827-","A9828-","A9829-","C9830-","A9831-","A9832-","T9833-","C9834-","A9835-","A9836-","A9837-","A9838-","C9839-","T9840-","T9841-","A9842-","C9843-","T9844-","G9845-","A9846-","A9847-","A9848-","C9849-","T9850-","A9851-","T9852-","A9853-","C9854-","G9855-","T9856-","A9857-","A9858-","C9859-","T9860-","G9861-","T9862-","C9863-","A9864-","A9865-","A9866-","A9867-","A9868-","A9869-","A9870-","T9871-","A9872-","A9873-","A9874-","A9875-","A9876-","C9877-","A9878-","T9879-","A9880-","T9881-","A9882-","T9883-","G9884-","G9885-","T9886-","C9887-","T9888-","A9889-","T9890-","A9891-","T9892-","A9893-","T9894-","A9895-","C9896-","A9897-","C9898-","T9899-","A9900-","C9901-","A9902-","A9903-","T9904-","T9905-","T9906-","A9907-","G9908-","T9909-","T9910-","A9911-","T9912-","T9913-","A9914-","A9915-","T9916-","G9917-","T9918-","G9919-","G9920-","T9921-","T9922-","A9923-","T9924-","T9925-","G9926-","A9927-","T9928-","T9929-","G9930-","G9931-","A9932-","T9933-","A9934-","A9935-","C9936-","C9937-","G9938-","A9939-","T9940-","G9941-","T9942-","G9943-","A9944-","T9945-","T9946-","G9947-","T9948-","T9949-","C9950-","A9951-","A9952-","T9953-","C9954-","A9955-","A9956-","T9957-","A9958-","T9959-","T9960-","A9961-","A9962-","G9963-","A9964-","G9965-","G9966-","G9967-","T9968-","T9969-","G9970-","G9971-","T9972-","A9973-","A9974-","A9975-","T9976-","T9977-","G9978-","G9979-","T9980-","A9981-","C9982-","A9983-","T9984-","A9985-","G9986-","C9987-","T9988-","A9989-","A9990-","T9991-","A9992-","A9993-","T9994-","A9995-","C9996-","A9997-","T9998-","A9999-","T10000-","A10001-","C10002-","T10003-","C10004-","C10005-","A10006-","A10007-","A10008-","T10009-","A10010-","C10011-","A10012-","C10013-","C10014-","C10015-","A10016-","A10017-","T10018-","A10019-","A10020-","T10021-","A10022-","C10023-","T10024-","A10025-","C10026-","A10027-","A10028-","C10029-","C10030-","A10031-","T10032-","T10033-","T10034-","C10035-","T10036-","G10037-","A10038-","G10039-","T10040-","T10041-","G10042-","G10043-","A10044-","T10045-","A10046-","T10047-","C10048-","A10049-","T10050-","C10051-","A10052-","A10053-","A10054-","A10055-","T10056-","A10057-","C10058-","T10059-","G10060-","G10061-","A10062-","T10063-","A10064-","A10065-","A10066-","T10067-","A10068-","C10069-","G10070-","A10071-","G10072-","G10073-","A10074-","C10075-","A10076-","T10077-","G10078-","T10079-","A10080-","T10081-","A10082-","G10083-","A10084-","G10085-","T10086-","A10087-","A10088-","G10089-","T10090-","A10091-","A10092-","A10093-","G10094-","A10095-","A10096-","A10097-","A10098-","A10099-","G10100-","A10101-","A10102-","T10103-","G10104-","T10105-","G10106-","G10107-","A10108-","A10109-","T10110-","T10111-","T10112-","G10113-","C10114-","T10115-","A10116-","T10117-","G10118-","A10119-","A10120-","G10121-","T10122-","T10123-","G10124-","T10125-","T10126-","T10127-","A10128-","C10129-","T10130-","C10131-","A10132-","A10133-","A10134-","A10135-","C10136-","G10137-","A10138-","T10139-","T10140-","A10141-","G10142-","A10143-","A10144-","A10145-","A10146-","C10147-","G10148-","A10149-","T10150-","A10151-","G10152-","A10153-","T10154-","A10155-","C10156-","T10157-","T10158-","T10159-","G10160-","G10161-","T10162-","T10163-","T10164-","A10165-","T10166-","T10167-","G10168-","G10169-","A10170-","T10171-","T10172-","C10173-","G10174-","T10175-","G10176-","T10177-","A10178-","A10179-","T10180-","C10181-","A10182-","T10183-","A10184-","T10185-","A10186-","T10187-","T10188-","T10189-","T10190-","G10191-","C10192-","A10193-","T10194-","A10195-","A10196-","C10197-","A10198-","T10199-","G10200-","T10201-","A10202-","T10203-","C10204-","A10205-","A10206-","T10207-","A10208-","T10209-","A10210-","T10211-","G10212-","G10213-","C10214-","A10215-","T10216-","A10217-","G10218-","A10219-","A10220-","C10221-","A10222-","C10223-","G10224-","A10225-","A10226-","G10227-","A10228-","G10229-","A10230-","A10231-","A10232-","C10233-","C10234-","G10235-","G10236-","T10237-","G10238-","C10239-","G10240-","T10241-","C10242-","A10243-","G10244-","A10245-","T10246-","A10247-","A10248-","T10249-","T10250-","G10251-","T10252-","C10253-","C10254-","T10255-","A10256-","T10257-","A10258-","T10259-","G10260-","C10261-","C10262-","G10263-","T10264-","A10265-","C10266-","A10267-","C10268-","G10269-","T10270-","T10271-","T10272-","T10273-","A10274-","A10275-","A10276-","A10277-","A10278-","A10279-","A10280-","T10281-","A10282-","A10283-","C10284-","A10285-","A10286-","T10287-","G10288-","A10289-","G10290-","C10291-","A10292-","A10293-","G10294-","T10295-","T10296-","C10297-","T10298-","A10299-","T10300-","A10301-","A10302-","G10303-","C10304-","T10305-","A10306-","G10307-","T10308-","T10309-","A10310-","A10311-","C10312-","T10313-","A10314-","A10315-","T10316-","A10317-","A10318-","A10319-","T10320-","A10321-","A10322-","A10323-","A10324-","A10325-","G10326-","T10327-","T10328-","T10329-","A10330-","A10331-","T10332-","T10333-","A10334-","T10335-","C10336-","G10337-","A10338-","C10339-","G10340-","A10341-","T10342-","A10343-","T10344-","A10345-","T10346-","G10347-","T10348-","C10349-","G10350-","T10351-","T10352-","A10353-","T10354-","T10355-","T10356-","T10357-","T10358-","C10359-","T10360-","C10361-","T10362-","C10363-","A10364-","T10365-","A10366-","T10367-","G10368-","A10369-","A10370-","A10371-","G10372-","A10373-","T10374-","T10375-","A10376-","A10377-","T10378-","T10379-","T10380-","G10381-","A10382-","T10383-","T10384-","C10385-","T10386-","A10387-","A10388-","T10389-","A10390-","T10391-","A10392-","A10393-","T10394-","C10395-","T10396-","T10397-","C10398-","A10399-","G10400-","T10401-","A10402-","T10403-","T10404-","G10405-","G10406-","A10407-","T10408-","G10409-","A10410-","A10411-","T10412-","C10413-","T10414-","C10415-","A10416-","A10417-","T10418-","T10419-","C10420-","A10421-","A10422-","A10423-","T10424-","T10425-","A10426-","A10427-","T10428-","T10429-","C10430-","C10431-","A10432-","T10433-","T10434-","A10435-","G10436-","A10437-","T10438-","T10439-","A10440-","G10441-","A10442-","T10443-","T10444-","A10445-","G10446-","A10447-","T10448-","T10449-","A10450-","G10451-","A10452-","T10453-","C10454-","A10455-","T10456-","A10457-","A10458-","A10459-","T10460-","A10461-","A10462-","A10463-","A10464-","A10465-","T10466-","A10467-","G10468-","T10469-","A10470-","G10471-","C10472-","A10473-","C10474-","G10475-","C10476-","A10477-","C10478-","T10479-","A10480-","C10481-","T10482-","T10483-","C10484-","A10485-","G10486-","C10487-","C10488-","A10489-","A10490-","A10491-","T10492-","A10493-","T10494-","T10495-","C10496-","T10497-","T10498-","T10499-","T10500-","T10501-","T10502-","G10503-","A10504-","A10505-","A10506-","C10507-","G10508-","C10509-","C10510-","A10511-","T10512-","C10513-","T10514-","A10515-","G10516-","C10517-","G10518-","T10519-","A10520-","A10521-","T10522-","G10523-","A10524-","G10525-","A10526-","A10527-","C10528-","A10529-","C10530-","A10531-","A10532-","G10533-","T10534-","G10535-","A10536-","A10537-","C10538-","C10539-","T10540-","A10541-","T10542-","A10543-","A10544-","T10545-","G10546-","A10547-","G10548-","C10549-","A10550-","A10551-","A10552-","T10553-","T10554-","T10555-","A10556-","T10557-","T10558-","A10559-","G10560-","T10561-","A10562-","T10563-","C10564-","G10565-","G10566-","T10567-","T10568-","A10569-","C10570-","A10571-","T10572-","G10573-","A10574-","A10575-","G10576-","G10577-","A10578-","C10579-","T10580-","T10581-","T10582-","A10583-","C10584-","G10585-","T10586-","A10587-","G10588-","A10589-","G10590-","T10591-","G10592-","G10593-","T10594-","G10595-","A10596-","T10597-","T10598-","C10599-","C10600-","T10601-","C10602-","C10603-","A10604-","T10605-","C10606-","T10607-","G10608-","T10609-","G10610-","G10611-","T10612-","A10613-","C10614-","G10615-","A10616-","A10617-","C10618-","G10619-","G10620-","T10621-","T10622-","T10623-","C10624-","A10625-","T10626-","C10627-","T10628-","T10629-","C10630-","T10631-","T10632-","T10633-","G10634-","A10635-","T10636-","G10637-","C10638-","C10639-","A10640-","C10641-","C10642-","A10643-","C10644-","C10645-","C10646-","A10647-","G10648-","A10649-","T10650-","G10651-","T10652-","T10653-","C10654-","T10655-","A10656-","T10657-","A10658-","A10659-","A10660-","C10661-","T10662-","T10663-","G10664-","G10665-","T10666-","A10667-","T10668-","C10669-","C10670-","T10671-","C10672-","G10673-","T10674-","C10675-","C10676-","G10677-","A10678-","T10679-","T10680-","T10681-","C10682-","A10683-","T10684-","A10685-","T10686-","C10687-","A10688-","T10689-","T10690-","T10691-","G10692-","C10693-","C10694-","A10695-","A10696-","C10697-","C10698-","A10699-","A10700-","T10701-","A10702-","C10703-","A10704-","T10705-","A10706-","T10707-","A10708-","G10709-","C10710-","T10711-","A10712-","A10713-","A10714-","C10715-","C10716-","C10717-","A10718-","G10719-","G10720-","C10721-","A10722-","T10723-","A10724-","C10725-","G10726-","T10727-","T10728-","C10729-","C10730-","A10731-","C10732-","A10733-","C10734-","A10735-","T10736-","C10737-","C10738-","G10739-","G10740-","A10741-","A10742-","C10743-","A10744-","A10745-","T10746-","G10747-","A10748-","A10749-","A10750-","T10751-","T10752-","C10753-","T10754-","C10755-","C10756-","A10757-","G10758-","A10759-","A10760-","G10761-","A10762-","T10763-","G10764-","T10765-","T10766-","A10767-","C10768-","A10769-","A10770-","T10771-","G10772-","G10773-","C10774-","T10775-","A10776-","G10777-","A10778-","T10779-","T10780-","T10781-","G10782-","G10783-","A10784-","C10785-","A10786-","T10787-","T10788-","T10789-","G10790-","G10791-","T10792-","T10793-","T10794-","C10795-","A10796-","A10797-","C10798-","C10799-","G10800-","C10801-","G10802-","T10803-","T10804-","A10805-","A10806-","C10807-","A10808-","T10809-","A10810-","T10811-","G10812-","A10813-","G10814-","T10815-","G10816-","A10817-","A10818-","C10819-","A10820-","C10821-","A10822-","C10823-","C10824-","C10825-","A10826-","T10827-","A10828-","C10829-","A10830-","T10831-","G10832-","A10833-","A10834-","A10835-","G10836-","C10837-","G10838-","A10839-","T10840-","G10841-","A10842-","G10843-","A10844-","A10845-","A10846-","T10847-","A10848-","G10849-","G10850-","A10851-","T10852-","T10853-","C10854-","T10855-","C10856-","A10857-","T10858-","C10859-","T10860-","T10861-","G10862-","C10863-","C10864-","A10865-","A10866-","A10867-","A10868-","T10869-","A10870-","T10871-","C10872-","A10873-","C10874-","T10875-","A10876-","T10877-","A10878-","A10879-","A10880-","A10881-","A10882-","A10883-","T10884-","T10885-","T10886-","A10887-","T10888-","T10889-","T10890-","A10891-","T10892-","C10893-","A10894-","A10895-","T10896-","T10897-","T10898-","T10899-","A10900-","A10901-","A10902-","G10903-","G10904-","T10905-","A10906-","T10907-","A10908-","A10909-","A10910-","A10911-","A10912-","A10913-","A10914-","T10915-","A10916-","C10917-","T10918-","T10919-","A10920-","T10921-","T10922-","G10923-","T10924-","T10925-","G10926-","C10927-","T10928-","C10929-","G10930-","A10931-","A10932-","T10933-","A10934-","T10935-","T10936-","T10937-","T10938-","G10939-","T10940-","A10941-","T10942-","T10943-","T10944-","G10945-","A10946-","T10947-","G10948-","G10949-","T10950-","A10951-","T10952-","A10953-","C10954-","G10955-","G10956-","A10957-","A10958-","G10959-","A10960-","T10961-","T10962-","A10963-","G10964-","A10965-","A10966-","A10967-","T10968-","G10969-","T10970-","A10971-","G10972-","G10973-","T10974-","A10975-","T10976-","T10977-","A10978-","T10979-","C10980-","A10981-","T10982-","C10983-","A10984-","A10985-","C10986-","T10987-","G10988-","A10989-","T10990-","T10991-","T10992-","T10993-","A10994-","T10995-","G10996-","A10997-","T10998-","G10999-","G11000-","T11001-","T11002-","T11003-","T11004-","A11005-","T11006-","G11007-","A11008-","A11009-","T11010-","T11011-","T11012-","T11013-","A11014-","T11015-","T11016-","A11017-","T11018-","G11019-","C11020-","T11021-","T11022-","C11023-","A11024-","C11025-","T11026-","A11027-","T11028-","T11029-","G11030-","C11031-","A11032-","T11033-","C11034-","G11035-","G11036-","A11037-","A11038-","A11039-","T11040-","A11041-","A11042-","T11043-","A11044-","T11045-","C11046-","A11047-","T11048-","A11049-","T11050-","G11051-","C11052-","T11053-","T11054-","C11055-","C11056-","A11057-","C11058-","G11059-","T11060-","A11061-","T11062-","A11063-","T11064-","T11065-","T11066-","T11067-","A11068-","T11069-","T11070-","T11071-","T11072-","G11073-","T11074-","T11075-","T11076-","T11077-","G11078-","A11079-","C11080-","T11081-","C11082-","A11083-","T11084-","A11085-","A11086-","T11087-","A11088-","C11089-","G11090-","C11091-","A11092-","C11093-","G11094-","T11095-","A11096-","A11097-","T11098-","T11099-","C11100-","T11101-","G11102-","G11103-","A11104-","T11105-","T11106-","A11107-","T11108-","T11109-","G11110-","G11111-","C11112-","A11113-","T11114-","A11115-","T11116-","C11117-","G11118-","A11119-","T11120-","G11121-","A11122-","A11123-","T11124-","A11125-","A11126-","T11127-","T11128-","T11129-","T11130-","A11131-","G11132-","C11133-","T11134-","C11135-","C11136-","A11137-","T11138-","G11139-","C11140-","T11141-","C11142-","A11143-","G11144-","T11145-","A11146-","A11147-","A11148-","T11149-","A11150-","T11151-","T11152-","A11153-","A11154-","T11155-","G11156-","A11157-","G11158-","A11159-","A11160-","C11161-","A11162-","T11163-","A11164-","G11165-","T11166-","G11167-","T11168-","T11169-","G11170-","C11171-","C11172-","T11173-","C11174-","C11175-","T11176-","A11177-","C11178-","C11179-","A11180-","T11181-","T11182-","A11183-","T11184-","T11185-","T11186-","T11187-","T11188-","T11189-","T11190-","C11191-","A11192-","T11193-","C11194-","T11195-","C11196-","A11197-","T11198-","T11199-","C11200-","A11201-","A11202-","T11203-","T11204-","C11205-","T11206-","T11207-","G11208-","A11209-","T11210-","T11211-","G11212-","C11213-","A11214-","G11215-","A11216-","G11217-","A11218-","T11219-","C11220-","T11221-","A11222-","T11223-","A11224-","T11225-","A11226-","A11227-","T11228-","C11229-","A11230-","T11231-","T11232-","A11233-","T11234-","A11235-","G11236-","C11237-","G11238-","T11239-","T11240-","G11241-","A11242-","C11243-","T11244-","T11245-","A11246-","T11247-","G11248-","G11249-","A11250-","C11251-","T11252-","C11253-","T11254-","G11255-","G11256-","A11257-","A11258-","T11259-","C11260-","T11261-","T11262-","A11263-","G11264-","A11265-","C11266-","G11267-","A11268-","T11269-","G11270-","T11271-","A11272-","C11273-","A11274-","G11275-","T11276-","C11277-","A11278-","T11279-","C11280-","T11281-","A11282-","T11283-","A11284-","A11285-","T11286-","C11287-","A11288-","T11289-","G11290-","G11291-","T11292-","A11293-","T11294-","A11295-","T11296-","T11297-","T11298-","A11299-","A11300-","T11301-","A11302-","C11303-","A11304-","T11305-","T11306-","G11307-","T11308-","T11309-","T11310-","T11311-","A11312-","T11313-","A11314-","G11315-","C11316-","A11317-","T11318-","A11319-","G11320-","G11321-","C11322-","A11323-","T11324-","T11325-","A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","C11727T","C39139T","-173314A","-173315T","-173316A","-173317T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A185259-","G185260-","A185261-","A185262-","T185263-","G185264-","T185265-","T185266-","T185267-","G185268-","C185269-","C185270-","A185271-","C185272-","A185273-","T185274-","T185275-","G185276-","G185277-","C185278-","T185279-","A185280-","G185281-","A185282-","G185283-","G185284-","A185285-","A185286-","T185287-","G185288-","C185289-","C185290-","G185291-","T185292-","T185293-","T185294-","A185295-","G185296-","A185297-","T185298-","C185299-","A185300-","A185301-","C185302-","G185303-","T185304-","A185305-","T185306-","T185307-","G185308-","C185309-","G185310-","A185311-","T185312-","A185313-","A185314-","C185315-","A185316-","G185317-","A185318-","C185319-","G185320-","A185321-","C185322-","G185323-","A185324-","T185325-","C185326-","A185327-","G185328-","G185329-","T185330-","T185331-","G185332-","T185333-","T185334-","A185335-","T185336-","T185337-","A185338-","T185339-","G185340-","C185341-","A185342-","G185343-","G185344-","A185345-","A185346-","T185347-","A185348-","C185349-","C185350-","A185351-","T185352-","T185353-","T185354-","C185355-","A185356-","T185357-","G185358-","A185359-","A185360-","G185361-","A185362-","T185363-","A185364-","G185365-","T185366-","G185367-","T185368-","A185369-","G185370-","A185371-","A185372-","A185373-","C185374-","A185375-","G185376-","A185377-","T185378-","A185379-","T185380-","A185381-","C185382-","A185383-","T185384-","T185385-","A185386-","T185387-","G185388-","G185389-","A185390-","C185391-","C185392-","A185393-","G185394-","A185395-","A185396-","A185397-","T185398-","A185399-","A185400-","T185401-","G185402-","T185403-","T185404-","A185405-","A185406-","A185407-","G185408-","G185409-","A185410-","A185411-","A185412-","C185413-","A185414-","T185415-","A185416-","T185417-","G185418-","A185419-","C185420-","A185421-","T185422-","A185423-","A185424-","A185425-","C185426-","A185427-","G185428-","T185429-","A185430-","T185431-","T185432-","G185433-","A185434-","C185435-","C185436-","C185437-","A185438-","C185439-","G185440-","A185441-","G185442-","T185443-","T185444-","A185445-","T185446-","A185447-","A185448-","C185449-","A185450-","A185451-","A185452-","G185453-","T185454-","C185455-","A185456-","A185457-","A185458-","G185459-","A185460-","C185461-","C185462-","C185463-","A185464-","T185465-","T185466-","T185467-","T185468-","C185469-","C185470-","T185471-","G185472-","C185473-","T185474-","C185475-","C185476-","A185477-","T185478-","T185479-","G185480-","A185481-","G185482-","T185483-","G185484-","T185485-","A185486-","A185487-","A185488-","A185489-","T185490-","T185491-","C185492-","A185493-","T185494-","G185495-","G185496-","T185497-","T185498-","G185499-","A185500-","C185501-","A185502-","A185503-","T185504-","T185505-","T185506-","A185507-","G185508-","G185509-","A185510-","A185511-","A185512-","T185513-","G185514-","G185515-","A185516-","T185517-","A185518-","T185519-","G185520-","A185521-","C185522-","A185523-","A185524-","C185525-","C185526-","C185527-","T185528-","A185529-","A185530-","T185531-","T185532-","C185533-","A185534-","T185535-","T185536-","T185537-","T185538-","G185539-","G185540-","G185541-","A185542-","A185543-","G185544-","A185545-","T185546-","G185547-","C185548-","T185549-","A185550-","A185551-","A185552-","A185553-","C185554-","T185555-","A185556-","A185557-","G185558-","A185559-","A185560-","A185561-","C185562-","G185563-","G185564-","A185565-","C185566-","A185567-","T185568-","A185569-","T185570-","A185571-","G185572-","T185573-","G185574-","C185575-","A185576-","A185577-","T185578-","G185579-","A185580-","C185581-","G185582-","A185583-","T185584-","A185585-","A185586-","A185587-","A185588-","G185589-","T185590-","C185591-","C185592-","T185593-","A185594-","C185595-","C185596-","A185597-","T185598-","G185599-","T185600-","A185601-","C185602-","A185603-","G185604-","T185605-","G185606-","A185607-","G185608-","A185609-","A185610-","A185611-","T185612-","A185613-","A185614-","A185615-","A185616-","A185617-","T185618-","A185619-","T185620-","A185621-","G185622-","A185623-","C185624-","T185625-","T185626-","T185627-","G185628-","G185629-","A185630-","T185631-","A185632-","T185633-","A185634-","A185635-","C185636-","T185637-","A185638-","T185639-","G185640-","G185641-","A185642-","G185643-","A185644-","T185645-","A185646-","T185647-","T185648-","A185649-","T185650-","T185651-","T185652-","C185653-","T185654-","A185655-","A185656-","T185657-","A185658-","T185659-","G185660-","G185661-","T185662-","T185663-","T185664-","A185665-","T185666-","C185667-","T185668-","A185669-","C185670-","A185671-","A185672-","T185673-","C185674-","T185675-","A185676-","C185677-","T185678-","A185679-","G185680-","T185681-","C185682-","A185683-","G185684-","G185685-","A185686-","T185687-","T185688-","A185689-","T185690-","G185691-","G185692-","A185693-","G185694-","A185695-","T185696-","G185697-","G185698-","T185699-","A185700-","C185701-","C185702-","A185703-","A185704-","A185705-","T185706-","A185707-","T185708-","A185709-","C185710-","A185711-","T185712-","T185713-","T185714-","A185715-","A185716-","A185717-","T185718-","C185719-","C185720-","G185721-","T185722-","A185723-","A185724-","C185725-","T185726-","A185727-","G185728-","A185729-","T185730-","C185731-","A185732-","G185733-","A185734-","T185735-","C185736-","A185737-","T185738-","G185739-","A185740-","G185741-","T185742-","G185743-","T185744-","G185745-","A185746-","A185747-","T185748-","C185749-","T185750-","A185751-","G185752-","C185753-","T185754-","T185755-","A185756-","G185757-","A185758-","T185759-","C185760-","T185761-","A185762-","A185763-","C185764-","G185765-","T185766-","C185767-","T185768-","A185769-","A185770-","G185771-","G185772-","A185773-","A185774-","G185775-","T185776-","A185777-","A185778-","C185779-","T185780-","G185781-","T185782-","G185783-","A185784-","C185785-","A185786-","T185787-","G185788-","T185789-","C185790-","C185791-","T185792-","G185793-","C185794-","G185795-","T185796-","T185797-","T185798-","A185799-","G185800-","T185801-","A185802-","T185803-","A185804-","C185805-","C185806-","A185807-","A185808-","G185809-","A185810-","A185811-","A185812-","T185813-","A185814-","T185815-","A185816-","T185817-","C185818-","A185819-","A185820-","C185821-","A185822-","T185823-","A185824-","T185825-","G185826-","A185827-","A185828-","G185829-","G185830-","T185831-","C185832-","T185833-","A185834-","T185835-","G185836-","C185837-","T185838-","T185839-","T185840-","A185841-","G185842-","T185843-","G185844-","T185845-","T185846-","A185847-","C185848-","T185849-","A185850-","C185851-","A185852-","T185853-","C185854-","T185855-","A185856-","A185857-","A185858-","G185859-","A185860-","T185861-","C185862-","A185863-","T185864-","T185865-","G185866-","T185867-","G185868-","C185869-","T185870-","A185871-","C185872-","A185873-","G185874-","G185875-","T185876-","A185877-","T185878-","T185879-","G185880-","G185881-","T185882-","T185883-","G185884-","G185885-","T185886-","T185887-","A185888-","A185889-","A185890-","A185891-","T185892-","C185893-","T185894-","A185895-","G185896-","T185897-","G185898-","G185899-","T185900-","T185901-","A185902-","T185903-","G185904-","G185905-","G185906-","A185907-","A185908-","G185909-","G185910-","A185911-","A185912-","G185913-","A185914-","T185915-","G185916-","C185917-","T185918-","G185919-","A185920-","T185921-","A185922-","A185923-","A185924-","C185925-","C185926-","A185927-","C185928-","G185929-","T185930-","G185931-","C185932-","T185933-","T185934-","G185935-","T185936-","T185937-","T185938-","T185939-","C185940-","A185941-","T185942-","C185943-","A185944-","T185945-","T185946-","G185947-","G185948-","A185949-","A185950-","T185951-","T185952-","A185953-","T185954-","T185955-","A185956-","C185957-","A185958-","C185959-","A185960-","C185961-","T185962-","G185963-","T185964-","C185965-","G185966-","T185967-","T185968-","G185969-","G185970-","A185971-","T185972-","T185973-","A185974-","T185975-","T185976-","A185977-","C185978-","T185979-","G185980-","T185981-","T185982-","C185983-","A185984-","T185985-","A185986-","C185987-","G185988-","A185989-","A185990-","G185991-","A185992-","T185993-","A185994-","T185995-","T185996-","T185997-","G185998-","G185999-","A186000-","G186001-","A186002-","A186003-","G186004-","C186005-","A186006-","C186007-","C186008-","T186009-","G186010-","G186011-","C186012-","C186013-","T186014-","G186015-","A186016-","C186017-","T186018-","A186019-","T186020-","G186021-","A186022-","T186023-","C186024-","C186025-","A186026-","T186027-","G186028-","T186029-","A186030-","A186031-","G186032-","T186033-","C186034-","A186035-","T186036-","A186037-","T186038-","A186039-","T186040-","C186041-","C186042-","A186043-","T186044-","A186045-","T186046-","A186047-","G186048-","A186049-","G186050-","T186051-","A186052-","T186053-","A186054-","G186055-","A186056-","G186057-","A186058-","T186059-","A186060-","C186061-","A186062-","T186063-","G186064-","G186065-","A186066-","T186067-","A186068-","G186069-","A186070-","A186071-","T186072-","C186073-","T186074-","A186075-","A186076-","T186077-","G186078-","T186079-","G186080-","T186081-","T186082-","A186083-","C186084-","A186085-","G186086-","C186087-","A186088-","A186089-","C186090-","C186091-","T186092-","C186093-","C186094-","T186095-","T186096-","A186097-","C186098-","A186099-","C186100-","A186101-","T186102-","T186103-","C186104-","G186105-","A186106-","A186107-","T186108-","T186109-","C186110-","A186111-","T186112-","T186113-","C186114-","A186115-","T186116-","G186117-","A186118-","C186119-","A186120-","A186121-","T186122-","T186123-","C186124-","T186125-","A186126-","A186127-","C186128-","G186129-","A186130-","A186131-","T186132-","A186133-","T186134-","G186135-","T186136-","G186137-","G186138-","A186139-","T186140-","A186141-","A186142-","A186143-","G186144-","A186145-","A186146-","A186147-","T186148-","T186149-","A186150-","G186151-","T186152-","A186153-","A186154-","C186155-","A186156-","A186157-","A186158-","T186159-","T186160-","A186161-","A186162-","A186163-","T186164-","G186165-","A186166-","T186167-","C186168-","T186169-","G186170-","T186171-","A186172-","C186173-","A186174-","A186175-","T186176-","G186177-","A186178-","A186179-","T186180-","A186181-","C186182-","A186183-","A186184-","G186185-","A186186-","A186187-","G186188-","A186189-","T186190-","T186191-","A186192-","T186193-","G186194-","G186195-","A186196-","A186197-","T186198-","A186199-","T186200-","A186201-","G186202-","C186203-","G186204-","A186205-","C186206-","G186207-","G186208-","A186209-","T186210-","C186211-","A186212-","T186213-","T186214-","G186215-","C186216-","C186217-","G186218-","G186219-","C186220-","G186221-","T186222-","C186223-","T186224-","A186225-","T186226-","A186227-","A186228-","A186229-","C186230-","A186231-","G186232-","A186233-","T186234-","T186235-","A186236-","G186237-","C186238-","A186239-","A186240-","A186241-","G186242-","G186243-","C186244-","A186245-","T186246-","T186247-","G186248-","A186249-","C186250-","T186251-","T186252-","C186253-","A186254-","G186255-","A186256-","G186257-","G186258-","G186259-","T186260-","A186261-","G186262-","A186263-","G186264-","A186265-","A186266-","A186267-","T186268-","A186269-","G186270-","C186271-","A186272-","A186273-","G186274-","T186275-","G186276-","T186277-","T186278-","A186279-","A186280-","T186281-","A186282-","T186283-","A186284-","G186285-","A186286-","T186287-","G186288-","G186289-","T186290-","A186291-","A186292-","T186293-","C186294-","T186295-","G186296-","T186297-","T186298-","A186299-","G186300-","A186301-","T186302-","A186303-","T186304-","C186305-","G186306-","C186307-","A186308-","T186309-","A186310-","T186311-","C186312-","A186313-","A186314-","G186315-","C186316-","A186317-","G186318-","A186319-","T186320-","A186321-","A186322-","G186323-","G186324-","A186325-","A186326-","A186327-","A186328-","G186329-","A186330-","T186331-","G186332-","G186333-","C186334-","C186335-","G186336-","A186337-","C186338-","A186339-","T186340-","A186341-","C186342-","A186343-","G186344-","A186345-","C186346-","A186347-","A186348-","G186349-","A186350-","A186351-","T186352-","A186353-","A186354-","A186355-","T186356-","G186357-","A186358-","T186359-","A186360-","T186361-","T186362-","A186363-","T186364-","T186365-","A186366-","G186367-","A186368-","G186369-","A186370-","T186371-","T186372-","T186373-","G186374-","T186375-","T186376-","T186377-","A186378-","T186379-","A186380-","C186381-","A186382-","C186383-","A186384-","C186385-","T186386-","C186387-","T186388-","A186389-","T186390-","C186391-","A186392-","G186393-","A186394-","C186395-","A186396-","A186397-","A186398-","G186399-","A186400-","T186401-","A186402-","T186403-","A186404-","A186405-","A186406-","A186407-","G186408-","A186409-","C186410-","A186411-","T186412-","T186413-","A186414-","T186415-","A186416-","G186417-","A186418-","A186419-","T186420-","C186421-","C186422-","G186423-","A186424-","A186425-","G186426-","A186427-","A186428-","G186429-","G186430-","T186431-","A186432-","A186433-","G186434-","A186435-","G186436-","A186437-","T186438-","G186439-","T186440-","T186441-","G186442-","T186443-","A186444-","T186445-","A186446-","A186447-","T186448-","A186449-","G186450-","A186451-","T186452-","G186453-","T186454-","T186455-","A186456-","A186457-","G186458-","A186459-","A186460-","C186461-","A186462-","A186463-","T186464-","C186465-","T186466-","T186467-","G186468-","T186469-","T186470-","A186471-","A186472-","A186473-","A186474-","A186475-","G186476-","T186477-","A186478-","C186479-","T186480-","A186481-","T186482-","T186483-","C186484-","T186485-","A186486-","T186487-","T186488-","G186489-","A186490-","T186491-","A186492-","A186493-","T186494-","T186495-","A186496-","T186497-","C186498-","T186499-","A186500-","T186501-","G186502-","T186503-","G186504-","A186505-","T186506-","A186507-","C186508-","T186509-","T186510-","T186511-","A186512-","G186513-","A186514-","T186515-","G186516-","A186517-","T186518-","T186519-","A186520-","T186521-","A186522-","T186523-","A186524-","T186525-","A186526-","C186527-","A186528-","C186529-","C186530-","T186531-","C186532-","T186533-","G186534-","T186535-","A186536-","G186537-","A186538-","A186539-","T186540-","A186541-","T186542-","A186543-","A186544-","C186545-","A186546-","A186547-","A186548-","T186549-","C186550-","C186551-","T186552-","A186553-","T186554-","G186555-","T186556-","G186557-","T186558-","T186559-","A186560-","G186561-","T186562-","A186563-","A186564-","A186565-","C186566-","G186567-","A186568-","T186569-","A186570-","C186571-","T186572-","T186573-","A186574-","T186575-","A186576-","T186577-","G186578-","A186579-","G186580-","C186581-","T186582-","A186583-","T186584-","G186585-","A186586-","C186587-","T186588-","A186589-","T186590-","C186591-","T186592-","T186593-","G186594-","A186595-","A186596-","T186597-","C186598-","A186599-","T186600-","C186601-","A186602-","G186603-","G186604-","T186605-","G186606-","T186607-","A186608-","G186609-","T186610-","T186611-","G186612-","T186613-","T186614-","C186615-","T186616-","A186617-","T186618-","C186619-","A186620-","T186621-","G186622-","T186623-","T186624-","A186625-","T186626-","G186627-","A186628-","A186629-","A186630-","T186631-","G186632-","A186633-","C186634-","T186635-","A186636-","T186637-","A186638-","A186639-","T186640-","C186641-","T186642-","C186643-","C186644-","T186645-","T186646-","G186647-","G186648-","A186649-","T186650-","A186651-","C186652-","A186653-","A186654-","A186655-","A186656-","G186657-","A186658-","C186659-","G186660-","C186661-","C186662-","A186663-","A186664-","A186665-","G186666-","A186667-","T186668-","G186669-","C186670-","T186671-","A186672-","T186673-","A186674-","G186675-","A186676-","A186677-","G186678-","A186679-","T186680-","G186681-","T186682-","G186683-","A186684-","T186685-","A186686-","G186687-","T186688-","A186689-","G186690-","C186691-","A186692-","A186693-","G186694-","T186695-","G186696-","C186697-","G186698-","G186699-","T186700-","A186701-","G186702-","C186703-","C186704-","G186705-","A186706-","A186707-","G186708-","C186709-","A186710-","T186711-","T186712-","G186713-","A186714-","A186715-","T186716-","G186717-","A186718-","C186719-","A186720-","T186721-","G186722-","T186723-","T186724-","T186725-","A186726-","A186727-","G186728-","G186729-","A186730-","A186731-","T186732-","T186733-","T186734-","G186735-","A186736-","T186737-","A186738-","A186739-","A186740-","A186741-","A186742-","C186743-","G186744-","T186745-","A186746-","A186747-","G186748-","T186749-","G186750-","C186751-","T186752-","A186753-","T186754-","T186755-","A186756-","T186757-","A186758-","A186759-","T186760-","A186761-","A186762-","A186763-","A186764-","G186765-","A186766-","A186767-","G186768-","A186769-","A186770-","G186771-","A186772-","T186773-","A186774-","A186775-","T186776-","T186777-","A186778-","T186779-","C186780-","T186781-","A186782-","A186783-","A186784-","C186785-","A186786-","G186787-","T186788-","T186789-","C186790-","G186791-","C186792-","C186793-","C186794-","G186795-","A186796-","T186797-","A186798-","T186799-","C186800-","T186801-","A186802-","C186803-","C186804-","A186805-","T186806-","A186807-","T186808-","A186809-","A186810-","T186811-","A186812-","T186813-","A186814-","T186815-","A186816-","T186817-","C186818-","A186819-","T186820-","A186821-","G186822-","G186823-","T186824-","G186825-","G186826-","C186827-","A186828-","C186829-","T186830-","A186831-","T186832-","T186833-","C186834-","T186835-","G186836-","C186837-","T186838-","A186839-","C186840-","T186841-","G186842-","T186843-","T186844-","A186845-","G186846-","T186847-","C186848-","A186849-","T186850-","T186851-","A186852-","T186853-","T186854-","T186855-","T186856-","A186857-","A186858-","T186859-","A186860-","T186861-","T186862-","G186863-","G186864-","C186865-","A186866-","A186867-","T186868-","T186869-","T186870-","A186871-","T186872-","A186873-","T186874-","A186875-","G186876-","C186877-","G186878-","C186879-","G186880-","C186881-","A186882-","A186883-","T186884-","A186885-","A186886-","A186887-","T186888-","A186889-","C186890-","A186891-","G186892-","A186893-","A186894-","C186895-","C186896-","A186897-","G186898-","G186899-","A186900-","A186901-","A186902-","T186903-","A186904-","T186905-","G186906-","A186907-","A186908-","A186909-","T186910-","A186911-","A186912-","T186913-","G186914-","A186915-","A186916-","A186917-","T186918-","A186919-","T186920-","G186921-","A186922-","C186923-","A186924-","A186925-","T186926-","A186927-","T186928-","G186929-","A186930-","G186931-","C186932-","A186933-","T186934-","T186935-","A186936-","A186937-","A186938-","T186939-","C186940-","T186941-","G186942-","A186943-","G186944-","C186945-","A186946-","T186947-","C186948-","A186949-","T186950-","G186951-","A186952-","T186953-","A186954-","G186955-","T186956-","C186957-","T186958-","T186959-","G186960-","A186961-","A186962-","A186963-","C186964-","A186965-","G186966-","T186967-","G186968-","T186969-","C186970-","T186971-","A186972-","T186973-","G186974-","G186975-","A186976-","A186977-","A186978-","T186979-","T186980-","A186981-","T186982-","T186983-","G186984-","A186985-","T186986-","A186987-","A186988-","T186989-","C186990-","G186991-","G186992-","T186993-","A186994-","C186995-","T186996-","A186997-","A186998-","T186999-","A187000-","A187001-","A187002-","A187003-","T187004-","A187005-","G187006-","T187007-","T187008-","T187009-","A187010-","A187011-","C187012-","T187013-","C187014-","T187015-","T187016-","T187017-","T187018-","A187019-","G187020-","A187021-","A187022-","C187023-","C187024-","A187025-","G187026-","T187027-","T187028-","T187029-","G187030-","G187031-","T187032-","A187033-","C187034-","T187035-","G187036-","T187037-","A187038-","A187039-","T187040-","T187041-","T187042-","C187043-","A187044-","G187045-","T187046-","T187047-","C187048-","A187049-","T187050-","T187051-","A187052-","C187053-","T187054-","C187055-","G187056-","T187057-","T187058-","G187059-","A187060-","G187061-","A187062-","A187063-","T187064-","A187065-","T187066-","T187067-","G187068-","A187069-","T187070-","G187071-","A187072-","T187073-","T187074-","T187075-","T187076-","T187077-","T187078-","T187079-","T187080-","A187081-","A187082-","A187083-","T187084-","G187085-","A187086-","G187087-","T187088-","A187089-","T187090-","C187091-","G187092-","G187093-","T187094-","A187095-","G187096-","T187097-","T187098-","A187099-","C187100-","A187101-","T187102-","A187103-","T187104-","T187105-","A187106-","C187107-","C187108-","A187109-","T187110-","A187111-","T187112-","C187113-","A187114-","T187115-","C187116-","C187117-","A187118-","T187119-","T187120-","A187121-","T187122-","A187123-","T187124-","A187125-","A187126-","T187127-","C187128-","G187129-","A187130-","T187131-","G187132-","A187133-","T187134-","G187135-","C187136-","A187137-","T187138-","G187139-","T187140-","A187141-","T187142-","T187143-","A187144-","G187145-","A187146-","A187147-","T187148-","A187149-","C187150-","T187151-","T187152-","T187153-","C187154-","C187155-","G187156-","A187157-","A187158-","T187159-","A187160-","A187161-","G187162-","T187163-","C187164-","T187165-","T187166-","C187167-","T187168-","A187169-","A187170-","A187171-","T187172-","A187173-","T187174-","T187175-","G187176-","T187177-","A187178-","T187179-","T187180-","A187181-","A187182-","T187183-","T187184-","A187185-","T187186-","G187187-","A187188-","A187189-","A187190-","A187191-","A187192-","C187193-","T187194-","A187195-","T187196-","G187197-","C187198-","T187199-","A187200-","T187201-","G187202-","T187203-","G187204-","A187205-","G187206-","T187207-","A187208-","T187209-","G187210-","A187211-","T187212-","T187213-","C187214-","A187215-","A187216-","A187217-","G187218-","A187219-","T187220-","G187221-","T187222-","T187223-","T187224-","A187225-","A187226-","T187227-","G187228-","A187229-","T187230-","A187231-","C187232-","G187233-","A187234-","T187235-","A187236-","C187237-","T187238-","A187239-","G187240-","A187241-","T187242-","T187243-","T187244-","T187245-","A187246-","T187247-","C187248-","T187249-","C187250-","T187251-","A187252-","G187253-","C187254-","G187255-","A187256-","G187257-","A187258-","T187259-","T187260-","G187261-","T187262-","T187263-","T187264-","A187265-","G187266-","A187267-","A187268-","T187269-","C187270-","A187271-","T187272-","T187273-","T187274-","A187275-","T187276-","C187277-","A187278-","T187279-","A187280-","A187281-","C187282-","T187283-","A187284-","T187285-","G187286-","T187287-","T187288-","T187289-","A187290-","A187291-","T187292-","A187293-","A187294-","A187295-","T187296-","T187297-","C187298-","A187299-","T187300-","C187301-","A187302-","A187303-","C187304-","G187305-","A187306-","A187307-","T187308-","A187309-","T187310-","C187311-","G187312-","A187313-","T187314-","A187315-","A187316-","A187317-","G187318-","A187319-","C187320-","C187321-","T187322-","C187323-","T187324-","T187325-","G187326-","T187327-","A187328-","A187329-","T187330-","T187331-","C187332-","G187333-","A187334-","G187335-","T187336-","A187337-","T187338-","A187339-","G187340-","G187341-","A187342-","A187343-","G187344-","T187345-","A187346-","G187347-","T187348-","A187349-","T187350-","T187351-","A187352-","C187353-","C187354-","A187355-","T187356-","A187357-","T187358-","C187359-","A187360-","A187361-","C187362-","T187363-","T187364-","C187365-","C187366-","G187367-","A187368-","G187369-","T187370-","T187371-","A187372-","A187373-","C187374-","A187375-","A187376-","T187377-","T187378-","A187379-","C187380-","T187381-","C187382-","T187383-","A187384-","A187385-","A187386-","A187387-","C187388-","A187389-","T187390-","G187391-","A187392-","G187393-","G187394-","A187395-","T187396-","T187397-","G187398-","T187399-","A187400-","C187401-","T187402-","C187403-","C187404-","T187405-","G187406-","T187407-","C187408-","T187409-","T187410-","T187411-","A187412-","T187413-","T187414-","G187415-","G187416-","A187417-","G187418-","A187419-","T187420-","C187421-","A187422-","C187423-","T187424-","A187425-","T187426-","T187427-","T187428-","A187429-","G187430-","T187431-","C187432-","G187433-","T187434-","T187435-","G187436-","A187437-","T187438-","A187439-","A187440-","A187441-","C187442-","T187443-","A187444-","G187445-","T187446-","A187447-","A187448-","C187449-","C187450-","T187451-","C187452-","A187453-","G187454-","G187455-","T187456-","T187457-","T187458-","C187459-","T187460-","T187461-","T187462-","A187463-","C187464-","A187465-","A187466-","A187467-","C187468-","G187469-","A187470-","T187471-","A187472-","A187473-","A187474-","G187475-","T187476-","A187477-","C187478-","A187479-","A187480-","C187481-","A187482-","T187483-","C187484-","A187485-","A187486-","G187487-","A187488-","C187489-","C187490-","T187491-","C187492-","A187493-","C187494-","A187495-","A187496-","C187497-","A187498-","C187499-","A187500-","G187501-","T187502-","G187503-","C187504-","A187505-","A187506-","G187507-","A187508-","T187509-","T187510-","A187511-","A187512-","T187513-","C187514-","T187515-","A187516-","G187517-","A187518-","A187519-","A187520-","T187521-","C187522-","A187523-","A187524-","A187525-","T187526-","G187527-","T187528-","A187529-","A187530-","T187531-","T187532-","C187533-","T187534-","G187535-","G187536-","A187537-","G187538-","G187539-","A187540-","G187541-","A187542-","A187543-","T187544-","C187545-","T187546-","A187547-","G187548-","A187549-","C187550-","A187551-","A187552-","C187553-","T187554-","A187555-","A187556-","C187557-","A187558-","C187559-","C187560-","C187561-","A187562-","C187563-","G187564-","G187565-","C187566-","G187567-","A187568-","A187569-","G187570-","T187571-","A187572-","T187573-","A187574-","C187575-","T187576-","T187577-","T187578-","A187579-","T187580-","G187581-","C187582-","C187583-","T187584-","C187585-","A187586-","T187587-","T187588-","C187589-","A187590-","G187591-","A187592-","A187593-","A187594-","C187595-","G187596-","G187597-","T187598-","A187599-","A187600-","C187601-","T187602-","G187603-","T187604-","A187605-","G187606-","T187607-","A187608-","G187609-","G187610-","A187611-","G187612-","A187613-","C187614-","T187615-","G187616-","T187617-","C187618-","T187619-","C187620-","T187621-","C187622-","T187623-","A187624-","A187625-","T187626-","C187627-","T187628-","C187629-","G187630-","A187631-","T187632-","G187633-","T187634-","A187635-","T187636-","A187637-","T187638-","A187639-","T187640-","A187641-","A187642-","T187643-","A187644-","T187645-","A187646-","T187647-","A187648-","C187649-","C187650-","A187651-","A187652-","T187653-","A187654-","C187655-","G187656-","G187657-","A187658-","C187659-","G187660-","C187661-","G187662-","A187663-","T187664-","A187665-","T187666-","A187667-","T187668-","T187669-","C187670-","C187671-","G187672-","A187673-","C187674-","A187675-","T187676-","G187677-","A187678-","A187679-","T187680-","G187681-","G187682-","C187683-","G187684-","T187685-","C187686-","G187687-","C187688-","T187689-","T187690-","A187691-","T187692-","C187693-","A187694-","T187695-","A187696-","T187697-","G187698-","T187699-","T187700-","A187701-","T187702-","A187703-","T187704-","C187705-","C187706-","T187707-","A187708-","A187709-","A187710-","T187711-","G187712-","T187713-","T187714-","G187715-","A187716-","T187717-","C187718-","A187719-","T187720-","A187721-","T187722-","T187723-","C187724-","C187725-","A187726-","C187727-","A187728-","A187729-","A187730-","T187731-","G187732-","A187733-","T187734-","T187735-","G187736-","T187737-","G187738-","A187739-","A187740-","C187741-","G187742-","A187743-","G187744-","A187745-","T187746-","T187747-","A187748-","A187749-","A187750-","T187751-","C187752-","A187753-","T187754-","C187755-","T187756-","A187757-","A187758-","C187759-","A187760-","A187761-","A187762-","T187763-","A187764-","A187765-","T187766-","T187767-","A187768-","G187769-","T187770-","T187771-","T187772-","T187773-","T187774-","T187775-","A187776-","T187777-","G187778-","A187779-","C187780-","A187781-","T187782-","T187783-","A187784-","A187785-","C187786-","A187787-","T187788-","A187789-","T187790-","A187791-","A187792-","T187793-","A187794-","A187795-","A187796-","T187797-","A187798-","A187799-","A187800-","T187801-","T187802-","A187803-","A187804-","T187805-","C187806-","A187807-","T187808-","T187809-","A187810-","T187811-","T187812-","G187813-","A187814-","C187815-","T187816-","T187817-","A187818-","A187819-","C187820-","G187821-","A187822-","T187823-","G187824-","A187825-","C187826-","G187827-","A187828-","A187829-","A187830-","G187831-","T187832-","T187833-","A187834-","T187835-","C187836-","A187837-","T187838-","T187839-","A187840-","T187841-","C187842-","T187843-","T187844-","A187845-","G187846-","G187847-","A187848-","T187849-","T187850-","C187851-","T187852-","T187853-","G187854-","A187855-","T187856-","T187857-","A187858-","T187859-","T187860-","A187861-","A187862-","T187863-","A187864-","C187865-","A187866-","A187867-","A187868-","T187869-","T187870-","C187871-","G187872-","T187873-","T187874-","G187875-","T187876-","G187877-","T187878-","C187879-","T187880-","A187881-","T187882-","G187883-","A187884-","A187885-","A187886-","T187887-","G187888-","T187889-","G187890-","A187891-","A187892-","C187893-","A187894-","A187895-","G187896-","G187897-","T187898-","G187899-","T187900-","C187901-","T187902-","C187903-","A187904-","T187905-","A187906-","T187907-","T187908-","A187909-","T187910-","A187911-","A187912-","T187913-","G187914-","C187915-","A187916-","C187917-","A187918-","A187919-","G187920-","A187921-","A187922-","T187923-","T187924-","A187925-","A187926-","A187927-","G187928-","T187929-","G187930-","T187931-","T187932-","G187933-","T187934-","A187935-","A187936-","A187937-","C187938-","T187939-","A187940-","T187941-","C187942-","T187943-","A187944-","G187945-","C187946-","C187947-","A187948-","G187949-","G187950-","A187951-","A187952-","C187953-","A187954-","T187955-","A187956-","T187957-","T187958-","C187959-","A187960-","G187961-","A187962-","T187963-","T187964-","A187965-","T187966-","C187967-","G187968-","A187969-","T187970-","G187971-","T187972-","G187973-","A187974-","T187975-","A187976-","A187977-","A187978-","T187979-","A187980-","C187981-","A187982-","G187983-","C187984-","G187985-","A187986-","T187987-","A187988-","C187989-","C187990-","A187991-","T187992-","C187993-","T187994-","G187995-","T187996-","G187997-","G187998-","A187999-","C188000-","A188001-","T188002-","T188003-","G188004-","T188005-","C188006-","C188007-","A188008-","A188009-","G188010-","T188011-","G188012-","A188013-","C188014-","A188015-","C188016-","A188017-","T188018-","T188019-","C188020-","A188021-","C188022-","G188023-","T188024-","C188025-","A188026-","A188027-","T188028-","A188029-","T188030-","A188031-","T188032-","A188033-","A188034-","T188035-","C188036-","G188037-","T188038-","T188039-","C188040-","T188041-","C188042-","C188043-","T188044-","C188045-","G188046-","G188047-","T188048-","G188049-","T188050-","C188051-","A188052-","T188053-","A188054-","G188055-","T188056-","T188057-","G188058-","T188059-","A188060-","G188061-","A188062-","G188063-","G188064-","T188065-","C188066-","A188067-","C188068-","A188069-","C188070-","C188071-","T188072-","T188073-","G188074-","T188075-","A188076-","C188077-","A188078-","C188079-","C188080-","T188081-","A188082-","C188083-","C188084-","A188085-","C188086-","A188087-","A188088-","A188089-","T188090-","A188091-","G188092-","A188093-","A188094-","T188095-","A188096-","T188097-","G188098-","T188099-","C188100-","A188101-","T188102-","T188103-","G188104-","T188105-","G188106-","A188107-","C188108-","T188109-","C188110-","G188111-","A188112-","A188113-","T188114-","A188115-","G188116-","T188117-","T188118-","A188119-","T188120-","C188121-","G188122-","T188123-","C188124-","T188125-","C188126-","C188127-","T188128-","T188129-","A188130-","A188131-","A188132-","G188133-","C188134-","T188135-","T188136-","C188137-","T188138-","G188139-","A188140-","T188141-","G188142-","G188143-","T188144-","A188145-","A188146-","C188147-","T188148-","G188149-","T188150-","G188151-","T188152-","T188153-","A188154-","C188155-","A188156-","T188157-","G188158-","T188159-","G188160-","C188161-","T188162-","C188163-","C188164-","T188165-","A188166-","A188167-","A188168-","A188169-","C188170-","A188171-","A188172-","A188173-","A188174-","T188175-","A188176-","T188177-","G188178-","G188179-","T188180-","C188181-","G188182-","T188183-","G188184-","T188185-","G188186-","T188187-","A188188-","C188189-","G188190-","G188191-","A188192-","A188193-","A188194-","G188195-","A188196-","A188197-","A188198-","G188199-","G188200-","A188201-","G188202-","A188203-","A188204-","A188205-","A188206-","T188207-","G188208-","A188209-","T188210-","A188211-","T188212-","G188213-","G188214-","A188215-","A188216-","T188217-","A188218-","C188219-","C188220-","A188221-","T188222-","T188223-","T188224-","G188225-","T188226-","A188227-","A188228-","G188229-","A188230-","A188231-","A188232-","T188233-","G188234-","T188235-","C188236-","G188237-","G188238-","A188239-","A188240-","G188241-","G188242-","G188243-","T188244-","A188245-","C188246-","T188247-","T188248-","A188249-","T188250-","T188251-","C188252-","A188253-","G188254-","A188255-","T188256-","A188257-","T188258-","T188259-","G188260-","T188261-","A188262-","T188263-","C188264-","T188265-","G188266-","A188267-","C188268-","T188269-","C188270-","T188271-","G188272-","A188273-","T188274-","C188275-","A188276-","A188277-","T188278-","G188279-","T188280-","A188281-","A188282-","A188283-","C188284-","C188285-","T188286-","A188287-","T188288-","G188289-","A188290-","C188291-","A188292-","A188293-","G188294-","A188295-","T188296-","A188297-","A188298-","G188299-","A188300-","C188301-","T188302-","T188303-","A188304-","C188305-","T188306-","C188307-","G188308-","C188309-","A188310-","T188311-","C188312-","T188313-","A188314-","C188315-","T188316-","G188317-","G188318-","A188319-","T188320-","A188321-","G188322-","A188323-","C188324-","A188325-","T188326-","A188327-","A188328-","A188329-","T188330-","A188331-","T188332-","C188333-","C188334-","T188335-","C188336-","C188337-","T188338-","C188339-","G188340-","T188341-","A188342-","A188343-","T188344-","A188345-","A188346-","T188347-","G188348-","A188349-","A188350-","A188351-","T188352-","A188353-","T188354-","A188355-","A188356-","T188357-","A188358-","T188359-","A188360-","C188361-","A188362-","C188363-","T188364-","A188365-","A188366-","T188367-","T188368-","A188369-","T188370-","T188371-","A188372-","A188373-","T188374-","A188375-","T188376-","C188377-","A188378-","A188379-","T188380-","C188381-","G188382-","A188383-","G188384-","T188385-","A188386-","T188387-","T188388-","A188389-","A188390-","C188391-","A188392-","T188393-","A188394-","T188395-","A188396-","A188397-","G188398-","T188399-","T188400-","A188401-","T188402-","T188403-","T188404-","T188405-","T188406-","A188407-","A188408-","A188409-","C188410-","C188411-","C188412-","C188413-","T188414-","T188415-","T188416-","T188417-","G188418-","G188419-","G188420-","T188421-","T188422-","C188423-","C188424-","G188425-","T188426-","C188427-","C188428-","T188429-","A188430-","A188431-","A188432-","C188433-","G188434-","G188435-","C188436-","G188437-","T188438-","T188439-","T188440-","C188441-","G188442-","G188443-","T188444-","C188445-","T188446-","G188447-","T188448-","G188449-","T188450-","C188451-","G188452-","C188453-","C188454-","A188455-","C188456-","C188457-","A188458-","T188459-","G188460-","G188461-","T188462-","C188463-","A188464-","C188465-","A188466-","C188467-","C188468-","G188469-","A188470-","G188471-","C188472-","C188473-","T188474-","C188475-","T188476-","G188477-","C188478-","G188479-","T188480-","G188481-","C188482-","T188483-","C188484-","C188485-","T188486-","C188487-","C188488-","A188489-","T188490-","C188491-","G188492-","A188493-","G188494-","G188495-","A188496-","C188497-","G188498-","A188499-","C188500-","T188501-","T188502-","C188503-","A188504-","A188505-","C188506-","T188507-","A188508-","T188509-","G188510-","A188511-","C188512-","A188513-","G188514-","C188515-","T188516-","C188517-","G188518-","G188519-","T188520-","G188521-","G188522-","C188523-","G188524-","T188525-","C188526-","T188527-","G188528-","C188529-","C188530-","A188531-","G188532-","C188533-","G188534-","T188535-","G188536-","T188537-","A188538-","C188539-","A188540-","T188541-","A188542-","C188543-","G188544-","A188545-","A188546-","T188547-","G188548-","G188549-","C188550-","A188551-","T188552-","T188553-","T188554-","C188555-","T188556-","A188557-","A188558-","G188559-","A188560-","A188561-","A188562-","A188563-","G188564-","T188565-","C188566-","T188567-","A188568-","C188569-","G188570-","G188571-","T188572-","A188573-","T188574-","C188575-","C188576-","T188577-","T188578-","T188579-","C188580-","T188581-","A188582-","C188583-","A188584-","A188585-","T188586-","T188587-","T188588-","C188589-","C188590-","T188591-","T188592-","T188593-","A188594-","A188595-","C188596-","A188597-","A188598-","C188599-","G188600-","G188601-","C188602-","A188603-","A188604-","C188605-","A188606-","G188607-","C188608-","T188609-","G188610-","C188611-","A188612-","G188613-","T188614-","A188615-","T188616-","T188617-","T188618-","T188619-","T188620-","A188621-","T188622-","A188623-","C188624-","T188625-","T188626-","T188627-","G188628-","A188629-","A188630-","T188631-","G188632-","C188633-","A188634-","T188635-","C188636-","G188637-","G188638-","A188639-","C188640-","A188641-","T188642-","T188643-","T188644-","A188645-","T188646-","A188647-","C188648-","A188649-","A188650-","G188651-","G188652-","G188653-","A188654-","G188655-","T188656-","C188657-","C188658-","T188659-","G188660-","T188661-","T188662-","C188663-","T188664-","A188665-","A188666-","T188667-","A188668-","T188669-","T188670-","G188671-","G188672-","C188673-","A188674-","T188675-","C188676-","A188677-","A188678-","T188679-","G188680-","T188681-","T188682-","C188683-","G188684-","G188685-","A188686-","T188687-","C188688-","T188689-","A188690-","T188691-","A188692-","G188693-","G188694-","C188695-","T188696-","T188697-","G188698-","A188699-","T188700-","T188701-","T188702-","T188703-","C188704-","G188705-","C188706-","A188707-","T188708-","T188709-","G188710-","A188711-","C188712-","T188713-","T188714-","T188715-","A188716-","C188717-","A188718-","C188719-","A188720-","G188721-","A188722-","C188723-","A188724-","T188725-","G188726-","A188727-","A188728-","C188729-","A188730-","T188731-","C188732-","C188733-","C188734-","C188735-","T188736-","G188737-","A188738-","A188739-","T188740-","C188741-","T188742-","G188743-","T188744-","A188745-","C188746-","A188747-","T188748-","A188749-","C188750-","T188751-","T188752-","T188753-","G188754-","T188755-","G188756-","G188757-","A188758-","T188759-","T188760-","T188761-","A188762-","C188763-","A188764-","C188765-","T188766-","G188767-","T188768-","T188769-","A188770-","G188771-","A188772-","A188773-","T188774-","C188775-","T188776-","C188777-","T188778-","A188779-","A188780-","C188781-","G188782-","C188783-","T188784-","G188785-","G188786-","C188787-","C188788-","T188789-","C188790-","T188791-","G188792-","T188793-","T188794-","G188795-","T188796-","T188797-","A188798-","C188799-","T188800-","T188801-","T188802-","C188803-","T188804-","A188805-","T188806-","G188807-","A188808-","T188809-","G188810-","C188811-","A188812-","C188813-","G188814-","T188815-","A188816-","T188817-","C188818-","G188819-","T188820-","T188821-","A188822-","T188823-","G188824-","C188825-","A188826-","A188827-","G188828-","C188829-","T188830-","T188831-","T188832-","C188833-","A188834-","T188835-","G188836-","T188837-","T188838-","G188839-","A188840-","C188841-","T188842-","A188843-","C188844-","T188845-","G188846-","C188847-","A188848-","G188849-","T188850-","G188851-","T188852-","T188853-","T188854-","C188855-","T188856-","T188857-","G188858-","C188859-","T188860-","C188861-","T188862-","G188863-","A188864-","C188865-","T188866-","A188867-","C188868-","A188869-","T188870-","A188871-","T188872-","A188873-","C188874-","T188875-","C188876-","T188877-","A188878-","C188879-","A188880-","A188881-","T188882-","C188883-","A188884-","A188885-","A188886-","G188887-","A188888-","G188889-","A188890-","G188891-","A188892-","T188893-","T188894-","T188895-","C188896-","A188897-","G188898-","T188899-","A188900-","A188901-","A188902-","C188903-","T188904-","T188905-","G188906-","T188907-","A188908-","A188909-","C188910-","A188911-","G188912-","G188913-","A188914-","T188915-","T188916-","G188917-","T188918-","T188919-","T188920-","G188921-","C188922-","T188923-","G188924-","C188925-","T188926-","T188927-","T188928-","C188929-","T188930-","G188931-","G188932-","A188933-","T188934-","-196616A"],"OPG023":["D392N"],"OPG057":["E353K"]},"labels":{"aa":"OPG023: D392N; OPG057: E353K"}}},{"name":"OP612688","node_attrs":{"div":28,"accession":"OP612688","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"strain":{"value":"MPXV/104/19"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP612688/2019-11-02"},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"date":{"value":"2019-11-02"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","G1126A","G2039A","G2152A","C6948T","C47224T","T76087-","C77726T","C143845T","G152431A","C166786T","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","G184037T","C184535T","C195058T","C195171T","C196084T"],"OPG002":["S238L"],"OPG002_dup":["S238L"],"OPG066":["E69K"],"OPG099":["S21F"],"OPG192":["S19L"]},"labels":{"aa":"OPG002: S238L; OPG002_dup: S238L; OPG066: E69K; OPG099: S21F; OPG192: S19L"}}},{"name":"OP612674","node_attrs":{"div":23,"accession":"OP612674","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"strain":{"value":"MPXV/003/19"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP612674/2019-01-12"},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"date":{"value":"2019-01-12"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["C11555T","G28645A","G75967A","T76087-","G94840A","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","C188503T","A196612-","A196613-","A196614-","A196615-"],"OPG023":["R449Q"],"OPG115":["E61K"]},"labels":{"aa":"OPG023: R449Q; OPG115: E61K"}}},{"name":"NODE_0000028","node_attrs":{"div":19,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","G151929A","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","-196616A","-196617A"],"OPG178":["E141K"]},"labels":{"aa":"OPG178: E141K"}},"children":[{"name":"OL504743","node_attrs":{"div":27,"accession":"OL504743","author":{"author":"Atkinson,B.,Pottage,T.,Ngabo,D.,Crook,A.,Pitman,J.,Summers,S.,Pullan,S.,Lewandowski,K.,Furneaux,J.,Davies,K.,Brooks,T.","value":"Atkinson,B.,Pottage,T.,Ngabo,D.,Crook,A.,Pitman,J.,Summers,S.,Pullan,S.,Lewandowski,K.,Furneaux,J.,Davies,K.,Brooks,T."},"strain":{"value":"2102"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"strain_display":{"value":"United Kingdom/OL504743/2019-12-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research"},"date":{"value":"2019-12-XX"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["C5477G","C13065T","C29887T","G61329A","C72206T","G103431A","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","C165369T","-173290A","-173291T","-173292A","-173293T","-173294A","-173295T","-173296A","-173297T","-173298A","-173299T","-173300A","-173301T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G188949A","A191442G"],"OPG015":["R227P"],"OPG015_dup":["E130G"],"OPG024":["G55E"],"OPG092":["E248K"],"OPG123":["S547L"],"OPG190":["S83F"]},"labels":{"aa":"OPG015: R227P; OPG015_dup: E130G; OPG024: G55E; OPG092: E248K; OPG123: S547L; OPG190: S83F"}}},{"name":"OP612683","node_attrs":{"div":21,"accession":"OP612683","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"strain":{"value":"MPXV/042/19"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP612683/2019-04-18"},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"date":{"value":"2019-04-18"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["-608T","T76087-","G81523A","C141757T"],"OPG105":["S133N"]},"labels":{"aa":"OPG105: S133N"}}},{"name":"NODE_0000029","node_attrs":{"div":20,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["C39767T"]}},"children":[{"name":"MT903342","node_attrs":{"div":22,"accession":"MT903342","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"strain":{"value":"MPXV-Singapore"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Singapore/MT903342/2019-05-XX"},"country":{"value":"Singapore"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2019-05-XX"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["-608T","C43927T","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","C170573T","-173290A","-173291T","-173292A","-173293T","-173294A","-173295T","-173296A","-173297T","-173298A","-173299T","-173300A","-173301T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A196617-"],"OPG064":["E658K"],"OPG198":["S179L"]},"labels":{"aa":"OPG064: E658K; OPG198: S179L"}}},{"name":"OP612685","node_attrs":{"div":20,"accession":"OP612685","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"strain":{"value":"MPXV/052/19"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP612685/2019-05-29"},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"date":{"value":"2019-05-29"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-"]}}}]}]},{"name":"NODE_0000030","node_attrs":{"div":20,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["G25661A","C39119T","-173314A","-173315T","-173316A","-173317T"]}},"children":[{"name":"OP612679","node_attrs":{"div":28,"accession":"OP612679","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"strain":{"value":"MPXV/018/19"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP612679/2019-03-14"},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"date":{"value":"2019-03-14"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["C8500T","G79538A","G81354A","G84416A","C88736T","G100642A","C138791T","C161616T","-196616A","-196617A"],"OPG102":["D152N"],"OPG105":["E77K"],"OPG109":["E238K"],"OPG119":["R86K"],"OPG156":["D207N"]},"labels":{"aa":"OPG102: D152N; OPG105: E77K; OPG109: E238K; OPG119: R86K; OPG156: D207N"}}},{"name":"NODE_0000031","node_attrs":{"div":21,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["T607-","G162243A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","A196615-"]}},"children":[{"name":"MT903344","node_attrs":{"div":21,"accession":"MT903344","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"strain":{"value":"MPXV-UK_P2"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/MT903344/2018-09-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2018-09-XX"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["-607T","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"]}}},{"name":"MT903345","node_attrs":{"div":21,"accession":"MT903345","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"strain":{"value":"MPXV-UK_P3"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/MT903345/2018-09-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2018-09-XX"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"NODE_0000032","node_attrs":{"div":24,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["G1262A","C3818T","G124130A","C128698T","T133102-","T133177-","C133178-","T133179-","T133180-","T133181-","C133182-","T133183-","C133184-","A133185-","A133186-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179177T","-179178A","G193392A","C195948T"],"OPG001":["S105L"],"OPG001_dup":["S105L"],"OPG003":["D264N"],"OPG003_dup":["D264N"],"OPG145":["E62K"],"OPG150":["S307L"]},"labels":{"aa":"OPG001: S105L; OPG001_dup: S105L; OPG003: D264N; OPG003_dup: D264N; OPG145: E62K; OPG150: S307L"}},"children":[{"name":"OP612687","node_attrs":{"div":29,"accession":"OP612687","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"strain":{"value":"MPXV/058/19"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP612687/2019-07-11"},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"date":{"value":"2019-07-11"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","C756T","G2039A","G168365A","A173288-","T173289-","-179172C","-179173A","-179174T","-179175T","-179176A","C188605A","A188606C","G188607A","T193455A","C195171T","G196454-","A196614-"],"OPG002":["S238L"],"OPG002_dup":["S238L"],"OPG003_dup":["L285I"],"OPG195":["E46K"]},"labels":{"aa":"OPG002: S238L; OPG002_dup: S238L; OPG003_dup: L285I; OPG195: E46K"}}},{"name":"NODE_0000033","node_attrs":{"div":25,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["G81275A"]}},"children":[{"name":"OP612686","node_attrs":{"div":26,"accession":"OP612686","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"strain":{"value":"MPXV/053/19"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Nigeria/OP612686/2019-06-26"},"country":{"value":"Nigeria"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"date":{"value":"2019-06-26"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["-607T","T76087-","G88640A","-179172C","-179173A","-179174T","-179175T","-179176A","-196615A","-196616A","-196617A"],"OPG109":["R270C"]},"labels":{"aa":"OPG109: R270C"}}},{"name":"NODE_0000034","node_attrs":{"div":50,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1.1"}},"branch_attrs":{"mutations":{"nuc":["G2591A","G3522A","C7771T","G14000T","G15428A","G21723A","G30367A","G31053A","G34459A","G37202A","G38360A","C38662T","G52885A","G54117A","G54635A","G64297A","C73066T","C82373T","G82451A","G95034A","G124674A","-133102T","C162331T","-173290A","-173291T","-173292A","-173293T","-173294A","-173295T","-173296A","-173297T","-173298A","-173299T","-173300A","-173301T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","G178133A","G181980A","G186578A","C193688T","C194619T"],"OPG002":["S54F"],"OPG002_dup":["S54F"],"OPG025":["A423D"],"OPG047":["R48C"],"OPG053":["P78S"],"OPG056":["E125K"],"OPG071":["L108F"],"OPG072":["D56N"],"OPG093":["S30L"],"OPG145":["R243Q"],"OPG210":["D209N","M1741I"]},"labels":{"aa":"OPG002: S54F; OPG002_dup: S54F; OPG025: A423D; OPG047: R48C; OPG053: P78S; OPG056: E125K; OPG071: L108F; OPG072: D56N; OPG093: S30L; OPG145: R243Q; OPG210: D209N, M1741I","clade":"A.1.1"}},"children":[{"name":"ON676708","node_attrs":{"div":53,"accession":"ON676708","author":{"author":"Gigante,C.M.,Myers,R.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Blythe,D.,Li,Y.","value":"Gigante,C.M.,Myers,R.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Blythe,D.,Li,Y."},"strain":{"value":"MPXV_USA_2021_MD"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/ON676708/2021-11-XX"},"country":{"value":"USA"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2021-11-XX"},"lineage":{"value":"A.1.1"}},"branch_attrs":{"mutations":{"nuc":["C79348T","C86979T","C133714T","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"NODE_0000035","node_attrs":{"div":61,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G3111A","C39139T","G73239A","G74205A","G77383A","C84587T","C150469T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A151461C","G155795A","G170262A","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C183519T","C194099T"],"OPG057":["E353K"],"OPG093":["D88N"],"OPG094":["M142I"],"OPG098":["E162K"],"OPG176":["H221Y"],"OPG210":["P722S"]},"labels":{"aa":"OPG057: E353K; OPG093: D88N; OPG094: M142I; OPG098: E162K; OPG176: H221Y; OPG210: P722S","clade":"B.1"}},"children":[{"name":"ON585032","node_attrs":{"div":61,"accession":"ON585032","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0004/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/ON585032/2022-05-17"},"country":{"value":"Portugal"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"date":{"value":"2022-05-17"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A188351-"]}}},{"name":"OP160532","node_attrs":{"div":62,"accession":"OP160532","author":{"author":"Tutu van Furth AM,van der Kuip M,van Els AL,Fievez LC,van Rijckevorsel GG,van den Ouden A,Jonges M,Welkers MR,Welkers,M.,Jonges,M.","value":"Tutu van Furth AM,van der Kuip M,van Els AL,Fievez LC,van Rijckevorsel GG,van den Ouden A,Jonges M,Welkers MR,Welkers,M.,Jonges,M."},"strain":{"value":"hMpxV/Netherlands/NH-AUMC-0001/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Netherlands/OP160532/2022-06-XX"},"country":{"value":"Netherlands"},"institution":{"value":"Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["A148207T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G191845A","A196614-"],"OPG173":["E57D"]},"labels":{"aa":"OPG173: E57D"}}},{"name":"LC722946","node_attrs":{"div":64,"accession":"LC722946","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"strain":{"value":"MPXV/human/Japan/Tokyo/TKY220091/2022"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Japan/LC722946/2022-07-XX"},"country":{"value":"Japan"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C13653T","C116100T","G150376A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG025":["D539N"],"OPG176":["D190N"]},"labels":{"aa":"OPG025: D539N; OPG176: D190N"}}},{"name":"OP133005","node_attrs":{"div":62,"accession":"OP133005","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"strain":{"value":"hMPXV/Austria/MUW1531848/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Austria/OP133005/2022-07-05"},"country":{"value":"Austria"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["A28532-","T133098-","T133099-","T133100-","T133101-","T133102-","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188252T","A196613-","A196614-","G197058T","C197173G"],"OPG044":["M148-"]},"labels":{"aa":"OPG044: M148-"}}},{"name":"OP062233","node_attrs":{"div":61,"accession":"OP062233","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Jolly,G.,Griffiths,E.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Jolly,G.,Griffiths,E.,Charest,H.,Levade,I.,Fafard,J."},"strain":{"value":"MpxV/human/CAN/UN-NML-3913/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OP062233/2022-06-28"},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-28"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON959134","node_attrs":{"div":62,"accession":"ON959134","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_NY003"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/ON959134/2022-05-XX"},"country":{"value":"USA"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C98368T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON880517","node_attrs":{"div":62,"accession":"ON880517","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"strain":{"value":"MpxV/human/CAN/UN-NML-3476/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/ON880517/2022-05-27"},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-27"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G14611A"]}}},{"name":"ON808416","node_attrs":{"div":62,"accession":"ON808416","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"strain":{"value":"CVR_MPXV1d"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/ON808416/2022-05-15"},"country":{"value":"United Kingdom"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"date":{"value":"2022-05-15"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G20576A","T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"ON872184","node_attrs":{"div":66,"accession":"ON872184","author":{"author":"Fletcher,N.,Gonzalez,G.,Meredith,L.,Purves,K.,Carr,M.,Dean,J.,Keogan,B.,Crowley,B.,Lyons,F.,O'Reilly,S.,Gautier,V.,Mallon,P.,Gordon,S.,Connell,J.,De Gascun,C.F.","value":"Fletcher,N.,Gonzalez,G.,Meredith,L.,Purves,K.,Carr,M.,Dean,J.,Keogan,B.,Crowley,B.,Lyons,F.,O'Reilly,S.,Gautier,V.,Mallon,P.,Gordon,S.,Connell,J.,De Gascun,C.F."},"strain":{"value":"WA-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Ireland/ON872184/2022-05-30"},"country":{"value":"Ireland"},"institution":{"value":"University College Dublin, National Virus Reference Laboratory"},"date":{"value":"2022-05-30"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T48785C","G49636A","C50017T","T72809C","G178541A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG068":["G479E"],"OPG069":["T11I"],"OPG092":["K47E"]},"labels":{"aa":"OPG068: G479E; OPG069: T11I; OPG092: K47E"}}},{"name":"ON782022","node_attrs":{"div":61,"accession":"ON782022","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.,Sironen,T.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.,Sironen,T."},"strain":{"value":"MPX-42/Finland/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Finland/ON782022/2022-05-31"},"country":{"value":"Finland"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"date":{"value":"2022-05-31"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"ON751962","node_attrs":{"div":64,"accession":"ON751962","author":{"author":"Claro,I.M.,de Lima,E.L.,Romano,C.M.,Candido,D.S.,Lindoso,J.A.L.,Barra,L.A.C.,Borges,L.M.S.,Medeiros,L.A.,Tomishige,M.Y.S.,Ramundo,M.S.,Moutinho,T.,da Silva,A.J.D.,Rodrigues,C.C.M.,de Azevedo,L.C.F.,Villas-Boas,L.S.,da Silva,C.A.M.,Coletti,T.M.,O'Toole,A.,Quick,J.,Loman,N.,Rambaut,A.,Faria,N.R.,Figueiredo-Mello,C.,Sabino,E.C.","value":"Claro,I.M.,de Lima,E.L.,Romano,C.M.,Candido,D.S.,Lindoso,J.A.L.,Barra,L.A.C.,Borges,L.M.S.,Medeiros,L.A.,Tomishige,M.Y.S.,Ramundo,M.S.,Moutinho,T.,da Silva,A.J.D.,Rodrigues,C.C.M.,de Azevedo,L.C.F.,Villas-Boas,L.S.,da Silva,C.A.M.,Coletti,T.M.,O'Toole,A.,Quick,J.,Loman,N.,Rambaut,A.,Faria,N.R.,Figueiredo-Mello,C.,Sabino,E.C."},"strain":{"value":"Monkeypox/BR0001/2022"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Brazil/ON751962/2022-06-07"},"country":{"value":"Brazil"},"institution":{"value":"Imperial College London, School of Public Health"},"date":{"value":"2022-06-07"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G10118A","C15004T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G169928A","G173575-","A173576-","G173577-","A173578-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG021":["E178K"],"OPG197":["D87N"]},"labels":{"aa":"OPG021: E178K; OPG197: D87N"}}},{"name":"ON745225","node_attrs":{"div":62,"accession":"ON745225","author":{"author":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"strain":{"value":"MpxV/Spain/MD-HGUGM-66649483/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Spain/ON745225/2022-05-27"},"country":{"value":"Spain"},"institution":{"value":"HGUGM, Microbial Genomics"},"date":{"value":"2022-05-27"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G50151A","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG069":["D56N"]},"labels":{"aa":"OPG069: D56N"}}},{"name":"ON644344","node_attrs":{"div":61,"accession":"ON644344","author":{"author":"Licastro,D.,DeGasperi,M.,Negri,C.,Piscianz,E.,Koncan,R.,Dal Monego,S.,Segat,L.,D'Agaro,P.","value":"Licastro,D.,DeGasperi,M.,Negri,C.,Piscianz,E.,Koncan,R.,Dal Monego,S.,Segat,L.,D'Agaro,P."},"strain":{"value":"MPXV_FVG-ITA_01_2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Italy/ON644344/2022-05-25"},"country":{"value":"Italy"},"institution":{"value":"Genomics & Epigenomics, AREA Science Park, Italy"},"date":{"value":"2022-05-25"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C334-","A335-","C133077T","T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T173317-","G173318-","G173319-","G173320-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON622712","node_attrs":{"div":62,"accession":"ON622712","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P."},"strain":{"value":"MPX/UZ_REGA_1/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/ON622712/2022-05-19"},"country":{"value":"Belgium"},"institution":{"value":"Microbiology, Immunology & Transplantation, KU Leuven, Rega Institute, Belgium"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C46125T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG065":["R120K"]},"labels":{"aa":"OPG065: R120K"}}},{"name":"ON615424","node_attrs":{"div":63,"accession":"ON615424","author":{"author":"Oude Munnink,B.B.,Boter,M.,Wellers,B.,Molenkamp,R.,Sikkema,R.S.,Koopmans,M.","value":"Oude Munnink,B.B.,Boter,M.,Wellers,B.,Molenkamp,R.,Sikkema,R.S.,Koopmans,M."},"strain":{"value":"MPXV_2022_NL001"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Netherlands/ON615424/2022-05-XX"},"country":{"value":"Netherlands"},"institution":{"value":"Public Health Virology, Erasmus Medical Centre, The Netherlands"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155611A","G171003A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","G179362-","G179363-","-196615A"],"OPG199":["E6K"]},"labels":{"aa":"OPG199: E6K"}}},{"name":"ON595760","node_attrs":{"div":61,"accession":"ON595760","author":{"author":"Laubscher,F.,Chudzinski,V.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinski,V.,Schibler,M.,Kaiser,L.,Renzoni,A."},"strain":{"value":"MPXV-CH-38134631/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Switzerland/ON595760/2022-05-19"},"country":{"value":"Switzerland"},"institution":{"value":"Laboratory of Viorology, University Hospital of Geneva, Switzerland"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","T133101-","T133102-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"]}}},{"name":"OP341487","node_attrs":{"div":65,"accession":"OP341487","author":{"author":"Welkers,M.,Jonges,M.,de Regt,M.,Ooijevaar,R.,Wagemakers,A.","value":"Welkers,M.,Jonges,M.,de Regt,M.,Ooijevaar,R.,Wagemakers,A."},"strain":{"value":"hMpxV/Netherlands/NH-AUMC-0060/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Netherlands/OP341487/2022-08-05"},"country":{"value":"Netherlands"},"institution":{"value":"Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention"},"date":{"value":"2022-08-05"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C96773T","C109432T","C114985T","C142356T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG117":["S242L"],"OPG129":["D525N"],"OPG133":["D238N"],"OPG163":["S52F"]},"labels":{"aa":"OPG117: S242L; OPG129: D525N; OPG133: D238N; OPG163: S52F"}}},{"name":"OP324520","node_attrs":{"div":64,"accession":"OP324520","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0210/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP324520/2022-06-25"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-06-25"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C69494T","G93357A","G143708A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG087":["S213L"],"OPG088":["E124K"],"OPG113":["A543T"],"OPG165":["E65K"]},"labels":{"aa":"OPG087: S213L; OPG088: E124K; OPG113: A543T; OPG165: E65K"}}},{"name":"OP270027","node_attrs":{"div":65,"accession":"OP270027","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"strain":{"value":"MpxV/human/CAN/UN-NML-4024/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OP270027/2022-07-05"},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C65571T","G144988A","C156429T","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C181455T"],"OPG210":["Q34*"]},"labels":{"aa":"OPG210: Q34*"}}},{"name":"OP205115","node_attrs":{"div":62,"accession":"OP205115","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPXV_UK_2022_9000157"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP205115/2022-07-07"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-07"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C78232T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP422341","node_attrs":{"div":63,"accession":"OP422341","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"strain":{"value":"hMPXV/Austria/MUW1538395/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Austria/OP422341/2022-08-01"},"country":{"value":"Austria"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G28490A","G102694A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG044":["D134N"]},"labels":{"aa":"OPG044: D134N"}}},{"name":"OP415196","node_attrs":{"div":61,"accession":"OP415196","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPX_96X1Vd_9000218"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP415196/2022-03-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-03-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP555481","node_attrs":{"div":63,"accession":"OP555481","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0385/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555481/2022-07-11"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-11"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","C144301A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G151793C"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG165":["S262R"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG165: S262R"}}},{"name":"OP536815","node_attrs":{"div":61,"accession":"OP536815","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"9000453"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP536815/2022-09-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP642376","node_attrs":{"div":62,"accession":"OP642376","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain":{"value":"ANT-LDSP-ANT-MPX-24592-C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP642376/2022-09-07"},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-09-07"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C144256T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP628489","node_attrs":{"div":65,"accession":"OP628489","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-092175/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP628489/2022-09-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["A93217G","G116130A","G151339A","G152202A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["K496R"]},"labels":{"aa":"OPG113: K496R"}}},{"name":"OP605580","node_attrs":{"div":62,"accession":"OP605580","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain":{"value":"Slovenia-MPXV-39-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Slovenia/OP605580/2022-08-XX"},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-607T","C179082T","C179091T","T179094A","C179100T","T179103A","C179109T","T179112A","C179118T","T179121A","C179127T","T179130A","C179136T","C179145T","T179148A","C179154T","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179239A","-179240T","-179241A","-179242T","-179243A","G189288A"]}}},{"name":"OP594200","node_attrs":{"div":64,"accession":"OP594200","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI436"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP594200/2022-09-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G58518A","G59922A","G112249A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG131":["E104K"]},"labels":{"aa":"OPG131: E104K"}}},{"name":"OP837473","node_attrs":{"div":67,"accession":"OP837473","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"strain":{"value":"VAC_INS_MPX_1054_L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP837473/2022-10-25"},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-10-25"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C33082T","C36405T","C40849T","G68103A","G117233A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C180361T","A197043-","T197044-","G197045-"],"OPG049":["D24N"],"OPG055":["A227T"],"OPG060":["E112K"]},"labels":{"aa":"OPG049: D24N; OPG055: A227T; OPG060: E112K"}}},{"name":"OP693649","node_attrs":{"div":63,"accession":"OP693649","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"strain":{"value":"ANT_INS_MPX_0039_L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP693649/2022-07-29"},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-07-29"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["A2840-","T2841-","C2842-","G127058A","G136194A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","T196865-","A196866-","G196867-"],"OPG148":["R358K"],"OPG153":["H492Y"]},"labels":{"aa":"OPG148: R358K; OPG153: H492Y"}}},{"name":"OQ451900","node_attrs":{"div":62,"accession":"OQ451900","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI715"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ451900/2022-10-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-607T","G21655A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG037":["S260L"]},"labels":{"aa":"OPG037: S260L"}}},{"name":"OQ427152","node_attrs":{"div":63,"accession":"OQ427152","author":{"author":"Gigante,C.,Johnson,S.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Weigand,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Riner,D.,Li,Y.","value":"Gigante,C.,Johnson,S.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Weigand,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Riner,D.,Li,Y."},"strain":{"value":"MPXV_USA_2022_MI0008"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ427152/2022-11-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-11-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G1205A","C66878T","G70988A","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","C196005T","-196615A","-196616A","-196617A"],"OPG001":["S124L"],"OPG001_dup":["S124L"],"OPG085":["D552N"],"OPG089":["D375N"]},"labels":{"aa":"OPG001: S124L; OPG001_dup: S124L; OPG085: D552N; OPG089: D375N"}}},{"name":"OQ411312","node_attrs":{"div":62,"accession":"OQ411312","author":{"author":"Laubscher,F.,Chudzinsk,V.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinsk,V.,Schibler,M.,Kaiser,L.,Renzoni,A."},"strain":{"value":"hMPXV-CH-38292866/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Switzerland/OQ411312/2022-06-08"},"country":{"value":"Switzerland"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"date":{"value":"2022-06-08"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C87764T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG109":["E562K"]},"labels":{"aa":"OPG109: E562K"}}},{"name":"OQ503844","node_attrs":{"div":64,"accession":"OQ503844","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00468/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ503844/2023-01-26"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-01-26"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-607T","C6310T","A39482C","C81194T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A170123-","T170124-","A170125-","A170126-","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-","A181373-","T181374-","C181375-","T181376-","C181377-","T181378-","G181379-","G181380-","C181381-","T181382-","A181383-","T181384-","A181385-","T181386-","A181387-","T181388-","C181389-","T181390-","T181391-","A181392-","C181393-","G181394-","G181395-","T181396-","G181397-","A181398-","C181399-","A181400-","T181401-","G181402-","T181403-","T181404-","C181405-","G181406-","T181407-","G181408-","G181409-","T181410-","G181411-","T181412-","T181413-","A181414-","T181415-","G181416-","A181417-","A181418-","A181419-","C181420-","A181421-","T181422-","G181423-","T181424-","A181425-","T181426-","G181427-","A181428-","G181429-","A181430-","A181431-","A181432-","A181433-","A181434-","C181435-","T181436-","G181437-","C181438-","G181439-","T181440-","T181441-","G181442-","T181443-","A181444-","T181445-","C181446-","A181447-","T181448-","G181449-","A181450-","C181451-","G190900A"],"OPG016":["R164K"],"OPG057":["H238Q"],"OPG198":["K30-"]},"labels":{"aa":"OPG016: R164K; OPG057: H238Q; OPG198: K30-"}}},{"name":"OR035709","node_attrs":{"div":62,"accession":"OR035709","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_103"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR035709/2022-10-28"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188946T"]}}},{"name":"OR035700","node_attrs":{"div":61,"accession":"OR035700","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_94"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR035700/2022-07-27"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-27"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-"]}}},{"name":"OQ973329","node_attrs":{"div":63,"accession":"OQ973329","author":{"author":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L.","value":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L."},"strain":{"value":"case6_skin"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OQ973329/2022-09-01"},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T606-","C28168T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","C147965T","C173474-","G173475-","A173476-","C173477-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","A180535-","A180536-","T180537-","A180538-","G180539-","C180540-","G180541-","T180542-","A180543-","T180544-","C180545-","T180546-","T180547-","A180548-","A196614-"],"OPG172":["S180F"]},"labels":{"aa":"OPG172: S180F"}}},{"name":"OQ918699","node_attrs":{"div":66,"accession":"OQ918699","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00488/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ918699/2023-02-20"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-02-20"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G66587A","G106113A","G143857A","C144237T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C189810T"],"OPG165":["S241L"]},"labels":{"aa":"OPG165: S241L"}}},{"name":"OQ918696","node_attrs":{"div":67,"accession":"OQ918696","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00485/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ918696/2023-03-11"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-03-11"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G30285A","G37487A","C71193T","G119839A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C161690T","C177865T","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T179244-"],"OPG047":["P304S"],"OPG137":["E80K"],"OPG188":["S32F"],"OPG205":["S737F"]},"labels":{"aa":"OPG047: P304S; OPG137: E80K; OPG188: S32F; OPG205: S737F"}}},{"name":"OQ773466","node_attrs":{"div":61,"accession":"OQ773466","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI847"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ773466/2022-07-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OQ672580","node_attrs":{"div":70,"accession":"OQ672580","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"strain":{"value":"MPXV/human/Taiwan/110-093354/2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Taiwan/OQ672580/2023-03-XX"},"country":{"value":"Taiwan"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"date":{"value":"2023-03-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T4795C","C39503G","G43620A","A44076G","G45563A","T69121C","T80764C","A130204G","A143123G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG057":["K231N"],"OPG064":["F608S"],"OPG087":["Y89H"],"OPG104":["N86D"],"OPG164":["T116A"]},"labels":{"aa":"OPG057: K231N; OPG064: F608S; OPG087: Y89H; OPG104: N86D; OPG164: T116A"}}},{"name":"OQ627927","node_attrs":{"div":64,"accession":"OQ627927","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"strain":{"value":"INMI-18982022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Italy/OQ627927/2022-08-16"},"country":{"value":"Italy"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"date":{"value":"2022-08-16"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C45203T","C88917T","C130606T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OQ581849","node_attrs":{"div":63,"accession":"OQ581849","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0007b/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Spain/OQ581849/2022-07-05"},"country":{"value":"Spain"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["A52777C","C150418T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T169409C","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG071":["Y554*"]},"labels":{"aa":"OPG071: Y554*"}}},{"name":"OR264422","node_attrs":{"div":63,"accession":"OR264422","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain":{"value":"46_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Australia/OR264422/2022-07-13"},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-13"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["A41660-","A41661-","T41662-","T41663-","T41664-","G41665-","T41666-","T41667-","T41668-","T41669-","A41670-","C41671-","T41672-","C41673-","T41674-","A41675-","T41676-","C66963T","C118161T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG061":["R71-","V72-","K73-","Q74-","I75-"],"OPG136":["R476Q"]},"labels":{"aa":"OPG061: R71-, V72-, K73-, Q74-, I75-; OPG136: R476Q"}}},{"name":"OR264409","node_attrs":{"div":62,"accession":"OR264409","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain":{"value":"39_L"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Australia/OR264409/2022-05-19"},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C66718T","T179244-"],"OPG084":["S666L"]},"labels":{"aa":"OPG084: S666L"}}},{"name":"OR086992","node_attrs":{"div":66,"accession":"OR086992","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_183/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR086992/2022-08-03"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-03"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C23567T","C39608T","G67527A","G128816A","G145728A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OX291780","node_attrs":{"div":63,"accession":"OX291780","strain":{"value":"RNA"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Slovakia/OX291780/2022-07-25"},"country":{"value":"Slovakia"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"date":{"value":"2022-07-25"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T606-","G67955A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A173316-","T173317-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G184141A","A196614-"],"OPG085":["P193S"],"OPG210":["G929D"]},"labels":{"aa":"OPG085: P193S; OPG210: G929D"}}},{"name":"OX336038","node_attrs":{"div":62,"accession":"OX336038","strain":{"value":"RNA"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Slovakia/OX336038/2022-08-31"},"country":{"value":"Slovakia"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"date":{"value":"2022-08-31"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T606-","C28887T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG045":["E126K"]},"labels":{"aa":"OPG045: E126K"}}},{"name":"ON649879","node_attrs":{"div":61,"accession":"ON649879","author":{"author":"Israeli,O.,Guedj-Dana,Y.,Lazar,S.,Shifman,O.,Erez,N.,Weiss,S.,Paran,N.,Israely,T.,Schuster,O.,Zvi,A.,Beth-Din,A.,Cohen Gihon,I.","value":"Israeli,O.,Guedj-Dana,Y.,Lazar,S.,Shifman,O.,Erez,N.,Weiss,S.,Paran,N.,Israely,T.,Schuster,O.,Zvi,A.,Beth-Din,A.,Cohen Gihon,I."},"strain":{"value":"MPXV_ISR001_2022"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Israel/ON649879/2022-05-20"},"country":{"value":"Israel"},"institution":{"value":"Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel"},"date":{"value":"2022-05-20"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP382482","node_attrs":{"div":61,"accession":"OP382482","author":{"author":"Colson,P.","value":"Colson,P."},"strain":{"value":"hMPXV-IHU00005"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"France/OP382482/2022-07-04"},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-04"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP764621","node_attrs":{"div":61,"accession":"OP764621","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI563"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP764621/2022-06-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP205069","node_attrs":{"div":61,"accession":"OP205069","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPXV_UK_2022_9000063"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP205069/2022-06-06"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-06"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON631241","node_attrs":{"div":61,"accession":"ON631241","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain":{"value":"2022/2 SLO"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Slovenia/ON631241/2022-05-24"},"country":{"value":"Slovenia"},"institution":{"value":"Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia"},"date":{"value":"2022-05-24"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035663","node_attrs":{"div":61,"accession":"OR035663","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_57"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR035663/2022-06-09"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-06-09"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON563414","node_attrs":{"div":61,"accession":"ON563414","author":{"author":"Gigante,C.M.,Smole,S.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Brown,C.,Li,Y.","value":"Gigante,C.M.,Smole,S.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Brown,C.,Li,Y."},"strain":{"value":"MPXV_USA_2022_MA001"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/ON563414/2022-05-XX"},"country":{"value":"USA"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON755040","node_attrs":{"div":61,"accession":"ON755040","author":{"author":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O.","value":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O."},"strain":{"value":"MPXV_IRBA22-14"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"France/ON755040/2022-05-20"},"country":{"value":"France"},"institution":{"value":"IRBA, D.DNRBC/D.2MI/U.BACT"},"date":{"value":"2022-05-20"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000036","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C187154T"]}},"children":[{"name":"ON568298","node_attrs":{"div":62,"accession":"ON568298","author":{"author":"Antwerpen,M.H.,Lang,D.,Zange,S.,Walter,M.C.,Woelfel,R.","value":"Antwerpen,M.H.,Lang,D.,Zange,S.,Walter,M.C.,Woelfel,R."},"strain":{"value":"MPXV-BY-IMB25241"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/ON568298/2022-05-19"},"country":{"value":"Germany"},"institution":{"value":"Microbiol Genomics & Bioinformatics, Bundeswehr Institute of Microbiology, Germany"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"]}}},{"name":"ON927243","node_attrs":{"div":62,"accession":"ON927243","author":{"author":"Palomino-Cabrera,R.,Penas-Utrilla,D.,Buenestado-Serrano,S.,Perez-Lago,L.,Herranz Martin,M.,Veintimilla,C.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Palomino-Cabrera,R.,Penas-Utrilla,D.,Buenestado-Serrano,S.,Perez-Lago,L.,Herranz Martin,M.,Veintimilla,C.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"strain":{"value":"MpxV/Spain/MD-HGUGM-6642566/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Spain/ON927243/2022-06-21"},"country":{"value":"Spain"},"institution":{"value":"HGUGM, Microbial Genomics"},"date":{"value":"2022-06-21"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-"]}}}]},{"name":"NODE_0000037","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-607T","C144546T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"],"OPG166":["S50F"]},"labels":{"aa":"OPG166: S50F"}},"children":[{"name":"OP019275","node_attrs":{"div":64,"accession":"OP019275","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"strain":{"value":"hMPXV/Austria/MUW1525179/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Austria/OP019275/2022-06-10"},"country":{"value":"Austria"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"date":{"value":"2022-06-10"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","A107070C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G190319A","-196616A","-196617A"]}}},{"name":"OR473631","node_attrs":{"div":62,"accession":"OR473631","author":{"author":"Kwasiborski,A.,Hourdel,V.,Baliere,C.,Hoinard,D.,Grassin,Q.,Feher,M.,De La Porte Des Vaux,C.,Cresta,M.,Vanhomwegen,J.,Manuguerra,J.-C.,Batejat,C.,Caro,V.","value":"Kwasiborski,A.,Hourdel,V.,Baliere,C.,Hoinard,D.,Grassin,Q.,Feher,M.,De La Porte Des Vaux,C.,Cresta,M.,Vanhomwegen,J.,Manuguerra,J.-C.,Batejat,C.,Caro,V."},"strain":{"value":"CIBU-220031"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"France/OR473631/2022-06-03"},"country":{"value":"France"},"institution":{"value":"Insitut Pasteur, Environment and Infectious Risks Unit"},"date":{"value":"2022-06-03"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A"]}}}]},{"name":"NODE_0000038","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C103417T","C173114T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG123":["E552K"]},"labels":{"aa":"OPG123: E552K"}},"children":[{"name":"OP628472","node_attrs":{"div":63,"accession":"OP628472","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-087291/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP628472/2022-08-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{}}},{"name":"OQ503776","node_attrs":{"div":66,"accession":"OQ503776","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-107595/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ503776/2022-10-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C29887T","C90945T","G175189A"],"OPG204":["D220N"]},"labels":{"aa":"OPG204: D220N"}}}]},{"name":"NODE_0000039","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G70190A","T179244-","T179247-","T179248-","A179249-","T179250-","T179251-","T179253-","T179254-","T179255-","T179258-","T179260-","A179261-","T179262-","A179266-","T179267-"],"OPG089":["E109K"]},"labels":{"aa":"OPG089: E109K"}},"children":[{"name":"OQ159052","node_attrs":{"div":62,"accession":"OQ159052","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI657"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ159052/2022-08-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","C179245-","G179246-","G179252-","G179256-","G179257-","C179259-","G179263-","C179264-","C179265-"]}}},{"name":"OR759158","node_attrs":{"div":66,"accession":"OR759158","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain":{"value":"hMpxV/Canada/ON-PHOL067/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OR759158/2022-08-01"},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G4454A","G6619A","G24622A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179244T","-179247T","-179248T","-179249A","-179250T","-179251T","-179253T","-179254T","-179255T","-179258T","-179260T","-179261A","-179262T","-179266A","-179267T","C190323T","C192756T"],"OPG003":["H52Y"],"OPG003_dup":["H52Y"],"OPG040":["S286L"]},"labels":{"aa":"OPG003: H52Y; OPG003_dup: H52Y; OPG040: S286L"}}}]},{"name":"NODE_0000040","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C34784T","C101418T","G109844A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG054":["D405N"],"OPG120":["D111N"]},"labels":{"aa":"OPG054: D405N; OPG120: D111N"}},"children":[{"name":"OR743494","node_attrs":{"div":64,"accession":"OR743494","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2023/ON/RKI1025"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OR743494/2023-09-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2023-09-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G179263-","C179264-"]}}},{"name":"OR743498","node_attrs":{"div":67,"accession":"OR743498","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2023/ON/RKI1029"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OR743498/2023-10-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2023-10-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C45528T","C84767T","C170791T"],"OPG064":["R124K"]},"labels":{"aa":"OPG064: R124K"}}}]},{"name":"NODE_0000042","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C77462T","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG098":["S188F"]},"labels":{"aa":"OPG098: S188F"}},"children":[{"name":"OP225968","node_attrs":{"div":62,"accession":"OP225968","author":{"author":"Gigante,C.M.,Hauser,J.R.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y.","value":"Gigante,C.M.,Hauser,J.R.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y."},"strain":{"value":"MPXV_USA_2022_DC0005"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP225968/2022-06-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C179145-"]}}},{"name":"OP440545","node_attrs":{"div":62,"accession":"OP440545","author":{"author":"Hemarajata,P.,Green,N.M.","value":"Hemarajata,P.,Green,N.M."},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00044/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP440545/2022-07-22"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-07-22"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-"]}}},{"name":"OR759186","node_attrs":{"div":65,"accession":"OR759186","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain":{"value":"hMpxV/Canada/ON-PHOL098/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OR759186/2022-09-01"},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C111164T","A143676G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C152385T","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"],"OPG130":["E247K"],"OPG165":["N54S"]},"labels":{"aa":"OPG130: E247K; OPG165: N54S"}}}]},{"name":"NODE_0000043","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C112408T"],"OPG131":["L157F"]},"labels":{"aa":"OPG131: L157F"}},"children":[{"name":"OQ672571","node_attrs":{"div":64,"accession":"OQ672571","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"strain":{"value":"19012023_anal"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OQ672571/2023-01-19"},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2023-01-19"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G69989A","C117978T","T145510-","T145511-","A145512-","C145513-","T145514-","T145515-","A145516-","A145517-","T145518-","A145519-","G145520-","A145521-","T145522-","T145523-","A145524-","T145525-","G145526-","T145527-","T146786-","A146787-","T146788-","T146789-","G146790-","T146791-","T146792-","A146793-","T146794-","C146795-","G146796-","T146797-","A146798-","A146799-","T146800-","T146801-","G146802-","G146803-","A146804-","A146805-","A146806-","A146807-","T146808-","T146809-","G146810-","G146811-","T146812-","A146813-","T146814-","T146815-","C146816-","A146817-","A146818-","G146819-","T146820-","G146821-","A146822-","G146823-","C146824-","T146825-","G146826-","G146827-","A146828-","T146829-","T146830-","A146831-","T146832-","G146833-","T146834-","G146835-","A146836-","G146837-","T146838-","A146839-","T146840-","T146841-","G146842-","G146843-","A146844-","T146845-","T146846-","G146847-","T146848-","A146849-","T146850-","A146851-","T146852-","T146853-","T146854-","T146855-","A146856-","T146857-","T146858-","T146859-","T146860-","A146861-","T146862-","A146863-","T146864-","T146865-","T146866-","T146867-","A146868-","T146869-","A146870-","T146871-","T146872-","T146873-","T146874-","A146875-","T146876-","A146877-","T146878-","T146879-","T146880-","T146881-","A146882-","T146883-","T146884-","T146885-","T146886-","A146887-","T146888-","A146889-","T146890-","T146891-","T146892-","T146893-","A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","G146913-","T146914-","A146915-","G146916-","T146917-","A146918-","A146919-","G146920-","A146921-","A146922-","T146923-","A146924-","G146925-","A146926-","A146927-","T146928-","G146929-","C146930-","T146931-","A146932-","A146933-","T146934-","G146935-","T146936-","C146937-","A146938-","A146939-","G146940-","T146941-","T146942-","T146943-","A146944-","T146945-","T146946-","C146947-","G146948-","A146949-","A146950-","T146951-","A146952-","G146953-","A146954-","T146955-","G146956-","T146957-","C146958-","T146959-","T146960-","A146961-","T146962-","T146963-","A146964-","A146965-","A146966-","A146967-","A146968-","A146969-","C146970-","A146971-","T146972-","A146973-","T146974-","A146975-","T146976-","A146977-","A146978-","T146979-","A146980-","A146981-","A146982-","T146983-","A146984-","A146985-","C146986-","A146987-","A146988-","T146989-","G146990-","G146991-","C146992-","T146993-","G146994-","A146995-","A146996-","T146997-","G146998-","G146999-","C147000-","A147001-","T147002-","A147003-","A147004-","A147005-","A147006-","T147007-","T147008-","A147009-","T147010-","C147011-","G147012-","A147013-","G147014-","G147015-","A147016-","T147017-","A147018-","T147019-","C147020-","T147021-","C147022-","A147023-","A147024-","A147025-","A147026-","A147027-","T169726-","A169727-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG089":["A42T"],"OPG136":["R537K"],"OPG197":["T20-"]},"labels":{"aa":"OPG089: A42T; OPG136: R537K; OPG197: T20-"}}},{"name":"NODE_0000044","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G47746-","A62110-","T62111-","A62112-","A62113-","A62114-","A62116-","T62118-","T62121-","A62122-","T62123-","A62124-","T62125-","A62126-","T62127-","T62128-","T62129-","A62131-","A62132-","A62133-","A62134-","T62135-","T62138-","T62139-","A62140-","T62144-","T62145-","A62148-","T62149-","T62150-","A62151-","A62167-","T62168-","T62169-","T62171-","A62173-","A62174-","T62175-","A62176-","T62177-","A62178-","T62179-","A62181-","T62182-","T62183-","A62184-","A62187-","T62188-","T62189-","T62190-","A62191-","A62192-","T62194-","T62197-","T62198-","A62200-","T62202-","A62203-","T62204-","A62206-","T62207-","T62213-","A62217-","A62219-","A62220-","A62221-","T62222-","T62223-","A62224-","A62227-","T62228-","A62230-","A62231-","A62232-","A62233-","A62236-","T62237-","T62238-","A62239-","A62240-","T62241-","A62242-","A62244-","T62246-","T62247-","A62248-","T62249-","A62252-","A62254-","T62255-","A62259-","T62261-","T62262-","A62263-","A62265-","A62266-","T62270-","T62271-","A62272-","T62273-","A62274-","A62277-","T62278-","A62281-","A62284-","T62285-","T62286-","T62287-","A62288-","T62289-","A62290-","T62291-","T62293-","A62294-","A62295-","A62296-","A62297-","A62298-","T62299-","T62300-","A62301-","A62303-","T62304-","A62306-","A62307-","A62308-","A62310-","A62311-","T62312-","A62313-","T62314-","T62316-","A62318-","A62320-","A62321-","T62324-","T62327-","A62328-","T62330-","T62331-","T62333-","A62334-","T62335-","A62336-","T62338-","A62340-","A62342-","A62343-","T62344-","T62345-","A62347-","A62350-","A62351-","A62352-","A62354-","A62355-","T62356-","T62358-","T62359-","T62360-","T62362-","T62363-","A62364-","A62366-","T62367-","A62368-","T62369-","T62370-","T62371-","T62372-","T62373-","T62374-","T62375-","T62377-","T62378-","A62379-","T62380-","T62381-","A62382-","T62384-","A62385-","A62386-","A62390-","T62392-","T62393-","A62394-","A62395-","T62396-","A62397-","T62399-","A62400-","A62403-","A62404-","T62406-","A62409-","A62410-","A62411-","A62412-","T62414-","A62415-","A62417-","T62419-","T62420-","A62422-","T62423-","T62424-","A62425-","T62426-","T62427-","T62429-","A62430-","T62431-","A62432-","A62433-","T62435-","A62436-","T62437-","A62438-","A62440-","T62441-","A62442-","T62446-","T62447-","A62450-","A62451-","A62452-","T62453-","A62454-","A62455-","T62456-","T62458-","T62459-","T62461-","T62463-","T62464-","T62465-","A62467-","T62468-","A62469-","A62470-","A62471-","A62472-","T62474-","T62475-","A62478-","A62480-","A62481-","A62482-","A62483-","T62484-","T62486-","A62487-","A62489-","A62490-","T62491-","T62492-","T62493-","T62494-","T62495-","T62496-","A62497-","A62498-","A62499-","A62500-","A62501-","T62503-","T62504-","A62505-","T62506-","T62508-","T62509-","T62510-","T62511-","T62514-","A62515-","T62516-","T62517-","A62518-","T62520-","A62521-","A62522-","T62523-","A62524-","T62525-","T62528-","T62531-","T62532-","A62533-","A62535-","T62539-","T62540-","A62541-","T62542-","T62543-","A62544-","T62545-","T62546-","A62547-","A62548-","T62549-","A62550-","T62551-","A62553-","T62555-","A62557-","T62558-","A62560-","A62561-","A62562-","T62563-","A62566-","A62568-","T62573-","T62574-","T62576-","A62577-","A62579-","T62580-","A62581-","T62582-","T62586-","T62587-","T62588-","T62589-","A62590-","T62591-","T62592-","T62593-","A62596-","A62598-","T62599-","T62600-","A62601-","A62603-","T62604-","T62607-","A62608-","A62609-","A62610-","T62611-","A62614-","A62615-","T62616-","A62617-","T62619-","A62621-","A62622-","A62623-","T62625-","A62626-","T62627-","T62629-","T62630-","A62703-","T62704-","A62705-","A62706-","A62707-","A62709-","A62710-","T62711-","T62712-","T62713-","A62715-","A62717-","A62718-","A62719-","T62720-","A62723-","T62724-","T62726-","T62727-","A62728-","A62729-","T62730-","T62732-","A62733-","T62734-","T62735-","A62736-","T62738-","A62739-","A62742-","A62743-","A62744-","T62745-","T62746-","T62747-","T62748-","T62749-","T62750-","A62752-","T62756-","A62757-","T62759-","A62762-","A62763-","T62764-","T62765-","A62767-","A62768-","A62770-","T62771-","T62772-","T62774-","A62775-","A62776-","T62777-","A62780-","T62781-","A62783-","T62784-","T62786-","T62787-","T62789-","A62790-","T62793-","A62794-","T62795-","T62796-","T62797-","A62799-","T62800-","A62804-","T62805-","A62806-","A62807-","A62809-","T62810-","T62812-","T62813-","A62814-","A62815-","T62816-","T62817-","T62818-","A62821-","A62822-","T62823-","A62824-","A62827-","A62828-","T62832-","T62833-","T62834-","T62835-","A62836-","A62837-","T62838-","A62839-","T62840-","T62841-","T62842-","A62845-","T62846-","A62848-","T62849-","A62850-","T62851-","A62852-","T62856-","A62857-","T62859-","T62861-","C62862-","T62863-","T62865-","T62866-","T62867-","A62871-","T62873-","T62874-","A62875-","T62876-","A62877-","T62878-","A62879-","T62882-","T62883-","A62884-","T62885-","T62886-","A62889-","A62891-","A62892-","T62893-","A62894-","A62897-","T62899-","A62901-","T62902-","T62903-","A62904-","T62905-","A62906-","T62907-","A62908-","T62910-","A62913-","A62914-","A62915-","A62916-","A62917-","A62918-","A62920-","A62921-","A62922-","A62923-","T62924-","A62925-","A62926-","T62928-","A62929-","T62931-","A62932-","T62933-","A62934-","A62935-","A62936-","A62937-","T62938-","T62940-","T62942-","A62943-","T62944-","A62947-","A62948-","T62949-","A62953-","A62954-","A62955-","A62956-","A62957-","A62960-","A62961-","A62962-","T62963-","T62964-","A62965-","T62966-","A62969-","T62970-","A62971-","T62972-","A62973-","T62976-","A62977-","T62978-","A62979-","A62981-","A62982-","T62983-","A62988-","A62989-","A62991-","T62992-","T62993-","A62995-","A62996-","T62999-","A63000-","T63001-","T63002-","A63003-","A63004-","T63005-","A63006-","T63008-","T63009-","A63010-","A63011-","T63012-","T63013-","T63015-","T63016-","T63017-","T63018-","T63019-","A63021-","T63023-","T63026-","A63027-","A63028-","A63030-","A63031-","A63035-","T63036-","A63037-","T63040-","T63041-","A63042-","T63043-","T63044-","A63046-","A63048-","T63049-","T63050-","T63052-","A63053-","T63054-","T63057-","T63058-","T63059-","T63060-","A63061-","A63062-","A63063-","T63064-","A63065-","T63066-","T63067-","T63069-","A63070-","T63071-","A63072-","A63073-","T63075-","T63076-","A63078-","A63080-","T63082-","T63083-","A63085-","T63086-","A63087-","A63089-","T63090-","A63091-","T63092-","T63093-","A63094-","A63095-","T63096-","A63098-","A63101-","A63102-","T63103-","T63104-","A63106-","A63107-","A63108-","A63109-","T63110-","T63111-","A63112-","T63113-","T63114-","T63115-","T63116-","T63117-","A63118-","T63119-","A63121-","A63124-","T63127-","T63129-","T63131-","T63132-","T63133-","A63135-","A63138-","T63139-","A63141-","T63142-","T63145-","A63148-","A63153-","T63155-","T63156-","A63157-","A63158-","A63161-","A63162-","A63166-","A63167-","T63168-","A63171-","T63173-","A63174-","A63175-","A63176-","A63177-","T63178-","A63179-","A63180-","A63181-","T63182-","A63183-","T63184-","A63186-","T63187-","T63188-","A63189-","A63190-","T63191-","A63192-","T63193-","A63194-","T63195-","T63198-","T63200-","A63201-","A63203-","T63204-","A63205-","T63206-","T63207-","A63208-","T63210-","A63211-","T63212-","T63213-","T63214-","T63215-","T63216-","A63217-","T63218-","T63219-","A63220-","A63221-","T63222-","T63225-","T63226-","T63227-","A63229-","T63230-","T63231-","A63232-","T63233-","A63235-","T63236-","T63238-","T63239-","T63241-","T63244-","A63245-","A63250-","A63251-","T63252-","A63254-","T63255-","T63256-","A63259-","T63260-","A63262-","T63263-","A63265-","A63266-","A63268-","T63270-","A63272-","T63273-","T63274-","T63275-","A63277-","A63279-","A63280-","A63282-","T63283-","T63286-","A63291-","T63293-","A63294-","T63295-","T63296-","A63297-","A63298-","T63299-","T63303-","T63304-","T63305-","A63306-","T63308-","A63309-","A63310-","A63311-","A63313-","T63315-","A63318-","T63319-","T63322-","T63323-","A63326-","A63327-","T63328-","A63329-","A63330-","T63331-","A63332-","A63333-","A63334-","A63335-","T63337-","T63338-","T63340-","A63343-","A63344-","T63346-","T63347-","A63348-","A63349-","A63350-","A63353-","T63354-","A63355-","T63356-","T63357-","A63358-","T63359-","A63362-","T63363-","T63364-","T63367-","T63368-","T63369-","A63370-","A63371-","A63372-","A63374-","T63375-","A63376-","T63377-","A63379-","T63382-","A63384-","T63385-","T63387-","A63388-","A63389-","A63393-","A63395-","A63397-","A63398-","T63399-","T63400-","T63401-","T63402-","T63403-","T63404-","T63407-","A63408-","T63411-","T63412-","T63413-","T63414-","A63415-","A63417-","A63419-","T63421-","T63422-","T63423-","A63425-","A63426-","T63429-","A63430-","T63432-","T63433-","T63435-","T63436-","T63437-","A63438-","A63439-","A63441-","A63442-","A63443-","T63445-","T63446-","A63447-","T63448-","T63449-","A63451-","T63452-","T63455-","T63458-","T63460-","A63461-","T63463-","A63464-","T63465-","T63466-","T63468-","A63469-","T63470-","T63471-","T63472-","A63473-","A63474-","T63475-","T63476-","T63477-","T63478-","T63480-","A63481-","T63483-","T63484-","A63485-","A63486-","T63487-","T63488-","T63489-","A63490-","T63491-","A63493-","A63495-","T63496-","A63497-","T63498-","A63500-","A63502-","T63503-","T63504-","C89166T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"]}},"children":[{"name":"OQ672574","node_attrs":{"div":66,"accession":"OQ672574","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"strain":{"value":"02022023_anal"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OQ672574/2023-02-02"},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2023-02-02"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-62110A","-62111T","-62112A","-62113A","-62114A","-62116A","-62118T","-62121T","-62122A","-62123T","-62124A","-62125T","-62126A","-62127T","-62128T","-62129T","-62131A","-62132A","-62133A","-62134A","-62135T","-62138T","-62139T","-62140A","-62144T","-62145T","-62148A","-62149T","-62150T","-62151A","-62167A","-62168T","-62169T","-62171T","-62173A","-62174A","-62175T","-62176A","-62177T","-62178A","-62179T","-62181A","-62182T","-62183T","-62184A","-62187A","-62188T","-62189T","-62190T","-62191A","-62192A","-62194T","-62197T","-62198T","-62200A","-62202T","-62203A","-62204T","-62206A","-62207T","-62213T","-62217A","-62219A","-62220A","-62221A","-62222T","-62223T","-62224A","-62227A","-62228T","-62230A","-62231A","-62232A","-62233A","-62236A","-62237T","-62238T","-62239A","-62240A","-62241T","-62242A","-62244A","-62246T","-62247T","-62248A","-62249T","-62252A","-62254A","-62255T","-62259A","-62261T","-62262T","-62263A","-62265A","-62266A","-62270T","-62271T","-62272A","-62273T","-62274A","-62277A","-62278T","-62281A","-62284A","-62285T","-62286T","-62287T","-62288A","-62289T","-62290A","-62291T","-62293T","-62294A","-62295A","-62296A","-62297A","-62298A","-62299T","-62300T","-62301A","-62303A","-62304T","-62306A","-62307A","-62308A","-62310A","-62311A","-62312T","-62313A","-62314T","-62316T","-62318A","-62320A","-62321A","-62324T","-62327T","-62328A","-62330T","-62331T","-62333T","-62334A","-62335T","-62336A","-62338T","-62340A","-62342A","-62343A","-62344T","-62345T","-62347A","-62350A","-62351A","-62352A","-62354A","-62355A","-62356T","-62358T","-62359T","-62360T","-62362T","-62363T","-62364A","-62366A","-62367T","-62368A","-62369T","-62370T","-62371T","-62372T","-62373T","-62374T","-62375T","-62377T","-62378T","-62379A","-62380T","-62381T","-62382A","-62384T","-62385A","-62386A","-62390A","-62392T","-62393T","-62394A","-62395A","-62396T","-62397A","-62399T","-62400A","-62403A","-62404A","-62406T","-62409A","-62410A","-62411A","-62412A","-62414T","-62415A","-62417A","-62419T","-62420T","-62422A","-62423T","-62424T","-62425A","-62426T","-62427T","-62429T","-62430A","-62431T","-62432A","-62433A","-62435T","-62436A","-62437T","-62438A","-62440A","-62441T","-62442A","-62446T","-62447T","-62450A","-62451A","-62452A","-62453T","-62454A","-62455A","-62456T","-62458T","-62459T","-62461T","-62463T","-62464T","-62465T","-62467A","-62468T","-62469A","-62470A","-62471A","-62472A","-62474T","-62475T","-62478A","-62480A","-62481A","-62482A","-62483A","-62484T","-62486T","-62487A","-62489A","-62490A","-62491T","-62492T","-62493T","-62494T","-62495T","-62496T","-62497A","-62498A","-62499A","-62500A","-62501A","-62503T","-62504T","-62505A","-62506T","-62508T","-62509T","-62510T","-62511T","-62514T","-62515A","-62516T","-62517T","-62518A","-62520T","-62521A","-62522A","-62523T","-62524A","-62525T","-62528T","-62531T","-62532T","-62533A","-62535A","-62539T","-62540T","-62541A","-62542T","-62543T","-62544A","-62545T","-62546T","-62547A","-62548A","-62549T","-62550A","-62551T","-62553A","-62555T","-62557A","-62558T","-62560A","-62561A","-62562A","-62563T","-62566A","-62568A","-62573T","-62574T","-62576T","-62577A","-62579A","-62580T","-62581A","-62582T","-62586T","-62587T","-62588T","-62589T","-62590A","-62591T","-62592T","-62593T","-62596A","-62598A","-62599T","-62600T","-62601A","-62603A","-62604T","-62607T","-62608A","-62609A","-62610A","-62611T","-62614A","-62615A","-62616T","-62617A","-62619T","-62621A","-62622A","-62623A","-62625T","-62626A","-62627T","-62629T","-62630T","-62703A","-62704T","-62705A","-62706A","-62707A","-62709A","-62710A","-62711T","-62712T","-62713T","-62715A","-62717A","-62718A","-62719A","-62720T","-62723A","-62724T","-62726T","-62727T","-62728A","-62729A","-62730T","-62732T","-62733A","-62734T","-62735T","-62736A","-62738T","-62739A","-62742A","-62743A","-62744A","-62745T","-62746T","-62747T","-62748T","-62749T","-62750T","-62752A","-62756T","-62757A","-62759T","-62762A","-62763A","-62764T","-62765T","-62767A","-62768A","-62770A","-62771T","-62772T","-62774T","-62775A","-62776A","-62777T","-62780A","-62781T","-62783A","-62784T","-62786T","-62787T","-62789T","-62790A","-62793T","-62794A","-62795T","-62796T","-62797T","-62799A","-62800T","-62804A","-62805T","-62806A","-62807A","-62809A","-62810T","-62812T","-62813T","-62814A","-62815A","-62816T","-62817T","-62818T","-62821A","-62822A","-62823T","-62824A","-62827A","-62828A","-62832T","-62833T","-62834T","-62835T","-62836A","-62837A","-62838T","-62839A","-62840T","-62841T","-62842T","-62845A","-62846T","-62848A","-62849T","-62850A","-62851T","-62852A","-62856T","-62857A","-62859T","-62863T","-62865T","-62866T","-62867T","-62871A","-62873T","-62874T","-62875A","-62876T","-62877A","-62878T","-62879A","-62882T","-62883T","-62884A","-62885T","-62886T","-62889A","-62891A","-62892A","-62893T","-62894A","-62897A","-62899T","-62901A","-62902T","-62903T","-62904A","-62905T","-62906A","-62907T","-62908A","-62910T","-62913A","-62914A","-62915A","-62916A","-62917A","-62918A","-62920A","-62921A","-62922A","-62923A","-62924T","-62925A","-62926A","-62928T","-62929A","-62931T","-62932A","-62933T","-62934A","-62935A","-62936A","-62937A","-62938T","-62940T","-62942T","-62943A","-62944T","-62947A","-62948A","-62949T","-62953A","-62954A","-62955A","-62956A","-62957A","-62960A","-62961A","-62962A","-62963T","-62964T","-62965A","-62966T","-62969A","-62970T","-62971A","-62972T","-62973A","-62976T","-62977A","-62978T","-62979A","-62981A","-62982A","-62983T","-62988A","-62989A","-62991A","-62992T","-62993T","-62995A","-62996A","-62999T","-63000A","-63001T","-63002T","-63003A","-63004A","-63005T","-63006A","-63008T","-63009T","-63010A","-63011A","-63012T","-63013T","-63015T","-63016T","-63017T","-63018T","-63019T","-63021A","-63023T","-63026T","-63027A","-63028A","-63030A","-63031A","-63035A","-63036T","-63037A","-63040T","-63041T","-63042A","-63043T","-63044T","-63046A","-63048A","-63049T","-63050T","-63052T","-63053A","-63054T","-63057T","-63058T","-63059T","-63060T","-63061A","-63062A","-63063A","-63064T","-63065A","-63066T","-63067T","-63069T","-63070A","-63071T","-63072A","-63073A","-63075T","-63076T","-63078A","-63080A","-63082T","-63083T","-63085A","-63086T","-63087A","-63089A","-63090T","-63091A","-63092T","-63093T","-63094A","-63095A","-63096T","-63098A","-63101A","-63102A","-63103T","-63104T","-63106A","-63107A","-63108A","-63109A","-63110T","-63111T","-63112A","-63113T","-63114T","-63115T","-63116T","-63117T","-63118A","-63119T","-63121A","-63124A","-63127T","-63129T","-63131T","-63132T","-63133T","-63135A","-63138A","-63139T","-63141A","-63142T","-63145T","-63148A","-63153A","-63155T","-63156T","-63157A","-63158A","-63161A","-63162A","-63166A","-63167A","-63168T","-63171A","-63173T","-63174A","-63175A","-63176A","-63177A","-63178T","-63179A","-63180A","-63181A","-63182T","-63183A","-63184T","-63186A","-63187T","-63188T","-63189A","-63190A","-63191T","-63192A","-63193T","-63194A","-63195T","-63198T","-63200T","-63201A","-63203A","-63204T","-63205A","-63206T","-63207T","-63208A","-63210T","-63211A","-63212T","-63213T","-63214T","-63215T","-63216T","-63217A","-63218T","-63219T","-63220A","-63221A","-63222T","-63225T","-63226T","-63227T","-63229A","-63230T","-63231T","-63232A","-63233T","-63235A","-63236T","-63238T","-63239T","-63241T","-63244T","-63245A","-63250A","-63251A","-63252T","-63254A","-63255T","-63256T","-63259A","-63260T","-63262A","-63263T","-63265A","-63266A","-63268A","-63270T","-63272A","-63273T","-63274T","-63275T","-63277A","-63279A","-63280A","-63282A","-63283T","-63286T","-63291A","-63293T","-63294A","-63295T","-63296T","-63297A","-63298A","-63299T","-63303T","-63304T","-63305T","-63306A","-63308T","-63309A","-63310A","-63311A","-63313A","-63315T","-63318A","-63319T","-63322T","-63323T","-63326A","-63327A","-63328T","-63329A","-63330A","-63331T","-63332A","-63333A","-63334A","-63335A","-63337T","-63338T","-63340T","-63343A","-63344A","-63346T","-63347T","-63348A","-63349A","-63350A","-63353A","-63354T","-63355A","-63356T","-63357T","-63358A","-63359T","-63362A","-63363T","-63364T","-63367T","-63368T","-63369T","-63370A","-63371A","-63372A","-63374A","-63375T","-63376A","-63377T","-63379A","-63382T","-63384A","-63385T","-63387T","-63388A","-63389A","-63393A","-63395A","-63397A","-63398A","-63399T","-63400T","-63401T","-63402T","-63403T","-63404T","-63407T","-63408A","-63411T","-63412T","-63413T","-63414T","-63415A","-63417A","-63419A","-63421T","-63422T","-63423T","-63425A","-63426A","-63429T","-63430A","-63432T","-63433T","-63435T","-63436T","-63437T","-63438A","-63439A","-63441A","-63442A","-63443A","-63445T","-63446T","-63447A","-63448T","-63449T","-63451A","-63452T","-63455T","-63458T","-63460T","-63461A","-63463T","-63464A","-63465T","-63466T","-63468T","-63469A","-63470T","-63471T","-63472T","-63473A","-63474A","-63475T","-63476T","-63477T","-63478T","-63480T","-63481A","-63483T","-63484T","-63485A","-63486A","-63487T","-63488T","-63489T","-63490A","-63491T","-63493A","-63495A","-63496T","-63497A","-63498T","-63500A","-63502A","-63503T","-63504T","C151552T","C167451T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","G187391A"],"OPG178":["S15F"]},"labels":{"aa":"OPG178: S15F"}}},{"name":"OQ672570","node_attrs":{"div":63,"accession":"OQ672570","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"strain":{"value":"02112022_anal"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OQ672570/2022-11-02"},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-11-02"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G49680-","G49710-","G62109-","G62115-","G62117-","C62119-","C62120-","G62130-","C62136-","G62137-","C62141-","G62142-","G62143-","C62146-","G62147-","C62166-","G62170-","G62172-","C62180-","G62185-","G62186-","C62193-","C62195-","C62196-","G62199-","C62201-","C62205-","G62208-","G62209-","C62210-","G62211-","G62212-","G62214-","C62215-","C62216-","G62218-","C62225-","C62226-","C62229-","G62234-","C62235-","C62243-","G62245-","G62250-","C62251-","G62253-","C62256-","G62257-","C62258-","G62260-","G62264-","C62267-","G62268-","G62269-","G62275-","C62276-","C62279-","C62280-","C62282-","C62283-","C62292-","G62302-","C62305-","G62309-","G62315-","G62317-","C62319-","C62322-","G62323-","C62325-","C62326-","G62329-","G62332-","C62337-","G62339-","G62341-","G62346-","C62348-","G62349-","C62353-","G62357-","C62361-","C62365-","C62376-","G62383-","C62387-","C62388-","G62389-","C62391-","G62398-","G62401-","G62402-","C62405-","G62407-","G62408-","C62413-","G62416-","C62418-","G62421-","C62428-","G62434-","G62439-","C62443-","C62444-","C62445-","C62448-","C62449-","G62457-","C62460-","C62462-","G62466-","G62473-","C62476-","C62477-","G62479-","G62485-","G62488-","G62502-","C62507-","G62512-","C62513-","C62519-","C62526-","G62527-","G62529-","G62530-","G62534-","C62536-","G62537-","C62538-","G62552-","G62554-","G62556-","G62559-","C62564-","C62565-","C62567-","C62569-","C62570-","G62571-","C62572-","C62575-","G62578-","C62583-","G62584-","C62585-","C62594-","C62595-","C62597-","G62602-","G62605-","G62606-","C62612-","C62613-","G62618-","G62620-","C62624-","C62628-","C62708-","C62714-","C62716-","G62721-","G62722-","G62725-","G62731-","G62737-","G62740-","G62741-","G62751-","C62753-","G62754-","C62755-","G62758-","G62760-","G62761-","G62766-","G62769-","C62773-","G62778-","G62779-","G62782-","G62785-","C62788-","C62791-","C62792-","C62798-","C62801-","C62802-","G62803-","C62808-","G62811-","C62819-","C62820-","C62825-","C62826-","C62829-","G62830-","G62831-","C62843-","G62844-","G62847-","C62853-","G62854-","G62855-","G62858-","C62860-","C62864-","C62868-","G62869-","G62870-","C62872-","G62880-","C62881-","C62887-","C62888-","C62890-","C62895-","G62896-","G62898-","C62900-","C62909-","C62911-","C62912-","C62919-","C62927-","G62930-","C62939-","G62941-","C62945-","G62946-","G62950-","G62951-","G62952-","C62958-","G62959-","C62967-","G62968-","G62974-","G62975-","G62980-","C62984-","C62985-","G62986-","G62987-","C62990-","G62994-","C62997-","G62998-","C63007-","C63014-","C63020-","G63022-","G63024-","G63025-","G63029-","C63032-","C63033-","G63034-","G63038-","G63039-","G63045-","C63047-","G63051-","G63055-","G63056-","C63068-","C63074-","G63077-","G63079-","C63081-","G63084-","G63088-","G63097-","C63099-","G63100-","G63105-","C63120-","C63122-","C63123-","C63125-","G63126-","G63128-","G63130-","C63134-","G63136-","G63137-","C63140-","C63143-","G63144-","C63146-","G63147-","C63149-","G63150-","C63151-","C63152-","G63154-","C63159-","C63160-","C63163-","C63164-","G63165-","G63169-","G63170-","G63172-","C63185-","G63196-","C63197-","C63199-","G63202-","G63209-","C63223-","C63224-","G63228-","C63234-","C63237-","C63240-","C63242-","G63243-","C63246-","G63247-","C63248-","G63249-","G63253-","C63257-","C63258-","G63261-","C63264-","G63267-","G63269-","G63271-","G63276-","G63278-","C63281-","C63284-","C63285-","C63287-","C63288-","G63289-","G63290-","G63292-","G63300-","G63301-","G63302-","G63307-","C63312-","G63314-","C63316-","C63317-","C63320-","G63321-","G63324-","C63325-","G63336-","G63339-","C63341-","C63342-","G63345-","G63351-","G63352-","G63360-","C63361-","C63365-","G63366-","G63373-","C63378-","C63380-","C63381-","C63383-","C63386-","C63390-","G63391-","G63392-","G63394-","C63396-","G63405-","G63406-","G63409-","G63410-","G63416-","G63418-","C63420-","G63424-","G63427-","C63428-","C63431-","G63434-","C63440-","G63444-","C63450-","C63453-","G63454-","C63456-","G63457-","C63459-","C63462-","C63467-","G63479-","G63482-","C63492-","C63494-","C63499-","C63501-"],"OPG068":["D494-"],"OPG081":["N46-","R47-","T48-","V49-","T50-","I51-","F52-","K53-","Y54-","I55-","G56-","L57-","F58-","I59-"]},"labels":{"aa":"OPG068: D494-; OPG081: N46-, R47-, T48-, V49-, T50-, I51-, F52-, K53-, Y54-, I55-, G56-, L57-, F58-, I59-"}}}]}]},{"name":"NODE_0000045","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.16"}},"branch_attrs":{"mutations":{"nuc":["C9389T","C30154T","G161797A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","A185557C"],"OPG188":["E68K"],"OPG210":["K1401T"]},"labels":{"aa":"OPG188: E68K; OPG210: K1401T","clade":"B.1.16"}},"children":[{"name":"OP459211","node_attrs":{"div":66,"accession":"OP459211","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain":{"value":"ANT-LDSP-ANT-MPX-23596-O"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP459211/2022-08-29"},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"date":{"value":"2022-08-29"},"lineage":{"value":"B.1.16"}},"branch_attrs":{"mutations":{"nuc":["G170076A"]}}},{"name":"OP642383","node_attrs":{"div":67,"accession":"OP642383","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain":{"value":"ANT-LDSP-ANT-MPX-24909-C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP642383/2022-09-09"},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-09-09"},"lineage":{"value":"B.1.16"}},"branch_attrs":{"mutations":{"nuc":["G6863A","C132608T"]}}},{"name":"OP693647","node_attrs":{"div":65,"accession":"OP693647","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"strain":{"value":"DC_INS_MPX_0082_L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP693647/2022-08-08"},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-08-08"},"lineage":{"value":"B.1.16"}},"branch_attrs":{"mutations":{"nuc":["A1701-","C1702-","T1703-","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-","T196852-","G196853-","T196854-"]}}},{"name":"NODE_0000046","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.16"}},"branch_attrs":{"mutations":{"nuc":["G23673A","G37974A","-180517A","-180518A","-180519T","-180520G","-180521A","-180522C","-180523G","-180524A","-180525T","-180526A","-180527T","-180528A","-180529C","-180530G","-180531G","-180532A","-180533T","-180534T"],"OPG039":["S149L"],"OPG056":["S354L"]},"labels":{"aa":"OPG039: S149L; OPG056: S354L"}},"children":[{"name":"OP819959","node_attrs":{"div":67,"accession":"OP819959","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"strain":{"value":"SAN_INS_MPX_0971_L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP819959/2022-10-11"},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-10-11"},"lineage":{"value":"B.1.16"}},"branch_attrs":{"mutations":{}}},{"name":"OQ696096","node_attrs":{"div":68,"accession":"OQ696096","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain":{"value":"ANT-LDSP-ANT-MPX-30280C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OQ696096/2022-11-08"},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-11-08"},"lineage":{"value":"B.1.16"}},"branch_attrs":{"mutations":{"nuc":["A164477G","A173314-","T173315-","A173316-","T173317-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG189":["E382G"]},"labels":{"aa":"OPG189: E382G"}}}]}]},{"name":"NODE_0000047","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C132698T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}},"children":[{"name":"NODE_0000048","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T122837G"],"OPG143":["N160T"]},"labels":{"aa":"OPG143: N160T"}},"children":[{"name":"OP555662","node_attrs":{"div":64,"accession":"OP555662","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0595/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555662/2022-09-16"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-16"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T109045C"],"OPG128":["Y4C"]},"labels":{"aa":"OPG128: Y4C"}}},{"name":"OP555606","node_attrs":{"div":63,"accession":"OP555606","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0535/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555606/2022-08-23"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-23"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000049","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C18441T","G22415A","G70002A","G143951A","C148604T","G154188A","T179078-","A179079-","T179080-","A179081-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C196745-","C196746-","A196747-"],"OPG031":["E130K"],"OPG089":["R46K"],"OPG165":["D146N"],"OPG174":["M264I"]},"labels":{"aa":"OPG031: E130K; OPG089: R46K; OPG165: D146N; OPG174: M264I"}},"children":[{"name":"OR499993","node_attrs":{"div":68,"accession":"OR499993","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00537/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR499993/2023-07-06"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-07-06"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C179082-","C179091-","C179100-","C179109-","C179118-","C179127-","C179136-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000050","node_attrs":{"div":69,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C14823A","-179078T","-179079A","-179080T","-179081A","-179083A","-179084T","-179085T","-179086A","-179087T","-179088A","-179089T","-179090A","-179092A","-179093T","-179094T","-179095A","-179096T","-179097A","-179098T","-179099A","-179101A","-179102T","-179103T","-179104A","-179105T","-179106A","-179107T","-179108A","-179110A","-179111T","-179112T","-179113A","-179114T","-179115A","-179116T","-179117A","-179119A","-179120T","-179121T","-179122A","-179123T","-179124A","-179125T","-179126A","-179128A","-179129T","-179130T","-179131A","-179132T","-179133A","-179134T","-179135A","-179137A","-179138T","-179139T","-179140A","-179141T","-179142A","-179143T","-179144A"],"OPG025":["D149Y"]},"labels":{"aa":"OPG025: D149Y"}},"children":[{"name":"OR643702","node_attrs":{"div":69,"accession":"OR643702","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00560/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR643702/2023-08-08"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-08-08"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{}}},{"name":"OR499982","node_attrs":{"div":69,"accession":"OR499982","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00525/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR499982/2023-06-14"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-06-14"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000051","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C170573T"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}},"children":[{"name":"OP415248","node_attrs":{"div":64,"accession":"OP415248","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPX_XJRG9b_9000293"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP415248/2022-08-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G148403A","G148615A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG174":["L261F"]},"labels":{"aa":"OPG174: L261F"}}},{"name":"OP605567","node_attrs":{"div":64,"accession":"OP605567","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain":{"value":"Slovenia-MPXV-25-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Slovenia/OP605567/2022-07-XX"},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C71938T","G73939A","T196886-","T196887-","T196888-"],"OPG092":["R337K"],"OPG094":["D54N"]},"labels":{"aa":"OPG092: R337K; OPG094: D54N"}}},{"name":"OQ451902","node_attrs":{"div":67,"accession":"OQ451902","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI717"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ451902/2022-11-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-11-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-607T","C3602T","C53342T","C124495T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159789A","G190695A","G193608A"],"OPG003":["E336K"],"OPG003_dup":["E336K"],"OPG016":["E96K"],"OPG071":["R366K"]},"labels":{"aa":"OPG003: E336K; OPG003_dup: E336K; OPG016: E96K; OPG071: R366K"}}},{"name":"OR759146","node_attrs":{"div":65,"accession":"OR759146","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain":{"value":"hMpxV/Canada/ON-PHOL053/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OR759146/2022-08-01"},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C3405T","G5375A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G186165A","C191835T","G193805A"],"OPG015":["A261V"],"OPG015_dup":["A261V"],"OPG210":["D1604N"]},"labels":{"aa":"OPG015: A261V; OPG015_dup: A261V; OPG210: D1604N"}}},{"name":"NODE_0000052","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C14098T","C84063T","G111029A","G142493A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G151324A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C187332T"],"OPG163":["D98N"]},"labels":{"aa":"OPG163: D98N"}},"children":[{"name":"OQ503815","node_attrs":{"div":70,"accession":"OQ503815","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00422/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ503815/2022-12-03"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-12-03"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G97749A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G188726A"]}}},{"name":"OR499960","node_attrs":{"div":74,"accession":"OR499960","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00503/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR499960/2023-03-15"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-03-15"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G6746A","C39266T","C63819T","G106927A","G138862A","G169213A"],"OPG083":["V300I"],"OPG125":["T243M"],"OPG156":["S183F"]},"labels":{"aa":"OPG083: V300I; OPG125: T243M; OPG156: S183F"}}}]}]},{"name":"NODE_0000053","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177009A","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG205":["E452K"]},"labels":{"aa":"OPG205: E452K"}},"children":[{"name":"OQ331008","node_attrs":{"div":67,"accession":"OQ331008","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00399/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ331008/2022-12-30"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-12-30"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","T5630C","C21309T","T130733C","G157078A","T179244-","G182535A","A191580G","T196729-","A196730-","T196731-"],"OPG015":["E176G"],"OPG015_dup":["E176G"],"OPG151":["C604R"],"OPG210":["E394K"]},"labels":{"aa":"OPG015: E176G; OPG015_dup: E176G; OPG151: C604R; OPG210: E394K"}}},{"name":"NODE_0000054","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C17048T","G74360A","G93828A","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"],"OPG029":["D8N"],"OPG094":["R194H"],"OPG113":["E700K"]},"labels":{"aa":"OPG029: D8N; OPG094: R194H; OPG113: E700K"}},"children":[{"name":"OQ159028","node_attrs":{"div":66,"accession":"OQ159028","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI633"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ159028/2022-11-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-11-XX"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C41131T"],"OPG060":["E18K"]},"labels":{"aa":"OPG060: E18K"}}},{"name":"OQ735077","node_attrs":{"div":72,"accession":"OQ735077","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"MPXV/PT0626/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OQ735077/2023-03-21"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-03-21"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-609T","A615-","C616-","C10929T","C22179T","G39515A","G77076A","G129659A","C129949T","G139167A","C196638-","T196639-"],"OPG023":["E658K"],"OPG151":["E246K"]},"labels":{"aa":"OPG023: E658K; OPG151: E246K"}}}]},{"name":"NODE_0000055","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C118453T","G137276A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG136":["E379K"],"OPG153":["S131F"]},"labels":{"aa":"OPG136: E379K; OPG153: S131F"}},"children":[{"name":"OR499948","node_attrs":{"div":65,"accession":"OR499948","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00491/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR499948/2023-04-10"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-04-10"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G635-","A636-","A637-","A1697-","G39327A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","T195519-"],"OPG057":["A290V"]},"labels":{"aa":"OPG057: A290V"}}},{"name":"NODE_0000056","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T606-","C117119T","T179078-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-"]}},"children":[{"name":"OR499969","node_attrs":{"div":65,"accession":"OR499969","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00512/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR499969/2023-05-04"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-05-04"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["A179079-","T179080-","A179081-","-179176A","-179177T","-179178A"]}}},{"name":"OR499971","node_attrs":{"div":67,"accession":"OR499971","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00514/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR499971/2023-05-04"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-05-04"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T39397C","T178873C"],"OPG057":["N267D"]},"labels":{"aa":"OPG057: N267D"}}}]}]}]},{"name":"NODE_0000064","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{"nuc":["T606-","G181367A","A196614-"]},"labels":{"clade":"B.1.9"}},"children":[{"name":"ON843175","node_attrs":{"div":62,"accession":"ON843175","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0043/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/ON843175/2022-05-30"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-05-30"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP687938","node_attrs":{"div":65,"accession":"OP687938","author":{"author":"Gigante,C.M.,Acheampong,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Morrison,S.S.,Seabolt,M.H.,Weigand,M.R.,Knipe,K.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,McDermott,D.,Li,Y.","value":"Gigante,C.M.,Acheampong,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Morrison,S.S.,Seabolt,M.H.,Weigand,M.R.,Knipe,K.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,McDermott,D.,Li,Y."},"strain":{"value":"MPXV_USA_2022_NJ0005"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP687938/2022-08-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{"nuc":["G61329A","C101868T","C103427T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG121":["P27S"]},"labels":{"aa":"OPG121: P27S"}}},{"name":"OP693652","node_attrs":{"div":63,"accession":"OP693652","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"strain":{"value":"DC_INS_MPX_0718_L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP693652/2022-08-16"},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-08-16"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{"nuc":["-606T","G134122T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000065","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{"nuc":["G176823A"],"OPG205":["E390K"]},"labels":{"aa":"OPG205: E390K"}},"children":[{"name":"ON880538","node_attrs":{"div":64,"accession":"ON880538","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"strain":{"value":"MpxV/human/CAN/UN-NML-3336/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/ON880538/2022-06-01"},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-01"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{"nuc":["C32627T"]}}},{"name":"ON585038","node_attrs":{"div":64,"accession":"ON585038","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0008/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/ON585038/2022-05-15"},"country":{"value":"Portugal"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"date":{"value":"2022-05-15"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","C16968T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A188351-"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-"}}},{"name":"NODE_0000066","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{"nuc":["C34432T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155157A"],"OPG053":["E87K"],"OPG181":["R249K"]},"labels":{"aa":"OPG053: E87K; OPG181: R249K"}},"children":[{"name":"OP324498","node_attrs":{"div":66,"accession":"OP324498","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0183/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP324498/2022-06-28"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-06-28"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{"nuc":["-606T","-607T","G4195A","C193015T","-196614A","-196615A"],"OPG003":["S138L"],"OPG003_dup":["S138L"]},"labels":{"aa":"OPG003: S138L; OPG003_dup: S138L"}}},{"name":"OP324463","node_attrs":{"div":65,"accession":"OP324463","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0144/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP324463/2022-07-07"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-07"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{}}},{"name":"OP555607","node_attrs":{"div":67,"accession":"OP555607","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0536/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555607/2022-08-22"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-22"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{"nuc":["G13563A","C68792T"],"OPG025":["P569S"]},"labels":{"aa":"OPG025: P569S"}}}]}]}]},{"name":"NODE_0000067","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.17"}},"branch_attrs":{"mutations":{"nuc":["G12169A","G44960A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196789-","A196790-","T196791-"]},"labels":{"clade":"B.1.17"}},"children":[{"name":"OP442552","node_attrs":{"div":63,"accession":"OP442552","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00085/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP442552/2022-07-13"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-07-13"},"lineage":{"value":"B.1.17"}},"branch_attrs":{"mutations":{"nuc":["G771-","T772-","G773-"]}}},{"name":"OP628456","node_attrs":{"div":68,"accession":"OP628456","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-084166/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP628456/2022-07-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.17"}},"branch_attrs":{"mutations":{"nuc":["A11836G","C12850T","G69249A","C113363T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G171959A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196789A","-196790A","-196791T"],"OPG132":["D60N"]},"labels":{"aa":"OPG132: D60N"}}},{"name":"OP580601","node_attrs":{"div":63,"accession":"OP580601","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"hMPX/USA/CA-LACPHL-MA00168/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP580601/2022-09-19"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-09-19"},"lineage":{"value":"B.1.17"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-"]}}},{"name":"OP890576","node_attrs":{"div":67,"accession":"OP890576","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00319/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP890576/2022-11-09"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-11-09"},"lineage":{"value":"B.1.17"}},"branch_attrs":{"mutations":{"nuc":["C39334G","G78034A","C157894T","G178111A"],"OPG057":["A288P"],"OPG099":["D124N"]},"labels":{"aa":"OPG057: A288P; OPG099: D124N"}}},{"name":"NODE_0000068","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.17"}},"branch_attrs":{"mutations":{"nuc":["C177626T"]}},"children":[{"name":"OP442546","node_attrs":{"div":64,"accession":"OP442546","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00070/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP442546/2022-08-19"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-08-19"},"lineage":{"value":"B.1.17"}},"branch_attrs":{"mutations":{"nuc":["C133174T"]}}},{"name":"OQ888843","node_attrs":{"div":66,"accession":"OQ888843","author":{"author":"Hemarajata,P.,Garrigues,J.M.,Green,N.M.","value":"Hemarajata,P.,Garrigues,J.M.,Green,N.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00483/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ888843/2022-10-13"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-10-13"},"lineage":{"value":"B.1.17"}},"branch_attrs":{"mutations":{"nuc":["T39397C","G86148A"],"OPG057":["N267D"]},"labels":{"aa":"OPG057: N267D"}}}]},{"name":"NODE_0000069","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.17"}},"branch_attrs":{"mutations":{"nuc":["A39395-","T39396-","T39397-","C85931T"],"OPG057":["N267-"]},"labels":{"aa":"OPG057: N267-"}},"children":[{"name":"OQ503816","node_attrs":{"div":64,"accession":"OQ503816","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00423/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ503816/2022-12-02"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-12-02"},"lineage":{"value":"B.1.17"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ991943","node_attrs":{"div":66,"accession":"OQ991943","author":{"author":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J.","value":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J."},"strain":{"value":"OQ991943"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ991943/2023-01-13"},"country":{"value":"USA"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2023-01-13"},"lineage":{"value":"B.1.17"}},"branch_attrs":{"mutations":{"nuc":["G71249A","G182189A"],"OPG090":["R24Q"]},"labels":{"aa":"OPG090: R24Q"}}}]}]},{"name":"NODE_0000070","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C141757T","-179172C","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OR126131","node_attrs":{"div":66,"accession":"OR126131","author":{"author":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C.","value":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C."},"strain":{"value":"HRYC_MPXV001"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Spain/OR126131/2022-09-21"},"country":{"value":"Spain"},"institution":{"value":"Hospital Ramon y Cajal, Microbiology"},"date":{"value":"2022-09-21"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C11749-","C34432T","C48324T","G101294A","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","G190695A"],"OPG016":["E96K"],"OPG053":["E87K"],"OPG120":["S152L"]},"labels":{"aa":"OPG016: E96K; OPG053: E87K; OPG120: S152L"}}},{"name":"NODE_0000071","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.18"}},"branch_attrs":{"mutations":{"nuc":["C43706T","T124690C"]},"labels":{"clade":"B.1.18"}},"children":[{"name":"OP628451","node_attrs":{"div":64,"accession":"OP628451","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-083401/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP628451/2022-08-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.18"}},"branch_attrs":{"mutations":{"nuc":["-179173A","-179174T","-179175T","-179176A","-179177T","-179178A"]}}},{"name":"OP748958","node_attrs":{"div":65,"accession":"OP748958","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00272/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP748958/2022-07-18"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-07-18"},"lineage":{"value":"B.1.18"}},"branch_attrs":{"mutations":{"nuc":["G113924A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP890552","node_attrs":{"div":65,"accession":"OP890552","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00294/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP890552/2022-10-06"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-10-06"},"lineage":{"value":"B.1.18"}},"branch_attrs":{"mutations":{"nuc":["T25432G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG040":["Y16S"]},"labels":{"aa":"OPG040: Y16S"}}},{"name":"NODE_0000072","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.18"}},"branch_attrs":{"mutations":{"nuc":["C170049T","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A"]}},"children":[{"name":"OQ320465","node_attrs":{"div":66,"accession":"OQ320465","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_NY0026"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ320465/2022-08-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.18"}},"branch_attrs":{"mutations":{"nuc":["G105147A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OQ503770","node_attrs":{"div":68,"accession":"OQ503770","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-096758/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ503770/2022-09-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.18"}},"branch_attrs":{"mutations":{"nuc":["G902A","T15127-","G87315A","C88489T","G111635A","C196308T"],"OPG001":["S225L"],"OPG001_dup":["S225L"],"OPG109":["R320K"],"OPG130":["P90S"]},"labels":{"aa":"OPG001: S225L; OPG001_dup: S225L; OPG109: R320K; OPG130: P90S"}}},{"name":"NODE_0000073","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.18"}},"branch_attrs":{"mutations":{"nuc":["G67758A"]}},"children":[{"name":"OP837471","node_attrs":{"div":66,"accession":"OP837471","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"strain":{"value":"VAC_INS_MPX_1052_E"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP837471/2022-10-25"},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-10-25"},"lineage":{"value":"B.1.18"}},"branch_attrs":{"mutations":{}}},{"name":"OQ148474","node_attrs":{"div":70,"accession":"OQ148474","author":{"author":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"strain":{"value":"LBMB-UTP_MP-025_VAC"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OQ148474/2022-11-15"},"country":{"value":"Colombia"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"date":{"value":"2022-11-15"},"lineage":{"value":"B.1.18"}},"branch_attrs":{"mutations":{"nuc":["C128242T","G144572A","C166940T","C168829T"],"OPG150":["S155F"],"OPG166":["A59T"]},"labels":{"aa":"OPG150: S155F; OPG166: A59T"}}}]}]}]}]},{"name":"NODE_0000074","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.15"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","G149818A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G151362A"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG176":["D4N"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG176: D4N","clade":"B.1.15"}},"children":[{"name":"ON694335","node_attrs":{"div":63,"accession":"ON694335","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI018"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/ON694335/2022-05-XX"},"country":{"value":"Germany"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.15"}},"branch_attrs":{"mutations":{"nuc":["A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-","A196614-"]}}},{"name":"OP324453","node_attrs":{"div":64,"accession":"OP324453","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0129/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP324453/2022-07-12"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-12"},"lineage":{"value":"B.1.15"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","C18133T","-196615A","-196616T"]}}},{"name":"OP484673","node_attrs":{"div":66,"accession":"OP484673","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI352"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP484673/2022-09-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.15"}},"branch_attrs":{"mutations":{"nuc":["C21128T","G74187T","C151111T"],"OPG037":["E436K"],"OPG094":["Q136H"]},"labels":{"aa":"OPG037: E436K; OPG094: Q136H"}}},{"name":"OP764619","node_attrs":{"div":63,"accession":"OP764619","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI561"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP764619/2022-06-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.15"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000075","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.15"}},"branch_attrs":{"mutations":{"nuc":["C8385T","-11326A","-11327T","-11328C","-11329T","-11330A","-11331C","-11332G","-11333A","-11334T","-11335A","-11336T","-11337T","-11338A","-11339G","-11340A","-11341T","-11342A","-11343C","-11344T","-11345T","-11346C","-11347A","-11348C","-11349T","-11350C","-11351A","-11352A","-11353T","-11354G","-11355A","-11356A","-11357T","-11358C","-11359A","-11360A","-11361T","-11362C","-11363A","-11364C","-11365A","-11366C","-11367A","-11368A","-11369T","-11370C","-11371T","-11372A","-11373A","-11374T","-11375G","-11376T","-11377A","-11378G","-11379G","-11380T","-11381T","-11382T","-11383A","-11384T","-11385G","-11386A","-11387C","-11388A","-11389T","-11390A","-11391A","-11392T","-11393A","-11394G","-11395C","-11396A","-11397T","-11398T","-11399T","-11400T","-11401C","-11402A","-11403G","-11404C","-11405A","-11406G","-11407T","-11408T","-11409C","-11410A","-11411A","-11412T","-11413G","-11414T","-11415T","-11416T","-11417C","-11418T","-11419A","-11420G","-11421A","-11422T","-11423T","-11424C","-11425G","-11426T","-11427T","-11428G","-11429A","-11430T","-11431G","-11432G","-11433C","-11434A","-11435A","-11436T","-11437G","-11438G","-11439T","-11440T","-11441A","-11442T","-11443A","-11444C","-11445A","-11446T","-11447G","-11448T","-11449A","-11450T","-11451A","-11452T","-11453C","-11454C","-11455G","-11456T","-11457T","-11458A","-11459T","-11460T","-11461T","-11462G","-11463A","-11464T","-11465C","-11466T","-11467A","-11468A","-11469T","-11470G","-11471T","-11472T","-11473G","-11474A","-11475C","-11476A","-11477T","-11478C","-11479T","-11480G","-11481A","-11482A","-11483C","-11484C","-11485G","-11486G","-11487A","-11488T","-11489T","-11490C","-11491T","-11492A","-11493G","-11494C","-11495A","-11496G","-11497T","-11498A","-11499A","-11500A","-11501G","-11502A","-11503T","-11504A","-11505C","-11506T","-11507A","-11508G","-11509A","-11510G","-11511A","-11512T","-11513T","-11514G","-11515T","-11516T","-11517T","-11518A","-11519T","-11520T","-11521A","-11522T","-11523A","-11524T","-11525C","-11526T","-11527A","-11528A","-11529C","-11530A","-11531G","-11532C","-11533C","-11534T","-11535T","-11536G","-11537T","-11538G","-11539A","-11540A","-11541G","-11542A","-11543A","-11544G","-11545T","-11546G","-11547T","-11548T","-11549T","-11550C","-11551T","-11552C","-11553C","-11554T","-11555C","-11556G","-11557T","-11558T","-11559T","-11560G","-11561T","-11562C","-11563A","-11564A","-11565T","-11566C","-11567A","-11568T","-11569G","-11570T","-11571T","-11572A","-11573A","-11574T","-11575G","-11576T","-11577C","-11578T","-11579T","-11580T","-11581A","-11582A","-11583G","-11584A","-11585T","-11586A","-11587A","-11588G","-11589G","-11590T","-11591A","-11592G","-11593A","-11594C","-11595A","-11596A","-11597A","-11598T","-11599G","-11600T","-11601T","-11602T","-11603A","-11604T","-11605A","-11606G","-11607T","-11608A","-11609C","-11610T","-11611A","-11612A","-11613G","-11614A","-11615A","-11616T","-11617T","-11618G","-11619G","-11620G","-11621C","-11622A","-11623A","-11624A","-11625C","-11626A","-11627T","-11628A","-11629A","-11630G","-11631A","-11632C","-11633A","-11634T","-11635G","-11636T","-11637C","-11638A","-11639C","-11640A","-11641A","-11642A","-11643G","-11644A","-11645C","-11646C","-11647C","-11648T","-11649T","-11650T","-11651T","-11652T","-11653G","-11654T","-11655A","-11656T","-11657G","-11658T","-11659A","-11660T","-11661A","-11662A","-11663G","-11664T","-11665G","-11666T","-11667A","-11668G","-11669A","-11670A","-11671A","-11672T","-11673T","-11674A","-11675T","-11676A","-11677A","-11678C","-11679A","-11680T","-11681C","-11682C","-11683A","-11684T","-11685A","-11686G","-11687T","-11688T","-11689G","-11690G","-11691A","-11692T","-11693T","-11694C","-11695A","-11696C","-11697A","-11698T","-11699A","-11700G","-11701G","-11702T","-11703G","-11704T","-11705C","-11706C","-11707A","-11708A","-11709T","-11710C","-11711G","-11712G","-11713G","-11714A","-11715T","-11716C","-11717T","-11718C","-11719T","-11720C","-11721C","-11722A","-11723T","-11724C","-11725A","-11726T","-11727C","-11728G","-11729A","-11730G","-11731A","-11732T","-11733G","-11734A","-11735T","-11736T","-11737G","-11738A","-11739C","-11740G","-11741G","-11742C","-11743A","-11744T","-11745C","-11746T","-11747C","-11748C","-11749C","-11750C","-11751C","-11752T","-11753T","-11754C","-11755C","-11756T","-11757T","-11758T","-11759T","-11760T","-11761T","-11762A","-11763G","-11764T","-11765A","-11766G","-11767A","-11768T","-11769A","-11770T","-11771T","-11772T","-11773C","-11774A","-11775T","-11776C","-11777G","-11778T","-11779G","-11780T","-11781A","-11782A","-11783G","-11784A","-11785A","-11786T","-11787C","-11788A","-11789A","-11790T","-11791A","-11792T","-11793T","-11794A","-11795A","-11796T","-11797A","-11798T","-11799T","-11800T","-11801C","-11802T","-11803A","-11804A","-11805A","-11806G","-11807T","-11808A","-11809T","-11810C","-11811T","-11812G","-11813T","-11814G","-11815T","-11816A","-11817T","-11818A","-11819G","-11820C","-11821C","-11822T","-11823C","-11824T","-11825T","-11826T","-11827A","-11828T","-11829T","-11830T","-11831A","-11832C","-11833C","-11834A","-11835C","-11836A","-11837G","-11838C","-11839T","-11840C","-11841C","-11842A","-11843T","-11844A","-11845T","-11846T","-11847C","-11848C","-11849A","-11850A","-11851C","-11852A","-11853T","-11854G","-11855C","-11856A","-11857T","-11858T","-11859C","-11860C","-11861A","-11862C","-11863T","-11864A","-11865G","-11866A","-11867G","-11868G","-11869G","-11870A","-11871T","-11872A","-11873T","-11874C","-11875G","-11876A","-11877T","-11878A","-11879T","-11880C","-11881G","-11882C","-11883C","-11884G","-11885A","-11886A","-11887T","-11888G","-11889T","-11890C","-11891A","-11892T","-11893A","-11894T","-11895A","-11896C","-11897T","-11898C","-11899A","-11900A","-11901T","-11902T","-11903A","-11904G","-11905T","-11906A","-11907T","-11908A","-11909T","-11910G","-11911T","-11912T","-11913G","-11914G","-11915A","-11916G","-11917G","-11918A","-11919C","-11920A","-11921T","-11922C","-11923C","-11924G","-11925A","-11926G","-11927T","-11928T","-11929C","-11930A","-11931T","-11932T","-11933G","-11934T","-11935T","-11936T","-11937T","-11938C","-11939A","-11940A","-11941T","-11942A","-11943T","-11944C","-11945A","-11946A","-11947A","-11948G","-11949A","-11950G","-11951A","-11952T","-11953G","-11954G","-11955T","-11956T","-11957T","-11958C","-11959C","-11960T","-11961T","-11962A","-11963T","-11964C","-11965A","-11966T","-11967T","-11968T","-11969C","-11970T","-11971C","-11972C","-11973A","-11974T","-11975A","-11976G","-11977T","-11978G","-11979G","-11980T","-11981A","-11982C","-11983A","-11984A","-11985T","-11986A","-11987C","-11988T","-11989A","-11990C","-11991A","-11992C","-11993A","-11994T","-11995T","-11996A","-11997T","-11998T","-11999C","-12000C","-12001G","-12002T","-12003A","-12004C","-12005G","-12006G","-12007C","-12008T","-12009T","-12010T","-12011C","-12012C","-12013A","-12014T","-12015T","-12016C","-12017T","-12018C","-12019C","-12020A","-12021A","-12022A","-12023A","-12024A","-12025C","-12026A","-12027A","-12028T","-12029T","-12030T","-12031T","-12032A","-12033C","-12034C","-12035A","-12036A","-12037A","-12038T","-12039C","-12040T","-12041A","-12042A","-12043A","-12044T","-12045C","-12046T","-12047A","-12048C","-12049A","-12050T","-12051C","-12052T","-12053T","-12054T","-12055A","-12056T","-12057T","-12058G","-12059T","-12060A","-12061T","-12062C","-12063T","-12064A","-12065T","-12066A","-12067A","-12068T","-12069C","-12070A","-12071C","-12072T","-12073A","-12074T","-12075T","-12076T","-12077A","-12078G","-12079A","-12080T","-12081A","-12082A","-12083T","-12084C","-12085A","-12086G","-12087C","-12088C","-12089A","-12090T","-12091A","-12092A","-12093T","-12094T","-12095C","-12096C","-12097T","-12098C","-12099G","-12100A","-12101G","-12102T","-12103G","-12104C","-12105A","-12106A","-12107C","-12108A","-12109T","-12110G","-12111T","-12112T","-12113A","-12114G","-12115A","-12116T","-12117C","-12118G","-12119T","-12120C","-12121T","-12122A","-12123T","-12124A","-12125T","-12126A","-12127T","-12128G","-12129A","-12130A","-12131T","-12132A","-12133A","-12134G","-12135C","-12136C","-12137G","-12138T","-12139G","-12140T","-12141T","-12142A","-12143T","-12144C","-12145T","-12146A","-12147T","-12148T","-12149C","-12150C","-12151T","-12152T","-12153T","-12154C","-12155A","-12156T","-12157T","-12158A","-12159A","-12160C","-12161A","-12162A","-12163T","-12164T","-12165T","-12166A","-12167A","-12168C","-12169G","-12170A","-12171T","-12172G","-12173T","-12174C","-12175T","-12176A","-12177T","-12178A","-12179T","-12180C","-12181T","-12182A","-12183T","-12184A","-12185T","-12186G","-12187A","-12188G","-12189A","-12190T","-12191G","-12192A","-12193C","-12194T","-12195T","-12196A","-12197A","-12198T","-12199A","-12200T","-12201A","-12202A","-12203T","-12204A","-12205T","-12206T","-12207G","-12208A","-12209A","-12210G","-12211A","-12212G","-12213C","-12214T","-12215G","-12216T","-12217A","-12218C","-12219A","-12220A","-12221T","-12222A","-12223G","-12224T","-12225T","-12226T","-12227T","-12228T","-12229A","-12230T","-12231C","-12232T","-12233A","-12234T","-12235A","-12236G","-12237A","-12238A","G40242A","C40335T","C127609T","G139582A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG023":["-222S","-223I","-224D","-225K","-226N","-227Y","-228C","-229T","-230A","-231L","-232Q","-233Y","-234Y","-235I","-236K","-237S","-238S","-239H","-240I","-241D","-242I","-243D","-244I","-245V","-246K","-247L","-248L","-249M","-250K","-251G","-252I","-253D","-254N","-255T","-256A","-257Y","-258S","-259Y","-260I","-261D","-262D","-263L","-264T","-265C","-266C","-267T","-268R","-269G","-270I","-271M","-272A","-273D","-274Y","-275L","-276N","-277S","-278D","-279Y","-280R","-281Y","-282N","-283K","-284D","-285V","-286D","-287L","-288D","-289L","-290V","-291K","-292L","-293F","-294L","-295E","-296N","-297G","-298K","-299P","-300Y","-301G","-302I","-303M","-304C","-305S","-306I","-307V","-308P","-309L","-310W","-311R","-312N","-313D","-314K","-315E","-316T","-317I","-318S","-319L","-320I","-321L","-322K","-323T","-324M","-325N","-326S","-327D","-328V","-329L","-330Q","-331H","-332I","-333L","-334I","-335E","-336Y","-337M","-338T","-339F","-340G","-341D","-342I","-343D","-344I","-345P","-346L","-347V","-348E","-349C","-350M","-351L","-352E","-353Y","-354G","-355A","-356V","-357V","-358N","-359K","-360E","-361A","-362I","-363H","-364R","-365Y","-366F","-367R","-368N","-369I","-370N","-371I","-372D","-373S","-374Y","-375T","-376M","-377K","-378Y","-379L","-380L","-381K","-382K","-383E","-384G","-385G","-386D","-387A","-388V","-389N","-390H","-391L","-392D","-393D","-394G","-395E","-396I","-397P","-398I","-399G","-400H","-401L","-402C","-403E","-404S","-405N","-406Y","-407G","-408C","-409Y","-410N","-411F","-412Y","-413T","-414Y","-415T","-416Y","-417K","-418K","-419G","-420L","-421C","-422D","-423M","-424S","-425Y","-426V","-427C","-428P","-429I","-430L","-431S","-432T","-433I","-434N","-435I","-436C","-437L","-438P","-439Y","-440L","-441K","-442D","-443I","-444N","-445M","-446I","-447D","-448K","-449R","-450G","-451E","-452T","-453L","-454L","-455H","-456K","-457A","-458V","-459R","-460Y","-461N","-462K","-463Q","-464S","-465L","-466V","-467S","-468L","-469L","-470L","-471E","-472S","-473G","-474S","-475D","-476V","-477N","-478I","-479R","-480S","-481N","-482N","-483G","-484Y","-485T","-486C","-487I","-488T","-489I","-490A","-491I","-492N","-493E","-494S","-495R","-496N","-497I","-498E","-499L","-500L","-501K","-502M","-503L","-504L","-505C","-506H","-507K","-508P","-509T","-510L","-511D","-512C","-513V","-514I","-515D","-516S","-517L","-518S","-519E","-520V","-521S","-522N","-523I","-524V","-525D"],"OPG058":["E34K"]},"labels":{"aa":"OPG023: -222S, -223I, -224D, -225K, -226N, -227Y, -228C, -229T, -230A, -231L, -232Q, -233Y, -234Y, -235I, -236K, -237S, -238S, -239H, -240I, -241D, -242I, -243D, -244I, -245V, -246K, -247L, -248L, -249M, -250K, -251G, -252I, -253D, -254N, -255T, -256A, -257Y, -258S, -259Y, -260I, -261D, -262D, -263L, -264T, -265C, -266C, -267T, -268R, -269G, -270I, -271M, -272A, -273D, -274Y, -275L, -276N, -277S, -278D, -279Y, -280R, -281Y, -282N, -283K, -284D, -285V, -286D, -287L, -288D, -289L, -290V, -291K, -292L, -293F, -294L, -295E, -296N, -297G, -298K, -299P, -300Y, -301G, -302I, -303M, -304C, -305S, -306I, -307V, -308P, -309L, -310W, -311R, -312N, -313D, -314K, -315E, -316T, -317I, -318S, -319L, -320I, -321L, -322K, -323T, -324M, -325N, -326S, -327D, -328V, -329L, -330Q, -331H, -332I, -333L, -334I, -335E, -336Y, -337M, -338T, -339F, -340G, -341D, -342I, -343D, -344I, -345P, -346L, -347V, -348E, -349C, -350M, -351L, -352E, -353Y, -354G, -355A, -356V, -357V, -358N, -359K, -360E, -361A, -362I, -363H, -364R, -365Y, -366F, -367R, -368N, -369I, -370N, -371I, -372D, -373S, -374Y, -375T, -376M, -377K, -378Y, -379L, -380L, -381K, -382K, -383E, -384G, -385G, -386D, -387A, -388V, -389N, -390H, -391L, -392D, -393D, -394G, -395E, -396I, -397P, -398I, -399G, -400H, -401L, -402C, -403E, -404S, -405N, -406Y, -407G, -408C, -409Y, -410N, -411F, -412Y, -413T, -414Y, -415T, -416Y, -417K, -418K, -419G, -420L, -421C, -422D, -423M, -424S, -425Y, -426V, -427C, -428P, -429I, -430L, -431S, -432T, -433I, -434N, -435I, -436C, -437L, -438P, -439Y, -440L, -441K, -442D, -443I, -444N, -445M, -446I, -447D, -448K, -449R, -450G, -451E, -452T, -453L, -454L, -455H, -456K, -457A, -458V, -459R, -460Y, -461N, -462K, -463Q, -464S, -465L, -466V, -467S, -468L, -469L, -470L, -471E, -472S, -473G, -474S, -475D, -476V, -477N, -478I, -479R, -480S, -481N, -482N, -483G, -484Y, -485T, -486C, -487I, -488T, -489I, -490A, -491I, -492N, -493E, -494S, -495R, -496N, -497I, -498E, -499L, -500L, -501K, -502M, -503L, -504L, -505C, -506H, -507K, -508P, -509T, -510L, -511D, -512C, -513V, -514I, -515D, -516S, -517L, -518S, -519E, -520V, -521S, -522N, -523I, -524V, -525D; OPG058: E34K"}},"children":[{"name":"OP819950","node_attrs":{"div":70,"accession":"OP819950","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"strain":{"value":"MET_INS_MPX_0956_C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP819950/2022-10-12"},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-10-12"},"lineage":{"value":"B.1.15"}},"branch_attrs":{"mutations":{"nuc":["G144284A","C171808T","G196973-","A196974-","A196975-"],"OPG165":["D257N"],"OPG199":["S274L"]},"labels":{"aa":"OPG165: D257N; OPG199: S274L"}}},{"name":"OR086972","node_attrs":{"div":73,"accession":"OR086972","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_163/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR086972/2022-07-27"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-27"},"lineage":{"value":"B.1.15"}},"branch_attrs":{"mutations":{"nuc":["G31180A","C142626T","G158549A","G159341A","C170750T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG163":["S142L"],"OPG185":["G142E"],"OPG198":["A238V"]},"labels":{"aa":"OPG163: S142L; OPG185: G142E; OPG198: A238V"}}},{"name":"NODE_0000076","node_attrs":{"div":69,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.15"}},"branch_attrs":{"mutations":{"nuc":["C21324T"]}},"children":[{"name":"OP837479","node_attrs":{"div":72,"accession":"OP837479","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"strain":{"value":"DC_INS_MPX_1024_L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP837479/2022-09-20"},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-09-20"},"lineage":{"value":"B.1.15"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","G68296A","C144166T","C181495T"],"OPG085":["S79L"],"OPG210":["S47L"]},"labels":{"aa":"OPG085: S79L; OPG210: S47L"}}},{"name":"NODE_0000077","node_attrs":{"div":70,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.15"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G180556A"]}},"children":[{"name":"OP623592","node_attrs":{"div":72,"accession":"OP623592","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"strain":{"value":"BOL-UNIMOL-MPX-293165-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP623592/2022-08-09"},"country":{"value":"Colombia"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"date":{"value":"2022-08-09"},"lineage":{"value":"B.1.15"}},"branch_attrs":{"mutations":{"nuc":["C18213T","G141921A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG031":["E206K"]},"labels":{"aa":"OPG031: E206K"}}},{"name":"OR035721","node_attrs":{"div":70,"accession":"OR035721","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_115"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR035721/2022-10-28"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1.15"}},"branch_attrs":{"mutations":{"nuc":["T196712-","A196713-","T196714-"]}}}]}]}]}]},{"name":"NODE_0000078","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.6"}},"branch_attrs":{"mutations":{"nuc":["G111029A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]},"labels":{"clade":"B.1.6"}},"children":[{"name":"OP320552","node_attrs":{"div":63,"accession":"OP320552","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"strain":{"value":"LIM-INS-012"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Peru/OP320552/2022-07-06"},"country":{"value":"Peru"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"date":{"value":"2022-07-06"},"lineage":{"value":"B.1.6"}},"branch_attrs":{"mutations":{"nuc":["C96110T"],"OPG117":["S21L"]},"labels":{"aa":"OPG117: S21L"}}},{"name":"OP289783","node_attrs":{"div":62,"accession":"OP289783","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Mestanza,O.,Lope,P.,Nunez,A.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Mestanza,O.,Lope,P.,Nunez,A."},"strain":{"value":"LIM-INS-003"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Peru/OP289783/2022-06-27"},"country":{"value":"Peru"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"date":{"value":"2022-06-27"},"lineage":{"value":"B.1.6"}},"branch_attrs":{"mutations":{}}},{"name":"OP289782","node_attrs":{"div":62,"accession":"OP289782","author":{"author":"Silva,I.,Jimenez,V.,Hurtado,V.,Barcena,L.","value":"Silva,I.,Jimenez,V.,Hurtado,V.,Barcena,L."},"strain":{"value":"LIM-INS-001"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Peru/OP289782/2022-06-25"},"country":{"value":"Peru"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"date":{"value":"2022-06-25"},"lineage":{"value":"B.1.6"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-196615A","-196616A","-196617A"]}}},{"name":"OP431402","node_attrs":{"div":63,"accession":"OP431402","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain":{"value":"ANT-LDSP-ANT-MPX-22752-O"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP431402/2022-08-18"},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-08-18"},"lineage":{"value":"B.1.6"}},"branch_attrs":{"mutations":{"nuc":["G15814A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP536765","node_attrs":{"div":64,"accession":"OP536765","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"9000387"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP536765/2022-08-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.6"}},"branch_attrs":{"mutations":{"nuc":["G59112A","C87978T"]}}},{"name":"OQ197863","node_attrs":{"div":63,"accession":"OQ197863","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Rosales,A.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Rosales,A.,Mercado-Reyes,M.M."},"strain":{"value":"DC_INS_MPX-1122-H"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OQ197863/2022-10-22"},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-10-22"},"lineage":{"value":"B.1.6"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C151204T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"]}}},{"name":"OQ348868","node_attrs":{"div":64,"accession":"OQ348868","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000120/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ348868/2022-09-20"},"country":{"value":"USA"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2022-09-20"},"lineage":{"value":"B.1.6"}},"branch_attrs":{"mutations":{"nuc":["-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","G150364A","C166930T"],"OPG176":["E186K"],"OPG192":["S67L"]},"labels":{"aa":"OPG176: E186K; OPG192: S67L"}}},{"name":"OQ503831","node_attrs":{"div":66,"accession":"OQ503831","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00408/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ503831/2023-01-11"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-01-11"},"lineage":{"value":"B.1.6"}},"branch_attrs":{"mutations":{"nuc":["T606-","G10945A","G39515A","C44627T","G56276A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A196614-"],"OPG064":["M424I"]},"labels":{"aa":"OPG064: M424I"}}},{"name":"NODE_0000079","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.6"}},"branch_attrs":{"mutations":{"nuc":["G132863A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A181356-","T181357-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","A181366-","A181368-","A181369-","A181370-","T181371-","T181372-"]}},"children":[{"name":"OP642401","node_attrs":{"div":63,"accession":"OP642401","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain":{"value":"ANT-LDSP-ANT-MPX-24947E"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"strain_display":{"value":"Colombia/OP642401/2022-09-12"},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-09-12"},"lineage":{"value":"B.1.6"}},"branch_attrs":{"mutations":{"nuc":["C181355-","G181358-","C181365-","G181367-"]}}},{"name":"OQ696099","node_attrs":{"div":66,"accession":"OQ696099","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain":{"value":"ANT-LDSP-ANT-MPX-30518C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OQ696099/2022-11-09"},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-11-09"},"lineage":{"value":"B.1.6"}},"branch_attrs":{"mutations":{"nuc":["G63811A","G167862A","C170130T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","-181356A","-181357T","-181359A","-181360A","-181361T","-181362T","-181363T","-181364T","-181366A","-181368A","-181369A","-181370A","-181371T","-181372T"],"OPG193":["D177N"]},"labels":{"aa":"OPG193: D177N"}}}]}]},{"name":"NODE_0000080","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["G175093A","-179194A","-179195T"],"OPG204":["D188N"]},"labels":{"aa":"OPG204: D188N","clade":"B.1.13"}},"children":[{"name":"OP536663","node_attrs":{"div":64,"accession":"OP536663","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"strain":{"value":"MPXV-USA-IL-IDPH-002"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP536663/2022-08-04"},"country":{"value":"USA"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"date":{"value":"2022-08-04"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G119424A","G125452A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG136":["S55L"],"OPG146":["S63L"]},"labels":{"aa":"OPG136: S55L; OPG146: S63L"}}},{"name":"NODE_0000081","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["G22814A","G55162A","C118921T","G137128A","G167910A","A173316-","T173317-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG038":["H116Y"],"OPG074":["S655L"],"OPG136":["D223N"],"OPG193":["E193K"]},"labels":{"aa":"OPG038: H116Y; OPG074: S655L; OPG136: D223N; OPG193: E193K"}},"children":[{"name":"OQ320456","node_attrs":{"div":67,"accession":"OQ320456","author":{"author":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y.","value":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_KS0004"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ320456/2022-10-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T"]}}},{"name":"OQ721921","node_attrs":{"div":68,"accession":"OQ721921","author":{"author":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y.","value":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_KS0005"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ721921/2022-09-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["C110297T","A173314-","T173315-"]}}}]},{"name":"NODE_0000082","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["C132520T"]}},"children":[{"name":"OP257254","node_attrs":{"div":63,"accession":"OP257254","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/OH-UW-073812/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP257254/2022-08-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000083","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["G99832A"],"OPG118":["D463N"]},"labels":{"aa":"OPG118: D463N"}},"children":[{"name":"OP310050","node_attrs":{"div":65,"accession":"OP310050","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/OH-UW-085701/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP310050/2022-08-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["C16327T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR160418","node_attrs":{"div":70,"accession":"OR160418","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-052-0034/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR160418/2023-05-10"},"country":{"value":"USA"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-05-10"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["C27520T","G58883A","G102186A","G129583A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G171410A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A179194-","T179195-","C182950T"],"OPG043":["A146T"],"OPG121":["E133K"],"OPG210":["S532L"]},"labels":{"aa":"OPG043: A146T; OPG121: E133K; OPG210: S532L"}}}]},{"name":"NODE_0000084","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["G165086A","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A179194-","T179195-"]}},"children":[{"name":"OP303783","node_attrs":{"div":67,"accession":"OP303783","author":{"author":"Gigante,C.M.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.M.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_IL0028"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP303783/2022-06-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["C55966T","C85055T","C173668T"],"OPG074":["R387K"]},"labels":{"aa":"OPG074: R387K"}}},{"name":"OP597781","node_attrs":{"div":65,"accession":"OP597781","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"strain":{"value":"MN-MDH-MPXV_0007"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP597781/2022-07-05"},"country":{"value":"USA"},"institution":{"value":"Minnesota Department of Health"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["G127678A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-"],"OPG149":["M161I"]},"labels":{"aa":"OPG149: M161I"}}}]},{"name":"NODE_0000085","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["C21383T","G85431A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG037":["G351S"],"OPG106":["S23F"]},"labels":{"aa":"OPG037: G351S; OPG106: S23F"}},"children":[{"name":"OP270476","node_attrs":{"div":66,"accession":"OP270476","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Friesen,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Friesen,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI287"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP270476/2022-08-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["C172851T","A179194-","T179195-"]}}},{"name":"OQ773520","node_attrs":{"div":67,"accession":"OQ773520","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI901"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ773520/2022-07-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["C146446T","C147140T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG170":["M111I"]},"labels":{"aa":"OPG170: M111I"}}}]}]}]},{"name":"NODE_0000091","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C148268T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}},"children":[{"name":"OR264450","node_attrs":{"div":65,"accession":"OR264450","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain":{"value":"65_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Australia/OR264450/2022-08-25"},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-25"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T76084-","T76085-","T96531G","G158414A","G159694A"],"OPG185":["V260I"]},"labels":{"aa":"OPG185: V260I"}}},{"name":"NODE_0000092","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["G9963A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG021":["R126K"]},"labels":{"aa":"OPG021: R126K","clade":"B.1.19"}},"children":[{"name":"OP270026","node_attrs":{"div":63,"accession":"OP270026","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"strain":{"value":"MpxV/human/CAN/UN-NML-4017/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OP270026/2022-07-05"},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-196615A","-196616A","-196617A"]}}},{"name":"OP838893","node_attrs":{"div":63,"accession":"OP838893","author":{"author":"Viscardi,M.,Cozzolino,L.,De Martinis,C.,Cardillo,L.,Fusco,G.","value":"Viscardi,M.,Cozzolino,L.,De Martinis,C.,Cardillo,L.,Fusco,G."},"strain":{"value":"ID6821"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Italy/OP838893/2022-06-21"},"country":{"value":"Italy"},"institution":{"value":"Istituto Zooprofilattico Sperimentale del Mezzogiorno, Hanimal Health"},"date":{"value":"2022-06-21"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","T133100-","T133101-","T133102-","C133103-","G133104-","A133105-","A133106-","T133107-","T133108-","C133109-","A133110-","C133111-","G133112-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A157678-","A157679-","A157680-","A157681-","T157682-","T157683-","T157684-","T157685-","A157686-","A157687-","G157688-","C157689-","G157690-","A157691-","T157692-","G157693-","A157694-","T157695-","A157696-","T163214-","C163215-","T163216-","T163217-","A163218-","T163219-","A163220-","T163221-","A163417-","A163418-","T163419-","T163420-","C163421-","T163422-","T163423-","C163424-","C163425-","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","G174537-","A174538-","T174539-","G174540-","A174541-","A174542-","A180482-","T180483-","T180484-","A180485-","A180486-","A180487-","A180488-","A180489-","A181114-","T181115-","T181116-","C181117-","C181118-","T181119-","T181120-","A181121-","T181122-","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-"],"OPG159":["N124-","Y125-","N126-"],"OPG189":["N29-","S30-","S31-"]},"labels":{"aa":"OPG159: N124-, Y125-, N126-; OPG189: N29-, S30-, S31-"}}},{"name":"OR035726","node_attrs":{"div":65,"accession":"OR035726","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_120"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR035726/2022-10-28"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["C22739T","G133104A","G133231A","T137560-","G164487A"],"OPG038":["E141K"]},"labels":{"aa":"OPG038: E141K"}}},{"name":"NODE_0000093","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["G77415A","T133101-","T133102-"]}},"children":[{"name":"OR095050","node_attrs":{"div":67,"accession":"OR095050","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_232/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR095050/2022-08-12"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-12"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["G57033A","G83609A","G150003A","C196750-","T196751-","A196752-"]}}},{"name":"OR086965","node_attrs":{"div":68,"accession":"OR086965","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_156/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR086965/2022-07-27"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-27"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["C71016T","G133319A","C176069T","G181309A"],"OPG089":["S384L"]},"labels":{"aa":"OPG089: S384L"}}}]},{"name":"NODE_0000094","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["G150003A","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"]}},"children":[{"name":"OP382486","node_attrs":{"div":67,"accession":"OP382486","author":{"author":"Colson,P.","value":"Colson,P."},"strain":{"value":"hMPXV-IHU00009"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"France/OP382486/2022-07-07"},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-07"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["C38483T","C164272T","G175971A"],"OPG189":["R314C"],"OPG205":["E106K"]},"labels":{"aa":"OPG189: R314C; OPG205: E106K"}}},{"name":"OQ172215","node_attrs":{"div":68,"accession":"OQ172215","author":{"author":"Zeggagh,J.,Ferraris,O.,Salmona,M.,Tarantola,A.,Molina,J.M.,Delaugerre,C.","value":"Zeggagh,J.,Ferraris,O.,Salmona,M.,Tarantola,A.,Molina,J.M.,Delaugerre,C."},"strain":{"value":"MPXV-1047"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"France/OQ172215/2022-06-07"},"country":{"value":"France"},"institution":{"value":"Hopital Saint Louis, Paris"},"date":{"value":"2022-06-07"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["A2591G","A31053G","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133171-","C133172-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T133639-","A150635-","A152676-","T152686-","T155897A","C173533A","A179077T","A179079T","A179081T","C179082T","A179083T","A179086T","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","T194619C","T194627G"],"OPG002":["F54S"],"OPG002_dup":["F54S","C57G"],"OPG047":["C48R"]},"labels":{"aa":"OPG002: F54S; OPG002_dup: F54S, C57G; OPG047: C48R"}}},{"name":"OQ427121","node_attrs":{"div":65,"accession":"OQ427121","author":{"author":"Gigante,C.,Cogswell,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Grenz,L.,Li,Y.","value":"Gigante,C.,Cogswell,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Grenz,L.,Li,Y."},"strain":{"value":"MPXV_USA_2022_OR0008"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ427121/2022-06-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["-607T","C150140T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"],"OPG176":["S111L"]},"labels":{"aa":"OPG176: S111L"}}},{"name":"NODE_0000095","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["A169944T","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C185326T","-196615A"],"OPG197":["E92V"],"OPG210":["S1324L"]},"labels":{"aa":"OPG197: E92V; OPG210: S1324L"}},"children":[{"name":"OP555643","node_attrs":{"div":67,"accession":"OP555643","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0572/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555643/2022-09-05"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-05"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["-607T","C55057T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-"],"OPG073":["E29K"]},"labels":{"aa":"OPG073: E29K"}}},{"name":"OQ159056","node_attrs":{"div":70,"accession":"OQ159056","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI661"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ159056/2022-09-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["C2652T","G9584A","C87741T","G98995A","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG002":["D34N"],"OPG118":["E184K"]},"labels":{"aa":"OPG002: D34N; OPG118: E184K"}}}]},{"name":"NODE_0000096","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["C74417T"],"OPG094":["S213L"]},"labels":{"aa":"OPG094: S213L"}},"children":[{"name":"OP205108","node_attrs":{"div":65,"accession":"OP205108","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPXV_UK_2022_9000145"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP205108/2022-06-16"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-16"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{}}},{"name":"OP413717","node_attrs":{"div":65,"accession":"OP413717","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"9000353"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP413717/2022-08-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{}}},{"name":"OP555533","node_attrs":{"div":66,"accession":"OP555533","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0452/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555533/2022-08-04"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-04"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["-607T","-609T","G610-","T611-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C177833T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP536803","node_attrs":{"div":66,"accession":"OP536803","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"9000431"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP536803/2022-09-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["T606-","C22179T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G190782-","A190783-","A190784-","A190785-","A196614-"],"OPG016":["E125-","I126-"]},"labels":{"aa":"OPG016: E125-, I126-"}}}]}]}]}]},{"name":"NODE_0000097","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-607T","G53326A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-196615A"]}},"children":[{"name":"OR264430","node_attrs":{"div":64,"accession":"OR264430","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain":{"value":"51_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Australia/OR264430/2022-09-05"},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-09-05"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C15582T","C121104T","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG138":["R10K"]},"labels":{"aa":"OPG138: R10K"}}},{"name":"NODE_0000098","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["T133102-","C164385T","C187620T"]},"labels":{"clade":"B.1.20"}},"children":[{"name":"OQ320441","node_attrs":{"div":64,"accession":"OQ320441","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"strain":{"value":"MPXV_USA_2022_TX0040"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ320441/2022-10-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"]}}},{"name":"OQ427127","node_attrs":{"div":65,"accession":"OQ427127","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"strain":{"value":"MPXV_USA_2022_TX0046"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ427127/2022-10-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["G98456A","-133102T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-"],"OPG118":["G4E"]},"labels":{"aa":"OPG118: G4E"}}},{"name":"OQ721939","node_attrs":{"div":66,"accession":"OQ721939","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_TN0016"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ721939/2022-09-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["C76839T","G89916A","T133101-"],"OPG097":["D13N"]},"labels":{"aa":"OPG097: D13N"}}},{"name":"NODE_0000099","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["T602-","T603-","T604-","T605-","T606-","T607-","-133102T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177398A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","A196610-","A196611-","A196612-","A196613-","A196614-","A196615-"]}},"children":[{"name":"OQ427126","node_attrs":{"div":67,"accession":"OQ427126","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"strain":{"value":"MPXV_USA_2022_TX0045"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ427126/2022-11-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-11-XX"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["G36027A","C72221T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A"],"OPG055":["R353C"],"OPG092":["E243K"]},"labels":{"aa":"OPG055: R353C; OPG092: E243K"}}},{"name":"OQ918695","node_attrs":{"div":65,"accession":"OQ918695","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00484/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ918695/2023-02-07"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-02-07"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ644783","node_attrs":{"div":65,"accession":"OQ644783","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00477/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ644783/2023-01-17"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-01-17"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["T179179-","A179180-"]}}},{"name":"OR464208","node_attrs":{"div":67,"accession":"OR464208","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"strain":{"value":"MPXV_USA_2022_TX0055"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR464208/2022-12-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-12-XX"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["G129761A","G150577-","A150578-","T150579-","A150580-","T150581-","G150582-","A150583-","T150584-","G150585-","T165597C","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG151":["D280N"],"OPG190":["V159A"]},"labels":{"aa":"OPG151: D280N; OPG190: V159A"}}},{"name":"NODE_0000100","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["C177899T","T179179-","A179180-"]}},"children":[{"name":"OR665164","node_attrs":{"div":70,"accession":"OR665164","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-098659/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR665164/2023-09-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-09-XX"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["-602T","G141131A","G146690A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C159608T","G163900-","A163901-","A163902-","T163903-","C163904-","A163905-","G168964A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A192393C","G192396A","A192402G","-196610A"],"OPG170":["S30F"],"OPG185":["S231F"],"OPG189":["E190-","S191-"]},"labels":{"aa":"OPG170: S30F; OPG185: S231F; OPG189: E190-, S191-"}}},{"name":"OR499972","node_attrs":{"div":68,"accession":"OR499972","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00515/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR499972/2023-04-25"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-04-25"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["G18919A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G187517A"]}}},{"name":"OR499966","node_attrs":{"div":67,"accession":"OR499966","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00509/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR499966/2023-03-31"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-03-31"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["G115293A"],"OPG133":["A135V"]},"labels":{"aa":"OPG133: A135V"}}},{"name":"NODE_0000101","node_attrs":{"div":71,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["C15718T","C22349T","C83753T","G98119A","C113363T"],"OPG037":["E29K"],"OPG117":["E691K"],"OPG132":["D60N"]},"labels":{"aa":"OPG037: E29K; OPG117: E691K; OPG132: D60N"}},"children":[{"name":"OR643703","node_attrs":{"div":74,"accession":"OR643703","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00561/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR643703/2023-08-09"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-08-09"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["C11710T","G41336A","G155611A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR499987","node_attrs":{"div":71,"accession":"OR499987","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00531/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR499987/2023-06-30"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-06-30"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000102","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["C20453T","T164946C"]}},"children":[{"name":"OR449306","node_attrs":{"div":68,"accession":"OR449306","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2023/RKI1020"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OR449306/2023-07-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2023-07-XX"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["-602T","-603T","-604T","-605T","-606T","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"]}}},{"name":"OR421479","node_attrs":{"div":68,"accession":"OR421479","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0022/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR421479/2023-05-04"},"country":{"value":"USA"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-05-04"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{}}},{"name":"OR502627","node_attrs":{"div":71,"accession":"OR502627","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0094/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR502627/2023-07-26"},"country":{"value":"USA"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-07-26"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","C43803T","C105798T","C180618T","A196723-","G196724-","A196725-"],"OPG064":["G699E"],"OPG209":["S34L"]},"labels":{"aa":"OPG064: G699E; OPG209: S34L"}}}]}]}]}]}]},{"name":"NODE_0000103","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["C18133T","G67611A","G130231A","G159277A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG185":["E121K"]},"labels":{"aa":"OPG185: E121K","clade":"B.1.11"}},"children":[{"name":"OP169336","node_attrs":{"div":65,"accession":"OP169336","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-070499/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP169336/2022-07-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A"]}}},{"name":"OP123055","node_attrs":{"div":66,"accession":"OP123055","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A."},"strain":{"value":"MpxV/human/USA/OH-UW-070822/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP123055/2022-07-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","G121374A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A","-196616A"]}}},{"name":"OP257250","node_attrs":{"div":68,"accession":"OP257250","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-087527/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP257250/2022-08-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["-607T","G2590A","C66878T","G148419A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C194620T","-196615A"],"OPG085":["D552N"],"OPG174":["S326F"]},"labels":{"aa":"OPG085: D552N; OPG174: S326F"}}},{"name":"OP390178","node_attrs":{"div":65,"accession":"OP390178","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"strain":{"value":"MAG-UNIMOL-MPX-292982-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP390178/2022-08-20"},"country":{"value":"Colombia"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"date":{"value":"2022-08-20"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP378706","node_attrs":{"div":66,"accession":"OP378706","author":{"author":"Gigante,C.M.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.M.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_IL0053"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP378706/2022-06-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["C161002T","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP555545","node_attrs":{"div":65,"accession":"OP555545","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0466/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555545/2022-08-05"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-05"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP524006","node_attrs":{"div":66,"accession":"OP524006","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI404"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP524006/2022-09-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G182634A","-196615A"],"OPG210":["D427N"]},"labels":{"aa":"OPG210: D427N"}}},{"name":"OP693656","node_attrs":{"div":67,"accession":"OP693656","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"strain":{"value":"CUN_INS_MPX_0751_C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP693656/2022-09-10"},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-09-10"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["C33832T","C42036T"],"OPG052":["R55Q"]},"labels":{"aa":"OPG052: R55Q"}}},{"name":"OQ261700","node_attrs":{"div":65,"accession":"OQ261700","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain":{"value":"ANT-LDSP-ANT-MPX-28220C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OQ261700/2022-10-13"},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-10-13"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{}}},{"name":"OP920682","node_attrs":{"div":67,"accession":"OP920682","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00344/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP920682/2022-11-09"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-11-09"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["-607T","G39327A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177273A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"],"OPG057":["A290V"],"OPG205":["D540N"]},"labels":{"aa":"OPG057: A290V; OPG205: D540N"}}},{"name":"OP890530","node_attrs":{"div":67,"accession":"OP890530","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00296/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP890530/2022-10-04"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-10-04"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G154531A","C174287T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OR035719","node_attrs":{"div":68,"accession":"OR035719","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_113"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR035719/2022-10-28"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["T133102-","C142797T","C167995T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G189258A"],"OPG164":["S7L"],"OPG193":["S221F"]},"labels":{"aa":"OPG164: S7L; OPG193: S221F"}}},{"name":"OQ957072","node_attrs":{"div":68,"accession":"OQ957072","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain":{"value":"ANT-LDSP-ANT-MPX-3668E"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"strain_display":{"value":"Colombia/OQ957072/2023-02-16"},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2023-02-16"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["C35308T","G71777A","C120979T"],"OPG054":["R230H"],"OPG138":["D52N"]},"labels":{"aa":"OPG054: R230H; OPG138: D52N"}}},{"name":"OQ696094","node_attrs":{"div":68,"accession":"OQ696094","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain":{"value":"ANT-LDSP-ANT-MPX-30087C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OQ696094/2022-11-08"},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-11-08"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C42840T","C55000T","G67730A","C196739-","T196740-","T196741-"],"OPG073":["E48K"],"OPG085":["R268C"]},"labels":{"aa":"OPG073: E48K; OPG085: R268C"}}},{"name":"OR433614","node_attrs":{"div":66,"accession":"OR433614","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-094945/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR433614/2022-09-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["-607T","C89777T","T166110-","T166111-","A166112-","A166113-","T166114-","A166115-","A166116-"],"OPG110":["P49L"]},"labels":{"aa":"OPG110: P49L"}}},{"name":"OR095053","node_attrs":{"div":65,"accession":"OR095053","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_235/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR095053/2022-08-12"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-12"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OR464206","node_attrs":{"div":68,"accession":"OR464206","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_TN0020"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR464206/2022-12-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-12-XX"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["-607T","G19458A","G74374A","-179194A","-179195T","-179196A","-179197T","-179198A","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C185455T","-196615A"],"OPG034":["S183L"],"OPG094":["E199K"],"OPG210":["S1367L"]},"labels":{"aa":"OPG034: S183L; OPG094: E199K; OPG210: S1367L"}}}]},{"name":"NODE_0000104","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["G34308A"],"OPG053":["S128L"]},"labels":{"aa":"OPG053: S128L","clade":"B.1.4"}},"children":[{"name":"ON880519","node_attrs":{"div":63,"accession":"ON880519","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"strain":{"value":"MpxV/human/CAN/UN-NML-2833/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/ON880519/2022-05-13"},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-13"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["T85846C"],"OPG107":["M112T"]},"labels":{"aa":"OPG107: M112T"}}},{"name":"OQ121015","node_attrs":{"div":62,"accession":"OQ121015","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,Bell,J.,Hacker,J."},"strain":{"value":"hMpxV/USA/CA-CDPH-1000061/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ121015/2022-08-01"},"country":{"value":"USA"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["G610-","T611-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"NODE_0000105","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["C10672T","G112481A","G163626A"],"OPG022":["E63K"]},"labels":{"aa":"OPG022: E63K"}},"children":[{"name":"OR126132","node_attrs":{"div":69,"accession":"OR126132","author":{"author":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C.","value":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C."},"strain":{"value":"HRYC_MPXV002"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Spain/OR126132/2023-03-23"},"country":{"value":"Spain"},"institution":{"value":"Hospital Ramon y Cajal, Microbiology"},"date":{"value":"2023-03-23"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["G6376A","G11924A","G21674A","A87705G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C190834T"],"OPG016":["S142L"],"OPG023":["S326L"],"OPG037":["L254F"]},"labels":{"aa":"OPG016: S142L; OPG023: S326L; OPG037: L254F"}}},{"name":"NODE_0000106","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["G144478A"]}},"children":[{"name":"ON880511","node_attrs":{"div":66,"accession":"ON880511","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"strain":{"value":"MpxV/human/CAN/UN-NML-3214/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/ON880511/2022-05-30"},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-30"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{}}},{"name":"OR759176","node_attrs":{"div":69,"accession":"OR759176","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain":{"value":"hMpxV/Canada/ON-PHOL088/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OR759176/2022-09-01"},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["-607T","C128534T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C151626T","G170076A"],"OPG178":["Q40*"]},"labels":{"aa":"OPG178: Q40*"}}},{"name":"OR759168","node_attrs":{"div":67,"accession":"OR759168","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain":{"value":"hMpxV/Canada/ON-PHOL080/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OR759168/2022-08-01"},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["C4150T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G193060A"],"OPG003":["S153N"],"OPG003_dup":["S153N"]},"labels":{"aa":"OPG003: S153N; OPG003_dup: S153N"}}}]}]},{"name":"NODE_0000107","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["C24995T","G85774A","G148427A","G189258A"],"OPG040":["D162N"],"OPG107":["R88K"]},"labels":{"aa":"OPG040: D162N; OPG107: R88K"}},"children":[{"name":"ON983163","node_attrs":{"div":66,"accession":"ON983163","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"strain":{"value":"MpxV/human/CAN/UN-NML-3532/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/ON983163/2022-06-07"},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-07"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{}}},{"name":"ON880514","node_attrs":{"div":66,"accession":"ON880514","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"strain":{"value":"MpxV/human/CAN/UN-NML-3412/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/ON880514/2022-06-04"},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-04"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["-179189A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"]}}},{"name":"ON803413","node_attrs":{"div":66,"accession":"ON803413","author":{"author":"Knox,N.,Hole,D.,Duggan,A.,Yadav,C.,Haidl,E.,Chapel,M.,Graham,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Hagan,M.,Griffiths,E.,Leung,A.,Safronetz,D.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Knox,N.,Hole,D.,Duggan,A.,Yadav,C.,Haidl,E.,Chapel,M.,Graham,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Hagan,M.,Griffiths,E.,Leung,A.,Safronetz,D.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"strain":{"value":"MpxV/human/CAN/UN-NML-2928/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/ON803413/2022-05-21"},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-21"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP415246","node_attrs":{"div":68,"accession":"OP415246","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPX_J6xzTO_9000286"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP415246/2022-08-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["G45236A","G174962A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG204":["R144K"]},"labels":{"aa":"OPG204: R144K"}}},{"name":"OQ121037","node_attrs":{"div":66,"accession":"OQ121037","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,Bell,J.,Hacker,J."},"strain":{"value":"hMpxV/USA/CA-CDPH-1000083/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ121037/2022-06-13"},"country":{"value":"USA"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2022-06-13"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OR759226","node_attrs":{"div":68,"accession":"OR759226","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain":{"value":"hMpxV/Canada/ON-PHOL140/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OR759226/2022-07-01"},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-07-01"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["G20145A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G189924A"],"OPG035":["S87L"]},"labels":{"aa":"OPG035: S87L"}}}]},{"name":"NODE_0000108","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["G36259A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G174543A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}},"children":[{"name":"OP626135","node_attrs":{"div":67,"accession":"OP626135","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI496"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP626135/2022-09-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["C40251T","C154472T","G167517A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"],"OPG058":["D62N"],"OPG181":["H21Y"],"OPG193":["E62K"]},"labels":{"aa":"OPG058: D62N; OPG181: H21Y; OPG193: E62K"}}},{"name":"OP863227","node_attrs":{"div":64,"accession":"OP863227","author":{"author":"Haw,M.,Probert,W.,Espinosa,A.,Kath,C.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Haw,M.,Probert,W.,Espinosa,A.,Kath,C.,O'Neil,R.,Bell,J.,Hacker,J."},"strain":{"value":"hMpxV/USA/CA-CDPH-000052/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP863227/2022-07-21"},"country":{"value":"USA"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2022-07-21"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{}}},{"name":"OQ547900","node_attrs":{"div":66,"accession":"OQ547900","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000185/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ547900/2022-12-21"},"country":{"value":"USA"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2022-12-21"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["T6976-","G92733A","C177720T"],"OPG113":["E335K"],"OPG205":["R689C"]},"labels":{"aa":"OPG113: E335K; OPG205: R689C"}}},{"name":"NODE_0000109","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["C25967T"],"OPG042":["W377*"]},"labels":{"aa":"OPG042: W377*"}},"children":[{"name":"OP681776","node_attrs":{"div":65,"accession":"OP681776","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-096851/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP681776/2022-09-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["T13207-","A13208-","C13209-","T13210-","A13211-","C13212-","C13213-","C13214-","C13215-","C13216-","T13217-","T13218-","T13219-","A13220-","G13221-","A13222-","C13223-","G13224-","A13225-","C13226-","A13227-","T13228-","A13229-","T13230-","T13231-","A13232-","A13233-","T13234-","A13235-","A13236-","G13237-","A13238-","C13239-","A13240-","A13241-","G13242-","T13243-","T13244-","T13245-","A13246-","A13247-","C13248-","A13249-","A13250-","T13251-","A13252-","A13253-","A13254-","A13255-","T13256-","T13257-","A13258-","A13259-","T13260-","C13261-","A13262-","C13263-","G13264-","A13265-","G13266-","T13267-","A13268-","C13269-","C13270-","C13271-","T13272-","A13273-","C13274-","T13275-","A13276-","C13277-","C13278-","A13279-","A13280-","C13281-","C13282-","A13283-","C13284-","T13285-","A13286-","T13287-","T13288-","A13289-","T13290-","A13291-","T13292-","G13293-","A13294-","T13295-","T13296-","A13297-","C13298-","A13299-","G13300-","T13301-","A13302-","C13303-","C13304-","T13305-","T13306-","G13307-","A13308-","C13309-","T13310-","A13311-","A13312-","A13313-","G13314-","T13315-","C13316-","T13317-","C13318-","T13319-","A13320-","G13321-","T13322-","C13323-","A13324-","C13325-","A13326-","A13327-","G13328-","A13329-","T13330-","C13331-","A13332-","A13333-","T13334-","A13335-","C13336-","T13337-","A13338-","C13339-","C13340-","A13341-","A13342-","C13343-","C13344-","T13345-","A13346-","C13347-","G13348-","C13349-","T13350-","A13351-","T13352-","T13353-","A13354-","T13355-","A13356-","T13357-","G13358-","A13359-","T13360-","T13361-","A13362-","T13363-","A13364-","G13365-","T13366-","T13367-","T13368-","C13369-","T13370-","A13371-","T13372-","T13373-","T13374-","T13375-","T13376-","A13377-","T13378-","A13379-","G13380-","G13381-","A13382-","A13383-","C13384-","G13385-","C13386-","G13387-","T13388-","A13389-","C13390-","G13391-","A13392-","G13393-","A13394-","A13395-","A13396-","A13397-","T13398-","C13399-","A13400-","A13401-","A13402-","T13403-","G13404-","T13405-","C13406-","T13407-","A13408-","A13409-","G13410-","T13411-","T13412-","C13413-","T13414-","A13415-","A13416-","C13417-","G13418-","G13419-","T13420-","A13421-","G13422-","T13423-","G13424-","T13425-","T13426-","G13427-","A13428-","T13429-","A13430-","A13431-","A13432-","C13433-","G13434-","A13435-","T13436-","T13437-","G13438-","T13439-","T13440-","A13441-","T13442-","C13443-","C13444-","G13445-","C13446-","G13447-","G13448-","A13449-","T13450-","A13451-","C13452-","C13453-","T13454-","C13455-","A13456-","T13457-","C13458-","T13459-","A13460-","T13461-","C13462-","A13463-","T13464-","G13465-","T13466-","T13467-","G13468-","T13469-","C13470-","T13471-","A13472-","T13473-","T13474-","T13475-","T13476-","C13477-","T13478-","T13479-","A13480-","C13481-","T13482-","T13483-","T13484-","G13485-","T13486-","T13487-","C13488-","T13489-","A13490-","T13491-","T13492-","A13493-","A13494-","C13495-","C13496-","T13497-","A13498-","T13499-","T13500-","A13501-","G13502-","C13503-","A13504-","T13505-","T13506-","A13507-","T13508-","A13509-","T13510-","A13511-","T13512-","T13513-","A13514-","T13515-","T13516-","T13517-","G13518-","A13519-","T13520-","T13521-","A13522-","T13523-","A13524-","A13525-","A13526-","A13527-","C13528-","T13529-","T13530-","A13531-","T13532-","A13533-","T13534-","T13535-","G13536-","C13537-","T13538-","T13539-","A13540-","T13541-","T13542-","A13543-","G13544-","C13545-","C13546-","C13547-","A13548-","A13549-","T13550-","C13551-","T13552-","G13553-","T13554-","A13555-","A13556-","A13557-","T13558-","A13559-","T13560-","C13561-","G13562-","G13563-","A13564-","T13565-","T13566-","A13567-","T13568-","T13569-","A13570-","A13571-","C13572-","A13573-","T13574-","A13575-","T13576-","C13577-","G13578-","T13579-","T13580-","T13581-","C13582-","T13583-","T13584-","T13585-","G13586-","T13587-","A13588-","G13589-","G13590-","T13591-","T13592-","T13593-","A13594-","T13595-","T13596-","T13597-","A13598-","A13599-","C13600-","T13601-","T13602-","G13603-","T13604-","A13605-","C13606-","A13607-","T13608-","C13609-","A13610-","C13611-","T13612-","G13613-","T13614-","A13615-","A13616-","G13617-","C13618-","A13619-","T13620-","G13621-","T13622-","C13623-","C13624-","G13625-","T13626-","A13627-","C13628-","C13629-","A13630-","T13631-","T13632-","T13633-","A13634-","T13635-","T13636-","T13637-","T13638-","A13639-","A13640-","T13641-","T13642-","T13643-","G13644-","A13645-","C13646-","A13647-","C13648-","A13649-","T13650-","A13651-","T13652-","C13653-","A13654-","G13655-","C13656-","A13657-","A13658-","T13659-","T13660-","T13661-","C13662-","T13663-","T13664-","T13665-","T13666-","T13667-","C13668-","G13669-","C13670-","A13671-","G13672-","T13673-","C13674-","G13675-","G13676-","T13677-","T13678-","A13679-","T13680-","A13681-","T13682-","A13683-","T13684-","T13685-","C13686-","T13687-","A13688-","T13689-","A13690-","T13691-","A13692-","A13693-","G13694-","A13695-","T13696-","G13697-","G13698-","A13699-","T13700-","A13701-","C13702-","G13703-","T13704-","A13705-","T13706-","C13707-","A13708-","C13709-","A13710-","T13711-","A13712-","T13713-","G13714-","T13715-","A13716-","C13717-","T13718-","T13719-","A13720-","T13721-","A13722-","G13723-","T13724-","C13725-","T13726-","A13727-","C13728-","T13729-","A13730-","A13731-","T13732-","A13733-","T13734-","G13735-","A13736-","A13737-","G13738-","T13739-","A13740-","C13741-","T13742-","T13743-","A13744-","A13745-","T13746-","A13747-","C13748-","A13749-","T13750-","A13751-","T13752-","T13753-","T13754-","T13755-","C13756-","A13757-","G13758-","T13759-","A13760-","A13761-","C13762-","G13763-","A13764-","T13765-","T13766-","T13767-","A13768-","G13769-","C13770-","C13771-","T13772-","T13773-","A13774-","T13775-","T13776-","A13777-","C13778-","C13779-","T13780-","A13781-","T13782-","T13783-","A13784-","A13785-","T13786-","A13787-","A13788-","G13789-","T13790-","G13791-","C13792-","C13793-","T13794-","G13795-","T13796-","C13797-","G13798-","T13799-","T13800-","G13801-","G13802-","A13803-","T13804-","A13805-","G13806-","G13807-","T13808-","A13809-","A13810-","T13811-","C13812-","A13813-","A13814-","C13815-","T13816-","G13817-","T13818-","T13819-","T13820-","T13821-","C13822-","T13823-","T13824-","A13825-","A13826-","T13827-","A13828-","C13829-","A13830-","T13831-","T13832-","C13833-","G13834-","A13835-","T13836-","G13837-","G13838-","T13839-","T13840-","G13841-","G13842-","T13843-","A13844-","A13845-","T13846-","T13847-","T13848-","A13849-","C13850-","T13851-","C13852-","A13853-","A13854-","A13855-","A13856-","T13857-","A13858-","A13859-","T13860-","T13861-","T13862-","C13863-","C13864-","A13865-","A13866-","T13867-","A13868-","T13869-","C13870-","T13871-","T13872-","A13873-","A13874-","T13875-","A13876-","T13877-","A13878-","T13879-","A13880-","T13881-","T13882-","T13883-","C13884-","T13885-","G13886-","C13887-","T13888-","A13889-","T13890-","T13891-","T13892-","C13893-","T13894-","G13895-","G13896-","T13897-","A13898-","T13899-","A13900-","C13901-","A13902-","T13903-","G13904-","C13905-","A13906-","T13907-","G13908-","T13909-","G13910-","C13911-","C13912-","A13913-","T13914-","T13915-","A13916-","T13917-","A13918-","A13919-","C13920-","A13921-","C13922-","A13923-","A13924-","A13925-","T13926-","A13927-","C13928-","C13929-","A13930-","A13931-","T13932-","A13933-","C13934-","A13935-","T13936-","G13937-","T13938-","A13939-","G13940-","A13941-","C13942-","C13943-","C13944-","A13945-","T13946-","A13947-","T13948-","G13949-","T13950-","T13951-","G13952-","T13953-","T13954-","G13955-","T13956-","T13957-","A13958-","T13959-","A13960-","T13961-","T13962-","A13963-","A13964-","T13965-","A13966-","T13967-","C13968-","T13969-","G13970-","C13971-","G13972-","C13973-","C13974-","A13975-","T13976-","T13977-","A13978-","T13979-","C13980-","T13981-","A13982-","T13983-","T13984-","A13985-","A13986-","C13987-","C13988-","A13989-","T13990-","T13991-","C13992-","T13993-","A13994-","T13995-","T13996-","A13997-","G13998-","G13999-","T14000-","C14001-","A14002-","A14003-","C14004-","A14005-","C14006-","T14007-","A14008-","T14009-","G14010-","C14011-","G14012-","A14013-","C14014-","T14015-","C14016-","G14017-","A14018-","T14019-","A14020-","C14021-","A14022-","A14023-","T14024-","A14025-","A14026-","T14027-","A14028-","A14029-","A14030-","G14031-","T14032-","A14033-","T14034-","A14035-","C14036-","T14037-","A14038-","C14039-","G14040-","T14041-","C14042-","C14043-","A14044-","T14045-","G14046-","T14047-","T14048-","T14049-","A14050-","T14051-","C14052-","T14053-","A14054-","T14055-","T14056-","T14057-","T14058-","G14059-","T14060-","T14061-","T14062-","A14063-","T14064-","A14065-","T14066-","C14067-","A14068-","T14069-","C14070-","G14071-","A14072-","T14073-","A14074-","T14075-","A14076-","C14077-","G14078-","G14079-","C14080-","T14081-","T14082-","A14083-","C14084-","A14085-","A14086-","A14087-","T14088-","T14089-","T14090-","C14091-","T14092-","A14093-","G14094-","T14095-","A14096-","T14097-","C14098-","G14099-","A14100-","T14101-","A14102-","A14103-","C14104-","A14105-","C14106-","T14107-","T14108-","C14109-","T14110-","G14111-","A14112-","C14113-","T14114-","C14115-","G14116-","T14117-","G14118-","A14119-","A14120-","T14121-","A14122-","A14123-","A14124-","T14125-","A14126-","A14127-","G14128-","G14129-","T14130-","A14131-","G14132-","G14133-","G14134-","A14135-","A14136-","T14137-","A14138-","A14139-","C14140-","G14141-","G14142-","C14143-","A14144-","T14145-","A14146-","A14147-","T14148-","A14149-","T14150-","T14151-","T14152-","A14153-","T14154-","T14155-","A14156-","T14157-","G14158-","T14159-","T14160-","A14161-","T14162-","C14163-","A14164-","T14165-","C14166-","A14167-","T14168-","T14169-","A14170-","A14171-","C14172-","A14173-","A14174-","C14175-","T14176-","A14177-","C14178-","G14179-","T14180-","T14181-","T14182-","C14183-","C14184-","A14185-","T14186-","T14187-","T14188-","T14189-","T14190-","T14191-","A14192-","A14193-","A14194-","A14195-","T14196-","A14197-","T14198-","A14199-","C14200-","T14201-","C14202-","T14203-","A14204-","C14205-","A14206-","A14207-","C14208-","T14209-","T14210-","T14211-","A14212-","G14213-","G14214-","A14215-","T14216-","C14217-","C14218-","C14219-","T14220-","A14221-","T14222-","T14223-","G14224-","T14225-","C14226-","A14227-","A14228-","A14229-","T14230-","C14231-","T14232-","T14233-","T14234-","T14235-","A14236-","A14237-","A14238-","A14239-","T14240-","A14241-","T14242-","T14243-","T14244-","A14245-","T14246-","T14247-","T14248-","A14249-","T14250-","A14251-","T14252-","G14253-","C14254-","T14255-","T14256-","A14257-","A14258-","A14259-","T14260-","C14261-","T14262-","A14263-","T14264-","A14265-","T14266-","A14267-","A14268-","T14269-","A14270-","T14271-","A14272-","G14273-","C14274-","T14275-","C14276-","C14277-","T14278-","T14279-","C14280-","C14281-","C14282-","T14283-","A14284-","A14285-","T14286-","C14287-","A14288-","T14289-","A14290-","C14291-","A14292-","T14293-","T14294-","T14295-","G14296-","A14297-","T14298-","A14299-","A14300-","C14301-","A14302-","T14303-","T14304-","G14305-","A14306-","T14307-","G14308-","T14309-","A14310-","C14311-","A14312-","C14313-","T14314-","G14315-","T14316-","A14317-","T14318-","G14319-","A14320-","T14321-","A14322-","A14323-","G14324-","A14325-","T14326-","A14327-","C14328-","A14329-","T14330-","A14331-","T14332-","T14333-","C14334-","T14335-","G14336-","A14337-","C14338-","A14339-","A14340-","T14341-","A14342-","G14343-","A14344-","T14345-","C14346-","T14347-","T14348-","G14349-","T14350-","A14351-","T14352-","A14353-","G14354-","A14355-","A14356-","T14357-","C14358-","T14359-","G14360-","T14361-","A14362-","T14363-","A14364-","T14365-","C14366-","T14367-","T14368-","T14369-","T14370-","A14371-","A14372-","G14373-","A14374-","A14375-","T14376-","T14377-","G14378-","A14379-","G14380-","G14381-","A14382-","T14383-","A14384-","T14385-","T14386-","A14387-","T14388-","G14389-","A14390-","C14391-","A14392-","T14393-","T14394-","A14395-","T14396-","T14397-","A14398-","C14399-","G14400-","T14401-","A14402-","A14403-","A14404-","C14405-","T14406-","A14407-","T14408-","T14409-","A14410-","C14411-","A14412-","C14413-","A14414-","A14415-","T14416-","T14417-","C14418-","T14419-","A14420-","A14421-","A14422-","A14423-","T14424-","A14425-","T14426-","A14427-","A14428-","A14429-","A14430-","T14431-","G14432-","T14433-","A14434-","T14435-","C14436-","A14437-","T14438-","G14439-","G14440-","G14441-","C14442-","A14443-","G14444-","A14445-","T14446-","A14447-","A14448-","T14449-","A14450-","G14451-","T14452-","T14453-","T14454-","A14455-","T14456-","C14457-","C14458-","A14459-","C14460-","T14461-","A14462-","T14463-","A14464-","T14465-","A14466-","A14467-","T14468-","T14469-","A14470-","T14471-","C14472-","T14473-","A14474-","T14475-","T14476-","T14477-","T14478-","A14479-","T14480-","G14481-","A14482-","T14483-","T14484-","T14485-","T14486-","T14487-","C14488-","T14489-","T14490-","C14491-","C14492-","T14493-","A14494-","T14495-","A14496-","T14497-","T14498-","G14499-","T14500-","T14501-","T14502-","A14503-","C14504-","G14505-","T14506-","A14507-","A14508-","A14509-","T14510-","A14511-","G14512-","A14513-","T14514-","A14515-","G14516-","A14517-","T14518-","A14519-","G14520-","A14521-","A14522-","T14523-","A14524-","T14525-","G14526-","C14527-","A14528-","T14529-","T14530-","A14531-","G14532-","T14533-","T14534-","C14535-","A14536-","T14537-","T14538-","A14539-","C14540-","C14541-","G14542-","C14543-","T14544-","A14545-","T14546-","A14547-","G14548-","T14549-","T14550-","A14551-","C14552-","T14553-","A14554-","T14555-","C14556-","G14557-","A14558-","A14559-","T14560-","A14561-","A14562-","C14563-","A14564-","C14565-","G14566-","T14567-","C14568-","A14569-","A14570-","A14571-","T14572-","A14573-","T14574-","T14575-","T14576-","C14577-","C14578-","C14579-","G14580-","T14581-","T14582-","T14583-","A14584-","A14585-","T14586-","A14587-","T14588-","C14589-","G14590-","C14591-","A14592-","T14593-","T14594-","T14595-","G14596-","T14597-","C14598-","A14599-","A14600-","C14601-","A14602-","T14603-","A14604-","A14605-","T14606-","A14607-","A14608-","T14609-","A14610-","G14611-","A14612-","G14613-","T14614-","A14615-","T14616-","G14617-","G14618-","T14619-","A14620-","C14621-","G14622-","T14623-","T14624-","C14625-","A14626-","C14627-","G14628-","A14629-","T14630-","A14631-","A14632-","G14633-","T14634-","A14635-","T14636-","A14637-","A14638-","T14639-","G14640-","A14641-","C14642-","A14643-","C14644-","A14645-","T14646-","C14647-","T14648-","C14649-","G14650-","T14651-","T14652-","T14653-","T14654-","C14655-","G14656-","T14657-","G14658-","C14659-","G14660-","A14661-","A14662-","A14663-","T14664-","T14665-","A14666-","A14667-","A14668-","T14669-","A14670-","G14671-","T14672-","T14673-","T14674-","A14675-","T14676-","C14677-","A14678-","C14679-","G14680-","T14681-","C14682-","C14683-","A14684-","A14685-","A14686-","G14687-","A14688-","T14689-","G14690-","T14691-","C14692-","A14693-","C14694-","A14695-","T14696-","A14697-","A14698-","C14699-","C14700-","A14701-","T14702-","C14703-","T14704-","T14705-","G14706-","T14707-","G14708-","A14709-","C14710-","C14711-","T14712-","A14713-","G14714-","T14715-","A14716-","A14717-","T14718-","A14719-","A14720-","T14721-","A14722-","T14723-","A14724-","A14725-","T14726-","A14727-","A14728-","T14729-","A14730-","G14731-","A14732-","G14733-","A14734-","A14735-","C14736-","T14737-","G14738-","T14739-","T14740-","T14741-","T14742-","A14743-","C14744-","C14745-","C14746-","A14747-","T14748-","T14749-","C14750-","T14751-","A14752-","T14753-","T14754-","A14755-","T14756-","C14757-","A14758-","T14759-","A14760-","A14761-","T14762-","C14763-","A14764-","G14765-","T14766-","G14767-","G14768-","T14769-","G14770-","T14771-","A14772-","G14773-","T14774-","C14775-","A14776-","T14777-","A14778-","A14779-","T14780-","C14781-","T14782-","A14783-","A14784-","A14785-","T14786-","A14787-","A14788-","T14789-","C14790-","A14791-","A14792-","A14793-","C14794-","T14795-","C14796-","G14797-","T14798-","C14799-","A14800-","T14801-","C14802-","C14803-","C14804-","A14805-","A14806-","T14807-","T14808-","A14809-","A14810-","A14811-","A14812-","T14813-","A14814-","A14815-","A14816-","T14817-","A14818-","T14819-","A14820-","A14821-","T14822-","C14823-","A14824-","G14825-","T14826-","A14827-","C14828-","A14829-","T14830-","T14831-","G14832-","A14833-","A14834-","T14835-","G14836-","G14837-","G14838-","T14839-","A14840-","T14841-","G14842-","A14843-","T14844-","A14845-","T14846-","T14847-","G14848-","T14849-","A14850-","C14851-","C14852-","C14853-","A14854-","T14855-","A14856-","C14857-","T14858-","G14859-","T14860-","A14861-","T14862-","G14863-","T14864-","T14865-","G14866-","C14867-","T14868-","A14869-","C14870-","A14871-","T14872-","G14873-","T14874-","A14875-","G14876-","G14877-","T14878-","A14879-","T14880-","T14881-","C14882-","C14883-","T14884-","T14885-","T14886-","A14887-","T14888-","C14889-","C14890-","A14891-","A14892-","T14893-","A14894-","A14895-","T14896-","A14897-","G14898-","T14899-","T14900-","T14901-","A14902-","A14903-","A14904-","T14905-","A14906-","C14907-","A14908-","T14909-","C14910-","T14911-","A14912-","T14913-","A14914-","T14915-","T14916-","A14917-","G14918-","G14919-","A14920-","T14921-","T14922-","T14923-","G14924-","A14925-","T14926-","G14927-","T14928-","T14929-","G14930-","T14931-","C14932-","G14933-","C14934-","G14935-","T14936-","A14937-","T14938-","T14939-","T14940-","C14941-","T14942-","C14943-","T14944-","A14945-","C14946-","A14947-","A14948-","T14949-","A14950-","T14951-","T14952-","A14953-","A14954-","T14955-","A14956-","C14957-","C14958-","A14959-","T14960-","T14961-","T14962-","T14963-","T14964-","G14965-","A14966-","T14967-","A14968-","C14969-","T14970-","A14971-","T14972-","T14973-","T14974-","A14975-","T14976-","T14977-","T14978-","C14979-","T14980-","A14981-","T14982-","A14983-","C14984-","C14985-","T14986-","T14987-","T14988-","C14989-","G14990-","A14991-","A14992-","A14993-","T14994-","T14995-","A14996-","G14997-","T14998-","A14999-","A15000-","T15001-","T15002-","T15003-","C15004-","A15005-","A15006-","T15007-","A15008-","A15009-","G15010-","T15011-","C15012-","T15013-","A15014-","T15015-","A15016-","T15017-","C15018-","G15019-","A15020-","T15021-","G15022-","T15023-","T15024-","A15025-","T15026-","C15027-","A15028-","G15029-","A15030-","A15031-","C15032-","A15033-","T15034-","A15035-","G15036-","A15037-","T15038-","A15039-","T15040-","T15041-","C15042-","A15043-","A15044-","A15045-","T15046-","A15047-","T15048-","A15049-","T15050-","C15051-","A15052-","A15053-","A15054-","A15055-","T15056-","C15057-","A15058-","T15059-","T15060-","G15061-","A15062-","T15063-","A15064-","T15065-","T15066-","T15067-","T15068-","T15069-","A15070-","T15071-","A15072-","G15073-","T15074-","C15075-","G15076-","A15077-","C15078-","T15079-","G15080-","A15081-","C15082-","G15083-","A15084-","C15085-","A15086-","A15087-","T15088-","A15089-","A15090-","C15091-","A15092-","A15093-","A15094-","A15095-","T15096-","C15097-","A15098-","C15099-","A15100-","A15101-","C15102-","A15103-","T15104-","C15105-","G15106-","T15107-","T15108-","T15109-","T15110-","T15111-","G15112-","A15113-","T15114-","A15115-","T15116-","T15117-","A15118-","T15119-","T15120-","A15121-","T15122-","T15123-","T15124-","T15125-","T15126-","T15127-","T15128-","T15129-","G15130-","G15131-","T15132-","A15133-","A15134-","C15135-","G15136-","T15137-","A15138-","T15139-","G15140-","C15141-","C15142-","T15143-","T15144-","T15145-","A15146-","A15147-","T15148-","G15149-","G15150-","A15151-","G15152-","T15153-","T15154-","T15155-","C15156-","A15157-","C15158-","C15159-","A15160-","T15161-","C15162-","A15163-","T15164-","A15165-","C15166-","T15167-","C15168-","A15169-","T15170-","A15171-","T15172-","A15173-","A15174-","T15175-","G15176-","G15177-","A15178-","T15179-","T15180-","T15181-","G15182-","C15183-","A15184-","C15185-","C15186-","A15187-","C15188-","T15189-","T15190-","T15191-","C15192-","T15193-","A15194-","T15195-","T15196-","A15197-","A15198-","T15199-","G15200-","A15201-","T15202-","T15203-","G15204-","T15205-","G15206-","C15207-","A15208-","C15209-","T15210-","A15211-","C15212-","T15213-","G15214-","G15215-","C15216-","A15217-","T15218-","C15219-","G15220-","A15221-","T15222-","G15223-","T15224-","T15225-","A15226-","A15227-","A15228-","T15229-","G15230-","T15231-","T15232-","T15233-","T15234-","A15235-","C15236-","A15237-","A15238-","C15239-","T15240-","A15241-","T15242-","C15243-","A15244-","T15245-","A15246-","G15247-","A15248-","G15249-","T15250-","A15251-","T15252-","C15253-","T15254-","T15255-","A15256-","T15257-","C15258-","G15259-","T15260-","T15261-","A15262-","A15263-","C15264-","C15265-","A15266-","T15267-","G15268-","A15269-","T15270-","T15271-","G15272-","G15273-","T15274-","T15275-","G15276-","T15277-","T15278-","G15279-","A15280-","T15281-","G15282-","T15283-","T15284-","A15285-","T15286-","C15287-","A15288-","C15289-","A15290-","T15291-","T15292-","T15293-","T15294-","T15295-","T15296-","G15297-","G15298-","T15299-","T15300-","T15301-","C15302-","T15303-","T15304-","T15305-","C15306-","A15307-","T15308-","T15309-","T15310-","C15311-","A15312-","G15313-","T15314-","T15315-","A15316-","T15317-","G15318-","T15319-","A15320-","T15321-","G15322-","G15323-","A15324-","T15325-","T15326-","T15327-","A15328-","G15329-","C15330-","A15331-","C15332-","G15333-","T15334-","T15335-","T15336-","G15337-","G15338-","G15339-","A15340-","A15341-","G15342-","C15343-","A15344-","T15345-","G15346-","A15347-","G15348-","C15349-","T15350-","C15351-","A15352-","T15353-","A15354-","T15355-","G15356-","A15357-","T15358-","T15359-","T15360-","C15361-","A15362-","G15363-","T15364-","A15365-","C15366-","T15367-","G15368-","T15369-","A15370-","G15371-","T15372-","G15373-","T15374-","C15375-","A15376-","G15377-","T15378-","A15379-","C15380-","T15381-","A15382-","T15383-","T15384-","A15385-","G15386-","T15387-","T15388-","T15389-","C15390-","G15391-","A15392-","T15393-","C15394-","A15395-","G15396-","A15397-","T15398-","C15399-","A15400-","A15401-","T15402-","G15403-","T15404-","C15405-","T15406-","A15407-","G15408-","A15409-","T15410-","C15411-","T15412-","A15413-","T15414-","A15415-","G15416-","A15417-","A15418-","T15419-","C15420-","A15421-","A15422-","A15423-","A15424-","C15425-","A15426-","C15427-","A15428-","A15429-","T15430-","A15431-","G15432-","G15433-","T15434-","C15435-","A15436-","G15437-","A15438-","A15439-","G15440-","A15441-","T15442-","A15443-","A15444-","T15445-","G15446-","A15447-","A15448-","T15449-","A15450-","T15451-","C15452-","T15453-","G15454-","T15455-","A15456-","C15457-","G15458-","C15459-","T15460-","T15461-","C15462-","T15463-","T15464-","C15465-","T15466-","T15467-","G15468-","T15469-","A15470-","C15471-","T15472-","G15473-","T15474-","A15475-","A15476-","C15477-","T15478-","T15479-","C15480-","T15481-","G15482-","G15483-","T15484-","T15485-","T15486-","T15487-","G15488-","T15489-","T15490-","A15491-","G15492-","A15493-","T15494-","G15495-","G15496-","T15497-","T15498-","G15499-","C15500-","A15501-","T15502-","C15503-","G15504-","T15505-","G15506-","C15507-","T15508-","T15509-","T15510-","A15511-","A15512-","C15513-","G15514-","T15515-","C15516-","A15517-","A15518-","T15519-","G15520-","G15521-","T15522-","A15523-","C15524-","A15525-","A15526-","A15527-","T15528-","T15529-","T15530-","T15531-","A15532-","T15533-","C15534-","C15535-","T15536-","C15537-","G15538-","C15539-","T15540-","T15541-","T15542-","G15543-","T15544-","G15545-","T15546-","A15547-","T15548-","A15549-","T15550-","C15551-","A15552-","T15553-","A15554-","T15555-","T15556-","C15557-","G15558-","T15559-","C15560-","T15561-","C15562-","T15563-","A15564-","G15565-","T15566-","A15567-","T15568-","A15569-","A15570-","A15571-","A15572-","T15573-","T15574-","C15575-","T15576-","A15577-","T15578-","A15579-","T15580-","T15581-","C15582-","A15583-","A15584-","A15585-","T15586-","T15587-","A15588-","T15589-","C15590-","A15591-","T15592-","G15593-","C15594-","G15595-","A15596-","T15597-","G15598-","T15599-","G15600-","T15601-","G15602-","T15603-","A15604-","C15605-","G15606-","C15607-","T15608-","A15609-","A15610-","C15611-","G15612-","G15613-","T15614-","A15615-","T15616-","C15617-","A15618-","A15619-","T15620-","A15621-","A15622-","A15623-","C15624-","G15625-","G15626-","A15627-","G15628-","C15629-","A15630-","C15631-","A15632-","G15633-","C15634-","A15635-","T15636-","T15637-","T15638-","A15639-","G15640-","T15641-","C15642-","A15643-","A15644-","C15645-","A15646-","G15647-","T15648-","A15649-","A15650-","T15651-","C15652-","C15653-","A15654-","A15655-","A15656-","A15657-","T15658-","T15659-","T15660-","T15661-","T15662-","T15663-","A15664-","A15665-","A15666-","G15667-","T15668-","A15669-","T15670-","A15671-","T15672-","C15673-","T15674-","T15675-","A15676-","A15677-","C15678-","G15679-","A15680-","A15681-","A15682-","G15683-","A15684-","A15685-","G15686-","T15687-","T15688-","G15689-","T15690-","C15691-","A15692-","T15693-","C15694-","G15695-","T15696-","T15697-","A15698-","G15699-","A15700-","G15701-","T15702-","G15703-","T15704-","G15705-","G15706-","T15707-","A15708-","A15709-","A15710-","T15711-","C15712-","A15713-","T15714-","T15715-","G15716-","T15717-","C15718-","T15719-","A15720-","C15721-","G15722-","G15723-","T15724-","A15725-","C15726-","T15727-","A15728-","G15729-","A15730-","T15731-","C15732-","C15733-","T15734-","C15735-","A15736-","T15737-","A15738-","A15739-","G15740-","T15741-","G15742-","T15743-","A15744-","T15745-","A15746-","T15747-","A15748-","T15749-","C15750-","T15751-","A15752-","G15753-","A15754-","G15755-","T15756-","A15757-","A15758-","T15759-","A15760-","T15761-","T15762-","T15763-","A15764-","A15765-","T15766-","T15767-","T15768-","A15769-","T15770-","C15771-","A15772-","A15773-","A15774-","T15775-","G15776-","G15777-","T15778-","T15779-","G15780-","A15781-","T15782-","A15783-","A15784-","T15785-","A15786-","T15787-","G15788-","G15789-","A15790-","T15791-","G15792-","T15793-","T15794-","G15795-","T15796-","G15797-","G15798-","C15799-","A15800-","A15801-","T15802-","T15803-","T15804-","C15805-","C15806-","T15807-","A15808-","A15809-","T15810-","A15811-","C15812-","G15813-","G15814-","A15815-","A15816-","A15817-","T15818-","A15819-","A15820-","G15821-","A15822-","C15823-","A15824-","T15825-","A15826-","A15827-","A15828-","C15829-","A15830-","C15831-","G15832-","C15833-","A15834-","A15835-","T15836-","A15837-","A15838-","A15839-","T15840-","C15841-","T15842-","A15843-","A15844-","T15845-","T15846-","G15847-","C15848-","G15849-","G15850-","A15851-","C15852-","A15853-","T15854-","G15855-","T15856-","T15857-","A15858-","C15859-","A15860-","C15861-","T15862-","C15863-","C15864-","T15865-","T15866-","A15867-","A15868-","A15869-","A15870-","A15871-","A15872-","T15873-","A15874-","C15875-","G15876-","A15877-","A15878-","T15879-","A15880-","A15881-","A15882-","C15883-","A15884-","C15885-","T15886-","T15887-","T15888-","G15889-","G15890-","C15891-","T15892-","T15893-","T15894-","T15895-","A15896-","G15897-","T15898-","A15899-","A15900-","G15901-","T15902-","G15903-","T15904-","C15905-","A15906-","T15907-","T15908-","T15909-","A15910-","A15911-","C15912-","A15913-","C15914-","T15915-","A15916-","T15917-","A15918-","C15919-","T15920-","C15921-","A15922-","T15923-","A15924-","T15925-","T15926-","A15927-","A15928-","T15929-","C15930-","C15931-","A15932-","T15933-","G15934-","G15935-","A15936-","C15937-","T15938-","C15939-","A15940-","T15941-","A15942-","A15943-","T15944-","C15945-","T15946-","C15947-","T15948-","A15949-","T15950-","A15951-","C15952-","G15953-","G15954-","G15955-","A15956-","T15957-","T15958-","A15959-","A15960-","C15961-","G15962-","G15963-","A15964-","T15965-","G15966-","T15967-","T15968-","C15969-","T15970-","A15971-","T15972-","A15973-","T15974-","A15975-","C15976-","G15977-","G15978-","G15979-","G15980-","A15981-","T15982-","G15983-","A15984-","G15985-","T15986-","A15987-","G15988-","T15989-","T15990-","C15991-","T15992-","C15993-","T15994-","T15995-","C15996-","T15997-","T15998-","T15999-","A16000-","A16001-","C16002-","T16003-","T16004-","T16005-","A16006-","T16007-","A16008-","C16009-","T16010-","T16011-","T16012-","T16013-","T16014-","A16015-","C16016-","T16017-","A16018-","A16019-","T16020-","C16021-","A16022-","T16023-","A16024-","T16025-","T16026-","T16027-","A16028-","G16029-","A16030-","C16031-","T16032-","G16033-","A16034-","T16035-","G16036-","T16037-","A16038-","T16039-","G16040-","G16041-","G16042-","T16043-","A16044-","A16045-","T16046-","A16047-","G16048-","T16049-","G16050-","T16051-","T16052-","T16053-","G16054-","A16055-","A16056-","G16057-","A16058-","G16059-","C16060-","T16061-","C16062-","G16063-","T16064-","T16065-","C16066-","T16067-","C16068-","A16069-","T16070-","C16071-","A16072-","T16073-","C16074-","A16075-","G16076-","A16077-","A16078-","T16079-","A16080-","A16081-","A16082-","T16083-","C16084-","A16085-","A16086-","T16087-","A16088-","T16089-","C16090-","T16091-","C16092-","T16093-","G16094-","T16095-","T16096-","T16097-","T16098-","T16099-","T16100-","T16101-","G16102-","T16103-","T16104-","A16105-","T16106-","A16107-","C16108-","A16109-","G16110-","A16111-","T16112-","G16113-","T16114-","A16115-","T16116-","T16117-","A16118-","C16119-","A16120-","G16121-","C16122-","C16123-","T16124-","C16125-","A16126-","T16127-","A16128-","T16129-","A16130-","T16131-","T16132-","A16133-","C16134-","G16135-","T16136-","A16137-","A16138-","T16139-","A16140-","G16141-","A16142-","A16143-","C16144-","G16145-","T16146-","G16147-","T16148-","A16149-","A16150-","T16151-","C16152-","T16153-","A16154-","C16155-","C16156-","T16157-","T16158-","A16159-","T16160-","T16161-","A16162-","A16163-","C16164-","T16165-","T16166-","T16167-","C16168-","A16169-","C16170-","C16171-","G16172-","C16173-","A16174-","T16175-","A16176-","G16177-","T16178-","T16179-","G16180-","T16181-","T16182-","T16183-","G16184-","C16185-","A16186-","A16187-","A16188-","T16189-","A16190-","C16191-","G16192-","G16193-","T16194-","T16195-","A16196-","A16197-","T16198-","C16199-","C16200-","T16201-","T16202-","T16203-","G16204-","A16205-","C16206-","C16207-","T16208-","C16209-","G16210-","T16211-","C16212-","G16213-","A16214-","T16215-","T16216-","T16217-","C16218-","C16219-","G16220-","A16221-","C16222-","C16223-","A16224-","A16225-","T16226-","C16227-","T16228-","G16229-","G16230-","G16231-","C16232-","G16233-","T16234-","A16235-","T16236-","A16237-","A16238-","T16239-","G16240-","A16241-","A16242-","T16243-","C16244-","T16245-","T16246-","A16247-","A16248-","C16249-","T16250-","T16251-","T16252-","A16253-","A16254-","T16255-","T16256-","T16257-","C16258-","T16259-","T16260-","G16261-","T16262-","A16263-","A16264-","T16265-","C16266-","A16267-","T16268-","T16269-","C16270-","G16271-","A16272-","A16273-","A16274-","T16275-","A16276-","A16277-","T16278-","T16279-","T16280-","T16281-","T16282-","A16283-","G16284-","T16285-","T16286-","T16287-","G16288-","C16289-","A16290-","T16291-","C16292-","C16293-","G16294-","T16295-","A16296-","G16297-","T16298-","T16299-","A16300-","T16301-","C16302-","T16303-","C16304-","C16305-","T16306-","C16307-","T16308-","A16309-","T16310-","G16311-","T16312-","A16313-","A16314-","C16315-","T16316-","G16317-","T16318-","A16319-","A16320-","A16321-","T16322-","T16323-","T16324-","C16325-","T16326-","C16327-","A16328-","A16329-","C16330-","G16331-","C16332-","G16333-","A16334-","T16335-","A16336-","T16337-","C16338-","T16339-","C16340-","C16341-","A16342-","T16343-","T16344-","A16345-","A16346-","T16347-","A16348-","A16349-","T16350-","G16351-","A16352-","T16353-","G16354-","T16355-","C16356-","G16357-","A16358-","A16359-","T16360-","T16361-","C16362-","G16363-","T16364-","G16365-","T16366-","T16367-","G16368-","T16369-","A16370-","T16371-","A16372-","C16373-","C16374-","C16375-","A16376-","T16377-","A16378-","C16379-","T16380-","G16381-","A16382-","A16383-","T16384-","T16385-","G16386-","A16387-","T16388-","G16389-","A16390-","A16391-","C16392-","T16393-","A16394-","A16395-","T16396-","A16397-","C16398-","C16399-","G16400-","A16401-","C16402-","G16403-","G16404-","T16405-","A16406-","T16407-","T16408-","A16409-","A16410-","T16411-","A16412-","G16413-","T16414-","A16415-","A16416-","T16417-","T16418-","T16419-","A16420-","C16421-","T16422-","T16423-","T16424-","T16425-","C16426-","A16427-","T16428-","C16429-","T16430-","T16431-","T16432-","A16433-","C16434-","A16435-","T16436-","A16437-","C16438-","T16439-","T16440-","G16441-","G16442-","T16443-","A16444-","A16445-","T16446-","A16447-","G16448-","T16449-","T16450-","T16451-","T16452-","A16453-","C16454-","T16455-","A16456-","T16457-","C16458-","A16459-","T16460-","A16461-","A16462-","G16463-","T16464-","T16465-","T16466-","A16467-","T16468-","A16469-","A16470-","A16471-","T16472-","T16473-","C16474-","C16475-","A16476-","C16477-","A16478-","A16479-","G16480-","C16481-","T16482-","A16483-","C16484-","T16485-","A16486-","T16487-","G16488-","G16489-","A16490-","A16491-","T16492-","A16493-","T16494-","A16495-","C16496-","C16497-","A16498-","A16499-","C16500-","C16501-","A16502-","T16503-","C16504-","T16505-","T16506-","A16507-","G16508-","T16509-","A16510-","T16511-","A16512-","G16513-","A16514-","A16515-","C16516-","A16517-","C16518-","A16519-","T16520-","G16521-","T16522-","C16523-","T16524-","T16525-","A16526-","A16527-","A16528-","G16529-","T16530-","T16531-","A16532-","T16533-","T16534-","A16535-","A16536-","T16537-","T16538-","A16539-","A16540-","T16541-","T16542-","A16543-","C16544-","A16545-","T16546-","G16547-","T16548-","T16549-","G16550-","T16551-","T16552-","T16553-","T16554-","A16555-","T16556-","A16557-","T16558-","A16559-","T16560-","C16561-","G16562-","C16563-","T16564-","A16565-","C16566-","G16567-","A16568-","A16569-","T16570-","T16571-","T16572-","A16573-","A16574-","A16575-","C16576-","A16577-","G16578-","A16579-","G16580-","G16581-","A16582-","A16583-","T16584-","C16585-","A16586-","G16587-","T16588-","T16589-","A16590-","G16591-","G16592-","A16593-","A16594-","G16595-","A16596-","A16597-","A16598-","A16599-","A16600-","A16601-","T16602-","T16603-","A16604-","T16605-","C16606-","T16607-","G16608-","T16609-","C16610-","A16611-","T16612-","C16613-","A16614-","T16615-","C16616-","A16617-","T16618-","C16619-","A16620-","T16621-","C16622-","T16623-","A16624-","T16625-","T16626-","G16627-","G16628-","A16629-","T16630-","A16631-","A16632-","C16633-","A16634-","T16635-","C16636-","T16637-","C16638-","T16639-","G16640-","T16641-","A16642-","T16643-","T16644-","C16645-","T16646-","A16647-","C16648-","G16649-","A16650-","T16651-","A16652-","G16653-","A16654-","G16655-","T16656-","G16657-","C16658-","T16659-","A16660-","T16661-","T16662-","T16663-","T16664-","A16665-","A16666-","G16667-","A16668-","T16669-","G16670-","T16671-","G16672-","A16673-","C16674-","A16675-","G16676-","A16677-","T16678-","C16679-","C16680-","G16681-","T16682-","G16683-","T16684-","C16685-","A16686-","T16687-","C16688-","A16689-","A16690-","A16691-","T16692-","A16693-","T16694-","A16695-","T16696-","A16697-","C16698-","T16699-","C16700-","C16701-","A16702-","T16703-","T16704-","A16705-","A16706-","A16707-","A16708-","T16709-","G16710-","A16711-","T16712-","T16713-","A16714-","T16715-","T16716-","C16717-","C16718-","G16719-","G16720-","C16721-","A16722-","G16723-","C16724-","G16725-","A16726-","A16727-","C16728-","T16729-","T16730-","G16731-","A16732-","T16733-","A16734-","T16735-","T16736-","G16737-","G16738-","A16739-","T16740-","A16741-","C16742-","A16743-","T16744-","C16745-","A16746-","C16747-","G16748-","A16749-","C16750-","C16751-","T16752-","T16753-","T16754-","G16755-","T16756-","T16757-","A16758-","A16759-","T16760-","A16761-","T16762-","C16763-","C16764-","A16765-","C16766-","G16767-","A16768-","C16769-","A16770-","A16771-","T16772-","A16773-","G16774-","A16775-","C16776-","A16777-","G16778-","C16779-","A16780-","A16781-","T16782-","C16783-","C16784-","C16785-","A16786-","T16787-","T16788-","G16789-","T16790-","T16791-","C16792-","C16793-","A16794-","T16795-","A16796-","A16797-","A16798-","C16799-","A16800-","G16801-","T16802-","G16803-","A16804-","G16805-","T16806-","T16807-","T16808-","A16809-","T16810-","C16811-","T16812-","T16813-","T16814-","C16815-","T16816-","T16817-","T16818-","G16819-","A16820-","A16821-","G16822-","T16823-","G16824-","A16825-","T16826-","A16827-","T16828-","T16829-","T16830-","T16831-","G16832-","T16833-","A16834-","G16835-","A16836-","G16837-","A16838-","T16839-","C16840-","T16841-","T16842-","A16843-","T16844-","A16845-","A16846-","A16847-","A16848-","C16849-","T16850-","G16851-","T16852-","C16853-","G16854-","A16855-","A16856-","T16857-","G16858-","A16859-","C16860-","A16861-","T16862-","C16863-","G16864-","T16865-","A16866-","T16867-","T16868-","T16869-","A16870-","T16871-","A16872-","T16873-","C16874-","T16875-","T16876-","T16877-","A16878-","G16879-","C16880-","T16881-","A16882-","A16883-","A16884-","T16885-","C16886-","A16887-","T16888-","A16889-","T16890-","A16891-","T16892-","G16893-","T16894-","T16895-","A16896-","C16897-","C16898-","A16899-","T16900-","C16901-","A16902-","T16903-","A16904-","A16905-","T16906-","A16907-","T16908-","C16909-","T16910-","A16911-","A16912-","C16913-","A16914-","G16915-","C16916-","A16917-","T16918-","C16919-","T16920-","A16921-","T16922-","C16923-","T16924-","T16925-","A16926-","A16927-","A16928-","C16929-","G16930-","T16931-","T16932-","T16933-","C16934-","C16935-","A16936-","T16937-","C16938-","G16939-","C16940-","T16941-","G16942-","T16943-","A16944-","A16945-","A16946-","G16947-","A16948-","C16949-","G16950-","T16951-","T16952-","T16953-","C16954-","C16955-","G16956-","A16957-","T16958-","A16959-","G16960-","A16961-","T16962-","G16963-","G16964-","T16965-","C16966-","T16967-","C16968-","G16969-","T16970-","T16971-","T16972-","C16973-","A16974-","T16975-","C16976-","A16977-","G16978-","T16979-","C16980-","A16981-","T16982-","A16983-","C16984-","T16985-","G16986-","A16987-","G16988-","C16989-","C16990-","A16991-","A16992-","C16993-","A16994-","A16995-","A16996-","T16997-","G16998-","T16999-","A17000-","A17001-","T17002-","C17003-","G17004-","T17005-","G17006-","T17007-","A17008-","T17009-","A17010-","A17011-","C17012-","A17013-","T17014-","C17015-","T17016-","T17017-","T17018-","G17019-","A17020-","T17021-","A17022-","G17023-","A17024-","A17025-","T17026-","C17027-","A17028-","G17029-","A17030-","C17031-","T17032-","C17033-","T17034-","A17035-","A17036-","A17037-","G17038-","A17039-","A17040-","A17041-","A17042-","G17043-","G17044-","A17045-","A17046-","T17047-","C17048-","G17049-","G17050-","C17051-","T17052-","T17053-","T17054-","A17055-","T17056-","T17057-","A17058-","T17059-","A17060-","C17061-","A17062-","C17063-","A17064-","T17065-","T17066-","C17067-","A17068-","T17069-","G17070-","A17071-","T17072-","A17073-","A17074-","A17075-","C17076-","T17077-","T17078-","A17079-","A17080-","T17081-","G17082-","A17083-","A17084-","A17085-","A17086-","A17087-","T17088-","G17089-","T17090-","T17091-","T17092-","T17093-","T17094-","C17095-","G17096-","T17097-","T17098-","G17099-","T17100-","T17101-","T17102-","A17103-","A17104-","G17105-","T17106-","T17107-","G17108-","G17109-","A17110-","T17111-","G17112-","A17113-","A17114-","T17115-","A17116-","G17117-","T17118-","A17119-","T17120-","G17121-","T17122-","C17123-","T17124-","T17125-","A17126-","A17127-","T17128-","A17129-","A17130-","T17131-","T17132-","G17133-","T17134-","T17135-","A17136-","T17137-","T17138-","A17139-","T17140-","T17141-","T17142-","C17143-","A17144-","C17145-","T17146-","A17147-","A17148-","T17149-","T17150-","A17151-","A17152-","T17153-","A17154-","T17155-","T17156-","T17157-","A17158-","G17159-","T17160-","A17161-","A17162-","C17163-","G17164-","A17165-","G17166-","T17167-","A17168-","C17169-","A17170-","C17171-","T17172-","C17173-","T17174-","A17175-","T17176-","A17177-","A17178-","A17179-","A17180-","A17181-","C17182-","G17183-","A17184-","G17185-","A17186-","A17187-","T17188-","G17189-","A17190-","C17191-","A17192-","T17193-","A17194-","A17195-","C17196-","T17197-","A17198-","A17199-","T17200-","C17201-","A17202-","T17203-","A17204-","A17205-","C17206-","T17207-","A17208-","G17209-","T17210-","T17211-","A17212-","T17213-","C17214-","A17215-","A17216-","A17217-","G17218-","A17219-","A17220-","T17221-","G17222-","T17223-","C17224-","T17225-","A17226-","G17227-","G17228-","A17229-","C17230-","G17231-","C17232-","G17233-","T17234-","A17235-","A17236-","T17237-","T17238-","T17239-","T17240-","T17241-","T17242-","A17243-","T17244-","G17245-","G17246-","T17247-","A17248-","T17249-","A17250-","G17251-","A17252-","T17253-","C17254-","C17255-","T17256-","G17257-","T17258-","A17259-","A17260-","G17261-","C17262-","G17263-","T17264-","T17265-","G17266-","T17267-","C17268-","T17269-","G17270-","T17271-","A17272-","T17273-","T17274-","C17275-","T17276-","G17277-","G17278-","A17279-","G17280-","C17281-","T17282-","A17283-","T17284-","T17285-","T17286-","T17287-","C17288-","T17289-","C17290-","T17291-","A17292-","T17293-","C17294-","G17295-","C17296-","A17297-","T17298-","T17299-","A17300-","G17301-","T17302-","G17303-","A17304-","G17305-","T17306-","T17307-","C17308-","A17309-","G17310-","A17311-","A17312-","T17313-","A17314-","T17315-","G17316-","T17317-","T17318-","A17319-","T17320-","A17321-","A17322-","A17323-","T17324-","T17325-","T17326-","A17327-","A17328-","A17329-","T17330-","C17331-","G17332-","A17333-","A17334-","T17335-","A17336-","A17337-","C17338-","G17339-","A17340-","A17341-","C17342-","A17343-","T17344-","A17345-","A17346-","C17347-","T17348-","T17349-","T17350-","A17351-","G17352-","T17353-","A17354-","A17355-","A17356-","G17357-","T17358-","C17359-","G17360-","T17361-","C17362-","T17363-","A17364-","T17365-","A17366-","T17367-","T17368-","A17369-","A17370-","C17371-","T17372-","C17373-","T17374-","T17375-","T17376-","T17377-","A17378-","T17379-","T17380-","T17381-","T17382-","C17383-","T17384-","A17385-","G17386-","C17387-","C17388-","A17389-","T17390-","C17391-","G17392-","T17393-","A17394-","A17395-","T17396-","A17397-","C17398-","C17399-","A17400-","T17401-","G17402-","T17403-","T17404-","T17405-","A17406-","A17407-","G17408-","A17409-","T17410-","A17411-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP920681","node_attrs":{"div":67,"accession":"OP920681","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00343/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP920681/2022-11-10"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-11-10"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["A763-","A764-","T765-","C97805T","C172792T"],"OPG117":["P586L"]},"labels":{"aa":"OPG117: P586L"}}},{"name":"OQ503786","node_attrs":{"div":73,"accession":"OQ503786","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00452/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ503786/2022-10-12"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-10-12"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["G70435A","C125412T","C141442T","C141511T","G158709A","A163469T","G175698A","G176439A"],"OPG145":["S489L"],"OPG161":["S114L","S137F"],"OPG189":["E46V"],"OPG205":["D15N","D262N"]},"labels":{"aa":"OPG145: S489L; OPG161: S114L, S137F; OPG189: E46V; OPG205: D15N, D262N"}}}]}]}]},{"name":"NODE_0000110","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["G36617A","C159779T"],"OPG055":["S156L"],"OPG185":["S288L"]},"labels":{"aa":"OPG055: S156L; OPG185: S288L","clade":"B.1.14"}},"children":[{"name":"ON959169","node_attrs":{"div":65,"accession":"ON959169","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI155"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/ON959169/2022-07-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G168365A","G170929A"],"OPG195":["E46K"]},"labels":{"aa":"OPG195: E46K"}}},{"name":"ON959135","node_attrs":{"div":65,"accession":"ON959135","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_NY004"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/ON959135/2022-05-XX"},"country":{"value":"USA"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["T606-","G2132A","G96835A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C195078T","A196614-"],"OPG002":["S207L"],"OPG002_dup":["S207L"],"OPG117":["D263N"]},"labels":{"aa":"OPG002: S207L; OPG002_dup: S207L; OPG117: D263N"}}},{"name":"ON694342","node_attrs":{"div":63,"accession":"ON694342","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI011"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/ON694342/2022-05-XX"},"country":{"value":"Germany"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP378704","node_attrs":{"div":66,"accession":"OP378704","author":{"author":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y.","value":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y."},"strain":{"value":"MPXV_USA_2022_TX0010"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP378704/2022-06-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C8552T","C8597T","G46179A","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A","-196616A"],"OPG065":["S102L"]},"labels":{"aa":"OPG065: S102L"}}},{"name":"OP355569","node_attrs":{"div":64,"accession":"OP355569","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI310"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP355569/2022-08-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["C84008T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","A188351-"]}}},{"name":"OQ547752","node_attrs":{"div":64,"accession":"OQ547752","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI725"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ547752/2022-05-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["C3837T","G150551-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","G181052-"],"OPG209":["G179-"]},"labels":{"aa":"OPG209: G179-"}}},{"name":"OR035646","node_attrs":{"div":67,"accession":"OR035646","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_40"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR035646/2022-07-27"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-27"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["C22880T","G158617A","C170573T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C183790T"],"OPG038":["E94K"],"OPG198":["S179L"],"OPG210":["S812L"]},"labels":{"aa":"OPG038: E94K; OPG198: S179L; OPG210: S812L"}}},{"name":"OR449707","node_attrs":{"div":67,"accession":"OR449707","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI993"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OR449707/2022-06-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["C2459T","G90418A","C133943T","C134688T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG002":["R98Q"],"OPG111":["E52K"],"OPG193":["F263-"]},"labels":{"aa":"OPG002: R98Q; OPG111: E52K; OPG193: F263-"}}},{"name":"OX009124","node_attrs":{"div":65,"accession":"OX009124","author":{"author":"Pettke,A.,Filen,F.,Asgeirsson,H.,Glans,H.,Widgren,K.,Muradrasoli,S.,Helgesson,S.,Karlberg,M.L.,Walai,N.,Bjerkner,A.,Gourle,H.,Lindsjo,O.K.,Sonden,K.","value":"Pettke,A.,Filen,F.,Asgeirsson,H.,Glans,H.,Widgren,K.,Muradrasoli,S.,Helgesson,S.,Karlberg,M.L.,Walai,N.,Bjerkner,A.,Gourle,H.,Lindsjo,O.K.,Sonden,K."},"strain":{"value":"Lesion"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Sweden/OX009124/2022-05-22"},"country":{"value":"Sweden"},"institution":{"value":"Public Health Agency of Sweden, Unit for Laboratory Development and Technology Transfer , Folkhalsomyndigheten, 171 82 Solna"},"date":{"value":"2022-05-22"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["T602-","T603-","T604-","T605-","T606-","A8055-","A28529-","A28530-","T47054-","T76087-","T88836-","A91705-","A92907-","T103367-","T104687-","T148344A","A148345T","A151680-","A162904-","T163342-","T163597-","A170728-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG044":["K147-"],"OPG113":["I393-"],"OPG178":["T58-"],"OPG188":["K437-"],"OPG189":["F4-"],"OPG198":["K231-"]},"labels":{"aa":"OPG044: K147-; OPG113: I393-; OPG178: T58-; OPG188: K437-; OPG189: F4-; OPG198: K231-"}}},{"name":"NODE_0000111","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["G28021A"]}},"children":[{"name":"OP743966","node_attrs":{"div":67,"accession":"OP743966","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-099102/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP743966/2022-09-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["T606-","G18530A","G101152A","C167792T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG031":["S100F"]},"labels":{"aa":"OPG031: S100F"}}},{"name":"NODE_0000112","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["G181818A"],"OPG210":["A155T"]},"labels":{"aa":"OPG210: A155T"}},"children":[{"name":"OP539922","node_attrs":{"div":66,"accession":"OP539922","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00137/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP539922/2022-08-09"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-08-09"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["G109793A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G168211-","G168212-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP743362","node_attrs":{"div":66,"accession":"OP743362","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200104/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP743362/2022-07-21"},"country":{"value":"USA"},"institution":{"value":"Utah Public Health Laboratory"},"date":{"value":"2022-07-21"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["A19512C"],"OPG034":["I165R"]},"labels":{"aa":"OPG034: I165R"}}}]}]},{"name":"NODE_0000113","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["G171270A","-196615A"],"OPG199":["D95N"]},"labels":{"aa":"OPG199: D95N"}},"children":[{"name":"OP382492","node_attrs":{"div":65,"accession":"OP382492","author":{"author":"Colson,P.","value":"Colson,P."},"strain":{"value":"hMPXV-IHU00015"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"France/OP382492/2022-07-22"},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-22"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["T606-","G161913A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196856-","A196857-","A196858-"]}}},{"name":"OP494266","node_attrs":{"div":64,"accession":"OP494266","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI320"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP494266/2022-09-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OP605553","node_attrs":{"div":64,"accession":"OP605553","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain":{"value":"Slovenia-MPXV-10-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Slovenia/OP605553/2022-07-XX"},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","T196950-","A196951-","A196952-"]}}},{"name":"OP555644","node_attrs":{"div":66,"accession":"OP555644","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0573/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555644/2022-09-06"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-06"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","C93713T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G158549A","-196616T"]}}},{"name":"OP555575","node_attrs":{"div":64,"accession":"OP555575","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0501/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555575/2022-08-16"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-16"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR086995","node_attrs":{"div":65,"accession":"OR086995","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_186/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR086995/2022-08-03"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-03"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["G146441A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG170":["S113F"]},"labels":{"aa":"OPG170: S113F"}}}]}]},{"name":"NODE_0000114","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["G5595A","C191615T"],"OPG015":["Q188*"],"OPG015_dup":["Q188*"]},"labels":{"aa":"OPG015: Q188*; OPG015_dup: Q188*","clade":"B.1.8"}},"children":[{"name":"OP215224","node_attrs":{"div":62,"accession":"OP215224","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI235"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP215224/2022-08-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000115","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["G78034A","C80111T"],"OPG099":["D124N"]},"labels":{"aa":"OPG099: D124N"}},"children":[{"name":"ON622718","node_attrs":{"div":65,"accession":"ON622718","author":{"author":"Martinez-Puchol,S.,Coello,A.,Bordoy,A.E.,Soler,L.,Panisello,D.,Gonzalez-Gomez,S.,Clara,G.,Paris de Leon,A.,Not,A.,Hernandez,A.,Bofill-Mas,S.,Saludes,V.,Blanco,I.,Martro,E.,Cardona,P.-J.","value":"Martinez-Puchol,S.,Coello,A.,Bordoy,A.E.,Soler,L.,Panisello,D.,Gonzalez-Gomez,S.,Clara,G.,Paris de Leon,A.,Not,A.,Hernandez,A.,Bofill-Mas,S.,Saludes,V.,Blanco,I.,Martro,E.,Cardona,P.-J."},"strain":{"value":"MPXV/ES0001/HUGTiP/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Spain/ON622718/2022-05-20"},"country":{"value":"Spain"},"institution":{"value":"Microbiology, Hospital Universitari Germans Trias i Pujol, Spain"},"date":{"value":"2022-05-20"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C14113-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T139150C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","-196615A","-196616A"],"OPG156":["Q87R"]},"labels":{"aa":"OPG156: Q87R"}}},{"name":"NODE_0000116","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["G22643A","G63811A"],"OPG038":["H173Y"]},"labels":{"aa":"OPG038: H173Y"}},"children":[{"name":"OP415254","node_attrs":{"div":68,"accession":"OP415254","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPX_imBNaw_9000300"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP415254/2022-08-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["T119985C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G189258A"]}}},{"name":"OP390176","node_attrs":{"div":66,"accession":"OP390176","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"strain":{"value":"ATL-UNIMOL-MPX-292895-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP390176/2022-08-12"},"country":{"value":"Colombia"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"date":{"value":"2022-08-12"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP378705","node_attrs":{"div":66,"accession":"OP378705","author":{"author":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y.","value":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y."},"strain":{"value":"MPXV_USA_2022_TX0011"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP378705/2022-06-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP642374","node_attrs":{"div":67,"accession":"OP642374","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain":{"value":"ANT-LDSP-ANT-MPX-24722-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP642374/2022-09-08"},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-09-08"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["G168759A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG195":["R177K"]},"labels":{"aa":"OPG195: R177K"}}},{"name":"OP604531","node_attrs":{"div":67,"accession":"OP604531","author":{"author":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Knipe,K.,Burroughs,S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Knipe,K.,Burroughs,S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y."},"strain":{"value":"MPXV_USA_2022_FL0020"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP604531/2022-07-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C181695T"],"OPG210":["P114S"]},"labels":{"aa":"OPG210: P114S"}}},{"name":"OQ320513","node_attrs":{"div":70,"accession":"OQ320513","author":{"author":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y.","value":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y."},"strain":{"value":"MPXV_USA_2022_FL0009"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ320513/2022-10-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["G4038A","A39081T","C67289T","G73790A","T133102-","A173284-","T173285-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C193172T"],"OPG057":["I372N"],"OPG085":["E415K"],"OPG094":["G4E"]},"labels":{"aa":"OPG057: I372N; OPG085: E415K; OPG094: G4E"}}},{"name":"OR353588","node_attrs":{"div":70,"accession":"OR353588","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"strain":{"value":"MN-MDH-MPXV_0078"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR353588/2022-09-19"},"country":{"value":"USA"},"institution":{"value":"Minnesota Department of Health, Public Health Laboratory"},"date":{"value":"2022-09-19"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["A764-","T765-","T766-","G11462A","C111866T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G184562A","A190784G","C196797-","G196798-","T196799-"],"OPG023":["S480L"],"OPG130":["E13K"]},"labels":{"aa":"OPG023: S480L; OPG130: E13K"}}},{"name":"OR759149","node_attrs":{"div":70,"accession":"OR759149","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain":{"value":"hMpxV/Canada/ON-PHOL055/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OR759149/2022-08-01"},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["C8555T","G95862A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168089T","G181674A","-196615A"],"OPG116":["A168T"],"OPG210":["E107K"]},"labels":{"aa":"OPG116: A168T; OPG210: E107K"}}}]}]},{"name":"NODE_0000117","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["G161296A","-179172C","-179181C","-179190C","C196308T"],"OPG001_dup":["S225L"]},"labels":{"aa":"OPG001_dup: S225L"}},"children":[{"name":"OP331337","node_attrs":{"div":63,"accession":"OP331337","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPXV_UK_2022_9000183"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP331337/2022-06-29"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-29"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["G902A","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG001":["S225L"]},"labels":{"aa":"OPG001: S225L"}}},{"name":"OP555609","node_attrs":{"div":65,"accession":"OP555609","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0538/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555609/2022-08-23"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-23"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["-607T","G902A","C25269T","G25692A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","C179181-","C179190-"],"OPG001":["S225L"]},"labels":{"aa":"OPG001: S225L"}}},{"name":"OQ159046","node_attrs":{"div":68,"accession":"OQ159046","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI651"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ159046/2022-08-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["G2039A","G34298T","C37048T","G70190A","G153094A","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG002":["S238L"],"OPG089":["E109K"],"OPG180":["D135N"]},"labels":{"aa":"OPG002: S238L; OPG089: E109K; OPG180: D135N"}}},{"name":"OR449682","node_attrs":{"div":63,"accession":"OR449682","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI968"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OR449682/2022-06-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"NODE_0000118","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","C179181-","C179190-","C186220T","T196308C"],"OPG001_dup":["L225S"],"OPG210":["A1622V"]},"labels":{"aa":"OPG001_dup: L225S; OPG210: A1622V"}},"children":[{"name":"ON929062","node_attrs":{"div":64,"accession":"ON929062","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI104"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/ON929062/2022-07-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{}}},{"name":"OP615338","node_attrs":{"div":66,"accession":"OP615338","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI459"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP615338/2022-09-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["G89716A","G128858A","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG110":["E29K"]},"labels":{"aa":"OPG110: E29K"}}}]},{"name":"NODE_0000119","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["G902A","C68981T","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG001":["S225L"],"OPG087":["S42L"]},"labels":{"aa":"OPG001: S225L; OPG087: S42L"}},"children":[{"name":"OP628437","node_attrs":{"div":67,"accession":"OP628437","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-080247/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP628437/2022-08-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["-607T","G94092A","G172483A","C185731T","-196615A"],"OPG113":["D788N"],"OPG200":["A112T"],"OPG210":["S1459L"]},"labels":{"aa":"OPG113: D788N; OPG200: A112T; OPG210: S1459L"}}},{"name":"OR030928","node_attrs":{"div":64,"accession":"OR030928","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_17"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR030928/2022-07-19"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-19"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}}]},{"name":"NODE_0000120","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["C80545T","G102614A","C170573T","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196308C"],"OPG001_dup":["L225S"],"OPG103":["S182L"],"OPG122":["V63I"],"OPG198":["S179L"]},"labels":{"aa":"OPG001_dup: L225S; OPG103: S182L; OPG122: V63I; OPG198: S179L"}},"children":[{"name":"OR035714","node_attrs":{"div":66,"accession":"OR035714","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_108"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR035714/2022-10-28"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["T196712-","A196713-","T196714-"]}}},{"name":"OR086994","node_attrs":{"div":66,"accession":"OR086994","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_185/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR086994/2022-08-03"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-03"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000121","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C89906T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG110":["S92F"]},"labels":{"aa":"OPG110: S92F"}},"children":[{"name":"OQ696098","node_attrs":{"div":68,"accession":"OQ696098","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain":{"value":"ANT-LDSP-ANT-MPX-30513C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OQ696098/2022-11-10"},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-11-10"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","G32863A","G45416A","C67823T","C72770T","C123118T","C148771T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG085":["E237K"],"OPG092":["E60K"],"OPG174":["D209N"]},"labels":{"aa":"OPG085: E237K; OPG092: E60K; OPG174: D209N"}}},{"name":"NODE_0000122","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["G94798A"],"OPG115":["E47K"]},"labels":{"aa":"OPG115: E47K","clade":"B.1.10"}},"children":[{"name":"ON720848","node_attrs":{"div":64,"accession":"ON720848","author":{"author":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"strain":{"value":"MpxV/Spain/MD-HGUGM-6513479/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Spain/ON720848/2022-05-27"},"country":{"value":"Spain"},"institution":{"value":"Microbial Genomics, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"},"date":{"value":"2022-05-27"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["A327-","T605-","T606-","A1697-","T4296-","T6587-","T6588-","T7253-","G7724-","T8017-","A8036-","T8499-","T9514-","A9869-","T10502-","A10914-","T11188-","C11749-","T11761-","T12121-","A15754-","A17087-","T18866-","A19360-","T20663-","A21081-","T21975-","T24678-","T25853-","T26099-","C27002-","A27114-","C27799-","A28529-","A28530-","T32194-","T33414-","G35949-","T37982-","T39131-","T39866-","T41744-","T42990-","C43014-","G43200-","A43443-","T44120-","T44738-","G46762-","T48675-","A49134-","G49833-","A51022-","A52765-","A54968-","A55124-","T55560-","T56040-","T57075-","A57277-","A58650-","T61749-","A62041-","T63628-","A64728-","A64935-","A65535-","A65967-","T66783-","A66843-","A67164-","C68466-","T68481-","C68899-","G69145-","A69744-","T69768-","A71254-","G71359-","T75833-","A76072-","T76084-","T76085-","A76153-","A76154-","A76890-","A77260-","T77803-","T78062-","A79042-","A79181-","G79217-","C79533T","A79787-","G80950-","C82482-","T84846-","T88095-","T88836-","T88941-","A89106-","T90646-","T91129-","T91370-","A91583-","A91705-","T94795-","A95341-","A95574-","G95742-","G95818-","A97351-","A97480-","A97501-","A97699-","A98683-","T101452-","G101515-","T102437-","T103367-","T103368-","T104279-","T105360-","T106596-","T108598-","A113921-","T113951-","C114431-","T114518-","T114755-","T115127-","G115801-","A116014-","C116494-","T116963-","T121121-","T121122-","G121269-","C121546-","T124022-","T124751-","A125249-","A126568-","T126682-","A126715-","A127250-","A127754-","A132023-","A132024-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133639-","T136780-","T137886-","A143045-","G143363-","T143478-","A144230-","T146131-","A148000-","A149727-","A150340-","T150538-","T150539-","A150635-","T150864-","A151490-","A151508-","G151545-","A152676-","T152686-","A153358-","A153424-","A153517-","T154862-","T155424-","C156607-","C156608-","A157997-","T163498-","T163597-","A163957-","A165461-","A166740-","G167640-","A167967-","T168120-","A170728-","T170758-","T170903-","T170904-","T172087-","T172667-","G179036-","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A179551-","A179950-","T180905-","G181052-","A181253-","C183534-","A183780-","T187080-","A190935-","A191015-","G191519-","A196613-","A196614-","T196888-","T197183-"],"OPG015_dup":["G156-"],"OPG016":["T176-"],"OPG019":["G49-"],"OPG021":["N95-"],"OPG023":["G385-"],"OPG043":["G53-"],"OPG044":["K147-"],"OPG066":["P223-"],"OPG068":["L159-","D545-"],"OPG070":["N145-"],"OPG074":["K523-"],"OPG084":["K3-","K272-","R416-"],"OPG085":["F457-"],"OPG087":["L15-","G97-"],"OPG090":["K26-"],"OPG096":["L83-"],"OPG098":["S121-"],"OPG099":["F47-"],"OPG100":["F19-"],"OPG102":["K33-"],"OPG104":["P24-"],"OPG109":["K206-"],"OPG111":["F128-"],"OPG112":["S42-"],"OPG115":["S46-"],"OPG116":["K72-"],"OPG117":["K435-","N478-","R551-"],"OPG118":["I80-"],"OPG122":["Y4-"],"OPG123":["K569-"],"OPG133":["K394-"],"OPG134":["E18-","P249-"],"OPG139":["P34-"],"OPG145":["F26-","F269-","K435-"],"OPG148":["I195-","F233-"],"OPG149":["K19-"],"OPG151":["K1034-"],"OPG164":["R90-"],"OPG165":["M239-"],"OPG172":["I192-"],"OPG175":["N96-"],"OPG176":["K178-"],"OPG178":["D13-"],"OPG180":["K223-","K276-"],"OPG181":["F151-"],"OPG189":["L56-","K209-"],"OPG190":["N114-"],"OPG192":["K4-"],"OPG193":["G103-","F263-"],"OPG198":["K231-"],"OPG208":["I96-"],"OPG209":["L130-"],"OPG210":["P727-"]},"labels":{"aa":"OPG015_dup: G156-; OPG016: T176-; OPG019: G49-; OPG021: N95-; OPG023: G385-; OPG043: G53-; OPG044: K147-; OPG066: P223-; OPG068: L159-, D545-; OPG070: N145-; OPG074: K523-; OPG084: K3-, K272-, R416-; OPG085: F457-; OPG087: L15-, G97-; OPG090: K26-; OPG096: L83-; OPG098: S121-; OPG099: F47-; OPG100: F19-; OPG102: K33-; OPG104: P24-; OPG109: K206-; OPG111: F128-; OPG112: S42-; OPG115: S46-; OPG116: K72-; OPG117: K435-, N478-, R551-; OPG118: I80-; OPG122: Y4-; OPG123: K569-; OPG133: K394-; OPG134: E18-, P249-; OPG139: P34-; OPG145: F26-, F269-, K435-; OPG148: I195-, F233-; OPG149: K19-; OPG151: K1034-; OPG164: R90-; OPG165: M239-; OPG172: I192-; OPG175: N96-; OPG176: K178-; OPG178: D13-; OPG180: K223-, K276-; OPG181: F151-; OPG189: L56-, K209-; OPG190: N114-; OPG192: K4-; OPG193: G103-, F263-; OPG198: K231-; OPG208: I96-; OPG209: L130-; OPG210: P727-"}}},{"name":"OP245334","node_attrs":{"div":65,"accession":"OP245334","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"MPX/PT0081/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP245334/2022-07-23"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-23"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["-607T","-609T","G610-","T611-","C120237T","G126047A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","A196619-","T196620-"],"OPG148":["R21K"]},"labels":{"aa":"OPG148: R21K"}}},{"name":"OP205110","node_attrs":{"div":63,"accession":"OP205110","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPXV_UK_2022_9000147"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP205110/2022-06-14"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-14"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP205091","node_attrs":{"div":63,"accession":"OP205091","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPXV_UK_2022_9000103"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP205091/2022-06-13"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-13"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP450985","node_attrs":{"div":63,"accession":"OP450985","author":{"author":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y.","value":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y."},"strain":{"value":"MPXV_USA_2022_TX0019"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP450985/2022-06-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["-607T","A136552-","T136553-","C136554-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP484683","node_attrs":{"div":65,"accession":"OP484683","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI362"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP484683/2022-09-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["C17027T","C84943T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-"],"OPG029":["D15N"],"OPG105":["S1273F"]},"labels":{"aa":"OPG029: D15N; OPG105: S1273F"}}},{"name":"OP894038","node_attrs":{"div":64,"accession":"OP894038","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI618"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP894038/2022-08-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["C33964T","T136514-","C136515-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","G181052-"],"OPG052":["R11Q"],"OPG153":["D385-"],"OPG209":["G179-"]},"labels":{"aa":"OPG052: R11Q; OPG153: D385-; OPG209: G179-"}}},{"name":"OQ773504","node_attrs":{"div":65,"accession":"OQ773504","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI885"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ773504/2022-07-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["C33103T","A41660-","A41661-","T41662-","T41663-","T41664-","G41665-","T41666-","T41667-","T41668-","T41669-","A41670-","C41671-","T41672-","C41673-","T41674-","A41675-","T41676-","A41677-","C45605T","G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG049":["E17K"],"OPG061":["Y70-","R71-","V72-","K73-","Q74-","I75-"]},"labels":{"aa":"OPG049: E17K; OPG061: Y70-, R71-, V72-, K73-, Q74-, I75-"}}},{"name":"OQ581847","node_attrs":{"div":76,"accession":"OQ581847","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0005b/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Spain/OQ581847/2022-07-01"},"country":{"value":"Spain"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"date":{"value":"2022-07-01"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["A43453G","A66769C","T88735A","G90070A","C101656T","G104325A","C121681T","G127869A","G132490A","T133095A","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T139779C","G140866T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C151204T","T176743A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG063":["L79P"],"OPG085":["V588G"],"OPG109":["E238V"],"OPG110":["D147N"],"OPG123":["A249V"],"OPG150":["G31R"],"OPG160":["S70Y"],"OPG205":["L363*"]},"labels":{"aa":"OPG063: L79P; OPG085: V588G; OPG109: E238V; OPG110: D147N; OPG123: A249V; OPG150: G31R; OPG160: S70Y; OPG205: L363*"}}},{"name":"OR264420","node_attrs":{"div":64,"accession":"OR264420","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain":{"value":"45_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Australia/OR264420/2022-07-10"},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-10"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["G63147A","-179218A","-179219T","-179220T"]}}},{"name":"NODE_0000123","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C150831T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-"]}},"children":[{"name":"ON959143","node_attrs":{"div":65,"accession":"ON959143","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O."},"strain":{"value":"MPX-96/Finland/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Finland/ON959143/2022-06-16"},"country":{"value":"Finland"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"date":{"value":"2022-06-16"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188491T"]}}},{"name":"OP382489","node_attrs":{"div":65,"accession":"OP382489","author":{"author":"Colson,P.","value":"Colson,P."},"strain":{"value":"hMPXV-IHU00012"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"France/OP382489/2022-07-19"},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-19"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["G109437A","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G150603-","A150604-","T150605-","A150606-","T150607-","G150608-","A150609-","T150610-","G150611-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG129":["S523L"],"OPG153":["D384-","D385-"]},"labels":{"aa":"OPG129: S523L; OPG153: D384-, D385-"}}},{"name":"OP879740","node_attrs":{"div":64,"accession":"OP879740","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"strain":{"value":"NJ-MPXV-022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP879740/2022-07-06"},"country":{"value":"USA"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"date":{"value":"2022-07-06"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-"]}}}]},{"name":"NODE_0000124","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["C20879T","C60094T"],"OPG036":["M62I"],"OPG080":["R642K"]},"labels":{"aa":"OPG036: M62I; OPG080: R642K"}},"children":[{"name":"OP415264","node_attrs":{"div":66,"accession":"OP415264","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPX_Tga3e9_9000325"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP415264/2022-08-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["G86904A","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035722","node_attrs":{"div":66,"accession":"OR035722","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_116"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR035722/2022-10-28"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G149818A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG176":["D4N"]},"labels":{"aa":"OPG176: D4N"}}},{"name":"OR464215","node_attrs":{"div":65,"accession":"OR464215","author":{"author":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y.","value":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y."},"strain":{"value":"MPXV_USA_2022_DC0006"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR464215/2022-08-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-"]}}}]},{"name":"NODE_0000125","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["G50672A"],"OPG070":["R28K"]},"labels":{"aa":"OPG070: R28K"}},"children":[{"name":"OP689664","node_attrs":{"div":66,"accession":"OP689664","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI511"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP689664/2022-10-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["C13624T","C43472T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG063":["E73K"]},"labels":{"aa":"OPG063: E73K"}}},{"name":"OP642412","node_attrs":{"div":64,"accession":"OP642412","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain":{"value":"ANT-LDSP-ANT-MPX-25340L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"strain_display":{"value":"Colombia/OP642412/2022-09-13"},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-09-13"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-"]}}},{"name":"NODE_0000126","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["C49265T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP536764","node_attrs":{"div":66,"accession":"OP536764","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"9000385"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP536764/2022-09-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["T606-","C100007T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"],"OPG118":["S521F"]},"labels":{"aa":"OPG118: S521F"}}},{"name":"OP459218","node_attrs":{"div":65,"accession":"OP459218","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain":{"value":"ANT-LDSP-ANT-MPX-23655-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP459218/2022-08-30"},"country":{"value":"Colombia"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"date":{"value":"2022-08-30"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP819958","node_attrs":{"div":65,"accession":"OP819958","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"strain":{"value":"QUI_INS_MPX_0967_L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP819958/2022-10-15"},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-10-15"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["G150603-","A150604-","T150605-","A150606-","T150607-","G150608-","A150609-","T150610-","G150611-"]}}}]}]}]}]},{"name":"NODE_0000135","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G1302A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C182950T"],"OPG001":["L92F"],"OPG210":["S532L"]},"labels":{"aa":"OPG001: L92F; OPG210: S532L","clade":"B.1.12"}},"children":[{"name":"OQ773485","node_attrs":{"div":62,"accession":"OQ773485","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI866"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ773485/2022-07-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150563-","T150564-","G150565-","A150566-","T150567-","-150590G","-150593G","-150594G","-150599G","-150602G","-179189A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"]}}},{"name":"NODE_0000136","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G78328A","C195908T"],"OPG001_dup":["L92F"]},"labels":{"aa":"OPG001_dup: L92F"}},"children":[{"name":"OP524001","node_attrs":{"div":63,"accession":"OP524001","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI399"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP524001/2022-09-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["-150590G","-150593G","-150594G","-150599G","-150602G"]}}},{"name":"NODE_0000137","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["C57550T","A150586-","T150587-","A150588-","T150589-","A150591-","T150592-","A150595-","T150596-","A150597-","T150598-","A150600-","T150601-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP415207","node_attrs":{"div":64,"accession":"OP415207","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPX_BhVKjm_9000233"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP415207/2022-07-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{}}},{"name":"OP415206","node_attrs":{"div":64,"accession":"OP415206","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPX_BhVKjm_9000232"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP415206/2022-07-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000138","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["A1302G","G111084A","A150586-","T150587-","A150588-","T150589-","A150591-","T150592-","A150595-","T150596-","A150597-","T150598-","A150600-","T150601-"],"OPG001":["F92L"]},"labels":{"aa":"OPG001: F92L"}},"children":[{"name":"OP013003","node_attrs":{"div":63,"accession":"OP013003","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I."},"strain":{"value":"MpxV/human/CAN/UN-NML-3276/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OP013003/2022-05-31"},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-31"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{}}},{"name":"ON880548","node_attrs":{"div":63,"accession":"ON880548","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"strain":{"value":"MpxV/human/CAN/UN-NML-3448/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/ON880548/2022-06-03"},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-03"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000139","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G121510A"]}},"children":[{"name":"ON880540","node_attrs":{"div":64,"accession":"ON880540","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"strain":{"value":"MpxV/human/CAN/UN-NML-3342/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/ON880540/2022-06-01"},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-01"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{}}},{"name":"OR759170","node_attrs":{"div":69,"accession":"OR759170","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain":{"value":"hMpxV/Canada/ON-PHOL082/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OR759170/2022-08-01"},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["-607T","G10060A","G37022A","C132410T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G154793A","C180055T","-196615A"],"OPG055":["S21F"],"OPG181":["D128N"]},"labels":{"aa":"OPG055: S21F; OPG181: D128N"}}}]},{"name":"NODE_0000140","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G98233A","G98455A","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG117":["D729N"],"OPG118":["G4K"]},"labels":{"aa":"OPG117: D729N; OPG118: G4K"}},"children":[{"name":"ON880413","node_attrs":{"div":66,"accession":"ON880413","author":{"author":"Coletti,T.M.,Ghilardi,F.,khan,M.J.,Claro,I.M.,Valenca,I.N.,Faria,N.R.,Sabino,E.C.","value":"Coletti,T.M.,Ghilardi,F.,khan,M.J.,Claro,I.M.,Valenca,I.N.,Faria,N.R.,Sabino,E.C."},"strain":{"value":"MPX/BR0002/2022"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Brazil/ON880413/2022-06-14"},"country":{"value":"Brazil"},"institution":{"value":"Imperial College London, School of Public Health"},"date":{"value":"2022-06-14"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["C76334T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG097":["R181K"]},"labels":{"aa":"OPG097: R181K"}}},{"name":"NODE_0000141","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G98456A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T"]}},"children":[{"name":"OP270022","node_attrs":{"div":69,"accession":"OP270022","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"strain":{"value":"MpxV/human/CAN/UN-NML-3972/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OP270022/2022-07-04"},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-07-04"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","G3361A","C152970T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G181349A","C193849T"],"OPG003":["S416L"],"OPG003_dup":["S416L"]},"labels":{"aa":"OPG003: S416L; OPG003_dup: S416L"}}},{"name":"OP185711","node_attrs":{"div":66,"accession":"OP185711","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_NY0006"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP185711/2022-06-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR209324","node_attrs":{"div":68,"accession":"OR209324","author":{"author":"Li,C.M.","value":"Li,C.M."},"strain":{"value":"MPXV_USA_2022_NE0004"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR209324/2022-07-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["-607T","C10484T","A61974G","C179199-","A179200-","T179201-","T179202-","A179221-","T179222-","A179223-","T179224-","A179225-","-196615A"]}}},{"name":"OR209309","node_attrs":{"div":69,"accession":"OR209309","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_TN0019"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR209309/2022-12-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-12-XX"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["C93601T","C94418T","T133101-","T133102-","C136029T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["A624V"],"OPG114":["E84K"]},"labels":{"aa":"OPG113: A624V; OPG114: E84K"}}},{"name":"OR464205","node_attrs":{"div":68,"accession":"OR464205","author":{"author":"Gigante,C.,Xia,D.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y.","value":"Gigante,C.,Xia,D.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y."},"strain":{"value":"MPXV_USA_2022_PA0003"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR464205/2022-08-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["-607T","C30930T","T67849G","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179221-","T179222-","A179223-","T179224-","A179225-","-196615A"],"OPG047":["D89N"],"OPG085":["N228T"]},"labels":{"aa":"OPG047: D89N; OPG085: N228T"}}},{"name":"NODE_0000142","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G153910A","C179172-","A179173-","T179174-","T179175-","C179199-","A179200-","T179201-","T179202-","A179221-","T179222-","A179223-","T179224-","A179225-"],"OPG180":["E407K"]},"labels":{"aa":"OPG180: E407K"}},"children":[{"name":"OQ427114","node_attrs":{"div":68,"accession":"OQ427114","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_NY0039"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ427114/2022-10-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G71407A","-179172C","-179173A","-179174T","-179175T","-196615A"],"OPG091":["R13K"]},"labels":{"aa":"OPG091: R13K"}}},{"name":"OR026631","node_attrs":{"div":69,"accession":"OR026631","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200369/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR026631/2022-09-06"},"country":{"value":"USA"},"institution":{"value":"Utah Public Health Laboratory, Utah Public Health Laboratory Infectious Disease submission group"},"date":{"value":"2022-09-06"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G11924A","A37326C"],"OPG023":["S326L"],"OPG056":["I570R"]},"labels":{"aa":"OPG023: S326L; OPG056: I570R"}}},{"name":"OQ918701","node_attrs":{"div":72,"accession":"OQ918701","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00490/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ918701/2023-02-10"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-02-10"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["C21910T","G28483A","G39552A","A57421-","C57422-","A57423-","A57424-","A57425-","A57426-","A57427-","G57428-","G57429-","A57430-","C57431-","A57432-","T57433-","G57434-","T57435-","A57436-","A57437-","A57438-","C57439-","T57440-","T57441-","G132490A","C150443T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG037":["R175K"],"OPG057":["S215F"],"OPG075":["K20-","F21-","T22-","C23-","P24-","F25-","C26-"],"OPG176":["T212I"]},"labels":{"aa":"OPG037: R175K; OPG057: S215F; OPG075: K20-, F21-, T22-, C23-, P24-, F25-, C26-; OPG176: T212I"}}},{"name":"OR759180","node_attrs":{"div":71,"accession":"OR759180","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain":{"value":"hMpxV/Canada/ON-PHOL092/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OR759180/2022-09-01"},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["T606-","C16209T","C24208T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","G182088A","G182189A","A196614-"],"OPG027":["E57K"],"OPG210":["E245K"]},"labels":{"aa":"OPG027: E57K; OPG210: E245K"}}}]},{"name":"NODE_0000143","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["C24231T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T"]}},"children":[{"name":"OP390179","node_attrs":{"div":67,"accession":"OP390179","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"strain":{"value":"BOL-UNIMOL-MPX-293015-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP390179/2022-08-24"},"country":{"value":"Colombia"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"date":{"value":"2022-08-24"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP382485","node_attrs":{"div":68,"accession":"OP382485","author":{"author":"Colson,P.","value":"Colson,P."},"strain":{"value":"hMPXV-IHU00008"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"France/OP382485/2022-07-05"},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G184227A"],"OPG210":["D958N"]},"labels":{"aa":"OPG210: D958N"}}},{"name":"OR095033","node_attrs":{"div":68,"accession":"OR095033","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_215/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR095033/2022-08-08"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-08"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G61102A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG080":["S306F"]},"labels":{"aa":"OPG080: S306F"}}},{"name":"NODE_0000144","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G23457A"],"OPG039":["S221F"]},"labels":{"aa":"OPG039: S221F"}},"children":[{"name":"OP415236","node_attrs":{"div":68,"accession":"OP415236","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPX_ilzdZn_9000269"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP415236/2022-08-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["A190409-","A190410-","T190411-","G190412-","G190413-","A190414-","T190415-","T190416-","C190417-","G190418-","C190419-","G190420-","T190421-","A190422-","T190423-","A190424-","G190425-","C190426-"]}}},{"name":"OR264365","node_attrs":{"div":68,"accession":"OR264365","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain":{"value":"12_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Australia/OR264365/2022-07-18"},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-18"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{}}}]}]}]}]}]}]},{"name":"NODE_0000145","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["C70780T","-150590G","-150593G","-150594G","-150599G","-150602G"]},"labels":{"clade":"B.1.5"}},"children":[{"name":"OP150925","node_attrs":{"div":62,"accession":"OP150925","author":{"author":"Gigante,C.,Xia,D.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y.","value":"Gigante,C.,Xia,D.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y."},"strain":{"value":"MPXV_USA_2022_GA001"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP150925/2022-05-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON918656","node_attrs":{"div":66,"accession":"ON918656","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"strain":{"value":"MPXV/human/Taiwan/110-231642/2022"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Taiwan/ON918656/2022-06-XX"},"country":{"value":"Taiwan"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["C28702T","T34793C","T50861C","C51777T","G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG054":["T402A"],"OPG070":["V91A"],"OPG071":["E888K"]},"labels":{"aa":"OPG054: T402A; OPG070: V91A; OPG071: E888K"}}},{"name":"ON843165","node_attrs":{"div":62,"accession":"ON843165","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0033/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/ON843165/2022-05-24"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-05-24"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}}},{"name":"ON780017","node_attrs":{"div":62,"accession":"ON780017","author":{"author":"Gramigna,G.,Giombini,E.,Gruber,C.E.M.,Rueca,M.,Carletti,F.,Cicalini,S.,Lapa,D.,Puro,V.,Marani,A.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Rivano Capparuccia,M.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F.","value":"Gramigna,G.,Giombini,E.,Gruber,C.E.M.,Rueca,M.,Carletti,F.,Cicalini,S.,Lapa,D.,Puro,V.,Marani,A.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Rivano Capparuccia,M.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F."},"strain":{"value":"INMI-Pt4"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Italy/ON780017/2022-05-21"},"country":{"value":"Italy"},"institution":{"value":"INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology"},"date":{"value":"2022-05-21"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A"]}}},{"name":"OP245318","node_attrs":{"div":66,"accession":"OP245318","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"MPX/PT0064/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP245318/2022-08-01"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["G71227A","C133867T","C134247T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G158866A"],"OPG090":["E17K"]},"labels":{"aa":"OPG090: E17K"}}},{"name":"OP414288","node_attrs":{"div":62,"accession":"OP414288","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0244/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP414288/2022-06-21"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-06-21"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","-196615A"]}}},{"name":"OP355582","node_attrs":{"div":63,"accession":"OP355582","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI327"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP355582/2022-08-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["G6619A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","A188351-"]}}},{"name":"OP555486","node_attrs":{"div":62,"accession":"OP555486","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0390/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555486/2022-07-11"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-11"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","-179175T","T179244-","C179245-","G179246-","T179247-"]}}},{"name":"OP536756","node_attrs":{"div":64,"accession":"OP536756","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"9000376"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP536756/2022-08-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["C69888T","C150392T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG089":["S8L"],"OPG176":["S195F"]},"labels":{"aa":"OPG089: S8L; OPG176: S195F"}}},{"name":"OP523979","node_attrs":{"div":63,"accession":"OP523979","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI377"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP523979/2022-09-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G174625A"],"OPG204":["E32K"]},"labels":{"aa":"OPG204: E32K"}}},{"name":"OP555650","node_attrs":{"div":64,"accession":"OP555650","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0579/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555650/2022-09-10"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-10"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["C41022T","A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G159001A"],"OPG060":["R54K"],"OPG153":["D385-"],"OPG185":["D29N"]},"labels":{"aa":"OPG060: R54K; OPG153: D385-; OPG185: D29N"}}},{"name":"OP783902","node_attrs":{"div":62,"accession":"OP783902","author":{"author":"Laubscher,F.,Marques-Melancia,S.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Marques-Melancia,S.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A."},"strain":{"value":"hMPXV-CH-38347314/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Switzerland/OP783902/2022-06-08"},"country":{"value":"Switzerland"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"date":{"value":"2022-06-08"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ274883","node_attrs":{"div":62,"accession":"OQ274883","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI664"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ274883/2022-05-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","A152676-","T152686-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OR449686","node_attrs":{"div":63,"accession":"OR449686","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI972"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OR449686/2022-06-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["G133806A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"ON959175","node_attrs":{"div":62,"accession":"ON959175","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI162"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/ON959175/2022-07-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}}},{"name":"OP626123","node_attrs":{"div":62,"accession":"OP626123","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI485"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP626123/2022-07-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}}},{"name":"NODE_0000147","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["C30283T","C37054T","G150590-","G150593-","G150594-","G150599-","G150602-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","G179589A","G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N"}},"children":[{"name":"OR264398","node_attrs":{"div":66,"accession":"OR264398","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain":{"value":"34_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Australia/OR264398/2022-06-30"},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-06-30"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{}}},{"name":"OR264397","node_attrs":{"div":66,"accession":"OR264397","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain":{"value":"34_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Australia/OR264397/2022-08-16"},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-16"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["T606-"]}}}]},{"name":"NODE_0000148","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["C44333T","G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG064":["M522I"]},"labels":{"aa":"OPG064: M522I"}},"children":[{"name":"OP415189","node_attrs":{"div":63,"accession":"OP415189","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPX_luLfgA_9000208"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP415189/2022-07-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{}}},{"name":"OP358276","node_attrs":{"div":67,"accession":"OP358276","author":{"author":"Tramuto,F.","value":"Tramuto,F."},"strain":{"value":"SIC-AOUP-UNIPA_VL_9aug"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Italy/OP358276/2022-08-09"},"country":{"value":"Italy"},"institution":{"value":"University of Palermo, Department of Health Promotion Sciences Maternal and Infant Care, Internal Medicine and Medical Specialties \"G. D'Alessandro\"\"\""},"date":{"value":"2022-08-09"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["C33103T","G93512T","C114490T","C133295T","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-"],"OPG049":["E17K"],"OPG113":["K594N"],"OPG133":["D403N"]},"labels":{"aa":"OPG049: E17K; OPG113: K594N; OPG133: D403N"}}},{"name":"OR035702","node_attrs":{"div":67,"accession":"OR035702","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_96"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR035702/2022-05-30"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-05-30"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["C29315T","C60396T","G149807A","C161572T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG046":["D139N"]},"labels":{"aa":"OPG046: D139N"}}},{"name":"OR035675","node_attrs":{"div":64,"accession":"OR035675","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_69"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR035675/2022-06-30"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-06-30"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["G161488A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}}]},{"name":"NODE_0000149","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","C160426T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A"]}},"children":[{"name":"OQ503755","node_attrs":{"div":68,"accession":"OQ503755","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-113327/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ503755/2022-11-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-11-XX"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["T10449-","A10450-","G10451-","A10452-","T10453-","G75332A","T124690C","C135762T","C144211T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G185394A"],"OPG095":["R177K"],"OPG210":["E1347K"]},"labels":{"aa":"OPG095: R177K; OPG210: E1347K"}}},{"name":"NODE_0000150","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["G111379A","G165326A"],"OPG130":["S175L"],"OPG190":["E69K"]},"labels":{"aa":"OPG130: S175L; OPG190: E69K"}},"children":[{"name":"OP351284","node_attrs":{"div":67,"accession":"OP351284","author":{"author":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T.","value":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T."},"strain":{"value":"MPXV22/human/USA-OK-69"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP351284/2022-07-22"},"country":{"value":"USA"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"date":{"value":"2022-07-22"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G22207A","C120671T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616T","-196617A"],"OPG037":["S76F"]},"labels":{"aa":"OPG037: S76F"}}},{"name":"OP303796","node_attrs":{"div":65,"accession":"OP303796","author":{"author":"Gigante,C.M.,Hughes,S.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_NY0015"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP303796/2022-06-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-"]}}},{"name":"OQ320464","node_attrs":{"div":65,"accession":"OQ320464","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_NY0025"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ320464/2022-08-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{}}},{"name":"OQ721933","node_attrs":{"div":66,"accession":"OQ721933","author":{"author":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y.","value":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y."},"strain":{"value":"MPXV_USA_2022_OH0005"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ721933/2022-09-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["G48045A","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","G173318-","G173319-","G173320-","C173321-","A173322-","A173323-","A173324-","A173325-","C173326-","A173327-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"]}}}]}]}]},{"name":"NODE_0000151","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N","clade":"B.1.2"}},"children":[{"name":"ON959156","node_attrs":{"div":64,"accession":"ON959156","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI141"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/ON959156/2022-07-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["C23845T","G118391A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG039":["D92N"]},"labels":{"aa":"OPG039: D92N"}}},{"name":"ON929079","node_attrs":{"div":62,"accession":"ON929079","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI124"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/ON929079/2022-07-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP205082","node_attrs":{"div":63,"accession":"OP205082","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPXV_UK_2022_9000079"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP205082/2022-06-15"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-15"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["C123899T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG144":["D12N"]},"labels":{"aa":"OPG144: D12N"}}},{"name":"OP415208","node_attrs":{"div":67,"accession":"OP415208","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPX_Fap1fz_9000234"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP415208/2022-07-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["T606-","C24282T","G24622A","C49694T","C92375T","G94221A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG040":["S286L"],"OPG113":["E831K"]},"labels":{"aa":"OPG040: S286L; OPG113: E831K"}}},{"name":"OP523982","node_attrs":{"div":62,"accession":"OP523982","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI380"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP523982/2022-09-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP580151","node_attrs":{"div":65,"accession":"OP580151","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"strain":{"value":"MPXV/Human/USA/CA-CDPH-MPX000002/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP580151/2022-06-02"},"country":{"value":"USA"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2022-06-02"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["C43068T","C75090T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C177626T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP879768","node_attrs":{"div":62,"accession":"OP879768","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"strain":{"value":"NJ-MPXV-056"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP879768/2022-08-31"},"country":{"value":"USA"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"date":{"value":"2022-08-31"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ274892","node_attrs":{"div":62,"accession":"OQ274892","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI673"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ274892/2022-05-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-"]}}},{"name":"OP150927","node_attrs":{"div":62,"accession":"OP150927","author":{"author":"Gigante,C.,Pavlick,J.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y.","value":"Gigante,C.,Pavlick,J.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y."},"strain":{"value":"MPXV_USA_2022_WA001"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP150927/2022-05-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP837346","node_attrs":{"div":62,"accession":"OP837346","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI584"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP837346/2022-06-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000153","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["C20992T","G143789A"],"OPG036":["D25N"],"OPG165":["D92N"]},"labels":{"aa":"OPG036: D25N; OPG165: D92N"}},"children":[{"name":"NODE_0000154","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["C147168T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG171":["L61F"]},"labels":{"aa":"OPG171: L61F"}},"children":[{"name":"OP279039","node_attrs":{"div":65,"accession":"OP279039","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"strain":{"value":"MpxV/human/CAN/UN-NML-4117/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OP279039/2022-06-28"},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-28"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OR264414","node_attrs":{"div":65,"accession":"OR264414","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain":{"value":"42_C"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Australia/OR264414/2022-06-22"},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-06-22"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000155","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["C29229T","C57492T","G73939A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG045":["D12N"],"OPG075":["E3K"],"OPG094":["D54N"]},"labels":{"aa":"OPG045: D12N; OPG075: E3K; OPG094: D54N"}},"children":[{"name":"OP536807","node_attrs":{"div":70,"accession":"OP536807","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"9000438"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP536807/2022-09-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G10475A","G23462A","C171808T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG199":["S274L"]},"labels":{"aa":"OPG199: S274L"}}},{"name":"OP555593","node_attrs":{"div":68,"accession":"OP555593","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0522/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555593/2022-08-18"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-18"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["A12397-","T12398-","C12399-","C12400-","T12401-","C12402-","G29535A"],"OPG023":["E167-","D168-"]},"labels":{"aa":"OPG023: E167-, D168-"}}}]}]},{"name":"NODE_0000156","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188391T"]}},"children":[{"name":"OP205083","node_attrs":{"div":63,"accession":"OP205083","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPXV_UK_2022_9000092"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP205083/2022-05-25"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-05-25"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T"]}}},{"name":"OP415232","node_attrs":{"div":64,"accession":"OP415232","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPX_AZQnFn_9000263"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP415232/2022-08-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","C188491T"]}}},{"name":"OP605583","node_attrs":{"div":68,"accession":"OP605583","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain":{"value":"Slovenia-MPXV-42-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Slovenia/OP605583/2022-08-XX"},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["A161-","-607T","C17614A","C27187T","G111484A","G147305A","C159401A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T"],"OPG030":["V74L"],"OPG043":["D257N"],"OPG130":["T140I"],"OPG185":["S162Y"]},"labels":{"aa":"OPG030: V74L; OPG043: D257N; OPG130: T140I; OPG185: S162Y"}}},{"name":"OP881946","node_attrs":{"div":67,"accession":"OP881946","author":{"author":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y.","value":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y."},"strain":{"value":"MPXV_USA_2022_FL0027"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP881946/2022-09-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G65961A","G126646A","C168226T","C179190-","A179191-","T179192-","T179193-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C188998T"],"OPG084":["E414K"],"OPG148":["E221K"]},"labels":{"aa":"OPG084: E414K; OPG148: E221K"}}},{"name":"OQ427123","node_attrs":{"div":65,"accession":"OQ427123","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_TN0015"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ427123/2022-10-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-607T","G170311A","T170904-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","C180606T","-196615A"],"OPG198":["E92K"],"OPG209":["S30L"]},"labels":{"aa":"OPG198: E92K; OPG209: S30L"}}},{"name":"OR086973","node_attrs":{"div":64,"accession":"OR086973","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_164/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR086973/2022-07-27"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-27"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G135633A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T"]}}},{"name":"NODE_0000157","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T157527C","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}},"children":[{"name":"OP555483","node_attrs":{"div":65,"accession":"OP555483","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0387/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555483/2022-07-12"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-12"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G154098A"]}}},{"name":"OQ417831","node_attrs":{"div":68,"accession":"OQ417831","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI698"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ417831/2022-08-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["C11749-","G25842A","G54848A","G143708A","G150551-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","T150567-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G187507A"],"OPG042":["P419L"],"OPG165":["E65K"]},"labels":{"aa":"OPG042: P419L; OPG165: E65K"}}}]},{"name":"NODE_0000158","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["T26669C","G96073A","G115235A","C125294T","C135868T"],"OPG117":["D9N"]},"labels":{"aa":"OPG117: D9N"}},"children":[{"name":"OQ159027","node_attrs":{"div":69,"accession":"OQ159027","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI632"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ159027/2022-11-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-11-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G77052A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP959061","node_attrs":{"div":68,"accession":"OP959061","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"strain":{"value":"BOL-UNIMOL-MPX-293613-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP959061/2022-10-11"},"country":{"value":"Colombia"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"date":{"value":"2022-10-11"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T"]}}}]},{"name":"NODE_0000159","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["T606-","G45781A","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A196614-"],"OPG064":["H40Y"]},"labels":{"aa":"OPG064: H40Y"}},"children":[{"name":"OQ427133","node_attrs":{"div":67,"accession":"OQ427133","author":{"author":"Gigante,C.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y.","value":"Gigante,C.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_CA0016"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ427133/2022-11-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-11-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-606T","-607T","G33695A","G37974A","C157380T","C179190-","A179191-","T179192-","T179193-","-196614A","-196615A"],"OPG056":["S354L"]},"labels":{"aa":"OPG056: S354L"}}},{"name":"OQ557949","node_attrs":{"div":64,"accession":"OQ557949","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_NY0010"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ557949/2022-07-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"]}}}]},{"name":"NODE_0000160","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G2126A","C64132T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C154736T","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G183791A","C195084T"],"OPG002":["S209L"],"OPG002_dup":["S209L"],"OPG083":["M195I"],"OPG181":["P109S"]},"labels":{"aa":"OPG002: S209L; OPG002_dup: S209L; OPG083: M195I; OPG181: P109S"}},"children":[{"name":"OQ330996","node_attrs":{"div":68,"accession":"OQ330996","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00389/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ330996/2022-12-12"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-12-12"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["A764-","T765-","T766-","C162837T","T179244-"]}}},{"name":"OR178740","node_attrs":{"div":69,"accession":"OR178740","author":{"author":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J.","value":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J."},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000191/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR178740/2023-01-12"},"country":{"value":"USA"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2023-01-12"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G39327A","C110699T","C179145-"],"OPG057":["A290V"]},"labels":{"aa":"OPG057: A290V"}}}]},{"name":"NODE_0000161","node_attrs":{"div":69,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G8638A","C21548T","C47820T","C68218T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","C188236T","C188339T"],"OPG037":["D296N"],"OPG085":["R105Q"]},"labels":{"aa":"OPG037: D296N; OPG085: R105Q"}},"children":[{"name":"OQ979623","node_attrs":{"div":71,"accession":"OQ979623","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-048370/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ979623/2023-04-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-04-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["C70252T","C102741T"],"OPG122":["S105L"]},"labels":{"aa":"OPG122: S105L"}}},{"name":"NODE_0000162","node_attrs":{"div":71,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G12239A","G12488A"],"OPG023":["S138L","S221F"]},"labels":{"aa":"OPG023: S138L, S221F"}},"children":[{"name":"OQ979624","node_attrs":{"div":71,"accession":"OQ979624","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-028492/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ979624/2023-02-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-02-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-607T","-196615A"]}}},{"name":"OR427345","node_attrs":{"div":72,"accession":"OR427345","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-036395/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR427345/2023-03-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-03-XX"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G12748A"]}}}]}]}]}]},{"name":"NODE_0000163","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["G74360A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG094":["R194H"]},"labels":{"aa":"OPG094: R194H","clade":"B.1.1"}},"children":[{"name":"ON792321","node_attrs":{"div":62,"accession":"ON792321","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba6450e/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Switzerland/ON792321/2022-06-02"},"country":{"value":"Switzerland"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"date":{"value":"2022-06-02"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","A19360-","T19361-","C19362-","A19363-","T19364-","T19365-","A43653-","T43654-","T43655-","A49176-","A49177-","T49178-","T49179-","T49180-","T49181-","A49182-","T49183-","T49184-","A49185-","A49186-","C49187-","G49188-","G49189-","T49190-","A49191-","A49192-","T49193-","A79063-","A79064-","T79065-","T79066-","T79067-","T79068-","A79069-","A79070-","T79071-","A79072-","T79073-","A79074-","A79075-","T79076-","A79077-","C79078-","T79079-","T79080-","A79081-","A79082-","A79083-","A79084-","A79085-","T79086-","G79087-","G79088-","A79089-","T79090-","G79091-","T79092-","T79093-","G79094-","T79095-","G79096-","T79097-","C79098-","G79099-","T79100-","T79101-","A79102-","A152691-","A152692-","T152693-","G152694-","A152695-","C152696-","G152697-","T152698-","A175944-","T175945-","A175946-","T175947-","C175948-","A175949-","A175950-","C179127A","C179136T","T179138A","T179148-","T179157-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","C179190T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T180493-","A180494-","T180495-","C180496-","A180497-","T180498-","T180499-"],"OPG063":["D50-"],"OPG068":["N329-","G330-","N331-","T332-","F333-","I334-"],"OPG205":["I97-","S98-","I99-"]},"labels":{"aa":"OPG063: D50-; OPG068: N329-, G330-, N331-, T332-, F333-, I334-; OPG205: I97-, S98-, I99-"}}},{"name":"ON694329","node_attrs":{"div":62,"accession":"ON694329","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI025"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/ON694329/2022-05-XX"},"country":{"value":"Germany"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-","A192490-","A192491-","G192492-","T192493-","T192494-","A192495-","G192496-","T192497-","T192498-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP204857","node_attrs":{"div":64,"accession":"OP204857","author":{"author":"Rhie,G.-E.","value":"Rhie,G.-E."},"strain":{"value":"MPXV-ROK-P1-2022"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"South Korea/OP204857/2022-08-XX"},"country":{"value":"South Korea"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C786T","C71728T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G173429A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG091":["A120V"]},"labels":{"aa":"OPG091: A120V"}}},{"name":"OP382479","node_attrs":{"div":62,"accession":"OP382479","author":{"author":"Colson,P.","value":"Colson,P."},"strain":{"value":"hMPXV-IHU00002"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"France/OP382479/2022-07-01"},"country":{"value":"France"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-01"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP615337","node_attrs":{"div":65,"accession":"OP615337","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI453"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP615337/2022-09-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C92284T","C116142T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","G187135A"],"OPG113":["S185L"]},"labels":{"aa":"OPG113: S185L"}}},{"name":"OP555635","node_attrs":{"div":67,"accession":"OP555635","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0564/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555635/2022-09-05"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-05"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C23422T","G54619A","G68997A","C69705T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C156100T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"],"OPG039":["E233K"]},"labels":{"aa":"OPG039: E233K"}}},{"name":"OP837475","node_attrs":{"div":64,"accession":"OP837475","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"strain":{"value":"DC_INS_MPX_1009_L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Colombia/OP837475/2022-09-19"},"country":{"value":"Colombia"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-09-19"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C17764T","G54336A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG030":["D24N"],"OPG071":["P35S"]},"labels":{"aa":"OPG030: D24N; OPG071: P35S"}}},{"name":"OR449622","node_attrs":{"div":62,"accession":"OR449622","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI909"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OR449622/2022-06-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150562-","A150563-","T150564-","G150565-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"OR209328","node_attrs":{"div":64,"accession":"OR209328","author":{"author":"Li,C.M.","value":"Li,C.M."},"strain":{"value":"MPXV_USA_2022_OR0002"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR209328/2022-07-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C92819T","G136816A","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"]}}},{"name":"OR095036","node_attrs":{"div":65,"accession":"OR095036","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_218/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR095036/2022-08-08"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-08"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C25828T","G107496A","G109463A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG042":["E424K"]},"labels":{"aa":"OPG042: E424K"}}},{"name":"OR500079","node_attrs":{"div":67,"accession":"OR500079","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"strain":{"value":"hMpxV/Romania/B-16/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Romania/OR500079/2022-08-04"},"country":{"value":"Romania"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"date":{"value":"2022-08-04"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["A31817T","C67289T","G97717T","C133109A","C166374G","T166375G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG085":["E415K"],"OPG117":["E557*"],"OPG191":["L72G"]},"labels":{"aa":"OPG085: E415K; OPG117: E557*; OPG191: L72G"}}},{"name":"OR500078","node_attrs":{"div":62,"accession":"OR500078","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"strain":{"value":"hMpxV/Romania/B-8/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Romania/OR500078/2022-06-29"},"country":{"value":"Romania"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"date":{"value":"2022-06-29"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["T92388-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["F220-"]},"labels":{"aa":"OPG113: F220-"}}},{"name":"NODE_0000164","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["-607T","G49677A","G52232A","G59218A","C119838T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG068":["E493K"],"OPG071":["S736L"],"OPG079":["S135L"]},"labels":{"aa":"OPG068: E493K; OPG071: S736L; OPG079: S135L"}},"children":[{"name":"OP310054","node_attrs":{"div":68,"accession":"OP310054","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-088213/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP310054/2022-08-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C69801A","C78362T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG088":["E21D"]},"labels":{"aa":"OPG088: E21D"}}},{"name":"OR427334","node_attrs":{"div":71,"accession":"OR427334","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-121247/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR427334/2022-12-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-12-XX"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C11810T","C63120T","G75522A","C159899T","G160110A"],"OPG023":["R364K"]},"labels":{"aa":"OPG023: R364K"}}}]},{"name":"NODE_0000165","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C11401T","A136552-","T136553-","C136554-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}},"children":[{"name":"OQ427112","node_attrs":{"div":65,"accession":"OQ427112","author":{"author":"Gigante,C.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y.","value":"Gigante,C.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y."},"strain":{"value":"MPXV_USA_2022_NV0005"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ427112/2022-10-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C72269T","T133102-","G140194A","G158318A","C179190-","A179191-","T179192-","T179193-"],"OPG092":["D227N"],"OPG159":["D143N"],"OPG160":["S294L"]},"labels":{"aa":"OPG092: D227N; OPG159: D143N; OPG160: S294L"}}},{"name":"OQ721942","node_attrs":{"div":65,"accession":"OQ721942","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"strain":{"value":"MPXV_USA_2022_TX0051"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ721942/2022-09-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["G23673A","G50121A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"],"OPG039":["S149L"],"OPG069":["E46K"]},"labels":{"aa":"OPG039: S149L; OPG069: E46K"}}}]},{"name":"NODE_0000166","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C29887T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}},"children":[{"name":"OR264437","node_attrs":{"div":63,"accession":"OR264437","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain":{"value":"56_C"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Australia/OR264437/2022-09-06"},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-09-06"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-"],"OPG044":["K147-"]},"labels":{"aa":"OPG044: K147-"}}},{"name":"OR264424","node_attrs":{"div":63,"accession":"OR264424","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain":{"value":"47_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Australia/OR264424/2022-07-13"},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-13"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000167","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["G118500A","G160406A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG136":["T363M"]},"labels":{"aa":"OPG136: T363M"}},"children":[{"name":"OR264402","node_attrs":{"div":64,"accession":"OR264402","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain":{"value":"38_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Australia/OR264402/2022-08-22"},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-22"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{}}},{"name":"OR264399","node_attrs":{"div":64,"accession":"OR264399","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain":{"value":"36_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Australia/OR264399/2022-06-30"},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-06-30"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","A43500-","T76084-","T76085-","T80846-","T80847-","A89106-","T121121-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","C196772-","A196773-","T196774-"],"OPG044":["K147-"]},"labels":{"aa":"OPG044: K147-"}}}]},{"name":"NODE_0000168","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C46672T","C56805T","C72314T","C103216T","C127628T","T152686-","-179194A","-179195T","-179196A","-179197T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C180857T"],"OPG066":["E253K"],"OPG074":["M107I"],"OPG092":["D212N"],"OPG123":["V619I"],"OPG149":["P145S"]},"labels":{"aa":"OPG066: E253K; OPG074: M107I; OPG092: D212N; OPG123: V619I; OPG149: P145S"}},"children":[{"name":"OR500081","node_attrs":{"div":69,"accession":"OR500081","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"strain":{"value":"hMpxV/Romania/B-35_L1/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Romania/OR500081/2023-01-05"},"country":{"value":"Romania"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"date":{"value":"2023-01-05"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C16327T","-179198A","-179199C","-179200A","-179201T"]}}},{"name":"OR500086","node_attrs":{"div":71,"accession":"OR500086","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"strain":{"value":"hMpxV/Romania/B-35_R3/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Romania/OR500086/2023-02-15"},"country":{"value":"Romania"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"date":{"value":"2023-02-15"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C42674T","G169748A","C179190T","T179192A","T179193A","-179198G","A185438C","C185439A"],"OPG063":["E339K"]},"labels":{"aa":"OPG063: E339K"}}}]},{"name":"NODE_0000169","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155698A"]}},"children":[{"name":"OR759194","node_attrs":{"div":72,"accession":"OR759194","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain":{"value":"hMpxV/Canada/ON-PHOL106/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OR759194/2022-07-01"},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-07-01"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C7235T","C32798T","C55589T","C61706T","G115768A","T120124-","T120125-","A120126-","G120127-","A120128-","T120129-","A120130-","A120131-","T120132-","G127806A","G159118A","G162726A","C177833T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"],"OPG074":["E513K"],"OPG080":["V105I"],"OPG134":["D7N"],"OPG137":["L175-","D176-","N177-"],"OPG150":["E10K"],"OPG185":["D68N"]},"labels":{"aa":"OPG074: E513K; OPG080: V105I; OPG134: D7N; OPG137: L175-, D176-, N177-; OPG150: E10K; OPG185: D68N"}}},{"name":"NODE_0000170","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["G161575A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OR459775","node_attrs":{"div":66,"accession":"OR459775","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain":{"value":"MPXV-ROK-P002-2022"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"South Korea/OR459775/2022-09-02"},"country":{"value":"South Korea"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2022-09-02"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["G14640A","C108843T","G136558C"],"OPG025":["H210Y"],"OPG153":["I370M"]},"labels":{"aa":"OPG025: H210Y; OPG153: I370M"}}},{"name":"OR086942","node_attrs":{"div":64,"accession":"OR086942","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_133/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR086942/2022-07-05"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["T133102-","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","A196748-","T196749-","C196750-"]}}}]}]},{"name":"NODE_0000171","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C22739T","-150590G","-150593G","-150594G","-150599G","-150602G","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"],"OPG038":["E141K"]},"labels":{"aa":"OPG038: E141K"}},"children":[{"name":"ON808413","node_attrs":{"div":63,"accession":"ON808413","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"strain":{"value":"CVR_MPXV1a"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/ON808413/2022-05-15"},"country":{"value":"United Kingdom"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"date":{"value":"2022-05-15"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-","G150590-","G150593-","G150594-","G150599-","G150602-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP205128","node_attrs":{"div":63,"accession":"OP205128","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPXV_UK_2022_9000179"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP205128/2022-06-26"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-26"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP415258","node_attrs":{"div":64,"accession":"OP415258","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPX_XAF7gk_9000317"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP415258/2022-08-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","C172730T","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP587245","node_attrs":{"div":65,"accession":"OP587245","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"strain":{"value":"MPXV/Human/USA/CA-CDPH-MPX000016/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP587245/2022-06-17"},"country":{"value":"USA"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2022-06-17"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C186124T","C189996T"],"OPG210":["S1590F"]},"labels":{"aa":"OPG210: S1590F"}}},{"name":"OP019276","node_attrs":{"div":63,"accession":"OP019276","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"strain":{"value":"hMPXV/Austria/MUW1527495/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Austria/OP019276/2022-06-21"},"country":{"value":"Austria"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"date":{"value":"2022-06-21"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON694339","node_attrs":{"div":63,"accession":"ON694339","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI016"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/ON694339/2022-05-XX"},"country":{"value":"Germany"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"NODE_0000173","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C22740T","C38937T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-"],"OPG056":["R33Q"]},"labels":{"aa":"OPG056: R33Q"}},"children":[{"name":"OP245321","node_attrs":{"div":65,"accession":"OP245321","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"MPX/PT0067/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP245321/2022-07-26"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-26"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["-607T","-609T","G610-","T611-"]}}},{"name":"OP555569","node_attrs":{"div":66,"accession":"OP555569","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0494/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555569/2022-08-15"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-15"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["T606-","C118523T","A196614-"]}}}]},{"name":"NODE_0000174","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["G150551-","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G173727A","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}},"children":[{"name":"OQ547771","node_attrs":{"div":64,"accession":"OQ547771","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI744"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ547771/2022-08-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["G181052-"],"OPG209":["G179-"]},"labels":{"aa":"OPG209: G179-"}}},{"name":"OR463746","node_attrs":{"div":64,"accession":"OR463746","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI795"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OR463746/2022-07-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["A181253-"]}}}]}]}]},{"name":"NODE_0000190","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C25644T"]},"labels":{"clade":"B.1.7"}},"children":[{"name":"OP205081","node_attrs":{"div":62,"accession":"OP205081","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPXV_UK_2022_9000078"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP205081/2022-06-14"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-14"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264370","node_attrs":{"div":64,"accession":"OR264370","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain":{"value":"18_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Australia/OR264370/2022-07-11"},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-11"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G144556A","C170573T","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}}},{"name":"ON843170","node_attrs":{"div":62,"accession":"ON843170","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0031/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/ON843170/2022-05-26"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-05-26"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OQ547747","node_attrs":{"div":62,"accession":"OQ547747","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI720"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ547747/2022-05-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G150551-","G150568-","A150569-","T150570-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OR759218","node_attrs":{"div":64,"accession":"OR759218","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain":{"value":"hMpxV/Canada/ON-PHOL130/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OR759218/2022-08-01"},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C81095T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C172410T"]}}},{"name":"NODE_0000087","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C66249T","C88644A","C104134T","C112638T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG109":["K268N"],"OPG123":["A313T"]},"labels":{"aa":"OPG109: K268N; OPG123: A313T"}},"children":[{"name":"OP263628","node_attrs":{"div":66,"accession":"OP263628","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI274"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP263628/2022-08-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{}}},{"name":"OP536778","node_attrs":{"div":68,"accession":"OP536778","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"9000400"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP536778/2022-09-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["T606-","G69081A","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G186489A","A196614-"],"OPG153":["D385-"],"OPG210":["D1712N"]},"labels":{"aa":"OPG153: D385-; OPG210: D1712N"}}}]},{"name":"NODE_0000128","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G98456A","C103258T","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG118":["G4E"],"OPG123":["D605N"]},"labels":{"aa":"OPG118: G4E; OPG123: D605N"}},"children":[{"name":"OP225965","node_attrs":{"div":64,"accession":"OP225965","author":{"author":"Gigante,C.M.,Lee,P.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y."},"strain":{"value":"MPXV_USA_2022_FL0012"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP225965/2022-06-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{}}},{"name":"OP879725","node_attrs":{"div":64,"accession":"OP879725","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"strain":{"value":"NJ-MPXV-004-rpt1"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP879725/2022-07-28"},"country":{"value":"USA"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"date":{"value":"2022-07-28"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-"]}}}]},{"name":"NODE_0000041","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G63147A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"]}},"children":[{"name":"ON918611","node_attrs":{"div":67,"accession":"ON918611","author":{"author":"Chan,W.Y.,Mtshali,S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J.","value":"Chan,W.Y.,Mtshali,S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J."},"strain":{"value":"NICD-SVPL223"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"South Africa/ON918611/2022-06-20"},"country":{"value":"South Africa"},"institution":{"value":"National Institute for Communicable Disease, Sequencing Core Facility"},"date":{"value":"2022-06-20"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["-607T","G10224A","G129761A","T143625A","C177847T"],"OPG021":["R213Q"],"OPG151":["D280N"],"OPG165":["I37N"],"OPG205":["S731L"]},"labels":{"aa":"OPG021: R213Q; OPG151: D280N; OPG165: I37N; OPG205: S731L"}}},{"name":"OP536792","node_attrs":{"div":66,"accession":"OP536792","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"9000418"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP536792/2022-08-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C15004T","C101845T","G177780A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196615-"],"OPG121":["S19F"],"OPG205":["E709K"]},"labels":{"aa":"OPG121: S19F; OPG205: E709K"}}},{"name":"OP523999","node_attrs":{"div":63,"accession":"OP523999","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI396"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP523999/2022-09-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}}]},{"name":"NODE_0000088","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C14077T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP205084","node_attrs":{"div":65,"accession":"OP205084","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPXV_UK_2022_9000093"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP205084/2022-05-30"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-05-30"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C4529T","G155585A","G192681A"],"OPG003":["D27N"],"OPG003_dup":["D27N"]},"labels":{"aa":"OPG003: D27N; OPG003_dup: D27N"}}},{"name":"OP415200","node_attrs":{"div":65,"accession":"OP415200","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPX_K1dQNt_9000224"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP415200/2022-07-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G126310A","G147799A"],"OPG148":["E109K"],"OPG172":["A125T"]},"labels":{"aa":"OPG148: E109K; OPG172: A125T"}}},{"name":"OP415186","node_attrs":{"div":63,"accession":"OP415186","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPX_cmjxZM_9000205"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP415186/2022-06-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000129","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G114316A","C148771T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG133":["H461Y"],"OPG174":["D209N"]},"labels":{"aa":"OPG133: H461Y; OPG174: D209N"}},"children":[{"name":"OR087006","node_attrs":{"div":68,"accession":"OR087006","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_197/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR087006/2022-08-03"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-03"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C12637T","G53377A","T133102-","C178569T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C182707T"],"OPG210":["S451F"]},"labels":{"aa":"OPG210: S451F"}}},{"name":"NODE_0000130","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G152437A"]}},"children":[{"name":"OQ159026","node_attrs":{"div":66,"accession":"OQ159026","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI631"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ159026/2022-10-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G150547A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","G187677A"]}}},{"name":"OQ627928","node_attrs":{"div":65,"accession":"OQ627928","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"strain":{"value":"INMI-19442022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Italy/OQ627928/2022-09-14"},"country":{"value":"Italy"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"date":{"value":"2022-09-14"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["-608T","G610-","T611-","A612-"]}}}]}]},{"name":"NODE_0000089","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G42504A","A196614-"]}},"children":[{"name":"OP204840","node_attrs":{"div":64,"accession":"OP204840","author":{"author":"Seang,S.,Burrel,S.,Todesco,E.,Leducq,V.,Monsel,G.,Le Pluart,D.,Cordevant,C.,Pourcher,V.,Palich,R.,Charpentier,C.","value":"Seang,S.,Burrel,S.,Todesco,E.,Leducq,V.,Monsel,G.,Le Pluart,D.,Cordevant,C.,Pourcher,V.,Palich,R.,Charpentier,C."},"strain":{"value":"PatientMPXV"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"France/OP204840/2022-06-10"},"country":{"value":"France"},"institution":{"value":"APHP Pitie Salpetriere SU, Virology"},"date":{"value":"2022-06-10"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G163250A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196612-","A196613-"]}}},{"name":"OP555558","node_attrs":{"div":65,"accession":"OP555558","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0479/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555558/2022-08-09"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-09"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["T606-","C134850T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C159741T"]}}},{"name":"NODE_0000090","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C5292T","G74267A","C115870T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A161784T","G191918A"],"OPG015":["D289N"],"OPG015_dup":["D289N"],"OPG094":["R163Q"]},"labels":{"aa":"OPG015: D289N; OPG015_dup: D289N; OPG094: R163Q"}},"children":[{"name":"OP324545","node_attrs":{"div":67,"accession":"OP324545","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0237/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP324545/2022-06-22"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-06-22"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{}}},{"name":"OP245331","node_attrs":{"div":68,"accession":"OP245331","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"MPX/PT0077/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP245331/2022-07-28"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-28"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G11924A"],"OPG023":["S326L"]},"labels":{"aa":"OPG023: S326L"}}}]}]},{"name":"NODE_0000131","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G120241A","T133098-","T133099-","T133100-","T133101-","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A"],"OPG137":["D214N"]},"labels":{"aa":"OPG137: D214N"}},"children":[{"name":"ON911481","node_attrs":{"div":66,"accession":"ON911481","author":{"author":"Galan-Huerta,K.A.,Paz-Infanzon,M.,Ruiz-Higareda,A.F.,Nuzzolo-Shihadeh,L.,Camacho-Ortiz,A.,Bocanegra-Ibarias,P.,Rivas-Estilla,A.M.,Zacarias-Villarreal,D.,Yamallel-Ortega,L.A.,Guerrero-Putz,M.D.,Ocampo-Candiani,J.","value":"Galan-Huerta,K.A.,Paz-Infanzon,M.,Ruiz-Higareda,A.F.,Nuzzolo-Shihadeh,L.,Camacho-Ortiz,A.,Bocanegra-Ibarias,P.,Rivas-Estilla,A.M.,Zacarias-Villarreal,D.,Yamallel-Ortega,L.A.,Guerrero-Putz,M.D.,Ocampo-Candiani,J."},"strain":{"value":"Monkeypox/MX-UANL001/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Mexico/ON911481/2022-06-28"},"country":{"value":"Mexico"},"institution":{"value":"Universidad Autonoma de Nuevo Leon - Facultad de Medicina, Centro de Investigacion e Innovacion en Virologia Medica"},"date":{"value":"2022-06-28"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["T606-","G57088A","C127530T","T168120C","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG074":["S13L"],"OPG149":["S112L"],"OPG193":["F263L"]},"labels":{"aa":"OPG074: S13L; OPG149: S112L; OPG193: F263L"}}},{"name":"OP881944","node_attrs":{"div":63,"accession":"OP881944","author":{"author":"Gigante,C.,Moreno-Gorrin,C.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Miller,H.,Li,Y.","value":"Gigante,C.,Moreno-Gorrin,C.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Miller,H.,Li,Y."},"strain":{"value":"MPXV_USA_2022_DE0001"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP881944/2022-09-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP715817","node_attrs":{"div":65,"accession":"OP715817","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI537"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP715817/2022-06-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C28048T","C124534T","-133098T","-133099T","-133100T","-133101T","-133102T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-"]}}},{"name":"OR463714","node_attrs":{"div":66,"accession":"OR463714","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI766"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OR463714/2022-07-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G128898A","G134674A","G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G172243A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","A181253-"],"OPG150":["D374N"],"OPG200":["E32K"]},"labels":{"aa":"OPG150: D374N; OPG200: E32K"}}}]},{"name":"NODE_0000132","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C57173T"]}},"children":[{"name":"OP480408","node_attrs":{"div":65,"accession":"OP480408","author":{"author":"Deanhardt,B.,Miller,M.,Wang,J.R.","value":"Deanhardt,B.,Miller,M.,Wang,J.R."},"strain":{"value":"hMPXV/USA/NC-UNC-0007/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP480408/2022-08-05"},"country":{"value":"USA"},"institution":{"value":"University of North Carolina at Chapel Hill, Department of Genetics"},"date":{"value":"2022-08-05"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","A31053G","C173533A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG047":["C48R"]},"labels":{"aa":"OPG047: C48R"}}},{"name":"OP727822","node_attrs":{"div":70,"accession":"OP727822","author":{"author":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K.","value":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K."},"strain":{"value":"PrEV_case_2"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OP727822/2022-10-02"},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-10-02"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["T604-","T605-","T606-","C11401T","C33964T","C36267T","G110285A","T133102-","C144366T","A174924T","G180608A","A188351-","G195316A"],"OPG052":["R11Q"],"OPG055":["D273N"],"OPG209":["E31K"]},"labels":{"aa":"OPG052: R11Q; OPG055: D273N; OPG209: E31K"}}},{"name":"NODE_0000133","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C142797T"],"OPG164":["S7L"]},"labels":{"aa":"OPG164: S7L"}},"children":[{"name":"OP279036","node_attrs":{"div":64,"accession":"OP279036","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"strain":{"value":"MpxV/human/CAN/UN-NML-4112/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OP279036/2022-06-30"},"country":{"value":"Canada"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-30"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP920699","node_attrs":{"div":70,"accession":"OP920699","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00361/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP920699/2022-10-31"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-10-31"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G105325A","C108658T","G111379A","C149889T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G165395A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G184244A"],"OPG124":["S215F"],"OPG130":["S175L"],"OPG190":["E92K"]},"labels":{"aa":"OPG124: S215F; OPG130: S175L; OPG190: E92K"}}},{"name":"OR264464","node_attrs":{"div":64,"accession":"OR264464","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain":{"value":"9_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Australia/OR264464/2022-08-19"},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-19"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","T76084-","T76085-","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG044":["K147-"]},"labels":{"aa":"OPG044: K147-"}}},{"name":"OR264396","node_attrs":{"div":69,"accession":"OR264396","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain":{"value":"33_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Australia/OR264396/2022-09-07"},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-09-07"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G14622A","A28529-","A28530-","T76084-","T76085-","G101241A","T133102-","C136244T","C156446T","G174708A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG025":["R216C"],"OPG044":["K147-"],"OPG153":["R475K"],"OPG204":["M59I"]},"labels":{"aa":"OPG025: R216C; OPG044: K147-; OPG153: R475K; OPG204: M59I"}}},{"name":"OR209323","node_attrs":{"div":65,"accession":"OR209323","author":{"author":"Li,C.M.","value":"Li,C.M."},"strain":{"value":"MPXV_USA_2022_NC0003"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR209323/2022-12-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-12-XX"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["T606-","G62268A","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","A196614-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OR759178","node_attrs":{"div":68,"accession":"OR759178","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain":{"value":"hMpxV/Canada/ON-PHOL090/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OR759178/2022-09-01"},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["T606-","G26352A","C30137T","C55072T","G130068A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"],"OPG042":["A249V"],"OPG047":["R353K"],"OPG073":["D24N"],"OPG151":["R382Q"]},"labels":{"aa":"OPG042: A249V; OPG047: R353K; OPG073: D24N; OPG151: R382Q"}}},{"name":"NODE_0000134","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C55036T","C96914T","G158254A","C170381T","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179176A","-179177T","-179178A","-179179T","-179180A"],"OPG073":["E36K"],"OPG117":["S289L"],"OPG198":["S115L"]},"labels":{"aa":"OPG073: E36K; OPG117: S289L; OPG198: S115L"}},"children":[{"name":"OQ918697","node_attrs":{"div":72,"accession":"OQ918697","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00486/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ918697/2023-02-18"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-02-18"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G73789A","C136435T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C166803T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","G178559A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG094":["G4R"],"OPG192":["P25S"]},"labels":{"aa":"OPG094: G4R; OPG192: P25S"}}},{"name":"OR464216","node_attrs":{"div":68,"accession":"OR464216","author":{"author":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y.","value":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y."},"strain":{"value":"MPXV_USA_2022_KS0007"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR464216/2022-11-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-11-XX"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T"]}}}]}]}]}]},{"name":"NODE_0000175","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G190660A"],"OPG016":["R84K"]},"labels":{"aa":"OPG016: R84K","clade":"B.1.3"}},"children":[{"name":"OP150924","node_attrs":{"div":63,"accession":"OP150924","author":{"author":"Gigante,C.,Ventura,J.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Sheth,M.,Li,Y.","value":"Gigante,C.,Ventura,J.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Sheth,M.,Li,Y."},"strain":{"value":"MPXV_USA_2022_CA006"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP150924/2022-06-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["C17752T"],"OPG030":["E28K"]},"labels":{"aa":"OPG030: E28K"}}},{"name":"ON983168","node_attrs":{"div":62,"accession":"ON983168","author":{"author":"Chmel,M.,Pajer,P.,Nagy,A.,Zlamal,M.,Jirincova,H.,Dresler,J.,Bartos,O.","value":"Chmel,M.,Pajer,P.,Nagy,A.,Zlamal,M.,Jirincova,H.,Dresler,J.,Bartos,O."},"strain":{"value":"MPxV/Prague_001/2022/flye_medaka"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Czech Republic/ON983168/2022-04-28"},"country":{"value":"Czech Republic"},"institution":{"value":"Military Heatlh Institute, Military Heatlh Institute in Prague"},"date":{"value":"2022-04-28"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["T80849-"]}}},{"name":"NODE_0000176","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["C17196T","C39898T","C148933T","G171318A","C175241T"],"OPG057":["D100N"],"OPG174":["E155K"],"OPG199":["E111K"],"OPG204":["S237L"]},"labels":{"aa":"OPG057: D100N; OPG174: E155K; OPG199: E111K; OPG204: S237L"}},"children":[{"name":"OP205116","node_attrs":{"div":67,"accession":"OP205116","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPXV_UK_2022_9000158"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP205116/2022-07-07"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-07"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"]}}},{"name":"OP536779","node_attrs":{"div":67,"accession":"OP536779","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"9000403"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP536779/2022-09-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["T606-","A62041-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"]}}}]},{"name":"NODE_0000177","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["C64426T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}},"children":[{"name":"OQ721953","node_attrs":{"div":70,"accession":"OQ721953","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"strain":{"value":"MPXV/human/Taiwan/110-525030/2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Taiwan/OQ721953/2023-03-XX"},"country":{"value":"Taiwan"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"date":{"value":"2023-03-XX"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C166940T","T177665A","A177666T","A177667T","G178104T","G178290T","T178629A","C179181-","A179189-","G196412A"],"OPG205":["N670K","N671F"]},"labels":{"aa":"OPG205: N670K, N671F"}}},{"name":"NODE_0000178","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["G55133A"],"OPG074":["R665C"]},"labels":{"aa":"OPG074: R665C"}},"children":[{"name":"ON782054","node_attrs":{"div":66,"accession":"ON782054","author":{"author":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0001a/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Spain/ON782054/2022-05-31"},"country":{"value":"Spain"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"date":{"value":"2022-05-31"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["G50337A","A122238T","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A169759G","C179181-","A179189-","A193392G","T193688C","T194099C","T194619C","T195948C","-196615A"],"OPG001_dup":["L105S"],"OPG002_dup":["F54S"],"OPG003_dup":["N264D"],"OPG069":["G118R"],"OPG143":["S360T"]},"labels":{"aa":"OPG001_dup: L105S; OPG002_dup: F54S; OPG003_dup: N264D; OPG069: G118R; OPG143: S360T"}}},{"name":"ON792320","node_attrs":{"div":65,"accession":"ON792320","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba6449f/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Switzerland/ON792320/2022-06-01"},"country":{"value":"Switzerland"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"date":{"value":"2022-06-01"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["G159376A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG185":["D154N"]},"labels":{"aa":"OPG185: D154N"}}},{"name":"ON782021","node_attrs":{"div":64,"accession":"ON782021","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O."},"strain":{"value":"MPX-37/Finland/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Finland/ON782021/2022-05-24"},"country":{"value":"Finland"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"date":{"value":"2022-05-24"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179181-","A179189-"]}}},{"name":"ON755256","node_attrs":{"div":65,"accession":"ON755256","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/RKI050"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/ON755256/2022-06-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["A36620C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179181-","A179189-"],"OPG055":["V155G"]},"labels":{"aa":"OPG055: V155G"}}},{"name":"ON754984","node_attrs":{"div":64,"accession":"ON754984","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain":{"value":"MPXV_SI2022_S3"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Slovenia/ON754984/2022-06-XX"},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["A240-","-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON622722","node_attrs":{"div":65,"accession":"ON622722","strain":{"value":"MPXV_FR_HCL0001_2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"France/ON622722/2022-05-22"},"country":{"value":"France"},"institution":{"value":"Virology, GENomique EPIdemiologique das maladies Infectieuses, France"},"date":{"value":"2022-05-22"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["C109627A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG129":["A460S"]},"labels":{"aa":"OPG129: A460S"}}},{"name":"ON609725","node_attrs":{"div":65,"accession":"ON609725","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Skubic,C.,Rozman,D.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Skubic,C.,Rozman,D.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain":{"value":"SLO"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Slovenia/ON609725/2022-05-23"},"country":{"value":"Slovenia"},"institution":{"value":"Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia"},"date":{"value":"2022-05-23"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["T157-","-607T","G167517A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG193":["E62K"]},"labels":{"aa":"OPG193: E62K"}}},{"name":"OP257258","node_attrs":{"div":65,"accession":"OP257258","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-086040/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OP257258/2022-08-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["G143066A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG164":["D97N"]},"labels":{"aa":"OPG164: D97N"}}},{"name":"OP205133","node_attrs":{"div":65,"accession":"OP205133","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPXV_UK_2022_9000188"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP205133/2022-06-29"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-29"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["-607T","C142545T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG163":["S115F"]},"labels":{"aa":"OPG163: S115F"}}},{"name":"OP205067","node_attrs":{"div":64,"accession":"OP205067","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"MPXV_UK_2022_9000061"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP205067/2022-05-27"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-05-27"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OP536757","node_attrs":{"div":64,"accession":"OP536757","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain":{"value":"9000377"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"United Kingdom/OP536757/2022-08-XX"},"country":{"value":"United Kingdom"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"]}}},{"name":"OP615322","node_attrs":{"div":64,"accession":"OP615322","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI451"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP615322/2022-09-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OP605581","node_attrs":{"div":68,"accession":"OP605581","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain":{"value":"Slovenia-MPXV-40-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Slovenia/OP605581/2022-08-XX"},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["A204-","-607T","C8612T","G52232A","C56018T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G187156A"],"OPG071":["S736L"],"OPG074":["E370K"]},"labels":{"aa":"OPG071: S736L; OPG074: E370K"}}},{"name":"OP605568","node_attrs":{"div":67,"accession":"OP605568","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain":{"value":"Slovenia-MPXV-26-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Slovenia/OP605568/2022-07-XX"},"country":{"value":"Slovenia"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["C12426T","C44716T","C141194T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG023":["E159K"],"OPG064":["E395K"]},"labels":{"aa":"OPG023: E159K; OPG064: E395K"}}},{"name":"OP555633","node_attrs":{"div":65,"accession":"OP555633","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0562/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555633/2022-09-01"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168066T","C179181-","A179189-"],"OPG153":["D385-"],"OPG193":["Q245*"]},"labels":{"aa":"OPG153: D385-; OPG193: Q245*"}}},{"name":"OP555564","node_attrs":{"div":64,"accession":"OP555564","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0488/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555564/2022-08-11"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-11"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["T606-","A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179181-","A179189-","A196614-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OQ274888","node_attrs":{"div":64,"accession":"OQ274888","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI669"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ274888/2022-05-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OQ054220","node_attrs":{"div":65,"accession":"OQ054220","author":{"author":"Gigante,C.,Hottel,W.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nelson,M.,Li,Y.","value":"Gigante,C.,Hottel,W.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nelson,M.,Li,Y."},"strain":{"value":"MPXV_USA_2022_IA0001"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OQ054220/2022-09-XX"},"country":{"value":"USA"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["T606-","G3764A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","C193446T","A196614-"],"OPG003":["L282F"],"OPG003_dup":["L282F"]},"labels":{"aa":"OPG003: L282F; OPG003_dup: L282F"}}},{"name":"OP894031","node_attrs":{"div":68,"accession":"OP894031","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI611"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OP894031/2022-08-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["T133094-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","G144669A","G145790A","G168044A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","G181052-","C182177T"],"OPG209":["G179-"]},"labels":{"aa":"OPG209: G179-"}}},{"name":"OR035715","node_attrs":{"div":64,"accession":"OR035715","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_109"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR035715/2022-10-28"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"]}}},{"name":"OR035686","node_attrs":{"div":65,"accession":"OR035686","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_80"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR035686/2022-08-09"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-09"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["C22950T","T133101-","T133102-","C133161T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR353541","node_attrs":{"div":66,"accession":"OR353541","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"strain":{"value":"MN-MDH-MPXV_0031"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR353541/2022-07-28"},"country":{"value":"USA"},"institution":{"value":"Minnesota Department of Health, Public Health Laboratory"},"date":{"value":"2022-07-28"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["G13224A","G100344C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179181-","A179189-"],"OPG024":["S2L"]},"labels":{"aa":"OPG024: S2L"}}},{"name":"OR264391","node_attrs":{"div":64,"accession":"OR264391","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain":{"value":"2_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Australia/OR264391/2022-08-10"},"country":{"value":"Australia"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-10"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["T80846-","T80847-","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OR134560","node_attrs":{"div":75,"accession":"OR134560","author":{"author":"Miller,H.,Bajwa,M.","value":"Miller,H.,Bajwa,M."},"strain":{"value":"B1221136"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR134560/2023-03-13"},"country":{"value":"USA"},"institution":{"value":"Delaware Public Health Lab, Sequencing/Bioinformatics"},"date":{"value":"2023-03-13"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["C19558T","G32277A","C35688T","G39140A","G55059A","G75512A","C110402T","C121161T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C170673T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179181-","A179189-","C179542T","C189174T"],"OPG034":["E150K"],"OPG049":["S292L"],"OPG073":["S28L"],"OPG095":["R237K"],"OPG139":["A70T"]},"labels":{"aa":"OPG034: E150K; OPG049: S292L; OPG073: S28L; OPG095: R237K; OPG139: A70T"}}},{"name":"OX248696","node_attrs":{"div":66,"accession":"OX248696","strain":{"value":"RNA"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Slovakia/OX248696/2022-07-04"},"country":{"value":"Slovakia"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"date":{"value":"2022-07-04"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["T606-","G37250A","C138080T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179181-","A179189-","A196614-"],"OPG155":["E138K"]},"labels":{"aa":"OPG155: E138K"}}},{"name":"OR759179","node_attrs":{"div":66,"accession":"OR759179","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain":{"value":"hMpxV/Canada/ON-PHOL091/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Canada/OR759179/2022-09-01"},"country":{"value":"Canada"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["G85581A","C122502T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179181-","A179189-"],"OPG107":["V24I"],"OPG143":["D272N"]},"labels":{"aa":"OPG107: V24I; OPG143: D272N"}}},{"name":"OR463729","node_attrs":{"div":69,"accession":"OR463729","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2022/ON/RKI763"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OR463729/2022-07-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["C73634T","G91811A","G148578A","C149527T","G150551-","T150564-","G150565-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C153729T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","A181253-"],"OPG174":["S273F"],"OPG175":["S29L"]},"labels":{"aa":"OPG174: S273F; OPG175: S29L"}}},{"name":"NODE_0000179","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["A140126-","C140127-","T168120C","-179234A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-"],"OPG159":["N120-"],"OPG193":["F263L"]},"labels":{"aa":"OPG159: N120-; OPG193: F263L"}},"children":[{"name":"OP144214","node_attrs":{"div":66,"accession":"OP144214","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P."},"strain":{"value":"MPXV/ITM_pt_25/Belgium/16-Jun-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OP144214/2022-06-16"},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-06-16"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["C133161T","C157632T"]}}},{"name":"ON950045","node_attrs":{"div":65,"accession":"ON950045","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,Van den Bossche,D.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Van Esbroeck,M.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,Van den Bossche,D.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Van Esbroeck,M."},"strain":{"value":"MPXV/ITM_pt_31/Belgium/27-May-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/ON950045/2022-05-27"},"country":{"value":"Belgium"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-05-27"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["T133102-","A140104-","A140105-","T140106-","A140107-","A140108-","C140109-","A140110-","A140111-","T140112-","T140113-","A140114-","T140115-","A140116-","A140117-","C140118-","A140119-","A140120-","T140121-","T140122-","A140123-","T140124-","A140125-","A140128-","A140129-","T140130-","T140131-","A140132-","T140133-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","A140143-","A140144-","T140145-","T140146-","G140147-","T140148-","T140149-","A140150-","T140151-","A140152-","A140153-","T140154-","A140155-","A140156-","T140157-","T140158-","A140159-","T140160-","A140161-","A140162-","T140163-","T140164-","G140165-","T140166-","T140167-","T179267-","-196615A"],"OPG159":["N113-","N114-","N115-","Y116-","N117-","N118-","Y119-","N121-","Y122-","N123-","N124-","Y125-","N126-","C127-","Y128-","N129-","N130-","Y131-","N132-","C133-","Y134-"]},"labels":{"aa":"OPG159: N113-, N114-, N115-, Y116-, N117-, N118-, Y119-, N121-, Y122-, N123-, N124-, Y125-, N126-, C127-, Y128-, N129-, N130-, Y131-, N132-, C133-, Y134-"}}}]},{"name":"NODE_0000180","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["C133161T","C157632T"]}},"children":[{"name":"OP555472","node_attrs":{"div":66,"accession":"OP555472","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"Monkeypox/PT0376/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OP555472/2022-07-07"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-07"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159243A","C179181-","A179189-"]}}},{"name":"OR086974","node_attrs":{"div":66,"accession":"OR086974","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_165/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR086974/2022-07-27"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-27"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["G41336A","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000181","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["G152776A","C179181-","A179189-"],"OPG180":["D29N"]},"labels":{"aa":"OPG180: D29N"}},"children":[{"name":"OQ451904","node_attrs":{"div":76,"accession":"OQ451904","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2023/RKI719"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OQ451904/2023-01-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2023-01-XX"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["-607T","C15969T","C17998T","G40610A","C43803T","C63879T","G70190A","G118289A","C147011T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C159532T","G161629A","C189427T"],"OPG005":["P77S"],"OPG027":["E137K"],"OPG031":["M277I"],"OPG064":["G699E"],"OPG083":["D280N"],"OPG089":["E109K"],"OPG185":["P206S"],"OPG188":["E12K"]},"labels":{"aa":"OPG005: P77S; OPG027: E137K; OPG031: M277I; OPG064: G699E; OPG083: D280N; OPG089: E109K; OPG185: P206S; OPG188: E12K"}}},{"name":"OQ581854","node_attrs":{"div":67,"accession":"OQ581854","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"strain":{"value":"MPXV/human/Taiwan/109-005210/2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Taiwan/OQ581854/2023-02-XX"},"country":{"value":"Taiwan"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"date":{"value":"2023-02-XX"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["T64426C","G158406A","A192404-","G192405-","T192406-","A192411-"]}}}]},{"name":"NODE_0000182","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["G105923A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179181-","A179189-"],"OPG124":["L16F"]},"labels":{"aa":"OPG124: L16F","clade":"C.1"}},"children":[{"name":"LC753970","node_attrs":{"div":65,"accession":"LC753970","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220187"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Japan/LC753970/2022-10-XX"},"country":{"value":"Japan"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"date":{"value":"2022-10-XX"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{}}},{"name":"LC753968","node_attrs":{"div":65,"accession":"LC753968","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220165"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Japan/LC753968/2022-09-XX"},"country":{"value":"Japan"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"date":{"value":"2022-09-XX"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{}}},{"name":"OR035728","node_attrs":{"div":66,"accession":"OR035728","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain":{"value":"MPXV/UZ_REGA_122"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Belgium/OR035728/2022-10-28"},"country":{"value":"Belgium"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G149818A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG176":["D4N"]},"labels":{"aa":"OPG176: D4N"}}},{"name":"OQ581853","node_attrs":{"div":67,"accession":"OQ581853","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"strain":{"value":"MPXV/human/Taiwan/110-093831/2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Taiwan/OQ581853/2023-02-XX"},"country":{"value":"Taiwan"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"date":{"value":"2023-02-XX"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["T132513C","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C185069T"]}}},{"name":"NODE_0000183","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["C3987T"]}},"children":[{"name":"OQ721954","node_attrs":{"div":71,"accession":"OQ721954","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"strain":{"value":"MPXV/human/Taiwan/110-539498/2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Taiwan/OQ721954/2023-03-XX"},"country":{"value":"Taiwan"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"date":{"value":"2023-03-XX"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["-607T","C798T","C11923T","T14737C","C48442T","G90825A","G102694A","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A191312G","G196412A"],"OPG015_dup":["I87V"],"OPG068":["A81V"]},"labels":{"aa":"OPG015_dup: I87V; OPG068: A81V"}}},{"name":"NODE_0000184","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["C166940T","G193223A"]}},"children":[{"name":"LC760461","node_attrs":{"div":68,"accession":"LC760461","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A."},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220343"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Japan/LC760461/2023-02-13"},"country":{"value":"Japan"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"date":{"value":"2023-02-13"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["C798T","C68765T","G196412A"],"OPG086":["M33I"]},"labels":{"aa":"OPG086: M33I"}}},{"name":"LC756923","node_attrs":{"div":67,"accession":"LC756923","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220318"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Japan/LC756923/2023-01-25"},"country":{"value":"Japan"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"date":{"value":"2023-01-25"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{}}},{"name":"OR427348","node_attrs":{"div":70,"accession":"OR427348","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-066957/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR427348/2023-06-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-06-XX"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["G26855A","C30191T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C155490T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG047":["R335H"]},"labels":{"aa":"OPG047: R335H"}}},{"name":"OR665166","node_attrs":{"div":72,"accession":"OR665166","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain":{"value":"MpxV/human/USA/WA-UW-092809/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR665166/2023-09-XX"},"country":{"value":"USA"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-09-XX"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["T606-","G13434A","G29650A","C33332T","G37974A","C74691T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG025":["R612C"],"OPG046":["T27I"],"OPG050":["R26Q"],"OPG056":["S354L"]},"labels":{"aa":"OPG025: R612C; OPG046: T27I; OPG050: R26Q; OPG056: S354L"}}},{"name":"OR499979","node_attrs":{"div":70,"accession":"OR499979","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00522/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR499979/2023-05-08"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-05-08"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["G11924A","C134237T","G178951A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG023":["S326L"]},"labels":{"aa":"OPG023: S326L"}}},{"name":"OR459795","node_attrs":{"div":70,"accession":"OR459795","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain":{"value":"MPXV-ROK-P022-2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"South Korea/OR459795/2023-04-21"},"country":{"value":"South Korea"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2023-04-21"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["G39380A","C139775T","G152650A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG159":["S3F"]},"labels":{"aa":"OPG159: S3F"}}},{"name":"NODE_0000185","node_attrs":{"div":69,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["C149963T","G184562A"],"OPG176":["S52L"]},"labels":{"aa":"OPG176: S52L"}},"children":[{"name":"OR459778","node_attrs":{"div":70,"accession":"OR459778","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain":{"value":"MPXV-ROK-P005-2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"South Korea/OR459778/2023-03-13"},"country":{"value":"South Korea"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2023-03-13"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["G85691A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000186","node_attrs":{"div":72,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["C21062T","G188348A","C188946T","A196663-","A196664-"],"OPG036":["M1I"]},"labels":{"aa":"OPG036: M1I"}},"children":[{"name":"OR643705","node_attrs":{"div":78,"accession":"OR643705","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00563/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"USA/OR643705/2023-08-16"},"country":{"value":"USA"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-08-16"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["G21880A","G47532A","C125074T","G133704A","G133838A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T180483A"],"OPG037":["S185F"]},"labels":{"aa":"OPG037: S185F"}}},{"name":"NODE_0000187","node_attrs":{"div":74,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["G101241A","G152866A"],"OPG180":["D59N"]},"labels":{"aa":"OPG180: D59N"}},"children":[{"name":"OR743500","node_attrs":{"div":77,"accession":"OR743500","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2023/ON/RKI1031"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OR743500/2023-10-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2023-10-XX"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["T57476C","C142797T","G173397A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-"],"OPG075":["Q8R"],"OPG164":["S7L"]},"labels":{"aa":"OPG075: Q8R; OPG164: S7L"}}},{"name":"NODE_0000188","node_attrs":{"div":75,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["G13563A","C191053-","A191054-","T191055-","G191056-","G191057-","A191058-","G191059-","T191060-","C191061-","G191062-","G191063-","T191064-","A191065-","G191066-","A191067-","T191068-","T191069-","T191070-","C191071-","A191072-","T191073-","G191074-","G191075-","C191076-","T191077-","G191078-","T191079-","C191080-","G191081-","A191082-","T191083-","G191084-","A191085-","G191086-","C191087-","A191088-","G191089-","T191090-","T191091-","T191092-","C191093-","A191094-","C191095-","G191096-","A191097-","C191098-","G191099-","A191100-","C191101-","C191102-","T191103-","C191104-","G191105-","A191106-","T191107-","C191108-","T191109-","T191110-","T191111-","G191112-","G191113-","T191114-","C191115-","A191116-","T191117-","T191118-","A191119-","T191120-","C191121-","T191122-","T191123-","T191124-","G191125-","G191126-","T191127-","A191128-","G191129-"],"OPG025":["P569S"]},"labels":{"aa":"OPG025: P569S"}},"children":[{"name":"OR326993","node_attrs":{"div":75,"accession":"OR326993","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"MPXV/PT0629/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OR326993/2023-06-20"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-06-20"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"]}}},{"name":"OR488000","node_attrs":{"div":78,"accession":"OR488000","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"MPXV/PT0682/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OR488000/2023-08-07"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-08-07"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["G49821A","G87187A","C190352T"],"OPG068":["E541K"],"OPG109":["S754L"]},"labels":{"aa":"OPG068: E541K; OPG109: S754L"}}},{"name":"NODE_0000189","node_attrs":{"div":77,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["T781-","C37738T","G151847A"],"OPG056":["E433K"]},"labels":{"aa":"OPG056: E433K"}},"children":[{"name":"OR449307","node_attrs":{"div":82,"accession":"OR449307","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain":{"value":"MPXV/Germany/2023/ON/RKI1021"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Germany/OR449307/2023-08-XX"},"country":{"value":"Germany"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2023-08-XX"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["-781T","C56879T","C57492T","C84191T","C115068T","G121291A","A179169-","T179170-","A179171-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG074":["E83K"],"OPG075":["E3K"],"OPG133":["R210K"]},"labels":{"aa":"OPG074: E83K; OPG075: E3K; OPG133: R210K"}}},{"name":"OR487983","node_attrs":{"div":77,"accession":"OR487983","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain":{"value":"MPXV/PT0661/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"strain_display":{"value":"Portugal/OR487983/2023-07-26"},"country":{"value":"Portugal"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-07-26"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["C780-"]}}}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}} \ No newline at end of file diff --git a/data_output/nextstrain/mpox/clade-iib/unreleased/CHANGELOG.md b/data_output/nextstrain/mpox/clade-iib/unreleased/CHANGELOG.md new file mode 100644 index 00000000..1a0c18a8 --- /dev/null +++ b/data_output/nextstrain/mpox/clade-iib/unreleased/CHANGELOG.md @@ -0,0 +1,13 @@ +## Unreleased + +Initial release of this dataset. This dataset is similar to the v2 dataset [`hMPXV/NC_063383.1`](https://github.com/nextstrain/nextclade_data/tree/2023-08-17--15-51-24--UTC/data/datasets/hMPXV/references/NC_063383.1/versions/2023-08-01T12%3A00%3A00Z/files) with some differences. + +### New and changed gene names + +Some genes have been renamed and one has been added. The new annotation is based on NCBI refseq annotations that were released in November 2022. The v2 dataset predates this refseq: + +- The 4 genes in the inverted terminal repeat segment (ITR) on both ends of the genome (OPG001, OPG002, OPG003,OPG015) are now all included. The genes on the 3' end (~positions 190000-197000) now have an `_dup` appended to distinguish them. +- The gene previously named `NBT03_gp052` is now called `OPG073` +- The gene previously named `NBT03_gp174` is now called `OPG016` +- The gene previously named `NBT03_gp175` is now called `OPG015_dup` +- Gene `OPG166` has been added diff --git a/data_output/nextstrain/mpox/clade-iib/unreleased/README.md b/data_output/nextstrain/mpox/clade-iib/unreleased/README.md new file mode 100644 index 00000000..ea947155 --- /dev/null +++ b/data_output/nextstrain/mpox/clade-iib/unreleased/README.md @@ -0,0 +1,23 @@ +# Nextclade dataset for "Mpox virus (Clade IIb)" + +| Key | Value | +| ---------------------- | --------------------------------------------------------------------------------------------------------------------- | +| authors | [Cornelius Roemer](https://neherlab.org), [Richard Neher](https://neherlab.org), [Nextstrain](https://nextstrain.org) | +| data source | Genbank | +| workflow | [github.com/nextstrain/mpox/nextclade](https://github.com/nextstrain/mpox/nextclade) | +| nextclade dataset path | nextstrain/mpox/clade-iib | +| annotation | [NC_063383.1](https://www.ncbi.nlm.nih.gov/nuccore/NC_063383) | +| clade definitions | [github.com/mpxv-lineages/lineage-designation](https://github.com/mpxv-lineages/lineage-designation) | +| related datasets | Mpox virus (All clades): `nextstrain/mpox/all-clades`
Mpox virus (Lineage B.1) `nextstrain/mpox/lineage-b.1` | + +This dataset is for Mpox viruses of clade IIb. A more specific dataset just for outbreak lineage B.1 is available as `nextstrain/mpox/lineage-b.1`. There is also a broader dataset for all clades I, IIa and IIb under `nextstrain/mpox/all-clades`. + +The lineage system used is defined in [Happi et al. (2022)](https://doi.org/10.1371/journal.pbio.3001769). Lineage definitions are available at [github.com/mpxv-lineages/lineage-designation](https://github.com/nextstrain/mpox/nextclade). + +The reference used in this dataset is the clade IIb NCBI refseq `NC_063383.1` (Isolate `MPXV-M5312_HM12_Rivers`). + +The reference tree consists of around 5000 sequences with representatives from all clade IIb lineages. + +## Further reading + +Read more about Nextclade datasets in Nextclade documentation: https://docs.nextstrain.org/projects/nextclade/en/stable/user/datasets.html diff --git a/data_output/nextstrain/mpox/clade-iib/unreleased/genome_annotation.gff3 b/data_output/nextstrain/mpox/clade-iib/unreleased/genome_annotation.gff3 new file mode 100644 index 00000000..432d5465 --- /dev/null +++ b/data_output/nextstrain/mpox/clade-iib/unreleased/genome_annotation.gff3 @@ -0,0 +1,391 @@ +##gff-version 3 +#!gff-spec-version 1.21 +#!processor NCBI annotwriter +##sequence-region NC_063383.1 1 197209 +##species https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10244 +NC_063383.1 RefSeq region 1 197209 . + . ID=NC_063383.1:1..197209;Dbxref=taxon:10244;collection-date=2018-08;country=Nigeria: Rivers State;gbkey=Src;genome=genomic;genotype=MPXV clade 2;isolate=MPXV-M5312_HM12_Rivers;mol_type=genomic DNA;nat-host=Homo sapiens +NC_063383.1 RefSeq long_terminal_repeat 1 6422 . - . ID=id-NC_063383.1:1..6422;gbkey=repeat_region;rpt_type=long_terminal_repeat +NC_063383.1 RefSeq gene 835 1575 . - . ID=gene-NBT03_gp001;Dbxref=GeneID:72551607;Name=OPG001;gbkey=Gene;gene=OPG001;gene_biotype=protein_coding;locus_tag=NBT03_gp001;old_locus_tag=MPXV-M5312_HM12_Rivers-001 +NC_063383.1 RefSeq CDS 835 1575 . - 0 ID=cds-YP_010377002.1;Parent=gene-NBT03_gp001;Dbxref=GenBank:YP_010377002.1,GeneID:72551607;Name=OPG001;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp001%3B Chemokine binding protein (Cop-C23L)%3B most abundant secreted protein%3B CC-chemokine binding%3B similar to VACV-WR J1L and VACV-Cop C23L;gbkey=CDS;gene=OPG001;locus_tag=NBT03_gp001;product=Chemokine binding protein;protein_id=YP_010377002.1 +NC_063383.1 RefSeq gene 1702 2751 . - . ID=gene-NBT03_gp002;Dbxref=GeneID:72551418;Name=OPG002;gbkey=Gene;gene=OPG002;gene_biotype=protein_coding;locus_tag=NBT03_gp002;old_locus_tag=MPXV-M5312_HM12_Rivers-002 +NC_063383.1 RefSeq CDS 1702 2751 . - 0 ID=cds-YP_010377003.1;Parent=gene-NBT03_gp002;Dbxref=GenBank:YP_010377003.1,GeneID:72551418;Name=OPG002;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: NBT03_gp002%3B TNF receptor (CrmB)%3B similar to VACV-WR J2L and VACV-Cop C22L;gbkey=CDS;gene=OPG002;locus_tag=NBT03_gp002;product=Crm-B secreted TNF-alpha-receptor-like protein;protein_id=YP_010377003.1 +NC_063383.1 RefSeq gene 2841 4607 . - . ID=gene-NBT03_gp003;Dbxref=GeneID:72551419;Name=OPG003;gbkey=Gene;gene=OPG003;gene_biotype=protein_coding;locus_tag=NBT03_gp003;old_locus_tag=MPXV-M5312_HM12_Rivers-003 +NC_063383.1 RefSeq CDS 2841 4607 . - 0 ID=cds-YP_010377004.1;Parent=gene-NBT03_gp003;Dbxref=GenBank:YP_010377004.1,GeneID:72551419;Name=OPG003;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp003%3B Ankyrin%3B similar to VACV-WR J3L and VACV-Cop C19L;gbkey=CDS;gene=OPG003;locus_tag=NBT03_gp003;product=Ankyrin repeat protein (25);protein_id=YP_010377004.1 +NC_063383.1 RefSeq gene 4843 6156 . - . ID=gene-NBT03_gp004;Dbxref=GeneID:72551420;Name=OPG015;gbkey=Gene;gene=OPG015;gene_biotype=protein_coding;locus_tag=NBT03_gp004;old_locus_tag=MPXV-M5312_HM12_Rivers-004 +NC_063383.1 RefSeq CDS 4843 6156 . - 0 ID=cds-YP_010377005.1;Parent=gene-NBT03_gp004;Dbxref=GenBank:YP_010377005.1,GeneID:72551420;Name=OPG015;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp004%3B Ankyrin%3B similar to VACV-WR D1L and CPXV-017;gbkey=CDS;gene=OPG015;locus_tag=NBT03_gp004;product=Ankyrin repeat protein (39);protein_id=YP_010377005.1 +NC_063383.1 RefSeq sequence_feature 6270 6419 . - . ID=id-NC_063383.1:6270..6419;exon_number=OPG016;gbkey=misc_feature;number=OPG016 +NC_063383.1 RefSeq sequence_feature 6444 6885 . - . ID=id-NC_063383.1:6444..6885;exon_number=OPG017;gbkey=misc_feature;number=OPG017 +NC_063383.1 RefSeq sequence_feature 6966 7463 . - . ID=id-NC_063383.1:6966..7463;exon_number=OPG018;gbkey=misc_feature;number=OPG018 +NC_063383.1 RefSeq gene 7580 8008 . + . ID=gene-NBT03_gp005;Dbxref=GeneID:72551421;Name=OPG019;gbkey=Gene;gene=OPG019;gene_biotype=protein_coding;locus_tag=NBT03_gp005;old_locus_tag=MPXV-M5312_HM12_Rivers-006 +NC_063383.1 RefSeq CDS 7580 8008 . + 0 ID=cds-YP_010377006.1;Parent=gene-NBT03_gp005;Dbxref=GenBank:YP_010377006.1,GeneID:72551421;Name=OPG019;Note=Taxonomic breadth: chordopoxvirinae%3B secreted growth factor Secreted EGF-like protein%3B similar to VACV-WR D3R and VACV-Cop C11R;gbkey=CDS;gene=OPG019;locus_tag=NBT03_gp005;product=EGF-like domain protein;protein_id=YP_010377006.1 +NC_063383.1 RefSeq sequence_feature 8136 9102 . - . ID=id-NC_063383.1:8136..9102;exon_number=OPG020;gbkey=misc_feature;number=OPG020 +NC_063383.1 RefSeq gene 9587 10315 . + . ID=gene-NBT03_gp006;Dbxref=GeneID:72551422;Name=OPG021;gbkey=Gene;gene=OPG021;gene_biotype=protein_coding;locus_tag=NBT03_gp006;old_locus_tag=MPXV-M5312_HM12_Rivers-008 +NC_063383.1 RefSeq CDS 9587 10315 . + 0 ID=cds-YP_010377007.1;Parent=gene-NBT03_gp006;Dbxref=GenBank:YP_010377007.1,GeneID:72551422;Name=OPG021;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp008%3B Zinc finger-like protein%3B zinc binding%3B virosome localization%3B virulence factor%3B inhibition of apoptosis induced by UV irradiation%3B similar to VACV-WR D5R;gbkey=CDS;gene=OPG021;locus_tag=NBT03_gp006;product=Zinc finger-like protein (2);protein_id=YP_010377007.1 +NC_063383.1 RefSeq gene 10478 10858 . - . ID=gene-NBT03_gp007;Dbxref=GeneID:72551423;Name=OPG022;gbkey=Gene;gene=OPG022;gene_biotype=protein_coding;locus_tag=NBT03_gp007;old_locus_tag=MPXV-M5312_HM12_Rivers-009 +NC_063383.1 RefSeq CDS 10478 10858 . - 0 ID=cds-YP_010377008.1;Parent=gene-NBT03_gp007;Dbxref=GenBank:YP_010377008.1,GeneID:72551423;Name=OPG022;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp009%3B secreted IL-18 binding protein%3B Soluble IL-18 binding protein (Bsh-D7L)%3B similar to VACV-WR D6L;gbkey=CDS;gene=OPG022;locus_tag=NBT03_gp007;product=Interleukin-18-binding protein;protein_id=YP_010377008.1 +NC_063383.1 RefSeq gene 10918 12900 . - . ID=gene-NBT03_gp008;Dbxref=GeneID:72551424;Name=OPG023;gbkey=Gene;gene=OPG023;gene_biotype=protein_coding;locus_tag=NBT03_gp008;old_locus_tag=MPXV-M5312_HM12_Rivers-010 +NC_063383.1 RefSeq CDS 10918 12900 . - 0 ID=cds-YP_010377009.1;Parent=gene-NBT03_gp008;Dbxref=GenBank:YP_010377009.1,GeneID:72551424;Name=OPG023;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp010%3B host range%3B ankyrin-like%3B Ankyrin/Host Range (Bang-D8L)%3B similar to VACV-WR D7L;gbkey=CDS;gene=OPG023;locus_tag=NBT03_gp008;product=Ankyrin repeat protein (2);protein_id=YP_010377009.1 +NC_063383.1 RefSeq gene 13034 13228 . - . ID=gene-NBT03_gp009;Dbxref=GeneID:72551425;Name=OPG024;gbkey=Gene;gene=OPG024;gene_biotype=protein_coding;locus_tag=NBT03_gp009;old_locus_tag=MPXV-M5312_HM12_Rivers-011 +NC_063383.1 RefSeq CDS 13034 13228 . - 0 ID=cds-YP_010377010.1;Parent=gene-NBT03_gp009;Dbxref=GenBank:YP_010377010.1,GeneID:72551425;Name=OPG024;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp011%3B ANK-containing protein%3B similar to VACV-WR D8L;gbkey=CDS;gene=OPG024;locus_tag=NBT03_gp009;product=retroviral pseudoprotease-like protein;protein_id=YP_010377010.1 +NC_063383.1 RefSeq gene 13375 15267 . - . ID=gene-NBT03_gp010;Dbxref=GeneID:72551426;Name=OPG025;gbkey=Gene;gene=OPG025;gene_biotype=protein_coding;locus_tag=NBT03_gp010;old_locus_tag=MPXV-M5312_HM12_Rivers-012 +NC_063383.1 RefSeq CDS 13375 15267 . - 0 ID=cds-YP_010377011.1;Parent=gene-NBT03_gp010;Dbxref=GenBank:YP_010377011.1,GeneID:72551426;Name=OPG025;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp012%3B ankyrin-like%3B Type I IFN resistance%3B similar to VACV-WR D9L and VACV-Cop C9L;gbkey=CDS;gene=OPG025;locus_tag=NBT03_gp010;product=Ankyrin repeat protein (14);protein_id=YP_010377011.1 +NC_063383.1 RefSeq sequence_feature 15310 15854 . - . ID=id-NC_063383.1:15310..15854;exon_number=OPG026;gbkey=misc_feature;number=OPG026 +NC_063383.1 RefSeq gene 15925 16377 . - . ID=gene-NBT03_gp011;Dbxref=GeneID:72551427;Name=OPG027;gbkey=Gene;gene=OPG027;gene_biotype=protein_coding;locus_tag=NBT03_gp011;old_locus_tag=MPXV-M5312_HM12_Rivers-013 +NC_063383.1 RefSeq CDS 15925 16377 . - 0 ID=cds-YP_010377012.1;Parent=gene-NBT03_gp011;Dbxref=GenBank:YP_010377012.1,GeneID:72551427;Name=OPG027;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp013%3B host range%3B Type 1 IFN inhibitor%3B similar to VACV-WR D10L and VACV-Cop C7L;gbkey=CDS;gene=OPG027;locus_tag=NBT03_gp011;product=Host range protein;protein_id=YP_010377012.1 +NC_063383.1 RefSeq gene 16602 17069 . - . ID=gene-NBT03_gp012;Dbxref=GeneID:72551428;Name=OPG029;gbkey=Gene;gene=OPG029;gene_biotype=protein_coding;locus_tag=NBT03_gp012;old_locus_tag=MPXV-M5312_HM12_Rivers-014 +NC_063383.1 RefSeq CDS 16602 17069 . - 0 ID=cds-YP_010377013.1;Parent=gene-NBT03_gp012;Dbxref=GenBank:YP_010377013.1,GeneID:72551428;Name=OPG029;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp014%3B Putative tlr signaling inhibitor%2C IFN-beta inhibitor%3B similar to VACV-WR D11L and VACV-Cop C6L;gbkey=CDS;gene=OPG029;locus_tag=NBT03_gp012;product=Bcl-2-like protein;protein_id=YP_010377013.1 +NC_063383.1 RefSeq gene 17213 17833 . - . ID=gene-NBT03_gp013;Dbxref=GeneID:72551429;Name=OPG030;gbkey=Gene;gene=OPG030;gene_biotype=protein_coding;locus_tag=NBT03_gp013;old_locus_tag=MPXV-M5312_HM12_Rivers-015 +NC_063383.1 RefSeq CDS 17213 17833 . - 0 ID=cds-YP_010377014.1;Parent=gene-NBT03_gp013;Dbxref=GenBank:YP_010377014.1,GeneID:72551429;Name=OPG030;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp015%3B BTB domain of kelch-like protein%3B Kelch-like protein%3B similar to VACV-WR D12L and VACV-Cop C5L;gbkey=CDS;gene=OPG030;locus_tag=NBT03_gp013;product=Kelch-like protein (1);protein_id=YP_010377014.1 +NC_063383.1 RefSeq gene 17878 18828 . - . ID=gene-NBT03_gp014;Dbxref=GeneID:72551430;Name=OPG031;gbkey=Gene;gene=OPG031;gene_biotype=protein_coding;locus_tag=NBT03_gp014;old_locus_tag=MPXV-M5312_HM12_Rivers-016 +NC_063383.1 RefSeq CDS 17878 18828 . - 0 ID=cds-YP_010377015.1;Parent=gene-NBT03_gp014;Dbxref=GenBank:YP_010377015.1,GeneID:72551430;Name=OPG031;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp016%3B IL-1 receptor antagonist%3B similar to VACV-WR D13L and VACV-Cop C10L;gbkey=CDS;gene=OPG031;locus_tag=NBT03_gp014;product=C4L/C10L-like family protein;protein_id=YP_010377015.1 +NC_063383.1 RefSeq sequence_feature 18902 19288 . - . ID=id-NC_063383.1:18902..19288;exon_number=OPG033;gbkey=misc_feature;number=OPG033 +NC_063383.1 RefSeq gene 19361 20005 . - . ID=gene-NBT03_gp015;Dbxref=GeneID:72551431;Name=OPG034;gbkey=Gene;gene=OPG034;gene_biotype=protein_coding;locus_tag=NBT03_gp015;old_locus_tag=MPXV-M5312_HM12_Rivers-018 +NC_063383.1 RefSeq CDS 19361 20005 . - 0 ID=cds-YP_010377017.1;Parent=gene-NBT03_gp015;Dbxref=GenBank:YP_010377017.1,GeneID:72551431;Name=OPG034;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp022%3B Putative TLR signalling inhibitor%3B start of ORF is missing approx. 18 AA compared to CPXVs%3B similar to VACV-WR D19L and VACV-Cop C1L;gbkey=CDS;gene=OPG034;locus_tag=NBT03_gp015;product=Bcl-2-like protein;protein_id=YP_010377017.1 +NC_063383.1 RefSeq gene 20051 20404 . - . ID=gene-NBT03_gp016;Dbxref=GeneID:72551432;Name=OPG035;gbkey=Gene;gene=OPG035;gene_biotype=protein_coding;locus_tag=NBT03_gp016;old_locus_tag=MPXV-M5312_HM12_Rivers-019 +NC_063383.1 RefSeq CDS 20051 20404 . - 0 ID=cds-YP_010377018.1;Parent=gene-NBT03_gp016;Dbxref=GenBank:YP_010377018.1,GeneID:72551432;Name=OPG035;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp023%3B secreted virulence factor%3B Putative tlr signaling inhibitor%3B Anti-apoptotic Bcl-2-like protein%3B similar to VACV-WR P1L and VACV-Cop N1L;gbkey=CDS;gene=OPG035;locus_tag=NBT03_gp016;product=Bcl-2-like protein;protein_id=YP_010377018.1 +NC_063383.1 RefSeq gene 20531 21064 . - . ID=gene-NBT03_gp017;Dbxref=GeneID:72551433;Name=OPG036;gbkey=Gene;gene=OPG036;gene_biotype=protein_coding;locus_tag=NBT03_gp017;old_locus_tag=MPXV-M5312_HM12_Rivers-020 +NC_063383.1 RefSeq CDS 20531 21064 . - 0 ID=cds-YP_010377019.1;Parent=gene-NBT03_gp017;Dbxref=GenBank:YP_010377019.1,GeneID:72551433;Name=OPG036;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp024%3B Alpha amanatin target protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR P2L and VACV-Cop #N2L;gbkey=CDS;gene=OPG036;locus_tag=NBT03_gp017;product=Bcl-2-like protein;protein_id=YP_010377019.1 +NC_063383.1 RefSeq gene 21105 22433 . - . ID=gene-NBT03_gp018;Dbxref=GeneID:72551434;Name=OPG037;gbkey=Gene;gene=OPG037;gene_biotype=protein_coding;locus_tag=NBT03_gp018;old_locus_tag=MPXV-M5312_HM12_Rivers-021 +NC_063383.1 RefSeq CDS 21105 22433 . - 0 ID=cds-YP_010377020.1;Parent=gene-NBT03_gp018;Dbxref=GenBank:YP_010377020.1,GeneID:72551434;Name=OPG037;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp025%3B ankyrin-like%3B ANK-containing protein%3B apoptosis inhibitor%3B start of ORF is missing approx. 31 AA compared to CPXVs%3B similar to VACV-WR O1L and VACV-Cop M1L;gbkey=CDS;gene=OPG037;locus_tag=NBT03_gp018;product=Ankyrin-like protein (1);protein_id=YP_010377020.1 +NC_063383.1 RefSeq gene 22497 23159 . - . ID=gene-NBT03_gp019;Dbxref=GeneID:72551435;Name=OPG038;gbkey=Gene;gene=OPG038;gene_biotype=protein_coding;locus_tag=NBT03_gp019;old_locus_tag=MPXV-M5312_HM12_Rivers-022 +NC_063383.1 RefSeq CDS 22497 23159 . - 0 ID=cds-YP_010377021.1;Parent=gene-NBT03_gp019;Dbxref=GenBank:YP_010377021.1,GeneID:72551435;Name=OPG038;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp026%3B NFkB inhibitor%3B similar to VACV-WR O2L and VACV-Cop M2L;gbkey=CDS;gene=OPG038;locus_tag=NBT03_gp019;product=NFkB inhibitor;protein_id=YP_010377021.1 +NC_063383.1 RefSeq gene 23264 24118 . - . ID=gene-NBT03_gp020;Dbxref=GeneID:72551436;Name=OPG039;gbkey=Gene;gene=OPG039;gene_biotype=protein_coding;locus_tag=NBT03_gp020;old_locus_tag=MPXV-M5312_HM12_Rivers-023 +NC_063383.1 RefSeq CDS 23264 24118 . - 0 ID=cds-YP_010377022.1;Parent=gene-NBT03_gp020;Dbxref=GenBank:YP_010377022.1,GeneID:72551436;Name=OPG039;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp027%3B host range%3B ankyrin-like%3B Ankyrin/NFkB inhibitor%3B similar to VACV-WR C1L and VACV-Cop K1L;gbkey=CDS;gene=OPG039;locus_tag=NBT03_gp020;product=Ankyrin-like protein (3);protein_id=YP_010377022.1 +NC_063383.1 RefSeq gene 24351 25478 . - . ID=gene-NBT03_gp021;Dbxref=GeneID:72551437;Name=OPG040;gbkey=Gene;gene=OPG040;gene_biotype=protein_coding;locus_tag=NBT03_gp021;old_locus_tag=MPXV-M5312_HM12_Rivers-024 +NC_063383.1 RefSeq CDS 24351 25478 . - 0 ID=cds-YP_010377023.1;Parent=gene-NBT03_gp021;Dbxref=GenBank:YP_010377023.1,GeneID:72551437;Name=OPG040;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp028%3B serine protease inhibitor-like%2C SPI-3%3B inhibition of the ability of infected cells to fuse%3B Serpin 1%2C2%2C3%3B similar to VACV-WR C2L and VACV-Cop K2L;gbkey=CDS;gene=OPG040;locus_tag=NBT03_gp021;product=Serpin;protein_id=YP_010377023.1 +NC_063383.1 RefSeq sequence_feature 25529 25767 . - . ID=id-NC_063383.1:25529..25767;exon_number=OPG041;gbkey=misc_feature;number=OPG041 +NC_063383.1 RefSeq gene 25823 27097 . - . ID=gene-NBT03_gp022;Dbxref=GeneID:72551438;Name=OPG042;gbkey=Gene;gene=OPG042;gene_biotype=protein_coding;locus_tag=NBT03_gp022;old_locus_tag=MPXV-M5312_HM12_Rivers-026 +NC_063383.1 RefSeq CDS 25823 27097 . - 0 ID=cds-YP_010377025.1;Parent=gene-NBT03_gp022;Dbxref=GenBank:YP_010377025.1,GeneID:72551438;Name=OPG042;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp030%3B phospholipase D-like%3B Phospholipase-D-like protein%3B similar to VACV-WR C4L and VACV-Cop K4L;gbkey=CDS;gene=OPG042;locus_tag=NBT03_gp022;product=Phospholipase-D-like protein;protein_id=YP_010377025.1 +NC_063383.1 RefSeq gene 27125 27955 . - . ID=gene-NBT03_gp023;Dbxref=GeneID:72551439;Name=OPG043;gbkey=Gene;gene=OPG043;gene_biotype=protein_coding;locus_tag=NBT03_gp023;old_locus_tag=MPXV-M5312_HM12_Rivers-027 +NC_063383.1 RefSeq CDS 27125 27955 . - 0 ID=cds-YP_010377026.1;Parent=gene-NBT03_gp023;Dbxref=GenBank:YP_010377026.1,GeneID:72551439;Name=OPG043;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp031%3B lysophospholipase-like%3B Monoglyceride lipase%3B similar to VACV-WR C5L and VACV-Cop K5L;gbkey=CDS;gene=OPG043;locus_tag=NBT03_gp023;product=Putative monoglyceride lipase;protein_id=YP_010377026.1 +NC_063383.1 RefSeq gene 28091 28540 . + . ID=gene-NBT03_gp024;Dbxref=GeneID:72551440;Name=OPG044;gbkey=Gene;gene=OPG044;gene_biotype=protein_coding;locus_tag=NBT03_gp024;old_locus_tag=MPXV-M5312_HM12_Rivers-028 +NC_063383.1 RefSeq CDS 28091 28540 . + 0 ID=cds-YP_010377027.1;Parent=gene-NBT03_gp024;Dbxref=GenBank:YP_010377027.1,GeneID:72551440;Name=OPG044;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp032%3B Putative tlr signaling inhibitor%3B Host immune response repressor%3B similar to VACV-WR C6R and VACV-Cop #K7R;gbkey=CDS;gene=OPG044;locus_tag=NBT03_gp024;product=Bcl-2-like protein;protein_id=YP_010377027.1 +NC_063383.1 RefSeq gene 28603 29262 . - . ID=gene-NBT03_gp025;Dbxref=GeneID:72551441;Name=OPG045;gbkey=Gene;gene=OPG045;gene_biotype=protein_coding;locus_tag=NBT03_gp025;old_locus_tag=MPXV-M5312_HM12_Rivers-029 +NC_063383.1 RefSeq CDS 28603 29262 . - 0 ID=cds-YP_010377028.1;Parent=gene-NBT03_gp025;Dbxref=GenBank:YP_010377028.1,GeneID:72551441;Name=OPG045;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp033%3B Caspase-9 (apoptosis) inhibitor (mitochondrial- associated)%3B similar to VACV-WR C7L and VACV-Cop F1L;gbkey=CDS;gene=OPG045;locus_tag=NBT03_gp025;product=Caspase-9 inhibitor;protein_id=YP_010377028.1 +NC_063383.1 RefSeq gene 29274 29729 . - . ID=gene-NBT03_gp026;Dbxref=GeneID:72551442;Name=OPG046;gbkey=Gene;gene=OPG046;gene_biotype=protein_coding;locus_tag=NBT03_gp026;old_locus_tag=MPXV-M5312_HM12_Rivers-030 +NC_063383.1 RefSeq CDS 29274 29729 . - 0 ID=cds-YP_010377029.1;Parent=gene-NBT03_gp026;Dbxref=GenBank:YP_010377029.1,GeneID:72551442;Name=OPG046;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp034%3B deoxyuridine triphosphatase%3B dUTPase%3B similar to VACV-WR C8L and VACV-Cop F2L;gbkey=CDS;gene=OPG046;locus_tag=NBT03_gp026;product=dUTPase;protein_id=YP_010377029.1 +NC_063383.1 RefSeq gene 29746 31194 . - . ID=gene-NBT03_gp027;Dbxref=GeneID:72551443;Name=OPG047;gbkey=Gene;gene=OPG047;gene_biotype=protein_coding;locus_tag=NBT03_gp027;old_locus_tag=MPXV-M5312_HM12_Rivers-031 +NC_063383.1 RefSeq CDS 29746 31194 . - 0 ID=cds-YP_010377030.1;Parent=gene-NBT03_gp027;Dbxref=GenBank:YP_010377030.1,GeneID:72551443;Name=OPG047;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp035%3B kelch-like%3B Kelch-like protein%3B similar to VACV-WR C9L and VACV-Cop F3L;gbkey=CDS;gene=OPG047;locus_tag=NBT03_gp027;product=Kelch-like protein (2);protein_id=YP_010377030.1 +NC_063383.1 RefSeq gene 31205 32164 . - . ID=gene-NBT03_gp028;Dbxref=GeneID:72551444;Name=OPG048;gbkey=Gene;gene=OPG048;gene_biotype=protein_coding;locus_tag=NBT03_gp028;old_locus_tag=MPXV-M5312_HM12_Rivers-032 +NC_063383.1 RefSeq CDS 31205 32164 . - 0 ID=cds-YP_010377031.1;Parent=gene-NBT03_gp028;Dbxref=GenBank:YP_010377031.1,GeneID:72551444;Name=OPG048;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp036%3B Ribonucleotide reductase small subunit%2C R2%3B similar to VACV-WR C10L and VACV-Cop F4L;gbkey=CDS;gene=OPG048;locus_tag=NBT03_gp028;product=Ribonucleotide reductase small subunit;protein_id=YP_010377031.1 +NC_063383.1 RefSeq gene 32195 33151 . - . ID=gene-NBT03_gp029;Dbxref=GeneID:72551445;Name=OPG049;gbkey=Gene;gene=OPG049;gene_biotype=protein_coding;locus_tag=NBT03_gp029;old_locus_tag=MPXV-M5312_HM12_Rivers-033 +NC_063383.1 RefSeq CDS 32195 33151 . - 0 ID=cds-YP_010377032.1;Parent=gene-NBT03_gp029;Dbxref=GenBank:YP_010377032.1,GeneID:72551445;Name=OPG049;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp037%3B 36kDa major membrane protein%3B similar to VACV-WR C11L and VACV-Cop F5L;gbkey=CDS;gene=OPG049;locus_tag=NBT03_gp029;product=Telomere-binding protein I6 (1);protein_id=YP_010377032.1 +NC_063383.1 RefSeq gene 33181 33408 . - . ID=gene-NBT03_gp030;Dbxref=GeneID:72551446;Name=OPG050;gbkey=Gene;gene=OPG050;gene_biotype=protein_coding;locus_tag=NBT03_gp030;old_locus_tag=MPXV-M5312_HM12_Rivers-034 +NC_063383.1 RefSeq CDS 33181 33408 . - 0 ID=cds-YP_010377033.1;Parent=gene-NBT03_gp030;Dbxref=GenBank:YP_010377033.1,GeneID:72551446;Name=OPG050;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp038%3B Hypothetical protein%3B similar to VACV-WR C12L and VACV-Cop F6L;gbkey=CDS;gene=OPG050;locus_tag=NBT03_gp030;product=CPXV053 protein;protein_id=YP_010377033.1 +NC_063383.1 RefSeq gene 33425 33649 . - . ID=gene-NBT03_gp031;Dbxref=GeneID:72551447;Name=OPG051;gbkey=Gene;gene=OPG051;gene_biotype=protein_coding;locus_tag=NBT03_gp031;old_locus_tag=MPXV-M5312_HM12_Rivers-035 +NC_063383.1 RefSeq CDS 33425 33649 . - 0 ID=cds-YP_010377034.1;Parent=gene-NBT03_gp031;Dbxref=GenBank:YP_010377034.1,GeneID:72551447;Name=OPG051;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp039%3B Hypothetical protein%3B similar to VACV-WR C13L and VACV-Cop F7L;gbkey=CDS;gene=OPG051;locus_tag=NBT03_gp031;product=CPXV054 protein;protein_id=YP_010377034.1 +NC_063383.1 RefSeq gene 33801 33995 . - . ID=gene-NBT03_gp032;Dbxref=GeneID:72551448;Name=OPG052;gbkey=Gene;gene=OPG052;gene_biotype=protein_coding;locus_tag=NBT03_gp032;old_locus_tag=MPXV-M5312_HM12_Rivers-036 +NC_063383.1 RefSeq CDS 33801 33995 . - 0 ID=cds-YP_010377035.1;Parent=gene-NBT03_gp032;Dbxref=GenBank:YP_010377035.1,GeneID:72551448;Name=OPG052;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp040%3B Cytoplasmic protein%3B similar to VACV-WR C14L and VACV-Cop F8L;gbkey=CDS;gene=OPG052;locus_tag=NBT03_gp032;product=Cytoplasmic protein;protein_id=YP_010377035.1 +NC_063383.1 RefSeq gene 34052 34690 . - . ID=gene-NBT03_gp033;Dbxref=GeneID:72551449;Name=OPG053;gbkey=Gene;gene=OPG053;gene_biotype=protein_coding;locus_tag=NBT03_gp033;old_locus_tag=MPXV-M5312_HM12_Rivers-037 +NC_063383.1 RefSeq CDS 34052 34690 . - 0 ID=cds-YP_010377036.1;Parent=gene-NBT03_gp033;Dbxref=GenBank:YP_010377036.1,GeneID:72551449;Name=OPG053;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp041%3B S-S bond formation pathway protein substrate%3B similar to VACV-WR C15L and VACV-Cop F9L;gbkey=CDS;gene=OPG053;locus_tag=NBT03_gp033;product=IMV membrane protein L1R;protein_id=YP_010377036.1 +NC_063383.1 RefSeq gene 34677 35996 . - . ID=gene-NBT03_gp034;Dbxref=GeneID:72551450;Name=OPG054;gbkey=Gene;gene=OPG054;gene_biotype=protein_coding;locus_tag=NBT03_gp034;old_locus_tag=MPXV-M5312_HM12_Rivers-038 +NC_063383.1 RefSeq CDS 34677 35996 . - 0 ID=cds-YP_010377037.1;Parent=gene-NBT03_gp034;Dbxref=GenBank:YP_010377037.1,GeneID:72551450;Name=OPG054;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp042%3B serine%3B Essential Ser/Thr kinase morph%3B similar to VACV-WR C16L and VACV-Cop F10L;gbkey=CDS;gene=OPG054;locus_tag=NBT03_gp034;product=Serine/threonine-protein kinase;protein_id=YP_010377037.1 +NC_063383.1 RefSeq gene 36019 37083 . - . ID=gene-NBT03_gp035;Dbxref=GeneID:72551451;Name=OPG055;gbkey=Gene;gene=OPG055;gene_biotype=protein_coding;locus_tag=NBT03_gp035;old_locus_tag=MPXV-M5312_HM12_Rivers-039 +NC_063383.1 RefSeq CDS 36019 37083 . - 0 ID=cds-YP_010377038.1;Parent=gene-NBT03_gp035;Dbxref=GenBank:YP_010377038.1,GeneID:72551451;Name=OPG055;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp043%3B RhoA signalling inhibitor%2C virus release protein%3B MC018%3B similar to VACV-WR C17L and VACV-Cop F11L;gbkey=CDS;gene=OPG055;locus_tag=NBT03_gp035;product=Protein F11;protein_id=YP_010377038.1 +NC_063383.1 RefSeq gene 37127 39034 . - . ID=gene-NBT03_gp036;Dbxref=GeneID:72551452;Name=OPG056;gbkey=Gene;gene=OPG056;gene_biotype=protein_coding;locus_tag=NBT03_gp036;old_locus_tag=MPXV-M5312_HM12_Rivers-040 +NC_063383.1 RefSeq CDS 37127 39034 . - 0 ID=cds-YP_010377039.1;Parent=gene-NBT03_gp036;Dbxref=GenBank:YP_010377039.1,GeneID:72551452;Name=OPG056;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp044%3B actin tail formation%3B EEV maturation protein%3B similar to VACV-WR C18L and VACV-Cop F12L;gbkey=CDS;gene=OPG056;locus_tag=NBT03_gp036;product=EEV maturation protein;protein_id=YP_010377039.1 +NC_063383.1 RefSeq gene 39077 40195 . - . ID=gene-NBT03_gp037;Dbxref=GeneID:72551453;Name=OPG057;gbkey=Gene;gene=OPG057;gene_biotype=protein_coding;locus_tag=NBT03_gp037;old_locus_tag=MPXV-M5312_HM12_Rivers-041 +NC_063383.1 RefSeq CDS 39077 40195 . - 0 ID=cds-YP_010377040.1;Parent=gene-NBT03_gp037;Dbxref=GenBank:YP_010377040.1,GeneID:72551453;Name=OPG057;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp045%3B major envelope antigen of EEV%3B wrapping of IMV to form IEV%3B phospholipase D-like%3B Palmitylated EEV membrane glycoprotein%3B similar to VACV-WR C19L and VACV-Cop F13L;gbkey=CDS;gene=OPG057;locus_tag=NBT03_gp037;product=Palmytilated EEV membrane protein;protein_id=YP_010377040.1 +NC_063383.1 RefSeq gene 40213 40434 . - . ID=gene-NBT03_gp038;Dbxref=GeneID:72551454;Name=OPG058;gbkey=Gene;gene=OPG058;gene_biotype=protein_coding;locus_tag=NBT03_gp038;old_locus_tag=MPXV-M5312_HM12_Rivers-042 +NC_063383.1 RefSeq CDS 40213 40434 . - 0 ID=cds-YP_010377041.1;Parent=gene-NBT03_gp038;Dbxref=GenBank:YP_010377041.1,GeneID:72551454;Name=OPG058;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp046%3B similar to VACV-WR C20L and VACV-Cop F14L;gbkey=CDS;gene=OPG058;locus_tag=NBT03_gp038;product=Protein F14 (1);protein_id=YP_010377041.1 +NC_063383.1 RefSeq gene 40484 40633 . - . ID=gene-NBT03_gp039;Dbxref=GeneID:72551455;Name=OPG059;gbkey=Gene;gene=OPG059;gene_biotype=protein_coding;locus_tag=NBT03_gp039;old_locus_tag=MPXV-M5312_HM12_Rivers-043 +NC_063383.1 RefSeq CDS 40484 40633 . - 0 ID=cds-YP_010377042.1;Parent=gene-NBT03_gp039;Dbxref=GenBank:YP_010377042.1,GeneID:72551455;Name=OPG059;Note=Taxonomic breadth: poxvirinae%3B IMV protein%3B C20.5L%3B similar to VACV-CopF14.5L;gbkey=CDS;gene=OPG059;locus_tag=NBT03_gp039;product=Cytochrome C oxidase;protein_id=YP_010377042.1 +NC_063383.1 RefSeq gene 40706 41182 . - . ID=gene-NBT03_gp040;Dbxref=GeneID:72551456;Name=OPG060;gbkey=Gene;gene=OPG060;gene_biotype=protein_coding;locus_tag=NBT03_gp040;old_locus_tag=MPXV-M5312_HM12_Rivers-044 +NC_063383.1 RefSeq CDS 40706 41182 . - 0 ID=cds-YP_010377043.1;Parent=gene-NBT03_gp040;Dbxref=GenBank:YP_010377043.1,GeneID:72551456;Name=OPG060;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp047%3B Unknown conserved protein%3B similar to VACV-WR C21L and VACV-Cop F15L;gbkey=CDS;gene=OPG060;locus_tag=NBT03_gp040;product=Protein F15;protein_id=YP_010377043.1 +NC_063383.1 RefSeq gene 41189 41884 . - . ID=gene-NBT03_gp041;Dbxref=GeneID:72551457;Name=OPG061;gbkey=Gene;gene=OPG061;gene_biotype=protein_coding;locus_tag=NBT03_gp041;old_locus_tag=MPXV-M5312_HM12_Rivers-045 +NC_063383.1 RefSeq CDS 41189 41884 . - 0 ID=cds-YP_010377044.1;Parent=gene-NBT03_gp041;Dbxref=GenBank:YP_010377044.1,GeneID:72551457;Name=OPG061;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp048%3B Non-functional Serine Recombinase%3B similar to VACV-WR C22L and VACV-Cop F16L;gbkey=CDS;gene=OPG061;locus_tag=NBT03_gp041;product=Protein F16 (1);protein_id=YP_010377044.1 +NC_063383.1 RefSeq gene 41947 42252 . + . ID=gene-NBT03_gp042;Dbxref=GeneID:72551458;Name=OPG062;gbkey=Gene;gene=OPG062;gene_biotype=protein_coding;locus_tag=NBT03_gp042;old_locus_tag=MPXV-M5312_HM12_Rivers-046 +NC_063383.1 RefSeq CDS 41947 42252 . + 0 ID=cds-YP_010377045.1;Parent=gene-NBT03_gp042;Dbxref=GenBank:YP_010377045.1,GeneID:72551458;Name=OPG062;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp049%3B virion core DNA-binding phosphoprotein (VP11)%3B mTOR antagonist%3B similar to VACV-WR C23R and VACV-Cop F17R;gbkey=CDS;gene=OPG062;locus_tag=NBT03_gp042;product=DNA-binding phosphoprotein (1);protein_id=YP_010377045.1 +NC_063383.1 RefSeq gene 42249 43688 . - . ID=gene-NBT03_gp043;Dbxref=GeneID:72551459;Name=OPG063;gbkey=Gene;gene=OPG063;gene_biotype=protein_coding;locus_tag=NBT03_gp043;old_locus_tag=MPXV-M5312_HM12_Rivers-047 +NC_063383.1 RefSeq CDS 42249 43688 . - 0 ID=cds-YP_010377046.1;Parent=gene-NBT03_gp043;Dbxref=GenBank:YP_010377046.1,GeneID:72551459;Name=OPG063;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp050%3B poly-A polymerase%2C Poly (A) polymerase catalytic subunit (VP55)%3B similar to VACV-WR F1L and VACV-Cop E1L;gbkey=CDS;gene=OPG063;locus_tag=NBT03_gp043;product=Poly(A) polymerase catalytic subunit (3);protein_id=YP_010377046.1 +NC_063383.1 RefSeq gene 43685 45898 . - . ID=gene-NBT03_gp044;Dbxref=GeneID:72551460;Name=OPG064;gbkey=Gene;gene=OPG064;gene_biotype=protein_coding;locus_tag=NBT03_gp044;old_locus_tag=MPXV-M5312_HM12_Rivers-048 +NC_063383.1 RefSeq CDS 43685 45898 . - 0 ID=cds-YP_010377047.1;Parent=gene-NBT03_gp044;Dbxref=GenBank:YP_010377047.1,GeneID:72551460;Name=OPG064;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp051%3B IEV morphogenesis%3B similar to VACV-WR F2L and VACV-Cop E2L;gbkey=CDS;gene=OPG064;locus_tag=NBT03_gp044;product=Iev morphogenesis protein;protein_id=YP_010377047.1 +NC_063383.1 RefSeq gene 46022 46483 . - . ID=gene-NBT03_gp045;Dbxref=GeneID:72551461;Name=OPG065;gbkey=Gene;gene=OPG065;gene_biotype=protein_coding;locus_tag=NBT03_gp045;old_locus_tag=MPXV-M5312_HM12_Rivers-049 +NC_063383.1 RefSeq CDS 46022 46483 . - 0 ID=cds-YP_010377048.1;Parent=gene-NBT03_gp045;Dbxref=GenBank:YP_010377048.1,GeneID:72551461;Name=OPG065;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp052%3B interferon resistance factor%3B two forms (25 kDa and 19 kDa) of the dsRNA-binding protein%3B inhibition of dsRNA-dependent protein kinase and 2-5A-synthet%3B dsRNA-binding protein%2C IFN resistance/PKR inhibitor (Z-DNA binding)%3B start of ORF is missing approx. 37 AA compared to CPXVs%3B similar to VACV-WR F3L and VACV-Cop E3L;gbkey=CDS;gene=OPG065;locus_tag=NBT03_gp045;product=Double-stranded RNA binding protein;protein_id=YP_010377048.1 +NC_063383.1 RefSeq gene 46649 47428 . - . ID=gene-NBT03_gp046;Dbxref=GeneID:72551462;Name=OPG066;gbkey=Gene;gene=OPG066;gene_biotype=protein_coding;locus_tag=NBT03_gp046;old_locus_tag=MPXV-M5312_HM12_Rivers-050 +NC_063383.1 RefSeq CDS 46649 47428 . - 0 ID=cds-YP_010377049.1;Parent=gene-NBT03_gp046;Dbxref=GenBank:YP_010377049.1,GeneID:72551462;Name=OPG066;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp053%3B RNA polymerase 30 kDa subunit (RPO30)%3B simultaneously intermediate stage promoter-specific transcription factor%2C VITF-1%3B similar to VACV-WR F4L and VACV-Cop E4L;gbkey=CDS;gene=OPG066;locus_tag=NBT03_gp046;product=DNA-directed RNA polymerase 30 kDa polypeptide;protein_id=YP_010377049.1 +NC_063383.1 RefSeq sequence_feature 47525 48062 . + . ID=id-NC_063383.1:47525..48062;exon_number=OPG067;gbkey=misc_feature;number=OPG067 +NC_063383.1 RefSeq gene 48201 49904 . + . ID=gene-NBT03_gp047;Dbxref=GeneID:72551463;Name=OPG068;gbkey=Gene;gene=OPG068;gene_biotype=protein_coding;locus_tag=NBT03_gp047;old_locus_tag=MPXV-M5312_HM12_Rivers-052 +NC_063383.1 RefSeq CDS 48201 49904 . + 0 ID=cds-YP_010377051.1;Parent=gene-NBT03_gp047;Dbxref=GenBank:YP_010377051.1,GeneID:72551463;Name=OPG068;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp054%3B Virion protein%3B similar to VACV-WR F5R and VACV-Cop E6R;gbkey=CDS;gene=OPG068;locus_tag=NBT03_gp047;product=IMV membrane protein E6;protein_id=YP_010377051.1 +NC_063383.1 RefSeq gene 49986 50486 . + . ID=gene-NBT03_gp048;Dbxref=GeneID:72551464;Name=OPG069;gbkey=Gene;gene=OPG069;gene_biotype=protein_coding;locus_tag=NBT03_gp048;old_locus_tag=MPXV-M5312_HM12_Rivers-053 +NC_063383.1 RefSeq CDS 49986 50486 . + 0 ID=cds-YP_010377052.1;Parent=gene-NBT03_gp048;Dbxref=GenBank:YP_010377052.1,GeneID:72551464;Name=OPG069;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp055%3B soluble myristylated protein%3B similar to VACV-WR F6R and VACV-Cop E7R;gbkey=CDS;gene=OPG069;locus_tag=NBT03_gp048;product=Myristoylated protein E7;protein_id=YP_010377052.1 +NC_063383.1 RefSeq gene 50590 51411 . + . ID=gene-NBT03_gp049;Dbxref=GeneID:72551465;Name=OPG070;gbkey=Gene;gene=OPG070;gene_biotype=protein_coding;locus_tag=NBT03_gp049;old_locus_tag=MPXV-M5312_HM12_Rivers-054 +NC_063383.1 RefSeq CDS 50590 51411 . + 0 ID=cds-YP_010377053.1;Parent=gene-NBT03_gp049;Dbxref=GenBank:YP_010377053.1,GeneID:72551465;Name=OPG070;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp056%3B ER-localized membrane protein%2C virion core protein%3B similar to VACV-WR F7R and VACV-Cop E8R;gbkey=CDS;gene=OPG070;locus_tag=NBT03_gp049;product=Membrane protein E8;protein_id=YP_010377053.1 +NC_063383.1 RefSeq gene 51418 54438 . - . ID=gene-NBT03_gp050;Dbxref=GeneID:72551466;Name=OPG071;gbkey=Gene;gene=OPG071;gene_biotype=protein_coding;locus_tag=NBT03_gp050;old_locus_tag=MPXV-M5312_HM12_Rivers-055 +NC_063383.1 RefSeq CDS 51418 54438 . - 0 ID=cds-YP_010377054.1;Parent=gene-NBT03_gp050;Dbxref=GenBank:YP_010377054.1,GeneID:72551466;Name=OPG071;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp057%3B DNA polymerase%2C catalytic subunit%3B similar to VACV-WR F8L and VACV-Cop E9L;gbkey=CDS;gene=OPG071;locus_tag=NBT03_gp050;product=DNA polymerase (2);protein_id=YP_010377054.1 +NC_063383.1 RefSeq gene 54470 54757 . + . ID=gene-NBT03_gp051;Dbxref=GeneID:72551467;Name=OPG072;gbkey=Gene;gene=OPG072;gene_biotype=protein_coding;locus_tag=NBT03_gp051;old_locus_tag=MPXV-M5312_HM12_Rivers-056 +NC_063383.1 RefSeq CDS 54470 54757 . + 0 ID=cds-YP_010377055.1;Parent=gene-NBT03_gp051;Dbxref=GenBank:YP_010377055.1,GeneID:72551467;Name=OPG072;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp058%3B protein disulfide bond-forming enzyme%3B Sulfhydryl oxidase (FAD-linked)%3B similar to VACV-WR F9R and VACV-Cop E10R;gbkey=CDS;gene=OPG072;locus_tag=NBT03_gp051;product=Sulfhydryl oxidase;protein_id=YP_010377055.1 +NC_063383.1 RefSeq gene 54752 55141 . - . ID=gene-NBT03_gp052;Dbxref=GeneID:72551468;Name=OPG073;gbkey=Gene;gene=OPG073;gene_biotype=protein_coding;locus_tag=NBT03_gp052;old_locus_tag=MPXV-M5312_HM12_Rivers-057 +NC_063383.1 RefSeq CDS 54752 55141 . - 0 ID=cds-YP_010377056.1;Parent=gene-NBT03_gp052;Dbxref=GenBank:YP_010377056.1,GeneID:72551468;Name=OPG073;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp059%3B virion core protein%3B similar to VACV-WR F10L and VACV-Cop E11L;gbkey=CDS;gene=OPG073;locus_tag=NBT03_gp052;product=Virion core protein E11;protein_id=YP_010377056.1 +NC_063383.1 RefSeq gene 55128 57125 . - . ID=gene-NBT03_gp053;Dbxref=GeneID:72551469;Name=OPG074;gbkey=Gene;gene=OPG074;gene_biotype=protein_coding;locus_tag=NBT03_gp053;old_locus_tag=MPXV-M5312_HM12_Rivers-058 +NC_063383.1 RefSeq CDS 55128 57125 . - 0 ID=cds-YP_010377057.1;Parent=gene-NBT03_gp053;Dbxref=GenBank:YP_010377057.1,GeneID:72551469;Name=OPG074;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp060%3B Membrane protein%3B similar to VACV-WR Q1L and VACV-Cop O1L;gbkey=CDS;gene=OPG074;locus_tag=NBT03_gp053;product=Iev morphogenesis protein;protein_id=YP_010377057.1 +NC_063383.1 RefSeq gene 57172 57498 . - . ID=gene-NBT03_gp054;Dbxref=GeneID:72551470;Name=OPG075;gbkey=Gene;gene=OPG075;gene_biotype=protein_coding;locus_tag=NBT03_gp054;old_locus_tag=MPXV-M5312_HM12_Rivers-059 +NC_063383.1 RefSeq CDS 57172 57498 . - 0 ID=cds-YP_010377058.1;Parent=gene-NBT03_gp054;Dbxref=GenBank:YP_010377058.1,GeneID:72551470;Name=OPG075;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp061%3B virion-associated glutaredoxin%3B glutaredoxin 1%3B similar to VACV-WR Q2L and VACV-Cop O2L;gbkey=CDS;gene=OPG075;locus_tag=NBT03_gp054;product=Glutaredoxin-1;protein_id=YP_010377058.1 +NC_063383.1 RefSeq gene 57523 57630 . - . ID=gene-NBT03_gp055;Dbxref=GeneID:72551471;Name=OPG076;gbkey=Gene;gene=OPG076;gene_biotype=protein_coding;locus_tag=NBT03_gp055 +NC_063383.1 RefSeq CDS 57523 57630 . - 0 ID=cds-YP_010377183.1;Parent=gene-NBT03_gp055;Dbxref=GenBank:YP_010377183.1,GeneID:72551471;Name=OPG076;gbkey=CDS;gene=OPG076;locus_tag=NBT03_gp055;product=MV membrane EFC component;protein_id=YP_010377183.1 +NC_063383.1 RefSeq gene 57645 58583 . - . ID=gene-NBT03_gp056;Dbxref=GeneID:72551472;Name=OPG077;gbkey=Gene;gene=OPG077;gene_biotype=protein_coding;locus_tag=NBT03_gp056;old_locus_tag=MPXV-M5312_HM12_Rivers-060 +NC_063383.1 RefSeq CDS 57645 58583 . - 0 ID=cds-YP_010377059.1;Parent=gene-NBT03_gp056;Dbxref=GenBank:YP_010377059.1,GeneID:72551472;Name=OPG077;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp062%3B virosomal protein essential for virus multiplication%3B DNA-binding core protein%3B similar to VACV-WR I1L and VACV-Cop I1L;gbkey=CDS;gene=OPG077;locus_tag=NBT03_gp056;product=Telomere-binding protein I1;protein_id=YP_010377059.1 +NC_063383.1 RefSeq gene 58590 58811 . - . ID=gene-NBT03_gp057;Dbxref=GeneID:72551473;Name=OPG078;gbkey=Gene;gene=OPG078;gene_biotype=protein_coding;locus_tag=NBT03_gp057;old_locus_tag=MPXV-M5312_HM12_Rivers-061 +NC_063383.1 RefSeq CDS 58590 58811 . - 0 ID=cds-YP_010377060.1;Parent=gene-NBT03_gp057;Dbxref=GenBank:YP_010377060.1,GeneID:72551473;Name=OPG078;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp063%3B IMV membrane protein%3B similar to VACV-WR I2L and VACV-Cop I2L;gbkey=CDS;gene=OPG078;locus_tag=NBT03_gp057;product=IMV membrane protein I2;protein_id=YP_010377060.1 +NC_063383.1 RefSeq gene 58812 59621 . - . ID=gene-NBT03_gp058;Dbxref=GeneID:72551474;Name=OPG079;gbkey=Gene;gene=OPG079;gene_biotype=protein_coding;locus_tag=NBT03_gp058;old_locus_tag=MPXV-M5312_HM12_Rivers-062 +NC_063383.1 RefSeq CDS 58812 59621 . - 0 ID=cds-YP_010377061.1;Parent=gene-NBT03_gp058;Dbxref=GenBank:YP_010377061.1,GeneID:72551474;Name=OPG079;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp064%3B virosomal ssDNA-binding phosphoprotein%3B interacts with R2 subunit of ribonucleotide reductase%3B similar to VACV-WR I3L and VACV-Cop I3L;gbkey=CDS;gene=OPG079;locus_tag=NBT03_gp058;product=DNA-binding phosphoprotein (2);protein_id=YP_010377061.1 +NC_063383.1 RefSeq gene 59703 62018 . - . ID=gene-NBT03_gp059;Dbxref=GeneID:72551475;Name=OPG080;gbkey=Gene;gene=OPG080;gene_biotype=protein_coding;locus_tag=NBT03_gp059;old_locus_tag=MPXV-M5312_HM12_Rivers-063 +NC_063383.1 RefSeq CDS 59703 62018 . - 0 ID=cds-YP_010377062.1;Parent=gene-NBT03_gp059;Dbxref=GenBank:YP_010377062.1,GeneID:72551475;Name=OPG080;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp065%3B ribonucleotide reductase%2C large subunit%2C R1%3B similar to VACV-WR I4L and VACV-Cop I4L;gbkey=CDS;gene=OPG080;locus_tag=NBT03_gp059;product=Ribonucleoside-diphosphate reductase (2);protein_id=YP_010377062.1 +NC_063383.1 RefSeq gene 62046 62285 . - . ID=gene-NBT03_gp060;Dbxref=GeneID:72551476;Name=OPG081;gbkey=Gene;gene=OPG081;gene_biotype=protein_coding;locus_tag=NBT03_gp060;old_locus_tag=MPXV-M5312_HM12_Rivers-064 +NC_063383.1 RefSeq CDS 62046 62285 . - 0 ID=cds-YP_010377063.1;Parent=gene-NBT03_gp060;Dbxref=GenBank:YP_010377063.1,GeneID:72551476;Name=OPG081;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp066%3B IMV surface membrane protein%2C VP13%3B similar to VACV-WR I5L and VACV-Cop I5L;gbkey=CDS;gene=OPG081;locus_tag=NBT03_gp060;product=IMV membrane protein I5;protein_id=YP_010377063.1 +NC_063383.1 RefSeq gene 62304 63452 . - . ID=gene-NBT03_gp061;Dbxref=GeneID:72551477;Name=OPG082;gbkey=Gene;gene=OPG082;gene_biotype=protein_coding;locus_tag=NBT03_gp061;old_locus_tag=MPXV-M5312_HM12_Rivers-065 +NC_063383.1 RefSeq CDS 62304 63452 . - 0 ID=cds-YP_010377064.1;Parent=gene-NBT03_gp061;Dbxref=GenBank:YP_010377064.1,GeneID:72551477;Name=OPG082;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp067%3B Telomere-binding protein%3B similar to VACV-WR I6L and VACV-Cop I6L;gbkey=CDS;gene=OPG082;locus_tag=NBT03_gp061;product=Telomere-binding protein;protein_id=YP_010377064.1 +NC_063383.1 RefSeq gene 63445 64716 . - . ID=gene-NBT03_gp062;Dbxref=GeneID:72551478;Name=OPG083;gbkey=Gene;gene=OPG083;gene_biotype=protein_coding;locus_tag=NBT03_gp062;old_locus_tag=MPXV-M5312_HM12_Rivers-066 +NC_063383.1 RefSeq CDS 63445 64716 . - 0 ID=cds-YP_010377065.1;Parent=gene-NBT03_gp062;Dbxref=GenBank:YP_010377065.1,GeneID:72551478;Name=OPG083;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp068%3B virion core protein%3B similar to DNA topoisomerase II%3B Virion core cysteine protease%3B similar to VACV-WR I7L and VACV-Cop I7L;gbkey=CDS;gene=OPG083;locus_tag=NBT03_gp062;product=Viral core cysteine proteinase;protein_id=YP_010377065.1 +NC_063383.1 RefSeq gene 64722 66752 . + . ID=gene-NBT03_gp063;Dbxref=GeneID:72551479;Name=OPG084;gbkey=Gene;gene=OPG084;gene_biotype=protein_coding;locus_tag=NBT03_gp063;old_locus_tag=MPXV-M5312_HM12_Rivers-067 +NC_063383.1 RefSeq CDS 64722 66752 . + 0 ID=cds-YP_010377066.1;Parent=gene-NBT03_gp063;Dbxref=GenBank:YP_010377066.1,GeneID:72551479;Name=OPG084;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp069%3B nucleoside triphosphate phosphohydrolase II%2C NPH-II%3B DNA and RNA helicase%3B DExH-NPH-II domain%3B similar to VACV-WR I8R and VACV-Cop I8R;gbkey=CDS;gene=OPG084;locus_tag=NBT03_gp063;product=RNA helicase NPH-II (2);protein_id=YP_010377066.1 +NC_063383.1 RefSeq gene 66756 68531 . - . ID=gene-NBT03_gp064;Dbxref=GeneID:72551480;Name=OPG085;gbkey=Gene;gene=OPG085;gene_biotype=protein_coding;locus_tag=NBT03_gp064;old_locus_tag=MPXV-M5312_HM12_Rivers-068 +NC_063383.1 RefSeq CDS 66756 68531 . - 0 ID=cds-YP_010377067.1;Parent=gene-NBT03_gp064;Dbxref=GenBank:YP_010377067.1,GeneID:72551480;Name=OPG085;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp070%3B proteinase%3B Metalloprotease%3B similar to VACV-WR G1L and VACV-Cop G1L;gbkey=CDS;gene=OPG085;locus_tag=NBT03_gp064;product=Metalloendopeptidase;protein_id=YP_010377067.1 +NC_063383.1 RefSeq gene 68528 68863 . - . ID=gene-NBT03_gp065;Dbxref=GeneID:72551481;Name=OPG086;gbkey=Gene;gene=OPG086;gene_biotype=protein_coding;locus_tag=NBT03_gp065;old_locus_tag=MPXV-M5312_HM12_Rivers-069 +NC_063383.1 RefSeq CDS 68528 68863 . - 0 ID=cds-YP_010377068.1;Parent=gene-NBT03_gp065;Dbxref=GenBank:YP_010377068.1,GeneID:72551481;Name=OPG086;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp071%3B Entry/fusion complex component%3B similar to VACV-WR G2L and VACV-Cop G3L;gbkey=CDS;gene=OPG086;locus_tag=NBT03_gp065;product=Entry/fusion complex component;protein_id=YP_010377068.1 +NC_063383.1 RefSeq gene 68857 69519 . + . ID=gene-NBT03_gp066;Dbxref=GeneID:72551482;Name=OPG087;gbkey=Gene;gene=OPG087;gene_biotype=protein_coding;locus_tag=NBT03_gp066;old_locus_tag=MPXV-M5312_HM12_Rivers-070 +NC_063383.1 RefSeq CDS 68857 69519 . + 0 ID=cds-YP_010377069.1;Parent=gene-NBT03_gp066;Dbxref=GenBank:YP_010377069.1,GeneID:72551482;Name=OPG087;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp072%3B VLTF (late transcription elongation factor)%3B similar to VACV-WR G3R and VACV-Cop G2R;gbkey=CDS;gene=OPG087;locus_tag=NBT03_gp066;product=Late transcription elongation factor;protein_id=YP_010377069.1 +NC_063383.1 RefSeq gene 69489 69863 . - . ID=gene-NBT03_gp067;Dbxref=GeneID:72551483;Name=OPG088;gbkey=Gene;gene=OPG088;gene_biotype=protein_coding;locus_tag=NBT03_gp067;old_locus_tag=MPXV-M5312_HM12_Rivers-071 +NC_063383.1 RefSeq CDS 69489 69863 . - 0 ID=cds-YP_010377070.1;Parent=gene-NBT03_gp067;Dbxref=GenBank:YP_010377070.1,GeneID:72551483;Name=OPG088;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp073%3B virion-associated glutaredoxin%3B Glutaredoxin-like protein%3B similar to VACV-WR G4L and VACV-Cop G4L;gbkey=CDS;gene=OPG088;locus_tag=NBT03_gp067;product=Glutaredoxin-2;protein_id=YP_010377070.1 +NC_063383.1 RefSeq gene 69866 71170 . + . ID=gene-NBT03_gp068;Dbxref=GeneID:72551484;Name=OPG089;gbkey=Gene;gene=OPG089;gene_biotype=protein_coding;locus_tag=NBT03_gp068;old_locus_tag=MPXV-M5312_HM12_Rivers-072 +NC_063383.1 RefSeq CDS 69866 71170 . + 0 ID=cds-YP_010377071.1;Parent=gene-NBT03_gp068;Dbxref=GenBank:YP_010377071.1,GeneID:72551484;Name=OPG089;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp074%3B FEN1-like nuclease%3B similar to VACV-WR G5R and VACV-Cop G5R;gbkey=CDS;gene=OPG089;locus_tag=NBT03_gp068;product=FEN1-like nuclease;protein_id=YP_010377071.1 +NC_063383.1 RefSeq gene 71179 71370 . + . ID=gene-NBT03_gp069;Dbxref=GeneID:72551485;Name=OPG090;gbkey=Gene;gene=OPG090;gene_biotype=protein_coding;locus_tag=NBT03_gp069;old_locus_tag=MPXV-M5312_HM12_Rivers-073 +NC_063383.1 RefSeq CDS 71179 71370 . + 0 ID=cds-YP_010377072.1;Parent=gene-NBT03_gp069;Dbxref=GenBank:YP_010377072.1,GeneID:72551485;Name=OPG090;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp075%3B RNA polymerase subunit%2C 7 kDa subunit (RPO7)%3B similar to VACV-WR G6R and VACV-Cop G5.5R;gbkey=CDS;gene=OPG090;locus_tag=NBT03_gp069;product=DNA-directed RNA polymerase 7 kDa subunit;protein_id=YP_010377072.1 +NC_063383.1 RefSeq gene 71370 71867 . + . ID=gene-NBT03_gp070;Dbxref=GeneID:72551486;Name=OPG091;gbkey=Gene;gene=OPG091;gene_biotype=protein_coding;locus_tag=NBT03_gp070;old_locus_tag=MPXV-M5312_HM12_Rivers-074 +NC_063383.1 RefSeq CDS 71370 71867 . + 0 ID=cds-YP_010377073.1;Parent=gene-NBT03_gp070;Dbxref=GenBank:YP_010377073.1,GeneID:72551486;Name=OPG091;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp076%3B NLPc/P60 superfamily protein%3B similar to VACV-WR G7R and VACV-Cop G6R;gbkey=CDS;gene=OPG091;locus_tag=NBT03_gp070;product=Nlpc/p60 superfamily protein;protein_id=YP_010377073.1 +NC_063383.1 RefSeq gene 71832 72947 . - . ID=gene-NBT03_gp071;Dbxref=GeneID:72551487;Name=OPG092;gbkey=Gene;gene=OPG092;gene_biotype=protein_coding;locus_tag=NBT03_gp071;old_locus_tag=MPXV-M5312_HM12_Rivers-075 +NC_063383.1 RefSeq CDS 71832 72947 . - 0 ID=cds-YP_010377074.1;Parent=gene-NBT03_gp071;Dbxref=GenBank:YP_010377074.1,GeneID:72551487;Name=OPG092;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp077%3B virion protein%3B Virion phosphoprotein%2C early morphogenesis%3B similar to VACV-WR G8L and VACV-Cop G7L;gbkey=CDS;gene=OPG092;locus_tag=NBT03_gp071;product=Assembly protein G7;protein_id=YP_010377074.1 +NC_063383.1 RefSeq gene 72978 73760 . + . ID=gene-NBT03_gp072;Dbxref=GeneID:72551488;Name=OPG093;gbkey=Gene;gene=OPG093;gene_biotype=protein_coding;locus_tag=NBT03_gp072;old_locus_tag=MPXV-M5312_HM12_Rivers-076 +NC_063383.1 RefSeq CDS 72978 73760 . + 0 ID=cds-YP_010377075.1;Parent=gene-NBT03_gp072;Dbxref=GenBank:YP_010377075.1,GeneID:72551488;Name=OPG093;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp078%3B late gene transcription factor%2C VLTF-1%3B similar to VACV-WR G9R and VACV-Cop G8R;gbkey=CDS;gene=OPG093;locus_tag=NBT03_gp072;product=Late transcription factor VLTF-1;protein_id=YP_010377075.1 +NC_063383.1 RefSeq gene 73780 74802 . + . ID=gene-NBT03_gp073;Dbxref=GeneID:72551489;Name=OPG094;gbkey=Gene;gene=OPG094;gene_biotype=protein_coding;locus_tag=NBT03_gp073;old_locus_tag=MPXV-M5312_HM12_Rivers-077 +NC_063383.1 RefSeq CDS 73780 74802 . + 0 ID=cds-YP_010377076.1;Parent=gene-NBT03_gp073;Dbxref=GenBank:YP_010377076.1,GeneID:72551489;Name=OPG094;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp079%3B myristylated protein%3B Entry/fusion complex component%2C myristylprotein%3B similar to VACV-WR G10R and VACV-Cop G9R;gbkey=CDS;gene=OPG094;locus_tag=NBT03_gp073;product=Myristylated protein;protein_id=YP_010377076.1 +NC_063383.1 RefSeq gene 74803 75555 . + . ID=gene-NBT03_gp074;Dbxref=GeneID:72551490;Name=OPG095;gbkey=Gene;gene=OPG095;gene_biotype=protein_coding;locus_tag=NBT03_gp074;old_locus_tag=MPXV-M5312_HM12_Rivers-078 +NC_063383.1 RefSeq CDS 74803 75555 . + 0 ID=cds-YP_010377077.1;Parent=gene-NBT03_gp074;Dbxref=GenBank:YP_010377077.1,GeneID:72551490;Name=OPG095;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp080%3B myristylated IMV surface membrane protein%3B similar to VACV-WR M1R and VACV-Cop L1R;gbkey=CDS;gene=OPG095;locus_tag=NBT03_gp074;product=IMV membrane protein L1R;protein_id=YP_010377077.1 +NC_063383.1 RefSeq gene 75587 75865 . + . ID=gene-NBT03_gp075;Dbxref=GeneID:72551491;Name=OPG096;gbkey=Gene;gene=OPG096;gene_biotype=protein_coding;locus_tag=NBT03_gp075;old_locus_tag=MPXV-M5312_HM12_Rivers-079 +NC_063383.1 RefSeq CDS 75587 75865 . + 0 ID=cds-YP_010377078.1;Parent=gene-NBT03_gp075;Dbxref=GenBank:YP_010377078.1,GeneID:72551491;Name=OPG096;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp081%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR M2R and VACV-Cop L2R;gbkey=CDS;gene=OPG096;locus_tag=NBT03_gp075;product=Crescent membrane and immature virion formation protein;protein_id=YP_010377078.1 +NC_063383.1 RefSeq gene 75841 76875 . - . ID=gene-NBT03_gp076;Dbxref=GeneID:72551492;Name=OPG097;gbkey=Gene;gene=OPG097;gene_biotype=protein_coding;locus_tag=NBT03_gp076;old_locus_tag=MPXV-M5312_HM12_Rivers-080 +NC_063383.1 RefSeq CDS 75841 76875 . - 0 ID=cds-YP_010377079.1;Parent=gene-NBT03_gp076;Dbxref=GenBank:YP_010377079.1,GeneID:72551492;Name=OPG097;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp082%3B Internal virion protein%3B similar to VACV-WR M3L and VACV-Cop L3L;gbkey=CDS;gene=OPG097;locus_tag=NBT03_gp076;product=Internal virion L3/FP4 protein;protein_id=YP_010377079.1 +NC_063383.1 RefSeq gene 76900 77655 . + . ID=gene-NBT03_gp077;Dbxref=GeneID:72551493;Name=OPG098;gbkey=Gene;gene=OPG098;gene_biotype=protein_coding;locus_tag=NBT03_gp077;old_locus_tag=MPXV-M5312_HM12_Rivers-081 +NC_063383.1 RefSeq CDS 76900 77655 . + 0 ID=cds-YP_010377080.1;Parent=gene-NBT03_gp077;Dbxref=GenBank:YP_010377080.1,GeneID:72551493;Name=OPG098;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp083%3B virion core protein vp8%3B stimulation of I8R helicase activity%3B ss/dsDNA binding protein (VP8)%3B similar to VACV-WR M4R and VACV-Cop L4R;gbkey=CDS;gene=OPG098;locus_tag=NBT03_gp077;product=Nucleic acid binding protein VP8/L4R;protein_id=YP_010377080.1 +NC_063383.1 RefSeq gene 77665 78051 . + . ID=gene-NBT03_gp078;Dbxref=GeneID:72551494;Name=OPG099;gbkey=Gene;gene=OPG099;gene_biotype=protein_coding;locus_tag=NBT03_gp078;old_locus_tag=MPXV-M5312_HM12_Rivers-082 +NC_063383.1 RefSeq CDS 77665 78051 . + 0 ID=cds-YP_010377081.1;Parent=gene-NBT03_gp078;Dbxref=GenBank:YP_010377081.1,GeneID:72551494;Name=OPG099;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp084%3B Entry and Fusion IMV protein%3B similar to VACV-WR M5R and VACV-Cop L5R;gbkey=CDS;gene=OPG099;locus_tag=NBT03_gp078;product=Membrane protein CL5;protein_id=YP_010377081.1 +NC_063383.1 RefSeq gene 78008 78466 . + . ID=gene-NBT03_gp079;Dbxref=GeneID:72551495;Name=OPG100;gbkey=Gene;gene=OPG100;gene_biotype=protein_coding;locus_tag=NBT03_gp079;old_locus_tag=MPXV-M5312_HM12_Rivers-083 +NC_063383.1 RefSeq CDS 78008 78466 . + 0 ID=cds-YP_010377082.1;Parent=gene-NBT03_gp079;Dbxref=GenBank:YP_010377082.1,GeneID:72551495;Name=OPG100;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp085%3B Virion morph%3B similar to VACV-WR L1R and VACV-Cop J1R;gbkey=CDS;gene=OPG100;locus_tag=NBT03_gp079;product=IMV membrane protein J1;protein_id=YP_010377082.1 +NC_063383.1 RefSeq gene 78486 79019 . + . ID=gene-NBT03_gp080;Dbxref=GeneID:72551496;Name=OPG101;gbkey=Gene;gene=OPG101;gene_biotype=protein_coding;locus_tag=NBT03_gp080;old_locus_tag=MPXV-M5312_HM12_Rivers-084 +NC_063383.1 RefSeq CDS 78486 79019 . + 0 ID=cds-YP_010377083.1;Parent=gene-NBT03_gp080;Dbxref=GenBank:YP_010377083.1,GeneID:72551496;Name=OPG101;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp086%3B thymidine kinase%3B similar to VACV-WR L2R and VACV-Cop J2R;gbkey=CDS;gene=OPG101;locus_tag=NBT03_gp080;product=Thymidine kinase;protein_id=YP_010377083.1 +NC_063383.1 RefSeq gene 79085 80086 . + . ID=gene-NBT03_gp081;Dbxref=GeneID:72551497;Name=OPG102;gbkey=Gene;gene=OPG102;gene_biotype=protein_coding;locus_tag=NBT03_gp081;old_locus_tag=MPXV-M5312_HM12_Rivers-085 +NC_063383.1 RefSeq CDS 79085 80086 . + 0 ID=cds-YP_010377084.1;Parent=gene-NBT03_gp081;Dbxref=GenBank:YP_010377084.1,GeneID:72551497;Name=OPG102;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp087%3B poly-A polymerase%2C stimulatory subunit%2C simultaneously cap-specific mRNA (nucleoside-O2'-)-methyltransferase%3B Poly (A) polymerase small subunit (VP39)%3B similar to VACV-WR L3R and VACV-Cop J3R;gbkey=CDS;gene=OPG102;locus_tag=NBT03_gp081;product=Cap-specific mRNA;protein_id=YP_010377084.1 +NC_063383.1 RefSeq gene 80001 80558 . + . ID=gene-NBT03_gp082;Dbxref=GeneID:72551498;Name=OPG103;gbkey=Gene;gene=OPG103;gene_biotype=protein_coding;locus_tag=NBT03_gp082;old_locus_tag=MPXV-M5312_HM12_Rivers-086 +NC_063383.1 RefSeq CDS 80001 80558 . + 0 ID=cds-YP_010377085.1;Parent=gene-NBT03_gp082;Dbxref=GenBank:YP_010377085.1,GeneID:72551498;Name=OPG103;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp088%3B RNA polymerase%2C 22 kDa subunit (RPO22)%3B similar to VACV-WR L4R and VACV-Cop J4R;gbkey=CDS;gene=OPG103;locus_tag=NBT03_gp082;product=DNA-directed RNA polymerase subunit;protein_id=YP_010377085.1 +NC_063383.1 RefSeq gene 80618 81019 . - . ID=gene-NBT03_gp083;Dbxref=GeneID:72551499;Name=OPG104;gbkey=Gene;gene=OPG104;gene_biotype=protein_coding;locus_tag=NBT03_gp083;old_locus_tag=MPXV-M5312_HM12_Rivers-087 +NC_063383.1 RefSeq CDS 80618 81019 . - 0 ID=cds-YP_010377086.1;Parent=gene-NBT03_gp083;Dbxref=GenBank:YP_010377086.1,GeneID:72551499;Name=OPG104;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp089%3B essential for virus multiplication%3B IMV membrane protein%3B similar to VACV-WR L5L and VACV-Cop J5L;gbkey=CDS;gene=OPG104;locus_tag=NBT03_gp083;product=Myristylated protein;protein_id=YP_010377086.1 +NC_063383.1 RefSeq gene 81126 84986 . + . ID=gene-NBT03_gp084;Dbxref=GeneID:72551500;Name=OPG105;gbkey=Gene;gene=OPG105;gene_biotype=protein_coding;locus_tag=NBT03_gp084;old_locus_tag=MPXV-M5312_HM12_Rivers-088 +NC_063383.1 RefSeq CDS 81126 84986 . + 0 ID=cds-YP_010377087.1;Parent=gene-NBT03_gp084;Dbxref=GenBank:YP_010377087.1,GeneID:72551500;Name=OPG105;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp090%3B RNA polymerase%2C 147 kDa subunit (RPO147)%3B similar to VACV-WR L6R and VACV-Cop J6R;gbkey=CDS;gene=OPG105;locus_tag=NBT03_gp084;product=DNA-dependent RNA polymerase subunit rpo147;protein_id=YP_010377087.1 +NC_063383.1 RefSeq gene 84983 85498 . - . ID=gene-NBT03_gp085;Dbxref=GeneID:72551501;Name=OPG106;gbkey=Gene;gene=OPG106;gene_biotype=protein_coding;locus_tag=NBT03_gp085;old_locus_tag=MPXV-M5312_HM12_Rivers-089 +NC_063383.1 RefSeq CDS 84983 85498 . - 0 ID=cds-YP_010377088.1;Parent=gene-NBT03_gp085;Dbxref=GenBank:YP_010377088.1,GeneID:72551501;Name=OPG106;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp091%3B tyrosine%3B Tyr/Ser phosphatase%2C IFN-gamma inhibitor%3B similar to VACV-WR H1L and VACV-Cop H1L;gbkey=CDS;gene=OPG106;locus_tag=NBT03_gp085;product=Tyr/ser protein phosphatase;protein_id=YP_010377088.1 +NC_063383.1 RefSeq gene 85512 86081 . + . ID=gene-NBT03_gp086;Dbxref=GeneID:72551502;Name=OPG107;gbkey=Gene;gene=OPG107;gene_biotype=protein_coding;locus_tag=NBT03_gp086;old_locus_tag=MPXV-M5312_HM12_Rivers-090 +NC_063383.1 RefSeq CDS 85512 86081 . + 0 ID=cds-YP_010377089.1;Parent=gene-NBT03_gp086;Dbxref=GenBank:YP_010377089.1,GeneID:72551502;Name=OPG107;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp092%3B IMV membrane protein%3B similar to VACV-WR H2R and VACV-Cop H2R;gbkey=CDS;gene=OPG107;locus_tag=NBT03_gp086;product=Entry-fusion complex essential component;protein_id=YP_010377089.1 +NC_063383.1 RefSeq gene 86085 87059 . - . ID=gene-NBT03_gp087;Dbxref=GeneID:72551503;Name=OPG108;gbkey=Gene;gene=OPG108;gene_biotype=protein_coding;locus_tag=NBT03_gp087;old_locus_tag=MPXV-M5312_HM12_Rivers-091 +NC_063383.1 RefSeq CDS 86085 87059 . - 0 ID=cds-YP_010377090.1;Parent=gene-NBT03_gp087;Dbxref=GenBank:YP_010377090.1,GeneID:72551503;Name=OPG108;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp093%3B IMV surface membrane protein%3B IMV heparin binding surface protein%3B similar to VACV-WR H3L and VACV-Cop H3L;gbkey=CDS;gene=OPG108;locus_tag=NBT03_gp087;product=IMV heparin binding surface protein;protein_id=YP_010377090.1 +NC_063383.1 RefSeq gene 87060 89447 . - . ID=gene-NBT03_gp088;Dbxref=GeneID:72551504;Name=OPG109;gbkey=Gene;gene=OPG109;gene_biotype=protein_coding;locus_tag=NBT03_gp088;old_locus_tag=MPXV-M5312_HM12_Rivers-092 +NC_063383.1 RefSeq CDS 87060 89447 . - 0 ID=cds-YP_010377091.1;Parent=gene-NBT03_gp088;Dbxref=GenBank:YP_010377091.1,GeneID:72551504;Name=OPG109;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp094%3B virion core RNA polymerase-associated protein%2C RAP94%3B similar to VACV-WR H4L and VACV-Cop H4L;gbkey=CDS;gene=OPG109;locus_tag=NBT03_gp088;product=RNA polymerase-associated transcription-specificity factor RAP94;protein_id=YP_010377091.1 +NC_063383.1 RefSeq gene 89632 90264 . + . ID=gene-NBT03_gp089;Dbxref=GeneID:72551505;Name=OPG110;gbkey=Gene;gene=OPG110;gene_biotype=protein_coding;locus_tag=NBT03_gp089;old_locus_tag=MPXV-M5312_HM12_Rivers-093 +NC_063383.1 RefSeq CDS 89632 90264 . + 0 ID=cds-YP_010377092.1;Parent=gene-NBT03_gp089;Dbxref=GenBank:YP_010377092.1,GeneID:72551505;Name=OPG110;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp095%3B virosome-associated late gene transcription factor%2C VLTF-4%3B Ca2+-binding motif%3B similar to VACV-WR H5R and VACV-Cop H5R;gbkey=CDS;gene=OPG110;locus_tag=NBT03_gp089;product=Late transcription factor VLTF-4 (1);protein_id=YP_010377092.1 +NC_063383.1 RefSeq gene 90265 91209 . + . ID=gene-NBT03_gp090;Dbxref=GeneID:72551506;Name=OPG111;gbkey=Gene;gene=OPG111;gene_biotype=protein_coding;locus_tag=NBT03_gp090;old_locus_tag=MPXV-M5312_HM12_Rivers-094 +NC_063383.1 RefSeq CDS 90265 91209 . + 0 ID=cds-YP_010377093.1;Parent=gene-NBT03_gp090;Dbxref=GenBank:YP_010377093.1,GeneID:72551506;Name=OPG111;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp096%3B DNA topoisomerase type I%3B similar to VACV-WR H6R and VACV-Cop H6R;gbkey=CDS;gene=OPG111;locus_tag=NBT03_gp090;product=DNA topoisomerase type I;protein_id=YP_010377093.1 +NC_063383.1 RefSeq gene 91247 91687 . + . ID=gene-NBT03_gp091;Dbxref=GeneID:72551507;Name=OPG112;gbkey=Gene;gene=OPG112;gene_biotype=protein_coding;locus_tag=NBT03_gp091;old_locus_tag=MPXV-M5312_HM12_Rivers-095 +NC_063383.1 RefSeq CDS 91247 91687 . + 0 ID=cds-YP_010377094.1;Parent=gene-NBT03_gp091;Dbxref=GenBank:YP_010377094.1,GeneID:72551507;Name=OPG112;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp097%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR H7R and VACV-Cop H7R;gbkey=CDS;gene=OPG112;locus_tag=NBT03_gp091;product=Late protein H7;protein_id=YP_010377094.1 +NC_063383.1 RefSeq gene 91731 94268 . + . ID=gene-NBT03_gp092;Dbxref=GeneID:72551508;Name=OPG113;gbkey=Gene;gene=OPG113;gene_biotype=protein_coding;locus_tag=NBT03_gp092;old_locus_tag=MPXV-M5312_HM12_Rivers-096 +NC_063383.1 RefSeq CDS 91731 94268 . + 0 ID=cds-YP_010377095.1;Parent=gene-NBT03_gp092;Dbxref=GenBank:YP_010377095.1,GeneID:72551508;Name=OPG113;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp098%3B mRNA capping enzyme%2C large subunit%3B RNA 5' triphosphatase and RNA guanylyl transferase activities%3B similar to VACV-WR E1R and VACV-Cop D1R;gbkey=CDS;gene=OPG113;locus_tag=NBT03_gp092;product=mRNA capping enzyme large subunit;protein_id=YP_010377095.1 +NC_063383.1 RefSeq gene 94227 94667 . - . ID=gene-NBT03_gp093;Dbxref=GeneID:72551509;Name=OPG114;gbkey=Gene;gene=OPG114;gene_biotype=protein_coding;locus_tag=NBT03_gp093;old_locus_tag=MPXV-M5312_HM12_Rivers-097 +NC_063383.1 RefSeq CDS 94227 94667 . - 0 ID=cds-YP_010377096.1;Parent=gene-NBT03_gp093;Dbxref=GenBank:YP_010377096.1,GeneID:72551509;Name=OPG114;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp099%3B virion core protein%3B similar to VACV-WR E2L and VACV-Cop D2L;gbkey=CDS;gene=OPG114;locus_tag=NBT03_gp093;product=Virion protein D2;protein_id=YP_010377096.1 +NC_063383.1 RefSeq gene 94660 95361 . + . ID=gene-NBT03_gp094;Dbxref=GeneID:72551510;Name=OPG115;gbkey=Gene;gene=OPG115;gene_biotype=protein_coding;locus_tag=NBT03_gp094;old_locus_tag=MPXV-M5312_HM12_Rivers-098 +NC_063383.1 RefSeq CDS 94660 95361 . + 0 ID=cds-YP_010377097.1;Parent=gene-NBT03_gp094;Dbxref=GenBank:YP_010377097.1,GeneID:72551510;Name=OPG115;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp100%3B virion core protein%3B similar to VACV-WR E3R and VACV-Cop D3R;gbkey=CDS;gene=OPG115;locus_tag=NBT03_gp094;product=Virion core protein D3;protein_id=YP_010377097.1 +NC_063383.1 RefSeq gene 95361 96017 . + . ID=gene-NBT03_gp095;Dbxref=GeneID:72551511;Name=OPG116;gbkey=Gene;gene=OPG116;gene_biotype=protein_coding;locus_tag=NBT03_gp095;old_locus_tag=MPXV-M5312_HM12_Rivers-099 +NC_063383.1 RefSeq CDS 95361 96017 . + 0 ID=cds-YP_010377098.1;Parent=gene-NBT03_gp095;Dbxref=GenBank:YP_010377098.1,GeneID:72551511;Name=OPG116;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp101%3B uracil DNA glycosylase%3B DNA polymerase processivity factor%3B similar to VACV-WR E4R and VACV-Cop D4R;gbkey=CDS;gene=OPG116;locus_tag=NBT03_gp095;product=Uracil DNA glycosylase superfamily;protein_id=YP_010377098.1 +NC_063383.1 RefSeq gene 96049 98406 . + . ID=gene-NBT03_gp096;Dbxref=GeneID:72551512;Name=OPG117;gbkey=Gene;gene=OPG117;gene_biotype=protein_coding;locus_tag=NBT03_gp096;old_locus_tag=MPXV-M5312_HM12_Rivers-100 +NC_063383.1 RefSeq CDS 96049 98406 . + 0 ID=cds-YP_010377099.1;Parent=gene-NBT03_gp096;Dbxref=GenBank:YP_010377099.1,GeneID:72551512;Name=OPG117;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp102%3B nucleic acid-independent nucleoside triphosphatase%3B NTPase%2C DNA primase%3B similar to VACV-WR E5R and VACV-Cop D5R;gbkey=CDS;gene=OPG117;locus_tag=NBT03_gp096;product=NTPase (1);protein_id=YP_010377099.1 +NC_063383.1 RefSeq gene 98446 100359 . + . ID=gene-NBT03_gp097;Dbxref=GeneID:72551513;Name=OPG118;gbkey=Gene;gene=OPG118;gene_biotype=protein_coding;locus_tag=NBT03_gp097;old_locus_tag=MPXV-M5312_HM12_Rivers-101 +NC_063383.1 RefSeq CDS 98446 100359 . + 0 ID=cds-YP_010377100.1;Parent=gene-NBT03_gp097;Dbxref=GenBank:YP_010377100.1,GeneID:72551513;Name=OPG118;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp103%3B early transcription factor%2C small subunit%2C VETF-s%3B Morphogenesis%3B similar to VACV-WR E6R and VACV-Cop D6R;gbkey=CDS;gene=OPG118;locus_tag=NBT03_gp097;product=Early transcription factor 70 kDa subunit;protein_id=YP_010377100.1 +NC_063383.1 RefSeq gene 100386 100871 . + . ID=gene-NBT03_gp098;Dbxref=GeneID:72551514;Name=OPG119;gbkey=Gene;gene=OPG119;gene_biotype=protein_coding;locus_tag=NBT03_gp098;old_locus_tag=MPXV-M5312_HM12_Rivers-102 +NC_063383.1 RefSeq CDS 100386 100871 . + 0 ID=cds-YP_010377101.1;Parent=gene-NBT03_gp098;Dbxref=GenBank:YP_010377101.1,GeneID:72551514;Name=OPG119;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp104%3B RNA polymerase%2C 18 kDa subunit (RPO18)%3B similar to VACV-WR E7R and VACV-Cop D7R;gbkey=CDS;gene=OPG119;locus_tag=NBT03_gp098;product=RNA polymerase subunit RPO18;protein_id=YP_010377101.1 +NC_063383.1 RefSeq gene 100834 101748 . - . ID=gene-NBT03_gp099;Dbxref=GeneID:72551515;Name=OPG120;gbkey=Gene;gene=OPG120;gene_biotype=protein_coding;locus_tag=NBT03_gp099;old_locus_tag=MPXV-M5312_HM12_Rivers-103 +NC_063383.1 RefSeq CDS 100834 101748 . - 0 ID=cds-YP_010377102.1;Parent=gene-NBT03_gp099;Dbxref=GenBank:YP_010377102.1,GeneID:72551515;Name=OPG120;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp105%3B IMV surface membrane 32 kDa protein%3B binding to cell surface chondroitin sulfate%3B IMV adsorption to cell surface%3B GAG-binding IMV membrane protein%3B similar to VACV-WR E8L and VACV-Cop D8L;gbkey=CDS;gene=OPG120;locus_tag=NBT03_gp099;product=Carbonic anhydrase;protein_id=YP_010377102.1 +NC_063383.1 RefSeq gene 101790 102431 . + . ID=gene-NBT03_gp100;Dbxref=GeneID:72551516;Name=OPG121;gbkey=Gene;gene=OPG121;gene_biotype=protein_coding;locus_tag=NBT03_gp100;old_locus_tag=MPXV-M5312_HM12_Rivers-104 +NC_063383.1 RefSeq CDS 101790 102431 . + 0 ID=cds-YP_010377103.1;Parent=gene-NBT03_gp100;Dbxref=GenBank:YP_010377103.1,GeneID:72551516;Name=OPG121;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp106%3B Mut-like%3B mRNA decapping enzyme%3B similar to VACV-WR E9R and VACV-Cop D9R;gbkey=CDS;gene=OPG121;locus_tag=NBT03_gp100;product=NUDIX domain protein;protein_id=YP_010377103.1 +NC_063383.1 RefSeq gene 102428 103174 . + . ID=gene-NBT03_gp101;Dbxref=GeneID:72551517;Name=OPG122;gbkey=Gene;gene=OPG122;gene_biotype=protein_coding;locus_tag=NBT03_gp101;old_locus_tag=MPXV-M5312_HM12_Rivers-105 +NC_063383.1 RefSeq CDS 102428 103174 . + 0 ID=cds-YP_010377104.1;Parent=gene-NBT03_gp101;Dbxref=GenBank:YP_010377104.1,GeneID:72551517;Name=OPG122;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp107%3B down regulation of gene expression%3B Mut-like%3B mRNA decapping enzyme%3B similar to VACV-WR E10R and VACV-Cop D10R;gbkey=CDS;gene=OPG122;locus_tag=NBT03_gp101;product=MutT motif protein;protein_id=YP_010377104.1 +NC_063383.1 RefSeq gene 103175 105070 . - . ID=gene-NBT03_gp102;Dbxref=GeneID:72551518;Name=OPG123;gbkey=Gene;gene=OPG123;gene_biotype=protein_coding;locus_tag=NBT03_gp102;old_locus_tag=MPXV-M5312_HM12_Rivers-106 +NC_063383.1 RefSeq CDS 103175 105070 . - 0 ID=cds-YP_010377105.1;Parent=gene-NBT03_gp102;Dbxref=GenBank:YP_010377105.1,GeneID:72551518;Name=OPG123;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp108%3B nucleoside triphosphate phosphohydrolase I%2C NPH I%3B DNA-dependent ATPase%3B early gene transcription termination factor%3B similar to VACV-WR E11L and VACV-Cop D11L;gbkey=CDS;gene=OPG123;locus_tag=NBT03_gp102;product=Nucleoside triphosphatase I;protein_id=YP_010377105.1 +NC_063383.1 RefSeq gene 105105 105968 . - . ID=gene-NBT03_gp103;Dbxref=GeneID:72551519;Name=OPG124;gbkey=Gene;gene=OPG124;gene_biotype=protein_coding;locus_tag=NBT03_gp103;old_locus_tag=MPXV-M5312_HM12_Rivers-107 +NC_063383.1 RefSeq CDS 105105 105968 . - 0 ID=cds-YP_010377106.1;Parent=gene-NBT03_gp103;Dbxref=GenBank:YP_010377106.1,GeneID:72551519;Name=OPG124;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp109%3B mRNA capping enzyme small subunit%3B mRNA (guanine-N7-)-methyl-transferase%3B transcription initiation factor%3B similar to VACV-WR E12L and VACV-Cop D12L;gbkey=CDS;gene=OPG124;locus_tag=NBT03_gp103;product=mRNA capping enzyme small subunit;protein_id=YP_010377106.1 +NC_063383.1 RefSeq gene 105999 107654 . - . ID=gene-NBT03_gp104;Dbxref=GeneID:72551520;Name=OPG125;gbkey=Gene;gene=OPG125;gene_biotype=protein_coding;locus_tag=NBT03_gp104;old_locus_tag=MPXV-M5312_HM12_Rivers-108 +NC_063383.1 RefSeq CDS 105999 107654 . - 0 ID=cds-YP_010377107.1;Parent=gene-NBT03_gp104;Dbxref=GenBank:YP_010377107.1,GeneID:72551520;Name=OPG125;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp110%3B protein needed for the formation of immature IMV surface membrane%3B Trimeric virion coat protein (rifampicin res)%3B similar to VACV-WR E13L and VACV-Cop D13L;gbkey=CDS;gene=OPG125;locus_tag=NBT03_gp104;product=Rifampicin resistance protein;protein_id=YP_010377107.1 +NC_063383.1 RefSeq gene 107678 108130 . - . ID=gene-NBT03_gp105;Dbxref=GeneID:72551521;Name=OPG126;gbkey=Gene;gene=OPG126;gene_biotype=protein_coding;locus_tag=NBT03_gp105;old_locus_tag=MPXV-M5312_HM12_Rivers-109 +NC_063383.1 RefSeq CDS 107678 108130 . - 0 ID=cds-YP_010377108.1;Parent=gene-NBT03_gp105;Dbxref=GenBank:YP_010377108.1,GeneID:72551521;Name=OPG126;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp111%3B late gene transcription factor%2C VLTF-2%3B similar to VACV-WR A1L and VACV-Cop A1L;gbkey=CDS;gene=OPG126;locus_tag=NBT03_gp105;product=Late transcription factor VLTF-2 (2);protein_id=YP_010377108.1 +NC_063383.1 RefSeq gene 108151 108825 . - . ID=gene-NBT03_gp106;Dbxref=GeneID:72551522;Name=OPG127;gbkey=Gene;gene=OPG127;gene_biotype=protein_coding;locus_tag=NBT03_gp106;old_locus_tag=MPXV-M5312_HM12_Rivers-110 +NC_063383.1 RefSeq CDS 108151 108825 . - 0 ID=cds-YP_010377109.1;Parent=gene-NBT03_gp106;Dbxref=GenBank:YP_010377109.1,GeneID:72551522;Name=OPG127;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp112%3B late gene transcription factor%2C VLTF-3%3B zinc binding%3B similar to VACV-WR A2L and VACV-Cop A2L;gbkey=CDS;gene=OPG127;locus_tag=NBT03_gp106;product=Late transcription factor VLTF-3 (1);protein_id=YP_010377109.1 +NC_063383.1 RefSeq gene 108822 109055 . - . ID=gene-NBT03_gp107;Dbxref=GeneID:72551523;Name=OPG128;gbkey=Gene;gene=OPG128;gene_biotype=protein_coding;locus_tag=NBT03_gp107;old_locus_tag=MPXV-M5312_HM12_Rivers-111 +NC_063383.1 RefSeq CDS 108822 109055 . - 0 ID=cds-YP_010377110.1;Parent=gene-NBT03_gp107;Dbxref=GenBank:YP_010377110.1,GeneID:72551523;Name=OPG128;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp113%3B S-S bond formation pathway protein%3B similar to VACV-WR A3L and VACV-Cop A2.5L;gbkey=CDS;gene=OPG128;locus_tag=NBT03_gp107;product=S-S bond formation pathway protein;protein_id=YP_010377110.1 +NC_063383.1 RefSeq gene 109070 111004 . - . ID=gene-NBT03_gp108;Dbxref=GeneID:72551524;Name=OPG129;gbkey=Gene;gene=OPG129;gene_biotype=protein_coding;locus_tag=NBT03_gp108;old_locus_tag=MPXV-M5312_HM12_Rivers-112 +NC_063383.1 RefSeq CDS 109070 111004 . - 0 ID=cds-YP_010377111.1;Parent=gene-NBT03_gp108;Dbxref=GenBank:YP_010377111.1,GeneID:72551524;Name=OPG129;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp114%3B major virion core protein p4b%3B P4b precursor%3B similar to VACV-WR A4L and VACV-Cop A3L;gbkey=CDS;gene=OPG129;locus_tag=NBT03_gp108;product=Virion core protein P4b;protein_id=YP_010377111.1 +NC_063383.1 RefSeq gene 111057 111902 . - . ID=gene-NBT03_gp109;Dbxref=GeneID:72551525;Name=OPG130;gbkey=Gene;gene=OPG130;gene_biotype=protein_coding;locus_tag=NBT03_gp109;old_locus_tag=MPXV-M5312_HM12_Rivers-113 +NC_063383.1 RefSeq CDS 111057 111902 . - 0 ID=cds-YP_010377112.1;Parent=gene-NBT03_gp109;Dbxref=GenBank:YP_010377112.1,GeneID:72551525;Name=OPG130;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp115%3B 39 kDa immunodominant virion core protein needed for the progression of IV to infectious IMV%3B 39kDa virion core protein%3B similar to VACV-WR A5L and VACV-Cop A4L;gbkey=CDS;gene=OPG130;locus_tag=NBT03_gp109;product=A5L protein-like;protein_id=YP_010377112.1 +NC_063383.1 RefSeq gene 111940 112425 . + . ID=gene-NBT03_gp110;Dbxref=GeneID:72551526;Name=OPG131;gbkey=Gene;gene=OPG131;gene_biotype=protein_coding;locus_tag=NBT03_gp110;old_locus_tag=MPXV-M5312_HM12_Rivers-114 +NC_063383.1 RefSeq CDS 111940 112425 . + 0 ID=cds-YP_010377113.1;Parent=gene-NBT03_gp110;Dbxref=GenBank:YP_010377113.1,GeneID:72551526;Name=OPG131;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp116%3B precursor of RNA polymerase 22 kDa and 21 kDa%3B RNA polymerase subunit (RPO19)%3B similar to VACV-WR A6R and VACV-Cop A5R;gbkey=CDS;gene=OPG131;locus_tag=NBT03_gp110;product=DNA-directed RNA polymerase 19 kDa subunit;protein_id=YP_010377113.1 +NC_063383.1 RefSeq gene 112422 113540 . - . ID=gene-NBT03_gp111;Dbxref=GeneID:72551527;Name=OPG132;gbkey=Gene;gene=OPG132;gene_biotype=protein_coding;locus_tag=NBT03_gp111;old_locus_tag=MPXV-M5312_HM12_Rivers-115 +NC_063383.1 RefSeq CDS 112422 113540 . - 0 ID=cds-YP_010377114.1;Parent=gene-NBT03_gp111;Dbxref=GenBank:YP_010377114.1,GeneID:72551527;Name=OPG132;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp117%3B Viral membrane assembly proteins (VMAP)%2C core protein%3B similar to VACV-WR A7L and VACV-Cop A6L;gbkey=CDS;gene=OPG132;locus_tag=NBT03_gp111;product=Virion morphogenesis protein;protein_id=YP_010377114.1 +NC_063383.1 RefSeq gene 113564 115696 . - . ID=gene-NBT03_gp112;Dbxref=GeneID:72551528;Name=OPG133;gbkey=Gene;gene=OPG133;gene_biotype=protein_coding;locus_tag=NBT03_gp112;old_locus_tag=MPXV-M5312_HM12_Rivers-116 +NC_063383.1 RefSeq CDS 113564 115696 . - 0 ID=cds-YP_010377115.1;Parent=gene-NBT03_gp112;Dbxref=GenBank:YP_010377115.1,GeneID:72551528;Name=OPG133;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp118%3B early transcription factor%2C large subunit%2C VETF-L%3B needed for morphogenesis of the virion core%3B similar to VACV-WR A8L and VACV-Cop A7L;gbkey=CDS;gene=OPG133;locus_tag=NBT03_gp112;product=Early transcription factor 82 kDa subunit;protein_id=YP_010377115.1 +NC_063383.1 RefSeq gene 115750 116628 . + . ID=gene-NBT03_gp113;Dbxref=GeneID:72551529;Name=OPG134;gbkey=Gene;gene=OPG134;gene_biotype=protein_coding;locus_tag=NBT03_gp113;old_locus_tag=MPXV-M5312_HM12_Rivers-117 +NC_063383.1 RefSeq CDS 115750 116628 . + 0 ID=cds-YP_010377116.1;Parent=gene-NBT03_gp113;Dbxref=GenBank:YP_010377116.1,GeneID:72551529;Name=OPG134;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp119%3B intermediate transcription factor%2C VITF-3 34kda subunit%2C 34 kDa%3B similar to VACV-WR A9R and VACV-Cop A8R;gbkey=CDS;gene=OPG134;locus_tag=NBT03_gp113;product=Intermediate transcription factor VITF-3 (1);protein_id=YP_010377116.1 +NC_063383.1 RefSeq gene 116609 116911 . - . ID=gene-NBT03_gp114;Dbxref=GeneID:72551530;Name=OPG135;gbkey=Gene;gene=OPG135;gene_biotype=protein_coding;locus_tag=NBT03_gp114;old_locus_tag=MPXV-M5312_HM12_Rivers-118 +NC_063383.1 RefSeq CDS 116609 116911 . - 0 ID=cds-YP_010377117.1;Parent=gene-NBT03_gp114;Dbxref=GenBank:YP_010377117.1,GeneID:72551530;Name=OPG135;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp120%3B Viral membrane associated%2C early morphogenesis protein%3B similar to VACV-WR A10L and VACV-Cop A9L;gbkey=CDS;gene=OPG135;locus_tag=NBT03_gp114;product=IMV membrane protein A9;protein_id=YP_010377117.1 +NC_063383.1 RefSeq gene 116912 119587 . - . ID=gene-NBT03_gp115;Dbxref=GeneID:72551531;Name=OPG136;gbkey=Gene;gene=OPG136;gene_biotype=protein_coding;locus_tag=NBT03_gp115;old_locus_tag=MPXV-M5312_HM12_Rivers-119 +NC_063383.1 RefSeq CDS 116912 119587 . - 0 ID=cds-YP_010377118.1;Parent=gene-NBT03_gp115;Dbxref=GenBank:YP_010377118.1,GeneID:72551531;Name=OPG136;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp121%3B major virion core protein p4a%3B P4a precursor%3B similar to VACV-WR A11L and VACV-Cop A10L;gbkey=CDS;gene=OPG136;locus_tag=NBT03_gp115;product=Virion core protein P4a;protein_id=YP_010377118.1 +NC_063383.1 RefSeq gene 119602 120558 . + . ID=gene-NBT03_gp116;Dbxref=GeneID:72551532;Name=OPG137;gbkey=Gene;gene=OPG137;gene_biotype=protein_coding;locus_tag=NBT03_gp116;old_locus_tag=MPXV-M5312_HM12_Rivers-120 +NC_063383.1 RefSeq CDS 119602 120558 . + 0 ID=cds-YP_010377119.1;Parent=gene-NBT03_gp116;Dbxref=GenBank:YP_010377119.1,GeneID:72551532;Name=OPG137;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp122%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR A12R and VACV-Cop A11R;gbkey=CDS;gene=OPG137;locus_tag=NBT03_gp116;product=Viral membrane formation protein;protein_id=YP_010377119.1 +NC_063383.1 RefSeq gene 120560 121132 . - . ID=gene-NBT03_gp117;Dbxref=GeneID:72551533;Name=OPG138;gbkey=Gene;gene=OPG138;gene_biotype=protein_coding;locus_tag=NBT03_gp117;old_locus_tag=MPXV-M5312_HM12_Rivers-121 +NC_063383.1 RefSeq CDS 120560 121132 . - 0 ID=cds-YP_010377120.1;Parent=gene-NBT03_gp117;Dbxref=GenBank:YP_010377120.1,GeneID:72551533;Name=OPG138;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp123%3B Virion core and cleavage processing protein%3B similar to VACV-WR A13L and VACV-Cop A12L;gbkey=CDS;gene=OPG138;locus_tag=NBT03_gp117;product=A12 protein;protein_id=YP_010377120.1 +NC_063383.1 RefSeq gene 121156 121368 . - . ID=gene-NBT03_gp118;Dbxref=GeneID:72551534;Name=OPG139;gbkey=Gene;gene=OPG139;gene_biotype=protein_coding;locus_tag=NBT03_gp118;old_locus_tag=MPXV-M5312_HM12_Rivers-122 +NC_063383.1 RefSeq CDS 121156 121368 . - 0 ID=cds-YP_010377121.1;Parent=gene-NBT03_gp118;Dbxref=GenBank:YP_010377121.1,GeneID:72551534;Name=OPG139;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp124%3B IMV inner and outer membrane protein%3B virion maturation%3B similar to VACV-WR A14L and VACV-Cop A13L;gbkey=CDS;gene=OPG139;locus_tag=NBT03_gp118;product=IMV membrane protein A13L;protein_id=YP_010377121.1 +NC_063383.1 RefSeq gene 121474 121746 . - . ID=gene-NBT03_gp119;Dbxref=GeneID:72551535;Name=OPG140;gbkey=Gene;gene=OPG140;gene_biotype=protein_coding;locus_tag=NBT03_gp119;old_locus_tag=MPXV-M5312_HM12_Rivers-123 +NC_063383.1 RefSeq CDS 121474 121746 . - 0 ID=cds-YP_010377122.1;Parent=gene-NBT03_gp119;Dbxref=GenBank:YP_010377122.1,GeneID:72551535;Name=OPG140;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp125%3B IMV inner membrane protein%3B Essential IMV membrane protein%3B similar to VACV-WR A15L and VACV-Cop A14L;gbkey=CDS;gene=OPG140;locus_tag=NBT03_gp119;product=IMV membrane protein A14;protein_id=YP_010377122.1 +NC_063383.1 RefSeq gene 121763 121924 . - . ID=gene-NBT03_gp120;Dbxref=GeneID:72551536;Name=OPG141;gbkey=Gene;gene=OPG141;gene_biotype=protein_coding;locus_tag=NBT03_gp120;old_locus_tag=MPXV-M5312_HM12_Rivers-124 +NC_063383.1 RefSeq CDS 121763 121924 . - 0 ID=cds-YP_010377123.1;Parent=gene-NBT03_gp120;Dbxref=GenBank:YP_010377123.1,GeneID:72551536;Name=OPG141;Note=Taxonomic breadth: chordopoxvirinae%3B Non-essential IMV membrane protein%3B similar to VACV-WR A15.5L and VACV-Cop A14.5L;gbkey=CDS;gene=OPG141;locus_tag=NBT03_gp120;product=DUF1029 domain protein;protein_id=YP_010377123.1 +NC_063383.1 RefSeq gene 121914 122198 . - . ID=gene-NBT03_gp121;Dbxref=GeneID:72551537;Name=OPG142;gbkey=Gene;gene=OPG142;gene_biotype=protein_coding;locus_tag=NBT03_gp121;old_locus_tag=MPXV-M5312_HM12_Rivers-125 +NC_063383.1 RefSeq CDS 121914 122198 . - 0 ID=cds-YP_010377124.1;Parent=gene-NBT03_gp121;Dbxref=GenBank:YP_010377124.1,GeneID:72551537;Name=OPG142;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp126%3B Core protein%3B similar to VACV-WR A16L and VACV-Cop A15L;gbkey=CDS;gene=OPG142;locus_tag=NBT03_gp121;product=Core protein A15;protein_id=YP_010377124.1 +NC_063383.1 RefSeq gene 122182 123315 . - . ID=gene-NBT03_gp122;Dbxref=GeneID:72551538;Name=OPG143;gbkey=Gene;gene=OPG143;gene_biotype=protein_coding;locus_tag=NBT03_gp122;old_locus_tag=MPXV-M5312_HM12_Rivers-126 +NC_063383.1 RefSeq CDS 122182 123315 . - 0 ID=cds-YP_010377125.1;Parent=gene-NBT03_gp122;Dbxref=GenBank:YP_010377125.1,GeneID:72551538;Name=OPG143;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp127%3B soluble myristylated protein%3B essential for entry/fusion%3B similar to VACV-WR A17L and VACV-Cop A16L;gbkey=CDS;gene=OPG143;locus_tag=NBT03_gp122;product=Myristylated protein;protein_id=YP_010377125.1 +NC_063383.1 RefSeq gene 123318 123932 . - . ID=gene-NBT03_gp123;Dbxref=GeneID:72551539;Name=OPG144;gbkey=Gene;gene=OPG144;gene_biotype=protein_coding;locus_tag=NBT03_gp123;old_locus_tag=MPXV-M5312_HM12_Rivers-127 +NC_063383.1 RefSeq CDS 123318 123932 . - 0 ID=cds-YP_010377126.1;Parent=gene-NBT03_gp123;Dbxref=GenBank:YP_010377126.1,GeneID:72551539;Name=OPG144;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp128%3B IMV surface membrane protein%3B early function in virion morphgenesis%3B similar to VACV-WR A18L and VACV-Cop A17L;gbkey=CDS;gene=OPG144;locus_tag=NBT03_gp123;product=IMV membrane protein P21;protein_id=YP_010377126.1 +NC_063383.1 RefSeq gene 123947 125425 . + . ID=gene-NBT03_gp124;Dbxref=GeneID:72551540;Name=OPG145;gbkey=Gene;gene=OPG145;gene_biotype=protein_coding;locus_tag=NBT03_gp124;old_locus_tag=MPXV-M5312_HM12_Rivers-128 +NC_063383.1 RefSeq CDS 123947 125425 . + 0 ID=cds-YP_010377127.1;Parent=gene-NBT03_gp124;Dbxref=GenBank:YP_010377127.1,GeneID:72551540;Name=OPG145;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp129%3B virion core associated DNA helicase%3B post-replicative negative transcription elongation factor%3B transcript release factor%3B similar to VACV-WR A19R and VACV-Cop A18R;gbkey=CDS;gene=OPG145;locus_tag=NBT03_gp124;product=DNA helicase;protein_id=YP_010377127.1 +NC_063383.1 RefSeq gene 125406 125639 . - . ID=gene-NBT03_gp125;Dbxref=GeneID:72551541;Name=OPG146;gbkey=Gene;gene=OPG146;gene_biotype=protein_coding;locus_tag=NBT03_gp125;old_locus_tag=MPXV-M5312_HM12_Rivers-129 +NC_063383.1 RefSeq CDS 125406 125639 . - 0 ID=cds-YP_010377128.1;Parent=gene-NBT03_gp125;Dbxref=GenBank:YP_010377128.1,GeneID:72551541;Name=OPG146;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp130%3B Zinc finger-like protein%3B similar to VACV-WR A20L and VACV-Cop A19L;gbkey=CDS;gene=OPG146;locus_tag=NBT03_gp125;product=Zinc finger-like protein (1);protein_id=YP_010377128.1 +NC_063383.1 RefSeq gene 125640 125987 . - . ID=gene-NBT03_gp126;Dbxref=GeneID:72551542;Name=OPG147;gbkey=Gene;gene=OPG147;gene_biotype=protein_coding;locus_tag=NBT03_gp126;old_locus_tag=MPXV-M5312_HM12_Rivers-130 +NC_063383.1 RefSeq CDS 125640 125987 . - 0 ID=cds-YP_010377129.1;Parent=gene-NBT03_gp126;Dbxref=GenBank:YP_010377129.1,GeneID:72551542;Name=OPG147;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp131%3B IMV membrane protein%2C entry/fusion complex component%3B similar to VACV-WR A21L and VACV-Cop A21L;gbkey=CDS;gene=OPG147;locus_tag=NBT03_gp126;product=IMV membrane protein A21;protein_id=YP_010377129.1 +NC_063383.1 RefSeq gene 125986 127266 . + . ID=gene-NBT03_gp127;Dbxref=GeneID:72551543;Name=OPG148;gbkey=Gene;gene=OPG148;gene_biotype=protein_coding;locus_tag=NBT03_gp127;old_locus_tag=MPXV-M5312_HM12_Rivers-131 +NC_063383.1 RefSeq CDS 125986 127266 . + 0 ID=cds-YP_010377130.1;Parent=gene-NBT03_gp127;Dbxref=GenBank:YP_010377130.1,GeneID:72551543;Name=OPG148;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp132%3B processivity factor for the viral DNA polymerase%2C VPF%3B similar to VACV-WR A22R and VACV-Cop A20R;gbkey=CDS;gene=OPG148;locus_tag=NBT03_gp127;product=DNA polymerase processivity factor;protein_id=YP_010377130.1 +NC_063383.1 RefSeq gene 127196 127759 . + . ID=gene-NBT03_gp128;Dbxref=GeneID:72551544;Name=OPG149;gbkey=Gene;gene=OPG149;gene_biotype=protein_coding;locus_tag=NBT03_gp128;old_locus_tag=MPXV-M5312_HM12_Rivers-132 +NC_063383.1 RefSeq CDS 127196 127759 . + 0 ID=cds-YP_010377131.1;Parent=gene-NBT03_gp128;Dbxref=GenBank:YP_010377131.1,GeneID:72551544;Name=OPG149;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp133%3B Holliday junction resolvase%3B similar to VACV-WR A23R and VACV-Cop A22R;gbkey=CDS;gene=OPG149;locus_tag=NBT03_gp128;product=Holliday junction resolvase;protein_id=YP_010377131.1 +NC_063383.1 RefSeq gene 127779 128927 . + . ID=gene-NBT03_gp129;Dbxref=GeneID:72551545;Name=OPG150;gbkey=Gene;gene=OPG150;gene_biotype=protein_coding;locus_tag=NBT03_gp129;old_locus_tag=MPXV-M5312_HM12_Rivers-133 +NC_063383.1 RefSeq CDS 127779 128927 . + 0 ID=cds-YP_010377132.1;Parent=gene-NBT03_gp129;Dbxref=GenBank:YP_010377132.1,GeneID:72551545;Name=OPG150;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp134%3B intermediate transcription factor%2C VITF-3%2C 45 kDa subunit%3B similar to VACV-WR A24R and VACV-Cop A23R;gbkey=CDS;gene=OPG150;locus_tag=NBT03_gp129;product=Intermediate transcription factor VITF-3 (2);protein_id=YP_010377132.1 +NC_063383.1 RefSeq gene 128924 132418 . + . ID=gene-NBT03_gp130;Dbxref=GeneID:72551546;Name=OPG151;gbkey=Gene;gene=OPG151;gene_biotype=protein_coding;locus_tag=NBT03_gp130;old_locus_tag=MPXV-M5312_HM12_Rivers-134 +NC_063383.1 RefSeq CDS 128924 132418 . + 0 ID=cds-YP_010377133.1;Parent=gene-NBT03_gp130;Dbxref=GenBank:YP_010377133.1,GeneID:72551546;Name=OPG151;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp135%3B RNA polymerase%2C 132 kDa subunit (RPO132)%3B similar to VACV-WR A25R and VACV-Cop A24R;gbkey=CDS;gene=OPG151;locus_tag=NBT03_gp130;product=DNA-dependent RNA polymerase subunit rpo132;protein_id=YP_010377133.1 +NC_063383.1 RefSeq sequence_feature 132396 136092 . - . ID=id-NC_063383.1:132396..136092;exon_number=OPG152;gbkey=misc_feature;number=OPG152 +NC_063383.1 RefSeq gene 136138 137667 . - . ID=gene-NBT03_gp131;Dbxref=GeneID:72551547;Name=OPG153;gbkey=Gene;gene=OPG153;gene_biotype=protein_coding;locus_tag=NBT03_gp131;old_locus_tag=MPXV-M5312_HM12_Rivers-137 +NC_063383.1 RefSeq CDS 136138 137667 . - 0 ID=cds-YP_010377134.1;Parent=gene-NBT03_gp131;Dbxref=GenBank:YP_010377134.1,GeneID:72551547;Name=OPG153;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp138%3B major component of IMV surface tubules%3B A-type inclusion protein%3B P4c precursor%3B similar to VACV-WR A28L and VACV-Cop A26L;gbkey=CDS;gene=OPG153;locus_tag=NBT03_gp131;product=Orthopoxvirus A26L/A30L protein;protein_id=YP_010377134.1 +NC_063383.1 RefSeq gene 137718 138050 . - . ID=gene-NBT03_gp132;Dbxref=GeneID:72551548;Name=OPG154;gbkey=Gene;gene=OPG154;gene_biotype=protein_coding;locus_tag=NBT03_gp132;old_locus_tag=MPXV-M5312_HM12_Rivers-138 +NC_063383.1 RefSeq CDS 137718 138050 . - 0 ID=cds-YP_010377135.1;Parent=gene-NBT03_gp132;Dbxref=GenBank:YP_010377135.1,GeneID:72551548;Name=OPG154;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp139%3B IMV surface membrane 14 kDa fusion protein%3B binding to cell surface heparan%3B similar to VACV-WR A29L and VACV-Cop A27L;gbkey=CDS;gene=OPG154;locus_tag=NBT03_gp132;product=IMV surface fusion protein;protein_id=YP_010377135.1 +NC_063383.1 RefSeq gene 138051 138491 . - . ID=gene-NBT03_gp133;Dbxref=GeneID:72551549;Name=OPG155;gbkey=Gene;gene=OPG155;gene_biotype=protein_coding;locus_tag=NBT03_gp133;old_locus_tag=MPXV-M5312_HM12_Rivers-139 +NC_063383.1 RefSeq CDS 138051 138491 . - 0 ID=cds-YP_010377136.1;Parent=gene-NBT03_gp133;Dbxref=GenBank:YP_010377136.1,GeneID:72551549;Name=OPG155;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp140%3B IMV MP/Virus entry%3B similar to VACV-WR A30L and VACV-Cop A28L;gbkey=CDS;gene=OPG155;locus_tag=NBT03_gp133;product=Envelope protein A28 homolog;protein_id=YP_010377136.1 +NC_063383.1 RefSeq gene 138492 139409 . - . ID=gene-NBT03_gp134;Dbxref=GeneID:72551550;Name=OPG156;gbkey=Gene;gene=OPG156;gene_biotype=protein_coding;locus_tag=NBT03_gp134;old_locus_tag=MPXV-M5312_HM12_Rivers-140 +NC_063383.1 RefSeq CDS 138492 139409 . - 0 ID=cds-YP_010377137.1;Parent=gene-NBT03_gp134;Dbxref=GenBank:YP_010377137.1,GeneID:72551550;Name=OPG156;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp141%3B RNA polymerase%2C 35 kDa subunit (RPO35)%3B similar to VACV-WR A31L and VACV-Cop A29L;gbkey=CDS;gene=OPG156;locus_tag=NBT03_gp134;product=DNA-directed RNA polymerase 35 kDa subunit;protein_id=YP_010377137.1 +NC_063383.1 RefSeq gene 139372 139608 . - . ID=gene-NBT03_gp135;Dbxref=GeneID:72551551;Name=OPG157;gbkey=Gene;gene=OPG157;gene_biotype=protein_coding;locus_tag=NBT03_gp135;old_locus_tag=MPXV-M5312_HM12_Rivers-141 +NC_063383.1 RefSeq CDS 139372 139608 . - 0 ID=cds-YP_010377138.1;Parent=gene-NBT03_gp135;Dbxref=GenBank:YP_010377138.1,GeneID:72551551;Name=OPG157;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp142%3B IMV protein%3B similar to VACV-WR A32L and VACV-Cop A30L;gbkey=CDS;gene=OPG157;locus_tag=NBT03_gp135;product=IMV membrane protein A30;protein_id=YP_010377138.1 +NC_063383.1 RefSeq gene 139641 139769 . - . ID=gene-NBT03_gp136;Dbxref=GeneID:72551552;Name=OPG158;gbkey=Gene;gene=OPG158;gene_biotype=protein_coding;locus_tag=NBT03_gp136;old_locus_tag=MPXV-M5312_HM12_Rivers-142 +NC_063383.1 RefSeq CDS 139641 139769 . - 0 ID=cds-YP_010377139.1;Parent=gene-NBT03_gp136;Dbxref=GenBank:YP_010377139.1,GeneID:72551552;Name=OPG158;Note=Viral membrane assembly proteins (VMAP)%3B similar to VACV-Cop A30.5L;gbkey=CDS;gene=OPG158;locus_tag=NBT03_gp136;product=A32.5L;protein_id=YP_010377139.1 +NC_063383.1 RefSeq gene 139768 140205 . + . ID=gene-NBT03_gp137;Dbxref=GeneID:72551553;Name=OPG159;gbkey=Gene;gene=OPG159;gene_biotype=protein_coding;locus_tag=NBT03_gp137;old_locus_tag=MPXV-M5312_HM12_Rivers-143 +NC_063383.1 RefSeq CDS 139768 140205 . + 0 ID=cds-YP_010377140.1;Parent=gene-NBT03_gp137;Dbxref=GenBank:YP_010377140.1,GeneID:72551553;Name=OPG159;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp143%3B Hypothetical protein%3B similar to VACV-WR A33R and VACV-Cop A31R;gbkey=CDS;gene=OPG159;locus_tag=NBT03_gp137;product=CPXV166 protein;protein_id=YP_010377140.1 +NC_063383.1 RefSeq gene 140172 141074 . - . ID=gene-NBT03_gp138;Dbxref=GeneID:72551554;Name=OPG160;gbkey=Gene;gene=OPG160;gene_biotype=protein_coding;locus_tag=NBT03_gp138;old_locus_tag=MPXV-M5312_HM12_Rivers-144 +NC_063383.1 RefSeq CDS 140172 141074 . - 0 ID=cds-YP_010377141.1;Parent=gene-NBT03_gp138;Dbxref=GenBank:YP_010377141.1,GeneID:72551554;Name=OPG160;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp144%3B DNA packaging into virion%3B NTP-binding motif A%3B ATPase/DNA packaging protein%3B similar to VACV-WR A34L and VACV-Cop A32L;gbkey=CDS;gene=OPG160;locus_tag=NBT03_gp138;product=ATPase A32;protein_id=YP_010377141.1 +NC_063383.1 RefSeq gene 141102 141647 . + . ID=gene-NBT03_gp139;Dbxref=GeneID:72551555;Name=OPG161;gbkey=Gene;gene=OPG161;gene_biotype=protein_coding;locus_tag=NBT03_gp139;old_locus_tag=MPXV-M5312_HM12_Rivers-145 +NC_063383.1 RefSeq CDS 141102 141647 . + 0 ID=cds-YP_010377142.1;Parent=gene-NBT03_gp139;Dbxref=GenBank:YP_010377142.1,GeneID:72551555;Name=OPG161;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp145%3B EEV envelope glycoprotein%2C needed for formation of actin-containing microvilli and cell-to-cell spread of virion%3B interacts with VAC A36R%3B EEV membrane phosphoglycoprotein%2C C-type lectin-like domain%3B similar to VACV-WR A35R and VACV-Cop A33R;gbkey=CDS;gene=OPG161;locus_tag=NBT03_gp139;product=EEV glycoprotein (1);protein_id=YP_010377142.1 +NC_063383.1 RefSeq gene 141652 142158 . + . ID=gene-NBT03_gp140;Dbxref=GeneID:72551556;Name=OPG162;gbkey=Gene;gene=OPG162;gene_biotype=protein_coding;locus_tag=NBT03_gp140;old_locus_tag=MPXV-M5312_HM12_Rivers-146 +NC_063383.1 RefSeq CDS 141652 142158 . + 0 ID=cds-YP_010377143.1;Parent=gene-NBT03_gp140;Dbxref=GenBank:YP_010377143.1,GeneID:72551556;Name=OPG162;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp146%3B EEV envelope glycoprotein%2C lectin-like%3B required for infectivity of EEV%2C formation of actin-containing microvilli%2C and cell-to-cell spread of virion%3B C-type lectin-like IEV/EEV glycoprotein%3B similar to VACV-WR A36R and VACV-Cop A34R;gbkey=CDS;gene=OPG162;locus_tag=NBT03_gp140;product=EEV glycoprotein (2);protein_id=YP_010377143.1 +NC_063383.1 RefSeq gene 142202 142732 . + . ID=gene-NBT03_gp141;Dbxref=GeneID:72551557;Name=OPG163;gbkey=Gene;gene=OPG163;gene_biotype=protein_coding;locus_tag=NBT03_gp141;old_locus_tag=MPXV-M5312_HM12_Rivers-147 +NC_063383.1 RefSeq CDS 142202 142732 . + 0 ID=cds-YP_010377144.1;Parent=gene-NBT03_gp141;Dbxref=GenBank:YP_010377144.1,GeneID:72551557;Name=OPG163;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp147%3B MHC class II antigen presentation inhibitor%3B similar to VACV-WR A37R and VACV-Cop A35R;gbkey=CDS;gene=OPG163;locus_tag=NBT03_gp141;product=MHC class II antigen presentation inhibitor;protein_id=YP_010377144.1 +NC_063383.1 RefSeq gene 142778 143464 . + . ID=gene-NBT03_gp142;Dbxref=GeneID:72551558;Name=OPG164;gbkey=Gene;gene=OPG164;gene_biotype=protein_coding;locus_tag=NBT03_gp142;old_locus_tag=MPXV-M5312_HM12_Rivers-148 +NC_063383.1 RefSeq CDS 142778 143464 . + 0 ID=cds-YP_010377145.1;Parent=gene-NBT03_gp142;Dbxref=GenBank:YP_010377145.1,GeneID:72551558;Name=OPG164;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp148%3B IEV but not CEV envelope protein%3B plays critical role for actin tail formation%3B interacts with VAC A33R and A34R%3B IEV transmembrane phosphoprotein%3B similar to VACV-WR A38R and VACV-Cop A36R;gbkey=CDS;gene=OPG164;locus_tag=NBT03_gp142;product=IEV transmembrane phosphoprotein;protein_id=YP_010377145.1 +NC_063383.1 RefSeq gene 143516 144322 . + . ID=gene-NBT03_gp143;Dbxref=GeneID:72551559;Name=OPG165;gbkey=Gene;gene=OPG165;gene_biotype=protein_coding;locus_tag=NBT03_gp143;old_locus_tag=MPXV-M5312_HM12_Rivers-149 +NC_063383.1 RefSeq CDS 143516 144322 . + 0 ID=cds-YP_010377146.1;Parent=gene-NBT03_gp143;Dbxref=GenBank:YP_010377146.1,GeneID:72551559;Name=OPG165;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp149%3B Hypothetical protein%3B similar to VACV-WR A39R and VACV-Cop A37R;gbkey=CDS;gene=OPG165;locus_tag=NBT03_gp143;product=CPXV173 protein;protein_id=YP_010377146.1 +NC_063383.1 RefSeq gene 144398 144577 . + . ID=gene-NBT03_gp144;Dbxref=GeneID:72551560;Name=OPG166;gbkey=Gene;gene=OPG166;gene_biotype=protein_coding;locus_tag=NBT03_gp144 +NC_063383.1 RefSeq CDS 144398 144577 . + 0 ID=cds-YP_010415322.1;Parent=gene-NBT03_gp144;Dbxref=GenBank:YP_010415322.1,GeneID:72551560;Name=OPG166;Note=Hypothetical protein%3B according to YP_233043.1%2C this VACV-WR protein was purified by sucrose gradient centrifugation%3B similar to VACWR161 and VARGAR-A43R;gbkey=CDS;gene=OPG166;locus_tag=NBT03_gp144;product=hypothetical protein;protein_id=YP_010415322.1 +NC_063383.1 RefSeq gene 144574 145407 . - . ID=gene-NBT03_gp145;Dbxref=GeneID:72551561;Name=OPG167;gbkey=Gene;gene=OPG167;gene_biotype=protein_coding;locus_tag=NBT03_gp145;old_locus_tag=MPXV-M5312_HM12_Rivers-150 +NC_063383.1 RefSeq CDS 144574 145407 . - 0 ID=cds-YP_010377147.1;Parent=gene-NBT03_gp145;Dbxref=GenBank:YP_010377147.1,GeneID:72551561;Name=OPG167;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp150%3B integral membrane glycoprotein%3B immunoglobulin-like%3B regulation of the influx of extracellular Ca2+%3B CD47-like%3B similar to VACV-WR A40L and VACV-Cop A38L;gbkey=CDS;gene=OPG167;locus_tag=NBT03_gp145;product=CD47-like protein;protein_id=YP_010377147.1 +NC_063383.1 RefSeq sequence_feature 145423 145856 . + . ID=id-NC_063383.1:145423..145856;exon_number=OPG168;gbkey=misc_feature;number=OPG168 +NC_063383.1 RefSeq sequence_feature 145857 146039 . + . ID=id-NC_063383.1:145857..146039;exon_number=OPG169;gbkey=misc_feature;number=OPG169 +NC_063383.1 RefSeq gene 146113 146778 . - . ID=gene-NBT03_gp146;Dbxref=GeneID:72551562;Name=OPG170;gbkey=Gene;gene=OPG170;gene_biotype=protein_coding;locus_tag=NBT03_gp146;old_locus_tag=MPXV-M5312_HM12_Rivers-151 +NC_063383.1 RefSeq CDS 146113 146778 . - 0 ID=cds-YP_010377148.1;Parent=gene-NBT03_gp146;Dbxref=GenBank:YP_010377148.1,GeneID:72551562;Name=OPG170;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp151%3B secreted protein reducing infiltration of inflammatory cells into the infected area%3B Chemokine binding protein%3B similar to VACV-WR A41L and VACV-Cop A41L;gbkey=CDS;gene=OPG170;locus_tag=NBT03_gp146;product=Chemokine binding protein;protein_id=YP_010377148.1 +NC_063383.1 RefSeq gene 146988 147389 . + . ID=gene-NBT03_gp147;Dbxref=GeneID:72551563;Name=OPG171;gbkey=Gene;gene=OPG171;gene_biotype=protein_coding;locus_tag=NBT03_gp147;old_locus_tag=MPXV-M5312_HM12_Rivers-152 +NC_063383.1 RefSeq CDS 146988 147389 . + 0 ID=cds-YP_010377149.1;Parent=gene-NBT03_gp147;Dbxref=GenBank:YP_010377149.1,GeneID:72551563;Name=OPG171;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp152%3B Profilin-like protein%2C ATI-localized%3B similar to VACV-WR A42R and VACV-Cop A42R;gbkey=CDS;gene=OPG171;locus_tag=NBT03_gp147;product=Profilin domain protein;protein_id=YP_010377149.1 +NC_063383.1 RefSeq gene 147427 148017 . + . ID=gene-NBT03_gp148;Dbxref=GeneID:72551564;Name=OPG172;gbkey=Gene;gene=OPG172;gene_biotype=protein_coding;locus_tag=NBT03_gp148;old_locus_tag=MPXV-M5312_HM12_Rivers-153 +NC_063383.1 RefSeq CDS 147427 148017 . + 0 ID=cds-YP_010377150.1;Parent=gene-NBT03_gp148;Dbxref=GenBank:YP_010377150.1,GeneID:72551564;Name=OPG172;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp153%3B Type I membrane glycoprotein%3B similar to VACV-WR A43R and VACV-Cop A43R;gbkey=CDS;gene=OPG172;locus_tag=NBT03_gp148;product=Type-I membrane glycoprotein;protein_id=YP_010377150.1 +NC_063383.1 RefSeq gene 148037 148261 . + . ID=gene-NBT03_gp149;Dbxref=GeneID:72551565;Name=OPG173;gbkey=Gene;gene=OPG173;gene_biotype=protein_coding;locus_tag=NBT03_gp149;old_locus_tag=MPXV-M5312_HM12_Rivers-154 +NC_063383.1 RefSeq CDS 148037 148261 . + 0 ID=cds-YP_010377151.1;Parent=gene-NBT03_gp149;Dbxref=GenBank:YP_010377151.1,GeneID:72551565;Name=OPG173;Note=Old product: MPXVgp154%3B Hypothetical protein%3B similar to VACV-WR A44R and VACV-Cop A43.5R;gbkey=CDS;gene=OPG173;locus_tag=NBT03_gp149;product=MPXVgp154;protein_id=YP_010377151.1 +NC_063383.1 RefSeq gene 148355 149395 . - . ID=gene-NBT03_gp150;Dbxref=GeneID:72551566;Name=OPG174;gbkey=Gene;gene=OPG174;gene_biotype=protein_coding;locus_tag=NBT03_gp150;old_locus_tag=MPXV-M5312_HM12_Rivers-155 +NC_063383.1 RefSeq CDS 148355 149395 . - 0 ID=cds-YP_010377152.1;Parent=gene-NBT03_gp150;Dbxref=GenBank:YP_010377152.1,GeneID:72551566;Name=OPG174;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp155%3B 3-b-Hydroxy-delta5-steroid dehydrogenase%3B 3 beta-hydroxysteroid dehydrogenase/delta 5->4 isomerase%3B similar to VACV-WR A45L and VACV-Cop A44L;gbkey=CDS;gene=OPG174;locus_tag=NBT03_gp150;product=Hydroxysteroid dehydrogenase;protein_id=YP_010377152.1 +NC_063383.1 RefSeq gene 149442 149819 . + . ID=gene-NBT03_gp151;Dbxref=GeneID:72551567;Name=OPG175;gbkey=Gene;gene=OPG175;gene_biotype=protein_coding;locus_tag=NBT03_gp151;old_locus_tag=MPXV-M5312_HM12_Rivers-156 +NC_063383.1 RefSeq CDS 149442 149819 . + 0 ID=cds-YP_010377153.1;Parent=gene-NBT03_gp151;Dbxref=GenBank:YP_010377153.1,GeneID:72551567;Name=OPG175;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp156%3B virion core protein%3B Inactive Cu-Zn superoxide dismutase-like virion protein%3B similar to VACV-WR A46R and VACV-Cop A45R;gbkey=CDS;gene=OPG175;locus_tag=NBT03_gp151;product=Copper/zinc superoxide dismutase;protein_id=YP_010377153.1 +NC_063383.1 RefSeq gene 149809 150531 . + . ID=gene-NBT03_gp152;Dbxref=GeneID:72551568;Name=OPG176;gbkey=Gene;gene=OPG176;gene_biotype=protein_coding;locus_tag=NBT03_gp152;old_locus_tag=MPXV-M5312_HM12_Rivers-157 +NC_063383.1 RefSeq CDS 149809 150531 . + 0 ID=cds-YP_010377154.1;Parent=gene-NBT03_gp152;Dbxref=GenBank:YP_010377154.1,GeneID:72551568;Name=OPG176;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp157%3B IL-1/TLR signaling inhibitor%3B similar to VACV-WR A47R and VACV-Cop A46R;gbkey=CDS;gene=OPG176;locus_tag=NBT03_gp152;product=Bcl-2-like protein;protein_id=YP_010377154.1 +NC_063383.1 RefSeq sequence_feature 150684 151407 . - . ID=id-NC_063383.1:150684..151407;exon_number=OPG177;gbkey=misc_feature;number=OPG177 +NC_063383.1 RefSeq gene 151509 152123 . + . ID=gene-NBT03_gp153;Dbxref=GeneID:72551569;Name=OPG178;gbkey=Gene;gene=OPG178;gene_biotype=protein_coding;locus_tag=NBT03_gp153;old_locus_tag=MPXV-M5312_HM12_Rivers-158 +NC_063383.1 RefSeq CDS 151509 152123 . + 0 ID=cds-YP_010377155.1;Parent=gene-NBT03_gp153;Dbxref=GenBank:YP_010377155.1,GeneID:72551569;Name=OPG178;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp159%3B thymidylate kinase%3B start of ORF is missing approx. 37 AA compared to CPXVs%3B similar to VACV-WR A49R and VACV-Cop A48R;gbkey=CDS;gene=OPG178;locus_tag=NBT03_gp153;product=Thymidylate kinase;protein_id=YP_010377155.1 +NC_063383.1 RefSeq sequence_feature 152172 152660 . + . ID=id-NC_063383.1:152172..152660;exon_number=OPG179;gbkey=misc_feature;number=OPG179 +NC_063383.1 RefSeq gene 152692 154371 . + . ID=gene-NBT03_gp154;Dbxref=GeneID:72551570;Name=OPG180;gbkey=Gene;gene=OPG180;gene_biotype=protein_coding;locus_tag=NBT03_gp154;old_locus_tag=MPXV-M5312_HM12_Rivers-159 +NC_063383.1 RefSeq CDS 152692 154371 . + 0 ID=cds-YP_010377156.1;Parent=gene-NBT03_gp154;Dbxref=GenBank:YP_010377156.1,GeneID:72551570;Name=OPG180;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp160%3B ATP-dependent DNA ligase%3B similar to VACV-WR A50R and VACV-Cop A50R;gbkey=CDS;gene=OPG180;locus_tag=NBT03_gp154;product=DNA ligase (2);protein_id=YP_010377156.1 +NC_063383.1 RefSeq gene 154412 155416 . + . ID=gene-NBT03_gp155;Dbxref=GeneID:72551571;Name=OPG181;gbkey=Gene;gene=OPG181;gene_biotype=protein_coding;locus_tag=NBT03_gp155;old_locus_tag=MPXV-M5312_HM12_Rivers-160 +NC_063383.1 RefSeq CDS 154412 155416 . + 0 ID=cds-YP_010377157.1;Parent=gene-NBT03_gp155;Dbxref=GenBank:YP_010377157.1,GeneID:72551571;Name=OPG181;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp161%3B Hypothetical protein%3B similar to VACV-WR A51R and VACV-Cop A51R;gbkey=CDS;gene=OPG181;locus_tag=NBT03_gp155;product=M137R;protein_id=YP_010377157.1 +NC_063383.1 RefSeq sequence_feature 155485 156037 . + . ID=id-NC_063383.1:155485..156037;exon_number=OPG182;gbkey=misc_feature;number=OPG182 +NC_063383.1 RefSeq sequence_feature 156355 156916 . + . ID=id-NC_063383.1:156355..156916;exon_number=OPG183;gbkey=misc_feature;number=OPG183 +NC_063383.1 RefSeq sequence_feature 157176 158867 . + . ID=id-NC_063383.1:157176..158867;exon_number=OPG184;gbkey=misc_feature;number=OPG184 +NC_063383.1 RefSeq gene 158917 159858 . + . ID=gene-NBT03_gp156;Dbxref=GeneID:72551572;Name=OPG185;gbkey=Gene;gene=OPG185;gene_biotype=protein_coding;locus_tag=NBT03_gp156;old_locus_tag=MPXV-M5312_HM12_Rivers-162 +NC_063383.1 RefSeq CDS 158917 159858 . + 0 ID=cds-YP_010377158.1;Parent=gene-NBT03_gp156;Dbxref=GenBank:YP_010377158.1,GeneID:72551572;Name=OPG185;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp163%3B EEV envelope and cell membrane glycoprotein hemagglutinin%3B inhibition of the ability of infected cells to fuse%3B interacts with VAC F13L%3B similar to VACV-WR B2R and VACV-Cop A56R;gbkey=CDS;gene=OPG185;locus_tag=NBT03_gp156;product=Hemagglutinin;protein_id=YP_010377158.1 +NC_063383.1 RefSeq sequence_feature 159876 160470 . + . ID=id-NC_063383.1:159876..160470;exon_number=OPG186;gbkey=misc_feature;number=OPG186 +NC_063383.1 RefSeq gene 160622 161533 . + . ID=gene-NBT03_gp157;Dbxref=GeneID:72551573;Name=OPG187;gbkey=Gene;gene=OPG187;gene_biotype=protein_coding;locus_tag=NBT03_gp157;old_locus_tag=MPXV-M5312_HM12_Rivers-163 +NC_063383.1 RefSeq CDS 160622 161533 . + 0 ID=cds-YP_010377159.1;Parent=gene-NBT03_gp157;Dbxref=GenBank:YP_010377159.1,GeneID:72551573;Name=OPG187;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp164%3B serine%3B Ser/Thr Kinase%3B similar to VACV-WR B3R and VACV-Cop B1R;gbkey=CDS;gene=OPG187;locus_tag=NBT03_gp157;product=Ser/thr kinase;protein_id=YP_010377159.1 +NC_063383.1 RefSeq gene 161596 163107 . + . ID=gene-NBT03_gp158;Dbxref=GeneID:72551574;Name=OPG188;gbkey=Gene;gene=OPG188;gene_biotype=protein_coding;locus_tag=NBT03_gp158;old_locus_tag=MPXV-M5312_HM12_Rivers-164 +NC_063383.1 RefSeq CDS 161596 163107 . + 0 ID=cds-YP_010377160.1;Parent=gene-NBT03_gp158;Dbxref=GenBank:YP_010377160.1,GeneID:72551574;Name=OPG188;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp165%3B schlafen-like%3B similar to VACV-WR B4R and VACV-Cop B2R;gbkey=CDS;gene=OPG188;locus_tag=NBT03_gp158;product=Schlafen (1);protein_id=YP_010377160.1 +NC_063383.1 RefSeq gene 163333 165018 . + . ID=gene-NBT03_gp159;Dbxref=GeneID:72551575;Name=OPG189;gbkey=Gene;gene=OPG189;gene_biotype=protein_coding;locus_tag=NBT03_gp159;old_locus_tag=MPXV-M5312_HM12_Rivers-165 +NC_063383.1 RefSeq CDS 163333 165018 . + 0 ID=cds-YP_010377161.1;Parent=gene-NBT03_gp159;Dbxref=GenBank:YP_010377161.1,GeneID:72551575;Name=OPG189;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp166%3B ankyrin-like%3B similar to VACV-WR B5R and VACV-Cop B4R;gbkey=CDS;gene=OPG189;locus_tag=NBT03_gp159;product=Ankyrin repeat protein (25);protein_id=YP_010377161.1 +NC_063383.1 RefSeq gene 165122 166075 . + . ID=gene-NBT03_gp160;Dbxref=GeneID:72551576;Name=OPG190;gbkey=Gene;gene=OPG190;gene_biotype=protein_coding;locus_tag=NBT03_gp160;old_locus_tag=MPXV-M5312_HM12_Rivers-166 +NC_063383.1 RefSeq CDS 165122 166075 . + 0 ID=cds-YP_010377162.1;Parent=gene-NBT03_gp160;Dbxref=GenBank:YP_010377162.1,GeneID:72551576;Name=OPG190;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp167%3B palmitated 42 kDa glycoprotein located both on the membranes of infected cells and on EEV envelope%3B complement control protein-like%3B EEV type-1 membrane glycoprotein%2C protective antigen%3B similar to VACV-WR B6R and VACV-Cop B5R;gbkey=CDS;gene=OPG190;locus_tag=NBT03_gp160;product=EEV type-I membrane glycoprotein;protein_id=YP_010377162.1 +NC_063383.1 RefSeq gene 166161 166667 . + . ID=gene-NBT03_gp161;Dbxref=GeneID:72551577;Name=OPG191;gbkey=Gene;gene=OPG191;gene_biotype=protein_coding;locus_tag=NBT03_gp161;old_locus_tag=MPXV-M5312_HM12_Rivers-167 +NC_063383.1 RefSeq CDS 166161 166667 . + 0 ID=cds-YP_010377163.1;Parent=gene-NBT03_gp161;Dbxref=GenBank:YP_010377163.1,GeneID:72551577;Name=OPG191;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp168%3B Ankyrin-like protein%3B similar to VACV-WR B7R and VACV-Cop B6R;gbkey=CDS;gene=OPG191;locus_tag=NBT03_gp161;product=Ankyrin-like protein (46);protein_id=YP_010377163.1 +NC_063383.1 RefSeq gene 166731 167279 . + . ID=gene-NBT03_gp162;Dbxref=GeneID:72551578;Name=OPG192;gbkey=Gene;gene=OPG192;gene_biotype=protein_coding;locus_tag=NBT03_gp162;old_locus_tag=MPXV-M5312_HM12_Rivers-168 +NC_063383.1 RefSeq CDS 166731 167279 . + 0 ID=cds-YP_010377164.1;Parent=gene-NBT03_gp162;Dbxref=GenBank:YP_010377164.1,GeneID:72551578;Name=OPG192;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp169%3B Virulence%2C ER resident%3B similar to VACV-WR B8R and VACV-Cop B7R;gbkey=CDS;gene=OPG192;locus_tag=NBT03_gp162;product=Virulence protein;protein_id=YP_010377164.1 +NC_063383.1 RefSeq gene 167334 168137 . + . ID=gene-NBT03_gp163;Dbxref=GeneID:72551579;Name=OPG193;gbkey=Gene;gene=OPG193;gene_biotype=protein_coding;locus_tag=NBT03_gp163;old_locus_tag=MPXV-M5312_HM12_Rivers-169 +NC_063383.1 RefSeq CDS 167334 168137 . + 0 ID=cds-YP_010377165.1;Parent=gene-NBT03_gp163;Dbxref=GenBank:YP_010377165.1,GeneID:72551579;Name=OPG193;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp170%3B secreted IFN-g binding protein%3B Soluble IFN-g receptor-like protein%3B similar to VACV-WR B9R and VACV-Cop B8R;gbkey=CDS;gene=OPG193;locus_tag=NBT03_gp163;product=Soluble interferon-gamma receptor-like protein;protein_id=YP_010377165.1 +NC_063383.1 RefSeq gene 168230 168895 . + . ID=gene-NBT03_gp164;Dbxref=GeneID:72551580;Name=OPG195;gbkey=Gene;gene=OPG195;gene_biotype=protein_coding;locus_tag=NBT03_gp164;old_locus_tag=MPXV-M5312_HM12_Rivers-170 +NC_063383.1 RefSeq CDS 168230 168895 . + 0 ID=cds-YP_010377166.1;Parent=gene-NBT03_gp164;Dbxref=GenBank:YP_010377166.1,GeneID:72551580;Name=OPG195;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp171%3B shope fibroma virus T4 protein-like%3B ER-localized apoptosis regulator%3B similar to VACV-WR B10R and VACV-Cop B9R;gbkey=CDS;gene=OPG195;locus_tag=NBT03_gp164;product=Intracellular viral protein;protein_id=YP_010377166.1 +NC_063383.1 RefSeq sequence_feature 169001 169642 . + . ID=id-NC_063383.1:169001..169642;exon_number=OPG196;gbkey=misc_feature;number=OPG196 +NC_063383.1 RefSeq gene 169670 169972 . + . ID=gene-NBT03_gp165;Dbxref=GeneID:72551581;Name=OPG197;gbkey=Gene;gene=OPG197;gene_biotype=protein_coding;locus_tag=NBT03_gp165;old_locus_tag=MPXV-M5312_HM12_Rivers-171 +NC_063383.1 RefSeq CDS 169670 169972 . + 0 ID=cds-YP_010377167.1;Parent=gene-NBT03_gp165;Dbxref=GenBank:YP_010377167.1,GeneID:72551581;Name=OPG197;Note=Taxonomic breadth: chordopoxvirinae%3B Hypothetical protein%3B similar to VACV-Cop-B11R;gbkey=CDS;gene=OPG197;locus_tag=NBT03_gp165;product=CPXV205 protein;protein_id=YP_010377167.1 +NC_063383.1 RefSeq gene 170038 170886 . + . ID=gene-NBT03_gp166;Dbxref=GeneID:72551582;Name=OPG198;gbkey=Gene;gene=OPG198;gene_biotype=protein_coding;locus_tag=NBT03_gp166;old_locus_tag=MPXV-M5312_HM12_Rivers-172 +NC_063383.1 RefSeq CDS 170038 170886 . + 0 ID=cds-YP_010377168.1;Parent=gene-NBT03_gp166;Dbxref=GenBank:YP_010377168.1,GeneID:72551582;Name=OPG198;Note=Taxonomic breadth: poxviridae%3B protein kinase-like%3B similar to VACV-WR B11R and VACV-Cop B12R;gbkey=CDS;gene=OPG198;locus_tag=NBT03_gp166;product=Ser/thr kinase;protein_id=YP_010377168.1 +NC_063383.1 RefSeq gene 170988 172022 . + . ID=gene-NBT03_gp167;Dbxref=GeneID:72551583;Name=OPG199;gbkey=Gene;gene=OPG199;gene_biotype=protein_coding;locus_tag=NBT03_gp167;old_locus_tag=MPXV-M5312_HM12_Rivers-173 +NC_063383.1 RefSeq CDS 170988 172022 . + 0 ID=cds-YP_010377169.1;Parent=gene-NBT03_gp167;Dbxref=GenBank:YP_010377169.1,GeneID:72551583;Name=OPG199;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp173%3B serine protease inhibitor-like%2C SPI-2%3B inhibition of the IL-1b converting enzyme%3B apoptosis inhibition%3B Serpin 1%2C2%2C3%3B similar to VACV-WR B12R and VACV-Cop K2L;gbkey=CDS;gene=OPG199;locus_tag=NBT03_gp167;product=Serpin;protein_id=YP_010377169.1 +NC_063383.1 RefSeq gene 172150 172599 . + . ID=gene-NBT03_gp168;Dbxref=GeneID:72551584;Name=OPG200;gbkey=Gene;gene=OPG200;gene_biotype=protein_coding;locus_tag=NBT03_gp168;old_locus_tag=MPXV-M5312_HM12_Rivers-174 +NC_063383.1 RefSeq CDS 172150 172599 . + 0 ID=cds-YP_010377170.1;Parent=gene-NBT03_gp168;Dbxref=GenBank:YP_010377170.1,GeneID:72551584;Name=OPG200;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp174%3B Hypothetical protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR B13R and VACV-Cop C16L and B15R;gbkey=CDS;gene=OPG200;locus_tag=NBT03_gp168;product=Bcl-2-like protein;protein_id=YP_010377170.1 +NC_063383.1 RefSeq sequence_feature 172685 173697 . + . ID=id-NC_063383.1:172685..173697;exon_number=OPG201;gbkey=misc_feature;number=OPG201 +NC_063383.1 RefSeq sequence_feature 173744 174187 . - . ID=id-NC_063383.1:173744..174187;exon_number=OPG202;gbkey=misc_feature;number=OPG202 +NC_063383.1 RefSeq sequence_feature 174328 174456 . + . ID=id-NC_063383.1:174328..174456;exon_number=OPG203;gbkey=misc_feature;number=OPG203 +NC_063383.1 RefSeq gene 174532 175587 . + . ID=gene-NBT03_gp169;Dbxref=GeneID:72551585;Name=OPG204;gbkey=Gene;gene=OPG204;gene_biotype=protein_coding;locus_tag=NBT03_gp169;old_locus_tag=MPXV-M5312_HM12_Rivers-177 +NC_063383.1 RefSeq CDS 174532 175587 . + 0 ID=cds-YP_010377172.1;Parent=gene-NBT03_gp169;Dbxref=GenBank:YP_010377172.1,GeneID:72551585;Name=OPG204;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp177%3B cell surface antigen and secreted IFN-a%3B IFN-alpha/beta receptor glycoprotein%3B similar to VACV-WR B16R and VACV-Cop B19R;gbkey=CDS;gene=OPG204;locus_tag=NBT03_gp169;product=IFN-alpha/beta-receptor-like secreted glycoprotein;protein_id=YP_010377172.1 +NC_063383.1 RefSeq gene 175656 178019 . + . ID=gene-NBT03_gp170;Dbxref=GeneID:72551586;Name=OPG205;gbkey=Gene;gene=OPG205;gene_biotype=protein_coding;locus_tag=NBT03_gp170;old_locus_tag=MPXV-M5312_HM12_Rivers-178 +NC_063383.1 RefSeq CDS 175656 178019 . + 0 ID=cds-YP_010377173.1;Parent=gene-NBT03_gp170;Dbxref=GenBank:YP_010377173.1,GeneID:72551586;Name=OPG205;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp178%3B ankyrin-like%3B similar to VACV-WR B17R and VACV-Cop B20R;gbkey=CDS;gene=OPG205;locus_tag=NBT03_gp170;product=Ankyrin repeat protein (44);protein_id=YP_010377173.1 +NC_063383.1 RefSeq sequence_feature 178118 178916 . + . ID=id-NC_063383.1:178118..178916;exon_number=OPG206;gbkey=misc_feature;number=OPG206 +NC_063383.1 RefSeq gene 179266 180339 . + . ID=gene-NBT03_gp171;Dbxref=GeneID:72551587;Name=OPG208;gbkey=Gene;gene=OPG208;gene_biotype=protein_coding;locus_tag=NBT03_gp171;old_locus_tag=MPXV-M5312_HM12_Rivers-180 +NC_063383.1 RefSeq CDS 179266 180339 . + 0 ID=cds-YP_010377174.1;Parent=gene-NBT03_gp171;Dbxref=GenBank:YP_010377174.1,GeneID:72551587;Name=OPG208;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp180%3B serine protease inhibitor-like%2C SPI-1%3B apoptosis inhibition%3B Serpin 1%2C2%2C3%3B Actual start may be at position 179%2C074%3B annotated start of ORF is missing approx. 17 AA compared to CPXVs%3B similar to VACV-WR B19R and VACV-Cop K2L;gbkey=CDS;gene=OPG208;locus_tag=NBT03_gp171;product=Serpin;protein_id=YP_010377174.1 +NC_063383.1 RefSeq gene 180518 181090 . + . ID=gene-NBT03_gp172;Dbxref=GeneID:72551588;Name=OPG209;gbkey=Gene;gene=OPG209;gene_biotype=protein_coding;locus_tag=NBT03_gp172;old_locus_tag=MPXV-M5312_HM12_Rivers-181 +NC_063383.1 RefSeq CDS 180518 181090 . + 0 ID=cds-YP_010377175.1;Parent=gene-NBT03_gp172;Dbxref=GenBank:YP_010377175.1,GeneID:72551588;Name=OPG209;Note=Old product: MPXVgp181%3B Hypothetical protein%3B similar to VACV-WR B20R and VACV-Cop C14L;gbkey=CDS;gene=OPG209;locus_tag=NBT03_gp172;product=Virulence protein;protein_id=YP_010377175.1 +NC_063383.1 RefSeq gene 181356 186998 . + . ID=gene-NBT03_gp173;Dbxref=GeneID:72551589;Name=OPG210;gbkey=Gene;gene=OPG210;gene_biotype=protein_coding;locus_tag=NBT03_gp173;old_locus_tag=MPXV-M5312_HM12_Rivers-182 +NC_063383.1 RefSeq CDS 181356 186998 . + 0 ID=cds-YP_010377176.1;Parent=gene-NBT03_gp173;Dbxref=GenBank:YP_010377176.1,GeneID:72551589;Name=OPG210;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp182%3B Surface glycoprotein%3B putative membrane-associated glycoprotein%3B cadherin-like domain%3B similar to VACV-WR B21R;gbkey=CDS;gene=OPG210;locus_tag=NBT03_gp173;product=B22R family protein;protein_id=YP_010377176.1 +NC_063383.1 RefSeq sequence_feature 187317 187743 . + . ID=id-NC_063383.1:187317..187743;exon_number=OPG212;gbkey=misc_feature;number=OPG212 +NC_063383.1 RefSeq sequence_feature 187822 188298 . + . ID=id-NC_063383.1:187822..188298;exon_number=OPG213;gbkey=misc_feature;number=OPG213 +NC_063383.1 RefSeq sequence_feature 188458 188963 . + . ID=id-NC_063383.1:188458..188963;exon_number=OPG214;gbkey=misc_feature;number=OPG214 +NC_063383.1 RefSeq gene 189199 189660 . + . ID=gene-NBT03_gp174;Dbxref=GeneID:72551590;Name=OPG005;gbkey=Gene;gene=OPG005;gene_biotype=protein_coding;locus_tag=NBT03_gp174;old_locus_tag=MPXV-M5312_HM12_Rivers-184 +NC_063383.1 RefSeq CDS 189199 189660 . + 0 ID=cds-YP_010377177.1;Parent=gene-NBT03_gp174;Dbxref=GenBank:YP_010377177.1,GeneID:72551590;Name=OPG005;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp185%3B VAC B15R-like%3B Hypothetical protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR N1R and VACV-Cop C16L and B22R;gbkey=CDS;gene=OPG005;locus_tag=NBT03_gp174;product=Bcl-2-like protein;protein_id=YP_010377177.1 +NC_063383.1 RefSeq gene 190410 190940 . + . ID=gene-NBT03_gp175;Dbxref=GeneID:72551591;Name=OPG016;gbkey=Gene;gene=OPG016;gene_biotype=protein_coding;locus_tag=NBT03_gp175;old_locus_tag=MPXV-M5312_HM12_Rivers-186 +NC_063383.1 RefSeq CDS 190410 190940 . + 0 ID=cds-YP_010377184.1;Parent=gene-NBT03_gp175;Dbxref=GenBank:YP_010377184.1,GeneID:72551591;Name=OPG016;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp187%3B similar to VACV-WR N3R;gbkey=CDS;gene=OPG016;locus_tag=NBT03_gp175;product=Brix domain protein;protein_id=YP_010377184.1 +NC_063383.1 RefSeq long_terminal_repeat 190788 197209 . + . ID=id-NC_063383.1:190788..197209;gbkey=repeat_region;rpt_type=long_terminal_repeat +NC_063383.1 RefSeq gene 191054 192367 . + . ID=gene-NBT03_gp176;Dbxref=GeneID:72551592;Name=OPG015_dup;gbkey=Gene;gene=OPG015_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp176;old_locus_tag=MPXV-M5312_HM12_Rivers-187 +NC_063383.1 RefSeq CDS 191054 192367 . + 0 ID=cds-YP_010377179.1;Parent=gene-NBT03_gp176;Dbxref=GenBank:YP_010377179.1,GeneID:72551592;Name=OPG015_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp188%3B ankyrin-like%3B Ankyrin (CPXV-017)%3B similar to VACV-WR N4R;gbkey=CDS;gene=OPG015_dup;locus_tag=NBT03_gp176;product=Ankyrin repeat protein (39);protein_id=YP_010377179.1 +NC_063383.1 RefSeq gene 192603 194369 . + . ID=gene-NBT03_gp177;Dbxref=GeneID:72551593;Name=OPG003_dup;gbkey=Gene;gene=OPG003_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp177;old_locus_tag=MPXV-M5312_HM12_Rivers-188 +NC_063383.1 RefSeq CDS 192603 194369 . + 0 ID=cds-YP_010377180.1;Parent=gene-NBT03_gp177;Dbxref=GenBank:YP_010377180.1,GeneID:72551593;Name=OPG003_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp189%3B ankyrin-like%3B similar to VACV-WR J1R and VACV-Cop C19L;gbkey=CDS;gene=OPG003_dup;locus_tag=NBT03_gp177;product=Ankyrin repeat protein (25);protein_id=YP_010377180.1 +NC_063383.1 RefSeq gene 194459 195508 . + . ID=gene-NBT03_gp178;Dbxref=GeneID:72551594;Name=OPG002_dup;gbkey=Gene;gene=OPG002_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp178;old_locus_tag=MPXV-M5312_HM12_Rivers-189 +NC_063383.1 RefSeq CDS 194459 195508 . + 0 ID=cds-YP_010377181.1;Parent=gene-NBT03_gp178;Dbxref=GenBank:YP_010377181.1,GeneID:72551594;Name=OPG002_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp190%3B secreted TNF binding protein%3B TNF receptor (CrmB)%3B similar to VACV-WR J2R and VACV-Cop C22L;gbkey=CDS;gene=OPG002_dup;locus_tag=NBT03_gp178;product=Crm-B secreted TNF-alpha-receptor-like protein;protein_id=YP_010377181.1 +NC_063383.1 RefSeq gene 195635 196375 . + . ID=gene-NBT03_gp179;Dbxref=GeneID:72551595;Name=OPG001_dup;gbkey=Gene;gene=OPG001_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp179;old_locus_tag=MPXV-M5312_HM12_Rivers-190 +NC_063383.1 RefSeq CDS 195635 196375 . + 0 ID=cds-YP_010377182.1;Parent=gene-NBT03_gp179;Dbxref=GenBank:YP_010377182.1,GeneID:72551595;Name=OPG001_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp191%3B Chemokine binding protein (Cop-C23L)%3B most abundant secreted protein%3B CC-chemokine binding protein%3B similar to VACV-WR J3R and VACV-Cop C23L and B29R;gbkey=CDS;gene=OPG001_dup;locus_tag=NBT03_gp179;product=Chemokine binding protein;protein_id=YP_010377182.1 diff --git a/data_output/nextstrain/mpox/clade-iib/unreleased/pathogen.json b/data_output/nextstrain/mpox/clade-iib/unreleased/pathogen.json new file mode 100644 index 00000000..934126a1 --- /dev/null +++ b/data_output/nextstrain/mpox/clade-iib/unreleased/pathogen.json @@ -0,0 +1,92 @@ +{ + "alignmentParams": { + "allowedMismatches": 5, + "excessBandwidth": 40, + "gapAlignmentSide": "left", + "minSeedCover": 0.1, + "terminalBandwidth": 200, + "windowSize": 30 + }, + "attributes": { + "name": "Mpox virus (Clade IIb)", + "reference accession": "NC_063383.1", + "reference name": "MPXV-M5312_HM12_Rivers" + }, + "compatibility": { + "cli": "3.0.0-alpha.0", + "web": "3.0.0-alpha.0" + }, + "deprecated": false, + "enabled": true, + "experimental": false, + "files": { + "changelog": "CHANGELOG.md", + "examples": "sequences.fasta", + "genomeAnnotation": "genome_annotation.gff3", + "pathogenJson": "pathogen.json", + "readme": "README.md", + "reference": "reference.fasta", + "treeJson": "tree.json" + }, + "official": true, + "qc": { + "frameShifts": { + "enabled": true, + "ignoredFrameShifts": [ + { + "codonRange": { + "begin": 289, + "end": 346 + }, + "geneName": "OPG174" + } + ], + "scoreWeight": 20 + }, + "missingData": { + "enabled": true, + "missingDataThreshold": 20000, + "scoreBias": 1000 + }, + "mixedSites": { + "enabled": true, + "mixedSitesThreshold": 40 + }, + "privateMutations": { + "cutoff": 50, + "enabled": true, + "typical": 5, + "weightLabeledSubstitutions": 6, + "weightReversionSubstitutions": 6, + "weightUnlabeledSubstitutions": 1 + }, + "snpClusters": { + "clusterCutOff": 5, + "enabled": true, + "scoreWeight": 20, + "windowSize": 100 + }, + "stopCodons": { + "enabled": true, + "ignoredStopCodons": [ + { + "codon": 187, + "geneName": "OPG015_dup" + }, + { + "codon": 187, + "geneName": "OPG015" + }, + { + "codon": 21, + "geneName": "OPG176" + } + ], + "scoreWeight": 40 + } + }, + "schemaVersion": "3.0.0", + "version": { + "tag": "unreleased" + } +} diff --git a/data_output/nextstrain/mpox/clade-iib/unreleased/reference.fasta b/data_output/nextstrain/mpox/clade-iib/unreleased/reference.fasta new file mode 100644 index 00000000..0f1d13ac --- /dev/null +++ b/data_output/nextstrain/mpox/clade-iib/unreleased/reference.fasta @@ -0,0 +1,2 @@ +>NC_063383.1 Monkeypox virus, complete genome +ATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTAACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATTTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAAACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACAAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTTGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAAT diff --git a/data_output/nextstrain/mpox/clade-iib/unreleased/sequences.fasta b/data_output/nextstrain/mpox/clade-iib/unreleased/sequences.fasta new file mode 100644 index 00000000..1701fd6f --- /dev/null +++ b/data_output/nextstrain/mpox/clade-iib/unreleased/sequences.fasta @@ -0,0 +1,10 @@ +>MPXV_USA_2022_MA001 | ON563414.2 +TATTATATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCRAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTTGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGAGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGAGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATATAATA +>Monkeypox/PT0001/2022|sampling_date_20220504_v2 +CGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGNAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACNTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTNAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACNGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCNTTTGAGAAGACAATAATATCCTNGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTANGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACNGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTNAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAANNGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTANGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCNNNTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTANCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTAACTAACTTATGANTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAANACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATANTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATNAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATNAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATNCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCNAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTNNAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATNAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCNTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATNAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTANTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCNTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCNNTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCNGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTNNTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTNGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCANTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTNAATACATCTATATTANGATTTGATGTTGTCGCGTANTNNTCTACAATATTAATACCANTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTNAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAANNNATTNATATTTTTATAGTCGACTGACGACAATAACAAAATNACNACATCNTTTTTGANNNNNNNNNNNTTTNNNNTAACGTATGCCTTTNNTGGANNNTCACCATCATACNCNNATAATGGATTTGCACCACTTTCTATTAATGATTNTNNACTACTGGCANCGATGTTAAATGNNTTACAACTATCATAGNGTATNNTATCGTTAACCATGATTGGTTGTTGATGTTATCACANNTTTTTGGTNNNTTTCATTTCAGNTANNTATGGATTTAGCACGTTTNGGAAGCANGNGCTCNNATGATTTCAGTACTGTAGTGTCAGTNNTATTAGTTTCGNTCAGATCAATGTCTAGATCTATAGAATCNAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCNTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTAGTATAAAATTCTATATTCAAATTATCATGCGANNTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAANNAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGNTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCNTGTAATCATTCGAAATAANTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGNGGAATCAGTTANGAANAAAAAATTATCTGTCATCATCATCATCTATTNGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTNGATACATCACGACCNTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCNTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAANTTTTTATGGTATAGATCCNNTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTANCTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCNTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTNGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATNAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTANGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTANGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCNAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCNAATACTTNGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAANNAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAANCNGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTNGATCTGCGCNGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCNAAACAACATATACACATTTAATNAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTANGAGCCATCATTTCGGCTATCGACTTAATATNCCTCTTGTTTTCGATAGAAAATCTANNGAGNTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGNGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCNTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGNAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTNAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATNCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCNTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGNAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAANTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCNTTTTAAGCCAAAATATGGAAGCGAATGATCCGGNAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCNTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTNNTTCCACTGTCCAAAATGATGNCTCTGCCNTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAANTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTNCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTNNAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCNCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAANTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGNTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGNTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTNAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCNAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTNAAAAGTTGTCACAACAGGGTNGTTCGTAGATTTTANNGTATAACNGAGACATNNNTNNAAAGATAAACTTTNTGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTNNNTCGGTATCTACTTTATCTGCCGAATACAGTGCTNNNGNNAAAATTATAATNTTTNNNCTTTCGTATTCGTAATTNGTTCNCTTTTCATGTTCGNAAAAGTGAAACNTGCGGTTAAAATNGTTTATAACATTAATATTACTGTTNNNNNCTGNCGGATNAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTNNNNTCGTTAAACGCCTTTAGNAAAACTNNNGAAGAATATCTCAATGNGAGTTCCTGACCATCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTCATCTNCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCNNCGTAGTTTCCATGGGACTATANNNNNNTGTNNCCTNGAATNNNNNNTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCNNCCTGTAGATATGTGATNAAAATCGTCGTTTATAGGATAAANNCGTTTATCNNTTTGTTGNNNAAAGGATGAATTAATGTAATCATTCNNNTCTATCTTTAGTAGTGNTTCCNTATTAAAATTNTTAAAATAATTTAACAATCTAACTGACGGAGCCCNNNNTTNGTGTNAATCTAATTGGGACATTANNTTGTTAAAATATAAANNNTCTCCTAATATAACAGTATCTGATAANCTATNGGGAGNCATCCATTGATATTCANGGGATGAATCATTNGNAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCNTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTNCAATTGTTGCCTGTATTGTATTANAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTANGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCANTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAANCANNAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACNATGNNCGGNTTAATGTNNTATGTAACATTGAGTAAATNCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATNCAAACAATGTTTCTANCGGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNNCGAATCAGTAACTATGTTCANNTTTTTANNNGTANGACGTCTAGCCAGTATNGANNAGGATTTTCNAGATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTCTATGAGTTGTTNCAATAAATTATTTGTTGTGACTGCGTTCAAGNCATAAATTANNTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCNCTGATAGCAGTTTNAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCNTTTGTACCANTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTNAGAACATGTCTTCTATTCTNGAAAACGAAAACATCCTNNATNGACTCATTAAAACTTNTAACGNNCCNGNTTGTGTTTCNAATGCCTNNNNCAAGGANNTCAAGGATGCCATAGATNNTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGANTTTTTTATTAAATCAAATNGTCGGCTCTCTGGTTTACTACCCCAANGATAACAATAGTCTTGTAAAGATANNNNNNNNNNNNNNNNNNNNNNNNCCATCCAAATAANCCTANNANCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCNTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAANTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAANTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATANTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTNAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACANTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACNTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTANGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGNATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTNCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCNNNAAAAAATCNTTTTTNATTNNTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCNTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACNTATTCAGAGTTGTTGTTCAAATAGATNCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGNNNTGCGGACATTAAACGATTTGATGAGTTAGATATTAATNACNNNNATATATCTAATATAATTTATGAGGTGAACGATNNNACATTAGATACAATGGATGATATNAAGAAGTGTCAAATCNTTAACGAGGATACGNNGTATTATGTTAAGGAATACAATACATACCTGNTTTTGCACNAGTCNGATCCCATGGTCNNAGAGAACGGAATACTAAAGAAACTGTCATCNATAAAATCCAAGAGTAGACGGCTNNACTTGNTTAGCNAAAACATTNNNAANNNNTATTTNNACGGACAATTNGCTCGTCTAGGTCNNNTGTTNGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGNGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAANCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGNTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTNNAGAGATAATCTATATCATGTAGAAGAATTCTTNGATNAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTGATAAATGNNNACCGTTGCNACANNTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATANTTTAACCTGATGTNNTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAANNNGTAGGATATNAATATTATGGCCGCAACCGTTCCGCGNTTTGACGANNTGTANAAAAATGCACAAAGAAGAATTNTAGATCNAGNAACANNTTTNNGTAGAGGTCTNNNTAGACCGTTAATGNAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCNNTATAAANGTCCTATTNNCGTATATGAAGNAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTNCGGTAGATACGTATCATATCTTNNAAAGTTTTCNNNCCTTCCAACAAACGAGTTTATTANNNNNTTANTATTGACCTCCATCCCTATCTNNNATATCNTATTCTNGTTTNNAANNACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCNTGCGTTGGCTANGTATATACATCAAACAGGAGACTATNNGNCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTNGTCCCGTTCCAATAGGTATCNAAGATATAGATCACCCTAATCNTAGTAGAGCANNAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGNTTTTATTGNTTTACGTACCTGGGTATTCAATTACTACNNNNNNTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACNAAGAGCGACGTACAANTNTNNTAAATTATTTTATGCTTCNNAAAATGTAGGTCTTGAACCAAACATTCTTTGNAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATNGTTTNNAGNAAACTNNNTAAAATATTCTTTGATTGCTGCCGAGNTTAAAACTTNTATCGATAATTGTTTCNNNNGTTTTAATATTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAACCAAATACATATTANGGTTATCTGCGGATTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTATTAATCNGTCGTTCNAACTCCTTTGNTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCNGTNAACACNGAGTCGGTANNTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATNTCTATCGTCCATATAAAATGGATTACTTAATGTATTNGCNAACCGTAACATACCGTTNGATNNCTCNGNTCCATTTAGTACCNANNCNAGATACAATATCATTCTACGTCCTATGGANNTGCAACTCTTAGCCNAAGNGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTANNNTGNTTTAANNNNNTTTTATATNNNNNNNNNTNNNCCNAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTNNTGAAGCAAGAGTTGATTATTTATNNNTTCTTNCNATCTNTTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATNNNNNNNNNNNNNNNNNNNNNNNNNGATACAGACNNNTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGNTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCNNAGTATNGTCACCGATGAACGTCATTNNNNTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTNGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGANTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATNATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCNTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACANNNNNTCATTAATGANNGTAAACNNNAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGANCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTNAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGNTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATNTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTANTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCNAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTNGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACANTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGNAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATNTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTNCCCTGTCTGCAGCCATTTTTANGNTCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCNCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATNCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCNTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTNCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCNCAACATTNGAATAATACCGTTTGATATACCATTNGTACCNGAGATATAGCTTCCACTNGCACGAATATNNNTAATTGATAGACCTATTNCCCCTNCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCNATGCTATCATCGATCATGTTAAGTNGAAAACAGCTAGACATTTGGTGACGNGTNGTTNCCGCATTNAANAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAANTTTTAAAACCAAAATAGTTGTANGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCNGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTANNATGGCGGTGCCAGAAATTACCATCNAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTNNNTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTNNTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCNTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCNTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCNGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTNANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAATATTTCGATGATATACGGTAGTCTCTCNTTCNGACTTNTATAGCNTATTNCACAATACGAGTCATTATATACNCCNNAAAANNNAATNNNTAGTATNAAATCNGTATCGAATGGNNAAAACGAAATTATCGATATAGGNNTAGAANCNNGAACATTGAACGTATTAATACTTAATNNTTTTTCANNNNNAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTNNGACTTGATAGATATTAANGACGAATTGNAAATTANTTTTATNACCACNNGTGNNTCAGGANCNTNGTCGANNNCAGTTAACCAACCGAATGGAGTANNNNAAATATCATTAATATATGCNCTAGATATTAGTANNNNNNTTAANNCTTTGATTATCATCTNNTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGNNCATCCTCCNGAGTATTAATNGGTTTAGTAAACAGTCCANCGTTGCNATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCNNNCGNTTAAAGATNNNACCTCATCTAACGGAGACAANNTTNNNGTAGGNTTTNNAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACNTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCANTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGNAAAAGAATAGAAATNAAAATTATTATAATGGTGGAATTCAGTTNGAATATTGNCTCCNGAGTCATNAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTNCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACNTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCNTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGNGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGNAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTANGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCNAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCNAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGNAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTANTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCNTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACNTTTGTAGAATATTATTCNGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTNAAAATCAAAATCTAATGACCACATCNNTTTTTAGAGATGNAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGNAAAAANTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCNATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGNTTTGATCTACTATACTTTNAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTNCTTCGGCATTTCNNTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGANNCGTCTNNGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTANGGGTATACTTCNATAAGGTTTNTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTNGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGNGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTANNTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTANAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTNTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCNAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCNTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTNAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGNAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCNNGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCNGAAGTTAAAACTTTATCATCTNNTATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGNAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTNGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTNATTTGAATCCATCGATAGAAAAACANNTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTNGATAGATTTTTTNNANGATATCTTAGTGCNAAAGTATACATGTTAGAGAATATTCNAGTTATGAAAATAGNAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATNAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGNGTATTTNTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTANTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTNTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATANTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTNGCAACAATTGTAGATACCATTAATCACTGATTCCNNTTTCGATNNNGGACAATAGCACAATTGTTTAGCNNTNGACTCTANNTATNNAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATNAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTNTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCNTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTNCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAANCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACNGCACCCAATTGCTGTCGCACNTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGNTGATTTATTCGACTGGTGTCANGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTANNTCTCTTNNTNATATGGATACTAATTGTAGCTATTTAAATGNGTGCCGCANCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTNAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGNNAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTANNTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCNGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTANTAATCTTCTTTGGGCACATATACCAGTNTACCAGGTTCTNNNAACCTANTTACTGGTGCTCCTGTAGNATACNNNNNTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTANNACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGNAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCNGGGTTAATCTCACAACTTTACTGNTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATNCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCNGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCNAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTNAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGNAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATANTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGNAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATNCCACAGAACTAATGTATATTCTAGGTACTTNTGGACAACNNAGGATAGATNNNGAANCAGCAGAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATGGTTCTTCCAGGTGNCGCCAACANGGGNNANNTTAGTAAATTCNAGATTCCTATCTCTGACTATACGGGATATAACGACNTCAATCAAACNAAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTAGTTACGANNCAGAATCANTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTANNAGAGNNNCGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCNTAAAAAGTCAGAACCTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAANGAAACTATCTGATAAGATATCTTCTCNAAAGATCNAGGAGATAGNAGAAACNGNAGACNTTTAATTCTTATCNNNAACATANTTTTCNATGATCTGTCTTTTAAACGATNGATTTTNCACAAATGCGCCTCTCNANTCCCTCATAGAATGATNNACGNATNNANNNNATAGCATAGGTNATGANNCCTTATTTTTAGACATTAGATATNNNAAAATCATAGCCCNNCTTCTATTTACTNCTGCAACACAATGAACCAACACNGGCTCGNTTNGTTGATCACATNNNGANAAGAAGGCGGTCNCNTCGTCAAAANNNTTACTAATATCNGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATNNACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGNCAAGACATCAACACTTATANTTTTTGTTATTATATTGGCAATTAGTNNGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACNAGATATATGCGAATNAAAAATACNGTTAACGATTNNAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTNAAAAGGCGGCNAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCNAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCNANTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTNAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCNTTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATNCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTNAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACNTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTNAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAANTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACNTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTNNNNAAAAGATCNTNCAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATNAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATNCTATATATGNAAAAATAGCAACCNGTGTTTGATCATNCGCGTCAATATTCTGTTCTATCGTANTNTANAACAATCTTATATCNTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATANTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTNGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAANTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACNAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAANTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCNAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTNGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTNAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTNAGNTTNNATTATCTNNNGTACATGGTCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGATANNATAGTNNNNGNNAAGAAATCATTAGTGACGGAAAATCGTCTTCACNAAGAATGCTTGTTGAGACNATCAACAGAGGAACGTCATATNTTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAANTTTACGATAGACTTTAAGCTAAAATATTTTCTANGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCNCGCTATTAATCATCCNAAGTCAAGGCCTAATANATCTCTNGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTNTTTCTCCACCTATTAACGCACCTATAAAGACNTTTATGTTGCCTAAACAAGATATAGTAGGTCTNGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGNTACATCAAAAGGGTTGNATTGTTANTTTANACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTNAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTNGAGAGTCGTCTATCTTTATAGAGTATANNAAATTTACCAACGATANNNGCTTTNNNAAAGAATATGGTTCTNGTNNGATTGTGTNNTATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGNNATTNAGTNNGTTGTNGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCNAAGCATCAAAATAGGAGATGTCTTTANCGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGNAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCNNTAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCNNNGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCNANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAACNAAGTNNAAAGNTTATTANNNGCGCATCTACAATGGAAGATAGACCGTCTACAANAAACTTTTTCGAACTAAATAGAGGAGCCATTAAANNTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCNTTTCTNNNNNGTNAANAATANNATGGTATNGGTTCTGNTATNCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATNAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGNNATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCNAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTANTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTNNGAAATCACAATGACTTTATCAGATCNAAATTAACAAAATTAAANGAGCATGTANNTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTNAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTNGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATNGAAACAGCCGCTTAGAAATAAACGAGTANNTGTGTGTGGTATAGATCCGTATCCNAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACNAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTANGAGAAACAAAAAGTCACGCGATTTACTNGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATANGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGNAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTNGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAANCCTTGATAACNAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTNAAAAATATACNNGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGNAAAATAGAGAGCTGTATGNNAAAACATTATCTAGTTGNTTATGTGGTGCTACNNNANGATGTTTAACATTCNNNNTTGGAGAAACCGCAANNNNGAAGTCGACAACCAAACGTTTGTTAAAGTNNNCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAANTTTAACAGATGTATTNGANAAAGGACCTAATCCATTTATCGCTAATATGCATTTNNAAAGATCTGTANTCNGTAGNNNACNACCTGNTTTTGCATGTANNGGATCNAAGNNNNTTANATCNNNNNNNNNTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTNCAATAAAATTAATAATANAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATNAGAAGAATTGCCGTCGTGCGATTCAGAACACACNTTTCTCAACCTTCTGGTNNAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACNAAAAATATCATATTNCTATTATGAAACTATATCCTACACCGGAAGAGATTNCGGACTTTGCNTTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTNCNTTAATGACGGACCTCTNNNAAAAGGGATATATATTGTACGATAATGTGGTTANTCTTCCGTTGANTNCTNNNCAACAGAAAATATCCAAGTATTTTAATTNNNNNCTATTTGGNNACGATANNNANAGCTNNATCAATAGACATANGAANNNTNCCAATGTTAGTGATGAATATCTGCANNATATATTCATANNNGATANNTNATCTCCGTAAATATATGCCATATATTTATAGAATATATCACANATCTAAATGAATACCNGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGNTTATCTAGTTNGAANTATCATAGATGAGAACNGAAGCGTGTTATTGTTCCNNATTATNNGATCGGGTAAAACAATAATCGCTTTGTTGTTNNNCTTGGTAGCTTNCAGATTTNNAAAGGTTTACANTTTAGTANCGAACATCAACATCTTAAAAATTTTCAATTATAATATNGGTGTAGCTATGAACNTGTTTAATGACGAATTCATAGCTGNNNATATNNTTATTCATTCCACAACAAGNTTTTATTCTCTTAATTATAACGATAACGTNATTAATTATAACNGATTNNNNCNCTACAATAACTCTANTTTTATCGTTGATGAGGCACATNATATTTTTNGGAATAANNNNNNNGNACTTATGACCGTGATNNNAAATAAAAACAAGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTGAGATTATTAGTCGTGGTNNNNAAGNAATTCAGACACTTCTTAACGAACNCNGAGNGANNNTACNCNNNNATTTGNNTANNNNAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACNNNAGTAGTATATTGTCACATGTCTAAACNNCANNAGAAAGATTANNNGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATNAAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCACTTTNNNNNCTTCTNTAATTCNANATATGGTGGATTGGTAATTAAATATATCATGCTCNNNAATGGATATTCTGAATATAATGGTTCTCANGGNNCTAATCCACATATGATAAACGGCAAACCNAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTNTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCNTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCNTTGACATCNAAAANCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATAATTNTCGTATTAAGTATAACGACTNCAAGTTACTTNAAATGGTTACATCAGTTATAAAAAATAAANAAGACGCTANGAATTACATNNNNGATATTGTAAACGGTCACTTCTTTGTATCGAATNAAGTATTTGATAANNNNCTTTTATACAAATACGAAAACGATATTANTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTNGGGAGTTAANTNNNGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGNNATATAAAGAAATAAATGTCGAGCNTTGTTACCAATGGATATCTTCCAGTTACATTNGAACNNCATGAGNTGACGTTAGACATNAAAACTAATATTANGAATGCCGTATATAAGGCGTATNTCCATAGNNNAATNNGTGGTNAAATGGCCAAGNAAATAGAAATTCGTGAAGACGTGGAATTANNNNTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCNNNTGNANTAACCTACGCATATTATCACGTTNGGGATATAGTCAGAGGAACANNAAACATCGAAGATGAATCNAATGTAACTATTCANNNNNNAGATTTAANCTGTAAACTAAGTAGAGATTCNGGNACTGTATCATTTAGCGATTCNNAGTACNGNNTTTTTCGAAATGNNAANGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTNTCGCGAATATCGTTGACTNANAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTNCCTTCGATATATTTTTGATAATATGNAAAACATGCNNCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCNNATAATCTNCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTNTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCNGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTNGNAAAANTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACANTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGNTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAANCCTCCACTTATATATCCTCCTTTNAAATTAATCCTTACTAGTTTTCCAGTATTCTNGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCANAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGNGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTANTTNCNAGGATGACTNTCAAATTATTACNCNCACGGCANNNGNTAACCAATGCCTATNGTNTCANAAACNANTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGNAACAGACGAGATAGNTTTNTCTATTNNNAAATAATTAGAACTNNAAACATGTATNGAAAGNAACGATTATTTCTGAATTATTNCAATTATTTGAACAAACAGNNNNGAAGTATACTATCGTCANNTTTTTCTCNNGNTNCANNTACTGCTGATAATGATAGAATAAACGCNATTTATCCNNGTGGTATACCCAAAANNGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGNNAATATAGACANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAAGATACCATTATTAACAAANTTTTTGAGGTAATTTTCTTTGTTNGACGAATATNTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAANNTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTNAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATANTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCNTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCNTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCNGCGAGTTTAGCCNTTTGATAAATCTCTTCTTGCNTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTNCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGNTTTTTAACGCAATGGTCTTAGATNAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTNAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCNNGGATCTTNTATCAAAGCCNTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGNNNNNATATACAGTAGTCATTGNTTTACCGACACCTGNTTCATGGAACAATNAAAGAGAATGCATACTGTCTAATNCTNNGAAAACTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTNNACGGGCATATTAGTAGTTCTGCGTAAGGCATAANCGATATAGGCNNNNNGTGATTTACTCATTTATNNGNGNTNAGTAATAACTATGTTTTNAAAATCNNNNCAGTAGTTTNNCTAGNCTTNTCTNATGTNNNNTTTCGATACNTTTTGAATNNNAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTNGTATACTCTATTCGAAAACTCTAAGAACTTATTAATNAATTNCGTATCCACTGGATCGTTTNAAATNNTAAATTGAACAGTGTTCACATCCTTNCAAGACGAAGACTTAGTGNNGGACTTAACATGAGACATAAATNAATNCAAANTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCNTTCNNCCAACTANCGCNTACGCATTTTAACAGTCNAANANTTTTAAAGAGACTACAATATANTCTCNTNGTATCGATTNNACCTCTACCGAATAGAGTNGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAANGTTAACATCTTATAATCGCTAATGTATNGATTGNTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTNCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACNGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACANCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTNAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGNGAGTGCTTCTTCTTTANCGGGCTTAAAGACTGCTTTNNGTGCTGAAATAACCACATCTGGANNACTTACTNGCNNAGCCATTTAATTACGGAACTANTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACNAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGNTTTTTAGATCTCATATGTGCTNAAAAGTTTTCCCATACTAATTNGTTACTATTATTTTTCGTATANTTTTTAACAGTTTGAGGNTTTAGANTTTTAGTTACNGAAGTGATATCGAATATTTTATCCNAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCNAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCNTTTCTGTACTCNGATTCAGNTTNTCATCNTTTANNTGATTGATTATTTNAAAGACTAACTTATAANNCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGANNTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTNCAGAACATTGATGAGACAATAATCTCCGCAATACATTNNTCAAATGAATAAGTTTATTAGACACNNGGAAGNTTGNNNNNTTTTGTACCTTTGTACATTTTTGAAATACNGACTNNCNAAAAATACAATATTCATATCCTTGTTCAGATACNNTACCNNNATGTCTANAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTNCAATATTTTATATNAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATANTTTTANTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATNTTTTTCGTACCAACTCNTTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTANAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTANNTCNCGGATTGNAAACAGAAAGAGGATCGTACATCCAAGGTCCNTTTTCTGTAAATAGAATCGTATAATGTNCCTTCAAGAAGATATCNGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTANCCTATACATGATACCGTTTAGCNTGATTTCTGGTGATNCGTCAATCGGAGTATCATCTATNAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATANNCNTATTCTGANNTNNTTCTACATNAAACATCATTGCTCCATTAACGATAACANNNGAATGAACAGCNCTACCCATCACNNTAGTTCCCAATGGATCAANNTGTGTAACTNCAGAACATCTTCCATAGCCTATGTTANGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATNGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGNGTNCATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATNGGAAAGGAGTNGAAATNNCTCGNTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATNCTGAATAGTAAAGNTAGATNNNTCATACTTGTTAGTAGTTAGATATTNNGCAATTGNANTCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTACGTTTAGGTTTGGTACGTTGATTTCNANNCCCTGCTGATATNAAGTCATCGTCTACAATTTNGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAANNGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTNAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGANTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCNGNCTGAAGTTGACGCATATCNTTTTCAACACTNGACATGAGATCCNTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTNGATTTGGANTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGNNCATACAGTGGCCACAATANGAGGTTGAAGAGGTGTAACCGTTNGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCNTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTNGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATANGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTNCATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCNTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCANNNNNNNNNNNNNNNNNNNCATCCACGNTTTGATAAATCTATCNTTANCTNNTGAAATAACGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGATNACANNTTTTGTAAATGTAANGTANTTAGACGANAGATCTTCGTTNNAAAGTTTTNCATNTATNNNNAATNCATCGGTTGTTAACACCATTCCCGCGTCAGANTGAATANGAGTTTGAATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGATGNAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTNGAGGCCTCCGTAGAACTANGGGANGTAAATANAGATCNAACAACACCTATGATAAAGGAGAATANCGGNTTTATATCCCGTAGTNGNCGTCTATTNNCCCATANNNNTNNGGATNNNNNGANAAAACNNNCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAANTCAACTCNNNAGTATCCATCATCCAAGNAAAACNCGGATACCAGTCTNGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAGTTCANTATCTGAAATAACNNATAGATTTTATNNNNTTAATCNAAAATCTGATCTTGTTCAATGGNGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGNAAATGATTCACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAGCAAACGTGATNAGGATACGCTATTAAAACANTTTACTTATGACTGGNGTTAGAATTTATAGACGNNACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCNAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGANTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATNCTTCTNCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACNNNATGATTGTCTCAAGTCTNCAATCGTTTGTTTNGNNCGATTAGCTNCAGAGTNCAATGCTTGGCTAACTAGCATATTATTATCTTTNGAAATTGTATTCTTCAATGAGGCGTTTNNNATATCNNTGATTTCGTTAGTNATATTACAGTCTGANTNGGTTGTAATGTTATNCAACATATCNNNNNTGGATACGGTNCACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACNAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATANAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAANNCTNAANTAATCAANTTTTNNNNNNNGTTTTTACTACAACTAGTTTTCATCANNGTAGTGACGATGNNTTGTTTAGTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTGGTAACNTTGATAGCCGTAGATCTTTGTTCCNTCGCTAANNNGTTNANNAAATTAATAAAGAATTTGTTGTTTNNATTTATGTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGNTTATAATCTNATCATTGANNNNTACTCTGTTACCATTGTAATAAATTGGTACTCTATCNNNATCANCGACNNAGTACTGTTCATANATGATGAGATGTTTATATGTTGGCATANNNNNNNNNNNGACGTTTNGTAATGGCAANNNNNNNNNATTAACNNCATAATGTCTAGCAGCANCTGCGATGTTATAAGTGATGTCAAAGCNNGGTTNATCTTNNNNNNTTATATATTGTCTAACACCTATAANATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAANTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCNAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGNAAAAGCTGTGAGTATTAATAATANGGTTAGNTTNCGAACTAATGNNNNTTNGATGATNNNTAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACANTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACNAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCNNNAGGAAATATCATCACAACNNAATGAAGATCTNTTTCCAGNNNNNNNTTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTNGAGAGTTATTGATATCGGAACAACGTCAACAACNAGNAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTNTGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGNAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCNAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCNAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCNTTTTATTAGTGGGCATCTTTTTAGATGGTTTCNTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCNTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGNTTTTTAAGCTGTGGTGTAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTGCTTNNNCCACATAGAATAAANTAGCATTCCGACTGTGNNNATNNTACCNNGTATAAACGCCATAATACTNAATACTTNNCATGNNCGAGTNGGACTGGTAGACTTACTNNAGTCANNAAAGGCGANNATACACGNAAGAATCNNNAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTNCATTTAACTAATNAAAATTTTAAATCGCCGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTAATATCTANTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTNNNCNGCATNTTATAACTAACAGCAGCAACGGCTCGTAANNNNNTATCATTTACTAGACGAAAAGGTGGTNGGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACGTATAATGCNNNATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCNAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACANNATTTTGCCACGCTATCACTATCACCCNGGAGATAATCNTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCANNAGNATATTTTAAATNCTTAATATATTCANGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGNAAGAACTACATGGTTCTCCANGAATTAATACATATTGTTTAGCAAATTCAGGAACTATNAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTNCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTNAAAAAAATGACTTGTGGTCAGACCATAAGTCNTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATNAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTANTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATANTATTATTAATATTGCCAAGTTATCCGATCNNNAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCNGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACNATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCNAAAAAATAAAGTACATGATANGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTNGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACNNGTATTAAATAGAATATTTAANNNNCAAAATCNNNNNNAAGNTTNNNAGACGATCNNCATGCTGNGCNNGCCAGTGTATTANCCCTCATAGTATTAATATAATCCAATGATACNTTTGTGATGTNNGAAATNTTAACCAATTTAGACTGACAGGCANNACACGTCATACANNNATNATCGTCATCGATAANTNTAGTCNTGGGCTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCTGGTATANNGTCTCTATCTTTATNNCAATATAGTGTATCAACATCTTNNTTATTGACCTCNTTTATCTTNGAACATGGAATNGGNACATTTTTGTTAACNGCCACNNNTNCCNTAATTCCAGATGTTGTNAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTNTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTNAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAANNNNTTAGTCTGTACNAAAGTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGTAACTAATGTCNNGACGTCCATATCTGATTATTATGATGAGGTAAAAAANAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAANGGTAAAAATATGGTAGAACTTGGATCTGGAAACTNTTTTCAAATACCGGATNAGATTCNAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGANGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATNGTATAGGAGATAATNTTTTTATTCCTAGCGTTATAACAAAATCAGGNAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATNGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATNGACACTANNNGACGAGACTANTATGNNNNTGNNNANTANNNNNNNNNNGTTGGTATTGCAGGCNNNAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAANNNTCGATGAGTTAGTTGATGAGATTAATAAATCNNNAACTNTNAAACGAAAAANNAAAAACCAANCAGTATTTGATTTNAGNAGAGAATGNTTGGGATATCCNNNAGCNGANTTTATAACNNNAGTNNNTAACATNNNGTTCNNANNAGNAAATNNTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAANTATATANGGAAACNNCAACCANTTCGTCTCAATCTTTAATACCGTTACCGATGTCNAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCNAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGNAGGTCACCGTANNTCAAATTTATCTATTTTATTNAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTNTTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGNAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATNNNNNCATTCGGATTNCGAGANTNCGTTNCNGATAGACNNNNATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATNAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTNAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGNTTTNCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGNAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGNAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGNTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGANNNNTANATTTNCAATATGTATNNNNNNNNNNNNNNNNNNNNNNNNGATTGCANGAAATNTTGANNNNCAANCGGCCNCTCNTATCGTTTNANAATAATACAGAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACGCATTANCCACGTTCACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCNNGTTCNNNANNTCATAGGTGGAGNCTTTATCNNNNNACAATCNNNNNNAAAAGTANNNATTAATCTANTAGAAAAGATTACAACATGGCCAAAATTTANGGTTGTTNANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTCATTNGACGTAGTTTATCATACGNTATGCCTCNNNAAGTTGTCTATCTAGTAAANGCGATAATAGANANNGCTAANNNACTTANCGAATCTATTACTGACTTTNATATTGNNNNNTACATTAATGACCTGGTGNNAGCTGAACACNNNAAACNAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACNTTTTACCTCNNATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACNTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATNCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGNGTGGAAAGTTCNNAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTNCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGNAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCNAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATNNGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCNAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTNAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTNNAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGNNNACGTGGAGGAGGTATCAAGTTTGNAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCNNCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCNTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCNTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCNNATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCNTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCNATGCTTCCNNGNNATAGTCTGGAACACTAATGGGTGACGNAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGNGCGGCNGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATNNCATATCATATTNNAAAATCTTGATNGAAGNNCGAATATCTCGTCTGACNNAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTNCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGNTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGNTTTTCTACCTCAGTGGCGAAATCTTTGGNGTGTTTGGTACANTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGNTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCNTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCNAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCNTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAANAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTNAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATNAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCNAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATNGGAAATGTAATAGTAANTTTTTATCATAAAAGTTGTAAAGTAAATAANAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCNGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTNNAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTNTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGANTATTATACTCTGTATTAGTTCNGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGNAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATANNCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATNAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAANTTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCNTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTNAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCNTAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGNAGTTANTTACGTTGAACAAGTNCATGGNAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTNGAGGATGTGATTCCATAGGCAGTCNNNAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACANTTTCTTNNNATTAACGAGAATGGCGTTTNATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGANGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACNGAAATACTATATCNNNCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGANACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATNAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAANNTTTTTTATAGTATGAAGGNNNNGATGNNNNNNNNNATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATNAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTANTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTNAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATNAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTNGATAATCCATTTATNTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTANNNGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTNNNNNNAAATACNTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATANGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTNAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATANCCAATAGAATAGTATTCTCAGAGTTGACGAATANTNGTNNNGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTNNGACGATGAATNCGGTAAATGGNNGACGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCGATTTTGTAGTAGATGATNCGNAACAATCTCAGATATGGGAAATTTCAGGAGCAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNANGAAATAAATCATATNNAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTNAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCNTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCNAGACTACATTNNNGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATANNTTTTTTTAAGCACGAAATNAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTANGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCNNAAAGNAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGNGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTANTTTTTTCTGTAATAGTTANAAANNACNNNCGATGGTCTATCTACCAGATTATNNNNTGTTATAAGGTACTTTNNTCNTAATAAACTAGAGTATGAGTAAGATAGTGNTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTNAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATNAAAATGTNCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATANNTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGNAACATACGATAAAGNAAAAGATTGTTGGACATTNGATAATGGTCACTTGTTACCACATAATTATATAATGNNTAAATGCGAACCGTTTNAACATAGATATCCATTNNNNAAAANACAGTACACGAATGATTTTCNNNAGTATTTNNNAAGNTTTATANNNAGTTNATAGAACAAAATACATNANTTTGTNAAAATAAATCACNTTTTATACTAATATGNNACAATTANCAATACTTTTGTTACTANNNNCNNTAGTATACGCTACACCTNNTCCTCNGANATCTNAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATNAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTNNANNCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCNAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTNNNTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTNTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACNATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGNTTTATACAAATCCATTAATGTNGAATATCGATTCTTNGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAANAATAATAGACTACCAGNAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGNAATATAGTCTTGGATCAAATAGATAAGAATAAANTATATCTAGTGGATTACGGATTGGTTTCTAAANTCATGTCTAACGGCGAACATGNTCCNNNNATAAGAAANCCAAATNAAATNGATNNNNGTACTCNAGAATTTACACCTATAGATTCGCATNAANNATACNNNNNNNNNAGACGTGGTGATCTAGAAACANNNNGATATTGTANGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAATTGCNNNAATATATTANNATGGTANNNNNNNNNACATATTTTGAGGAACCNAATTACGACNANNTTNNNNNNNTNTTNNNNNNNNGANNTNNNNNAAATTTTTNTNGATNNAANNNNNNNAAAAATAACTNNGTTATTATCANNCTCGTGAGNANAATNGAAACANNNNGNNGNNNNACGNNCACGCTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCATCGACNGTTGCCNNNNNNGTCANGAAATATTCTGTTGTGTCAGTTTATAATNAAAAGTATAACATTGTAAAAAACAAANATATGTGGTGTAACAGTCAAGNGAACAAGAGATATATTNGAGNNNNNNNNNNNNNGTNTGAATGCAATGAATATCTACAAATTGGAGATNCAATCCATGATCTAGAAGGAAATCAAATNTNTATTGTCACATATCGCCACAAAAACNACNATGNTCNAAGTGGAANNNNNNACGAGAGTCTAGANNTGTGNTTGGAANGAGTANGGATNNNTCATCACGTACTTGAAACAGGAANNNNGGTATATGGAAAAGTNCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGNGNCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCNNTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGNGAAAGACACTGAATCAATNGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATNGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGANTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACNTTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATNNAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGNTTTTTGTATCAAAGACATTAATACTTTAATGAGATACNGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATNCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAATACTTNNNNGAATGATANNNTCNCGTGTCCTANNNNNNNNNNNNNNNNNNNNCNNTTAGAACACNGATCNTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCCAACANNTGTACGATCTAACGAAGAATTTGATCCAGTNGATGATGGTNCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATNAGCTAGAATCAATTAGATGTCTTCTTCAGTNGATGTTGATATCTACGATGCCGTTAGAGCANTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTNGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACANTTAATGGTATAATGATGAATGAATTCGATACNGTATGNGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTNTAGCTAATNNGAGATATNGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATNAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGNTGCATCCTATTCGAATAATGAGTACANNCCGTTTAATAAACTGAGTGTNAAACTCNATATNGANNGAGTAGATAATATAGNAAATNNNNATACTGATGATAATAATNAANNNGTGTTANNNNNTNAANAGTNNACNNTTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCANAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCNAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACNTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCNATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGANNNAACATNGGGNTTAAAAATANGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACNGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACNCAACAAACACGTCTTGGATCATCNCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCNAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCNGGAGACATAAAATTTGAGGAGNATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTTAACAATTNGTTCTGATCTACAGACANNNNTTAATAAATCANCTTATTTTNCCAANATATTAAAANNNNNNNACNNCACNNNTNNNNNNNNATTGTGCGNCTTTCAAGATGATGNNNNATATAGGGTNNTACAGTTTTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAAATTATTTGNNTAGAATATTACGNNTATAATTGTTTNGAAATTTATAGAATAACNNNTATTAATACATTATNGTATATCTACAACGNTATNAGNNNCTTCATATTNGATAATATTACTANTAATATNNNNGGATNCAGANTTNNNNNNNTTGCCTAAATACATNNTTATAGNNTTACNNNGACAATCACCTAAATGTTTTNNACGNAGATAANNNGGTAAAGATTATNNNNACTTNTANNNCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATANNTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATNGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATANAGATGTAGAAGATATCATGAATGAAATAGATAGAGANAAAGAAGAAATACTNAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTANAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCNCGATGTAGGAATATAGANCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGNTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATNGATCATAAATCACNCAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCNTTGACTATCAACAACTGGACACGAGAANNTGGTATAAANNATTTGGCTATTNCAGATCTGNNTNNAATTGGAGAAACCGATGATTATATGTTCNTCATTATAANNAATTTGGGAAGAGNANTCGCCCCAAAGGATNGTGAATCAGNNTTCGAAGCATGTGTCACTATGATNAACACGTTNGAGTTTATACACTCTCAAGGATTTACTCATGGNAAAATNGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGANGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTNCATGGNNAAACGAAAGTAGTATNNAAGTAATAAAACNNAAAAAAGAATATAAACAATTTATAGCTACNTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAANTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATNNTANNCNNNTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCNAATATTAATATTAGACTATCTCTANCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCANCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATNNCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNNNCTTTAAAGCNNAATNGTTGATGCCATTCGAAANNGAATTTACCAGTGATTATCCCNNNNACGTATCTCCNNNNNAAATNGTAGNNGNNNGNATNATGTCTATTTNCGGCGAGCCANTTAATCACGCATCTNNNNNNNAATCATTCNGNAACNNNNCAATCATAGAACTGCCATATGTTGGNGATNCTAGTATGATGGNCATTCTTCCNAACAAGATTGATGGATTAGAATCCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATAATCTTGTNNATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGNGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGANGNGTATACAGAAGCAGCTGCAGCAACTTCNGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCNTTTCGTTGGTAGATATTGCTNTNCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACANNTTTTTTTAAAAATAGNAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTNGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTNGATNTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGNNNNNNNNANNNNNNNNNNNNNNNNTTTAAAGATGATGNGGAATCAGTNNNNATCGACGTNCGTGAGCTGGNNAAAAATATGCCGTGGGATAATGTTNAGGATTGTACAGAGATCATCCGTTGTTATANANNGGATGAGCNAAAANNNATCNNNNAGATTTCGGCCATCATTGGANTTTNTNNATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACNTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATANTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGANNATATATATATATATATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACNTCAATAGGTNGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTNGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACNNTATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGANCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGNTCTCNGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATNGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTNTACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTNAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATNAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTTTAGATANCNNTAGATCACTTGATGGGTANGATATTAATTGTTACTTNNNNNGACGTACACCACTTCATTGCGCTATACAATATNNNNNNACNCAGATTGCTGANTACTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTGATTAGTCGTCTACCGCCTAAAAGNGTNATATGCTCACTGACTAACCATATAATAGATTATGTTCNTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTANNAAGTACGTACTGTTACTGGACCCATCNNNNTATTATAGANTCAGNAATGTTATCGNNNACAAATTAGACCAATACAATAATCGTTATAATATNTTCGAACACGATANNGACGTTAANNNNNNNTATGGCAAAGTCNTACATGANCTNGATACATATATCNAGGNNGTNNAAGTATTAAAATCTACTTCCATCNNNAATAATATAACACTATACGACACNNNTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAANCTNATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTANAGAAATATACTTTAACTNATATAGTCCTNNAGNATATGATCTCATCTCNNTCTCAATCATCTTATTTGAGTCGTATTNCTAATGAGANNNTACTCGAAATATTATATAAANTCGACATGTACGATTTANNNNNNNNNNNNNNNNNNNATATNNGAGAGAATGATATCACAGAGTATCATATNNAGAATACGANGTCTGTTTCTNNANNGACATGAATAATGANNACACATNNAACNNNNTTTTTAATCTTNGATATAACACTAATTACATCNAGATTATATATTNAAATCGTAATTTGAGTTGTCTGATCNNCATGNNNNNNNNAAANNATATACNNAACATNNGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATATAGAGAATATGAATGAGAATACANCCGATGATNAGNAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACNAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGNAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTANAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTNAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCNAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCNAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATNGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGNAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGNTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATNCATAAAAATGACACTGTTGACAATAACACNATGGTTGATNANGNGACANCTAACAATAACACATTACATGGTAATATAGGANTTTTNGAAANAAATAATTGTTATANNNTTTCNGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACANGAACNAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTNATGGCATCCGTTATTCCTGCAGTTAANGAANTTAACAATACGTTGATGAAAATTGGTGTNAAAGATNATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTNTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTANNNACAATAGTGTTTCGACNNCTAACAGCAGNAAAAGACGAGATCTGAATGATGAGTTTGAATTTTNCACTTNCNAGGAATTAGATTGTCTTTACGAATCNTATGGTGTAAANNATGATATAAGTCATTGTTTTGCATCACCTAGACNNNGACGATCNGACGACNAAANNNNGTACATGGACNNGNAATTATTCNACNNCGNNNANNNNNANTTNGGAATAGACAGTGTTATTNCTNGANGTACAACCCATTTNCAAGTANGTGCATCTGGTGCNNNTGGTGGTGTTGNAGGAGATAGNTTNNCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGNAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCNAAAGCTTTCTAATGTTNGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCNAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTNCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTNAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATNAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTNAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCNGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATNTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTNACAAAATCCATTTAGACAAGAAGGGACATATAAGCNACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAANCTATGATATTGGAAGATGTATNATNGTGTAGTTCTAGAACTAGNAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTNTTACAGCAACCTCCTTNNACATTCGAATTCATTCNTGACAATTCTAACGAATATGTGGATANAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGNCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACNAAGATATAAAAGACATTATAGAATCCGAAGAANGTAAGAGATNNNNTATAATAGATGTTANNAACAATCTTGTTNNAAAGTACTATTNTATTGATAATTATCNNTGTNATACTTTAGATGATTATATATACANCTCTGNAGAATATAACAANNNCTNTNTGTTAGNAAACGATACTTNTATANGCNNNNACTATCNTGAATCATCAGNNGTANNNGTTNTATCATNTTATGAAANGACTANAATCTCCTTNGATACNAAAGACGCCAAAGATGCTATAGAAGATGTGANNNTAGCNAGTGCNGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATNAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGANNTTTTTTAAATGAGTATCGGTAGTTACANNNTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTANCNNGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGNTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGNNCACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGNGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAANGGTACTTATNCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTNATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCNNGATTTTCGCATTGACTTTACACAGACATGAACATNCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAANGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTNCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCNAAAACTCACTTTTGANTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATNAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATNNAANTGATATAACNAATACAGCAGATATATTGCTNGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGNAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATNAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGNNAGTTAAGTNNTNNGTTAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGNNNNAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATNAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGNACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTNGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATNTTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTNCATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCNGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAANNAAAGTGTGGAATAGGATACGGAGTATCCGGNTACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTNCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTANNAACTTCAGGATTCTTTACNGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTNGNNNNNNNNNNNNNNAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTNTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATNCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGNNAGNTNCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGANNTATCCGAAGAAGTTGTNAAAGGAGATCCCACCACTTATTACACTATCGTCNGTGCGGGTCTTNNNATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACANTGTGAATACTAGATTGTCCAGCGTGTCACCNGGACAAGGTAAGGANNCTNCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATNCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGNTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGNNCGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCNNCGGATCGGCATCTGAAGGTGCAACCGATGATACTTNACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGNAAATGGATGAGTTNGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACNAAAATATTTAACTACATTCACAAAAAGTTANNNCTCGTTACTTCTTCNTTCTGTTTCAATATGTGATACGATATGATCACTATTCNTNTTCTCTTGGTCTCATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +>Monkeypox/PT0008/2022|sampling_date_20220515 +TAATTAATTTAATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTTGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTANTAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTTGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGAGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTNNANNNNNNNNNNNNNNNNNNGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGAGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTAAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAAAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATTAAATTAATTA +>ON676708 +ATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATTATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGTTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTTTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGNNNNATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATNNNAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAAT +>ON843165 +TAATTAATTTAATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTTTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTTGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGAGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGAGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGNNNNNNNNGCNNNNNNNNNNNNNTTTCACGACGACCTCGATCNNNNNNNNNTNNCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATTAAATTAATTA diff --git a/data_output/nextstrain/mpox/clade-iib/unreleased/tree.json b/data_output/nextstrain/mpox/clade-iib/unreleased/tree.json new file mode 100644 index 00000000..8417705e --- /dev/null +++ b/data_output/nextstrain/mpox/clade-iib/unreleased/tree.json @@ -0,0 +1 @@ +{"version":"v2","meta":{"title":"Nextclade reference tree for Mpox virus (Clade IIb)","updated":"2023-11-21","build_url":"https://github.com/nextstrain/mpox/nextclade","data_provenance":[{"name":"GenBank","url":"https://www.ncbi.nlm.nih.gov/genbank/"}],"maintainers":[{"name":"Cornelius Roemer","url":"https://neherlab.org"},{"name":"Richard Neher","url":"https://neherlab.org"},{"name":"Nextstrain team","url":"https://nextstrain.org"}],"display_defaults":{"color_by":"lineage","map_triplicate":false,"distance_measure":"div","tip_label":"strain_display","transmission_lines":false},"genome_annotations":{"OPG001":{"end":1575,"seqid":"resources/genome_annotation.gff3","start":835,"strand":"-","type":"gene"},"OPG001_dup":{"end":196375,"seqid":"resources/genome_annotation.gff3","start":195635,"strand":"+","type":"gene"},"OPG002":{"end":2751,"seqid":"resources/genome_annotation.gff3","start":1702,"strand":"-","type":"gene"},"OPG002_dup":{"end":195508,"seqid":"resources/genome_annotation.gff3","start":194459,"strand":"+","type":"gene"},"OPG003":{"end":4607,"seqid":"resources/genome_annotation.gff3","start":2841,"strand":"-","type":"gene"},"OPG003_dup":{"end":194369,"seqid":"resources/genome_annotation.gff3","start":192603,"strand":"+","type":"gene"},"OPG005":{"end":189660,"seqid":"resources/genome_annotation.gff3","start":189199,"strand":"+","type":"gene"},"OPG015":{"end":6156,"seqid":"resources/genome_annotation.gff3","start":4843,"strand":"-","type":"gene"},"OPG015_dup":{"end":192367,"seqid":"resources/genome_annotation.gff3","start":191054,"strand":"+","type":"gene"},"OPG016":{"end":190940,"seqid":"resources/genome_annotation.gff3","start":190410,"strand":"+","type":"gene"},"OPG019":{"end":8008,"seqid":"resources/genome_annotation.gff3","start":7580,"strand":"+","type":"gene"},"OPG021":{"end":10315,"seqid":"resources/genome_annotation.gff3","start":9587,"strand":"+","type":"gene"},"OPG022":{"end":10858,"seqid":"resources/genome_annotation.gff3","start":10478,"strand":"-","type":"gene"},"OPG023":{"end":12900,"seqid":"resources/genome_annotation.gff3","start":10918,"strand":"-","type":"gene"},"OPG024":{"end":13228,"seqid":"resources/genome_annotation.gff3","start":13034,"strand":"-","type":"gene"},"OPG025":{"end":15267,"seqid":"resources/genome_annotation.gff3","start":13375,"strand":"-","type":"gene"},"OPG027":{"end":16377,"seqid":"resources/genome_annotation.gff3","start":15925,"strand":"-","type":"gene"},"OPG029":{"end":17069,"seqid":"resources/genome_annotation.gff3","start":16602,"strand":"-","type":"gene"},"OPG030":{"end":17833,"seqid":"resources/genome_annotation.gff3","start":17213,"strand":"-","type":"gene"},"OPG031":{"end":18828,"seqid":"resources/genome_annotation.gff3","start":17878,"strand":"-","type":"gene"},"OPG034":{"end":20005,"seqid":"resources/genome_annotation.gff3","start":19361,"strand":"-","type":"gene"},"OPG035":{"end":20404,"seqid":"resources/genome_annotation.gff3","start":20051,"strand":"-","type":"gene"},"OPG036":{"end":21064,"seqid":"resources/genome_annotation.gff3","start":20531,"strand":"-","type":"gene"},"OPG037":{"end":22433,"seqid":"resources/genome_annotation.gff3","start":21105,"strand":"-","type":"gene"},"OPG038":{"end":23159,"seqid":"resources/genome_annotation.gff3","start":22497,"strand":"-","type":"gene"},"OPG039":{"end":24118,"seqid":"resources/genome_annotation.gff3","start":23264,"strand":"-","type":"gene"},"OPG040":{"end":25478,"seqid":"resources/genome_annotation.gff3","start":24351,"strand":"-","type":"gene"},"OPG042":{"end":27097,"seqid":"resources/genome_annotation.gff3","start":25823,"strand":"-","type":"gene"},"OPG043":{"end":27955,"seqid":"resources/genome_annotation.gff3","start":27125,"strand":"-","type":"gene"},"OPG044":{"end":28540,"seqid":"resources/genome_annotation.gff3","start":28091,"strand":"+","type":"gene"},"OPG045":{"end":29262,"seqid":"resources/genome_annotation.gff3","start":28603,"strand":"-","type":"gene"},"OPG046":{"end":29729,"seqid":"resources/genome_annotation.gff3","start":29274,"strand":"-","type":"gene"},"OPG047":{"end":31194,"seqid":"resources/genome_annotation.gff3","start":29746,"strand":"-","type":"gene"},"OPG048":{"end":32164,"seqid":"resources/genome_annotation.gff3","start":31205,"strand":"-","type":"gene"},"OPG049":{"end":33151,"seqid":"resources/genome_annotation.gff3","start":32195,"strand":"-","type":"gene"},"OPG050":{"end":33408,"seqid":"resources/genome_annotation.gff3","start":33181,"strand":"-","type":"gene"},"OPG051":{"end":33649,"seqid":"resources/genome_annotation.gff3","start":33425,"strand":"-","type":"gene"},"OPG052":{"end":33995,"seqid":"resources/genome_annotation.gff3","start":33801,"strand":"-","type":"gene"},"OPG053":{"end":34690,"seqid":"resources/genome_annotation.gff3","start":34052,"strand":"-","type":"gene"},"OPG054":{"end":35996,"seqid":"resources/genome_annotation.gff3","start":34677,"strand":"-","type":"gene"},"OPG055":{"end":37083,"seqid":"resources/genome_annotation.gff3","start":36019,"strand":"-","type":"gene"},"OPG056":{"end":39034,"seqid":"resources/genome_annotation.gff3","start":37127,"strand":"-","type":"gene"},"OPG057":{"end":40195,"seqid":"resources/genome_annotation.gff3","start":39077,"strand":"-","type":"gene"},"OPG058":{"end":40434,"seqid":"resources/genome_annotation.gff3","start":40213,"strand":"-","type":"gene"},"OPG059":{"end":40633,"seqid":"resources/genome_annotation.gff3","start":40484,"strand":"-","type":"gene"},"OPG060":{"end":41182,"seqid":"resources/genome_annotation.gff3","start":40706,"strand":"-","type":"gene"},"OPG061":{"end":41884,"seqid":"resources/genome_annotation.gff3","start":41189,"strand":"-","type":"gene"},"OPG062":{"end":42252,"seqid":"resources/genome_annotation.gff3","start":41947,"strand":"+","type":"gene"},"OPG063":{"end":43688,"seqid":"resources/genome_annotation.gff3","start":42249,"strand":"-","type":"gene"},"OPG064":{"end":45898,"seqid":"resources/genome_annotation.gff3","start":43685,"strand":"-","type":"gene"},"OPG065":{"end":46483,"seqid":"resources/genome_annotation.gff3","start":46022,"strand":"-","type":"gene"},"OPG066":{"end":47428,"seqid":"resources/genome_annotation.gff3","start":46649,"strand":"-","type":"gene"},"OPG068":{"end":49904,"seqid":"resources/genome_annotation.gff3","start":48201,"strand":"+","type":"gene"},"OPG069":{"end":50486,"seqid":"resources/genome_annotation.gff3","start":49986,"strand":"+","type":"gene"},"OPG070":{"end":51411,"seqid":"resources/genome_annotation.gff3","start":50590,"strand":"+","type":"gene"},"OPG071":{"end":54438,"seqid":"resources/genome_annotation.gff3","start":51418,"strand":"-","type":"gene"},"OPG072":{"end":54757,"seqid":"resources/genome_annotation.gff3","start":54470,"strand":"+","type":"gene"},"OPG073":{"end":55141,"seqid":"resources/genome_annotation.gff3","start":54752,"strand":"-","type":"gene"},"OPG074":{"end":57125,"seqid":"resources/genome_annotation.gff3","start":55128,"strand":"-","type":"gene"},"OPG075":{"end":57498,"seqid":"resources/genome_annotation.gff3","start":57172,"strand":"-","type":"gene"},"OPG076":{"end":57630,"seqid":"resources/genome_annotation.gff3","start":57523,"strand":"-","type":"gene"},"OPG077":{"end":58583,"seqid":"resources/genome_annotation.gff3","start":57645,"strand":"-","type":"gene"},"OPG078":{"end":58811,"seqid":"resources/genome_annotation.gff3","start":58590,"strand":"-","type":"gene"},"OPG079":{"end":59621,"seqid":"resources/genome_annotation.gff3","start":58812,"strand":"-","type":"gene"},"OPG080":{"end":62018,"seqid":"resources/genome_annotation.gff3","start":59703,"strand":"-","type":"gene"},"OPG081":{"end":62285,"seqid":"resources/genome_annotation.gff3","start":62046,"strand":"-","type":"gene"},"OPG082":{"end":63452,"seqid":"resources/genome_annotation.gff3","start":62304,"strand":"-","type":"gene"},"OPG083":{"end":64716,"seqid":"resources/genome_annotation.gff3","start":63445,"strand":"-","type":"gene"},"OPG084":{"end":66752,"seqid":"resources/genome_annotation.gff3","start":64722,"strand":"+","type":"gene"},"OPG085":{"end":68531,"seqid":"resources/genome_annotation.gff3","start":66756,"strand":"-","type":"gene"},"OPG086":{"end":68863,"seqid":"resources/genome_annotation.gff3","start":68528,"strand":"-","type":"gene"},"OPG087":{"end":69519,"seqid":"resources/genome_annotation.gff3","start":68857,"strand":"+","type":"gene"},"OPG088":{"end":69863,"seqid":"resources/genome_annotation.gff3","start":69489,"strand":"-","type":"gene"},"OPG089":{"end":71170,"seqid":"resources/genome_annotation.gff3","start":69866,"strand":"+","type":"gene"},"OPG090":{"end":71370,"seqid":"resources/genome_annotation.gff3","start":71179,"strand":"+","type":"gene"},"OPG091":{"end":71867,"seqid":"resources/genome_annotation.gff3","start":71370,"strand":"+","type":"gene"},"OPG092":{"end":72947,"seqid":"resources/genome_annotation.gff3","start":71832,"strand":"-","type":"gene"},"OPG093":{"end":73760,"seqid":"resources/genome_annotation.gff3","start":72978,"strand":"+","type":"gene"},"OPG094":{"end":74802,"seqid":"resources/genome_annotation.gff3","start":73780,"strand":"+","type":"gene"},"OPG095":{"end":75555,"seqid":"resources/genome_annotation.gff3","start":74803,"strand":"+","type":"gene"},"OPG096":{"end":75865,"seqid":"resources/genome_annotation.gff3","start":75587,"strand":"+","type":"gene"},"OPG097":{"end":76875,"seqid":"resources/genome_annotation.gff3","start":75841,"strand":"-","type":"gene"},"OPG098":{"end":77655,"seqid":"resources/genome_annotation.gff3","start":76900,"strand":"+","type":"gene"},"OPG099":{"end":78051,"seqid":"resources/genome_annotation.gff3","start":77665,"strand":"+","type":"gene"},"OPG100":{"end":78466,"seqid":"resources/genome_annotation.gff3","start":78008,"strand":"+","type":"gene"},"OPG101":{"end":79019,"seqid":"resources/genome_annotation.gff3","start":78486,"strand":"+","type":"gene"},"OPG102":{"end":80086,"seqid":"resources/genome_annotation.gff3","start":79085,"strand":"+","type":"gene"},"OPG103":{"end":80558,"seqid":"resources/genome_annotation.gff3","start":80001,"strand":"+","type":"gene"},"OPG104":{"end":81019,"seqid":"resources/genome_annotation.gff3","start":80618,"strand":"-","type":"gene"},"OPG105":{"end":84986,"seqid":"resources/genome_annotation.gff3","start":81126,"strand":"+","type":"gene"},"OPG106":{"end":85498,"seqid":"resources/genome_annotation.gff3","start":84983,"strand":"-","type":"gene"},"OPG107":{"end":86081,"seqid":"resources/genome_annotation.gff3","start":85512,"strand":"+","type":"gene"},"OPG108":{"end":87059,"seqid":"resources/genome_annotation.gff3","start":86085,"strand":"-","type":"gene"},"OPG109":{"end":89447,"seqid":"resources/genome_annotation.gff3","start":87060,"strand":"-","type":"gene"},"OPG110":{"end":90264,"seqid":"resources/genome_annotation.gff3","start":89632,"strand":"+","type":"gene"},"OPG111":{"end":91209,"seqid":"resources/genome_annotation.gff3","start":90265,"strand":"+","type":"gene"},"OPG112":{"end":91687,"seqid":"resources/genome_annotation.gff3","start":91247,"strand":"+","type":"gene"},"OPG113":{"end":94268,"seqid":"resources/genome_annotation.gff3","start":91731,"strand":"+","type":"gene"},"OPG114":{"end":94667,"seqid":"resources/genome_annotation.gff3","start":94227,"strand":"-","type":"gene"},"OPG115":{"end":95361,"seqid":"resources/genome_annotation.gff3","start":94660,"strand":"+","type":"gene"},"OPG116":{"end":96017,"seqid":"resources/genome_annotation.gff3","start":95361,"strand":"+","type":"gene"},"OPG117":{"end":98406,"seqid":"resources/genome_annotation.gff3","start":96049,"strand":"+","type":"gene"},"OPG118":{"end":100359,"seqid":"resources/genome_annotation.gff3","start":98446,"strand":"+","type":"gene"},"OPG119":{"end":100871,"seqid":"resources/genome_annotation.gff3","start":100386,"strand":"+","type":"gene"},"OPG120":{"end":101748,"seqid":"resources/genome_annotation.gff3","start":100834,"strand":"-","type":"gene"},"OPG121":{"end":102431,"seqid":"resources/genome_annotation.gff3","start":101790,"strand":"+","type":"gene"},"OPG122":{"end":103174,"seqid":"resources/genome_annotation.gff3","start":102428,"strand":"+","type":"gene"},"OPG123":{"end":105070,"seqid":"resources/genome_annotation.gff3","start":103175,"strand":"-","type":"gene"},"OPG124":{"end":105968,"seqid":"resources/genome_annotation.gff3","start":105105,"strand":"-","type":"gene"},"OPG125":{"end":107654,"seqid":"resources/genome_annotation.gff3","start":105999,"strand":"-","type":"gene"},"OPG126":{"end":108130,"seqid":"resources/genome_annotation.gff3","start":107678,"strand":"-","type":"gene"},"OPG127":{"end":108825,"seqid":"resources/genome_annotation.gff3","start":108151,"strand":"-","type":"gene"},"OPG128":{"end":109055,"seqid":"resources/genome_annotation.gff3","start":108822,"strand":"-","type":"gene"},"OPG129":{"end":111004,"seqid":"resources/genome_annotation.gff3","start":109070,"strand":"-","type":"gene"},"OPG130":{"end":111902,"seqid":"resources/genome_annotation.gff3","start":111057,"strand":"-","type":"gene"},"OPG131":{"end":112425,"seqid":"resources/genome_annotation.gff3","start":111940,"strand":"+","type":"gene"},"OPG132":{"end":113540,"seqid":"resources/genome_annotation.gff3","start":112422,"strand":"-","type":"gene"},"OPG133":{"end":115696,"seqid":"resources/genome_annotation.gff3","start":113564,"strand":"-","type":"gene"},"OPG134":{"end":116628,"seqid":"resources/genome_annotation.gff3","start":115750,"strand":"+","type":"gene"},"OPG135":{"end":116911,"seqid":"resources/genome_annotation.gff3","start":116609,"strand":"-","type":"gene"},"OPG136":{"end":119587,"seqid":"resources/genome_annotation.gff3","start":116912,"strand":"-","type":"gene"},"OPG137":{"end":120558,"seqid":"resources/genome_annotation.gff3","start":119602,"strand":"+","type":"gene"},"OPG138":{"end":121132,"seqid":"resources/genome_annotation.gff3","start":120560,"strand":"-","type":"gene"},"OPG139":{"end":121368,"seqid":"resources/genome_annotation.gff3","start":121156,"strand":"-","type":"gene"},"OPG140":{"end":121746,"seqid":"resources/genome_annotation.gff3","start":121474,"strand":"-","type":"gene"},"OPG141":{"end":121924,"seqid":"resources/genome_annotation.gff3","start":121763,"strand":"-","type":"gene"},"OPG142":{"end":122198,"seqid":"resources/genome_annotation.gff3","start":121914,"strand":"-","type":"gene"},"OPG143":{"end":123315,"seqid":"resources/genome_annotation.gff3","start":122182,"strand":"-","type":"gene"},"OPG144":{"end":123932,"seqid":"resources/genome_annotation.gff3","start":123318,"strand":"-","type":"gene"},"OPG145":{"end":125425,"seqid":"resources/genome_annotation.gff3","start":123947,"strand":"+","type":"gene"},"OPG146":{"end":125639,"seqid":"resources/genome_annotation.gff3","start":125406,"strand":"-","type":"gene"},"OPG147":{"end":125987,"seqid":"resources/genome_annotation.gff3","start":125640,"strand":"-","type":"gene"},"OPG148":{"end":127266,"seqid":"resources/genome_annotation.gff3","start":125986,"strand":"+","type":"gene"},"OPG149":{"end":127759,"seqid":"resources/genome_annotation.gff3","start":127196,"strand":"+","type":"gene"},"OPG150":{"end":128927,"seqid":"resources/genome_annotation.gff3","start":127779,"strand":"+","type":"gene"},"OPG151":{"end":132418,"seqid":"resources/genome_annotation.gff3","start":128924,"strand":"+","type":"gene"},"OPG153":{"end":137667,"seqid":"resources/genome_annotation.gff3","start":136138,"strand":"-","type":"gene"},"OPG154":{"end":138050,"seqid":"resources/genome_annotation.gff3","start":137718,"strand":"-","type":"gene"},"OPG155":{"end":138491,"seqid":"resources/genome_annotation.gff3","start":138051,"strand":"-","type":"gene"},"OPG156":{"end":139409,"seqid":"resources/genome_annotation.gff3","start":138492,"strand":"-","type":"gene"},"OPG157":{"end":139608,"seqid":"resources/genome_annotation.gff3","start":139372,"strand":"-","type":"gene"},"OPG158":{"end":139769,"seqid":"resources/genome_annotation.gff3","start":139641,"strand":"-","type":"gene"},"OPG159":{"end":140205,"seqid":"resources/genome_annotation.gff3","start":139768,"strand":"+","type":"gene"},"OPG160":{"end":141074,"seqid":"resources/genome_annotation.gff3","start":140172,"strand":"-","type":"gene"},"OPG161":{"end":141647,"seqid":"resources/genome_annotation.gff3","start":141102,"strand":"+","type":"gene"},"OPG162":{"end":142158,"seqid":"resources/genome_annotation.gff3","start":141652,"strand":"+","type":"gene"},"OPG163":{"end":142732,"seqid":"resources/genome_annotation.gff3","start":142202,"strand":"+","type":"gene"},"OPG164":{"end":143464,"seqid":"resources/genome_annotation.gff3","start":142778,"strand":"+","type":"gene"},"OPG165":{"end":144322,"seqid":"resources/genome_annotation.gff3","start":143516,"strand":"+","type":"gene"},"OPG166":{"end":144577,"seqid":"resources/genome_annotation.gff3","start":144398,"strand":"+","type":"gene"},"OPG167":{"end":145407,"seqid":"resources/genome_annotation.gff3","start":144574,"strand":"-","type":"gene"},"OPG170":{"end":146778,"seqid":"resources/genome_annotation.gff3","start":146113,"strand":"-","type":"gene"},"OPG171":{"end":147389,"seqid":"resources/genome_annotation.gff3","start":146988,"strand":"+","type":"gene"},"OPG172":{"end":148017,"seqid":"resources/genome_annotation.gff3","start":147427,"strand":"+","type":"gene"},"OPG173":{"end":148261,"seqid":"resources/genome_annotation.gff3","start":148037,"strand":"+","type":"gene"},"OPG174":{"end":149395,"seqid":"resources/genome_annotation.gff3","start":148355,"strand":"-","type":"gene"},"OPG175":{"end":149819,"seqid":"resources/genome_annotation.gff3","start":149442,"strand":"+","type":"gene"},"OPG176":{"end":150531,"seqid":"resources/genome_annotation.gff3","start":149809,"strand":"+","type":"gene"},"OPG178":{"end":152123,"seqid":"resources/genome_annotation.gff3","start":151509,"strand":"+","type":"gene"},"OPG180":{"end":154371,"seqid":"resources/genome_annotation.gff3","start":152692,"strand":"+","type":"gene"},"OPG181":{"end":155416,"seqid":"resources/genome_annotation.gff3","start":154412,"strand":"+","type":"gene"},"OPG185":{"end":159858,"seqid":"resources/genome_annotation.gff3","start":158917,"strand":"+","type":"gene"},"OPG187":{"end":161533,"seqid":"resources/genome_annotation.gff3","start":160622,"strand":"+","type":"gene"},"OPG188":{"end":163107,"seqid":"resources/genome_annotation.gff3","start":161596,"strand":"+","type":"gene"},"OPG189":{"end":165018,"seqid":"resources/genome_annotation.gff3","start":163333,"strand":"+","type":"gene"},"OPG190":{"end":166075,"seqid":"resources/genome_annotation.gff3","start":165122,"strand":"+","type":"gene"},"OPG191":{"end":166667,"seqid":"resources/genome_annotation.gff3","start":166161,"strand":"+","type":"gene"},"OPG192":{"end":167279,"seqid":"resources/genome_annotation.gff3","start":166731,"strand":"+","type":"gene"},"OPG193":{"end":168137,"seqid":"resources/genome_annotation.gff3","start":167334,"strand":"+","type":"gene"},"OPG195":{"end":168895,"seqid":"resources/genome_annotation.gff3","start":168230,"strand":"+","type":"gene"},"OPG197":{"end":169972,"seqid":"resources/genome_annotation.gff3","start":169670,"strand":"+","type":"gene"},"OPG198":{"end":170886,"seqid":"resources/genome_annotation.gff3","start":170038,"strand":"+","type":"gene"},"OPG199":{"end":172022,"seqid":"resources/genome_annotation.gff3","start":170988,"strand":"+","type":"gene"},"OPG200":{"end":172599,"seqid":"resources/genome_annotation.gff3","start":172150,"strand":"+","type":"gene"},"OPG204":{"end":175587,"seqid":"resources/genome_annotation.gff3","start":174532,"strand":"+","type":"gene"},"OPG205":{"end":178019,"seqid":"resources/genome_annotation.gff3","start":175656,"strand":"+","type":"gene"},"OPG208":{"end":180339,"seqid":"resources/genome_annotation.gff3","start":179266,"strand":"+","type":"gene"},"OPG209":{"end":181090,"seqid":"resources/genome_annotation.gff3","start":180518,"strand":"+","type":"gene"},"OPG210":{"end":186998,"seqid":"resources/genome_annotation.gff3","start":181356,"strand":"+","type":"gene"},"nuc":{"end":197209,"start":1,"strand":"+","type":"source"}},"colorings":[{"key":"clade_membership","title":"Clade","type":"categorical","scale":[["IIb","#DEA73C"]]},{"key":"gt","title":"Genotype","type":"categorical"},{"key":"outbreak","title":"Outbreak","type":"categorical","scale":[["hMPXV-1","#4C90C0"]]},{"key":"lineage","title":"Lineage","type":"categorical","scale":[["A","#5E1D9D"],["A.1","#4D22AE"],["A.1.1","#4531BC"],["B.1","#4041C7"],["B.1.1","#3F53CD"],["B.1.2","#4064CF"],["B.1.3","#4375CD"],["C.1","#4784C8"],["B.1.4","#4C91BF"],["B.1.5","#539CB4"],["B.1.6","#5AA5A7"],["B.1.7","#63AC9A"],["B.1.8","#6CB28C"],["B.1.9","#77B67E"],["B.1.10","#82BA71"],["B.1.11","#8FBC66"],["B.1.12","#9CBE5B"],["B.1.13","#A9BD53"],["B.1.14","#B5BD4C"],["B.1.15","#C1BA46"],["B.1.16","#CDB642"],["B.1.17","#D6B03F"],["B.1.18","#DEA73B"],["B.1.19","#E39B39"],["B.1.20","#E68D36"],["A.2","#E67C33"],["A.2.1","#E5692F"],["A.2.2","#E1532B"],["A.2.3","#DE3E27"],["A.3","#DB2823"]]},{"key":"date","title":"Collection Date","type":"categorical"},{"key":"host","title":"Host","type":"categorical"},{"key":"strain","title":"Strain name","type":"categorical"},{"key":"strain_display","title":"Pretty strain name","type":"categorical"},{"key":"region","title":"Region","type":"categorical","scale":[["Asia","#447CCD"],["Oceania","#5EA9A1"],["Africa","#8ABB6A"],["Europe","#BEBB48"],["South America","#E29E39"],["North America","#E2562B"]]},{"key":"country","title":"Country","type":"categorical","scale":[["Israel","#5E1D9D"],["Singapore","#4E21AD"],["Vietnam","#462EB9"],["Taiwan","#403CC5"],["South Korea","#3F4CCB"],["Japan","#3E5DD0"],["Australia","#416CCE"],["Benin","#447BCD"],["Nigeria","#4887C6"],["South Africa","#4D93BE"],["Portugal","#539CB3"],["Ireland","#5AA5A8"],["Spain","#62AB9C"],["United Kingdom","#6AB18F"],["France","#74B582"],["Belgium","#7EB876"],["Netherlands","#89BB6B"],["Switzerland","#94BD61"],["Germany","#A0BE59"],["Italy","#ABBD51"],["Slovenia","#B7BD4B"],["Sweden","#C2BA46"],["Austria","#CCB742"],["Czech Republic","#D5B13F"],["Slovakia","#DDAA3C"],["Romania","#E19F3A"],["Finland","#E69537"],["Brazil","#E68534"],["Peru","#E67631"],["Colombia","#E4632E"],["Mexico","#E14F2A"],["USA","#DE3C26"],["Canada","#DB2823"]]}],"filters":["clade_membership","lineage","country","host","institution","region","strain_display","strain","date","outbreak"],"panels":["tree","entropy"],"extensions":{"nextclade":{"clade_node_attrs":[{"name":"outbreak","displayName":"Outbreak","description":""},{"name":"lineage","displayName":"Lineage","description":""}],"placement_mask_ranges":[{"begin":0,"end":1500},{"begin":133050,"end":133250},{"begin":136500,"end":136600},{"begin":140050,"end":140250},{"begin":146750,"end":147000},{"begin":150500,"end":150650},{"begin":169250,"end":169500},{"begin":169700,"end":169800},{"begin":173150,"end":173350},{"begin":179000,"end":179300},{"begin":190787,"end":197209}]}}},"tree":{"name":"NODE_0000001","node_attrs":{"div":0,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{},"labels":{"clade":"A"}},"children":[{"name":"NC_063383","node_attrs":{"div":0,"accession":"NC_063383","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Senkevich,T.G.,Yutin,N.,Wolf,Y.I.,Koonin,E.V.,Moss,B.,Zmasek,C.M.,Knipe,D.M.,Pellett,P.E.,Scheuermann,R.H.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Senkevich,T.G.,Yutin,N.,Wolf,Y.I.,Koonin,E.V.,Moss,B.,Zmasek,C.M.,Knipe,D.M.,Pellett,P.E.,Scheuermann,R.H."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Center for Biotechnology Information, NIH"},"lineage":{"value":"A"},"strain":{"value":"MPXV-M5312_HM12_Rivers"},"date":{"value":"2018-08-XX"},"strain_display":{"value":"Nigeria/NC_063383/2018-08-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000000","node_attrs":{"div":0,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{}},"children":[{"name":"NC_063383.1","node_attrs":{"div":0,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000002","node_attrs":{"div":5,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["T608-","T609-","A18769G","T28175C","A81977G","A100261G","T146895-","T146897-","T146898-","T146899-","T146900-","T146902-","T146903-","T146904-","T146905-","T146907-","T146909-","T146910-","T146911-","T146912-","T154408C","A196616-","A196617-"],"OPG118":["K606E"]},"labels":{"aa":"OPG118: K606E"}},"children":[{"name":"KJ642617","node_attrs":{"div":38,"accession":"KJ642617","author":{"author":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M.","value":"Nakazawa,Y.,Mauldin,M.R.,Emerson,G.L.,Reynolds,M.G.,Lash,R.R.,Gao,J.,Zhao,H.,Li,Y.,Muyembe,J.J.,Kingebeni,P.M.,Wemakoy,O.,Malekani,J.,Karem,K.L.,Damon,I.K.,Carroll,D.S.,Lil,Y.,Weil,R.M.,Muyembe,J.-J.,Kingbeni,P.M.,Balilo,M."},"country":{"value":"Nigeria"},"clade_membership":{"value":"outgroup"},"institution":{"value":"Poxvirus Program, Centres for Disease Control and prevention (US CDC), USA"},"strain":{"value":"KJ642617"},"date":{"value":"1971-XX-XX"},"strain_display":{"value":"Nigeria/KJ642617/1971-XX-XX"},"region":{"value":"Africa"}},"branch_attrs":{"mutations":{"nuc":["T607-","A3450G","A8893C","G13625A","A18312G","T19367C","A32210-","C32211-","G32212-","T33143C","A38067G","A46895G","G48138A","A48527C","A53207C","A66580G","T80986C","C92516T","G98489-","C98727T","T100562C","C105126T","T119718C","A128076G","A129762G","T133145C","T136555C","A137627G","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","A141300G","T141364C","A142450C","C146687T","A146894-","A146896-","A146901-","A146906-","A146908-","G149744A","G149878A","A158170-","G160174T","C160852T","A160867G","T166656-","T166657-","T167656G","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","A171675G","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","A178423G","A181253-","T187080-","T193760C","A196615-"],"OPG025":["T548M"],"OPG049":["R314-"],"OPG056":["V323A"],"OPG071":["L411W"],"OPG084":["Q620R"],"OPG104":["T12A"],"OPG150":["N100D"],"OPG151":["D280G"],"OPG153":["M14T"],"OPG159":["N124-","Y125-","N126-"],"OPG161":["K67E","V88A"],"OPG170":["G31D"],"OPG176":["D24N"],"OPG191":["F166-"],"OPG193":["I108R"],"OPG197":["T34-","D35-"],"OPG199":["K230E"]},"labels":{"aa":"OPG025: T548M; OPG049: R314-; OPG056: V323A; OPG071: L411W; OPG084: Q620R; OPG104: T12A; OPG150: N100D; OPG151: D280G; OPG153: M14T; OPG159: N124-, Y125-, N126-; OPG161: K67E, V88A; OPG170: G31D; OPG176: D24N; OPG191: F166-; OPG193: I108R; OPG197: T34-, D35-; OPG199: K230E","clade":"outgroup"}}},{"name":"OP535336","node_attrs":{"div":13,"accession":"OP535336","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2017_2946"},"date":{"value":"2017-10-XX"},"strain_display":{"value":"Nigeria/OP535336/2017-10-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C8634T","C33332T","C67253T","C110326T","C117099T","C122737T","G125303A","G129583A","A136552-","T136553-","C136554-","A146894-","A146896-","A146901-","A146906-","A146908-","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","T178048-"],"OPG050":["R26Q"],"OPG085":["D427N"],"OPG129":["E227K"],"OPG136":["R830Q"],"OPG145":["D453N"],"OPG153":["D385-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG050: R26Q; OPG085: D427N; OPG129: E227K; OPG136: R830Q; OPG145: D453N; OPG153: D385-; OPG197: T34-, D35-"}}},{"name":"NODE_0000003","node_attrs":{"div":8,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["C5157T","G7764A","G9782A","C133161T","A146894-","A146896-","A146901-","A146906-","A146908-","G192053A"],"OPG015":["D334N"],"OPG015_dup":["D334N"],"OPG019":["R62K"],"OPG021":["A66T"]},"labels":{"aa":"OPG015: D334N; OPG015_dup: D334N; OPG019: R62K; OPG021: A66T"}},"children":[{"name":"MK783031","node_attrs":{"div":9,"accession":"MK783031","author":{"author":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J.","value":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"NCEZID/DHCPP/PRB, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A"},"strain":{"value":"MK783031"},"date":{"value":"2017-11-09"},"strain_display":{"value":"Nigeria/MK783031/2017-11-09"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G109736A"]}}},{"name":"MK783027","node_attrs":{"div":8,"accession":"MK783027","author":{"author":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J.","value":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, NCEZID/DHCPP/PRB"},"lineage":{"value":"A"},"strain":{"value":"MK783027"},"date":{"value":"2017-11-09"},"strain_display":{"value":"Nigeria/MK783027/2017-11-09"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000004","node_attrs":{"div":8,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["G51559A","C60923T","G179884A"],"OPG080":["E366K"],"OPG208":["E207K"]},"labels":{"aa":"OPG080: E366K; OPG208: E207K"}},"children":[{"name":"MT903337","node_attrs":{"div":10,"accession":"MT903337","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A"},"strain":{"value":"MPXV-M2940_FCT"},"date":{"value":"2018-XX-XX"},"strain_display":{"value":"Nigeria/MT903337/2018-XX-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A146894-","A146896-","A146901-","A146906-","A146908-","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","G172784A","T181577C"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"OP535318","node_attrs":{"div":12,"accession":"OP535318","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2017_5227"},"date":{"value":"2017-12-XX"},"strain_display":{"value":"Nigeria/OP535318/2017-12-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-608T","C23311T","G75512A","G124715A","-146895T","-146897T","-146898T","-146899T","-146900T","-146902T","-146903T","-146904T","-146905T","-146907T","-146909T","-146910T","-146911T","-146912T","G162165A","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","-196616A"],"OPG039":["E270K"],"OPG095":["R237K"],"OPG145":["D257N"]},"labels":{"aa":"OPG039: E270K; OPG095: R237K; OPG145: D257N"}}},{"name":"OP535326","node_attrs":{"div":14,"accession":"OP535326","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2018_5315"},"date":{"value":"2018-06-XX"},"strain_display":{"value":"Nigeria/OP535326/2018-06-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C23000T","G29826A","C109667T","A136552-","T136553-","C136554-","-146895T","-146897T","-146898T","-146899T","-146900T","-146902T","-146903T","-146904T","-146905T","-146907T","-146909T","-146910T","-146911T","-146912T","G147459A","G155644A","G177009A","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG038":["G54S"],"OPG047":["R457C"],"OPG153":["D385-"],"OPG205":["E452K"]},"labels":{"aa":"OPG038: G54S; OPG047: R457C; OPG153: D385-; OPG205: E452K"}}},{"name":"NODE_0000005","node_attrs":{"div":17,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["T607-","C101683T","C127245T","T157146A","T158362-","T158506G","T158508G","T158517G","G158527A","G178814A","G178988A","A196615-"],"OPG149":["S17L"]},"labels":{"aa":"OPG149: S17L"}},"children":[{"name":"OP535334","node_attrs":{"div":17,"accession":"OP535334","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2018_5223"},"date":{"value":"2018-02-XX"},"strain_display":{"value":"Nigeria/OP535334/2018-02-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-146895T","-146897T","-146898T","-146899T","-146900T","-146902T","-146903T","-146904T","-146905T","-146907T","-146909T","-146910T","-146911T","-146912T","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-"]}}},{"name":"OP535314","node_attrs":{"div":17,"accession":"OP535314","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2018_5220"},"date":{"value":"2018-01-XX"},"strain_display":{"value":"Nigeria/OP535314/2018-01-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A146894-","A146896-","A146901-","A146906-","A146908-","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}}]}]},{"name":"NODE_0000006","node_attrs":{"div":11,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["C8385T","G37209A","G43118A","G48180A","C113841T","A136552-","T136553-","C136554-","C146607T","-146895T","-146897T","-146898T","-146899T","-146900T","-146902T","-146903T","-146904T","-146905T","-146907T","-146909T","-146910T","-146911T","-146912T","T169721-","A169723-","A169725-","T169726-","A169727-","A169729-","A169731-","T169732-","A179198-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-"],"OPG056":["S609F"],"OPG133":["G619E"],"OPG153":["D385-"],"OPG170":["E58K"]},"labels":{"aa":"OPG056: S609F; OPG133: G619E; OPG153: D385-; OPG170: E58K"}},"children":[{"name":"OP535328","node_attrs":{"div":11,"accession":"OP535328","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.,Howard,D.,Sheth,M.,Seabolt,M.H.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"lineage":{"value":"A"},"strain":{"value":"MPXV_Nigeria_2018_5306"},"date":{"value":"2018-03-XX"},"strain_display":{"value":"Nigeria/OP535328/2018-03-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C169722-","G169724-","C169728-","G169730-","C179199-","C179208-","C179217-"],"OPG197":["S18-","D19-","T20-","D21-"]},"labels":{"aa":"OPG197: S18-, D19-, T20-, D21-"}}},{"name":"NODE_0000007","node_attrs":{"div":12,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["G29889A","T76087-","A89106-","-169721T","-169723A","-169725A","-169726T","-169727A","-169729A","-169731A","-169732T","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T"],"OPG047":["P436S"]},"labels":{"aa":"OPG047: P436S"}},"children":[{"name":"NODE_0000008","node_attrs":{"div":15,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-","C40251T","C63801T","T121121-","G162243A","-196616A"],"OPG058":["D62N"],"OPG083":["E306K"]},"labels":{"aa":"OPG058: D62N; OPG083: E306K"}},"children":[{"name":"OP612684","node_attrs":{"div":18,"accession":"OP612684","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A"},"strain":{"value":"MPXV/046/19"},"date":{"value":"2019-05-XX"},"strain_display":{"value":"Nigeria/OP612684/2019-05-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C92830T","A136543-","T136544-","C136545-","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","-173288A","-173289T","G180656A","G186423A","-196617A"],"OPG113":["S367F"],"OPG153":["D382-","D383-","D384-"],"OPG209":["D47N"],"OPG210":["E1690K"]},"labels":{"aa":"OPG113: S367F; OPG153: D382-, D383-, D384-; OPG209: D47N; OPG210: E1690K"}}},{"name":"OP612680","node_attrs":{"div":17,"accession":"OP612680","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A"},"strain":{"value":"MPXV/021/19"},"date":{"value":"2019-04-01"},"strain_display":{"value":"Nigeria/OP612680/2019-04-01"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C63264T","-89106A","T104748C","T133098-","T133099-","T133100-","T133101-","T133102-","T187080-"],"OPG123":["D108G"]},"labels":{"aa":"OPG123: D108G"}}}]},{"name":"NODE_0000009","node_attrs":{"div":15,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","C28164T","C87027T","G121454A"],"OPG044":["S25F"]},"labels":{"aa":"OPG044: S25F"}},"children":[{"name":"OP612678","node_attrs":{"div":18,"accession":"OP612678","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A"},"strain":{"value":"MPXV/017/19"},"date":{"value":"2019-03-14"},"strain_display":{"value":"Nigeria/OP612678/2019-03-14"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G46685A","G144659A","G165688A","T187080-","A196614-","A196615-"],"OPG167":["S250F"]},"labels":{"aa":"OPG167: S250F"}}},{"name":"NODE_0000010","node_attrs":{"div":17,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["G3531A","-76087T","T151621G","T179068A","-196616A","-196617A"],"OPG178":["F38C"]},"labels":{"aa":"OPG178: F38C"}},"children":[{"name":"OP612675","node_attrs":{"div":18,"accession":"OP612675","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A"},"strain":{"value":"MPXV/007/19"},"date":{"value":"2019-01-30"},"strain_display":{"value":"Nigeria/OP612675/2019-01-30"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T4676C","-89106A","-136552A","-136553T","-136554C","C193679T"]}}},{"name":"OP612676","node_attrs":{"div":17,"accession":"OP612676","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A"},"strain":{"value":"MPXV/013/19"},"date":{"value":"2019-02-20"},"strain_display":{"value":"Nigeria/OP612676/2019-02-20"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A19360-","A23252-","T133100-","T133101-","T133102-","A138474-","A156769-","T163332-","A173514-","A173515-","G173516-","A173517-","A173518-","G173519-","A173520-","C173521-","G173522-","A173523-","G173524-","G173525-","A173526-","C173527-","G173528-","G173529-","A173530-","G173531-","A173532-","C173533-","G173534-","G173535-","T173536-","A173537-","G173538-","A173539-","A173540-","T173541-","A173542-","A173543-","T179072A"]}}}]}]}]}]},{"name":"NODE_0000011","node_attrs":{"div":21,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-","C13298T","C18792T","C30636T","C34472T","C34578T","G80099A","G93387A","G114659A","G124031A","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","-146895T","-146897T","-146898T","-146899T","-146900T","-146902T","-146903T","-146904T","-146905T","-146907T","-146909T","-146910T","-146911T","-146912T","C148529-","A148530-","T148531-","A148532-","T148533-","C148534-","A148535-","G149265A","C149872T","G154015A","C161953T","C165782T","G168205A","C177720T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A196614-","A196615-"],"OPG031":["D13N"],"OPG047":["D187N"],"OPG053":["G38E"],"OPG113":["E553K"],"OPG145":["D29N"],"OPG153":["D383-","D384-","D385-"],"OPG174":["S44L","D288-","M289-"],"OPG176":["Q22*"],"OPG180":["D442N"],"OPG188":["H120Y"],"OPG190":["P221S"],"OPG205":["R689C"]},"labels":{"aa":"OPG031: D13N; OPG047: D187N; OPG053: G38E; OPG113: E553K; OPG145: D29N; OPG153: D383-, D384-, D385-; OPG174: S44L, D288-, M289-; OPG176: Q22*; OPG180: D442N; OPG188: H120Y; OPG190: P221S; OPG205: R689C","clade":"A.2"}},"children":[{"name":"ON675438","node_attrs":{"div":43,"accession":"ON675438","author":{"author":"Gigante,C.M.,Griffin-Thomas,L.A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Crain,J.,Li,Y.","value":"Gigante,C.M.,Griffin-Thomas,L.A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Crain,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A.2"},"strain":{"value":"MPXV_USA_2022_VA001"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/ON675438/2022-05-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-606T","-607T","G11332A","G12099A","C13648T","C15105T","C16227T","C29887T","C42101T","G64216A","G75614A","C117119T","C128534T","G130454A","C134442T","C142918T","G144446A","C156429T","C164832T","C168532T","G174610A","A175231-","T175232-","C175233-","G175234-","T175235-","A175236-","G175237-","T175238-","A175239-","T175240-","C175241-","A175242-","A175243-","G175244-","A175245-","T175246-","G175247-","T175248-","A175249-","A175250-","A175251-","A175252-","T175253-","A175254-","C175255-","T175256-","T175257-","A175258-","C175259-","G175260-","G175261-","T175262-","T175263-","A175264-","T175265-","A175266-","C175267-","C175268-","G175269-","T175270-","C175271-","A175272-","C175273-","A175274-","A175275-","G175276-","A175277-","C175278-","C175279-","A175280-","C175281-","A175282-","G175283-","G175284-","T175285-","T175286-","T175287-","A175288-","A175289-","A175290-","C175291-","T175292-","A175293-","A175294-","T175295-","A175296-","C175297-","T175298-","A175299-","G175300-","A175301-","T175302-","C175303-","C175304-","G175305-","A175306-","A175307-","A175308-","A175309-","T175310-","C175311-","A175312-","A175313-","C175314-","G175315-","T175316-","A175317-","A175318-","C175319-","G175320-","A175321-","T175322-","A175323-","G175324-","G175325-","A175326-","G175327-","A175328-","A175329-","C175330-","C175331-","T175332-","G175333-","C175334-","C175335-","A175336-","A175337-","T175338-","A175339-","T175340-","A175341-","A175342-","C175343-","A175344-","T175345-","G175346-","C175347-","A175348-","G175349-","T175350-","G175351-","C175352-","T175353-","G175354-","T175355-","G175356-","T175357-","C175358-","A175359-","A175360-","C175361-","G175362-","T175363-","C175364-","A175365-","T175366-","T175367-","A175368-","T175369-","T175370-","T175371-","G175372-","T175373-","C175374-","G175375-","A175376-","C175377-","G175378-","A175379-","T175380-","G175381-","T175382-","A175383-","C175384-","T175385-","G175386-","A175387-","T175388-","T175389-","G175390-","A175391-","A175392-","T175393-","G175394-","G175395-","G175396-","A175397-","A175398-","A175399-","A175400-","T175401-","C175402-","C175403-","A175404-","T175405-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A179628G","C179853T","G188544A","-196614A"],"OPG023":["R268*"],"OPG025":["D55N","M540I"],"OPG027":["D51N"],"OPG062":["S52L"],"OPG096":["D10N"],"OPG151":["E511K"],"OPG166":["D17N"],"OPG204":["E27K","I234-","V235-","V236-","S237-","R238-","C239-","K240-","I241-","L242-","T243-","V244-","I245-","P246-","S247-","Q248-","D249-","H250-","R251-","F252-","K253-","L254-","I255-","L256-","D257-","P258-","K259-","I260-","N261-","V262-","T263-","I264-","G265-","E266-","P267-","A268-","N269-","I270-","T271-","C272-","S273-","A274-","V275-","S276-","T277-","S278-","L279-","F280-","V281-","D282-","D283-","V284-","L285-","I286-","E287-","W288-","E289-","N290-","P291-","S292-"]},"labels":{"aa":"OPG023: R268*; OPG025: D55N, M540I; OPG027: D51N; OPG062: S52L; OPG096: D10N; OPG151: E511K; OPG166: D17N; OPG204: E27K, I234-, V235-, V236-, S237-, R238-, C239-, K240-, I241-, L242-, T243-, V244-, I245-, P246-, S247-, Q248-, D249-, H250-, R251-, F252-, K253-, L254-, I255-, L256-, D257-, P258-, K259-, I260-, N261-, V262-, T263-, I264-, G265-, E266-, P267-, A268-, N269-, I270-, T271-, C272-, S273-, A274-, V275-, S276-, T277-, S278-, L279-, F280-, V281-, D282-, D283-, V284-, L285-, I286-, E287-, W288-, E289-, N290-, P291-, S292-"}}},{"name":"OP612689","node_attrs":{"div":22,"accession":"OP612689","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.2"},"strain":{"value":"MPXV/111/19"},"date":{"value":"2019-12-17"},"strain_display":{"value":"Nigeria/OP612689/2019-12-17"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G144876A","G173355-","A173356-","G173357-","G173358-","T173359-","A173360-","C173361-","G173362-","G173363-","G173364-","A173365-","T173366-","A173367-","G173368-","A173369-","A173370-","T173371-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG167":["P178S"]},"labels":{"aa":"OPG167: P178S"}}},{"name":"NODE_0000012","node_attrs":{"div":36,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.3"}},"branch_attrs":{"mutations":{"nuc":["G2752A","G39173A","C57284T","G61844A","C74226T","G118739A","C146223T","G148427A","G150800A","G168365A","G170317A","G172527A","C175759T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G189417A","C189474T","C194458T"],"OPG075":["R72K"],"OPG170":["D186N"],"OPG195":["E46K"],"OPG198":["D94N"],"OPG205":["A35V"]},"labels":{"aa":"OPG075: R72K; OPG170: D186N; OPG195: E46K; OPG198: D94N; OPG205: A35V","clade":"A.2.3"}},"children":[{"name":"ON676707","node_attrs":{"div":39,"accession":"ON676707","author":{"author":"Gigante,C.M.,Stringer,J.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Schulte,J.,Li,Y.","value":"Gigante,C.M.,Stringer,J.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Schulte,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A.2.3"},"strain":{"value":"MPXV_USA_2021_TX"},"date":{"value":"2021-07-XX"},"strain_display":{"value":"USA/ON676707/2021-07-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-606T","C100640T","G142636A","C186104T","-196614A"]}}},{"name":"OP555515","node_attrs":{"div":49,"accession":"OP555515","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"A.2.3"},"strain":{"value":"Monkeypox/PT0428/2022"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Portugal/OP555515/2022-08-01"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C30669T","C45028T","G49377A","G95355A","C121320T","G136132A","-136546A","-136547T","-136548C","G142265A","C159143T","C162264T","C170573T","C180686T","C181216T","G188229A"],"OPG047":["E176K"],"OPG064":["E291K"],"OPG068":["D393N"],"OPG139":["A17T"],"OPG153":["-383D"],"OPG163":["D22N"],"OPG185":["S76F"],"OPG198":["S179L"],"OPG209":["Q57*"]},"labels":{"aa":"OPG047: E176K; OPG064: E291K; OPG068: D393N; OPG139: A17T; OPG153: -383D; OPG163: D22N; OPG185: S76F; OPG198: S179L; OPG209: Q57*"}}}]},{"name":"NODE_0000013","node_attrs":{"div":41,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.2"}},"branch_attrs":{"mutations":{"nuc":["G11948A","C14790T","G21991A","G23118A","G38923A","G39515A","G56546A","G57786A","G93312A","C103019T","C112470T","C124129T","C127906T","G135303A","G145902A","C149365T","G155611A","G158424A","G162640A","G186984A"],"OPG023":["S318F"],"OPG025":["D160N"],"OPG037":["S148L"],"OPG056":["R38C"],"OPG113":["V528I"],"OPG122":["H198Y"],"OPG132":["M357I"],"OPG150":["S43L"],"OPG153":["D382-"],"OPG174":["G11R"],"OPG188":["G349S"],"OPG210":["D1877N"]},"labels":{"aa":"OPG023: S318F; OPG025: D160N; OPG037: S148L; OPG056: R38C; OPG113: V528I; OPG122: H198Y; OPG132: M357I; OPG150: S43L; OPG153: D382-; OPG174: G11R; OPG188: G349S; OPG210: D1877N","clade":"A.2.2"}},"children":[{"name":"OP422632","node_attrs":{"div":45,"accession":"OP422632","author":{"author":"Martin,F.,Anges,Y.,Benjamin,H.,Amadou,S.A.,Ousmane,F.","value":"Martin,F.,Anges,Y.,Benjamin,H.,Amadou,S.A.,Ousmane,F."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Benin"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institut Pasteur de Dakar, Virology Department"},"lineage":{"value":"A.2.2"},"strain":{"value":"MPXV-SEN0022"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Benin/OP422632/2022-06-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T4619C","C4623-","T4624-","T4625-","T4626-","T4627-","T4628-","C4629-","A4630-","T4631-","A4632-","A4633-","T4634-","T4635-","A4636-","G4637-","A4638-","G4639-","A4640-","A4641-","A4642-","A4643-","A4644-","G4645-","A4646-","T4647-","C4648-","A4649-","A4650-","G4651-","G4652-","T4653-","A4654-","T4655-","A4656-","A4657-","A4658-","A4659-","A4660-","T4661-","T4662-","A4663-","G4664-","A4665-","A4666-","G4667-","T4668-","G4669-","T4670-","T4671-","A4672-","G4673-","A4674-","C4675-","T4676-","A4677-","T4678-","A4679-","A4680-","C32643T","-136546A","-136547T","-136548C","-136549A","-136550T","-136551C","-136552A","-136553T","-136554C","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","G146913-","T146914-","A146915-","-148529C","-148530A","-148531T","-148532A","-148533T","-148534C","-148535A","C156429T","G172501A","T196689-"],"OPG049":["R170K"],"OPG153":["-382D","-383D","-384D","-385D"],"OPG174":["-288D","-289M"],"OPG200":["E118K"]},"labels":{"aa":"OPG049: R170K; OPG153: -382D, -383D, -384D, -385D; OPG174: -288D, -289M; OPG200: E118K"}}},{"name":"OP450997","node_attrs":{"div":48,"accession":"OP450997","author":{"author":"Gigante,C.M.,Xia,D.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y.","value":"Gigante,C.M.,Xia,D.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"A.2.2"},"strain":{"value":"MPXV_USA_2022_PA0016"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OP450997/2022-07-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G451A","G20576A","C20581T","G67351A","G78259A","G94479A","C133402T","A136543-","T136544-","C136545-","C176148T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C196759T"],"OPG036":["E162K"],"OPG085":["S394F"],"OPG205":["H165Y"]},"labels":{"aa":"OPG036: E162K; OPG085: S394F; OPG205: H165Y"}}},{"name":"NODE_0000014","node_attrs":{"div":46,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.2"}},"branch_attrs":{"mutations":{"nuc":["C13686T","C21861T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G151112A","G174721A","C188491T"],"OPG025":["E528K"],"OPG037":["M191I"],"OPG204":["A64T"]},"labels":{"aa":"OPG025: E528K; OPG037: M191I; OPG204: A64T"}},"children":[{"name":"OP331336","node_attrs":{"div":50,"accession":"OP331336","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"A.2.2"},"strain":{"value":"MPXV_UK_2022_9000166"},"date":{"value":"2022-06-29"},"strain_display":{"value":"United Kingdom/OP331336/2022-06-29"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C27826T","G59282A","C65743A","G85356A","A136543-","T136544-","C136545-"],"OPG043":["E44K"],"OPG084":["P341H"],"OPG106":["S48F"]},"labels":{"aa":"OPG043: E44K; OPG084: P341H; OPG106: S48F"}}},{"name":"OR113690","node_attrs":{"div":56,"accession":"OR113690","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Austria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"lineage":{"value":"A.2.2"},"strain":{"value":"hMPXV/Austria/MUW1607960/2023"},"date":{"value":"2023-04-05"},"strain_display":{"value":"Austria/OR113690/2023-04-05"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C18102T","C52429T","C86957T","G97318A","C121394T","G129982A","-136546A","-136547T","-136548C","-136549A","-136552A","-136553T","-136554C","G146714A","C148895A","G165892A","G175471A"],"OPG031":["D243N"],"OPG108":["D35N"],"OPG117":["D424N"],"OPG170":["A22V"],"OPG174":["M167I"],"OPG204":["E314K"]},"labels":{"aa":"OPG031: D243N; OPG108: D35N; OPG117: D424N; OPG170: A22V; OPG174: M167I; OPG204: E314K"}}}]}]},{"name":"NODE_0000015","node_attrs":{"div":22,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2"}},"branch_attrs":{"mutations":{"nuc":["-606T","-607T","-608T","C25072T","A136543-","T136544-","C136545-"],"OPG040":["R136Q"],"OPG153":["D382-"]},"labels":{"aa":"OPG040: R136Q; OPG153: D382-"}},"children":[{"name":"OP612691","node_attrs":{"div":24,"accession":"OP612691","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.2"},"strain":{"value":"MPXV/191/20"},"date":{"value":"2020-01-XX"},"strain_display":{"value":"Nigeria/OP612691/2020-01-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-609T","C90329T","C132520T","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG111":["S22L"]},"labels":{"aa":"OPG111: S22L"}}},{"name":"NODE_0000016","node_attrs":{"div":35,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["G36898A","G42183A","C42903T","G50346A","C54268T","C73616T","G79406A","G105746A","A140492C","C142498T","C157737T","C161152T","A169763-","C169764-","A169765-","G169766-","A169767-","T169768-","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","C179537T","-196614A","-196615A"],"OPG062":["M79I"],"OPG063":["M262I"],"OPG069":["D121N"],"OPG102":["D108N"],"OPG160":["S195A"],"OPG197":["T32-","D33-","T34-","D35-"],"OPG208":["S91L"]},"labels":{"aa":"OPG062: M79I; OPG063: M262I; OPG069: D121N; OPG102: D108N; OPG160: S195A; OPG197: T32-, D33-, T34-, D35-; OPG208: S91L","clade":"A.2.1"}},"children":[{"name":"NODE_0000017","node_attrs":{"div":36,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["T95936A"],"OPG116":["D192E"]},"labels":{"aa":"OPG116: D192E"}},"children":[{"name":"ON674051","node_attrs":{"div":38,"accession":"ON674051","author":{"author":"Gigante,C.M.,Lee,P.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A.2.1"},"strain":{"value":"MPXV_USA_2022_FL001"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/ON674051/2022-05-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T608-","C112544T","G163540A"],"OPG132":["D333N"],"OPG189":["E70K"]},"labels":{"aa":"OPG132: D333N; OPG189: E70K"}}},{"name":"OR459777","node_attrs":{"div":44,"accession":"OR459777","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"South Korea"},"clade_membership":{"value":"IIb"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"lineage":{"value":"A.2.1"},"strain":{"value":"MPXV-ROK-P004-2022"},"date":{"value":"2022-11-22"},"strain_display":{"value":"South Korea/OR459777/2022-11-22"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-609T","A46522G","G52289A","G67261A","C72231T","C115379T","C135822T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G181947A","G182189A","-196616A","-196617A"],"OPG071":["T717I"],"OPG085":["S424L"],"OPG210":["D198N"]},"labels":{"aa":"OPG071: T717I; OPG085: S424L; OPG210: D198N"}}}]},{"name":"NODE_0000018","node_attrs":{"div":36,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C184924T","-196616A","-196617A"],"OPG210":["S1190L"]},"labels":{"aa":"OPG210: S1190L"}},"children":[{"name":"OP936000","node_attrs":{"div":45,"accession":"OP936000","author":{"author":"Nguyen,D.T.,Le,H.M.,Huynh,H.T.T.,Tang,T.C.,Le,N.H.,Nguyen,H.H.,Nghiem,N.M.,Nguyen,H.T.T.,Vo,Q.T.,Vu,T.T.K.,Nguyen,T.T.,Phan,T.V.,Nguyen,T.L.N.,Le,T.M.,Vo,Q.M.,Dinh,M.N.H.,Nguyen,P.T.,Tran,P.T.L.,Tran,T.T.T.,Pham,T.T.N.,Nguyen,T.H.,Truong,L.T.T.,Nguyen,H.N.T.,Tran,T.T.,Le,K.T.T.,Lam,Y.M.,Thwaites,G.,Thwaites,L.,Nguyen,C.V.V.,Nguyen,A.T.,Le,T.V.","value":"Nguyen,D.T.,Le,H.M.,Huynh,H.T.T.,Tang,T.C.,Le,N.H.,Nguyen,H.H.,Nghiem,N.M.,Nguyen,H.T.T.,Vo,Q.T.,Vu,T.T.K.,Nguyen,T.T.,Phan,T.V.,Nguyen,T.L.N.,Le,T.M.,Vo,Q.M.,Dinh,M.N.H.,Nguyen,P.T.,Tran,P.T.L.,Tran,T.T.T.,Pham,T.T.N.,Nguyen,T.H.,Truong,L.T.T.,Nguyen,H.N.T.,Tran,T.T.,Le,K.T.T.,Lam,Y.M.,Thwaites,G.,Thwaites,L.,Nguyen,C.V.V.,Nguyen,A.T.,Le,T.V."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Vietnam"},"clade_membership":{"value":"IIb"},"institution":{"value":"EI group, Oxford University Clinica Research Unit"},"lineage":{"value":"A.2.1"},"strain":{"value":"Mpox-HCMC-M157"},"date":{"value":"2022-09-26"},"strain_display":{"value":"Vietnam/OP936000/2022-09-26"},"region":{"value":"Asia"}},"branch_attrs":{"mutations":{"nuc":["T647-","G648-","C32252T","G51559A","A86823T","G103706A","C152033T","T167015G","A167020T","A167021-","C167022-","G167029C","A187574C"]}}},{"name":"NODE_0000019","node_attrs":{"div":37,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["G43103A","A136540-","T136541-","C136542-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"],"OPG063":["P196S"],"OPG153":["D381-"]},"labels":{"aa":"OPG063: P196S; OPG153: D381-"}},"children":[{"name":"OR455100","node_attrs":{"div":43,"accession":"OR455100","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"A.2.1"},"strain":{"value":"MpxV/human/USA/WA-UW-081251/2023"},"date":{"value":"2023-08-XX"},"strain_display":{"value":"USA/OR455100/2023-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-609T","C29438T","G58696A","G120906A","G147352A","G178102A","C187942T","A192392-","A192393-","A192394-","T192395-","G192396-","A192397-","G192398-","T192399-","T192400-","A192401-","A192402-","T192403-","A192404-","G192405-"],"OPG046":["V98I"],"OPG078":["S39L"],"OPG138":["S76F"],"OPG171":["R122K"]},"labels":{"aa":"OPG046: V98I; OPG078: S39L; OPG138: S76F; OPG171: R122K"}}},{"name":"NODE_0000020","node_attrs":{"div":39,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.2.1"}},"branch_attrs":{"mutations":{"nuc":["G30868A","G102599A","-133098T","-133099T","-133100T","-169763A","-169764C","-169765A","-169766G","-169767A","-169768T","-169769A","-169770C","-169771A","-169772G","-169773A","-169774T"],"OPG122":["D58N"],"OPG197":["-32T","-33D","-34T","-35D"]},"labels":{"aa":"OPG122: D58N; OPG197: -32T, -33D, -34T, -35D"}},"children":[{"name":"OP331335","node_attrs":{"div":40,"accession":"OP331335","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"A.2.1"},"strain":{"value":"MPXV_UK_2022_9000155"},"date":{"value":"2022-06-03"},"strain_display":{"value":"United Kingdom/OP331335/2022-06-03"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T607-","T608-","-133101T","-133102T","-136540A","-136541T","-136542C","-136543A","-136544T","-136545C","-136546A","-136547T","-136548C","-136549A","-136550T","-136551C","-136552A","-136553T","-136554C","C164210T","-174531G","-174532A","-174533T","-174534G","-174535A","-174536A"],"OPG153":["-381D","-382D","-383D","-384D","-385D"],"OPG189":["S293L"]},"labels":{"aa":"OPG153: -381D, -382D, -383D, -384D, -385D; OPG189: S293L"}}},{"name":"OP605572","node_attrs":{"div":39,"accession":"OP605572","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"lineage":{"value":"A.2.1"},"strain":{"value":"Slovenia-MPXV-30-2022"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Slovenia/OP605572/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C165-","A196625-","T196626-","T196627-"]}}}]}]}]}]}]}]},{"name":"NODE_0000021","node_attrs":{"div":6,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A"}},"branch_attrs":{"mutations":{"nuc":["A173314-","T173315-","A173316-","T173317-","C187428T"]}},"children":[{"name":"NODE_0000022","node_attrs":{"div":14,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["G56968A","G61844A","C84008T","G96841A","C100971T","C134078T","C151050T","G188889-"],"OPG074":["S53L"],"OPG117":["D265N"],"OPG120":["E260K"]},"labels":{"aa":"OPG074: S53L; OPG117: D265N; OPG120: E260K","clade":"A.3"}},"children":[{"name":"MG693723","node_attrs":{"div":27,"accession":"MG693723","author":{"author":"Faye,O.,Pratt,C.B.,Faye,M.,Fall,G.,Chitty,J.A.,Diagne,M.M.,Wiley,M.R.,Yinka-Ogunleye,A.F.,Aruna,S.,Etebu,E.N.,Aworabhi,N.,Ogoina,D.,Numbere,W.,Mba,N.,Palacios,G.,Sall,A.A.,Ihekweazu,C.,Diagne,M.,Palacios,G.F.,Sall,A.","value":"Faye,O.,Pratt,C.B.,Faye,M.,Fall,G.,Chitty,J.A.,Diagne,M.M.,Wiley,M.R.,Yinka-Ogunleye,A.F.,Aruna,S.,Etebu,E.N.,Aworabhi,N.,Ogoina,D.,Numbere,W.,Mba,N.,Palacios,G.,Sall,A.A.,Ihekweazu,C.,Diagne,M.,Palacios,G.F.,Sall,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"USAMRIID, Center for Genome Sciences"},"lineage":{"value":"A.3"},"strain":{"value":"MPXV_Nig_2017_297957"},"date":{"value":"2017-XX-XX"},"strain_display":{"value":"Nigeria/MG693723/2017-XX-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A8143-","G8144-","C8145-","A8146-","T8147-","A8148-","T8149-","T8150-","A8151-","A8152-","A8153-","G8154-","T8155-","A8156-","A8157-","A8158-","A8159-","T8160-","C8161-","T8162-","A8163-","G8164-","T8165-","T8166-","A8167-","C8168-","C8169-","T8170-","T8171-","G8172-","A8173-","A8174-","A8175-","A8176-","T8177-","G8178-","A8179-","A8180-","T8181-","A8182-","C8183-","A8184-","G8185-","T8186-","G8187-","G8188-","G8189-","T8190-","G8191-","G8192-","T8193-","T8194-","C8195-","C8196-","G8197-","T8198-","A8199-","T8200-","C8201-","A8202-","C8203-","C8204-","A8205-","G8206-","T8207-","A8208-","A8209-","G8210-","A8211-","A8212-","C8213-","A8214-","T8215-","A8216-","A8217-","T8218-","A8219-","G8220-","T8221-","C8222-","G8223-","A8224-","A8225-","T8226-","A8227-","C8228-","A8229-","G8230-","T8231-","A8232-","T8233-","C8234-","C8235-","G8236-","A8237-","T8238-","T8239-","G8240-","A8241-","G8242-","A8243-","T8244-","T8245-","T8246-","T8247-","G8248-","C8249-","A8250-","T8251-","A8252-","C8253-","A8254-","A8255-","T8256-","A8257-","C8258-","T8259-","A8260-","G8261-","T8262-","C8263-","T8264-","A8265-","G8266-","A8267-","A8268-","A8269-","G8270-","A8271-","A8272-","A8273-","T8274-","T8275-","T8276-","G8277-","T8278-","A8279-","A8280-","T8281-","C8282-","A8283-","T8284-","C8285-","C8286-","T8287-","C8288-","T8289-","G8290-","T8291-","G8292-","A8293-","C8294-","A8295-","G8296-","G8297-","A8298-","G8299-","T8300-","C8301-","C8302-","A8303-","T8304-","A8305-","T8306-","A8307-","T8308-","C8309-","T8310-","G8311-","T8312-","A8313-","T8314-","C8315-","A8316-","T8317-","C8318-","G8319-","T8320-","C8321-","T8322-","A8323-","G8324-","T8325-","T8326-","T8327-","T8328-","T8329-","A8330-","T8331-","C8332-","A8333-","G8334-","T8335-","G8336-","T8337-","C8338-","C8339-","T8340-","A8341-","T8342-","G8343-","C8344-","T8345-","A8346-","T8347-","A8348-","T8349-","T8350-","C8351-","C8352-","T8353-","G8354-","T8355-","T8356-","A8357-","T8358-","C8359-","A8360-","T8361-","C8362-","A8363-","T8364-","T8365-","A8366-","G8367-","T8368-","T8369-","A8370-","A8371-","T8372-","G8373-","A8374-","A8375-","A8376-","A8377-","T8378-","A8379-","A8380-","C8381-","T8382-","C8383-","T8384-","C8385-","G8386-","T8387-","G8388-","C8389-","T8390-","T8391-","C8392-","A8393-","G8394-","A8395-","A8396-","A8397-","A8398-","G8399-","T8400-","C8401-","A8402-","A8403-","A8404-","T8405-","A8406-","T8407-","T8408-","G8409-","T8410-","A8411-","T8412-","C8413-","C8414-","A8415-","T8416-","A8417-","C8418-","A8419-","T8420-","A8421-","T8422-","A8423-","T8424-","C8425-","T8426-","C8427-","C8428-","A8429-","A8430-","A8431-","A8432-","C8433-","T8434-","A8435-","T8436-","C8437-","A8438-","C8439-","T8440-","T8441-","A8442-","T8443-","A8444-","C8445-","G8446-","T8447-","T8448-","T8449-","A8450-","T8451-","C8452-","T8453-","T8454-","T8455-","A8456-","A8457-","C8458-","G8459-","A8460-","A8461-","C8462-","A8463-","T8464-","A8465-","T8466-","A8467-","C8468-","C8469-","T8470-","A8471-","G8472-","A8473-","T8474-","G8475-","G8476-","T8477-","T8478-","A8479-","T8480-","T8481-","T8482-","A8483-","C8484-","T8485-","A8486-","A8487-","C8488-","A8489-","G8490-","A8491-","C8492-","A8493-","T8494-","T8495-","T8496-","T8497-","T8498-","T8499-","C8500-","A8501-","A8502-","G8503-","A8504-","T8505-","C8506-","T8507-","A8508-","T8509-","T8510-","G8511-","A8512-","C8513-","A8514-","A8515-","T8516-","A8517-","A8518-","C8519-","T8520-","C8521-","C8522-","T8523-","A8524-","T8525-","A8526-","G8527-","T8528-","T8529-","T8530-","C8531-","C8532-","A8533-","C8534-","A8535-","T8536-","C8537-","A8538-","A8539-","C8540-","C8541-","A8542-","A8543-","G8544-","T8545-","A8546-","A8547-","T8548-","G8549-","A8550-","T8551-","C8552-","A8553-","T8554-","C8555-","T8556-","A8557-","T8558-","T8559-","G8560-","T8561-","T8562-","A8563-","T8564-","A8565-","T8566-","A8567-","A8568-","C8569-","A8570-","A8571-","T8572-","A8573-","A8574-","C8575-","A8576-","T8577-","A8578-","A8579-","C8580-","T8581-","C8582-","T8583-","T8584-","T8585-","T8586-","C8587-","C8588-","A8589-","T8590-","T8591-","T8592-","T8593-","T8594-","A8595-","T8596-","C8597-","A8598-","G8599-","T8600-","A8601-","T8602-","C8603-","T8604-","A8605-","T8606-","A8607-","T8608-","C8609-","A8610-","A8611-","C8612-","G8613-","T8614-","C8615-","G8616-","T8617-","T8618-","G8619-","T8620-","A8621-","G8622-","T8623-","G8624-","A8625-","A8626-","T8627-","A8628-","G8629-","T8630-","A8631-","G8632-","T8633-","C8634-","A8635-","T8636-","T8637-","G8638-","A8639-","T8640-","C8641-","T8642-","A8643-","T8644-","T8645-","A8646-","T8647-","A8648-","T8649-","G8650-","A8651-","A8652-","A8653-","C8654-","G8655-","G8656-","A8657-","T8658-","A8659-","T8660-","G8661-","T8662-","C8663-","T8664-","A8665-","G8666-","T8667-","T8668-","A8669-","A8670-","T8671-","A8672-","T8673-","T8674-","T8675-","T8676-","C8677-","T8678-","T8679-","T8680-","G8681-","A8682-","T8683-","T8684-","T8685-","A8686-","A8687-","A8688-","G8689-","T8690-","C8691-","T8692-","A8693-","T8694-","A8695-","G8696-","T8697-","C8698-","T8699-","T8700-","T8701-","A8702-","C8703-","A8704-","A8705-","A8706-","C8707-","A8708-","T8709-","A8710-","A8711-","T8712-","A8713-","T8714-","C8715-","C8716-","T8717-","T8718-","A8719-","T8720-","C8721-","C8722-","G8723-","A8724-","C8725-","T8726-","T8727-","T8728-","A8729-","T8730-","A8731-","T8732-","T8733-","T8734-","C8735-","C8736-","T8737-","G8738-","T8739-","A8740-","G8741-","G8742-","G8743-","T8744-","G8745-","G8746-","C8747-","A8748-","T8749-","A8750-","A8751-","T8752-","T8753-","T8754-","T8755-","A8756-","T8757-","T8758-","C8759-","T8760-","G8761-","C8762-","C8763-","T8764-","C8765-","C8766-","A8767-","C8768-","A8769-","A8770-","T8771-","C8772-","A8773-","G8774-","T8775-","G8776-","T8777-","T8778-","T8779-","C8780-","C8781-","A8782-","A8783-","A8784-","T8785-","A8786-","T8787-","A8788-","T8789-","T8790-","A8791-","C8792-","T8793-","A8794-","G8795-","A8796-","C8797-","A8798-","A8799-","T8800-","A8801-","T8802-","T8803-","C8804-","C8805-","A8806-","T8807-","A8808-","T8809-","A8810-","G8811-","T8812-","T8813-","A8814-","T8815-","T8816-","A8817-","G8818-","T8819-","T8820-","A8821-","A8822-","G8823-","G8824-","G8825-","A8826-","C8827-","C8828-","C8829-","A8830-","A8831-","T8832-","T8833-","A8834-","G8835-","A8836-","A8837-","C8838-","A8839-","C8840-","G8841-","T8842-","A8843-","C8844-","G8845-","C8846-","G8847-","C8848-","T8849-","T8850-","A8851-","T8852-","T8853-","C8854-","A8855-","T8856-","C8857-","A8858-","T8859-","T8860-","T8861-","G8862-","G8863-","A8864-","T8865-","C8866-","G8867-","T8868-","A8869-","T8870-","T8871-","T8872-","C8873-","A8874-","T8875-","A8876-","A8877-","A8878-","A8879-","G8880-","T8881-","T8882-","A8883-","T8884-","T8885-","A8886-","T8887-","G8888-","T8889-","T8890-","A8891-","T8892-","A8893-","G8894-","A8895-","T8896-","G8897-","T8898-","C8899-","A8900-","A8901-","C8902-","A8903-","C8904-","A8905-","T8906-","T8907-","C8908-","T8909-","A8910-","C8911-","A8912-","T8913-","T8914-","T8915-","T8916-","T8917-","T8918-","T8919-","A8920-","A8921-","T8922-","T8923-","G8924-","T8925-","C8926-","T8927-","A8928-","T8929-","A8930-","T8931-","A8932-","G8933-","T8934-","A8935-","T8936-","T8937-","T8938-","T8939-","T8940-","C8941-","T8942-","G8943-","A8944-","T8945-","A8946-","T8947-","T8948-","T8949-","T8950-","C8951-","T8952-","A8953-","T8954-","A8955-","A8956-","T8957-","A8958-","T8959-","C8960-","A8961-","G8962-","A8963-","A8964-","T8965-","T8966-","G8967-","T8968-","C8969-","T8970-","T8971-","C8972-","C8973-","A8974-","T8975-","A8976-","G8977-","G8978-","A8979-","A8980-","G8981-","T8982-","T8983-","G8984-","T8985-","A8986-","T8987-","A8988-","C8989-","T8990-","A8991-","T8992-","T8993-","C8994-","G8995-","G8996-","A8997-","A8998-","T8999-","C9000-","A9001-","G9002-","T9003-","T9004-","A9005-","C9006-","A9007-","T9008-","G9009-","T9010-","T9011-","T9012-","A9013-","A9014-","A9015-","T9016-","A9017-","A9018-","T9019-","T9020-","C9021-","T9022-","C9023-","T9024-","G9025-","A9026-","T9027-","G9028-","T9029-","C9030-","A9031-","T9032-","T9033-","C9034-","C9035-","T9036-","T9037-","A9038-","T9039-","A9040-","C9041-","A9042-","A9043-","T9044-","C9045-","A9046-","A9047-","A9048-","T9049-","T9050-","C9051-","A9052-","T9053-","T9054-","A9055-","T9056-","T9057-","A9058-","A9059-","A9060-","C9061-","A9062-","G9063-","T9064-","T9065-","T9066-","A9067-","A9068-","T9069-","A9070-","G9071-","T9072-","C9073-","T9074-","G9075-","T9076-","A9077-","G9078-","A9079-","C9080-","C9081-","T9082-","T9083-","T9084-","A9085-","T9086-","C9087-","G9088-","T9089-","C9090-","G9091-","T9092-","A9093-","C9094-","A9095-","T9096-","A9097-","T9098-","C9099-","C9100-","A9101-","T9102-","T9103-","G9104-","T9105-","C9106-","T9107-","T9108-","A9109-","T9110-","T9111-","A9112-","G9113-","T9114-","T9115-","A9116-","C9117-","G9118-","C9119-","T9120-","T9121-","A9122-","T9123-","T9124-","T9125-","T9126-","T9127-","A9128-","T9129-","G9130-","G9131-","G9132-","T9133-","T9134-","T9135-","T9136-","A9137-","C9138-","G9139-","T9140-","T9141-","G9142-","C9143-","T9144-","T9145-","T9146-","A9147-","T9148-","T9149-","A9150-","T9151-","A9152-","T9153-","T9154-","T9155-","T9156-","A9157-","T9158-","A9159-","A9160-","T9161-","A9162-","A9163-","T9164-","G9165-","A9166-","T9167-","T9168-","G9169-","T9170-","T9171-","T9172-","G9173-","A9174-","C9175-","A9176-","A9177-","T9178-","G9179-","T9180-","C9181-","G9182-","T9183-","A9184-","G9185-","T9186-","A9187-","T9188-","A9189-","G9190-","A9191-","T9192-","A9193-","T9194-","A9195-","T9196-","T9197-","A9198-","T9199-","T9200-","A9201-","G9202-","A9203-","G9204-","G9205-","A9206-","G9207-","G9208-","T9209-","A9210-","T9211-","A9212-","A9213-","T9214-","T9215-","A9216-","T9217-","A9218-","A9219-","A9220-","A9221-","A9222-","G9223-","T9224-","T9225-","T9226-","C9227-","T9228-","G9229-","A9230-","G9231-","T9232-","A9233-","C9234-","G9235-","A9236-","T9237-","G9238-","T9239-","T9240-","A9241-","T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","C9257-","A9258-","T9259-","T9260-","A9261-","A9262-","C9263-","A9264-","T9265-","C53702T","-146895T","-146897T","-146898T","-146899T","-146900T","-146902T","-146903T","-146904T","-146905T","-146907T","-146909T","-146910T","-146911T","-146912T","A166866-","C166867-","T166868-","G166869-","A166870-","T166871-","G166872-","A166873-","T166874-","A166875-","A166876-","T166877-","A166878-","A166879-","T166880-","G166881-","A166882-","A166883-","T166884-","T166885-","G166886-","G166887-","T166888-","G166889-","T166890-","T166891-","A166892-","A166893-","A166894-","T166895-","T166896-","T166897-","T166898-","A166899-","A166900-","A166901-","G166902-","A166903-","G166904-","T166905-","A166906-","C166907-","A166908-","C166909-","A166910-","A166911-","T166912-","T166913-","T166914-","C166915-","T166916-","A166917-","T166918-","T166919-","A166920-","T166921-","T166922-","A166923-","C166924-","A166925-","G166926-","A166927-","G166928-","T166929-","C166930-","A166931-","T166932-","G166933-","T166934-","G166935-","A166936-","C166937-","G166938-","T166939-","C166940-","G166941-","G166942-","A166943-","T166944-","T166945-","T166946-","G166947-","A166948-","T166949-","T166950-","C166951-","C166952-","A166953-","T166954-","A166955-","G166956-","A166957-","T166958-","A166959-","T166960-","A166961-","G166962-","A166963-","T166964-","G166965-","T166966-","T166967-","A166968-","T166969-","A166970-","A166971-","A166972-","C166973-","G166974-","A166975-","C166976-","T166977-","A166978-","T166979-","A166980-","A166981-","A166982-","A166983-","T166984-","T166985-","A166986-","T166987-","T166988-","G166989-","A166990-","T166991-","A166992-","T166993-","G166994-","T166995-","A166996-","T166997-","A166998-","C166999-","C168582A","C168584-","T168585-","C168586-","T168587-","G168588-","T168589-","A168590-","T168591-","T168592-","T168593-","C168594-","T168595-","G168596-","T168597-","A168598-","T168599-","A168600-","T168601-","T168602-","G168603-","T168604-","G168605-","A168606-","T168607-","C168608-","A168609-","A168610-","G168611-","A168612-","G168613-","G168614-","C168615-","G168616-","G168617-","G168618-","A168619-","G168620-","T168624G","A168626-","A168627-","A168628-","T168629-","T168630-","T168631-","G168632-","A168633-","G168634-","G168635-","A168636-","G168637-","T168638-","A168639-","T168640-","A168641-","C168642-","T168643-","C168644-","A168645-","A168646-","G168647-","A168648-","A168649-","T168650-","C168651-","A168652-","A168653-","G168654-","T168655-","G168656-","A168657-","T168658-","A168659-","T168660-","C168661-","A168662-","G168663-","T168664-","A168665-","T168666-","T168667-","A168668-","A168674-","A168675-","G168676-","T168677-","A168678-","T168679-","G168680-","A168681-","T168682-","T168683-","C168684-","A168685-","T168686-","C168687-","A168688-","T168689-","G168690-","T168691-","A168692-","T168693-","T168694-","G168695-","A168696-","T168697-","T168698-","A168699-","T168700-","G168704-","G168705-","T168706-","A168707-","T168708-","T168709-","A168710-","A168711-","T168712-","C168713-","A168714-","A168715-","A168716-","G168717-","T168718-","T168719-","T168720-","C168721-","A168722-","T168723-","G168724-","A168725-","A168726-","T168727-","T168731C","G168732A","A168734T","C168737G","G168741-","A168742-","A168743-","T168744-","A168748T","C168750G","G168755-","A168756-","T168757-","A168758-","G168759-","A168760-","G168761-","A168762-","A168763-","T168764-","C168765-","A168766-","T168767-","G168768-","C168769-","G168770-","T168771-","C168772-","A168773-","G168774-","A168775-","T168777G","C169569-","A169570-","T169571-","T169572-","T169573-","A169574-","A169575-","T169576-","A169577-","A169578-","G169579-","G169580-","A169581-","C169582-","A169583-","T169584-","T169585-","G169586-","G169587-","A169588-","T169589-","A169590-","T169591-","G169592-","T169593-","G169594-","G169595-","A169596-","A169597-","A169598-","A169599-","G169600-","T169601-","G169602-","A169603-","T169604-","G169605-","T169606-","A169607-","T169608-","G169609-","G169610-","A169611-","A169612-","G169613-","T169614-","T169615-","A169616-","G169617-","T169618-","A169619-","C169620-","A169621-","T169622-","T169623-","A169624-","T169625-","C169626-","A169627-","A169628-","C169629-","T169630-","T169631-","C169632-","T169633-","C169634-","C169635-","T169636-","T169637-","A169638-","T169639-","T169640-","G169641-","A169642-","T169643-","T169644-","G169645-","A169646-","A169647-","A169648-","A169649-","T169650-","G169651-","A169652-","A169653-","A169654-","A169655-","T169656-","A169657-","T169658-","A169659-","A169660-","A169661-","T169662-","A169663-","G169664-","T169665-","T169666-","T169667-","T169668-","T169669-","A169670-","T169671-","G169672-","T169673-","A169674-","T169675-","A169676-","G169677-","C169678-","G169679-","G169680-","T169681-","A169682-","T169683-","C169684-","T169685-","A169686-","C169687-","C169688-","C169689-","T169690-","A169691-","T169692-","A169693-","G169694-","T169695-","T169696-","T169697-","T169698-","A169699-","T169700-","T169701-","G169702-","C169703-","T169704-","T169705-","A169706-","C169707-","T169708-","A169709-","C169710-","T169711-","A169712-","A169713-","C169714-","A169715-","T169716-","G169717-","G169718-","A169719-","T169720-","T169721-","C169722-","A169723-","G169724-","A169725-","T169726-","A169727-","C169728-","A169729-","G169730-","A169731-","T169732-","A169733-","C169734-","A169735-","G169736-","A169737-","T169738-","A169739-","C169740-","A169741-","G169742-","A169743-","T169744-","A169745-","C169746-","A169747-","G169748-","A169749-","T169750-","A169751-","C169752-","A169753-","G169754-","A169755-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","T187263G","A187265-","G187266-","A187267-","A187268-","T187269-","C187270-","A187271-","T187272-","T187273-","T187274-","A187275-","T187276-","C187277-","A187278-","T187279-","A187280-","A187281-","C187282-","T187283-","A187284-","T187285-","G187286-","T187287-","T187288-","T187289-","A187290-","A187291-","T187292-","A187293-","A187294-","A187295-","T187296-","T187297-","C187298-","A187299-","T187300-","C187301-","A187302-","A187303-","C187304-","G187305-","A187306-","A187307-","T187308-","A187309-","T187310-","C187311-","G187312-","A187313-","T187314-","A187315-","A187316-","A187317-","G187318-","A187319-","C187320-","C187321-","T187322-","C187323-","T187324-","T187325-","G187326-","T187327-","A187328-","A187329-","T187330-","T187331-","C187332-","G187333-","A187334-","G187335-","T187336-","A187337-","T187338-","A187339-","G187340-","G187341-","A187342-","A187343-","G187344-","T187345-","A187346-","G187347-","T187348-","A187349-","T187350-","T187351-","A187352-","C187353-","C187354-","A187355-","T187356-","A187357-","T187358-","C187359-","A187360-","A187361-","C187362-","C187366T","A187372-","A187373-","C187374-","A187375-","A187376-","T187377-","T187378-","A187379-","C187380-","T187381-","C187382-","T187383-","A187384-","A187385-","A187386-","A187387-","C187388-","A187389-","T187390-","G187391-","A187392-","G187393-","G187394-","A187395-","T187396-","T187397-","G187398-","T187399-","A187400-","C187401-","T187402-","C187403-","C187404-","T187405-","G187406-","T187407-","C187408-","T187409-","T187410-","G187415-","G187416-","A187417-","G187418-","A187419-","T187420-","C187421-","A187422-","C187423-","T187424-","A187425-","T187426-","T187427-","T187428-","A187429-","G187430-","T187431-","C187432-","G187433-","T187434-","T187435-","G187436-","A187437-","T187438-","A187439-","A187440-","A187441-","C187442-","T187443-","A187444-","G187445-","T187446-","A187447-","A187448-","C187449-","C187450-","T187451-","C187452-","A187453-","G187454-","G187455-","T187456-","T187457-","T187458-","C187459-","T187460-","T187461-","T187462-","A187463-","C187464-","A187465-","A187466-","A187467-","C187468-","G187469-","A187470-","T187471-","A187472-","A187473-","A187474-","G187475-","T187476-","A187477-","C187478-","A187479-","A187480-","C187481-","A187482-","T187483-","C187484-","A187485-","A187486-","G187487-","A187488-","C187489-","C187490-","T187491-","C187492-","A187493-","C187494-","A187495-","A187496-","C187497-","A187498-","C187499-","A187500-","G187501-","T187502-","G187503-","C187504-","A187505-","A187506-","G187507-","A187508-","T187509-","T187510-","A187511-","A187512-","T187513-","C187514-","T187515-","A187516-","G187517-","A187518-","A187519-","A187520-","T187521-","C187522-","A187523-","A187524-","A187525-","T187526-","G187527-","T187528-","A187529-","A187530-","T187531-","T187532-","C187533-","T187534-","G187535-","G187536-","A187537-","G187538-","G187539-","C187545-","T187546-","A187547-","G187548-","A187549-","C187550-","A187551-","A187552-","C187553-","T187554-","A187555-","A187556-","C187557-","A187558-","C187559-","C187560-","C187561-","A187562-","C187563-","G187564-","G187565-","C187566-","G187567-","A187568-","A187569-","G187570-","T187571-","A187572-","T187573-","A187574-","C187575-","T187576-","T187577-","T187578-","A187579-","T187580-","G187581-","C187582-","C187583-","T187584-","C187585-","A187586-","T187587-","T187588-","C187589-","A187590-","G187591-","A187592-","A187593-","A187594-","C187595-","G187596-","G187597-","T187598-","A187599-","A187600-","C187601-","T187602-","G187603-","T187604-","A187605-","G187606-","T187607-","A187608-","G187609-","G187610-","A187611-","G187612-","A187613-","C187614-","T187615-","G187616-","T187617-","C187618-","T187619-","C187620-","T187621-","C187622-","T187623-","A187624-","A187625-","T187626-","C187627-","T187628-","C187629-","G187630-","A187631-","T187632-","G187633-","T187634-","A187635-","T187636-","A187637-","T187638-","A187639-","T187640-","A187641-","A187642-","T187643-","A187644-","T187645-","A187646-","T187647-","A187648-","C187649-","C187650-","A187651-","A187652-","T187653-","A187654-","C187655-","G187656-","G187657-","A187658-","C187659-","G187660-","C187661-","G187662-","A187663-","T187664-","A187665-","T187666-","A187667-","T187668-","T187669-","C187670-","C187671-","G187672-","A187673-","C187674-","A187675-","T187676-","G187677-","A187678-","A187679-","T187680-","G187681-","G187682-","C187683-","G187684-","T187685-","C187686-","G187687-","C187688-","T187689-","T187690-","A187691-","T187692-","C187693-","A187694-","T187695-","A187696-","T187697-","G187698-","T187699-","T187700-","A187701-","T187702-","A187703-","T187704-","C187705-","C187706-","T187707-","A187708-","A187709-","A187710-","T187711-","G187712-","T187713-","T187714-","G187715-","A187716-","T187717-","C187718-","A187719-","T187720-","A187721-","T187722-","T187723-","C187724-","C187725-","A187726-","C187727-","A187728-","A187729-","A187730-","T187731-","G187732-","A187733-","T187734-","T187735-","G187736-","T187737-","G187738-","A187739-","A187740-","C187741-","G187742-","A187743-","G187744-","A187745-","T187746-","T187747-","A187748-","A187749-","A187750-","T187751-","C187752-","A187753-","T187754-","C187755-","T187756-","A187757-","A187758-","C187759-","A187760-","A187761-","A187762-","T187763-","A187764-","A187765-","T187766-","T187767-","A187768-","G187769-","T187770-","T187771-","T187772-","T187773-","T187774-","T187775-","A187776-","T187777-","G187778-","A187779-","C187780-","A187781-","T187782-","T187783-","A187784-","A187785-","C187786-","A187787-","T187788-","A187789-","T187790-","A187791-","A187792-","T187793-","A187794-","A187795-","A187796-","T187797-","A187798-","A187799-","A187800-","T187801-","T187802-","A187803-","A187804-","T187805-","C187806-","A187807-","T187808-","T187809-","A187810-","T187811-","T187812-","G187813-","A187814-","C187815-","T187816-","T187817-","A187818-","A187819-","C187820-","G187821-","A187822-","T187823-","G187824-","A187825-","C187826-","G187827-","A187828-","A187829-","A187830-","G187831-","T187832-","T187833-","A187834-","T187835-","C187836-","A187837-","T187838-","T187839-","A187840-","T187841-","C187842-","T187843-","T187844-","A187845-","G187846-","G187847-","A187848-","T187849-","T187850-","C187851-","T187852-","T187853-","G187854-","A187855-","T187856-","T187857-","A187858-","T187859-","T187860-","A187861-","A187862-","T187863-","A187864-","C187865-","A187866-","A187867-","A187868-","T187869-","T187870-","C187871-","G187872-","T187873-","T187874-","T188117-","T188118-","A188119-","T188120-","C188121-","G188122-","T188123-","C188124-","T188125-","C188126-","C188127-","T188128-","T188129-","A188130-","A188131-","A188132-","G188133-","C188134-","T188135-","T188136-","C188137-","T188138-","G188139-","A188140-","T188141-","G188142-","G188143-","T188144-","A188145-","A188146-","C188147-","T188148-","G188149-","T188150-","G188151-","T188152-","T188153-","A188154-","C188155-","A188156-","T188157-","G188158-","T188159-","G188160-","C188161-","T188162-","C188163-","C188164-","T188165-","A188166-","A188167-","A188168-","A188169-","C188170-","A188171-","A188172-","A188173-","A188174-","T188175-","A188176-","T188177-","G188178-","G188179-","T188180-","C188181-","G188182-","T188183-","G188184-","T188185-","G188186-","T188187-","A188188-","C188189-","G188190-","G188191-","A188192-","A188193-","A188194-","G188195-","A188196-","A188197-","A188198-","G188199-","G188200-","A188201-","G188202-","A188203-","A188204-","A188205-","A188206-","T188207-","G188208-","A188209-","T188210-","A188211-","T188212-","G188213-","G188214-","A188215-","A188216-","T188217-","A188218-","C188219-","C188220-","A188221-","T188222-","T188223-","T188224-","G188225-","T188226-","A188227-","A188228-","G188229-","A188230-","A188231-","A188232-","T188233-","G188234-","T188235-","C188236-","G188237-","G188238-","A188239-","A188240-","G188241-","G188242-","G188243-","T188244-","A188245-","C188246-","T188247-","T188248-","A188249-","T188250-","T188251-","C188252-","A188253-","G188254-","A188255-","T188256-","A188257-","T188258-","T188259-","G188260-","T188261-","A188262-","T188263-","C188264-","T188265-","G188266-","A188267-","C188268-","T188269-","C188270-","T188271-","G188272-","A188273-","T188274-","C188275-","A188276-","A188277-","T188278-","G188279-","T188280-","A188281-","A188282-","A188283-","C188284-","C188285-","T188286-","A188287-","T188288-","G188289-","A188290-","C188291-","A188292-","A188293-","G188294-","A188295-","T188296-","A188297-","A188298-","G188299-","A188300-","C188301-","T188302-","T188303-","A188304-","C188305-","T188306-","C188307-","G188308-","C188309-","A188310-","T188311-","C188312-","T188313-","A188314-","C188315-","T188316-","G188317-","G188318-","A188319-","T188320-","A188321-","G188322-","A188323-","C188324-","A188325-","T188326-","A188327-","A188328-","A188329-","T188330-","A188331-","T188332-","C188333-","C188334-","T188335-","C188336-","C188337-","T188338-","C188339-","G188340-","T188341-","A188342-","A188343-","T188344-","A188345-","A188346-","T188347-","G188348-","A188349-","A188350-","A188351-","T188352-","A188353-","T188354-","A188355-","A188356-","T188357-","A188358-","T188359-","A188360-","C188361-","A188362-","C188363-","T188364-","A188365-","A188366-","T188367-","T188368-","A188369-","T188370-","T188371-","A188372-","A188373-","T188374-","A188375-","T188376-","C188377-","A188378-","A188379-","T188380-","C188381-","G188382-","A188383-","G188384-","T188385-","A188386-","T188387-","T188388-","A188389-","A188390-","C188391-","A188392-","T188393-","A188394-","T188395-","A188396-","A188397-","G188398-","T188399-","T188400-","A188401-","T188402-","T188403-","T188404-","T188405-","T188406-","A188407-","A188408-","A188409-","C188410-","C188411-","C188412-","C188413-","T188414-","T188415-","T188416-","T188417-","G188418-","G188419-","G188420-","T188421-","T188422-","C188423-","C188424-","G188425-","T188426-","C188427-","C188428-","T188429-","A188430-","A188431-","A188432-","C188433-","G188434-","G188435-","C188436-","G188437-","T188438-","T188439-","T188440-","C188441-","G188442-","G188443-","T188444-","C188445-","T188446-","G188447-","T188448-","G188449-","T188450-","C188451-","G188452-","C188453-","C188454-","A188455-","C188456-","C188457-","A188458-","T188459-","G188460-","G188461-","T188462-","C188463-","A188464-","C188465-","A188466-","C188467-","C188468-","G188469-","A188470-","G188471-","C188472-","C188473-","T188474-","C188475-","T188476-","G188477-","C188478-","G188479-","T188480-","G188481-","C188482-","T188483-","C188484-","C188485-","T188486-","C188487-","C188488-","A188489-","T188490-","C188491-","G188492-","A188493-","G188494-","G188495-","A188496-","C188497-","G188498-","A188499-","C188500-","T188501-","T188502-","C188503-","A188504-","A188505-","C188506-","T188507-","A188508-","T188509-","G188510-","A188511-","C188512-","A188513-","G188514-","C188515-","T188516-","C188517-","G188518-","G188519-","T188520-","G188521-","G188522-","C188523-","G188524-","T188525-","C188526-","T188527-","G188528-","C188529-","C188530-","A188531-","G188532-","C188533-","G188534-","T188535-","G188536-","T188537-","A188538-","C188539-","A188540-","T188541-","A188542-","C188543-","G188544-","A188545-","A188546-","T188547-","G188548-","G188549-","C188550-","A188551-","T188552-","T188553-","T188554-","C188555-","T188556-","A188557-","A188558-","G188559-","A188560-","A188561-","A188562-","A188563-","G188564-","T188565-","C188566-","T188567-","A188568-","C188569-","G188570-","G188571-","T188572-","A188573-","T188574-","C188575-","C188576-","T188577-","T188578-","T188579-","C188580-","T188581-","A188582-","C188583-","A188584-","A188585-","T188586-","T188587-","T188588-","C188589-","C188590-","T188591-","T188592-","T188593-","A188594-","A188595-","C188596-","A188597-","A188598-","C188599-","G188600-","G188601-","C188602-","A188603-","A188604-","C188605-","A188606-","G188607-","C188608-","T188609-","G188610-","C188611-","A188612-","G188613-","T188614-","A188615-","T188616-","T188617-","T188618-","T188619-","T188620-","A188621-","T188622-","A188623-","C188624-","T188625-","T188626-","T188627-","G188628-","A188629-","A188630-","T188631-","G188632-","C188633-","A188634-","T188635-","C188636-","G188637-","G188638-","A188639-","C188640-","A188641-","T188642-","T188643-","T188644-","A188645-","T188646-","A188647-","C188648-","A188649-","A188650-","G188651-","G188652-","G188653-","A188654-","G188655-","T188656-","C188657-","C188658-","T188659-","G188660-","T188661-","T188662-","C188663-","T188664-","A188665-","A188666-","T188667-","A188668-","T188669-","T188670-","G188671-","G188672-","C188673-","A188674-","T188675-","C188676-","A188677-","A188678-","T188679-","G188680-","T188681-","T188682-","C188683-","G188684-","G188685-","A188686-","T188687-","C188688-","T188689-","A188690-","T188691-","A188692-","G188693-","G188694-","C188695-","T188696-","T188697-","G188698-","A188699-","T188700-","T188701-","T188702-","T188703-","C188704-","G188705-","C188706-","A188707-","T188708-","T188709-","G188710-","A188711-","C188712-","T188713-","T188714-","T188715-","A188716-","C188717-","A188718-","C188719-","A188720-","G188721-","A188722-","C188723-","A188724-","T188725-","G188726-","A188727-","A188728-","C188729-","A188730-","T188731-","C188732-","C188733-","C188734-","C188735-","T188736-","G188737-","A188738-","A188739-","T188740-","C188741-","T188742-","G188743-","T188744-","A188745-","C188746-","A188747-","T188748-","A188749-","C188750-","T188751-","T188752-","T188753-","G188754-","T188755-","G188756-","G188757-","A188758-","T188759-","T188760-","T188761-","A188762-","C188763-","A188764-","C188765-","T188766-","G188767-","T188768-","T188769-","A188770-","G188771-","A188772-","A188773-","T188774-","C188775-","T188776-","C188777-","T188778-","A188779-","A188780-","C188781-","G188782-","C188783-","T188784-","G188785-","G188786-","C188787-","C188788-","T188789-","C188790-","T188791-","G188792-","T188793-","T188794-","G188795-","T188796-","T188797-","A188798-","C188799-","T188800-","T188801-","T188802-","C188803-","T188804-","A188805-","T188806-","G188807-","A188808-","T188809-","G188810-","C188811-","A188812-","C188813-","G188814-","T188815-","A188816-","T188817-","C188818-","G188819-","T188820-","T188821-","A188822-","T188823-","G188824-","C188825-","A188826-","A188827-","G188828-","C188829-","T188830-","T188831-","T188832-","C188833-","A188834-","T188835-","G188836-","T188837-","T188838-","G188839-","A188840-","C188841-","T188842-","A188843-","C188844-","T188845-","G188846-","C188847-","A188848-","G188849-","T188850-","G188851-","T188852-","T188853-","T188854-","C188855-","T188856-","T188857-","G188858-","C188859-","T188860-","C188861-","T188862-","G188863-","A188864-","C188865-","T188866-","A188867-","C188868-","A188869-","T188870-","A188871-","T188872-","A188873-","C188874-","T188875-","C188876-","T188877-","A188878-","C188879-","A188880-","A188881-","T188882-","C188883-","A188884-","A188885-","A188886-","G188887-","A188888-","A188890-","G188891-","A188892-","T188893-","T188894-","T188895-","C188896-","A188897-","G188898-","T188899-","A188900-","A188901-","A188902-","C188903-","T188904-","T188905-","G188906-","T188907-","A188908-","A188909-","C188910-","A188911-","G188912-","G188913-","A188914-","T188915-","T188916-","G188917-","T188918-","T188919-","T188920-","G188921-","C188922-","T188923-","G188924-","C188925-","T188926-","T188927-","T188928-","C188929-","T188930-","G188931-","G188932-","A188933-","T188934-","T188935-","T188936-","T188937-","A188938-","A188939-","T188940-","T188941-","T188942-","T188943-","G188944-","T188945-","C188946-","A188947-","G188948-","G188949-","A188950-","G188951-","T188952-","C188953-","T188954-","T188955-","G188956-","A188957-","G188958-","G188959-","A188960-","T188961-","A188962-","A188963-","A188964-","G188965-","T188966-","T188967-","T188968-","A188969-","A188970-","A188971-","A188972-","T188973-","A188974-","G188975-","A188976-","A188977-","T188978-","T188979-","A188980-","A188981-","T188982-","A188983-","A188984-","A188985-","G188986-","A188987-","A188988-","C188989-","A188990-","T188991-","A188992-","T188993-","A188994-","G188995-","G188996-","T188997-","C188998-","A188999-","T189000-","T189001-","T189002-","T189003-","T189004-","T189005-","A189006-","A189007-","A189008-","C189009-","A189010-","T189011-","G189012-","G189013-","A189014-","T189015-","A189016-","G189017-","A189018-","A189019-","A189020-","C189021-","C189022-","A189023-","A189024-","G189025-","T190132-","A190133-","T190134-","T190135-","A190136-","A190137-","T190138-","G190139-","G190140-","A190141-","T190142-","A190143-","T190144-","A190145-","T190146-","A190147-","G190148-","A190149-","T190150-","A190151-","A190152-","C190153-","G190154-","C190155-","A190156-","A190157-","T190158-","A190159-","G190160-","G190161-","G190162-","A190163-","C190164-","T190165-","A190166-","A190167-","T190168-","A190169-","G190170-","T190171-","A190172-","T190173-","T190174-","G190175-","T190176-","A190177-","A190178-","A190179-","A190180-","G190181-","A190182-","T190183-","A190184-","T190185-","G190345A"],"OPG071":["R246Q"],"OPG192":["T46-","D47-","D48-","N49-","N50-","E51-","L52-","V53-","L54-","N55-","F56-","K57-","E58-","Y59-","T60-","I61-","S62-","I63-","I64-","T65-","E66-","S67-","C68-","D69-","V70-","G71-","F72-","D73-","S74-","I75-","D76-","I77-","D78-","V79-","I80-","N81-","D82-","Y83-","K84-","I85-","I86-","D87-","M88-","Y89-","T90-"],"OPG195":["T118N","L119-","C120-","I121-","S122-","V123-","Y124-","C125-","D126-","Q127-","E128-","A129-","G130-","D131-","I172-","L210-","K211-","S212-","K213-","A214-","L215-","H216-"]},"labels":{"aa":"OPG071: R246Q; OPG192: T46-, D47-, D48-, N49-, N50-, E51-, L52-, V53-, L54-, N55-, F56-, K57-, E58-, Y59-, T60-, I61-, S62-, I63-, I64-, T65-, E66-, S67-, C68-, D69-, V70-, G71-, F72-, D73-, S74-, I75-, D76-, I77-, D78-, V79-, I80-, N81-, D82-, Y83-, K84-, I85-, I86-, D87-, M88-, Y89-, T90-; OPG195: T118N, L119-, C120-, I121-, S122-, V123-, Y124-, C125-, D126-, Q127-, E128-, A129-, G130-, D131-, I172-, L210-, K211-, S212-, K213-, A214-, L215-, H216-"}}},{"name":"NODE_0000023","node_attrs":{"div":19,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["C23353T","C51809T","G69678A","C125492T","C128174T","-188889A"],"OPG039":["D256N"],"OPG071":["R877Q"],"OPG146":["D50N"]},"labels":{"aa":"OPG039: D256N; OPG071: R877Q; OPG146: D50N"}},"children":[{"name":"NODE_0000024","node_attrs":{"div":20,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["T27971C","A146894-","A146896-","A146901-","A146906-","A146908-","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","-173314A","-173315T","-173316A","-173317T"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}},"children":[{"name":"MK783033","node_attrs":{"div":30,"accession":"MK783033","author":{"author":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J.","value":"Yinka-Ogunleye,A.,Aruna,O.,Dalhat,M.,Ogoina,D.,McCollum,A.,Disu,Y.,Mamadu,I.,Akinpelu,A.,Ahmad,A.,Burga,J.,Ndoreraho,A.,Nkunzimana,E.,Manneh,L.,Mohammed,A.,Adeoye,O.,Tom-Aba,D.,Silenou,B.,Ipadeola,O.,Saleh,M.,Adeyemo,A.,Nwadiutor,I.,Aworabhi,N.,Uke,P.,John,D.,Wakama,P.,Reynolds,M.,Mauldin,M.,Doty,J.,Wilkins,K.,Musa,J.,Khalakdina,A.,Adedeji,A.,Mba,N.,Ojo,O.,Krause,G.,Ihekweazu,C.,Mauldin,M.R.,Li,Y.,Gao,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, NCEZID/DHCPP/PRB"},"lineage":{"value":"A.3"},"strain":{"value":"MK783033"},"date":{"value":"2017-10-09"},"strain_display":{"value":"Nigeria/MK783033/2017-10-09"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-608T","C25731T","C25768T","C26020T","A56968G","G102267T","C117099T","G129583A","C155707T","G161701A","T187428C"],"OPG042":["D360N"],"OPG074":["L53S"],"OPG121":["G160C"],"OPG136":["R830Q"],"OPG188":["V36I"]},"labels":{"aa":"OPG042: D360N; OPG074: L53S; OPG121: G160C; OPG136: R830Q; OPG188: V36I"}}},{"name":"OP535335","node_attrs":{"div":20,"accession":"OP535335","author":{"author":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y.","value":"Nnaemeka,N.,Akanbi,O.,Chukwu,C.,Ayansola,O.,Ahmad,A.,Yinka-Ogunleye,A.,Akinpelu,A.,Babatunde,O.,Ihekweazu,C.,Adetifa,I.,Mauldin,M.R.,Gigante,C.M.,Batra,D.,Weigand,M.R.,Howard,D.T.,Sheth,M.,Seabolt,M.H.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Nigeria Centre for Disease Control, National Reference Laboratory"},"lineage":{"value":"A.3"},"strain":{"value":"MPXV_Nigeria_2017_2947"},"date":{"value":"2017-10-XX"},"strain_display":{"value":"Nigeria/OP535335/2017-10-XX"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000025","node_attrs":{"div":24,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["T607-","C92053T","C123000T","C146052T","-146895T","-146897T","-146898T","-146899T","-146900T","-146902T","-146903T","-146904T","-146905T","-146907T","-146909T","-146910T","-146911T","-146912T","C150831T","C151305T"],"OPG113":["S108L"],"OPG143":["E106K"]},"labels":{"aa":"OPG113: S108L; OPG143: E106K"}},"children":[{"name":"OP612677","node_attrs":{"div":27,"accession":"OP612677","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.3"},"strain":{"value":"MPXV/015/19"},"date":{"value":"2019-03-12"},"strain_display":{"value":"Nigeria/OP612677/2019-03-12"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C56351T","G74032A","T76087-","A89106-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","G190782A"],"OPG016":["E125K"],"OPG074":["E259K"],"OPG094":["A85T"]},"labels":{"aa":"OPG016: E125K; OPG074: E259K; OPG094: A85T"}}},{"name":"NODE_0000026","node_attrs":{"div":53,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.3"}},"branch_attrs":{"mutations":{"nuc":["T606-","C2930T","C18493T","C18908T","G21898A","G23626A","C25254T","C29199T","G36901A","G44085A","G63034A","G75099A","G75144A","G76509A","C87659T","G115332A","C115572T","G122627A","C128771T","C140739T","A149394-","G151519T","G151875A","C160008T","C160312T","G165130A","G168862A","-173314A","-173315T","-173316A","-173317T","G174491A","G176289A","G176366A","C177703T","G194280A","A196614-","A196615-"],"OPG003":["E560K"],"OPG003_dup":["E560K"],"OPG037":["S179L"],"OPG039":["H165Y"],"OPG045":["E22K"],"OPG064":["S605L"],"OPG082":["S140L"],"OPG097":["H123Y"],"OPG109":["E597K"],"OPG133":["R42Q","S122F"],"OPG143":["T230M"],"OPG178":["G4V","D123N"],"OPG205":["A212T","M237I","S683L"]},"labels":{"aa":"OPG003: E560K; OPG003_dup: E560K; OPG037: S179L; OPG039: H165Y; OPG045: E22K; OPG064: S605L; OPG082: S140L; OPG097: H123Y; OPG109: E597K; OPG133: R42Q, S122F; OPG143: T230M; OPG178: G4V, D123N; OPG205: A212T, M237I, S683L"}},"children":[{"name":"OP413718","node_attrs":{"div":53,"accession":"OP413718","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"A.3"},"strain":{"value":"9000360"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP413718/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133171-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"]}}},{"name":"OP536812","node_attrs":{"div":53,"accession":"OP536812","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"A.3"},"strain":{"value":"9000450"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536812/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000027","node_attrs":{"div":18,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["C23564T","C72362T","C83326T","G87230A","G87297A","G91728A","C119296T","C121320T","G125249A","-146895T","-146897T","-146898T","-146899T","-146900T","-146902T","-146903T","-146904T","-146905T","-146907T","-146909T","-146910T","-146911T","-146912T","G148412A","C164832T","C168120T"],"OPG092":["D196N"],"OPG105":["S734L"],"OPG109":["H740Y"],"OPG136":["D98N"],"OPG139":["A17T"],"OPG145":["E435K"],"OPG193":["L263F"]},"labels":{"aa":"OPG092: D196N; OPG105: S734L; OPG109: H740Y; OPG136: D98N; OPG139: A17T; OPG145: E435K; OPG193: L263F","clade":"A.1"}},"children":[{"name":"MT903343","node_attrs":{"div":21,"accession":"MT903343","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-UK_P1"},"date":{"value":"2018-09-XX"},"strain_display":{"value":"United Kingdom/MT903343/2018-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-608T","G28838A","G92349A","-173314A","-173315T","-173316A","-173317T","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","G188494A","-196616A"],"OPG045":["A142V"],"OPG113":["E207K"]},"labels":{"aa":"OPG045: A142V; OPG113: E207K"}}},{"name":"MN648051","node_attrs":{"div":22,"accession":"MN648051","author":{"author":"Cohen Gihon,I.,Israeli,O.,Shifman,O.,Erez,N.,Melamed,S.,Paran,N.,Beth-Din,A.,Zvi,A.","value":"Cohen Gihon,I.,Israeli,O.,Shifman,O.,Erez,N.,Melamed,S.,Paran,N.,Beth-Din,A.,Zvi,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Israel"},"clade_membership":{"value":"IIb"},"institution":{"value":"Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel"},"lineage":{"value":"A.1"},"strain":{"value":"MN648051"},"date":{"value":"2018-10-04"},"strain_display":{"value":"Israel/MN648051/2018-10-04"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T607-","C8772T","C91363T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A147593T","G150568A","G177273A","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A196615-"],"OPG172":["E56V"],"OPG205":["D540N"]},"labels":{"aa":"OPG172: E56V; OPG205: D540N"}}},{"name":"MT903341","node_attrs":{"div":20,"accession":"MT903341","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-M5320_M15_Bayelsa"},"date":{"value":"2018-08-14"},"strain_display":{"value":"Nigeria/MT903341/2018-08-14"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-608T","G3153-","A3154-","T3155-","T3156-","C3157-","G3158-","A3159-","A3160-","T3161-","C3162-","T3163-","C3164-","T3165-","T3166-","T3167-","G3168-","A3169-","G3170-","G3171-","A3172-","G3173-","A3174-","C3175-","T3176-","T3177-","A3178-","T3179-","G3180-","T3181-","C3182-","A3183-","C3184-","G3185-","A3186-","C3187-","T3188-","A3189-","C3190-","A3191-","T3192-","T3193-","T3194-","T3195-","T3196-","C3197-","G3198-","A3199-","T3200-","G3201-","A3202-","T3203-","G3204-","G3205-","A3206-","A3207-","T3208-","C3209-","T3210-","A3211-","T3212-","C3213-","T3214-","T3215-","A3216-","T3217-","C3218-","G3219-","A3220-","A3221-","T3222-","G3223-","A3224-","T3225-","A3226-","T3227-","A3228-","T3229-","T3230-","T3231-","T3232-","T3233-","C3234-","A3235-","T3236-","A3237-","A3238-","A3239-","T3240-","A3241-","C3242-","A3243-","C3244-","T3245-","T3246-","T3247-","T3248-","A3249-","T3250-","A3251-","G3252-","T3253-","C3254-","C3255-","T3256-","C3257-","G3258-","T3259-","T3260-","T3261-","A3262-","A3263-","A3264-","C3265-","A3266-","G3267-","A3268-","A3269-","T3270-","T3271-","T3272-","A3273-","G3274-","T3275-","A3276-","T3277-","G3278-","T3279-","A3280-","G3281-","T3282-","T3283-","C3284-","C3285-","G3286-","C3287-","A3288-","A3289-","A3290-","T3291-","G3292-","A3293-","C3294-","T3295-","C3296-","G3297-","T3298-","C3299-","C3300-","C3301-","T3302-","T3303-","A3304-","A3305-","T3306-","A3307-","G3308-","G3309-","C3310-","A3311-","G3312-","T3313-","A3314-","G3315-","G3316-","C3317-","T3318-","A3319-","T3320-","T3321-","A3322-","T3323-","C3324-","T3325-","T3326-","C3327-","T3328-","T3329-","T3330-","A3331-","C3332-","G3333-","T3334-","A3335-","G3336-","T3337-","G3338-","A3339-","T3340-","C3341-","G3342-","T3343-","C3344-","G3345-","T3346-","A3347-","G3348-","G3349-","G3350-","A3351-","G3352-","A3353-","G3354-","A3355-","A3356-","C3357-","T3358-","C3359-","C3360-","G3361-","A3362-","C3363-","A3364-","T3365-","C3366-","T3367-","T3368-","G3369-","T3370-","A3371-","G3372-","A3373-","A3374-","C3375-","A3376-","A3377-","C3378-","G3379-","A3380-","T3381-","T3382-","T3383-","A3384-","A3385-","T3386-","C3387-","A3388-","T3389-","A3390-","G3391-","G3392-","T3393-","A3394-","G3395-","A3396-","G3397-","A3398-","T3399-","A3400-","C3401-","T3402-","T3403-","T3404-","C3405-","A3406-","G3407-","T3408-","C3409-","T3410-","G3411-","T3412-","G3413-","G3414-","T3415-","G3416-","G3417-","A3418-","T3419-","A3420-","A3421-","T3422-","G3423-","T3424-","C3425-","A3426-","T3427-","T3428-","A3429-","A3430-","C3431-","G3432-","A3433-","C3434-","A3435-","T3436-","C3437-","C3438-","G3439-","C3440-","C3441-","T3442-","T3443-","G3444-","T3445-","A3446-","T3447-","A3448-","T3449-","A3450-","A3451-","T3452-","G3453-","T3454-","T3455-","T3456-","C3457-","T3458-","G3459-","T3460-","T3461-","T3462-","T3463-","C3464-","A3465-","A3466-","A3467-","C3468-","A3469-","C3470-","C3471-","A3472-","A3473-","G3474-","T3475-","C3476-","G3477-","A3478-","A3479-","T3480-","A3481-","C3482-","T3483-","G3484-","T3485-","C3486-","T3487-","T3488-","A3489-","T3490-","C3491-","G3492-","T3493-","C3494-","T3495-","T3496-","T3497-","A3498-","G3499-","T3500-","C3501-","G3502-","G3503-","A3504-","A3505-","G3506-","G3507-","T3508-","T3509-","G3510-","A3511-","T3512-","G3513-","T3514-","C3515-","G3516-","T3517-","A3518-","T3519-","C3520-","C3521-","G3522-","A3523-","T3524-","G3525-","T3526-","A3527-","T3528-","A3529-","C3530-","G3531-","A3532-","G3533-","G3534-","T3535-","A3536-","T3537-","G3538-","A3539-","G3540-","G3541-","C3542-","A3543-","A3544-","C3545-","A3546-","T3547-","T3548-","G3549-","T3550-","T3551-","A3552-","T3553-","T3554-","G3555-","C3556-","A3557-","A3558-","T3559-","T3560-","C3561-","T3562-","G3563-","G3564-","A3565-","A3566-","G3567-","G3568-","C3569-","G3570-","G3571-","T3572-","A3573-","T3574-","G3575-","A3576-","A3577-","G3578-","A3579-","G3580-","G3581-","A3582-","G3583-","T3584-","C3585-","A3586-","T3587-","T3588-","G3589-","T3590-","A3591-","T3592-","T3593-","A3594-","T3595-","A3596-","G3597-","T3598-","A3599-","T3600-","T3601-","C3602-","G3603-","T3604-","C3605-","T3606-","T3607-","T3608-","C3609-","T3610-","G3611-","A3612-","A3613-","T3614-","G3615-","T3616-","C3617-","G3618-","A3619-","A3620-","T3621-","C3622-","T3623-","A3624-","T3625-","C3626-","T3627-","A3628-","G3629-","T3630-","A3631-","G3632-","A3633-","T3634-","A3635-","C3636-","C3637-","G3638-","T3639-","A3640-","G3641-","T3642-","A3643-","T3644-","A3645-","T3646-","T3647-","G3648-","A3649-","G3650-","A3651-","G3652-","A3653-","G3654-","C3655-","G3656-","A3657-","C3658-","T3659-","T3660-","C3661-","C3662-","A3663-","T3664-","A3665-","T3666-","C3667-","C3668-","T3669-","T3670-","G3671-","A3672-","T3673-","T3674-","A3675-","T3676-","G3677-","T3678-","T3679-","T3680-","T3681-","A3682-","T3683-","G3684-","A3685-","A3686-","T3687-","A3688-","G3689-","A3690-","T3691-","A3692-","A3693-","A3694-","G3695-","T3696-","A3697-","G3698-","A3699-","T3700-","G3701-","T3702-","T3703-","G3704-","T3705-","C3706-","C3707-","T3708-","T3709-","C3710-","T3711-","T3712-","C3713-","C3714-","T3715-","T3716-","T3717-","T3718-","G3719-","T3720-","A3721-","A3722-","T3723-","T3724-","T3725-","C3726-","C3727-","C3728-","G3729-","T3730-","A3731-","T3732-","T3733-","T3734-","T3735-","T3736-","G3737-","T3738-","T3739-","C3740-","G3741-","T3742-","G3743-","C3744-","C3745-","A3746-","A3747-","T3748-","T3749-","G3750-","A3751-","G3752-","T3753-","A3754-","A3755-","C3756-","A3757-","T3758-","T3759-","A3760-","T3761-","G3762-","A3763-","G3764-","A3765-","A3766-","T3767-","A3768-","T3769-","G3770-","A3771-","C3772-","C3773-","T3774-","G3775-","T3776-","T3777-","G3778-","C3779-","A3780-","C3781-","A3782-","A3783-","T3784-","C3785-","G3786-","T3787-","T3788-","C3789-","T3790-","T3791-","T3792-","A3793-","T3794-","G3795-","T3796-","A3797-","T3798-","T3799-","C3800-","C3801-","A3802-","T3803-","G3804-","A3805-","T3806-","G3807-","G3808-","G3809-","T3810-","G3811-","T3812-","A3813-","C3814-","A3815-","A3816-","T3817-","C3818-","A3819-","A3820-","G3821-","A3822-","T3823-","T3824-","A3825-","T3826-","T3827-","A3828-","C3829-","G3830-","T3831-","A3832-","T3833-","C3834-","C3835-","T3836-","C3837-","G3838-","T3839-","A3840-","T3841-","C3842-","G3843-","G3844-","C3845-","T3846-","C3847-","C3848-","T3849-","C3850-","G3851-","A3852-","G3853-","A3854-","T3855-","A3856-","A3857-","A3858-","A3859-","G3860-","A3861-","G3862-","C3863-","A3864-","T3865-","A3866-","C3867-","A3868-","C3869-","C3870-","A3871-","C3872-","A3873-","C3874-","G3875-","A3876-","G3877-","G3878-","A3879-","C3880-","T3881-","A3882-","T3883-","G3884-","T3885-","T3886-","T3887-","G3888-","G3889-","T3890-","A3891-","T3892-","A3893-","C3894-","T3895-","G3896-","T3897-","T3898-","G3899-","A3900-","A3901-","G3902-","G3903-","T3904-","A3905-","A3906-","G3907-","T3908-","G3909-","T3910-","G3911-","T3912-","A3913-","A3914-","C3915-","G3916-","G3917-","C3918-","G3919-","T3920-","A3921-","T3922-","T3923-","T3924-","C3925-","C3926-","G3927-","A3928-","T3929-","T3930-","T3931-","T3932-","C3933-","G3934-","T3935-","A3936-","A3937-","C3938-","C3939-","G3940-","C3941-","G3942-","T3943-","T3944-","A3945-","A3946-","T3947-","G3948-","T3949-","T3950-","T3951-","G3952-","C3953-","T3954-","C3955-","C3956-","A3957-","T3958-","G3959-","A3960-","T3961-","C3962-","T3963-","A3964-","T3965-","T3966-","A3967-","T3968-","C3969-","G3970-","C3971-","G3972-","T3973-","A3974-","G3975-","A3976-","T3977-","G3978-","A3979-","A3980-","T3981-","C3982-","G3983-","C3984-","T3985-","T3986-","C3987-","T3988-","C3989-","A3990-","G3991-","C3992-","T3993-","C3994-","G3995-","C3996-","A3997-","T3998-","C3999-","T4000-","T4001-","A4002-","G4003-","T4004-","G4005-","T4006-","G4007-","A4008-","C4009-","T4010-","C4011-","T4012-","T4013-","T4014-","G4015-","A4016-","C4017-","T4018-","T4019-","G4020-","T4021-","A4022-","A4023-","T4024-","A4025-","A4026-","T4027-","T4028-","G4029-","C4030-","T4031-","T4032-","T4033-","C4034-","G4035-","T4036-","G4037-","G4038-","A4039-","A4040-","C4041-","G4042-","C4043-","G4044-","G4045-","A4046-","T4047-","A4048-","T4049-","G4050-","T4051-","G4052-","T4053-","T4054-","T4055-","A4056-","C4057-","A4058-","G4059-","T4060-","A4061-","G4062-","T4063-","A4064-","A4065-","T4066-","G4067-","A4068-","A4069-","G4070-","A4071-","G4072-","A4073-","A4074-","G4075-","T4076-","G4077-","A4078-","G4079-","T4080-","C4081-","C4082-","A4083-","T4084-","C4085-","C4086-","T4087-","C4088-","A4089-","T4090-","C4091-","G4092-","A4093-","C4094-","G4095-","C4096-","A4097-","A4098-","T4099-","T4100-","A4101-","G4102-","G4103-","G4104-","T4105-","C4106-","A4107-","G4108-","A4109-","T4110-","C4111-","C4112-","T4113-","T4114-","T4115-","A4116-","G4117-","T4118-","C4119-","A4120-","A4121-","T4122-","A4123-","A4124-","T4125-","T4126-","T4127-","G4128-","T4129-","A4130-","C4131-","A4132-","G4133-","A4134-","A4135-","C4136-","G4137-","T4138-","A4139-","A4140-","T4141-","A4142-","G4143-","T4144-","T4145-","T4146-","A4147-","A4148-","G4149-","C4150-","T4151-","C4152-","C4153-","C4154-","A4155-","T4156-","T4157-","G4158-","A4159-","A4160-","T4161-","T4162-","T4163-","A4164-","T4165-","A4166-","T4167-","C4168-","T4169-","A4170-","A4171-","G4172-","A4173-","T4174-","A4175-","A4176-","C4177-","A4178-","C4179-","A4180-","G4181-","C4182-","A4183-","A4184-","T4185-","A4186-","G4187-","A4188-","T4189-","C4190-","G4191-","G4192-","A4193-","T4194-","G4195-","A4196-","T4197-","T4198-","T4199-","A4200-","C4201-","T4202-","A4203-","A4204-","A4205-","G4206-","T4207-","C4208-","A4209-","T4210-","C4211-","A4212-","A4213-","T4214-","G4215-","G4216-","G4217-","G4218-","T4219-","C4220-","C4221-","G4222-","T4223-","T4224-","A4225-","G4226-","T4227-","A4228-","T4229-","A4230-","T4231-","C4232-","A4233-","A4234-","A4235-","G4236-","A4237-","T4238-","C4239-","T4240-","T4241-","G4242-","T4243-","T4244-","A4245-","T4246-","C4247-","G4248-","A4249-","T4250-","T4251-","G4252-","A4253-","T4254-","A4255-","G4256-","T4257-","G4258-","A4259-","A4260-","T4261-","G4262-","A4263-","A4264-","T4265-","C4266-","A4267-","G4268-","A4269-","T4270-","A4271-","G4272-","T4273-","G4274-","G4275-","T4276-","G4277-","T4278-","A4279-","G4280-","A4281-","G4282-","G4283-","A4284-","A4285-","T4286-","A4287-","T4288-","G4289-","T4290-","C4291-","C4292-","T4293-","T4294-","T4295-","T4296-","T4297-","T4298-","A4299-","T4300-","C4301-","C4302-","T4303-","T4304-","G4305-","C4306-","T4307-","A4308-","T4309-","C4310-","A4311-","A4312-","A4313-","G4314-","T4315-","T4316-","A4317-","C4318-","G4319-","C4320-","A4321-","T4322-","G4323-","C4324-","C4325-","G4326-","T4327-","G4328-","G4329-","C4330-","G4331-","T4332-","A4333-","A4334-","C4335-","A4336-","A4337-","T4338-","A4339-","T4340-","C4341-","T4342-","T4343-","T4344-","A4345-","A4346-","T4347-","A4348-","C4349-","A4350-","G4351-","A4352-","T4353-","G4354-","G4355-","A4356-","T4357-","T4358-","A4359-","A4360-","A4361-","T4362-","C4363-","G4364-","T4365-","G4366-","T4367-","A4368-","T4369-","T4370-","C4371-","A4372-","T4373-","C4374-","G4375-","T4376-","A4377-","T4378-","A4379-","G4380-","C4381-","A4382-","A4383-","T4384-","G4385-","T4386-","A4387-","A4388-","T4389-","G4390-","G4391-","A4392-","G4393-","A4394-","G4395-","T4396-","T4397-","A4398-","C4399-","C4400-","A4401-","C4402-","A4403-","T4404-","T4405-","T4406-","T4407-","A4408-","G4409-","T4410-","C4411-","G4412-","T4413-","T4414-","T4415-","A4416-","T4417-","T4418-","C4419-","A4420-","G4421-","A4422-","T4423-","C4424-","G4425-","C4426-","A4427-","G4428-","T4429-","G4430-","T4431-","T4432-","T4433-","A4434-","A4435-","T4436-","A4437-","A4438-","C4439-","T4440-","A4441-","A4442-","T4443-","T4444-","T4445-","A4446-","A4447-","A4448-","C4449-","A4450-","G4451-","A4452-","T4453-","G4454-","A4455-","G4456-","A4457-","T4458-","G4459-","A4460-","T4461-","A4462-","T4463-","A4464-","T4465-","C4466-","C4467-","A4468-","C4469-","A4470-","T4471-","C4472-","A4473-","A4474-","A4475-","G4476-","A4477-","A4478-","T4479-","G4480-","C4481-","G4482-","A4483-","G4484-","A4485-","T4486-","A4487-","C4488-","A4489-","T4490-","A4491-","T4492-","G4493-","A4494-","C4495-","A4496-","G4497-","A4498-","C4499-","A4500-","T4501-","T4502-","A4503-","T4504-","T4505-","G4506-","A4507-","C4508-","A4509-","G4510-","A4511-","A4512-","A4513-","T4514-","G4515-","T4516-","G4517-","A4518-","C4519-","C4520-","T4521-","T4522-","C4523-","A4524-","T4525-","T4526-","A4527-","T4528-","C4529-","A4530-","C4531-","C4532-","G4533-","T4534-","C4535-","G4536-","T4537-","C4538-","C4539-","A4540-","T4541-","A4542-","A4543-","A4544-","T4545-","G4546-","C4547-","G4548-","T4549-","T4550-","A4551-","G4552-","G4553-","T4554-","A4555-","C4556-","G4557-","T4558-","A4559-","C4560-","C4561-","A4562-","C4563-","A4564-","T4565-","A4566-","C4567-","T4568-","A4569-","T4570-","C4571-","G4572-","T4573-","T4574-","A4575-","A4576-","C4577-","G4578-","A4579-","T4580-","G4581-","C4582-","G4583-","C4584-","A4585-","C4586-","A4587-","A4588-","T4589-","C4590-","T4591-","C4592-","G4593-","T4594-","C4595-","C4596-","A4597-","T4598-","T4599-","T4600-","C4601-","A4602-","T4603-","C4604-","C4605-","A4606-","T4607-","C4608-","T4609-","T4610-","C4611-","A4612-","T4613-","A4614-","A4615-","T4616-","G4617-","A4618-","T4619-","T4620-","T4621-","A4622-","C4623-","T4624-","T4625-","T4626-","T4627-","T4628-","C4629-","A4630-","T4631-","A4632-","A4633-","T4634-","T4635-","A4636-","G4637-","A4638-","G4639-","A4640-","A4641-","A4642-","A4643-","A4644-","G4645-","A4646-","T4647-","C4648-","A4649-","A4650-","G4651-","G4652-","T4653-","A4654-","T4655-","A4656-","A4657-","A4658-","A4659-","A4660-","T4661-","T4662-","A4663-","G4664-","A4665-","A4666-","G4667-","T4668-","G4669-","T4670-","T4671-","A4672-","G4673-","A4674-","C4675-","T4676-","A4677-","T4678-","A4679-","A4680-","A4681-","C4682-","T4683-","A4684-","A4685-","C4686-","T4687-","T4688-","A4689-","T4690-","G4691-","A4692-","C4693-","T4694-","T4695-","A4696-","A4697-","C4698-","T4699-","A4700-","A4701-","C4702-","T4703-","T4704-","A4705-","T4706-","G4707-","A4708-","C4709-","T4710-","T4711-","A4712-","A4713-","C4714-","T4715-","A4716-","A4717-","C4718-","T4719-","T4720-","A4721-","T4722-","G4723-","A4724-","C4725-","T4726-","T4727-","A4728-","A4729-","C4730-","T4731-","A4732-","A4733-","C4734-","T4735-","T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","A4748-","A4749-","C4750-","T4751-","T4752-","A4753-","T4754-","G4755-","A4756-","C4757-","T4758-","T4759-","A4760-","A4761-","C4762-","T4763-","A4764-","A4765-","C4766-","T4767-","T4768-","A4769-","T4770-","G4771-","A4772-","C4773-","T4774-","T4775-","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","A4807-","T4808-","T4809-","A4810-","A4811-","C4812-","T4813-","C4814-","A4815-","T4816-","T4817-","T4818-","C4819-","A4820-","A4821-","G4822-","A4823-","A4824-","A4825-","G4826-","G4827-","T4828-","G4829-","G4830-","G4831-","T4832-","G4833-","G4834-","A4835-","T4836-","A4837-","G4838-","A4839-","A4840-","C4841-","T4842-","C4843-","T4844-","A4845-","T4846-","A4847-","T4848-","G4849-","A4850-","C4851-","A4852-","G4853-","C4854-","T4855-","T4856-","G4857-","T4858-","G4859-","A4860-","A4861-","A4862-","C4863-","A4864-","A4865-","T4866-","T4867-","A4868-","G4869-","A4870-","T4871-","C4872-","C4873-","C4874-","T4875-","A4876-","A4877-","T4878-","T4879-","T4880-","C4881-","T4882-","A4883-","A4884-","T4885-","G4886-","G4887-","A4888-","A4889-","G4890-","T4891-","T4892-","T4893-","T4894-","G4895-","A4896-","T4897-","A4898-","G4899-","G4900-","A4901-","G4902-","A4903-","T4904-","T4905-","G4906-","T4907-","C4908-","A4909-","T4910-","C4911-","A4912-","G4913-","T4914-","T4915-","G4916-","A4917-","T4918-","A4919-","C4920-","A4921-","T4922-","T4923-","G4924-","T4925-","T4926-","T4927-","A4928-","T4929-","T4930-","A4931-","T4932-","C4933-","T4934-","C4935-","A4936-","T4937-","C4938-","T4939-","A4940-","T4941-","T4942-","A4943-","G4944-","A4945-","G4946-","C4947-","A4948-","C4949-","G4950-","T4951-","C4952-","T4953-","G4954-","T4955-","T4956-","T4957-","A4958-","G4959-","A4960-","G4961-","C4962-","T4963-","T4964-","T4965-","A4966-","G4967-","T4968-","G4969-","A4970-","C4971-","C4972-","T4973-","G4974-","C4975-","T4976-","C4977-","G4978-","G4979-","T4980-","T4981-","A4982-","C4983-","T4984-","T4985-","C4986-","T4987-","G4988-","T4989-","G4990-","T4991-","A4992-","A4993-","A4994-","T4995-","C4996-","T4997-","T4998-","G4999-","A5000-","A5001-","T5002-","C5003-","C5004-","T5005-","T5006-","T5007-","A5008-","G5009-","T5010-","G5011-","A5012-","T5013-","A5014-","C5015-","A5016-","C5017-","T5018-","G5019-","T5020-","G5021-","T5022-","C5023-","A5024-","A5025-","A5026-","A5027-","C5028-","T5029-","G5030-","G5031-","A5032-","T5033-","G5034-","T5035-","T5036-","T5037-","A5038-","G5039-","A5040-","A5041-","T5042-","A5043-","C5044-","C5045-","T5046-","A5047-","T5048-","G5049-","T5050-","A5051-","G5052-","A5053-","A5054-","T5055-","A5056-","T5057-","G5058-","G5059-","G5060-","A5061-","A5062-","G5063-","C5064-","A5065-","T5066-","G5067-","C5068-","T5069-","T5070-","G5071-","T5072-","T5073-","T5074-","T5075-","T5076-","G5077-","T5078-","C5079-","T5080-","C5081-","T5082-","A5083-","T5084-","T5085-","A5086-","T5087-","A5088-","G5089-","A5090-","T5091-","T5092-","A5093-","A5094-","C5095-","T5096-","C5097-","A5098-","T5099-","A5100-","C5101-","A5102-","T5103-","G5104-","G5105-","T5106-","T5107-","G5108-","T5109-","A5110-","T5111-","T5112-","A5113-","T5114-","G5115-","A5116-","A5117-","T5118-","T5119-","T5120-","T5121-","C5122-","A5123-","T5124-","C5125-","T5126-","G5127-","C5128-","C5129-","T5130-","A5131-","A5132-","T5133-","G5134-","T5135-","A5136-","C5137-","T5138-","C5139-","C5140-","A5141-","A5142-","T5143-","T5144-","C5145-","T5146-","T5147-","G5148-","T5149-","T5150-","T5151-","A5152-","C5153-","A5154-","A5155-","T5156-","C5157-","A5158-","A5159-","T5160-","T5161-","A5162-","T5163-","A5164-","T5165-","A5166-","A5167-","T5168-","C5169-","A5170-","A5171-","A5172-","G5173-","A5174-","G5175-","T5176-","G5177-","A5178-","T5179-","G5180-","A5181-","T5182-","G5183-","C5184-","A5185-","T5186-","A5187-","C5188-","A5189-","C5190-","A5191-","T5192-","T5193-","A5194-","C5195-","A5196-","A5197-","A5198-","G5199-","T5200-","G5201-","A5202-","A5203-","T5204-","A5205-","A5206-","T5207-","C5208-","T5209-","A5210-","C5211-","C5212-","A5213-","T5214-","C5215-","A5216-","T5217-","A5218-","A5219-","A5220-","A5221-","T5222-","A5223-","C5224-","T5225-","T5226-","G5227-","A5228-","T5229-","A5230-","C5231-","A5232-","G5233-","A5234-","G5235-","C5236-","T5237-","T5238-","T5239-","A5240-","T5241-","C5242-","A5243-","C5244-","A5245-","T5246-","C5247-","A5248-","T5249-","G5250-","G5251-","T5252-","T5253-","T5254-","T5255-","C5256-","A5257-","A5258-","T5259-","T5260-","G5261-","T5262-","A5263-","T5264-","T5265-","A5266-","T5267-","T5268-","A5269-","A5270-","G5271-","T5272-","A5273-","T5274-","A5275-","G5276-","C5277-","T5278-","A5279-","A5280-","T5281-","T5282-","T5283-","T5284-","A5285-","T5286-","A5287-","C5288-","A5289-","G5290-","T5291-","C5292-","A5293-","A5294-","T5295-","A5296-","G5297-","A5298-","C5299-","A5300-","A5301-","T5302-","G5303-","G5304-","T5305-","T5306-","C5307-","T5308-","C5309-","T5310-","A5311-","A5312-","G5313-","C5314-","A5315-","A5316-","T5317-","A5318-","T5319-","T5320-","T5321-","C5322-","T5323-","A5324-","A5325-","T5326-","A5327-","T5328-","T5329-","T5330-","T5331-","A5332-","A5333-","G5334-","A5335-","T5336-","G5337-","T5338-","G5339-","C5340-","T5341-","T5342-","C5343-","C5344-","C5345-","T5346-","A5347-","C5348-","G5349-","G5350-","G5351-","C5352-","G5353-","A5354-","T5355-","G5356-","A5357-","C5358-","A5359-","G5360-","A5361-","T5362-","C5363-","C5364-","C5365-","C5366-","T5367-","A5368-","T5369-","C5370-","C5371-","A5372-","C5373-","G5374-","G5375-","C5376-","C5377-","A5378-","C5379-","G5380-","T5381-","C5382-","A5383-","A5384-","G5385-","A5386-","C5387-","A5388-","T5389-","G5390-","T5391-","A5392-","T5393-","A5394-","T5395-","C5396-","C5397-","A5398-","T5399-","T5400-","A5401-","C5402-","T5403-","C5404-","A5405-","T5406-","T5407-","A5408-","C5409-","T5410-","G5411-","C5412-","G5413-","T5414-","T5415-","G5416-","A5417-","C5418-","A5419-","T5420-","T5421-","T5422-","G5423-","C5424-","T5425-","C5426-","C5427-","A5428-","T5429-","T5430-","T5431-","T5432-","C5433-","T5434-","A5435-","A5436-","T5437-","A5438-","G5439-","C5440-","C5441-","A5442-","T5443-","G5444-","A5445-","T5446-","A5447-","C5448-","T5449-","A5450-","A5451-","A5452-","T5453-","C5454-","T5455-","A5456-","T5457-","A5458-","T5459-","A5460-","A5461-","C5462-","C5463-","T5464-","G5465-","C5466-","A5467-","T5468-","A5469-","G5470-","A5471-","T5472-","A5473-","G5474-","C5475-","G5476-","C5477-","G5478-","A5479-","T5480-","A5481-","A5482-","A5483-","G5484-","C5485-","A5486-","A5487-","G5488-","G5489-","T5490-","C5491-","C5492-","T5493-","T5494-","C5495-","C5496-","A5497-","C5498-","C5499-","A5500-","G5501-","C5502-","A5503-","T5504-","C5505-","T5506-","A5507-","G5508-","T5509-","T5510-","G5511-","A5512-","T5513-","T5514-","G5515-","A5516-","T5517-","A5518-","T5519-","C5520-","T5521-","T5522-","C5523-","A5524-","A5525-","T5526-","A5527-","T5528-","A5529-","T5530-","G5531-","G5532-","G5533-","A5534-","T5535-","A5536-","C5537-","A5538-","A5539-","A5540-","G5541-","C5542-","T5543-","T5544-","A5545-","T5546-","A5547-","A5548-","A5549-","T5550-","T5551-","T5552-","C5553-","T5554-","A5555-","A5556-","T5557-","A5558-","C5559-","T5560-","G5561-","T5562-","G5563-","G5564-","G5565-","T5566-","T5567-","C5568-","A5569-","T5570-","C5571-","T5572-","A5573-","C5574-","A5575-","A5576-","G5577-","G5578-","A5579-","A5580-","T5581-","C5582-","C5583-","C5584-","C5585-","T5586-","A5587-","G5588-","T5589-","A5590-","T5591-","A5592-","C5593-","T5594-","G5595-","A5596-","A5597-","T5598-","T5599-","A5600-","T5601-","T5602-","T5603-","T5604-","A5605-","T5606-","A5607-","T5608-","A5609-","G5610-","A5611-","T5612-","C5613-","T5614-","A5615-","A5616-","T5617-","T5618-","T5619-","A5620-","A5621-","C5622-","A5623-","T5624-","C5625-","A5626-","T5627-","T5628-","T5629-","T5630-","C5631-","A5632-","T5633-","C5634-","T5635-","G5636-","G5637-","G5638-","A5639-","T5640-","A5641-","C5642-","C5643-","A5644-","C5645-","A5646-","A5647-","T5648-","T5649-","C5650-","A5651-","A5652-","A5653-","A5654-","T5655-","A5656-","A5657-","A5658-","C5659-","T5660-","C5661-","A5662-","A5663-","C5664-","A5665-","A5666-","C5667-","A5668-","C5669-","T5670-","A5671-","C5672-","T5673-","T5674-","T5675-","C5676-","C5677-","T5678-","T5679-","T5680-","T5681-","T5682-","A5683-","C5684-","A5685-","T5686-","A5687-","T5688-","T5689-","C5690-","C5691-","C5692-","C5693-","T5694-","A5695-","A5696-","A5697-","A5698-","T5699-","A5700-","G5701-","G5702-","C5703-","A5704-","T5705-","T5706-","C5707-","A5708-","A5709-","G5710-","C5711-","A5712-","T5713-","T5714-","C5715-","T5716-","A5717-","T5718-","T5719-","T5720-","T5721-","A5722-","T5723-","A5724-","T5725-","A5726-","T5727-","T5728-","A5729-","C5730-","A5731-","G5732-","C5733-","C5734-","C5735-","C5736-","A5737-","T5738-","G5739-","A5740-","T5741-","C5742-","T5743-","A5744-","C5745-","C5746-","A5747-","T5748-","A5749-","A5750-","G5751-","A5752-","T5753-","C5754-","A5755-","A5756-","C5757-","A5758-","A5759-","T5760-","G5761-","T5762-","C5763-","T5764-","A5765-","T5766-","T5767-","T5768-","C5769-","T5770-","A5771-","C5772-","A5773-","T5774-","A5775-","T5776-","G5777-","C5778-","A5779-","T5780-","T5781-","A5782-","G5783-","A5784-","T5785-","A5786-","G5787-","A5788-","T5789-","A5790-","G5791-","T5792-","A5793-","A5794-","A5795-","G5796-","T5797-","A5798-","A5799-","G5800-","A5801-","G5802-","A5803-","T5804-","C5805-","T5806-","T5807-","G5808-","C5809-","A5810-","C5811-","A5812-","G5813-","A5814-","A5815-","T5816-","T5817-","A5818-","C5819-","A5820-","A5821-","T5822-","T5823-","C5824-","T5825-","T5826-","A5827-","A5828-","T5829-","A5830-","A5831-","T5832-","T5833-","A5834-","T5835-","A5836-","G5837-","A5838-","G5839-","A5840-","A5841-","A5842-","A5843-","T5844-","A5845-","T5846-","C5847-","T5848-","T5849-","C5850-","C5851-","A5852-","T5853-","A5854-","T5855-","A5856-","A5857-","T5858-","T5859-","C5860-","T5861-","T5862-","T5863-","G5864-","A5865-","C5866-","A5867-","C5868-","T5869-","A5870-","A5871-","T5872-","G5873-","C5874-","A5875-","G5876-","A5877-","T5878-","A5879-","T5880-","A5881-","A5882-","T5883-","A5884-","T5885-","C5886-","T5887-","T5888-","T5889-","A5890-","T5891-","A5892-","T5893-","G5894-","T5895-","A5896-","A5897-","T5898-","A5899-","T5900-","A5901-","T5902-","G5903-","C5904-","A5905-","A5906-","A5907-","C5908-","A5909-","G5910-","T5911-","C5912-","T5913-","A5914-","T5915-","C5916-","T5917-","A5918-","C5919-","T5920-","A5921-","T5922-","A5923-","T5924-","A5925-","C5926-","T5927-","G5928-","A5929-","T5930-","C5931-","A5932-","A5933-","T5934-","A5935-","T5936-","T5937-","A5938-","T5939-","C5940-","T5941-","C5942-","T5943-","A5944-","T5945-","G5946-","A5947-","A5948-","T5949-","C5950-","C5951-","T5952-","A5953-","A5954-","A5955-","A5956-","T5957-","A5958-","A5959-","T5960-","C5961-","A5962-","T5963-","A5964-","C5965-","A5966-","G5967-","A5968-","A5969-","C5970-","A5971-","T5972-","C5973-","T5974-","A5975-","C5976-","A5977-","G5978-","G5979-","A5980-","T5981-","C5982-","A5983-","C5984-","A5985-","A5986-","A5987-","T5988-","T5989-","G5990-","G5991-","T5992-","T5993-","C5994-","A5995-","A5996-","G5997-","G5998-","A5999-","G6000-","A6001-","A6002-","A6003-","T6004-","C6005-","T6006-","A6007-","T6008-","C6009-","A6010-","A6011-","A6012-","T6013-","A6014-","T6015-","T6016-","T6017-","T6018-","C6019-","C6020-","T6021-","G6022-","T6023-","C6024-","A6025-","A6026-","C6027-","A6028-","A6029-","C6030-","T6031-","G6032-","G6033-","T6034-","T6035-","C6036-","T6037-","A6038-","G6039-","A6040-","A6041-","C6042-","A6043-","T6044-","A6045-","A6046-","C6047-","A6048-","G6049-","T6050-","C6051-","A6052-","A6053-","C6054-","A6055-","C6056-","C6057-","T6058-","A6059-","A6060-","T6061-","C6062-","C6063-","A6064-","T6065-","G6066-","T6067-","T6068-","T6069-","T6070-","T6071-","T6072-","A6073-","T6074-","A6075-","A6076-","T6077-","C6078-","A6079-","T6080-","C6081-","T6082-","A6083-","C6084-","C6085-","A6086-","A6087-","A6088-","G6089-","A6090-","T6091-","A6092-","A6093-","T6094-","G6095-","A6096-","C6097-","C6098-","A6099-","A6100-","A6101-","G6102-","A6103-","T6104-","C6105-","G6106-","A6107-","G6108-","G6109-","T6110-","C6111-","G6112-","T6113-","C6114-","G6115-","T6116-","G6117-","A6118-","A6119-","A6120-","C6121-","T6122-","G6123-","C6124-","T6125-","C6126-","A6127-","T6128-","C6129-","G6130-","A6131-","C6132-","A6133-","G6134-","C6135-","C6136-","A6137-","T6138-","G6139-","A6140-","A6141-","A6142-","T6143-","C6144-","T6145-","A6146-","C6147-","C6148-","G6149-","A6150-","C6151-","T6152-","C6153-","C6154-","A6155-","T6156-","G6157-","G6158-","T6159-","G6160-","C6161-","G6162-","A6163-","A6164-","T6165-","C6166-","G6167-","C6168-","A6169-","C6170-","T6171-","G6172-","T6173-","C6174-","T6175-","T6176-","A6177-","T6178-","T6179-","C6180-","G6181-","C6182-","C6183-","A6184-","T6185-","T6186-","G6187-","A6188-","T6189-","T6190-","T6191-","T6192-","C6193-","A6194-","T6195-","T6196-","T6197-","T6198-","T6199-","T6200-","A6201-","T6202-","A6203-","A6204-","T6205-","T6206-","A6207-","T6208-","G6209-","T6210-","A6211-","C6212-","A6213-","T6214-","G6215-","T6216-","T6217-","T6218-","T6219-","C6220-","C6221-","T6222-","T6223-","C6224-","T6225-","A6226-","T6227-","T6228-","C6229-","T6230-","C6231-","A6232-","A6233-","G6234-","A6235-","G6236-","T6237-","C6238-","T6239-","A6240-","C6241-","A6242-","A6243-","A6244-","A6245-","A6246-","T6247-","A6248-","T6249-","A6250-","T6251-","T6252-","T6253-","T6254-","T6255-","T6256-","C6257-","G6258-","A6259-","T6260-","A6261-","T6262-","C6263-","T6264-","A6265-","A6266-","G6267-","T6268-","A6269-","C6270-","T6271-","A6272-","A6273-","G6274-","T6275-","T6276-","T6277-","T6278-","T6279-","T6280-","T6281-","A6282-","C6283-","T6284-","G6285-","T6286-","T6287-","T6288-","T6289-","T6290-","G6291-","T6292-","T6293-","A6294-","C6295-","T6296-","G6297-","T6298-","C6299-","T6300-","T6301-","C6302-","C6303-","A6304-","T6305-","T6306-","C6307-","T6308-","T6309-","C6310-","T6311-","A6312-","A6313-","C6314-","T6315-","A6316-","A6317-","A6318-","G6319-","A6320-","T6321-","C6322-","T6323-","G6324-","A6325-","G6326-","A6327-","T6328-","A6329-","A6330-","A6331-","T6332-","T6333-","A6334-","T6335-","A6336-","C6337-","A6338-","A6339-","T6340-","C6341-","T6342-","T6343-","C6344-","G6345-","C6346-","T6347-","A6348-","T6349-","C6350-","G6351-","A6352-","A6353-","C6354-","C6355-","A6356-","T6357-","T6358-","T6359-","T6360-","T6361-","G6362-","T6363-","A6364-","G6365-","T6366-","C6367-","T6368-","A6369-","A6370-","A6371-","G6372-","C6373-","C6374-","T6375-","G6376-","A6377-","A6378-","G6379-","T6380-","A6381-","A6382-","T6383-","T6384-","A6385-","A6386-","C6387-","C6388-","A6389-","A6390-","C6391-","T6392-","G6393-","T6394-","T6395-","T6396-","T6397-","T6398-","A6399-","T6400-","T6401-","A6402-","G6403-","T6404-","G6405-","G6406-","C6407-","T6408-","T6409-","T6410-","T6411-","T6412-","T6413-","C6414-","G6415-","A6416-","T6417-","C6418-","T6419-","A6420-","T6421-","C6422-","C6423-","T6424-","C6425-","G6426-","T6427-","C6428-","C6429-","T6430-","C6431-","T6432-","C6433-","A6434-","T6435-","C6436-","A6437-","T6438-","C6439-","C6440-","T6441-","T6442-","A6443-","T6444-","A6445-","T6446-","T6447-","A6448-","T6449-","T6450-","A6451-","T6452-","C6453-","A6454-","T6455-","T6456-","A6457-","T6458-","T6459-","A6460-","T6461-","C6462-","A6463-","T6464-","A6465-","G6466-","T6467-","C6468-","T6469-","A6470-","T6471-","T6472-","A6473-","A6474-","A6475-","C6476-","A6477-","C6478-","A6479-","A6480-","A6481-","T6482-","C6483-","A6484-","T6485-","C6486-","T6487-","A6488-","C6489-","G6490-","T6491-","T6492-","T6493-","A6494-","T6495-","A6496-","A6497-","C6498-","A6499-","A6500-","C6501-","A6502-","T6503-","T6504-","C6505-","T6506-","C6507-","A6508-","T6509-","T6510-","A6511-","T6512-","T6513-","A6514-","A6515-","T6516-","T6517-","A6518-","G6519-","T6520-","T6521-","C6522-","T6523-","G6524-","T6525-","A6526-","G6527-","A6528-","A6529-","T6530-","A6531-","T6532-","C6533-","T6534-","T6535-","T6536-","A6537-","A6538-","T6539-","A6540-","A6541-","T6542-","T6543-","T6544-","G6545-","G6546-","C6547-","T6548-","A6549-","T6550-","A6551-","C6552-","A6553-","T6554-","C6555-","T6556-","G6557-","T6558-","T6559-","C6560-","A6561-","A6562-","T6563-","A6564-","C6565-","T6566-","A6567-","T6568-","C6569-","T6570-","A6571-","T6572-","T6573-","G6574-","A6575-","T6576-","G6577-","A6578-","T6579-","T6580-","T6581-","C6582-","T6583-","T6584-","T6585-","T6586-","T6587-","T6588-","A6589-","A6590-","G6591-","A6592-","C6593-","T6594-","T6595-","A6596-","A6597-","A6598-","C6599-","T6600-","A6601-","G6602-","T6603-","T6604-","A6605-","T6606-","G6607-","G6608-","T6609-","A6610-","A6611-","T6612-","G6613-","A6614-","C6615-","G6616-","A6617-","T6618-","G6619-","A6620-","A6621-","A6622-","T6623-","C6624-","G6625-","A6626-","G6627-","T6628-","A6629-","G6630-","T6631-","A6632-","A6633-","C6634-","T6635-","T6636-","C6637-","T6638-","A6639-","A6640-","T6641-","A6642-","A6643-","A6644-","G6645-","A6646-","C6647-","T6648-","T6649-","G6650-","A6651-","T6652-","A6653-","T6654-","C6655-","A6656-","T6657-","T6658-","A6659-","T6660-","C6661-","A6662-","T6663-","A6664-","T6665-","G6666-","T6667-","T6668-","T6669-","G6670-","A6671-","T6672-","C6673-","G6674-","T6675-","C6676-","A6677-","T6678-","A6679-","G6680-","T6681-","T6682-","A6683-","A6684-","T6685-","A6686-","G6687-","T6688-","G6689-","T6690-","G6691-","G6692-","C6693-","T6694-","A6695-","A6696-","A6697-","T6698-","G6699-","G6700-","T6701-","A6702-","C6703-","T6704-","G6705-","T6706-","T6707-","A6708-","A6709-","T6710-","A6711-","A6712-","G6713-","T6714-","T6715-","T6716-","A6717-","T6718-","A6719-","G6720-","A6721-","C6722-","A6723-","A6724-","T6725-","A6726-","T6727-","C6728-","A6729-","T6730-","A6731-","G6732-","T6733-","A6734-","T6735-","T6736-","T6737-","T6738-","C6739-","T6740-","T6741-","T6742-","C6743-","C6744-","A6745-","G6746-","A6747-","A6748-","T6749-","T6750-","A6751-","G6752-","A6753-","T6754-","T6755-","A6756-","T6757-","T6758-","T6759-","T6760-","T6761-","T6762-","T6763-","A6764-","A6765-","A6766-","T6767-","A6768-","C6769-","T6770-","G6771-","A6772-","T6773-","C6774-","C6775-","T6776-","C6777-","A6778-","C6779-","A6780-","A6781-","T6782-","T6783-","C6784-","C6785-","G6786-","T6787-","G6788-","A6789-","T6790-","G6791-","T6792-","A6793-","G6794-","C6795-","A6796-","G6797-","T6798-","A6799-","G6800-","T6801-","T6802-","G6803-","G6804-","T6805-","G6806-","C6807-","A6808-","T6809-","G6810-","G6811-","T6812-","C6813-","T6814-","A6815-","T6816-","A6817-","T6818-","C6819-","G6820-","T6821-","T6822-","A6823-","A6824-","A6825-","A6826-","T6827-","G6828-","T6829-","A6830-","T6831-","C6832-","A6833-","T6834-","A6835-","T6836-","A6837-","T6838-","A6839-","A6840-","T6841-","A6842-","G6843-","T6844-","T6845-","T6846-","T6847-","C6848-","T6849-","G6850-","A6851-","C6852-","G6853-","T6854-","G6855-","G6856-","A6857-","G6858-","T6859-","A6860-","C6861-","A6862-","G6863-","A6864-","A6865-","T6866-","T6867-","T6868-","T6869-","C6870-","G6871-","A6872-","T6873-","T6874-","A6875-","A6876-","T6877-","G6878-","A6879-","G6880-","T6881-","T6882-","C6883-","A6884-","T6885-","G6886-","G6887-","T6888-","A6889-","A6890-","G6891-","G6892-","A6893-","A6894-","G6895-","G6896-","G6897-","C6898-","A6899-","A6900-","A6901-","T6902-","G6903-","C6904-","C6905-","T6906-","G6907-","T6908-","A6909-","T6910-","A6911-","T6912-","A6913-","A6914-","T6915-","A6916-","T6917-","A6918-","C6919-","A6920-","T6921-","A6922-","A6923-","G6924-","T6925-","T6926-","A6927-","A6928-","T6929-","A6930-","G6931-","T6932-","T6933-","T6934-","T6935-","T6936-","T6937-","A6938-","T6939-","C6940-","A6941-","T6942-","A6943-","T6944-","T6945-","T6946-","T6947-","C6948-","T6949-","A6950-","A6951-","T6952-","A6953-","C6954-","C6955-","A6956-","T6957-","A6958-","A6959-","T6960-","A6961-","A6962-","A6963-","A6964-","A6965-","T6966-","T6967-","A6968-","T6969-","C6970-","A6971-","T6972-","T6973-","A6974-","T6975-","T6976-","G6977-","C6978-","G6979-","T6980-","T6981-","T6982-","G6983-","G6984-","T6985-","A6986-","G6987-","T6988-","T6989-","C6990-","T6991-","G6992-","C6993-","C6994-","C6995-","T6996-","A6997-","T6998-","C6999-","A7000-","T7001-","C7002-","T7003-","A7004-","T7005-","A7006-","T7007-","C7008-","A7009-","C7010-","T7011-","G7012-","T7013-","C7014-","A7015-","C7016-","T7017-","C7018-","T7019-","C7020-","G7021-","C7022-","T7023-","C7024-","T7025-","C7026-","A7027-","C7028-","T7029-","A7030-","T7031-","A7032-","T7033-","C7034-","T7035-","T7036-","C7037-","T7038-","A7039-","A7040-","A7041-","A7042-","T7043-","T7044-","A7045-","C7046-","A7047-","A7048-","A7049-","C7050-","A7051-","A7052-","C7053-","T7054-","G7055-","G7056-","A7057-","T7058-","A7059-","T7060-","T7061-","C7062-","G7063-","A7064-","T7065-","A7066-","A7067-","C7068-","A7069-","G7070-","C7071-","A7072-","T7073-","T7074-","T7075-","G7076-","T7077-","G7078-","T7079-","A7080-","G7081-","T7082-","T7083-","T7084-","T7085-","T7086-","G7087-","T7088-","C7089-","T7090-","T7091-","T7092-","T7093-","A7094-","C7095-","A7096-","G7097-","T7098-","A7099-","T7100-","A7101-","T7102-","A7103-","C7104-","G7105-","T7106-","T7107-","A7108-","T7109-","T7110-","G7111-","T7112-","C7113-","A7114-","A7115-","A7116-","A7117-","T7118-","C7119-","T7120-","A7121-","A7122-","A7123-","C7124-","A7125-","A7126-","A7127-","T7128-","A7129-","T7130-","T7131-","A7132-","G7133-","C7134-","A7135-","T7136-","A7137-","A7138-","T7139-","A7140-","C7141-","A7142-","T7143-","C7144-","T7145-","A7146-","T7147-","C7148-","T7149-","A7150-","T7151-","A7152-","A7153-","G7154-","A7155-","T7156-","C7157-","A7158-","G7159-","G7160-","A7161-","T7162-","C7163-","C7164-","A7165-","T7166-","G7167-","T7168-","T7169-","C7170-","G7171-","A7172-","G7173-","C7174-","A7175-","T7176-","A7177-","C7178-","T7179-","A7180-","G7181-","C7182-","C7183-","A7184-","T7185-","G7186-","T7187-","A7188-","T7189-","A7190-","T7191-","T7192-","T7193-","G7194-","T7195-","A7196-","A7197-","C7198-","T7199-","T7200-","C7201-","G7202-","T7203-","C7204-","G7205-","T7206-","A7207-","C7208-","A7209-","G7210-","C7211-","G7212-","T7213-","T7214-","A7215-","G7216-","A7217-","T7218-","C7219-","A7220-","A7221-","T7222-","A7223-","G7224-","A7225-","A7226-","T7227-","A7228-","A7229-","A7230-","C7231-","A7232-","A7233-","T7234-","C7235-","G7236-","T7237-","G7238-","T7239-","G7240-","A7241-","C7242-","G7243-","C7244-","A7245-","A7246-","C7247-","T7248-","T7249-","T7250-","T7251-","T7252-","T7253-","A7254-","C7255-","G7256-","A7257-","T7258-","C7259-","T7260-","A7261-","G7262-","T7263-","T7264-","G7265-","T7266-","A7267-","T7268-","G7269-","A7270-","G7271-","T7272-","T7273-","T7274-","A7275-","T7276-","C7277-","G7278-","T7279-","T7280-","T7281-","A7282-","C7283-","A7284-","T7285-","A7286-","A7287-","G7288-","C7289-","A7290-","A7291-","T7292-","T7293-","A7294-","A7295-","C7296-","G7297-","G7298-","C7299-","T7300-","T7301-","T7302-","A7303-","A7304-","C7305-","A7306-","G7307-","A7308-","T7309-","G7310-","A7311-","T7312-","C7313-","T7314-","G7315-","A7316-","G7317-","T7318-","A7319-","A7320-","T7321-","A7322-","A7323-","T7324-","A7325-","T7326-","A7327-","C7328-","C7329-","T7330-","C7331-","T7332-","G7333-","T7334-","T7335-","A7336-","T7337-","A7338-","C7339-","G7340-","T7341-","T7342-","T7343-","A7344-","A7345-","T7346-","G7347-","T7348-","T7349-","C7350-","A7351-","C7352-","G7353-","G7354-","T7355-","C7356-","T7357-","T7358-","A7359-","G7360-","T7361-","A7362-","T7363-","T7364-","T7365-","T7366-","T7367-","A7368-","G7369-","A7370-","T7371-","A7372-","T7373-","C7374-","A7375-","A7376-","T7377-","T7378-","G7379-","T7380-","G7381-","A7382-","T7383-","T7384-","T7385-","A7386-","C7387-","A7388-","C7389-","C7390-","A7391-","T7392-","A7393-","T7394-","T7395-","C7396-","G7397-","A7398-","C7399-","T7400-","C7401-","C7402-","C7403-","T7404-","T7405-","G7406-","T7407-","G7408-","T7409-","G7410-","T7411-","A7412-","A7413-","C7414-","G7415-","T7416-","T7417-","A7418-","G7419-","A7420-","A7421-","A7422-","T7423-","T7424-","C7425-","T7426-","A7427-","A7428-","A7429-","T7430-","C7431-","T7432-","A7433-","T7434-","A7435-","T7436-","T7437-","A7438-","T7439-","C7440-","T7441-","A7442-","T7443-","T7444-","A7445-","C7446-","A7447-","G7448-","C7449-","G7450-","T7451-","A7452-","A7453-","A7454-","A7455-","C7456-","A7457-","C7458-","A7459-","T7460-","T7461-","C7462-","A7463-","A7464-","T7465-","A7466-","T7467-","T7468-","G7469-","T7470-","A7471-","T7472-","T7473-","G7474-","T7475-","T7476-","A7477-","T7478-","T7479-","T7480-","T7481-","T7482-","A7483-","T7484-","A7485-","T7486-","T7487-","A7488-","T7489-","T7490-","T7491-","A7492-","C7493-","A7494-","C7495-","A7496-","A7497-","T7498-","T7499-","A7500-","A7501-","C7502-","A7503-","A7504-","T7505-","G7506-","T7507-","A7508-","T7509-","T7510-","A7511-","T7512-","T7513-","A7514-","G7515-","T7516-","T7517-","T7518-","A7519-","T7520-","A7521-","T7522-","T7523-","A7524-","C7525-","T7526-","G7527-","A7528-","A7529-","T7530-","T7531-","A7532-","A7533-","T7534-","A7535-","A7536-","T7537-","A7538-","T7539-","A7540-","A7541-","A7542-","A7543-","T7544-","T7545-","C7546-","C7547-","C7548-","A7549-","A7550-","T7551-","C7552-","T7553-","T7554-","G7555-","T7556-","C7557-","A7558-","T7559-","A7560-","A7561-","A7562-","C7563-","A7564-","C7565-","A7566-","A7567-","A7568-","A7569-","T7570-","C7571-","C7572-","A7573-","T7574-","T7575-","A7576-","A7577-","A7578-","A7579-","A7580-","T7581-","G7582-","T7583-","C7584-","G7585-","A7586-","T7587-","A7588-","A7589-","A7590-","A7591-","T7592-","A7593-","T7594-","C7595-","T7596-","G7597-","A7598-","T7599-","G7600-","T7601-","T7602-","G7603-","T7604-","T7605-","G7606-","T7607-","T7608-","C7609-","G7610-","C7611-","T7612-","G7613-","C7614-","T7615-","A7616-","T7617-","G7618-","A7619-","T7620-","A7621-","A7622-","T7623-","C7624-","A7625-","G7626-","A7627-","T7628-","C7629-","A7630-","T7631-","T7632-","A7633-","G7634-","C7635-","C7636-","G7637-","A7638-","T7639-","A7640-","G7641-","T7642-","G7643-","G7644-","T7645-","A7646-","A7647-","T7648-","G7649-","C7650-","T7651-","A7652-","T7653-","C7654-","G7655-","A7656-","A7657-","A7658-","C7659-","A7660-","A7661-","C7662-","A7663-","T7664-","C7665-","G7666-","C7667-","C7668-","A7669-","G7670-","A7671-","A7672-","A7673-","T7674-","T7675-","A7676-","C7677-","A7678-","A7679-","A7680-","C7681-","G7682-","C7683-","T7684-","A7685-","C7686-","A7687-","A7688-","C7689-","A7690-","G7691-","A7692-","T7693-","A7694-","T7695-","T7696-","C7697-","C7698-","A7699-","G7700-","C7701-","T7702-","A7703-","T7704-","C7705-","A7706-","G7707-","A7708-","T7709-","T7710-","A7711-","T7712-","G7713-","T7714-","G7715-","G7716-","T7717-","C7718-","C7719-","A7720-","G7721-","A7722-","G7723-","G7724-","G7725-","A7726-","G7727-","A7728-","T7729-","G7730-","G7731-","A7732-","T7733-","A7734-","T7735-","T7736-","G7737-","T7738-","T7739-","T7740-","A7741-","C7742-","A7743-","C7744-","G7745-","G7746-","T7747-","G7748-","A7749-","C7750-","T7751-","G7752-","T7753-","A7754-","T7755-","C7756-","C7757-","A7758-","C7759-","G7760-","C7761-","T7762-","A7763-","G7764-","A7765-","G7766-","A7767-","T7768-","A7769-","T7770-","C7771-","G7772-","A7773-","C7774-","G7775-","G7776-","T7777-","A7778-","T7779-","G7780-","T7781-","A7782-","T7783-","T7784-","G7785-","T7786-","A7787-","G7788-","A7789-","T7790-","G7791-","C7792-","T7793-","C7794-","T7795-","C7796-","A7797-","T7798-","G7799-","G7800-","T7801-","T7802-","A7803-","T7804-","A7805-","C7806-","A7807-","G7808-","G7809-","T7810-","A7811-","T7812-","T7813-","A7814-","G7815-","A7816-","T7817-","G7818-","T7819-","C7820-","A7821-","G7822-","C7823-","A7824-","T7825-","G7826-","T7827-","A7828-","G7829-","T7830-","A7831-","T7832-","T7833-","A7834-","G7835-","T7836-","A7837-","G7838-","A7839-","C7840-","T7841-","A7842-","T7843-","C7844-","A7845-","A7846-","C7847-","G7848-","T7849-","T7850-","C7851-","A7852-","G7853-","G7854-","A7855-","A7856-","A7857-","A7858-","C7859-","C7860-","A7861-","G7862-","A7863-","C7864-","A7865-","C7866-","T7867-","A7868-","C7869-","A7870-","A7871-","C7872-","A7873-","T7874-","C7875-","A7876-","T7877-","A7878-","T7879-","A7880-","T7881-","C7882-","C7883-","C7884-","A7885-","T7886-","C7887-","T7888-","C7889-","T7890-","A7891-","G7892-","G7893-","T7894-","A7895-","T7896-","T7897-","G7898-","T7899-","G7900-","C7901-","T7902-","T7903-","G7904-","T7905-","A7906-","T7907-","T7908-","A7909-","G7910-","T7911-","A7912-","G7913-","G7914-","C7915-","A7916-","T7917-","T7918-","A7919-","T7920-","T7921-","A7922-","T7923-","T7924-","A7925-","C7926-","G7927-","T7928-","G7929-","T7930-","T7931-","G7932-","T7933-","C7934-","T7935-","A7936-","T7937-","T7938-","A7939-","T7940-","C7941-","T7942-","G7943-","T7944-","T7945-","T7946-","A7947-","T7948-","A7949-","T7950-","G7951-","T7952-","T7953-","C7954-","A7955-","C7956-","T7957-","C7958-","G7959-","A7960-","A7961-","G7962-","A7963-","A7964-","C7965-","T7966-","A7967-","A7968-","A7969-","C7970-","T7971-","A7972-","C7973-","C7974-","T7975-","A7976-","T7977-","A7978-","C7979-","A7980-","A7981-","G7982-","A7983-","T7984-","A7985-","T7986-","G7987-","G7988-","T7989-","T7990-","G7991-","T7992-","G7993-","T7994-","T7995-","A7996-","T7997-","A7998-","T7999-","T8000-","T8001-","T8002-","T8003-","T8004-","A8005-","T8006-","A8007-","A8008-","A8009-","A8010-","T8011-","T8012-","T8013-","T8014-","T8015-","T8016-","T8017-","A8018-","T8019-","G8020-","A8021-","G8022-","T8023-","A8024-","T8025-","T8026-","T8027-","T8028-","T8029-","A8030-","C8031-","A8032-","A8033-","A8034-","A8035-","A8036-","T8037-","G8038-","T8039-","A8040-","T8041-","A8042-","T8043-","G8044-","T8045-","A8046-","T8047-","A8048-","A8049-","A8050-","A8051-","A8052-","A8053-","A8054-","A8055-","T8056-","A8057-","C8058-","T8059-","A8060-","A8061-","G8062-","T8063-","A8064-","T8065-","A8066-","C8067-","G8068-","A8069-","T8070-","G8071-","T8072-","A8073-","T8074-","C8075-","C8076-","T8077-","G8078-","T8079-","A8080-","T8081-","T8082-","A8083-","T8084-","T8085-","T8086-","G8087-","T8088-","A8089-","T8090-","T8091-","T8092-","A8093-","T8094-","C8095-","T8096-","A8097-","A8098-","A8099-","C8100-","A8101-","A8102-","T8103-","A8104-","C8105-","T8106-","T8107-","C8108-","T8109-","G8110-","C8111-","C8112-","T8113-","C8114-","T8115-","A8116-","G8117-","A8118-","T8119-","G8120-","G8121-","G8122-","A8123-","T8124-","A8125-","C8126-","A8127-","A8128-","A8129-","A8130-","A8131-","T8132-","T8133-","T8134-","T8135-","T8136-","T8137-","A8138-","T8139-","T8140-","T8141-","C8142-","A8143-","G8144-","C8145-","A8146-","T8147-","A8148-","T8149-","T8150-","A8151-","A8152-","A8153-","G8154-","T8155-","A8156-","A8157-","A8158-","A8159-","T8160-","C8161-","T8162-","A8163-","G8164-","T8165-","T8166-","A8167-","C8168-","C8169-","T8170-","T8171-","G8172-","A8173-","A8174-","A8175-","A8176-","T8177-","G8178-","A8179-","A8180-","T8181-","A8182-","C8183-","A8184-","G8185-","T8186-","G8187-","G8188-","G8189-","T8190-","G8191-","G8192-","T8193-","T8194-","C8195-","C8196-","G8197-","T8198-","A8199-","T8200-","C8201-","A8202-","C8203-","C8204-","A8205-","G8206-","T8207-","A8208-","A8209-","G8210-","A8211-","A8212-","C8213-","A8214-","T8215-","A8216-","A8217-","T8218-","A8219-","G8220-","T8221-","C8222-","G8223-","A8224-","A8225-","T8226-","A8227-","C8228-","A8229-","G8230-","T8231-","A8232-","T8233-","C8234-","C8235-","G8236-","A8237-","T8238-","T8239-","G8240-","A8241-","G8242-","A8243-","T8244-","T8245-","T8246-","T8247-","G8248-","C8249-","A8250-","T8251-","A8252-","C8253-","A8254-","A8255-","T8256-","A8257-","C8258-","T8259-","A8260-","G8261-","T8262-","C8263-","T8264-","A8265-","G8266-","A8267-","A8268-","A8269-","G8270-","A8271-","A8272-","A8273-","T8274-","T8275-","T8276-","G8277-","T8278-","A8279-","A8280-","T8281-","C8282-","A8283-","T8284-","C8285-","C8286-","T8287-","C8288-","T8289-","G8290-","T8291-","G8292-","A8293-","C8294-","A8295-","G8296-","G8297-","A8298-","G8299-","T8300-","C8301-","C8302-","A8303-","T8304-","A8305-","T8306-","A8307-","T8308-","C8309-","T8310-","G8311-","T8312-","A8313-","T8314-","C8315-","A8316-","T8317-","C8318-","G8319-","T8320-","C8321-","T8322-","A8323-","G8324-","T8325-","T8326-","T8327-","T8328-","T8329-","A8330-","T8331-","C8332-","A8333-","G8334-","T8335-","G8336-","T8337-","C8338-","C8339-","T8340-","A8341-","T8342-","G8343-","C8344-","T8345-","A8346-","T8347-","A8348-","T8349-","T8350-","C8351-","C8352-","T8353-","G8354-","T8355-","T8356-","A8357-","T8358-","C8359-","A8360-","T8361-","C8362-","A8363-","T8364-","T8365-","A8366-","G8367-","T8368-","T8369-","A8370-","A8371-","T8372-","G8373-","A8374-","A8375-","A8376-","A8377-","T8378-","A8379-","A8380-","C8381-","T8382-","C8383-","T8384-","C8385-","G8386-","T8387-","G8388-","C8389-","T8390-","T8391-","C8392-","A8393-","G8394-","A8395-","A8396-","A8397-","A8398-","G8399-","T8400-","C8401-","A8402-","A8403-","A8404-","T8405-","A8406-","T8407-","T8408-","G8409-","T8410-","A8411-","T8412-","C8413-","C8414-","A8415-","T8416-","A8417-","C8418-","A8419-","T8420-","A8421-","T8422-","A8423-","T8424-","C8425-","T8426-","C8427-","C8428-","A8429-","A8430-","A8431-","A8432-","C8433-","T8434-","A8435-","T8436-","C8437-","A8438-","C8439-","T8440-","T8441-","A8442-","T8443-","A8444-","C8445-","G8446-","T8447-","T8448-","T8449-","A8450-","T8451-","C8452-","T8453-","T8454-","T8455-","A8456-","A8457-","C8458-","G8459-","A8460-","A8461-","C8462-","A8463-","T8464-","A8465-","T8466-","A8467-","C8468-","C8469-","T8470-","A8471-","G8472-","A8473-","T8474-","G8475-","G8476-","T8477-","T8478-","A8479-","T8480-","T8481-","T8482-","A8483-","C8484-","T8485-","A8486-","A8487-","C8488-","A8489-","G8490-","A8491-","C8492-","A8493-","T8494-","T8495-","T8496-","T8497-","T8498-","T8499-","C8500-","A8501-","A8502-","G8503-","A8504-","T8505-","C8506-","T8507-","A8508-","T8509-","T8510-","G8511-","A8512-","C8513-","A8514-","A8515-","T8516-","A8517-","A8518-","C8519-","T8520-","C8521-","C8522-","T8523-","A8524-","T8525-","A8526-","G8527-","T8528-","T8529-","T8530-","C8531-","C8532-","A8533-","C8534-","A8535-","T8536-","C8537-","A8538-","A8539-","C8540-","C8541-","A8542-","A8543-","G8544-","T8545-","A8546-","A8547-","T8548-","G8549-","A8550-","T8551-","C8552-","A8553-","T8554-","C8555-","T8556-","A8557-","T8558-","T8559-","G8560-","T8561-","T8562-","A8563-","T8564-","A8565-","T8566-","A8567-","A8568-","C8569-","A8570-","A8571-","T8572-","A8573-","A8574-","C8575-","A8576-","T8577-","A8578-","A8579-","C8580-","T8581-","C8582-","T8583-","T8584-","T8585-","T8586-","C8587-","C8588-","A8589-","T8590-","T8591-","T8592-","T8593-","T8594-","A8595-","T8596-","C8597-","A8598-","G8599-","T8600-","A8601-","T8602-","C8603-","T8604-","A8605-","T8606-","A8607-","T8608-","C8609-","A8610-","A8611-","C8612-","G8613-","T8614-","C8615-","G8616-","T8617-","T8618-","G8619-","T8620-","A8621-","G8622-","T8623-","G8624-","A8625-","A8626-","T8627-","A8628-","G8629-","T8630-","A8631-","G8632-","T8633-","C8634-","A8635-","T8636-","T8637-","G8638-","A8639-","T8640-","C8641-","T8642-","A8643-","T8644-","T8645-","A8646-","T8647-","A8648-","T8649-","G8650-","A8651-","A8652-","A8653-","C8654-","G8655-","G8656-","A8657-","T8658-","A8659-","T8660-","G8661-","T8662-","C8663-","T8664-","A8665-","G8666-","T8667-","T8668-","A8669-","A8670-","T8671-","A8672-","T8673-","T8674-","T8675-","T8676-","C8677-","T8678-","T8679-","T8680-","G8681-","A8682-","T8683-","T8684-","T8685-","A8686-","A8687-","A8688-","G8689-","T8690-","C8691-","T8692-","A8693-","T8694-","A8695-","G8696-","T8697-","C8698-","T8699-","T8700-","T8701-","A8702-","C8703-","A8704-","A8705-","A8706-","C8707-","A8708-","T8709-","A8710-","A8711-","T8712-","A8713-","T8714-","C8715-","C8716-","T8717-","T8718-","A8719-","T8720-","C8721-","C8722-","G8723-","A8724-","C8725-","T8726-","T8727-","T8728-","A8729-","T8730-","A8731-","T8732-","T8733-","T8734-","C8735-","C8736-","T8737-","G8738-","T8739-","A8740-","G8741-","G8742-","G8743-","T8744-","G8745-","G8746-","C8747-","A8748-","T8749-","A8750-","A8751-","T8752-","T8753-","T8754-","T8755-","A8756-","T8757-","T8758-","C8759-","T8760-","G8761-","C8762-","C8763-","T8764-","C8765-","C8766-","A8767-","C8768-","A8769-","A8770-","T8771-","C8772-","A8773-","G8774-","T8775-","G8776-","T8777-","T8778-","T8779-","C8780-","C8781-","A8782-","A8783-","A8784-","T8785-","A8786-","T8787-","A8788-","T8789-","T8790-","A8791-","C8792-","T8793-","A8794-","G8795-","A8796-","C8797-","A8798-","A8799-","T8800-","A8801-","T8802-","T8803-","C8804-","C8805-","A8806-","T8807-","A8808-","T8809-","A8810-","G8811-","T8812-","T8813-","A8814-","T8815-","T8816-","A8817-","G8818-","T8819-","T8820-","A8821-","A8822-","G8823-","G8824-","G8825-","A8826-","C8827-","C8828-","C8829-","A8830-","A8831-","T8832-","T8833-","A8834-","G8835-","A8836-","A8837-","C8838-","A8839-","C8840-","G8841-","T8842-","A8843-","C8844-","G8845-","C8846-","G8847-","C8848-","T8849-","T8850-","A8851-","T8852-","T8853-","C8854-","A8855-","T8856-","C8857-","A8858-","T8859-","T8860-","T8861-","G8862-","G8863-","A8864-","T8865-","C8866-","G8867-","T8868-","A8869-","T8870-","T8871-","T8872-","C8873-","A8874-","T8875-","A8876-","A8877-","A8878-","A8879-","G8880-","T8881-","T8882-","A8883-","T8884-","T8885-","A8886-","T8887-","G8888-","T8889-","T8890-","A8891-","T8892-","A8893-","G8894-","A8895-","T8896-","G8897-","T8898-","C8899-","A8900-","A8901-","C8902-","A8903-","C8904-","A8905-","T8906-","T8907-","C8908-","T8909-","A8910-","C8911-","A8912-","T8913-","T8914-","T8915-","T8916-","T8917-","T8918-","T8919-","A8920-","A8921-","T8922-","T8923-","G8924-","T8925-","C8926-","T8927-","A8928-","T8929-","A8930-","T8931-","A8932-","G8933-","T8934-","A8935-","T8936-","T8937-","T8938-","T8939-","T8940-","C8941-","T8942-","G8943-","A8944-","T8945-","A8946-","T8947-","T8948-","T8949-","T8950-","C8951-","T8952-","A8953-","T8954-","A8955-","A8956-","T8957-","A8958-","T8959-","C8960-","A8961-","G8962-","A8963-","A8964-","T8965-","T8966-","G8967-","T8968-","C8969-","T8970-","T8971-","C8972-","C8973-","A8974-","T8975-","A8976-","G8977-","G8978-","A8979-","A8980-","G8981-","T8982-","T8983-","G8984-","T8985-","A8986-","T8987-","A8988-","C8989-","T8990-","A8991-","T8992-","T8993-","C8994-","G8995-","G8996-","A8997-","A8998-","T8999-","C9000-","A9001-","G9002-","T9003-","T9004-","A9005-","C9006-","A9007-","T9008-","G9009-","T9010-","T9011-","T9012-","A9013-","A9014-","A9015-","T9016-","A9017-","A9018-","T9019-","T9020-","C9021-","T9022-","C9023-","T9024-","G9025-","A9026-","T9027-","G9028-","T9029-","C9030-","A9031-","T9032-","T9033-","C9034-","C9035-","T9036-","T9037-","A9038-","T9039-","A9040-","C9041-","A9042-","A9043-","T9044-","C9045-","A9046-","A9047-","A9048-","T9049-","T9050-","C9051-","A9052-","T9053-","T9054-","A9055-","T9056-","T9057-","A9058-","A9059-","A9060-","C9061-","A9062-","G9063-","T9064-","T9065-","T9066-","A9067-","A9068-","T9069-","A9070-","G9071-","T9072-","C9073-","T9074-","G9075-","T9076-","A9077-","G9078-","A9079-","C9080-","C9081-","T9082-","T9083-","T9084-","A9085-","T9086-","C9087-","G9088-","T9089-","C9090-","G9091-","T9092-","A9093-","C9094-","A9095-","T9096-","A9097-","T9098-","C9099-","C9100-","A9101-","T9102-","T9103-","G9104-","T9105-","C9106-","T9107-","T9108-","A9109-","T9110-","T9111-","A9112-","G9113-","T9114-","T9115-","A9116-","C9117-","G9118-","C9119-","T9120-","T9121-","A9122-","T9123-","T9124-","T9125-","T9126-","T9127-","A9128-","T9129-","G9130-","G9131-","G9132-","T9133-","T9134-","T9135-","T9136-","A9137-","C9138-","G9139-","T9140-","T9141-","G9142-","C9143-","T9144-","T9145-","T9146-","A9147-","T9148-","T9149-","A9150-","T9151-","A9152-","T9153-","T9154-","T9155-","T9156-","A9157-","T9158-","A9159-","A9160-","T9161-","A9162-","A9163-","T9164-","G9165-","A9166-","T9167-","T9168-","G9169-","T9170-","T9171-","T9172-","G9173-","A9174-","C9175-","A9176-","A9177-","T9178-","G9179-","T9180-","C9181-","G9182-","T9183-","A9184-","G9185-","T9186-","A9187-","T9188-","A9189-","G9190-","A9191-","T9192-","A9193-","T9194-","A9195-","T9196-","T9197-","A9198-","T9199-","T9200-","A9201-","G9202-","A9203-","G9204-","G9205-","A9206-","G9207-","G9208-","T9209-","A9210-","T9211-","A9212-","A9213-","T9214-","T9215-","A9216-","T9217-","A9218-","A9219-","A9220-","A9221-","A9222-","G9223-","T9224-","T9225-","T9226-","C9227-","T9228-","G9229-","A9230-","G9231-","T9232-","A9233-","C9234-","G9235-","A9236-","T9237-","G9238-","T9239-","T9240-","A9241-","T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","C9257-","A9258-","T9259-","T9260-","A9261-","A9262-","C9263-","A9264-","T9265-","C9266-","A9267-","T9268-","A9269-","C9270-","A9271-","T9272-","C9273-","A9274-","A9275-","T9276-","T9277-","A9278-","A9279-","C9280-","T9281-","A9282-","C9283-","A9284-","T9285-","T9286-","C9287-","T9288-","T9289-","A9290-","T9291-","A9292-","A9293-","C9294-","A9295-","T9296-","T9297-","G9298-","T9299-","A9300-","A9301-","T9302-","C9303-","A9304-","A9305-","A9306-","A9307-","G9308-","A9309-","A9310-","T9311-","T9312-","G9313-","C9314-","A9315-","A9316-","T9317-","T9318-","T9319-","T9320-","G9321-","A9322-","T9323-","G9324-","T9325-","A9326-","T9327-","A9328-","A9329-","C9330-","A9331-","A9332-","C9333-","T9334-","G9335-","T9336-","C9337-","A9338-","A9339-","T9340-","G9341-","G9342-","A9343-","A9344-","T9345-","T9346-","G9347-","T9348-","A9349-","T9350-","A9351-","T9352-","T9353-","A9354-","C9355-","A9356-","A9357-","A9358-","T9359-","T9360-","A9361-","C9362-","G9363-","G9364-","T9365-","A9366-","T9367-","G9368-","T9369-","T9370-","G9371-","T9372-","A9373-","A9374-","C9375-","A9376-","A9377-","C9378-","A9379-","A9380-","A9381-","T9382-","A9383-","C9384-","C9385-","G9386-","A9387-","T9388-","C9389-","G9390-","G9391-","T9392-","A9393-","A9394-","T9395-","T9396-","G9397-","T9398-","C9399-","T9400-","C9401-","T9402-","G9403-","C9404-","C9405-","G9406-","C9407-","T9408-","G9409-","T9410-","A9411-","A9412-","T9413-","A9414-","G9415-","A9416-","A9417-","T9418-","T9419-","A9420-","A9421-","T9422-","T9423-","A9424-","T9425-","A9426-","T9427-","A9428-","T9429-","C9430-","T9431-","A9432-","T9433-","T9434-","A9435-","C9436-","A9437-","C9438-","C9439-","G9440-","G9441-","C9442-","C9443-","T9444-","T9445-","G9446-","T9447-","A9448-","T9449-","C9450-","A9451-","T9452-","A9453-","A9454-","T9455-","A9456-","A9457-","A9458-","G9459-","T9460-","T9461-","G9462-","T9463-","G9464-","G9465-","T9466-","A9467-","G9468-","T9469-","A9470-","T9471-","G9472-","A9473-","T9474-","C9475-","T9476-","C9477-","C9478-","A9479-","T9480-","A9481-","T9482-","T9483-","T9484-","A9485-","T9486-","A9487-","A9488-","T9489-","T9490-","T9491-","A9492-","G9493-","T9494-","A9495-","C9496-","T9497-","T9498-","T9499-","G9500-","T9501-","A9502-","T9503-","T9504-","T9505-","A9506-","G9507-","T9508-","T9509-","T9510-","T9511-","T9512-","T9513-","T9514-","G9515-","G9516-","A9517-","A9518-","T9519-","C9520-","A9521-","T9522-","A9523-","A9524-","A9525-","A9526-","A9527-","A9528-","A9529-","G9530-","T9531-","T9532-","T9533-","T9534-","A9535-","C9536-","T9537-","A9538-","A9539-","T9540-","T9541-","T9542-","A9543-","A9544-","A9545-","A9546-","T9547-","T9548-","T9549-","A9550-","A9551-","A9552-","A9553-","A9554-","G9555-","T9556-","A9557-","T9558-","T9559-","T9560-","A9561-","C9562-","A9563-","T9564-","T9565-","T9566-","T9567-","T9568-","C9569-","A9570-","C9571-","T9572-","G9573-","T9574-","T9575-","T9576-","A9577-","G9578-","T9579-","C9580-","G9581-","C9582-","G9583-","G9584-","A9585-","T9586-","A9587-","T9588-","G9589-","G9590-","A9591-","A9592-","T9593-","T9594-","C9595-","G9596-","A9597-","T9598-","C9599-","C9600-","T9601-","G9602-","T9603-","C9604-","A9605-","A9606-","A9607-","A9608-","T9609-","C9610-","A9611-","A9612-","T9613-","A9614-","C9615-","A9616-","T9617-","C9618-","A9619-","T9620-","C9621-","T9622-","A9623-","T9624-","A9625-","G9626-","A9627-","T9628-","C9629-","A9630-","T9631-","G9632-","T9633-","A9634-","A9635-","C9636-","A9637-","A9638-","T9639-","A9640-","T9641-","T9642-","A9643-","C9644-","A9645-","A9646-","T9647-","A9648-","C9649-","A9650-","T9651-","A9652-","G9653-","A9654-","T9655-","G9656-","A9657-","A9658-","C9659-","C9660-","A9661-","A9662-","A9663-","T9664-","G9665-","A9666-","T9667-","A9668-","T9669-","A9670-","A9671-","G9672-","A9673-","C9674-","T9675-","A9676-","A9677-","C9678-","A9679-","G9680-","T9681-","A9682-","T9683-","G9684-","C9685-","A9686-","T9687-","T9688-","A9689-","T9690-","C9691-","C9692-","G9693-","A9694-","A9695-","A9696-","T9697-","G9698-","T9699-","T9700-","A9701-","A9702-","T9703-","A9704-","A9705-","C9706-","A9707-","T9708-","T9709-","A9710-","C9711-","A9712-","T9713-","A9714-","T9715-","T9716-","A9717-","T9718-","A9719-","T9720-","C9721-","A9722-","A9723-","T9724-","A9725-","T9726-","C9727-","A9728-","C9729-","A9730-","A9731-","A9732-","A9733-","A9734-","T9735-","A9736-","A9737-","A9738-","T9739-","C9740-","C9741-","A9742-","C9743-","A9744-","T9745-","T9746-","T9747-","G9748-","G9749-","C9750-","T9751-","A9752-","A9753-","T9754-","C9755-","G9756-","A9757-","T9758-","T9759-","T9760-","C9761-","G9762-","G9763-","G9764-","C9765-","T9766-","T9767-","G9768-","G9769-","A9770-","A9771-","A9772-","A9773-","A9774-","A9775-","C9776-","G9777-","T9778-","A9779-","T9780-","C9781-","G9782-","C9783-","C9784-","G9785-","G9786-","A9787-","A9788-","G9789-","G9790-","G9791-","A9792-","C9793-","T9794-","A9795-","T9796-","A9797-","T9798-","G9799-","A9800-","C9801-","T9802-","A9803-","A9804-","C9805-","T9806-","T9807-","A9808-","T9809-","C9810-","T9811-","A9812-","G9813-","A9814-","G9815-","A9816-","T9817-","A9818-","C9819-","A9820-","G9821-","G9822-","A9823-","A9824-","T9825-","A9826-","C9827-","A9828-","A9829-","C9830-","A9831-","A9832-","T9833-","C9834-","A9835-","A9836-","A9837-","A9838-","C9839-","T9840-","T9841-","A9842-","C9843-","T9844-","G9845-","A9846-","A9847-","A9848-","C9849-","T9850-","A9851-","T9852-","A9853-","C9854-","G9855-","T9856-","A9857-","A9858-","C9859-","T9860-","G9861-","T9862-","C9863-","A9864-","A9865-","A9866-","A9867-","A9868-","A9869-","A9870-","T9871-","A9872-","A9873-","A9874-","A9875-","A9876-","C9877-","A9878-","T9879-","A9880-","T9881-","A9882-","T9883-","G9884-","G9885-","T9886-","C9887-","T9888-","A9889-","T9890-","A9891-","T9892-","A9893-","T9894-","A9895-","C9896-","A9897-","C9898-","T9899-","A9900-","C9901-","A9902-","A9903-","T9904-","T9905-","T9906-","A9907-","G9908-","T9909-","T9910-","A9911-","T9912-","T9913-","A9914-","A9915-","T9916-","G9917-","T9918-","G9919-","G9920-","T9921-","T9922-","A9923-","T9924-","T9925-","G9926-","A9927-","T9928-","T9929-","G9930-","G9931-","A9932-","T9933-","A9934-","A9935-","C9936-","C9937-","G9938-","A9939-","T9940-","G9941-","T9942-","G9943-","A9944-","T9945-","T9946-","G9947-","T9948-","T9949-","C9950-","A9951-","A9952-","T9953-","C9954-","A9955-","A9956-","T9957-","A9958-","T9959-","T9960-","A9961-","A9962-","G9963-","A9964-","G9965-","G9966-","G9967-","T9968-","T9969-","G9970-","G9971-","T9972-","A9973-","A9974-","A9975-","T9976-","T9977-","G9978-","G9979-","T9980-","A9981-","C9982-","A9983-","T9984-","A9985-","G9986-","C9987-","T9988-","A9989-","A9990-","T9991-","A9992-","A9993-","T9994-","A9995-","C9996-","A9997-","T9998-","A9999-","T10000-","A10001-","C10002-","T10003-","C10004-","C10005-","A10006-","A10007-","A10008-","T10009-","A10010-","C10011-","A10012-","C10013-","C10014-","C10015-","A10016-","A10017-","T10018-","A10019-","A10020-","T10021-","A10022-","C10023-","T10024-","A10025-","C10026-","A10027-","A10028-","C10029-","C10030-","A10031-","T10032-","T10033-","T10034-","C10035-","T10036-","G10037-","A10038-","G10039-","T10040-","T10041-","G10042-","G10043-","A10044-","T10045-","A10046-","T10047-","C10048-","A10049-","T10050-","C10051-","A10052-","A10053-","A10054-","A10055-","T10056-","A10057-","C10058-","T10059-","G10060-","G10061-","A10062-","T10063-","A10064-","A10065-","A10066-","T10067-","A10068-","C10069-","G10070-","A10071-","G10072-","G10073-","A10074-","C10075-","A10076-","T10077-","G10078-","T10079-","A10080-","T10081-","A10082-","G10083-","A10084-","G10085-","T10086-","A10087-","A10088-","G10089-","T10090-","A10091-","A10092-","A10093-","G10094-","A10095-","A10096-","A10097-","A10098-","A10099-","G10100-","A10101-","A10102-","T10103-","G10104-","T10105-","G10106-","G10107-","A10108-","A10109-","T10110-","T10111-","T10112-","G10113-","C10114-","T10115-","A10116-","T10117-","G10118-","A10119-","A10120-","G10121-","T10122-","T10123-","G10124-","T10125-","T10126-","T10127-","A10128-","C10129-","T10130-","C10131-","A10132-","A10133-","A10134-","A10135-","C10136-","G10137-","A10138-","T10139-","T10140-","A10141-","G10142-","A10143-","A10144-","A10145-","A10146-","C10147-","G10148-","A10149-","T10150-","A10151-","G10152-","A10153-","T10154-","A10155-","C10156-","T10157-","T10158-","T10159-","G10160-","G10161-","T10162-","T10163-","T10164-","A10165-","T10166-","T10167-","G10168-","G10169-","A10170-","T10171-","T10172-","C10173-","G10174-","T10175-","G10176-","T10177-","A10178-","A10179-","T10180-","C10181-","A10182-","T10183-","A10184-","T10185-","A10186-","T10187-","T10188-","T10189-","T10190-","G10191-","C10192-","A10193-","T10194-","A10195-","A10196-","C10197-","A10198-","T10199-","G10200-","T10201-","A10202-","T10203-","C10204-","A10205-","A10206-","T10207-","A10208-","T10209-","A10210-","T10211-","G10212-","G10213-","C10214-","A10215-","T10216-","A10217-","G10218-","A10219-","A10220-","C10221-","A10222-","C10223-","G10224-","A10225-","A10226-","G10227-","A10228-","G10229-","A10230-","A10231-","A10232-","C10233-","C10234-","G10235-","G10236-","T10237-","G10238-","C10239-","G10240-","T10241-","C10242-","A10243-","G10244-","A10245-","T10246-","A10247-","A10248-","T10249-","T10250-","G10251-","T10252-","C10253-","C10254-","T10255-","A10256-","T10257-","A10258-","T10259-","G10260-","C10261-","C10262-","G10263-","T10264-","A10265-","C10266-","A10267-","C10268-","G10269-","T10270-","T10271-","T10272-","T10273-","A10274-","A10275-","A10276-","A10277-","A10278-","A10279-","A10280-","T10281-","A10282-","A10283-","C10284-","A10285-","A10286-","T10287-","G10288-","A10289-","G10290-","C10291-","A10292-","A10293-","G10294-","T10295-","T10296-","C10297-","T10298-","A10299-","T10300-","A10301-","A10302-","G10303-","C10304-","T10305-","A10306-","G10307-","T10308-","T10309-","A10310-","A10311-","C10312-","T10313-","A10314-","A10315-","T10316-","A10317-","A10318-","A10319-","T10320-","A10321-","A10322-","A10323-","A10324-","A10325-","G10326-","T10327-","T10328-","T10329-","A10330-","A10331-","T10332-","T10333-","A10334-","T10335-","C10336-","G10337-","A10338-","C10339-","G10340-","A10341-","T10342-","A10343-","T10344-","A10345-","T10346-","G10347-","T10348-","C10349-","G10350-","T10351-","T10352-","A10353-","T10354-","T10355-","T10356-","T10357-","T10358-","C10359-","T10360-","C10361-","T10362-","C10363-","A10364-","T10365-","A10366-","T10367-","G10368-","A10369-","A10370-","A10371-","G10372-","A10373-","T10374-","T10375-","A10376-","A10377-","T10378-","T10379-","T10380-","G10381-","A10382-","T10383-","T10384-","C10385-","T10386-","A10387-","A10388-","T10389-","A10390-","T10391-","A10392-","A10393-","T10394-","C10395-","T10396-","T10397-","C10398-","A10399-","G10400-","T10401-","A10402-","T10403-","T10404-","G10405-","G10406-","A10407-","T10408-","G10409-","A10410-","A10411-","T10412-","C10413-","T10414-","C10415-","A10416-","A10417-","T10418-","T10419-","C10420-","A10421-","A10422-","A10423-","T10424-","T10425-","A10426-","A10427-","T10428-","T10429-","C10430-","C10431-","A10432-","T10433-","T10434-","A10435-","G10436-","A10437-","T10438-","T10439-","A10440-","G10441-","A10442-","T10443-","T10444-","A10445-","G10446-","A10447-","T10448-","T10449-","A10450-","G10451-","A10452-","T10453-","C10454-","A10455-","T10456-","A10457-","A10458-","A10459-","T10460-","A10461-","A10462-","A10463-","A10464-","A10465-","T10466-","A10467-","G10468-","T10469-","A10470-","G10471-","C10472-","A10473-","C10474-","G10475-","C10476-","A10477-","C10478-","T10479-","A10480-","C10481-","T10482-","T10483-","C10484-","A10485-","G10486-","C10487-","C10488-","A10489-","A10490-","A10491-","T10492-","A10493-","T10494-","T10495-","C10496-","T10497-","T10498-","T10499-","T10500-","T10501-","T10502-","G10503-","A10504-","A10505-","A10506-","C10507-","G10508-","C10509-","C10510-","A10511-","T10512-","C10513-","T10514-","A10515-","G10516-","C10517-","G10518-","T10519-","A10520-","A10521-","T10522-","G10523-","A10524-","G10525-","A10526-","A10527-","C10528-","A10529-","C10530-","A10531-","A10532-","G10533-","T10534-","G10535-","A10536-","A10537-","C10538-","C10539-","T10540-","A10541-","T10542-","A10543-","A10544-","T10545-","G10546-","A10547-","G10548-","C10549-","A10550-","A10551-","A10552-","T10553-","T10554-","T10555-","A10556-","T10557-","T10558-","A10559-","G10560-","T10561-","A10562-","T10563-","C10564-","G10565-","G10566-","T10567-","T10568-","A10569-","C10570-","A10571-","T10572-","G10573-","A10574-","A10575-","G10576-","G10577-","A10578-","C10579-","T10580-","T10581-","T10582-","A10583-","C10584-","G10585-","T10586-","A10587-","G10588-","A10589-","G10590-","T10591-","G10592-","G10593-","T10594-","G10595-","A10596-","T10597-","T10598-","C10599-","C10600-","T10601-","C10602-","C10603-","A10604-","T10605-","C10606-","T10607-","G10608-","T10609-","G10610-","G10611-","T10612-","A10613-","C10614-","G10615-","A10616-","A10617-","C10618-","G10619-","G10620-","T10621-","T10622-","T10623-","C10624-","A10625-","T10626-","C10627-","T10628-","T10629-","C10630-","T10631-","T10632-","T10633-","G10634-","A10635-","T10636-","G10637-","C10638-","C10639-","A10640-","C10641-","C10642-","A10643-","C10644-","C10645-","C10646-","A10647-","G10648-","A10649-","T10650-","G10651-","T10652-","T10653-","C10654-","T10655-","A10656-","T10657-","A10658-","A10659-","A10660-","C10661-","T10662-","T10663-","G10664-","G10665-","T10666-","A10667-","T10668-","C10669-","C10670-","T10671-","C10672-","G10673-","T10674-","C10675-","C10676-","G10677-","A10678-","T10679-","T10680-","T10681-","C10682-","A10683-","T10684-","A10685-","T10686-","C10687-","A10688-","T10689-","T10690-","T10691-","G10692-","C10693-","C10694-","A10695-","A10696-","C10697-","C10698-","A10699-","A10700-","T10701-","A10702-","C10703-","A10704-","T10705-","A10706-","T10707-","A10708-","G10709-","C10710-","T10711-","A10712-","A10713-","A10714-","C10715-","C10716-","C10717-","A10718-","G10719-","G10720-","C10721-","A10722-","T10723-","A10724-","C10725-","G10726-","T10727-","T10728-","C10729-","C10730-","A10731-","C10732-","A10733-","C10734-","A10735-","T10736-","C10737-","C10738-","G10739-","G10740-","A10741-","A10742-","C10743-","A10744-","A10745-","T10746-","G10747-","A10748-","A10749-","A10750-","T10751-","T10752-","C10753-","T10754-","C10755-","C10756-","A10757-","G10758-","A10759-","A10760-","G10761-","A10762-","T10763-","G10764-","T10765-","T10766-","A10767-","C10768-","A10769-","A10770-","T10771-","G10772-","G10773-","C10774-","T10775-","A10776-","G10777-","A10778-","T10779-","T10780-","T10781-","G10782-","G10783-","A10784-","C10785-","A10786-","T10787-","T10788-","T10789-","G10790-","G10791-","T10792-","T10793-","T10794-","C10795-","A10796-","A10797-","C10798-","C10799-","G10800-","C10801-","G10802-","T10803-","T10804-","A10805-","A10806-","C10807-","A10808-","T10809-","A10810-","T10811-","G10812-","A10813-","G10814-","T10815-","G10816-","A10817-","A10818-","C10819-","A10820-","C10821-","A10822-","C10823-","C10824-","C10825-","A10826-","T10827-","A10828-","C10829-","A10830-","T10831-","G10832-","A10833-","A10834-","A10835-","G10836-","C10837-","G10838-","A10839-","T10840-","G10841-","A10842-","G10843-","A10844-","A10845-","A10846-","T10847-","A10848-","G10849-","G10850-","A10851-","T10852-","T10853-","C10854-","T10855-","C10856-","A10857-","T10858-","C10859-","T10860-","T10861-","G10862-","C10863-","C10864-","A10865-","A10866-","A10867-","A10868-","T10869-","A10870-","T10871-","C10872-","A10873-","C10874-","T10875-","A10876-","T10877-","A10878-","A10879-","A10880-","A10881-","A10882-","A10883-","T10884-","T10885-","T10886-","A10887-","T10888-","T10889-","T10890-","A10891-","T10892-","C10893-","A10894-","A10895-","T10896-","T10897-","T10898-","T10899-","A10900-","A10901-","A10902-","G10903-","G10904-","T10905-","A10906-","T10907-","A10908-","A10909-","A10910-","A10911-","A10912-","A10913-","A10914-","T10915-","A10916-","C10917-","T10918-","T10919-","A10920-","T10921-","T10922-","G10923-","T10924-","T10925-","G10926-","C10927-","T10928-","C10929-","G10930-","A10931-","A10932-","T10933-","A10934-","T10935-","T10936-","T10937-","T10938-","G10939-","T10940-","A10941-","T10942-","T10943-","T10944-","G10945-","A10946-","T10947-","G10948-","G10949-","T10950-","A10951-","T10952-","A10953-","C10954-","G10955-","G10956-","A10957-","A10958-","G10959-","A10960-","T10961-","T10962-","A10963-","G10964-","A10965-","A10966-","A10967-","T10968-","G10969-","T10970-","A10971-","G10972-","G10973-","T10974-","A10975-","T10976-","T10977-","A10978-","T10979-","C10980-","A10981-","T10982-","C10983-","A10984-","A10985-","C10986-","T10987-","G10988-","A10989-","T10990-","T10991-","T10992-","T10993-","A10994-","T10995-","G10996-","A10997-","T10998-","G10999-","G11000-","T11001-","T11002-","T11003-","T11004-","A11005-","T11006-","G11007-","A11008-","A11009-","T11010-","T11011-","T11012-","T11013-","A11014-","T11015-","T11016-","A11017-","T11018-","G11019-","C11020-","T11021-","T11022-","C11023-","A11024-","C11025-","T11026-","A11027-","T11028-","T11029-","G11030-","C11031-","A11032-","T11033-","C11034-","G11035-","G11036-","A11037-","A11038-","A11039-","T11040-","A11041-","A11042-","T11043-","A11044-","T11045-","C11046-","A11047-","T11048-","A11049-","T11050-","G11051-","C11052-","T11053-","T11054-","C11055-","C11056-","A11057-","C11058-","G11059-","T11060-","A11061-","T11062-","A11063-","T11064-","T11065-","T11066-","T11067-","A11068-","T11069-","T11070-","T11071-","T11072-","G11073-","T11074-","T11075-","T11076-","T11077-","G11078-","A11079-","C11080-","T11081-","C11082-","A11083-","T11084-","A11085-","A11086-","T11087-","A11088-","C11089-","G11090-","C11091-","A11092-","C11093-","G11094-","T11095-","A11096-","A11097-","T11098-","T11099-","C11100-","T11101-","G11102-","G11103-","A11104-","T11105-","T11106-","A11107-","T11108-","T11109-","G11110-","G11111-","C11112-","A11113-","T11114-","A11115-","T11116-","C11117-","G11118-","A11119-","T11120-","G11121-","A11122-","A11123-","T11124-","A11125-","A11126-","T11127-","T11128-","T11129-","T11130-","A11131-","G11132-","C11133-","T11134-","C11135-","C11136-","A11137-","T11138-","G11139-","C11140-","T11141-","C11142-","A11143-","G11144-","T11145-","A11146-","A11147-","A11148-","T11149-","A11150-","T11151-","T11152-","A11153-","A11154-","T11155-","G11156-","A11157-","G11158-","A11159-","A11160-","C11161-","A11162-","T11163-","A11164-","G11165-","T11166-","G11167-","T11168-","T11169-","G11170-","C11171-","C11172-","T11173-","C11174-","C11175-","T11176-","A11177-","C11178-","C11179-","A11180-","T11181-","T11182-","A11183-","T11184-","T11185-","T11186-","T11187-","T11188-","T11189-","T11190-","C11191-","A11192-","T11193-","C11194-","T11195-","C11196-","A11197-","T11198-","T11199-","C11200-","A11201-","A11202-","T11203-","T11204-","C11205-","T11206-","T11207-","G11208-","A11209-","T11210-","T11211-","G11212-","C11213-","A11214-","G11215-","A11216-","G11217-","A11218-","T11219-","C11220-","T11221-","A11222-","T11223-","A11224-","T11225-","A11226-","A11227-","T11228-","C11229-","A11230-","T11231-","T11232-","A11233-","T11234-","A11235-","G11236-","C11237-","G11238-","T11239-","T11240-","G11241-","A11242-","C11243-","T11244-","T11245-","A11246-","T11247-","G11248-","G11249-","A11250-","C11251-","T11252-","C11253-","T11254-","G11255-","G11256-","A11257-","A11258-","T11259-","C11260-","T11261-","T11262-","A11263-","G11264-","A11265-","C11266-","G11267-","A11268-","T11269-","G11270-","T11271-","A11272-","C11273-","A11274-","G11275-","T11276-","C11277-","A11278-","T11279-","C11280-","T11281-","A11282-","T11283-","A11284-","A11285-","T11286-","C11287-","A11288-","T11289-","G11290-","G11291-","T11292-","A11293-","T11294-","A11295-","T11296-","T11297-","T11298-","A11299-","A11300-","T11301-","A11302-","C11303-","A11304-","T11305-","T11306-","G11307-","T11308-","T11309-","T11310-","T11311-","A11312-","T11313-","A11314-","G11315-","C11316-","A11317-","T11318-","A11319-","G11320-","G11321-","C11322-","A11323-","T11324-","T11325-","A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","C11727T","C39139T","-173314A","-173315T","-173316A","-173317T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A185259-","G185260-","A185261-","A185262-","T185263-","G185264-","T185265-","T185266-","T185267-","G185268-","C185269-","C185270-","A185271-","C185272-","A185273-","T185274-","T185275-","G185276-","G185277-","C185278-","T185279-","A185280-","G185281-","A185282-","G185283-","G185284-","A185285-","A185286-","T185287-","G185288-","C185289-","C185290-","G185291-","T185292-","T185293-","T185294-","A185295-","G185296-","A185297-","T185298-","C185299-","A185300-","A185301-","C185302-","G185303-","T185304-","A185305-","T185306-","T185307-","G185308-","C185309-","G185310-","A185311-","T185312-","A185313-","A185314-","C185315-","A185316-","G185317-","A185318-","C185319-","G185320-","A185321-","C185322-","G185323-","A185324-","T185325-","C185326-","A185327-","G185328-","G185329-","T185330-","T185331-","G185332-","T185333-","T185334-","A185335-","T185336-","T185337-","A185338-","T185339-","G185340-","C185341-","A185342-","G185343-","G185344-","A185345-","A185346-","T185347-","A185348-","C185349-","C185350-","A185351-","T185352-","T185353-","T185354-","C185355-","A185356-","T185357-","G185358-","A185359-","A185360-","G185361-","A185362-","T185363-","A185364-","G185365-","T185366-","G185367-","T185368-","A185369-","G185370-","A185371-","A185372-","A185373-","C185374-","A185375-","G185376-","A185377-","T185378-","A185379-","T185380-","A185381-","C185382-","A185383-","T185384-","T185385-","A185386-","T185387-","G185388-","G185389-","A185390-","C185391-","C185392-","A185393-","G185394-","A185395-","A185396-","A185397-","T185398-","A185399-","A185400-","T185401-","G185402-","T185403-","T185404-","A185405-","A185406-","A185407-","G185408-","G185409-","A185410-","A185411-","A185412-","C185413-","A185414-","T185415-","A185416-","T185417-","G185418-","A185419-","C185420-","A185421-","T185422-","A185423-","A185424-","A185425-","C185426-","A185427-","G185428-","T185429-","A185430-","T185431-","T185432-","G185433-","A185434-","C185435-","C185436-","C185437-","A185438-","C185439-","G185440-","A185441-","G185442-","T185443-","T185444-","A185445-","T185446-","A185447-","A185448-","C185449-","A185450-","A185451-","A185452-","G185453-","T185454-","C185455-","A185456-","A185457-","A185458-","G185459-","A185460-","C185461-","C185462-","C185463-","A185464-","T185465-","T185466-","T185467-","T185468-","C185469-","C185470-","T185471-","G185472-","C185473-","T185474-","C185475-","C185476-","A185477-","T185478-","T185479-","G185480-","A185481-","G185482-","T185483-","G185484-","T185485-","A185486-","A185487-","A185488-","A185489-","T185490-","T185491-","C185492-","A185493-","T185494-","G185495-","G185496-","T185497-","T185498-","G185499-","A185500-","C185501-","A185502-","A185503-","T185504-","T185505-","T185506-","A185507-","G185508-","G185509-","A185510-","A185511-","A185512-","T185513-","G185514-","G185515-","A185516-","T185517-","A185518-","T185519-","G185520-","A185521-","C185522-","A185523-","A185524-","C185525-","C185526-","C185527-","T185528-","A185529-","A185530-","T185531-","T185532-","C185533-","A185534-","T185535-","T185536-","T185537-","T185538-","G185539-","G185540-","G185541-","A185542-","A185543-","G185544-","A185545-","T185546-","G185547-","C185548-","T185549-","A185550-","A185551-","A185552-","A185553-","C185554-","T185555-","A185556-","A185557-","G185558-","A185559-","A185560-","A185561-","C185562-","G185563-","G185564-","A185565-","C185566-","A185567-","T185568-","A185569-","T185570-","A185571-","G185572-","T185573-","G185574-","C185575-","A185576-","A185577-","T185578-","G185579-","A185580-","C185581-","G185582-","A185583-","T185584-","A185585-","A185586-","A185587-","A185588-","G185589-","T185590-","C185591-","C185592-","T185593-","A185594-","C185595-","C185596-","A185597-","T185598-","G185599-","T185600-","A185601-","C185602-","A185603-","G185604-","T185605-","G185606-","A185607-","G185608-","A185609-","A185610-","A185611-","T185612-","A185613-","A185614-","A185615-","A185616-","A185617-","T185618-","A185619-","T185620-","A185621-","G185622-","A185623-","C185624-","T185625-","T185626-","T185627-","G185628-","G185629-","A185630-","T185631-","A185632-","T185633-","A185634-","A185635-","C185636-","T185637-","A185638-","T185639-","G185640-","G185641-","A185642-","G185643-","A185644-","T185645-","A185646-","T185647-","T185648-","A185649-","T185650-","T185651-","T185652-","C185653-","T185654-","A185655-","A185656-","T185657-","A185658-","T185659-","G185660-","G185661-","T185662-","T185663-","T185664-","A185665-","T185666-","C185667-","T185668-","A185669-","C185670-","A185671-","A185672-","T185673-","C185674-","T185675-","A185676-","C185677-","T185678-","A185679-","G185680-","T185681-","C185682-","A185683-","G185684-","G185685-","A185686-","T185687-","T185688-","A185689-","T185690-","G185691-","G185692-","A185693-","G185694-","A185695-","T185696-","G185697-","G185698-","T185699-","A185700-","C185701-","C185702-","A185703-","A185704-","A185705-","T185706-","A185707-","T185708-","A185709-","C185710-","A185711-","T185712-","T185713-","T185714-","A185715-","A185716-","A185717-","T185718-","C185719-","C185720-","G185721-","T185722-","A185723-","A185724-","C185725-","T185726-","A185727-","G185728-","A185729-","T185730-","C185731-","A185732-","G185733-","A185734-","T185735-","C185736-","A185737-","T185738-","G185739-","A185740-","G185741-","T185742-","G185743-","T185744-","G185745-","A185746-","A185747-","T185748-","C185749-","T185750-","A185751-","G185752-","C185753-","T185754-","T185755-","A185756-","G185757-","A185758-","T185759-","C185760-","T185761-","A185762-","A185763-","C185764-","G185765-","T185766-","C185767-","T185768-","A185769-","A185770-","G185771-","G185772-","A185773-","A185774-","G185775-","T185776-","A185777-","A185778-","C185779-","T185780-","G185781-","T185782-","G185783-","A185784-","C185785-","A185786-","T185787-","G185788-","T185789-","C185790-","C185791-","T185792-","G185793-","C185794-","G185795-","T185796-","T185797-","T185798-","A185799-","G185800-","T185801-","A185802-","T185803-","A185804-","C185805-","C185806-","A185807-","A185808-","G185809-","A185810-","A185811-","A185812-","T185813-","A185814-","T185815-","A185816-","T185817-","C185818-","A185819-","A185820-","C185821-","A185822-","T185823-","A185824-","T185825-","G185826-","A185827-","A185828-","G185829-","G185830-","T185831-","C185832-","T185833-","A185834-","T185835-","G185836-","C185837-","T185838-","T185839-","T185840-","A185841-","G185842-","T185843-","G185844-","T185845-","T185846-","A185847-","C185848-","T185849-","A185850-","C185851-","A185852-","T185853-","C185854-","T185855-","A185856-","A185857-","A185858-","G185859-","A185860-","T185861-","C185862-","A185863-","T185864-","T185865-","G185866-","T185867-","G185868-","C185869-","T185870-","A185871-","C185872-","A185873-","G185874-","G185875-","T185876-","A185877-","T185878-","T185879-","G185880-","G185881-","T185882-","T185883-","G185884-","G185885-","T185886-","T185887-","A185888-","A185889-","A185890-","A185891-","T185892-","C185893-","T185894-","A185895-","G185896-","T185897-","G185898-","G185899-","T185900-","T185901-","A185902-","T185903-","G185904-","G185905-","G185906-","A185907-","A185908-","G185909-","G185910-","A185911-","A185912-","G185913-","A185914-","T185915-","G185916-","C185917-","T185918-","G185919-","A185920-","T185921-","A185922-","A185923-","A185924-","C185925-","C185926-","A185927-","C185928-","G185929-","T185930-","G185931-","C185932-","T185933-","T185934-","G185935-","T185936-","T185937-","T185938-","T185939-","C185940-","A185941-","T185942-","C185943-","A185944-","T185945-","T185946-","G185947-","G185948-","A185949-","A185950-","T185951-","T185952-","A185953-","T185954-","T185955-","A185956-","C185957-","A185958-","C185959-","A185960-","C185961-","T185962-","G185963-","T185964-","C185965-","G185966-","T185967-","T185968-","G185969-","G185970-","A185971-","T185972-","T185973-","A185974-","T185975-","T185976-","A185977-","C185978-","T185979-","G185980-","T185981-","T185982-","C185983-","A185984-","T185985-","A185986-","C185987-","G185988-","A185989-","A185990-","G185991-","A185992-","T185993-","A185994-","T185995-","T185996-","T185997-","G185998-","G185999-","A186000-","G186001-","A186002-","A186003-","G186004-","C186005-","A186006-","C186007-","C186008-","T186009-","G186010-","G186011-","C186012-","C186013-","T186014-","G186015-","A186016-","C186017-","T186018-","A186019-","T186020-","G186021-","A186022-","T186023-","C186024-","C186025-","A186026-","T186027-","G186028-","T186029-","A186030-","A186031-","G186032-","T186033-","C186034-","A186035-","T186036-","A186037-","T186038-","A186039-","T186040-","C186041-","C186042-","A186043-","T186044-","A186045-","T186046-","A186047-","G186048-","A186049-","G186050-","T186051-","A186052-","T186053-","A186054-","G186055-","A186056-","G186057-","A186058-","T186059-","A186060-","C186061-","A186062-","T186063-","G186064-","G186065-","A186066-","T186067-","A186068-","G186069-","A186070-","A186071-","T186072-","C186073-","T186074-","A186075-","A186076-","T186077-","G186078-","T186079-","G186080-","T186081-","T186082-","A186083-","C186084-","A186085-","G186086-","C186087-","A186088-","A186089-","C186090-","C186091-","T186092-","C186093-","C186094-","T186095-","T186096-","A186097-","C186098-","A186099-","C186100-","A186101-","T186102-","T186103-","C186104-","G186105-","A186106-","A186107-","T186108-","T186109-","C186110-","A186111-","T186112-","T186113-","C186114-","A186115-","T186116-","G186117-","A186118-","C186119-","A186120-","A186121-","T186122-","T186123-","C186124-","T186125-","A186126-","A186127-","C186128-","G186129-","A186130-","A186131-","T186132-","A186133-","T186134-","G186135-","T186136-","G186137-","G186138-","A186139-","T186140-","A186141-","A186142-","A186143-","G186144-","A186145-","A186146-","A186147-","T186148-","T186149-","A186150-","G186151-","T186152-","A186153-","A186154-","C186155-","A186156-","A186157-","A186158-","T186159-","T186160-","A186161-","A186162-","A186163-","T186164-","G186165-","A186166-","T186167-","C186168-","T186169-","G186170-","T186171-","A186172-","C186173-","A186174-","A186175-","T186176-","G186177-","A186178-","A186179-","T186180-","A186181-","C186182-","A186183-","A186184-","G186185-","A186186-","A186187-","G186188-","A186189-","T186190-","T186191-","A186192-","T186193-","G186194-","G186195-","A186196-","A186197-","T186198-","A186199-","T186200-","A186201-","G186202-","C186203-","G186204-","A186205-","C186206-","G186207-","G186208-","A186209-","T186210-","C186211-","A186212-","T186213-","T186214-","G186215-","C186216-","C186217-","G186218-","G186219-","C186220-","G186221-","T186222-","C186223-","T186224-","A186225-","T186226-","A186227-","A186228-","A186229-","C186230-","A186231-","G186232-","A186233-","T186234-","T186235-","A186236-","G186237-","C186238-","A186239-","A186240-","A186241-","G186242-","G186243-","C186244-","A186245-","T186246-","T186247-","G186248-","A186249-","C186250-","T186251-","T186252-","C186253-","A186254-","G186255-","A186256-","G186257-","G186258-","G186259-","T186260-","A186261-","G186262-","A186263-","G186264-","A186265-","A186266-","A186267-","T186268-","A186269-","G186270-","C186271-","A186272-","A186273-","G186274-","T186275-","G186276-","T186277-","T186278-","A186279-","A186280-","T186281-","A186282-","T186283-","A186284-","G186285-","A186286-","T186287-","G186288-","G186289-","T186290-","A186291-","A186292-","T186293-","C186294-","T186295-","G186296-","T186297-","T186298-","A186299-","G186300-","A186301-","T186302-","A186303-","T186304-","C186305-","G186306-","C186307-","A186308-","T186309-","A186310-","T186311-","C186312-","A186313-","A186314-","G186315-","C186316-","A186317-","G186318-","A186319-","T186320-","A186321-","A186322-","G186323-","G186324-","A186325-","A186326-","A186327-","A186328-","G186329-","A186330-","T186331-","G186332-","G186333-","C186334-","C186335-","G186336-","A186337-","C186338-","A186339-","T186340-","A186341-","C186342-","A186343-","G186344-","A186345-","C186346-","A186347-","A186348-","G186349-","A186350-","A186351-","T186352-","A186353-","A186354-","A186355-","T186356-","G186357-","A186358-","T186359-","A186360-","T186361-","T186362-","A186363-","T186364-","T186365-","A186366-","G186367-","A186368-","G186369-","A186370-","T186371-","T186372-","T186373-","G186374-","T186375-","T186376-","T186377-","A186378-","T186379-","A186380-","C186381-","A186382-","C186383-","A186384-","C186385-","T186386-","C186387-","T186388-","A186389-","T186390-","C186391-","A186392-","G186393-","A186394-","C186395-","A186396-","A186397-","A186398-","G186399-","A186400-","T186401-","A186402-","T186403-","A186404-","A186405-","A186406-","A186407-","G186408-","A186409-","C186410-","A186411-","T186412-","T186413-","A186414-","T186415-","A186416-","G186417-","A186418-","A186419-","T186420-","C186421-","C186422-","G186423-","A186424-","A186425-","G186426-","A186427-","A186428-","G186429-","G186430-","T186431-","A186432-","A186433-","G186434-","A186435-","G186436-","A186437-","T186438-","G186439-","T186440-","T186441-","G186442-","T186443-","A186444-","T186445-","A186446-","A186447-","T186448-","A186449-","G186450-","A186451-","T186452-","G186453-","T186454-","T186455-","A186456-","A186457-","G186458-","A186459-","A186460-","C186461-","A186462-","A186463-","T186464-","C186465-","T186466-","T186467-","G186468-","T186469-","T186470-","A186471-","A186472-","A186473-","A186474-","A186475-","G186476-","T186477-","A186478-","C186479-","T186480-","A186481-","T186482-","T186483-","C186484-","T186485-","A186486-","T186487-","T186488-","G186489-","A186490-","T186491-","A186492-","A186493-","T186494-","T186495-","A186496-","T186497-","C186498-","T186499-","A186500-","T186501-","G186502-","T186503-","G186504-","A186505-","T186506-","A186507-","C186508-","T186509-","T186510-","T186511-","A186512-","G186513-","A186514-","T186515-","G186516-","A186517-","T186518-","T186519-","A186520-","T186521-","A186522-","T186523-","A186524-","T186525-","A186526-","C186527-","A186528-","C186529-","C186530-","T186531-","C186532-","T186533-","G186534-","T186535-","A186536-","G186537-","A186538-","A186539-","T186540-","A186541-","T186542-","A186543-","A186544-","C186545-","A186546-","A186547-","A186548-","T186549-","C186550-","C186551-","T186552-","A186553-","T186554-","G186555-","T186556-","G186557-","T186558-","T186559-","A186560-","G186561-","T186562-","A186563-","A186564-","A186565-","C186566-","G186567-","A186568-","T186569-","A186570-","C186571-","T186572-","T186573-","A186574-","T186575-","A186576-","T186577-","G186578-","A186579-","G186580-","C186581-","T186582-","A186583-","T186584-","G186585-","A186586-","C186587-","T186588-","A186589-","T186590-","C186591-","T186592-","T186593-","G186594-","A186595-","A186596-","T186597-","C186598-","A186599-","T186600-","C186601-","A186602-","G186603-","G186604-","T186605-","G186606-","T186607-","A186608-","G186609-","T186610-","T186611-","G186612-","T186613-","T186614-","C186615-","T186616-","A186617-","T186618-","C186619-","A186620-","T186621-","G186622-","T186623-","T186624-","A186625-","T186626-","G186627-","A186628-","A186629-","A186630-","T186631-","G186632-","A186633-","C186634-","T186635-","A186636-","T186637-","A186638-","A186639-","T186640-","C186641-","T186642-","C186643-","C186644-","T186645-","T186646-","G186647-","G186648-","A186649-","T186650-","A186651-","C186652-","A186653-","A186654-","A186655-","A186656-","G186657-","A186658-","C186659-","G186660-","C186661-","C186662-","A186663-","A186664-","A186665-","G186666-","A186667-","T186668-","G186669-","C186670-","T186671-","A186672-","T186673-","A186674-","G186675-","A186676-","A186677-","G186678-","A186679-","T186680-","G186681-","T186682-","G186683-","A186684-","T186685-","A186686-","G186687-","T186688-","A186689-","G186690-","C186691-","A186692-","A186693-","G186694-","T186695-","G186696-","C186697-","G186698-","G186699-","T186700-","A186701-","G186702-","C186703-","C186704-","G186705-","A186706-","A186707-","G186708-","C186709-","A186710-","T186711-","T186712-","G186713-","A186714-","A186715-","T186716-","G186717-","A186718-","C186719-","A186720-","T186721-","G186722-","T186723-","T186724-","T186725-","A186726-","A186727-","G186728-","G186729-","A186730-","A186731-","T186732-","T186733-","T186734-","G186735-","A186736-","T186737-","A186738-","A186739-","A186740-","A186741-","A186742-","C186743-","G186744-","T186745-","A186746-","A186747-","G186748-","T186749-","G186750-","C186751-","T186752-","A186753-","T186754-","T186755-","A186756-","T186757-","A186758-","A186759-","T186760-","A186761-","A186762-","A186763-","A186764-","G186765-","A186766-","A186767-","G186768-","A186769-","A186770-","G186771-","A186772-","T186773-","A186774-","A186775-","T186776-","T186777-","A186778-","T186779-","C186780-","T186781-","A186782-","A186783-","A186784-","C186785-","A186786-","G186787-","T186788-","T186789-","C186790-","G186791-","C186792-","C186793-","C186794-","G186795-","A186796-","T186797-","A186798-","T186799-","C186800-","T186801-","A186802-","C186803-","C186804-","A186805-","T186806-","A186807-","T186808-","A186809-","A186810-","T186811-","A186812-","T186813-","A186814-","T186815-","A186816-","T186817-","C186818-","A186819-","T186820-","A186821-","G186822-","G186823-","T186824-","G186825-","G186826-","C186827-","A186828-","C186829-","T186830-","A186831-","T186832-","T186833-","C186834-","T186835-","G186836-","C186837-","T186838-","A186839-","C186840-","T186841-","G186842-","T186843-","T186844-","A186845-","G186846-","T186847-","C186848-","A186849-","T186850-","T186851-","A186852-","T186853-","T186854-","T186855-","T186856-","A186857-","A186858-","T186859-","A186860-","T186861-","T186862-","G186863-","G186864-","C186865-","A186866-","A186867-","T186868-","T186869-","T186870-","A186871-","T186872-","A186873-","T186874-","A186875-","G186876-","C186877-","G186878-","C186879-","G186880-","C186881-","A186882-","A186883-","T186884-","A186885-","A186886-","A186887-","T186888-","A186889-","C186890-","A186891-","G186892-","A186893-","A186894-","C186895-","C186896-","A186897-","G186898-","G186899-","A186900-","A186901-","A186902-","T186903-","A186904-","T186905-","G186906-","A186907-","A186908-","A186909-","T186910-","A186911-","A186912-","T186913-","G186914-","A186915-","A186916-","A186917-","T186918-","A186919-","T186920-","G186921-","A186922-","C186923-","A186924-","A186925-","T186926-","A186927-","T186928-","G186929-","A186930-","G186931-","C186932-","A186933-","T186934-","T186935-","A186936-","A186937-","A186938-","T186939-","C186940-","T186941-","G186942-","A186943-","G186944-","C186945-","A186946-","T186947-","C186948-","A186949-","T186950-","G186951-","A186952-","T186953-","A186954-","G186955-","T186956-","C186957-","T186958-","T186959-","G186960-","A186961-","A186962-","A186963-","C186964-","A186965-","G186966-","T186967-","G186968-","T186969-","C186970-","T186971-","A186972-","T186973-","G186974-","G186975-","A186976-","A186977-","A186978-","T186979-","T186980-","A186981-","T186982-","T186983-","G186984-","A186985-","T186986-","A186987-","A186988-","T186989-","C186990-","G186991-","G186992-","T186993-","A186994-","C186995-","T186996-","A186997-","A186998-","T186999-","A187000-","A187001-","A187002-","A187003-","T187004-","A187005-","G187006-","T187007-","T187008-","T187009-","A187010-","A187011-","C187012-","T187013-","C187014-","T187015-","T187016-","T187017-","T187018-","A187019-","G187020-","A187021-","A187022-","C187023-","C187024-","A187025-","G187026-","T187027-","T187028-","T187029-","G187030-","G187031-","T187032-","A187033-","C187034-","T187035-","G187036-","T187037-","A187038-","A187039-","T187040-","T187041-","T187042-","C187043-","A187044-","G187045-","T187046-","T187047-","C187048-","A187049-","T187050-","T187051-","A187052-","C187053-","T187054-","C187055-","G187056-","T187057-","T187058-","G187059-","A187060-","G187061-","A187062-","A187063-","T187064-","A187065-","T187066-","T187067-","G187068-","A187069-","T187070-","G187071-","A187072-","T187073-","T187074-","T187075-","T187076-","T187077-","T187078-","T187079-","T187080-","A187081-","A187082-","A187083-","T187084-","G187085-","A187086-","G187087-","T187088-","A187089-","T187090-","C187091-","G187092-","G187093-","T187094-","A187095-","G187096-","T187097-","T187098-","A187099-","C187100-","A187101-","T187102-","A187103-","T187104-","T187105-","A187106-","C187107-","C187108-","A187109-","T187110-","A187111-","T187112-","C187113-","A187114-","T187115-","C187116-","C187117-","A187118-","T187119-","T187120-","A187121-","T187122-","A187123-","T187124-","A187125-","A187126-","T187127-","C187128-","G187129-","A187130-","T187131-","G187132-","A187133-","T187134-","G187135-","C187136-","A187137-","T187138-","G187139-","T187140-","A187141-","T187142-","T187143-","A187144-","G187145-","A187146-","A187147-","T187148-","A187149-","C187150-","T187151-","T187152-","T187153-","C187154-","C187155-","G187156-","A187157-","A187158-","T187159-","A187160-","A187161-","G187162-","T187163-","C187164-","T187165-","T187166-","C187167-","T187168-","A187169-","A187170-","A187171-","T187172-","A187173-","T187174-","T187175-","G187176-","T187177-","A187178-","T187179-","T187180-","A187181-","A187182-","T187183-","T187184-","A187185-","T187186-","G187187-","A187188-","A187189-","A187190-","A187191-","A187192-","C187193-","T187194-","A187195-","T187196-","G187197-","C187198-","T187199-","A187200-","T187201-","G187202-","T187203-","G187204-","A187205-","G187206-","T187207-","A187208-","T187209-","G187210-","A187211-","T187212-","T187213-","C187214-","A187215-","A187216-","A187217-","G187218-","A187219-","T187220-","G187221-","T187222-","T187223-","T187224-","A187225-","A187226-","T187227-","G187228-","A187229-","T187230-","A187231-","C187232-","G187233-","A187234-","T187235-","A187236-","C187237-","T187238-","A187239-","G187240-","A187241-","T187242-","T187243-","T187244-","T187245-","A187246-","T187247-","C187248-","T187249-","C187250-","T187251-","A187252-","G187253-","C187254-","G187255-","A187256-","G187257-","A187258-","T187259-","T187260-","G187261-","T187262-","T187263-","T187264-","A187265-","G187266-","A187267-","A187268-","T187269-","C187270-","A187271-","T187272-","T187273-","T187274-","A187275-","T187276-","C187277-","A187278-","T187279-","A187280-","A187281-","C187282-","T187283-","A187284-","T187285-","G187286-","T187287-","T187288-","T187289-","A187290-","A187291-","T187292-","A187293-","A187294-","A187295-","T187296-","T187297-","C187298-","A187299-","T187300-","C187301-","A187302-","A187303-","C187304-","G187305-","A187306-","A187307-","T187308-","A187309-","T187310-","C187311-","G187312-","A187313-","T187314-","A187315-","A187316-","A187317-","G187318-","A187319-","C187320-","C187321-","T187322-","C187323-","T187324-","T187325-","G187326-","T187327-","A187328-","A187329-","T187330-","T187331-","C187332-","G187333-","A187334-","G187335-","T187336-","A187337-","T187338-","A187339-","G187340-","G187341-","A187342-","A187343-","G187344-","T187345-","A187346-","G187347-","T187348-","A187349-","T187350-","T187351-","A187352-","C187353-","C187354-","A187355-","T187356-","A187357-","T187358-","C187359-","A187360-","A187361-","C187362-","T187363-","T187364-","C187365-","C187366-","G187367-","A187368-","G187369-","T187370-","T187371-","A187372-","A187373-","C187374-","A187375-","A187376-","T187377-","T187378-","A187379-","C187380-","T187381-","C187382-","T187383-","A187384-","A187385-","A187386-","A187387-","C187388-","A187389-","T187390-","G187391-","A187392-","G187393-","G187394-","A187395-","T187396-","T187397-","G187398-","T187399-","A187400-","C187401-","T187402-","C187403-","C187404-","T187405-","G187406-","T187407-","C187408-","T187409-","T187410-","T187411-","A187412-","T187413-","T187414-","G187415-","G187416-","A187417-","G187418-","A187419-","T187420-","C187421-","A187422-","C187423-","T187424-","A187425-","T187426-","T187427-","T187428-","A187429-","G187430-","T187431-","C187432-","G187433-","T187434-","T187435-","G187436-","A187437-","T187438-","A187439-","A187440-","A187441-","C187442-","T187443-","A187444-","G187445-","T187446-","A187447-","A187448-","C187449-","C187450-","T187451-","C187452-","A187453-","G187454-","G187455-","T187456-","T187457-","T187458-","C187459-","T187460-","T187461-","T187462-","A187463-","C187464-","A187465-","A187466-","A187467-","C187468-","G187469-","A187470-","T187471-","A187472-","A187473-","A187474-","G187475-","T187476-","A187477-","C187478-","A187479-","A187480-","C187481-","A187482-","T187483-","C187484-","A187485-","A187486-","G187487-","A187488-","C187489-","C187490-","T187491-","C187492-","A187493-","C187494-","A187495-","A187496-","C187497-","A187498-","C187499-","A187500-","G187501-","T187502-","G187503-","C187504-","A187505-","A187506-","G187507-","A187508-","T187509-","T187510-","A187511-","A187512-","T187513-","C187514-","T187515-","A187516-","G187517-","A187518-","A187519-","A187520-","T187521-","C187522-","A187523-","A187524-","A187525-","T187526-","G187527-","T187528-","A187529-","A187530-","T187531-","T187532-","C187533-","T187534-","G187535-","G187536-","A187537-","G187538-","G187539-","A187540-","G187541-","A187542-","A187543-","T187544-","C187545-","T187546-","A187547-","G187548-","A187549-","C187550-","A187551-","A187552-","C187553-","T187554-","A187555-","A187556-","C187557-","A187558-","C187559-","C187560-","C187561-","A187562-","C187563-","G187564-","G187565-","C187566-","G187567-","A187568-","A187569-","G187570-","T187571-","A187572-","T187573-","A187574-","C187575-","T187576-","T187577-","T187578-","A187579-","T187580-","G187581-","C187582-","C187583-","T187584-","C187585-","A187586-","T187587-","T187588-","C187589-","A187590-","G187591-","A187592-","A187593-","A187594-","C187595-","G187596-","G187597-","T187598-","A187599-","A187600-","C187601-","T187602-","G187603-","T187604-","A187605-","G187606-","T187607-","A187608-","G187609-","G187610-","A187611-","G187612-","A187613-","C187614-","T187615-","G187616-","T187617-","C187618-","T187619-","C187620-","T187621-","C187622-","T187623-","A187624-","A187625-","T187626-","C187627-","T187628-","C187629-","G187630-","A187631-","T187632-","G187633-","T187634-","A187635-","T187636-","A187637-","T187638-","A187639-","T187640-","A187641-","A187642-","T187643-","A187644-","T187645-","A187646-","T187647-","A187648-","C187649-","C187650-","A187651-","A187652-","T187653-","A187654-","C187655-","G187656-","G187657-","A187658-","C187659-","G187660-","C187661-","G187662-","A187663-","T187664-","A187665-","T187666-","A187667-","T187668-","T187669-","C187670-","C187671-","G187672-","A187673-","C187674-","A187675-","T187676-","G187677-","A187678-","A187679-","T187680-","G187681-","G187682-","C187683-","G187684-","T187685-","C187686-","G187687-","C187688-","T187689-","T187690-","A187691-","T187692-","C187693-","A187694-","T187695-","A187696-","T187697-","G187698-","T187699-","T187700-","A187701-","T187702-","A187703-","T187704-","C187705-","C187706-","T187707-","A187708-","A187709-","A187710-","T187711-","G187712-","T187713-","T187714-","G187715-","A187716-","T187717-","C187718-","A187719-","T187720-","A187721-","T187722-","T187723-","C187724-","C187725-","A187726-","C187727-","A187728-","A187729-","A187730-","T187731-","G187732-","A187733-","T187734-","T187735-","G187736-","T187737-","G187738-","A187739-","A187740-","C187741-","G187742-","A187743-","G187744-","A187745-","T187746-","T187747-","A187748-","A187749-","A187750-","T187751-","C187752-","A187753-","T187754-","C187755-","T187756-","A187757-","A187758-","C187759-","A187760-","A187761-","A187762-","T187763-","A187764-","A187765-","T187766-","T187767-","A187768-","G187769-","T187770-","T187771-","T187772-","T187773-","T187774-","T187775-","A187776-","T187777-","G187778-","A187779-","C187780-","A187781-","T187782-","T187783-","A187784-","A187785-","C187786-","A187787-","T187788-","A187789-","T187790-","A187791-","A187792-","T187793-","A187794-","A187795-","A187796-","T187797-","A187798-","A187799-","A187800-","T187801-","T187802-","A187803-","A187804-","T187805-","C187806-","A187807-","T187808-","T187809-","A187810-","T187811-","T187812-","G187813-","A187814-","C187815-","T187816-","T187817-","A187818-","A187819-","C187820-","G187821-","A187822-","T187823-","G187824-","A187825-","C187826-","G187827-","A187828-","A187829-","A187830-","G187831-","T187832-","T187833-","A187834-","T187835-","C187836-","A187837-","T187838-","T187839-","A187840-","T187841-","C187842-","T187843-","T187844-","A187845-","G187846-","G187847-","A187848-","T187849-","T187850-","C187851-","T187852-","T187853-","G187854-","A187855-","T187856-","T187857-","A187858-","T187859-","T187860-","A187861-","A187862-","T187863-","A187864-","C187865-","A187866-","A187867-","A187868-","T187869-","T187870-","C187871-","G187872-","T187873-","T187874-","G187875-","T187876-","G187877-","T187878-","C187879-","T187880-","A187881-","T187882-","G187883-","A187884-","A187885-","A187886-","T187887-","G187888-","T187889-","G187890-","A187891-","A187892-","C187893-","A187894-","A187895-","G187896-","G187897-","T187898-","G187899-","T187900-","C187901-","T187902-","C187903-","A187904-","T187905-","A187906-","T187907-","T187908-","A187909-","T187910-","A187911-","A187912-","T187913-","G187914-","C187915-","A187916-","C187917-","A187918-","A187919-","G187920-","A187921-","A187922-","T187923-","T187924-","A187925-","A187926-","A187927-","G187928-","T187929-","G187930-","T187931-","T187932-","G187933-","T187934-","A187935-","A187936-","A187937-","C187938-","T187939-","A187940-","T187941-","C187942-","T187943-","A187944-","G187945-","C187946-","C187947-","A187948-","G187949-","G187950-","A187951-","A187952-","C187953-","A187954-","T187955-","A187956-","T187957-","T187958-","C187959-","A187960-","G187961-","A187962-","T187963-","T187964-","A187965-","T187966-","C187967-","G187968-","A187969-","T187970-","G187971-","T187972-","G187973-","A187974-","T187975-","A187976-","A187977-","A187978-","T187979-","A187980-","C187981-","A187982-","G187983-","C187984-","G187985-","A187986-","T187987-","A187988-","C187989-","C187990-","A187991-","T187992-","C187993-","T187994-","G187995-","T187996-","G187997-","G187998-","A187999-","C188000-","A188001-","T188002-","T188003-","G188004-","T188005-","C188006-","C188007-","A188008-","A188009-","G188010-","T188011-","G188012-","A188013-","C188014-","A188015-","C188016-","A188017-","T188018-","T188019-","C188020-","A188021-","C188022-","G188023-","T188024-","C188025-","A188026-","A188027-","T188028-","A188029-","T188030-","A188031-","T188032-","A188033-","A188034-","T188035-","C188036-","G188037-","T188038-","T188039-","C188040-","T188041-","C188042-","C188043-","T188044-","C188045-","G188046-","G188047-","T188048-","G188049-","T188050-","C188051-","A188052-","T188053-","A188054-","G188055-","T188056-","T188057-","G188058-","T188059-","A188060-","G188061-","A188062-","G188063-","G188064-","T188065-","C188066-","A188067-","C188068-","A188069-","C188070-","C188071-","T188072-","T188073-","G188074-","T188075-","A188076-","C188077-","A188078-","C188079-","C188080-","T188081-","A188082-","C188083-","C188084-","A188085-","C188086-","A188087-","A188088-","A188089-","T188090-","A188091-","G188092-","A188093-","A188094-","T188095-","A188096-","T188097-","G188098-","T188099-","C188100-","A188101-","T188102-","T188103-","G188104-","T188105-","G188106-","A188107-","C188108-","T188109-","C188110-","G188111-","A188112-","A188113-","T188114-","A188115-","G188116-","T188117-","T188118-","A188119-","T188120-","C188121-","G188122-","T188123-","C188124-","T188125-","C188126-","C188127-","T188128-","T188129-","A188130-","A188131-","A188132-","G188133-","C188134-","T188135-","T188136-","C188137-","T188138-","G188139-","A188140-","T188141-","G188142-","G188143-","T188144-","A188145-","A188146-","C188147-","T188148-","G188149-","T188150-","G188151-","T188152-","T188153-","A188154-","C188155-","A188156-","T188157-","G188158-","T188159-","G188160-","C188161-","T188162-","C188163-","C188164-","T188165-","A188166-","A188167-","A188168-","A188169-","C188170-","A188171-","A188172-","A188173-","A188174-","T188175-","A188176-","T188177-","G188178-","G188179-","T188180-","C188181-","G188182-","T188183-","G188184-","T188185-","G188186-","T188187-","A188188-","C188189-","G188190-","G188191-","A188192-","A188193-","A188194-","G188195-","A188196-","A188197-","A188198-","G188199-","G188200-","A188201-","G188202-","A188203-","A188204-","A188205-","A188206-","T188207-","G188208-","A188209-","T188210-","A188211-","T188212-","G188213-","G188214-","A188215-","A188216-","T188217-","A188218-","C188219-","C188220-","A188221-","T188222-","T188223-","T188224-","G188225-","T188226-","A188227-","A188228-","G188229-","A188230-","A188231-","A188232-","T188233-","G188234-","T188235-","C188236-","G188237-","G188238-","A188239-","A188240-","G188241-","G188242-","G188243-","T188244-","A188245-","C188246-","T188247-","T188248-","A188249-","T188250-","T188251-","C188252-","A188253-","G188254-","A188255-","T188256-","A188257-","T188258-","T188259-","G188260-","T188261-","A188262-","T188263-","C188264-","T188265-","G188266-","A188267-","C188268-","T188269-","C188270-","T188271-","G188272-","A188273-","T188274-","C188275-","A188276-","A188277-","T188278-","G188279-","T188280-","A188281-","A188282-","A188283-","C188284-","C188285-","T188286-","A188287-","T188288-","G188289-","A188290-","C188291-","A188292-","A188293-","G188294-","A188295-","T188296-","A188297-","A188298-","G188299-","A188300-","C188301-","T188302-","T188303-","A188304-","C188305-","T188306-","C188307-","G188308-","C188309-","A188310-","T188311-","C188312-","T188313-","A188314-","C188315-","T188316-","G188317-","G188318-","A188319-","T188320-","A188321-","G188322-","A188323-","C188324-","A188325-","T188326-","A188327-","A188328-","A188329-","T188330-","A188331-","T188332-","C188333-","C188334-","T188335-","C188336-","C188337-","T188338-","C188339-","G188340-","T188341-","A188342-","A188343-","T188344-","A188345-","A188346-","T188347-","G188348-","A188349-","A188350-","A188351-","T188352-","A188353-","T188354-","A188355-","A188356-","T188357-","A188358-","T188359-","A188360-","C188361-","A188362-","C188363-","T188364-","A188365-","A188366-","T188367-","T188368-","A188369-","T188370-","T188371-","A188372-","A188373-","T188374-","A188375-","T188376-","C188377-","A188378-","A188379-","T188380-","C188381-","G188382-","A188383-","G188384-","T188385-","A188386-","T188387-","T188388-","A188389-","A188390-","C188391-","A188392-","T188393-","A188394-","T188395-","A188396-","A188397-","G188398-","T188399-","T188400-","A188401-","T188402-","T188403-","T188404-","T188405-","T188406-","A188407-","A188408-","A188409-","C188410-","C188411-","C188412-","C188413-","T188414-","T188415-","T188416-","T188417-","G188418-","G188419-","G188420-","T188421-","T188422-","C188423-","C188424-","G188425-","T188426-","C188427-","C188428-","T188429-","A188430-","A188431-","A188432-","C188433-","G188434-","G188435-","C188436-","G188437-","T188438-","T188439-","T188440-","C188441-","G188442-","G188443-","T188444-","C188445-","T188446-","G188447-","T188448-","G188449-","T188450-","C188451-","G188452-","C188453-","C188454-","A188455-","C188456-","C188457-","A188458-","T188459-","G188460-","G188461-","T188462-","C188463-","A188464-","C188465-","A188466-","C188467-","C188468-","G188469-","A188470-","G188471-","C188472-","C188473-","T188474-","C188475-","T188476-","G188477-","C188478-","G188479-","T188480-","G188481-","C188482-","T188483-","C188484-","C188485-","T188486-","C188487-","C188488-","A188489-","T188490-","C188491-","G188492-","A188493-","G188494-","G188495-","A188496-","C188497-","G188498-","A188499-","C188500-","T188501-","T188502-","C188503-","A188504-","A188505-","C188506-","T188507-","A188508-","T188509-","G188510-","A188511-","C188512-","A188513-","G188514-","C188515-","T188516-","C188517-","G188518-","G188519-","T188520-","G188521-","G188522-","C188523-","G188524-","T188525-","C188526-","T188527-","G188528-","C188529-","C188530-","A188531-","G188532-","C188533-","G188534-","T188535-","G188536-","T188537-","A188538-","C188539-","A188540-","T188541-","A188542-","C188543-","G188544-","A188545-","A188546-","T188547-","G188548-","G188549-","C188550-","A188551-","T188552-","T188553-","T188554-","C188555-","T188556-","A188557-","A188558-","G188559-","A188560-","A188561-","A188562-","A188563-","G188564-","T188565-","C188566-","T188567-","A188568-","C188569-","G188570-","G188571-","T188572-","A188573-","T188574-","C188575-","C188576-","T188577-","T188578-","T188579-","C188580-","T188581-","A188582-","C188583-","A188584-","A188585-","T188586-","T188587-","T188588-","C188589-","C188590-","T188591-","T188592-","T188593-","A188594-","A188595-","C188596-","A188597-","A188598-","C188599-","G188600-","G188601-","C188602-","A188603-","A188604-","C188605-","A188606-","G188607-","C188608-","T188609-","G188610-","C188611-","A188612-","G188613-","T188614-","A188615-","T188616-","T188617-","T188618-","T188619-","T188620-","A188621-","T188622-","A188623-","C188624-","T188625-","T188626-","T188627-","G188628-","A188629-","A188630-","T188631-","G188632-","C188633-","A188634-","T188635-","C188636-","G188637-","G188638-","A188639-","C188640-","A188641-","T188642-","T188643-","T188644-","A188645-","T188646-","A188647-","C188648-","A188649-","A188650-","G188651-","G188652-","G188653-","A188654-","G188655-","T188656-","C188657-","C188658-","T188659-","G188660-","T188661-","T188662-","C188663-","T188664-","A188665-","A188666-","T188667-","A188668-","T188669-","T188670-","G188671-","G188672-","C188673-","A188674-","T188675-","C188676-","A188677-","A188678-","T188679-","G188680-","T188681-","T188682-","C188683-","G188684-","G188685-","A188686-","T188687-","C188688-","T188689-","A188690-","T188691-","A188692-","G188693-","G188694-","C188695-","T188696-","T188697-","G188698-","A188699-","T188700-","T188701-","T188702-","T188703-","C188704-","G188705-","C188706-","A188707-","T188708-","T188709-","G188710-","A188711-","C188712-","T188713-","T188714-","T188715-","A188716-","C188717-","A188718-","C188719-","A188720-","G188721-","A188722-","C188723-","A188724-","T188725-","G188726-","A188727-","A188728-","C188729-","A188730-","T188731-","C188732-","C188733-","C188734-","C188735-","T188736-","G188737-","A188738-","A188739-","T188740-","C188741-","T188742-","G188743-","T188744-","A188745-","C188746-","A188747-","T188748-","A188749-","C188750-","T188751-","T188752-","T188753-","G188754-","T188755-","G188756-","G188757-","A188758-","T188759-","T188760-","T188761-","A188762-","C188763-","A188764-","C188765-","T188766-","G188767-","T188768-","T188769-","A188770-","G188771-","A188772-","A188773-","T188774-","C188775-","T188776-","C188777-","T188778-","A188779-","A188780-","C188781-","G188782-","C188783-","T188784-","G188785-","G188786-","C188787-","C188788-","T188789-","C188790-","T188791-","G188792-","T188793-","T188794-","G188795-","T188796-","T188797-","A188798-","C188799-","T188800-","T188801-","T188802-","C188803-","T188804-","A188805-","T188806-","G188807-","A188808-","T188809-","G188810-","C188811-","A188812-","C188813-","G188814-","T188815-","A188816-","T188817-","C188818-","G188819-","T188820-","T188821-","A188822-","T188823-","G188824-","C188825-","A188826-","A188827-","G188828-","C188829-","T188830-","T188831-","T188832-","C188833-","A188834-","T188835-","G188836-","T188837-","T188838-","G188839-","A188840-","C188841-","T188842-","A188843-","C188844-","T188845-","G188846-","C188847-","A188848-","G188849-","T188850-","G188851-","T188852-","T188853-","T188854-","C188855-","T188856-","T188857-","G188858-","C188859-","T188860-","C188861-","T188862-","G188863-","A188864-","C188865-","T188866-","A188867-","C188868-","A188869-","T188870-","A188871-","T188872-","A188873-","C188874-","T188875-","C188876-","T188877-","A188878-","C188879-","A188880-","A188881-","T188882-","C188883-","A188884-","A188885-","A188886-","G188887-","A188888-","G188889-","A188890-","G188891-","A188892-","T188893-","T188894-","T188895-","C188896-","A188897-","G188898-","T188899-","A188900-","A188901-","A188902-","C188903-","T188904-","T188905-","G188906-","T188907-","A188908-","A188909-","C188910-","A188911-","G188912-","G188913-","A188914-","T188915-","T188916-","G188917-","T188918-","T188919-","T188920-","G188921-","C188922-","T188923-","G188924-","C188925-","T188926-","T188927-","T188928-","C188929-","T188930-","G188931-","G188932-","A188933-","T188934-","-196616A"],"OPG023":["D392N"],"OPG057":["E353K"]},"labels":{"aa":"OPG023: D392N; OPG057: E353K"}}},{"name":"OP612688","node_attrs":{"div":28,"accession":"OP612688","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/104/19"},"date":{"value":"2019-11-02"},"strain_display":{"value":"Nigeria/OP612688/2019-11-02"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","G1126A","G2039A","G2152A","C6948T","C47224T","T76087-","C77726T","C143845T","G152431A","C166786T","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","G184037T","C184535T","C195058T","C195171T","C196084T"],"OPG002":["S238L"],"OPG002_dup":["S238L"],"OPG066":["E69K"],"OPG099":["S21F"],"OPG192":["S19L"]},"labels":{"aa":"OPG002: S238L; OPG002_dup: S238L; OPG066: E69K; OPG099: S21F; OPG192: S19L"}}},{"name":"OP612674","node_attrs":{"div":23,"accession":"OP612674","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/003/19"},"date":{"value":"2019-01-12"},"strain_display":{"value":"Nigeria/OP612674/2019-01-12"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C11555T","G28645A","G75967A","T76087-","G94840A","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","C188503T","A196612-","A196613-","A196614-","A196615-"],"OPG023":["R449Q"],"OPG115":["E61K"]},"labels":{"aa":"OPG023: R449Q; OPG115: E61K"}}},{"name":"NODE_0000028","node_attrs":{"div":19,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","G151929A","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","-196616A","-196617A"],"OPG178":["E141K"]},"labels":{"aa":"OPG178: E141K"}},"children":[{"name":"OL504742","node_attrs":{"div":26,"accession":"OL504742","author":{"author":"Atkinson,B.,Pottage,T.,Ngabo,D.,Crook,A.,Pitman,J.,Summers,S.,Pullan,S.,Lewandowski,K.,Furneaux,J.,Davies,K.,Brooks,T.","value":"Atkinson,B.,Pottage,T.,Ngabo,D.,Crook,A.,Pitman,J.,Summers,S.,Pullan,S.,Lewandowski,K.,Furneaux,J.,Davies,K.,Brooks,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research"},"lineage":{"value":"A.1"},"strain":{"value":"2095"},"date":{"value":"2019-12-XX"},"strain_display":{"value":"United Kingdom/OL504742/2019-12-XX"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["C13065T","C29887T","G61329A","C72206T","G103431A","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","C165369T","-173290A","-173291T","-173292A","-173293T","-173294A","-173295T","-173296A","-173300A","-173301T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G188949A","T192184C"],"OPG024":["G55E"],"OPG092":["E248K"],"OPG123":["S547L"],"OPG190":["S83F"]},"labels":{"aa":"OPG024: G55E; OPG092: E248K; OPG123: S547L; OPG190: S83F"}}},{"name":"OP612683","node_attrs":{"div":21,"accession":"OP612683","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/042/19"},"date":{"value":"2019-04-18"},"strain_display":{"value":"Nigeria/OP612683/2019-04-18"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-608T","T76087-","G81523A","C141757T"],"OPG105":["S133N"]},"labels":{"aa":"OPG105: S133N"}}},{"name":"NODE_0000029","node_attrs":{"div":20,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["C39767T"]}},"children":[{"name":"MT903342","node_attrs":{"div":22,"accession":"MT903342","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Singapore"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-Singapore"},"date":{"value":"2019-05-XX"},"strain_display":{"value":"Singapore/MT903342/2019-05-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-608T","C43927T","-146894A","-146895T","-146896A","-146897T","-146898T","-146899T","-146900T","-146901A","-146902T","-146903T","-146904T","-146905T","-146906A","-146907T","-146908A","-146909T","-146910T","-146911T","-146912T","C170573T","-173290A","-173291T","-173292A","-173293T","-173294A","-173295T","-173296A","-173297T","-173298A","-173299T","-173300A","-173301T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A196617-"],"OPG064":["E658K"],"OPG198":["S179L"]},"labels":{"aa":"OPG064: E658K; OPG198: S179L"}}},{"name":"OP612685","node_attrs":{"div":20,"accession":"OP612685","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/052/19"},"date":{"value":"2019-05-29"},"strain_display":{"value":"Nigeria/OP612685/2019-05-29"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-"]}}}]}]},{"name":"NODE_0000030","node_attrs":{"div":20,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["G25661A","C39119T","-173314A","-173315T","-173316A","-173317T"]}},"children":[{"name":"OP612679","node_attrs":{"div":28,"accession":"OP612679","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/018/19"},"date":{"value":"2019-03-14"},"strain_display":{"value":"Nigeria/OP612679/2019-03-14"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C8500T","G79538A","G81354A","G84416A","C88736T","G100642A","C138791T","C161616T","-196616A","-196617A"],"OPG102":["D152N"],"OPG105":["E77K"],"OPG109":["E238K"],"OPG119":["R86K"],"OPG156":["D207N"]},"labels":{"aa":"OPG102: D152N; OPG105: E77K; OPG109: E238K; OPG119: R86K; OPG156: D207N"}}},{"name":"NODE_0000031","node_attrs":{"div":21,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["T607-","G162243A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","A196615-"]}},"children":[{"name":"MT903345","node_attrs":{"div":21,"accession":"MT903345","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-UK_P3"},"date":{"value":"2018-09-XX"},"strain_display":{"value":"United Kingdom/MT903345/2018-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"MT903344","node_attrs":{"div":21,"accession":"MT903344","author":{"author":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y.","value":"Mauldin,M.R.,McCollum,A.M.,Nakazawa,Y.J.,Mandra,A.,Whitehouse,E.R.,Davidson,W.,Zhao,H.,Gao,J.,Li,Y.,Doty,J.,Yinka-Ogunleye,A.,Akinpelu,A.,Aruna,O.,Naidoo,D.,Lewandowski,K.,Afrough,B.,Graham,V.,Aarons,E.,Hewson,R.,Vipond,R.,Dunning,J.,Chand,M.,Brown,C.,Cohen-Gihon,I.,Erez,N.,Shifman,O.,Israeli,O.,Sharon,M.,Schwartz,E.,Beth-Din,A.,Zvi,A.,Mak,T.M.,Ng,Y.K.,Cui,L.,Lin,R.T.P.,Olson,V.A.,Brooks,T.,Paran,N.,Ihekweazu,C.,Reynolds,M.G.,Nakazawa,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Center for Emerging and Zoonotic Infectious Diseases, Division of High Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV-UK_P2"},"date":{"value":"2018-09-XX"},"strain_display":{"value":"United Kingdom/MT903344/2018-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"]}}},{"name":"NODE_0000032","node_attrs":{"div":24,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["G1262A","C3818T","G124130A","C128698T","T133102-","T133177-","C133178-","T133179-","T133180-","T133181-","C133182-","T133183-","C133184-","A133185-","A133186-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179177T","-179178A","G193392A","C195948T"],"OPG001":["S105L"],"OPG001_dup":["S105L"],"OPG003":["D264N"],"OPG003_dup":["D264N"],"OPG145":["E62K"],"OPG150":["S307L"]},"labels":{"aa":"OPG001: S105L; OPG001_dup: S105L; OPG003: D264N; OPG003_dup: D264N; OPG145: E62K; OPG150: S307L"}},"children":[{"name":"OP612687","node_attrs":{"div":29,"accession":"OP612687","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/058/19"},"date":{"value":"2019-07-11"},"strain_display":{"value":"Nigeria/OP612687/2019-07-11"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","C756T","G2039A","G168365A","A173288-","T173289-","-179172C","-179173A","-179174T","-179175T","-179176A","C188605A","A188606C","G188607A","T193455A","C195171T","G196454-","A196614-"],"OPG002":["S238L"],"OPG002_dup":["S238L"],"OPG003_dup":["L285I"],"OPG195":["E46K"]},"labels":{"aa":"OPG002: S238L; OPG002_dup: S238L; OPG003_dup: L285I; OPG195: E46K"}}},{"name":"NODE_0000033","node_attrs":{"div":25,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1"}},"branch_attrs":{"mutations":{"nuc":["G81275A"]}},"children":[{"name":"OP612686","node_attrs":{"div":26,"accession":"OP612686","author":{"author":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O.","value":"Ndodo,N.,Ashcroft,J.,Lewandowski,K.,Yinka-Ogunleye,A.,Chukwu,C.,Ahmad,A.,King,D.,Akinpelu,A.,Maluquer de Motes,C.,Ribeca,P.,Summer,R.P.,Rambaut,A.,Chester,M.,Maishman,T.,Babatunde,O.,Mba,N.,Aruna,O.,Pullan,S.T.,Gannon,B.,Brown,C.,Ihekweazu,C.,Adetifa,I.,Ulaeto,D.O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Nigeria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Defence Science and Technology Laboratory, Chemical, Biological and Radiological Sciences"},"lineage":{"value":"A.1"},"strain":{"value":"MPXV/053/19"},"date":{"value":"2019-06-26"},"strain_display":{"value":"Nigeria/OP612686/2019-06-26"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","T76087-","G88640A","-179172C","-179173A","-179174T","-179175T","-179176A","-196615A","-196616A","-196617A"],"OPG109":["R270C"]},"labels":{"aa":"OPG109: R270C"}}},{"name":"NODE_0000034","node_attrs":{"div":50,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"A.1.1"}},"branch_attrs":{"mutations":{"nuc":["G2591A","G3522A","C7771T","G14000T","G15428A","G21723A","G30367A","G31053A","G34459A","G37202A","G38360A","C38662T","G52885A","G54117A","G54635A","G64297A","C73066T","C82373T","G82451A","G95034A","G124674A","-133102T","C162331T","-173290A","-173291T","-173292A","-173293T","-173294A","-173295T","-173296A","-173297T","-173298A","-173299T","-173300A","-173301T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","G178133A","G181980A","G186578A","C193688T","C194619T"],"OPG002":["S54F"],"OPG002_dup":["S54F"],"OPG025":["A423D"],"OPG047":["R48C"],"OPG053":["P78S"],"OPG056":["E125K"],"OPG071":["L108F"],"OPG072":["D56N"],"OPG093":["S30L"],"OPG145":["R243Q"],"OPG210":["D209N","M1741I"]},"labels":{"aa":"OPG002: S54F; OPG002_dup: S54F; OPG025: A423D; OPG047: R48C; OPG053: P78S; OPG056: E125K; OPG071: L108F; OPG072: D56N; OPG093: S30L; OPG145: R243Q; OPG210: D209N, M1741I","clade":"A.1.1"}},"children":[{"name":"ON676708","node_attrs":{"div":53,"accession":"ON676708","author":{"author":"Gigante,C.M.,Myers,R.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Blythe,D.,Li,Y.","value":"Gigante,C.M.,Myers,R.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Blythe,D.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"A.1.1"},"strain":{"value":"MPXV_USA_2021_MD"},"date":{"value":"2021-11-XX"},"strain_display":{"value":"USA/ON676708/2021-11-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C79348T","C86979T","C133714T","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"NODE_0000035","node_attrs":{"div":61,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G3111A","C39139T","G73239A","G74205A","G77383A","C84587T","C150469T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A151461C","G155795A","G170262A","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C183519T","C194099T"],"OPG057":["E353K"],"OPG093":["D88N"],"OPG094":["M142I"],"OPG098":["E162K"],"OPG176":["H221Y"],"OPG210":["P722S"]},"labels":{"aa":"OPG057: E353K; OPG093: D88N; OPG094: M142I; OPG098: E162K; OPG176: H221Y; OPG210: P722S","clade":"B.1"}},"children":[{"name":"LC722946","node_attrs":{"div":64,"accession":"LC722946","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Japan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/TKY220091/2022"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Japan/LC722946/2022-07-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C13653T","C116100T","G150376A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG025":["D539N"],"OPG176":["D190N"]},"labels":{"aa":"OPG025: D539N; OPG176: D190N"}}},{"name":"OP160532","node_attrs":{"div":62,"accession":"OP160532","author":{"author":"Tutu van Furth AM,van der Kuip M,van Els AL,Fievez LC,van Rijckevorsel GG,van den Ouden A,Jonges M,Welkers MR,Welkers,M.,Jonges,M.","value":"Tutu van Furth AM,van der Kuip M,van Els AL,Fievez LC,van Rijckevorsel GG,van den Ouden A,Jonges M,Welkers MR,Welkers,M.,Jonges,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Netherlands"},"clade_membership":{"value":"IIb"},"institution":{"value":"Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Netherlands/NH-AUMC-0001/2022"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Netherlands/OP160532/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A148207T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G191845A","A196614-"],"OPG173":["E57D"]},"labels":{"aa":"OPG173: E57D"}}},{"name":"OP150926","node_attrs":{"div":61,"accession":"OP150926","author":{"author":"Gigante,C.,Goldoft,M.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Holshue,M.,Li,Y.","value":"Gigante,C.,Goldoft,M.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Holshue,M.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_USA_2022_PA001"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/OP150926/2022-05-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP120938","node_attrs":{"div":63,"accession":"OP120938","author":{"author":"Aja-Macaya,P.,Rumbo-Feal,S.,Poza,M.,Canizares,A.,Vallejo,J.A.,Bou,G.","value":"Aja-Macaya,P.,Rumbo-Feal,S.,Poza,M.,Canizares,A.,Vallejo,J.A.,Bou,G."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Spain"},"clade_membership":{"value":"IIb"},"institution":{"value":"Biomedical research institute (INIBIC), Microbiology"},"lineage":{"value":"B.1"},"strain":{"value":"MP03CHUAC"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Spain/OP120938/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C118421T","C142607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG136":["M389I"],"OPG163":["H136Y"]},"labels":{"aa":"OPG136: M389I; OPG163: H136Y"}}},{"name":"OP019275","node_attrs":{"div":64,"accession":"OP019275","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Austria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV/Austria/MUW1525179/2022"},"date":{"value":"2022-06-10"},"strain_display":{"value":"Austria/OP019275/2022-06-10"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","A107070C","C144546T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G190319A","-196615A","-196616A","-196617A"],"OPG166":["S50F"]},"labels":{"aa":"OPG166: S50F"}}},{"name":"OP062230","node_attrs":{"div":62,"accession":"OP062230","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Jolly,G.,Griffiths,E.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Jolly,G.,Griffiths,E.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3864/2022"},"date":{"value":"2022-06-22"},"strain_display":{"value":"Canada/OP062230/2022-06-22"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C57790T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG077":["R265K"]},"labels":{"aa":"OPG077: R265K"}}},{"name":"ON843164","node_attrs":{"div":61,"accession":"ON843164","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0037/2022"},"date":{"value":"2022-05-18"},"strain_display":{"value":"Portugal/ON843164/2022-05-18"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C133103T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON872184","node_attrs":{"div":66,"accession":"ON872184","author":{"author":"Fletcher,N.,Gonzalez,G.,Meredith,L.,Purves,K.,Carr,M.,Dean,J.,Keogan,B.,Crowley,B.,Lyons,F.,O'Reilly,S.,Gautier,V.,Mallon,P.,Gordon,S.,Connell,J.,De Gascun,C.F.","value":"Fletcher,N.,Gonzalez,G.,Meredith,L.,Purves,K.,Carr,M.,Dean,J.,Keogan,B.,Crowley,B.,Lyons,F.,O'Reilly,S.,Gautier,V.,Mallon,P.,Gordon,S.,Connell,J.,De Gascun,C.F."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Ireland"},"clade_membership":{"value":"IIb"},"institution":{"value":"University College Dublin, National Virus Reference Laboratory"},"lineage":{"value":"B.1"},"strain":{"value":"WA-2022"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Ireland/ON872184/2022-05-30"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T48785C","G49636A","C50017T","T72809C","G178541A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG068":["G479E"],"OPG069":["T11I"],"OPG092":["K47E"]},"labels":{"aa":"OPG068: G479E; OPG069: T11I; OPG092: K47E"}}},{"name":"ON838940","node_attrs":{"div":61,"accession":"ON838940","author":{"author":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J.","value":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Spain"},"clade_membership":{"value":"IIb"},"institution":{"value":"Hospital Universitario La Paz, Microbiology"},"lineage":{"value":"B.1"},"strain":{"value":"4061"},"date":{"value":"2022-05-20"},"strain_display":{"value":"Spain/ON838940/2022-05-20"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON803426","node_attrs":{"div":61,"accession":"ON803426","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2856/2022"},"date":{"value":"2022-05-19"},"strain_display":{"value":"Canada/ON803426/2022-05-19"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON745215","node_attrs":{"div":61,"accession":"ON745215","author":{"author":"Giombini,E.,Gruber,C.E.M.,Rueca,M.,Gramigna,G.,VIta,S.,Carletti,F.,D'Abramo,A.,Lapa,D.,Puro,V.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Specchiarello,E.,Vairo,F.,Vaia,F.,Garbuglia,A.R.,Nicastri,E.,Antinori,A.,GIrardi,E.,Maggi,F.","value":"Giombini,E.,Gruber,C.E.M.,Rueca,M.,Gramigna,G.,VIta,S.,Carletti,F.,D'Abramo,A.,Lapa,D.,Puro,V.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Specchiarello,E.,Vairo,F.,Vaia,F.,Garbuglia,A.R.,Nicastri,E.,Antinori,A.,GIrardi,E.,Maggi,F."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Italy"},"clade_membership":{"value":"IIb"},"institution":{"value":"INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology"},"lineage":{"value":"B.1"},"strain":{"value":"INMI-Pt2"},"date":{"value":"2022-05-19"},"strain_display":{"value":"Italy/ON745215/2022-05-19"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T591A","A592-","T593-","T595A","-607T","-608T","-609T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A"]}}},{"name":"ON751962","node_attrs":{"div":64,"accession":"ON751962","author":{"author":"Claro,I.M.,de Lima,E.L.,Romano,C.M.,Candido,D.S.,Lindoso,J.A.L.,Barra,L.A.C.,Borges,L.M.S.,Medeiros,L.A.,Tomishige,M.Y.S.,Ramundo,M.S.,Moutinho,T.,da Silva,A.J.D.,Rodrigues,C.C.M.,de Azevedo,L.C.F.,Villas-Boas,L.S.,da Silva,C.A.M.,Coletti,T.M.,O'Toole,A.,Quick,J.,Loman,N.,Rambaut,A.,Faria,N.R.,Figueiredo-Mello,C.,Sabino,E.C.","value":"Claro,I.M.,de Lima,E.L.,Romano,C.M.,Candido,D.S.,Lindoso,J.A.L.,Barra,L.A.C.,Borges,L.M.S.,Medeiros,L.A.,Tomishige,M.Y.S.,Ramundo,M.S.,Moutinho,T.,da Silva,A.J.D.,Rodrigues,C.C.M.,de Azevedo,L.C.F.,Villas-Boas,L.S.,da Silva,C.A.M.,Coletti,T.M.,O'Toole,A.,Quick,J.,Loman,N.,Rambaut,A.,Faria,N.R.,Figueiredo-Mello,C.,Sabino,E.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Brazil"},"clade_membership":{"value":"IIb"},"institution":{"value":"Imperial College London, School of Public Health"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/BR0001/2022"},"date":{"value":"2022-06-07"},"strain_display":{"value":"Brazil/ON751962/2022-06-07"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G10118A","C15004T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G169928A","G173575-","A173576-","G173577-","A173578-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG021":["E178K"],"OPG197":["D87N"]},"labels":{"aa":"OPG021: E178K; OPG197: D87N"}}},{"name":"ON682269","node_attrs":{"div":61,"accession":"ON682269","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/RKI07"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/ON682269/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON615424","node_attrs":{"div":63,"accession":"ON615424","author":{"author":"Oude Munnink,B.B.,Boter,M.,Wellers,B.,Molenkamp,R.,Sikkema,R.S.,Koopmans,M.","value":"Oude Munnink,B.B.,Boter,M.,Wellers,B.,Molenkamp,R.,Sikkema,R.S.,Koopmans,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Netherlands"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Virology, Erasmus Medical Centre, The Netherlands"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_2022_NL001"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Netherlands/ON615424/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155611A","G171003A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","G179362-","G179363-","-196615A"],"OPG199":["E6K"]},"labels":{"aa":"OPG199: E6K"}}},{"name":"OP341487","node_attrs":{"div":65,"accession":"OP341487","author":{"author":"Welkers,M.,Jonges,M.,de Regt,M.,Ooijevaar,R.,Wagemakers,A.","value":"Welkers,M.,Jonges,M.,de Regt,M.,Ooijevaar,R.,Wagemakers,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Netherlands"},"clade_membership":{"value":"IIb"},"institution":{"value":"Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Netherlands/NH-AUMC-0060/2022"},"date":{"value":"2022-08-05"},"strain_display":{"value":"Netherlands/OP341487/2022-08-05"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C96773T","C109432T","C114985T","C142356T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG117":["S242L"],"OPG129":["D525N"],"OPG133":["D238N"],"OPG163":["S52F"]},"labels":{"aa":"OPG117: S242L; OPG129: D525N; OPG133: D238N; OPG163: S52F"}}},{"name":"OP324484","node_attrs":{"div":62,"accession":"OP324484","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0169/2022"},"date":{"value":"2022-07-03"},"strain_display":{"value":"Portugal/OP324484/2022-07-03"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C11787T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG023":["D372N"]},"labels":{"aa":"OPG023: D372N"}}},{"name":"OP215246","node_attrs":{"div":62,"accession":"OP215246","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/RKI210"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP215246/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C174842T"],"OPG204":["S104F"]},"labels":{"aa":"OPG204: S104F"}}},{"name":"OP205115","node_attrs":{"div":62,"accession":"OP205115","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_UK_2022_9000157"},"date":{"value":"2022-07-07"},"strain_display":{"value":"United Kingdom/OP205115/2022-07-07"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C78232T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP205123","node_attrs":{"div":62,"accession":"OP205123","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_UK_2022_9000167"},"date":{"value":"2022-06-30"},"strain_display":{"value":"United Kingdom/OP205123/2022-06-30"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C99954T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP422343","node_attrs":{"div":63,"accession":"OP422343","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Austria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV/Austria/MUW1540386/2022"},"date":{"value":"2022-08-08"},"strain_display":{"value":"Austria/OP422343/2022-08-08"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C102355T","C113923T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG121":["S189L"],"OPG133":["D592N"]},"labels":{"aa":"OPG121: S189L; OPG133: D592N"}}},{"name":"OP422245","node_attrs":{"div":61,"accession":"OP422245","author":{"author":"Laubscher,F.,Chudzinsk,V.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinsk,V.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Switzerland"},"clade_membership":{"value":"IIb"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV-CH-38212023/2022"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Switzerland/OP422245/2022-05-30"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OP415223","node_attrs":{"div":65,"accession":"OP415223","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1"},"strain":{"value":"MPX_jpMpSR_9000252"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415223/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C23567T","C67289T","G67527A","G77052A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG085":["E415K"]},"labels":{"aa":"OPG085: E415K"}}},{"name":"OP415194","node_attrs":{"div":61,"accession":"OP415194","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1"},"strain":{"value":"MPX_96X1Vd_9000216"},"date":{"value":"2022-03-XX"},"strain_display":{"value":"United Kingdom/OP415194/2022-03-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP414305","node_attrs":{"div":62,"accession":"OP414305","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0265/2022"},"date":{"value":"2022-06-17"},"strain_display":{"value":"Portugal/OP414305/2022-06-17"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","G25030A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"],"OPG040":["S150F"]},"labels":{"aa":"OPG040: S150F"}}},{"name":"OP382484","node_attrs":{"div":61,"accession":"OP382484","author":{"author":"Colson,P.","value":"Colson,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV-IHU00007"},"date":{"value":"2022-07-06"},"strain_display":{"value":"France/OP382484/2022-07-06"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP382478","node_attrs":{"div":62,"accession":"OP382478","author":{"author":"Colson,P.","value":"Colson,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV-IHU00001"},"date":{"value":"2022-06-13"},"strain_display":{"value":"France/OP382478/2022-06-13"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C178006T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG205":["S784F"]},"labels":{"aa":"OPG205: S784F"}}},{"name":"OP536811","node_attrs":{"div":63,"accession":"OP536811","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1"},"strain":{"value":"9000448"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536811/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C95004T","G111541A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG130":["S121F"]},"labels":{"aa":"OPG130: S121F"}}},{"name":"OP494265","node_attrs":{"div":63,"accession":"OP494265","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI374"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP494265/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C141266T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A153679T","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG180":["T330S"]},"labels":{"aa":"OPG180: T330S"}}},{"name":"OP587248","node_attrs":{"div":61,"accession":"OP587248","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDPH, VRDL"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-CDPH-MPX000019/2022"},"date":{"value":"2022-07-08"},"strain_display":{"value":"USA/OP587248/2022-07-08"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP555660","node_attrs":{"div":63,"accession":"OP555660","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0593/2022"},"date":{"value":"2022-09-14"},"strain_display":{"value":"Portugal/OP555660/2022-09-14"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C55859T","C93755T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG074":["V423I"]},"labels":{"aa":"OPG074: V423I"}}},{"name":"OP555573","node_attrs":{"div":63,"accession":"OP555573","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox/PT0499/2022"},"date":{"value":"2022-08-12"},"strain_display":{"value":"Portugal/OP555573/2022-08-12"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G2985A","C58850T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C194225T"],"OPG079":["E258K"]},"labels":{"aa":"OPG079: E258K"}}},{"name":"OP879743","node_attrs":{"div":61,"accession":"OP879743","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"lineage":{"value":"B.1"},"strain":{"value":"NJ-MPXV-027"},"date":{"value":"2022-06-29"},"strain_display":{"value":"USA/OP879743/2022-06-29"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP715825","node_attrs":{"div":63,"accession":"OP715825","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/RKI545"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OP715825/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G28706A","C38873T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG045":["P186L"],"OPG056":["M54I"]},"labels":{"aa":"OPG045: P186L; OPG056: M54I"}}},{"name":"OP693649","node_attrs":{"div":63,"accession":"OP693649","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1"},"strain":{"value":"ANT_INS_MPX_0039_L"},"date":{"value":"2022-07-29"},"strain_display":{"value":"Colombia/OP693649/2022-07-29"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A2840-","T2841-","C2842-","G127058A","G136194A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","T196865-","A196866-","G196867-"],"OPG148":["R358K"],"OPG153":["H492Y"]},"labels":{"aa":"OPG148: R358K; OPG153: H492Y"}}},{"name":"OQ411312","node_attrs":{"div":62,"accession":"OQ411312","author":{"author":"Laubscher,F.,Chudzinsk,V.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinsk,V.,Schibler,M.,Kaiser,L.,Renzoni,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Switzerland"},"clade_membership":{"value":"IIb"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV-CH-38292866/2022"},"date":{"value":"2022-06-08"},"strain_display":{"value":"Switzerland/OQ411312/2022-06-08"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C87764T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG109":["E562K"]},"labels":{"aa":"OPG109: E562K"}}},{"name":"OQ557951","node_attrs":{"div":66,"accession":"OQ557951","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_USA_2022_TX0003"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ557951/2022-10-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","C19610T","G108050A","T133102-","C135024T","C135225T","C156627T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-196615A"]}}},{"name":"OQ547873","node_attrs":{"div":62,"accession":"OQ547873","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDPH, VRDL"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000155/2022"},"date":{"value":"2022-12-15"},"strain_display":{"value":"USA/OQ547873/2022-12-15"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T620-","T621-","T622-","T6976-","G102694A","A140155T","A140156G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG159":["N130C"]},"labels":{"aa":"OPG159: N130C"}}},{"name":"OR030937","node_attrs":{"div":62,"accession":"OR030937","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_26"},"date":{"value":"2022-07-19"},"strain_display":{"value":"Belgium/OR030937/2022-07-19"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T98627C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG118":["V61A"]},"labels":{"aa":"OPG118: V61A"}}},{"name":"OQ973326","node_attrs":{"div":65,"accession":"OQ973326","author":{"author":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L.","value":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"lineage":{"value":"B.1"},"strain":{"value":"case1_air"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Belgium/OQ973326/2022-09-01"},"region":{"value":"Europe"}},"branch_attrs":{"mutations":{"nuc":["T606-","G2615-","A2616-","T2617-","A2618-","G2619-","A2620-","C2621-","A2622-","A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","T2653-","T2654-","T2655-","A2656-","C2657-","A2658-","C2659-","T2660-","T2661-","C111391T","C119654T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","C152191T","A173314-","T173315-","A173316-","T173317-","C176178T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A194549-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","A196613-","A196614-"],"OPG002":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-"],"OPG002_dup":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-"],"OPG130":["C171Y"],"OPG137":["S18L"],"OPG205":["H175Y"]},"labels":{"aa":"OPG002: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-; OPG002_dup: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-; OPG130: C171Y; OPG137: S18L; OPG205: H175Y"}}},{"name":"OQ918696","node_attrs":{"div":67,"accession":"OQ918696","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00485/2023"},"date":{"value":"2023-03-11"},"strain_display":{"value":"USA/OQ918696/2023-03-11"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G30285A","G37487A","C71193T","G119839A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C161690T","C177865T","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T179244-"],"OPG047":["P304S"],"OPG137":["E80K"],"OPG188":["S32F"],"OPG205":["S737F"]},"labels":{"aa":"OPG047: P304S; OPG137: E80K; OPG188: S32F; OPG205: S737F"}}},{"name":"OQ644777","node_attrs":{"div":65,"accession":"OQ644777","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00471/2023"},"date":{"value":"2023-02-13"},"strain_display":{"value":"USA/OQ644777/2023-02-13"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G2146A","A24345G","C39044T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T170904-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T187876C","C195064T"]}}},{"name":"OQ581849","node_attrs":{"div":63,"accession":"OQ581849","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Spain"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0007b/2022"},"date":{"value":"2022-07-05"},"strain_display":{"value":"Spain/OQ581849/2022-07-05"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A52777C","C150418T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T169409C","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG071":["Y554*"]},"labels":{"aa":"OPG071: Y554*"}}},{"name":"OQ570421","node_attrs":{"div":63,"accession":"OQ570421","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Italy"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"lineage":{"value":"B.1"},"strain":{"value":"INMI-22872022"},"date":{"value":"2022-08-22"},"strain_display":{"value":"Italy/OQ570421/2022-08-22"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C106275T","G111562A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG130":["S114F"]},"labels":{"aa":"OPG130: S114F"}}},{"name":"OR264423","node_attrs":{"div":62,"accession":"OR264423","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1"},"strain":{"value":"46_C"},"date":{"value":"2022-07-13"},"strain_display":{"value":"Australia/OR264423/2022-07-13"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","A41657-","C41658-","T41659-","A41660-","A41661-","T41662-","T41663-","T41664-","G41665-","T41666-","T41667-","T41668-","T41669-","A41670-","C41671-","T41672-","C41673-","T41674-","A41675-","T41676-","A41677-","C118161T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG061":["V72-","K73-","Q74-","I75-","S76-","I77-","S78-"],"OPG136":["R476Q"]},"labels":{"aa":"OPG061: V72-, K73-, Q74-, I75-, S76-, I77-, S78-; OPG136: R476Q"}}},{"name":"OR264404","node_attrs":{"div":66,"accession":"OR264404","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1"},"strain":{"value":"39_D"},"date":{"value":"2022-05-19"},"strain_display":{"value":"Australia/OR264404/2022-05-19"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C21128T","A22452T","C66718T","C144356T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188683T"],"OPG037":["E436K"],"OPG084":["S666L"]},"labels":{"aa":"OPG037: E436K; OPG084: S666L"}}},{"name":"OR095046","node_attrs":{"div":62,"accession":"OR095046","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Van Holm,B.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Van Holm,B.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_228/Belgium/2022'"},"date":{"value":"2022-08-12"},"strain_display":{"value":"Belgium/OR095046/2022-08-12"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133100-","T133101-","T133102-","C147965T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C196881-","G196882-","T196883-"],"OPG172":["S180F"]},"labels":{"aa":"OPG172: S180F"}}},{"name":"OR759186","node_attrs":{"div":65,"accession":"OR759186","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Canada/ON-PHOL098/2022"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759186/2022-09-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C77462T","C111164T","A143676G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C152385T"],"OPG098":["S188F"],"OPG130":["E247K"],"OPG165":["N54S"]},"labels":{"aa":"OPG098: S188F; OPG130: E247K; OPG165: N54S"}}},{"name":"OR759167","node_attrs":{"div":61,"accession":"OR759167","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1"},"strain":{"value":"hMpxV/Canada/ON-PHOL079/2022"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759167/2022-08-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR035713","node_attrs":{"div":61,"accession":"OR035713","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_107"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035713/2022-10-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP205139","node_attrs":{"div":61,"accession":"OP205139","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_UK_2022_9000090"},"date":{"value":"2022-05-25"},"strain_display":{"value":"United Kingdom/OP205139/2022-05-25"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON631241","node_attrs":{"div":61,"accession":"ON631241","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia"},"lineage":{"value":"B.1"},"strain":{"value":"2022/2 SLO"},"date":{"value":"2022-05-24"},"strain_display":{"value":"Slovenia/ON631241/2022-05-24"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON782022","node_attrs":{"div":61,"accession":"ON782022","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.,Sironen,T.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.,Sironen,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Finland"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"lineage":{"value":"B.1"},"strain":{"value":"MPX-42/Finland/2022"},"date":{"value":"2022-05-31"},"strain_display":{"value":"Finland/ON782022/2022-05-31"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"ON649879","node_attrs":{"div":61,"accession":"ON649879","author":{"author":"Israeli,O.,Guedj-Dana,Y.,Lazar,S.,Shifman,O.,Erez,N.,Weiss,S.,Paran,N.,Israely,T.,Schuster,O.,Zvi,A.,Beth-Din,A.,Cohen Gihon,I.","value":"Israeli,O.,Guedj-Dana,Y.,Lazar,S.,Shifman,O.,Erez,N.,Weiss,S.,Paran,N.,Israely,T.,Schuster,O.,Zvi,A.,Beth-Din,A.,Cohen Gihon,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Israel"},"clade_membership":{"value":"IIb"},"institution":{"value":"Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_ISR001_2022"},"date":{"value":"2022-05-20"},"strain_display":{"value":"Israel/ON649879/2022-05-20"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OR035655","node_attrs":{"div":61,"accession":"OR035655","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_49"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Belgium/OR035655/2022-05-30"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON563414","node_attrs":{"div":61,"accession":"ON563414","author":{"author":"Gigante,C.M.,Smole,S.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Brown,C.,Li,Y.","value":"Gigante,C.M.,Smole,S.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Brown,C.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_USA_2022_MA001"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/ON563414/2022-05-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON755040","node_attrs":{"div":61,"accession":"ON755040","author":{"author":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O.","value":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"IRBA, D.DNRBC/D.2MI/U.BACT"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_IRBA22-14"},"date":{"value":"2022-05-20"},"strain_display":{"value":"France/ON755040/2022-05-20"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000036","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C156429T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP019277","node_attrs":{"div":64,"accession":"OP019277","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Austria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"lineage":{"value":"B.1"},"strain":{"value":"hMPXV/Austria/MUW1531254/2022"},"date":{"value":"2022-07-04"},"strain_display":{"value":"Austria/OP019277/2022-07-04"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G162265A","C165278T"],"OPG188":["E224K"],"OPG190":["H53Y"]},"labels":{"aa":"OPG188: E224K; OPG190: H53Y"}}},{"name":"OP270023","node_attrs":{"div":66,"accession":"OP270023","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3975/2022"},"date":{"value":"2022-07-04"},"strain_display":{"value":"Canada/OP270023/2022-07-04"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G40625A","C65571T","C134205T","G144988A","-196615A"]}}}]},{"name":"NODE_0000037","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["A87268G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG109":["V727A"]},"labels":{"aa":"OPG109: V727A"}},"children":[{"name":"ON929076","node_attrs":{"div":63,"accession":"ON929076","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/RKI121"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/ON929076/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C141757T"]}}},{"name":"OP689663","node_attrs":{"div":64,"accession":"OP689663","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI510"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"Germany/OP689663/2022-10-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G84579A","G115865A"],"OPG105":["D1152N"],"OPG134":["R39K"]},"labels":{"aa":"OPG105: D1152N; OPG134: R39K"}}}]},{"name":"NODE_0000038","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C36405T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG055":["A227T"]},"labels":{"aa":"OPG055: A227T"}},"children":[{"name":"OP837473","node_attrs":{"div":67,"accession":"OP837473","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1"},"strain":{"value":"VAC_INS_MPX_1054_L"},"date":{"value":"2022-10-25"},"strain_display":{"value":"Colombia/OP837473/2022-10-25"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C33082T","C40849T","G68103A","G117233A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C180361T","A197043-","T197044-","G197045-"],"OPG049":["D24N"],"OPG060":["E112K"]},"labels":{"aa":"OPG049: D24N; OPG060: E112K"}}},{"name":"OQ320447","node_attrs":{"div":65,"accession":"OQ320447","author":{"author":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y.","value":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV_USA_2022_DC0018"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ320447/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","C14226T","C46679T","C181816T","A196613-","A196614-"],"OPG025":["D348N"],"OPG210":["S154L"]},"labels":{"aa":"OPG025: D348N; OPG210: S154L"}}}]},{"name":"NODE_0000039","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C127215T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG149":["S7L"]},"labels":{"aa":"OPG149: S7L"}},"children":[{"name":"OQ148466","node_attrs":{"div":66,"accession":"OQ148466","author":{"author":"Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"lineage":{"value":"B.1"},"strain":{"value":"LBMB-UTP_MP-009_TOL"},"date":{"value":"2022-09-13"},"strain_display":{"value":"Colombia/OQ148466/2022-09-13"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G57907A","C105991T","C114157T","G175662A"],"OPG077":["S226L"],"OPG133":["E514K"],"OPG205":["E3K"]},"labels":{"aa":"OPG077: S226L; OPG133: E514K; OPG205: E3K"}}},{"name":"OR035705","node_attrs":{"div":63,"accession":"OR035705","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/UZ_REGA_99"},"date":{"value":"2022-06-02"},"strain_display":{"value":"Belgium/OR035705/2022-06-02"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C142797T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG164":["S7L"]},"labels":{"aa":"OPG164: S7L"}}}]},{"name":"NODE_0000040","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C53342T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG071":["R366K"]},"labels":{"aa":"OPG071: R366K"}},"children":[{"name":"OQ451902","node_attrs":{"div":67,"accession":"OQ451902","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2022/RKI717"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"Germany/OQ451902/2022-11-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","C3602T","C124495T","G159789A","C170573T","G190695A","G193608A"],"OPG003":["E336K"],"OPG003_dup":["E336K"],"OPG016":["E96K"],"OPG198":["S179L"]},"labels":{"aa":"OPG003: E336K; OPG003_dup: E336K; OPG016: E96K; OPG198: S179L"}}},{"name":"OQ331002","node_attrs":{"div":64,"accession":"OQ331002","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00374/2022"},"date":{"value":"2022-11-23"},"strain_display":{"value":"USA/OQ331002/2022-11-23"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C109535T","A136516-","T136517-","C156205T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196657-","T196658-","A196659-"]}}}]},{"name":"NODE_0000041","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G160358A"]}},"children":[{"name":"OQ503799","node_attrs":{"div":70,"accession":"OQ503799","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00411/2023"},"date":{"value":"2023-01-04"},"strain_display":{"value":"USA/OQ503799/2023-01-04"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G1512A","G12099A","G44107A","A60659T","G107064A","C143551T","G145790A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C188361T","C195698T"],"OPG001":["Q22*"],"OPG001_dup":["Q22*"],"OPG023":["R268*"],"OPG080":["F454I"]},"labels":{"aa":"OPG001: Q22*; OPG001_dup: Q22*; OPG023: R268*; OPG080: F454I"}}},{"name":"OQ721951","node_attrs":{"div":64,"accession":"OQ721951","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Taiwan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/human/Taiwan/110-122438/2023"},"date":{"value":"2023-03-XX"},"strain_display":{"value":"Taiwan/OQ721951/2023-03-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133092-","T133093-","T133094-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T149983A","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A184479G","G193496T","A193498T","A193748G","T194019G","T194021A","G194086A"],"OPG003_dup":["K298N","E299V","C473G","R495K"],"OPG176":["S59T"],"OPG210":["R1042G"]},"labels":{"aa":"OPG003_dup: K298N, E299V, C473G, R495K; OPG176: S59T; OPG210: R1042G"}}}]},{"name":"NODE_0000042","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T606-","G67955A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G184141A","A196614-"],"OPG085":["P193S"],"OPG210":["G929D"]},"labels":{"aa":"OPG085: P193S; OPG210: G929D"}},"children":[{"name":"OX291780","node_attrs":{"div":63,"accession":"OX291780","outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovakia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"lineage":{"value":"B.1"},"strain":{"value":"RNA"},"date":{"value":"2022-07-25"},"strain_display":{"value":"Slovakia/OX291780/2022-07-25"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A173316-","T173317-"]}}},{"name":"OX291676","node_attrs":{"div":64,"accession":"OX291676","outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovakia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"lineage":{"value":"B.1"},"strain":{"value":"RNA"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Slovakia/OX291676/2022-08-01"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G14590A","T133102-"]}}}]},{"name":"NODE_0000043","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C34784T","C101418T","G109844A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG054":["D405N"],"OPG120":["D111N"]},"labels":{"aa":"OPG054: D405N; OPG120: D111N"}},"children":[{"name":"OR743498","node_attrs":{"div":67,"accession":"OR743498","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1029"},"date":{"value":"2023-10-XX"},"strain_display":{"value":"Germany/OR743498/2023-10-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C45528T","C84767T","C170791T"],"OPG064":["R124K"]},"labels":{"aa":"OPG064: R124K"}}},{"name":"OR743494","node_attrs":{"div":64,"accession":"OR743494","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1025"},"date":{"value":"2023-09-XX"},"strain_display":{"value":"Germany/OR743494/2023-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G179263-","C179264-"]}}}]},{"name":"NODE_0000044","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G62109-","A62110-","T62111-","A62112-","A62113-","A62114-","G62115-","A62116-","G62117-","T62118-","C62119-","C62120-","T62121-","A62122-","T62123-","A62124-","T62125-","A62126-","T62127-","T62128-","T62129-","G62130-","A62131-","A62132-","A62133-","A62134-","T62135-","C62136-","G62137-","T62138-","T62139-","A62140-","C62141-","G62142-","G62143-","T62144-","T62145-","C62146-","G62147-","A62148-","T62149-","T62150-","A62151-","C62166-","A62167-","T62168-","T62169-","G62170-","T62171-","G62172-","A62173-","A62174-","T62175-","A62176-","T62177-","A62178-","T62179-","C62180-","A62181-","T62182-","T62183-","A62184-","G62185-","G62186-","A62187-","T62188-","T62189-","T62190-","A62191-","A62192-","C62193-","T62194-","C62195-","C62196-","T62197-","T62198-","G62199-","A62200-","C62201-","T62202-","A62203-","T62204-","C62205-","A62206-","T62207-","G62208-","G62209-","C62210-","G62211-","G62212-","T62213-","G62214-","C62215-","C62216-","A62217-","G62218-","A62219-","A62220-","A62221-","T62222-","T62223-","A62224-","C62225-","C62226-","A62227-","T62228-","C62229-","A62230-","A62231-","A62232-","A62233-","G62234-","C62235-","A62236-","T62237-","T62238-","A62239-","A62240-","T62241-","A62242-","C62243-","A62244-","G62245-","T62246-","T62247-","A62248-","T62249-","G62250-","C62251-","A62252-","G62253-","A62254-","T62255-","C62256-","G62257-","C62258-","A62259-","G62260-","T62261-","T62262-","A62263-","G62264-","A62265-","A62266-","C62267-","G62268-","G62269-","T62270-","T62271-","A62272-","T62273-","A62274-","G62275-","C62276-","A62277-","T62278-","C62279-","C62280-","A62281-","C62282-","C62283-","A62284-","T62285-","T62286-","T62287-","A62288-","T62289-","A62290-","T62291-","C62292-","T62293-","A62303-","T62304-","C62305-","A62306-","A62307-","A62308-","G62309-","A62310-","A62311-","T62312-","A62313-","T62314-","G62315-","T62316-","G62317-","A62318-","C62319-","A62320-","A62321-","C62322-","G62323-","T62324-","C62325-","C62326-","T62327-","A62328-","G62329-","T62330-","T62331-","G62332-","T62333-","A62334-","T62335-","A62336-","C62337-","T62338-","G62339-","A62340-","G62341-","A62342-","A62343-","T62344-","T62345-","G62346-","A62347-","C62348-","G62349-","A62350-","A62351-","A62352-","C62353-","A62354-","A62355-","T62356-","G62357-","C62376-","T62377-","T62378-","A62379-","T62380-","T62381-","A62382-","G62383-","T62384-","A62385-","A62386-","C62387-","C62388-","G62389-","A62390-","C62391-","T62392-","T62393-","A62394-","A62395-","T62396-","A62397-","G62398-","T62399-","A62400-","G62401-","G62402-","A62403-","A62404-","C62405-","T62406-","G62407-","G62408-","A62409-","A62410-","A62411-","A62412-","C62413-","T62414-","A62415-","G62416-","A62417-","C62418-","T62419-","T62420-","G62421-","A62422-","T62423-","T62424-","A62425-","T62426-","T62427-","C62428-","T62429-","A62430-","T62431-","A62432-","A62433-","G62434-","T62435-","A62436-","T62437-","A62438-","G62439-","A62440-","T62441-","A62442-","C62443-","C62444-","C62445-","T62446-","T62447-","C62448-","C62449-","A62450-","A62451-","A62452-","T62453-","A62454-","A62455-","T62456-","G62457-","T62458-","T62459-","C62460-","T62461-","C62462-","T62463-","T62464-","T62465-","G62466-","A62467-","T62468-","A62469-","A62470-","A62471-","A62472-","G62473-","T62474-","T62475-","C62476-","C62477-","A62478-","G62479-","A62480-","A62481-","A62482-","A62483-","T62484-","G62485-","T62486-","A62487-","G62488-","A62489-","A62490-","T62491-","T62492-","T62493-","T62494-","T62495-","T62496-","A62497-","A62498-","A62499-","A62500-","A62501-","G62502-","T62503-","T62504-","A62505-","T62506-","C62507-","T62508-","T62509-","T62510-","T62511-","G62512-","C62513-","T62514-","A62515-","T62516-","T62517-","A62518-","C62519-","T62520-","A62521-","A62522-","T62523-","A62524-","T62525-","C62526-","G62527-","T62528-","G62529-","G62530-","T62531-","T62532-","A62533-","G62534-","A62535-","C62536-","G62537-","C62538-","T62539-","T62540-","A62541-","T62542-","T62543-","A62544-","T62545-","T62546-","A62547-","A62548-","T62549-","A62550-","T62551-","G62552-","A62553-","G62554-","T62555-","G62556-","A62557-","T62558-","G62559-","A62560-","A62561-","A62562-","T62563-","C62564-","C62565-","A62566-","C62567-","A62568-","C62569-","C62570-","G62571-","C62572-","T62573-","T62574-","C62575-","T62576-","A62577-","G62578-","A62579-","T62580-","A62581-","T62582-","C62583-","G62584-","C62585-","T62586-","T62587-","T62588-","T62589-","A62590-","T62591-","T62592-","T62593-","C62594-","C62595-","A62596-","C62597-","A62598-","T62599-","T62600-","A62601-","G62602-","A62603-","T62604-","G62605-","G62606-","T62607-","A62608-","A62609-","A62610-","T62611-","C62612-","C62613-","A62614-","A62615-","T62616-","A62617-","G62618-","T62619-","G62620-","A62621-","A62622-","A62623-","C62624-","T62625-","A62626-","T62627-","C62628-","T62629-","T62630-","A62703-","T62704-","A62705-","A62706-","A62707-","C62708-","A62709-","A62710-","T62711-","T62712-","T62713-","C62714-","A62715-","C62716-","A62717-","A62718-","A62719-","T62720-","G62721-","G62722-","A62723-","T62724-","G62725-","T62726-","T62727-","A62728-","A62729-","T62730-","G62731-","T62732-","A62733-","T62734-","T62735-","A62736-","G62737-","T62738-","A62739-","G62740-","G62741-","A62742-","A62743-","A62744-","T62745-","T62746-","T62747-","T62748-","T62749-","T62750-","G62751-","A62752-","C62753-","G62754-","C62755-","T62756-","A62757-","G62758-","T62759-","G62760-","G62761-","A62762-","A62763-","T62764-","T62765-","G62766-","A62767-","A62768-","G62769-","A62770-","T62771-","T62772-","C62773-","T62774-","A62775-","A62776-","T62777-","G62778-","G62779-","A62780-","T62781-","G62782-","A62783-","T62784-","G62785-","T62786-","T62787-","C62788-","T62789-","A62790-","C62791-","C62792-","T62793-","A62794-","T62795-","T62796-","T62797-","C62798-","A62799-","T62800-","C62801-","C62802-","G62803-","A62804-","T62805-","A62806-","A62807-","C62808-","A62809-","T62810-","G62811-","T62812-","T62813-","A62814-","A62815-","T62816-","T62817-","T62818-","C62819-","C62820-","A62821-","A62822-","T62823-","A62824-","C62825-","C62826-","A62827-","A62828-","C62829-","G62830-","G62831-","T62832-","T62833-","T62834-","T62835-","A62836-","A62837-","T62838-","A62839-","T62840-","T62841-","T62842-","C62843-","G62844-","A62845-","T62846-","G62847-","A62848-","T62849-","A62850-","T62851-","A62852-","C62853-","G62854-","G62855-","T62856-","A62857-","G62858-","T62859-","C62860-","T62861-","C62862-","T62863-","C62864-","T62865-","T62866-","T62867-","C62868-","G62869-","G62870-","A62871-","C62872-","T62873-","T62874-","A62875-","T62876-","A62877-","T62878-","A62879-","G62880-","C62881-","T62882-","T62883-","A62884-","T62885-","T62886-","C62887-","C62888-","A62889-","C62890-","A62891-","A62892-","T62893-","A62894-","C62895-","G62896-","A62897-","G62898-","T62899-","C62900-","A62901-","T62902-","T62903-","A62904-","T62905-","A62906-","T62907-","A62908-","C62909-","T62910-","C62911-","C62912-","A62913-","A62914-","A62915-","A62916-","A62917-","A62918-","C62919-","A62920-","A62921-","A62922-","A62923-","T62924-","A62925-","A62926-","C62927-","T62928-","A62929-","G62930-","T62931-","A62932-","T62933-","A62934-","A62935-","A62936-","A62937-","T62938-","C62939-","T62940-","G62941-","T62942-","A62943-","T62944-","C62945-","G62946-","A62947-","A62948-","T62949-","G62950-","G62951-","G62952-","A62953-","A62954-","A62955-","A62956-","A62957-","C62958-","G62959-","A62960-","A62961-","A62962-","T62963-","T62964-","A62965-","T62966-","C62967-","G62968-","A62969-","T62970-","A62971-","T62972-","A62973-","G62974-","G62975-","T62976-","A62977-","T62978-","A62979-","G62980-","A62981-","A62982-","T62983-","C62984-","C62985-","G62986-","G62987-","A62988-","A62989-","C62990-","A62991-","T62992-","T62993-","G62994-","A62995-","A62996-","C62997-","G62998-","T62999-","A63000-","T63001-","T63002-","A63003-","A63004-","T63005-","A63006-","C63007-","T63008-","T63009-","A63010-","A63011-","T63012-","T63013-","C63014-","T63015-","T63016-","T63017-","T63018-","T63019-","C63020-","A63021-","G63022-","T63023-","G63024-","G63025-","T63026-","A63027-","A63028-","G63029-","A63030-","A63031-","C63032-","C63033-","G63034-","A63035-","T63036-","A63037-","G63038-","G63039-","T63040-","T63041-","A63042-","T63043-","T63044-","G63045-","A63046-","C63047-","A63048-","T63049-","T63050-","G63051-","T63052-","A63053-","T63054-","G63055-","G63056-","T63057-","T63058-","T63059-","T63060-","A63061-","A63062-","A63063-","T63064-","A63065-","T63066-","T63067-","C63068-","T63069-","A63070-","T63071-","A63072-","A63073-","C63074-","T63075-","T63076-","G63077-","A63078-","G63079-","A63080-","C63081-","T63082-","T63083-","G63084-","A63085-","T63086-","A63087-","G63088-","A63089-","T63090-","A63091-","T63092-","T63093-","A63094-","A63095-","T63096-","G63097-","A63098-","C63099-","G63100-","A63101-","A63102-","T63103-","T63104-","G63105-","A63106-","A63107-","A63108-","A63109-","T63110-","T63111-","A63112-","T63113-","T63114-","T63115-","T63116-","T63117-","A63118-","T63119-","C63120-","A63121-","C63122-","C63123-","A63124-","C63125-","G63126-","T63127-","G63128-","T63129-","G63130-","T63131-","T63132-","T63133-","C63134-","A63135-","G63136-","G63137-","A63138-","T63139-","C63140-","A63141-","T63142-","C63143-","G63144-","T63145-","C63146-","G63147-","A63148-","C63149-","G63150-","C63151-","C63152-","A63153-","G63154-","T63155-","T63156-","A63157-","A63158-","C63159-","C63160-","A63161-","A63162-","C63163-","C63164-","G63165-","A63166-","A63167-","T63168-","G63169-","G63170-","A63171-","G63172-","T63173-","A63174-","A63175-","A63176-","A63177-","T63178-","A63179-","A63180-","A63181-","T63182-","A63183-","T63184-","C63185-","A63186-","T63187-","T63188-","A63189-","A63190-","T63191-","A63192-","T63193-","A63194-","T63195-","G63196-","C63197-","T63198-","C63199-","T63200-","A63201-","G63202-","A63203-","T63204-","A63205-","T63206-","T63207-","A63208-","G63209-","T63210-","A63211-","T63212-","T63213-","T63214-","T63215-","T63216-","A63217-","T63218-","T63219-","A63220-","A63221-","T63222-","C63223-","C63224-","T63225-","T63226-","T63227-","G63228-","A63229-","T63230-","T63231-","A63232-","T63233-","C63234-","A63235-","T63236-","C63237-","T63238-","T63239-","C63240-","T63241-","C63242-","G63243-","T63244-","A63245-","C63246-","G63247-","C63248-","G63249-","A63250-","A63251-","T63252-","G63253-","A63254-","T63255-","T63256-","C63257-","C63258-","A63259-","T63260-","G63261-","A63262-","T63263-","C63264-","A63265-","A63266-","G63267-","A63268-","G63269-","T63270-","G63271-","A63272-","T63273-","T63274-","T63275-","G63276-","A63277-","G63278-","A63279-","A63280-","C63281-","A63282-","T63283-","C63284-","C63285-","T63286-","C63287-","C63288-","G63289-","G63290-","A63291-","G63292-","T63293-","A63294-","T63295-","T63296-","A63297-","A63298-","T63299-","G63300-","G63301-","G63302-","T63303-","T63304-","T63305-","A63306-","G63307-","T63308-","A63309-","A63310-","A63311-","C63312-","A63313-","G63314-","T63315-","C63316-","C63317-","A63318-","T63319-","C63320-","G63321-","T63322-","T63323-","G63324-","C63325-","A63326-","A63327-","T63328-","A63329-","A63330-","T63331-","A63332-","A63333-","A63334-","A63335-","G63336-","T63337-","T63338-","G63339-","T63340-","C63341-","C63342-","A63343-","A63344-","G63345-","T63346-","T63347-","A63348-","A63349-","A63350-","G63351-","G63352-","A63353-","T63354-","A63355-","T63356-","T63357-","A63358-","T63359-","G63360-","C63361-","A63362-","T63363-","T63364-","C63365-","G63366-","T63367-","T63368-","T63369-","A63370-","A63371-","A63372-","G63373-","A63374-","T63375-","A63376-","T63377-","C63378-","A63379-","C63380-","C63381-","T63382-","C63383-","A63384-","T63385-","C63386-","T63387-","A63388-","A63389-","C63390-","G63391-","G63392-","A63393-","G63394-","A63395-","C63396-","A63397-","A63398-","T63399-","T63400-","T63401-","T63402-","T63403-","T63404-","G63405-","G63406-","T63407-","A63408-","G63409-","G63410-","T63411-","T63412-","T63413-","T63414-","A63415-","G63416-","A63417-","G63418-","A63419-","C63420-","T63421-","T63422-","T63423-","G63424-","A63425-","A63426-","G63427-","C63428-","T63429-","A63430-","C63431-","T63432-","T63433-","G63434-","T63435-","T63436-","T63437-","A63438-","A63439-","C63440-","A63441-","A63442-","A63443-","G63444-","T63445-","T63446-","A63447-","T63448-","T63449-","C63450-","A63451-","T63452-","C63453-","G63454-","T63455-","C63456-","G63457-","T63458-","C63459-","T63460-","A63461-","C63462-","T63463-","A63464-","T63465-","T63466-","C63467-","T63468-","A63469-","T63470-","T63471-","T63472-","A63473-","A63474-","T63475-","T63476-","T63477-","T63478-","G63479-","T63480-","A63481-","G63482-","T63483-","T63484-","A63485-","A63486-","T63487-","T63488-","T63489-","A63490-","T63491-","C63492-","A63493-","C63494-","A63495-","T63496-","A63497-","T63498-","C63499-","A63500-","C63501-","A63502-","T63503-","T63504-","C89166T","C112408T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG131":["L157F"]},"labels":{"aa":"OPG131: L157F"}},"children":[{"name":"OQ672570","node_attrs":{"div":63,"accession":"OQ672570","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"lineage":{"value":"B.1"},"strain":{"value":"02112022_anal"},"date":{"value":"2022-11-02"},"strain_display":{"value":"Belgium/OQ672570/2022-11-02"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G47746-","G49680-","G49710-","A62294-","A62295-","A62296-","A62297-","A62298-","T62299-","T62300-","A62301-","G62302-","T62358-","T62359-","T62360-","C62361-","T62362-","T62363-","A62364-","C62365-","A62366-","T62367-","A62368-","T62369-","T62370-","T62371-","T62372-","T62373-","T62374-","T62375-"],"OPG068":["D494-"],"OPG081":["N46-","R47-","T48-","V49-","T50-","I51-","F52-","K53-","Y54-","I55-","G56-","L57-","F58-","I59-"]},"labels":{"aa":"OPG068: D494-; OPG081: N46-, R47-, T48-, V49-, T50-, I51-, F52-, K53-, Y54-, I55-, G56-, L57-, F58-, I59-"}}},{"name":"NODE_0000045","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","G187391A","A194549-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-"],"OPG002":["R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-","C47-"],"OPG002_dup":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-"]},"labels":{"aa":"OPG002: R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-, C47-; OPG002_dup: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-"}},"children":[{"name":"OQ672572","node_attrs":{"div":64,"accession":"OQ672572","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"lineage":{"value":"B.1"},"strain":{"value":"26012023_anal"},"date":{"value":"2023-01-26"},"strain_display":{"value":"Belgium/OQ672572/2023-01-26"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-62109G","-62110A","-62111T","-62112A","-62113A","-62114A","-62115G","-62116A","-62117G","-62118T","-62119C","-62120C","-62121T","-62122A","-62123T","-62124A","-62125T","-62126A","-62127T","-62128T","-62129T","-62130G","-62131A","-62132A","-62133A","-62134A","-62135T","-62136C","-62137G","-62138T","-62139T","-62140A","-62141C","-62142G","-62143G","-62144T","-62145T","-62146C","-62147G","-62148A","-62149T","-62150T","-62151A","-62166C","-62167A","-62168T","-62169T","-62170G","-62171T","-62172G","-62173A","-62174A","-62175T","-62176A","-62177T","-62178A","-62179T","-62180C","-62181A","-62182T","-62183T","-62184A","-62185G","-62186G","-62187A","-62188T","-62189T","-62190T","-62191A","-62192A","-62193C","-62194T","-62195C","-62196C","-62197T","-62198T","-62199G","-62200A","-62201C","-62202T","-62203A","-62204T","-62205C","-62206A","-62207T","-62208G","-62209G","-62210C","-62211G","-62212G","-62213T","-62214G","-62215C","-62216C","-62217A","-62218G","-62219A","-62220A","-62221A","-62222T","-62223T","-62224A","-62225C","-62226C","-62227A","-62228T","-62229C","-62230A","-62231A","-62232A","-62233A","-62234G","-62235C","-62236A","-62237T","-62238T","-62239A","-62240A","-62241T","-62242A","-62243C","-62244A","-62245G","-62246T","-62247T","-62248A","-62249T","-62250G","-62251C","-62252A","-62253G","-62254A","-62255T","-62256C","-62257G","-62258C","-62259A","-62260G","-62261T","-62262T","-62263A","-62264G","-62265A","-62266A","-62267C","-62268G","-62269G","-62270T","-62271T","-62272A","-62273T","-62274A","-62275G","-62276C","-62277A","-62278T","-62279C","-62280C","-62281A","-62282C","-62283C","-62284A","-62285T","-62286T","-62287T","-62288A","-62289T","-62290A","-62291T","-62292C","-62293T","-62303A","-62304T","-62305C","-62306A","-62307A","-62308A","-62309G","-62310A","-62311A","-62312T","-62313A","-62314T","-62315G","-62316T","-62317G","-62318A","-62319C","-62320A","-62321A","-62322C","-62323G","-62324T","-62325C","-62326C","-62327T","-62328A","-62329G","-62330T","-62331T","-62332G","-62333T","-62334A","-62335T","-62336A","-62337C","-62338T","-62339G","-62340A","-62341G","-62342A","-62343A","-62344T","-62345T","-62346G","-62347A","-62348C","-62349G","-62350A","-62351A","-62352A","-62353C","-62354A","-62355A","-62356T","-62357G","-62376C","-62377T","-62378T","-62379A","-62380T","-62381T","-62382A","-62383G","-62384T","-62385A","-62386A","-62387C","-62388C","-62389G","-62390A","-62391C","-62392T","-62393T","-62394A","-62395A","-62396T","-62397A","-62398G","-62399T","-62400A","-62401G","-62402G","-62403A","-62404A","-62405C","-62406T","-62407G","-62408G","-62409A","-62410A","-62411A","-62412A","-62413C","-62414T","-62415A","-62416G","-62417A","-62418C","-62419T","-62420T","-62421G","-62422A","-62423T","-62424T","-62425A","-62426T","-62427T","-62428C","-62429T","-62430A","-62431T","-62432A","-62433A","-62434G","-62435T","-62436A","-62437T","-62438A","-62439G","-62440A","-62441T","-62442A","-62443C","-62444C","-62445C","-62446T","-62447T","-62448C","-62449C","-62450A","-62451A","-62452A","-62453T","-62454A","-62455A","-62456T","-62457G","-62458T","-62459T","-62460C","-62461T","-62462C","-62463T","-62464T","-62465T","-62466G","-62467A","-62468T","-62469A","-62470A","-62471A","-62472A","-62473G","-62474T","-62475T","-62476C","-62477C","-62478A","-62479G","-62480A","-62481A","-62482A","-62483A","-62484T","-62485G","-62486T","-62487A","-62488G","-62489A","-62490A","-62491T","-62492T","-62493T","-62494T","-62495T","-62496T","-62497A","-62498A","-62499A","-62500A","-62501A","-62502G","-62503T","-62504T","-62505A","-62506T","-62507C","-62508T","-62509T","-62510T","-62511T","-62512G","-62513C","-62514T","-62515A","-62516T","-62517T","-62518A","-62519C","-62520T","-62521A","-62522A","-62523T","-62524A","-62525T","-62526C","-62527G","-62528T","-62529G","-62530G","-62531T","-62532T","-62533A","-62534G","-62535A","-62536C","-62537G","-62538C","-62539T","-62540T","-62541A","-62542T","-62543T","-62544A","-62545T","-62546T","-62547A","-62548A","-62549T","-62550A","-62551T","-62552G","-62553A","-62554G","-62555T","-62556G","-62557A","-62558T","-62559G","-62560A","-62561A","-62562A","-62563T","-62564C","-62565C","-62566A","-62567C","-62568A","-62569C","-62570C","-62571G","-62572C","-62573T","-62574T","-62575C","-62576T","-62577A","-62578G","-62579A","-62580T","-62581A","-62582T","-62583C","-62584G","-62585C","-62586T","-62587T","-62588T","-62589T","-62590A","-62591T","-62592T","-62593T","-62594C","-62595C","-62596A","-62597C","-62598A","-62599T","-62600T","-62601A","-62602G","-62603A","-62604T","-62605G","-62606G","-62607T","-62608A","-62609A","-62610A","-62611T","-62612C","-62613C","-62614A","-62615A","-62616T","-62617A","-62618G","-62619T","-62620G","-62621A","-62622A","-62623A","-62624C","-62625T","-62626A","-62627T","-62628C","-62629T","-62630T","-62703A","-62704T","-62705A","-62706A","-62707A","-62708C","-62709A","-62710A","-62711T","-62712T","-62713T","-62714C","-62715A","-62716C","-62717A","-62718A","-62719A","-62720T","-62721G","-62722G","-62723A","-62724T","-62725G","-62726T","-62727T","-62728A","-62729A","-62730T","-62731G","-62732T","-62733A","-62734T","-62735T","-62736A","-62737G","-62738T","-62739A","-62740G","-62741G","-62742A","-62743A","-62744A","-62745T","-62746T","-62747T","-62748T","-62749T","-62750T","-62751G","-62752A","-62753C","-62754G","-62755C","-62756T","-62757A","-62758G","-62759T","-62760G","-62761G","-62762A","-62763A","-62764T","-62765T","-62766G","-62767A","-62768A","-62769G","-62770A","-62771T","-62772T","-62773C","-62774T","-62775A","-62776A","-62777T","-62778G","-62779G","-62780A","-62781T","-62782G","-62783A","-62784T","-62785G","-62786T","-62787T","-62788C","-62789T","-62790A","-62791C","-62792C","-62793T","-62794A","-62795T","-62796T","-62797T","-62798C","-62799A","-62800T","-62801C","-62802C","-62803G","-62804A","-62805T","-62806A","-62807A","-62808C","-62809A","-62810T","-62811G","-62812T","-62813T","-62814A","-62815A","-62816T","-62817T","-62818T","-62819C","-62820C","-62821A","-62822A","-62823T","-62824A","-62825C","-62826C","-62827A","-62828A","-62829C","-62830G","-62831G","-62832T","-62833T","-62834T","-62835T","-62836A","-62837A","-62838T","-62839A","-62840T","-62841T","-62842T","-62843C","-62844G","-62845A","-62846T","-62847G","-62848A","-62849T","-62850A","-62851T","-62852A","-62853C","-62854G","-62855G","-62856T","-62857A","-62858G","-62859T","-62860C","-62861T","-62862C","-62863T","-62864C","-62865T","-62866T","-62867T","-62868C","-62869G","-62870G","-62871A","-62872C","-62873T","-62874T","-62875A","-62876T","-62877A","-62878T","-62879A","-62880G","-62881C","-62882T","-62883T","-62884A","-62885T","-62886T","-62887C","-62888C","-62889A","-62890C","-62891A","-62892A","-62893T","-62894A","-62895C","-62896G","-62897A","-62898G","-62899T","-62900C","-62901A","-62902T","-62903T","-62904A","-62905T","-62906A","-62907T","-62908A","-62909C","-62910T","-62911C","-62912C","-62913A","-62914A","-62915A","-62916A","-62917A","-62918A","-62919C","-62920A","-62921A","-62922A","-62923A","-62924T","-62925A","-62926A","-62927C","-62928T","-62929A","-62930G","-62931T","-62932A","-62933T","-62934A","-62935A","-62936A","-62937A","-62938T","-62939C","-62940T","-62941G","-62942T","-62943A","-62944T","-62945C","-62946G","-62947A","-62948A","-62949T","-62950G","-62951G","-62952G","-62953A","-62954A","-62955A","-62956A","-62957A","-62958C","-62959G","-62960A","-62961A","-62962A","-62963T","-62964T","-62965A","-62966T","-62967C","-62968G","-62969A","-62970T","-62971A","-62972T","-62973A","-62974G","-62975G","-62976T","-62977A","-62978T","-62979A","-62980G","-62981A","-62982A","-62983T","-62984C","-62985C","-62986G","-62987G","-62988A","-62989A","-62990C","-62991A","-62992T","-62993T","-62994G","-62995A","-62996A","-62997C","-62998G","-62999T","-63000A","-63001T","-63002T","-63003A","-63004A","-63005T","-63006A","-63007C","-63008T","-63009T","-63010A","-63011A","-63012T","-63013T","-63014C","-63015T","-63016T","-63017T","-63018T","-63019T","-63020C","-63021A","-63022G","-63023T","-63024G","-63025G","-63026T","-63027A","-63028A","-63029G","-63030A","-63031A","-63032C","-63033C","-63034G","-63035A","-63036T","-63037A","-63038G","-63039G","-63040T","-63041T","-63042A","-63043T","-63044T","-63045G","-63046A","-63047C","-63048A","-63049T","-63050T","-63051G","-63052T","-63053A","-63054T","-63055G","-63056G","-63057T","-63058T","-63059T","-63060T","-63061A","-63062A","-63063A","-63064T","-63065A","-63066T","-63067T","-63068C","-63069T","-63070A","-63071T","-63072A","-63073A","-63074C","-63075T","-63076T","-63077G","-63078A","-63079G","-63080A","-63081C","-63082T","-63083T","-63084G","-63085A","-63086T","-63087A","-63088G","-63089A","-63090T","-63091A","-63092T","-63093T","-63094A","-63095A","-63096T","-63097G","-63098A","-63099C","-63100G","-63101A","-63102A","-63103T","-63104T","-63105G","-63106A","-63107A","-63108A","-63109A","-63110T","-63111T","-63112A","-63113T","-63114T","-63115T","-63116T","-63117T","-63118A","-63119T","-63120C","-63121A","-63122C","-63123C","-63124A","-63125C","-63126G","-63127T","-63128G","-63129T","-63130G","-63131T","-63132T","-63133T","-63134C","-63135A","-63136G","-63137G","-63138A","-63139T","-63140C","-63141A","-63142T","-63143C","-63144G","-63145T","-63146C","-63147G","-63148A","-63149C","-63150G","-63151C","-63152C","-63153A","-63154G","-63155T","-63156T","-63157A","-63158A","-63159C","-63160C","-63161A","-63162A","-63163C","-63164C","-63165G","-63166A","-63167A","-63168T","-63169G","-63170G","-63171A","-63172G","-63173T","-63174A","-63175A","-63176A","-63177A","-63178T","-63179A","-63180A","-63181A","-63182T","-63183A","-63184T","-63185C","-63186A","-63187T","-63188T","-63189A","-63190A","-63191T","-63192A","-63193T","-63194A","-63195T","-63196G","-63197C","-63198T","-63199C","-63200T","-63201A","-63202G","-63203A","-63204T","-63205A","-63206T","-63207T","-63208A","-63209G","-63210T","-63211A","-63212T","-63213T","-63214T","-63215T","-63216T","-63217A","-63218T","-63219T","-63220A","-63221A","-63222T","-63223C","-63224C","-63225T","-63226T","-63227T","-63228G","-63229A","-63230T","-63231T","-63232A","-63233T","-63234C","-63235A","-63236T","-63237C","-63238T","-63239T","-63240C","-63241T","-63242C","-63243G","-63244T","-63245A","-63246C","-63247G","-63248C","-63249G","-63250A","-63251A","-63252T","-63253G","-63254A","-63255T","-63256T","-63257C","-63258C","-63259A","-63260T","-63261G","-63262A","-63263T","-63264C","-63265A","-63266A","-63267G","-63268A","-63269G","-63270T","-63271G","-63272A","-63273T","-63274T","-63275T","-63276G","-63277A","-63278G","-63279A","-63280A","-63281C","-63282A","-63283T","-63284C","-63285C","-63286T","-63287C","-63288C","-63289G","-63290G","-63291A","-63292G","-63293T","-63294A","-63295T","-63296T","-63297A","-63298A","-63299T","-63300G","-63301G","-63302G","-63303T","-63304T","-63305T","-63306A","-63307G","-63308T","-63309A","-63310A","-63311A","-63312C","-63313A","-63314G","-63315T","-63316C","-63317C","-63318A","-63319T","-63320C","-63321G","-63322T","-63323T","-63324G","-63325C","-63326A","-63327A","-63328T","-63329A","-63330A","-63331T","-63332A","-63333A","-63334A","-63335A","-63336G","-63337T","-63338T","-63339G","-63340T","-63341C","-63342C","-63343A","-63344A","-63345G","-63346T","-63347T","-63348A","-63349A","-63350A","-63351G","-63352G","-63353A","-63354T","-63355A","-63356T","-63357T","-63358A","-63359T","-63360G","-63361C","-63362A","-63363T","-63364T","-63365C","-63366G","-63367T","-63368T","-63369T","-63370A","-63371A","-63372A","-63373G","-63374A","-63375T","-63376A","-63377T","-63378C","-63379A","-63380C","-63381C","-63382T","-63383C","-63384A","-63385T","-63386C","-63387T","-63388A","-63389A","-63390C","-63391G","-63392G","-63393A","-63394G","-63395A","-63396C","-63397A","-63398A","-63399T","-63400T","-63401T","-63402T","-63403T","-63404T","-63405G","-63406G","-63407T","-63408A","-63409G","-63410G","-63411T","-63412T","-63413T","-63414T","-63415A","-63416G","-63417A","-63418G","-63419A","-63420C","-63421T","-63422T","-63423T","-63424G","-63425A","-63426A","-63427G","-63428C","-63429T","-63430A","-63431C","-63432T","-63433T","-63434G","-63435T","-63436T","-63437T","-63438A","-63439A","-63440C","-63441A","-63442A","-63443A","-63444G","-63445T","-63446T","-63447A","-63448T","-63449T","-63450C","-63451A","-63452T","-63453C","-63454G","-63455T","-63456C","-63457G","-63458T","-63459C","-63460T","-63461A","-63462C","-63463T","-63464A","-63465T","-63466T","-63467C","-63468T","-63469A","-63470T","-63471T","-63472T","-63473A","-63474A","-63475T","-63476T","-63477T","-63478T","-63479G","-63480T","-63481A","-63482G","-63483T","-63484T","-63485A","-63486A","-63487T","-63488T","-63489T","-63490A","-63491T","-63492C","-63493A","-63494C","-63495A","-63496T","-63497A","-63498T","-63499C","-63500A","-63501C","-63502A","-63503T","-63504T"]}}},{"name":"OQ672579","node_attrs":{"div":67,"accession":"OQ672579","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"lineage":{"value":"B.1"},"strain":{"value":"28022023_anal"},"date":{"value":"2023-02-28"},"strain_display":{"value":"Belgium/OQ672579/2023-02-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A2611-","C2612-","A2613-","C2614-","G2615-","A2616-","T2617-","A2618-","G2619-","A2620-","C2621-","A2622-","T2653-","T2654-","T2655-","A2656-","C2657-","A2658-","C2659-","T2660-","T2661-","T39397C","A48200-","A48201-","T48202-","G48203-","G48204-","A48205-","T48206-","T48207-","T48208-","T48209-","A48210-","T48211-","T48212-","C48213-","G48214-","T48215-","A48216-","G48217-","A48218-","A48219-","A48220-","G48221-","T48222-","A48223-","T48224-","C48225-","T48226-","T48227-","A48228-","T48229-","A48230-","T48231-","A48232-","C48233-","A48234-","C48235-","A48236-","G48237-","T48238-","A48239-","G48240-","A48241-","A48242-","A48243-","A48244-","T48245-","A48246-","A48247-","T48248-","A48249-","T48250-","A48251-","G48252-","A48253-","T48254-","T48255-","T48256-","T48257-","T48258-","T48259-","A48260-","A48261-","A48262-","G48263-","G48264-","A48265-","T48266-","G48267-","A48268-","T48269-","A48270-","C48271-","A48272-","T48273-","T48274-","A48275-","A48276-","G48277-","T48278-","A48279-","A48280-","A48281-","G48282-","T48283-","A48284-","A48285-","A48286-","C48287-","A48288-","A48289-","T48290-","T48291-","T48292-","T48293-","A48294-","C48295-","C48296-","C48297-","T48298-","C48299-","A48300-","A48301-","T48302-","C48303-","A48304-","T48305-","G48306-","T48307-","A48308-","C48309-","T48310-","A48311-","G48312-","C48313-","T48314-","C48315-","T48316-","C48317-","A48318-","A48319-","G48320-","T48321-","A48322-","T48323-","C48324-","T48325-","A48326-","G48327-","T48328-","T48329-","A48330-","G48331-","C48332-","A48333-","A48334-","T48335-","T48336-","T48337-","T48338-","C48339-","C48340-","T48341-","C48342-","A48343-","A48344-","C48345-","A48346-","T48347-","G48348-","T48349-","T48350-","A48351-","T48352-","T48353-","A48354-","C48355-","T48356-","A48357-","A48358-","G48359-","G48360-","A48361-","T48362-","G48363-","T48364-","A48365-","T48366-","T48367-","A48368-","G48369-","C48370-","T48371-","A48372-","A48373-","T48374-","A48375-","C48376-","C48377-","A48378-","A48379-","T48380-","T48381-","T48382-","T48383-","T48384-","T48385-","T48386-","G48387-","T48388-","T48389-","T48390-","T48391-","C48392-","A48393-","T48394-","A48395-","C48396-","A48397-","T48398-","A48399-","T48400-","G48401-","G48402-","T48403-","A48404-","C48405-","G48406-","A48407-","T48408-","G48409-","C48410-","T48411-","G48412-","T48413-","A48414-","A48415-","A48416-","G48417-","T48418-","A48419-","T48420-","A48421-","C48422-","G48423-","A48424-","A48425-","G48426-","C48427-","G48428-","G48429-","T48430-","T48431-","T48432-","T48433-","A48434-","C48435-","G48436-","A48437-","C48438-","A48439-","C48440-","G48441-","C48442-","A48443-","T48444-","T48445-","T48446-","G48447-","A48448-","T48449-","G48450-","C48451-","A48452-","C48453-","C48454-","C48455-","A48456-","C48457-","G48458-","T48459-","T48460-","G48461-","T48462-","A48463-","C48464-","G48465-","T48466-","T48467-","A48468-","A48469-","A48470-","G48471-","C48472-","A48473-","T48474-","T48475-","G48476-","A48477-","C48478-","T48479-","A48480-","A48481-","G48482-","A48483-","A48484-","T48485-","T48486-","A48487-","T48488-","T48489-","T48490-","A48491-","T48492-","C48493-","G48494-","T48495-","T48496-","T48497-","A48498-","G48499-","T48500-","A48501-","A48502-","C48503-","A48504-","C48505-","A48506-","A48507-","T48508-","A48509-","C48510-","A48511-","G48512-","T48513-","C48514-","G48515-","T48516-","A48517-","C48518-","A48519-","A48520-","G48521-","G48522-","A48523-","A48524-","A48525-","G61794-","G61795-","C61796-","A61797-","T61798-","A61815-","G61816-","T61817-","A61818-","C61819-","A61820-","A61821-","G61822-","T61823-","G61824-","G61825-","C61826-","T61827-","G61828-","C61829-","T61830-","A61831-","T61832-","T61833-","T61834-","C61835-","G61836-","G61837-","C61838-","T61839-","G61840-","C61841-","C61842-","A61843-","G61844-","A61845-","G61846-","T61847-","G61848-","T61849-","C61850-","C61851-","A61852-","A61853-","T61854-","T61855-","C61856-","T61857-","A61858-","C61859-","C61860-","G61861-","T61862-","T61863-","G61864-","T61865-","T61866-","A61867-","C61868-","T61869-","C61870-","C61871-","A61872-","T61873-","T61874-","A61875-","T61876-","A61877-","T61878-","A61879-","T61880-","T61881-","C61882-","C61883-","T61884-","T61885-","G61886-","A61887-","A61888-","T61889-","A61890-","A61891-","C61892-","C61893-","T61894-","T61895-","C61896-","A61897-","T61898-","A61899-","G61900-","C61901-","T61902-","A61903-","T61904-","T61905-","T61906-","T61907-","A61908-","A61909-","T61910-","A61911-","G61912-","G61913-","A61914-","T61915-","C61916-","T61917-","A61918-","T61919-","A61920-","T61921-","G61922-","A61923-","T61924-","C61925-","A61926-","G61927-","T61928-","G61929-","T61930-","T61931-","T61932-","A61933-","A61934-","G61935-","C61936-","C61937-","A61938-","T61939-","A61940-","G61941-","C61942-","A61943-","C61944-","A61945-","A61946-","T61947-","T61948-","T61949-","T61950-","C61951-","T61952-","A61953-","A61954-","T61955-","A61956-","C61957-","G61958-","A61959-","G61960-","A61961-","C61962-","G61963-","T61964-","G61965-","A61966-","T61967-","T61968-","T61969-","T61970-","A61971-","T61972-","C61973-","A61974-","A61975-","A61976-","C61977-","A61978-","T61979-","G61980-","A61981-","C61982-","A61983-","T61984-","T61985-","T61986-","T61987-","C61988-","C61989-","T61990-","T61991-","G61992-","T61993-","A61994-","T61995-","C61996-","C61997-","A61998-","T61999-","T62000-","T62001-","C62002-","G62003-","T62004-","T62005-","T62006-","A62007-","A62008-","T62009-","G62010-","A62011-","C62012-","A62013-","A62014-","A62015-","C62016-","A62017-","T62018-","T62019-","T62020-","T62021-","T62022-","G62023-","T62024-","T62025-","G62026-","G62027-","T62028-","G62029-","T62030-","A62031-","A62032-","T62033-","A62034-","A62035-","A62036-","A62037-","A62038-","A62039-","A62040-","A62041-","T62042-","T62043-","A62044-","T62045-","T62046-","T62047-","A62048-","A62049-","T62050-","T62051-","T62052-","T62053-","T62054-","C62055-","A62056-","T62057-","T62058-","A62059-","A62060-","T62061-","A62062-","G62063-","G62064-","G62065-","A62066-","T62067-","T62068-","T62069-","G62070-","A62071-","C62072-","G62073-","T62074-","A62075-","T62076-","G62077-","T62078-","A62079-","G62080-","C62081-","G62082-","T62083-","A62084-","C62085-","A62086-","A62087-","A62088-","A62089-","T62090-","T62091-","A62092-","T62093-","C62094-","G62095-","T62096-","T62097-","C62098-","C62099-","T62100-","G62101-","G62102-","T62103-","A62104-","T62105-","A62106-","T62107-","A62108-","A62152-","A62153-","C62154-","T62155-","T62156-","T62157-","A62158-","A62159-","T62160-","G62161-","A62162-","T62163-","T62164-","G62165-","T62631-","T62632-","T62633-","A62634-","G62635-","G62636-","A62637-","A62638-","T62639-","G62640-","T62641-","A62642-","T62643-","G62644-","G62645-","A62646-","C62647-","T62648-","C62649-","G62650-","C62651-","G62652-","T62653-","T62654-","T62655-","A62656-","G62657-","A62658-","G62659-","G62660-","A62661-","G62662-","T62663-","G62664-","A62665-","A62666-","C62667-","G62668-","T62669-","C62670-","T62671-","T62672-","C62673-","G62674-","G62675-","A62676-","G62677-","T62678-","A62679-","G62680-","T62681-","A62682-","A62683-","A62684-","G62685-","G62686-","A62687-","T62688-","G62689-","A62690-","T62691-","T62692-","C62693-","G62694-","T62695-","C62696-","A62697-","A62698-","A62699-","T62700-","G62701-","A62702-","A63505-","C70785-","G70786-","T70787-","A70788-","T70789-","A70790-","T70829-","C70830-","G70880-","T70881-","G70882-","C70883-","C70884-","G70885-","T70886-","T70887-","A70888-","C70889-","C70890-","C70891-","T70892-","G70893-","C70894-","C70895-","G70907-","C70908-","A70909-","T70910-","T70911-","A70912-","G70913-","A70914-","A70915-","C70916-","C70917-","A70918-","C70919-","G70920-","T70921-","G70940-","A70941-","A70942-","T70963-","T70970-","T70971-","C70972-","G70973-","A70974-","A70975-","A70976-","A70977-","T70978-","A70979-","C70980-","T70981-","A70982-","A70983-","A70984-","T70985-","C70986-","A70987-","T71023-","G71024-","G71025-","A71026-","T71027-","A71028-","T71029-","T71030-","C71031-","T71032-","A71033-","A71034-","C71035-","G71036-","A71037-","A71038-","A71039-","A71040-","C71041-","T71042-","G71043-","T71044-","A71045-","A71046-","C71047-","A71048-","C71049-","C71050-","A71051-","T71052-","A71053-","G71054-","T71055-","G71056-","T71057-","T71058-","C71059-","G71060-","G71061-","C71062-","A71063-","T71064-","C71065-","T71066-","A71067-","T71068-","A71069-","A71070-","G71071-","G71072-","A71073-","T71074-","A71075-","A71076-","T71077-","T71078-","T71079-","A71080-","C71081-","T71082-","A71083-","C71084-","T71085-","G71086-","A71087-","G71088-","T71089-","A71090-","T71091-","A71092-","A71129-","C71130-","C71131-","A71132-","A71133-","T71134-","A71135-","C71136-","T71137-","A71138-","A71139-","A71140-","A71141-","G71142-","T71143-","G71144-","A71145-","T71146-","A71147-","A71148-","T71149-","A71150-","T71172-","T71173-","A71174-","A71175-","A71176-","A71177-","A71178-","A71179-","T71180-","G71181-","G71182-","T71183-","G71184-","T71185-","T71186-","C71187-","C71188-","A71189-","G71190-","C71191-","T71192-","C71193-","G71194-","T71195-","G71196-","T71197-","G71198-","T71199-","T71200-","C71201-","T71202-","A71203-","C71204-","A71205-","T71206-","G71207-","C71208-","G71209-","G71210-","C71211-","A71212-","A71213-","A71214-","G71215-","A71216-","T71217-","A71218-","T71219-","T71220-","T71221-","C71222-","T71223-","C71224-","A71225-","C71226-","G71227-","A71228-","A71229-","C71230-","G71231-","A71232-","T71233-","A71234-","T71235-","A71236-","A71237-","A71238-","T71239-","T71240-","G71241-","A71242-","T71243-","T71244-","A71245-","T71246-","A71247-","C71248-","G71249-","A71250-","A71251-","A71252-","A71253-","A71254-","A71255-","A71256-","T71257-","C71258-","A71259-","T71260-","T71261-","A71262-","A71263-","A71264-","G71265-","G71266-","A71267-","T71268-","G71269-","T71270-","A71271-","C71272-","T71273-","A71274-","G71275-","T71276-","C71277-","A71278-","G71279-","T71280-","G71281-","T71282-","A71283-","A71284-","A71285-","G71286-","A71287-","A71288-","C71289-","G71290-","A71291-","A71292-","T71293-","G71294-","T71295-","T71296-","G71297-","T71298-","A71299-","G71300-","G71301-","T71302-","T71303-","A71304-","A71305-","A71306-","A71307-","T71308-","T71309-","A71310-","T71311-","C71312-","T71313-","A71314-","C71315-","A71316-","C71317-","A71318-","A71319-","A71320-","T71321-","A71322-","G71323-","A71324-","A71325-","C71326-","C71327-","T71328-","C71329-","A71330-","A71331-","C71332-","G71333-","T71334-","A71335-","A71336-","C71337-","T71338-","T71339-","A71340-","A71341-","C71342-","A71343-","G71344-","T71345-","G71346-","C71347-","A71348-","A71349-","C71350-","C71351-","T71352-","C71353-","T71354-","A71355-","T71356-","T71357-","G71358-","G71359-","A71360-","T71361-","A71362-","T71363-","A71364-","A71365-","A71366-","C71367-","T71368-","A71369-","A71370-","T71371-","G71372-","G71373-","A71374-","T71375-","C71376-","C71377-","G71378-","G71379-","T71380-","T71381-","A71382-","A71383-","T71384-","T71385-","T71386-","T71387-","A71388-","T71389-","C71390-","A71391-","A71392-","G71393-","A71394-","C71395-","A71396-","T71397-","A71398-","T71399-","G71400-","C71401-","G71402-","C71403-","C71404-","T71405-","A71406-","G71407-","A71408-","G71409-","G71410-","T71411-","T71412-","C71413-","T71414-","A71415-","T71416-","T71417-","A71418-","T71419-","T71420-","T71421-","T71422-","T71423-","A71424-","T71425-","T71426-","G71517-","T71518-","A71519-","G71520-","T71521-","T71522-","G71523-","A71524-","A71525-","T71526-","C71527-","T71528-","A71529-","C71530-","C71531-","T71532-","A71533-","T71534-","A71535-","G71536-","A71537-","A71538-","A71539-","A71540-","G71541-","G71542-","A71543-","G71544-","T71545-","T71546-","A71547-","G71548-","A71549-","A71550-","T71551-","A71552-","G71553-","T71554-","C71555-","C71556-","C71557-","A71558-","T71559-","T71560-","G71561-","G71562-","A71563-","T71564-","A71565-","G71566-","A71567-","T71568-","T71569-","T71570-","T71571-","T71572-","T71573-","G71574-","A71575-","A71576-","G71577-","G71578-","A71579-","T71580-","A71581-","T71582-","C71583-","T71584-","T71585-","A71586-","G71587-","T71588-","G71589-","C71590-","A71591-","A71592-","A71593-","A71594-","G71595-","T71596-","A71597-","T71598-","A71599-","C71600-","A71601-","T71602-","G71603-","T71604-","T71605-","A71606-","G71607-","A71608-","G71609-","A71610-","A71611-","T71612-","A71613-","T71614-","T71615-","C71616-","A71617-","A71618-","G71619-","T71620-","T71621-","A71622-","T71623-","G71624-","A71625-","A71626-","A71627-","A71628-","T71629-","A71630-","G71631-","C71632-","A71633-","G71634-","C71635-","T71636-","G71637-","A71638-","T71639-","A71640-","T71641-","G71642-","T71643-","C71644-","G71645-","T71646-","T71647-","A71648-","A71649-","C71650-","T71651-","T71652-","G71676-","G71677-","T71678-","C71679-","G71709-","C71710-","T71711-","G71712-","A71713-","A71714-","T71715-","G71716-","T71717-","T71718-","A71719-","T71720-","A71721-","A71722-","A71723-","A71724-","A71725-","T71726-","G71727-","C71728-","C71729-","G71730-","G71731-","T71732-","A71733-","T71734-","T71735-","G71736-","A71737-","T71738-","A71739-","C71740-","A71741-","T71742-","C71743-","G71744-","T71745-","C71746-","T71747-","A71748-","A71749-","A71750-","C71751-","G71752-","A71753-","A71754-","T71755-","A71756-","T71757-","T71758-","A71759-","G71760-","G71761-","T71762-","A71763-","A71764-","A71765-","G71766-","A71767-","T71768-","A71769-","T71770-","T71771-","T71772-","T71773-","T71774-","C71775-","T71776-","G71777-","A71778-","G71779-","C71780-","C71781-","A71782-","A71783-","A71784-","A71785-","C71786-","T71787-","T71788-","T71789-","A71790-","C71791-","A71792-","G71793-","A71794-","T71795-","G71796-","A71797-","T71798-","A71799-","A71800-","T71801-","A71802-","G71803-","A71804-","T71805-","G71806-","G71807-","A71808-","T71809-","A71810-","A71811-","A71812-","G71813-","C71856-","C71910-","T71911-","T71912-","T71913-","T71914-","T71915-","C71916-","T71917-","T71918-","A71919-","A71920-","C71921-","G71922-","T71923-","T71924-","G71925-","T71926-","T71927-","T71928-","G71929-","C71930-","C71931-","A71932-","T71933-","C71934-","A71935-","C71936-","T71937-","C71938-","T71939-","C71940-","A71941-","T71942-","A71943-","A71944-","T71945-","G71946-","T71947-","A71948-","A71949-","A71950-","G71951-","A71952-","T71953-","A71954-","T71955-","T71956-","C71957-","T71958-","A71959-","A71960-","A71961-","A71962-","T71963-","G71964-","G71965-","T71966-","A71967-","A71968-","A71969-","C71970-","T71971-","T71972-","T71973-","T71974-","G71975-","C71976-","A71977-","T71978-","A71979-","T71980-","C71981-","G71982-","G71983-","A71984-","T71985-","G71986-","C71987-","A71988-","G71989-","A71990-","A71991-","A71992-","T71993-","T71994-","G71995-","G71996-","T71997-","A71998-","T71999-","A72000-","A72001-","A72002-","T72003-","G72004-","T72005-","T72006-","G72007-","T72008-","A72009-","A72010-","T72011-","T72012-","G72013-","T72014-","A72015-","T72016-","T72017-","A72018-","T72019-","T72020-","T72021-","C72022-","C72023-","C72024-","G72025-","T72026-","C72027-","A72028-","A72029-","T72030-","G72031-","G72032-","A72033-","C72034-","T72035-","A72036-","G72037-","T72038-","C72039-","A72040-","C72041-","A72042-","G72043-","C72044-","T72045-","C72046-","C72047-","A72048-","T72049-","C72050-","A72051-","G72052-","T72053-","T72054-","T72055-","T72056-","A72057-","T72058-","A72059-","T72060-","C72061-","C72062-","T72063-","T72064-","T72065-","A72066-","G72067-","A72068-","G72069-","T72070-","A72071-","T72072-","T72073-","T72074-","C72075-","T72076-","C72077-","A72078-","C72079-","T72080-","C72081-","G72082-","T72083-","G72084-","T72085-","C72086-","T72087-","A72088-","G72089-","C72090-","A72091-","T72092-","T72093-","C72094-","T72095-","A72096-","G72097-","A72098-","G72099-","C72100-","A72101-","T72102-","T72103-","C72104-","C72105-","A72106-","T72107-","G72108-","A72109-","T72110-","C72111-","T72112-","G72113-","T72114-","T72115-","T72116-","A72117-","T72118-","C72119-","G72120-","T72121-","T72122-","G72123-","A72124-","T72125-","A72126-","T72127-","T72128-","G72129-","G72130-","C72131-","C72132-","G72133-","G72134-","A72135-","A72136-","A72137-","G72138-","A72139-","T72140-","A72141-","G72142-","A72143-","T72144-","T72145-","T72146-","T72147-","T72148-","T72149-","A72150-","T72151-","T72152-","T72153-","T72154-","T72155-","T72156-","A72157-","T72158-","T72159-","A72160-","T72161-","A72162-","T72163-","T72164-","A72165-","C72166-","T72167-","A72168-","T72169-","T72170-","G72171-","G72172-","C72173-","A72174-","A72175-","T72176-","T72177-","G72178-","T72179-","A72180-","G72181-","A72182-","T72183-","A72184-","T72185-","A72186-","A72187-","C72188-","T72189-","T72190-","C72191-","T72192-","G72193-","G72194-","T72195-","A72196-","A72197-","A72198-","T72199-","A72200-","T72201-","T72202-","T72203-","T72204-","T72205-","C72206-","T72207-","A72208-","C72209-","C72210-","T72211-","T72212-","T72213-","T72214-","C72215-","A72216-","A72217-","T72218-","C72219-","T72220-","C72221-","T72222-","T72223-","C72224-","T72225-","A72226-","T72227-","T72228-","T72229-","T72230-","C72231-","A72232-","A72233-","G72234-","C72235-","C72236-","G72237-","G72238-","C72239-","T72240-","A72241-","T72242-","A72243-","T72244-","A72245-","T72246-","T72247-","C72248-","T72249-","G72250-","C72251-","T72252-","A72253-","T72254-","A72255-","T72256-","T72257-","G72258-","T72259-","T72260-","A72261-","C72262-","T72263-","A72264-","G72265-","T72266-","A72267-","T72268-","C72269-","A72270-","A72271-","T72272-","A72273-","C72274-","C72275-","T72276-","T72277-","T72278-","T72279-","C72280-","T72281-","G72282-","G72283-","C72284-","T72285-","A72286-","A72287-","G72288-","A72289-","A72290-","G72291-","T72292-","C72293-","A72294-","T72295-","A72296-","T72297-","G72298-","T72299-","G72300-","G72301-","T72302-","A72303-","T72304-","T72305-","C72306-","A72307-","C72308-","T72309-","A72310-","T72311-","A72312-","T72313-","C72314-","A72315-","G72316-","T72317-","T72318-","T72319-","T72320-","A72321-","A72322-","C72323-","T72324-","G72325-","G72326-","T72327-","A72328-","G72329-","T72330-","T72331-","C72332-","C72333-","A72334-","T72335-","T72336-","A72337-","G72338-","C72339-","C72340-","T72341-","T72342-","T72343-","C72344-","C72345-","A72346-","C72347-","T72348-","T72349-","C72350-","T72351-","G72352-","C72353-","A72354-","G72355-","A72356-","A72357-","T72358-","A72359-","A72360-","T72361-","T72362-","A72363-","G72364-","A72365-","A72366-","A72367-","T72368-","T72369-","G72370-","G72371-","T72372-","T72373-","C72374-","T72375-","T72376-","T72377-","A72378-","C72379-","C72380-","A72381-","G72382-","A72383-","A72384-","A72385-","A72386-","T72387-","C72388-","C72389-","A72390-","G72391-","C72392-","T72393-","A72394-","A89103-","A89104-","A89105-","G89148-","T89149-","C89150-","A89151-","T89166-","C89229-","A89230-","G89231-","T89232-","G89233-","T89234-","T89235-","A89373-","C89374-","T89375-","T89376-","A89377-","T89378-","A89379-","T89380-","T89381-","C89382-","G89383-","T89384-","G89385-","T89386-","C89387-","T89388-","A89389-","G89390-","T89391-","A89392-","G89393-","A89394-","T89700-","C151552T","C167451T","-194549A","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","C194595-","G194596-","T194597-","G194598-","T194599-"],"OPG002":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-"],"OPG002_dup":["C44-","L45-","S46-","C47-"],"OPG057":["N267D"],"OPG080":["A75-"],"OPG089":["S307F","I309-","P310-","S322-","V339-","P340-","L341-","P342-","C343-","Q344-","L349-","E350-","P351-","R352-","K353-","E359-"],"OPG091":["L163-"],"OPG092":["A186-","G187-","F188-","S189-","G190-","K191-","E192-","P193-","I194-","S195-","N196-","Y197-","S198-","A199-","E200-","V201-","E202-","R203-","L204-","M205-","E206-","L207-","P208-","V209-","K210-","T211-","D212-","I213-","V214-","N215-","T216-","T217-","Y218-","D219-","F220-","L221-","A222-","R223-","K224-","G225-","I226-","D227-","T228-","S229-","N230-","N231-","I232-","A233-","E234-","Y235-","I236-","A237-","G238-","L239-","K240-","I241-","E242-","E243-","I244-","E245-","K246-","V247-","E248-","K249-","Y250-","L251-","P252-","E253-","V254-","I255-","S256-","T257-","I258-","A259-","N260-","S261-","N262-","I263-","I264-","K265-","N266-","K267-","K268-","S269-","I270-","F271-","P272-","A273-","N274-","I275-","N276-","D277-","K278-","Q279-","I280-","M281-","E282-","C283-","S284-","R285-","M286-","L287-","D288-","T289-","S290-","E291-","K292-","Y293-","S294-","K295-","G296-","Y297-","K298-","T299-","D300-","G301-","A302-","V303-","T304-","S305-","P306-","L307-","T308-","G309-","N310-","N311-","T312-","I313-","T314-","T315-","F316-","I317-","P318-","I319-","S320-","A321-","S322-","D323-","M324-","Q325-","K326-","F327-","T328-","I329-","L330-","E331-","Y332-","L333-","Y334-","I335-","M336-","R337-","V338-","M339-","A340-","N341-","N342-","V343-","K344-","K345-","K346-","V365-"],"OPG109":["L19-","L20-","D21-","T22-","N23-","I24-","S25-","D100-"],"OPG178":["S15F"]},"labels":{"aa":"OPG002: K31-, C32-, K33-, D34-, N35-, E36-, Y37-; OPG002_dup: C44-, L45-, S46-, C47-; OPG057: N267D; OPG080: A75-; OPG089: S307F, I309-, P310-, S322-, V339-, P340-, L341-, P342-, C343-, Q344-, L349-, E350-, P351-, R352-, K353-, E359-; OPG091: L163-; OPG092: A186-, G187-, F188-, S189-, G190-, K191-, E192-, P193-, I194-, S195-, N196-, Y197-, S198-, A199-, E200-, V201-, E202-, R203-, L204-, M205-, E206-, L207-, P208-, V209-, K210-, T211-, D212-, I213-, V214-, N215-, T216-, T217-, Y218-, D219-, F220-, L221-, A222-, R223-, K224-, G225-, I226-, D227-, T228-, S229-, N230-, N231-, I232-, A233-, E234-, Y235-, I236-, A237-, G238-, L239-, K240-, I241-, E242-, E243-, I244-, E245-, K246-, V247-, E248-, K249-, Y250-, L251-, P252-, E253-, V254-, I255-, S256-, T257-, I258-, A259-, N260-, S261-, N262-, I263-, I264-, K265-, N266-, K267-, K268-, S269-, I270-, F271-, P272-, A273-, N274-, I275-, N276-, D277-, K278-, Q279-, I280-, M281-, E282-, C283-, S284-, R285-, M286-, L287-, D288-, T289-, S290-, E291-, K292-, Y293-, S294-, K295-, G296-, Y297-, K298-, T299-, D300-, G301-, A302-, V303-, T304-, S305-, P306-, L307-, T308-, G309-, N310-, N311-, T312-, I313-, T314-, T315-, F316-, I317-, P318-, I319-, S320-, A321-, S322-, D323-, M324-, Q325-, K326-, F327-, T328-, I329-, L330-, E331-, Y332-, L333-, Y334-, I335-, M336-, R337-, V338-, M339-, A340-, N341-, N342-, V343-, K344-, K345-, K346-, V365-; OPG109: L19-, L20-, D21-, T22-, N23-, I24-, S25-, D100-; OPG178: S15F"}}}]}]},{"name":"NODE_0000046","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C18441T","G22415A","G70002A","C132698T","G143951A","C148604T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G154188A","T179078-","A179079-","T179080-","A179081-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C196745-","C196746-","A196747-"],"OPG031":["E130K"],"OPG089":["R46K"],"OPG165":["D146N"],"OPG174":["M264I"]},"labels":{"aa":"OPG031: E130K; OPG089: R46K; OPG165: D146N; OPG174: M264I"}},"children":[{"name":"OR499993","node_attrs":{"div":68,"accession":"OR499993","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00537/2023"},"date":{"value":"2023-07-06"},"strain_display":{"value":"USA/OR499993/2023-07-06"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179082-","C179091-","C179100-","C179109-","C179118-","C179127-","C179136-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000047","node_attrs":{"div":69,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C14823A","-179078T","-179079A","-179080T","-179081A","-179083A","-179084T","-179085T","-179086A","-179087T","-179088A","-179089T","-179090A","-179092A","-179093T","-179094T","-179095A","-179096T","-179097A","-179098T","-179099A","-179101A","-179102T","-179103T","-179104A","-179105T","-179106A","-179107T","-179108A","-179110A","-179111T","-179112T","-179113A","-179114T","-179115A","-179116T","-179117A","-179119A","-179120T","-179121T","-179122A","-179123T","-179124A","-179125T","-179126A","-179128A","-179129T","-179130T","-179131A","-179132T","-179133A","-179134T","-179135A","-179137A","-179138T","-179139T","-179140A","-179141T","-179142A","-179143T","-179144A"],"OPG025":["D149Y"]},"labels":{"aa":"OPG025: D149Y"}},"children":[{"name":"OR643702","node_attrs":{"div":69,"accession":"OR643702","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00560/2023"},"date":{"value":"2023-08-08"},"strain_display":{"value":"USA/OR643702/2023-08-08"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OR499982","node_attrs":{"div":69,"accession":"OR499982","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00525/2023"},"date":{"value":"2023-06-14"},"strain_display":{"value":"USA/OR499982/2023-06-14"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000048","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["T606-","C118453T","G137276A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177009A","T178873C","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","A196614-"],"OPG136":["E379K"],"OPG153":["S131F"],"OPG205":["E452K"]},"labels":{"aa":"OPG136: E379K; OPG153: S131F; OPG205: E452K"}},"children":[{"name":"OR499971","node_attrs":{"div":67,"accession":"OR499971","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00514/2023"},"date":{"value":"2023-05-04"},"strain_display":{"value":"USA/OR499971/2023-05-04"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T39397C","C117119T"],"OPG057":["N267D"]},"labels":{"aa":"OPG057: N267D"}}},{"name":"NODE_0000049","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["G635-","A636-","A637-","A1697-","G39327A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","T195519-"],"OPG057":["A290V"]},"labels":{"aa":"OPG057: A290V"}},"children":[{"name":"OR499948","node_attrs":{"div":66,"accession":"OR499948","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00491/2023"},"date":{"value":"2023-04-10"},"strain_display":{"value":"USA/OR499948/2023-04-10"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OR499967","node_attrs":{"div":66,"accession":"OR499967","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00510/2023"},"date":{"value":"2023-05-04"},"strain_display":{"value":"USA/OR499967/2023-05-04"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A672-","C673-","A674-","T196633-","C196634-","T196635-"]}}}]}]},{"name":"NODE_0000052","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.16"}},"branch_attrs":{"mutations":{"nuc":["C9389T","C30154T","G161797A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A185557C","T196852-","T196854-"],"OPG188":["E68K"],"OPG210":["K1401T"]},"labels":{"aa":"OPG188: E68K; OPG210: K1401T","clade":"B.1.16"}},"children":[{"name":"OP642383","node_attrs":{"div":67,"accession":"OP642383","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.16"},"strain":{"value":"ANT-LDSP-ANT-MPX-24909-C"},"date":{"value":"2022-09-09"},"strain_display":{"value":"Colombia/OP642383/2022-09-09"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G6863A","C132608T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP693653","node_attrs":{"div":66,"accession":"OP693653","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.16"},"strain":{"value":"DC_INS_MPX_0719_L"},"date":{"value":"2022-08-29"},"strain_display":{"value":"Colombia/OP693653/2022-08-29"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G121275A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG139":["P32S"]},"labels":{"aa":"OPG139: P32S"}}},{"name":"OP693647","node_attrs":{"div":65,"accession":"OP693647","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.16"},"strain":{"value":"DC_INS_MPX_0082_L"},"date":{"value":"2022-08-08"},"strain_display":{"value":"Colombia/OP693647/2022-08-08"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A1701-","C1702-","T1703-","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-","G196853-"]}}},{"name":"OQ197862","node_attrs":{"div":66,"accession":"OQ197862","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Rosales,A.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Rosales,A.,Mercado-Reyes,M.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.16"},"strain":{"value":"DC_INS_MPX-1119-H"},"date":{"value":"2022-10-24"},"strain_display":{"value":"Colombia/OQ197862/2022-10-24"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","G23118A","T197076-","T197077-","C197078-"]}}},{"name":"OQ696097","node_attrs":{"div":67,"accession":"OQ696097","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.16"},"strain":{"value":"ANT-LDSP-ANT-MPX-30512O"},"date":{"value":"2022-11-10"},"strain_display":{"value":"Colombia/OQ696097/2022-11-10"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G23673A","G37974A","-196852T","-196854T"],"OPG039":["S149L"],"OPG056":["S354L"]},"labels":{"aa":"OPG039: S149L; OPG056: S354L"}}}]},{"name":"NODE_0000060","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{"nuc":["T606-","G181367A","A196614-"]},"labels":{"clade":"B.1.9"}},"children":[{"name":"ON843175","node_attrs":{"div":62,"accession":"ON843175","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0043/2022"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Portugal/ON843175/2022-05-30"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP693652","node_attrs":{"div":63,"accession":"OP693652","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.9"},"strain":{"value":"DC_INS_MPX_0718_L"},"date":{"value":"2022-08-16"},"strain_display":{"value":"Colombia/OP693652/2022-08-16"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-606T","G134122T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP687938","node_attrs":{"div":65,"accession":"OP687938","author":{"author":"Gigante,C.M.,Acheampong,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Morrison,S.S.,Seabolt,M.H.,Weigand,M.R.,Knipe,K.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,McDermott,D.,Li,Y.","value":"Gigante,C.M.,Acheampong,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Morrison,S.S.,Seabolt,M.H.,Weigand,M.R.,Knipe,K.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,McDermott,D.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.9"},"strain":{"value":"MPXV_USA_2022_NJ0005"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP687938/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G61329A","C101868T","C103427T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG121":["P27S"]},"labels":{"aa":"OPG121: P27S"}}},{"name":"NODE_0000061","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{"nuc":["G176823A"],"OPG205":["E390K"]},"labels":{"aa":"OPG205: E390K"}},"children":[{"name":"ON880538","node_attrs":{"div":64,"accession":"ON880538","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.9"},"strain":{"value":"MpxV/human/CAN/UN-NML-3336/2022"},"date":{"value":"2022-06-01"},"strain_display":{"value":"Canada/ON880538/2022-06-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C32627T"]}}},{"name":"NODE_0000062","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{"nuc":["-606T","A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","C57110T","-196614A"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG074":["E6K"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG074: E6K"}},"children":[{"name":"ON649713","node_attrs":{"div":64,"accession":"ON649713","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0020/2022"},"date":{"value":"2022-05-19"},"strain_display":{"value":"Portugal/ON649713/2022-05-19"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP555485","node_attrs":{"div":65,"accession":"OP555485","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0389/2022"},"date":{"value":"2022-07-12"},"strain_display":{"value":"Portugal/OP555485/2022-07-12"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159148A"],"OPG185":["D78N"]},"labels":{"aa":"OPG185: D78N"}}}]},{"name":"NODE_0000063","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.9"}},"branch_attrs":{"mutations":{"nuc":["C34432T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155157A"],"OPG053":["E87K"],"OPG181":["R249K"]},"labels":{"aa":"OPG053: E87K; OPG181: R249K"}},"children":[{"name":"OP324505","node_attrs":{"div":66,"accession":"OP324505","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0191/2022"},"date":{"value":"2022-06-28"},"strain_display":{"value":"Portugal/OP324505/2022-06-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-606T","-607T","G4195A","C193015T"],"OPG003":["S138L"],"OPG003_dup":["S138L"]},"labels":{"aa":"OPG003: S138L; OPG003_dup: S138L"}}},{"name":"OP555563","node_attrs":{"div":65,"accession":"OP555563","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.9"},"strain":{"value":"Monkeypox/PT0487/2022"},"date":{"value":"2022-08-11"},"strain_display":{"value":"Portugal/OP555563/2022-08-11"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000064","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.17"}},"branch_attrs":{"mutations":{"nuc":["G12169A","G44960A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]},"labels":{"clade":"B.1.17"}},"children":[{"name":"OP442552","node_attrs":{"div":63,"accession":"OP442552","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.17"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00085/2022"},"date":{"value":"2022-07-13"},"strain_display":{"value":"USA/OP442552/2022-07-13"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G771-","T772-","G773-","A196789-","A196790-","T196791-"]}}},{"name":"OP392544","node_attrs":{"div":66,"accession":"OP392544","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.17"},"strain":{"value":"MpxV/human/USA/WA-UW-083781/2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP392544/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A11836G","C113363T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G171959A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG132":["D60N"]},"labels":{"aa":"OPG132: D60N"}}},{"name":"OP748959","node_attrs":{"div":64,"accession":"OP748959","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.17"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00273/2022"},"date":{"value":"2022-07-14"},"strain_display":{"value":"USA/OP748959/2022-07-14"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T658-","A659-","T660-","A11160G"],"OPG023":["F581L"]},"labels":{"aa":"OPG023: F581L"}}},{"name":"OQ054244","node_attrs":{"div":63,"accession":"OQ054244","author":{"author":"Gigante,C.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y.","value":"Gigante,C.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.17"},"strain":{"value":"MPXV_USA_2022_CA0029"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ054244/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A173316-","T173317-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP890565","node_attrs":{"div":64,"accession":"OP890565","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.17"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00308/2022"},"date":{"value":"2022-11-09"},"strain_display":{"value":"USA/OP890565/2022-11-09"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A763-","A764-","T765-","C39334G","T196627-","C196628-","T196629-"],"OPG057":["A288P"]},"labels":{"aa":"OPG057: A288P"}}},{"name":"OQ888843","node_attrs":{"div":66,"accession":"OQ888843","author":{"author":"Hemarajata,P.,Garrigues,J.M.,Green,N.M.","value":"Hemarajata,P.,Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.17"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00483/2022"},"date":{"value":"2022-10-13"},"strain_display":{"value":"USA/OQ888843/2022-10-13"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T39397C","G86148A","C177626T"],"OPG057":["N267D"]},"labels":{"aa":"OPG057: N267D"}}},{"name":"NODE_0000065","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.17"}},"branch_attrs":{"mutations":{"nuc":["A39395-","T39396-","T39397-","C85931T"],"OPG057":["N267-"]},"labels":{"aa":"OPG057: N267-"}},"children":[{"name":"OQ330999","node_attrs":{"div":65,"accession":"OQ330999","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.17"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00391/2022"},"date":{"value":"2022-12-19"},"strain_display":{"value":"USA/OQ330999/2022-12-19"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C174129T"]}}},{"name":"OQ503830","node_attrs":{"div":68,"accession":"OQ503830","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.17"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00407/2023"},"date":{"value":"2023-01-10"},"strain_display":{"value":"USA/OQ503830/2023-01-10"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C49265T","G71249A","G79741A","G182189A"],"OPG090":["R24Q"],"OPG102":["M219I"]},"labels":{"aa":"OPG090: R24Q; OPG102: M219I"}}}]}]},{"name":"NODE_0000066","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["C141757T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A"]}},"children":[{"name":"OR126131","node_attrs":{"div":66,"accession":"OR126131","author":{"author":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C.","value":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Spain"},"clade_membership":{"value":"IIb"},"institution":{"value":"Hospital Ramon y Cajal, Microbiology"},"lineage":{"value":"B.1"},"strain":{"value":"HRYC_MPXV001"},"date":{"value":"2022-09-21"},"strain_display":{"value":"Spain/OR126131/2022-09-21"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C11749-","C34432T","C48324T","G101294A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G190695A"],"OPG016":["E96K"],"OPG053":["E87K"],"OPG120":["S152L"]},"labels":{"aa":"OPG016: E96K; OPG053: E87K; OPG120: S152L"}}},{"name":"NODE_0000067","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.18"}},"branch_attrs":{"mutations":{"nuc":["C43706T","T124690C"]},"labels":{"clade":"B.1.18"}},"children":[{"name":"OP628451","node_attrs":{"div":64,"accession":"OP628451","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.18"},"strain":{"value":"MpxV/human/USA/WA-UW-083401/2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP628451/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP615266","node_attrs":{"div":69,"accession":"OP615266","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.18"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00193/2022"},"date":{"value":"2022-07-19"},"strain_display":{"value":"USA/OP615266/2022-07-19"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G24063A","G54088A","G59082A","A140155T","C145187T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C190067T","G191268A"],"OPG015_dup":["R72K"],"OPG039":["S19F"],"OPG167":["R74K"]},"labels":{"aa":"OPG015_dup: R72K; OPG039: S19F; OPG167: R74K"}}},{"name":"OQ330978","node_attrs":{"div":65,"accession":"OQ330978","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.18"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00375/2022"},"date":{"value":"2022-10-06"},"strain_display":{"value":"USA/OQ330978/2022-10-06"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A185923C","A196614-"],"OPG210":["K1523T"]},"labels":{"aa":"OPG210: K1523T"}}},{"name":"OQ721920","node_attrs":{"div":66,"accession":"OQ721920","author":{"author":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.18"},"strain":{"value":"MPXV_USA_2022_IL0009"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721920/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","G78759A","C126911T","A196614-"],"OPG101":["E92K"],"OPG148":["S309F"]},"labels":{"aa":"OPG101: E92K; OPG148: S309F"}}},{"name":"NODE_0000068","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.18"}},"branch_attrs":{"mutations":{"nuc":["C170049T"]}},"children":[{"name":"OR464199","node_attrs":{"div":70,"accession":"OR464199","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.18"},"strain":{"value":"MPXV_USA_2022_NY0051"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OR464199/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C45127T","G91787A","G91880A","G105147A","C114521T"],"OPG064":["E258K"],"OPG133":["M392I"]},"labels":{"aa":"OPG064: E258K; OPG133: M392I"}}},{"name":"NODE_0000069","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.18"}},"branch_attrs":{"mutations":{"nuc":["G67758A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP837471","node_attrs":{"div":66,"accession":"OP837471","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.18"},"strain":{"value":"VAC_INS_MPX_1052_E"},"date":{"value":"2022-10-25"},"strain_display":{"value":"Colombia/OP837471/2022-10-25"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OQ148474","node_attrs":{"div":70,"accession":"OQ148474","author":{"author":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"lineage":{"value":"B.1.18"},"strain":{"value":"LBMB-UTP_MP-025_VAC"},"date":{"value":"2022-11-15"},"strain_display":{"value":"Colombia/OQ148474/2022-11-15"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C128242T","G144572A","C166940T","C168829T"],"OPG150":["S155F"],"OPG166":["A59T"]},"labels":{"aa":"OPG150: S155F; OPG166: A59T"}}}]}]}]}]},{"name":"NODE_0000070","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.15"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","G149818A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G151362A"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG176":["D4N"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG176: D4N","clade":"B.1.15"}},"children":[{"name":"ON694335","node_attrs":{"div":63,"accession":"ON694335","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/Germany/2022/RKI018"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/ON694335/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-","A196614-"]}}},{"name":"OP324453","node_attrs":{"div":64,"accession":"OP324453","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.15"},"strain":{"value":"Monkeypox/PT0129/2022"},"date":{"value":"2022-07-12"},"strain_display":{"value":"Portugal/OP324453/2022-07-12"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","C18133T","-196615A","-196616T"]}}},{"name":"OP484673","node_attrs":{"div":66,"accession":"OP484673","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/Germany/2022/RKI352"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP484673/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C21128T","G74187T","C151111T"],"OPG037":["E436K"],"OPG094":["Q136H"]},"labels":{"aa":"OPG037: E436K; OPG094: Q136H"}}},{"name":"OP764619","node_attrs":{"div":63,"accession":"OP764619","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/Germany/2022/RKI561"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OP764619/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000071","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.15"}},"branch_attrs":{"mutations":{"nuc":["C8385T","-11326A","-11327T","-11328C","-11329T","-11330A","-11331C","-11332G","-11333A","-11334T","-11335A","-11336T","-11337T","-11338A","-11339G","-11340A","-11341T","-11342A","-11343C","-11344T","-11345T","-11346C","-11347A","-11348C","-11349T","-11350C","-11351A","-11352A","-11353T","-11354G","-11355A","-11356A","-11357T","-11358C","-11359A","-11360A","-11361T","-11362C","-11363A","-11364C","-11365A","-11366C","-11367A","-11368A","-11369T","-11370C","-11371T","-11372A","-11373A","-11374T","-11375G","-11376T","-11377A","-11378G","-11379G","-11380T","-11381T","-11382T","-11383A","-11384T","-11385G","-11386A","-11387C","-11388A","-11389T","-11390A","-11391A","-11392T","-11393A","-11394G","-11395C","-11396A","-11397T","-11398T","-11399T","-11400T","-11401C","-11402A","-11403G","-11404C","-11405A","-11406G","-11407T","-11408T","-11409C","-11410A","-11411A","-11412T","-11413G","-11414T","-11415T","-11416T","-11417C","-11418T","-11419A","-11420G","-11421A","-11422T","-11423T","-11424C","-11425G","-11426T","-11427T","-11428G","-11429A","-11430T","-11431G","-11432G","-11433C","-11434A","-11435A","-11436T","-11437G","-11438G","-11439T","-11440T","-11441A","-11442T","-11443A","-11444C","-11445A","-11446T","-11447G","-11448T","-11449A","-11450T","-11451A","-11452T","-11453C","-11454C","-11455G","-11456T","-11457T","-11458A","-11459T","-11460T","-11461T","-11462G","-11463A","-11464T","-11465C","-11466T","-11467A","-11468A","-11469T","-11470G","-11471T","-11472T","-11473G","-11474A","-11475C","-11476A","-11477T","-11478C","-11479T","-11480G","-11481A","-11482A","-11483C","-11484C","-11485G","-11486G","-11487A","-11488T","-11489T","-11490C","-11491T","-11492A","-11493G","-11494C","-11495A","-11496G","-11497T","-11498A","-11499A","-11500A","-11501G","-11502A","-11503T","-11504A","-11505C","-11506T","-11507A","-11508G","-11509A","-11510G","-11511A","-11512T","-11513T","-11514G","-11515T","-11516T","-11517T","-11518A","-11519T","-11520T","-11521A","-11522T","-11523A","-11524T","-11525C","-11526T","-11527A","-11528A","-11529C","-11530A","-11531G","-11532C","-11533C","-11534T","-11535T","-11536G","-11537T","-11538G","-11539A","-11540A","-11541G","-11542A","-11543A","-11544G","-11545T","-11546G","-11547T","-11548T","-11549T","-11550C","-11551T","-11552C","-11553C","-11554T","-11555C","-11556G","-11557T","-11558T","-11559T","-11560G","-11561T","-11562C","-11563A","-11564A","-11565T","-11566C","-11567A","-11568T","-11569G","-11570T","-11571T","-11572A","-11573A","-11574T","-11575G","-11576T","-11577C","-11578T","-11579T","-11580T","-11581A","-11582A","-11583G","-11584A","-11585T","-11586A","-11587A","-11588G","-11589G","-11590T","-11591A","-11592G","-11593A","-11594C","-11595A","-11596A","-11597A","-11598T","-11599G","-11600T","-11601T","-11602T","-11603A","-11604T","-11605A","-11606G","-11607T","-11608A","-11609C","-11610T","-11611A","-11612A","-11613G","-11614A","-11615A","-11616T","-11617T","-11618G","-11619G","-11620G","-11621C","-11622A","-11623A","-11624A","-11625C","-11626A","-11627T","-11628A","-11629A","-11630G","-11631A","-11632C","-11633A","-11634T","-11635G","-11636T","-11637C","-11638A","-11639C","-11640A","-11641A","-11642A","-11643G","-11644A","-11645C","-11646C","-11647C","-11648T","-11649T","-11650T","-11651T","-11652T","-11653G","-11654T","-11655A","-11656T","-11657G","-11658T","-11659A","-11660T","-11661A","-11662A","-11663G","-11664T","-11665G","-11666T","-11667A","-11668G","-11669A","-11670A","-11671A","-11672T","-11673T","-11674A","-11675T","-11676A","-11677A","-11678C","-11679A","-11680T","-11681C","-11682C","-11683A","-11684T","-11685A","-11686G","-11687T","-11688T","-11689G","-11690G","-11691A","-11692T","-11693T","-11694C","-11695A","-11696C","-11697A","-11698T","-11699A","-11700G","-11701G","-11702T","-11703G","-11704T","-11705C","-11706C","-11707A","-11708A","-11709T","-11710C","-11711G","-11712G","-11713G","-11714A","-11715T","-11716C","-11717T","-11718C","-11719T","-11720C","-11721C","-11722A","-11723T","-11724C","-11725A","-11726T","-11727C","-11728G","-11729A","-11730G","-11731A","-11732T","-11733G","-11734A","-11735T","-11736T","-11737G","-11738A","-11739C","-11740G","-11741G","-11742C","-11743A","-11744T","-11745C","-11746T","-11747C","-11748C","-11749C","-11750C","-11751C","-11752T","-11753T","-11754C","-11755C","-11756T","-11757T","-11758T","-11759T","-11760T","-11761T","-11762A","-11763G","-11764T","-11765A","-11766G","-11767A","-11768T","-11769A","-11770T","-11771T","-11772T","-11773C","-11774A","-11775T","-11776C","-11777G","-11778T","-11779G","-11780T","-11781A","-11782A","-11783G","-11784A","-11785A","-11786T","-11787C","-11788A","-11789A","-11790T","-11791A","-11792T","-11793T","-11794A","-11795A","-11796T","-11797A","-11798T","-11799T","-11800T","-11801C","-11802T","-11803A","-11804A","-11805A","-11806G","-11807T","-11808A","-11809T","-11810C","-11811T","-11812G","-11813T","-11814G","-11815T","-11816A","-11817T","-11818A","-11819G","-11820C","-11821C","-11822T","-11823C","-11824T","-11825T","-11826T","-11827A","-11828T","-11829T","-11830T","-11831A","-11832C","-11833C","-11834A","-11835C","-11836A","-11837G","-11838C","-11839T","-11840C","-11841C","-11842A","-11843T","-11844A","-11845T","-11846T","-11847C","-11848C","-11849A","-11850A","-11851C","-11852A","-11853T","-11854G","-11855C","-11856A","-11857T","-11858T","-11859C","-11860C","-11861A","-11862C","-11863T","-11864A","-11865G","-11866A","-11867G","-11868G","-11869G","-11870A","-11871T","-11872A","-11873T","-11874C","-11875G","-11876A","-11877T","-11878A","-11879T","-11880C","-11881G","-11882C","-11883C","-11884G","-11885A","-11886A","-11887T","-11888G","-11889T","-11890C","-11891A","-11892T","-11893A","-11894T","-11895A","-11896C","-11897T","-11898C","-11899A","-11900A","-11901T","-11902T","-11903A","-11904G","-11905T","-11906A","-11907T","-11908A","-11909T","-11910G","-11911T","-11912T","-11913G","-11914G","-11915A","-11916G","-11917G","-11918A","-11919C","-11920A","-11921T","-11922C","-11923C","-11924G","-11925A","-11926G","-11927T","-11928T","-11929C","-11930A","-11931T","-11932T","-11933G","-11934T","-11935T","-11936T","-11937T","-11938C","-11939A","-11940A","-11941T","-11942A","-11943T","-11944C","-11945A","-11946A","-11947A","-11948G","-11949A","-11950G","-11951A","-11952T","-11953G","-11954G","-11955T","-11956T","-11957T","-11958C","-11959C","-11960T","-11961T","-11962A","-11963T","-11964C","-11965A","-11966T","-11967T","-11968T","-11969C","-11970T","-11971C","-11972C","-11973A","-11974T","-11975A","-11976G","-11977T","-11978G","-11979G","-11980T","-11981A","-11982C","-11983A","-11984A","-11985T","-11986A","-11987C","-11988T","-11989A","-11990C","-11991A","-11992C","-11993A","-11994T","-11995T","-11996A","-11997T","-11998T","-11999C","-12000C","-12001G","-12002T","-12003A","-12004C","-12005G","-12006G","-12007C","-12008T","-12009T","-12010T","-12011C","-12012C","-12013A","-12014T","-12015T","-12016C","-12017T","-12018C","-12019C","-12020A","-12021A","-12022A","-12023A","-12024A","-12025C","-12026A","-12027A","-12028T","-12029T","-12030T","-12031T","-12032A","-12033C","-12034C","-12035A","-12036A","-12037A","-12038T","-12039C","-12040T","-12041A","-12042A","-12043A","-12044T","-12045C","-12046T","-12047A","-12048C","-12049A","-12050T","-12051C","-12052T","-12053T","-12054T","-12055A","-12056T","-12057T","-12058G","-12059T","-12060A","-12061T","-12062C","-12063T","-12064A","-12065T","-12066A","-12067A","-12068T","-12069C","-12070A","-12071C","-12072T","-12073A","-12074T","-12075T","-12076T","-12077A","-12078G","-12079A","-12080T","-12081A","-12082A","-12083T","-12084C","-12085A","-12086G","-12087C","-12088C","-12089A","-12090T","-12091A","-12092A","-12093T","-12094T","-12095C","-12096C","-12097T","-12098C","-12099G","-12100A","-12101G","-12102T","-12103G","-12104C","-12105A","-12106A","-12107C","-12108A","-12109T","-12110G","-12111T","-12112T","-12113A","-12114G","-12115A","-12116T","-12117C","-12118G","-12119T","-12120C","-12121T","-12122A","-12123T","-12124A","-12125T","-12126A","-12127T","-12128G","-12129A","-12130A","-12131T","-12132A","-12133A","-12134G","-12135C","-12136C","-12137G","-12138T","-12139G","-12140T","-12141T","-12142A","-12143T","-12144C","-12145T","-12146A","-12147T","-12148T","-12149C","-12150C","-12151T","-12152T","-12153T","-12154C","-12155A","-12156T","-12157T","-12158A","-12159A","-12160C","-12161A","-12162A","-12163T","-12164T","-12165T","-12166A","-12167A","-12168C","-12169G","-12170A","-12171T","-12172G","-12173T","-12174C","-12175T","-12176A","-12177T","-12178A","-12179T","-12180C","-12181T","-12182A","-12183T","-12184A","-12185T","-12186G","-12187A","-12188G","-12189A","-12190T","-12191G","-12192A","-12193C","-12194T","-12195T","-12196A","-12197A","-12198T","-12199A","-12200T","-12201A","-12202A","-12203T","-12204A","-12205T","-12206T","-12207G","-12208A","-12209A","-12210G","-12211A","-12212G","-12213C","-12214T","-12215G","-12216T","-12217A","-12218C","-12219A","-12220A","-12221T","-12222A","-12223G","-12224T","-12225T","-12226T","-12227T","-12228T","-12229A","-12230T","-12231C","-12232T","-12233A","-12234T","-12235A","-12236G","-12237A","-12238A","G40242A","C40335T","C127609T","G139582A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG023":["-222S","-223I","-224D","-225K","-226N","-227Y","-228C","-229T","-230A","-231L","-232Q","-233Y","-234Y","-235I","-236K","-237S","-238S","-239H","-240I","-241D","-242I","-243D","-244I","-245V","-246K","-247L","-248L","-249M","-250K","-251G","-252I","-253D","-254N","-255T","-256A","-257Y","-258S","-259Y","-260I","-261D","-262D","-263L","-264T","-265C","-266C","-267T","-268R","-269G","-270I","-271M","-272A","-273D","-274Y","-275L","-276N","-277S","-278D","-279Y","-280R","-281Y","-282N","-283K","-284D","-285V","-286D","-287L","-288D","-289L","-290V","-291K","-292L","-293F","-294L","-295E","-296N","-297G","-298K","-299P","-300Y","-301G","-302I","-303M","-304C","-305S","-306I","-307V","-308P","-309L","-310W","-311R","-312N","-313D","-314K","-315E","-316T","-317I","-318S","-319L","-320I","-321L","-322K","-323T","-324M","-325N","-326S","-327D","-328V","-329L","-330Q","-331H","-332I","-333L","-334I","-335E","-336Y","-337M","-338T","-339F","-340G","-341D","-342I","-343D","-344I","-345P","-346L","-347V","-348E","-349C","-350M","-351L","-352E","-353Y","-354G","-355A","-356V","-357V","-358N","-359K","-360E","-361A","-362I","-363H","-364R","-365Y","-366F","-367R","-368N","-369I","-370N","-371I","-372D","-373S","-374Y","-375T","-376M","-377K","-378Y","-379L","-380L","-381K","-382K","-383E","-384G","-385G","-386D","-387A","-388V","-389N","-390H","-391L","-392D","-393D","-394G","-395E","-396I","-397P","-398I","-399G","-400H","-401L","-402C","-403E","-404S","-405N","-406Y","-407G","-408C","-409Y","-410N","-411F","-412Y","-413T","-414Y","-415T","-416Y","-417K","-418K","-419G","-420L","-421C","-422D","-423M","-424S","-425Y","-426V","-427C","-428P","-429I","-430L","-431S","-432T","-433I","-434N","-435I","-436C","-437L","-438P","-439Y","-440L","-441K","-442D","-443I","-444N","-445M","-446I","-447D","-448K","-449R","-450G","-451E","-452T","-453L","-454L","-455H","-456K","-457A","-458V","-459R","-460Y","-461N","-462K","-463Q","-464S","-465L","-466V","-467S","-468L","-469L","-470L","-471E","-472S","-473G","-474S","-475D","-476V","-477N","-478I","-479R","-480S","-481N","-482N","-483G","-484Y","-485T","-486C","-487I","-488T","-489I","-490A","-491I","-492N","-493E","-494S","-495R","-496N","-497I","-498E","-499L","-500L","-501K","-502M","-503L","-504L","-505C","-506H","-507K","-508P","-509T","-510L","-511D","-512C","-513V","-514I","-515D","-516S","-517L","-518S","-519E","-520V","-521S","-522N","-523I","-524V","-525D"],"OPG058":["E34K"]},"labels":{"aa":"OPG023: -222S, -223I, -224D, -225K, -226N, -227Y, -228C, -229T, -230A, -231L, -232Q, -233Y, -234Y, -235I, -236K, -237S, -238S, -239H, -240I, -241D, -242I, -243D, -244I, -245V, -246K, -247L, -248L, -249M, -250K, -251G, -252I, -253D, -254N, -255T, -256A, -257Y, -258S, -259Y, -260I, -261D, -262D, -263L, -264T, -265C, -266C, -267T, -268R, -269G, -270I, -271M, -272A, -273D, -274Y, -275L, -276N, -277S, -278D, -279Y, -280R, -281Y, -282N, -283K, -284D, -285V, -286D, -287L, -288D, -289L, -290V, -291K, -292L, -293F, -294L, -295E, -296N, -297G, -298K, -299P, -300Y, -301G, -302I, -303M, -304C, -305S, -306I, -307V, -308P, -309L, -310W, -311R, -312N, -313D, -314K, -315E, -316T, -317I, -318S, -319L, -320I, -321L, -322K, -323T, -324M, -325N, -326S, -327D, -328V, -329L, -330Q, -331H, -332I, -333L, -334I, -335E, -336Y, -337M, -338T, -339F, -340G, -341D, -342I, -343D, -344I, -345P, -346L, -347V, -348E, -349C, -350M, -351L, -352E, -353Y, -354G, -355A, -356V, -357V, -358N, -359K, -360E, -361A, -362I, -363H, -364R, -365Y, -366F, -367R, -368N, -369I, -370N, -371I, -372D, -373S, -374Y, -375T, -376M, -377K, -378Y, -379L, -380L, -381K, -382K, -383E, -384G, -385G, -386D, -387A, -388V, -389N, -390H, -391L, -392D, -393D, -394G, -395E, -396I, -397P, -398I, -399G, -400H, -401L, -402C, -403E, -404S, -405N, -406Y, -407G, -408C, -409Y, -410N, -411F, -412Y, -413T, -414Y, -415T, -416Y, -417K, -418K, -419G, -420L, -421C, -422D, -423M, -424S, -425Y, -426V, -427C, -428P, -429I, -430L, -431S, -432T, -433I, -434N, -435I, -436C, -437L, -438P, -439Y, -440L, -441K, -442D, -443I, -444N, -445M, -446I, -447D, -448K, -449R, -450G, -451E, -452T, -453L, -454L, -455H, -456K, -457A, -458V, -459R, -460Y, -461N, -462K, -463Q, -464S, -465L, -466V, -467S, -468L, -469L, -470L, -471E, -472S, -473G, -474S, -475D, -476V, -477N, -478I, -479R, -480S, -481N, -482N, -483G, -484Y, -485T, -486C, -487I, -488T, -489I, -490A, -491I, -492N, -493E, -494S, -495R, -496N, -497I, -498E, -499L, -500L, -501K, -502M, -503L, -504L, -505C, -506H, -507K, -508P, -509T, -510L, -511D, -512C, -513V, -514I, -515D, -516S, -517L, -518S, -519E, -520V, -521S, -522N, -523I, -524V, -525D; OPG058: E34K"}},"children":[{"name":"OP819950","node_attrs":{"div":70,"accession":"OP819950","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.15"},"strain":{"value":"MET_INS_MPX_0956_C"},"date":{"value":"2022-10-12"},"strain_display":{"value":"Colombia/OP819950/2022-10-12"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G144284A","C171808T","G196973-","A196974-","A196975-"],"OPG165":["D257N"],"OPG199":["S274L"]},"labels":{"aa":"OPG165: D257N; OPG199: S274L"}}},{"name":"OP693654","node_attrs":{"div":68,"accession":"OP693654","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.15"},"strain":{"value":"DC_INS_MPX_0722_L"},"date":{"value":"2022-08-23"},"strain_display":{"value":"Colombia/OP693654/2022-08-23"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A2840-","T2841-","C2842-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP959066","node_attrs":{"div":68,"accession":"OP959066","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"lineage":{"value":"B.1.15"},"strain":{"value":"CES-UNIMOL-MPX-202203848-L"},"date":{"value":"2022-09-14"},"strain_display":{"value":"Colombia/OP959066/2022-09-14"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OR035721","node_attrs":{"div":70,"accession":"OR035721","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/UZ_REGA_115"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035721/2022-10-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C21324T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G180556A","T196712-","A196713-","T196714-"]}}},{"name":"OR086972","node_attrs":{"div":73,"accession":"OR086972","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.15"},"strain":{"value":"MPXV/UZ_REGA_163/Belgium/2022"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR086972/2022-07-27"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G31180A","C142626T","G158549A","G159341A","C170750T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG163":["S142L"],"OPG185":["G142E"],"OPG198":["A238V"]},"labels":{"aa":"OPG163: S142L; OPG185: G142E; OPG198: A238V"}}}]}]},{"name":"NODE_0000072","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["G175093A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG204":["D188N"]},"labels":{"aa":"OPG204: D188N","clade":"B.1.13"}},"children":[{"name":"OP536663","node_attrs":{"div":64,"accession":"OP536663","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV-USA-IL-IDPH-002"},"date":{"value":"2022-08-04"},"strain_display":{"value":"USA/OP536663/2022-08-04"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G119424A","G125452A","-196615A","-196616A","-196617A"],"OPG136":["S55L"],"OPG146":["S63L"]},"labels":{"aa":"OPG136: S55L; OPG146: S63L"}}},{"name":"NODE_0000073","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["G22814A","G55162A","C118921T","G137128A","G167910A","A173316-","T173317-"],"OPG038":["H116Y"],"OPG074":["S655L"],"OPG136":["D223N"],"OPG193":["E193K"]},"labels":{"aa":"OPG038: H116Y; OPG074: S655L; OPG136: D223N; OPG193: E193K"}},"children":[{"name":"OQ320456","node_attrs":{"div":67,"accession":"OQ320456","author":{"author":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y.","value":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV_USA_2022_KS0004"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ320456/2022-10-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OQ721921","node_attrs":{"div":68,"accession":"OQ721921","author":{"author":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y.","value":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV_USA_2022_KS0005"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721921/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C110297T","A173314-","T173315-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-"]}}}]},{"name":"NODE_0000074","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["C132520T"]}},"children":[{"name":"OP257254","node_attrs":{"div":63,"accession":"OP257254","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.13"},"strain":{"value":"MpxV/human/USA/OH-UW-073812/2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP257254/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP536733","node_attrs":{"div":63,"accession":"OP536733","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV-USA-IL-IDPH-072"},"date":{"value":"2022-06-30"},"strain_display":{"value":"USA/OP536733/2022-06-30"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-196615A","-196616A","-196617A"]}}},{"name":"OP451003","node_attrs":{"div":65,"accession":"OP451003","author":{"author":"Gigante,C.M.,Wang,X.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Ostadkar,R.,Li,Y.","value":"Gigante,C.M.,Wang,X.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Ostadkar,R.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV_USA_2022_MN0006"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OP451003/2022-07-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","G127678A","G165086A","G173341-","A173342-","A173343-","T173344-","T173345-","A173346-","T173347-","A173348-","A173349-","A173350-","A173351-","T173352-","T173353-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"],"OPG149":["M161I"]},"labels":{"aa":"OPG149: M161I"}}},{"name":"NODE_0000075","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["C21383T","G85431A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG037":["G351S"],"OPG106":["S23F"]},"labels":{"aa":"OPG037: G351S; OPG106: S23F"}},"children":[{"name":"OP270476","node_attrs":{"div":66,"accession":"OP270476","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Friesen,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Friesen,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV/Germany/2022/RKI287"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP270476/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C172851T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-"]}}},{"name":"OQ773520","node_attrs":{"div":67,"accession":"OQ773520","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.13"},"strain":{"value":"MPXV/Germany/2022/ON/RKI901"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773520/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C146446T","C147140T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG170":["M111I"]},"labels":{"aa":"OPG170: M111I"}}}]},{"name":"NODE_0000076","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.13"}},"branch_attrs":{"mutations":{"nuc":["G99832A","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"],"OPG118":["D463N"]},"labels":{"aa":"OPG118: D463N"}},"children":[{"name":"OP743957","node_attrs":{"div":67,"accession":"OP743957","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.13"},"strain":{"value":"MpxV/human/USA/OH-UW-080634/2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP743957/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C16327T","G61713A","G135355A"]}}},{"name":"OR160418","node_attrs":{"div":70,"accession":"OR160418","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"lineage":{"value":"B.1.13"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-052-0034/2023"},"date":{"value":"2023-05-10"},"strain_display":{"value":"USA/OR160418/2023-05-10"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C27520T","G58883A","G102186A","G129583A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G171410A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C182950T"],"OPG043":["A146T"],"OPG121":["E133K"],"OPG210":["S532L"]},"labels":{"aa":"OPG043: A146T; OPG121: E133K; OPG210: S532L"}}}]}]}]},{"name":"NODE_0000077","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.6"}},"branch_attrs":{"mutations":{"nuc":["G111029A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]},"labels":{"clade":"B.1.6"}},"children":[{"name":"OP289782","node_attrs":{"div":62,"accession":"OP289782","author":{"author":"Silva,I.,Jimenez,V.,Hurtado,V.,Barcena,L.","value":"Silva,I.,Jimenez,V.,Hurtado,V.,Barcena,L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Peru"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"lineage":{"value":"B.1.6"},"strain":{"value":"LIM-INS-001"},"date":{"value":"2022-06-25"},"strain_display":{"value":"Peru/OP289782/2022-06-25"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-196615A","-196616A","-196617A"]}}},{"name":"OP431402","node_attrs":{"div":63,"accession":"OP431402","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.6"},"strain":{"value":"ANT-LDSP-ANT-MPX-22752-O"},"date":{"value":"2022-08-18"},"strain_display":{"value":"Colombia/OP431402/2022-08-18"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G15814A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP536765","node_attrs":{"div":64,"accession":"OP536765","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.6"},"strain":{"value":"9000387"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP536765/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G59112A","C87978T"]}}},{"name":"OP837474","node_attrs":{"div":63,"accession":"OP837474","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.6"},"strain":{"value":"DC_INS_MPX_0996_L"},"date":{"value":"2022-09-19"},"strain_display":{"value":"Colombia/OP837474/2022-09-19"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G29656A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"],"OPG046":["S25L"]},"labels":{"aa":"OPG046: S25L"}}},{"name":"OQ348868","node_attrs":{"div":64,"accession":"OQ348868","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDPH, VRDL"},"lineage":{"value":"B.1.6"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000120/2022"},"date":{"value":"2022-09-20"},"strain_display":{"value":"USA/OQ348868/2022-09-20"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","G150364A","C166930T"],"OPG176":["E186K"],"OPG192":["S67L"]},"labels":{"aa":"OPG176: E186K; OPG192: S67L"}}},{"name":"OQ503831","node_attrs":{"div":66,"accession":"OQ503831","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.6"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00408/2023"},"date":{"value":"2023-01-11"},"strain_display":{"value":"USA/OQ503831/2023-01-11"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","G10945A","G39515A","C44627T","G56276A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A196614-"],"OPG064":["M424I"]},"labels":{"aa":"OPG064: M424I"}}},{"name":"OP320555","node_attrs":{"div":62,"accession":"OP320555","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Peru"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"lineage":{"value":"B.1.6"},"strain":{"value":"LIM-INS-021"},"date":{"value":"2022-07-09"},"strain_display":{"value":"Peru/OP320555/2022-07-09"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP289783","node_attrs":{"div":62,"accession":"OP289783","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Mestanza,O.,Lope,P.,Nunez,A.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Mestanza,O.,Lope,P.,Nunez,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Peru"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"lineage":{"value":"B.1.6"},"strain":{"value":"LIM-INS-003"},"date":{"value":"2022-06-27"},"strain_display":{"value":"Peru/OP289783/2022-06-27"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000079","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.6"}},"branch_attrs":{"mutations":{"nuc":["C14098T","C84063T","G142493A","G151324A","C170573T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C187332T","C196696-","G196697-","A196698-"],"OPG163":["D98N"],"OPG198":["S179L"]},"labels":{"aa":"OPG163: D98N; OPG198: S179L"}},"children":[{"name":"OQ331003","node_attrs":{"div":70,"accession":"OQ331003","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.6"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00392/2022"},"date":{"value":"2022-12-06"},"strain_display":{"value":"USA/OQ331003/2022-12-06"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G97749A","G188726A"]}}},{"name":"OR499960","node_attrs":{"div":74,"accession":"OR499960","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1.6"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00503/2023"},"date":{"value":"2023-03-15"},"strain_display":{"value":"USA/OR499960/2023-03-15"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G6746A","C39266T","C63819T","G106927A","G138862A","G169213A"],"OPG083":["V300I"],"OPG125":["T243M"],"OPG156":["S183F"]},"labels":{"aa":"OPG083: V300I; OPG125: T243M; OPG156: S183F"}}}]},{"name":"NODE_0000080","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.6"}},"branch_attrs":{"mutations":{"nuc":["G63811A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G167862A","C170130T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179266-","T179267-","A179270-","T179271-","A179272-","T179273-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","A179282-"],"OPG193":["D177N"]},"labels":{"aa":"OPG193: D177N"}},"children":[{"name":"OQ696099","node_attrs":{"div":66,"accession":"OQ696099","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.6"},"strain":{"value":"ANT-LDSP-ANT-MPX-30518C"},"date":{"value":"2022-11-09"},"strain_display":{"value":"Colombia/OQ696099/2022-11-09"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G132863A","-179266A","-179267T","-179270A","-179271T","-179272A","-179273T","-179275T","-179276T","-179277T","-179278A","-179279A","-179280A","-179282A"]}}},{"name":"OQ696077","node_attrs":{"div":65,"accession":"OQ696077","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.6"},"strain":{"value":"ANT-LDSP-ANT-MPX-29396O"},"date":{"value":"2022-10-27"},"strain_display":{"value":"Colombia/OQ696077/2022-10-27"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179265-","G179268-","G179269-","C179274-","G179281-"]}}}]}]},{"name":"NODE_0000081","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["G9963A","T133102-","C148268T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG021":["R126K"]},"labels":{"aa":"OPG021: R126K","clade":"B.1.19"}},"children":[{"name":"OP270026","node_attrs":{"div":63,"accession":"OP270026","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.19"},"strain":{"value":"MpxV/human/CAN/UN-NML-4017/2022"},"date":{"value":"2022-07-05"},"strain_display":{"value":"Canada/OP270026/2022-07-05"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-133102T","-196615A","-196616A","-196617A"]}}},{"name":"OP382481","node_attrs":{"div":65,"accession":"OP382481","author":{"author":"Colson,P.","value":"Colson,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"lineage":{"value":"B.1.19"},"strain":{"value":"hMPXV-IHU00004"},"date":{"value":"2022-07-04"},"strain_display":{"value":"France/OP382481/2022-07-04"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G115549A","C163653T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"],"OPG133":["P50S"]},"labels":{"aa":"OPG133: P50S"}}},{"name":"OP838893","node_attrs":{"div":63,"accession":"OP838893","author":{"author":"Viscardi,M.,Cozzolino,L.,De Martinis,C.,Cardillo,L.,Fusco,G.","value":"Viscardi,M.,Cozzolino,L.,De Martinis,C.,Cardillo,L.,Fusco,G."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Italy"},"clade_membership":{"value":"IIb"},"institution":{"value":"Istituto Zooprofilattico Sperimentale del Mezzogiorno, Hanimal Health"},"lineage":{"value":"B.1.19"},"strain":{"value":"ID6821"},"date":{"value":"2022-06-21"},"strain_display":{"value":"Italy/OP838893/2022-06-21"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","T133100-","T133101-","C133103-","G133104-","A133105-","A133106-","T133107-","T133108-","C133109-","A133110-","C133111-","G133112-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A157678-","A157679-","A157680-","A157681-","T157682-","T157683-","T157684-","T157685-","A157686-","A157687-","G157688-","C157689-","G157690-","A157691-","T157692-","G157693-","A157694-","T157695-","A157696-","T163214-","C163215-","T163216-","T163217-","A163218-","T163219-","A163220-","T163221-","A163417-","A163418-","T163419-","T163420-","C163421-","T163422-","T163423-","C163424-","C163425-","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","G174537-","A174538-","T174539-","G174540-","A174541-","A174542-","A180482-","T180483-","T180484-","A180485-","A180486-","A180487-","A180488-","A180489-","A181114-","T181115-","T181116-","C181117-","C181118-","T181119-","T181120-","A181121-","T181122-","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-"],"OPG159":["N124-","Y125-","N126-"],"OPG189":["N29-","S30-","S31-"]},"labels":{"aa":"OPG159: N124-, Y125-, N126-; OPG189: N29-, S30-, S31-"}}},{"name":"OR035726","node_attrs":{"div":65,"accession":"OR035726","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV/UZ_REGA_120"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035726/2022-10-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C22739T","-133102T","G133104A","G133231A","T137560-","G164487A"],"OPG038":["E141K"]},"labels":{"aa":"OPG038: E141K"}}},{"name":"OR086965","node_attrs":{"div":68,"accession":"OR086965","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV/UZ_REGA_156/Belgium/2022"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR086965/2022-07-27"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C71016T","G77415A","T133101-","G133319A","C176069T","G181309A"],"OPG089":["S384L"]},"labels":{"aa":"OPG089: S384L"}}},{"name":"NODE_0000082","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["G150003A","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"]}},"children":[{"name":"OQ172215","node_attrs":{"div":68,"accession":"OQ172215","author":{"author":"Zeggagh,J.,Ferraris,O.,Salmona,M.,Tarantola,A.,Molina,J.M.,Delaugerre,C.","value":"Zeggagh,J.,Ferraris,O.,Salmona,M.,Tarantola,A.,Molina,J.M.,Delaugerre,C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"Hopital Saint Louis, Paris"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV-1047"},"date":{"value":"2022-06-07"},"strain_display":{"value":"France/OQ172215/2022-06-07"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A2591G","A31053G","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133171-","C133172-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T133639-","A150635-","A152676-","T152686-","T155897A","C173533A","A179077T","A179079T","A179081T","C179082T","A179083T","A179086T","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","T194619C","T194627G"],"OPG002":["F54S"],"OPG002_dup":["F54S","C57G"],"OPG047":["C48R"]},"labels":{"aa":"OPG002: F54S; OPG002_dup: F54S, C57G; OPG047: C48R"}}},{"name":"OQ427121","node_attrs":{"div":65,"accession":"OQ427121","author":{"author":"Gigante,C.,Cogswell,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Grenz,L.,Li,Y.","value":"Gigante,C.,Cogswell,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Grenz,L.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV_USA_2022_OR0008"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OQ427121/2022-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-133102T","C150140T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"],"OPG176":["S111L"]},"labels":{"aa":"OPG176: S111L"}}},{"name":"OR095050","node_attrs":{"div":67,"accession":"OR095050","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV/UZ_REGA_232/Belgium/2022"},"date":{"value":"2022-08-12"},"strain_display":{"value":"Belgium/OR095050/2022-08-12"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G57033A","G77415A","G83609A","T133101-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C196750-","T196751-","A196752-"]}}},{"name":"NODE_0000083","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["C74417T","-133102T"],"OPG094":["S213L"]},"labels":{"aa":"OPG094: S213L"}},"children":[{"name":"OP205108","node_attrs":{"div":65,"accession":"OP205108","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV_UK_2022_9000145"},"date":{"value":"2022-06-16"},"strain_display":{"value":"United Kingdom/OP205108/2022-06-16"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP413717","node_attrs":{"div":65,"accession":"OP413717","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.19"},"strain":{"value":"9000353"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP413717/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP536781","node_attrs":{"div":66,"accession":"OP536781","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.19"},"strain":{"value":"9000405"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536781/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","C62868T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"]}}}]},{"name":"NODE_0000084","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["-133102T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A169944T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG197":["E92V"]},"labels":{"aa":"OPG197: E92V"}},"children":[{"name":"OP555622","node_attrs":{"div":65,"accession":"OP555622","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.19"},"strain":{"value":"Monkeypox/PT0551/2022"},"date":{"value":"2022-08-26"},"strain_display":{"value":"Portugal/OP555622/2022-08-26"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000085","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.19"}},"branch_attrs":{"mutations":{"nuc":["C185326T","-196615A"],"OPG210":["S1324L"]},"labels":{"aa":"OPG210: S1324L"}},"children":[{"name":"OP555643","node_attrs":{"div":67,"accession":"OP555643","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.19"},"strain":{"value":"Monkeypox/PT0572/2022"},"date":{"value":"2022-09-05"},"strain_display":{"value":"Portugal/OP555643/2022-09-05"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","C55057T"],"OPG073":["E29K"]},"labels":{"aa":"OPG073: E29K"}}},{"name":"OQ159056","node_attrs":{"div":70,"accession":"OQ159056","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.19"},"strain":{"value":"MPXV/Germany/2022/ON/RKI661"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OQ159056/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C2652T","G9584A","C87741T","G98995A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG002":["D34N"],"OPG118":["E184K"]},"labels":{"aa":"OPG002: D34N; OPG118: E184K"}}}]}]}]}]},{"name":"NODE_0000086","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1"}},"branch_attrs":{"mutations":{"nuc":["-607T","G53326A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-196615A"]}},"children":[{"name":"OR264430","node_attrs":{"div":64,"accession":"OR264430","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1"},"strain":{"value":"51_B"},"date":{"value":"2022-09-05"},"strain_display":{"value":"Australia/OR264430/2022-09-05"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C15582T","C121104T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG138":["R10K"]},"labels":{"aa":"OPG138: R10K"}}},{"name":"NODE_0000087","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["T133102-","C164385T","C187620T"]},"labels":{"clade":"B.1.20"}},"children":[{"name":"OQ320441","node_attrs":{"div":64,"accession":"OQ320441","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV_USA_2022_TX0040"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ320441/2022-10-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"]}}},{"name":"OQ054239","node_attrs":{"div":65,"accession":"OQ054239","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV_USA_2022_TX0017"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ054239/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-133102T","G176549A","-179194A","-179195T","-179196A","-179197T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG205":["M298I"]},"labels":{"aa":"OPG205: M298I"}}},{"name":"OQ427125","node_attrs":{"div":66,"accession":"OQ427125","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV_USA_2022_TX0044"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ427125/2022-10-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G48645A","G130027A","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-"],"OPG068":["E149K"]},"labels":{"aa":"OPG068: E149K"}}},{"name":"NODE_0000088","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["T602-","T603-","T604-","T605-","T606-","T607-","-133102T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177398A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A196610-","A196611-","A196612-","A196613-","A196614-","A196615-"]}},"children":[{"name":"OQ918695","node_attrs":{"div":65,"accession":"OQ918695","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00484/2023"},"date":{"value":"2023-02-07"},"strain_display":{"value":"USA/OQ918695/2023-02-07"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ644783","node_attrs":{"div":65,"accession":"OQ644783","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00477/2023"},"date":{"value":"2023-01-17"},"strain_display":{"value":"USA/OQ644783/2023-01-17"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T179179-","A179180-"]}}},{"name":"NODE_0000089","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["G36027A","C72221T","A150586-","T150587-","A150588-","T150589-","A150591-","T150592-","A150595-","T150596-","A150597-","T150598-","A150600-","T150601-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A"],"OPG055":["R353C"],"OPG092":["E243K"]},"labels":{"aa":"OPG055: R353C; OPG092: E243K"}},"children":[{"name":"OQ427126","node_attrs":{"div":67,"accession":"OQ427126","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV_USA_2022_TX0045"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"USA/OQ427126/2022-11-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-"]}}},{"name":"OQ626773","node_attrs":{"div":71,"accession":"OQ626773","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV22/human/USA-NE-375"},"date":{"value":"2022-12-28"},"strain_display":{"value":"USA/OQ626773/2022-12-28"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-602T","-603T","-604T","-605T","-606T","-607T","-608T","-609T","C11175A","G102694A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C161572T","G164017A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196610A","-196611A","-196612A","-196613A","-196614A","-196615A","-196616A","-196617A"],"OPG023":["G576*"],"OPG189":["E229K"]},"labels":{"aa":"OPG023: G576*; OPG189: E229K"}}}]},{"name":"NODE_0000090","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["C177899T","T179179-","A179180-"]}},"children":[{"name":"OR499966","node_attrs":{"div":67,"accession":"OR499966","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00509/2023"},"date":{"value":"2023-03-31"},"strain_display":{"value":"USA/OR499966/2023-03-31"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G115293A"],"OPG133":["A135V"]},"labels":{"aa":"OPG133: A135V"}}},{"name":"NODE_0000091","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["C20453T","T164946C"]}},"children":[{"name":"OR449306","node_attrs":{"div":68,"accession":"OR449306","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Germany/2023/RKI1020"},"date":{"value":"2023-07-XX"},"strain_display":{"value":"Germany/OR449306/2023-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-602T","-603T","-604T","-605T","-606T","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"]}}},{"name":"OR421480","node_attrs":{"div":68,"accession":"OR421480","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"lineage":{"value":"B.1.20"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0023/2023"},"date":{"value":"2023-05-07"},"strain_display":{"value":"USA/OR421480/2023-05-07"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OR500001","node_attrs":{"div":69,"accession":"OR500001","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00545/2023"},"date":{"value":"2023-06-10"},"strain_display":{"value":"USA/OR500001/2023-06-10"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C2313T","G194897A"],"OPG002":["D147N"],"OPG002_dup":["D147N"]},"labels":{"aa":"OPG002: D147N; OPG002_dup: D147N"}}},{"name":"OR499954","node_attrs":{"div":68,"accession":"OR499954","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"B.1.20"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00497/2023"},"date":{"value":"2023-04-28"},"strain_display":{"value":"USA/OR499954/2023-04-28"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000092","node_attrs":{"div":70,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.20"}},"branch_attrs":{"mutations":{"nuc":["-604T","-605T","-606T","C174050T","C180618T"],"OPG209":["S34L"]},"labels":{"aa":"OPG209: S34L"}},"children":[{"name":"OR725698","node_attrs":{"div":72,"accession":"OR725698","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"lineage":{"value":"B.1.20"},"strain":{"value":"hMpxV/USA/IL-RIPHL-052-0100/2023"},"date":{"value":"2023-08-22"},"strain_display":{"value":"USA/OR725698/2023-08-22"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C105798T","G148126A"]}}},{"name":"OR725697","node_attrs":{"div":72,"accession":"OR725697","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"lineage":{"value":"B.1.20"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0107/2023"},"date":{"value":"2023-09-06"},"strain_display":{"value":"USA/OR725697/2023-09-06"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","G113508A","C136791T"],"OPG153":["E293K"]},"labels":{"aa":"OPG153: E293K"}}},{"name":"OR473619","node_attrs":{"div":72,"accession":"OR473619","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"lineage":{"value":"B.1.20"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0088/2023"},"date":{"value":"2023-07-17"},"strain_display":{"value":"USA/OR473619/2023-07-17"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C61724T","C111728T"],"OPG080":["E99K"],"OPG130":["D59N"]},"labels":{"aa":"OPG080: E99K; OPG130: D59N"}}}]}]}]}]}]}]},{"name":"NODE_0000093","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["C18133T","G67611A","G130231A","G159277A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179217C","-179226C","-179235C"],"OPG185":["E121K"]},"labels":{"aa":"OPG185: E121K","clade":"B.1.11"}},"children":[{"name":"OP169336","node_attrs":{"div":65,"accession":"OP169336","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.11"},"strain":{"value":"MpxV/human/USA/WA-UW-070499/2022"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OP169336/2022-07-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OP390178","node_attrs":{"div":65,"accession":"OP390178","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"lineage":{"value":"B.1.11"},"strain":{"value":"MAG-UNIMOL-MPX-292982-L"},"date":{"value":"2022-08-20"},"strain_display":{"value":"Colombia/OP390178/2022-08-20"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP555545","node_attrs":{"div":65,"accession":"OP555545","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.11"},"strain":{"value":"Monkeypox/PT0466/2022"},"date":{"value":"2022-08-05"},"strain_display":{"value":"Portugal/OP555545/2022-08-05"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","C179217-","C179226-","C179235-"]}}},{"name":"OP536702","node_attrs":{"div":65,"accession":"OP536702","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV-USA-IL-IDPH-041"},"date":{"value":"2022-06-21"},"strain_display":{"value":"USA/OP536702/2022-06-21"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"OP524006","node_attrs":{"div":66,"accession":"OP524006","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV/Germany/2022/RKI404"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP524006/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","C179217-","C179226-","C179235-","G182634A","-196615A"],"OPG210":["D427N"]},"labels":{"aa":"OPG210: D427N"}}},{"name":"OP879738","node_attrs":{"div":65,"accession":"OP879738","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"lineage":{"value":"B.1.11"},"strain":{"value":"NJ-MPXV-020-rep2"},"date":{"value":"2022-07-06"},"strain_display":{"value":"USA/OP879738/2022-07-06"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","C179217-","C179226-","C179235-"]}}},{"name":"OP819960","node_attrs":{"div":68,"accession":"OP819960","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.11"},"strain":{"value":"SAN_INS_MPX_0973_L"},"date":{"value":"2022-10-17"},"strain_display":{"value":"Colombia/OP819960/2022-10-17"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A19748-","G19749-","G19750-","C19751-","G19752-","T19753-","G27840A","C64404T","C96810T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG034":["T87-","P88-"],"OPG043":["S39F"],"OPG083":["D105N"]},"labels":{"aa":"OPG034: T87-, P88-; OPG043: S39F; OPG083: D105N"}}},{"name":"OQ148464","node_attrs":{"div":68,"accession":"OQ148464","author":{"author":"Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"lineage":{"value":"B.1.11"},"strain":{"value":"LBMB-UTP_MP-006_TOL"},"date":{"value":"2022-09-16"},"strain_display":{"value":"Colombia/OQ148464/2022-09-16"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C58682T","C170573T","G178744A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG078":["G44S"],"OPG198":["S179L"]},"labels":{"aa":"OPG078: G44S; OPG198: S179L"}}},{"name":"OP920682","node_attrs":{"div":67,"accession":"OP920682","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00344/2022"},"date":{"value":"2022-11-09"},"strain_display":{"value":"USA/OP920682/2022-11-09"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","G39327A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177273A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","C179217-","C179226-","C179235-","-196615A"],"OPG057":["A290V"],"OPG205":["D540N"]},"labels":{"aa":"OPG057: A290V; OPG205: D540N"}}},{"name":"OR035719","node_attrs":{"div":68,"accession":"OR035719","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV/UZ_REGA_113"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035719/2022-10-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133102-","C142797T","C167995T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G189258A"],"OPG164":["S7L"],"OPG193":["S221F"]},"labels":{"aa":"OPG164: S7L; OPG193: S221F"}}},{"name":"OQ957072","node_attrs":{"div":68,"accession":"OQ957072","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.11"},"strain":{"value":"ANT-LDSP-ANT-MPX-3668E"},"date":{"value":"2023-02-16"},"strain_display":{"value":"Colombia/OQ957072/2023-02-16"},"region":{"value":"South America"}},"branch_attrs":{"mutations":{"nuc":["C35308T","G71777A","C120979T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG054":["R230H"],"OPG138":["D52N"]},"labels":{"aa":"OPG054: R230H; OPG138: D52N"}}},{"name":"OQ696101","node_attrs":{"div":69,"accession":"OQ696101","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.11"},"strain":{"value":"ANT-LDSP-ANT-MPX-30628C"},"date":{"value":"2022-11-11"},"strain_display":{"value":"Colombia/OQ696101/2022-11-11"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G17023A","G74462A","C80742T","G113382A","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG029":["S16F"],"OPG094":["R228K"],"OPG104":["R93Q"]},"labels":{"aa":"OPG029: S16F; OPG094: R228K; OPG104: R93Q"}}},{"name":"OR095053","node_attrs":{"div":65,"accession":"OR095053","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV/UZ_REGA_235/Belgium/2022"},"date":{"value":"2022-08-12"},"strain_display":{"value":"Belgium/OR095053/2022-08-12"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000094","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["-607T","C89777T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG110":["P49L"]},"labels":{"aa":"OPG110: P49L"}},"children":[{"name":"OP628471","node_attrs":{"div":66,"accession":"OP628471","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.11"},"strain":{"value":"MpxV/human/USA/WA-UW-086901/2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP628471/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-196615A"]}}},{"name":"OR433614","node_attrs":{"div":66,"accession":"OR433614","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.11"},"strain":{"value":"MpxV/human/USA/WA-UW-094945/2022"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OR433614/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T166110-","T166111-","A166112-","A166113-","T166114-","A166115-","A166116-"]}}}]},{"name":"NODE_0000095","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.11"}},"branch_attrs":{"mutations":{"nuc":["G19458A","-179194A","-179195T","-179196A","-179197T","-179198A","C179217-","C179226-","C179235-","C185455T"],"OPG034":["S183L"],"OPG210":["S1367L"]},"labels":{"aa":"OPG034: S183L; OPG210: S1367L"}},"children":[{"name":"OQ320458","node_attrs":{"div":69,"accession":"OQ320458","author":{"author":"Gigante,C.,Cleavinger,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Burroughs,M.R.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Sinn,M.,Li,Y.","value":"Gigante,C.,Cleavinger,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Burroughs,M.R.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Sinn,M.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV_USA_2022_MO0002"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ320458/2022-10-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","G149818A","T167929A","A196614-"],"OPG176":["D4N"],"OPG193":["I199N"]},"labels":{"aa":"OPG176: D4N; OPG193: I199N"}}},{"name":"OR209310","node_attrs":{"div":68,"accession":"OR209310","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.11"},"strain":{"value":"MPXV_USA_2022_TX0052"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR209310/2022-12-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G74374A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A"],"OPG094":["E199K"]},"labels":{"aa":"OPG094: E199K"}}}]}]},{"name":"NODE_0000096","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["G36617A","C159779T"],"OPG055":["S156L"],"OPG185":["S288L"]},"labels":{"aa":"OPG055: S156L; OPG185: S288L","clade":"B.1.14"}},"children":[{"name":"ON694342","node_attrs":{"div":63,"accession":"ON694342","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/RKI011"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/ON694342/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP378704","node_attrs":{"div":66,"accession":"OP378704","author":{"author":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y.","value":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV_USA_2022_TX0010"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP378704/2022-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C8552T","C8597T","G46179A","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A","-196616A"],"OPG065":["S102L"]},"labels":{"aa":"OPG065: S102L"}}},{"name":"OP355563","node_attrs":{"div":63,"accession":"OP355563","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/ON/RKI302"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP355563/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","A188351-"]}}},{"name":"OP837348","node_attrs":{"div":67,"accession":"OP837348","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/RKI586"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OP837348/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C2459T","G90418A","C133943T","C134688T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G194751A"],"OPG002":["R98Q"],"OPG002_dup":["R98Q"],"OPG111":["E52K"]},"labels":{"aa":"OPG002: R98Q; OPG002_dup: R98Q; OPG111: E52K"}}},{"name":"OQ547749","node_attrs":{"div":63,"accession":"OQ547749","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/ON/RKI722"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ547749/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150563-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OR086995","node_attrs":{"div":64,"accession":"OR086995","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/UZ_REGA_186/Belgium/2022"},"date":{"value":"2022-08-03"},"strain_display":{"value":"Belgium/OR086995/2022-08-03"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G146441A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG170":["S113F"]},"labels":{"aa":"OPG170: S113F"}}},{"name":"OX009124","node_attrs":{"div":65,"accession":"OX009124","author":{"author":"Pettke,A.,Filen,F.,Asgeirsson,H.,Glans,H.,Widgren,K.,Muradrasoli,S.,Helgesson,S.,Karlberg,M.L.,Walai,N.,Bjerkner,A.,Gourle,H.,Lindsjo,O.K.,Sonden,K.","value":"Pettke,A.,Filen,F.,Asgeirsson,H.,Glans,H.,Widgren,K.,Muradrasoli,S.,Helgesson,S.,Karlberg,M.L.,Walai,N.,Bjerkner,A.,Gourle,H.,Lindsjo,O.K.,Sonden,K."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Sweden"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Agency of Sweden, Unit for Laboratory Development and Technology Transfer , Folkhalsomyndigheten, 171 82 Solna"},"lineage":{"value":"B.1.14"},"strain":{"value":"Lesion"},"date":{"value":"2022-05-22"},"strain_display":{"value":"Sweden/OX009124/2022-05-22"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T602-","T603-","T604-","T605-","T606-","A8055-","A28529-","A28530-","T47054-","T76087-","T88836-","A91705-","A92907-","T103367-","T104687-","T148344A","A148345T","A151680-","A162904-","T163342-","T163597-","A170728-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG044":["K147-"],"OPG113":["I393-"],"OPG178":["T58-"],"OPG188":["K437-"],"OPG189":["F4-"],"OPG198":["K231-"]},"labels":{"aa":"OPG044: K147-; OPG113: I393-; OPG178: T58-; OPG188: K437-; OPG189: F4-; OPG198: K231-"}}},{"name":"ON959133","node_attrs":{"div":63,"accession":"ON959133","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV_USA_2022_NY002"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/ON959133/2022-05-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"]}}},{"name":"OP451009","node_attrs":{"div":63,"accession":"OP451009","author":{"author":"Gigante,C.M.,Pearson,C.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Maloney,M.,Li,Y.","value":"Gigante,C.M.,Pearson,C.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Maloney,M.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV_USA_2022_CT0002"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OP451009/2022-07-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","T173277-","A173278-","T173279-","A173280-","T173281-","A173282-","T173283-","A173284-","T173285-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"]}}},{"name":"NODE_0000098","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["G158617A","C183790T"],"OPG210":["S812L"]},"labels":{"aa":"OPG210: S812L"}},"children":[{"name":"ON929060","node_attrs":{"div":67,"accession":"ON929060","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/RKI102"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/ON929060/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C127245T","C132437T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG149":["S17L"]},"labels":{"aa":"OPG149: S17L"}}},{"name":"OR035646","node_attrs":{"div":67,"accession":"OR035646","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/UZ_REGA_40"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR035646/2022-07-27"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C22880T","C170573T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG038":["E94K"],"OPG198":["S179L"]},"labels":{"aa":"OPG038: E94K; OPG198: S179L"}}}]},{"name":"NODE_0000099","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["G28021A"]}},"children":[{"name":"OP539922","node_attrs":{"div":66,"accession":"OP539922","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00137/2022"},"date":{"value":"2022-08-09"},"strain_display":{"value":"USA/OP539922/2022-08-09"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G109793A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G168211-","G168212-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G181818A"],"OPG210":["A155T"]},"labels":{"aa":"OPG210: A155T"}}},{"name":"OR026632","node_attrs":{"div":68,"accession":"OR026632","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Utah Public Health Laboratory, Utah Public Health Laboratory Infectious Disease submission group"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200396/2022"},"date":{"value":"2022-09-19"},"strain_display":{"value":"USA/OR026632/2022-09-19"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C25855T","G127941A","C177833T","C177917T"],"OPG042":["E415K"],"OPG150":["D55N"]},"labels":{"aa":"OPG042: E415K; OPG150: D55N"}}}]},{"name":"NODE_0000100","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.14"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G171270A","-196615A"],"OPG199":["D95N"]},"labels":{"aa":"OPG199: D95N"}},"children":[{"name":"OP382492","node_attrs":{"div":65,"accession":"OP382492","author":{"author":"Colson,P.","value":"Colson,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"lineage":{"value":"B.1.14"},"strain":{"value":"hMPXV-IHU00015"},"date":{"value":"2022-07-22"},"strain_display":{"value":"France/OP382492/2022-07-22"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","T607-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G161913A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196856-","A196857-","A196858-"]}}},{"name":"OP494266","node_attrs":{"div":64,"accession":"OP494266","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.14"},"strain":{"value":"MPXV/Germany/2022/ON/RKI320"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP494266/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T607-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OP605553","node_attrs":{"div":64,"accession":"OP605553","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"lineage":{"value":"B.1.14"},"strain":{"value":"Slovenia-MPXV-10-2022"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Slovenia/OP605553/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T594A","-608T","-609T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","T196950-","A196951-","A196952-"]}}},{"name":"OP555644","node_attrs":{"div":66,"accession":"OP555644","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.14"},"strain":{"value":"Monkeypox/PT0573/2022"},"date":{"value":"2022-09-06"},"strain_display":{"value":"Portugal/OP555644/2022-09-06"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T594A","-608T","-609T","C93713T","G158549A","-196616T"]}}},{"name":"OP555575","node_attrs":{"div":64,"accession":"OP555575","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.14"},"strain":{"value":"Monkeypox/PT0501/2022"},"date":{"value":"2022-08-16"},"strain_display":{"value":"Portugal/OP555575/2022-08-16"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000101","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["G34308A"],"OPG053":["S128L"]},"labels":{"aa":"OPG053: S128L","clade":"B.1.4"}},"children":[{"name":"OP390177","node_attrs":{"div":63,"accession":"OP390177","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"lineage":{"value":"B.1.4"},"strain":{"value":"ATL-UNIMOL-MPX-292896-L"},"date":{"value":"2022-08-13"},"strain_display":{"value":"Colombia/OP390177/2022-08-13"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C176447T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"NODE_0000102","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["T85846C"],"OPG107":["M112T"]},"labels":{"aa":"OPG107: M112T"}},"children":[{"name":"ON880519","node_attrs":{"div":63,"accession":"ON880519","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-2833/2022"},"date":{"value":"2022-05-13"},"strain_display":{"value":"Canada/ON880519/2022-05-13"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"ON880532","node_attrs":{"div":63,"accession":"ON880532","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-3253/2022"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Canada/ON880532/2022-05-30"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C133187-","A133188-","T133189-","T133190-","T133191-","C133192-","A133193-"]}}}]},{"name":"NODE_0000103","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["C10672T","G112481A","G163626A"],"OPG022":["E63K"]},"labels":{"aa":"OPG022: E63K"}},"children":[{"name":"OR126132","node_attrs":{"div":69,"accession":"OR126132","author":{"author":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C.","value":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Spain"},"clade_membership":{"value":"IIb"},"institution":{"value":"Hospital Ramon y Cajal, Microbiology"},"lineage":{"value":"B.1.4"},"strain":{"value":"HRYC_MPXV002"},"date":{"value":"2023-03-23"},"strain_display":{"value":"Spain/OR126132/2023-03-23"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G6376A","G11924A","G21674A","A87705G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C190834T"],"OPG016":["S142L"],"OPG023":["S326L"],"OPG037":["L254F"]},"labels":{"aa":"OPG016: S142L; OPG023: S326L; OPG037: L254F"}}},{"name":"NODE_0000104","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["G144478A"]}},"children":[{"name":"ON880511","node_attrs":{"div":66,"accession":"ON880511","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-3214/2022"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Canada/ON880511/2022-05-30"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP484341","node_attrs":{"div":69,"accession":"OP484341","author":{"author":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T.","value":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPXV22/human/USA-OK-180"},"date":{"value":"2022-08-17"},"strain_display":{"value":"USA/OP484341/2022-08-17"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G84534A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G175117A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G185991A","-196615A","-196616A","-196617A"],"OPG105":["D1137N"],"OPG204":["D196N"],"OPG210":["D1546N"]},"labels":{"aa":"OPG105: D1137N; OPG204: D196N; OPG210: D1546N"}}}]}]},{"name":"NODE_0000105","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["C24995T","G85774A","G148427A","G189258A"],"OPG040":["D162N"],"OPG107":["R88K"]},"labels":{"aa":"OPG040: D162N; OPG107: R88K"}},"children":[{"name":"ON983163","node_attrs":{"div":66,"accession":"ON983163","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-3532/2022"},"date":{"value":"2022-06-07"},"strain_display":{"value":"Canada/ON983163/2022-06-07"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"ON880515","node_attrs":{"div":66,"accession":"ON880515","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-3467/2022"},"date":{"value":"2022-06-02"},"strain_display":{"value":"Canada/ON880515/2022-06-02"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP415246","node_attrs":{"div":68,"accession":"OP415246","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPX_J6xzTO_9000286"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415246/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G45236A","G174962A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG204":["R144K"]},"labels":{"aa":"OPG204: R144K"}}},{"name":"NODE_0000106","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["C13331T","G67225A"],"OPG085":["S436L"]},"labels":{"aa":"OPG085: S436L"}},"children":[{"name":"OP279037","node_attrs":{"div":68,"accession":"OP279037","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/CAN/UN-NML-4113/2022"},"date":{"value":"2022-07-04"},"strain_display":{"value":"Canada/OP279037/2022-07-04"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OR759177","node_attrs":{"div":72,"accession":"OR759177","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.4"},"strain":{"value":"hMpxV/Canada/ON-PHOL089/2022"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759177/2022-09-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","G62952A","G100442A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G178818A","C181598T","-196615A"]}}},{"name":"OR759161","node_attrs":{"div":68,"accession":"OR759161","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.4"},"strain":{"value":"hMpxV/Canada/ON-PHOL073/2022"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759161/2022-08-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}}]}]},{"name":"NODE_0000107","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["G36259A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G174543A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}},"children":[{"name":"OP626135","node_attrs":{"div":67,"accession":"OP626135","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPXV/Germany/2022/RKI496"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP626135/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C40251T","C154472T","G167517A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"],"OPG058":["D62N"],"OPG181":["H21Y"],"OPG193":["E62K"]},"labels":{"aa":"OPG058: D62N; OPG181: H21Y; OPG193: E62K"}}},{"name":"OP863227","node_attrs":{"div":64,"accession":"OP863227","author":{"author":"Haw,M.,Probert,W.,Espinosa,A.,Kath,C.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Haw,M.,Probert,W.,Espinosa,A.,Kath,C.,O'Neil,R.,Bell,J.,Hacker,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDPH, VRDL"},"lineage":{"value":"B.1.4"},"strain":{"value":"hMpxV/USA/CA-CDPH-000052/2022"},"date":{"value":"2022-07-21"},"strain_display":{"value":"USA/OP863227/2022-07-21"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OQ547876","node_attrs":{"div":64,"accession":"OQ547876","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDPH, VRDL"},"lineage":{"value":"B.1.4"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000164/2022"},"date":{"value":"2022-06-28"},"strain_display":{"value":"USA/OQ547876/2022-06-28"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C699-","T700-","T701-","T6976-","C196727-","T196728-","T196729-"]}}},{"name":"NODE_0000108","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["-607T","C177720T","-196615A"],"OPG205":["R689C"]},"labels":{"aa":"OPG205: R689C"}},"children":[{"name":"OQ547900","node_attrs":{"div":66,"accession":"OQ547900","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDPH, VRDL"},"lineage":{"value":"B.1.4"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000185/2022"},"date":{"value":"2022-12-21"},"strain_display":{"value":"USA/OQ547900/2022-12-21"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T6976-","G92733A"],"OPG113":["E335K"]},"labels":{"aa":"OPG113: E335K"}}},{"name":"OQ503748","node_attrs":{"div":67,"accession":"OQ503748","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.4"},"strain":{"value":"MpxV/human/USA/WA-UW-108160/2022"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ503748/2022-10-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A80755C","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G159203A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG104":["C89G"],"OPG185":["G96E"]},"labels":{"aa":"OPG104: C89G; OPG185: G96E"}}}]},{"name":"NODE_0000109","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.4"}},"branch_attrs":{"mutations":{"nuc":["C25967T"],"OPG042":["W377*"]},"labels":{"aa":"OPG042: W377*"}},"children":[{"name":"OQ503808","node_attrs":{"div":73,"accession":"OQ503808","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00434/2022"},"date":{"value":"2022-09-28"},"strain_display":{"value":"USA/OQ503808/2022-09-28"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G70435A","C125412T","C141442T","C141511T","G158709A","A163469T","G175698A","G176439A","A196814-","A196815-","A196816-"],"OPG145":["S489L"],"OPG161":["S114L","S137F"],"OPG189":["E46V"],"OPG205":["D15N","D262N"]},"labels":{"aa":"OPG145: S489L; OPG161: S114L, S137F; OPG189: E46V; OPG205: D15N, D262N"}}},{"name":"OQ644775","node_attrs":{"div":69,"accession":"OQ644775","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.4"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00469/2022"},"date":{"value":"2022-11-18"},"strain_display":{"value":"USA/OQ644775/2022-11-18"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C97805T","C100640T","C105632T","C172792T","T196673-","G196674-"],"OPG117":["P586L"],"OPG124":["E113K"]},"labels":{"aa":"OPG117: P586L; OPG124: E113K"}}}]}]}]},{"name":"NODE_0000110","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["G5595A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C191615T"],"OPG015":["Q188*"],"OPG015_dup":["Q188*"]},"labels":{"aa":"OPG015: Q188*; OPG015_dup: Q188*","clade":"B.1.8"}},"children":[{"name":"OP215224","node_attrs":{"div":62,"accession":"OP215224","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/RKI235"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP215224/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP722502","node_attrs":{"div":64,"accession":"OP722502","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00243/2022"},"date":{"value":"2022-07-20"},"strain_display":{"value":"USA/OP722502/2022-07-20"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T731-","G732-","C733-","G53326A","G67898A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG085":["P212S"]},"labels":{"aa":"OPG085: P212S"}}},{"name":"NODE_0000111","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["G78034A","C80111T"],"OPG099":["D124N"]},"labels":{"aa":"OPG099: D124N"}},"children":[{"name":"ON622718","node_attrs":{"div":65,"accession":"ON622718","author":{"author":"Martinez-Puchol,S.,Coello,A.,Bordoy,A.E.,Soler,L.,Panisello,D.,Gonzalez-Gomez,S.,Clara,G.,Paris de Leon,A.,Not,A.,Hernandez,A.,Bofill-Mas,S.,Saludes,V.,Blanco,I.,Martro,E.,Cardona,P.-J.","value":"Martinez-Puchol,S.,Coello,A.,Bordoy,A.E.,Soler,L.,Panisello,D.,Gonzalez-Gomez,S.,Clara,G.,Paris de Leon,A.,Not,A.,Hernandez,A.,Bofill-Mas,S.,Saludes,V.,Blanco,I.,Martro,E.,Cardona,P.-J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Spain"},"clade_membership":{"value":"IIb"},"institution":{"value":"Microbiology, Hospital Universitari Germans Trias i Pujol, Spain"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/ES0001/HUGTiP/2022"},"date":{"value":"2022-05-20"},"strain_display":{"value":"Spain/ON622718/2022-05-20"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C14113-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T139150C","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","-196615A","-196616A"],"OPG156":["Q87R"]},"labels":{"aa":"OPG156: Q87R"}}},{"name":"NODE_0000112","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["G22643A","G63811A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"],"OPG038":["H173Y"]},"labels":{"aa":"OPG038: H173Y"}},"children":[{"name":"OP303781","node_attrs":{"div":66,"accession":"OP303781","author":{"author":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV_USA_2022_FL0018"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP303781/2022-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP415254","node_attrs":{"div":68,"accession":"OP415254","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPX_imBNaw_9000300"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415254/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T119985C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G189258A"]}}},{"name":"OP480416","node_attrs":{"div":72,"accession":"OP480416","author":{"author":"Deanhardt,B.,Miller,M.,Wang,J.R.","value":"Deanhardt,B.,Miller,M.,Wang,J.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of North Carolina at Chapel Hill, Department of Genetics"},"lineage":{"value":"B.1.8"},"strain":{"value":"hMPXV/USA/NC-UNC-0017/2022"},"date":{"value":"2022-08-24"},"strain_display":{"value":"USA/OP480416/2022-08-24"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G2079A","C12359T","A31053G","C89240T","G150404A","C173533A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C195131T"],"OPG002":["R225C"],"OPG002_dup":["R225C"],"OPG023":["R181Q"],"OPG047":["C48R"],"OPG109":["D70N"],"OPG176":["R199K"]},"labels":{"aa":"OPG002: R225C; OPG002_dup: R225C; OPG023: R181Q; OPG047: C48R; OPG109: D70N; OPG176: R199K"}}},{"name":"OP459214","node_attrs":{"div":66,"accession":"OP459214","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"lineage":{"value":"B.1.8"},"strain":{"value":"ANT-LDSP-ANT-MPX-23631-L"},"date":{"value":"2022-08-30"},"strain_display":{"value":"Colombia/OP459214/2022-08-30"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP642374","node_attrs":{"div":67,"accession":"OP642374","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.8"},"strain":{"value":"ANT-LDSP-ANT-MPX-24722-L"},"date":{"value":"2022-09-08"},"strain_display":{"value":"Colombia/OP642374/2022-09-08"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G168759A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG195":["R177K"]},"labels":{"aa":"OPG195: R177K"}}},{"name":"OQ320513","node_attrs":{"div":70,"accession":"OQ320513","author":{"author":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y.","value":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV_USA_2022_FL0009"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ320513/2022-10-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G4038A","A39081T","C67289T","G73790A","T133102-","A173284-","T173285-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C193172T"],"OPG057":["I372N"],"OPG085":["E415K"],"OPG094":["G4E"]},"labels":{"aa":"OPG057: I372N; OPG085: E415K; OPG094: G4E"}}},{"name":"OQ721938","node_attrs":{"div":68,"accession":"OQ721938","author":{"author":"Gigante,C.,Epie,N.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Perez,T.,Li,Y.","value":"Gigante,C.,Epie,N.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Perez,T.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV_USA_2022_SC0010"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721938/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C96649T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","G188382A"],"OPG117":["H201Y"]},"labels":{"aa":"OPG117: H201Y"}}},{"name":"OR759149","node_attrs":{"div":70,"accession":"OR759149","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.8"},"strain":{"value":"hMpxV/Canada/ON-PHOL055/2022"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759149/2022-08-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C8555T","G95862A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168089T","G181674A","-196615A"],"OPG116":["A168T"],"OPG210":["E107K"]},"labels":{"aa":"OPG116: A168T; OPG210: E107K"}}}]}]},{"name":"NODE_0000113","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","A150591-","T150592-","A150595-","T150596-","A150597-","T150598-","A150600-","T150601-","G161296A","-179172C","-179181C","C196308T"],"OPG001_dup":["S225L"]},"labels":{"aa":"OPG001_dup: S225L"}},"children":[{"name":"OP331337","node_attrs":{"div":63,"accession":"OP331337","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV_UK_2022_9000183"},"date":{"value":"2022-06-29"},"strain_display":{"value":"United Kingdom/OP331337/2022-06-29"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G902A","G150590-","G150593-","G150594-","G150599-","G150602-","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG001":["S225L"]},"labels":{"aa":"OPG001: S225L"}}},{"name":"OP615338","node_attrs":{"div":66,"accession":"OP615338","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/ON/RKI459"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP615338/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G89716A","G128858A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","C186220T"],"OPG110":["E29K"],"OPG210":["A1622V"]},"labels":{"aa":"OPG110: E29K; OPG210: A1622V"}}},{"name":"OP626130","node_attrs":{"div":64,"accession":"OP626130","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/RKI492"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OP626130/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C24929T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C179172-","C179181-","T196308C"],"OPG001_dup":["L225S"],"OPG040":["D184N"]},"labels":{"aa":"OPG001_dup: L225S; OPG040: D184N"}}},{"name":"OP555609","node_attrs":{"div":65,"accession":"OP555609","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.8"},"strain":{"value":"Monkeypox/PT0538/2022"},"date":{"value":"2022-08-23"},"strain_display":{"value":"Portugal/OP555609/2022-08-23"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","G902A","C25269T","G25692A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C179172-","C179181-"],"OPG001":["S225L"]},"labels":{"aa":"OPG001: S225L"}}},{"name":"OP894040","node_attrs":{"div":68,"accession":"OP894040","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/ON/RKI620"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP894040/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G2039A","G34298T","C37048T","G70190A","G150590-","G150593-","G150594-","G150599-","G150602-","G153094A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"],"OPG002":["S238L"],"OPG089":["E109K"],"OPG180":["D135N"]},"labels":{"aa":"OPG002: S238L; OPG089: E109K; OPG180: D135N"}}},{"name":"OR030928","node_attrs":{"div":64,"accession":"OR030928","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/UZ_REGA_17"},"date":{"value":"2022-07-19"},"strain_display":{"value":"Belgium/OR030928/2022-07-19"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G902A","C68981T","G150590-","G150593-","G150594-","G150599-","G150602-","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG001":["S225L"],"OPG087":["S42L"]},"labels":{"aa":"OPG001: S225L; OPG087: S42L"}}},{"name":"OR449682","node_attrs":{"div":63,"accession":"OR449682","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/Germany/2022/ON/RKI968"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449682/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"NODE_0000114","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.8"}},"branch_attrs":{"mutations":{"nuc":["C80545T","G102614A","G150590-","G150593-","G150594-","G150599-","G150602-","C170573T","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG103":["S182L"],"OPG122":["V63I"],"OPG198":["S179L"]},"labels":{"aa":"OPG103: S182L; OPG122: V63I; OPG198: S179L"}},"children":[{"name":"OR035714","node_attrs":{"div":66,"accession":"OR035714","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/UZ_REGA_108"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035714/2022-10-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OR095062","node_attrs":{"div":67,"accession":"OR095062","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.8"},"strain":{"value":"MPXV/UZ_REGA_244/Belgium/2022"},"date":{"value":"2022-08-16"},"strain_display":{"value":"Belgium/OR095062/2022-08-16"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C62305T"]}}}]}]}]},{"name":"NODE_0000121","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["C89906T","G94798A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG110":["S92F"],"OPG115":["E47K"]},"labels":{"aa":"OPG110: S92F; OPG115: E47K","clade":"B.1.10"}},"children":[{"name":"ON720848","node_attrs":{"div":64,"accession":"ON720848","author":{"author":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Spain"},"clade_membership":{"value":"IIb"},"institution":{"value":"Microbial Genomics, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"},"lineage":{"value":"B.1.10"},"strain":{"value":"MpxV/Spain/MD-HGUGM-6513479/2022"},"date":{"value":"2022-05-27"},"strain_display":{"value":"Spain/ON720848/2022-05-27"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A327-","T605-","T606-","A1697-","T4296-","T6587-","T6588-","T7253-","G7724-","T8017-","A8036-","T8499-","T9514-","A9869-","T10502-","A10914-","T11188-","C11749-","T11761-","T12121-","A15754-","A17087-","T18866-","A19360-","T20663-","A21081-","T21975-","T24678-","T25853-","T26099-","C27002-","A27114-","C27799-","A28529-","A28530-","T32194-","T33414-","G35949-","T37982-","T39131-","T39866-","T41744-","T42990-","C43014-","G43200-","A43443-","T44120-","T44738-","G46762-","T48675-","A49134-","G49833-","A51022-","A52765-","A54968-","A55124-","T55560-","T56040-","T57075-","A57277-","A58650-","T61749-","A62041-","T63628-","A64728-","A64935-","A65535-","A65967-","T66783-","A66843-","A67164-","C68466-","T68481-","C68899-","G69145-","A69744-","T69768-","A71254-","G71359-","T75833-","A76072-","T76084-","T76085-","A76153-","A76154-","A76890-","A77260-","T77803-","T78062-","A79042-","A79181-","G79217-","C79533T","A79787-","G80950-","C82482-","T84846-","T88095-","T88836-","T88941-","A89106-","T90646-","T91129-","T91370-","A91583-","A91705-","T94795-","A95341-","A95574-","G95742-","G95818-","A97351-","A97480-","A97501-","A97699-","A98683-","T101452-","G101515-","T102437-","T103367-","T103368-","T104279-","T105360-","T106596-","T108598-","A113921-","T113951-","C114431-","T114518-","T114755-","T115127-","G115801-","A116014-","C116494-","T116963-","T121121-","T121122-","G121269-","C121546-","T124022-","T124751-","A125249-","A126568-","T126682-","A126715-","A127250-","A127754-","A132023-","A132024-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133639-","T136780-","T137886-","A143045-","G143363-","T143478-","A144230-","T146131-","A148000-","A149727-","A150340-","T150538-","T150539-","A150635-","T150864-","A151490-","A151508-","G151545-","A152676-","T152686-","A153358-","A153424-","A153517-","T154862-","T155424-","C156607-","C156608-","A157997-","T163498-","T163597-","A163957-","A165461-","A166740-","G167640-","A167967-","T168120-","A170728-","T170758-","T170903-","T170904-","T172087-","T172667-","G179036-","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A179551-","A179950-","T180905-","G181052-","A181253-","C183534-","A183780-","T187080-","A190935-","A191015-","G191519-","A196613-","A196614-","T196888-","T197183-"],"OPG015_dup":["G156-"],"OPG016":["T176-"],"OPG019":["G49-"],"OPG021":["N95-"],"OPG023":["G385-"],"OPG043":["G53-"],"OPG044":["K147-"],"OPG066":["P223-"],"OPG068":["L159-","D545-"],"OPG070":["N145-"],"OPG074":["K523-"],"OPG084":["K3-","K272-","R416-"],"OPG085":["F457-"],"OPG087":["L15-","G97-"],"OPG090":["K26-"],"OPG096":["L83-"],"OPG098":["S121-"],"OPG099":["F47-"],"OPG100":["F19-"],"OPG102":["K33-"],"OPG104":["P24-"],"OPG109":["K206-"],"OPG111":["F128-"],"OPG112":["S42-"],"OPG115":["S46-"],"OPG116":["K72-"],"OPG117":["K435-","N478-","R551-"],"OPG118":["I80-"],"OPG122":["Y4-"],"OPG123":["K569-"],"OPG133":["K394-"],"OPG134":["E18-","P249-"],"OPG139":["P34-"],"OPG145":["F26-","F269-","K435-"],"OPG148":["I195-","F233-"],"OPG149":["K19-"],"OPG151":["K1034-"],"OPG164":["R90-"],"OPG165":["M239-"],"OPG172":["I192-"],"OPG175":["N96-"],"OPG176":["K178-"],"OPG178":["D13-"],"OPG180":["K223-","K276-"],"OPG181":["F151-"],"OPG189":["L56-","K209-"],"OPG190":["N114-"],"OPG192":["K4-"],"OPG193":["G103-","F263-"],"OPG198":["K231-"],"OPG208":["I96-"],"OPG209":["L130-"],"OPG210":["P727-"]},"labels":{"aa":"OPG015_dup: G156-; OPG016: T176-; OPG019: G49-; OPG021: N95-; OPG023: G385-; OPG043: G53-; OPG044: K147-; OPG066: P223-; OPG068: L159-, D545-; OPG070: N145-; OPG074: K523-; OPG084: K3-, K272-, R416-; OPG085: F457-; OPG087: L15-, G97-; OPG090: K26-; OPG096: L83-; OPG098: S121-; OPG099: F47-; OPG100: F19-; OPG102: K33-; OPG104: P24-; OPG109: K206-; OPG111: F128-; OPG112: S42-; OPG115: S46-; OPG116: K72-; OPG117: K435-, N478-, R551-; OPG118: I80-; OPG122: Y4-; OPG123: K569-; OPG133: K394-; OPG134: E18-, P249-; OPG139: P34-; OPG145: F26-, F269-, K435-; OPG148: I195-, F233-; OPG149: K19-; OPG151: K1034-; OPG164: R90-; OPG165: M239-; OPG172: I192-; OPG175: N96-; OPG176: K178-; OPG178: D13-; OPG180: K223-, K276-; OPG181: F151-; OPG189: L56-, K209-; OPG190: N114-; OPG192: K4-; OPG193: G103-, F263-; OPG198: K231-; OPG208: I96-; OPG209: L130-; OPG210: P727-"}}},{"name":"OP245334","node_attrs":{"div":65,"accession":"OP245334","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPX/PT0081/2022"},"date":{"value":"2022-07-23"},"strain_display":{"value":"Portugal/OP245334/2022-07-23"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-609T","G610-","T611-","C120237T","G126047A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","A196619-","T196620-"],"OPG148":["R21K"]},"labels":{"aa":"OPG148: R21K"}}},{"name":"OP205110","node_attrs":{"div":63,"accession":"OP205110","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV_UK_2022_9000147"},"date":{"value":"2022-06-14"},"strain_display":{"value":"United Kingdom/OP205110/2022-06-14"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP205091","node_attrs":{"div":63,"accession":"OP205091","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV_UK_2022_9000103"},"date":{"value":"2022-06-13"},"strain_display":{"value":"United Kingdom/OP205091/2022-06-13"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP450985","node_attrs":{"div":63,"accession":"OP450985","author":{"author":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y.","value":"Gigante,C.M.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.L.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV_USA_2022_TX0019"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP450985/2022-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","A136552-","T136553-","C136554-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP484683","node_attrs":{"div":65,"accession":"OP484683","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Germany/2022/RKI362"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP484683/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C17027T","C84943T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-"],"OPG029":["D15N"],"OPG105":["S1273F"]},"labels":{"aa":"OPG029: D15N; OPG105: S1273F"}}},{"name":"OP894038","node_attrs":{"div":64,"accession":"OP894038","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Germany/2022/ON/RKI618"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP894038/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C33964T","T136514-","C136515-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","G181052-"],"OPG052":["R11Q"],"OPG153":["D385-"],"OPG209":["G179-"]},"labels":{"aa":"OPG052: R11Q; OPG153: D385-; OPG209: G179-"}}},{"name":"OQ773504","node_attrs":{"div":65,"accession":"OQ773504","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Germany/2022/ON/RKI885"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773504/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C33103T","A41660-","A41661-","T41662-","T41663-","T41664-","G41665-","T41666-","T41667-","T41668-","T41669-","A41670-","C41671-","T41672-","C41673-","T41674-","A41675-","T41676-","A41677-","C45605T","G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG049":["E17K"],"OPG061":["Y70-","R71-","V72-","K73-","Q74-","I75-"]},"labels":{"aa":"OPG049: E17K; OPG061: Y70-, R71-, V72-, K73-, Q74-, I75-"}}},{"name":"OQ581847","node_attrs":{"div":76,"accession":"OQ581847","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Spain"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0005b/2022"},"date":{"value":"2022-07-01"},"strain_display":{"value":"Spain/OQ581847/2022-07-01"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A43453G","A66769C","T88735A","G90070A","C101656T","G104325A","C121681T","G127869A","G132490A","T133095A","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T139779C","G140866T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C151204T","T176743A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG063":["L79P"],"OPG085":["V588G"],"OPG109":["E238V"],"OPG110":["D147N"],"OPG123":["A249V"],"OPG150":["G31R"],"OPG160":["S70Y"],"OPG205":["L363*"]},"labels":{"aa":"OPG063: L79P; OPG085: V588G; OPG109: E238V; OPG110: D147N; OPG123: A249V; OPG150: G31R; OPG160: S70Y; OPG205: L363*"}}},{"name":"OR264420","node_attrs":{"div":64,"accession":"OR264420","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.10"},"strain":{"value":"45_B"},"date":{"value":"2022-07-10"},"strain_display":{"value":"Australia/OR264420/2022-07-10"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G63147A","-179218A","-179219T","-179220T"]}}},{"name":"NODE_0000122","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C150831T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-"]}},"children":[{"name":"ON959143","node_attrs":{"div":65,"accession":"ON959143","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Finland"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPX-96/Finland/2022"},"date":{"value":"2022-06-16"},"strain_display":{"value":"Finland/ON959143/2022-06-16"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188491T"]}}},{"name":"OP382489","node_attrs":{"div":65,"accession":"OP382489","author":{"author":"Colson,P.","value":"Colson,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"lineage":{"value":"B.1.10"},"strain":{"value":"hMPXV-IHU00012"},"date":{"value":"2022-07-19"},"strain_display":{"value":"France/OP382489/2022-07-19"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G109437A","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G150603-","A150604-","T150605-","A150606-","T150607-","G150608-","A150609-","T150610-","G150611-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG129":["S523L"],"OPG153":["D384-","D385-"]},"labels":{"aa":"OPG129: S523L; OPG153: D384-, D385-"}}},{"name":"OP879740","node_attrs":{"div":64,"accession":"OP879740","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"lineage":{"value":"B.1.10"},"strain":{"value":"NJ-MPXV-022"},"date":{"value":"2022-07-06"},"strain_display":{"value":"USA/OP879740/2022-07-06"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-"]}}}]},{"name":"NODE_0000123","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["C20879T","C60094T"],"OPG036":["M62I"],"OPG080":["R642K"]},"labels":{"aa":"OPG036: M62I; OPG080: R642K"}},"children":[{"name":"OP415264","node_attrs":{"div":66,"accession":"OP415264","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPX_Tga3e9_9000325"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415264/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G86904A","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035722","node_attrs":{"div":66,"accession":"OR035722","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/UZ_REGA_116"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035722/2022-10-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G149818A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG176":["D4N"]},"labels":{"aa":"OPG176: D4N"}}},{"name":"OR464201","node_attrs":{"div":65,"accession":"OR464201","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV_USA_2022_NY0053"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OR464201/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-"]}}}]},{"name":"NODE_0000124","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["G50672A","C179265-","A179266-","T179267-"],"OPG070":["R28K"]},"labels":{"aa":"OPG070: R28K"}},"children":[{"name":"OP642387","node_attrs":{"div":64,"accession":"OP642387","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.10"},"strain":{"value":"ANT-LDSP-ANT-MPX-24914-L"},"date":{"value":"2022-09-09"},"strain_display":{"value":"Colombia/OP642387/2022-09-09"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP689664","node_attrs":{"div":66,"accession":"OP689664","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.10"},"strain":{"value":"MPXV/Germany/2022/ON/RKI511"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"Germany/OP689664/2022-10-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C13624T","C43472T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG063":["E73K"]},"labels":{"aa":"OPG063: E73K"}}},{"name":"OQ696103","node_attrs":{"div":69,"accession":"OQ696103","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"lineage":{"value":"B.1.10"},"strain":{"value":"ANT-LDSP-ANT-MPX-31501C"},"date":{"value":"2022-11-22"},"strain_display":{"value":"Colombia/OQ696103/2022-11-22"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G32863A","G45416A","C72770T","C123118T","C148771T","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG092":["E60K"],"OPG174":["D209N"]},"labels":{"aa":"OPG092: E60K; OPG174: D209N"}}},{"name":"NODE_0000125","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.10"}},"branch_attrs":{"mutations":{"nuc":["C49265T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-179265C","-179266A","-179267T"]}},"children":[{"name":"OP536764","node_attrs":{"div":66,"accession":"OP536764","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.10"},"strain":{"value":"9000385"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536764/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","C100007T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"],"OPG118":["S521F"]},"labels":{"aa":"OPG118: S521F"}}},{"name":"OP459218","node_attrs":{"div":65,"accession":"OP459218","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"lineage":{"value":"B.1.10"},"strain":{"value":"ANT-LDSP-ANT-MPX-23655-L"},"date":{"value":"2022-08-30"},"strain_display":{"value":"Colombia/OP459218/2022-08-30"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP819958","node_attrs":{"div":65,"accession":"OP819958","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.10"},"strain":{"value":"QUI_INS_MPX_0967_L"},"date":{"value":"2022-10-15"},"strain_display":{"value":"Colombia/OP819958/2022-10-15"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150603-","A150604-","T150605-","A150606-","T150607-","G150608-","A150609-","T150610-","G150611-"]}}}]}]}]},{"name":"OQ773485_NODE_0000126_merged","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["C182950T"],"OPG210":["S532L"]},"labels":{"aa":"OPG210: S532L","clade":"B.1.12"}},"children":[{"name":"OQ773485","node_attrs":{"div":62,"accession":"OQ773485","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV/Germany/2022/ON/RKI866"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773485/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G1302A","G150551-","A150563-","T150564-","G150565-","A150566-","T150567-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179189A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"],"OPG001":["L92F"]},"labels":{"aa":"OPG001: L92F"}}},{"name":"OP539926","node_attrs":{"div":67,"accession":"OP539926","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00141/2022"},"date":{"value":"2022-08-25"},"strain_display":{"value":"USA/OP539926/2022-08-25"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C23759T","G55059A","C84767T","G102972A","G144497A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A190409-","A190410-","T190411-","G190412-","G190413-","A190414-","T190415-","T190416-","C190417-","G190418-","C190419-","G190420-","T190421-","A190422-","T190423-","A190424-","G190425-","C190426-","T190427-","A190428-","T190429-","T190430-","T190431-","A190432-","C190433-","G190434-","T190435-","A190436-","T190437-","T190438-","A190439-","G190440-","T190441-","A190442-","T190443-","C190444-","G190445-","G190446-","C190447-","A190448-","T190449-","C190450-","T190451-","C190452-","T190453-","T190454-","T190455-","T190456-","G190457-","T190458-","A190459-","T190460-","C190461-","T190462-","T190463-","G190464-","T190465-","T190466-","A190467-","A190468-","T190469-","T190470-","G190471-","T190472-","C190473-","A190474-","C190475-","A190476-","A190477-","A190478-","C190479-","T190480-","A190481-","G190482-","T190483-","A190484-","C190485-","A190486-","T190487-","T190488-","A190489-","C190490-","T190491-","T190492-","C190493-","A190494-","A190495-","T190496-","C190497-","T190498-","G190499-","A190500-","A190501-","A190502-","A190503-","T190504-","A190505-"],"OPG073":["S28L"],"OPG122":["R182Q"],"OPG166":["E34K"]},"labels":{"aa":"OPG073: S28L; OPG122: R182Q; OPG166: E34K"}}},{"name":"OP605580","node_attrs":{"div":63,"accession":"OP605580","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"lineage":{"value":"B.1.12"},"strain":{"value":"Slovenia-MPXV-39-2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Slovenia/OP605580/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","C179082T","C179091T","T179094A","C179100T","T179103A","C179109T","T179112A","C179118T","T179121A","C179127T","T179130A","C179136T","C179145T","T179148A","C179154T","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179239A","-179240T","-179241A","-179242T","-179243A","G189288A"]}}},{"name":"OP605566","node_attrs":{"div":63,"accession":"OP605566","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"lineage":{"value":"B.1.12"},"strain":{"value":"Slovenia-MPXV-24-2022"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Slovenia/OP605566/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","C167944T","G196973-","A196974-","A196975-"],"OPG193":["S204L"]},"labels":{"aa":"OPG193: S204L"}}},{"name":"NODE_0000127","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G1302A","G78328A","C195908T"],"OPG001":["L92F"],"OPG001_dup":["L92F"]},"labels":{"aa":"OPG001: L92F; OPG001_dup: L92F"}},"children":[{"name":"OP524001","node_attrs":{"div":63,"accession":"OP524001","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV/Germany/2022/RKI399"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP524001/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000128","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["C57550T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP415206","node_attrs":{"div":64,"accession":"OP415206","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPX_BhVKjm_9000232"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415206/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP415207","node_attrs":{"div":64,"accession":"OP415207","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPX_BhVKjm_9000233"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415207/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000129","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G111084A"]}},"children":[{"name":"OP013003","node_attrs":{"div":63,"accession":"OP013003","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.12"},"strain":{"value":"MpxV/human/CAN/UN-NML-3276/2022"},"date":{"value":"2022-05-31"},"strain_display":{"value":"Canada/OP013003/2022-05-31"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"ON880548","node_attrs":{"div":63,"accession":"ON880548","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.12"},"strain":{"value":"MpxV/human/CAN/UN-NML-3448/2022"},"date":{"value":"2022-06-03"},"strain_display":{"value":"Canada/ON880548/2022-06-03"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000130","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G121510A"]}},"children":[{"name":"ON880540","node_attrs":{"div":64,"accession":"ON880540","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.12"},"strain":{"value":"MpxV/human/CAN/UN-NML-3342/2022"},"date":{"value":"2022-06-01"},"strain_display":{"value":"Canada/ON880540/2022-06-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OR759170","node_attrs":{"div":69,"accession":"OR759170","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.12"},"strain":{"value":"hMpxV/Canada/ON-PHOL082/2022"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759170/2022-08-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","G10060A","G37022A","C132410T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G154793A","C180055T","-196615A"],"OPG055":["S21F"],"OPG181":["D128N"]},"labels":{"aa":"OPG055: S21F; OPG181: D128N"}}}]},{"name":"NODE_0000131","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G98233A","G98455A","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG117":["D729N"],"OPG118":["G4K"]},"labels":{"aa":"OPG117: D729N; OPG118: G4K"}},"children":[{"name":"ON880413","node_attrs":{"div":66,"accession":"ON880413","author":{"author":"Coletti,T.M.,Ghilardi,F.,khan,M.J.,Claro,I.M.,Valenca,I.N.,Faria,N.R.,Sabino,E.C.","value":"Coletti,T.M.,Ghilardi,F.,khan,M.J.,Claro,I.M.,Valenca,I.N.,Faria,N.R.,Sabino,E.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Brazil"},"clade_membership":{"value":"IIb"},"institution":{"value":"Imperial College London, School of Public Health"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPX/BR0002/2022"},"date":{"value":"2022-06-14"},"strain_display":{"value":"Brazil/ON880413/2022-06-14"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C76334T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG097":["R181K"]},"labels":{"aa":"OPG097: R181K"}}},{"name":"NODE_0000132","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G98456A","-179172C","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C"]}},"children":[{"name":"OP171920","node_attrs":{"div":68,"accession":"OP171920","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV22/human/USA-NE-31"},"date":{"value":"2022-07-04"},"strain_display":{"value":"USA/OP171920/2022-07-04"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G102694A","G160484A","-179173A","-179174T","-179175T","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"OP303780","node_attrs":{"div":66,"accession":"OP303780","author":{"author":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV_USA_2022_FL0017"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP303780/2022-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"]}}},{"name":"OP270022","node_attrs":{"div":69,"accession":"OP270022","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.12"},"strain":{"value":"MpxV/human/CAN/UN-NML-3972/2022"},"date":{"value":"2022-07-04"},"strain_display":{"value":"Canada/OP270022/2022-07-04"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","G3361A","C152970T","-179173A","-179174T","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G181349A","C193849T"],"OPG003":["S416L"],"OPG003_dup":["S416L"]},"labels":{"aa":"OPG003: S416L; OPG003_dup: S416L"}}},{"name":"OQ626770","node_attrs":{"div":69,"accession":"OQ626770","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV22/human/USA-NE-324"},"date":{"value":"2022-09-29"},"strain_display":{"value":"USA/OQ626770/2022-09-29"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C3438T","C10484T","A61974G","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G193772A","-196615A","-196616A","-196617A"]}}},{"name":"OR209309","node_attrs":{"div":69,"accession":"OR209309","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV_USA_2022_TN0019"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR209309/2022-12-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C93601T","C94418T","T133101-","T133102-","C136029T","-179173A","-179174T","-179175T","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["A624V"],"OPG114":["E84K"]},"labels":{"aa":"OPG113: A624V; OPG114: E84K"}}},{"name":"NODE_0000133","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G153910A","C179199-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"],"OPG180":["E407K"]},"labels":{"aa":"OPG180: E407K"}},"children":[{"name":"OQ427114","node_attrs":{"div":68,"accession":"OQ427114","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV_USA_2022_NY0039"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ427114/2022-10-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G71407A","-179173A","-179174T","-179175T","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-196615A"],"OPG091":["R13K"]},"labels":{"aa":"OPG091: R13K"}}},{"name":"OQ918701","node_attrs":{"div":72,"accession":"OQ918701","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00490/2023"},"date":{"value":"2023-02-10"},"strain_display":{"value":"USA/OQ918701/2023-02-10"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C21910T","G28483A","G39552A","A57421-","C57422-","A57423-","A57424-","A57425-","A57426-","A57427-","G57428-","G57429-","A57430-","C57431-","A57432-","T57433-","G57434-","T57435-","A57436-","A57437-","A57438-","C57439-","T57440-","T57441-","G132490A","C150443T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG037":["R175K"],"OPG057":["S215F"],"OPG075":["K20-","F21-","T22-","C23-","P24-","F25-","C26-"],"OPG176":["T212I"]},"labels":{"aa":"OPG037: R175K; OPG057: S215F; OPG075: K20-, F21-, T22-, C23-, P24-, F25-, C26-; OPG176: T212I"}}},{"name":"OR759180","node_attrs":{"div":71,"accession":"OR759180","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.12"},"strain":{"value":"hMpxV/Canada/ON-PHOL092/2022"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759180/2022-09-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","C16209T","C24208T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","G182088A","G182189A","A196614-"],"OPG027":["E57K"],"OPG210":["E245K"]},"labels":{"aa":"OPG027: E57K; OPG210: E245K"}}},{"name":"OR464203","node_attrs":{"div":69,"accession":"OR464203","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV_USA_2022_NY0055"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OR464203/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T3777C","C119854T","-179173A","-179174T","-179175T","C179181-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","A193433G"],"OPG137":["H85Y"]},"labels":{"aa":"OPG137: H85Y"}}}]},{"name":"NODE_0000134","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["C24231T","-179173A","-179174T","-179175T","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T"]}},"children":[{"name":"OR095033","node_attrs":{"div":68,"accession":"OR095033","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPXV/UZ_REGA_215/Belgium/2022"},"date":{"value":"2022-08-08"},"strain_display":{"value":"Belgium/OR095033/2022-08-08"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G61102A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG080":["S306F"]},"labels":{"aa":"OPG080: S306F"}}},{"name":"NODE_0000135","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G23457A"],"OPG039":["S221F"]},"labels":{"aa":"OPG039: S221F"}},"children":[{"name":"OP415236","node_attrs":{"div":68,"accession":"OP415236","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.12"},"strain":{"value":"MPX_ilzdZn_9000269"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415236/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A190409-","A190410-","T190411-","G190412-","G190413-","A190414-","T190415-","T190416-","C190417-","G190418-","C190419-","G190420-","T190421-","A190422-","T190423-","A190424-","G190425-","C190426-"]}}},{"name":"OR264365","node_attrs":{"div":68,"accession":"OR264365","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.12"},"strain":{"value":"12_A"},"date":{"value":"2022-07-18"},"strain_display":{"value":"Australia/OR264365/2022-07-18"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000136","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.12"}},"branch_attrs":{"mutations":{"nuc":["G184227A"],"OPG210":["D958N"]},"labels":{"aa":"OPG210: D958N"}},"children":[{"name":"OP390179","node_attrs":{"div":68,"accession":"OP390179","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"lineage":{"value":"B.1.12"},"strain":{"value":"BOL-UNIMOL-MPX-293015-L"},"date":{"value":"2022-08-24"},"strain_display":{"value":"Colombia/OP390179/2022-08-24"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP382485","node_attrs":{"div":68,"accession":"OP382485","author":{"author":"Colson,P.","value":"Colson,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"lineage":{"value":"B.1.12"},"strain":{"value":"hMPXV-IHU00008"},"date":{"value":"2022-07-05"},"strain_display":{"value":"France/OP382485/2022-07-05"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]}]}]}]}]}]},{"name":"NODE_0000050_NODE_0000115_merged","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["C70780T","-150590G","-150593G","-150594G","-150599G","-150602G"]},"labels":{"clade":"B.1.5"}},"children":[{"name":"OP150925","node_attrs":{"div":62,"accession":"OP150925","author":{"author":"Gigante,C.,Xia,D.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y.","value":"Gigante,C.,Xia,D.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV_USA_2022_GA001"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/OP150925/2022-05-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON780017","node_attrs":{"div":62,"accession":"ON780017","author":{"author":"Gramigna,G.,Giombini,E.,Gruber,C.E.M.,Rueca,M.,Carletti,F.,Cicalini,S.,Lapa,D.,Puro,V.,Marani,A.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Rivano Capparuccia,M.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F.","value":"Gramigna,G.,Giombini,E.,Gruber,C.E.M.,Rueca,M.,Carletti,F.,Cicalini,S.,Lapa,D.,Puro,V.,Marani,A.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Rivano Capparuccia,M.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Italy"},"clade_membership":{"value":"IIb"},"institution":{"value":"INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology"},"lineage":{"value":"B.1.5"},"strain":{"value":"INMI-Pt4"},"date":{"value":"2022-05-21"},"strain_display":{"value":"Italy/ON780017/2022-05-21"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A"]}}},{"name":"OQ339211","node_attrs":{"div":63,"accession":"OQ339211","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/ON/RKI692"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OQ339211/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","G147459A","G150551-","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG044":["K147-"]},"labels":{"aa":"OPG044: K147-"}}},{"name":"ON959173","node_attrs":{"div":64,"accession":"ON959173","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/RKI159"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/ON959173/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G78593A","C126202T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"],"OPG148":["P73S"]},"labels":{"aa":"OPG148: P73S"}}},{"name":"ON918656","node_attrs":{"div":66,"accession":"ON918656","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Taiwan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/human/Taiwan/110-231642/2022"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Taiwan/ON918656/2022-06-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C28702T","T34793C","T50861C","C51777T","G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG054":["T402A"],"OPG070":["V91A"],"OPG071":["E888K"]},"labels":{"aa":"OPG054: T402A; OPG070: V91A; OPG071: E888K"}}},{"name":"ON843165","node_attrs":{"div":62,"accession":"ON843165","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.5"},"strain":{"value":"Monkeypox/PT0033/2022"},"date":{"value":"2022-05-24"},"strain_display":{"value":"Portugal/ON843165/2022-05-24"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}}},{"name":"OP245318","node_attrs":{"div":66,"accession":"OP245318","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPX/PT0064/2022"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Portugal/OP245318/2022-08-01"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G71227A","C133867T","C134247T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G158866A"],"OPG090":["E17K"]},"labels":{"aa":"OPG090: E17K"}}},{"name":"OP450990","node_attrs":{"div":65,"accession":"OP450990","author":{"author":"Gigante,C.M.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y.","value":"Gigante,C.M.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV_USA_2022_NV0001"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP450990/2022-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G75554A","G147179A","G150590-","G150593-","G150594-","G150599-","G150602-","G159373A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG185":["E153K"]},"labels":{"aa":"OPG185: E153K"}}},{"name":"OP414288","node_attrs":{"div":62,"accession":"OP414288","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.5"},"strain":{"value":"Monkeypox/PT0244/2022"},"date":{"value":"2022-06-21"},"strain_display":{"value":"Portugal/OP414288/2022-06-21"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","-196615A"]}}},{"name":"OP536756","node_attrs":{"div":64,"accession":"OP536756","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.5"},"strain":{"value":"9000376"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP536756/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C69888T","C150392T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG089":["S8L"],"OPG176":["S195F"]},"labels":{"aa":"OPG089: S8L; OPG176: S195F"}}},{"name":"OP783902","node_attrs":{"div":62,"accession":"OP783902","author":{"author":"Laubscher,F.,Marques-Melancia,S.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Marques-Melancia,S.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Switzerland"},"clade_membership":{"value":"IIb"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"lineage":{"value":"B.1.5"},"strain":{"value":"hMPXV-CH-38347314/2022"},"date":{"value":"2022-06-08"},"strain_display":{"value":"Switzerland/OP783902/2022-06-08"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ274884","node_attrs":{"div":62,"accession":"OQ274884","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/ON/RKI665"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ274884/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OR264397","node_attrs":{"div":66,"accession":"OR264397","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.5"},"strain":{"value":"34_A"},"date":{"value":"2022-08-16"},"strain_display":{"value":"Australia/OR264397/2022-08-16"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","C30283T","C37054T","G150590-","G150593-","G150594-","G150599-","G150602-","-179197T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","G179589A","G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N"}}},{"name":"ON959175","node_attrs":{"div":62,"accession":"ON959175","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/RKI162"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/ON959175/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}}},{"name":"OP524008","node_attrs":{"div":62,"accession":"OP524008","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/RKI406"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP524008/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}}},{"name":"NODE_0000051","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["C774-","G775-","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G159001A","A196659-","T196660-"],"OPG185":["D29N"]},"labels":{"aa":"OPG185: D29N"}},"children":[{"name":"OP245340","node_attrs":{"div":63,"accession":"OP245340","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPX/PT0090/2022"},"date":{"value":"2022-07-21"},"strain_display":{"value":"Portugal/OP245340/2022-07-21"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179175T","T179244-","C179245-","G179246-","T179247-"]}}},{"name":"OP555650","node_attrs":{"div":64,"accession":"OP555650","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.5"},"strain":{"value":"Monkeypox/PT0579/2022"},"date":{"value":"2022-09-10"},"strain_display":{"value":"Portugal/OP555650/2022-09-10"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C41022T","A136552-","T136553-","C136554-"],"OPG060":["R54K"],"OPG153":["D385-"]},"labels":{"aa":"OPG060: R54K; OPG153: D385-"}}}]},{"name":"NODE_0000117","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","C160426T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A"]}},"children":[{"name":"OQ503755","node_attrs":{"div":68,"accession":"OQ503755","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.5"},"strain":{"value":"MpxV/human/USA/WA-UW-113327/2022"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"USA/OQ503755/2022-11-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T10449-","A10450-","G10451-","A10452-","T10453-","G75332A","T124690C","C135762T","C144211T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G185394A"],"OPG095":["R177K"],"OPG210":["E1347K"]},"labels":{"aa":"OPG095: R177K; OPG210: E1347K"}}},{"name":"NODE_0000118","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["G111379A","G165326A"],"OPG130":["S175L"],"OPG190":["E69K"]},"labels":{"aa":"OPG130: S175L; OPG190: E69K"}},"children":[{"name":"OP650029","node_attrs":{"div":68,"accession":"OP650029","author":{"author":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T.","value":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV22/human/USA-OK-81"},"date":{"value":"2022-07-26"},"strain_display":{"value":"USA/OP650029/2022-07-26"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G22207A","C82187T","C120671T","T136555-","G136558C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG037":["S76F"]},"labels":{"aa":"OPG037: S76F"}}},{"name":"OQ320464","node_attrs":{"div":65,"accession":"OQ320464","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV_USA_2022_NY0025"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OQ320464/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OQ721933","node_attrs":{"div":66,"accession":"OQ721933","author":{"author":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y.","value":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV_USA_2022_OH0005"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ721933/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G48045A","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","G173318-","G173319-","G173320-","C173321-","A173322-","A173323-","A173324-","A173325-","C173326-","A173327-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"]}}}]}]},{"name":"NODE_0000119","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["C44333T","G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179235C"],"OPG064":["M522I"]},"labels":{"aa":"OPG064: M522I"}},"children":[{"name":"OP415189","node_attrs":{"div":63,"accession":"OP415189","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPX_luLfgA_9000208"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415189/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035702","node_attrs":{"div":67,"accession":"OR035702","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/UZ_REGA_96"},"date":{"value":"2022-05-30"},"strain_display":{"value":"Belgium/OR035702/2022-05-30"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C29315T","C60396T","G149807A","C161572T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG046":["D139N"]},"labels":{"aa":"OPG046: D139N"}}},{"name":"OR035675","node_attrs":{"div":64,"accession":"OR035675","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/UZ_REGA_69"},"date":{"value":"2022-06-30"},"strain_display":{"value":"Belgium/OR035675/2022-06-30"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G161488A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR449646","node_attrs":{"div":64,"accession":"OR449646","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.5"},"strain":{"value":"MPXV/Germany/2022/ON/RKI932"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449646/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G149300A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","C179235-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"NODE_0000120","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.5"}},"branch_attrs":{"mutations":{"nuc":["G93512T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C179235-"],"OPG113":["K594N"]},"labels":{"aa":"OPG113: K594N"}},"children":[{"name":"OP358276","node_attrs":{"div":67,"accession":"OP358276","author":{"author":"Tramuto,F.","value":"Tramuto,F."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Italy"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Palermo, Department of Health Promotion Sciences Maternal and Infant Care, Internal Medicine and Medical Specialties \"G. D'Alessandro\"\"\""},"lineage":{"value":"B.1.5"},"strain":{"value":"SIC-AOUP-UNIPA_VL_9aug"},"date":{"value":"2022-08-09"},"strain_display":{"value":"Italy/OP358276/2022-08-09"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C33103T","C114490T","C133295T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-"],"OPG049":["E17K"],"OPG133":["D403N"]},"labels":{"aa":"OPG049: E17K; OPG133: D403N"}}},{"name":"OR264417","node_attrs":{"div":65,"accession":"OR264417","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.5"},"strain":{"value":"43_A"},"date":{"value":"2022-06-22"},"strain_display":{"value":"Australia/OR264417/2022-06-22"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G2898A","C179226-","C194312T"]}}}]}]}]},{"name":"NODE_0000137","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N","clade":"B.1.2"}},"children":[{"name":"OP150927","node_attrs":{"div":62,"accession":"OP150927","author":{"author":"Gigante,C.,Pavlick,J.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y.","value":"Gigante,C.,Pavlick,J.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_USA_2022_WA001"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"USA/OP150927/2022-05-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON929079","node_attrs":{"div":62,"accession":"ON929079","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/RKI124"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/ON929079/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP484696","node_attrs":{"div":63,"accession":"OP484696","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/RKI344"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP484696/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G118391A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OQ274892","node_attrs":{"div":62,"accession":"OQ274892","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/ON/RKI673"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ274892/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-"]}}},{"name":"OQ773441","node_attrs":{"div":62,"accession":"OQ773441","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/ON/RKI822"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773441/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"NODE_0000138","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G5375A","C191835T"],"OPG015":["A261V"],"OPG015_dup":["A261V"]},"labels":{"aa":"OPG015: A261V; OPG015_dup: A261V"}},"children":[{"name":"OP378702","node_attrs":{"div":64,"accession":"OP378702","author":{"author":"Gigante,C.M.,Johnson,S.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Riner,D.,Li,Y.","value":"Gigante,C.M.,Johnson,S.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Riner,D.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_USA_2022_MI0001"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP378702/2022-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T4775-","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C184829T","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OR759146","node_attrs":{"div":65,"accession":"OR759146","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.2"},"strain":{"value":"hMpxV/Canada/ON-PHOL053/2022"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759146/2022-08-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C3405T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C170573T","G193805A"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}}}]},{"name":"NODE_0000139","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["C20992T","G143789A","C147168T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG036":["D25N"],"OPG165":["D92N"],"OPG171":["L61F"]},"labels":{"aa":"OPG036: D25N; OPG165: D92N; OPG171: L61F"}},"children":[{"name":"OP279039","node_attrs":{"div":65,"accession":"OP279039","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/CAN/UN-NML-4117/2022"},"date":{"value":"2022-06-28"},"strain_display":{"value":"Canada/OP279039/2022-06-28"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OP355567","node_attrs":{"div":66,"accession":"OP355567","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/ON/RKI307"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP355567/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G49821A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A188351-"],"OPG068":["E541K"]},"labels":{"aa":"OPG068: E541K"}}},{"name":"OR264414","node_attrs":{"div":65,"accession":"OR264414","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.2"},"strain":{"value":"42_C"},"date":{"value":"2022-06-22"},"strain_display":{"value":"Australia/OR264414/2022-06-22"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T"]}}}]},{"name":"NODE_0000140","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188391T"]}},"children":[{"name":"OP205083","node_attrs":{"div":63,"accession":"OP205083","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_UK_2022_9000092"},"date":{"value":"2022-05-25"},"strain_display":{"value":"United Kingdom/OP205083/2022-05-25"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP205086","node_attrs":{"div":63,"accession":"OP205086","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_UK_2022_9000097"},"date":{"value":"2022-06-06"},"strain_display":{"value":"United Kingdom/OP205086/2022-06-06"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP415205","node_attrs":{"div":72,"accession":"OP415205","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPX_TcUINH_9000230"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415205/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T11371C","G34303A","C85322T","G92048A","G123119A","G129583A","C140931T","C153104T","C178378T"],"OPG053":["P130S"],"OPG143":["S66L"],"OPG180":["S138F"]},"labels":{"aa":"OPG053: P130S; OPG143: S66L; OPG180: S138F"}}},{"name":"OP536784","node_attrs":{"div":63,"accession":"OP536784","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.2"},"strain":{"value":"9000408"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536784/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OP605583","node_attrs":{"div":68,"accession":"OP605583","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"lineage":{"value":"B.1.2"},"strain":{"value":"Slovenia-MPXV-42-2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Slovenia/OP605583/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A161-","-607T","C17614A","C27187T","G111484A","G147305A","C159401A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG030":["V74L"],"OPG043":["D257N"],"OPG130":["T140I"],"OPG185":["S162Y"]},"labels":{"aa":"OPG030: V74L; OPG043: D257N; OPG130: T140I; OPG185: S162Y"}}},{"name":"OP555625","node_attrs":{"div":65,"accession":"OP555625","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.2"},"strain":{"value":"Monkeypox/PT0554/2022"},"date":{"value":"2022-08-30"},"strain_display":{"value":"Portugal/OP555625/2022-08-30"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G29102A","G45781A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG045":["S54L"],"OPG064":["H40Y"]},"labels":{"aa":"OPG045: S54L; OPG064: H40Y"}}},{"name":"OP881946","node_attrs":{"div":67,"accession":"OP881946","author":{"author":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y.","value":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_USA_2022_FL0027"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OP881946/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G65961A","G126646A","C168226T","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C188998T"],"OPG084":["E414K"],"OPG148":["E221K"]},"labels":{"aa":"OPG084: E414K; OPG148: E221K"}}},{"name":"OQ626772","node_attrs":{"div":66,"accession":"OQ626772","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV22/human/USA-NE-341"},"date":{"value":"2022-10-11"},"strain_display":{"value":"USA/OQ626772/2022-10-11"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G10523A","A16620-","T16621-","C16622-","G92433A","C160426T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A","-196616A","-196617A"],"OPG029":["D154-"],"OPG113":["A235T"]},"labels":{"aa":"OPG029: D154-; OPG113: A235T"}}},{"name":"OR086973","node_attrs":{"div":64,"accession":"OR086973","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/UZ_REGA_164/Belgium/2022"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR086973/2022-07-27"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G135633A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"NODE_0000141","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G133968T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}},"children":[{"name":"OP881952","node_attrs":{"div":66,"accession":"OP881952","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_USA_2022_TX0030"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP881952/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G164971A","C188929T"],"OPG189":["E547K"]},"labels":{"aa":"OPG189: E547K"}}},{"name":"OQ503827","node_attrs":{"div":70,"accession":"OQ503827","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00404/2023"},"date":{"value":"2023-01-10"},"strain_display":{"value":"USA/OQ503827/2023-01-10"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G25309A","G28271A","G112785A","T118096C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C165231T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C180371T"],"OPG040":["S57L"],"OPG044":["D61N"],"OPG136":["M498V"],"OPG190":["S37L"]},"labels":{"aa":"OPG040: S57L; OPG044: D61N; OPG136: M498V; OPG190: S37L"}}}]},{"name":"NODE_0000142","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["T26669C","G96073A","G115235A","C125294T"],"OPG117":["D9N"]},"labels":{"aa":"OPG117: D9N"}},"children":[{"name":"OQ159027","node_attrs":{"div":69,"accession":"OQ159027","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/RKI632"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"Germany/OQ159027/2022-11-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G77052A","C135868T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP959060","node_attrs":{"div":67,"accession":"OP959060","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"lineage":{"value":"B.1.2"},"strain":{"value":"BOL-UNIMOL-MPX-293428-L"},"date":{"value":"2022-10-29"},"strain_display":{"value":"Colombia/OP959060/2022-10-29"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000143","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["C27730T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A","-196616A","-196617A"],"OPG043":["D76N"]},"labels":{"aa":"OPG043: D76N"}},"children":[{"name":"OP890528","node_attrs":{"div":65,"accession":"OP890528","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00295/2022"},"date":{"value":"2022-11-01"},"strain_display":{"value":"USA/OP890528/2022-11-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G176439A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG205":["D262N"]},"labels":{"aa":"OPG205: D262N"}}},{"name":"OQ603479","node_attrs":{"div":66,"accession":"OQ603479","author":{"author":"Haw,M.,Kath,C.,Espinosa,A.,O'Neil,R.,Hacker,J.","value":"Haw,M.,Kath,C.,Espinosa,A.,O'Neil,R.,Hacker,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDPH, VRDL"},"lineage":{"value":"B.1.2"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000210/2023"},"date":{"value":"2022-07-09"},"strain_display":{"value":"USA/OQ603479/2022-07-09"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G130555A","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","G149400A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG151":["M544I"]},"labels":{"aa":"OPG151: M544I"}}}]},{"name":"NODE_0000144","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T157527C","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}},"children":[{"name":"OP415265","node_attrs":{"div":68,"accession":"OP415265","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPX_7eECz2_9000326"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415265/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C46023T","C114099T","G149805A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G166317A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG133":["R533Q"],"OPG175":["E122K"],"OPG191":["D53N"]},"labels":{"aa":"OPG133: R533Q; OPG175: E122K; OPG191: D53N"}}},{"name":"OP555483","node_attrs":{"div":65,"accession":"OP555483","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.2"},"strain":{"value":"Monkeypox/PT0387/2022"},"date":{"value":"2022-07-12"},"strain_display":{"value":"Portugal/OP555483/2022-07-12"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G154098A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"]}}},{"name":"OR449642","node_attrs":{"div":64,"accession":"OR449642","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV/Germany/2022/ON/RKI928"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449642/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}}]},{"name":"NODE_0000145","node_attrs":{"div":69,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.2"}},"branch_attrs":{"mutations":{"nuc":["G8638A","C21548T","C47820T","C68218T","C188236T","C188339T"],"OPG037":["D296N"],"OPG085":["R105Q"]},"labels":{"aa":"OPG037: D296N; OPG085: R105Q"}},"children":[{"name":"OR427347","node_attrs":{"div":71,"accession":"OR427347","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/USA/WA-UW-025109/2023"},"date":{"value":"2023-02-XX"},"strain_display":{"value":"USA/OR427347/2023-02-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","G12239A","G12488A","-196615A"],"OPG023":["S138L","S221F"]},"labels":{"aa":"OPG023: S138L, S221F"}}},{"name":"OR427346","node_attrs":{"div":69,"accession":"OR427346","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/USA/WA-UW-048416/2023"},"date":{"value":"2023-04-XX"},"strain_display":{"value":"USA/OR427346/2023-04-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-"]}}},{"name":"OR427341","node_attrs":{"div":71,"accession":"OR427341","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.2"},"strain":{"value":"MpxV/human/USA/WA-UW-039072/2023"},"date":{"value":"2023-03-XX"},"strain_display":{"value":"USA/OR427341/2023-03-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G156482A","C175867T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG205":["S71F"]},"labels":{"aa":"OPG205: S71F"}}},{"name":"OR464212","node_attrs":{"div":70,"accession":"OR464212","author":{"author":"Gigante,C.,Goldoft,M.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Holshue,M.,Li,Y.","value":"Gigante,C.,Goldoft,M.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Holshue,M.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.2"},"strain":{"value":"MPXV_USA_2022_WA0018"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR464212/2022-12-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","T126424A","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"],"OPG148":["S147T"]},"labels":{"aa":"OPG148: S147T"}}}]}]}]},{"name":"NODE_0000146","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C25644T","-179172C","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C"]},"labels":{"clade":"B.1.7"}},"children":[{"name":"ON843170","node_attrs":{"div":62,"accession":"ON843170","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.7"},"strain":{"value":"Monkeypox/PT0031/2022"},"date":{"value":"2022-05-26"},"strain_display":{"value":"Portugal/ON843170/2022-05-26"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"]}}},{"name":"OP205081","node_attrs":{"div":62,"accession":"OP205081","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_UK_2022_9000078"},"date":{"value":"2022-06-14"},"strain_display":{"value":"United Kingdom/OP205081/2022-06-14"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179173A","-179174T","-179175T","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP415238","node_attrs":{"div":63,"accession":"OP415238","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPX_GGr0lD_9000276"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP415238/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","C39935T","-179173A","-179174T","-179175T","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OQ547747","node_attrs":{"div":62,"accession":"OQ547747","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/ON/RKI720"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ547747/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150551-","G150568-","A150569-","T150570-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OQ702773","node_attrs":{"div":64,"accession":"OQ702773","author":{"author":"Gigante,C.,Berns,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Carpenter-Azevedo,K.,Li,Y.","value":"Gigante,C.,Berns,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Carpenter-Azevedo,K.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_USA_2022_RI0005"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OQ702773/2022-07-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G98456A","C103258T","-179173A","-179174T","-179175T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A"],"OPG118":["G4E"],"OPG123":["D605N"]},"labels":{"aa":"OPG118: G4E; OPG123: D605N"}}},{"name":"OR264460","node_attrs":{"div":64,"accession":"OR264460","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.7"},"strain":{"value":"7_B"},"date":{"value":"2022-07-11"},"strain_display":{"value":"Australia/OR264460/2022-07-11"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G144556A","C170573T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}}},{"name":"OR264376","node_attrs":{"div":64,"accession":"OR264376","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.7"},"strain":{"value":"23_A"},"date":{"value":"2022-08-18"},"strain_display":{"value":"Australia/OR264376/2022-08-18"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","G46562A","T76084-","T76085-","C98821T","-179173A","-179174T","-179175T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG044":["K147-"],"OPG118":["R126C"]},"labels":{"aa":"OPG044: K147-; OPG118: R126C"}}},{"name":"NODE_0000147","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G63147A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}},"children":[{"name":"ON918611","node_attrs":{"div":67,"accession":"ON918611","author":{"author":"Chan,W.Y.,Mtshali,S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J.","value":"Chan,W.Y.,Mtshali,S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"South Africa"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute for Communicable Disease, Sequencing Core Facility"},"lineage":{"value":"B.1.7"},"strain":{"value":"NICD-SVPL223"},"date":{"value":"2022-06-20"},"strain_display":{"value":"South Africa/ON918611/2022-06-20"},"region":{"value":"Africa"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","G10224A","G129761A","T143625A","C177847T","C179172-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","-196615A"],"OPG021":["R213Q"],"OPG151":["D280N"],"OPG165":["I37N"],"OPG205":["S731L"]},"labels":{"aa":"OPG021: R213Q; OPG151: D280N; OPG165: I37N; OPG205: S731L"}}},{"name":"OP536776","node_attrs":{"div":65,"accession":"OP536776","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.7"},"strain":{"value":"9000398"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536776/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C157854T","C164272T","-179173A","-179174T","-179175T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A190779-","C190780-","T190781-","G190782-","A190783-","A190784-","A190785-","T190786-","T190787-"],"OPG016":["T124-","E125-","I126-"],"OPG189":["R314C"]},"labels":{"aa":"OPG016: T124-, E125-, I126-; OPG189: R314C"}}}]},{"name":"NODE_0000148","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C14077T","-179173A","-179174T","-179175T","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP205084","node_attrs":{"div":65,"accession":"OP205084","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_UK_2022_9000093"},"date":{"value":"2022-05-30"},"strain_display":{"value":"United Kingdom/OP205084/2022-05-30"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C4529T","G155585A","G192681A"],"OPG003":["D27N"],"OPG003_dup":["D27N"]},"labels":{"aa":"OPG003: D27N; OPG003_dup: D27N"}}},{"name":"OP415197","node_attrs":{"div":66,"accession":"OP415197","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPX_2v76E1_9000221"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"United Kingdom/OP415197/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G41557A","G91376A","G105860A"],"OPG061":["P110S"],"OPG112":["D44N"]},"labels":{"aa":"OPG061: P110S; OPG112: D44N"}}}]},{"name":"NODE_0000149","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G120241A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"],"OPG137":["D214N"]},"labels":{"aa":"OPG137: D214N"}},"children":[{"name":"ON911481","node_attrs":{"div":66,"accession":"ON911481","author":{"author":"Galan-Huerta,K.A.,Paz-Infanzon,M.,Ruiz-Higareda,A.F.,Nuzzolo-Shihadeh,L.,Camacho-Ortiz,A.,Bocanegra-Ibarias,P.,Rivas-Estilla,A.M.,Zacarias-Villarreal,D.,Yamallel-Ortega,L.A.,Guerrero-Putz,M.D.,Ocampo-Candiani,J.","value":"Galan-Huerta,K.A.,Paz-Infanzon,M.,Ruiz-Higareda,A.F.,Nuzzolo-Shihadeh,L.,Camacho-Ortiz,A.,Bocanegra-Ibarias,P.,Rivas-Estilla,A.M.,Zacarias-Villarreal,D.,Yamallel-Ortega,L.A.,Guerrero-Putz,M.D.,Ocampo-Candiani,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Mexico"},"clade_membership":{"value":"IIb"},"institution":{"value":"Universidad Autonoma de Nuevo Leon - Facultad de Medicina, Centro de Investigacion e Innovacion en Virologia Medica"},"lineage":{"value":"B.1.7"},"strain":{"value":"Monkeypox/MX-UANL001/2022"},"date":{"value":"2022-06-28"},"strain_display":{"value":"Mexico/ON911481/2022-06-28"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","G57088A","C127530T","T133098-","T133099-","T133100-","T133101-","T133102-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","T168120C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG074":["S13L"],"OPG149":["S112L"],"OPG193":["F263L"]},"labels":{"aa":"OPG074: S13L; OPG149: S112L; OPG193: F263L"}}},{"name":"OP935994","node_attrs":{"div":63,"accession":"OP935994","author":{"author":"Bajwa,M.I.,Miller,H.","value":"Bajwa,M.I.,Miller,H."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Delaware Public Health Lab, Sequencing/Bioinformatics"},"lineage":{"value":"B.1.7"},"strain":{"value":"B1118431"},"date":{"value":"2022-09-27"},"strain_display":{"value":"USA/OP935994/2022-09-27"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"NODE_0000150","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C168226T","C175467T"]}},"children":[{"name":"OP484682","node_attrs":{"div":65,"accession":"OP484682","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/RKI361"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP484682/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OQ547765","node_attrs":{"div":65,"accession":"OQ547765","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/ON/RKI738"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OQ547765/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150563-","T150564-","G150565-","A150566-","T150567-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}}]}]},{"name":"NODE_0000151","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C148771T"],"OPG174":["D209N"]},"labels":{"aa":"OPG174: D209N"}},"children":[{"name":"OR449630","node_attrs":{"div":65,"accession":"OR449630","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/ON/RKI916"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449630/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G69840A","C99542T","G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG118":["S366F"],"OPG193":["F263-"]},"labels":{"aa":"OPG118: S366F; OPG193: F263-"}}},{"name":"NODE_0000152","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G114316A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG133":["H461Y"]},"labels":{"aa":"OPG133: H461Y"}},"children":[{"name":"OR087006","node_attrs":{"div":68,"accession":"OR087006","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/UZ_REGA_197/Belgium/2022"},"date":{"value":"2022-08-03"},"strain_display":{"value":"Belgium/OR087006/2022-08-03"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C12637T","G53377A","T133102-","C178569T","-179173A","-179174T","-179175T","-179191A","-179192T","-179193T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C182707T"],"OPG210":["S451F"]},"labels":{"aa":"OPG210: S451F"}}},{"name":"NODE_0000153","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G152437A"]}},"children":[{"name":"OQ159026","node_attrs":{"div":66,"accession":"OQ159026","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/RKI631"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"Germany/OQ159026/2022-10-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150547A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","G187677A"]}}},{"name":"OQ627928","node_attrs":{"div":65,"accession":"OQ627928","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Italy"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"lineage":{"value":"B.1.7"},"strain":{"value":"INMI-19442022"},"date":{"value":"2022-09-14"},"strain_display":{"value":"Italy/OQ627928/2022-09-14"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-608T","G610-","T611-","A612-"]}}}]}]}]},{"name":"NODE_0000154","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["G42504A","-179173A","-179174T","-179175T"]}},"children":[{"name":"OP205076","node_attrs":{"div":63,"accession":"OP205076","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_UK_2022_9000070"},"date":{"value":"2022-06-09"},"strain_display":{"value":"United Kingdom/OP205076/2022-06-09"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP204840","node_attrs":{"div":64,"accession":"OP204840","author":{"author":"Seang,S.,Burrel,S.,Todesco,E.,Leducq,V.,Monsel,G.,Le Pluart,D.,Cordevant,C.,Pourcher,V.,Palich,R.,Charpentier,C.","value":"Seang,S.,Burrel,S.,Todesco,E.,Leducq,V.,Monsel,G.,Le Pluart,D.,Cordevant,C.,Pourcher,V.,Palich,R.,Charpentier,C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"APHP Pitie Salpetriere SU, Virology"},"lineage":{"value":"B.1.7"},"strain":{"value":"PatientMPXV"},"date":{"value":"2022-06-10"},"strain_display":{"value":"France/OP204840/2022-06-10"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G163250A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196612-","A196613-","A196614-"]}}},{"name":"OR463715","node_attrs":{"div":64,"accession":"OR463715","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Germany/2022/ON/RKI768"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OR463715/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C159741T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","A181253-"]}}},{"name":"NODE_0000155","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C115870T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"]}},"children":[{"name":"OP414322","node_attrs":{"div":64,"accession":"OP414322","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.7"},"strain":{"value":"Monkeypox/PT0287/2022"},"date":{"value":"2022-06-10"},"strain_display":{"value":"Portugal/OP414322/2022-06-10"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-196615A"]}}},{"name":"NODE_0000156","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C5292T","G11924A","G74267A","A161784T","G191918A"],"OPG015":["D289N"],"OPG015_dup":["D289N"],"OPG023":["S326L"],"OPG094":["R163Q"]},"labels":{"aa":"OPG015: D289N; OPG015_dup: D289N; OPG023: S326L; OPG094: R163Q"}},"children":[{"name":"OP245331","node_attrs":{"div":68,"accession":"OP245331","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPX/PT0077/2022"},"date":{"value":"2022-07-28"},"strain_display":{"value":"Portugal/OP245331/2022-07-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP555568","node_attrs":{"div":70,"accession":"OP555568","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.7"},"strain":{"value":"Monkeypox/PT0493/2022"},"date":{"value":"2022-08-11"},"strain_display":{"value":"Portugal/OP555568/2022-08-11"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G125379A","G176342A"],"OPG145":["R478K"]},"labels":{"aa":"OPG145: R478K"}}}]}]}]},{"name":"NODE_0000157","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C57173T","C179172-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"]}},"children":[{"name":"OP727822","node_attrs":{"div":70,"accession":"OP727822","author":{"author":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K.","value":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"lineage":{"value":"B.1.7"},"strain":{"value":"PrEV_case_2"},"date":{"value":"2022-10-02"},"strain_display":{"value":"Belgium/OP727822/2022-10-02"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T604-","T605-","T606-","C11401T","C33964T","C36267T","G110285A","T133102-","C144366T","A174924T","G180608A","A188351-","G195316A"],"OPG052":["R11Q"],"OPG055":["D273N"],"OPG209":["E31K"]},"labels":{"aa":"OPG052: R11Q; OPG055: D273N; OPG209: E31K"}}},{"name":"NODE_0000158","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C142797T"],"OPG164":["S7L"]},"labels":{"aa":"OPG164: S7L"}},"children":[{"name":"OP279036","node_attrs":{"div":64,"accession":"OP279036","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"lineage":{"value":"B.1.7"},"strain":{"value":"MpxV/human/CAN/UN-NML-4112/2022"},"date":{"value":"2022-06-30"},"strain_display":{"value":"Canada/OP279036/2022-06-30"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP378695","node_attrs":{"div":64,"accession":"OP378695","author":{"author":"Gigante,C.M.,Hauser,J.R.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y.","value":"Gigante,C.M.,Hauser,J.R.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_USA_2022_DC0010"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP378695/2022-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T4775-","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP480419","node_attrs":{"div":69,"accession":"OP480419","author":{"author":"Deanhardt,B.,Miller,M.,Wang,J.R.","value":"Deanhardt,B.,Miller,M.,Wang,J.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of North Carolina at Chapel Hill, Department of Genetics"},"lineage":{"value":"B.1.7"},"strain":{"value":"hMPXV/USA/NC-UNC-0020/2022"},"date":{"value":"2022-08-30"},"strain_display":{"value":"USA/OP480419/2022-08-30"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C23868T","A31053G","C128717T","G143512A","C173533A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG039":["G84E"],"OPG047":["C48R"]},"labels":{"aa":"OPG039: G84E; OPG047: C48R"}}},{"name":"OP920699","node_attrs":{"div":70,"accession":"OP920699","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00361/2022"},"date":{"value":"2022-10-31"},"strain_display":{"value":"USA/OP920699/2022-10-31"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G105325A","C108658T","G111379A","C149889T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G165395A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G184244A"],"OPG124":["S215F"],"OPG130":["S175L"],"OPG190":["E92K"]},"labels":{"aa":"OPG124: S215F; OPG130: S175L; OPG190: E92K"}}},{"name":"OR264396","node_attrs":{"div":69,"accession":"OR264396","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.7"},"strain":{"value":"33_A"},"date":{"value":"2022-09-07"},"strain_display":{"value":"Australia/OR264396/2022-09-07"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G14622A","A28529-","A28530-","T76084-","T76085-","G101241A","T133102-","C136244T","C156446T","G174708A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG025":["R216C"],"OPG044":["K147-"],"OPG153":["R475K"],"OPG204":["M59I"]},"labels":{"aa":"OPG025: R216C; OPG044: K147-; OPG153: R475K; OPG204: M59I"}}},{"name":"OR209323","node_attrs":{"div":65,"accession":"OR209323","author":{"author":"Li,C.M.","value":"Li,C.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_USA_2022_NC0003"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR209323/2022-12-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","G62268A","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","A196614-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OR759196","node_attrs":{"div":64,"accession":"OR759196","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.7"},"strain":{"value":"hMpxV/Canada/ON-PHOL108/2022"},"date":{"value":"2022-07-01"},"strain_display":{"value":"Canada/OR759196/2022-07-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR759178","node_attrs":{"div":68,"accession":"OR759178","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.7"},"strain":{"value":"hMpxV/Canada/ON-PHOL090/2022"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759178/2022-09-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","G26352A","C30137T","C55072T","G130068A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"],"OPG042":["A249V"],"OPG047":["R353K"],"OPG073":["D24N"],"OPG151":["R382Q"]},"labels":{"aa":"OPG042: A249V; OPG047: R353K; OPG073: D24N; OPG151: R382Q"}}},{"name":"OR759164","node_attrs":{"div":64,"accession":"OR759164","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.7"},"strain":{"value":"hMpxV/Canada/ON-PHOL075/2022"},"date":{"value":"2022-08-01"},"strain_display":{"value":"Canada/OR759164/2022-08-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000159","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.7"}},"branch_attrs":{"mutations":{"nuc":["C55036T","C96914T","G158254A","C170381T","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179176A","-179177T","-179178A","-179179T","-179180A"],"OPG073":["E36K"],"OPG117":["S289L"],"OPG198":["S115L"]},"labels":{"aa":"OPG073: E36K; OPG117: S289L; OPG198: S115L"}},"children":[{"name":"OQ918697","node_attrs":{"div":72,"accession":"OQ918697","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00486/2023"},"date":{"value":"2023-02-18"},"strain_display":{"value":"USA/OQ918697/2023-02-18"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G73789A","C136435T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C166803T","-173302A","-173303T","-173304A","-173305T","-173306A","-173307T","-173308A","-173309T","-173310A","-173311T","-173312A","-173313T","-173314A","-173315T","-173316A","-173317T","G178559A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG094":["G4R"],"OPG192":["P25S"]},"labels":{"aa":"OPG094: G4R; OPG192: P25S"}}},{"name":"OR464216","node_attrs":{"div":68,"accession":"OR464216","author":{"author":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y.","value":"Gigante,C.,Bradley,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Anderson,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.7"},"strain":{"value":"MPXV_USA_2022_KS0007"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"USA/OR464216/2022-11-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T"]}}}]}]}]}]},{"name":"NODE_0000160","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["G74360A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179235C"],"OPG094":["R194H"]},"labels":{"aa":"OPG094: R194H","clade":"B.1.1"}},"children":[{"name":"OP055805","node_attrs":{"div":62,"accession":"OP055805","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.1"},"strain":{"value":"MpxV/human/USA/Unknown-UW-076991/2022"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"USA/OP055805/2022-07-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C133103T","-179198A","-179199C","-179200A","-179201T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON792321","node_attrs":{"div":62,"accession":"ON792321","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Switzerland"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba6450e/2022"},"date":{"value":"2022-06-02"},"strain_display":{"value":"Switzerland/ON792321/2022-06-02"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","A19360-","T19361-","C19362-","A19363-","T19364-","T19365-","A43653-","T43654-","T43655-","A49176-","A49177-","T49178-","T49179-","T49180-","T49181-","A49182-","T49183-","T49184-","A49185-","A49186-","C49187-","G49188-","G49189-","T49190-","A49191-","A49192-","T49193-","A79063-","A79064-","T79065-","T79066-","T79067-","T79068-","A79069-","A79070-","T79071-","A79072-","T79073-","A79074-","A79075-","T79076-","A79077-","C79078-","T79079-","T79080-","A79081-","A79082-","A79083-","A79084-","A79085-","T79086-","G79087-","G79088-","A79089-","T79090-","G79091-","T79092-","T79093-","G79094-","T79095-","G79096-","T79097-","C79098-","G79099-","T79100-","T79101-","A79102-","A152691-","A152692-","T152693-","G152694-","A152695-","C152696-","G152697-","T152698-","A175944-","T175945-","A175946-","T175947-","C175948-","A175949-","A175950-","C179127A","C179136T","T179138A","T179148-","T179157-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","C179190T","-179198A","-179199C","-179200A","-179201T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T180493-","A180494-","T180495-","C180496-","A180497-","T180498-","T180499-"],"OPG063":["D50-"],"OPG068":["N329-","G330-","N331-","T332-","F333-","I334-"],"OPG205":["I97-","S98-","I99-"]},"labels":{"aa":"OPG063: D50-; OPG068: N329-, G330-, N331-, T332-, F333-, I334-; OPG205: I97-, S98-, I99-"}}},{"name":"ON694337","node_attrs":{"div":63,"accession":"ON694337","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/RKI020"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/ON694337/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C152033T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179235-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP303785","node_attrs":{"div":62,"accession":"OP303785","author":{"author":"Gigante,C.M.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.M.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV_USA_2022_IL0042"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"USA/OP303785/2022-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179235-"]}}},{"name":"OP204857","node_attrs":{"div":64,"accession":"OP204857","author":{"author":"Rhie,G.-E.","value":"Rhie,G.-E."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"South Korea"},"clade_membership":{"value":"IIb"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV-ROK-P1-2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"South Korea/OP204857/2022-08-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C786T","C71728T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G173429A","-179198A","-179199C","-179200A","-179201T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG091":["A120V"]},"labels":{"aa":"OPG091: A120V"}}},{"name":"OP382488","node_attrs":{"div":63,"accession":"OP382488","author":{"author":"Colson,P.","value":"Colson,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMPXV-IHU00011"},"date":{"value":"2022-07-19"},"strain_display":{"value":"France/OP382488/2022-07-19"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C153387T","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP536800","node_attrs":{"div":62,"accession":"OP536800","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.1"},"strain":{"value":"9000426"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP536800/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179198A","-179199C","-179200A","-179201T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T190786-","T190787-","A196614-"]}}},{"name":"OP837475","node_attrs":{"div":64,"accession":"OP837475","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Colombia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"lineage":{"value":"B.1.1"},"strain":{"value":"DC_INS_MPX_1009_L"},"date":{"value":"2022-09-19"},"strain_display":{"value":"Colombia/OP837475/2022-09-19"},"region":{"value":"South America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C17764T","G54336A","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG030":["D24N"],"OPG071":["P35S"]},"labels":{"aa":"OPG030: D24N; OPG071: P35S"}}},{"name":"OP894029","node_attrs":{"div":67,"accession":"OP894029","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI609"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP894029/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C3850T","C93296T","G117944A","G143995A","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","T150567-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155986A","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179235-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"],"OPG003":["R253Q"]},"labels":{"aa":"OPG003: R253Q"}}},{"name":"OQ427112","node_attrs":{"div":65,"accession":"OQ427112","author":{"author":"Gigante,C.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y.","value":"Gigante,C.,Buttery,E.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Raman,D.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV_USA_2022_NV0005"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"USA/OQ427112/2022-10-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C11401T","C72269T","T133102-","A136552-","T136553-","C136554-","G140194A","G158318A","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179235-"],"OPG092":["D227N"],"OPG153":["D385-"],"OPG159":["D143N"],"OPG160":["S294L"]},"labels":{"aa":"OPG092: D227N; OPG153: D385-; OPG159: D143N; OPG160: S294L"}}},{"name":"OR264399","node_attrs":{"div":64,"accession":"OR264399","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.1"},"strain":{"value":"36_A"},"date":{"value":"2022-06-30"},"strain_display":{"value":"Australia/OR264399/2022-06-30"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","A43500-","T76084-","T76085-","T80846-","T80847-","A89106-","G118500A","T121121-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","G160406A","-179198A","-179199C","-179200A","-179201T","C179235-","C196772-","A196773-","T196774-"],"OPG044":["K147-"],"OPG136":["T363M"]},"labels":{"aa":"OPG044: K147-; OPG136: T363M"}}},{"name":"OR264368","node_attrs":{"div":63,"accession":"OR264368","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.1"},"strain":{"value":"15_B"},"date":{"value":"2022-08-22"},"strain_display":{"value":"Australia/OR264368/2022-08-22"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","T76084-","T76085-","T80846-","T80847-","T121121-","T133094-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-179198A","-179199C","-179200A","-179201T","C179235-","G183484A"],"OPG044":["K147-"],"OPG210":["R710K"]},"labels":{"aa":"OPG044: K147-; OPG210: R710K"}}},{"name":"OR095036","node_attrs":{"div":65,"accession":"OR095036","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/UZ_REGA_218/Belgium/2022"},"date":{"value":"2022-08-08"},"strain_display":{"value":"Belgium/OR095036/2022-08-08"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C25828T","G107496A","G109463A","-179198A","-179199C","-179200A","-179201T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG042":["E424K"]},"labels":{"aa":"OPG042: E424K"}}},{"name":"OR500080","node_attrs":{"div":71,"accession":"OR500080","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Romania"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Romania/B-18/2022"},"date":{"value":"2022-08-16"},"strain_display":{"value":"Romania/OR500080/2022-08-16"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G17189T","A55140C","T55141A","T75369C","T91506G","G121663A","T169776C","A173282G","A173284G","T174471A","G179029T","A179046T","A179081T","A179110T","T179121A","C179127T","T179129-","T179130-","T179139A","C179172A","C179190T","-179198A","-179200A","-179201T","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C179672A","C181209T"],"OPG073":["M1W"],"OPG074":["N662M"],"OPG208":["S136Y"]},"labels":{"aa":"OPG073: M1W; OPG074: N662M; OPG208: S136Y"}}},{"name":"OR500078","node_attrs":{"div":62,"accession":"OR500078","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Romania"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Romania/B-8/2022"},"date":{"value":"2022-06-29"},"strain_display":{"value":"Romania/OR500078/2022-06-29"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T92388-","-179198A","-179199C","-179200A","-179201T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["F220-"]},"labels":{"aa":"OPG113: F220-"}}},{"name":"ON694329","node_attrs":{"div":62,"accession":"ON694329","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/RKI025"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/ON694329/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179235-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-","A192490-","A192491-","G192492-","T192493-","T192494-","A192495-","G192496-","T192497-","T192498-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP310042","node_attrs":{"div":62,"accession":"OP310042","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.1"},"strain":{"value":"MpxV/human/USA/WA-UW-089266/2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"USA/OP310042/2022-08-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-179198A","-179199C","-179200A","-179201T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A"]}}},{"name":"NODE_0000162","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C17048T","G93828A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177009A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179235-"],"OPG029":["D8N"],"OPG113":["E700K"],"OPG205":["E452K"]},"labels":{"aa":"OPG029: D8N; OPG113: E700K; OPG205: E452K"}},"children":[{"name":"OQ159028","node_attrs":{"div":66,"accession":"OQ159028","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/RKI633"},"date":{"value":"2022-11-XX"},"strain_display":{"value":"Germany/OQ159028/2022-11-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C41131T"],"OPG060":["E18K"]},"labels":{"aa":"OPG060: E18K"}}},{"name":"OQ735077","node_attrs":{"div":72,"accession":"OQ735077","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/PT0626/2023"},"date":{"value":"2023-03-21"},"strain_display":{"value":"Portugal/OQ735077/2023-03-21"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-609T","A615-","C616-","C10929T","C22179T","G39515A","G77076A","G129659A","C129949T","G139167A","C196638-","T196639-"],"OPG023":["E658K"],"OPG151":["E246K"]},"labels":{"aa":"OPG023: E658K; OPG151: E246K"}}}]},{"name":"NODE_0000163","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["G52232A","C119838T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG071":["S736L"]},"labels":{"aa":"OPG071: S736L"}},"children":[{"name":"OQ320518","node_attrs":{"div":65,"accession":"OQ320518","author":{"author":"Gigante,C.,Culbertson,M.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Pope,B.,Li,Y.","value":"Gigante,C.,Culbertson,M.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Pope,B.,Li,Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"CDC, DHCPP-PRB"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV_USA_2022_IN0006"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"USA/OQ320518/2022-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T22135C","A136552-","T136553-","C136554-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","-179198A","-179199C","-179200A","-179201T"],"OPG037":["H100R"],"OPG153":["D385-"]},"labels":{"aa":"OPG037: H100R; OPG153: D385-"}}},{"name":"OR427334","node_attrs":{"div":70,"accession":"OR427334","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"B.1.1"},"strain":{"value":"MpxV/human/USA/WA-UW-121247/2022"},"date":{"value":"2022-12-XX"},"strain_display":{"value":"USA/OR427334/2022-12-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","C11810T","G59218A","C63120T","G75522A","C159899T","G160110A","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","-196615A"],"OPG023":["R364K"],"OPG079":["S135L"]},"labels":{"aa":"OPG023: R364K; OPG079: S135L"}}}]},{"name":"NODE_0000164","node_attrs":{"div":68,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C46672T","C56805T","C72314T","C103216T","C127628T","T152686-","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C180857T"],"OPG066":["E253K"],"OPG074":["M107I"],"OPG092":["D212N"],"OPG123":["V619I"],"OPG149":["P145S"]},"labels":{"aa":"OPG066: E253K; OPG074: M107I; OPG092: D212N; OPG123: V619I; OPG149: P145S"}},"children":[{"name":"OR500086","node_attrs":{"div":71,"accession":"OR500086","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Romania"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Romania/B-35_R3/2023"},"date":{"value":"2023-02-15"},"strain_display":{"value":"Romania/OR500086/2023-02-15"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C42674T","G169748A","C179190T","T179192A","T179193A","-179198G","A185438C","C185439A"],"OPG063":["E339K"]},"labels":{"aa":"OPG063: E339K"}}},{"name":"OR500081","node_attrs":{"div":69,"accession":"OR500081","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Romania"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Romania/B-35_L1/2023"},"date":{"value":"2023-01-05"},"strain_display":{"value":"Romania/OR500081/2023-01-05"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C16327T","-179198A","-179199C","-179200A","-179201T"]}}}]},{"name":"NODE_0000165","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["G155698A"]}},"children":[{"name":"OR759194","node_attrs":{"div":72,"accession":"OR759194","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMpxV/Canada/ON-PHOL106/2022"},"date":{"value":"2022-07-01"},"strain_display":{"value":"Canada/OR759194/2022-07-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C7235T","C32798T","C55589T","C61706T","G115768A","T120124-","T120125-","A120126-","G120127-","A120128-","T120129-","A120130-","A120131-","T120132-","G127806A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159118A","G162726A","C177833T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179235-"],"OPG074":["E513K"],"OPG080":["V105I"],"OPG134":["D7N"],"OPG137":["L175-","D176-","N177-"],"OPG150":["E10K"],"OPG185":["D68N"]},"labels":{"aa":"OPG074: E513K; OPG080: V105I; OPG134: D7N; OPG137: L175-, D176-, N177-; OPG150: E10K; OPG185: D68N"}}},{"name":"NODE_0000166","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["G161575A","-179198A","-179199C","-179200A","-179201T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OR459775","node_attrs":{"div":66,"accession":"OR459775","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"South Korea"},"clade_membership":{"value":"IIb"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV-ROK-P002-2022"},"date":{"value":"2022-09-02"},"strain_display":{"value":"South Korea/OR459775/2022-09-02"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G14640A","C108843T","G136558C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG025":["H210Y"],"OPG153":["I370M"]},"labels":{"aa":"OPG025: H210Y; OPG153: I370M"}}},{"name":"OR086958","node_attrs":{"div":64,"accession":"OR086958","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/UZ_REGA_149/Belgium/2022"},"date":{"value":"2022-07-05"},"strain_display":{"value":"Belgium/OR086958/2022-07-05"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133102-"]}}}]}]},{"name":"NODE_0000167","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C29887T","-179198A","-179199C","-179200A","-179201T","C179235-"]}},"children":[{"name":"OR264437","node_attrs":{"div":63,"accession":"OR264437","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.1"},"strain":{"value":"56_C"},"date":{"value":"2022-09-06"},"strain_display":{"value":"Australia/OR264437/2022-09-06"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-"],"OPG044":["K147-"]},"labels":{"aa":"OPG044: K147-"}}},{"name":"OR264424","node_attrs":{"div":63,"accession":"OR264424","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.1"},"strain":{"value":"47_A"},"date":{"value":"2022-07-13"},"strain_display":{"value":"Australia/OR264424/2022-07-13"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OR264455","node_attrs":{"div":63,"accession":"OR264455","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.1"},"strain":{"value":"67_D"},"date":{"value":"2022-08-25"},"strain_display":{"value":"Australia/OR264455/2022-08-25"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T76084-","T76085-","T80846-","T80847-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-"]}}}]},{"name":"NODE_0000168","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C22739T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179235-"],"OPG038":["E141K"]},"labels":{"aa":"OPG038: E141K"}},"children":[{"name":"OP019276","node_attrs":{"div":63,"accession":"OP019276","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Austria"},"clade_membership":{"value":"IIb"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"lineage":{"value":"B.1.1"},"strain":{"value":"hMPXV/Austria/MUW1527495/2022"},"date":{"value":"2022-06-21"},"strain_display":{"value":"Austria/OP019276/2022-06-21"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP018589","node_attrs":{"div":65,"accession":"OP018589","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/RKI180"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OP018589/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C144256T","G170785A"],"OPG198":["E250K"]},"labels":{"aa":"OPG198: E250K"}}},{"name":"ON808413","node_attrs":{"div":63,"accession":"ON808413","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"lineage":{"value":"B.1.1"},"strain":{"value":"CVR_MPXV1a"},"date":{"value":"2022-05-15"},"strain_display":{"value":"United Kingdom/ON808413/2022-05-15"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP245355","node_attrs":{"div":66,"accession":"OP245355","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPX/PT0122/2022"},"date":{"value":"2022-07-15"},"strain_display":{"value":"Portugal/OP245355/2022-07-15"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G11267A","G18540A","G173727A"],"OPG023":["S545L"],"OPG031":["R97W"]},"labels":{"aa":"OPG023: S545L; OPG031: R97W"}}},{"name":"OP415188","node_attrs":{"div":64,"accession":"OP415188","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPX_dDDHx_9000207"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"United Kingdom/OP415188/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T33222-","A33223-","T33224-","T33225-","C33226-","T33227-","C33228-","A33229-","T33230-","T33231-","G33232-","C33233-","T33234-","T33235-","C144199T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG050":["S59-","N60-","E61-","N62-","I63-"]},"labels":{"aa":"OPG050: S59-, N60-, E61-, N62-, I63-"}}},{"name":"OP524005","node_attrs":{"div":63,"accession":"OP524005","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/RKI400"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP524005/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OR449685","node_attrs":{"div":65,"accession":"OR449685","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI971"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449685/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","C186124T","C189996T"],"OPG193":["F263-"],"OPG210":["S1590F"]},"labels":{"aa":"OPG193: F263-; OPG210: S1590F"}}},{"name":"NODE_0000169","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.1"}},"branch_attrs":{"mutations":{"nuc":["C22740T","C38937T"],"OPG056":["R33Q"]},"labels":{"aa":"OPG056: R33Q"}},"children":[{"name":"OP555641","node_attrs":{"div":67,"accession":"OP555641","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.1"},"strain":{"value":"Monkeypox/PT0570/2022"},"date":{"value":"2022-09-02"},"strain_display":{"value":"Portugal/OP555641/2022-09-02"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G74362A","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","T136555-","A136556-","T136557-","G136558-","A136559-","T136560-","A136561-","T136562-","C136563-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","C177240T"],"OPG094":["A195T"],"OPG153":["I370-","I371-","D372-","D373-","D374-","D375-","D376-","D377-"],"OPG205":["Q529*"]},"labels":{"aa":"OPG094: A195T; OPG153: I370-, I371-, D372-, D373-, D374-, D375-, D376-, D377-; OPG205: Q529*"}}},{"name":"OP555587","node_attrs":{"div":66,"accession":"OP555587","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.1"},"strain":{"value":"Monkeypox/PT0516/2022"},"date":{"value":"2022-08-17"},"strain_display":{"value":"Portugal/OP555587/2022-08-17"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G778-","T779-","C118523T","A196656-","A196657-"]}}}]}]}]},{"name":"NODE_0000170","node_attrs":{"div":62,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","G190660A"],"OPG016":["R84K"]},"labels":{"aa":"OPG016: R84K","clade":"B.1.3"}},"children":[{"name":"ON983168","node_attrs":{"div":62,"accession":"ON983168","author":{"author":"Chmel,M.,Pajer,P.,Nagy,A.,Zlamal,M.,Jirincova,H.,Dresler,J.,Bartos,O.","value":"Chmel,M.,Pajer,P.,Nagy,A.,Zlamal,M.,Jirincova,H.,Dresler,J.,Bartos,O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Czech Republic"},"clade_membership":{"value":"IIb"},"institution":{"value":"Military Heatlh Institute, Military Heatlh Institute in Prague"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPxV/Prague_001/2022/flye_medaka"},"date":{"value":"2022-04-28"},"strain_display":{"value":"Czech Republic/ON983168/2022-04-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T80849-","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP536795","node_attrs":{"div":62,"accession":"OP536795","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.3"},"strain":{"value":"9000421"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"United Kingdom/OP536795/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ721953","node_attrs":{"div":70,"accession":"OQ721953","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Taiwan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/human/Taiwan/110-525030/2023"},"date":{"value":"2023-03-XX"},"strain_display":{"value":"Taiwan/OQ721953/2023-03-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","C64426T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C166940T","T177665A","A177666T","A177667T","G178104T","G178290T","T178629A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","G196412A"],"OPG205":["N670K","N671F"]},"labels":{"aa":"OPG205: N670K, N671F"}}},{"name":"OR449633","node_attrs":{"div":62,"accession":"OR449633","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/ON/RKI919"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Germany/OR449633/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"NODE_0000171","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["C17196T","C39898T","C148933T","G171318A","C175241T","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG057":["D100N"],"OPG174":["E155K"],"OPG199":["E111K"],"OPG204":["S237L"]},"labels":{"aa":"OPG057: D100N; OPG174: E155K; OPG199: E111K; OPG204: S237L"}},"children":[{"name":"OP205116","node_attrs":{"div":67,"accession":"OP205116","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_UK_2022_9000158"},"date":{"value":"2022-07-07"},"strain_display":{"value":"United Kingdom/OP205116/2022-07-07"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}},{"name":"OP536779","node_attrs":{"div":67,"accession":"OP536779","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.3"},"strain":{"value":"9000403"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"United Kingdom/OP536779/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","A62041-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"]}}}]},{"name":"NODE_0000172","node_attrs":{"div":63,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["G55133A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"],"OPG074":["R665C"]},"labels":{"aa":"OPG074: R665C"}},"children":[{"name":"OQ581854","node_attrs":{"div":65,"accession":"OQ581854","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Taiwan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/human/Taiwan/109-005210/2023"},"date":{"value":"2023-02-XX"},"strain_display":{"value":"Taiwan/OQ581854/2023-02-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G152776A","G158406A","A192404-","G192405-","T192406-","A192411-"],"OPG180":["D29N"]},"labels":{"aa":"OPG180: D29N"}}},{"name":"NODE_0000173","node_attrs":{"div":64,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["C64426T"]}},"children":[{"name":"ON782055","node_attrs":{"div":66,"accession":"ON782055","author":{"author":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Spain"},"clade_membership":{"value":"IIb"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0001b/2022"},"date":{"value":"2022-05-31"},"strain_display":{"value":"Spain/ON782055/2022-05-31"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A48265T","C48296G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG068":["D22V"]},"labels":{"aa":"OPG068: D22V"}}},{"name":"ON792320","node_attrs":{"div":65,"accession":"ON792320","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Switzerland"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"lineage":{"value":"B.1.3"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba6449f/2022"},"date":{"value":"2022-06-01"},"strain_display":{"value":"Switzerland/ON792320/2022-06-01"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G159376A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG185":["D154N"]},"labels":{"aa":"OPG185: D154N"}}},{"name":"ON754984","node_attrs":{"div":64,"accession":"ON754984","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_SI2022_S3"},"date":{"value":"2022-06-XX"},"strain_display":{"value":"Slovenia/ON754984/2022-06-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A240-","-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON622722","node_attrs":{"div":65,"accession":"ON622722","outbreak":{"value":"hMPXV-1"},"country":{"value":"France"},"clade_membership":{"value":"IIb"},"institution":{"value":"Virology, GENomique EPIdemiologique das maladies Infectieuses, France"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_FR_HCL0001_2022"},"date":{"value":"2022-05-22"},"strain_display":{"value":"France/ON622722/2022-05-22"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C109627A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG129":["A460S"]},"labels":{"aa":"OPG129: A460S"}}},{"name":"ON609725","node_attrs":{"div":65,"accession":"ON609725","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Skubic,C.,Rozman,D.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Skubic,C.,Rozman,D.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia"},"lineage":{"value":"B.1.3"},"strain":{"value":"SLO"},"date":{"value":"2022-05-23"},"strain_display":{"value":"Slovenia/ON609725/2022-05-23"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T157-","-607T","G167517A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG193":["E62K"]},"labels":{"aa":"OPG193: E62K"}}},{"name":"OP205133","node_attrs":{"div":65,"accession":"OP205133","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_UK_2022_9000188"},"date":{"value":"2022-06-29"},"strain_display":{"value":"United Kingdom/OP205133/2022-06-29"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","C142545T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG163":["S115F"]},"labels":{"aa":"OPG163: S115F"}}},{"name":"OP205067","node_attrs":{"div":64,"accession":"OP205067","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"United Kingdom"},"clade_membership":{"value":"IIb"},"institution":{"value":"UKHSA, Research and Evaluation"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV_UK_2022_9000061"},"date":{"value":"2022-05-27"},"strain_display":{"value":"United Kingdom/OP205067/2022-05-27"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OP523994","node_attrs":{"div":67,"accession":"OP523994","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/RKI392"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Germany/OP523994/2022-09-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G36659A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G174642A","C190444T"],"OPG016":["S12L"],"OPG055":["A142V"],"OPG204":["M37I"]},"labels":{"aa":"OPG016: S12L; OPG055: A142V; OPG204: M37I"}}},{"name":"OP555633","node_attrs":{"div":65,"accession":"OP555633","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.3"},"strain":{"value":"Monkeypox/PT0562/2022"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Portugal/OP555633/2022-09-01"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168066T"],"OPG153":["D385-"],"OPG193":["Q245*"]},"labels":{"aa":"OPG153: D385-; OPG193: Q245*"}}},{"name":"OP555595","node_attrs":{"div":64,"accession":"OP555595","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.3"},"strain":{"value":"Monkeypox/PT0524/2022"},"date":{"value":"2022-08-18"},"strain_display":{"value":"Portugal/OP555595/2022-08-18"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP879736","node_attrs":{"div":64,"accession":"OP879736","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"lineage":{"value":"B.1.3"},"strain":{"value":"NJ-MPXV-017-rep2"},"date":{"value":"2022-06-29"},"strain_display":{"value":"USA/OP879736/2022-06-29"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ274889","node_attrs":{"div":64,"accession":"OQ274889","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/ON/RKI670"},"date":{"value":"2022-05-XX"},"strain_display":{"value":"Germany/OQ274889/2022-05-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OP894031","node_attrs":{"div":68,"accession":"OP894031","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/ON/RKI611"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Germany/OP894031/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133094-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","G144669A","G145790A","G168044A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","G181052-","C182177T"],"OPG209":["G179-"]},"labels":{"aa":"OPG209: G179-"}}},{"name":"OQ451904","node_attrs":{"div":76,"accession":"OQ451904","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2023/RKI719"},"date":{"value":"2023-01-XX"},"strain_display":{"value":"Germany/OQ451904/2023-01-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","C15969T","C17998T","G40610A","C43803T","C63879T","G70190A","G118289A","C147011T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G152776A","C159532T","G161629A","C189427T"],"OPG005":["P77S"],"OPG027":["E137K"],"OPG031":["M277I"],"OPG064":["G699E"],"OPG083":["D280N"],"OPG089":["E109K"],"OPG180":["D29N"],"OPG185":["P206S"],"OPG188":["E12K"]},"labels":{"aa":"OPG005: P77S; OPG027: E137K; OPG031: M277I; OPG064: G699E; OPG083: D280N; OPG089: E109K; OPG180: D29N; OPG185: P206S; OPG188: E12K"}}},{"name":"OR035715","node_attrs":{"div":64,"accession":"OR035715","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/UZ_REGA_109"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035715/2022-10-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"]}}},{"name":"OR035686","node_attrs":{"div":65,"accession":"OR035686","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/UZ_REGA_80"},"date":{"value":"2022-08-09"},"strain_display":{"value":"Belgium/OR035686/2022-08-09"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C22950T","T133101-","T133102-","C133161T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ773470","node_attrs":{"div":64,"accession":"OQ773470","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/Germany/2022/ON/RKI851"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Germany/OQ773470/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-"]}}},{"name":"OR353541","node_attrs":{"div":66,"accession":"OR353541","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Minnesota Department of Health, Public Health Laboratory"},"lineage":{"value":"B.1.3"},"strain":{"value":"MN-MDH-MPXV_0031"},"date":{"value":"2022-07-28"},"strain_display":{"value":"USA/OR353541/2022-07-28"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G13224A","G100344C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG024":["S2L"]},"labels":{"aa":"OPG024: S2L"}}},{"name":"OR264391","node_attrs":{"div":64,"accession":"OR264391","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Australia"},"clade_membership":{"value":"IIb"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"lineage":{"value":"B.1.3"},"strain":{"value":"2_A"},"date":{"value":"2022-08-10"},"strain_display":{"value":"Australia/OR264391/2022-08-10"},"region":{"value":"Oceania"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T80846-","T80847-","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OR134560","node_attrs":{"div":75,"accession":"OR134560","author":{"author":"Miller,H.,Bajwa,M.","value":"Miller,H.,Bajwa,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Delaware Public Health Lab, Sequencing/Bioinformatics"},"lineage":{"value":"B.1.3"},"strain":{"value":"B1221136"},"date":{"value":"2023-03-13"},"strain_display":{"value":"USA/OR134560/2023-03-13"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C19558T","G32277A","C35688T","G39140A","G55059A","G75512A","C110402T","C121161T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C170673T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179542T","C189174T"],"OPG034":["E150K"],"OPG049":["S292L"],"OPG073":["S28L"],"OPG095":["R237K"],"OPG139":["A70T"]},"labels":{"aa":"OPG034: E150K; OPG049: S292L; OPG073: S28L; OPG095: R237K; OPG139: A70T"}}},{"name":"OX248696","node_attrs":{"div":66,"accession":"OX248696","outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovakia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"lineage":{"value":"B.1.3"},"strain":{"value":"RNA"},"date":{"value":"2022-07-04"},"strain_display":{"value":"Slovakia/OX248696/2022-07-04"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","G37250A","C138080T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG155":["E138K"]},"labels":{"aa":"OPG155: E138K"}}},{"name":"OR759179","node_attrs":{"div":66,"accession":"OR759179","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Canada"},"clade_membership":{"value":"IIb"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"lineage":{"value":"B.1.3"},"strain":{"value":"hMpxV/Canada/ON-PHOL091/2022"},"date":{"value":"2022-09-01"},"strain_display":{"value":"Canada/OR759179/2022-09-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G85581A","C122502T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG107":["V24I"],"OPG143":["D272N"]},"labels":{"aa":"OPG107: V24I; OPG143: D272N"}}},{"name":"OP431827","node_attrs":{"div":64,"accession":"OP431827","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV22/human/USA-NE-176"},"date":{"value":"2022-08-15"},"strain_display":{"value":"USA/OP431827/2022-08-15"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"ON782021","node_attrs":{"div":64,"accession":"ON782021","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Finland"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPX-37/Finland/2022"},"date":{"value":"2022-05-24"},"strain_display":{"value":"Finland/ON782021/2022-05-24"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ626769","node_attrs":{"div":64,"accession":"OQ626769","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV22/human/USA-NE-250"},"date":{"value":"2022-09-01"},"strain_display":{"value":"USA/OQ626769/2022-09-01"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000174","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["T133102-","T168120C","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG193":["F263L"]},"labels":{"aa":"OPG193: F263L"}},"children":[{"name":"OP144212","node_attrs":{"div":66,"accession":"OP144212","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/ITM_pt_16/Belgium/10-Jun-2022"},"date":{"value":"2022-06-10"},"strain_display":{"value":"Belgium/OP144212/2022-06-10"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C133161T","C146824T","C157632T","T197000-"]}}},{"name":"ON950045","node_attrs":{"div":65,"accession":"ON950045","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,Van den Bossche,D.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Van Esbroeck,M.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,Van den Bossche,D.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Van Esbroeck,M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/ITM_pt_31/Belgium/27-May-2022"},"date":{"value":"2022-05-27"},"strain_display":{"value":"Belgium/ON950045/2022-05-27"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A140104-","A140105-","T140106-","A140107-","A140108-","C140109-","A140110-","A140111-","T140112-","T140113-","A140114-","T140115-","A140116-","A140117-","C140118-","A140119-","A140120-","T140121-","T140122-","A140123-","T140124-","A140125-","A140126-","C140127-","A140128-","A140129-","T140130-","T140131-","A140132-","T140133-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","A140143-","A140144-","T140145-","T140146-","G140147-","T140148-","T140149-","A140150-","T140151-","A140152-","A140153-","T140154-","A140155-","A140156-","T140157-","T140158-","A140159-","T140160-","A140161-","A140162-","T140163-","T140164-","G140165-","T140166-","T140167-","-196615A"],"OPG159":["N113-","N114-","N115-","Y116-","N117-","N118-","Y119-","N120-","N121-","Y122-","N123-","N124-","Y125-","N126-","C127-","Y128-","N129-","N130-","Y131-","N132-","C133-","Y134-"]},"labels":{"aa":"OPG159: N113-, N114-, N115-, Y116-, N117-, N118-, Y119-, N120-, N121-, Y122-, N123-, N124-, Y125-, N126-, C127-, Y128-, N129-, N130-, Y131-, N132-, C133-, Y134-"}}}]},{"name":"NODE_0000175","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["C133161T","C157632T"]}},"children":[{"name":"OP555472","node_attrs":{"div":66,"accession":"OP555472","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"B.1.3"},"strain":{"value":"Monkeypox/PT0376/2022"},"date":{"value":"2022-07-07"},"strain_display":{"value":"Portugal/OP555472/2022-07-07"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159243A"]}}},{"name":"OR086974","node_attrs":{"div":66,"accession":"OR086974","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"B.1.3"},"strain":{"value":"MPXV/UZ_REGA_165/Belgium/2022"},"date":{"value":"2022-07-27"},"strain_display":{"value":"Belgium/OR086974/2022-07-27"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G41336A","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000176","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"B.1.3"}},"branch_attrs":{"mutations":{"nuc":["-607T","C8612T","C56018T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G187156A"],"OPG074":["E370K"]},"labels":{"aa":"OPG074: E370K"}},"children":[{"name":"OP605585","node_attrs":{"div":68,"accession":"OP605585","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"lineage":{"value":"B.1.3"},"strain":{"value":"Slovenia-MPXV-44-2022"},"date":{"value":"2022-08-XX"},"strain_display":{"value":"Slovenia/OP605585/2022-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G52232A"],"OPG071":["S736L"]},"labels":{"aa":"OPG071: S736L"}}},{"name":"OP605570","node_attrs":{"div":67,"accession":"OP605570","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Slovenia"},"clade_membership":{"value":"IIb"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"lineage":{"value":"B.1.3"},"strain":{"value":"Slovenia-MPXV-28-2022"},"date":{"value":"2022-07-XX"},"strain_display":{"value":"Slovenia/OP605570/2022-07-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000179","node_attrs":{"div":65,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["G105923A","-150590G","-150593G","-150594G","-150599G","-150602G"],"OPG124":["L16F"]},"labels":{"aa":"OPG124: L16F","clade":"C.1"}},"children":[{"name":"LC753968","node_attrs":{"div":65,"accession":"LC753968","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Japan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220165"},"date":{"value":"2022-09-XX"},"strain_display":{"value":"Japan/LC753968/2022-09-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}}},{"name":"LC753969","node_attrs":{"div":65,"accession":"LC753969","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Japan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220176"},"date":{"value":"2022-10-XX"},"strain_display":{"value":"Japan/LC753969/2022-10-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T"]}}},{"name":"OR035728","node_attrs":{"div":66,"accession":"OR035728","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Belgium"},"clade_membership":{"value":"IIb"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/UZ_REGA_122"},"date":{"value":"2022-10-28"},"strain_display":{"value":"Belgium/OR035728/2022-10-28"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G149818A","G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG176":["D4N"]},"labels":{"aa":"OPG176: D4N"}}},{"name":"OQ581853","node_attrs":{"div":67,"accession":"OQ581853","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Taiwan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Taiwan/110-093831/2023"},"date":{"value":"2023-02-XX"},"strain_display":{"value":"Taiwan/OQ581853/2023-02-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T132513C","G150590-","G150593-","G150594-","G150599-","G150602-","C185069T"]}}},{"name":"NODE_0000180","node_attrs":{"div":66,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["C166940T","G193223A"]}},"children":[{"name":"OQ721952","node_attrs":{"div":73,"accession":"OQ721952","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Taiwan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Taiwan/240031000030/2023"},"date":{"value":"2023-03-XX"},"strain_display":{"value":"Taiwan/OQ721952/2023-03-XX"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C798T","C13503T","G33539A","G34948A","G40174A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G156025A","A183935G","A184219G"],"OPG025":["A589T"],"OPG054":["A350V"],"OPG057":["P8S"],"OPG210":["I860M","Y955C"]},"labels":{"aa":"OPG025: A589T; OPG054: A350V; OPG057: P8S; OPG210: I860M, Y955C"}}},{"name":"NODE_0000181","node_attrs":{"div":67,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["C3987T"]}},"children":[{"name":"LC756924","node_attrs":{"div":68,"accession":"LC756924","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Japan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220325"},"date":{"value":"2023-01-30"},"strain_display":{"value":"Japan/LC756924/2023-01-30"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C151434T"]}}},{"name":"LC760461","node_attrs":{"div":68,"accession":"LC760461","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Japan"},"clade_membership":{"value":"IIb"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220343"},"date":{"value":"2023-02-13"},"strain_display":{"value":"Japan/LC760461/2023-02-13"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["C798T","C68765T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G196412A"],"OPG086":["M33I"]},"labels":{"aa":"OPG086: M33I"}}},{"name":"OR427348","node_attrs":{"div":70,"accession":"OR427348","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"C.1"},"strain":{"value":"MpxV/human/USA/WA-UW-066957/2023"},"date":{"value":"2023-06-XX"},"strain_display":{"value":"USA/OR427348/2023-06-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G26855A","C30191T","G150590-","G150593-","G150594-","G150599-","G150602-","C155490T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG047":["R335H"]},"labels":{"aa":"OPG047: R335H"}}},{"name":"OR665166","node_attrs":{"div":72,"accession":"OR665166","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"UW Virology, Laboratory Medicine"},"lineage":{"value":"C.1"},"strain":{"value":"MpxV/human/USA/WA-UW-092809/2023"},"date":{"value":"2023-09-XX"},"strain_display":{"value":"USA/OR665166/2023-09-XX"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","G13434A","G29650A","C33332T","G37974A","C74691T","G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG025":["R612C"],"OPG046":["T27I"],"OPG050":["R26Q"],"OPG056":["S354L"]},"labels":{"aa":"OPG025: R612C; OPG046: T27I; OPG050: R26Q; OPG056: S354L"}}},{"name":"OR499979","node_attrs":{"div":70,"accession":"OR499979","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00522/2023"},"date":{"value":"2023-05-08"},"strain_display":{"value":"USA/OR499979/2023-05-08"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G11924A","C134237T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G178951A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG023":["S326L"]},"labels":{"aa":"OPG023: S326L"}}},{"name":"OR459797","node_attrs":{"div":67,"accession":"OR459797","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"South Korea"},"clade_membership":{"value":"IIb"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV-ROK-P026-2023"},"date":{"value":"2023-04-22"},"strain_display":{"value":"South Korea/OR459797/2023-04-22"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A113921-","G150590-","G150593-","G150594-","G150599-","G150602-","T169716C","G169717A","T169721A","G169775A","T169776C","A169780T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181T","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG197":["M16T","S18T","V36T","E37D"]},"labels":{"aa":"OPG197: M16T, S18T, V36T, E37D"}}},{"name":"NODE_0000182","node_attrs":{"div":69,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["C149963T","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","G184562A"],"OPG176":["S52L"]},"labels":{"aa":"OPG176: S52L"}},"children":[{"name":"OR459778","node_attrs":{"div":70,"accession":"OR459778","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"South Korea"},"clade_membership":{"value":"IIb"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV-ROK-P005-2023"},"date":{"value":"2023-03-13"},"strain_display":{"value":"South Korea/OR459778/2023-03-13"},"region":{"value":"Asia"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G85691A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000183","node_attrs":{"div":72,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["C21062T","G188348A","C188946T"],"OPG036":["M1I"]},"labels":{"aa":"OPG036: M1I"}},"children":[{"name":"OR643705","node_attrs":{"div":78,"accession":"OR643705","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"USA"},"clade_membership":{"value":"IIb"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"lineage":{"value":"C.1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00563/2023"},"date":{"value":"2023-08-16"},"strain_display":{"value":"USA/OR643705/2023-08-16"},"region":{"value":"North America"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["G21880A","G47532A","C125074T","G133704A","G133838A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T180483A"],"OPG037":["S185F"]},"labels":{"aa":"OPG037: S185F"}}},{"name":"NODE_0000184","node_attrs":{"div":75,"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"},"lineage":{"value":"C.1"}},"branch_attrs":{"mutations":{"nuc":["G101241A","C142797T","G152866A","C191053-","A191054-","T191055-","G191056-","G191057-","A191058-","G191059-","T191060-","C191061-","G191062-","G191063-","T191064-","A191065-","G191066-","A191067-","T191068-","T191069-","T191070-","C191071-","A191072-","T191073-","G191074-","G191075-","C191076-","T191077-","G191078-","T191079-","C191080-","G191081-","A191082-","T191083-","G191084-","A191085-","G191086-","C191087-","A191088-","G191089-","T191090-","T191091-","T191092-","C191093-","A191094-","C191095-","G191096-","A191097-","C191098-","G191099-","A191100-","C191101-","C191102-","T191103-","C191104-","G191105-","A191106-","T191107-","C191108-","T191109-","T191110-","T191111-","G191112-","G191113-","T191114-","C191115-","A191116-","T191117-","T191118-","A191119-","T191120-","C191121-","T191122-","T191123-","T191124-","G191125-","G191126-","T191127-","A191128-","G191129-"],"OPG164":["S7L"],"OPG180":["D59N"]},"labels":{"aa":"OPG164: S7L; OPG180: D59N"}},"children":[{"name":"OR326991","node_attrs":{"div":76,"accession":"OR326991","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/PT0627/2023"},"date":{"value":"2023-06-15"},"strain_display":{"value":"Portugal/OR326991/2023-06-15"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G165862T"]}}},{"name":"OR743499","node_attrs":{"div":77,"accession":"OR743499","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1030"},"date":{"value":"2023-10-XX"},"strain_display":{"value":"Germany/OR743499/2023-10-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T57476C","G173397A","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG075":["Q8R"]},"labels":{"aa":"OPG075: Q8R"}}},{"name":"OR519724","node_attrs":{"div":75,"accession":"OR519724","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Germany"},"clade_membership":{"value":"IIb"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1022"},"date":{"value":"2023-08-XX"},"strain_display":{"value":"Germany/OR519724/2023-08-XX"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"]}}},{"name":"OR487998","node_attrs":{"div":76,"accession":"OR487998","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/PT0680/2023"},"date":{"value":"2023-08-08"},"strain_display":{"value":"Portugal/OR487998/2023-08-08"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["A176268G"],"OPG205":["S205G"]},"labels":{"aa":"OPG205: S205G"}}},{"name":"OR487980","node_attrs":{"div":78,"accession":"OR487980","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"outbreak":{"value":"hMPXV-1"},"country":{"value":"Portugal"},"clade_membership":{"value":"IIb"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"lineage":{"value":"C.1"},"strain":{"value":"MPXV/PT0656/2023"},"date":{"value":"2023-07-21"},"strain_display":{"value":"Portugal/OR487980/2023-07-21"},"region":{"value":"Europe"},"host":{"value":"Homo sapiens"}},"branch_attrs":{"mutations":{"nuc":["T606-","G13563A","C37738T","G151847A","A196614-"],"OPG025":["P569S"],"OPG056":["E433K"]},"labels":{"aa":"OPG025: P569S; OPG056: E433K"}}}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}} \ No newline at end of file diff --git a/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/CHANGELOG.md b/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/CHANGELOG.md new file mode 100644 index 00000000..bc7a66da --- /dev/null +++ b/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/CHANGELOG.md @@ -0,0 +1,12 @@ +## Unreleased + +Initial release of this dataset. This dataset is similar to the v2 dataset [`hMPXV_B.1/pseudo_ON563414`](https://github.com/nextstrain/nextclade_data/tree/2023-08-17--15-51-24--UTC/data/datasets/hMPXV_B.1/references/pseudo_ON563414/versions/2023-08-01T12%3A00%3A00Z/files) with some differences. + +### Important changes compared to v2 dataset + +- Some genes have been renamed and one has been added. The new annotation is based on NCBI refseq annotations that were released in November 2022. The v2 dataset predates this refseq. + - The 4 genes in the inverted terminal repeat segment (ITR) on both ends of the genome (OPG001, OPG002, OPG003,OPG015) are now all included. The genes on the 3' end (~positions 190000-197000) now have an `_dup` appended to distinguish them. + - The gene previously named `NBT03_gp052` is now called `OPG073` + - The gene previously named `NBT03_gp174` is now called `OPG016` + - The gene previously named `NBT03_gp175` is now called `OPG015_dup` + - Gene `OPG166` has been added diff --git a/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/README.md b/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/README.md new file mode 100644 index 00000000..bd06fb0a --- /dev/null +++ b/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/README.md @@ -0,0 +1,27 @@ +# Nextclade dataset for "Mpox virus (Lineage B.1)" + +| property | value | +| ------------------- | ------------------------------------------------------------------------------------------------------------------------------------------------------- | +| authors | [Cornelius Roemer](https://neherlab.org), [Richard Neher](https://neherlab.org), [Nextstrain](https://nextstrain.org) | +| data source | Genbank | +| workflow | [github.com/nextstrain/mpox/nextclade](https://github.com/nextstrain/mpox/nextclade) | +| issue tracker | github.com/nextstrain/mpox/issues | +| nextclade data path | nextstrain/mpox/lineage-iib/rivers +| title | Mpox virus (Lineage B.1) | +| taxon | [NCBI:txid10244](https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&id=10244) | +| annotation | [NC_063383.1](https://www.ncbi.nlm.nih.gov/nuccore/NC_063383) | +| clade definitions | github.com/mpxv-lineages/lineage-designation | +| references | [Urgent need for a non-discriminatory and non-stigmatizing nomenclature for monkeypox virus](https://doi.org/10.1371/journal.pbio.3001769) | +| related datasets | Mpox virus (All clades): `nextstrain/mpox/all-clades/rivers-with-ancestral-snps`
Mpox virus (Lineage B.1) `nextstrain/mpox/lineage-iib/rivers-with-usa-2022-ma001-snps` | + +This Nextclade dataset is intended for use with Mpox viruses that fall within clade IIb. If your sequences are all or mostly descended from the 2022 outbreak lineage B.1 you may want to use the even more specific dataset for that lineage instead: `nextstrain/mpox/lineage-iib/rivers-with-usa-2022-ma001-snps`. If you want to analyze broader Mpox diversity, i.e. also clade I or clade II, use the more general dataset `nextstrain/mpox/all-clades/rivers-with-ancestral-snps`. The more specific a dataset, the faster it will run and the less overwhelming the results will be (fewer SNPs), more relevant reference sequences will be included for tree placement. Sequences that are beyond the scope of a dataset will still be included in the results but will get assigned to the fallback clade `outgroup`. + +This dataset supports calling all designated lineages within the clade IIb (A, A.1, A.2, A.3, A.1.1, B.1, etc.). The clade and lineage nomenclature used is outlined in [Urgent need for a non-discriminatory and non-stigmatizing nomenclature for monkeypox virus](https://doi.org/10.1371/journal.pbio.3001769). The ground truth for lineage definitions is available at [github.com/mpxv-lineages/lineage-designation](https://github.com/nextstrain/mpox/nextclade). This dataset will be updated as new lineages are designated. + +The reference used in this dataset is based on mpox virus NCBI refseq NC_063383.1 (`MPXV-M5312_HM12_Rivers`). + +The sequences used for construction of the reference tree are obtained from the `/ingest` workflow of the `nextstrain/monkeypox` repo. This workflow downloads and processes sequences from NCBI/Genbank. Sequences are sampled from all clades and all lineages over time and countries for a representative sample of the diversity of Mpox virus. The sequences are then aligned with Nextclade and a maximum likelihood tree is inferred with IQ-TREE. The tree is then rooted with the reconstructed ancestral sequence and ancestral states are inferred with TreeTime. + +## Further reading + +Read more about Nextclade datasets in Nextclade documentation: https://docs.nextstrain.org/projects/nextclade/en/stable/user/datasets.html diff --git a/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/genome_annotation.gff3 b/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/genome_annotation.gff3 new file mode 100644 index 00000000..432d5465 --- /dev/null +++ b/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/genome_annotation.gff3 @@ -0,0 +1,391 @@ +##gff-version 3 +#!gff-spec-version 1.21 +#!processor NCBI annotwriter +##sequence-region NC_063383.1 1 197209 +##species https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10244 +NC_063383.1 RefSeq region 1 197209 . + . ID=NC_063383.1:1..197209;Dbxref=taxon:10244;collection-date=2018-08;country=Nigeria: Rivers State;gbkey=Src;genome=genomic;genotype=MPXV clade 2;isolate=MPXV-M5312_HM12_Rivers;mol_type=genomic DNA;nat-host=Homo sapiens +NC_063383.1 RefSeq long_terminal_repeat 1 6422 . - . ID=id-NC_063383.1:1..6422;gbkey=repeat_region;rpt_type=long_terminal_repeat +NC_063383.1 RefSeq gene 835 1575 . - . ID=gene-NBT03_gp001;Dbxref=GeneID:72551607;Name=OPG001;gbkey=Gene;gene=OPG001;gene_biotype=protein_coding;locus_tag=NBT03_gp001;old_locus_tag=MPXV-M5312_HM12_Rivers-001 +NC_063383.1 RefSeq CDS 835 1575 . - 0 ID=cds-YP_010377002.1;Parent=gene-NBT03_gp001;Dbxref=GenBank:YP_010377002.1,GeneID:72551607;Name=OPG001;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp001%3B Chemokine binding protein (Cop-C23L)%3B most abundant secreted protein%3B CC-chemokine binding%3B similar to VACV-WR J1L and VACV-Cop C23L;gbkey=CDS;gene=OPG001;locus_tag=NBT03_gp001;product=Chemokine binding protein;protein_id=YP_010377002.1 +NC_063383.1 RefSeq gene 1702 2751 . - . ID=gene-NBT03_gp002;Dbxref=GeneID:72551418;Name=OPG002;gbkey=Gene;gene=OPG002;gene_biotype=protein_coding;locus_tag=NBT03_gp002;old_locus_tag=MPXV-M5312_HM12_Rivers-002 +NC_063383.1 RefSeq CDS 1702 2751 . - 0 ID=cds-YP_010377003.1;Parent=gene-NBT03_gp002;Dbxref=GenBank:YP_010377003.1,GeneID:72551418;Name=OPG002;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: NBT03_gp002%3B TNF receptor (CrmB)%3B similar to VACV-WR J2L and VACV-Cop C22L;gbkey=CDS;gene=OPG002;locus_tag=NBT03_gp002;product=Crm-B secreted TNF-alpha-receptor-like protein;protein_id=YP_010377003.1 +NC_063383.1 RefSeq gene 2841 4607 . - . ID=gene-NBT03_gp003;Dbxref=GeneID:72551419;Name=OPG003;gbkey=Gene;gene=OPG003;gene_biotype=protein_coding;locus_tag=NBT03_gp003;old_locus_tag=MPXV-M5312_HM12_Rivers-003 +NC_063383.1 RefSeq CDS 2841 4607 . - 0 ID=cds-YP_010377004.1;Parent=gene-NBT03_gp003;Dbxref=GenBank:YP_010377004.1,GeneID:72551419;Name=OPG003;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp003%3B Ankyrin%3B similar to VACV-WR J3L and VACV-Cop C19L;gbkey=CDS;gene=OPG003;locus_tag=NBT03_gp003;product=Ankyrin repeat protein (25);protein_id=YP_010377004.1 +NC_063383.1 RefSeq gene 4843 6156 . - . ID=gene-NBT03_gp004;Dbxref=GeneID:72551420;Name=OPG015;gbkey=Gene;gene=OPG015;gene_biotype=protein_coding;locus_tag=NBT03_gp004;old_locus_tag=MPXV-M5312_HM12_Rivers-004 +NC_063383.1 RefSeq CDS 4843 6156 . - 0 ID=cds-YP_010377005.1;Parent=gene-NBT03_gp004;Dbxref=GenBank:YP_010377005.1,GeneID:72551420;Name=OPG015;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp004%3B Ankyrin%3B similar to VACV-WR D1L and CPXV-017;gbkey=CDS;gene=OPG015;locus_tag=NBT03_gp004;product=Ankyrin repeat protein (39);protein_id=YP_010377005.1 +NC_063383.1 RefSeq sequence_feature 6270 6419 . - . ID=id-NC_063383.1:6270..6419;exon_number=OPG016;gbkey=misc_feature;number=OPG016 +NC_063383.1 RefSeq sequence_feature 6444 6885 . - . ID=id-NC_063383.1:6444..6885;exon_number=OPG017;gbkey=misc_feature;number=OPG017 +NC_063383.1 RefSeq sequence_feature 6966 7463 . - . ID=id-NC_063383.1:6966..7463;exon_number=OPG018;gbkey=misc_feature;number=OPG018 +NC_063383.1 RefSeq gene 7580 8008 . + . ID=gene-NBT03_gp005;Dbxref=GeneID:72551421;Name=OPG019;gbkey=Gene;gene=OPG019;gene_biotype=protein_coding;locus_tag=NBT03_gp005;old_locus_tag=MPXV-M5312_HM12_Rivers-006 +NC_063383.1 RefSeq CDS 7580 8008 . + 0 ID=cds-YP_010377006.1;Parent=gene-NBT03_gp005;Dbxref=GenBank:YP_010377006.1,GeneID:72551421;Name=OPG019;Note=Taxonomic breadth: chordopoxvirinae%3B secreted growth factor Secreted EGF-like protein%3B similar to VACV-WR D3R and VACV-Cop C11R;gbkey=CDS;gene=OPG019;locus_tag=NBT03_gp005;product=EGF-like domain protein;protein_id=YP_010377006.1 +NC_063383.1 RefSeq sequence_feature 8136 9102 . - . ID=id-NC_063383.1:8136..9102;exon_number=OPG020;gbkey=misc_feature;number=OPG020 +NC_063383.1 RefSeq gene 9587 10315 . + . ID=gene-NBT03_gp006;Dbxref=GeneID:72551422;Name=OPG021;gbkey=Gene;gene=OPG021;gene_biotype=protein_coding;locus_tag=NBT03_gp006;old_locus_tag=MPXV-M5312_HM12_Rivers-008 +NC_063383.1 RefSeq CDS 9587 10315 . + 0 ID=cds-YP_010377007.1;Parent=gene-NBT03_gp006;Dbxref=GenBank:YP_010377007.1,GeneID:72551422;Name=OPG021;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp008%3B Zinc finger-like protein%3B zinc binding%3B virosome localization%3B virulence factor%3B inhibition of apoptosis induced by UV irradiation%3B similar to VACV-WR D5R;gbkey=CDS;gene=OPG021;locus_tag=NBT03_gp006;product=Zinc finger-like protein (2);protein_id=YP_010377007.1 +NC_063383.1 RefSeq gene 10478 10858 . - . ID=gene-NBT03_gp007;Dbxref=GeneID:72551423;Name=OPG022;gbkey=Gene;gene=OPG022;gene_biotype=protein_coding;locus_tag=NBT03_gp007;old_locus_tag=MPXV-M5312_HM12_Rivers-009 +NC_063383.1 RefSeq CDS 10478 10858 . - 0 ID=cds-YP_010377008.1;Parent=gene-NBT03_gp007;Dbxref=GenBank:YP_010377008.1,GeneID:72551423;Name=OPG022;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp009%3B secreted IL-18 binding protein%3B Soluble IL-18 binding protein (Bsh-D7L)%3B similar to VACV-WR D6L;gbkey=CDS;gene=OPG022;locus_tag=NBT03_gp007;product=Interleukin-18-binding protein;protein_id=YP_010377008.1 +NC_063383.1 RefSeq gene 10918 12900 . - . ID=gene-NBT03_gp008;Dbxref=GeneID:72551424;Name=OPG023;gbkey=Gene;gene=OPG023;gene_biotype=protein_coding;locus_tag=NBT03_gp008;old_locus_tag=MPXV-M5312_HM12_Rivers-010 +NC_063383.1 RefSeq CDS 10918 12900 . - 0 ID=cds-YP_010377009.1;Parent=gene-NBT03_gp008;Dbxref=GenBank:YP_010377009.1,GeneID:72551424;Name=OPG023;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp010%3B host range%3B ankyrin-like%3B Ankyrin/Host Range (Bang-D8L)%3B similar to VACV-WR D7L;gbkey=CDS;gene=OPG023;locus_tag=NBT03_gp008;product=Ankyrin repeat protein (2);protein_id=YP_010377009.1 +NC_063383.1 RefSeq gene 13034 13228 . - . ID=gene-NBT03_gp009;Dbxref=GeneID:72551425;Name=OPG024;gbkey=Gene;gene=OPG024;gene_biotype=protein_coding;locus_tag=NBT03_gp009;old_locus_tag=MPXV-M5312_HM12_Rivers-011 +NC_063383.1 RefSeq CDS 13034 13228 . - 0 ID=cds-YP_010377010.1;Parent=gene-NBT03_gp009;Dbxref=GenBank:YP_010377010.1,GeneID:72551425;Name=OPG024;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp011%3B ANK-containing protein%3B similar to VACV-WR D8L;gbkey=CDS;gene=OPG024;locus_tag=NBT03_gp009;product=retroviral pseudoprotease-like protein;protein_id=YP_010377010.1 +NC_063383.1 RefSeq gene 13375 15267 . - . ID=gene-NBT03_gp010;Dbxref=GeneID:72551426;Name=OPG025;gbkey=Gene;gene=OPG025;gene_biotype=protein_coding;locus_tag=NBT03_gp010;old_locus_tag=MPXV-M5312_HM12_Rivers-012 +NC_063383.1 RefSeq CDS 13375 15267 . - 0 ID=cds-YP_010377011.1;Parent=gene-NBT03_gp010;Dbxref=GenBank:YP_010377011.1,GeneID:72551426;Name=OPG025;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp012%3B ankyrin-like%3B Type I IFN resistance%3B similar to VACV-WR D9L and VACV-Cop C9L;gbkey=CDS;gene=OPG025;locus_tag=NBT03_gp010;product=Ankyrin repeat protein (14);protein_id=YP_010377011.1 +NC_063383.1 RefSeq sequence_feature 15310 15854 . - . ID=id-NC_063383.1:15310..15854;exon_number=OPG026;gbkey=misc_feature;number=OPG026 +NC_063383.1 RefSeq gene 15925 16377 . - . ID=gene-NBT03_gp011;Dbxref=GeneID:72551427;Name=OPG027;gbkey=Gene;gene=OPG027;gene_biotype=protein_coding;locus_tag=NBT03_gp011;old_locus_tag=MPXV-M5312_HM12_Rivers-013 +NC_063383.1 RefSeq CDS 15925 16377 . - 0 ID=cds-YP_010377012.1;Parent=gene-NBT03_gp011;Dbxref=GenBank:YP_010377012.1,GeneID:72551427;Name=OPG027;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp013%3B host range%3B Type 1 IFN inhibitor%3B similar to VACV-WR D10L and VACV-Cop C7L;gbkey=CDS;gene=OPG027;locus_tag=NBT03_gp011;product=Host range protein;protein_id=YP_010377012.1 +NC_063383.1 RefSeq gene 16602 17069 . - . ID=gene-NBT03_gp012;Dbxref=GeneID:72551428;Name=OPG029;gbkey=Gene;gene=OPG029;gene_biotype=protein_coding;locus_tag=NBT03_gp012;old_locus_tag=MPXV-M5312_HM12_Rivers-014 +NC_063383.1 RefSeq CDS 16602 17069 . - 0 ID=cds-YP_010377013.1;Parent=gene-NBT03_gp012;Dbxref=GenBank:YP_010377013.1,GeneID:72551428;Name=OPG029;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp014%3B Putative tlr signaling inhibitor%2C IFN-beta inhibitor%3B similar to VACV-WR D11L and VACV-Cop C6L;gbkey=CDS;gene=OPG029;locus_tag=NBT03_gp012;product=Bcl-2-like protein;protein_id=YP_010377013.1 +NC_063383.1 RefSeq gene 17213 17833 . - . ID=gene-NBT03_gp013;Dbxref=GeneID:72551429;Name=OPG030;gbkey=Gene;gene=OPG030;gene_biotype=protein_coding;locus_tag=NBT03_gp013;old_locus_tag=MPXV-M5312_HM12_Rivers-015 +NC_063383.1 RefSeq CDS 17213 17833 . - 0 ID=cds-YP_010377014.1;Parent=gene-NBT03_gp013;Dbxref=GenBank:YP_010377014.1,GeneID:72551429;Name=OPG030;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp015%3B BTB domain of kelch-like protein%3B Kelch-like protein%3B similar to VACV-WR D12L and VACV-Cop C5L;gbkey=CDS;gene=OPG030;locus_tag=NBT03_gp013;product=Kelch-like protein (1);protein_id=YP_010377014.1 +NC_063383.1 RefSeq gene 17878 18828 . - . ID=gene-NBT03_gp014;Dbxref=GeneID:72551430;Name=OPG031;gbkey=Gene;gene=OPG031;gene_biotype=protein_coding;locus_tag=NBT03_gp014;old_locus_tag=MPXV-M5312_HM12_Rivers-016 +NC_063383.1 RefSeq CDS 17878 18828 . - 0 ID=cds-YP_010377015.1;Parent=gene-NBT03_gp014;Dbxref=GenBank:YP_010377015.1,GeneID:72551430;Name=OPG031;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp016%3B IL-1 receptor antagonist%3B similar to VACV-WR D13L and VACV-Cop C10L;gbkey=CDS;gene=OPG031;locus_tag=NBT03_gp014;product=C4L/C10L-like family protein;protein_id=YP_010377015.1 +NC_063383.1 RefSeq sequence_feature 18902 19288 . - . ID=id-NC_063383.1:18902..19288;exon_number=OPG033;gbkey=misc_feature;number=OPG033 +NC_063383.1 RefSeq gene 19361 20005 . - . ID=gene-NBT03_gp015;Dbxref=GeneID:72551431;Name=OPG034;gbkey=Gene;gene=OPG034;gene_biotype=protein_coding;locus_tag=NBT03_gp015;old_locus_tag=MPXV-M5312_HM12_Rivers-018 +NC_063383.1 RefSeq CDS 19361 20005 . - 0 ID=cds-YP_010377017.1;Parent=gene-NBT03_gp015;Dbxref=GenBank:YP_010377017.1,GeneID:72551431;Name=OPG034;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp022%3B Putative TLR signalling inhibitor%3B start of ORF is missing approx. 18 AA compared to CPXVs%3B similar to VACV-WR D19L and VACV-Cop C1L;gbkey=CDS;gene=OPG034;locus_tag=NBT03_gp015;product=Bcl-2-like protein;protein_id=YP_010377017.1 +NC_063383.1 RefSeq gene 20051 20404 . - . ID=gene-NBT03_gp016;Dbxref=GeneID:72551432;Name=OPG035;gbkey=Gene;gene=OPG035;gene_biotype=protein_coding;locus_tag=NBT03_gp016;old_locus_tag=MPXV-M5312_HM12_Rivers-019 +NC_063383.1 RefSeq CDS 20051 20404 . - 0 ID=cds-YP_010377018.1;Parent=gene-NBT03_gp016;Dbxref=GenBank:YP_010377018.1,GeneID:72551432;Name=OPG035;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp023%3B secreted virulence factor%3B Putative tlr signaling inhibitor%3B Anti-apoptotic Bcl-2-like protein%3B similar to VACV-WR P1L and VACV-Cop N1L;gbkey=CDS;gene=OPG035;locus_tag=NBT03_gp016;product=Bcl-2-like protein;protein_id=YP_010377018.1 +NC_063383.1 RefSeq gene 20531 21064 . - . ID=gene-NBT03_gp017;Dbxref=GeneID:72551433;Name=OPG036;gbkey=Gene;gene=OPG036;gene_biotype=protein_coding;locus_tag=NBT03_gp017;old_locus_tag=MPXV-M5312_HM12_Rivers-020 +NC_063383.1 RefSeq CDS 20531 21064 . - 0 ID=cds-YP_010377019.1;Parent=gene-NBT03_gp017;Dbxref=GenBank:YP_010377019.1,GeneID:72551433;Name=OPG036;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp024%3B Alpha amanatin target protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR P2L and VACV-Cop #N2L;gbkey=CDS;gene=OPG036;locus_tag=NBT03_gp017;product=Bcl-2-like protein;protein_id=YP_010377019.1 +NC_063383.1 RefSeq gene 21105 22433 . - . ID=gene-NBT03_gp018;Dbxref=GeneID:72551434;Name=OPG037;gbkey=Gene;gene=OPG037;gene_biotype=protein_coding;locus_tag=NBT03_gp018;old_locus_tag=MPXV-M5312_HM12_Rivers-021 +NC_063383.1 RefSeq CDS 21105 22433 . - 0 ID=cds-YP_010377020.1;Parent=gene-NBT03_gp018;Dbxref=GenBank:YP_010377020.1,GeneID:72551434;Name=OPG037;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp025%3B ankyrin-like%3B ANK-containing protein%3B apoptosis inhibitor%3B start of ORF is missing approx. 31 AA compared to CPXVs%3B similar to VACV-WR O1L and VACV-Cop M1L;gbkey=CDS;gene=OPG037;locus_tag=NBT03_gp018;product=Ankyrin-like protein (1);protein_id=YP_010377020.1 +NC_063383.1 RefSeq gene 22497 23159 . - . ID=gene-NBT03_gp019;Dbxref=GeneID:72551435;Name=OPG038;gbkey=Gene;gene=OPG038;gene_biotype=protein_coding;locus_tag=NBT03_gp019;old_locus_tag=MPXV-M5312_HM12_Rivers-022 +NC_063383.1 RefSeq CDS 22497 23159 . - 0 ID=cds-YP_010377021.1;Parent=gene-NBT03_gp019;Dbxref=GenBank:YP_010377021.1,GeneID:72551435;Name=OPG038;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp026%3B NFkB inhibitor%3B similar to VACV-WR O2L and VACV-Cop M2L;gbkey=CDS;gene=OPG038;locus_tag=NBT03_gp019;product=NFkB inhibitor;protein_id=YP_010377021.1 +NC_063383.1 RefSeq gene 23264 24118 . - . ID=gene-NBT03_gp020;Dbxref=GeneID:72551436;Name=OPG039;gbkey=Gene;gene=OPG039;gene_biotype=protein_coding;locus_tag=NBT03_gp020;old_locus_tag=MPXV-M5312_HM12_Rivers-023 +NC_063383.1 RefSeq CDS 23264 24118 . - 0 ID=cds-YP_010377022.1;Parent=gene-NBT03_gp020;Dbxref=GenBank:YP_010377022.1,GeneID:72551436;Name=OPG039;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp027%3B host range%3B ankyrin-like%3B Ankyrin/NFkB inhibitor%3B similar to VACV-WR C1L and VACV-Cop K1L;gbkey=CDS;gene=OPG039;locus_tag=NBT03_gp020;product=Ankyrin-like protein (3);protein_id=YP_010377022.1 +NC_063383.1 RefSeq gene 24351 25478 . - . ID=gene-NBT03_gp021;Dbxref=GeneID:72551437;Name=OPG040;gbkey=Gene;gene=OPG040;gene_biotype=protein_coding;locus_tag=NBT03_gp021;old_locus_tag=MPXV-M5312_HM12_Rivers-024 +NC_063383.1 RefSeq CDS 24351 25478 . - 0 ID=cds-YP_010377023.1;Parent=gene-NBT03_gp021;Dbxref=GenBank:YP_010377023.1,GeneID:72551437;Name=OPG040;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp028%3B serine protease inhibitor-like%2C SPI-3%3B inhibition of the ability of infected cells to fuse%3B Serpin 1%2C2%2C3%3B similar to VACV-WR C2L and VACV-Cop K2L;gbkey=CDS;gene=OPG040;locus_tag=NBT03_gp021;product=Serpin;protein_id=YP_010377023.1 +NC_063383.1 RefSeq sequence_feature 25529 25767 . - . ID=id-NC_063383.1:25529..25767;exon_number=OPG041;gbkey=misc_feature;number=OPG041 +NC_063383.1 RefSeq gene 25823 27097 . - . ID=gene-NBT03_gp022;Dbxref=GeneID:72551438;Name=OPG042;gbkey=Gene;gene=OPG042;gene_biotype=protein_coding;locus_tag=NBT03_gp022;old_locus_tag=MPXV-M5312_HM12_Rivers-026 +NC_063383.1 RefSeq CDS 25823 27097 . - 0 ID=cds-YP_010377025.1;Parent=gene-NBT03_gp022;Dbxref=GenBank:YP_010377025.1,GeneID:72551438;Name=OPG042;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp030%3B phospholipase D-like%3B Phospholipase-D-like protein%3B similar to VACV-WR C4L and VACV-Cop K4L;gbkey=CDS;gene=OPG042;locus_tag=NBT03_gp022;product=Phospholipase-D-like protein;protein_id=YP_010377025.1 +NC_063383.1 RefSeq gene 27125 27955 . - . ID=gene-NBT03_gp023;Dbxref=GeneID:72551439;Name=OPG043;gbkey=Gene;gene=OPG043;gene_biotype=protein_coding;locus_tag=NBT03_gp023;old_locus_tag=MPXV-M5312_HM12_Rivers-027 +NC_063383.1 RefSeq CDS 27125 27955 . - 0 ID=cds-YP_010377026.1;Parent=gene-NBT03_gp023;Dbxref=GenBank:YP_010377026.1,GeneID:72551439;Name=OPG043;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp031%3B lysophospholipase-like%3B Monoglyceride lipase%3B similar to VACV-WR C5L and VACV-Cop K5L;gbkey=CDS;gene=OPG043;locus_tag=NBT03_gp023;product=Putative monoglyceride lipase;protein_id=YP_010377026.1 +NC_063383.1 RefSeq gene 28091 28540 . + . ID=gene-NBT03_gp024;Dbxref=GeneID:72551440;Name=OPG044;gbkey=Gene;gene=OPG044;gene_biotype=protein_coding;locus_tag=NBT03_gp024;old_locus_tag=MPXV-M5312_HM12_Rivers-028 +NC_063383.1 RefSeq CDS 28091 28540 . + 0 ID=cds-YP_010377027.1;Parent=gene-NBT03_gp024;Dbxref=GenBank:YP_010377027.1,GeneID:72551440;Name=OPG044;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp032%3B Putative tlr signaling inhibitor%3B Host immune response repressor%3B similar to VACV-WR C6R and VACV-Cop #K7R;gbkey=CDS;gene=OPG044;locus_tag=NBT03_gp024;product=Bcl-2-like protein;protein_id=YP_010377027.1 +NC_063383.1 RefSeq gene 28603 29262 . - . ID=gene-NBT03_gp025;Dbxref=GeneID:72551441;Name=OPG045;gbkey=Gene;gene=OPG045;gene_biotype=protein_coding;locus_tag=NBT03_gp025;old_locus_tag=MPXV-M5312_HM12_Rivers-029 +NC_063383.1 RefSeq CDS 28603 29262 . - 0 ID=cds-YP_010377028.1;Parent=gene-NBT03_gp025;Dbxref=GenBank:YP_010377028.1,GeneID:72551441;Name=OPG045;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp033%3B Caspase-9 (apoptosis) inhibitor (mitochondrial- associated)%3B similar to VACV-WR C7L and VACV-Cop F1L;gbkey=CDS;gene=OPG045;locus_tag=NBT03_gp025;product=Caspase-9 inhibitor;protein_id=YP_010377028.1 +NC_063383.1 RefSeq gene 29274 29729 . - . ID=gene-NBT03_gp026;Dbxref=GeneID:72551442;Name=OPG046;gbkey=Gene;gene=OPG046;gene_biotype=protein_coding;locus_tag=NBT03_gp026;old_locus_tag=MPXV-M5312_HM12_Rivers-030 +NC_063383.1 RefSeq CDS 29274 29729 . - 0 ID=cds-YP_010377029.1;Parent=gene-NBT03_gp026;Dbxref=GenBank:YP_010377029.1,GeneID:72551442;Name=OPG046;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp034%3B deoxyuridine triphosphatase%3B dUTPase%3B similar to VACV-WR C8L and VACV-Cop F2L;gbkey=CDS;gene=OPG046;locus_tag=NBT03_gp026;product=dUTPase;protein_id=YP_010377029.1 +NC_063383.1 RefSeq gene 29746 31194 . - . ID=gene-NBT03_gp027;Dbxref=GeneID:72551443;Name=OPG047;gbkey=Gene;gene=OPG047;gene_biotype=protein_coding;locus_tag=NBT03_gp027;old_locus_tag=MPXV-M5312_HM12_Rivers-031 +NC_063383.1 RefSeq CDS 29746 31194 . - 0 ID=cds-YP_010377030.1;Parent=gene-NBT03_gp027;Dbxref=GenBank:YP_010377030.1,GeneID:72551443;Name=OPG047;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp035%3B kelch-like%3B Kelch-like protein%3B similar to VACV-WR C9L and VACV-Cop F3L;gbkey=CDS;gene=OPG047;locus_tag=NBT03_gp027;product=Kelch-like protein (2);protein_id=YP_010377030.1 +NC_063383.1 RefSeq gene 31205 32164 . - . ID=gene-NBT03_gp028;Dbxref=GeneID:72551444;Name=OPG048;gbkey=Gene;gene=OPG048;gene_biotype=protein_coding;locus_tag=NBT03_gp028;old_locus_tag=MPXV-M5312_HM12_Rivers-032 +NC_063383.1 RefSeq CDS 31205 32164 . - 0 ID=cds-YP_010377031.1;Parent=gene-NBT03_gp028;Dbxref=GenBank:YP_010377031.1,GeneID:72551444;Name=OPG048;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp036%3B Ribonucleotide reductase small subunit%2C R2%3B similar to VACV-WR C10L and VACV-Cop F4L;gbkey=CDS;gene=OPG048;locus_tag=NBT03_gp028;product=Ribonucleotide reductase small subunit;protein_id=YP_010377031.1 +NC_063383.1 RefSeq gene 32195 33151 . - . ID=gene-NBT03_gp029;Dbxref=GeneID:72551445;Name=OPG049;gbkey=Gene;gene=OPG049;gene_biotype=protein_coding;locus_tag=NBT03_gp029;old_locus_tag=MPXV-M5312_HM12_Rivers-033 +NC_063383.1 RefSeq CDS 32195 33151 . - 0 ID=cds-YP_010377032.1;Parent=gene-NBT03_gp029;Dbxref=GenBank:YP_010377032.1,GeneID:72551445;Name=OPG049;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp037%3B 36kDa major membrane protein%3B similar to VACV-WR C11L and VACV-Cop F5L;gbkey=CDS;gene=OPG049;locus_tag=NBT03_gp029;product=Telomere-binding protein I6 (1);protein_id=YP_010377032.1 +NC_063383.1 RefSeq gene 33181 33408 . - . ID=gene-NBT03_gp030;Dbxref=GeneID:72551446;Name=OPG050;gbkey=Gene;gene=OPG050;gene_biotype=protein_coding;locus_tag=NBT03_gp030;old_locus_tag=MPXV-M5312_HM12_Rivers-034 +NC_063383.1 RefSeq CDS 33181 33408 . - 0 ID=cds-YP_010377033.1;Parent=gene-NBT03_gp030;Dbxref=GenBank:YP_010377033.1,GeneID:72551446;Name=OPG050;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp038%3B Hypothetical protein%3B similar to VACV-WR C12L and VACV-Cop F6L;gbkey=CDS;gene=OPG050;locus_tag=NBT03_gp030;product=CPXV053 protein;protein_id=YP_010377033.1 +NC_063383.1 RefSeq gene 33425 33649 . - . ID=gene-NBT03_gp031;Dbxref=GeneID:72551447;Name=OPG051;gbkey=Gene;gene=OPG051;gene_biotype=protein_coding;locus_tag=NBT03_gp031;old_locus_tag=MPXV-M5312_HM12_Rivers-035 +NC_063383.1 RefSeq CDS 33425 33649 . - 0 ID=cds-YP_010377034.1;Parent=gene-NBT03_gp031;Dbxref=GenBank:YP_010377034.1,GeneID:72551447;Name=OPG051;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp039%3B Hypothetical protein%3B similar to VACV-WR C13L and VACV-Cop F7L;gbkey=CDS;gene=OPG051;locus_tag=NBT03_gp031;product=CPXV054 protein;protein_id=YP_010377034.1 +NC_063383.1 RefSeq gene 33801 33995 . - . ID=gene-NBT03_gp032;Dbxref=GeneID:72551448;Name=OPG052;gbkey=Gene;gene=OPG052;gene_biotype=protein_coding;locus_tag=NBT03_gp032;old_locus_tag=MPXV-M5312_HM12_Rivers-036 +NC_063383.1 RefSeq CDS 33801 33995 . - 0 ID=cds-YP_010377035.1;Parent=gene-NBT03_gp032;Dbxref=GenBank:YP_010377035.1,GeneID:72551448;Name=OPG052;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp040%3B Cytoplasmic protein%3B similar to VACV-WR C14L and VACV-Cop F8L;gbkey=CDS;gene=OPG052;locus_tag=NBT03_gp032;product=Cytoplasmic protein;protein_id=YP_010377035.1 +NC_063383.1 RefSeq gene 34052 34690 . - . ID=gene-NBT03_gp033;Dbxref=GeneID:72551449;Name=OPG053;gbkey=Gene;gene=OPG053;gene_biotype=protein_coding;locus_tag=NBT03_gp033;old_locus_tag=MPXV-M5312_HM12_Rivers-037 +NC_063383.1 RefSeq CDS 34052 34690 . - 0 ID=cds-YP_010377036.1;Parent=gene-NBT03_gp033;Dbxref=GenBank:YP_010377036.1,GeneID:72551449;Name=OPG053;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp041%3B S-S bond formation pathway protein substrate%3B similar to VACV-WR C15L and VACV-Cop F9L;gbkey=CDS;gene=OPG053;locus_tag=NBT03_gp033;product=IMV membrane protein L1R;protein_id=YP_010377036.1 +NC_063383.1 RefSeq gene 34677 35996 . - . ID=gene-NBT03_gp034;Dbxref=GeneID:72551450;Name=OPG054;gbkey=Gene;gene=OPG054;gene_biotype=protein_coding;locus_tag=NBT03_gp034;old_locus_tag=MPXV-M5312_HM12_Rivers-038 +NC_063383.1 RefSeq CDS 34677 35996 . - 0 ID=cds-YP_010377037.1;Parent=gene-NBT03_gp034;Dbxref=GenBank:YP_010377037.1,GeneID:72551450;Name=OPG054;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp042%3B serine%3B Essential Ser/Thr kinase morph%3B similar to VACV-WR C16L and VACV-Cop F10L;gbkey=CDS;gene=OPG054;locus_tag=NBT03_gp034;product=Serine/threonine-protein kinase;protein_id=YP_010377037.1 +NC_063383.1 RefSeq gene 36019 37083 . - . ID=gene-NBT03_gp035;Dbxref=GeneID:72551451;Name=OPG055;gbkey=Gene;gene=OPG055;gene_biotype=protein_coding;locus_tag=NBT03_gp035;old_locus_tag=MPXV-M5312_HM12_Rivers-039 +NC_063383.1 RefSeq CDS 36019 37083 . - 0 ID=cds-YP_010377038.1;Parent=gene-NBT03_gp035;Dbxref=GenBank:YP_010377038.1,GeneID:72551451;Name=OPG055;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp043%3B RhoA signalling inhibitor%2C virus release protein%3B MC018%3B similar to VACV-WR C17L and VACV-Cop F11L;gbkey=CDS;gene=OPG055;locus_tag=NBT03_gp035;product=Protein F11;protein_id=YP_010377038.1 +NC_063383.1 RefSeq gene 37127 39034 . - . ID=gene-NBT03_gp036;Dbxref=GeneID:72551452;Name=OPG056;gbkey=Gene;gene=OPG056;gene_biotype=protein_coding;locus_tag=NBT03_gp036;old_locus_tag=MPXV-M5312_HM12_Rivers-040 +NC_063383.1 RefSeq CDS 37127 39034 . - 0 ID=cds-YP_010377039.1;Parent=gene-NBT03_gp036;Dbxref=GenBank:YP_010377039.1,GeneID:72551452;Name=OPG056;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp044%3B actin tail formation%3B EEV maturation protein%3B similar to VACV-WR C18L and VACV-Cop F12L;gbkey=CDS;gene=OPG056;locus_tag=NBT03_gp036;product=EEV maturation protein;protein_id=YP_010377039.1 +NC_063383.1 RefSeq gene 39077 40195 . - . ID=gene-NBT03_gp037;Dbxref=GeneID:72551453;Name=OPG057;gbkey=Gene;gene=OPG057;gene_biotype=protein_coding;locus_tag=NBT03_gp037;old_locus_tag=MPXV-M5312_HM12_Rivers-041 +NC_063383.1 RefSeq CDS 39077 40195 . - 0 ID=cds-YP_010377040.1;Parent=gene-NBT03_gp037;Dbxref=GenBank:YP_010377040.1,GeneID:72551453;Name=OPG057;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp045%3B major envelope antigen of EEV%3B wrapping of IMV to form IEV%3B phospholipase D-like%3B Palmitylated EEV membrane glycoprotein%3B similar to VACV-WR C19L and VACV-Cop F13L;gbkey=CDS;gene=OPG057;locus_tag=NBT03_gp037;product=Palmytilated EEV membrane protein;protein_id=YP_010377040.1 +NC_063383.1 RefSeq gene 40213 40434 . - . ID=gene-NBT03_gp038;Dbxref=GeneID:72551454;Name=OPG058;gbkey=Gene;gene=OPG058;gene_biotype=protein_coding;locus_tag=NBT03_gp038;old_locus_tag=MPXV-M5312_HM12_Rivers-042 +NC_063383.1 RefSeq CDS 40213 40434 . - 0 ID=cds-YP_010377041.1;Parent=gene-NBT03_gp038;Dbxref=GenBank:YP_010377041.1,GeneID:72551454;Name=OPG058;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp046%3B similar to VACV-WR C20L and VACV-Cop F14L;gbkey=CDS;gene=OPG058;locus_tag=NBT03_gp038;product=Protein F14 (1);protein_id=YP_010377041.1 +NC_063383.1 RefSeq gene 40484 40633 . - . ID=gene-NBT03_gp039;Dbxref=GeneID:72551455;Name=OPG059;gbkey=Gene;gene=OPG059;gene_biotype=protein_coding;locus_tag=NBT03_gp039;old_locus_tag=MPXV-M5312_HM12_Rivers-043 +NC_063383.1 RefSeq CDS 40484 40633 . - 0 ID=cds-YP_010377042.1;Parent=gene-NBT03_gp039;Dbxref=GenBank:YP_010377042.1,GeneID:72551455;Name=OPG059;Note=Taxonomic breadth: poxvirinae%3B IMV protein%3B C20.5L%3B similar to VACV-CopF14.5L;gbkey=CDS;gene=OPG059;locus_tag=NBT03_gp039;product=Cytochrome C oxidase;protein_id=YP_010377042.1 +NC_063383.1 RefSeq gene 40706 41182 . - . ID=gene-NBT03_gp040;Dbxref=GeneID:72551456;Name=OPG060;gbkey=Gene;gene=OPG060;gene_biotype=protein_coding;locus_tag=NBT03_gp040;old_locus_tag=MPXV-M5312_HM12_Rivers-044 +NC_063383.1 RefSeq CDS 40706 41182 . - 0 ID=cds-YP_010377043.1;Parent=gene-NBT03_gp040;Dbxref=GenBank:YP_010377043.1,GeneID:72551456;Name=OPG060;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp047%3B Unknown conserved protein%3B similar to VACV-WR C21L and VACV-Cop F15L;gbkey=CDS;gene=OPG060;locus_tag=NBT03_gp040;product=Protein F15;protein_id=YP_010377043.1 +NC_063383.1 RefSeq gene 41189 41884 . - . ID=gene-NBT03_gp041;Dbxref=GeneID:72551457;Name=OPG061;gbkey=Gene;gene=OPG061;gene_biotype=protein_coding;locus_tag=NBT03_gp041;old_locus_tag=MPXV-M5312_HM12_Rivers-045 +NC_063383.1 RefSeq CDS 41189 41884 . - 0 ID=cds-YP_010377044.1;Parent=gene-NBT03_gp041;Dbxref=GenBank:YP_010377044.1,GeneID:72551457;Name=OPG061;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp048%3B Non-functional Serine Recombinase%3B similar to VACV-WR C22L and VACV-Cop F16L;gbkey=CDS;gene=OPG061;locus_tag=NBT03_gp041;product=Protein F16 (1);protein_id=YP_010377044.1 +NC_063383.1 RefSeq gene 41947 42252 . + . ID=gene-NBT03_gp042;Dbxref=GeneID:72551458;Name=OPG062;gbkey=Gene;gene=OPG062;gene_biotype=protein_coding;locus_tag=NBT03_gp042;old_locus_tag=MPXV-M5312_HM12_Rivers-046 +NC_063383.1 RefSeq CDS 41947 42252 . + 0 ID=cds-YP_010377045.1;Parent=gene-NBT03_gp042;Dbxref=GenBank:YP_010377045.1,GeneID:72551458;Name=OPG062;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp049%3B virion core DNA-binding phosphoprotein (VP11)%3B mTOR antagonist%3B similar to VACV-WR C23R and VACV-Cop F17R;gbkey=CDS;gene=OPG062;locus_tag=NBT03_gp042;product=DNA-binding phosphoprotein (1);protein_id=YP_010377045.1 +NC_063383.1 RefSeq gene 42249 43688 . - . ID=gene-NBT03_gp043;Dbxref=GeneID:72551459;Name=OPG063;gbkey=Gene;gene=OPG063;gene_biotype=protein_coding;locus_tag=NBT03_gp043;old_locus_tag=MPXV-M5312_HM12_Rivers-047 +NC_063383.1 RefSeq CDS 42249 43688 . - 0 ID=cds-YP_010377046.1;Parent=gene-NBT03_gp043;Dbxref=GenBank:YP_010377046.1,GeneID:72551459;Name=OPG063;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp050%3B poly-A polymerase%2C Poly (A) polymerase catalytic subunit (VP55)%3B similar to VACV-WR F1L and VACV-Cop E1L;gbkey=CDS;gene=OPG063;locus_tag=NBT03_gp043;product=Poly(A) polymerase catalytic subunit (3);protein_id=YP_010377046.1 +NC_063383.1 RefSeq gene 43685 45898 . - . ID=gene-NBT03_gp044;Dbxref=GeneID:72551460;Name=OPG064;gbkey=Gene;gene=OPG064;gene_biotype=protein_coding;locus_tag=NBT03_gp044;old_locus_tag=MPXV-M5312_HM12_Rivers-048 +NC_063383.1 RefSeq CDS 43685 45898 . - 0 ID=cds-YP_010377047.1;Parent=gene-NBT03_gp044;Dbxref=GenBank:YP_010377047.1,GeneID:72551460;Name=OPG064;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp051%3B IEV morphogenesis%3B similar to VACV-WR F2L and VACV-Cop E2L;gbkey=CDS;gene=OPG064;locus_tag=NBT03_gp044;product=Iev morphogenesis protein;protein_id=YP_010377047.1 +NC_063383.1 RefSeq gene 46022 46483 . - . ID=gene-NBT03_gp045;Dbxref=GeneID:72551461;Name=OPG065;gbkey=Gene;gene=OPG065;gene_biotype=protein_coding;locus_tag=NBT03_gp045;old_locus_tag=MPXV-M5312_HM12_Rivers-049 +NC_063383.1 RefSeq CDS 46022 46483 . - 0 ID=cds-YP_010377048.1;Parent=gene-NBT03_gp045;Dbxref=GenBank:YP_010377048.1,GeneID:72551461;Name=OPG065;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp052%3B interferon resistance factor%3B two forms (25 kDa and 19 kDa) of the dsRNA-binding protein%3B inhibition of dsRNA-dependent protein kinase and 2-5A-synthet%3B dsRNA-binding protein%2C IFN resistance/PKR inhibitor (Z-DNA binding)%3B start of ORF is missing approx. 37 AA compared to CPXVs%3B similar to VACV-WR F3L and VACV-Cop E3L;gbkey=CDS;gene=OPG065;locus_tag=NBT03_gp045;product=Double-stranded RNA binding protein;protein_id=YP_010377048.1 +NC_063383.1 RefSeq gene 46649 47428 . - . ID=gene-NBT03_gp046;Dbxref=GeneID:72551462;Name=OPG066;gbkey=Gene;gene=OPG066;gene_biotype=protein_coding;locus_tag=NBT03_gp046;old_locus_tag=MPXV-M5312_HM12_Rivers-050 +NC_063383.1 RefSeq CDS 46649 47428 . - 0 ID=cds-YP_010377049.1;Parent=gene-NBT03_gp046;Dbxref=GenBank:YP_010377049.1,GeneID:72551462;Name=OPG066;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp053%3B RNA polymerase 30 kDa subunit (RPO30)%3B simultaneously intermediate stage promoter-specific transcription factor%2C VITF-1%3B similar to VACV-WR F4L and VACV-Cop E4L;gbkey=CDS;gene=OPG066;locus_tag=NBT03_gp046;product=DNA-directed RNA polymerase 30 kDa polypeptide;protein_id=YP_010377049.1 +NC_063383.1 RefSeq sequence_feature 47525 48062 . + . ID=id-NC_063383.1:47525..48062;exon_number=OPG067;gbkey=misc_feature;number=OPG067 +NC_063383.1 RefSeq gene 48201 49904 . + . ID=gene-NBT03_gp047;Dbxref=GeneID:72551463;Name=OPG068;gbkey=Gene;gene=OPG068;gene_biotype=protein_coding;locus_tag=NBT03_gp047;old_locus_tag=MPXV-M5312_HM12_Rivers-052 +NC_063383.1 RefSeq CDS 48201 49904 . + 0 ID=cds-YP_010377051.1;Parent=gene-NBT03_gp047;Dbxref=GenBank:YP_010377051.1,GeneID:72551463;Name=OPG068;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp054%3B Virion protein%3B similar to VACV-WR F5R and VACV-Cop E6R;gbkey=CDS;gene=OPG068;locus_tag=NBT03_gp047;product=IMV membrane protein E6;protein_id=YP_010377051.1 +NC_063383.1 RefSeq gene 49986 50486 . + . ID=gene-NBT03_gp048;Dbxref=GeneID:72551464;Name=OPG069;gbkey=Gene;gene=OPG069;gene_biotype=protein_coding;locus_tag=NBT03_gp048;old_locus_tag=MPXV-M5312_HM12_Rivers-053 +NC_063383.1 RefSeq CDS 49986 50486 . + 0 ID=cds-YP_010377052.1;Parent=gene-NBT03_gp048;Dbxref=GenBank:YP_010377052.1,GeneID:72551464;Name=OPG069;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp055%3B soluble myristylated protein%3B similar to VACV-WR F6R and VACV-Cop E7R;gbkey=CDS;gene=OPG069;locus_tag=NBT03_gp048;product=Myristoylated protein E7;protein_id=YP_010377052.1 +NC_063383.1 RefSeq gene 50590 51411 . + . ID=gene-NBT03_gp049;Dbxref=GeneID:72551465;Name=OPG070;gbkey=Gene;gene=OPG070;gene_biotype=protein_coding;locus_tag=NBT03_gp049;old_locus_tag=MPXV-M5312_HM12_Rivers-054 +NC_063383.1 RefSeq CDS 50590 51411 . + 0 ID=cds-YP_010377053.1;Parent=gene-NBT03_gp049;Dbxref=GenBank:YP_010377053.1,GeneID:72551465;Name=OPG070;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp056%3B ER-localized membrane protein%2C virion core protein%3B similar to VACV-WR F7R and VACV-Cop E8R;gbkey=CDS;gene=OPG070;locus_tag=NBT03_gp049;product=Membrane protein E8;protein_id=YP_010377053.1 +NC_063383.1 RefSeq gene 51418 54438 . - . ID=gene-NBT03_gp050;Dbxref=GeneID:72551466;Name=OPG071;gbkey=Gene;gene=OPG071;gene_biotype=protein_coding;locus_tag=NBT03_gp050;old_locus_tag=MPXV-M5312_HM12_Rivers-055 +NC_063383.1 RefSeq CDS 51418 54438 . - 0 ID=cds-YP_010377054.1;Parent=gene-NBT03_gp050;Dbxref=GenBank:YP_010377054.1,GeneID:72551466;Name=OPG071;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp057%3B DNA polymerase%2C catalytic subunit%3B similar to VACV-WR F8L and VACV-Cop E9L;gbkey=CDS;gene=OPG071;locus_tag=NBT03_gp050;product=DNA polymerase (2);protein_id=YP_010377054.1 +NC_063383.1 RefSeq gene 54470 54757 . + . ID=gene-NBT03_gp051;Dbxref=GeneID:72551467;Name=OPG072;gbkey=Gene;gene=OPG072;gene_biotype=protein_coding;locus_tag=NBT03_gp051;old_locus_tag=MPXV-M5312_HM12_Rivers-056 +NC_063383.1 RefSeq CDS 54470 54757 . + 0 ID=cds-YP_010377055.1;Parent=gene-NBT03_gp051;Dbxref=GenBank:YP_010377055.1,GeneID:72551467;Name=OPG072;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp058%3B protein disulfide bond-forming enzyme%3B Sulfhydryl oxidase (FAD-linked)%3B similar to VACV-WR F9R and VACV-Cop E10R;gbkey=CDS;gene=OPG072;locus_tag=NBT03_gp051;product=Sulfhydryl oxidase;protein_id=YP_010377055.1 +NC_063383.1 RefSeq gene 54752 55141 . - . ID=gene-NBT03_gp052;Dbxref=GeneID:72551468;Name=OPG073;gbkey=Gene;gene=OPG073;gene_biotype=protein_coding;locus_tag=NBT03_gp052;old_locus_tag=MPXV-M5312_HM12_Rivers-057 +NC_063383.1 RefSeq CDS 54752 55141 . - 0 ID=cds-YP_010377056.1;Parent=gene-NBT03_gp052;Dbxref=GenBank:YP_010377056.1,GeneID:72551468;Name=OPG073;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp059%3B virion core protein%3B similar to VACV-WR F10L and VACV-Cop E11L;gbkey=CDS;gene=OPG073;locus_tag=NBT03_gp052;product=Virion core protein E11;protein_id=YP_010377056.1 +NC_063383.1 RefSeq gene 55128 57125 . - . ID=gene-NBT03_gp053;Dbxref=GeneID:72551469;Name=OPG074;gbkey=Gene;gene=OPG074;gene_biotype=protein_coding;locus_tag=NBT03_gp053;old_locus_tag=MPXV-M5312_HM12_Rivers-058 +NC_063383.1 RefSeq CDS 55128 57125 . - 0 ID=cds-YP_010377057.1;Parent=gene-NBT03_gp053;Dbxref=GenBank:YP_010377057.1,GeneID:72551469;Name=OPG074;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp060%3B Membrane protein%3B similar to VACV-WR Q1L and VACV-Cop O1L;gbkey=CDS;gene=OPG074;locus_tag=NBT03_gp053;product=Iev morphogenesis protein;protein_id=YP_010377057.1 +NC_063383.1 RefSeq gene 57172 57498 . - . ID=gene-NBT03_gp054;Dbxref=GeneID:72551470;Name=OPG075;gbkey=Gene;gene=OPG075;gene_biotype=protein_coding;locus_tag=NBT03_gp054;old_locus_tag=MPXV-M5312_HM12_Rivers-059 +NC_063383.1 RefSeq CDS 57172 57498 . - 0 ID=cds-YP_010377058.1;Parent=gene-NBT03_gp054;Dbxref=GenBank:YP_010377058.1,GeneID:72551470;Name=OPG075;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp061%3B virion-associated glutaredoxin%3B glutaredoxin 1%3B similar to VACV-WR Q2L and VACV-Cop O2L;gbkey=CDS;gene=OPG075;locus_tag=NBT03_gp054;product=Glutaredoxin-1;protein_id=YP_010377058.1 +NC_063383.1 RefSeq gene 57523 57630 . - . ID=gene-NBT03_gp055;Dbxref=GeneID:72551471;Name=OPG076;gbkey=Gene;gene=OPG076;gene_biotype=protein_coding;locus_tag=NBT03_gp055 +NC_063383.1 RefSeq CDS 57523 57630 . - 0 ID=cds-YP_010377183.1;Parent=gene-NBT03_gp055;Dbxref=GenBank:YP_010377183.1,GeneID:72551471;Name=OPG076;gbkey=CDS;gene=OPG076;locus_tag=NBT03_gp055;product=MV membrane EFC component;protein_id=YP_010377183.1 +NC_063383.1 RefSeq gene 57645 58583 . - . ID=gene-NBT03_gp056;Dbxref=GeneID:72551472;Name=OPG077;gbkey=Gene;gene=OPG077;gene_biotype=protein_coding;locus_tag=NBT03_gp056;old_locus_tag=MPXV-M5312_HM12_Rivers-060 +NC_063383.1 RefSeq CDS 57645 58583 . - 0 ID=cds-YP_010377059.1;Parent=gene-NBT03_gp056;Dbxref=GenBank:YP_010377059.1,GeneID:72551472;Name=OPG077;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp062%3B virosomal protein essential for virus multiplication%3B DNA-binding core protein%3B similar to VACV-WR I1L and VACV-Cop I1L;gbkey=CDS;gene=OPG077;locus_tag=NBT03_gp056;product=Telomere-binding protein I1;protein_id=YP_010377059.1 +NC_063383.1 RefSeq gene 58590 58811 . - . ID=gene-NBT03_gp057;Dbxref=GeneID:72551473;Name=OPG078;gbkey=Gene;gene=OPG078;gene_biotype=protein_coding;locus_tag=NBT03_gp057;old_locus_tag=MPXV-M5312_HM12_Rivers-061 +NC_063383.1 RefSeq CDS 58590 58811 . - 0 ID=cds-YP_010377060.1;Parent=gene-NBT03_gp057;Dbxref=GenBank:YP_010377060.1,GeneID:72551473;Name=OPG078;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp063%3B IMV membrane protein%3B similar to VACV-WR I2L and VACV-Cop I2L;gbkey=CDS;gene=OPG078;locus_tag=NBT03_gp057;product=IMV membrane protein I2;protein_id=YP_010377060.1 +NC_063383.1 RefSeq gene 58812 59621 . - . ID=gene-NBT03_gp058;Dbxref=GeneID:72551474;Name=OPG079;gbkey=Gene;gene=OPG079;gene_biotype=protein_coding;locus_tag=NBT03_gp058;old_locus_tag=MPXV-M5312_HM12_Rivers-062 +NC_063383.1 RefSeq CDS 58812 59621 . - 0 ID=cds-YP_010377061.1;Parent=gene-NBT03_gp058;Dbxref=GenBank:YP_010377061.1,GeneID:72551474;Name=OPG079;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp064%3B virosomal ssDNA-binding phosphoprotein%3B interacts with R2 subunit of ribonucleotide reductase%3B similar to VACV-WR I3L and VACV-Cop I3L;gbkey=CDS;gene=OPG079;locus_tag=NBT03_gp058;product=DNA-binding phosphoprotein (2);protein_id=YP_010377061.1 +NC_063383.1 RefSeq gene 59703 62018 . - . ID=gene-NBT03_gp059;Dbxref=GeneID:72551475;Name=OPG080;gbkey=Gene;gene=OPG080;gene_biotype=protein_coding;locus_tag=NBT03_gp059;old_locus_tag=MPXV-M5312_HM12_Rivers-063 +NC_063383.1 RefSeq CDS 59703 62018 . - 0 ID=cds-YP_010377062.1;Parent=gene-NBT03_gp059;Dbxref=GenBank:YP_010377062.1,GeneID:72551475;Name=OPG080;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp065%3B ribonucleotide reductase%2C large subunit%2C R1%3B similar to VACV-WR I4L and VACV-Cop I4L;gbkey=CDS;gene=OPG080;locus_tag=NBT03_gp059;product=Ribonucleoside-diphosphate reductase (2);protein_id=YP_010377062.1 +NC_063383.1 RefSeq gene 62046 62285 . - . ID=gene-NBT03_gp060;Dbxref=GeneID:72551476;Name=OPG081;gbkey=Gene;gene=OPG081;gene_biotype=protein_coding;locus_tag=NBT03_gp060;old_locus_tag=MPXV-M5312_HM12_Rivers-064 +NC_063383.1 RefSeq CDS 62046 62285 . - 0 ID=cds-YP_010377063.1;Parent=gene-NBT03_gp060;Dbxref=GenBank:YP_010377063.1,GeneID:72551476;Name=OPG081;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp066%3B IMV surface membrane protein%2C VP13%3B similar to VACV-WR I5L and VACV-Cop I5L;gbkey=CDS;gene=OPG081;locus_tag=NBT03_gp060;product=IMV membrane protein I5;protein_id=YP_010377063.1 +NC_063383.1 RefSeq gene 62304 63452 . - . ID=gene-NBT03_gp061;Dbxref=GeneID:72551477;Name=OPG082;gbkey=Gene;gene=OPG082;gene_biotype=protein_coding;locus_tag=NBT03_gp061;old_locus_tag=MPXV-M5312_HM12_Rivers-065 +NC_063383.1 RefSeq CDS 62304 63452 . - 0 ID=cds-YP_010377064.1;Parent=gene-NBT03_gp061;Dbxref=GenBank:YP_010377064.1,GeneID:72551477;Name=OPG082;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp067%3B Telomere-binding protein%3B similar to VACV-WR I6L and VACV-Cop I6L;gbkey=CDS;gene=OPG082;locus_tag=NBT03_gp061;product=Telomere-binding protein;protein_id=YP_010377064.1 +NC_063383.1 RefSeq gene 63445 64716 . - . ID=gene-NBT03_gp062;Dbxref=GeneID:72551478;Name=OPG083;gbkey=Gene;gene=OPG083;gene_biotype=protein_coding;locus_tag=NBT03_gp062;old_locus_tag=MPXV-M5312_HM12_Rivers-066 +NC_063383.1 RefSeq CDS 63445 64716 . - 0 ID=cds-YP_010377065.1;Parent=gene-NBT03_gp062;Dbxref=GenBank:YP_010377065.1,GeneID:72551478;Name=OPG083;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp068%3B virion core protein%3B similar to DNA topoisomerase II%3B Virion core cysteine protease%3B similar to VACV-WR I7L and VACV-Cop I7L;gbkey=CDS;gene=OPG083;locus_tag=NBT03_gp062;product=Viral core cysteine proteinase;protein_id=YP_010377065.1 +NC_063383.1 RefSeq gene 64722 66752 . + . ID=gene-NBT03_gp063;Dbxref=GeneID:72551479;Name=OPG084;gbkey=Gene;gene=OPG084;gene_biotype=protein_coding;locus_tag=NBT03_gp063;old_locus_tag=MPXV-M5312_HM12_Rivers-067 +NC_063383.1 RefSeq CDS 64722 66752 . + 0 ID=cds-YP_010377066.1;Parent=gene-NBT03_gp063;Dbxref=GenBank:YP_010377066.1,GeneID:72551479;Name=OPG084;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp069%3B nucleoside triphosphate phosphohydrolase II%2C NPH-II%3B DNA and RNA helicase%3B DExH-NPH-II domain%3B similar to VACV-WR I8R and VACV-Cop I8R;gbkey=CDS;gene=OPG084;locus_tag=NBT03_gp063;product=RNA helicase NPH-II (2);protein_id=YP_010377066.1 +NC_063383.1 RefSeq gene 66756 68531 . - . ID=gene-NBT03_gp064;Dbxref=GeneID:72551480;Name=OPG085;gbkey=Gene;gene=OPG085;gene_biotype=protein_coding;locus_tag=NBT03_gp064;old_locus_tag=MPXV-M5312_HM12_Rivers-068 +NC_063383.1 RefSeq CDS 66756 68531 . - 0 ID=cds-YP_010377067.1;Parent=gene-NBT03_gp064;Dbxref=GenBank:YP_010377067.1,GeneID:72551480;Name=OPG085;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp070%3B proteinase%3B Metalloprotease%3B similar to VACV-WR G1L and VACV-Cop G1L;gbkey=CDS;gene=OPG085;locus_tag=NBT03_gp064;product=Metalloendopeptidase;protein_id=YP_010377067.1 +NC_063383.1 RefSeq gene 68528 68863 . - . ID=gene-NBT03_gp065;Dbxref=GeneID:72551481;Name=OPG086;gbkey=Gene;gene=OPG086;gene_biotype=protein_coding;locus_tag=NBT03_gp065;old_locus_tag=MPXV-M5312_HM12_Rivers-069 +NC_063383.1 RefSeq CDS 68528 68863 . - 0 ID=cds-YP_010377068.1;Parent=gene-NBT03_gp065;Dbxref=GenBank:YP_010377068.1,GeneID:72551481;Name=OPG086;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp071%3B Entry/fusion complex component%3B similar to VACV-WR G2L and VACV-Cop G3L;gbkey=CDS;gene=OPG086;locus_tag=NBT03_gp065;product=Entry/fusion complex component;protein_id=YP_010377068.1 +NC_063383.1 RefSeq gene 68857 69519 . + . ID=gene-NBT03_gp066;Dbxref=GeneID:72551482;Name=OPG087;gbkey=Gene;gene=OPG087;gene_biotype=protein_coding;locus_tag=NBT03_gp066;old_locus_tag=MPXV-M5312_HM12_Rivers-070 +NC_063383.1 RefSeq CDS 68857 69519 . + 0 ID=cds-YP_010377069.1;Parent=gene-NBT03_gp066;Dbxref=GenBank:YP_010377069.1,GeneID:72551482;Name=OPG087;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp072%3B VLTF (late transcription elongation factor)%3B similar to VACV-WR G3R and VACV-Cop G2R;gbkey=CDS;gene=OPG087;locus_tag=NBT03_gp066;product=Late transcription elongation factor;protein_id=YP_010377069.1 +NC_063383.1 RefSeq gene 69489 69863 . - . ID=gene-NBT03_gp067;Dbxref=GeneID:72551483;Name=OPG088;gbkey=Gene;gene=OPG088;gene_biotype=protein_coding;locus_tag=NBT03_gp067;old_locus_tag=MPXV-M5312_HM12_Rivers-071 +NC_063383.1 RefSeq CDS 69489 69863 . - 0 ID=cds-YP_010377070.1;Parent=gene-NBT03_gp067;Dbxref=GenBank:YP_010377070.1,GeneID:72551483;Name=OPG088;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp073%3B virion-associated glutaredoxin%3B Glutaredoxin-like protein%3B similar to VACV-WR G4L and VACV-Cop G4L;gbkey=CDS;gene=OPG088;locus_tag=NBT03_gp067;product=Glutaredoxin-2;protein_id=YP_010377070.1 +NC_063383.1 RefSeq gene 69866 71170 . + . ID=gene-NBT03_gp068;Dbxref=GeneID:72551484;Name=OPG089;gbkey=Gene;gene=OPG089;gene_biotype=protein_coding;locus_tag=NBT03_gp068;old_locus_tag=MPXV-M5312_HM12_Rivers-072 +NC_063383.1 RefSeq CDS 69866 71170 . + 0 ID=cds-YP_010377071.1;Parent=gene-NBT03_gp068;Dbxref=GenBank:YP_010377071.1,GeneID:72551484;Name=OPG089;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp074%3B FEN1-like nuclease%3B similar to VACV-WR G5R and VACV-Cop G5R;gbkey=CDS;gene=OPG089;locus_tag=NBT03_gp068;product=FEN1-like nuclease;protein_id=YP_010377071.1 +NC_063383.1 RefSeq gene 71179 71370 . + . ID=gene-NBT03_gp069;Dbxref=GeneID:72551485;Name=OPG090;gbkey=Gene;gene=OPG090;gene_biotype=protein_coding;locus_tag=NBT03_gp069;old_locus_tag=MPXV-M5312_HM12_Rivers-073 +NC_063383.1 RefSeq CDS 71179 71370 . + 0 ID=cds-YP_010377072.1;Parent=gene-NBT03_gp069;Dbxref=GenBank:YP_010377072.1,GeneID:72551485;Name=OPG090;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp075%3B RNA polymerase subunit%2C 7 kDa subunit (RPO7)%3B similar to VACV-WR G6R and VACV-Cop G5.5R;gbkey=CDS;gene=OPG090;locus_tag=NBT03_gp069;product=DNA-directed RNA polymerase 7 kDa subunit;protein_id=YP_010377072.1 +NC_063383.1 RefSeq gene 71370 71867 . + . ID=gene-NBT03_gp070;Dbxref=GeneID:72551486;Name=OPG091;gbkey=Gene;gene=OPG091;gene_biotype=protein_coding;locus_tag=NBT03_gp070;old_locus_tag=MPXV-M5312_HM12_Rivers-074 +NC_063383.1 RefSeq CDS 71370 71867 . + 0 ID=cds-YP_010377073.1;Parent=gene-NBT03_gp070;Dbxref=GenBank:YP_010377073.1,GeneID:72551486;Name=OPG091;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp076%3B NLPc/P60 superfamily protein%3B similar to VACV-WR G7R and VACV-Cop G6R;gbkey=CDS;gene=OPG091;locus_tag=NBT03_gp070;product=Nlpc/p60 superfamily protein;protein_id=YP_010377073.1 +NC_063383.1 RefSeq gene 71832 72947 . - . ID=gene-NBT03_gp071;Dbxref=GeneID:72551487;Name=OPG092;gbkey=Gene;gene=OPG092;gene_biotype=protein_coding;locus_tag=NBT03_gp071;old_locus_tag=MPXV-M5312_HM12_Rivers-075 +NC_063383.1 RefSeq CDS 71832 72947 . - 0 ID=cds-YP_010377074.1;Parent=gene-NBT03_gp071;Dbxref=GenBank:YP_010377074.1,GeneID:72551487;Name=OPG092;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp077%3B virion protein%3B Virion phosphoprotein%2C early morphogenesis%3B similar to VACV-WR G8L and VACV-Cop G7L;gbkey=CDS;gene=OPG092;locus_tag=NBT03_gp071;product=Assembly protein G7;protein_id=YP_010377074.1 +NC_063383.1 RefSeq gene 72978 73760 . + . ID=gene-NBT03_gp072;Dbxref=GeneID:72551488;Name=OPG093;gbkey=Gene;gene=OPG093;gene_biotype=protein_coding;locus_tag=NBT03_gp072;old_locus_tag=MPXV-M5312_HM12_Rivers-076 +NC_063383.1 RefSeq CDS 72978 73760 . + 0 ID=cds-YP_010377075.1;Parent=gene-NBT03_gp072;Dbxref=GenBank:YP_010377075.1,GeneID:72551488;Name=OPG093;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp078%3B late gene transcription factor%2C VLTF-1%3B similar to VACV-WR G9R and VACV-Cop G8R;gbkey=CDS;gene=OPG093;locus_tag=NBT03_gp072;product=Late transcription factor VLTF-1;protein_id=YP_010377075.1 +NC_063383.1 RefSeq gene 73780 74802 . + . ID=gene-NBT03_gp073;Dbxref=GeneID:72551489;Name=OPG094;gbkey=Gene;gene=OPG094;gene_biotype=protein_coding;locus_tag=NBT03_gp073;old_locus_tag=MPXV-M5312_HM12_Rivers-077 +NC_063383.1 RefSeq CDS 73780 74802 . + 0 ID=cds-YP_010377076.1;Parent=gene-NBT03_gp073;Dbxref=GenBank:YP_010377076.1,GeneID:72551489;Name=OPG094;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp079%3B myristylated protein%3B Entry/fusion complex component%2C myristylprotein%3B similar to VACV-WR G10R and VACV-Cop G9R;gbkey=CDS;gene=OPG094;locus_tag=NBT03_gp073;product=Myristylated protein;protein_id=YP_010377076.1 +NC_063383.1 RefSeq gene 74803 75555 . + . ID=gene-NBT03_gp074;Dbxref=GeneID:72551490;Name=OPG095;gbkey=Gene;gene=OPG095;gene_biotype=protein_coding;locus_tag=NBT03_gp074;old_locus_tag=MPXV-M5312_HM12_Rivers-078 +NC_063383.1 RefSeq CDS 74803 75555 . + 0 ID=cds-YP_010377077.1;Parent=gene-NBT03_gp074;Dbxref=GenBank:YP_010377077.1,GeneID:72551490;Name=OPG095;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp080%3B myristylated IMV surface membrane protein%3B similar to VACV-WR M1R and VACV-Cop L1R;gbkey=CDS;gene=OPG095;locus_tag=NBT03_gp074;product=IMV membrane protein L1R;protein_id=YP_010377077.1 +NC_063383.1 RefSeq gene 75587 75865 . + . ID=gene-NBT03_gp075;Dbxref=GeneID:72551491;Name=OPG096;gbkey=Gene;gene=OPG096;gene_biotype=protein_coding;locus_tag=NBT03_gp075;old_locus_tag=MPXV-M5312_HM12_Rivers-079 +NC_063383.1 RefSeq CDS 75587 75865 . + 0 ID=cds-YP_010377078.1;Parent=gene-NBT03_gp075;Dbxref=GenBank:YP_010377078.1,GeneID:72551491;Name=OPG096;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp081%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR M2R and VACV-Cop L2R;gbkey=CDS;gene=OPG096;locus_tag=NBT03_gp075;product=Crescent membrane and immature virion formation protein;protein_id=YP_010377078.1 +NC_063383.1 RefSeq gene 75841 76875 . - . ID=gene-NBT03_gp076;Dbxref=GeneID:72551492;Name=OPG097;gbkey=Gene;gene=OPG097;gene_biotype=protein_coding;locus_tag=NBT03_gp076;old_locus_tag=MPXV-M5312_HM12_Rivers-080 +NC_063383.1 RefSeq CDS 75841 76875 . - 0 ID=cds-YP_010377079.1;Parent=gene-NBT03_gp076;Dbxref=GenBank:YP_010377079.1,GeneID:72551492;Name=OPG097;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp082%3B Internal virion protein%3B similar to VACV-WR M3L and VACV-Cop L3L;gbkey=CDS;gene=OPG097;locus_tag=NBT03_gp076;product=Internal virion L3/FP4 protein;protein_id=YP_010377079.1 +NC_063383.1 RefSeq gene 76900 77655 . + . ID=gene-NBT03_gp077;Dbxref=GeneID:72551493;Name=OPG098;gbkey=Gene;gene=OPG098;gene_biotype=protein_coding;locus_tag=NBT03_gp077;old_locus_tag=MPXV-M5312_HM12_Rivers-081 +NC_063383.1 RefSeq CDS 76900 77655 . + 0 ID=cds-YP_010377080.1;Parent=gene-NBT03_gp077;Dbxref=GenBank:YP_010377080.1,GeneID:72551493;Name=OPG098;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp083%3B virion core protein vp8%3B stimulation of I8R helicase activity%3B ss/dsDNA binding protein (VP8)%3B similar to VACV-WR M4R and VACV-Cop L4R;gbkey=CDS;gene=OPG098;locus_tag=NBT03_gp077;product=Nucleic acid binding protein VP8/L4R;protein_id=YP_010377080.1 +NC_063383.1 RefSeq gene 77665 78051 . + . ID=gene-NBT03_gp078;Dbxref=GeneID:72551494;Name=OPG099;gbkey=Gene;gene=OPG099;gene_biotype=protein_coding;locus_tag=NBT03_gp078;old_locus_tag=MPXV-M5312_HM12_Rivers-082 +NC_063383.1 RefSeq CDS 77665 78051 . + 0 ID=cds-YP_010377081.1;Parent=gene-NBT03_gp078;Dbxref=GenBank:YP_010377081.1,GeneID:72551494;Name=OPG099;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp084%3B Entry and Fusion IMV protein%3B similar to VACV-WR M5R and VACV-Cop L5R;gbkey=CDS;gene=OPG099;locus_tag=NBT03_gp078;product=Membrane protein CL5;protein_id=YP_010377081.1 +NC_063383.1 RefSeq gene 78008 78466 . + . ID=gene-NBT03_gp079;Dbxref=GeneID:72551495;Name=OPG100;gbkey=Gene;gene=OPG100;gene_biotype=protein_coding;locus_tag=NBT03_gp079;old_locus_tag=MPXV-M5312_HM12_Rivers-083 +NC_063383.1 RefSeq CDS 78008 78466 . + 0 ID=cds-YP_010377082.1;Parent=gene-NBT03_gp079;Dbxref=GenBank:YP_010377082.1,GeneID:72551495;Name=OPG100;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp085%3B Virion morph%3B similar to VACV-WR L1R and VACV-Cop J1R;gbkey=CDS;gene=OPG100;locus_tag=NBT03_gp079;product=IMV membrane protein J1;protein_id=YP_010377082.1 +NC_063383.1 RefSeq gene 78486 79019 . + . ID=gene-NBT03_gp080;Dbxref=GeneID:72551496;Name=OPG101;gbkey=Gene;gene=OPG101;gene_biotype=protein_coding;locus_tag=NBT03_gp080;old_locus_tag=MPXV-M5312_HM12_Rivers-084 +NC_063383.1 RefSeq CDS 78486 79019 . + 0 ID=cds-YP_010377083.1;Parent=gene-NBT03_gp080;Dbxref=GenBank:YP_010377083.1,GeneID:72551496;Name=OPG101;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp086%3B thymidine kinase%3B similar to VACV-WR L2R and VACV-Cop J2R;gbkey=CDS;gene=OPG101;locus_tag=NBT03_gp080;product=Thymidine kinase;protein_id=YP_010377083.1 +NC_063383.1 RefSeq gene 79085 80086 . + . ID=gene-NBT03_gp081;Dbxref=GeneID:72551497;Name=OPG102;gbkey=Gene;gene=OPG102;gene_biotype=protein_coding;locus_tag=NBT03_gp081;old_locus_tag=MPXV-M5312_HM12_Rivers-085 +NC_063383.1 RefSeq CDS 79085 80086 . + 0 ID=cds-YP_010377084.1;Parent=gene-NBT03_gp081;Dbxref=GenBank:YP_010377084.1,GeneID:72551497;Name=OPG102;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp087%3B poly-A polymerase%2C stimulatory subunit%2C simultaneously cap-specific mRNA (nucleoside-O2'-)-methyltransferase%3B Poly (A) polymerase small subunit (VP39)%3B similar to VACV-WR L3R and VACV-Cop J3R;gbkey=CDS;gene=OPG102;locus_tag=NBT03_gp081;product=Cap-specific mRNA;protein_id=YP_010377084.1 +NC_063383.1 RefSeq gene 80001 80558 . + . ID=gene-NBT03_gp082;Dbxref=GeneID:72551498;Name=OPG103;gbkey=Gene;gene=OPG103;gene_biotype=protein_coding;locus_tag=NBT03_gp082;old_locus_tag=MPXV-M5312_HM12_Rivers-086 +NC_063383.1 RefSeq CDS 80001 80558 . + 0 ID=cds-YP_010377085.1;Parent=gene-NBT03_gp082;Dbxref=GenBank:YP_010377085.1,GeneID:72551498;Name=OPG103;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp088%3B RNA polymerase%2C 22 kDa subunit (RPO22)%3B similar to VACV-WR L4R and VACV-Cop J4R;gbkey=CDS;gene=OPG103;locus_tag=NBT03_gp082;product=DNA-directed RNA polymerase subunit;protein_id=YP_010377085.1 +NC_063383.1 RefSeq gene 80618 81019 . - . ID=gene-NBT03_gp083;Dbxref=GeneID:72551499;Name=OPG104;gbkey=Gene;gene=OPG104;gene_biotype=protein_coding;locus_tag=NBT03_gp083;old_locus_tag=MPXV-M5312_HM12_Rivers-087 +NC_063383.1 RefSeq CDS 80618 81019 . - 0 ID=cds-YP_010377086.1;Parent=gene-NBT03_gp083;Dbxref=GenBank:YP_010377086.1,GeneID:72551499;Name=OPG104;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp089%3B essential for virus multiplication%3B IMV membrane protein%3B similar to VACV-WR L5L and VACV-Cop J5L;gbkey=CDS;gene=OPG104;locus_tag=NBT03_gp083;product=Myristylated protein;protein_id=YP_010377086.1 +NC_063383.1 RefSeq gene 81126 84986 . + . ID=gene-NBT03_gp084;Dbxref=GeneID:72551500;Name=OPG105;gbkey=Gene;gene=OPG105;gene_biotype=protein_coding;locus_tag=NBT03_gp084;old_locus_tag=MPXV-M5312_HM12_Rivers-088 +NC_063383.1 RefSeq CDS 81126 84986 . + 0 ID=cds-YP_010377087.1;Parent=gene-NBT03_gp084;Dbxref=GenBank:YP_010377087.1,GeneID:72551500;Name=OPG105;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp090%3B RNA polymerase%2C 147 kDa subunit (RPO147)%3B similar to VACV-WR L6R and VACV-Cop J6R;gbkey=CDS;gene=OPG105;locus_tag=NBT03_gp084;product=DNA-dependent RNA polymerase subunit rpo147;protein_id=YP_010377087.1 +NC_063383.1 RefSeq gene 84983 85498 . - . ID=gene-NBT03_gp085;Dbxref=GeneID:72551501;Name=OPG106;gbkey=Gene;gene=OPG106;gene_biotype=protein_coding;locus_tag=NBT03_gp085;old_locus_tag=MPXV-M5312_HM12_Rivers-089 +NC_063383.1 RefSeq CDS 84983 85498 . - 0 ID=cds-YP_010377088.1;Parent=gene-NBT03_gp085;Dbxref=GenBank:YP_010377088.1,GeneID:72551501;Name=OPG106;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp091%3B tyrosine%3B Tyr/Ser phosphatase%2C IFN-gamma inhibitor%3B similar to VACV-WR H1L and VACV-Cop H1L;gbkey=CDS;gene=OPG106;locus_tag=NBT03_gp085;product=Tyr/ser protein phosphatase;protein_id=YP_010377088.1 +NC_063383.1 RefSeq gene 85512 86081 . + . ID=gene-NBT03_gp086;Dbxref=GeneID:72551502;Name=OPG107;gbkey=Gene;gene=OPG107;gene_biotype=protein_coding;locus_tag=NBT03_gp086;old_locus_tag=MPXV-M5312_HM12_Rivers-090 +NC_063383.1 RefSeq CDS 85512 86081 . + 0 ID=cds-YP_010377089.1;Parent=gene-NBT03_gp086;Dbxref=GenBank:YP_010377089.1,GeneID:72551502;Name=OPG107;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp092%3B IMV membrane protein%3B similar to VACV-WR H2R and VACV-Cop H2R;gbkey=CDS;gene=OPG107;locus_tag=NBT03_gp086;product=Entry-fusion complex essential component;protein_id=YP_010377089.1 +NC_063383.1 RefSeq gene 86085 87059 . - . ID=gene-NBT03_gp087;Dbxref=GeneID:72551503;Name=OPG108;gbkey=Gene;gene=OPG108;gene_biotype=protein_coding;locus_tag=NBT03_gp087;old_locus_tag=MPXV-M5312_HM12_Rivers-091 +NC_063383.1 RefSeq CDS 86085 87059 . - 0 ID=cds-YP_010377090.1;Parent=gene-NBT03_gp087;Dbxref=GenBank:YP_010377090.1,GeneID:72551503;Name=OPG108;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp093%3B IMV surface membrane protein%3B IMV heparin binding surface protein%3B similar to VACV-WR H3L and VACV-Cop H3L;gbkey=CDS;gene=OPG108;locus_tag=NBT03_gp087;product=IMV heparin binding surface protein;protein_id=YP_010377090.1 +NC_063383.1 RefSeq gene 87060 89447 . - . ID=gene-NBT03_gp088;Dbxref=GeneID:72551504;Name=OPG109;gbkey=Gene;gene=OPG109;gene_biotype=protein_coding;locus_tag=NBT03_gp088;old_locus_tag=MPXV-M5312_HM12_Rivers-092 +NC_063383.1 RefSeq CDS 87060 89447 . - 0 ID=cds-YP_010377091.1;Parent=gene-NBT03_gp088;Dbxref=GenBank:YP_010377091.1,GeneID:72551504;Name=OPG109;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp094%3B virion core RNA polymerase-associated protein%2C RAP94%3B similar to VACV-WR H4L and VACV-Cop H4L;gbkey=CDS;gene=OPG109;locus_tag=NBT03_gp088;product=RNA polymerase-associated transcription-specificity factor RAP94;protein_id=YP_010377091.1 +NC_063383.1 RefSeq gene 89632 90264 . + . ID=gene-NBT03_gp089;Dbxref=GeneID:72551505;Name=OPG110;gbkey=Gene;gene=OPG110;gene_biotype=protein_coding;locus_tag=NBT03_gp089;old_locus_tag=MPXV-M5312_HM12_Rivers-093 +NC_063383.1 RefSeq CDS 89632 90264 . + 0 ID=cds-YP_010377092.1;Parent=gene-NBT03_gp089;Dbxref=GenBank:YP_010377092.1,GeneID:72551505;Name=OPG110;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp095%3B virosome-associated late gene transcription factor%2C VLTF-4%3B Ca2+-binding motif%3B similar to VACV-WR H5R and VACV-Cop H5R;gbkey=CDS;gene=OPG110;locus_tag=NBT03_gp089;product=Late transcription factor VLTF-4 (1);protein_id=YP_010377092.1 +NC_063383.1 RefSeq gene 90265 91209 . + . ID=gene-NBT03_gp090;Dbxref=GeneID:72551506;Name=OPG111;gbkey=Gene;gene=OPG111;gene_biotype=protein_coding;locus_tag=NBT03_gp090;old_locus_tag=MPXV-M5312_HM12_Rivers-094 +NC_063383.1 RefSeq CDS 90265 91209 . + 0 ID=cds-YP_010377093.1;Parent=gene-NBT03_gp090;Dbxref=GenBank:YP_010377093.1,GeneID:72551506;Name=OPG111;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp096%3B DNA topoisomerase type I%3B similar to VACV-WR H6R and VACV-Cop H6R;gbkey=CDS;gene=OPG111;locus_tag=NBT03_gp090;product=DNA topoisomerase type I;protein_id=YP_010377093.1 +NC_063383.1 RefSeq gene 91247 91687 . + . ID=gene-NBT03_gp091;Dbxref=GeneID:72551507;Name=OPG112;gbkey=Gene;gene=OPG112;gene_biotype=protein_coding;locus_tag=NBT03_gp091;old_locus_tag=MPXV-M5312_HM12_Rivers-095 +NC_063383.1 RefSeq CDS 91247 91687 . + 0 ID=cds-YP_010377094.1;Parent=gene-NBT03_gp091;Dbxref=GenBank:YP_010377094.1,GeneID:72551507;Name=OPG112;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp097%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR H7R and VACV-Cop H7R;gbkey=CDS;gene=OPG112;locus_tag=NBT03_gp091;product=Late protein H7;protein_id=YP_010377094.1 +NC_063383.1 RefSeq gene 91731 94268 . + . ID=gene-NBT03_gp092;Dbxref=GeneID:72551508;Name=OPG113;gbkey=Gene;gene=OPG113;gene_biotype=protein_coding;locus_tag=NBT03_gp092;old_locus_tag=MPXV-M5312_HM12_Rivers-096 +NC_063383.1 RefSeq CDS 91731 94268 . + 0 ID=cds-YP_010377095.1;Parent=gene-NBT03_gp092;Dbxref=GenBank:YP_010377095.1,GeneID:72551508;Name=OPG113;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp098%3B mRNA capping enzyme%2C large subunit%3B RNA 5' triphosphatase and RNA guanylyl transferase activities%3B similar to VACV-WR E1R and VACV-Cop D1R;gbkey=CDS;gene=OPG113;locus_tag=NBT03_gp092;product=mRNA capping enzyme large subunit;protein_id=YP_010377095.1 +NC_063383.1 RefSeq gene 94227 94667 . - . ID=gene-NBT03_gp093;Dbxref=GeneID:72551509;Name=OPG114;gbkey=Gene;gene=OPG114;gene_biotype=protein_coding;locus_tag=NBT03_gp093;old_locus_tag=MPXV-M5312_HM12_Rivers-097 +NC_063383.1 RefSeq CDS 94227 94667 . - 0 ID=cds-YP_010377096.1;Parent=gene-NBT03_gp093;Dbxref=GenBank:YP_010377096.1,GeneID:72551509;Name=OPG114;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp099%3B virion core protein%3B similar to VACV-WR E2L and VACV-Cop D2L;gbkey=CDS;gene=OPG114;locus_tag=NBT03_gp093;product=Virion protein D2;protein_id=YP_010377096.1 +NC_063383.1 RefSeq gene 94660 95361 . + . ID=gene-NBT03_gp094;Dbxref=GeneID:72551510;Name=OPG115;gbkey=Gene;gene=OPG115;gene_biotype=protein_coding;locus_tag=NBT03_gp094;old_locus_tag=MPXV-M5312_HM12_Rivers-098 +NC_063383.1 RefSeq CDS 94660 95361 . + 0 ID=cds-YP_010377097.1;Parent=gene-NBT03_gp094;Dbxref=GenBank:YP_010377097.1,GeneID:72551510;Name=OPG115;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp100%3B virion core protein%3B similar to VACV-WR E3R and VACV-Cop D3R;gbkey=CDS;gene=OPG115;locus_tag=NBT03_gp094;product=Virion core protein D3;protein_id=YP_010377097.1 +NC_063383.1 RefSeq gene 95361 96017 . + . ID=gene-NBT03_gp095;Dbxref=GeneID:72551511;Name=OPG116;gbkey=Gene;gene=OPG116;gene_biotype=protein_coding;locus_tag=NBT03_gp095;old_locus_tag=MPXV-M5312_HM12_Rivers-099 +NC_063383.1 RefSeq CDS 95361 96017 . + 0 ID=cds-YP_010377098.1;Parent=gene-NBT03_gp095;Dbxref=GenBank:YP_010377098.1,GeneID:72551511;Name=OPG116;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp101%3B uracil DNA glycosylase%3B DNA polymerase processivity factor%3B similar to VACV-WR E4R and VACV-Cop D4R;gbkey=CDS;gene=OPG116;locus_tag=NBT03_gp095;product=Uracil DNA glycosylase superfamily;protein_id=YP_010377098.1 +NC_063383.1 RefSeq gene 96049 98406 . + . ID=gene-NBT03_gp096;Dbxref=GeneID:72551512;Name=OPG117;gbkey=Gene;gene=OPG117;gene_biotype=protein_coding;locus_tag=NBT03_gp096;old_locus_tag=MPXV-M5312_HM12_Rivers-100 +NC_063383.1 RefSeq CDS 96049 98406 . + 0 ID=cds-YP_010377099.1;Parent=gene-NBT03_gp096;Dbxref=GenBank:YP_010377099.1,GeneID:72551512;Name=OPG117;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp102%3B nucleic acid-independent nucleoside triphosphatase%3B NTPase%2C DNA primase%3B similar to VACV-WR E5R and VACV-Cop D5R;gbkey=CDS;gene=OPG117;locus_tag=NBT03_gp096;product=NTPase (1);protein_id=YP_010377099.1 +NC_063383.1 RefSeq gene 98446 100359 . + . ID=gene-NBT03_gp097;Dbxref=GeneID:72551513;Name=OPG118;gbkey=Gene;gene=OPG118;gene_biotype=protein_coding;locus_tag=NBT03_gp097;old_locus_tag=MPXV-M5312_HM12_Rivers-101 +NC_063383.1 RefSeq CDS 98446 100359 . + 0 ID=cds-YP_010377100.1;Parent=gene-NBT03_gp097;Dbxref=GenBank:YP_010377100.1,GeneID:72551513;Name=OPG118;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp103%3B early transcription factor%2C small subunit%2C VETF-s%3B Morphogenesis%3B similar to VACV-WR E6R and VACV-Cop D6R;gbkey=CDS;gene=OPG118;locus_tag=NBT03_gp097;product=Early transcription factor 70 kDa subunit;protein_id=YP_010377100.1 +NC_063383.1 RefSeq gene 100386 100871 . + . ID=gene-NBT03_gp098;Dbxref=GeneID:72551514;Name=OPG119;gbkey=Gene;gene=OPG119;gene_biotype=protein_coding;locus_tag=NBT03_gp098;old_locus_tag=MPXV-M5312_HM12_Rivers-102 +NC_063383.1 RefSeq CDS 100386 100871 . + 0 ID=cds-YP_010377101.1;Parent=gene-NBT03_gp098;Dbxref=GenBank:YP_010377101.1,GeneID:72551514;Name=OPG119;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp104%3B RNA polymerase%2C 18 kDa subunit (RPO18)%3B similar to VACV-WR E7R and VACV-Cop D7R;gbkey=CDS;gene=OPG119;locus_tag=NBT03_gp098;product=RNA polymerase subunit RPO18;protein_id=YP_010377101.1 +NC_063383.1 RefSeq gene 100834 101748 . - . ID=gene-NBT03_gp099;Dbxref=GeneID:72551515;Name=OPG120;gbkey=Gene;gene=OPG120;gene_biotype=protein_coding;locus_tag=NBT03_gp099;old_locus_tag=MPXV-M5312_HM12_Rivers-103 +NC_063383.1 RefSeq CDS 100834 101748 . - 0 ID=cds-YP_010377102.1;Parent=gene-NBT03_gp099;Dbxref=GenBank:YP_010377102.1,GeneID:72551515;Name=OPG120;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp105%3B IMV surface membrane 32 kDa protein%3B binding to cell surface chondroitin sulfate%3B IMV adsorption to cell surface%3B GAG-binding IMV membrane protein%3B similar to VACV-WR E8L and VACV-Cop D8L;gbkey=CDS;gene=OPG120;locus_tag=NBT03_gp099;product=Carbonic anhydrase;protein_id=YP_010377102.1 +NC_063383.1 RefSeq gene 101790 102431 . + . ID=gene-NBT03_gp100;Dbxref=GeneID:72551516;Name=OPG121;gbkey=Gene;gene=OPG121;gene_biotype=protein_coding;locus_tag=NBT03_gp100;old_locus_tag=MPXV-M5312_HM12_Rivers-104 +NC_063383.1 RefSeq CDS 101790 102431 . + 0 ID=cds-YP_010377103.1;Parent=gene-NBT03_gp100;Dbxref=GenBank:YP_010377103.1,GeneID:72551516;Name=OPG121;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp106%3B Mut-like%3B mRNA decapping enzyme%3B similar to VACV-WR E9R and VACV-Cop D9R;gbkey=CDS;gene=OPG121;locus_tag=NBT03_gp100;product=NUDIX domain protein;protein_id=YP_010377103.1 +NC_063383.1 RefSeq gene 102428 103174 . + . ID=gene-NBT03_gp101;Dbxref=GeneID:72551517;Name=OPG122;gbkey=Gene;gene=OPG122;gene_biotype=protein_coding;locus_tag=NBT03_gp101;old_locus_tag=MPXV-M5312_HM12_Rivers-105 +NC_063383.1 RefSeq CDS 102428 103174 . + 0 ID=cds-YP_010377104.1;Parent=gene-NBT03_gp101;Dbxref=GenBank:YP_010377104.1,GeneID:72551517;Name=OPG122;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp107%3B down regulation of gene expression%3B Mut-like%3B mRNA decapping enzyme%3B similar to VACV-WR E10R and VACV-Cop D10R;gbkey=CDS;gene=OPG122;locus_tag=NBT03_gp101;product=MutT motif protein;protein_id=YP_010377104.1 +NC_063383.1 RefSeq gene 103175 105070 . - . ID=gene-NBT03_gp102;Dbxref=GeneID:72551518;Name=OPG123;gbkey=Gene;gene=OPG123;gene_biotype=protein_coding;locus_tag=NBT03_gp102;old_locus_tag=MPXV-M5312_HM12_Rivers-106 +NC_063383.1 RefSeq CDS 103175 105070 . - 0 ID=cds-YP_010377105.1;Parent=gene-NBT03_gp102;Dbxref=GenBank:YP_010377105.1,GeneID:72551518;Name=OPG123;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp108%3B nucleoside triphosphate phosphohydrolase I%2C NPH I%3B DNA-dependent ATPase%3B early gene transcription termination factor%3B similar to VACV-WR E11L and VACV-Cop D11L;gbkey=CDS;gene=OPG123;locus_tag=NBT03_gp102;product=Nucleoside triphosphatase I;protein_id=YP_010377105.1 +NC_063383.1 RefSeq gene 105105 105968 . - . ID=gene-NBT03_gp103;Dbxref=GeneID:72551519;Name=OPG124;gbkey=Gene;gene=OPG124;gene_biotype=protein_coding;locus_tag=NBT03_gp103;old_locus_tag=MPXV-M5312_HM12_Rivers-107 +NC_063383.1 RefSeq CDS 105105 105968 . - 0 ID=cds-YP_010377106.1;Parent=gene-NBT03_gp103;Dbxref=GenBank:YP_010377106.1,GeneID:72551519;Name=OPG124;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp109%3B mRNA capping enzyme small subunit%3B mRNA (guanine-N7-)-methyl-transferase%3B transcription initiation factor%3B similar to VACV-WR E12L and VACV-Cop D12L;gbkey=CDS;gene=OPG124;locus_tag=NBT03_gp103;product=mRNA capping enzyme small subunit;protein_id=YP_010377106.1 +NC_063383.1 RefSeq gene 105999 107654 . - . ID=gene-NBT03_gp104;Dbxref=GeneID:72551520;Name=OPG125;gbkey=Gene;gene=OPG125;gene_biotype=protein_coding;locus_tag=NBT03_gp104;old_locus_tag=MPXV-M5312_HM12_Rivers-108 +NC_063383.1 RefSeq CDS 105999 107654 . - 0 ID=cds-YP_010377107.1;Parent=gene-NBT03_gp104;Dbxref=GenBank:YP_010377107.1,GeneID:72551520;Name=OPG125;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp110%3B protein needed for the formation of immature IMV surface membrane%3B Trimeric virion coat protein (rifampicin res)%3B similar to VACV-WR E13L and VACV-Cop D13L;gbkey=CDS;gene=OPG125;locus_tag=NBT03_gp104;product=Rifampicin resistance protein;protein_id=YP_010377107.1 +NC_063383.1 RefSeq gene 107678 108130 . - . ID=gene-NBT03_gp105;Dbxref=GeneID:72551521;Name=OPG126;gbkey=Gene;gene=OPG126;gene_biotype=protein_coding;locus_tag=NBT03_gp105;old_locus_tag=MPXV-M5312_HM12_Rivers-109 +NC_063383.1 RefSeq CDS 107678 108130 . - 0 ID=cds-YP_010377108.1;Parent=gene-NBT03_gp105;Dbxref=GenBank:YP_010377108.1,GeneID:72551521;Name=OPG126;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp111%3B late gene transcription factor%2C VLTF-2%3B similar to VACV-WR A1L and VACV-Cop A1L;gbkey=CDS;gene=OPG126;locus_tag=NBT03_gp105;product=Late transcription factor VLTF-2 (2);protein_id=YP_010377108.1 +NC_063383.1 RefSeq gene 108151 108825 . - . ID=gene-NBT03_gp106;Dbxref=GeneID:72551522;Name=OPG127;gbkey=Gene;gene=OPG127;gene_biotype=protein_coding;locus_tag=NBT03_gp106;old_locus_tag=MPXV-M5312_HM12_Rivers-110 +NC_063383.1 RefSeq CDS 108151 108825 . - 0 ID=cds-YP_010377109.1;Parent=gene-NBT03_gp106;Dbxref=GenBank:YP_010377109.1,GeneID:72551522;Name=OPG127;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp112%3B late gene transcription factor%2C VLTF-3%3B zinc binding%3B similar to VACV-WR A2L and VACV-Cop A2L;gbkey=CDS;gene=OPG127;locus_tag=NBT03_gp106;product=Late transcription factor VLTF-3 (1);protein_id=YP_010377109.1 +NC_063383.1 RefSeq gene 108822 109055 . - . ID=gene-NBT03_gp107;Dbxref=GeneID:72551523;Name=OPG128;gbkey=Gene;gene=OPG128;gene_biotype=protein_coding;locus_tag=NBT03_gp107;old_locus_tag=MPXV-M5312_HM12_Rivers-111 +NC_063383.1 RefSeq CDS 108822 109055 . - 0 ID=cds-YP_010377110.1;Parent=gene-NBT03_gp107;Dbxref=GenBank:YP_010377110.1,GeneID:72551523;Name=OPG128;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp113%3B S-S bond formation pathway protein%3B similar to VACV-WR A3L and VACV-Cop A2.5L;gbkey=CDS;gene=OPG128;locus_tag=NBT03_gp107;product=S-S bond formation pathway protein;protein_id=YP_010377110.1 +NC_063383.1 RefSeq gene 109070 111004 . - . ID=gene-NBT03_gp108;Dbxref=GeneID:72551524;Name=OPG129;gbkey=Gene;gene=OPG129;gene_biotype=protein_coding;locus_tag=NBT03_gp108;old_locus_tag=MPXV-M5312_HM12_Rivers-112 +NC_063383.1 RefSeq CDS 109070 111004 . - 0 ID=cds-YP_010377111.1;Parent=gene-NBT03_gp108;Dbxref=GenBank:YP_010377111.1,GeneID:72551524;Name=OPG129;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp114%3B major virion core protein p4b%3B P4b precursor%3B similar to VACV-WR A4L and VACV-Cop A3L;gbkey=CDS;gene=OPG129;locus_tag=NBT03_gp108;product=Virion core protein P4b;protein_id=YP_010377111.1 +NC_063383.1 RefSeq gene 111057 111902 . - . ID=gene-NBT03_gp109;Dbxref=GeneID:72551525;Name=OPG130;gbkey=Gene;gene=OPG130;gene_biotype=protein_coding;locus_tag=NBT03_gp109;old_locus_tag=MPXV-M5312_HM12_Rivers-113 +NC_063383.1 RefSeq CDS 111057 111902 . - 0 ID=cds-YP_010377112.1;Parent=gene-NBT03_gp109;Dbxref=GenBank:YP_010377112.1,GeneID:72551525;Name=OPG130;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp115%3B 39 kDa immunodominant virion core protein needed for the progression of IV to infectious IMV%3B 39kDa virion core protein%3B similar to VACV-WR A5L and VACV-Cop A4L;gbkey=CDS;gene=OPG130;locus_tag=NBT03_gp109;product=A5L protein-like;protein_id=YP_010377112.1 +NC_063383.1 RefSeq gene 111940 112425 . + . ID=gene-NBT03_gp110;Dbxref=GeneID:72551526;Name=OPG131;gbkey=Gene;gene=OPG131;gene_biotype=protein_coding;locus_tag=NBT03_gp110;old_locus_tag=MPXV-M5312_HM12_Rivers-114 +NC_063383.1 RefSeq CDS 111940 112425 . + 0 ID=cds-YP_010377113.1;Parent=gene-NBT03_gp110;Dbxref=GenBank:YP_010377113.1,GeneID:72551526;Name=OPG131;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp116%3B precursor of RNA polymerase 22 kDa and 21 kDa%3B RNA polymerase subunit (RPO19)%3B similar to VACV-WR A6R and VACV-Cop A5R;gbkey=CDS;gene=OPG131;locus_tag=NBT03_gp110;product=DNA-directed RNA polymerase 19 kDa subunit;protein_id=YP_010377113.1 +NC_063383.1 RefSeq gene 112422 113540 . - . ID=gene-NBT03_gp111;Dbxref=GeneID:72551527;Name=OPG132;gbkey=Gene;gene=OPG132;gene_biotype=protein_coding;locus_tag=NBT03_gp111;old_locus_tag=MPXV-M5312_HM12_Rivers-115 +NC_063383.1 RefSeq CDS 112422 113540 . - 0 ID=cds-YP_010377114.1;Parent=gene-NBT03_gp111;Dbxref=GenBank:YP_010377114.1,GeneID:72551527;Name=OPG132;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp117%3B Viral membrane assembly proteins (VMAP)%2C core protein%3B similar to VACV-WR A7L and VACV-Cop A6L;gbkey=CDS;gene=OPG132;locus_tag=NBT03_gp111;product=Virion morphogenesis protein;protein_id=YP_010377114.1 +NC_063383.1 RefSeq gene 113564 115696 . - . ID=gene-NBT03_gp112;Dbxref=GeneID:72551528;Name=OPG133;gbkey=Gene;gene=OPG133;gene_biotype=protein_coding;locus_tag=NBT03_gp112;old_locus_tag=MPXV-M5312_HM12_Rivers-116 +NC_063383.1 RefSeq CDS 113564 115696 . - 0 ID=cds-YP_010377115.1;Parent=gene-NBT03_gp112;Dbxref=GenBank:YP_010377115.1,GeneID:72551528;Name=OPG133;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp118%3B early transcription factor%2C large subunit%2C VETF-L%3B needed for morphogenesis of the virion core%3B similar to VACV-WR A8L and VACV-Cop A7L;gbkey=CDS;gene=OPG133;locus_tag=NBT03_gp112;product=Early transcription factor 82 kDa subunit;protein_id=YP_010377115.1 +NC_063383.1 RefSeq gene 115750 116628 . + . ID=gene-NBT03_gp113;Dbxref=GeneID:72551529;Name=OPG134;gbkey=Gene;gene=OPG134;gene_biotype=protein_coding;locus_tag=NBT03_gp113;old_locus_tag=MPXV-M5312_HM12_Rivers-117 +NC_063383.1 RefSeq CDS 115750 116628 . + 0 ID=cds-YP_010377116.1;Parent=gene-NBT03_gp113;Dbxref=GenBank:YP_010377116.1,GeneID:72551529;Name=OPG134;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp119%3B intermediate transcription factor%2C VITF-3 34kda subunit%2C 34 kDa%3B similar to VACV-WR A9R and VACV-Cop A8R;gbkey=CDS;gene=OPG134;locus_tag=NBT03_gp113;product=Intermediate transcription factor VITF-3 (1);protein_id=YP_010377116.1 +NC_063383.1 RefSeq gene 116609 116911 . - . ID=gene-NBT03_gp114;Dbxref=GeneID:72551530;Name=OPG135;gbkey=Gene;gene=OPG135;gene_biotype=protein_coding;locus_tag=NBT03_gp114;old_locus_tag=MPXV-M5312_HM12_Rivers-118 +NC_063383.1 RefSeq CDS 116609 116911 . - 0 ID=cds-YP_010377117.1;Parent=gene-NBT03_gp114;Dbxref=GenBank:YP_010377117.1,GeneID:72551530;Name=OPG135;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp120%3B Viral membrane associated%2C early morphogenesis protein%3B similar to VACV-WR A10L and VACV-Cop A9L;gbkey=CDS;gene=OPG135;locus_tag=NBT03_gp114;product=IMV membrane protein A9;protein_id=YP_010377117.1 +NC_063383.1 RefSeq gene 116912 119587 . - . ID=gene-NBT03_gp115;Dbxref=GeneID:72551531;Name=OPG136;gbkey=Gene;gene=OPG136;gene_biotype=protein_coding;locus_tag=NBT03_gp115;old_locus_tag=MPXV-M5312_HM12_Rivers-119 +NC_063383.1 RefSeq CDS 116912 119587 . - 0 ID=cds-YP_010377118.1;Parent=gene-NBT03_gp115;Dbxref=GenBank:YP_010377118.1,GeneID:72551531;Name=OPG136;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp121%3B major virion core protein p4a%3B P4a precursor%3B similar to VACV-WR A11L and VACV-Cop A10L;gbkey=CDS;gene=OPG136;locus_tag=NBT03_gp115;product=Virion core protein P4a;protein_id=YP_010377118.1 +NC_063383.1 RefSeq gene 119602 120558 . + . ID=gene-NBT03_gp116;Dbxref=GeneID:72551532;Name=OPG137;gbkey=Gene;gene=OPG137;gene_biotype=protein_coding;locus_tag=NBT03_gp116;old_locus_tag=MPXV-M5312_HM12_Rivers-120 +NC_063383.1 RefSeq CDS 119602 120558 . + 0 ID=cds-YP_010377119.1;Parent=gene-NBT03_gp116;Dbxref=GenBank:YP_010377119.1,GeneID:72551532;Name=OPG137;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp122%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR A12R and VACV-Cop A11R;gbkey=CDS;gene=OPG137;locus_tag=NBT03_gp116;product=Viral membrane formation protein;protein_id=YP_010377119.1 +NC_063383.1 RefSeq gene 120560 121132 . - . ID=gene-NBT03_gp117;Dbxref=GeneID:72551533;Name=OPG138;gbkey=Gene;gene=OPG138;gene_biotype=protein_coding;locus_tag=NBT03_gp117;old_locus_tag=MPXV-M5312_HM12_Rivers-121 +NC_063383.1 RefSeq CDS 120560 121132 . - 0 ID=cds-YP_010377120.1;Parent=gene-NBT03_gp117;Dbxref=GenBank:YP_010377120.1,GeneID:72551533;Name=OPG138;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp123%3B Virion core and cleavage processing protein%3B similar to VACV-WR A13L and VACV-Cop A12L;gbkey=CDS;gene=OPG138;locus_tag=NBT03_gp117;product=A12 protein;protein_id=YP_010377120.1 +NC_063383.1 RefSeq gene 121156 121368 . - . ID=gene-NBT03_gp118;Dbxref=GeneID:72551534;Name=OPG139;gbkey=Gene;gene=OPG139;gene_biotype=protein_coding;locus_tag=NBT03_gp118;old_locus_tag=MPXV-M5312_HM12_Rivers-122 +NC_063383.1 RefSeq CDS 121156 121368 . - 0 ID=cds-YP_010377121.1;Parent=gene-NBT03_gp118;Dbxref=GenBank:YP_010377121.1,GeneID:72551534;Name=OPG139;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp124%3B IMV inner and outer membrane protein%3B virion maturation%3B similar to VACV-WR A14L and VACV-Cop A13L;gbkey=CDS;gene=OPG139;locus_tag=NBT03_gp118;product=IMV membrane protein A13L;protein_id=YP_010377121.1 +NC_063383.1 RefSeq gene 121474 121746 . - . ID=gene-NBT03_gp119;Dbxref=GeneID:72551535;Name=OPG140;gbkey=Gene;gene=OPG140;gene_biotype=protein_coding;locus_tag=NBT03_gp119;old_locus_tag=MPXV-M5312_HM12_Rivers-123 +NC_063383.1 RefSeq CDS 121474 121746 . - 0 ID=cds-YP_010377122.1;Parent=gene-NBT03_gp119;Dbxref=GenBank:YP_010377122.1,GeneID:72551535;Name=OPG140;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp125%3B IMV inner membrane protein%3B Essential IMV membrane protein%3B similar to VACV-WR A15L and VACV-Cop A14L;gbkey=CDS;gene=OPG140;locus_tag=NBT03_gp119;product=IMV membrane protein A14;protein_id=YP_010377122.1 +NC_063383.1 RefSeq gene 121763 121924 . - . ID=gene-NBT03_gp120;Dbxref=GeneID:72551536;Name=OPG141;gbkey=Gene;gene=OPG141;gene_biotype=protein_coding;locus_tag=NBT03_gp120;old_locus_tag=MPXV-M5312_HM12_Rivers-124 +NC_063383.1 RefSeq CDS 121763 121924 . - 0 ID=cds-YP_010377123.1;Parent=gene-NBT03_gp120;Dbxref=GenBank:YP_010377123.1,GeneID:72551536;Name=OPG141;Note=Taxonomic breadth: chordopoxvirinae%3B Non-essential IMV membrane protein%3B similar to VACV-WR A15.5L and VACV-Cop A14.5L;gbkey=CDS;gene=OPG141;locus_tag=NBT03_gp120;product=DUF1029 domain protein;protein_id=YP_010377123.1 +NC_063383.1 RefSeq gene 121914 122198 . - . ID=gene-NBT03_gp121;Dbxref=GeneID:72551537;Name=OPG142;gbkey=Gene;gene=OPG142;gene_biotype=protein_coding;locus_tag=NBT03_gp121;old_locus_tag=MPXV-M5312_HM12_Rivers-125 +NC_063383.1 RefSeq CDS 121914 122198 . - 0 ID=cds-YP_010377124.1;Parent=gene-NBT03_gp121;Dbxref=GenBank:YP_010377124.1,GeneID:72551537;Name=OPG142;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp126%3B Core protein%3B similar to VACV-WR A16L and VACV-Cop A15L;gbkey=CDS;gene=OPG142;locus_tag=NBT03_gp121;product=Core protein A15;protein_id=YP_010377124.1 +NC_063383.1 RefSeq gene 122182 123315 . - . ID=gene-NBT03_gp122;Dbxref=GeneID:72551538;Name=OPG143;gbkey=Gene;gene=OPG143;gene_biotype=protein_coding;locus_tag=NBT03_gp122;old_locus_tag=MPXV-M5312_HM12_Rivers-126 +NC_063383.1 RefSeq CDS 122182 123315 . - 0 ID=cds-YP_010377125.1;Parent=gene-NBT03_gp122;Dbxref=GenBank:YP_010377125.1,GeneID:72551538;Name=OPG143;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp127%3B soluble myristylated protein%3B essential for entry/fusion%3B similar to VACV-WR A17L and VACV-Cop A16L;gbkey=CDS;gene=OPG143;locus_tag=NBT03_gp122;product=Myristylated protein;protein_id=YP_010377125.1 +NC_063383.1 RefSeq gene 123318 123932 . - . ID=gene-NBT03_gp123;Dbxref=GeneID:72551539;Name=OPG144;gbkey=Gene;gene=OPG144;gene_biotype=protein_coding;locus_tag=NBT03_gp123;old_locus_tag=MPXV-M5312_HM12_Rivers-127 +NC_063383.1 RefSeq CDS 123318 123932 . - 0 ID=cds-YP_010377126.1;Parent=gene-NBT03_gp123;Dbxref=GenBank:YP_010377126.1,GeneID:72551539;Name=OPG144;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp128%3B IMV surface membrane protein%3B early function in virion morphgenesis%3B similar to VACV-WR A18L and VACV-Cop A17L;gbkey=CDS;gene=OPG144;locus_tag=NBT03_gp123;product=IMV membrane protein P21;protein_id=YP_010377126.1 +NC_063383.1 RefSeq gene 123947 125425 . + . ID=gene-NBT03_gp124;Dbxref=GeneID:72551540;Name=OPG145;gbkey=Gene;gene=OPG145;gene_biotype=protein_coding;locus_tag=NBT03_gp124;old_locus_tag=MPXV-M5312_HM12_Rivers-128 +NC_063383.1 RefSeq CDS 123947 125425 . + 0 ID=cds-YP_010377127.1;Parent=gene-NBT03_gp124;Dbxref=GenBank:YP_010377127.1,GeneID:72551540;Name=OPG145;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp129%3B virion core associated DNA helicase%3B post-replicative negative transcription elongation factor%3B transcript release factor%3B similar to VACV-WR A19R and VACV-Cop A18R;gbkey=CDS;gene=OPG145;locus_tag=NBT03_gp124;product=DNA helicase;protein_id=YP_010377127.1 +NC_063383.1 RefSeq gene 125406 125639 . - . ID=gene-NBT03_gp125;Dbxref=GeneID:72551541;Name=OPG146;gbkey=Gene;gene=OPG146;gene_biotype=protein_coding;locus_tag=NBT03_gp125;old_locus_tag=MPXV-M5312_HM12_Rivers-129 +NC_063383.1 RefSeq CDS 125406 125639 . - 0 ID=cds-YP_010377128.1;Parent=gene-NBT03_gp125;Dbxref=GenBank:YP_010377128.1,GeneID:72551541;Name=OPG146;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp130%3B Zinc finger-like protein%3B similar to VACV-WR A20L and VACV-Cop A19L;gbkey=CDS;gene=OPG146;locus_tag=NBT03_gp125;product=Zinc finger-like protein (1);protein_id=YP_010377128.1 +NC_063383.1 RefSeq gene 125640 125987 . - . ID=gene-NBT03_gp126;Dbxref=GeneID:72551542;Name=OPG147;gbkey=Gene;gene=OPG147;gene_biotype=protein_coding;locus_tag=NBT03_gp126;old_locus_tag=MPXV-M5312_HM12_Rivers-130 +NC_063383.1 RefSeq CDS 125640 125987 . - 0 ID=cds-YP_010377129.1;Parent=gene-NBT03_gp126;Dbxref=GenBank:YP_010377129.1,GeneID:72551542;Name=OPG147;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp131%3B IMV membrane protein%2C entry/fusion complex component%3B similar to VACV-WR A21L and VACV-Cop A21L;gbkey=CDS;gene=OPG147;locus_tag=NBT03_gp126;product=IMV membrane protein A21;protein_id=YP_010377129.1 +NC_063383.1 RefSeq gene 125986 127266 . + . ID=gene-NBT03_gp127;Dbxref=GeneID:72551543;Name=OPG148;gbkey=Gene;gene=OPG148;gene_biotype=protein_coding;locus_tag=NBT03_gp127;old_locus_tag=MPXV-M5312_HM12_Rivers-131 +NC_063383.1 RefSeq CDS 125986 127266 . + 0 ID=cds-YP_010377130.1;Parent=gene-NBT03_gp127;Dbxref=GenBank:YP_010377130.1,GeneID:72551543;Name=OPG148;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp132%3B processivity factor for the viral DNA polymerase%2C VPF%3B similar to VACV-WR A22R and VACV-Cop A20R;gbkey=CDS;gene=OPG148;locus_tag=NBT03_gp127;product=DNA polymerase processivity factor;protein_id=YP_010377130.1 +NC_063383.1 RefSeq gene 127196 127759 . + . ID=gene-NBT03_gp128;Dbxref=GeneID:72551544;Name=OPG149;gbkey=Gene;gene=OPG149;gene_biotype=protein_coding;locus_tag=NBT03_gp128;old_locus_tag=MPXV-M5312_HM12_Rivers-132 +NC_063383.1 RefSeq CDS 127196 127759 . + 0 ID=cds-YP_010377131.1;Parent=gene-NBT03_gp128;Dbxref=GenBank:YP_010377131.1,GeneID:72551544;Name=OPG149;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp133%3B Holliday junction resolvase%3B similar to VACV-WR A23R and VACV-Cop A22R;gbkey=CDS;gene=OPG149;locus_tag=NBT03_gp128;product=Holliday junction resolvase;protein_id=YP_010377131.1 +NC_063383.1 RefSeq gene 127779 128927 . + . ID=gene-NBT03_gp129;Dbxref=GeneID:72551545;Name=OPG150;gbkey=Gene;gene=OPG150;gene_biotype=protein_coding;locus_tag=NBT03_gp129;old_locus_tag=MPXV-M5312_HM12_Rivers-133 +NC_063383.1 RefSeq CDS 127779 128927 . + 0 ID=cds-YP_010377132.1;Parent=gene-NBT03_gp129;Dbxref=GenBank:YP_010377132.1,GeneID:72551545;Name=OPG150;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp134%3B intermediate transcription factor%2C VITF-3%2C 45 kDa subunit%3B similar to VACV-WR A24R and VACV-Cop A23R;gbkey=CDS;gene=OPG150;locus_tag=NBT03_gp129;product=Intermediate transcription factor VITF-3 (2);protein_id=YP_010377132.1 +NC_063383.1 RefSeq gene 128924 132418 . + . ID=gene-NBT03_gp130;Dbxref=GeneID:72551546;Name=OPG151;gbkey=Gene;gene=OPG151;gene_biotype=protein_coding;locus_tag=NBT03_gp130;old_locus_tag=MPXV-M5312_HM12_Rivers-134 +NC_063383.1 RefSeq CDS 128924 132418 . + 0 ID=cds-YP_010377133.1;Parent=gene-NBT03_gp130;Dbxref=GenBank:YP_010377133.1,GeneID:72551546;Name=OPG151;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp135%3B RNA polymerase%2C 132 kDa subunit (RPO132)%3B similar to VACV-WR A25R and VACV-Cop A24R;gbkey=CDS;gene=OPG151;locus_tag=NBT03_gp130;product=DNA-dependent RNA polymerase subunit rpo132;protein_id=YP_010377133.1 +NC_063383.1 RefSeq sequence_feature 132396 136092 . - . ID=id-NC_063383.1:132396..136092;exon_number=OPG152;gbkey=misc_feature;number=OPG152 +NC_063383.1 RefSeq gene 136138 137667 . - . ID=gene-NBT03_gp131;Dbxref=GeneID:72551547;Name=OPG153;gbkey=Gene;gene=OPG153;gene_biotype=protein_coding;locus_tag=NBT03_gp131;old_locus_tag=MPXV-M5312_HM12_Rivers-137 +NC_063383.1 RefSeq CDS 136138 137667 . - 0 ID=cds-YP_010377134.1;Parent=gene-NBT03_gp131;Dbxref=GenBank:YP_010377134.1,GeneID:72551547;Name=OPG153;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp138%3B major component of IMV surface tubules%3B A-type inclusion protein%3B P4c precursor%3B similar to VACV-WR A28L and VACV-Cop A26L;gbkey=CDS;gene=OPG153;locus_tag=NBT03_gp131;product=Orthopoxvirus A26L/A30L protein;protein_id=YP_010377134.1 +NC_063383.1 RefSeq gene 137718 138050 . - . ID=gene-NBT03_gp132;Dbxref=GeneID:72551548;Name=OPG154;gbkey=Gene;gene=OPG154;gene_biotype=protein_coding;locus_tag=NBT03_gp132;old_locus_tag=MPXV-M5312_HM12_Rivers-138 +NC_063383.1 RefSeq CDS 137718 138050 . - 0 ID=cds-YP_010377135.1;Parent=gene-NBT03_gp132;Dbxref=GenBank:YP_010377135.1,GeneID:72551548;Name=OPG154;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp139%3B IMV surface membrane 14 kDa fusion protein%3B binding to cell surface heparan%3B similar to VACV-WR A29L and VACV-Cop A27L;gbkey=CDS;gene=OPG154;locus_tag=NBT03_gp132;product=IMV surface fusion protein;protein_id=YP_010377135.1 +NC_063383.1 RefSeq gene 138051 138491 . - . ID=gene-NBT03_gp133;Dbxref=GeneID:72551549;Name=OPG155;gbkey=Gene;gene=OPG155;gene_biotype=protein_coding;locus_tag=NBT03_gp133;old_locus_tag=MPXV-M5312_HM12_Rivers-139 +NC_063383.1 RefSeq CDS 138051 138491 . - 0 ID=cds-YP_010377136.1;Parent=gene-NBT03_gp133;Dbxref=GenBank:YP_010377136.1,GeneID:72551549;Name=OPG155;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp140%3B IMV MP/Virus entry%3B similar to VACV-WR A30L and VACV-Cop A28L;gbkey=CDS;gene=OPG155;locus_tag=NBT03_gp133;product=Envelope protein A28 homolog;protein_id=YP_010377136.1 +NC_063383.1 RefSeq gene 138492 139409 . - . ID=gene-NBT03_gp134;Dbxref=GeneID:72551550;Name=OPG156;gbkey=Gene;gene=OPG156;gene_biotype=protein_coding;locus_tag=NBT03_gp134;old_locus_tag=MPXV-M5312_HM12_Rivers-140 +NC_063383.1 RefSeq CDS 138492 139409 . - 0 ID=cds-YP_010377137.1;Parent=gene-NBT03_gp134;Dbxref=GenBank:YP_010377137.1,GeneID:72551550;Name=OPG156;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp141%3B RNA polymerase%2C 35 kDa subunit (RPO35)%3B similar to VACV-WR A31L and VACV-Cop A29L;gbkey=CDS;gene=OPG156;locus_tag=NBT03_gp134;product=DNA-directed RNA polymerase 35 kDa subunit;protein_id=YP_010377137.1 +NC_063383.1 RefSeq gene 139372 139608 . - . ID=gene-NBT03_gp135;Dbxref=GeneID:72551551;Name=OPG157;gbkey=Gene;gene=OPG157;gene_biotype=protein_coding;locus_tag=NBT03_gp135;old_locus_tag=MPXV-M5312_HM12_Rivers-141 +NC_063383.1 RefSeq CDS 139372 139608 . - 0 ID=cds-YP_010377138.1;Parent=gene-NBT03_gp135;Dbxref=GenBank:YP_010377138.1,GeneID:72551551;Name=OPG157;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp142%3B IMV protein%3B similar to VACV-WR A32L and VACV-Cop A30L;gbkey=CDS;gene=OPG157;locus_tag=NBT03_gp135;product=IMV membrane protein A30;protein_id=YP_010377138.1 +NC_063383.1 RefSeq gene 139641 139769 . - . ID=gene-NBT03_gp136;Dbxref=GeneID:72551552;Name=OPG158;gbkey=Gene;gene=OPG158;gene_biotype=protein_coding;locus_tag=NBT03_gp136;old_locus_tag=MPXV-M5312_HM12_Rivers-142 +NC_063383.1 RefSeq CDS 139641 139769 . - 0 ID=cds-YP_010377139.1;Parent=gene-NBT03_gp136;Dbxref=GenBank:YP_010377139.1,GeneID:72551552;Name=OPG158;Note=Viral membrane assembly proteins (VMAP)%3B similar to VACV-Cop A30.5L;gbkey=CDS;gene=OPG158;locus_tag=NBT03_gp136;product=A32.5L;protein_id=YP_010377139.1 +NC_063383.1 RefSeq gene 139768 140205 . + . ID=gene-NBT03_gp137;Dbxref=GeneID:72551553;Name=OPG159;gbkey=Gene;gene=OPG159;gene_biotype=protein_coding;locus_tag=NBT03_gp137;old_locus_tag=MPXV-M5312_HM12_Rivers-143 +NC_063383.1 RefSeq CDS 139768 140205 . + 0 ID=cds-YP_010377140.1;Parent=gene-NBT03_gp137;Dbxref=GenBank:YP_010377140.1,GeneID:72551553;Name=OPG159;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp143%3B Hypothetical protein%3B similar to VACV-WR A33R and VACV-Cop A31R;gbkey=CDS;gene=OPG159;locus_tag=NBT03_gp137;product=CPXV166 protein;protein_id=YP_010377140.1 +NC_063383.1 RefSeq gene 140172 141074 . - . ID=gene-NBT03_gp138;Dbxref=GeneID:72551554;Name=OPG160;gbkey=Gene;gene=OPG160;gene_biotype=protein_coding;locus_tag=NBT03_gp138;old_locus_tag=MPXV-M5312_HM12_Rivers-144 +NC_063383.1 RefSeq CDS 140172 141074 . - 0 ID=cds-YP_010377141.1;Parent=gene-NBT03_gp138;Dbxref=GenBank:YP_010377141.1,GeneID:72551554;Name=OPG160;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp144%3B DNA packaging into virion%3B NTP-binding motif A%3B ATPase/DNA packaging protein%3B similar to VACV-WR A34L and VACV-Cop A32L;gbkey=CDS;gene=OPG160;locus_tag=NBT03_gp138;product=ATPase A32;protein_id=YP_010377141.1 +NC_063383.1 RefSeq gene 141102 141647 . + . ID=gene-NBT03_gp139;Dbxref=GeneID:72551555;Name=OPG161;gbkey=Gene;gene=OPG161;gene_biotype=protein_coding;locus_tag=NBT03_gp139;old_locus_tag=MPXV-M5312_HM12_Rivers-145 +NC_063383.1 RefSeq CDS 141102 141647 . + 0 ID=cds-YP_010377142.1;Parent=gene-NBT03_gp139;Dbxref=GenBank:YP_010377142.1,GeneID:72551555;Name=OPG161;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp145%3B EEV envelope glycoprotein%2C needed for formation of actin-containing microvilli and cell-to-cell spread of virion%3B interacts with VAC A36R%3B EEV membrane phosphoglycoprotein%2C C-type lectin-like domain%3B similar to VACV-WR A35R and VACV-Cop A33R;gbkey=CDS;gene=OPG161;locus_tag=NBT03_gp139;product=EEV glycoprotein (1);protein_id=YP_010377142.1 +NC_063383.1 RefSeq gene 141652 142158 . + . ID=gene-NBT03_gp140;Dbxref=GeneID:72551556;Name=OPG162;gbkey=Gene;gene=OPG162;gene_biotype=protein_coding;locus_tag=NBT03_gp140;old_locus_tag=MPXV-M5312_HM12_Rivers-146 +NC_063383.1 RefSeq CDS 141652 142158 . + 0 ID=cds-YP_010377143.1;Parent=gene-NBT03_gp140;Dbxref=GenBank:YP_010377143.1,GeneID:72551556;Name=OPG162;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp146%3B EEV envelope glycoprotein%2C lectin-like%3B required for infectivity of EEV%2C formation of actin-containing microvilli%2C and cell-to-cell spread of virion%3B C-type lectin-like IEV/EEV glycoprotein%3B similar to VACV-WR A36R and VACV-Cop A34R;gbkey=CDS;gene=OPG162;locus_tag=NBT03_gp140;product=EEV glycoprotein (2);protein_id=YP_010377143.1 +NC_063383.1 RefSeq gene 142202 142732 . + . ID=gene-NBT03_gp141;Dbxref=GeneID:72551557;Name=OPG163;gbkey=Gene;gene=OPG163;gene_biotype=protein_coding;locus_tag=NBT03_gp141;old_locus_tag=MPXV-M5312_HM12_Rivers-147 +NC_063383.1 RefSeq CDS 142202 142732 . + 0 ID=cds-YP_010377144.1;Parent=gene-NBT03_gp141;Dbxref=GenBank:YP_010377144.1,GeneID:72551557;Name=OPG163;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp147%3B MHC class II antigen presentation inhibitor%3B similar to VACV-WR A37R and VACV-Cop A35R;gbkey=CDS;gene=OPG163;locus_tag=NBT03_gp141;product=MHC class II antigen presentation inhibitor;protein_id=YP_010377144.1 +NC_063383.1 RefSeq gene 142778 143464 . + . ID=gene-NBT03_gp142;Dbxref=GeneID:72551558;Name=OPG164;gbkey=Gene;gene=OPG164;gene_biotype=protein_coding;locus_tag=NBT03_gp142;old_locus_tag=MPXV-M5312_HM12_Rivers-148 +NC_063383.1 RefSeq CDS 142778 143464 . + 0 ID=cds-YP_010377145.1;Parent=gene-NBT03_gp142;Dbxref=GenBank:YP_010377145.1,GeneID:72551558;Name=OPG164;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp148%3B IEV but not CEV envelope protein%3B plays critical role for actin tail formation%3B interacts with VAC A33R and A34R%3B IEV transmembrane phosphoprotein%3B similar to VACV-WR A38R and VACV-Cop A36R;gbkey=CDS;gene=OPG164;locus_tag=NBT03_gp142;product=IEV transmembrane phosphoprotein;protein_id=YP_010377145.1 +NC_063383.1 RefSeq gene 143516 144322 . + . ID=gene-NBT03_gp143;Dbxref=GeneID:72551559;Name=OPG165;gbkey=Gene;gene=OPG165;gene_biotype=protein_coding;locus_tag=NBT03_gp143;old_locus_tag=MPXV-M5312_HM12_Rivers-149 +NC_063383.1 RefSeq CDS 143516 144322 . + 0 ID=cds-YP_010377146.1;Parent=gene-NBT03_gp143;Dbxref=GenBank:YP_010377146.1,GeneID:72551559;Name=OPG165;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp149%3B Hypothetical protein%3B similar to VACV-WR A39R and VACV-Cop A37R;gbkey=CDS;gene=OPG165;locus_tag=NBT03_gp143;product=CPXV173 protein;protein_id=YP_010377146.1 +NC_063383.1 RefSeq gene 144398 144577 . + . ID=gene-NBT03_gp144;Dbxref=GeneID:72551560;Name=OPG166;gbkey=Gene;gene=OPG166;gene_biotype=protein_coding;locus_tag=NBT03_gp144 +NC_063383.1 RefSeq CDS 144398 144577 . + 0 ID=cds-YP_010415322.1;Parent=gene-NBT03_gp144;Dbxref=GenBank:YP_010415322.1,GeneID:72551560;Name=OPG166;Note=Hypothetical protein%3B according to YP_233043.1%2C this VACV-WR protein was purified by sucrose gradient centrifugation%3B similar to VACWR161 and VARGAR-A43R;gbkey=CDS;gene=OPG166;locus_tag=NBT03_gp144;product=hypothetical protein;protein_id=YP_010415322.1 +NC_063383.1 RefSeq gene 144574 145407 . - . ID=gene-NBT03_gp145;Dbxref=GeneID:72551561;Name=OPG167;gbkey=Gene;gene=OPG167;gene_biotype=protein_coding;locus_tag=NBT03_gp145;old_locus_tag=MPXV-M5312_HM12_Rivers-150 +NC_063383.1 RefSeq CDS 144574 145407 . - 0 ID=cds-YP_010377147.1;Parent=gene-NBT03_gp145;Dbxref=GenBank:YP_010377147.1,GeneID:72551561;Name=OPG167;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp150%3B integral membrane glycoprotein%3B immunoglobulin-like%3B regulation of the influx of extracellular Ca2+%3B CD47-like%3B similar to VACV-WR A40L and VACV-Cop A38L;gbkey=CDS;gene=OPG167;locus_tag=NBT03_gp145;product=CD47-like protein;protein_id=YP_010377147.1 +NC_063383.1 RefSeq sequence_feature 145423 145856 . + . ID=id-NC_063383.1:145423..145856;exon_number=OPG168;gbkey=misc_feature;number=OPG168 +NC_063383.1 RefSeq sequence_feature 145857 146039 . + . ID=id-NC_063383.1:145857..146039;exon_number=OPG169;gbkey=misc_feature;number=OPG169 +NC_063383.1 RefSeq gene 146113 146778 . - . ID=gene-NBT03_gp146;Dbxref=GeneID:72551562;Name=OPG170;gbkey=Gene;gene=OPG170;gene_biotype=protein_coding;locus_tag=NBT03_gp146;old_locus_tag=MPXV-M5312_HM12_Rivers-151 +NC_063383.1 RefSeq CDS 146113 146778 . - 0 ID=cds-YP_010377148.1;Parent=gene-NBT03_gp146;Dbxref=GenBank:YP_010377148.1,GeneID:72551562;Name=OPG170;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp151%3B secreted protein reducing infiltration of inflammatory cells into the infected area%3B Chemokine binding protein%3B similar to VACV-WR A41L and VACV-Cop A41L;gbkey=CDS;gene=OPG170;locus_tag=NBT03_gp146;product=Chemokine binding protein;protein_id=YP_010377148.1 +NC_063383.1 RefSeq gene 146988 147389 . + . ID=gene-NBT03_gp147;Dbxref=GeneID:72551563;Name=OPG171;gbkey=Gene;gene=OPG171;gene_biotype=protein_coding;locus_tag=NBT03_gp147;old_locus_tag=MPXV-M5312_HM12_Rivers-152 +NC_063383.1 RefSeq CDS 146988 147389 . + 0 ID=cds-YP_010377149.1;Parent=gene-NBT03_gp147;Dbxref=GenBank:YP_010377149.1,GeneID:72551563;Name=OPG171;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp152%3B Profilin-like protein%2C ATI-localized%3B similar to VACV-WR A42R and VACV-Cop A42R;gbkey=CDS;gene=OPG171;locus_tag=NBT03_gp147;product=Profilin domain protein;protein_id=YP_010377149.1 +NC_063383.1 RefSeq gene 147427 148017 . + . ID=gene-NBT03_gp148;Dbxref=GeneID:72551564;Name=OPG172;gbkey=Gene;gene=OPG172;gene_biotype=protein_coding;locus_tag=NBT03_gp148;old_locus_tag=MPXV-M5312_HM12_Rivers-153 +NC_063383.1 RefSeq CDS 147427 148017 . + 0 ID=cds-YP_010377150.1;Parent=gene-NBT03_gp148;Dbxref=GenBank:YP_010377150.1,GeneID:72551564;Name=OPG172;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp153%3B Type I membrane glycoprotein%3B similar to VACV-WR A43R and VACV-Cop A43R;gbkey=CDS;gene=OPG172;locus_tag=NBT03_gp148;product=Type-I membrane glycoprotein;protein_id=YP_010377150.1 +NC_063383.1 RefSeq gene 148037 148261 . + . ID=gene-NBT03_gp149;Dbxref=GeneID:72551565;Name=OPG173;gbkey=Gene;gene=OPG173;gene_biotype=protein_coding;locus_tag=NBT03_gp149;old_locus_tag=MPXV-M5312_HM12_Rivers-154 +NC_063383.1 RefSeq CDS 148037 148261 . + 0 ID=cds-YP_010377151.1;Parent=gene-NBT03_gp149;Dbxref=GenBank:YP_010377151.1,GeneID:72551565;Name=OPG173;Note=Old product: MPXVgp154%3B Hypothetical protein%3B similar to VACV-WR A44R and VACV-Cop A43.5R;gbkey=CDS;gene=OPG173;locus_tag=NBT03_gp149;product=MPXVgp154;protein_id=YP_010377151.1 +NC_063383.1 RefSeq gene 148355 149395 . - . ID=gene-NBT03_gp150;Dbxref=GeneID:72551566;Name=OPG174;gbkey=Gene;gene=OPG174;gene_biotype=protein_coding;locus_tag=NBT03_gp150;old_locus_tag=MPXV-M5312_HM12_Rivers-155 +NC_063383.1 RefSeq CDS 148355 149395 . - 0 ID=cds-YP_010377152.1;Parent=gene-NBT03_gp150;Dbxref=GenBank:YP_010377152.1,GeneID:72551566;Name=OPG174;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp155%3B 3-b-Hydroxy-delta5-steroid dehydrogenase%3B 3 beta-hydroxysteroid dehydrogenase/delta 5->4 isomerase%3B similar to VACV-WR A45L and VACV-Cop A44L;gbkey=CDS;gene=OPG174;locus_tag=NBT03_gp150;product=Hydroxysteroid dehydrogenase;protein_id=YP_010377152.1 +NC_063383.1 RefSeq gene 149442 149819 . + . ID=gene-NBT03_gp151;Dbxref=GeneID:72551567;Name=OPG175;gbkey=Gene;gene=OPG175;gene_biotype=protein_coding;locus_tag=NBT03_gp151;old_locus_tag=MPXV-M5312_HM12_Rivers-156 +NC_063383.1 RefSeq CDS 149442 149819 . + 0 ID=cds-YP_010377153.1;Parent=gene-NBT03_gp151;Dbxref=GenBank:YP_010377153.1,GeneID:72551567;Name=OPG175;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp156%3B virion core protein%3B Inactive Cu-Zn superoxide dismutase-like virion protein%3B similar to VACV-WR A46R and VACV-Cop A45R;gbkey=CDS;gene=OPG175;locus_tag=NBT03_gp151;product=Copper/zinc superoxide dismutase;protein_id=YP_010377153.1 +NC_063383.1 RefSeq gene 149809 150531 . + . ID=gene-NBT03_gp152;Dbxref=GeneID:72551568;Name=OPG176;gbkey=Gene;gene=OPG176;gene_biotype=protein_coding;locus_tag=NBT03_gp152;old_locus_tag=MPXV-M5312_HM12_Rivers-157 +NC_063383.1 RefSeq CDS 149809 150531 . + 0 ID=cds-YP_010377154.1;Parent=gene-NBT03_gp152;Dbxref=GenBank:YP_010377154.1,GeneID:72551568;Name=OPG176;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp157%3B IL-1/TLR signaling inhibitor%3B similar to VACV-WR A47R and VACV-Cop A46R;gbkey=CDS;gene=OPG176;locus_tag=NBT03_gp152;product=Bcl-2-like protein;protein_id=YP_010377154.1 +NC_063383.1 RefSeq sequence_feature 150684 151407 . - . ID=id-NC_063383.1:150684..151407;exon_number=OPG177;gbkey=misc_feature;number=OPG177 +NC_063383.1 RefSeq gene 151509 152123 . + . ID=gene-NBT03_gp153;Dbxref=GeneID:72551569;Name=OPG178;gbkey=Gene;gene=OPG178;gene_biotype=protein_coding;locus_tag=NBT03_gp153;old_locus_tag=MPXV-M5312_HM12_Rivers-158 +NC_063383.1 RefSeq CDS 151509 152123 . + 0 ID=cds-YP_010377155.1;Parent=gene-NBT03_gp153;Dbxref=GenBank:YP_010377155.1,GeneID:72551569;Name=OPG178;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp159%3B thymidylate kinase%3B start of ORF is missing approx. 37 AA compared to CPXVs%3B similar to VACV-WR A49R and VACV-Cop A48R;gbkey=CDS;gene=OPG178;locus_tag=NBT03_gp153;product=Thymidylate kinase;protein_id=YP_010377155.1 +NC_063383.1 RefSeq sequence_feature 152172 152660 . + . ID=id-NC_063383.1:152172..152660;exon_number=OPG179;gbkey=misc_feature;number=OPG179 +NC_063383.1 RefSeq gene 152692 154371 . + . ID=gene-NBT03_gp154;Dbxref=GeneID:72551570;Name=OPG180;gbkey=Gene;gene=OPG180;gene_biotype=protein_coding;locus_tag=NBT03_gp154;old_locus_tag=MPXV-M5312_HM12_Rivers-159 +NC_063383.1 RefSeq CDS 152692 154371 . + 0 ID=cds-YP_010377156.1;Parent=gene-NBT03_gp154;Dbxref=GenBank:YP_010377156.1,GeneID:72551570;Name=OPG180;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp160%3B ATP-dependent DNA ligase%3B similar to VACV-WR A50R and VACV-Cop A50R;gbkey=CDS;gene=OPG180;locus_tag=NBT03_gp154;product=DNA ligase (2);protein_id=YP_010377156.1 +NC_063383.1 RefSeq gene 154412 155416 . + . ID=gene-NBT03_gp155;Dbxref=GeneID:72551571;Name=OPG181;gbkey=Gene;gene=OPG181;gene_biotype=protein_coding;locus_tag=NBT03_gp155;old_locus_tag=MPXV-M5312_HM12_Rivers-160 +NC_063383.1 RefSeq CDS 154412 155416 . + 0 ID=cds-YP_010377157.1;Parent=gene-NBT03_gp155;Dbxref=GenBank:YP_010377157.1,GeneID:72551571;Name=OPG181;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp161%3B Hypothetical protein%3B similar to VACV-WR A51R and VACV-Cop A51R;gbkey=CDS;gene=OPG181;locus_tag=NBT03_gp155;product=M137R;protein_id=YP_010377157.1 +NC_063383.1 RefSeq sequence_feature 155485 156037 . + . ID=id-NC_063383.1:155485..156037;exon_number=OPG182;gbkey=misc_feature;number=OPG182 +NC_063383.1 RefSeq sequence_feature 156355 156916 . + . ID=id-NC_063383.1:156355..156916;exon_number=OPG183;gbkey=misc_feature;number=OPG183 +NC_063383.1 RefSeq sequence_feature 157176 158867 . + . ID=id-NC_063383.1:157176..158867;exon_number=OPG184;gbkey=misc_feature;number=OPG184 +NC_063383.1 RefSeq gene 158917 159858 . + . ID=gene-NBT03_gp156;Dbxref=GeneID:72551572;Name=OPG185;gbkey=Gene;gene=OPG185;gene_biotype=protein_coding;locus_tag=NBT03_gp156;old_locus_tag=MPXV-M5312_HM12_Rivers-162 +NC_063383.1 RefSeq CDS 158917 159858 . + 0 ID=cds-YP_010377158.1;Parent=gene-NBT03_gp156;Dbxref=GenBank:YP_010377158.1,GeneID:72551572;Name=OPG185;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp163%3B EEV envelope and cell membrane glycoprotein hemagglutinin%3B inhibition of the ability of infected cells to fuse%3B interacts with VAC F13L%3B similar to VACV-WR B2R and VACV-Cop A56R;gbkey=CDS;gene=OPG185;locus_tag=NBT03_gp156;product=Hemagglutinin;protein_id=YP_010377158.1 +NC_063383.1 RefSeq sequence_feature 159876 160470 . + . ID=id-NC_063383.1:159876..160470;exon_number=OPG186;gbkey=misc_feature;number=OPG186 +NC_063383.1 RefSeq gene 160622 161533 . + . ID=gene-NBT03_gp157;Dbxref=GeneID:72551573;Name=OPG187;gbkey=Gene;gene=OPG187;gene_biotype=protein_coding;locus_tag=NBT03_gp157;old_locus_tag=MPXV-M5312_HM12_Rivers-163 +NC_063383.1 RefSeq CDS 160622 161533 . + 0 ID=cds-YP_010377159.1;Parent=gene-NBT03_gp157;Dbxref=GenBank:YP_010377159.1,GeneID:72551573;Name=OPG187;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp164%3B serine%3B Ser/Thr Kinase%3B similar to VACV-WR B3R and VACV-Cop B1R;gbkey=CDS;gene=OPG187;locus_tag=NBT03_gp157;product=Ser/thr kinase;protein_id=YP_010377159.1 +NC_063383.1 RefSeq gene 161596 163107 . + . ID=gene-NBT03_gp158;Dbxref=GeneID:72551574;Name=OPG188;gbkey=Gene;gene=OPG188;gene_biotype=protein_coding;locus_tag=NBT03_gp158;old_locus_tag=MPXV-M5312_HM12_Rivers-164 +NC_063383.1 RefSeq CDS 161596 163107 . + 0 ID=cds-YP_010377160.1;Parent=gene-NBT03_gp158;Dbxref=GenBank:YP_010377160.1,GeneID:72551574;Name=OPG188;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp165%3B schlafen-like%3B similar to VACV-WR B4R and VACV-Cop B2R;gbkey=CDS;gene=OPG188;locus_tag=NBT03_gp158;product=Schlafen (1);protein_id=YP_010377160.1 +NC_063383.1 RefSeq gene 163333 165018 . + . ID=gene-NBT03_gp159;Dbxref=GeneID:72551575;Name=OPG189;gbkey=Gene;gene=OPG189;gene_biotype=protein_coding;locus_tag=NBT03_gp159;old_locus_tag=MPXV-M5312_HM12_Rivers-165 +NC_063383.1 RefSeq CDS 163333 165018 . + 0 ID=cds-YP_010377161.1;Parent=gene-NBT03_gp159;Dbxref=GenBank:YP_010377161.1,GeneID:72551575;Name=OPG189;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp166%3B ankyrin-like%3B similar to VACV-WR B5R and VACV-Cop B4R;gbkey=CDS;gene=OPG189;locus_tag=NBT03_gp159;product=Ankyrin repeat protein (25);protein_id=YP_010377161.1 +NC_063383.1 RefSeq gene 165122 166075 . + . ID=gene-NBT03_gp160;Dbxref=GeneID:72551576;Name=OPG190;gbkey=Gene;gene=OPG190;gene_biotype=protein_coding;locus_tag=NBT03_gp160;old_locus_tag=MPXV-M5312_HM12_Rivers-166 +NC_063383.1 RefSeq CDS 165122 166075 . + 0 ID=cds-YP_010377162.1;Parent=gene-NBT03_gp160;Dbxref=GenBank:YP_010377162.1,GeneID:72551576;Name=OPG190;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp167%3B palmitated 42 kDa glycoprotein located both on the membranes of infected cells and on EEV envelope%3B complement control protein-like%3B EEV type-1 membrane glycoprotein%2C protective antigen%3B similar to VACV-WR B6R and VACV-Cop B5R;gbkey=CDS;gene=OPG190;locus_tag=NBT03_gp160;product=EEV type-I membrane glycoprotein;protein_id=YP_010377162.1 +NC_063383.1 RefSeq gene 166161 166667 . + . ID=gene-NBT03_gp161;Dbxref=GeneID:72551577;Name=OPG191;gbkey=Gene;gene=OPG191;gene_biotype=protein_coding;locus_tag=NBT03_gp161;old_locus_tag=MPXV-M5312_HM12_Rivers-167 +NC_063383.1 RefSeq CDS 166161 166667 . + 0 ID=cds-YP_010377163.1;Parent=gene-NBT03_gp161;Dbxref=GenBank:YP_010377163.1,GeneID:72551577;Name=OPG191;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp168%3B Ankyrin-like protein%3B similar to VACV-WR B7R and VACV-Cop B6R;gbkey=CDS;gene=OPG191;locus_tag=NBT03_gp161;product=Ankyrin-like protein (46);protein_id=YP_010377163.1 +NC_063383.1 RefSeq gene 166731 167279 . + . ID=gene-NBT03_gp162;Dbxref=GeneID:72551578;Name=OPG192;gbkey=Gene;gene=OPG192;gene_biotype=protein_coding;locus_tag=NBT03_gp162;old_locus_tag=MPXV-M5312_HM12_Rivers-168 +NC_063383.1 RefSeq CDS 166731 167279 . + 0 ID=cds-YP_010377164.1;Parent=gene-NBT03_gp162;Dbxref=GenBank:YP_010377164.1,GeneID:72551578;Name=OPG192;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp169%3B Virulence%2C ER resident%3B similar to VACV-WR B8R and VACV-Cop B7R;gbkey=CDS;gene=OPG192;locus_tag=NBT03_gp162;product=Virulence protein;protein_id=YP_010377164.1 +NC_063383.1 RefSeq gene 167334 168137 . + . ID=gene-NBT03_gp163;Dbxref=GeneID:72551579;Name=OPG193;gbkey=Gene;gene=OPG193;gene_biotype=protein_coding;locus_tag=NBT03_gp163;old_locus_tag=MPXV-M5312_HM12_Rivers-169 +NC_063383.1 RefSeq CDS 167334 168137 . + 0 ID=cds-YP_010377165.1;Parent=gene-NBT03_gp163;Dbxref=GenBank:YP_010377165.1,GeneID:72551579;Name=OPG193;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp170%3B secreted IFN-g binding protein%3B Soluble IFN-g receptor-like protein%3B similar to VACV-WR B9R and VACV-Cop B8R;gbkey=CDS;gene=OPG193;locus_tag=NBT03_gp163;product=Soluble interferon-gamma receptor-like protein;protein_id=YP_010377165.1 +NC_063383.1 RefSeq gene 168230 168895 . + . ID=gene-NBT03_gp164;Dbxref=GeneID:72551580;Name=OPG195;gbkey=Gene;gene=OPG195;gene_biotype=protein_coding;locus_tag=NBT03_gp164;old_locus_tag=MPXV-M5312_HM12_Rivers-170 +NC_063383.1 RefSeq CDS 168230 168895 . + 0 ID=cds-YP_010377166.1;Parent=gene-NBT03_gp164;Dbxref=GenBank:YP_010377166.1,GeneID:72551580;Name=OPG195;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp171%3B shope fibroma virus T4 protein-like%3B ER-localized apoptosis regulator%3B similar to VACV-WR B10R and VACV-Cop B9R;gbkey=CDS;gene=OPG195;locus_tag=NBT03_gp164;product=Intracellular viral protein;protein_id=YP_010377166.1 +NC_063383.1 RefSeq sequence_feature 169001 169642 . + . ID=id-NC_063383.1:169001..169642;exon_number=OPG196;gbkey=misc_feature;number=OPG196 +NC_063383.1 RefSeq gene 169670 169972 . + . ID=gene-NBT03_gp165;Dbxref=GeneID:72551581;Name=OPG197;gbkey=Gene;gene=OPG197;gene_biotype=protein_coding;locus_tag=NBT03_gp165;old_locus_tag=MPXV-M5312_HM12_Rivers-171 +NC_063383.1 RefSeq CDS 169670 169972 . + 0 ID=cds-YP_010377167.1;Parent=gene-NBT03_gp165;Dbxref=GenBank:YP_010377167.1,GeneID:72551581;Name=OPG197;Note=Taxonomic breadth: chordopoxvirinae%3B Hypothetical protein%3B similar to VACV-Cop-B11R;gbkey=CDS;gene=OPG197;locus_tag=NBT03_gp165;product=CPXV205 protein;protein_id=YP_010377167.1 +NC_063383.1 RefSeq gene 170038 170886 . + . ID=gene-NBT03_gp166;Dbxref=GeneID:72551582;Name=OPG198;gbkey=Gene;gene=OPG198;gene_biotype=protein_coding;locus_tag=NBT03_gp166;old_locus_tag=MPXV-M5312_HM12_Rivers-172 +NC_063383.1 RefSeq CDS 170038 170886 . + 0 ID=cds-YP_010377168.1;Parent=gene-NBT03_gp166;Dbxref=GenBank:YP_010377168.1,GeneID:72551582;Name=OPG198;Note=Taxonomic breadth: poxviridae%3B protein kinase-like%3B similar to VACV-WR B11R and VACV-Cop B12R;gbkey=CDS;gene=OPG198;locus_tag=NBT03_gp166;product=Ser/thr kinase;protein_id=YP_010377168.1 +NC_063383.1 RefSeq gene 170988 172022 . + . ID=gene-NBT03_gp167;Dbxref=GeneID:72551583;Name=OPG199;gbkey=Gene;gene=OPG199;gene_biotype=protein_coding;locus_tag=NBT03_gp167;old_locus_tag=MPXV-M5312_HM12_Rivers-173 +NC_063383.1 RefSeq CDS 170988 172022 . + 0 ID=cds-YP_010377169.1;Parent=gene-NBT03_gp167;Dbxref=GenBank:YP_010377169.1,GeneID:72551583;Name=OPG199;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp173%3B serine protease inhibitor-like%2C SPI-2%3B inhibition of the IL-1b converting enzyme%3B apoptosis inhibition%3B Serpin 1%2C2%2C3%3B similar to VACV-WR B12R and VACV-Cop K2L;gbkey=CDS;gene=OPG199;locus_tag=NBT03_gp167;product=Serpin;protein_id=YP_010377169.1 +NC_063383.1 RefSeq gene 172150 172599 . + . ID=gene-NBT03_gp168;Dbxref=GeneID:72551584;Name=OPG200;gbkey=Gene;gene=OPG200;gene_biotype=protein_coding;locus_tag=NBT03_gp168;old_locus_tag=MPXV-M5312_HM12_Rivers-174 +NC_063383.1 RefSeq CDS 172150 172599 . + 0 ID=cds-YP_010377170.1;Parent=gene-NBT03_gp168;Dbxref=GenBank:YP_010377170.1,GeneID:72551584;Name=OPG200;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp174%3B Hypothetical protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR B13R and VACV-Cop C16L and B15R;gbkey=CDS;gene=OPG200;locus_tag=NBT03_gp168;product=Bcl-2-like protein;protein_id=YP_010377170.1 +NC_063383.1 RefSeq sequence_feature 172685 173697 . + . ID=id-NC_063383.1:172685..173697;exon_number=OPG201;gbkey=misc_feature;number=OPG201 +NC_063383.1 RefSeq sequence_feature 173744 174187 . - . ID=id-NC_063383.1:173744..174187;exon_number=OPG202;gbkey=misc_feature;number=OPG202 +NC_063383.1 RefSeq sequence_feature 174328 174456 . + . ID=id-NC_063383.1:174328..174456;exon_number=OPG203;gbkey=misc_feature;number=OPG203 +NC_063383.1 RefSeq gene 174532 175587 . + . ID=gene-NBT03_gp169;Dbxref=GeneID:72551585;Name=OPG204;gbkey=Gene;gene=OPG204;gene_biotype=protein_coding;locus_tag=NBT03_gp169;old_locus_tag=MPXV-M5312_HM12_Rivers-177 +NC_063383.1 RefSeq CDS 174532 175587 . + 0 ID=cds-YP_010377172.1;Parent=gene-NBT03_gp169;Dbxref=GenBank:YP_010377172.1,GeneID:72551585;Name=OPG204;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp177%3B cell surface antigen and secreted IFN-a%3B IFN-alpha/beta receptor glycoprotein%3B similar to VACV-WR B16R and VACV-Cop B19R;gbkey=CDS;gene=OPG204;locus_tag=NBT03_gp169;product=IFN-alpha/beta-receptor-like secreted glycoprotein;protein_id=YP_010377172.1 +NC_063383.1 RefSeq gene 175656 178019 . + . ID=gene-NBT03_gp170;Dbxref=GeneID:72551586;Name=OPG205;gbkey=Gene;gene=OPG205;gene_biotype=protein_coding;locus_tag=NBT03_gp170;old_locus_tag=MPXV-M5312_HM12_Rivers-178 +NC_063383.1 RefSeq CDS 175656 178019 . + 0 ID=cds-YP_010377173.1;Parent=gene-NBT03_gp170;Dbxref=GenBank:YP_010377173.1,GeneID:72551586;Name=OPG205;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp178%3B ankyrin-like%3B similar to VACV-WR B17R and VACV-Cop B20R;gbkey=CDS;gene=OPG205;locus_tag=NBT03_gp170;product=Ankyrin repeat protein (44);protein_id=YP_010377173.1 +NC_063383.1 RefSeq sequence_feature 178118 178916 . + . ID=id-NC_063383.1:178118..178916;exon_number=OPG206;gbkey=misc_feature;number=OPG206 +NC_063383.1 RefSeq gene 179266 180339 . + . ID=gene-NBT03_gp171;Dbxref=GeneID:72551587;Name=OPG208;gbkey=Gene;gene=OPG208;gene_biotype=protein_coding;locus_tag=NBT03_gp171;old_locus_tag=MPXV-M5312_HM12_Rivers-180 +NC_063383.1 RefSeq CDS 179266 180339 . + 0 ID=cds-YP_010377174.1;Parent=gene-NBT03_gp171;Dbxref=GenBank:YP_010377174.1,GeneID:72551587;Name=OPG208;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp180%3B serine protease inhibitor-like%2C SPI-1%3B apoptosis inhibition%3B Serpin 1%2C2%2C3%3B Actual start may be at position 179%2C074%3B annotated start of ORF is missing approx. 17 AA compared to CPXVs%3B similar to VACV-WR B19R and VACV-Cop K2L;gbkey=CDS;gene=OPG208;locus_tag=NBT03_gp171;product=Serpin;protein_id=YP_010377174.1 +NC_063383.1 RefSeq gene 180518 181090 . + . ID=gene-NBT03_gp172;Dbxref=GeneID:72551588;Name=OPG209;gbkey=Gene;gene=OPG209;gene_biotype=protein_coding;locus_tag=NBT03_gp172;old_locus_tag=MPXV-M5312_HM12_Rivers-181 +NC_063383.1 RefSeq CDS 180518 181090 . + 0 ID=cds-YP_010377175.1;Parent=gene-NBT03_gp172;Dbxref=GenBank:YP_010377175.1,GeneID:72551588;Name=OPG209;Note=Old product: MPXVgp181%3B Hypothetical protein%3B similar to VACV-WR B20R and VACV-Cop C14L;gbkey=CDS;gene=OPG209;locus_tag=NBT03_gp172;product=Virulence protein;protein_id=YP_010377175.1 +NC_063383.1 RefSeq gene 181356 186998 . + . ID=gene-NBT03_gp173;Dbxref=GeneID:72551589;Name=OPG210;gbkey=Gene;gene=OPG210;gene_biotype=protein_coding;locus_tag=NBT03_gp173;old_locus_tag=MPXV-M5312_HM12_Rivers-182 +NC_063383.1 RefSeq CDS 181356 186998 . + 0 ID=cds-YP_010377176.1;Parent=gene-NBT03_gp173;Dbxref=GenBank:YP_010377176.1,GeneID:72551589;Name=OPG210;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp182%3B Surface glycoprotein%3B putative membrane-associated glycoprotein%3B cadherin-like domain%3B similar to VACV-WR B21R;gbkey=CDS;gene=OPG210;locus_tag=NBT03_gp173;product=B22R family protein;protein_id=YP_010377176.1 +NC_063383.1 RefSeq sequence_feature 187317 187743 . + . ID=id-NC_063383.1:187317..187743;exon_number=OPG212;gbkey=misc_feature;number=OPG212 +NC_063383.1 RefSeq sequence_feature 187822 188298 . + . ID=id-NC_063383.1:187822..188298;exon_number=OPG213;gbkey=misc_feature;number=OPG213 +NC_063383.1 RefSeq sequence_feature 188458 188963 . + . ID=id-NC_063383.1:188458..188963;exon_number=OPG214;gbkey=misc_feature;number=OPG214 +NC_063383.1 RefSeq gene 189199 189660 . + . ID=gene-NBT03_gp174;Dbxref=GeneID:72551590;Name=OPG005;gbkey=Gene;gene=OPG005;gene_biotype=protein_coding;locus_tag=NBT03_gp174;old_locus_tag=MPXV-M5312_HM12_Rivers-184 +NC_063383.1 RefSeq CDS 189199 189660 . + 0 ID=cds-YP_010377177.1;Parent=gene-NBT03_gp174;Dbxref=GenBank:YP_010377177.1,GeneID:72551590;Name=OPG005;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp185%3B VAC B15R-like%3B Hypothetical protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR N1R and VACV-Cop C16L and B22R;gbkey=CDS;gene=OPG005;locus_tag=NBT03_gp174;product=Bcl-2-like protein;protein_id=YP_010377177.1 +NC_063383.1 RefSeq gene 190410 190940 . + . ID=gene-NBT03_gp175;Dbxref=GeneID:72551591;Name=OPG016;gbkey=Gene;gene=OPG016;gene_biotype=protein_coding;locus_tag=NBT03_gp175;old_locus_tag=MPXV-M5312_HM12_Rivers-186 +NC_063383.1 RefSeq CDS 190410 190940 . + 0 ID=cds-YP_010377184.1;Parent=gene-NBT03_gp175;Dbxref=GenBank:YP_010377184.1,GeneID:72551591;Name=OPG016;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp187%3B similar to VACV-WR N3R;gbkey=CDS;gene=OPG016;locus_tag=NBT03_gp175;product=Brix domain protein;protein_id=YP_010377184.1 +NC_063383.1 RefSeq long_terminal_repeat 190788 197209 . + . ID=id-NC_063383.1:190788..197209;gbkey=repeat_region;rpt_type=long_terminal_repeat +NC_063383.1 RefSeq gene 191054 192367 . + . ID=gene-NBT03_gp176;Dbxref=GeneID:72551592;Name=OPG015_dup;gbkey=Gene;gene=OPG015_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp176;old_locus_tag=MPXV-M5312_HM12_Rivers-187 +NC_063383.1 RefSeq CDS 191054 192367 . + 0 ID=cds-YP_010377179.1;Parent=gene-NBT03_gp176;Dbxref=GenBank:YP_010377179.1,GeneID:72551592;Name=OPG015_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp188%3B ankyrin-like%3B Ankyrin (CPXV-017)%3B similar to VACV-WR N4R;gbkey=CDS;gene=OPG015_dup;locus_tag=NBT03_gp176;product=Ankyrin repeat protein (39);protein_id=YP_010377179.1 +NC_063383.1 RefSeq gene 192603 194369 . + . ID=gene-NBT03_gp177;Dbxref=GeneID:72551593;Name=OPG003_dup;gbkey=Gene;gene=OPG003_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp177;old_locus_tag=MPXV-M5312_HM12_Rivers-188 +NC_063383.1 RefSeq CDS 192603 194369 . + 0 ID=cds-YP_010377180.1;Parent=gene-NBT03_gp177;Dbxref=GenBank:YP_010377180.1,GeneID:72551593;Name=OPG003_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp189%3B ankyrin-like%3B similar to VACV-WR J1R and VACV-Cop C19L;gbkey=CDS;gene=OPG003_dup;locus_tag=NBT03_gp177;product=Ankyrin repeat protein (25);protein_id=YP_010377180.1 +NC_063383.1 RefSeq gene 194459 195508 . + . ID=gene-NBT03_gp178;Dbxref=GeneID:72551594;Name=OPG002_dup;gbkey=Gene;gene=OPG002_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp178;old_locus_tag=MPXV-M5312_HM12_Rivers-189 +NC_063383.1 RefSeq CDS 194459 195508 . + 0 ID=cds-YP_010377181.1;Parent=gene-NBT03_gp178;Dbxref=GenBank:YP_010377181.1,GeneID:72551594;Name=OPG002_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp190%3B secreted TNF binding protein%3B TNF receptor (CrmB)%3B similar to VACV-WR J2R and VACV-Cop C22L;gbkey=CDS;gene=OPG002_dup;locus_tag=NBT03_gp178;product=Crm-B secreted TNF-alpha-receptor-like protein;protein_id=YP_010377181.1 +NC_063383.1 RefSeq gene 195635 196375 . + . ID=gene-NBT03_gp179;Dbxref=GeneID:72551595;Name=OPG001_dup;gbkey=Gene;gene=OPG001_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp179;old_locus_tag=MPXV-M5312_HM12_Rivers-190 +NC_063383.1 RefSeq CDS 195635 196375 . + 0 ID=cds-YP_010377182.1;Parent=gene-NBT03_gp179;Dbxref=GenBank:YP_010377182.1,GeneID:72551595;Name=OPG001_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp191%3B Chemokine binding protein (Cop-C23L)%3B most abundant secreted protein%3B CC-chemokine binding protein%3B similar to VACV-WR J3R and VACV-Cop C23L and B29R;gbkey=CDS;gene=OPG001_dup;locus_tag=NBT03_gp179;product=Chemokine binding protein;protein_id=YP_010377182.1 diff --git a/data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/pathogen.json b/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/pathogen.json similarity index 84% rename from data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/pathogen.json rename to data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/pathogen.json index fbfa844a..76d79855 100644 --- a/data/nextstrain/mpx/hmpxv-b1/pseudo_ON563414/pathogen.json +++ b/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/pathogen.json @@ -7,10 +7,23 @@ "minSeedCover": 0.1, "gapAlignmentSide": "left" }, + "attributes": { + "name": { + "value": "hMPXV_B1", + "valueFriendly": "Human Monkeypox Lineage B.1*" + }, + "reference": { + "value": "pseudo_ON563414", + "valueFriendly": "MPXV_USA_2022_MA001 in NC_063383 coordinates" + } + }, "compatibility": { "cli": "3.0.0-alpha.0", "web": "3.0.0-alpha.0" }, + "deprecated": false, + "enabled": true, + "experimental": false, "files": { "changelog": "CHANGELOG.md", "examples": "sequences.fasta", @@ -225,6 +238,7 @@ ] } }, + "official": true, "qc": { "frameShifts": { "enabled": true, @@ -271,34 +285,5 @@ "schemaVersion": "3.0.0", "version": { "tag": "unreleased" - }, - "attributes": { - "name": "Human Monkeypox Lineage B.1*", - "reference name": "MPXV_USA_2022_MA001 in NC_063383 coordinates", - "reference accession": "pseudo_ON563414" - }, - "maintenance": { - "website": [ - "https://nextstrain.org", - "https://clades.nextstrain.org" - ], - "documentation": [ - "https://github.com/nextstrain/nextclade_data", - "https://docs.nextstrain.org/projects/nextclade" - ], - "source code": [ - "https://github.com/nextstrain/nextclade_data", - "https://github.com/neherlab/nextclade_data_workflows" - ], - "issues": [ - "https://github.com/nextstrain/nextclade_data", - "https://github.com/nextstrain/nextclade_data/issues" - ], - "organizations": [ - "Nextstrain" - ], - "authors": [ - "Nextstrain team " - ] } } diff --git a/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/reference.fasta b/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/reference.fasta new file mode 100644 index 00000000..f34a701f --- /dev/null +++ b/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/reference.fasta @@ -0,0 +1,2 @@ +>ref_in_coord MPXV_USA_2022_MA001 sequence in NC_063383 coordinates +attttactattttatttagtgtctagaaaaaaatgtgtgacccacgaccgtaggaaactctagagggtaagaaaaatcaatcgtttatagagaccatcagaaagaggtttaatatttttgtgagacctatcgaagagagaaaggataaaaactttttacgactccatcagaaagaggtttaatatttttgtgagacccatcgaagagagaaagagatggttagtcaagatatttttcttagtacaaaagtcaatgttttaaaatatatggacgagaattaatttgtctgtataaaaacttgtgtgaaattatgtactagagaaaaaacgtgagcagtgtcccctacatggattttacagatcatttatattccaaaaatattaactatatacgtttattatatgatgttaacgtgtaaattataaacattattttatgatgcaattgtctgacaacctagattggtataaggatgttgataagctctacgagaatatattgttggacgttatcgtttacgaaatagttgagacatcagaaagaggtttaatatttttgtgagaccatcgaagagagaaagagaataaaaatatttttttttttttttttgtaaaacttttttatgagaccaagagaatacgaatagtgatcatatcgtatcacatattgaaacagaaagaagaagtaacgagaggtaactttttgtgaatgtagttaaatatttttgttttgcaaaccggaatatagtgcccggtcttttttaattcgtggtgcggtgtctgaatcgttcgattaacccaactcatccattttcagatgaatagagttatcgattcagacacatgctttgagttttgttgaatcgatgagtgaagtatcatcggttgcaccttcagatgccgatccgtcgacatacttgaatccatccttgacttcaagttcagatgattcctcacacatgtctccgatacgtacgctaaactctaggttcttgacacattttgtatcaacgatcgttgaaccgatgatatctttgtaactcactttcttatgtgagatgttagacccaagtactggatgggtcttgatgtcactgtctttctcttcttcgctacatctgatgtcgatagacatctcacagtctttgatcatagccagagcttcttcacgcgtgatcgcgggagagtccttaccttgtcccggtgacacgctggacaatctagtattcacagtgtttccatcagaggattcggagatggataaaatctttgggcatttggtgaatccaaagttcatgttaagacccgcaccgacgatagtgtaataagtggtgggatctccttttacaacttcttcggatacctcatcatcttcggtctctgtaacttccgttacggattgacaaatcttatcattggtcggtgtttggtcttgctttgtgactttgataataacatcgattcccatatgatgtttgttttcttcttcagtacacgaggatgaagattgttgaagactagtaggcatagcagctgccactaggcacatgcatgccaggacaatatattgtttcatgattgctattgattgattactgttctagatgattctactttcttaccatataataaattagaatatattttctacttttacgagaaattaattattgtatttattatttataggtaaaaaaacttactataagtgggtgggattctgggaattagtgatcagtttatgtatatcgcaactagcgggcatatggctattgacatcgagaacattacccatatgataagagattgtatcattttcgtagtcttgagtattggtattactatatagtatgtagatgtcgacgctagatagacagtcgcccactagagttaccgtctctgaatgcggcatgatagtatcattctttgttttcgttaactgtttggaagatgaatctttgttgttacatttaatctcgaaattcagagtacatatctttgaagtattctgatatctattttctcctgtaaagaatcctgaagttgctacattattaaggacagagaagtattctgcacgaaagactggatcacaatctttatgattcatggtaatagttagttccgacgttgagatggattcgctgagaccggtagtggtcgtccgagtacacgatgtgtcgttgactggatacaggttaatttccacatcgatatagttaaatgtattgctggttacgacgggttcgcatttatctgtggaagagacggtgtgagaatatgttccgggaccacacggagaacagatgacgtctccggtagacgtgtatccggatactccgtatcctattccacactttgttttagaaatacatgttctacaccctgatgctcctttgagaagacaataatatcctggagagcattcacagattctattgtgagtcgtgttacacgatcgcgtctctacctgattactatcacatcttccgttacaacttagacaagcctgtaaatgattattgtgagatgtaaaggtatccgaaccacacggtgtacattgtgtattagtcttgctatcacataatctgaaagcgtaagttcccggaggacacgatagacaacatagattacggcttctgtattcgttgtctttacactttccattggatggtgcatgtggtgctatatctcttccgtttattattatacatgagagaaacaatatatacgagtataatacggacctcatgatttaataatgtagtaatcgtcgtcttgttactgtttgtttcctacttctccaatcatatagattattttttaaatattttctttctatcatggataatatttgtaatggttctttccgtacaacatactgtttagatggtagtcgcttagcttggttatgatattgcgcataatttccggaggcaaatacgatagtctagattgactatcgatggtagactctaatttattgagtgctttgtcgacgagtttacttttatgctccatcgatagatgacactgttctatgagatcgtcgtacatgggaaatgaaatgcgtttgtctgaatgtatggcttcgagatatgtgtgataccgaatgtcttctgttctcaataccgtatacaagtcggtgtctgagattcgaatctctttgaggagacttatgtcacgactacatttttcgatgatggaatctatcttatcgaatgatatatttttcataaatacacttttatagtcctcgtttaaacagaatttagtatgtagttccgcaaatgactcgtcccttaataggcagtaggctattatcttctttacgtagtgatcgtcgtagggagagaactccgacatcttgtagaacaacgatttaatcataggtagagatactttcagtctgtggtggataatgtcattaacgacatccgccttgtatataatgtttctgttttcaaacaccaagtcgaatactgtcttatcgtctttagtcggaaggttgatgtcgtatccaatgtatacgaggtatgaggcaacattgttattgcaattctggaaggcggtatgaagaggagtcattgtattatagtattcgtctttctgaatgtcgaatctatctagtagataccgtagtatattgagagagcgacttccatatccttgattatgttttatgaatagataaagtagatgttgtccttcttccttttgtaatttcccgtatttttgttcgtgccaattgagtaacattatgagaatatgacctgttgcacaatcgttctttatgtattccatgatgggtgtacaattaagattattacgtatcctcgtatcggctcctcgagataaaagagcatacaccacacgaggactatgtttggtatactgttgaaggtaagtgtgtaacggcgtatttccgattttcgtaaccgcgttaatgtttgctccatgatctattatcgcgtagatgaatcgcttctcagctcgcatcttagtgtgactctttgacttgtaataattgctttcgtggaacgcggatatgtgtttacagtagtaatgaagagaagtgagtccatcctcatcgacgcaattagggtcagatcctttagtcaataatttgtacagaacgtaatagtttaagctcccattgaatttatatctaagataacacagcaatagatcggatgatttactaaagtcatcaatggggtccgttagtatatcaaagatcttgttatcgattgatagtgaatgaatcagatagtggtgtagaggaatatgtccttttttatccttgctatcaaagttacgcatgccgtggcgtaacaatatctttaatacagatggattaaatcgtgtattcatcgtatagcaatgtaatggagagttaccacattttagtcgtttattcagatcgcagtgtttaataactaatttaaacagatgagatgatatatccacatcaaagaatgcgagatacatatgacagacattattgacagaaatgtgaccttcattatcaccgtcgtccataaatgcgttaggtacgtaccacatactatcgttaacgatgcgcacaatctcgtccatttcatccatcttcataatgatttactttttcataattagagaaaaagatcaaggtataaaaattagaagtgttagactataaactaacttatgacttaactaacttatgacttaactaacttatgacttaactaacttatgacttaactaacttatgacttaactaacttatgacttaactaacttatgacttaactaacttatgactattaactcatttcaagaaaggtgggtggatagaactctatatgacagcttgtgaaacaattagatccctaatttctaatggaagttttgataggagattgtcatcagttgatacattgtttattatctcatctattagagcacgtctgtttagagctttagtgacctgctcggttacttctgtgtaaatcttgaatcctttagtgatacactgtgtcaaaactggatgtttagaatacctatgtagaatatgggaagcatgcttgtttttgtctctattatagattaactcatacatggttgtattatgaattttcatctgcctaatgtactccaattcttgtttacaatcaattatataatcaaagagtgatgatgcatacacattacaaagtgaataatctaccatcataaaatacttgatacagagctttatcacatcatggttttcaattgtattattaagtatagctaattttatacagtcaatagacaatggttctctaagcaatatttctaatattttaagatgtgcttccctacgggcgatgacagatcccctatccacggccacgtcaagacatgtatatccattactcattactgcgttgacatttgctccattttctaatagccatgatactaaatctatataacctgcatagatagcgcgataaagcaaggtccttccaccagcatctagttgattgatatcttcaatatatgggatacaaagcttataaatttctaatactgtgggttcatctacaaggaatcccctagtatactgaattattttatatagatctaatttaacatcattttcatctgggataccacaattcaaaataaactcaacaacactactttcctttttacatattcccctaaaataggcattcaagcattctattttatatattacagccccatgatctaccataagatcaacaatgtctatttctacatatgcattagatagatagtaaagtaagagatcttgcacagaattacaattcttaataattatagagaaaatatcttccatataattctttgacactaatgcagatataatatctttatatgtaatatatgcaaacagtctatctactatatactgatcaatattatctctatgaatcctaaaataatcatacagaacatctacaggatcacaaattggttcaaggagaaatctatcaaatattttcctgtcaacaactggttctagaacataacagtcaacacctaatccatgttttttataatcatctaccaaagataatgaccaaagatcgaggtcgtcgtgaaactgctcatcgacagccatgaaatctaccgactccatggtgcgaatcgcactgtcttattcgccattgattttcattttttataattatgtacatgttttccttctattctcaagagtctacaaaaatatattttttcgatatctaagtactaagtttttttactgtttttgttactgtcttccattcttctaactaaagatctgagataaattatacaatcttcgctatcgaaccatttttgtagtctaaagcctgaagtaattaaccaactgtttttattagtggcttttttcgatctatcctcgtcctctcatcatccttatattattatcattattatcatagtctattaaacacaaatcatctacgtttataacaacattctcattattaattagttctgtagaatatctttaataatttggctatacatctgttcaatactatctattgatgatttcttttttaagacttaaactagttatggtaatgacgatgaaatcgagtagtaacttctaataaagacttgatatcattatcatatgtttgatcgtcatagttaatagtgtggctaaatggtactgttaataagtttatagacaatatcatagtattttctttccagaattagattatttttttaaatactgatcctcacaattccgtgatgtagcagtagttggtgcatggtctatatcgttaaaatgtatcatatataatagttttctgacgtggagtacagaattttcgattaatgagttcatggtaaggaagggcaaatgcctgtatataatatacataagttaatagttttttatcatattttctaataccataataaaaattatcattattgcgtttggtagttctgccctatcatctatatcactgtcactctcgctctcactatatcttctaaaattacaaacaactggatattcgataacagcatttgtgtagtttttgtcttttacagtatatacgttattgtcaaaatctaaacaaatattagcataatacatctatctataagatcaggatccatgttcgagcatactagccatgtatatttgtaacttcgtcgtacagcgttagatcaatagaataaacaatcgtgtgacgcaacttttttacgatctagttgtatgagtttatcgtttacataagcaattaacggctttaacagatgatctgagtaataatatacctctgttatacgtttaatgttcacggtcttagtatttttagatatcaattgtgatttacaccatattcgactcccttgtgtgtaacgttagaaattctaaatctatattatctattacagcgtaaaacacattcaatattgtattgttatttttatattatttacacaattaacaatgtattattagtttatattactgaattaataatataaaattcccaatcttgtcataaacacaaaatccattaaaaatgtcgataaaatatctgatgttgttgttcgctgctatgataatcagatcattagccgatagtggtaatgctatcgaaacaacatcgccagaaattacaaacgctacaacagatattccagctatcagattatgtggtccagagggagatggatattgtttacacggtgactgtatccacgctagagatattgacggtatgtattgtagatgctctcatggttatacaggtattagatgtcagcatgtagtattagtagactatcaacgttcaggaaaaccagacactacaacatcatatatcccatctctaggtattgtgcttgtattagtaggcattattattacgtgttgtctattatctgtttatatgttcactcgaagaactaaactacctatacaagatatggttgtgttatattttttataaaatttttttatgagtatttttacaaaaatgtatatgtataaaaaaaatactaagtatacgatgtatcctgtattatttgtatttatctaaacaatacttctgcctctagatgggatacaaaaattttttatttcagcatattaaagtaaaatctagttaccttgaaaatgaatacagtgggtggttccgtatcaccagtaagaacataatagtcgaatacagtatccgattgagattttgcatacaatactagtctagaaagaaatttgtaatcatcctctgtgacaggagtccatatatctgtatcatcgtctagtttttatcagtgtcctatgctatattcctgttatcatcattagttaatgaaaataactctcgtgcttcagaaaagtcaaatattgtatccatacatatatctccaaaactatcacttatacgtttatctttaacgaacatatacctagatggttatttactaacagacattttttcaagatctattgacaataactcctatagtttccacatcaaccaagtaatgatcatctattgttatataacaataacataactcttttccatttttatcagtatctatatcaacgtcgttgtagtgaatagtagtcattgatctattatatgaaacggatatgtctagttaatattttctttgatttaaagtctatagtctttacaaacataatatccttatccgactttatatttcctgtagggtggcataattttattctgcctccacaatcagtgtttccaaatatattactagacaatattccatatagttattagttaagggacccaattagaacacgtacgcgcttattcatcatttggatcgtatttcataaaagttattatgttatagatgtcaacacattctacatttttttaattgtctatatagtatttttctgatattttctataatatcagaattgtcttccataggaagttgtatactattcggaatcagttacatgtttaaataattctctgatgtcattccttatacaatcaaattcattattaaacagtttaatagtctgtagacctttatcgtcgtacatatccattgtcttattagttacgcttatttttatgggttttacgttgctttattatattttataataatgattgtttgacaatgtcgtagtatagatatattattagaggaggtataattataaaaagtttctgagtacgatgttataagaggagaggacacattaacatcatacatcaattaactacattcttataacattgtaatcaaaagaattgcaattttgatgtataacaactgtcaatggaattgtatattacaaattacggtatgttgtaacaacaaataccgatcggtaattgtctctgccgctgtaatagaattaattatatatctattacaccggccttgtatcataataaagttgtggtagtatgatctccatatttataatttagtactttgtatttagtttttttggaatcataaaaaaagttttactaatttaaaatttaaaaagtatttacatttttcactgtttagtcgcggatatggaattcgatcctgtcaaaatcaatacatcatctatagatcatgtaacaatattacaatacatagatgaaccaaatgatataagactaacagtatgcattatccgaaatgttaataacattacatattatatcaatatcacaaaaataaatccacatttggctaatcgatttcgggcttggaaaaaacgtatcgccggaagggactatatgactaacttatctagagatacaggaatacaacaatcaaaacttactgaaactatacgtaactgtcaaaaaaataaaaacatatatggtctatatatacactacaatttagttattaatgtggttattgattggataaccgatgtgattgttcaatcaatattaagagggttggtaaattggtacatagctaataatacatatactccaaatacacccaataatactacaaccatttctgagttggatatcatcaaaatactggataaatacgaggacatgtatagagtaagtaaagaaaaagaatgtggaatttgctatgaagttgtttactcaaaacgattagaaaacgatagatactttggtttattggattcgtgtaatcatatattttgcataacatgtatcaatatatggcatagaacacgaagagaaaccggtgcgtcagataattgtcctatatgccgtacacgttttaaaaaaataacaatgagcaagttctataagctagttaactaataaataaaaagtttaattatcgacgatatatgtcgttatttttctctcatatgaaagattaatttgattctaatataatcttcagtattggatgaatctcaattcaaattaattccattagattagattagattagatcataaataaaaatagtagcacgcactacttcagccaaatattcttttttgaaacgccatctagcgtaatgagaacacaagtgaacctataatgagcaaatttattagtatcggttacatgaaggactttacgtagagtggtgattcctccatctgtggtacgaacggtttcatcttctttgatgccaccacccagatgttctataaacttggtatcctcgtccgatttcatatcatttgccaaccaatacatatagctaaacccaggcatacgttccacacatccggaacaatgaaattctccagaagatgttacaatggctagatttggacatttggtttcaaccgcgttaacatatgagtgaacacacccatacatgaaagcgatgagaaataggattctcatcttgccaaaatatcactataaaaaatttatttatcaattttaaaggtataaaaaaatacttattgttgctcgaatattttgtatttgatggtatacggaagattagaaatgtaggtattatcatcaactgattttatgatggttttatgaattttattatgcttcactattgcatcggaaataatatcatatgcttccacgtatattttattttgttttgactcataatacgcacgtaattctggattattggcatatcgatgaataattttagctccatgctcagtaaatattaatgagaacatagtgttgcctcctaccattatttttttcatctcattcaattcttgattgcagagatctatataatcattatagcgttgacttatggactctggaatcttagacgatgtacagtcatctataatcatggtatatttaatacattgttttatagcataggcattatctacgatattagatacttcactcaatgaatcaatcacacaatctaatgtaggtttatgacataatagcattttcagcagttcaatgtttctagattcgttgatggcaatggttatacatgtatatccgttatttgatctaatgttgacatctgaaccggattctagcagtaaagatactagagattgtttattatatctaacagccttgtgaagaagtgtttctcctcgtttgtcaatcatgttaatgtctttaagataaggtagacaaatgtttatagtactaagaattgggcaaacataagacatgtcacaaagaccctttttgtatgtataagtgtagaaattataacatccatagttggattcacataggtgtccaatcgggatctctccatcatcgagatgattgacggcatctcccccttccttttttagtagatatttcatcgtgtaagaatcaatattaatatttctaaagtatctgtgtatagcctctttatttaccacagctccatattccaacatgcattccactagagggatatcgatatcgccgaatgtcatatactcaattagtatatgttggaggacatccgagttcattgttttcaatatcaaagagatggtttccttatcatttctccatagtggtacaatactacacattattccgtacggctttccattctccaaaaacaattttaccaaatctaaatctacatctttattgtatctataatcactatttagataatcagccataattcctcgagtgcaacatgttagatcgtctatatatgaataagccgtgttatctattcctttcattaacaatttaacgatgtctatatctatatgagatgacttaatataatattgaagagctgtacaatagtttttatctatagaagacggcttgattccgtgattaattagacatttaacaacttccggacgcacatatgctctcgtatccgactctgaatacagatgagcgatgatatacagatgcaatacggtaccacaatttcgtggttgataatcatcatacacgtatccgtactcgtcatcctcataaagaacactgcatccattttctatgaacaaatcaataatttcaggaacaggatcatctgtcattacataattttctataactgaacgatggttttcacatttaacactcaagtcaaatccatgttctaccaacacctttatcaagtcaacgtctacattttttgatttcatatagctgaatatattaaagtcatttatgttgctatatccagtagcttctagtagagccatcgctatatccttattgactttaacatgtctactatttgtgtattcttctattggggtaaactgtctccaatttttatgtaatggattagtgccactatctagtagtagtttgacgacctcaacattattacaatgctcattgaaaaggtatgcgtgtaaagcattattcttgaattggttcctggtatcattaggatctctgtctctcaacatctgtttaagttcatcgagaaccacctcctcattttccagatagtcaaacattttgactgaatagaagtgaatgagctactgtgaactctatacacccgcacaactaatgtcattaaatatcatttttgaatgtatttataccatgtcaaaaacttgtacaattattaataaaaataattagtgtttaaattttaccagttccagattttacacctccgttaacacctccattaaccccactttttacaccactggacgatcctcctccccacattccactgccactagatgtataagttttagatcctttattactaccatcatgtccatggataaagacactccacatgccgccactactaccccctttagacgacatattaataagacaagtttaacaataaaattaatcacgagtaccctactaccaaccactattatatgattacagtaccttgactaaagtctctagtcacaagatcaatactaccaacctacgctattatatgattatagtttctatttttataggaacgcgtacgagaaaatcaaatgtctaagttctaacggtagtgttgataaacgattgttatccgcggatacctcatctatcatgttgtctattttcttactttgttctattaacctattagcattatatattatttgattataaaacttatattgcttattagcccaatctgtaaatatcggattattaacatatcgtttctttgtaggtttatttaacttgtacatcactgtaagcatgtccgtaccatttattttaatttgacacatatcagcaatttctttttcgcagtcggttatatattctatataagatggatacgtatcacatatgtacttatagtctactaatatgaagtacttaatacatattttcagtaacgatttagccttattacctattaataagtgcctgtcgttggataggtaatcaactgttttcttaatacattcgatggttggtaatttactcaaaataatttccaatatcttaatatatatttctgctatttctggtatacatgcatgtgccattataacacaaataccaatacatgtagacccatatgttgttgttatattaatatctgcgccattatctattaaccattctattaggtcaacactatgcgactcgatacaataataaagtatactacgtccatgtttatctattttgtttatatcatcgatatacggcttacaaatttctagtatcgataacacttctgactcgtgaataaataaggtagggaataacggcataatatttattatgttatcatcattaacaactacgtttccattttttaaaatatactctacaactttaggatccctattgtcaaatcttttaaaatatttatttatatgcttaaatctatataatatagctccttccctaatcatacatttgataacattgatgtacactgtatgataagatacatattctgacaatagatcttgtatagaatctgtatatcttttaagaattgaggatattatgacattattacgtaaactattacacaattctaaaatataaaatgtatcatgggcagataatagtttatccactatataattatctattttatgatttttcttcctatattgtttacgtaaatagatagatagaatatgcattagttcattaccgctatagttactatcgaataacacgtcaaatatttcccgtttaatatcgcatttgtcaacataataatagagtatggtacgttcacgataagtataatgacacatctcgttttcgtgcgaaattaaatagtttatcacgtccaaagatgtcacataaccatcttgtgacctagtaataatataataatagagaactgttttacccattctattatcataatcagtggtgtagtcataatctaaataatcaaactcgtcatcccaattaaaataaatataatcagtacattgaatgggtatgatattgtacccatactgtatgttgctacatgtaggtattcctttatccaataatagtttaaatacatctatattaggatttgatgttgtcgcgtatttctctacaatattaataccatttttgatactatttatttctatacctttcgaaattagtaatttcaataagtctatatcgatgttatcagaacatagatattcaaatatatcaaaatcattgatatttttatagtcgactgacgacaataacaaaatcacaacatcgtttttgatattattattttttttggtaacgtatgcctttaatggagtttcaccatcatactcatataatggatttgcaccactttctattaatgattgtgcactactggcatcgatgttaaatgttttacaactatcatagagtatcttatcgttaaccatgattggttgttgatgttatcacattttttggtttctttcatttcagttatgtatggatttagcacgtttgggaagcatgagctcatatgatttcagtactgtagtgtcagtactattagtttcgatcagatcaatgtctagatctatagaatcaaaacacaataggtcagaagataatgaatatctgtacgcttcttcttgtactgtaacttctggttttgttagatggttgcatcgtgctttaacgtcaatggtacaaattttatcctcgctttgtgtatatcatattcgtctctagtataaaattctatattcaaattatcatgcgatgtgtgtacgctaacggtatcaataaacggagcacagcatttagtcaacagtaatccaaaattttttaaagtatatcttaacgaaagaagttgtcatcgttagagtgtggtaaatcattgtctacggtactagatcctcataagtgtatatatctagagtaatatttaatttatcaaatggttgataatatggatgttgtggcaatttcctaatacggaaataagacataaacacgcaataaatctaattgcggacatgttacactccttaaaaaatacgaataaacactttggcttttagtaagtgtcatttaacactatactcatattaatccatggactcataatctctatacgggattaacggatgttctatatacggggatgagtagttctcttctttaactttatactttttactaatcatatttagactgatgtatgggtaatagtgtttgaagagctcgttctcatcatcagaataaatcaatatctctgtttttttgttatacagatgtattacagcctcatatattacgtaatagaacgtgtaatctaccttattaactttcaccgcatagttgtttgcaaatacggttaatcctttgacctcgtcgatttccgaccaatctgggcgtataatgaatcttaactttaatttcttgtaatcattcgaaataatttttagtttgcatccgtagttatctcctctatgtaactgtaaatttctcaacgcgatatctccattaataatgatgtcgaattcgtgttgtatacccatactgaattgatgaactaataccgacggtattaatagtaatttacttttcatctttacatacttggtaatagttttactatcataagtttataaattccacaagctactatggaatataccaaccatcttagtatagaacacatgtcttaaagttattaattaattacatgttgttttatatatcgctacgaatttaaacagaggaatcagttaggaagaaaaaattatctgtcatcatcatcatctattggataacatctctgtattctacgatagagtgctattttaagatgtgacagatccgtgtcatcaaatatatactccattaaaatgattattccggcagcgaacttgatattggatacatcacgacctttgttaatatccacgacaatagacagcaatcccattgttccataaacagtgagtttatctttctttgaagtgatattttgtagagatcttataaaactgtcgaatgacatcgtatttatatctttagctaaatcatatatgttaccatcataatatctaacagcatctatcttaaacgtttccatcgctgtaaagacgtttccgatagatggtctcgtttcatcagtcatactgagccaacaaatgtaatcgtgtataacatctttgatagaatcagactctaaagaaaaggaatcggctttattatacacattcatgataaacttaatgaaaaatgtttttcgttgtttaagttggatgaatagtatgtcttaataattgttattatttcactaattaatatttagtaacgagtacactctataaaaacgagaatgacataactaatcataactagttatcaaagaatgtctaggacgcgtaattttttatggtatagatcctgtaagcgttgtctgtattctggagctattttctctatcgcattagtgagttcagaatatgttataaatttaaatcgaataacgaacataactttagtaaagtcgtctatattaactcttttattttctagccatcgtaataccatgtttaagatagtatattctctagttactacgatctcatcgttgtctagaatatcgcatactgaatctacatccaattttagaaattggtctgtgctacatatctcttctatattattgttgatgtattgtcgtagaaaactattacgtagaccattttctttataaaacgaatatatagtactccaattatctttaccgatatatttgcatacataatccattctctcaatcactacatctttaagagtttggttgttaagatatttggctaaactatataattctattagatcatcaacagaatcagtatatatttttctagatccaaagatgaactctttggcatcctctataatattatcagaaaagatattttcgtgttttagtttatcaagatttaacctgttcatatccatgattaacgacgtcatataaccacataaaataaaaatccattttcatttttagcacaatactattcataattgatattgatgtaatattttgttactttgaacgtaaagacagtacacgggtccgtatctccaacaagcacgtagtaatcaaatttggtgttgttaaacttcgcaatattcatcaatttagatagaaacatatactcatcatctgttttaggaatccatgtattattaccactttccaacttatcattatcccaggctatgtttcgcccatcatcgttgcacagagtgaataattcttttgtattcggtagttcaaatatatgatccatgcatatatcgacaaagctattgtagatgtgatttttcctaaatctaatataaaactcgtttactagcaaacattttcctgatttatcgaccaagacacacatggtttctaaatctatcaagtggtggggatccatagttataacgcagtaacataaattattaccttcttgactgtcgctaatatctatatacttattgttatcgtattggattctacatatagatggcttgtatatcaaagatatagaacacataaccaatttatattctcgctttgtattttcgaatctaaagttaagagatttagaaaacattatatcatcggatgatgatatcactgtttccagagtaggatatattaaagtctttaaagattttgtccgattcaaataaatcactaaataatatcccatattatcatctgttatagtcgtgtcattaaatctattatattttatgaaagatatatcactgctcacctctatatttcgtacatttttaaactgtttgtataatatctctctaatacaatcagatatatctattgtgtcggtagacgataccgttacatttgaattaatggtgttccattttacaacttttaacaagttgaccaattcatttctaatagtatcaaactctccatgattaaatattttaatagtatccattttatatcactacggacataaaccattgtatattttttatgtttattagtgtacacattttggaagtaagttcctggatcggatgtcaccgcagtaatattgttgattatttctgacatcgacgtattatatagttttttaattccatatcttttagaaaagttaaacatccttatacaatttgtggaattaatattatgaatcatggtttttacacatagatctattacaggcggaacatcaattattatggcagcaactagtatcatttctacattgtttatggtgatgtttatcttcttccagcgcatatagtctaatatcgattcaaacgcgtgatagtttataccattcaatataatcgcttcatcctttagatggtgatcctgaatgtgtttaaaaaattatacggagacgccgtaataatttccccattgatagaaaatatcacgctttccattttcttgaagtactaaaagtaattataatataatgtaaaggtttatatattcaatattttttataaaaaaaatcattttgacattaattcctttttaaatttcagtctatcatctatagaaacatattctatgaatttataaaatgcttttacgtatcctatcgtaggtgatagaaccgctaaaaaacctatcgaatttctacaaaagaatctgttatatggtatagggagagtataaaacattaaatgtccgtacttattaaagtattcagtagccaatcctaactctttcgaataattattaatggctcttattctgtacgaatctatttttttgaacaatggacctagtggtatatcttgttctatgtatctaaaataatgtctgactagatccgttagtttaatatccgcagtcatcttgtctagaatggcaaatctaactgcgggtttaggcgtaggcgttagtttagtttctatatctacatctatgtctttatctaacaccaaaaatataatagctaatattttattacaatcatccggatattcttctacgatctcactaactaatgtttctttggttatactagtatagtcacgatcagacaaataaagaaaatcagatgatcgatgaataatacatttaaattcatcatctgtaagatttttgagatgtctcattaaaatattattagtgtcagttctcattatcatatattgacagcagctattacacttattttatttttctgtattttattacttttcaccatatagatcagtcattagatcatcaaaatacttttcaatcatcctaaagagtatggtgaacgaatcttcccatctaatttctgaacgtctaccaatgtctctagccactttggcactaatagcgatcattcgcttaacatcttctacattattaactggttgattcaatctatctagcaatggaccgtcggatagcgtcattctcatgttcttaatcaatgtacatacatcgtcatcatctaccaattcatcaaacaatataagctttttaaaatcatcattataataggatggatcgccgtcatttctccaaagaatatatctaataagtagagtcctcatgcttagtaatttaactattttagttaacaactattttttatgttaaatcaattagtaacaccgctatgtttaatacttattcatattttagttttaggatcgagaatcaatacaaaaattaatacatcaattttggaaatacttagtttccacgtagtcaatgaaacatttgagctcatcgtaaaggacgttctcgtacaagacgtaactataaattggtttatatttgttcaagatagatacaaatccgataacttttttgacgaattctacgggattcactttaaaagtgtcataccgggttctttttattcttttaaacagatcgattgtgtgatgttgattaggtcttttacgaatttgatacagaatagcgtttacatatccaccatagtaatcaatagccatttgttcgtatgtcataaattctttaattatatgacactgtgtattatttagttcgtccttgttcatcattaggaatctatccaatatggcaattatattagaactataactgcgttgtatgcgcatgttgatgtgtctgtttatacaatcaattatactaggatccataccactacaatcgggtaaaattgtagcatcatataccatttctagtactttagattcattgttatccattgcagaggacgtcatgatcgaatccaaaaaaatatattatttttatgttattttgttaaaaataatcatcaaatacttcgtaagatactccttcatgaacataatcagttacaaaacgtttatatgaagtaaagtatctacaatttttacaaaagtcaggatgcataagtacaaagtacgcgataaacggaataataatagatttatctagtttatctttttctatctctttcatagttatatacatggtctcagaagtcggattatgtaacatcagcttcgataaaatgactgggttatttagtcttacacattcgctcatacatgtatgaccgttaactatagagtctacactaaaatgattgaataatagatagtctaccattgtttcgtattcagatagtacagcgtagtacatggcatcttcacaaattatatcattatctaatagatatttgacgcatcttatggatcccacttcaacagccatcttaaaatcggtagaatcatattgctttcctttatcgttaataatttctagaacatcatctctatcataaaagatacaaatattaactgtttgatcagtaataacattgctagtcgatatcaatttgttaataagatgcgctgggctcaatgtcttaataagaagtgtaagaggactatctccaaatttgttttgtttattaacatccgttgatggaagtaaaagatttataatgtctacatacttgactgttttagagcatacaatatggagaggcgtatttccatcatgatctggttttgagggactaattcctagtttcatcatccatgagattgtagaagcttttggattgtctgacataagatgtctatgaatatgatttttgccaaatttatccactatcctggcttcgaatccgatagacattatttttttaaacactctttctgaaggatctgtacacgccaacaacggaccacatccttcttcatcaaccgagttgttaatcttggctccatactgtaccaataaatttattctctctatgacttcatcatctgttcccgagagataatatagaggtgttttattatgtttatcacatgcgtttggatctgcgccgtgcaccagcagcatcgcgactattctattattattaattttagaagctatatgcaatggataatttccatcatcatccgtctcatttggagagtatcctctatgaagaagttcttctataaatcgttcatctagtcctttaatgccacaatacgcatgtagaatgtgataatttccagagggttcgataacttgtagcatattcctaaatacatctaaatttttactattatatttggcataaagagatagataatactcgaccgacataatgttgtgttgtccattatagtataaaaattaatatttctatttctatatatttgcaacaatttactctctataacaaatatcataacttagttcttttatgtcaagaaggcactggtttaattcatctataaatgtcactccataactaccacgcatactatactcagaattatgataaagatatttattcttggggtgtaagtaatggggattaatctttgttggatcagtctctaagttaacacatgtcacacatgatccatttatagttatatcacacgatgatgatttatgaattgattccggaagatcgctattgtattttgtagttccacaattcatttccatacatgttattgtcacactaatattatgatgaactttatctagccgctgagtggtaaacaacagaacagatagtttattatctttaccaacaccctcagccgctgccacaaatctctgatccgtatccatgatggtcatgtttacttttagtccgtatccagtcaacactatgttagcatttctgtcgatatagctttcactcatatgacactcaccaataattgtagaattaatgtcgtaatttacaccaatagtgagttcggcgacaaagtaccagtaccggtaatcttgtcgatgaggacatatagtattcttgtattctaccgaatacccgagagatgcgatacaaaagagtaagactaatttgtaaaccatcttactcaaaaatatgcgacaataggaaatctatcttatacacataattattctatcaattttaccaattagttagtgtaatgttaacaaaaatgtgggataatttaatagtttttccttacacaattgacatacatgagtctgagttcctcgtttttgctaattatttcgtccaatttattattcttgacatcgtcaagatcttttgtataggagtcagacttgtattcaacatgtttttctataatcatcttagctatttcggcatcatccaatagtacattttccagattaacagaatagatattaatgtcgtatttgaacagagcctgtaacatctcaatgtctttattatctatagccaatttgatgtccggaatgaagagaagggaattggtgtttgttgacgtcatatagtcgagcaagagaatcatcatatccacgtgtccattttttatagtggtgtgaatacaactaaggagaatagccagatcaaaaggagatggtatctctgaaagaaagtaggaaacaatacttacatcattaagcatgacagcatgataaaatgaagttttccatccagttttcccatagaacatcagtctccaatttttcttaacaaacagttttaccgtttgcatgttaccactatcaaccgcataatacaatgcggtgtttcctttgtcatcaaattgtgaatcatccattccactgaatagcaaaatctttactattttggtatcttctaatgtggctgcctgatgtaatggaaattcattatctagaagatttttcaatgctccagcgttcaacaacgtacatactagacgcacgttattatcagctattgcataatacaagacactatgaccattgatatccgccttaaatgcatctttgctagagagaaagcttttcagttgcttagacttccaagtattaattcgtgacagatccatgtctgaaacgagacgctaattagtgtatattttttcattttttataattttgtcatattgtaccagaattaataatatctctaatagatctgattagtagatatatggctatcgcaaaacaacatatacacatttaataaaaataatattcattaagaagattcagattccactgtacccatcaatataaaataaaataattattccttacatcgtacccataaacaatatattaagtatattccaccttacccataaacaatataaatccagtaatatcatgtctaatgatgaacacaaatggtgtattaaattccagttcttcaggagatgatctcgccgtagctaccatgatagtagatgcctccgctacagttccttgttcgtctacatctatctttacattctgaaacattttataaatatataatgggtccctagtcatatgtttaaacgacgccttatctggattaaacatactaggagccatcatttcggctatcgacttaatatccctcttgttttcgatagaaaatctagggagtttaagattgtacattttattccctaattgagatgaccaatattctaattttgcaggcgtgatagaatctgtgaaatgggtcatattatcacctattgccaggtacatactaatattagcatccttatacagaaggcgcaccatatcatattcttcgtcatcgattgtgattgtatttccttgcaatttagtaactacgttcatcatgggaaccgttttcgtaccgtacttattagtaaaactagcattgtgtgttttagtgatatcaaacggatattgccacgtacctttaaaatatatagtattaatgattgcccatagagtattatcgtcgagcatagtagaatcaactacattagacataccagatctacgttctactatagaattaattttattaaccgcatctcgtctaaagtttaatctatataggccgaatctatgatattgttgataatacgacggtttaatacacacagtactatcgacgaaactttgatacgttagatctgtgtacgtatatttagatgttttcatcttagctaatccggatattaattctgtaaatgctggacccagatctctttttctcaaattcatagtattcaataattctactctagtattacctgatgcagacaatagcgacataaacatagaaaacgaatacccaaacggtgagaagacaatattatcattatcatcctcatccccattttgaatatttttatacgctaatataccagcattgataaatccctgcagacgatatgcggatactgaacacgctaatgatagtatcaataacgcaatcatgatttttatggtattaataattaaccttatttttatgtttggtataaaaattattgatgtctacacatcctttataatcaactctaatcactttaacttttacagttttccctacaagtttatccctatattcaacatatctatccatatgcatctcttaacactctgccaagatagcttcaaagtgaggatagtcaaaaagataaatatatagagtataatcattctcgtatactctgccctttattacatcgcccgcattgggcaacgaataacaaaatgcaagcatcgtgttaacgggctcgtaaattgggataaaattatgtttttattgtttatctattttattcaagagaatattcaggaagttccttttctggttgtatctcgtcgcagtatatatcatttgtacattgtttcatattttttaatagtctacaccttttagtaggactagtatcgtacaattcatagctgtattttgaattccaatcacgtataaaaatatcttccaattgttgacgaagacctaatccatcatccggtgtaatattaatagatgctccacatatatccgtaaagtaatttcctgtccaatttgatgtacctatatacgccgttttatcggttaccatatattttgcatggtttaccctagaatacggaatgggaggatcagcatctggtacaataaatagctttacttctatatctatgtttttagattttagcatagctatagatcttaaaaagtttctcatgataaacgaagatcgttgccagcaactaatcaatagcttaacggatacttgtctgtctatagcggatcttcttaattcatcttctatataaggccaaaacaaaattttacccgcctttgaataaataataggaataaagttcataacagatacataaacgaatttactcgcatttccgatacatgacaataaagcggttaaatcattggttctttccatagtacataattgttgtggtgcagaagcaataaatacagagtgtggaacaccgcttacgttaatactaagaggatgatctgtattataatacgacggataaaagtttttccaattatatggtagattgttaactccaagataccagtatacctcaaaaatttgagtgagatccgctgccaagttcctattattgaagatcgcaatacccaattccttgacctgagttagtgatctccaatccatgttagcgcttcctaaataaatatgtgtattatcagatatccaaaattttgtatgaagaactcctcctaggatatttgtaatatctatgtatcgtacttcaactccggccatttgtagtctttcaacatcctttaatggtttgttggatttattgacggctactctaactcttactcctcttttgggtaattgtacaatctcgtttaatattaccgtgccgaaattcgtacccacttcatccgataaactccaataaaaagatgatatatctagtgtttttatggtattggatagaatttccctccacatgttaaatgtagtcaaatatactttatcaaattgcatacctataggaatagtctctgtaatcactgcgattgtattatccggattcattttatttgttaaaaaaataatcctatatcacttcactctattaaaaatccaagtttctatttctttcatgactgattttttaacttcatccgtttccttatgaagatgatgtttggcgccttcataaatttttatttccctattacaatttgcatgttgcatgaaataatatgcacctgaaacatcgctaatctcattgtttgttccctggagtatgagagtcggggtgttaatcttgggaattatttttctaaccttgttggtagccttcaagacctgactagcaaatccagccttaattttttcatgattgactaatggatcgtattggtatttataaacttcatccatatctctagatactgattctggacatagctttccgactgacgcatttggtgtaatggttcccataagttttgcagctagcagattcagtcttggaacagcgtctgcattaactagaggagacattagaatcattgctgtaaacaagtttggattatcgcaagcagctagtatagaaattgttgctcccatggaatgacccaataagaagactggaactcctggataagtagatttaatagtcaccacgtgctgtaccacatctctaacatacttaccaaagtcatcaatcatcattttttcaccattacttcttccatggccaatatgatcatgtgagaatactaaaattcctaacgatgatatgttttcagctagttcgtcataacgtccagaatgttcaccagctccatgacttatgaatactaatgccttaggatatgtaataggtttccaatatttacaatatatgtaatcattgtccagattgaacatacagtttgtactcatgattcactatataactatcaatattaacagttcgtttaatgatcatattatttttatgttttattgataattgtaaaaatatacaattaaatcaatatagaggaaggagacggtactgtattttgtgagatagtaatggagactaaatcagattatgaggatgctgttttttactttgtggatgatgatgaaatatgtagtcgcgactccatcattgatctaatagatgaatatatcacgtggagaaatcatgttatagtgtttaataaagatattaccagttgtggaagactgtacaaggaattgataaagttcgatgatgtcgctatacggtactatggtattgataaaattaatgagattgtcgaggctatgagtgaaggagaccactacatcaatcttacagaagtccatgatcaggaaagtctattcgctaccataggaatatgtgctaaaatcactgaacattggggatacaaaaagatttcagaatctaaattccaatcattgggaaacattacagatctgatgaccgacgataatataaacatcttgatactttttctagaaaaaaaaatgaattgatgatataagtgtcttcataacgcattattacgttagcattctattatccagtgttaaaaaaattatcctatcatgtatttgagagtcttatatgtagcaaacatgataactgcaatacccataatctttagatattcacgcgtgctatggatggcattatcccgcggtgcggaaatgtacgttatataatctacaaaataatcatcgcatatagtatgagatagtagagtaaacatttttatcgtttctactgggttcatacatcgtctacccaattcggtaatgaatgaaattgtcgccaatcttacacccaaacccttgttgttcattagtatagtattaacttcattatttatgtcataaactgtaaatgattctgtagatgccatatcacacatgatattcatgtcactattataatcattattaactttatcacaatacgtgttgataatatctacatatgatctagtttttgtgggtaattgtctatacaagtcgtctaaacgttgtttactcatatagtattgaacagccatcattacatggtcccgttccgttgatagataatcgagtatgttagtagacttgtcaaatctatataccatattttctggaagcggatatacatagtcgcgatcatcattatcactagcctcatcctctatatcatgtacatgtacataatctatgatattattatacataaacatcgacaacatactattgtctattatctaagtcctgttgatccaaacccttgatctcctctatctgtactatctagagattgtacttcttcaagttctggataatatatacgttgatagattagctgagctattctatctccagtatttacattaaacgtacattttccattattaataagaatgactcctatgcttcccctataatcttcgtctattacaccgcctcctatatcaatgccttttagggacagaccagacctaggagctattctaccatagcagaacttaggcatggacatactaatatctgtcttaattaactgtcgttctccaggagggatagtataatcgtaagcgctatacaaatcatatccggcagcacccggcgattgcctagtaggtgatttagctctgttagtttccttaacaaatctaactggtgagttaatattcatgttgaacataaaaaatatcattttatttcaaaattatttaccattccattccatcccatatattccatgaataagtgcgattattgtacacttctatagtatctatatacgatccacgataaaatcctcctatcaatagcagtttattatccactatgatcaattctggattatccctcggataaataggatcatctatcagagtccatgtattgctggattcacaataaaattccgcatttctaccaaccaagaataaccttctaccaaacactaacgcacatgatttataatgaggataataagtggatggtccaaactgccactgatcatgattgggtagcaaatattctgtagttgtatcagtttcagaatgtcctcccattacgtatataacattgtttatggatgccactgctggattacatctaggtttcagaagactcggcatattaacccaagcagcatccccgtggaaccaacgctcaacagatgtgggatttggtagacctcctactacgtataatttattgttagcgggtatcccgctagcatacagtctggggctattcatcggaggaattggaatccaattgtttgatatataatttaccgctatagcattgttatgtatttcattgttcatccatccaccgataagatatactacttctccaacatgagtacttgtacacatatggaatatatctataatttgatccatgttcataggatactctatgaatggatacttgtatgatttgcgtggttgtttatcacaatgaaatattatgttacagtctagtatccattttacattatgtatacctctgggagaaagataatttgacctgattacatttttgataagaagtagcagatttcctaatctatttcttcgcctcatataccacttaatgacaaaatcaactacataatcctcatctggaacatttagttcgtcgctttctagaataagtttcatagatagataatcaaaattgtctatgatgtcatcttccagttccaaaaagtgtttggtaataaagtctttagtatgacataagagattggatagtccgtattctatacccatcatgtaacactcgatacaatattcctttctaaaatctcgtaggataaagtttatacaagtgtagatgataaattctacagatgttaatatagaagcacgtaataaattgacgacgttatgactatctatatatacctttccagtatatgagtaaataactatagaagttagactgtgaatgtcaaggtctagacaaaccctcgtaactggatctttattttttgtgtatttttggcgtaaatgtgtgcaaaagtatggagataactttttcaatatcgtagaattgactattatattacctcctatagcttcaataattgttttgaatttcttagtcgtgtacaatgctaatatattcttacagtacacagtattgacaaatatcggcatttatgtttctttaaaagtcaacatctaaagaaaaatgattgtcttcttgagacataactcccattttttggtattcacccacacgtttttcgaaaaaattagtttttccttccaatgatatattttccatgaaatcaaacggattggtaacattgtaaatttttttaaatcccaattcagaaatcaatctatctgcgacgaattctatatatgttttcatcatttcacaattcattcctatgagtttaactggaagagccacagtaagaaattcttgttcaatggataccgcatttgttataataaatctaacggtttcttcactcggtggatgcaataaatgtttaaacatcaaacatgcgaaatcgcagtgcagaccctcgtctctactaattaattcgttagaaaacgtgagtccgggcattaggccacgctttttaagccaaaatatggaagcgaatgatccggaaaagaagattccttctactgcagcaaaggcaataagtctctctccataaccggcgctgtcatgtatccacttttgagcccaatcggccttcttttttacacaaggcatcgtttctatggcattaaagaggtagtttttttcattactatctttaacataagtatcgatcaaaagactatacatttccgaatgaatgttttcaatggccatctgaaatccgtagaaacatctagcctcggtaatctgcacttctgtacaaaatcgttctgctaaattttcattcactattccgtcactggctgcaaaaaacgccaatacatgttttataaaatatttttcgtctggtgttagtttattccagtcattgatatctttagatatatccacttcttccactgtccaaaatgatgcctctgcctttttatacatattccagatgtcatgatattggattgggaaaataacaaatctatttggatttggtgcaaggataggttccataactaaattaacaatagtagtaattttttttcagttatctgtatgacgactgtacttggatcttttgtatatcgctatcgccgcaatcactacaataattacaagtattattgatagcattgttattactactatcataattaaattatcgacattcatgggtgttgaataatcgttatcatcattttgtaattgtgacgtcatactagataaatcatttgtgagattgttgtgggaagcgggcacggaagatgcattatcattattatttaacgcctcccattcggattcacaaatgttacgcacgttcaaagttttatggaaactataattttgtgaaaacagataacaagaaaactcgtcatcgttcaaatttttaacgatagtaaaccgattaaacgtcgagctaatttctaacgctagcgactctgttggatatgggtttccagatatatatcttttcagttcccctacgtatctataatcatctgtaggaaatggaagatatttccatttatctactgttcctaatatcatatgcggtggtgtagaaccattaagcgcgaaagatgttatttcgcatcgtattttaacttcgcaataatttctggttagataacgcactctaccagtcaagtcaatgatattagcctttacagatatattcatagtagtcgtaacgatgactccatcttttagatgtgatactcctttgtatgtaccagaatcttcgtacctcaaactcgatatatttaaacaagttaatgatatattaacgcgttttatgaatgatgatatataaccagaagttttatcctctgtggctagcgctataaccttatcattataataccaactagtgtaattaatatgtgacatgacagtgtgggtacaaatatgtacattatcgtctacgtcgtatttgatacatccgcattcagccaacaaatataaaattacaaaaactctaacgacgtttgtacacatcttgatgcggtttaataaatgttttgatttcaatttattgtaaaaaaagattcggttttatactgttcgatattctcattgcttatattctcatctatcatctccacacagtcaaatccatggttaacatgtacctcatcaaccggtaaaagactatcggattcttctatcatcataactcgagaatatttaatttggtggtcattattaatcaagtcaattatcttatttttaacaaacgtaagtattttactcatttttttataaaaacttttagaaatatacagactctatcgtgtgtctatatcttctttttatatccaatgtatttatgtctgatttttcttcatttatcatatataatggtccaaattctacacgtgcttcggattcatccagatcattaaggttcttataatcgcaacatccttctcttccatcttctacatcttccttcttattcttagcgtcacagaatctaccacagcaggatcccatgacgagagtcacattaaactaattcattttcaattataatatactgattagtaatgacaattaaaataaaaatattcttcataaccggtaagaaagtaaaaagttcacattgaaactatgtcagtagttatacatcatgagatgatatactctattttggtggaggattatatgatataattcgtggataatcattcttaagacacatttcttcattcgtaaatcttttcacattaaatgagtgtccatattttgcaatttcttcatatgatggcggtgtacgtggacgaggctgctcctgttcttgtagtcgtcgactgtcgtgtttgcgtttagatccctccattatcgcgatcgcgtagtgagtactatttataccttgtaattaaatttttttattaattaaacgtataaaaacgttccgtatctgtatttaagagccagatttcgtctaatagaacaaatagctacagtaaaaataactagaataatcgctacacccactagaaaccacggatcgtaatacggcaatcggttttcgataataggtggaacgtatattttatttaaggacttaacaattgtctgtaaaccacaatttgcttccgccgatcctgtattaactatctgtaaaagcatatgttgaccgggaggagccgaacattctccgatattcaatttttgtatatctataatgttattaacctccgcatacgcattacagttcttttctagcttggatactacactaggtacatcatctaaatctattcctatttcctcagcgatagctcttctatccttttccgaaagtaatgaaatcacttcaataaatgattcaaccatgagtgtgaaactaagtcgagaattactcatgcatttgttagttattcggagcgcgcaatttttaaactgtcctataacctctcctatatgaatagcacaagtgacattagtagggatagaatgttgagctaatttttgtaaataactatctataaaaagattatacaaagttttaaactctttagtttctgccatttatccagtctgagaaaatgtctctcataataaatttttccaagaaactaattgggtgaagaatggaaacctttaatctatatttatcacagtctgttttggtacacatgatgaattcttctaatgctgtactaaattcgatatctttttcgatttctggatatgtttttaataaagtatgaacaaagaaatggaaatcgtaataccagttatgttcaactttgaaattgttttttattttcttgttaatgattccagccacttgggaaaagtcaaagtcgtttaatgccgatttaatacgttcattaaaaacaaactttttattctttagatgaattattattggttcattggaatcaaaaagtaagatattatcgggtttaagatctgcatgtaaaaagttgtcacaacagggtagttcgtagattttaatgtataacagagacatctgtaaaaagataaactttatgtattgtaccaaagatttaaatcctaatttgatagctaactcggtatctactttatctgccgaatacagtgctaggggaaaaattataatatttcctctttcgtattcgtaattagttctcttttcatgttcgaaaaagtgaaacatgcggttaaaatagtttataacattaatattactgttaataactgccggataaaagtgggatagtaatttcacgaatttgatactgtcctttctctcgttaaacgcctttagaaaaactttagaagaatatctcaatgagagttcctgaccatccatagtttgtatcaataatagcaacatatgaagaacccgcttatacagagtatgtaaaaatgttaatttatagtttaatcccatggcccacgcacacacgattaattttttttcatctccctttagattgttgtatagaaatttgggtactgtaaactccgccgtagtttccatgggactatataattttgtggcctcgaatacaaattttactacatagttatctatcttaaagactataccatatcctcctgtagatatgtgataaaaatcgtcgtttataggataaaatcgtttatctttttgttggaaaaaggatgaattaatgtaatcattctcttctatctttagtagtgtttccttattaaaattcttaaaataatttaacaatctaactgacggagcccaattttggtgtaaatctaattgggacattatgttgttaaaatataaacagtctcctaatataacagtatctgataatctatggggagacatccattgatattcaggggatgaatcattggcaacacccatttattgtacaaaaagccccaatttacaaacgaaagtccaggtttgatagagataaactattaactattttgtctctgtttttaacacctccacagtttttaatttctttggtaatgaaattattcacaatatcagtatcttctttatctaccagagattttactaacttgataaccttggctgtctcattcaatagggtagtgatatttgtatgtatgatattgatatctttttgaattgtttcttttagaagtgattctttgatggtatcagcatacgaattacaataatgcagaaactcagttaacatgcaggaattatagtaagccaattccaattgttgcctgtattgtattagagtattaatatgcgcaatgatgtccttgcgtttctctgatagaatgcgagcagcgattttggcgttatcatttgacgatatttctggaatgacgaatcctgtttctactaacttcttggtaggacaaagtgaaacaatcaagaaaatagcttctcctcctatttgtggaagaaattgaactcctctagatgatctactgacgatagtatctccttgacagatattggaccgaactacggaagtacctggaatgtaaagccctgaaaccccctcattttttaagcagattgttgccgtaaatcctgcactatgcccaagatagagagctcctttggtgaatccatcactatgtttcagtttaaccaagaaacagtcagctggtctaaaatttccatctctatctaatacagaatccaacttgatgtcagggactatgaccggtttaatgttatatgtaacattgagtaaatccttaagttcataatcatcgttgtcatcagttatgtacgatccaaacaatgtttctaccggcatggtggatacgaagatgctatccatcagaatgtttccctgattagtattttctatatagctattcttctttaaacgattttccgaatcagtaactatgttcatttttttaggagtaggacgtctagccagtatggaagaggattttctagatactctcttcaacatctttgatctcaatggaatgcaaaaccccatggtgtaacaaccaacgataaaaataatattgttttttcactttttataattttaccatctgactcatggattcattaatatctttacaagagctactaacgtataattctttataactaaactgagatatatacaccggatctatggtttccataattgagtaaatgaatgctcggcaataactaatggcaaatgtatagaacaacgaaattatactagagttgttaaagttaatattttctatgagttgttccaataaattatttgttgtgactgcgttcaagtcataaattatcttgatactatccagtaaacagtctttaagttctggaatattatcatcccattgtaaagcccctagttcgactatcgaatatcctgctctgatagcagtttcaatatcgacggacgtcaatactgtaataaaggtggtagtattgtcatcatcgtgataaactacgggaatatggtcgttagtaggtaccgtgactttacacaacgcgatatataactttccttttgtaccatttttaacgtagttgggacgtcctgcagggtattgttttgaagaaatgatatcgagaacagatttgatacgatatttgttggattcctgattattcactataatataatctagacagatagatgattcgataaatagagaaggtatatcgttggtaggataatacatccccattccagtattctcggatactctattgatgacactagttaagaacatgtcttctattctagaaaacgaaaacatcctacatggactcattaaaacttctaacgctcctgattgtgtttcgaatgcctcgtacaaggatttcaaggatgccatagattctttgaccaacgatttagtattgcgtttagcatctgatttttttattaaatcaaatggtcggctctctggtttactaccccaatgataacaatagtcttgtaaagataaaccgcaagaaaatttatacacatccatccaaataaccctagcaccgtcggatgatattaatgtattattatagattttccatccacagttattgggccagtatactgttagcaacggtatatcgaatagattactcatgtaacctactagaatgatagttcgtgtactagtcataatatctttaatccaatctaagaaatctaaaattagatcttttacactattaaagttaacaaaggtattacccgggtacgtggatatcatatatggtattggtccattatcagtaatggctccataaactgatacggcaatggtttttatatgtgtttgatctaatgaggacgaaattcgcgcccacaattcatctctagatatgcatttaatatcgaacggtaacacatcaatctcgggacgcgtatatgtttctaaattcttaatccaaatataatgatgacctatatgccctattatcatactgtcaactatagtatacctagagaactttcgatacatctgctgtttcctgtaatcgttaaattttacaaatctataacatgctaaaccttttgacgacagccattcattaatttctgatatggaatctgtattcttaataccgtatcgttctaaagccagtgctatatctccctgttcgtgggaacgctttcgtataatatcgatcaatggataatatgaagtttttggagaataatatgattcatgatctatttcgtccataaacaatctagacataggaattggaggcgatgatcttaattttgtgcaatgggtcaatcctataacttctaatattgtaatattcatcatcgacataacactatctatgttatcatcgtatattagtataccacgaccttcttcatttcgtgccaaaatgatatacagtcttaaataattacgcaatatctcaatagtttcataattgttagctgttttcatcaaggtttgtatcctgtttaacatgatggcgttctataacgtctctattttctatttttaatttttttaaatttttaacgatttactgtggctagatacccaatctctttcaaatatttttttagccttgcttacaagctgtttatctatactattaaaactgacgaatccgtgattttggtaatgggttccgtcgaaatttgccgaagtgatatgaacatattcgtcgtcgactattaacaattttgtattattctgaatagtgaaaaccttcacagatagatcattttgaacacacaacgcatctagacttctggcggttgccatagaatatacgtcgttcttatcccaattaccaactagaagtctgatcttaactcctctattaatggctgcttctataatggagttgtaaatgtcaggccaatagtagctattaccgtcgacacgtgtagtgggaactatggccaaatgttcaatatctatactagtcttagccgacttgagtttatcaataactacatcagtgtctagatctctagaatatcccaataggtgttctggagaatcagtaaagaacactccacctataggattcttaatatgatacgcagtgctaactggcagacaacaagccgcagagcataaattcaaccatgaattttttgcgctattaaaggctttaaaagtatcaaatcttctacgaagatctgtggccagcggaggataatcagaatatacgcctaacgttttaatcgtatgtatagatcctccagtaaatgacgcgtttcctacataacatctttcatcatcagacacccaaaaacaaccgagtagtagtcccacattattttttttatctatattaacggttataaaatttatatccggggagtgactttgtagctctcccagatttcttttccctcgttcatctagcaaaactattattttaatccctttttcagatacctcttttagtttatcaaaaataagcgctcccctagtagtactcagaggattacaacaaaaagatgctatgtatatatatttcttagctagagtgataatttcgttaaaacattcaaatgttgtcaaatgatcggatctaaaatccatattttctggtagtgtttctaccagcctacattttgctcccgcaggtaccgatgcaaatggccacatttagttaacataaaaacttatatatcctgttctatcaacgattctagaatatcatcggctatatcgctaaaattttcatcaaagtcgacatcacaacctaactcagtcaatatattaagaagttccatgatgtcatcttcgtctatttctatatccgtatccattgtagattgttgaccgattatcgagtttaaatcattactaatactcaatccttcagaatacaatctgtgtttcattgtaaatttataggcggtgtatttaagttggtagattttcaattatgtatcaatatagcaacagtagttcttgctcctccttgattttagcatcctcttcattattttcttctacgtacataatcatgtctaatacgttagacaacacaccgacgatggtggccgccacagacacgaatatgactagaccgatgaccatttaaaaaatactctctagctttaacttaaactgtatcgatcattcttttagcacatgtataatataaaaacattattctatttcgaatttaggcttccaaaaatttttcatccgtaaaccgataataatatatatagacttgttaatagtcggaataaatatattaatgcttaaactatcatcatctccacgattagagatacaatatttacattctttttgctgtttcgaaactttatcaatacacgttaatacaaacccaggaaggagatattgaaactgaggctgttgaaaatgaaacggcgaatacaataattcagataatgtaaaatcatgattccgtattctgatgatattagaactgctaatggatgtcgatggtatgtatctaggagtatctattttaacaaagcatcgatttgctaatatacaattatccttttgattaattgttattttattcatattcttaaaaggtttcatatttatcaattcttctacattaaaaatttccatttttaatttatctagccccgcaatactcctcattacgtttcattttttgtctagaatacccattttgttcatcttggtacatagattatccaattgagaagcgcatttagtagttttgtacattttaagtttattaacgaatcgtcgaaaactagttatagttaacattttattatttgataccctgatattaatacccctgccgttactattatttataactgatgtaacccacgtaacattggaattaattatcgatagtaatgcatcgacacttccaaaattgtctattataaactcaccgataatttttttattgcatgttttcatattcattaggattatcaaatctttaatcttattacgattgtatgcgttgatattacaagacgtcattctaaaagacggaggatttccatcaaatgccagacaatcacgtacaaagtacatggaaataggttttgttctattacgcatcatagattcatataaaacacccgtagaaatactaatttgttttactctataaaatactattgcatctatttcatcgttttgtataacgtctttccaagtgtcaaattccaattttttttcattgatagtaccaaattcttctatctctttaactacttgcatagataggtaattacagtgatgcctacatgccgttttttgaaactgaatagatgcatctagaagcgatgctacactagtcacgatcaccactttcatatttagaatatatgtatgtaaaaatatagtagaatttcattttgtttttttctatgctataaatgaattctcattttgtatccgcacatactccgttttatatcaataccaaagaaggaagatatctggttctaaaagccgttaaagtatgcgatgttagaactgtagaatgcgaaggaagtaaagcttcctgcgtactcaaagtagataaaccctcatcacccacgtgtgagagaagaccttcgtccccgtccagatgcgagagaatgaataaccctggaaaacaagtcccgtttatgagaacggacatgttacaaaatatgtttgctgctaatcgcgacaacgtaacgtcaagacttttgaactaaaatacaattatatctttttcgatattaataaatccgtgtctcccgggttttttatctctttcagtatgtgaatagataggtattttatctctattcatcatcgaatttaagagatccgataaacattgtttgtattctccagatgtcagcatctgatacaacaatatatgtgcacataaacctctggcacttatttcatgtaccttccccttatcactaaggagaatagtatttgagaaatatgtatacatgatattatcatgtattagatatacagaatttgtaacactctcgaaatcacacgatgtgtcggcgttaagatctaatatatcactcgataacacattttcatctagatacactagacattttttaaagctaaaatagtctttagtagtaacagtaactatgcgattattttcatcgatgatacatttcatcggcatattattacgcgtaccatcaaagactataccatgtgtatatctaacgtattctagcatagttgccatacgtacattaaacttttcaggatctttggatagatcttccaatctatctatttgagaaaacatttttatcatgttcaatagttgaaacgtcggatccactatatagatattatctataaagattttaggaactatgttcatggtatcctggcgaatattaaaactatcaatgatatgattatcgttttcatcttttatcaccatatagtttctaagatatgggattttacttaatataatattatttcccgtaataaattttattagaaatgccaaatctataagaaaagtcctagaattagtctgaagaatatctatatcaccgtaccgtatatttggattaattagatatagagaatatgatccgtaacatatacaacttttattatgacgtctaagatattcttccatcaacttattaacatttttgactagggaagatacattatgacgtcccattacttttgccttgtctattacagcgacgttcatagaatttagcatatctcttgccaattcttccattgatgttacattataagaaattttagatgaaattacatttggagctttaatagtaagaactcctaatatatccgtgtatgtggtcactaatacagattgtagttctataatcgtaaataatttacctatattatatgtttgagtttgtttagaaaagtagctaagtatacgatcttttatttctgatgccgatgtatcaacatcgaaaaaaaatctttttttattcttttttactaacgatacgaatatgtctttgttaaaaacagttattttctgaatatttctagcttgtaattttaacatatgatattcgttcacactaggtactctgcctaaataggtttctataatctttaatgtaatattaggaagagtattctgatcaggattcctattcattttgaggatttaaaactctgattattgtctaatatggtctcaacacaaactttttcacagagtgatagagtttttgataactcgtttttcttaagaaatataaaactactgtctccagagctcgctctatcttttattttatctaattcgatacaaactcctgatactggttcagaaagtaattcattaattttcagtcctttatagaagatatttaatatagataatacaaaatcttcagttcttgatatcgatctgattgatcctagaactagatatattaataacgtgctcattaggcagtttatggcagcttgataattagatatagtatattccagttcatatttattagataccgcattgcccagattttgatattctatgaattcctctgaaaataaatccaaaataactagacattctattttttgtggattagtgtactctcttccctctatcatgttcactactggtgtccacaatgataaatatctagagggaatataatatagtccatatgatgccaatctagcaatgtcgaataactgtaattttattcttcgctcttcattatgaattgaatcttgaggtataaacctaacacaaattatatcattagacttttcgtatgtaatgtctttcatgttataagtttttaatcctggaatagaatctattttaatgaggcttttaaacgcagcgttctccaacgagtcaaagcataatactctgttggttttcttatattcaatattacgattttcttctttgaatggaataggtttttgaattagtttataattacaacataatagataaggaagtgtgtaaatagtacgcggaaaaaacataatagctcccctgttttcatccatggttttaagtaaatgatcactggcttctttagtcaatggatattcgaacattaaccgtttcatcatcattggacagaatccatatttcttaatgtaaagagtgatcaaatcattgtgtttattgtaccatcttgttgtaaatgtgtattcggttatcggatctgctcctttttctattaaagtatcgatatcgatctcgtctaagaattcaactatatcgacatatttcatttgtatacacataaccattactaacgtagaatgtataggaagagatgtaacgggaacagggtttgttgattcgcaaactattctaatacataattcttctgttaatacgtcttgcacgtaatctattatagatgccaagatatctatataattattttgtaagatgatgttaacaatgtgatctatataagtagtgtaataattcatgtatttcgatatatgttccaactctgtctttgtgatgtctagtttcgtaatatctatagcgtcctcaaaaaatatattcgcatatattcccaagtcttcagttctatcttctaaaaaatcttcaacgtatggaatataataatctattttacctcttctgatgtcattaatgatatagtttttgacactattttccgtcaattgattcttattcactatgtctaaaaaccggatagcgtccctaggacgaactactgccattaatatctctattatagcttctggacataaatcatctattataccagaattaatgggaactattccgtatctatctaacatagttttaagaaagtcagaatctaagacctgatgttcatatattggttcatacatgaaatgatctctattgatgatagtgactatttcattctctgaaaattggtaactcattctatacacgctttccttgttgataaaggatagtatatactcaatggaatttgtaccaacaaactgttctcttatgaatcgtatatcatcatctgaaatgatcatgtaaggcatacatttaacaataagagacttgtctcctgttatcaatatactattcttgtgataatttatgtgtgcggcaaatttgtccacgttctttaattttgttatagtagatatcaaatccaatggagatacagttcttggcttaaacagatatagtttttctggaacgaattctacaacattattataaaggactttgggtatataagtgggatgaaatcctattttaattaatgcgatagccttgtcctcgtgcagatatccaaacgcttttgtgatagtatggcattcattgtctagaaacgctctacgaatatctgtaacagatatcatctttagagaatactagtcgcgttaatagtactaaaatttgtattttttaatctatctcaataaaaaattaatatgtatgattcaatgtataactaaactactaactgttattgataactagaatcagaatctaatgatgacataactaagaagtttatctacagccaatttagctgcattatttttagcatctcgtttagattttccatctgccttatcgaatactcttccgtcaatgtctacacaggcataaaatgtaggagagttactaggccccactgattcaatacgaaaagaccaatctctcctagttatttgacagtactcattaataacggtgacagggttaacacctttccaataaataatttttttaaccggaataacatcatcaaaagacttatgatcctctctcattgatttttcgcgggatacatcatctattatagcatcagcatcagaatctgtaggccgtgtatcagcatccattgtcgtagaccaacgaggaggagtatcgttggagctgtaaaccatagcactacgttgaagatcatacagagctttattaacttctcgcttctccatattaagttgtttagttagttgtacagcagtagctccttagtccaatgtttttaataaccgcacacaatctctgtgtcagaacgctcgtcaatatagatcttagaaatttttttagagagaactaacgcaactagcaataaaactgatcttattttatcattttttttattcatcatcctctggtggttcgtcgttcctatcgaatgtagctctgattaacccgtcatctataggtgatgctggttctggagattctggaggagatggattattatctggaagaatctctgttatttccttgttttcatgtatcgattgcgttgtaacattaagattgcgaaatgctctaaatttgggaggcttaaagtgttgtttacaatctctacacgcgtgtctaactaatggaggttcatcagcggctctagtttgaatcatcatcggtgtagtattcctacttttacagttaggacacggtgtattgtatttctcgtcgagaacgttaaaataatcgttgtaactcacatcctttattttatctatattgtattctactcctttcttaatgcattttataccgaacaagagatagcgaaggaattctttttcggtaccgctagtacccttaatcatatcacatagtgttttatattctaaatgtgtggcaatggacggtttatttctatacgatagtttgtttttggaatcctttgagtattctataccaatattattctttgattcgaatttagtttcttcgatattagattttgtattacctatattcttgatgtagtactttgatgatttttccatggcccattctattaagttttccaagttggcatcatccacatattgtgatagtaattctcggatatcagtagtgactaccgccattgatatttgttcatttgatgagtaactactaatgtatacattttccatttataacacttatgtattaactttgtttatttatattttttcattattatgttgatattaataatcgtattgtggttatatggctacaatttcataatgagttgaagtcagtgtcctatgatcaatgacgatagctttactctgaaaagaaagtatcaaatcgatagtgcagagtcaacaatgaaaatggataagacgatgacaaagtttcagaatagagtcaaaatggtaaaagaaataaatcagacgataagagcagcacaaactcattacgagacattgaaactaggatatataaaatttaagggaatgattaggactactactctagaagatatagcaccatctattccaaataatcagaaaacttataaactattctcggacatttcagtcattggcaaagcatcacagaatccgagtaagatgatatatgctcgctgctttacatgtttcccaatttgtttggagatgaccatagattcatttgttatagaatgcatccaacattgttcatgatatagttgaatcatgtatgcctgttcgtatgcctgtggctaagatactgtgtaaagaaatggtaaataaatactttgagaatctttaagagtgcattgactttgttagtgaataggcattccatctttctccaatactaattcaaattgttaaattaataatggaatagtataaatagttattagtgataggatagtaaacataattattagaatagtagtgtagtatcatagataactctcttctataaaaaatggattttattcgtagaaagtatcttatatacacagtagaaaataatatagattttttaaaggatgatacattaagtaaagtaaacaattttaccctcaatcatgtactagctctcaagtatctagttagcaattttcctcaacatgttattactaaggatgtattagctaataccaatttttttgttttcatacatatggtacgatgctgtaaagtatacgaagcggttttacgacacgcatttgatgcacccacgttgtacgttaaagcattgactaagaattatttatcgtttagtaacacaatacagtcgtacaaggaaacagtgcataaactaacacaagatgaaaaatttttagaggttgccgaatacatggacgaattaggagaacttataggcgtaaattatgacttagttcttaatccattatttcacggaggggaacccatcaaagatatggaaatcatttttttaaaactgtttaagaaaacagacttcaaagttgttaaaaaattaagtgttataagattacttatttgggcatacctaagcaagaaagatacaggcatagagtttgcggataatgatagacaagatatatatactctatttcaacaaactggtagaatagtccatagcaatctaacagaaacgtttagggattatatctttcccggagataagactagctattgggtgtggttaaacgaaagtatagctaatgatgcggatatcgttattaatagacccgccattaccatgtatgataaaattcttagttatatatactctgagataaaacagggacgcgttaataaaaacatgcttaagttagtttatatctttgagcctgaaaaagatatcagagaacttctgctagaaatcatatatgatattcctggagatatcctatctattattgatgcaaaaaacgacgattggaaaaaatattttattagtttttacaaagctaattttattaacggtaatacatttattagtgatagaacgtttaacgatgacttattcagagttgttgttcaaatagatcccgaatatttcgataatgaacgaattatgtctttattctatacgagtgctgcggacattaaacgatttgatgagttagatattaataacagttatatatctaatataatttatgaggtgaacgatatcacattagatacaatggatgatatgaagaagtgtcaaatctttaacgaggatacgttgtattatgttaaggaatacaatacatacctgtttttgcacgagtcggatcccatggtcatagagaacggaatactaaagaaactgtcatctataaaatccaagagtagacggctgaacttgtttagcaaaaacattttaaaatattatttagacggacaattggctcgtctaggtcttgtgttagatgattataaaggagacttattagttaaaatgataaaccatctcaaatctgtggaggatgtatccgcattcgttagattttctacagataaaaaccctagtattcttccatcgctaatcaaaactattttagctagttataatatttccatcatcgtcttatttcaaaggtttttaagagataatctatatcatgtagaagaattcttggataaaagcatccatctaaccaagacggataagaaatatatacttcaattgataaggcacggtagatcatagaacaaaccaaatatattattaataatttgtatatacatagatataattatcacatattaaaaaataacacatttttgataaatggaaaccgttgcaacaattcagactcccaccaaattaatgaataaagaaaatgcagaaatgattttggaaaaaattgttaatcatatagctatgtatattagtgacgaatcaatatattcagaaaataatcctgaatatattgattttcgtaacagatacggagactatagatctctcattataaaaagtgatcacgagtttgtaaagctatgtaaagatcatgcagagaaaagttctccagaaacgcaacaaatgattatcaaacacatatacgaacaatatcttattccagtatctgaagtactattaaaacctataatgtccatgggtgacatatttacatataacggatgtaaagacaatgaatggatgctagaacaactctctaccctaaactttaacaatctctacacatggaactcatgtagcataggcaatgtaacgcgtctgttttatacattttttagttatctgatgaaagataaactaaatatataagtataatcccattctaatactttaacctgatgtattattacctgcatcttattagaatattaacctaactaaaagacataaaaagcggtaggatataaatattatggccgcaaccgttccgcgttttgacgatgtgtacaaaaatgcacaaagaagaattctagatcaagaaacattttttagtagaggtctaagtagaccgttaatgaaaaacacatatctatttgataattacgcgtatggatggataccagaaactgcaatttggagtagtagatacgcaaacctagatgctagtgactattatcccatttcgttgggattacttaaaaagtttgaatttctcatgtctctatataaaggtcctattcccgtatatgaagaaaaagtaaatactgaattcattgctaatggatctttctccggtagatacgtatcatatcttagaaagttttctgcccttccaacaaacgagtttattagttttttattattgacctccatccctatctataatatcttattctggtttaaaaacacacagtttgatattactaaacacacattattcagatacgtctatacagataataccaaacaccttgcgttggctaggtatatacatcaaacaggagactataagcctttgtttagtcgtctcaaagagaattatatatttactggtcccgttccaataggtatcaaagatatagatcaccctaatcttagtagagcaagaagtccatccgattatgagacattagctaatattagtactatattgtactttaccaagtatgatccagtattaatgtttttattgttttacgtacctgggtattcaattactacaaaaattactccagccgtagaatatctaatggataaactgaatctaacaaagagcgacgtacaactgttgtaaattattttatgcttcgtaaaatgtaggtcttgaaccaaacattctttgaaaaaatgagatgcataaaactttattatccaatagattaactatttcagacgtcaatcgtttaaagtaaacttcgtaaaatattctttgattgctgccgagtttaaaacttctatcgataattgtttcatatgttttaatatttacaagttttttggtccatggtacattagctggacagatatatgcaaaataatatcgttctccaagttctatagtctctggattgtttttattatattcagtaaccaaatacatattagggttatctgcggatttataatttgagtgatgcattcgactcaacataaataattctagaggagacgatctactatcaaattcggatcgtaaatctgtttctaaagaacggagaatatctatacatacctgattagaattcatccgtccttcagacaacatctcagacagtctggtcttgtatgtcttaatcatattcttatgaaacttggaaacatctcttctagtttcactagtacctttattaattctctcaggtacagattttgaattcgacgatgccgagtatttcatcgttgtatatttcttcttcgattgcataatcaaattcttatataccgcctcaaactctattttaaaattattaaacaatactctactattaatcagtcgttctaactcctttgctatttctatggacttatctacatcttgactgtctatctctgtaaacacggagtcggtatctccatacacgctacgaaaacgaaatctataatctataggcaacgatgttttcacaatcggattaatatctctatcgtccatataaaatggattacttaatgtattggcaaaccgtaacataccgttggataactctgctccatttagtaccgattctagatacaatatcattctacgtcctatggatgtgcaactcttagccgaagcgtatgagtatagagcactatttctaaatcccatcagaccatatactgagttggctactatcttgtacgtatattgcatggaatcatagatggccttttcagttgaactggtagcctgttttaacatctttttatatctggctctctctgccaaaaatgttcttaatagtctaggaatggttccttctattgatctatcgaaaattgctatttcagagatgaggttcggtagtctaggttcacaatgaaccgtaatatatctaggaggtggatatttctgaagcaagagttgattatttatttcttcttccaatctattggtactaacaacgacaccgactaatgtttccggagatagatttccaaagatacacacattaggatacagactgttataatcaaagattaatacattattactaaacattttttgttttggagcaaataccttaccgccttcataaggaaacttttgttttgtttctgatctaactaagatagttttagtttccaacaatagctttaacagtggacccttgatgattgtactcgctctatattcgaataccatggattgaggaagcacatatgttgccgcaccagcgtctgtttttgtttctactccataatactcccacaaatactgacacaaacaagcatcatgaatacagtatctagccatatctaaagctatgtttagattataatccttatacatctgagctaaatcaatgtcatcctttccgaaagataatttatatatatcattaggtaaagtaggacatgatagtacgactttaaatccattttccaaaatatctttacgaattactttacatataatatcctcatcaacagtcacgtaattacctgtggttaaaacctttgcaaatgtatcggctttgcctttcgcgtccgtagtatcgtcaccgatgaacgtcatttctctaactcctctatttaatactttacccatgcaactgaacgcgttcttggatatagaatccaatttgtacgaatccaatttttcagatttttgaatgaatgaatatagatcgaaaaatatagttccattattgttattaacgtgaaacgtagtattggccatgccgcatactcccttatgactagactgatttctctcataaatacagagatgtacagcttcctttttgtctggagatctaaagataatcttctctcctgttaataactctagacgattagtaatatatctcagatcaaagttatgtccgttaaaggtaacgacgtagtcgaacgttagttccaacaattgtttagctattcgtaacaaaactatttcagaacatagaactagttctcgttcgtaatccatttccattagcgactgtatcctcaaacatcctctatcgacggcttcttgtatttcctgttccgttaacatctcttcattaatgagcgtaaacagtaatcgtttaccacttaaatcgatataacagtaacttgtatgcgagattgggttaataaatacagaaggaaacttcttatcgaagtgacactctatatctagaaataagtacgatcttgggatatcgaatctaggtatttctttagcgaaacagttacgtggatcgtcacaatgataacatccattgttaatctttgtcaaatattgctcgtccaacgagtaacatccgtctggagatatcccgttagaaatataaaaccaactaatattgaaaaattcatccatggtggcattttgtatgctgcgtttctttggctcttctatcaaccacatatctgcgacggagcattttctatctttaatatctagattataacttattgtctcgtcaatgtctatagttctcatctttcccatcggcctcgcattaaatggaggaggagataatgactgatatatttcgtccgtcactacgtaataaaagtaatgaggaaatcgtataaatacggtctcgccatttcgacatctggatttcagatataaaaatctgttttcaccgtgactttcaaaccaattaatacacctaacatccatttctagaatttagaaatatattttcatttaaatgaatcccaaacattggggaagagccgtatggaccattatttttatagtactttcgcaagcgggtttagacggcaacatagaagcgtgtaaacgaaaactatatactatagtcagcactcttccatgtcctgcatgtagacgacacgcgactatcgctatagagaacaataatgtcatgtctagcgatgatctgaattatatttattattttttcatcagattatttaacaatttggcatttgatcccaaatacgcaatcgatgtgtcaaaggttaaacctttataaacttaacccattataaaacttatgattagtcacgactgaaataaccgcgtgattattttttggtataattctacacggcatggtttctgtgactatgaattcaacacctgttatcttagtgaaatctttaacaaacagcaagggttcgtcaaagacataaaactcattgtttacgatcgaaatagaccccctatcacacttaaaataaaaaatatccttatcctttaccaccaaataaaattctgattggtcaatgtgaatgtattcacttaacagttccacaaatttatttattaactccgaggcacatacatcgtcggtattttttatgacaaactttactcttccagcatccgtttctaaaaaaatattaacgagttccatttatatcatccaatattattgaaatgacgttgatggacagatgatataaataagaaggtacagtacctttgtccaccatctcctccaattcatactctattttgtcattaactttaatgtgtgaaaacagtacgccacatgcttccatgacagtgtgtaacactttggatacaaaatgtttgacattagtataattgtccaagactgtcaatctataatagatagtagctataatatattctatgatggtattgaagaagatgacaaccttggcatattgatcatttaacacagacatggtatcaacaaatagcttaaatgaaagagaatcagtaattggaataagcgtcttctcgatgtagtgtccgtataccaacatgtctgatattttgatgtattccattaaattatttagttttttctttttattctcgttaaacagaatttctgtcaatggaccccaacatcgttgacctattaagttttgattgatttttccgtgtaaggcgtatctagtcagatcgtatagcctatccaataatccatcgtctgtgcgtagatcacatcgtacactttttaattttctatagaagagtgacagacatctggagcaattacagacagcaatttctttattctctacagatgtaagatacttgaagatattcctatgatgatgcagaattttggataacacggtattgatggtatctgttaccataattcctttgactgatagtgtcaaagtacaagatttccaatcttttgcaattttcagtaccattatctttgttttgatatctatatcagacagcatggtacgtctgacaacacagggattaagacggaaagatgaaatgattctctcaacatcttcaatagataccttgctattttttttggcattatctatatgtgagagaatatcctctagagaatcagtatcctttttgatgatagtggatctcaatgacatgggacgtctaaaccttcttattctatcaccagattgcatggtgatttgtcttctttcttttatcatgatgtaatctctaaattcatcggcaaattgtctatatctaaaatcataatatgagatgtttacctctacaaatatctgttcgtccaatgttagagtatctatatcagttttgtattccaaattaaacatggcaacggatttaattttatattcctctattaagtcctcgtcgataataacagaatgtagataatcatttaatccatcgtacatggttggaagatgctcgttgacaaaatctttaattgtcttgatgaaggtgggactatatctaacatcttgattaataaaatttataacattgtccataggatactttgtaactagttttatacacatctcttcattggtaagtttagacagaatatcgtgaacaggtggtatattatattcatcagatatacgaagaataatgtccaaatctatattgtttaatatattatatagatgtagtgtagctcctacaggaatatctttaactaagtcaatgatttcatcaacagttagatctattttaaagttaatcatataggcattgatttttaaaaggtatgtagccttgactacattctcattaattaaccattccaagtcactgtgtgtaagaagattatattctatcataagcttgactacatttggtcccgataccattaaagaattcttatgatataaggaaacagcttttaggtactcatctactctacaagaattttggagagccttaacgatatcagtgacgtttattatttcaggaggaaagaacctaacattgagaatatctgaattaatagcttccagatacagtgattttggcaatagtccgtgtaatccataatccagtaacacgagctggtgcttgctagacaccttttcaatgtttaatttttttgaaataagctttgataaagccttcctcgcaaattccggatacatgaacatgtcgccaacatgattaagtattgtttttcattatttttatattttctcaacaagttctcaataccccaatagataatagaatatcacccaatgcgtccatgttgtctatttccaacaggtcgctatatccaccaatagaagttttcccaaaaaagattctaggaacagttctaccaccagtaatttgttcaaaatagtcacgcaattcattttcgggtttaaattctttaatatctacaatttcatacgctcctcttttgaaactaaacttatttagaatatccagtgcgtttctacaaaaaggacatgtaaacttgacaaaaattgtcactttgttattggccaacctttgttgtacaaattcctcggccatttttaatatttaagtgatacaaaactatctcgacttatttaactctttagtcgagatatatggacacagatagctatatgataaccaactacagaagacaaacgctataaaaaacataattacgacgagcatatttataaatatttttattcagtattacttgatatagtaatattaggcacagtcaaacattcaaccactctagatacattaactctctcattttctttaacaaattctgcaatatcttcgtaaaaagattcttgaaactttttagaatatctatcgactctagatgaaatagcgttcgtcaacatactatgttttgtatacataaaggcgcccattttaacagtttctagtgacaaaatgctagcgatcctaggatcctttagaatcacatagattgacgattcgtctctcttagtaactctagtaaaataatcatacaatctagtacgcgaaataatattatccttgacttgaggagatctaaacaatctagttttgagaacatcgataagttcatcgggaattacatacatactatctttaatagaactcttttcatccagttgaatggattcgtccttaaccaactgattaatgagatcttctattttatcattttctagatgatatgtatgtccattaaagttaaattgtgtagcgcttctttttagcctagcagccaatactttaacatcactaatatcgatatacaaaggagatgatttatcgatggtattaagaattcgtttttcgacatccgtcaaaaccaattcctttttgcctgtatcatccagtttgccattctttgtaaagaaattattttctactagactattaataagactgataaggattcctccataattgcacaatccaaactttttcacaaaactagactttacgagatctacaggaatgcgtacttcaggtttcttagcttgtgattttttcttttgtggacattttctagtgaccaactcatctaccatttcattgattttagcagtgaaataagctttcaatgcacgggcactgatactattgaaaacgagttgatcttcaaattccgccatttaagttcaccaaacaacttttaaatacaaatatatcaatagtagtagaataagaactataaaaaaaataataattaaccaataccaaccccaacaacctgtattattagttgatgtgacagttttctcatcacttagaacagatttaacaatttctataaagtctgtcaaatcatcttcctgagaacccataaatacaccaaatatagcagcgtacaacttatccatttatacattgaatattggcttttctttatcgctatcttcatcatattcatcatcaatatcaacaagtcccagattacgaaccagatcttcttctacattttcagtcattgatacgcgttcactatctccagagagtccgataacgttagccactacttctctatcaatgattagtttcttgagcgcgaatgtaatttttgtttccgttccggatctatagaaaactacaggtgtaataattgccttggctaattgtctttctcttttactgagtgattctagttcaccttctatagatctgagaatggatgattctccagtcgaaacatattctaccatggctccgtttaatttgttgatgaagatggattcatccttaaatgttttctctgtaatagtttccgccgaaagactatgcaaagaatttggaatgcgttccttgtgtgtaatgtttccatagacagcttctagaagttgatacaacataggactagccgcggtaacttttatttttagaaagtatccatcgcttctatcttgtttagatttatttttataaagtttagtctctccttccaacataataaaagtggaagtcatctgactagataaactatcagtaagttttatagagatagatgaacaattagcgtattgagaagcatttagtgtaacgcattcgatacattttgcattagatttactaatcgattttgcatactctataacacccgcacaagtctgtagagaatcgctagatgctgtaggtcttggtgaagtttcaactctcttcttgattaccttactcatgattaaacctaaataattgtactttgtaatataatgatatatattttcactttatctcatttgagaataaaaatgtttttgttaaccactgcatgatgtacagatttcggaatcgcaaaccacttgtggttttattttatccttgtccaatgtgaattgaatgggagcggatgcgggtttcgtacgtagatagtacattcccgtttttagaccgagactccatccgtaaaaatgcatactcgttagtttggaataactcggatctgctatatggatattcatagattgactttgatcgatgaaggctcccctgtctgcagccatttttatgatcgtcttttgtggaatttcccaaatagttttataaactcgcttaatatcttctggaaggtttgtattctgaatggatccaccatctaccataatcctattcttgatctcatcattccataattttctctcggttaaaactctaaggagatgcgggttaactacttggaattctccagacaatactctccgagtgtaaatattactggtatacggttccaccgactcattatttcccaaaatttgagcagttgatgcagtcggcataggtgccaccaataaactatttctaagaccgtatgttctgattttatcttttagaggttcccaattccaaagatccgacggtacaacattccaaagatcatattgtagaataccgttactggcgtacgatcctacatatgtatcatatggtccttccttctcagctagtttacaactcgcctctaatgcaccgtaataaatggtttcaaagatcttcttatttagatcttgtgcttccaggctatcaaatggataatttaagagaataaacgcgtccgctaatccttgaacaccaataccgataggtctatgtctcttattagagatttcagcttctggaataggataataattaatatctataattttattgagatttctgacaattactttgaccacatccttcagtttgagaaaatcaaatcgcccatctattacaaacatgttcaatgcaacagatgccagattacacacggctacctcattagcatccgcatattgtattatctcagtgcaaagattactacacttgatggttcctaaattttgttgattactctttttgttacacgcatccttataaagaatgaatggagtaccagtttcaatctgagattctataatcgctttccagacgactcgagcctttattatacatttgtatctcctttctctttcgtatagtgtatacaatcgttcgaactcgtctccccaaacattgtccaatccaggacattcatccggacacatcaacgaccactctccgtcatccttcactcgtttcataaagagatcaggaatccaaagagctataaatagatctcttgttctatgttcatcgtttcctgtattctttttaagatcgaggaacgccataatatcagaatgccacggttccaagtatatggccataactccaggccgtttgtttcctccctgatctatgtatctagcggtgttattataaactctcaacattggaataataccgtttgatataccattggtaccggagatatagcttccactggcacgaatattactaattgatagacctattccccctgccattttagagattaatgcgcatcgttttaacgtgtcatagatgccttctatgctatcatcgatcatgttaagtagaaaacagctagacatttggtgacgagtagttcccgcattaaataaggtaggagaagcgtgcgtaaaccatttttcagaaagtagattgtacgtctcaatagctgagtctatatcccattgatgaattcctactgcgacacgcattaacatgtgctgaggtctttcaacaattttgttgtttattttcaacaagtaggatttttccaaagttttaaaaccaaaatagttgtatgaaaagtctcgttcgtaaataataaccgaattgagcttatccttatatttgttaactatatccatggtaatacttgaaataatcggagaatgtttcccatttttaggattaacatagttgaataaatcctccatcacttcactaaatagtttttttgtttccttgtgtagatttgatatggctattctggcggctagaatggcataatccggatgttgtgtagtacaagtggctgctatttcggctgccagagtgtccaattctaccgttgttactccattatatattccttgaataaccttcatagctattttaataggatctatatgatcagtgtttaagccatagcacaattttctaatacgagacgtgattttatcaaacatgacattttccttgtatccatttcgtttaatgacaaacatttttgttggtgtaataaaaaaaattatttaatttttcattaatagggatttgacgtatgtagcgtacaaaattatcgttcctggtatatagataaagagtcctatatatttgaaaatcgttacggttcgattaaactttaatgattgcattgtgaatatatcattaggatttaactccttgactatcatggcggtgccagaaattaccatcaaaagcattaatacagttatgcagatcgcagttagaacggttatagcatccaccatttatatctaaaaattagatcaaagaatatgtgacaacgtcctagttgtatactgagaattgacgaaacaatgtttcttacatatttttttcttattagtaaccgacttaatagtaggaactggaaaactagacttgattattctataagtatagatacccttccaaataatgttctctttgataaaagttccagaaaatgtagaattttttaaaaagttatcttttgctattactaatatcgtggttagacgcttattattaatatgagtgatgaaatccacaccgcttctagatatcgcttttatttccacattagatggtaaatccaatagtgaaactatctttttaggaatgtatggactcgcgtttagaggagtgaacgtcttcggagtagtaaaggatgattcgtcaaatgaataaacaatttcacaaatggatgttaatgtattagtaggaaattttttgacgctagtggaattgaagattctaatggatgatgttctacctatttcatccgataacatgttaatttccaataccaacggttttaatatttcgatgatatacggtagtctctctttcggacttatatagcttattccacaatacgagtcattatatactccaaaaaacaaaataactagtataaaatctgtatcgaatgggaaaaacgaaattatcgatataggtatagaatccggaacattgaacgtattaatacttaattctttttcagtggtaagaaccgataggttattgacattgtatggttttaaatattctataacttgagacttgatagatattaatgacgaattgaaaattatttttatcaccacgtgtgtttcaggatcatcgtcgacgccagttaaccaaccgaatggagtaaaataaatatcattaatatatgctctagatattagtatttttattaatcctttgattatcatcttctcgtacgcgaatgattccatgatcaagagtgatttgagaacatcctccggagtattaatgggtttagtaaacagtccatcgttgcaataataaaagttgtccaagttaaaggatattatgcattcgtttaaagatatcacctcatctaacggagacaattttttggtaggttttagagactttgaagctacttgtttaacaaagttattcatcgtcgtctactattctatttaattttgtagttaatttatcacatatcacattaattgactttttggtccacttttccatacgtttatattcttttaatcctgcgttatccgtttccgttatatacagggatagatcttgcaagttaaatagaatgctcttaaataatgtcatttttttatccgctaaaaatttaaagaatgtataaacttttttcaaagatttaaaacttttaggtggagttctggtacacaatatcataaacaaactaataaacatcccacattcagattccaacaattgattaacttccacattaatacagcctattttcgctccaaatgtacattcgaaaaatctgaataaaacatcaatatcgcaatttgtattatccaatacagaatgtctgtgattcgtgttaaaaccatcggaaaaagaatagaaataaaaattattataatggtggaattcagttggaatattgcctccggagtcataaaaggatactaaacattgttttttatcgtaaattacacatttccaatgagacaaataacaaaatccaaacattacaaatctagaggtagaacttttaattttgtctttaagtatatacgataagatatgtttattcataaacgcgtcaaatttttcatgaatagctaaggagtttaagaatctcatgtcaaattgtcctatataatccacttcggatccataagcaaactgagagactaagttcttaatacttcgattgctcatccaggctcctctctcaggctctattttcatcttgacgacctttggattttcaccagtatgtattcctttacgtgataaatcatcaattttcaaatccatttgtgagaagtctatcgccttagatactttttcccgtagttgaggtttaaagaaatacgctaacggtatactagtaggtaactcaaagacatcatatatagaatggtaacgcgtcgttaactcgtcggttaactctttcttttgatcgagttcatcgctactattgggtctgctcaggtgccccgactctactagttccaacatcataccgataggaatacaagacactttgccagcggttgtagatttatcatatttctccaccacatatccgttacaatttgttaagaatttagatacatctatattgctacataatccagctagtgaatatatatgacataataaattggtaaatcctagttctggtattttactaattactaaatctgtatatctttccatttatcatggaaaagaatttaccagatatcttcttttttccaaactgcgttaatgtattctcttacaaatattcacaagatgaattcagtaatatgagtaaaacggaacgtgataatttctcattggctgtgtttccagtgataaaacatagatggcataacgcacacgttgtaaaacataaaggaatatacaaagttagtacagaagcacgtggaaaaaaagtatctcctccatcactaggaaaacccgcacatataaacctaatgtcgaagcaatatatatatagtgagtatgcaataagctttgaatgttatagttttctaaaatgtataacaaatacagaaatcaattcgttcgatgagtatatattaagaggactattagaagctggtaatagtttacagatattttccaattccgtaggtaaacgaatagatactataggtgtactagggaataagtatccatttagcaaaattccattggcctcattaactcctaaagcacaacgagagatatttttagcgtggatttctcatagacctgtagttttaactggaggaaccggagtgggtaagacgtcacaggtacccaagttattgctttggtttaattatttatttggtggattctcttctctagataaaatcactgactttcacgaaagaccagtcattctatctcttcctaggatagctttagttagattgcatagcaataccattttaaaatcattgggatttaaggtactagatggatctcctatctctttacggtacggatctataccggaagaattaataaacaaacaaccaaaaaaatatggaattgtattttctacccataagttatctctaacaaaactatttagttatggcactattattatagacgaagttcatgagcatgatcaaataggagatattattatagcagtagcgagaaaacatcatacgaaaatagattctatgtttttaatgactgccacgttagaggatgacagggaacgtctaaaaatatttttacctaatcccgcatttatacatattcctggagatacactgtttaaaattagcgaggtatttattcataataagataaatccatcttccagaatggcatatatagaagaagaaaagagaaatttagttactgctatacagatgtatactcctcctgatggatcatccggtatagtctttgtggcatccgttgcacagtgtcacgaatataaatcatatttagaaaaaagattaccgtatgatatgtatattattcatggtaaggtcttagatatagacgaaatattagaaaaagtgtattcatcacctaatgtatcgataattatttctactccttatttggaatccagcgttactatacgcaatgttacacacatttatgatatgggtagagtttttgtccccgctccttttggaggatcacaacaatttatttctaaatctatgagagatcaacgaaaaggaagagtaggaagagttaatcctggaacatacgtatatttctatgatctgtcttatatgaaatctatacagcgaatagattcagaatttctacataattatatattgtacgctaataagtttaatctaacactccccgaagatttgtttataatccctacaaatttggatattctatggcgtacaaaggaatatatagactcgttcgatattagtacagaaacatggaataaattattatccaattattatatgaagatgatagagtatgctaaactttatgtactaagtcctattctcgctgaggagttggataactttgagaggacgggagaattaactagtattgtacaagaagccattttatctctaaatttacaaattaagattttaaaatttaaacataaagatgatgatacgtatatacacttttgtagaatattattcggtgtctataacggaacaaacgctactatatattatcatagacctctaacgggatatatgaatatgatttcagatactatatttgttcctgtagataataactaaaaatcaaaatctaatgaccacatctttttttagagatgaaaaattttccacatctccttttgtagacacgactaaacattttgcagaaaaaagtttattattatttagataatcgtatacttcatcagtgtagatagtaaatgtgaacagataaaaggtattcttgctcaatagattggtaaattccatagaatatattaatcctttcttcttgagatcccacatcatttcaaccaaagacgttttatccaatgatttacctcgtactataccacatacaaaactagattttgcagtgatgtcgtacctggtattcctaccaaacaaaattttacttttagttcttttagaaaattctaaggtagaatctctatttgtcaatatgtcatctatggaattaccactagcaaaaaatgatagaaatatatattgatacatcgcagctggttttgatctactatactttaaaaacgaatcagattccataattgcttgtatatcatcagctgaaaaactatgttttacacgtattccttcggcatttctttttaatgatatatcttgtttagacaatgataaagttatcatgtccatgagagacgcgtctccgtatcgtataaatatttcattagatgttagacgcttcattaggggtatacttctataaggtttcttaattagtccatcattggttgcgtcaagaactactatctgatgttgttgggtatctctagtgttacacatggccttactaaagtttgggtaaataactatgatatctctattaattatagatgtatatatttcattcgtcaaggatattaatatcgacttactatcgtcattaatacgtgtaatgtaatcatataaatcatgcgatagccaaggaaaattcaaatagatgttcatcatataatcgtcgctataattcatattaatactttgacattgactaatttgtaatatagcctcgccacgaagaaagctctcgtattcagtttcatcgataaaggataccgttaaatataactggttgccgatagtctcatagtctattaagtggtaagtttcgtataaatacagaatccctaaaatattatctaatgtgggattaatccttaccataactgtataaaatggagccggagtcataactattttaccgtttgtacttactggaatagatgaaggaataatctccggacatgatggtaaagacccaaatgtctgtttgaagaaatccaatgttccaggtcctaatctcttgacaaaaattacgatattcgatcccgatatcctttgcattctatttaccagcatatcacgaactatattaagattatctatcatgtctattctcccaccgttatataaatcgcctccgctaagaaacgttagtatatccatacaatggaatacttcatttctaaaatagtattcgttttctaattctttaatgtgaaatcgtatactagaaagggaaaaattatctttgagttttccattagaaaagaaccacgaaactaatgttctgattgcgtctgactccgtcgctgaattaatagatttacaccaaaaactcatataacttctagatgtagaagcattcgctaaaaaattagtagaatcaaaggatataagtagatgttccaacaagtgagcaattcccaagatttcatctatatcattctcgaatccgaaattagaaattcccaagtagatatcctttttcatccgatcattgatgaaaatacgaactttattcggtaagacgatcatttactaaggagtaaaataggaagtaacgttcgtatatcgttatcgtcgtataaattaaaggtgtgttttttgccattaagagacattataattttaccaatattggaattataatataggtgtatttgagcactagaaacggtcgatgcatcggtaaatatagctgtatctaatgttctagtcggtatttcttcatttcgctgtctaatgatagcgttttctctatctgtttccattacagctgcctgaagtttattggtcggataatatgtaaaataataagaaatacatacgaataacaaaaataaaataagatataataaagatgccatttagagatctaattttgttcaacttgtccaaattcctacttacagaagatgaggaatcgttggagatagtatcttccttatgtagaggatttgaaatatcttacgatgacttaatatcgtactttccagataggaaataccataaatatatttctaaggtatttgaacatgtagatttatcggaggaattaagtatggaattccatgatacaactctgagagatttagtatatcttagattgtacaagtattccaagtatatacggccgtgttataaattaggagataatctaaaaggtatagttgttataaaggacagaaatatatatattagagaagcaaatgatgacttgatagaatatctcctcaaggaatacactcctcagatttatacatattctaatgagcgagttcccatagctggttcaaaattaattctttgtggattttctcaagttacatttatggcgtatacaacgtcgcatataacaacaaataaaaaggtagatgttctcgtttccaaaaaatgtatagatgaactagtcgatccaataaattatcaaatacttcaaaatttatttgataaaggaagcggaacaataaacaaaatactcaggaagatattttattcggtaacaggtggccaaactccataggtagctttttctatttcggattttagaatttccaaattcaccagcgatttatcggttttggtgaaatccaaggatttattaatgtccacaaatgccatttgttttgtctgtggattgtatttgaaaatggaaacgatgtagttagatagatgcgcggcgaagtttcctattagggttccgcgcttcacgtcacccaacatacttgaatcaccatcctttaaaaaaaatgataagatatcaacatggagtatatcatactcggattttaattcttctactgcctcactgacattttcacaaatactacaatacggtttaccgaaaataatcagtacgttcttcatttatgggtatcaaaaacttaaaatcgttactgctggaaaataaatcactgacgatattagatgataatttatacaaagtatacaatggaatatttgtggatacaatgagtatttatatagccgtcgccaattgtgtcagaaacttagaagagttaactacggtattcataaaatacgtaaacggatgggtaaaaaagggaggacatgtaaccctttttatcgatagaggaagtataaaaattaaacaagacgttagagacaagagacgtaaatattctaaattaaccaaggacagaaaaatgttagaattagaaaagtgtacatccgaaatacaaaatgttaccggatttatggaagaagaaataaaggcagaaatgcaattaaaaatcgataaactcacatttcaaatatatttatctgattatgataacataaaaatatcattgaatgagatactaacacatttcaacaataatgagaatgttacattattttattgtgatgaacgagacgcagaattcgttatgtgtctagaggctaaaacacagttctctaccacaggagaatggccgttaataataagtaccgatcaggatactatgctattcgcgtctgctgataatcatcctaagatgataaaaaacttaactcaactgtttaaatttgttccctcggcagaggataactatttagcaaaattaactgcattagtgaatggatgtgatttctttcctggactctatggggcatctataacacccaacaacttaaacaaaatacaattgtttagtgattttacaatcgataatatagtcactagtttggcaattaaaaattattatagaaagactaactctaccgtagacgtgcgtaatattgttacgtttataaacgattacgctaatttagacgatgtctactcgtatattcctccttgtcaatgcactgttcaagaatttatattctccgcattagatgaaaaatggaatgaatttaaatcatcttatttagagagcgtgccgttaccctgccaattaatgtacgcattagaaccacgtaaggagattgatgtttcagaagttaaaactttatcatcttatatagatttcgaaaatactaaatcagatatcgatgttataaaatctatatcctcgatttttggatattctaacgaaaactgtaacaccatagtgttcggcatctataaggataatttactactgagtataaataattcattttactttaacgatagtctgttaataaccaatactaaaagtgataatataataaatataggttactagattaaaaaatggtgttccagctcgtgtgttctacatgcggcaaagatatttctcacgaacgatataaattgattatacgaaaaaaatcattaaaggatgtactagtcagtgtaaagaacgaatgttgtaggttaaaattatctacacaaatagaacctcaacgtaacttaacagtgcaacctctattggatataaactaatggatccggttaattttatcaagacatatgcgcctagaggttctattatttttattaattatgccatgtcattaactagtcatttgaatccatcgatagaaaaacatgtgggtatttattatggtacgttattatcggaacacttggtagttgaatctacctatagaaaaggagttagaatagtcccattggatagattttttgaaggatatcttagtgcaaaagtatacatgttagagaatattcaagttatgaaaatagcagctgatatgtcgttaactttactaggtattccatatggatttggtcatgatagaatgtattgttttaaattggtagctgaatgttataaaaatgccggtattgatacatcgtctaaacgaatattaggtaaagatatttttctgagccaaaactttacagatgataatagatggataaagatatatgattctaataatttaacattttggcaaattgattaccttaaagggtgagttaatatgcataactactcctccgttgttttttccctcgttctttttcttaacgttgtttgccatcactctcataatgtaaagatattctaaaatggtaaacttttgcatatcggatgcagaaattggtataaatgttgtaattgtattatttcccgtcaatggactagtcacagctccatcagttttatatcctttagagtatttctcactcgtgtctagcattctagagcattccatgatctgtttatcgttgatattggccggaaagatagattttttattttttattatattactattggcaattgtagatataacttctggtaaatatttttctaccttttcaatctcttctattttcaagccggctatatattctgctatattgttactagtatcaataccttttctggctaagaagtcatatgtggtattcactatatcagttttaactggtagttccattagcctttccacttctgcagaataattagaaattggttctttaccagaaaatccagctactataataggctcaccgatgatcattggcaaaatcctatattgtaccagattaatgagagcatatttcatttccaataattctgctagttcttgagacattgatttatttgatgaatctatttggttctctagatactctaccatttctgccgcatacaataacttgttagataaaatcagggttatcaaagtgtttagtgtggctagaatagtgggcttgcacgtattaaagaatgctgtagtatgagtaaaccgttttaacgaattatatagtctccagaaatctgtggcgttgcatacatgaactgaatgacatcgaagattgtccaatatttttaatagctgctctttgtccattatttctatatttgactcgcaacaattgtagataccattaatcactgattcctttttcgatgccggacaatagcacaattgtttagctttggactctatgtattcagaattaatagatatatctctcaatacagattgcactatacattttgaaactatgtcaaaaattgtagaacgacgctgttctgtagccatttaactttaaataatttacaaaaatttaaaatgagcatccgtataaaaatcgataaattgcgccaaattgtggcatatttttcagagttcagcgaagaagtgtctataaatgtagacttgacggatgaattaatgtatatttttgccgccttgggcggatctgtaaacatttgggccattatacctctcagtgcatcagtgttctaccgcggagccgaaaatattgtgtttaaccttccagtgtccaaggtaaaatcgtgtttgtgtagttttcacaatgatgctatcataaatatagaacctgatctggaaaataatctagtaaaactttctagttatcatgtagtaagtgtcgattgtaacaaggaactgatgcctattaggacagatactactatttgtctaagtatagatcaaaagaaatcttacgtatttaattttcacaagtatgaagaaaaatgttgtggtagaaccgtcattcatctagaatggttgttgggctttatcaagtgtattagtcagcatcagcatttggctattatgtttaaagatgacaatattattatgaagactcctggtaatactgatgcgttttccagggaatattctatgactgaatgttctcaagaactacaaaagttttctttcaaaatagctatctcgtctctcaacaaactacgaggattcaaaaagagagtcaatgtttttgaaactagaatcgtaatggataatgacgataacattctaggaatgttgttttcggatagagttcaatcctttaagattaacatctttatggcgtttttagactaatactttcaatgagataaatatgggtggcggagtaagtgttgagctccctaaacgggatccacctccgggagtacccactgatgagatgttattaaacgtggataaaatgcatgacgtgatagctcccgctaagcttttagaatatgtgcatataggaccactaacaaaagataaagaggataaagtaaagaaaagatatccagagtttagattagtcaacacaggacccggtggtctttcggcattattaagacaatcatataatggaaccgcacccaattgctgtcgcacttttaatcgtactcattattggaagaaggatggaaagatatcagataagtatgaagagggtgcagtattagaatcgtgttggcccgacgtccacgacactggaaaatgcgatgttgatttattcgactggtgtcagggggatacgttcgatataaacatatgccatcagtggatcggttcagcctttaataggagtgatagaactgtagagggtcgacaatcgttaataaatctgtataataagatgcaaagattatgtagtaaagatgctagtgtaccaatatgtgaattatttttgcatcatttacgcgcacacaatacagaagatagtaaagagatgatcgattatattctaagacaacagtcggcggactttaaacagaaatatatgagatgtagttatcccactagagataagttagaagagtcattaaaatatgcggaacctcgagaatgttgggatccagagtgttcgaatgccaatgttaatttcttactaacacgtaattataataatttaggactttgcaatattgtacgatgtaatacgagcgtgaataacttacagatggataaaacttcctcattaagattatcatgtggattaagcaatagtgatagattttctactgttcccgtcaatagagcaaaagtagttcaacataatattaaacattcgttcgacctaaaattgcatttgatcagtttattatctctcttggtaatatggatactaattgtagctatttaaatgggtgccgcagcaagcatacagacgactgtgaatacactcagtgaacgtatctcgtctaaattagaacaagaagcgaacgctagtgctcaaacaaaatgtgatatagaaatcggaaatttttatatccgacaaaaccatggatgtaacatcactgttaaaaatatgtgctctgcggacgcggatgctcagttggatgctgtgttatcagccgctacagaaacatatagtggattaacaccggaacaaaaagcatacgtaccagctatgtttactgctgcgttaaacattcagacgagtgtaaacactgttgttagagattttgaaaattatgtgaaacagacttgtaattctagcgctgttgtcgataacaaattaaagatacaaaacgtaattatagatgaatgttacggagccccaggatctccaacaaatttggaatttattaatacaggatctagcaaaggaaattgtgccattaaggcgttgatgcaattgactactaaggccactactcaaatagcacctagacaagttgctggtacaggagttcagttttatatgattgttatcggtgttataatattggcagcgttgtttatgtactatgccaagcgtatgctgttcacatccaccaatgataaaatcaaacttattttagccaataaggaaaacgtccattggactacttacatggacacattctttagaacttctccgatgattattgctaccacggatatacaaaactgaaaatatattgataatattttaatagattaacatggaagttatcgctgatcgtctagacgatatagtgaaacaaaatatagcggatgaaaaatttgtagattttgttatacacggtctagagcatcaatgtcctgctatacttcgaccattaattaggttgtttattgatatactattatttgttatagtaatttatatttttacggtacgtctagtaagtagaaattatcaaatattgttggtgttggtggcgctagtcatcacattaactatttttttattactttatactataatagtactagactgacttctaacaaacatctcacctgccataaataaatgcttgatattaaagtcttctatttctaacactattccatctgtggaaaataatactctgacattatcgctaattgatacatcggtaagtgatatgcctataaagtaataatcttctttgggcacatataccagtgtaccaggttctaacaacctatttactggtgctcctgtagcatactttttttttaccttgagaatatccattgtttgcttggtcaatagtgatatgtgattttttatcaaccactcaaaaaagtaattggagtgttcatatcctctacgggctattgtctcatgaccgtgtatgaaatttaagtaacacgactgtggtagatttgttctatagagccggttgccgcaaatagatagaactaccaatatgtctgtacaaatgttaaacattaattgattaacagaaaaaacaatgttcgttctgggaatagaaaccagattaaaacaaaattcattagaatatatgccacgtttatacatggaatataaaataactacagtttgaaaaataacagtatcatttaaacatttaacttgcggggttaatctcacaactttactgtttttgaactgttcaaaatatagcatagatccatgagaaatacgtttagccgcctttaatagaggaaatccaaccgcctttctggatctcaccaacgacgatagttctgaccagcaactcatttcttcatcatccacctgttttaacatataataggcaggagatagatatccatcattgcaatattccttctcgtaggcacacaatctaatattgataaaatctccattctcttctctgtatttattatcttgtctcggtggctgattaggctgtggtctatcgttgttgaatctattttggtcattaaatctttcatttcttcctggtatatttctatcacctcgtttggttggatttttgtctatattatcgtttgtaacatcggtacgggtattcatttatcacaaaaaaaacttctctaaatgagtctactactagaaaacctcatcgaagaagataccatattttttgcaggaagtatatctgagtatgatgatttacaaatggttattgctggtgcaaaatccaaatttccaagatctatgctttctatttttaatatagtacctagaacgatgtcaaaatatgagttggagttgattcataacgagaatatcacaggggcaatgtttaccacaatgtataatataagaaacaatttgggtctaggcgatgataaactaactattgaagccattgaaaactatttcttggatcctaacaatgaggttatgcctcttatcattaataatacggatatgactaccgtcattcctaaaaaaagtggtaggagaaagaataagaacatggttatcttccgtcaaggatcatcacctatcttgtgtattttcgaaactcgtaaaaagattaatatttataaagaaaatatggaatccgtatcgactaagtatacacctatcggagacaacaaggctttgatatctaaatatgcgggaattaatatcctgaatgtgtattctccttccacgtccatgagattgaatgccatttacggattcaccaataaaaataaactagagaaacttagtactaataaggaactagaatcgtatagttctagccctcttcaagaacccattaggttaaatgattttctgggactattggaatgtgttaaaaagaatattcctctaacagatattccgacaaaggattgattactataaatggagaatgttcctaatgtatactttaatcctgtgtttatagagcccacgtttaaacattctttattaagtgtttataaacacagattaatagttttatttgaagtattcgttgtattcattctaatatatgtattttttagatctgaattaaatatgttcttcatgcctaaacgaaaaatacccgatcctattgatagattacgacgtgctaatctagcgtgtgaagacgataaattaatgatctatggattaccatggataacaactcaaacatctgcgttatcaataaatagtaaaccgatagtgtataaagattgtgcaaagcttttgcgatcaataaatggatcacaaccagtatctcttaacgatgttcttcgcagatgatgattcattttttaagtattttgctagtcaagatgatgaatcttcattatctgatatattgcaaatcactcaatatctagactttctgttattattattgatccaatcaaaaaataaattagaagctgtgggtcattgttatgaatctctttcagaggaatacagacaattgacaaaattcacagactctcaagattttaaaaaactgtttaacaaggtccctattgttacagatggaagggtcaaacttaataaaggatatttgttcgactttgtgattagtttgatgcgattcaaaaaagaatcagctctagctaccaccgcaatagatcctgttagatacatagatcctcgtcgtgatatcgcattttctaacgtgatggatatattaaagtcgaataaagttgaaaaataattaattctttattgttatcatgaacggcggacatattcagttgataatcggccccatgttttcaggtaaaagtacagaattaattagacgagttagacgttatcaaatagctcaatataaatgtgtgactataaaatattctaacgataatagatacggaacgggactatggacacatgataagaataattttgcagcattggaagtaactaaactatgtgatgtcttggaagcaattacagatttctccgtgataggtatagatgaaggacagttctttccagacattgttgaattctgtgagcgtatggcaaacgaaggaaaaatagttatagtagccgcgctcgatgggacatttcaacgtagaccgtttaataatattttgaatcttattccattatctgaaatggtggtaaaactaactgcagtgtgtatgaaatgctttaaggaggcttccttttctaaacgattaggtacagaaaccgagatagaaataataggaggtaatgatatgtatcaatctgtgtgtagaaagtgttacatcgactcataatattatattttttatctaaaaaactaaaaataaacattgattaaattttaatataatacttaaaaatggatgttgtgtcgttagataaaccgtttatgtattttgaggaaattgataatgagttagattacgaaccagaaagtgcaaatgaggtcgcaaaaaaactgccgtatcaaggacagttaaaactattactaggagaattattttttcttagtaagttacagcgacacggtatattagatggcgccaccgtagtgtatataggatctgctccaggtacacatatacgttatttgagagatcatttctataatttaggagtgatcatcaaatggatgctaattgacggccgccatcatgatcctattctaaatggattgcgtgatgtgactctagtgactcggtttgttgatgaggaatatctacgatccatcaaaaaacaactacatccttctaagattattttaatttctgatgtgcgatccaaacgaggaggaaatgaacctagtactgcggatttactaagtaattatgctctacaaaatgtcatgattagtattttaaaccccgtggcgtctagtcttaaatggagatgcccgtttccagatcaatggatcaaggacttttatatcccacacggtaataaaatgttacaaccttttgctccttcatattcagctgaaatgagattattaagtatttataccggtgagaatatgagactgactcgagttaccaaatcagacgctgtaaattatgaaaaaaagatgtattaccttaataagatagtccgcaacaaagtagttattaactttgattatcctaatcaggaatatgactattttcacatgtactttatgttgaggaccgtatactgcaataaaacatttcctactactaaagcaaagatactatttctacaacaatctatatttcgtttcttaaatattccaacgacatcaactgaaaaagttagtcatgaaccaatacaacgtaaaatatctagcaaagattctatgtctaaaaacagaaatagcaagagatccgtacgcggtaataaatagaaacgtactactgagatatactaccgatatagagtataatgatttagttactttaataaccgttagacataaaattgattctatgaaaactgtgtttcaggtatttaacgaatcatccataaattatactccggttgatgatgattatggagaaccaatcattataacatcgtatcttcaaaaaggtcataacaagtttcctgtaaattttctatacatagatgtggtaatatctgacttatttcctagctttgttagactagatactacagaaactaatatagttaatagtgtactacaaacaggcgatggtaaaaagactcttcgtcttcctaaaatgttagagacggaaatagttgtcaagattctctatcgtcctaatataccattaaaaattgttagatttttccgcaataacatggtaactggagtagagatagccgatagatctgttatttcagtcgctgattaatcaattagtagagatgagataagaacattataataatcaataatatatcttatatctgtttagaaaaatgctaatattaaaatagctaacgctagtaatccaatcggaagccatttgatatctataatagggtatctaatttcctgattcagatagcgtacggctatattctcggtagctactcgtttggaatcacagacattatttacatctaatttactatctgtaatggaaacgtttcccaatgaaatggtacaatcagatacattacatcttgatatatttttttttaaagaggctggtaacaacgcatcgcttcgtttacatggctcgtaccaacaataatagggtaatcttgtatctattcctatccgtactatacttttatcaggataaatacatttacatcgtatatcgtctttgttagtatcacagaatgcataaatttgttcgtccgtcatgataaaaatttaaagtgtaaatataactattatttttatagttataataaaaagggaaatttgattgtataccttcggttctttaaaagaaactgacttgataaaaatggctgtaatctctaaggttacgtatagtctatacgatcaaaaagagattaatgccacagatattatcattagtcatattaaaaatgacgacgatatcggtaccgttaaagatggtagactaggtgctatggatggggcattatgtaaaacttgtgggaaaacggaattggaatgtttcggtcactggggtaaagtaagtatttataaaactcatatagttaagcctgaatttatttcagaaattattcgtttactgaatcatatatgtattcattgcggattattgcgttcacgagaaccgtattccgacgatattaacctaaaagagttatcggtacacgctcttaggagattaaaggataaaatattatccaagaaaaagtcatgttggaacagcgaatgtatgcaaccgtatcaaaaaattactttttcaaagaaaaaggtttgtttcgtcaacaagttggatgatattaacgttcctaattctctcatctatcaaaagttaatttctattcatgaaaagttttggccattattagaaattcatcaatatccagctaacttattttatacagactactttcccatccctccgttgattattagaccggctattagtttttggatagatagtatacccaaagagacaaatgaattaacttacttattaggtatgatcgttaagaattgtaacttgaatgctgatgaacaggttatccagaaggcggtaatagaatacgatgatattaaaattatttctaataacactaccagtatcaatttatcatatatcacatccggcaaaaataatatgattagaagttatatcgtcgctcggcgaaaagatcagaccgctagatccgtaattggtcccagtacatctatcaccgttaatgaggtaggaatgcccacatatattagaaatacacttacagaaaagatatttgttaatgcctttacagtggataaagttaaacaactattagcatcaaaccaagttaaattttactttaataaacgattaaaccaattaacaagaatacgtcaaggaaagtttatcaaaaataaaatacatttattgcctggtgattgggtagaagtagctgttcaagaatatacaagtattatttttggaagacaaccgtctctacatagatacaacgtcatcgcttcatctatcagagctaccgaaggagatactatcaaaatatctcccggaattgccaactctcaaaatgctgattttgacggagatgaagaatggatgatattggagcaaaatcctaaagccgtagttgaacaaagtattcttatgtatccgacaacgttactcaaacacgatattcatggagcccccgtttatggatctattcaagatgaaatcgtagcagcgtattcattgtttaggatacaagatctttgtttagatgaagtattgaacatcttggggaaatatggaagagagttcgatcctaaaggtaaatgtaaattcagcggtaaagatatctatacttacttgataggtgaaaagattaattatccgggtctcttaaaggatggtgaaattattgcaaacgacgtagatagtaattttgttgtagctatgaggcatctgtcattggctggactcttatccgatcataaatcgaacgtggaaggtatcaactttattatcaagtcatcttatgtttttaagagatatctatctatatacggttttggggtgacattcaaagatctgagaccaaattcgacgttcactaataaattggaggctatcaacgtagaaaaaatagaacttatcaaagaagcatacgccaaatatctcaaagatgtaagagacgggaaaatagttccattatctaaagctttagaggcggactacttggaatccatgttatccaacttgacaaatcttaatatcagagagatagaagaacatatgagacaaacgctgatagatgatccagataataacctcctgaaaatggccaaagcgggttataaagtaaatcccacagaactaatgtatattctaggtacttatggacaacagaggatagatggcgaaccagcagagactcgagtattgggtagagtcttaccttactatcttccagactctaaggatccagaaggaagaggttatattcttaattctttaacaaaaggattaacgggttctcaatattactttttgatgctggttgcaagatctcaatctactgatattgtctgtgaaacatcacgtaccggaacactggctagaaaaatcattaaaaagatggaggatatggtggtcgacggatacggacaagtagttataggtaatacgctcatcaagtacgcagccaattataccaaaattctaggctcagtatgtaaacctgtagatcttatctatccagatgagtccatgacttggtatttggaaattagtgctttgtggaataaaataaaacagggattcgtttactctcagaaacagaaacttgcaaagaagacattggcgccgtttaatttcctagtattcgtcaaacccaccactgaggataatgctattaaggttaaggatctgtacgatatgattcataacgtcattgatgatgtgagagagaaatacttctttacggtatctaatatagattttatggagtatatattcttgacgcatcttaatccttctagaattagaattacaaaagaaacggctattactatctttgaaaagttctatgaaaaactcaattatactctaggtggtggaactcctattggaattatttctgcacaggtattgtctgagaagtttacacaacaagccctgtccagttttcacactactgaaaagagtggtgctgtaaaacaaaaacttggtttcaacgagtttaataacttgactaatttgagtaagaataagaccgaaattatcactctggtatccgatgatatctctaaacttcaatctgttaagattaatttcgaatttgtatgtttgggagaattaaatccagacatcactcttcgaaaagaaacagatagatatgtagtagacataatagtcaatagattatacatcaagagagcagaaataaccgaattagtcgtcgaatatatgattgaacgatttatctcctttagcgtcattgtaaaggaatggggtatggagacattcattgaggacgaggataatattagatttactatctacctaaatttcgttgaaccggaggaattgaatcttagtaagtttatgatggttcttccaggtgccgccaacaagggcaagattagtaaattcaagattcctatctctgactatacgggatataacgacttcaatcaaacaaaaaagctcaataagatgactgtagaactcatgaatctaaaagaattgggttctttcgatttggagaacgtcaacgtgtatcctggagtatggaatacatacgatatctttggtattgaggccgctcgtggatacttgtgcgaagccatgttaaacacctatggagaaggtttcgattatctgtaccagccttgtgatcttctcgctagtttactatgtgctagttacgaaccagaatcagttaataaattcaagttcggtgcagctagtactcttaagagagctacgttcggagataataaagcattgttaaacgcggctcttcataaaaagtcagaacctattaacgataatagtagctgccacttttttagcaaggtccctaatataggaactggatattacaaatactttatcgacttgggtcttctcatgagaatggaaaggaaactatctgataagatatcttctcaaaagatcaaggagatagaagaaacagaagacttttaattcttatcaataacatatttttctatgatctgtcttttaaacgatggattttccacaaatgcgcctctcaagtccctcatagaatgatacacgtataaaaaatatagcataggtgatgactccttatttttagacattagatatgccaaaatcatagccccgcttctatttactcctgcaacacaatgaaccaacacgggctcgtttcgttgatcacatttagataagaaggcggtcacgtcgtcaaaatatttactaatatcagtagttgtatcatctaccaacggtatatgaataatattaatattagagttaggtaatgtatatttatccatcgtcaaatttaaaacatatttgaacttaacttcagatgatggtgcatccatagcatttttataatttcccaaatacacattatttgttactcttgtcattatagtgggagatttggctctgtgcatatctccagttgaacgtagtagtaagtatttatacaaacttttcttatccatttataacgtacaaatggataaaactactttatcagtaaacgcatgcaatttagaatacgttagagaaaaggctatagtaggcgtacaagcagccaagacatcaacacttatattttttgttattatattggcaattagtgcgctattactctggtttcagacgtctgataatccagtctttaatgaattaacgagatatatgcgaattaaaaatacggttaacgattggaaatcattaacggatagcaaaacaaaattagaaagcgatagaggtagacttctagccgctggtaaggatgatatattcgaattcaaatgtgtggatttcggcgcctattttatagctatgcgattggataagaaaacatatctgccgcaagctattaggcgaggtactggagacgcgtggatggttaaaaaggcggcaaaagtcgatccatctgctcaacaattttgtcagtatttgataaaacacaagtctaataatgttattacttgtggtaatgagatgttaaatgaattaggttatagcggttattttatgtcaccgcattggtgttccgatcttagtaatatggaataagtgttagataaatgcggtaacaaatgttcctgtaaggaaccataacagtttagatttaacattaaagatgagcataaacataataaacaaaattacaatcaaacctataacattaatatcaaacaatccaaaaaatgaaatcaatggagtagtaaacgtgtacataactcctggataacgtttagcagctaccgttcctattctagaccaaaaatttggtttcatggtttcgaagcggtgttctgcaacaagacgaggatcgtgttctacatatttggcagagttatccattatttgcctgttaatcttcatttcgttttcgattctggctatttcaaaataaaatcccgatgatagacctccagactttataatttcatctacgatgttcagcgccgtagtaactctaataatataggcggataagctaacatcataccctcctgtatatgtaaatatggcatgatctttgtctattacaagctcggttttaactttatttcctgtaataatttctctcatctgtaggatatctattttcttgtcatgtattgccttcaagacgggacgaagaaacgtaatatcctcaataacgttatcgttttctataataactacatattctacatttttattttctagctcggtaaaaaatttagaatcccatagggctaaatgtctagcgatatttcttttcgtttcctctgtacacatagtgttacaaaaccctgaaaagaagtgagtatacttgtcatcatctctaatatttcctccagtccattgtataaacacataatccttgtaatgatctggatcatcattgactatcacaacatctcttttttcttgcataacttcattgtccttcacatcatcgaacttctgatcattaatatgctcatgaacattaggaaatgtttctgatggaggtctatcaataactggcacaacaataacaggagttttcaccgccgccatttagttattgaaattaatcatatacaactctctaatacgagttatattttcgtctatccattgtttcacattgacatatttcgacaaaaagatataaaatgcgtattccaatgcttctctgtttaatgaattactaaaatatacaaacacgtcactgtctggtaataaataatatcttagaatattgtaacaatttattttgtattgcacatgttcgtgatctatgagttcttcttcaaatggcataggatctccgaatctgaaaacgtataaataggagttagaataataatatttgagagtattggtaatgtataaactctttagcggtataattagtttttttctctcgatttctatttttagatgtgatggaaaaatgactaattttgtagcattagtatcatgaactctaatcaaaatcttaatatcttcgtcacatgttagctctttgaagtttttaagagatgcatcagttggttttacagatggagtaggtgcaacaattttttgtttaatgcatgcatgtattggagccattgtcttaactataatggtgcttgtatcgaaaaactttaatgcggataacggaagctcttcgccgcgactttctacgtcgtaattgggttctaatgccgatctctgaatggatactagttttctaagttctaatgtaattctctgaaaatgtaaatccaattcctccggcattatagatgtgtatacatcggtaaataaaactatagtatccaacgatcccttctcgcaaattctagtcttaaccaagaaatcgtatataactacggagatggcgtatttaagagtggattcttctaccgttttgttcttggatttcatataagaaactataaagtccgcactactgttaagaatgatcactaacgcaactatatagttcaaattaagcatcttggaaacataaaataactctgtagatgatacttgactttcgaataagtttgcagacaaacgaagaaagaacagacctctcttaatttcagaagaaaactttttttcgtattcctgacgtctagagtttatatcaataagaaagttaagaattagtcggttaatgttgtatttcattacccaagtttgagatttcataatattgtcaaaagacatgataatattaaagataaagcgctgactatgaacgaaatagctatatggttcgctcaagaatatagtcttgttaaacgtggaaacgataactgtatttttaatcacgtcagcggcatctaaattaaatataggtatatttattccacacactctacaatatgccacaccatcttcataataaataaattcgttagcaaaattattaattttagtgaaatagttagcgtcaactttcatagcttccttcaatctaatttgatgctcacatggcgcgaattctactctaacatcccttttccatgcctcaggttcatcgatctctataatatctagtttcttgcgtttcacaaacacaggctcgtctctcgcgatgagatctgtatagtaactatgtaaatgataactagatagaaagatgtagctatatagatgacgatcctttaagagaggtataataactttaccccaatcagatagactgttgttatggtcttcggaaaaagaatttttataaatttttccagtattttctaaatatacgtacttgatatctaagaaatccttaataataataggaatggataatccgtctattttataaagaaatacatatcgcatattatacttttttttggaaattggaataccgatgtgtctacataaatacgcaaagtctaaatattttttagagaatcttagttggtccaaattcttttccaagtacggtaatagatttttcatattgaacggtatcttcttgatctctggttctaattccgcattaaatgatgaaactaagtcactatttttataactaacgattacatcacctctaacatcatcatttaccaggatactgatcttcttttgtcgtaaatacatgtctaatgtgttaaaaaaaagatcatacaagttatacgtcatttcatctgtagtattcttgtcattgaaggataaactcgtactaatctcttctttaacagtctgttcaaatttatatcctatatatgaaaaaatagcaaccagtgtttgatcatccgcgtcaatattctgttctatcgtagtgtataacaatcttatatcttcttctgtgatagtcgatacgttataaaggttgataacgaaaatatttttatttcgtgaaataaagtcattgtaggattttggacttatattcgtgtctagtagatatgattttatttttggaatgatctcaattaaaatagtctctttagagtccatttaaagttacaaacaactaggaaattggtttatgatgtataatttttttagtttttatagattctttattctatacttaaaaaatgaaaataaatacaaaggttcttgagggttgtgttaattgaaagcgataaataatcataaattatttcattatcgcgatatccgttaagtttgtatcgtaatggcgtggtcaattacgaataaagcggatactagtagtttcacaaagatggctgaaatcagagctcatctaagaaatagcgctgaaaataaagataaaaacgaggatattttcccggaagatgtaataattccatctactaagcccaaaaccaaacgaaccactactcctcgtaaaccagcggctactaaaagatcaaccaaaaaggataaagaaaaggaggaagtggaagaagtagttatagaggaatatcatcaaacaactgaagaaaattctccacctccgtcatcatctcctggagtcggcgacattgtagaaagcgtggccgctgtagagctcgatgatagcgacggggatgatgaacctatggtacaagttgaagctggtaaagtaaatcatagtgctagaagcgatctctctgacctaaaggtggctaccgacaatatcgttaaagatcttaagaaaattattactagaatctctgcagtatcgactgttctagaggatgttcaagcagctggtatctctagacaatttacttctatgactaaagctattacaacactatctgatctagtcaccgagggaaaatctaaagttgttcgtaaaaaagttaaaacttgtaagaagtaaatgcgtgcacttttttataaagatggtaaactgtttaccgataataattttttaaatcctgtatcagacgataatccagcgtatgaggttttgcaacatgttaaaattcctactcatttaacagatgtagtagtatatgaacaaacgtgggaagaggcattaactagattaatttttgtgggaagtgattcaaaaggacgtagacaatacttttacggaaaaatgcatatacagaatcgcaatgctaaaagagatcgtatttttgttagagtatataacgttatgaaacgaattaattgttttataaacaaaaatataaagaaatcgtccacagattccaattatcagttggcggtttttatgttaatggaaactatgttttttattagatttggtaaaatgaaatatcttaaggagaatgaaacagtagggttattaacactaaaaaataaacacatagaaataagtcccgatgaaatagttatcaagtttgtaggaaaggacaaagtttcacatgaatttgttgttcataagtctaatagactatataaaccgctattgaaactgactgatgattctagtcccgaagaatttctgttcaacaaactaagtgaacgaaaggtatatgaatgtatcaaacagtttggtattagaatcaaggatctccgaacgtatggagtcaattatacgtttttatataatttttggacaaatgtaaagtccgtatctcctcttccatcaccaaaaaagttgatagcattaactatcaaacaaactgctgaagtggtaggtcatactccatcaatttcaaaaagagcttatatggcaacgactattttagaaatggtaaaggataaaaattttttagacgtagtatctaaaactacgttcgatgaattcctatctatagtcgtagatcacgttaaatcatctacggatggatgataatagatctttacacaaataattacaagaccgataaatggaaatggataaacggatgaaatctctcgctatgacagctttcttcggagagctaaacacgttagatattatggcattgataatgtctatatttaaacaccatccaaacaataccattttttcagtggataaggatggtcaatttatgattgatttcgaatacgataattataaggcttctcaatatttggatctgaccctcactccgatatctggaaatgaatgcaagactcacgcatctagtatagccgaacaattggcgtgtgtggatattattaaagaggatattagcgaatatatcaaaactactccccgtcttaaacgatttataaaaaaataccgcaatagatcatatactcgtatcagtcgagatacagaaaagcttaaaatagctctagctaaaggcatagattacgaatatataaaagacgcttgttaataagtaaatgaaaaaaaactagtcgtttataataaaacacaatatggatgccaacatagtatcatcttctactattgcgacgtatatagacgctttagcgaagaatgcttcagaattagaacagaggtctaccgcatacgaaataaataatgaattggaactagtatttattaaaccgccattgattacgttgacaaatgtagtaaatatctccacgattcaggaatcgtttattcgatttaccgttactaataaggaaggtatcaaaattagaactaagattccattatctaaggtacatggtctagatgtaaaaaatgtgcagttggtagatgctatagataacatagtttgggaaaagaaatcattagtgacggaaaatcgtcttcacaaagaatgcttgttgagactatcaacagaggaacgtcatatatttttggattacaagaaatatggatcctctatccgactagaattagtcaatcttattcaagcaaaaacaaaaaactttacgatagactttaagctaaaatattttctaggatctggcgctcaatctaaaagttctttattgcacgctattaatcatccaaagtcaaggcctaatacatctctggaaatagaatttacacctagagacaatgaaacagttccatatgatgaactaataaaggaattgacgactctctcgcgtcatatatttatggcttctccagagaatgtaattctttctccacctattaacgcacctataaagacttttatgttgcctaaacaagatatagtaggtctggatctggaaaatctatatgccgtaactaagactgacggcattcctataactatcagagttacatcaaaagggttgtattgttattttacacatcttggttatattattagatatccagttaagagaacaatagattccgaagtagtagtctttggtgaggcagttaaggataagaactggaccgtatatctcattaagctaatagagcccgtaaatgcaatcagtgatagactagaagaaagtaagtatgttgaatctaaactagtggatatttgtgatcggatagtattcaagtcaaagaaatacgaaggtccgtttactacaactagtgaagtcgtcgatatgttatctacatatttaccaaagcaaccagaaggtgttattctgttctattcaaagggacctaaatctaacattgattttaaaatcaaaaaggagaatactatagaccaaactgcaaatgtagtatttaggtacatgtccagtgaaccaattatctttggagagtcgtctatctttatagagtataagaaatttaccaacgataaaggctttcctaaagaatatggttctggtaagattgtgttatataacggcgttaattatctaaataatatctattgtttggaatatattaatacacataatgaagtgggtattaagtccgttgttgtacctattaagtttatagcagaattcttagtcaatggagaaatacttaaacctagaatcgataaaaccatgaaatatattaactcagaagactattatggaaatcaacataatatcatagtcgaacatttaagagatcaaagcatcaaaataggagatgtctttaacgaggataaactatcggatgttggacatcaatacgctgccaacaacgataaatttagattaaatccagaagttagttattttactaataaacgaactagagggccgttgggaattttatcaaactacgtcaagactcttcttatttctatgtattgttccaaaacatttttagacgattccaacaaacgaaaggtattagcgattgattttggaaacggtgctgacctggaaaaatacttttatggagagattgcgttattggtagcgacggatccggatgctgatgctatagctagaggaaatgaaagatacaacaaattaaattctggaattaaaaccaagtactacaaatttgactacattcaggaaactattcgatccgatacatttgtctctagtgtcagagaagtattctattttggaaagtttaatatcattgactggcagttcgctattcattattcttttcatccaagacattatgctacagtcatgaataacttatccgaactaactgcttctggaggcaaggtattaattactaccatggatggagacaaattatcaaaattaaccgataaaaagacttttataattcataagaatctacctagtagcgaaaactatatgtctgtagaaaaaatagctgatgatagaatagtggtatataatccatcaacaatgtctactccaatgactgaatacattatcaaaaagaacgatatagtcagagtgtttaacgaatacggatttgttcttgtagataatgttgatttcgctacaattatagaacgaagtaaaaagtttattaatggcgcatctacaatggaagatagaccgtctacaagaaactttttcgaactaaatagaggagccattaaatgtgaaggtttagatgtcgaagacttacttagttactatgttgtttatgtcttttctaagcggtaaataataatatggtatgggttctgatatccccgttctaaatgcattaaataattccaatagagcgatttttgttcctataggaccttccaactgtggatactctgtattattaatagatatattaatacttttgtagggtaacagaggttctacgtcttctaaaaataaaagttttataacatctggcctgttcataaataaaaacttggcgattctatatatactcttattatcaaatctagccattgtcttatagatgtgagctactgtaggtgtaccatttgattttctttctaatactatatatttctctcgaagaagttcttgcagatcatctgggaataaaatactactgttgagtaaatcagttattttttttatatcgatattgatggacatttttatagttaaggataataagtatcccaaagtagataacgacgataacgaagtatttatacttttaggaaatcacaatgactttatcagatcaaaattaacaaaattaaaggagcatgtatttttttctgaatatattgtgactccagatacatatggatctttatgcgtcgaattaaatgggtctagttttcagcacggtggtagatatatagaggtggaggaatttatagatgctggaagacaagttagatggtgttctacatccaatcatatatctgaagatatacacactgataaatttgtcatttatgatatttatacgtttgattcgttcaagaataaacgattggtatttgtacaggtacctccatcattaggagatgatagctatttaactaatccgttattgtctccgtattatcgtaattcagtagccagacaaatggtcaatgatatgatttttaatcaagattcatttttaaaatatttattagaacatctgattagaagccactatagagtttctaaacatataacaatagttagatacaaggataccgaagaattaaatctaacaagaatatgttataatagagataagtttaaggcgtttgtattcgcttggtttaacggcgtttcggaaaatgaaaaggtactagatacgtataaaaaggtatctgatttgatataatgaattcagtgactatatcacacgcaccatatactattacttatcacgatgattgggaaccagtaatgagtcaattggtagagttttataacgaagtagccagttggttgctacgcgacgagacgtcgcctattcctgataagttctttatacaattgaaacagccgcttagaaataaacgagtatgtgtgtgtggtatagatccgtatccaaaagatggaactggtgtaccgttcgaatcaccaaattttacaaaaaaatcaattaaggagatagcttcatctatatctagattaaccggagtaattgattataaaggttataaccttaatataatagacggggttataccctggaattattacttaagttgtaaattaggagaaacaaaaagtcacgcgatttactgggataagatttccaagttactgctacagcatataactaaacacgttagtgttctttattgtttgggtaaaacagatttctcgaatatacgggcaaagttagaatccccggtaactaccatagtgggatatcatccagcggccagagaccaccaattcgagaaagatcgatcatttgaaattatcaacgttttactggaattagacaacaagacacctataaattgggctcaagggtttatttattaatgctttagtgaaattttaacttgtgttctaaatggatgcggctattagaggtaatgatgttatctttgttcttaagactataggtgtcccgtcagcatgcagacaaaatgaagatccaagattcgtagaagcatttaaatgcgacgagttagaaagatatattgataataatccagaatgtacactattcgaaagtcttagggatgaggaagcatactctatagtcagaattttcatggatgtagatttagacgcgtgtctagacgaaatagattatttaacggctattcaagattttattatcgaggtgtcaaactgtgtagctagattcgcatttacagaatgcggtgccattcatgaaaatgtaataaaatccatgagatctaatttttcattgactaagtctacaaatagagataaaacaagttttcatattatctttttagacacgtataccactatggatacattgatagctatgaaacgaacactattagaattaagtagatcatctgaaaatccactaacaagatcgatagacactgccgtatataggagaaaaacaactcttcgggttgtaggtactaggaaaaatccaaattgcgacactattcatgtaatgcaaccacctcacgataatatagaagattacctattcacttacgtggatatgaacaacaatagttattacttttctctacaacgacgattggaggatttagttcctgataagttatgggaaccagggtttatttcgttcgaagacgctataaaaagagtttcaaaaatattcattaattctataataaactttaatgatctcgatgaaaataattttacaacggtaccactggtcatagattatgtaacaccttgtgcattatgtaaaaaacgatcgcataaacatccgcatcaactatcgttggaaaatggtgctattagaatttacaaaactggtaatccacatagttgtaaagttaaaattgttccgttggatggtaataaactgtttaatattgcacaaagaattttagacactaactctgttttattaaccgaacgaggagaccatatagtttggattaataattcatggaaatttaacagcgaagaacccttgataacaaaactaattctatcaataagacatcaactacctaaggaatattcaagcgaattactctgtccgaggaaacgaaagactgtagaagctaacatacgagacatgttagtagattcagtagagaccgatacctatccggataaacttccgtttaaaaatggtgtattggacctggtagacggaatgttttactctggagatgatgctaaaaaatatacgtgtactgtatcgaccggatttaaatttgacgatacaaaattcgtcgaagacagtccagaaatggaagagttaatgaatatcattaacgatatccaaccattaacggatgaaaataagaaaaatagagagctgtatgaaaaaacattatctagttgtttatgtggtgctaccaaaggatgtttaacattcttttttggagaaaccgcaactgggaagtcgacaaccaaacgtttgttaaagtctgctatcggtgacctgtttgtcgagacgggtcaaacaattttaacagatgtattggataaaggacctaatccatttatcgctaatatgcatttaaaaagatctgtattctgtagcgaactacctgattttgcatgtagtggatcaaagaaaattagatctgataatattaaaaagttgacagaaccttgtgtcattggaagaccgtgtttctccaataaaattaataatagaaaccatgcgacaatcattatcgatactaattacaaacctgtctttgataggatagataacgcattaatgagaagaattgccgtcgtgcgattcagaacacacttttctcaaccttctggtagagaggctgctgaaaataatgacgcgtacgataaagtcaaactattagacgagggattagatggtaaaatacagaataatagatatagattcgcatttctatacttgttggttaaatggtacaaaaaatatcatattcctattatgaaactatatcctacaccggaagagattccggactttgcattctatctcaaaataggtactctgttggtatctagctctgtaaagcatattccattaatgacggacctctccaaaaagggatatatattgtacgataatgtggttactcttccgttgactactttccaacagaaaatatccaagtattttaattctagactatttggacacgatatagagagcttcatcaatagacataagaaatttgccaatgttagtgatgaatatctgcaatatatattcatagaggatatttcatctccgtaaatatatgccatatatttatagaatatatcacatatctaaatgaataccggaatcatagatttatttgataatcatgttgatagtataccaactatattacctcatcagttagctactttagattatctagttagaactatcatagatgagaacagaagcgtgttattgttccatattatgggatcgggtaaaacaataatcgctttgttgttcgccttggtagcttccagatttaaaaaggtttacattttagtaccgaacatcaacatcttaaaaattttcaattataatatgggtgtagctatgaacttgtttaatgacgaattcatagctgagaatatctttattcattccacaacaagtttttattctcttaattataacgataacgtcattaattataacggattaagtcgctacaataactctatttttatcgttgatgaggcacataatatttttgggaataatactggagaacttatgaccgtgataaaaaataaaaacaagattccttttctactattgtctggatctcccattactaacacacctaatacgctgggtcatattatagatttaatgtccgaagagacgatagattttggtgagattattagtcgtggtaagaaagtaattcagacacttcttaacgaacgcggagtgaatgtactcaaggatttgcttaaaggaagaatatcatattacgaaatgccggacaaagatctaccaacaataagatatcacggacgtaaatttctagatactcgagtagtatattgtcacatgtctaaacttcaagagaaagattatatgattactagacggcagctatgttatcatgaaatgtttgataaaaatatgtataacgtgtcaatggcagtattgggacaacttaatctgatgaataatttagatacgttatttcaggaacaggataaggaattgtacccaaatctgaaaataaataatggagtgttatacggtgaagaattggtaacgttaaacattagttccaaatttaagtactttatcaatcggatacagacactcaagggaaaacactttatatacttctctaattctacatatggtggattggtaattaaatatatcatgctcagtaatggatattctgaatataatggttctcagggaactaatccacatatgataaacggcaaaccaaaaacatttgctatcgttactagtaaaatgaaatcgtctttagaggatctattagatgtgtataattctcctgaaaacgatgatggcaatcaattgatgtttttgttttcgtcaaacattatgtctgaatcctatactctgaaagaggtaaggcatatttggtttatgactatcccggatactttttctcaatacaaccaaattcttggacgatctattagaaaattctcttacgtcgatatttctgaacccgttaatgtatatcttttagcagccgtatattcagatttcaatgacgaagtgacgtcattaaacgattatacacaggatgaattgattaatgttttaccctttgacatcaaaaagctgttgtatctaaaatttaagactaaagaaacgaatagaatatactctattcttcaagagatgtctgaaacgtattctcttccaccacatccatcaattgtaaaagttttattgggagaattggtcagacaatttttttataataattctcgtattaagtataacgactccaagttacttaaaatggttacatcagttataaaaaataaagaagacgctaggaattacatagatgatattgtaaacggtcacttctttgtatcgaataaagtatttgataaatctcttttatacaaatacgaaaacgatattattacagtaccgtttagactttcctacgaaccatttgtttggggagttaactttcgtaaagaatataatgtggtatcttctccataaaactgatgagatatataaagaaataaatgtcgagctttgttaccaatggatatcttccagttacattggaaccacatgagttgacgttagacataaaaactaatattaggaatgccgtatataaggcgtatctccatagagaaattagtggtaaaatggccaagaaaatagaaattcgtgaagacgtggaattacctctcggtgaaatagttaataattctgtagttataaacgttccgtgtgtaataacctacgcatattatcacgttggggatatagtcagaggaacattaaacatcgaagatgaatcaaatgtaactattcaatgtggagatttaatctgtaaactaagtagagattcgggtactgtatcatttagcgattcaaagtactgcttttttcgaaatggtaatgcgtatgataacggcatcgaagtctccgccgttctaatggaggctcaacaaggtaccgaatctagttttgtttttctcgcgaatatcgttgactcataagaaagagaatagcggtgagtataaatacgaatactatggcaataattgcgaatgttttattcccttcgatatatttttgataatatgaaaaacatgcctctctcaaatcagacaaccatttcataaaatagttctctcgcactggtgaggtggttgcagctcgtataatctccccagaataatatacttgcgtgtcgtcgttcaatttatacggatttctataattctctgttatataatgaggtttaccctcatgattagacgacgacaatagtgttctgaatttagatagttgatcagaatgaatgtttattggtgttggaaaaattatccatgctgcgtctgcagagtggttgatagttgttcctagatatgtaaaataatccaacgtactaggtagcaaattgtctagataaaatactgaatcaaatggcgcagacatattagcggatctaatggaatccaattgattgactatcttttgaaaatatacatttttatgatctgatacttgtaagaatatagcaataatgataattccatcatcgtgtttttttgcctcttcataagaactatattttttcttattccaatgaaccagattaatctctccagagtatttgtatacatctatcaagtgattggatccataatcgtcttcctttccccaatatatatgtattgttgataacacatattcattggggagaaaccctccacttatatatcctcctttaaaattaatccttactagttttccagtattctggatagtggttggtttcgactcattataatgtatgtctaacgtcttcaatcgcgcgtcagaaattgcttttttagtttctatattaataggagatagttgttgaggcatagtaaaaatgaaatgataactgtctagaaatagctcttagtatgggatttacaatggatgaggaagtgatatttgaaactcctagagaattaatatctattaaacgaataaaagatattccaagatcaaaagacacgcacgtgtttgctgcgtgtataacaagtgacggatatccgttaataggagctagaagaacttcattcgcattccaggcgatattatctcaacaaaattcagattctatctttagagtatccactaaactattacggtttatgtactacaatgaactaagagaaatctttagacggttgagaaaaggttctatcaacaatatcgatcctcacttcgaagagttaatattattgggtggtaaactagataaaaaggaatctattaaagattgtttaagaagagaattaaaagaggaaagtgatgaacatataacagtaaaagaattcggaaatgtaattctaaaacttacaacgagtgataaattatttaataaagtatatataggttattgcatggcatgttttattaatcaatcgttggaggatttatcacatactagtatttacaatgtagaaattagaaagattaaatcgttaaatgattgtattaacgacgataaatacgaatatctgtcttatatttataatatactaattaatagtaaatgagcttttacagatctagtataattagtcagattattaagtataatagacgactagctaagtctattatttgcgaggatgactctcaaattattacactcacggcattcgttaaccaatgcctatggtgtcataaacgagtatccgtgtccgctattttattaactactgataacaaaatattagtatgtaacagacgagatagttttctctattctgaaataattagaactagaaacatgtatagaaagaaacgattatttctgaattattccaattatttgaacaaacaggaaagaagtatactatcgtcatttttttctctagatccagctactgctgataatgatagaataaacgctatttatccgggtggtatacccaaaaggggtgagaacgttccagagtgtttatccagggaaatcaaagaagaagttaatatagacaattcttttgtattcatagacactcgtttttttattcatggtatcatagaagataccattattaacaaattttttgaggtaattttctttgttggacgaatatctctaacgagtgatcaaattattgatacctttaaaagtaatcatgaaataaaggatctaatatttttagatccaaattcaggtaatggactccaatacgaaattgcaaaatatgctctagatactgcaaaacttaaatgttacggtcatagaggatgttattatgaatcattaaaaaaattaactgaggatgattgattagaaaatataaattaatttaccatcgtgtatttttataacgggattgtctggcatatcatgtagatagttaccgtctacatcgtatactctaccatctacgcctttaaatcctctatttattgatattaatctattagaattggaataccaaatattagtaccctcaattagtttattggtaatattttttttagacgatagatcgatggctcttgaaaccaaggttttccaaccggactcattgtctatcggtgagaagtctttttcattagcatgaatccattctaatgatgtatgtttaaacactctaaacaattgtacaaattcttttgatttgttttgaatgatttcaaataggtcttcgtctacagtaggcataccattagataatctagccattataaagtgcacgtttacatatctacgttctggaggagtaagaacgtgactattgagacgaatggctcttcctactatctgacgaagagacgcctcgttccatgtcatatctaaaatgaagatatcattgattgagaagaaactaataccctcgcctccgctagaagagaatacgcatgttttaatgcattctccgttagtgtttgattcttggttaaactcagccaccgccttgattctagtatcttttgttctagatgagaactctatattagagataccaaagactttgaaatatagtaataagatttctattcctgactgattaacaaatggttcaaagactagacatttaccatgggatgctaatattcccaaacatacatctataaatttgacgcttttctcttttaattcagtaaatagagagatatcagccgcaatagcatcccctcccaatagttctccctttttaaaggtgtctaatgcggatttagaaaattctctatctcttaatgaatttttaaaatcattatatagggttgctatctcttgtgcgtattctcccggatcacgattttgtctttcaggaaagctatcgaatgtaaacgtagtagccatacgtctcagaattctaaatgatgatataccagtttttatttctgcgagtttagccttttgataaatctcttcttgcttttttgacatattaacgtatcgcattaatactgttttcttagcgaatgatgcagacccttccacatcatcaaaaatagaaaactcgttattaactatgtacgaacataggcctcctagtttggagactaattctttttcatcgactagacgtttattctcaaatagcgattggtgttgtaaggatcctggtcgcagtaagttaaccaacatggtgaattcttgcacactattaacgataggtgtagccgataaacaaatcatcttatggttttttaacgcaatggtcttagataaaaaattatatactgaccgagtaggacggatcttaccatcttctttgattaatgatttagaaatgaagttatgacattcatcaatgatgacgcatattctactcttggaattaatagttttgatattagtaaaaaatttatttctaaaattttgatcatcgtaattaataaaaatacaatccttcgttatctctggagcgtatctgagtatagtgtttatccaaggatcttctatcaaagccttttttaccaataagataattgcccaattcgtataaatatccttaagatgtttgagaatatatacagtagtcattgttttaccgacacctgtttcatggaacaataaaagagaatgcatactgtctaatcctaagaaaactcttgctacaaaatgttgataatccttgaggcgtactacgtctgaccccatcatttcaacgggcatattagtagttctgcgtaaggcataatcgatataggccgcgtgtgatttactcatttatgagtgataagtaataactatgttttaaaaatcacagcagtagtttaactagccttctctgatgtttgttttcgatactttttgaatcagaagtcatactagaataaagcagcgagtgaacgtaatagagagcttcgtatactctattcgaaaactctaagaacttattaatgaattccgtatccactggatcgtttaaaatactaaattgaacagtgttcacatccttccaagacgaagacttagtgacggacttaacatgagacataaataaatccaaattttttttataaacatcactagccaccataatggcgctatctttcaaccaactatcgcttacgcattttaacagtctaacatttttaaagagactacaatatattctcatagtatcgattacacctctaccgaatagagtgggaagtttaataatacaatatttttcgtttacaaaatcaaataatggtcgaaacacgtcgaaggttaacatcttataatcgctaatgtatagattgttttcagtgagatgattattagatttaatagcatctcgttcacgtttgaacagtttattgcgtgcgctgaggtcggcaactacggcatccgctctagtactcctcccataatactttacgctattaatctttaaaatttcatagactttatctagatcgctttctggtaacatgatatcatgtgtaaaaagttttaacatgtcggtcggcattctatttagatcattaactctagaaatctgaagaaagtaattagctccatattccagactaggtaatgggcttttacctaaagacaagttaagttctggcaatgtttcataaaatggaagaaggacatgtgtcccctcccggatattttttacaatttcatccatttacaactctatagtttgttttcattattattagttattatctcccataatcttggtaatacttacaccttgatcataagataccttatacaggtcattacatacaactaccaattgtttttgtacataatagattggatgattgatatccatggtggaataaactactcgaacagatagtttatctttccccctagatacattggccgtaatagttgtcggcctaaagaatatctttggtgtaaagttaaaagttagggttcttgttccattattgctttttgtcagtagttcgttataaattctcgagatgggcccgttctctgaatatagaacatcatttccaaatctaacttctagtctagaaataatatcggtcttatttttaaaatctattcccttgatgaatggatcgttaataaacaaatccttggcctttgattcggctgatctattatctccgttatagacgttacgttgactagtccaaagacttacaggaatagatgtatcgatgatgttgatagtatgtgatatgtgagcaaagactgttctcttggtggcgtcgctatatgttccagtaatggcggaaaactttttagaaatgttatatataaaagaattttttcgggttccaaacattaacagattagtatgaagataaacactcatattatcaggaacattatcaatttttacataaacatcggcatcttgaatagaaacaacaccatcttctggaacctctacgatctcggcagattccggataaccagtcggtggaccatcactaacaataactagatcatccaacaatctactcacatatgcgtctatataatctttttcatcttgtgagtaccctggatacgaaataaatttgttatcagtatttccataataaggtttagtataaacagagagagatgttgctgcatgaacttcggttactgtcgccgttggttggtttatttgacctattactctcctaggtttctctataaatgatggtttaatttgtacattcttaaccatatatccaataaagctcaattcaggaacataaacaaattctttgttgaacgtttcaaagtcgaacgaagagtcacgaataacgatatcggatactggattgaaggtcaccgttacggtaatttttgaatcggatagtttaagactactgaatgtatcttccacatcaaacggagttttaatataaacgtatactgtagatggttctttaatagtgtcattaggagttaggccaatagaaatatcattaagttcactagaatatccagaatgtttcaaagcaattgtattattgatacaattattatataattcttcgccctcaatttcccaaataacaccgttacacgaagagacagatacatgattaatacatttatatccaacatatggcacgtaaccgaatcttcccatacctttaacttctggaagttccaaactcagaaccaaatgattaagcgcagtaatatactgatccctaatttcgaagctagcgatagcctgattgtctggcccatcgtttgtcataactccggatagagaaatatattgcggcatatataaagttggaatttgactatcaactgcgaagacattagaccgtttaataaagtcatccccaccgatcaaagaattaatgatagtattattcattttctatttaaaatggaaaaagcttacaataaactccgtagagaaatatctataatttgtgagttttccttaaagtaacagcttccgtaaacaccgtctttatctcttagtaagtttattgtatttatgaccttttccttatcttcatagaatactaaaggcaataaagaaatttttggttcttctctaagagctacgtgagacttaaccatagacgccaacgaatccctacatattttagaacagaaatacccaacttcaccacccttgaatgtctcaatactaataggtctaaaaaccaaatcttgattacaaaaccaacacttatcaattacactatttgtcttaatagacatatctgccatagatttataatactttggtagtatacaagcgagtgcttcttctttagcgggcttaaagactgctttaggtgctgaaataaccacatctggaagacttactcgcttagccatttaattacggaactatttttttatacttctaatgaacaagtagaaaacctctcatctacaaaaacatactcgtgtccataatcctctaccatagtaacacgttttttagatctcatatgtgctaaaaagttttcccatactaattggttactattatttttcgtataatttttaacagtttgaggttttagatttttagttacagaagtgatatcgaatattttatccaaaaagaatgagtaattaattgtcttagaaggagtgttttcttggcaaaagaataccaagtgcttaaatatttctactacttcattaatcttttctgtactcagattcagtttctcatcttttacttgattgattatttcaaagactaacttataatcctttttatttattctctcgttagccttaagaaaactagatacaaaatttgcatctacatcatccgtggatatttgatttttttccatgatatccaatagttccgagataatttctccagaacattgatgagacaataatctccgcaatacatttctcaaatgaataagtttattagacacgtggaagtttgactttttttgtacctttgtacatttttgaaatacagactcgcaaaaaatacaatattcatatccttgttcagatactataccgttatgtctacaacagctacataatcgtagattcatgttaacactctacgtatctcgtcgtccaatattttatataaaaacattttatttctagacgttgtcagaaaatcctgtaatatttttagtttttttggttgtgaataaagtatcgccctaataatattggtaccgtcttccgacaatatagtagttaaattatccgagcatgtagaagaacaccgcttaggcggattcagtacaatgttatatttttcgtaccaactcatttaaatatcataatctaaaatagttctgtaatatgtctagcgctaatatattgatcataatcctgtgcataaattaagatacaacaatgtcttgaaatcatcgacatggcttcttccatagttagaagatcatcgtcaaagttagcaacgtgattcatcaacatttgctgttttgaggcagcaaatactgaaccatcaccattcaaccattcataaaaaccatcgtctgaatccattgataatttcttgtactggtttttgagagctcgcatcaatctagcatttctagctcccggattgaaaacagaaagaggatcgtacatccaaggtccattttctgtaaatagaatcgtataatgtcccttcaagaagatatcagacgatccacaatcaaagaattggtctccgagtttgtaacagactgcggactttaacctatacatgataccgtttagcatgatttctggtgatacgtcaatcggagtatcatctattagagatctaaagccggtgtaacattctccgccaaacatattcttattctgacgtcgttctacataaaacatcattgctccattaacgataacaggtgaatgaacagcactacccatcacattagttcccaatggatcaatgtgtgtaactccagaacatcttccatagcctatgttaggaggagcgaacaccactcttccactattgccatcgaatgccatagaataaatatccttggaattgatagaaatcggactgtcggatgttgttatcatcttcataggattaacaacgatgtatggtgcagcctgaagtttcatatcgtaactgatgccgttcataggtctagccacagaaaccaacgtaggtctaaatccaactatagacaaaatagaagctaatatctgttcctcatctgtcataacttgagagcatccagtatgaataatcttcattagatggggatctaccgcatcatcatcgttacaataaaaaattcccattctaatgttcataattgcttttctaatcatggtatgaatgtttgctctctgaatctctgtggaaattagatctgatacacctgtaatcactatcggattatcctccgtaagacgattaaccaacaacatataattataagactttactcttctaaattcataaagttgctggattagactatatgtgtctccatgtacatacgcgttctcgagcgcaggaagtttaataccgaatagtgccatcagaataggatgaatgtagtaattagtttctggttttctataaataaaagacaaatcttgtgaactagacatatcggtaaaatgcatggattggaatcgtgtagtcgacagaagaatatgatgattagatggagagtatattttatctaactctttgagttggtcaccgattctaggactagctcgagaatgaataagtactaagggatgagtacatttcacagaaacactggcgttgttcaacgtactctttacatgggaaaggagttgaaatagctcgtttctatttgtcctgacaatatttagtttattcataatattaagcatatcctgaatagtaaagttagatgtgtcatacttgttagtagttagatatttagcaattgcattcccatcatttctcaatctcgtactccaatcatgtgtggatgctacttcgtcgatggaaaccatacaatcctttttgataggctgttgagattgatcatttcctgtacgtttaggtttggtacgttgatttctagcccctgctgatataaagtcatcgtctacaatttgggataatgaattacatacactacaagacaaagatttatcagaagtgtgaatatgatcttcatctaccaaagaaagagtttgattagtataactagattttagtcccgcgttagatgttaaaaaaacatcgctattgaccacggcttccattatttatattcgtagtttttactcgaaagcgtgattttaatatccaatcttattacttttggaatcgttcaaaacctttgactagttgtagaatttgatctattgccctacgcgtatactcccttgcatcatatacgttcgtcaccagatcgtttgtttcggcctgaagttgacgcatatctttttcaacactcgacatgagatccttaagggtcatatcgtctagattttgttgagatgctgctcctggatttggattttgttgtgctgttgtacatactgtaccaccagtaggtgtaggagtacatacagtggccacaataggaggttgaagaggtgtaaccgttggagtagtacaagaaatacttccatccgattgttgtgtacatgtggttgttggtaacgtctgagaaggttgggtagatggcggtgtcgtcatcttttgatctttattaaatttagagataatatcctgaacagtattgctcggcgtcaacgctggaaggagtgtactcgccggcgcatcagtatctgtagacaaccaatcaaaaagattagacatatcagatgatgtattagtttgttgacgtggttttagtacaggagcagtactactaggtagaagaataggagccggtgtaggtgtcggaaccggctgtggagttatatgaatagttggttgtagcggttgggtaggctgtctgctggcggtcatcatattatctctagctagttgttctcgcaactgtctttgataatacgactcttgagactttagtcctatttcaatcgcttcatcctttttcgtatccggatccttttcttcagaataatagattgacgactttggtgtagaggattctgccagcccctgtgagaacttgttaaagaagtccatttaaggctttaaaattgaattgcgattataagattaaatggcagacacggacgatattatcgactatgaatccgatgatctcaccgaatacgaggatgatgaagaagatggagagtcactagaaactagtgatatagatcccaaatcttcttataagattgtagaatcaacatccactcatatagaagatgcgcattccaatcttaaacatatagggaatcatatatctgctcttaaacgacgctatactagacgtataagtctatttgaaatagcgggtataatagcagaaagctataacttgcttcaacgaggaagattacctctagtttcagaattttctgacgaaacgatgaagcaaaatatgctacatgtaattatacaagagatagaggagggttcttgtcctatagtcatcgaaaagaacggagaattgttgtcggtaaacgattttgataaagatggtctaaaattccatctagactatattatcaaaatttggaaacttcaaaaacgatattagaatttatacgaatatcgttctctaaatgtcacaatcaagtctctcatattcagcagtttattgtcgtactttatatcgtgttcattaacgatattttgcaaaatagtaatgattctatcttccttcgatagatattcttcagagattattgtcttatattctttcttgttatccgatatgaatttgataagactttgaacattattaatacccgtctgtttaattttttctatagatattttagttttggtagattctatggtgtctgttaataggcatccaacatcgacattcgacgtcaattgtctataaatcagagtataaattttagaaataacattagcaaattgttgtgcgttgatgtcgttattctgaaacagtatgattttaggtagcattttcttaacaaagagaacgtatttattgttactcagttgaacagatgatatatccagattactaacgcatctgattccatataccaaactttcagaagaaatggtgtacaattgtttgtattcattcaatgtctccttttcagaaattagtttagagtcgaatactgcaataattttcaagagatagttttcatcagataagattttatttagtgtagatatgataaaactattgttttgttggagaacttgatacgccgcattctctgtagtcgacgctctcaaatgggaaacaatctctattatttttttggaatcggatactatatcttcggtatcttgacgcagtctagtatacatagagttaagagaaattagagtttgtacattaagcaacatgtctctaaatgtggctacaaacttttctttttccacatcatctagtttattatataccgatttcacaacggcaccagatttaaggaaccagaatgaaaaactctgataactacaatatttcatcatagttacgattttatcatcttctatagttggtgtgataacacatacctttttctccaagactggaaccaacgtcataaaaatgtttaaatcaaaatccatatcaacatctgatgcgctaagaccagtctcgcgttcaagattatctttactaatggtgacgaactcatcgtatagaactctaagtttgtccattatttatttacagatttagttgtttaatttatttgtgctcttccagagttgggatagtatttttctaacgtcggtattatattattaggatctacgttcatatgtatcataatattaatcatccacgttttgataaatctatctttagcttctgaaataacgtatttaaacaaaggagaaaaatatttagttacggcatcagacgcgataacattttttgtaaatgtaacgtatttagacgacagatcttcgttaaaaagttttccatctatgtagaatccatcggttgttaacaccattcccgcgtcagagtgaataggagtttgaatagtttgttttggaaatagatccttcaataacttatagttgggtgggaaaaaatcgattttatcactagactctttcttttttactatcattacctcatgaactatttcttgaatgagtatatgtattttctttcctatatcggtcgcgttcattggaaaatatatcatgtcgttaactataagaatatttttatcctcgtttacaaactgaataatatcagatatagttcgtaaacgaactatatcatcaccagcacaacatctaactatatgatatccactagtttcctttagccgtttattatcttgttccatattagcagtcattccatcatttaagaaggcgtcaaagataatagggagaaatgacattttggattctgttacgactttaccaaaattaaggatatacggacttactatctttttctcaacgtcgatttgatgaacacacgatgaaaatgtacttcgatgagattgatcatgtagaaaacaacaagggatacaatatttccgcatatcatgaaatatattaagaaatcccactttattatatttccccaaaggatcaatgcatgtaaacattataccgttatcattaataaagacttctttctcatcggatctgtaaaagttgttactgatttttttcattccaggatctagataattaataataatgggttttctattcttattctttgtattttgacatatcctagaccagtaaacagtttccactttggtaaaatcagaagacttttgaacgctattaaacatggcattaatggcaataactaaaaatgtaaaatatttttctatgttaggaatatggtttttcactttaatagatatatggttttttgccaaaatgatagatatttttttatccgatgatagtaaaatattattagtcgccgtctctataaaaatgaagctagtctcgatatccaattttattctagaattgataggagtcgccaaatgtaccttatacgttatatctcccttgatgcgttccatttgtgtatctatatcggacacaagatctgtaaatagttttacgttattaatcatcacggtatcgccatcgctagataatgctaatgtactatccaagtcccaaatggagagatttaactgttcatcgtttagaataaaatgattacctgtcatattaataaagtgttcatcgtatctagataacaacgacttataattaatgtccaagtcttgaactcgctgaatgatcttttttaacccagttagttttagattggtacgaaatatattgttaaactttgattctacagtaatgtccaaatctagttgtggaaatacttccatcaacattgtttcaaacttgataatattattatctacatcttcgtacgatccaaattccggaatagatgtatcgcacgctctggccacccagataaccaaaaagtcacacgctccagaatatacattgtataaaaagctatcgttttttagtagtgtttttttctgagtatatacgaaaggattaaaaatagtattatcaacgtaactatattccaaattattcttatgagaatagataataatatcgtccttaatatctaacaaatttcctaaatatccctttaattgagtcattcgaagcgttaataaaatatgtctcttaactatttccggccgttgtatatttaaatgacttcgtaagaaataatatataggcgacttctcatctatgtaatcatatggagtgagatatagggctcgttctacctcctgccccttacccacctgtaataccaattgcggactcactatatatcgcatatttatatcgtggggtaaagtgaaaatctactaccgatgatgtaagtcttacaatgttcgaaccagtaccagatcttaatttggaggcctccgtagaactaggggaggtaaatatagatcaaacaacacctatgataaaggagaatagcggttttatatcccgtagtagacgtctattcgcccatagatctaaggatgatgagagaaaactagcactacgattctttttacaaagactttattttttagatcatagagagattcattatttgttcagatgcgtcgacgctgtaaaagacgtcactattaccaaaaaaaataacattatcgtggcgccttatatagcacttttaactatcgcatcaaaaggatgcaaacttacagaaacaatgattgaagcattctttccagaactatataatgaacatagtaagaaattcaaattcaactctcaagtatccatcatccaagaaaaactcggataccagtctggaaactatcacgtttatgattttgaaccgtattactctacagtagctctggctattcgagatgaacattcatctggcatttttaatatccgtcaagagagttatcttgtaagttcattatctgaaataacatatagattttatctaattaatctaaaatctgatcttgttcaatggagtgctagtacgggcgctgtaattaatcaaatggtaaatactgtattgattacagtgtatgaaaaattacaactggccatagaaaatgattcacaatttacatgttcattggctgtggaatcagaacttccaataaaattacttaaagatagaaatgaattatttacaaaattcattaacgagttaaaaaagaccagttcattcaagataagcaaacgtgataaggatacgctattaaaacattttacttatgactggagttagaatttatagacgacacatttcgtttatcattgttactattactatcattattagtattcttcttgtcatcttgttcagaaatatacagcaatgctatacctaatactaaatacattatcatgcttgcaatggctctaacaacaacgaaccaaaatgaatttggtcgtagcttttgttcacaaaaatacataaagaaatgtctacataaatctatggcgccattggctacttgaaatagcgccagtcctcctacagattttaatatagctgtataacatgacatttattcatcatcaaaagagacagagtcaccatctgtcatatttagattttttttcatgtgttcaaagtatcctctactcatttcattataatagtttatcatgcttagaattttaggacggatcaatgagtaagacttgactagatcgtcagtagtaatttgtgcatcatctattctgcatccgcttcgtcgaataatgtatagcatcgctttgagattctccatagctatcaagtctttatataatgacatggaaatatctgtgaatgctttatacttctccaacatcgatgccttaacatcatcacatactttagcattgaaaatacgttctattgtgtagatggatgtagcaagatttttaaacaacaatgccatcttacatgatgattgtctcaagtctccaatcgtttgtttagaacgattagctacagagtccaatgcttggctaactagcatattattatctttagaaattgtattcttcaatgaggcgtttatcatatctgtgatttcgttagtcatattacagtctgactgggttgtaatgttatccaacatatcacctatggatacggtacacgtaccagcatttgtaataatcctatctaagatgttgtatggcattgcgcagaaaatatcttctcctgtaatatctccactctcgataaatctactcagattattcttaaatgccttattctctggagaaaagatatcagtgtccatcatttcattaatagtatacgcagaaaagataccacgagtatcaattctatccaagatacttatcggttccgagtcacagataattgtttcctctccttcgggagatcctgcatagaaatatctaggacaatagtttctatactgtctgtaactctgataatctctaaagtcactaactgataccatgaaattgagaagatcaaacgctgaagtaatcaatttttctgcctcgtttttactacaactagttttcatcaatgtagtgacgatgtattgtttagttactcttggtctaatactgatgatagagatattattgcttcccataatggatcttctagtagtcaccttaaagcccattgatgcgaatagcagatagataaagtcttggtatgactcctttctaatatagtacggactacctttgtcacccaactttatacccacataagccataacaacctctttaatagccgtttcatgaggtttatcagccatgagcctgagtagttgaaagaatcgcatgaatcccgtctcagaaagtcctatatgcatgatagatttatctttcctgggaaactctcgtatagttatagatgaaatactcttcaaagtttctgaaataagattagtaacagtcttacctccgactactctgggtaacaaacatactctaataggtgttttctctgcggagataatatcagaaaggatagagcaataagtagtattattgtgattataaagaccgaatacataacaggtagaatttataaacatcatgtcctgaagggttttagacttgtattcctcgtaatctataccgtcccaaaacatggatttggtaactttgatagccgtagatctttgttccttcgctaacaggttaaagaaattaataaagaatttgttgtttctatttatgtccacaaattgcacgtttggaagcgccacggttacattcactgcagcattttgaggatcgcgagtatgaagtacgatgttattgtttactggtatatctggaaagaaatctaccagtctaggaataagagattgatatcgcatagaaatagtaaagtttataatctcatcattgaagattactctgttaccattgtaataaattggtactctatcataatcatcgacaaagtactgttcatacatgatgagatgtttatatgttggcatagtagtgagatcgacgtttggtaatggcaatgtattaagattaactccataatgtctagcagcatctgcgatgttataagtgatgtcaaagcggggttgatcttgtgctgttatatattgtctaacacctataagattatcaaaatcttgtctgcttaatacaccgttaacaatttttgccttgaattcttttattggtgcattaataacatccttatagaggatgttaaacaaataagtattatcaaagttaagatctgggtatttcttttctgctagaacatccattgagtcggagccatctggtttaatataaccaccgataaatctagctctgtattctgtatccgtcaatctaatattaagaaggtgttgagtgaaaggtggaagatcgtaaaagctgtgagtattaataatagggttagtttccgaactaatgttaattggatgattaataatatttatatttccagcgttaagtgtaacattaaacagttttaattcacgtgacgtggtatcaattaaataattaatgcccaatttggatatagtagcctgaagctcatcttgtttagttacggatcctaatgagttattaagaaatacatcgaacggatgaacgaaggttgttttaagttggtcacatactttgtaatctagacatagatgtggaagaacggtagaaactatacgaaatagatattcagagtcctctaattgatcaagagtaactattgacttaataggcatcatttatttagtattaaatgacgaccgtaccagtgacagatatacaaaacgacttaattacagagttttcagaagataattatccatctaacaaaaattatgaaataactcttcgccaaatgtctattctaactcacgttaacaacgtggtagatagagaacataatgccgccgtagtgtcatctccagaggaaatatcatcacaacttaatgaagatctatttccagatgatgattcaccggccactattatcgaacgagtacaacctcatactactattattgacgatacgccacctcctacttttcgtagagagttattgatatcggaacaacgtcaacaacgagaaaaaagatttaatattacagtatcaaaaaattctgaagcaataatggaatctagatctatgataacttctatgccaacacaaacaccatccttgggagtagtttatgataaagataaaagaattcagatgctagaggatgaagtggttaatcttagaaatcaacgatctaatacaaaatcatctgataatttagataattttaccagaatactatttggtaagactccgtataaatcaaccgaagttaataagcgtatagccatcgttaattatgcaaatttgaacgggtcccccttatcagtcgaggacttggatgtctgttcggaggatgaaatagatagaatctataaaacgattaaacaatatcacgaaagtagaaaacgaaaaattatcgtcactaacgtgattattattgtcataaacattattgagcaggcattgctaaaactcggatttgaagaaatcaaaggactgagtaccgatatcacttcagaaattatcgatgtggagatcggagatgactgcgatgctgtagcatcaaaactaggaatcggtaacagtccggttcttaatattgtattgtttatactcaagatattcgttaaacgaattaaaattatttaatttaatacattcccatatccagacaacaatcgtctggattaatctgttcctgtcgtctcataccggacgacatattaatctttttattagtgggcatctttttagatggtttctttttcccagcattaactgattcgatacctagaagatcgtgattgatttctccgaccattccacgaacttctaattggccgtctctaacggtaccataaactattttaccagcattagtaacagcttggacaatctgaccatccattgcgttgaatgatgtagttgctgttgttctacgtctaggagcaccagaggtatttttagagctcttggatgttgatgtagaagacgaggattttgattttggtttacatgtaatacattttgaactctttgattttgtatcacatgcaccggcagtcacatctgtttgagaattaagattattgttgcctcctttgacggctgcatctccaccgatctgcgctagtagatttttaagctgtggtgtaatcttattaactgtttcaatataatcatcgtaactacttctaacggctaaattttttttatccgccatttagaagctaaaaatatttttatttatgcagaagatttaactagattatacaatgaactaatatgatccttttctagattatttacgaacttggtatttcttgtttctggaggaggagaatttaaattcggacttggattcggattttgtgggttcttgatcttattatacagcgtgtataggatggtgacggtaactgctacacaaataccgatcaacagaagaataccaatcatttattgacaataacttcactatgatcaagtatgtaataatcatcttttcactaagtaagtagtaataatgattcaacaatgacacgatatatggacgataataatttagttcatggaaatatcgctatgattggtgtgaatgactccgctaactctgtggggtgcacagtgctttccccacatagaataaattagcattccgactgtgataataataccaagtataaacgccataatactcaatactttccatgtacgagtgggactggtagacttactaaagtcaataaaggcgaagatacacgaaagaatcaaaagaatgattccagcgattagcacgccagaaaaataatttccaatcataagcatcatgtccatttaactaataaaaattttaaatcgccgaataaacaaagtggaatataaaccatataaaaacaatagtttgtactgcaaaaataatatctatttttgttttcgaagatatggtaaaattaaatagtagtacacagcatgttataactaacagcagcaacggctcgtaattacttatcatttactagacgaaaaggtggtgggatattttcttgctcaaataatacgaatatatcacccatccattttatacgatgtttatatactctaatctttaatagatctatagatgacgggtttaccaataatatagattttatcgattcatctaatttaaacccttccttaaacgtgaatgatctattatctggcataatgatgaccctacctgatgaatctgacaatgtactgggccatgtagaataaattatcaacgaattatcgtctacgaacatttatatcatttgttttaattttaggacgtgaataaatagatataaaatagaaaataacagatattacaaccagtgttatggacgcacccaaccatgtaggcagttttattttatcgtttactacaggttctcctggatgtacgtcaccaactgcagacgtagttctagtacaattagacgtaagttccgcttgggaattttttaacgctaaagagttaacgttgatcgtacacccaacgtatttacatctagttctttgaacatcttgattataatataaccattttctatctctagattcgtcagtgcactcatgtaaccaacataccctaggtcctaaatatttatctccggaattagattttggataattcgcgcaccaacaatttctatttcctttatggtcgttacaaaagacgtataatgccgtatccccaaaagtaaaataatcaggacgaataattctaataaactcagaacaatatctcgcatccatatgtttggagcaaatatcggaataagtagacatagccggtttccgttttacacgtaaccattctaaacaattggggtttccaggatcgtttctacaaaaaccagtcatgaaatcgtcacaatgttctgtcttgtaattattattaaatatttttggacagtgtttggtatttgtcttagaacaacattttgccacgctatcactatcacccaggagataatccttttttataaaatgacatcgttgcccggatgctatataatcagtagcatattttaaatccttaatatattcaggagttacctcgttctgataatagattaatgatccaggacgaaatttgaaagaactacatggttctccatgaattaatacatattgtttagcaaattcaggaactataaaactactacaatgatctatcgacataccatctatcaaacaaaatttgggtttaatttctcctggagacgtttcataataatacatataactttcttcggcaaacctaacagctctattatattcaggataattaaaatctaataccatatatttgtctcgtatatctgctattcctgtctctattttgattctattaagagtaacagctgcccccattcttaataatcatcagtatttaaactgttaaatgttggtatatcaacatctatcttatttcccgcagtataaggtttgttgcaggtatactgttcaggaatgggtacatttatacttcttttatagtcctgtctttcgatgttcatcacaaatgcaaagaacagaataaacaaaataatgtaagaaataatattaaatatctgtgaattcgtaaatacattgattgccataataattacagcagctacaatacacacaatagacattcccacagtgttgccattacctccacgatacatttgagttactaagcaataggtaataactaagctagtaagaggcaatagaaaagatgagataaatatcatcaatatagagattagaggagggctatatagagccaagacgaacaaaatcaaaccgagtaacgttctaacatcattatttttgaagattcccaaataatcattcattattcctccataatcgttttgcatcatacccccatctttaggcataaacgattgctgctgttcctctgtaaataaatctttatcaagcactccagcacccgcagagaagtcatcaagcatattgtaatatcttaaataactcatttatatattaaaaaatgtcactattaaagatggagtataatctttatgccgaactaaaaaaaatgacttgtggtcagaccataagtctttttaatgaagacggcgatttcgtagaagttgaaccaggatcatcctttaagtttctaatacctaagggattttactcctctccttgtgtaaagacgagtctagtattcaagacattaacaacgaccgataataaaattactagtatcaatccaacaaatgcgccaaagttatatcctcttcaacgcaaagtcgtatctgaagtagtttctaatatgaggaaaatgatcgaattaaaacgtcctctatacatcactcttcacttggcatgtggatttggtaagactattaccacgtgttatcttatgaccacacacggcagaaaaaccatcatttgcgtacccaataaaatgttaatacatcaatggaagacacaggtagaggcagtcggattggaacataagatatctatagatggagttagtagtctattaaaggaactaaagactcaaagtccggatgtattaatcgtagtcagtagacatctgacaaacgatgcattttgtaaatatatcaataagcattatgatttgtttatcttggatgaatcacatacgtataatctgatgaacaatacagcagttacaagatttttagcgtattatcctccgatgatgtgttattttttaactgctacacctagaccagctaaccaaatttattgtaatagtattattaatattgccaagttatccgatctaaaaaaaactatctatatagtagatagtttttttgagccatattccacagacaatattagaaatatggtaaaacgactagatggaccatctaataaatatcatatatataccgagaagttattatctgtagacgagcctagaaaccaacttattcttgataccctggtagaagaattcaagtcaggaactattaatagaattttagttattactaaactacgtgaacatatggtattcttctacaaacgattattagatcttttcggagcagaggttgtatttataggagacgcccaaaatagacgtactccagatatggtcaaatcgattaaggaactaaatagatttatattcgtatccaccttattttattccggcactggtttagatattccgagtttggattctttgttcatttgctcggcagtaatcaacaatatgcaaatagagcaattactagggagggtatgtcgagaaacagaactattagataggacggtatatgtatttcctaacacatccatcaaaaaaataaagtacatgataggaaatttcgtgcaacgaattattagtctgtctgtagataaactcggatttaaacaagaaagttatcagaaacatcaggaatctgaacccgcttccgtaccaacatcctccagagaagaacgtgtattaaatagaatatttaactcgcaaaatcgttaagaagtttaagagacgatccacatgctgagcaggccagtgtattacccctcatagtattaatataatccaatgatacttttgtgatgtcggaaatcttaaccaatttagactgacaggcagaacacgtcatacaatcatcatcgtcatcgataactgtagtcttgggcttctttttgcgactcttcattccggaacgcatattggtgctatccatttaggtagtaaaaaataagtcagaatatgccctataacacgatcgtgcaaaacctggtatatcgtctctatctttatcacaatatagtgtatcaacatctttattattgacctcgtttatcttggaacatggaatgggaacatttttgttaacggccacctttgccttaattccagatgttgtaaaattataactaaacagtctatcatcgacacaaatgaaattcttgtttagacgtttgtagtttacgtatgcggctcgttctcgtctcattttttcagatattgcaggtactataatattaaaaataagaatgaaataacataggattaaaaataaagttatcatgacttctagtgctgatttaactaacttaaaagaattacttagtctgtacaaaagtttgagattttcagattctgtggctatagagaagtataattctttggtagaatggggaacatctacttactggaaaataggcgtacaaaaggtaactaatgtcgagacgtccatatctgattattatgatgaggtaaaaaataaaccgtttaatattgatccggggtattatattttcttaccagtatattttggaagcgtctttatttattcaaagggtaaaaatatggtagaacttggatctggaaactcttttcaaataccggatgagattcgaagtgcgtgtaacaaagtattagatagtgataacggaatagactttctgagatttgttttgttaaacaatagatggataatggaagacgctatatcaaaataccagtctccagttaatatatttaaactagctagtgagtacggattaaacatacccaactatttagaaattgaaatagaggaagacacattatttgacgatgagttatactctattatggaacgctctttcgatgatacatttccaaaaatatctatatcgtatattaagttgggagaacttaagcggcaagttgtagactttttcaaattctcattcatgtatattgagtcaatcaaggtagatcgtataggagataatatttttattcctagcgttataacaaaatcaggaaaaaagatattagtaaaagatgtagaccatttaatacgatccaaggttagagaacatacatttgtaaaagtaaaaaagaaaaacacattttccattttatacgactatgatgggaacggaacagaaactagaggagaagtaataaaacgaattatagacactataggacgagactattatgttaatggaaagtatttctctaaggttggtattgcaggcttaaagcaattgactaataaattagatattaatgagtgtgcaactgtcgatgagttagttgatgagattaataaatccggaactgtaaaacgaaaaataaaaaaccaatcagtatttgatttaagcagagaatgtttgggatatccagaagcggattttataacgttagttaataacatgcggttcaaaatagaaaattgtaaggttgtaaatttcaatattgaaaatactaattgtttaaataacccgagtattgaaactatatatggaaacttcaaccagttcgtctcaatctttaataccgttaccgatgtcaaaaaaagattattcgagtgaaataatatgcgcctttgatataggtgcaaaaaatcctgccagaactgttttagaagtcaaggataactccgttagggtattggatatatcaaaattagactggagttctgattgggaaaggcgcatagctcaagatttgtcacaatatgaatacactacagttcttctagaacgtcagcctagaaggtcaccgtacgtcaaatttatctattttattaaaggctttttatatcatacatctgctgccaaagttatttgcgtctcacctgtcatgtctggtaattcatatagagatcgaaaaaagagatctgttgaagcatttcttgattggatggacacattcggattgcgagactccgttccggatagacgcaaattagacgatgtagcggatagtttcaatttggctatgagatacgtattagataaatggaatactaattatacaccttataataggtgtaaatatagaaattacataaaaaaaatgtaataacgttagtaacgccattatggataatctatttacctttctacatgaaatagaagatagatatgccagaactatttttaactttcatctaataagttgtgatgaaataggagatatatatggtcttatgaaagaacgcatttcctcagaggatatgtttgacaatatagtatataataaagatatacatcctgccattaagaaactagtttattgcgacatccaacttactaaacatattattaatcagaatacgtatccggtatttaacgattcttcacaagtgaaatgttgtcattatttcgatataaactcaaataatagcaatattagctctcgtacagtagagatatttgagagtgaaaagtcatctcttgtatcatatattaaaactaccaataagaagagaaaggtcaattacggcgaaataaagaaaactgtacatggaggcactaatgcaaattacttttccggtaaaaagtctgatgagtatctgagcactacagtcaggtccaacattaatcaaccttggatcaaaaccatttctaagagaatgagagtagatatcattaatcactctatagtaacgcgtggaaaaagctctatattacaaactatagaaattatttttactaatagaacatgtgtgaaaatattcaaggattctactatgcacattattctatccaaggacaaggatgaaaagggatgtataaacatgattgataaattattctatgtatattataatttatttctgttgttcgaggatatcatccaaaacgattactttaaagaagtagctaatgttgtaaaccatgtactcatggctacggcattagatgagaaattattcctaattaagaaaatggctgaacacgatgtttatggagttagcaatttcaaaatagggatgtttaacctgacatttattaagttgttggatcataccgttttcccctctctgttagatgaggatagcaaaataaagttttttaaggggaaaaagctcaatattgtagcattacgatctctggaggattgtacaaattacgtgactaaatccgagaatatgatagaaatgatgaaggaaagatcgactattttaaatagcatagatatagaaacggaatcggtagatcgtctaaaagaattgcttctaaaatgaaaaaaaacactgattcagaaatggatcaacgactcgggtataagtttttggtgcctgatcctaaagccggagttttttatagaccgttacatttccaatatgtatcgtattctaattttatattgcatcgattgcatgaaatcttgaccgtcaagcggccactcttatcgtttaagaataatacagaacgaattatgatagaaattagcaatgttaaagtgactcctccagattactcacctataattgcgagtattaaaggtaagagttatgacgcattagccacgttcactgtaaatatctttaaagaggtaatgaccaaagagggtatatccatcactaaaataagtagttatgagggaaaagattctcatttgataaaaattccgctactaataggatatgggaataaaaatccacttgatacagccaagtatcttgttcctaatgtcataggtggagtctttatcaataaacaatctgtcgaaaaagtaggaattaatctagtagaaaagattacaacatggccaaaatttagggttgttaagccaaactcattcactttctcgttttcctccgtatcccctcctaatgtattaccgacaagatatcgccattacaagatatctctggatatatcacaattggaagcgtcgaatatatcatcgacaaagacatttataacggtcaatattgttttgctgtctcaatatttatctagagtgagtctagaattcattagacgtagtttatcatacgatatgcctccagaagttgtctatctagtaaacgcgataatagatagtgctaaacgacttaccgaatctattactgactttaatattgatacatacattaatgacctggtggaagctgaacacattaaacaaaaatctcagttaacgattaacgagtttaaatatgaaatgctgcataactttttacctcatatgaactatacacccgatcaactaaagggattttatatgatatctttactaagaaagtttctctactgtatctaccacacttctagatatccagatagagattcgatggtttgtcatcgcatcctaacgtacggcaaatattttgagacgttagcacatgatgaattagagaattacataggtaacatccgaaacgatatcatgaacaatcacaagaacagaggcacttacgcagtaaacattcatgtactaacaactcctggacttaatcatgcattttctagtctattgagtggaaagttcaaaaagtcagacggtagttatcgaacacatcctcactattcatggatgcagaatatttctattcctagaagtgttggattttatccggatcaagtaaagatttcaaagatgttttctgtcagaaaataccatccaagccaatatctttacttttgttcatcagacgttccggaaagaggtcctcaggtaggtttagtatctcaattgtctgtcttgagttccattacaaatatactaacgtctgagtatttggatttggaaaagaaaatttgtgagtatatcagatcatattataaagatgatataagttactttgaaacaggatttccaatcactatagaaaatgctctagtcgcatctcttaatccaaatatgatatgtgattttgtaactgactttagacgtagaaaacggatgggattcttcggtaacttggaggtaggtattactttagttagggatcacatgaatgaaattcgcattaatattggagcaggaagattagtcagaccattcttggttgtggataacggagagctcatgatggatgtgtgtccggagttagaaagcagattagacgacatgacattctctgacattcagaaagagtttccacatgtcatcgaaatggtagatatagaacaatttacttttagtaacgtatgtgaatcggttcaaaaatttagaatgatgtcaaaggatgaaagaaagcaatacgatttatgtgactttcctgccgaatttagagatggatatgtagcatcttcactagtgggaatcaatcacaattctggacccagagctattcttggatgtgctcaagctaaacaagctatctcttgtctgagttcggatatacgaaataaaatagacaatggaattcatttgatgtatccagagaggccaattgtgattagtaaggctttagaaacttcaaagattgcggctaattgcttcggacaacatgttactatagcattaatgtcgtacaaaggtatcaatcaagaggatggaattatcatcaaaaaacaatttattcagagaggcggtctcgatattgttacagccaagaaacatcaagtagaaattccattggaaaactttaataacaaagaaagagataggtctaacgcctattcgaaattagaaagtaatggattagttagactgaatgctttcttggaatccggagacgctatggcaagaaatatctcatcaagaactcttgaagatgattttgctagagataatcagattagctttgatgtttccgagaaatatacagatatgtacaaatctcgcgttgaacgagtacaagtagaacttactgacaaagttaaggtgcgagtattaaccatgaaagaaagaagacccattctaggagacaaatttactactagaacgagtcaaaagggaacagtcgcgtatatcgcagatgaaacggaacttccgtacgacgaaaatggtatcacaccagatgtcattattaattctacatccatcttctctagaaaaactatatctatgttgatagaagttattttaacagccgcatattctactaagccgtacaacaataagggagaaaaccgacctgtctgttttcctagtagtaacgaaacatctatcgatgcatatatgcaattcgctaaacaatgttatgagtattcaaatccgaaattgtccgaggaagaattatcggataaaatcttttgtgaaaagattctctatgatcctgaaacggataagccttatgaatccaaagtattttttggaccaatttattacttgcgtctgagacatttaactcaggacaaggcaaccgttagatgtagaggtaaaaagacgaagctcattagacaagcgaatgagggacgaaaacgtggaggaggtatcaagtttggagaaatggagagagactgtttaatagcacatggtgcagccaatactattacagaagttttaaaagactcagaagaggattatcaagatgtgtatatttgtgaaaattgtggagacatagcagcacaaatcaaaagtattaatacatgtcttagatgttcaaaacttaatctctctcctctcttaacaaaaattgataccacgcacgtatctaaagtatttcttactcaaatgaacgccagaggcgtaaaagttaaattagatttcgaacgaaggcctccttcgttttataaaccattagataaagttgatcttaaaccgtcttttctggtataatattgtttagtagatactcatcaagataagctaattcactaaacatattatcggattcggtattgttactcgagaatagagttcgttatgctcctgatattcggaaatctgtggagtttcaggttttggtggaagtgtaactgctacttggtgggatactgaaggatatttcagagagttgtggatgttcgggttcgacatccaccgatggtgtcacgccactaatcggttcggtaacgtctgtggatggaggtgctacttctacagaacctgtagcctcagttgtcaacggagatacatattcaatgcgcggaaatgtataatttggtaatggtttctcatgtggatcttaagaagaagaggtaagatatctacgaaagataccgatcacgtttctagttctcttttgtagaactttaactttttctttctcagcatctagttgatattccgacctcttcacgtttcgcatgggttacctccgcagtttttacaagcgatttcacgttccagatcacgttcagccttcatacgtctctccctctctctatcgagtttatcagagcagtctttctgaaggcgatcgaactccataaatttctccaacgctttgattgtttccatagatttccgaagtttagcttctaggacggcgattctttttttttttttttttttttttttcgaattcacggggtacaaccgtttccattaccaccatctctatgtttcttttctagatcggcaatctttctcaatctttctcaacatttcatccccataccttttcattcctcgagtctattgtcgtcgaaatatcgttccagctccttttcgacctcaataactttagcacgttgtttcatcaagctctctcttgtagtactatcatttttatctgattccctgacacgtttaagatcttcatgtaattgagtcagctcttgacgcaatctcttaactaacttcctctcttgcttcttcgtcatagtacttacaatcactatgggatccattgttaccacgtctgtactcgacgagctcacgtttaagagattcaatttccagtttgtatcggtccatgtctccattgctacaccaccattagatttacaggctgctagttgtcgttcgagatcagaaatacgtgttttcttggaatggatttcgtcgatgtacttgtcatgattggcatcgaaacacttattaagttctttttttcaattctacgattttatttctttcgcgagtcaattccctcctgtagtaactatcagttttgtcagattcacgctctctacgtagactttcttgtaagttactaatttgttccctggcattaccgagttcagttttatatgccgaatagagttctgattcatcctttgagaagatctctagcgatcgttcaagatccctgattctagtctttagcctatttacctcctcagaagatgctccgttaccgtttttacaatcgttaagatgtctatcaagatccatgattctatctcttttccatatcagcattgatttcattattacgttcgcagtcgttcaactgtatttcaagatctgagattctagattgtaatctctgtagcatttccacggcattcactcagttgtctttcaagatctgagattctagattggagtctgctaatctctgtaagatttcctcctccgctctcgatgcagtcggtcaacttattctctagttctctaatacgcgaacgcagtgcatcaacttcttgtgtgtcttcttgattgcgtgtgcattcatcgagtctagattcgagatctctaacgtgacgtcgttcttcctcaagttctctgtgtactacagaaagcgtgtccctatcttgttgatatttagcaatttctgattctagagtactgattctactcacgtatgtactaatagttgtcttagccttatcaagatcctccttgtatttgtcacattccttgatatccatacgaagtctggacagttcccattcgacattacgacgtttatcgatttcagctcggagatcgtcgtcgcgttgttttagccacatacgactaagttcaagttctcgttgacaagatccatctacttttccatccctaatagtatccagttccttttctagttctgaccgcatttctcgttccatatcaagagattctctcaattctcgtatagtcttcttatcaatttctgatgaatctgaaccatcatctgtcccattttgttgcatatccctgagttctttgatctctgttgtaagtctgtcgattctttcggttttataaacagaatccctttccaaagtcctaatcttactgagtttatcattaagttcttcattcaattcagtgagttttctcttggcttcttccaagtctgttttaaactctccatcatttccgcattcttcctcgcatttatctaaccattcaattagtttattaataactagttggtaatcagcgattcctatagccgttcttgtatttgtgggaacataattaggatcttctaatggattgtatggcttgatagcatcatctttatcattattaggtgggggatggacaaccttaattggttggtcctccttatctcctccagtagcatgtggttcttcaataccagtattagtaataggcttagacaaatgcttgtcgtacgcgggcacttcctcatccatcaagtatttataatcgggttctgtttcagaatattcttttctaagagacgcgacttcaggagttagtagaagaactctgtttctgtatctatcaacgctggaatcgatactcaagttaaggatagcgaatacctcatcgtcatcatccgtatcttctgaaacgccatcatatgacatttcatgaagtctaacgtattgataaacagaatcagatttagtattaaacagatccttgacctttttagtaaatgcatatgtatattttagatctccagatttcataatatgatcgcatgccttaaatgtcaatgcttccatgatatagtctggaacactaatgggtgacgaaaaagatacagcaccatatgctacgttgataaatagatctgaaccactaagtagataatgattaatgttaaggaagaggaaatattcagtatatagatatgccttagcatcatatcttgtactaaacacgctaaacagtttattgatgtgatcaatttccaacagaacaattagagcggcaggaataccaacaaacatattaccacatccgtattttctatgaatatcacatatcatattaaaaaatcttgatagaagagcgaatatctcgtctgacttaatgagatgtagttcagcagcataagtcataactgtaaatagaacatactttcctgtagtgttgattctagactccacatcaacaccattattaaaaatagttttatatacatctttaatctgctctccgttaatcgtcgaacgttctagtatacggaaacactttgatttcttatctgtagttaatgacttagtgatatcacgaagaatattacgaattacatttcttgtttttcttgagagacctgattcagaactcaactcatcgttccatagtttttctacctcagtggcgaaatctttggagtgtttggtacattttttaataaggttcgtgacctccatttattataaaaaatttttattcaaaacttaactacaatcgggtaattataagatcgtagatctcccatgtggtggaatactaccatctatcgcatgttgatggacagtaggtaatggccatgggaacagtaatgtttgcatatttatctttcttgctagtattactgtatattgtcccaatgtttcaatgtgatgttctaacctatcaactgccactgtatcacaacaataatgtccgatggaattaagattatgatccaatgtgtttaatatatgattatcaagtcttatacgatccgcgtcttttttgacaggatcaggctcttctacaggaagaagtttcggcctcttatgatagtcatgtctgggaaatggtggtctaggatgaggatcaggtatcggagtaggttttggattataatcatcatcatcatcatcatcatcatcatcatcatcatcatctatgatatcatcatcttcgatatttattttgctatcttgataatgtcctatatcagttgcattttcagcactcgactgaatattagtacattcattgtctattattaacgtatttctaaacccaaaatgtatatgttgaacatcactactatagttgatgagtcttatagcatgaattcgcttatcgttatcgggtttatcttctgtcaccttaacaattccttttttattaaactctgcataatcataaccatttctattgtttgttctaatataaacgagtatagcatcattgctaaatttttcaatagtatcaaaaacagaatatcctaaaccatataatatatattcaggaacactcaaactaaatgtccaggattctcctaaatacgtaaactttaatagtgctaaatcattcaaaaatctaccgcttatagatagatagtacatgaatgcgtatagtagtctacctatctctttattatgaaaaccgacattacgatcatatatttcgtgatatacatgtgacccgtttacgttaaaccataaatacatgggtgatcctataaacatgaatttatttctaattctcagagccatagttaattgaccgtgtaatatttgtttacatgcatacttgatacgatcattaataagatttttatcattgctcgttatttcagaatcgtatatataaggagtaccatcatgattcttaccagatattatacaaaatactatatataaaatatattgacccacgttagtaatcatgtaaatgtttaatgttttaaattttgtatttaatgatccatcatcatatgctagcatggtcttgtgatattcattctttaaaatataatattgtgttagccattgcattggagctcctaatggagattttctattctcgtccattttaggatatgctttcataaagtccctaataacttcgtgaataatgtttctatgttttctactgatgcatgtatttgcttcgatttttttatcccatgtttcatctatcatagatttaaacgcagtaatgctcgcaacattaacatcttgaaccattggtacaattccgttccataaatttataatgttcgccatttatataactcattttttgaatatacttttaattgaacaaaagagttaagttactcatatggatgccgtccagtctgtacatcaatctttttagccagagatatcatagccgctcttagagtttcagcgtgattttccaacctaaatagaacttcatcgttgcgtttacaacacttttctatttgttcaaactttgttgttatattagtaatctttttttccaaattagttagccgttgtttgagagtttcctcattatcgtctccataggctttaacaattgcttcgcgtttagtctctggatttttagcagcctttgtagagaaaaattcagttgctggaattgcaagatcgtcatctccggggaaaagagttccgtccatttaaagtacagattttagaaactgacactctgtgttatttatatttggcgcaatacatggattataaatatcgatgttaataacatcagaaaatgtaaagtctatacattgtcgcatcgtgttaaattttctaatggatctagtattattgggtccaacttctgcctgaaatccaaatatggaagcggatacaaaaccgtttcctggataaaccacacatctccacttttgctttacatcagaaattgtgtcattgacatcttgaactctcctatctaatgccggtgttccacctatagattttgaatactcgaatgctgcatgagtagcattgaattccttaatattgccataattttcatatattgagtaactctggataaaaagtaaacacaccgcagccgtcgctactacaataaaaaaaattgatagagagttcatttataatctattagaagctgataaaatttttttacacgcgtcagacaatgctttaataaatagttcaacatctacttttgtcatatcgaaccgatggtatgattctaacctagaattacatccgaaaaagttgactatgttcatagtcattaagtcattaacgaacaacattccagactctggattataagacgatactgtttcgtcacaatcacccaccttaatcatgtgattatgaatattggctattagagtaccttctaagaaatctataatatctttgaaacacgatttaaaatcaaaccacgaatatacttctacgaagaaagttagtttacccataggagagataactataaatggagatctagatacaaaatccggatctatgatagttttaacattattatattctctattaaatacctccacatctaaaaatgttaattttgaaactatgtcttcgtttattaccgtacctgaactaaacgctataagctctattgtttgagaactctttaaacgatattcttgaaatacatgtaacaaagtttcctttaactcggtcggtttatctaccatagttacagaatttgtatccttatctataatataataatcaaaatcgtataaagttatataattatcgtgttcagattgtgatcttttcaaatagactaaaaaccccatttctctagtaagtatcttatgtatatgtttgtaaaatatcttcatggtgggaatatgctctacagcagttagccattcctcattgacagctgtagatgtattatacaaaactactccaatgtttaacaagggccattttacgagattattaaatccttgtttgataaatgtagccaatgcgggttcgagttcaacgacgattgaattctcttcccgtggatgctgcatgatgaacgacgggatgttgttgttctattgatttggaattctttttcgactttttgtttatattaaatattttaaaatttatggctgatagtaattcatgtactacggataatgtagacgtgtattgcatatcgatatctttattattagataaatttatcaataaatgtgagaagtttgcctcgttaaggtcttccatttaaatattatataaatatttgtgtttgtattttattcgtcttttatgggatagtttttaactagtaaagctgtaattacatactttgtccgtaaaacataaatataaatacccgcttttatcaaacgttccaaaaagtcggcagctgacatttttaacatgacatctattttaaatacacttaggtttttagaaaaaacatcattttataattgtaacgattcaataactaaagaaaagattaagattaaacataagggaatgttatttgtattttataagccaaagcattctaccgttgttaaatacttgtctggaggaggtatatatcatgatgatttggttgtattggggaaggtaacaattaatgatctaaagatgatgctattttacatggatttatcatatcatggagtgacaagtagtggagcaatttacaaattgggatcgtctatcgatagactttctctaaataggactattgttacaaaagttaataacaattataacaattataacaattataacaattataattgttataataattataattgttataattatgatgatacattttttgacgatgatgattgatcactattacacaattttgtttttgtactttctaatatagtgtttaggttctttttcatatgagaatattgacttactaaaatatctatgtttaacttttgttctataacgtccttatcggcggtatcggtacatatacgtaattcaccttcacaaaatacggagtcttcgataataatagccaatcgattattggatctagctgtctgtatcatattcaacatgtttaatatatcctttcgtttcccctttacaggcatcgatcgtagcatattttccgcgtctgagatggaaatgttaaaactgcaaaaatgcgtaatgttagcccgtcctaatattggtacgtgtctataagtttggcatagtagaataatagacgtgtttaaatgccttccaaagtttaagaattctattagagtattacattttgatagtttatcacctacatcatcaaaaataagtaaaaagtgtgctgattttttatgattttgtgcgacagcaatacatttttctatgttacttttagttcgtatcagattatattctagagcttcctgactactaacgaaattaatatgatttggccaaatgtatccatcataatctgggttataaacgggtgtaaacaagaatatatgtttatattttttaactagtgtagaaaacagagatagtaaatagatagtttttccagatccagatcctcctgttaaaaccattctaaacggcatttttaataaattttctcttgaaaattgtttttcttgaaaacaattcataattatatttacagttactaaattaatttgataataaatcaaaatatggaaaactaaggtcgttagtagggaggagaacaacgaaggcatatcgtgatataaataacatttattatcatgatgacaccagaaaacgacgaagagcagacatctgtgttctccgctactgtttacggagacaaaattcagggaaagaataaacgcaaacgcgtgattggtctatgtattagaatatctatggttatttcactactatctatgattaccatgtccgcgtttctcatagtgcgcctaaatcaatgcatgtctgctaacaaggctgctattactgactccgctgttgccgttgctgcggcatcatctactcatagaaaggttgtgtctagcactacacaatatgatcacaaagaaagctgtaatggtttatattaccagggttcttgttatatattacattcagactataagtcattcgaggatgctaaagcaaactgcgctgcggaatcatcaacactacccaataaatccgatgtcttgactacctggctcattgattatgttgaggatacatggggatctgatggtaatccaattacaaaaactacatccgattatcaagattctgatgtatcacaagaagttagaaagtatttttgtacataaataaatgaaatcgcttaatagacaaactgtaagtaggtttaggaagttgtcggtgccggccgctataatgatgttactctcaaccattattagcggcataggaacatttctgcattacagagaagaactgatgcctagtgcttgcgccaatggatggatacaatacgataaacattgttatctggataccaacattaaaatgtctacggataatgcagtttatcagtgtcgcaaattacgagctagattgcctagacctgatactagacatctgagagtattgtttagtattttttataaagattattgggtaagtttaaaaaagaccaatgataaatggttagatattaataatgataaagatatagatattagtaaattaacaaattttaagcaactaaacagcacgacggattctgaggcgtgttatatatacaagtctggaaaactggttaaaacagtatgtaaaagtactcaatctgtactatgcgttaaaagattctacaagtgacaacaaaaaatgaattaatagtaagtcgttaacgtacgccgccatggacgccgcgtttgttattactccaatgggtgtgttgactataacagatacattgtatgatgatctcgatatctcaatcatggactttataggaccatacattataggtaacataaaaattgtccaaatagatgtacgggatataaaatattccgacatgcaaaaatgctactttagctataagggtaaaatagttcctcaggattctaatgatttggctagattcaacatttatagtatttgtacagcatacagatcaaaaaataccatcatcatagcatgcgactatgatatcatgttagatatagaaggtaaacatcaaccattttatctattcccatctattgatgtttttaacgctacaatcatagaagcgtataatctgtatacagctggagattatcatctgatcatcaatccttcagataatctgaaaatgaaattgtcgtttaattcttcattttgtatatcagacggcaatggatggattataattgatgggaaatgtaatagtaattttttatcataaaagttgtaaagtaaataataaaacaataaatattgaactagtagtatgttgtatattgagcaatcagagatgatgctggtacctcttatcacggtgaccgtagttgcgggaacaatattagtatgttatatattatatatttgtaggaaaaagatacgtactgtctataatgacaataaaattatcatgacaaaattaaaaaagataaagagtcctaattccagcaaatctagtaaatcaactgatagcgaatcagactgggaggatcactgtagtgctatggaacaaaacaatgacgtagataatatttctagaaatgagatattgaacgatgatagcttcgctggtagtttaatatgggataacgaatccaatatcatggcgcctagcacagaacacatttacgatagtgttgctggaagcacgctgctaataaataatgatcgtaatgaacagactatttatcagaatactacagtagtaattaatgatacagagactgttgaaatacttaatgaagataccaaacagattcctagctattcttccaatcctttcgtaaattataataaaaccagtatttgtagcaagtcaaatccgttcattgcagaactcaacaataaatttagtgataataatccgtttaggagagcacatagtgacgattatcttaataagcaacaagatcatgaatacgatgatatagaatcatcggttgtatcattggtctgattagtttcctttttataaaattgaagtaatatttagtattaattaccgccgatgcattatacaaatatggagatattccctgtattcggcatttctaaaattagcaattttattgctaataatgactgtagatattatatagatgtagagcatcaaaaaattatatctgatgagatcaatagacagatggatgaaacggtacttcttaccaacatcttaagcgtagaagttgtaaatgacaatgagatgtaccatcttattccccatagactatcgactattatactctgtattagttctgttggaggatgtgttatctctatagataatgacgtcaatgacaaaaatattctaacatttcccattgatcatgctgtaatcatatccccactgagtaaatgtgtcgtagttagcaagggccctacaaccatactggttgttaaagcggatatacccagcaaacgattggtaacatcgtttacaaacgacatactgtatgtaaacaatctatcactgattaattatttaccgtcgtctgtattcattattagacgagtcaccgactatttggatagacacatatgtgatcagatatttgctaataataagtggtattccattataactatcgacgataagcaatatcctattccatcaaattgtataggtatgtcttctgccaagtacataaattcgagcatcgagcaagatattttgatccatgtttgtaacctcgagcatccattcgactcagtctacaaaaaaatgcagtcgtacaattctctacctatcaaggaacaaatattgtatggtagaattgataatataaatatgagcattagtatttcggtggattaatagatttctctagtatgggatcattaatcatctctaaatacatcataaaaaagctattatcaaatactgtactgaatggattcattcttttctctttttatgaaactctgttgtatatctacggataaaactagaagcaaaaaatctgataggaagaataatgattatatggaggaacacgattattataaaataacaatagttcctggttcctcttccacgtctactagctcgtggtattatacacatgcctagtaatagtctctttgcgttgacggaaagcagactagaaataacaggccaaaatgttcagacaccataatagttcccaacccagataataacagagttccatcaacacattcctttaaactcaatcccaaacccaaaaccgttaaaatgtatccagccaattgatagtagataatgaggtgtacagcacatgataatttacacagtaaccaaaatgaaaacactttagtaattataagaaatatagacggtaatgtcatcatcaacaatccaataatatgcctgagagtaaacattgacggataaaacaaaaatgccccgcataactctatcatggcaataacgcaaccaaacacttgtaaaattcctaaattagtagaaaatacaactgatatcgatgtataagcgatttcgaggaataataagaacaaagtaattcccgtaaagataaacatcaacattgtttggtaatcattaaaccaattagtatgacgttgaattaatttcacagtatattttattccagtattatccccgcatgtatacgtacctggtaagatatctttatattccataatcaatgagacatcactatccgataacgaatgaagtctagcactagtatgccatttacttaatatggtcgtcttggaagttttattataagttaaaatatcatgattgtccaatttccatctaatatactttgtcggattatctataatacacggaataatgatggtatcattacatgctgtatattctatagtctttgtagatgttataaccacaaaagtacagaggtatatcaacaatattctaactcttaacatttttatttatttaaaatgatacctttgttatttattttattcttattttgctaacggtatcgaatggcataagtttgaaacgagtgaagaaataatttctacttacttaatagattatgtggtaacgggtgttattaatggggatgtatatacattttcaaataatgaactaaacaaaactgggttaactaataacaataattatatcacaacatctataaaagtagaggataaggatacattagtagtatgcggaaccaataacggaaatcccaaatgttggaaaatagacggttcatactacccaaaacatataggtagaggatacgatcatcaaaatagcaaagtaacgataatcagtcacaatgaatgtgtactatccgacataaacatataaaaagaaggaattaaacgatggagaagatttgacggaccatgtggttatgattaaacgagttaagttttttaagaagccttagaagagaggctattgggtatgagaatccgaaatattaaaccagacaaccccatataattttatagctaagaatgccgcgaagaatggaactaataaaaacggaaatatttgtagcacaacgaataactcccaaactgcattcatgttacactatataacactacttcggttagatgttttagaaaaaataaatatcaccgtaccgttttgttgtataaaaataacaattaacaattatcaatttttttctttaatattttacgtggttgaccattcttggtggtaaaataatctcttagtgttggaatggaatgctgtttaatgtttccacactcatcgtatattttgacgtatgcagtcacatcgtttacgcaatagtcagactgtagttctatcatgcttcctacgttagaaggaggaacagttttaaagtctcttggttttaatctattgtcattagttttcatgaaatcctttgttttatccacttcacattttaaataaatgtccactatacattcttctgttaattttactagatcatcatgagtcatagaattcataggttccgtagtccatggatccaaactagcaaacttcgcgtatacggtatcgcgattagtgtatacaccaactgtatgaaaattaagaaaacagtttaataaatctacagaaatatttaatcctccgtttgatacagatgcgccatatttatggatttcggattcacacgttgtttgtctaaggggttcgtctagtgttgcttctacatagacttcgattcccatatattctttattgccagaatcacataccgatttatcatacgctggttcacttgtttgaaaactaaatggtagtagatacatcaaaataataaataataagtacattctgcaatattgttatcgtaattggaaaattggtattcaagtgagctggattatgtgagtattggattgtatattttattttatattttatattttatattttattttatattttatattttattttatattttgtagtaagaatagaatgctaatgtcaagtttattcgaatagatgtcttattaaaaaacatatataataaataacaatggctgaatggcataaaattatcgaggatatctcaaaaaataataagttcgaggatgccgccatcgttgattacaagactacaaagaatgttctagcggctattcctaacagaacatttgcaaagattaatccgggtgaagttattcccctcatcactaatcataatattctaaaacctcttattggtcagaaattttgtattgtatatactaactctctaatggatgagaacacgtatgctatggagttgcttactgggtacgcccctgtatctccgatcgttatagcgagaactcataccgcacttatatttttgatgggtaagccaacaacatccagacgtgatgtgtatagaacatgtagagatcacgctacccgtgtacgtgcaactggtaattaaaataaaaagtaatattcatatgtagtgtcaattttaaatgatgatgaaatggataatatccatattgacgatgtcaataatgccggtattgacatacagctcatcgatttttagatttcattcagaggatattgaattatgttatgggaatttgtattttgataggatctataataatgtagtaaatataaaatatattcctgagcatattccatatagatataattttattaatcgtacgttctccgtagatgaactagatgataatgtcttttttacacatggttattttttaaaacacaaatatggttgttcacttaatcctagtttgattgtctcattatcaggaaacttaaaatataatgatatacaatgctcagtaaatgtatcgtgtctcattaaaaatttggcaacgagtacatctactatattaacatctaaacataagacttattctctatatcggtccatgtgtattgctataataggatacgattctattatatggtataaatatataaatgacaggtataatgacatctatgattttactgcaatatgtatgctaatagcgtctacattgatagtgatcatatacgtgtttaaaaaaataaaaatgaactcttaattatgttatactattagaaatggataaaatcaaaattacgattgattcaaaaattggtaatgttgttaccatatcgtataacttggaaaagataactattgatgtcacgccaaaaaagaaaaaagaaaaggatgtattattagcgcaatcagttgctgtcgaagaggcaaaagatgtcaaggtggaagaaaaaaatattatcgatattgaagatgacgatgatatggatatagaaaacacgtaatacgatctataaaaataagtattaaatactttttatttacggtactcttgtagtggtgataccactaatcgattattttttttaaaaaaatacttattctgattcttctagccatttccgtgttcgttcgaatgccacatcgacgtcaaaaataggggagtagttgaaatctagttctgcattgttggtacgcacctcaaatgtagtgttggatatcttcaacgtatagttgttgagtattgatggttttctaaatagaattctcttcatatcattcttgcacgcgtacatttttagcatccatcttggaatcctagatccttgttctattcccaatggtttcatcaatagaagattaaacatatcgtaagaacacgatggagagtaatcgtagcaaaagtaagcatttcctttaatcgcagatcccggatactggatatattttgcagccaacacgtgcatccatgcaacatttcctacatatacccggctatgcacagcgtcatcatcgactgtacgatacataatgttaccgtgttgcttacattgctcgtaaaagactttcgtcaatttgtctccttctccgtaaattccagtgggtcttaggcaacaagtatacaattttgcgccattcatgattacggaattattggctttcataaccagttgctcggccatacgtttactttttgcgtatacatgtcctggtgatatatcataaagggtatgctcatgaccgatgaatggattaccgtgtttatttggtcctattgcttccatgctactagtatagatcaaatacttgattcctaggtccacacaagctgccaatatagtctgtgttccataatagtttactttcatgatttcattatcagtgtattttccaaatacatccactagagcagccgtatgaataatcagatttaccccatctagcgcttctctcaccttatcaaagtcgtttatatcacattgtatatagtttataaccttaactttcgaggttattggttgtggatcttctacaatatctatgactcttatttcttgaacatcatctgcgctaattaaaagttttactatatacctgcctagaaatccggcaccgccagtaaccgcgtacacggccattgctgccactcataatatcagactacttattctattttactaaataatggctgtttgtataatagaccacgataatatcagaggagttatttacgttgaacaagtccatggaaaagataaagttttaggatcagttattggattaaaatccggaacgtatagtttgataattcatcgttacggagatattagtcgaggatgtgattccataggcagtccagaaatatttatcggtaacatctttgtaaacagatatggtgtagcatatgtttatttagatacagatgtaaatatatctacaattattggaaaggcgttatctatttcaaaaaatgatcagagattagcgtgtggagttattggtatttcgtacataaatgaaaagataatacattttcttacaattaacgagaatggcgtttgatatatcagttaatgcgtctaaaacaataaatgcattagtttacttttctactcagcaagataaattagtcatacgtaatgaagttaatgatatacactacactgtcgaatttgatagggacaaagtagttgatacgtttatttcatataatagacataatgactccatagagataagaggggtgcttccagaggaaactaatattggtcgcgtggttaatacgccggttagtatgacttacttgtataataagtatagttttaaaccgattttagcagaatatataagacacagaaatactatatccggcaacatttattcggcattgatgacgctagatgatttggttattaaacagtatggagacattgatctattatttaatgagaaacttaaagtagactccgattcgggactatttgactttgtcaactttgtaaaggatatgatatgttgtgattctagaatagtagtagctctatctagtctagtatctaaacattgggaattgacaaataaaaagtataggtgtatggcattagccgaacatatagctgatagtattccaatatctgagctatctagactacgatacaatctatgtaagtatctacgcggacacactgatagcatagaggatgaatttgattattttgaagacgatgatttgtctacatgttctgccgtaaccgatagggaaacggatgtataattttttttatagtatgaaggatatgatggatatgatgatatgatggatatgatgatatgatggatatgatggatatgatggatatgatggatatgataaaaaaatataattgttgtatccattcccattcaaatcaccttatatgattctgtaacacaatgaaggagtctcatagatatatagaggtcagatactggtttgataaactttttattccacatgagcatgtttgacttatggttagacacacatactttaacaaatcactgaaaattggagttaggtattcctctcagaatcagttgccgttctggaacattaaatgtattttttatgatatactccaacgcatttatgtgggtatacaacaagtcattaataatgagtatttccaagagttttagttgtctagtatttaacaagagaagagatttcaacagactgtttatgaactcgaataccgcctcattgtcgcttatattgatgacatgacatcgaattcccaatatcaatctcatcagtgatgagtagctcaatcttgttatcgggatccaatttctaaagatgtcattaaaccctcgatcgtgaatggatttatcatcatcgtttttatgttggacatgagcttagtccgtttgtccacatctatatacgatgatttctgaattatttcatatatctctcgttaactccaggaacttgtcagggatctaactttaatatgttctcgtctaagagatgaaaatctttggatggttgcatgtgacttttctctaaaggatgatgttacccgatcctctcttaaatgactccatcttatccttggacaagatggacagtctattttccttagatggtttaatattttttacccatgatctataaaggtagacagacctaatcgtctcggatgaccatatattattttccgttttattatacgcataaattgtaaaaaatatgttaggtttacgaaaatgtctcgtggggcattaatcgtttttgaaggattggacaaatctggaaaaacaacacaatgtatgaacatcatggaatctataccggcaaacacgataaaatatcttaactttcctcagcgatccacagtcactggaaagatgatagatgactatctaactcgtaaaaaaacctataatgatcatatagttaatctattattttgtgcaaatagatgggagtttgcatcttttatacaagaacaactagaacagggaattactttaatagttgacagatacgcgttctctggagtagcgtatgccaccgctaaaggcgcgtcaatgactctcagtaagagttatgaatctggattgcctaaacccgacttagttatattcttggaatctggtagcaaagaaattaatagaaacatcggcgaggaaatttatgaagatgttgaattccaacaaaaggtattacaagaatataaaaaaatgattgaagaaggagatattcattggcaaattatttcttctgaattcgaggaagatgtaaagaaggagttgattaagaatatagttatagaggctatacacacggttactggaccagtggggcaactgtggatgtaataaaatgaaattacatttttataaatagatgttagtacagtgttataaatggatgaagcatattactctggcaacttggaatcagtactcggggatacgtgtccgatatgcataccgaactcgcatcaatatctcaattagttattgccaagatagaaactatagataatgattattaaacaaggacattgtaaattttatcatgtgtagatcaaacttggataatccatttatctctttcctagatactgcatatactatcatagatcaagagatctatcagaacgagttgattaattcattagacgataatgaaattatcgattgtatagttaacaagtttatgagcttttataaggataacctagaaaatatggtagatgctatcattactctaaaatattataattaataatccagattttaaaactacgtatgtggaagtactcggttccagaatagctgatatagatattaaacaagtgatacgtaagaatataatacaattgtctaatgatccgcgaacgatatttgtgaaaatattaaaaaaaaatactttttttattaaatgacgtctcttcgcgaatttagaaaattatgctgtgatatatatcacgcatcaggatataaagaaaaatctaaattaattagagactttataacagatagagatgataccgatacatatttgatcattaagctattgcttcccggattagacgatagaatgtataacatgaacgataaacaaattataaaattatatagtataatatttaaacaatctcaggaagatatgctacaagatttaggatacggatatataggagacactattaggactttcttcaaagagaacacggaaatccgtccacgagataaaagcattttaactttagaagaagtggatagttttttaactacgttatcatcagtaactaaagaatcacatcaaataaaattattgactgatatagcatctgtttgtacatgtaatgatttaaaatgtgtagtcatgcttattgataaagatctaaaaattaaagcgggtcctcggtacgtgcttaacgctattagtcctcatgcctatgatgtttttagaaaatctaataacttgaaagagataatagaaaatgcagctaaacaaaatctagactctatatctatttctgttatgactccaattaatcccatgttagcggaatcatgtgattctgtcaataaggcgtttaaaaaatttccatcaggaatgtttgcggaagtcaaatacgatggtgaaagagtacaagttcataaaaaaaataacgagtttgcattctttagtagaaacatgaaaccagtactctctcataaagtggattatctcaaagaatacataccgaaagcatttaaaaaagctacgtctatcgtattggattctgaaattgttcttgtagacgaacataatgtaccgctaccgtttggaagtttaggtatacacaaaaagaaagaatataaaaactctaacatgtgtttgttcgtatttgactgtttatactttgatggattcgatatgacagacattccattgtatgaacgaagatcttttctcaaagatgttatggtcgaaatacccaatagaatagtattctcagagttgacgaatattagtaacgagtctcagttaactgatgtattagatgatgcactaacgagaaaattagaaggattggtcttaaaagatattaatggcgtatacgaaccgggaaagagaagatggttaaaaataaagcgagactatttgaacgagggttccatggcagattctgccgatttagtagtactaggtgcctactatggtaaaggaggaaagggtggtatcatggcagtctttctaatgggttgttacgacgatgaatccggtaaatggaagacggtaactaaatgttccggtcacgatgataatacgttaagggttttgcaagaccaattaacgatggttaaaattaacaaggatcccaaaaaaattccagagtggttggtagttaataaaatctatattcccgattttgtagtagatgatccgaaacaatctcagatatgggaaatttcaggagcagagtttacatcttccaagtcacatacagcgaatggaatatcgattagatttcctagatttactaggattagagaagataaaacgtggaaagaatctactcatctaaacgatttagtaaacttgactaaatctcttaatagttacatataaactgaaaaataaaataacactattttagttggtagtcgccatggatggtgttatcgtatactgtctaaatgcgttagtaaaacatggcgaggaaataaatcatataaaaaatgatttcatgattaaaccatgttgtgaaagagtttgtgaaaaagtcaagaacgttcacatcggcggacaatctaaaaacaatacagtgattgcagatttgccatatctggataatgctgtatcagatgtatgcaaatcaatatataaaaagaatgtatcaagaatatccagatttgctaatttgataaaaatagatgacgatgacaagactcctaccggcgtatataattattttaaacctaaagatgctattcctgttattatatccataggaaaggataaagatgtctgtgaactattaatctcatctgataaagcgtgtgcgtgtataaagttaaatttatataaagtagccattcttcccatggatgtttccttttttaccaaaggaaatgcatcattgattattctcctgtttgatttctctatcgatgcggcacctctcttaagaagtgtaaccgataataatgttattatatctagacaccagcgcctacatgacgagcttccgagttccaattggttcaagttttacataagtataaagtccgactattgttctatattatatatggttgttgatggatctatgatgtatgcgatagctgataatagaactcacgcaattattagcaaaaatatattagacaatactacgattaacgatgagtgtagatgctgttattctgaaccacagattaggattcttgatagagatgagatgctcaatggatcatcgtgttatatgaacagacattgtattatgatgaatttacctgatgtaggcgaatttggatctagtatgttggggaaatatgaacctgacatgattaagattgctctttcggtggctggtaatttaataagaaatcgagactacattcccgggagacgaggctatagctactacgtttacggtatagcctctagataattttttttaagcacgaaataaaaacataattttaaacaatctatttcatactattttgtgtgctcaccatgaacataaagatagatatattagtatttctggtgataaatttacggcgactgctaggagggaaaatgaagaaagaaaaaatatctacctctccaaaaagaaaaactactgatgttatcaaacctgattatcttgagtacaatgacttgttagatagagatgagatgtctactattctagaggaatattaggccttagaataaaatatggacgactcttaacgaaattagaaaattcgataatgatgttgaagaacaattcggtactatagaagaactcaagcagaagcttagattaaattctgaagagagagcagataattttatagattatataaaggtacaaaaacaggatatcatcaaacttactgtatacgattgcatatatctatgataggattgtgtgcgtgcgtggtagatgtttggagaaatgagaaactgttttctagatggaaatattggttacaagcgattaaactgtttattgatgatcacatgcttgataagataaaatctattgtagaatagactagtgtatgtggaaatgtcatagaaagttaaaagttaatgagagcaaaaatatataaggttgtattccatatttgttatttttttctgtaatagttagaaaatacattcgatggtctatctaccagattattatgtgttataaggtacttttctcataataaactagagtatgagtaagatagtgtttttcaaaaacatataaatctaaaattgatggatgagatatacagctattaatttcgaaaatatattttaatctgataactttaaacatggatttttgatggtggtttaagtttaaaaaagattttgttattgtagtatgataatatcaaaaagatggatataaagaatttactgactacatgtactattttacattactacattggctacggcatatatacctatttcgtcacttccacacgctccggtaaacgggtgtcatgtgacgagggagaatcttgataagaggcataatcaatgttgtaatccgatgtccacctggagaatttgccaaggtcagatgtagagttggtagtgataacacaaaatgtgaacactgcccacctcatacatataccgcaatccccaattattctaatagatgtcatcaatgtagaaaatgcccaacaggatcatttgataaggtaaagtgtaccggaacacagaacaaatgttcgtgtcatcctggttggtatacgctactgattcttcacagactgaagattgtcgagatttgtgtaccaaaaaaggagatgtccatgcggatactttggtggaatagatgaaggaaatcctatttgtaaatcgtgttgtgttggtgaatattgcgactacctacgtaattatagacttgatccatttcctccatgcaaactatctatctaaatgtaattaattatgattttgatgataatgttaccatacattatatcactacttggttagtgtgtattatttagtatggaagacctattaataattacttatcttttgacgatcttgttataattataatataaaaatacttatgacatagtaactcataattgctgacgcgataaattcgtaataatctgttttgttcaaatttttataaggaatctacaggcataaaaataaaaatataatctataatatactcttacaacgccatcatgaatagcagtgaattaattgctgttattatggatttagaaatagtggacgattttgtgatattaatatagttattaatgatgaaaggataaacgcgcatagactcatcctatctggagcctccgaatattttttccattctgttttccaataattttatcgattctaatgaatacgaagttaatctaagtcatttagattatcaaagtgttaactatttgatcgattacatttatgggatacctttgagcctaactaacaataacgtgaaatatattctttcaaccgctgatttttttacaaattggatctgtcattactgagtgcgaaaaatacatacttaaaaatctttgttttagaaactgtatcgatttctacatatacgctgataaatataataacaagaaaatagaattagcatcgtttaacacaatattacgaaatattttgagactcatcaacaatgaaaactttaaatacttaacagaggaatcaatgataaaaattttaagcgatgatatgttatatataaaaaatgaggatttcaccccactgattctcattaaatggttagagagtacaccaaccatgtaccgtcgagttacttagatgcctcagaatatcatttctttccccacaagttataaaatcactttatagtcatcgactggttagttcaatctacgaatgtataacattcttaaacaatatagcattcttggataaatcatttcctagataccatatcatcgagttgatatctatcggtataagtaattcacatgataagatttccataaactgctacaatcataaaaaaattcatgggaaatgatatcttcacgtagatataggtgtagtttcgcagtgaccgtcctggataatattatctatatgatgggtggatatgatcagtccctgtatagaagttcaaaggttatagcgtacaatacatgtactaattcttggatatatgatataccagagctaaaaatatcatcgttctaattgcggaggagttgccaatgacgaatacatttattgtataggcggtatacgcgatcaggagtcatcgttgatatctagtatcgatagatggaagccatcaaaaccatattggcagaagtatgctaaaatgtgcgaaccaaaatgtgatatggggttgcgattttaaacggattaatatatgtcataggtggagtcgttaaaggtgacacacatataccaacgcactagagagtttatcagaagatggatggatgaatcatcaacgtcttccaataaaaatgtccaatatgtcgacgattgttcatgctggaaagatttatatatctagaggttacaacaatagtagtgtagttaatgtaatatcgaatctagtccttagctataatccgatatatgatgaatggaccaaattatcatcattaaatattcctagaattaatcctgctctatggtcagtgtataataaattatatgtaggaggagtaatatctgatgatgttcaaactaatacatctgaaacatacgataaagaaaaagattgttggacattggataatggtcacttgttaccacataattatataatgtataaatgcgaaccgtttaaacatagatatccattggaaaaaacacagtacacgaatgattttctaaagtatttggaaagttttataggtagttgatagaacaaaatacataattttgtaaaaataaatcactttttatactaatatgacacaattaccaatacttttgttactaatatcattagtatacgctacaccttctcctcagacatctaaaaaaataggtgatgatgcaactatatcatgtagtcgaaataatacaaattactacgttgttatgagtgcttggtataaggagcccaattccattattctcttagctgccaaaagcgacgtcttgtattttgataattataccaaggataaaatatcttacgactctccatacgatgatctagttacaactatcacaattaaatcattgactgctggagatgccggtacttatatatgtgcattctttatgacatcgactacaaatgatactgataaagtagattatgaagaatactccatagagttgattgtaaatacagatagtgaatcgactatagacataatactatctggatctacaccagaaactatttctgagaaaccagaggatatagataattctaattgctcgtctgtattcgaaatcacgactccggaaccaattactgataatgtagacgaccatacagacaccgtcacatacactagtgatagcattaatacagtaaatgcatcatctggagaatccacaacagacgagattccggaaccaattactgataaagaagaagatcatacagtaacagacactgtctcatacactacagtaagtacatcatctggaattgtcactactaaatcaaccaccgatgatgcggatctttatgatacatacaatgataatgatacagtaccgccaactactgtaggtggtagtacaacctctattagcaattataaaaccaaggacttcgtagaaatatttggtattaccacattaattatattgtcagcagtggcgattttctgtattacgtattatatatgtaataaacacccacgtaaatacaaaacagagaacaaagtctagatttttgacttacataaatatctgggataataaaatctatcatattgagaggaccatctggttcaggaaagacagccataaccaaaagactgttaaaagactatgggaatatatttggatttgtggtgtcccataccactagatttcctcgtcctatggaacgagaaggtgttgattaccttacgttaacagagaggccatctggaagggaatagccgccggaaactttctagaacatactgagtttttaggaaatatttacggaacttctaaaacagctgtaaatacagcggttattaataatcgtatttgcgcgatggatttaaacatcaacggtgttagaagtcttaaaaatacttacctaatgcattacttgggtatataagacctacctctcttaaaatggttgagaccaatcttcgtcgtagaaacactgaagcggacgacgaatctcatcgtcgcgtgatgttggcaaaaaacggatatggatgaggtcaacgaagcaggtctattcgacactattattattgaagatgatgtgaatttagcatatagtaagtgttaattcagatactacaggaccgtattagaatgtattttaacactaattagagacttaagatttgacttaaaacttgataattaataatataactcgtttttatatgtggctatttcaacgtctaatgtattagttaaatattaaaacttaccacgtaaaacttaaaatttaaaatggtatttcattgacagatcatacattatgaagtttcaaggacttgtgttaattgacaattgcaaaaatcaatgggtcgttggaccattaataggaaaaggtggattcggtagtatttatactactaatgacaataattatgtagtaaaaatagagcccaaagctaacggatcattatttaccgaacaggcattttatactagagtacttaaaccatccgttatcgaagaatggaaaaaatctcacaatataaagcacgtaggtcttatcacatgcaaggcatttggtttatacaaatccattaatgtggaatatcgattcttggtaataaatagattaggtgcagatctagatgcggtgatcagagccaataataatagactaccagaaaggtcggtgatgttgatcggaatcgaaatcttaaataccatacaatttatgcacgagcaaggatattctcacggagatattaaagcgagtaatatagtcttggatcaaatagataagaataaattatatctagtggattacggattggtttctaaattcatgtctaacggcgaacatgttccatttataagaaatccaaataaaatggataacggtactctagaatttacacctatagattcgcataaaggatacgttgtatctagacgtggtgatctagaaacacttggatattgtatgattagatggttgggaggtatcttgccatggactaagatatctgaaacaaagaattctgcattagtaagtgccgcaaaacagaaatatgttaacaatactgcgactttgttaatgaccagtttgcaatatgcacctagagaattgctgcaatatattaccatggtaaactctttgacatattttgaggaacccaattacgacgagtttcgtcgagtattaatgaatggagttatgaaaaatttttgttgataaaaaaattaaaaaaataacttagttattatcactctcgtgagtacaatagaaacatggcgatgttttacgcacacgctttcggtgggtacgacgagaaccttcatgcatttcctggaatatcatcgacggttgccaatgatgtcaggaaatattctgttgtgtcagtttataataaaaagtataacattgtaaaaaacaaatatatgtggtgtaacagtcaagtgaacaagagatatattggagcactactgcctatgtttgaatgcaatgaatatctacaaattggagatccaatccatgatctagaaggaaatcaaatctctattgtcacatatcgccacaaaaactactatgctctaagtggaattgggtacgagagtctagacttgtgtttggaaggagtagggattcatcatcacgtacttgaaacaggaaacgcggtatatggaaaagttcaacatgagtattctactatcaaagagaaggccaaagaaatgaatgcactcaaaccaggacctatcatcgattaccacgtctggataggagattgtgtctgccaagttactactgtagacgtgcatggaaaggaaattatgagaatgagattcaaaaggggtgcggtgcttccgattccaaatctggtaaaagttaaagttggggaggaaaatgatacaataaatctttccacttccatatcagctctcctaaattccggtggcggcaccatcgaggtaacatctaaggaagaacgtgtagattatgtactcatgaaacgtttggaatctatacatcatttgtggtctgtagtgtatgatcatcttaatgttgtgaatggcgaagaacgatgttatgtacatatgcattcatctcatcaaagtcctatgctgagtactgtaaaaacaaatttgtacatgaagactatgggagcatgtcttcaaatggactccatggaagctctagagtatcttagtgaactgaaggaatcaggtgggcggagtcccagaccagaattgcagaaatttgaatatccagatggagtgaaagacactgaatcaattgagagattggcagaggagttcttcaatagatcagaacttcaggccggtgaatcagtcaaatttggtaattctattaatgttaaacatacatctgtttcagctaagcaactaagaacacgtatacgacagcagcttccttctatactctcatcttttgccaacacaaagggtggatatttgttcattggagttgataataatacacacaaagtaattggattcacggtgggtcatgactacctcaaactggtagagagtgatatagaaaagtatatccaaaaacttcctgttgtgcatttctgcaagaaaaaagaggacatcaagtacgcatgtagattcatcaaggtgtataaacctggtgatgagactacctcgacatatgtgtgcgcaatcaaagtggaaagatgctgctgtgctgtgtttgcggattggccagaatcatggtacatggatactagtggtagtatgaagaagtattctccagatgaatgggtgtcacatataaaattttaattagggtaaggtaaaactatatataataactaacaatttgtgtatcatatagacaattaattaggtaactgttatctctttttaactaactaactaactaactaactcttatatactattaataatacatctattaatcattgattagcttattgctttaattgtttttgtaaactaacactgttcattgaaaagggataacatgttacagaatataaattatatatggatttttttaaaaaggaaatacttgactggagtatatatttatttcttcattacataacacgtctgtgttctaattcttccaattcttccacatctcatataatacaggaatataatcttgttcgaaaatatgagaaagtggataaaacaatagttgattttttatctaggtggccaaatttattccatattttagaatatggggaaaatattctacatatttattttatagatgctgctaatacgaatattatgattttttttctagatagagtattaaatattaataagaaccgtgggtcatttatacataatctcgggttatcatccattaatataaaagaatatgtatatcaattagttaataatgatcatctagataatagtataagactaatgcttgaaaatggacgtagaacaagacattttttgtcttatatattggatacagttaatatctatataagtattttaataaatcatagattttatatagatgccgaagacagttacggttgtacattattacatagatgtatatataactataagaaatcagaatcagaatcatataatgaattaattaagatattgttaaataatggatcagatgtagataaaaaagatacgtacggaaacacaccgtttatcctattatgtaaacacgatatcgacaacgcggaattgtttgagatatgtttagagaatgctaatatagactctgtagactttaatggatatacacctcttcattatgtctcatgtcgtaataaatatgattttgtaaagttattaatttctaaaggagcaaatgttaatgcacgtaatagattcggaactactccattttattgtggaattatacacggtatctcgcttataaaactatatttggaatcagacacagagttagaaatagataatgaacatatagttcgtcatttaataatttttgatgctgttgaatctttagattatctattgtccagaggagttattgatattaactatcgtactatatacaacgaaacatctatttacgacgctgtcagttataatgcgtataatacgttagtctatctattaaacagaaatggtgattttgagacgattactactagtggatgtacatgtatttcggaagcagtcgcgaacaacaacaaaataataatggatatactattgtctaaacgaccatctttgaaaattatgataccatctatgatagcaattactaaacataaacaacataatgcagatttattgaaaatgtgtataaaatatactgcgtgtatgaccgattatgatactcttatagatgtacaatcgctacatcaatataaatggtatattttaaaatgttttgatgaaatagatatcatgaagagatgttatataaaaaataaaactgtattccaattagttttttgtatcaaagacattaatactttaatgagatacggtagacatccttctttcgtgaaatgtaatattcttgacgtatacggaagttgtgtacgtaatatcatagcatctattagatatcgtcagagattaattagtctattatccaagaagctggatgctggagataaatggtcgtgttttcctaacgaaataaaatataaaatattggaaaactttaacgataacgaactgaccacatatctgaaaatcttataaacactattaaaatataaaatctaagtaggataaaatcacactacatcattgtttccttttagtgctcgacagtgtatactatttttaacactcataaataaaaatgaaaacgatttccgttgttacgttgttatgcgtactacctgctgttgtttattcaacatgtactgtacccactatgaataacgctaaattaacgtctaccgaaacatcgtttaatgataaacagaaagttacgtttacatgtgattcaggatatcattctttggatccaaatgctgtctgtgaaacagataaatggaaatacgaaaatccatgcaagaaaatgtgcacagtttctgattatgtctctgaactatatgataagccattatacgaagtgaattccaccatgacactaagttgcaacggtgaaacaaaatattttcgttgtgaagaaaaaaatggaaatacttcttggaatgatactgtcacgtgtcctaatgcggaatgtcaacctcttcaattagaacacggatcgtgtcaaccagttaaagaaaaatactcatttggggaatatatgactatcaactgtgatgttggatatgaggttattggtgtttcgtatataagttgtacggctaattcttggaatgttattccatcatgtcaacaaaaatgtgatataccgtccctatctaatggattaatttccggatctacattttctatcggtggcgttatacatcttagttgtaaaagtggttttacactaacggggtctccatcatccacatgtatcgacggtaaatggaatcccatactcccaacatgtgtacgatctaacgaagaatttgatccagtggatgatggtcccgacgatgagacagatctgagcaaactctcgaaagacgttgtacaatatgaacaagaaatagaatcgttagaagcaacttatcatataatcataatggcgttgacaattatgggtgtcatatttctaatctccattatagtattagtttgttcctgtgacaaaaataatgaccaatataagttccataaattgctaccgtgaatataaatccgttaaaataattaataattaataattaataacgaacaagtatcaaaagattaaagaattagctagaatcaattagatgtcttcttcagtggatgttgatatctacgatgccgttagagcatttttactcaggcactattatgacaagagatttattgtgtatggaagaagtaacaccatattacataatatatacaggctatttacaagatgcaccgttataccgttcgatgatatagtacgtactatgccaaatgaatcacgtgttaaacaatgggtgatggatacacttaatggtataatgatgaatgaattcgatactgtatgtgtgggtaccggactacgattcatggaaatgtttttcgattacaataaaaataatcccaaaaatagcatcaacaatcaaataatgtatgatataattaatagcgtagccataattctagctaatgagagatatagaagcgcgtttaacgacgatagaatatacatccgtagaactatgatggacaaattgtacgaatacgcatctctaactactattggtacgatcactggaggtgtttgttattttatctgttgatgcatctagttagtttgtataaataattatttcgatatactagttaaaattttaagattttaaatgtataaaaaactaataacgtttttatttgtaataggtgcagttgcatcctattcgaataatgagtacactccgtttaataaactgagtgtaaaactctatatagatggagtagataatatagaaaattcatatactgatgataataatgaattggtgttaaattttaaagagtacacaatttctattattacagagtcatgtgacgtcggatttgattccatagatatagatgttataaacgactataaaattattgatatgtataccattgactcgtctactattcaacgcagaggacatacgtgtagaatatctaccaaattatcatgccattatgataagtacccttatatccacaaatatgagggtgatgaacgacaatattctattaccgcagagggaaaatgctataaaggaataaaatatgaaataagtatgatgaacgatgatactctattgagaaaacatactcttaaaattggatttacttatatattcgatcgtcatgggcatagtaatacatattattcaaaatatgatttttaaaaatttaaaatatattatcacttcagtgacagtagtcaaataacaaacaacaccatgagatatattataattctcgcagttttgttcattaatagtatacatgctaaaataactagttataagtttgaatccgtcaattttgattccaaaattgaatggactggggatggtctatacaatatatcccttaaaaattatggcatcaagacgtggcaaacaatgtatacaaatgtaccagaaggaacatacgacatatccggatttccaaagaatgatttcgtatctttctgggttaaatttgaacaaggcgactataaagtggaagagtattgtacgggactatgtgtcgaagtaaaaattggaccaccaactgtaatattgactgaatatgacgatcatatcaatttgttcatcgagcatccgtatgctactagaggtagcaagaagattcctatttacaaacgcggtgacatgtgtgatatctacttgttgtatacggctaacttcacattcggagattctgaagaaccagtaacatatgatatcgatgactacgattgcacgtctacaggttgcagtatagactttgccacaacagaaaaagtgtgtgtgacagcacagggagccacagaagggtttctcgaaaaaattactccatggagttcggaagtatgtctgacacctaaaaagaatgtatatacgtgcgcaattagatctaaagaagatgttcccaatttcaaggacaaaatagccagagttatcacgagaaaatttaataaacagtctcaatcttatttgactaaatttctcggtagcacatcgaatgatgttacaactttttttagcattcttgactaaatattcataactaatttttattaatgatacaaaaatgaaataaactgtatattatacactggttaacgcccttggctctaaccattttcaagatgaggtccctgattatagtccttctgttcccctctatcatctactcaatgtctattagacgatgcgagaagactgaagaggaaacatggggattaaaaatagggttgtgtataattgccaaagatttctatcccgaaagaactgattgcagtgttcatcgcccaactgcaagtggaggattgataactgaaggcaatggattcagagtagttatatatgatcaatgtacagaaccccatgactttattatcaccgatactcaacaaacacgtcttggatcatctcatacatatattaaattcagtaacatgaatacaggtgtcccatctagtattccaaaatgttccagaactctctgtatttctgtatattgtgatcaagaggcgggagacataaaatttgaggagtatactcaagaatcaagtgatatcagtattagagttaagtatgattcatcatgtattgattatctgggtattaatcaaagtttcatgaatgaatgtattcgaagaattacaacatgggatagagaatcatgcgtcagaattgatacacagactataaataaatatcttaagtcttgcaccaacacaaaattcgaccgtaatgtctacaaaaggtacatactgaagagtaaagcactccatgctaaaacagagttgtaatagatataaaatactttttataataattaggctagaaaaatctcactcacatgtaatcttaaaaaaatgatatgatagttcttacaagtagcgattgagttttaaatggattctattaattaccggggaacttaacaattcgttctgatctacagacattggttaataaatcatcttattttgccaatatattaaaatgtggaaactccactaataatattacattgtgcgactttcaagatgatgtgatatatagggttatacagttttaacaattatataatagagatagaaagtacaaaagatgtagaatcaatgatatggcacgctaaacagttgggtgtggaatcattgctaaaagaatgtcaaaattatttgcttagaatattacgtatataattgtttagaaatttatagaataactaatattaatacattatcgtatatctacaacgatataagaaacttcatattggataatattactattaatatataaggatccagattttatatatttgcctaaatacattattatagatttactaggacaatcacctaaatgtttttaacgaagataatgtggtaaagattatatacacttatatatcttccgatatctacaaggatattccatatcatcattgtgtaaactaaataacgttttctatggcatttaataaggacattggatatgtggaaaagtgatgtatggaagttagtacattatcaacttctccttattgattgaaaatgaaaatataaatagtttttatgtatagcggtatctaccctatagttttattgcttactactaacatggattcagatacagatacagatacagatacagatacagatacagatacagatacagatgtagaagatatcatgaatgaaatagatagagagaaagaagaaatactaaaaaatgtagaaattgaaaataataaaaacattaacaagaatcatcccagtgaatatattagagaagcacttgttattaataccagtagtaatagtgattccattgataaagaagttatagaatatatcagtcacgatgtaggaatatagatcatatctactaatttttataatcgatacaaaacataaaaacaactcgttattacatagcaggtatggaatccttcaagtattgttttgataacgatggtaagaaatggattatcggaaatactttatattctggtaattcaatactctataaggtcagaaaaaatttcactagttcgttctacaattacgtaatgaagatagatcataaatcacacaagccattgttgtccgaaatacgattctatatatctgtattggatcctttgactatcaacaactggacacgagaacgtggtataaagtatttggctattccagatctgtatggaattggagaaaccgatgattatatgttcttcattataaagaatttgggaagagtattcgccccaaaggatagtgaatcagttttcgaagcatgtgtcactatgataaacacgttagagtttatacactctcaaggatttactcatggaaaaatagaaccgatgaatatactgattagaaataaacgtatttcactaattgactattctagaactaacaaactatacaaaagtggaacacatatagattacaacgaggacatgataacttcaggaaatatcaattatatgtgtgtagacaatcatcttggagcaacagtttcaagacgaggagatttagaaatgttgggatattgcatgatagaatggttcggtggtaaacttccatggaaaaacgaaagtagtataaaagtaataaaacaaaaaaaagaatataaacaatttatagctactttttttgaggactgttttcctgaaggaaatgaacctctggaattagttagatatatagaattagtatacatgttagattattctcaaactcctaattatgacagactacgtagactgtttatacaagattgaaattatattcttttttttatagagtgtgggggtagtgttacggatatctaatattaatattagactatctctatcgcgctacacgaccaatatcgattactatggatatcttcagggaaatcgcatcttctatgaaaggaaagaatgtattcatttctccagcgtcaatctcgtcagtattgacaatactgtattatggagctaatggatccactgctgaacagctatcaaaatatgtagaaaaggaggagaacatggataaggttagcgctcagaatatctcattcaaatccatgaataaagtatatgggcgatattctgccgtgtttaaagattcctttttgggaaaaattggcgataagtttcaaactgttgacttcactgattgtcgcactatagatgcaatcaataagtgtgtagatatctttactgagggaaaaatcaatccactattggatgaaccattgtctcctgatacctgtctcctagcaattagtgccgtatactttaaagcaaaatggttgatgccattcgaaaaggaatttaccagtgattatcccttttacgtatctccaacggaaatggtagatgtaagtatgatgtctatttacggcgagccatttaatcacgcatctgtaaaagaatcattcggtaacttttcaatcatagaactgccatatgttggagatactagtatgatggtcattcttccaaacaagattgatggattagaatccatagaacaaaatctaacagatacaaattttaagaaatggtgtaactctctgaaagctacgtttatcgatgtgcacattcctaagtttaaggtaataggttcgtataatcttgtggatacgctaataaagttgggactgacagatgtgttctattcaactggtgattatatcaatatgtgtaattcagatgtgagtgttgacgctatgattcacaaaacgtatatagatgtcaatgaagagtatacagaagcagctgcagcaacttctgtactagtggcagactgtgcatcaacagttacaaatgagttctgtgcagatcatccgttcatctatgtgattagacatgtcgatggtaaaattcttttcgttggtagatattgctctccaacaactaattaagcacattcttaatattagaatattatatagttaagatttttactaacaggttaacatttttttttaaaaatagaaaaaacatgtggtattagtgcaggtcgttattcttccaattgcaattggtaagatgacggccaactttagtacccacgtcttttcaccacaacactgtggatgtgacagactgaccagtattgatgacgtcagacaatgtttgactgaatatatttattggtcgtcgtatgcataccgcaacaggcaatgcgctggacaactgtatgacacactcctctcttttaaagatgatgcggaatcagtgttcatcgacgttcgtgagctggtaaaaaatatgccgtgggataatgttaaggattgtacagagatcatccgttgttatataccggatgagcaaaaaaccatcagagagatttcggccatcattggactttgtgcatatgctgctacttactggggaggtgaagaccatcccactagtaacagtctgaacgcattgtttgtgatgcttgagatgctcaattacatggattataccatcatattctggcgtatgaattgatgagttacagcttgacatttcttctttcctccctcttcttctacctttcccagaaacaaactttttttacccactataaaataaaatgagtatactacctgttatatttcttcctatatttttttattctccattcgttcagacttttaacgtgcctgaatgtatcgacaaagggcaatattttgcatcattcatggagttagaaaacgagccagtaatcttaccatgtcctcaaataaatacgctatcatccggatataatatattagatattttatgggaaaaacgaggagcggataatgatagaattatacagatagataatggtagcaatatgctaattctgaacccgacacaatcagactctggtatttatatatacattaccacgaacgaaacctactgtgacatgatgtcgttaaatttgacaatcgtgtctgtctcagaatcaaatatagatcttatctcgtatccacaaatagtaaatgagagatctactggtaaaatggtatgtcccaatattaatgcatttatttctagtaacgtaaacacagaattatatggagcggacatcgacgccttagaaataagagacttaaacaacggacacctggaattattaccatagaagatgttagaaaaaatgatgctggttattatacatgtgttttagaatatatatatatatatatatatatatatatatatatatatatatgggcaaaacatataacgtaaccagaattataaaattagaggtacgggatagaataatacctcctactatgaaattaccagaaggagtagtaacttcaataggtagtaatttgactattgcatgtagagtatcgttgagacttcccacaacggacaccgacgtcttttggataagtaatggtatatgtattacgaagaagaagacgaggacggagacggtagaataagtgtagcaaataaaatctatatgaccgataagagacgtgttattacatcctggttaaacattaatcctgtcaaggaagaagatgctacaacgtttacgtgtatggcgtttactattcctagcatcagcaaaacagttactgttagtaaacgtgaatgtatgttgttacatttccatatcaattgagtttataagaattttttatacattatcttccaacaaacaattgacgaacgtattgctatgattaactcccacaatactatatatattattaatcattaacttgcagactatacctagtagtgctattttgacatactcatgttcttgtgtaatcgcagtatctatattattaaagtacgtaaatctagctatagttttattatttaattttagataatatactgtctccgtatttttaaaaaattaccacatcctttattaaatcatgaatgggaatttctgtgtcatcgttagtatattgtgaacaacaagagcagatatctataggaaagggtggaatgcgatacattgatctatgtagttttaaaacatacgcgaactttgaagaatttatataaatcatctcacgagatattgctctctgtcatattcatacacctgtataaactttctagacatcttacaatgtgttattttatgatcatatttacatatttactggtatatcaaagatgttagattagttaatgggaatcgtctataataatgaatattaaacaattataggaggagtttatacctacaaaaacatcataaaaatgagtcatcgtccgatttatgttttaaatatactaacattactaccttcagaaattatatacgaaatattatacatgctgacaattaacgatctttataatatatagtatccacctaccaaagtataattgtatttttctcatgtgatgtgtgtaaaaaactgatattatataattatcttagtacctatgatgaagatgaagatgaagatgaagatgatggtccgtatatattttgtatcattatcgttattgctattccatagttacgccatagacatcgaaaatgaaatcaccgaattcttcaataaaatgagagatactctaccagctaaagactctaaatggttgaatccagtatgtatgtttggaggcacaatgaatgatatggccgctctaggagagccattcagtgcaaagtgtcctcctattgaagacagtcttttatcgcatagatataaagactatgtggttaaatgggaaaggctagaaaagaatagacggcgacaggtttctaataaacgtgttaaacatggtgatttatggatagccaactatacatctaaattcagtaaccgtaggtatttatgtaccgtaaccacaaagaatggtgactgtgttcagggtgtagttagatctcatgtgtggaaaccttcttcatgcattccaaaaacatatgaactaggtacttatgataagtatggcatagacttatactgtggaattctttatgcgaaccattataataatataacttggtataaagataataaggaaattaatatcgacgattttaagtattcacaagcgggaaaggaattaattattcataatccagagttagaagatagtggaagatacgactgttacgttcattacgacgacgttagaatcaagaatgatatcgtagtatcaagatgtaaaatacttacggttataccgtcacaagaccacaggtttaaactaatactagatccgaaaatcaacgtaacgataggagaacctgccaatataacatgcagtgctgtgtcaacgtcattatttgtcgacgatgtactgattgaatgggaaaatccatccggatggattataggattagattttggtgtatactctattttaactagtagaggcggtatcaccgaggcgactttgtattttgaaaatgttactgaagaatatataggcaatacatatacatgtcgtggacacaactattattttgataaaactcttacaactacagtagtattggagtaaatacacaatgcatttttatatacattactgaattattattattaattatatcgtatttgtgctatagaatggatgaagatacgcgactatctaggtatttgtatctcaccgatagagaacatataaatgtagactctattaaacagttgtgtaaaatatcagatcctaatgcatgttatagatgtggatgtacggctttacatgagtacttttataattatagatcagtcaacggaaaatacaagtatagatacaacggttactatcaatattattcatctagcgattatgaaaattataatgaatattattatgatgattatgatagaactggtatgaacagtgagagtgataatatatcaatcaaaacagaatacgagaatgaatatgaattctatgatgaaacacaagatcaaagtacacaactagtagattacgacattaaactcaaaaccaatgaggatgattttgttgatgaattctatggttatgatagatcagtgggtgtccatgattatatagatgtatcaattaataaagtagtatatggaagagagtctcacgtaagatggtgggatatatggcaagaacataatgatggcgtatacagtataggaaaggagtgcatagataatatatacgaagacagacataccgtagacgaattctacaagatagacagcgtatcagatgtagatgacgcagaacatatatctcagataactaatgatgtatctacacaaacatgggaaaagaaatcagagttagatagatacatggaaatgtatcctcgtcatagatatggtaagcattctgtctttaagggattttctgacaaagttagaaaaaatgatttagacatgaacgtggtaaaagaattactttctaacggtgcatctctaacaatcaaggatagcagtaataaggatccaattgctgtttattttagaagaacaataatgaatttagaaatgattgatatcattaacaaacatacaactatctatgaacgcaggtatatagtacactcctatctaaaaaattatagaaatttcgattatccatttttcagaaagttagttttgactaataaacattgtctcaacaattattgtaatataagcgacggcaaatatggaacaccactacatatattagcatctaataaaaaaataataactcctaattacatgaagttattagtgtataacggaaatgatataaacgcacgaggtgaagatacacaaatgcgaactccattacacaaatatttgtgtaaatttgtatatcataatattgaatatggtatccgatactataatgaaaagattatagacgcatttatagagttaggagccgatctaactattccaaatgacgatggaatgataccagtagtttactgtatacactcaaatgccgaatatggttataacaatattactaacataaagataatacgtaaactacttaatcttagtagacatgcgtcacataatctatttagagatcgagtcatgcacgattatataagtaatacatatattgatcttgagtgtttagatatcattagatcacttgatgggtacgatattaattgttactttgaaggacgtacaccacttcattgcgctatacaatataacttcactcagattgctgagtacttattagatcgaggagctgatatatcattaaagacagacgatggtaaaactgtatttgatttatcgttatgtagttacattcctcttaaatggactagctttttgattagtcgtctaccgcctaaaagtgtcatatgctcactgactaaccatataatagattatgttcttacgaacaatagacgtattatttggcagagtcaaatgattaataagtacgtactgttactggacccatccttttattatagattcagaaatgttatcgaaaacaaattagaccaatacaataatcgttataatatgttcgaacacgatagggacgttaatgaaaagtatggcaaagtcttacatgacctcgatacatatatcaaggatgtacaagtattaaaatctacttccatcactaataatataacactatacgacactattataaataataagtcagagtttcctatacgtcgtgtaaacgacaaacaattaattaatctcataaaatccaatacatatcataatcttatcgaaaaagttattaaaaatacattagagaaatatactttaactaatatagtcctcgagtatatgatctcatctcgatctcaatcatcttatttgagtcgtattcctaatgagatattactcgaaatattatataaactcgacatgtacgatttacgtaatctatatacaagatatatgagagagaatgatatcacagagtatcatatagagaatacgaggtctgtttctacacagacatgaataatgaatacacatacaacgttttttttaatcttagatataacactaattacatcaagattatatattgaaatcgtaatttgagttgtctgatcatcatggatatcgaaaataatatacgtaacattagcaatcttttagatgattgatatattattatgcgatgtaatcataactatcggagatgtagaaattaaagcgcataaaactattttggttgccggatctacgtattttaaaacaatgttcacaacatctatgatagcgagagatctagcaactagagtaaatatacagatgttcgataaagatgccgtcaaaaatattgtacagtacttatacaataggtatataagttctatgaatgtgatagacatattaaaatgcaccgactaagaacgtaaaacgaactatagaatgttatacaatgggtgatgataagtagaagatgttacccgatatacccatagcattatctagttatggcatgtgtgtattagatcaatacatatacattataagcggtcgtacccaacactgattatacatcggtacatacagtaaatagcatagatatggaggaggatacaaatatttcaaataaagttatgagatacgcgctgtcaataatatatggaagacattacctaacttctgaactggaactataaatccaggctctcgcataaagatgaatatatatgttgtatgcgacatcaaagatgaaaaaatgttaagacttatatatttagatataacacgaatatgtatgacggatgggaattggtaacgatgacagaaagcagattgtcagctctgcatactattcttcatgacaataccataatgatgttacattgttatgaagcgtatatgttacaagatacatttaatgtgcttacggaacatatatttagaaacatctactaacgattttttatgcttgtattattaatggtatgtaatatgatttaattgattgtgtacacgataccaatttgtcgagtatgaatacggagtacaaacataaactgaagtttaacattatttatttatgatatacattatatacattatatacattatatacattatatacattatatacattatatacattatatacattatatacattatatacattatatacattatatacattatatacattatatacattatatacattatatacattatatacattatatacattatatatcgttattgtttggtctatgccatggatatctttaaagaactaatcttaaaacatacggatgaaaatgttttgatttctccagtttccattttatctactttatctattctgaatcatggagcagctggttctacagctgaacaactatcaaaatatatagagaatatgaatgagaatacacccgatgataagaaggatgacaataatgacatggacgtagatattccgtattgcgcgacactagctaccgcaaataaaatatacggtagtgatagtatcgagttccatgcctcattcctacaaaaaataaaagacgattttcaaactgtaaactttaataatgcgaaccaaacaaaggaactaatcaacgaatgggttaagacaatgacaaatggtaaaattaattccttattgactagtccgctatccattaatactcgtatgatagttattagcgccgtccattttaaagcaatgtggaaatatccattttctaaacatcttacatatacagacaagttttatatttctaagaatatagttaccagtgttgatatgatggtgggtaccgagaatgacttgcaatatgtacatattaatgaattattcggaggattctctattatcgatattccatacgagggaaactctagtatggtgattatactgccggacgacatagaaggtatatataacatagaaaaaaatataacagatgaaaaatttaaaaaatggtgtggtatgttatctactaaaagtatagacttgtatatgccaaagtttaaagtggaaatgacggaaccgtataatctggtaccgattctagaaaatttaggacttactaatatatttggatattatgcagattttagtaagatgtgtaatgaaactatcactgtagaaaaatttctacatacgacgtttatagatgttaatgaggagtatacagaagtatcggccgttacaggagtattcatgactaacttttcgatggtatatcgtatgaaggtctacataaaccatccattcatatacatgattaaagataacaccggacatacactttttatagggaaatactgctatccgcaataaatataaacaatagacttttatcacgttatctcatgtataaaatattacaaatagtatagcataaactaaagtcgatacatacattaaaacttaaataataatgtaatttacaattaatagtataaactaaaaaaattaaaaaattaaaaacaatatcattattataagtaatatcaaaatgacgatatacggattaatagcgtatcttatattcgtgacttcatccatcgctagtccactttacattcccgttattccgcccatttcggaagataaatcgttcaatagtgtagaggtattagtttctttgtttcccgatgaccaaaaagactatacagtaacttctcagttcaataactacactatcggtaccaaagactggactatcaacgtactatccacacctgatggtctggacataccattgactaatataacttattggtcacggtttactataggtcgtgcattgttcaaatcagagtctgaggatattttccaaaagaaaatgagtattctaggtgtttctatagaatgtaagaagccgtcgacattacttacttttttaaccgtgcgtaaaatgactcgagtatttaatagatttccagatatggcttattatcgaggagactgtctagaagccgtttatgtaacaatgacttataaaaatactaaaactggagagactgattacacgtacctctctaatggggggttgcctgcatactatcgtaatggggtcgatggttgattattgattagtatattccttatattccttattctttttattcacacaaaaagaacatttttataaacatgaaaccactgtctaaatgtaattatgatcttgatttatagatgatgatcagccttcagaggattttgaccagtatgtttaatatgaaaaaaaacataactattaagcgctattgcgctattgtgcttaattattttgctctataaactgaatatatagccacaattattgacgggcttgtttgtgaccgacaatcatgaattttcagaaattatctctggctatatatcttacggtgacatgttcgtggtgttatgaaacatgtatgagaaaaactgcgttgtatcatgacattcaattggagcatgtagaagacaataaagatagtgtagcatcgctaccgtacaagtatctacaagtagtcaaacaaagagaacgtagtagattgttggctacatttaattggacggatatagctgagggtgttagaaatgagttcattaaaatatgtgatatcaacggaacatatctatataattatactattgctgttagtataattattgattccacggaagaactaccaacagttactccaattacaacatatgaaccttctatatataattatactatcgattatagcactgttattactactgaagaactacaagtgactccaacatatgcacctgtaacaactcctcttccaacatcagcagttccttatgatcaacgatcgaataacaatgtaagtactatatctattcaggtactgagtaaaatattgggagtcaatgaaacagaattaactaattatcttattatgcataaaaatgacactgttgacaataacaccatggttgatgatgagacatctaacaataacacattacatggtaatataggatttttggaaataaataattgttataatgtttctgtgtcagatgctagttttagaataacattagtaaacgatacttctgaagaaattttgctaatgctaacaggaactagttcatccgacaccttcatatcttccaccaatatcactgaatgtttgaaaacattaatcaataatgtgtcgattaatgatgtacttataacacaaaatatgaatgtaacatctaattgtgataaatgctcaatgaatttgatggcatccgttattcctgcagttaatgaatttaacaatacgttgatgaaaattggtgtaaaagatgatgaaaacaatacggtatataaatattataattgtaaactaactacaaattctacatgtgatgagttaatcaatttagatgaagtcattaacaacataactctgacaaatattatacacaatagtgtttcgacaactaacagcagaaaaagacgagatctgaatgatgagtttgaattttccacttccaaggaattagattgtctttacgaatcatatggtgtaaacgatgatataagtcattgttttgcatcacctagacgtagacgatctgacgacaaaaaggagtacatggacatgaaattattcgaccacgcgaaaaaagatttaggaatagacagtgttattcctagaggtacaacccatttccaagtaggtgcatctggtgcaagtggtggtgttgtaggagatagtttcccatttcaaaatgttaaatcgcgtgccagtctattggcggaaaaaataatgcctagagtacctattactgctaccgaagctgatctatatgcaactgtaaatagacaacccaagttaccagcaggtgttaaaagtactccgtttacagaggcgcttgtgtctacgataaaccaaaagctttctaatgttagagaggtaacttatgcttcgctcaatctgccaggatcaagtggctatgttcatagaccatctgattctgttatttatagcagtataagacggtcacgtttacctagtgatagcgatagtgattatgaggatatacaaactgttgttaaggaatataatgaaagatatggtagatcagtcagtagaacacagtcatcaagtagtgaaagcgattttgaagatatagatactgttgttagggaatatagacaaaaatatggcaatgcaatggcaaaaggacgtagtagttcccctaaacctgatccattatatagtactgttaagaaaacaactaaaagtctatctactggtgtagacatagttacaaaacaatcagactattctctattacctgacgttaatactggcagttctattgtgtcacctctcaccagaaaaggagctactagacgacgacctagacgccctacaaatgatggtctacagagtccaaatcctcctctccgtaatccacttcctcaacatgatgattattctcctccacaagtacacagacctccaccacttcctcctaaaccagtccaaaattcgccacaacttccccctagaccagtaggtcaattactacctcctcctatagatcaaccagataaaggatttagtaagtttgtatcacctagacggtgtagaagagcaagctctggagtcatatgtggtatgatacaatcaaaaccaaacgatgatacctattcacttcttcaacgatcaaaaattgaaccagaatatgtggaggttggtaatggtatacccaagaacaatgttcctgtaataggtaataaacatagtaaaaaatatacatcgacgatgtcaaaaatatcaacaaaatttgataaatctacggcatttggagcagcaatgttactaactggtcagcaggccattagccaacagactagatcaactacgttgagtagaaaagatcagatgagtaaggaagaaaagatattcgaagcagttacaatgagtctatcaactataggttcaacgttgacgtctgcaggtatgacgggtggtccaaaactaatgattgcaggaatggctataacggctataactggtataatagatacgataaaagatatatattacatgttttcaggacaggagaggccagtagatcctgttattaaattatttaataagtacactggcttaatgtccgataataataaaatgggtgtaagaaaatgtttgacacccggtgacgacacacttatttatatcgcatacagaaacgataccagttttaaacagaatacggatgcgatggctttgtatttcttagatgttatcgattcagagatcctatatctaaacacatcaaatttagttctagagtatcaactaaaggtggcttgccccataggaacattaagatctgtagatgtggacataactgcgtatacaatattatatgatacagcggataatattaagaaatacaagtttatcagaatggcaacgctactatccaaacatccagttattagattgacatgtggtttagcagcaacattggtgattaaaccgtacgaggtacccatcagtgatatgcaactactaaaaatggcgacgcctggtgaaccagaatccactaaatctataccatccgatgtctgtgataggtatcctctaaagaaattctatcttttagctggtggttgtccctatgatacatctcaaacttttattgtacatactacttgcagtattctactaagaacagctacacgggatcagtttagaaacagatgggtgttacaaaatccatttagacaagaagggacatataagcaactgtttacctttagcaaatacgattttaacgacaccataatcgatcctaatggtgtggtgggtcatgctagcttttgtaccaatagaagcagcaaccaatgtttctggtccgaacctatgatattggaagatgtatcatcgtgtagttctagaactagaaaaatatacgtaaaactgggaatatttaatgctgaaggttttaatagttttgtactaaattgtccaactgggtctacacctacatacatcaaacataaaaatgcggacagtaacaatgttatcatagagctacctgtaggtgattacggcacagccaaattgtattcagcaacaaaaccatcgaggatagctgtgttctgcacacataactatgataaacgattcaaatcagatattatagttctaatgtttaataaaaacagcggtattccattttggagcatgtacacaggaagtgtaactagtaaaaatagaatgtttgccacattggctagaggaatgccgtttagatcaacgtattgcgataacagacgacgatcaggttgttattatgcaggaataccatttcatgaagatagtgtagaaacagatatacattatggaccagaaataatgttaaaggaaacatatgacataaacagtattgacccacgagttataacaaagtcaaagacccattttcctgctccattgagtgtaaaattcatggttgacaatttaggaaatggatatgacaaccctaattcattttgggaagatgctaaaactaagaaacggacatatagtgcaatgacgataaaagtcctaccatgtacagtgagaaataaaaatatagactttggatataactatggagatattatttctaatatggtttatctacaatctactagtcaggattatggagatggtaccaaatatacatttaaatccgtaactagatcagatcatgagtgtgaatctagcttagatctaacgtctaaggaagtaactgtgacatgtcctgcgtttagtataccaagaaatatatcaacatatgaaggtctatgctttagtgttactacatctaaagatcattgtgctacaggtattggttggttaaaatctagtggttatgggaaggaagatgctgataaaccacgtgcttgttttcatcattggaattattacacactgtcgttggattattactgttcatacgaagatatttggagaagcacctggcctgactatgatccatgtaagtcatatatccatatagagtatagagatacatggatagaatctaatgtgttacagcaacctccttacacattcgaattcattcatgacaattctaacgaatatgtggataaagaaattagtaacaaattaaatgatctgtacaatgaatacaagaagattatggaatatagcgacggatcattgccggcgtctataaacagattagcaaaggcattgacttcagagggtagagaaatagcaagtgttaatatagatggtaatctgttagatatcgcatatcaagcagataaggaaaagatggccgacatacagacaagaataaatgatattattagagatttgtttatacacactctatcagacaaagatataaaagacattatagaatccgaagaaggtaagagatgttgtataatagatgttaagaacaatcttgttaaaaagtactattctattgataattatctatgtgatactttagatgattatatatacacctctgtagaatataacaaatcctatgtgttagtaaacgatacttatataagctatgactatcttgaatcatcaggtgtagttgttctatcatgttatgaaatgactataatctccttggatacaaaagacgccaaagatgctatagaagatgtgatagtagcaagtgcggtagccgaagcattgaatgacatgtttaaggaatttgataaaaacgtaagtgctattataataaaagaagaagataattatctaaacagttcgcccgatatctaccatataatatatatcataggtggcactattctgctactgttagtcattattttaatattggcaatttatatagcgcgcaataaatacagaaccaggaaatatgaaataatgaaatatgacaatatgagcattaaatctgagcatcatgatagtcttgaaacagtgtctatggaaattattgataatcggtactaataaaatagtttaactcttttagaaccagtttggtactgtaatttcagttcattactcgttgagaatattgatgattttttttaaatgagtatcggtagttacatattaccatatcatccattatataatcgatgatgcatgtattagaatactttccgaataagtcttctaaatattgtattaattatgaaaaactatgctatgtgagtatgattcaaagatgtttaatgatacgatactagattttatctctagcgagattgtttagaatcatttatcataactatgtttaataaattcatcaacgaatatcgataaagacctcttgtaattcgagtataggaagtagtattaccatatcaacttccgagttaacaattactctaaaacatgaggattgtactcctgtctttattggagatcactatttagtcgttgataaactagtaacctcaggtttctttacaaacgataaagtacaacatcaagacctcacaacacagtgcaagattaatctagaaatcaaatgtaattctggaggagaatctagacaactaacacccacggcgaagtatactttatgcctcattcagaaacggtaactgtagtaggagactgtctctctaatctcgatgtatatataatatataccaatacggacgcgatatattccgacatgaatggcgtcgcttatcatatgttatatcctaaatgttgatcatattccacaaatgattgtgaacgagattaaatcatctaacaaataattagttttttatgacattaacatataataaataaattaatcattattgacttaacgatgacgaaagttatcattatcttaggattcttgattattaatacaaattcgttgtgtctatgaaatgtgaacaaggtgtctcatattataatgcacaagaattaaagtgttgtaaactatctagccaggaacatattcagattatcgatgtgataaatacagcgataccatctgtggacattgtccaagtgacacattcacgtcaatatataatcgttctcctcggtgtcatagttgtagaggtcacaccttgtacacctaccacaaatagaatatgtcattgtgactcgaatagttatcgtctccttaaagcttctgatggtaactgtgttacatgtgctcctaaaacaaaatatggtcgtgtgtacggaaagaaaggagaaaatgatatggaataccatttgtaagaaatgtcggaagggtacttattcagatattgtatctgactctgatcaatgtaaacctatgacaagataagacttactcgcatctactggatagacataaatatcctcctcgtaataatgaaatataatatacactaattattaatatcaatcgagtattaacatataagttatttttaaaccccttttgggttccgtcctaaacggcgtttcggtctgtgtcgccaccatggtcacaccgagcctctgcgtgctcctccatcgaggacgacttcaactatgacagctcggtggcgtctgccagcgtgtacatacgaatggcatttctaagaaaagtctacggtatcctttctacaatttcctttaacaacggcaacagctgcagtatttttatactttgaatgcatcggacatttatacaagggagtcctgttctaatattggcatcaatgttcggatctataggcttgattttcgcattgactttacacagacatgaacatcccctgaatctgtacatactttgtggatttacactgttagaatctctaacgctggcctctgttgttactttctatgatgcacgtatcgttatgcaagctttcatgttgactactgcagtgtttcttgctctgactacatatactctacaatcaaagagagatttcagtaaacttgtaacaggattgtttgctgctttctggattttaattttgtcaggagtcttgaggataaagtttaaaatagaattaataaagaacatataggtcattttttaaacatggatagaaaccaaggttgttagttaataatatacaagatattttttctcactctgatccatgtaaaccaaggacgagagacactctcattcctcattcacgacaccattaaaaatggaaattaaagccctctattaagcacagacggctacaggtctaccatcaggttaccttcgtctaccttcacaatggcctctccttgtgcccagttcagtccctgtcattgccacgctactaaggactccctgaataccgtgactgacgtcagacattgtctgactgaatacatcctgtgggtttctcatagatggacccatagagaaagcgcagggcctctctacaggcttctcatctctttcagaattgatgcaatggagctatttggtagcgagttgaaggagttctcgaattcacttccgtgggacaatatcgacaattgcgtggagatcattaaatgtttcatcagaaatgactccatgaaaaccgccaaagaactttgtgcaataattggactttgtactcaatcagctattgtcactggaagagtcttcaatgataagtatatcgacatactacttatgctgcgaaagattctgaacgagaacgactatctcaccctcttggatcatatcctcactgctaaatactaaatctccttcatgctctctcactaatactcttactcactacactttttatcatcttatgatgaatgattgccttcatcattttttcgtggaatataatataggaataattagcaccagaatagctatggatatctcgttaagaatattctctataagagacataatgtagacatagttattatatccttcttagataagtgttacgctactggaaagtttccatcgttattattacatgaagatgatataattaaaccaacattgagattggctcttatgttagctggattgaattactgtaataaatgcatcgagtatagagggatatagcaattctcgataatagtcatgcaatatttgaatgagactgataatttaggtaatacagtactacacacatatctttctagattatatatcgttaaaaatctgtaagatgtatatttctcataagtatccactgtgtaatattattaatggatatatagataacgcaatagggactaatagtattgtaaaagatataatcgactatttacgtacatatccagatatctatattcctactagtttgctgcgtagttgcatcattgatatgcatgatttatcaggattcagagatgaattactaagtaaactacaatcccacaataagtaagaatcaaatatcaaaaactcacttttgatttttctagtcttaagtaatacatatatttattaatagacctatgaaataaaaaaaggtaacaatggattcgcgtatagctatttacgtattagtatcggcatctcttttgtatcttgttaattgtcacaaactagtacattacttcaatctgaaaataaatggaagtgatataactaatacagcagatatattgctggacaattatccaattatgacctttgatggaaaggatatttatccatctatctcgttcatggtcggtaataaacttttcctagatctttataaaaatatctttgaagaatttttcagactatttcgagtatctgtaagtagtcaatacgaggaattagaatattattattcatgtgattatactaacaaccgtcctacaattaaacaacattacttttataacggcgacgaatatactgaaattgatagatcgaaaaaagccactaataaaaacagttggttaattacttcaggctttagactacaaaaatggttcgatagcgaagattgtataatttatctcagatctttagttagaagaatggaagacagtaacaaaaacagtaaaaaaacttagtacttagatatcgaaaaaatatatttttgtagactcttgagaatagaaggaaaacatgtacataattataaaaaatgaaaatcaatggcgaataagacagtgcgattcgcaccatggagtcggtagatttcatggctgtcgatgagcagtttcacgacgacctcgatctttggtcattatctttggtagatgattataaaaaacatggattaggtgttgactgttatgttctagaaccagttgttgacaggaaaatatttgatagatttctccttgaaccaatttgtgatcctgtagatgttctgtatgattattttaggattcatagagataatattgatcagtatatagtagatagactgtttgcatatattacatataaagatattatatctgcattagtgtcaaagaattatatggaagatattttctctataattattaagaattgtaattctgtgcaagatctcttactttactatctatctaatgcatatgtagaaatagacattgttgatcttatggtagatcatggggctgtaatatataaaatagaatgcttgaatgcctattttaggggaatatgtaaaaaggaaagtagtgttgttgagtttattttgaattgtggtatcccagatgaaaatgatgttaaattagatctatataaaataattcagtatactaggggattccttgtagatgaacccacagtattagaaatttataagctttgtatcccatatattgaagatatcaatcaactagatgctggtggaaggaccttgctttatcgcgctatctatgcaggttatatagatttagtatcatggctattagaaaatggagcaaatgtcaacgcagtaatgagtaatggatatacatgtcttgacgtggccgtggataggggatctgtcatcgcccgtagggaagcacatcttaaaatattagaaatattgcttagagaaccattgtctattgactgtataaaattagctatacttaataatacaattgaaaaccatgatgtgataaagctctgtatcaagtattttatgatggtagattattcactttgtaatgtgtatgcatcatcactctttgattatataattgattgtaaacaagaattggagtacattaggcagatgaaaattcataatacaaccatgtatgagttaatctataatagagacaaaaacaagcatgcttcccatattctacataggtattctaaacatccagttttgacacagtgtatcactaaaggattcaagatttacacagaagtaaccgagcaggtcactaaagctctaaacagacgtgctctaatagatgagataataaacaatgtatcaactgatgacaatctcctatcaaaacttccattagaaattagggatctaattgtttcacaagctgtcatatagagttctatccacccacctttcttgaaatgagttaatagtcataagttagttaagtcataagttagttaagtcataagttagttaagtcataagttagttaagtcataagttagttaagtcataagttagttaagtcataagttagttaagtcataagttagtttatagtctaacacttctaatttttataccttgatctttttctctaattatgaaaaagtaaatcattatgaagatggatgaaatggacgagattgtgcgcatcgttaacgatagtatgtggtacgtacctaacgcatttatggacgacggtgataatgaaggtcacatttctgtcaataatgtctgtcatatgtatctcgcattctttgatgtggatatatcatctcatctgtttaaattagttattaaacactgcgatctgaataaacgactaaaatgtggtaactctccattacattgctatacgatgaatacacgatttaatccatctgtattaaagatattgttacgccacggcatgcgtaactttgatagcaaggataaaaaaggacatattcctctacaccactatctgattcattcactatcaatcgataacaagatctttgatatactaacggaccccattgatgactttagtaaatcatccgatctattgctgtgttatcttagatataaattcaatgggagcttaaactattacgttctgtacaaattattgactaaaggatctgaccctaattgcgtcgatgaggatggactcacttctcttcattactactgtaaacacatatccgcgttccacgaaagcaattattacaagtcaaagagtcacactaagatgcgagctgagaagcgattcatctacgcgataatagatcatggagcaaacattaacgcggttacgaaaatcggaaatacgccgttacacacttaccttcaacagtataccaaacatagtcctcgtgtggtgtatgctcttttatctcgaggagccgatacgaggatacgtaataatcttaattgtacacccatcatggaatacataaagaacgattgtgcaacaggtcatattctcataatgttactcaattggcacgaacaaaaatacgggaaattacaaaaggaagaaggacaacatctactttatctattcataaaacataatcaaggatatggaagtcgctctctcaatatactacggtatctactagatagattcgacattcagaaagacgaatactataatacaatgactcctcttcataccgccttccagaattgcaataacaatgttgcctcatacctcgtatacattggatacgacatcaaccttccgactaaagacgataagacagtattcgacttggtgtttgaaaacagaaacattatatacaaggcggatgtcgttaatgacattatccaccacagactgaaagtatctctacctatgattaaatcgttgttctacaagatgtcggagttctctccctacgacgatcactacgtaaagaagataatagcctactgcctattaagggacgagtcatttgcggaactacatactaaattctgtttaaacgaggactataaaagtgtatttatgaaaaatatatcattcgataagatagattccatcatcgaaaaatgtagtcgtgacataagtctcctcaaagagattcgaatctcagacaccgacttgtatacggtattgagaacagaagacattcggtatcacacatatctcgaagccatacattcagacaaacgcatttcatttcccatgtacgacgatctcatagaacagtgtcatctatcgatggagcataaaagtaaactcgtcgacaaagcactcaataaattagagtctaccatcgatagtcaatctagactatcgtatttgcctccggaaattatgcgcaatatcataaccaagctaagcgactaccatctaaacagtatgttgtacggaaagaaccattacaaatattatccatgatagaaagaaaatatttaaaaaataatctatatgattggagaagtaggaaacaaacagtaacaagacgacgattactacattattaaatcatgaggtccgtattatactcgtatatattgtttctctcatgtataataataaacggaagagatatagcaccacatgcaccatccaatggaaagtgtaaagacaacgaatacagaagccgtaatctatgttgtctatcgtgtcctccgggaacttacgctttcagattatgtgatagcaagactaatacacaatgtacaccgtgtggttcggatacctttacatctcacaataatcatttacaggcttgtctaagttgtaacggaagatgtgatagtaatcaggtagagacgcgatcgtgtaacacgactcacaatagaatctgtgaatgctctccaggatattattgtcttctcaaaggagcatcagggtgtagaacatgtatttctaaaacaaagtgtggaataggatacggagtatccggatacacgtctaccggagacgtcatctgttctccgtgtggtcccggaacatattctcacaccgtctcttccacagataaatgcgaacccgtcgtaaccagcaatacatttaactatatcgatgtggaaattaacctgtatccagtcaacgacacatcgtgtactcggacgaccactaccggtctcagcgaatccatctcaacgtcggaactaactattaccatgaatcataaagattgtgatccagtctttcgtgcagaatacttctctgtccttaataatgtagcaacttcaggattctttacaggagaaaatagatatcagaatacttcaaagatatgtactctgaatttcgagattaaatgtaacaacaaagattcatcttccaaacagttaacgaaaacaaagaatgatactatcatgccgcattcagagacggtaactctagtgggcgactgtctatctagcgtcgacatctacatactatatagtaataccaatactcaagactacgaaaatgatacaatctcttatcatatgggtaatgttctcgatgtcaatagccatatgcccgctagttgcgatatacataaactgatcactaattcccagaatcccacccacttatagtaagtttttttacctataaataataaatacaataattaatttctcgtaaaagtagaaaatatattctaatttattatatggtaagaaagtagaatcatctagaacagtaatcaatcaatagcaatcatgaaacaatatattgtcctggcatgcatgtgcctagtggcagctgctatgcctactagtcttcaacaatcttcatcctcgtgtactgaagaagaaaacaaacatcatatgggaatcgatgttattatcaaagtcacaaagcaagaccaaacaccgaccaatgataagatttgtcaatccgtaacggaagttacagagaccgaagatgatgaggtatccgaagaagttgtaaaaggagatcccaccacttattacactatcgtcggtgcgggtcttaacatgaactttggattcaccaaatgcccaaagattttatccatctccgaatcctctgatggaaacactgtgaatactagattgtccagcgtgtcaccgggacaaggtaaggactctcccgcgatcacgcgtgaagaagctctggctatgatcaaagactgtgagatgtctatcgacatcagatgtagcgaagaagagaaagacagtgacatcaagacccatccagtacttgggtctaacatctcacataagaaagtgagttacaaagatatcatcggttcaacgatcgttgatacaaaatgtgtcaagaacctagagtttagcgtacgtatcggagacatgtgtgaggaatcatctgaacttgaagtcaaggatggattcaagtatgtcgacggatcggcatctgaaggtgcaaccgatgatacttcactcatcgattcaacaaaactcaaagcatgtgtctgaatcgataactctattcatctgaaaatggatgagttgggttaatcgaacgattcagacaccgcaccacgaattaaaaaagaccgggcactatattccggtttgcaaaacaaaaatatttaactacattcacaaaaagttacctctcgttacttcttctttctgtttcaatatgtgatacgatatgatcactattcgtattctcttggtctcataaaaaagttttacaaaaaaaaaaaaaaaaatatttttattctctttctctcttcgatggtctcacaaaaatattaaacctctttctgatgtctcaactatttcgtaaacgataacgtccaacaatatattctcgtagagcttatcaacatccttataccaatctaggttgtcagacaattgcatcataaaataatgtttataatttacacgttaacatcatataataaacgtatatagttaatatttttggaatataaatgatctgtaaaatccatgtaggggacactgctcacgttttttctctagtacataatttcacacaagtttttatacagacaaattaattctcgtccatatattttaaaacattgacttttgtactaagaaaaatatcttgactaaccatctctttctctcttcgatgggtctcacaaaaatattaaacctctttctgatggagtcgtaaaaagtttttatcctttctctcttcgataggtctcacaaaaatattaaacctctttctgatggtctctataaacgattgatttttcttaccctctagagtttcctacggtcgtgggtcacacatttttttctagacactaaataaaatagtaaaat diff --git a/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/sequences.fasta b/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/sequences.fasta new file mode 100644 index 00000000..40dd888e --- /dev/null +++ b/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/sequences.fasta @@ -0,0 +1,18 @@ +>MPXV_USA_2022_MA001 | ON563414.2 +TATTATATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCRAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTTGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGAGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGAGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATATAATA +>Monkeypox/PT0001/2022|sampling_date_20220504_v2 +CGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGNAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACNTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTNAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACNGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCNTTTGAGAAGACAATAATATCCTNGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTANGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACNGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTNAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAANNGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTANGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCNNNTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTANCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTAACTAACTTATGANTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAANACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATANTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATNAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATNAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATNCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCNAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTNNAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATNAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCNTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATNAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTANTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCNTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCNNTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCNGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTNNTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTNGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCANTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTNAATACATCTATATTANGATTTGATGTTGTCGCGTANTNNTCTACAATATTAATACCANTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTNAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAANNNATTNATATTTTTATAGTCGACTGACGACAATAACAAAATNACNACATCNTTTTTGANNNNNNNNNNNTTTNNNNTAACGTATGCCTTTNNTGGANNNTCACCATCATACNCNNATAATGGATTTGCACCACTTTCTATTAATGATTNTNNACTACTGGCANCGATGTTAAATGNNTTACAACTATCATAGNGTATNNTATCGTTAACCATGATTGGTTGTTGATGTTATCACANNTTTTTGGTNNNTTTCATTTCAGNTANNTATGGATTTAGCACGTTTNGGAAGCANGNGCTCNNATGATTTCAGTACTGTAGTGTCAGTNNTATTAGTTTCGNTCAGATCAATGTCTAGATCTATAGAATCNAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCNTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTAGTATAAAATTCTATATTCAAATTATCATGCGANNTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAANNAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGNTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCNTGTAATCATTCGAAATAANTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGNGGAATCAGTTANGAANAAAAAATTATCTGTCATCATCATCATCTATTNGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTNGATACATCACGACCNTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCNTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAANTTTTTATGGTATAGATCCNNTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTANCTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCNTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTNGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATNAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTANGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTANGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCNAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCNAATACTTNGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAANNAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAANCNGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTNGATCTGCGCNGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCNAAACAACATATACACATTTAATNAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTANGAGCCATCATTTCGGCTATCGACTTAATATNCCTCTTGTTTTCGATAGAAAATCTANNGAGNTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGNGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCNTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGNAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTNAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATNCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCNTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGNAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAANTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCNTTTTAAGCCAAAATATGGAAGCGAATGATCCGGNAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCNTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTNNTTCCACTGTCCAAAATGATGNCTCTGCCNTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAANTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTNCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTNNAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCNCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAANTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGNTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGNTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTNAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCNAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTNAAAAGTTGTCACAACAGGGTNGTTCGTAGATTTTANNGTATAACNGAGACATNNNTNNAAAGATAAACTTTNTGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTNNNTCGGTATCTACTTTATCTGCCGAATACAGTGCTNNNGNNAAAATTATAATNTTTNNNCTTTCGTATTCGTAATTNGTTCNCTTTTCATGTTCGNAAAAGTGAAACNTGCGGTTAAAATNGTTTATAACATTAATATTACTGTTNNNNNCTGNCGGATNAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTNNNNTCGTTAAACGCCTTTAGNAAAACTNNNGAAGAATATCTCAATGNGAGTTCCTGACCATCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTCATCTNCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCNNCGTAGTTTCCATGGGACTATANNNNNNTGTNNCCTNGAATNNNNNNTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCNNCCTGTAGATATGTGATNAAAATCGTCGTTTATAGGATAAANNCGTTTATCNNTTTGTTGNNNAAAGGATGAATTAATGTAATCATTCNNNTCTATCTTTAGTAGTGNTTCCNTATTAAAATTNTTAAAATAATTTAACAATCTAACTGACGGAGCCCNNNNTTNGTGTNAATCTAATTGGGACATTANNTTGTTAAAATATAAANNNTCTCCTAATATAACAGTATCTGATAANCTATNGGGAGNCATCCATTGATATTCANGGGATGAATCATTNGNAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCNTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTNCAATTGTTGCCTGTATTGTATTANAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTANGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCANTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAANCANNAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACNATGNNCGGNTTAATGTNNTATGTAACATTGAGTAAATNCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATNCAAACAATGTTTCTANCGGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNNCGAATCAGTAACTATGTTCANNTTTTTANNNGTANGACGTCTAGCCAGTATNGANNAGGATTTTCNAGATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTCTATGAGTTGTTNCAATAAATTATTTGTTGTGACTGCGTTCAAGNCATAAATTANNTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCNCTGATAGCAGTTTNAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCNTTTGTACCANTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTNAGAACATGTCTTCTATTCTNGAAAACGAAAACATCCTNNATNGACTCATTAAAACTTNTAACGNNCCNGNTTGTGTTTCNAATGCCTNNNNCAAGGANNTCAAGGATGCCATAGATNNTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGANTTTTTTATTAAATCAAATNGTCGGCTCTCTGGTTTACTACCCCAANGATAACAATAGTCTTGTAAAGATANNNNNNNNNNNNNNNNNNNNNNNNCCATCCAAATAANCCTANNANCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCNTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAANTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAANTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATANTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTNAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACANTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACNTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTANGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGNATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTNCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCNNNAAAAAATCNTTTTTNATTNNTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCNTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACNTATTCAGAGTTGTTGTTCAAATAGATNCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGNNNTGCGGACATTAAACGATTTGATGAGTTAGATATTAATNACNNNNATATATCTAATATAATTTATGAGGTGAACGATNNNACATTAGATACAATGGATGATATNAAGAAGTGTCAAATCNTTAACGAGGATACGNNGTATTATGTTAAGGAATACAATACATACCTGNTTTTGCACNAGTCNGATCCCATGGTCNNAGAGAACGGAATACTAAAGAAACTGTCATCNATAAAATCCAAGAGTAGACGGCTNNACTTGNTTAGCNAAAACATTNNNAANNNNTATTTNNACGGACAATTNGCTCGTCTAGGTCNNNTGTTNGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGNGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAANCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGNTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTNNAGAGATAATCTATATCATGTAGAAGAATTCTTNGATNAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTGATAAATGNNNACCGTTGCNACANNTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATANTTTAACCTGATGTNNTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAANNNGTAGGATATNAATATTATGGCCGCAACCGTTCCGCGNTTTGACGANNTGTANAAAAATGCACAAAGAAGAATTNTAGATCNAGNAACANNTTTNNGTAGAGGTCTNNNTAGACCGTTAATGNAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCNNTATAAANGTCCTATTNNCGTATATGAAGNAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTNCGGTAGATACGTATCATATCTTNNAAAGTTTTCNNNCCTTCCAACAAACGAGTTTATTANNNNNTTANTATTGACCTCCATCCCTATCTNNNATATCNTATTCTNGTTTNNAANNACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCNTGCGTTGGCTANGTATATACATCAAACAGGAGACTATNNGNCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTNGTCCCGTTCCAATAGGTATCNAAGATATAGATCACCCTAATCNTAGTAGAGCANNAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGNTTTTATTGNTTTACGTACCTGGGTATTCAATTACTACNNNNNNTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACNAAGAGCGACGTACAANTNTNNTAAATTATTTTATGCTTCNNAAAATGTAGGTCTTGAACCAAACATTCTTTGNAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATNGTTTNNAGNAAACTNNNTAAAATATTCTTTGATTGCTGCCGAGNTTAAAACTTNTATCGATAATTGTTTCNNNNGTTTTAATATTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAACCAAATACATATTANGGTTATCTGCGGATTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTATTAATCNGTCGTTCNAACTCCTTTGNTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCNGTNAACACNGAGTCGGTANNTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATNTCTATCGTCCATATAAAATGGATTACTTAATGTATTNGCNAACCGTAACATACCGTTNGATNNCTCNGNTCCATTTAGTACCNANNCNAGATACAATATCATTCTACGTCCTATGGANNTGCAACTCTTAGCCNAAGNGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTANNNTGNTTTAANNNNNTTTTATATNNNNNNNNNTNNNCCNAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTNNTGAAGCAAGAGTTGATTATTTATNNNTTCTTNCNATCTNTTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATNNNNNNNNNNNNNNNNNNNNNNNNNGATACAGACNNNTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGNTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCNNAGTATNGTCACCGATGAACGTCATTNNNNTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTNGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGANTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATNATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCNTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACANNNNNTCATTAATGANNGTAAACNNNAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGANCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTNAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGNTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATNTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTANTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCNAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTNGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACANTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGNAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATNTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTNCCCTGTCTGCAGCCATTTTTANGNTCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCNCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATNCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCNTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTNCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCNCAACATTNGAATAATACCGTTTGATATACCATTNGTACCNGAGATATAGCTTCCACTNGCACGAATATNNNTAATTGATAGACCTATTNCCCCTNCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCNATGCTATCATCGATCATGTTAAGTNGAAAACAGCTAGACATTTGGTGACGNGTNGTTNCCGCATTNAANAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAANTTTTAAAACCAAAATAGTTGTANGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCNGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTANNATGGCGGTGCCAGAAATTACCATCNAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTNNNTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTNNTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCNTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCNTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCNGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTNANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAATATTTCGATGATATACGGTAGTCTCTCNTTCNGACTTNTATAGCNTATTNCACAATACGAGTCATTATATACNCCNNAAAANNNAATNNNTAGTATNAAATCNGTATCGAATGGNNAAAACGAAATTATCGATATAGGNNTAGAANCNNGAACATTGAACGTATTAATACTTAATNNTTTTTCANNNNNAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTNNGACTTGATAGATATTAANGACGAATTGNAAATTANTTTTATNACCACNNGTGNNTCAGGANCNTNGTCGANNNCAGTTAACCAACCGAATGGAGTANNNNAAATATCATTAATATATGCNCTAGATATTAGTANNNNNNTTAANNCTTTGATTATCATCTNNTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGNNCATCCTCCNGAGTATTAATNGGTTTAGTAAACAGTCCANCGTTGCNATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCNNNCGNTTAAAGATNNNACCTCATCTAACGGAGACAANNTTNNNGTAGGNTTTNNAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACNTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCANTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGNAAAAGAATAGAAATNAAAATTATTATAATGGTGGAATTCAGTTNGAATATTGNCTCCNGAGTCATNAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTNCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACNTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCNTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGNGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGNAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTANGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCNAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCNAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGNAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTANTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCNTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACNTTTGTAGAATATTATTCNGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTNAAAATCAAAATCTAATGACCACATCNNTTTTTAGAGATGNAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGNAAAAANTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCNATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGNTTTGATCTACTATACTTTNAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTNCTTCGGCATTTCNNTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGANNCGTCTNNGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTANGGGTATACTTCNATAAGGTTTNTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTNGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGNGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTANNTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTANAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTNTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCNAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCNTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTNAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGNAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCNNGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCNGAAGTTAAAACTTTATCATCTNNTATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGNAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTNGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTNATTTGAATCCATCGATAGAAAAACANNTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTNGATAGATTTTTTNNANGATATCTTAGTGCNAAAGTATACATGTTAGAGAATATTCNAGTTATGAAAATAGNAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATNAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGNGTATTTNTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTANTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTNTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATANTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTNGCAACAATTGTAGATACCATTAATCACTGATTCCNNTTTCGATNNNGGACAATAGCACAATTGTTTAGCNNTNGACTCTANNTATNNAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATNAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTNTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCNTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTNCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAANCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACNGCACCCAATTGCTGTCGCACNTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGNTGATTTATTCGACTGGTGTCANGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTANNTCTCTTNNTNATATGGATACTAATTGTAGCTATTTAAATGNGTGCCGCANCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTNAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGNNAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTANNTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCNGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTANTAATCTTCTTTGGGCACATATACCAGTNTACCAGGTTCTNNNAACCTANTTACTGGTGCTCCTGTAGNATACNNNNNTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTANNACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGNAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCNGGGTTAATCTCACAACTTTACTGNTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATNCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCNGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCNAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTNAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGNAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATANTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGNAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATNCCACAGAACTAATGTATATTCTAGGTACTTNTGGACAACNNAGGATAGATNNNGAANCAGCAGAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATGGTTCTTCCAGGTGNCGCCAACANGGGNNANNTTAGTAAATTCNAGATTCCTATCTCTGACTATACGGGATATAACGACNTCAATCAAACNAAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTAGTTACGANNCAGAATCANTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTANNAGAGNNNCGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCNTAAAAAGTCAGAACCTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAANGAAACTATCTGATAAGATATCTTCTCNAAAGATCNAGGAGATAGNAGAAACNGNAGACNTTTAATTCTTATCNNNAACATANTTTTCNATGATCTGTCTTTTAAACGATNGATTTTNCACAAATGCGCCTCTCNANTCCCTCATAGAATGATNNACGNATNNANNNNATAGCATAGGTNATGANNCCTTATTTTTAGACATTAGATATNNNAAAATCATAGCCCNNCTTCTATTTACTNCTGCAACACAATGAACCAACACNGGCTCGNTTNGTTGATCACATNNNGANAAGAAGGCGGTCNCNTCGTCAAAANNNTTACTAATATCNGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATNNACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGNCAAGACATCAACACTTATANTTTTTGTTATTATATTGGCAATTAGTNNGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACNAGATATATGCGAATNAAAAATACNGTTAACGATTNNAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTNAAAAGGCGGCNAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCNAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCNANTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTNAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCNTTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATNCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTNAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACNTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTNAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAANTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACNTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTNNNNAAAAGATCNTNCAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATNAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATNCTATATATGNAAAAATAGCAACCNGTGTTTGATCATNCGCGTCAATATTCTGTTCTATCGTANTNTANAACAATCTTATATCNTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATANTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTNGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAANTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACNAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAANTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCNAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTNGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTNAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTNAGNTTNNATTATCTNNNGTACATGGTCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGATANNATAGTNNNNGNNAAGAAATCATTAGTGACGGAAAATCGTCTTCACNAAGAATGCTTGTTGAGACNATCAACAGAGGAACGTCATATNTTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAANTTTACGATAGACTTTAAGCTAAAATATTTTCTANGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCNCGCTATTAATCATCCNAAGTCAAGGCCTAATANATCTCTNGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTNTTTCTCCACCTATTAACGCACCTATAAAGACNTTTATGTTGCCTAAACAAGATATAGTAGGTCTNGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGNTACATCAAAAGGGTTGNATTGTTANTTTANACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTNAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTNGAGAGTCGTCTATCTTTATAGAGTATANNAAATTTACCAACGATANNNGCTTTNNNAAAGAATATGGTTCTNGTNNGATTGTGTNNTATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGNNATTNAGTNNGTTGTNGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCNAAGCATCAAAATAGGAGATGTCTTTANCGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGNAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCNNTAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCNNNGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCNANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAACNAAGTNNAAAGNTTATTANNNGCGCATCTACAATGGAAGATAGACCGTCTACAANAAACTTTTTCGAACTAAATAGAGGAGCCATTAAANNTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCNTTTCTNNNNNGTNAANAATANNATGGTATNGGTTCTGNTATNCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATNAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGNNATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCNAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTANTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTNNGAAATCACAATGACTTTATCAGATCNAAATTAACAAAATTAAANGAGCATGTANNTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTNAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTNGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATNGAAACAGCCGCTTAGAAATAAACGAGTANNTGTGTGTGGTATAGATCCGTATCCNAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACNAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTANGAGAAACAAAAAGTCACGCGATTTACTNGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATANGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGNAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTNGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAANCCTTGATAACNAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTNAAAAATATACNNGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGNAAAATAGAGAGCTGTATGNNAAAACATTATCTAGTTGNTTATGTGGTGCTACNNNANGATGTTTAACATTCNNNNTTGGAGAAACCGCAANNNNGAAGTCGACAACCAAACGTTTGTTAAAGTNNNCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAANTTTAACAGATGTATTNGANAAAGGACCTAATCCATTTATCGCTAATATGCATTTNNAAAGATCTGTANTCNGTAGNNNACNACCTGNTTTTGCATGTANNGGATCNAAGNNNNTTANATCNNNNNNNNNTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTNCAATAAAATTAATAATANAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATNAGAAGAATTGCCGTCGTGCGATTCAGAACACACNTTTCTCAACCTTCTGGTNNAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACNAAAAATATCATATTNCTATTATGAAACTATATCCTACACCGGAAGAGATTNCGGACTTTGCNTTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTNCNTTAATGACGGACCTCTNNNAAAAGGGATATATATTGTACGATAATGTGGTTANTCTTCCGTTGANTNCTNNNCAACAGAAAATATCCAAGTATTTTAATTNNNNNCTATTTGGNNACGATANNNANAGCTNNATCAATAGACATANGAANNNTNCCAATGTTAGTGATGAATATCTGCANNATATATTCATANNNGATANNTNATCTCCGTAAATATATGCCATATATTTATAGAATATATCACANATCTAAATGAATACCNGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGNTTATCTAGTTNGAANTATCATAGATGAGAACNGAAGCGTGTTATTGTTCCNNATTATNNGATCGGGTAAAACAATAATCGCTTTGTTGTTNNNCTTGGTAGCTTNCAGATTTNNAAAGGTTTACANTTTAGTANCGAACATCAACATCTTAAAAATTTTCAATTATAATATNGGTGTAGCTATGAACNTGTTTAATGACGAATTCATAGCTGNNNATATNNTTATTCATTCCACAACAAGNTTTTATTCTCTTAATTATAACGATAACGTNATTAATTATAACNGATTNNNNCNCTACAATAACTCTANTTTTATCGTTGATGAGGCACATNATATTTTTNGGAATAANNNNNNNGNACTTATGACCGTGATNNNAAATAAAAACAAGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTGAGATTATTAGTCGTGGTNNNNAAGNAATTCAGACACTTCTTAACGAACNCNGAGNGANNNTACNCNNNNATTTGNNTANNNNAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACNNNAGTAGTATATTGTCACATGTCTAAACNNCANNAGAAAGATTANNNGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATNAAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCACTTTNNNNNCTTCTNTAATTCNANATATGGTGGATTGGTAATTAAATATATCATGCTCNNNAATGGATATTCTGAATATAATGGTTCTCANGGNNCTAATCCACATATGATAAACGGCAAACCNAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTNTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCNTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCNTTGACATCNAAAANCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATAATTNTCGTATTAAGTATAACGACTNCAAGTTACTTNAAATGGTTACATCAGTTATAAAAAATAAANAAGACGCTANGAATTACATNNNNGATATTGTAAACGGTCACTTCTTTGTATCGAATNAAGTATTTGATAANNNNCTTTTATACAAATACGAAAACGATATTANTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTNGGGAGTTAANTNNNGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGNNATATAAAGAAATAAATGTCGAGCNTTGTTACCAATGGATATCTTCCAGTTACATTNGAACNNCATGAGNTGACGTTAGACATNAAAACTAATATTANGAATGCCGTATATAAGGCGTATNTCCATAGNNNAATNNGTGGTNAAATGGCCAAGNAAATAGAAATTCGTGAAGACGTGGAATTANNNNTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCNNNTGNANTAACCTACGCATATTATCACGTTNGGGATATAGTCAGAGGAACANNAAACATCGAAGATGAATCNAATGTAACTATTCANNNNNNAGATTTAANCTGTAAACTAAGTAGAGATTCNGGNACTGTATCATTTAGCGATTCNNAGTACNGNNTTTTTCGAAATGNNAANGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTNTCGCGAATATCGTTGACTNANAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTNCCTTCGATATATTTTTGATAATATGNAAAACATGCNNCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCNNATAATCTNCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTNTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCNGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTNGNAAAANTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACANTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGNTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAANCCTCCACTTATATATCCTCCTTTNAAATTAATCCTTACTAGTTTTCCAGTATTCTNGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCANAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGNGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTANTTNCNAGGATGACTNTCAAATTATTACNCNCACGGCANNNGNTAACCAATGCCTATNGTNTCANAAACNANTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGNAACAGACGAGATAGNTTTNTCTATTNNNAAATAATTAGAACTNNAAACATGTATNGAAAGNAACGATTATTTCTGAATTATTNCAATTATTTGAACAAACAGNNNNGAAGTATACTATCGTCANNTTTTTCTCNNGNTNCANNTACTGCTGATAATGATAGAATAAACGCNATTTATCCNNGTGGTATACCCAAAANNGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGNNAATATAGACANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAAGATACCATTATTAACAAANTTTTTGAGGTAATTTTCTTTGTTNGACGAATATNTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAANNTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTNAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATANTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCNTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCNTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCNGCGAGTTTAGCCNTTTGATAAATCTCTTCTTGCNTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTNCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGNTTTTTAACGCAATGGTCTTAGATNAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTNAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCNNGGATCTTNTATCAAAGCCNTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGNNNNNATATACAGTAGTCATTGNTTTACCGACACCTGNTTCATGGAACAATNAAAGAGAATGCATACTGTCTAATNCTNNGAAAACTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTNNACGGGCATATTAGTAGTTCTGCGTAAGGCATAANCGATATAGGCNNNNNGTGATTTACTCATTTATNNGNGNTNAGTAATAACTATGTTTTNAAAATCNNNNCAGTAGTTTNNCTAGNCTTNTCTNATGTNNNNTTTCGATACNTTTTGAATNNNAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTNGTATACTCTATTCGAAAACTCTAAGAACTTATTAATNAATTNCGTATCCACTGGATCGTTTNAAATNNTAAATTGAACAGTGTTCACATCCTTNCAAGACGAAGACTTAGTGNNGGACTTAACATGAGACATAAATNAATNCAAANTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCNTTCNNCCAACTANCGCNTACGCATTTTAACAGTCNAANANTTTTAAAGAGACTACAATATANTCTCNTNGTATCGATTNNACCTCTACCGAATAGAGTNGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAANGTTAACATCTTATAATCGCTAATGTATNGATTGNTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTNCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACNGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACANCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTNAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGNGAGTGCTTCTTCTTTANCGGGCTTAAAGACTGCTTTNNGTGCTGAAATAACCACATCTGGANNACTTACTNGCNNAGCCATTTAATTACGGAACTANTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACNAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGNTTTTTAGATCTCATATGTGCTNAAAAGTTTTCCCATACTAATTNGTTACTATTATTTTTCGTATANTTTTTAACAGTTTGAGGNTTTAGANTTTTAGTTACNGAAGTGATATCGAATATTTTATCCNAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCNAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCNTTTCTGTACTCNGATTCAGNTTNTCATCNTTTANNTGATTGATTATTTNAAAGACTAACTTATAANNCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGANNTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTNCAGAACATTGATGAGACAATAATCTCCGCAATACATTNNTCAAATGAATAAGTTTATTAGACACNNGGAAGNTTGNNNNNTTTTGTACCTTTGTACATTTTTGAAATACNGACTNNCNAAAAATACAATATTCATATCCTTGTTCAGATACNNTACCNNNATGTCTANAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTNCAATATTTTATATNAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATANTTTTANTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATNTTTTTCGTACCAACTCNTTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTANAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTANNTCNCGGATTGNAAACAGAAAGAGGATCGTACATCCAAGGTCCNTTTTCTGTAAATAGAATCGTATAATGTNCCTTCAAGAAGATATCNGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTANCCTATACATGATACCGTTTAGCNTGATTTCTGGTGATNCGTCAATCGGAGTATCATCTATNAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATANNCNTATTCTGANNTNNTTCTACATNAAACATCATTGCTCCATTAACGATAACANNNGAATGAACAGCNCTACCCATCACNNTAGTTCCCAATGGATCAANNTGTGTAACTNCAGAACATCTTCCATAGCCTATGTTANGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATNGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGNGTNCATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATNGGAAAGGAGTNGAAATNNCTCGNTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATNCTGAATAGTAAAGNTAGATNNNTCATACTTGTTAGTAGTTAGATATTNNGCAATTGNANTCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTACGTTTAGGTTTGGTACGTTGATTTCNANNCCCTGCTGATATNAAGTCATCGTCTACAATTTNGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAANNGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTNAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGANTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCNGNCTGAAGTTGACGCATATCNTTTTCAACACTNGACATGAGATCCNTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTNGATTTGGANTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGNNCATACAGTGGCCACAATANGAGGTTGAAGAGGTGTAACCGTTNGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCNTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTNGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATANGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTNCATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCNTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCANNNNNNNNNNNNNNNNNNNCATCCACGNTTTGATAAATCTATCNTTANCTNNTGAAATAACGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGATNACANNTTTTGTAAATGTAANGTANTTAGACGANAGATCTTCGTTNNAAAGTTTTNCATNTATNNNNAATNCATCGGTTGTTAACACCATTCCCGCGTCAGANTGAATANGAGTTTGAATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGATGNAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTNGAGGCCTCCGTAGAACTANGGGANGTAAATANAGATCNAACAACACCTATGATAAAGGAGAATANCGGNTTTATATCCCGTAGTNGNCGTCTATTNNCCCATANNNNTNNGGATNNNNNGANAAAACNNNCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAANTCAACTCNNNAGTATCCATCATCCAAGNAAAACNCGGATACCAGTCTNGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAGTTCANTATCTGAAATAACNNATAGATTTTATNNNNTTAATCNAAAATCTGATCTTGTTCAATGGNGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGNAAATGATTCACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAGCAAACGTGATNAGGATACGCTATTAAAACANTTTACTTATGACTGGNGTTAGAATTTATAGACGNNACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCNAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGANTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATNCTTCTNCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACNNNATGATTGTCTCAAGTCTNCAATCGTTTGTTTNGNNCGATTAGCTNCAGAGTNCAATGCTTGGCTAACTAGCATATTATTATCTTTNGAAATTGTATTCTTCAATGAGGCGTTTNNNATATCNNTGATTTCGTTAGTNATATTACAGTCTGANTNGGTTGTAATGTTATNCAACATATCNNNNNTGGATACGGTNCACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACNAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATANAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAANNCTNAANTAATCAANTTTTNNNNNNNGTTTTTACTACAACTAGTTTTCATCANNGTAGTGACGATGNNTTGTTTAGTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTGGTAACNTTGATAGCCGTAGATCTTTGTTCCNTCGCTAANNNGTTNANNAAATTAATAAAGAATTTGTTGTTTNNATTTATGTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGNTTATAATCTNATCATTGANNNNTACTCTGTTACCATTGTAATAAATTGGTACTCTATCNNNATCANCGACNNAGTACTGTTCATANATGATGAGATGTTTATATGTTGGCATANNNNNNNNNNNGACGTTTNGTAATGGCAANNNNNNNNNATTAACNNCATAATGTCTAGCAGCANCTGCGATGTTATAAGTGATGTCAAAGCNNGGTTNATCTTNNNNNNTTATATATTGTCTAACACCTATAANATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAANTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCNAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGNAAAAGCTGTGAGTATTAATAATANGGTTAGNTTNCGAACTAATGNNNNTTNGATGATNNNTAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACANTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACNAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCNNNAGGAAATATCATCACAACNNAATGAAGATCTNTTTCCAGNNNNNNNTTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTNGAGAGTTATTGATATCGGAACAACGTCAACAACNAGNAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTNTGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGNAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCNAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCNAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCNTTTTATTAGTGGGCATCTTTTTAGATGGTTTCNTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCNTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGNTTTTTAAGCTGTGGTGTAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTGCTTNNNCCACATAGAATAAANTAGCATTCCGACTGTGNNNATNNTACCNNGTATAAACGCCATAATACTNAATACTTNNCATGNNCGAGTNGGACTGGTAGACTTACTNNAGTCANNAAAGGCGANNATACACGNAAGAATCNNNAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTNCATTTAACTAATNAAAATTTTAAATCGCCGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTAATATCTANTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTNNNCNGCATNTTATAACTAACAGCAGCAACGGCTCGTAANNNNNTATCATTTACTAGACGAAAAGGTGGTNGGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACGTATAATGCNNNATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCNAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACANNATTTTGCCACGCTATCACTATCACCCNGGAGATAATCNTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCANNAGNATATTTTAAATNCTTAATATATTCANGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGNAAGAACTACATGGTTCTCCANGAATTAATACATATTGTTTAGCAAATTCAGGAACTATNAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTNCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTNAAAAAAATGACTTGTGGTCAGACCATAAGTCNTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATNAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTANTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATANTATTATTAATATTGCCAAGTTATCCGATCNNNAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCNGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACNATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCNAAAAAATAAAGTACATGATANGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTNGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACNNGTATTAAATAGAATATTTAANNNNCAAAATCNNNNNNAAGNTTNNNAGACGATCNNCATGCTGNGCNNGCCAGTGTATTANCCCTCATAGTATTAATATAATCCAATGATACNTTTGTGATGTNNGAAATNTTAACCAATTTAGACTGACAGGCANNACACGTCATACANNNATNATCGTCATCGATAANTNTAGTCNTGGGCTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCTGGTATANNGTCTCTATCTTTATNNCAATATAGTGTATCAACATCTTNNTTATTGACCTCNTTTATCTTNGAACATGGAATNGGNACATTTTTGTTAACNGCCACNNNTNCCNTAATTCCAGATGTTGTNAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTNTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTNAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAANNNNTTAGTCTGTACNAAAGTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGTAACTAATGTCNNGACGTCCATATCTGATTATTATGATGAGGTAAAAAANAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAANGGTAAAAATATGGTAGAACTTGGATCTGGAAACTNTTTTCAAATACCGGATNAGATTCNAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGANGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATNGTATAGGAGATAATNTTTTTATTCCTAGCGTTATAACAAAATCAGGNAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATNGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATNGACACTANNNGACGAGACTANTATGNNNNTGNNNANTANNNNNNNNNNGTTGGTATTGCAGGCNNNAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAANNNTCGATGAGTTAGTTGATGAGATTAATAAATCNNNAACTNTNAAACGAAAAANNAAAAACCAANCAGTATTTGATTTNAGNAGAGAATGNTTGGGATATCCNNNAGCNGANTTTATAACNNNAGTNNNTAACATNNNGTTCNNANNAGNAAATNNTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAANTATATANGGAAACNNCAACCANTTCGTCTCAATCTTTAATACCGTTACCGATGTCNAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCNAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGNAGGTCACCGTANNTCAAATTTATCTATTTTATTNAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTNTTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGNAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATNNNNNCATTCGGATTNCGAGANTNCGTTNCNGATAGACNNNNATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATNAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTNAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGNTTTNCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGNAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGNAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGNTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGANNNNTANATTTNCAATATGTATNNNNNNNNNNNNNNNNNNNNNNNNGATTGCANGAAATNTTGANNNNCAANCGGCCNCTCNTATCGTTTNANAATAATACAGAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACGCATTANCCACGTTCACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCNNGTTCNNNANNTCATAGGTGGAGNCTTTATCNNNNNACAATCNNNNNNAAAAGTANNNATTAATCTANTAGAAAAGATTACAACATGGCCAAAATTTANGGTTGTTNANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTCATTNGACGTAGTTTATCATACGNTATGCCTCNNNAAGTTGTCTATCTAGTAAANGCGATAATAGANANNGCTAANNNACTTANCGAATCTATTACTGACTTTNATATTGNNNNNTACATTAATGACCTGGTGNNAGCTGAACACNNNAAACNAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACNTTTTACCTCNNATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACNTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATNCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGNGTGGAAAGTTCNNAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTNCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGNAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCNAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATNNGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCNAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTNAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTNNAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGNNNACGTGGAGGAGGTATCAAGTTTGNAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCNNCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCNTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCNTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCNNATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCNTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCNATGCTTCCNNGNNATAGTCTGGAACACTAATGGGTGACGNAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGNGCGGCNGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATNNCATATCATATTNNAAAATCTTGATNGAAGNNCGAATATCTCGTCTGACNNAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTNCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGNTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGNTTTTCTACCTCAGTGGCGAAATCTTTGGNGTGTTTGGTACANTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGNTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCNTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCNAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCNTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAANAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTNAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATNAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCNAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATNGGAAATGTAATAGTAANTTTTTATCATAAAAGTTGTAAAGTAAATAANAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCNGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTNNAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTNTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGANTATTATACTCTGTATTAGTTCNGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGNAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATANNCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATNAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAANTTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCNTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTNAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCNTAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGNAGTTANTTACGTTGAACAAGTNCATGGNAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTNGAGGATGTGATTCCATAGGCAGTCNNNAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACANTTTCTTNNNATTAACGAGAATGGCGTTTNATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGANGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACNGAAATACTATATCNNNCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGANACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATNAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAANNTTTTTTATAGTATGAAGGNNNNGATGNNNNNNNNNATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATNAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTANTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTNAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATNAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTNGATAATCCATTTATNTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTANNNGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTNNNNNNAAATACNTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATANGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTNAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATANCCAATAGAATAGTATTCTCAGAGTTGACGAATANTNGTNNNGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTNNGACGATGAATNCGGTAAATGGNNGACGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCGATTTTGTAGTAGATGATNCGNAACAATCTCAGATATGGGAAATTTCAGGAGCAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNANGAAATAAATCATATNNAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTNAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCNTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCNAGACTACATTNNNGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATANNTTTTTTTAAGCACGAAATNAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTANGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCNNAAAGNAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGNGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTANTTTTTTCTGTAATAGTTANAAANNACNNNCGATGGTCTATCTACCAGATTATNNNNTGTTATAAGGTACTTTNNTCNTAATAAACTAGAGTATGAGTAAGATAGTGNTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTNAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATNAAAATGTNCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATANNTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGNAACATACGATAAAGNAAAAGATTGTTGGACATTNGATAATGGTCACTTGTTACCACATAATTATATAATGNNTAAATGCGAACCGTTTNAACATAGATATCCATTNNNNAAAANACAGTACACGAATGATTTTCNNNAGTATTTNNNAAGNTTTATANNNAGTTNATAGAACAAAATACATNANTTTGTNAAAATAAATCACNTTTTATACTAATATGNNACAATTANCAATACTTTTGTTACTANNNNCNNTAGTATACGCTACACCTNNTCCTCNGANATCTNAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATNAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTNNANNCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCNAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTNNNTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTNTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACNATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGNTTTATACAAATCCATTAATGTNGAATATCGATTCTTNGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAANAATAATAGACTACCAGNAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGNAATATAGTCTTGGATCAAATAGATAAGAATAAANTATATCTAGTGGATTACGGATTGGTTTCTAAANTCATGTCTAACGGCGAACATGNTCCNNNNATAAGAAANCCAAATNAAATNGATNNNNGTACTCNAGAATTTACACCTATAGATTCGCATNAANNATACNNNNNNNNNAGACGTGGTGATCTAGAAACANNNNGATATTGTANGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAATTGCNNNAATATATTANNATGGTANNNNNNNNNACATATTTTGAGGAACCNAATTACGACNANNTTNNNNNNNTNTTNNNNNNNNGANNTNNNNNAAATTTTTNTNGATNNAANNNNNNNAAAAATAACTNNGTTATTATCANNCTCGTGAGNANAATNGAAACANNNNGNNGNNNNACGNNCACGCTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCATCGACNGTTGCCNNNNNNGTCANGAAATATTCTGTTGTGTCAGTTTATAATNAAAAGTATAACATTGTAAAAAACAAANATATGTGGTGTAACAGTCAAGNGAACAAGAGATATATTNGAGNNNNNNNNNNNNNGTNTGAATGCAATGAATATCTACAAATTGGAGATNCAATCCATGATCTAGAAGGAAATCAAATNTNTATTGTCACATATCGCCACAAAAACNACNATGNTCNAAGTGGAANNNNNNACGAGAGTCTAGANNTGTGNTTGGAANGAGTANGGATNNNTCATCACGTACTTGAAACAGGAANNNNGGTATATGGAAAAGTNCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGNGNCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCNNTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGNGAAAGACACTGAATCAATNGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATNGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGANTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACNTTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATNNAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGNTTTTTGTATCAAAGACATTAATACTTTAATGAGATACNGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATNCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAATACTTNNNNGAATGATANNNTCNCGTGTCCTANNNNNNNNNNNNNNNNNNNNCNNTTAGAACACNGATCNTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCCAACANNTGTACGATCTAACGAAGAATTTGATCCAGTNGATGATGGTNCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATNAGCTAGAATCAATTAGATGTCTTCTTCAGTNGATGTTGATATCTACGATGCCGTTAGAGCANTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTNGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACANTTAATGGTATAATGATGAATGAATTCGATACNGTATGNGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTNTAGCTAATNNGAGATATNGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATNAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGNTGCATCCTATTCGAATAATGAGTACANNCCGTTTAATAAACTGAGTGTNAAACTCNATATNGANNGAGTAGATAATATAGNAAATNNNNATACTGATGATAATAATNAANNNGTGTTANNNNNTNAANAGTNNACNNTTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCANAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCNAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACNTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCNATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGANNNAACATNGGGNTTAAAAATANGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACNGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACNCAACAAACACGTCTTGGATCATCNCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCNAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCNGGAGACATAAAATTTGAGGAGNATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTTAACAATTNGTTCTGATCTACAGACANNNNTTAATAAATCANCTTATTTTNCCAANATATTAAAANNNNNNNACNNCACNNNTNNNNNNNNATTGTGCGNCTTTCAAGATGATGNNNNATATAGGGTNNTACAGTTTTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAAATTATTTGNNTAGAATATTACGNNTATAATTGTTTNGAAATTTATAGAATAACNNNTATTAATACATTATNGTATATCTACAACGNTATNAGNNNCTTCATATTNGATAATATTACTANTAATATNNNNGGATNCAGANTTNNNNNNNTTGCCTAAATACATNNTTATAGNNTTACNNNGACAATCACCTAAATGTTTTNNACGNAGATAANNNGGTAAAGATTATNNNNACTTNTANNNCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATANNTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATNGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATANAGATGTAGAAGATATCATGAATGAAATAGATAGAGANAAAGAAGAAATACTNAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTANAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCNCGATGTAGGAATATAGANCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGNTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATNGATCATAAATCACNCAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCNTTGACTATCAACAACTGGACACGAGAANNTGGTATAAANNATTTGGCTATTNCAGATCTGNNTNNAATTGGAGAAACCGATGATTATATGTTCNTCATTATAANNAATTTGGGAAGAGNANTCGCCCCAAAGGATNGTGAATCAGNNTTCGAAGCATGTGTCACTATGATNAACACGTTNGAGTTTATACACTCTCAAGGATTTACTCATGGNAAAATNGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGANGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTNCATGGNNAAACGAAAGTAGTATNNAAGTAATAAAACNNAAAAAAGAATATAAACAATTTATAGCTACNTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAANTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATNNTANNCNNNTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCNAATATTAATATTAGACTATCTCTANCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCANCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATNNCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNNNCTTTAAAGCNNAATNGTTGATGCCATTCGAAANNGAATTTACCAGTGATTATCCCNNNNACGTATCTCCNNNNNAAATNGTAGNNGNNNGNATNATGTCTATTTNCGGCGAGCCANTTAATCACGCATCTNNNNNNNAATCATTCNGNAACNNNNCAATCATAGAACTGCCATATGTTGGNGATNCTAGTATGATGGNCATTCTTCCNAACAAGATTGATGGATTAGAATCCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATAATCTTGTNNATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGNGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGANGNGTATACAGAAGCAGCTGCAGCAACTTCNGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCNTTTCGTTGGTAGATATTGCTNTNCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACANNTTTTTTTAAAAATAGNAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTNGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTNGATNTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGNNNNNNNNANNNNNNNNNNNNNNNNTTTAAAGATGATGNGGAATCAGTNNNNATCGACGTNCGTGAGCTGGNNAAAAATATGCCGTGGGATAATGTTNAGGATTGTACAGAGATCATCCGTTGTTATANANNGGATGAGCNAAAANNNATCNNNNAGATTTCGGCCATCATTGGANTTTNTNNATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACNTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATANTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGANNATATATATATATATATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACNTCAATAGGTNGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTNGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACNNTATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGANCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGNTCTCNGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATNGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTNTACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTNAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATNAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTTTAGATANCNNTAGATCACTTGATGGGTANGATATTAATTGTTACTTNNNNNGACGTACACCACTTCATTGCGCTATACAATATNNNNNNACNCAGATTGCTGANTACTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTGATTAGTCGTCTACCGCCTAAAAGNGTNATATGCTCACTGACTAACCATATAATAGATTATGTTCNTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTANNAAGTACGTACTGTTACTGGACCCATCNNNNTATTATAGANTCAGNAATGTTATCGNNNACAAATTAGACCAATACAATAATCGTTATAATATNTTCGAACACGATANNGACGTTAANNNNNNNTATGGCAAAGTCNTACATGANCTNGATACATATATCNAGGNNGTNNAAGTATTAAAATCTACTTCCATCNNNAATAATATAACACTATACGACACNNNTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAANCTNATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTANAGAAATATACTTTAACTNATATAGTCCTNNAGNATATGATCTCATCTCNNTCTCAATCATCTTATTTGAGTCGTATTNCTAATGAGANNNTACTCGAAATATTATATAAANTCGACATGTACGATTTANNNNNNNNNNNNNNNNNNNATATNNGAGAGAATGATATCACAGAGTATCATATNNAGAATACGANGTCTGTTTCTNNANNGACATGAATAATGANNACACATNNAACNNNNTTTTTAATCTTNGATATAACACTAATTACATCNAGATTATATATTNAAATCGTAATTTGAGTTGTCTGATCNNCATGNNNNNNNNAAANNATATACNNAACATNNGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATATAGAGAATATGAATGAGAATACANCCGATGATNAGNAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACNAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGNAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTANAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTNAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCNAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCNAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATNGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGNAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGNTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATNCATAAAAATGACACTGTTGACAATAACACNATGGTTGATNANGNGACANCTAACAATAACACATTACATGGTAATATAGGANTTTTNGAAANAAATAATTGTTATANNNTTTCNGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACANGAACNAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTNATGGCATCCGTTATTCCTGCAGTTAANGAANTTAACAATACGTTGATGAAAATTGGTGTNAAAGATNATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTNTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTANNNACAATAGTGTTTCGACNNCTAACAGCAGNAAAAGACGAGATCTGAATGATGAGTTTGAATTTTNCACTTNCNAGGAATTAGATTGTCTTTACGAATCNTATGGTGTAAANNATGATATAAGTCATTGTTTTGCATCACCTAGACNNNGACGATCNGACGACNAAANNNNGTACATGGACNNGNAATTATTCNACNNCGNNNANNNNNANTTNGGAATAGACAGTGTTATTNCTNGANGTACAACCCATTTNCAAGTANGTGCATCTGGTGCNNNTGGTGGTGTTGNAGGAGATAGNTTNNCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGNAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCNAAAGCTTTCTAATGTTNGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCNAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTNCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTNAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATNAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTNAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCNGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATNTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTNACAAAATCCATTTAGACAAGAAGGGACATATAAGCNACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAANCTATGATATTGGAAGATGTATNATNGTGTAGTTCTAGAACTAGNAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTNTTACAGCAACCTCCTTNNACATTCGAATTCATTCNTGACAATTCTAACGAATATGTGGATANAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGNCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACNAAGATATAAAAGACATTATAGAATCCGAAGAANGTAAGAGATNNNNTATAATAGATGTTANNAACAATCTTGTTNNAAAGTACTATTNTATTGATAATTATCNNTGTNATACTTTAGATGATTATATATACANCTCTGNAGAATATAACAANNNCTNTNTGTTAGNAAACGATACTTNTATANGCNNNNACTATCNTGAATCATCAGNNGTANNNGTTNTATCATNTTATGAAANGACTANAATCTCCTTNGATACNAAAGACGCCAAAGATGCTATAGAAGATGTGANNNTAGCNAGTGCNGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATNAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGANNTTTTTTAAATGAGTATCGGTAGTTACANNNTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTANCNNGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGNTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGNNCACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGNGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAANGGTACTTATNCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTNATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCNNGATTTTCGCATTGACTTTACACAGACATGAACATNCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAANGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTNCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCNAAAACTCACTTTTGANTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATNAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATNNAANTGATATAACNAATACAGCAGATATATTGCTNGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGNAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATNAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGNNAGTTAAGTNNTNNGTTAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGNNNNAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATNAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGNACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTNGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATNTTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTNCATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCNGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAANNAAAGTGTGGAATAGGATACGGAGTATCCGGNTACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTNCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTANNAACTTCAGGATTCTTTACNGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTNGNNNNNNNNNNNNNNAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTNTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATNCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGNNAGNTNCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGANNTATCCGAAGAAGTTGTNAAAGGAGATCCCACCACTTATTACACTATCGTCNGTGCGGGTCTTNNNATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACANTGTGAATACTAGATTGTCCAGCGTGTCACCNGGACAAGGTAAGGANNCTNCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATNCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGNTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGNNCGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCNNCGGATCGGCATCTGAAGGTGCAACCGATGATACTTNACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGNAAATGGATGAGTTNGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACNAAAATATTTAACTACATTCACAAAAAGTTANNNCTCGTTACTTCTTCNTTCTGTTTCAATATGTGATACGATATGATCACTATTCNTNTTCTCTTGGTCTCATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +>Monkeypox/PT0008/2022|sampling_date_20220515 +TAATTAATTTAATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTTGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTANTAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTTGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGAGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTNNANNNNNNNNNNNNNNNNNNGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGAGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTAAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAAAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATTAAATTAATTA +>MPXV-UK_P2 | MT903344.1 +TAATTAATTTAATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAANNNNNNNNNNTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATTAAATTAATTA +>KJ642617 +CGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATGATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATCGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCATACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAGATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTCGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTCGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACGCATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCGTCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAAGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACCGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCCAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACGAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGCATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGATGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATATATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGATGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGCGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGTCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACCCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAGATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGGCTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTCTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTACGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCRTCATCATSATCATCATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCGTTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACGAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGCGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACCGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGTCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCATGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAAATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCTATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCATGTAGGTCTTATCACGTGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAAGATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGGAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAGAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATCATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCG +>ON676708 +ATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATTATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGTTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTTTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGNNNNATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATNNNAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAAT +>ON674051 +TATTATATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATANTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTATAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATTAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTTGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATTAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATTACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTTCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACAAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATAAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTTATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAAACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTTGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTTAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTAATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTAAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAAAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGAACGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAAATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATTTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATAGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAAACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCNNNTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGCGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATTATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTTTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCAAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTTAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACAATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTTATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAATGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATTACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGAAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTTCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACACCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGANNATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTTGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTTATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAANTATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATATAATA +>MT903339 +CGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCAAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTTGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCAATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACAAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCG +>ON843165 +TAATTAATTTAATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTTTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTTGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGAGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGAGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGNNNNNNNNGCNNNNNNNNNNNNNTTTCACGACGACCTCGATCNNNNNNNNNTNNCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATTAAATTAATTA diff --git a/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/tree.json b/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/tree.json new file mode 100644 index 00000000..b8d70c14 --- /dev/null +++ b/data_output/nextstrain/mpox/lineage-b.1/rivers-with-usa-2022-ma001-snps/unreleased/tree.json @@ -0,0 +1 @@ +{"version":"v2","meta":{"title":"Nextclade reference tree for hMPXV-1 clade B.1 (reference seq: ON622721.3 in NC_063383.1 coordinates)","updated":"2023-11-16","build_url":"https://github.com/nextstrain/monkeypox","data_provenance":[{"name":"GenBank","url":"https://www.ncbi.nlm.nih.gov/genbank/"}],"maintainers":[{"name":"Nextstrain team","url":"http://nextstrain.org"}],"display_defaults":{"color_by":"lineage","map_triplicate":false,"distance_measure":"div","transmission_lines":false,"tip_label":"strain_display"},"genome_annotations":{"OPG001":{"end":1575,"seqid":"resources/genome_annotation.gff3","start":835,"strand":"-","type":"gene"},"OPG001_dup":{"end":196375,"seqid":"resources/genome_annotation.gff3","start":195635,"strand":"+","type":"gene"},"OPG002":{"end":2751,"seqid":"resources/genome_annotation.gff3","start":1702,"strand":"-","type":"gene"},"OPG002_dup":{"end":195508,"seqid":"resources/genome_annotation.gff3","start":194459,"strand":"+","type":"gene"},"OPG003":{"end":4607,"seqid":"resources/genome_annotation.gff3","start":2841,"strand":"-","type":"gene"},"OPG003_dup":{"end":194369,"seqid":"resources/genome_annotation.gff3","start":192603,"strand":"+","type":"gene"},"OPG005":{"end":189660,"seqid":"resources/genome_annotation.gff3","start":189199,"strand":"+","type":"gene"},"OPG015":{"end":6156,"seqid":"resources/genome_annotation.gff3","start":4843,"strand":"-","type":"gene"},"OPG015_dup":{"end":192367,"seqid":"resources/genome_annotation.gff3","start":191054,"strand":"+","type":"gene"},"OPG016":{"end":190940,"seqid":"resources/genome_annotation.gff3","start":190410,"strand":"+","type":"gene"},"OPG019":{"end":8008,"seqid":"resources/genome_annotation.gff3","start":7580,"strand":"+","type":"gene"},"OPG021":{"end":10315,"seqid":"resources/genome_annotation.gff3","start":9587,"strand":"+","type":"gene"},"OPG022":{"end":10858,"seqid":"resources/genome_annotation.gff3","start":10478,"strand":"-","type":"gene"},"OPG023":{"end":12900,"seqid":"resources/genome_annotation.gff3","start":10918,"strand":"-","type":"gene"},"OPG024":{"end":13228,"seqid":"resources/genome_annotation.gff3","start":13034,"strand":"-","type":"gene"},"OPG025":{"end":15267,"seqid":"resources/genome_annotation.gff3","start":13375,"strand":"-","type":"gene"},"OPG027":{"end":16377,"seqid":"resources/genome_annotation.gff3","start":15925,"strand":"-","type":"gene"},"OPG029":{"end":17069,"seqid":"resources/genome_annotation.gff3","start":16602,"strand":"-","type":"gene"},"OPG030":{"end":17833,"seqid":"resources/genome_annotation.gff3","start":17213,"strand":"-","type":"gene"},"OPG031":{"end":18828,"seqid":"resources/genome_annotation.gff3","start":17878,"strand":"-","type":"gene"},"OPG034":{"end":20005,"seqid":"resources/genome_annotation.gff3","start":19361,"strand":"-","type":"gene"},"OPG035":{"end":20404,"seqid":"resources/genome_annotation.gff3","start":20051,"strand":"-","type":"gene"},"OPG036":{"end":21064,"seqid":"resources/genome_annotation.gff3","start":20531,"strand":"-","type":"gene"},"OPG037":{"end":22433,"seqid":"resources/genome_annotation.gff3","start":21105,"strand":"-","type":"gene"},"OPG038":{"end":23159,"seqid":"resources/genome_annotation.gff3","start":22497,"strand":"-","type":"gene"},"OPG039":{"end":24118,"seqid":"resources/genome_annotation.gff3","start":23264,"strand":"-","type":"gene"},"OPG040":{"end":25478,"seqid":"resources/genome_annotation.gff3","start":24351,"strand":"-","type":"gene"},"OPG042":{"end":27097,"seqid":"resources/genome_annotation.gff3","start":25823,"strand":"-","type":"gene"},"OPG043":{"end":27955,"seqid":"resources/genome_annotation.gff3","start":27125,"strand":"-","type":"gene"},"OPG044":{"end":28540,"seqid":"resources/genome_annotation.gff3","start":28091,"strand":"+","type":"gene"},"OPG045":{"end":29262,"seqid":"resources/genome_annotation.gff3","start":28603,"strand":"-","type":"gene"},"OPG046":{"end":29729,"seqid":"resources/genome_annotation.gff3","start":29274,"strand":"-","type":"gene"},"OPG047":{"end":31194,"seqid":"resources/genome_annotation.gff3","start":29746,"strand":"-","type":"gene"},"OPG048":{"end":32164,"seqid":"resources/genome_annotation.gff3","start":31205,"strand":"-","type":"gene"},"OPG049":{"end":33151,"seqid":"resources/genome_annotation.gff3","start":32195,"strand":"-","type":"gene"},"OPG050":{"end":33408,"seqid":"resources/genome_annotation.gff3","start":33181,"strand":"-","type":"gene"},"OPG051":{"end":33649,"seqid":"resources/genome_annotation.gff3","start":33425,"strand":"-","type":"gene"},"OPG052":{"end":33995,"seqid":"resources/genome_annotation.gff3","start":33801,"strand":"-","type":"gene"},"OPG053":{"end":34690,"seqid":"resources/genome_annotation.gff3","start":34052,"strand":"-","type":"gene"},"OPG054":{"end":35996,"seqid":"resources/genome_annotation.gff3","start":34677,"strand":"-","type":"gene"},"OPG055":{"end":37083,"seqid":"resources/genome_annotation.gff3","start":36019,"strand":"-","type":"gene"},"OPG056":{"end":39034,"seqid":"resources/genome_annotation.gff3","start":37127,"strand":"-","type":"gene"},"OPG057":{"end":40195,"seqid":"resources/genome_annotation.gff3","start":39077,"strand":"-","type":"gene"},"OPG058":{"end":40434,"seqid":"resources/genome_annotation.gff3","start":40213,"strand":"-","type":"gene"},"OPG059":{"end":40633,"seqid":"resources/genome_annotation.gff3","start":40484,"strand":"-","type":"gene"},"OPG060":{"end":41182,"seqid":"resources/genome_annotation.gff3","start":40706,"strand":"-","type":"gene"},"OPG061":{"end":41884,"seqid":"resources/genome_annotation.gff3","start":41189,"strand":"-","type":"gene"},"OPG062":{"end":42252,"seqid":"resources/genome_annotation.gff3","start":41947,"strand":"+","type":"gene"},"OPG063":{"end":43688,"seqid":"resources/genome_annotation.gff3","start":42249,"strand":"-","type":"gene"},"OPG064":{"end":45898,"seqid":"resources/genome_annotation.gff3","start":43685,"strand":"-","type":"gene"},"OPG065":{"end":46483,"seqid":"resources/genome_annotation.gff3","start":46022,"strand":"-","type":"gene"},"OPG066":{"end":47428,"seqid":"resources/genome_annotation.gff3","start":46649,"strand":"-","type":"gene"},"OPG068":{"end":49904,"seqid":"resources/genome_annotation.gff3","start":48201,"strand":"+","type":"gene"},"OPG069":{"end":50486,"seqid":"resources/genome_annotation.gff3","start":49986,"strand":"+","type":"gene"},"OPG070":{"end":51411,"seqid":"resources/genome_annotation.gff3","start":50590,"strand":"+","type":"gene"},"OPG071":{"end":54438,"seqid":"resources/genome_annotation.gff3","start":51418,"strand":"-","type":"gene"},"OPG072":{"end":54757,"seqid":"resources/genome_annotation.gff3","start":54470,"strand":"+","type":"gene"},"OPG073":{"end":55141,"seqid":"resources/genome_annotation.gff3","start":54752,"strand":"-","type":"gene"},"OPG074":{"end":57125,"seqid":"resources/genome_annotation.gff3","start":55128,"strand":"-","type":"gene"},"OPG075":{"end":57498,"seqid":"resources/genome_annotation.gff3","start":57172,"strand":"-","type":"gene"},"OPG076":{"end":57630,"seqid":"resources/genome_annotation.gff3","start":57523,"strand":"-","type":"gene"},"OPG077":{"end":58583,"seqid":"resources/genome_annotation.gff3","start":57645,"strand":"-","type":"gene"},"OPG078":{"end":58811,"seqid":"resources/genome_annotation.gff3","start":58590,"strand":"-","type":"gene"},"OPG079":{"end":59621,"seqid":"resources/genome_annotation.gff3","start":58812,"strand":"-","type":"gene"},"OPG080":{"end":62018,"seqid":"resources/genome_annotation.gff3","start":59703,"strand":"-","type":"gene"},"OPG081":{"end":62285,"seqid":"resources/genome_annotation.gff3","start":62046,"strand":"-","type":"gene"},"OPG082":{"end":63452,"seqid":"resources/genome_annotation.gff3","start":62304,"strand":"-","type":"gene"},"OPG083":{"end":64716,"seqid":"resources/genome_annotation.gff3","start":63445,"strand":"-","type":"gene"},"OPG084":{"end":66752,"seqid":"resources/genome_annotation.gff3","start":64722,"strand":"+","type":"gene"},"OPG085":{"end":68531,"seqid":"resources/genome_annotation.gff3","start":66756,"strand":"-","type":"gene"},"OPG086":{"end":68863,"seqid":"resources/genome_annotation.gff3","start":68528,"strand":"-","type":"gene"},"OPG087":{"end":69519,"seqid":"resources/genome_annotation.gff3","start":68857,"strand":"+","type":"gene"},"OPG088":{"end":69863,"seqid":"resources/genome_annotation.gff3","start":69489,"strand":"-","type":"gene"},"OPG089":{"end":71170,"seqid":"resources/genome_annotation.gff3","start":69866,"strand":"+","type":"gene"},"OPG090":{"end":71370,"seqid":"resources/genome_annotation.gff3","start":71179,"strand":"+","type":"gene"},"OPG091":{"end":71867,"seqid":"resources/genome_annotation.gff3","start":71370,"strand":"+","type":"gene"},"OPG092":{"end":72947,"seqid":"resources/genome_annotation.gff3","start":71832,"strand":"-","type":"gene"},"OPG093":{"end":73760,"seqid":"resources/genome_annotation.gff3","start":72978,"strand":"+","type":"gene"},"OPG094":{"end":74802,"seqid":"resources/genome_annotation.gff3","start":73780,"strand":"+","type":"gene"},"OPG095":{"end":75555,"seqid":"resources/genome_annotation.gff3","start":74803,"strand":"+","type":"gene"},"OPG096":{"end":75865,"seqid":"resources/genome_annotation.gff3","start":75587,"strand":"+","type":"gene"},"OPG097":{"end":76875,"seqid":"resources/genome_annotation.gff3","start":75841,"strand":"-","type":"gene"},"OPG098":{"end":77655,"seqid":"resources/genome_annotation.gff3","start":76900,"strand":"+","type":"gene"},"OPG099":{"end":78051,"seqid":"resources/genome_annotation.gff3","start":77665,"strand":"+","type":"gene"},"OPG100":{"end":78466,"seqid":"resources/genome_annotation.gff3","start":78008,"strand":"+","type":"gene"},"OPG101":{"end":79019,"seqid":"resources/genome_annotation.gff3","start":78486,"strand":"+","type":"gene"},"OPG102":{"end":80086,"seqid":"resources/genome_annotation.gff3","start":79085,"strand":"+","type":"gene"},"OPG103":{"end":80558,"seqid":"resources/genome_annotation.gff3","start":80001,"strand":"+","type":"gene"},"OPG104":{"end":81019,"seqid":"resources/genome_annotation.gff3","start":80618,"strand":"-","type":"gene"},"OPG105":{"end":84986,"seqid":"resources/genome_annotation.gff3","start":81126,"strand":"+","type":"gene"},"OPG106":{"end":85498,"seqid":"resources/genome_annotation.gff3","start":84983,"strand":"-","type":"gene"},"OPG107":{"end":86081,"seqid":"resources/genome_annotation.gff3","start":85512,"strand":"+","type":"gene"},"OPG108":{"end":87059,"seqid":"resources/genome_annotation.gff3","start":86085,"strand":"-","type":"gene"},"OPG109":{"end":89447,"seqid":"resources/genome_annotation.gff3","start":87060,"strand":"-","type":"gene"},"OPG110":{"end":90264,"seqid":"resources/genome_annotation.gff3","start":89632,"strand":"+","type":"gene"},"OPG111":{"end":91209,"seqid":"resources/genome_annotation.gff3","start":90265,"strand":"+","type":"gene"},"OPG112":{"end":91687,"seqid":"resources/genome_annotation.gff3","start":91247,"strand":"+","type":"gene"},"OPG113":{"end":94268,"seqid":"resources/genome_annotation.gff3","start":91731,"strand":"+","type":"gene"},"OPG114":{"end":94667,"seqid":"resources/genome_annotation.gff3","start":94227,"strand":"-","type":"gene"},"OPG115":{"end":95361,"seqid":"resources/genome_annotation.gff3","start":94660,"strand":"+","type":"gene"},"OPG116":{"end":96017,"seqid":"resources/genome_annotation.gff3","start":95361,"strand":"+","type":"gene"},"OPG117":{"end":98406,"seqid":"resources/genome_annotation.gff3","start":96049,"strand":"+","type":"gene"},"OPG118":{"end":100359,"seqid":"resources/genome_annotation.gff3","start":98446,"strand":"+","type":"gene"},"OPG119":{"end":100871,"seqid":"resources/genome_annotation.gff3","start":100386,"strand":"+","type":"gene"},"OPG120":{"end":101748,"seqid":"resources/genome_annotation.gff3","start":100834,"strand":"-","type":"gene"},"OPG121":{"end":102431,"seqid":"resources/genome_annotation.gff3","start":101790,"strand":"+","type":"gene"},"OPG122":{"end":103174,"seqid":"resources/genome_annotation.gff3","start":102428,"strand":"+","type":"gene"},"OPG123":{"end":105070,"seqid":"resources/genome_annotation.gff3","start":103175,"strand":"-","type":"gene"},"OPG124":{"end":105968,"seqid":"resources/genome_annotation.gff3","start":105105,"strand":"-","type":"gene"},"OPG125":{"end":107654,"seqid":"resources/genome_annotation.gff3","start":105999,"strand":"-","type":"gene"},"OPG126":{"end":108130,"seqid":"resources/genome_annotation.gff3","start":107678,"strand":"-","type":"gene"},"OPG127":{"end":108825,"seqid":"resources/genome_annotation.gff3","start":108151,"strand":"-","type":"gene"},"OPG128":{"end":109055,"seqid":"resources/genome_annotation.gff3","start":108822,"strand":"-","type":"gene"},"OPG129":{"end":111004,"seqid":"resources/genome_annotation.gff3","start":109070,"strand":"-","type":"gene"},"OPG130":{"end":111902,"seqid":"resources/genome_annotation.gff3","start":111057,"strand":"-","type":"gene"},"OPG131":{"end":112425,"seqid":"resources/genome_annotation.gff3","start":111940,"strand":"+","type":"gene"},"OPG132":{"end":113540,"seqid":"resources/genome_annotation.gff3","start":112422,"strand":"-","type":"gene"},"OPG133":{"end":115696,"seqid":"resources/genome_annotation.gff3","start":113564,"strand":"-","type":"gene"},"OPG134":{"end":116628,"seqid":"resources/genome_annotation.gff3","start":115750,"strand":"+","type":"gene"},"OPG135":{"end":116911,"seqid":"resources/genome_annotation.gff3","start":116609,"strand":"-","type":"gene"},"OPG136":{"end":119587,"seqid":"resources/genome_annotation.gff3","start":116912,"strand":"-","type":"gene"},"OPG137":{"end":120558,"seqid":"resources/genome_annotation.gff3","start":119602,"strand":"+","type":"gene"},"OPG138":{"end":121132,"seqid":"resources/genome_annotation.gff3","start":120560,"strand":"-","type":"gene"},"OPG139":{"end":121368,"seqid":"resources/genome_annotation.gff3","start":121156,"strand":"-","type":"gene"},"OPG140":{"end":121746,"seqid":"resources/genome_annotation.gff3","start":121474,"strand":"-","type":"gene"},"OPG141":{"end":121924,"seqid":"resources/genome_annotation.gff3","start":121763,"strand":"-","type":"gene"},"OPG142":{"end":122198,"seqid":"resources/genome_annotation.gff3","start":121914,"strand":"-","type":"gene"},"OPG143":{"end":123315,"seqid":"resources/genome_annotation.gff3","start":122182,"strand":"-","type":"gene"},"OPG144":{"end":123932,"seqid":"resources/genome_annotation.gff3","start":123318,"strand":"-","type":"gene"},"OPG145":{"end":125425,"seqid":"resources/genome_annotation.gff3","start":123947,"strand":"+","type":"gene"},"OPG146":{"end":125639,"seqid":"resources/genome_annotation.gff3","start":125406,"strand":"-","type":"gene"},"OPG147":{"end":125987,"seqid":"resources/genome_annotation.gff3","start":125640,"strand":"-","type":"gene"},"OPG148":{"end":127266,"seqid":"resources/genome_annotation.gff3","start":125986,"strand":"+","type":"gene"},"OPG149":{"end":127759,"seqid":"resources/genome_annotation.gff3","start":127196,"strand":"+","type":"gene"},"OPG150":{"end":128927,"seqid":"resources/genome_annotation.gff3","start":127779,"strand":"+","type":"gene"},"OPG151":{"end":132418,"seqid":"resources/genome_annotation.gff3","start":128924,"strand":"+","type":"gene"},"OPG153":{"end":137667,"seqid":"resources/genome_annotation.gff3","start":136138,"strand":"-","type":"gene"},"OPG154":{"end":138050,"seqid":"resources/genome_annotation.gff3","start":137718,"strand":"-","type":"gene"},"OPG155":{"end":138491,"seqid":"resources/genome_annotation.gff3","start":138051,"strand":"-","type":"gene"},"OPG156":{"end":139409,"seqid":"resources/genome_annotation.gff3","start":138492,"strand":"-","type":"gene"},"OPG157":{"end":139608,"seqid":"resources/genome_annotation.gff3","start":139372,"strand":"-","type":"gene"},"OPG158":{"end":139769,"seqid":"resources/genome_annotation.gff3","start":139641,"strand":"-","type":"gene"},"OPG159":{"end":140205,"seqid":"resources/genome_annotation.gff3","start":139768,"strand":"+","type":"gene"},"OPG160":{"end":141074,"seqid":"resources/genome_annotation.gff3","start":140172,"strand":"-","type":"gene"},"OPG161":{"end":141647,"seqid":"resources/genome_annotation.gff3","start":141102,"strand":"+","type":"gene"},"OPG162":{"end":142158,"seqid":"resources/genome_annotation.gff3","start":141652,"strand":"+","type":"gene"},"OPG163":{"end":142732,"seqid":"resources/genome_annotation.gff3","start":142202,"strand":"+","type":"gene"},"OPG164":{"end":143464,"seqid":"resources/genome_annotation.gff3","start":142778,"strand":"+","type":"gene"},"OPG165":{"end":144322,"seqid":"resources/genome_annotation.gff3","start":143516,"strand":"+","type":"gene"},"OPG166":{"end":144577,"seqid":"resources/genome_annotation.gff3","start":144398,"strand":"+","type":"gene"},"OPG167":{"end":145407,"seqid":"resources/genome_annotation.gff3","start":144574,"strand":"-","type":"gene"},"OPG170":{"end":146778,"seqid":"resources/genome_annotation.gff3","start":146113,"strand":"-","type":"gene"},"OPG171":{"end":147389,"seqid":"resources/genome_annotation.gff3","start":146988,"strand":"+","type":"gene"},"OPG172":{"end":148017,"seqid":"resources/genome_annotation.gff3","start":147427,"strand":"+","type":"gene"},"OPG173":{"end":148261,"seqid":"resources/genome_annotation.gff3","start":148037,"strand":"+","type":"gene"},"OPG174":{"end":149395,"seqid":"resources/genome_annotation.gff3","start":148355,"strand":"-","type":"gene"},"OPG175":{"end":149819,"seqid":"resources/genome_annotation.gff3","start":149442,"strand":"+","type":"gene"},"OPG176":{"end":150531,"seqid":"resources/genome_annotation.gff3","start":149809,"strand":"+","type":"gene"},"OPG178":{"end":152123,"seqid":"resources/genome_annotation.gff3","start":151509,"strand":"+","type":"gene"},"OPG180":{"end":154371,"seqid":"resources/genome_annotation.gff3","start":152692,"strand":"+","type":"gene"},"OPG181":{"end":155416,"seqid":"resources/genome_annotation.gff3","start":154412,"strand":"+","type":"gene"},"OPG185":{"end":159858,"seqid":"resources/genome_annotation.gff3","start":158917,"strand":"+","type":"gene"},"OPG187":{"end":161533,"seqid":"resources/genome_annotation.gff3","start":160622,"strand":"+","type":"gene"},"OPG188":{"end":163107,"seqid":"resources/genome_annotation.gff3","start":161596,"strand":"+","type":"gene"},"OPG189":{"end":165018,"seqid":"resources/genome_annotation.gff3","start":163333,"strand":"+","type":"gene"},"OPG190":{"end":166075,"seqid":"resources/genome_annotation.gff3","start":165122,"strand":"+","type":"gene"},"OPG191":{"end":166667,"seqid":"resources/genome_annotation.gff3","start":166161,"strand":"+","type":"gene"},"OPG192":{"end":167279,"seqid":"resources/genome_annotation.gff3","start":166731,"strand":"+","type":"gene"},"OPG193":{"end":168137,"seqid":"resources/genome_annotation.gff3","start":167334,"strand":"+","type":"gene"},"OPG195":{"end":168895,"seqid":"resources/genome_annotation.gff3","start":168230,"strand":"+","type":"gene"},"OPG197":{"end":169972,"seqid":"resources/genome_annotation.gff3","start":169670,"strand":"+","type":"gene"},"OPG198":{"end":170886,"seqid":"resources/genome_annotation.gff3","start":170038,"strand":"+","type":"gene"},"OPG199":{"end":172022,"seqid":"resources/genome_annotation.gff3","start":170988,"strand":"+","type":"gene"},"OPG200":{"end":172599,"seqid":"resources/genome_annotation.gff3","start":172150,"strand":"+","type":"gene"},"OPG204":{"end":175587,"seqid":"resources/genome_annotation.gff3","start":174532,"strand":"+","type":"gene"},"OPG205":{"end":178019,"seqid":"resources/genome_annotation.gff3","start":175656,"strand":"+","type":"gene"},"OPG208":{"end":180339,"seqid":"resources/genome_annotation.gff3","start":179266,"strand":"+","type":"gene"},"OPG209":{"end":181090,"seqid":"resources/genome_annotation.gff3","start":180518,"strand":"+","type":"gene"},"OPG210":{"end":186998,"seqid":"resources/genome_annotation.gff3","start":181356,"strand":"+","type":"gene"},"nuc":{"end":197209,"start":1,"strand":"+","type":"source"}},"colorings":[{"key":"clade_membership","title":"Clade","type":"categorical","scale":[["IIb","#DEA73C"]]},{"key":"gt","title":"Genotype","type":"categorical"},{"key":"outbreak","title":"Outbreak","type":"categorical","scale":[["hMPXV-1","#4C90C0"]]},{"key":"lineage","title":"Lineage","type":"categorical","scale":[["B.1","#4041C7"],["B.1.1","#3F53CD"],["B.1.2","#4064CF"],["B.1.3","#4375CD"],["C.1","#4784C8"],["B.1.4","#4C91BF"],["B.1.5","#539CB4"],["B.1.6","#5AA5A7"],["B.1.7","#63AC9A"],["B.1.8","#6CB28C"],["B.1.9","#77B67E"],["B.1.10","#82BA71"],["B.1.11","#8FBC66"],["B.1.12","#9CBE5B"],["B.1.13","#A9BD53"],["B.1.14","#B5BD4C"],["B.1.15","#C1BA46"],["B.1.16","#CDB642"],["B.1.17","#D6B03F"],["B.1.18","#DEA73B"],["B.1.19","#E39B39"],["B.1.20","#E68D36"]]},{"key":"date","title":"Collection Date","type":"categorical"},{"key":"host","title":"Host","type":"categorical"},{"key":"strain_display","title":"Pretty strain name","type":"categorical"},{"key":"strain","title":"Strain name","type":"categorical"},{"key":"region","title":"Region","type":"categorical","scale":[["Asia","#447CCD"],["Oceania","#5EA9A1"],["Africa","#8ABB6A"],["Europe","#BEBB48"],["South America","#E29E39"],["North America","#E2562B"]]},{"key":"country","title":"Country","type":"categorical","scale":[["Israel","#5E1D9D"],["Taiwan","#4D23AE"],["South Korea","#4432BD"],["Japan","#3F43C7"],["Australia","#3F56CE"],["South Africa","#4067CF"],["Portugal","#4379CD"],["Ireland","#4887C6"],["Spain","#4E95BD"],["United Kingdom","#559FB0"],["France","#5DA8A3"],["Belgium","#67AE94"],["Netherlands","#71B486"],["Switzerland","#7CB878"],["Germany","#89BB6B"],["Italy","#96BD60"],["Slovenia","#A3BE57"],["Sweden","#B1BD4E"],["Austria","#BDBB48"],["Czech Republic","#CAB843"],["Slovakia","#D3B23F"],["Romania","#DDAA3C"],["Finland","#E29E39"],["Brazil","#E69036"],["Peru","#E67F33"],["Colombia","#E56B2F"],["Mexico","#E1552B"],["USA","#DE3E27"],["Canada","#DB2823"]]}],"filters":["clade_membership","lineage","country","host","institution","region"],"panels":["tree","entropy"],"extensions":{"nextclade":{"clade_node_attrs":[{"name":"outbreak","displayName":"Outbreak","description":""},{"name":"lineage","displayName":"Lineage","description":""}]}}},"tree":{"name":"NODE_0000001","node_attrs":{"div":0,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{},"labels":{"clade":"B.1"}},"children":[{"name":"ref_in_coord","node_attrs":{"div":0,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000000","node_attrs":{"div":0,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T607-","T608-","T609-","T133177-","C133178-","T133179-","T133180-","T133181-","C133182-","T133183-","C133184-","A133185-","A133186-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A196615-","A196616-","A196617-"]}},"children":[{"name":"ON803424","node_attrs":{"div":0,"accession":"ON803424","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/ON803424/2022-05-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-2852/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON959131","node_attrs":{"div":0,"accession":"ON959131","author":{"author":"Gigante,C.M.,Ghinai,I.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.M.,Ghinai,I.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"strain_display":{"value":"USA/ON959131/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_IL001"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON808414","node_attrs":{"div":0,"accession":"ON808414","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"strain_display":{"value":"United Kingdom/ON808414/2022-05-15"},"host":{"value":"Homo sapiens"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"date":{"value":"2022-05-15"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"CVR_MPXV1b"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OQ503745","node_attrs":{"div":0,"accession":"OQ503745","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OQ503745/2022-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-104493/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON838940","node_attrs":{"div":0,"accession":"ON838940","author":{"author":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J.","value":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J."},"strain_display":{"value":"Spain/ON838940/2022-05-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"Hospital Universitario La Paz, Microbiology"},"date":{"value":"2022-05-20"},"lineage":{"value":"B.1"},"country":{"value":"Spain"},"strain":{"value":"4061"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035654","node_attrs":{"div":0,"accession":"OR035654","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035654/2022-05-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-05-30"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_48"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON959161","node_attrs":{"div":0,"accession":"ON959161","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/ON959161/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI147"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP415256","node_attrs":{"div":0,"accession":"OP415256","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415256/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_jTHLhj_9000307"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON649720","node_attrs":{"div":0,"accession":"ON649720","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/ON649720/2022-05-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0024/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR035669","node_attrs":{"div":0,"accession":"OR035669","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035669/2022-06-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-06-09"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_63"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON803438","node_attrs":{"div":0,"accession":"ON803438","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/ON803438/2022-05-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-20"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-2897/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON880422","node_attrs":{"div":0,"accession":"ON880422","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/ON880422/2022-05-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Rega Institute, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-05-27"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPX/UZ_REGA_6/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP382480","node_attrs":{"div":0,"accession":"OP382480","author":{"author":"Colson,P.","value":"Colson,P."},"strain_display":{"value":"France/OP382480/2022-07-04"},"host":{"value":"Homo sapiens"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-04"},"lineage":{"value":"B.1"},"country":{"value":"France"},"strain":{"value":"hMPXV-IHU00003"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON649879","node_attrs":{"div":0,"accession":"ON649879","author":{"author":"Israeli,O.,Guedj-Dana,Y.,Lazar,S.,Shifman,O.,Erez,N.,Weiss,S.,Paran,N.,Israely,T.,Schuster,O.,Zvi,A.,Beth-Din,A.,Cohen Gihon,I.","value":"Israeli,O.,Guedj-Dana,Y.,Lazar,S.,Shifman,O.,Erez,N.,Weiss,S.,Paran,N.,Israely,T.,Schuster,O.,Zvi,A.,Beth-Din,A.,Cohen Gihon,I."},"strain_display":{"value":"Israel/ON649879/2022-05-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel"},"date":{"value":"2022-05-20"},"lineage":{"value":"B.1"},"country":{"value":"Israel"},"strain":{"value":"MPXV_ISR001_2022"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP415195","node_attrs":{"div":0,"accession":"OP415195","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415195/2022-03-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-03-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_96X1Vd_9000217"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON880526","node_attrs":{"div":0,"accession":"ON880526","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/ON880526/2022-05-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-27"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-3100/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"ON676703","node_attrs":{"div":0,"accession":"ON676703","author":{"author":"Gigante,C.M.,Ventura,J.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y.","value":"Gigante,C.M.,Ventura,J.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y."},"strain_display":{"value":"USA/ON676703/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_CA001"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP205114","node_attrs":{"div":0,"accession":"OP205114","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205114/2022-05-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-05-16"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000152"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035704","node_attrs":{"div":0,"accession":"OR035704","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035704/2022-05-31"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-05-31"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_98"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G179023A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035664","node_attrs":{"div":0,"accession":"OR035664","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035664/2022-06-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-06-13"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_58"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON682267","node_attrs":{"div":0,"accession":"ON682267","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/ON682267/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI010"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP524011","node_attrs":{"div":0,"accession":"OP524011","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP524011/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI409"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR030931","node_attrs":{"div":0,"accession":"OR030931","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR030931/2022-07-15"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-15"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_20"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264443","node_attrs":{"div":0,"accession":"OR264443","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264443/2022-08-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-22"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"60_D"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C173173T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON843178","node_attrs":{"div":0,"accession":"ON843178","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/ON843178/2022-06-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-06-02"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0040/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP310057","node_attrs":{"div":0,"accession":"OP310057","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OP310057/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-089714/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON880419","node_attrs":{"div":0,"accession":"ON880419","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/ON880419/2022-05-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Rega Institute, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-05-27"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPX/UZ_REGA_3/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON649724","node_attrs":{"div":0,"accession":"ON649724","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/ON649724/2022-05-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"date":{"value":"2022-05-23"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0014/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"ON880421","node_attrs":{"div":0,"accession":"ON880421","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/ON880421/2022-05-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Rega Institute, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-05-27"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPX/UZ_REGA_5/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON631241","node_attrs":{"div":0,"accession":"ON631241","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/ON631241/2022-05-24"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia"},"date":{"value":"2022-05-24"},"lineage":{"value":"B.1"},"country":{"value":"Slovenia"},"strain":{"value":"2022/2 SLO"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035663","node_attrs":{"div":0,"accession":"OR035663","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035663/2022-06-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-06-09"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_57"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON782022","node_attrs":{"div":0,"accession":"ON782022","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.,Sironen,T.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.,Sironen,T."},"strain_display":{"value":"Finland/ON782022/2022-05-31"},"host":{"value":"Homo sapiens"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"date":{"value":"2022-05-31"},"lineage":{"value":"B.1"},"country":{"value":"Finland"},"strain":{"value":"MPX-42/Finland/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OR035655","node_attrs":{"div":0,"accession":"OR035655","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035655/2022-05-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-05-30"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_49"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON803437","node_attrs":{"div":0,"accession":"ON803437","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/ON803437/2022-05-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-20"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-2896/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR035658","node_attrs":{"div":0,"accession":"OR035658","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035658/2022-06-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-06-02"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_52"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP205069","node_attrs":{"div":0,"accession":"OP205069","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205069/2022-06-06"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-06"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000063"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264442","node_attrs":{"div":0,"accession":"OR264442","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264442/2022-08-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-22"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"60_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C173173T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON880516","node_attrs":{"div":0,"accession":"ON880516","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"strain_display":{"value":"Canada/ON880516/2022-06-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-02"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-3472/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"ON755040","node_attrs":{"div":0,"accession":"ON755040","author":{"author":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O.","value":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O."},"strain_display":{"value":"France/ON755040/2022-05-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"IRBA, D.DNRBC/D.2MI/U.BACT"},"date":{"value":"2022-05-20"},"lineage":{"value":"B.1"},"country":{"value":"France"},"strain":{"value":"MPXV_IRBA22-14"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035667","node_attrs":{"div":0,"accession":"OR035667","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035667/2022-06-24"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-06-24"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_61"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON803442","node_attrs":{"div":0,"accession":"ON803442","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/ON803442/2022-05-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-16"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-2967/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR035668","node_attrs":{"div":0,"accession":"OR035668","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035668/2022-06-24"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-06-24"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_62"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON563414","node_attrs":{"div":0,"accession":"ON563414","author":{"author":"Gigante,C.M.,Smole,S.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Brown,C.,Li,Y.","value":"Gigante,C.M.,Smole,S.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Brown,C.,Li,Y."},"strain_display":{"value":"USA/ON563414/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_MA001"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON585032","node_attrs":{"div":0,"accession":"ON585032","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/ON585032/2022-05-17"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"date":{"value":"2022-05-17"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0004/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A188351-"]}}},{"name":"ON585029","node_attrs":{"div":0,"accession":"ON585029","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/ON585029/2022-05-04"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"date":{"value":"2022-05-04"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0001/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G1180-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-"]}}},{"name":"OP160532","node_attrs":{"div":1,"accession":"OP160532","author":{"author":"Tutu van Furth AM,van der Kuip M,van Els AL,Fievez LC,van Rijckevorsel GG,van den Ouden A,Jonges M,Welkers MR,Welkers,M.,Jonges,M.","value":"Tutu van Furth AM,van der Kuip M,van Els AL,Fievez LC,van Rijckevorsel GG,van den Ouden A,Jonges M,Welkers MR,Welkers,M.,Jonges,M."},"strain_display":{"value":"Netherlands/OP160532/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1"},"country":{"value":"Netherlands"},"strain":{"value":"hMpxV/Netherlands/NH-AUMC-0001/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A148207T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G191845A","A196614-"],"OPG173":["E57D"]},"labels":{"aa":"OPG173: E57D"}}},{"name":"LC722946","node_attrs":{"div":3,"accession":"LC722946","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"strain_display":{"value":"Japan/LC722946/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Japan"},"strain":{"value":"MPXV/human/Japan/Tokyo/TKY220091/2022"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C13653T","C116100T","G150376A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG025":["D539N"],"OPG176":["D190N"]},"labels":{"aa":"OPG025: D539N; OPG176: D190N"}}},{"name":"OP150926","node_attrs":{"div":0,"accession":"OP150926","author":{"author":"Gigante,C.,Goldoft,M.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Holshue,M.,Li,Y.","value":"Gigante,C.,Goldoft,M.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Holshue,M.,Li,Y."},"strain_display":{"value":"USA/OP150926/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_PA001"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP133006","node_attrs":{"div":4,"accession":"OP133006","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"strain_display":{"value":"Austria/OP133006/2022-07-06"},"host":{"value":"Homo sapiens"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"date":{"value":"2022-07-06"},"lineage":{"value":"B.1"},"country":{"value":"Austria"},"strain":{"value":"hMPXV/Austria/MUW1532243/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A28532-","C122511T","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","G151801A","C153984T","G169886A","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG044":["M148-"],"OPG143":["E269K"],"OPG178":["G98E"],"OPG197":["E73K"]},"labels":{"aa":"OPG044: M148-; OPG143: E269K; OPG178: G98E; OPG197: E73K"}}},{"name":"OP133007","node_attrs":{"div":2,"accession":"OP133007","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"strain_display":{"value":"Austria/OP133007/2022-07-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"date":{"value":"2022-07-22"},"lineage":{"value":"B.1"},"country":{"value":"Austria"},"strain":{"value":"hMPXV/Austria/MUW1536480/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A28532-","G32715A","G110407A","T133099-","T133100-","T133101-","T133102-","A173189G","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG044":["M148-"],"OPG049":["S146F"]},"labels":{"aa":"OPG044: M148-; OPG049: S146F"}}},{"name":"OP120937","node_attrs":{"div":1,"accession":"OP120937","author":{"author":"Aja-Macaya,P.,Rumbo-Feal,S.,Poza,M.,Canizares,A.,Vallejo,J.A.,Bou,G.","value":"Aja-Macaya,P.,Rumbo-Feal,S.,Poza,M.,Canizares,A.,Vallejo,J.A.,Bou,G."},"strain_display":{"value":"Spain/OP120937/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Biomedical research institute (INIBIC), Microbiology"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"Spain"},"strain":{"value":"MP01CHUAC"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G150330A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP013013","node_attrs":{"div":0,"accession":"OP013013","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I."},"strain_display":{"value":"Canada/OP013013/2022-06-10"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-10"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-3658/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP013004","node_attrs":{"div":1,"accession":"OP013004","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I."},"strain_display":{"value":"Canada/OP013004/2022-06-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-07"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-3518/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C40275T"],"OPG058":["D54N"]},"labels":{"aa":"OPG058: D54N"}}},{"name":"OP013015","node_attrs":{"div":1,"accession":"OP013015","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I."},"strain_display":{"value":"Canada/OP013015/2022-06-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-13"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-3674/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A32469G"],"OPG049":["V228A"]},"labels":{"aa":"OPG049: V228A"}}},{"name":"OP022171","node_attrs":{"div":0,"accession":"OP022171","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP022171/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_6"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179208C","-179209A","-179210T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"ON959134","node_attrs":{"div":1,"accession":"ON959134","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"strain_display":{"value":"USA/ON959134/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_NY003"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C98368T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON954773","node_attrs":{"div":2,"accession":"ON954773","author":{"author":"Gigante,C.M.,Ventura,J.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y.","value":"Gigante,C.M.,Ventura,J.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y."},"strain_display":{"value":"USA/ON954773/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_CA002"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G70190A","G83568A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG089":["E109K"],"OPG105":["A815T"]},"labels":{"aa":"OPG089: E109K; OPG105: A815T"}}},{"name":"ON880543","node_attrs":{"div":3,"accession":"ON880543","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/ON880543/2022-06-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-02"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-3357/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C17810T","G62130A","C157792T","A196614-"],"OPG030":["M8I"]},"labels":{"aa":"OPG030: M8I"}}},{"name":"ON880525","node_attrs":{"div":0,"accession":"ON880525","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/ON880525/2022-05-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-25"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-3086/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"ON843169","node_attrs":{"div":0,"accession":"ON843169","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/ON843169/2022-05-26"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-05-26"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0034/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON872184","node_attrs":{"div":5,"accession":"ON872184","author":{"author":"Fletcher,N.,Gonzalez,G.,Meredith,L.,Purves,K.,Carr,M.,Dean,J.,Keogan,B.,Crowley,B.,Lyons,F.,O'Reilly,S.,Gautier,V.,Mallon,P.,Gordon,S.,Connell,J.,De Gascun,C.F.","value":"Fletcher,N.,Gonzalez,G.,Meredith,L.,Purves,K.,Carr,M.,Dean,J.,Keogan,B.,Crowley,B.,Lyons,F.,O'Reilly,S.,Gautier,V.,Mallon,P.,Gordon,S.,Connell,J.,De Gascun,C.F."},"strain_display":{"value":"Ireland/ON872184/2022-05-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"University College Dublin, National Virus Reference Laboratory"},"date":{"value":"2022-05-30"},"lineage":{"value":"B.1"},"country":{"value":"Ireland"},"strain":{"value":"WA-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T48785C","G49636A","C50017T","T72809C","G178541A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG068":["G479E"],"OPG069":["T11I"],"OPG092":["K47E"]},"labels":{"aa":"OPG068: G479E; OPG069: T11I; OPG092: K47E"}}},{"name":"ON808416","node_attrs":{"div":1,"accession":"ON808416","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"strain_display":{"value":"United Kingdom/ON808416/2022-05-15"},"host":{"value":"Homo sapiens"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"date":{"value":"2022-05-15"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"CVR_MPXV1d"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G20576A","T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"ON843164","node_attrs":{"div":0,"accession":"ON843164","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/ON843164/2022-05-18"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-05-18"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0037/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C133103T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON838939","node_attrs":{"div":2,"accession":"ON838939","author":{"author":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J.","value":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J."},"strain_display":{"value":"Spain/ON838939/2022-06-06"},"host":{"value":"Homo sapiens"},"institution":{"value":"Hospital Universitario La Paz, Microbiology"},"date":{"value":"2022-06-06"},"lineage":{"value":"B.1"},"country":{"value":"Spain"},"strain":{"value":"8887"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G90838A","G94328A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG111":["D192N"]},"labels":{"aa":"OPG111: D192N"}}},{"name":"ON808415","node_attrs":{"div":0,"accession":"ON808415","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"strain_display":{"value":"United Kingdom/ON808415/2022-05-15"},"host":{"value":"Homo sapiens"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"date":{"value":"2022-05-15"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"CVR_MPXV1c"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"ON803444","node_attrs":{"div":1,"accession":"ON803444","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/ON803444/2022-05-24"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-24"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-2969/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G21069A"]}}},{"name":"ON803440","node_attrs":{"div":0,"accession":"ON803440","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/ON803440/2022-05-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-22"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-2954/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON803436","node_attrs":{"div":0,"accession":"ON803436","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/ON803436/2022-05-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-20"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-2894/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G143768-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG165":["G85-"]},"labels":{"aa":"OPG165: G85-"}}},{"name":"ON803435","node_attrs":{"div":3,"accession":"ON803435","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/ON803435/2022-05-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-20"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-2893/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C24731T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T152384A","C153104T"],"OPG040":["D250N"],"OPG180":["S138F"]},"labels":{"aa":"OPG040: D250N; OPG180: S138F"}}},{"name":"ON803416","node_attrs":{"div":0,"accession":"ON803416","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/ON803416/2022-05-17"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-17"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-2835/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON780016","node_attrs":{"div":0,"accession":"ON780016","author":{"author":"Rueca,M.,Giombini,E.,Gruber,C.E.M.,Gramigna,G.,Mazzotta,V.,Carletti,F.,Lapa,D.,Pittalis,S.,Puro,V.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F.","value":"Rueca,M.,Giombini,E.,Gruber,C.E.M.,Gramigna,G.,Mazzotta,V.,Carletti,F.,Lapa,D.,Pittalis,S.,Puro,V.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F."},"strain_display":{"value":"Italy/ON780016/2022-05-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"},"country":{"value":"Italy"},"strain":{"value":"INMI-Pt3"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A"]}}},{"name":"ON745215","node_attrs":{"div":0,"accession":"ON745215","author":{"author":"Giombini,E.,Gruber,C.E.M.,Rueca,M.,Gramigna,G.,VIta,S.,Carletti,F.,D'Abramo,A.,Lapa,D.,Puro,V.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Specchiarello,E.,Vairo,F.,Vaia,F.,Garbuglia,A.R.,Nicastri,E.,Antinori,A.,GIrardi,E.,Maggi,F.","value":"Giombini,E.,Gruber,C.E.M.,Rueca,M.,Gramigna,G.,VIta,S.,Carletti,F.,D'Abramo,A.,Lapa,D.,Puro,V.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Specchiarello,E.,Vairo,F.,Vaia,F.,Garbuglia,A.R.,Nicastri,E.,Antinori,A.,GIrardi,E.,Maggi,F."},"strain_display":{"value":"Italy/ON745215/2022-05-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"},"country":{"value":"Italy"},"strain":{"value":"INMI-Pt2"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T591A","A592-","T593-","T595A","-607T","-608T","-609T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A"]}}},{"name":"ON745225","node_attrs":{"div":1,"accession":"ON745225","author":{"author":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"strain_display":{"value":"Spain/ON745225/2022-05-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"HGUGM, Microbial Genomics"},"date":{"value":"2022-05-27"},"lineage":{"value":"B.1"},"country":{"value":"Spain"},"strain":{"value":"MpxV/Spain/MD-HGUGM-66649483/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G50151A","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG069":["D56N"]},"labels":{"aa":"OPG069: D56N"}}},{"name":"ON694341","node_attrs":{"div":1,"accession":"ON694341","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/ON694341/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI012"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G168174A"]}}},{"name":"ON676708","node_attrs":{"div":14,"accession":"ON676708","author":{"author":"Gigante,C.M.,Myers,R.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Blythe,D.,Li,Y.","value":"Gigante,C.M.,Myers,R.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Blythe,D.,Li,Y."},"strain_display":{"value":"USA/ON676708/2021-11-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2021-11-XX"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2021_MD"},"region":{"value":"North America"},"clade_membership":{"value":"outgroup"}},"branch_attrs":{"mutations":{"nuc":["A3111G","T39139C","A73239G","A74205G","A77383G","C79348T","T84587C","C86979T","C133714T","T150469C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C151461A","A155795G","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","A170262G","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T183519C","T194099C"],"OPG057":["K353E"],"OPG093":["N88D"],"OPG094":["I142M"],"OPG098":["K162E"],"OPG176":["Y221H"],"OPG197":["T34-","D35-"],"OPG210":["S722P"]},"labels":{"aa":"OPG057: K353E; OPG093: N88D; OPG094: I142M; OPG098: K162E; OPG176: Y221H; OPG197: T34-, D35-; OPG210: S722P","clade":"outgroup"}}},{"name":"ON682263","node_attrs":{"div":0,"accession":"ON682263","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Michel,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Michel,A."},"strain_display":{"value":"Germany/ON682263/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI03"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON676706","node_attrs":{"div":0,"accession":"ON676706","author":{"author":"Gigante,C.M.,Atkinson,A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Murray,J.,Li,Y.","value":"Gigante,C.M.,Atkinson,A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Murray,J.,Li,Y."},"strain_display":{"value":"USA/ON676706/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_UT002"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","T133102-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON676705","node_attrs":{"div":1,"accession":"ON676705","author":{"author":"Gigante,C.M.,Atkinson,A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Murray,J.,Li,Y.","value":"Gigante,C.M.,Atkinson,A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Murray,J.,Li,Y."},"strain_display":{"value":"USA/ON676705/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_UT001"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G28330A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG044":["M80I"]},"labels":{"aa":"OPG044: M80I"}}},{"name":"ON676704","node_attrs":{"div":2,"accession":"ON676704","author":{"author":"Gigante,C.M.,Lee,P.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y."},"strain_display":{"value":"USA/ON676704/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_FL002"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C127628T","C133864T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG149":["P145S"]},"labels":{"aa":"OPG149: P145S"}}},{"name":"ON649708","node_attrs":{"div":0,"accession":"ON649708","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/ON649708/2022-05-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0023/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"ON649711","node_attrs":{"div":0,"accession":"ON649711","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/ON649711/2022-05-18"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"date":{"value":"2022-05-18"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0026/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"ON649716","node_attrs":{"div":1,"accession":"ON649716","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/ON649716/2022-05-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"date":{"value":"2022-05-23"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0016/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C162826T"],"OPG188":["H411Y"]},"labels":{"aa":"OPG188: H411Y"}}},{"name":"ON649709","node_attrs":{"div":0,"accession":"ON649709","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/ON649709/2022-05-18"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"date":{"value":"2022-05-18"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0028/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"ON644344","node_attrs":{"div":0,"accession":"ON644344","author":{"author":"Licastro,D.,DeGasperi,M.,Negri,C.,Piscianz,E.,Koncan,R.,Dal Monego,S.,Segat,L.,D'Agaro,P.","value":"Licastro,D.,DeGasperi,M.,Negri,C.,Piscianz,E.,Koncan,R.,Dal Monego,S.,Segat,L.,D'Agaro,P."},"strain_display":{"value":"Italy/ON644344/2022-05-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"Genomics & Epigenomics, AREA Science Park, Italy"},"date":{"value":"2022-05-25"},"lineage":{"value":"B.1"},"country":{"value":"Italy"},"strain":{"value":"MPXV_FVG-ITA_01_2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C334-","A335-","C133077T","T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T173317-","G173318-","G173319-","G173320-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON622720","node_attrs":{"div":0,"accession":"ON622720","author":{"author":"Laubscher,F.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Schibler,M.,Kaiser,L.,Renzoni,A."},"strain_display":{"value":"Switzerland/ON622720/2022-05-24"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratory of Viorology, University Hospital of Geneva, Switzerland"},"date":{"value":"2022-05-24"},"lineage":{"value":"B.1"},"country":{"value":"Switzerland"},"strain":{"value":"MPXV-CH-38156923/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON622712","node_attrs":{"div":1,"accession":"ON622712","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/ON622712/2022-05-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"Microbiology, Immunology & Transplantation, KU Leuven, Rega Institute, Belgium"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPX/UZ_REGA_1/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C46125T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG065":["R120K"]},"labels":{"aa":"OPG065: R120K"}}},{"name":"ON619838","node_attrs":{"div":2,"accession":"ON619838","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/ON619838/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Research & Evaluation, UKHSA, UK"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_4"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C147011T","G172095A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"ON622713","node_attrs":{"div":1,"accession":"ON622713","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/ON622713/2022-05-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"Microbiology, Immunology & Transplantation, KU Leuven, Rega Institute, Belgium"},"date":{"value":"2022-05-22"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPX/UZ_REGA_2/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C4629T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G192581A"]}}},{"name":"ON619836","node_attrs":{"div":2,"accession":"ON619836","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/ON619836/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Research & Evaluation, UKHSA, UK"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_2"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C7259T","C33832T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG052":["R55Q"]},"labels":{"aa":"OPG052: R55Q"}}},{"name":"ON619835","node_attrs":{"div":0,"accession":"ON619835","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/ON619835/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Research & Evaluation, UKHSA, UK"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_1"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179179T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"ON614676","node_attrs":{"div":0,"accession":"ON614676","author":{"author":"Gruber,C.E.M.,Rueca,M.,Gramigna,G.,Carletti,F.,Butera,O.,Fabeni,L.,Specchiarello,E.,Meschi,S.,Colavita,F.,Minosse,C.,Francalancia,M.,Lapa,D.,Garbuglia,A.R.,Giombini,E.","value":"Gruber,C.E.M.,Rueca,M.,Gramigna,G.,Carletti,F.,Butera,O.,Fabeni,L.,Specchiarello,E.,Meschi,S.,Colavita,F.,Minosse,C.,Francalancia,M.,Lapa,D.,Garbuglia,A.R.,Giombini,E."},"strain_display":{"value":"Italy/ON614676/2022-05-18"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratory of Virology, INMI Lazzaro Spallanzani IRCCS, Italy"},"date":{"value":"2022-05-18"},"lineage":{"value":"B.1"},"country":{"value":"Italy"},"strain":{"value":"INMI-Pt1"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"ON615424","node_attrs":{"div":2,"accession":"ON615424","author":{"author":"Oude Munnink,B.B.,Boter,M.,Wellers,B.,Molenkamp,R.,Sikkema,R.S.,Koopmans,M.","value":"Oude Munnink,B.B.,Boter,M.,Wellers,B.,Molenkamp,R.,Sikkema,R.S.,Koopmans,M."},"strain_display":{"value":"Netherlands/ON615424/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Virology, Erasmus Medical Centre, The Netherlands"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"Netherlands"},"strain":{"value":"MPXV_2022_NL001"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155611A","G171003A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","G179362-","G179363-","-196615A"],"OPG199":["E6K"]},"labels":{"aa":"OPG199: E6K"}}},{"name":"ON595760","node_attrs":{"div":0,"accession":"ON595760","author":{"author":"Laubscher,F.,Chudzinski,V.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinski,V.,Schibler,M.,Kaiser,L.,Renzoni,A."},"strain_display":{"value":"Switzerland/ON595760/2022-05-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratory of Viorology, University Hospital of Geneva, Switzerland"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"},"country":{"value":"Switzerland"},"strain":{"value":"MPXV-CH-38134631/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","T133101-","T133102-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"]}}},{"name":"OP351278","node_attrs":{"div":1,"accession":"OP351278","author":{"author":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T.","value":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T."},"strain_display":{"value":"USA/OP351278/2022-06-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"date":{"value":"2022-06-14"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV22/human/USA-OK-21"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C75264T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"OP341487","node_attrs":{"div":4,"accession":"OP341487","author":{"author":"Welkers,M.,Jonges,M.,de Regt,M.,Ooijevaar,R.,Wagemakers,A.","value":"Welkers,M.,Jonges,M.,de Regt,M.,Ooijevaar,R.,Wagemakers,A."},"strain_display":{"value":"Netherlands/OP341487/2022-08-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention"},"date":{"value":"2022-08-05"},"lineage":{"value":"B.1"},"country":{"value":"Netherlands"},"strain":{"value":"hMpxV/Netherlands/NH-AUMC-0060/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C96773T","C109432T","C114985T","C142356T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG117":["S242L"],"OPG129":["D525N"],"OPG133":["D238N"],"OPG163":["S52F"]},"labels":{"aa":"OPG117: S242L; OPG129: D525N; OPG133: D238N; OPG163: S52F"}}},{"name":"OP324523","node_attrs":{"div":0,"accession":"OP324523","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP324523/2022-06-24"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-06-24"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0213/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP324489","node_attrs":{"div":1,"accession":"OP324489","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP324489/2022-06-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-06-30"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0174/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C143277T","C146816T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG164":["S167F"]},"labels":{"aa":"OPG164: S167F"}}},{"name":"OP324465","node_attrs":{"div":2,"accession":"OP324465","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP324465/2022-07-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-07"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0148/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G11924A","G41652A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG023":["S326L"],"OPG061":["S78F"]},"labels":{"aa":"OPG023: S326L; OPG061: S78F"}}},{"name":"OP324483","node_attrs":{"div":3,"accession":"OP324483","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP324483/2022-07-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-03"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0168/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C74000T","C135738T","C137574T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG094":["S74L"],"OPG153":["E32K"]},"labels":{"aa":"OPG094: S74L; OPG153: E32K"}}},{"name":"OP324462","node_attrs":{"div":1,"accession":"OP324462","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP324462/2022-07-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-07"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0143/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C87017T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG108":["D15N"]},"labels":{"aa":"OPG108: D15N"}}},{"name":"OP270028","node_attrs":{"div":5,"accession":"OP270028","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/OP270028/2022-07-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-07-07"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-4038/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G43708A","C133362T","G134674A","G134755A","G148453A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG064":["Q731*"],"OPG174":["R315C"]},"labels":{"aa":"OPG064: Q731*; OPG174: R315C"}}},{"name":"OP245358","node_attrs":{"div":1,"accession":"OP245358","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP245358/2022-07-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-14"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"MPX/PT0125/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C115572T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG133":["R42Q"]},"labels":{"aa":"OPG133: R42Q"}}},{"name":"OP245359","node_attrs":{"div":0,"accession":"OP245359","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP245359/2022-07-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-14"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"MPX/PT0126/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON645312","node_attrs":{"div":0,"accession":"ON645312","author":{"author":"Alcolea-Medina,A.,Charalampous,T.,Snell,L.B.,Batra,R.,Edgeworth,J.D.","value":"Alcolea-Medina,A.,Charalampous,T.,Snell,L.B.,Batra,R.,Edgeworth,J.D."},"strain_display":{"value":"United Kingdom/ON645312/2022-05-11"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centre for Clinical Infection & Diagnostics Research, Kings College London, St Thomas Hospital, UK"},"date":{"value":"2022-05-11"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_GSTT_Patient1"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T600-","T601-","T602-","T603-","T604-","T605-","T606-","T622-","G2239-","A2240-","C2241-","C4693-","T4694-","T4695-","A4696-","A4697-","C4698-","T4699-","A4700-","A4701-","C4702-","T4703-","T4704-","A4705-","T4706-","G4707-","A4708-","C4709-","T4710-","T4711-","A4712-","A4713-","C4714-","T4715-","A4716-","A4717-","C4718-","T4719-","T4720-","A4721-","T4722-","G4723-","A4724-","C4725-","T4726-","T4727-","A4728-","A4729-","C4730-","T4731-","A4732-","A4733-","C4734-","T4735-","T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","A4748-","A4749-","C4750-","T4751-","T4752-","A4753-","T4754-","G4755-","A4756-","C4757-","T4758-","T4759-","A4760-","A4761-","C4762-","T4763-","A4764-","A4765-","C4766-","T4767-","T4768-","A4769-","T4770-","G4771-","A4772-","C4773-","T4774-","T4775-","T6432-","C6433-","G7021-","C7022-","T7023-","C7024-","T7025-","C7026-","C7148-","T7149-","A7150-","T7151-","T7405-","A8054-","A8055-","T8328-","T8329-","A8421-","T8422-","A8423-","T8424-","A8471-","T8499-","T8919-","T8993-","A9282-","A9529-","A10280-","T10502-","A13276-","T13353-","A15549-","T15550-","A15872-","G16608-","T16609-","C16610-","A16611-","T16612-","C16613-","A18055-","C18056-","C18057-","A21081-","A23171-","A24310-","C24338-","A27114-","A28529-","A28530-","A28590-","G28591-","T28592-","G28593-","T28594-","T28595-","A28596-","A28597-","A28598-","A28599-","A28600-","A28601-","A28602-","T28603-","T28604-","A28605-","T28606-","C28607-","C28608-","T32194-","A32210-","C32211-","G32212-","A33199-","T33414-","T35571-","T41744-","T41935-","A43500-","A45122-","A46506-","C46507-","A46508-","T46596-","T46648-","A47576-","A47700-","C47701-","A48166-","G48167-","T48168-","C50500-","T50501-","T50575-","A50576-","A57277-","A58650-","A62041-","T62373-","T64752-","T66783-","A66843-","A71178-","T71901-","T76084-","T76085-","A76890-","T80846-","T80847-","A81969-","T87405-","T88836-","A89106-","A91705-","T94644-","T94645-","T97552-","T102749-","T103367-","T105360-","C106161-","C115267-","T116963-","T121121-","A123995-","A124727-","A127751-","A127752-","A128933-","G131762-","T132813-","T133088-","T133089-","T133090-","T133091-","T133092-","T133093-","T133094-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133493-","C133494-","G133495-","G133496-","T133497-","C133498-","C133499-","A133500-","T133501-","G133502-","T133503-","C133504-","T133505-","C133506-","C133507-","A133508-","T133509-","T133510-","G133511-","C133512-","T133513-","A133514-","C133515-","A133516-","C133517-","C133518-","A133519-","C133520-","C133521-","A133522-","T133523-","T133524-","A133525-","G133526-","A133527-","T133528-","T133529-","T133530-","A133531-","C133532-","A133533-","G133534-","G133535-","C133536-","T133537-","G133538-","C133539-","T133540-","A133541-","G133542-","T133543-","T133544-","G133545-","T133546-","C133547-","G133548-","T133549-","T133550-","C133551-","G133552-","A133553-","G133554-","A133555-","T133556-","C133557-","A133558-","G133559-","A133560-","A133561-","A133562-","T133563-","A133564-","C133565-","G133566-","T133567-","G133568-","T133569-","T133570-","T133571-","T133572-","C133573-","T133574-","T133575-","G133576-","G133577-","A133578-","A133579-","T133580-","G133581-","G133582-","A133583-","T133584-","T133585-","T133586-","C133587-","G133588-","T133589-","C133590-","G133591-","A133592-","T133593-","G133594-","T133595-","A133596-","C133597-","T133598-","T133599-","G133600-","T133601-","C133602-","A133603-","T133604-","G133605-","A133606-","T133607-","T133608-","G133609-","G133610-","C133611-","A133612-","T133613-","C133614-","G133615-","A133616-","A133617-","A133618-","C133619-","A133620-","C133621-","T133622-","T133623-","A133624-","T133625-","T133626-","A133627-","A133628-","G133629-","T133630-","T133631-","C133632-","T133633-","T133634-","T133635-","T133636-","T133637-","T133638-","T133639-","C133640-","A133641-","A133642-","T133643-","T133644-","C133645-","T133646-","A133647-","C133648-","G133649-","A133650-","T133651-","T133652-","T133653-","T133654-","A133655-","T133656-","T133657-","T133658-","C133659-","T133660-","T133661-","T133662-","C133663-","G133664-","C133665-","G133666-","A133667-","G133668-","T133669-","C133670-","A133671-","A133672-","T133673-","T133674-","C133675-","C133676-","C133677-","T133678-","C133679-","C133680-","T133681-","G133682-","T133683-","A133684-","G133685-","T133686-","A133687-","A133688-","C133689-","T133690-","A133691-","T133692-","C133693-","A133694-","G133695-","T133696-","T133697-","T133698-","T133699-","G133700-","T133701-","C133702-","A133703-","G133704-","A133705-","T133706-","T133707-","C133708-","A133709-","C133710-","G133711-","C133712-","T133713-","C133714-","T133715-","C133716-","T133717-","A133718-","C133719-","G133720-","T133721-","A133722-","G133723-","A133724-","C133725-","T133726-","T133727-","T133728-","C133729-","T133730-","T133731-","G133732-","T133733-","A133734-","A133735-","G133736-","T133737-","T133738-","A133739-","C133740-","T133741-","A133742-","A133743-","T133744-","T133745-","T133746-","G133747-","T133748-","T133749-","C133750-","C133751-","C133752-","T133753-","G133754-","G133755-","C133756-","A133757-","T133758-","T133759-","A133760-","C133761-","C133762-","G133763-","A133764-","G133765-","T133766-","T133767-","C133768-","A133769-","G133770-","T133771-","T133772-","T133773-","T133774-","A133775-","T133776-","A133777-","T133778-","G133779-","C133780-","C133781-","G133782-","A133783-","A133784-","T133785-","A133786-","G133787-","A133788-","G133789-","T133790-","T133791-","C133792-","T133793-","G133794-","A133795-","T133796-","T133797-","C133798-","A133799-","T133800-","C133801-","C133802-","T133803-","T133804-","T133805-","G133806-","A133807-","G133808-","A133809-","A133810-","G133811-","A133812-","T133813-","C133814-","T133815-","C133816-","T133817-","A133818-","G133819-","C133820-","G133821-","A133822-","T133823-","C133824-","G133825-","T133826-","T133827-","C133828-","A133829-","A133830-","G133831-","A133832-","T133833-","C133834-","C133835-","C133836-","T133837-","G133838-","A133839-","T133840-","T133841-","C133842-","T133843-","A133844-","G133845-","T133846-","C133847-","T133848-","T133849-","T133850-","A133851-","G133852-","C133853-","C133854-","T133855-","A133856-","T133857-","T133858-","T133859-","A133860-","C133861-","C133862-","T133863-","C133864-","C133865-","T133866-","C133867-","A133868-","G133869-","A133870-","A133871-","G133872-","A133873-","T133874-","G133875-","C133876-","T133877-","C133878-","C133879-","G133880-","T133881-","T133882-","A133883-","C133884-","C133885-","G133886-","T133887-","T133888-","T133889-","T133890-","T133891-","A133892-","C133893-","A133894-","A133895-","T133896-","C133897-","G133898-","T133899-","T133900-","A133901-","A133902-","G133903-","A133904-","T133905-","G133906-","T133907-","C133908-","T133909-","A133910-","T133911-","C133912-","A133913-","A133914-","G133915-","A133916-","T133917-","C133918-","C133919-","A133920-","T133921-","G133922-","A133923-","T133924-","T133925-","C133926-","T133927-","A133928-","T133929-","C133930-","T133931-","C133932-","T133933-","T133934-","T133935-","T133936-","C133937-","C133938-","A133939-","T133940-","A133941-","T133942-","C133943-","A133944-","G133945-","T137886-","A138474-","T139429-","T139430-","G139431-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","A142755-","G143459-","A145892-","T145979-","A145980-","A145981-","C146084-","G146085-","T146131-","A146863-","T146864-","T146884-","T146885-","T146886-","A146887-","T146888-","A146889-","T146890-","T146891-","T146892-","T146893-","A146894-","T146895-","A146969-","A148139-","A148211-","T148344-","T150539-","G151022-","A151023-","C151024-","A151025-","T151026-","A151043-","A152267-","T152268-","T152269-","A152675-","A152676-","A153424-","C154354-","T154355-","T155424-","A156210-","T156371-","A156372-","C156373-","T156374-","G156375-","A156376-","C156377-","T156378-","A156379-","C156380-","A156381-","T156382-","G156383-","T156384-","A156385-","C156386-","T156387-","A156388-","T156389-","T156390-","T156391-","T156392-","A156393-","C156394-","A156395-","T156396-","T156397-","A156398-","C156399-","T156400-","A156401-","C156402-","A156403-","T156404-","T156405-","G156406-","G156407-","C156408-","T156409-","A156410-","C156411-","G156412-","G156413-","C156414-","A156415-","T156416-","A156417-","T156418-","A156419-","T156420-","A156421-","C156422-","C156423-","T156424-","A156425-","T156426-","T156427-","T156428-","C156429-","G156430-","T156431-","C156432-","A156433-","C156434-","T156435-","T156436-","C156437-","C156438-","A156439-","C156440-","A156441-","C156442-","G156443-","C156444-","T156445-","C156446-","C156447-","G156448-","G156449-","T156450-","A156451-","A156452-","A156453-","C156454-","G156455-","G156456-","G156457-","T156458-","G156459-","T156460-","C156461-","A156462-","T156463-","G156464-","T156465-","G156466-","A156467-","C156468-","G156469-","A156470-","G156471-","G156472-","G156473-","A156474-","G156475-","A156476-","A156477-","T156478-","C156479-","T156480-","T156481-","G156482-","A156483-","T156484-","A156485-","A156486-","G156487-","A156488-","G156489-","G156490-","C156491-","A156492-","T156493-","A156494-","A156495-","T156496-","C156497-","A156498-","A156499-","T156500-","G156501-","T156502-","T156503-","G156504-","T156505-","A156506-","A156507-","T156508-","C156509-","C156510-","G156511-","A156512-","T156513-","G156514-","T156515-","C156516-","C156517-","A156518-","C156519-","C156520-","T156521-","G156522-","G156523-","A156524-","G156525-","A156526-","A156527-","T156528-","T156529-","T156530-","G156531-","C156532-","C156533-","A156534-","A156535-","G156536-","G156537-","T156538-","C156539-","A156540-","G156541-","A156542-","T156543-","G156544-","T156545-","A156546-","G156547-","A156548-","G156549-","T156550-","T156551-","G156552-","G156553-","T156554-","A156555-","G156556-","T156557-","G156558-","A156559-","T156560-","A156561-","A156562-","C156563-","A156564-","C156565-","A156566-","A156567-","A156568-","A156569-","T156570-","G156571-","T156572-","G156573-","A156574-","A156575-","C156576-","A156577-","C156578-","T156579-","G156580-","C156581-","C156582-","C156583-","A156584-","C156585-","C156586-","T156587-","C156588-","A156589-","T156590-","A156591-","C156592-","A156593-","T156594-","A156595-","T156596-","A156597-","C156598-","C156599-","G156600-","C156601-","A156602-","A156603-","T156604-","C156605-","C156606-","C156607-","C156608-","A156609-","A156610-","T156611-","T156612-","A156613-","T156614-","T156615-","C156616-","T156617-","A156618-","A156619-","T156620-","A156621-","G156622-","A156623-","T156624-","G156625-","T156626-","C156627-","A156628-","T156629-","C156630-","A156631-","A156632-","T156633-","G156634-","T156635-","A156636-","G156637-","A156638-","A156639-","A156640-","A156641-","T156642-","G156643-","C156644-","C156645-","C156646-","A156647-","A156648-","C156649-","A156650-","G156651-","G156652-","A156653-","T156654-","C156655-","A156656-","T156657-","T156658-","T156659-","G156660-","A156661-","T156662-","A156663-","A156664-","G156665-","G156666-","T156667-","A156668-","A156669-","A156670-","G156671-","T156672-","G156673-","T156674-","A156675-","C156676-","C156677-","G156678-","G156679-","A156680-","A156681-","C156682-","A156683-","C156684-","A156685-","G156686-","A156687-","A156688-","C156689-","A156690-","A156691-","A156692-","T156693-","G156694-","T156695-","T156696-","C156697-","G156698-","T156699-","G156700-","T156701-","C156702-","A156703-","T156704-","C156705-","C156706-","T156707-","G156708-","G156709-","T156710-","T156711-","G156712-","G156713-","T156714-","A156715-","T156716-","A156717-","C156718-","G156719-","C156720-","T156721-","A156722-","C156723-","T156724-","G156725-","A156726-","T156727-","T156728-","C156729-","T156730-","T156731-","C156732-","A156733-","C156734-","A156735-","G156736-","A156737-","C156738-","T156739-","G156740-","A156741-","A156742-","G156743-","A156744-","T156745-","T156746-","G156747-","T156748-","C156749-","G156750-","A156751-","G156752-","A156753-","T156754-","T156755-","T156756-","G156757-","T156758-","G156759-","T156760-","A156761-","C156762-","C156763-","A156764-","A156765-","A156766-","A156767-","A156768-","A156769-","G156770-","G156771-","A156772-","G156773-","A156774-","T156775-","G156776-","T156777-","C156778-","C156779-","A156780-","T156781-","G156782-","C156783-","G156784-","G156785-","A156786-","T156787-","A156788-","C156789-","T156790-","T156791-","T156792-","G156793-","G156794-","T156795-","G156796-","G156797-","A156798-","A156799-","T156800-","A156801-","G156802-","A156803-","T156804-","G156805-","A156806-","A156807-","G156808-","G156809-","A156810-","A156811-","A156812-","T156813-","C156814-","C156815-","T156816-","A156817-","T156818-","T156819-","T156820-","G156821-","T156822-","A156823-","A156824-","A156825-","T156826-","C156827-","G156828-","T156829-","G156830-","T156831-","T156832-","G156833-","T156834-","G156835-","T156836-","T156837-","G156838-","G156839-","T156840-","G156841-","A156842-","A156843-","T156844-","A156845-","T156846-","T156847-","G156848-","C156849-","G156850-","A156851-","C156852-","T156853-","A156854-","C156855-","C156856-","T156857-","A156858-","C156859-","G156860-","T156861-","A156862-","A156863-","T156864-","T156865-","A156866-","T156867-","A156868-","G156869-","A156870-","C156871-","T156872-","T156873-","G156874-","A156875-","T156876-","C156877-","C156878-","A156879-","T156880-","T156881-","T156882-","C156883-","C156884-","T156885-","C156886-","C156887-","A156888-","T156889-","G156890-","C156891-","A156892-","A156893-","A156894-","C156895-","T156896-","A156897-","T156898-","C156899-","T156900-","A156901-","T156902-","C156903-","T156904-","A156905-","A156906-","A156907-","T156908-","G156909-","T156910-","A156911-","A156912-","T156913-","T156914-","A156915-","A156916-","T156917-","T156918-","A156919-","T156920-","G156921-","A156922-","T156923-","T156924-","T156925-","T156926-","G156927-","A156928-","T156929-","G156930-","A156931-","T156932-","A156933-","A156934-","T156935-","G156936-","T156937-","T156938-","A156939-","C156940-","C156941-","A156942-","T156943-","A156944-","C156945-","A156946-","T156947-","T156948-","A156949-","T156950-","A156951-","T156952-","C156953-","A156954-","C156955-","T156956-","A156957-","C156958-","T156959-","T156960-","G156961-","G156962-","T156963-","T156964-","A156965-","G156966-","T156967-","G156968-","T156969-","G156970-","T156971-","A156972-","T156973-","T156974-","A156975-","T156976-","T156977-","T156978-","A156979-","G156980-","T156981-","A156982-","T156983-","G156984-","G156985-","A156986-","A156987-","G156988-","A156989-","C156990-","C156991-","T156992-","A156993-","T156994-","T156995-","A156996-","A156997-","T156998-","A156999-","A157000-","T157001-","T157002-","A157003-","C157004-","T157005-","T157006-","A157007-","T157008-","C157009-","T157010-","T157011-","T157012-","T157013-","G157014-","A157015-","C157016-","G157017-","A157018-","T157019-","C157020-","T157021-","T157022-","G157023-","T157024-","T157025-","A157026-","T157027-","A157028-","A157029-","T157030-","T157031-","A157032-","T157033-","A157034-","A157035-","T157036-","A157037-","T157038-","A157039-","A157040-","A157041-","A157042-","A157043-","T157044-","A157045-","C157046-","T157047-","T157048-","A157049-","T157050-","G157051-","A157052-","C157053-","A157054-","T157055-","A157056-","G157057-","T157058-","A157059-","A157060-","C157061-","T157062-","C157063-","A157064-","T157065-","A157066-","A157067-","T157068-","T157069-","G157070-","C157071-","T157072-","G157073-","A157074-","C157075-","G157076-","C157077-","G157078-","A157079-","T157080-","A157081-","A157082-","A157083-","T157084-","T157085-","C157086-","G157087-","T157088-","A157089-","A157090-","T157091-","A157092-","A157093-","T157094-","C157095-","T157096-","G157097-","T157098-","T157099-","T157100-","T157101-","G157102-","T157103-","T157104-","C157105-","A157106-","A157107-","A157108-","T157109-","T157110-","T157111-","T157112-","T157113-","A157114-","T157115-","A157116-","A157117-","G157118-","G157119-","A157120-","A157121-","T157122-","C157123-","T157124-","A157125-","C157126-","A157127-","G157128-","G157129-","C157130-","A157131-","T157132-","A157133-","A157134-","A157135-","A157136-","A157137-","T157138-","A157139-","A157140-","A157141-","A157142-","A157143-","T157144-","A157145-","T157146-","A157147-","A157148-","T157149-","C157150-","T157151-","A157152-","T157153-","A157154-","A157155-","T157156-","A157157-","T157158-","A157159-","C157160-","T157161-","C157162-","T157163-","T157164-","A157165-","C157166-","A157167-","A157168-","C157169-","G157170-","C157171-","C157172-","A157173-","T157174-","C157175-","A157176-","T157177-","G157178-","A157179-","A157180-","T157181-","A157182-","G157183-","C157184-","A157185-","G157186-","T157187-","G157188-","A157189-","A157190-","T157191-","T157192-","A157193-","A157194-","T157195-","T157196-","G157197-","C157198-","T157199-","G157200-","T157201-","T157202-","A157203-","T157204-","T157205-","A157206-","T157207-","G157208-","G157209-","A157210-","T157211-","T157212-","T157213-","A157214-","G157215-","A157216-","A157217-","A157218-","T157219-","A157220-","G157221-","T157222-","G157223-","G157224-","A157225-","C157226-","G157227-","A157228-","T157229-","T157230-","T157231-","T157232-","G157233-","T157234-","G157235-","A157236-","T157237-","A157238-","T157239-","T157240-","A157241-","A157242-","T157243-","A157244-","T157245-","A157246-","G157247-","T157248-","T157249-","A157250-","T157251-","T157252-","A157253-","A157254-","T157255-","G157256-","A157257-","T157258-","G157259-","A157260-","A157261-","A157262-","G157263-","G157264-","A157265-","T157266-","A157267-","A157268-","A157269-","C157270-","G157271-","C157272-","G157273-","C157274-","A157275-","T157276-","A157277-","G157278-","A157279-","C157280-","T157281-","C157282-","A157283-","T157284-","C157285-","C157286-","T157287-","A157288-","T157289-","C157290-","T157291-","G157292-","G157293-","A157294-","G157295-","C157296-","C157297-","T157298-","C157299-","C157300-","G157301-","A157302-","A157303-","T157304-","A157305-","T157306-","T157307-","T157308-","T157309-","T157310-","T157311-","C157312-","C157313-","A157314-","T157315-","T157316-","C157317-","T157318-","G157319-","T157320-","T157321-","T157322-","T157323-","C157324-","C157325-","A157326-","A157327-","T157328-","A157329-","A157330-","T157331-","T157332-","T157333-","T157334-","A157335-","T157336-","C157337-","G157338-","A157339-","T157340-","T157341-","C157342-","T157343-","A157344-","A157345-","T157346-","G157347-","A157348-","A157349-","T157350-","A157351-","C157352-","G157353-","A157354-","A157355-","G157356-","T157357-","T157358-","A157359-","A157360-","T157361-","C157362-","T157363-","A157364-","A157365-","G157366-","T157367-","C157368-","A157369-","T157370-","T157371-","T157372-","A157373-","G157374-","A157375-","T157376-","T157377-","A157378-","T157379-","C157380-","A157381-","A157382-","A157383-","G157384-","T157385-","G157386-","T157387-","T157388-","A157389-","A157390-","C157391-","T157392-","A157393-","T157394-","T157395-","T157396-","G157397-","A157398-","T157399-","C157400-","G157401-","A157402-","T157403-","T157404-","A157405-","C157406-","A157407-","T157408-","T157409-","T157410-","A157411-","T157412-","G157413-","G157414-","G157415-","A157416-","T157417-","A157418-","C157419-","C157420-","T157421-","T157422-","T157423-","G157424-","A157425-","G157426-","C157427-","C157428-","T157429-","A157430-","A157431-","C157432-","T157433-","A157434-","A157435-","C157436-","A157437-","A157438-","T157439-","A157440-","A157441-","C157442-","G157443-","T157444-","G157445-","A157446-","A157447-","A157448-","T157449-","A157450-","T157451-","A157452-","T157453-","T157454-","C157455-","T157456-","T157457-","T157458-","C157459-","A157460-","A157461-","C157462-","C157463-","G157464-","C157465-","T157466-","G157467-","A157468-","T157469-","T157470-","T157471-","T157472-","T157473-","T157474-","T157475-","A157476-","C157477-","A157478-","A157479-","A157480-","T157481-","T157482-","G157483-","G157484-","A157485-","T157486-","C157487-","T157488-","G157489-","T157490-","C157491-","A157492-","T157493-","T157494-","A157495-","C157496-","T157497-","G157498-","A157499-","G157500-","T157501-","G157502-","C157503-","G157504-","A157505-","A157506-","A157507-","A157508-","A157509-","T157510-","A157511-","C157512-","A157513-","T157514-","A157515-","C157516-","T157517-","T157518-","A157519-","A157520-","A157521-","A157522-","A157523-","T157524-","C157525-","T157526-","T157527-","T157528-","G157529-","T157530-","T157531-","T157532-","T157533-","A157534-","G157535-","A157536-","A157537-","A157538-","C157539-","T157540-","G157541-","T157542-","A157543-","T157544-","C157545-","G157546-","A157547-","T157548-","T157549-","T157550-","C157551-","T157552-","A157553-","C157554-","A157555-","T157556-","A157557-","T157558-","A157559-","C157560-","G157561-","C157562-","T157563-","G157564-","A157565-","T157566-","A157567-","A157568-","A157569-","T157570-","A157571-","T157572-","A157573-","A157574-","T157575-","A157576-","A157577-","C157578-","A157579-","A157580-","G157581-","A157582-","A157583-","A157584-","A157585-","T157586-","A157587-","G157588-","A157589-","A157590-","T157591-","T157592-","A157593-","G157594-","C157595-","A157596-","T157597-","C157598-","G157599-","T157600-","T157601-","T157602-","A157603-","A157604-","C157605-","A157606-","C157607-","A157608-","A157609-","T157610-","A157611-","T157612-","T157613-","A157614-","C157615-","G157616-","A157617-","A157618-","A157619-","T157620-","A157621-","T157622-","T157623-","T157624-","T157625-","G157626-","A157627-","G157628-","A157629-","C157630-","T157631-","C157632-","A157633-","T157634-","C157635-","A157636-","A157637-","C157638-","A157639-","A157640-","T157641-","G157642-","A157643-","A157644-","A157645-","A157646-","C157647-","T157648-","T157649-","T157650-","A157651-","A157652-","A157653-","T157654-","A157655-","C157656-","T157657-","T157658-","A157659-","A157660-","C157661-","A157662-","G157663-","A157664-","G157665-","G157666-","A157667-","A157668-","T157669-","C157670-","A157671-","A157672-","T157673-","G157674-","A157675-","T157676-","A157677-","A157678-","A157679-","A157680-","A157681-","T157682-","T157683-","T157684-","T157685-","A157686-","A157687-","G157688-","C157689-","G157690-","A157691-","T157692-","G157693-","A157694-","T157695-","A157696-","T157697-","G157698-","T157699-","T157700-","A157701-","T157702-","A157703-","T157704-","A157705-","T157706-","A157707-","A157708-","A157709-","A157710-","A157711-","A157712-","T157713-","G157714-","A157715-","G157716-","G157717-","A157718-","T157719-","T157720-","T157721-","C157722-","A157723-","C157724-","C157725-","C157726-","C157727-","A157728-","C157729-","T157730-","G157731-","A157732-","T157733-","T157734-","C157735-","T157736-","C157737-","A157738-","T157739-","T157740-","A157741-","A157742-","A157743-","T157744-","G157745-","G157746-","T157747-","T157748-","A157749-","G157750-","A157751-","G157752-","A157753-","G157754-","T157755-","A157756-","C157757-","A157758-","C157759-","C157760-","A157761-","A157762-","C157763-","C157764-","A157765-","T157766-","G157767-","T157768-","A157769-","C157770-","C157771-","G157772-","T157773-","C157774-","G157775-","A157776-","G157777-","T157778-","T157779-","A157780-","C157781-","T157782-","T157783-","A157784-","G157785-","A157786-","T157787-","G157788-","C157789-","C157790-","T157791-","C157792-","A157793-","G157794-","A157795-","A157796-","T157797-","A157798-","T157799-","C157800-","A157801-","T157802-","T157803-","T157804-","C157805-","T157806-","T157807-","T157808-","C157809-","C157810-","C157811-","C157812-","A157813-","C157814-","A157815-","A157816-","G157817-","T157818-","T157819-","A157820-","T157821-","A157822-","A157823-","A157824-","A157825-","T157826-","C157827-","A157828-","C157829-","T157830-","T157831-","T157832-","A157833-","T157834-","A157835-","G157836-","T157837-","C157838-","A157839-","T157840-","C157841-","G157842-","A157843-","C157844-","T157845-","G157846-","G157847-","T157848-","T157849-","A157850-","G157851-","T157852-","T157853-","C157854-","A157855-","A157856-","T157857-","C157858-","T157859-","A157860-","C157861-","G157862-","A157863-","A157864-","T157865-","G157866-","T157867-","A157868-","T157869-","A157870-","A157871-","C157872-","A157873-","T157874-","T157875-","C157876-","T157877-","T157878-","A157879-","A157880-","A157881-","C157882-","A157883-","A157884-","T157885-","A157886-","T157887-","A157888-","G157889-","C157890-","A157891-","T157892-","T157893-","C157894-","T157895-","T157896-","G157897-","G157898-","A157899-","T157900-","A157901-","A157902-","A157903-","T157904-","C157905-","A157906-","T157907-","T157908-","T157909-","C157910-","C157911-","T157912-","A157913-","G157914-","A157915-","T157916-","A157917-","C157918-","C157919-","A157920-","T157921-","A157922-","T157923-","C157924-","A157925-","T157926-","C157927-","G157928-","A157929-","G157930-","T157931-","T157932-","G157933-","A157934-","T157935-","A157936-","T157937-","C157938-","T157939-","A157940-","T157941-","C157942-","G157943-","G157944-","T157945-","A157946-","T157947-","A157948-","A157949-","G157950-","T157951-","A157952-","A157953-","T157954-","T157955-","C157956-","A157957-","C157958-","A157959-","T157960-","G157961-","A157962-","T157963-","A157964-","A157965-","G157966-","A157967-","T157968-","T157969-","T157970-","C157971-","C157972-","A157973-","T157974-","A157975-","A157976-","A157977-","C157978-","T157979-","G157980-","C157981-","T157982-","A157983-","C157984-","A157985-","A157986-","T157987-","C157988-","A157989-","T157990-","A157991-","A157992-","A157993-","A157994-","A157995-","A157996-","A157997-","T157998-","T157999-","C158000-","A158001-","T158002-","G158003-","G158004-","G158005-","A158006-","A158007-","A158008-","T158009-","G158010-","A158011-","T158012-","A158013-","T158014-","C158015-","T158016-","T158017-","C158018-","A158019-","C158020-","G158021-","T158022-","A158023-","G158024-","A158025-","T158026-","A158027-","T158028-","A158029-","G158030-","G158031-","T158032-","G158033-","T158034-","A158035-","G158036-","T158037-","T158038-","T158039-","C158040-","G158041-","C158042-","A158043-","G158044-","T158045-","G158046-","A158047-","C158048-","C158049-","G158050-","T158051-","C158052-","C158053-","T158054-","G158055-","G158056-","A158057-","T158058-","A158059-","A158060-","T158061-","A158062-","T158063-","T158064-","A158065-","T158066-","C158067-","T158068-","A158069-","T158070-","A158071-","T158072-","G158073-","A158074-","T158075-","G158076-","G158077-","G158078-","T158079-","G158080-","G158081-","A158082-","T158083-","A158084-","T158085-","G158086-","A158087-","T158088-","C158089-","A158090-","G158091-","T158092-","C158093-","C158094-","C158095-","T158096-","G158097-","T158098-","A158099-","T158100-","A158101-","G158102-","A158103-","A158104-","G158105-","T158106-","T158107-","C158108-","A158109-","A158110-","A158111-","G158112-","G158113-","T158114-","T158115-","A158116-","T158117-","A158118-","G158119-","C158120-","G158121-","T158122-","A158123-","C158124-","A158125-","A158126-","T158127-","A158128-","C158129-","A158130-","T158131-","G158132-","T158133-","A158134-","C158135-","T158136-","A158137-","A158138-","T158139-","T158140-","C158141-","T158142-","T158143-","G158144-","G158145-","A158146-","T158147-","A158148-","T158149-","A158150-","T158151-","G158152-","A158153-","T158154-","A158155-","T158156-","A158157-","C158158-","C158159-","A158160-","G158161-","A158162-","G158163-","C158164-","T158165-","A158166-","A158167-","A158168-","A158169-","A158170-","T158171-","A158172-","T158173-","C158174-","A158175-","T158176-","C158177-","G158178-","T158179-","T158180-","C158181-","T158182-","A158183-","A158184-","T158185-","T158186-","G158187-","C158188-","G158189-","G158190-","A158191-","G158192-","G158193-","A158194-","G158195-","T158196-","T158197-","G158198-","C158199-","C158200-","A158201-","A158202-","T158203-","G158204-","A158205-","C158206-","G158207-","A158208-","A158209-","T158210-","A158211-","C158212-","A158213-","T158214-","T158215-","T158216-","A158217-","T158218-","T158219-","G158220-","T158221-","A158222-","T158223-","A158224-","G158225-","G158226-","C158227-","G158228-","G158229-","T158230-","A158231-","T158232-","A158233-","C158234-","G158235-","C158236-","G158237-","A158238-","T158239-","C158240-","A158241-","G158242-","G158243-","A158244-","G158245-","T158246-","C158247-","A158248-","T158249-","C158250-","G158251-","T158252-","T158253-","G158254-","A158255-","T158256-","A158257-","T158258-","C158259-","T158260-","A158261-","G158262-","T158263-","A158264-","T158265-","C158266-","G158267-","A158268-","T158269-","A158270-","G158271-","A158272-","T158273-","G158274-","G158275-","A158276-","A158277-","G158278-","C158279-","C158280-","A158281-","T158282-","C158283-","A158284-","A158285-","A158286-","A158287-","C158288-","C158289-","A158290-","T158291-","A158292-","T158293-","T158294-","G158295-","G158296-","C158297-","A158298-","G158299-","A158300-","A158301-","G158302-","T158303-","A158304-","T158305-","G158306-","C158307-","T158308-","A158309-","A158310-","A158311-","A158312-","T158313-","G158314-","T158315-","G158316-","C158317-","G158318-","A158319-","A158320-","C158321-","C158322-","A158323-","A158324-","A158325-","A158326-","T158327-","G158328-","T158329-","G158330-","A158331-","T158332-","A158333-","T158334-","G158335-","G158336-","G158337-","G158338-","T158339-","T158340-","G158341-","C158342-","G158343-","A158344-","T158345-","T158346-","T158347-","T158348-","A158349-","A158350-","A158351-","C158352-","G158353-","G158354-","A158355-","T158356-","T158357-","A158358-","A158359-","T158360-","A158361-","T158362-","A158363-","T158364-","G158365-","T158366-","C158367-","A158368-","T158369-","A158370-","G158371-","G158372-","T158373-","G158374-","G158375-","A158376-","G158377-","T158378-","C158379-","G158380-","T158381-","T158382-","A158383-","A158384-","A158385-","G158386-","G158387-","T158388-","G158389-","A158390-","C158391-","A158392-","C158393-","A158394-","C158395-","A158396-","T158397-","A158398-","T158399-","A158400-","C158401-","C158402-","A158403-","A158404-","C158405-","G158406-","C158407-","A158408-","C158409-","T158410-","A158411-","G158412-","A158413-","G158414-","A158415-","G158416-","T158417-","T158418-","T158419-","A158420-","T158421-","C158422-","A158423-","G158424-","A158425-","A158426-","G158427-","A158428-","T158429-","G158430-","G158431-","A158432-","T158433-","G158434-","G158435-","A158436-","T158437-","G158438-","A158439-","A158440-","T158441-","C158442-","A158443-","T158444-","C158445-","A158446-","A158447-","C158448-","G158449-","T158450-","C158451-","T158452-","T158453-","C158454-","C158455-","A158456-","A158457-","T158458-","A158459-","A158460-","A158461-","A158462-","A158463-","T158464-","G158465-","T158466-","C158467-","C158468-","A158469-","A158470-","T158471-","A158472-","T158473-","G158474-","T158475-","C158476-","G158477-","A158478-","C158479-","G158480-","A158481-","T158482-","T158483-","G158484-","T158485-","T158486-","C158487-","A158488-","T158489-","G158490-","C158491-","T158492-","G158493-","G158494-","A158495-","A158496-","A158497-","G158498-","A158499-","T158500-","T158501-","T158502-","A158503-","T158504-","A158505-","T158506-","A158507-","T158508-","C158509-","T158510-","A158511-","G158512-","A158513-","G158514-","G158515-","T158516-","T158517-","A158518-","C158519-","A158520-","A158521-","C158522-","A158523-","A158524-","T158525-","A158526-","G158527-","T158528-","A158529-","G158530-","T158531-","G158532-","T158533-","A158534-","G158535-","T158536-","T158537-","A158538-","A158539-","T158540-","G158541-","T158542-","A158543-","A158544-","T158545-","A158546-","T158547-","C158548-","G158549-","A158550-","A158551-","T158552-","C158553-","T158554-","A158555-","G158556-","T158557-","C158558-","C158559-","T158560-","T158561-","A158562-","G158563-","C158564-","T158565-","A158566-","T158567-","A158568-","A158569-","T158570-","C158571-","C158572-","G158573-","A158574-","T158575-","A158576-","T158577-","A158578-","T158579-","G158580-","A158581-","T158582-","G158583-","A158584-","A158585-","T158586-","G158587-","G158588-","A158589-","C158590-","C158591-","A158592-","A158593-","A158594-","T158595-","T158596-","A158597-","T158598-","C158599-","A158600-","T158601-","C158602-","A158603-","T158604-","T158605-","A158606-","A158607-","A158608-","T158609-","A158610-","T158611-","T158612-","C158613-","C158614-","T158615-","A158616-","G158617-","A158618-","A158619-","T158620-","T158621-","A158622-","A158623-","T158624-","C158625-","C158626-","T158627-","G158628-","C158629-","T158630-","C158631-","T158632-","A158633-","T158634-","G160043-","A162904-","A163207-","A163208-","C163209-","T163210-","A163211-","A163212-","C163213-","T163214-","T165054-","C165055-","T166656-","T166657-","T166712-","T168120-","T168214-","A168962-","A169025-","T169165-","A169581-","T169721-","C169722-","A169723-","G169724-","A169725-","T169726-","A169777-","G169778-","A169779-","A169780-","G169781-","A169782-","T169783-","A169784-","T169785-","C169786-","A169787-","T169788-","G169789-","A169790-","A169791-","T169792-","G169793-","A169794-","A169795-","A169796-","A170728-","T170903-","T170904-","G170918-","T172063-","T172086-","T172087-","T172667-","A173105-","T173106-","G173107-","G173108-","T173109-","A173110-","T173111-","G173112-","T173113-","C173114-","C173115-","C173116-","A173117-","A173118-","T173119-","A173120-","T173121-","T173122-","A173123-","A173124-","T173125-","G173126-","C173127-","A173128-","T173129-","T173130-","T173131-","A173132-","T173133-","T173134-","T173135-","C173136-","T173137-","A173138-","G173139-","T173140-","A173141-","A173142-","C173143-","G173144-","T173145-","A173146-","A173147-","A173148-","C173149-","A173150-","C173151-","A173152-","G173153-","A173154-","A173155-","T173156-","T173157-","A173158-","T173159-","A173160-","T173161-","G173162-","G173163-","A173164-","G173165-","C173166-","G173167-","G173168-","A173169-","C173170-","A173171-","T173172-","C173173-","G173174-","A173175-","C173176-","G173177-","C173178-","C173179-","T173180-","T173181-","A173182-","G173183-","A173184-","A173185-","A173186-","T173187-","A173188-","A173189-","G173190-","A173191-","G173192-","A173193-","C173194-","T173195-","T173196-","A173197-","A173198-","A173199-","C173200-","A173201-","A173202-","C173203-","G173204-","G173205-","A173206-","C173207-","A173208-","C173209-","C173210-","T173211-","G173212-","G173213-","A173214-","A173215-","T173216-","T173217-","A173218-","T173219-","T173220-","A173221-","C173222-","C173223-","A173224-","T173225-","A173226-","G173227-","A173228-","A173229-","G173230-","A173231-","T173232-","G173233-","T173234-","T173235-","A173236-","G173237-","A173238-","A173239-","A173240-","A173241-","A173242-","A173243-","T173244-","G173245-","A173246-","T173247-","G173248-","C173249-","T173250-","G173251-","G173252-","T173253-","T173254-","A173255-","T173256-","T173257-","A173258-","T173259-","A173260-","C173261-","A173262-","T173263-","G173264-","T173265-","G173266-","T173267-","T173268-","T173269-","T173270-","A173271-","G173272-","A173273-","A173274-","T173275-","A173276-","T173277-","A173278-","T173279-","A173280-","T173281-","A173282-","T173283-","A173284-","T173285-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","G173318-","G173319-","G173320-","C173321-","A173322-","A173323-","A173324-","A173325-","C173326-","A173327-","T173328-","A173329-","T173330-","A173331-","A173332-","C173333-","G173334-","T173335-","A173336-","A173337-","C173338-","C173339-","A173340-","G173341-","A173342-","A173343-","T173344-","T173345-","A173346-","T173347-","A173348-","A173349-","A173350-","A173351-","T173352-","T173353-","A173354-","G173355-","A173356-","G173357-","G173358-","T173359-","A173360-","C173361-","G173362-","G173363-","G173364-","A173365-","T173366-","A173367-","G173368-","A173369-","A173370-","T173371-","A173372-","A173373-","T173374-","A173375-","C173376-","C173377-","T173378-","C173379-","C173380-","T173381-","A173382-","C173383-","T173384-","A173385-","T173386-","G173387-","A173388-","A173389-","A173390-","T173391-","T173392-","A173393-","C173394-","C173395-","A173396-","G173397-","A173398-","A173399-","G173400-","G173401-","A173402-","G173403-","T173404-","A173405-","G173406-","T173407-","A173408-","A173409-","C173410-","T173411-","T173412-","C173413-","A173414-","A173415-","T173416-","A173417-","G173418-","G173419-","T173420-","A173421-","G173422-","T173423-","A173424-","A173425-","T173426-","T173427-","T173428-","G173429-","A173430-","C173431-","T173432-","A173433-","T173434-","T173435-","G173436-","C173437-","A173438-","T173439-","G173440-","T173441-","A173442-","G173443-","A173444-","G173445-","T173446-","A173447-","T173448-","C173449-","G173450-","T173451-","T173452-","G173453-","A173454-","G173455-","A173456-","C173457-","T173458-","T173459-","C173460-","C173461-","C173462-","A173463-","C173464-","A173465-","A173466-","C173467-","G173468-","G173469-","A173470-","C173471-","A173472-","C173473-","C173474-","G173475-","A173476-","C173477-","G173478-","T173479-","C173480-","T173481-","T173482-","T173483-","T173484-","G173485-","G173486-","A173487-","T173488-","A173489-","A173490-","G173491-","T173492-","A173493-","A173494-","T173495-","G173496-","G173497-","T173498-","A173499-","T173500-","A173501-","T173502-","G173503-","T173504-","A173505-","T173506-","T173507-","A173508-","C173509-","G173510-","A173511-","A173512-","G173513-","A173514-","A173515-","G173516-","A173517-","A173518-","G173519-","A173520-","C173521-","G173522-","A173523-","G173524-","G173525-","A173526-","C173527-","G173528-","G173529-","A173530-","G173531-","A173532-","C173533-","G173534-","G173535-","T173536-","A173537-","G173538-","A173539-","A173540-","T173541-","A173542-","A173543-","G173544-","T173545-","G173546-","T173547-","A173548-","G173549-","C173550-","A173551-","A173552-","A173553-","T173554-","A173555-","A173556-","A173557-","A173558-","T173559-","C173560-","T173561-","A173562-","T173563-","A173564-","T173565-","G173566-","A173567-","C173568-","C173569-","G173570-","A173571-","T173572-","A173573-","A173574-","G173575-","A173576-","G173577-","A173578-","C173579-","G173580-","T173581-","G173582-","T173583-","T173584-","A173585-","T173586-","T173587-","A173588-","C173589-","A173590-","T173591-","C173592-","C173593-","T173594-","G173595-","G173596-","T173597-","T173598-","A173599-","A173600-","A173601-","C173602-","A173603-","T173604-","T173605-","A173606-","A173607-","T173608-","C173609-","C173610-","T173611-","G173612-","T173613-","C173614-","A173615-","A173616-","G173617-","G173618-","A173619-","A173620-","G173621-","A173622-","A173623-","G173624-","A173625-","T173626-","G173627-","C173628-","T173629-","A173630-","C173631-","A173632-","A173633-","C173634-","G173635-","T173636-","T173637-","T173638-","A173639-","C173640-","G173641-","T173642-","G173643-","T173644-","A173645-","T173646-","G173647-","G173648-","C173649-","G173650-","T173651-","T173652-","T173653-","A173654-","C173655-","T173656-","A173657-","T173658-","T173659-","C173660-","C173661-","T173662-","A173663-","G173664-","C173665-","A173666-","T173667-","C173668-","A173669-","G173670-","C173671-","A173672-","A173673-","A173674-","A173675-","C173676-","A173677-","G173678-","T173679-","T173680-","A173681-","C173682-","T173683-","G173684-","T173685-","T173686-","A173687-","G173688-","T173689-","A173690-","A173691-","A173692-","C173693-","G173694-","T173695-","G173696-","A173697-","A173698-","T173699-","G173700-","T173701-","A173702-","T173703-","G173704-","T173705-","T173706-","G173707-","T173708-","T173709-","A173710-","C173711-","A173712-","T173713-","T173714-","T173715-","C173716-","C173717-","A173718-","T173719-","A173720-","T173721-","C173722-","A173723-","A173724-","T173725-","T173726-","G173727-","A173728-","G173729-","T173730-","T173731-","T173732-","A173733-","T173734-","A173735-","A173736-","G173737-","A173738-","A173739-","T173740-","T173741-","T173742-","T173743-","T173744-","T173745-","A173746-","T173747-","A173748-","C173749-","A173750-","T173751-","T173752-","A173753-","T173754-","C173755-","T173756-","T173757-","C173758-","C173759-","A173760-","A173761-","C173762-","A173763-","A173764-","A173765-","C173766-","A173767-","A173768-","T173769-","T173770-","G173771-","A173772-","C173773-","G173774-","A173775-","A173776-","C173777-","G173778-","T173779-","A173780-","T173781-","T173782-","G173783-","C173784-","T173785-","A173786-","T173787-","G173788-","A173789-","T173790-","T173791-","A173792-","A173793-","C173794-","T173795-","C173796-","C173797-","C173798-","A173799-","C173800-","A173801-","A173802-","T173803-","A173804-","C173805-","T173806-","A173807-","T173808-","A173809-","T173810-","A173811-","T173812-","A173813-","T173814-","T173815-","A173816-","T173817-","T173818-","A173819-","A173820-","T173821-","C173822-","A173823-","T173824-","T173825-","A173826-","A173827-","C173828-","T173829-","T173830-","G173831-","C173832-","A173833-","G173834-","A173835-","C173836-","T173837-","A173838-","T173839-","A173840-","C173841-","C173842-","T173843-","A173844-","G173845-","T173846-","A173847-","G173848-","T173849-","G173850-","C173851-","T173852-","A173853-","T173854-","T173855-","T173856-","T173857-","G173858-","A173859-","C173860-","A173861-","T173862-","A173863-","C173864-","T173865-","C173866-","A173867-","T173868-","G173869-","T173870-","T173871-","C173872-","T173873-","T173874-","G173875-","T173876-","G173877-","T173878-","A173879-","A173880-","T173881-","C173882-","G173883-","C173884-","A173885-","G173886-","T173887-","A173888-","T173889-","C173890-","T173891-","A173892-","T173893-","A173894-","T173895-","T173896-","A173897-","T173898-","T173899-","A173900-","A173901-","A173902-","G173903-","T173904-","A173905-","C173906-","G173907-","T173908-","A173909-","A173910-","A173911-","T173912-","C173913-","T173914-","A173915-","G173916-","C173917-","T173918-","A173919-","T173920-","A173921-","G173922-","T173923-","T173924-","T173925-","T173926-","A173927-","T173928-","T173929-","A173930-","T173931-","T173932-","T173933-","A173934-","A173935-","T173936-","T173937-","T173938-","T173939-","A173940-","G173941-","A173942-","T173943-","A173944-","A173945-","T173946-","A173947-","T173948-","A173949-","C173950-","T173951-","G173952-","T173953-","C173954-","T173955-","C173956-","C173957-","G173958-","T173959-","A173960-","T173961-","T173962-","T173963-","T173964-","T173965-","A173966-","A173967-","A173968-","A173969-","A173970-","A173971-","T173972-","T173973-","A173974-","C173975-","C173976-","A173977-","C173978-","A173979-","T173980-","C173981-","C173982-","T173983-","T173984-","T173985-","A173986-","T173987-","T173988-","A173989-","A173990-","A173991-","T173992-","C173993-","A173994-","T173995-","G173996-","A173997-","A173998-","T173999-","G174000-","G174001-","G174002-","A174003-","A174004-","T174005-","T174006-","T174007-","C174008-","T174009-","G174010-","T174011-","G174012-","T174013-","C174014-","A174015-","T174016-","C174017-","G174018-","T174019-","T174020-","A174021-","G174022-","T174023-","A174024-","T174025-","A174026-","T174027-","T174028-","G174029-","T174030-","G174031-","A174032-","A174033-","C174034-","A174035-","A174036-","C174037-","A174038-","A174039-","G174040-","A174041-","G174042-","C174043-","A174044-","G174045-","A174046-","T174047-","A174048-","T174049-","C174050-","T174051-","A174052-","T174053-","A174054-","G174055-","G174056-","A174057-","A174058-","A174059-","G174060-","G174061-","G174062-","T174063-","G174064-","G174065-","A174066-","A174067-","T174068-","G174069-","C174070-","G174071-","A174072-","T174073-","A174074-","C174075-","A174076-","T174077-","T174078-","G174079-","A174080-","T174081-","C174082-","T174083-","A174084-","T174085-","G174086-","T174087-","A174088-","G174089-","T174090-","T174091-","T174092-","T174093-","A174094-","A174095-","A174096-","A174097-","C174098-","A174099-","T174100-","A174101-","C174102-","G174103-","C174104-","G174105-","A174106-","A174107-","C174108-","T174109-","T174110-","T174111-","G174112-","A174113-","A174114-","G174115-","A174116-","A174117-","T174118-","T174119-","T174120-","A174121-","T174122-","A174123-","T174124-","A174125-","A174126-","A174127-","T174128-","C174129-","A174130-","T174131-","C174132-","T174133-","C174134-","A174135-","C174136-","G174137-","A174138-","G174139-","A174140-","T174141-","A174142-","T174143-","T174144-","G174145-","C174146-","T174147-","C174148-","T174149-","C174150-","T174151-","G174152-","T174153-","C174154-","A174155-","T174156-","A174157-","T174158-","T174159-","C174160-","A174161-","T174162-","A174163-","C174164-","A174165-","C174166-","C174167-","T174168-","G174169-","T174170-","A174171-","T174172-","A174173-","A174174-","A174175-","C174176-","T174177-","T174178-","T174179-","C174180-","T174181-","A174182-","G174183-","A174184-","C174185-","A174186-","T174187-","C174188-","T174189-","T174190-","A174191-","C174192-","A174193-","A174194-","T174195-","G174196-","T174197-","G174198-","T174199-","T174200-","A174201-","T174202-","T174203-","T174204-","T174205-","A174206-","T174207-","G174208-","A174209-","T174210-","C174211-","A174212-","T174213-","A174214-","T174215-","T174216-","T174217-","A174218-","C174219-","A174220-","T174221-","A174222-","T174223-","T174224-","T174225-","A174226-","C174227-","T174228-","G174229-","G174230-","T174231-","A174232-","T174233-","A174234-","T174235-","C174236-","A174237-","A174238-","A174239-","G174240-","A174241-","T174242-","G174243-","T174244-","T174245-","A174246-","G174247-","A174248-","T174249-","T174250-","A174251-","G174252-","T174253-","T174254-","A174255-","A174256-","T174257-","G174258-","G174259-","G174260-","A174261-","A174262-","T174263-","C174264-","G174265-","T174266-","C174267-","T174268-","A174269-","T174270-","A174271-","A174272-","T174273-","A174274-","A174275-","T174276-","G174277-","A174278-","A174279-","T174280-","A174281-","T174282-","T174283-","A174284-","A174285-","A174286-","C174287-","A174288-","A174289-","T174290-","T174291-","A174292-","T174293-","A174294-","G174295-","G174296-","A174297-","G174298-","G174299-","A174300-","G174301-","T174302-","T174303-","T174304-","A174305-","T174306-","A174307-","C174308-","C174309-","T174310-","A174311-","C174312-","A174313-","A174314-","A174315-","A174316-","A174317-","C174318-","A174319-","T174320-","C174321-","A174322-","T174323-","A174324-","A174325-","A174326-","A174327-","A174328-","T174329-","G174330-","A174331-","G174332-","T174333-","C174334-","A174335-","T174336-","C174337-","G174338-","T174339-","C174340-","C174341-","G174342-","A174343-","T174344-","T174345-","T174346-","A174347-","T174348-","G174349-","T174350-","T174351-","T174352-","T174353-","A174354-","A174355-","A174356-","T174357-","A174358-","T174359-","A174360-","C174361-","T174362-","A174363-","A174364-","C174365-","A174366-","T174367-","T174368-","A174369-","C174370-","T174371-","A174372-","C174373-","C174374-","T174375-","T174376-","C174377-","A174378-","G174379-","A174380-","A174381-","A174382-","T174383-","T174384-","A174385-","T174386-","A174387-","T174388-","A174389-","C174390-","G174391-","A174392-","A174393-","A174394-","T174395-","A174396-","T174397-","T174398-","A174399-","T174400-","A174401-","C174402-","A174403-","T174404-","G174405-","C174406-","T174407-","G174408-","A174409-","C174410-","A174411-","A174412-","T174413-","T174414-","A174415-","A174416-","C174417-","G174418-","A174419-","T174420-","C174421-","T174422-","T174423-","T174424-","A174425-","T174426-","A174427-","A174428-","T174429-","A174430-","T174431-","A174432-","T174433-","A174434-","G174435-","T174436-","A174437-","T174438-","C174439-","C174440-","A174441-","C174442-","C174443-","T174444-","A174445-","C174446-","C174447-","A174448-","A174449-","A174450-","G174451-","T174452-","A174453-","T174454-","A174455-","A174456-","T174457-","T174458-","G174459-","T174460-","A174461-","T174462-","T174463-","T174464-","T174465-","T174466-","C174467-","T174468-","C174469-","A174470-","T174471-","G174472-","T174473-","G174474-","A174475-","T174476-","G174477-","T174478-","G174479-","T174480-","G174481-","T174482-","A174483-","A174484-","A174485-","A174486-","A174487-","A174488-","C174489-","T174490-","G174491-","A174492-","T174493-","A174494-","T174495-","T174496-","A174497-","T174498-","A174499-","T174500-","A174501-","A174502-","T174503-","T174504-","A174505-","T174506-","C174507-","T174508-","T174509-","A174510-","G174511-","T174512-","A174513-","C174514-","C174515-","T174516-","A174517-","T174518-","G174519-","A174520-","T174521-","G174522-","A174523-","A174524-","G174525-","A174526-","T174527-","G174528-","A174529-","A174530-","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","G174537-","A174538-","T174539-","G174540-","A174541-","A174542-","G174543-","A174544-","T174545-","G174546-","A174547-","T174548-","G174549-","G174550-","T174551-","C174552-","C174553-","G174554-","T174555-","A174556-","T174557-","A174558-","T174559-","A174560-","T174561-","T174562-","T174563-","T174564-","G174565-","T174566-","A174567-","T174568-","C174569-","A174570-","T174571-","T174572-","A174573-","T174574-","C174575-","G174576-","T174577-","T174578-","A174579-","T174580-","T174581-","G174582-","C174583-","T174584-","A174585-","T174586-","T174587-","C174588-","C174589-","A174590-","T174591-","A174592-","G174593-","T174594-","T174595-","A174596-","C174597-","G174598-","C174599-","C174600-","A174601-","T174602-","A174603-","G174604-","A174605-","C174606-","A174607-","T174608-","C174609-","G174610-","A174611-","A174612-","A174613-","A174614-","T174615-","G174616-","A174617-","A174618-","A174619-","T174620-","C174621-","A174622-","C174623-","C174624-","G174625-","A174626-","A174627-","T174628-","T174629-","C174630-","T174631-","T174632-","C174633-","A174634-","A174635-","T174636-","A174637-","A174638-","A174639-","A174640-","T174641-","G174642-","A174643-","G174644-","A174645-","G174646-","A174647-","T174648-","A174649-","C174650-","T174651-","C174652-","T174653-","A174654-","C174655-","C174656-","A174657-","G174658-","C174659-","T174660-","A174661-","A174662-","A174663-","G174664-","A174665-","C174666-","T174667-","C174668-","T174669-","A174670-","A174671-","A174672-","T174673-","G174674-","G174675-","T174676-","T174677-","G174678-","A174679-","A174680-","T174681-","C174682-","C174683-","A174684-","G174685-","T174686-","A174687-","T174688-","G174689-","T174690-","A174691-","T174692-","G174693-","T174694-","T174695-","T174696-","G174697-","G174698-","A174699-","G174700-","G174701-","C174702-","A174703-","C174704-","A174705-","A174706-","T174707-","G174708-","A174709-","A174710-","T174711-","G174712-","A174713-","T174714-","A174715-","T174716-","G174717-","G174718-","C174719-","C174720-","G174721-","C174722-","T174723-","C174724-","T174725-","A174726-","G174727-","G174728-","A174729-","G174730-","A174731-","G174732-","C174733-","C174734-","A174735-","T174736-","T174737-","C174738-","A174739-","G174740-","T174741-","G174742-","C174743-","A174744-","A174745-","A174746-","G174747-","T174748-","G174749-","T174750-","C174751-","C174752-","T174753-","C174754-","C174755-","T174756-","A174757-","T174758-","T174759-","G174760-","A174761-","A174762-","G174763-","A174764-","C174765-","A174766-","G174767-","T174768-","C174769-","T174770-","T174771-","T174772-","T174773-","A174774-","T174775-","C174776-","G174777-","C174778-","A174779-","T174780-","A174781-","G174782-","A174783-","T174784-","A174785-","T174786-","A174787-","A174788-","A174789-","G174790-","A174791-","C174792-","T174793-","A174794-","T174795-","G174796-","T174797-","G174798-","G174799-","T174800-","T174801-","A174802-","A174803-","A174804-","T174805-","G174806-","G174807-","G174808-","A174809-","A174810-","A174811-","G174812-","G174813-","C174814-","T174815-","A174816-","G174817-","A174818-","A174819-","A174820-","A174821-","G174822-","A174823-","A174824-","T174825-","A174826-","G174827-","A174828-","C174829-","G174830-","G174831-","C174832-","G174833-","A174834-","C174835-","A174836-","G174837-","G174838-","T174839-","T174840-","T174841-","C174842-","T174843-","A174844-","A174845-","T174846-","A174847-","A174848-","A174849-","C174850-","G174851-","T174852-","G174853-","T174854-","T174855-","A174856-","A174857-","A174858-","C174859-","A174860-","T174861-","G174862-","G174863-","T174864-","G174865-","A174866-","T174867-","T174868-","T174869-","A174870-","T174871-","G174872-","G174873-","A174874-","T174875-","A174876-","G174877-","C174878-","C174879-","A174880-","A174881-","C174882-","T174883-","A174884-","T174885-","A174886-","C174887-","A174888-","T174889-","C174890-","T174891-","A174892-","A174893-","A174894-","T174895-","T174896-","C174897-","A174898-","G174899-","T174900-","A174901-","A174902-","C174903-","C174904-","G174905-","T174906-","A174907-","G174908-","G174909-","T174910-","A174911-","T174912-","T174913-","T174914-","A174915-","T174916-","G174917-","T174918-","A174919-","C174920-","C174921-","G174922-","T174923-","A174924-","A174925-","C174926-","C174927-","A174928-","C174929-","A174930-","A174931-","A174932-","G174933-","A174934-","A174935-","T174936-","G174937-","G174938-","T174939-","G174940-","A174941-","C174942-","T174943-","G174944-","T174945-","G174946-","T174947-","T174948-","C174949-","A174950-","G174951-","G174952-","G174953-","T174954-","G174955-","T174956-","A174957-","G174958-","T174959-","T174960-","A174961-","G174962-","A174963-","T174964-","C174965-","T174966-","C174967-","A174968-","T174969-","G174970-","T174971-","G174972-","T174973-","G174974-","G174975-","A174976-","A174977-","A174978-","C174979-","C174980-","T174981-","T174982-","C174983-","T174984-","T174985-","C174986-","A174987-","T174988-","G174989-","C174990-","A174991-","T174992-","T174993-","C174994-","C174995-","A174996-","A174997-","A174998-","A174999-","A175000-","C175001-","A175002-","T175003-","A175004-","T175005-","G175006-","A175007-","A175008-","C175009-","T175010-","A175011-","G175012-","G175013-","T175014-","A175015-","C175016-","T175017-","T175018-","A175019-","T175020-","G175021-","A175022-","T175023-","A175024-","A175025-","G175026-","T175027-","A175028-","T175029-","G175030-","G175031-","C175032-","A175033-","T175034-","A175035-","G175036-","A175037-","C175038-","T175039-","T175040-","A175041-","T175042-","A175043-","C175044-","T175045-","G175046-","T175047-","G175048-","G175049-","A175050-","A175051-","T175052-","T175053-","C175054-","T175055-","T175056-","T175057-","A175058-","T175059-","G175060-","C175061-","G175062-","A175063-","A175064-","C175065-","C175066-","A175067-","T175068-","T175069-","A175070-","T175071-","A175072-","A175073-","T175074-","A175075-","A175076-","T175077-","A175078-","T175079-","A175080-","A175081-","C175082-","T175083-","T175084-","G175085-","G175086-","T175087-","A175088-","T175089-","A175090-","A175091-","A175092-","G175093-","A175094-","T175095-","A175096-","A175097-","T175098-","A175099-","A175100-","G175101-","G175102-","A175103-","A175104-","A175105-","T175106-","T175107-","A175108-","A175109-","T175110-","A175111-","T175112-","C175113-","G175114-","A175115-","C175116-","G175117-","A175118-","T175119-","T175120-","T175121-","T175122-","A175123-","A175124-","G175125-","T175126-","A175127-","T175128-","T175129-","C175130-","A175131-","C175132-","A175133-","A175134-","G175135-","C175136-","G175137-","G175138-","G175139-","A175140-","A175141-","A175142-","G175143-","G175144-","A175145-","A175146-","T175147-","T175148-","A175149-","A175150-","T175151-","T175152-","A175153-","T175154-","T175155-","C175156-","A175157-","T175158-","A175159-","A175160-","T175161-","C175162-","C175163-","A175164-","G175165-","A175166-","G175167-","T175168-","T175169-","A175170-","G175171-","A175172-","A175173-","G175174-","A175175-","T175176-","A175177-","G175178-","T175179-","G175180-","G175181-","A175182-","A175183-","G175184-","A175185-","T175186-","A175187-","C175188-","G175189-","A175190-","C175191-","T175192-","G175193-","T175194-","T175195-","A175196-","C175197-","G175198-","T175199-","T175200-","C175201-","A175202-","T175203-","T175204-","A175205-","C175206-","G175207-","A175208-","C175209-","G175210-","A175211-","C175212-","G175213-","T175214-","T175215-","A175216-","G175217-","A175218-","A175219-","T175220-","C175221-","A175222-","A175223-","G175224-","A175225-","A175226-","T175227-","G175228-","A175229-","T175230-","A175231-","T175232-","C175233-","G175234-","T175235-","A175236-","G175237-","T175238-","A175239-","T175240-","C175241-","A175242-","A175243-","G175244-","A175245-","T175246-","G175247-","T175248-","A175249-","A175250-","A175251-","A175252-","T175253-","A175254-","C175255-","T175256-","T175257-","A175258-","C175259-","G175260-","G175261-","T175262-","T175263-","A175264-","T175265-","A175266-","C175267-","C175268-","G175269-","T175270-","C175271-","A175272-","C175273-","A175274-","A175275-","G175276-","A175277-","C175278-","C175279-","A175280-","C175281-","A175282-","G175283-","G175284-","T175285-","T175286-","T175287-","A175288-","A175289-","A175290-","C175291-","T175292-","A175293-","A175294-","T175295-","A175296-","C175297-","T175298-","A175299-","G175300-","A175301-","T175302-","C175303-","C175304-","G175305-","A175306-","A175307-","A175308-","A175309-","T175310-","C175311-","A175312-","A175313-","C175314-","G175315-","T175316-","A175317-","A175318-","C175319-","G175320-","A175321-","T175322-","A175323-","G175324-","G175325-","A175326-","G175327-","A175328-","A175329-","C175330-","C175331-","T175332-","G175333-","C175334-","C175335-","A175336-","A175337-","T175338-","A175339-","T175340-","A175341-","A175342-","C175343-","A175344-","T175345-","G175346-","C175347-","A175348-","G175349-","T175350-","G175351-","C175352-","T175353-","G175354-","T175355-","G175356-","T175357-","C175358-","A175359-","A175360-","C175361-","G175362-","T175363-","C175364-","A175365-","T175366-","T175367-","A175368-","T175369-","T175370-","T175371-","G175372-","T175373-","C175374-","G175375-","A175376-","C175377-","G175378-","A175379-","T175380-","G175381-","T175382-","A175383-","C175384-","T175385-","G175386-","A175387-","T175388-","T175389-","G175390-","A175391-","A175392-","T175393-","G175394-","G175395-","G175396-","A175397-","A175398-","A175399-","A175400-","T175401-","C175402-","C175403-","A175404-","T175405-","C175406-","C175407-","G175408-","G175409-","A175410-","T175411-","G175412-","G175413-","A175414-","T175415-","T175416-","A175417-","T175418-","A175419-","G175420-","G175421-","A175422-","T175423-","T175424-","A175425-","G175426-","A175427-","T175428-","T175429-","T175430-","T175431-","G175432-","G175433-","T175434-","G175435-","T175436-","A175437-","T175438-","A175439-","C175440-","T175441-","C175442-","T175443-","A175444-","T175445-","T175446-","T175447-","T175448-","A175449-","A175450-","C175451-","T175452-","A175453-","G175454-","T175455-","A175456-","G175457-","A175458-","G175459-","G175460-","C175461-","G175462-","G175463-","T175464-","A175465-","T175466-","C175467-","A175468-","C175469-","C175470-","G175471-","A175472-","G175473-","G175474-","C175475-","G175476-","A175477-","C175478-","T175479-","T175480-","T175481-","G175482-","T175483-","A175484-","T175485-","T175486-","T175487-","T175488-","G175489-","A175490-","A175491-","A175492-","A175493-","T175494-","G175495-","T175496-","T175497-","A175498-","C175499-","T175500-","G175501-","A175502-","A175503-","G175504-","A175505-","A175506-","T175507-","A175508-","T175509-","A175510-","T175511-","A175512-","G175513-","G175514-","C175515-","A175516-","A175517-","T175518-","A175519-","C175520-","A175521-","T175522-","A175523-","T175524-","A175525-","C175526-","A175527-","T175528-","G175529-","T175530-","C175531-","G175532-","T175533-","G175534-","G175535-","A175536-","C175537-","A175538-","C175539-","A175540-","A175541-","C175542-","T175543-","A175544-","T175545-","T175546-","A175547-","T175548-","T175549-","T175550-","T175551-","G175552-","A175553-","T175554-","A175555-","A175556-","A175557-","A175558-","C175559-","T175560-","C175561-","T175562-","T175563-","A175564-","C175565-","A175566-","A175567-","C175568-","T175569-","A175570-","C175571-","A175572-","G175573-","T175574-","A175575-","G175576-","T175577-","A175578-","T175579-","T175580-","G175581-","G175582-","A175583-","G175584-","T175585-","A175586-","A175587-","A175588-","T175589-","A175590-","C175591-","A175592-","C175593-","A175594-","A175595-","T175596-","G175597-","C175598-","A175599-","T175600-","T175601-","T175602-","T175603-","T175604-","A175605-","T175606-","A175607-","T175608-","A175609-","C175610-","A175611-","T175612-","T175613-","A175614-","C175615-","T175616-","G175617-","A175618-","A175619-","T175620-","T175621-","A175622-","T175623-","T175624-","A175625-","T175626-","T175627-","A175628-","T175629-","T175630-","A175631-","A175632-","T175633-","T175634-","A175635-","T175636-","A175637-","T175638-","C175639-","G175640-","T175641-","A175642-","T175643-","T175644-","T175645-","G175646-","T175647-","G175648-","C175649-","T175650-","A175651-","T175652-","A175653-","G175654-","A175655-","A175656-","T175657-","G175658-","G175659-","A175660-","T175661-","G175662-","A175663-","A175664-","G175665-","A175666-","T175667-","A175668-","C175669-","G175670-","C175671-","G175672-","A175673-","C175674-","T175675-","A175676-","T175677-","C175678-","T175679-","A175680-","G175681-","G175682-","T175683-","A175684-","T175685-","T175686-","T175687-","G175688-","T175689-","A175690-","T175691-","C175692-","T175693-","C175694-","A175695-","C175696-","C175697-","G175698-","A175699-","T175700-","A175701-","G175702-","A175703-","G175704-","A175705-","A175706-","C175707-","A175708-","T175709-","A175710-","T175711-","A175712-","A175713-","A175714-","T175715-","G175716-","T175717-","A175718-","G175719-","A175720-","C175721-","T175722-","C175723-","T175724-","A175725-","T175726-","T175727-","A175728-","A175729-","A175730-","C175731-","A175732-","G175733-","T175734-","T175735-","G175736-","T175737-","G175738-","T175739-","A175740-","A175741-","A175742-","A175743-","T175744-","A175745-","T175746-","C175747-","A175748-","G175749-","A175750-","T175751-","C175752-","C175753-","T175754-","A175755-","A175756-","T175757-","G175758-","C175759-","A175760-","T175761-","G175762-","T175763-","T175764-","A175765-","T175766-","A175767-","G175768-","A175769-","T175770-","G175771-","T175772-","G175773-","G175774-","A175775-","T175776-","G175777-","T175778-","A175779-","C175780-","G175781-","G175782-","C175783-","T175784-","T175785-","T175786-","A175787-","C175788-","A175789-","T175790-","G175791-","A175792-","G175793-","T175794-","A175795-","C175796-","T175797-","T175798-","T175799-","T175800-","A175801-","T175802-","A175803-","A175804-","T175805-","T175806-","A175807-","T175808-","A175809-","G175810-","A175811-","T175812-","C175813-","A175814-","G175815-","T175816-","C175817-","A175818-","A175819-","C175820-","G175821-","G175822-","A175823-","A175824-","A175825-","A175826-","T175827-","A175828-","C175829-","A175830-","A175831-","G175832-","T175833-","A175834-","T175835-","A175836-","G175837-","A175838-","T175839-","A175840-","C175841-","A175842-","A175843-","C175844-","G175845-","G175846-","T175847-","T175848-","A175849-","C175850-","T175851-","A175852-","T175853-","C175854-","A175855-","A175856-","T175857-","A175858-","T175859-","T175860-","A175861-","T175862-","T175863-","C175864-","A175865-","T175866-","C175867-","T175868-","A175869-","G175870-","C175871-","G175872-","A175873-","T175874-","T175875-","A175876-","T175877-","G175878-","A175879-","A175880-","A175881-","A175882-","T175883-","T175884-","A175885-","T175886-","A175887-","A175888-","T175889-","G175890-","A175891-","A175892-","T175893-","A175894-","T175895-","T175896-","A175897-","T175898-","T175899-","A175900-","T175901-","G175902-","A175903-","T175904-","G175905-","A175906-","T175907-","T175908-","A175909-","T175910-","G175911-","A175912-","T175913-","A175914-","G175915-","A175916-","A175917-","C175918-","T175919-","G175920-","G175921-","T175922-","A175923-","T175924-","G175925-","A175926-","A175927-","C175928-","A175929-","G175930-","T175931-","G175932-","A175933-","G175934-","A175935-","G175936-","T175937-","G175938-","A175939-","T175940-","A175941-","A175942-","T175943-","A175944-","T175945-","A175946-","T175947-","C175948-","A175949-","A175950-","T175951-","C175952-","A175953-","A175954-","A175955-","A175956-","C175957-","A175958-","G175959-","A175960-","A175961-","T175962-","A175963-","C175964-","G175965-","A175966-","G175967-","A175968-","A175969-","T175970-","G175971-","A175972-","A175973-","T175974-","A175975-","T175976-","G175977-","A175978-","A175979-","T175980-","T175981-","C175982-","T175983-","A175984-","T175985-","G175986-","A175987-","T175988-","G175989-","A175990-","A175991-","A175992-","C175993-","A175994-","C175995-","A175996-","A175997-","G175998-","A175999-","T176000-","C176001-","A176002-","A176003-","A176004-","G176005-","T176006-","A176007-","C176008-","A176009-","C176010-","A176011-","A176012-","C176013-","T176014-","A176015-","G176016-","T176017-","A176018-","G176019-","A176020-","T176021-","T176022-","A176023-","C176024-","G176025-","A176026-","C176027-","A176028-","T176029-","T176030-","A176031-","A176032-","A176033-","C176034-","T176035-","C176036-","A176037-","A176038-","A176039-","A176040-","C176041-","C176042-","A176043-","A176044-","T176045-","G176046-","A176047-","G176048-","G176049-","A176050-","T176051-","G176052-","A176053-","T176054-","T176055-","T176056-","T176057-","G176058-","T176059-","T176060-","G176061-","A176062-","T176063-","G176064-","A176065-","A176066-","T176067-","T176068-","C176069-","T176070-","A176071-","T176072-","G176073-","G176074-","T176075-","T176076-","A176077-","T176078-","G176079-","A176080-","T176081-","A176082-","G176083-","A176084-","T176085-","C176086-","A176087-","G176088-","T176089-","G176090-","G176091-","G176092-","T176093-","G176094-","T176095-","C176096-","C176097-","A176098-","T176099-","G176100-","A176101-","T176102-","T176103-","A176104-","T176105-","A176106-","T176107-","A176108-","G176109-","A176110-","T176111-","G176112-","T176113-","A176114-","T176115-","C176116-","A176117-","A176118-","T176119-","T176120-","A176121-","A176122-","T176123-","A176124-","A176125-","A176126-","G176127-","T176128-","A176129-","G176130-","T176131-","A176132-","T176133-","A176134-","T176135-","G176136-","G176137-","A176138-","A176139-","G176140-","A176141-","G176142-","A176143-","G176144-","T176145-","C176146-","T176147-","C176148-","A176149-","C176150-","G176151-","T176152-","A176153-","A176154-","G176155-","A176156-","T176157-","G176158-","G176159-","T176160-","G176161-","G176162-","G176163-","A176164-","T176165-","A176166-","T176167-","A176168-","T176169-","G176170-","G176171-","C176172-","A176173-","A176174-","G176175-","A176176-","A176177-","C176178-","A176179-","T176180-","A176181-","A176182-","T176183-","G176184-","A176185-","T176186-","G176187-","G176188-","C176189-","G176190-","T176191-","A176192-","T176193-","A176194-","C176195-","A176196-","G176197-","T176198-","A176199-","T176200-","A176201-","G176202-","G176203-","A176204-","A176205-","A176206-","G176207-","G176208-","A176209-","G176210-","T176211-","G176212-","C176213-","A176214-","T176215-","A176216-","G176217-","A176218-","T176219-","A176220-","A176221-","T176222-","A176223-","T176224-","A176225-","T176226-","A176227-","C176228-","G176229-","A176230-","A176231-","G176232-","A176233-","C176234-","A176235-","G176236-","A176237-","C176238-","A176239-","T176240-","A176241-","C176242-","C176243-","G176244-","T176245-","A176246-","G176247-","A176248-","C176249-","G176250-","A176251-","A176252-","T176253-","T176254-","C176255-","T176256-","A176257-","C176258-","A176259-","A176260-","G176261-","A176262-","T176263-","A176264-","G176265-","A176266-","C176267-","A176268-","G176269-","C176270-","G176271-","T176272-","A176273-","T176274-","C176275-","A176276-","G176277-","A176278-","T176279-","G176280-","T176281-","A176282-","G176283-","A176284-","T176285-","G176286-","A176287-","C176288-","G176289-","C176290-","A176291-","G176292-","A176293-","A176294-","C176295-","A176296-","T176297-","A176298-","T176299-","A176300-","T176301-","C176302-","T176303-","C176304-","A176305-","G176306-","A176307-","T176308-","A176309-","A176310-","C176311-","T176312-","A176313-","A176314-","T176315-","G176316-","A176317-","T176318-","G176319-","T176320-","A176321-","T176322-","C176323-","T176324-","A176325-","C176326-","A176327-","C176328-","A176329-","A176330-","A176331-","C176332-","A176333-","T176334-","G176335-","G176336-","G176337-","A176338-","A176339-","A176340-","A176341-","G176342-","A176343-","A176344-","A176345-","T176346-","C176347-","A176348-","G176349-","A176350-","G176351-","T176352-","T176353-","A176354-","G176355-","A176356-","T176357-","A176358-","G176359-","A176360-","T176361-","A176362-","C176363-","A176364-","T176365-","G176366-","G176367-","A176368-","A176369-","A176370-","T176371-","G176372-","T176373-","A176374-","T176375-","C176376-","C176377-","T176378-","C176379-","G176380-","T176381-","C176382-","A176383-","T176384-","A176385-","G176386-","A176387-","T176388-","A176389-","T176390-","G176391-","G176392-","T176393-","A176394-","A176395-","G176396-","C176397-","A176398-","T176399-","T176400-","C176401-","T176402-","G176403-","T176404-","C176405-","T176406-","T176407-","T176408-","A176409-","A176410-","G176411-","G176412-","G176413-","A176414-","T176415-","T176416-","T176417-","T176418-","C176419-","T176420-","G176421-","A176422-","C176423-","A176424-","A176425-","A176426-","G176427-","T176428-","T176429-","A176430-","G176431-","A176432-","A176433-","A176434-","A176435-","A176436-","A176437-","T176438-","G176439-","A176440-","T176441-","T176442-","T176443-","A176444-","G176445-","A176446-","C176447-","A176448-","T176449-","G176450-","A176451-","A176452-","C176453-","G176454-","T176455-","G176456-","G176457-","T176458-","A176459-","A176460-","A176461-","A176462-","G176463-","A176464-","A176465-","T176466-","T176467-","A176468-","C176469-","T176470-","T176471-","T176472-","C176473-","T176474-","A176475-","A176476-","C176477-","G176478-","G176479-","T176480-","G176481-","C176482-","A176483-","T176484-","C176485-","T176486-","C176487-","T176488-","A176489-","A176490-","C176491-","A176492-","A176493-","T176494-","C176495-","A176496-","A176497-","G176498-","G176499-","A176500-","T176501-","A176502-","G176503-","C176504-","A176505-","G176506-","T176507-","A176508-","A176509-","T176510-","A176511-","A176512-","G176513-","G176514-","A176515-","T176516-","C176517-","C176518-","A176519-","A176520-","T176521-","T176522-","G176523-","C176524-","T176525-","G176526-","T176527-","T176528-","T176529-","A176530-","T176531-","T176532-","T176533-","T176534-","A176535-","G176536-","A176537-","A176538-","G176539-","A176540-","A176541-","C176542-","A176543-","A176544-","T176545-","A176546-","A176547-","T176548-","G176549-","A176550-","A176551-","T176552-","T176553-","T176554-","A176555-","G176556-","A176557-","A176558-","A176559-","T176560-","G176561-","A176562-","T176563-","T176564-","G176565-","A176566-","T176567-","A176568-","T176569-","C176570-","A176571-","T176572-","T176573-","A176574-","A176575-","C176576-","A176577-","A176578-","A176579-","C176580-","A176581-","T176582-","A176583-","C176584-","A176585-","A176586-","C176587-","T176588-","A176589-","T176590-","C176591-","T176592-","A176593-","T176594-","G176595-","A176596-","A176597-","C176598-","G176599-","C176600-","A176601-","G176602-","G176603-","T176604-","A176605-","T176606-","A176607-","T176608-","A176609-","G176610-","T176611-","A176612-","C176613-","A176614-","C176615-","T176616-","C176617-","C176618-","T176619-","A176620-","T176621-","C176622-","T176623-","A176624-","A176625-","A176626-","A176627-","A176628-","A176629-","T176630-","T176631-","A176632-","T176633-","A176634-","G176635-","A176636-","A176637-","A176638-","T176639-","T176640-","T176641-","C176642-","G176643-","A176644-","T176645-","T176646-","A176647-","T176648-","C176649-","C176650-","A176651-","T176652-","T176653-","T176654-","T176655-","T176656-","C176657-","A176658-","G176659-","A176660-","A176661-","A176662-","G176663-","T176664-","T176665-","A176666-","G176667-","T176668-","T176669-","T176670-","T176671-","G176672-","A176673-","C176674-","T176675-","A176676-","A176677-","T176678-","A176679-","A176680-","A176681-","C176682-","A176683-","T176684-","T176685-","G176686-","T176687-","C176688-","T176689-","C176690-","A176691-","A176692-","C176693-","A176694-","A176695-","T176696-","T176697-","A176698-","T176699-","T176700-","G176701-","T176702-","A176703-","A176704-","T176705-","A176706-","T176707-","A176708-","A176709-","G176710-","C176711-","G176712-","A176713-","C176714-","G176715-","G176716-","C176717-","A176718-","A176719-","A176720-","T176721-","A176722-","T176723-","G176724-","G176725-","A176726-","A176727-","C176728-","A176729-","C176730-","C176731-","A176732-","C176733-","T176734-","A176735-","C176736-","A176737-","T176738-","A176739-","T176740-","A176741-","T176742-","T176743-","A176744-","G176745-","C176746-","A176747-","T176748-","C176749-","T176750-","A176751-","A176752-","T176753-","A176754-","A176755-","A176756-","A176757-","A176758-","A176759-","A176760-","T176761-","A176762-","A176763-","T176764-","A176765-","A176766-","C176767-","T176768-","C176769-","C176770-","T176771-","A176772-","A176773-","T176774-","T176775-","A176776-","C176777-","A176778-","T176779-","G176780-","A176781-","A176782-","G176783-","T176784-","T176785-","A176786-","T176787-","T176788-","A176789-","G176790-","T176791-","G176792-","T176793-","A176794-","T176795-","A176796-","A176797-","C176798-","G176799-","G176800-","A176801-","A176802-","A176803-","T176804-","G176805-","A176806-","T176807-","A176808-","T176809-","A176810-","A176811-","A176812-","C176813-","G176814-","C176815-","A176816-","C176817-","G176818-","A176819-","G176820-","G176821-","T176822-","G176823-","A176824-","A176825-","G176826-","A176827-","T176828-","A176829-","C176830-","A176831-","C176832-","A176833-","A176834-","A176835-","T176836-","G176837-","C176838-","G176839-","A176840-","A176841-","C176842-","T176843-","C176844-","C176845-","A176846-","T176847-","T176848-","A176849-","C176850-","A176851-","C176852-","A176853-","A176854-","A176855-","T176856-","A176857-","T176858-","T176859-","T176860-","G176861-","T176862-","G176863-","T176864-","A176865-","A176866-","A176867-","T176868-","T176869-","T176870-","G176871-","T176872-","A176873-","T176874-","A176875-","T176876-","C176877-","A176878-","T176879-","A176880-","A176881-","T176882-","A176883-","T176884-","T176885-","G176886-","A176887-","A176888-","T176889-","A176890-","T176891-","G176892-","G176893-","T176894-","A176895-","T176896-","C176897-","C176898-","G176899-","A176900-","T176901-","A176902-","C176903-","T176904-","A176905-","T176906-","A176907-","A176908-","T176909-","G176910-","A176911-","A176912-","A176913-","A176914-","G176915-","A176916-","T176917-","T176918-","A176919-","T176920-","A176921-","G176922-","A176923-","C176924-","G176925-","C176926-","A176927-","T176928-","T176929-","T176930-","A176931-","T176932-","A176933-","G176934-","A176935-","G176936-","T176937-","T176938-","A176939-","G176940-","G176941-","A176942-","G176943-","C176944-","C176945-","G176946-","A176947-","T176948-","C176949-","T176950-","A176951-","A176952-","C176953-","T176954-","A176955-","T176956-","T176957-","C176958-","C176959-","A176960-","A176961-","A176962-","T176963-","G176964-","A176965-","C176966-","G176967-","A176968-","T176969-","G176970-","G176971-","A176972-","A176973-","T176974-","G176975-","A176976-","T176977-","A176978-","C176979-","C176980-","A176981-","G176982-","T176983-","A176984-","G176985-","T176986-","T176987-","T176988-","A176989-","C176990-","T176991-","G176992-","T176993-","A176994-","T176995-","A176996-","C176997-","A176998-","C176999-","T177000-","C177001-","A177002-","A177003-","A177004-","T177005-","G177006-","C177007-","C177008-","G177009-","A177010-","A177011-","T177012-","A177013-","T177014-","G177015-","G177016-","T177017-","T177018-","A177019-","T177020-","A177021-","A177022-","C177023-","A177024-","A177025-","T177026-","A177027-","T177028-","T177029-","A177030-","C177031-","T177032-","A177033-","A177034-","C177035-","A177036-","T177037-","A177038-","A177039-","A177040-","G177041-","A177042-","T177043-","A177044-","A177045-","T177046-","A177047-","C177048-","G177049-","T177050-","A177051-","A177052-","A177053-","C177054-","T177055-","A177056-","C177057-","T177058-","T177059-","A177060-","A177061-","T177062-","C177063-","T177064-","T177065-","A177066-","G177067-","T177068-","A177069-","G177070-","A177071-","C177072-","A177073-","T177074-","G177075-","C177076-","G177077-","T177078-","C177079-","A177080-","C177081-","A177082-","T177083-","A177084-","A177085-","T177086-","C177087-","T177088-","A177089-","T177090-","T177091-","T177092-","A177093-","G177094-","A177095-","G177096-","A177097-","T177098-","C177099-","G177100-","A177101-","G177102-","T177103-","C177104-","A177105-","T177106-","G177107-","C177108-","A177109-","C177110-","G177111-","A177112-","T177113-","T177114-","A177115-","T177116-","A177117-","T177118-","A177119-","A177120-","G177121-","T177122-","A177123-","A177124-","T177125-","A177126-","C177127-","A177128-","T177129-","A177130-","T177131-","A177132-","T177133-","T177134-","G177135-","A177136-","T177137-","C177138-","T177139-","T177140-","G177141-","A177142-","G177143-","T177144-","G177145-","T177146-","T177147-","T177148-","A177149-","G177150-","A177151-","T177152-","A177153-","T177154-","C177155-","A177156-","T177157-","T177158-","A177159-","G177160-","A177161-","T177162-","C177163-","A177164-","C177165-","T177166-","T177167-","G177168-","A177169-","T177170-","G177171-","G177172-","G177173-","T177174-","A177175-","C177176-","G177177-","A177178-","T177179-","A177180-","T177181-","T177182-","A177183-","A177184-","T177185-","T177186-","G177187-","T177188-","T177189-","A177190-","C177191-","T177192-","T177193-","T177194-","G177195-","A177196-","A177197-","G177198-","G177199-","A177200-","C177201-","G177202-","T177203-","A177204-","C177205-","A177206-","C177207-","C177208-","A177209-","C177210-","T177211-","T177212-","C177213-","A177214-","T177215-","T177216-","G177217-","C177218-","G177219-","C177220-","T177221-","A177222-","T177223-","A177224-","C177225-","A177226-","A177227-","T177228-","A177229-","T177230-","A177231-","A177232-","C177233-","T177234-","T177235-","C177236-","A177237-","C177238-","T177239-","C177240-","A177241-","G177242-","A177243-","T177244-","T177245-","G177246-","C177247-","T177248-","G177249-","A177250-","G177251-","T177252-","A177253-","C177254-","T177255-","T177256-","A177257-","T177258-","T177259-","A177260-","G177261-","A177262-","T177263-","C177264-","G177265-","A177266-","G177267-","G177268-","A177269-","G177270-","C177271-","T177272-","G177273-","A177274-","T177275-","A177276-","T177277-","A177278-","T177279-","C177280-","A177281-","T177282-","T177283-","A177284-","A177285-","A177286-","G177287-","A177288-","C177289-","A177290-","G177291-","A177292-","C177293-","G177294-","A177295-","T177296-","G177297-","G177298-","T177299-","A177300-","A177301-","A177302-","A177303-","C177304-","T177305-","G177306-","T177307-","A177308-","T177309-","T177310-","T177311-","G177312-","A177313-","T177314-","T177315-","T177316-","A177317-","T177318-","C177319-","G177320-","T177321-","T177322-","A177323-","T177324-","G177325-","T177326-","A177327-","G177328-","T177329-","T177330-","A177331-","C177332-","A177333-","T177334-","T177335-","C177336-","C177337-","T177338-","C177339-","T177340-","T177341-","A177342-","A177343-","A177344-","T177345-","G177346-","G177347-","A177348-","C177349-","T177350-","A177351-","G177352-","C177353-","T177354-","T177355-","T177356-","T177357-","T177358-","G177359-","A177360-","T177361-","T177362-","A177363-","G177364-","T177365-","C177366-","G177367-","T177368-","C177369-","T177370-","A177371-","C177372-","C177373-","G177374-","C177375-","C177376-","T177377-","A177378-","A177379-","A177380-","A177381-","G177382-","T177383-","G177384-","T177385-","C177386-","A177387-","T177388-","A177389-","T177390-","G177391-","C177392-","T177393-","C177394-","A177395-","C177396-","T177397-","G177398-","A177399-","C177400-","T177401-","A177402-","A177403-","C177404-","C177405-","A177406-","T177407-","A177408-","T177409-","A177410-","A177411-","T177412-","A177413-","G177414-","A177415-","T177416-","T177417-","A177418-","T177419-","G177420-","T177421-","T177422-","C177423-","T177424-","T177425-","A177426-","C177427-","G177428-","A177429-","A177430-","C177431-","A177432-","A177433-","T177434-","A177435-","G177436-","A177437-","C177438-","G177439-","T177440-","A177441-","T177442-","T177443-","A177444-","T177445-","T177446-","T177447-","G177448-","G177449-","C177450-","A177451-","G177452-","A177453-","G177454-","T177455-","C177456-","A177457-","A177458-","A177459-","T177460-","G177461-","A177462-","T177463-","T177464-","A177465-","A177466-","T177467-","A177468-","A177469-","G177470-","T177471-","A177472-","C177473-","G177474-","T177475-","A177476-","C177477-","T177478-","G177479-","T177480-","T177481-","A177482-","C177483-","T177484-","G177485-","G177486-","A177487-","C177488-","C177489-","C177490-","A177491-","T177492-","C177493-","C177494-","T177495-","T177496-","T177497-","T177498-","A177499-","T177500-","T177501-","A177502-","T177503-","A177504-","G177505-","A177506-","T177507-","T177508-","C177509-","A177510-","G177511-","A177512-","A177513-","A177514-","T177515-","G177516-","T177517-","T177518-","A177519-","T177520-","C177521-","G177522-","A177523-","A177524-","A177525-","A177526-","C177527-","A177528-","A177529-","A177530-","T177531-","T177532-","A177533-","G177534-","A177535-","C177536-","C177537-","A177538-","A177539-","T177540-","A177541-","C177542-","A177543-","A177544-","T177545-","A177546-","A177547-","T177548-","C177549-","G177550-","T177551-","T177552-","A177553-","T177554-","A177555-","A177556-","T177557-","A177558-","T177559-","G177560-","T177561-","T177562-","C177563-","G177564-","A177565-","A177566-","C177567-","A177568-","C177569-","G177570-","A177571-","T177572-","A177573-","G177574-","G177575-","G177576-","A177577-","C177578-","G177579-","T177580-","T177581-","A177582-","A177583-","T177584-","G177585-","A177586-","A177587-","A177588-","A177589-","G177590-","T177591-","A177592-","T177593-","G177594-","G177595-","C177596-","A177597-","A177598-","A177599-","G177600-","T177601-","C177602-","T177603-","T177604-","A177605-","C177606-","A177607-","T177608-","G177609-","A177610-","C177611-","C177612-","T177613-","C177614-","G177615-","A177616-","T177617-","A177618-","C177619-","A177620-","T177621-","A177622-","T177623-","A177624-","T177625-","C177626-","A177627-","A177628-","G177629-","G177630-","A177631-","T177632-","G177633-","T177634-","A177635-","C177636-","A177637-","A177638-","G177639-","T177640-","A177641-","T177642-","T177643-","A177644-","A177645-","A177646-","A177647-","T177648-","C177649-","T177650-","A177651-","C177652-","T177653-","T177654-","C177655-","C177656-","A177657-","T177658-","C177659-","A177660-","C177661-","T177662-","A177663-","A177664-","T177665-","A177666-","A177667-","T177668-","A177669-","T177670-","A177671-","A177672-","C177673-","A177674-","C177675-","T177676-","A177677-","T177678-","A177679-","C177680-","G177681-","A177682-","C177683-","A177684-","C177685-","T177686-","A177687-","T177688-","T177689-","A177690-","T177691-","A177692-","A177693-","A177694-","T177695-","A177696-","A177697-","T177698-","A177699-","A177700-","G177701-","T177702-","C177703-","A177704-","G177705-","A177706-","G177707-","T177708-","T177709-","T177710-","C177711-","C177712-","T177713-","A177714-","T177715-","A177716-","C177717-","G177718-","T177719-","C177720-","G177721-","T177722-","G177723-","T177724-","A177725-","A177726-","A177727-","C177728-","G177729-","A177730-","C177731-","A177732-","A177733-","A177734-","C177735-","A177736-","A177737-","T177738-","T177739-","A177740-","A177741-","T177742-","T177743-","A177744-","A177745-","T177746-","C177747-","T177748-","C177749-","A177750-","T177751-","A177752-","A177753-","A177754-","A177755-","T177756-","C177757-","C177758-","A177759-","A177760-","T177761-","A177762-","C177763-","A177764-","T177765-","A177766-","T177767-","C177768-","A177769-","T177770-","A177771-","A177772-","T177773-","C177774-","T177775-","T177776-","A177777-","T177778-","C177779-","G177780-","A177781-","A177782-","A177783-","A177784-","A177785-","G177786-","T177787-","T177788-","A177789-","T177790-","T177791-","A177792-","A177793-","A177794-","A177795-","A177796-","T177797-","A177798-","C177799-","A177800-","T177801-","T177802-","A177803-","G177804-","A177805-","G177806-","A177807-","A177808-","A177809-","T177810-","A177811-","T177812-","A177813-","C177814-","T177815-","T177816-","T177817-","A177818-","A177819-","C177820-","T177821-","A177822-","A177823-","T177824-","A177825-","T177826-","A177827-","G177828-","T177829-","C177830-","C177831-","T177832-","C177833-","G177834-","A177835-","G177836-","T177837-","A177838-","T177839-","A177840-","T177841-","G177842-","A177843-","T177844-","C177845-","T177846-","C177847-","A177848-","T177849-","C177850-","T177851-","C177852-","G177853-","A177854-","T177855-","C177856-","T177857-","C177858-","A177859-","A177860-","T177861-","C177862-","A177863-","T177864-","C177865-","T177866-","T177867-","A177868-","T177869-","T177870-","T177871-","G177872-","A177873-","G177874-","T177875-","C177876-","G177877-","T177878-","A177879-","T177880-","T177881-","C177882-","C177883-","T177884-","A177885-","A177886-","T177887-","G177888-","A177889-","G177890-","A177891-","T177892-","A177893-","T177894-","T177895-","A177896-","C177897-","T177898-","C177899-","G177900-","A177901-","A177902-","A177903-","T177904-","A177905-","T177906-","T177907-","A177908-","T177909-","A177910-","T177911-","A177912-","A177913-","A177914-","C177915-","T177916-","C177917-","G177918-","A177919-","C177920-","A177921-","T177922-","G177923-","T177924-","A177925-","C177926-","G177927-","A177928-","T177929-","T177930-","T177931-","A177932-","C177933-","G177934-","T177935-","A177936-","A177937-","T177938-","C177939-","T177940-","A177941-","T177942-","A177943-","T177944-","A177945-","C177946-","A177947-","A177948-","G177949-","A177950-","T177951-","A177952-","T177953-","A177954-","T177955-","G177956-","A177957-","G177958-","A177959-","G177960-","A177961-","G177962-","A177963-","A177964-","T177965-","G177966-","A177967-","T177968-","A177969-","T177970-","C177971-","A177972-","C177973-","A177974-","G177975-","A177976-","G177977-","T177978-","A177979-","T177980-","C177981-","A177982-","T177983-","A177984-","T177985-","A177986-","G177987-","A177988-","G177989-","A177990-","A177991-","T177992-","A177993-","C177994-","G177995-","A177996-","G177997-","G177998-","T177999-","C178000-","T178001-","G178002-","T178003-","T178004-","T178005-","C178006-","T178007-","A178008-","C178009-","A178010-","C178011-","A178012-","G178013-","A178014-","C178015-","A178016-","T178017-","G178018-","A178019-","A178020-","T178021-","A178022-","A178023-","T178024-","G178025-","A178026-","A178027-","T178028-","A178029-","C178030-","A178031-","C178032-","A178033-","T178034-","A178035-","C178036-","A178037-","A178038-","C178039-","G178040-","T178041-","T178042-","T178043-","T178044-","T178045-","T178046-","T178047-","T178048-","A178049-","A178050-","T178051-","C178052-","T178053-","T178054-","A178055-","G178056-","A178057-","T178058-","A178059-","T178060-","A178061-","A178062-","C178063-","A178064-","C178065-","T178066-","A178067-","A178068-","T178069-","T178070-","A178071-","C178072-","A178073-","T178074-","C178075-","A178076-","A178077-","G178078-","A178079-","T178080-","T178081-","A178082-","T178083-","A178084-","T178085-","A178086-","T178087-","T178088-","G178089-","A178090-","A178091-","A178092-","T178093-","C178094-","G178095-","T178096-","A178097-","A178098-","T178099-","T178100-","T178101-","G178102-","A178103-","G178104-","T178105-","T178106-","G178107-","T178108-","C178109-","T178110-","G178111-","A178112-","T178113-","C178114-","A178115-","T178116-","C178117-","A178118-","T178119-","G178120-","G178121-","A178122-","T178123-","A178124-","T178125-","C178126-","G178127-","A178128-","A178129-","A178130-","A178131-","T178132-","A178133-","A178134-","T178135-","A178136-","T178137-","A178138-","C178139-","G178140-","T178141-","A178142-","A178143-","C178144-","A178145-","T178146-","T178147-","A178148-","G178149-","C178150-","A178151-","A178152-","T178153-","C178154-","T178155-","T178156-","T178157-","T178158-","A178159-","G178160-","A178161-","T178162-","G178163-","A178164-","T178165-","T178166-","G178167-","A178168-","T178169-","A178170-","T178171-","A178172-","T178173-","T178174-","A178175-","T178176-","T178177-","A178178-","T178179-","G178180-","C178181-","G178182-","A178183-","T178184-","G178185-","T178186-","A178187-","A178188-","T178189-","C178190-","A178191-","T178192-","A178193-","A178194-","C178195-","T178196-","A178197-","T178198-","C178199-","G178200-","G178201-","A178202-","G178203-","A178204-","T178205-","G178206-","T178207-","A178208-","G178209-","A178210-","A178211-","A178212-","T178213-","T178214-","A178215-","A178216-","A178217-","G178218-","C178219-","G178220-","C178221-","A178222-","T178223-","A178224-","A178225-","A178226-","A178227-","C178228-","T178229-","A178230-","T178231-","T178232-","T178233-","T178234-","G178235-","G178236-","T178237-","T178238-","G178239-","C178240-","C178241-","G178242-","G178243-","A178244-","T178245-","C178246-","T178247-","A178248-","C178249-","G178250-","T178251-","A178252-","T178253-","T178254-","T178255-","T178256-","A178257-","A178258-","A178259-","A178260-","C178261-","A178262-","A178263-","T178264-","G178265-","T178266-","T178267-","C178268-","A178269-","C178270-","A178271-","A178272-","C178273-","A178274-","T178275-","C178276-","T178277-","A178278-","T178279-","G178280-","A178281-","T178282-","A178283-","G178284-","C178285-","G178286-","A178287-","G178288-","A178289-","G178290-","A178291-","T178292-","C178293-","T178294-","A178295-","G178296-","C178297-","A178298-","A178299-","C178300-","T178301-","A178302-","G178303-","A178304-","G178305-","T178306-","A178307-","A178308-","A178309-","T178310-","A178311-","T178312-","A178313-","C178314-","A178315-","G178316-","A178317-","T178318-","G178319-","T178320-","T178321-","C178322-","G178323-","A178324-","T178325-","A178326-","A178327-","A178328-","G178329-","A178330-","T178331-","G178332-","C178333-","C178334-","G178335-","T178336-","C178337-","A178338-","A178339-","A178340-","A178341-","A178342-","T178343-","A178344-","T178345-","T178346-","G178347-","T178348-","A178349-","C178350-","A178351-","G178352-","T178353-","A178354-","C178355-","T178356-","T178357-","A178358-","T178359-","A178360-","C178361-","A178362-","A178363-","T178364-","A178365-","G178366-","G178367-","T178368-","A178369-","T178370-","A178371-","T178372-","A178373-","A178374-","G178375-","T178376-","T178377-","C178378-","T178379-","A178380-","T178381-","G178382-","A178383-","A178384-","T178385-","G178386-","T178387-","G178388-","A178389-","T178390-","A178391-","G178392-","A178393-","C178394-","A178395-","T178396-","A178397-","T178398-","T178399-","A178400-","A178401-","A178402-","A178403-","T178404-","G178405-","C178406-","A178407-","C178408-","C178409-","G178410-","A178411-","C178412-","T178413-","A178414-","A178415-","G178416-","A178417-","A178418-","C178419-","G178420-","T178421-","A178422-","A178423-","A178424-","A178425-","C178426-","G178427-","A178428-","A178429-","C178430-","T178431-","A178432-","T178433-","A178434-","G178435-","A178436-","A178437-","T178438-","G178439-","T178440-","T178441-","A178442-","T178443-","A178444-","C178445-","A178446-","A178447-","T178448-","G178449-","G178450-","G178451-","T178452-","G178453-","A178454-","T178455-","G178456-","A178457-","T178458-","A178459-","A178460-","G178461-","T178462-","A178463-","G178464-","A178465-","A178466-","G178467-","A178468-","T178469-","G178470-","T178471-","T178472-","A178473-","C178474-","C178475-","C178476-","G178477-","A178478-","T178479-","A178480-","T178481-","A178482-","C178483-","C178484-","C178485-","A178486-","T178487-","A178488-","G178489-","C178490-","A178491-","T178492-","T178493-","A178494-","T178495-","C178496-","T178497-","A178498-","G178499-","T178500-","T178501-","A178502-","T178503-","G178504-","G178505-","C178506-","A178507-","T178508-","G178509-","T178510-","G178511-","T178512-","G178513-","T178514-","A178515-","T178516-","T178517-","A178518-","G178519-","A178520-","T178521-","C178522-","A178523-","A178524-","T178525-","A178526-","C178527-","A178528-","T178529-","A178530-","T178531-","A178532-","C178533-","A178534-","T178535-","T178536-","A178537-","T178538-","A178539-","A178540-","G178541-","C178542-","G178543-","G178544-","T178545-","C178546-","G178547-","T178548-","A178549-","C178550-","C178551-","C178552-","A178553-","A178554-","C178555-","A178556-","C178557-","T178558-","G178559-","A178560-","T178561-","T178562-","A178563-","T178564-","A178565-","C178566-","A178567-","T178568-","C178569-","G178570-","G178571-","T178572-","A178573-","C178574-","A178575-","T178576-","A178577-","C178578-","A178579-","G178580-","T178581-","A178582-","A178583-","A178584-","T178585-","A178586-","G178587-","C178588-","A178589-","T178590-","A178591-","G178592-","A178593-","T178594-","A178595-","T178596-","G178597-","G178598-","A178599-","G178600-","G178601-","A178602-","G178603-","G178604-","A178605-","T178606-","A178607-","C178608-","A178609-","A178610-","A178611-","T178612-","A178613-","T178614-","T178615-","T178616-","C178617-","A178618-","A178619-","A178620-","T178621-","A178622-","A178623-","A178624-","G178625-","T178626-","T178627-","A178628-","T178629-","G178630-","A178631-","G178632-","A178633-","T178634-","A178635-","C178636-","G178637-","C178638-","G178639-","C178640-","T178641-","G178642-","T178643-","C178644-","A178645-","A178646-","T178647-","A178648-","A178649-","T178650-","A178651-","T178652-","A178653-","T178654-","G178655-","G178656-","A178657-","A178658-","G178659-","A178660-","C178661-","A178662-","T178663-","T178664-","A178665-","C178666-","C178667-","T178668-","A178669-","A178670-","C178671-","T178672-","T178673-","C178674-","T178675-","G178676-","A178677-","A178678-","C178679-","T178680-","G178681-","G178682-","A178683-","A178684-","C178685-","T178686-","A178687-","T178688-","A178689-","A178690-","A178691-","T178692-","C178693-","C178694-","A178695-","G178696-","G178697-","C178698-","T178699-","C178700-","T178701-","C178702-","G178703-","C178704-","A178705-","T178706-","A178707-","A178708-","A178709-","G178710-","A178711-","T178712-","G178713-","A178714-","A178715-","T178716-","A178717-","T178718-","A178719-","T178720-","A178721-","T178722-","G178723-","T178724-","T178725-","G178726-","T178727-","A178728-","T178729-","G178730-","C178731-","G178732-","A178733-","C178734-","A178735-","T178736-","C178737-","A178738-","A178739-","A178740-","G178741-","A178742-","T178743-","G178744-","A178745-","A178746-","A178747-","A178748-","A178749-","A178750-","T178751-","G178752-","T178753-","T178754-","A178755-","A178756-","G178757-","A178758-","C178759-","T178760-","T178761-","A178762-","T178763-","A178764-","T178765-","A178766-","T178767-","T178768-","T178769-","A178770-","G178771-","A178772-","T178773-","A178774-","T178775-","A178776-","A178777-","C178778-","A178779-","C178780-","G178781-","A178782-","A178783-","T178784-","A178785-","T178786-","G178787-","T178788-","A178789-","T178790-","G178791-","A178792-","C178793-","G178794-","G178795-","A178796-","T178797-","G178798-","G178799-","G178800-","A178801-","A178802-","T178803-","T178804-","G178805-","G178806-","T178807-","A178808-","A178809-","C178810-","G178811-","A178812-","T178813-","G178814-","A178815-","C178816-","A178817-","G178818-","A178819-","A178820-","A178821-","G178822-","C178823-","A178824-","G178825-","A178826-","T178827-","T178828-","G178829-","T178830-","C178831-","A178832-","G178833-","C178834-","T178835-","C178836-","T178837-","G178838-","C178839-","A178840-","T178841-","A178842-","C178843-","T178844-","A178845-","T178846-","T178847-","C178848-","T178849-","T178850-","C178851-","A178852-","T178853-","G178854-","A178855-","C178856-","A178857-","A178858-","T178859-","A178860-","C178861-","C178862-","A178863-","T178864-","A178865-","A178866-","T178867-","G178868-","A178869-","T178870-","G178871-","T178872-","T178873-","A178874-","C178875-","A178876-","T178877-","T178878-","G178879-","T178880-","T178881-","A178882-","T178883-","G178884-","A178885-","A178886-","G178887-","C178888-","G178889-","T178890-","A178891-","T178892-","A178893-","T178894-","G178895-","T178896-","T178897-","A178898-","C178899-","A178900-","A178901-","G178902-","A178903-","T178904-","A178905-","C178906-","A178907-","T178908-","T178909-","T178910-","A178911-","A178912-","T178913-","G178914-","T178915-","G178916-","C178917-","T178918-","T178919-","A178920-","C178921-","G178922-","G178923-","A178924-","A178925-","C178926-","A178927-","T178928-","A178929-","T178930-","A178931-","T178932-","T178933-","T178934-","A178935-","G178936-","A178937-","A178938-","A178939-","C178940-","A178941-","T178942-","C178943-","T178944-","A178945-","C178946-","T178947-","A178948-","A178949-","C178950-","G178951-","A178952-","T178953-","T178954-","T178955-","T178956-","T178957-","T178958-","A178959-","T178960-","G178961-","C178962-","T178963-","T178964-","G178965-","T178966-","A178967-","T178968-","T178969-","A178970-","T178971-","T178972-","A178973-","A178974-","T178975-","G178976-","G178977-","T178978-","A178979-","T178980-","G178981-","T178982-","A178983-","A178984-","T178985-","A178986-","T178987-","G178988-","A178989-","T178990-","T178991-","T178992-","A178993-","A178994-","T178995-","T178996-","G178997-","A178998-","T178999-","T179000-","G179001-","T179002-","G179003-","T179004-","A179005-","C179006-","A179007-","C179008-","G179009-","A179010-","T179011-","A179012-","C179013-","C179014-","A179015-","A179016-","T179017-","T179018-","T179019-","G179020-","T179021-","C179022-","G179023-","A179024-","G179025-","T179026-","A179027-","T179028-","G179029-","A179030-","A179031-","T179032-","A179033-","C179034-","G179035-","G179036-","A179037-","G179038-","T179039-","A179040-","C179041-","A179042-","A179043-","A179044-","C179045-","A179046-","T179047-","A179048-","A179049-","A179050-","C179051-","T179052-","G179053-","A179054-","A179055-","G179056-","T179057-","T179058-","T179059-","A179060-","A179061-","C179062-","A179063-","T179064-","T179065-","A179066-","T179067-","T179068-","T179069-","A179070-","T179071-","T179072-","T179073-","A179074-","T179075-","G179076-","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G181052-","A181114-","T181115-","T181116-","C181117-","C181118-","T181119-","T181120-","A181121-","T181122-","A181253-","C183555-","T183556-","A183557-","T187080-","T187207-","T187775-","T189744-","A190198-","C190199-","A190402-","A192435-","A192436-","G192437-","T192438-","C192439-","A192440-","T192441-","A192442-","A192443-","G192444-","T192445-","T192446-","A192447-","G192448-","T192449-","T192450-","A192451-","A192452-","G192453-","T192454-","C192455-","A192456-","T192457-","A192458-","A192459-","G192460-","T192461-","T192462-","A192463-","G192464-","T192465-","T192466-","A192467-","A192468-","G192469-","T192470-","C192471-","A192472-","T192473-","A192474-","A192475-","G192476-","T192477-","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-","A192490-","A192491-","G192492-","T192493-","T192494-","A192495-","G192496-","T192497-","T192498-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T193611C"],"OPG002":["V172-"],"OPG003_dup":["Y337H"],"OPG021":["I232-"],"OPG029":["D153-","D154-"],"OPG031":["G258-"],"OPG044":["K147-"],"OPG049":["R314-"],"OPG084":["F11-"],"OPG105":["K282-"],"OPG117":["F502-"],"OPG122":["S108-"],"OPG133":["G144-"],"OPG145":["M17-"],"OPG149":["K186-"],"OPG151":["N4-"],"OPG157":["Q61-"],"OPG159":["N124-","Y125-","N126-"],"OPG164":["V228-"],"OPG173":["K35-"],"OPG180":["N245-","L555-"],"OPG188":["K437-"],"OPG191":["F166-"],"OPG193":["F263-"],"OPG197":["S18-","D19-","E37-","D38-","I39-","M40-","N41-","E42-","I43-"],"OPG198":["K231-"],"OPG209":["G179-"],"OPG210":["L734-"]},"labels":{"aa":"OPG002: V172-; OPG003_dup: Y337H; OPG021: I232-; OPG029: D153-, D154-; OPG031: G258-; OPG044: K147-; OPG049: R314-; OPG084: F11-; OPG105: K282-; OPG117: F502-; OPG122: S108-; OPG133: G144-; OPG145: M17-; OPG149: K186-; OPG151: N4-; OPG157: Q61-; OPG159: N124-, Y125-, N126-; OPG164: V228-; OPG173: K35-; OPG180: N245-, L555-; OPG188: K437-; OPG191: F166-; OPG193: F263-; OPG197: S18-, D19-, E37-, D38-, I39-, M40-, N41-, E42-, I43-; OPG198: K231-; OPG209: G179-; OPG210: L734-"}}},{"name":"OP245338","node_attrs":{"div":0,"accession":"OP245338","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP245338/2022-07-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-20"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"MPX/PT0088/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OP215275","node_attrs":{"div":2,"accession":"OP215275","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP215275/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI256"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G72097A","C145842T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG092":["S284F"]},"labels":{"aa":"OPG092: S284F"}}},{"name":"OP245306","node_attrs":{"div":2,"accession":"OP245306","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP245306/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"MPX/PT0049/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C804-","A805-","C73616T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159132T","T196639-","T196640-"],"OPG185":["K72N"]},"labels":{"aa":"OPG185: K72N"}}},{"name":"OP205130","node_attrs":{"div":3,"accession":"OP205130","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205130/2022-06-29"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-29"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000185"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G33274A","C47537T","G68286A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP205125","node_attrs":{"div":2,"accession":"OP205125","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205125/2022-06-24"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-24"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000175"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C27537T","G118790A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG043":["R140K"]},"labels":{"aa":"OPG043: R140K"}}},{"name":"OP205126","node_attrs":{"div":0,"accession":"OP205126","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205126/2022-06-26"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-26"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000177"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP205115","node_attrs":{"div":1,"accession":"OP205115","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205115/2022-07-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-07"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000157"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C78232T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP205074","node_attrs":{"div":0,"accession":"OP205074","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205074/2022-06-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-07"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000068"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP450993","node_attrs":{"div":1,"accession":"OP450993","author":{"author":"Gigante,C.M.,Pettit,D.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Deutsch-Feldman,M.,Li,Y.","value":"Gigante,C.M.,Pettit,D.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Deutsch-Feldman,M.,Li,Y."},"strain_display":{"value":"USA/OP450993/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_NC0004"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T4775-","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","C125311T","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP422245","node_attrs":{"div":0,"accession":"OP422245","author":{"author":"Laubscher,F.,Chudzinsk,V.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinsk,V.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A."},"strain_display":{"value":"Switzerland/OP422245/2022-05-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"date":{"value":"2022-05-30"},"lineage":{"value":"B.1"},"country":{"value":"Switzerland"},"strain":{"value":"hMPXV-CH-38212023/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OP415226","node_attrs":{"div":0,"accession":"OP415226","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415226/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_k9tr7U_9000256"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A173518-","G173519-","A173520-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP415217","node_attrs":{"div":1,"accession":"OP415217","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415217/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_I1tnVS_9000246"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G121770A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG141":["A52V"]},"labels":{"aa":"OPG141: A52V"}}},{"name":"OP415196","node_attrs":{"div":0,"accession":"OP415196","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415196/2022-03-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-03-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_96X1Vd_9000218"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP415194","node_attrs":{"div":0,"accession":"OP415194","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415194/2022-03-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-03-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_96X1Vd_9000216"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP414363","node_attrs":{"div":0,"accession":"OP414363","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP414363/2022-05-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-05-27"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0332/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A","-196616T"]}}},{"name":"OP414381","node_attrs":{"div":0,"accession":"OP414381","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP414381/2022-05-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-05-23"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0354/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196616T"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-"}}},{"name":"OP414352","node_attrs":{"div":2,"accession":"OP414352","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP414352/2022-06-04"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-06-04"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0320/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C4592T","G11462A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G192618A"],"OPG003":["E6K"],"OPG003_dup":["E6K"],"OPG023":["S480L"]},"labels":{"aa":"OPG003: E6K; OPG003_dup: E6K; OPG023: S480L"}}},{"name":"OP414357","node_attrs":{"div":0,"accession":"OP414357","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP414357/2022-06-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-06-03"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0325/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP414358","node_attrs":{"div":0,"accession":"OP414358","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP414358/2022-06-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-06-02"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0326/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP414305","node_attrs":{"div":1,"accession":"OP414305","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP414305/2022-06-17"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-06-17"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0265/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G25030A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"],"OPG040":["S150F"]},"labels":{"aa":"OPG040: S150F"}}},{"name":"OP382494","node_attrs":{"div":0,"accession":"OP382494","author":{"author":"Colson,P.","value":"Colson,P."},"strain_display":{"value":"France/OP382494/2022-07-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-22"},"lineage":{"value":"B.1"},"country":{"value":"France"},"strain":{"value":"hMPXV-IHU00017"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP382490","node_attrs":{"div":0,"accession":"OP382490","author":{"author":"Colson,P.","value":"Colson,P."},"strain_display":{"value":"France/OP382490/2022-07-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-20"},"lineage":{"value":"B.1"},"country":{"value":"France"},"strain":{"value":"hMPXV-IHU00013"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP382495","node_attrs":{"div":1,"accession":"OP382495","author":{"author":"Colson,P.","value":"Colson,P."},"strain_display":{"value":"France/OP382495/2022-07-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-22"},"lineage":{"value":"B.1"},"country":{"value":"France"},"strain":{"value":"hMPXV-IHU00018"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G100498A","-179222T","-179223A","-179224T","-179225A"],"OPG119":["R38K"]},"labels":{"aa":"OPG119: R38K"}}},{"name":"OP382478","node_attrs":{"div":1,"accession":"OP382478","author":{"author":"Colson,P.","value":"Colson,P."},"strain_display":{"value":"France/OP382478/2022-06-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-06-13"},"lineage":{"value":"B.1"},"country":{"value":"France"},"strain":{"value":"hMPXV-IHU00001"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C178006T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG205":["S784F"]},"labels":{"aa":"OPG205: S784F"}}},{"name":"OP382483","node_attrs":{"div":0,"accession":"OP382483","author":{"author":"Colson,P.","value":"Colson,P."},"strain_display":{"value":"France/OP382483/2022-07-04"},"host":{"value":"Homo sapiens"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-04"},"lineage":{"value":"B.1"},"country":{"value":"France"},"strain":{"value":"hMPXV-IHU00006"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OP555540","node_attrs":{"div":1,"accession":"OP555540","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555540/2022-08-04"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-04"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0459/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C81657T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG105":["P178S"]},"labels":{"aa":"OPG105: P178S"}}},{"name":"OP555524","node_attrs":{"div":0,"accession":"OP555524","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555524/2022-08-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-03"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0442/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP539930","node_attrs":{"div":2,"accession":"OP539930","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OP539930/2022-08-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-08-30"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00145/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","G94221A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C188391T","A196765-","T196766-","T196767-"],"OPG113":["E831K"]},"labels":{"aa":"OPG113: E831K"}}},{"name":"OP536811","node_attrs":{"div":2,"accession":"OP536811","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536811/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"9000448"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C95004T","G111541A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG130":["S121F"]},"labels":{"aa":"OPG130: S121F"}}},{"name":"OP536805","node_attrs":{"div":2,"accession":"OP536805","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536805/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"9000435"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","A53995G","C124495T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OP484686","node_attrs":{"div":2,"accession":"OP484686","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP484686/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI365"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179588T","C183534A"],"OPG208":["A108V"],"OPG210":["P727T"]},"labels":{"aa":"OPG208: A108V; OPG210: P727T"}}},{"name":"OP628444","node_attrs":{"div":2,"accession":"OP628444","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OP628444/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-081603/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C24818T","T150805A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG040":["E221K"]},"labels":{"aa":"OPG040: E221K"}}},{"name":"OP605584","node_attrs":{"div":4,"accession":"OP605584","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605584/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-43-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A33-","-607T","C8385T","T33995A","A86934G","G91904A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG052":["M1L"]},"labels":{"aa":"OPG052: M1L"}}},{"name":"OP605580","node_attrs":{"div":1,"accession":"OP605580","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605580/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-39-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C179082T","C179091T","T179094A","C179100T","T179103A","C179109T","T179112A","C179118T","T179121A","C179127T","T179130A","C179136T","C179145T","T179148A","C179154T","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179239A","-179240T","-179241A","-179242T","-179243A","G189288A"]}}},{"name":"OP605573","node_attrs":{"div":0,"accession":"OP605573","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605573/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-31-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","A120644-","T120645-","T120646-","A120647-","G120648-","T120649-","G120650-","G120651-","G120652-","C120653-","A120654-","T120655-","C120656-","T120657-","T120658-","T120659-","T120660-","T120661-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179216A","-179217C","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG138":["M160-","P161-","T162-","N163-","K164-","K165-"]},"labels":{"aa":"OPG138: M160-, P161-, T162-, N163-, K164-, K165-"}}},{"name":"OP605582","node_attrs":{"div":10,"accession":"OP605582","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605582/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-41-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C198-","-607T","C27187T","G176523A","C176524T","T176532G","G176536C","A176544T","A176550T","A176551G","T176552C","A176559C","T179059G","T179072A","G179076T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG043":["D257N"],"OPG205":["A290Y","I297L","N299C"]},"labels":{"aa":"OPG043: D257N; OPG205: A290Y, I297L, N299C"}}},{"name":"OP605571","node_attrs":{"div":2,"accession":"OP605571","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605571/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-29-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T264-","-607T","A86557T","A120644-","T120645-","T120646-","A120647-","G120648-","T120649-","G120650-","G120651-","G120652-","C120653-","A120654-","T120655-","C120656-","T120657-","T120658-","T120659-","T120660-","T120661-","C168661T","G173318A","G173319T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG108":["I168K"],"OPG138":["M160-","P161-","T162-","N163-","K164-","K165-"]},"labels":{"aa":"OPG108: I168K; OPG138: M160-, P161-, T162-, N163-, K164-, K165-"}}},{"name":"OP605569","node_attrs":{"div":2,"accession":"OP605569","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605569/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-27-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G104565A","G130432A","T179166A","-179172C","-179173A","-179174G","-179175T","-179176A","-179177T","-179178C","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185G","-179186T","-179187T","-179188T","-179189A","-179190G","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197A","-179198T","-179199C","-179200C","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208A","-179209T","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217T","-179218A","-179219T","-179220C","-179221A","-179222T","-179223A","-179224T","-179225C","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236T","-179237T","-179238T","-179239A","-179240C","-179241A","-179242T","-179243A","T179248A","T179254A","G179256C","T179258G","A179261T","G179269A","T179271C","A179272G"],"OPG123":["S169F"],"OPG208":["D2N","I3V"]},"labels":{"aa":"OPG123: S169F; OPG208: D2N, I3V"}}},{"name":"OP605559","node_attrs":{"div":1,"accession":"OP605559","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605559/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-17-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G163460A","C196891-","T196892-","A196893-"],"OPG189":["R43Q"]},"labels":{"aa":"OPG189: R43Q"}}},{"name":"OP605565","node_attrs":{"div":0,"accession":"OP605565","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605565/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-23-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP605566","node_attrs":{"div":1,"accession":"OP605566","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605566/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-24-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","C167944T","G196973-","A196974-","A196975-"],"OPG193":["S204L"]},"labels":{"aa":"OPG193: S204L"}}},{"name":"OP605558","node_attrs":{"div":0,"accession":"OP605558","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605558/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-16-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP605561","node_attrs":{"div":0,"accession":"OP605561","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605561/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-19-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP605563","node_attrs":{"div":1,"accession":"OP605563","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605563/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-21-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","A29748T"],"OPG047":["*483K"]},"labels":{"aa":"OPG047: *483K"}}},{"name":"OP604569","node_attrs":{"div":2,"accession":"OP604569","author":{"author":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T.","value":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T."},"strain_display":{"value":"USA/OP604569/2022-09-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"date":{"value":"2022-09-14"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV22/human/USA-OK-302"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C16209T","C86604T","C133077T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG027":["E57K"]},"labels":{"aa":"OPG027: E57K"}}},{"name":"OP580156","node_attrs":{"div":4,"accession":"OP580156","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"strain_display":{"value":"USA/OP580156/2022-06-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2022-06-30"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-CDPH-MPX000009/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","C138921A","C144678T","A149457T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C189536T"],"OPG005":["S113L"],"OPG153":["D385-"],"OPG167":["D244N"],"OPG175":["I6L"]},"labels":{"aa":"OPG005: S113L; OPG153: D385-; OPG167: D244N; OPG175: I6L"}}},{"name":"OP594195","node_attrs":{"div":4,"accession":"OP594195","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP594195/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI431"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G3698A","G33851A","C128585T","C141143T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C193512T"],"OPG052":["L49F"]},"labels":{"aa":"OPG052: L49F"}}},{"name":"OP555648","node_attrs":{"div":4,"accession":"OP555648","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555648/2022-09-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-09"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0577/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G2360A","A136552-","T136553-","C136554-","G146433A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C167425T","C189174T","C194850T"],"OPG002":["T131I"],"OPG002_dup":["T131I"],"OPG153":["D385-"],"OPG170":["H116Y"],"OPG193":["S31F"]},"labels":{"aa":"OPG002: T131I; OPG002_dup: T131I; OPG153: D385-; OPG170: H116Y; OPG193: S31F"}}},{"name":"OP555646","node_attrs":{"div":2,"accession":"OP555646","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555646/2022-09-06"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-06"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0575/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","C15480T","G102204A","A136543-","T136544-","C136545-","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A","-196616T"],"OPG121":["E139K"],"OPG153":["D382-","D383-","D384-","D385-"]},"labels":{"aa":"OPG121: E139K; OPG153: D382-, D383-, D384-, D385-"}}},{"name":"OP879763","node_attrs":{"div":0,"accession":"OP879763","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"strain_display":{"value":"USA/OP879763/2022-07-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"date":{"value":"2022-07-25"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"NJ-MPXV-049"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP879744","node_attrs":{"div":1,"accession":"OP879744","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"strain_display":{"value":"USA/OP879744/2022-07-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"NJ-MPXV-028"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G111880A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG130":["S8L"]},"labels":{"aa":"OPG130: S8L"}}},{"name":"OP837355","node_attrs":{"div":0,"accession":"OP837355","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP837355/2022-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI593"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP837349","node_attrs":{"div":0,"accession":"OP837349","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP837349/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI587"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP837341","node_attrs":{"div":1,"accession":"OP837341","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP837341/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI579"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A152274G"]}}},{"name":"OP764617","node_attrs":{"div":0,"accession":"OP764617","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP764617/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI559"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP747060","node_attrs":{"div":8,"accession":"OP747060","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OP747060/2022-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-104793/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C5081T","G51559A","G71170A","C77397T","C106188T","C125865T","G166314A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G182601A","G192129A"],"OPG015":["R359K"],"OPG015_dup":["R359K"],"OPG191":["D52N"],"OPG210":["D416N"]},"labels":{"aa":"OPG015: R359K; OPG015_dup: R359K; OPG191: D52N; OPG210: D416N"}}},{"name":"OP743997","node_attrs":{"div":3,"accession":"OP743997","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OP743997/2022-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/Unknown-UW-105322/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C90945T","C103417T","C173114T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG123":["E552K"]},"labels":{"aa":"OPG123: E552K"}}},{"name":"OP727823","node_attrs":{"div":1,"accession":"OP727823","author":{"author":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K.","value":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K."},"strain_display":{"value":"Belgium/OP727823/2022-10-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-10-09"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"PrEV_case_4"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C26013T","A173314-","T173315-","A173316-","T173317-","A188351-"],"OPG042":["G362E"]},"labels":{"aa":"OPG042: G362E"}}},{"name":"OP743358","node_attrs":{"div":0,"accession":"OP743358","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"strain_display":{"value":"USA/OP743358/2022-05-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"Utah Public Health Laboratory"},"date":{"value":"2022-05-21"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200023/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP689683","node_attrs":{"div":2,"accession":"OP689683","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP689683/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI530"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G56205A","C136374T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG153":["D432N"]},"labels":{"aa":"OPG153: D432N"}}},{"name":"OP693649","node_attrs":{"div":2,"accession":"OP693649","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"strain_display":{"value":"Colombia/OP693649/2022-07-29"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-07-29"},"lineage":{"value":"B.1"},"country":{"value":"Colombia"},"strain":{"value":"ANT_INS_MPX_0039_L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A2840-","T2841-","C2842-","G127058A","G136194A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","T196865-","A196866-","G196867-"],"OPG148":["R358K"],"OPG153":["H492Y"]},"labels":{"aa":"OPG148: R358K; OPG153: H492Y"}}},{"name":"OP689681","node_attrs":{"div":1,"accession":"OP689681","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP689681/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI528"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C143845T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP689667","node_attrs":{"div":0,"accession":"OP689667","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP689667/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI514"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP689672","node_attrs":{"div":0,"accession":"OP689672","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP689672/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI519"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP689665","node_attrs":{"div":0,"accession":"OP689665","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP689665/2022-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI512"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP687927","node_attrs":{"div":1,"accession":"OP687927","author":{"author":"Gigante,C.M.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Morrison,S.S.,Seabolt,M.H.,Weigand,M.R.,Knipe,K.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y.","value":"Gigante,C.M.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Morrison,S.S.,Seabolt,M.H.,Weigand,M.R.,Knipe,K.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y."},"strain_display":{"value":"USA/OP687927/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_CA0036"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G169042A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","A196614-"]}}},{"name":"OP680509","node_attrs":{"div":1,"accession":"OP680509","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OP680509/2022-10-04"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-10-04"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00231/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G65370A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196713-","T196714-","A196715-"],"OPG084":["D217N"]},"labels":{"aa":"OPG084: D217N"}}},{"name":"OP920698","node_attrs":{"div":0,"accession":"OP920698","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"strain_display":{"value":"USA/OP920698/2022-11-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-11-02"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00360/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP890535","node_attrs":{"div":5,"accession":"OP890535","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OP890535/2022-09-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-09-27"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00301/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C2920T","C14140A","G121880A","C142593T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C174897T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G194290A"],"OPG003":["R563H"],"OPG003_dup":["R563H"],"OPG163":["T131I"]},"labels":{"aa":"OPG003: R563H; OPG003_dup: R563H; OPG163: T131I"}}},{"name":"OQ427116","node_attrs":{"div":2,"accession":"OQ427116","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"strain_display":{"value":"USA/OQ427116/2022-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_NY0041"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","T10449-","A10450-","G10451-","A10452-","T10453-","A23070-","T23071-","C23072-","T23073-","T23074-","G23075-","T23076-","C23077-","G23078-","A23079-","T23080-","G23081-","A23082-","G23083-","G23084-","A23085-","C23086-","A23087-","T23088-","A23089-","T23090-","A23091-","G23092-","T23093-","A23094-","C39547T","G152728A","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG038":["T23-","I24-","C25-","P26-","H27-","R28-","Q29-","D30-"],"OPG057":["D217N"],"OPG180":["D13N"]},"labels":{"aa":"OPG038: T23-, I24-, C25-, P26-, H27-, R28-, Q29-, D30-; OPG057: D217N; OPG180: D13N"}}},{"name":"OQ417835","node_attrs":{"div":1,"accession":"OQ417835","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ417835/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI702"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C11749-","C126664T","G150551-","A150563-","T150564-","T150567-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG148":["R227C"]},"labels":{"aa":"OPG148: R227C"}}},{"name":"OQ411312","node_attrs":{"div":1,"accession":"OQ411312","author":{"author":"Laubscher,F.,Chudzinsk,V.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinsk,V.,Schibler,M.,Kaiser,L.,Renzoni,A."},"strain_display":{"value":"Switzerland/OQ411312/2022-06-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"date":{"value":"2022-06-08"},"lineage":{"value":"B.1"},"country":{"value":"Switzerland"},"strain":{"value":"hMPXV-CH-38292866/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C87764T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG109":["E562K"]},"labels":{"aa":"OPG109: E562K"}}},{"name":"OQ348886","node_attrs":{"div":0,"accession":"OQ348886","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"strain_display":{"value":"USA/OQ348886/2022-06-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2022-06-20"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000139/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T6976-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ348880","node_attrs":{"div":2,"accession":"OQ348880","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"strain_display":{"value":"USA/OQ348880/2022-06-29"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2022-06-29"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000133/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","T6976-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","C146265T","C149364T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG170":["D172N"],"OPG174":["G11E"]},"labels":{"aa":"OPG170: D172N; OPG174: G11E"}}},{"name":"OQ348859","node_attrs":{"div":0,"accession":"OQ348859","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"strain_display":{"value":"USA/OQ348859/2022-06-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2022-06-28"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000110/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ547891","node_attrs":{"div":4,"accession":"OQ547891","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"strain_display":{"value":"USA/OQ547891/2022-06-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2022-06-27"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000166/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A708-","A709-","T710-","T6976-","G74526A","G74875A","C137639T","G145790A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG095":["E25K"],"OPG153":["G10E"]},"labels":{"aa":"OPG095: E25K; OPG153: G10E"}}},{"name":"OQ547776","node_attrs":{"div":0,"accession":"OQ547776","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ547776/2022-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI749"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OQ547754","node_attrs":{"div":0,"accession":"OQ547754","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ547754/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI727"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OQ503844","node_attrs":{"div":3,"accession":"OQ503844","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ503844/2023-01-26"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-01-26"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00468/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C6310T","A39482C","C81194T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A170123-","T170124-","A170125-","A170126-","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-","A181373-","T181374-","C181375-","T181376-","C181377-","T181378-","G181379-","G181380-","C181381-","T181382-","A181383-","T181384-","A181385-","T181386-","A181387-","T181388-","C181389-","T181390-","T181391-","A181392-","C181393-","G181394-","G181395-","T181396-","G181397-","A181398-","C181399-","A181400-","T181401-","G181402-","T181403-","T181404-","C181405-","G181406-","T181407-","G181408-","G181409-","T181410-","G181411-","T181412-","T181413-","A181414-","T181415-","G181416-","A181417-","A181418-","A181419-","C181420-","A181421-","T181422-","G181423-","T181424-","A181425-","T181426-","G181427-","A181428-","G181429-","A181430-","A181431-","A181432-","A181433-","A181434-","C181435-","T181436-","G181437-","C181438-","G181439-","T181440-","T181441-","G181442-","T181443-","A181444-","T181445-","C181446-","A181447-","T181448-","G181449-","A181450-","C181451-","G190900A"],"OPG016":["R164K"],"OPG057":["H238Q"],"OPG198":["K30-"]},"labels":{"aa":"OPG016: R164K; OPG057: H238Q; OPG198: K30-"}}},{"name":"OQ503837","node_attrs":{"div":3,"accession":"OQ503837","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ503837/2023-01-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-01-23"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00460/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C43487T","C71729T","C101983T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG063":["D68N"],"OPG121":["S65L"]},"labels":{"aa":"OPG063: D68N; OPG121: S65L"}}},{"name":"OQ503822","node_attrs":{"div":0,"accession":"OQ503822","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ503822/2022-12-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-12-12"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00417/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035729","node_attrs":{"div":2,"accession":"OR035729","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035729/2022-09-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-09-20"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_123"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C19277T","C166803T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG192":["P25S"]},"labels":{"aa":"OPG192: P25S"}}},{"name":"OR035725","node_attrs":{"div":1,"accession":"OR035725","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035725/2022-10-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_119"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-","C137999T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG154":["E18K"]},"labels":{"aa":"OPG154: E18K"}}},{"name":"OR035712","node_attrs":{"div":3,"accession":"OR035712","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035712/2022-10-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_106"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G70841A","T76015G","T133101-","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G182189A"],"OPG089":["E326K"],"OPG097":["K287N"]},"labels":{"aa":"OPG089: E326K; OPG097: K287N"}}},{"name":"OR035711","node_attrs":{"div":1,"accession":"OR035711","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035711/2022-10-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_105"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G168614A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG195":["A129T"]},"labels":{"aa":"OPG195: A129T"}}},{"name":"OR035720","node_attrs":{"div":1,"accession":"OR035720","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035720/2022-10-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_114"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C8597T","T133101-","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035709","node_attrs":{"div":1,"accession":"OR035709","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035709/2022-10-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_103"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188946T"]}}},{"name":"OR035705","node_attrs":{"div":2,"accession":"OR035705","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035705/2022-06-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-06-02"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_99"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C127215T","C142797T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG149":["S7L"],"OPG164":["S7L"]},"labels":{"aa":"OPG149: S7L; OPG164: S7L"}}},{"name":"OR035677","node_attrs":{"div":1,"accession":"OR035677","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035677/2022-06-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-06-30"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_71"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G50982A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035676","node_attrs":{"div":0,"accession":"OR035676","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035676/2022-06-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-06-30"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_70"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035680","node_attrs":{"div":1,"accession":"OR035680","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035680/2022-06-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-06-03"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_74"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A40037G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035659","node_attrs":{"div":0,"accession":"OR035659","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035659/2022-06-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-06-07"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_53"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035656","node_attrs":{"div":1,"accession":"OR035656","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035656/2022-05-31"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-05-31"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_50"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133102-","C173614T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR030945","node_attrs":{"div":5,"accession":"OR030945","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR030945/2022-07-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-19"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_34"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G23288A","C57919T","G145305A","G178435A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G183819A"],"OPG077":["R222K"],"OPG167":["P35S"],"OPG210":["D822N"]},"labels":{"aa":"OPG077: R222K; OPG167: P35S; OPG210: D822N"}}},{"name":"OR030920","node_attrs":{"div":0,"accession":"OR030920","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR030920/2022-06-24"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-06-24"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_9"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","A28532-","T76087-","A89106-","T133102-","T155424-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG044":["M148-"]},"labels":{"aa":"OPG044: M148-"}}},{"name":"OQ773482","node_attrs":{"div":2,"accession":"OQ773482","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ773482/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI863"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G75127A","G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159448A","-179188T","-179189A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"],"OPG095":["E109K"],"OPG185":["D178N"]},"labels":{"aa":"OPG095: E109K; OPG185: D178N"}}},{"name":"OQ773432","node_attrs":{"div":2,"accession":"OQ773432","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ773432/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI813"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C87915T","G150551-","A150563-","T150564-","G150565-","A150566-","T150567-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","G181593A"],"OPG109":["M511I"],"OPG210":["E80K"]},"labels":{"aa":"OPG109: M511I; OPG210: E80K"}}},{"name":"OQ721951","node_attrs":{"div":3,"accession":"OQ721951","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"strain_display":{"value":"Taiwan/OQ721951/2023-03-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"date":{"value":"2023-03-XX"},"lineage":{"value":"B.1"},"country":{"value":"Taiwan"},"strain":{"value":"MPXV/human/Taiwan/110-122438/2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133092-","T133093-","T133094-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T149983A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G160358A","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A184479G","G193496T","A193498T","A193748G","T194019G","T194021A","G194086A"],"OPG003_dup":["K298N","E299V","C473G","R495K"],"OPG176":["S59T"],"OPG210":["R1042G"]},"labels":{"aa":"OPG003_dup: K298N, E299V, C473G, R495K; OPG176: S59T; OPG210: R1042G"}}},{"name":"OQ672580","node_attrs":{"div":9,"accession":"OQ672580","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"strain_display":{"value":"Taiwan/OQ672580/2023-03-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"date":{"value":"2023-03-XX"},"lineage":{"value":"B.1"},"country":{"value":"Taiwan"},"strain":{"value":"MPXV/human/Taiwan/110-093354/2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T4795C","C39503G","G43620A","A44076G","G45563A","T69121C","T80764C","A130204G","A143123G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG057":["K231N"],"OPG064":["F608S"],"OPG087":["Y89H"],"OPG104":["N86D"],"OPG164":["T116A"]},"labels":{"aa":"OPG057: K231N; OPG064: F608S; OPG087: Y89H; OPG104: N86D; OPG164: T116A"}}},{"name":"OQ627926","node_attrs":{"div":0,"accession":"OQ627926","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"strain_display":{"value":"Italy/OQ627926/2022-05-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"},"country":{"value":"Italy"},"strain":{"value":"INMI-22932022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OQ581848","node_attrs":{"div":1,"accession":"OQ581848","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"strain_display":{"value":"Spain/OQ581848/2022-07-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"date":{"value":"2022-07-01"},"lineage":{"value":"B.1"},"country":{"value":"Spain"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0006b/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C133168-","T133169-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C174264T","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ581849","node_attrs":{"div":2,"accession":"OQ581849","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"strain_display":{"value":"Spain/OQ581849/2022-07-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1"},"country":{"value":"Spain"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0007b/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A52777C","C150418T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T169409C","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG071":["Y554*"]},"labels":{"aa":"OPG071: Y554*"}}},{"name":"OQ570421","node_attrs":{"div":2,"accession":"OQ570421","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"strain_display":{"value":"Italy/OQ570421/2022-08-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"date":{"value":"2022-08-22"},"lineage":{"value":"B.1"},"country":{"value":"Italy"},"strain":{"value":"INMI-22872022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C106275T","G111562A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG130":["S114F"]},"labels":{"aa":"OPG130: S114F"}}},{"name":"OR449678","node_attrs":{"div":0,"accession":"OR449678","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR449678/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI964"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"OR449638","node_attrs":{"div":0,"accession":"OR449638","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR449638/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI924"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G150551-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"OR353548","node_attrs":{"div":0,"accession":"OR353548","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"strain_display":{"value":"USA/OR353548/2022-08-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"Minnesota Department of Health, Public Health Laboratory"},"date":{"value":"2022-08-08"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MN-MDH-MPXV_0038"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196736-","T196737-","C196738-"]}}},{"name":"OR264462","node_attrs":{"div":0,"accession":"OR264462","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264462/2022-07-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-13"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"8_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OR264461","node_attrs":{"div":0,"accession":"OR264461","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264461/2022-07-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-13"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"8_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264418","node_attrs":{"div":0,"accession":"OR264418","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264418/2022-07-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"44_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OR264419","node_attrs":{"div":0,"accession":"OR264419","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264419/2022-07-10"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-10"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"44_C"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OR264409","node_attrs":{"div":1,"accession":"OR264409","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264409/2022-05-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"39_L"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C66718T","T179244-"],"OPG084":["S666L"]},"labels":{"aa":"OPG084: S666L"}}},{"name":"OR264387","node_attrs":{"div":0,"accession":"OR264387","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264387/2022-06-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-06-23"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"28_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264381","node_attrs":{"div":0,"accession":"OR264381","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264381/2022-07-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-19"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"26_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OR095052","node_attrs":{"div":3,"accession":"OR095052","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR095052/2022-08-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-12"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_234/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C15287T","G78975A","T133102-","G151929A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG101":["D164N"],"OPG178":["E141K"]},"labels":{"aa":"OPG101: D164N; OPG178: E141K"}}},{"name":"OR095037","node_attrs":{"div":0,"accession":"OR095037","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR095037/2022-08-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-08"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_219/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196639-","T196640-","C196641-"]}}},{"name":"OR087007","node_attrs":{"div":4,"accession":"OR087007","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR087007/2022-08-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-03"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_198/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G18442A","G98456A","C101656T","G170981A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG118":["G4E"]},"labels":{"aa":"OPG118: G4E"}}},{"name":"OR087000","node_attrs":{"div":0,"accession":"OR087000","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR087000/2022-08-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-03"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_191/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-","C136572T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG153":["E366K"]},"labels":{"aa":"OPG153: E366K"}}},{"name":"OR086976","node_attrs":{"div":0,"accession":"OR086976","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR086976/2022-07-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-27"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_167/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR086990","node_attrs":{"div":0,"accession":"OR086990","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR086990/2022-08-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-03"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_181/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR086983","node_attrs":{"div":1,"accession":"OR086983","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR086983/2022-07-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-27"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_174/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A26090-","T26091-","G28261A","T133101-","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR086969","node_attrs":{"div":0,"accession":"OR086969","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR086969/2022-07-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-27"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_160/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C196750-","T196751-","A196752-"]}}},{"name":"OR086943","node_attrs":{"div":1,"accession":"OR086943","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR086943/2022-07-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_134/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C44440T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG064":["E487K"]},"labels":{"aa":"OPG064: E487K"}}},{"name":"OR086963","node_attrs":{"div":0,"accession":"OR086963","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR086963/2022-07-15"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-15"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_154/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OX336004","node_attrs":{"div":1,"accession":"OX336004","strain_display":{"value":"Slovakia/OX336004/2022-08-26"},"host":{"value":"Homo sapiens"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"date":{"value":"2022-08-26"},"lineage":{"value":"B.1"},"country":{"value":"Slovakia"},"strain":{"value":"RNA"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C94836T","T133100-","T133101-","T133102-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"]}}},{"name":"OX261748","node_attrs":{"div":0,"accession":"OX261748","strain_display":{"value":"Slovakia/OX261748/2022-07-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"date":{"value":"2022-07-13"},"lineage":{"value":"B.1"},"country":{"value":"Slovakia"},"strain":{"value":"RNA"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"]}}},{"name":"OR759145","node_attrs":{"div":1,"accession":"OR759145","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759145/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL054/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C171732T"],"OPG199":["L249F"]},"labels":{"aa":"OPG199: L249F"}}},{"name":"OR464209","node_attrs":{"div":4,"accession":"OR464209","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"strain_display":{"value":"USA/OR464209/2022-12-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-12-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_TX0056"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C1015T","G63034A","G103173A","T133102-","C166214T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","C187620T","G196195A","A196614-"],"OPG082":["S140L"]},"labels":{"aa":"OPG082: S140L"}}},{"name":"OR463763","node_attrs":{"div":1,"accession":"OR463763","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR463763/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI786"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C1390T","C144441T","G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","A181253-"],"OPG166":["S15F"]},"labels":{"aa":"OPG166: S15F"}}},{"name":"NODE_0000044","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A28532-","T133098-","T133099-","T133100-","T133101-","T133102-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","C179091-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188252T","A196613-","A196614-"],"OPG044":["M148-"]},"labels":{"aa":"OPG044: M148-"}},"children":[{"name":"OP133005","node_attrs":{"div":1,"accession":"OP133005","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"strain_display":{"value":"Austria/OP133005/2022-07-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1"},"country":{"value":"Austria"},"strain":{"value":"hMPXV/Austria/MUW1531848/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A179077-","A179090-","A179092-","T179093-","G197058T","C197173G"]}}},{"name":"OP133004","node_attrs":{"div":1,"accession":"OP133004","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"strain_display":{"value":"Austria/OP133004/2022-07-11"},"host":{"value":"Homo sapiens"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"date":{"value":"2022-07-11"},"lineage":{"value":"B.1"},"country":{"value":"Austria"},"strain":{"value":"hMPXV/Austria/MUW1533374/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A322G","T450C","-179091T"]}}}]},{"name":"NODE_0000045","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C118421T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG136":["M389I"]},"labels":{"aa":"OPG136: M389I"}},"children":[{"name":"OP120938","node_attrs":{"div":2,"accession":"OP120938","author":{"author":"Aja-Macaya,P.,Rumbo-Feal,S.,Poza,M.,Canizares,A.,Vallejo,J.A.,Bou,G.","value":"Aja-Macaya,P.,Rumbo-Feal,S.,Poza,M.,Canizares,A.,Vallejo,J.A.,Bou,G."},"strain_display":{"value":"Spain/OP120938/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Biomedical research institute (INIBIC), Microbiology"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1"},"country":{"value":"Spain"},"strain":{"value":"MP03CHUAC"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C142607T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG163":["H136Y"]},"labels":{"aa":"OPG163: H136Y"}}},{"name":"OR264382","node_attrs":{"div":2,"accession":"OR264382","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264382/2022-07-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-19"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"26_C"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G133806A"]}}}]},{"name":"NODE_0000046","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C144546T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"],"OPG166":["S50F"]},"labels":{"aa":"OPG166: S50F"}},"children":[{"name":"OP019275","node_attrs":{"div":3,"accession":"OP019275","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"strain_display":{"value":"Austria/OP019275/2022-06-10"},"host":{"value":"Homo sapiens"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"date":{"value":"2022-06-10"},"lineage":{"value":"B.1"},"country":{"value":"Austria"},"strain":{"value":"hMPXV/Austria/MUW1525179/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","A107070C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G190319A","-196616A","-196617A"]}}},{"name":"OR473631","node_attrs":{"div":1,"accession":"OR473631","author":{"author":"Kwasiborski,A.,Hourdel,V.,Baliere,C.,Hoinard,D.,Grassin,Q.,Feher,M.,De La Porte Des Vaux,C.,Cresta,M.,Vanhomwegen,J.,Manuguerra,J.-C.,Batejat,C.,Caro,V.","value":"Kwasiborski,A.,Hourdel,V.,Baliere,C.,Hoinard,D.,Grassin,Q.,Feher,M.,De La Porte Des Vaux,C.,Cresta,M.,Vanhomwegen,J.,Manuguerra,J.-C.,Batejat,C.,Caro,V."},"strain_display":{"value":"France/OR473631/2022-06-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"Insitut Pasteur, Environment and Infectious Risks Unit"},"date":{"value":"2022-06-03"},"lineage":{"value":"B.1"},"country":{"value":"France"},"strain":{"value":"CIBU-220031"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A"]}}}]},{"name":"NODE_0000047","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C181495T"],"OPG210":["S47L"]},"labels":{"aa":"OPG210: S47L"}},"children":[{"name":"ON929069","node_attrs":{"div":4,"accession":"ON929069","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/ON929069/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI111"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G74360A","T97413A","C179853T"],"OPG094":["R194H"],"OPG117":["S455R"]},"labels":{"aa":"OPG094: R194H; OPG117: S455R"}}},{"name":"OP615265","node_attrs":{"div":3,"accession":"OP615265","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OP615265/2022-07-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-07-19"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00192/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G59922A","C149722T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG175":["S94L"]},"labels":{"aa":"OPG175: S94L"}}}]},{"name":"NODE_0000048","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C144199T"]}},"children":[{"name":"ON880520","node_attrs":{"div":1,"accession":"ON880520","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/ON880520/2022-05-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-2857/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR004151","node_attrs":{"div":3,"accession":"OR004151","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"strain_display":{"value":"USA/OR004151/2022-10-17"},"host":{"value":"Homo sapiens"},"institution":{"value":"Utah Public Health Laboratory, Utah Public Health Laboratory Infectious Disease submission group"},"date":{"value":"2022-10-17"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200667/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C80857T","C143330T"],"OPG104":["A55T"],"OPG164":["P185S"]},"labels":{"aa":"OPG104: A55T; OPG164: P185S"}}}]},{"name":"NODE_0000049","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C101074T","G138682A"],"OPG156":["S243F"]},"labels":{"aa":"OPG156: S243F"}},"children":[{"name":"OP339847","node_attrs":{"div":3,"accession":"OP339847","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP339847/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI290"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C122447T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG143":["R290K"]},"labels":{"aa":"OPG143: R290K"}}},{"name":"OR086999","node_attrs":{"div":4,"accession":"OR086999","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR086999/2022-08-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-03"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_190/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G135395A","G178410A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000050","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C132940T"]}},"children":[{"name":"OP205124","node_attrs":{"div":2,"accession":"OP205124","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205124/2022-05-26"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-05-26"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000173"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C143551T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR488002","node_attrs":{"div":2,"accession":"OR488002","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR488002/2022-05-31"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-05-31"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0684/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C132153T","C133227T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG151":["S1077L"]},"labels":{"aa":"OPG151: S1077L"}}}]},{"name":"NODE_0000051","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C17437T","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG030":["E133K"]},"labels":{"aa":"OPG030: E133K"}},"children":[{"name":"OP185715","node_attrs":{"div":1,"accession":"OP185715","author":{"author":"Gigante,C.M.,Steidley,B.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Davizon,E.S.,Li,Y.","value":"Gigante,C.M.,Steidley,B.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Davizon,E.S.,Li,Y."},"strain_display":{"value":"USA/OP185715/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_CO0002"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A"]}}},{"name":"OQ121018","node_attrs":{"div":4,"accession":"OQ121018","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,Bell,J.,Hacker,J."},"strain_display":{"value":"USA/OQ121018/2022-07-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2022-07-25"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/CA-CDPH-1000064/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G101166A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C151047T","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","C189689T","A196711-","T196712-","A196713-"],"OPG120":["Q195*"]},"labels":{"aa":"OPG120: Q195*"}}}]},{"name":"NODE_0000052","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C102355T","C113923T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG121":["S189L"],"OPG133":["D592N"]},"labels":{"aa":"OPG121: S189L; OPG133: D592N"}},"children":[{"name":"OP422340","node_attrs":{"div":2,"accession":"OP422340","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"strain_display":{"value":"Austria/OP422340/2022-07-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"date":{"value":"2022-07-13"},"lineage":{"value":"B.1"},"country":{"value":"Austria"},"strain":{"value":"hMPXV/Austria/MUW1533948/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP422343","node_attrs":{"div":2,"accession":"OP422343","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"strain_display":{"value":"Austria/OP422343/2022-08-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"date":{"value":"2022-08-08"},"lineage":{"value":"B.1"},"country":{"value":"Austria"},"strain":{"value":"hMPXV/Austria/MUW1540386/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000053","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C82676T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP415280","node_attrs":{"div":1,"accession":"OP415280","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415280/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_3LjZEY_9000355"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP415187","node_attrs":{"div":1,"accession":"OP415187","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415187/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_Q9BB92_9000206"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000054","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G151793C"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-"}},"children":[{"name":"OP414341","node_attrs":{"div":1,"accession":"OP414341","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP414341/2022-06-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-06-07"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0307/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","A196614-"]}}},{"name":"OP414285","node_attrs":{"div":1,"accession":"OP414285","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP414285/2022-06-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-06-21"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0241/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-196615A"]}}}]},{"name":"NODE_0000055","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G5444A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG015":["S238L"]},"labels":{"aa":"OPG015: S238L"}},"children":[{"name":"OP382491","node_attrs":{"div":4,"accession":"OP382491","author":{"author":"Colson,P.","value":"Colson,P."},"strain_display":{"value":"France/OP382491/2022-07-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-22"},"lineage":{"value":"B.1"},"country":{"value":"France"},"strain":{"value":"hMPXV-IHU00014"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C20105T","A83680T","G101344A","C191766T"],"OPG015_dup":["S238L"],"OPG105":["D852V"]},"labels":{"aa":"OPG015_dup: S238L; OPG105: D852V"}}},{"name":"OR035717","node_attrs":{"div":3,"accession":"OR035717","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035717/2022-10-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_111"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G113430A","T133101-","T133102-","G177160A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","T196712-","A196713-","T196714-"],"OPG205":["R502K"]},"labels":{"aa":"OPG205: R502K"}}}]},{"name":"NODE_0000056","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C73609T","C113740T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG093":["S211L"],"OPG133":["D653N"]},"labels":{"aa":"OPG093: S211L; OPG133: D653N"}},"children":[{"name":"OP484677","node_attrs":{"div":4,"accession":"OP484677","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP484677/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI356"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G75525A","A180436G"],"OPG095":["M241I"]},"labels":{"aa":"OPG095: M241I"}}},{"name":"OR449723","node_attrs":{"div":2,"accession":"OR449723","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR449723/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI1008"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T168120-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}}]},{"name":"NODE_0000057","node_attrs":{"div":5,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C28104T","C28175T","G112246A","C125152T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C162012T"],"OPG044":["S5L"],"OPG131":["D103N"]},"labels":{"aa":"OPG044: S5L; OPG131: D103N"}},"children":[{"name":"OP555647","node_attrs":{"div":7,"accession":"OP555647","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555647/2022-09-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-05"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0576/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C46132T","A153083G"],"OPG065":["D118N"],"OPG180":["K131R"]},"labels":{"aa":"OPG065: D118N; OPG180: K131R"}}},{"name":"OP555634","node_attrs":{"div":5,"accession":"OP555634","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555634/2022-09-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-05"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0563/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000058","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C181216T","-196615A"]}},"children":[{"name":"OP555629","node_attrs":{"div":1,"accession":"OP555629","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555629/2022-08-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-30"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0558/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP555576","node_attrs":{"div":1,"accession":"OP555576","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555576/2022-08-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-12"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0502/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000059","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G15683A","C104028T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G184416A","-196615A"],"OPG123":["G348E"],"OPG210":["D1021N"]},"labels":{"aa":"OPG123: G348E; OPG210: D1021N"}},"children":[{"name":"OP920696","node_attrs":{"div":3,"accession":"OP920696","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"strain_display":{"value":"USA/OP920696/2022-11-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-11-05"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00358/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OQ644780","node_attrs":{"div":3,"accession":"OQ644780","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ644780/2022-11-18"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-11-18"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00474/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000060","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G187156A"]}},"children":[{"name":"OQ451895","node_attrs":{"div":1,"accession":"OQ451895","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ451895/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI710"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OQ644785","node_attrs":{"div":8,"accession":"OQ644785","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ644785/2022-12-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-12-01"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00479/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A713-","G714-","T715-","C3375T","C35216T","C105831T","G111029A","G134403A","C140075T","G158161A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C183982T","G193835A","C196668-","T196669-","T196670-"],"OPG054":["D261N"],"OPG159":["S103F"],"OPG210":["T876M"]},"labels":{"aa":"OPG054: D261N; OPG159: S103F; OPG210: T876M"}}}]},{"name":"NODE_0000061","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G174678A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OQ348870","node_attrs":{"div":1,"accession":"OQ348870","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"strain_display":{"value":"USA/OQ348870/2022-06-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2022-06-30"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000123/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","T6976-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR035644","node_attrs":{"div":1,"accession":"OR035644","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035644/2022-07-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-27"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_38"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000062","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C36405T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG055":["A227T"]},"labels":{"aa":"OPG055: A227T"}},"children":[{"name":"OQ503798","node_attrs":{"div":3,"accession":"OQ503798","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ503798/2023-01-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-01-03"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00410/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","G5416A","G102694A","C191794T"]}}},{"name":"OR353573","node_attrs":{"div":2,"accession":"OR353573","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"strain_display":{"value":"USA/OR353573/2022-08-29"},"host":{"value":"Homo sapiens"},"institution":{"value":"Minnesota Department of Health, Public Health Laboratory"},"date":{"value":"2022-08-29"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MN-MDH-MPXV_0063"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","C54716T","C196745-","C196746-","A196747-"],"OPG072":["P83S"]},"labels":{"aa":"OPG072: P83S"}}}]},{"name":"NODE_0000063","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C12298T","C32853T","G35385A","C169036T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG049":["G100E"]},"labels":{"aa":"OPG049: G100E"}},"children":[{"name":"OR035730","node_attrs":{"div":4,"accession":"OR035730","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035730/2022-09-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-09-20"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_124"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T196712-","A196713-","T196714-"]}}},{"name":"OR035727","node_attrs":{"div":4,"accession":"OR035727","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035727/2022-10-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_121"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000064","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C111391T","C119654T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","C152191T","A173314-","T173315-","A173316-","T173317-","C176178T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-"],"OPG130":["C171Y"],"OPG137":["S18L"],"OPG205":["H175Y"]},"labels":{"aa":"OPG130: C171Y; OPG137: S18L; OPG205: H175Y"}},"children":[{"name":"OQ973327","node_attrs":{"div":4,"accession":"OQ973327","author":{"author":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L.","value":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L."},"strain_display":{"value":"Belgium/OQ973327/2022-09-06"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-09-06"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"case1_skin"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G173595-","G173596-","T173597-","T173598-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","A180535-","A180536-","T180537-","A180538-","G180539-","C180540-","G180541-","T180542-","A180543-","T180544-","C180545-","T180546-","T180547-","A180548-"]}}},{"name":"OQ973326","node_attrs":{"div":4,"accession":"OQ973326","author":{"author":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L.","value":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L."},"strain_display":{"value":"Belgium/OQ973326/2022-09-01"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"case1_air"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G2615-","A2616-","T2617-","A2618-","G2619-","A2620-","C2621-","A2622-","A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","T2653-","T2654-","T2655-","A2656-","C2657-","A2658-","C2659-","T2660-","T2661-","A194549-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","A196613-","A196614-"],"OPG002":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-"],"OPG002_dup":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-"]},"labels":{"aa":"OPG002: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-; OPG002_dup: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-"}}}]},{"name":"NODE_0000065","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C71193T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}},"children":[{"name":"OQ918696","node_attrs":{"div":6,"accession":"OQ918696","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ918696/2023-03-11"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-03-11"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00485/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G30285A","G37487A","G119839A","C161690T","C177865T","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T179244-"],"OPG047":["P304S"],"OPG137":["E80K"],"OPG188":["S32F"],"OPG205":["S737F"]},"labels":{"aa":"OPG047: P304S; OPG137: E80K; OPG188: S32F; OPG205: S737F"}}},{"name":"OR759217","node_attrs":{"div":2,"accession":"OR759217","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759217/2022-07-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-07-01"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL129/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C5169T","G192041A"],"OPG015":["D330N"],"OPG015_dup":["D330N"]},"labels":{"aa":"OPG015: D330N; OPG015_dup: D330N"}}}]},{"name":"NODE_0000066","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C28887T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG045":["E126K"]},"labels":{"aa":"OPG045: E126K"}},"children":[{"name":"OX336038","node_attrs":{"div":1,"accession":"OX336038","strain_display":{"value":"Slovakia/OX336038/2022-08-31"},"host":{"value":"Homo sapiens"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"date":{"value":"2022-08-31"},"lineage":{"value":"B.1"},"country":{"value":"Slovakia"},"strain":{"value":"RNA"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OX291694","node_attrs":{"div":5,"accession":"OX291694","strain_display":{"value":"Slovakia/OX291694/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1"},"country":{"value":"Slovakia"},"strain":{"value":"RNA"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C15311T","C54262T","G81015T","G141131A"],"OPG104":["T2K"]},"labels":{"aa":"OPG104: T2K"}}}]},{"name":"NODE_0000067","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G64522A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"]}},"children":[{"name":"OX297403","node_attrs":{"div":1,"accession":"OX297403","strain_display":{"value":"Slovakia/OX297403/2022-08-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"date":{"value":"2022-08-09"},"lineage":{"value":"B.1"},"country":{"value":"Slovakia"},"strain":{"value":"RNA"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-"]}}},{"name":"OX261749","node_attrs":{"div":1,"accession":"OX261749","strain_display":{"value":"Slovakia/OX261749/2022-07-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"date":{"value":"2022-07-20"},"lineage":{"value":"B.1"},"country":{"value":"Slovakia"},"strain":{"value":"RNA"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-"]}}}]},{"name":"NODE_0000068","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G57076A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG074":["S17L"]},"labels":{"aa":"OPG074: S17L"}},"children":[{"name":"OX291435","node_attrs":{"div":1,"accession":"OX291435","strain_display":{"value":"Slovakia/OX291435/2022-07-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"date":{"value":"2022-07-25"},"lineage":{"value":"B.1"},"country":{"value":"Slovakia"},"strain":{"value":"RNA"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T164536-","T164537-","G164538-","A164539-","A164540-","A164541-","A164542-","T164543-","T164544-","A164545-","T164546-","G164547-","A164548-","T164549-","A164550-","C164551-","C164552-","A164553-","T164554-","C164555-","T164556-","A173314-","T173315-","A173316-","T173317-"],"OPG189":["L402-","K403-","I404-","M405-","I406-","P407-","S408-"]},"labels":{"aa":"OPG189: L402-, K403-, I404-, M405-, I406-, P407-, S408-"}}},{"name":"OX291424","node_attrs":{"div":1,"accession":"OX291424","strain_display":{"value":"Slovakia/OX291424/2022-07-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"date":{"value":"2022-07-25"},"lineage":{"value":"B.1"},"country":{"value":"Slovakia"},"strain":{"value":"RNA"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000069","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C67289T"],"OPG085":["E415K"]},"labels":{"aa":"OPG085: E415K"}},"children":[{"name":"OR759214","node_attrs":{"div":4,"accession":"OR759214","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759214/2022-07-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-07-01"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL126/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C25172T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G164327A","G164910A","A196614-"],"OPG040":["D103N"],"OPG189":["G332E"]},"labels":{"aa":"OPG040: D103N; OPG189: G332E"}}},{"name":"OR500079","node_attrs":{"div":6,"accession":"OR500079","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"strain_display":{"value":"Romania/OR500079/2022-08-04"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"date":{"value":"2022-08-04"},"lineage":{"value":"B.1"},"country":{"value":"Romania"},"strain":{"value":"hMpxV/Romania/B-16/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A31817T","G74360A","G97717T","C133109A","C166374G","T166375G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG094":["R194H"],"OPG117":["E557*"],"OPG191":["L72G"]},"labels":{"aa":"OPG094: R194H; OPG117: E557*; OPG191: L72G"}}}]},{"name":"NODE_0000070","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C187154T"]}},"children":[{"name":"ON568298","node_attrs":{"div":1,"accession":"ON568298","author":{"author":"Antwerpen,M.H.,Lang,D.,Zange,S.,Walter,M.C.,Woelfel,R.","value":"Antwerpen,M.H.,Lang,D.,Zange,S.,Walter,M.C.,Woelfel,R."},"strain_display":{"value":"Germany/ON568298/2022-05-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"Microbiol Genomics & Bioinformatics, Bundeswehr Institute of Microbiology, Germany"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV-BY-IMB25241"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A"]}}},{"name":"ON927243","node_attrs":{"div":1,"accession":"ON927243","author":{"author":"Palomino-Cabrera,R.,Penas-Utrilla,D.,Buenestado-Serrano,S.,Perez-Lago,L.,Herranz Martin,M.,Veintimilla,C.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Palomino-Cabrera,R.,Penas-Utrilla,D.,Buenestado-Serrano,S.,Perez-Lago,L.,Herranz Martin,M.,Veintimilla,C.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"strain_display":{"value":"Spain/ON927243/2022-06-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"HGUGM, Microbial Genomics"},"date":{"value":"2022-06-21"},"lineage":{"value":"B.1"},"country":{"value":"Spain"},"strain":{"value":"MpxV/Spain/MD-HGUGM-6642566/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-"]}}},{"name":"OR086984","node_attrs":{"div":2,"accession":"OR086984","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR086984/2022-07-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-27"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_175/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G152001A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196748-","T196749-","C196750-"],"OPG178":["D165N"]},"labels":{"aa":"OPG178: D165N"}}}]},{"name":"NODE_0000071","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133102-","A140152-","A140153-","T140154-","A140155-","T168120C","-179207A"],"OPG159":["N130-"],"OPG193":["F263L"]},"labels":{"aa":"OPG159: N130-; OPG193: F263L"}},"children":[{"name":"OP144216","node_attrs":{"div":1,"accession":"OP144216","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P."},"strain_display":{"value":"Belgium/OP144216/2022-05-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-05-30"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/ITM_pt_07/Belgium/30-May-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A133165-","A133166-","T133167-","C133168-","T133169-","T133170-","T133171-","C133172-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T140113-","A140114-","T140115-","A140116-","A140117-","T140122-","A140123-","T140124-","A140125-","A140126-","C140127-","A140128-","A140129-","T140130-","T140131-","A140132-","T140133-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","A140143-","A140144-","T140145-","T140146-","G140147-","T140148-","T140149-","A140150-","T140151-","-179240T","-179241A","-179242T","-179243A"],"OPG159":["Y116-","N117-","Y119-","N120-","N121-","Y122-","N123-","N124-","Y125-","N126-","C127-","Y128-","N129-"]},"labels":{"aa":"OPG159: Y116-, N117-, Y119-, N120-, N121-, Y122-, N123-, N124-, Y125-, N126-, C127-, Y128-, N129-"}}},{"name":"OP144215","node_attrs":{"div":1,"accession":"OP144215","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P."},"strain_display":{"value":"Belgium/OP144215/2022-05-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-05-30"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/ITM_pt_05/Belgium/30-May-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-140152A","-140153A","-140154T","-140155A","T179244-","C179245-","G179246-","T179247-","T179248-"],"OPG159":["-130N"]},"labels":{"aa":"OPG159: -130N"}}},{"name":"OP144213","node_attrs":{"div":1,"accession":"OP144213","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P."},"strain_display":{"value":"Belgium/OP144213/2022-06-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-06-16"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/ITM_pt_24/Belgium/16-Jun-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A140156-","T140157-","T140158-","A140159-","T140160-","A140161-","A140162-","T140163-","A173367-","G173368-","A173369-","A173370-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","-196615A","-196616A"],"OPG159":["Y131-","N132-","C133-"]},"labels":{"aa":"OPG159: Y131-, N132-, C133-"}}}]},{"name":"NODE_0000072","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G169928A"],"OPG197":["D87N"]},"labels":{"aa":"OPG197: D87N"}},"children":[{"name":"OR449701","node_attrs":{"div":2,"accession":"OR449701","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR449701/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI987"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G58518A","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"NODE_0000073","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G10118A","C15004T"],"OPG021":["E178K"]},"labels":{"aa":"OPG021: E178K"}},"children":[{"name":"ON983165","node_attrs":{"div":5,"accession":"ON983165","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"strain_display":{"value":"Canada/ON983165/2022-06-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-14"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-3686/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G16819A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A163211-","A163212-","C163213-","T163214-","C180825T"],"OPG029":["S84L"],"OPG209":["S103F"]},"labels":{"aa":"OPG029: S84L; OPG209: S103F"}}},{"name":"ON751962","node_attrs":{"div":3,"accession":"ON751962","author":{"author":"Claro,I.M.,de Lima,E.L.,Romano,C.M.,Candido,D.S.,Lindoso,J.A.L.,Barra,L.A.C.,Borges,L.M.S.,Medeiros,L.A.,Tomishige,M.Y.S.,Ramundo,M.S.,Moutinho,T.,da Silva,A.J.D.,Rodrigues,C.C.M.,de Azevedo,L.C.F.,Villas-Boas,L.S.,da Silva,C.A.M.,Coletti,T.M.,O'Toole,A.,Quick,J.,Loman,N.,Rambaut,A.,Faria,N.R.,Figueiredo-Mello,C.,Sabino,E.C.","value":"Claro,I.M.,de Lima,E.L.,Romano,C.M.,Candido,D.S.,Lindoso,J.A.L.,Barra,L.A.C.,Borges,L.M.S.,Medeiros,L.A.,Tomishige,M.Y.S.,Ramundo,M.S.,Moutinho,T.,da Silva,A.J.D.,Rodrigues,C.C.M.,de Azevedo,L.C.F.,Villas-Boas,L.S.,da Silva,C.A.M.,Coletti,T.M.,O'Toole,A.,Quick,J.,Loman,N.,Rambaut,A.,Faria,N.R.,Figueiredo-Mello,C.,Sabino,E.C."},"strain_display":{"value":"Brazil/ON751962/2022-06-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"Imperial College London, School of Public Health"},"date":{"value":"2022-06-07"},"lineage":{"value":"B.1"},"country":{"value":"Brazil"},"strain":{"value":"Monkeypox/BR0001/2022"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","G173575-","A173576-","G173577-","A173578-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]}]},{"name":"NODE_0000074","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C49892T"]}},"children":[{"name":"ON803439","node_attrs":{"div":6,"accession":"ON803439","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/ON803439/2022-05-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-20"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-2899/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G14611A","C19894T","C41219T","G52752A","C89344T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG034":["D38N"],"OPG061":["M222I"],"OPG109":["R35Q"]},"labels":{"aa":"OPG034: D38N; OPG061: M222I; OPG109: R35Q"}}},{"name":"ON619837","node_attrs":{"div":2,"accession":"ON619837","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/ON619837/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Research & Evaluation, UKHSA, UK"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_3"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C153993T","-179174T","-179176A","-179177T","-179178A","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OP205095","node_attrs":{"div":2,"accession":"OP205095","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205095/2022-06-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-13"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000107"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","A56110G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG074":["L339S"]},"labels":{"aa":"OPG074: L339S"}}}]},{"name":"NODE_0000075","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C130606T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}},"children":[{"name":"OP205113","node_attrs":{"div":3,"accession":"OP205113","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205113/2022-06-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-16"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000150"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G89296T","G165465A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG109":["T51K"],"OPG190":["G115E"]},"labels":{"aa":"OPG109: T51K; OPG190: G115E"}}},{"name":"NODE_0000076","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C45203T","C88917T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}},"children":[{"name":"OQ627927","node_attrs":{"div":3,"accession":"OQ627927","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"strain_display":{"value":"Italy/OQ627927/2022-08-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"date":{"value":"2022-08-16"},"lineage":{"value":"B.1"},"country":{"value":"Italy"},"strain":{"value":"INMI-18982022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OQ570420","node_attrs":{"div":3,"accession":"OQ570420","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"strain_display":{"value":"Italy/OQ570420/2022-08-11"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"date":{"value":"2022-08-11"},"lineage":{"value":"B.1"},"country":{"value":"Italy"},"strain":{"value":"INMI-14732022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000077","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A34503C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG053":["F63C"]},"labels":{"aa":"OPG053: F63C"}},"children":[{"name":"OP440587","node_attrs":{"div":10,"accession":"OP440587","author":{"author":"Hemarajata,P.,Green,N.M.","value":"Hemarajata,P.,Green,N.M."},"strain_display":{"value":"USA/OP440587/2022-07-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-07-27"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00018/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G13224A","A13229G","A52225G","C103266T","T130733C","G146714A","G153910A","T156800G","G156802T","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG024":["S2L"],"OPG123":["R602K"],"OPG151":["C604R"],"OPG170":["A22V"],"OPG180":["E407K"]},"labels":{"aa":"OPG024: S2L; OPG123: R602K; OPG151: C604R; OPG170: A22V; OPG180: E407K"}}},{"name":"OP414319","node_attrs":{"div":1,"accession":"OP414319","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP414319/2022-06-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-06-14"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0280/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T136538C","T136547C"],"OPG153":["D374G","D377G"]},"labels":{"aa":"OPG153: D374G, D377G"}}},{"name":"OP414320","node_attrs":{"div":2,"accession":"OP414320","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP414320/2022-06-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-06-09"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0281/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","A138834C"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-"}}}]},{"name":"NODE_0000078","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C77462T"],"OPG098":["S188F"]},"labels":{"aa":"OPG098: S188F"}},"children":[{"name":"OP378693","node_attrs":{"div":1,"accession":"OP378693","author":{"author":"Gigante,C.M.,Hauser,J.R.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y.","value":"Gigante,C.M.,Hauser,J.R.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y."},"strain_display":{"value":"USA/OP378693/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_DC0009"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T4775-","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OR759213","node_attrs":{"div":3,"accession":"OR759213","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759213/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL125/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C804T","G41373A","C103427T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G196406A"],"OPG061":["S171L"]},"labels":{"aa":"OPG061: S171L"}}},{"name":"OR759186","node_attrs":{"div":4,"accession":"OR759186","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759186/2022-09-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL098/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C111164T","A143676G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C152385T"],"OPG130":["E247K"],"OPG165":["N54S"]},"labels":{"aa":"OPG130: E247K; OPG165: N54S"}}}]},{"name":"NODE_0000079","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C136572T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G158190A","-196615A","-196616T"],"OPG153":["E366K"]},"labels":{"aa":"OPG153: E366K"}},"children":[{"name":"OP555527","node_attrs":{"div":1,"accession":"OP555527","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555527/2022-08-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-03"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0446/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T"]}}},{"name":"OP555658","node_attrs":{"div":2,"accession":"OP555658","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555658/2022-09-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-13"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0591/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","C138333T"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OQ773483","node_attrs":{"div":1,"accession":"OQ773483","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ773483/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI864"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-"]}}}]},{"name":"NODE_0000080","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A87268G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG109":["V727A"]},"labels":{"aa":"OPG109: V727A"}},"children":[{"name":"OP524000","node_attrs":{"div":1,"accession":"OP524000","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP524000/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI398"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000081","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G84579A","G115865A"],"OPG105":["D1152N"],"OPG134":["R39K"]},"labels":{"aa":"OPG105: D1152N; OPG134: R39K"}},"children":[{"name":"OP588281","node_attrs":{"div":3,"accession":"OP588281","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP588281/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI418"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP689663","node_attrs":{"div":3,"accession":"OP689663","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP689663/2022-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI510"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000082","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C84063T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}},"children":[{"name":"OP484676","node_attrs":{"div":1,"accession":"OP484676","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP484676/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI355"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000083","node_attrs":{"div":7,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C14098T","G111029A","G142493A","G151324A","C170573T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C187332T","C196696-","G196697-","A196698-"],"OPG163":["D98N"],"OPG198":["S179L"]},"labels":{"aa":"OPG163: D98N; OPG198: S179L"}},"children":[{"name":"OQ331003","node_attrs":{"div":9,"accession":"OQ331003","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ331003/2022-12-06"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-12-06"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00392/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G97749A","G188726A"]}}},{"name":"OR499960","node_attrs":{"div":13,"accession":"OR499960","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499960/2023-03-15"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-03-15"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00503/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G6746A","C39266T","C63819T","G106927A","G138862A","G169213A"],"OPG083":["V300I"],"OPG125":["T243M"],"OPG156":["S183F"]},"labels":{"aa":"OPG083: V300I; OPG125: T243M; OPG156: S183F"}}}]}]},{"name":"NODE_0000084","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G184141A"],"OPG210":["G929D"]},"labels":{"aa":"OPG210: G929D"}},"children":[{"name":"OP615325","node_attrs":{"div":2,"accession":"OP615325","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP615325/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI449"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","G183382A"],"OPG210":["R676Q"]},"labels":{"aa":"OPG210: R676Q"}}},{"name":"NODE_0000085","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G67955A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG085":["P193S"]},"labels":{"aa":"OPG085: P193S"}},"children":[{"name":"OX291780","node_attrs":{"div":2,"accession":"OX291780","strain_display":{"value":"Slovakia/OX291780/2022-07-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"date":{"value":"2022-07-25"},"lineage":{"value":"B.1"},"country":{"value":"Slovakia"},"strain":{"value":"RNA"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A173316-","T173317-"]}}},{"name":"OX291676","node_attrs":{"div":3,"accession":"OX291676","strain_display":{"value":"Slovakia/OX291676/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1"},"country":{"value":"Slovakia"},"strain":{"value":"RNA"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G14590A","T133102-"]}}}]}]},{"name":"NODE_0000086","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C93755T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}},"children":[{"name":"OR095055","node_attrs":{"div":4,"accession":"OR095055","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR095055/2022-08-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-12"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_237/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C7851T","C134847T","G143463A","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG019":["S91L"]},"labels":{"aa":"OPG019: S91L"}}},{"name":"NODE_0000087","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C55859T"],"OPG074":["V423I"]},"labels":{"aa":"OPG074: V423I"}},"children":[{"name":"OP555660","node_attrs":{"div":2,"accession":"OP555660","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555660/2022-09-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-14"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0593/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OQ451901","node_attrs":{"div":6,"accession":"OQ451901","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ451901/2022-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI716"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C2315T","G21250A","G40586A","G146821A","G160267A","G194895A"],"OPG002":["G146E"],"OPG002_dup":["G146E"],"OPG037":["S395F"]},"labels":{"aa":"OPG002: G146E; OPG002_dup: G146E; OPG037: S395F"}}}]}]},{"name":"NODE_0000088","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C21998T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG037":["D146N"]},"labels":{"aa":"OPG037: D146N"}},"children":[{"name":"OP555559","node_attrs":{"div":2,"accession":"OP555559","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555559/2022-08-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-09"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0480/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G17432-","G71712A","-179244T","-179245C","-179246G","-179247T","-179248T","-179249A","-179250T","-179251T","-179252G","-179253T","-179254T","-179255T","-179256G","-179257G","-179258T","-179259C","-179260T","-179261A","-179262T"]}}},{"name":"OQ773473","node_attrs":{"div":1,"accession":"OQ773473","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ773473/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI854"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G150551-","G150565-","A173316-","T173317-"]}}},{"name":"OR449718","node_attrs":{"div":1,"accession":"OR449718","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR449718/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI1004"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T168120-","G179263-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}}]},{"name":"NODE_0000089","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G16956A","C94427T","G141759A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","C184829T"],"OPG114":["E81K"]},"labels":{"aa":"OPG114: E81K"}},"children":[{"name":"OP837478","node_attrs":{"div":4,"accession":"OP837478","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"strain_display":{"value":"Colombia/OP837478/2022-09-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-09-20"},"lineage":{"value":"B.1"},"country":{"value":"Colombia"},"strain":{"value":"DC_INS_MPX_1011_L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000090","node_attrs":{"div":6,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C14091T","G56721A","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","A196614-"],"OPG025":["E393K"]},"labels":{"aa":"OPG025: E393K"}},"children":[{"name":"OQ427117","node_attrs":{"div":6,"accession":"OQ427117","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"strain_display":{"value":"USA/OQ427117/2022-11-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-11-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_NY0042"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133102-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-"]}}},{"name":"OR464192","node_attrs":{"div":6,"accession":"OR464192","author":{"author":"Gigante,C.,Pettit,D.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Deutsch-Feldman,M.,Li,Y.","value":"Gigante,C.,Pettit,D.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Deutsch-Feldman,M.,Li,Y."},"strain_display":{"value":"USA/OR464192/2022-12-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-12-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_NC0016"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000091","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G21655A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG037":["S260L"]},"labels":{"aa":"OPG037: S260L"}},"children":[{"name":"OP837354","node_attrs":{"div":1,"accession":"OP837354","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP837354/2022-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI592"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP764629","node_attrs":{"div":1,"accession":"OP764629","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP764629/2022-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI571"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OQ451900","node_attrs":{"div":1,"accession":"OQ451900","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ451900/2022-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI715"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T"]}}}]},{"name":"NODE_0000092","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G162623A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG188":["R343K"]},"labels":{"aa":"OPG188: R343K"}},"children":[{"name":"OR086971","node_attrs":{"div":2,"accession":"OR086971","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR086971/2022-07-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-27"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_162/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C127530T"],"OPG149":["S112L"]},"labels":{"aa":"OPG149: S112L"}}},{"name":"NODE_0000093","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C110147T"]}},"children":[{"name":"OR035731","node_attrs":{"div":3,"accession":"OR035731","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035731/2022-09-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-09-20"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_125"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G61361A"]}}},{"name":"OR035708","node_attrs":{"div":3,"accession":"OR035708","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035708/2022-10-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_102"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C60081T","T196712-","A196713-","T196714-"]}}}]}]},{"name":"NODE_0000094","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133100-","T133101-","T133102-","C147965T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG172":["S180F"]},"labels":{"aa":"OPG172: S180F"}},"children":[{"name":"OR095059","node_attrs":{"div":1,"accession":"OR095059","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR095059/2022-08-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-12"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_241/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T196852-","G196853-","T196854-"]}}},{"name":"NODE_0000095","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C28168T","T133097-","T133098-","T133099-","A173314-","T173315-","A173316-","T173317-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","C179470T","A196614-"],"OPG208":["P69S"]},"labels":{"aa":"OPG208: P69S"}},"children":[{"name":"OQ973329","node_attrs":{"div":3,"accession":"OQ973329","author":{"author":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L.","value":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L."},"strain_display":{"value":"Belgium/OQ973329/2022-09-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"case6_skin"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C173474-","G173475-","A173476-","C173477-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","A180535-","A180536-","T180537-","A180538-","G180539-","C180540-","G180541-","T180542-","A180543-","T180544-","C180545-","T180546-","T180547-","A180548-"]}}},{"name":"OQ973328","node_attrs":{"div":3,"accession":"OQ973328","author":{"author":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L.","value":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L."},"strain_display":{"value":"Belgium/OQ973328/2022-09-01"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"case6_air"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G2615-","A2616-","T2617-","A2618-","G2619-","A2620-","C2621-","A2622-","A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","T2653-","T2654-","T2655-","A2656-","C2657-","A2658-","C2659-","T2660-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","C194595-"],"OPG002":["C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-"],"OPG002_dup":["C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-"]},"labels":{"aa":"OPG002: C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-; OPG002_dup: C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-"}}}]}]},{"name":"NODE_0000096","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","A41654-","A41655-","T41656-","A41657-","C41658-","T41659-","A41660-","A41661-","T41662-","T41663-","T41664-","G41665-","T41666-","T41667-","T41668-","T41669-","A41670-","C41671-","T41672-","C41673-","T41674-","A41675-","T41676-","A41677-","C118161T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG061":["R71-","V72-","K73-","Q74-","I75-","S76-","I77-","S78-"],"OPG136":["R476Q"]},"labels":{"aa":"OPG061: R71-, V72-, K73-, Q74-, I75-, S76-, I77-, S78-; OPG136: R476Q"}},"children":[{"name":"OR264423","node_attrs":{"div":1,"accession":"OR264423","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264423/2022-07-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-13"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"46_C"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR264422","node_attrs":{"div":2,"accession":"OR264422","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264422/2022-07-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-13"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"46_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T607-","C66963T","A196615-"]}}},{"name":"OR264421","node_attrs":{"div":1,"accession":"OR264421","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264421/2022-07-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-13"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"46_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000097","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C30283T"]}},"children":[{"name":"NODE_0000098","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G153873A","C165782T"],"OPG190":["P221S"]},"labels":{"aa":"OPG190: P221S"}},"children":[{"name":"ON959164","node_attrs":{"div":3,"accession":"ON959164","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/ON959164/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI150"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"ON853676","node_attrs":{"div":3,"accession":"ON853676","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/ON853676/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI098"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000099","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C70780T","T133101-","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}},"children":[{"name":"OR264398","node_attrs":{"div":5,"accession":"OR264398","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264398/2022-06-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-06-30"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"34_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C37054T","-133101T","-133102T","G179589A","G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N"}}},{"name":"OR086952","node_attrs":{"div":2,"accession":"OR086952","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR086952/2022-07-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_143/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]}]},{"name":"NODE_0000100","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G106113A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C189810T"]}},"children":[{"name":"OP539898","node_attrs":{"div":2,"accession":"OP539898","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OP539898/2022-08-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-08-30"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00113/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000101","node_attrs":{"div":5,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G66587A","G143857A","C144237T","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG165":["S241L"]},"labels":{"aa":"OPG165: S241L"}},"children":[{"name":"OQ918700","node_attrs":{"div":5,"accession":"OQ918700","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ918700/2023-02-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-02-20"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00489/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OQ918699","node_attrs":{"div":5,"accession":"OQ918699","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ918699/2023-02-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-02-20"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00488/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","-179176A","-179177T","-179178A"]}}},{"name":"OQ918698","node_attrs":{"div":5,"accession":"OQ918698","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ918698/2023-02-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-02-20"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00487/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179082C","-179083A","-179084T","-179085T","-179086A","-179087T","-179088A","-179089T","-179090A","-179091C","-179092A","-179093T","-179094T","-179095A","-179096T","-179097A","-179098T","-179099A","-179100C","-179101A","-179102T","-179103T","-179104A","-179105T","-179106A","-179107T","-179108A","-179109C","-179110A","-179111T","-179112T","-179113A","-179114T","-179115A","-179116T","-179117A","-179118C","-179119A","-179120T","-179121T","-179122A","-179123T","-179124A","-179125T","-179126A","-179127C","-179128A","-179129T","-179130T","-179131A","-179132T","-179133A","-179134T","-179135A","-179136C","-179137A","-179138T","-179139T","-179140A","-179141T","-179142A","-179143T","-179144A","-179145C","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-"]}}}]}]},{"name":"NODE_0000102","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G2146A","C39044T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T187876C","C195064T"]}},"children":[{"name":"OQ503829","node_attrs":{"div":6,"accession":"OQ503829","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ503829/2023-01-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-01-09"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00406/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C2749T","G112552A","C167231T","G194461A"],"OPG002":["M1I"],"OPG002_dup":["M1I"],"OPG132":["S330L"]},"labels":{"aa":"OPG002: M1I; OPG002_dup: M1I; OPG132: S330L"}}},{"name":"OQ503832","node_attrs":{"div":3,"accession":"OQ503832","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ503832/2023-01-17"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-01-17"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00409/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000103","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A24345G","T170904-"]}},"children":[{"name":"OQ644777","node_attrs":{"div":4,"accession":"OQ644777","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ644777/2023-02-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-02-13"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00471/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ644776","node_attrs":{"div":4,"accession":"OQ644776","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ644776/2023-02-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-02-13"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00470/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000104","node_attrs":{"div":1,"lineage":{"value":"B.1.13"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G175093A"],"OPG204":["D188N"]},"labels":{"aa":"OPG204: D188N","clade":"B.1.13"}},"children":[{"name":"OP536663","node_attrs":{"div":3,"accession":"OP536663","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"strain_display":{"value":"USA/OP536663/2022-08-04"},"host":{"value":"Homo sapiens"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"date":{"value":"2022-08-04"},"lineage":{"value":"B.1.13"},"country":{"value":"USA"},"strain":{"value":"MPXV-USA-IL-IDPH-002"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G119424A","G125452A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG136":["S55L"],"OPG146":["S63L"]},"labels":{"aa":"OPG136: S55L; OPG146: S63L"}}},{"name":"OP748960","node_attrs":{"div":6,"accession":"OP748960","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OP748960/2022-07-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-07-20"},"lineage":{"value":"B.1.13"},"country":{"value":"USA"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00274/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C25269T","C55472T","G55632A","G137585A","C146816T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G167713A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG074":["D552N"],"OPG153":["S28F"],"OPG193":["R127K"]},"labels":{"aa":"OPG074: D552N; OPG153: S28F; OPG193: R127K"}}},{"name":"NODE_0000105","node_attrs":{"div":2,"lineage":{"value":"B.1.13"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C132520T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP257254","node_attrs":{"div":2,"accession":"OP257254","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OP257254/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.13"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/OH-UW-073812/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP536666","node_attrs":{"div":4,"accession":"OP536666","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"strain_display":{"value":"USA/OP536666/2022-06-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"date":{"value":"2022-06-30"},"lineage":{"value":"B.1.13"},"country":{"value":"USA"},"strain":{"value":"MPXV-USA-IL-IDPH-005"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G165086A","C169529T","-196615A","-196616A","-196617A"]}}},{"name":"OR160418","node_attrs":{"div":9,"accession":"OR160418","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR160418/2023-05-10"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-05-10"},"lineage":{"value":"B.1.13"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-052-0034/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C27520T","G58883A","G99832A","G102186A","G129583A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G171410A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C182950T"],"OPG043":["A146T"],"OPG118":["D463N"],"OPG121":["E133K"],"OPG210":["S532L"]},"labels":{"aa":"OPG043: A146T; OPG118: D463N; OPG121: E133K; OPG210: S532L"}}}]}]},{"name":"NODE_0000106","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C156205T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}},"children":[{"name":"OP920700","node_attrs":{"div":1,"accession":"OP920700","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"strain_display":{"value":"USA/OP920700/2022-10-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00362/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OQ330974","node_attrs":{"div":1,"accession":"OQ330974","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ330974/2022-12-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-12-23"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00395/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OQ503750","node_attrs":{"div":1,"accession":"OQ503750","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OQ503750/2022-11-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-11-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-111475/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000107","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C53342T"],"OPG071":["R366K"]},"labels":{"aa":"OPG071: R366K"}},"children":[{"name":"OP748965","node_attrs":{"div":2,"accession":"OP748965","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OP748965/2022-10-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-10-20"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00279/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OQ427135","node_attrs":{"div":3,"accession":"OQ427135","author":{"author":"Gigante,C.,Steidley,B.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Davizon,E.,Li,Y.","value":"Gigante,C.,Steidley,B.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Davizon,E.,Li,Y."},"strain_display":{"value":"USA/OQ427135/2022-11-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-11-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_CO0004"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G120238A","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","T136555-","A136556-","T136557-","G136558-","A136559-","T136560-","A136561-","T136562-","C136563-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG137":["E213K"],"OPG153":["I370-","I371-","D372-","D373-","D374-","D375-","D376-"]},"labels":{"aa":"OPG137: E213K; OPG153: I370-, I371-, D372-, D373-, D374-, D375-, D376-"}}}]}]},{"name":"NODE_0000108","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C34784T","C101418T"],"OPG054":["D405N"],"OPG120":["D111N"]},"labels":{"aa":"OPG054: D405N; OPG120: D111N"}},"children":[{"name":"OR095023","node_attrs":{"div":5,"accession":"OR095023","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR095023/2022-08-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-08"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_205/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C25464T","G99233A","G156736A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG118":["R263Q"]},"labels":{"aa":"OPG118: R263Q"}}},{"name":"NODE_0000109","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G109844A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"]}},"children":[{"name":"OR743494","node_attrs":{"div":3,"accession":"OR743494","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR743494/2023-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2023-09-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1025"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR743495","node_attrs":{"div":4,"accession":"OR743495","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR743495/2023-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2023-09-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1026"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G145312A","-179194A","-179195T","C179265-","A179266-","T179267-"]}}},{"name":"NODE_0000110","node_attrs":{"div":6,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C45528T","C84767T","C170791T"],"OPG064":["R124K"]},"labels":{"aa":"OPG064: R124K"}},"children":[{"name":"OR743498","node_attrs":{"div":6,"accession":"OR743498","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR743498/2023-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2023-10-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1029"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179263G","-179264C"]}}},{"name":"OR743497","node_attrs":{"div":8,"accession":"OR743497","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR743497/2023-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2023-10-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1028"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G143777A","G175934A","-179194A","-179195T","C179265-","A179266-","T179267-"],"OPG165":["V88I"]},"labels":{"aa":"OPG165: V88I"}}}]}]}]},{"name":"NODE_0000111","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C21128T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-196615A"],"OPG037":["E436K"]},"labels":{"aa":"OPG037: E436K"}},"children":[{"name":"OR264408","node_attrs":{"div":1,"accession":"OR264408","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264408/2022-05-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"39_K"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"ON631963","node_attrs":{"div":1,"accession":"ON631963","author":{"author":"Hammerschlag,Y.,MacLeod,G.,Papadakis,G.,Adnan Sanchez,A.,Druce,J.,Savic,I.,Taiaroa,G.,Roberts,J.,Caly,L.,Williamson,D.A.,Cheng,A.C.,McMahon,J.H.","value":"Hammerschlag,Y.,MacLeod,G.,Papadakis,G.,Adnan Sanchez,A.,Druce,J.,Savic,I.,Taiaroa,G.,Roberts,J.,Caly,L.,Williamson,D.A.,Cheng,A.C.,McMahon,J.H."},"strain_display":{"value":"Australia/ON631963/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Victorian Infectious Diseases Reference Laboratory, Doherty Institute, Australia"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"MPxV/VIDRL01/2022"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C133077T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264407","node_attrs":{"div":1,"accession":"OR264407","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264407/2022-05-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"39_I"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000113","node_attrs":{"div":5,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T607-","A22452T","C66718T","C144356T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","C188683T","A196615-"],"OPG084":["S666L"]},"labels":{"aa":"OPG084: S666L"}},"children":[{"name":"OR264405","node_attrs":{"div":5,"accession":"OR264405","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264405/2022-05-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"39_G"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR264404","node_attrs":{"div":5,"accession":"OR264404","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264404/2022-05-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"39_D"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264406","node_attrs":{"div":5,"accession":"OR264406","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264406/2022-05-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"39_H"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"]}}}]}]},{"name":"NODE_0000114","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C141757T"]}},"children":[{"name":"OR126131","node_attrs":{"div":5,"accession":"OR126131","author":{"author":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C.","value":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C."},"strain_display":{"value":"Spain/OR126131/2022-09-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"Hospital Ramon y Cajal, Microbiology"},"date":{"value":"2022-09-21"},"lineage":{"value":"B.1"},"country":{"value":"Spain"},"strain":{"value":"HRYC_MPXV001"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C11749-","C34432T","C48324T","G101294A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G190695A"],"OPG016":["E96K"],"OPG053":["E87K"],"OPG120":["S152L"]},"labels":{"aa":"OPG016: E96K; OPG053: E87K; OPG120: S152L"}}},{"name":"NODE_0000115","node_attrs":{"div":3,"lineage":{"value":"B.1.18"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C43706T","T124690C"]},"labels":{"clade":"B.1.18"}},"children":[{"name":"OP628451","node_attrs":{"div":3,"accession":"OP628451","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OP628451/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.18"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-083401/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP722512","node_attrs":{"div":3,"accession":"OP722512","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OP722512/2022-10-11"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-10-11"},"lineage":{"value":"B.1.18"},"country":{"value":"USA"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00253/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ503834","node_attrs":{"div":5,"accession":"OQ503834","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ503834/2022-10-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-10-02"},"lineage":{"value":"B.1.18"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00438/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A632-","G633-","A634-","C62673T","G91477A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196643-","T196644-","G196645-"]}}},{"name":"NODE_0000116","node_attrs":{"div":5,"lineage":{"value":"B.1.18"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G67758A","C170049T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP819956","node_attrs":{"div":6,"accession":"OP819956","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"strain_display":{"value":"Colombia/OP819956/2022-10-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-10-12"},"lineage":{"value":"B.1.18"},"country":{"value":"Colombia"},"strain":{"value":"VAC_INS_MPX_0965_EL"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G28913A"],"OPG045":["S117L"]},"labels":{"aa":"OPG045: S117L"}}},{"name":"OQ148474","node_attrs":{"div":9,"accession":"OQ148474","author":{"author":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"strain_display":{"value":"Colombia/OQ148474/2022-11-15"},"host":{"value":"Homo sapiens"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"date":{"value":"2022-11-15"},"lineage":{"value":"B.1.18"},"country":{"value":"Colombia"},"strain":{"value":"LBMB-UTP_MP-025_VAC"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C128242T","G144572A","C166940T","C168829T"],"OPG150":["S155F"],"OPG166":["A59T"]},"labels":{"aa":"OPG150: S155F; OPG166: A59T"}}}]}]}]},{"name":"NODE_0000117","node_attrs":{"div":1,"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G181367A","A196614-"]},"labels":{"clade":"B.1.9"}},"children":[{"name":"ON843175","node_attrs":{"div":1,"accession":"ON843175","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/ON843175/2022-05-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-05-30"},"lineage":{"value":"B.1.9"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0043/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP693652","node_attrs":{"div":2,"accession":"OP693652","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"strain_display":{"value":"Colombia/OP693652/2022-08-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-08-16"},"lineage":{"value":"B.1.9"},"country":{"value":"Colombia"},"strain":{"value":"DC_INS_MPX_0718_L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-606T","G134122T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000118","node_attrs":{"div":2,"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G176823A"],"OPG205":["E390K"]},"labels":{"aa":"OPG205: E390K"}},"children":[{"name":"ON880538","node_attrs":{"div":3,"accession":"ON880538","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/ON880538/2022-06-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-01"},"lineage":{"value":"B.1.9"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-3336/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C32627T"]}}},{"name":"NODE_0000119","node_attrs":{"div":3,"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C34432T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG053":["E87K"]},"labels":{"aa":"OPG053: E87K"}},"children":[{"name":"OP324538","node_attrs":{"div":4,"accession":"OP324538","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP324538/2022-06-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-06-22"},"lineage":{"value":"B.1.9"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0229/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","G96524A"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG117":["R159K"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG117: R159K"}}},{"name":"NODE_0000120","node_attrs":{"div":4,"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G155157A"],"OPG181":["R249K"]},"labels":{"aa":"OPG181: R249K"}},"children":[{"name":"OP555506","node_attrs":{"div":4,"accession":"OP555506","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555506/2022-07-26"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-26"},"lineage":{"value":"B.1.9"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0413/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP555565","node_attrs":{"div":4,"accession":"OP555565","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555565/2022-08-11"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-11"},"lineage":{"value":"B.1.9"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0489/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP555571","node_attrs":{"div":4,"accession":"OP555571","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555571/2022-08-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-16"},"lineage":{"value":"B.1.9"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0497/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-606T","-196614A"]}}}]}]}]}]},{"name":"NODE_0000121","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C23567T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP415192","node_attrs":{"div":2,"accession":"OP415192","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415192/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_Qi7K5L_9000213"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C118683T"],"OPG136":["R302K"]},"labels":{"aa":"OPG136: R302K"}}},{"name":"OP536815","node_attrs":{"div":1,"accession":"OP536815","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536815/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"9000453"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OP536754","node_attrs":{"div":3,"accession":"OP536754","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536754/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"9000374"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G10337A","C36780T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG055":["D102N"]},"labels":{"aa":"OPG055: D102N"}}},{"name":"NODE_0000122","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C67289T","G67527A","G77052A"],"OPG085":["E415K"]},"labels":{"aa":"OPG085: E415K"}},"children":[{"name":"OP415257","node_attrs":{"div":4,"accession":"OP415257","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415257/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_eunRrC_9000312"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP415213","node_attrs":{"div":4,"accession":"OP415213","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415213/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_UbfBKN_9000239"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP536788","node_attrs":{"div":4,"accession":"OP536788","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536788/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"9000413"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A"]}}},{"name":"OP536787","node_attrs":{"div":4,"accession":"OP536787","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536787/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1"},"country":{"value":"United Kingdom"},"strain":{"value":"9000412"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179210T","-179211T"]}}}]}]},{"name":"NODE_0000123","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C170573T"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}},"children":[{"name":"OP605567","node_attrs":{"div":3,"accession":"OP605567","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605567/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-25-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C71938T","G73939A","T196886-","T196887-","T196888-"],"OPG092":["R337K"],"OPG094":["D54N"]},"labels":{"aa":"OPG092: R337K; OPG094: D54N"}}},{"name":"OQ451902","node_attrs":{"div":6,"accession":"OQ451902","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ451902/2022-11-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-11-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI717"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C3602T","C53342T","C124495T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159789A","G190695A","G193608A"],"OPG003":["E336K"],"OPG003_dup":["E336K"],"OPG016":["E96K"],"OPG071":["R366K"]},"labels":{"aa":"OPG003: E336K; OPG003_dup: E336K; OPG016: E96K; OPG071: R366K"}}},{"name":"OR264449","node_attrs":{"div":5,"accession":"OR264449","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264449/2022-08-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-25"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"64_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G25098A","G25300A","A28529-","A28530-","T76084-","T76085-","G105735A","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","G188839A"],"OPG040":["S60F"],"OPG044":["K147-"]},"labels":{"aa":"OPG040: S60F; OPG044: K147-"}}},{"name":"NODE_0000124","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N"}},"children":[{"name":"OR353577","node_attrs":{"div":4,"accession":"OR353577","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"strain_display":{"value":"USA/OR353577/2022-09-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Minnesota Department of Health, Public Health Laboratory"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MN-MDH-MPXV_0067"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A20156G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C188391T"]}}},{"name":"OR759146","node_attrs":{"div":4,"accession":"OR759146","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759146/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL053/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C3405T","G5375A","C191835T","G193805A"],"OPG015":["A261V"],"OPG015_dup":["A261V"]},"labels":{"aa":"OPG015: A261V; OPG015_dup: A261V"}}}]},{"name":"NODE_0000125","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C25644T","G144556A","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}},"children":[{"name":"OR264460","node_attrs":{"div":3,"accession":"OR264460","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264460/2022-07-11"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-11"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"7_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR264370","node_attrs":{"div":3,"accession":"OR264370","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264370/2022-07-11"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-11"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"18_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000126","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C156429T"]}},"children":[{"name":"NODE_0000127","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C65571T","G144988A","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP062229","node_attrs":{"div":3,"accession":"OP062229","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Jolly,G.,Griffiths,E.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Jolly,G.,Griffiths,E.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/OP062229/2022-06-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-16"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-3817/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP013006","node_attrs":{"div":3,"accession":"OP013006","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I."},"strain_display":{"value":"Canada/OP013006/2022-06-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-07"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-3542/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP279046","node_attrs":{"div":3,"accession":"OP279046","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"strain_display":{"value":"Canada/OP279046/2022-07-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-4150/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-179172C","-196615A","-196616A"]}}},{"name":"OP270027","node_attrs":{"div":4,"accession":"OP270027","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/OP270027/2022-07-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-4024/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C181455T"],"OPG210":["Q34*"]},"labels":{"aa":"OPG210: Q34*"}}}]},{"name":"NODE_0000128","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G162265A","C165278T"],"OPG188":["E224K"],"OPG190":["H53Y"]},"labels":{"aa":"OPG188: E224K; OPG190: H53Y"}},"children":[{"name":"OP019277","node_attrs":{"div":3,"accession":"OP019277","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"strain_display":{"value":"Austria/OP019277/2022-07-04"},"host":{"value":"Homo sapiens"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"date":{"value":"2022-07-04"},"lineage":{"value":"B.1"},"country":{"value":"Austria"},"strain":{"value":"hMPXV/Austria/MUW1531254/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP324457","node_attrs":{"div":4,"accession":"OP324457","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP324457/2022-07-11"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-11"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0134/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C188566T","-196615A"]}}},{"name":"OP555491","node_attrs":{"div":4,"accession":"OP555491","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555491/2022-07-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-13"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0395/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","G109695A","-196615A","-196616T"],"OPG129":["T437I"]},"labels":{"aa":"OPG129: T437I"}}},{"name":"OP555504","node_attrs":{"div":4,"accession":"OP555504","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555504/2022-07-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-21"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0411/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C139646T"],"OPG158":["E42K"]},"labels":{"aa":"OPG158: E42K"}}}]}]},{"name":"NODE_0000129","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G102694A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}},"children":[{"name":"OQ547873","node_attrs":{"div":1,"accession":"OQ547873","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"strain_display":{"value":"USA/OQ547873/2022-12-15"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2022-12-15"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000155/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T620-","T621-","T622-","T6976-","A140155T","A140156G"],"OPG159":["N130C"]},"labels":{"aa":"OPG159: N130C"}}},{"name":"OQ644787","node_attrs":{"div":3,"accession":"OQ644787","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ644787/2023-01-18"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-01-18"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00481/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C12684T","G90825A"],"OPG023":["E73K"]},"labels":{"aa":"OPG023: E73K"}}},{"name":"NODE_0000130","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G28490A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG044":["D134N"]},"labels":{"aa":"OPG044: D134N"}},"children":[{"name":"OP422341","node_attrs":{"div":2,"accession":"OP422341","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"strain_display":{"value":"Austria/OP422341/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1"},"country":{"value":"Austria"},"strain":{"value":"hMPXV/Austria/MUW1538395/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP422342","node_attrs":{"div":3,"accession":"OP422342","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"strain_display":{"value":"Austria/OP422342/2022-08-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"date":{"value":"2022-08-02"},"lineage":{"value":"B.1"},"country":{"value":"Austria"},"strain":{"value":"hMPXV/Austria/MUW1539124/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C110960T"]}}}]},{"name":"NODE_0000131","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","C179853T","-196615A"]}},"children":[{"name":"OP324496","node_attrs":{"div":4,"accession":"OP324496","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP324496/2022-06-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-06-28"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0181/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C13797T","G16389A"],"OPG025":["D491N"]},"labels":{"aa":"OPG025: D491N"}}},{"name":"OP555651","node_attrs":{"div":3,"accession":"OP555651","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555651/2022-09-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-09"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0580/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C121514T"],"OPG140":["G78E"]},"labels":{"aa":"OPG140: G78E"}}},{"name":"NODE_0000132","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G101192A"],"OPG120":["P186L"]},"labels":{"aa":"OPG120: P186L"}},"children":[{"name":"OP555639","node_attrs":{"div":3,"accession":"OP555639","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555639/2022-09-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-02"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0568/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP555638","node_attrs":{"div":3,"accession":"OP555638","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555638/2022-09-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-03"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0567/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000133","node_attrs":{"div":2,"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G12169A","G44960A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]},"labels":{"clade":"B.1.17"}},"children":[{"name":"OP442552","node_attrs":{"div":2,"accession":"OP442552","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"strain_display":{"value":"USA/OP442552/2022-07-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-07-13"},"lineage":{"value":"B.1.17"},"country":{"value":"USA"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00085/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G771-","T772-","G773-","A196789-","A196790-","T196791-"]}}},{"name":"OQ054244","node_attrs":{"div":2,"accession":"OQ054244","author":{"author":"Gigante,C.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y.","value":"Gigante,C.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y."},"strain_display":{"value":"USA/OQ054244/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.17"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_CA0029"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A173316-","T173317-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP890564","node_attrs":{"div":3,"accession":"OP890564","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OP890564/2022-11-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-11-09"},"lineage":{"value":"B.1.17"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00336/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A39482T"],"OPG057":["H238Q"]},"labels":{"aa":"OPG057: H238Q"}}},{"name":"NODE_0000134","node_attrs":{"div":3,"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C39334G"],"OPG057":["A288P"]},"labels":{"aa":"OPG057: A288P"}},"children":[{"name":"OP890574","node_attrs":{"div":4,"accession":"OP890574","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OP890574/2022-11-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-11-09"},"lineage":{"value":"B.1.17"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00317/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G178111A","A196625-","T196626-","T196627-"]}}},{"name":"OP890567","node_attrs":{"div":5,"accession":"OP890567","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OP890567/2022-11-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-11-09"},"lineage":{"value":"B.1.17"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00310/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G140635A","G164476A"],"OPG160":["S147L"],"OPG189":["E382K"]},"labels":{"aa":"OPG160: S147L; OPG189: E382K"}}}]},{"name":"NODE_0000135","node_attrs":{"div":4,"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A39395-","T39396-","T39397-","C85931T","G182189A"],"OPG057":["N267-"]},"labels":{"aa":"OPG057: N267-"}},"children":[{"name":"OQ503819","node_attrs":{"div":6,"accession":"OQ503819","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ503819/2022-12-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-12-14"},"lineage":{"value":"B.1.17"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00426/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C177509T","C177703T","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG205":["S683L"]},"labels":{"aa":"OPG205: S683L"}}},{"name":"NODE_0000136","node_attrs":{"div":5,"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G71249A"],"OPG090":["R24Q"]},"labels":{"aa":"OPG090: R24Q"}},"children":[{"name":"OQ547883","node_attrs":{"div":6,"accession":"OQ547883","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"strain_display":{"value":"USA/OQ547883/2023-01-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2023-01-02"},"lineage":{"value":"B.1.17"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000175/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A31053G"],"OPG047":["C48R"]},"labels":{"aa":"OPG047: C48R"}}},{"name":"OQ991943","node_attrs":{"div":5,"accession":"OQ991943","author":{"author":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J.","value":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J."},"strain_display":{"value":"USA/OQ991943/2023-01-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2023-01-13"},"lineage":{"value":"B.1.17"},"country":{"value":"USA"},"strain":{"value":"OQ991943"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000137","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G177009A"],"OPG205":["E452K"]},"labels":{"aa":"OPG205: E452K"}},"children":[{"name":"OP743964","node_attrs":{"div":3,"accession":"OP743964","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OP743964/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-098738/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G157078A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G187085A","-196615A"]}}},{"name":"NODE_0000138","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C17048T","G74360A","G93828A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG029":["D8N"],"OPG094":["R194H"],"OPG113":["E700K"]},"labels":{"aa":"OPG029: D8N; OPG094: R194H; OPG113: E700K"}},"children":[{"name":"OQ159028","node_attrs":{"div":5,"accession":"OQ159028","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ159028/2022-11-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-11-XX"},"lineage":{"value":"B.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI633"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C41131T"],"OPG060":["E18K"]},"labels":{"aa":"OPG060: E18K"}}},{"name":"OQ735077","node_attrs":{"div":11,"accession":"OQ735077","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OQ735077/2023-03-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-03-21"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0626/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-609T","A615-","C616-","C10929T","C22179T","G39515A","G77076A","G129659A","C129949T","G139167A","C196638-","T196639-"],"OPG023":["E658K"],"OPG151":["E246K"]},"labels":{"aa":"OPG023: E658K; OPG151: E246K"}}}]},{"name":"NODE_0000139","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C118453T","G137276A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"],"OPG136":["E379K"],"OPG153":["S131F"]},"labels":{"aa":"OPG136: E379K; OPG153: S131F"}},"children":[{"name":"OR499948","node_attrs":{"div":4,"accession":"OR499948","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499948/2023-04-10"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-04-10"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00491/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G635-","A636-","A637-","A1697-","G39327A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","T195519-"],"OPG057":["A290V"]},"labels":{"aa":"OPG057: A290V"}}},{"name":"NODE_0000140","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C117119T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}},"children":[{"name":"OQ331007","node_attrs":{"div":4,"accession":"OQ331007","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ331007/2023-01-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-01-03"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00398/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR499971","node_attrs":{"div":6,"accession":"OR499971","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499971/2023-05-04"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-05-04"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00514/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T39397C","T178873C","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG057":["N267D"]},"labels":{"aa":"OPG057: N267D"}}},{"name":"OR499970","node_attrs":{"div":4,"accession":"OR499970","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499970/2023-05-04"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-05-04"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00513/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T605-"]}}},{"name":"NODE_0000141","node_attrs":{"div":5,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T39076-","T39077-","T39078-","A39079-","A39080-","A39081-","T39082-","T39083-","T39084-","A176368T","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A190409-","A190410-","T190411-","G190412-","G190413-","A190414-","T190415-","T190416-","C190417-","G190418-","C190419-","G190420-","T190421-","A190422-","T190423-","A190424-","G190425-","C190426-","T190427-","A190428-","T190429-","T190430-","T190431-","A190432-","C190433-","G190434-","T190435-","A190436-","T190437-","T190438-","A190439-","G190440-","T190441-","A190442-","T190443-","C190444-","G190445-","G190446-","C190447-","A190448-","T190449-","C190450-","T190451-","C190452-","T190453-","T190454-","T190455-","T190456-","G190457-","T190458-","A190459-","T190460-","C190461-","T190462-","T190463-","G190464-","T190465-","T190466-","A190467-","A190468-","T190469-","T190470-","G190471-","T190472-","C190473-","A190474-","C190475-","A190476-","A190477-","A190478-","C190479-","T190480-","A190481-","G190482-","T190483-","A190484-","C190485-","A190486-","T190487-","T190488-","A190489-","C190490-","T190491-","T190492-","C190493-","A190494-","A190495-","T190496-","C190497-","T190498-","G190499-","A190500-","A190501-","A190502-","A190503-","T190504-","A190505-"],"OPG205":["E238V"]},"labels":{"aa":"OPG205: E238V"}},"children":[{"name":"OQ331005","node_attrs":{"div":5,"accession":"OQ331005","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ331005/2023-01-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-01-03"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00396/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR499968","node_attrs":{"div":5,"accession":"OR499968","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499968/2023-05-04"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-05-04"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00511/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000142","node_attrs":{"div":1,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C182950T"],"OPG210":["S532L"]},"labels":{"aa":"OPG210: S532L","clade":"B.1.12"}},"children":[{"name":"OP415207","node_attrs":{"div":3,"accession":"OP415207","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415207/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.12"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_BhVKjm_9000233"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G1302A","C57550T","G78328A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C195908T"],"OPG001":["L92F"],"OPG001_dup":["L92F"]},"labels":{"aa":"OPG001: L92F; OPG001_dup: L92F"}}},{"name":"NODE_0000143","node_attrs":{"div":2,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G111084A"]}},"children":[{"name":"ON880548","node_attrs":{"div":2,"accession":"ON880548","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/ON880548/2022-06-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-03"},"lineage":{"value":"B.1.12"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-3448/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR759170","node_attrs":{"div":8,"accession":"OR759170","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759170/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1.12"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL082/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G10060A","G37022A","G121510A","C132410T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G154793A","C180055T","-196615A"],"OPG055":["S21F"],"OPG181":["D128N"]},"labels":{"aa":"OPG055: S21F; OPG181: D128N"}}},{"name":"NODE_0000144","node_attrs":{"div":4,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G98233A","G98455A","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG117":["D729N"],"OPG118":["G4K"]},"labels":{"aa":"OPG117: D729N; OPG118: G4K"}},"children":[{"name":"ON880413","node_attrs":{"div":5,"accession":"ON880413","author":{"author":"Coletti,T.M.,Ghilardi,F.,khan,M.J.,Claro,I.M.,Valenca,I.N.,Faria,N.R.,Sabino,E.C.","value":"Coletti,T.M.,Ghilardi,F.,khan,M.J.,Claro,I.M.,Valenca,I.N.,Faria,N.R.,Sabino,E.C."},"strain_display":{"value":"Brazil/ON880413/2022-06-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"Imperial College London, School of Public Health"},"date":{"value":"2022-06-14"},"lineage":{"value":"B.1.12"},"country":{"value":"Brazil"},"strain":{"value":"MPX/BR0002/2022"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C76334T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG097":["R181K"]},"labels":{"aa":"OPG097: R181K"}}},{"name":"NODE_0000145","node_attrs":{"div":5,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G98456A","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T"]}},"children":[{"name":"OR209309","node_attrs":{"div":8,"accession":"OR209309","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"strain_display":{"value":"USA/OR209309/2022-12-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-12-XX"},"lineage":{"value":"B.1.12"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_TN0019"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C93601T","C94418T","T133101-","T133102-","C136029T","-179172C","-179173A","-179174T","-179175T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["A624V"],"OPG114":["E84K"]},"labels":{"aa":"OPG113: A624V; OPG114: E84K"}}},{"name":"NODE_0000146","node_attrs":{"div":6,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G153910A"],"OPG180":["E407K"]},"labels":{"aa":"OPG180: E407K"}},"children":[{"name":"OQ918701","node_attrs":{"div":11,"accession":"OQ918701","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ918701/2023-02-10"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-02-10"},"lineage":{"value":"B.1.12"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00490/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C21910T","G28483A","G39552A","A57421-","C57422-","A57423-","A57424-","A57425-","A57426-","A57427-","G57428-","G57429-","A57430-","C57431-","A57432-","T57433-","G57434-","T57435-","A57436-","A57437-","A57438-","C57439-","T57440-","T57441-","G132490A","C150443T","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG037":["R175K"],"OPG057":["S215F"],"OPG075":["K20-","F21-","T22-","C23-","P24-","F25-","C26-"],"OPG176":["T212I"]},"labels":{"aa":"OPG037: R175K; OPG057: S215F; OPG075: K20-, F21-, T22-, C23-, P24-, F25-, C26-; OPG176: T212I"}}},{"name":"OR759180","node_attrs":{"div":10,"accession":"OR759180","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759180/2022-09-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1.12"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL092/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C16209T","C24208T","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","G182088A","G182189A","A196614-"],"OPG027":["E57K"],"OPG210":["E245K"]},"labels":{"aa":"OPG027: E57K; OPG210: E245K"}}}]},{"name":"NODE_0000147","node_attrs":{"div":6,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C24231T","-179172C","-179173A","-179174T","-179175T"]}},"children":[{"name":"OP382485","node_attrs":{"div":7,"accession":"OP382485","author":{"author":"Colson,P.","value":"Colson,P."},"strain_display":{"value":"France/OP382485/2022-07-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1.12"},"country":{"value":"France"},"strain":{"value":"hMPXV-IHU00008"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G184227A"],"OPG210":["D958N"]},"labels":{"aa":"OPG210: D958N"}}},{"name":"OR264365","node_attrs":{"div":7,"accession":"OR264365","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264365/2022-07-18"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-18"},"lineage":{"value":"B.1.12"},"country":{"value":"Australia"},"strain":{"value":"12_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G23457A"],"OPG039":["S221F"]},"labels":{"aa":"OPG039: S221F"}}},{"name":"OR095032","node_attrs":{"div":7,"accession":"OR095032","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR095032/2022-08-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-08"},"lineage":{"value":"B.1.12"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_214/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G61102A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG080":["S306F"]},"labels":{"aa":"OPG080: S306F"}}}]}]}]}]}]},{"name":"NODE_0000148","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C9389T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A185557C"],"OPG210":["K1401T"]},"labels":{"aa":"OPG210: K1401T"}},"children":[{"name":"OQ261696","node_attrs":{"div":7,"accession":"OQ261696","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OQ261696/2022-10-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-10-13"},"lineage":{"value":"B.1"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-28205C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C13399T","G17339A","C49265T","C89906T","G94798A","C190859T","T196852-","G196853-","T196854-"],"OPG110":["S92F"],"OPG115":["E47K"]},"labels":{"aa":"OPG110: S92F; OPG115: E47K"}}},{"name":"NODE_0000149","node_attrs":{"div":4,"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C30154T","G161797A"],"OPG188":["E68K"]},"labels":{"aa":"OPG188: E68K","clade":"B.1.16"}},"children":[{"name":"OP459211","node_attrs":{"div":5,"accession":"OP459211","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OP459211/2022-08-29"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"date":{"value":"2022-08-29"},"lineage":{"value":"B.1.16"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-23596-O"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G170076A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP693653","node_attrs":{"div":5,"accession":"OP693653","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"strain_display":{"value":"Colombia/OP693653/2022-08-29"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-08-29"},"lineage":{"value":"B.1.16"},"country":{"value":"Colombia"},"strain":{"value":"DC_INS_MPX_0719_L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G121275A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG139":["P32S"]},"labels":{"aa":"OPG139: P32S"}}},{"name":"OP693647","node_attrs":{"div":4,"accession":"OP693647","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"strain_display":{"value":"Colombia/OP693647/2022-08-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-08-08"},"lineage":{"value":"B.1.16"},"country":{"value":"Colombia"},"strain":{"value":"DC_INS_MPX_0082_L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A1701-","C1702-","T1703-","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-","T196852-","G196853-","T196854-"]}}},{"name":"NODE_0000150","node_attrs":{"div":6,"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G23673A","G37974A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG039":["S149L"],"OPG056":["S354L"]},"labels":{"aa":"OPG039: S149L; OPG056: S354L"}},"children":[{"name":"OQ696097","node_attrs":{"div":6,"accession":"OQ696097","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OQ696097/2022-11-10"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-11-10"},"lineage":{"value":"B.1.16"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-30512O"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OQ696096","node_attrs":{"div":7,"accession":"OQ696096","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OQ696096/2022-11-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-11-08"},"lineage":{"value":"B.1.16"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-30280C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A164477G","A173314-","T173315-","A173316-","T173317-"],"OPG189":["E382G"]},"labels":{"aa":"OPG189: E382G"}}}]},{"name":"NODE_0000151","node_attrs":{"div":6,"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G148403A","G161421A"],"OPG187":["R267K"]},"labels":{"aa":"OPG187: R267K"}},"children":[{"name":"OP819953","node_attrs":{"div":8,"accession":"OP819953","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"strain_display":{"value":"Colombia/OP819953/2022-10-15"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-10-15"},"lineage":{"value":"B.1.16"},"country":{"value":"Colombia"},"strain":{"value":"VAC_INS_MPX_0960_L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G89896A","G164843A"],"OPG110":["E89K"],"OPG189":["G504E"]},"labels":{"aa":"OPG110: E89K; OPG189: G504E"}}},{"name":"NODE_0000152","node_attrs":{"div":8,"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G69840A","C178546T"]}},"children":[{"name":"OQ261702","node_attrs":{"div":8,"accession":"OQ261702","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OQ261702/2022-10-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-10-13"},"lineage":{"value":"B.1.16"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-28292C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000153","node_attrs":{"div":9,"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C117200T"]}},"children":[{"name":"OP819955","node_attrs":{"div":13,"accession":"OP819955","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"strain_display":{"value":"Colombia/OP819955/2022-10-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-10-13"},"lineage":{"value":"B.1.16"},"country":{"value":"Colombia"},"strain":{"value":"VAC_INS_MPX_0962_C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C53865T","C57810T","C124379T","C188775T"],"OPG071":["D192N"],"OPG145":["H145Y"]},"labels":{"aa":"OPG071: D192N; OPG145: H145Y"}}},{"name":"OP819949","node_attrs":{"div":12,"accession":"OP819949","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"strain_display":{"value":"Colombia/OP819949/2022-10-11"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-10-11"},"lineage":{"value":"B.1.16"},"country":{"value":"Colombia"},"strain":{"value":"VAC_INS_MPX_0955_C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C18133T","C89599T","G165412A"],"OPG190":["M97I"]},"labels":{"aa":"OPG190: M97I"}}}]}]}]}]}]},{"name":"NODE_0000154","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C112408T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG131":["L157F"]},"labels":{"aa":"OPG131: L157F"}},"children":[{"name":"OQ672571","node_attrs":{"div":3,"accession":"OQ672571","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"strain_display":{"value":"Belgium/OQ672571/2023-01-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2023-01-19"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"19012023_anal"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G69989A","C117978T","T145510-","T145511-","A145512-","C145513-","T145514-","T145515-","A145516-","A145517-","T145518-","A145519-","G145520-","A145521-","T145522-","T145523-","A145524-","T145525-","G145526-","T145527-","T146786-","A146787-","T146788-","T146789-","G146790-","T146791-","T146792-","A146793-","T146794-","C146795-","G146796-","T146797-","A146798-","A146799-","T146800-","T146801-","G146802-","G146803-","A146804-","A146805-","A146806-","A146807-","T146808-","T146809-","G146810-","G146811-","T146812-","A146813-","T146814-","T146815-","C146816-","A146817-","A146818-","G146819-","T146820-","G146821-","A146822-","G146823-","C146824-","T146825-","G146826-","G146827-","A146828-","T146829-","T146830-","A146831-","T146832-","G146833-","T146834-","G146835-","A146836-","G146837-","T146838-","A146839-","T146840-","T146841-","G146842-","G146843-","A146844-","T146845-","T146846-","G146847-","T146848-","A146849-","T146850-","A146851-","T146852-","T146853-","T146854-","T146855-","A146856-","T146857-","T146858-","T146859-","T146860-","A146861-","T146862-","A146863-","T146864-","T146865-","T146866-","T146867-","A146868-","T146869-","A146870-","T146871-","T146872-","T146873-","T146874-","A146875-","T146876-","A146877-","T146878-","T146879-","T146880-","T146881-","A146882-","T146883-","T146884-","T146885-","T146886-","A146887-","T146888-","A146889-","T146890-","T146891-","T146892-","T146893-","A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","G146913-","T146914-","A146915-","G146916-","T146917-","A146918-","A146919-","G146920-","A146921-","A146922-","T146923-","A146924-","G146925-","A146926-","A146927-","T146928-","G146929-","C146930-","T146931-","A146932-","A146933-","T146934-","G146935-","T146936-","C146937-","A146938-","A146939-","G146940-","T146941-","T146942-","T146943-","A146944-","T146945-","T146946-","C146947-","G146948-","A146949-","A146950-","T146951-","A146952-","G146953-","A146954-","T146955-","G146956-","T146957-","C146958-","T146959-","T146960-","A146961-","T146962-","T146963-","A146964-","A146965-","A146966-","A146967-","A146968-","A146969-","C146970-","A146971-","T146972-","A146973-","T146974-","A146975-","T146976-","A146977-","A146978-","T146979-","A146980-","A146981-","A146982-","T146983-","A146984-","A146985-","C146986-","A146987-","A146988-","T146989-","G146990-","G146991-","C146992-","T146993-","G146994-","A146995-","A146996-","T146997-","G146998-","G146999-","C147000-","A147001-","T147002-","A147003-","A147004-","A147005-","A147006-","T147007-","T147008-","A147009-","T147010-","C147011-","G147012-","A147013-","G147014-","G147015-","A147016-","T147017-","A147018-","T147019-","C147020-","T147021-","C147022-","A147023-","A147024-","A147025-","A147026-","A147027-","T169726-","A169727-"],"OPG089":["A42T"],"OPG136":["R537K"],"OPG197":["T20-"]},"labels":{"aa":"OPG089: A42T; OPG136: R537K; OPG197: T20-"}}},{"name":"NODE_0000155","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G6878A","C40894T","C67724T","C145201-","C145202-","A145203-","T145204-","T145205-","T145206-","A145207-","T180382-","A180383-","T180384-","T180385-","A180386-","C180387-","A180388-","A180389-","A180390-","T180391-","A180392-","G180393-","T180394-","A180395-","T180396-","A180397-","G180398-","C180399-","A180400-","T180401-","A180402-","A180403-","A180404-","C180405-","T180406-","A180407-","A180408-","A180409-","G180410-","T180411-","C180412-","G180413-","A180414-","T180415-","A180416-","C180417-","A180418-","T180419-","A180420-","C180421-","A180422-","T180423-","T180424-","A180425-","A180426-","A180427-","A180428-","C180429-","T180430-","T180431-","A180432-","A180433-","A180434-","T180435-","A180436-","A180437-","T180438-","A180439-","A180440-","T180441-","G180442-","T180443-","A180444-","A180445-","T180446-","T180447-","T180448-","A180449-","C180450-","A180451-","A180452-","T180453-","T180454-","A180455-","A180456-","T180457-","A180458-","G180459-","T180460-","A180461-","T180462-","A180463-","A180464-","A180465-","C180466-","T180467-","A180468-","A180469-","A180470-","A180471-","A180472-","A180473-","A180474-","T180475-","T180476-","A180477-","A180478-","A180479-","A180480-","A180481-","A180482-","T180483-","T180484-","A180485-","A180486-","A180487-","A180488-","A180489-","C180490-","A180491-","A180492-","T180493-","A180494-","T180495-","C180496-","A180497-","T180498-","T180499-","A180500-","T180501-","T180502-","A180503-","T180504-","A180505-","A180506-","G180507-","T180508-","A180509-","A180510-","T180511-","A180512-","T180513-","C180514-","A180515-","A180516-","A180535-","A180536-","T180537-","A180538-","G180539-","C180540-","G180541-","T180542-","A180543-","T180544-","C180545-","T180546-","T180547-","A180548-","T180549-","A180550-","T180551-","T180552-","C180553-","G180554-","T180555-","G180556-","A180557-","C180558-","T180559-","T180560-","C180561-","A180562-","T180563-","C180564-","C180565-","A180566-","T180567-","C180568-","G180569-","C180570-","T180571-","A180572-","G180573-","T180574-","C180575-","C180576-","A180577-","C180578-","T180579-","T180580-","T180581-","A180582-","C180583-","A180584-","T180585-","T180586-","C180587-","C180588-","C180589-","G180590-","T180591-","T180592-","A180593-","T180594-","T180595-","C180596-","C180597-","G180598-","C180599-","C180600-","C180601-","A180602-","T180603-","T180604-","T180605-","C180606-","G180607-","G180608-","A180609-","A180610-","G180611-","A180612-","T180613-","A180614-","A180615-","A180616-","T180617-","C180618-","G180619-","T180620-","T180621-","C180622-","A180623-","A180624-","T180625-","A180626-","G180627-","T180628-","G180629-","T180630-","A180631-","G180632-","A180633-","G180634-","G180635-","T180636-","A180637-","T180638-","T180639-","A180640-","G180641-","T180642-","T180643-","T180644-","C180645-","T180646-","T180647-","T180648-","G180649-","T180650-","T180651-","T180652-","C180653-","C180654-","C180655-","G180656-","A180657-","T180658-","G180659-","A180660-","C180661-","C180662-","A180663-","A180664-","A180665-","A180666-","A180667-","G180668-","A180669-","C180670-","T180671-","A180672-","T180673-","A180674-","C180675-","A180676-","G180677-","T180678-","A180679-","A180680-","C180681-","T180682-","T180683-","C180684-","T180685-","C180686-","A180687-","G180688-","T180689-","T180690-","C180691-","A180692-","A180693-","T180694-","A180695-","A180696-","C180697-","T180698-","A180699-","C180700-","A180701-","C180702-","T180703-","A180704-","T180705-","C180706-","G180707-","G180708-","T180709-","A180710-","C180711-","C180712-","A180713-","A180714-","A180715-","G180716-","A180717-","C180718-","T180719-","G180720-","G180721-","A180722-","C180723-","T180724-","A180725-","T180726-","C180727-","A180728-","A180729-","C180730-","G180731-","T180732-","A180733-","C180734-","T180735-","A180736-","T180737-","C180738-"],"OPG060":["G97R"],"OPG085":["E270K"],"OPG167":["K68-","W69-"]},"labels":{"aa":"OPG060: G97R; OPG085: E270K; OPG167: K68-, W69-"}},"children":[{"name":"OQ672575","node_attrs":{"div":6,"accession":"OQ672575","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"strain_display":{"value":"Belgium/OQ672575/2023-02-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2023-02-02"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"02022023_gluteal"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A125538G","G152986A"],"OPG180":["E99K"]},"labels":{"aa":"OPG180: E99K"}}},{"name":"OQ672573","node_attrs":{"div":5,"accession":"OQ672573","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"strain_display":{"value":"Belgium/OQ672573/2023-01-26"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2023-01-26"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"26012023_neck"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","T2653-","T2654-","T47709-","G47710-","T47742-","T47743-","A47744-","G47745-","G47746-","A47747-","C47748-","T47749-","A47750-","C47751-","T47752-","A47753-","C47754-","T47755-","C47756-","T47757-","A47758-","G47759-","A47760-","A47761-","G47762-","A47763-","T47764-","A47765-","T47766-","A47767-","G47768-","C47769-","A47770-","C47771-","C47772-","A47773-","T47774-","C47775-","T47776-","A47777-","T47778-","T47779-","C47780-","C47781-","A47782-","A47783-","A47784-","T47785-","A47786-","A47787-","T47788-","C47789-","A47790-","G47791-","A47792-","A47793-","A47794-","A47795-","C47796-","T47797-","T47798-","A47799-","T47800-","A47801-","A47802-","A47803-","C47804-","T47805-","A47806-","T47807-","T47808-","C47809-","T47810-","C47811-","G47812-","G47813-","A47814-","C47815-","A47816-","T47817-","T47818-","T47819-","C47820-","A47821-","G47822-","T47823-","C47824-","A47825-","T47826-","T47827-","G47828-","G47829-","C47830-","A47831-","A47960-","T47961-","G47962-","T47963-","A47964-","T47965-","G47966-","C47967-","C47968-","T47969-","G47970-","T47971-","T47972-","C47973-","G47974-","T47975-","A47976-","T47977-","G47978-","C47979-","C47980-","A48037-","G48038-","T48039-","C48069-","A48070-","T48071-","C48072-","A48113-","T48114-","A48115-","G48116-","T48117-","A48118-","C48176-","A48177-","T48178-","A48179-","G48180-","A48181-","T48182-","A48183-","A48184-","C48185-","T48186-","C48187-","T48188-","C48189-","T48190-","T48191-","C48192-","T48193-","A48194-","T48195-","A48196-","A48197-","A48198-","A48199-","A48200-","A48201-","T48202-","G48203-","G48204-","A48205-","T48206-","T48207-","T48208-","T48209-","A48210-","T48211-","T48212-","C48213-","G48214-","T48215-","A48216-","G48217-","A48218-","A48219-","A48220-","G48221-","T48222-","A48223-","T48224-","C48225-","T48226-","T48227-","A48228-","T48229-","A48230-","T48231-","A48232-","C48233-","A48234-","C48235-","A48236-","G48237-","T48238-","A48239-","G48240-","A48241-","A48289-","T48290-","A48330-","G48331-","C48332-","A48333-","A48334-","T48335-","T48336-","T48337-","T48338-","C48339-","T48366-","G48387-","T48388-","T48389-","T48390-","T48391-","C48392-","A48393-","T48394-","A48395-","C48396-","A48397-","C48435-","G48436-","A48437-","C48438-","A48439-","C48440-","G48441-","C48442-","A48443-","T48444-","T48445-","T48446-","G48447-","A48448-","T48449-","G48450-","C48451-","A48452-","A48571-","A48572-","T48573-","A48574-","C48575-","A48576-","T48577-","G48578-","G48579-","A48580-","C48581-","G48582-","A48583-","A48584-","T48585-","T48586-","A48587-","G48588-","G48589-","A48590-","G48591-","A48592-","A48593-","C48594-","T48595-","T48596-","A48597-","T48598-","A48599-","G48600-","G48601-","C48602-","G48603-","T48604-","A48605-","A48606-","A48607-","T48608-","T48609-","A48610-","T48611-","G48612-","A48613-","C48614-","T48615-","T48616-","A48617-","G48618-","T48619-","C48648-","C48649-","C48650-","A48651-","T48652-","C48653-","A48654-","A48655-","A48656-","G48657-","A48658-","T48659-","A48660-","T48661-","G48662-","G48663-","A48664-","A48665-","A48666-","T48667-","C48668-","A48669-","T48670-","T48671-","T48672-","T48673-","T48674-","A48759-","A48760-","A48761-","G48762-","A48763-","T48764-","A48765-","C48766-","A48767-","G48768-","G48769-","C48770-","A48771-","T48772-","A48773-","G48774-","G48780-","C48781-","G48782-","G48783-","A48784-","T48785-","A48786-","A48787-","T48788-","G48789-","A48790-","T48791-","A48792-","G48793-","A48794-","C48823A","C48837-","A48838-","T48839-","A48840-","G48841-","C48842-","A48843-","A48844-","T48845-","C48846-","T48847-","A48848-","A48849-","C48850-","A48851-","G48852-","A48853-","A48854-","A48855-","C48856-","G48857-","T48858-","T48859-","T48860-","A48861-","G48862-","G48863-","G48864-","A48865-","T48866-","T48867-","A48868-","T48869-","A48870-","T48871-","C48872-","T48873-","T48874-","T48875-","C48876-","C48877-","C48878-","G48879-","G48880-","A48881-","G48882-","A48883-","T48884-","A48885-","A48886-","G48887-","A48888-","C48889-","A48924-","A48925-","T48926-","G48927-","A48928-","T48929-","G48930-","C48931-","G48932-","G48933-","A48934-","A48987-","T48988-","A48989-","T48990-","A48991-","C48992-","T48993-","C48994-","T48995-","G48996-","A48997-","G48998-","A48999-","T49000-","A49001-","A49002-","A49003-","A49004-","C49005-","A49006-","G49007-","G49008-","G49009-","A49010-","C49011-","G49012-","C49013-","G49014-","T49015-","T49016-","A49017-","A49018-","T49019-","A49020-","A49021-","A49022-","A49023-","A49024-","C49025-","A49026-","T49027-","G49028-","C49029-","T49030-","T49031-","A49032-","A49033-","G49034-","T49035-","T49036-","A49037-","G49038-","T49039-","T49040-","T49041-","A49042-","T49043-","A49044-","T49045-","C49046-","T49047-","T49048-","T49049-","G49050-","A49051-","G49052-","C49053-","C49054-","T49157-","A49158-","T49159-","T49160-","A49161-","G49162-","T49163-","T49164-","T49165-","T49166-","T49167-","A49168-","C49169-","A49170-","A49171-","A49172-","G49173-","C49174-","T49175-","A49176-","A49177-","T49178-","T49179-","T49180-","T49181-","A49182-","T49183-","T49184-","A49185-","A49186-","C49187-","G49188-","G49189-","T49190-","A49191-","A49192-","T49193-","A49194-","C49195-","A49196-","T49197-","T49198-","T49199-","A49200-","T49201-","T49202-","A49203-","G49204-","T49205-","G49206-","A49207-","T49208-","A49209-","G49210-","A49211-","A49212-","C49213-","G49214-","T49215-","T49216-","T49217-","A49218-","A49219-","C49220-","G49221-","A49222-","T49223-","G49224-","A49225-","C49226-","T49227-","T49228-","A49229-","T49230-","T49231-","C49232-","A49233-","G49234-","A49235-","G49236-","T49237-","T49238-","G49239-","T49240-","T49241-","G49242-","T49243-","T49244-","C49245-","A49246-","A49247-","A49248-","T49249-","A49250-","G49251-","A49252-","T49253-","C49254-","C49255-","C49256-","G49257-","A49258-","A49259-","T49260-","A49261-","T49262-","T49263-","T49264-","C49265-","G49266-","A49267-","T49268-","A49269-","A49270-","T49271-","G49272-","A49273-","A49274-","C49275-","G49276-","A49277-","A49278-","T49279-","T49280-","A49281-","T49282-","G49283-","T49284-","C49285-","T49286-","T49287-","T49288-","A49289-","T49290-","T49291-","C49292-","T49293-","A49294-","T49295-","A49296-","C49297-","G49298-","A49299-","G49300-","T49301-","G49302-","C49303-","T49304-","G49305-","C49306-","G49307-","G49308-","A49309-","C49310-","A49311-","T49312-","T49313-","A49314-","A49315-","A49316-","C49317-","G49318-","A49319-","T49320-","T49321-","T49322-","G49323-","A49324-","T49325-","G49326-","A49327-","G49328-","T49329-","T49330-","A49331-","G49332-","A49333-","T49334-","A49335-","T49336-","T49337-","A49338-","A49339-","T49340-","A49341-","A49342-","C49343-","A49344-","G49345-","T49346-","T49347-","A49348-","T49349-","A49350-","T49351-","A49352-","T49353-","C49354-","T49355-","A49356-","A49357-","T49358-","A49407-","A49408-","G49409-","A49410-","A49411-","G49412-","T49413-","G49414-","T49415-","C49416-","A49417-","A49418-","A49419-","T49420-","T49473-","T49474-","G49475-","C49476-","A49477-","C49478-","G49479-","A49480-","G49481-","T49482-","C49483-","G49484-","G49485-","A49486-","T49487-","C49488-","C49489-","C49490-","A49491-","T49492-","G49493-","G49494-","T49495-","C49496-","A49497-","T49498-","A49499-","G49500-","A49501-","G49502-","A49503-","A49504-","C49505-","G49506-","G49507-","A49508-","A49509-","T49510-","A49511-","C49512-","T49513-","A49514-","A49515-","A49516-","G49517-","A49518-","A49519-","A49520-","C49521-","T49522-","G49523-","T49524-","C49525-","A49526-","T49527-","C49528-","T49529-","A49530-","T49531-","A49532-","A49533-","A49534-","A49535-","T49536-","C49537-","C49538-","A49539-","A49540-","G49541-","A49542-","G49543-","T49544-","A49545-","G49546-","A49547-","C49548-","G49549-","G49550-","C49551-","T49552-","G49553-","A49554-","A49555-","C49556-","T49557-","T49558-","G49559-","T49560-","T49561-","T49562-","A49563-","G49564-","C49565-","A49566-","A49567-","A49568-","A49569-","A49570-","C49571-","A49572-","T49573-","T49574-","T49575-","T49576-","A49577-","A49578-","A49579-","A49580-","T49581-","A49582-","T49583-","T49584-","A49585-","T49586-","T49587-","T49588-","A49589-","G49590-","A49591-","C49592-","G49593-","G49594-","A49595-","C49596-","A49597-","A49598-","T49599-","T49600-","G49601-","G49602-","C49603-","T49604-","C49605-","G49606-","T49607-","C49608-","T49609-","A49610-","G49611-","G49612-","T49613-","C49614-","T49615-","T49616-","G49617-","T49618-","G49619-","T49620-","T49621-","A49622-","G49623-","A49624-","T49625-","G49626-","A49627-","T49628-","T49629-","A49630-","T49631-","A49632-","A49633-","A49634-","G49635-","G49636-","A49637-","G49638-","A49639-","C49640-","T49641-","T49642-","A49643-","T49644-","T49645-","A49646-","G49647-","T49648-","T49649-","A49650-","A49651-","A49652-","A49653-","T49654-","G49655-","A49656-","T49657-","A49658-","A49659-","A49660-","C49661-","C49662-","A49663-","T49664-","C49665-","T49666-","C49667-","A49668-","A49669-","A49670-","T49671-","C49672-","T49673-","G49674-","T49675-","G49676-","G49677-","A49678-","G49679-","G49680-","A49681-","T49682-","G49683-","T49684-","A49685-","T49686-","C49687-","C49688-","G49689-","C49690-","A49691-","T49692-","T49693-","C49694-","G49695-","T49696-","T49697-","A49698-","G49699-","A49700-","T49701-","T49702-","T49703-","T49704-","C49705-","T49706-","A49707-","C49708-","A49709-","A62259-","G62260-","T62261-","T62262-","A62263-","C62305-","A62306-","A62307-","A62308-","G62309-","A62328-","G62329-","T62330-","T62331-","G62332-","T62333-","A62334-","T62335-","A62336-","C62337-","T62338-","G62339-","A62340-","G62341-","A62342-","A62343-","T62344-","T62345-","G62346-","A62347-","C62348-","G62349-","T62373-","T62374-","T62375-","C62376-","T62377-","A62412-","C62413-","T62414-","A62415-","G62416-","A62417-","C62418-","T62419-","T62420-","G62421-","A62422-","A62433-","G62434-","T62435-","A62436-","T62437-","A62438-","G62439-","A62535-","C62536-","G62552-","A62553-","G62554-","G62571-","C62572-","T62573-","T62574-","C62575-","T62576-","A62577-","G62578-","A62601-","C62624-","T62625-","A62626-","T62627-","C62628-","A62646-","C62647-","T62648-","C62649-","G62650-","C62651-","G62652-","T62653-","T62654-","T62655-","A62656-","G62657-","A62658-","G62659-","G62660-","A62661-","G62662-","T62663-","G62664-","A62665-","A62666-","C62667-","G62668-","T62669-","C62670-","T62671-","T62672-","C62673-","G62758-","T62759-","G62760-","G62761-","A62762-","A62763-","T62764-","T62765-","G62766-","A62767-","A62768-","G62769-","A62770-","T62771-","T62772-","C62773-","T62774-","A62775-","A62776-","T62777-","G62778-","G62779-","A62780-","T62781-","G62782-","A62783-","T62784-","G62785-","T62786-","T62787-","C62788-","T62789-","A62790-","C62791-","C62792-","T62793-","A62794-","T62795-","T62796-","T62797-","C62798-","A62799-","T62800-","C62801-","C62802-","G62803-","A62804-","T62805-","C62820-","A62821-","A62822-","T62823-","T62856-","A62857-","G62858-","T62859-","C62860-","T62861-","C62862-","T62863-","C62864-","T62865-","T62866-","T62867-","C62868-","G62869-","G62870-","A62871-","A62892-","T62893-","A62894-","C62895-","G62896-","A62897-","G62898-","T62899-","C62900-","A62901-","T62902-","T62903-","A62904-","T62905-","A62906-","T62907-","A62908-","C62909-","T62910-","C62911-","C62912-","T62931-","T62949-","G62950-","G62951-","G62952-","A62953-","C62967-","G62968-","A62969-","T62970-","A62982-","T62983-","C62984-","C62985-","G62986-","G62987-","A62988-","A62989-","C62990-","A62991-","T62992-","T62993-","G62994-","G63024-","G63025-","T63026-","A63027-","A63028-","G63029-","A63030-","A63031-","C63032-","A63042-","T63075-","T63076-","G63077-","A63078-","G63079-","A63080-","C63081-","T63082-","T63083-","G63084-","A63085-","T63086-","A63102-","T63103-","T63104-","C63143-","G63144-","T63145-","C63146-","G63147-","A63148-","C63149-","G63150-","C63151-","C63152-","A63153-","T63168-","G63169-","G63170-","A63171-","G63172-","T63173-","A63174-","C63240-","T63241-","C63242-","G63243-","T63244-","A63245-","C63246-","G63247-","C63248-","C63258-","A63259-","T63260-","G63261-","A63262-","T63263-","C63264-","A63265-","A63266-","G63267-","A63268-","G63269-","T63270-","G63271-","A63272-","T63273-","T63274-","T63275-","G63276-","A63277-","G63278-","A63279-","A63280-","C63281-","A63282-","T63283-","C63284-","C63285-","T63286-","C63287-","C63288-","A63311-","C63312-","A63313-","G63314-","T63315-","A63330-","T63331-","A63332-","A63333-","A63348-","A63349-","T63369-","A63370-","A63371-","A63372-","G63373-","A63374-","T63375-","T63385-","C63386-","T63387-","A63388-","A63389-","C63390-","G63391-","G63392-","A63393-","G63394-","A63395-","C63396-","A63397-","A63398-","T63399-","T63400-","T63401-","T63402-","T63403-","T63404-","G63405-","G63406-","T63407-","A63408-","G63409-","G63410-","T63411-","T63412-","T63413-","T63414-","A63415-","G63416-","A63417-","G63418-","A63419-","C63420-","T63421-","T63422-","T63423-","G63424-","A63425-","A63426-","G63427-","C63428-","T63429-","A63430-","C63431-","T63432-","T63433-","G63434-","T63435-","T63436-","T63437-","A63438-","A63439-","C63440-","A63441-","A63442-","A63443-","G63444-","T63445-","T63446-","A63447-","T63448-","T63449-","C63450-","A63451-","T63452-","C63453-","G63454-","T63455-","C63456-","T133098-","T133099-","T133100-","T133101-","T133102-","C180739-","A180740-"],"OPG002":["D34-","N35-"],"OPG068":["S44-","N45-","F46-","P47-","Q48-","H49-","L56-","V63-","F64-","I65-","H66-","M67-","V68-","R69-","H80-","A81-","F82-","D83-","A84-","P85-","Y125-","M126-","D127-","E128-","L129-","G130-","E131-","L132-","I133-","G134-","V135-","N136-","Y137-","D138-","L139-","V140-","N242-","D243-","A244-","D245-","I263-","Y264-","S265-","E266-","I267-","K268-","Q269-","G270-","R271-","V272-","N273-","K274-","N275-","M276-","L277-","K278-","L279-","V280-","Y281-","I282-","F283-","E284-","P285-","I320-","S321-","F322-","Y323-","K324-","A325-","N326-","F327-","I328-","N329-","G330-","N331-","T332-","F333-","I334-","S335-","D336-","R337-","T338-","F339-","N340-","D341-","D342-","L343-","F344-","R345-","V346-","V347-","V348-","Q349-","I350-","D351-","P352-","E353-","Y354-","F355-","D356-","N357-","E358-","R359-","I360-","M361-","S362-","L363-","F364-","Y365-","T366-","S367-","A368-","A369-","D370-","I371-","K372-","R373-","F374-","D375-","E376-","L377-","D378-","I379-","N380-","N381-","S382-","Y383-","I384-","S385-","N386-","I387-","K403-","K404-","C405-","Q406-","I407-"],"OPG081":["T9-"],"OPG082":["S27-","L28-","Y41-","L47-","F48-","T49-","K50-","E56-","D57-","V58-","L59-","K60-","S61-","L62-","L63-","I64-","M65-","N154-","V155-","P156-","D157-","S158-","S162-","P168-","F169-","D170-","L211-","E212-","I213-","N214-","M215-","L216-","S217-","D218-","E219-","I220-","G221-","R222-","T223-","S224-","S225-","I226-","R227-","I228-","F229-","S231M","T232F","K261-","T262-","F263-","T264-","P265-","L266-","N267-","A268-","S269-","I276-","V277-","R293-","S294-","T300N","H301-","Y339-","T340-","K345-","S346-","S347-"]},"labels":{"aa":"OPG002: D34-, N35-; OPG068: S44-, N45-, F46-, P47-, Q48-, H49-, L56-, V63-, F64-, I65-, H66-, M67-, V68-, R69-, H80-, A81-, F82-, D83-, A84-, P85-, Y125-, M126-, D127-, E128-, L129-, G130-, E131-, L132-, I133-, G134-, V135-, N136-, Y137-, D138-, L139-, V140-, N242-, D243-, A244-, D245-, I263-, Y264-, S265-, E266-, I267-, K268-, Q269-, G270-, R271-, V272-, N273-, K274-, N275-, M276-, L277-, K278-, L279-, V280-, Y281-, I282-, F283-, E284-, P285-, I320-, S321-, F322-, Y323-, K324-, A325-, N326-, F327-, I328-, N329-, G330-, N331-, T332-, F333-, I334-, S335-, D336-, R337-, T338-, F339-, N340-, D341-, D342-, L343-, F344-, R345-, V346-, V347-, V348-, Q349-, I350-, D351-, P352-, E353-, Y354-, F355-, D356-, N357-, E358-, R359-, I360-, M361-, S362-, L363-, F364-, Y365-, T366-, S367-, A368-, A369-, D370-, I371-, K372-, R373-, F374-, D375-, E376-, L377-, D378-, I379-, N380-, N381-, S382-, Y383-, I384-, S385-, N386-, I387-, K403-, K404-, C405-, Q406-, I407-; OPG081: T9-; OPG082: S27-, L28-, Y41-, L47-, F48-, T49-, K50-, E56-, D57-, V58-, L59-, K60-, S61-, L62-, L63-, I64-, M65-, N154-, V155-, P156-, D157-, S158-, S162-, P168-, F169-, D170-, L211-, E212-, I213-, N214-, M215-, L216-, S217-, D218-, E219-, I220-, G221-, R222-, T223-, S224-, S225-, I226-, R227-, I228-, F229-, S231M, T232F, K261-, T262-, F263-, T264-, P265-, L266-, N267-, A268-, S269-, I276-, V277-, R293-, S294-, T300N, H301-, Y339-, T340-, K345-, S346-, S347-"}}}]},{"name":"NODE_0000156","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G47746-","A62110-","T62111-","A62112-","A62113-","A62114-","A62116-","T62118-","T62121-","A62122-","T62123-","A62124-","T62125-","A62126-","T62127-","T62128-","T62129-","A62131-","A62132-","A62133-","A62134-","T62135-","T62138-","T62139-","A62140-","T62144-","T62145-","A62148-","T62149-","T62150-","A62151-","A62167-","T62168-","T62169-","T62171-","A62173-","A62174-","T62175-","A62176-","T62177-","A62178-","T62179-","A62181-","T62182-","T62183-","A62184-","A62187-","T62188-","T62189-","T62190-","A62191-","A62192-","T62194-","T62197-","T62198-","A62200-","T62202-","A62203-","T62204-","A62206-","T62207-","T62213-","A62217-","A62219-","A62220-","A62221-","T62222-","T62223-","A62224-","A62227-","T62228-","A62230-","A62231-","A62232-","A62233-","A62236-","T62237-","T62238-","A62239-","A62240-","T62241-","A62242-","A62244-","T62246-","T62247-","A62248-","T62249-","A62252-","A62254-","T62255-","A62259-","T62261-","T62262-","A62263-","A62265-","A62266-","T62270-","T62271-","A62272-","T62273-","A62274-","A62277-","T62278-","A62281-","A62284-","T62285-","T62286-","T62287-","A62288-","T62289-","A62290-","T62291-","T62293-","A62294-","A62295-","A62296-","A62297-","A62298-","T62299-","T62300-","A62301-","A62303-","T62304-","A62306-","A62307-","A62308-","A62310-","A62311-","T62312-","A62313-","T62314-","T62316-","A62318-","A62320-","A62321-","T62324-","T62327-","A62328-","T62330-","T62331-","T62333-","A62334-","T62335-","A62336-","T62338-","A62340-","A62342-","A62343-","T62344-","T62345-","A62347-","A62350-","A62351-","A62352-","A62354-","A62355-","T62356-","T62358-","T62359-","T62360-","T62362-","T62363-","A62364-","A62366-","T62367-","A62368-","T62369-","T62370-","T62371-","T62372-","T62373-","T62374-","T62375-","T62377-","T62378-","A62379-","T62380-","T62381-","A62382-","T62384-","A62385-","A62386-","A62390-","T62392-","T62393-","A62394-","A62395-","T62396-","A62397-","T62399-","A62400-","A62403-","A62404-","T62406-","A62409-","A62410-","A62411-","A62412-","T62414-","A62415-","A62417-","T62419-","T62420-","A62422-","T62423-","T62424-","A62425-","T62426-","T62427-","T62429-","A62430-","T62431-","A62432-","A62433-","T62435-","A62436-","T62437-","A62438-","A62440-","T62441-","A62442-","T62446-","T62447-","A62450-","A62451-","A62452-","T62453-","A62454-","A62455-","T62456-","T62458-","T62459-","T62461-","T62463-","T62464-","T62465-","A62467-","T62468-","A62469-","A62470-","A62471-","A62472-","T62474-","T62475-","A62478-","A62480-","A62481-","A62482-","A62483-","T62484-","T62486-","A62487-","A62489-","A62490-","T62491-","T62492-","T62493-","T62494-","T62495-","T62496-","A62497-","A62498-","A62499-","A62500-","A62501-","T62503-","T62504-","A62505-","T62506-","T62508-","T62509-","T62510-","T62511-","T62514-","A62515-","T62516-","T62517-","A62518-","T62520-","A62521-","A62522-","T62523-","A62524-","T62525-","T62528-","T62531-","T62532-","A62533-","A62535-","T62539-","T62540-","A62541-","T62542-","T62543-","A62544-","T62545-","T62546-","A62547-","A62548-","T62549-","A62550-","T62551-","A62553-","T62555-","A62557-","T62558-","A62560-","A62561-","A62562-","T62563-","A62566-","A62568-","T62573-","T62574-","T62576-","A62577-","A62579-","T62580-","A62581-","T62582-","T62586-","T62587-","T62588-","T62589-","A62590-","T62591-","T62592-","T62593-","A62596-","A62598-","T62599-","T62600-","A62601-","A62603-","T62604-","T62607-","A62608-","A62609-","A62610-","T62611-","A62614-","A62615-","T62616-","A62617-","T62619-","A62621-","A62622-","A62623-","T62625-","A62626-","T62627-","T62629-","T62630-","A62703-","T62704-","A62705-","A62706-","A62707-","A62709-","A62710-","T62711-","T62712-","T62713-","A62715-","A62717-","A62718-","A62719-","T62720-","A62723-","T62724-","T62726-","T62727-","A62728-","A62729-","T62730-","T62732-","A62733-","T62734-","T62735-","A62736-","T62738-","A62739-","A62742-","A62743-","A62744-","T62745-","T62746-","T62747-","T62748-","T62749-","T62750-","A62752-","T62756-","A62757-","T62759-","A62762-","A62763-","T62764-","T62765-","A62767-","A62768-","A62770-","T62771-","T62772-","T62774-","A62775-","A62776-","T62777-","A62780-","T62781-","A62783-","T62784-","T62786-","T62787-","T62789-","A62790-","T62793-","A62794-","T62795-","T62796-","T62797-","A62799-","T62800-","A62804-","T62805-","A62806-","A62807-","A62809-","T62810-","T62812-","T62813-","A62814-","A62815-","T62816-","T62817-","T62818-","A62821-","A62822-","T62823-","A62824-","A62827-","A62828-","T62832-","T62833-","T62834-","T62835-","A62836-","A62837-","T62838-","A62839-","T62840-","T62841-","T62842-","A62845-","T62846-","A62848-","T62849-","A62850-","T62851-","A62852-","T62856-","A62857-","T62859-","T62861-","C62862-","T62863-","T62865-","T62866-","T62867-","A62871-","T62873-","T62874-","A62875-","T62876-","A62877-","T62878-","A62879-","T62882-","T62883-","A62884-","T62885-","T62886-","A62889-","A62891-","A62892-","T62893-","A62894-","A62897-","T62899-","A62901-","T62902-","T62903-","A62904-","T62905-","A62906-","T62907-","A62908-","T62910-","A62913-","A62914-","A62915-","A62916-","A62917-","A62918-","A62920-","A62921-","A62922-","A62923-","T62924-","A62925-","A62926-","T62928-","A62929-","T62931-","A62932-","T62933-","A62934-","A62935-","A62936-","A62937-","T62938-","T62940-","T62942-","A62943-","T62944-","A62947-","A62948-","T62949-","A62953-","A62954-","A62955-","A62956-","A62957-","A62960-","A62961-","A62962-","T62963-","T62964-","A62965-","T62966-","A62969-","T62970-","A62971-","T62972-","A62973-","T62976-","A62977-","T62978-","A62979-","A62981-","A62982-","T62983-","A62988-","A62989-","A62991-","T62992-","T62993-","A62995-","A62996-","T62999-","A63000-","T63001-","T63002-","A63003-","A63004-","T63005-","A63006-","T63008-","T63009-","A63010-","A63011-","T63012-","T63013-","T63015-","T63016-","T63017-","T63018-","T63019-","A63021-","T63023-","T63026-","A63027-","A63028-","A63030-","A63031-","A63035-","T63036-","A63037-","T63040-","T63041-","A63042-","T63043-","T63044-","A63046-","A63048-","T63049-","T63050-","T63052-","A63053-","T63054-","T63057-","T63058-","T63059-","T63060-","A63061-","A63062-","A63063-","T63064-","A63065-","T63066-","T63067-","T63069-","A63070-","T63071-","A63072-","A63073-","T63075-","T63076-","A63078-","A63080-","T63082-","T63083-","A63085-","T63086-","A63087-","A63089-","T63090-","A63091-","T63092-","T63093-","A63094-","A63095-","T63096-","A63098-","A63101-","A63102-","T63103-","T63104-","A63106-","A63107-","A63108-","A63109-","T63110-","T63111-","A63112-","T63113-","T63114-","T63115-","T63116-","T63117-","A63118-","T63119-","A63121-","A63124-","T63127-","T63129-","T63131-","T63132-","T63133-","A63135-","A63138-","T63139-","A63141-","T63142-","T63145-","A63148-","A63153-","T63155-","T63156-","A63157-","A63158-","A63161-","A63162-","A63166-","A63167-","T63168-","A63171-","T63173-","A63174-","A63175-","A63176-","A63177-","T63178-","A63179-","A63180-","A63181-","T63182-","A63183-","T63184-","A63186-","T63187-","T63188-","A63189-","A63190-","T63191-","A63192-","T63193-","A63194-","T63195-","T63198-","T63200-","A63201-","A63203-","T63204-","A63205-","T63206-","T63207-","A63208-","T63210-","A63211-","T63212-","T63213-","T63214-","T63215-","T63216-","A63217-","T63218-","T63219-","A63220-","A63221-","T63222-","T63225-","T63226-","T63227-","A63229-","T63230-","T63231-","A63232-","T63233-","A63235-","T63236-","T63238-","T63239-","T63241-","T63244-","A63245-","A63250-","A63251-","T63252-","A63254-","T63255-","T63256-","A63259-","T63260-","A63262-","T63263-","A63265-","A63266-","A63268-","T63270-","A63272-","T63273-","T63274-","T63275-","A63277-","A63279-","A63280-","A63282-","T63283-","T63286-","A63291-","T63293-","A63294-","T63295-","T63296-","A63297-","A63298-","T63299-","T63303-","T63304-","T63305-","A63306-","T63308-","A63309-","A63310-","A63311-","A63313-","T63315-","A63318-","T63319-","T63322-","T63323-","A63326-","A63327-","T63328-","A63329-","A63330-","T63331-","A63332-","A63333-","A63334-","A63335-","T63337-","T63338-","T63340-","A63343-","A63344-","T63346-","T63347-","A63348-","A63349-","A63350-","A63353-","T63354-","A63355-","T63356-","T63357-","A63358-","T63359-","A63362-","T63363-","T63364-","T63367-","T63368-","T63369-","A63370-","A63371-","A63372-","A63374-","T63375-","A63376-","T63377-","A63379-","T63382-","A63384-","T63385-","T63387-","A63388-","A63389-","A63393-","A63395-","A63397-","A63398-","T63399-","T63400-","T63401-","T63402-","T63403-","T63404-","T63407-","A63408-","T63411-","T63412-","T63413-","T63414-","A63415-","A63417-","A63419-","T63421-","T63422-","T63423-","A63425-","A63426-","T63429-","A63430-","T63432-","T63433-","T63435-","T63436-","T63437-","A63438-","A63439-","A63441-","A63442-","A63443-","T63445-","T63446-","A63447-","T63448-","T63449-","A63451-","T63452-","T63455-","T63458-","T63460-","A63461-","T63463-","A63464-","T63465-","T63466-","T63468-","A63469-","T63470-","T63471-","T63472-","A63473-","A63474-","T63475-","T63476-","T63477-","T63478-","T63480-","A63481-","T63483-","T63484-","A63485-","A63486-","T63487-","T63488-","T63489-","A63490-","T63491-","A63493-","A63495-","T63496-","A63497-","T63498-","A63500-","A63502-","T63503-","T63504-","C89166T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"]}},"children":[{"name":"OQ672570","node_attrs":{"div":2,"accession":"OQ672570","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"strain_display":{"value":"Belgium/OQ672570/2022-11-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-11-02"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"02112022_anal"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G49680-","G49710-","G62109-","G62115-","G62117-","C62119-","C62120-","G62130-","C62136-","G62137-","C62141-","G62142-","G62143-","C62146-","G62147-","C62166-","G62170-","G62172-","C62180-","G62185-","G62186-","C62193-","C62195-","C62196-","G62199-","C62201-","C62205-","G62208-","G62209-","C62210-","G62211-","G62212-","G62214-","C62215-","C62216-","G62218-","C62225-","C62226-","C62229-","G62234-","C62235-","C62243-","G62245-","G62250-","C62251-","G62253-","C62256-","G62257-","C62258-","G62260-","G62264-","C62267-","G62268-","G62269-","G62275-","C62276-","C62279-","C62280-","C62282-","C62283-","C62292-","G62302-","C62305-","G62309-","G62315-","G62317-","C62319-","C62322-","G62323-","C62325-","C62326-","G62329-","G62332-","C62337-","G62339-","G62341-","G62346-","C62348-","G62349-","C62353-","G62357-","C62361-","C62365-","C62376-","G62383-","C62387-","C62388-","G62389-","C62391-","G62398-","G62401-","G62402-","C62405-","G62407-","G62408-","C62413-","G62416-","C62418-","G62421-","C62428-","G62434-","G62439-","C62443-","C62444-","C62445-","C62448-","C62449-","G62457-","C62460-","C62462-","G62466-","G62473-","C62476-","C62477-","G62479-","G62485-","G62488-","G62502-","C62507-","G62512-","C62513-","C62519-","C62526-","G62527-","G62529-","G62530-","G62534-","C62536-","G62537-","C62538-","G62552-","G62554-","G62556-","G62559-","C62564-","C62565-","C62567-","C62569-","C62570-","G62571-","C62572-","C62575-","G62578-","C62583-","G62584-","C62585-","C62594-","C62595-","C62597-","G62602-","G62605-","G62606-","C62612-","C62613-","G62618-","G62620-","C62624-","C62628-","C62708-","C62714-","C62716-","G62721-","G62722-","G62725-","G62731-","G62737-","G62740-","G62741-","G62751-","C62753-","G62754-","C62755-","G62758-","G62760-","G62761-","G62766-","G62769-","C62773-","G62778-","G62779-","G62782-","G62785-","C62788-","C62791-","C62792-","C62798-","C62801-","C62802-","G62803-","C62808-","G62811-","C62819-","C62820-","C62825-","C62826-","C62829-","G62830-","G62831-","C62843-","G62844-","G62847-","C62853-","G62854-","G62855-","G62858-","C62860-","C62864-","C62868-","G62869-","G62870-","C62872-","G62880-","C62881-","C62887-","C62888-","C62890-","C62895-","G62896-","G62898-","C62900-","C62909-","C62911-","C62912-","C62919-","C62927-","G62930-","C62939-","G62941-","C62945-","G62946-","G62950-","G62951-","G62952-","C62958-","G62959-","C62967-","G62968-","G62974-","G62975-","G62980-","C62984-","C62985-","G62986-","G62987-","C62990-","G62994-","C62997-","G62998-","C63007-","C63014-","C63020-","G63022-","G63024-","G63025-","G63029-","C63032-","C63033-","G63034-","G63038-","G63039-","G63045-","C63047-","G63051-","G63055-","G63056-","C63068-","C63074-","G63077-","G63079-","C63081-","G63084-","G63088-","G63097-","C63099-","G63100-","G63105-","C63120-","C63122-","C63123-","C63125-","G63126-","G63128-","G63130-","C63134-","G63136-","G63137-","C63140-","C63143-","G63144-","C63146-","G63147-","C63149-","G63150-","C63151-","C63152-","G63154-","C63159-","C63160-","C63163-","C63164-","G63165-","G63169-","G63170-","G63172-","C63185-","G63196-","C63197-","C63199-","G63202-","G63209-","C63223-","C63224-","G63228-","C63234-","C63237-","C63240-","C63242-","G63243-","C63246-","G63247-","C63248-","G63249-","G63253-","C63257-","C63258-","G63261-","C63264-","G63267-","G63269-","G63271-","G63276-","G63278-","C63281-","C63284-","C63285-","C63287-","C63288-","G63289-","G63290-","G63292-","G63300-","G63301-","G63302-","G63307-","C63312-","G63314-","C63316-","C63317-","C63320-","G63321-","G63324-","C63325-","G63336-","G63339-","C63341-","C63342-","G63345-","G63351-","G63352-","G63360-","C63361-","C63365-","G63366-","G63373-","C63378-","C63380-","C63381-","C63383-","C63386-","C63390-","G63391-","G63392-","G63394-","C63396-","G63405-","G63406-","G63409-","G63410-","G63416-","G63418-","C63420-","G63424-","G63427-","C63428-","C63431-","G63434-","C63440-","G63444-","C63450-","C63453-","G63454-","C63456-","G63457-","C63459-","C63462-","C63467-","G63479-","G63482-","C63492-","C63494-","C63499-","C63501-","-180517A","-180518A","-180519T","-180520G","-180521A","-180522C","-180523G","-180524A","-180525T","-180526A","-180527T","-180528A","-180529C","-180530G","-180531G","-180532A","-180533T","-180534T"],"OPG068":["D494-"],"OPG081":["N46-","R47-","T48-","V49-","T50-","I51-","F52-","K53-","Y54-","I55-","G56-","L57-","F58-","I59-"]},"labels":{"aa":"OPG068: D494-; OPG081: N46-, R47-, T48-, V49-, T50-, I51-, F52-, K53-, Y54-, I55-, G56-, L57-, F58-, I59-"}}},{"name":"NODE_0000157","node_attrs":{"div":6,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C2621-","A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","C8201T","-62110A","-62111T","-62112A","-62113A","-62114A","-62116A","-62118T","-62121T","-62122A","-62123T","-62124A","-62125T","-62126A","-62127T","-62128T","-62129T","-62131A","-62132A","-62133A","-62134A","-62135T","-62138T","-62139T","-62140A","-62144T","-62145T","-62148A","-62149T","-62150T","-62151A","-62167A","-62168T","-62169T","-62171T","-62173A","-62174A","-62175T","-62176A","-62177T","-62178A","-62179T","-62181A","-62182T","-62183T","-62184A","-62187A","-62188T","-62189T","-62190T","-62191A","-62192A","-62194T","-62197T","-62198T","-62200A","-62202T","-62203A","-62204T","-62206A","-62207T","-62213T","-62217A","-62219A","-62220A","-62221A","-62222T","-62223T","-62224A","-62227A","-62228T","-62230A","-62231A","-62232A","-62233A","-62236A","-62237T","-62238T","-62239A","-62240A","-62241T","-62242A","-62244A","-62246T","-62247T","-62248A","-62249T","-62252A","-62254A","-62255T","-62259A","-62261T","-62262T","-62263A","-62265A","-62266A","-62270T","-62271T","-62272A","-62273T","-62274A","-62277A","-62278T","-62281A","-62284A","-62285T","-62286T","-62287T","-62288A","-62289T","-62290A","-62291T","-62293T","-62294A","-62295A","-62296A","-62297A","-62298A","-62299T","-62300T","-62301A","-62303A","-62304T","-62306A","-62307A","-62308A","-62310A","-62311A","-62312T","-62313A","-62314T","-62316T","-62318A","-62320A","-62321A","-62324T","-62327T","-62328A","-62330T","-62331T","-62333T","-62334A","-62335T","-62336A","-62338T","-62340A","-62342A","-62343A","-62344T","-62345T","-62347A","-62350A","-62351A","-62352A","-62354A","-62355A","-62356T","-62358T","-62359T","-62360T","-62362T","-62363T","-62364A","-62366A","-62367T","-62368A","-62369T","-62370T","-62371T","-62372T","-62373T","-62374T","-62375T","-62377T","-62378T","-62379A","-62380T","-62381T","-62382A","-62384T","-62385A","-62386A","-62390A","-62392T","-62393T","-62394A","-62395A","-62396T","-62397A","-62399T","-62400A","-62403A","-62404A","-62406T","-62409A","-62410A","-62411A","-62412A","-62414T","-62415A","-62417A","-62419T","-62420T","-62422A","-62423T","-62424T","-62425A","-62426T","-62427T","-62429T","-62430A","-62431T","-62432A","-62433A","-62435T","-62436A","-62437T","-62438A","-62440A","-62441T","-62442A","-62446T","-62447T","-62450A","-62451A","-62452A","-62453T","-62454A","-62455A","-62456T","-62458T","-62459T","-62461T","-62463T","-62464T","-62465T","-62467A","-62468T","-62469A","-62470A","-62471A","-62472A","-62474T","-62475T","-62478A","-62480A","-62481A","-62482A","-62483A","-62484T","-62486T","-62487A","-62489A","-62490A","-62491T","-62492T","-62493T","-62494T","-62495T","-62496T","-62497A","-62498A","-62499A","-62500A","-62501A","-62503T","-62504T","-62505A","-62506T","-62508T","-62509T","-62510T","-62511T","-62514T","-62515A","-62516T","-62517T","-62518A","-62520T","-62521A","-62522A","-62523T","-62524A","-62525T","-62528T","-62531T","-62532T","-62533A","-62535A","-62539T","-62540T","-62541A","-62542T","-62543T","-62544A","-62545T","-62546T","-62547A","-62548A","-62549T","-62550A","-62551T","-62553A","-62555T","-62557A","-62558T","-62560A","-62561A","-62562A","-62563T","-62566A","-62568A","-62573T","-62574T","-62576T","-62577A","-62579A","-62580T","-62581A","-62582T","-62586T","-62587T","-62588T","-62589T","-62590A","-62591T","-62592T","-62593T","-62596A","-62598A","-62599T","-62600T","-62601A","-62603A","-62604T","-62607T","-62608A","-62609A","-62610A","-62611T","-62614A","-62615A","-62616T","-62617A","-62619T","-62621A","-62622A","-62623A","-62625T","-62626A","-62627T","-62629T","-62630T","-62703A","-62704T","-62705A","-62706A","-62707A","-62709A","-62710A","-62711T","-62712T","-62713T","-62715A","-62717A","-62718A","-62719A","-62720T","-62723A","-62724T","-62726T","-62727T","-62728A","-62729A","-62730T","-62732T","-62733A","-62734T","-62735T","-62736A","-62738T","-62739A","-62742A","-62743A","-62744A","-62745T","-62746T","-62747T","-62748T","-62749T","-62750T","-62752A","-62756T","-62757A","-62759T","-62762A","-62763A","-62764T","-62765T","-62767A","-62768A","-62770A","-62771T","-62772T","-62774T","-62775A","-62776A","-62777T","-62780A","-62781T","-62783A","-62784T","-62786T","-62787T","-62789T","-62790A","-62793T","-62794A","-62795T","-62796T","-62797T","-62799A","-62800T","-62804A","-62805T","-62806A","-62807A","-62809A","-62810T","-62812T","-62813T","-62814A","-62815A","-62816T","-62817T","-62818T","-62821A","-62822A","-62823T","-62824A","-62827A","-62828A","-62832T","-62833T","-62834T","-62835T","-62836A","-62837A","-62838T","-62839A","-62840T","-62841T","-62842T","-62845A","-62846T","-62848A","-62849T","-62850A","-62851T","-62852A","-62856T","-62857A","-62859T","-62863T","-62865T","-62866T","-62867T","-62871A","-62873T","-62874T","-62875A","-62876T","-62877A","-62878T","-62879A","-62882T","-62883T","-62884A","-62885T","-62886T","-62889A","-62891A","-62892A","-62893T","-62894A","-62897A","-62899T","-62901A","-62902T","-62903T","-62904A","-62905T","-62906A","-62907T","-62908A","-62910T","-62913A","-62914A","-62915A","-62916A","-62917A","-62918A","-62920A","-62921A","-62922A","-62923A","-62924T","-62925A","-62926A","-62928T","-62929A","-62931T","-62932A","-62933T","-62934A","-62935A","-62936A","-62937A","-62938T","-62940T","-62942T","-62943A","-62944T","-62947A","-62948A","-62949T","-62953A","-62954A","-62955A","-62956A","-62957A","-62960A","-62961A","-62962A","-62963T","-62964T","-62965A","-62966T","-62969A","-62970T","-62971A","-62972T","-62973A","-62976T","-62977A","-62978T","-62979A","-62981A","-62982A","-62983T","-62988A","-62989A","-62991A","-62992T","-62993T","-62995A","-62996A","-62999T","-63000A","-63001T","-63002T","-63003A","-63004A","-63005T","-63006A","-63008T","-63009T","-63010A","-63011A","-63012T","-63013T","-63015T","-63016T","-63017T","-63018T","-63019T","-63021A","-63023T","-63026T","-63027A","-63028A","-63030A","-63031A","-63035A","-63036T","-63037A","-63040T","-63041T","-63042A","-63043T","-63044T","-63046A","-63048A","-63049T","-63050T","-63052T","-63053A","-63054T","-63057T","-63058T","-63059T","-63060T","-63061A","-63062A","-63063A","-63064T","-63065A","-63066T","-63067T","-63069T","-63070A","-63071T","-63072A","-63073A","-63075T","-63076T","-63078A","-63080A","-63082T","-63083T","-63085A","-63086T","-63087A","-63089A","-63090T","-63091A","-63092T","-63093T","-63094A","-63095A","-63096T","-63098A","-63101A","-63102A","-63103T","-63104T","-63106A","-63107A","-63108A","-63109A","-63110T","-63111T","-63112A","-63113T","-63114T","-63115T","-63116T","-63117T","-63118A","-63119T","-63121A","-63124A","-63127T","-63129T","-63131T","-63132T","-63133T","-63135A","-63138A","-63139T","-63141A","-63142T","-63145T","-63148A","-63153A","-63155T","-63156T","-63157A","-63158A","-63161A","-63162A","-63166A","-63167A","-63168T","-63171A","-63173T","-63174A","-63175A","-63176A","-63177A","-63178T","-63179A","-63180A","-63181A","-63182T","-63183A","-63184T","-63186A","-63187T","-63188T","-63189A","-63190A","-63191T","-63192A","-63193T","-63194A","-63195T","-63198T","-63200T","-63201A","-63203A","-63204T","-63205A","-63206T","-63207T","-63208A","-63210T","-63211A","-63212T","-63213T","-63214T","-63215T","-63216T","-63217A","-63218T","-63219T","-63220A","-63221A","-63222T","-63225T","-63226T","-63227T","-63229A","-63230T","-63231T","-63232A","-63233T","-63235A","-63236T","-63238T","-63239T","-63241T","-63244T","-63245A","-63250A","-63251A","-63252T","-63254A","-63255T","-63256T","-63259A","-63260T","-63262A","-63263T","-63265A","-63266A","-63268A","-63270T","-63272A","-63273T","-63274T","-63275T","-63277A","-63279A","-63280A","-63282A","-63283T","-63286T","-63291A","-63293T","-63294A","-63295T","-63296T","-63297A","-63298A","-63299T","-63303T","-63304T","-63305T","-63306A","-63308T","-63309A","-63310A","-63311A","-63313A","-63315T","-63318A","-63319T","-63322T","-63323T","-63326A","-63327A","-63328T","-63329A","-63330A","-63331T","-63332A","-63333A","-63334A","-63335A","-63337T","-63338T","-63340T","-63343A","-63344A","-63346T","-63347T","-63348A","-63349A","-63350A","-63353A","-63354T","-63355A","-63356T","-63357T","-63358A","-63359T","-63362A","-63363T","-63364T","-63367T","-63368T","-63369T","-63370A","-63371A","-63372A","-63374A","-63375T","-63376A","-63377T","-63379A","-63382T","-63384A","-63385T","-63387T","-63388A","-63389A","-63393A","-63395A","-63397A","-63398A","-63399T","-63400T","-63401T","-63402T","-63403T","-63404T","-63407T","-63408A","-63411T","-63412T","-63413T","-63414T","-63415A","-63417A","-63419A","-63421T","-63422T","-63423T","-63425A","-63426A","-63429T","-63430A","-63432T","-63433T","-63435T","-63436T","-63437T","-63438A","-63439A","-63441A","-63442A","-63443A","-63445T","-63446T","-63447A","-63448T","-63449T","-63451A","-63452T","-63455T","-63458T","-63460T","-63461A","-63463T","-63464A","-63465T","-63466T","-63468T","-63469A","-63470T","-63471T","-63472T","-63473A","-63474A","-63475T","-63476T","-63477T","-63478T","-63480T","-63481A","-63483T","-63484T","-63485A","-63486A","-63487T","-63488T","-63489T","-63490A","-63491T","-63493A","-63495A","-63496T","-63497A","-63498T","-63500A","-63502A","-63503T","-63504T","C151552T","C167451T","G187391A","A194549-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-"],"OPG002":["R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-","C47-"],"OPG002_dup":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-"],"OPG178":["S15F"]},"labels":{"aa":"OPG002: R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-, C47-; OPG002_dup: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-; OPG178: S15F"}},"children":[{"name":"OQ672572","node_attrs":{"div":6,"accession":"OQ672572","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"strain_display":{"value":"Belgium/OQ672572/2023-01-26"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2023-01-26"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"26012023_anal"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-47746G","-62861T","-62862C"]}}},{"name":"OQ672574","node_attrs":{"div":6,"accession":"OQ672574","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"strain_display":{"value":"Belgium/OQ672574/2023-02-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2023-02-02"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"02022023_anal"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-2623A","-2624C","-2625A","-2626T","-2627A","-2628G","-2629A","-2630T","-2631T","-2632A","-2633C","-2634G","-2635G","-2636C","-2637T","-2638T","-2639C","-2640T","-2641G","-2642T","-2643A","-2644T","-2645T","-2646C","-2647G","-2648T","-2649T","-2650G","-2651T","-2652C","-194549A","-194550A","-194551G","-194552T","-194553G","-194554T","-194555A","-194556A","-194557A","-194558G","-194559A","-194560C","-194561A","-194562A","-194563C","-194564G","-194565A","-194566A","-194567T","-194568A","-194569C","-194570A","-194571G","-194572A","-194573A","-194574G","-194575C","-194576C","-194577G","-194578T","-194579A","-194580A","-194581T","-194582C","-194583T","-194584A","-194585T"],"OPG002":["-38R","-39S","-40R","-41N","-42L","-43C","-45L","-46S","-47C"],"OPG002_dup":["-31K","-32C","-33K","-34D","-35N","-36E","-37Y","-38R","-39S","-40R","-41N","-42L","-43C"]},"labels":{"aa":"OPG002: -38R, -39S, -40R, -41N, -42L, -43C, -45L, -46S, -47C; OPG002_dup: -31K, -32C, -33K, -34D, -35N, -36E, -37Y, -38R, -39S, -40R, -41N, -42L, -43C"}}},{"name":"NODE_0000158","node_attrs":{"div":7,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A2611-","C2612-","A2613-","C2614-","G2615-","A2616-","T2617-","A2618-","G2619-","A2620-","A2622-","T2653-","T2654-","T2655-","A2656-","C2657-","A2658-","C2659-","T2660-","T2661-","T39397C","T47695-","C47696-","A47697-","T47698-","T47699-","A47700-","C47701-","G47702-","A47703-","G47704-","A47705-","C47706-","A47707-","T47708-","T47709-","G47710-","A47711-","A47712-","A47713-","C47714-","T47715-","A47716-","G47717-","G47718-","A47719-","T47720-","A47721-","T47722-","A47723-","T47724-","A47725-","A47726-","A47727-","A47728-","T47729-","T47730-","T47731-","A47732-","A47733-","G47734-","G47735-","G47736-","A47737-","A47738-","T47739-","G47740-","A47741-","T47742-","T47743-","A47744-","G47745-","A47747-","C47748-","T47749-","A47750-","C47751-","T47752-","A47753-","C47754-","T47755-","C47756-","T47757-","A47758-","G47759-","A47760-","A47761-","G47762-","A47763-","T47764-","A47765-","T47766-","A47767-","G47768-","C47769-","A47770-","C47771-","C47772-","A47773-","T47774-","C47775-","T47776-","A47777-","T47778-","T47779-","C47780-","C47781-","A47782-","A47783-","A47784-","T47785-","A47786-","A47787-","T47788-","C47789-","A47790-","G47791-","A47792-","A47793-","A47794-","A47795-","C47796-","T47797-","T47798-","A47799-","T47800-","A47801-","A47802-","A47803-","C47804-","T47805-","A47806-","T47807-","T47808-","C47809-","T47810-","C47811-","G47812-","G47813-","A47814-","C47815-","A47816-","T47817-","T47818-","T47819-","C47820-","A47821-","G47822-","T47823-","C47824-","A47825-","T47826-","T47827-","G47828-","G47829-","C47830-","A47831-","A47832-","A47833-","G47834-","C47835-","A47836-","T47837-","C47838-","A47839-","C47840-","A47841-","G47842-","A47843-","A47844-","T47845-","C47846-","C47847-","G47848-","A47849-","G47850-","T47851-","A47852-","A47853-","G47854-","A47855-","T47856-","G47857-","A47858-","T47859-","A47860-","T47861-","A47862-","T47863-","G47864-","C47865-","T47866-","C47867-","G47868-","C47869-","T47870-","G47871-","C47872-","T47873-","T47874-","T47875-","A47876-","C47877-","A47878-","T47879-","G47880-","T47881-","T47882-","T47883-","C47884-","C47885-","C47886-","A47887-","A47888-","T47889-","T47890-","T47891-","G47892-","T47893-","T47894-","T47895-","G47896-","G47897-","A47898-","G47899-","A47900-","T47901-","G47902-","A47903-","C47904-","C47905-","A47906-","T47907-","A47908-","G47909-","A47910-","T47911-","T47912-","C47913-","A47914-","T47915-","T47916-","T47917-","G47918-","T47919-","T47920-","A47921-","T47922-","A47923-","G47924-","A47925-","A47926-","T47927-","G47928-","C47929-","A47930-","T47931-","C47932-","C47933-","A47934-","A47935-","C47936-","A47937-","T47938-","T47939-","G47940-","T47941-","T47942-","C47943-","A47944-","T47945-","G47946-","A47947-","T47948-","A47949-","T47950-","A47951-","G47952-","T47953-","T47954-","G47955-","A47956-","A47957-","T47958-","C47959-","A47960-","T47961-","G47962-","T47963-","A47964-","T47965-","G47966-","C47967-","C47968-","T47969-","G47970-","T47971-","T47972-","C47973-","G47974-","T47975-","A47976-","T47977-","G47978-","C47979-","C47980-","T47981-","G47982-","T47983-","G47984-","G47985-","C47986-","T47987-","A47988-","A47989-","G47990-","A47991-","T47992-","A47993-","C47994-","T47995-","G47996-","T47997-","G47998-","T47999-","A48000-","A48001-","A48002-","G48003-","A48004-","A48005-","A48006-","T48007-","G48008-","G48009-","T48010-","A48011-","A48012-","A48013-","T48014-","A48015-","A48016-","A48017-","T48018-","A48019-","C48020-","T48021-","T48022-","T48023-","G48024-","A48025-","G48026-","A48027-","A48028-","T48029-","C48030-","T48031-","T48032-","T48033-","A48034-","A48035-","G48036-","A48037-","G48038-","T48039-","G48040-","C48041-","A48042-","T48043-","T48044-","G48045-","A48046-","C48047-","T48048-","T48049-","T48050-","G48051-","T48052-","T48053-","A48054-","G48055-","T48056-","G48057-","A48058-","A48059-","T48060-","A48061-","G48062-","G48063-","C48064-","A48065-","T48066-","T48067-","C48068-","C48069-","A48070-","T48071-","C48072-","T48073-","T48074-","T48075-","C48076-","T48077-","C48078-","C48079-","A48080-","A48081-","T48082-","A48083-","C48084-","T48085-","A48086-","A48087-","T48088-","T48089-","C48090-","A48091-","A48092-","A48093-","T48094-","T48095-","G48096-","T48097-","T48098-","A48099-","A48100-","A48101-","T48102-","T48103-","A48104-","A48105-","T48106-","A48107-","A48108-","T48109-","G48110-","G48111-","A48112-","A48113-","T48114-","A48115-","G48116-","T48117-","A48118-","T48119-","A48120-","A48121-","A48122-","T48123-","A48124-","G48125-","T48126-","T48127-","A48128-","T48129-","T48130-","A48131-","G48132-","T48133-","G48134-","A48135-","T48136-","A48137-","G48138-","G48139-","A48140-","T48141-","A48142-","G48143-","T48144-","A48145-","A48146-","A48147-","C48148-","A48149-","T48150-","A48151-","A48152-","T48153-","T48154-","A48155-","T48156-","T48157-","A48158-","G48159-","A48160-","A48161-","T48162-","A48163-","G48164-","T48165-","A48166-","G48167-","T48168-","G48169-","T48170-","A48171-","G48172-","T48173-","A48174-","T48175-","C48176-","A48177-","T48178-","A48179-","G48180-","A48181-","T48182-","A48183-","A48184-","C48185-","T48186-","C48187-","T48188-","C48189-","T48190-","T48191-","C48192-","T48193-","A48194-","T48195-","A48196-","A48197-","A48198-","A48199-","A48200-","A48201-","T48202-","G48203-","G48204-","A48205-","T48206-","T48207-","T48208-","T48209-","A48210-","T48211-","T48212-","C48213-","G48214-","T48215-","A48216-","G48217-","A48218-","A48219-","A48220-","G48221-","T48222-","A48223-","T48224-","C48225-","T48226-","T48227-","A48228-","T48229-","A48230-","T48231-","A48232-","C48233-","A48234-","C48235-","A48236-","G48237-","T48238-","A48239-","G48240-","A48241-","A48242-","A48243-","A48244-","T48245-","A48246-","A48247-","T48248-","A48249-","T48250-","A48251-","G48252-","A48253-","T48254-","T48255-","T48256-","T48257-","T48258-","T48259-","A48260-","A48261-","A48262-","G48263-","G48264-","A48265-","T48266-","G48267-","A48268-","T48269-","A48270-","C48271-","A48272-","T48273-","T48274-","A48275-","A48276-","G48277-","T48278-","A48279-","A48280-","A48281-","G48282-","T48283-","A48284-","A48285-","A48286-","C48287-","A48288-","A48289-","T48290-","T48291-","T48292-","T48293-","A48294-","C48295-","C48296-","C48297-","T48298-","C48299-","A48300-","A48301-","T48302-","C48303-","A48304-","T48305-","G48306-","T48307-","A48308-","C48309-","T48310-","A48311-","G48312-","C48313-","T48314-","C48315-","T48316-","C48317-","A48318-","A48319-","G48320-","T48321-","A48322-","T48323-","C48324-","T48325-","A48326-","G48327-","T48328-","T48329-","A48330-","G48331-","C48332-","A48333-","A48334-","T48335-","T48336-","T48337-","T48338-","C48339-","C48340-","T48341-","C48342-","A48343-","A48344-","C48345-","A48346-","T48347-","G48348-","T48349-","T48350-","A48351-","T48352-","T48353-","A48354-","C48355-","T48356-","A48357-","A48358-","G48359-","G48360-","A48361-","T48362-","G48363-","T48364-","A48365-","T48366-","T48367-","A48368-","G48369-","C48370-","T48371-","A48372-","A48373-","T48374-","A48375-","C48376-","C48377-","A48378-","A48379-","T48380-","T48381-","T48382-","T48383-","T48384-","T48385-","T48386-","G48387-","T48388-","T48389-","T48390-","T48391-","C48392-","A48393-","T48394-","A48395-","C48396-","A48397-","T48398-","A48399-","T48400-","G48401-","G48402-","T48403-","A48404-","C48405-","G48406-","A48407-","T48408-","G48409-","C48410-","T48411-","G48412-","T48413-","A48414-","A48415-","A48416-","G48417-","T48418-","A48419-","T48420-","A48421-","C48422-","G48423-","A48424-","A48425-","G48426-","C48427-","G48428-","G48429-","T48430-","T48431-","T48432-","T48433-","A48434-","C48435-","G48436-","A48437-","C48438-","A48439-","C48440-","G48441-","C48442-","A48443-","T48444-","T48445-","T48446-","G48447-","A48448-","T48449-","G48450-","C48451-","A48452-","C48453-","C48454-","C48455-","A48456-","C48457-","G48458-","T48459-","T48460-","G48461-","T48462-","A48463-","C48464-","G48465-","T48466-","T48467-","A48468-","A48469-","A48470-","G48471-","C48472-","A48473-","T48474-","T48475-","G48476-","A48477-","C48478-","T48479-","A48480-","A48481-","G48482-","A48483-","A48484-","T48485-","T48486-","A48487-","T48488-","T48489-","T48490-","A48491-","T48492-","C48493-","G48494-","T48495-","T48496-","T48497-","A48498-","G48499-","T48500-","A48501-","A48502-","C48503-","A48504-","C48505-","A48506-","A48507-","T48508-","A48509-","C48510-","A48511-","G48512-","T48513-","C48514-","G48515-","T48516-","A48517-","C48518-","A48519-","A48520-","G48521-","G48522-","A48523-","A48524-","A48525-","C48526-","A48527-","G48528-","T48529-","G48530-","C48531-","A48532-","T48533-","A48534-","A48535-","A48536-","C48537-","T48538-","A48539-","A48540-","C48541-","A48542-","C48543-","A48544-","A48545-","G48546-","A48547-","T48548-","G48549-","A48550-","A48551-","A48552-","A48553-","A48554-","T48555-","T48556-","T48557-","T48558-","T48559-","A48560-","G48561-","A48562-","G48563-","G48564-","T48565-","T48566-","G48567-","C48568-","C48569-","G48570-","A48571-","A48572-","T48573-","A48574-","C48575-","A48576-","T48577-","G48578-","G48579-","A48580-","C48581-","G48582-","A48583-","A48584-","T48585-","T48586-","A48587-","G48588-","G48589-","A48590-","G48591-","A48592-","A48593-","C48594-","T48595-","T48596-","A48597-","T48598-","A48599-","G48600-","G48601-","C48602-","G48603-","T48604-","A48605-","A48606-","A48607-","T48608-","T48609-","A48610-","T48611-","G48612-","A48613-","C48614-","T48615-","T48616-","A48617-","G48618-","T48619-","T48620-","C48621-","T48622-","T48623-","A48624-","A48625-","T48626-","C48627-","C48628-","A48629-","T48630-","T48631-","A48632-","T48633-","T48634-","T48635-","C48636-","A48637-","C48638-","G48639-","G48640-","A48641-","G48642-","G48643-","G48644-","G48645-","A48646-","A48647-","C48648-","C48649-","C48650-","A48651-","T48652-","C48653-","A48654-","A48655-","A48656-","G48657-","A48658-","T48659-","A48660-","T48661-","G48662-","G48663-","A48664-","A48665-","A48666-","T48667-","C48668-","A48669-","T48670-","T48671-","T48672-","T48673-","T48674-","T48675-","T48676-","A48677-","A48678-","A48679-","A48680-","C48681-","T48682-","G48683-","T48684-","T48685-","T48686-","A48687-","A48688-","G48689-","A48690-","A48691-","A48692-","A48693-","C48694-","A48695-","G48696-","A48697-","C48698-","T48699-","T48700-","C48701-","A48702-","A48703-","A48704-","G48705-","T48706-","T48707-","G48708-","T48709-","T48710-","A48711-","A48712-","A48713-","A48714-","A48715-","A48716-","T48717-","T48718-","A48719-","A48720-","G48721-","T48722-","G48723-","T48724-","T48725-","A48726-","T48727-","A48728-","A48729-","G48730-","A48731-","T48732-","T48733-","A48734-","C48735-","T48736-","T48737-","A48738-","T48739-","T48740-","T48741-","G48742-","G48743-","G48744-","C48745-","A48746-","T48747-","A48748-","C48749-","C48750-","T48751-","A48752-","A48753-","G48754-","C48755-","A48756-","A48757-","G48758-","A48759-","A48760-","A48761-","G48762-","A48763-","T48764-","A48765-","C48766-","A48767-","G48768-","G48769-","C48770-","A48771-","T48772-","A48773-","G48774-","A48775-","G48776-","T48777-","T48778-","T48779-","G48780-","C48781-","G48782-","G48783-","A48784-","T48785-","A48786-","A48787-","T48788-","G48789-","A48790-","T48791-","A48792-","G48793-","A48794-","C48795-","A48796-","A48797-","G48798-","A48799-","T48800-","A48801-","T48802-","A48803-","T48804-","A48805-","T48806-","A48807-","C48808-","T48809-","C48810-","T48811-","A48812-","T48813-","T48814-","T48815-","C48816-","A48817-","A48818-","C48819-","A48820-","A48821-","A48822-","C48823-","T48824-","G48825-","G48826-","T48827-","A48828-","G48829-","A48830-","A48831-","T48832-","A48833-","G48834-","T48835-","C48836-","C48837-","A48838-","T48839-","A48840-","G48841-","C48842-","A48843-","A48844-","T48845-","C48846-","T48847-","A48848-","A48849-","C48850-","A48851-","G48852-","A48853-","A48854-","A48855-","C48856-","G48857-","T48858-","T48859-","T48860-","A48861-","G48862-","G48863-","G48864-","A48865-","T48866-","T48867-","A48868-","T48869-","A48870-","T48871-","C48872-","T48873-","T48874-","T48875-","C48876-","C48877-","C48878-","G48879-","G48880-","A48881-","G48882-","A48883-","T48884-","A48885-","A48886-","G48887-","A48888-","C48889-","T48890-","A48891-","G48892-","C48893-","T48894-","A48895-","T48896-","T48897-","G48898-","G48899-","G48900-","T48901-","G48902-","T48903-","G48904-","G48905-","T48906-","T48907-","A48908-","A48909-","A48910-","C48911-","G48912-","A48913-","A48914-","A48915-","G48916-","T48917-","A48918-","T48919-","A48920-","G48921-","C48922-","T48923-","A48924-","A48925-","T48926-","G48927-","A48928-","T48929-","G48930-","C48931-","G48932-","G48933-","A48934-","T48935-","A48936-","T48937-","C48938-","G48939-","T48940-","T48941-","A48942-","T48943-","T48944-","A48945-","A48946-","T48947-","A48948-","G48949-","A48950-","C48951-","C48952-","C48953-","G48954-","C48955-","C48956-","A48957-","T48958-","T48959-","A48960-","C48961-","C48962-","A48963-","T48964-","G48965-","T48966-","A48967-","T48968-","G48969-","A48970-","T48971-","A48972-","A48973-","A48974-","A48975-","T48976-","T48977-","C48978-","T48979-","T48980-","A48981-","G48982-","T48983-","T48984-","A48985-","T48986-","A48987-","T48988-","A48989-","T48990-","A48991-","C48992-","T48993-","C48994-","T48995-","G48996-","A48997-","G48998-","A48999-","T49000-","A49001-","A49002-","A49003-","A49004-","C49005-","A49006-","G49007-","G49008-","G49009-","A49010-","C49011-","G49012-","C49013-","G49014-","T49015-","T49016-","A49017-","A49018-","T49019-","A49020-","A49021-","A49022-","A49023-","A49024-","C49025-","A49026-","T49027-","G49028-","C49029-","T49030-","T49031-","A49032-","A49033-","G49034-","T49035-","T49036-","A49037-","G49038-","T49039-","T49040-","T49041-","A49042-","T49043-","A49044-","T49045-","C49046-","T49047-","T49048-","T49049-","G49050-","A49051-","G49052-","C49053-","C49054-","T49055-","G49056-","A49057-","A49058-","A49059-","A49060-","A49061-","G49062-","A49063-","T49064-","A49065-","T49066-","C49067-","A49068-","G49069-","A49070-","G49071-","A49072-","A49073-","C49074-","T49075-","T49076-","C49077-","T49078-","G49079-","C49080-","T49081-","A49082-","G49083-","A49084-","A49085-","A49086-","T49087-","C49088-","A49089-","T49090-","A49091-","T49092-","A49093-","T49094-","G49095-","A49096-","T49097-","A49098-","T49099-","T49100-","C49101-","C49102-","T49103-","G49104-","G49105-","A49106-","G49107-","A49108-","T49109-","A49110-","T49111-","C49112-","C49113-","T49114-","A49115-","T49116-","C49117-","T49118-","A49119-","T49120-","T49121-","A49122-","T49123-","T49124-","G49125-","A49126-","T49127-","G49128-","C49129-","A49130-","A49131-","A49132-","A49133-","A49134-","A49135-","C49136-","G49137-","A49138-","C49139-","G49140-","A49141-","T49142-","T49143-","G49144-","G49145-","A49146-","A49147-","A49148-","A49149-","A49150-","A49151-","T49152-","A49153-","T49154-","T49155-","T49156-","T49157-","A49158-","T49159-","T49160-","A49161-","G49162-","T49163-","T49164-","T49165-","T49166-","T49167-","A49168-","C49169-","A49170-","A49171-","A49172-","G49173-","C49174-","T49175-","A49176-","A49177-","T49178-","T49179-","T49180-","T49181-","A49182-","T49183-","T49184-","A49185-","A49186-","C49187-","G49188-","G49189-","T49190-","A49191-","A49192-","T49193-","A49194-","C49195-","A49196-","T49197-","T49198-","T49199-","A49200-","T49201-","T49202-","A49203-","G49204-","T49205-","G49206-","A49207-","T49208-","A49209-","G49210-","A49211-","A49212-","C49213-","G49214-","T49215-","T49216-","T49217-","A49218-","A49219-","C49220-","G49221-","A49222-","T49223-","G49224-","A49225-","C49226-","T49227-","T49228-","A49229-","T49230-","T49231-","C49232-","A49233-","G49234-","A49235-","G49236-","T49237-","T49238-","G49239-","T49240-","T49241-","G49242-","T49243-","T49244-","C49245-","A49246-","A49247-","A49248-","T49249-","A49250-","G49251-","A49252-","T49253-","C49254-","C49255-","C49256-","G49257-","A49258-","A49259-","T49260-","A49261-","T49262-","T49263-","T49264-","C49265-","G49266-","A49267-","T49268-","A49269-","A49270-","T49271-","G49272-","A49273-","A49274-","C49275-","G49276-","A49277-","A49278-","T49279-","T49280-","A49281-","T49282-","G49283-","T49284-","C49285-","T49286-","T49287-","T49288-","A49289-","T49290-","T49291-","C49292-","T49293-","A49294-","T49295-","A49296-","C49297-","G49298-","A49299-","G49300-","T49301-","G49302-","C49303-","T49304-","G49305-","C49306-","G49307-","G49308-","A49309-","C49310-","A49311-","T49312-","T49313-","A49314-","A49315-","A49316-","C49317-","G49318-","A49319-","T49320-","T49321-","T49322-","G49323-","A49324-","T49325-","G49326-","A49327-","G49328-","T49329-","T49330-","A49331-","G49332-","A49333-","T49334-","A49335-","T49336-","T49337-","A49338-","A49339-","T49340-","A49341-","A49342-","C49343-","A49344-","G49345-","T49346-","T49347-","A49348-","T49349-","A49350-","T49351-","A49352-","T49353-","C49354-","T49355-","A49356-","A49357-","T49358-","A49359-","T49360-","A49361-","A49362-","T49363-","T49364-","T49365-","A49366-","T49367-","G49368-","A49369-","G49370-","G49371-","T49372-","G49373-","A49374-","A49375-","C49376-","G49377-","A49378-","T49379-","A49380-","T49381-","C49382-","A49383-","C49384-","A49385-","T49386-","T49387-","A49388-","G49389-","A49390-","T49391-","A49392-","C49393-","A49394-","A49395-","T49396-","G49397-","G49398-","A49399-","T49400-","G49401-","A49402-","T49403-","A49404-","T49405-","G49406-","A49407-","A49408-","G49409-","A49410-","A49411-","G49412-","T49413-","G49414-","T49415-","C49416-","A49417-","A49418-","A49419-","T49420-","C49421-","T49422-","T49423-","T49424-","A49425-","A49426-","C49427-","G49428-","A49429-","G49430-","G49431-","A49432-","T49433-","A49434-","C49435-","G49436-","T49437-","T49438-","G49439-","T49440-","A49441-","T49442-","T49443-","A49444-","T49445-","G49446-","T49447-","T49448-","A49449-","A49450-","G49451-","G49452-","A49453-","A49454-","T49455-","A49456-","C49457-","A49458-","A49459-","T49460-","A49461-","C49462-","A49463-","T49464-","A49465-","C49466-","C49467-","T49468-","G49469-","T49470-","T49471-","T49472-","T49473-","T49474-","G49475-","C49476-","A49477-","C49478-","G49479-","A49480-","G49481-","T49482-","C49483-","G49484-","G49485-","A49486-","T49487-","C49488-","C49489-","C49490-","A49491-","T49492-","G49493-","G49494-","T49495-","C49496-","A49497-","T49498-","A49499-","G49500-","A49501-","G49502-","A49503-","A49504-","C49505-","G49506-","G49507-","A49508-","A49509-","T49510-","A49511-","C49512-","T49513-","A49514-","A49515-","A49516-","G49517-","A49518-","A49519-","A49520-","C49521-","T49522-","G49523-","T49524-","C49525-","A49526-","T49527-","C49528-","T49529-","A49530-","T49531-","A49532-","A49533-","A49534-","A49535-","T49536-","C49537-","C49538-","A49539-","A49540-","G49541-","A49542-","G49543-","T49544-","A49545-","G49546-","A49547-","C49548-","G49549-","G49550-","C49551-","T49552-","G49553-","A49554-","A49555-","C49556-","T49557-","T49558-","G49559-","T49560-","T49561-","T49562-","A49563-","G49564-","C49565-","A49566-","A49567-","A49568-","A49569-","A49570-","C49571-","A49572-","T49573-","T49574-","T49575-","T49576-","A49577-","A49578-","A49579-","A49580-","T49581-","A49582-","T49583-","T49584-","A49585-","T49586-","T49587-","T49588-","A49589-","G49590-","A49591-","C49592-","G49593-","G49594-","A49595-","C49596-","A49597-","A49598-","T49599-","T49600-","G49601-","G49602-","C49603-","T49604-","C49605-","G49606-","T49607-","C49608-","T49609-","A49610-","G49611-","G49612-","T49613-","C49614-","T49615-","T49616-","G49617-","T49618-","G49619-","T49620-","T49621-","A49622-","G49623-","A49624-","T49625-","G49626-","A49627-","T49628-","T49629-","A49630-","T49631-","A49632-","A49633-","A49634-","G49635-","G49636-","A49637-","G49638-","A49639-","C49640-","T49641-","T49642-","A49643-","T49644-","T49645-","A49646-","G49647-","T49648-","T49649-","A49650-","A49651-","A49652-","A49653-","T49654-","G49655-","A49656-","T49657-","A49658-","A49659-","A49660-","C49661-","C49662-","A49663-","T49664-","C49665-","T49666-","C49667-","A49668-","A49669-","A49670-","T49671-","C49672-","T49673-","G49674-","T49675-","G49676-","G49677-","A49678-","G49679-","G49680-","A49681-","T49682-","G49683-","T49684-","A49685-","T49686-","C49687-","C49688-","G49689-","C49690-","A49691-","T49692-","T49693-","C49694-","G49695-","T49696-","T49697-","A49698-","G49699-","A49700-","T49701-","T49702-","T49703-","T49704-","C49705-","T49706-","A49707-","C49708-","A49709-","G49710-","A49711-","G61794-","G61795-","C61796-","A61797-","T61798-","A61815-","G61816-","T61817-","A61818-","C61819-","A61820-","A61821-","G61822-","T61823-","G61824-","G61825-","C61826-","T61827-","G61828-","C61829-","T61830-","A61831-","T61832-","T61833-","T61834-","C61835-","G61836-","G61837-","C61838-","T61839-","G61840-","C61841-","C61842-","A61843-","G61844-","A61845-","G61846-","T61847-","G61848-","T61849-","C61850-","C61851-","A61852-","A61853-","T61854-","T61855-","C61856-","T61857-","A61858-","C61859-","C61860-","G61861-","T61862-","T61863-","G61864-","T61865-","T61866-","A61867-","C61868-","T61869-","C61870-","C61871-","A61872-","T61873-","T61874-","A61875-","T61876-","A61877-","T61878-","A61879-","T61880-","T61881-","C61882-","C61883-","T61884-","T61885-","G61886-","A61887-","A61888-","T61889-","A61890-","A61891-","C61892-","C61893-","T61894-","T61895-","C61896-","A61897-","T61898-","A61899-","G61900-","C61901-","T61902-","A61903-","T61904-","T61905-","T61906-","T61907-","A61908-","A61909-","T61910-","A61911-","G61912-","G61913-","A61914-","T61915-","C61916-","T61917-","A61918-","T61919-","A61920-","T61921-","G61922-","A61923-","T61924-","C61925-","A61926-","G61927-","T61928-","G61929-","T61930-","T61931-","T61932-","A61933-","A61934-","G61935-","C61936-","C61937-","A61938-","T61939-","A61940-","G61941-","C61942-","A61943-","C61944-","A61945-","A61946-","T61947-","T61948-","T61949-","T61950-","C61951-","T61952-","A61953-","A61954-","T61955-","A61956-","C61957-","G61958-","A61959-","G61960-","A61961-","C61962-","G61963-","T61964-","G61965-","A61966-","T61967-","T61968-","T61969-","T61970-","A61971-","T61972-","C61973-","A61974-","A61975-","A61976-","C61977-","A61978-","T61979-","G61980-","A61981-","C61982-","A61983-","T61984-","T61985-","T61986-","T61987-","C61988-","C61989-","T61990-","T61991-","G61992-","T61993-","A61994-","T61995-","C61996-","C61997-","A61998-","T61999-","T62000-","T62001-","C62002-","G62003-","T62004-","T62005-","T62006-","A62007-","A62008-","T62009-","G62010-","A62011-","C62012-","A62013-","A62014-","A62015-","C62016-","A62017-","T62018-","T62019-","T62020-","T62021-","T62022-","G62023-","T62024-","T62025-","G62026-","G62027-","T62028-","G62029-","T62030-","A62031-","A62032-","T62033-","A62034-","A62035-","A62036-","A62037-","A62038-","A62039-","A62040-","A62041-","T62042-","T62043-","A62044-","T62045-","T62046-","T62047-","A62048-","A62049-","T62050-","T62051-","T62052-","T62053-","T62054-","C62055-","A62056-","T62057-","T62058-","A62059-","A62060-","T62061-","A62062-","G62063-","G62064-","G62065-","A62066-","T62067-","T62068-","T62069-","G62070-","A62071-","C62072-","G62073-","T62074-","A62075-","T62076-","G62077-","T62078-","A62079-","G62080-","C62081-","G62082-","T62083-","A62084-","C62085-","A62086-","A62087-","A62088-","A62089-","T62090-","T62091-","A62092-","T62093-","C62094-","G62095-","T62096-","T62097-","C62098-","C62099-","T62100-","G62101-","G62102-","T62103-","A62104-","T62105-","A62106-","T62107-","A62108-","G62109-","A62110-","T62111-","A62112-","A62113-","A62114-","G62115-","A62116-","G62117-","T62118-","C62119-","C62120-","T62121-","A62122-","T62123-","A62124-","T62125-","A62126-","T62127-","T62128-","T62129-","G62130-","A62131-","A62132-","A62133-","A62134-","T62135-","C62136-","G62137-","T62138-","T62139-","A62140-","C62141-","G62142-","G62143-","T62144-","T62145-","C62146-","G62147-","A62148-","T62149-","T62150-","A62151-","A62152-","A62153-","C62154-","T62155-","T62156-","T62157-","A62158-","A62159-","T62160-","G62161-","A62162-","T62163-","T62164-","G62165-","C62166-","A62167-","T62168-","T62169-","G62170-","T62171-","G62172-","A62173-","A62174-","T62175-","A62176-","T62177-","A62178-","T62179-","C62180-","A62181-","T62182-","T62183-","A62184-","G62185-","G62186-","A62187-","T62188-","T62189-","T62190-","A62191-","A62192-","C62193-","T62194-","C62195-","C62196-","T62197-","T62198-","G62199-","A62200-","C62201-","T62202-","A62203-","T62204-","C62205-","A62206-","T62207-","G62208-","G62209-","C62210-","G62211-","G62212-","T62213-","G62214-","C62215-","C62216-","A62217-","G62218-","A62219-","A62220-","A62221-","T62222-","T62223-","A62224-","C62225-","C62226-","A62227-","T62228-","C62229-","A62230-","A62231-","A62232-","A62233-","G62234-","C62235-","A62236-","T62237-","T62238-","A62239-","A62240-","T62241-","A62242-","C62243-","A62244-","G62245-","T62246-","T62247-","A62248-","T62249-","G62250-","C62251-","A62252-","G62253-","A62254-","T62255-","C62256-","G62257-","C62258-","A62259-","G62260-","T62261-","T62262-","A62263-","G62264-","A62265-","A62266-","C62267-","G62268-","G62269-","T62270-","T62271-","A62272-","T62273-","A62274-","G62275-","C62276-","A62277-","T62278-","C62279-","C62280-","A62281-","C62282-","C62283-","A62284-","T62285-","T62286-","T62287-","A62288-","T62289-","A62290-","T62291-","C62292-","T62293-","A62294-","A62295-","A62303-","T62304-","C62305-","A62306-","A62307-","A62308-","G62309-","A62310-","A62311-","T62312-","A62313-","T62314-","G62315-","T62316-","G62317-","A62318-","C62319-","A62320-","A62321-","C62322-","G62323-","T62324-","C62325-","C62326-","T62327-","A62328-","G62329-","T62330-","T62331-","G62332-","T62333-","A62334-","T62335-","A62336-","C62337-","T62338-","G62339-","A62340-","G62341-","A62342-","A62343-","T62344-","T62345-","G62346-","A62347-","C62348-","G62349-","A62350-","A62351-","A62352-","C62353-","A62354-","A62355-","T62356-","G62357-","T62373-","T62374-","T62375-","C62376-","T62377-","T62378-","A62379-","T62380-","T62381-","A62382-","G62383-","T62384-","A62385-","A62386-","C62387-","C62388-","G62389-","A62390-","C62391-","T62392-","T62393-","A62394-","A62395-","T62396-","A62397-","G62398-","T62399-","A62400-","G62401-","G62402-","A62403-","A62404-","C62405-","T62406-","G62407-","G62408-","A62409-","A62410-","A62411-","A62412-","C62413-","T62414-","A62415-","G62416-","A62417-","C62418-","T62419-","T62420-","G62421-","A62422-","T62423-","T62424-","A62425-","T62426-","T62427-","C62428-","T62429-","A62430-","T62431-","A62432-","A62433-","G62434-","T62435-","A62436-","T62437-","A62438-","G62439-","A62440-","T62441-","A62442-","C62443-","C62444-","C62445-","T62446-","T62447-","C62448-","C62449-","A62450-","A62451-","A62452-","T62453-","A62454-","A62455-","T62456-","G62457-","T62458-","T62459-","C62460-","T62461-","C62462-","T62463-","T62464-","T62465-","G62466-","A62467-","T62468-","A62469-","A62470-","A62471-","A62472-","G62473-","T62474-","T62475-","C62476-","C62477-","A62478-","G62479-","A62480-","A62481-","A62482-","A62483-","T62484-","G62485-","T62486-","A62487-","G62488-","A62489-","A62490-","T62491-","T62492-","T62493-","T62494-","T62495-","T62496-","A62497-","A62498-","A62499-","A62500-","A62501-","G62502-","T62503-","T62504-","A62505-","T62506-","C62507-","T62508-","T62509-","T62510-","T62511-","G62512-","C62513-","T62514-","A62515-","T62516-","T62517-","A62518-","C62519-","T62520-","A62521-","A62522-","T62523-","A62524-","T62525-","C62526-","G62527-","T62528-","G62529-","G62530-","T62531-","T62532-","A62533-","G62534-","A62535-","C62536-","G62537-","C62538-","T62539-","T62540-","A62541-","T62542-","T62543-","A62544-","T62545-","T62546-","A62547-","A62548-","T62549-","A62550-","T62551-","G62552-","A62553-","G62554-","T62555-","G62556-","A62557-","T62558-","G62559-","A62560-","A62561-","A62562-","T62563-","C62564-","C62565-","A62566-","C62567-","A62568-","C62569-","C62570-","G62571-","C62572-","T62573-","T62574-","C62575-","T62576-","A62577-","G62578-","A62579-","T62580-","A62581-","T62582-","C62583-","G62584-","C62585-","T62586-","T62587-","T62588-","T62589-","A62590-","T62591-","T62592-","T62593-","C62594-","C62595-","A62596-","C62597-","A62598-","T62599-","T62600-","A62601-","G62602-","A62603-","T62604-","G62605-","G62606-","T62607-","A62608-","A62609-","A62610-","T62611-","C62612-","C62613-","A62614-","A62615-","T62616-","A62617-","G62618-","T62619-","G62620-","A62621-","A62622-","A62623-","C62624-","T62625-","A62626-","T62627-","C62628-","T62629-","T62630-","T62631-","T62632-","T62633-","A62634-","G62635-","G62636-","A62637-","A62638-","T62639-","G62640-","T62641-","A62642-","T62643-","G62644-","G62645-","A62646-","C62647-","T62648-","C62649-","G62650-","C62651-","G62652-","T62653-","T62654-","T62655-","A62656-","G62657-","A62658-","G62659-","G62660-","A62661-","G62662-","T62663-","G62664-","A62665-","A62666-","C62667-","G62668-","T62669-","C62670-","T62671-","T62672-","C62673-","G62674-","G62675-","A62676-","G62677-","T62678-","A62679-","G62680-","T62681-","A62682-","A62683-","A62684-","G62685-","G62686-","A62687-","T62688-","G62689-","A62690-","T62691-","T62692-","C62693-","G62694-","T62695-","C62696-","A62697-","A62698-","A62699-","T62700-","G62701-","A62702-","A62703-","T62704-","A62705-","A62706-","A62707-","C62708-","A62709-","A62710-","T62711-","T62712-","T62713-","C62714-","A62715-","C62716-","A62717-","A62718-","A62719-","T62720-","G62721-","G62722-","A62723-","T62724-","G62725-","T62726-","T62727-","A62728-","A62729-","T62730-","G62731-","T62732-","A62733-","T62734-","T62735-","A62736-","G62737-","T62738-","A62739-","G62740-","G62741-","A62742-","A62743-","A62744-","T62745-","T62746-","T62747-","T62748-","T62749-","T62750-","G62751-","A62752-","C62753-","G62754-","C62755-","T62756-","A62757-","G62758-","T62759-","G62760-","G62761-","A62762-","A62763-","T62764-","T62765-","G62766-","A62767-","A62768-","G62769-","A62770-","T62771-","T62772-","C62773-","T62774-","A62775-","A62776-","T62777-","G62778-","G62779-","A62780-","T62781-","G62782-","A62783-","T62784-","G62785-","T62786-","T62787-","C62788-","T62789-","A62790-","C62791-","C62792-","T62793-","A62794-","T62795-","T62796-","T62797-","C62798-","A62799-","T62800-","C62801-","C62802-","G62803-","A62804-","T62805-","A62806-","A62807-","C62808-","A62809-","T62810-","G62811-","T62812-","T62813-","A62814-","A62815-","T62816-","T62817-","T62818-","C62819-","C62820-","A62821-","A62822-","T62823-","A62824-","C62825-","C62826-","A62827-","A62828-","C62829-","G62830-","G62831-","T62832-","T62833-","T62834-","T62835-","A62836-","A62837-","T62838-","A62839-","T62840-","T62841-","T62842-","C62843-","G62844-","A62845-","T62846-","G62847-","A62848-","T62849-","A62850-","T62851-","A62852-","C62853-","G62854-","G62855-","T62856-","A62857-","G62858-","T62859-","C62860-","T62863-","C62864-","T62865-","T62866-","T62867-","C62868-","G62869-","G62870-","A62871-","C62872-","T62873-","T62874-","A62875-","T62876-","A62877-","T62878-","A62879-","G62880-","C62881-","T62882-","T62883-","A62884-","T62885-","T62886-","C62887-","C62888-","A62889-","C62890-","A62891-","A62892-","T62893-","A62894-","C62895-","G62896-","A62897-","G62898-","T62899-","C62900-","A62901-","T62902-","T62903-","A62904-","T62905-","A62906-","T62907-","A62908-","C62909-","T62910-","C62911-","C62912-","A62913-","A62914-","A62915-","A62916-","A62917-","A62918-","C62919-","A62920-","A62921-","A62922-","A62923-","T62924-","A62925-","A62926-","C62927-","T62928-","A62929-","G62930-","T62931-","A62932-","T62933-","A62934-","A62935-","A62936-","A62937-","T62938-","C62939-","T62940-","G62941-","T62942-","A62943-","T62944-","C62945-","G62946-","A62947-","A62948-","T62949-","G62950-","G62951-","G62952-","A62953-","A62954-","A62955-","A62956-","A62957-","C62958-","G62959-","A62960-","A62961-","A62962-","T62963-","T62964-","A62965-","T62966-","C62967-","G62968-","A62969-","T62970-","A62971-","T62972-","A62973-","G62974-","G62975-","T62976-","A62977-","T62978-","A62979-","G62980-","A62981-","A62982-","T62983-","C62984-","C62985-","G62986-","G62987-","A62988-","A62989-","C62990-","A62991-","T62992-","T62993-","G62994-","A62995-","A62996-","C62997-","G62998-","T62999-","A63000-","T63001-","T63002-","A63003-","A63004-","T63005-","A63006-","C63007-","T63008-","T63009-","A63010-","A63011-","T63012-","T63013-","C63014-","T63015-","T63016-","T63017-","T63018-","T63019-","C63020-","A63021-","G63022-","T63023-","G63024-","G63025-","T63026-","A63027-","A63028-","G63029-","A63030-","A63031-","C63032-","C63033-","G63034-","A63035-","T63036-","A63037-","G63038-","G63039-","T63040-","T63041-","A63042-","T63043-","T63044-","G63045-","A63046-","C63047-","A63048-","T63049-","T63050-","G63051-","T63052-","A63053-","T63054-","G63055-","G63056-","T63057-","T63058-","T63059-","T63060-","A63061-","A63062-","A63063-","T63064-","A63065-","T63066-","T63067-","C63068-","T63069-","A63070-","T63071-","A63072-","A63073-","C63074-","T63075-","T63076-","G63077-","A63078-","G63079-","A63080-","C63081-","T63082-","T63083-","G63084-","A63085-","T63086-","A63087-","G63088-","A63089-","T63090-","A63091-","T63092-","T63093-","A63094-","A63095-","T63096-","G63097-","A63098-","C63099-","G63100-","A63101-","A63102-","T63103-","T63104-","G63105-","A63106-","A63107-","A63108-","A63109-","T63110-","T63111-","A63112-","T63113-","T63114-","T63115-","T63116-","T63117-","A63118-","T63119-","C63120-","A63121-","C63122-","C63123-","A63124-","C63125-","G63126-","T63127-","G63128-","T63129-","G63130-","T63131-","T63132-","T63133-","C63134-","A63135-","G63136-","G63137-","A63138-","T63139-","C63140-","A63141-","T63142-","C63143-","G63144-","T63145-","C63146-","G63147-","A63148-","C63149-","G63150-","C63151-","C63152-","A63153-","G63154-","T63155-","T63156-","A63157-","A63158-","C63159-","C63160-","A63161-","A63162-","C63163-","C63164-","G63165-","A63166-","A63167-","T63168-","G63169-","G63170-","A63171-","G63172-","T63173-","A63174-","A63175-","A63176-","A63177-","T63178-","A63179-","A63180-","A63181-","T63182-","A63183-","T63184-","C63185-","A63186-","T63187-","T63188-","A63189-","A63190-","T63191-","A63192-","T63193-","A63194-","T63195-","G63196-","C63197-","T63198-","C63199-","T63200-","A63201-","G63202-","A63203-","T63204-","A63205-","T63206-","T63207-","A63208-","G63209-","T63210-","A63211-","T63212-","T63213-","T63214-","T63215-","T63216-","A63217-","T63218-","T63219-","A63220-","A63221-","T63222-","C63223-","C63224-","T63225-","T63226-","T63227-","G63228-","A63229-","T63230-","T63231-","A63232-","T63233-","C63234-","A63235-","T63236-","C63237-","T63238-","T63239-","C63240-","T63241-","C63242-","G63243-","T63244-","A63245-","C63246-","G63247-","C63248-","G63249-","A63250-","A63251-","T63252-","G63253-","A63254-","T63255-","T63256-","C63257-","C63258-","A63259-","T63260-","G63261-","A63262-","T63263-","C63264-","A63265-","A63266-","G63267-","A63268-","G63269-","T63270-","G63271-","A63272-","T63273-","T63274-","T63275-","G63276-","A63277-","G63278-","A63279-","A63280-","C63281-","A63282-","T63283-","C63284-","C63285-","T63286-","C63287-","C63288-","G63289-","G63290-","A63291-","G63292-","T63293-","A63294-","T63295-","T63296-","A63297-","A63298-","T63299-","G63300-","G63301-","G63302-","T63303-","T63304-","T63305-","A63306-","G63307-","T63308-","A63309-","A63310-","A63311-","C63312-","A63313-","G63314-","T63315-","C63316-","C63317-","A63318-","T63319-","C63320-","G63321-","T63322-","T63323-","G63324-","C63325-","A63326-","A63327-","T63328-","A63329-","A63330-","T63331-","A63332-","A63333-","A63334-","A63335-","G63336-","T63337-","T63338-","G63339-","T63340-","C63341-","C63342-","A63343-","A63344-","G63345-","T63346-","T63347-","A63348-","A63349-","A63350-","G63351-","G63352-","A63353-","T63354-","A63355-","T63356-","T63357-","A63358-","T63359-","G63360-","C63361-","A63362-","T63363-","T63364-","C63365-","G63366-","T63367-","T63368-","T63369-","A63370-","A63371-","A63372-","G63373-","A63374-","T63375-","A63376-","T63377-","C63378-","A63379-","C63380-","C63381-","T63382-","C63383-","A63384-","T63385-","C63386-","T63387-","A63388-","A63389-","C63390-","G63391-","G63392-","A63393-","G63394-","A63395-","C63396-","A63397-","A63398-","T63399-","T63400-","T63401-","T63402-","T63403-","T63404-","G63405-","G63406-","T63407-","A63408-","G63409-","G63410-","T63411-","T63412-","T63413-","T63414-","A63415-","G63416-","A63417-","G63418-","A63419-","C63420-","T63421-","T63422-","T63423-","G63424-","A63425-","A63426-","G63427-","C63428-","T63429-","A63430-","C63431-","T63432-","T63433-","G63434-","T63435-","T63436-","T63437-","A63438-","A63439-","C63440-","A63441-","A63442-","A63443-","G63444-","T63445-","T63446-","A63447-","T63448-","T63449-","C63450-","A63451-","T63452-","C63453-","G63454-","T63455-","C63456-","G63457-","T63458-","C63459-","T63460-","A63461-","C63462-","T63463-","A63464-","T63465-","T63466-","C63467-","T63468-","A63469-","T63470-","T63471-","T63472-","A63473-","A63474-","T63475-","T63476-","T63477-","T63478-","G63479-","T63480-","A63481-","G63482-","T63483-","T63484-","A63485-","A63486-","T63487-","T63488-","T63489-","A63490-","T63491-","C63492-","A63493-","C63494-","A63495-","T63496-","A63497-","T63498-","C63499-","A63500-","C63501-","A63502-","T63503-","T63504-","A63505-","A63506-","A89103-","A89104-","A89105-","G89148-","T89149-","C89150-","A89151-","T89166-","C89229-","A89230-","G89231-","T89232-","G89233-","T89234-","T89235-","A89373-","C89374-","T89375-","T89376-","A89377-","T89378-","A89379-","T89380-","T89381-","C89382-","G89383-","T89384-","G89385-","T89386-","C89387-","T89388-","A89389-","G89390-","T89391-","A89392-","G89393-","A89394-","T89700-","A194548-","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","C194595-","G194596-","T194597-","G194598-","T194599-"],"OPG002":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-"],"OPG002_dup":["C44-","L45-","S46-","C47-"],"OPG057":["N267D"],"OPG082":["T259-","P260-","K261-","T262-","F263-","T264-","P265-","L266-","N267-","A268-","S269-","P270-","V277-","F328-","I329-","K330-","E331-","N332-","I333-","I334-","W335-","K336-","G337-","I338-","Y339-","T340-","F348-","P349-","V350-","P351-","T352-","T357-","N358-","K359-","K360-","K361-","V369-","N370-","S371-","Q372-"]},"labels":{"aa":"OPG002: K31-, C32-, K33-, D34-, N35-, E36-, Y37-; OPG002_dup: C44-, L45-, S46-, C47-; OPG057: N267D; OPG082: T259-, P260-, K261-, T262-, F263-, T264-, P265-, L266-, N267-, A268-, S269-, P270-, V277-, F328-, I329-, K330-, E331-, N332-, I333-, I334-, W335-, K336-, G337-, I338-, Y339-, T340-, F348-, P349-, V350-, P351-, T352-, T357-, N358-, K359-, K360-, K361-, V369-, N370-, S371-, Q372-"}},"children":[{"name":"OQ672577","node_attrs":{"div":7,"accession":"OQ672577","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"strain_display":{"value":"Belgium/OQ672577/2023-02-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2023-02-13"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"13022023_anal"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-61794G","-61795G","-61796C","-61797A","-61798T","-61815A","-61816G","-61817T","-61818A","-61819C","-61820A","-61821A","-61822G","-61823T","-61824G","-61825G","-61826C","-61827T","-61828G","-61829C","-61830T","-61831A","-61832T","-61833T","-61834T","-61835C","-61836G","-61837G","-61838C","-61839T","-61840G","-61841C","-61842C","-61843A","-61844G","-61845A","-61846G","-61847T","-61848G","-61849T","-61850C","-61851C","-61852A","-61853A","-61854T","-61855T","-61856C","-61857T","-61858A","-61859C","-61860C","-61861G","-61862T","-61863T","-61864G","-61865T","-61866T","-61867A","-61868C","-61869T","-61870C","-61871C","-61872A","-61873T","-61874T","-61875A","-61876T","-61877A","-61878T","-61879A","-61880T","-61881T","-61882C","-61883C","-61884T","-61885T","-61886G","-61887A","-61888A","-61889T","-61890A","-61891A","-61892C","-61893C","-61894T","-61895T","-61896C","-61897A","-61898T","-61899A","-61900G","-61901C","-61902T","-61903A","-61904T","-61905T","-61906T","-61907T","-61908A","-61909A","-61910T","-61911A","-61912G","-61913G","-61914A","-61915T","-61916C","-61917T","-61918A","-61919T","-61920A","-61921T","-61922G","-61923A","-61924T","-61925C","-61926A","-61927G","-61928T","-61929G","-61930T","-61931T","-61932T","-61933A","-61934A","-61935G","-61936C","-61937C","-61938A","-61939T","-61940A","-61941G","-61942C","-61943A","-61944C","-61945A","-61946A","-61947T","-61948T","-61949T","-61950T","-61951C","-61952T","-61953A","-61954A","-61955T","-61956A","-61957C","-61958G","-61961A","-61962C","-61963G","-61964T","-61965G","-61966A","-61967T","-61968T","-61969T","-61970T","-61971A","-61972T","-61973C","-61974A","-61975A","-61976A","-61977C","-61978A","-61979T","-61980G","-61981A","-61982C","-61983A","-61984T","-61985T","-61986T","-61987T","-61988C","-61989C","-61990T","-61991T","-61992G","-61993T","-61994A","-61995T","-61996C","-61997C","-61998A","-61999T","-62000T","-62001T","-62002C","-62003G","-62004T","-62005T","-62006T","-62007A","-62008A","-62009T","-62010G","-62011A","-62012C","-62013A","-62014A","-62015A","-62016C","-62017A","-62018T","-62019T","-62020T","-62021T","-62022T","-62023G","-62024T","-62025T","-62026G","-62027G","-62028T","-62029G","-62030T","-62031A","-62032A","-62033T","-62034A","-62035A","-62036A","-62037A","-62038A","-62039A","-62040A","-62041A","-62042T","-62043T","-62044A","-62045T","-62046T","-62047T","-62048A","-62049A","-62050T","-62051T","-62052T","-62053T","-62054T","-62055C","-62056A","-62057T","-62058T","-62059A","-62060A","-62061T","-62062A","-62064G","-62066A","-62067T","-62068T","-62069T","-62070G","-62071A","-62072C","-62073G","-62074T","-62075A","-62076T","-62077G","-62078T","-62079A","-62080G","-62081C","-62082G","-62083T","-62084A","-62085C","-62086A","-62087A","-62088A","-62089A","-62090T","-62091T","-62092A","-62093T","-62094C","-62095G","-62096T","-62097T","-62098C","-62099C","-62100T","-62101G","-62102G","-62103T","-62104A","-62105T","-62106A","-62107T","-62108A","-62109G","-62110A","-62111T","-62112A","-62113A","-62114A","-62115G","-62116A","-62117G","-62118T","-62119C","-62120C","-62121T","-62122A","-62123T","-62124A","-62125T","-62126A","-62127T","-62128T","-62129T","-62130G","-62131A","-62132A","-62133A","-62134A","-62135T","-62136C","-62137G","-62138T","-62139T","-62140A","-62141C","-62142G","-62143G","-62144T","-62145T","-62146C","-62147G","-62148A","-62149T","-62150T","-62151A","-62152A","-62153A","-62154C","-62155T","-62156T","-62157T","-62158A","-62159A","-62160T","-62161G","-62162A","-62163T","-62164T","-62165G","-62166C","-62167A","-62168T","-62169T","-62170G","-62171T","-62172G","-62173A","-62174A","-62175T","-62176A","-62177T","-62178A","-62179T","-62180C","-62181A","-62182T","-62183T","-62184A","-62185G","-62186G","-62187A","-62188T","-62189T","-62190T","-62191A","-62192A","-62193C","-62194T","-62195C","-62196C","-62197T","-62198T","-62199G","-62200A","-62201C","-62202T","-62203A","-62204T","-62205C","-62206A","-62207T","-62208G","-62209G","-62210C","-62211G","-62212G","-62213T","-62214G","-62215C","-62216C","-62217A","-62221A","-62222T","-62223T","-62228T","-62229C","-62230A","-62231A","-62232A","-62233A","-62234G","-62235C","-62236A","-62237T","-62238T","-62239A","-62240A","-62241T","-62242A","-62243C","-62244A","-62245G","-62246T","-62247T","-62248A","-62249T","-62250G","-62251C","-62252A","-62253G","-62254A","-62255T","-62256C","-62257G","-62258C","-62259A","-62260G","-62264G","-62265A","-62266A","-62267C","-62268G","-62269G","-62270T","-62271T","-62272A","-62273T","-62274A","-62275G","-62276C","-62277A","-62278T","-62279C","-62280C","-62281A","-62282C","-62283C","-62284A","-62285T","-62286T","-62287T","-62288A","-62289T","-62290A","-62303A","-62304T","-62309G","-62310A","-62311A","-62312T","-62313A","-62314T","-62315G","-62316T","-62317G","-62318A","-62319C","-62320A","-62321A","-62322C","-62324T","-62325C","-62326C","-62327T","-62328A","-62329G","-62330T","-62331T","-62332G","-62333T","-62352A","-62353C","-62354A","-62355A","-62356T","-62357G","-62389G","-62390A","-62391C","-62392T","-62393T","-62413C","-62414T","-62416G","-62417A","-62420T","-62421G","-62422A","-62423T","-62424T","-62425A","-62426T","-62427T","-62428C","-62429T","-62430A","-62431T","-62432A","-62474T","-62475T","-62484T","-62492T","-62493T","-62494T","-62495T","-62496T","-62497A","-62498A","-62499A","-62500A","-62501A","-62502G","-62503T","-62504T","-62505A","-62506T","-62507C","-62508T","-62509T","-62510T","-62511T","-62512G","-62513C","-62514T","-62515A","-62516T","-62517T","-62518A","-62519C","-62520T","-62521A","-62522A","-62523T","-62524A","-62525T","-62526C","-62527G","-62528T","-62529G","-62530G","-62531T","-62532T","-62543T","-62546T","-62547A","-62548A","-62549T","-62550A","-62551T","-62552G","-62553A","-62554G","-62555T","-62556G","-62557A","-62558T","-62559G","-62560A","-62561A","-62562A","-62563T","-62564C","-62565C","-62566A","-62567C","-62568A","-62569C","-62570C","-62571G","-62572C","-62573T","-62575C","-62579A","-62580T","-62581A","-62582T","-62583C","-62584G","-62585C","-62586T","-62587T","-62588T","-62589T","-62590A","-62591T","-62592T","-62593T","-62594C","-62595C","-62596A","-62597C","-62598A","-62599T","-62600T","-62601A","-62602G","-62606G","-62607T","-62608A","-62609A","-62610A","-62611T","-62612C","-62616T","-62617A","-62618G","-62619T","-62620G","-62621A","-62627T","-62632T","-62633T","-62634A","-62635G","-62636G","-62637A","-62638A","-62639T","-62640G","-62641T","-62642A","-62643T","-62653T","-62694G","-62695T","-62697A","-62698A","-62700T","-62705A","-62706A","-62707A","-62708C","-62709A","-62710A","-62711T","-62712T","-62713T","-62714C","-62715A","-62716C","-62717A","-62718A","-62719A","-62720T","-62721G","-62722G","-89103A","-89104A","-89105A","-89148G","-89149T","-89150C","-89151A","-89229C","-89230A","-89231G","-89232T","-89233G","-89234T","-89235T","-89373A","-89374C","-89375T","-89376T","-89377A","-89378T","-89379A","-89380T","-89381T","-89382C","-89383G","-89384T","-89385G","-89386T","-89387C","-89388T","-89389A","-89390G","-89391T","-89392A","-89393G","-89394A","-89700T","C194600-","C194601-","T194602-"],"OPG002_dup":["P48-"]},"labels":{"aa":"OPG002_dup: P48-"}}},{"name":"OQ672579","node_attrs":{"div":7,"accession":"OQ672579","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"strain_display":{"value":"Belgium/OQ672579/2023-02-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2023-02-28"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"28022023_anal"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-62294A","-62374T","-62375T","-63506A","C70785-","G70786-","T70787-","A70788-","T70789-","A70790-","T70829-","C70830-","G70880-","T70881-","G70882-","C70883-","C70884-","G70885-","T70886-","T70887-","A70888-","C70889-","C70890-","C70891-","T70892-","G70893-","C70894-","C70895-","G70907-","C70908-","A70909-","T70910-","T70911-","A70912-","G70913-","A70914-","A70915-","C70916-","C70917-","A70918-","C70919-","G70920-","T70921-","G70940-","A70941-","A70942-","T70963-","T70970-","T70971-","C70972-","G70973-","A70974-","A70975-","A70976-","A70977-","T70978-","A70979-","C70980-","T70981-","A70982-","A70983-","A70984-","T70985-","C70986-","A70987-","T71023-","G71024-","G71025-","A71026-","T71027-","A71028-","T71029-","T71030-","C71031-","T71032-","A71033-","A71034-","C71035-","G71036-","A71037-","A71038-","A71039-","A71040-","C71041-","T71042-","G71043-","T71044-","A71045-","A71046-","C71047-","A71048-","C71049-","C71050-","A71051-","T71052-","A71053-","G71054-","T71055-","G71056-","T71057-","T71058-","C71059-","G71060-","G71061-","C71062-","A71063-","T71064-","C71065-","T71066-","A71067-","T71068-","A71069-","A71070-","G71071-","G71072-","A71073-","T71074-","A71075-","A71076-","T71077-","T71078-","T71079-","A71080-","C71081-","T71082-","A71083-","C71084-","T71085-","G71086-","A71087-","G71088-","T71089-","A71090-","T71091-","A71092-","A71129-","C71130-","C71131-","A71132-","A71133-","T71134-","A71135-","C71136-","T71137-","A71138-","A71139-","A71140-","A71141-","G71142-","T71143-","G71144-","A71145-","T71146-","A71147-","A71148-","T71149-","A71150-","T71172-","T71173-","A71174-","A71175-","A71176-","A71177-","A71178-","A71179-","T71180-","G71181-","G71182-","T71183-","G71184-","T71185-","T71186-","C71187-","C71188-","A71189-","G71190-","C71191-","T71192-","C71193-","G71194-","T71195-","G71196-","T71197-","G71198-","T71199-","T71200-","C71201-","T71202-","A71203-","C71204-","A71205-","T71206-","G71207-","C71208-","G71209-","G71210-","C71211-","A71212-","A71213-","A71214-","G71215-","A71216-","T71217-","A71218-","T71219-","T71220-","T71221-","C71222-","T71223-","C71224-","A71225-","C71226-","G71227-","A71228-","A71229-","C71230-","G71231-","A71232-","T71233-","A71234-","T71235-","A71236-","A71237-","A71238-","T71239-","T71240-","G71241-","A71242-","T71243-","T71244-","A71245-","T71246-","A71247-","C71248-","G71249-","A71250-","A71251-","A71252-","A71253-","A71254-","A71255-","A71256-","T71257-","C71258-","A71259-","T71260-","T71261-","A71262-","A71263-","A71264-","G71265-","G71266-","A71267-","T71268-","G71269-","T71270-","A71271-","C71272-","T71273-","A71274-","G71275-","T71276-","C71277-","A71278-","G71279-","T71280-","G71281-","T71282-","A71283-","A71284-","A71285-","G71286-","A71287-","A71288-","C71289-","G71290-","A71291-","A71292-","T71293-","G71294-","T71295-","T71296-","G71297-","T71298-","A71299-","G71300-","G71301-","T71302-","T71303-","A71304-","A71305-","A71306-","A71307-","T71308-","T71309-","A71310-","T71311-","C71312-","T71313-","A71314-","C71315-","A71316-","C71317-","A71318-","A71319-","A71320-","T71321-","A71322-","G71323-","A71324-","A71325-","C71326-","C71327-","T71328-","C71329-","A71330-","A71331-","C71332-","G71333-","T71334-","A71335-","A71336-","C71337-","T71338-","T71339-","A71340-","A71341-","C71342-","A71343-","G71344-","T71345-","G71346-","C71347-","A71348-","A71349-","C71350-","C71351-","T71352-","C71353-","T71354-","A71355-","T71356-","T71357-","G71358-","G71359-","A71360-","T71361-","A71362-","T71363-","A71364-","A71365-","A71366-","C71367-","T71368-","A71369-","A71370-","T71371-","G71372-","G71373-","A71374-","T71375-","C71376-","C71377-","G71378-","G71379-","T71380-","T71381-","A71382-","A71383-","T71384-","T71385-","T71386-","T71387-","A71388-","T71389-","C71390-","A71391-","A71392-","G71393-","A71394-","C71395-","A71396-","T71397-","A71398-","T71399-","G71400-","C71401-","G71402-","C71403-","C71404-","T71405-","A71406-","G71407-","A71408-","G71409-","G71410-","T71411-","T71412-","C71413-","T71414-","A71415-","T71416-","T71417-","A71418-","T71419-","T71420-","T71421-","T71422-","T71423-","A71424-","T71425-","T71426-","G71517-","T71518-","A71519-","G71520-","T71521-","T71522-","G71523-","A71524-","A71525-","T71526-","C71527-","T71528-","A71529-","C71530-","C71531-","T71532-","A71533-","T71534-","A71535-","G71536-","A71537-","A71538-","A71539-","A71540-","G71541-","G71542-","A71543-","G71544-","T71545-","T71546-","A71547-","G71548-","A71549-","A71550-","T71551-","A71552-","G71553-","T71554-","C71555-","C71556-","C71557-","A71558-","T71559-","T71560-","G71561-","G71562-","A71563-","T71564-","A71565-","G71566-","A71567-","T71568-","T71569-","T71570-","T71571-","T71572-","T71573-","G71574-","A71575-","A71576-","G71577-","G71578-","A71579-","T71580-","A71581-","T71582-","C71583-","T71584-","T71585-","A71586-","G71587-","T71588-","G71589-","C71590-","A71591-","A71592-","A71593-","A71594-","G71595-","T71596-","A71597-","T71598-","A71599-","C71600-","A71601-","T71602-","G71603-","T71604-","T71605-","A71606-","G71607-","A71608-","G71609-","A71610-","A71611-","T71612-","A71613-","T71614-","T71615-","C71616-","A71617-","A71618-","G71619-","T71620-","T71621-","A71622-","T71623-","G71624-","A71625-","A71626-","A71627-","A71628-","T71629-","A71630-","G71631-","C71632-","A71633-","G71634-","C71635-","T71636-","G71637-","A71638-","T71639-","A71640-","T71641-","G71642-","T71643-","C71644-","G71645-","T71646-","T71647-","A71648-","A71649-","C71650-","T71651-","T71652-","G71676-","G71677-","T71678-","C71679-","G71709-","C71710-","T71711-","G71712-","A71713-","A71714-","T71715-","G71716-","T71717-","T71718-","A71719-","T71720-","A71721-","A71722-","A71723-","A71724-","A71725-","T71726-","G71727-","C71728-","C71729-","G71730-","G71731-","T71732-","A71733-","T71734-","T71735-","G71736-","A71737-","T71738-","A71739-","C71740-","A71741-","T71742-","C71743-","G71744-","T71745-","C71746-","T71747-","A71748-","A71749-","A71750-","C71751-","G71752-","A71753-","A71754-","T71755-","A71756-","T71757-","T71758-","A71759-","G71760-","G71761-","T71762-","A71763-","A71764-","A71765-","G71766-","A71767-","T71768-","A71769-","T71770-","T71771-","T71772-","T71773-","T71774-","C71775-","T71776-","G71777-","A71778-","G71779-","C71780-","C71781-","A71782-","A71783-","A71784-","A71785-","C71786-","T71787-","T71788-","T71789-","A71790-","C71791-","A71792-","G71793-","A71794-","T71795-","G71796-","A71797-","T71798-","A71799-","A71800-","T71801-","A71802-","G71803-","A71804-","T71805-","G71806-","G71807-","A71808-","T71809-","A71810-","A71811-","A71812-","G71813-","C71856-","C71910-","T71911-","T71912-","T71913-","T71914-","T71915-","C71916-","T71917-","T71918-","A71919-","A71920-","C71921-","G71922-","T71923-","T71924-","G71925-","T71926-","T71927-","T71928-","G71929-","C71930-","C71931-","A71932-","T71933-","C71934-","A71935-","C71936-","T71937-","C71938-","T71939-","C71940-","A71941-","T71942-","A71943-","A71944-","T71945-","G71946-","T71947-","A71948-","A71949-","A71950-","G71951-","A71952-","T71953-","A71954-","T71955-","T71956-","C71957-","T71958-","A71959-","A71960-","A71961-","A71962-","T71963-","G71964-","G71965-","T71966-","A71967-","A71968-","A71969-","C71970-","T71971-","T71972-","T71973-","T71974-","G71975-","C71976-","A71977-","T71978-","A71979-","T71980-","C71981-","G71982-","G71983-","A71984-","T71985-","G71986-","C71987-","A71988-","G71989-","A71990-","A71991-","A71992-","T71993-","T71994-","G71995-","G71996-","T71997-","A71998-","T71999-","A72000-","A72001-","A72002-","T72003-","G72004-","T72005-","T72006-","G72007-","T72008-","A72009-","A72010-","T72011-","T72012-","G72013-","T72014-","A72015-","T72016-","T72017-","A72018-","T72019-","T72020-","T72021-","C72022-","C72023-","C72024-","G72025-","T72026-","C72027-","A72028-","A72029-","T72030-","G72031-","G72032-","A72033-","C72034-","T72035-","A72036-","G72037-","T72038-","C72039-","A72040-","C72041-","A72042-","G72043-","C72044-","T72045-","C72046-","C72047-","A72048-","T72049-","C72050-","A72051-","G72052-","T72053-","T72054-","T72055-","T72056-","A72057-","T72058-","A72059-","T72060-","C72061-","C72062-","T72063-","T72064-","T72065-","A72066-","G72067-","A72068-","G72069-","T72070-","A72071-","T72072-","T72073-","T72074-","C72075-","T72076-","C72077-","A72078-","C72079-","T72080-","C72081-","G72082-","T72083-","G72084-","T72085-","C72086-","T72087-","A72088-","G72089-","C72090-","A72091-","T72092-","T72093-","C72094-","T72095-","A72096-","G72097-","A72098-","G72099-","C72100-","A72101-","T72102-","T72103-","C72104-","C72105-","A72106-","T72107-","G72108-","A72109-","T72110-","C72111-","T72112-","G72113-","T72114-","T72115-","T72116-","A72117-","T72118-","C72119-","G72120-","T72121-","T72122-","G72123-","A72124-","T72125-","A72126-","T72127-","T72128-","G72129-","G72130-","C72131-","C72132-","G72133-","G72134-","A72135-","A72136-","A72137-","G72138-","A72139-","T72140-","A72141-","G72142-","A72143-","T72144-","T72145-","T72146-","T72147-","T72148-","T72149-","A72150-","T72151-","T72152-","T72153-","T72154-","T72155-","T72156-","A72157-","T72158-","T72159-","A72160-","T72161-","A72162-","T72163-","T72164-","A72165-","C72166-","T72167-","A72168-","T72169-","T72170-","G72171-","G72172-","C72173-","A72174-","A72175-","T72176-","T72177-","G72178-","T72179-","A72180-","G72181-","A72182-","T72183-","A72184-","T72185-","A72186-","A72187-","C72188-","T72189-","T72190-","C72191-","T72192-","G72193-","G72194-","T72195-","A72196-","A72197-","A72198-","T72199-","A72200-","T72201-","T72202-","T72203-","T72204-","T72205-","C72206-","T72207-","A72208-","C72209-","C72210-","T72211-","T72212-","T72213-","T72214-","C72215-","A72216-","A72217-","T72218-","C72219-","T72220-","C72221-","T72222-","T72223-","C72224-","T72225-","A72226-","T72227-","T72228-","T72229-","T72230-","C72231-","A72232-","A72233-","G72234-","C72235-","C72236-","G72237-","G72238-","C72239-","T72240-","A72241-","T72242-","A72243-","T72244-","A72245-","T72246-","T72247-","C72248-","T72249-","G72250-","C72251-","T72252-","A72253-","T72254-","A72255-","T72256-","T72257-","G72258-","T72259-","T72260-","A72261-","C72262-","T72263-","A72264-","G72265-","T72266-","A72267-","T72268-","C72269-","A72270-","A72271-","T72272-","A72273-","C72274-","C72275-","T72276-","T72277-","T72278-","T72279-","C72280-","T72281-","G72282-","G72283-","C72284-","T72285-","A72286-","A72287-","G72288-","A72289-","A72290-","G72291-","T72292-","C72293-","A72294-","T72295-","A72296-","T72297-","G72298-","T72299-","G72300-","G72301-","T72302-","A72303-","T72304-","T72305-","C72306-","A72307-","C72308-","T72309-","A72310-","T72311-","A72312-","T72313-","C72314-","A72315-","G72316-","T72317-","T72318-","T72319-","T72320-","A72321-","A72322-","C72323-","T72324-","G72325-","G72326-","T72327-","A72328-","G72329-","T72330-","T72331-","C72332-","C72333-","A72334-","T72335-","T72336-","A72337-","G72338-","C72339-","C72340-","T72341-","T72342-","T72343-","C72344-","C72345-","A72346-","C72347-","T72348-","T72349-","C72350-","T72351-","G72352-","C72353-","A72354-","G72355-","A72356-","A72357-","T72358-","A72359-","A72360-","T72361-","T72362-","A72363-","G72364-","A72365-","A72366-","A72367-","T72368-","T72369-","G72370-","G72371-","T72372-","T72373-","C72374-","T72375-","T72376-","T72377-","A72378-","C72379-","C72380-","A72381-","G72382-","A72383-","A72384-","A72385-","A72386-","T72387-","C72388-","C72389-","A72390-","G72391-","C72392-","T72393-","A72394-","-194548A","-194549A"],"OPG080":["A75-"],"OPG089":["S307F","I309-","P310-","S322-","V339-","P340-","L341-","P342-","C343-","Q344-","L349-","E350-","P351-","R352-","K353-","E359-"],"OPG091":["L163-"],"OPG092":["A186-","G187-","F188-","S189-","G190-","K191-","E192-","P193-","I194-","S195-","N196-","Y197-","S198-","A199-","E200-","V201-","E202-","R203-","L204-","M205-","E206-","L207-","P208-","V209-","K210-","T211-","D212-","I213-","V214-","N215-","T216-","T217-","Y218-","D219-","F220-","L221-","A222-","R223-","K224-","G225-","I226-","D227-","T228-","S229-","N230-","N231-","I232-","A233-","E234-","Y235-","I236-","A237-","G238-","L239-","K240-","I241-","E242-","E243-","I244-","E245-","K246-","V247-","E248-","K249-","Y250-","L251-","P252-","E253-","V254-","I255-","S256-","T257-","I258-","A259-","N260-","S261-","N262-","I263-","I264-","K265-","N266-","K267-","K268-","S269-","I270-","F271-","P272-","A273-","N274-","I275-","N276-","D277-","K278-","Q279-","I280-","M281-","E282-","C283-","S284-","R285-","M286-","L287-","D288-","T289-","S290-","E291-","K292-","Y293-","S294-","K295-","G296-","Y297-","K298-","T299-","D300-","G301-","A302-","V303-","T304-","S305-","P306-","L307-","T308-","G309-","N310-","N311-","T312-","I313-","T314-","T315-","F316-","I317-","P318-","I319-","S320-","A321-","S322-","D323-","M324-","Q325-","K326-","F327-","T328-","I329-","L330-","E331-","Y332-","L333-","Y334-","I335-","M336-","R337-","V338-","M339-","A340-","N341-","N342-","V343-","K344-","K345-","K346-","V365-"],"OPG109":["L19-","L20-","D21-","T22-","N23-","I24-","S25-","D100-"]},"labels":{"aa":"OPG080: A75-; OPG089: S307F, I309-, P310-, S322-, V339-, P340-, L341-, P342-, C343-, Q344-, L349-, E350-, P351-, R352-, K353-, E359-; OPG091: L163-; OPG092: A186-, G187-, F188-, S189-, G190-, K191-, E192-, P193-, I194-, S195-, N196-, Y197-, S198-, A199-, E200-, V201-, E202-, R203-, L204-, M205-, E206-, L207-, P208-, V209-, K210-, T211-, D212-, I213-, V214-, N215-, T216-, T217-, Y218-, D219-, F220-, L221-, A222-, R223-, K224-, G225-, I226-, D227-, T228-, S229-, N230-, N231-, I232-, A233-, E234-, Y235-, I236-, A237-, G238-, L239-, K240-, I241-, E242-, E243-, I244-, E245-, K246-, V247-, E248-, K249-, Y250-, L251-, P252-, E253-, V254-, I255-, S256-, T257-, I258-, A259-, N260-, S261-, N262-, I263-, I264-, K265-, N266-, K267-, K268-, S269-, I270-, F271-, P272-, A273-, N274-, I275-, N276-, D277-, K278-, Q279-, I280-, M281-, E282-, C283-, S284-, R285-, M286-, L287-, D288-, T289-, S290-, E291-, K292-, Y293-, S294-, K295-, G296-, Y297-, K298-, T299-, D300-, G301-, A302-, V303-, T304-, S305-, P306-, L307-, T308-, G309-, N310-, N311-, T312-, I313-, T314-, T315-, F316-, I317-, P318-, I319-, S320-, A321-, S322-, D323-, M324-, Q325-, K326-, F327-, T328-, I329-, L330-, E331-, Y332-, L333-, Y334-, I335-, M336-, R337-, V338-, M339-, A340-, N341-, N342-, V343-, K344-, K345-, K346-, V365-; OPG109: L19-, L20-, D21-, T22-, N23-, I24-, S25-, D100-"}}},{"name":"OQ672576","node_attrs":{"div":8,"accession":"OQ672576","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"strain_display":{"value":"Belgium/OQ672576/2023-02-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2023-02-08"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"08022023_anal"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T70389G","-194548A"],"OPG089":["M175R"]},"labels":{"aa":"OPG089: M175R"}}},{"name":"OQ672578","node_attrs":{"div":7,"accession":"OQ672578","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"strain_display":{"value":"Belgium/OQ672578/2023-02-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2023-02-23"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"23022023_anal"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T2662-","C47694-","T49712-","G61626-","A61627-","G61628-","C61629-","T61630-","T61631-","A61674-","A61675-","T61676-","C61677-","G61678-","G61679-","A61680-","G61681-","A61682-","A61683-","T61684-","G61685-","T61686-","T61687-","T61688-","C61689-","C61690-","C61691-","A61692-","T61693-","T61694-","T61695-","T61696-","T61697-","A61698-","G61699-","G61700-","A61701-","T61702-","T61703-","A61704-","A61705-","C61706-","A61707-","T61708-","A61709-","G61710-","T61740-","A61741-","G61742-","T61743-","T61744-","A61764-","T61765-","T61766-","T61767-","G61768-","A61769-","T61770-","A61771-","A61791-","A61792-","T61793-","A61799-","A61800-","T61801-","C61802-","C61803-","G61804-","G61805-","A61806-","T61807-","G61808-","T61809-","T61810-","G61811-","T61812-","G61813-","T61814-","A62296-","A62297-","A62298-","T62299-","T62300-","A62301-","G62302-","T62358-","T62359-","T62360-","C62361-","T62362-","T62363-","A62364-","C62365-","A62366-","T62367-","A62368-","T62369-","T62370-","T62371-","T62372-","G88521-","A88522-","T88523-","C88524-","T88525-","C88526-","T88527-","A88528-","T88529-","A88530-","A88531-","T88532-","A88533-","T88534-","C88535-","T88536-","A88537-","G88538-","T88539-","T88540-","T88541-","C88542-","T88543-","T88544-","G88545-","C88546-","G88547-","T88548-","T88549-","T88550-","C88551-","A88552-","C88553-","A88554-","A88555-","A88556-","C88557-","A88558-","C88559-","A88560-","G88561-","G88562-","C88563-","T88564-","C88565-","G88566-","T88567-","C88568-","T88569-","C88570-","T88571-","C88572-","G88573-","C88574-","G88575-","A88576-","T88577-","G88578-","A88579-","G88580-","A88581-","T88582-","C88583-","T88584-","G88585-","T88586-","A88587-","T88588-","A88589-","G88590-","T88591-","A88592-","A88593-","C88594-","T88595-","A88596-","T88597-","G88598-","T88599-","A88600-","A88601-","A88602-","T88603-","G88604-","A88605-","T88606-","A88607-","A88608-","C88609-","T88610-","A88611-","G88612-","A88613-","T88614-","A88615-","G88616-","A88617-","A88618-","A88619-","G88620-","A88621-","T88622-","G88623-","T88624-","A88625-","G88626-","C88627-","T88628-","A88629-","T88630-","A88631-","T88632-","A88633-","G88634-","A88635-","T88636-","G88637-","A88638-","C88639-","G88640-","A88641-","T88642-","C88643-","C88644-","T88645-","T88646-","T88647-","A88648-","A88649-","G88650-","A88651-","G88652-","A88653-","G88654-","G88655-","T88656-","A88657-","T88658-","A88659-","A88660-","T88661-","A88662-","A88663-","C88664-","T88665-","T88666-","T88667-","A88668-","C88669-","C88670-","C88671-","C88672-","A88673-","A88674-","T88675-","C88676-","A88677-","G88678-","A88679-","T88680-","A88681-","G88682-","A88683-","C88684-","T88685-","G88686-","T88687-","T88688-","G88689-","T88690-","T88691-","A88692-","T88693-","G88694-","G88695-","T88696-","C88697-","T88698-","T88699-","C88700-","G88701-","G88702-","A88703-","A88704-","A88705-","A88706-","A88707-","G88708-","A88709-","A88710-","T88711-","T88712-","T88713-","T88714-","T88715-","A88716-","T88717-","A88718-","A88719-","A88720-","T88721-","T88722-","T88723-","T88724-","T88725-","C88726-","C88727-","A88728-","G88729-","T88730-","A88731-","T88732-","T88733-","T88734-","T88735-","C88736-","T88737-","A88738-","A88739-","A88740-","T88741-","A88742-","T88743-","A88744-","C88745-","G88746-","T88747-","A88748-","C88749-","T88750-","T88751-","G88752-","A88753-","T88754-","A88755-","T88756-","C88757-","T88758-","A88759-","A88760-","G88761-","A88762-","A88763-","A88764-","T88765-","C88766-","C88767-","T88768-","T88769-","A88770-","A88771-","T88772-","A88773-","A88774-","T88775-","A88776-","A88777-","T88778-","A88779-","G88780-","G88781-","A88782-","A88783-","T88784-","G88785-","G88786-","A88787-","T88788-","A88789-","A88790-","T88791-","C88792-","C88793-","G88794-","T88795-","C88796-","T88797-","A88798-","T88799-","T88800-","T88801-","T88802-","A88803-","T88804-","A88805-","A88806-","A88807-","G88808-","A88809-","A88810-","A88811-","T88812-","A88813-","C88814-","A88815-","T88816-","A88817-","T88818-","C88819-","G88820-","C88821-","A88822-","T88823-","A88824-","T88825-","T88826-","A88827-","T88828-","A88829-","C88830-","T88831-","T88832-","T88833-","T88834-","T88835-","T88836-","T88837-","T88838-","G88839-","G88840-","A88841-","A88842-","A88843-","T88844-","T88845-","G88846-","G88847-","A88848-","A88849-","T88850-","A88851-","C88852-","C88853-","G88854-","A88855-","T88856-","G88857-","T88858-","G88859-","T88860-","C88861-","T88862-","A88863-","C88864-","A88865-","T88866-","A88867-","A88868-","A88869-","T88870-","A88871-","C88872-","G88873-","C88874-","A88875-","A88876-","A88877-","G88878-","T88879-","C88880-","T88881-","A88882-","A88883-","A88884-","T88885-","A88886-","T88887-","T88888-","T88889-","T88890-","T88891-","T88892-","A88893-","G88894-","A88895-","G88896-","A88897-","A88898-","T88899-","C88900-","T88901-","T88902-","A88903-","G88904-","T88905-","T88906-","G88907-","G88908-","T88909-","C88910-","C88911-","A88912-","A88913-","A88914-","T88915-","T88916-","C88917-","T88918-","T88919-","T88920-","T88921-","C88922-","C88923-","A88924-","A88925-","G88926-","T88927-","A88928-","C88929-","G88930-","G88931-","T88932-","A88933-","A88934-","T88935-","A88936-","G88937-","A88938-","T88939-","T88940-","T88941-","T88942-","T88943-","C88944-","A88945-","T88946-","A88947-","T88948-","T88949-","G88950-","A88951-","A88952-","C88953-","G88954-","G88955-","T88956-","A88957-","T88958-","C88959-","T88960-","T88961-","C88962-","T88963-","T88964-","G88965-","A88966-","T88967-","C88968-","T88969-","C88970-","T88971-","G88972-","G88973-","T88974-","T88975-","C88976-","T88977-","A88978-","A88979-","T88980-","T88981-","C88982-","C88983-","G88984-","C88985-","A88986-","T88987-","T88988-","A88989-","A88990-","A88991-","T88992-","G88993-","A88994-","T88995-","G88996-","A88997-","A88998-","A88999-","C89000-","T89001-","A89002-","A89003-","G89004-","T89005-","C89006-","A89007-","C89008-","T89009-","A89010-","T89011-","T89012-","T89013-","T89014-","T89015-","A89016-","T89017-","A89018-","A89019-","C89020-","T89021-","A89022-","A89023-","C89024-","G89025-","A89026-","T89027-","T89028-","A89029-","C89030-","A89031-","T89032-","C89033-","A89034-","C89035-","C89036-","T89037-","C89038-","T89039-","A89040-","A89041-","C89042-","A89043-","T89044-","C89045-","A89046-","T89047-","C89048-","A89049-","T89050-","T89051-","T89052-","A89053-","C89054-","C89055-","A89056-","G89057-","G89058-","A89059-","T89060-","A89061-","C89062-","T89063-","G89064-","A89065-","T89066-","C89067-","T89068-","T89069-","C89070-","T89071-","T89072-","T89073-","T89074-","G89075-","T89076-","C89077-","G89078-","T89079-","A89080-","A89081-","A89082-","T89083-","A89084-","C89085-","A89086-","T89087-","G89088-","T89089-","C89090-","T89091-","A89092-","A89093-","T89094-","G89095-","T89096-","G89097-","T89098-","T89099-","A89100-","A89101-","A89102-","A89106-","A89107-","G89108-","A89109-","T89110-","C89111-","A89112-","T89113-","A89114-","C89115-","A89116-","A89117-","G89118-","T89119-","T89120-","A89121-","T89122-","A89123-","C89124-","G89125-","T89126-","C89127-","A89128-","T89129-","T89130-","T89131-","C89132-","A89133-","T89134-","C89135-","T89136-","G89137-","T89138-","A89139-","G89140-","T89141-","A89142-","T89143-","T89144-","C89145-","T89146-","T89147-","T89152-","T89153-","G89154-","A89155-","A89156-","G89157-","G89158-","A89159-","T89160-","A89161-","A89162-","A89163-","C89164-","T89165-","G89167-","T89168-","A89169-","C89170-","T89171-","A89172-","A89173-","T89174-","C89175-","T89176-","C89177-","T89178-","T89179-","C89180-","T89181-","T89182-","T89183-","A89184-","A89185-","C89186-","A89187-","G89188-","T89189-","C89190-","T89191-","G89192-","T89193-","T89194-","C89195-","A89196-","A89197-","A89198-","T89199-","T89200-","T89201-","A89202-","T89203-","A89204-","T89205-","C89206-","C89207-","T89208-","A89209-","T89210-","A89211-","T89212-","A89213-","T89214-","G89215-","A89216-","A89217-","A89218-","A89219-","A89220-","A89221-","T89222-","A89223-","G89224-","C89225-","A89226-","A89227-","C89228-","T89236-","G89237-","A89238-","T89239-","C89240-","A89241-","T89242-","C89243-","C89244-","G89245-","C89246-","G89247-","T89248-","C89249-","A89250-","A89251-","T89252-","A89253-","T89254-","T89255-","C89256-","T89257-","G89258-","T89259-","T89260-","C89261-","T89262-","A89263-","T89264-","C89265-","G89266-","T89267-","A89268-","G89269-","T89270-","G89271-","T89272-","A89273-","T89274-","A89275-","A89276-","C89277-","A89278-","A89279-","T89280-","C89281-","T89282-","T89283-","A89284-","T89285-","A89286-","T89287-","C89288-","T89289-","T89290-","C89291-","T89292-","T89293-","C89294-","T89295-","G89296-","T89297-","G89298-","A89299-","T89300-","A89301-","G89302-","T89303-","C89304-","G89305-","A89306-","T89307-","A89308-","C89309-","G89310-","T89311-","T89312-","A89313-","T89314-","A89315-","A89316-","A89317-","G89318-","G89319-","T89320-","T89321-","G89322-","A89323-","T89324-","A89325-","A89326-","C89327-","G89328-","A89329-","A89330-","A89331-","A89332-","T89333-","A89334-","T89335-","T89336-","T89337-","T89338-","T89339-","A89340-","T89341-","T89342-","T89343-","C89344-","G89345-","T89346-","G89347-","A89348-","A89349-","A89350-","T89351-","A89352-","A89353-","A89354-","G89355-","T89356-","C89357-","A89358-","T89359-","T89360-","G89361-","T89362-","A89363-","G89364-","G89365-","A89366-","T89367-","T89368-","T89369-","T89370-","G89371-","G89372-","T89395-","A89396-","T89397-","G89398-","A89399-","T89400-","T89401-","T89402-","T89403-","A89404-","T89405-","T89406-","T89407-","T89408-","T89409-","G89410-","G89411-","A89412-","A89413-","T89414-","G89415-","A89416-","T89417-","C89418-","T89419-","C89420-","A89421-","A89422-","T89423-","T89424-","A89425-","A89426-","A89427-","A89428-","T89429-","A89430-","G89431-","T89432-","C89433-","T89434-","C89435-","T89436-","T89437-","T89438-","A89439-","G89440-","A89441-","G89442-","T89443-","C89444-","C89445-","A89446-","T89447-","T89448-","T89449-","A89450-","A89451-","A89452-","G89453-","T89454-","T89455-","A89456-","C89457-","A89458-","A89459-","A89460-","C89461-","A89462-","A89463-","C89464-","T89465-","A89466-","G89467-","G89468-","A89469-","A89470-","A89471-","T89472-","T89473-","G89474-","G89475-","T89476-","T89477-","T89478-","A89479-","T89480-","G89481-","A89482-","T89483-","G89484-","T89485-","A89486-","T89487-","A89488-","A89489-","T89490-","T89491-","T89492-","T89493-","T89494-","T89495-","T89496-","A89497-","G89498-","T89499-","T89500-","T89501-","T89502-","T89503-","A89504-","T89505-","A89506-","G89507-","A89508-","T89509-","T89510-","C89511-","T89512-","T89513-","T89514-","A89515-","T89516-","T89517-","C89518-","T89519-","A89520-","T89521-","A89522-","C89523-","T89524-","T89525-","A89526-","A89527-","A89528-","A89529-","A89530-","A89531-","T89532-","G89533-","A89534-","A89535-","A89536-","A89537-","T89538-","A89539-","A89540-","A89541-","T89542-","A89543-","C89544-","A89545-","A89546-","A89547-","G89548-","G89549-","T89550-","T89551-","C89552-","T89553-","T89554-","G89555-","A89556-","G89557-","G89558-","G89559-","T89560-","T89561-","G89562-","T89563-","G89564-","T89565-","T89566-","A89567-","A89568-","T89569-","T89570-","G89571-","A89572-","A89573-","A89574-","G89575-","C89576-","G89577-","A89578-","T89579-","A89580-","A89581-","A89582-","T89583-","A89584-","A89585-","T89586-","C89587-","A89588-","T89589-","A89590-","A89591-","A89592-","T89593-","T89594-","A89595-","T89596-","T89597-","T89598-","C89599-","A89600-","T89601-","T89602-","A89603-","T89604-","C89605-","G89606-","C89607-","G89608-","A89609-","T89610-","A89611-","T89612-","C89613-","C89614-","G89615-","T89616-","T89617-","A89618-","A89619-","G89620-","T89621-","T89622-","T89623-","G89624-","T89625-","A89626-","T89627-","C89628-","G89629-","T89630-","A89631-","A89632-","T89633-","G89634-","G89635-","C89636-","G89637-","T89638-","G89639-","G89640-","T89641-","C89642-","A89643-","A89644-","T89645-","T89646-","A89647-","C89648-","G89649-","A89650-","A89651-","T89652-","A89653-","A89654-","A89655-","G89656-","C89657-","G89658-","G89659-","A89660-","T89661-","A89662-","C89663-","T89664-","A89665-","G89666-","T89667-","A89668-","G89669-","T89670-","T89671-","T89672-","C89673-","A89674-","C89675-","A89676-","A89677-","A89678-","G89679-","A89680-","T89681-","G89682-","G89683-","C89684-","T89685-","G89686-","A89687-","A89688-","A89689-","T89690-","C89691-","A89692-","G89693-","A89694-","G89695-","C89696-","T89697-","C89698-","A89699-","C89701-","T89702-","A89703-","A89704-","G89705-","A89706-","A89707-","A89708-","T89709-","A89710-","G89711-","C89712-","G89713-","C89714-","T89715-","G89716-","A89717-","A89718-","A89719-","A89720-","T89721-","A89722-","A89723-","A89724-","G89725-","A89726-","T89727-","A89728-","A89729-","A89730-","A89731-","A89732-","C89733-","G89734-","A89735-","G89736-","G89737-","A89738-","T89739-","A89740-","T89741-","T89742-","T89743-","T89744-","C89745-","C89746-","C89747-","G89748-","G89749-","A89750-","A89751-","G89752-","A89753-","T89754-","G89755-","T89756-","A89757-","A89758-","T89759-","A89760-","A89761-","T89762-","T89763-","C89764-","C89765-","A89766-","T89767-","C89768-","T89769-","A89770-","C89771-","T89772-","A89773-","A89774-","G89775-","C89776-","C89777-","C89778-","A89779-","A89780-","A89781-","A89782-","C89783-","C89784-","A89785-","A89786-","A89787-","C89788-","G89789-","A89790-","A89791-","C89792-","C89793-","A89794-","C89795-","T89796-","A89797-","C89798-","T89799-","C89800-","C89801-","T89802-","C89803-","G89804-","T89805-","A89806-","A89807-","A89808-","C89809-","C89810-","A89811-","G89812-","C89813-","G89814-","G89815-","C89816-","T89817-","A89818-","C89819-","T89820-","A89821-","A89822-","A89823-","A89824-","G89825-","A89826-","T89827-","C89828-","A89829-","A89830-","C89831-","C89832-","A89833-","A89834-","A89835-","A89836-","A89837-","G89838-","G89839-","A89840-","T89841-","A89842-","A89843-","A89844-","G89845-","A89846-","A89847-","A89848-","A89849-","G89850-","G89851-","A89852-","G89853-","G89854-","A89855-","A89856-","G89857-","T89858-","G89859-","G89860-","A89861-","A89862-","G89863-","A89864-","A89865-","G89866-","T89867-","A89868-","G89869-","T89870-","T89871-","A89872-","T89873-","A89874-","G89875-","A89876-","G89877-","G89878-","A89879-","A89880-","T89881-","A89882-","T89883-","C89884-","A89885-","T89886-","C89887-","A89888-","A89889-","A89890-","C89891-","A89892-","A89893-","C89894-","T89895-","G89896-","A89897-","A89898-","G89899-","A89900-","A89901-","A89902-","A89903-","T89904-","T89905-","C89906-","T89907-","C89908-","C89909-","A89910-","C89911-","C89912-","T89913-","C89914-","C89915-","G89916-","T89917-","C89918-","A89919-","T89920-","C89921-","A89922-","T89923-","C89924-","T89925-","C89926-","C89927-","T89928-","G89929-","G89930-","A89931-","G89932-","T89933-","C89934-","G89935-","G89936-","C89937-","G89938-","A89939-","C89940-","A89941-","T89942-","T89943-","G89944-","T89945-","A89946-","G89947-","A89948-","A89949-","A89950-","G89951-","C89952-","G89953-","T89954-","G89955-","G89956-","C89957-","C89958-","G89959-","C89960-","T89961-","G89962-","T89963-","A89964-","G89965-","A89966-","G89967-","C89968-","T89969-","C89970-","G89971-","A89972-","T89973-","G89974-","A89975-","T89976-","A89977-","G89978-","C89979-","G89980-","A89981-","C89982-","G89983-","G89984-","G89985-","G89986-","A89987-","T89988-","G89989-","A89990-","T89991-","G89992-","A89993-","A89994-","C89995-","C89996-","T89997-","A89998-","T89999-","G90000-","G90001-","T90002-","A90003-","C90004-","A90005-","A90006-","G90007-","T90008-","T90009-","G90010-","A90011-","A90012-","G90013-","C90014-","T90015-","G90016-","G90017-","T90018-","A90019-","A90020-","A90021-","G90022-","T90023-","A90024-","A90025-","A90026-","T90027-","C90028-","A90029-","T90030-","A90031-","G90032-","T90033-","G90034-","C90035-","T90036-","A90037-","G90038-","A90039-","A90040-","G90041-","C90042-","G90043-","A90044-","T90045-","C90046-","T90047-","C90048-","T90049-","C90050-","T90051-","G90052-","A90053-","C90054-","C90055-","T90056-","A90057-","A90058-","A90059-","G90060-","G90061-","T90062-","G90063-","G90064-","C90065-","T90066-","A90067-","C90068-","C90069-","G90070-","A90071-","C90072-","A90073-","A90074-","T90075-","A90076-","T90077-","C90078-","G90079-","T90080-","T90081-","A90082-","A90083-","A90084-","G90085-","A90086-","T90087-","C90088-","T90089-","T90090-","A90091-","A90092-","G90093-","A90094-","A90095-","A90096-","A90097-","T90098-","T90099-","A90100-","T90101-","T90102-","A90103-","C90104-","T90105-","A90106-","G90107-","A90108-","A90109-","T90110-","C90111-","T90112-","C90113-","T90114-","G90115-","C90116-","A90117-","G90118-","T90119-","A90120-","T90121-","C90122-","G90123-","A90124-","C90125-","T90126-","G90127-","T90128-","T90129-","C90130-","T90131-","A90132-","G90133-","A90134-","G90135-","G90136-","A90137-","T90138-","G90139-","T90140-","T90141-","C90142-","A90143-","A90144-","G90145-","C90146-","A90147-","G90148-","C90149-","T90150-","G90151-","G90152-","T90153-","A90154-","T90155-","C90156-","T90157-","C90158-","T90159-","A90160-","G90161-","A90162-","C90163-","A90164-","A90165-","T90166-","T90167-","T90168-","A90169-","C90170-","T90171-","T90172-","C90173-","T90174-","A90175-","T90176-","G90177-","A90178-","C90179-","T90180-","A90181-","A90182-","A90183-","G90184-","C90185-","T90186-","A90187-","T90188-","T90189-","A90190-","C90191-","A90192-","A90193-","C90194-","A90195-","C90196-","T90197-","A90198-","T90199-","C90200-","T90201-","G90202-","A90203-","T90204-","C90205-","T90206-","A90207-","G90208-","T90209-","C90210-","A90211-","C90212-","C90213-","G90214-","A90215-","G90216-","G90217-","G90218-","A90219-","A90220-","A90221-","A90222-","T90223-","C90224-","T90225-","A90226-","A90227-","A90228-","G90229-","T90230-","T90231-","G90232-","T90233-","T90234-","C90235-","G90236-","T90237-","A90238-","A90239-","A90240-","A90241-","A90242-","A90243-","G90244-","T90245-","T90246-","A90247-","A90248-","A90249-","A90250-","C90251-","T90252-","T90253-","G90254-","T90255-","A90256-","A90257-","G90258-","A90259-","A90260-","G90261-","T90262-","A90263-","A90264-","A90265-","T90266-","G90267-","C90268-","G90269-","T90270-","G90271-","C90272-","A90273-","C90274-","T90275-","T90276-","T90277-","T90278-","T90279-","T90280-","A90281-","T90282-","A90283-","A90284-","A90285-","G90286-","A90287-","T90288-","G90289-","G90290-","T90291-","A90292-","A90293-","A90294-","C90295-","T90296-","G90297-","T90298-","T90299-","T90300-","A90301-","C90302-","C90303-","G90304-","A90305-","T90306-","A90307-","A90308-","T90309-","A90310-","A90311-","T90312-","T90313-","T90314-","T90315-","T90316-","T90317-","A90318-","A90319-","A90320-","T90321-","C90322-","C90323-","T90324-","G90325-","T90326-","A90327-","T90328-","C90329-","A90330-","G90331-","A90332-","C90333-","G90334-","A90335-","T90336-","A90337-","A90338-","T90339-","C90340-","C90341-","A90342-","G90343-","C90344-","G90345-","T90346-","A90347-","T90348-","G90349-","A90350-","G90351-","G90352-","T90353-","T90354-","T90355-","T90356-","G90357-","C90358-","A90359-","A90360-","C90361-","A90362-","T90363-","G90364-","T90365-","T90366-","A90367-","A90368-","A90369-","A90370-","T90371-","T90372-","C90373-","C90374-","T90375-","A90376-","C90377-","T90378-","C90379-","A90380-","T90381-","T90382-","T90383-","A90384-","A90385-","C90386-","A90387-","G90388-","A90389-","T90390-","G90391-","T90392-","A90393-","G90394-","T90395-","A90396-","G90397-","T90398-","A90399-","T90400-","A90401-","T90402-","G90403-","A90404-","A90405-","C90406-","A90407-","A90408-","A90409-","C90410-","G90411-","T90412-","G90413-","G90414-","G90415-","A90416-","A90417-","G90418-","A90419-","G90420-","G90421-","C90422-","A90423-","T90424-","T90425-","A90426-","A90427-","C90428-","T90429-","A90430-","G90431-","A90432-","T90433-","T90434-","A90435-","A90436-","T90437-","T90438-","T90439-","T90440-","T90441-","G90442-","T90443-","G90444-","G90445-","G90446-","A90447-","A90448-","G90449-","T90450-","G90451-","A90452-","T90453-","T90454-","C90455-","A90456-","A90457-","A90458-","A90459-","G90460-","G90461-","A90462-","C90463-","G90464-","T90465-","A90466-","G90467-","A90468-","C90469-","A90470-","A90471-","T90472-","A90473-","C90474-","T90475-","T90476-","T90477-","T90478-","A90479-","C90480-","G90481-","G90482-","A90483-","A90484-","A90485-","A90486-","A90487-","T90488-","G90489-","C90490-","A90491-","T90492-","A90493-","T90494-","A90495-","C90496-","A90497-","G90498-","A90499-","A90500-","T90501-","C90502-","G90503-","C90504-","A90505-","A90506-","T90507-","G90508-","C90509-","T90510-","A90511-","A90512-","A90513-","A90514-","G90515-","A90516-","G90517-","A90518-","T90519-","C90520-","G90521-","T90522-","A90523-","T90524-","T90525-","T90526-","T90527-","T90528-","G90529-","T90530-","T90531-","A90532-","G90533-","A90534-","G90535-","T90536-","A90537-","T90538-","A90539-","T90540-","A90541-","A90542-","C90543-","G90544-","T90545-","T90546-","A90547-","T90548-","G90549-","A90550-","A90551-","A90552-","C90553-","G90554-","A90555-","A90556-","T90557-","T90558-","A90559-","A90560-","T90561-","T90562-","G90563-","T90564-","T90565-","T90566-","T90567-","A90568-","T90569-","A90570-","A90571-","A90572-","C90573-","A90574-","A90575-","A90576-","A90577-","A90578-","T90579-","A90580-","T90581-","A90582-","A90583-","A90584-","G90585-","A90586-","A90587-","A90588-","T90589-","C90590-","G90591-","T172130-","T172131-","C172132-","C172133-","T173843-","A173844-","G173845-","T173846-","A173847-"],"OPG080":["S84-","N85-"]},"labels":{"aa":"OPG080: S84-, N85-"}}}]}]}]}]},{"name":"NODE_0000159","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C132698T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}},"children":[{"name":"OP555508","node_attrs":{"div":4,"accession":"OP555508","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555508/2022-07-26"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-26"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0416/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T607-","G40375A","C92352T","C120425T"],"OPG137":["S275L"]},"labels":{"aa":"OPG137: S275L"}}},{"name":"OP555535","node_attrs":{"div":6,"accession":"OP555535","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555535/2022-08-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-03"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0454/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T594A","-608T","-609T","G52732A","C55917T","C115705T","G132625A","C167955T","-196615A","-196616T"]}}},{"name":"OP555512","node_attrs":{"div":1,"accession":"OP555512","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555512/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0424/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000160","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C18441T","G22415A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG031":["E130K"]},"labels":{"aa":"OPG031: E130K"}},"children":[{"name":"OP442545","node_attrs":{"div":5,"accession":"OP442545","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"strain_display":{"value":"USA/OP442545/2022-08-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-08-19"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00069/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C129070T","G180963A"],"OPG209":["R149Q"]},"labels":{"aa":"OPG209: R149Q"}}},{"name":"OP442548","node_attrs":{"div":3,"accession":"OP442548","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"strain_display":{"value":"USA/OP442548/2022-08-18"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-08-18"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00072/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000161","node_attrs":{"div":7,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G70002A","G143951A","C148604T","G154188A"],"OPG089":["R46K"],"OPG165":["D146N"],"OPG174":["M264I"]},"labels":{"aa":"OPG089: R46K; OPG165: D146N; OPG174: M264I"}},"children":[{"name":"OR643700","node_attrs":{"div":10,"accession":"OR643700","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR643700/2023-08-24"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-08-24"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00558/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C96773T","A166129G","G168741A"],"OPG117":["S242L"],"OPG195":["R171K"]},"labels":{"aa":"OPG117: S242L; OPG195: R171K"}}},{"name":"OR499993","node_attrs":{"div":7,"accession":"OR499993","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499993/2023-07-06"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-07-06"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00537/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000162","node_attrs":{"div":9,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G70425A","C137966T"],"OPG089":["G187E"],"OPG154":["E29K"]},"labels":{"aa":"OPG089: G187E; OPG154: E29K"}},"children":[{"name":"OR643711","node_attrs":{"div":9,"accession":"OR643711","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR643711/2023-08-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-08-02"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00555/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR643708","node_attrs":{"div":9,"accession":"OR643708","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR643708/2023-07-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-07-28"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00553/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000163","node_attrs":{"div":8,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C14823A"],"OPG025":["D149Y"]},"labels":{"aa":"OPG025: D149Y"}},"children":[{"name":"OR643702","node_attrs":{"div":8,"accession":"OR643702","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR643702/2023-08-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-08-08"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00560/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR643701","node_attrs":{"div":8,"accession":"OR643701","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR643701/2023-08-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-08-07"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00559/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000164","node_attrs":{"div":1,"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G5595A","C191615T"],"OPG015":["Q188*"],"OPG015_dup":["Q188*"]},"labels":{"aa":"OPG015: Q188*; OPG015_dup: Q188*","clade":"B.1.8"}},"children":[{"name":"OP215224","node_attrs":{"div":1,"accession":"OP215224","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP215224/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.8"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI235"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000165","node_attrs":{"div":2,"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G161296A","-179188T","-179189A"]}},"children":[{"name":"OP331337","node_attrs":{"div":2,"accession":"OP331337","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP331337/2022-06-29"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-29"},"lineage":{"value":"B.1.8"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000183"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G902A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C196308T"],"OPG001":["S225L"],"OPG001_dup":["S225L"]},"labels":{"aa":"OPG001: S225L; OPG001_dup: S225L"}}},{"name":"OP626129","node_attrs":{"div":3,"accession":"OP626129","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP626129/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.8"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI491"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C24929T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179188-","A179189-"],"OPG040":["D184N"]},"labels":{"aa":"OPG040: D184N"}}},{"name":"NODE_0000166","node_attrs":{"div":5,"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G89716A","G128858A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","C186220T"],"OPG110":["E29K"],"OPG210":["A1622V"]},"labels":{"aa":"OPG110: E29K; OPG210: A1622V"}},"children":[{"name":"OP615338","node_attrs":{"div":5,"accession":"OP615338","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP615338/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.8"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI459"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OP863250","node_attrs":{"div":5,"accession":"OP863250","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP863250/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.8"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI600"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G181052-"],"OPG209":["G179-"]},"labels":{"aa":"OPG209: G179-"}}}]}]},{"name":"NODE_0000167","node_attrs":{"div":3,"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G78034A","C80111T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG099":["D124N"]},"labels":{"aa":"OPG099: D124N"}},"children":[{"name":"ON720849","node_attrs":{"div":4,"accession":"ON720849","author":{"author":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"strain_display":{"value":"Spain/ON720849/2022-05-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"Microbial Genomics, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"},"date":{"value":"2022-05-27"},"lineage":{"value":"B.1.8"},"country":{"value":"Spain"},"strain":{"value":"MpxV/Spain/MD-HGUGM-6532064/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A327-","T604-","T605-","T606-","A1697-","A8055-","A9529-","C11749-","T15127-","T16099-","A19360-","A21081-","A27114-","A28529-","A28530-","A28602-","T32194-","A33199-","T34046-","T35571-","T37982-","T39131-","T39866-","T41744-","A43500-","T43509-","T46648-","A55124-","T56040-","A57277-","A58650-","A62041-","T64752-","A64935-","G69145-","A69744-","T76084-","T76085-","A76890-","A79181-","T79229-","A79460-","A79787-","T80849-","T88095-","T88836-","A89106-","A91705-","T94647-","T94795-","A98080-","T103367-","T105360-","T108715-","A110978-","T114518-","T114755-","A116014-","T116963-","T121121-","C122649T","A123995-","A124727-","A127250-","A127754-","A128933-","A132023-","A132024-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133639-","T137886-","A138474-","A142466-","A144230-","A148000-","A148351-","T150539-","A150635-","A151986-","A152676-","T152686-","A153424-","A154129-","T155424-","A157997-","T163597-","T168120-","A168962-","A170728-","T170904-","T172087-","T172667-","T178048-","A179950-","G181052-","A181253-","A182646-","T187080-","A190935-","T195519-","A196593-","A196611-","A196612-","A196613-","A196614-","T197183-"],"OPG016":["T176-"],"OPG044":["K147-"],"OPG084":["F11-"],"OPG087":["G97-"],"OPG102":["K33-","K126-","K235-"],"OPG115":["S46-"],"OPG117":["K678-"],"OPG134":["N89-"],"OPG143":["D223N"],"OPG145":["M17-"],"OPG149":["K19-"],"OPG151":["N4-","K1034-"],"OPG163":["N89-"],"OPG165":["M239-"],"OPG172":["I192-"],"OPG178":["M160-"],"OPG180":["N245-"],"OPG189":["F89-"],"OPG193":["F263-"],"OPG198":["K231-"],"OPG208":["N229-"],"OPG209":["G179-"],"OPG210":["K431-"]},"labels":{"aa":"OPG016: T176-; OPG044: K147-; OPG084: F11-; OPG087: G97-; OPG102: K33-, K126-, K235-; OPG115: S46-; OPG117: K678-; OPG134: N89-; OPG143: D223N; OPG145: M17-; OPG149: K19-; OPG151: N4-, K1034-; OPG163: N89-; OPG165: M239-; OPG172: I192-; OPG178: M160-; OPG180: N245-; OPG189: F89-; OPG193: F263-; OPG198: K231-; OPG208: N229-; OPG209: G179-; OPG210: K431-"}}},{"name":"ON622718","node_attrs":{"div":4,"accession":"ON622718","author":{"author":"Martinez-Puchol,S.,Coello,A.,Bordoy,A.E.,Soler,L.,Panisello,D.,Gonzalez-Gomez,S.,Clara,G.,Paris de Leon,A.,Not,A.,Hernandez,A.,Bofill-Mas,S.,Saludes,V.,Blanco,I.,Martro,E.,Cardona,P.-J.","value":"Martinez-Puchol,S.,Coello,A.,Bordoy,A.E.,Soler,L.,Panisello,D.,Gonzalez-Gomez,S.,Clara,G.,Paris de Leon,A.,Not,A.,Hernandez,A.,Bofill-Mas,S.,Saludes,V.,Blanco,I.,Martro,E.,Cardona,P.-J."},"strain_display":{"value":"Spain/ON622718/2022-05-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"Microbiology, Hospital Universitari Germans Trias i Pujol, Spain"},"date":{"value":"2022-05-20"},"lineage":{"value":"B.1.8"},"country":{"value":"Spain"},"strain":{"value":"MPXV/ES0001/HUGTiP/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C14113-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T139150C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","-196615A","-196616A"],"OPG156":["Q87R"]},"labels":{"aa":"OPG156: Q87R"}}},{"name":"NODE_0000168","node_attrs":{"div":5,"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G22643A","G63811A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG038":["H173Y"]},"labels":{"aa":"OPG038: H173Y"}},"children":[{"name":"OP390176","node_attrs":{"div":5,"accession":"OP390176","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"strain_display":{"value":"Colombia/OP390176/2022-08-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"date":{"value":"2022-08-12"},"lineage":{"value":"B.1.8"},"country":{"value":"Colombia"},"strain":{"value":"ATL-UNIMOL-MPX-292895-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP477454","node_attrs":{"div":5,"accession":"OP477454","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OP477454/2022-08-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-08-23"},"lineage":{"value":"B.1.8"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-23267-O"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP459214","node_attrs":{"div":5,"accession":"OP459214","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OP459214/2022-08-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"date":{"value":"2022-08-30"},"lineage":{"value":"B.1.8"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-23631-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP628447","node_attrs":{"div":7,"accession":"OP628447","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OP628447/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.8"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-082515/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C112964T","G177995A","-180517A","-180518A","-180519T","-180520G","-180521A","-180522C","-180523G","-180524A","-180525T","-180526A","-180527T","-180528A","-180529C","-180530G","-180531G","-180532A","-180533T","-180534T"],"OPG132":["E193K"]},"labels":{"aa":"OPG132: E193K"}}},{"name":"OQ099607","node_attrs":{"div":6,"accession":"OQ099607","author":{"author":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y.","value":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y."},"strain_display":{"value":"USA/OQ099607/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.8"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_FL0010"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C804T","G104774A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-180517A","-180518A","-180519T","-180520G","-180521A","-180522C","-180523G","-180524A","-180525T","-180526A","-180527T","-180528A","-180529C","-180530G","-180531G","-180532A","-180533T","-180534T","G196406A"]}}}]}]}]},{"name":"NODE_0000169","node_attrs":{"div":2,"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","T11329-","A11330-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","A11340-","T11341-","A11342-","T11344-","T11345-","A11347-","T11349-","A11351-","A11352-","T11353-","A11355-","A11356-","T11357-","A11359-","A11360-","T11361-","A11363-","A11365-","A11367-","A11368-","T11369-","T11371-","A11372-","A11373-","T11374-","T11376-","A11377-","T11380-","T11381-","T11382-","A11383-","T11384-","A11386-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","A11396-","T11397-","T11398-","T11399-","T11400-","A11402-","A11405-","T11407-","T11408-","A11410-","A11411-","T11412-","T11414-","T11415-","T11416-","T11418-","A11419-","A11421-","T11422-","T11423-","T11426-","T11427-","A11429-","T11430-","A11434-","A11435-","T11436-","T11439-","T11440-","A11441-","T11442-","A11443-","A11445-","T11446-","T11448-","A11449-","T11450-","A11451-","T11452-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","A11463-","T11464-","T11466-","A11467-","A11468-","T11469-","T11471-","T11472-","A11474-","A11476-","T11477-","T11479-","A11481-","A11482-","A11487-","T11488-","T11489-","T11491-","A11492-","A11495-","T11497-","A11498-","A11499-","A11500-","A11502-","T11503-","A11504-","T11506-","A11507-","A11509-","A11511-","T11512-","T11513-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","T11526-","A11527-","A11528-","A11530-","T11534-","T11535-","T11537-","A11539-","A11540-","A11542-","A11543-","T11545-","T11547-","T11548-","T11549-","T11551-","T11554-","T11557-","T11558-","T11559-","T11561-","A11563-","A11564-","T11565-","A11567-","T11568-","T11570-","T11571-","A11572-","A11573-","T11574-","T11576-","T11578-","T11579-","T11580-","A11581-","A11582-","A11584-","T11585-","A11586-","A11587-","T11590-","A11591-","A11593-","A11595-","A11596-","A11597-","T11598-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","T11607-","A11608-","T11610-","A11611-","A11612-","A11614-","A11615-","T11616-","T11617-","A11622-","A11623-","A11624-","A11626-","T11627-","A11628-","A11629-","A11631-","A11633-","T11634-","T11636-","A11638-","A11640-","A11641-","A11642-","A11644-","T11648-","T11649-","T11650-","T11651-","T11652-","T11654-","A11655-","T11656-","T11658-","A11659-","T11660-","A11661-","A11662-","T11664-","T11666-","A11667-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","A11679-","T11680-","A11683-","T11684-","A11685-","T11687-","T11688-","A11691-","T11692-","T11693-","A11695-","A11697-","T11698-","A11699-","T11702-","T11704-","A11707-","A11708-","T11709-","A11714-","T11715-","T11717-","T11719-","A11722-","T11723-","A11725-","T11726-","A11729-","A11731-","T11732-","A11734-","T11735-","T11736-","A11738-","A11743-","T11744-","T11746-","T11752-","T11753-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","T11764-","A11765-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","A11774-","T11775-","T11778-","T11780-","A11781-","A11782-","A11784-","A11785-","T11786-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","T11802-","A11803-","A11804-","A11805-","T11807-","A11808-","T11809-","T11811-","T11813-","T11815-","A11816-","T11817-","A11818-","T11822-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","A11834-","A11836-","T11839-","A11842-","T11843-","A11844-","T11845-","T11846-","A11849-","A11850-","A11852-","T11853-","A11856-","T11857-","T11858-","A11861-","T11863-","A11864-","A11866-","A11870-","T11871-","A11872-","T11873-","A11876-","T11877-","A11878-","T11879-","A11885-","A11886-","T11887-","T11889-","A11891-","T11892-","A11893-","T11894-","A11895-","T11897-","A11899-","A11900-","T11901-","T11902-","A11903-","T11905-","A11906-","T11907-","A11908-","T11909-","T11911-","T11912-","A11915-","A11918-","A11920-","T11921-","A11925-","T11927-","T11928-","A11930-","T11931-","T11932-","T11934-","T11935-","T11936-","T11937-","A11939-","A11940-","T11941-","A11942-","T11943-","A11945-","A11946-","A11947-","A11949-","A11951-","T11952-","T11955-","T11956-","T11957-","T11960-","T11961-","A11962-","T11963-","A11965-","T11966-","T11967-","T11968-","T11970-","A11973-","T11974-","A11975-","T11977-","T11980-","A11981-","A11983-","A11984-","T11985-","A11986-","T11988-","A11989-","A11991-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","T12002-","A12003-","T12008-","T12009-","T12010-","A12013-","T12014-","T12015-","T12017-","A12020-","A12021-","A12022-","A12023-","A12024-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","A12035-","A12036-","A12037-","T12038-","T12040-","A12041-","A12042-","A12043-","T12044-","T12046-","A12047-","A12049-","T12050-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","T12059-","A12060-","T12061-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","A12070-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","A12079-","T12080-","A12081-","A12082-","T12083-","A12085-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","T12097-","A12100-","T12102-","A12105-","A12106-","A12108-","T12109-","T12111-","T12112-","A12113-","A12115-","T12116-","T12119-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","A12129-","A12130-","T12131-","A12132-","A12133-","T12138-","T12140-","T12141-","A12142-","T12143-","T12145-","A12146-","T12147-","T12148-","T12151-","T12152-","T12153-","A12155-","T12156-","T12157-","A12158-","A12159-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","A12170-","T12171-","T12173-","T12175-","A12176-","T12177-","A12178-","T12179-","T12181-","A12182-","T12183-","A12184-","T12185-","A12187-","A12189-","T12190-","A12192-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","A12208-","A12209-","A12211-","T12214-","T12216-","A12217-","A12219-","A12220-","T12221-","A12222-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","T12232-","A12233-","T12234-","A12235-","A12237-","A12238-","G149818A","G151362A","A192499-","A192500-","T192502-","A192504-","T192505-","A192506-","A192507-","T192509-","T192510-","A192511-","T192513-","T192514-","A192515-","A192516-","T192518-","A192520-","T192521-","A192522-","A192523-","T192525-","T192526-","A192527-","T192529-","T192530-","A196614-"],"OPG176":["D4N"]},"labels":{"aa":"OPG176: D4N","clade":"B.1.15"}},"children":[{"name":"ON694335","node_attrs":{"div":2,"accession":"ON694335","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/ON694335/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.15"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI018"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C11328-","C11331-","G11332-","G11339-","C11343-","C11346-","C11348-","C11350-","G11354-","C11358-","C11362-","C11364-","C11366-","C11370-","G11375-","G11378-","G11379-","G11385-","C11387-","G11394-","C11395-","C11401-","G11403-","C11404-","G11406-","C11409-","G11413-","C11417-","G11420-","C11424-","G11425-","G11428-","G11431-","G11432-","C11433-","G11437-","G11438-","C11444-","G11447-","C11453-","C11454-","G11455-","G11462-","C11465-","G11470-","G11473-","C11475-","C11478-","G11480-","C11483-","C11484-","G11485-","G11486-","C11490-","G11493-","C11494-","G11496-","G11501-","C11505-","G11508-","G11510-","G11514-","C11525-","C11529-","G11531-","C11532-","C11533-","G11536-","G11538-","G11541-","G11544-","G11546-","C11550-","C11552-","C11553-","C11555-","G11556-","G11560-","C11562-","C11566-","G11569-","G11575-","C11577-","G11583-","G11588-","G11589-","G11592-","C11594-","G11599-","G11606-","C11609-","G11613-","G11618-","G11619-","G11620-","C11621-","C11625-","G11630-","C11632-","G11635-","C11637-","C11639-","G11643-","C11645-","C11646-","C11647-","G11653-","G11657-","G11663-","G11665-","G11668-","C11678-","C11681-","C11682-","G11686-","G11689-","G11690-","C11694-","C11696-","G11700-","G11701-","G11703-","C11705-","C11706-","C11710-","G11711-","G11712-","G11713-","C11716-","C11718-","C11720-","C11721-","C11724-","C11727-","G11728-","G11730-","G11733-","G11737-","C11739-","G11740-","G11741-","C11742-","C11745-","C11747-","C11748-","C11749-","C11750-","C11751-","C11754-","C11755-","G11763-","G11766-","C11773-","C11776-","G11777-","G11779-","G11783-","C11787-","C11801-","G11806-","C11810-","G11812-","G11814-","G11819-","C11820-","C11821-","C11823-","C11832-","C11833-","C11835-","G11837-","C11838-","C11840-","C11841-","C11847-","C11848-","C11851-","G11854-","C11855-","C11859-","C11860-","C11862-","G11865-","G11867-","G11868-","G11869-","C11874-","G11875-","C11880-","G11881-","C11882-","C11883-","G11884-","G11888-","C11890-","C11896-","C11898-","G11904-","G11910-","G11913-","G11914-","G11916-","G11917-","C11919-","C11922-","C11923-","G11924-","G11926-","C11929-","G11933-","C11938-","C11944-","G11948-","G11950-","G11953-","G11954-","C11958-","C11959-","C11964-","C11969-","C11971-","C11972-","G11976-","G11978-","G11979-","C11982-","C11987-","C11990-","C11992-","C11999-","C12000-","G12001-","C12004-","G12005-","G12006-","C12007-","C12011-","C12012-","C12016-","C12018-","C12019-","C12025-","C12033-","C12034-","C12039-","C12045-","C12048-","C12051-","G12058-","C12062-","C12069-","C12071-","G12078-","C12084-","G12086-","C12087-","C12088-","C12095-","C12096-","C12098-","G12099-","G12101-","G12103-","C12104-","C12107-","G12110-","G12114-","C12117-","G12118-","C12120-","G12128-","G12134-","C12135-","C12136-","G12137-","G12139-","C12144-","C12149-","C12150-","C12154-","C12160-","C12168-","G12169-","G12172-","C12174-","C12180-","G12186-","G12188-","G12191-","C12193-","G12207-","G12210-","G12212-","C12213-","G12215-","C12218-","G12223-","C12231-","G12236-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G192501-","C192503-","G192508-","G192512-","G192517-","C192519-","G192524-","G192528-"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-"}}},{"name":"NODE_0000170","node_attrs":{"div":6,"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C8385T","-11326A","-11327T","-11329T","-11330A","-11333A","-11334T","-11335A","-11336T","-11337T","-11338A","-11340A","-11341T","-11342A","-11344T","-11345T","-11347A","-11349T","-11351A","-11352A","-11353T","-11355A","-11356A","-11357T","-11359A","-11360A","-11361T","-11363A","-11365A","-11367A","-11368A","-11369T","-11371T","-11372A","-11373A","-11374T","-11376T","-11377A","-11380T","-11381T","-11382T","-11383A","-11384T","-11386A","-11388A","-11389T","-11390A","-11391A","-11392T","-11393A","-11396A","-11397T","-11398T","-11399T","-11400T","-11402A","-11405A","-11407T","-11408T","-11410A","-11411A","-11412T","-11414T","-11415T","-11416T","-11418T","-11419A","-11421A","-11422T","-11423T","-11426T","-11427T","-11429A","-11430T","-11434A","-11435A","-11436T","-11439T","-11440T","-11441A","-11442T","-11443A","-11445A","-11446T","-11448T","-11449A","-11450T","-11451A","-11452T","-11456T","-11457T","-11458A","-11459T","-11460T","-11461T","-11463A","-11464T","-11466T","-11467A","-11468A","-11469T","-11471T","-11472T","-11474A","-11476A","-11477T","-11479T","-11481A","-11482A","-11487A","-11488T","-11489T","-11491T","-11492A","-11495A","-11497T","-11498A","-11499A","-11500A","-11502A","-11503T","-11504A","-11506T","-11507A","-11509A","-11511A","-11512T","-11513T","-11515T","-11516T","-11517T","-11518A","-11519T","-11520T","-11521A","-11522T","-11523A","-11524T","-11526T","-11527A","-11528A","-11530A","-11534T","-11535T","-11537T","-11539A","-11540A","-11542A","-11543A","-11545T","-11547T","-11548T","-11549T","-11551T","-11554T","-11557T","-11558T","-11559T","-11561T","-11563A","-11564A","-11565T","-11567A","-11568T","-11570T","-11571T","-11572A","-11573A","-11574T","-11576T","-11578T","-11579T","-11580T","-11581A","-11582A","-11584A","-11585T","-11586A","-11587A","-11590T","-11591A","-11593A","-11595A","-11596A","-11597A","-11598T","-11600T","-11601T","-11602T","-11603A","-11604T","-11605A","-11607T","-11608A","-11610T","-11611A","-11612A","-11614A","-11615A","-11616T","-11617T","-11622A","-11623A","-11624A","-11626A","-11627T","-11628A","-11629A","-11631A","-11633A","-11634T","-11636T","-11638A","-11640A","-11641A","-11642A","-11644A","-11648T","-11649T","-11650T","-11651T","-11652T","-11654T","-11655A","-11656T","-11658T","-11659A","-11660T","-11661A","-11662A","-11664T","-11666T","-11667A","-11669A","-11670A","-11671A","-11672T","-11673T","-11674A","-11675T","-11676A","-11677A","-11679A","-11680T","-11683A","-11684T","-11685A","-11687T","-11688T","-11691A","-11692T","-11693T","-11695A","-11697A","-11698T","-11699A","-11702T","-11704T","-11707A","-11708A","-11709T","-11714A","-11715T","-11717T","-11719T","-11722A","-11723T","-11725A","-11726T","-11729A","-11731A","-11732T","-11734A","-11735T","-11736T","-11738A","-11743A","-11744T","-11746T","-11752T","-11753T","-11756T","-11757T","-11758T","-11759T","-11760T","-11761T","-11762A","-11764T","-11765A","-11767A","-11768T","-11769A","-11770T","-11771T","-11772T","-11774A","-11775T","-11778T","-11780T","-11781A","-11782A","-11784A","-11785A","-11786T","-11788A","-11789A","-11790T","-11791A","-11792T","-11793T","-11794A","-11795A","-11796T","-11797A","-11798T","-11799T","-11800T","-11802T","-11803A","-11804A","-11805A","-11807T","-11808A","-11809T","-11811T","-11813T","-11815T","-11816A","-11817T","-11818A","-11822T","-11824T","-11825T","-11826T","-11827A","-11828T","-11829T","-11830T","-11831A","-11834A","-11836A","-11839T","-11842A","-11843T","-11844A","-11845T","-11846T","-11849A","-11850A","-11852A","-11853T","-11856A","-11857T","-11858T","-11861A","-11863T","-11864A","-11866A","-11870A","-11871T","-11872A","-11873T","-11876A","-11877T","-11878A","-11879T","-11885A","-11886A","-11887T","-11889T","-11891A","-11892T","-11893A","-11894T","-11895A","-11897T","-11899A","-11900A","-11901T","-11902T","-11903A","-11905T","-11906A","-11907T","-11908A","-11909T","-11911T","-11912T","-11915A","-11918A","-11920A","-11921T","-11925A","-11927T","-11928T","-11930A","-11931T","-11932T","-11934T","-11935T","-11936T","-11937T","-11939A","-11940A","-11941T","-11942A","-11943T","-11945A","-11946A","-11947A","-11949A","-11951A","-11952T","-11955T","-11956T","-11957T","-11960T","-11961T","-11962A","-11963T","-11965A","-11966T","-11967T","-11968T","-11970T","-11973A","-11974T","-11975A","-11977T","-11980T","-11981A","-11983A","-11984A","-11985T","-11986A","-11988T","-11989A","-11991A","-11993A","-11994T","-11995T","-11996A","-11997T","-11998T","-12002T","-12003A","-12008T","-12009T","-12010T","-12013A","-12014T","-12015T","-12017T","-12020A","-12021A","-12022A","-12023A","-12024A","-12026A","-12027A","-12028T","-12029T","-12030T","-12031T","-12032A","-12035A","-12036A","-12037A","-12038T","-12040T","-12041A","-12042A","-12043A","-12044T","-12046T","-12047A","-12049A","-12050T","-12052T","-12053T","-12054T","-12055A","-12056T","-12057T","-12059T","-12060A","-12061T","-12063T","-12064A","-12065T","-12066A","-12067A","-12068T","-12070A","-12072T","-12073A","-12074T","-12075T","-12076T","-12077A","-12079A","-12080T","-12081A","-12082A","-12083T","-12085A","-12089A","-12090T","-12091A","-12092A","-12093T","-12094T","-12097T","-12100A","-12102T","-12105A","-12106A","-12108A","-12109T","-12111T","-12112T","-12113A","-12115A","-12116T","-12119T","-12121T","-12122A","-12123T","-12124A","-12125T","-12126A","-12127T","-12129A","-12130A","-12131T","-12132A","-12133A","-12138T","-12140T","-12141T","-12142A","-12143T","-12145T","-12146A","-12147T","-12148T","-12151T","-12152T","-12153T","-12155A","-12156T","-12157T","-12158A","-12159A","-12161A","-12162A","-12163T","-12164T","-12165T","-12166A","-12167A","-12170A","-12171T","-12173T","-12175T","-12176A","-12177T","-12178A","-12179T","-12181T","-12182A","-12183T","-12184A","-12185T","-12187A","-12189A","-12190T","-12192A","-12194T","-12195T","-12196A","-12197A","-12198T","-12199A","-12200T","-12201A","-12202A","-12203T","-12204A","-12205T","-12206T","-12208A","-12209A","-12211A","-12214T","-12216T","-12217A","-12219A","-12220A","-12221T","-12222A","-12224T","-12225T","-12226T","-12227T","-12228T","-12229A","-12230T","-12232T","-12233A","-12234T","-12235A","-12237A","-12238A","G40242A","C40335T","G139582A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A180517-","A180518-","T180519-","A180521-","A180524-","T180525-","A180526-","T180527-","A180528-","A180532-","T180533-","T180534-","-192499A","-192500A","-192502T","-192504A","-192505T","-192506A","-192507A","-192509T","-192510T","-192511A","-192513T","-192514T","-192515A","-192516A","-192518T","-192520A","-192521T","-192522A","-192523A","-192525T","-192526T","-192527A","-192529T","-192530T","-196614A"],"OPG058":["E34K"]},"labels":{"aa":"OPG058: E34K"}},"children":[{"name":"OP642402","node_attrs":{"div":8,"accession":"OP642402","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OP642402/2022-09-12"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-09-12"},"lineage":{"value":"B.1.15"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-24957C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G125388A","G126763A","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-"],"OPG145":["R481H"],"OPG148":["E260K"]},"labels":{"aa":"OPG145: R481H; OPG148: E260K"}}},{"name":"NODE_0000171","node_attrs":{"div":7,"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C127609T"]}},"children":[{"name":"OP390175","node_attrs":{"div":7,"accession":"OP390175","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"strain_display":{"value":"Colombia/OP390175/2022-08-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"date":{"value":"2022-08-02"},"lineage":{"value":"B.1.15"},"country":{"value":"Colombia"},"strain":{"value":"BOL-UNIMOL-MPX-292803-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G180520-","C180522-","G180523-","C180529-","G180530-","G180531-"]}}},{"name":"OP819950","node_attrs":{"div":9,"accession":"OP819950","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"strain_display":{"value":"Colombia/OP819950/2022-10-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-10-12"},"lineage":{"value":"B.1.15"},"country":{"value":"Colombia"},"strain":{"value":"MET_INS_MPX_0956_C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G144284A","C171808T","-180517A","-180518A","-180519T","-180521A","-180524A","-180525T","-180526A","-180527T","-180528A","-180532A","-180533T","-180534T","G196973-","A196974-","A196975-"],"OPG165":["D257N"],"OPG199":["S274L"]},"labels":{"aa":"OPG165: D257N; OPG199: S274L"}}},{"name":"OP693654","node_attrs":{"div":7,"accession":"OP693654","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"strain_display":{"value":"Colombia/OP693654/2022-08-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-08-23"},"lineage":{"value":"B.1.15"},"country":{"value":"Colombia"},"strain":{"value":"DC_INS_MPX_0722_L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A2840-","T2841-","C2842-","G180520-","C180522-","G180523-","C180529-","G180530-","G180531-"]}}},{"name":"OP959066","node_attrs":{"div":7,"accession":"OP959066","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"strain_display":{"value":"Colombia/OP959066/2022-09-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"date":{"value":"2022-09-14"},"lineage":{"value":"B.1.15"},"country":{"value":"Colombia"},"strain":{"value":"CES-UNIMOL-MPX-202203848-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-180517A","-180518A","-180519T","-180521A","-180524A","-180525T","-180526A","-180527T","-180528A","-180532A","-180533T","-180534T"]}}},{"name":"OR086972","node_attrs":{"div":12,"accession":"OR086972","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR086972/2022-07-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-27"},"lineage":{"value":"B.1.15"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_163/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G31180A","C142626T","G158549A","G159341A","C170750T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-180517A","-180518A","-180519T","-180521A","-180524A","-180525T","-180526A","-180527T","-180528A","-180532A","-180533T","-180534T"],"OPG163":["S142L"],"OPG185":["G142E"],"OPG198":["A238V"]},"labels":{"aa":"OPG163: S142L; OPG185: G142E; OPG198: A238V"}}},{"name":"NODE_0000172","node_attrs":{"div":11,"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G47482A","C60062T","G87846A","G125388A","G180520-","C180522-","G180523-","C180529-","G180530-","G180531-"],"OPG080":["E653K"],"OPG145":["R481H"]},"labels":{"aa":"OPG080: E653K; OPG145: R481H"}},"children":[{"name":"OP431400","node_attrs":{"div":11,"accession":"OP431400","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OP431400/2022-08-17"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-08-17"},"lineage":{"value":"B.1.15"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-22751-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP881932","node_attrs":{"div":12,"accession":"OP881932","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OP881932/2022-09-26"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-09-26"},"lineage":{"value":"B.1.15"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-26250"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C165369T","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-"],"OPG190":["S83F"]},"labels":{"aa":"OPG190: S83F"}}}]},{"name":"NODE_0000173","node_attrs":{"div":8,"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C21324T","-180517A","-180518A","-180519T","-180521A","-180524A","-180525T","-180526A","-180527T","-180528A","-180532A","-180533T","-180534T"]}},"children":[{"name":"OR035721","node_attrs":{"div":9,"accession":"OR035721","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035721/2022-10-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1.15"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_115"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G180556A","T196712-","A196713-","T196714-"]}}},{"name":"NODE_0000174","node_attrs":{"div":10,"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C144166T","C181495T"],"OPG210":["S47L"]},"labels":{"aa":"OPG210: S47L"}},"children":[{"name":"OP837479","node_attrs":{"div":11,"accession":"OP837479","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"strain_display":{"value":"Colombia/OP837479/2022-09-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-09-20"},"lineage":{"value":"B.1.15"},"country":{"value":"Colombia"},"strain":{"value":"DC_INS_MPX_1024_L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G68296A"],"OPG085":["S79L"]},"labels":{"aa":"OPG085: S79L"}}},{"name":"OP837477","node_attrs":{"div":11,"accession":"OP837477","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"strain_display":{"value":"Colombia/OP837477/2022-09-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-09-20"},"lineage":{"value":"B.1.15"},"country":{"value":"Colombia"},"strain":{"value":"DC_INS_MPX_0998_L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C173722T","C196935-","T196936-","C196937-"]}}}]}]}]}]}]},{"name":"NODE_0000175","node_attrs":{"div":2,"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G36617A","C159779T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG055":["S156L"],"OPG185":["S288L"]},"labels":{"aa":"OPG055: S156L; OPG185: S288L","clade":"B.1.14"}},"children":[{"name":"ON959135","node_attrs":{"div":4,"accession":"ON959135","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"strain_display":{"value":"USA/ON959135/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.14"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_NY004"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G2132A","G96835A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","C195078T"],"OPG002":["S207L"],"OPG002_dup":["S207L"],"OPG117":["D263N"]},"labels":{"aa":"OPG002: S207L; OPG002_dup: S207L; OPG117: D263N"}}},{"name":"ON694342","node_attrs":{"div":2,"accession":"ON694342","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/ON694342/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.14"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI011"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-606T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-","-196614A"]}}},{"name":"OQ547752","node_attrs":{"div":3,"accession":"OQ547752","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ547752/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.14"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI725"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-606T","C3837T","G150551-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","G181052-"],"OPG209":["G179-"]},"labels":{"aa":"OPG209: G179-"}}},{"name":"OR004152","node_attrs":{"div":6,"accession":"OR004152","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"strain_display":{"value":"USA/OR004152/2022-09-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"Utah Public Health Laboratory, Utah Public Health Laboratory Infectious Disease submission group"},"date":{"value":"2022-09-07"},"lineage":{"value":"B.1.14"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200376/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C25855T","G28021A","C177833T","C177917T"],"OPG042":["E415K"]},"labels":{"aa":"OPG042: E415K"}}},{"name":"OR449706","node_attrs":{"div":6,"accession":"OR449706","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR449706/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.14"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI992"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-606T","C2459T","G90418A","C133943T","C134688T","G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-"],"OPG002":["R98Q"],"OPG111":["E52K"],"OPG193":["F263-"]},"labels":{"aa":"OPG002: R98Q; OPG111: E52K; OPG193: F263-"}}},{"name":"OR086995","node_attrs":{"div":3,"accession":"OR086995","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR086995/2022-08-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-03"},"lineage":{"value":"B.1.14"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_186/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-606T","G146441A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T"],"OPG170":["S113F"]},"labels":{"aa":"OPG170: S113F"}}},{"name":"OX009124","node_attrs":{"div":4,"accession":"OX009124","author":{"author":"Pettke,A.,Filen,F.,Asgeirsson,H.,Glans,H.,Widgren,K.,Muradrasoli,S.,Helgesson,S.,Karlberg,M.L.,Walai,N.,Bjerkner,A.,Gourle,H.,Lindsjo,O.K.,Sonden,K.","value":"Pettke,A.,Filen,F.,Asgeirsson,H.,Glans,H.,Widgren,K.,Muradrasoli,S.,Helgesson,S.,Karlberg,M.L.,Walai,N.,Bjerkner,A.,Gourle,H.,Lindsjo,O.K.,Sonden,K."},"strain_display":{"value":"Sweden/OX009124/2022-05-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Agency of Sweden, Unit for Laboratory Development and Technology Transfer , Folkhalsomyndigheten, 171 82 Solna"},"date":{"value":"2022-05-22"},"lineage":{"value":"B.1.14"},"country":{"value":"Sweden"},"strain":{"value":"Lesion"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T602-","T603-","T604-","T605-","A8055-","A28529-","A28530-","T47054-","T76087-","T88836-","A91705-","A92907-","T103367-","T104687-","T148344A","A148345T","A151680-","A162904-","T163342-","T163597-","A170728-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T"],"OPG044":["K147-"],"OPG113":["I393-"],"OPG178":["T58-"],"OPG188":["K437-"],"OPG189":["F4-"],"OPG198":["K231-"]},"labels":{"aa":"OPG044: K147-; OPG113: I393-; OPG178: T58-; OPG188: K437-; OPG189: F4-; OPG198: K231-"}}},{"name":"ON959133","node_attrs":{"div":2,"accession":"ON959133","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"strain_display":{"value":"USA/ON959133/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.14"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_NY002"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T"]}}},{"name":"OP451009","node_attrs":{"div":2,"accession":"OP451009","author":{"author":"Gigante,C.M.,Pearson,C.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Maloney,M.,Li,Y.","value":"Gigante,C.M.,Pearson,C.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Maloney,M.,Li,Y."},"strain_display":{"value":"USA/OP451009/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.14"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_CT0002"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T173277-","A173278-","T173279-","A173280-","T173281-","A173282-","T173283-","A173284-","T173285-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T"]}}},{"name":"NODE_0000177","node_attrs":{"div":3,"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G171270A","-196614A"],"OPG199":["D95N"]},"labels":{"aa":"OPG199: D95N"}},"children":[{"name":"OP382493","node_attrs":{"div":6,"accession":"OP382493","author":{"author":"Colson,P.","value":"Colson,P."},"strain_display":{"value":"France/OP382493/2022-07-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-22"},"lineage":{"value":"B.1.14"},"country":{"value":"France"},"strain":{"value":"hMPXV-IHU00016"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G25999A","G97417A","G100939A","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T"],"OPG042":["Q367*"],"OPG117":["E457K"]},"labels":{"aa":"OPG042: Q367*; OPG117: E457K"}}},{"name":"OP382492","node_attrs":{"div":4,"accession":"OP382492","author":{"author":"Colson,P.","value":"Colson,P."},"strain_display":{"value":"France/OP382492/2022-07-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-22"},"lineage":{"value":"B.1.14"},"country":{"value":"France"},"strain":{"value":"hMPXV-IHU00015"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G161913A","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","A196856-","A196857-","A196858-"]}}},{"name":"OP605553","node_attrs":{"div":3,"accession":"OP605553","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605553/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.14"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-10-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T594A","-606T","-607T","-608T","-609T","T196950-","A196951-","A196952-"]}}},{"name":"OP555644","node_attrs":{"div":5,"accession":"OP555644","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555644/2022-09-06"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-06"},"lineage":{"value":"B.1.14"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0573/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T594A","-606T","-607T","-608T","-609T","C93713T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G158549A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A","-196616T"]}}}]}]},{"name":"NODE_0000178","node_attrs":{"div":1,"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G111029A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]},"labels":{"clade":"B.1.6"}},"children":[{"name":"OP320554","node_attrs":{"div":3,"accession":"OP320554","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"strain_display":{"value":"Peru/OP320554/2022-07-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"date":{"value":"2022-07-09"},"lineage":{"value":"B.1.6"},"country":{"value":"Peru"},"strain":{"value":"LIM-INS-016"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G25098A","A34289G"]}}},{"name":"OP320551","node_attrs":{"div":1,"accession":"OP320551","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"strain_display":{"value":"Peru/OP320551/2022-07-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"date":{"value":"2022-07-09"},"lineage":{"value":"B.1.6"},"country":{"value":"Peru"},"strain":{"value":"LIM-INS-018"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP320552","node_attrs":{"div":2,"accession":"OP320552","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"strain_display":{"value":"Peru/OP320552/2022-07-06"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"date":{"value":"2022-07-06"},"lineage":{"value":"B.1.6"},"country":{"value":"Peru"},"strain":{"value":"LIM-INS-012"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C96110T"],"OPG117":["S21L"]},"labels":{"aa":"OPG117: S21L"}}},{"name":"OP320553","node_attrs":{"div":1,"accession":"OP320553","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"strain_display":{"value":"Peru/OP320553/2022-07-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"date":{"value":"2022-07-08"},"lineage":{"value":"B.1.6"},"country":{"value":"Peru"},"strain":{"value":"LIM-INS-013"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP320549","node_attrs":{"div":1,"accession":"OP320549","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"strain_display":{"value":"Peru/OP320549/2022-07-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"date":{"value":"2022-07-02"},"lineage":{"value":"B.1.6"},"country":{"value":"Peru"},"strain":{"value":"LIM-INS-010"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP431402","node_attrs":{"div":2,"accession":"OP431402","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OP431402/2022-08-18"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-08-18"},"lineage":{"value":"B.1.6"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-22752-O"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G15814A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP415224","node_attrs":{"div":1,"accession":"OP415224","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415224/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.6"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_3U0idu_9000254"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-"]}}},{"name":"OP693655","node_attrs":{"div":2,"accession":"OP693655","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"strain_display":{"value":"Colombia/OP693655/2022-09-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"date":{"value":"2022-09-03"},"lineage":{"value":"B.1.6"},"country":{"value":"Colombia"},"strain":{"value":"CUN_INS_MPX_0748_L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G165247A","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","T196852-","G196853-","T196854-"]}}},{"name":"OQ696099","node_attrs":{"div":5,"accession":"OQ696099","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OQ696099/2022-11-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-11-09"},"lineage":{"value":"B.1.6"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-30518C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G63811A","G132863A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G167862A","C170130T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"],"OPG193":["D177N"]},"labels":{"aa":"OPG193: D177N"}}},{"name":"OP320550","node_attrs":{"div":1,"accession":"OP320550","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"strain_display":{"value":"Peru/OP320550/2022-07-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"date":{"value":"2022-07-09"},"lineage":{"value":"B.1.6"},"country":{"value":"Peru"},"strain":{"value":"LIM-INS-015"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP289782","node_attrs":{"div":1,"accession":"OP289782","author":{"author":"Silva,I.,Jimenez,V.,Hurtado,V.,Barcena,L.","value":"Silva,I.,Jimenez,V.,Hurtado,V.,Barcena,L."},"strain_display":{"value":"Peru/OP289782/2022-06-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"date":{"value":"2022-06-25"},"lineage":{"value":"B.1.6"},"country":{"value":"Peru"},"strain":{"value":"LIM-INS-001"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-196615A","-196616A","-196617A"]}}},{"name":"OP320548","node_attrs":{"div":1,"accession":"OP320548","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"strain_display":{"value":"Peru/OP320548/2022-07-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"date":{"value":"2022-07-01"},"lineage":{"value":"B.1.6"},"country":{"value":"Peru"},"strain":{"value":"LIM-INS008"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP320555","node_attrs":{"div":1,"accession":"OP320555","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"strain_display":{"value":"Peru/OP320555/2022-07-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"date":{"value":"2022-07-09"},"lineage":{"value":"B.1.6"},"country":{"value":"Peru"},"strain":{"value":"LIM-INS-021"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP289783","node_attrs":{"div":1,"accession":"OP289783","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Mestanza,O.,Lope,P.,Nunez,A.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Mestanza,O.,Lope,P.,Nunez,A."},"strain_display":{"value":"Peru/OP289783/2022-06-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"date":{"value":"2022-06-27"},"lineage":{"value":"B.1.6"},"country":{"value":"Peru"},"strain":{"value":"LIM-INS-003"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000183","node_attrs":{"div":1,"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C70780T"]},"labels":{"clade":"B.1.5"}},"children":[{"name":"OP150925","node_attrs":{"div":1,"accession":"OP150925","author":{"author":"Gigante,C.,Xia,D.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y.","value":"Gigante,C.,Xia,D.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y."},"strain_display":{"value":"USA/OP150925/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.5"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_GA001"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON959175","node_attrs":{"div":1,"accession":"ON959175","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/ON959175/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.5"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI162"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON918656","node_attrs":{"div":5,"accession":"ON918656","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"strain_display":{"value":"Taiwan/ON918656/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.5"},"country":{"value":"Taiwan"},"strain":{"value":"MPXV/human/Taiwan/110-231642/2022"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C28702T","T34793C","T50861C","C51777T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG054":["T402A"],"OPG070":["V91A"],"OPG071":["E888K"]},"labels":{"aa":"OPG054: T402A; OPG070: V91A; OPG071: E888K"}}},{"name":"ON792322","node_attrs":{"div":1,"accession":"ON792322","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"strain_display":{"value":"Switzerland/ON792322/2022-06-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"date":{"value":"2022-06-02"},"lineage":{"value":"B.1.5"},"country":{"value":"Switzerland"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba64538/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON780017","node_attrs":{"div":1,"accession":"ON780017","author":{"author":"Gramigna,G.,Giombini,E.,Gruber,C.E.M.,Rueca,M.,Carletti,F.,Cicalini,S.,Lapa,D.,Puro,V.,Marani,A.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Rivano Capparuccia,M.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F.","value":"Gramigna,G.,Giombini,E.,Gruber,C.E.M.,Rueca,M.,Carletti,F.,Cicalini,S.,Lapa,D.,Puro,V.,Marani,A.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Rivano Capparuccia,M.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F."},"strain_display":{"value":"Italy/ON780017/2022-05-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology"},"date":{"value":"2022-05-21"},"lineage":{"value":"B.1.5"},"country":{"value":"Italy"},"strain":{"value":"INMI-Pt4"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A"]}}},{"name":"OP245318","node_attrs":{"div":5,"accession":"OP245318","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP245318/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1.5"},"country":{"value":"Portugal"},"strain":{"value":"MPX/PT0064/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G71227A","C133867T","C134247T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G158866A"],"OPG090":["E17K"]},"labels":{"aa":"OPG090: E17K"}}},{"name":"OP626134","node_attrs":{"div":6,"accession":"OP626134","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP626134/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.5"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI500"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C22982T","C49265T","C124495T","C150392T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C160312T"],"OPG038":["E60K"],"OPG176":["S195F"]},"labels":{"aa":"OPG038: E60K; OPG176: S195F"}}},{"name":"OP626104","node_attrs":{"div":2,"accession":"OP626104","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP626104/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.5"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI466"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G61213A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG080":["S269L"]},"labels":{"aa":"OPG080: S269L"}}},{"name":"OP783902","node_attrs":{"div":1,"accession":"OP783902","author":{"author":"Laubscher,F.,Marques-Melancia,S.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Marques-Melancia,S.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A."},"strain_display":{"value":"Switzerland/OP783902/2022-06-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"date":{"value":"2022-06-08"},"lineage":{"value":"B.1.5"},"country":{"value":"Switzerland"},"strain":{"value":"hMPXV-CH-38347314/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ319135","node_attrs":{"div":1,"accession":"OQ319135","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ319135/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.5"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI677"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150562-","A150563-","T150564-","G150565-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OQ274886","node_attrs":{"div":1,"accession":"OQ274886","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ274886/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.5"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI667"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OQ274882","node_attrs":{"div":1,"accession":"OQ274882","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ274882/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.5"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI663"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-"]}}},{"name":"NODE_0000184","node_attrs":{"div":2,"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C44333T","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG064":["M522I"]},"labels":{"aa":"OPG064: M522I"}},"children":[{"name":"OR035702","node_attrs":{"div":6,"accession":"OR035702","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035702/2022-05-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-05-30"},"lineage":{"value":"B.1.5"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_96"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C29315T","C60396T","G149807A","C161572T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG046":["D139N"]},"labels":{"aa":"OPG046: D139N"}}},{"name":"NODE_0000185","node_attrs":{"div":3,"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G93512T"],"OPG113":["K594N"]},"labels":{"aa":"OPG113: K594N"}},"children":[{"name":"OP358276","node_attrs":{"div":6,"accession":"OP358276","author":{"author":"Tramuto,F.","value":"Tramuto,F."},"strain_display":{"value":"Italy/OP358276/2022-08-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"University of Palermo, Department of Health Promotion Sciences Maternal and Infant Care, Internal Medicine and Medical Specialties \"G. D'Alessandro\"\"\""},"date":{"value":"2022-08-09"},"lineage":{"value":"B.1.5"},"country":{"value":"Italy"},"strain":{"value":"SIC-AOUP-UNIPA_VL_9aug"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C33103T","C114490T","C133295T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-"],"OPG049":["E17K"],"OPG133":["D403N"]},"labels":{"aa":"OPG049: E17K; OPG133: D403N"}}},{"name":"OR264417","node_attrs":{"div":4,"accession":"OR264417","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264417/2022-06-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-06-22"},"lineage":{"value":"B.1.5"},"country":{"value":"Australia"},"strain":{"value":"43_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G2898A","C194312T"]}}}]}]}]},{"name":"NODE_0000186","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133102-","C148268T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"ON755039","node_attrs":{"div":1,"accession":"ON755039","author":{"author":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O.","value":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O."},"strain_display":{"value":"France/ON755039/2022-05-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"IRBA, D.DNRBC/D.2MI/U.BACT"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"},"country":{"value":"France"},"strain":{"value":"MPXV_IRBA22-11"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133097-","T133098-","T133099-","T133100-","T133101-","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-"]}}},{"name":"OR035703","node_attrs":{"div":2,"accession":"OR035703","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035703/2022-05-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-05-30"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_97"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-133102T","C162521T"],"OPG188":["S309L"]},"labels":{"aa":"OPG188: S309L"}}},{"name":"OR095040","node_attrs":{"div":1,"accession":"OR095040","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR095040/2022-08-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-08"},"lineage":{"value":"B.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_222/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000187","node_attrs":{"div":2,"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G9963A"],"OPG021":["R126K"]},"labels":{"aa":"OPG021: R126K","clade":"B.1.19"}},"children":[{"name":"OP270026","node_attrs":{"div":2,"accession":"OP270026","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/OP270026/2022-07-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1.19"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-4017/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-133102T","-196615A","-196616A","-196617A"]}}},{"name":"OP382481","node_attrs":{"div":4,"accession":"OP382481","author":{"author":"Colson,P.","value":"Colson,P."},"strain_display":{"value":"France/OP382481/2022-07-04"},"host":{"value":"Homo sapiens"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-04"},"lineage":{"value":"B.1.19"},"country":{"value":"France"},"strain":{"value":"hMPXV-IHU00004"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G115549A","C163653T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"],"OPG133":["P50S"]},"labels":{"aa":"OPG133: P50S"}}},{"name":"OP838893","node_attrs":{"div":2,"accession":"OP838893","author":{"author":"Viscardi,M.,Cozzolino,L.,De Martinis,C.,Cardillo,L.,Fusco,G.","value":"Viscardi,M.,Cozzolino,L.,De Martinis,C.,Cardillo,L.,Fusco,G."},"strain_display":{"value":"Italy/OP838893/2022-06-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"Istituto Zooprofilattico Sperimentale del Mezzogiorno, Hanimal Health"},"date":{"value":"2022-06-21"},"lineage":{"value":"B.1.19"},"country":{"value":"Italy"},"strain":{"value":"ID6821"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","T133100-","T133101-","C133103-","G133104-","A133105-","A133106-","T133107-","T133108-","C133109-","A133110-","C133111-","G133112-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A157678-","A157679-","A157680-","A157681-","T157682-","T157683-","T157684-","T157685-","A157686-","A157687-","G157688-","C157689-","G157690-","A157691-","T157692-","G157693-","A157694-","T157695-","A157696-","T163214-","C163215-","T163216-","T163217-","A163218-","T163219-","A163220-","T163221-","A163417-","A163418-","T163419-","T163420-","C163421-","T163422-","T163423-","C163424-","C163425-","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","G174537-","A174538-","T174539-","G174540-","A174541-","A174542-","A180482-","T180483-","T180484-","A180485-","A180486-","A180487-","A180488-","A180489-","A181114-","T181115-","T181116-","C181117-","C181118-","T181119-","T181120-","A181121-","T181122-","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-"],"OPG159":["N124-","Y125-","N126-"],"OPG189":["N29-","S30-","S31-"]},"labels":{"aa":"OPG159: N124-, Y125-, N126-; OPG189: N29-, S30-, S31-"}}},{"name":"OR035726","node_attrs":{"div":4,"accession":"OR035726","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035726/2022-10-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1.19"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_120"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C22739T","-133102T","G133104A","G133231A","T137560-","G164487A"],"OPG038":["E141K"]},"labels":{"aa":"OPG038: E141K"}}},{"name":"NODE_0000188","node_attrs":{"div":3,"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-133102T","G150003A"]}},"children":[{"name":"OP382486","node_attrs":{"div":6,"accession":"OP382486","author":{"author":"Colson,P.","value":"Colson,P."},"strain_display":{"value":"France/OP382486/2022-07-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-07"},"lineage":{"value":"B.1.19"},"country":{"value":"France"},"strain":{"value":"hMPXV-IHU00009"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C38483T","C164272T","G175971A","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"],"OPG189":["R314C"],"OPG205":["E106K"]},"labels":{"aa":"OPG189: R314C; OPG205: E106K"}}},{"name":"OP555643","node_attrs":{"div":6,"accession":"OP555643","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555643/2022-09-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-05"},"lineage":{"value":"B.1.19"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0572/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C55057T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A169944T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C185326T","-196615A"],"OPG073":["E29K"],"OPG197":["E92V"],"OPG210":["S1324L"]},"labels":{"aa":"OPG073: E29K; OPG197: E92V; OPG210: S1324L"}}},{"name":"OQ172215","node_attrs":{"div":7,"accession":"OQ172215","author":{"author":"Zeggagh,J.,Ferraris,O.,Salmona,M.,Tarantola,A.,Molina,J.M.,Delaugerre,C.","value":"Zeggagh,J.,Ferraris,O.,Salmona,M.,Tarantola,A.,Molina,J.M.,Delaugerre,C."},"strain_display":{"value":"France/OQ172215/2022-06-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"Hopital Saint Louis, Paris"},"date":{"value":"2022-06-07"},"lineage":{"value":"B.1.19"},"country":{"value":"France"},"strain":{"value":"MPXV-1047"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A2591G","A31053G","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133171-","C133172-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T133639-","A150635-","A152676-","T152686-","T155897A","C173533A","A179077T","A179079T","A179081T","C179082T","A179083T","A179086T","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T194619C","T194627G"],"OPG002":["F54S"],"OPG002_dup":["F54S","C57G"],"OPG047":["C48R"]},"labels":{"aa":"OPG002: F54S; OPG002_dup: F54S, C57G; OPG047: C48R"}}},{"name":"NODE_0000189","node_attrs":{"div":4,"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C74417T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG094":["S213L"]},"labels":{"aa":"OPG094: S213L"}},"children":[{"name":"OP536803","node_attrs":{"div":5,"accession":"OP536803","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536803/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.19"},"country":{"value":"United Kingdom"},"strain":{"value":"9000431"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C22179T","G190782-","A190783-","A190784-","A190785-","A196614-"],"OPG016":["E125-","I126-"]},"labels":{"aa":"OPG016: E125-, I126-"}}},{"name":"NODE_0000190","node_attrs":{"div":5,"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C62868T"]}},"children":[{"name":"OP536782","node_attrs":{"div":5,"accession":"OP536782","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536782/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.19"},"country":{"value":"United Kingdom"},"strain":{"value":"9000406"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP536781","node_attrs":{"div":5,"accession":"OP536781","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536781/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.19"},"country":{"value":"United Kingdom"},"strain":{"value":"9000405"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","A196614-"]}}}]},{"name":"NODE_0000191","node_attrs":{"div":5,"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C177833T","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}},"children":[{"name":"OP555661","node_attrs":{"div":7,"accession":"OP555661","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555661/2022-09-15"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-15"},"lineage":{"value":"B.1.19"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0594/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G109880A","G126842A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-"],"OPG148":["R286K"]},"labels":{"aa":"OPG148: R286K"}}},{"name":"OP555617","node_attrs":{"div":8,"accession":"OP555617","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555617/2022-08-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-27"},"lineage":{"value":"B.1.19"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0546/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C18602T","C112551T","G174045A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-"],"OPG031":["R76K"]},"labels":{"aa":"OPG031: R76K"}}}]}]}]}]}]},{"name":"NODE_0000192","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C18133T"]}},"children":[{"name":"OP324453","node_attrs":{"div":3,"accession":"OP324453","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP324453/2022-07-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-12"},"lineage":{"value":"B.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0129/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","G149818A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G151362A","-196615A","-196616T"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG176":["D4N"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG176: D4N"}}},{"name":"NODE_0000193","node_attrs":{"div":4,"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G67611A","G130231A","G159277A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG185":["E121K"]},"labels":{"aa":"OPG185: E121K","clade":"B.1.11"}},"children":[{"name":"OP169336","node_attrs":{"div":4,"accession":"OP169336","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OP169336/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.11"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-070499/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A"]}}},{"name":"OP431825","node_attrs":{"div":4,"accession":"OP431825","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"strain_display":{"value":"USA/OP431825/2022-08-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"date":{"value":"2022-08-07"},"lineage":{"value":"B.1.11"},"country":{"value":"USA"},"strain":{"value":"MPXV22/human/USA-NE-127"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A","-196616A","-196617A"]}}},{"name":"OP390178","node_attrs":{"div":4,"accession":"OP390178","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"strain_display":{"value":"Colombia/OP390178/2022-08-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"date":{"value":"2022-08-20"},"lineage":{"value":"B.1.11"},"country":{"value":"Colombia"},"strain":{"value":"MAG-UNIMOL-MPX-292982-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP536736","node_attrs":{"div":4,"accession":"OP536736","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"strain_display":{"value":"USA/OP536736/2022-07-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"date":{"value":"2022-07-01"},"lineage":{"value":"B.1.11"},"country":{"value":"USA"},"strain":{"value":"MPXV-USA-IL-IDPH-075"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A","-196616A","-196617A"]}}},{"name":"OP642421","node_attrs":{"div":5,"accession":"OP642421","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OP642421/2022-09-03"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-09-03"},"lineage":{"value":"B.1.11"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-25510E"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C90842T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG111":["S193F"]},"labels":{"aa":"OPG111: S193F"}}},{"name":"OQ148469","node_attrs":{"div":7,"accession":"OQ148469","author":{"author":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"strain_display":{"value":"Colombia/OQ148469/2022-11-11"},"host":{"value":"Homo sapiens"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"date":{"value":"2022-11-11"},"lineage":{"value":"B.1.11"},"country":{"value":"Colombia"},"strain":{"value":"LBMB-UTP_MP-013_VAC"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C29040T","G128544A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","G182189A"],"OPG045":["D75N"],"OPG150":["D256N"]},"labels":{"aa":"OPG045: D75N; OPG150: D256N"}}},{"name":"OP959062","node_attrs":{"div":4,"accession":"OP959062","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"strain_display":{"value":"Colombia/OP959062/2022-11-11"},"host":{"value":"Homo sapiens"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"date":{"value":"2022-11-11"},"lineage":{"value":"B.1.11"},"country":{"value":"Colombia"},"strain":{"value":"BOL-UNIMOL-MPX-293614-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP890529","node_attrs":{"div":6,"accession":"OP890529","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OP890529/2022-10-26"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-10-26"},"lineage":{"value":"B.1.11"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00324/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A763-","A764-","T765-","G39327A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177273A","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-"],"OPG057":["A290V"],"OPG205":["D540N"]},"labels":{"aa":"OPG057: A290V; OPG205: D540N"}}},{"name":"OQ348850","node_attrs":{"div":5,"accession":"OQ348850","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"strain_display":{"value":"USA/OQ348850/2022-07-06"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2022-07-06"},"lineage":{"value":"B.1.11"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000101/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T6976-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","A140155T","A140156G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C151439T"],"OPG159":["N130C"]},"labels":{"aa":"OPG159: N130C"}}},{"name":"OQ696092","node_attrs":{"div":8,"accession":"OQ696092","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OQ696092/2022-11-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-11-03"},"lineage":{"value":"B.1.11"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-29706O"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G17023A","G74462A","C80742T","G113382A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","T196988-","A196989-","A196990-"],"OPG029":["S16F"],"OPG094":["R228K"],"OPG104":["R93Q"]},"labels":{"aa":"OPG029: S16F; OPG094: R228K; OPG104: R93Q"}}},{"name":"OQ696094","node_attrs":{"div":7,"accession":"OQ696094","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OQ696094/2022-11-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-11-08"},"lineage":{"value":"B.1.11"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-30087C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C42840T","C55000T","G67730A","C196739-","T196740-","T196741-"],"OPG073":["E48K"],"OPG085":["R268C"]},"labels":{"aa":"OPG073: E48K; OPG085: R268C"}}},{"name":"OR209310","node_attrs":{"div":7,"accession":"OR209310","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"strain_display":{"value":"USA/OR209310/2022-12-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-12-XX"},"lineage":{"value":"B.1.11"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_TX0052"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G19458A","G74374A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C185455T"],"OPG034":["S183L"],"OPG094":["E199K"],"OPG210":["S1367L"]},"labels":{"aa":"OPG034: S183L; OPG094: E199K; OPG210: S1367L"}}},{"name":"NODE_0000194","node_attrs":{"div":5,"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C89777T"],"OPG110":["P49L"]},"labels":{"aa":"OPG110: P49L"}},"children":[{"name":"OQ320509","node_attrs":{"div":7,"accession":"OQ320509","author":{"author":"Gigante,C.,Goldoft,M.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Holshue,M.,Li,Y.","value":"Gigante,C.,Goldoft,M.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Holshue,M.,Li,Y."},"strain_display":{"value":"USA/OQ320509/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.11"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_WA0016"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G23118A","G168669A","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A"],"OPG195":["R147K"]},"labels":{"aa":"OPG195: R147K"}}},{"name":"OR427333","node_attrs":{"div":5,"accession":"OR427333","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OR427333/2022-12-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-12-XX"},"lineage":{"value":"B.1.11"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-129402/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000195","node_attrs":{"div":5,"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C35308T"],"OPG054":["R230H"]},"labels":{"aa":"OPG054: R230H"}},"children":[{"name":"OQ957072","node_attrs":{"div":7,"accession":"OQ957072","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OQ957072/2023-02-16"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2023-02-16"},"lineage":{"value":"B.1.11"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-3668E"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G71777A","C120979T"],"OPG138":["D52N"]},"labels":{"aa":"OPG138: D52N"}}},{"name":"OQ696093","node_attrs":{"div":8,"accession":"OQ696093","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OQ696093/2022-11-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-11-03"},"lineage":{"value":"B.1.11"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-29778O"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G17023A","G102395A","G148319A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG029":["S16F"]},"labels":{"aa":"OPG029: S16F"}}}]}]}]},{"name":"NODE_0000196","node_attrs":{"div":2,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C89906T","G94798A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG110":["S92F"],"OPG115":["E47K"]},"labels":{"aa":"OPG110: S92F; OPG115: E47K","clade":"B.1.10"}},"children":[{"name":"ON720848","node_attrs":{"div":3,"accession":"ON720848","author":{"author":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"strain_display":{"value":"Spain/ON720848/2022-05-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"Microbial Genomics, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"},"date":{"value":"2022-05-27"},"lineage":{"value":"B.1.10"},"country":{"value":"Spain"},"strain":{"value":"MpxV/Spain/MD-HGUGM-6513479/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A327-","T605-","T606-","A1697-","T4296-","T6587-","T6588-","T7253-","G7724-","T8017-","A8036-","T8499-","T9514-","A9869-","T10502-","A10914-","T11188-","C11749-","T11761-","T12121-","A15754-","A17087-","T18866-","A19360-","T20663-","A21081-","T21975-","T24678-","T25853-","T26099-","C27002-","A27114-","C27799-","A28529-","A28530-","T32194-","T33414-","G35949-","T37982-","T39131-","T39866-","T41744-","T42990-","C43014-","G43200-","A43443-","T44120-","T44738-","G46762-","T48675-","A49134-","G49833-","A51022-","A52765-","A54968-","A55124-","T55560-","T56040-","T57075-","A57277-","A58650-","T61749-","A62041-","T63628-","A64728-","A64935-","A65535-","A65967-","T66783-","A66843-","A67164-","C68466-","T68481-","C68899-","G69145-","A69744-","T69768-","A71254-","G71359-","T75833-","A76072-","T76084-","T76085-","A76153-","A76154-","A76890-","A77260-","T77803-","T78062-","A79042-","A79181-","G79217-","C79533T","A79787-","G80950-","C82482-","T84846-","T88095-","T88836-","T88941-","A89106-","T90646-","T91129-","T91370-","A91583-","A91705-","T94795-","A95341-","A95574-","G95742-","G95818-","A97351-","A97480-","A97501-","A97699-","A98683-","T101452-","G101515-","T102437-","T103367-","T103368-","T104279-","T105360-","T106596-","T108598-","A113921-","T113951-","C114431-","T114518-","T114755-","T115127-","G115801-","A116014-","C116494-","T116963-","T121121-","T121122-","G121269-","C121546-","T124022-","T124751-","A125252-","A126568-","T126682-","A126715-","A127250-","A127754-","A132023-","A132024-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133639-","T136780-","T137886-","A143045-","G143363-","T143478-","A144230-","T146131-","A148000-","A149727-","A150340-","T150538-","T150539-","A150635-","T150864-","A151490-","A151508-","G151545-","A152676-","T152686-","A153358-","A153424-","A153517-","T154862-","T155424-","C156607-","C156608-","A157997-","T163498-","T163597-","A163957-","A165461-","A166740-","G167640-","A167967-","T168120-","A170728-","T170758-","T170903-","T170904-","T172087-","T172667-","G179036-","A179551-","A179950-","T180905-","G181052-","A181253-","C183534-","A183780-","T187080-","A190935-","A191015-","G191519-","A196613-","A196614-","T196888-","T197183-"],"OPG015_dup":["G156-"],"OPG016":["T176-"],"OPG019":["G49-"],"OPG021":["N95-"],"OPG023":["G385-"],"OPG043":["G53-"],"OPG044":["K147-"],"OPG066":["P223-"],"OPG068":["L159-","D545-"],"OPG070":["N145-"],"OPG074":["K523-"],"OPG084":["K3-","K272-","R416-"],"OPG085":["F457-"],"OPG087":["L15-","G97-"],"OPG090":["K26-"],"OPG096":["L83-"],"OPG098":["S121-"],"OPG099":["F47-"],"OPG100":["F19-"],"OPG102":["K33-"],"OPG104":["P24-"],"OPG109":["K206-"],"OPG111":["F128-"],"OPG112":["S42-"],"OPG115":["S46-"],"OPG116":["K72-"],"OPG117":["K435-","N478-","R551-"],"OPG118":["I80-"],"OPG122":["Y4-"],"OPG123":["K569-"],"OPG133":["K394-"],"OPG134":["E18-","P249-"],"OPG139":["P34-"],"OPG145":["F26-","F269-","I436-"],"OPG148":["I195-","F233-"],"OPG149":["K19-"],"OPG151":["K1034-"],"OPG164":["R90-"],"OPG165":["M239-"],"OPG172":["I192-"],"OPG175":["N96-"],"OPG176":["K178-"],"OPG178":["D13-"],"OPG180":["K223-","K276-"],"OPG181":["F151-"],"OPG189":["L56-","K209-"],"OPG190":["N114-"],"OPG192":["K4-"],"OPG193":["G103-","F263-"],"OPG198":["K231-"],"OPG208":["I96-"],"OPG209":["L130-"],"OPG210":["P727-"]},"labels":{"aa":"OPG015_dup: G156-; OPG016: T176-; OPG019: G49-; OPG021: N95-; OPG023: G385-; OPG043: G53-; OPG044: K147-; OPG066: P223-; OPG068: L159-, D545-; OPG070: N145-; OPG074: K523-; OPG084: K3-, K272-, R416-; OPG085: F457-; OPG087: L15-, G97-; OPG090: K26-; OPG096: L83-; OPG098: S121-; OPG099: F47-; OPG100: F19-; OPG102: K33-; OPG104: P24-; OPG109: K206-; OPG111: F128-; OPG112: S42-; OPG115: S46-; OPG116: K72-; OPG117: K435-, N478-, R551-; OPG118: I80-; OPG122: Y4-; OPG123: K569-; OPG133: K394-; OPG134: E18-, P249-; OPG139: P34-; OPG145: F26-, F269-, I436-; OPG148: I195-, F233-; OPG149: K19-; OPG151: K1034-; OPG164: R90-; OPG165: M239-; OPG172: I192-; OPG175: N96-; OPG176: K178-; OPG178: D13-; OPG180: K223-, K276-; OPG181: F151-; OPG189: L56-, K209-; OPG190: N114-; OPG192: K4-; OPG193: G103-, F263-; OPG198: K231-; OPG208: I96-; OPG209: L130-; OPG210: P727-"}}},{"name":"OP245334","node_attrs":{"div":4,"accession":"OP245334","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP245334/2022-07-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-23"},"lineage":{"value":"B.1.10"},"country":{"value":"Portugal"},"strain":{"value":"MPX/PT0081/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-609T","G610-","T611-","C120237T","G126047A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A196619-","T196620-"],"OPG148":["R21K"]},"labels":{"aa":"OPG148: R21K"}}},{"name":"OP205110","node_attrs":{"div":2,"accession":"OP205110","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205110/2022-06-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-14"},"lineage":{"value":"B.1.10"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000147"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OQ581847","node_attrs":{"div":15,"accession":"OQ581847","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"strain_display":{"value":"Spain/OQ581847/2022-07-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"date":{"value":"2022-07-01"},"lineage":{"value":"B.1.10"},"country":{"value":"Spain"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0005b/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A43453G","A66769C","T88735A","G90070A","C101656T","G104325A","C121681T","G127869A","G132490A","T133095A","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T139779C","G140866T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C151204T","T176743A"],"OPG063":["L79P"],"OPG085":["V588G"],"OPG109":["E238V"],"OPG110":["D147N"],"OPG123":["A249V"],"OPG150":["G31R"],"OPG160":["S70Y"],"OPG205":["L363*"]},"labels":{"aa":"OPG063: L79P; OPG085: V588G; OPG109: E238V; OPG110: D147N; OPG123: A249V; OPG150: G31R; OPG160: S70Y; OPG205: L363*"}}},{"name":"OR264420","node_attrs":{"div":3,"accession":"OR264420","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264420/2022-07-10"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-10"},"lineage":{"value":"B.1.10"},"country":{"value":"Australia"},"strain":{"value":"45_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G63147A","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"NODE_0000197","node_attrs":{"div":3,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C150831T"]}},"children":[{"name":"ON959143","node_attrs":{"div":4,"accession":"ON959143","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O."},"strain_display":{"value":"Finland/ON959143/2022-06-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"date":{"value":"2022-06-16"},"lineage":{"value":"B.1.10"},"country":{"value":"Finland"},"strain":{"value":"MPX-96/Finland/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C188491T"]}}},{"name":"OP382489","node_attrs":{"div":4,"accession":"OP382489","author":{"author":"Colson,P.","value":"Colson,P."},"strain_display":{"value":"France/OP382489/2022-07-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-19"},"lineage":{"value":"B.1.10"},"country":{"value":"France"},"strain":{"value":"hMPXV-IHU00012"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G109437A","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","G150603-","A150604-","T150605-","A150606-","T150607-","G150608-","A150609-","T150610-","G150611-"],"OPG129":["S523L"],"OPG153":["D384-","D385-"]},"labels":{"aa":"OPG129: S523L; OPG153: D384-, D385-"}}}]},{"name":"NODE_0000198","node_attrs":{"div":3,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G50672A"],"OPG070":["R28K"]},"labels":{"aa":"OPG070: R28K"}},"children":[{"name":"OP642387","node_attrs":{"div":3,"accession":"OP642387","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OP642387/2022-09-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-09-09"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-24914-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP642422","node_attrs":{"div":4,"accession":"OP642422","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OP642422/2022-09-14"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-09-14"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-25511E"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C55024T","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-"],"OPG073":["E40K"]},"labels":{"aa":"OPG073: E40K"}}},{"name":"OP642408","node_attrs":{"div":3,"accession":"OP642408","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OP642408/2022-09-13"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-09-13"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-25285O"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-"]}}},{"name":"OQ261707","node_attrs":{"div":4,"accession":"OQ261707","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OQ261707/2022-10-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-10-14"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-28354C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G148202A"],"OPG173":["E56K"]},"labels":{"aa":"OPG173: E56K"}}},{"name":"OQ148472","node_attrs":{"div":5,"accession":"OQ148472","author":{"author":"Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"strain_display":{"value":"Colombia/OQ148472/2022-11-11"},"host":{"value":"Homo sapiens"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"date":{"value":"2022-11-11"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"LBMB-UTP_MP-019_VAC"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C25087T","C62649T"],"OPG040":["R131K"]},"labels":{"aa":"OPG040: R131K"}}},{"name":"OQ696076","node_attrs":{"div":6,"accession":"OQ696076","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OQ696076/2022-10-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-10-21"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-29391C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G109844A","C156429T","G177522A"],"OPG205":["E623K"]},"labels":{"aa":"OPG205: E623K"}}},{"name":"NODE_0000199","node_attrs":{"div":4,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C13624T","-179194A","-179195T"]}},"children":[{"name":"OP689664","node_attrs":{"div":5,"accession":"OP689664","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP689664/2022-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1.10"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI511"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C43472T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG063":["E73K"]},"labels":{"aa":"OPG063: E73K"}}},{"name":"OP642403","node_attrs":{"div":5,"accession":"OP642403","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OP642403/2022-09-13"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-09-13"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-25254C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C120170T","G133051A","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-"],"OPG137":["S190L"]},"labels":{"aa":"OPG137: S190L"}}}]},{"name":"NODE_0000200","node_attrs":{"div":4,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G68499A"]}},"children":[{"name":"OQ261709","node_attrs":{"div":6,"accession":"OQ261709","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OQ261709/2022-10-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-10-21"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-28766E"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C15945T","C158835T","A197010-","T197011-","G197012-"],"OPG027":["D145N"]},"labels":{"aa":"OPG027: D145N"}}},{"name":"OQ261701","node_attrs":{"div":4,"accession":"OQ261701","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OQ261701/2022-10-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-10-13"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-28290C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","A197133-","T197134-","T197135-"]}}}]},{"name":"NODE_0000201","node_attrs":{"div":5,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G45416A","C123118T","A181356-","T181357-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","A181366-","A181368-","A181369-","A181370-","T181371-","T181372-"]}},"children":[{"name":"OP642417","node_attrs":{"div":5,"accession":"OP642417","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OP642417/2022-09-13"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-09-13"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-25431E"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C181355-","G181358-","C181365-","G181367-"]}}},{"name":"NODE_0000202","node_attrs":{"div":8,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G32863A","C72770T","C148771T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","-181356A","-181357T","-181359A","-181360A","-181361T","-181362T","-181363T","-181364T","-181366A","-181368A","-181369A","-181370A","-181371T","-181372T"],"OPG092":["E60K"],"OPG174":["D209N"]},"labels":{"aa":"OPG092: E60K; OPG174: D209N"}},"children":[{"name":"OQ696103","node_attrs":{"div":8,"accession":"OQ696103","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OQ696103/2022-11-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-11-22"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-31501C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OQ696098","node_attrs":{"div":11,"accession":"OQ696098","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OQ696098/2022-11-10"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-11-10"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-30513C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","A50672G","C67823T","A94798G"],"OPG070":["K28R"],"OPG085":["E237K"],"OPG115":["K47E"]},"labels":{"aa":"OPG070: K28R; OPG085: E237K; OPG115: K47E"}}}]}]},{"name":"NODE_0000203","node_attrs":{"div":4,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C49265T","A180517-","A180518-","T180519-","A180521-","A180524-","T180525-","A180526-","T180527-","A180528-","A180532-","T180533-","T180534-"]}},"children":[{"name":"OP459217","node_attrs":{"div":7,"accession":"OP459217","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OP459217/2022-08-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"date":{"value":"2022-08-30"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-23654-O"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C113965T","G150800A","C152191T","G180520-","C180522-","G180523-","C180529-","G180530-","G180531-"],"OPG133":["E578K"]},"labels":{"aa":"OPG133: E578K"}}},{"name":"OP459218","node_attrs":{"div":4,"accession":"OP459218","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OP459218/2022-08-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"date":{"value":"2022-08-30"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-23655-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G180520-","C180522-","G180523-","C180529-","G180530-","G180531-"]}}},{"name":"OQ261695","node_attrs":{"div":7,"accession":"OQ261695","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OQ261695/2022-10-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-10-12"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-28157C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A1701-","C1702-","T1703-","G7959A","C19990T","G164476A","-180517A","-180518A","-180519T","-180521A","-180524A","-180525T","-180526A","-180527T","-180528A","-180532A","-180533T","-180534T","T196852-","G196853-","T196854-"],"OPG019":["R127Q"],"OPG034":["D6N"],"OPG189":["E382K"]},"labels":{"aa":"OPG019: R127Q; OPG034: D6N; OPG189: E382K"}}},{"name":"OP959057","node_attrs":{"div":5,"accession":"OP959057","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"strain_display":{"value":"Colombia/OP959057/2022-11-10"},"host":{"value":"Homo sapiens"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"date":{"value":"2022-11-10"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"SUC-UNIMOL-MPX-293401-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G23118A","-180517A","-180518A","-180519T","-180521A","-180524A","-180525T","-180526A","-180527T","-180528A","-180532A","-180533T","-180534T"]}}},{"name":"OQ696105","node_attrs":{"div":8,"accession":"OQ696105","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OQ696105/2022-11-24"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-11-24"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-31875C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C6819T","G33823A","G38820A","C158040T","-180517A","-180518A","-180519T","-180521A","-180524A","-180525T","-180526A","-180527T","-180528A","-180532A","-180533T","-180534T"],"OPG052":["S58L"],"OPG056":["S72L"]},"labels":{"aa":"OPG052: S58L; OPG056: S72L"}}},{"name":"NODE_0000204","node_attrs":{"div":5,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C100007T"],"OPG118":["S521F"]},"labels":{"aa":"OPG118: S521F"}},"children":[{"name":"OP536764","node_attrs":{"div":5,"accession":"OP536764","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536764/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.10"},"country":{"value":"United Kingdom"},"strain":{"value":"9000385"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-180517A","-180518A","-180519T","-180521A","-180524A","-180525T","-180526A","-180527T","-180528A","-180532A","-180533T","-180534T","A196614-"]}}},{"name":"OP477453","node_attrs":{"div":5,"accession":"OP477453","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OP477453/2022-08-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-08-23"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-23188-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G180520-","C180522-","G180523-","C180529-","G180530-","G180531-"]}}},{"name":"OP642373","node_attrs":{"div":5,"accession":"OP642373","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OP642373/2022-09-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-09-08"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-24717-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G180520-","C180522-","G180523-","C180529-","G180530-","G180531-"]}}},{"name":"OQ261712","node_attrs":{"div":5,"accession":"OQ261712","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"strain_display":{"value":"Colombia/OQ261712/2022-10-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"date":{"value":"2022-10-21"},"lineage":{"value":"B.1.10"},"country":{"value":"Colombia"},"strain":{"value":"ANT-LDSP-ANT-MPX-28828C"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-180517A","-180518A","-180519T","-180521A","-180524A","-180525T","-180526A","-180527T","-180528A","-180532A","-180533T","-180534T","T196852-","G196853-","T196854-"]}}}]}]}]}]},{"name":"NODE_0000205","node_attrs":{"div":1,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G34308A"],"OPG053":["S128L"]},"labels":{"aa":"OPG053: S128L","clade":"B.1.4"}},"children":[{"name":"ON880519","node_attrs":{"div":2,"accession":"ON880519","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"strain_display":{"value":"Canada/ON880519/2022-05-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-13"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-2833/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T85846C"],"OPG107":["M112T"]},"labels":{"aa":"OPG107: M112T"}}},{"name":"OR759208","node_attrs":{"div":3,"accession":"OR759208","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759208/2022-07-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-07-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL120/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T12530G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C176447T"],"OPG023":["E124A"]},"labels":{"aa":"OPG023: E124A"}}},{"name":"NODE_0000206","node_attrs":{"div":6,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G648-","A649-","T650-","C25967T","G36259A","C97805T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C172792T","G174543A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG042":["W377*"],"OPG117":["P586L"]},"labels":{"aa":"OPG042: W377*; OPG117: P586L"}},"children":[{"name":"OP748954","node_attrs":{"div":6,"accession":"OP748954","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OP748954/2022-09-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-09-30"},"lineage":{"value":"B.1.4"},"country":{"value":"USA"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00268/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP920681","node_attrs":{"div":6,"accession":"OP920681","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"strain_display":{"value":"USA/OP920681/2022-11-10"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-11-10"},"lineage":{"value":"B.1.4"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00343/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A763-","A764-","T765-"]}}}]},{"name":"NODE_0000207","node_attrs":{"div":4,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C10672T","G112481A","G163626A"],"OPG022":["E63K"]},"labels":{"aa":"OPG022: E63K"}},"children":[{"name":"OP279041","node_attrs":{"div":4,"accession":"OP279041","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"strain_display":{"value":"Canada/OP279041/2022-06-29"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-29"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-4125/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"]}}},{"name":"NODE_0000208","node_attrs":{"div":5,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A87705G"]}},"children":[{"name":"OP279049","node_attrs":{"div":5,"accession":"OP279049","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"strain_display":{"value":"Canada/OP279049/2022-07-04"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-07-04"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-4119/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133414-","A133415-","C133416-","A133417-","A133418-","T133419-","C133420-","A133421-","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR126132","node_attrs":{"div":8,"accession":"OR126132","author":{"author":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C.","value":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C."},"strain_display":{"value":"Spain/OR126132/2023-03-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"Hospital Ramon y Cajal, Microbiology"},"date":{"value":"2023-03-23"},"lineage":{"value":"B.1.4"},"country":{"value":"Spain"},"strain":{"value":"HRYC_MPXV002"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G6376A","G11924A","G21674A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C190834T"],"OPG016":["S142L"],"OPG023":["S326L"],"OPG037":["L254F"]},"labels":{"aa":"OPG016: S142L; OPG023: S326L; OPG037: L254F"}}},{"name":"OR759209","node_attrs":{"div":5,"accession":"OR759209","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759209/2022-07-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-07-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL121/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000209","node_attrs":{"div":6,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C99441T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}},"children":[{"name":"OR759175","node_attrs":{"div":7,"accession":"OR759175","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759175/2022-09-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL087/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C111569T"],"OPG130":["D112N"]},"labels":{"aa":"OPG130: D112N"}}},{"name":"OR759153","node_attrs":{"div":8,"accession":"OR759153","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759153/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL061/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C153642T","C183429T"],"OPG210":["P692S"]},"labels":{"aa":"OPG210: P692S"}}}]}]},{"name":"NODE_0000210","node_attrs":{"div":5,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G144478A"]}},"children":[{"name":"ON880511","node_attrs":{"div":5,"accession":"ON880511","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"strain_display":{"value":"Canada/ON880511/2022-05-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-30"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-3214/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP279047","node_attrs":{"div":5,"accession":"OP279047","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"strain_display":{"value":"Canada/OP279047/2022-07-04"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-07-04"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-4152/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP752106","node_attrs":{"div":8,"accession":"OP752106","author":{"author":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Morrison,S.S.,Desch,M.,Knipe,K.,Weigand,M.R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Morrison,S.S.,Desch,M.,Knipe,K.,Weigand,M.R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y."},"strain_display":{"value":"USA/OP752106/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.4"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_FL0025"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C57339T","T173285-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","G176716A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","G185991A"],"OPG075":["E54K"],"OPG205":["G354D"],"OPG210":["D1546N"]},"labels":{"aa":"OPG075: E54K; OPG205: G354D; OPG210: D1546N"}}},{"name":"OR759222","node_attrs":{"div":8,"accession":"OR759222","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759222/2022-07-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-07-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL134/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G60855A","C115787G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A186904G"],"OPG134":["S13C"],"OPG210":["Y1850C"]},"labels":{"aa":"OPG134: S13C; OPG210: Y1850C"}}},{"name":"NODE_0000211","node_attrs":{"div":6,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C143461T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}},"children":[{"name":"OP279040","node_attrs":{"div":7,"accession":"OP279040","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"strain_display":{"value":"Canada/OP279040/2022-07-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-07-03"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-4122/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G82868A","A150627-","T150628-","A150629-","A150630-","A150631-","A150632-","A150633-","A150634-","A150635-","T150636-","A150637-","T150638-","A150639-","A150640-","T150641-","T150642-","G150643-","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR759212","node_attrs":{"div":6,"accession":"OR759212","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759212/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL124/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","A196614-"]}}}]},{"name":"NODE_0000212","node_attrs":{"div":6,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G170076A"]}},"children":[{"name":"OR759176","node_attrs":{"div":8,"accession":"OR759176","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759176/2022-09-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL088/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C128534T","C151626T"],"OPG178":["Q40*"]},"labels":{"aa":"OPG178: Q40*"}}},{"name":"OR759174","node_attrs":{"div":6,"accession":"OR759174","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759174/2022-09-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL086/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000213","node_attrs":{"div":6,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C4150T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G193060A"],"OPG003":["S153N"],"OPG003_dup":["S153N"]},"labels":{"aa":"OPG003: S153N; OPG003_dup: S153N"}},"children":[{"name":"OR759168","node_attrs":{"div":6,"accession":"OR759168","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759168/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL080/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR759171","node_attrs":{"div":7,"accession":"OR759171","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759171/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL083/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C59492T"],"OPG079":["E44K"]},"labels":{"aa":"OPG079: E44K"}}}]}]}]},{"name":"NODE_0000214","node_attrs":{"div":5,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C24995T","G85774A","G148427A","G189258A"],"OPG040":["D162N"],"OPG107":["R88K"]},"labels":{"aa":"OPG040: D162N; OPG107: R88K"}},"children":[{"name":"ON983167","node_attrs":{"div":5,"accession":"ON983167","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"strain_display":{"value":"Canada/ON983167/2022-06-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-16"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-3725/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"ON983163","node_attrs":{"div":5,"accession":"ON983163","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"strain_display":{"value":"Canada/ON983163/2022-06-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-07"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-3532/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"ON983164","node_attrs":{"div":6,"accession":"ON983164","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"strain_display":{"value":"Canada/ON983164/2022-06-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-09"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-3558/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G167106A"],"OPG192":["E126K"]},"labels":{"aa":"OPG192: E126K"}}},{"name":"ON880515","node_attrs":{"div":5,"accession":"ON880515","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"strain_display":{"value":"Canada/ON880515/2022-06-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-02"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-3467/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"ON880507","node_attrs":{"div":5,"accession":"ON880507","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"strain_display":{"value":"Canada/ON880507/2022-05-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-05-27"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-3071/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP279048","node_attrs":{"div":6,"accession":"OP279048","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"strain_display":{"value":"Canada/OP279048/2022-06-29"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"date":{"value":"2022-06-29"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"MpxV/human/CAN/UN-NML-4155/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C120198T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ427147","node_attrs":{"div":6,"accession":"OQ427147","author":{"author":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"strain_display":{"value":"USA/OQ427147/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.4"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_IL0006"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G131810A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG151":["D963N"]},"labels":{"aa":"OPG151: D963N"}}},{"name":"OR759226","node_attrs":{"div":7,"accession":"OR759226","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759226/2022-07-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-07-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL140/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G20145A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G189924A"],"OPG035":["S87L"]},"labels":{"aa":"OPG035: S87L"}}},{"name":"OR759199","node_attrs":{"div":7,"accession":"OR759199","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759199/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL111/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C135621T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179853T"]}}},{"name":"OR759184","node_attrs":{"div":7,"accession":"OR759184","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759184/2022-09-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL096/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G45236A","G132531A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR759147","node_attrs":{"div":7,"accession":"OR759147","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759147/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL057/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C923A","C26043T","G127179A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G196287T"],"OPG001":["G218V"],"OPG001_dup":["G218V"],"OPG042":["G352E"]},"labels":{"aa":"OPG001: G218V; OPG001_dup: G218V; OPG042: G352E"}}},{"name":"NODE_0000215","node_attrs":{"div":7,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C24282T","G28334A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG044":["E82K"]},"labels":{"aa":"OPG044: E82K"}},"children":[{"name":"OR759182","node_attrs":{"div":7,"accession":"OR759182","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759182/2022-09-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL094/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-196615A"]}}},{"name":"OR759181","node_attrs":{"div":8,"accession":"OR759181","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759181/2022-09-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL093/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C47672T"]}}}]},{"name":"NODE_0000216","node_attrs":{"div":7,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C13331T","G67225A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG085":["S436L"]},"labels":{"aa":"OPG085: S436L"}},"children":[{"name":"OR759189","node_attrs":{"div":7,"accession":"OR759189","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759189/2022-07-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-07-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL101/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000217","node_attrs":{"div":10,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G62952A","G100442A","G178818A"]}},"children":[{"name":"OR759223","node_attrs":{"div":16,"accession":"OR759223","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759223/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL135/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C1554T","C46542A","A87462T","A96625G","T96627C","T133948A","G195656A"],"OPG001":["A8T"],"OPG001_dup":["A8T"],"OPG109":["D662E"],"OPG117":["T193A"]},"labels":{"aa":"OPG001: A8T; OPG001_dup: A8T; OPG109: D662E; OPG117: T193A"}}},{"name":"OR759177","node_attrs":{"div":11,"accession":"OR759177","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759177/2022-09-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL089/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C181598T","-196615A"]}}},{"name":"OR759154","node_attrs":{"div":10,"accession":"OR759154","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759154/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1.4"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL063/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000218","node_attrs":{"div":1,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G74360A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG094":["R194H"]},"labels":{"aa":"OPG094: R194H","clade":"B.1.1"}},"children":[{"name":"OP184763","node_attrs":{"div":1,"accession":"OP184763","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OP184763/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.1"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-076773/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"]}}},{"name":"ON792321","node_attrs":{"div":1,"accession":"ON792321","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"strain_display":{"value":"Switzerland/ON792321/2022-06-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"date":{"value":"2022-06-02"},"lineage":{"value":"B.1.1"},"country":{"value":"Switzerland"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba6450e/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","A19360-","T19361-","C19362-","A19363-","T19364-","T19365-","A43653-","T43654-","T43655-","A49176-","A49177-","T49178-","T49179-","T49180-","T49181-","A49182-","T49183-","T49184-","A49185-","A49186-","C49187-","G49188-","G49189-","T49190-","A49191-","A49192-","T49193-","A79063-","A79064-","T79065-","T79066-","T79067-","T79068-","A79069-","A79070-","T79071-","A79072-","T79073-","A79074-","A79075-","T79076-","A79077-","C79078-","T79079-","T79080-","A79081-","A79082-","A79083-","A79084-","A79085-","T79086-","G79087-","G79088-","A79089-","T79090-","G79091-","T79092-","T79093-","G79094-","T79095-","G79096-","T79097-","C79098-","G79099-","T79100-","T79101-","A79102-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A152691-","A152692-","T152693-","G152694-","A152695-","C152696-","G152697-","T152698-","A175944-","T175945-","A175946-","T175947-","C175948-","A175949-","A175950-","C179127A","C179136T","T179138A","T179148-","T179157-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179190T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T180493-","A180494-","T180495-","C180496-","A180497-","T180498-","T180499-"],"OPG063":["D50-"],"OPG068":["N329-","G330-","N331-","T332-","F333-","I334-"],"OPG205":["I97-","S98-","I99-"]},"labels":{"aa":"OPG063: D50-; OPG068: N329-, G330-, N331-, T332-, F333-, I334-; OPG205: I97-, S98-, I99-"}}},{"name":"ON694329","node_attrs":{"div":1,"accession":"ON694329","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/ON694329/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI025"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A179185-","T179186-","A179187-","T179188-","A179189-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-","A192490-","A192491-","G192492-","T192493-","T192494-","A192495-","G192496-","T192497-","T192498-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP339846","node_attrs":{"div":3,"accession":"OP339846","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP339846/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI289"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C168264T","A179185-","T179186-","A179187-","T179188-","A179189-","G187135A"],"OPG195":["S12F"]},"labels":{"aa":"OPG195: S12F"}}},{"name":"OP382488","node_attrs":{"div":2,"accession":"OP382488","author":{"author":"Colson,P.","value":"Colson,P."},"strain_display":{"value":"France/OP382488/2022-07-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-19"},"lineage":{"value":"B.1.1"},"country":{"value":"France"},"strain":{"value":"hMPXV-IHU00011"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C153387T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP689676","node_attrs":{"div":1,"accession":"OP689676","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP689676/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI523"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A179185-","T179186-","A179187-","T179188-","A179189-"]}}},{"name":"OQ319132","node_attrs":{"div":1,"accession":"OQ319132","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ319132/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI674"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OQ547750","node_attrs":{"div":3,"accession":"OQ547750","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ547750/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI723"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G74176A","G150551-","T150564-","G150565-","A150566-","T150567-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","C187686T"],"OPG094":["D133N"]},"labels":{"aa":"OPG094: D133N"}}},{"name":"OR449632","node_attrs":{"div":1,"accession":"OR449632","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR449632/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI918"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"OR449635","node_attrs":{"div":2,"accession":"OR449635","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR449635/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI921"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G142240A","G150551-","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"OR264399","node_attrs":{"div":3,"accession":"OR264399","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264399/2022-06-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-06-30"},"lineage":{"value":"B.1.1"},"country":{"value":"Australia"},"strain":{"value":"36_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","A43500-","T76084-","T76085-","T80846-","T80847-","A89106-","G118500A","T121121-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G160406A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","C196772-","A196773-","T196774-"],"OPG044":["K147-"],"OPG136":["T363M"]},"labels":{"aa":"OPG044: K147-; OPG136: T363M"}}},{"name":"OR500080","node_attrs":{"div":10,"accession":"OR500080","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"strain_display":{"value":"Romania/OR500080/2022-08-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"date":{"value":"2022-08-16"},"lineage":{"value":"B.1.1"},"country":{"value":"Romania"},"strain":{"value":"hMpxV/Romania/B-18/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G17189T","A55140C","T55141A","T75369C","T91506G","G121663A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","T169776C","A173282G","A173284G","T174471A","G179029T","A179046T","A179081T","A179110T","T179121A","C179127T","T179129-","T179130-","T179139A","-179172A","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179190T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C179672A","C181209T"],"OPG073":["M1W"],"OPG074":["N662M"],"OPG208":["S136Y"]},"labels":{"aa":"OPG073: M1W; OPG074: N662M; OPG208: S136Y"}}},{"name":"OR500078","node_attrs":{"div":1,"accession":"OR500078","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"strain_display":{"value":"Romania/OR500078/2022-06-29"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"date":{"value":"2022-06-29"},"lineage":{"value":"B.1.1"},"country":{"value":"Romania"},"strain":{"value":"hMpxV/Romania/B-8/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T92388-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["F220-"]},"labels":{"aa":"OPG113: F220-"}}},{"name":"ON694333","node_attrs":{"div":1,"accession":"ON694333","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/ON694333/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A179185-","T179186-","A179187-","T179188-","A179189-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP382479","node_attrs":{"div":1,"accession":"OP382479","author":{"author":"Colson,P.","value":"Colson,P."},"strain_display":{"value":"France/OP382479/2022-07-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"date":{"value":"2022-07-01"},"lineage":{"value":"B.1.1"},"country":{"value":"France"},"strain":{"value":"hMPXV-IHU00002"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000220","node_attrs":{"div":2,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G173429A"]}},"children":[{"name":"ON694334","node_attrs":{"div":2,"accession":"ON694334","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/ON694334/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI021"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A179185-","T179186-","A179187-","T179188-","A179189-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP204857","node_attrs":{"div":3,"accession":"OP204857","author":{"author":"Rhie,G.-E.","value":"Rhie,G.-E."},"strain_display":{"value":"South Korea/OP204857/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.1"},"country":{"value":"South Korea"},"strain":{"value":"MPXV-ROK-P1-2022"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C786T","C71728T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG091":["A120V"]},"labels":{"aa":"OPG091: A120V"}}}]},{"name":"NODE_0000221","node_attrs":{"div":2,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C22739T","A179185-","T179186-","A179187-","T179188-","A179189-"],"OPG038":["E141K"]},"labels":{"aa":"OPG038: E141K"}},"children":[{"name":"OP019276","node_attrs":{"div":2,"accession":"OP019276","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"strain_display":{"value":"Austria/OP019276/2022-06-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"date":{"value":"2022-06-21"},"lineage":{"value":"B.1.1"},"country":{"value":"Austria"},"strain":{"value":"hMPXV/Austria/MUW1527495/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON694331","node_attrs":{"div":2,"accession":"ON694331","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/ON694331/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI015"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP215267","node_attrs":{"div":4,"accession":"OP215267","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP215267/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI247"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C186124T","C189996T"],"OPG210":["S1590F"]},"labels":{"aa":"OPG210: S1590F"}}},{"name":"NODE_0000222","node_attrs":{"div":4,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G55993A","G173727A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG074":["S378F"]},"labels":{"aa":"OPG074: S378F"}},"children":[{"name":"OP355578","node_attrs":{"div":4,"accession":"OP355578","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP355578/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI322"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","G179263-","C179264-","C179265-","A179266-","T179267-","A188351-"]}}},{"name":"OQ547775","node_attrs":{"div":5,"accession":"OQ547775","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ547775/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI748"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C129096T","G150551-","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG151":["S58L"]},"labels":{"aa":"OPG151: S58L"}}}]}]},{"name":"NODE_0000223","node_attrs":{"div":2,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G155698A"]}},"children":[{"name":"OP555659","node_attrs":{"div":7,"accession":"OP555659","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555659/2022-09-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-14"},"lineage":{"value":"B.1.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0592/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G685-","T686-","C21910T","C67207T","G81244A","G109451A","G138237A","A179185-","T179186-","A179187-","T179188-","A179189-","-196615A"],"OPG037":["R175K"],"OPG085":["R442K"],"OPG105":["R40K"]},"labels":{"aa":"OPG037: R175K; OPG085: R442K; OPG105: R40K"}}},{"name":"OR086989","node_attrs":{"div":5,"accession":"OR086989","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR086989/2022-07-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-27"},"lineage":{"value":"B.1.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_180/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C7037T","G10930A","C109896T","T133102-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG129":["R370K"]},"labels":{"aa":"OPG129: R370K"}}},{"name":"NODE_0000224","node_attrs":{"div":3,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G161575A"]}},"children":[{"name":"OP555473","node_attrs":{"div":3,"accession":"OP555473","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555473/2022-07-06"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-07-06"},"lineage":{"value":"B.1.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0377/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","A179185-","T179186-","A179187-","T179188-","A179189-"]}}},{"name":"OR459775","node_attrs":{"div":5,"accession":"OR459775","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain_display":{"value":"South Korea/OR459775/2022-09-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2022-09-02"},"lineage":{"value":"B.1.1"},"country":{"value":"South Korea"},"strain":{"value":"MPXV-ROK-P002-2022"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G14640A","C108843T","G136558C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG025":["H210Y"],"OPG153":["I370M"]},"labels":{"aa":"OPG025: H210Y; OPG153: I370M"}}},{"name":"OR086942","node_attrs":{"div":3,"accession":"OR086942","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR086942/2022-07-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1.1"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_133/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133102-","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196748-","T196749-","C196750-"]}}}]}]},{"name":"NODE_0000225","node_attrs":{"div":6,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C46672T","C56805T","C72314T","C103216T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","T152686-","A169769-","C169770-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C180857T"],"OPG066":["E253K"],"OPG074":["M107I"],"OPG092":["D212N"],"OPG123":["V619I"]},"labels":{"aa":"OPG066: E253K; OPG074: M107I; OPG092: D212N; OPG123: V619I"}},"children":[{"name":"OR500082","node_attrs":{"div":6,"accession":"OR500082","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"strain_display":{"value":"Romania/OR500082/2023-01-26"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"date":{"value":"2023-01-26"},"lineage":{"value":"B.1.1"},"country":{"value":"Romania"},"strain":{"value":"hMpxV/Romania/B-35_L2/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A169771-","G169772-","A169773-","T169774-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"OR500083","node_attrs":{"div":8,"accession":"OR500083","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"strain_display":{"value":"Romania/OR500083/2023-02-15"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"date":{"value":"2023-02-15"},"lineage":{"value":"B.1.1"},"country":{"value":"Romania"},"strain":{"value":"hMpxV/Romania/B-35_L3/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C9781T","G127563A","-169769A","-169770C"],"OPG149":["R123Q"]},"labels":{"aa":"OPG149: R123Q"}}},{"name":"NODE_0000226","node_attrs":{"div":7,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C127628T"],"OPG149":["P145S"]},"labels":{"aa":"OPG149: P145S"}},"children":[{"name":"OR500081","node_attrs":{"div":8,"accession":"OR500081","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"strain_display":{"value":"Romania/OR500081/2023-01-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"date":{"value":"2023-01-05"},"lineage":{"value":"B.1.1"},"country":{"value":"Romania"},"strain":{"value":"hMpxV/Romania/B-35_L1/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C16327T"]}}},{"name":"NODE_0000227","node_attrs":{"div":8,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C42674T"],"OPG063":["E339K"]},"labels":{"aa":"OPG063: E339K"}},"children":[{"name":"OR500086","node_attrs":{"div":10,"accession":"OR500086","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"strain_display":{"value":"Romania/OR500086/2023-02-15"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"date":{"value":"2023-02-15"},"lineage":{"value":"B.1.1"},"country":{"value":"Romania"},"strain":{"value":"hMpxV/Romania/B-35_R3/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G169748A","C179190T","T179192A","T179193A","A179198G","C179199-","A179200-","T179201-","A185438C","C185439A"]}}},{"name":"OR500085","node_attrs":{"div":8,"accession":"OR500085","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"strain_display":{"value":"Romania/OR500085/2023-01-26"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"date":{"value":"2023-01-26"},"lineage":{"value":"B.1.1"},"country":{"value":"Romania"},"strain":{"value":"hMpxV/Romania/B-35_R2/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-169769A","-169770C"]}}},{"name":"OR500084","node_attrs":{"div":8,"accession":"OR500084","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"strain_display":{"value":"Romania/OR500084/2023-01-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"date":{"value":"2023-01-05"},"lineage":{"value":"B.1.1"},"country":{"value":"Romania"},"strain":{"value":"hMpxV/Romania/B-35_R1/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A169771-","G169772-","A169773-","T169774-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}}]}]}]},{"name":"NODE_0000228","node_attrs":{"div":2,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","C29887T","T76084-","T76085-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG044":["K147-"]},"labels":{"aa":"OPG044: K147-"}},"children":[{"name":"OR264454","node_attrs":{"div":2,"accession":"OR264454","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264454/2022-08-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-25"},"lineage":{"value":"B.1.1"},"country":{"value":"Australia"},"strain":{"value":"67_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-28529A","-28530A","T170904-","-179229T","T179244-","C179245-","G179246-","T179247-"],"OPG044":["-147K"]},"labels":{"aa":"OPG044: -147K"}}},{"name":"OR264437","node_attrs":{"div":2,"accession":"OR264437","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264437/2022-09-06"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-09-06"},"lineage":{"value":"B.1.1"},"country":{"value":"Australia"},"strain":{"value":"56_C"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-76084T","-76085T"]}}},{"name":"OR264438","node_attrs":{"div":3,"accession":"OR264438","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264438/2022-09-06"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-09-06"},"lineage":{"value":"B.1.1"},"country":{"value":"Australia"},"strain":{"value":"56_D"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C89382T"]}}},{"name":"OR264439","node_attrs":{"div":2,"accession":"OR264439","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264439/2022-09-06"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-09-06"},"lineage":{"value":"B.1.1"},"country":{"value":"Australia"},"strain":{"value":"56_F"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-76084T","-76085T"]}}},{"name":"OR264410","node_attrs":{"div":2,"accession":"OR264410","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264410/2022-07-29"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-07-29"},"lineage":{"value":"B.1.1"},"country":{"value":"Australia"},"strain":{"value":"3_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-28529A","-28530A","-76084T","-76085T","-196615A"],"OPG044":["-147K"]},"labels":{"aa":"OPG044: -147K"}}},{"name":"OR264372","node_attrs":{"div":2,"accession":"OR264372","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264372/2022-08-24"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-24"},"lineage":{"value":"B.1.1"},"country":{"value":"Australia"},"strain":{"value":"19_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T80846-","T80847-","A89106-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A152675-","A152676-","A165461-"],"OPG190":["N114-"]},"labels":{"aa":"OPG190: N114-"}}},{"name":"OR264371","node_attrs":{"div":2,"accession":"OR264371","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264371/2022-08-24"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-24"},"lineage":{"value":"B.1.1"},"country":{"value":"Australia"},"strain":{"value":"19_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-28529A","-28530A"],"OPG044":["-147K"]},"labels":{"aa":"OPG044: -147K"}}}]}]},{"name":"NODE_0000229","node_attrs":{"div":1,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C25644T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]},"labels":{"clade":"B.1.7"}},"children":[{"name":"OP225963","node_attrs":{"div":2,"accession":"OP225963","author":{"author":"Gigante,C.M.,Steidley,B.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Davizon,E.,Li,Y.","value":"Gigante,C.M.,Steidley,B.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Davizon,E.,Li,Y."},"strain_display":{"value":"USA/OP225963/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_CO0006"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C186970T"],"OPG210":["S1872F"]},"labels":{"aa":"OPG210: S1872F"}}},{"name":"OP205119","node_attrs":{"div":4,"accession":"OP205119","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205119/2022-07-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000161"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G23359A","C114955T","C116175T","-179172C","-179173A","-179174T","-179175T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG039":["L254F"],"OPG133":["D248N"]},"labels":{"aa":"OPG039: L254F; OPG133: D248N"}}},{"name":"OP205103","node_attrs":{"div":2,"accession":"OP205103","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205103/2022-07-06"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-06"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000138"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C12842T","-179172C","-179173A","-179174T","-179175T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG023":["R20K"]},"labels":{"aa":"OPG023: R20K"}}},{"name":"OP205081","node_attrs":{"div":1,"accession":"OP205081","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205081/2022-06-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-14"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000078"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP536814","node_attrs":{"div":2,"accession":"OP536814","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536814/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"9000452"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A57256G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP536774","node_attrs":{"div":3,"accession":"OP536774","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536774/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"9000396"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G50034A","G74200A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG069":["E17K"],"OPG094":["D141N"]},"labels":{"aa":"OPG069: E17K; OPG094: D141N"}}},{"name":"OP597782","node_attrs":{"div":4,"accession":"OP597782","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"strain_display":{"value":"USA/OP597782/2022-07-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"Minnesota Department of Health"},"date":{"value":"2022-07-05"},"lineage":{"value":"B.1.7"},"country":{"value":"USA"},"strain":{"value":"MN-MDH-MPXV_0008"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G74619A","G83118A","T87356C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"],"OPG105":["A665T"],"OPG109":["K698E"]},"labels":{"aa":"OPG105: A665T; OPG109: K698E"}}},{"name":"OQ159037","node_attrs":{"div":5,"accession":"OQ159037","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ159037/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI642"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C66249T","C88644A","C104134T","C112638T","-179194A","-179195T","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG109":["K268N"],"OPG123":["A313T"]},"labels":{"aa":"OPG109: K268N; OPG123: A313T"}}},{"name":"OR759218","node_attrs":{"div":3,"accession":"OR759218","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759218/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1.7"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL130/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C81095T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C172410T","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"]}}},{"name":"NODE_0000230","node_attrs":{"div":4,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T611-","A612-","G114316A","C148771T","G152437A","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-"],"OPG133":["H461Y"],"OPG174":["D209N"]},"labels":{"aa":"OPG133: H461Y; OPG174: D209N"}},"children":[{"name":"OQ159026","node_attrs":{"div":5,"accession":"OQ159026","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ159026/2022-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI631"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-611T","-612A","G150547A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","G187677A"]}}},{"name":"OQ627928","node_attrs":{"div":4,"accession":"OQ627928","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"strain_display":{"value":"Italy/OQ627928/2022-09-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"date":{"value":"2022-09-14"},"lineage":{"value":"B.1.7"},"country":{"value":"Italy"},"strain":{"value":"INMI-19442022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-608T","G610-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}}]},{"name":"NODE_0000231","node_attrs":{"div":2,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G63147A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"]}},"children":[{"name":"OP263633","node_attrs":{"div":3,"accession":"OP263633","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP263633/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI278"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G157546A"]}}},{"name":"OP536776","node_attrs":{"div":4,"accession":"OP536776","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536776/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"9000398"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C157854T","C164272T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A190779-","C190780-","T190781-","G190782-","A190783-","A190784-","A190785-","T190786-","T190787-"],"OPG016":["T124-","E125-","I126-"],"OPG189":["R314C"]},"labels":{"aa":"OPG016: T124-, E125-, I126-; OPG189: R314C"}}},{"name":"NODE_0000232","node_attrs":{"div":6,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G10224A","G129761A","T143625A","C177847T","-196615A"],"OPG021":["R213Q"],"OPG151":["D280N"],"OPG165":["I37N"],"OPG205":["S731L"]},"labels":{"aa":"OPG021: R213Q; OPG151: D280N; OPG165: I37N; OPG205: S731L"}},"children":[{"name":"ON927248","node_attrs":{"div":6,"accession":"ON927248","author":{"author":"Chan,W.Y.,Mtshali,P.S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J.","value":"Chan,W.Y.,Mtshali,P.S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J."},"strain_display":{"value":"South Africa/ON927248/2022-06-24"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute for Communicable Disease, Sequencing core facility"},"date":{"value":"2022-06-24"},"lineage":{"value":"B.1.7"},"country":{"value":"South Africa"},"strain":{"value":"NICD-SVPL232"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A196601C"]}}},{"name":"ON918611","node_attrs":{"div":6,"accession":"ON918611","author":{"author":"Chan,W.Y.,Mtshali,S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J.","value":"Chan,W.Y.,Mtshali,S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J."},"strain_display":{"value":"South Africa/ON918611/2022-06-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute for Communicable Disease, Sequencing Core Facility"},"date":{"value":"2022-06-20"},"lineage":{"value":"B.1.7"},"country":{"value":"South Africa"},"strain":{"value":"NICD-SVPL223"},"region":{"value":"Africa"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T"]}}}]}]},{"name":"NODE_0000233","node_attrs":{"div":2,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G180608A"],"OPG209":["E31K"]},"labels":{"aa":"OPG209: E31K"}},"children":[{"name":"OP536801","node_attrs":{"div":3,"accession":"OP536801","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536801/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"9000429"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G160946A","T190787-"],"OPG187":["D109N"]},"labels":{"aa":"OPG187: D109N"}}},{"name":"OP536777","node_attrs":{"div":2,"accession":"OP536777","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536777/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"9000399"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP536775","node_attrs":{"div":2,"accession":"OP536775","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536775/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"9000397"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-196615A"]}}},{"name":"OP727822","node_attrs":{"div":9,"accession":"OP727822","author":{"author":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K.","value":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K."},"strain_display":{"value":"Belgium/OP727822/2022-10-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-10-02"},"lineage":{"value":"B.1.7"},"country":{"value":"Belgium"},"strain":{"value":"PrEV_case_2"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T604-","T605-","T606-","C11401T","C33964T","C36267T","C57173T","G110285A","T133102-","C144366T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A174924T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A188351-","G195316A"],"OPG052":["R11Q"],"OPG055":["D273N"]},"labels":{"aa":"OPG052: R11Q; OPG055: D273N"}}}]},{"name":"NODE_0000234","node_attrs":{"div":2,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G120241A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"],"OPG137":["D214N"]},"labels":{"aa":"OPG137: D214N"}},"children":[{"name":"ON911481","node_attrs":{"div":5,"accession":"ON911481","author":{"author":"Galan-Huerta,K.A.,Paz-Infanzon,M.,Ruiz-Higareda,A.F.,Nuzzolo-Shihadeh,L.,Camacho-Ortiz,A.,Bocanegra-Ibarias,P.,Rivas-Estilla,A.M.,Zacarias-Villarreal,D.,Yamallel-Ortega,L.A.,Guerrero-Putz,M.D.,Ocampo-Candiani,J.","value":"Galan-Huerta,K.A.,Paz-Infanzon,M.,Ruiz-Higareda,A.F.,Nuzzolo-Shihadeh,L.,Camacho-Ortiz,A.,Bocanegra-Ibarias,P.,Rivas-Estilla,A.M.,Zacarias-Villarreal,D.,Yamallel-Ortega,L.A.,Guerrero-Putz,M.D.,Ocampo-Candiani,J."},"strain_display":{"value":"Mexico/ON911481/2022-06-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"Universidad Autonoma de Nuevo Leon - Facultad de Medicina, Centro de Investigacion e Innovacion en Virologia Medica"},"date":{"value":"2022-06-28"},"lineage":{"value":"B.1.7"},"country":{"value":"Mexico"},"strain":{"value":"Monkeypox/MX-UANL001/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G57088A","C127530T","T133098-","T133099-","T133100-","T133101-","T133102-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","T168120C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG074":["S13L"],"OPG149":["S112L"],"OPG193":["F263L"]},"labels":{"aa":"OPG074: S13L; OPG149: S112L; OPG193: F263L"}}},{"name":"OP215210","node_attrs":{"div":2,"accession":"OP215210","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP215210/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI202"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP484678","node_attrs":{"div":2,"accession":"OP484678","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP484678/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI357"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP484682","node_attrs":{"div":4,"accession":"OP484682","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP484682/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI361"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C168226T","C175467T"]}}},{"name":"OP603017","node_attrs":{"div":3,"accession":"OP603017","author":{"author":"Gigante,C.M.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y.","value":"Gigante,C.M.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y."},"strain_display":{"value":"USA/OP603017/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_CA0033"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","T133098-","T133099-","T133100-","T133101-","T133102-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C161008T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}}]},{"name":"NODE_0000235","node_attrs":{"div":2,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G42504A","-179172C","-179173A","-179174T","-179175T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP205111","node_attrs":{"div":3,"accession":"OP205111","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205111/2022-06-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-14"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000148"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C15562T"]}}},{"name":"OP205076","node_attrs":{"div":2,"accession":"OP205076","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205076/2022-06-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-09"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000070"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP204840","node_attrs":{"div":3,"accession":"OP204840","author":{"author":"Seang,S.,Burrel,S.,Todesco,E.,Leducq,V.,Monsel,G.,Le Pluart,D.,Cordevant,C.,Pourcher,V.,Palich,R.,Charpentier,C.","value":"Seang,S.,Burrel,S.,Todesco,E.,Leducq,V.,Monsel,G.,Le Pluart,D.,Cordevant,C.,Pourcher,V.,Palich,R.,Charpentier,C."},"strain_display":{"value":"France/OP204840/2022-06-10"},"host":{"value":"Homo sapiens"},"institution":{"value":"APHP Pitie Salpetriere SU, Virology"},"date":{"value":"2022-06-10"},"lineage":{"value":"B.1.7"},"country":{"value":"France"},"strain":{"value":"PatientMPXV"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G163250A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196612-","A196613-","A196614-"]}}},{"name":"OP415190","node_attrs":{"div":5,"accession":"OP415190","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415190/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_KJ3uDD_9000210"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C36834T","G168034A","C181209T","A181253-"],"OPG055":["E84K"],"OPG193":["R234K"]},"labels":{"aa":"OPG055: E84K; OPG193: R234K"}}},{"name":"NODE_0000236","node_attrs":{"div":3,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C115870T"]}},"children":[{"name":"OP415218","node_attrs":{"div":5,"accession":"OP415218","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415218/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_V5dRAI_9000247"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C30137T","C52231T"],"OPG047":["R353K"]},"labels":{"aa":"OPG047: R353K"}}},{"name":"OP414310","node_attrs":{"div":6,"accession":"OP414310","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP414310/2022-06-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-06-16"},"lineage":{"value":"B.1.7"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0270/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C5292T","G74267A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A161784T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G191918A"],"OPG015":["D289N"],"OPG015_dup":["D289N"],"OPG094":["R163Q"]},"labels":{"aa":"OPG015: D289N; OPG015_dup: D289N; OPG094: R163Q"}}}]}]},{"name":"NODE_0000237","node_attrs":{"div":2,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C14077T","-179172C","-179173A","-179174T","-179175T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP205084","node_attrs":{"div":4,"accession":"OP205084","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205084/2022-05-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-05-30"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000093"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C4529T","G155585A","G192681A"],"OPG003":["D27N"],"OPG003_dup":["D27N"]},"labels":{"aa":"OPG003: D27N; OPG003_dup: D27N"}}},{"name":"OP205077","node_attrs":{"div":2,"accession":"OP205077","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205077/2022-06-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-09"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000071"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000238","node_attrs":{"div":3,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G147799A"],"OPG172":["A125T"]},"labels":{"aa":"OPG172: A125T"}},"children":[{"name":"OP415222","node_attrs":{"div":5,"accession":"OP415222","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415222/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_12DvO8_9000251"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G27260A","G46325A"]}}},{"name":"OP415201","node_attrs":{"div":3,"accession":"OP415201","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415201/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_K1dQNt_9000225"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000239","node_attrs":{"div":3,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G105860A"]}},"children":[{"name":"OP415198","node_attrs":{"div":5,"accession":"OP415198","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415198/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_2v76E1_9000222"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G41557A","G91376A"],"OPG061":["P110S"],"OPG112":["D44N"]},"labels":{"aa":"OPG061: P110S; OPG112: D44N"}}},{"name":"OR095063","node_attrs":{"div":3,"accession":"OR095063","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR095063/2022-08-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-08-16"},"lineage":{"value":"B.1.7"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_245/Belgium/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}}]}]},{"name":"NODE_0000240","node_attrs":{"div":3,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C57173T","C142797T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG164":["S7L"]},"labels":{"aa":"OPG164: S7L"}},"children":[{"name":"OP536783","node_attrs":{"div":7,"accession":"OP536783","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536783/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.7"},"country":{"value":"United Kingdom"},"strain":{"value":"9000407"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C9610T","G15029A","G41336A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G180889A","T190787-"],"OPG025":["S80F"]},"labels":{"aa":"OPG025: S80F"}}},{"name":"OP480419","node_attrs":{"div":8,"accession":"OP480419","author":{"author":"Deanhardt,B.,Miller,M.,Wang,J.R.","value":"Deanhardt,B.,Miller,M.,Wang,J.R."},"strain_display":{"value":"USA/OP480419/2022-08-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"University of North Carolina at Chapel Hill, Department of Genetics"},"date":{"value":"2022-08-30"},"lineage":{"value":"B.1.7"},"country":{"value":"USA"},"strain":{"value":"hMPXV/USA/NC-UNC-0020/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C23868T","A31053G","C128717T","G143512A","C173533A","-179172C","-179173A","-179174T","-179175T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG039":["G84E"],"OPG047":["C48R"]},"labels":{"aa":"OPG039: G84E; OPG047: C48R"}}},{"name":"OQ918697","node_attrs":{"div":11,"accession":"OQ918697","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ918697/2023-02-18"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-02-18"},"lineage":{"value":"B.1.7"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00486/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C55036T","G73789A","C96914T","C136435T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G158254A","C166803T","C170381T","G178559A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG073":["E36K"],"OPG094":["G4R"],"OPG117":["S289L"],"OPG192":["P25S"],"OPG198":["S115L"]},"labels":{"aa":"OPG073: E36K; OPG094: G4R; OPG117: S289L; OPG192: P25S; OPG198: S115L"}}},{"name":"OR264396","node_attrs":{"div":8,"accession":"OR264396","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264396/2022-09-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-09-07"},"lineage":{"value":"B.1.7"},"country":{"value":"Australia"},"strain":{"value":"33_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G14622A","A28529-","A28530-","T76084-","T76085-","G101241A","T133102-","C136244T","C156446T","G174708A"],"OPG025":["R216C"],"OPG044":["K147-"],"OPG153":["R475K"],"OPG204":["M59I"]},"labels":{"aa":"OPG025: R216C; OPG044: K147-; OPG153: R475K; OPG204: M59I"}}},{"name":"NODE_0000241","node_attrs":{"div":6,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C30137T","C55072T","G130068A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"],"OPG047":["R353K"],"OPG073":["D24N"],"OPG151":["R382Q"]},"labels":{"aa":"OPG047: R353K; OPG073: D24N; OPG151: R382Q"}},"children":[{"name":"OR759178","node_attrs":{"div":7,"accession":"OR759178","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759178/2022-09-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1.7"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL090/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G26352A","A196614-"],"OPG042":["A249V"]},"labels":{"aa":"OPG042: A249V"}}},{"name":"OR759165","node_attrs":{"div":6,"accession":"OR759165","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759165/2022-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-08-01"},"lineage":{"value":"B.1.7"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL077/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000242","node_attrs":{"div":1,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N","clade":"B.1.2"}},"children":[{"name":"OP150927","node_attrs":{"div":1,"accession":"OP150927","author":{"author":"Gigante,C.,Pavlick,J.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y.","value":"Gigante,C.,Pavlick,J.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y."},"strain_display":{"value":"USA/OP150927/2022-05-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-05-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_WA001"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON929079","node_attrs":{"div":1,"accession":"ON929079","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/ON929079/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI124"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"]}}},{"name":"OP415204","node_attrs":{"div":1,"accession":"OP415204","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415204/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_fZLVcc_9000229"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP594186","node_attrs":{"div":2,"accession":"OP594186","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP594186/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI422"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G832A","G94840A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","C196378T"],"OPG115":["E61K"]},"labels":{"aa":"OPG115: E61K"}}},{"name":"OR449712","node_attrs":{"div":2,"accession":"OR449712","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR449712/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/ON/RKI998"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C40648T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"NODE_0000243","node_attrs":{"div":2,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G143789A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG165":["D92N"]},"labels":{"aa":"OPG165: D92N"}},"children":[{"name":"OP415250","node_attrs":{"div":6,"accession":"OP415250","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415250/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_xSF5DR_9000295"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G20678-","G69081A","C87817T","G141543A","G161483A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG109":["G544E"],"OPG161":["V148I"],"OPG187":["D288N"]},"labels":{"aa":"OPG109: G544E; OPG161: V148I; OPG187: D288N"}}},{"name":"NODE_0000244","node_attrs":{"div":3,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C20992T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG036":["D25N"]},"labels":{"aa":"OPG036: D25N"}},"children":[{"name":"OP536768","node_attrs":{"div":5,"accession":"OP536768","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536768/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"United Kingdom"},"strain":{"value":"9000390"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C29229T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G165371A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG045":["D12N"],"OPG190":["E84K"]},"labels":{"aa":"OPG045: D12N; OPG190: E84K"}}},{"name":"NODE_0000245","node_attrs":{"div":4,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C147168T"],"OPG171":["L61F"]},"labels":{"aa":"OPG171: L61F"}},"children":[{"name":"OR264413","node_attrs":{"div":4,"accession":"OR264413","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264413/2022-06-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-06-22"},"lineage":{"value":"B.1.2"},"country":{"value":"Australia"},"strain":{"value":"42_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR264412","node_attrs":{"div":4,"accession":"OR264412","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264412/2022-06-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-06-08"},"lineage":{"value":"B.1.2"},"country":{"value":"Australia"},"strain":{"value":"42_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C133103T","G133104-","A133105-","A133106-","A133201-","C133202-","C133203-","T133204-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","T196669-","T196670-","T196671-"]}}},{"name":"OR264416","node_attrs":{"div":4,"accession":"OR264416","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264416/2022-06-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-06-22"},"lineage":{"value":"B.1.2"},"country":{"value":"Australia"},"strain":{"value":"42_G"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR264414","node_attrs":{"div":4,"accession":"OR264414","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264414/2022-06-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-06-22"},"lineage":{"value":"B.1.2"},"country":{"value":"Australia"},"strain":{"value":"42_C"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP215208","node_attrs":{"div":4,"accession":"OP215208","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP215208/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI196"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"]}}},{"name":"OR264415","node_attrs":{"div":4,"accession":"OR264415","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264415/2022-06-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-06-22"},"lineage":{"value":"B.1.2"},"country":{"value":"Australia"},"strain":{"value":"42_F"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000249","node_attrs":{"div":2,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179191A","-179192T","-179193T","C188391T"]}},"children":[{"name":"OP205086","node_attrs":{"div":2,"accession":"OP205086","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205086/2022-06-06"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-06-06"},"lineage":{"value":"B.1.2"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000097"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP205083","node_attrs":{"div":2,"accession":"OP205083","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205083/2022-05-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-05-25"},"lineage":{"value":"B.1.2"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000092"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP539916","node_attrs":{"div":2,"accession":"OP539916","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OP539916/2022-09-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-09-09"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00131/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-"]}}},{"name":"OP539914","node_attrs":{"div":2,"accession":"OP539914","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OP539914/2022-09-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-09-09"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00129/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","T179244-"]}}},{"name":"OP536784","node_attrs":{"div":2,"accession":"OP536784","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536784/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"United Kingdom"},"strain":{"value":"9000408"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ348860","node_attrs":{"div":11,"accession":"OQ348860","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"strain_display":{"value":"USA/OQ348860/2022-12-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2022-12-14"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000112/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C7705T","C39334G","G50617A","G62896A","G89947A","C110394T","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G150753A","A158920T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G183899A"],"OPG057":["A288P"],"OPG070":["D10N"],"OPG082":["S186L"],"OPG110":["E106K"],"OPG129":["R204Q"],"OPG185":["T2S"]},"labels":{"aa":"OPG057: A288P; OPG070: D10N; OPG082: S186L; OPG110: E106K; OPG129: R204Q; OPG185: T2S"}}},{"name":"OQ330994","node_attrs":{"div":5,"accession":"OQ330994","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ330994/2022-10-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-10-25"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00386/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G70089A","G137585A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G175165A","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","T179244-"],"OPG089":["R75K"],"OPG153":["S28F"],"OPG204":["E212K"]},"labels":{"aa":"OPG089: R75K; OPG153: S28F; OPG204: E212K"}}},{"name":"OQ557955","node_attrs":{"div":4,"accession":"OQ557955","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"strain_display":{"value":"USA/OQ557955/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_TX0008"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G118640A","C120279T","-179194A","-179195T","-179196A","-179197T","-179198A"]}}},{"name":"OQ557954","node_attrs":{"div":6,"accession":"OQ557954","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"strain_display":{"value":"USA/OQ557954/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_TX0006"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G25309A","G103413A","G133968T","G157666A","C179190-","A179191-","T179192-","T179193-"],"OPG040":["S57L"],"OPG123":["S553F"]},"labels":{"aa":"OPG040: S57L; OPG123: S553F"}}},{"name":"OQ721945","node_attrs":{"div":5,"accession":"OQ721945","author":{"author":"Gigante,C.,Segaloff,H.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Florek,K.,Li,Y.","value":"Gigante,C.,Segaloff,H.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Florek,K.,Li,Y."},"strain_display":{"value":"USA/OQ721945/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_WI0004"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C27730T","T39315A","C58502T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-"],"OPG043":["D76N"],"OPG057":["D294V"],"OPG077":["E28K"]},"labels":{"aa":"OPG043: D76N; OPG057: D294V; OPG077: E28K"}}},{"name":"OQ626771","node_attrs":{"div":3,"accession":"OQ626771","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"strain_display":{"value":"USA/OQ626771/2022-10-04"},"host":{"value":"Homo sapiens"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"date":{"value":"2022-10-04"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MPXV22/human/USA-NE-331"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G30768A","G150603-","A150604-","T150605-","A150606-","T150607-","G150608-","A150609-","T150610-","G150611-","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG047":["H143Y"]},"labels":{"aa":"OPG047: H143Y"}}},{"name":"OR209314","node_attrs":{"div":3,"accession":"OR209314","author":{"author":"Li,C.M.","value":"Li,C.M."},"strain_display":{"value":"USA/OR209314/2022-11-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-11-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_IN0004"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G137594A","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG153":["A25V"]},"labels":{"aa":"OPG153: A25V"}}},{"name":"NODE_0000250","node_attrs":{"div":5,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C17614A","G147305A","C159401A","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG030":["V74L"],"OPG185":["S162Y"]},"labels":{"aa":"OPG030: V74L; OPG185: S162Y"}},"children":[{"name":"OP415234","node_attrs":{"div":11,"accession":"OP415234","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415234/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_L6rBi6_9000265"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C102961T","G125022A","G148467A","G159243A","C171808T","G177398A"],"OPG145":["R359K"],"OPG174":["T310I"],"OPG199":["S274L"]},"labels":{"aa":"OPG145: R359K; OPG174: T310I; OPG199: S274L"}}},{"name":"OP605583","node_attrs":{"div":7,"accession":"OP605583","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605583/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-42-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A161-","-607T","C27187T","G111484A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG043":["D257N"],"OPG130":["T140I"]},"labels":{"aa":"OPG043: D257N; OPG130: T140I"}}}]},{"name":"NODE_0000251","node_attrs":{"div":11,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T11371C","G34303A","C85322T","G92048A","G123119A","G129583A","C140931T","C153104T","C178378T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG053":["P130S"],"OPG143":["S66L"],"OPG180":["S138F"]},"labels":{"aa":"OPG053: P130S; OPG143: S66L; OPG180: S138F"}},"children":[{"name":"OP415205","node_attrs":{"div":11,"accession":"OP415205","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP415205/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"United Kingdom"},"strain":{"value":"MPX_TcUINH_9000230"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP413713","node_attrs":{"div":11,"accession":"OP413713","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP413713/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"United Kingdom"},"strain":{"value":"9000231"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000252","node_attrs":{"div":6,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T26669C","G96073A","G115235A","C125294T"],"OPG117":["D9N"]},"labels":{"aa":"OPG117: D9N"}},"children":[{"name":"OQ159027","node_attrs":{"div":8,"accession":"OQ159027","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ159027/2022-11-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-11-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI632"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G77052A","C135868T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-"]}}},{"name":"OP959060","node_attrs":{"div":6,"accession":"OP959060","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"strain_display":{"value":"Colombia/OP959060/2022-10-29"},"host":{"value":"Homo sapiens"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"date":{"value":"2022-10-29"},"lineage":{"value":"B.1.2"},"country":{"value":"Colombia"},"strain":{"value":"BOL-UNIMOL-MPX-293428-L"},"region":{"value":"South America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000253","node_attrs":{"div":3,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G45781A"],"OPG064":["H40Y"]},"labels":{"aa":"OPG064: H40Y"}},"children":[{"name":"OP890537","node_attrs":{"div":10,"accession":"OP890537","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OP890537/2022-09-29"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2022-09-29"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00303/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G10546A","G23873A","G67898A","C100640T","G133763A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C169975T","C177917T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A196614-"],"OPG022":["H105Y"],"OPG085":["P212S"]},"labels":{"aa":"OPG022: H105Y; OPG085: P212S"}}},{"name":"OQ503746","node_attrs":{"div":8,"accession":"OQ503746","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OQ503746/2022-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-108047/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G24471A","C25882T","G71465A","G171761A","C177099T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG042":["D406N"],"OPG205":["R482*"]},"labels":{"aa":"OPG042: D406N; OPG205: R482*"}}}]},{"name":"NODE_0000254","node_attrs":{"div":6,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G2126A","C64132T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C154736T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","G183791A","C195084T"],"OPG002":["S209L"],"OPG002_dup":["S209L"],"OPG083":["M195I"],"OPG181":["P109S"]},"labels":{"aa":"OPG002: S209L; OPG002_dup: S209L; OPG083: M195I; OPG181: P109S"}},"children":[{"name":"OR178739","node_attrs":{"div":8,"accession":"OR178739","author":{"author":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J.","value":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J."},"strain_display":{"value":"USA/OR178739/2023-01-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2023-01-12"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000172/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T748-","G749-","C750-","G39327A","C110699T"],"OPG057":["A290V"]},"labels":{"aa":"OPG057: A290V"}}},{"name":"NODE_0000255","node_attrs":{"div":13,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A670-","A671-","G10224A","T39348C","A78942G","T130733C","G138728A","A155151C","T187664C","T196774-","A196775-","A196776-"],"OPG021":["R213Q"],"OPG057":["D283G"],"OPG101":["T153A"],"OPG151":["C604R"],"OPG156":["H228Y"],"OPG181":["E247A"]},"labels":{"aa":"OPG021: R213Q; OPG057: D283G; OPG101: T153A; OPG151: C604R; OPG156: H228Y; OPG181: E247A"}},"children":[{"name":"OR178742","node_attrs":{"div":13,"accession":"OR178742","author":{"author":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J.","value":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J."},"strain_display":{"value":"USA/OR178742/2023-02-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2023-02-14"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000194/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G669-"]}}},{"name":"OR178741","node_attrs":{"div":14,"accession":"OR178741","author":{"author":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J.","value":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J."},"strain_display":{"value":"USA/OR178741/2023-02-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDPH, VRDL"},"date":{"value":"2023-02-14"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000193/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-670A","-671A","A31053G","-196774T","-196775A","-196776A"],"OPG047":["C48R"]},"labels":{"aa":"OPG047: C48R"}}}]}]},{"name":"NODE_0000256","node_attrs":{"div":6,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G8638A","C21548T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188236T","C188339T","-196615A"],"OPG037":["D296N"]},"labels":{"aa":"OPG037: D296N"}},"children":[{"name":"OQ503753","node_attrs":{"div":6,"accession":"OQ503753","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OQ503753/2022-11-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-11-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-110466/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OQ503752","node_attrs":{"div":6,"accession":"OQ503752","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OQ503752/2022-11-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-11-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-118017/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000257","node_attrs":{"div":8,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T607-","C47820T","C68218T","A196615-"],"OPG085":["R105Q"]},"labels":{"aa":"OPG085: R105Q"}},"children":[{"name":"OR427346","node_attrs":{"div":8,"accession":"OR427346","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OR427346/2023-04-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-04-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-048416/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-"]}}},{"name":"OR427341","node_attrs":{"div":10,"accession":"OR427341","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OR427341/2023-03-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-03-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-039072/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G156482A","C175867T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG205":["S71F"]},"labels":{"aa":"OPG205: S71F"}}},{"name":"OR427343","node_attrs":{"div":9,"accession":"OR427343","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OR427343/2023-03-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-03-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-038917/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G100939A"]}}},{"name":"OR427340","node_attrs":{"div":8,"accession":"OR427340","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OR427340/2023-02-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-02-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-028603/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR427339","node_attrs":{"div":8,"accession":"OR427339","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OR427339/2023-01-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-01-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-014981/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","A196614-"]}}},{"name":"OR427336","node_attrs":{"div":9,"accession":"OR427336","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OR427336/2023-01-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-01-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-019613/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C165586T","-196615A"]}}},{"name":"NODE_0000258","node_attrs":{"div":10,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G12239A","G12488A","-196615A"],"OPG023":["S138L","S221F"]},"labels":{"aa":"OPG023: S138L, S221F"}},"children":[{"name":"OQ503756","node_attrs":{"div":10,"accession":"OQ503756","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OQ503756/2022-12-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2022-12-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-126801/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OQ979624","node_attrs":{"div":10,"accession":"OQ979624","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OQ979624/2023-02-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-02-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-028492/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR427347","node_attrs":{"div":10,"accession":"OR427347","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OR427347/2023-02-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-02-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-025109/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR427345","node_attrs":{"div":11,"accession":"OR427345","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OR427345/2023-03-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-03-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-036395/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T607-","G12748A","A196615-"]}}},{"name":"OR427342","node_attrs":{"div":11,"accession":"OR427342","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OR427342/2023-01-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-01-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-014057/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C146485T"]}}}]},{"name":"NODE_0000259","node_attrs":{"div":9,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C102741T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG122":["S105L"]},"labels":{"aa":"OPG122: S105L"}},"children":[{"name":"OQ979623","node_attrs":{"div":10,"accession":"OQ979623","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OQ979623/2023-04-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-04-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-048370/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C70252T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR427335","node_attrs":{"div":9,"accession":"OR427335","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OR427335/2023-04-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-04-XX"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-043227/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR499962","node_attrs":{"div":9,"accession":"OR499962","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499962/2023-04-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-04-12"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00505/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR499963","node_attrs":{"div":10,"accession":"OR499963","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499963/2023-04-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-04-12"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00506/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C1933T","A163211-","A163212-","C163213-","T163214-","G173177A","G195277A"]}}},{"name":"OR499961","node_attrs":{"div":9,"accession":"OR499961","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499961/2023-04-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-04-12"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00504/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR499953","node_attrs":{"div":9,"accession":"OR499953","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499953/2023-04-26"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-04-26"},"lineage":{"value":"B.1.2"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00496/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]}]}]}]}]},{"name":"NODE_0000260","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G53326A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T"]}},"children":[{"name":"OP526857","node_attrs":{"div":4,"accession":"OP526857","author":{"author":"Gigante,C.M.,Plumb,M.,Ruprecht,A.,Zhao,H.,Wicker,V.,Wilkins,K.,Matheny,A.,Khan,T.,Davidson,W.,Sheth,M.,Burgin,A.,Burroughs,M.,Padilla,J.,Lee,J.S.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Garfin,J.,Tate,L.,Hubsmith,S.J.,Mendoza,R.M.,Stanek,D.,Gillani,S.,Lee,M.,Mangla,A.,Blythe,D.,SierraPatev,S.,Carpenter-Azevedo,K.,Huard,R.C.,Gallagher,G.,Hall,J.,Ash,S.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Damon,I.,Satheshkumar,P.S.,McCollum,A.M.,Hutson,C.L.,Wang,X.,Li,Y.","value":"Gigante,C.M.,Plumb,M.,Ruprecht,A.,Zhao,H.,Wicker,V.,Wilkins,K.,Matheny,A.,Khan,T.,Davidson,W.,Sheth,M.,Burgin,A.,Burroughs,M.,Padilla,J.,Lee,J.S.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Garfin,J.,Tate,L.,Hubsmith,S.J.,Mendoza,R.M.,Stanek,D.,Gillani,S.,Lee,M.,Mangla,A.,Blythe,D.,SierraPatev,S.,Carpenter-Azevedo,K.,Huard,R.C.,Gallagher,G.,Hall,J.,Ash,S.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Damon,I.,Satheshkumar,P.S.,McCollum,A.M.,Hutson,C.L.,Wang,X.,Li,Y."},"strain_display":{"value":"USA/OP526857/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_FL0052"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G22643A","G78034A","C138137T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G182049-","A182050-","T182051-","G182052-","C182053-","T182054-","A182055-","G182056-","T182057-","T182058-","T182059-","T182060-","A182061-","G182062-","A182063-","A182064-","T182065-","A182066-","A182067-","C182068-","A182069-","T182070-","T182071-","A182072-","G182073-","T182074-","A182075-","A182076-","A182077-","C182078-","G182079-","A182080-","T182081-","A182082-","C182083-","T182084-","T182085-","C182086-","T182087-","G182088-","A182089-","A182090-","G182091-","A182092-","A182093-","A182094-","T182095-","T182096-","T182097-","T182098-","G182099-","C182100-","T182101-","A182102-","A182103-","T182104-","G182105-","C182106-","T182107-","A182108-","A182109-","C182110-","A182111-","G182112-","G182113-","A182114-","A182115-","C182116-","T182117-","A182118-","G182119-","T182120-","T182121-","C182122-","A182123-","T182124-","C182125-","C182126-","G182127-","A182128-","C182129-","A182130-","C182131-","C182132-","T182133-","T182134-","C182135-","A182136-","T182137-","A182138-","T182139-","C182140-","T182141-","T182142-","C182143-","C182144-","A182145-","C182146-","C182147-","A182148-","A182149-","T182150-","A182151-","T182152-","C182153-","A182154-","C182155-","T182156-","G182157-","A182158-","A182159-","T182160-","G182161-","T182162-","T182163-","T182164-","G182165-","A182166-","A182167-","A182168-","A182169-","C182170-","A182171-","T182172-","T182173-","A182174-","A182175-","T182176-","C182177-","A182178-","A182179-","T182180-","A182181-","A182182-","T182183-","G182184-","T182185-","G182186-","T182187-","C182188-","G182189-","A182190-","T182191-","T182192-","A182193-","A182194-","T182195-","G182196-","A182197-","T182198-","G182199-","T182200-","A182201-","C182202-","T182203-","T182204-","A182205-","T182206-","A182207-","A182208-","C182209-","A182210-","C182211-","A182212-","A182213-","A182214-","A182215-","T182216-","A182217-","T182218-","G182219-","A182220-","A182221-","T182222-","G182223-","T182224-","A182225-","A182226-","C182227-","A182228-","T182229-","C182230-","T182231-","A182232-","A182233-","T182234-","T182235-","G182236-","T182237-","G182238-","A182239-","T182240-","A182241-","A182242-","A182243-","T182244-","G182245-","C182246-","T182247-","C182248-","A182249-","A182250-","T182251-","G182252-","A182253-","A182254-","T182255-","T182256-","T182257-","G182258-","A182259-","T182260-","G182261-","G182262-","C182263-","A182264-","T182265-","C182266-","C182267-","G182268-","T182269-","T182270-","A182271-","T182272-","T182273-","C182274-","C182275-","T182276-","G182277-","C182278-","A182279-","G182280-","T182281-","T182282-","A182283-","A182284-","T182285-","G182286-","A182287-","A182288-","T182289-","T182290-","T182291-","A182292-","A182293-","C182294-","A182295-","A182296-","T182297-","A182298-","C182299-","G182300-","T182301-","T182302-","G182303-","A182304-","T182305-","G182306-","A182307-","A182308-","A182309-","A182310-","T182311-","T182312-","G182313-","G182314-","T182315-","G182316-","T182317-","A182318-","A182319-","A182320-","A182321-","G182322-","A182323-","T182324-","G182325-","A182326-","T182327-","G182328-","A182329-","A182330-","A182331-","A182332-","C182333-","A182334-","A182335-","T182336-","A182337-","C182338-","G182339-","G182340-","T182341-","A182342-","T182343-","A182344-","T182345-","A182346-","A182347-","A182348-","T182349-","A182350-","T182351-","T182352-","A182353-","T182354-","A182355-","A182356-","T182357-","T182358-","G182359-","T182360-","A182361-","A182362-","A182363-","C182364-","T182365-","A182366-","A182367-","C182368-","T182369-","A182370-","C182371-","A182372-","A182373-","A182374-","T182375-","T182376-","C182377-","T182378-","A182379-","C182380-","A182381-","T182382-","G182383-","T182384-","G182385-","A182386-","T182387-","G182388-","A182389-","G182390-","T182391-","T182392-","A182393-","A182394-","T182395-","C182396-","A182397-","A182398-","T182399-","T182400-","T182401-","A182402-","G182403-","A182404-","T182405-","G182406-","A182407-","A182408-","G182409-","T182410-","C182411-","A182412-","T182413-","T182414-","A182415-","A182416-","C182417-","A182418-","A182419-","C182420-","A182421-","T182422-","A182423-","A182424-","C182425-","T182426-","C182427-","T182428-","G182429-","A182430-","C182431-","A182432-","A182433-","A182434-","T182435-","A182436-","T182437-","T182438-","A182439-","T182440-","A182441-","C182442-","A182443-","C182444-","A182445-","A182446-","T182447-","A182448-","G182449-","T182450-","G182451-","T182452-","T182453-","T182454-","C182455-","G182456-","A182457-","C182458-","A182459-","A182460-","C182461-","T182462-","A182463-","A182464-","C182465-","A182466-","G182467-","C182468-","A182469-","G182470-","A182471-","A182472-","A182473-","A182474-","A182475-","G182476-","A182477-","C182478-","G182479-","A182480-","G182481-","A182482-","T182483-","C182484-","T182485-","G182486-","A182487-","A182488-","T182489-","G182490-","A182491-","T182492-","G182493-","A182494-","G182495-","T182496-","T182497-","T182498-","G182499-","A182500-","A182501-","T182502-","T182503-","T182504-","T182505-","C182506-","C182507-","A182508-","C182509-","T182510-","T182511-","C182512-","C182513-","A182514-","A182515-","G182516-","G182517-","A182518-","A182519-","T182520-","T182521-","A182522-","G182523-","A182524-","T182525-","T182526-","G182527-","T182528-","C182529-","T182530-","T182531-","T182532-","A182533-","C182534-","G182535-","A182536-","A182537-","T182538-","C182539-","A182540-","T182541-","A182542-","T182543-","G182544-","G182545-","T182546-","G182547-","T182548-","A182549-","A182550-","A182551-","C182552-","G182553-","A182554-","T182555-","G182556-","A182557-","T182558-","A182559-","T182560-","A182561-","A182562-","G182563-","T182564-","C182565-","A182566-","T182567-","T182568-","G182569-","T182570-","T182571-","T182572-","T182573-","G182574-","C182575-","A182576-","T182577-","C182578-","A182579-","C182580-","C182581-","T182582-","A182583-","G182584-","A182585-","C182586-","G182587-","T182588-","A182589-","G182590-","A182591-","C182592-","G182593-","A182594-","T182595-","C182596-","T182597-","G182598-","A182599-","C182600-","G182601-","A182602-","C182603-","A182604-","A182605-","A182606-","A182607-","A182608-","G182609-","G182610-","A182611-","G182612-","T182613-","A182614-","C182615-","A182616-","T182617-","G182618-","G182619-","A182620-","C182621-","A182622-","T182623-","G182624-","A182625-","A182626-","A182627-","T182628-","T182629-","A182630-","T182631-","T182632-","C182633-","G182634-","A182635-","C182636-","C182637-","A182638-","C182639-","G182640-","C182641-","G182642-","A182643-","A182644-","A182645-","A182646-","A182647-","A182648-","G182649-","A182650-","T182651-","T182652-","T182653-","A182654-","G182655-","G182656-","A182657-","A182658-","T182659-","A182660-","G182661-","A182662-","C182663-","A182664-","G182665-","T182666-","G182667-","T182668-","T182669-","A182670-","T182671-","T182672-","C182673-","C182674-","T182675-","A182676-","G182677-","A182678-","G182679-","G182680-","T182681-","A182682-","C182683-","A182684-","A182685-","C182686-","C182687-","C182688-","A182689-","T182690-","T182691-","T182692-","C182693-","C182694-","A182695-","A182696-","G182697-","T182698-","A182699-","G182700-","G182701-","T182702-","G182703-","C182704-","A182705-","T182706-","C182707-","T182708-","G182709-","G182710-","T182711-","G182712-","C182713-","A182714-","A182715-","G182716-","T182717-","G182718-","G182719-","T182720-","G182721-","G182722-","T182723-","G182724-","T182725-","T182726-","G182727-","T182728-","A182729-","G182730-","G182731-","A182732-","G182733-","A182734-","T182735-","A182736-","G182737-","T182738-","T182739-","T182740-","C182741-","C182742-","C182743-","A182744-","T182745-","T182746-","T182747-","C182748-","A182749-","A182750-","A182751-","A182752-","T182753-","G182754-","T182755-","T182756-","A182757-","A182758-","A182759-","T182760-","C182761-","G182762-","C182763-","G182764-","T182765-","G182766-","C182767-","C182768-","A182769-","G182770-","T182771-","C182772-","T182773-","A182774-","T182775-","T182776-","G182777-","G182778-","C182779-","G182780-","G182781-","A182782-","A182783-","A182784-","A182785-","A182786-","A182787-","T182788-","A182789-","A182790-","T182791-","G182792-","C182793-","C182794-","T182795-","A182796-","G182797-","A182798-","G182799-","T182800-","A182801-","C182802-","C182803-","T182804-","A182805-","T182806-","T182807-","A182808-","C182809-","T182810-","G182811-","C182812-","T182813-","A182814-","C182815-","C182816-","G182817-","A182818-","A182819-","G182820-","C182821-","T182822-","G182823-","A182824-","T182825-","C182826-","T182827-","A182828-","T182829-","A182830-","T182831-","G182832-","C182833-","A182834-","A182835-","C182836-","T182837-","G182838-","T182839-","A182840-","A182841-","A182842-","T182843-","A182844-","G182845-","A182846-","C182847-","A182848-","A182849-","C182850-","C182851-","C182852-","A182853-","A182854-","G182855-","T182856-","T182857-","A182858-","C182859-","C182860-","A182861-","G182862-","C182863-","A182864-","G182865-","G182866-","T182867-","G182868-","T182869-","T182870-","A182871-","A182872-","A182873-","A182874-","G182875-","T182876-","A182877-","C182878-","T182879-","C182880-","C182881-","G182882-","T182883-","T182884-","T182885-","A182886-","C182887-","A182888-","G182889-","A182890-","G182891-","G182892-","C182893-","G182894-","C182895-","T182896-","T182897-","G182898-","T182899-","G182900-","T182901-","C182902-","T182903-","A182904-","C182905-","G182906-","A182907-","T182908-","A182909-","A182910-","A182911-","C182912-","C182913-","A182914-","A182915-","A182916-","A182917-","G182918-","C182919-","T182920-","T182921-","T182922-","C182923-","T182924-","A182925-","A182926-","T182927-","G182928-","T182929-","T182930-","A182931-","G182932-","A182933-","G182934-","A182935-","G182936-","G182937-","T182938-","A182939-","A182940-","C182941-","T182942-","T182943-","A182944-","T182945-","G182946-","C182947-","T182948-","T182949-","C182950-","G182951-","C182952-","T182953-","C182954-","A182955-","A182956-","T182957-","C182958-","T182959-","G182960-","C182961-","C182962-","A182963-","G182964-","G182965-","A182966-","T182967-","C182968-","A182969-","A182970-","G182971-","T182972-","G182973-","G182974-","C182975-","T182976-","A182977-","T182978-","G182979-","T182980-","T182981-","C182982-","A182983-","T182984-","A182985-","G182986-","A182987-","C182988-","C182989-","A182990-","T182991-","C182992-","T182993-","G182994-","A182995-","T182996-","T182997-","C182998-","T182999-","G183000-","T183001-","T183002-","A183003-","T183004-","T183005-","T183006-","A183007-","T183008-","A183009-","G183010-","C183011-","A183012-","G183013-","T183014-","A183015-","T183016-","A183017-","A183018-","G183019-","A183020-","C183021-","G183022-","G183023-","T183024-","C183025-","A183026-","C183027-","G183028-","T183029-","T183030-","T183031-","A183032-","C183033-","C183034-","T183035-","A183036-","G183037-","T183038-","G183039-","A183040-","T183041-","A183042-","G183043-","C183044-","G183045-","A183046-","T183047-","A183048-","G183049-","T183050-","G183051-","A183052-","T183053-","T183054-","A183055-","T183056-","G183057-","A183058-","G183059-","G183060-","A183061-","T183062-","A183063-","T183064-","A183065-","C183066-","A183067-","A183068-","A183069-","C183070-","T183071-","G183072-","T183073-","T183074-","G183075-","T183076-","T183077-","A183078-","A183079-","G183080-","G183081-","A183082-","A183083-","T183084-","A183085-","T183086-","A183087-","A183088-","T183089-","G183090-","A183091-","A183092-","A183093-","G183094-","A183095-","T183096-","A183097-","T183098-","G183099-","G183100-","T183101-","A183102-","G183103-","A183104-","T183105-","C183106-","A183107-","G183108-","T183109-","C183110-","A183111-","G183112-","T183113-","A183114-","G183115-","A183116-","A183117-","C183118-","A183119-","C183120-","A183121-","G183122-","T183123-","C183124-","A183125-","T183126-","C183127-","A183128-","A183129-","G183130-","T183131-","A183132-","G183133-","T183134-","G183135-","A183136-","A183137-","A183138-","G183139-","C183140-","G183141-","A183142-","T183143-","T183144-","T183145-","T183146-","G183147-","A183148-","A183149-","G183150-","A183151-","T183152-","A183153-","T183154-","A183155-","G183156-","A183157-","T183158-","A183159-","C183160-","T183161-","G183162-","T183163-","T183164-","G183165-","T183166-","T183167-","A183168-","G183169-","G183170-","G183171-","A183172-","A183173-","T183174-","A183175-","T183176-","A183177-","G183178-","A183179-","C183180-","A183181-","A183182-","A183183-","A183184-","A183185-","T183186-","A183187-","T183188-","G183189-","G183190-","C183191-","A183192-","A183193-","T183194-","G183195-","C183196-","A183197-","A183198-","T183199-","G183200-","G183201-","C183202-","A183203-","A183204-","A183205-","A183206-","G183207-","G183208-","A183209-","C183210-","G183211-","T183212-","A183213-","G183214-","T183215-","A183216-","G183217-","T183218-","T183219-","C183220-","C183221-","C183222-","C183223-","T183224-","A183225-","A183226-","A183227-","C183228-","C183229-","T183230-","G183231-","A183232-","T183233-","C183234-","C183235-","A183236-","T183237-","T183238-","A183239-","T183240-","A183241-","T183242-","A183243-","G183244-","T183245-","A183246-","C183247-","T183248-","G183249-","T183250-","T183251-","A183252-","A183253-","G183254-","A183255-","A183256-","A183257-","A183258-","C183259-","A183260-","A183261-","C183262-","T183263-","A183264-","A183265-","A183266-","A183267-","G183268-","T183269-","C183270-","T183271-","A183272-","T183273-","C183274-","T183275-","A183276-","C183277-","T183278-","G183279-","G183280-","T183281-","G183282-","T183283-","A183284-","G183285-","A183286-","C183287-","A183288-","T183289-","A183290-","G183291-","T183292-","T183293-","A183294-","C183295-","A183296-","A183297-","A183298-","A183299-","C183300-","A183301-","A183302-","T183303-","C183304-","A183305-","G183306-","A183307-","C183308-","T183309-","A183310-","T183311-","T183312-","C183313-","T183314-","C183315-","T183316-","A183317-","T183318-","T183319-","A183320-","C183321-","C183322-","T183323-","G183324-","A183325-","C183326-","G183327-","T183328-","T183329-","A183330-","A183331-","T183332-","A183333-","C183334-","T183335-","G183336-","G183337-","C183338-","A183339-","G183340-","T183341-","T183342-","C183343-","T183344-","A183345-","T183346-","T183347-","G183348-","T183349-","G183350-","T183351-","C183352-","A183353-","C183354-","C183355-","T183356-","C183357-","T183358-","C183359-","A183360-","C183361-","C183362-","A183363-","G183364-","A183365-","A183366-","A183367-","A183368-","G183369-","G183370-","A183371-","G183372-","C183373-","T183374-","A183375-","C183376-","T183377-","A183378-","G183379-","A183380-","C183381-","G183382-","A183383-","C183384-","G183385-","A183386-","C183387-","C183388-","T183389-","A183390-","G183391-","A183392-","C183393-","G183394-","C183395-","C183396-","C183397-","T183398-","A183399-","C183400-","A183401-","A183402-","A183403-","T183404-","G183405-","A183406-","T183407-","G183408-","G183409-","T183410-","C183411-","T183412-","A183413-","C183414-","A183415-","G183416-","A183417-","G183418-","T183419-","C183420-","C183421-","A183422-","A183423-","A183424-","T183425-","C183426-","C183427-","T183428-","C183429-","C183430-","T183431-","C183432-","T183433-","C183434-","C183435-","G183436-","T183437-","A183438-","A183439-","T183440-","C183441-","C183442-","A183443-","C183444-","T183445-","T183446-","C183447-","C183448-","T183449-","C183450-","A183451-","A183452-","C183453-","A183454-","T183455-","G183456-","A183457-","T183458-","G183459-","A183460-","T183461-","T183462-","A183463-","T183464-","T183465-","C183466-","T183467-","C183468-","C183469-","T183470-","C183471-","C183472-","A183473-","C183474-","A183475-","A183476-","G183477-","T183478-","A183479-","C183480-","A183481-","C183482-","A183483-","G183484-","A183485-","C183486-","C183487-","T183488-","C183489-","C183490-","A183491-","C183492-","C183493-","A183494-","C183495-","T183496-","T183497-","C183498-","C183499-","T183500-","C183501-","C183502-","T183503-","A183504-","A183505-","A183506-","C183507-","C183508-","A183509-","G183510-","T183511-","C183512-","C183513-","A183514-","A183515-","A183516-","A183517-","T183518-","T183519-","C183520-","G183521-","C183522-","C183523-","A183524-","C183525-","A183526-","A183527-","C183528-","T183529-","T183530-","C183531-","C183532-","C183533-","C183534-","C183535-","T183536-","A183537-","G183538-","A183539-","C183540-","C183541-","A183542-","G183543-","T183544-","A183545-","G183546-","G183547-","T183548-","C183549-","A183550-","A183551-","T183552-","T183553-","A183554-","C183555-","T183556-","A183557-","C183558-","C183559-","T183560-","C183561-","C183562-","T183563-","C183564-","C183565-","T183566-","A183567-","T183568-","A183569-","G183570-","A183571-","T183572-","C183573-","A183574-","A183575-","C183576-","C183577-","A183578-","G183579-","A183580-","T183581-","A183582-","A183583-","A183584-","G183585-","G183586-","A183587-","T183588-","T183589-","T183590-","A183591-","G183592-","T183593-","A183594-","A183595-","G183596-","T183597-","T183598-","T183599-","G183600-","T183601-","A183602-","T183603-","C183604-","A183605-","C183606-","C183607-","T183608-","A183609-","G183610-","A183611-","C183612-","G183613-","G183614-","T183615-","G183616-","T183617-","A183618-","G183619-","A183620-","A183621-","G183622-","A183623-","G183624-","C183625-","A183626-","A183627-","G183628-","C183629-","T183630-","C183631-","T183632-","G183633-","G183634-","A183635-","G183636-","T183637-","C183638-","A183639-","T183640-","A183641-","T183642-","G183643-","T183644-","G183645-","G183646-","T183647-","A183648-","T183649-","G183650-","A183651-","T183652-","A183653-","C183654-","A183655-","A183656-","T183657-","C183658-","A183659-","A183660-","A183661-","A183662-","C183663-","C183664-","A183665-","A183666-","A183667-","C183668-","G183669-","A183670-","T183671-","G183672-","A183673-","T183674-","A183675-","C183676-","C183677-","T183678-","A183679-","T183680-","T183681-","C183682-","A183683-","C183684-","T183685-","T183686-","C183687-","T183688-","T183689-","C183690-","A183691-","A183692-","C183693-","G183694-","A183695-","T183696-","C183697-","A183698-","A183699-","A183700-","A183701-","A183702-","T183703-","T183704-","G183705-","A183706-","A183707-","C183708-","C183709-","A183710-","G183711-","A183712-","A183713-","T183714-","A183715-","T183716-","G183717-","T183718-","G183719-","G183720-","A183721-","G183722-","G183723-","T183724-","T183725-","G183726-","G183727-","T183728-","A183729-","A183730-","T183731-","G183732-","G183733-","T183734-","A183735-","T183736-","A183737-","C183738-","C183739-","C183740-","A183741-","A183742-","G183743-","A183744-","A183745-","C183746-","A183747-","A183748-","T183749-","G183750-","T183751-","T183752-","C183753-","C183754-","T183755-","G183756-","T183757-","A183758-","A183759-","T183760-","A183761-","G183762-","G183763-","T183764-","A183765-","A183766-","T183767-","A183768-","A183769-","A183770-","C183771-","A183772-","T183773-","A183774-","G183775-","T183776-","A183777-","A183778-","A183779-","A183780-","A183781-","A183782-","T183783-","A183784-","T183785-","A183786-","C183787-","A183788-","T183789-","C183790-","G183791-","A183792-","C183793-","G183794-","A183795-","T183796-","G183797-","T183798-","C183799-","A183800-","A183801-","A183802-","A183803-","A183804-","T183805-","A183806-","T183807-","C183808-","A183809-","A183810-","C183811-","A183812-","A183813-","A183814-","A183815-","T183816-","T183817-","T183818-","G183819-","A183820-","T183821-","A183822-","A183823-","A183824-","T183825-","C183826-","T183827-","A183828-","C183829-","G183830-","G183831-","C183832-","A183833-","T183834-","T183835-","T183836-","G183837-","G183838-","A183839-","G183840-","C183841-","A183842-","G183843-","C183844-","A183845-","A183846-","T183847-","G183848-","T183849-","T183850-","A183851-","C183852-","T183853-","A183854-","A183855-","C183856-","T183857-","G183858-","G183859-","T183860-","C183861-","A183862-","G183863-","C183864-","A183865-","G183866-","G183867-","C183868-","C183869-","A183870-","T183871-","T183872-","A183873-","G183874-","C183875-","C183876-","A183877-","A183878-","C183879-","A183880-","G183881-","A183882-","C183883-","T183884-","A183885-","G183886-","A183887-","T183888-","C183889-","A183890-","A183891-","C183892-","T183893-","A183894-","C183895-","G183896-","T183897-","T183898-","G183899-","A183900-","G183901-","T183902-","A183903-","G183904-","A183905-","A183906-","A183907-","A183908-","G183909-","A183910-","T183911-","C183912-","A183913-","G183914-","A183915-","T183916-","G183917-","A183918-","G183919-","T183920-","A183921-","A183922-","G183923-","G183924-","A183925-","A183926-","G183927-","A183928-","A183929-","A183930-","A183931-","G183932-","A183933-","T183934-","A183935-","T183936-","T183937-","C183938-","G183939-","A183940-","A183941-","G183942-","C183943-","A183944-","G183945-","T183946-","T183947-","A183948-","C183949-","A183950-","A183951-","T183952-","G183953-","A183954-","G183955-","T183956-","C183957-","T183958-","A183959-","T183960-","C183961-","A183962-","A183963-","C183964-","T183965-","A183966-","T183967-","A183968-","G183969-","G183970-","T183971-","T183972-","C183973-","A183974-","A183975-","C183976-","G183977-","T183978-","T183979-","G183980-","A183981-","C183982-","G183983-","T183984-","C183985-","T183986-","G183987-","C183988-","A183989-","G183990-","G183991-","T183992-","A183993-","T183994-","G183995-","A183996-","C183997-","G183998-","G183999-","G184000-","T184001-","G184002-","G184003-","T184004-","C184005-","C184006-","A184007-","A184008-","A184009-","A184010-","C184011-","T184012-","A184013-","A184014-","T184015-","G184016-","A184017-","T184018-","T184019-","G184020-","C184021-","A184022-","G184023-","G184024-","A184025-","A184026-","T184027-","G184028-","G184029-","C184030-","T184031-","A184032-","T184033-","A184034-","A184035-","C184036-","G184037-","G184038-","C184039-","T184040-","A184041-","T184042-","A184043-","A184044-","C184045-","T184046-","G184047-","G184048-","T184049-","A184050-","T184051-","A184052-","A184053-","T184054-","A184055-","G184056-","A184057-","T184058-","A184059-","C184060-","G184061-","A184062-","T184063-","A184064-","A184065-","A184066-","A184067-","G184068-","A184069-","T184070-","A184071-","T184072-","A184073-","T184074-","A184075-","T184076-","T184077-","A184078-","C184079-","A184080-","T184081-","G184082-","T184083-","T184084-","T184085-","T184086-","C184087-","A184088-","G184089-","G184090-","A184091-","C184092-","A184093-","G184094-","G184095-","A184096-","G184097-","A184098-","G184099-","G184100-","C184101-","C184102-","A184103-","G184104-","T184105-","A184106-","G184107-","A184108-","T184109-","C184110-","C184111-","T184112-","G184113-","T184114-","T184115-","A184116-","T184117-","T184118-","A184119-","A184120-","A184121-","T184122-","T184123-","A184124-","T184125-","T184126-","T184127-","A184128-","A184129-","T184130-","A184131-","A184132-","G184133-","T184134-","A184135-","C184136-","A184137-","C184138-","T184139-","G184140-","G184141-","C184142-","T184143-","T184144-","A184145-","A184146-","T184147-","G184148-","T184149-","C184150-","C184151-","G184152-","A184153-","T184154-","A184155-","A184156-","T184157-","A184158-","A184159-","T184160-","A184161-","A184162-","A184163-","A184164-","T184165-","G184166-","G184167-","G184168-","T184169-","G184170-","T184171-","A184172-","A184173-","G184174-","A184175-","A184176-","A184177-","A184178-","T184179-","G184180-","T184181-","T184182-","T184183-","G184184-","A184185-","C184186-","A184187-","C184188-","C184189-","C184190-","G184191-","G184192-","T184193-","G184194-","A184195-","C184196-","G184197-","A184198-","C184199-","A184200-","C184201-","A184202-","C184203-","T184204-","T184205-","A184206-","T184207-","T184208-","T184209-","A184210-","T184211-","A184212-","T184213-","C184214-","G184215-","C184216-","A184217-","T184218-","A184219-","C184220-","A184221-","G184222-","A184223-","A184224-","A184225-","C184226-","G184227-","A184228-","T184229-","A184230-","C184231-","C184232-","A184233-","G184234-","T184235-","T184236-","T184237-","T184238-","A184239-","A184240-","A184241-","C184242-","A184243-","G184244-","A184245-","A184246-","T184247-","A184248-","C184249-","G184250-","G184251-","A184252-","T184253-","G184254-","C184255-","G184256-","A184257-","T184258-","G184259-","G184260-","C184261-","T184262-","T184263-","T184264-","G184265-","T184266-","A184267-","T184268-","T184269-","T184270-","C184271-","T184272-","T184273-","A184274-","G184275-","A184276-","T184277-","G184278-","T184279-","T184280-","A184281-","T184282-","C184283-","G184284-","A184285-","T184286-","T184287-","C184288-","A184289-","G184290-","A184291-","G184292-","A184293-","T184294-","C184295-","C184296-","T184297-","A184298-","T184299-","A184300-","T184301-","C184302-","T184303-","A184304-","A184305-","A184306-","C184307-","A184308-","C184309-","A184310-","T184311-","C184312-","A184313-","A184314-","A184315-","T184316-","T184317-","T184318-","A184319-","G184320-","T184321-","T184322-","C184323-","T184324-","A184325-","G184326-","A184327-","G184328-","T184329-","A184330-","T184331-","C184332-","A184333-","A184334-","C184335-","T184336-","A184337-","A184338-","A184339-","G184340-","G184341-","T184342-","G184343-","G184344-","C184345-","T184346-","T184347-","G184348-","C184349-","C184350-","C184351-","C184352-","A184353-","T184354-","A184355-","G184356-","G184357-","A184358-","A184359-","C184360-","A184361-","T184362-","T184363-","A184364-","A184365-","G184366-","A184367-","T184368-","C184369-","T184370-","G184371-","T184372-","A184373-","G184374-","A184375-","T184376-","G184377-","T184378-","G184379-","G184380-","A184381-","C184382-","A184383-","T184384-","A184385-","A184386-","C184387-","T184388-","G184389-","C184390-","G184391-","T184392-","A184393-","T184394-","A184395-","C184396-","A184397-","A184398-","T184399-","A184400-","T184401-","T184402-","A184403-","T184404-","A184405-","T184406-","G184407-","A184408-","T184409-","A184410-","C184411-","A184412-","G184413-","C184414-","G184415-","G184416-","A184417-","T184418-","A184419-","A184420-","T184421-","A184422-","T184423-","T184424-","A184425-","A184426-","G184427-","A184428-","A184429-","A184430-","T184431-","A184432-","C184433-","A184434-","A184435-","G184436-","T184437-","T184438-","T184439-","A184440-","T184441-","C184442-","A184443-","G184444-","A184445-","A184446-","T184447-","G184448-","G184449-","C184450-","A184451-","A184452-","C184453-","G184454-","C184455-","T184456-","A184457-","C184458-","T184459-","A184460-","T184461-","C184462-","C184463-","A184464-","A184465-","A184466-","C184467-","A184468-","T184469-","C184470-","C184471-","A184472-","G184473-","T184474-","T184475-","A184476-","T184477-","T184478-","A184479-","G184480-","A184481-","T184482-","T184483-","G184484-","A184485-","C184486-","A184487-","T184488-","G184489-","T184490-","G184491-","G184492-","T184493-","T184494-","T184495-","A184496-","G184497-","C184498-","A184499-","G184500-","C184501-","A184502-","A184503-","C184504-","A184505-","T184506-","T184507-","G184508-","G184509-","T184510-","G184511-","A184512-","T184513-","T184514-","A184515-","A184516-","A184517-","C184518-","C184519-","G184520-","T184521-","A184522-","C184523-","G184524-","A184525-","G184526-","G184527-","T184528-","A184529-","C184530-","C184531-","C184532-","A184533-","T184534-","C184535-","A184536-","G184537-","T184538-","G184539-","A184540-","T184541-","A184542-","T184543-","G184544-","C184545-","A184546-","A184547-","C184548-","T184549-","A184550-","C184551-","T184552-","A184553-","A184554-","A184555-","A184556-","A184557-","T184558-","G184559-","G184560-","C184561-","G184562-","A184563-","C184564-","G184565-","C184566-","C184567-","T184568-","G184569-","G184570-","T184571-","G184572-","A184573-","A184574-","C184575-","C184576-","A184577-","G184578-","A184579-","A184580-","T184581-","C184582-","C184583-","A184584-","C184585-","T184586-","A184587-","A184588-","A184589-","T184590-","C184591-","T184592-","A184593-","T184594-","A184595-","C184596-","C184597-","A184598-","T184599-","C184600-","C184601-","G184602-","A184603-","T184604-","G184605-","T184606-","C184607-","T184608-","G184609-","T184610-","G184611-","A184612-","T184613-","A184614-","G184615-","G184616-","T184617-","A184618-","T184619-","C184620-","C184621-","T184622-","C184623-","T184624-","A184625-","A184626-","A184627-","G184628-","A184629-","A184630-","A184631-","T184632-","T184633-","C184634-","T184635-","A184636-","T184637-","C184638-","T184639-","T184640-","T184641-","T184642-","A184643-","G184644-","C184645-","T184646-","G184647-","G184648-","T184649-","G184650-","G184651-","T184652-","T184653-","G184654-","T184655-","C184656-","C184657-","C184658-","T184659-","A184660-","T184661-","G184662-","A184663-","T184664-","A184665-","C184666-","A184667-","T184668-","C184669-","T184670-","C184671-","A184672-","A184673-","A184674-","C184675-","T184676-","T184677-","T184678-","T184679-","A184680-","T184681-","T184682-","G184683-","T184684-","A184685-","C184686-","A184687-","T184688-","A184689-","C184690-","T184691-","A184692-","C184693-","T184694-","T184695-","G184696-","C184697-","A184698-","G184699-","T184700-","A184701-","T184702-","T184703-","C184704-","T184705-","A184706-","C184707-","T184708-","A184709-","A184710-","G184711-","A184712-","A184713-","C184714-","A184715-","G184716-","C184717-","T184718-","A184719-","C184720-","A184721-","C184722-","G184723-","G184724-","G184725-","A184726-","T184727-","C184728-","A184729-","G184730-","T184731-","T184732-","T184733-","A184734-","G184735-","A184736-","A184737-","A184738-","C184739-","A184740-","G184741-","A184742-","T184743-","G184744-","G184745-","G184746-","T184747-","G184748-","T184749-","T184750-","A184751-","C184752-","A184753-","A184754-","A184755-","A184756-","T184757-","C184758-","C184759-","A184760-","T184761-","T184762-","T184763-","A184764-","G184765-","A184766-","C184767-","A184768-","A184769-","G184770-","A184771-","A184772-","G184773-","G184774-","G184775-","A184776-","C184777-","A184778-","T184779-","A184780-","T184781-","A184782-","A184783-","G184784-","C184785-","A184786-","A184787-","C184788-","T184789-","G184790-","T184791-","T184792-","T184793-","A184794-","C184795-","C184796-","T184797-","T184798-","T184799-","A184800-","G184801-","C184802-","A184803-","A184804-","A184805-","T184806-","A184807-","C184808-","G184809-","A184810-","T184811-","T184812-","T184813-","T184814-","A184815-","A184816-","C184817-","G184818-","A184819-","C184820-","A184821-","C184822-","C184823-","A184824-","T184825-","A184826-","A184827-","T184828-","C184829-","G184830-","A184831-","T184832-","C184833-","C184834-","T184835-","A184836-","A184837-","T184838-","G184839-","G184840-","T184841-","G184842-","T184843-","G184844-","G184845-","T184846-","G184847-","G184848-","G184849-","T184850-","C184851-","A184852-","T184853-","G184854-","C184855-","T184856-","A184857-","G184858-","C184859-","T184860-","T184861-","T184862-","T184863-","G184864-","T184865-","A184866-","C184867-","C184868-","A184869-","A184870-","T184871-","A184872-","G184873-","A184874-","A184875-","G184876-","C184877-","A184878-","G184879-","C184880-","A184881-","A184882-","C184883-","C184884-","A184885-","A184886-","T184887-","G184888-","T184889-","T184890-","T184891-","C184892-","T184893-","G184894-","G184895-","T184896-","C184897-","C184898-","G184899-","A184900-","A184901-","C184902-","C184903-","T184904-","A184905-","T184906-","G184907-","A184908-","T184909-","A184910-","T184911-","T184912-","G184913-","G184914-","A184915-","A184916-","G184917-","A184918-","T184919-","G184920-","T184921-","A184922-","T184923-","C184924-","A184925-","T184926-","C184927-","G184928-","T184929-","G184930-","T184931-","A184932-","G184933-","T184934-","T184935-","C184936-","T184937-","A184938-","G184939-","A184940-","A184941-","C184942-","T184943-","A184944-","G184945-","A184946-","A184947-","A184948-","A184949-","A184950-","T184951-","A184952-","T184953-","A184954-","C184955-","G184956-","T184957-","A184958-","A184959-","A184960-","A184961-","C184962-","T184963-","G184964-","G184965-","G184966-","A184967-","A184968-","T184969-","A184970-","T184971-","T184972-","T184973-","A184974-","A184975-","T184976-","G184977-","C184978-","T184979-","G184980-","A184981-","A184982-","G184983-","G184984-","T184985-","T184986-","T184987-","T184988-","A184989-","A184990-","T184991-","A184992-","G184993-","T184994-","T184995-","T184996-","T184997-","G184998-","T184999-","A185000-","C185001-","T185002-","A185003-","A185004-","A185005-","T185006-","T185007-","G185008-","T185009-","C185010-","C185011-","A185012-","A185013-","C185014-","T185015-","G185016-","G185017-","G185018-","T185019-","C185020-","T185021-","A185022-","C185023-","A185024-","C185025-","C185026-","T185027-","A185028-","C185029-","A185030-","T185031-","A185032-","C185033-","A185034-","T185035-","C185036-","A185037-","A185038-","A185039-","C185040-","A185041-","T185042-","A185043-","A185044-","A185045-","A185046-","A185047-","T185048-","G185049-","C185050-","G185051-","G185052-","A185053-","C185054-","A185055-","G185056-","T185057-","A185058-","A185059-","C185060-","A185061-","A185062-","T185063-","G185064-","T185065-","T185066-","A185067-","T185068-","C185069-","A185070-","T185071-","A185072-","G185073-","A185074-","G185075-","C185076-","T185077-","A185078-","C185079-","C185080-","T185081-","G185082-","T185083-","A185084-","G185085-","G185086-","T185087-","G185088-","A185089-","T185090-","T185091-","A185092-","C185093-","G185094-","G185095-","C185096-","A185097-","C185098-","A185099-","G185100-","C185101-","C185102-","A185103-","A185104-","A185105-","T185106-","T185107-","G185108-","T185109-","A185110-","T185111-","T185112-","C185113-","A185114-","G185115-","C185116-","A185117-","A185118-","C185119-","A185120-","A185121-","A185122-","A185123-","C185124-","C185125-","A185126-","T185127-","C185128-","G185129-","A185130-","G185131-","G185132-","A185133-","T185134-","A185135-","G185136-","C185137-","T185138-","G185139-","T185140-","G185141-","T185142-","T185143-","C185144-","T185145-","G185146-","C185147-","A185148-","C185149-","A185150-","C185151-","A185152-","T185153-","A185154-","A185155-","C185156-","T185157-","A185158-","T185159-","G185160-","A185161-","T185162-","A185163-","A185164-","A185165-","C185166-","G185167-","A185168-","T185169-","T185170-","C185171-","A185172-","A185173-","A185174-","T185175-","C185176-","A185177-","G185178-","A185179-","T185180-","A185181-","T185182-","T185183-","A185184-","T185185-","A185186-","G185187-","T185188-","T185189-","C185190-","T185191-","A185192-","A185193-","T185194-","G185195-","T185196-","T185197-","T185198-","A185199-","A185200-","T185201-","A185202-","A185203-","A185204-","A185205-","A185206-","C185207-","A185208-","G185209-","C185210-","G185211-","G185212-","T185213-","A185214-","T185215-","T185216-","C185217-","C185218-","A185219-","T185220-","T185221-","T185222-","T185223-","G185224-","G185225-","A185226-","G185227-","C185228-","A185229-","T185230-","G185231-","T185232-","A185233-","C185234-","A185235-","C185236-","A185237-","G185238-","G185239-","A185240-","A185241-","G185242-","T185243-","G185244-","T185245-","A185246-","A185247-","C185248-","T185249-","A185250-","G185251-","T185252-","A185253-","A185254-","A185255-","A185256-","A185257-","T185258-","A185259-","G185260-","A185261-","A185262-","T185263-","G185264-","T185265-","T185266-","T185267-","G185268-","C185269-","C185270-","A185271-","C185272-","A185273-","T185274-","T185275-","G185276-","G185277-","C185278-","T185279-","A185280-","G185281-","A185282-","G185283-","G185284-","A185285-","A185286-","T185287-","G185288-","C185289-","C185290-","G185291-","T185292-","T185293-","T185294-","A185295-","G185296-","A185297-","T185298-","C185299-","A185300-","A185301-","C185302-","G185303-","T185304-","A185305-","T185306-","T185307-","G185308-","C185309-","G185310-","A185311-","T185312-","A185313-","A185314-","C185315-","A185316-","G185317-","A185318-","C185319-","G185320-","A185321-","C185322-","G185323-","A185324-","T185325-","C185326-","A185327-","G185328-","G185329-","T185330-","T185331-","G185332-","T185333-","T185334-","A185335-","T185336-","T185337-","A185338-","T185339-","G185340-","C185341-","A185342-","G185343-","G185344-","A185345-","A185346-","T185347-","A185348-","C185349-","C185350-","A185351-","T185352-","T185353-","T185354-","C185355-","A185356-","T185357-","G185358-","A185359-","A185360-","G185361-","A185362-","T185363-","A185364-","G185365-","T185366-","G185367-","T185368-","A185369-","G185370-","A185371-","A185372-","A185373-","C185374-","A185375-","G185376-","A185377-","T185378-","A185379-","T185380-","A185381-","C185382-","A185383-","T185384-","T185385-","A185386-","T185387-","G185388-","G185389-","A185390-","C185391-","C185392-","A185393-","G185394-","A185395-","A185396-","A185397-","T185398-","A185399-","A185400-","T185401-","G185402-","T185403-","T185404-","A185405-","A185406-","A185407-","G185408-","G185409-","A185410-","A185411-","A185412-","C185413-","A185414-","T185415-","A185416-","T185417-","G185418-","A185419-","C185420-","A185421-","T185422-","A185423-","A185424-","A185425-","C185426-","A185427-","G185428-","T185429-","A185430-","T185431-","T185432-","G185433-","A185434-","C185435-","C185436-","C185437-","A185438-","C185439-","G185440-","A185441-","G185442-","T185443-","T185444-","A185445-","T185446-","A185447-","A185448-","C185449-","A185450-","A185451-","A185452-","G185453-","T185454-","C185455-","A185456-","A185457-","A185458-","G185459-","A185460-","C185461-","C185462-","C185463-","A185464-","T185465-","T185466-","T185467-","T185468-","C185469-","C185470-","T185471-","G185472-","C185473-","T185474-","C185475-","C185476-","A185477-","T185478-","T185479-","G185480-","A185481-","G185482-","T185483-","G185484-","T185485-","A185486-","A185487-","A185488-","A185489-","T185490-","T185491-","C185492-","A185493-","T185494-","G185495-","G185496-","T185497-","T185498-","G185499-","A185500-","C185501-","A185502-","A185503-","T185504-","T185505-","T185506-","A185507-","G185508-","G185509-","A185510-","A185511-","A185512-","T185513-","G185514-","G185515-","A185516-","T185517-","A185518-","T185519-","G185520-","A185521-","C185522-","A185523-","A185524-","C185525-","C185526-","C185527-","T185528-","A185529-","A185530-","T185531-","T185532-","C185533-","A185534-","T185535-","T185536-","T185537-","T185538-","G185539-","G185540-","G185541-","A185542-","A185543-","G185544-","A185545-","T185546-","G185547-","C185548-","T185549-","A185550-","A185551-","A185552-","A185553-","C185554-","T185555-","A185556-","A185557-","G185558-","A185559-","A185560-","A185561-","C185562-","G185563-","G185564-","A185565-","C185566-","A185567-","T185568-","A185569-","T185570-","A185571-","G185572-","T185573-","G185574-","C185575-","A185576-","A185577-","T185578-","G185579-","A185580-","C185581-","G185582-","A185583-","T185584-","A185585-","A185586-","A185587-","A185588-","G185589-","T185590-","C185591-","C185592-","T185593-","A185594-","C185595-","C185596-","A185597-","T185598-","G185599-","T185600-","A185601-","C185602-","A185603-","G185604-","T185605-","G185606-","A185607-","G185608-","A185609-","A185610-","A185611-","T185612-","A185613-","A185614-","A185615-","A185616-","A185617-","T185618-","A185619-","T185620-","A185621-","G185622-","A185623-","C185624-","T185625-","T185626-","T185627-","G185628-","G185629-","A185630-","T185631-","A185632-","T185633-","A185634-","A185635-","C185636-","T185637-","A185638-","T185639-","G185640-","G185641-","A185642-","G185643-","A185644-","T185645-","A185646-","T185647-","T185648-","A185649-","T185650-","T185651-","T185652-","C185653-","T185654-","A185655-","A185656-","T185657-","A185658-","T185659-","G185660-","G185661-","T185662-","T185663-","T185664-","A185665-","T185666-","C185667-","T185668-","A185669-","C185670-","A185671-","A185672-","T185673-","C185674-","T185675-","A185676-","C185677-","T185678-","A185679-","G185680-","T185681-","C185682-","A185683-","G185684-","G185685-","A185686-","T185687-","T185688-","A185689-","T185690-","G185691-","G185692-","A185693-","G185694-","A185695-","T185696-","G185697-","G185698-","T185699-","A185700-","C185701-","C185702-","A185703-","A185704-","A185705-","T185706-","A185707-","T185708-","A185709-","C185710-","A185711-","T185712-","T185713-","T185714-","A185715-","A185716-","A185717-","T185718-","C185719-","C185720-","G185721-","T185722-","A185723-","A185724-","C185725-","T185726-","A185727-","G185728-","A185729-","T185730-","C185731-","A185732-","G185733-","A185734-","T185735-","C185736-","A185737-","T185738-","G185739-","A185740-","G185741-","T185742-","G185743-","T185744-","G185745-","A185746-","A185747-","T185748-","C185749-","T185750-","A185751-","G185752-","C185753-","T185754-","T185755-","A185756-","G185757-","A185758-","T185759-","C185760-","T185761-","A185762-","A185763-","C185764-","G185765-","T185766-","C185767-","T185768-","A185769-","A185770-","G185771-","G185772-","A185773-","A185774-","G185775-","T185776-","A185777-","A185778-","C185779-","T185780-","G185781-","T185782-","G185783-","A185784-","C185785-","A185786-","T185787-","G185788-","T185789-","C185790-","C185791-","T185792-","G185793-","C185794-","G185795-","T185796-","T185797-","T185798-","A185799-","G185800-","T185801-","A185802-","T185803-","A185804-","C185805-","C185806-","A185807-","A185808-","G185809-","A185810-","A185811-","A185812-","T185813-","A185814-","T185815-","A185816-","T185817-","C185818-","A185819-","A185820-","C185821-","A185822-","T185823-","A185824-","T185825-","G185826-","A185827-","A185828-","G185829-","G185830-","T185831-","C185832-","T185833-","A185834-","T185835-","G185836-","C185837-","T185838-","T185839-","T185840-","A185841-","G185842-","T185843-","G185844-","T185845-","T185846-","A185847-","C185848-","T185849-","A185850-","C185851-","A185852-","T185853-","C185854-","T185855-","A185856-","A185857-","A185858-","G185859-","A185860-","T185861-","C185862-","A185863-","T185864-","T185865-","G185866-","T185867-","G185868-","C185869-","T185870-","A185871-","C185872-","A185873-","G185874-","G185875-","T185876-","A185877-","T185878-","T185879-","G185880-","G185881-","T185882-","T185883-","G185884-","G185885-","T185886-","T185887-","A185888-","A185889-","A185890-","A185891-","T185892-","C185893-","T185894-","A185895-","G185896-","T185897-","G185898-","G185899-","T185900-","T185901-","A185902-","T185903-","G185904-","G185905-","G185906-","A185907-","A185908-","G185909-","G185910-","A185911-","A185912-","G185913-","A185914-","T185915-","G185916-","C185917-","T185918-","G185919-","A185920-","T185921-","A185922-","A185923-","A185924-","C185925-","C185926-","A185927-","C185928-","G185929-","T185930-","G185931-","C185932-","T185933-","T185934-","G185935-","T185936-","T185937-","T185938-","T185939-","C185940-","A185941-","T185942-","C185943-","A185944-","T185945-","T185946-","G185947-","G185948-","A185949-","A185950-","T185951-","T185952-","A185953-","T185954-","T185955-","A185956-","C185957-","A185958-","C185959-","A185960-","C185961-","T185962-","G185963-","T185964-","C185965-","G185966-","T185967-","T185968-","G185969-","G185970-","A185971-","T185972-","T185973-","A185974-","T185975-","T185976-","A185977-","C185978-","T185979-","G185980-","T185981-","T185982-","C185983-","A185984-","T185985-","A185986-","C185987-","G185988-","A185989-","A185990-","G185991-","A185992-","T185993-","A185994-","T185995-","T185996-","T185997-","G185998-","G185999-","A186000-","G186001-","A186002-","A186003-","G186004-","C186005-","A186006-","C186007-","C186008-","T186009-","G186010-","G186011-","C186012-","C186013-","T186014-","G186015-","A186016-","C186017-","T186018-","A186019-","T186020-","G186021-","A186022-","T186023-","C186024-","C186025-","A186026-","T186027-","G186028-","T186029-","A186030-","A186031-","G186032-","T186033-","C186034-","A186035-","T186036-","A186037-","T186038-","A186039-","T186040-","C186041-","C186042-","A186043-","T186044-","A186045-","T186046-","A186047-","G186048-","A186049-","G186050-","T186051-","A186052-","T186053-","A186054-","G186055-","A186056-","G186057-","A186058-","T186059-","A186060-","C186061-","A186062-","T186063-","G186064-","G186065-","A186066-","T186067-","A186068-","G186069-","A186070-","A186071-","T186072-","C186073-","T186074-","A186075-","A186076-","T186077-","G186078-","T186079-","G186080-","T186081-","T186082-","A186083-","C186084-","A186085-","G186086-","C186087-","A186088-","A186089-","C186090-","C186091-","T186092-","C186093-","C186094-","T186095-","T186096-","A186097-","C186098-","A186099-","C186100-","A186101-","T186102-","T186103-","C186104-","G186105-","A186106-","A186107-","T186108-","T186109-","C186110-","A186111-","T186112-","T186113-","C186114-","A186115-","T186116-","G186117-","A186118-","C186119-","A186120-","A186121-","T186122-","T186123-","C186124-","T186125-","A186126-","A186127-","C186128-","G186129-","A186130-","A186131-","T186132-","A186133-","T186134-","G186135-","T186136-","G186137-","G186138-","A186139-","T186140-","A186141-","A186142-","A186143-","G186144-","A186145-","A186146-","A186147-","T186148-","T186149-","A186150-","G186151-","T186152-","A186153-","A186154-","C186155-","A186156-","A186157-","A186158-","T186159-","T186160-","A186161-","A186162-","A186163-","T186164-","G186165-","A186166-","T186167-","C186168-","T186169-","G186170-","T186171-","A186172-","C186173-","A186174-","A186175-","T186176-","G186177-","A186178-","A186179-","T186180-","A186181-","C186182-","A186183-","A186184-","G186185-","A186186-","A186187-","G186188-","A186189-","T186190-","T186191-","A186192-","T186193-","G186194-","G186195-","A186196-","A186197-","T186198-","A186199-","T186200-","A186201-","G186202-","C186203-","G186204-","A186205-","C186206-","G186207-","G186208-","A186209-","T186210-","C186211-","A186212-","T186213-","T186214-","G186215-","C186216-","C186217-","G186218-","G186219-","C186220-","G186221-","T186222-","C186223-","T186224-","A186225-","T186226-","A186227-","A186228-","A186229-","C186230-","A186231-","G186232-","A186233-","T186234-","T186235-","A186236-","G186237-","C186238-","A186239-","A186240-","A186241-","G186242-","G186243-","C186244-","A186245-","T186246-","T186247-","G186248-","A186249-","C186250-","T186251-","T186252-","C186253-","A186254-","G186255-","A186256-","G186257-","G186258-","G186259-","T186260-","A186261-","G186262-","A186263-","G186264-","A186265-","A186266-","A186267-","T186268-","A186269-","G186270-","C186271-","A186272-","A186273-","G186274-","T186275-","G186276-","T186277-","T186278-","A186279-","A186280-","T186281-","A186282-","T186283-","A186284-","G186285-","A186286-","T186287-","G186288-","G186289-","T186290-","A186291-","A186292-","T186293-","C186294-","T186295-","G186296-","T186297-","T186298-","A186299-","G186300-","A186301-","T186302-","A186303-","T186304-","C186305-","G186306-","C186307-","A186308-","T186309-","A186310-","T186311-","C186312-","A186313-","A186314-","G186315-","C186316-","A186317-","G186318-","A186319-","T186320-","A186321-","A186322-","G186323-","G186324-","A186325-","A186326-","A186327-","A186328-","G186329-","A186330-","T186331-","G186332-","G186333-","C186334-","C186335-","G186336-","A186337-","C186338-","A186339-","T186340-","A186341-","C186342-","A186343-","G186344-","A186345-","C186346-","A186347-","A186348-","G186349-","A186350-","A186351-","T186352-","A186353-","A186354-","A186355-","T186356-","G186357-","A186358-","T186359-","A186360-","T186361-","T186362-","A186363-","T186364-","T186365-","A186366-","G186367-","A186368-","G186369-","A186370-","T186371-","T186372-","T186373-","G186374-","T186375-","T186376-","T186377-","A186378-","T186379-","A186380-","C186381-","A186382-","C186383-","A186384-","C186385-","T186386-","C186387-","T186388-","A186389-","T186390-","C186391-","A186392-","G186393-","A186394-","C186395-","A186396-","A186397-","A186398-","G186399-","A186400-","T186401-","A186402-","T186403-","A186404-","A186405-","A186406-","A186407-","G186408-","A186409-","C186410-","A186411-","T186412-","T186413-","A186414-","T186415-","A186416-","G186417-","A186418-","A186419-","T186420-","C186421-","C186422-","G186423-","A186424-","A186425-","G186426-","A186427-","A186428-","G186429-","G186430-","T186431-","A186432-","A186433-","G186434-","A186435-","G186436-","A186437-","T186438-","G186439-","T186440-","T186441-","G186442-","T186443-","A186444-","T186445-","A186446-","A186447-","T186448-","A186449-","G186450-","A186451-","T186452-","G186453-","T186454-","T186455-","A186456-","A186457-","G186458-","A186459-","A186460-","C186461-","A186462-","A186463-","T186464-","C186465-","T186466-","T186467-","G186468-","T186469-","T186470-","A186471-","A186472-","A186473-","A186474-","A186475-","G186476-","T186477-","A186478-","C186479-","T186480-","A186481-","T186482-","T186483-","C186484-","T186485-","A186486-","T186487-","T186488-","G186489-","A186490-","T186491-","A186492-","A186493-","T186494-","T186495-","A186496-","T186497-","C186498-","T186499-","A186500-","T186501-","G186502-","T186503-","G186504-","A186505-","T186506-","A186507-","C186508-","T186509-","T186510-","T186511-","A186512-","G186513-","A186514-","T186515-","G186516-","A186517-","T186518-","T186519-","A186520-","T186521-","A186522-","T186523-","A186524-","T186525-","A186526-","C186527-","A186528-","C186529-","C186530-","T186531-","C186532-","T186533-","G186534-","T186535-","A186536-","G186537-","A186538-","A186539-","T186540-","A186541-","T186542-","A186543-","A186544-","C186545-","A186546-","A186547-","A186548-","T186549-","C186550-","C186551-","T186552-","A186553-","T186554-","G186555-","T186556-","G186557-","T186558-","T186559-","A186560-","G186561-","T186562-","A186563-","A186564-","A186565-","C186566-","G186567-","A186568-","T186569-","A186570-","C186571-","T186572-","T186573-","A186574-","T186575-","A186576-","T186577-","A186578-","A186579-","G186580-","C186581-","T186582-","A186583-","T186584-","G186585-","A186586-","C186587-","T186588-","A186589-","T186590-","C186591-","T186592-","T186593-","G186594-","A186595-","A186596-","T186597-","C186598-","A186599-","T186600-","C186601-","A186602-","G186603-","G186604-","T186605-","G186606-","T186607-","A186608-","G186609-","T186610-","T186611-","G186612-","T186613-","T186614-","C186615-","T186616-","A186617-","T186618-","C186619-","A186620-","T186621-","G186622-","T186623-","T186624-","A186625-","T186626-","G186627-","A186628-","A186629-","A186630-","T186631-","G186632-","A186633-","C186634-","T186635-","A186636-","T186637-","A186638-","A186639-","T186640-","C186641-","T186642-","C186643-","C186644-","T186645-","T186646-","G186647-","G186648-","A186649-","T186650-","A186651-","C186652-","A186653-","A186654-","A186655-","A186656-","G186657-","A186658-","C186659-","G186660-","C186661-","C186662-","A186663-","A186664-","A186665-","G186666-","A186667-","T186668-","G186669-","C186670-","T186671-","A186672-","T186673-","A186674-","G186675-","A186676-","A186677-","G186678-","A186679-","T186680-","G186681-","T186682-","G186683-","A186684-","T186685-","A186686-","G186687-","T186688-","A186689-","G186690-","C186691-","A186692-","A186693-","G186694-","T186695-","G186696-","C186697-","G186698-","G186699-","T186700-","A186701-","G186702-","C186703-","C186704-","G186705-","A186706-","A186707-","G186708-","C186709-","A186710-","T186711-","T186712-","G186713-","A186714-","A186715-","T186716-","G186717-","A186718-","C186719-","A186720-","T186721-","G186722-","T186723-","T186724-","T186725-","A186726-","A186727-","G186728-","G186729-","A186730-","A186731-","T186732-","T186733-","T186734-","G186735-","A186736-","T186737-","A186738-","A186739-","A186740-","A186741-","A186742-","C186743-","G186744-","T186745-","A186746-","A186747-","G186748-","T186749-","G186750-","C186751-","T186752-","A186753-","T186754-","T186755-","A186756-","T186757-","A186758-","A186759-","T186760-","A186761-","A186762-","A186763-","A186764-","G186765-","A186766-","A186767-","G186768-","A186769-","A186770-","G186771-","A186772-","T186773-","A186774-","A186775-","T186776-","T186777-","A186778-","T186779-","C186780-","T186781-","A186782-","A186783-","A186784-","C186785-","A186786-","G186787-","T186788-","T186789-","C186790-","G186791-","C186792-","C186793-","C186794-","G186795-","A186796-","T186797-","A186798-","T186799-","C186800-","T186801-","A186802-","C186803-","C186804-","A186805-","T186806-","A186807-","T186808-","A186809-","A186810-","T186811-","A186812-","T186813-","A186814-","T186815-","A186816-","T186817-","C186818-","A186819-","T186820-","A186821-","G186822-","G186823-","T186824-","G186825-","G186826-","C186827-","A186828-","C186829-","T186830-","A186831-","T186832-","T186833-","C186834-","T186835-","G186836-","C186837-","T186838-","A186839-","C186840-","T186841-","G186842-","T186843-","T186844-","A186845-","G186846-","T186847-","C186848-","A186849-","T186850-","T186851-","A186852-","T186853-","T186854-","T186855-","T186856-","A186857-","A186858-","T186859-","A186860-","T186861-","T186862-","G186863-","G186864-","C186865-","A186866-","A186867-","T186868-","T186869-","T186870-","A186871-","T186872-","A186873-","T186874-","A186875-","G186876-","C186877-","G186878-","C186879-","G186880-","C186881-","A186882-","A186883-","T186884-","A186885-","A186886-","A186887-","T186888-","A186889-","C186890-","A186891-","G186892-","A186893-","A186894-","C186895-","C186896-","A186897-","G186898-","G186899-","A186900-","A186901-","A186902-","T186903-","A186904-","T186905-","G186906-","A186907-","A186908-","A186909-","T186910-","A186911-","A186912-","T186913-","G186914-","A186915-","A186916-","A186917-","T186918-","A186919-","T186920-","G186921-","A186922-","C186923-","A186924-","A186925-","T186926-","A186927-","T186928-","G186929-","A186930-","G186931-","C186932-","A186933-","T186934-","T186935-","A186936-","A186937-","A186938-","T186939-","C186940-","T186941-","G186942-","A186943-","G186944-","C186945-","A186946-","T186947-","C186948-","A186949-","T186950-","G186951-","A186952-","T186953-","A186954-","G186955-","T186956-","C186957-","T186958-","T186959-","G186960-","A186961-","A186962-","A186963-","C186964-","A186965-","G186966-","T186967-","G186968-","T186969-","C186970-","T186971-","A186972-","T186973-","G186974-","G186975-","A186976-","A186977-","A186978-","T186979-","T186980-","A186981-","T186982-","T186983-","G186984-","A186985-","T186986-","A186987-","A186988-","T186989-","C186990-","G186991-","G186992-","T186993-","A186994-","C186995-","T186996-","A186997-","A186998-","T186999-","A187000-","A187001-","A187002-","A187003-","T187004-","A187005-","G187006-","T187007-","T187008-","T187009-","A187010-","A187011-","C187012-","T187013-","C187014-","T187015-","T187016-","T187017-","T187018-","A187019-","G187020-","A187021-","A187022-","C187023-","C187024-","A187025-","G187026-","T187027-","T187028-","T187029-","G187030-","G187031-","T187032-","A187033-","C187034-","T187035-","G187036-","T187037-","A187038-","A187039-","T187040-","T187041-","T187042-","C187043-","A187044-","G187045-","T187046-","T187047-","C187048-","A187049-","T187050-","T187051-","A187052-","C187053-","T187054-","C187055-","G187056-","T187057-","T187058-","G187059-","A187060-","G187061-","A187062-","A187063-","T187064-","A187065-","T187066-","T187067-","G187068-","A187069-","T187070-","G187071-","A187072-","T187073-","T187074-","T187075-","T187076-","T187077-","T187078-","T187079-","T187080-","A187081-","A187082-","A187083-","T187084-","G187085-","A187086-","G187087-","T187088-","A187089-","T187090-","C187091-","G187092-","G187093-","T187094-","A187095-","G187096-","T187097-","T187098-","A187099-","C187100-","A187101-","T187102-","A187103-","T187104-","T187105-","A187106-","C187107-","C187108-","A187109-","T187110-","A187111-","T187112-","C187113-","A187114-","T187115-","C187116-","C187117-","A187118-","T187119-","T187120-","A187121-","T187122-","A187123-","T187124-","A187125-","A187126-","T187127-","C187128-","G187129-","A187130-","T187131-","G187132-","A187133-","T187134-","G187135-","C187136-","A187137-","T187138-","G187139-","T187140-","A187141-","T187142-","T187143-","A187144-","G187145-","A187146-","A187147-","T187148-","A187149-","C187150-","T187151-","T187152-","T187153-","C187154-","C187155-","G187156-","A187157-","A187158-","T187159-","A187160-","A187161-","G187162-","T187163-","C187164-","T187165-","T187166-","C187167-","T187168-","A187169-","A187170-","A187171-","T187172-","A187173-","T187174-","T187175-","G187176-","T187177-","A187178-","T187179-","T187180-","A187181-","A187182-","T187183-","T187184-","A187185-","T187186-","G187187-","A187188-","A187189-","A187190-","A187191-","A187192-","C187193-","T187194-","A187195-","T187196-","G187197-","C187198-","T187199-","A187200-","T187201-","G187202-","T187203-","G187204-","A187205-","G187206-","T187207-","A187208-","T187209-","G187210-","A187211-","T187212-","T187213-","C187214-","A187215-","A187216-","A187217-","G187218-","A187219-","T187220-","G187221-","T187222-","T187223-","T187224-","A187225-","A187226-","T187227-","G187228-","A187229-","T187230-","A187231-","C187232-","G187233-","A187234-","T187235-","A187236-","C187237-","T187238-","A187239-","G187240-","A187241-","T187242-","T187243-","T187244-","T187245-","A187246-","T187247-","C187248-","T187249-","C187250-","T187251-","A187252-","G187253-","C187254-","G187255-","A187256-","G187257-","A187258-","T187259-","T187260-","G187261-","T187262-","T187263-","T187264-","A187265-","G187266-","A187267-","A187268-","T187269-","C187270-","A187271-","T187272-","T187273-","T187274-","A187275-","T187276-","C187277-","A187278-","T187279-","A187280-","A187281-","C187282-","T187283-","A187284-","T187285-","G187286-","T187287-","T187288-","T187289-","A187290-","A187291-","T187292-","A187293-","A187294-","A187295-","T187296-","T187297-","C187298-","A187299-","T187300-","C187301-","A187302-","A187303-","C187304-","G187305-","A187306-","A187307-","T187308-","A187309-","T187310-","C187311-","G187312-","A187313-","T187314-","A187315-","A187316-","A187317-","G187318-","A187319-","C187320-","C187321-","T187322-","C187323-","T187324-","T187325-","G187326-","T187327-","A187328-","A187329-","T187330-","T187331-","C187332-","G187333-","A187334-","G187335-","T187336-","A187337-","T187338-","A187339-","G187340-","G187341-","A187342-","A187343-","G187344-","T187345-","A187346-","G187347-","T187348-","A187349-","T187350-","T187351-","A187352-","C187353-","C187354-","A187355-","T187356-","A187357-","T187358-","C187359-","A187360-","A187361-","C187362-","T187363-","T187364-","C187365-","C187366-","G187367-","A187368-","G187369-","T187370-","T187371-","A187372-","A187373-","C187374-","A187375-","A187376-","T187377-","T187378-","A187379-","C187380-","T187381-","C187382-","T187383-","A187384-","A187385-","A187386-","A187387-","C187388-","A187389-","T187390-","G187391-","A187392-","G187393-","G187394-","A187395-","T187396-","T187397-","G187398-","T187399-","A187400-","C187401-","T187402-","C187403-","C187404-","T187405-","G187406-","T187407-","C187408-","T187409-","T187410-","T187411-","A187412-","T187413-","T187414-","G187415-","G187416-","A187417-","G187418-","A187419-","T187420-","C187421-","A187422-","C187423-","T187424-","A187425-","T187426-","T187427-","T187428-","A187429-","G187430-","T187431-","C187432-","G187433-","T187434-","T187435-","G187436-","A187437-","T187438-","A187439-","A187440-","A187441-","C187442-","T187443-","A187444-","G187445-","T187446-","A187447-","A187448-","C187449-","C187450-","T187451-","C187452-","A187453-","G187454-","G187455-","T187456-","T187457-","T187458-","C187459-","T187460-","T187461-","T187462-","A187463-","C187464-","A187465-","A187466-","A187467-","C187468-","G187469-","A187470-","T187471-","A187472-","A187473-","A187474-","G187475-","T187476-","A187477-","C187478-","A187479-","A187480-","C187481-","A187482-","T187483-","C187484-","A187485-","A187486-","G187487-","A187488-","C187489-","C187490-","T187491-","C187492-","A187493-","C187494-","A187495-","A187496-","C187497-","A187498-","C187499-","A187500-","G187501-","T187502-","G187503-","C187504-","A187505-","A187506-","G187507-","A187508-","T187509-","T187510-","A187511-","A187512-","T187513-","C187514-","T187515-","A187516-","G187517-","A187518-","A187519-","A187520-","T187521-","C187522-","A187523-","A187524-","A187525-","T187526-","G187527-","T187528-","A187529-","A187530-","T187531-","T187532-","C187533-","T187534-","G187535-","G187536-","A187537-","G187538-","G187539-","A187540-","G187541-","A187542-","A187543-","T187544-","C187545-","T187546-","A187547-","G187548-","A187549-","C187550-","A187551-","A187552-","C187553-","T187554-","A187555-","A187556-","C187557-","A187558-","C187559-","C187560-","C187561-","A187562-","C187563-","G187564-","G187565-","C187566-","G187567-","A187568-","A187569-","G187570-","T187571-","A187572-","T187573-","A187574-","C187575-","T187576-","T187577-","T187578-","A187579-","T187580-","G187581-","C187582-","C187583-","T187584-","C187585-","A187586-","T187587-","T187588-","C187589-","A187590-","G187591-","A187592-","A187593-","A187594-","C187595-","G187596-","G187597-","T187598-","A187599-","A187600-","C187601-","T187602-","G187603-","T187604-","A187605-","G187606-","T187607-","A187608-","G187609-","G187610-","A187611-","G187612-","A187613-","C187614-","T187615-","G187616-","T187617-","C187618-","T187619-","C187620-","T187621-","C187622-","T187623-","A187624-","A187625-","T187626-","C187627-","T187628-","C187629-","G187630-","A187631-","T187632-","G187633-","T187634-","A187635-","T187636-","A187637-","T187638-","A187639-","T187640-","A187641-","A187642-","T187643-","A187644-","T187645-","A187646-","T187647-","A187648-","C187649-","C187650-","A187651-","A187652-","T187653-","A187654-","C187655-","G187656-","G187657-","A187658-","C187659-","G187660-","C187661-","G187662-","A187663-","T187664-","A187665-","T187666-","A187667-","T187668-","T187669-","C187670-","C187671-","G187672-","A187673-","C187674-","A187675-","T187676-","G187677-","A187678-","A187679-","T187680-","G187681-","G187682-","C187683-","G187684-","T187685-","C187686-","G187687-","C187688-","T187689-","T187690-","A187691-","T187692-","C187693-","A187694-","T187695-","A187696-","T187697-","G187698-","T187699-","T187700-","A187701-","T187702-","A187703-","T187704-","C187705-","C187706-","T187707-","A187708-","A187709-","A187710-","T187711-","G187712-","T187713-","T187714-","G187715-","A187716-","T187717-","C187718-","A187719-","T187720-","A187721-","T187722-","T187723-","C187724-","C187725-","A187726-","C187727-","A187728-","A187729-","A187730-","T187731-","G187732-","A187733-","T187734-","T187735-","G187736-","T187737-","G187738-","A187739-","A187740-","C187741-","G187742-","A187743-","G187744-","A187745-","T187746-","T187747-","A187748-","A187749-","A187750-","T187751-","C187752-","A187753-","T187754-","C187755-","T187756-","A187757-","A187758-","C187759-","A187760-","A187761-","A187762-","T187763-","A187764-","A187765-","T187766-","T187767-","A187768-","G187769-","T187770-","T187771-","T187772-","T187773-","T187774-","T187775-","A187776-","T187777-","G187778-","A187779-","C187780-","A187781-","T187782-","T187783-","A187784-","A187785-","C187786-","A187787-","T187788-","A187789-","T187790-","A187791-","A187792-","T187793-","A187794-","A187795-","A187796-","T187797-","A187798-","A187799-","A187800-","T187801-","T187802-","A187803-","A187804-","T187805-","C187806-","A187807-","T187808-","T187809-","A187810-","T187811-","T187812-","G187813-","A187814-","C187815-","T187816-","T187817-","A187818-","A187819-","C187820-","G187821-","A187822-","T187823-","G187824-","A187825-","C187826-","G187827-","A187828-","A187829-","A187830-","G187831-","T187832-","T187833-","A187834-","T187835-","C187836-","A187837-","T187838-","T187839-","A187840-","T187841-","C187842-","T187843-","T187844-","A187845-","G187846-","G187847-","A187848-","T187849-","T187850-","C187851-","T187852-","T187853-","G187854-","A187855-","T187856-","T187857-","A187858-","T187859-","T187860-","A187861-","A187862-","T187863-","A187864-","C187865-","A187866-","A187867-","A187868-","T187869-","T187870-","C187871-","G187872-","T187873-","T187874-","G187875-","T187876-","G187877-","T187878-","C187879-","T187880-","A187881-","T187882-","G187883-","A187884-","A187885-","A187886-","T187887-","G187888-","T187889-","G187890-","A187891-","A187892-","C187893-","A187894-","A187895-","G187896-","G187897-","T187898-","G187899-","T187900-","C187901-","T187902-","C187903-","A187904-","T187905-","A187906-","T187907-","T187908-","A187909-","T187910-","A187911-","A187912-","T187913-","G187914-","C187915-","A187916-","C187917-","A187918-","A187919-","G187920-","A187921-","A187922-","T187923-","T187924-","A187925-","A187926-","A187927-","G187928-","T187929-","G187930-","T187931-","T187932-","G187933-","T187934-","A187935-","A187936-","A187937-","C187938-","T187939-","A187940-","T187941-","C187942-","T187943-","A187944-","G187945-","C187946-","C187947-","A187948-","G187949-","G187950-","A187951-","A187952-","C187953-","A187954-","T187955-","A187956-","T187957-","T187958-","C187959-","A187960-","G187961-","A187962-","T187963-","T187964-","A187965-","T187966-","C187967-","G187968-","A187969-","T187970-","G187971-","T187972-","G187973-","A187974-","T187975-","A187976-","A187977-","A187978-","T187979-","A187980-","C187981-","A187982-","G187983-","C187984-","G187985-","A187986-","T187987-","A187988-","C187989-","C187990-","A187991-","T187992-","C187993-","T187994-","G187995-","T187996-","G187997-","G187998-","A187999-","C188000-","A188001-","T188002-","T188003-","G188004-","T188005-","C188006-","C188007-","A188008-","A188009-","G188010-","T188011-","G188012-","A188013-","C188014-","A188015-","C188016-","A188017-","T188018-","T188019-","C188020-","A188021-","C188022-","G188023-","T188024-","C188025-","A188026-","A188027-","T188028-","A188029-","T188030-","A188031-","T188032-","A188033-","A188034-","T188035-","C188036-","G188037-","T188038-","T188039-","C188040-","T188041-","C188042-","C188043-","T188044-","C188045-","G188046-","G188047-","T188048-","G188049-","T188050-","C188051-","A188052-","T188053-","A188054-","G188055-","T188056-","T188057-","G188058-","T188059-","A188060-","G188061-","A188062-","G188063-","G188064-","T188065-","C188066-","A188067-","C188068-","A188069-","C188070-","C188071-","T188072-","T188073-","G188074-","T188075-","A188076-","C188077-","A188078-","C188079-","C188080-","T188081-","A188082-","C188083-","C188084-","A188085-","C188086-","A188087-","A188088-","A188089-","T188090-","A188091-","G188092-","A188093-","A188094-","T188095-","A188096-","T188097-","G188098-","T188099-","C188100-","A188101-","T188102-","T188103-","G188104-","T188105-","G188106-","A188107-","C188108-","T188109-","C188110-","G188111-","A188112-","A188113-","T188114-","A188115-","G188116-","T188117-","T188118-","A188119-","T188120-","C188121-","G188122-","T188123-","C188124-","T188125-","C188126-","C188127-","T188128-","T188129-","A188130-","A188131-","A188132-","G188133-","C188134-","T188135-","T188136-","C188137-","T188138-","G188139-","A188140-","T188141-","G188142-","G188143-","T188144-","A188145-","A188146-","C188147-","T188148-","G188149-","T188150-","G188151-","T188152-","T188153-","A188154-","C188155-","A188156-","T188157-","G188158-","T188159-","G188160-","C188161-","T188162-","C188163-","C188164-","T188165-","A188166-","A188167-","A188168-","A188169-","C188170-","A188171-","A188172-","A188173-","A188174-","T188175-","A188176-","T188177-","G188178-","G188179-","T188180-","C188181-","G188182-","T188183-","G188184-","T188185-","G188186-","T188187-","A188188-","C188189-","G188190-","G188191-","A188192-","A188193-","A188194-","G188195-","A188196-","A188197-","A188198-","G188199-","G188200-","A188201-","G188202-","A188203-","A188204-","A188205-","A188206-","T188207-","G188208-","A188209-","T188210-","A188211-","T188212-","G188213-","G188214-","A188215-","A188216-","T188217-","A188218-","C188219-","C188220-","A188221-","T188222-","T188223-","T188224-","G188225-","T188226-","A188227-","A188228-","G188229-","A188230-","A188231-","A188232-","T188233-","G188234-","T188235-","C188236-","G188237-","G188238-","A188239-","A188240-","G188241-","G188242-","G188243-","T188244-","A188245-","C188246-","T188247-","T188248-","A188249-","T188250-","T188251-","C188252-","A188253-","G188254-","A188255-","T188256-","A188257-","T188258-","T188259-","G188260-","T188261-","A188262-","T188263-","C188264-","T188265-","G188266-","A188267-","C188268-","T188269-","C188270-","T188271-","G188272-","A188273-","T188274-","C188275-","A188276-","A188277-","T188278-","G188279-","T188280-","A188281-","A188282-","A188283-","C188284-","C188285-","T188286-","A188287-","T188288-","G188289-","A188290-","C188291-","A188292-","A188293-","G188294-","A188295-","T188296-","A188297-","A188298-","G188299-","A188300-","C188301-","T188302-","T188303-","A188304-","C188305-","T188306-","C188307-","G188308-","C188309-","A188310-","T188311-","C188312-","T188313-","A188314-","C188315-","T188316-","G188317-","G188318-","A188319-","T188320-","A188321-","G188322-","A188323-","C188324-","A188325-","T188326-","A188327-","A188328-","A188329-","T188330-","A188331-","T188332-","C188333-","C188334-","T188335-","C188336-","C188337-","T188338-","C188339-","G188340-","T188341-","A188342-","A188343-","T188344-","A188345-","A188346-","T188347-","G188348-","A188349-","A188350-","A188351-","T188352-","A188353-","T188354-","A188355-","A188356-","T188357-","A188358-","T188359-","A188360-","C188361-","A188362-","C188363-","T188364-","A188365-","A188366-","T188367-","T188368-","A188369-","T188370-","T188371-","A188372-","A188373-","T188374-","A188375-","T188376-","C188377-","A188378-","A188379-","T188380-","C188381-","G188382-","A188383-","G188384-","T188385-","A188386-","T188387-","T188388-","A188389-","A188390-","C188391-","A188392-","T188393-","A188394-","T188395-","A188396-","A188397-","G188398-","T188399-","T188400-","A188401-","T188402-","T188403-","T188404-","T188405-","T188406-","A188407-","A188408-","A188409-","C188410-","C188411-","C188412-","C188413-","T188414-","T188415-","T188416-","T188417-","G188418-","G188419-","G188420-","T188421-","T188422-","C188423-","C188424-","G188425-","T188426-","C188427-","C188428-","T188429-","A188430-","A188431-","A188432-","C188433-","G188434-","G188435-","C188436-","G188437-","T188438-","T188439-","T188440-","C188441-","G188442-","G188443-","T188444-","C188445-","T188446-","G188447-","T188448-","G188449-","T188450-","C188451-","G188452-","C188453-","C188454-","A188455-","C188456-","C188457-","A188458-","T188459-","G188460-","G188461-","T188462-","C188463-","A188464-","C188465-","A188466-","C188467-","C188468-","G188469-","A188470-","G188471-","C188472-","C188473-","T188474-","C188475-","T188476-","G188477-","C188478-","G188479-","T188480-","G188481-","C188482-","T188483-","C188484-","C188485-","T188486-","C188487-","C188488-","A188489-","T188490-","C188491-","G188492-","A188493-","G188494-","G188495-","A188496-","C188497-","G188498-","A188499-","C188500-","T188501-","T188502-","C188503-","A188504-","A188505-","C188506-","T188507-","A188508-","T188509-","G188510-","A188511-","C188512-","A188513-","G188514-","C188515-","T188516-","C188517-","G188518-","G188519-","T188520-","G188521-","G188522-","C188523-","G188524-","T188525-","C188526-","T188527-","G188528-","C188529-","C188530-","A188531-","G188532-","C188533-","G188534-","T188535-","G188536-","T188537-","A188538-","C188539-","A188540-","T188541-","A188542-","C188543-","G188544-","A188545-","A188546-","T188547-","G188548-","G188549-","C188550-","A188551-","T188552-","T188553-","T188554-","C188555-","T188556-","A188557-","A188558-","G188559-","A188560-","A188561-","A188562-","A188563-","G188564-","T188565-","C188566-","T188567-","A188568-","C188569-","G188570-","G188571-","T188572-","A188573-","T188574-","C188575-","C188576-","T188577-","T188578-","T188579-","C188580-","T188581-","A188582-","C188583-","A188584-","A188585-","T188586-","T188587-","T188588-","C188589-","C188590-","T188591-","T188592-","T188593-","A188594-","A188595-","C188596-","A188597-","A188598-","C188599-","G188600-","G188601-","C188602-","A188603-","A188604-","C188605-","A188606-","G188607-","C188608-","T188609-","G188610-","C188611-","A188612-","G188613-","T188614-","A188615-","T188616-","T188617-","T188618-","T188619-","T188620-","A188621-","T188622-","A188623-","C188624-","T188625-","T188626-","T188627-","G188628-","A188629-","A188630-","T188631-","G188632-","C188633-","A188634-","T188635-","C188636-","G188637-","G188638-","A188639-","C188640-","A188641-","T188642-","T188643-","T188644-","A188645-","T188646-","A188647-","C188648-","A188649-","A188650-","G188651-","G188652-","G188653-","A188654-","G188655-","T188656-","C188657-","C188658-","T188659-","G188660-","T188661-","T188662-","C188663-","T188664-","A188665-","A188666-","T188667-","A188668-","T188669-","T188670-","G188671-","G188672-","C188673-","A188674-","T188675-","C188676-","A188677-","A188678-","T188679-","G188680-","T188681-","T188682-","C188683-","G188684-","G188685-","A188686-","T188687-","C188688-","T188689-","A188690-","T188691-","A188692-","G188693-","G188694-","C188695-","T188696-","T188697-","G188698-","A188699-","T188700-","T188701-","T188702-","T188703-","C188704-","G188705-","C188706-","A188707-","T188708-","T188709-","G188710-","A188711-","C188712-","T188713-","T188714-","T188715-","A188716-","C188717-","A188718-","C188719-","A188720-","G188721-","A188722-","C188723-","A188724-","T188725-","G188726-","A188727-","A188728-","C188729-","A188730-","T188731-","C188732-","C188733-","C188734-","C188735-","T188736-","G188737-","A188738-","A188739-","T188740-","C188741-","T188742-","G188743-","T188744-","A188745-","C188746-","A188747-","T188748-","A188749-","C188750-","T188751-","T188752-","T188753-","G188754-","T188755-","G188756-","G188757-","A188758-","T188759-","T188760-","T188761-","A188762-","C188763-","A188764-","C188765-","T188766-","G188767-","T188768-","T188769-","A188770-","G188771-","A188772-","A188773-","T188774-","C188775-","T188776-","C188777-","T188778-","A188779-","A188780-","C188781-","G188782-","C188783-","T188784-","G188785-","G188786-","C188787-","C188788-","T188789-","C188790-","T188791-","G188792-","T188793-","T188794-","G188795-","T188796-","T188797-","A188798-","C188799-","T188800-","T188801-","T188802-","C188803-","T188804-","A188805-","T188806-","G188807-","A188808-","T188809-","G188810-","C188811-","A188812-","C188813-","G188814-","T188815-","A188816-","T188817-","C188818-","G188819-","T188820-","T188821-","A188822-","T188823-","G188824-","C188825-","A188826-","A188827-","G188828-","C188829-","T188830-","T188831-","T188832-","C188833-","A188834-","T188835-","G188836-","T188837-","T188838-","G188839-","A188840-","C188841-","T188842-","A188843-","C188844-","T188845-","G188846-","C188847-","A188848-","G188849-","T188850-","G188851-","T188852-","T188853-","T188854-","C188855-","T188856-","T188857-","G188858-","C188859-","T188860-","C188861-","T188862-","G188863-","A188864-","C188865-","T188866-","A188867-","C188868-","A188869-","T188870-","A188871-","T188872-","A188873-","C188874-","T188875-","C188876-","T188877-","A188878-","C188879-","A188880-","A188881-","T188882-","C188883-","A188884-","A188885-","A188886-","G188887-","A188888-","G188889-","A188890-","G188891-","A188892-","T188893-","T188894-","T188895-","C188896-","A188897-","G188898-","T188899-","A188900-","A188901-","A188902-","C188903-","T188904-","T188905-","G188906-","T188907-","A188908-","A188909-","C188910-","A188911-","G188912-","G188913-","A188914-","T188915-","T188916-","G188917-","T188918-","T188919-","T188920-","G188921-","C188922-","T188923-","G188924-","C188925-","T188926-","T188927-","T188928-","C188929-","T188930-","G188931-","G188932-","A188933-","T188934-","T188935-","T188936-","T188937-","A188938-","A188939-","T188940-","T188941-","T188942-","T188943-","G188944-","T188945-","C188946-","A188947-","G188948-","G188949-","A188950-","G188951-","T188952-","C188953-","T188954-","T188955-","G188956-","A188957-","G188958-","G188959-","A188960-","T188961-","A188962-","A188963-","A188964-","G188965-","T188966-","T188967-","T188968-","A188969-","A188970-","A188971-","A188972-","T188973-","A188974-","G188975-","A188976-","A188977-","T188978-","T188979-","A188980-","A188981-","T188982-","A188983-","A188984-","A188985-","G188986-","A188987-","A188988-","C188989-","A188990-","T188991-","A188992-","T188993-","A188994-","G188995-","G188996-","T188997-","C188998-","A188999-","T189000-","T189001-","T189002-","T189003-","T189004-","T189005-","A189006-","A189007-","A189008-","C189009-","A189010-","T189011-","G189012-","G189013-","A189014-","T189015-","A189016-","G189017-","A189018-","A189019-","A189020-","C189021-","C189022-","A189023-","A189024-","G189025-","G189026-","T189027-","T189028-","G189029-","T189030-","T189031-","A189032-","G189033-","T189034-","T189035-","A189036-","A189037-","T189038-","A189039-","A189040-","T189041-","A189042-","T189043-","A189044-","C189045-","A189046-","A189047-","G189048-","A189049-","T189050-","A189051-","T189052-","T189053-","T189054-","T189055-","T189056-","T189057-","C189058-","T189059-","C189060-","A189061-","C189062-","T189063-","C189064-","T189065-","G189066-","A189067-","T189068-","C189069-","C189070-","A189071-","T189072-","G189073-","T189074-","A189075-","A189076-","A189077-","C189078-","C189079-","A189080-","A189081-","G189082-","G189083-","A189084-","C189085-","G189086-","A189087-","G189088-","A189089-","G189090-","A189091-","C189092-","A189093-","C189094-","T189095-","C189096-","T189097-","C189098-","A189099-","T189100-","T189101-","C189102-","C189103-","T189104-","C189105-","A189106-","T189107-","T189108-","C189109-","A189110-","C189111-","G189112-","A189113-","C189114-","A189115-","C189116-","C189117-","A189118-","T189119-","T189120-","A189121-","A189122-","A189123-","A189124-","A189125-","T189126-","G189127-","G189128-","A189129-","A189130-","A189131-","T189132-","T189133-","A189134-","A189135-","A189136-","G189137-","C189138-","C189139-","C189140-","T189141-","C189142-","T189143-","A189144-","T189145-","T189146-","A189147-","A189148-","G189149-","C189150-","A189151-","C189152-","A189153-","G189154-","A189155-","C189156-","G189157-","G189158-","C189159-","T189160-","A189161-","C189162-","A189163-","G189164-","G189165-","T189166-","C189167-","T189168-","A189169-","C189170-","C189171-","A189172-","T189173-","C189174-","A189175-","G189176-","G189177-","T189178-","T189179-","A189180-","C189181-","C189182-","T189183-","T189184-","C189185-","G189186-","T189187-","C189188-","T189189-","A189190-","C189191-","C189192-","T189193-","T189194-","C189195-","A189196-","C189197-","A189198-","A189199-","T189200-","G189201-","G189202-","C189203-","C189204-","T189205-","C189206-","T189207-","C189208-","C189209-","T189210-","T189211-","G189212-","T189213-","G189214-","C189215-","C189216-","C189217-","A189218-","G189219-","T189220-","T189221-","C189222-","A189223-","G189224-","T189225-","C189226-","C189227-","C189228-","T189229-","G189230-","T189231-","C189232-","A189233-","T189234-","T189235-","G189236-","C189237-","C189238-","A189239-","C189240-","G189241-","C189242-","T189243-","A189244-","C189245-","T189246-","A189247-","A189248-","G189249-","G189250-","A189251-","C189252-","T189253-","C189254-","C189255-","C189256-","T189257-","G189258-","A189259-","A189260-","T189261-","A189262-","C189263-","C189264-","G189265-","T189266-","G189267-","A189268-","C189269-","T189270-","G189271-","A189272-","C189273-","G189274-","T189275-","C189276-","A189277-","G189278-","A189279-","C189280-","A189281-","T189282-","T189283-","G189284-","T189285-","C189286-","T189287-","G189288-","A189289-","C189290-","T189291-","G189292-","A189293-","A189294-","T189295-","A189296-","C189297-","A189298-","T189299-","C189300-","C189301-","T189302-","G189303-","T189304-","G189305-","G189306-","G189307-","T189308-","T189309-","T189310-","C189311-","T189312-","C189313-","A189314-","T189315-","A189316-","G189317-","A189318-","T189319-","G189320-","G189321-","A189322-","C189323-","C189324-","C189325-","A189326-","T189327-","A189328-","G189329-","A189330-","G189331-","A189332-","A189333-","A189334-","G189335-","C189336-","G189337-","C189338-","A189339-","G189340-","G189341-","G189342-","C189343-","C189344-","T189345-","C189346-","T189347-","C189348-","T189349-","A189350-","C189351-","A189352-","G189353-","G189354-","C189355-","T189356-","T189357-","C189358-","T189359-","C189360-","A189361-","T189362-","C189363-","T189364-","C189365-","T189366-","T189367-","T189368-","C189369-","A189370-","G189371-","A189372-","A189373-","T189374-","T189375-","G189376-","A189377-","T189378-","G189379-","C189380-","A189381-","A189382-","T189383-","G189384-","G189385-","A189386-","G189387-","C189388-","T189389-","A189390-","T189391-","T189392-","T189393-","G189394-","G189395-","T189396-","A189397-","G189398-","C189399-","G189400-","A189401-","G189402-","T189403-","T189404-","G189405-","A189406-","A189407-","G189408-","G189409-","A189410-","G189411-","T189412-","T189413-","C189414-","T189415-","C189416-","G189417-","A189418-","A189419-","T189420-","T189421-","C189422-","A189423-","C189424-","T189425-","T189426-","C189427-","C189428-","G189429-","T189430-","G189431-","G189432-","G189433-","A189434-","C189435-","A189436-","A189437-","T189438-","A189439-","T189440-","C189441-","G189442-","A189443-","C189444-","A189445-","A189446-","T189447-","T189448-","G189449-","C189450-","G189451-","T189452-","G189453-","G189454-","A189455-","G189456-","A189457-","T189458-","C189459-","A189460-","T189461-","T189462-","A189463-","A189464-","A189465-","T189466-","G189467-","T189468-","T189469-","T189470-","C189471-","A189472-","T189473-","C189474-","A189475-","G189476-","A189477-","A189478-","A189479-","T189480-","G189481-","A189482-","C189483-","T189484-","C189485-","C189486-","A189487-","T189488-","G189489-","A189490-","A189491-","A189492-","A189493-","C189494-","C189495-","G189496-","C189497-","C189498-","A189499-","A189500-","A189501-","G189502-","A189503-","A189504-","C189505-","T189506-","T189507-","T189508-","G189509-","T189510-","G189511-","C189512-","A189513-","A189514-","T189515-","A189516-","A189517-","T189518-","T189519-","G189520-","G189521-","A189522-","C189523-","T189524-","T189525-","T189526-","G189527-","T189528-","A189529-","C189530-","T189531-","C189532-","A189533-","A189534-","T189535-","C189536-","A189537-","G189538-","C189539-","T189540-","A189541-","T189542-","T189543-","G189544-","T189545-","C189546-","A189547-","C189548-","T189549-","G189550-","G189551-","A189552-","A189553-","G189554-","A189555-","G189556-","T189557-","C189558-","T189559-","T189560-","C189561-","A189562-","A189563-","T189564-","G189565-","A189566-","T189567-","A189568-","A189569-","G189570-","T189571-","A189572-","T189573-","A189574-","T189575-","C189576-","G189577-","A189578-","C189579-","A189580-","T189581-","A189582-","C189583-","T189584-","A189585-","C189586-","T189587-","T189588-","A189589-","T189590-","G189591-","C189592-","T189593-","G189594-","C189595-","G189596-","A189597-","A189598-","A189599-","G189600-","A189601-","T189602-","T189603-","C189604-","T189605-","G189606-","A189607-","A189608-","C189609-","G189610-","A189611-","G189612-","A189613-","A189614-","C189615-","G189616-","A189617-","C189618-","T189619-","A189620-","T189621-","C189622-","T189623-","C189624-","A189625-","C189626-","C189627-","C189628-","T189629-","C189630-","T189631-","T189632-","G189633-","G189634-","A189635-","T189636-","C189637-","A189638-","T189639-","A189640-","T189641-","C189642-","C189643-","T189644-","C189645-","A189646-","C189647-","T189648-","G189649-","C189650-","T189651-","A189652-","A189653-","A189654-","T189655-","A189656-","C189657-","T189658-","A189659-","A189660-","A189661-","T189662-","C189663-","T189664-","C189665-","C189666-","T189667-","T189668-","C189669-","A189670-","T189671-","G189672-","C189673-","T189674-","C189675-","T189676-","C189677-","T189678-","C189679-","A189680-","C189681-","T189682-","A189683-","A189684-","T189685-","A189686-","C189687-","T189688-","C189689-","T189690-","T189691-","A189692-","C189693-","T189694-","C189695-","A189696-","C189697-","T189698-","A189699-","C189700-","A189701-","C189702-","T189703-","T189704-","T189705-","T189706-","T189707-","A189708-","T189709-","C189710-","A189711-","T189712-","C189713-","T189714-","T189715-","A189716-","T189717-","G189718-","A189719-","T189720-","G189721-","A189722-","A189723-","T189724-","G189725-","A189726-","T189727-","T189728-","G189729-","C189730-","C189731-","T189732-","T189733-","C189734-","A189735-","T189736-","C189737-","A189738-","T189739-","T189740-","T189741-","T189742-","T189743-","T189744-","C189745-","G189746-","T189747-","G189748-","G189749-","A189750-","A189751-","T189752-","A189753-","T189754-","A189755-","A189756-","T189757-","A189758-","T189759-","A189760-","G189761-","G189762-","A189763-","A189764-","T189765-","A189766-","A189767-","T189768-","T189769-","A189770-","G189771-","C189772-","A189773-","C189774-","C189775-","A189776-","G189777-","A189778-","A189779-","T189780-","A189781-","G189782-","C189783-","T189784-","A189785-","T189786-","G189787-","G189788-","A189789-","T189790-","A189791-","T189792-","C189793-","T189794-","C189795-","G189796-","T189797-","T189798-","A189799-","A189800-","G189801-","A189802-","A189803-","T189804-","A189805-","T189806-","T189807-","C189808-","T189809-","C189810-","T189811-","A189812-","T189813-","A189814-","A189815-","G189816-","A189817-","G189818-","A189819-","C189820-","A189821-","T189822-","A189823-","A189824-","T189825-","G189826-","T189827-","A189828-","G189829-","A189830-","C189831-","A189832-","T189833-","A189834-","G189835-","T189836-","T189837-","A189838-","T189839-","T189840-","A189841-","T189842-","A189843-","T189844-","C189845-","C189846-","T189847-","T189848-","C189849-","T189850-","T189851-","A189852-","G189853-","A189854-","T189855-","A189856-","A189857-","G189858-","T189859-","G189860-","T189861-","T189862-","A189863-","C189864-","G189865-","C189866-","T189867-","A189868-","C189869-","T189870-","G189871-","G189872-","A189873-","A189874-","A189875-","G189876-","T189877-","T189878-","T189879-","C189880-","C189881-","A189882-","T189883-","C189884-","G189885-","T189886-","T189887-","A189888-","T189889-","T189890-","A189891-","T189892-","T189893-","A189894-","C189895-","A189896-","T189897-","G189898-","A189899-","A189900-","G189901-","A189902-","T189903-","G189904-","A189905-","T189906-","A189907-","T189908-","A189909-","A189910-","T189911-","T189912-","A189913-","A189914-","A189915-","C189916-","C189917-","A189918-","A189919-","C189920-","A189921-","T189922-","T189923-","G189924-","A189925-","G189926-","A189927-","T189928-","T189929-","G189930-","G189931-","C189932-","T189933-","C189934-","T189935-","T189936-","A189937-","T189938-","G189939-","T189940-","T189941-","A189942-","G189943-","C189944-","T189945-","G189946-","G189947-","A189948-","T189949-","T189950-","G189951-","A189952-","A189953-","T189954-","T189955-","A189956-","C189957-","T189958-","G189959-","T189960-","A189961-","A189962-","T189963-","A189964-","A189965-","A189966-","T189967-","G189968-","C189969-","A189970-","T189971-","C189972-","G189973-","A189974-","G189975-","T189976-","A189977-","T189978-","A189979-","G189980-","A189981-","G189982-","G189983-","G189984-","A189985-","T189986-","A189987-","T189988-","A189989-","G189990-","C189991-","A189992-","A189993-","T189994-","T189995-","C189996-","T189997-","C189998-","G189999-","A190000-","T190001-","A190002-","A190003-","T190004-","A190005-","G190006-","T190007-","C190008-","A190009-","T190010-","G190011-","C190012-","A190013-","A190014-","T190015-","A190016-","T190017-","T190018-","T190019-","G190020-","A190021-","A190022-","T190023-","G190024-","A190025-","G190026-","A190027-","C190028-","T190029-","G190030-","A190031-","T190032-","A190033-","A190034-","T190035-","T190036-","T190037-","A190038-","G190039-","G190040-","T190041-","A190042-","A190043-","T190044-","A190045-","C190046-","A190047-","G190048-","T190049-","A190050-","C190051-","T190052-","A190053-","C190054-","A190055-","C190056-","A190057-","C190058-","A190059-","T190060-","A190061-","T190062-","C190063-","T190064-","T190065-","T190066-","C190067-","T190068-","A190069-","G190070-","A190071-","T190072-","T190073-","A190074-","T190075-","A190076-","T190077-","A190078-","T190079-","C190080-","G190081-","T190082-","T190083-","A190084-","A190085-","A190086-","A190087-","A190088-","T190089-","C190090-","T190091-","G190092-","T190093-","A190094-","A190095-","G190096-","A190097-","T190098-","G190099-","T190100-","A190101-","T190102-","A190103-","T190104-","T190105-","T190106-","C190107-","T190108-","C190109-","A190110-","T190111-","A190112-","A190113-","G190114-","T190115-","A190116-","T190117-","C190118-","C190119-","A190120-","C190121-","T190122-","G190123-","T190124-","G190125-","T190126-","A190127-","A190128-","T190129-","A190130-","T190131-","T190132-","A190133-","T190134-","T190135-","A190136-","A190137-","T190138-","G190139-","G190140-","A190141-","T190142-","A190143-","T190144-","A190145-","T190146-","A190147-","G190148-","A190149-","T190150-","A190151-","A190152-","C190153-","G190154-","C190155-","A190156-","A190157-","T190158-","A190159-","G190160-","G190161-","G190162-","A190163-","C190164-","T190165-","A190166-","A190167-","T190168-","A190169-","G190170-","T190171-","A190172-","T190173-","T190174-","G190175-","T190176-","A190177-","A190178-","A190179-","A190180-","G190181-","A190182-","T190183-","A190184-","T190185-","A190186-","A190187-","T190188-","C190189-","G190190-","A190191-","C190192-","T190193-","A190194-","T190195-","T190196-","T190197-","A190198-","C190199-","G190200-","T190201-","A190202-","C190203-","A190204-","T190205-","A190206-","T190207-","C190208-","C190209-","A190210-","G190211-","A190212-","T190213-","A190214-","T190215-","C190216-","T190217-","A190218-","T190219-","A190220-","T190221-","T190222-","C190223-","C190224-","T190225-","A190226-","C190227-","T190228-","A190229-","G190230-","T190231-","T190232-","T190233-","G190234-","C190235-","T190236-","G190237-","C190238-","G190239-","T190240-","A190241-","G190242-","T190243-","T190244-","G190245-","C190246-","A190247-","T190248-","C190249-","A190250-","T190251-","T190252-","G190253-","A190254-","T190255-","A190256-","T190257-","G190258-","C190259-","A190260-","T190261-","G190262-","A190263-","T190264-","T190265-","T190266-","A190267-","T190268-","C190269-","A190270-","G190271-","G190272-","A190273-","T190274-","T190275-","C190276-","A190277-","G190278-","A190279-","G190280-","A190281-","T190282-","G190283-","A190284-","A190285-","T190286-","T190287-","A190288-","C190289-","T190290-","A190291-","A190292-","G190293-","T190294-","A190295-","A190296-","A190297-","C190298-","T190299-","A190300-","C190301-","A190302-","A190303-","T190304-","C190305-","C190306-","C190307-","A190308-","C190309-","A190310-","A190311-","T190312-","A190313-","A190314-","G190315-","T190316-","A190317-","A190318-","G190319-","A190320-","A190321-","T190322-","C190323-","A190324-","A190325-","A190326-","T190327-","A190328-","T190329-","C190330-","A190331-","A190332-","A190333-","A190334-","A190335-","C190336-","T190337-","C190338-","A190339-","C190340-","T190341-","T190342-","T190343-","T190344-","G190345-","A190346-","T190347-","T190348-","T190349-","T190350-","T190351-","C190352-","T190353-","A190354-","G190355-","T190356-","C190357-","T190358-","T190359-","A190360-","A190361-","G190362-","T190363-","A190364-","A190365-","T190366-","A190367-","C190368-","A190369-","T190370-","A190371-","T190372-","A190373-","T190374-","T190375-","T190376-","A190377-","T190378-","T190379-","A190380-","A190381-","T190382-","A190383-","G190384-","A190385-","C190386-","C190387-","T190388-","A190389-","T190390-","G190391-","A190392-","A190393-","A190394-","T190395-","A190396-","A190397-","A190398-","A190399-","A190400-","A190401-","A190402-","G190403-","G190404-","T190405-","A190406-","A190407-","C190408-","A190409-","A190410-","T190411-","G190412-","G190413-","A190414-","T190415-","T190416-","C190417-","G190418-","C190419-","G190420-","T190421-","A190422-","T190423-","A190424-","G190425-","C190426-","T190427-","A190428-","T190429-","T190430-","T190431-","A190432-","C190433-","G190434-","T190435-","A190436-","T190437-","T190438-","A190439-","G190440-","T190441-","A190442-","T190443-","C190444-","G190445-","G190446-","C190447-","A190448-","T190449-","C190450-","T190451-","C190452-","T190453-","T190454-","T190455-","T190456-","G190457-","T190458-","A190459-","T190460-","C190461-","T190462-","T190463-","G190464-","T190465-","T190466-","A190467-","A190468-","T190469-","T190470-","G190471-","T190472-","C190473-","A190474-","C190475-","A190476-","A190477-","A190478-","C190479-","T190480-","A190481-","G190482-","T190483-","A190484-","C190485-","A190486-","T190487-","T190488-","A190489-","C190490-","T190491-","T190492-","C190493-","A190494-","A190495-","T190496-","C190497-","T190498-","G190499-","A190500-","A190501-","A190502-","A190503-","T190504-","A190505-","A190506-","A190507-","T190508-","G190509-","G190510-","A190511-","A190512-","G190513-","T190514-","G190515-","A190516-","T190517-","A190518-","T190519-","A190520-","A190521-","C190522-","T190523-","A190524-","A190525-","T190526-","A190527-","C190528-","A190529-","G190530-","C190531-","A190532-","G190533-","A190534-","T190535-","A190536-","T190537-","A190538-","T190539-","T190540-","G190541-","C190542-","T190543-","G190544-","G190545-","A190546-","C190547-","A190548-","A190549-","T190550-","T190551-","A190552-","T190553-","C190554-","C190555-","A190556-","A190557-","T190558-","T190559-","A190560-","T190561-","G190562-","A190563-","C190564-","C190565-","T190566-","T190567-","T190568-","G190569-","A190570-","T190571-","G190572-","G190573-","A190574-","A190575-","A190576-","G190577-","G190578-","A190579-","T190580-","A190581-","T190582-","T190583-","T190584-","A190585-","T190586-","C190587-","C190588-","A190589-","T190590-","C190591-","T190592-","A190593-","T190594-","C190595-","T190596-","C190597-","G190598-","T190599-","T190600-","C190601-","A190602-","T190603-","G190604-","G190605-","T190606-","C190607-","G190608-","G190609-","T190610-","A190611-","A190612-","T190613-","A190614-","A190615-","A190616-","C190617-","T190618-","T190619-","T190620-","T190621-","C190622-","C190623-","T190624-","A190625-","G190626-","A190627-","T190628-","C190629-","T190630-","T190631-","T190632-","A190633-","T190634-","A190635-","A190636-","A190637-","A190638-","A190639-","T190640-","A190641-","T190642-","C190643-","T190644-","T190645-","T190646-","G190647-","A190648-","A190649-","G190650-","A190651-","A190652-","T190653-","T190654-","T190655-","T190656-","T190657-","C190658-","A190659-","G190660-","A190661-","C190662-","T190663-","A190664-","T190665-","T190666-","T190667-","C190668-","G190669-","A190670-","G190671-","T190672-","A190673-","T190674-","C190675-","T190676-","G190677-","T190678-","A190679-","A190680-","G190681-","T190682-","A190683-","G190684-","T190685-","C190686-","A190687-","A190688-","T190689-","A190690-","C190691-","G190692-","A190693-","G190694-","G190695-","A190696-","A190697-","T190698-","T190699-","A190700-","G190701-","A190702-","A190703-","T190704-","A190705-","T190706-","T190707-","A190708-","T190709-","T190710-","A190711-","T190712-","T190713-","C190714-","A190715-","T190716-","G190717-","T190718-","G190719-","A190720-","T190721-","T190722-","A190723-","T190724-","A190725-","C190726-","T190727-","A190728-","A190729-","C190730-","A190731-","A190732-","C190733-","C190734-","G190735-","T190736-","C190737-","C190738-","T190739-","A190740-","C190741-","A190742-","A190743-","T190744-","T190745-","A190746-","A190747-","A190748-","C190749-","A190750-","A190751-","C190752-","A190753-","T190754-","T190755-","A190756-","C190757-","T190758-","T190759-","T190760-","T190761-","A190762-","T190763-","A190764-","A190765-","C190766-","G190767-","G190768-","C190769-","G190770-","A190771-","C190772-","G190773-","A190774-","A190775-","T190776-","A190777-","T190778-","A190779-","C190780-","T190781-","G190782-","A190783-","A190784-","A190785-","T190786-","T190787-","G190788-","A190789-","T190790-","A190791-","G190792-","A190793-","T190794-","C190795-","G190796-","A190797-","A190798-","A190799-","A190800-","A190801-","A190802-","G190803-","C190804-","C190805-","A190806-","C190807-","T190808-","A190809-","A190810-","T190811-","A190812-","A190813-","A190814-","A190815-","A190816-","C190817-","A190818-","G190819-","T190820-","T190821-","G190822-","G190823-","T190824-","T190825-","A190826-","A190827-","T190828-","T190829-","A190830-","C190831-","T190832-","T190833-","C190834-","A190835-","G190836-","G190837-","C190838-","T190839-","T190840-","T190841-","A190842-","G190843-","A190844-","C190845-","T190846-","A190847-","C190848-","A190849-","A190850-","A190851-","A190852-","A190853-","T190854-","G190855-","G190856-","T190857-","T190858-","C190859-","G190860-","A190861-","T190862-","A190863-","G190864-","C190865-","G190866-","A190867-","A190868-","G190869-","A190870-","T190871-","T190872-","G190873-","T190874-","A190875-","T190876-","A190877-","A190878-","T190879-","T190880-","T190881-","A190882-","T190883-","C190884-","T190885-","C190886-","A190887-","G190888-","A190889-","T190890-","C190891-","T190892-","T190893-","T190894-","A190895-","G190896-","T190897-","T190898-","A190899-","G190900-","A190901-","A190902-","G190903-","A190904-","A190905-","T190906-","G190907-","G190908-","A190909-","A190910-","G190911-","A190912-","C190913-","A190914-","G190915-","T190916-","A190917-","A190918-","C190919-","A190920-","A190921-","A190922-","A190923-","A190924-","C190925-","A190926-","G190927-","T190928-","A190929-","A190930-","A190931-","A190932-","A190933-","A190934-","A190935-","C190936-","T190937-","T190938-","A190939-","G190940-","T190941-","A190942-","C190943-","T190944-","T190945-","A190946-","G190947-","A190948-","T190949-","A190950-","T190951-","C190952-","G190953-","A190954-","A190955-","A190956-","A190957-","A190958-","A190959-","T190960-","A190961-","T190962-","A190963-","T190964-","T190965-","T190966-","T190967-","T190968-","G190969-","T190970-","A190971-","G190972-","A190973-","C190974-","T190975-","C190976-","T190977-","T190978-","G190979-","A190980-","G190981-","A190982-","A190983-","T190984-","A190985-","G190986-","A190987-","A190988-","G190989-","G190990-","A190991-","A190992-","A190993-","A190994-","C190995-","A190996-","T190997-","G190998-","T190999-","A191000-","C191001-","A191002-","T191003-","A191004-","A191005-","T191006-","T191007-","A191008-","T191009-","A191010-","A191011-","A191012-","A191013-","A191014-","A191015-","T191016-","G191017-","A191018-","A191019-","A191020-","A191021-","T191022-","C191023-","A191024-","A191025-","T191026-","G191027-","G191028-","C191029-","G191030-","A191031-","A191032-","T191033-","A191034-","A191035-","G191036-","A191037-","C191038-","A191039-","G191040-","T191041-","G191042-","C191043-","G191044-","A191045-","T191046-","T191047-","C191048-","G191049-","C191050-","A191051-","C191052-","C191053-","A191054-","T191055-","G191056-","G191057-","A191058-","G191059-","T191060-","C191061-","G191062-","G191063-","T191064-","A191065-","G191066-","A191067-","T191068-","T191069-","T191070-","C191071-","A191072-","T191073-","G191074-","G191075-","C191076-","T191077-","G191078-","T191079-","C191080-","G191081-","A191082-","T191083-","G191084-","A191085-","G191086-","C191087-","A191088-","G191089-","T191090-","T191091-","T191092-","C191093-","A191094-","C191095-","G191096-","A191097-","C191098-","G191099-","A191100-","C191101-","C191102-","T191103-","C191104-","G191105-","A191106-","T191107-","C191108-","T191109-","T191110-","T191111-","G191112-","G191113-","T191114-","C191115-","A191116-","T191117-","T191118-","A191119-","T191120-","C191121-","T191122-","T191123-","T191124-","G191125-","G191126-","T191127-","A191128-","G191129-","A191130-","T191131-","G191132-","A191133-","T191134-","T191135-","A191136-","T191137-","A191138-","A191139-","A191140-","A191141-","A191142-","A191143-","C191144-","A191145-","T191146-","G191147-","G191148-","A191149-","T191150-","T191151-","A191152-","G191153-","G191154-","T191155-","G191156-","T191157-","T191158-","G191159-","A191160-","C191161-","T191162-","G191163-","T191164-","T191165-","A191166-","T191167-","G191168-","T191169-","T191170-","C191171-","T191172-","A191173-","G191174-","A191175-","A191176-","C191177-","C191178-","A191179-","G191180-","T191181-","T191182-","G191183-","T191184-","T191185-","G191186-","A191187-","C191188-","A191189-","G191190-","G191191-","A191192-","A191193-","A191194-","A191195-","T191196-","A191197-","T191198-","T191199-","T191200-","G191201-","A191202-","T191203-","A191204-","G191205-","A191206-","T191207-","T191208-","T191209-","C191210-","T191211-","C191212-","C191213-","T191214-","T191215-","G191216-","A191217-","A191218-","C191219-","C191220-","A191221-","A191222-","T191223-","T191224-","T191225-","G191226-","T191227-","G191228-","A191229-","T191230-","C191231-","C191232-","T191233-","G191234-","T191235-","A191236-","G191237-","A191238-","T191239-","G191240-","T191241-","T191242-","C191243-","T191244-","G191245-","T191246-","A191247-","T191248-","G191249-","A191250-","T191251-","T191252-","A191253-","T191254-","T191255-","T191256-","T191257-","A191258-","G191259-","G191260-","A191261-","T191262-","T191263-","C191264-","A191265-","T191266-","A191267-","G191268-","A191269-","G191270-","A191271-","T191272-","A191273-","A191274-","T191275-","A191276-","T191277-","T191278-","G191279-","A191280-","T191281-","C191282-","A191283-","G191284-","T191285-","A191286-","T191287-","A191288-","T191289-","A191290-","G191291-","T191292-","A191293-","G191294-","A191295-","T191296-","A191297-","G191298-","A191299-","C191300-","T191301-","G191302-","T191303-","T191304-","T191305-","G191306-","C191307-","A191308-","T191309-","A191310-","T191311-","A191312-","T191313-","T191314-","A191315-","C191316-","A191317-","T191318-","A191319-","T191320-","A191321-","A191322-","A191323-","G191324-","A191325-","T191326-","A191327-","T191328-","T191329-","A191330-","T191331-","A191332-","T191333-","C191334-","T191335-","G191336-","C191337-","A191338-","T191339-","T191340-","A191341-","G191342-","T191343-","G191344-","T191345-","C191346-","A191347-","A191348-","A191349-","G191350-","A191351-","A191352-","T191353-","T191354-","A191355-","T191356-","A191357-","T191358-","G191359-","G191360-","A191361-","A191362-","G191363-","A191364-","T191365-","A191366-","T191367-","T191368-","T191369-","T191370-","C191371-","T191372-","C191373-","T191374-","A191375-","T191376-","A191377-","A191378-","T191379-","T191380-","A191381-","T191382-","T191383-","A191384-","A191385-","G191386-","A191387-","A191388-","T191389-","T191390-","G191391-","T191392-","A191393-","A191394-","T191395-","T191396-","C191397-","T191398-","G191399-","T191400-","G191401-","C191402-","A191403-","A191404-","G191405-","A191406-","T191407-","C191408-","T191409-","C191410-","T191411-","T191412-","A191413-","C191414-","T191415-","T191416-","T191417-","A191418-","C191419-","T191420-","A191421-","T191422-","C191423-","T191424-","A191425-","T191426-","C191427-","T191428-","A191429-","A191430-","T191431-","G191432-","C191433-","A191434-","T191435-","A191436-","T191437-","G191438-","T191439-","A191440-","G191441-","A191442-","A191443-","A191444-","T191445-","A191446-","G191447-","A191448-","C191449-","A191450-","T191451-","T191452-","G191453-","T191454-","T191455-","G191456-","A191457-","T191458-","C191459-","T191460-","T191461-","A191462-","T191463-","G191464-","G191465-","T191466-","A191467-","G191468-","A191469-","T191470-","C191471-","A191472-","T191473-","G191474-","G191475-","G191476-","G191477-","C191478-","T191479-","G191480-","T191481-","A191482-","A191483-","T191484-","A191485-","T191486-","A191487-","T191488-","A191489-","A191490-","A191491-","A191492-","T191493-","A191494-","G191495-","A191496-","A191497-","T191498-","G191499-","C191500-","T191501-","T191502-","G191503-","A191504-","A191505-","T191506-","G191507-","C191508-","C191509-","T191510-","A191511-","T191512-","T191513-","T191514-","T191515-","A191516-","G191517-","G191518-","G191519-","G191520-","A191521-","A191522-","T191523-","A191524-","T191525-","G191526-","T191527-","A191528-","A191529-","A191530-","A191531-","A191532-","G191533-","G191534-","A191535-","A191536-","A191537-","G191538-","T191539-","A191540-","G191541-","T191542-","G191543-","T191544-","T191545-","G191546-","T191547-","T191548-","G191549-","A191550-","G191551-","T191552-","T191553-","T191554-","A191555-","T191556-","T191557-","T191558-","T191559-","G191560-","A191561-","A191562-","T191563-","T191564-","G191565-","T191566-","G191567-","G191568-","T191569-","A191570-","T191571-","C191572-","C191573-","C191574-","A191575-","G191576-","A191577-","T191578-","G191579-","A191580-","A191581-","A191582-","A191583-","T191584-","G191585-","A191586-","T191587-","G191588-","T191589-","T191590-","A191591-","A191592-","A191593-","T191594-","T191595-","A191596-","G191597-","A191598-","T191599-","C191600-","T191601-","A191602-","T191603-","A191604-","T191605-","A191606-","A191607-","A191608-","A191609-","T191610-","A191611-","A191612-","T191613-","T191614-","C191615-","A191616-","G191617-","T191618-","A191619-","T191620-","A191621-","C191622-","T191623-","A191624-","G191625-","G191626-","G191627-","G191628-","A191629-","T191630-","T191631-","C191632-","C191633-","T191634-","T191635-","G191636-","T191637-","A191638-","G191639-","A191640-","T191641-","G191642-","A191643-","A191644-","C191645-","C191646-","C191647-","A191648-","C191649-","A191650-","G191651-","T191652-","A191653-","T191654-","T191655-","A191656-","G191657-","A191658-","A191659-","A191660-","T191661-","T191662-","T191663-","A191664-","T191665-","A191666-","A191667-","G191668-","C191669-","T191670-","T191671-","T191672-","G191673-","T191674-","A191675-","T191676-","C191677-","C191678-","C191679-","A191680-","T191681-","A191682-","T191683-","A191684-","T191685-","T191686-","G191687-","A191688-","A191689-","G191690-","A191691-","T191692-","A191693-","T191694-","C191695-","A191696-","A191697-","T191698-","C191699-","A191700-","A191701-","C191702-","T191703-","A191704-","G191705-","A191706-","T191707-","G191708-","C191709-","T191710-","G191711-","G191712-","T191713-","G191714-","G191715-","A191716-","A191717-","G191718-","G191719-","A191720-","C191721-","C191722-","T191723-","T191724-","G191725-","C191726-","T191727-","T191728-","T191729-","A191730-","T191731-","C191732-","G191733-","C191734-","G191735-","C191736-","T191737-","A191738-","T191739-","C191740-","T191741-","A191742-","T191743-","G191744-","C191745-","A191746-","G191747-","G191748-","T191749-","T191750-","A191751-","T191752-","A191753-","T191754-","A191755-","G191756-","A191757-","T191758-","T191759-","T191760-","A191761-","G191762-","T191763-","A191764-","T191765-","C191766-","A191767-","T191768-","G191769-","G191770-","C191771-","T191772-","A191773-","T191774-","T191775-","A191776-","G191777-","A191778-","A191779-","A191780-","A191781-","T191782-","G191783-","G191784-","A191785-","G191786-","C191787-","A191788-","A191789-","A191790-","T191791-","G191792-","T191793-","C191794-","A191795-","A191796-","C191797-","G191798-","C191799-","A191800-","G191801-","T191802-","A191803-","A191804-","T191805-","G191806-","A191807-","G191808-","T191809-","A191810-","A191811-","T191812-","G191813-","G191814-","A191815-","T191816-","A191817-","T191818-","A191819-","C191820-","A191821-","T191822-","G191823-","T191824-","C191825-","T191826-","T191827-","G191828-","A191829-","C191830-","G191831-","T191832-","G191833-","G191834-","C191835-","C191836-","G191837-","T191838-","G191839-","G191840-","A191841-","T191842-","A191843-","G191844-","G191845-","G191846-","G191847-","A191848-","T191849-","C191850-","T191851-","G191852-","T191853-","C191854-","A191855-","T191856-","C191857-","G191858-","C191859-","C191860-","C191861-","G191862-","T191863-","A191864-","G191865-","G191866-","G191867-","A191868-","A191869-","G191870-","C191871-","A191872-","C191873-","A191874-","T191875-","C191876-","T191877-","T191878-","A191879-","A191880-","A191881-","A191882-","T191883-","A191884-","T191885-","T191886-","A191887-","G191888-","A191889-","A191890-","A191891-","T191892-","A191893-","T191894-","T191895-","G191896-","C191897-","T191898-","T191899-","A191900-","G191901-","A191902-","G191903-","A191904-","A191905-","C191906-","C191907-","A191908-","T191909-","T191910-","G191911-","T191912-","C191913-","T191914-","A191915-","T191916-","T191917-","G191918-","A191919-","C191920-","T191921-","G191922-","T191923-","A191924-","T191925-","A191926-","A191927-","A191928-","A191929-","T191930-","T191931-","A191932-","G191933-","C191934-","T191935-","A191936-","T191937-","A191938-","C191939-","T191940-","T191941-","A191942-","A191943-","T191944-","A191945-","A191946-","T191947-","A191948-","C191949-","A191950-","A191951-","T191952-","T191953-","G191954-","A191955-","A191956-","A191957-","A191958-","C191959-","C191960-","A191961-","T191962-","G191963-","A191964-","T191965-","G191966-","T191967-","G191968-","A191969-","T191970-","A191971-","A191972-","A191973-","G191974-","C191975-","T191976-","C191977-","T191978-","G191979-","T191980-","A191981-","T191982-","C191983-","A191984-","A191985-","G191986-","T191987-","A191988-","T191989-","T191990-","T191991-","T191992-","A191993-","T191994-","G191995-","A191996-","T191997-","G191998-","G191999-","T192000-","A192001-","G192002-","A192003-","T192004-","T192005-","A192006-","T192007-","T192008-","C192009-","A192010-","C192011-","T192012-","T192013-","T192014-","G192015-","T192016-","A192017-","A192018-","T192019-","G192020-","T192021-","G192022-","T192023-","A192024-","T192025-","G192026-","C192027-","A192028-","T192029-","C192030-","A192031-","T192032-","C192033-","A192034-","C192035-","T192036-","C192037-","T192038-","T192039-","T192040-","G192041-","A192042-","T192043-","T192044-","A192045-","T192046-","A192047-","T192048-","A192049-","A192050-","T192051-","T192052-","G192053-","A192054-","T192055-","T192056-","G192057-","T192058-","A192059-","A192060-","A192061-","C192062-","A192063-","A192064-","G192065-","A192066-","A192067-","T192068-","T192069-","G192070-","G192071-","A192072-","G192073-","T192074-","A192075-","C192076-","A192077-","T192078-","T192079-","A192080-","G192081-","G192082-","C192083-","A192084-","G192085-","A192086-","T192087-","G192088-","A192089-","A192090-","A192091-","A192092-","T192093-","T192094-","C192095-","A192096-","T192097-","A192098-","A192099-","T192100-","A192101-","C192102-","A192103-","A192104-","C192105-","C192106-","A192107-","T192108-","G192109-","T192110-","A192111-","T192112-","G192113-","A192114-","G192115-","T192116-","T192117-","A192118-","A192119-","T192120-","C192121-","T192122-","A192123-","T192124-","A192125-","A192126-","T192127-","A192128-","G192129-","A192130-","G192131-","A192132-","C192133-","A192134-","A192135-","A192136-","A192137-","A192138-","C192139-","A192140-","A192141-","G192142-","C192143-","A192144-","T192145-","G192146-","C192147-","T192148-","T192149-","C192150-","C192151-","C192152-","A192153-","T192154-","A192155-","T192156-","T192157-","C192158-","T192159-","A192160-","C192161-","A192162-","T192163-","A192164-","G192165-","G192166-","T192167-","A192168-","T192169-","T192170-","C192171-","T192172-","A192173-","A192174-","A192175-","C192176-","A192177-","T192178-","C192179-","C192180-","A192181-","G192182-","T192183-","T192184-","T192185-","T192186-","G192187-","A192188-","C192189-","A192190-","C192191-","A192192-","G192193-","T192194-","G192195-","T192196-","A192197-","T192198-","C192199-","A192200-","C192201-","T192202-","A192203-","A192204-","A192205-","G192206-","G192207-","A192208-","T192209-","T192210-","C192211-","A192212-","A192213-","G192214-","A192215-","T192216-","T192217-","T192218-","A192219-","C192220-","A192221-","C192222-","A192223-","G192224-","A192225-","A192226-","G192227-","T192228-","A192229-","A192230-","C192231-","C192232-","G192233-","A192234-","G192235-","C192236-","A192237-","G192238-","G192239-","T192240-","C192241-","A192242-","C192243-","T192244-","A192245-","A192246-","A192247-","G192248-","C192249-","T192250-","C192251-","T192252-","A192253-","A192254-","A192255-","C192256-","A192257-","G192258-","A192259-","C192260-","G192261-","T192262-","G192263-","C192264-","T192265-","C192266-","T192267-","A192268-","A192269-","T192270-","A192271-","G192272-","A192273-","T192274-","G192275-","A192276-","G192277-","A192278-","T192279-","A192280-","A192281-","T192282-","A192283-","A192284-","A192285-","C192286-","A192287-","A192288-","T192289-","G192290-","T192291-","A192292-","T192293-","C192294-","A192295-","A192296-","C192297-","T192298-","G192299-","A192300-","T192301-","G192302-","A192303-","C192304-","A192305-","A192306-","T192307-","C192308-","T192309-","C192310-","C192311-","T192312-","A192313-","T192314-","C192315-","A192316-","A192317-","A192318-","A192319-","C192320-","T192321-","T192322-","C192323-","C192324-","A192325-","T192326-","T192327-","A192328-","G192329-","A192330-","A192331-","A192332-","T192333-","T192334-","A192335-","G192336-","G192337-","G192338-","A192339-","T192340-","C192341-","T192342-","A192343-","A192344-","T192345-","T192346-","G192347-","T192348-","T192349-","T192350-","C192351-","A192352-","C192353-","A192354-","A192355-","G192356-","C192357-","T192358-","G192359-","T192360-","C192361-","A192362-","T192363-","A192364-","T192365-","A192366-","G192367-","A192368-","G192369-","T192370-","T192371-","C192372-","T192373-","A192374-","T192375-","C192376-","C192377-","A192378-","C192379-","C192380-","C192381-","A192382-","C192383-","C192384-","T192385-","T192386-","T192387-","C192388-","T192389-","T192390-","G192391-","A192392-","A192393-","A192394-","T192395-","G192396-","A192397-","G192398-","T192399-","T192400-","A192401-","A192402-","T192403-","A192404-","G192405-","T192406-","C192407-","A192408-","T192409-","A192410-","A192411-","G192412-","T192413-","T192414-","A192415-","G192416-","T192417-","T192418-","A192419-","A192420-","G192421-","T192422-","C192423-","A192424-","T192425-","A192426-","A192427-","G192428-","T192429-","T192430-","A192431-","G192432-","T192433-","T192434-","A192435-","A192436-","G192437-","T192438-","C192439-","A192440-","T192441-","A192442-","A192443-","G192444-","T192445-","T192446-","A192447-","G192448-","T192449-","T192450-","A192451-","A192452-","G192453-","T192454-","C192455-","A192456-","T192457-","A192458-","A192459-","G192460-","T192461-","T192462-","A192463-","G192464-","T192465-","T192466-","A192467-","A192468-","G192469-","T192470-","C192471-","A192472-","T192473-","A192474-","A192475-","G192476-","T192477-","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-","A192490-","A192491-","G192492-","T192493-","T192494-","A192495-","G192496-","T192497-","T192498-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-","T192531-","A192532-","T192533-","A192534-","G192535-","T192536-","C192537-","T192538-","A192539-","A192540-","C192541-","A192542-","C192543-","T192544-","T192545-","C192546-","T192547-","A192548-","A192549-","T192550-","T192551-","T192552-","T192553-","T192554-","A192555-","T192556-","A192557-","C192558-","C192559-","T192560-","T192561-","G192562-","A192563-","T192564-","C192565-","T192566-","T192567-","T192568-","T192569-","T192570-","C192571-","T192572-","C192573-","T192574-","A192575-","A192576-","T192577-","T192578-","A192579-","T192580-","G192581-","A192582-","A192583-","A192584-","A192585-","A192586-","G192587-","T192588-","A192589-","A192590-","A192591-","T192592-","C192593-","A192594-","T192595-","T192596-","A192597-","T192598-","G192599-","A192600-","A192601-","G192602-","A192603-","T192604-","G192605-","G192606-","A192607-","T192608-","G192609-","A192610-","A192611-","A192612-","T192613-","G192614-","G192615-","A192616-","C192617-","G192618-","A192619-","G192620-","A192621-","T192622-","T192623-","G192624-","T192625-","G192626-","C192627-","G192628-","C192629-","A192630-","T192631-","C192632-","G192633-","T192634-","T192635-","A192636-","A192637-","C192638-","G192639-","A192640-","T192641-","A192642-","G192643-","T192644-","A192645-","T192646-","G192647-","T192648-","G192649-","G192650-","T192651-","A192652-","C192653-","G192654-","T192655-","A192656-","C192657-","C192658-","T192659-","A192660-","A192661-","C192662-","G192663-","C192664-","A192665-","T192666-","T192667-","T192668-","A192669-","T192670-","G192671-","G192672-","A192673-","C192674-","G192675-","A192676-","C192677-","G192678-","G192679-","T192680-","G192681-","A192682-","T192683-","A192684-","A192685-","T192686-","G192687-","A192688-","A192689-","G192690-","G192691-","T192692-","C192693-","A192694-","C192695-","A192696-","T192697-","T192698-","T192699-","C192700-","T192701-","G192702-","T192703-","C192704-","A192705-","A192706-","T192707-","A192708-","A192709-","T192710-","G192711-","T192712-","C192713-","T192714-","G192715-","T192716-","C192717-","A192718-","T192719-","A192720-","T192721-","G192722-","T192723-","A192724-","T192725-","C192726-","T192727-","C192728-","G192729-","C192730-","A192731-","T192732-","T192733-","C192734-","T192735-","T192736-","T192737-","G192738-","A192739-","T192740-","G192741-","T192742-","G192743-","G192744-","A192745-","T192746-","A192747-","T192748-","A192749-","T192750-","C192751-","A192752-","T192753-","C192754-","T192755-","C192756-","A192757-","T192758-","C192759-","T192760-","G192761-","T192762-","T192763-","T192764-","A192765-","A192766-","A192767-","T192768-","T192769-","A192770-","G192771-","T192772-","T192773-","A192774-","T192775-","T192776-","A192777-","A192778-","A192779-","C192780-","A192781-","C192782-","T192783-","G192784-","C192785-","G192786-","A192787-","T192788-","C192789-","T192790-","G192791-","A192792-","A192793-","T192794-","A192795-","A192796-","A192797-","C192798-","G192799-","A192800-","C192801-","T192802-","A192803-","A192804-","A192805-","A192806-","T192807-","G192808-","T192809-","G192810-","G192811-","T192812-","A192813-","A192814-","C192815-","T192816-","C192817-","T192818-","C192819-","C192820-","A192821-","T192822-","T192823-","A192824-","C192825-","A192826-","T192827-","T192828-","G192829-","C192830-","T192831-","A192832-","T192833-","A192834-","C192835-","G192836-","A192837-","T192838-","G192839-","A192840-","A192841-","T192842-","A192843-","C192844-","A192845-","C192846-","G192847-","A192848-","T192849-","T192850-","T192851-","A192852-","A192853-","T192854-","C192855-","C192856-","A192857-","T192858-","C192859-","T192860-","G192861-","T192862-","A192863-","T192864-","T192865-","A192866-","A192867-","A192868-","G192869-","A192870-","T192871-","A192872-","T192873-","T192874-","G192875-","T192876-","T192877-","A192878-","C192879-","G192880-","C192881-","C192882-","A192883-","C192884-","G192885-","G192886-","C192887-","A192888-","T192889-","G192890-","C192891-","G192892-","T192893-","A192894-","A192895-","C192896-","T192897-","T192898-","T192899-","G192900-","A192901-","T192902-","A192903-","G192904-","C192905-","A192906-","A192907-","G192908-","G192909-","A192910-","T192911-","A192912-","A192913-","A192914-","A192915-","A192916-","A192917-","G192918-","G192919-","A192920-","C192921-","A192922-","T192923-","A192924-","T192925-","T192926-","C192927-","C192928-","T192929-","C192930-","T192931-","A192932-","C192933-","A192934-","C192935-","C192936-","A192937-","C192938-","T192939-","A192940-","T192941-","C192942-","T192943-","G192944-","A192945-","T192946-","T192947-","C192948-","A192949-","T192950-","T192951-","C192952-","A192953-","C192954-","T192955-","A192956-","T192957-","C192958-","A192959-","A192960-","T192961-","C192962-","G192963-","A192964-","T192965-","A192966-","A192967-","C192968-","A192969-","A192970-","G192971-","A192972-","T192973-","C192974-","T192975-","T192976-","T192977-","G192978-","A192979-","T192980-","A192981-","T192982-","A192983-","C192984-","T192985-","A192986-","A192987-","C192988-","G192989-","G192990-","A192991-","C192992-","C192993-","C192994-","C192995-","A192996-","T192997-","T192998-","G192999-","A193000-","T193001-","G193002-","A193003-","C193004-","T193005-","T193006-","T193007-","A193008-","G193009-","T193010-","A193011-","A193012-","A193013-","T193014-","C193015-","A193016-","T193017-","C193018-","C193019-","G193020-","A193021-","T193022-","C193023-","T193024-","A193025-","T193026-","T193027-","G193028-","C193029-","T193030-","G193031-","T193032-","G193033-","T193034-","T193035-","A193036-","T193037-","C193038-","T193039-","T193040-","A193041-","G193042-","A193043-","T193044-","A193045-","T193046-","A193047-","A193048-","A193049-","T193050-","T193051-","C193052-","A193053-","A193054-","T193055-","G193056-","G193057-","G193058-","A193059-","G193060-","C193061-","T193062-","T193063-","A193064-","A193065-","A193066-","C193067-","T193068-","A193069-","T193070-","T193071-","A193072-","C193073-","G193074-","T193075-","T193076-","C193077-","T193078-","G193079-","T193080-","A193081-","C193082-","A193083-","A193084-","A193085-","T193086-","T193087-","A193088-","T193089-","T193090-","G193091-","A193092-","C193093-","T193094-","A193095-","A193096-","A193097-","G193098-","G193099-","A193100-","T193101-","C193102-","T193103-","G193104-","A193105-","C193106-","C193107-","C193108-","T193109-","A193110-","A193111-","T193112-","T193113-","G193114-","C193115-","G193116-","T193117-","C193118-","G193119-","A193120-","T193121-","G193122-","A193123-","G193124-","G193125-","A193126-","T193127-","G193128-","G193129-","A193130-","C193131-","T193132-","C193133-","A193134-","C193135-","T193136-","T193137-","C193138-","T193139-","C193140-","T193141-","T193142-","C193143-","A193144-","T193145-","T193146-","A193147-","C193148-","T193149-","A193150-","C193151-","T193152-","G193153-","T193154-","A193155-","A193156-","A193157-","C193158-","A193159-","C193160-","A193161-","T193162-","A193163-","T193164-","C193165-","C193166-","G193167-","C193168-","G193169-","T193170-","T193171-","C193172-","C193173-","A193174-","C193175-","G193176-","A193177-","A193178-","A193179-","G193180-","C193181-","A193182-","A193183-","T193184-","T193185-","A193186-","T193187-","T193188-","A193189-","C193190-","A193191-","A193192-","G193193-","T193194-","C193195-","A193196-","A193197-","A193198-","G193199-","A193200-","G193201-","T193202-","C193203-","A193204-","C193205-","A193206-","C193207-","T193208-","A193209-","A193210-","G193211-","A193212-","T193213-","G193214-","C193215-","G193216-","A193217-","G193218-","C193219-","T193220-","G193221-","A193222-","G193223-","A193224-","A193225-","G193226-","C193227-","G193228-","A193229-","T193230-","T193231-","C193232-","A193233-","T193234-","C193235-","T193236-","A193237-","C193238-","G193239-","C193240-","G193241-","A193242-","T193243-","A193244-","A193245-","T193246-","A193247-","G193248-","A193249-","T193250-","C193251-","A193252-","T193253-","G193254-","G193255-","A193256-","G193257-","C193258-","A193259-","A193260-","A193261-","C193262-","A193263-","T193264-","T193265-","A193266-","A193267-","C193268-","G193269-","C193270-","G193271-","G193272-","T193273-","T193274-","A193275-","C193276-","G193277-","A193278-","A193279-","A193280-","A193281-","T193282-","C193283-","G193284-","G193285-","A193286-","A193287-","A193288-","T193289-","A193290-","C193291-","G193292-","C193293-","C193294-","G193295-","T193296-","T193297-","A193298-","C193299-","A193300-","C193301-","A193302-","C193303-","T193304-","T193305-","A193306-","C193307-","C193308-","T193309-","T193310-","C193311-","A193312-","A193313-","C193314-","A193315-","G193316-","T193317-","A193318-","T193319-","A193320-","C193321-","C193322-","A193323-","A193324-","A193325-","C193326-","A193327-","T193328-","A193329-","G193330-","T193331-","C193332-","C193333-","T193334-","C193335-","G193336-","T193337-","G193338-","T193339-","G193340-","G193341-","T193342-","G193343-","T193344-","A193345-","T193346-","G193347-","C193348-","T193349-","C193350-","T193351-","T193352-","T193353-","T193354-","A193355-","T193356-","C193357-","T193358-","C193359-","G193360-","A193361-","G193362-","G193363-","A193364-","G193365-","C193366-","C193367-","G193368-","A193369-","T193370-","A193371-","C193372-","G193373-","A193374-","G193375-","G193376-","A193377-","T193378-","A193379-","C193380-","G193381-","T193382-","A193383-","A193384-","T193385-","A193386-","A193387-","T193388-","C193389-","T193390-","T193391-","A193392-","A193393-","T193394-","T193395-","G193396-","T193397-","A193398-","C193399-","A193400-","C193401-","C193402-","C193403-","A193404-","T193405-","C193406-","A193407-","T193408-","G193409-","G193410-","A193411-","A193412-","T193413-","A193414-","C193415-","A193416-","T193417-","A193418-","A193419-","A193420-","G193421-","A193422-","A193423-","C193424-","G193425-","A193426-","T193427-","T193428-","G193429-","T193430-","G193431-","C193432-","A193433-","A193434-","C193435-","A193436-","G193437-","G193438-","T193439-","C193440-","A193441-","T193442-","A193443-","T193444-","T193445-","C193446-","T193447-","C193448-","A193449-","T193450-","A193451-","A193452-","T193453-","G193454-","T193455-","T193456-","A193457-","C193458-","T193459-","C193460-","A193461-","A193462-","T193463-","T193464-","G193465-","G193466-","C193467-","A193468-","C193469-","G193470-","A193471-","A193472-","C193473-","A193474-","A193475-","A193476-","A193477-","A193478-","T193479-","A193480-","C193481-","G193482-","G193483-","G193484-","A193485-","A193486-","A193487-","T193488-","T193489-","A193490-","C193491-","A193492-","A193493-","A193494-","A193495-","G193496-","G193497-","A193498-","A193499-","G193500-","A193501-","A193502-","G193503-","G193504-","A193505-","C193506-","A193507-","A193508-","C193509-","A193510-","T193511-","C193512-","T193513-","A193514-","C193515-","T193516-","T193517-","T193518-","A193519-","T193520-","C193521-","T193522-","A193523-","T193524-","T193525-","C193526-","A193527-","T193528-","A193529-","A193530-","A193531-","A193532-","C193533-","A193534-","T193535-","A193536-","A193537-","T193538-","C193539-","A193540-","A193541-","G193542-","G193543-","A193544-","T193545-","A193546-","T193547-","G193548-","G193549-","A193550-","A193551-","G193552-","T193553-","C193554-","G193555-","C193556-","T193557-","C193558-","T193559-","C193560-","T193561-","C193562-","A193563-","A193564-","T193565-","A193566-","T193567-","A193568-","C193569-","T193570-","A193571-","C193572-","G193573-","G193574-","T193575-","A193576-","T193577-","C193578-","T193579-","A193580-","C193581-","T193582-","A193583-","G193584-","A193585-","T193586-","A193587-","G193588-","A193589-","T193590-","T193591-","C193592-","G193593-","A193594-","C193595-","A193596-","T193597-","T193598-","C193599-","A193600-","G193601-","A193602-","A193603-","A193604-","G193605-","A193606-","C193607-","G193608-","A193609-","A193610-","T193611-","A193612-","C193613-","T193614-","A193615-","T193616-","A193617-","A193618-","T193619-","A193620-","C193621-","A193622-","A193623-","T193624-","G193625-","A193626-","C193627-","T193628-","C193629-","C193630-","T193631-","C193632-","T193633-","T193634-","C193635-","A193636-","T193637-","A193638-","C193639-","C193640-","G193641-","C193642-","C193643-","T193644-","T193645-","C193646-","C193647-","A193648-","G193649-","A193650-","A193651-","T193652-","T193653-","G193654-","C193655-","A193656-","A193657-","T193658-","A193659-","A193660-","C193661-","A193662-","A193663-","T193664-","G193665-","T193666-","T193667-","G193668-","C193669-","C193670-","T193671-","C193672-","A193673-","T193674-","A193675-","C193676-","C193677-","T193678-","C193679-","G193680-","T193681-","A193682-","T193683-","A193684-","C193685-","A193686-","T193687-","T193688-","G193689-","G193690-","A193691-","T193692-","A193693-","C193694-","G193695-","A193696-","C193697-","A193698-","T193699-","C193700-","A193701-","A193702-","C193703-","C193704-","T193705-","T193706-","C193707-","C193708-","G193709-","A193710-","C193711-","T193712-","A193713-","A193714-","A193715-","G193716-","A193717-","C193718-","G193719-","A193720-","T193721-","A193722-","A193723-","G193724-","A193725-","C193726-","A193727-","G193728-","T193729-","A193730-","T193731-","T193732-","C193733-","G193734-","A193735-","C193736-","T193737-","T193738-","G193739-","G193740-","T193741-","G193742-","T193743-","T193744-","T193745-","G193746-","A193747-","A193748-","A193749-","A193750-","C193751-","A193752-","G193753-","A193754-","A193755-","A193756-","C193757-","A193758-","T193759-","T193760-","A193761-","T193762-","A193763-","T193764-","A193765-","C193766-","A193767-","A193768-","G193769-","G193770-","C193771-","G193772-","G193773-","A193774-","T193775-","G193776-","T193777-","C193778-","G193779-","T193780-","T193781-","A193782-","A193783-","T193784-","G193785-","A193786-","C193787-","A193788-","T193789-","T193790-","A193791-","T193792-","C193793-","C193794-","A193795-","C193796-","C193797-","A193798-","C193799-","A193800-","G193801-","A193802-","C193803-","T193804-","G193805-","A193806-","A193807-","A193808-","G193809-","T193810-","A193811-","T193812-","C193813-","T193814-","C193815-","T193816-","A193817-","C193818-","C193819-","T193820-","A193821-","T193822-","G193823-","A193824-","T193825-","T193826-","A193827-","A193828-","A193829-","T193830-","C193831-","G193832-","T193833-","T193834-","G193835-","T193836-","T193837-","C193838-","T193839-","A193840-","C193841-","A193842-","A193843-","G193844-","A193845-","T193846-","G193847-","T193848-","C193849-","G193850-","G193851-","A193852-","G193853-","T193854-","T193855-","C193856-","T193857-","C193858-","T193859-","C193860-","C193861-","C193862-","T193863-","A193864-","C193865-","G193866-","A193867-","C193868-","G193869-","A193870-","T193871-","C193872-","A193873-","C193874-","T193875-","A193876-","C193877-","G193878-","T193879-","A193880-","A193881-","A193882-","G193883-","A193884-","A193885-","G193886-","A193887-","T193888-","A193889-","A193890-","T193891-","A193892-","G193893-","C193894-","C193895-","T193896-","A193897-","C193898-","T193899-","G193900-","C193901-","C193902-","T193903-","A193904-","T193905-","T193906-","A193907-","A193908-","G193909-","G193910-","G193911-","A193912-","C193913-","G193914-","A193915-","G193916-","T193917-","C193918-","A193919-","T193920-","T193921-","T193922-","G193923-","C193924-","G193925-","G193926-","A193927-","A193928-","C193929-","T193930-","A193931-","C193932-","A193933-","T193934-","A193935-","C193936-","T193937-","A193938-","A193939-","A193940-","T193941-","T193942-","C193943-","T193944-","G193945-","T193946-","T193947-","T193948-","A193949-","A193950-","A193951-","C193952-","G193953-","A193954-","G193955-","G193956-","A193957-","C193958-","T193959-","A193960-","T193961-","A193962-","A193963-","A193964-","A193965-","G193966-","T193967-","G193968-","T193969-","A193970-","T193971-","T193972-","T193973-","A193974-","T193975-","G193976-","A193977-","A193978-","A193979-","A193980-","A193981-","T193982-","A193983-","T193984-","A193985-","T193986-","C193987-","A193988-","T193989-","T193990-","C193991-","G193992-","A193993-","T193994-","A193995-","A193996-","G193997-","A193998-","T193999-","A194000-","G194001-","A194002-","T194003-","T194004-","C194005-","C194006-","A194007-","T194008-","C194009-","A194010-","T194011-","C194012-","G194013-","A194014-","A194015-","A194016-","A194017-","A194018-","T194019-","G194020-","T194021-","A194022-","G194023-","T194024-","C194025-","G194026-","T194027-","G194028-","A194029-","C194030-","A194031-","T194032-","A194033-","A194034-","G194035-","T194036-","C194037-","T194038-","C194039-","C194040-","T194041-","C194042-","A194043-","A194044-","A194045-","G194046-","A194047-","G194048-","A194049-","T194050-","T194051-","C194052-","G194053-","A194054-","A194055-","T194056-","C194057-","T194058-","C194059-","A194060-","G194061-","A194062-","C194063-","A194064-","C194065-","C194066-","G194067-","A194068-","C194069-","T194070-","T194071-","G194072-","T194073-","A194074-","T194075-","A194076-","C194077-","G194078-","G194079-","T194080-","A194081-","T194082-","T194083-","G194084-","A194085-","G194086-","A194087-","A194088-","C194089-","A194090-","G194091-","A194092-","A194093-","G194094-","A194095-","C194096-","A194097-","T194098-","T194099-","C194100-","G194101-","G194102-","T194103-","A194104-","T194105-","C194106-","A194107-","C194108-","A194109-","C194110-","A194111-","T194112-","A194113-","T194114-","C194115-","T194116-","C194117-","G194118-","A194119-","A194120-","G194121-","C194122-","C194123-","A194124-","T194125-","A194126-","C194127-","A194128-","T194129-","T194130-","C194131-","A194132-","G194133-","A194134-","C194135-","A194136-","A194137-","A194138-","C194139-","G194140-","C194141-","A194142-","T194143-","T194144-","T194145-","C194146-","A194147-","T194148-","T194149-","T194150-","C194151-","C194152-","C194153-","A194154-","T194155-","G194156-","T194157-","A194158-","C194159-","G194160-","A194161-","C194162-","G194163-","A194164-","T194165-","C194166-","T194167-","C194168-","A194169-","T194170-","A194171-","G194172-","A194173-","A194174-","C194175-","A194176-","G194177-","T194178-","G194179-","T194180-","C194181-","A194182-","T194183-","C194184-","T194185-","A194186-","T194187-","C194188-","G194189-","A194190-","T194191-","G194192-","G194193-","A194194-","G194195-","C194196-","A194197-","T194198-","A194199-","A194200-","A194201-","A194202-","G194203-","T194204-","A194205-","A194206-","A194207-","C194208-","T194209-","C194210-","G194211-","T194212-","C194213-","G194214-","A194215-","C194216-","A194217-","A194218-","A194219-","G194220-","C194221-","A194222-","C194223-","T194224-","C194225-","A194226-","A194227-","T194228-","A194229-","A194230-","A194231-","T194232-","T194233-","A194234-","G194235-","A194236-","G194237-","T194238-","C194239-","T194240-","A194241-","C194242-","C194243-","A194244-","T194245-","C194246-","G194247-","A194248-","T194249-","A194250-","G194251-","T194252-","C194253-","A194254-","A194255-","T194256-","C194257-","T194258-","A194259-","G194260-","A194261-","C194262-","T194263-","A194264-","T194265-","C194266-","G194267-","T194268-","A194269-","T194270-","T194271-","T194272-","G194273-","C194274-","C194275-","T194276-","C194277-","C194278-","G194279-","G194280-","A194281-","A194282-","A194283-","T194284-","T194285-","A194286-","T194287-","G194288-","C194289-","G194290-","C194291-","A194292-","A194293-","T194294-","A194295-","T194296-","C194297-","A194298-","T194299-","A194300-","A194301-","C194302-","C194303-","A194304-","A194305-","G194306-","C194307-","T194308-","A194309-","A194310-","G194311-","C194312-","G194313-","A194314-","C194315-","T194316-","A194317-","C194318-","C194319-","A194320-","T194321-","C194322-","T194323-","A194324-","A194325-","A194326-","C194327-","A194328-","G194329-","T194330-","A194331-","T194332-","G194333-","T194334-","T194335-","G194336-","T194337-","A194338-","C194339-","G194340-","G194341-","A194342-","A194343-","A194344-","G194345-","A194346-","A194347-","C194348-","C194349-","A194350-","T194351-","T194352-","A194353-","C194354-","A194355-","A194356-","A194357-","T194358-","A194359-","T194360-","T194361-","A194362-","T194363-","C194364-","C194365-","A194366-","T194367-","G194368-","A194369-","T194370-","A194371-","G194372-","A194373-","A194374-","A194375-","G194376-","A194377-","A194378-","A194379-","A194380-","T194381-","A194382-","T194383-","T194384-","T194385-","A194386-","A194387-","A194388-","A194389-","A194390-","A194391-","T194392-","A194393-","A194394-","T194395-","C194396-","T194397-","A194398-","T194399-","A194400-","T194401-","G194402-","A194403-","T194404-","T194405-","G194406-","G194407-","A194408-","G194409-","A194410-","A194411-","G194412-","T194413-","A194414-","G194415-","G194416-","A194417-","A194418-","A194419-","C194420-","A194421-","A194422-","A194423-","C194424-","A194425-","G194426-","T194427-","A194428-","A194429-","C194430-","A194431-","A194432-","G194433-","A194434-","C194435-","G194436-","A194437-","C194438-","G194439-","A194440-","T194441-","T194442-","A194443-","C194444-","T194445-","A194446-","C194447-","A194448-","T194449-","T194450-","A194451-","T194452-","T194453-","A194454-","A194455-","A194456-","T194457-","C194458-","A194459-","T194460-","G194461-","A194462-","G194463-","G194464-","T194465-","C194466-","C194467-","G194468-","T194469-","A194470-","T194471-","T194472-","A194473-","T194474-","A194475-","C194476-","T194477-","C194478-","G194479-","T194480-","A194481-","T194482-","A194483-","T194484-","A194485-","T194486-","T194487-","G194488-","T194489-","T194490-","T194491-","C194492-","T194493-","C194494-","T194495-","C194496-","A194497-","T194498-","G194499-","T194500-","A194501-","T194502-","A194503-","A194504-","T194505-","A194506-","A194507-","T194508-","A194509-","A194510-","A194511-","C194512-","G194513-","G194514-","A194515-","A194516-","G194517-","A194518-","G194519-","A194520-","T194521-","A194522-","T194523-","A194524-","G194525-","C194526-","A194527-","C194528-","C194529-","A194530-","C194531-","A194532-","T194533-","G194534-","C194535-","A194536-","C194537-","C194538-","A194539-","T194540-","C194541-","C194542-","A194543-","A194544-","T194545-","G194546-","G194547-","A194548-","A194549-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","C194595-","G194596-","T194597-","G194598-","T194599-","C194600-","C194601-","T194602-","C194603-","C194604-","G194605-","G194606-","G194607-","A194608-","A194609-","C194610-","T194611-","T194612-","A194613-","C194614-","G194615-","C194616-","T194617-","T194618-","T194619-","C194620-","A194621-","G194622-","A194623-","T194624-","T194625-","A194626-","T194627-","G194628-","T194629-","G194630-","A194631-","T194632-","A194633-","G194634-","C194635-","A194636-","A194637-","G194638-","A194639-","C194640-","T194641-","A194642-","A194643-","T194644-","A194645-","C194646-","A194647-","C194648-","A194649-","A194650-","T194651-","G194652-","T194653-","A194654-","C194655-","A194656-","C194657-","C194658-","G194659-","T194660-","G194661-","T194662-","G194663-","G194664-","T194665-","T194666-","C194667-","G194668-","G194669-","A194670-","T194671-","A194672-","C194673-","C194674-","T194675-","T194676-","T194677-","A194678-","C194679-","A194680-","T194681-","C194682-","T194683-","C194684-","A194685-","C194686-","A194687-","A194688-","T194689-","A194690-","A194691-","T194692-","C194693-","A194694-","T194695-","T194696-","T194697-","A194698-","C194699-","A194700-","G194701-","G194702-","C194703-","T194704-","T194705-","G194706-","T194707-","C194708-","T194709-","A194710-","A194711-","G194712-","T194713-","T194714-","G194715-","T194716-","A194717-","A194718-","C194719-","G194720-","G194721-","A194722-","A194723-","G194724-","A194725-","T194726-","G194727-","T194728-","G194729-","A194730-","T194731-","A194732-","G194733-","T194734-","A194735-","A194736-","T194737-","C194738-","A194739-","G194740-","G194741-","T194742-","A194743-","G194744-","A194745-","G194746-","A194747-","C194748-","G194749-","C194750-","G194751-","A194752-","T194753-","C194754-","G194755-","T194756-","G194757-","T194758-","A194759-","A194760-","C194761-","A194762-","C194763-","G194764-","A194765-","C194766-","T194767-","C194768-","A194769-","C194770-","A194771-","A194772-","T194773-","A194774-","G194775-","A194776-","A194777-","T194778-","C194779-","T194780-","G194781-","T194782-","G194783-","A194784-","A194785-","T194786-","G194787-","C194788-","T194789-","C194790-","T194791-","C194792-","C194793-","A194794-","G194795-","G194796-","A194797-","T194798-","A194799-","T194800-","T194801-","A194802-","T194803-","T194804-","G194805-","T194806-","C194807-","T194808-","T194809-","C194810-","T194811-","C194812-","A194813-","A194814-","A194815-","G194816-","G194817-","A194818-","G194819-","C194820-","A194821-","T194822-","C194823-","A194824-","G194825-","G194826-","G194827-","T194828-","G194829-","T194830-","A194831-","G194832-","A194833-","A194834-","C194835-","A194836-","T194837-","G194838-","T194839-","A194840-","T194841-","T194842-","T194843-","C194844-","T194845-","A194846-","A194847-","A194848-","A194849-","C194850-","A194851-","A194852-","A194853-","G194854-","T194855-","G194856-","T194857-","G194858-","G194859-","A194860-","A194861-","T194862-","A194863-","G194864-","G194865-","A194866-","T194867-","A194868-","C194869-","G194870-","G194871-","A194872-","G194873-","T194874-","A194875-","T194876-","C194877-","C194878-","G194879-","G194880-","A194881-","T194882-","A194883-","C194884-","A194885-","C194886-","G194887-","T194888-","C194889-","T194890-","A194891-","C194892-","C194893-","G194894-","G194895-","A194896-","G194897-","A194898-","C194899-","G194900-","T194901-","C194902-","A194903-","T194904-","C194905-","T194906-","G194907-","T194908-","T194909-","C194910-","T194911-","C194912-","C194913-","G194914-","T194915-","G194916-","T194917-","G194918-","G194919-","T194920-","C194921-","C194922-","C194923-","G194924-","G194925-","A194926-","A194927-","C194928-","A194929-","T194930-","A194931-","T194932-","T194933-","C194934-","T194935-","C194936-","A194937-","C194938-","A194939-","C194940-","C194941-","G194942-","T194943-","C194944-","T194945-","C194946-","T194947-","T194948-","C194949-","C194950-","A194951-","C194952-","A194953-","G194954-","A194955-","T194956-","A194957-","A194958-","A194959-","T194960-","G194961-","C194962-","G194963-","A194964-","A194965-","C194966-","C194967-","C194968-","G194969-","T194970-","C194971-","G194972-","T194973-","A194974-","A194975-","C194976-","C194977-","A194978-","G194979-","C194980-","A194981-","A194982-","T194983-","A194984-","C194985-","A194986-","T194987-","T194988-","T194989-","A194990-","A194991-","C194992-","T194993-","A194994-","T194995-","A194996-","T194997-","C194998-","G194999-","A195000-","T195001-","G195002-","T195003-","G195004-","G195005-","A195006-","A195007-","A195008-","T195009-","T195010-","A195011-","A195012-","C195013-","C195014-","T195015-","G195016-","T195017-","A195018-","T195019-","C195020-","C195021-","A195022-","G195023-","T195024-","C195025-","A195026-","A195027-","C195028-","G195029-","A195030-","C195031-","A195032-","C195033-","A195034-","T195035-","C195036-","G195037-","T195038-","G195039-","T195040-","A195041-","C195042-","T195043-","C195044-","G195045-","G195046-","A195047-","C195048-","G195049-","A195050-","C195051-","C195052-","A195053-","C195054-","T195055-","A195056-","C195057-","C195058-","G195059-","G195060-","T195061-","C195062-","T195063-","C195064-","A195065-","G195066-","C195067-","G195068-","A195069-","A195070-","T195071-","C195072-","C195073-","A195074-","T195075-","C195076-","T195077-","C195078-","A195079-","A195080-","C195081-","G195082-","T195083-","C195084-","G195085-","G195086-","A195087-","A195088-","C195089-","T195090-","A195091-","A195092-","C195093-","T195094-","A195095-","T195096-","T195097-","A195098-","C195099-","C195100-","A195101-","T195102-","G195103-","A195104-","A195105-","T195106-","C195107-","A195108-","T195109-","A195110-","A195111-","A195112-","G195113-","A195114-","T195115-","T195116-","G195117-","T195118-","G195119-","A195120-","T195121-","C195122-","C195123-","A195124-","G195125-","T195126-","C195127-","T195128-","T195129-","T195130-","C195131-","G195132-","T195133-","G195134-","C195135-","A195136-","G195137-","A195138-","A195139-","T195140-","A195141-","C195142-","T195143-","T195144-","C195145-","T195146-","C195147-","T195148-","G195149-","T195150-","C195151-","C195152-","T195153-","T195154-","A195155-","A195156-","T195157-","A195158-","A195159-","T195160-","G195161-","T195162-","A195163-","G195164-","C195165-","A195166-","A195167-","C195168-","T195169-","T195170-","C195171-","A195172-","G195173-","G195174-","A195175-","T195176-","T195177-","C195178-","T195179-","T195180-","T195181-","A195182-","C195183-","A195184-","G195185-","G195186-","A195187-","G195188-","A195189-","A195190-","A195191-","A195192-","T195193-","A195194-","G195195-","A195196-","T195197-","A195198-","T195199-","C195200-","A195201-","G195202-","A195203-","A195204-","T195205-","A195206-","C195207-","T195208-","T195209-","C195210-","A195211-","A195212-","A195213-","G195214-","A195215-","T195216-","A195217-","T195218-","G195219-","T195220-","A195221-","C195222-","T195223-","C195224-","T195225-","G195226-","A195227-","A195228-","T195229-","T195230-","T195231-","C195232-","G195233-","A195234-","G195235-","A195236-","T195237-","T195238-","A195239-","A195240-","A195241-","T195242-","G195243-","T195244-","A195245-","A195246-","C195247-","A195248-","A195249-","C195250-","A195251-","A195252-","A195253-","G195254-","A195255-","T195256-","T195257-","C195258-","A195259-","T195260-","C195261-","T195262-","T195263-","C195264-","C195265-","A195266-","A195267-","A195268-","C195269-","A195270-","G195271-","T195272-","T195273-","A195274-","A195275-","C195276-","G195277-","A195278-","A195279-","A195280-","A195281-","C195282-","A195283-","A195284-","A195285-","G195286-","A195287-","A195288-","T195289-","G195290-","A195291-","T195292-","A195293-","C195294-","T195295-","A195296-","T195297-","C195298-","A195299-","T195300-","G195301-","C195302-","C195303-","G195304-","C195305-","A195306-","T195307-","T195308-","C195309-","A195310-","G195311-","A195312-","G195313-","A195314-","C195315-","G195316-","G195317-","T195318-","A195319-","A195320-","C195321-","T195322-","C195323-","T195324-","A195325-","G195326-","T195327-","G195328-","G195329-","G195330-","C195331-","G195332-","A195333-","C195334-","T195335-","G195336-","T195337-","C195338-","T195339-","A195340-","T195341-","C195342-","T195343-","A195344-","G195345-","C195346-","G195347-","T195348-","C195349-","G195350-","A195351-","C195352-","A195353-","T195354-","C195355-","T195356-","A195357-","C195358-","A195359-","T195360-","A195361-","C195362-","T195363-","A195364-","T195365-","A195366-","T195367-","A195368-","G195369-","T195370-","A195371-","A195372-","T195373-","A195374-","C195375-","C195376-","A195377-","A195378-","T195379-","A195380-","C195381-","T195382-","C195383-","A195384-","A195385-","G195386-","A195387-","C195388-","T195389-","A195390-","C195391-","G195392-","A195393-","A195394-","A195395-","A195396-","T195397-","G195398-","A195399-","T195400-","A195401-","C195402-","A195403-","A195404-","T195405-","C195406-","T195407-","C195408-","T195409-","T195410-","A195411-","T195412-","C195413-","A195414-","T195415-","A195416-","T195417-","G195418-","G195419-","G195420-","T195421-","A195422-","A195423-","T195424-","G195425-","T195426-","T195427-","C195428-","T195429-","C195430-","G195431-","A195432-","T195433-","G195434-","T195435-","C195436-","A195437-","A195438-","T195439-","A195440-","G195441-","C195442-","C195443-","A195444-","T195445-","A195446-","T195447-","G195448-","C195449-","C195450-","C195451-","G195452-","C195453-","T195454-","A195455-","G195456-","T195457-","T195458-","G195459-","C195460-","G195461-","A195462-","T195463-","A195464-","T195465-","A195466-","C195467-","A195468-","T195469-","A195470-","A195471-","A195472-","C195473-","T195474-","G195475-","A195476-","T195477-","C195478-","A195479-","C195480-","T195481-","A195482-","A195483-","T195484-","T195485-","C195486-","C195487-","C195488-","A195489-","G195490-","A195491-","A195492-","T195493-","C195494-","C195495-","C195496-","A195497-","C195498-","C195499-","C195500-","A195501-","C195502-","T195503-","T195504-","A195505-","T195506-","A195507-","G195508-","T195509-","A195510-","A195511-","G195512-","T195513-","T195514-","T195515-","T195516-","T195517-","T195518-","T195519-","A195520-","C195521-","C195522-","T195523-","A195524-","T195525-","A195526-","A195527-","A195528-","T195529-","A195530-","A195531-","T195532-","A195533-","A195534-","A195535-","T195536-","A195537-","C195538-","A195539-","A195540-","T195541-","A195542-","A195543-","T195544-","T195545-","A195546-","A195547-","T195548-","T195549-","T195550-","C195551-","T195552-","C195553-","G195554-","T195555-","A195556-","A195557-","A195558-","A195559-","G195560-","T195561-","A195562-","G195563-","A195564-","A195565-","A195566-","A195567-","T195568-","A195569-","T195570-","A195571-","T195572-","T195573-","C195574-","T195575-","A195576-","A195577-","T195578-","T195579-","T195580-","A195581-","T195582-","T195583-","A195584-","T195585-","A195586-","T195587-","G195588-","G195589-","T195590-","A195591-","A195592-","G195593-","A195594-","A195595-","A195596-","G195597-","T195598-","A195599-","G195600-","A195601-","A195602-","T195603-","C195604-","A195605-","T195606-","C195607-","T195608-","A195609-","G195610-","A195611-","A195612-","C195613-","A195614-","G195615-","T195616-","A195617-","A195618-","T195619-","C195620-","A195621-","A195622-","T195623-","C195624-","A195625-","A195626-","T195627-","A195628-","G195629-","C195630-","A195631-","A195632-","T195633-","C195634-","A195635-","T195636-","G195637-","A195638-","A195639-","A195640-","C195641-","A195642-","A195643-","T195644-","A195645-","T195646-","A195647-","T195648-","T195649-","G195650-","T195651-","C195652-","C195653-","T195654-","G195655-","G195656-","C195657-","A195658-","T195659-","G195660-","C195661-","A195662-","T195663-","G195664-","T195665-","G195666-","C195667-","C195668-","T195669-","A195670-","G195671-","T195672-","G195673-","G195674-","C195675-","A195676-","G195677-","C195678-","T195679-","G195680-","C195681-","T195682-","A195683-","T195684-","G195685-","C195686-","C195687-","T195688-","A195689-","C195690-","T195691-","A195692-","G195693-","T195694-","C195695-","T195696-","T195697-","C195698-","A195699-","A195700-","C195701-","A195702-","A195703-","T195704-","C195705-","T195706-","T195707-","C195708-","A195709-","T195710-","C195711-","C195712-","T195713-","C195714-","G195715-","T195716-","G195717-","T195718-","A195719-","C195720-","T195721-","G195722-","A195723-","A195724-","G195725-","A195726-","A195727-","G195728-","A195729-","A195730-","A195731-","A195732-","C195733-","A195734-","A195735-","A195736-","C195737-","A195738-","T195739-","C195740-","A195741-","T195742-","A195743-","T195744-","G195745-","G195746-","G195747-","A195748-","A195749-","T195750-","C195751-","G195752-","A195753-","T195754-","G195755-","T195756-","T195757-","A195758-","T195759-","T195760-","A195761-","T195762-","C195763-","A195764-","A195765-","A195766-","G195767-","T195768-","C195769-","A195770-","C195771-","A195772-","A195773-","A195774-","G195775-","C195776-","A195777-","A195778-","G195779-","A195780-","C195781-","C195782-","A195783-","A195784-","A195785-","C195786-","A195787-","C195788-","C195789-","G195790-","A195791-","C195792-","C195793-","A195794-","A195795-","T195796-","G195797-","A195798-","T195799-","A195800-","A195801-","G195802-","A195803-","T195804-","T195805-","T195806-","G195807-","T195808-","C195809-","A195810-","A195811-","T195812-","C195813-","C195814-","G195815-","T195816-","A195817-","A195818-","C195819-","G195820-","G195821-","A195822-","A195823-","G195824-","T195825-","T195826-","A195827-","C195828-","A195829-","G195830-","A195831-","G195832-","A195833-","C195834-","C195835-","G195836-","A195837-","A195838-","G195839-","A195840-","T195841-","G195842-","A195843-","T195844-","G195845-","A195846-","G195847-","G195848-","T195849-","A195850-","T195851-","C195852-","C195853-","G195854-","A195855-","A195856-","G195857-","A195858-","A195859-","G195860-","T195861-","T195862-","G195863-","T195864-","A195865-","A195866-","A195867-","A195868-","G195869-","G195870-","A195871-","G195872-","A195873-","T195874-","C195875-","C195876-","C195877-","A195878-","C195879-","C195880-","A195881-","C195882-","T195883-","T195884-","A195885-","T195886-","T195887-","A195888-","C195889-","A195890-","C195891-","T195892-","A195893-","T195894-","C195895-","G195896-","T195897-","C195898-","G195899-","G195900-","T195901-","G195902-","C195903-","G195904-","G195905-","G195906-","T195907-","C195908-","T195909-","T195910-","A195911-","A195912-","C195913-","A195914-","T195915-","G195916-","A195917-","A195918-","C195919-","T195920-","T195921-","T195922-","G195923-","G195924-","A195925-","T195926-","T195927-","C195928-","A195929-","C195930-","C195931-","A195932-","A195933-","A195934-","T195935-","G195936-","C195937-","C195938-","C195939-","A195940-","A195941-","A195942-","G195943-","A195944-","T195945-","T195946-","T195947-","T195948-","A195949-","T195950-","C195951-","C195952-","A195953-","T195954-","C195955-","T195956-","C195957-","C195958-","G195959-","A195960-","A195961-","T195962-","C195963-","C195964-","T195965-","C195966-","T195967-","G195968-","A195969-","T195970-","G195971-","G195972-","A195973-","A195974-","A195975-","C195976-","A195977-","C195978-","T195979-","G195980-","T195981-","G195982-","A195983-","A195984-","T195985-","A195986-","C195987-","T195988-","A195989-","G195990-","A195991-","T195992-","T195993-","G195994-","T195995-","C195996-","C195997-","A195998-","G195999-","C196000-","G196001-","T196002-","G196003-","T196004-","C196005-","A196006-","C196007-","C196008-","G196009-","G196010-","G196011-","A196012-","C196013-","A196014-","A196015-","G196016-","G196017-","T196018-","A196019-","A196020-","G196021-","G196022-","A196023-","C196024-","T196025-","C196026-","T196027-","C196028-","C196029-","C196030-","G196031-","C196032-","G196033-","A196034-","T196035-","C196036-","A196037-","C196038-","G196039-","C196040-","G196041-","T196042-","G196043-","A196044-","A196045-","G196046-","A196047-","A196048-","G196049-","C196050-","T196051-","C196052-","T196053-","G196054-","G196055-","C196056-","T196057-","A196058-","T196059-","G196060-","A196061-","T196062-","C196063-","A196064-","A196065-","A196066-","G196067-","A196068-","C196069-","T196070-","G196071-","T196072-","G196073-","A196074-","G196075-","A196076-","T196077-","G196078-","T196079-","C196080-","T196081-","A196082-","T196083-","C196084-","G196085-","A196086-","C196087-","A196088-","T196089-","C196090-","A196091-","G196092-","A196093-","T196094-","G196095-","T196096-","A196097-","G196098-","C196099-","G196100-","A196101-","A196102-","G196103-","A196104-","A196105-","G196106-","A196107-","G196108-","A196109-","A196110-","A196111-","G196112-","A196113-","C196114-","A196115-","G196116-","T196117-","G196118-","A196119-","C196120-","A196121-","T196122-","C196123-","A196124-","A196125-","G196126-","A196127-","C196128-","C196129-","C196130-","A196131-","T196132-","C196133-","C196134-","A196135-","G196136-","T196137-","A196138-","C196139-","T196140-","T196141-","G196142-","G196143-","G196144-","T196145-","C196146-","T196147-","A196148-","A196149-","C196150-","A196151-","T196152-","C196153-","T196154-","C196155-","A196156-","C196157-","A196158-","T196159-","A196160-","A196161-","G196162-","A196163-","A196164-","A196165-","G196166-","T196167-","G196168-","A196169-","G196170-","T196171-","T196172-","A196173-","C196174-","A196175-","A196176-","A196177-","G196178-","A196179-","T196180-","A196181-","T196182-","C196183-","A196184-","T196185-","C196186-","G196187-","G196188-","T196189-","T196190-","C196191-","A196192-","A196193-","C196194-","G196195-","A196196-","T196197-","C196198-","G196199-","T196200-","T196201-","G196202-","A196203-","T196204-","A196205-","C196206-","A196207-","A196208-","A196209-","A196210-","T196211-","G196212-","T196213-","G196214-","T196215-","C196216-","A196217-","A196218-","G196219-","A196220-","A196221-","C196222-","C196223-","T196224-","A196225-","G196226-","A196227-","G196228-","T196229-","T196230-","T196231-","A196232-","G196233-","C196234-","G196235-","T196236-","A196237-","C196238-","G196239-","T196240-","A196241-","T196242-","C196243-","G196244-","G196245-","A196246-","G196247-","A196248-","C196249-","A196250-","T196251-","G196252-","T196253-","G196254-","T196255-","G196256-","A196257-","G196258-","G196259-","A196260-","A196261-","T196262-","C196263-","A196264-","T196265-","C196266-","T196267-","G196268-","A196269-","A196270-","C196271-","T196272-","T196273-","G196274-","A196275-","A196276-","G196277-","T196278-","C196279-","A196280-","A196281-","G196282-","G196283-","A196284-","T196285-","G196286-","G196287-","A196288-","T196289-","T196290-","C196291-","A196292-","A196293-","G196294-","T196295-","A196296-","T196297-","G196298-","T196299-","C196300-","G196301-","A196302-","C196303-","G196304-","G196305-","A196306-","T196307-","C196308-","G196309-","G196310-","C196311-","A196312-","T196313-","C196314-","T196315-","G196316-","A196317-","A196318-","G196319-","G196320-","T196321-","G196322-","C196323-","A196324-","A196325-","C196326-","C196327-","G196328-","A196329-","T196330-","G196331-","A196332-","T196333-","A196334-","C196335-","T196336-","T196337-","C196338-","A196339-","C196340-","T196341-","C196342-","A196343-","T196344-","C196345-","G196346-","A196347-","T196348-","T196349-","C196350-","A196351-","A196352-","C196353-","A196354-","A196355-","A196356-","A196357-","C196358-","T196359-","C196360-","A196361-","A196362-","A196363-","G196364-","C196365-","A196366-","T196367-","G196368-","T196369-","G196370-","T196371-","C196372-","T196373-","G196374-","A196375-","A196376-","T196377-","C196378-","G196379-","A196380-","T196381-","A196382-","A196383-","C196384-","T196385-","C196386-","T196387-","A196388-","T196389-","T196390-","C196391-","A196392-","T196393-","C196394-","T196395-","G196396-","A196397-","A196398-","A196399-","A196400-","T196401-","G196402-","G196403-","A196404-","T196405-","G196406-","A196407-","G196408-","T196409-","T196410-","G196411-","G196412-","G196413-","T196414-","T196415-","A196416-","A196417-","T196418-","C196419-","G196420-","A196421-","A196422-","C196423-","G196424-","A196425-","T196426-","T196427-","C196428-","A196429-","G196430-","A196431-","C196432-","A196433-","C196434-","C196435-","G196436-","C196437-","A196438-","C196439-","C196440-","A196441-","C196442-"],"OPG038":["H173Y"],"OPG099":["D124N"],"OPG155":["D119N"]},"labels":{"aa":"OPG038: H173Y; OPG099: D124N; OPG155: D119N"}}},{"name":"NODE_0000261","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C121104T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-196615A"],"OPG138":["R10K"]},"labels":{"aa":"OPG138: R10K"}},"children":[{"name":"OR264427","node_attrs":{"div":5,"accession":"OR264427","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264427/2022-05-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-05-19"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"4_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G57661A","A118917C","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C187452T"],"OPG077":["S308L"],"OPG136":["I224S"]},"labels":{"aa":"OPG077: S308L; OPG136: I224S"}}},{"name":"OR264430","node_attrs":{"div":3,"accession":"OR264430","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264430/2022-09-05"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-09-05"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"51_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C15582T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000262","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C190276T"],"OPG044":["K147-"]},"labels":{"aa":"OPG044: K147-"}},"children":[{"name":"NODE_0000263","node_attrs":{"div":7,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T607-","C7034T","A28529-","A28530-","G70190A","G144895A","G187827A","A196615-"],"OPG089":["E109K"]},"labels":{"aa":"OPG089: E109K"}},"children":[{"name":"OR264452","node_attrs":{"div":7,"accession":"OR264452","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264452/2022-08-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-25"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"66_C"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-"]}}},{"name":"OR264436","node_attrs":{"div":7,"accession":"OR264436","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264436/2022-08-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-09"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"55_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-28529A","-28530A","T76084-","T76085-"],"OPG044":["-147K"]},"labels":{"aa":"OPG044: -147K"}}},{"name":"OR264369","node_attrs":{"div":7,"accession":"OR264369","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264369/2022-08-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-08"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"16_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000264","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C134102T"]}},"children":[{"name":"OR264431","node_attrs":{"div":4,"accession":"OR264431","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264431/2022-08-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-02"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"52_B"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"OPG044":["-147K"]},"labels":{"aa":"OPG044: -147K"}}},{"name":"NODE_0000265","node_attrs":{"div":5,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T607-","A28529-","A28530-","T80846-","T80847-","T133101-","T133102-","G177009A","A196615-"],"OPG205":["E452K"]},"labels":{"aa":"OPG205: E452K"}},"children":[{"name":"OR264448","node_attrs":{"div":5,"accession":"OR264448","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264448/2022-08-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-23"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"63_E"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-28529A","-28530A","-133101T","-133102T","A138474-","T170904-"],"OPG044":["-147K"]},"labels":{"aa":"OPG044: -147K"}}},{"name":"OR264380","node_attrs":{"div":5,"accession":"OR264380","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264380/2022-08-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-22"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"25_D"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T76084-","T76085-","T133097-","T133098-","T133099-","T133100-","A152675-","A152676-"]}}},{"name":"OR264366","node_attrs":{"div":5,"accession":"OR264366","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264366/2022-08-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-16"},"lineage":{"value":"B.1"},"country":{"value":"Australia"},"strain":{"value":"14_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-80846T","-80847T"]}}}]}]}]}]},{"name":"NODE_0000266","node_attrs":{"div":3,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C164385T","C187620T"]},"labels":{"clade":"B.1.20"}},"children":[{"name":"OQ320441","node_attrs":{"div":3,"accession":"OQ320441","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"strain_display":{"value":"USA/OQ320441/2022-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-10-XX"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_TX0040"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","T133102-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-196615A"]}}},{"name":"NODE_0000267","node_attrs":{"div":4,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T602-","T603-","T604-","T605-","T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177398A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","C179190-","A179191-","T179192-","T179193-","A196610-","A196611-","A196612-","A196613-","A196614-"]}},"children":[{"name":"OQ427126","node_attrs":{"div":6,"accession":"OQ427126","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"strain_display":{"value":"USA/OQ427126/2022-11-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-11-XX"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_TX0045"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G36027A","C72221T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-"],"OPG055":["R353C"],"OPG092":["E243K"]},"labels":{"aa":"OPG055: R353C; OPG092: E243K"}}},{"name":"OQ918695","node_attrs":{"div":4,"accession":"OQ918695","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"strain_display":{"value":"USA/OQ918695/2023-02-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"date":{"value":"2023-02-07"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00484/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR464208","node_attrs":{"div":6,"accession":"OR464208","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"strain_display":{"value":"USA/OR464208/2022-12-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"CDC, DHCPP-PRB"},"date":{"value":"2022-12-XX"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV_USA_2022_TX0055"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G129761A","G150577-","A150578-","T150579-","A150580-","T150581-","G150582-","A150583-","T150584-","G150585-","T165597C","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A"],"OPG151":["D280N"],"OPG190":["V159A"]},"labels":{"aa":"OPG151: D280N; OPG190: V159A"}}},{"name":"NODE_0000268","node_attrs":{"div":5,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C177899T","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-"]}},"children":[{"name":"OR500006","node_attrs":{"div":5,"accession":"OR500006","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR500006/2023-03-24"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-03-24"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00530/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179145T","T179244-"]}}},{"name":"OR499972","node_attrs":{"div":7,"accession":"OR499972","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499972/2023-04-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-04-25"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00515/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G18919A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G187517A"]}}},{"name":"OR499966","node_attrs":{"div":6,"accession":"OR499966","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499966/2023-03-31"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-03-31"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00509/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G115293A"],"OPG133":["A135V"]},"labels":{"aa":"OPG133: A135V"}}},{"name":"NODE_0000269","node_attrs":{"div":6,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-602T","G146690A","-196610A"],"OPG170":["S30F"]},"labels":{"aa":"OPG170: S30F"}},"children":[{"name":"OR499956","node_attrs":{"div":6,"accession":"OR499956","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499956/2023-04-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-04-30"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00499/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C661-","A662-","C663-","T196633-","C196634-","T196635-"]}}},{"name":"OR499951","node_attrs":{"div":6,"accession":"OR499951","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499951/2023-04-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-04-30"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00494/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G196724-","A196725-","G196726-"]}}},{"name":"OR499949","node_attrs":{"div":6,"accession":"OR499949","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499949/2023-03-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-03-30"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00492/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A196713-","T196714-","A196715-"]}}},{"name":"NODE_0000270","node_attrs":{"div":8,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C159608T","G163900-","A163901-","A163902-","T163903-","C163904-","A163905-","G168964A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A192393C","G192396A","A192402G"],"OPG185":["S231F"],"OPG189":["E190-","S191-"]},"labels":{"aa":"OPG185: S231F; OPG189: E190-, S191-"}},"children":[{"name":"OR665162","node_attrs":{"div":8,"accession":"OR665162","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OR665162/2023-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-09-XX"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-097833/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000271","node_attrs":{"div":9,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G141131A"]}},"children":[{"name":"OR665165","node_attrs":{"div":10,"accession":"OR665165","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OR665165/2023-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-09-XX"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-097301/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G177918A"],"OPG205":["D755N"]},"labels":{"aa":"OPG205: D755N"}}},{"name":"OR665163","node_attrs":{"div":10,"accession":"OR665163","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OR665163/2023-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-09-XX"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-097798/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A80466G"],"OPG103":["N156D"]},"labels":{"aa":"OPG103: N156D"}}},{"name":"OR665164","node_attrs":{"div":9,"accession":"OR665164","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OR665164/2023-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-09-XX"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-098659/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000272","node_attrs":{"div":6,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C22349T"],"OPG037":["E29K"]},"labels":{"aa":"OPG037: E29K"}},"children":[{"name":"OR499977","node_attrs":{"div":10,"accession":"OR499977","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499977/2023-05-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-05-23"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00520/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G61484A","G84462A","C90750T","C113477T","-179145T","T179244-","T196633-","C196634-","T196635-"],"OPG080":["H179Y"],"OPG105":["D1113N"],"OPG132":["E22K"]},"labels":{"aa":"OPG080: H179Y; OPG105: D1113N; OPG132: E22K"}}},{"name":"NODE_0000273","node_attrs":{"div":10,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C15718T","C83753T","G98119A","C113363T"],"OPG117":["E691K"],"OPG132":["D60N"]},"labels":{"aa":"OPG117: E691K; OPG132: D60N"}},"children":[{"name":"OR643712","node_attrs":{"div":11,"accession":"OR643712","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR643712/2023-07-31"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-07-31"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00556/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G36246A"]}}},{"name":"OR643713","node_attrs":{"div":10,"accession":"OR643713","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR643713/2023-06-29"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-06-29"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00557/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T46648-"]}}},{"name":"OR643706","node_attrs":{"div":11,"accession":"OR643706","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR643706/2023-06-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-06-27"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00551/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C651-","A652-","T653-","G126514A"],"OPG148":["D177N"]},"labels":{"aa":"OPG148: D177N"}}},{"name":"OR643707","node_attrs":{"div":13,"accession":"OR643707","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR643707/2023-07-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-07-27"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00552/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C4977T","C15162T","G88847A","-179145T","T179244-","G192233A"],"OPG015":["E394K"],"OPG015_dup":["E394K"],"OPG025":["D36N"],"OPG109":["P201S"]},"labels":{"aa":"OPG015: E394K; OPG015_dup: E394K; OPG025: D36N; OPG109: P201S"}}},{"name":"OR499991","node_attrs":{"div":11,"accession":"OR499991","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499991/2023-06-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-06-28"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00535/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C60554T","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG080":["E489K"]},"labels":{"aa":"OPG080: E489K"}}},{"name":"OR499981","node_attrs":{"div":10,"accession":"OR499981","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499981/2023-06-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-06-16"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00524/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179145T","T179244-"]}}},{"name":"OR499975","node_attrs":{"div":10,"accession":"OR499975","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499975/2023-06-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-06-21"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00518/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR473614","node_attrs":{"div":11,"accession":"OR473614","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR473614/2023-06-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-06-27"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0077/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G164230A"],"OPG189":["E300K"]},"labels":{"aa":"OPG189: E300K"}}},{"name":"NODE_0000274","node_attrs":{"div":13,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C11710T","G41336A","G155611A"]}},"children":[{"name":"OR643709","node_attrs":{"div":13,"accession":"OR643709","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR643709/2023-07-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-07-30"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00554/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR643703","node_attrs":{"div":13,"accession":"OR643703","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR643703/2023-08-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-08-09"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00561/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000275","node_attrs":{"div":15,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C629-","C630-","A631-","A632-","G633-","A634-","G635-","A636-","G25213A","C168713T","-196610A","-196611A","-196612A","-196613A","-196614A"],"OPG040":["S89F"],"OPG195":["Q162*"]},"labels":{"aa":"OPG040: S89F; OPG195: Q162*"}},"children":[{"name":"OR643710","node_attrs":{"div":16,"accession":"OR643710","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR643710/2023-08-14"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-08-14"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00564/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C170130T"]}}},{"name":"OR643704","node_attrs":{"div":15,"accession":"OR643704","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR643704/2023-08-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-08-07"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00562/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000276","node_attrs":{"div":6,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T164946C"]}},"children":[{"name":"OR160416","node_attrs":{"div":10,"accession":"OR160416","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR160416/2023-05-17"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-05-17"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0058/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G7637A","G36409A","C101983T","G186105A"],"OPG019":["D20N"],"OPG121":["S65L"],"OPG210":["E1584K"]},"labels":{"aa":"OPG019: D20N; OPG121: S65L; OPG210: E1584K"}}},{"name":"NODE_0000277","node_attrs":{"div":7,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C20453T"]}},"children":[{"name":"OR449306","node_attrs":{"div":7,"accession":"OR449306","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR449306/2023-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2023-07-XX"},"lineage":{"value":"B.1.20"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2023/RKI1020"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-602T","-603T","-604T","-605T","-606T","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"]}}},{"name":"OR421483","node_attrs":{"div":7,"accession":"OR421483","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR421483/2023-05-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-05-16"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0045/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR421480","node_attrs":{"div":7,"accession":"OR421480","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR421480/2023-05-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-05-07"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0023/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR421478","node_attrs":{"div":7,"accession":"OR421478","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR421478/2023-04-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-04-27"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0020/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR257451","node_attrs":{"div":7,"accession":"OR257451","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR257451/2023-05-31"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-05-31"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0061/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR574872","node_attrs":{"div":7,"accession":"OR574872","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR574872/2023-08-15"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-08-15"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0097/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR574870","node_attrs":{"div":12,"accession":"OR574870","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR574870/2023-08-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-08-03"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0095/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G17038A","G34502A","C86402T","G105411A","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","C177946T"],"OPG029":["S11F"],"OPG108":["E220K"],"OPG153":["D384-","D385-"],"OPG205":["T764I"]},"labels":{"aa":"OPG029: S11F; OPG108: E220K; OPG153: D384-, D385-; OPG205: T764I"}}},{"name":"OR643699","node_attrs":{"div":8,"accession":"OR643699","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR643699/2023-07-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-07-28"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00550/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G3804T","C193406A"]}}},{"name":"OR574864","node_attrs":{"div":7,"accession":"OR574864","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR574864/2023-05-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-05-16"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0055/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR574865","node_attrs":{"div":7,"accession":"OR574865","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR574865/2023-06-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-06-01"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0065/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C169399T"]}}},{"name":"OR574861","node_attrs":{"div":7,"accession":"OR574861","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR574861/2023-05-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-05-13"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0052/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR574863","node_attrs":{"div":7,"accession":"OR574863","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR574863/2023-05-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-05-16"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0054/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G625-","A626-","G627-"]}}},{"name":"OR574860","node_attrs":{"div":7,"accession":"OR574860","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR574860/2023-05-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-05-12"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0051/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OR500005","node_attrs":{"div":8,"accession":"OR500005","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR500005/2023-07-26"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-07-26"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00549/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","G18504A","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","-179145T","T179244-"]}}},{"name":"OR499997","node_attrs":{"div":7,"accession":"OR499997","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499997/2023-06-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-06-28"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00541/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR499955","node_attrs":{"div":7,"accession":"OR499955","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499955/2023-04-24"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-04-24"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00498/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR499954","node_attrs":{"div":7,"accession":"OR499954","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499954/2023-04-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-04-28"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00497/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000278","node_attrs":{"div":8,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C2313T","G194897A"],"OPG002":["D147N"],"OPG002_dup":["D147N"]},"labels":{"aa":"OPG002: D147N; OPG002_dup: D147N"}},"children":[{"name":"OR160420","node_attrs":{"div":8,"accession":"OR160420","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR160420/2023-05-15"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-05-15"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-052-0039/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000279","node_attrs":{"div":9,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G51378A","T196676-","G196677-","T196678-"]}},"children":[{"name":"OR500002","node_attrs":{"div":10,"accession":"OR500002","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR500002/2023-06-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-06-12"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00546/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A11160G"],"OPG023":["F581L"]},"labels":{"aa":"OPG023: F581L"}}},{"name":"OR499998","node_attrs":{"div":9,"accession":"OR499998","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR499998/2023-06-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-06-22"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00542/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR500003","node_attrs":{"div":9,"accession":"OR500003","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR500003/2023-06-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-06-12"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00547/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A140155T","A140156G"],"OPG159":["N130C"]},"labels":{"aa":"OPG159: N130C"}}}]}]},{"name":"NODE_0000280","node_attrs":{"div":8,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C180618T"],"OPG209":["S34L"]},"labels":{"aa":"OPG209: S34L"}},"children":[{"name":"OR353591","node_attrs":{"div":15,"accession":"OR353591","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"strain_display":{"value":"USA/OR353591/2023-06-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"Minnesota Department of Health, Public Health Laboratory"},"date":{"value":"2023-06-07"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"MN-MDH-MPXV_0081"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A2591G","A3111G","A3522G","T3818C","C14589T","T76087-","C134847T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C183826T","T194619C","T195948C"],"OPG001_dup":["L105S"],"OPG002":["F54S"],"OPG002_dup":["F54S"],"OPG003":["N264D"],"OPG025":["D227N"],"OPG197":["T34-","D35-"],"OPG210":["S824F"]},"labels":{"aa":"OPG001_dup: L105S; OPG002: F54S; OPG002_dup: F54S; OPG003: N264D; OPG025: D227N; OPG197: T34-, D35-; OPG210: S824F"}}},{"name":"OR574869","node_attrs":{"div":9,"accession":"OR574869","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR574869/2023-06-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-06-12"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0073/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-602T","-603T","-604T","-605T","-606T","C98128T"],"OPG117":["P694S"]},"labels":{"aa":"OPG117: P694S"}}},{"name":"OR473622","node_attrs":{"div":8,"accession":"OR473622","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR473622/2023-06-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-06-27"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0076/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR473616","node_attrs":{"div":8,"accession":"OR473616","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR473616/2023-07-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-07-12"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0084/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000281","node_attrs":{"div":9,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-602T","-603T","-604T","T765-","T766-","C767-","C174050T"]}},"children":[{"name":"OR725697","node_attrs":{"div":11,"accession":"OR725697","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR725697/2023-09-06"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-09-06"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0107/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G113508A","C136791T"],"OPG153":["E293K"]},"labels":{"aa":"OPG153: E293K"}}},{"name":"OR473617","node_attrs":{"div":9,"accession":"OR473617","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR473617/2023-07-11"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-07-11"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0085/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR473613","node_attrs":{"div":9,"accession":"OR473613","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR473613/2023-07-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-07-21"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0089/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T196627-","C196628-","T196629-"]}}},{"name":"NODE_0000282","node_attrs":{"div":10,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C25865T"],"OPG204":["S276L"]},"labels":{"aa":"OPG204: S276L"}},"children":[{"name":"OR574871","node_attrs":{"div":10,"accession":"OR574871","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR574871/2023-08-10"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-08-10"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0096/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR502626","node_attrs":{"div":12,"accession":"OR502626","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR502626/2023-07-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-07-23"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0091/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C5912T","C56140T","C175358T","G191298A"],"OPG015":["R82K"],"OPG015_dup":["R82K"],"OPG074":["R329K"]},"labels":{"aa":"OPG015: R82K; OPG015_dup: R82K; OPG074: R329K"}}}]},{"name":"NODE_0000283","node_attrs":{"div":10,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C105798T"]}},"children":[{"name":"OR725693","node_attrs":{"div":11,"accession":"OR725693","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR725693/2023-08-18"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-08-18"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0099/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G148126A","T196633-","C196634-","T196635-"]}}},{"name":"OR502628","node_attrs":{"div":10,"accession":"OR502628","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR502628/2023-07-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-07-23"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-052-0092/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR502627","node_attrs":{"div":11,"accession":"OR502627","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR502627/2023-07-26"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-07-26"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0094/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C43803T","A196723-","G196724-","A196725-"],"OPG064":["G699E"]},"labels":{"aa":"OPG064: G699E"}}},{"name":"OR473612","node_attrs":{"div":11,"accession":"OR473612","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"strain_display":{"value":"USA/OR473612/2023-07-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"date":{"value":"2023-07-03"},"lineage":{"value":"B.1.20"},"country":{"value":"USA"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0078/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G157842A"]}}}]}]}]}]}]}]}]}]}]},{"name":"NODE_0000284","node_attrs":{"div":1,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179217C","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G190660A"],"OPG016":["R84K"]},"labels":{"aa":"OPG016: R84K","clade":"B.1.3"}},"children":[{"name":"ON983168","node_attrs":{"div":1,"accession":"ON983168","author":{"author":"Chmel,M.,Pajer,P.,Nagy,A.,Zlamal,M.,Jirincova,H.,Dresler,J.,Bartos,O.","value":"Chmel,M.,Pajer,P.,Nagy,A.,Zlamal,M.,Jirincova,H.,Dresler,J.,Bartos,O."},"strain_display":{"value":"Czech Republic/ON983168/2022-04-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"Military Heatlh Institute, Military Heatlh Institute in Prague"},"date":{"value":"2022-04-28"},"lineage":{"value":"B.1.3"},"country":{"value":"Czech Republic"},"strain":{"value":"MPxV/Prague_001/2022/flye_medaka"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T80849-","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A"]}}},{"name":"OP205116","node_attrs":{"div":6,"accession":"OP205116","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205116/2022-07-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-07-07"},"lineage":{"value":"B.1.3"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000158"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C17196T","C39898T","C148933T","G171318A","C175241T","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A"],"OPG057":["D100N"],"OPG174":["E155K"],"OPG199":["E111K"],"OPG204":["S237L"]},"labels":{"aa":"OPG057: D100N; OPG174: E155K; OPG199: E111K; OPG204: S237L"}}},{"name":"OP414383","node_attrs":{"div":1,"accession":"OP414383","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP414383/2022-05-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-05-23"},"lineage":{"value":"B.1.3"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0356/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A666-","T667-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","C179217-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP536804","node_attrs":{"div":3,"accession":"OP536804","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536804/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"United Kingdom"},"strain":{"value":"9000432"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C6423A","C135775T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","T190787-","A196614-"]}}},{"name":"OP536795","node_attrs":{"div":1,"accession":"OP536795","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP536795/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"United Kingdom"},"strain":{"value":"9000421"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A"]}}},{"name":"OP727821","node_attrs":{"div":1,"accession":"OP727821","author":{"author":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K.","value":"Berens-Riha,N.,De Block,T.,Rutgers,J.,Van Gestel,L.,Hens,M.,Kenyon,C.,Soentjens,P.,Van Griensven,J.,Brosius,I.,Arien,K.,Van Esbroeck,M.,Rezende,A.M.,Vercauteren,K."},"strain_display":{"value":"Belgium/OP727821/2022-08-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-08-27"},"lineage":{"value":"B.1.3"},"country":{"value":"Belgium"},"strain":{"value":"PrEV_case_1"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A173314-","T173315-","A173316-","T173317-","C179190-","C179217-"]}}},{"name":"OR350452","node_attrs":{"div":2,"accession":"OR350452","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"strain_display":{"value":"USA/OR350452/2022-08-15"},"host":{"value":"Homo sapiens"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"date":{"value":"2022-08-15"},"lineage":{"value":"B.1.3"},"country":{"value":"USA"},"strain":{"value":"MPXV22/human/USA-NE-166"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C33971T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG052":["D9N"]},"labels":{"aa":"OPG052: D9N"}}},{"name":"NODE_0000285","node_attrs":{"div":2,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C64426T"]}},"children":[{"name":"OQ721953","node_attrs":{"div":9,"accession":"OQ721953","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"strain_display":{"value":"Taiwan/OQ721953/2023-03-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"date":{"value":"2023-03-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"Taiwan"},"strain":{"value":"MPXV/human/Taiwan/110-525030/2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C166940T","T177665A","A177666T","A177667T","G178104T","G178290T","T178629A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","C179217-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G196412A"],"OPG205":["N670K","N671F"]},"labels":{"aa":"OPG205: N670K, N671F"}}},{"name":"NODE_0000286","node_attrs":{"div":3,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G55133A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A"],"OPG074":["R665C"]},"labels":{"aa":"OPG074: R665C"}},"children":[{"name":"ON792320","node_attrs":{"div":4,"accession":"ON792320","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"strain_display":{"value":"Switzerland/ON792320/2022-06-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"date":{"value":"2022-06-01"},"lineage":{"value":"B.1.3"},"country":{"value":"Switzerland"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba6449f/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G159376A"],"OPG185":["D154N"]},"labels":{"aa":"OPG185: D154N"}}},{"name":"ON782054","node_attrs":{"div":5,"accession":"ON782054","author":{"author":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"strain_display":{"value":"Spain/ON782054/2022-05-31"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"date":{"value":"2022-05-31"},"lineage":{"value":"B.1.3"},"country":{"value":"Spain"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0001a/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G50337A","A122238T","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A169759G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A193392G","T193688C","T194099C","T194619C","T195948C","-196615A"],"OPG001_dup":["L105S"],"OPG002_dup":["F54S"],"OPG003_dup":["N264D"],"OPG069":["G118R"],"OPG143":["S360T"]},"labels":{"aa":"OPG001_dup: L105S; OPG002_dup: F54S; OPG003_dup: N264D; OPG069: G118R; OPG143: S360T"}}},{"name":"ON782055","node_attrs":{"div":5,"accession":"ON782055","author":{"author":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"strain_display":{"value":"Spain/ON782055/2022-05-31"},"host":{"value":"Homo sapiens"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"date":{"value":"2022-05-31"},"lineage":{"value":"B.1.3"},"country":{"value":"Spain"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0001b/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A48265T","C48296G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG068":["D22V"]},"labels":{"aa":"OPG068: D22V"}}},{"name":"ON782021","node_attrs":{"div":3,"accession":"ON782021","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O."},"strain_display":{"value":"Finland/ON782021/2022-05-24"},"host":{"value":"Homo sapiens"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"date":{"value":"2022-05-24"},"lineage":{"value":"B.1.3"},"country":{"value":"Finland"},"strain":{"value":"MPX-37/Finland/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"ON622722","node_attrs":{"div":4,"accession":"ON622722","strain_display":{"value":"France/ON622722/2022-05-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"Virology, GENomique EPIdemiologique das maladies Infectieuses, France"},"date":{"value":"2022-05-22"},"lineage":{"value":"B.1.3"},"country":{"value":"France"},"strain":{"value":"MPXV_FR_HCL0001_2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C109627A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG129":["A460S"]},"labels":{"aa":"OPG129: A460S"}}},{"name":"OP205067","node_attrs":{"div":3,"accession":"OP205067","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"strain_display":{"value":"United Kingdom/OP205067/2022-05-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"UKHSA, Research and Evaluation"},"date":{"value":"2022-05-27"},"lineage":{"value":"B.1.3"},"country":{"value":"United Kingdom"},"strain":{"value":"MPXV_UK_2022_9000061"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-196615A"]}}},{"name":"OP484692","node_attrs":{"div":7,"accession":"OP484692","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OP484692/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-09-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI371"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G101152A","G124855T","G141131A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C180490G"],"OPG145":["E303D"]},"labels":{"aa":"OPG145: E303D"}}},{"name":"OP605568","node_attrs":{"div":6,"accession":"OP605568","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605568/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-26-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C12426T","C44716T","C141194T","A196614-"],"OPG023":["E159K"],"OPG064":["E395K"]},"labels":{"aa":"OPG023: E159K; OPG064: E395K"}}},{"name":"OP555585","node_attrs":{"div":3,"accession":"OP555585","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555585/2022-08-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-08-16"},"lineage":{"value":"B.1.3"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0514/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP555633","node_attrs":{"div":4,"accession":"OP555633","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OP555633/2022-09-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1.3"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0562/2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168066T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG153":["D385-"],"OPG193":["Q245*"]},"labels":{"aa":"OPG153: D385-; OPG193: Q245*"}}},{"name":"OQ451897","node_attrs":{"div":7,"accession":"OQ451897","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ451897/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2022/RKI712"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","C54828T","C62205T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G178111A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A190660G"],"OPG016":["K84R"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG073":["R105K"],"OPG081":["M27I"]},"labels":{"aa":"OPG016: K84R; OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG073: R105K; OPG081: M27I"}}},{"name":"OR035732","node_attrs":{"div":4,"accession":"OR035732","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035732/2022-10-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-03"},"lineage":{"value":"B.1.3"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_126"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G92135A","T133102-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OR035715","node_attrs":{"div":3,"accession":"OR035715","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"strain_display":{"value":"Belgium/OR035715/2022-10-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"date":{"value":"2022-10-28"},"lineage":{"value":"B.1.3"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/UZ_REGA_109"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","T196712-","A196713-","T196714-"]}}},{"name":"OR264391","node_attrs":{"div":3,"accession":"OR264391","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"strain_display":{"value":"Australia/OR264391/2022-08-10"},"host":{"value":"Homo sapiens"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"date":{"value":"2022-08-10"},"lineage":{"value":"B.1.3"},"country":{"value":"Australia"},"strain":{"value":"2_A"},"region":{"value":"Oceania"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T80846-","T80847-","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OR134560","node_attrs":{"div":14,"accession":"OR134560","author":{"author":"Miller,H.,Bajwa,M.","value":"Miller,H.,Bajwa,M."},"strain_display":{"value":"USA/OR134560/2023-03-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"Delaware Public Health Lab, Sequencing/Bioinformatics"},"date":{"value":"2023-03-13"},"lineage":{"value":"B.1.3"},"country":{"value":"USA"},"strain":{"value":"B1221136"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C19558T","G32277A","C35688T","G39140A","G55059A","G75512A","C110402T","C121161T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C170673T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C179542T","C189174T"],"OPG034":["E150K"],"OPG049":["S292L"],"OPG073":["S28L"],"OPG095":["R237K"],"OPG139":["A70T"]},"labels":{"aa":"OPG034: E150K; OPG049: S292L; OPG073: S28L; OPG095: R237K; OPG139: A70T"}}},{"name":"OX248696","node_attrs":{"div":5,"accession":"OX248696","strain_display":{"value":"Slovakia/OX248696/2022-07-04"},"host":{"value":"Homo sapiens"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"date":{"value":"2022-07-04"},"lineage":{"value":"B.1.3"},"country":{"value":"Slovakia"},"strain":{"value":"RNA"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G37250A","C138080T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A196614-"],"OPG155":["E138K"]},"labels":{"aa":"OPG155: E138K"}}},{"name":"ON754986","node_attrs":{"div":3,"accession":"ON754986","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/ON754986/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"Slovenia"},"strain":{"value":"MPXV_SI2022_S5"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A161-","-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"ON754985","node_attrs":{"div":3,"accession":"ON754985","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/ON754985/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"Slovenia"},"strain":{"value":"MPXV_SI2022_S4"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A33-","T157-","-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"ON754984","node_attrs":{"div":3,"accession":"ON754984","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/ON754984/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"Slovenia"},"strain":{"value":"MPXV_SI2022_S3"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A240-","-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OP605551","node_attrs":{"div":3,"accession":"OP605551","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605551/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-08-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A33-","T157-","-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OP605552","node_attrs":{"div":3,"accession":"OP605552","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605552/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-09-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T38-","T157-","-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"ON838178","node_attrs":{"div":3,"accession":"ON838178","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/ON838178/2022-06-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-06-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"Slovenia"},"strain":{"value":"SI2022_S7"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A33-","T157-","-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"]}}},{"name":"OP314961","node_attrs":{"div":3,"accession":"OP314961","author":{"author":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R.","value":"Tegomoh,B.,Cross,S.T.,Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,Pratt,C.B.,Warden,D.E.,Iwen,P.C.,Donahue,M.,Wiley,M.R."},"strain_display":{"value":"USA/OP314961/2022-08-11"},"host":{"value":"Homo sapiens"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"date":{"value":"2022-08-11"},"lineage":{"value":"B.1.3"},"country":{"value":"USA"},"strain":{"value":"MPXV22/human/USA-NE-152"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A","-196616A","-196617A"]}}},{"name":"NODE_0000287","node_attrs":{"div":4,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A140126-","C140127-","T168120C","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-"],"OPG159":["N120-"],"OPG193":["F263L"]},"labels":{"aa":"OPG159: N120-; OPG193: F263L"}},"children":[{"name":"OP144214","node_attrs":{"div":5,"accession":"OP144214","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P."},"strain_display":{"value":"Belgium/OP144214/2022-06-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-06-16"},"lineage":{"value":"B.1.3"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/ITM_pt_25/Belgium/16-Jun-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C133161T","C157632T","C179235-"]}}},{"name":"ON950045","node_attrs":{"div":4,"accession":"ON950045","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,Van den Bossche,D.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Van Esbroeck,M.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,Van den Bossche,D.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Van Esbroeck,M."},"strain_display":{"value":"Belgium/ON950045/2022-05-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"date":{"value":"2022-05-27"},"lineage":{"value":"B.1.3"},"country":{"value":"Belgium"},"strain":{"value":"MPXV/ITM_pt_31/Belgium/27-May-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133102-","A140104-","A140105-","T140106-","A140107-","A140108-","C140109-","A140110-","A140111-","T140112-","T140113-","A140114-","T140115-","A140116-","A140117-","C140118-","A140119-","A140120-","T140121-","T140122-","A140123-","T140124-","A140125-","A140128-","A140129-","T140130-","T140131-","A140132-","T140133-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","A140143-","A140144-","T140145-","T140146-","G140147-","T140148-","T140149-","A140150-","T140151-","A140152-","A140153-","T140154-","A140155-","A140156-","T140157-","T140158-","A140159-","T140160-","A140161-","A140162-","T140163-","T140164-","G140165-","T140166-","T140167-","T179267-","-196615A"],"OPG159":["N113-","N114-","N115-","Y116-","N117-","N118-","Y119-","N121-","Y122-","N123-","N124-","Y125-","N126-","C127-","Y128-","N129-","N130-","Y131-","N132-","C133-","Y134-"]},"labels":{"aa":"OPG159: N113-, N114-, N115-, Y116-, N117-, N118-, Y119-, N121-, Y122-, N123-, N124-, Y125-, N126-, C127-, Y128-, N129-, N130-, Y131-, N132-, C133-, Y134-"}}}]},{"name":"NODE_0000288","node_attrs":{"div":4,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A33-","T157-","-607T","G167517A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG193":["E62K"]},"labels":{"aa":"OPG193: E62K"}},"children":[{"name":"ON754987","node_attrs":{"div":4,"accession":"ON754987","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/ON754987/2022-05-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-05-23"},"lineage":{"value":"B.1.3"},"country":{"value":"Slovenia"},"strain":{"value":"MPXV_SI2022_S1_VEROE6"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"ON609725","node_attrs":{"div":4,"accession":"ON609725","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Skubic,C.,Rozman,D.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Skubic,C.,Rozman,D.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/ON609725/2022-05-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia"},"date":{"value":"2022-05-23"},"lineage":{"value":"B.1.3"},"country":{"value":"Slovenia"},"strain":{"value":"SLO"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000289","node_attrs":{"div":4,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G85581A"],"OPG107":["V24I"]},"labels":{"aa":"OPG107: V24I"}},"children":[{"name":"OQ706779","node_attrs":{"div":5,"accession":"OQ706779","author":{"author":"Voegtly,L.J.,Paskey,A.C.,Rice,G.K.,Chitty,J.A.,Sugiharto,V.,Chen,H.-W.,Cer,R.Z.,Malagon,F.,Bishop-Lilly,K.A.","value":"Voegtly,L.J.,Paskey,A.C.,Rice,G.K.,Chitty,J.A.,Sugiharto,V.,Chen,H.-W.,Cer,R.Z.,Malagon,F.,Bishop-Lilly,K.A."},"strain_display":{"value":"USA/OQ706779/2022-08-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"Naval Medical Research Center Biological Defense Research Directorate, Bioinformatics and Genomics Department"},"date":{"value":"2022-08-25"},"lineage":{"value":"B.1.3"},"country":{"value":"USA"},"strain":{"value":"MD_NIDDL_54826"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","T160353C","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"]}}},{"name":"OR759179","node_attrs":{"div":5,"accession":"OR759179","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"strain_display":{"value":"Canada/OR759179/2022-09-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"date":{"value":"2022-09-01"},"lineage":{"value":"B.1.3"},"country":{"value":"Canada"},"strain":{"value":"hMpxV/Canada/ON-PHOL091/2022"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C122502T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG143":["D272N"]},"labels":{"aa":"OPG143: D272N"}}}]},{"name":"NODE_0000290","node_attrs":{"div":4,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G152776A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG180":["D29N"]},"labels":{"aa":"OPG180: D29N"}},"children":[{"name":"OQ581854","node_attrs":{"div":6,"accession":"OQ581854","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"strain_display":{"value":"Taiwan/OQ581854/2023-02-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"date":{"value":"2023-02-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"Taiwan"},"strain":{"value":"MPXV/human/Taiwan/109-005210/2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T64426C","G158406A","A192404-","G192405-","T192406-","A192411-"]}}},{"name":"NODE_0000291","node_attrs":{"div":15,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C15969T","C17998T","G40610A","C43803T","C63879T","G70190A","G118289A","C147011T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C159532T","G161629A","C189427T"],"OPG005":["P77S"],"OPG027":["E137K"],"OPG031":["M277I"],"OPG064":["G699E"],"OPG083":["D280N"],"OPG089":["E109K"],"OPG185":["P206S"],"OPG188":["E12K"]},"labels":{"aa":"OPG005: P77S; OPG027: E137K; OPG031: M277I; OPG064: G699E; OPG083: D280N; OPG089: E109K; OPG185: P206S; OPG188: E12K"}},"children":[{"name":"OQ451904","node_attrs":{"div":15,"accession":"OQ451904","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ451904/2023-01-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2023-01-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2023/RKI719"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OQ451903","node_attrs":{"div":15,"accession":"OQ451903","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OQ451903/2023-01-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2023-01-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2023/RKI718"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000292","node_attrs":{"div":6,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C8612T","C56018T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G187156A"],"OPG074":["E370K"]},"labels":{"aa":"OPG074: E370K"}},"children":[{"name":"OP605570","node_attrs":{"div":6,"accession":"OP605570","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605570/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-28-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000293","node_attrs":{"div":7,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G52232A"],"OPG071":["S736L"]},"labels":{"aa":"OPG071: S736L"}},"children":[{"name":"OP605585","node_attrs":{"div":7,"accession":"OP605585","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605585/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-44-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OP605581","node_attrs":{"div":7,"accession":"OP605581","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605581/2022-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-08-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-40-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A204-"]}}},{"name":"OP605578","node_attrs":{"div":10,"accession":"OP605578","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"strain_display":{"value":"Slovenia/OP605578/2022-07-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"date":{"value":"2022-07-XX"},"lineage":{"value":"B.1.3"},"country":{"value":"Slovenia"},"strain":{"value":"Slovenia-MPXV-36-2022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T163-","C64583A","C115217T","C183631T"],"OPG083":["G45V"],"OPG210":["S759F"]},"labels":{"aa":"OPG083: G45V; OPG210: S759F"}}}]}]},{"name":"NODE_0000300","node_attrs":{"div":4,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G105923A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG124":["L16F"]},"labels":{"aa":"OPG124: L16F","clade":"C.1"}},"children":[{"name":"LC753969","node_attrs":{"div":4,"accession":"LC753969","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"strain_display":{"value":"Japan/LC753969/2022-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"date":{"value":"2022-10-XX"},"lineage":{"value":"C.1"},"country":{"value":"Japan"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220176"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OQ721952","node_attrs":{"div":12,"accession":"OQ721952","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"strain_display":{"value":"Taiwan/OQ721952/2023-03-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"date":{"value":"2023-03-XX"},"lineage":{"value":"C.1"},"country":{"value":"Taiwan"},"strain":{"value":"MPXV/human/Taiwan/240031000030/2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C798T","C13503T","G33539A","G34948A","G40174A","G156025A","C166940T","A183935G","A184219G","G193223A"],"OPG025":["A589T"],"OPG054":["A350V"],"OPG057":["P8S"],"OPG210":["I860M","Y955C"]},"labels":{"aa":"OPG025: A589T; OPG054: A350V; OPG057: P8S; OPG210: I860M, Y955C"}}},{"name":"OQ581853","node_attrs":{"div":6,"accession":"OQ581853","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"strain_display":{"value":"Taiwan/OQ581853/2023-02-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"date":{"value":"2023-02-XX"},"lineage":{"value":"C.1"},"country":{"value":"Taiwan"},"strain":{"value":"MPXV/human/Taiwan/110-093831/2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T132513C","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C185069T"]}}},{"name":"LC753970","node_attrs":{"div":4,"accession":"LC753970","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"strain_display":{"value":"Japan/LC753970/2022-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"date":{"value":"2022-10-XX"},"lineage":{"value":"C.1"},"country":{"value":"Japan"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220187"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"LC753968","node_attrs":{"div":4,"accession":"LC753968","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"strain_display":{"value":"Japan/LC753968/2022-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"date":{"value":"2022-09-XX"},"lineage":{"value":"C.1"},"country":{"value":"Japan"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220165"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000302","node_attrs":{"div":5,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C3987T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T"]}},"children":[{"name":"OQ721954","node_attrs":{"div":10,"accession":"OQ721954","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"strain_display":{"value":"Taiwan/OQ721954/2023-03-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"date":{"value":"2023-03-XX"},"lineage":{"value":"C.1"},"country":{"value":"Taiwan"},"strain":{"value":"MPXV/human/Taiwan/110-539498/2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C798T","C11923T","T14737C","C48442T","G90825A","G102694A","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A191312G","G196412A"],"OPG015_dup":["I87V"],"OPG068":["A81V"]},"labels":{"aa":"OPG015_dup: I87V; OPG068: A81V"}}},{"name":"OQ581855","node_attrs":{"div":8,"accession":"OQ581855","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"strain_display":{"value":"Taiwan/OQ581855/2023-03-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"date":{"value":"2023-03-XX"},"lineage":{"value":"C.1"},"country":{"value":"Taiwan"},"strain":{"value":"MPXV/human/Taiwan/0310000009/2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G15797A","C41168T","A137251T","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-"]}}},{"name":"OR459803","node_attrs":{"div":12,"accession":"OR459803","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain_display":{"value":"South Korea/OR459803/2023-04-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2023-04-25"},"lineage":{"value":"C.1"},"country":{"value":"South Korea"},"strain":{"value":"MPXV-ROK-P033-2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","A17469C","A17484T","A17485T","A19360-","T20349A","C20608A","T114561G","G124742A","A125252-","C133103T","A148351-","-179172C","-179173A","-179174T","-179175T","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G193223A","-196615A","-196616A","-196617A"],"OPG030":["F117N","V122G"],"OPG035":["Y19F"],"OPG036":["V153F"],"OPG133":["N379T"],"OPG145":["D266N","I436-"]},"labels":{"aa":"OPG030: F117N, V122G; OPG035: Y19F; OPG036: V153F; OPG133: N379T; OPG145: D266N, I436-"}}},{"name":"NODE_0000303","node_attrs":{"div":6,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C166940T","-179172C","-179173A","-179174T","-179175T","G193223A"]}},"children":[{"name":"LC760461","node_attrs":{"div":7,"accession":"LC760461","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A."},"strain_display":{"value":"Japan/LC760461/2023-02-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"date":{"value":"2023-02-13"},"lineage":{"value":"C.1"},"country":{"value":"Japan"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220343"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C798T","C68765T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","G196412A"],"OPG086":["M33I"]},"labels":{"aa":"OPG086: M33I"}}},{"name":"LC760460","node_attrs":{"div":8,"accession":"LC760460","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A."},"strain_display":{"value":"Japan/LC760460/2023-01-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"date":{"value":"2023-01-23"},"lineage":{"value":"C.1"},"country":{"value":"Japan"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220304"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G48887A","G75699A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-"],"OPG096":["R38Q"]},"labels":{"aa":"OPG096: R38Q"}}},{"name":"LC756925","node_attrs":{"div":7,"accession":"LC756925","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"strain_display":{"value":"Japan/LC756925/2023-02-09"},"host":{"value":"Homo sapiens"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"date":{"value":"2023-02-09"},"lineage":{"value":"C.1"},"country":{"value":"Japan"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220342"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C84734T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-"]}}},{"name":"LC756924","node_attrs":{"div":7,"accession":"LC756924","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"strain_display":{"value":"Japan/LC756924/2023-01-30"},"host":{"value":"Homo sapiens"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"date":{"value":"2023-01-30"},"lineage":{"value":"C.1"},"country":{"value":"Japan"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220325"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C151434T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-"]}}},{"name":"LC756922","node_attrs":{"div":6,"accession":"LC756922","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"strain_display":{"value":"Japan/LC756922/2023-01-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"date":{"value":"2023-01-25"},"lineage":{"value":"C.1"},"country":{"value":"Japan"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220310"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-"]}}},{"name":"OR459782","node_attrs":{"div":8,"accession":"OR459782","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain_display":{"value":"South Korea/OR459782/2023-04-12"},"host":{"value":"Homo sapiens"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2023-04-12"},"lineage":{"value":"C.1"},"country":{"value":"South Korea"},"strain":{"value":"MPXV-ROK-P009-2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G12908A","C159231T","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR665166","node_attrs":{"div":11,"accession":"OR665166","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"strain_display":{"value":"USA/OR665166/2023-09-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"UW Virology, Laboratory Medicine"},"date":{"value":"2023-09-XX"},"lineage":{"value":"C.1"},"country":{"value":"USA"},"strain":{"value":"MpxV/human/USA/WA-UW-092809/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G13434A","G29650A","C33332T","G37974A","C74691T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179181C","-179226C","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG025":["R612C"],"OPG046":["T27I"],"OPG050":["R26Q"],"OPG056":["S354L"]},"labels":{"aa":"OPG025: R612C; OPG046: T27I; OPG050: R26Q; OPG056: S354L"}}},{"name":"OR459804","node_attrs":{"div":7,"accession":"OR459804","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain_display":{"value":"South Korea/OR459804/2023-04-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2023-04-25"},"lineage":{"value":"C.1"},"country":{"value":"South Korea"},"strain":{"value":"MPXV-ROK-P034-2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G163603A","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG189":["D91N"]},"labels":{"aa":"OPG189: D91N"}}},{"name":"OR459798","node_attrs":{"div":7,"accession":"OR459798","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain_display":{"value":"South Korea/OR459798/2023-04-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2023-04-22"},"lineage":{"value":"C.1"},"country":{"value":"South Korea"},"strain":{"value":"MPXV-ROK-P027-2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G5173A","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C192037T"]}}},{"name":"OR459797","node_attrs":{"div":6,"accession":"OR459797","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain_display":{"value":"South Korea/OR459797/2023-04-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2023-04-22"},"lineage":{"value":"C.1"},"country":{"value":"South Korea"},"strain":{"value":"MPXV-ROK-P026-2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A113921-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","T169716C","G169717A","T169721A","G169775A","T169776C","A169780T","-179181T","-179226T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG197":["M16T","S18T","V36T","E37D"]},"labels":{"aa":"OPG197: M16T, S18T, V36T, E37D"}}},{"name":"OR459796","node_attrs":{"div":8,"accession":"OR459796","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain_display":{"value":"South Korea/OR459796/2023-04-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2023-04-21"},"lineage":{"value":"C.1"},"country":{"value":"South Korea"},"strain":{"value":"MPXV-ROK-P024-2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G57129A","G144095A","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG165":["D194N"]},"labels":{"aa":"OPG165: D194N"}}},{"name":"OR459789","node_attrs":{"div":7,"accession":"OR459789","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain_display":{"value":"South Korea/OR459789/2023-04-18"},"host":{"value":"Homo sapiens"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2023-04-18"},"lineage":{"value":"C.1"},"country":{"value":"South Korea"},"strain":{"value":"MPXV-ROK-P016-2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C155209T","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"]}}},{"name":"OR459788","node_attrs":{"div":9,"accession":"OR459788","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain_display":{"value":"South Korea/OR459788/2023-04-18"},"host":{"value":"Homo sapiens"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2023-04-18"},"lineage":{"value":"C.1"},"country":{"value":"South Korea"},"strain":{"value":"MPXV-ROK-P015-2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C34542T","G85874A","C162233T","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG053":["R50Q"],"OPG188":["S213L"]},"labels":{"aa":"OPG053: R50Q; OPG188: S213L"}}},{"name":"OR459787","node_attrs":{"div":11,"accession":"OR459787","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain_display":{"value":"South Korea/OR459787/2023-04-17"},"host":{"value":"Homo sapiens"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2023-04-17"},"lineage":{"value":"C.1"},"country":{"value":"South Korea"},"strain":{"value":"MPXV-ROK-P014-2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A615-","C616-","T617-","G39380A","C69067-","A113921-","T124751-","C139775T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G152650A","T167061C","T170758-","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G187507A","A190959-","T196627-","C196628-","T196629-"],"OPG087":["H71-"],"OPG145":["F269-"],"OPG159":["S3F"],"OPG192":["C111R"],"OPG198":["F241-"]},"labels":{"aa":"OPG087: H71-; OPG145: F269-; OPG159: S3F; OPG192: C111R; OPG198: F241-"}}},{"name":"LC756923","node_attrs":{"div":6,"accession":"LC756923","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"strain_display":{"value":"Japan/LC756923/2023-01-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"date":{"value":"2023-01-25"},"lineage":{"value":"C.1"},"country":{"value":"Japan"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220318"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-"]}}},{"name":"OR459779","node_attrs":{"div":6,"accession":"OR459779","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain_display":{"value":"South Korea/OR459779/2023-04-06"},"host":{"value":"Homo sapiens"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2023-04-06"},"lineage":{"value":"C.1"},"country":{"value":"South Korea"},"strain":{"value":"MPXV-ROK-P006-2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000305","node_attrs":{"div":7,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C52108T","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OR459802","node_attrs":{"div":7,"accession":"OR459802","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain_display":{"value":"South Korea/OR459802/2023-04-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2023-04-25"},"lineage":{"value":"C.1"},"country":{"value":"South Korea"},"strain":{"value":"MPXV-ROK-P032-2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR459800","node_attrs":{"div":7,"accession":"OR459800","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain_display":{"value":"South Korea/OR459800/2023-04-23"},"host":{"value":"Homo sapiens"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2023-04-23"},"lineage":{"value":"C.1"},"country":{"value":"South Korea"},"strain":{"value":"MPXV-ROK-P029-2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR459794","node_attrs":{"div":8,"accession":"OR459794","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain_display":{"value":"South Korea/OR459794/2023-04-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2023-04-21"},"lineage":{"value":"C.1"},"country":{"value":"South Korea"},"strain":{"value":"MPXV-ROK-P021-2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T178915C"]}}},{"name":"OR459790","node_attrs":{"div":8,"accession":"OR459790","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain_display":{"value":"South Korea/OR459790/2023-04-18"},"host":{"value":"Homo sapiens"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2023-04-18"},"lineage":{"value":"C.1"},"country":{"value":"South Korea"},"strain":{"value":"MPXV-ROK-P017-2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T98717G","T124751-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","T169721A","T170758-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"],"OPG118":["L91W"],"OPG145":["F269-"],"OPG197":["S18T"],"OPG198":["F241-"]},"labels":{"aa":"OPG118: L91W; OPG145: F269-; OPG197: S18T; OPG198: F241-"}}}]},{"name":"NODE_0000306","node_attrs":{"div":8,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C149963T","G184562A"],"OPG176":["S52L"]},"labels":{"aa":"OPG176: S52L"}},"children":[{"name":"OR459778","node_attrs":{"div":9,"accession":"OR459778","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"strain_display":{"value":"South Korea/OR459778/2023-03-13"},"host":{"value":"Homo sapiens"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"date":{"value":"2023-03-13"},"lineage":{"value":"C.1"},"country":{"value":"South Korea"},"strain":{"value":"MPXV-ROK-P005-2023"},"region":{"value":"Asia"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G85691A","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000307","node_attrs":{"div":11,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C21062T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","G188348A","C188946T"],"OPG036":["M1I"]},"labels":{"aa":"OPG036: M1I"}},"children":[{"name":"OR643705","node_attrs":{"div":17,"accession":"OR643705","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"strain_display":{"value":"USA/OR643705/2023-08-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"date":{"value":"2023-08-16"},"lineage":{"value":"C.1"},"country":{"value":"USA"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00563/2023"},"region":{"value":"North America"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G21880A","G47532A","C125074T","G133704A","G133838A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T180483A"],"OPG037":["S185F"]},"labels":{"aa":"OPG037: S185F"}}},{"name":"NODE_0000308","node_attrs":{"div":13,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G101241A","G152866A","C191053-","A191054-","T191055-","G191056-","G191057-","A191058-","G191059-","T191060-","C191061-","G191062-","G191063-","T191064-","A191065-","G191066-","A191067-","T191068-","T191069-","T191070-","C191071-","A191072-","T191073-","G191074-","G191075-","C191076-","T191077-","G191078-","T191079-","C191080-","G191081-","A191082-","T191083-","G191084-","A191085-","G191086-","C191087-","A191088-","G191089-","T191090-","T191091-","T191092-","C191093-","A191094-","C191095-","G191096-","A191097-","C191098-","G191099-","A191100-","C191101-","C191102-","T191103-","C191104-","G191105-","A191106-","T191107-","C191108-","T191109-","T191110-","T191111-","G191112-","G191113-","T191114-","C191115-","A191116-","T191117-","T191118-","A191119-","T191120-","C191121-","T191122-","T191123-","T191124-","G191125-","G191126-","T191127-","A191128-","G191129-"],"OPG180":["D59N"]},"labels":{"aa":"OPG180: D59N"}},"children":[{"name":"OR381841","node_attrs":{"div":13,"accession":"OR381841","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR381841/2023-07-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-07-07"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0645/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR381833","node_attrs":{"div":14,"accession":"OR381833","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR381833/2023-07-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-07-03"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0634/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C176877T","-179186T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-"],"OPG205":["H408Y"]},"labels":{"aa":"OPG205: H408Y"}}},{"name":"OR326994","node_attrs":{"div":13,"accession":"OR326994","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR326994/2023-06-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-06-22"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0630/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-608T","G610-","T611-","-179186T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-"]}}},{"name":"OR326996","node_attrs":{"div":13,"accession":"OR326996","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR326996/2023-06-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-06-25"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0632/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T591A","-607T","-608T","-609T","A196619T"]}}},{"name":"OR326991","node_attrs":{"div":14,"accession":"OR326991","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR326991/2023-06-15"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-06-15"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0627/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G165862T"]}}},{"name":"OR326992","node_attrs":{"div":13,"accession":"OR326992","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR326992/2023-06-16"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-06-16"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0628/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179183T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-"]}}},{"name":"OR487990","node_attrs":{"div":13,"accession":"OR487990","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487990/2023-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-08-01"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0669/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR487991","node_attrs":{"div":14,"accession":"OR487991","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487991/2023-08-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-08-02"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0671/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C165219T"],"OPG190":["S33F"]},"labels":{"aa":"OPG190: S33F"}}},{"name":"OR487986","node_attrs":{"div":14,"accession":"OR487986","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487986/2023-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-08-01"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0665/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C72039T"]}}},{"name":"NODE_0000309","node_attrs":{"div":14,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A176268G"],"OPG205":["S205G"]},"labels":{"aa":"OPG205: S205G"}},"children":[{"name":"OR487999","node_attrs":{"div":14,"accession":"OR487999","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487999/2023-08-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-08-08"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0681/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR487998","node_attrs":{"div":14,"accession":"OR487998","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487998/2023-08-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-08-08"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0680/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000310","node_attrs":{"div":14,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C142797T"],"OPG164":["S7L"]},"labels":{"aa":"OPG164: S7L"}},"children":[{"name":"OR519724","node_attrs":{"div":14,"accession":"OR519724","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR519724/2023-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2023-08-XX"},"lineage":{"value":"C.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1022"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"]}}},{"name":"OR487989","node_attrs":{"div":15,"accession":"OR487989","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487989/2023-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-08-01"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0668/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G90093A"]}}},{"name":"NODE_0000311","node_attrs":{"div":16,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T57476C","G173397A"],"OPG075":["Q8R"]},"labels":{"aa":"OPG075: Q8R"}},"children":[{"name":"OR743500","node_attrs":{"div":16,"accession":"OR743500","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR743500/2023-10-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2023-10-XX"},"lineage":{"value":"C.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1031"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-"]}}},{"name":"OR487995","node_attrs":{"div":17,"accession":"OR487995","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487995/2023-08-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-08-03"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0675/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C175864T"],"OPG205":["S70L"]},"labels":{"aa":"OPG205: S70L"}}},{"name":"OR487992","node_attrs":{"div":16,"accession":"OR487992","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487992/2023-08-02"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-08-02"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0672/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000312","node_attrs":{"div":14,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G13563A"],"OPG025":["P569S"]},"labels":{"aa":"OPG025: P569S"}},"children":[{"name":"OR381843","node_attrs":{"div":14,"accession":"OR381843","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR381843/2023-07-10"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-07-10"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0649/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR381840","node_attrs":{"div":15,"accession":"OR381840","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR381840/2023-07-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-07-07"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0644/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C117631T"],"OPG136":["D653N"]},"labels":{"aa":"OPG136: D653N"}}},{"name":"OR381837","node_attrs":{"div":16,"accession":"OR381837","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR381837/2023-06-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-06-27"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0640/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C29342T","C148438T","G150556A"],"OPG046":["E130K"],"OPG174":["E320K"]},"labels":{"aa":"OPG046: E130K; OPG174: E320K"}}},{"name":"OR381835","node_attrs":{"div":14,"accession":"OR381835","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR381835/2023-06-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-06-27"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0638/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR381834","node_attrs":{"div":15,"accession":"OR381834","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR381834/2023-06-29"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-06-29"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0636/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G55497A"]}}},{"name":"OR326993","node_attrs":{"div":14,"accession":"OR326993","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR326993/2023-06-20"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-06-20"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0629/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"]}}},{"name":"OR488000","node_attrs":{"div":17,"accession":"OR488000","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR488000/2023-08-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-08-07"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0682/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G49821A","G87187A","C190352T"],"OPG068":["E541K"],"OPG109":["S754L"]},"labels":{"aa":"OPG068: E541K; OPG109: S754L"}}},{"name":"OR487982","node_attrs":{"div":14,"accession":"OR487982","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487982/2023-07-26"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-07-26"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0660/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T"]}}},{"name":"NODE_0000313","node_attrs":{"div":16,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C121394T","G162280A"],"OPG188":["E229K"]},"labels":{"aa":"OPG188: E229K"}},"children":[{"name":"OR487994","node_attrs":{"div":16,"accession":"OR487994","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487994/2023-08-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-08-03"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0674/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR487993","node_attrs":{"div":16,"accession":"OR487993","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487993/2023-08-03"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-08-03"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0673/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000314","node_attrs":{"div":15,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C37738T"],"OPG056":["E433K"]},"labels":{"aa":"OPG056: E433K"}},"children":[{"name":"OR487984","node_attrs":{"div":16,"accession":"OR487984","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487984/2023-07-28"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-07-28"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0663/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C15258T"],"OPG025":["D4N"]},"labels":{"aa":"OPG025: D4N"}}},{"name":"NODE_0000315","node_attrs":{"div":16,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G610-","T611-","G151847A"]}},"children":[{"name":"OR381844","node_attrs":{"div":18,"accession":"OR381844","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR381844/2023-07-18"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-07-18"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0650/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-609T","G138584A","G151875A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-"],"OPG156":["R276W"],"OPG178":["D123N"]},"labels":{"aa":"OPG156: R276W; OPG178: D123N"}}},{"name":"OR381842","node_attrs":{"div":16,"accession":"OR381842","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR381842/2023-07-07"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-07-07"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0646/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-609T"]}}},{"name":"OR381836","node_attrs":{"div":16,"accession":"OR381836","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR381836/2023-06-27"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-06-27"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0639/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR381838","node_attrs":{"div":17,"accession":"OR381838","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR381838/2023-07-04"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-07-04"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"Monkeypox/PT0641/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","-609T","C82619T"]}}},{"name":"OR326997","node_attrs":{"div":16,"accession":"OR326997","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR326997/2023-06-25"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-06-25"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0633/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-608T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-"]}}},{"name":"OR326995","node_attrs":{"div":17,"accession":"OR326995","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR326995/2023-06-22"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-06-22"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0631/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G695-","T696-","C34435T","A196625-","T196626-"],"OPG053":["A86T"]},"labels":{"aa":"OPG053: A86T"}}},{"name":"OR487997","node_attrs":{"div":16,"accession":"OR487997","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487997/2023-08-08"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-08-08"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0679/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"OR487985","node_attrs":{"div":21,"accession":"OR487985","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487985/2023-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-08-01"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0664/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C62243T","A132145G","G150054A","C162248T","G164445A"],"OPG081":["V15I"],"OPG176":["M82I"],"OPG188":["S218F"]},"labels":{"aa":"OPG081: V15I; OPG176: M82I; OPG188: S218F"}}},{"name":"OR487983","node_attrs":{"div":16,"accession":"OR487983","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487983/2023-07-26"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-07-26"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0661/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C780-","T781-","A196663-","A196664-"]}}},{"name":"OR487988","node_attrs":{"div":16,"accession":"OR487988","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487988/2023-08-01"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-08-01"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0667/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A784-","T785-","T196689-","C196690-"]}}},{"name":"OR487980","node_attrs":{"div":16,"accession":"OR487980","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487980/2023-07-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-07-21"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0656/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","-610G","-611T","A196614-"]}}},{"name":"OR487979","node_attrs":{"div":18,"accession":"OR487979","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487979/2023-07-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-07-21"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0655/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-610G","-611T","T12827C","C15258T"],"OPG023":["N25S"],"OPG025":["D4N"]},"labels":{"aa":"OPG023: N25S; OPG025: D4N"}}},{"name":"NODE_0000316","node_attrs":{"div":19,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-610G","-611T","C56879T","C57492T","G121291A","A196614-"],"OPG074":["E83K"],"OPG075":["E3K"]},"labels":{"aa":"OPG074: E83K; OPG075: E3K"}},"children":[{"name":"OR449307","node_attrs":{"div":21,"accession":"OR449307","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR449307/2023-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2023-08-XX"},"lineage":{"value":"C.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1021"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C84191T","C115068T","A179169-","T179170-","A179171-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG133":["R210K"]},"labels":{"aa":"OPG133: R210K"}}},{"name":"OR519723","node_attrs":{"div":20,"accession":"OR519723","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"strain_display":{"value":"Germany/OR519723/2023-08-XX"},"host":{"value":"Homo sapiens"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"date":{"value":"2023-08-XX"},"lineage":{"value":"C.1"},"country":{"value":"Germany"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G172945A"]}}},{"name":"OR487976","node_attrs":{"div":20,"accession":"OR487976","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487976/2023-07-19"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-07-19"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0652/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C181495T"],"OPG210":["S47L"]},"labels":{"aa":"OPG210: S47L"}}},{"name":"OR487978","node_attrs":{"div":21,"accession":"OR487978","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"strain_display":{"value":"Portugal/OR487978/2023-07-21"},"host":{"value":"Homo sapiens"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"date":{"value":"2023-07-21"},"lineage":{"value":"C.1"},"country":{"value":"Portugal"},"strain":{"value":"MPXV/PT0654/2023"},"region":{"value":"Europe"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","T12827C","T12833A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-"],"OPG023":["N25S"]},"labels":{"aa":"OPG023: N25S"}}}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}} \ No newline at end of file diff --git a/data_output/nextstrain/mpox/lineage-b.1/unreleased/CHANGELOG.md b/data_output/nextstrain/mpox/lineage-b.1/unreleased/CHANGELOG.md new file mode 100644 index 00000000..f941baec --- /dev/null +++ b/data_output/nextstrain/mpox/lineage-b.1/unreleased/CHANGELOG.md @@ -0,0 +1,13 @@ +## Unreleased + +Initial release of this dataset. This dataset is similar to the v2 dataset [`hMPXV_B.1/pseudo_ON563414`](https://github.com/nextstrain/nextclade_data/tree/2023-08-17--15-51-24--UTC/data/datasets/hMPXV_B.1/references/pseudo_ON563414/versions/2023-08-01T12%3A00%3A00Z/files) with some differences. + +### New and changed gene names + +Some genes have been renamed and one has been added. The new annotation is based on NCBI refseq annotations that were released in November 2022. The v2 dataset predates this refseq: + +- The 4 genes in the inverted terminal repeat segment (ITR) on both ends of the genome (OPG001, OPG002, OPG003,OPG015) are now all included. The genes on the 3' end (~positions 190000-197000) now have an `_dup` appended to distinguish them. +- The gene previously named `NBT03_gp052` is now called `OPG073` +- The gene previously named `NBT03_gp174` is now called `OPG016` +- The gene previously named `NBT03_gp175` is now called `OPG015_dup` +- Gene `OPG166` has been added diff --git a/data_output/nextstrain/mpox/lineage-b.1/unreleased/README.md b/data_output/nextstrain/mpox/lineage-b.1/unreleased/README.md new file mode 100644 index 00000000..2cb8b770 --- /dev/null +++ b/data_output/nextstrain/mpox/lineage-b.1/unreleased/README.md @@ -0,0 +1,24 @@ +# Nextclade dataset for "Mpox virus (Lineage B.1)" + +| Key | Value | +| ---------------------- | --------------------------------------------------------------------------------------------------------------------- | +| authors | [Cornelius Roemer](https://neherlab.org), [Richard Neher](https://neherlab.org), [Nextstrain](https://nextstrain.org) | +| data source | Genbank | +| workflow | [github.com/nextstrain/mpox/nextclade](https://github.com/nextstrain/mpox/nextclade) | +| nextclade dataset path | nextstrain/mpox/lineage-b.1 | +| annotation | [NC_063383.1](https://www.ncbi.nlm.nih.gov/nuccore/NC_063383) | +| clade definitions | [github.com/mpxv-lineages/lineage-designation](https://github.com/mpxv-lineages/lineage-designation) | +| related datasets | Mpox virus (All clades): `nextstrain/mpox/all-clades`
Mpox virus (Clade IIb) `nextstrain/mpox/clade-iib` | + +This dataset is for Mpox viruses of the 2022-2023 outbreak lineage B.1. Two broader datasets for clade IIb and all clades are available as well: `nextstrain/mpox/clade-iib` for Clade IIb and `nextstrain/mpox/all-clades` for all clades (I, IIa and IIb). + +The lineage system used is defined in [Happi et al. (2022)](https://doi.org/10.1371/journal.pbio.3001769). Lineage definitions are available at [github.com/mpxv-lineages/lineage-designation](https://github.com/nextstrain/mpox/nextclade). + +The reference used in this dataset is the clade IIb NCBI refseq `NC_063383.1` (Isolate `MPXV-M5312_HM12_Rivers`) with all B.1 defining SNPs added to make the mutation view less cluttered. + +The reference tree consists of around 1000 sequences with representatives from all B.1 sublineages. + + +## Further reading + +Read more about Nextclade datasets in Nextclade documentation: https://docs.nextstrain.org/projects/nextclade/en/stable/user/datasets.html diff --git a/data_output/nextstrain/mpox/lineage-b.1/unreleased/genome_annotation.gff3 b/data_output/nextstrain/mpox/lineage-b.1/unreleased/genome_annotation.gff3 new file mode 100644 index 00000000..432d5465 --- /dev/null +++ b/data_output/nextstrain/mpox/lineage-b.1/unreleased/genome_annotation.gff3 @@ -0,0 +1,391 @@ +##gff-version 3 +#!gff-spec-version 1.21 +#!processor NCBI annotwriter +##sequence-region NC_063383.1 1 197209 +##species https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10244 +NC_063383.1 RefSeq region 1 197209 . + . ID=NC_063383.1:1..197209;Dbxref=taxon:10244;collection-date=2018-08;country=Nigeria: Rivers State;gbkey=Src;genome=genomic;genotype=MPXV clade 2;isolate=MPXV-M5312_HM12_Rivers;mol_type=genomic DNA;nat-host=Homo sapiens +NC_063383.1 RefSeq long_terminal_repeat 1 6422 . - . ID=id-NC_063383.1:1..6422;gbkey=repeat_region;rpt_type=long_terminal_repeat +NC_063383.1 RefSeq gene 835 1575 . - . ID=gene-NBT03_gp001;Dbxref=GeneID:72551607;Name=OPG001;gbkey=Gene;gene=OPG001;gene_biotype=protein_coding;locus_tag=NBT03_gp001;old_locus_tag=MPXV-M5312_HM12_Rivers-001 +NC_063383.1 RefSeq CDS 835 1575 . - 0 ID=cds-YP_010377002.1;Parent=gene-NBT03_gp001;Dbxref=GenBank:YP_010377002.1,GeneID:72551607;Name=OPG001;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp001%3B Chemokine binding protein (Cop-C23L)%3B most abundant secreted protein%3B CC-chemokine binding%3B similar to VACV-WR J1L and VACV-Cop C23L;gbkey=CDS;gene=OPG001;locus_tag=NBT03_gp001;product=Chemokine binding protein;protein_id=YP_010377002.1 +NC_063383.1 RefSeq gene 1702 2751 . - . ID=gene-NBT03_gp002;Dbxref=GeneID:72551418;Name=OPG002;gbkey=Gene;gene=OPG002;gene_biotype=protein_coding;locus_tag=NBT03_gp002;old_locus_tag=MPXV-M5312_HM12_Rivers-002 +NC_063383.1 RefSeq CDS 1702 2751 . - 0 ID=cds-YP_010377003.1;Parent=gene-NBT03_gp002;Dbxref=GenBank:YP_010377003.1,GeneID:72551418;Name=OPG002;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: NBT03_gp002%3B TNF receptor (CrmB)%3B similar to VACV-WR J2L and VACV-Cop C22L;gbkey=CDS;gene=OPG002;locus_tag=NBT03_gp002;product=Crm-B secreted TNF-alpha-receptor-like protein;protein_id=YP_010377003.1 +NC_063383.1 RefSeq gene 2841 4607 . - . ID=gene-NBT03_gp003;Dbxref=GeneID:72551419;Name=OPG003;gbkey=Gene;gene=OPG003;gene_biotype=protein_coding;locus_tag=NBT03_gp003;old_locus_tag=MPXV-M5312_HM12_Rivers-003 +NC_063383.1 RefSeq CDS 2841 4607 . - 0 ID=cds-YP_010377004.1;Parent=gene-NBT03_gp003;Dbxref=GenBank:YP_010377004.1,GeneID:72551419;Name=OPG003;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp003%3B Ankyrin%3B similar to VACV-WR J3L and VACV-Cop C19L;gbkey=CDS;gene=OPG003;locus_tag=NBT03_gp003;product=Ankyrin repeat protein (25);protein_id=YP_010377004.1 +NC_063383.1 RefSeq gene 4843 6156 . - . ID=gene-NBT03_gp004;Dbxref=GeneID:72551420;Name=OPG015;gbkey=Gene;gene=OPG015;gene_biotype=protein_coding;locus_tag=NBT03_gp004;old_locus_tag=MPXV-M5312_HM12_Rivers-004 +NC_063383.1 RefSeq CDS 4843 6156 . - 0 ID=cds-YP_010377005.1;Parent=gene-NBT03_gp004;Dbxref=GenBank:YP_010377005.1,GeneID:72551420;Name=OPG015;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp004%3B Ankyrin%3B similar to VACV-WR D1L and CPXV-017;gbkey=CDS;gene=OPG015;locus_tag=NBT03_gp004;product=Ankyrin repeat protein (39);protein_id=YP_010377005.1 +NC_063383.1 RefSeq sequence_feature 6270 6419 . - . ID=id-NC_063383.1:6270..6419;exon_number=OPG016;gbkey=misc_feature;number=OPG016 +NC_063383.1 RefSeq sequence_feature 6444 6885 . - . ID=id-NC_063383.1:6444..6885;exon_number=OPG017;gbkey=misc_feature;number=OPG017 +NC_063383.1 RefSeq sequence_feature 6966 7463 . - . ID=id-NC_063383.1:6966..7463;exon_number=OPG018;gbkey=misc_feature;number=OPG018 +NC_063383.1 RefSeq gene 7580 8008 . + . ID=gene-NBT03_gp005;Dbxref=GeneID:72551421;Name=OPG019;gbkey=Gene;gene=OPG019;gene_biotype=protein_coding;locus_tag=NBT03_gp005;old_locus_tag=MPXV-M5312_HM12_Rivers-006 +NC_063383.1 RefSeq CDS 7580 8008 . + 0 ID=cds-YP_010377006.1;Parent=gene-NBT03_gp005;Dbxref=GenBank:YP_010377006.1,GeneID:72551421;Name=OPG019;Note=Taxonomic breadth: chordopoxvirinae%3B secreted growth factor Secreted EGF-like protein%3B similar to VACV-WR D3R and VACV-Cop C11R;gbkey=CDS;gene=OPG019;locus_tag=NBT03_gp005;product=EGF-like domain protein;protein_id=YP_010377006.1 +NC_063383.1 RefSeq sequence_feature 8136 9102 . - . ID=id-NC_063383.1:8136..9102;exon_number=OPG020;gbkey=misc_feature;number=OPG020 +NC_063383.1 RefSeq gene 9587 10315 . + . ID=gene-NBT03_gp006;Dbxref=GeneID:72551422;Name=OPG021;gbkey=Gene;gene=OPG021;gene_biotype=protein_coding;locus_tag=NBT03_gp006;old_locus_tag=MPXV-M5312_HM12_Rivers-008 +NC_063383.1 RefSeq CDS 9587 10315 . + 0 ID=cds-YP_010377007.1;Parent=gene-NBT03_gp006;Dbxref=GenBank:YP_010377007.1,GeneID:72551422;Name=OPG021;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp008%3B Zinc finger-like protein%3B zinc binding%3B virosome localization%3B virulence factor%3B inhibition of apoptosis induced by UV irradiation%3B similar to VACV-WR D5R;gbkey=CDS;gene=OPG021;locus_tag=NBT03_gp006;product=Zinc finger-like protein (2);protein_id=YP_010377007.1 +NC_063383.1 RefSeq gene 10478 10858 . - . ID=gene-NBT03_gp007;Dbxref=GeneID:72551423;Name=OPG022;gbkey=Gene;gene=OPG022;gene_biotype=protein_coding;locus_tag=NBT03_gp007;old_locus_tag=MPXV-M5312_HM12_Rivers-009 +NC_063383.1 RefSeq CDS 10478 10858 . - 0 ID=cds-YP_010377008.1;Parent=gene-NBT03_gp007;Dbxref=GenBank:YP_010377008.1,GeneID:72551423;Name=OPG022;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp009%3B secreted IL-18 binding protein%3B Soluble IL-18 binding protein (Bsh-D7L)%3B similar to VACV-WR D6L;gbkey=CDS;gene=OPG022;locus_tag=NBT03_gp007;product=Interleukin-18-binding protein;protein_id=YP_010377008.1 +NC_063383.1 RefSeq gene 10918 12900 . - . ID=gene-NBT03_gp008;Dbxref=GeneID:72551424;Name=OPG023;gbkey=Gene;gene=OPG023;gene_biotype=protein_coding;locus_tag=NBT03_gp008;old_locus_tag=MPXV-M5312_HM12_Rivers-010 +NC_063383.1 RefSeq CDS 10918 12900 . - 0 ID=cds-YP_010377009.1;Parent=gene-NBT03_gp008;Dbxref=GenBank:YP_010377009.1,GeneID:72551424;Name=OPG023;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp010%3B host range%3B ankyrin-like%3B Ankyrin/Host Range (Bang-D8L)%3B similar to VACV-WR D7L;gbkey=CDS;gene=OPG023;locus_tag=NBT03_gp008;product=Ankyrin repeat protein (2);protein_id=YP_010377009.1 +NC_063383.1 RefSeq gene 13034 13228 . - . ID=gene-NBT03_gp009;Dbxref=GeneID:72551425;Name=OPG024;gbkey=Gene;gene=OPG024;gene_biotype=protein_coding;locus_tag=NBT03_gp009;old_locus_tag=MPXV-M5312_HM12_Rivers-011 +NC_063383.1 RefSeq CDS 13034 13228 . - 0 ID=cds-YP_010377010.1;Parent=gene-NBT03_gp009;Dbxref=GenBank:YP_010377010.1,GeneID:72551425;Name=OPG024;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp011%3B ANK-containing protein%3B similar to VACV-WR D8L;gbkey=CDS;gene=OPG024;locus_tag=NBT03_gp009;product=retroviral pseudoprotease-like protein;protein_id=YP_010377010.1 +NC_063383.1 RefSeq gene 13375 15267 . - . ID=gene-NBT03_gp010;Dbxref=GeneID:72551426;Name=OPG025;gbkey=Gene;gene=OPG025;gene_biotype=protein_coding;locus_tag=NBT03_gp010;old_locus_tag=MPXV-M5312_HM12_Rivers-012 +NC_063383.1 RefSeq CDS 13375 15267 . - 0 ID=cds-YP_010377011.1;Parent=gene-NBT03_gp010;Dbxref=GenBank:YP_010377011.1,GeneID:72551426;Name=OPG025;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp012%3B ankyrin-like%3B Type I IFN resistance%3B similar to VACV-WR D9L and VACV-Cop C9L;gbkey=CDS;gene=OPG025;locus_tag=NBT03_gp010;product=Ankyrin repeat protein (14);protein_id=YP_010377011.1 +NC_063383.1 RefSeq sequence_feature 15310 15854 . - . ID=id-NC_063383.1:15310..15854;exon_number=OPG026;gbkey=misc_feature;number=OPG026 +NC_063383.1 RefSeq gene 15925 16377 . - . ID=gene-NBT03_gp011;Dbxref=GeneID:72551427;Name=OPG027;gbkey=Gene;gene=OPG027;gene_biotype=protein_coding;locus_tag=NBT03_gp011;old_locus_tag=MPXV-M5312_HM12_Rivers-013 +NC_063383.1 RefSeq CDS 15925 16377 . - 0 ID=cds-YP_010377012.1;Parent=gene-NBT03_gp011;Dbxref=GenBank:YP_010377012.1,GeneID:72551427;Name=OPG027;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp013%3B host range%3B Type 1 IFN inhibitor%3B similar to VACV-WR D10L and VACV-Cop C7L;gbkey=CDS;gene=OPG027;locus_tag=NBT03_gp011;product=Host range protein;protein_id=YP_010377012.1 +NC_063383.1 RefSeq gene 16602 17069 . - . ID=gene-NBT03_gp012;Dbxref=GeneID:72551428;Name=OPG029;gbkey=Gene;gene=OPG029;gene_biotype=protein_coding;locus_tag=NBT03_gp012;old_locus_tag=MPXV-M5312_HM12_Rivers-014 +NC_063383.1 RefSeq CDS 16602 17069 . - 0 ID=cds-YP_010377013.1;Parent=gene-NBT03_gp012;Dbxref=GenBank:YP_010377013.1,GeneID:72551428;Name=OPG029;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp014%3B Putative tlr signaling inhibitor%2C IFN-beta inhibitor%3B similar to VACV-WR D11L and VACV-Cop C6L;gbkey=CDS;gene=OPG029;locus_tag=NBT03_gp012;product=Bcl-2-like protein;protein_id=YP_010377013.1 +NC_063383.1 RefSeq gene 17213 17833 . - . ID=gene-NBT03_gp013;Dbxref=GeneID:72551429;Name=OPG030;gbkey=Gene;gene=OPG030;gene_biotype=protein_coding;locus_tag=NBT03_gp013;old_locus_tag=MPXV-M5312_HM12_Rivers-015 +NC_063383.1 RefSeq CDS 17213 17833 . - 0 ID=cds-YP_010377014.1;Parent=gene-NBT03_gp013;Dbxref=GenBank:YP_010377014.1,GeneID:72551429;Name=OPG030;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp015%3B BTB domain of kelch-like protein%3B Kelch-like protein%3B similar to VACV-WR D12L and VACV-Cop C5L;gbkey=CDS;gene=OPG030;locus_tag=NBT03_gp013;product=Kelch-like protein (1);protein_id=YP_010377014.1 +NC_063383.1 RefSeq gene 17878 18828 . - . ID=gene-NBT03_gp014;Dbxref=GeneID:72551430;Name=OPG031;gbkey=Gene;gene=OPG031;gene_biotype=protein_coding;locus_tag=NBT03_gp014;old_locus_tag=MPXV-M5312_HM12_Rivers-016 +NC_063383.1 RefSeq CDS 17878 18828 . - 0 ID=cds-YP_010377015.1;Parent=gene-NBT03_gp014;Dbxref=GenBank:YP_010377015.1,GeneID:72551430;Name=OPG031;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp016%3B IL-1 receptor antagonist%3B similar to VACV-WR D13L and VACV-Cop C10L;gbkey=CDS;gene=OPG031;locus_tag=NBT03_gp014;product=C4L/C10L-like family protein;protein_id=YP_010377015.1 +NC_063383.1 RefSeq sequence_feature 18902 19288 . - . ID=id-NC_063383.1:18902..19288;exon_number=OPG033;gbkey=misc_feature;number=OPG033 +NC_063383.1 RefSeq gene 19361 20005 . - . ID=gene-NBT03_gp015;Dbxref=GeneID:72551431;Name=OPG034;gbkey=Gene;gene=OPG034;gene_biotype=protein_coding;locus_tag=NBT03_gp015;old_locus_tag=MPXV-M5312_HM12_Rivers-018 +NC_063383.1 RefSeq CDS 19361 20005 . - 0 ID=cds-YP_010377017.1;Parent=gene-NBT03_gp015;Dbxref=GenBank:YP_010377017.1,GeneID:72551431;Name=OPG034;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp022%3B Putative TLR signalling inhibitor%3B start of ORF is missing approx. 18 AA compared to CPXVs%3B similar to VACV-WR D19L and VACV-Cop C1L;gbkey=CDS;gene=OPG034;locus_tag=NBT03_gp015;product=Bcl-2-like protein;protein_id=YP_010377017.1 +NC_063383.1 RefSeq gene 20051 20404 . - . ID=gene-NBT03_gp016;Dbxref=GeneID:72551432;Name=OPG035;gbkey=Gene;gene=OPG035;gene_biotype=protein_coding;locus_tag=NBT03_gp016;old_locus_tag=MPXV-M5312_HM12_Rivers-019 +NC_063383.1 RefSeq CDS 20051 20404 . - 0 ID=cds-YP_010377018.1;Parent=gene-NBT03_gp016;Dbxref=GenBank:YP_010377018.1,GeneID:72551432;Name=OPG035;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp023%3B secreted virulence factor%3B Putative tlr signaling inhibitor%3B Anti-apoptotic Bcl-2-like protein%3B similar to VACV-WR P1L and VACV-Cop N1L;gbkey=CDS;gene=OPG035;locus_tag=NBT03_gp016;product=Bcl-2-like protein;protein_id=YP_010377018.1 +NC_063383.1 RefSeq gene 20531 21064 . - . ID=gene-NBT03_gp017;Dbxref=GeneID:72551433;Name=OPG036;gbkey=Gene;gene=OPG036;gene_biotype=protein_coding;locus_tag=NBT03_gp017;old_locus_tag=MPXV-M5312_HM12_Rivers-020 +NC_063383.1 RefSeq CDS 20531 21064 . - 0 ID=cds-YP_010377019.1;Parent=gene-NBT03_gp017;Dbxref=GenBank:YP_010377019.1,GeneID:72551433;Name=OPG036;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp024%3B Alpha amanatin target protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR P2L and VACV-Cop #N2L;gbkey=CDS;gene=OPG036;locus_tag=NBT03_gp017;product=Bcl-2-like protein;protein_id=YP_010377019.1 +NC_063383.1 RefSeq gene 21105 22433 . - . ID=gene-NBT03_gp018;Dbxref=GeneID:72551434;Name=OPG037;gbkey=Gene;gene=OPG037;gene_biotype=protein_coding;locus_tag=NBT03_gp018;old_locus_tag=MPXV-M5312_HM12_Rivers-021 +NC_063383.1 RefSeq CDS 21105 22433 . - 0 ID=cds-YP_010377020.1;Parent=gene-NBT03_gp018;Dbxref=GenBank:YP_010377020.1,GeneID:72551434;Name=OPG037;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp025%3B ankyrin-like%3B ANK-containing protein%3B apoptosis inhibitor%3B start of ORF is missing approx. 31 AA compared to CPXVs%3B similar to VACV-WR O1L and VACV-Cop M1L;gbkey=CDS;gene=OPG037;locus_tag=NBT03_gp018;product=Ankyrin-like protein (1);protein_id=YP_010377020.1 +NC_063383.1 RefSeq gene 22497 23159 . - . ID=gene-NBT03_gp019;Dbxref=GeneID:72551435;Name=OPG038;gbkey=Gene;gene=OPG038;gene_biotype=protein_coding;locus_tag=NBT03_gp019;old_locus_tag=MPXV-M5312_HM12_Rivers-022 +NC_063383.1 RefSeq CDS 22497 23159 . - 0 ID=cds-YP_010377021.1;Parent=gene-NBT03_gp019;Dbxref=GenBank:YP_010377021.1,GeneID:72551435;Name=OPG038;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp026%3B NFkB inhibitor%3B similar to VACV-WR O2L and VACV-Cop M2L;gbkey=CDS;gene=OPG038;locus_tag=NBT03_gp019;product=NFkB inhibitor;protein_id=YP_010377021.1 +NC_063383.1 RefSeq gene 23264 24118 . - . ID=gene-NBT03_gp020;Dbxref=GeneID:72551436;Name=OPG039;gbkey=Gene;gene=OPG039;gene_biotype=protein_coding;locus_tag=NBT03_gp020;old_locus_tag=MPXV-M5312_HM12_Rivers-023 +NC_063383.1 RefSeq CDS 23264 24118 . - 0 ID=cds-YP_010377022.1;Parent=gene-NBT03_gp020;Dbxref=GenBank:YP_010377022.1,GeneID:72551436;Name=OPG039;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp027%3B host range%3B ankyrin-like%3B Ankyrin/NFkB inhibitor%3B similar to VACV-WR C1L and VACV-Cop K1L;gbkey=CDS;gene=OPG039;locus_tag=NBT03_gp020;product=Ankyrin-like protein (3);protein_id=YP_010377022.1 +NC_063383.1 RefSeq gene 24351 25478 . - . ID=gene-NBT03_gp021;Dbxref=GeneID:72551437;Name=OPG040;gbkey=Gene;gene=OPG040;gene_biotype=protein_coding;locus_tag=NBT03_gp021;old_locus_tag=MPXV-M5312_HM12_Rivers-024 +NC_063383.1 RefSeq CDS 24351 25478 . - 0 ID=cds-YP_010377023.1;Parent=gene-NBT03_gp021;Dbxref=GenBank:YP_010377023.1,GeneID:72551437;Name=OPG040;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp028%3B serine protease inhibitor-like%2C SPI-3%3B inhibition of the ability of infected cells to fuse%3B Serpin 1%2C2%2C3%3B similar to VACV-WR C2L and VACV-Cop K2L;gbkey=CDS;gene=OPG040;locus_tag=NBT03_gp021;product=Serpin;protein_id=YP_010377023.1 +NC_063383.1 RefSeq sequence_feature 25529 25767 . - . ID=id-NC_063383.1:25529..25767;exon_number=OPG041;gbkey=misc_feature;number=OPG041 +NC_063383.1 RefSeq gene 25823 27097 . - . ID=gene-NBT03_gp022;Dbxref=GeneID:72551438;Name=OPG042;gbkey=Gene;gene=OPG042;gene_biotype=protein_coding;locus_tag=NBT03_gp022;old_locus_tag=MPXV-M5312_HM12_Rivers-026 +NC_063383.1 RefSeq CDS 25823 27097 . - 0 ID=cds-YP_010377025.1;Parent=gene-NBT03_gp022;Dbxref=GenBank:YP_010377025.1,GeneID:72551438;Name=OPG042;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp030%3B phospholipase D-like%3B Phospholipase-D-like protein%3B similar to VACV-WR C4L and VACV-Cop K4L;gbkey=CDS;gene=OPG042;locus_tag=NBT03_gp022;product=Phospholipase-D-like protein;protein_id=YP_010377025.1 +NC_063383.1 RefSeq gene 27125 27955 . - . ID=gene-NBT03_gp023;Dbxref=GeneID:72551439;Name=OPG043;gbkey=Gene;gene=OPG043;gene_biotype=protein_coding;locus_tag=NBT03_gp023;old_locus_tag=MPXV-M5312_HM12_Rivers-027 +NC_063383.1 RefSeq CDS 27125 27955 . - 0 ID=cds-YP_010377026.1;Parent=gene-NBT03_gp023;Dbxref=GenBank:YP_010377026.1,GeneID:72551439;Name=OPG043;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp031%3B lysophospholipase-like%3B Monoglyceride lipase%3B similar to VACV-WR C5L and VACV-Cop K5L;gbkey=CDS;gene=OPG043;locus_tag=NBT03_gp023;product=Putative monoglyceride lipase;protein_id=YP_010377026.1 +NC_063383.1 RefSeq gene 28091 28540 . + . ID=gene-NBT03_gp024;Dbxref=GeneID:72551440;Name=OPG044;gbkey=Gene;gene=OPG044;gene_biotype=protein_coding;locus_tag=NBT03_gp024;old_locus_tag=MPXV-M5312_HM12_Rivers-028 +NC_063383.1 RefSeq CDS 28091 28540 . + 0 ID=cds-YP_010377027.1;Parent=gene-NBT03_gp024;Dbxref=GenBank:YP_010377027.1,GeneID:72551440;Name=OPG044;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp032%3B Putative tlr signaling inhibitor%3B Host immune response repressor%3B similar to VACV-WR C6R and VACV-Cop #K7R;gbkey=CDS;gene=OPG044;locus_tag=NBT03_gp024;product=Bcl-2-like protein;protein_id=YP_010377027.1 +NC_063383.1 RefSeq gene 28603 29262 . - . ID=gene-NBT03_gp025;Dbxref=GeneID:72551441;Name=OPG045;gbkey=Gene;gene=OPG045;gene_biotype=protein_coding;locus_tag=NBT03_gp025;old_locus_tag=MPXV-M5312_HM12_Rivers-029 +NC_063383.1 RefSeq CDS 28603 29262 . - 0 ID=cds-YP_010377028.1;Parent=gene-NBT03_gp025;Dbxref=GenBank:YP_010377028.1,GeneID:72551441;Name=OPG045;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp033%3B Caspase-9 (apoptosis) inhibitor (mitochondrial- associated)%3B similar to VACV-WR C7L and VACV-Cop F1L;gbkey=CDS;gene=OPG045;locus_tag=NBT03_gp025;product=Caspase-9 inhibitor;protein_id=YP_010377028.1 +NC_063383.1 RefSeq gene 29274 29729 . - . ID=gene-NBT03_gp026;Dbxref=GeneID:72551442;Name=OPG046;gbkey=Gene;gene=OPG046;gene_biotype=protein_coding;locus_tag=NBT03_gp026;old_locus_tag=MPXV-M5312_HM12_Rivers-030 +NC_063383.1 RefSeq CDS 29274 29729 . - 0 ID=cds-YP_010377029.1;Parent=gene-NBT03_gp026;Dbxref=GenBank:YP_010377029.1,GeneID:72551442;Name=OPG046;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp034%3B deoxyuridine triphosphatase%3B dUTPase%3B similar to VACV-WR C8L and VACV-Cop F2L;gbkey=CDS;gene=OPG046;locus_tag=NBT03_gp026;product=dUTPase;protein_id=YP_010377029.1 +NC_063383.1 RefSeq gene 29746 31194 . - . ID=gene-NBT03_gp027;Dbxref=GeneID:72551443;Name=OPG047;gbkey=Gene;gene=OPG047;gene_biotype=protein_coding;locus_tag=NBT03_gp027;old_locus_tag=MPXV-M5312_HM12_Rivers-031 +NC_063383.1 RefSeq CDS 29746 31194 . - 0 ID=cds-YP_010377030.1;Parent=gene-NBT03_gp027;Dbxref=GenBank:YP_010377030.1,GeneID:72551443;Name=OPG047;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp035%3B kelch-like%3B Kelch-like protein%3B similar to VACV-WR C9L and VACV-Cop F3L;gbkey=CDS;gene=OPG047;locus_tag=NBT03_gp027;product=Kelch-like protein (2);protein_id=YP_010377030.1 +NC_063383.1 RefSeq gene 31205 32164 . - . ID=gene-NBT03_gp028;Dbxref=GeneID:72551444;Name=OPG048;gbkey=Gene;gene=OPG048;gene_biotype=protein_coding;locus_tag=NBT03_gp028;old_locus_tag=MPXV-M5312_HM12_Rivers-032 +NC_063383.1 RefSeq CDS 31205 32164 . - 0 ID=cds-YP_010377031.1;Parent=gene-NBT03_gp028;Dbxref=GenBank:YP_010377031.1,GeneID:72551444;Name=OPG048;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp036%3B Ribonucleotide reductase small subunit%2C R2%3B similar to VACV-WR C10L and VACV-Cop F4L;gbkey=CDS;gene=OPG048;locus_tag=NBT03_gp028;product=Ribonucleotide reductase small subunit;protein_id=YP_010377031.1 +NC_063383.1 RefSeq gene 32195 33151 . - . ID=gene-NBT03_gp029;Dbxref=GeneID:72551445;Name=OPG049;gbkey=Gene;gene=OPG049;gene_biotype=protein_coding;locus_tag=NBT03_gp029;old_locus_tag=MPXV-M5312_HM12_Rivers-033 +NC_063383.1 RefSeq CDS 32195 33151 . - 0 ID=cds-YP_010377032.1;Parent=gene-NBT03_gp029;Dbxref=GenBank:YP_010377032.1,GeneID:72551445;Name=OPG049;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp037%3B 36kDa major membrane protein%3B similar to VACV-WR C11L and VACV-Cop F5L;gbkey=CDS;gene=OPG049;locus_tag=NBT03_gp029;product=Telomere-binding protein I6 (1);protein_id=YP_010377032.1 +NC_063383.1 RefSeq gene 33181 33408 . - . ID=gene-NBT03_gp030;Dbxref=GeneID:72551446;Name=OPG050;gbkey=Gene;gene=OPG050;gene_biotype=protein_coding;locus_tag=NBT03_gp030;old_locus_tag=MPXV-M5312_HM12_Rivers-034 +NC_063383.1 RefSeq CDS 33181 33408 . - 0 ID=cds-YP_010377033.1;Parent=gene-NBT03_gp030;Dbxref=GenBank:YP_010377033.1,GeneID:72551446;Name=OPG050;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp038%3B Hypothetical protein%3B similar to VACV-WR C12L and VACV-Cop F6L;gbkey=CDS;gene=OPG050;locus_tag=NBT03_gp030;product=CPXV053 protein;protein_id=YP_010377033.1 +NC_063383.1 RefSeq gene 33425 33649 . - . ID=gene-NBT03_gp031;Dbxref=GeneID:72551447;Name=OPG051;gbkey=Gene;gene=OPG051;gene_biotype=protein_coding;locus_tag=NBT03_gp031;old_locus_tag=MPXV-M5312_HM12_Rivers-035 +NC_063383.1 RefSeq CDS 33425 33649 . - 0 ID=cds-YP_010377034.1;Parent=gene-NBT03_gp031;Dbxref=GenBank:YP_010377034.1,GeneID:72551447;Name=OPG051;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp039%3B Hypothetical protein%3B similar to VACV-WR C13L and VACV-Cop F7L;gbkey=CDS;gene=OPG051;locus_tag=NBT03_gp031;product=CPXV054 protein;protein_id=YP_010377034.1 +NC_063383.1 RefSeq gene 33801 33995 . - . ID=gene-NBT03_gp032;Dbxref=GeneID:72551448;Name=OPG052;gbkey=Gene;gene=OPG052;gene_biotype=protein_coding;locus_tag=NBT03_gp032;old_locus_tag=MPXV-M5312_HM12_Rivers-036 +NC_063383.1 RefSeq CDS 33801 33995 . - 0 ID=cds-YP_010377035.1;Parent=gene-NBT03_gp032;Dbxref=GenBank:YP_010377035.1,GeneID:72551448;Name=OPG052;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp040%3B Cytoplasmic protein%3B similar to VACV-WR C14L and VACV-Cop F8L;gbkey=CDS;gene=OPG052;locus_tag=NBT03_gp032;product=Cytoplasmic protein;protein_id=YP_010377035.1 +NC_063383.1 RefSeq gene 34052 34690 . - . ID=gene-NBT03_gp033;Dbxref=GeneID:72551449;Name=OPG053;gbkey=Gene;gene=OPG053;gene_biotype=protein_coding;locus_tag=NBT03_gp033;old_locus_tag=MPXV-M5312_HM12_Rivers-037 +NC_063383.1 RefSeq CDS 34052 34690 . - 0 ID=cds-YP_010377036.1;Parent=gene-NBT03_gp033;Dbxref=GenBank:YP_010377036.1,GeneID:72551449;Name=OPG053;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp041%3B S-S bond formation pathway protein substrate%3B similar to VACV-WR C15L and VACV-Cop F9L;gbkey=CDS;gene=OPG053;locus_tag=NBT03_gp033;product=IMV membrane protein L1R;protein_id=YP_010377036.1 +NC_063383.1 RefSeq gene 34677 35996 . - . ID=gene-NBT03_gp034;Dbxref=GeneID:72551450;Name=OPG054;gbkey=Gene;gene=OPG054;gene_biotype=protein_coding;locus_tag=NBT03_gp034;old_locus_tag=MPXV-M5312_HM12_Rivers-038 +NC_063383.1 RefSeq CDS 34677 35996 . - 0 ID=cds-YP_010377037.1;Parent=gene-NBT03_gp034;Dbxref=GenBank:YP_010377037.1,GeneID:72551450;Name=OPG054;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp042%3B serine%3B Essential Ser/Thr kinase morph%3B similar to VACV-WR C16L and VACV-Cop F10L;gbkey=CDS;gene=OPG054;locus_tag=NBT03_gp034;product=Serine/threonine-protein kinase;protein_id=YP_010377037.1 +NC_063383.1 RefSeq gene 36019 37083 . - . ID=gene-NBT03_gp035;Dbxref=GeneID:72551451;Name=OPG055;gbkey=Gene;gene=OPG055;gene_biotype=protein_coding;locus_tag=NBT03_gp035;old_locus_tag=MPXV-M5312_HM12_Rivers-039 +NC_063383.1 RefSeq CDS 36019 37083 . - 0 ID=cds-YP_010377038.1;Parent=gene-NBT03_gp035;Dbxref=GenBank:YP_010377038.1,GeneID:72551451;Name=OPG055;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp043%3B RhoA signalling inhibitor%2C virus release protein%3B MC018%3B similar to VACV-WR C17L and VACV-Cop F11L;gbkey=CDS;gene=OPG055;locus_tag=NBT03_gp035;product=Protein F11;protein_id=YP_010377038.1 +NC_063383.1 RefSeq gene 37127 39034 . - . ID=gene-NBT03_gp036;Dbxref=GeneID:72551452;Name=OPG056;gbkey=Gene;gene=OPG056;gene_biotype=protein_coding;locus_tag=NBT03_gp036;old_locus_tag=MPXV-M5312_HM12_Rivers-040 +NC_063383.1 RefSeq CDS 37127 39034 . - 0 ID=cds-YP_010377039.1;Parent=gene-NBT03_gp036;Dbxref=GenBank:YP_010377039.1,GeneID:72551452;Name=OPG056;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp044%3B actin tail formation%3B EEV maturation protein%3B similar to VACV-WR C18L and VACV-Cop F12L;gbkey=CDS;gene=OPG056;locus_tag=NBT03_gp036;product=EEV maturation protein;protein_id=YP_010377039.1 +NC_063383.1 RefSeq gene 39077 40195 . - . ID=gene-NBT03_gp037;Dbxref=GeneID:72551453;Name=OPG057;gbkey=Gene;gene=OPG057;gene_biotype=protein_coding;locus_tag=NBT03_gp037;old_locus_tag=MPXV-M5312_HM12_Rivers-041 +NC_063383.1 RefSeq CDS 39077 40195 . - 0 ID=cds-YP_010377040.1;Parent=gene-NBT03_gp037;Dbxref=GenBank:YP_010377040.1,GeneID:72551453;Name=OPG057;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp045%3B major envelope antigen of EEV%3B wrapping of IMV to form IEV%3B phospholipase D-like%3B Palmitylated EEV membrane glycoprotein%3B similar to VACV-WR C19L and VACV-Cop F13L;gbkey=CDS;gene=OPG057;locus_tag=NBT03_gp037;product=Palmytilated EEV membrane protein;protein_id=YP_010377040.1 +NC_063383.1 RefSeq gene 40213 40434 . - . ID=gene-NBT03_gp038;Dbxref=GeneID:72551454;Name=OPG058;gbkey=Gene;gene=OPG058;gene_biotype=protein_coding;locus_tag=NBT03_gp038;old_locus_tag=MPXV-M5312_HM12_Rivers-042 +NC_063383.1 RefSeq CDS 40213 40434 . - 0 ID=cds-YP_010377041.1;Parent=gene-NBT03_gp038;Dbxref=GenBank:YP_010377041.1,GeneID:72551454;Name=OPG058;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp046%3B similar to VACV-WR C20L and VACV-Cop F14L;gbkey=CDS;gene=OPG058;locus_tag=NBT03_gp038;product=Protein F14 (1);protein_id=YP_010377041.1 +NC_063383.1 RefSeq gene 40484 40633 . - . ID=gene-NBT03_gp039;Dbxref=GeneID:72551455;Name=OPG059;gbkey=Gene;gene=OPG059;gene_biotype=protein_coding;locus_tag=NBT03_gp039;old_locus_tag=MPXV-M5312_HM12_Rivers-043 +NC_063383.1 RefSeq CDS 40484 40633 . - 0 ID=cds-YP_010377042.1;Parent=gene-NBT03_gp039;Dbxref=GenBank:YP_010377042.1,GeneID:72551455;Name=OPG059;Note=Taxonomic breadth: poxvirinae%3B IMV protein%3B C20.5L%3B similar to VACV-CopF14.5L;gbkey=CDS;gene=OPG059;locus_tag=NBT03_gp039;product=Cytochrome C oxidase;protein_id=YP_010377042.1 +NC_063383.1 RefSeq gene 40706 41182 . - . ID=gene-NBT03_gp040;Dbxref=GeneID:72551456;Name=OPG060;gbkey=Gene;gene=OPG060;gene_biotype=protein_coding;locus_tag=NBT03_gp040;old_locus_tag=MPXV-M5312_HM12_Rivers-044 +NC_063383.1 RefSeq CDS 40706 41182 . - 0 ID=cds-YP_010377043.1;Parent=gene-NBT03_gp040;Dbxref=GenBank:YP_010377043.1,GeneID:72551456;Name=OPG060;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp047%3B Unknown conserved protein%3B similar to VACV-WR C21L and VACV-Cop F15L;gbkey=CDS;gene=OPG060;locus_tag=NBT03_gp040;product=Protein F15;protein_id=YP_010377043.1 +NC_063383.1 RefSeq gene 41189 41884 . - . ID=gene-NBT03_gp041;Dbxref=GeneID:72551457;Name=OPG061;gbkey=Gene;gene=OPG061;gene_biotype=protein_coding;locus_tag=NBT03_gp041;old_locus_tag=MPXV-M5312_HM12_Rivers-045 +NC_063383.1 RefSeq CDS 41189 41884 . - 0 ID=cds-YP_010377044.1;Parent=gene-NBT03_gp041;Dbxref=GenBank:YP_010377044.1,GeneID:72551457;Name=OPG061;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp048%3B Non-functional Serine Recombinase%3B similar to VACV-WR C22L and VACV-Cop F16L;gbkey=CDS;gene=OPG061;locus_tag=NBT03_gp041;product=Protein F16 (1);protein_id=YP_010377044.1 +NC_063383.1 RefSeq gene 41947 42252 . + . ID=gene-NBT03_gp042;Dbxref=GeneID:72551458;Name=OPG062;gbkey=Gene;gene=OPG062;gene_biotype=protein_coding;locus_tag=NBT03_gp042;old_locus_tag=MPXV-M5312_HM12_Rivers-046 +NC_063383.1 RefSeq CDS 41947 42252 . + 0 ID=cds-YP_010377045.1;Parent=gene-NBT03_gp042;Dbxref=GenBank:YP_010377045.1,GeneID:72551458;Name=OPG062;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp049%3B virion core DNA-binding phosphoprotein (VP11)%3B mTOR antagonist%3B similar to VACV-WR C23R and VACV-Cop F17R;gbkey=CDS;gene=OPG062;locus_tag=NBT03_gp042;product=DNA-binding phosphoprotein (1);protein_id=YP_010377045.1 +NC_063383.1 RefSeq gene 42249 43688 . - . ID=gene-NBT03_gp043;Dbxref=GeneID:72551459;Name=OPG063;gbkey=Gene;gene=OPG063;gene_biotype=protein_coding;locus_tag=NBT03_gp043;old_locus_tag=MPXV-M5312_HM12_Rivers-047 +NC_063383.1 RefSeq CDS 42249 43688 . - 0 ID=cds-YP_010377046.1;Parent=gene-NBT03_gp043;Dbxref=GenBank:YP_010377046.1,GeneID:72551459;Name=OPG063;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp050%3B poly-A polymerase%2C Poly (A) polymerase catalytic subunit (VP55)%3B similar to VACV-WR F1L and VACV-Cop E1L;gbkey=CDS;gene=OPG063;locus_tag=NBT03_gp043;product=Poly(A) polymerase catalytic subunit (3);protein_id=YP_010377046.1 +NC_063383.1 RefSeq gene 43685 45898 . - . ID=gene-NBT03_gp044;Dbxref=GeneID:72551460;Name=OPG064;gbkey=Gene;gene=OPG064;gene_biotype=protein_coding;locus_tag=NBT03_gp044;old_locus_tag=MPXV-M5312_HM12_Rivers-048 +NC_063383.1 RefSeq CDS 43685 45898 . - 0 ID=cds-YP_010377047.1;Parent=gene-NBT03_gp044;Dbxref=GenBank:YP_010377047.1,GeneID:72551460;Name=OPG064;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp051%3B IEV morphogenesis%3B similar to VACV-WR F2L and VACV-Cop E2L;gbkey=CDS;gene=OPG064;locus_tag=NBT03_gp044;product=Iev morphogenesis protein;protein_id=YP_010377047.1 +NC_063383.1 RefSeq gene 46022 46483 . - . ID=gene-NBT03_gp045;Dbxref=GeneID:72551461;Name=OPG065;gbkey=Gene;gene=OPG065;gene_biotype=protein_coding;locus_tag=NBT03_gp045;old_locus_tag=MPXV-M5312_HM12_Rivers-049 +NC_063383.1 RefSeq CDS 46022 46483 . - 0 ID=cds-YP_010377048.1;Parent=gene-NBT03_gp045;Dbxref=GenBank:YP_010377048.1,GeneID:72551461;Name=OPG065;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp052%3B interferon resistance factor%3B two forms (25 kDa and 19 kDa) of the dsRNA-binding protein%3B inhibition of dsRNA-dependent protein kinase and 2-5A-synthet%3B dsRNA-binding protein%2C IFN resistance/PKR inhibitor (Z-DNA binding)%3B start of ORF is missing approx. 37 AA compared to CPXVs%3B similar to VACV-WR F3L and VACV-Cop E3L;gbkey=CDS;gene=OPG065;locus_tag=NBT03_gp045;product=Double-stranded RNA binding protein;protein_id=YP_010377048.1 +NC_063383.1 RefSeq gene 46649 47428 . - . ID=gene-NBT03_gp046;Dbxref=GeneID:72551462;Name=OPG066;gbkey=Gene;gene=OPG066;gene_biotype=protein_coding;locus_tag=NBT03_gp046;old_locus_tag=MPXV-M5312_HM12_Rivers-050 +NC_063383.1 RefSeq CDS 46649 47428 . - 0 ID=cds-YP_010377049.1;Parent=gene-NBT03_gp046;Dbxref=GenBank:YP_010377049.1,GeneID:72551462;Name=OPG066;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp053%3B RNA polymerase 30 kDa subunit (RPO30)%3B simultaneously intermediate stage promoter-specific transcription factor%2C VITF-1%3B similar to VACV-WR F4L and VACV-Cop E4L;gbkey=CDS;gene=OPG066;locus_tag=NBT03_gp046;product=DNA-directed RNA polymerase 30 kDa polypeptide;protein_id=YP_010377049.1 +NC_063383.1 RefSeq sequence_feature 47525 48062 . + . ID=id-NC_063383.1:47525..48062;exon_number=OPG067;gbkey=misc_feature;number=OPG067 +NC_063383.1 RefSeq gene 48201 49904 . + . ID=gene-NBT03_gp047;Dbxref=GeneID:72551463;Name=OPG068;gbkey=Gene;gene=OPG068;gene_biotype=protein_coding;locus_tag=NBT03_gp047;old_locus_tag=MPXV-M5312_HM12_Rivers-052 +NC_063383.1 RefSeq CDS 48201 49904 . + 0 ID=cds-YP_010377051.1;Parent=gene-NBT03_gp047;Dbxref=GenBank:YP_010377051.1,GeneID:72551463;Name=OPG068;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp054%3B Virion protein%3B similar to VACV-WR F5R and VACV-Cop E6R;gbkey=CDS;gene=OPG068;locus_tag=NBT03_gp047;product=IMV membrane protein E6;protein_id=YP_010377051.1 +NC_063383.1 RefSeq gene 49986 50486 . + . ID=gene-NBT03_gp048;Dbxref=GeneID:72551464;Name=OPG069;gbkey=Gene;gene=OPG069;gene_biotype=protein_coding;locus_tag=NBT03_gp048;old_locus_tag=MPXV-M5312_HM12_Rivers-053 +NC_063383.1 RefSeq CDS 49986 50486 . + 0 ID=cds-YP_010377052.1;Parent=gene-NBT03_gp048;Dbxref=GenBank:YP_010377052.1,GeneID:72551464;Name=OPG069;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp055%3B soluble myristylated protein%3B similar to VACV-WR F6R and VACV-Cop E7R;gbkey=CDS;gene=OPG069;locus_tag=NBT03_gp048;product=Myristoylated protein E7;protein_id=YP_010377052.1 +NC_063383.1 RefSeq gene 50590 51411 . + . ID=gene-NBT03_gp049;Dbxref=GeneID:72551465;Name=OPG070;gbkey=Gene;gene=OPG070;gene_biotype=protein_coding;locus_tag=NBT03_gp049;old_locus_tag=MPXV-M5312_HM12_Rivers-054 +NC_063383.1 RefSeq CDS 50590 51411 . + 0 ID=cds-YP_010377053.1;Parent=gene-NBT03_gp049;Dbxref=GenBank:YP_010377053.1,GeneID:72551465;Name=OPG070;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp056%3B ER-localized membrane protein%2C virion core protein%3B similar to VACV-WR F7R and VACV-Cop E8R;gbkey=CDS;gene=OPG070;locus_tag=NBT03_gp049;product=Membrane protein E8;protein_id=YP_010377053.1 +NC_063383.1 RefSeq gene 51418 54438 . - . ID=gene-NBT03_gp050;Dbxref=GeneID:72551466;Name=OPG071;gbkey=Gene;gene=OPG071;gene_biotype=protein_coding;locus_tag=NBT03_gp050;old_locus_tag=MPXV-M5312_HM12_Rivers-055 +NC_063383.1 RefSeq CDS 51418 54438 . - 0 ID=cds-YP_010377054.1;Parent=gene-NBT03_gp050;Dbxref=GenBank:YP_010377054.1,GeneID:72551466;Name=OPG071;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp057%3B DNA polymerase%2C catalytic subunit%3B similar to VACV-WR F8L and VACV-Cop E9L;gbkey=CDS;gene=OPG071;locus_tag=NBT03_gp050;product=DNA polymerase (2);protein_id=YP_010377054.1 +NC_063383.1 RefSeq gene 54470 54757 . + . ID=gene-NBT03_gp051;Dbxref=GeneID:72551467;Name=OPG072;gbkey=Gene;gene=OPG072;gene_biotype=protein_coding;locus_tag=NBT03_gp051;old_locus_tag=MPXV-M5312_HM12_Rivers-056 +NC_063383.1 RefSeq CDS 54470 54757 . + 0 ID=cds-YP_010377055.1;Parent=gene-NBT03_gp051;Dbxref=GenBank:YP_010377055.1,GeneID:72551467;Name=OPG072;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp058%3B protein disulfide bond-forming enzyme%3B Sulfhydryl oxidase (FAD-linked)%3B similar to VACV-WR F9R and VACV-Cop E10R;gbkey=CDS;gene=OPG072;locus_tag=NBT03_gp051;product=Sulfhydryl oxidase;protein_id=YP_010377055.1 +NC_063383.1 RefSeq gene 54752 55141 . - . ID=gene-NBT03_gp052;Dbxref=GeneID:72551468;Name=OPG073;gbkey=Gene;gene=OPG073;gene_biotype=protein_coding;locus_tag=NBT03_gp052;old_locus_tag=MPXV-M5312_HM12_Rivers-057 +NC_063383.1 RefSeq CDS 54752 55141 . - 0 ID=cds-YP_010377056.1;Parent=gene-NBT03_gp052;Dbxref=GenBank:YP_010377056.1,GeneID:72551468;Name=OPG073;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp059%3B virion core protein%3B similar to VACV-WR F10L and VACV-Cop E11L;gbkey=CDS;gene=OPG073;locus_tag=NBT03_gp052;product=Virion core protein E11;protein_id=YP_010377056.1 +NC_063383.1 RefSeq gene 55128 57125 . - . ID=gene-NBT03_gp053;Dbxref=GeneID:72551469;Name=OPG074;gbkey=Gene;gene=OPG074;gene_biotype=protein_coding;locus_tag=NBT03_gp053;old_locus_tag=MPXV-M5312_HM12_Rivers-058 +NC_063383.1 RefSeq CDS 55128 57125 . - 0 ID=cds-YP_010377057.1;Parent=gene-NBT03_gp053;Dbxref=GenBank:YP_010377057.1,GeneID:72551469;Name=OPG074;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp060%3B Membrane protein%3B similar to VACV-WR Q1L and VACV-Cop O1L;gbkey=CDS;gene=OPG074;locus_tag=NBT03_gp053;product=Iev morphogenesis protein;protein_id=YP_010377057.1 +NC_063383.1 RefSeq gene 57172 57498 . - . ID=gene-NBT03_gp054;Dbxref=GeneID:72551470;Name=OPG075;gbkey=Gene;gene=OPG075;gene_biotype=protein_coding;locus_tag=NBT03_gp054;old_locus_tag=MPXV-M5312_HM12_Rivers-059 +NC_063383.1 RefSeq CDS 57172 57498 . - 0 ID=cds-YP_010377058.1;Parent=gene-NBT03_gp054;Dbxref=GenBank:YP_010377058.1,GeneID:72551470;Name=OPG075;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp061%3B virion-associated glutaredoxin%3B glutaredoxin 1%3B similar to VACV-WR Q2L and VACV-Cop O2L;gbkey=CDS;gene=OPG075;locus_tag=NBT03_gp054;product=Glutaredoxin-1;protein_id=YP_010377058.1 +NC_063383.1 RefSeq gene 57523 57630 . - . ID=gene-NBT03_gp055;Dbxref=GeneID:72551471;Name=OPG076;gbkey=Gene;gene=OPG076;gene_biotype=protein_coding;locus_tag=NBT03_gp055 +NC_063383.1 RefSeq CDS 57523 57630 . - 0 ID=cds-YP_010377183.1;Parent=gene-NBT03_gp055;Dbxref=GenBank:YP_010377183.1,GeneID:72551471;Name=OPG076;gbkey=CDS;gene=OPG076;locus_tag=NBT03_gp055;product=MV membrane EFC component;protein_id=YP_010377183.1 +NC_063383.1 RefSeq gene 57645 58583 . - . ID=gene-NBT03_gp056;Dbxref=GeneID:72551472;Name=OPG077;gbkey=Gene;gene=OPG077;gene_biotype=protein_coding;locus_tag=NBT03_gp056;old_locus_tag=MPXV-M5312_HM12_Rivers-060 +NC_063383.1 RefSeq CDS 57645 58583 . - 0 ID=cds-YP_010377059.1;Parent=gene-NBT03_gp056;Dbxref=GenBank:YP_010377059.1,GeneID:72551472;Name=OPG077;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp062%3B virosomal protein essential for virus multiplication%3B DNA-binding core protein%3B similar to VACV-WR I1L and VACV-Cop I1L;gbkey=CDS;gene=OPG077;locus_tag=NBT03_gp056;product=Telomere-binding protein I1;protein_id=YP_010377059.1 +NC_063383.1 RefSeq gene 58590 58811 . - . ID=gene-NBT03_gp057;Dbxref=GeneID:72551473;Name=OPG078;gbkey=Gene;gene=OPG078;gene_biotype=protein_coding;locus_tag=NBT03_gp057;old_locus_tag=MPXV-M5312_HM12_Rivers-061 +NC_063383.1 RefSeq CDS 58590 58811 . - 0 ID=cds-YP_010377060.1;Parent=gene-NBT03_gp057;Dbxref=GenBank:YP_010377060.1,GeneID:72551473;Name=OPG078;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp063%3B IMV membrane protein%3B similar to VACV-WR I2L and VACV-Cop I2L;gbkey=CDS;gene=OPG078;locus_tag=NBT03_gp057;product=IMV membrane protein I2;protein_id=YP_010377060.1 +NC_063383.1 RefSeq gene 58812 59621 . - . ID=gene-NBT03_gp058;Dbxref=GeneID:72551474;Name=OPG079;gbkey=Gene;gene=OPG079;gene_biotype=protein_coding;locus_tag=NBT03_gp058;old_locus_tag=MPXV-M5312_HM12_Rivers-062 +NC_063383.1 RefSeq CDS 58812 59621 . - 0 ID=cds-YP_010377061.1;Parent=gene-NBT03_gp058;Dbxref=GenBank:YP_010377061.1,GeneID:72551474;Name=OPG079;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp064%3B virosomal ssDNA-binding phosphoprotein%3B interacts with R2 subunit of ribonucleotide reductase%3B similar to VACV-WR I3L and VACV-Cop I3L;gbkey=CDS;gene=OPG079;locus_tag=NBT03_gp058;product=DNA-binding phosphoprotein (2);protein_id=YP_010377061.1 +NC_063383.1 RefSeq gene 59703 62018 . - . ID=gene-NBT03_gp059;Dbxref=GeneID:72551475;Name=OPG080;gbkey=Gene;gene=OPG080;gene_biotype=protein_coding;locus_tag=NBT03_gp059;old_locus_tag=MPXV-M5312_HM12_Rivers-063 +NC_063383.1 RefSeq CDS 59703 62018 . - 0 ID=cds-YP_010377062.1;Parent=gene-NBT03_gp059;Dbxref=GenBank:YP_010377062.1,GeneID:72551475;Name=OPG080;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp065%3B ribonucleotide reductase%2C large subunit%2C R1%3B similar to VACV-WR I4L and VACV-Cop I4L;gbkey=CDS;gene=OPG080;locus_tag=NBT03_gp059;product=Ribonucleoside-diphosphate reductase (2);protein_id=YP_010377062.1 +NC_063383.1 RefSeq gene 62046 62285 . - . ID=gene-NBT03_gp060;Dbxref=GeneID:72551476;Name=OPG081;gbkey=Gene;gene=OPG081;gene_biotype=protein_coding;locus_tag=NBT03_gp060;old_locus_tag=MPXV-M5312_HM12_Rivers-064 +NC_063383.1 RefSeq CDS 62046 62285 . - 0 ID=cds-YP_010377063.1;Parent=gene-NBT03_gp060;Dbxref=GenBank:YP_010377063.1,GeneID:72551476;Name=OPG081;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp066%3B IMV surface membrane protein%2C VP13%3B similar to VACV-WR I5L and VACV-Cop I5L;gbkey=CDS;gene=OPG081;locus_tag=NBT03_gp060;product=IMV membrane protein I5;protein_id=YP_010377063.1 +NC_063383.1 RefSeq gene 62304 63452 . - . ID=gene-NBT03_gp061;Dbxref=GeneID:72551477;Name=OPG082;gbkey=Gene;gene=OPG082;gene_biotype=protein_coding;locus_tag=NBT03_gp061;old_locus_tag=MPXV-M5312_HM12_Rivers-065 +NC_063383.1 RefSeq CDS 62304 63452 . - 0 ID=cds-YP_010377064.1;Parent=gene-NBT03_gp061;Dbxref=GenBank:YP_010377064.1,GeneID:72551477;Name=OPG082;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp067%3B Telomere-binding protein%3B similar to VACV-WR I6L and VACV-Cop I6L;gbkey=CDS;gene=OPG082;locus_tag=NBT03_gp061;product=Telomere-binding protein;protein_id=YP_010377064.1 +NC_063383.1 RefSeq gene 63445 64716 . - . ID=gene-NBT03_gp062;Dbxref=GeneID:72551478;Name=OPG083;gbkey=Gene;gene=OPG083;gene_biotype=protein_coding;locus_tag=NBT03_gp062;old_locus_tag=MPXV-M5312_HM12_Rivers-066 +NC_063383.1 RefSeq CDS 63445 64716 . - 0 ID=cds-YP_010377065.1;Parent=gene-NBT03_gp062;Dbxref=GenBank:YP_010377065.1,GeneID:72551478;Name=OPG083;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp068%3B virion core protein%3B similar to DNA topoisomerase II%3B Virion core cysteine protease%3B similar to VACV-WR I7L and VACV-Cop I7L;gbkey=CDS;gene=OPG083;locus_tag=NBT03_gp062;product=Viral core cysteine proteinase;protein_id=YP_010377065.1 +NC_063383.1 RefSeq gene 64722 66752 . + . ID=gene-NBT03_gp063;Dbxref=GeneID:72551479;Name=OPG084;gbkey=Gene;gene=OPG084;gene_biotype=protein_coding;locus_tag=NBT03_gp063;old_locus_tag=MPXV-M5312_HM12_Rivers-067 +NC_063383.1 RefSeq CDS 64722 66752 . + 0 ID=cds-YP_010377066.1;Parent=gene-NBT03_gp063;Dbxref=GenBank:YP_010377066.1,GeneID:72551479;Name=OPG084;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp069%3B nucleoside triphosphate phosphohydrolase II%2C NPH-II%3B DNA and RNA helicase%3B DExH-NPH-II domain%3B similar to VACV-WR I8R and VACV-Cop I8R;gbkey=CDS;gene=OPG084;locus_tag=NBT03_gp063;product=RNA helicase NPH-II (2);protein_id=YP_010377066.1 +NC_063383.1 RefSeq gene 66756 68531 . - . ID=gene-NBT03_gp064;Dbxref=GeneID:72551480;Name=OPG085;gbkey=Gene;gene=OPG085;gene_biotype=protein_coding;locus_tag=NBT03_gp064;old_locus_tag=MPXV-M5312_HM12_Rivers-068 +NC_063383.1 RefSeq CDS 66756 68531 . - 0 ID=cds-YP_010377067.1;Parent=gene-NBT03_gp064;Dbxref=GenBank:YP_010377067.1,GeneID:72551480;Name=OPG085;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp070%3B proteinase%3B Metalloprotease%3B similar to VACV-WR G1L and VACV-Cop G1L;gbkey=CDS;gene=OPG085;locus_tag=NBT03_gp064;product=Metalloendopeptidase;protein_id=YP_010377067.1 +NC_063383.1 RefSeq gene 68528 68863 . - . ID=gene-NBT03_gp065;Dbxref=GeneID:72551481;Name=OPG086;gbkey=Gene;gene=OPG086;gene_biotype=protein_coding;locus_tag=NBT03_gp065;old_locus_tag=MPXV-M5312_HM12_Rivers-069 +NC_063383.1 RefSeq CDS 68528 68863 . - 0 ID=cds-YP_010377068.1;Parent=gene-NBT03_gp065;Dbxref=GenBank:YP_010377068.1,GeneID:72551481;Name=OPG086;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp071%3B Entry/fusion complex component%3B similar to VACV-WR G2L and VACV-Cop G3L;gbkey=CDS;gene=OPG086;locus_tag=NBT03_gp065;product=Entry/fusion complex component;protein_id=YP_010377068.1 +NC_063383.1 RefSeq gene 68857 69519 . + . ID=gene-NBT03_gp066;Dbxref=GeneID:72551482;Name=OPG087;gbkey=Gene;gene=OPG087;gene_biotype=protein_coding;locus_tag=NBT03_gp066;old_locus_tag=MPXV-M5312_HM12_Rivers-070 +NC_063383.1 RefSeq CDS 68857 69519 . + 0 ID=cds-YP_010377069.1;Parent=gene-NBT03_gp066;Dbxref=GenBank:YP_010377069.1,GeneID:72551482;Name=OPG087;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp072%3B VLTF (late transcription elongation factor)%3B similar to VACV-WR G3R and VACV-Cop G2R;gbkey=CDS;gene=OPG087;locus_tag=NBT03_gp066;product=Late transcription elongation factor;protein_id=YP_010377069.1 +NC_063383.1 RefSeq gene 69489 69863 . - . ID=gene-NBT03_gp067;Dbxref=GeneID:72551483;Name=OPG088;gbkey=Gene;gene=OPG088;gene_biotype=protein_coding;locus_tag=NBT03_gp067;old_locus_tag=MPXV-M5312_HM12_Rivers-071 +NC_063383.1 RefSeq CDS 69489 69863 . - 0 ID=cds-YP_010377070.1;Parent=gene-NBT03_gp067;Dbxref=GenBank:YP_010377070.1,GeneID:72551483;Name=OPG088;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp073%3B virion-associated glutaredoxin%3B Glutaredoxin-like protein%3B similar to VACV-WR G4L and VACV-Cop G4L;gbkey=CDS;gene=OPG088;locus_tag=NBT03_gp067;product=Glutaredoxin-2;protein_id=YP_010377070.1 +NC_063383.1 RefSeq gene 69866 71170 . + . ID=gene-NBT03_gp068;Dbxref=GeneID:72551484;Name=OPG089;gbkey=Gene;gene=OPG089;gene_biotype=protein_coding;locus_tag=NBT03_gp068;old_locus_tag=MPXV-M5312_HM12_Rivers-072 +NC_063383.1 RefSeq CDS 69866 71170 . + 0 ID=cds-YP_010377071.1;Parent=gene-NBT03_gp068;Dbxref=GenBank:YP_010377071.1,GeneID:72551484;Name=OPG089;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp074%3B FEN1-like nuclease%3B similar to VACV-WR G5R and VACV-Cop G5R;gbkey=CDS;gene=OPG089;locus_tag=NBT03_gp068;product=FEN1-like nuclease;protein_id=YP_010377071.1 +NC_063383.1 RefSeq gene 71179 71370 . + . ID=gene-NBT03_gp069;Dbxref=GeneID:72551485;Name=OPG090;gbkey=Gene;gene=OPG090;gene_biotype=protein_coding;locus_tag=NBT03_gp069;old_locus_tag=MPXV-M5312_HM12_Rivers-073 +NC_063383.1 RefSeq CDS 71179 71370 . + 0 ID=cds-YP_010377072.1;Parent=gene-NBT03_gp069;Dbxref=GenBank:YP_010377072.1,GeneID:72551485;Name=OPG090;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp075%3B RNA polymerase subunit%2C 7 kDa subunit (RPO7)%3B similar to VACV-WR G6R and VACV-Cop G5.5R;gbkey=CDS;gene=OPG090;locus_tag=NBT03_gp069;product=DNA-directed RNA polymerase 7 kDa subunit;protein_id=YP_010377072.1 +NC_063383.1 RefSeq gene 71370 71867 . + . ID=gene-NBT03_gp070;Dbxref=GeneID:72551486;Name=OPG091;gbkey=Gene;gene=OPG091;gene_biotype=protein_coding;locus_tag=NBT03_gp070;old_locus_tag=MPXV-M5312_HM12_Rivers-074 +NC_063383.1 RefSeq CDS 71370 71867 . + 0 ID=cds-YP_010377073.1;Parent=gene-NBT03_gp070;Dbxref=GenBank:YP_010377073.1,GeneID:72551486;Name=OPG091;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp076%3B NLPc/P60 superfamily protein%3B similar to VACV-WR G7R and VACV-Cop G6R;gbkey=CDS;gene=OPG091;locus_tag=NBT03_gp070;product=Nlpc/p60 superfamily protein;protein_id=YP_010377073.1 +NC_063383.1 RefSeq gene 71832 72947 . - . ID=gene-NBT03_gp071;Dbxref=GeneID:72551487;Name=OPG092;gbkey=Gene;gene=OPG092;gene_biotype=protein_coding;locus_tag=NBT03_gp071;old_locus_tag=MPXV-M5312_HM12_Rivers-075 +NC_063383.1 RefSeq CDS 71832 72947 . - 0 ID=cds-YP_010377074.1;Parent=gene-NBT03_gp071;Dbxref=GenBank:YP_010377074.1,GeneID:72551487;Name=OPG092;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp077%3B virion protein%3B Virion phosphoprotein%2C early morphogenesis%3B similar to VACV-WR G8L and VACV-Cop G7L;gbkey=CDS;gene=OPG092;locus_tag=NBT03_gp071;product=Assembly protein G7;protein_id=YP_010377074.1 +NC_063383.1 RefSeq gene 72978 73760 . + . ID=gene-NBT03_gp072;Dbxref=GeneID:72551488;Name=OPG093;gbkey=Gene;gene=OPG093;gene_biotype=protein_coding;locus_tag=NBT03_gp072;old_locus_tag=MPXV-M5312_HM12_Rivers-076 +NC_063383.1 RefSeq CDS 72978 73760 . + 0 ID=cds-YP_010377075.1;Parent=gene-NBT03_gp072;Dbxref=GenBank:YP_010377075.1,GeneID:72551488;Name=OPG093;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp078%3B late gene transcription factor%2C VLTF-1%3B similar to VACV-WR G9R and VACV-Cop G8R;gbkey=CDS;gene=OPG093;locus_tag=NBT03_gp072;product=Late transcription factor VLTF-1;protein_id=YP_010377075.1 +NC_063383.1 RefSeq gene 73780 74802 . + . ID=gene-NBT03_gp073;Dbxref=GeneID:72551489;Name=OPG094;gbkey=Gene;gene=OPG094;gene_biotype=protein_coding;locus_tag=NBT03_gp073;old_locus_tag=MPXV-M5312_HM12_Rivers-077 +NC_063383.1 RefSeq CDS 73780 74802 . + 0 ID=cds-YP_010377076.1;Parent=gene-NBT03_gp073;Dbxref=GenBank:YP_010377076.1,GeneID:72551489;Name=OPG094;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp079%3B myristylated protein%3B Entry/fusion complex component%2C myristylprotein%3B similar to VACV-WR G10R and VACV-Cop G9R;gbkey=CDS;gene=OPG094;locus_tag=NBT03_gp073;product=Myristylated protein;protein_id=YP_010377076.1 +NC_063383.1 RefSeq gene 74803 75555 . + . ID=gene-NBT03_gp074;Dbxref=GeneID:72551490;Name=OPG095;gbkey=Gene;gene=OPG095;gene_biotype=protein_coding;locus_tag=NBT03_gp074;old_locus_tag=MPXV-M5312_HM12_Rivers-078 +NC_063383.1 RefSeq CDS 74803 75555 . + 0 ID=cds-YP_010377077.1;Parent=gene-NBT03_gp074;Dbxref=GenBank:YP_010377077.1,GeneID:72551490;Name=OPG095;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp080%3B myristylated IMV surface membrane protein%3B similar to VACV-WR M1R and VACV-Cop L1R;gbkey=CDS;gene=OPG095;locus_tag=NBT03_gp074;product=IMV membrane protein L1R;protein_id=YP_010377077.1 +NC_063383.1 RefSeq gene 75587 75865 . + . ID=gene-NBT03_gp075;Dbxref=GeneID:72551491;Name=OPG096;gbkey=Gene;gene=OPG096;gene_biotype=protein_coding;locus_tag=NBT03_gp075;old_locus_tag=MPXV-M5312_HM12_Rivers-079 +NC_063383.1 RefSeq CDS 75587 75865 . + 0 ID=cds-YP_010377078.1;Parent=gene-NBT03_gp075;Dbxref=GenBank:YP_010377078.1,GeneID:72551491;Name=OPG096;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp081%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR M2R and VACV-Cop L2R;gbkey=CDS;gene=OPG096;locus_tag=NBT03_gp075;product=Crescent membrane and immature virion formation protein;protein_id=YP_010377078.1 +NC_063383.1 RefSeq gene 75841 76875 . - . ID=gene-NBT03_gp076;Dbxref=GeneID:72551492;Name=OPG097;gbkey=Gene;gene=OPG097;gene_biotype=protein_coding;locus_tag=NBT03_gp076;old_locus_tag=MPXV-M5312_HM12_Rivers-080 +NC_063383.1 RefSeq CDS 75841 76875 . - 0 ID=cds-YP_010377079.1;Parent=gene-NBT03_gp076;Dbxref=GenBank:YP_010377079.1,GeneID:72551492;Name=OPG097;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp082%3B Internal virion protein%3B similar to VACV-WR M3L and VACV-Cop L3L;gbkey=CDS;gene=OPG097;locus_tag=NBT03_gp076;product=Internal virion L3/FP4 protein;protein_id=YP_010377079.1 +NC_063383.1 RefSeq gene 76900 77655 . + . ID=gene-NBT03_gp077;Dbxref=GeneID:72551493;Name=OPG098;gbkey=Gene;gene=OPG098;gene_biotype=protein_coding;locus_tag=NBT03_gp077;old_locus_tag=MPXV-M5312_HM12_Rivers-081 +NC_063383.1 RefSeq CDS 76900 77655 . + 0 ID=cds-YP_010377080.1;Parent=gene-NBT03_gp077;Dbxref=GenBank:YP_010377080.1,GeneID:72551493;Name=OPG098;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp083%3B virion core protein vp8%3B stimulation of I8R helicase activity%3B ss/dsDNA binding protein (VP8)%3B similar to VACV-WR M4R and VACV-Cop L4R;gbkey=CDS;gene=OPG098;locus_tag=NBT03_gp077;product=Nucleic acid binding protein VP8/L4R;protein_id=YP_010377080.1 +NC_063383.1 RefSeq gene 77665 78051 . + . ID=gene-NBT03_gp078;Dbxref=GeneID:72551494;Name=OPG099;gbkey=Gene;gene=OPG099;gene_biotype=protein_coding;locus_tag=NBT03_gp078;old_locus_tag=MPXV-M5312_HM12_Rivers-082 +NC_063383.1 RefSeq CDS 77665 78051 . + 0 ID=cds-YP_010377081.1;Parent=gene-NBT03_gp078;Dbxref=GenBank:YP_010377081.1,GeneID:72551494;Name=OPG099;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp084%3B Entry and Fusion IMV protein%3B similar to VACV-WR M5R and VACV-Cop L5R;gbkey=CDS;gene=OPG099;locus_tag=NBT03_gp078;product=Membrane protein CL5;protein_id=YP_010377081.1 +NC_063383.1 RefSeq gene 78008 78466 . + . ID=gene-NBT03_gp079;Dbxref=GeneID:72551495;Name=OPG100;gbkey=Gene;gene=OPG100;gene_biotype=protein_coding;locus_tag=NBT03_gp079;old_locus_tag=MPXV-M5312_HM12_Rivers-083 +NC_063383.1 RefSeq CDS 78008 78466 . + 0 ID=cds-YP_010377082.1;Parent=gene-NBT03_gp079;Dbxref=GenBank:YP_010377082.1,GeneID:72551495;Name=OPG100;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp085%3B Virion morph%3B similar to VACV-WR L1R and VACV-Cop J1R;gbkey=CDS;gene=OPG100;locus_tag=NBT03_gp079;product=IMV membrane protein J1;protein_id=YP_010377082.1 +NC_063383.1 RefSeq gene 78486 79019 . + . ID=gene-NBT03_gp080;Dbxref=GeneID:72551496;Name=OPG101;gbkey=Gene;gene=OPG101;gene_biotype=protein_coding;locus_tag=NBT03_gp080;old_locus_tag=MPXV-M5312_HM12_Rivers-084 +NC_063383.1 RefSeq CDS 78486 79019 . + 0 ID=cds-YP_010377083.1;Parent=gene-NBT03_gp080;Dbxref=GenBank:YP_010377083.1,GeneID:72551496;Name=OPG101;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp086%3B thymidine kinase%3B similar to VACV-WR L2R and VACV-Cop J2R;gbkey=CDS;gene=OPG101;locus_tag=NBT03_gp080;product=Thymidine kinase;protein_id=YP_010377083.1 +NC_063383.1 RefSeq gene 79085 80086 . + . ID=gene-NBT03_gp081;Dbxref=GeneID:72551497;Name=OPG102;gbkey=Gene;gene=OPG102;gene_biotype=protein_coding;locus_tag=NBT03_gp081;old_locus_tag=MPXV-M5312_HM12_Rivers-085 +NC_063383.1 RefSeq CDS 79085 80086 . + 0 ID=cds-YP_010377084.1;Parent=gene-NBT03_gp081;Dbxref=GenBank:YP_010377084.1,GeneID:72551497;Name=OPG102;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp087%3B poly-A polymerase%2C stimulatory subunit%2C simultaneously cap-specific mRNA (nucleoside-O2'-)-methyltransferase%3B Poly (A) polymerase small subunit (VP39)%3B similar to VACV-WR L3R and VACV-Cop J3R;gbkey=CDS;gene=OPG102;locus_tag=NBT03_gp081;product=Cap-specific mRNA;protein_id=YP_010377084.1 +NC_063383.1 RefSeq gene 80001 80558 . + . ID=gene-NBT03_gp082;Dbxref=GeneID:72551498;Name=OPG103;gbkey=Gene;gene=OPG103;gene_biotype=protein_coding;locus_tag=NBT03_gp082;old_locus_tag=MPXV-M5312_HM12_Rivers-086 +NC_063383.1 RefSeq CDS 80001 80558 . + 0 ID=cds-YP_010377085.1;Parent=gene-NBT03_gp082;Dbxref=GenBank:YP_010377085.1,GeneID:72551498;Name=OPG103;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp088%3B RNA polymerase%2C 22 kDa subunit (RPO22)%3B similar to VACV-WR L4R and VACV-Cop J4R;gbkey=CDS;gene=OPG103;locus_tag=NBT03_gp082;product=DNA-directed RNA polymerase subunit;protein_id=YP_010377085.1 +NC_063383.1 RefSeq gene 80618 81019 . - . ID=gene-NBT03_gp083;Dbxref=GeneID:72551499;Name=OPG104;gbkey=Gene;gene=OPG104;gene_biotype=protein_coding;locus_tag=NBT03_gp083;old_locus_tag=MPXV-M5312_HM12_Rivers-087 +NC_063383.1 RefSeq CDS 80618 81019 . - 0 ID=cds-YP_010377086.1;Parent=gene-NBT03_gp083;Dbxref=GenBank:YP_010377086.1,GeneID:72551499;Name=OPG104;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp089%3B essential for virus multiplication%3B IMV membrane protein%3B similar to VACV-WR L5L and VACV-Cop J5L;gbkey=CDS;gene=OPG104;locus_tag=NBT03_gp083;product=Myristylated protein;protein_id=YP_010377086.1 +NC_063383.1 RefSeq gene 81126 84986 . + . ID=gene-NBT03_gp084;Dbxref=GeneID:72551500;Name=OPG105;gbkey=Gene;gene=OPG105;gene_biotype=protein_coding;locus_tag=NBT03_gp084;old_locus_tag=MPXV-M5312_HM12_Rivers-088 +NC_063383.1 RefSeq CDS 81126 84986 . + 0 ID=cds-YP_010377087.1;Parent=gene-NBT03_gp084;Dbxref=GenBank:YP_010377087.1,GeneID:72551500;Name=OPG105;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp090%3B RNA polymerase%2C 147 kDa subunit (RPO147)%3B similar to VACV-WR L6R and VACV-Cop J6R;gbkey=CDS;gene=OPG105;locus_tag=NBT03_gp084;product=DNA-dependent RNA polymerase subunit rpo147;protein_id=YP_010377087.1 +NC_063383.1 RefSeq gene 84983 85498 . - . ID=gene-NBT03_gp085;Dbxref=GeneID:72551501;Name=OPG106;gbkey=Gene;gene=OPG106;gene_biotype=protein_coding;locus_tag=NBT03_gp085;old_locus_tag=MPXV-M5312_HM12_Rivers-089 +NC_063383.1 RefSeq CDS 84983 85498 . - 0 ID=cds-YP_010377088.1;Parent=gene-NBT03_gp085;Dbxref=GenBank:YP_010377088.1,GeneID:72551501;Name=OPG106;Note=Taxonomic breadth: poxvirinae%3B Old product: MPXVgp091%3B tyrosine%3B Tyr/Ser phosphatase%2C IFN-gamma inhibitor%3B similar to VACV-WR H1L and VACV-Cop H1L;gbkey=CDS;gene=OPG106;locus_tag=NBT03_gp085;product=Tyr/ser protein phosphatase;protein_id=YP_010377088.1 +NC_063383.1 RefSeq gene 85512 86081 . + . ID=gene-NBT03_gp086;Dbxref=GeneID:72551502;Name=OPG107;gbkey=Gene;gene=OPG107;gene_biotype=protein_coding;locus_tag=NBT03_gp086;old_locus_tag=MPXV-M5312_HM12_Rivers-090 +NC_063383.1 RefSeq CDS 85512 86081 . + 0 ID=cds-YP_010377089.1;Parent=gene-NBT03_gp086;Dbxref=GenBank:YP_010377089.1,GeneID:72551502;Name=OPG107;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp092%3B IMV membrane protein%3B similar to VACV-WR H2R and VACV-Cop H2R;gbkey=CDS;gene=OPG107;locus_tag=NBT03_gp086;product=Entry-fusion complex essential component;protein_id=YP_010377089.1 +NC_063383.1 RefSeq gene 86085 87059 . - . ID=gene-NBT03_gp087;Dbxref=GeneID:72551503;Name=OPG108;gbkey=Gene;gene=OPG108;gene_biotype=protein_coding;locus_tag=NBT03_gp087;old_locus_tag=MPXV-M5312_HM12_Rivers-091 +NC_063383.1 RefSeq CDS 86085 87059 . - 0 ID=cds-YP_010377090.1;Parent=gene-NBT03_gp087;Dbxref=GenBank:YP_010377090.1,GeneID:72551503;Name=OPG108;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp093%3B IMV surface membrane protein%3B IMV heparin binding surface protein%3B similar to VACV-WR H3L and VACV-Cop H3L;gbkey=CDS;gene=OPG108;locus_tag=NBT03_gp087;product=IMV heparin binding surface protein;protein_id=YP_010377090.1 +NC_063383.1 RefSeq gene 87060 89447 . - . ID=gene-NBT03_gp088;Dbxref=GeneID:72551504;Name=OPG109;gbkey=Gene;gene=OPG109;gene_biotype=protein_coding;locus_tag=NBT03_gp088;old_locus_tag=MPXV-M5312_HM12_Rivers-092 +NC_063383.1 RefSeq CDS 87060 89447 . - 0 ID=cds-YP_010377091.1;Parent=gene-NBT03_gp088;Dbxref=GenBank:YP_010377091.1,GeneID:72551504;Name=OPG109;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp094%3B virion core RNA polymerase-associated protein%2C RAP94%3B similar to VACV-WR H4L and VACV-Cop H4L;gbkey=CDS;gene=OPG109;locus_tag=NBT03_gp088;product=RNA polymerase-associated transcription-specificity factor RAP94;protein_id=YP_010377091.1 +NC_063383.1 RefSeq gene 89632 90264 . + . ID=gene-NBT03_gp089;Dbxref=GeneID:72551505;Name=OPG110;gbkey=Gene;gene=OPG110;gene_biotype=protein_coding;locus_tag=NBT03_gp089;old_locus_tag=MPXV-M5312_HM12_Rivers-093 +NC_063383.1 RefSeq CDS 89632 90264 . + 0 ID=cds-YP_010377092.1;Parent=gene-NBT03_gp089;Dbxref=GenBank:YP_010377092.1,GeneID:72551505;Name=OPG110;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp095%3B virosome-associated late gene transcription factor%2C VLTF-4%3B Ca2+-binding motif%3B similar to VACV-WR H5R and VACV-Cop H5R;gbkey=CDS;gene=OPG110;locus_tag=NBT03_gp089;product=Late transcription factor VLTF-4 (1);protein_id=YP_010377092.1 +NC_063383.1 RefSeq gene 90265 91209 . + . ID=gene-NBT03_gp090;Dbxref=GeneID:72551506;Name=OPG111;gbkey=Gene;gene=OPG111;gene_biotype=protein_coding;locus_tag=NBT03_gp090;old_locus_tag=MPXV-M5312_HM12_Rivers-094 +NC_063383.1 RefSeq CDS 90265 91209 . + 0 ID=cds-YP_010377093.1;Parent=gene-NBT03_gp090;Dbxref=GenBank:YP_010377093.1,GeneID:72551506;Name=OPG111;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp096%3B DNA topoisomerase type I%3B similar to VACV-WR H6R and VACV-Cop H6R;gbkey=CDS;gene=OPG111;locus_tag=NBT03_gp090;product=DNA topoisomerase type I;protein_id=YP_010377093.1 +NC_063383.1 RefSeq gene 91247 91687 . + . ID=gene-NBT03_gp091;Dbxref=GeneID:72551507;Name=OPG112;gbkey=Gene;gene=OPG112;gene_biotype=protein_coding;locus_tag=NBT03_gp091;old_locus_tag=MPXV-M5312_HM12_Rivers-095 +NC_063383.1 RefSeq CDS 91247 91687 . + 0 ID=cds-YP_010377094.1;Parent=gene-NBT03_gp091;Dbxref=GenBank:YP_010377094.1,GeneID:72551507;Name=OPG112;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp097%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR H7R and VACV-Cop H7R;gbkey=CDS;gene=OPG112;locus_tag=NBT03_gp091;product=Late protein H7;protein_id=YP_010377094.1 +NC_063383.1 RefSeq gene 91731 94268 . + . ID=gene-NBT03_gp092;Dbxref=GeneID:72551508;Name=OPG113;gbkey=Gene;gene=OPG113;gene_biotype=protein_coding;locus_tag=NBT03_gp092;old_locus_tag=MPXV-M5312_HM12_Rivers-096 +NC_063383.1 RefSeq CDS 91731 94268 . + 0 ID=cds-YP_010377095.1;Parent=gene-NBT03_gp092;Dbxref=GenBank:YP_010377095.1,GeneID:72551508;Name=OPG113;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp098%3B mRNA capping enzyme%2C large subunit%3B RNA 5' triphosphatase and RNA guanylyl transferase activities%3B similar to VACV-WR E1R and VACV-Cop D1R;gbkey=CDS;gene=OPG113;locus_tag=NBT03_gp092;product=mRNA capping enzyme large subunit;protein_id=YP_010377095.1 +NC_063383.1 RefSeq gene 94227 94667 . - . ID=gene-NBT03_gp093;Dbxref=GeneID:72551509;Name=OPG114;gbkey=Gene;gene=OPG114;gene_biotype=protein_coding;locus_tag=NBT03_gp093;old_locus_tag=MPXV-M5312_HM12_Rivers-097 +NC_063383.1 RefSeq CDS 94227 94667 . - 0 ID=cds-YP_010377096.1;Parent=gene-NBT03_gp093;Dbxref=GenBank:YP_010377096.1,GeneID:72551509;Name=OPG114;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp099%3B virion core protein%3B similar to VACV-WR E2L and VACV-Cop D2L;gbkey=CDS;gene=OPG114;locus_tag=NBT03_gp093;product=Virion protein D2;protein_id=YP_010377096.1 +NC_063383.1 RefSeq gene 94660 95361 . + . ID=gene-NBT03_gp094;Dbxref=GeneID:72551510;Name=OPG115;gbkey=Gene;gene=OPG115;gene_biotype=protein_coding;locus_tag=NBT03_gp094;old_locus_tag=MPXV-M5312_HM12_Rivers-098 +NC_063383.1 RefSeq CDS 94660 95361 . + 0 ID=cds-YP_010377097.1;Parent=gene-NBT03_gp094;Dbxref=GenBank:YP_010377097.1,GeneID:72551510;Name=OPG115;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp100%3B virion core protein%3B similar to VACV-WR E3R and VACV-Cop D3R;gbkey=CDS;gene=OPG115;locus_tag=NBT03_gp094;product=Virion core protein D3;protein_id=YP_010377097.1 +NC_063383.1 RefSeq gene 95361 96017 . + . ID=gene-NBT03_gp095;Dbxref=GeneID:72551511;Name=OPG116;gbkey=Gene;gene=OPG116;gene_biotype=protein_coding;locus_tag=NBT03_gp095;old_locus_tag=MPXV-M5312_HM12_Rivers-099 +NC_063383.1 RefSeq CDS 95361 96017 . + 0 ID=cds-YP_010377098.1;Parent=gene-NBT03_gp095;Dbxref=GenBank:YP_010377098.1,GeneID:72551511;Name=OPG116;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp101%3B uracil DNA glycosylase%3B DNA polymerase processivity factor%3B similar to VACV-WR E4R and VACV-Cop D4R;gbkey=CDS;gene=OPG116;locus_tag=NBT03_gp095;product=Uracil DNA glycosylase superfamily;protein_id=YP_010377098.1 +NC_063383.1 RefSeq gene 96049 98406 . + . ID=gene-NBT03_gp096;Dbxref=GeneID:72551512;Name=OPG117;gbkey=Gene;gene=OPG117;gene_biotype=protein_coding;locus_tag=NBT03_gp096;old_locus_tag=MPXV-M5312_HM12_Rivers-100 +NC_063383.1 RefSeq CDS 96049 98406 . + 0 ID=cds-YP_010377099.1;Parent=gene-NBT03_gp096;Dbxref=GenBank:YP_010377099.1,GeneID:72551512;Name=OPG117;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp102%3B nucleic acid-independent nucleoside triphosphatase%3B NTPase%2C DNA primase%3B similar to VACV-WR E5R and VACV-Cop D5R;gbkey=CDS;gene=OPG117;locus_tag=NBT03_gp096;product=NTPase (1);protein_id=YP_010377099.1 +NC_063383.1 RefSeq gene 98446 100359 . + . ID=gene-NBT03_gp097;Dbxref=GeneID:72551513;Name=OPG118;gbkey=Gene;gene=OPG118;gene_biotype=protein_coding;locus_tag=NBT03_gp097;old_locus_tag=MPXV-M5312_HM12_Rivers-101 +NC_063383.1 RefSeq CDS 98446 100359 . + 0 ID=cds-YP_010377100.1;Parent=gene-NBT03_gp097;Dbxref=GenBank:YP_010377100.1,GeneID:72551513;Name=OPG118;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp103%3B early transcription factor%2C small subunit%2C VETF-s%3B Morphogenesis%3B similar to VACV-WR E6R and VACV-Cop D6R;gbkey=CDS;gene=OPG118;locus_tag=NBT03_gp097;product=Early transcription factor 70 kDa subunit;protein_id=YP_010377100.1 +NC_063383.1 RefSeq gene 100386 100871 . + . ID=gene-NBT03_gp098;Dbxref=GeneID:72551514;Name=OPG119;gbkey=Gene;gene=OPG119;gene_biotype=protein_coding;locus_tag=NBT03_gp098;old_locus_tag=MPXV-M5312_HM12_Rivers-102 +NC_063383.1 RefSeq CDS 100386 100871 . + 0 ID=cds-YP_010377101.1;Parent=gene-NBT03_gp098;Dbxref=GenBank:YP_010377101.1,GeneID:72551514;Name=OPG119;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp104%3B RNA polymerase%2C 18 kDa subunit (RPO18)%3B similar to VACV-WR E7R and VACV-Cop D7R;gbkey=CDS;gene=OPG119;locus_tag=NBT03_gp098;product=RNA polymerase subunit RPO18;protein_id=YP_010377101.1 +NC_063383.1 RefSeq gene 100834 101748 . - . ID=gene-NBT03_gp099;Dbxref=GeneID:72551515;Name=OPG120;gbkey=Gene;gene=OPG120;gene_biotype=protein_coding;locus_tag=NBT03_gp099;old_locus_tag=MPXV-M5312_HM12_Rivers-103 +NC_063383.1 RefSeq CDS 100834 101748 . - 0 ID=cds-YP_010377102.1;Parent=gene-NBT03_gp099;Dbxref=GenBank:YP_010377102.1,GeneID:72551515;Name=OPG120;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp105%3B IMV surface membrane 32 kDa protein%3B binding to cell surface chondroitin sulfate%3B IMV adsorption to cell surface%3B GAG-binding IMV membrane protein%3B similar to VACV-WR E8L and VACV-Cop D8L;gbkey=CDS;gene=OPG120;locus_tag=NBT03_gp099;product=Carbonic anhydrase;protein_id=YP_010377102.1 +NC_063383.1 RefSeq gene 101790 102431 . + . ID=gene-NBT03_gp100;Dbxref=GeneID:72551516;Name=OPG121;gbkey=Gene;gene=OPG121;gene_biotype=protein_coding;locus_tag=NBT03_gp100;old_locus_tag=MPXV-M5312_HM12_Rivers-104 +NC_063383.1 RefSeq CDS 101790 102431 . + 0 ID=cds-YP_010377103.1;Parent=gene-NBT03_gp100;Dbxref=GenBank:YP_010377103.1,GeneID:72551516;Name=OPG121;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp106%3B Mut-like%3B mRNA decapping enzyme%3B similar to VACV-WR E9R and VACV-Cop D9R;gbkey=CDS;gene=OPG121;locus_tag=NBT03_gp100;product=NUDIX domain protein;protein_id=YP_010377103.1 +NC_063383.1 RefSeq gene 102428 103174 . + . ID=gene-NBT03_gp101;Dbxref=GeneID:72551517;Name=OPG122;gbkey=Gene;gene=OPG122;gene_biotype=protein_coding;locus_tag=NBT03_gp101;old_locus_tag=MPXV-M5312_HM12_Rivers-105 +NC_063383.1 RefSeq CDS 102428 103174 . + 0 ID=cds-YP_010377104.1;Parent=gene-NBT03_gp101;Dbxref=GenBank:YP_010377104.1,GeneID:72551517;Name=OPG122;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp107%3B down regulation of gene expression%3B Mut-like%3B mRNA decapping enzyme%3B similar to VACV-WR E10R and VACV-Cop D10R;gbkey=CDS;gene=OPG122;locus_tag=NBT03_gp101;product=MutT motif protein;protein_id=YP_010377104.1 +NC_063383.1 RefSeq gene 103175 105070 . - . ID=gene-NBT03_gp102;Dbxref=GeneID:72551518;Name=OPG123;gbkey=Gene;gene=OPG123;gene_biotype=protein_coding;locus_tag=NBT03_gp102;old_locus_tag=MPXV-M5312_HM12_Rivers-106 +NC_063383.1 RefSeq CDS 103175 105070 . - 0 ID=cds-YP_010377105.1;Parent=gene-NBT03_gp102;Dbxref=GenBank:YP_010377105.1,GeneID:72551518;Name=OPG123;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp108%3B nucleoside triphosphate phosphohydrolase I%2C NPH I%3B DNA-dependent ATPase%3B early gene transcription termination factor%3B similar to VACV-WR E11L and VACV-Cop D11L;gbkey=CDS;gene=OPG123;locus_tag=NBT03_gp102;product=Nucleoside triphosphatase I;protein_id=YP_010377105.1 +NC_063383.1 RefSeq gene 105105 105968 . - . ID=gene-NBT03_gp103;Dbxref=GeneID:72551519;Name=OPG124;gbkey=Gene;gene=OPG124;gene_biotype=protein_coding;locus_tag=NBT03_gp103;old_locus_tag=MPXV-M5312_HM12_Rivers-107 +NC_063383.1 RefSeq CDS 105105 105968 . - 0 ID=cds-YP_010377106.1;Parent=gene-NBT03_gp103;Dbxref=GenBank:YP_010377106.1,GeneID:72551519;Name=OPG124;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp109%3B mRNA capping enzyme small subunit%3B mRNA (guanine-N7-)-methyl-transferase%3B transcription initiation factor%3B similar to VACV-WR E12L and VACV-Cop D12L;gbkey=CDS;gene=OPG124;locus_tag=NBT03_gp103;product=mRNA capping enzyme small subunit;protein_id=YP_010377106.1 +NC_063383.1 RefSeq gene 105999 107654 . - . ID=gene-NBT03_gp104;Dbxref=GeneID:72551520;Name=OPG125;gbkey=Gene;gene=OPG125;gene_biotype=protein_coding;locus_tag=NBT03_gp104;old_locus_tag=MPXV-M5312_HM12_Rivers-108 +NC_063383.1 RefSeq CDS 105999 107654 . - 0 ID=cds-YP_010377107.1;Parent=gene-NBT03_gp104;Dbxref=GenBank:YP_010377107.1,GeneID:72551520;Name=OPG125;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp110%3B protein needed for the formation of immature IMV surface membrane%3B Trimeric virion coat protein (rifampicin res)%3B similar to VACV-WR E13L and VACV-Cop D13L;gbkey=CDS;gene=OPG125;locus_tag=NBT03_gp104;product=Rifampicin resistance protein;protein_id=YP_010377107.1 +NC_063383.1 RefSeq gene 107678 108130 . - . ID=gene-NBT03_gp105;Dbxref=GeneID:72551521;Name=OPG126;gbkey=Gene;gene=OPG126;gene_biotype=protein_coding;locus_tag=NBT03_gp105;old_locus_tag=MPXV-M5312_HM12_Rivers-109 +NC_063383.1 RefSeq CDS 107678 108130 . - 0 ID=cds-YP_010377108.1;Parent=gene-NBT03_gp105;Dbxref=GenBank:YP_010377108.1,GeneID:72551521;Name=OPG126;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp111%3B late gene transcription factor%2C VLTF-2%3B similar to VACV-WR A1L and VACV-Cop A1L;gbkey=CDS;gene=OPG126;locus_tag=NBT03_gp105;product=Late transcription factor VLTF-2 (2);protein_id=YP_010377108.1 +NC_063383.1 RefSeq gene 108151 108825 . - . ID=gene-NBT03_gp106;Dbxref=GeneID:72551522;Name=OPG127;gbkey=Gene;gene=OPG127;gene_biotype=protein_coding;locus_tag=NBT03_gp106;old_locus_tag=MPXV-M5312_HM12_Rivers-110 +NC_063383.1 RefSeq CDS 108151 108825 . - 0 ID=cds-YP_010377109.1;Parent=gene-NBT03_gp106;Dbxref=GenBank:YP_010377109.1,GeneID:72551522;Name=OPG127;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp112%3B late gene transcription factor%2C VLTF-3%3B zinc binding%3B similar to VACV-WR A2L and VACV-Cop A2L;gbkey=CDS;gene=OPG127;locus_tag=NBT03_gp106;product=Late transcription factor VLTF-3 (1);protein_id=YP_010377109.1 +NC_063383.1 RefSeq gene 108822 109055 . - . ID=gene-NBT03_gp107;Dbxref=GeneID:72551523;Name=OPG128;gbkey=Gene;gene=OPG128;gene_biotype=protein_coding;locus_tag=NBT03_gp107;old_locus_tag=MPXV-M5312_HM12_Rivers-111 +NC_063383.1 RefSeq CDS 108822 109055 . - 0 ID=cds-YP_010377110.1;Parent=gene-NBT03_gp107;Dbxref=GenBank:YP_010377110.1,GeneID:72551523;Name=OPG128;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp113%3B S-S bond formation pathway protein%3B similar to VACV-WR A3L and VACV-Cop A2.5L;gbkey=CDS;gene=OPG128;locus_tag=NBT03_gp107;product=S-S bond formation pathway protein;protein_id=YP_010377110.1 +NC_063383.1 RefSeq gene 109070 111004 . - . ID=gene-NBT03_gp108;Dbxref=GeneID:72551524;Name=OPG129;gbkey=Gene;gene=OPG129;gene_biotype=protein_coding;locus_tag=NBT03_gp108;old_locus_tag=MPXV-M5312_HM12_Rivers-112 +NC_063383.1 RefSeq CDS 109070 111004 . - 0 ID=cds-YP_010377111.1;Parent=gene-NBT03_gp108;Dbxref=GenBank:YP_010377111.1,GeneID:72551524;Name=OPG129;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp114%3B major virion core protein p4b%3B P4b precursor%3B similar to VACV-WR A4L and VACV-Cop A3L;gbkey=CDS;gene=OPG129;locus_tag=NBT03_gp108;product=Virion core protein P4b;protein_id=YP_010377111.1 +NC_063383.1 RefSeq gene 111057 111902 . - . ID=gene-NBT03_gp109;Dbxref=GeneID:72551525;Name=OPG130;gbkey=Gene;gene=OPG130;gene_biotype=protein_coding;locus_tag=NBT03_gp109;old_locus_tag=MPXV-M5312_HM12_Rivers-113 +NC_063383.1 RefSeq CDS 111057 111902 . - 0 ID=cds-YP_010377112.1;Parent=gene-NBT03_gp109;Dbxref=GenBank:YP_010377112.1,GeneID:72551525;Name=OPG130;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp115%3B 39 kDa immunodominant virion core protein needed for the progression of IV to infectious IMV%3B 39kDa virion core protein%3B similar to VACV-WR A5L and VACV-Cop A4L;gbkey=CDS;gene=OPG130;locus_tag=NBT03_gp109;product=A5L protein-like;protein_id=YP_010377112.1 +NC_063383.1 RefSeq gene 111940 112425 . + . ID=gene-NBT03_gp110;Dbxref=GeneID:72551526;Name=OPG131;gbkey=Gene;gene=OPG131;gene_biotype=protein_coding;locus_tag=NBT03_gp110;old_locus_tag=MPXV-M5312_HM12_Rivers-114 +NC_063383.1 RefSeq CDS 111940 112425 . + 0 ID=cds-YP_010377113.1;Parent=gene-NBT03_gp110;Dbxref=GenBank:YP_010377113.1,GeneID:72551526;Name=OPG131;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp116%3B precursor of RNA polymerase 22 kDa and 21 kDa%3B RNA polymerase subunit (RPO19)%3B similar to VACV-WR A6R and VACV-Cop A5R;gbkey=CDS;gene=OPG131;locus_tag=NBT03_gp110;product=DNA-directed RNA polymerase 19 kDa subunit;protein_id=YP_010377113.1 +NC_063383.1 RefSeq gene 112422 113540 . - . ID=gene-NBT03_gp111;Dbxref=GeneID:72551527;Name=OPG132;gbkey=Gene;gene=OPG132;gene_biotype=protein_coding;locus_tag=NBT03_gp111;old_locus_tag=MPXV-M5312_HM12_Rivers-115 +NC_063383.1 RefSeq CDS 112422 113540 . - 0 ID=cds-YP_010377114.1;Parent=gene-NBT03_gp111;Dbxref=GenBank:YP_010377114.1,GeneID:72551527;Name=OPG132;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp117%3B Viral membrane assembly proteins (VMAP)%2C core protein%3B similar to VACV-WR A7L and VACV-Cop A6L;gbkey=CDS;gene=OPG132;locus_tag=NBT03_gp111;product=Virion morphogenesis protein;protein_id=YP_010377114.1 +NC_063383.1 RefSeq gene 113564 115696 . - . ID=gene-NBT03_gp112;Dbxref=GeneID:72551528;Name=OPG133;gbkey=Gene;gene=OPG133;gene_biotype=protein_coding;locus_tag=NBT03_gp112;old_locus_tag=MPXV-M5312_HM12_Rivers-116 +NC_063383.1 RefSeq CDS 113564 115696 . - 0 ID=cds-YP_010377115.1;Parent=gene-NBT03_gp112;Dbxref=GenBank:YP_010377115.1,GeneID:72551528;Name=OPG133;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp118%3B early transcription factor%2C large subunit%2C VETF-L%3B needed for morphogenesis of the virion core%3B similar to VACV-WR A8L and VACV-Cop A7L;gbkey=CDS;gene=OPG133;locus_tag=NBT03_gp112;product=Early transcription factor 82 kDa subunit;protein_id=YP_010377115.1 +NC_063383.1 RefSeq gene 115750 116628 . + . ID=gene-NBT03_gp113;Dbxref=GeneID:72551529;Name=OPG134;gbkey=Gene;gene=OPG134;gene_biotype=protein_coding;locus_tag=NBT03_gp113;old_locus_tag=MPXV-M5312_HM12_Rivers-117 +NC_063383.1 RefSeq CDS 115750 116628 . + 0 ID=cds-YP_010377116.1;Parent=gene-NBT03_gp113;Dbxref=GenBank:YP_010377116.1,GeneID:72551529;Name=OPG134;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp119%3B intermediate transcription factor%2C VITF-3 34kda subunit%2C 34 kDa%3B similar to VACV-WR A9R and VACV-Cop A8R;gbkey=CDS;gene=OPG134;locus_tag=NBT03_gp113;product=Intermediate transcription factor VITF-3 (1);protein_id=YP_010377116.1 +NC_063383.1 RefSeq gene 116609 116911 . - . ID=gene-NBT03_gp114;Dbxref=GeneID:72551530;Name=OPG135;gbkey=Gene;gene=OPG135;gene_biotype=protein_coding;locus_tag=NBT03_gp114;old_locus_tag=MPXV-M5312_HM12_Rivers-118 +NC_063383.1 RefSeq CDS 116609 116911 . - 0 ID=cds-YP_010377117.1;Parent=gene-NBT03_gp114;Dbxref=GenBank:YP_010377117.1,GeneID:72551530;Name=OPG135;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp120%3B Viral membrane associated%2C early morphogenesis protein%3B similar to VACV-WR A10L and VACV-Cop A9L;gbkey=CDS;gene=OPG135;locus_tag=NBT03_gp114;product=IMV membrane protein A9;protein_id=YP_010377117.1 +NC_063383.1 RefSeq gene 116912 119587 . - . ID=gene-NBT03_gp115;Dbxref=GeneID:72551531;Name=OPG136;gbkey=Gene;gene=OPG136;gene_biotype=protein_coding;locus_tag=NBT03_gp115;old_locus_tag=MPXV-M5312_HM12_Rivers-119 +NC_063383.1 RefSeq CDS 116912 119587 . - 0 ID=cds-YP_010377118.1;Parent=gene-NBT03_gp115;Dbxref=GenBank:YP_010377118.1,GeneID:72551531;Name=OPG136;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp121%3B major virion core protein p4a%3B P4a precursor%3B similar to VACV-WR A11L and VACV-Cop A10L;gbkey=CDS;gene=OPG136;locus_tag=NBT03_gp115;product=Virion core protein P4a;protein_id=YP_010377118.1 +NC_063383.1 RefSeq gene 119602 120558 . + . ID=gene-NBT03_gp116;Dbxref=GeneID:72551532;Name=OPG137;gbkey=Gene;gene=OPG137;gene_biotype=protein_coding;locus_tag=NBT03_gp116;old_locus_tag=MPXV-M5312_HM12_Rivers-120 +NC_063383.1 RefSeq CDS 119602 120558 . + 0 ID=cds-YP_010377119.1;Parent=gene-NBT03_gp116;Dbxref=GenBank:YP_010377119.1,GeneID:72551532;Name=OPG137;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp122%3B Viral membrane assembly proteins (VMAP)%3B similar to VACV-WR A12R and VACV-Cop A11R;gbkey=CDS;gene=OPG137;locus_tag=NBT03_gp116;product=Viral membrane formation protein;protein_id=YP_010377119.1 +NC_063383.1 RefSeq gene 120560 121132 . - . ID=gene-NBT03_gp117;Dbxref=GeneID:72551533;Name=OPG138;gbkey=Gene;gene=OPG138;gene_biotype=protein_coding;locus_tag=NBT03_gp117;old_locus_tag=MPXV-M5312_HM12_Rivers-121 +NC_063383.1 RefSeq CDS 120560 121132 . - 0 ID=cds-YP_010377120.1;Parent=gene-NBT03_gp117;Dbxref=GenBank:YP_010377120.1,GeneID:72551533;Name=OPG138;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp123%3B Virion core and cleavage processing protein%3B similar to VACV-WR A13L and VACV-Cop A12L;gbkey=CDS;gene=OPG138;locus_tag=NBT03_gp117;product=A12 protein;protein_id=YP_010377120.1 +NC_063383.1 RefSeq gene 121156 121368 . - . ID=gene-NBT03_gp118;Dbxref=GeneID:72551534;Name=OPG139;gbkey=Gene;gene=OPG139;gene_biotype=protein_coding;locus_tag=NBT03_gp118;old_locus_tag=MPXV-M5312_HM12_Rivers-122 +NC_063383.1 RefSeq CDS 121156 121368 . - 0 ID=cds-YP_010377121.1;Parent=gene-NBT03_gp118;Dbxref=GenBank:YP_010377121.1,GeneID:72551534;Name=OPG139;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp124%3B IMV inner and outer membrane protein%3B virion maturation%3B similar to VACV-WR A14L and VACV-Cop A13L;gbkey=CDS;gene=OPG139;locus_tag=NBT03_gp118;product=IMV membrane protein A13L;protein_id=YP_010377121.1 +NC_063383.1 RefSeq gene 121474 121746 . - . ID=gene-NBT03_gp119;Dbxref=GeneID:72551535;Name=OPG140;gbkey=Gene;gene=OPG140;gene_biotype=protein_coding;locus_tag=NBT03_gp119;old_locus_tag=MPXV-M5312_HM12_Rivers-123 +NC_063383.1 RefSeq CDS 121474 121746 . - 0 ID=cds-YP_010377122.1;Parent=gene-NBT03_gp119;Dbxref=GenBank:YP_010377122.1,GeneID:72551535;Name=OPG140;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp125%3B IMV inner membrane protein%3B Essential IMV membrane protein%3B similar to VACV-WR A15L and VACV-Cop A14L;gbkey=CDS;gene=OPG140;locus_tag=NBT03_gp119;product=IMV membrane protein A14;protein_id=YP_010377122.1 +NC_063383.1 RefSeq gene 121763 121924 . - . ID=gene-NBT03_gp120;Dbxref=GeneID:72551536;Name=OPG141;gbkey=Gene;gene=OPG141;gene_biotype=protein_coding;locus_tag=NBT03_gp120;old_locus_tag=MPXV-M5312_HM12_Rivers-124 +NC_063383.1 RefSeq CDS 121763 121924 . - 0 ID=cds-YP_010377123.1;Parent=gene-NBT03_gp120;Dbxref=GenBank:YP_010377123.1,GeneID:72551536;Name=OPG141;Note=Taxonomic breadth: chordopoxvirinae%3B Non-essential IMV membrane protein%3B similar to VACV-WR A15.5L and VACV-Cop A14.5L;gbkey=CDS;gene=OPG141;locus_tag=NBT03_gp120;product=DUF1029 domain protein;protein_id=YP_010377123.1 +NC_063383.1 RefSeq gene 121914 122198 . - . ID=gene-NBT03_gp121;Dbxref=GeneID:72551537;Name=OPG142;gbkey=Gene;gene=OPG142;gene_biotype=protein_coding;locus_tag=NBT03_gp121;old_locus_tag=MPXV-M5312_HM12_Rivers-125 +NC_063383.1 RefSeq CDS 121914 122198 . - 0 ID=cds-YP_010377124.1;Parent=gene-NBT03_gp121;Dbxref=GenBank:YP_010377124.1,GeneID:72551537;Name=OPG142;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp126%3B Core protein%3B similar to VACV-WR A16L and VACV-Cop A15L;gbkey=CDS;gene=OPG142;locus_tag=NBT03_gp121;product=Core protein A15;protein_id=YP_010377124.1 +NC_063383.1 RefSeq gene 122182 123315 . - . ID=gene-NBT03_gp122;Dbxref=GeneID:72551538;Name=OPG143;gbkey=Gene;gene=OPG143;gene_biotype=protein_coding;locus_tag=NBT03_gp122;old_locus_tag=MPXV-M5312_HM12_Rivers-126 +NC_063383.1 RefSeq CDS 122182 123315 . - 0 ID=cds-YP_010377125.1;Parent=gene-NBT03_gp122;Dbxref=GenBank:YP_010377125.1,GeneID:72551538;Name=OPG143;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp127%3B soluble myristylated protein%3B essential for entry/fusion%3B similar to VACV-WR A17L and VACV-Cop A16L;gbkey=CDS;gene=OPG143;locus_tag=NBT03_gp122;product=Myristylated protein;protein_id=YP_010377125.1 +NC_063383.1 RefSeq gene 123318 123932 . - . ID=gene-NBT03_gp123;Dbxref=GeneID:72551539;Name=OPG144;gbkey=Gene;gene=OPG144;gene_biotype=protein_coding;locus_tag=NBT03_gp123;old_locus_tag=MPXV-M5312_HM12_Rivers-127 +NC_063383.1 RefSeq CDS 123318 123932 . - 0 ID=cds-YP_010377126.1;Parent=gene-NBT03_gp123;Dbxref=GenBank:YP_010377126.1,GeneID:72551539;Name=OPG144;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp128%3B IMV surface membrane protein%3B early function in virion morphgenesis%3B similar to VACV-WR A18L and VACV-Cop A17L;gbkey=CDS;gene=OPG144;locus_tag=NBT03_gp123;product=IMV membrane protein P21;protein_id=YP_010377126.1 +NC_063383.1 RefSeq gene 123947 125425 . + . ID=gene-NBT03_gp124;Dbxref=GeneID:72551540;Name=OPG145;gbkey=Gene;gene=OPG145;gene_biotype=protein_coding;locus_tag=NBT03_gp124;old_locus_tag=MPXV-M5312_HM12_Rivers-128 +NC_063383.1 RefSeq CDS 123947 125425 . + 0 ID=cds-YP_010377127.1;Parent=gene-NBT03_gp124;Dbxref=GenBank:YP_010377127.1,GeneID:72551540;Name=OPG145;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp129%3B virion core associated DNA helicase%3B post-replicative negative transcription elongation factor%3B transcript release factor%3B similar to VACV-WR A19R and VACV-Cop A18R;gbkey=CDS;gene=OPG145;locus_tag=NBT03_gp124;product=DNA helicase;protein_id=YP_010377127.1 +NC_063383.1 RefSeq gene 125406 125639 . - . ID=gene-NBT03_gp125;Dbxref=GeneID:72551541;Name=OPG146;gbkey=Gene;gene=OPG146;gene_biotype=protein_coding;locus_tag=NBT03_gp125;old_locus_tag=MPXV-M5312_HM12_Rivers-129 +NC_063383.1 RefSeq CDS 125406 125639 . - 0 ID=cds-YP_010377128.1;Parent=gene-NBT03_gp125;Dbxref=GenBank:YP_010377128.1,GeneID:72551541;Name=OPG146;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp130%3B Zinc finger-like protein%3B similar to VACV-WR A20L and VACV-Cop A19L;gbkey=CDS;gene=OPG146;locus_tag=NBT03_gp125;product=Zinc finger-like protein (1);protein_id=YP_010377128.1 +NC_063383.1 RefSeq gene 125640 125987 . - . ID=gene-NBT03_gp126;Dbxref=GeneID:72551542;Name=OPG147;gbkey=Gene;gene=OPG147;gene_biotype=protein_coding;locus_tag=NBT03_gp126;old_locus_tag=MPXV-M5312_HM12_Rivers-130 +NC_063383.1 RefSeq CDS 125640 125987 . - 0 ID=cds-YP_010377129.1;Parent=gene-NBT03_gp126;Dbxref=GenBank:YP_010377129.1,GeneID:72551542;Name=OPG147;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp131%3B IMV membrane protein%2C entry/fusion complex component%3B similar to VACV-WR A21L and VACV-Cop A21L;gbkey=CDS;gene=OPG147;locus_tag=NBT03_gp126;product=IMV membrane protein A21;protein_id=YP_010377129.1 +NC_063383.1 RefSeq gene 125986 127266 . + . ID=gene-NBT03_gp127;Dbxref=GeneID:72551543;Name=OPG148;gbkey=Gene;gene=OPG148;gene_biotype=protein_coding;locus_tag=NBT03_gp127;old_locus_tag=MPXV-M5312_HM12_Rivers-131 +NC_063383.1 RefSeq CDS 125986 127266 . + 0 ID=cds-YP_010377130.1;Parent=gene-NBT03_gp127;Dbxref=GenBank:YP_010377130.1,GeneID:72551543;Name=OPG148;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp132%3B processivity factor for the viral DNA polymerase%2C VPF%3B similar to VACV-WR A22R and VACV-Cop A20R;gbkey=CDS;gene=OPG148;locus_tag=NBT03_gp127;product=DNA polymerase processivity factor;protein_id=YP_010377130.1 +NC_063383.1 RefSeq gene 127196 127759 . + . ID=gene-NBT03_gp128;Dbxref=GeneID:72551544;Name=OPG149;gbkey=Gene;gene=OPG149;gene_biotype=protein_coding;locus_tag=NBT03_gp128;old_locus_tag=MPXV-M5312_HM12_Rivers-132 +NC_063383.1 RefSeq CDS 127196 127759 . + 0 ID=cds-YP_010377131.1;Parent=gene-NBT03_gp128;Dbxref=GenBank:YP_010377131.1,GeneID:72551544;Name=OPG149;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp133%3B Holliday junction resolvase%3B similar to VACV-WR A23R and VACV-Cop A22R;gbkey=CDS;gene=OPG149;locus_tag=NBT03_gp128;product=Holliday junction resolvase;protein_id=YP_010377131.1 +NC_063383.1 RefSeq gene 127779 128927 . + . ID=gene-NBT03_gp129;Dbxref=GeneID:72551545;Name=OPG150;gbkey=Gene;gene=OPG150;gene_biotype=protein_coding;locus_tag=NBT03_gp129;old_locus_tag=MPXV-M5312_HM12_Rivers-133 +NC_063383.1 RefSeq CDS 127779 128927 . + 0 ID=cds-YP_010377132.1;Parent=gene-NBT03_gp129;Dbxref=GenBank:YP_010377132.1,GeneID:72551545;Name=OPG150;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp134%3B intermediate transcription factor%2C VITF-3%2C 45 kDa subunit%3B similar to VACV-WR A24R and VACV-Cop A23R;gbkey=CDS;gene=OPG150;locus_tag=NBT03_gp129;product=Intermediate transcription factor VITF-3 (2);protein_id=YP_010377132.1 +NC_063383.1 RefSeq gene 128924 132418 . + . ID=gene-NBT03_gp130;Dbxref=GeneID:72551546;Name=OPG151;gbkey=Gene;gene=OPG151;gene_biotype=protein_coding;locus_tag=NBT03_gp130;old_locus_tag=MPXV-M5312_HM12_Rivers-134 +NC_063383.1 RefSeq CDS 128924 132418 . + 0 ID=cds-YP_010377133.1;Parent=gene-NBT03_gp130;Dbxref=GenBank:YP_010377133.1,GeneID:72551546;Name=OPG151;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp135%3B RNA polymerase%2C 132 kDa subunit (RPO132)%3B similar to VACV-WR A25R and VACV-Cop A24R;gbkey=CDS;gene=OPG151;locus_tag=NBT03_gp130;product=DNA-dependent RNA polymerase subunit rpo132;protein_id=YP_010377133.1 +NC_063383.1 RefSeq sequence_feature 132396 136092 . - . ID=id-NC_063383.1:132396..136092;exon_number=OPG152;gbkey=misc_feature;number=OPG152 +NC_063383.1 RefSeq gene 136138 137667 . - . ID=gene-NBT03_gp131;Dbxref=GeneID:72551547;Name=OPG153;gbkey=Gene;gene=OPG153;gene_biotype=protein_coding;locus_tag=NBT03_gp131;old_locus_tag=MPXV-M5312_HM12_Rivers-137 +NC_063383.1 RefSeq CDS 136138 137667 . - 0 ID=cds-YP_010377134.1;Parent=gene-NBT03_gp131;Dbxref=GenBank:YP_010377134.1,GeneID:72551547;Name=OPG153;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp138%3B major component of IMV surface tubules%3B A-type inclusion protein%3B P4c precursor%3B similar to VACV-WR A28L and VACV-Cop A26L;gbkey=CDS;gene=OPG153;locus_tag=NBT03_gp131;product=Orthopoxvirus A26L/A30L protein;protein_id=YP_010377134.1 +NC_063383.1 RefSeq gene 137718 138050 . - . ID=gene-NBT03_gp132;Dbxref=GeneID:72551548;Name=OPG154;gbkey=Gene;gene=OPG154;gene_biotype=protein_coding;locus_tag=NBT03_gp132;old_locus_tag=MPXV-M5312_HM12_Rivers-138 +NC_063383.1 RefSeq CDS 137718 138050 . - 0 ID=cds-YP_010377135.1;Parent=gene-NBT03_gp132;Dbxref=GenBank:YP_010377135.1,GeneID:72551548;Name=OPG154;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp139%3B IMV surface membrane 14 kDa fusion protein%3B binding to cell surface heparan%3B similar to VACV-WR A29L and VACV-Cop A27L;gbkey=CDS;gene=OPG154;locus_tag=NBT03_gp132;product=IMV surface fusion protein;protein_id=YP_010377135.1 +NC_063383.1 RefSeq gene 138051 138491 . - . ID=gene-NBT03_gp133;Dbxref=GeneID:72551549;Name=OPG155;gbkey=Gene;gene=OPG155;gene_biotype=protein_coding;locus_tag=NBT03_gp133;old_locus_tag=MPXV-M5312_HM12_Rivers-139 +NC_063383.1 RefSeq CDS 138051 138491 . - 0 ID=cds-YP_010377136.1;Parent=gene-NBT03_gp133;Dbxref=GenBank:YP_010377136.1,GeneID:72551549;Name=OPG155;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp140%3B IMV MP/Virus entry%3B similar to VACV-WR A30L and VACV-Cop A28L;gbkey=CDS;gene=OPG155;locus_tag=NBT03_gp133;product=Envelope protein A28 homolog;protein_id=YP_010377136.1 +NC_063383.1 RefSeq gene 138492 139409 . - . ID=gene-NBT03_gp134;Dbxref=GeneID:72551550;Name=OPG156;gbkey=Gene;gene=OPG156;gene_biotype=protein_coding;locus_tag=NBT03_gp134;old_locus_tag=MPXV-M5312_HM12_Rivers-140 +NC_063383.1 RefSeq CDS 138492 139409 . - 0 ID=cds-YP_010377137.1;Parent=gene-NBT03_gp134;Dbxref=GenBank:YP_010377137.1,GeneID:72551550;Name=OPG156;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp141%3B RNA polymerase%2C 35 kDa subunit (RPO35)%3B similar to VACV-WR A31L and VACV-Cop A29L;gbkey=CDS;gene=OPG156;locus_tag=NBT03_gp134;product=DNA-directed RNA polymerase 35 kDa subunit;protein_id=YP_010377137.1 +NC_063383.1 RefSeq gene 139372 139608 . - . ID=gene-NBT03_gp135;Dbxref=GeneID:72551551;Name=OPG157;gbkey=Gene;gene=OPG157;gene_biotype=protein_coding;locus_tag=NBT03_gp135;old_locus_tag=MPXV-M5312_HM12_Rivers-141 +NC_063383.1 RefSeq CDS 139372 139608 . - 0 ID=cds-YP_010377138.1;Parent=gene-NBT03_gp135;Dbxref=GenBank:YP_010377138.1,GeneID:72551551;Name=OPG157;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp142%3B IMV protein%3B similar to VACV-WR A32L and VACV-Cop A30L;gbkey=CDS;gene=OPG157;locus_tag=NBT03_gp135;product=IMV membrane protein A30;protein_id=YP_010377138.1 +NC_063383.1 RefSeq gene 139641 139769 . - . ID=gene-NBT03_gp136;Dbxref=GeneID:72551552;Name=OPG158;gbkey=Gene;gene=OPG158;gene_biotype=protein_coding;locus_tag=NBT03_gp136;old_locus_tag=MPXV-M5312_HM12_Rivers-142 +NC_063383.1 RefSeq CDS 139641 139769 . - 0 ID=cds-YP_010377139.1;Parent=gene-NBT03_gp136;Dbxref=GenBank:YP_010377139.1,GeneID:72551552;Name=OPG158;Note=Viral membrane assembly proteins (VMAP)%3B similar to VACV-Cop A30.5L;gbkey=CDS;gene=OPG158;locus_tag=NBT03_gp136;product=A32.5L;protein_id=YP_010377139.1 +NC_063383.1 RefSeq gene 139768 140205 . + . ID=gene-NBT03_gp137;Dbxref=GeneID:72551553;Name=OPG159;gbkey=Gene;gene=OPG159;gene_biotype=protein_coding;locus_tag=NBT03_gp137;old_locus_tag=MPXV-M5312_HM12_Rivers-143 +NC_063383.1 RefSeq CDS 139768 140205 . + 0 ID=cds-YP_010377140.1;Parent=gene-NBT03_gp137;Dbxref=GenBank:YP_010377140.1,GeneID:72551553;Name=OPG159;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp143%3B Hypothetical protein%3B similar to VACV-WR A33R and VACV-Cop A31R;gbkey=CDS;gene=OPG159;locus_tag=NBT03_gp137;product=CPXV166 protein;protein_id=YP_010377140.1 +NC_063383.1 RefSeq gene 140172 141074 . - . ID=gene-NBT03_gp138;Dbxref=GeneID:72551554;Name=OPG160;gbkey=Gene;gene=OPG160;gene_biotype=protein_coding;locus_tag=NBT03_gp138;old_locus_tag=MPXV-M5312_HM12_Rivers-144 +NC_063383.1 RefSeq CDS 140172 141074 . - 0 ID=cds-YP_010377141.1;Parent=gene-NBT03_gp138;Dbxref=GenBank:YP_010377141.1,GeneID:72551554;Name=OPG160;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp144%3B DNA packaging into virion%3B NTP-binding motif A%3B ATPase/DNA packaging protein%3B similar to VACV-WR A34L and VACV-Cop A32L;gbkey=CDS;gene=OPG160;locus_tag=NBT03_gp138;product=ATPase A32;protein_id=YP_010377141.1 +NC_063383.1 RefSeq gene 141102 141647 . + . ID=gene-NBT03_gp139;Dbxref=GeneID:72551555;Name=OPG161;gbkey=Gene;gene=OPG161;gene_biotype=protein_coding;locus_tag=NBT03_gp139;old_locus_tag=MPXV-M5312_HM12_Rivers-145 +NC_063383.1 RefSeq CDS 141102 141647 . + 0 ID=cds-YP_010377142.1;Parent=gene-NBT03_gp139;Dbxref=GenBank:YP_010377142.1,GeneID:72551555;Name=OPG161;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp145%3B EEV envelope glycoprotein%2C needed for formation of actin-containing microvilli and cell-to-cell spread of virion%3B interacts with VAC A36R%3B EEV membrane phosphoglycoprotein%2C C-type lectin-like domain%3B similar to VACV-WR A35R and VACV-Cop A33R;gbkey=CDS;gene=OPG161;locus_tag=NBT03_gp139;product=EEV glycoprotein (1);protein_id=YP_010377142.1 +NC_063383.1 RefSeq gene 141652 142158 . + . ID=gene-NBT03_gp140;Dbxref=GeneID:72551556;Name=OPG162;gbkey=Gene;gene=OPG162;gene_biotype=protein_coding;locus_tag=NBT03_gp140;old_locus_tag=MPXV-M5312_HM12_Rivers-146 +NC_063383.1 RefSeq CDS 141652 142158 . + 0 ID=cds-YP_010377143.1;Parent=gene-NBT03_gp140;Dbxref=GenBank:YP_010377143.1,GeneID:72551556;Name=OPG162;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp146%3B EEV envelope glycoprotein%2C lectin-like%3B required for infectivity of EEV%2C formation of actin-containing microvilli%2C and cell-to-cell spread of virion%3B C-type lectin-like IEV/EEV glycoprotein%3B similar to VACV-WR A36R and VACV-Cop A34R;gbkey=CDS;gene=OPG162;locus_tag=NBT03_gp140;product=EEV glycoprotein (2);protein_id=YP_010377143.1 +NC_063383.1 RefSeq gene 142202 142732 . + . ID=gene-NBT03_gp141;Dbxref=GeneID:72551557;Name=OPG163;gbkey=Gene;gene=OPG163;gene_biotype=protein_coding;locus_tag=NBT03_gp141;old_locus_tag=MPXV-M5312_HM12_Rivers-147 +NC_063383.1 RefSeq CDS 142202 142732 . + 0 ID=cds-YP_010377144.1;Parent=gene-NBT03_gp141;Dbxref=GenBank:YP_010377144.1,GeneID:72551557;Name=OPG163;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp147%3B MHC class II antigen presentation inhibitor%3B similar to VACV-WR A37R and VACV-Cop A35R;gbkey=CDS;gene=OPG163;locus_tag=NBT03_gp141;product=MHC class II antigen presentation inhibitor;protein_id=YP_010377144.1 +NC_063383.1 RefSeq gene 142778 143464 . + . ID=gene-NBT03_gp142;Dbxref=GeneID:72551558;Name=OPG164;gbkey=Gene;gene=OPG164;gene_biotype=protein_coding;locus_tag=NBT03_gp142;old_locus_tag=MPXV-M5312_HM12_Rivers-148 +NC_063383.1 RefSeq CDS 142778 143464 . + 0 ID=cds-YP_010377145.1;Parent=gene-NBT03_gp142;Dbxref=GenBank:YP_010377145.1,GeneID:72551558;Name=OPG164;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp148%3B IEV but not CEV envelope protein%3B plays critical role for actin tail formation%3B interacts with VAC A33R and A34R%3B IEV transmembrane phosphoprotein%3B similar to VACV-WR A38R and VACV-Cop A36R;gbkey=CDS;gene=OPG164;locus_tag=NBT03_gp142;product=IEV transmembrane phosphoprotein;protein_id=YP_010377145.1 +NC_063383.1 RefSeq gene 143516 144322 . + . ID=gene-NBT03_gp143;Dbxref=GeneID:72551559;Name=OPG165;gbkey=Gene;gene=OPG165;gene_biotype=protein_coding;locus_tag=NBT03_gp143;old_locus_tag=MPXV-M5312_HM12_Rivers-149 +NC_063383.1 RefSeq CDS 143516 144322 . + 0 ID=cds-YP_010377146.1;Parent=gene-NBT03_gp143;Dbxref=GenBank:YP_010377146.1,GeneID:72551559;Name=OPG165;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp149%3B Hypothetical protein%3B similar to VACV-WR A39R and VACV-Cop A37R;gbkey=CDS;gene=OPG165;locus_tag=NBT03_gp143;product=CPXV173 protein;protein_id=YP_010377146.1 +NC_063383.1 RefSeq gene 144398 144577 . + . ID=gene-NBT03_gp144;Dbxref=GeneID:72551560;Name=OPG166;gbkey=Gene;gene=OPG166;gene_biotype=protein_coding;locus_tag=NBT03_gp144 +NC_063383.1 RefSeq CDS 144398 144577 . + 0 ID=cds-YP_010415322.1;Parent=gene-NBT03_gp144;Dbxref=GenBank:YP_010415322.1,GeneID:72551560;Name=OPG166;Note=Hypothetical protein%3B according to YP_233043.1%2C this VACV-WR protein was purified by sucrose gradient centrifugation%3B similar to VACWR161 and VARGAR-A43R;gbkey=CDS;gene=OPG166;locus_tag=NBT03_gp144;product=hypothetical protein;protein_id=YP_010415322.1 +NC_063383.1 RefSeq gene 144574 145407 . - . ID=gene-NBT03_gp145;Dbxref=GeneID:72551561;Name=OPG167;gbkey=Gene;gene=OPG167;gene_biotype=protein_coding;locus_tag=NBT03_gp145;old_locus_tag=MPXV-M5312_HM12_Rivers-150 +NC_063383.1 RefSeq CDS 144574 145407 . - 0 ID=cds-YP_010377147.1;Parent=gene-NBT03_gp145;Dbxref=GenBank:YP_010377147.1,GeneID:72551561;Name=OPG167;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp150%3B integral membrane glycoprotein%3B immunoglobulin-like%3B regulation of the influx of extracellular Ca2+%3B CD47-like%3B similar to VACV-WR A40L and VACV-Cop A38L;gbkey=CDS;gene=OPG167;locus_tag=NBT03_gp145;product=CD47-like protein;protein_id=YP_010377147.1 +NC_063383.1 RefSeq sequence_feature 145423 145856 . + . ID=id-NC_063383.1:145423..145856;exon_number=OPG168;gbkey=misc_feature;number=OPG168 +NC_063383.1 RefSeq sequence_feature 145857 146039 . + . ID=id-NC_063383.1:145857..146039;exon_number=OPG169;gbkey=misc_feature;number=OPG169 +NC_063383.1 RefSeq gene 146113 146778 . - . ID=gene-NBT03_gp146;Dbxref=GeneID:72551562;Name=OPG170;gbkey=Gene;gene=OPG170;gene_biotype=protein_coding;locus_tag=NBT03_gp146;old_locus_tag=MPXV-M5312_HM12_Rivers-151 +NC_063383.1 RefSeq CDS 146113 146778 . - 0 ID=cds-YP_010377148.1;Parent=gene-NBT03_gp146;Dbxref=GenBank:YP_010377148.1,GeneID:72551562;Name=OPG170;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp151%3B secreted protein reducing infiltration of inflammatory cells into the infected area%3B Chemokine binding protein%3B similar to VACV-WR A41L and VACV-Cop A41L;gbkey=CDS;gene=OPG170;locus_tag=NBT03_gp146;product=Chemokine binding protein;protein_id=YP_010377148.1 +NC_063383.1 RefSeq gene 146988 147389 . + . ID=gene-NBT03_gp147;Dbxref=GeneID:72551563;Name=OPG171;gbkey=Gene;gene=OPG171;gene_biotype=protein_coding;locus_tag=NBT03_gp147;old_locus_tag=MPXV-M5312_HM12_Rivers-152 +NC_063383.1 RefSeq CDS 146988 147389 . + 0 ID=cds-YP_010377149.1;Parent=gene-NBT03_gp147;Dbxref=GenBank:YP_010377149.1,GeneID:72551563;Name=OPG171;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp152%3B Profilin-like protein%2C ATI-localized%3B similar to VACV-WR A42R and VACV-Cop A42R;gbkey=CDS;gene=OPG171;locus_tag=NBT03_gp147;product=Profilin domain protein;protein_id=YP_010377149.1 +NC_063383.1 RefSeq gene 147427 148017 . + . ID=gene-NBT03_gp148;Dbxref=GeneID:72551564;Name=OPG172;gbkey=Gene;gene=OPG172;gene_biotype=protein_coding;locus_tag=NBT03_gp148;old_locus_tag=MPXV-M5312_HM12_Rivers-153 +NC_063383.1 RefSeq CDS 147427 148017 . + 0 ID=cds-YP_010377150.1;Parent=gene-NBT03_gp148;Dbxref=GenBank:YP_010377150.1,GeneID:72551564;Name=OPG172;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp153%3B Type I membrane glycoprotein%3B similar to VACV-WR A43R and VACV-Cop A43R;gbkey=CDS;gene=OPG172;locus_tag=NBT03_gp148;product=Type-I membrane glycoprotein;protein_id=YP_010377150.1 +NC_063383.1 RefSeq gene 148037 148261 . + . ID=gene-NBT03_gp149;Dbxref=GeneID:72551565;Name=OPG173;gbkey=Gene;gene=OPG173;gene_biotype=protein_coding;locus_tag=NBT03_gp149;old_locus_tag=MPXV-M5312_HM12_Rivers-154 +NC_063383.1 RefSeq CDS 148037 148261 . + 0 ID=cds-YP_010377151.1;Parent=gene-NBT03_gp149;Dbxref=GenBank:YP_010377151.1,GeneID:72551565;Name=OPG173;Note=Old product: MPXVgp154%3B Hypothetical protein%3B similar to VACV-WR A44R and VACV-Cop A43.5R;gbkey=CDS;gene=OPG173;locus_tag=NBT03_gp149;product=MPXVgp154;protein_id=YP_010377151.1 +NC_063383.1 RefSeq gene 148355 149395 . - . ID=gene-NBT03_gp150;Dbxref=GeneID:72551566;Name=OPG174;gbkey=Gene;gene=OPG174;gene_biotype=protein_coding;locus_tag=NBT03_gp150;old_locus_tag=MPXV-M5312_HM12_Rivers-155 +NC_063383.1 RefSeq CDS 148355 149395 . - 0 ID=cds-YP_010377152.1;Parent=gene-NBT03_gp150;Dbxref=GenBank:YP_010377152.1,GeneID:72551566;Name=OPG174;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp155%3B 3-b-Hydroxy-delta5-steroid dehydrogenase%3B 3 beta-hydroxysteroid dehydrogenase/delta 5->4 isomerase%3B similar to VACV-WR A45L and VACV-Cop A44L;gbkey=CDS;gene=OPG174;locus_tag=NBT03_gp150;product=Hydroxysteroid dehydrogenase;protein_id=YP_010377152.1 +NC_063383.1 RefSeq gene 149442 149819 . + . ID=gene-NBT03_gp151;Dbxref=GeneID:72551567;Name=OPG175;gbkey=Gene;gene=OPG175;gene_biotype=protein_coding;locus_tag=NBT03_gp151;old_locus_tag=MPXV-M5312_HM12_Rivers-156 +NC_063383.1 RefSeq CDS 149442 149819 . + 0 ID=cds-YP_010377153.1;Parent=gene-NBT03_gp151;Dbxref=GenBank:YP_010377153.1,GeneID:72551567;Name=OPG175;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp156%3B virion core protein%3B Inactive Cu-Zn superoxide dismutase-like virion protein%3B similar to VACV-WR A46R and VACV-Cop A45R;gbkey=CDS;gene=OPG175;locus_tag=NBT03_gp151;product=Copper/zinc superoxide dismutase;protein_id=YP_010377153.1 +NC_063383.1 RefSeq gene 149809 150531 . + . ID=gene-NBT03_gp152;Dbxref=GeneID:72551568;Name=OPG176;gbkey=Gene;gene=OPG176;gene_biotype=protein_coding;locus_tag=NBT03_gp152;old_locus_tag=MPXV-M5312_HM12_Rivers-157 +NC_063383.1 RefSeq CDS 149809 150531 . + 0 ID=cds-YP_010377154.1;Parent=gene-NBT03_gp152;Dbxref=GenBank:YP_010377154.1,GeneID:72551568;Name=OPG176;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp157%3B IL-1/TLR signaling inhibitor%3B similar to VACV-WR A47R and VACV-Cop A46R;gbkey=CDS;gene=OPG176;locus_tag=NBT03_gp152;product=Bcl-2-like protein;protein_id=YP_010377154.1 +NC_063383.1 RefSeq sequence_feature 150684 151407 . - . ID=id-NC_063383.1:150684..151407;exon_number=OPG177;gbkey=misc_feature;number=OPG177 +NC_063383.1 RefSeq gene 151509 152123 . + . ID=gene-NBT03_gp153;Dbxref=GeneID:72551569;Name=OPG178;gbkey=Gene;gene=OPG178;gene_biotype=protein_coding;locus_tag=NBT03_gp153;old_locus_tag=MPXV-M5312_HM12_Rivers-158 +NC_063383.1 RefSeq CDS 151509 152123 . + 0 ID=cds-YP_010377155.1;Parent=gene-NBT03_gp153;Dbxref=GenBank:YP_010377155.1,GeneID:72551569;Name=OPG178;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp159%3B thymidylate kinase%3B start of ORF is missing approx. 37 AA compared to CPXVs%3B similar to VACV-WR A49R and VACV-Cop A48R;gbkey=CDS;gene=OPG178;locus_tag=NBT03_gp153;product=Thymidylate kinase;protein_id=YP_010377155.1 +NC_063383.1 RefSeq sequence_feature 152172 152660 . + . ID=id-NC_063383.1:152172..152660;exon_number=OPG179;gbkey=misc_feature;number=OPG179 +NC_063383.1 RefSeq gene 152692 154371 . + . ID=gene-NBT03_gp154;Dbxref=GeneID:72551570;Name=OPG180;gbkey=Gene;gene=OPG180;gene_biotype=protein_coding;locus_tag=NBT03_gp154;old_locus_tag=MPXV-M5312_HM12_Rivers-159 +NC_063383.1 RefSeq CDS 152692 154371 . + 0 ID=cds-YP_010377156.1;Parent=gene-NBT03_gp154;Dbxref=GenBank:YP_010377156.1,GeneID:72551570;Name=OPG180;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp160%3B ATP-dependent DNA ligase%3B similar to VACV-WR A50R and VACV-Cop A50R;gbkey=CDS;gene=OPG180;locus_tag=NBT03_gp154;product=DNA ligase (2);protein_id=YP_010377156.1 +NC_063383.1 RefSeq gene 154412 155416 . + . ID=gene-NBT03_gp155;Dbxref=GeneID:72551571;Name=OPG181;gbkey=Gene;gene=OPG181;gene_biotype=protein_coding;locus_tag=NBT03_gp155;old_locus_tag=MPXV-M5312_HM12_Rivers-160 +NC_063383.1 RefSeq CDS 154412 155416 . + 0 ID=cds-YP_010377157.1;Parent=gene-NBT03_gp155;Dbxref=GenBank:YP_010377157.1,GeneID:72551571;Name=OPG181;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp161%3B Hypothetical protein%3B similar to VACV-WR A51R and VACV-Cop A51R;gbkey=CDS;gene=OPG181;locus_tag=NBT03_gp155;product=M137R;protein_id=YP_010377157.1 +NC_063383.1 RefSeq sequence_feature 155485 156037 . + . ID=id-NC_063383.1:155485..156037;exon_number=OPG182;gbkey=misc_feature;number=OPG182 +NC_063383.1 RefSeq sequence_feature 156355 156916 . + . ID=id-NC_063383.1:156355..156916;exon_number=OPG183;gbkey=misc_feature;number=OPG183 +NC_063383.1 RefSeq sequence_feature 157176 158867 . + . ID=id-NC_063383.1:157176..158867;exon_number=OPG184;gbkey=misc_feature;number=OPG184 +NC_063383.1 RefSeq gene 158917 159858 . + . ID=gene-NBT03_gp156;Dbxref=GeneID:72551572;Name=OPG185;gbkey=Gene;gene=OPG185;gene_biotype=protein_coding;locus_tag=NBT03_gp156;old_locus_tag=MPXV-M5312_HM12_Rivers-162 +NC_063383.1 RefSeq CDS 158917 159858 . + 0 ID=cds-YP_010377158.1;Parent=gene-NBT03_gp156;Dbxref=GenBank:YP_010377158.1,GeneID:72551572;Name=OPG185;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp163%3B EEV envelope and cell membrane glycoprotein hemagglutinin%3B inhibition of the ability of infected cells to fuse%3B interacts with VAC F13L%3B similar to VACV-WR B2R and VACV-Cop A56R;gbkey=CDS;gene=OPG185;locus_tag=NBT03_gp156;product=Hemagglutinin;protein_id=YP_010377158.1 +NC_063383.1 RefSeq sequence_feature 159876 160470 . + . ID=id-NC_063383.1:159876..160470;exon_number=OPG186;gbkey=misc_feature;number=OPG186 +NC_063383.1 RefSeq gene 160622 161533 . + . ID=gene-NBT03_gp157;Dbxref=GeneID:72551573;Name=OPG187;gbkey=Gene;gene=OPG187;gene_biotype=protein_coding;locus_tag=NBT03_gp157;old_locus_tag=MPXV-M5312_HM12_Rivers-163 +NC_063383.1 RefSeq CDS 160622 161533 . + 0 ID=cds-YP_010377159.1;Parent=gene-NBT03_gp157;Dbxref=GenBank:YP_010377159.1,GeneID:72551573;Name=OPG187;Note=Taxonomic breadth: poxviridae%3B Old product: MPXVgp164%3B serine%3B Ser/Thr Kinase%3B similar to VACV-WR B3R and VACV-Cop B1R;gbkey=CDS;gene=OPG187;locus_tag=NBT03_gp157;product=Ser/thr kinase;protein_id=YP_010377159.1 +NC_063383.1 RefSeq gene 161596 163107 . + . ID=gene-NBT03_gp158;Dbxref=GeneID:72551574;Name=OPG188;gbkey=Gene;gene=OPG188;gene_biotype=protein_coding;locus_tag=NBT03_gp158;old_locus_tag=MPXV-M5312_HM12_Rivers-164 +NC_063383.1 RefSeq CDS 161596 163107 . + 0 ID=cds-YP_010377160.1;Parent=gene-NBT03_gp158;Dbxref=GenBank:YP_010377160.1,GeneID:72551574;Name=OPG188;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp165%3B schlafen-like%3B similar to VACV-WR B4R and VACV-Cop B2R;gbkey=CDS;gene=OPG188;locus_tag=NBT03_gp158;product=Schlafen (1);protein_id=YP_010377160.1 +NC_063383.1 RefSeq gene 163333 165018 . + . ID=gene-NBT03_gp159;Dbxref=GeneID:72551575;Name=OPG189;gbkey=Gene;gene=OPG189;gene_biotype=protein_coding;locus_tag=NBT03_gp159;old_locus_tag=MPXV-M5312_HM12_Rivers-165 +NC_063383.1 RefSeq CDS 163333 165018 . + 0 ID=cds-YP_010377161.1;Parent=gene-NBT03_gp159;Dbxref=GenBank:YP_010377161.1,GeneID:72551575;Name=OPG189;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp166%3B ankyrin-like%3B similar to VACV-WR B5R and VACV-Cop B4R;gbkey=CDS;gene=OPG189;locus_tag=NBT03_gp159;product=Ankyrin repeat protein (25);protein_id=YP_010377161.1 +NC_063383.1 RefSeq gene 165122 166075 . + . ID=gene-NBT03_gp160;Dbxref=GeneID:72551576;Name=OPG190;gbkey=Gene;gene=OPG190;gene_biotype=protein_coding;locus_tag=NBT03_gp160;old_locus_tag=MPXV-M5312_HM12_Rivers-166 +NC_063383.1 RefSeq CDS 165122 166075 . + 0 ID=cds-YP_010377162.1;Parent=gene-NBT03_gp160;Dbxref=GenBank:YP_010377162.1,GeneID:72551576;Name=OPG190;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp167%3B palmitated 42 kDa glycoprotein located both on the membranes of infected cells and on EEV envelope%3B complement control protein-like%3B EEV type-1 membrane glycoprotein%2C protective antigen%3B similar to VACV-WR B6R and VACV-Cop B5R;gbkey=CDS;gene=OPG190;locus_tag=NBT03_gp160;product=EEV type-I membrane glycoprotein;protein_id=YP_010377162.1 +NC_063383.1 RefSeq gene 166161 166667 . + . ID=gene-NBT03_gp161;Dbxref=GeneID:72551577;Name=OPG191;gbkey=Gene;gene=OPG191;gene_biotype=protein_coding;locus_tag=NBT03_gp161;old_locus_tag=MPXV-M5312_HM12_Rivers-167 +NC_063383.1 RefSeq CDS 166161 166667 . + 0 ID=cds-YP_010377163.1;Parent=gene-NBT03_gp161;Dbxref=GenBank:YP_010377163.1,GeneID:72551577;Name=OPG191;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp168%3B Ankyrin-like protein%3B similar to VACV-WR B7R and VACV-Cop B6R;gbkey=CDS;gene=OPG191;locus_tag=NBT03_gp161;product=Ankyrin-like protein (46);protein_id=YP_010377163.1 +NC_063383.1 RefSeq gene 166731 167279 . + . ID=gene-NBT03_gp162;Dbxref=GeneID:72551578;Name=OPG192;gbkey=Gene;gene=OPG192;gene_biotype=protein_coding;locus_tag=NBT03_gp162;old_locus_tag=MPXV-M5312_HM12_Rivers-168 +NC_063383.1 RefSeq CDS 166731 167279 . + 0 ID=cds-YP_010377164.1;Parent=gene-NBT03_gp162;Dbxref=GenBank:YP_010377164.1,GeneID:72551578;Name=OPG192;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp169%3B Virulence%2C ER resident%3B similar to VACV-WR B8R and VACV-Cop B7R;gbkey=CDS;gene=OPG192;locus_tag=NBT03_gp162;product=Virulence protein;protein_id=YP_010377164.1 +NC_063383.1 RefSeq gene 167334 168137 . + . ID=gene-NBT03_gp163;Dbxref=GeneID:72551579;Name=OPG193;gbkey=Gene;gene=OPG193;gene_biotype=protein_coding;locus_tag=NBT03_gp163;old_locus_tag=MPXV-M5312_HM12_Rivers-169 +NC_063383.1 RefSeq CDS 167334 168137 . + 0 ID=cds-YP_010377165.1;Parent=gene-NBT03_gp163;Dbxref=GenBank:YP_010377165.1,GeneID:72551579;Name=OPG193;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp170%3B secreted IFN-g binding protein%3B Soluble IFN-g receptor-like protein%3B similar to VACV-WR B9R and VACV-Cop B8R;gbkey=CDS;gene=OPG193;locus_tag=NBT03_gp163;product=Soluble interferon-gamma receptor-like protein;protein_id=YP_010377165.1 +NC_063383.1 RefSeq gene 168230 168895 . + . ID=gene-NBT03_gp164;Dbxref=GeneID:72551580;Name=OPG195;gbkey=Gene;gene=OPG195;gene_biotype=protein_coding;locus_tag=NBT03_gp164;old_locus_tag=MPXV-M5312_HM12_Rivers-170 +NC_063383.1 RefSeq CDS 168230 168895 . + 0 ID=cds-YP_010377166.1;Parent=gene-NBT03_gp164;Dbxref=GenBank:YP_010377166.1,GeneID:72551580;Name=OPG195;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp171%3B shope fibroma virus T4 protein-like%3B ER-localized apoptosis regulator%3B similar to VACV-WR B10R and VACV-Cop B9R;gbkey=CDS;gene=OPG195;locus_tag=NBT03_gp164;product=Intracellular viral protein;protein_id=YP_010377166.1 +NC_063383.1 RefSeq sequence_feature 169001 169642 . + . ID=id-NC_063383.1:169001..169642;exon_number=OPG196;gbkey=misc_feature;number=OPG196 +NC_063383.1 RefSeq gene 169670 169972 . + . ID=gene-NBT03_gp165;Dbxref=GeneID:72551581;Name=OPG197;gbkey=Gene;gene=OPG197;gene_biotype=protein_coding;locus_tag=NBT03_gp165;old_locus_tag=MPXV-M5312_HM12_Rivers-171 +NC_063383.1 RefSeq CDS 169670 169972 . + 0 ID=cds-YP_010377167.1;Parent=gene-NBT03_gp165;Dbxref=GenBank:YP_010377167.1,GeneID:72551581;Name=OPG197;Note=Taxonomic breadth: chordopoxvirinae%3B Hypothetical protein%3B similar to VACV-Cop-B11R;gbkey=CDS;gene=OPG197;locus_tag=NBT03_gp165;product=CPXV205 protein;protein_id=YP_010377167.1 +NC_063383.1 RefSeq gene 170038 170886 . + . ID=gene-NBT03_gp166;Dbxref=GeneID:72551582;Name=OPG198;gbkey=Gene;gene=OPG198;gene_biotype=protein_coding;locus_tag=NBT03_gp166;old_locus_tag=MPXV-M5312_HM12_Rivers-172 +NC_063383.1 RefSeq CDS 170038 170886 . + 0 ID=cds-YP_010377168.1;Parent=gene-NBT03_gp166;Dbxref=GenBank:YP_010377168.1,GeneID:72551582;Name=OPG198;Note=Taxonomic breadth: poxviridae%3B protein kinase-like%3B similar to VACV-WR B11R and VACV-Cop B12R;gbkey=CDS;gene=OPG198;locus_tag=NBT03_gp166;product=Ser/thr kinase;protein_id=YP_010377168.1 +NC_063383.1 RefSeq gene 170988 172022 . + . ID=gene-NBT03_gp167;Dbxref=GeneID:72551583;Name=OPG199;gbkey=Gene;gene=OPG199;gene_biotype=protein_coding;locus_tag=NBT03_gp167;old_locus_tag=MPXV-M5312_HM12_Rivers-173 +NC_063383.1 RefSeq CDS 170988 172022 . + 0 ID=cds-YP_010377169.1;Parent=gene-NBT03_gp167;Dbxref=GenBank:YP_010377169.1,GeneID:72551583;Name=OPG199;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp173%3B serine protease inhibitor-like%2C SPI-2%3B inhibition of the IL-1b converting enzyme%3B apoptosis inhibition%3B Serpin 1%2C2%2C3%3B similar to VACV-WR B12R and VACV-Cop K2L;gbkey=CDS;gene=OPG199;locus_tag=NBT03_gp167;product=Serpin;protein_id=YP_010377169.1 +NC_063383.1 RefSeq gene 172150 172599 . + . ID=gene-NBT03_gp168;Dbxref=GeneID:72551584;Name=OPG200;gbkey=Gene;gene=OPG200;gene_biotype=protein_coding;locus_tag=NBT03_gp168;old_locus_tag=MPXV-M5312_HM12_Rivers-174 +NC_063383.1 RefSeq CDS 172150 172599 . + 0 ID=cds-YP_010377170.1;Parent=gene-NBT03_gp168;Dbxref=GenBank:YP_010377170.1,GeneID:72551584;Name=OPG200;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp174%3B Hypothetical protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR B13R and VACV-Cop C16L and B15R;gbkey=CDS;gene=OPG200;locus_tag=NBT03_gp168;product=Bcl-2-like protein;protein_id=YP_010377170.1 +NC_063383.1 RefSeq sequence_feature 172685 173697 . + . ID=id-NC_063383.1:172685..173697;exon_number=OPG201;gbkey=misc_feature;number=OPG201 +NC_063383.1 RefSeq sequence_feature 173744 174187 . - . ID=id-NC_063383.1:173744..174187;exon_number=OPG202;gbkey=misc_feature;number=OPG202 +NC_063383.1 RefSeq sequence_feature 174328 174456 . + . ID=id-NC_063383.1:174328..174456;exon_number=OPG203;gbkey=misc_feature;number=OPG203 +NC_063383.1 RefSeq gene 174532 175587 . + . ID=gene-NBT03_gp169;Dbxref=GeneID:72551585;Name=OPG204;gbkey=Gene;gene=OPG204;gene_biotype=protein_coding;locus_tag=NBT03_gp169;old_locus_tag=MPXV-M5312_HM12_Rivers-177 +NC_063383.1 RefSeq CDS 174532 175587 . + 0 ID=cds-YP_010377172.1;Parent=gene-NBT03_gp169;Dbxref=GenBank:YP_010377172.1,GeneID:72551585;Name=OPG204;Note=Taxonomic breadth: orthopoxvirus%3B Old product: MPXVgp177%3B cell surface antigen and secreted IFN-a%3B IFN-alpha/beta receptor glycoprotein%3B similar to VACV-WR B16R and VACV-Cop B19R;gbkey=CDS;gene=OPG204;locus_tag=NBT03_gp169;product=IFN-alpha/beta-receptor-like secreted glycoprotein;protein_id=YP_010377172.1 +NC_063383.1 RefSeq gene 175656 178019 . + . ID=gene-NBT03_gp170;Dbxref=GeneID:72551586;Name=OPG205;gbkey=Gene;gene=OPG205;gene_biotype=protein_coding;locus_tag=NBT03_gp170;old_locus_tag=MPXV-M5312_HM12_Rivers-178 +NC_063383.1 RefSeq CDS 175656 178019 . + 0 ID=cds-YP_010377173.1;Parent=gene-NBT03_gp170;Dbxref=GenBank:YP_010377173.1,GeneID:72551586;Name=OPG205;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp178%3B ankyrin-like%3B similar to VACV-WR B17R and VACV-Cop B20R;gbkey=CDS;gene=OPG205;locus_tag=NBT03_gp170;product=Ankyrin repeat protein (44);protein_id=YP_010377173.1 +NC_063383.1 RefSeq sequence_feature 178118 178916 . + . ID=id-NC_063383.1:178118..178916;exon_number=OPG206;gbkey=misc_feature;number=OPG206 +NC_063383.1 RefSeq gene 179266 180339 . + . ID=gene-NBT03_gp171;Dbxref=GeneID:72551587;Name=OPG208;gbkey=Gene;gene=OPG208;gene_biotype=protein_coding;locus_tag=NBT03_gp171;old_locus_tag=MPXV-M5312_HM12_Rivers-180 +NC_063383.1 RefSeq CDS 179266 180339 . + 0 ID=cds-YP_010377174.1;Parent=gene-NBT03_gp171;Dbxref=GenBank:YP_010377174.1,GeneID:72551587;Name=OPG208;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp180%3B serine protease inhibitor-like%2C SPI-1%3B apoptosis inhibition%3B Serpin 1%2C2%2C3%3B Actual start may be at position 179%2C074%3B annotated start of ORF is missing approx. 17 AA compared to CPXVs%3B similar to VACV-WR B19R and VACV-Cop K2L;gbkey=CDS;gene=OPG208;locus_tag=NBT03_gp171;product=Serpin;protein_id=YP_010377174.1 +NC_063383.1 RefSeq gene 180518 181090 . + . ID=gene-NBT03_gp172;Dbxref=GeneID:72551588;Name=OPG209;gbkey=Gene;gene=OPG209;gene_biotype=protein_coding;locus_tag=NBT03_gp172;old_locus_tag=MPXV-M5312_HM12_Rivers-181 +NC_063383.1 RefSeq CDS 180518 181090 . + 0 ID=cds-YP_010377175.1;Parent=gene-NBT03_gp172;Dbxref=GenBank:YP_010377175.1,GeneID:72551588;Name=OPG209;Note=Old product: MPXVgp181%3B Hypothetical protein%3B similar to VACV-WR B20R and VACV-Cop C14L;gbkey=CDS;gene=OPG209;locus_tag=NBT03_gp172;product=Virulence protein;protein_id=YP_010377175.1 +NC_063383.1 RefSeq gene 181356 186998 . + . ID=gene-NBT03_gp173;Dbxref=GeneID:72551589;Name=OPG210;gbkey=Gene;gene=OPG210;gene_biotype=protein_coding;locus_tag=NBT03_gp173;old_locus_tag=MPXV-M5312_HM12_Rivers-182 +NC_063383.1 RefSeq CDS 181356 186998 . + 0 ID=cds-YP_010377176.1;Parent=gene-NBT03_gp173;Dbxref=GenBank:YP_010377176.1,GeneID:72551589;Name=OPG210;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp182%3B Surface glycoprotein%3B putative membrane-associated glycoprotein%3B cadherin-like domain%3B similar to VACV-WR B21R;gbkey=CDS;gene=OPG210;locus_tag=NBT03_gp173;product=B22R family protein;protein_id=YP_010377176.1 +NC_063383.1 RefSeq sequence_feature 187317 187743 . + . ID=id-NC_063383.1:187317..187743;exon_number=OPG212;gbkey=misc_feature;number=OPG212 +NC_063383.1 RefSeq sequence_feature 187822 188298 . + . ID=id-NC_063383.1:187822..188298;exon_number=OPG213;gbkey=misc_feature;number=OPG213 +NC_063383.1 RefSeq sequence_feature 188458 188963 . + . ID=id-NC_063383.1:188458..188963;exon_number=OPG214;gbkey=misc_feature;number=OPG214 +NC_063383.1 RefSeq gene 189199 189660 . + . ID=gene-NBT03_gp174;Dbxref=GeneID:72551590;Name=OPG005;gbkey=Gene;gene=OPG005;gene_biotype=protein_coding;locus_tag=NBT03_gp174;old_locus_tag=MPXV-M5312_HM12_Rivers-184 +NC_063383.1 RefSeq CDS 189199 189660 . + 0 ID=cds-YP_010377177.1;Parent=gene-NBT03_gp174;Dbxref=GenBank:YP_010377177.1,GeneID:72551590;Name=OPG005;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp185%3B VAC B15R-like%3B Hypothetical protein%3B Putative tlr signaling inhibitor%3B similar to VACV-WR N1R and VACV-Cop C16L and B22R;gbkey=CDS;gene=OPG005;locus_tag=NBT03_gp174;product=Bcl-2-like protein;protein_id=YP_010377177.1 +NC_063383.1 RefSeq gene 190410 190940 . + . ID=gene-NBT03_gp175;Dbxref=GeneID:72551591;Name=OPG016;gbkey=Gene;gene=OPG016;gene_biotype=protein_coding;locus_tag=NBT03_gp175;old_locus_tag=MPXV-M5312_HM12_Rivers-186 +NC_063383.1 RefSeq CDS 190410 190940 . + 0 ID=cds-YP_010377184.1;Parent=gene-NBT03_gp175;Dbxref=GenBank:YP_010377184.1,GeneID:72551591;Name=OPG016;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp187%3B similar to VACV-WR N3R;gbkey=CDS;gene=OPG016;locus_tag=NBT03_gp175;product=Brix domain protein;protein_id=YP_010377184.1 +NC_063383.1 RefSeq long_terminal_repeat 190788 197209 . + . ID=id-NC_063383.1:190788..197209;gbkey=repeat_region;rpt_type=long_terminal_repeat +NC_063383.1 RefSeq gene 191054 192367 . + . ID=gene-NBT03_gp176;Dbxref=GeneID:72551592;Name=OPG015_dup;gbkey=Gene;gene=OPG015_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp176;old_locus_tag=MPXV-M5312_HM12_Rivers-187 +NC_063383.1 RefSeq CDS 191054 192367 . + 0 ID=cds-YP_010377179.1;Parent=gene-NBT03_gp176;Dbxref=GenBank:YP_010377179.1,GeneID:72551592;Name=OPG015_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp188%3B ankyrin-like%3B Ankyrin (CPXV-017)%3B similar to VACV-WR N4R;gbkey=CDS;gene=OPG015_dup;locus_tag=NBT03_gp176;product=Ankyrin repeat protein (39);protein_id=YP_010377179.1 +NC_063383.1 RefSeq gene 192603 194369 . + . ID=gene-NBT03_gp177;Dbxref=GeneID:72551593;Name=OPG003_dup;gbkey=Gene;gene=OPG003_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp177;old_locus_tag=MPXV-M5312_HM12_Rivers-188 +NC_063383.1 RefSeq CDS 192603 194369 . + 0 ID=cds-YP_010377180.1;Parent=gene-NBT03_gp177;Dbxref=GenBank:YP_010377180.1,GeneID:72551593;Name=OPG003_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp189%3B ankyrin-like%3B similar to VACV-WR J1R and VACV-Cop C19L;gbkey=CDS;gene=OPG003_dup;locus_tag=NBT03_gp177;product=Ankyrin repeat protein (25);protein_id=YP_010377180.1 +NC_063383.1 RefSeq gene 194459 195508 . + . ID=gene-NBT03_gp178;Dbxref=GeneID:72551594;Name=OPG002_dup;gbkey=Gene;gene=OPG002_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp178;old_locus_tag=MPXV-M5312_HM12_Rivers-189 +NC_063383.1 RefSeq CDS 194459 195508 . + 0 ID=cds-YP_010377181.1;Parent=gene-NBT03_gp178;Dbxref=GenBank:YP_010377181.1,GeneID:72551594;Name=OPG002_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp190%3B secreted TNF binding protein%3B TNF receptor (CrmB)%3B similar to VACV-WR J2R and VACV-Cop C22L;gbkey=CDS;gene=OPG002_dup;locus_tag=NBT03_gp178;product=Crm-B secreted TNF-alpha-receptor-like protein;protein_id=YP_010377181.1 +NC_063383.1 RefSeq gene 195635 196375 . + . ID=gene-NBT03_gp179;Dbxref=GeneID:72551595;Name=OPG001_dup;gbkey=Gene;gene=OPG001_dup;gene_biotype=protein_coding;locus_tag=NBT03_gp179;old_locus_tag=MPXV-M5312_HM12_Rivers-190 +NC_063383.1 RefSeq CDS 195635 196375 . + 0 ID=cds-YP_010377182.1;Parent=gene-NBT03_gp179;Dbxref=GenBank:YP_010377182.1,GeneID:72551595;Name=OPG001_dup;Note=Taxonomic breadth: chordopoxvirinae%3B Old product: MPXVgp191%3B Chemokine binding protein (Cop-C23L)%3B most abundant secreted protein%3B CC-chemokine binding protein%3B similar to VACV-WR J3R and VACV-Cop C23L and B29R;gbkey=CDS;gene=OPG001_dup;locus_tag=NBT03_gp179;product=Chemokine binding protein;protein_id=YP_010377182.1 diff --git a/data_output/nextstrain/mpox/lineage-b.1/unreleased/pathogen.json b/data_output/nextstrain/mpox/lineage-b.1/unreleased/pathogen.json new file mode 100644 index 00000000..6b453c98 --- /dev/null +++ b/data_output/nextstrain/mpox/lineage-b.1/unreleased/pathogen.json @@ -0,0 +1,284 @@ +{ + "alignmentParams": { + "excessBandwidth": 40, + "terminalBandwidth": 200, + "allowedMismatches": 5, + "windowSize": 30, + "minSeedCover": 0.1, + "gapAlignmentSide": "left" + }, + "attributes": { + "name": "Mpox virus (Lineage B.1)", + "reference accession": "NC_063383.1 (with B.1 SNPs)", + "reference name": "MPXV-M5312_HM12_Rivers with B.1 SNPs" + }, + "compatibility": { + "cli": "3.0.0-alpha.0", + "web": "3.0.0-alpha.0" + }, + "deprecated": false, + "enabled": true, + "experimental": false, + "files": { + "changelog": "CHANGELOG.md", + "examples": "sequences.fasta", + "genomeAnnotation": "genome_annotation.gff3", + "pathogenJson": "pathogen.json", + "readme": "README.md", + "reference": "reference.fasta", + "treeJson": "tree.json" + }, + "mutLabels": { + "nucMutLabelMap": { + "100261A": [ + "rev" + ], + "119296C": [ + "rev" + ], + "121320C": [ + "rev" + ], + "124130G": [ + "rev" + ], + "124674G": [ + "rev" + ], + "125249G": [ + "rev" + ], + "1262G": [ + "rev" + ], + "128698C": [ + "rev" + ], + "14000G": [ + "rev" + ], + "148412G": [ + "rev" + ], + "150469C": [ + "rev" + ], + "151461A": [ + "rev" + ], + "15428G": [ + "rev" + ], + "154408T": [ + "rev" + ], + "155795G": [ + "rev" + ], + "162243G": [ + "rev" + ], + "162331C": [ + "rev" + ], + "164832C": [ + "rev" + ], + "168120C": [ + "rev" + ], + "170262G": [ + "rev" + ], + "178133G": [ + "rev" + ], + "181980G": [ + "rev" + ], + "183519C": [ + "rev" + ], + "186578G": [ + "rev" + ], + "187428C": [ + "rev" + ], + "18769A": [ + "rev" + ], + "193392G": [ + "rev" + ], + "193688C": [ + "rev" + ], + "194099C": [ + "rev" + ], + "194619C": [ + "rev" + ], + "195948C": [ + "rev" + ], + "21723G": [ + "rev" + ], + "23564C": [ + "rev" + ], + "25661G": [ + "rev" + ], + "2591G": [ + "rev" + ], + "28175T": [ + "rev" + ], + "30367G": [ + "rev" + ], + "31053G": [ + "rev" + ], + "3111G": [ + "rev" + ], + "34459G": [ + "rev" + ], + "3522G": [ + "rev" + ], + "37202G": [ + "rev" + ], + "3818C": [ + "rev" + ], + "38360G": [ + "rev" + ], + "38662C": [ + "rev" + ], + "39119C": [ + "rev" + ], + "39139C": [ + "rev" + ], + "52885G": [ + "rev" + ], + "54117G": [ + "rev" + ], + "54635G": [ + "rev" + ], + "64297G": [ + "rev" + ], + "72362C": [ + "rev" + ], + "73066C": [ + "rev" + ], + "73239G": [ + "rev" + ], + "74205G": [ + "rev" + ], + "77383G": [ + "rev" + ], + "7771C": [ + "rev" + ], + "81275G": [ + "rev" + ], + "81977A": [ + "rev" + ], + "82373C": [ + "rev" + ], + "82451G": [ + "rev" + ], + "83326C": [ + "rev" + ], + "84587C": [ + "rev" + ], + "87230G": [ + "rev" + ], + "87297G": [ + "rev" + ], + "91728G": [ + "rev" + ], + "95034G": [ + "rev" + ] + } + }, + "official": true, + "qc": { + "frameShifts": { + "enabled": true, + "scoreWeight": 20 + }, + "missingData": { + "enabled": true, + "missingDataThreshold": 20000, + "scoreBias": 1000 + }, + "mixedSites": { + "enabled": true, + "mixedSitesThreshold": 40 + }, + "privateMutations": { + "cutoff": 50, + "enabled": true, + "typical": 5, + "weightLabeledSubstitutions": 6, + "weightReversionSubstitutions": 6, + "weightUnlabeledSubstitutions": 1 + }, + "snpClusters": { + "clusterCutOff": 5, + "enabled": true, + "scoreWeight": 20, + "windowSize": 100 + }, + "stopCodons": { + "enabled": true, + "ignoredStopCodons": [ + { + "codon": 187, + "geneName": "OPG015_dup" + }, + { + "codon": 187, + "geneName": "OPG015" + } + ], + "scoreWeight": 40 + } + }, + "schemaVersion": "3.0.0", + "version": { + "tag": "unreleased" + } +} diff --git a/data_output/nextstrain/mpox/lineage-b.1/unreleased/reference.fasta b/data_output/nextstrain/mpox/lineage-b.1/unreleased/reference.fasta new file mode 100644 index 00000000..a69fa925 --- /dev/null +++ b/data_output/nextstrain/mpox/lineage-b.1/unreleased/reference.fasta @@ -0,0 +1,2 @@ +>ref_in_coord MPXV_USA_2022_MA001 sequence in NC_063383 coordinates +ATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTTGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGAGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGAGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAAT diff --git a/data_output/nextstrain/mpox/lineage-b.1/unreleased/sequences.fasta b/data_output/nextstrain/mpox/lineage-b.1/unreleased/sequences.fasta new file mode 100644 index 00000000..40dd888e --- /dev/null +++ b/data_output/nextstrain/mpox/lineage-b.1/unreleased/sequences.fasta @@ -0,0 +1,18 @@ +>MPXV_USA_2022_MA001 | ON563414.2 +TATTATATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCRAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTTGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGAGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGAGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATATAATA +>Monkeypox/PT0001/2022|sampling_date_20220504_v2 +CGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGNAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACNTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTNAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACNGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCNTTTGAGAAGACAATAATATCCTNGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTANGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACNGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTNAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAANNGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTANGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCNNNTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTANCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTAACTAACTTATGANTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAANACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATANTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATNAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATNAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATNCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCNAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTNNAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATNAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCNTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATNAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTANTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCNTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCNNTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCNGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTNNTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTNGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCANTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTNAATACATCTATATTANGATTTGATGTTGTCGCGTANTNNTCTACAATATTAATACCANTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTNAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAANNNATTNATATTTTTATAGTCGACTGACGACAATAACAAAATNACNACATCNTTTTTGANNNNNNNNNNNTTTNNNNTAACGTATGCCTTTNNTGGANNNTCACCATCATACNCNNATAATGGATTTGCACCACTTTCTATTAATGATTNTNNACTACTGGCANCGATGTTAAATGNNTTACAACTATCATAGNGTATNNTATCGTTAACCATGATTGGTTGTTGATGTTATCACANNTTTTTGGTNNNTTTCATTTCAGNTANNTATGGATTTAGCACGTTTNGGAAGCANGNGCTCNNATGATTTCAGTACTGTAGTGTCAGTNNTATTAGTTTCGNTCAGATCAATGTCTAGATCTATAGAATCNAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCNTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTAGTATAAAATTCTATATTCAAATTATCATGCGANNTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAANNAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGNTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCNTGTAATCATTCGAAATAANTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGNGGAATCAGTTANGAANAAAAAATTATCTGTCATCATCATCATCTATTNGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTNGATACATCACGACCNTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCNTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAANTTTTTATGGTATAGATCCNNTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTANCTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCNTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTNGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATNAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTANGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTANGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCNAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCNAATACTTNGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAANNAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAANCNGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTNGATCTGCGCNGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCNAAACAACATATACACATTTAATNAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTANGAGCCATCATTTCGGCTATCGACTTAATATNCCTCTTGTTTTCGATAGAAAATCTANNGAGNTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGNGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCNTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGNAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTNAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATNCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCNTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGNAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAANTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCNTTTTAAGCCAAAATATGGAAGCGAATGATCCGGNAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCNTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTNNTTCCACTGTCCAAAATGATGNCTCTGCCNTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAANTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTNCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTNNAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCNCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAANTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGNTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGNTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTNAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCNAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTNAAAAGTTGTCACAACAGGGTNGTTCGTAGATTTTANNGTATAACNGAGACATNNNTNNAAAGATAAACTTTNTGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTNNNTCGGTATCTACTTTATCTGCCGAATACAGTGCTNNNGNNAAAATTATAATNTTTNNNCTTTCGTATTCGTAATTNGTTCNCTTTTCATGTTCGNAAAAGTGAAACNTGCGGTTAAAATNGTTTATAACATTAATATTACTGTTNNNNNCTGNCGGATNAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTNNNNTCGTTAAACGCCTTTAGNAAAACTNNNGAAGAATATCTCAATGNGAGTTCCTGACCATCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTCATCTNCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCNNCGTAGTTTCCATGGGACTATANNNNNNTGTNNCCTNGAATNNNNNNTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCNNCCTGTAGATATGTGATNAAAATCGTCGTTTATAGGATAAANNCGTTTATCNNTTTGTTGNNNAAAGGATGAATTAATGTAATCATTCNNNTCTATCTTTAGTAGTGNTTCCNTATTAAAATTNTTAAAATAATTTAACAATCTAACTGACGGAGCCCNNNNTTNGTGTNAATCTAATTGGGACATTANNTTGTTAAAATATAAANNNTCTCCTAATATAACAGTATCTGATAANCTATNGGGAGNCATCCATTGATATTCANGGGATGAATCATTNGNAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCNTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTNCAATTGTTGCCTGTATTGTATTANAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTANGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCANTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAANCANNAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACNATGNNCGGNTTAATGTNNTATGTAACATTGAGTAAATNCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATNCAAACAATGTTTCTANCGGCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNNCGAATCAGTAACTATGTTCANNTTTTTANNNGTANGACGTCTAGCCAGTATNGANNAGGATTTTCNAGATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTCTATGAGTTGTTNCAATAAATTATTTGTTGTGACTGCGTTCAAGNCATAAATTANNTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCNCTGATAGCAGTTTNAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCNTTTGTACCANTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTNAGAACATGTCTTCTATTCTNGAAAACGAAAACATCCTNNATNGACTCATTAAAACTTNTAACGNNCCNGNTTGTGTTTCNAATGCCTNNNNCAAGGANNTCAAGGATGCCATAGATNNTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGANTTTTTTATTAAATCAAATNGTCGGCTCTCTGGTTTACTACCCCAANGATAACAATAGTCTTGTAAAGATANNNNNNNNNNNNNNNNNNNNNNNNCCATCCAAATAANCCTANNANCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCNTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAANTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAANTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATANTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTNAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACANTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACNTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTANGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGNATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTNCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCNNNAAAAAATCNTTTTTNATTNNTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCNTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACNTATTCAGAGTTGTTGTTCAAATAGATNCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGNNNTGCGGACATTAAACGATTTGATGAGTTAGATATTAATNACNNNNATATATCTAATATAATTTATGAGGTGAACGATNNNACATTAGATACAATGGATGATATNAAGAAGTGTCAAATCNTTAACGAGGATACGNNGTATTATGTTAAGGAATACAATACATACCTGNTTTTGCACNAGTCNGATCCCATGGTCNNAGAGAACGGAATACTAAAGAAACTGTCATCNATAAAATCCAAGAGTAGACGGCTNNACTTGNTTAGCNAAAACATTNNNAANNNNTATTTNNACGGACAATTNGCTCGTCTAGGTCNNNTGTTNGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGNGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAANCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGNTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTNNAGAGATAATCTATATCATGTAGAAGAATTCTTNGATNAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTGATAAATGNNNACCGTTGCNACANNTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATANTTTAACCTGATGTNNTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAANNNGTAGGATATNAATATTATGGCCGCAACCGTTCCGCGNTTTGACGANNTGTANAAAAATGCACAAAGAAGAATTNTAGATCNAGNAACANNTTTNNGTAGAGGTCTNNNTAGACCGTTAATGNAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCNNTATAAANGTCCTATTNNCGTATATGAAGNAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTNCGGTAGATACGTATCATATCTTNNAAAGTTTTCNNNCCTTCCAACAAACGAGTTTATTANNNNNTTANTATTGACCTCCATCCCTATCTNNNATATCNTATTCTNGTTTNNAANNACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCNTGCGTTGGCTANGTATATACATCAAACAGGAGACTATNNGNCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTNGTCCCGTTCCAATAGGTATCNAAGATATAGATCACCCTAATCNTAGTAGAGCANNAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGNTTTTATTGNTTTACGTACCTGGGTATTCAATTACTACNNNNNNTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACNAAGAGCGACGTACAANTNTNNTAAATTATTTTATGCTTCNNAAAATGTAGGTCTTGAACCAAACATTCTTTGNAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATNGTTTNNAGNAAACTNNNTAAAATATTCTTTGATTGCTGCCGAGNTTAAAACTTNTATCGATAATTGTTTCNNNNGTTTTAATATTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAACCAAATACATATTANGGTTATCTGCGGATTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTATTAATCNGTCGTTCNAACTCCTTTGNTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCNGTNAACACNGAGTCGGTANNTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATNTCTATCGTCCATATAAAATGGATTACTTAATGTATTNGCNAACCGTAACATACCGTTNGATNNCTCNGNTCCATTTAGTACCNANNCNAGATACAATATCATTCTACGTCCTATGGANNTGCAACTCTTAGCCNAAGNGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTANNNTGNTTTAANNNNNTTTTATATNNNNNNNNNTNNNCCNAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTNNTGAAGCAAGAGTTGATTATTTATNNNTTCTTNCNATCTNTTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATNNNNNNNNNNNNNNNNNNNNNNNNNGATACAGACNNNTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGNTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCNNAGTATNGTCACCGATGAACGTCATTNNNNTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTNGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGANTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATNATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCNTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACANNNNNTCATTAATGANNGTAAACNNNAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGANCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTNAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGNTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATNTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTANTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCNAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTNGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACANTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGNAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATNTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTNCCCTGTCTGCAGCCATTTTTANGNTCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCNCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATNCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCNTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTNCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCNCAACATTNGAATAATACCGTTTGATATACCATTNGTACCNGAGATATAGCTTCCACTNGCACGAATATNNNTAATTGATAGACCTATTNCCCCTNCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCNATGCTATCATCGATCATGTTAAGTNGAAAACAGCTAGACATTTGGTGACGNGTNGTTNCCGCATTNAANAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAANTTTTAAAACCAAAATAGTTGTANGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCNGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTANNATGGCGGTGCCAGAAATTACCATCNAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTNNNTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTNNTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCNTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCNTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCNGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTNANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAATATTTCGATGATATACGGTAGTCTCTCNTTCNGACTTNTATAGCNTATTNCACAATACGAGTCATTATATACNCCNNAAAANNNAATNNNTAGTATNAAATCNGTATCGAATGGNNAAAACGAAATTATCGATATAGGNNTAGAANCNNGAACATTGAACGTATTAATACTTAATNNTTTTTCANNNNNAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTNNGACTTGATAGATATTAANGACGAATTGNAAATTANTTTTATNACCACNNGTGNNTCAGGANCNTNGTCGANNNCAGTTAACCAACCGAATGGAGTANNNNAAATATCATTAATATATGCNCTAGATATTAGTANNNNNNTTAANNCTTTGATTATCATCTNNTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGNNCATCCTCCNGAGTATTAATNGGTTTAGTAAACAGTCCANCGTTGCNATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCNNNCGNTTAAAGATNNNACCTCATCTAACGGAGACAANNTTNNNGTAGGNTTTNNAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACNTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCANTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGNAAAAGAATAGAAATNAAAATTATTATAATGGTGGAATTCAGTTNGAATATTGNCTCCNGAGTCATNAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTNCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACNTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCNTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGNGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGNAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTANGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCNAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCNAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGNAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTANTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCNTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACNTTTGTAGAATATTATTCNGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTNAAAATCAAAATCTAATGACCACATCNNTTTTTAGAGATGNAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGNAAAAANTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCNATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGNTTTGATCTACTATACTTTNAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTNCTTCGGCATTTCNNTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGANNCGTCTNNGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTANGGGTATACTTCNATAAGGTTTNTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTNGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGNGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTANNTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTANAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTNTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCNAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCNTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTNAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGNAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCNNGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCNGAAGTTAAAACTTTATCATCTNNTATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGNAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTNGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTNATTTGAATCCATCGATAGAAAAACANNTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTNGATAGATTTTTTNNANGATATCTTAGTGCNAAAGTATACATGTTAGAGAATATTCNAGTTATGAAAATAGNAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATNAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGNGTATTTNTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTANTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTNTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATANTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTNGCAACAATTGTAGATACCATTAATCACTGATTCCNNTTTCGATNNNGGACAATAGCACAATTGTTTAGCNNTNGACTCTANNTATNNAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATNAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTNTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCNTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTNCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAANCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACNGCACCCAATTGCTGTCGCACNTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGNTGATTTATTCGACTGGTGTCANGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTANNTCTCTTNNTNATATGGATACTAATTGTAGCTATTTAAATGNGTGCCGCANCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTNAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGNNAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTANNTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCNGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTANTAATCTTCTTTGGGCACATATACCAGTNTACCAGGTTCTNNNAACCTANTTACTGGTGCTCCTGTAGNATACNNNNNTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTANNACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGNAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCNGGGTTAATCTCACAACTTTACTGNTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATNCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCNGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCNAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTNAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGNAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATANTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGNAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATNCCACAGAACTAATGTATATTCTAGGTACTTNTGGACAACNNAGGATAGATNNNGAANCAGCAGAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATGGTTCTTCCAGGTGNCGCCAACANGGGNNANNTTAGTAAATTCNAGATTCCTATCTCTGACTATACGGGATATAACGACNTCAATCAAACNAAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTAGTTACGANNCAGAATCANTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTANNAGAGNNNCGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCNTAAAAAGTCAGAACCTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAANGAAACTATCTGATAAGATATCTTCTCNAAAGATCNAGGAGATAGNAGAAACNGNAGACNTTTAATTCTTATCNNNAACATANTTTTCNATGATCTGTCTTTTAAACGATNGATTTTNCACAAATGCGCCTCTCNANTCCCTCATAGAATGATNNACGNATNNANNNNATAGCATAGGTNATGANNCCTTATTTTTAGACATTAGATATNNNAAAATCATAGCCCNNCTTCTATTTACTNCTGCAACACAATGAACCAACACNGGCTCGNTTNGTTGATCACATNNNGANAAGAAGGCGGTCNCNTCGTCAAAANNNTTACTAATATCNGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATNNACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGNCAAGACATCAACACTTATANTTTTTGTTATTATATTGGCAATTAGTNNGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACNAGATATATGCGAATNAAAAATACNGTTAACGATTNNAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTNAAAAGGCGGCNAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCNAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCNANTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTNAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCNTTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATNCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTNAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACNTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTNAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAANTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACNTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTNNNNAAAAGATCNTNCAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATNAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATNCTATATATGNAAAAATAGCAACCNGTGTTTGATCATNCGCGTCAATATTCTGTTCTATCGTANTNTANAACAATCTTATATCNTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATANTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTNGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAANTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACNAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAANTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCNAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTNGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTNAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTNAGNTTNNATTATCTNNNGTACATGGTCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGATANNATAGTNNNNGNNAAGAAATCATTAGTGACGGAAAATCGTCTTCACNAAGAATGCTTGTTGAGACNATCAACAGAGGAACGTCATATNTTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAANTTTACGATAGACTTTAAGCTAAAATATTTTCTANGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCNCGCTATTAATCATCCNAAGTCAAGGCCTAATANATCTCTNGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTNTTTCTCCACCTATTAACGCACCTATAAAGACNTTTATGTTGCCTAAACAAGATATAGTAGGTCTNGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGNTACATCAAAAGGGTTGNATTGTTANTTTANACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTNAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTNGAGAGTCGTCTATCTTTATAGAGTATANNAAATTTACCAACGATANNNGCTTTNNNAAAGAATATGGTTCTNGTNNGATTGTGTNNTATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGNNATTNAGTNNGTTGTNGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCNAAGCATCAAAATAGGAGATGTCTTTANCGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGNAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCNNTAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCNNNGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCNANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAACNAAGTNNAAAGNTTATTANNNGCGCATCTACAATGGAAGATAGACCGTCTACAANAAACTTTTTCGAACTAAATAGAGGAGCCATTAAANNTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCNTTTCTNNNNNGTNAANAATANNATGGTATNGGTTCTGNTATNCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATNAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGNNATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCNAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTANTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTNNGAAATCACAATGACTTTATCAGATCNAAATTAACAAAATTAAANGAGCATGTANNTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTNAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTNGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATNGAAACAGCCGCTTAGAAATAAACGAGTANNTGTGTGTGGTATAGATCCGTATCCNAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACNAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTANGAGAAACAAAAAGTCACGCGATTTACTNGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATANGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGNAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTNGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAANCCTTGATAACNAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTNAAAAATATACNNGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGNAAAATAGAGAGCTGTATGNNAAAACATTATCTAGTTGNTTATGTGGTGCTACNNNANGATGTTTAACATTCNNNNTTGGAGAAACCGCAANNNNGAAGTCGACAACCAAACGTTTGTTAAAGTNNNCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAANTTTAACAGATGTATTNGANAAAGGACCTAATCCATTTATCGCTAATATGCATTTNNAAAGATCTGTANTCNGTAGNNNACNACCTGNTTTTGCATGTANNGGATCNAAGNNNNTTANATCNNNNNNNNNTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTNCAATAAAATTAATAATANAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATNAGAAGAATTGCCGTCGTGCGATTCAGAACACACNTTTCTCAACCTTCTGGTNNAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACNAAAAATATCATATTNCTATTATGAAACTATATCCTACACCGGAAGAGATTNCGGACTTTGCNTTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTNCNTTAATGACGGACCTCTNNNAAAAGGGATATATATTGTACGATAATGTGGTTANTCTTCCGTTGANTNCTNNNCAACAGAAAATATCCAAGTATTTTAATTNNNNNCTATTTGGNNACGATANNNANAGCTNNATCAATAGACATANGAANNNTNCCAATGTTAGTGATGAATATCTGCANNATATATTCATANNNGATANNTNATCTCCGTAAATATATGCCATATATTTATAGAATATATCACANATCTAAATGAATACCNGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGNTTATCTAGTTNGAANTATCATAGATGAGAACNGAAGCGTGTTATTGTTCCNNATTATNNGATCGGGTAAAACAATAATCGCTTTGTTGTTNNNCTTGGTAGCTTNCAGATTTNNAAAGGTTTACANTTTAGTANCGAACATCAACATCTTAAAAATTTTCAATTATAATATNGGTGTAGCTATGAACNTGTTTAATGACGAATTCATAGCTGNNNATATNNTTATTCATTCCACAACAAGNTTTTATTCTCTTAATTATAACGATAACGTNATTAATTATAACNGATTNNNNCNCTACAATAACTCTANTTTTATCGTTGATGAGGCACATNATATTTTTNGGAATAANNNNNNNGNACTTATGACCGTGATNNNAAATAAAAACAAGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTGAGATTATTAGTCGTGGTNNNNAAGNAATTCAGACACTTCTTAACGAACNCNGAGNGANNNTACNCNNNNATTTGNNTANNNNAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACNNNAGTAGTATATTGTCACATGTCTAAACNNCANNAGAAAGATTANNNGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATNAAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCACTTTNNNNNCTTCTNTAATTCNANATATGGTGGATTGGTAATTAAATATATCATGCTCNNNAATGGATATTCTGAATATAATGGTTCTCANGGNNCTAATCCACATATGATAAACGGCAAACCNAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTNTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCNTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCNTTGACATCNAAAANCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATAATTNTCGTATTAAGTATAACGACTNCAAGTTACTTNAAATGGTTACATCAGTTATAAAAAATAAANAAGACGCTANGAATTACATNNNNGATATTGTAAACGGTCACTTCTTTGTATCGAATNAAGTATTTGATAANNNNCTTTTATACAAATACGAAAACGATATTANTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTNGGGAGTTAANTNNNGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGNNATATAAAGAAATAAATGTCGAGCNTTGTTACCAATGGATATCTTCCAGTTACATTNGAACNNCATGAGNTGACGTTAGACATNAAAACTAATATTANGAATGCCGTATATAAGGCGTATNTCCATAGNNNAATNNGTGGTNAAATGGCCAAGNAAATAGAAATTCGTGAAGACGTGGAATTANNNNTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCNNNTGNANTAACCTACGCATATTATCACGTTNGGGATATAGTCAGAGGAACANNAAACATCGAAGATGAATCNAATGTAACTATTCANNNNNNAGATTTAANCTGTAAACTAAGTAGAGATTCNGGNACTGTATCATTTAGCGATTCNNAGTACNGNNTTTTTCGAAATGNNAANGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTNTCGCGAATATCGTTGACTNANAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTNCCTTCGATATATTTTTGATAATATGNAAAACATGCNNCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCNNATAATCTNCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTNTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCNGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTNGNAAAANTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACANTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGNTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAANCCTCCACTTATATATCCTCCTTTNAAATTAATCCTTACTAGTTTTCCAGTATTCTNGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCANAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGNGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTANTTNCNAGGATGACTNTCAAATTATTACNCNCACGGCANNNGNTAACCAATGCCTATNGTNTCANAAACNANTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGNAACAGACGAGATAGNTTTNTCTATTNNNAAATAATTAGAACTNNAAACATGTATNGAAAGNAACGATTATTTCTGAATTATTNCAATTATTTGAACAAACAGNNNNGAAGTATACTATCGTCANNTTTTTCTCNNGNTNCANNTACTGCTGATAATGATAGAATAAACGCNATTTATCCNNGTGGTATACCCAAAANNGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGNNAATATAGACANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGAAGATACCATTATTAACAAANTTTTTGAGGTAATTTTCTTTGTTNGACGAATATNTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAANNTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTNAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATANTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCNTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCNTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCNGCGAGTTTAGCCNTTTGATAAATCTCTTCTTGCNTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTNCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGNTTTTTAACGCAATGGTCTTAGATNAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTNAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCNNGGATCTTNTATCAAAGCCNTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGNNNNNATATACAGTAGTCATTGNTTTACCGACACCTGNTTCATGGAACAATNAAAGAGAATGCATACTGTCTAATNCTNNGAAAACTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTNNACGGGCATATTAGTAGTTCTGCGTAAGGCATAANCGATATAGGCNNNNNGTGATTTACTCATTTATNNGNGNTNAGTAATAACTATGTTTTNAAAATCNNNNCAGTAGTTTNNCTAGNCTTNTCTNATGTNNNNTTTCGATACNTTTTGAATNNNAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTNGTATACTCTATTCGAAAACTCTAAGAACTTATTAATNAATTNCGTATCCACTGGATCGTTTNAAATNNTAAATTGAACAGTGTTCACATCCTTNCAAGACGAAGACTTAGTGNNGGACTTAACATGAGACATAAATNAATNCAAANTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCNTTCNNCCAACTANCGCNTACGCATTTTAACAGTCNAANANTTTTAAAGAGACTACAATATANTCTCNTNGTATCGATTNNACCTCTACCGAATAGAGTNGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAANGTTAACATCTTATAATCGCTAATGTATNGATTGNTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTNCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACNGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACANCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTNAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGNGAGTGCTTCTTCTTTANCGGGCTTAAAGACTGCTTTNNGTGCTGAAATAACCACATCTGGANNACTTACTNGCNNAGCCATTTAATTACGGAACTANTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACNAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGNTTTTTAGATCTCATATGTGCTNAAAAGTTTTCCCATACTAATTNGTTACTATTATTTTTCGTATANTTTTTAACAGTTTGAGGNTTTAGANTTTTAGTTACNGAAGTGATATCGAATATTTTATCCNAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCNAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCNTTTCTGTACTCNGATTCAGNTTNTCATCNTTTANNTGATTGATTATTTNAAAGACTAACTTATAANNCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGANNTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTNCAGAACATTGATGAGACAATAATCTCCGCAATACATTNNTCAAATGAATAAGTTTATTAGACACNNGGAAGNTTGNNNNNTTTTGTACCTTTGTACATTTTTGAAATACNGACTNNCNAAAAATACAATATTCATATCCTTGTTCAGATACNNTACCNNNATGTCTANAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTNCAATATTTTATATNAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATANTTTTANTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATNTTTTTCGTACCAACTCNTTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTANAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTANNTCNCGGATTGNAAACAGAAAGAGGATCGTACATCCAAGGTCCNTTTTCTGTAAATAGAATCGTATAATGTNCCTTCAAGAAGATATCNGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTANCCTATACATGATACCGTTTAGCNTGATTTCTGGTGATNCGTCAATCGGAGTATCATCTATNAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATANNCNTATTCTGANNTNNTTCTACATNAAACATCATTGCTCCATTAACGATAACANNNGAATGAACAGCNCTACCCATCACNNTAGTTCCCAATGGATCAANNTGTGTAACTNCAGAACATCTTCCATAGCCTATGTTANGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATNGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGNGTNCATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATNGGAAAGGAGTNGAAATNNCTCGNTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATNCTGAATAGTAAAGNTAGATNNNTCATACTTGTTAGTAGTTAGATATTNNGCAATTGNANTCCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTACGTTTAGGTTTGGTACGTTGATTTCNANNCCCTGCTGATATNAAGTCATCGTCTACAATTTNGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAANNGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTNAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGANTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCNGNCTGAAGTTGACGCATATCNTTTTCAACACTNGACATGAGATCCNTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTNGATTTGGANTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGNNCATACAGTGGCCACAATANGAGGTTGAAGAGGTGTAACCGTTNGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCNTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTNGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATANGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTNCATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCNTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCANNNNNNNNNNNNNNNNNNNCATCCACGNTTTGATAAATCTATCNTTANCTNNTGAAATAACGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGATNACANNTTTTGTAAATGTAANGTANTTAGACGANAGATCTTCGTTNNAAAGTTTTNCATNTATNNNNAATNCATCGGTTGTTAACACCATTCCCGCGTCAGANTGAATANGAGTTTGAATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGATGNAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTNGAGGCCTCCGTAGAACTANGGGANGTAAATANAGATCNAACAACACCTATGATAAAGGAGAATANCGGNTTTATATCCCGTAGTNGNCGTCTATTNNCCCATANNNNTNNGGATNNNNNGANAAAACNNNCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAANTCAACTCNNNAGTATCCATCATCCAAGNAAAACNCGGATACCAGTCTNGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAGTTCANTATCTGAAATAACNNATAGATTTTATNNNNTTAATCNAAAATCTGATCTTGTTCAATGGNGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGNAAATGATTCACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAGCAAACGTGATNAGGATACGCTATTAAAACANTTTACTTATGACTGGNGTTAGAATTTATAGACGNNACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCNAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGANTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATNCTTCTNCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACNNNATGATTGTCTCAAGTCTNCAATCGTTTGTTTNGNNCGATTAGCTNCAGAGTNCAATGCTTGGCTAACTAGCATATTATTATCTTTNGAAATTGTATTCTTCAATGAGGCGTTTNNNATATCNNTGATTTCGTTAGTNATATTACAGTCTGANTNGGTTGTAATGTTATNCAACATATCNNNNNTGGATACGGTNCACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACNAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATANAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAANNCTNAANTAATCAANTTTTNNNNNNNGTTTTTACTACAACTAGTTTTCATCANNGTAGTGACGATGNNTTGTTTAGTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTGGTAACNTTGATAGCCGTAGATCTTTGTTCCNTCGCTAANNNGTTNANNAAATTAATAAAGAATTTGTTGTTTNNATTTATGTCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGNTTATAATCTNATCATTGANNNNTACTCTGTTACCATTGTAATAAATTGGTACTCTATCNNNATCANCGACNNAGTACTGTTCATANATGATGAGATGTTTATATGTTGGCATANNNNNNNNNNNGACGTTTNGTAATGGCAANNNNNNNNNATTAACNNCATAATGTCTAGCAGCANCTGCGATGTTATAAGTGATGTCAAAGCNNGGTTNATCTTNNNNNNTTATATATTGTCTAACACCTATAANATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAANTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCNAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGNAAAAGCTGTGAGTATTAATAATANGGTTAGNTTNCGAACTAATGNNNNTTNGATGATNNNTAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACANTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACNAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCNNNAGGAAATATCATCACAACNNAATGAAGATCTNTTTCCAGNNNNNNNTTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTNGAGAGTTATTGATATCGGAACAACGTCAACAACNAGNAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTNTGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGNAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCNAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCNAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCNTTTTATTAGTGGGCATCTTTTTAGATGGTTTCNTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCNTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGNTTTTTAAGCTGTGGTGTAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTGCTTNNNCCACATAGAATAAANTAGCATTCCGACTGTGNNNATNNTACCNNGTATAAACGCCATAATACTNAATACTTNNCATGNNCGAGTNGGACTGGTAGACTTACTNNAGTCANNAAAGGCGANNATACACGNAAGAATCNNNAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTNCATTTAACTAATNAAAATTTTAAATCGCCGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTAATATCTANTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTNNNCNGCATNTTATAACTAACAGCAGCAACGGCTCGTAANNNNNTATCATTTACTAGACGAAAAGGTGGTNGGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACGTATAATGCNNNATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCNAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACANNATTTTGCCACGCTATCACTATCACCCNGGAGATAATCNTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCANNAGNATATTTTAAATNCTTAATATATTCANGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGNAAGAACTACATGGTTCTCCANGAATTAATACATATTGTTTAGCAAATTCAGGAACTATNAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTNCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTNAAAAAAATGACTTGTGGTCAGACCATAAGTCNTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATNAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTANTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATANTATTATTAATATTGCCAAGTTATCCGATCNNNAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCNGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACNATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCNAAAAAATAAAGTACATGATANGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTNGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACNNGTATTAAATAGAATATTTAANNNNCAAAATCNNNNNNAAGNTTNNNAGACGATCNNCATGCTGNGCNNGCCAGTGTATTANCCCTCATAGTATTAATATAATCCAATGATACNTTTGTGATGTNNGAAATNTTAACCAATTTAGACTGACAGGCANNACACGTCATACANNNATNATCGTCATCGATAANTNTAGTCNTGGGCTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCTGGTATANNGTCTCTATCTTTATNNCAATATAGTGTATCAACATCTTNNTTATTGACCTCNTTTATCTTNGAACATGGAATNGGNACATTTTTGTTAACNGCCACNNNTNCCNTAATTCCAGATGTTGTNAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTNTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTNAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAANNNNTTAGTCTGTACNAAAGTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGGTAACTAATGTCNNGACGTCCATATCTGATTATTATGATGAGGTAAAAAANAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAANGGTAAAAATATGGTAGAACTTGGATCTGGAAACTNTTTTCAAATACCGGATNAGATTCNAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGANGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATNGTATAGGAGATAATNTTTTTATTCCTAGCGTTATAACAAAATCAGGNAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATNGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATNGACACTANNNGACGAGACTANTATGNNNNTGNNNANTANNNNNNNNNNGTTGGTATTGCAGGCNNNAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAANNNTCGATGAGTTAGTTGATGAGATTAATAAATCNNNAACTNTNAAACGAAAAANNAAAAACCAANCAGTATTTGATTTNAGNAGAGAATGNTTGGGATATCCNNNAGCNGANTTTATAACNNNAGTNNNTAACATNNNGTTCNNANNAGNAAATNNTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAANTATATANGGAAACNNCAACCANTTCGTCTCAATCTTTAATACCGTTACCGATGTCNAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCNAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGNAGGTCACCGTANNTCAAATTTATCTATTTTATTNAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTNTTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGNAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATNNNNNCATTCGGATTNCGAGANTNCGTTNCNGATAGACNNNNATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATNAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTNAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGNTTTNCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGNAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGNAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGNTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGANNNNTANATTTNCAATATGTATNNNNNNNNNNNNNNNNNNNNNNNNGATTGCANGAAATNTTGANNNNCAANCGGCCNCTCNTATCGTTTNANAATAATACAGAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACGCATTANCCACGTTCACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTCNNGTTCNNNANNTCATAGGTGGAGNCTTTATCNNNNNACAATCNNNNNNAAAAGTANNNATTAATCTANTAGAAAAGATTACAACATGGCCAAAATTTANGGTTGTTNANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTCATTNGACGTAGTTTATCATACGNTATGCCTCNNNAAGTTGTCTATCTAGTAAANGCGATAATAGANANNGCTAANNNACTTANCGAATCTATTACTGACTTTNATATTGNNNNNTACATTAATGACCTGGTGNNAGCTGAACACNNNAAACNAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACNTTTTACCTCNNATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACNTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATNCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGNGTGGAAAGTTCNNAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTNCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGNAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCNAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATNNGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCNAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTNAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTNNAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGNNNACGTGGAGGAGGTATCAAGTTTGNAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCNNCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCNTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCNTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCNNATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCNTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCNATGCTTCCNNGNNATAGTCTGGAACACTAATGGGTGACGNAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGNGCGGCNGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATNNCATATCATATTNNAAAATCTTGATNGAAGNNCGAATATCTCGTCTGACNNAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTNCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGNTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGNTTTTCTACCTCAGTGGCGAAATCTTTGGNGTGTTTGGTACANTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGNTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCNTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCNAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCNTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAANAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTNAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATNAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCNAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATNGGAAATGTAATAGTAANTTTTTATCATAAAAGTTGTAAAGTAAATAANAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCNGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTNNAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTNTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGANTATTATACTCTGTATTAGTTCNGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGNAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATANNCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATNAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAANTTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCNTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTNAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCNTAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGNAGTTANTTACGTTGAACAAGTNCATGGNAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTNGAGGATGTGATTCCATAGGCAGTCNNNAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACANTTTCTTNNNATTAACGAGAATGGCGTTTNATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGANGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACNGAAATACTATATCNNNCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGANACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATNAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAANNTTTTTTATAGTATGAAGGNNNNGATGNNNNNNNNNATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATNAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTANTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTNAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATNAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTNGATAATCCATTTATNTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTANNNGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTNNNNNNAAATACNTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATANGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTNAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATANCCAATAGAATAGTATTCTCAGAGTTGACGAATANTNGTNNNGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTNNGACGATGAATNCGGTAAATGGNNGACGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCGATTTTGTAGTAGATGATNCGNAACAATCTCAGATATGGGAAATTTCAGGAGCAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNANGAAATAAATCATATNNAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTNAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCNTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCNAGACTACATTNNNGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATANNTTTTTTTAAGCACGAAATNAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTANGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCNNAAAGNAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGNGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTANTTTTTTCTGTAATAGTTANAAANNACNNNCGATGGTCTATCTACCAGATTATNNNNTGTTATAAGGTACTTTNNTCNTAATAAACTAGAGTATGAGTAAGATAGTGNTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTNAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATNAAAATGTNCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATANNTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGNAACATACGATAAAGNAAAAGATTGTTGGACATTNGATAATGGTCACTTGTTACCACATAATTATATAATGNNTAAATGCGAACCGTTTNAACATAGATATCCATTNNNNAAAANACAGTACACGAATGATTTTCNNNAGTATTTNNNAAGNTTTATANNNAGTTNATAGAACAAAATACATNANTTTGTNAAAATAAATCACNTTTTATACTAATATGNNACAATTANCAATACTTTTGTTACTANNNNCNNTAGTATACGCTACACCTNNTCCTCNGANATCTNAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATNAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTNNANNCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCNAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTNNNTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTNTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACNATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGNTTTATACAAATCCATTAATGTNGAATATCGATTCTTNGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAANAATAATAGACTACCAGNAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGNAATATAGTCTTGGATCAAATAGATAAGAATAAANTATATCTAGTGGATTACGGATTGGTTTCTAAANTCATGTCTAACGGCGAACATGNTCCNNNNATAAGAAANCCAAATNAAATNGATNNNNGTACTCNAGAATTTACACCTATAGATTCGCATNAANNATACNNNNNNNNNAGACGTGGTGATCTAGAAACANNNNGATATTGTANGANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAATTGCNNNAATATATTANNATGGTANNNNNNNNNACATATTTTGAGGAACCNAATTACGACNANNTTNNNNNNNTNTTNNNNNNNNGANNTNNNNNAAATTTTTNTNGATNNAANNNNNNNAAAAATAACTNNGTTATTATCANNCTCGTGAGNANAATNGAAACANNNNGNNGNNNNACGNNCACGCTTTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCATCGACNGTTGCCNNNNNNGTCANGAAATATTCTGTTGTGTCAGTTTATAATNAAAAGTATAACATTGTAAAAAACAAANATATGTGGTGTAACAGTCAAGNGAACAAGAGATATATTNGAGNNNNNNNNNNNNNGTNTGAATGCAATGAATATCTACAAATTGGAGATNCAATCCATGATCTAGAAGGAAATCAAATNTNTATTGTCACATATCGCCACAAAAACNACNATGNTCNAAGTGGAANNNNNNACGAGAGTCTAGANNTGTGNTTGGAANGAGTANGGATNNNTCATCACGTACTTGAAACAGGAANNNNGGTATATGGAAAAGTNCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGNGNCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCNNTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGNGAAAGACACTGAATCAATNGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATNGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGANTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACNTTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATNNAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGNTTTTTGTATCAAAGACATTAATACTTTAATGAGATACNGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATNCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAATACTTNNNNGAATGATANNNTCNCGTGTCCTANNNNNNNNNNNNNNNNNNNNCNNTTAGAACACNGATCNTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCCCAACANNTGTACGATCTAACGAAGAATTTGATCCAGTNGATGATGGTNCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATNAGCTAGAATCAATTAGATGTCTTCTTCAGTNGATGTTGATATCTACGATGCCGTTAGAGCANTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTNGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACANTTAATGGTATAATGATGAATGAATTCGATACNGTATGNGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTNTAGCTAATNNGAGATATNGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATNAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGNTGCATCCTATTCGAATAATGAGTACANNCCGTTTAATAAACTGAGTGTNAAACTCNATATNGANNGAGTAGATAATATAGNAAATNNNNATACTGATGATAATAATNAANNNGTGTTANNNNNTNAANAGTNNACNNTTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCANAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCNAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACNTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCNATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGANNNAACATNGGGNTTAAAAATANGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACNGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACNCAACAAACACGTCTTGGATCATCNCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCNAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCNGGAGACATAAAATTTGAGGAGNATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNCTTAACAATTNGTTCTGATCTACAGACANNNNTTAATAAATCANCTTATTTTNCCAANATATTAAAANNNNNNNACNNCACNNNTNNNNNNNNATTGTGCGNCTTTCAAGATGATGNNNNATATAGGGTNNTACAGTTTTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAAATTATTTGNNTAGAATATTACGNNTATAATTGTTTNGAAATTTATAGAATAACNNNTATTAATACATTATNGTATATCTACAACGNTATNAGNNNCTTCATATTNGATAATATTACTANTAATATNNNNGGATNCAGANTTNNNNNNNTTGCCTAAATACATNNTTATAGNNTTACNNNGACAATCACCTAAATGTTTTNNACGNAGATAANNNGGTAAAGATTATNNNNACTTNTANNNCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATANNTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATNGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATANAGATGTAGAAGATATCATGAATGAAATAGATAGAGANAAAGAAGAAATACTNAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTANAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCNCGATGTAGGAATATAGANCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGNTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATNGATCATAAATCACNCAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCNTTGACTATCAACAACTGGACACGAGAANNTGGTATAAANNATTTGGCTATTNCAGATCTGNNTNNAATTGGAGAAACCGATGATTATATGTTCNTCATTATAANNAATTTGGGAAGAGNANTCGCCCCAAAGGATNGTGAATCAGNNTTCGAAGCATGTGTCACTATGATNAACACGTTNGAGTTTATACACTCTCAAGGATTTACTCATGGNAAAATNGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGANGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTNCATGGNNAAACGAAAGTAGTATNNAAGTAATAAAACNNAAAAAAGAATATAAACAATTTATAGCTACNTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAANTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATNNTANNCNNNTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCNAATATTAATATTAGACTATCTCTANCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCANCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATNNCNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNNNCTTTAAAGCNNAATNGTTGATGCCATTCGAAANNGAATTTACCAGTGATTATCCCNNNNACGTATCTCCNNNNNAAATNGTAGNNGNNNGNATNATGTCTATTTNCGGCGAGCCANTTAATCACGCATCTNNNNNNNAATCATTCNGNAACNNNNCAATCATAGAACTGCCATATGTTGGNGATNCTAGTATGATGGNCATTCTTCCNAACAAGATTGATGGATTAGAATCCANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATAATCTTGTNNATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGNGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGANGNGTATACAGAAGCAGCTGCAGCAACTTCNGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCNTTTCGTTGGTAGATATTGCTNTNCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACANNTTTTTTTAAAAATAGNAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTNGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTNGATNTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGNNNNNNNNANNNNNNNNNNNNNNNNTTTAAAGATGATGNGGAATCAGTNNNNATCGACGTNCGTGAGCTGGNNAAAAATATGCCGTGGGATAATGTTNAGGATTGTACAGAGATCATCCGTTGTTATANANNGGATGAGCNAAAANNNATCNNNNAGATTTCGGCCATCATTGGANTTTNTNNATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACNTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATANTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGANNATATATATATATATATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACNTCAATAGGTNGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTNGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACNNTATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGANCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGNTCTCNGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATNGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTNTACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTNAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATNAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTTTAGATANCNNTAGATCACTTGATGGGTANGATATTAATTGTTACTTNNNNNGACGTACACCACTTCATTGCGCTATACAATATNNNNNNACNCAGATTGCTGANTACTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTGATTAGTCGTCTACCGCCTAAAAGNGTNATATGCTCACTGACTAACCATATAATAGATTATGTTCNTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTANNAAGTACGTACTGTTACTGGACCCATCNNNNTATTATAGANTCAGNAATGTTATCGNNNACAAATTAGACCAATACAATAATCGTTATAATATNTTCGAACACGATANNGACGTTAANNNNNNNTATGGCAAAGTCNTACATGANCTNGATACATATATCNAGGNNGTNNAAGTATTAAAATCTACTTCCATCNNNAATAATATAACACTATACGACACNNNTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAANCTNATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTANAGAAATATACTTTAACTNATATAGTCCTNNAGNATATGATCTCATCTCNNTCTCAATCATCTTATTTGAGTCGTATTNCTAATGAGANNNTACTCGAAATATTATATAAANTCGACATGTACGATTTANNNNNNNNNNNNNNNNNNNATATNNGAGAGAATGATATCACAGAGTATCATATNNAGAATACGANGTCTGTTTCTNNANNGACATGAATAATGANNACACATNNAACNNNNTTTTTAATCTTNGATATAACACTAATTACATCNAGATTATATATTNAAATCGTAATTTGAGTTGTCTGATCNNCATGNNNNNNNNAAANNATATACNNAACATNNGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNATATAGAGAATATGAATGAGAATACANCCGATGATNAGNAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACNAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGNAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTANAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTNAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCNAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCNAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATNGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGNAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGNTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATNCATAAAAATGACACTGTTGACAATAACACNATGGTTGATNANGNGACANCTAACAATAACACATTACATGGTAATATAGGANTTTTNGAAANAAATAATTGTTATANNNTTTCNGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACANGAACNAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTNATGGCATCCGTTATTCCTGCAGTTAANGAANTTAACAATACGTTGATGAAAATTGGTGTNAAAGATNATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTNTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTANNNACAATAGTGTTTCGACNNCTAACAGCAGNAAAAGACGAGATCTGAATGATGAGTTTGAATTTTNCACTTNCNAGGAATTAGATTGTCTTTACGAATCNTATGGTGTAAANNATGATATAAGTCATTGTTTTGCATCACCTAGACNNNGACGATCNGACGACNAAANNNNGTACATGGACNNGNAATTATTCNACNNCGNNNANNNNNANTTNGGAATAGACAGTGTTATTNCTNGANGTACAACCCATTTNCAAGTANGTGCATCTGGTGCNNNTGGTGGTGTTGNAGGAGATAGNTTNNCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGNAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCNAAAGCTTTCTAATGTTNGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCNAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTNCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTNAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATNAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTNAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCNGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATNTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTNACAAAATCCATTTAGACAAGAAGGGACATATAAGCNACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAANCTATGATATTGGAAGATGTATNATNGTGTAGTTCTAGAACTAGNAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTNTTACAGCAACCTCCTTNNACATTCGAATTCATTCNTGACAATTCTAACGAATATGTGGATANAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGNCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACNAAGATATAAAAGACATTATAGAATCCGAAGAANGTAAGAGATNNNNTATAATAGATGTTANNAACAATCTTGTTNNAAAGTACTATTNTATTGATAATTATCNNTGTNATACTTTAGATGATTATATATACANCTCTGNAGAATATAACAANNNCTNTNTGTTAGNAAACGATACTTNTATANGCNNNNACTATCNTGAATCATCAGNNGTANNNGTTNTATCATNTTATGAAANGACTANAATCTCCTTNGATACNAAAGACGCCAAAGATGCTATAGAAGATGTGANNNTAGCNAGTGCNGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATNAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGANNTTTTTTAAATGAGTATCGGTAGTTACANNNTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTANCNNGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGNTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGNNCACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGNGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAANGGTACTTATNCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTNATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCNNGATTTTCGCATTGACTTTACACAGACATGAACATNCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAANGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTNCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCNAAAACTCACTTTTGANTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATNAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATNNAANTGATATAACNAATACAGCAGATATATTGCTNGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGNAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATNAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGNNAGTTAAGTNNTNNGTTAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGNNNNAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATNAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGNACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTNGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATNTTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTNCATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCNGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAANNAAAGTGTGGAATAGGATACGGAGTATCCGGNTACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTNCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTANNAACTTCAGGATTCTTTACNGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTNGNNNNNNNNNNNNNNAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTNTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATNCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGNNAGNTNCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGANNTATCCGAAGAAGTTGTNAAAGGAGATCCCACCACTTATTACACTATCGTCNGTGCGGGTCTTNNNATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACANTGTGAATACTAGATTGTCCAGCGTGTCACCNGGACAAGGTAAGGANNCTNCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATNCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGNTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGNNCGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCNNCGGATCGGCATCTGAAGGTGCAACCGATGATACTTNACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGNAAATGGATGAGTTNGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACNAAAATATTTAACTACATTCACAAAAAGTTANNNCTCGTTACTTCTTCNTTCTGTTTCAATATGTGATACGATATGATCACTATTCNTNTTCTCTTGGTCTCATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNN +>Monkeypox/PT0008/2022|sampling_date_20220515 +TAATTAATTTAATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTTGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTANTAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTTGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGAGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTNNANNNNNNNNNNNNNNNNNNGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGAGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTAAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAAAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATTAAATTAATTA +>MPXV-UK_P2 | MT903344.1 +TAATTAATTTAATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAANNNNNNNNNNTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATTAAATTAATTA +>KJ642617 +CGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATGATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATCGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCATACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAGATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTCGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTCGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACGCATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCGTCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAAGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACCGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCCAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACGAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGCATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGATGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATATATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGATGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGCGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGTCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACCCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAGATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGGCTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTCTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTACGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCRTCATCATSATCATCATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCGTTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACGAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGCGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACCGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGTCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCATGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAAATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCTATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCATGTAGGTCTTATCACGTGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAAGATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGGAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAGAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATCATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCG +>ON676708 +ATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATTATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGTTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTTTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGNNNNATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATNNNAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAAT +>ON674051 +TATTATATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATANTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTATAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATTAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTTGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATTAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATTACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTTCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACAAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATAAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTTATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAAACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTTGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTTAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTAATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTAAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAAAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGAACGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAAATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATTTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATAGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAAACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCNNNTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGCGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATTATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTTTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCAAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTTAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACAATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTTATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAATGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATTACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGAAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTTCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACACCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGANNATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTTGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTTATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAANTATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATATAATA +>MT903339 +CGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATGAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGGAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGGATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCGATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATCAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATCGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGGCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACGATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCGAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTCGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAGAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATGAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCGAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGGAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTGAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCGATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTCAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTCTCAAATATTTTTTTAGCCTCGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCAAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTGACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAGAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGGACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTTGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCGATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTCTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATCAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTCGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAGATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATGAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTGAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAGACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTCGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACGACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTCGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTCGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATGATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCGAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACGATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTGCCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATCTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGCGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCGAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCGAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAGAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTCGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCAATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAGATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATCATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCAGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGGGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTGAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATCTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTCGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTCTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGGGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATGATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACAAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTGACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATCCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATGAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTCAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGATTTCATGGCTGTCGATGAGCAGTTTCACGACGACCTCGATCTTTGGTCATTATCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGATAATATTGATCAGTATATAGTAGATAGACTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTGATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATCGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATCCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTCCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTCATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCG +>ON843165 +TAATTAATTTAATTTTACTATTTTATTTAGTGTCTAGAAAAAAATGTGTGACCCACGACCGTAGGAAACTCTAGAGGGTAAGAAAAATCAATCGTTTATAGAGACCATCAGAAAGAGGTTTAATATTTTTGTGAGACCTATCGAAGAGAGAAAGGATAAAAACTTTTTACGACTCCATCAGAAAGAGGTTTAATATTTTTGTGAGACCCATCGAAGAGAGAAAGAGATGGTTAGTCAAGATATTTTTCTTAGTACAAAAGTCAATGTTTTAAAATATATGGACGAGAATTAATTTGTCTGTATAAAAACTTGTGTGAAATTATGTACTAGAGAAAAAACGTGAGCAGTGTCCCCTACATGGATTTTACAGATCATTTATATTCCAAAAATATTAACTATATACGTTTATTATATGATGTTAACGTGTAAATTATAAACATTATTTTATGATGCAATTGTCTGACAACCTAGATTGGTATAAGGATGTTGATAAGCTCTACGAGAATATATTGTTGGACGTTATCGTTTACGAAATAGTTGAGACATCAGAAAGAGGTTTAATATTTTTGTGAGACCATCGAAGAGAGAAAGAGAATAAAAATATTTTTTTTTTTTTTGTAAAACTTTTTTATGAGACCAAGAGAATACGAATAGTGATCATATCGTATCACATATTGAAACAGAAAGAAGAAGTAACGAGAGGTAACTTTTTGTGAATGTAGTTAAATATTTTTGTTTTGCAAACCGGAATATAGTGCCCGGTCTTTTTTAATTCGTGGTGCGGTGTCTGAATCGTTCGATTAACCCAACTCATCCATTTTCAGATGAATAGAGTTATCGATTCAGACACATGCTTTGAGTTTTGTTGAATCGATGAGTGAAGTATCATCGGTTGCACCTTCAGATGCCGATCCGTCGACATACTTGAATCCATCCTTGACTTCAAGTTCAGATGATTCCTCACACATGTCTCCGATACGTACGCTAAACTCTAGGTTCTTGACACATTTTGTATCAACGATCGTTGAACCGATGATATCTTTGTAACTCACTTTCTTATGTGAGATGTTAGACCCAAGTACTGGATGGGTCTTGATGTCACTGTCTTTCTCTTCTTCGCTACATCTGATGTCGATAGACATCTCACAGTCTTTGATCATAGCCAGAGCTTCTTCACGCGTGATCGCGGGAGAGTCCTTACCTTGTCCCGGTGACACGCTGGACAATCTAGTATTCACAGTGTTTCCATCAGAGGATTCGGAGATGGATAAAATCTTTGGGCATTTGGTGAATCCAAAGTTCATGTTAAGACCCGCACCGACGATAGTGTAATAAGTGGTGGGATCTCCTTTTACAACTTCTTCGGATACCTCATCATCTTCGGTCTCTGTAACTTCCGTTACGGATTGACAAATCTTATCATTGGTCGGTGTTTGGTCTTGCTTTGTGACTTTGATAATAACATCGATTCCCATATGATGTTTGTTTTCTTCTTCAGTACACGAGGATGAAGATTGTTGAAGACTAGTAGGCATAGCAGCTGCCACTAGGCACATGCATGCCAGGACAATATATTGTTTCATGATTGCTATTGATTGATTACTGTTCTAGATGATTCTACTTTCTTACCATATAATAAATTAGAATATATTTTCTACTTTTACGAGAAATTAATTATTGTATTTATTATTTATAGGTAAAAAAACTTACTATAAGTGGGTGGGATTCTGGGAATTAGTGATCAGTTTATGTATATCGCAACTAGCGGGCATATGGCTATTGACATCGAGAACATTACCCATATGATAAGAGATTGTATCATTTTCGTAGTCTTGAGTATTGGTATTACTATATAGTATGTAGATGTCGACGCTAGATAGACAGTCGCCCACTAGAGTTACCGTCTCTGAATGCGGCATGATAGTATCATTCTTTGTTTTCGTTAACTGTTTGGAAGATGAATCTTTGTTGTTACATTTAATCTCGAAATTCAGAGTACATATCTTTGAAGTATTCTGATATCTATTTTCTCCTGTAAAGAATCCTGAAGTTGCTACATTATTAAGGACAGAGAAGTATTCTGCACGAAAGACTGGATCACAATCTTTATGATTCATGGTAATAGTTAGTTCCGACGTTGAGATGGATTCGCTGAGACCGGTAGTGGTCGTCCGAGTACACGATGTGTCGTTGACTGGATACAGGTTAATTTCCACATCGATATAGTTAAATGTATTGCTGGTTACGACGGGTTCGCATTTATCTGTGGAAGAGACGGTGTGAGAATATGTTCCGGGACCACACGGAGAACAGATGACGTCTCCGGTAGACGTGTATCCGGATACTCCGTATCCTATTCCACACTTTGTTTTAGAAATACATGTTCTACACCCTGATGCTCCTTTGAGAAGACAATAATATCCTGGAGAGCATTCACAGATTCTATTGTGAGTCGTGTTACACGATCGCGTCTCTACCTGATTACTATCACATCTTCCGTTACAACTTAGACAAGCCTGTAAATGATTATTGTGAGATGTAAAGGTATCCGAACCACACGGTGTACATTGTGTATTAGTCTTGCTATCACATAATCTGAAAGCGTAAGTTCCCGGAGGACACGATAGACAACATAGATTACGGCTTCTGTATTCGTTGTCTTTACACTTTCCATTGGATGGTGCATGTGGTGCTATATCTCTTCCGTTTATTATTATACATGAGAGAAACAATATATACGAGTATAATACGGACCTCATGATTTAATAATGTAGTAATCGTCGTCTTGTTACTGTTTGTTTCCTACTTCTCCAATCATATAGATTATTTTTTAAATATTTTCTTTCTATCATGGATAATATTTGTAATGGTTCTTTCCGTACAACATACTGTTTAGATGGTAGTCGCTTAGCTTGGTTATGATATTGCGCATAATTTCCGGAGGCAAATACGATAGTCTAGATTGACTATCGATGGTAGACTCTAATTTATTGAGTGCTTTGTCGACGAGTTTACTTTTATGCTCCATCGATAGATGACACTGTTCTATGAGATCGTCGTACATGGGAAATGAAATGCGTTTGTCTGAATGTATGGCTTCGAGATATGTGTGATACCGAATGTCTTCTGTTCTCAATACCGTATACAAGTCGGTGTCTGAGATTCGAATCTCTTTGAGGAGACTTATGTCACGACTACATTTTTCGATGATGGAATCTATCTTATCGAATGATATATTTTTCATAAATACACTTTTATAGTCCTCGTTTAAACAGAATTTAGTATGTAGTTCCGCAAATGACTCGTCCCTTAATAGGCAGTAGGCTATTATCTTCTTTACGTAGTGATCGTCGTAGGGAGAGAACTCCGACATCTTGTAGAACAACGATTTAATCATAGGTAGAGATACTTTCAGTCTGTGGTGGATAATGTCATTAACGACATCCGCCTTGTATATAATGTTTCTGTTTTCAAACACCAAGTCGAATACTGTCTTATCGTCTTTAGTCGGAAGGTTGATGTCGTATCCAATGTATACGAGGTATGAGGCAACATTGTTATTGCAATTCTGGAAGGCGGTATGAAGAGGAGTCATTGTATTATAGTATTCGTCTTTCTGAATGTCGAATCTATCTAGTAGATACCGTAGTATATTGAGAGAGCGACTTCCATATCCTTGATTATGTTTTATGAATAGATAAAGTAGATGTTGTCCTTCTTCCTTTTGTAATTTCCCGTATTTTTGTTCGTGCCAATTGAGTAACATTATGAGAATATGACCTGTTGCACAATCGTTCTTTATGTATTCCATGATGGGTGTACAATTAAGATTATTACGTATCCTCGTATCGGCTCCTCGAGATAAAAGAGCATACACCACACGAGGACTATGTTTGGTATACTGTTGAAGGTAAGTGTGTAACGGCGTATTTCCGATTTTCGTAACCGCGTTAATGTTTGCTCCATGATCTATTATCGCGTAGATGAATCGCTTCTCAGCTCGCATCTTAGTGTGACTCTTTGACTTGTAATAATTGCTTTCGTGGAACGCGGATATGTGTTTACAGTAGTAATGAAGAGAAGTGAGTCCATCCTCATCGACGCAATTAGGGTCAGATCCTTTAGTCAATAATTTGTACAGAACGTAATAGTTTAAGCTCCCATTGAATTTATATCTAAGATAACACAGCAATAGATCGGATGATTTACTAAAGTCATCAATGGGGTCCGTTAGTATATCAAAGATCTTGTTATCGATTGATAGTGAATGAATCAGATAGTGGTGTAGAGGAATATGTCCTTTTTTATCCTTGCTATCAAAGTTACGCATGCCGTGGCGTAACAATATCTTTAATACAGATGGATTAAATCGTGTATTCATCGTATAGCAATGTAATGGAGAGTTACCACATTTTAGTCGTTTATTCAGATCGCAGTGTTTAATAACTAATTTAAACAGATGAGATGATATATCCACATCAAAGAATGCGAGATACATATGACAGACATTATTGACAGAAATGTGACCTTCATTATCACCGTCGTCCATAAATGCGTTAGGTACGTACCACATACTATCGTTAACGATGCGCACAATCTCGTCCATTTCATCCATCTTCATAATGATTTACTTTTTCATAATTAGAGAAAAAGATCAAGGTATAAAAATTAGAAGTGTTAGACTATAAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTTAACTAACTTATGACTATTAACTCATTTCAAGAAAGGTGGGTGGATAGAACTCTATATGACAGCTTGTGAAACAATTAGATCCCTAATTTCTAATGGAAGTTTTGATAGGAGATTGTCATCAGTTGATACATTGTTTATTATCTCATCTATTAGAGCACGTCTGTTTAGAGCTTTAGTGACCTGCTCGGTTACTTCTGTGTAAATCTTGAATCCTTTAGTGATACACTGTGTCAAAACTGGATGTTTAGAATACCTATGTAGAATATGGGAAGCATGCTTGTTTTTGTCTCTATTATAGATTAACTCATACATGGTTGTATTATGAATTTTCATCTGCCTAATGTACTCCAATTCTTGTTTACAATCAATTATATAATCAAAGAGTGATGATGCATACACATTACAAAGTGAATAATCTACCATCATAAAATACTTGATACAGAGCTTTATCACATCATGGTTTTCAATTGTATTATTAAGTATAGCTAATTTTATACAGTCAATAGACAATGGTTCTCTAAGCAATATTTCTAATATTTTAAGATGTGCTTCCCTACGGGCGATGACAGATCCCCTATCCACGGCCACGTCAAGACATGTATATCCATTACTCATTACTGCGTTGACATTTGCTCCATTTTCTAATAGCCATGATACTAAATCTATATAACCTGCATAGATAGCGCGATAAAGCAAGGTCCTTCCACCAGCATCTAGTTGATTGATATCTTCAATATATGGGATACAAAGCTTATAAATTTCTAATACTGTGGGTTCATCTACAAGGAATCCCCTAGTATACTGAATTATTTTATATAGATCTAATTTAACATCATTTTCATCTGGGATACCACAATTCAAAATAAACTCAACAACACTACTTTCCTTTTTACATATTCCCCTAAAATAGGCATTCAAGCATTCTATTTTATATATTACAGCCCCATGATCTACCATAAGATCAACAATGTCTATTTCTACATATGCATTAGATAGATAGTAAAGTAAGAGATCTTGCACAGAATTACAATTCTTAATAATTATAGAGAAAATATCTTCCATATAATTCTTTGACACTAATGCAGATATAATATCTTTATATGTAATATATGCAAACAGTCTATCTACTATATACTGATCAATATTATCTCTATGAATCCTAAAATAATCATACAGAACATCTACAGGATCACAAATTGGTTCAAGGAGAAATCTATCAAATATTTTCCTGTCAACAACTGGTTCTAGAACATAACAGTCAACACCTAATCCATGTTTTTTATAATCATCTACCAAAGATAATGACCAAAGATCGAGGTCGTCGTGAAACTGCTCATCGACAGCCATGAAATCTACCGACTCCATGGTGCGAATCGCACTGTCTTATTCGCCATTGATTTTCATTTTTTATAATTATGTACATGTTTTCCTTCTATTCTCAAGAGTCTACAAAAATATATTTTTTCGATATCTAAGTACTAAGTTTTTTTACTGTTTTTGTTACTGTCTTCCATTCTTCTAACTAAAGATCTGAGATAAATTATACAATCTTCGCTATCGAACCATTTTTGTAGTCTAAAGCCTGAAGTAATTAACCAACTGTTTTTATTAGTGGCTTTTTTCGATCTATCCTCGTCCTCTCATCATCCTTATATTATTATCATTATTATCATAGTCTATTAAACACAAATCATCTACGTTTATAACAACATTCTCATTATTAATTAGTTCTGTAGAATATCTTTAATAATTTGGCTATACATCTGTTCAATACTATCTATTGATGATTTCTTTTTTAAGACTTAAACTAGTTATGGTAATGACGATGAAATCGAGTAGTAACTTCTAATAAAGACTTGATATCATTATCATATGTTTGATCGTCATAGTTAATAGTGTGGCTAAATGGTACTGTTAATAAGTTTATAGACAATATCATAGTATTTTCTTTCCAGAATTAGATTATTTTTTTAAATACTGATCCTCACAATTCCGTGATGTAGCAGTAGTTGGTGCATGGTCTATATCGTTAAAATGTATCATATATAATAGTTTTCTGACGTGGAGTACAGAATTTTCGATTAATGAGTTCATGGTAAGGAAGGGCAAATGCCTGTATATAATATACATAAGTTAATAGTTTTTTATCATATTTTCTAATACCATAATAAAAATTATCATTATTGCGTTTGGTAGTTCTGCCCTATCATCTATATCACTGTCACTCTCGCTCTCACTATATCTTCTAAAATTACAAACAACTGGATATTCGATAACAGCATTTGTGTAGTTTTTGTCTTTTACAGTATATACGTTATTGTCAAAATCTAAACAAATATTAGCATAATACATCTATCTATAAGATCAGGATCCATGTTCGAGCATACTAGCCATGTATATTTGTAACTTCGTCGTACAGCGTTAGATCAATAGAATAAACAATCGTGTGACGCAACTTTTTTACGATCTAGTTGTATGAGTTTATCGTTTACATAAGCAATTAACGGCTTTAACAGATGATCTGAGTAATAATATACCTCTGTTATACGTTTAATGTTCACGGTCTTAGTATTTTTAGATATCAATTGTGATTTACACCATATTCGACTCCCTTGTGTGTAACGTTAGAAATTCTAAATCTATATTATCTATTACAGCGTAAAACACATTCAATATTGTATTGTTATTTTTATATTATTTACACAATTAACAATGTATTATTAGTTTATATTACTGAATTAATAATATAAAATTCCCAATCTTGTCATAAACACAAAATCCATTAAAAATGTCGATAAAATATCTGATGTTGTTGTTCGCTGCTATGATAATCAGATCATTAGCCGATAGTGGTAATGCTATCGAAACAACATCGCCAGAAATTACAAACGCTACAACAGATATTCCAGCTATCAGATTATGTGGTCCAGAGGGAGATGGATATTGTTTACACGGTGACTGTATCCACGCTAGAGATATTGACGGTATGTATTGTAGATGCTCTCATGGTTATACAGGTATTAGATGTCAGCATGTAGTATTAGTAGACTATCAACGTTCAGGAAAACCAGACACTACAACATCATATATCCCATCTCTAGGTATTGTGCTTGTATTAGTAGGCATTATTATTACGTGTTGTCTATTATCTGTTTATATGTTCACTCGAAGAACTAAACTACCTATACAAGATATGGTTGTGTTATATTTTTTATAAAATTTTTTTATGAGTATTTTTACAAAAATGTATATGTATAAAAAAAATACTAAGTATACGATGTATCCTGTATTATTTGTATTTATCTAAACAATACTTCTGCCTCTAGATGGGATACAAAAATTTTTTATTTCAGCATATTAAAGTAAAATCTAGTTACCTTGAAAATGAATACAGTGGGTGGTTCCGTATCACCAGTAAGAACATAATAGTCGAATACAGTATCCGATTGAGATTTTGCATACAATACTAGTCTAGAAAGAAATTTGTAATCATCCTCTGTGACAGGAGTCCATATATCTGTATCATCGTCTAGTTTTTATCAGTGTCCTATGCTATATTCCTGTTATCATCATTAGTTAATGAAAATAACTCTCGTGCTTCAGAAAAGTCAAATATTGTATCCATACATATATCTCCAAAACTATCACTTATACGTTTATCTTTAACGAACATATACCTAGATGGTTATTTACTAACAGACATTTTTTCAAGATCTATTGACAATAACTCCTATAGTTTCCACATCAACCAAGTAATGATCATCTATTGTTATATAACAATAACATAACTCTTTTCCATTTTTATCAGTATCTATATCAACGTCGTTGTAGTGAATAGTAGTCATTGATCTATTATATGAAACGGATATGTCTAGTTAATATTTTCTTTGATTTAAAGTCTATAGTCTTTACAAACATAATATCCTTATCCGACTTTATATTTCCTGTAGGGTGGCATAATTTTATTCTGCCTCCACAATCAGTGTTTCCAAATATATTACTAGACAATATTCCATATAGTTATTAGTTAAGGGACCCAATTAGAACACGTACGCGCTTATTCATCATTTGGATCGTATTTCATAAAAGTTATTATGTTATAGATGTCAACACATTCTACATTTTTTTAATTGTCTATATAGTATTTTTCTGATATTTTCTATAATATCAGAATTGTCTTCCATAGGAAGTTGTATACTATTCGGAATCAGTTACATGTTTAAATAATTCTCTGATGTCATTCCTTATACAATCAAATTCATTATTAAACAGTTTAATAGTCTGTAGACCTTTATCGTCGTACATATCCATTGTCTTATTAGTTACGCTTATTTTTATGGGTTTTACGTTGCTTTATTATATTTTATAATAATGATTGTTTGACAATGTCGTAGTATAGATATATTATTAGAGGAGGTATAATTATAAAAAGTTTCTGAGTACGATGTTATAAGAGGAGAGGACACATTAACATCATACATCAATTAACTACATTCTTATAACATTGTAATCAAAAGAATTGCAATTTTGATGTATAACAACTGTCAATGGAATTGTATATTACAAATTACGGTATGTTGTAACAACAAATACCGATCGGTAATTGTCTCTGCCGCTGTAATAGAATTAATTATATATCTATTACACCGGCCTTGTATCATAATAAAGTTGTGGTAGTATGATCTCCATATTTATAATTTAGTACTTTGTATTTAGTTTTTTTGGAATCATAAAAAAAGTTTTACTAATTTAAAATTTAAAAAGTATTTACATTTTTCACTGTTTAGTCGCGGATATGGAATTCGATCCTGTCAAAATCAATACATCATCTATAGATCATGTAACAATATTACAATACATAGATGAACCAAATGATATAAGACTAACAGTATGCATTATCCGAAATGTTAATAACATTACATATTATATCAATATCACAAAAATAAATCCACATTTGGCTAATCGATTTCGGGCTTGGAAAAAACGTATCGCCGGAAGGGACTATATGACTAACTTATCTAGAGATACAGGAATACAACAATCAAAACTTACTGAAACTATACGTAACTGTCAAAAAAATAAAAACATATATGGTCTATATATACACTACAATTTAGTTATTAATGTGGTTATTGATTGGATAACCGATGTGATTGTTCAATCAATATTAAGAGGGTTGGTAAATTGGTACATAGCTAATAATACATATACTCCAAATACACCCAATAATACTACAACCATTTCTGAGTTGGATATCATCAAAATACTGGATAAATACGAGGACATGTATAGAGTAAGTAAAGAAAAAGAATGTGGAATTTGCTATGAAGTTGTTTACTCAAAACGATTAGAAAACGATAGATACTTTGGTTTATTGGATTCGTGTAATCATATATTTTGCATAACATGTATCAATATATGGCATAGAACACGAAGAGAAACCGGTGCGTCAGATAATTGTCCTATATGCCGTACACGTTTTAAAAAAATAACAATGAGCAAGTTCTATAAGCTAGTTAACTAATAAATAAAAAGTTTAATTATCGACGATATATGTCGTTATTTTTCTCTCATATGAAAGATTAATTTGATTCTAATATAATCTTCAGTATTGGATGAATCTCAATTCAAATTAATTCCATTAGATTAGATTAGATTAGATCATAAATAAAAATAGTAGCACGCACTACTTCAGCCAAATATTCTTTTTTGAAACGCCATCTAGCGTAATGAGAACACAAGTGAACCTATAATGAGCAAATTTATTAGTATCGGTTACATGAAGGACTTTACGTAGAGTGGTGATTCCTCCATCTGTGGTACGAACGGTTTCATCTTCTTTGATGCCACCACCCAGATGTTCTATAAACTTGGTATCCTCGTCCGATTTCATATCATTTGCCAACCAATACATATAGCTAAACCCAGGCATACGTTCCACACATCCGGAACAATGAAATTCTCCAGAAGATGTTACAATGGCTAGATTTGGACATTTGGTTTCAACCGCGTTAACATATGAGTGAACACACCCATACATGAAAGCGATGAGAAATAGGATTCTCATCTTGCCAAAATATCACTATAAAAAATTTATTTATCAATTTTAAAGGTATAAAAAAATACTTATTGTTGCTCGAATATTTTGTATTTGATGGTATACGGAAGATTAGAAATGTAGGTATTATCATCAACTGATTTTATGATGGTTTTATGAATTTTATTATGCTTCACTATTGCATCGGAAATAATATCATATGCTTCCACGTATATTTTATTTTGTTTTGACTCATAATACGCACGTAATTCTGGATTATTGGCATATCGATGAATAATTTTAGCTCCATGCTCAGTAAATATTAATGAGAACATAGTGTTGCCTCCTACCATTATTTTTTTCATCTCATTCAATTCTTGATTGCAGAGATCTATATAATCATTATAGCGTTGACTTATGGACTCTGGAATCTTAGACGATGTACAGTCATCTATAATCATGGTATATTTAATACATTGTTTTATAGCATAGGCATTATCTACGATATTAGATACTTCACTCAATGAATCAATCACACAATCTAATGTAGGTTTATGACATAATAGCATTTTCAGCAGTTCAATGTTTCTAGATTCGTTGATGGCAATGGTTATACATGTATATCCGTTATTTGATCTAATGTTGACATCTGAACCGGATTCTAGCAGTAAAGATACTAGAGATTGTTTATTATATCTAACAGCCTTGTGAAGAAGTGTTTCTCCTCGTTTGTCAATCATGTTAATGTCTTTAAGATAAGGTAGACAAATGTTTATAGTACTAAGAATTGGGCAAACATAAGACATGTCACAAAGACCCTTTTTGTATGTATAAGTGTAGAAATTATAACATCCATAGTTGGATTCACATAGGTGTCCAATCGGGATCTCTCCATCATCGAGATGATTGACGGCATCTCCCCCTTCCTTTTTTAGTAGATATTTCATCGTGTAAGAATCAATATTAATATTTCTAAAGTATCTGTGTATAGCCTCTTTATTTACCACAGCTCCATATTCCAACATGCATTCCACTAGAGGGATATCGATATCGCCGAATGTCATATACTCAATTAGTATATGTTGGAGGACATCCGAGTTCATTGTTTTCAATATCAAAGAGATGGTTTCCTTATCATTTCTCCATAGTGGTACAATACTACACATTATTCCGTACGGCTTTCCATTCTCCAAAAACAATTTTACCAAATCTAAATCTACATCTTTATTGTATCTATAATCACTATTTAGATAATCAGCCATAATTCCTCGAGTGCAACATGTTAGATCGTCTATATATGAATAAGCCGTGTTATCTATTCCTTTCATTAACAATTTAACGATGTCTATATCTATATGAGATGACTTAATATAATATTGAAGAGCTGTACAATAGTTTTTATCTATAGAAGACGGCTTGATTCCGTGATTAATTAGACATTTAACAACTTCCGGACGCACATATGCTCTCGTATCCGACTCTGAATACAGATGAGCGATGATATACAGATGCAATACGGTACCACAATTTCGTGGTTGATAATCATCATACACGTATCCGTACTCGTCATCCTCATAAAGAACACTGCATCCATTTTCTATGAACAAATCAATAATTTCAGGAACAGGATCATCTGTCATTACATAATTTTCTATAACTGAACGATGGTTTTCACATTTAACACTCAAGTCAAATCCATGTTCTACCAACACCTTTATCAAGTCAACGTCTACATTTTTTGATTTCATATAGCTGAATATATTAAAGTCATTTATGTTGCTATATCCAGTAGCTTCTAGTAGAGCCATCGCTATATCCTTATTGACTTTAACATGTCTACTATTTGTGTATTCTTCTATTGGGGTAAACTGTCTCCAATTTTTATGTAATGGATTAGTGCCACTATCTAGTAGTAGTTTGACGACCTCAACATTATTACAATGCTCATTGAAAAGGTATGCGTGTAAAGCATTATTCTTGAATTGGTTCCTGGTATCATTAGGATCTCTGTCTCTCAACATCTGTTTAAGTTCATCGAGAACCACCTCCTCATTTTCCAGATAGTCAAACATTTTGACTGAATAGAAGTGAATGAGCTACTGTGAACTCTATACACCCGCACAACTAATGTCATTAAATATCATTTTTGAATGTATTTATACCATGTCAAAAACTTGTACAATTATTAATAAAAATAATTAGTGTTTAAATTTTACCAGTTCCAGATTTTACACCTCCGTTAACACCTCCATTAACCCCACTTTTTACACCACTGGACGATCCTCCTCCCCACATTCCACTGCCACTAGATGTATAAGTTTTAGATCCTTTATTACTACCATCATGTCCATGGATAAAGACACTCCACATGCCGCCACTACTACCCCCTTTAGACGACATATTAATAAGACAAGTTTAACAATAAAATTAATCACGAGTACCCTACTACCAACCACTATTATATGATTACAGTACCTTGACTAAAGTCTCTAGTCACAAGATCAATACTACCAACCTACGCTATTATATGATTATAGTTTCTATTTTTATAGGAACGCGTACGAGAAAATCAAATGTCTAAGTTCTAACGGTAGTGTTGATAAACGATTGTTATCCGCGGATACCTCATCTATCATGTTGTCTATTTTCTTACTTTGTTCTATTAACCTATTAGCATTATATATTATTTGATTATAAAACTTATATTGCTTATTAGCCCAATCTGTAAATATCGGATTATTAACATATCGTTTCTTTGTAGGTTTATTTAACTTGTACATCACTGTAAGCATGTCCGTACCATTTATTTTAATTTGACACATATCAGCAATTTCTTTTTCGCAGTCGGTTATATATTCTATATAAGATGGATACGTATCACATATGTACTTATAGTCTACTAATATGAAGTACTTAATACATATTTTCAGTAACGATTTAGCCTTATTACCTATTAATAAGTGCCTGTCGTTGGATAGGTAATCAACTGTTTTCTTAATACATTCGATGGTTGGTAATTTACTCAAAATAATTTCCAATATCTTAATATATATTTCTGCTATTTCTGGTATACATGCATGTGCCATTATAACACAAATACCAATACATGTAGACCCATATGTTGTTGTTATATTAATATCTGCGCCATTATCTATTAACCATTCTATTAGGTCAACACTATGCGACTCGATACAATAATAAAGTATACTACGTCCATGTTTATCTATTTTGTTTATATCATCGATATACGGCTTACAAATTTCTAGTATCGATAACACTTCTGACTCGTGAATAAATAAGGTAGGGAATAACGGCATAATATTTATTATGTTATCATCATTAACAACTACGTTTCCATTTTTTAAAATATACTCTACAACTTTAGGATCCCTATTGTCAAATCTTTTAAAATATTTATTTATATGCTTAAATCTATATAATATAGCTCCTTCCCTAATCATACATTTGATAACATTGATGTACACTGTATGATAAGATACATATTCTGACAATAGATCTTGTATAGAATCTGTATATCTTTTAAGAATTGAGGATATTATGACATTATTACGTAAACTATTACACAATTCTAAAATATAAAATGTATCATGGGCAGATAATAGTTTATCCACTATATAATTATCTATTTTATGATTTTTCTTCCTATATTGTTTACGTAAATAGATAGATAGAATATGCATTAGTTCATTACCGCTATAGTTACTATCGAATAACACGTCAAATATTTCCCGTTTAATATCGCATTTGTCAACATAATAATAGAGTATGGTACGTTCACGATAAGTATAATGACACATCTCGTTTTCGTGCGAAATTAAATAGTTTATCACGTCCAAAGATGTCACATAACCATCTTGTGACCTAGTAATAATATAATAATAGAGAACTGTTTTACCCATTCTATTATCATAATCAGTGGTGTAGTCATAATCTAAATAATCAAACTCGTCATCCCAATTAAAATAAATATAATCAGTACATTGAATGGGTATGATATTGTACCCATACTGTATGTTGCTACATGTAGGTATTCCTTTATCCAATAATAGTTTAAATACATCTATATTAGGATTTGATGTTGTCGCGTATTTCTCTACAATATTAATACCATTTTTGATACTATTTATTTCTATACCTTTCGAAATTAGTAATTTCAATAAGTCTATATCGATGTTATCAGAACATAGATATTCAAATATATCAAAATCATTGATATTTTTATAGTCGACTGACGACAATAACAAAATCACAACATCGTTTTTGATATTATTATTTTTTTTGGTAACGTATGCCTTTAATGGAGTTTCACCATCATACTCATATAATGGATTTGCACCACTTTCTATTAATGATTGTGCACTACTGGCATCGATGTTAAATGTTTTACAACTATCATAGAGTATCTTATCGTTAACCATGATTGGTTGTTGATGTTATCACATTTTTTGGTTTCTTTCATTTCAGTTATGTATGGATTTAGCACGTTTGGGAAGCATGAGCTCATATGATTTCAGTACTGTAGTGTCAGTACTATTAGTTTCGATCAGATCAATGTCTAGATCTATAGAATCAAAACACAATAGGTCAGAAGATAATGAATATCTGTACGCTTCTTCTTGTACTGTAACTTCTGGTTTTGTTAGATGGTTGCATCGTGCTTTAACGTCAATGGTACAAATTTTATCCTCGCTTTGTGTATATCATATTCGTCTCTAGTATAAAATTCTATATTCAAATTATCATGCGATGTGTGTACGCTAACGGTATCAATAAACGGAGCACAGCATTTAGTCAACAGTAATCCAAAATTTTTTAAAGTATATCTTAACGAAAGAAGTTGTCATCGTTAGAGTGTGGTAAATCATTGTCTACGGTACTAGATCCTCATAAGTGTATATATCTAGAGTAATATTTAATTTATCAAATGGTTGATAATATGGATGTTGTGGCAATTTCCTAATACGGAAATAAGACATAAACACGCAATAAATCTAATTGCGGACATGTTACACTCCTTAAAAAATACGAATAAACACTTTGGCTTTTAGTAAGTGTCATTTAACACTATACTCATATTAATCCATGGACTCATAATCTCTATACGGGATTAACGGATGTTCTATATACGGGGATGAGTAGTTCTCTTCTTTAACTTTATACTTTTTACTAATCATATTTAGACTGATGTATGGGTAATAGTGTTTGAAGAGCTCGTTCTCATCATCAGAATAAATCAATATCTCTGTTTTTTTGTTATACAGATGTATTACAGCCTCATATATTACGTAATAGAACGTGTAATCTACCTTATTAACTTTCACCGCATAGTTGTTTGCAAATACGGTTAATCCTTTGACCTCGTCGATTTCCGACCAATCTGGGCGTATAATGAATCTTAACTTTAATTTCTTGTAATCATTCGAAATAATTTTTAGTTTGCATCCGTAGTTATCTCCTCTATGTAACTGTAAATTTCTCAACGCGATATCTCCATTAATAATGATGTCGAATTCGTGTTGTATACCCATACTGAATTGATGAACTAATACCGACGGTATTAATAGTAATTTACTTTTCATCTTTACATACTTGGTAATAGTTTTACTATCATAAGTTTATAAATTCCACAAGCTACTATGGAATATACCAACCATCTTAGTATAGAACACATGTCTTAAAGTTATTAATTAATTACATGTTGTTTTATATATCGCTACGAATTTAAACAGAGGAATCAGTTAGGAAGAAAAAATTATCTGTCATCATCATCATCTATTGGATAACATCTCTGTATTCTACGATAGAGTGCTATTTTAAGATGTGACAGATCCGTGTCATCAAATATATACTCCATTAAAATGATTATTCCGGCAGCGAACTTGATATTGGATACATCACGACCTTTGTTAATATCCACGACAATAGACAGCAATCCCATTGTTCCATAAACAGTGAGTTTATCTTTCTTTGAAGTGATATTTTGTAGAGATCTTATAAAACTGTCGAATGACATCGTATTTATATCTTTAGCTAAATCATATATGTTACCATCATAATATCTAACAGCATCTATCTTAAACGTTTCCATCGCTGTAAAGACGTTTCCGATAGATGGTCTCGTTTCATCAGTCATACTGAGCCAACAAATGTAATCGTGTATAACATCTTTGATAGAATCAGACTCTAAAGAAAAGGAATCGGCTTTATTATACACATTCATGATAAACTTAATGAAAAATGTTTTTCGTTGTTTAAGTTGGATGAATAGTATGTCTTAATAATTGTTATTATTTCACTAATTAATATTTAGTAACGAGTACACTCTATAAAAACGAGAATGACATAACTAATCATAACTAGTTATCAAAGAATGTCTAGGACGCGTAATTTTTTATGGTATAGATCCTGTAAGCGTTGTCTGTATTCTGGAGCTATTTTCTCTATCGCATTAGTGAGTTCAGAATATGTTATAAATTTAAATCGAATAACGAACATAACTTTAGTAAAGTCGTCTATATTAACTCTTTTATTTTCTAGCCATCGTAATACCATGTTTAAGATAGTATATTCTCTAGTTACTACGATCTCATCGTTGTCTAGAATATCGCATACTGAATCTACATCCAATTTTAGAAATTGGTCTGTGCTACATATCTCTTCTATATTATTGTTGATGTATTGTCGTAGAAAACTATTACGTAGACCATTTTCTTTATAAAACGAATATATAGTACTCCAATTATCTTTACCGATATATTTGCATACATAATCCATTCTCTCAATCACTACATCTTTAAGAGTTTGGTTGTTAAGATATTTGGCTAAACTATATAATTCTATTAGATCATCAACAGAATCAGTATATATTTTTCTAGATCCAAAGATGAACTCTTTGGCATCCTCTATAATATTATCAGAAAAGATATTTTCGTGTTTTAGTTTATCAAGATTTAACCTGTTCATATCCATGATTAACGACGTCATATAACCACATAAAATAAAAATCCATTTTCATTTTTAGCACAATACTATTCATAATTGATATTGATGTAATATTTTGTTACTTTGAACGTAAAGACAGTACACGGGTCCGTATCTCCAACAAGCACGTAGTAATCAAATTTGGTGTTGTTAAACTTCGCAATATTCATCAATTTAGATAGAAACATATACTCATCATCTGTTTTAGGAATCCATGTATTATTACCACTTTCCAACTTATCATTATCCCAGGCTATGTTTCGCCCATCATCGTTGCACAGAGTGAATAATTCTTTTGTATTCGGTAGTTCAAATATATGATCCATGCATATATCGACAAAGCTATTGTAGATGTGATTTTTCCTAAATCTAATATAAAACTCGTTTACTAGCAAACATTTTCCTGATTTATCGACCAAGACACACATGGTTTCTAAATCTATCAAGTGGTGGGGATCCATAGTTATAACGCAGTAACATAAATTATTACCTTCTTGACTGTCGCTAATATCTATATACTTATTGTTATCGTATTGGATTCTACATATAGATGGCTTGTATATCAAAGATATAGAACACATAACCAATTTATATTCTCGCTTTGTATTTTCGAATCTAAAGTTAAGAGATTTAGAAAACATTATATCATCGGATGATGATATCACTGTTTCCAGAGTAGGATATATTAAAGTCTTTAAAGATTTTGTCCGATTCAAATAAATCACTAAATAATATCCCATATTATCATCTGTTATAGTCGTGTCATTAAATCTATTATATTTTATGAAAGATATATCACTGCTCACCTCTATATTTCGTACATTTTTAAACTGTTTGTATAATATCTCTCTAATACAATCAGATATATCTATTGTGTCGGTAGACGATACCGTTACATTTGAATTAATGGTGTTCCATTTTACAACTTTTAACAAGTTGACCAATTCATTTCTAATAGTATCAAACTCTCCATGATTAAATATTTTAATAGTATCCATTTTATATCACTACGGACATAAACCATTGTATATTTTTTATGTTTATTAGTGTACACATTTTGGAAGTAAGTTCCTGGATCGGATGTCACCGCAGTAATATTGTTGATTATTTCTGACATCGACGTATTATATAGTTTTTTAATTCCATATCTTTTAGAAAAGTTAAACATCCTTATACAATTTGTGGAATTAATATTATGAATCATGGTTTTTACACATAGATCTATTACAGGCGGAACATCAATTATTATGGCAGCAACTAGTATCATTTCTACATTGTTTATGGTGATGTTTATCTTCTTCCAGCGCATATAGTCTAATATCGATTCAAACGCGTGATAGTTTATACCATTCAATATAATCGCTTCATCCTTTAGATGGTGATCCTGAATGTGTTTAAAAAATTATACGGAGACGCCGTAATAATTTCCCCATTGATAGAAAATATCACGCTTTCCATTTTCTTGAAGTACTAAAAGTAATTATAATATAATGTAAAGGTTTATATATTCAATATTTTTTATAAAAAAAATCATTTTGACATTAATTCCTTTTTAAATTTCAGTCTATCATCTATAGAAACATATTCTATGAATTTATAAAATGCTTTTACGTATCCTATCGTAGGTGATAGAACCGCTAAAAAACCTATCGAATTTCTACAAAAGAATCTGTTATATGGTATAGGGAGAGTATAAAACATTAAATGTCCGTACTTATTAAAGTATTCAGTAGCCAATCCTAACTCTTTCGAATAATTATTAATGGCTCTTATTCTGTACGAATCTATTTTTTTGAACAATGGACCTAGTGGTATATCTTGTTCTATGTATCTAAAATAATGTCTGACTAGATCCGTTAGTTTAATATCCGCAGTCATCTTGTCTAGAATGGCAAATCTAACTGCGGGTTTAGGCGTAGGCGTTAGTTTAGTTTCTATATCTACATCTATGTCTTTATCTAACACCAAAAATATAATAGCTAATATTTTATTACAATCATCCGGATATTCTTCTACGATCTCACTAACTAATGTTTCTTTGGTTATACTAGTATAGTCACGATCAGACAAATAAAGAAAATCAGATGATCGATGAATAATACATTTAAATTCATCATCTGTAAGATTTTTGAGATGTCTCATTAAAATATTATTAGTGTCAGTTCTCATTATCATATATTGACAGCAGCTATTACACTTATTTTATTTTTCTGTATTTTATTACTTTTCACCATATAGATCAGTCATTAGATCATCAAAATACTTTTCAATCATCCTAAAGAGTATGGTGAACGAATCTTCCCATCTAATTTCTGAACGTCTACCAATGTCTCTAGCCACTTTGGCACTAATAGCGATCATTCGCTTAACATCTTCTACATTATTAACTGGTTGATTCAATCTATCTAGCAATGGACCGTCGGATAGCGTCATTCTCATGTTCTTAATCAATGTACATACATCGTCATCATCTACCAATTCATCAAACAATATAAGCTTTTTAAAATCATCATTATAATAGGATGGATCGCCGTCATTTCTCCAAAGAATATATCTAATAAGTAGAGTCCTCATGCTTAGTAATTTAACTATTTTAGTTAACAACTATTTTTTATGTTAAATCAATTAGTAACACCGCTATGTTTAATACTTATTCATATTTTAGTTTTAGGATCGAGAATCAATACAAAAATTAATACATCAATTTTGGAAATACTTAGTTTCCACGTAGTCAATGAAACATTTGAGCTCATCGTAAAGGACGTTCTCGTACAAGACGTAACTATAAATTGGTTTATATTTGTTCAAGATAGATACAAATCCGATAACTTTTTTGACGAATTCTACGGGATTCACTTTAAAAGTGTCATACCGGGTTCTTTTTATTCTTTTAAACAGATCGATTGTGTGATGTTGATTAGGTCTTTTACGAATTTGATACAGAATAGCGTTTACATATCCACCATAGTAATCAATAGCCATTTGTTCGTATGTCATAAATTCTTTAATTATATGACACTGTGTATTATTTAGTTCGTCCTTGTTCATCATTAGGAATCTATCCAATATGGCAATTATATTAGAACTATAACTGCGTTGTATGCGCATGTTGATGTGTCTGTTTATACAATCAATTATACTAGGATCCATACCACTACAATCGGGTAAAATTGTAGCATCATATACCATTTCTAGTACTTTAGATTCATTGTTATCCATTGCAGAGGACGTCATGATCGAATCCAAAAAAATATATTATTTTTATGTTATTTTGTTAAAAATAATCATCAAATACTTCGTAAGATACTCCTTCATGAACATAATCAGTTACAAAACGTTTATATGAAGTAAAGTATCTACAATTTTTACAAAAGTCAGGATGCATAAGTACAAAGTACGCGATAAACGGAATAATAATAGATTTATCTAGTTTATCTTTTTCTATCTCTTTCATAGTTATATACATGGTCTCAGAAGTCGGATTATGTAACATCAGCTTCGATAAAATGACTGGGTTATTTAGTCTTACACATTCGCTCATACATGTATGACCGTTAACTATAGAGTCTACACTAAAATGATTGAATAATAGATAGTCTACCATTGTTTCGTATTCAGATAGTACAGCGTAGTACATGGCATCTTCACAAATTATATCATTATCTAATAGATATTTGACGCATCTTATGGATCCCACTTCAACAGCCATCTTAAAATCGGTAGAATCATATTGCTTTCCTTTATCGTTAATAATTTCTAGAACATCATCTCTATCATAAAAGATACAAATATTAACTGTTTGATCAGTAATAACATTGCTAGTCGATATCAATTTGTTAATAAGATGCGCTGGGCTCAATGTCTTAATAAGAAGTGTAAGAGGACTATCTCCAAATTTGTTTTGTTTATTAACATCCGTTGATGGAAGTAAAAGATTTATAATGTCTACATACTTGACTGTTTTAGAGCATACAATATGGAGAGGCGTATTTCCATCATGATCTGGTTTTGAGGGACTAATTCCTAGTTTCATCATCCATGAGATTGTAGAAGCTTTTGGATTGTCTGACATAAGATGTCTATGAATATGATTTTTGCCAAATTTATCCACTATCCTGGCTTCGAATCCGATAGACATTATTTTTTTAAACACTCTTTCTGAAGGATCTGTACACGCCAACAACGGACCACATCCTTCTTCATCAACCGAGTTGTTAATCTTGGCTCCATACTGTACCAATAAATTTATTCTCTCTATGACTTCATCATCTGTTCCCGAGAGATAATATAGAGGTGTTTTATTATGTTTATCACATGCGTTTGGATCTGCGCCGTGCACCAGCAGCATCGCGACTATTCTATTATTATTAATTTTAGAAGCTATATGCAATGGATAATTTCCATCATCATCCGTCTCATTTGGAGAGTATCCTCTATGAAGAAGTTCTTCTATAAATCGTTCATCTAGTCCTTTAATGCCACAATACGCATGTAGAATGTGATAATTTCCAGAGGGTTCGATAACTTGTAGCATATTCCTAAATACATCTAAATTTTTACTATTATATTTGGCATAAAGAGATAGATAATACTCGACCGACATAATGTTGTGTTGTCCATTATAGTATAAAAATTAATATTTCTATTTCTATATATTTGCAACAATTTACTCTCTATAACAAATATCATAACTTAGTTCTTTTATGTCAAGAAGGCACTGGTTTAATTCATCTATAAATGTCACTCCATAACTACCACGCATACTATACTCAGAATTATGATAAAGATATTTATTCTTGGGGTGTAAGTAATGGGGATTAATCTTTGTTGGATCAGTCTCTAAGTTAACACATGTCACACATGATCCATTTATAGTTATATCACACGATGATGATTTATGAATTGATTCCGGAAGATCGCTATTGTATTTTGTAGTTCCACAATTCATTTCCATACATGTTATTGTCACACTAATATTATGATGAACTTTATCTAGCCGCTGAGTGGTAAACAACAGAACAGATAGTTTATTATCTTTACCAACACCCTCAGCCGCTGCCACAAATCTCTGATCCGTATCCATGATGGTCATGTTTACTTTTAGTCCGTATCCAGTCAACACTATGTTAGCATTTCTGTCGATATAGCTTTCACTCATATGACACTCACCAATAATTGTAGAATTAATGTCGTAATTTACACCAATAGTGAGTTCGGCGACAAAGTACCAGTACCGGTAATCTTGTCGATGAGGACATATAGTATTCTTGTATTCTACCGAATACCCGAGAGATGCGATACAAAAGAGTAAGACTAATTTGTAAACCATCTTACTCAAAAATATGCGACAATAGGAAATCTATCTTATACACATAATTATTCTATCAATTTTACCAATTAGTTAGTGTAATGTTAACAAAAATGTGGGATAATTTAATAGTTTTTCCTTACACAATTGACATACATGAGTCTGAGTTCCTCGTTTTTGCTAATTATTTCGTCCAATTTATTATTCTTGACATCGTCAAGATCTTTTGTATAGGAGTCAGACTTGTATTCAACATGTTTTTCTATAATCATCTTAGCTATTTCGGCATCATCCAATAGTACATTTTCCAGATTAACAGAATAGATATTAATGTCGTATTTGAACAGAGCCTGTAACATCTCAATGTCTTTATTATCTATAGCCAATTTGATGTCCGGAATGAAGAGAAGGGAATTGGTGTTTGTTGACGTCATATAGTCGAGCAAGAGAATCATCATATCCACGTGTCCATTTTTTATAGTGGTGTGAATACAACTAAGGAGAATAGCCAGATCAAAAGGAGATGGTATCTCTGAAAGAAAGTAGGAAACAATACTTACATCATTAAGCATGACAGCATGATAAAATGAAGTTTTCCATCCAGTTTTCCCATAGAACATCAGTCTCCAATTTTTCTTAACAAACAGTTTTACCGTTTGCATGTTACCACTATCAACCGCATAATACAATGCGGTGTTTCCTTTGTCATCAAATTGTGAATCATCCATTCCACTGAATAGCAAAATCTTTACTATTTTGGTATCTTCTAATGTGGCTGCCTGATGTAATGGAAATTCATTATCTAGAAGATTTTTCAATGCTCCAGCGTTCAACAACGTACATACTAGACGCACGTTATTATCAGCTATTGCATAATACAAGACACTATGACCATTGATATCCGCCTTAAATGCATCTTTGCTAGAGAGAAAGCTTTTCAGTTGCTTAGACTTCCAAGTATTAATTCGTGACAGATCCATGTCTGAAACGAGACGCTAATTAGTGTATATTTTTTCATTTTTTATAATTTTGTCATATTGTACCAGAATTAATAATATCTCTAATAGATCTGATTAGTAGATATATGGCTATCGCAAAACAACATATACACATTTAATAAAAATAATATTCATTAAGAAGATTCAGATTCCACTGTACCCATCAATATAAAATAAAATAATTATTCCTTACATCGTACCCATAAACAATATATTAAGTATATTCCACCTTACCCATAAACAATATAAATCCAGTAATATCATGTCTAATGATGAACACAAATGGTGTATTAAATTCCAGTTCTTCAGGAGATGATCTCGCCGTAGCTACCATGATAGTAGATGCCTCCGCTACAGTTCCTTGTTCGTCTACATCTATCTTTACATTCTGAAACATTTTATAAATATATAATGGGTCCCTAGTCATATGTTTAAACGACGCCTTATCTGGATTAAACATACTAGGAGCCATCATTTCGGCTATCGACTTAATATCCCTCTTGTTTTCGATAGAAAATCTAGGGAGTTTAAGATTGTACATTTTATTCCCTAATTGAGATGACCAATATTCTAATTTTGCAGGCGTGATAGAATCTGTGAAATGGGTCATATTATCACCTATTGCCAGGTACATACTAATATTAGCATCCTTATACAGAAGGCGCACCATATCATATTCTTCGTCATCGATTGTGATTGTATTTCCTTGCAATTTAGTAACTACGTTCATCATGGGAACCGTTTTCGTACCGTACTTATTAGTAAAACTAGCATTGTGTGTTTTAGTGATATCAAACGGATATTGCCACGTACCTTTAAAATATATAGTATTAATGATTGCCCATAGAGTATTATCGTCGAGCATAGTAGAATCAACTACATTAGACATACCAGATCTACGTTCTACTATAGAATTAATTTTATTAACCGCATCTCGTCTAAAGTTTAATCTATATAGGCCGAATCTATGATATTGTTGATAATACGACGGTTTAATACACACAGTACTATCGACGAAACTTTGATACGTTAGATCTGTGTACGTATATTTAGATGTTTTCATCTTAGCTAATCCGGATATTAATTCTGTAAATGCTGGACCCAGATCTCTTTTTCTCAAATTCATAGTATTCAATAATTCTACTCTAGTATTACCTGATGCAGACAATAGCGACATAAACATAGAAAACGAATACCCAAACGGTGAGAAGACAATATTATCATTATCATCCTCATCCCCATTTTGAATATTTTTATACGCTAATATACCAGCATTGATAAATCCCTGCAGACGATATGCGGATACTGAACACGCTAATGATAGTATCAATAACGCAATCATGATTTTTATGGTATTAATAATTAACCTTATTTTTATGTTTGGTATAAAAATTATTGATGTCTACACATCCTTTATAATCAACTCTAATCACTTTAACTTTTACAGTTTTCCCTACAAGTTTATCCCTATATTCAACATATCTATCCATATGCATCTCTTAACACTCTGCCAAGATAGCTTCAAAGTGAGGATAGTCAAAAAGATAAATATATAGAGTATAATCATTCTCGTATACTCTGCCCTTTATTACATCGCCCGCATTGGGCAACGAATAACAAAATGCAAGCATCGTGTTAACGGGCTCGTAAATTGGGATAAAATTATGTTTTTATTGTTTATCTATTTTATTCAAGAGAATATTCAGGAAGTTCCTTTTCTGGTTGTATCTCGTCGCAGTATATATCATTTGTACATTGTTTCATATTTTTTAATAGTCTACACCTTTTAGTAGGACTAGTATCGTACAATTCATAGCTGTATTTTGAATTCCAATCACGTATAAAAATATCTTCCAATTGTTGACGAAGACCTAATCCATCATCCGGTGTAATATTAATAGATGCTCCACATATATCCGTAAAGTAATTTCCTGTCCAATTTGATGTACCTATATACGCCGTTTTATCGGTTACCATATATTTTGCATGGTTTACCCTAGAATACGGAATGGGAGGATCAGCATCTGGTACAATAAATAGCTTTACTTCTATATCTATGTTTTTAGATTTTAGCATAGCTATAGATCTTAAAAAGTTTCTCATGATAAACGAAGATCGTTGCCAGCAACTAATCAATAGCTTAACGGATACTTGTCTGTCTATAGCGGATCTTCTTAATTCATCTTCTATATAAGGCCAAAACAAAATTTTACCCGCCTTTGAATAAATAATAGGAATAAAGTTCATAACAGATACATAAACGAATTTACTCGCATTTCCGATACATGACAATAAAGCGGTTAAATCATTGGTTCTTTCCATAGTACATAATTGTTGTGGTGCAGAAGCAATAAATACAGAGTGTGGAACACCGCTTACGTTAATACTAAGAGGATGATCTGTATTATAATACGACGGATAAAAGTTTTTCCAATTATATGGTAGATTGTTAACTCCAAGATACCAGTATACCTCAAAAATTTGAGTGAGATCCGCTGCCAAGTTCCTATTATTGAAGATCGCAATACCCAATTCCTTGACCTGAGTTAGTGATCTCCAATCCATGTTAGCGCTTCCTAAATAAATATGTGTATTATCAGATATCCAAAATTTTGTATGAAGAACTCCTCCTAGGATATTTGTAATATCTATGTATCGTACTTCAACTCCGGCCATTTGTAGTCTTTCAACATCCTTTAATGGTTTGTTGGATTTATTGACGGCTACTCTAACTCTTACTCCTCTTTTGGGTAATTGTACAATCTCGTTTAATATTACCGTGCCGAAATTCGTACCCACTTCATCCGATAAACTCCAATAAAAAGATGATATATCTAGTGTTTTTATGGTATTGGATAGAATTTCCCTCCACATGTTAAATGTAGTCAAATATACTTTATCAAATTGCATACCTATAGGAATAGTCTCTGTAATCACTGCGATTGTATTATCCGGATTCATTTTATTTGTTAAAAAAATAATCCTATATCACTTCACTCTATTAAAAATCCAAGTTTCTATTTCTTTCATGACTGATTTTTTAACTTCATCCGTTTCCTTATGAAGATGATGTTTGGCGCCTTCATAAATTTTTATTTCCCTATTACAATTTGCATGTTGCATGAAATAATATGCACCTGAAACATCGCTAATCTCATTGTTTGTTCCCTGGAGTATGAGAGTCGGGGTGTTAATCTTGGGAATTATTTTTCTAACCTTGTTGGTAGCCTTCAAGACCTGACTAGCAAATCCAGCCTTAATTTTTTCATGATTGACTAATGGATCGTATTGGTATTTATAAACTTCATCCATATCTCTAGATACTGATTCTGGACATAGCTTTCCGACTGACGCATTTGGTGTAATGGTTCCCATAAGTTTTGCAGCTAGCAGATTCAGTCTTGGAACAGCGTCTGCATTAACTAGAGGAGACATTAGAATCATTGCTGTAAACAAGTTTGGATTATCGCAAGCAGCTAGTATAGAAATTGTTGCTCCCATGGAATGACCCAATAAGAAGACTGGAACTCCTGGATAAGTAGATTTAATAGTCACCACGTGCTGTACCACATCTCTAACATACTTACCAAAGTCATCAATCATCATTTTTTCACCATTACTTCTTCCATGGCCAATATGATCATGTGAGAATACTAAAATTCCTAACGATGATATGTTTTCAGCTAGTTCGTCATAACGTCCAGAATGTTCACCAGCTCCATGACTTATGAATACTAATGCCTTAGGATATGTAATAGGTTTCCAATATTTACAATATATGTAATCATTGTCCAGATTGAACATACAGTTTGTACTCATGATTCACTATATAACTATCAATATTAACAGTTCGTTTAATGATCATATTATTTTTATGTTTTATTGATAATTGTAAAAATATACAATTAAATCAATATAGAGGAAGGAGACGGTACTGTATTTTGTGAGATAGTAATGGAGACTAAATCAGATTATGAGGATGCTGTTTTTTACTTTGTGGATGATGATGAAATATGTAGTCGCGACTCCATCATTGATCTAATAGATGAATATATCACGTGGAGAAATCATGTTATAGTGTTTAATAAAGATATTACCAGTTGTGGAAGACTGTACAAGGAATTGATAAAGTTCGATGATGTCGCTATACGGTACTATGGTATTGATAAAATTAATGAGATTGTCGAGGCTATGAGTGAAGGAGACCACTACATCAATCTTACAGAAGTCCATGATCAGGAAAGTCTATTCGCTACCATAGGAATATGTGCTAAAATCACTGAACATTGGGGATACAAAAAGATTTCAGAATCTAAATTCCAATCATTGGGAAACATTACAGATCTGATGACCGACGATAATATAAACATCTTGATACTTTTTCTAGAAAAAAAAATGAATTGATGATATAAGTGTCTTCATAACGCATTATTACGTTAGCATTCTATTATCCAGTGTTAAAAAAATTATCCTATCATGTATTTGAGAGTCTTATATGTAGCAAACATGATAACTGCAATACCCATAATCTTTAGATATTCACGCGTGCTATGGATGGCATTATCCCGCGGTGCGGAAATGTACGTTATATAATCTACAAAATAATCATCGCATATAGTATGAGATAGTAGAGTAAACATTTTTATCGTTTCTACTGGGTTCATACATCGTCTACCCAATTCGGTAATGAATGAAATTGTCGCCAATCTTACACCCAAACCCTTGTTGTTCATTAGTATAGTATTAACTTCATTATTTATGTCATAAACTGTAAATGATTCTGTAGATGCCATATCACACATGATATTCATGTCACTATTATAATCATTATTAACTTTATCACAATACGTGTTGATAATATCTACATATGATCTAGTTTTTGTGGGTAATTGTCTATACAAGTCGTCTAAACGTTGTTTACTCATATAGTATTGAACAGCCATCATTACATGGTCCCGTTCCGTTGATAGATAATCGAGTATGTTAGTAGACTTGTCAAATCTATATACCATATTTTCTGGAAGCGGATATACATAGTCGCGATCATCATTATCACTAGCCTCATCCTCTATATCATGTACATGTACATAATCTATGATATTATTATACATAAACATCGACAACATACTATTGTCTATTATCTAAGTCCTGTTGATCCAAACCCTTGATCTCCTCTATCTGTACTATCTAGAGATTGTACTTCTTCAAGTTCTGGATAATATATACGTTGATAGATTAGCTGAGCTATTCTATCTCCAGTATTTACATTAAACGTACATTTTCCATTATTAATAAGAATGACTCCTATGCTTCCCCTATAATCTTCGTCTATTACACCGCCTCCTATATCAATGCCTTTTAGGGACAGACCAGACCTAGGAGCTATTCTACCATAGCAGAACTTAGGCATGGACATACTAATATCTGTCTTAATTAACTGTCGTTCTCCAGGAGGGATAGTATAATCGTAAGCGCTATACAAATCATATCCGGCAGCACCCGGCGATTGCCTAGTAGGTGATTTAGCTCTGTTAGTTTCCTTAACAAATCTAACTGGTGAGTTAATATTCATGTTGAACATAAAAAATATCATTTTATTTCAAAATTATTTACCATTCCATTCCATCCCATATATTCCATGAATAAGTGCGATTATTGTACACTTCTATAGTATCTATATACGATCCACGATAAAATCCTCCTATCAATAGCAGTTTATTATCCACTATGATCAATTCTGGATTATCCCTCGGATAAATAGGATCATCTATCAGAGTCCATGTATTGCTGGATTCACAATAAAATTCCGCATTTCTACCAACCAAGAATAACCTTCTACCAAACACTAACGCACATGATTTATAATGAGGATAATAAGTGGATGGTCCAAACTGCCACTGATCATGATTGGGTAGCAAATATTCTGTAGTTGTATCAGTTTCAGAATGTCCTCCCATTACGTATATAACATTGTTTATGGATGCCACTGCTGGATTACATCTAGGTTTCAGAAGACTCGGCATATTAACCCAAGCAGCATCCCCGTGGAACCAACGCTCAACAGATGTGGGATTTGGTAGACCTCCTACTACGTATAATTTATTGTTAGCGGGTATCCCGCTAGCATACAGTCTGGGGCTATTCATCGGAGGAATTGGAATCCAATTGTTTGATATATAATTTACCGCTATAGCATTGTTATGTATTTCATTGTTCATCCATCCACCGATAAGATATACTACTTCTCCAACATGAGTACTTGTACACATATGGAATATATCTATAATTTGATCCATGTTCATAGGATACTCTATGAATGGATACTTGTATGATTTGCGTGGTTGTTTATCACAATGAAATATTATGTTACAGTCTAGTATCCATTTTACATTATGTATACCTCTGGGAGAAAGATAATTTGACCTGATTACATTTTTGATAAGAAGTAGCAGATTTCCTAATCTATTTCTTCGCCTCATATACCACTTAATGACAAAATCAACTACATAATCCTCATCTGGAACATTTAGTTCGTCGCTTTCTAGAATAAGTTTCATAGATAGATAATCAAAATTGTCTATGATGTCATCTTCCAGTTCCAAAAAGTGTTTGGTAATAAAGTCTTTAGTATGACATAAGAGATTGGATAGTCCGTATTCTATACCCATCATGTAACACTCGATACAATATTCCTTTCTAAAATCTCGTAGGATAAAGTTTATACAAGTGTAGATGATAAATTCTACAGATGTTAATATAGAAGCACGTAATAAATTGACGACGTTATGACTATCTATATATACCTTTCCAGTATATGAGTAAATAACTATAGAAGTTAGACTGTGAATGTCAAGGTCTAGACAAACCCTCGTAACTGGATCTTTATTTTTTGTGTATTTTTGGCGTAAATGTGTGCAAAAGTATGGAGATAACTTTTTCAATATCGTAGAATTGACTATTATATTACCTCCTATAGCTTCAATAATTGTTTTGAATTTCTTAGTCGTGTACAATGCTAATATATTCTTACAGTACACAGTATTGACAAATATCGGCATTTATGTTTCTTTAAAAGTCAACATCTAAAGAAAAATGATTGTCTTCTTGAGACATAACTCCCATTTTTTGGTATTCACCCACACGTTTTTCGAAAAAATTAGTTTTTCCTTCCAATGATATATTTTCCATGAAATCAAACGGATTGGTAACATTGTAAATTTTTTTAAATCCCAATTCAGAAATCAATCTATCTGCGACGAATTCTATATATGTTTTCATCATTTCACAATTCATTCCTATGAGTTTAACTGGAAGAGCCACAGTAAGAAATTCTTGTTCAATGGATACCGCATTTGTTATAATAAATCTAACGGTTTCTTCACTCGGTGGATGCAATAAATGTTTAAACATCAAACATGCGAAATCGCAGTGCAGACCCTCGTCTCTACTAATTAATTCGTTAGAAAACGTGAGTCCGGGCATTAGGCCACGCTTTTTAAGCCAAAATATGGAAGCGAATGATCCGGAAAAGAAGATTCCTTCTACTGCAGCAAAGGCAATAAGTCTCTCTCCATAACCGGCGCTGTCATGTATCCACTTTTGAGCCCAATCGGCCTTCTTTTTTACACAAGGCATCGTTTCTATGGCATTAAAGAGGTAGTTTTTTTCATTACTATCTTTAACATAAGTATCGATCAAAAGACTATACATTTCCGAATGAATGTTTTCAATGGCCATCTGAAATCCGTAGAAACATCTAGCCTCGGTAATCTGCACTTCTGTACAAAATCGTTCTGCTAAATTTTCATTCACTATTCCGTCACTGGCTGCAAAAAACGCCAATACATGTTTTATAAAATATTTTTCGTCTGGTGTTAGTTTATTCCAGTCATTGATATCTTTAGATATATCCACTTCTTCCACTGTCCAAAATGATGCCTCTGCCTTTTTATACATATTCCAGATGTCATGATATTGGATTGGGAAAATAACAAATCTATTTGGATTTGGTGCAAGGATAGGTTCCATAACTAAATTAACAATAGTAGTAATTTTTTTTCAGTTATCTGTATGACGACTGTACTTGGATCTTTTGTATATCGCTATCGCCGCAATCACTACAATAATTACAAGTATTATTGATAGCATTGTTATTACTACTATCATAATTAAATTATCGACATTCATGGGTGTTGAATAATCGTTATCATCATTTTGTAATTGTGACGTCATACTAGATAAATCATTTGTGAGATTGTTGTGGGAAGCGGGCACGGAAGATGCATTATCATTATTATTTAACGCCTCCCATTCGGATTCACAAATGTTACGCACGTTCAAAGTTTTATGGAAACTATAATTTTGTGAAAACAGATAACAAGAAAACTCGTCATCGTTCAAATTTTTAACGATAGTAAACCGATTAAACGTCGAGCTAATTTCTAACGCTAGCGACTCTGTTGGATATGGGTTTCCAGATATATATCTTTTCAGTTCCCCTACGTATCTATAATCATCTGTAGGAAATGGAAGATATTTCCATTTATCTACTGTTCCTAATATCATATGCGGTGGTGTAGAACCATTAAGCGCGAAAGATGTTATTTCGCATCGTATTTTAACTTCGCAATAATTTCTGGTTAGATAACGCACTCTACCAGTCAAGTCAATGATATTAGCCTTTACAGATATATTCATAGTAGTCGTAACGATGACTCCATCTTTTAGATGTGATACTCCTTTGTATGTACCAGAATCTTCGTACCTCAAACTCGATATATTTAAACAAGTTAATGATATATTAACGCGTTTTATGAATGATGATATATAACCAGAAGTTTTATCCTCTGTGGCTAGCGCTATAACCTTATCATTATAATACCAACTAGTGTAATTAATATGTGACATGACAGTGTGGGTACAAATATGTACATTATCGTCTACGTCGTATTTGATACATCCGCATTCAGCCAACAAATATAAAATTACAAAAACTCTAACGACGTTTGTACACATCTTGATGCGGTTTAATAAATGTTTTGATTTCAATTTATTGTAAAAAAAGATTCGGTTTTATACTGTTCGATATTCTCATTGCTTATATTCTCATCTATCATCTCCACACAGTCAAATCCATGGTTAACATGTACCTCATCAACCGGTAAAAGACTATCGGATTCTTCTATCATCATAACTCGAGAATATTTAATTTGGTGGTCATTATTAATCAAGTCAATTATCTTATTTTTAACAAACGTAAGTATTTTACTCATTTTTTTATAAAAACTTTTAGAAATATACAGACTCTATCGTGTGTCTATATCTTCTTTTTATATCCAATGTATTTATGTCTGATTTTTCTTCATTTATCATATATAATGGTCCAAATTCTACACGTGCTTCGGATTCATCCAGATCATTAAGGTTCTTATAATCGCAACATCCTTCTCTTCCATCTTCTACATCTTCCTTCTTATTCTTAGCGTCACAGAATCTACCACAGCAGGATCCCATGACGAGAGTCACATTAAACTAATTCATTTTCAATTATAATATACTGATTAGTAATGACAATTAAAATAAAAATATTCTTCATAACCGGTAAGAAAGTAAAAAGTTCACATTGAAACTATGTCAGTAGTTATACATCATGAGATGATATACTCTATTTTGGTGGAGGATTATATGATATAATTCGTGGATAATCATTCTTAAGACACATTTCTTCATTCGTAAATCTTTTCACATTAAATGAGTGTCCATATTTTGCAATTTCTTCATATGATGGCGGTGTACGTGGACGAGGCTGCTCCTGTTCTTGTAGTCGTCGACTGTCGTGTTTGCGTTTAGATCCCTCCATTATCGCGATCGCGTAGTGAGTACTATTTATACCTTGTAATTAAATTTTTTTATTAATTAAACGTATAAAAACGTTCCGTATCTGTATTTAAGAGCCAGATTTCGTCTAATAGAACAAATAGCTACAGTAAAAATAACTAGAATAATCGCTACACCCACTAGAAACCACGGATCGTAATACGGCAATCGGTTTTCGATAATAGGTGGAACGTATATTTTATTTAAGGACTTAACAATTGTCTGTAAACCACAATTTGCTTCCGCCGATCCTGTATTAACTATCTGTAAAAGCATATGTTGACCGGGAGGAGCCGAACATTCTCCGATATTCAATTTTTGTATATCTATAATGTTATTAACCTCCGCATACGCATTACAGTTCTTTTCTAGCTTGGATACTACACTAGGTACATCATCTAAATCTATTCCTATTTCCTCAGCGATAGCTCTTCTATCCTTTTCCGAAAGTAATGAAATCACTTCAATAAATGATTCAACCATGAGTGTGAAACTAAGTCGAGAATTACTCATGCATTTGTTAGTTATTCGGAGCGCGCAATTTTTAAACTGTCCTATAACCTCTCCTATATGAATAGCACAAGTGACATTAGTAGGGATAGAATGTTGAGCTAATTTTTGTAAATAACTATCTATAAAAAGATTATACAAAGTTTTAAACTCTTTAGTTTCTGCCATTTATCCAGTCTGAGAAAATGTCTCTCATAATAAATTTTTCCAAGAAACTAATTGGGTGAAGAATGGAAACCTTTAATCTATATTTATCACAGTCTGTTTTGGTACACATGATGAATTCTTCTAATGCTGTACTAAATTCGATATCTTTTTCGATTTCTGGATATGTTTTTAATAAAGTATGAACAAAGAAATGGAAATCGTAATACCAGTTATGTTCAACTTTGAAATTGTTTTTTATTTTCTTGTTAATGATTCCAGCCACTTGGGAAAAGTCAAAGTCGTTTAATGCCGATTTAATACGTTCATTAAAAACAAACTTTTTATTCTTTAGATGAATTATTATTGGTTCATTGGAATCAAAAAGTAAGATATTATCGGGTTTAAGATCTGCATGTAAAAAGTTGTCACAACAGGGTAGTTCGTAGATTTTAATGTATAACAGAGACATCTGTAAAAAGATAAACTTTATGTATTGTACCAAAGATTTAAATCCTAATTTGATAGCTAACTCGGTATCTACTTTATCTGCCGAATACAGTGCTAGGGGAAAAATTATAATATTTCCTCTTTCGTATTCGTAATTAGTTCTCTTTTCATGTTCGAAAAAGTGAAACATGCGGTTAAAATAGTTTATAACATTAATATTACTGTTAATAACTGCCGGATAAAAGTGGGATAGTAATTTCACGAATTTGATACTGTCCTTTCTCTCGTTAAACGCCTTTAGAAAAACTTTAGAAGAATATCTCAATGAGAGTTCCTGACCATCCATAGTTTGTATCAATAATAGCAACATATGAAGAACCCGCTTATACAGAGTATGTAAAAATGTTAATTTATAGTTTAATCCCATGGCCCACGCACACACGATTAATTTTTTTTCATCTCCCTTTAGATTGTTGTATAGAAATTTGGGTACTGTAAACTCCGCCGTAGTTTCCATGGGACTATATAATTTTGTGGCCTCGAATACAAATTTTACTACATAGTTATCTATCTTAAAGACTATACCATATCCTCCTGTAGATATGTGATAAAAATCGTCGTTTATAGGATAAAATCGTTTATCTTTTTGTTGGAAAAAGGATGAATTAATGTAATCATTCTCTTCTATCTTTAGTAGTGTTTCCTTATTAAAATTCTTAAAATAATTTAACAATCTAACTGACGGAGCCCAATTTTGGTGTAAATCTAATTGGGACATTATGTTGTTAAAATATAAACAGTCTCCTAATATAACAGTATCTGATAATCTATGGGGAGACATCCATTGATATTCAGGGGATGAATCATTGGCAACACCCATTTATTGTACAAAAAGCCCCAATTTACAAACGAAAGTCCAGGTTTGATAGAGATAAACTATTAACTATTTTGTCTCTGTTTTTAACACCTCCACAGTTTTTAATTTCTTTGGTAATGAAATTATTCACAATATCAGTATCTTCTTTATCTACCAGAGATTTTACTAACTTGATAACCTTGGCTGTCTCATTCAATAGGGTAGTGATATTTGTATGTATGATATTGATATCTTTTTGAATTGTTTCTTTTAGAAGTGATTCTTTGATGGTATCAGCATACGAATTACAATAATGCAGAAACTCAGTTAACATGCAGGAATTATAGTAAGCCAATTCCAATTGTTGCCTGTATTGTATTAGAGTATTAATATGCGCAATGATGTCCTTGCGTTTCTCTGATAGAATGCGAGCAGCGATTTTGGCGTTATCATTTGACGATATTTCTGGAATGACGAATCCTGTTTCTACTAACTTCTTGGTAGGACAAAGTGAAACAATCAAGAAAATAGCTTCTCCTCCTATTTGTGGAAGAAATTGAACTCCTCTAGATGATCTACTGACGATAGTATCTCCTTGACAGATATTGGACCGAACTACGGAAGTACCTGGAATGTAAAGCCCTGAAACCCCCTCATTTTTTAAGCAGATTGTTGCCGTAAATCCTGCACTATGCCCAAGATAGAGAGCTCCTTTGGTGAATCCATCACTATGTTTCAGTTTAACCAAGAAACAGTCAGCTGGTCTAAAATTTCCATCTCTATCTAATACAGAATCCAACTTGATGTCAGGGACTATGACCGGTTTAATGTTATATGTAACATTGAGTAAATCCTTAAGTTCATAATCATCGTTGTCATCAGTTATGTACGATCCAAACAATGTTTCTACCGGCATGGTGGATACGAAGATGCTATCCATCAGAATGTTTCCCTGATTAGTATTTTCTATATAGCTATTCTTCTTTAAACGATTTTCCGAATCAGTAACTATGTTCATTTTTTTAGGAGTAGGACGTCTAGCCAGTATGGAAGAGGATTTTCTAGATACTCTCTTCAACATCTTTGATCTCAATGGAATGCAAAACCCCATGGTGTAACAACCAACGATAAAAATAATATTGTTTTTTCACTTTTTATAATTTTACCATCTGACTCATGGATTCATTAATATCTTTACAAGAGCTACTAACGTATAATTCTTTATAACTAAACTGAGATATATACACCGGATCTATGGTTTCCATAATTGAGTAAATGAATGCTCGGCAATAACTAATGGCAAATGTATAGAACAACGAAATTATACTAGAGTTGTTAAAGTTAATATTTTCTATGAGTTGTTCCAATAAATTATTTGTTGTGACTGCGTTCAAGTCATAAATTATCTTGATACTATCCAGTAAACAGTCTTTAAGTTCTGGAATATTATCATCCCATTGTAAAGCCCCTAGTTCGACTATCGAATATCCTGCTCTGATAGCAGTTTCAATATCGACGGACGTCAATACTGTAATAAAGGTGGTAGTATTGTCATCATCGTGATAAACTACGGGAATATGGTCGTTAGTAGGTACCGTGACTTTACACAACGCGATATATAACTTTCCTTTTGTACCATTTTTAACGTAGTTGGGACGTCCTGCAGGGTATTGTTTTGAAGAAATGATATCGAGAACAGATTTGATACGATATTTGTTGGATTCCTGATTATTCACTATAATATAATCTAGACAGATAGATGATTCGATAAATAGAGAAGGTATATCGTTGGTAGGATAATACATCCCCATTCCAGTATTCTCGGATACTCTATTGATGACACTAGTTAAGAACATGTCTTCTATTCTAGAAAACGAAAACATCCTACATGGACTCATTAAAACTTCTAACGCTCCTGATTGTGTTTCGAATGCCTCGTACAAGGATTTCAAGGATGCCATAGATTCTTTGACCAACGATTTAGTATTGCGTTTAGCATCTGATTTTTTTATTAAATCAAATGGTCGGCTCTCTGGTTTACTACCCCAATGATAACAATAGTCTTGTAAAGATAAACCGCAAGAAAATTTATACACATCCATCCAAATAACCCTAGCACCGTCGGATGATATTAATGTATTATTATAGATTTTCCATCCACAGTTATTGGGCCAGTATACTGTTAGCAACGGTATATCGAATAGATTACTCATGTAACCTACTAGAATGATAGTTCGTGTACTAGTCATAATATCTTTAATCCAATCTAAGAAATCTAAAATTAGATCTTTTACACTATTAAAGTTAACAAAGGTATTACCCGGGTACGTGGATATCATATATGGTATTGGTCCATTATCAGTAATGGCTCCATAAACTGATACGGCAATGGTTTTTATATGTGTTTGATCTAATGAGGACGAAATTCGCGCCCACAATTCATCTCTAGATATGCATTTAATATCGAACGGTAACACATCAATCTCGGGACGCGTATATGTTTCTAAATTCTTAATCCAAATATAATGATGACCTATATGCCCTATTATCATACTGTCAACTATAGTATACCTAGAGAACTTTCGATACATCTGCTGTTTCCTGTAATCGTTAAATTTTACAAATCTATAACATGCTAAACCTTTTGACGACAGCCATTCATTAATTTCTGATATGGAATCTGTATTCTTAATACCGTATCGTTCTAAAGCCAGTGCTATATCTCCCTGTTCGTGGGAACGCTTTCGTATAATATCGATCAATGGATAATATGAAGTTTTTGGAGAATAATATGATTCATGATCTATTTCGTCCATAAACAATCTAGACATAGGAATTGGAGGCGATGATCTTAATTTTGTGCAATGGGTCAATCCTATAACTTCTAATATTGTAATATTCATCATCGACATAACACTATCTATGTTATCATCGTATATTAGTATACCACGACCTTCTTCATTTCGTGCCAAAATGATATACAGTCTTAAATAATTACGCAATATCTCAATAGTTTCATAATTGTTAGCTGTTTTCATCAAGGTTTGTATCCTGTTTAACATGATGGCGTTCTATAACGTCTCTATTTTCTATTTTTAATTTTTTTAAATTTTTAACGATTTACTGTGGCTAGATACCCAATCTCTTTCAAATATTTTTTTAGCCTTGCTTACAAGCTGTTTATCTATACTATTAAAACTGACGAATCCGTGATTTTGGTAATGGGTTCCGTCGAAATTTGCCGAAGTGATATGAACATATTCGTCGTCGACTATTAACAATTTTGTATTATTCTGAATAGTGAAAACCTTCACAGATAGATCATTTTGAACACACAACGCATCTAGACTTCTGGCGGTTGCCATAGAATATACGTCGTTCTTATCCCAATTACCAACTAGAAGTCTGATCTTAACTCCTCTATTAATGGCTGCTTCTATAATGGAGTTGTAAATGTCAGGCCAATAGTAGCTATTACCGTCGACACGTGTAGTGGGAACTATGGCCAAATGTTCAATATCTATACTAGTCTTAGCCGACTTGAGTTTATCAATAACTACATCAGTGTCTAGATCTCTAGAATATCCCAATAGGTGTTCTGGAGAATCAGTAAAGAACACTCCACCTATAGGATTCTTAATATGATACGCAGTGCTAACTGGCAGACAACAAGCCGCAGAGCATAAATTCAACCATGAATTTTTTGCGCTATTAAAGGCTTTAAAAGTATCAAATCTTCTACGAAGATCTGTGGCCAGCGGAGGATAATCAGAATATACGCCTAACGTTTTAATCGTATGTATAGATCCTCCAGTAAATGACGCGTTTCCTACATAACATCTTTCATCATCAGACACCCAAAAACAACCGAGTAGTAGTCCCACATTATTTTTTTTATCTATATTAACGGTTATAAAATTTATATCCGGGGAGTGACTTTGTAGCTCTCCCAGATTTCTTTTCCCTCGTTCATCTAGCAAAACTATTATTTTAATCCCTTTTTCAGATACCTCTTTTAGTTTATCAAAAATAAGCGCTCCCCTAGTAGTACTCAGAGGATTACAACAAAAAGATGCTATGTATATATATTTCTTAGCTAGAGTGATAATTTCGTTAAAACATTCAAATGTTGTCAAATGATCGGATCTAAAATCCATATTTTCTGGTAGTGTTTCTACCAGCCTACATTTTGCTCCCGCAGGTACCGATGCAAATGGCCACATTTAGTTAACATAAAAACTTATATATCCTGTTCTATCAACGATTCTAGAATATCATCGGCTATATCGCTAAAATTTTCATCAAAGTCGACATCACAACCTAACTCAGTCAATATATTAAGAAGTTCCATGATGTCATCTTCGTCTATTTCTATATCCGTATCCATTGTAGATTGTTGACCGATTATCGAGTTTAAATCATTACTAATACTCAATCCTTCAGAATACAATCTGTGTTTCATTGTAAATTTATAGGCGGTGTATTTAAGTTGGTAGATTTTCAATTATGTATCAATATAGCAACAGTAGTTCTTGCTCCTCCTTGATTTTAGCATCCTCTTCATTATTTTCTTCTACGTACATAATCATGTCTAATACGTTAGACAACACACCGACGATGGTGGCCGCCACAGACACGAATATGACTAGACCGATGACCATTTAAAAAATACTCTCTAGCTTTAACTTAAACTGTATCGATCATTCTTTTAGCACATGTATAATATAAAAACATTATTCTATTTCGAATTTAGGCTTCCAAAAATTTTTCATCCGTAAACCGATAATAATATATATAGACTTGTTAATAGTCGGAATAAATATATTAATGCTTAAACTATCATCATCTCCACGATTAGAGATACAATATTTACATTCTTTTTGCTGTTTCGAAACTTTATCAATACACGTTAATACAAACCCAGGAAGGAGATATTGAAACTGAGGCTGTTGAAAATGAAACGGCGAATACAATAATTCAGATAATGTAAAATCATGATTCCGTATTCTGATGATATTAGAACTGCTAATGGATGTCGATGGTATGTATCTAGGAGTATCTATTTTAACAAAGCATCGATTTGCTAATATACAATTATCCTTTTGATTAATTGTTATTTTATTCATATTCTTAAAAGGTTTCATATTTATCAATTCTTCTACATTAAAAATTTCCATTTTTAATTTATCTAGCCCCGCAATACTCCTCATTACGTTTCATTTTTTGTCTAGAATACCCATTTTGTTCATCTTGGTACATAGATTATCCAATTGAGAAGCGCATTTAGTAGTTTTGTACATTTTAAGTTTATTAACGAATCGTCGAAAACTAGTTATAGTTAACATTTTATTATTTGATACCCTGATATTAATACCCCTGCCGTTACTATTATTTATAACTGATGTAACCCACGTAACATTGGAATTAATTATCGATAGTAATGCATCGACACTTCCAAAATTGTCTATTATAAACTCACCGATAATTTTTTTATTGCATGTTTTCATATTCATTAGGATTATCAAATCTTTAATCTTATTACGATTGTATGCGTTGATATTACAAGACGTCATTCTAAAAGACGGAGGATTTCCATCAAATGCCAGACAATCACGTACAAAGTACATGGAAATAGGTTTTGTTCTATTACGCATCATAGATTCATATAAAACACCCGTAGAAATACTAATTTGTTTTACTCTATAAAATACTATTGCATCTATTTCATCGTTTTGTATAACGTCTTTCCAAGTGTCAAATTCCAATTTTTTTTCATTGATAGTACCAAATTCTTCTATCTCTTTAACTACTTGCATAGATAGGTAATTACAGTGATGCCTACATGCCGTTTTTTGAAACTGAATAGATGCATCTAGAAGCGATGCTACACTAGTCACGATCACCACTTTCATATTTAGAATATATGTATGTAAAAATATAGTAGAATTTCATTTTGTTTTTTTCTATGCTATAAATGAATTCTCATTTTGTATCCGCACATACTCCGTTTTATATCAATACCAAAGAAGGAAGATATCTGGTTCTAAAAGCCGTTAAAGTATGCGATGTTAGAACTGTAGAATGCGAAGGAAGTAAAGCTTCCTGCGTACTCAAAGTAGATAAACCCTCATCACCCACGTGTGAGAGAAGACCTTCGTCCCCGTCCAGATGCGAGAGAATGAATAACCCTGGAAAACAAGTCCCGTTTATGAGAACGGACATGTTACAAAATATGTTTGCTGCTAATCGCGACAACGTAACGTCAAGACTTTTGAACTAAAATACAATTATATCTTTTTCGATATTAATAAATCCGTGTCTCCCGGGTTTTTTATCTCTTTCAGTATGTGAATAGATAGGTATTTTATCTCTATTCATCATCGAATTTAAGAGATCCGATAAACATTGTTTGTATTCTCCAGATGTCAGCATCTGATACAACAATATATGTGCACATAAACCTCTGGCACTTATTTCATGTACCTTCCCCTTATCACTAAGGAGAATAGTATTTGAGAAATATGTATACATGATATTATCATGTATTAGATATACAGAATTTGTAACACTCTCGAAATCACACGATGTGTCGGCGTTAAGATCTAATATATCACTCGATAACACATTTTCATCTAGATACACTAGACATTTTTTAAAGCTAAAATAGTCTTTAGTAGTAACAGTAACTATGCGATTATTTTCATCGATGATACATTTCATCGGCATATTATTACGCGTACCATCAAAGACTATACCATGTGTATATCTAACGTATTCTAGCATAGTTGCCATACGTACATTAAACTTTTCAGGATCTTTGGATAGATCTTCCAATCTATCTATTTGAGAAAACATTTTTATCATGTTCAATAGTTGAAACGTCGGATCCACTATATAGATATTATCTATAAAGATTTTAGGAACTATGTTCATGGTATCCTGGCGAATATTAAAACTATCAATGATATGATTATCGTTTTCATCTTTTATCACCATATAGTTTCTAAGATATGGGATTTTACTTAATATAATATTATTTCCCGTAATAAATTTTATTAGAAATGCCAAATCTATAAGAAAAGTCCTAGAATTAGTCTGAAGAATATCTATATCACCGTACCGTATATTTGGATTAATTAGATATAGAGAATATGATCCGTAACATATACAACTTTTATTATGACGTCTAAGATATTCTTCCATCAACTTATTAACATTTTTGACTAGGGAAGATACATTATGACGTCCCATTACTTTTGCCTTGTCTATTACAGCGACGTTCATAGAATTTAGCATATCTCTTGCCAATTCTTCCATTGATGTTACATTATAAGAAATTTTAGATGAAATTACATTTGGAGCTTTAATAGTAAGAACTCCTAATATATCCGTGTATGTGGTCACTAATACAGATTGTAGTTCTATAATCGTAAATAATTTACCTATATTATATGTTTGAGTTTGTTTAGAAAAGTAGCTAAGTATACGATCTTTTATTTCTGATGCCGATGTATCAACATCGAAAAAAAATCTTTTTTTATTCTTTTTTACTAACGATACGAATATGTCTTTGTTAAAAACAGTTATTTTCTGAATATTTCTAGCTTGTAATTTTAACATATGATATTCGTTCACACTAGGTACTCTGCCTAAATAGGTTTCTATAATCTTTAATGTAATATTAGGAAGAGTATTCTGATCAGGATTCCTATTCATTTTGAGGATTTAAAACTCTGATTATTGTCTAATATGGTCTCAACACAAACTTTTTCACAGAGTGATAGAGTTTTTGATAACTCGTTTTTCTTAAGAAATATAAAACTACTGTCTCCAGAGCTCGCTCTATCTTTTATTTTATCTAATTCGATACAAACTCCTGATACTGGTTCAGAAAGTAATTCATTAATTTTCAGTCCTTTATAGAAGATATTTAATATAGATAATACAAAATCTTCAGTTCTTGATATCGATCTGATTGATCCTAGAACTAGATATATTAATAACGTGCTCATTAGGCAGTTTATGGCAGCTTGATAATTAGATATAGTATATTCCAGTTCATATTTATTAGATACCGCATTGCCCAGATTTTGATATTCTATGAATTCCTCTGAAAATAAATCCAAAATAACTAGACATTCTATTTTTTGTGGATTAGTGTACTCTCTTCCCTCTATCATGTTCACTACTGGTGTCCACAATGATAAATATCTAGAGGGAATATAATATAGTCCATATGATGCCAATCTAGCAATGTCGAATAACTGTAATTTTATTCTTCGCTCTTCATTATGAATTGAATCTTGAGGTATAAACCTAACACAAATTATATCATTAGACTTTTCGTATGTAATGTCTTTCATGTTATAAGTTTTTAATCCTGGAATAGAATCTATTTTAATGAGGCTTTTAAACGCAGCGTTCTCCAACGAGTCAAAGCATAATACTCTGTTGGTTTTCTTATATTCAATATTACGATTTTCTTCTTTGAATGGAATAGGTTTTTGAATTAGTTTATAATTACAACATAATAGATAAGGAAGTGTGTAAATAGTACGCGGAAAAAACATAATAGCTCCCCTGTTTTCATCCATGGTTTTAAGTAAATGATCACTGGCTTCTTTAGTCAATGGATATTCGAACATTAACCGTTTCATCATCATTGGACAGAATCCATATTTCTTAATGTAAAGAGTGATCAAATCATTGTGTTTATTGTACCATCTTGTTGTAAATGTGTATTCGGTTATCGGATCTGCTCCTTTTTCTATTAAAGTATCGATATCGATCTCGTCTAAGAATTCAACTATATCGACATATTTCATTTGTATACACATAACCATTACTAACGTAGAATGTATAGGAAGAGATGTAACGGGAACAGGGTTTGTTGATTCGCAAACTATTCTAATACATAATTCTTCTGTTAATACGTCTTGCACGTAATCTATTATAGATGCCAAGATATCTATATAATTATTTTGTAAGATGATGTTAACAATGTGATCTATATAAGTAGTGTAATAATTCATGTATTTCGATATATGTTCCAACTCTGTCTTTGTGATGTCTAGTTTCGTAATATCTATAGCGTCCTCAAAAAATATATTCGCATATATTCCCAAGTCTTCAGTTCTATCTTCTAAAAAATCTTCAACGTATGGAATATAATAATCTATTTTACCTCTTCTGATGTCATTAATGATATAGTTTTTGACACTATTTTCCGTCAATTGATTCTTATTCACTATGTCTAAAAACCGGATAGCGTCCCTAGGACGAACTACTGCCATTAATATCTCTATTATAGCTTCTGGACATAAATCATCTATTATACCAGAATTAATGGGAACTATTCCGTATCTATCTAACATAGTTTTAAGAAAGTCAGAATCTAAGACCTGATGTTCATATATTGGTTCATACATGAAATGATCTCTATTGATGATAGTGACTATTTCATTCTCTGAAAATTGGTAACTCATTCTATACACGCTTTCCTTGTTGATAAAGGATAGTATATACTCAATGGAATTTGTACCAACAAACTGTTCTCTTATGAATCGTATATCATCATCTGAAATGATCATGTAAGGCATACATTTAACAATAAGAGACTTGTCTCCTGTTATCAATATACTATTCTTGTGATAATTTATGTGTGCGGCAAATTTGTCCACGTTCTTTAATTTTGTTATAGTAGATATCAAATCCAATGGAGATACAGTTCTTGGCTTAAACAGATATAGTTTTTCTGGAACGAATTCTACAACATTATTATAAAGGACTTTGGGTATATAAGTGGGATGAAATCCTATTTTAATTAATGCGATAGCCTTGTCCTCGTGCAGATATCCAAACGCTTTTGTGATAGTATGGCATTCATTGTCTAGAAACGCTCTACGAATATCTGTAACAGATATCATCTTTAGAGAATACTAGTCGCGTTAATAGTACTAAAATTTGTATTTTTTAATCTATCTCAATAAAAAATTAATATGTATGATTCAATGTATAACTAAACTACTAACTGTTATTGATAACTAGAATCAGAATCTAATGATGACATAACTAAGAAGTTTATCTACAGCCAATTTAGCTGCATTATTTTTAGCATCTCGTTTAGATTTTCCATCTGCCTTATCGAATACTCTTCCGTCAATGTCTACACAGGCATAAAATGTAGGAGAGTTACTAGGCCCCACTGATTCAATACGAAAAGACCAATCTCTCCTAGTTATTTGACAGTACTCATTAATAACGGTGACAGGGTTAACACCTTTCCAATAAATAATTTTTTTAACCGGAATAACATCATCAAAAGACTTATGATCCTCTCTCATTGATTTTTCGCGGGATACATCATCTATTATAGCATCAGCATCAGAATCTGTAGGCCGTGTATCAGCATCCATTGTCGTAGACCAACGAGGAGGAGTATCGTTGGAGCTGTAAACCATAGCACTACGTTGAAGATCATACAGAGCTTTATTAACTTCTCGCTTCTCCATATTAAGTTGTTTAGTTAGTTGTACAGCAGTAGCTCCTTAGTCCAATGTTTTTAATAACCGCACACAATCTCTGTGTCAGAACGCTCGTCAATATAGATCTTAGAAATTTTTTTAGAGAGAACTAACGCAACTAGCAATAAAACTGATCTTATTTTATCATTTTTTTTATTCATCATCCTCTGGTGGTTCGTCGTTCCTATCGAATGTAGCTCTGATTAACCCGTCATCTATAGGTGATGCTGGTTCTGGAGATTCTGGAGGAGATGGATTATTATCTGGAAGAATCTCTGTTATTTCCTTGTTTTCATGTATCGATTGCGTTGTAACATTAAGATTGCGAAATGCTCTAAATTTGGGAGGCTTAAAGTGTTGTTTACAATCTCTACACGCGTGTCTAACTAATGGAGGTTCATCAGCGGCTCTAGTTTGAATCATCATCGGTGTAGTATTCCTACTTTTACAGTTAGGACACGGTGTATTGTATTTCTCGTCGAGAACGTTAAAATAATCGTTGTAACTCACATCCTTTATTTTATCTATATTGTATTCTACTCCTTTCTTAATGCATTTTATACCGAACAAGAGATAGCGAAGGAATTCTTTTTCGGTACCGCTAGTACCCTTAATCATATCACATAGTGTTTTATATTCTAAATGTGTGGCAATGGACGGTTTATTTCTATACGATAGTTTGTTTTTGGAATCCTTTGAGTATTCTATACCAATATTATTCTTTGATTCGAATTTAGTTTCTTCGATATTAGATTTTGTATTACCTATATTCTTGATGTAGTACTTTGATGATTTTTCCATGGCCCATTCTATTAAGTTTTCCAAGTTGGCATCATCCACATATTGTGATAGTAATTCTCGGATATCAGTAGTGACTACCGCCATTGATATTTGTTCATTTGATGAGTAACTACTAATGTATACATTTTCCATTTATAACACTTATGTATTAACTTTGTTTATTTATATTTTTTCATTATTATGTTGATATTAATAATCGTATTGTGGTTATATGGCTACAATTTCATAATGAGTTGAAGTCAGTGTCCTATGATCAATGACGATAGCTTTACTCTGAAAAGAAAGTATCAAATCGATAGTGCAGAGTCAACAATGAAAATGGATAAGACGATGACAAAGTTTCAGAATAGAGTCAAAATGGTAAAAGAAATAAATCAGACGATAAGAGCAGCACAAACTCATTACGAGACATTGAAACTAGGATATATAAAATTTAAGGGAATGATTAGGACTACTACTCTAGAAGATATAGCACCATCTATTCCAAATAATCAGAAAACTTATAAACTATTCTCGGACATTTCAGTCATTGGCAAAGCATCACAGAATCCGAGTAAGATGATATATGCTCGCTGCTTTACATGTTTCCCAATTTGTTTGGAGATGACCATAGATTCATTTGTTATAGAATGCATCCAACATTGTTCATGATATAGTTGAATCATGTATGCCTGTTCGTATGCCTGTGGCTAAGATACTGTGTAAAGAAATGGTAAATAAATACTTTGAGAATCTTTAAGAGTGCATTGACTTTGTTAGTGAATAGGCATTCCATCTTTCTCCAATACTAATTCAAATTGTTAAATTAATAATGGAATAGTATAAATAGTTATTAGTGATAGGATAGTAAACATAATTATTAGAATAGTAGTGTAGTATCATAGATAACTCTCTTCTATAAAAAATGGATTTTATTCGTAGAAAGTATCTTATATACACAGTAGAAAATAATATAGATTTTTTAAAGGATGATACATTAAGTAAAGTAAACAATTTTACCCTCAATCATGTACTAGCTCTCAAGTATCTAGTTAGCAATTTTCCTCAACATGTTATTACTAAGGATGTATTAGCTAATACCAATTTTTTTGTTTTCATACATATGGTACGATGCTGTAAAGTATACGAAGCGGTTTTACGACACGCATTTGATGCACCCACGTTGTACGTTAAAGCATTGACTAAGAATTATTTATCGTTTAGTAACACAATACAGTCGTACAAGGAAACAGTGCATAAACTAACACAAGATGAAAAATTTTTAGAGGTTGCCGAATACATGGACGAATTAGGAGAACTTATAGGCGTAAATTATGACTTAGTTCTTAATCCATTATTTCACGGAGGGGAACCCATCAAAGATATGGAAATCATTTTTTTAAAACTGTTTAAGAAAACAGACTTCAAAGTTGTTAAAAAATTAAGTGTTATAAGATTACTTATTTGGGCATACCTAAGCAAGAAAGATACAGGCATAGAGTTTGCGGATAATGATAGACAAGATATATATACTCTATTTCAACAAACTGGTAGAATAGTCCATAGCAATCTAACAGAAACGTTTAGGGATTATATCTTTCCCGGAGATAAGACTAGCTATTGGGTGTGGTTAAACGAAAGTATAGCTAATGATGCGGATATCGTTATTAATAGACCCGCCATTACCATGTATGATAAAATTCTTAGTTATATATACTCTGAGATAAAACAGGGACGCGTTAATAAAAACATGCTTAAGTTAGTTTATATCTTTGAGCCTGAAAAAGATATCAGAGAACTTCTGCTAGAAATCATATATGATATTCCTGGAGATATCCTATCTATTATTGATGCAAAAAACGACGATTGGAAAAAATATTTTATTAGTTTTTACAAAGCTAATTTTATTAACGGTAATACATTTATTAGTGATAGAACGTTTAACGATGACTTATTCAGAGTTGTTGTTCAAATAGATCCCGAATATTTCGATAATGAACGAATTATGTCTTTATTCTATACGAGTGCTGCGGACATTAAACGATTTGATGAGTTAGATATTAATAACAGTTATATATCTAATATAATTTATGAGGTGAACGATATCACATTAGATACAATGGATGATATGAAGAAGTGTCAAATCTTTAACGAGGATACGTTGTATTATGTTAAGGAATACAATACATACCTGTTTTTGCACGAGTCGGATCCCATGGTCATAGAGAACGGAATACTAAAGAAACTGTCATCTATAAAATCCAAGAGTAGACGGCTGAACTTGTTTAGCAAAAACATTTTAAAATATTATTTAGACGGACAATTGGCTCGTCTAGGTCTTGTGTTAGATGATTATAAAGGAGACTTATTAGTTAAAATGATAAACCATCTCAAATCTGTGGAGGATGTATCCGCATTCGTTAGATTTTCTACAGATAAAAACCCTAGTATTCTTCCATCGCTAATCAAAACTATTTTAGCTAGTTATAATATTTCCATCATCGTCTTATTTCAAAGGTTTTTAAGAGATAATCTATATCATGTAGAAGAATTCTTGGATAAAAGCATCCATCTAACCAAGACGGATAAGAAATATATACTTCAATTGATAAGGCACGGTAGATCATAGAACAAACCAAATATATTATTAATAATTTGTATATACATAGATATAATTATCACATATTAAAAAATAACACATTTTTGATAAATGGAAACCGTTGCAACAATTCAGACTCCCACCAAATTAATGAATAAAGAAAATGCAGAAATGATTTTGGAAAAAATTGTTAATCATATAGCTATGTATATTAGTGACGAATCAATATATTCAGAAAATAATCCTGAATATATTGATTTTCGTAACAGATACGGAGACTATAGATCTCTCATTATAAAAAGTGATCACGAGTTTGTAAAGCTATGTAAAGATCATGCAGAGAAAAGTTCTCCAGAAACGCAACAAATGATTATCAAACACATATACGAACAATATCTTATTCCAGTATCTGAAGTACTATTAAAACCTATAATGTCCATGGGTGACATATTTACATATAACGGATGTAAAGACAATGAATGGATGCTAGAACAACTCTCTACCCTAAACTTTAACAATCTCTACACATGGAACTCATGTAGCATAGGCAATGTAACGCGTCTGTTTTATACATTTTTTAGTTATCTGATGAAAGATAAACTAAATATATAAGTATAATCCCATTCTAATACTTTAACCTGATGTATTATTACCTGCATCTTATTAGAATATTAACCTAACTAAAAGACATAAAAAGCGGTAGGATATAAATATTATGGCCGCAACCGTTCCGCGTTTTGACGATGTGTACAAAAATGCACAAAGAAGAATTCTAGATCAAGAAACATTTTTTAGTAGAGGTCTAAGTAGACCGTTAATGAAAAACACATATCTATTTGATAATTACGCGTATGGATGGATACCAGAAACTGCAATTTGGAGTAGTAGATACGCAAACCTAGATGCTAGTGACTATTATCCCATTTCGTTGGGATTACTTAAAAAGTTTGAATTTCTCATGTCTCTATATAAAGGTCCTATTCCCGTATATGAAGAAAAAGTAAATACTGAATTCATTGCTAATGGATCTTTCTCCGGTAGATACGTATCATATCTTAGAAAGTTTTCTGCCCTTCCAACAAACGAGTTTATTAGTTTTTTATTATTGACCTCCATCCCTATCTATAATATCTTATTCTGGTTTAAAAACACACAGTTTGATATTACTAAACACACATTATTCAGATACGTCTATACAGATAATACCAAACACCTTGCGTTGGCTAGGTATATACATCAAACAGGAGACTATAAGCCTTTGTTTAGTCGTCTCAAAGAGAATTATATATTTACTGGTCCCGTTCCAATAGGTATCAAAGATATAGATCACCCTAATCTTAGTAGAGCAAGAAGTCCATCCGATTATGAGACATTAGCTAATATTAGTACTATATTGTACTTTACCAAGTATGATCCAGTATTAATGTTTTTATTGTTTTACGTACCTGGGTATTCAATTACTACAAAAATTACTCCAGCCGTAGAATATCTAATGGATAAACTGAATCTAACAAAGAGCGACGTACAACTGTTGTAAATTATTTTATGCTTCGTAAAATGTAGGTCTTGAACCAAACATTCTTTGAAAAAATGAGATGCATAAAACTTTATTATCCAATAGATTAACTATTTCAGACGTCAATCGTTTAAAGTAAACTTCGTAAAATATTCTTTGATTGCTGCCGAGTTTAAAACTTCTATCGATAATTGTTTCATATGTTTTAATATTTACAAGTTTTTTGGTCCATGGTACATTAGCTGGACAGATATATGCAAAATAATATCGTTCTCCAAGTTCTATAGTCTCTGGATTGTTTTTATTATATTCAGTAACCAAATACATATTAGGGTTATCTGCGGATTTATAATTTGAGTGATGCATTCGACTCAACATAAATAATTCTAGAGGAGACGATCTACTATCAAATTCGGATCGTAAATCTGTTTCTAAAGAACGGAGAATATCTATACATACCTGATTAGAATTCATCCGTCCTTCAGACAACATCTCAGACAGTCTGGTCTTGTATGTCTTAATCATATTCTTATGAAACTTGGAAACATCTCTTCTAGTTTCACTAGTACCTTTATTAATTCTCTCAGGTACAGATTTTGAATTCGACGATGCCGAGTATTTCATCGTTGTATATTTCTTCTTCGATTGCATAATCAAATTCTTATATACCGCCTCAAACTCTATTTTAAAATTATTAAACAATACTCTACTATTAATCAGTCGTTCTAACTCCTTTGCTATTTCTATGGACTTATCTACATCTTGACTGTCTATCTCTGTAAACACGGAGTCGGTATCTCCATACACGCTACGAAAACGAAATCTATAATCTATAGGCAACGATGTTTTCACAATCGGATTAATATCTCTATCGTCCATATAAAATGGATTACTTAATGTATTGGCAAACCGTAACATACCGTTGGATAACTCTGCTCCATTTAGTACCGATTCTAGATACAATATCATTCTACGTCCTATGGATGTGCAACTCTTAGCCGAAGCGTATGAGTATAGAGCACTATTTCTAAATCCCATCAGACCATATACTGAGTTGGCTACTATCTTGTACGTATATTGCATGGAATCATAGATGGCCTTTTCAGTTGAACTGGTAGCCTGTTTTAACATCTTTTTATATCTGGCTCTCTCTGCCAAAAATGTTCTTAATAGTCTAGGAATGGTTCCTTCTATTGATCTATCGAAAATTGCTATTTCAGAGATGAGGTTCGGTAGTCTAGGTTCACAATGAACCGTAATATATCTAGGAGGTGGATATTTCTGAAGCAAGAGTTGATTATTTATTTCTTCTTCCAATCTATTGGTACTAACAACGACACCGACTAATGTTTCCGGAGATAGATTTCCAAAGATACACACATTAGGATACAGACTGTTATAATCAAAGATTAATACATTATTACTAAACATTTTTTGTTTTGGAGCAAATACCTTACCGCCTTCATAAGGAAACTTTTGTTTTGTTTCTGATCTAACTAAGATAGTTTTAGTTTCCAACAATAGCTTTAACAGTGGACCCTTGATGATTGTACTCGCTCTATATTCGAATACCATGGATTGAGGAAGCACATATGTTGCCGCACCAGCGTCTGTTTTTGTTTCTACTCCATAATACTCCCACAAATACTGACACAAACAAGCATCATGAATACAGTATCTAGCCATATCTAAAGCTATGTTTAGATTATAATCCTTATACATCTGAGCTAAATCAATGTCATCCTTTCCGAAAGATAATTTATATATATCATTAGGTAAAGTAGGACATGATAGTACGACTTTAAATCCATTTTCCAAAATATCTTTACGAATTACTTTACATATAATATCCTCATCAACAGTCACGTAATTACCTGTGGTTAAAACCTTTGCAAATGTATCGGCTTTGCCTTTCGCGTCCGTAGTATCGTCACCGATGAACGTCATTTCTCTAACTCCTCTATTTAATACTTTACCCATGCAACTGAACGCGTTCTTGGATATAGAATCCAATTTGTACGAATCCAATTTTTCAGATTTTTGAATGAATGAATATAGATCGAAAAATATAGTTCCATTATTGTTATTAACGTGAAACGTAGTATTGGCCATGCCGCATACTCCCTTATGACTAGACTGATTTCTCTCATAAATACAGAGATGTACAGCTTCCTTTTTGTCTGGAGATCTAAAGATAATCTTCTCTCCTGTTAATAACTCTAGACGATTAGTAATATATCTCAGATCAAAGTTATGTCCGTTAAAGGTAACGACGTAGTCGAACGTTAGTTCCAACAATTGTTTAGCTATTCGTAACAAAACTATTTCAGAACATAGAACTAGTTCTCGTTCGTAATCCATTTCCATTAGCGACTGTATCCTCAAACATCCTCTATCGACGGCTTCTTGTATTTCCTGTTCCGTTAACATCTCTTCATTAATGAGCGTAAACAGTAATCGTTTACCACTTAAATCGATATAACAGTAACTTGTATGCGAGATTGGGTTAATAAATACAGAAGGAAACTTCTTATCGAAGTGACACTCTATATCTAGAAATAAGTACGATCTTGGGATATCGAATCTAGGTATTTCTTTAGCGAAACAGTTACGTGGATCGTCACAATGATAACATCCATTGTTAATCTTTGTCAAATATTGCTCGTCCAACGAGTAACATCCGTCTGGAGATATCCCGTTAGAAATATAAAACCAACTAATATTGAAAAATTCATCCATGGTGGCATTTTGTATGCTGCGTTTCTTTGGCTCTTCTATCAACCACATATCTGCGACGGAGCATTTTCTATCTTTAATATCTAGATTATAACTTATTGTCTCGTCAATGTCTATAGTTCTCATCTTTCCCATCGGCCTCGCATTAAATGGAGGAGGAGATAATGACTGATATATTTCGTCCGTCACTACGTAATAAAAGTAATGAGGAAATCGTATAAATACGGTCTCGCCATTTCGACATCTGGATTTCAGATATAAAAATCTGTTTTCACCGTGACTTTCAAACCAATTAATACACCTAACATCCATTTCTAGAATTTAGAAATATATTTTCATTTAAATGAATCCCAAACATTGGGGAAGAGCCGTATGGACCATTATTTTTATAGTACTTTCGCAAGCGGGTTTAGACGGCAACATAGAAGCGTGTAAACGAAAACTATATACTATAGTCAGCACTCTTCCATGTCCTGCATGTAGACGACACGCGACTATCGCTATAGAGAACAATAATGTCATGTCTAGCGATGATCTGAATTATATTTATTATTTTTTCATCAGATTATTTAACAATTTGGCATTTGATCCCAAATACGCAATCGATGTGTCAAAGGTTAAACCTTTATAAACTTAACCCATTATAAAACTTATGATTAGTCACGACTGAAATAACCGCGTGATTATTTTTTGGTATAATTCTACACGGCATGGTTTCTGTGACTATGAATTCAACACCTGTTATCTTAGTGAAATCTTTAACAAACAGCAAGGGTTCGTCAAAGACATAAAACTCATTGTTTACGATCGAAATAGACCCCCTATCACACTTAAAATAAAAAATATCCTTATCCTTTACCACCAAATAAAATTCTGATTGGTCAATGTGAATGTATTCACTTAACAGTTCCACAAATTTATTTATTAACTCCGAGGCACATACATCGTCGGTATTTTTTATGACAAACTTTACTCTTCCAGCATCCGTTTCTAAAAAAATATTAACGAGTTCCATTTATATCATCCAATATTATTGAAATGACGTTGATGGACAGATGATATAAATAAGAAGGTACAGTACCTTTGTCCACCATCTCCTCCAATTCATACTCTATTTTGTCATTAACTTTAATGTGTGAAAACAGTACGCCACATGCTTCCATGACAGTGTGTAACACTTTGGATACAAAATGTTTGACATTAGTATAATTGTCCAAGACTGTCAATCTATAATAGATAGTAGCTATAATATATTCTATGATGGTATTGAAGAAGATGACAACCTTGGCATATTGATCATTTAACACAGACATGGTATCAACAAATAGCTTAAATGAAAGAGAATCAGTAATTGGAATAAGCGTCTTCTCGATGTAGTGTCCGTATACCAACATGTCTGATATTTTGATGTATTCCATTAAATTATTTAGTTTTTTCTTTTTATTCTCGTTAAACAGAATTTCTGTCAATGGACCCCAACATCGTTGACCTATTAAGTTTTGATTGATTTTTCCGTGTAAGGCGTATCTAGTCAGATCGTATAGCCTATCCAATAATCCATCGTCTGTGCGTAGATCACATCGTACACTTTTTAATTTTCTATAGAAGAGTGACAGACATCTGGAGCAATTACAGACAGCAATTTCTTTATTCTCTACAGATGTAAGATACTTGAAGATATTCCTATGATGATGCAGAATTTTGGATAACACGGTATTGATGGTATCTGTTACCATAATTCCTTTGACTGATAGTGTCAAAGTACAAGATTTCCAATCTTTTGCAATTTTCAGTACCATTATCTTTGTTTTGATATCTATATCAGACAGCATGGTACGTCTGACAACACAGGGATTAAGACGGAAAGATGAAATGATTCTCTCAACATCTTCAATAGATACCTTGCTATTTTTTTTGGCATTATCTATATGTGAGAGAATATCCTCTAGAGAATCAGTATCCTTTTTGATGATAGTGGATCTCAATGACATGGGACGTCTAAACCTTCTTATTCTATCACCAGATTGCATGGTGATTTGTCTTCTTTCTTTTATCATGATGTAATCTCTAAATTCATCGGCAAATTGTCTATATCTAAAATCATAATATGAGATGTTTACCTCTACAAATATCTGTTCGTCCAATGTTAGAGTATCTATATCAGTTTTGTATTCCAAATTAAACATGGCAACGGATTTAATTTTATATTCCTCTATTAAGTCCTCGTCGATAATAACAGAATGTAGATAATCATTTAATCCATCGTACATGGTTGGAAGATGCTCGTTGACAAAATCTTTAATTGTCTTGATGAAGGTGGGACTATATCTAACATCTTGATTAATAAAATTTATAACATTGTCCATAGGATACTTTGTAACTAGTTTTATACACATCTCTTCATTGGTAAGTTTAGACAGAATATCGTGAACAGGTGGTATATTATATTCATCAGATATACGAAGAATAATGTCCAAATCTATATTGTTTAATATATTATATAGATGTAGTGTAGCTCCTACAGGAATATCTTTAACTAAGTCAATGATTTCATCAACAGTTAGATCTATTTTAAAGTTAATCATATAGGCATTGATTTTTAAAAGGTATGTAGCCTTGACTACATTCTCATTAATTAACCATTCCAAGTCACTGTGTGTAAGAAGATTATATTCTATCATAAGCTTGACTACATTTGGTCCCGATACCATTAAAGAATTCTTATGATATAAGGAAACAGCTTTTAGGTACTCATCTACTCTACAAGAATTTTGGAGAGCCTTAACGATATCAGTGACGTTTATTATTTCAGGAGGAAAGAACCTAACATTGAGAATATCTGAATTAATAGCTTCCAGATACAGTGATTTTGGCAATAGTCCGTGTAATCCATAATCCAGTAACACGAGCTGGTGCTTGCTAGACACCTTTTCAATGTTTAATTTTTTTGAAATAAGCTTTGATAAAGCCTTCCTCGCAAATTCCGGATACATGAACATGTCGCCAACATGATTAAGTATTGTTTTTCATTATTTTTATATTTTCTCAACAAGTTCTCAATACCCCAATAGATAATAGAATATCACCCAATGCGTCCATGTTGTCTATTTCCAACAGGTCGCTATATCCACCAATAGAAGTTTTCCCAAAAAAGATTCTAGGAACAGTTCTACCACCAGTAATTTGTTCAAAATAGTCACGCAATTCATTTTCGGGTTTAAATTCTTTAATATCTACAATTTCATACGCTCCTCTTTTGAAACTAAACTTATTTAGAATATCCAGTGCGTTTCTACAAAAAGGACATGTAAACTTGACAAAAATTGTCACTTTGTTATTGGCCAACCTTTGTTGTACAAATTCCTCGGCCATTTTTAATATTTAAGTGATACAAAACTATCTCGACTTATTTAACTCTTTAGTCGAGATATATGGACACAGATAGCTATATGATAACCAACTACAGAAGACAAACGCTATAAAAAACATAATTACGACGAGCATATTTATAAATATTTTTATTCAGTATTACTTGATATAGTAATATTAGGCACAGTCAAACATTCAACCACTCTAGATACATTAACTCTCTCATTTTCTTTAACAAATTCTGCAATATCTTCGTAAAAAGATTCTTGAAACTTTTTAGAATATCTATCGACTCTAGATGAAATAGCGTTCGTCAACATACTATGTTTTGTATACATAAAGGCGCCCATTTTAACAGTTTCTAGTGACAAAATGCTAGCGATCCTAGGATCCTTTAGAATCACATAGATTGACGATTCGTCTCTCTTAGTAACTCTAGTAAAATAATCATACAATCTAGTACGCGAAATAATATTATCCTTGACTTGAGGAGATCTAAACAATCTAGTTTTGAGAACATCGATAAGTTCATCGGGAATTACATACATACTATCTTTAATAGAACTCTTTTCATCCAGTTGAATGGATTCGTCCTTAACCAACTGATTAATGAGATCTTCTATTTTATCATTTTCTAGATGATATGTATGTCCATTAAAGTTAAATTGTGTAGCGCTTCTTTTTAGCCTAGCAGCCAATACTTTAACATCACTAATATCGATATACAAAGGAGATGATTTATCGATGGTATTAAGAATTCGTTTTTCGACATCCGTCAAAACCAATTCCTTTTTGCCTGTATCATCCAGTTTGCCATTCTTTGTAAAGAAATTATTTTCTACTAGACTATTAATAAGACTGATAAGGATTCCTCCATAATTGCACAATCCAAACTTTTTCACAAAACTAGACTTTACGAGATCTACAGGAATGCGTACTTCAGGTTTCTTAGCTTGTGATTTTTTCTTTTGTGGACATTTTCTAGTGACCAACTCATCTACCATTTCATTGATTTTAGCAGTGAAATAAGCTTTCAATGCACGGGCACTGATACTATTGAAAACGAGTTGATCTTCAAATTCCGCCATTTAAGTTCACCAAACAACTTTTAAATACAAATATATCAATAGTAGTAGAATAAGAACTATAAAAAAAATAATAATTAACCAATACCAACCCCAACAACCTGTATTATTAGTTGATGTGACAGTTTTCTCATCACTTAGAACAGATTTAACAATTTCTATAAAGTCTGTCAAATCATCTTCCTGAGAACCCATAAATACACCAAATATAGCAGCGTACAACTTATCCATTTATACATTGAATATTGGCTTTTCTTTATCGCTATCTTCATCATATTCATCATCAATATCAACAAGTCCCAGATTACGAACCAGATCTTCTTCTACATTTTCAGTCATTGATACGCGTTCACTATCTCCAGAGAGTCCGATAACGTTAGCCACTACTTCTCTATCAATGATTAGTTTCTTGAGCGCGAATGTAATTTTTGTTTCCGTTCCGGATCTATAGAAAACTACAGGTGTAATAATTGCCTTGGCTAATTGTCTTTCTCTTTTACTGAGTGATTCTAGTTCACCTTCTATAGATCTGAGAATGGATGATTCTCCAGTCGAAACATATTCTACCATGGCTCCGTTTAATTTGTTGATGAAGATGGATTCATCCTTAAATGTTTTCTCTGTAATAGTTTCCGCCGAAAGACTATGCAAAGAATTTGGAATGCGTTCCTTGTGTGTAATGTTTCCATAGACAGCTTCTAGAAGTTGATACAACATAGGACTAGCCGCGGTAACTTTTATTTTTAGAAAGTATCCATCGCTTCTATCTTGTTTAGATTTATTTTTATAAAGTTTAGTCTCTCCTTCCAACATAATAAAAGTGGAAGTCATCTGACTAGATAAACTATCAGTAAGTTTTATAGAGATAGATGAACAATTAGCGTATTGAGAAGCATTTAGTGTAACGCATTCGATACATTTTGCATTAGATTTACTAATCGATTTTGCATACTCTATAACACCCGCACAAGTCTGTAGAGAATCGCTAGATGCTGTAGGTCTTGGTGAAGTTTCAACTCTCTTCTTGATTACCTTACTCATGATTAAACCTAAATAATTGTACTTTGTAATATAATGATATATATTTTCACTTTATCTCATTTGAGAATAAAAATGTTTTTGTTAACCACTGCATGATGTACAGATTTCGGAATCGCAAACCACTTGTGGTTTTATTTTATCCTTGTCCAATGTGAATTGAATGGGAGCGGATGCGGGTTTCGTACGTAGATAGTACATTCCCGTTTTTAGACCGAGACTCCATCCGTAAAAATGCATACTCGTTAGTTTGGAATAACTCGGATCTGCTATATGGATATTCATAGATTGACTTTGATCGATGAAGGCTCCCCTGTCTGCAGCCATTTTTATGATCGTCTTTTGTGGAATTTCCCAAATAGTTTTATAAACTCGCTTAATATCTTCTGGAAGGTTTGTATTCTGAATGGATCCACCATCTACCATAATCCTATTCTTGATCTCATCATTCCATAATTTTCTCTCGGTTAAAACTCTAAGGAGATGCGGGTTAACTACTTGGAATTCTCCAGACAATACTCTCCGAGTGTAAATATTACTGGTATACGGTTCCACCGACTCATTATTTCCCAAAATTTGAGCAGTTGATGCAGTCGGCATAGGTGCCACCAATAAACTATTTCTAAGACCGTATGTTCTGATTTTATCTTTTAGAGGTTCCCAATTCCAAAGATCCGACGGTACAACATTCCAAAGATCATATTGTAGAATACCGTTACTGGCGTACGATCCTACATATGTATCATATGGTCCTTCCTTCTCAGCTAGTTTACAACTCGCCTCTAATGCACCGTAATAAATGGTTTCAAAGATCTTCTTATTTAGATCTTGTGCTTCCAGGCTATCAAATGGATAATTTAAGAGAATAAACGCGTCCGCTAATCCTTGAACACCAATACCGATAGGTCTATGTCTCTTATTAGAGATTTCAGCTTCTGGAATAGGATAATAATTAATATCTATAATTTTATTGAGATTTCTGACAATTACTTTGACCACATCCTTCAGTTTGAGAAAATCAAATCGCCCATCTATTACAAACATGTTCAATGCAACAGATGCCAGATTACACACGGCTACCTCATTAGCATCCGCATATTGTATTATCTCAGTGCAAAGATTACTACACTTGATGGTTCCTAAATTTTGTTGATTACTCTTTTTGTTACACGCATCCTTATAAAGAATGAATGGAGTACCAGTTTCAATCTGAGATTCTATAATCGCTTTCCAGACGACTCGAGCCTTTATTATACATTTGTATCTCCTTTCTCTTTCGTATAGTGTATACAATCGTTCGAACTCGTCTCCCCAAACATTGTCCAATCCAGGACATTCATCCGGACACATCAACGACCACTCTCCGTCATCCTTCACTCGTTTCATAAAGAGATCAGGAATCCAAAGAGCTATAAATAGATCTCTTGTTCTATGTTCATCGTTTCCTGTATTCTTTTTAAGATCGAGGAACGCCATAATATCAGAATGCCACGGTTCCAAGTATATGGCCATAACTCCAGGCCGTTTGTTTCCTCCCTGATCTATGTATCTAGCGGTGTTATTATAAACTCTCAACATTGGAATAATACCGTTTGATATACCATTGGTACCGGAGATATAGCTTCCACTGGCACGAATATTACTAATTGATAGACCTATTCCCCCTGCCATTTTAGAGATTAATGCGCATCGTTTTAACGTGTCATAGATGCCTTCTATGCTATCATCGATCATGTTAAGTAGAAAACAGCTAGACATTTGGTGACGAGTAGTTCCCGCATTAAATAAGGTAGGAGAAGCGTGCGTAAACCATTTTTCAGAAAGTAGATTGTACGTCTCAATAGCTGAGTCTATATCCCATTGATGAATTCCTACTGCGACACGCATTAACATGTGCTGAGGTCTTTCAACAATTTTGTTGTTTATTTTCAACAAGTAGGATTTTTCCAAAGTTTTAAAACCAAAATAGTTGTATGAAAAGTCTCGTTCGTAAATAATAACCGAATTGAGCTTATCCTTATATTTGTTAACTATATCCATGGTAATACTTGAAATAATCGGAGAATGTTTCCCATTTTTAGGATTAACATAGTTGAATAAATCCTCCATCACTTCACTAAATAGTTTTTTTGTTTCCTTGTGTAGATTTGATATGGCTATTCTGGCGGCTAGAATGGCATAATCCGGATGTTGTGTAGTACAAGTGGCTGCTATTTCGGCTGCCAGAGTGTCCAATTCTACCGTTGTTACTCCATTATATATTCCTTGAATAACCTTCATAGCTATTTTAATAGGATCTATATGATCAGTGTTTAAGCCATAGCACAATTTTCTAATACGAGACGTGATTTTATCAAACATGACATTTTCCTTGTATCCATTTCGTTTAATGACAAACATTTTTGTTGGTGTAATAAAAAAAATTATTTAATTTTTCATTAATAGGGATTTGACGTATGTAGCGTACAAAATTATCGTTCCTGGTATATAGATAAAGAGTCCTATATATTTGAAAATCGTTACGGTTCGATTAAACTTTAATGATTGCATTGTGAATATATCATTAGGATTTAACTCCTTGACTATCATGGCGGTGCCAGAAATTACCATCAAAAGCATTAATACAGTTATGCAGATCGCAGTTAGAACGGTTATAGCATCCACCATTTATATCTAAAAATTAGATCAAAGAATATGTGACAACGTCCTAGTTGTATACTGAGAATTGACGAAACAATGTTTCTTACATATTTTTTTCTTATTAGTAACCGACTTAATAGTAGGAACTGGAAAACTAGACTTGATTATTCTATAAGTATAGATACCCTTCCAAATAATGTTCTCTTTGATAAAAGTTCCAGAAAATGTAGAATTTTTTAAAAAGTTATCTTTTGCTATTACTAATATCGTGGTTAGACGCTTATTATTAATATGAGTGATGAAATCCACACCGCTTCTAGATATCGCTTTTATTTCCACATTAGATGGTAAATCCAATAGTGAAACTATCTTTTTAGGAATGTATGGACTCGCGTTTAGAGGAGTGAACGTCTTCGGAGTAGTAAAGGATGATTCGTCAAATGAATAAACAATTTCACAAATGGATGTTAATGTATTAGTAGGAAATTTTTTGACGCTAGTGGAATTGAAGATTCTAATGGATGATGTTCTACCTATTTCATCCGATAACATGTTAATTTCCAATACCAACGGTTTTAATATTTCGATGATATACGGTAGTCTCTCTTTCGGACTTATATAGCTTATTCCACAATACGAGTCATTATATACTCCAAAAAACAAAATAACTAGTATAAAATCTGTATCGAATGGGAAAAACGAAATTATCGATATAGGTATAGAATCCGGAACATTGAACGTATTAATACTTAATTCTTTTTCAGTGGTAAGAACCGATAGGTTATTGACATTGTATGGTTTTAAATATTCTATAACTTGAGACTTGATAGATATTAATGACGAATTGAAAATTATTTTTATCACCACGTGTGTTTCAGGATCATCGTCGACGCCAGTTAACCAACCGAATGGAGTAAAATAAATATCATTAATATATGCTCTAGATATTAGTATTTTTATTAATCCTTTGATTATCATCTTCTCGTACGCGAATGATTCCATGATCAAGAGTGATTTGAGAACATCCTCCGGAGTATTAATGGGTTTAGTAAACAGTCCATCGTTGCAATAATAAAAGTTGTCCAAGTTAAAGGATATTATGCATTCGTTTAAAGATATCACCTCATCTAACGGAGACAATTTTTTGGTAGGTTTTAGAGACTTTGAAGCTACTTGTTTAACAAAGTTATTCATCGTCGTCTACTATTCTATTTAATTTTGTAGTTAATTTATCACATATCACATTAATTGACTTTTTGGTCCACTTTTCCATACGTTTATATTCTTTTAATCCTGCGTTATCCGTTTCCGTTATATACAGGGATAGATCTTGCAAGTTAAATAGAATGCTCTTAAATAATGTCATTTTTTTATCCGCTAAAAATTTAAAGAATGTATAAACTTTTTTCAAAGATTTAAAACTTTTAGGTGGAGTTCTGGTACACAATATCATAAACAAACTAATAAACATCCCACATTCAGATTCCAACAATTGATTAACTTCCACATTAATACAGCCTATTTTCGCTCCAAATGTACATTCGAAAAATCTGAATAAAACATCAATATCGCAATTTGTATTATCCAATACAGAATGTCTGTGATTCGTGTTAAAACCATCGGAAAAAGAATAGAAATAAAAATTATTATAATGGTGGAATTCAGTTGGAATATTGCCTCCGGAGTCATAAAAGGATACTAAACATTGTTTTTTATCGTAAATTACACATTTCCAATGAGACAAATAACAAAATCCAAACATTACAAATCTAGAGGTAGAACTTTTAATTTTGTCTTTAAGTATATACGATAAGATATGTTTATTCATAAACGCGTCAAATTTTTCATGAATAGCTAAGGAGTTTAAGAATCTCATGTCAAATTGTCCTATATAATCCACTTCGGATCCATAAGCAAACTGAGAGACTAAGTTCTTAATACTTCGATTGCTCATCCAGGCTCCTCTCTCAGGCTCTATTTTCATCTTGACGACCTTTGGATTTTCACCAGTATGTATTCCTTTACGTGATAAATCATCAATTTTCAAATCCATTTGTGAGAAGTCTATCGCCTTAGATACTTTTTCCCGTAGTTGAGGTTTAAAGAAATACGCTAACGGTATACTAGTAGGTAACTCAAAGACATCATATATAGAATGGTAACGCGTCGTTAACTCGTCGGTTAACTCTTTCTTTTGATCGAGTTCATCGCTACTATTGGGTCTGCTCAGGTGCCCCGACTCTACTAGTTCCAACATCATACCGATAGGAATACAAGACACTTTGCCAGCGGTTGTAGATTTATCATATTTCTCCACCACATATCCGTTACAATTTGTTAAGAATTTAGATACATCTATATTGCTACATAATCCAGCTAGTGAATATATATGACATAATAAATTGGTAAATCCTAGTTCTGGTATTTTACTAATTACTAAATCTGTATATCTTTCCATTTATCATGGAAAAGAATTTACCAGATATCTTCTTTTTTCCAAACTGCGTTAATGTATTCTCTTACAAATATTCACAAGATGAATTCAGTAATATGAGTAAAACGGAACGTGATAATTTCTCATTGGCTGTGTTTCCAGTGATAAAACATAGATGGCATAACGCACACGTTGTAAAACATAAAGGAATATACAAAGTTAGTACAGAAGCACGTGGAAAAAAAGTATCTCCTCCATCACTAGGAAAACCCGCACATATAAACCTAATGTCGAAGCAATATATATATAGTGAGTATGCAATAAGCTTTGAATGTTATAGTTTTCTAAAATGTATAACAAATACAGAAATCAATTCGTTCGATGAGTATATATTAAGAGGACTATTAGAAGCTGGTAATAGTTTACAGATATTTTCCAATTCCGTAGGTAAACGAATAGATACTATAGGTGTACTAGGGAATAAGTATCCATTTAGCAAAATTCCATTGGCCTCATTAACTCCTAAAGCACAACGAGAGATATTTTTAGCGTGGATTTCTCATAGACCTGTAGTTTTAACTGGAGGAACCGGAGTGGGTAAGACGTCACAGGTACCCAAGTTATTGCTTTGGTTTAATTATTTATTTGGTGGATTCTCTTCTCTAGATAAAATCACTGACTTTCACGAAAGACCAGTCATTCTATCTCTTCCTAGGATAGCTTTAGTTAGATTGCATAGCAATACCATTTTAAAATCATTGGGATTTAAGGTACTAGATGGATCTCCTATCTCTTTACGGTACGGATCTATACCGGAAGAATTAATAAACAAACAACCAAAAAAATATGGAATTGTATTTTCTACCCATAAGTTATCTCTAACAAAACTATTTAGTTATGGCACTATTATTATAGACGAAGTTCATGAGCATGATCAAATAGGAGATATTATTATAGCAGTAGCGAGAAAACATCATACGAAAATAGATTCTATGTTTTTAATGACTGCCACGTTAGAGGATGACAGGGAACGTCTAAAAATATTTTTACCTAATCCCGCATTTATACATATTCCTGGAGATACACTGTTTAAAATTAGCGAGGTATTTATTCATAATAAGATAAATCCATCTTCCAGAATGGCATATATAGAAGAAGAAAAGAGAAATTTAGTTACTGCTATACAGATGTATACTCCTCCTGATGGATCATCCGGTATAGTCTTTGTGGCATCCGTTGCACAGTGTCACGAATATAAATCATATTTAGAAAAAAGATTACCGTATGATATGTATATTATTCATGGTAAGGTCTTAGATATAGACGAAATATTAGAAAAAGTGTATTCATCACCTAATGTATCGATAATTATTTCTACTCCTTATTTGGAATCCAGCGTTACTATACGCAATGTTACACACATTTATGATATGGGTAGAGTTTTTGTCCCCGCTCCTTTTGGAGGATCACAACAATTTATTTCTAAATCTATGAGAGATCAACGAAAAGGAAGAGTAGGAAGAGTTAATCCTGGAACATACGTATATTTCTATGATCTGTCTTATATGAAATCTATACAGCGAATAGATTCAGAATTTCTACATAATTATATATTGTACGCTAATAAGTTTAATCTAACACTCCCCGAAGATTTGTTTATAATCCCTACAAATTTGGATATTCTATGGCGTACAAAGGAATATATAGACTCGTTCGATATTAGTACAGAAACATGGAATAAATTATTATCCAATTATTATATGAAGATGATAGAGTATGCTAAACTTTATGTACTAAGTCCTATTCTCGCTGAGGAGTTGGATAACTTTGAGAGGACGGGAGAATTAACTAGTATTGTACAAGAAGCCATTTTATCTCTAAATTTACAAATTAAGATTTTAAAATTTAAACATAAAGATGATGATACGTATATACACTTTTGTAGAATATTATTCGGTGTCTATAACGGAACAAACGCTACTATATATTATCATAGACCTCTAACGGGATATATGAATATGATTTCAGATACTATATTTGTTCCTGTAGATAATAACTAAAAATCAAAATCTAATGACCACATCTTTTTTTAGAGATGAAAAATTTTCCACATCTCCTTTTGTAGACACGACTAAACATTTTGCAGAAAAAAGTTTATTATTATTTAGATAATCGTATACTTCATCAGTGTAGATAGTAAATGTGAACAGATAAAAGGTATTCTTGCTCAATAGATTGGTAAATTCCATAGAATATATTAATCCTTTCTTCTTGAGATCCCACATCATTTCAACCAAAGACGTTTTATCCAATGATTTACCTCGTACTATACCACATACAAAACTAGATTTTGCAGTGATGTCGTACCTGGTATTCCTACCAAACAAAATTTTACTTTTAGTTCTTTTAGAAAATTCTAAGGTAGAATCTCTATTTGTCAATATGTCATCTATGGAATTACCACTAGCAAAAAATGATAGAAATATATATTGATACATCGCAGCTGGTTTTGATCTACTATACTTTAAAAACGAATCAGATTCCATAATTGCTTGTATATCATCAGCTGAAAAACTATGTTTTACACGTATTCCTTCGGCATTTCTTTTTAATGATATATCTTGTTTAGACAATGATAAAGTTATCATGTCCATGAGAGACGCGTCTCCGTATCGTATAAATATTTCATTAGATGTTAGACGCTTCATTAGGGGTATACTTCTATAAGGTTTCTTAATTAGTCCATCATTGGTTGCGTCAAGAACTACTATCTGATGTTGTTGGGTATCTCTAGTGTTACACATGGCCTTACTAAAGTTTGGGTAAATAACTATGATATCTCTATTAATTATAGATGTATATATTTCATTCGTCAAGGATATTAATATCGACTTACTATCGTCATTAATACGTGTAATGTAATCATATAAATCATGCGATAGCCAAGGAAAATTCAAATAGATGTTCATCATATAATCGTCGCTATAATTCATATTAATACTTTGACATTGACTAATTTGTAATATAGCCTCGCCACGAAGAAAGCTCTCGTATTCAGTTTCATCGATAAAGGATACCGTTAAATATAACTGGTTGCCGATAGTCTCATAGTCTATTAAGTGGTAAGTTTCGTATAAATACAGAATCCCTAAAATATTATCTAATGTGGGATTAATCCTTACCATAACTGTATAAAATGGAGCCGGAGTCATAACTATTTTACCGTTTGTACTTACTGGAATAGATGAAGGAATAATCTCCGGACATGATGGTAAAGACCCAAATGTCTGTTTGAAGAAATCCAATGTTCCAGGTCCTAATCTCTTGACAAAAATTACGATATTCGATCCCGATATCCTTTGCATTCTATTTACCAGCATATCACGAACTATATTAAGATTATCTATCATGTCTATTCTCCCACCGTTATATAAATCGCCTCCGCTAAGAAACGTTAGTATATCCATACAATGGAATACTTCATTTCTAAAATAGTATTCGTTTTCTAATTCTTTAATGTGAAATCGTATACTAGAAAGGGAAAAATTATCTTTGAGTTTTCCATTAGAAAAGAACCACGAAACTAATGTTCTGATTGCGTCTGACTCCGTCGCTGAATTAATAGATTTACACCAAAAACTCATATAACTTCTAGATGTAGAAGCATTCGCTAAAAAATTAGTAGAATCAAAGGATATAAGTAGATGTTCCAACAAGTGAGCAATTCCCAAGATTTCATCTATATCATTCTCGAATCCGAAATTAGAAATTCCCAAGTAGATATCCTTTTTCATCCGATCATTGATGAAAATACGAACTTTATTCGGTAAGACGATCATTTACTAAGGAGTAAAATAGGAAGTAACGTTCGTATATCGTTATCGTCGTATAAATTAAAGGTGTGTTTTTTGCCATTAAGAGACATTATAATTTTACCAATATTGGAATTATAATATAGGTGTATTTGAGCACTAGAAACGGTCGATGCATCGGTAAATATAGCTGTATCTAATGTTCTAGTCGGTATTTCTTCATTTCGCTGTCTAATGATAGCGTTTTCTCTATCTGTTTCCATTACAGCTGCCTGAAGTTTATTGGTCGGATAATATGTAAAATAATAAGAAATACATACGAATAACAAAAATAAAATAAGATATAATAAAGATGCCATTTAGAGATCTAATTTTGTTCAACTTGTCCAAATTCCTACTTACAGAAGATGAGGAATCGTTGGAGATAGTATCTTCCTTATGTAGAGGATTTGAAATATCTTACGATGACTTAATATCGTACTTTCCAGATAGGAAATACCATAAATATATTTCTAAGGTATTTGAACATGTAGATTTATCGGAGGAATTAAGTATGGAATTCCATGATACAACTCTGAGAGATTTAGTATATCTTAGATTGTACAAGTATTCCAAGTATATACGGCCGTGTTATAAATTAGGAGATAATCTAAAAGGTATAGTTGTTATAAAGGACAGAAATATATATATTAGAGAAGCAAATGATGACTTGATAGAATATCTCCTCAAGGAATACACTCCTCAGATTTATACATATTCTAATGAGCGAGTTCCCATAGCTGGTTCAAAATTAATTCTTTGTGGATTTTCTCAAGTTACATTTATGGCGTATACAACGTCGCATATAACAACAAATAAAAAGGTAGATGTTCTCGTTTCCAAAAAATGTATAGATGAACTAGTCGATCCAATAAATTATCAAATACTTCAAAATTTATTTGATAAAGGAAGCGGAACAATAAACAAAATACTCAGGAAGATATTTTATTCGGTAACAGGTGGCCAAACTCCATAGGTAGCTTTTTCTATTTCGGATTTTAGAATTTCCAAATTCACCAGCGATTTATCGGTTTTGGTGAAATCCAAGGATTTATTAATGTCCACAAATGCCATTTGTTTTGTCTGTGGATTGTATTTGAAAATGGAAACGATGTAGTTAGATAGATGCGCGGCGAAGTTTCCTATTAGGGTTCCGCGCTTCACGTCACCCAACATACTTGAATCACCATCCTTTAAAAAAAATGATAAGATATCAACATGGAGTATATCATACTCGGATTTTAATTCTTCTACTGCCTCACTGACATTTTCACAAATACTACAATACGGTTTACCGAAAATAATCAGTACGTTCTTCATTTATGGGTATCAAAAACTTAAAATCGTTACTGCTGGAAAATAAATCACTGACGATATTAGATGATAATTTATACAAAGTATACAATGGAATATTTGTGGATACAATGAGTATTTATATAGCCGTCGCCAATTGTGTCAGAAACTTAGAAGAGTTAACTACGGTATTCATAAAATACGTAAACGGATGGGTAAAAAAGGGAGGACATGTAACCCTTTTTATCGATAGAGGAAGTATAAAAATTAAACAAGACGTTAGAGACAAGAGACGTAAATATTCTAAATTAACCAAGGACAGAAAAATGTTAGAATTAGAAAAGTGTACATCCGAAATACAAAATGTTACCGGATTTATGGAAGAAGAAATAAAGGCAGAAATGCAATTAAAAATCGATAAACTCACATTTCAAATATATTTATCTGATTATGATAACATAAAAATATCATTGAATGAGATACTAACACATTTCAACAATAATGAGAATGTTACATTATTTTATTGTGATGAACGAGACGCAGAATTCGTTATGTGTCTAGAGGCTAAAACACAGTTCTCTACCACAGGAGAATGGCCGTTAATAATAAGTACCGATCAGGATACTATGCTATTCGCGTCTGCTGATAATCATCCTAAGATGATAAAAAACTTAACTCAACTGTTTAAATTTGTTCCCTCGGCAGAGGATAACTATTTAGCAAAATTAACTGCATTAGTGAATGGATGTGATTTCTTTCCTGGACTCTATGGGGCATCTATAACACCCAACAACTTAAACAAAATACAATTGTTTAGTGATTTTACAATCGATAATATAGTCACTAGTTTGGCAATTAAAAATTATTATAGAAAGACTAACTCTACCGTAGACGTGCGTAATATTGTTACGTTTATAAACGATTACGCTAATTTAGACGATGTTTACTCGTATATTCCTCCTTGTCAATGCACTGTTCAAGAATTTATATTCTCCGCATTAGATGAAAAATGGAATGAATTTAAATCATCTTATTTAGAGAGCGTGCCGTTACCCTGCCAATTAATGTACGCATTAGAACCACGTAAGGAGATTGATGTTTCAGAAGTTAAAACTTTATCATCTTATATAGATTTCGAAAATACTAAATCAGATATCGATGTTATAAAATCTATATCCTCGATTTTTGGATATTCTAACGAAAACTGTAACACCATAGTGTTCGGCATCTATAAGGATAATTTACTACTGAGTATAAATAATTCATTTTACTTTAACGATAGTCTGTTAATAACCAATACTAAAAGTGATAATATAATAAATATAGGTTACTAGATTAAAAAATGGTGTTCCAGCTCGTGTGTTCTACATGCGGCAAAGATATTTCTCACGAACGATATAAATTGATTATACGAAAAAAATCATTAAAGGATGTACTAGTCAGTGTAAAGAACGAATGTTGTAGGTTAAAATTATCTACACAAATAGAACCTCAACGTAACTTAACAGTGCAACCTCTATTGGATATAAACTAATGGATCCGGTTAATTTTATCAAGACATATGCGCCTAGAGGTTCTATTATTTTTATTAATTATGCCATGTCATTAACTAGTCATTTGAATCCATCGATAGAAAAACATGTGGGTATTTATTATGGTACGTTATTATCGGAACACTTGGTAGTTGAATCTACCTATAGAAAAGGAGTTAGAATAGTCCCATTGGATAGATTTTTTGAAGGATATCTTAGTGCAAAAGTATACATGTTAGAGAATATTCAAGTTATGAAAATAGCAGCTGATATGTCGTTAACTTTACTAGGTATTCCATATGGATTTGGTCATGATAGAATGTATTGTTTTAAATTGGTAGCTGAATGTTATAAAAATGCCGGTATTGATACATCGTCTAAACGAATATTAGGTAAAGATATTTTTCTGAGCCAAAACTTTACAGATGATAATAGATGGATAAAGATATATGATTCTAATAATTTAACATTTTGGCAAATTGATTACCTTAAAGGGTGAGTTAATATGCATAACTACTCCTCCGTTGTTTTTTCCCTCGTTCTTTTTCTTAACGTTGTTTGCCATCACTCTCATAATGTAAAGATATTCTAAAATGGTAAACTTTTGCATATCGGATGCAGAAATTGGTATAAATGTTGTAATTGTATTATTTCCCGTCAATGGACTAGTCACAGCTCCATCAGTTTTATATCCTTTAGAGTATTTCTCACTCGTGTCTAGCATTCTAGAGCATTCCATGATCTGTTTATCGTTGATATTGGCCGGAAAGATAGATTTTTTATTTTTTATTATATTACTATTGGCAATTGTAGATATAACTTCTGGTAAATATTTTTCTACCTTTTCAATCTCTTCTATTTTCAAGCCGGCTATATATTCTGCTATATTGTTACTAGTATCAATACCTTTTCTGGCTAAGAAGTCATATGTGGTATTCACTATATCAGTTTTAACTGGTAGTTCCATTAGCCTTTCCACTTCTGCAGAATAATTAGAAATTGGTTCTTTACCAGAAAATCCAGCTACTATAATAGGCTCACCGATGATCATTGGCAAAATCCTATATTGTACCAGATTAATGAGAGCATATTTCATTTCCAATAATTCTGCTAGTTCTTGAGACATTGATTTATTTGATGAATCTATTTGGTTCTCTAGATACTCTACCATTTCTGCCGCATACAATAACTTGTTAGATAAAATCAGGGTTATCAAAGTGTTTAGTGTGGCTAGAATAGTGGGCTTGCACGTATTAAAGAATGCTGTAGTATGAGTAAACCGTTTTAACGAATTATATAGTCTCCAGAAATCTGTGGCGTTGCATACATGAACTGAATGACATCGAAGATTGTCCAATATTTTTAATAGCTGCTCTTTGTCCATTATTTCTATATTTGACTCGCAACAATTGTAGATACCATTAATCACTGATTCCTTTTTCGATGCCGGACAATAGCACAATTGTTTAGCTTTGGACTCTATGTATTCAGAATTAATAGATATATCTCTCAATACAGATTGCACTATACATTTTGAAACTATGTCAAAAATTGTAGAACGACGCTGTTCTGTAGCCATTTAACTTTAAATAATTTACAAAAATTTAAAATGAGCATCCGTATAAAAATCGATAAATTGCGCCAAATTGTGGCATATTTTTCAGAGTTCAGCGAAGAAGTGTCTATAAATGTAGACTTGACGGATGAATTAATGTATATTTTTGCCGCCTTGGGCGGATCTGTAAACATTTGGGCCATTATACCTCTCAGTGCATCAGTGTTCTACCGCGGAGCCGAAAATATTGTGTTTAACCTTCCAGTGTCCAAGGTAAAATCGTGTTTGTGTAGTTTTCACAATGATGCTATCATAAATATAGAACCTGATCTGGAAAATAATCTAGTAAAACTTTCTAGTTATCATGTAGTAAGTGTCGATTGTAACAAGGAACTGATGCCTATTAGGACAGATACTACTATTTGTCTAAGTATAGATCAAAAGAAATCTTACGTATTTAATTTTCACAAGTATGAAGAAAAATGTTGTGGTAGAACCGTCATTCATCTAGAATGGTTGTTGGGCTTTATCAAGTGTATTAGTCAGCATCAGCATTTGGCTATTATGTTTAAAGATGACAATATTATTATGAAGACTCCTGGTAATACTGATGCGTTTTCCAGGGAATATTCTATGACTGAATGTTCTCAAGAACTACAAAAGTTTTCTTTCAAAATAGCTATCTCGTCTCTCAACAAACTACGAGGATTCAAAAAGAGAGTCAATGTTTTTGAAACTAGAATCGTAATGGATAATGACGATAACATTCTAGGAATGTTGTTTTCGGATAGAGTTCAATCCTTTAAGATTAACATCTTTATGGCGTTTTTAGACTAATACTTTCAATGAGATAAATATGGGTGGCGGAGTAAGTGTTGAGCTCCCTAAACGGGATCCACCTCCGGGAGTACCCACTGATGAGATGTTATTAAACGTGGATAAAATGCATGACGTGATAGCTCCCGCTAAGCTTTTAGAATATGTGCATATAGGACCACTAACAAAAGATAAAGAGGATAAAGTAAAGAAAAGATATCCAGAGTTTAGATTAGTCAACACAGGACCCGGTGGTCTTTCGGCATTATTAAGACAATCATATAATGGAACCGCACCCAATTGCTGTCGCACTTTTAATCGTACTCATTATTGGAAGAAGGATGGAAAGATATCAGATAAGTATGAAGAGGGTGCAGTATTAGAATCGTGTTGGCCCGACGTCCACGACACTGGAAAATGCGATGTTGATTTATTCGACTGGTGTCAGGGGGATACGTTCGATATAAACATATGCCATCAGTGGATCGGTTCAGCCTTTAATAGGAGTGATAGAACTGTAGAGGGTCGACAATCGTTAATAAATCTGTATAATAAGATGCAAAGATTATGTAGTAAAGATGCTAGTGTACCAATATGTGAATTATTTTTGCATCATTTACGCGCACACAATACAGAAGATAGTAAAGAGATGATCGATTATATTCTAAGACAACAGTCGGCGGACTTTAAACAGAAATATATGAGATGTAGTTATCCCACTAGAGATAAGTTAGAAGAGTCATTAAAATATGCGGAACCTCGAGAATGTTGGGATCCAGAGTGTTCGAATGCCAATGTTAATTTCTTACTAACACGTAATTATAATAATTTAGGACTTTGCAATATTGTACGATGTAATACGAGCGTGAATAACTTACAGATGGATAAAACTTCCTCATTAAGATTATCATGTGGATTAAGCAATAGTGATAGATTTTCTACTGTTCCCGTCAATAGAGCAAAAGTAGTTCAACATAATATTAAACATTCGTTCGACCTAAAATTGCATTTGATCAGTTTATTATCTCTCTTGGTAATATGGATACTAATTGTAGCTATTTAAATGGGTGCCGCAGCAAGCATACAGACGACTGTGAATACACTCAGTGAACGTATCTCGTCTAAATTAGAACAAGAAGCGAACGCTAGTGCTCAAACAAAATGTGATATAGAAATCGGAAATTTTTATATCCGACAAAACCATGGATGTAACATCACTGTTAAAAATATGTGCTCTGCGGACGCGGATGCTCAGTTGGATGCTGTGTTATCAGCCGCTACAGAAACATATAGTGGATTAACACCGGAACAAAAAGCATACGTACCAGCTATGTTTACTGCTGCGTTAAACATTCAGACGAGTGTAAACACTGTTGTTAGAGATTTTGAAAATTATGTGAAACAGACTTGTAATTCTAGCGCTGTTGTCGATAACAAATTAAAGATACAAAACGTAATTATAGATGAATGTTACGGAGCCCCAGGATCTCCAACAAATTTGGAATTTATTAATACAGGATCTAGCAAAGGAAATTGTGCCATTAAGGCGTTGATGCAATTGACTACTAAGGCCACTACTCAAATAGCACCTAGACAAGTTGCTGGTACAGGAGTTCAGTTTTATATGATTGTTATCGGTGTTATAATATTGGCAGCGTTGTTTATGTACTATGCCAAGCGTATGCTGTTCACATCCACCAATGATAAAATCAAACTTATTTTAGCCAATAAGGAAAACGTCCATTGGACTACTTACATGGACACATTCTTTAGAACTTCTCCGATGATTATTGCTACCACGGATATACAAAACTGAAAATATATTGATAATATTTTAATAGATTAACATGGAAGTTATCGCTGATCGTCTAGACGATATAGTGAAACAAAATATAGCGGATGAAAAATTTGTAGATTTTGTTATACACGGTCTAGAGCATCAATGTCCTGCTATACTTCGACCATTAATTAGGTTGTTTATTGATATACTATTATTTGTTATAGTAATTTATATTTTTACGGTACGTCTAGTAAGTAGAAATTATCAAATATTGTTGGTGTTGGTGGCGCTAGTCATCACATTAACTATTTTTTTATTACTTTATACTATAATAGTACTAGACTGACTTCTAACAAACATCTCACCTGCCATAAATAAATGCTTGATATTAAAGTCTTCTATTTCTAACACTATTCCATCTGTGGAAAATAATACTCTGACATTATCGCTAATTGATACATCGGTAAGTGATATGCCTATAAAGTAATAATCTTCTTTGGGCACATATACCAGTGTACCAGGTTCTAACAACCTATTTACTGGTGCTCCTGTAGCATACTTTTTTTTTACCTTGAGAATATCCATTGTTTGCTTGGTCAATAGTGATATGTGATTTTTTATCAACCACTCAAAAAAGTAATTGGAGTGTTCATATCCTCTACGGGCTATTGTCTCATGACCGTGTATGAAATTTAAGTAACACGACTGTGGTAGATTTGTTCTATAGAGCCGGTTGCCGCAAATAGATAGAACTACCAATATGTCTGTACAAATGTTAAACATTAATTGATTAACAGAAAAAACAATGTTCGTTCTGGGAATAGAAACCAGATTAAAACAAAATTCATTAGAATATATGCCACGTTTATACATGGAATATAAAATAACTACAGTTTGAAAAATAACAGTATCATTTAAACATTTAACTTGCGGGGTTAATCTCACAACTTTACTGTTTTTGAACTGTTCAAAATATAGCATAGATCCATGAGAAATACGTTTAGCCGCCTTTAATAGAGGAAATCCAACCGCCTTTCTGGATCTCACCAACGACGATAGTTCTGACCAGCAACTCATTTCTTCATCATCCACCTGTTTTAACATATAATAGGCAGGAGATAGATATCCATCATTGCAATATTCCTTCTCGTAGGCACACAATCTAATATTGATAAAATCTCCATTCTCTTCTCTGTATTTATTATCTTGTCTCGGTGGCTGATTAGGCTGTGGTCTATCGTTGTTGAATCTATTTTGGTCATTAAATCTTTCATTTCTTCCTGGTATATTTCTATCACCTCGTTTGGTTGGATTTTTGTCTATATTATCGTTTGTAACATCGGTACGGGTATTCATTTATCACAAAAAAAACTTCTCTAAATGAGTCTACTACTAGAAAACCTCATCGAAGAAGATACCATATTTTTTGCAGGAAGTATATCTGAGTATGATGATTTACAAATGGTTATTGCTGGTGCAAAATCCAAATTTCCAAGATCTATGCTTTCTATTTTTAATATAGTACCTAGAACGATGTCAAAATATGAGTTGGAGTTGATTCATAACGAGAATATCACAGGGGCAATGTTTACCACAATGTATAATATAAGAAACAATTTGGGTCTAGGCGATGATAAACTAACTATTGAAGCCATTGAAAACTATTTCTTGGATCCTAACAATGAGGTTATGCCTCTTATCATTAATAATACGGATATGACTACCGTCATTCCTAAAAAAAGTGGTAGGAGAAAGAATAAGAACATGGTTATCTTCCGTCAAGGATCATCACCTATCTTGTGTATTTTCGAAACTCGTAAAAAGATTAATATTTATAAAGAAAATATGGAATCCGTATCGACTAAGTATACACCTATCGGAGACAACAAGGCTTTGATATCTAAATATGCGGGAATTAATATCCTGAATGTGTATTCTCCTTCCACGTCCATGAGATTGAATGCCATTTACGGATTCACCAATAAAAATAAACTAGAGAAACTTAGTACTAATAAGGAACTAGAATCGTATAGTTCTAGCCCTCTTCAAGAACCCATTAGGTTAAATGATTTTCTGGGACTATTGGAATGTGTTAAAAAGAATATTCCTCTAACAGATATTCCGACAAAGGATTGATTACTATAAATGGAGAATGTTCCTAATGTATACTTTAATCCTGTGTTTATAGAGCCCACGTTTAAACATTCTTTATTAAGTGTTTATAAACACAGATTAATAGTTTTATTTGAAGTATTCGTTGTATTCATTCTAATATATGTATTTTTTAGATCTGAATTAAATATGTTCTTCATGCCTAAACGAAAAATACCCGATCCTATTGATAGATTACGACGTGCTAATCTAGCGTGTGAAGACGATAAATTAATGATCTATGGATTACCATGGATAACAACTCAAACATCTGCGTTATCAATAAATAGTAAACCGATAGTGTATAAAGATTGTGCAAAGCTTTTGCGATCAATAAATGGATCACAACCAGTATCTCTTAACGATGTTCTTCGCAGATGATGATTCATTTTTTAAGTATTTTGCTAGTCAAGATGATGAATCTTCATTATCTGATATATTGCAAATCACTCAATATCTAGACTTTCTGTTATTATTATTGATCCAATCAAAAAATAAATTAGAAGCTGTGGGTCATTGTTATGAATCTCTTTCAGAGGAATACAGACAATTGACAAAATTCACAGACTCTCAAGATTTTAAAAAACTGTTTAACAAGGTCCCTATTGTTACAGATGGAAGGGTCAAACTTAATAAAGGATATTTGTTCGACTTTGTGATTAGTTTGATGCGATTCAAAAAAGAATCAGCTCTAGCTACCACCGCAATAGATCCTGTTAGATACATAGATCCTCGTCGTGATATCGCATTTTCTAACGTGATGGATATATTAAAGTCGAATAAAGTTGAAAAATAATTAATTCTTTATTGTTATCATGAACGGCGGACATATTCAGTTGATAATCGGCCCCATGTTTTCAGGTAAAAGTACAGAATTAATTAGACGAGTTAGACGTTATCAAATAGCTCAATATAAATGTGTGACTATAAAATATTCTAACGATAATAGATACGGAACGGGACTATGGACACATGATAAGAATAATTTTGCAGCATTGGAAGTAACTAAACTATGTGATGTCTTGGAAGCAATTACAGATTTCTCCGTGATAGGTATAGATGAAGGACAGTTCTTTCCAGACATTGTTGAATTCTGTGAGCGTATGGCAAACGAAGGAAAAATAGTTATAGTAGCCGCGCTCGATGGGACATTTCAACGTAGACCGTTTAATAATATTTTGAATCTTATTCCATTATCTGAAATGGTGGTAAAACTAACTGCAGTGTGTATGAAATGCTTTAAGGAGGCTTCCTTTTCTAAACGATTAGGTACAGAAACCGAGATAGAAATAATAGGAGGTAATGATATGTATCAATCTGTGTGTAGAAAGTGTTACATCGACTCATAATATTATATTTTTTATCTAAAAAACTAAAAATAAACATTGATTAAATTTTAATATAATACTTAAAAATGGATGTTGTGTCGTTAGATAAACCGTTTATGTATTTTGAGGAAATTGATAATGAGTTAGATTACGAACCAGAAAGTGCAAATGAGGTCGCAAAAAAACTGCCGTATCAAGGACAGTTAAAACTATTACTAGGAGAATTATTTTTTCTTAGTAAGTTACAGCGACACGGTATATTAGATGGCGCCACCGTAGTGTATATAGGATCTGCTCCAGGTACACATATACGTTATTTGAGAGATCATTTCTATAATTTAGGAGTGATCATCAAATGGATGCTAATTGACGGCCGCCATCATGATCCTATTCTAAATGGATTGCGTGATGTGACTCTAGTGACTCGGTTTGTTGATGAGGAATATCTACGATCCATCAAAAAACAACTACATCCTTCTAAGATTATTTTAATTTCTGATGTGCGATCCAAACGAGGAGGAAATGAACCTAGTACTGCGGATTTACTAAGTAATTATGCTCTACAAAATGTCATGATTAGTATTTTAAACCCCGTGGCGTCTAGTCTTAAATGGAGATGCCCGTTTCCAGATCAATGGATCAAGGACTTTTATATCCCACACGGTAATAAAATGTTACAACCTTTTGCTCCTTCATATTCAGCTGAAATGAGATTATTAAGTATTTATACCGGTGAGAATATGAGACTGACTCGAGTTACCAAATCAGACGCTGTAAATTATGAAAAAAAGATGTATTACCTTAATAAGATAGTCCGCAACAAAGTAGTTATTAACTTTGATTATCCTAATCAGGAATATGACTATTTTCACATGTACTTTATGTTGAGGACCGTATACTGCAATAAAACATTTCCTACTACTAAAGCAAAGATACTATTTCTACAACAATCTATATTTCGTTTCTTAAATATTCCAACGACATCAACTGAAAAAGTTAGTCATGAACCAATACAACGTAAAATATCTAGCAAAGATTCTATGTCTAAAAACAGAAATAGCAAGAGATCCGTACGCGGTAATAAATAGAAACGTACTACTGAGATATACTACCGATATAGAGTATAATGATTTAGTTACTTTAATAACCGTTAGACATAAAATTGATTCTATGAAAACTGTGTTTCAGGTATTTAACGAATCATCCATAAATTATACTCCGGTTGATGATGATTATGGAGAACCAATCATTATAACATCGTATCTTCAAAAAGGTCATAACAAGTTTCCTGTAAATTTTCTATACATAGATGTGGTAATATCTGACTTATTTCCTAGCTTTGTTAGACTAGATACTACAGAAACTAATATAGTTAATAGTGTACTACAAACAGGCGATGGTAAAAAGACTCTTCGTCTTCCTAAAATGTTAGAGACGGAAATAGTTGTCAAGATTCTCTATCGTCCTAATATACCATTAAAAATTGTTAGATTTTTCCGCAATAACATGGTAACTGGAGTAGAGATAGCCGATAGATCTGTTATTTCAGTCGCTGATTAATCAATTAGTAGAGATGAGATAAGAACATTATAATAATCAATAATATATCTTATATCTGTTTAGAAAAATGCTAATATTAAAATAGCTAACGCTAGTAATCCAATCGGAAGCCATTTGATATCTATAATAGGGTATCTAATTTCCTGATTCAGATAGCGTACGGCTATATTCTCGGTAGCTACTCGTTTGGAATCACAGACATTATTTACATCTAATTTACTATCTGTAATGGAAACGTTTCCCAATGAAATGGTACAATCAGATACATTACATCTTGATATATTTTTTTTTAAAGAGGCTGGTAACAACGCATCGCTTCGTTTACATGGCTCGTACCAACAATAATAGGGTAATCTTGTATCTATTCCTATCCGTACTATACTTTTATCAGGATAAATACATTTACATCGTATATCGTCTTTGTTAGTATCACAGAATGCATAAATTTGTTCGTCCGTCATGATAAAAATTTAAAGTGTAAATATAACTATTATTTTTATAGTTATAATAAAAAGGGAAATTTGATTGTATACCTTCGGTTCTTTAAAAGAAACTGACTTGATAAAAATGGCTGTAATCTCTAAGGTTACGTATAGTCTATACGATCAAAAAGAGATTAATGCCACAGATATTATCATTAGTCATATTAAAAATGACGACGATATCGGTACCGTTAAAGATGGTAGACTAGGTGCTATGGATGGGGCATTATGTAAAACTTGTGGGAAAACGGAATTGGAATGTTTCGGTCACTGGGGTAAAGTAAGTATTTATAAAACTCATATAGTTAAGCCTGAATTTATTTCAGAAATTATTCGTTTACTGAATCATATATGTATTCATTGCGGATTATTGCGTTCACGAGAACCGTATTCCGACGATATTAACCTAAAAGAGTTATCGGTACACGCTCTTAGGAGATTAAAGGATAAAATATTATCCAAGAAAAAGTCATGTTGGAACAGCGAATGTATGCAACCGTATCAAAAAATTACTTTTTCAAAGAAAAAGGTTTGTTTCGTCAACAAGTTGGATGATATTAACGTTCCTAATTCTCTCATCTATCAAAAGTTAATTTCTATTCATGAAAAGTTTTGGCCATTATTAGAAATTCATCAATATCCAGCTAACTTATTTTATACAGACTACTTTCCCATCCCTCCGTTGATTATTAGACCGGCTATTAGTTTTTGGATAGATAGTATACCCAAAGAGACAAATGAATTAACTTACTTATTAGGTATGATCGTTAAGAATTGTAACTTGAATGCTGATGAACAGGTTATCCAGAAGGCGGTAATAGAATACGATGATATTAAAATTATTTCTAATAACACTACCAGTATCAATTTATCATATATCACATCCGGCAAAAATAATATGATTAGAAGTTATATCGTCGCTCGGCGAAAAGATCAGACCGCTAGATCCGTAATTGGTCCCAGTACATCTATCACCGTTAATGAGGTAGGAATGCCCACATATATTAGAAATACACTTACAGAAAAGATATTTGTTAATGCCTTTACAGTGGATAAAGTTAAACAACTATTAGCATCAAACCAAGTTAAATTTTACTTTAATAAACGATTAAACCAATTAACAAGAATACGTCAAGGAAAGTTTATCAAAAATAAAATACATTTATTGCCTGGTGATTGGGTAGAAGTAGCTGTTCAAGAATATACAAGTATTATTTTTGGAAGACAACCGTCTCTACATAGATACAACGTCATCGCTTCATCTATCAGAGCTACCGAAGGAGATACTATCAAAATATCTCCCGGAATTGCCAACTCTCAAAATGCTGATTTTGACGGAGATGAAGAATGGATGATATTGGAGCAAAATCCTAAAGCCGTAGTTGAACAAAGTATTCTTATGTATCCGACAACGTTACTCAAACACGATATTCATGGAGCCCCCGTTTATGGATCTATTCAAGATGAAATCGTAGCAGCGTATTCATTGTTTAGGATACAAGATCTTTGTTTAGATGAAGTATTGAACATCTTGGGGAAATATGGAAGAGAGTTCGATCCTAAAGGTAAATGTAAATTCAGCGGTAAAGATATCTATACTTACTTGATAGGTGAAAAGATTAATTATCCGGGTCTCTTAAAGGATGGTGAAATTATTGCAAACGACGTAGATAGTAATTTTGTTGTAGCTATGAGGCATCTGTCATTGGCTGGACTCTTATCCGATCATAAATCGAACGTGGAAGGTATCAACTTTATTATCAAGTCATCTTATGTTTTTAAGAGATATCTATCTATATACGGTTTTGGGGTGACATTCAAAGATCTGAGACCAAATTCGACGTTCACTAATAAATTGGAGGCTATCAACGTAGAAAAAATAGAACTTATCAAAGAAGCATACGCCAAATATCTCAAAGATGTAAGAGACGGGAAAATAGTTCCATTATCTAAAGCTTTAGAGGCGGACTACTTGGAATCCATGTTATCCAACTTGACAAATCTTAATATCAGAGAGATAGAAGAACATATGAGACAAACGCTGATAGATGATCCAGATAATAACCTCCTGAAAATGGCCAAAGCGGGTTATAAAGTAAATCCCACAGAACTAATGTATATTCTAGGTACTTATGGACAACAGAGGATAGATGGCGAACCAGCAGAGACTCGAGTATTGGGTAGAGTCTTACCTTACTATCTTCCAGACTCTAAGGATCCAGAAGGAAGAGGTTATATTCTTAATTCTTTAACAAAAGGATTAACGGGTTCTCAATATTACTTTTTGATGCTGGTTGCAAGATCTCAATCTACTGATATTGTCTGTGAAACATCACGTACCGGAACACTGGCTAGAAAAATCATTAAAAAGATGGAGGATATGGTGGTCGACGGATACGGACAAGTAGTTATAGGTAATACGCTCATCAAGTACGCAGCCAATTATACCAAAATTCTAGGCTCAGTATGTAAACCTGTAGATCTTATCTATCCAGATGAGTCCATGACTTGGTATTTGGAAATTAGTGCTTTGTGGAATAAAATAAAACAGGGATTCGTTTACTCTCAGAAACAGAAACTTGCAAAGAAGACATTGGCGCCGTTTAATTTCCTAGTATTCGTCAAACCCACCACTGAGGATAATGCTATTAAGGTTAAGGATCTGTACGATATGATTCATAACGTCATTGATGATGTGAGAGAGAAATACTTCTTTACGGTATCTAATATAGATTTTATGGAGTATATATTCTTGACGCATCTTAATCCTTCTAGAATTAGAATTACAAAAGAAACGGCTATTACTATCTTTGAAAAGTTCTATGAAAAACTCAATTATACTCTAGGTGGTGGAACTCCTATTGGAATTATTTCTGCACAGGTATTGTCTGAGAAGTTTACACAACAAGCCCTGTCCAGTTTTCACACTACTGAAAAGAGTGGTGCTGTAAAACAAAAACTTGGTTTCAACGAGTTTAATAACTTGACTAATTTGAGTAAGAATAAGACCGAAATTATCACTCTGGTATCCGATGATATCTCTAAACTTCAATCTGTTAAGATTAATTTCGAATTTGTATGTTTGGGAGAATTAAATCCAGACATCACTCTTCGAAAAGAAACAGATAGATATGTAGTAGACATAATAGTCAATAGATTATACATCAAGAGAGCAGAAATAACCGAATTAGTCGTCGAATATATGATTGAACGATTTATCTCCTTTAGCGTCATTGTAAAGGAATGGGGTATGGAGACATTCATTGAGGACGAGGATAATATTAGATTTACTATCTACCTAAATTTCGTTGAACCGGAGGAATTGAATCTTAGTAAGTTTATGATGGTTCTTCCAGGTGCCGCCAACAAGGGCAAGATTAGTAAATTCAAGATTCCTATCTCTGACTATACGGGATATAACGACTTCAATCAAACAAAAAAGCTCAATAAGATGACTGTAGAACTCATGAATCTAAAAGAATTGGGTTCTTTCGATTTGGAGAACGTCAACGTGTATCCTGGAGTATGGAATACATACGATATCTTTGGTATTGAGGCCGCTCGTGGATACTTGTGCGAAGCCATGTTAAACACCTATGGAGAAGGTTTCGATTATCTGTACCAGCCTTGTGATCTTCTCGCTAGTTTACTATGTGCTAGTTACGAACCAGAATCAGTTAATAAATTCAAGTTCGGTGCAGCTAGTACTCTTAAGAGAGCTACGTTCGGAGATAATAAAGCATTGTTAAACGCGGCTCTTCATAAAAAGTCAGAACCTATTAACGATAATAGTAGCTGCCACTTTTTTAGCAAGGTCCCTAATATAGGAACTGGATATTACAAATACTTTATCGACTTGGGTCTTCTCATGAGAATGGAAAGGAAACTATCTGATAAGATATCTTCTCAAAAGATCAAGGAGATAGAAGAAACAGAAGACTTTTAATTCTTATCAATAACATATTTTTCTATGATCTGTCTTTTAAACGATGGATTTTCCACAAATGCGCCTCTCAAGTCCCTCATAGAATGATACACGTATAAAAAATATAGCATAGGTGATGACTCCTTATTTTTAGACATTAGATATGCCAAAATCATAGCCCCGCTTCTATTTACTCCTGCAACACAATGAACCAACACGGGCTCGTTTCGTTGATCACATTTAGATAAGAAGGCGGTCACGTCGTCAAAATATTTACTAATATCAGTAGTTGTATCATCTACCAACGGTATATGAATAATATTAATATTAGAGTTAGGTAATGTATATTTATCCATCGTCAAATTTAAAACATATTTGAACTTAACTTCAGATGATGGTGCATCCATAGCATTTTTATAATTTCCCAAATACACATTATTTGTTACTCTTGTCATTATAGTGGGAGATTTGGCTCTGTGCATATCTCCAGTTGAACGTAGTAGTAAGTATTTATACAAACTTTTCTTATCCATTTATAACGTACAAATGGATAAAACTACTTTATCAGTAAACGCATGCAATTTAGAATACGTTAGAGAAAAGGCTATAGTAGGCGTACAAGCAGCCAAGACATCAACACTTATATTTTTTGTTATTATATTGGCAATTAGTGCGCTATTACTCTGGTTTCAGACGTCTGATAATCCAGTCTTTAATGAATTAACGAGATATATGCGAATTAAAAATACGGTTAACGATTGGAAATCATTAACGGATAGCAAAACAAAATTAGAAAGCGATAGAGGTAGACTTCTAGCCGCTGGTAAGGATGATATATTCGAATTCAAATGTGTGGATTTCGGCGCCTATTTTATAGCTATGCGATTGGATAAGAAAACATATCTGCCGCAAGCTATTAGGCGAGGTACTGGAGACGCGTGGATGGTTAAAAAGGCGGCAAAAGTCGATCCATCTGCTCAACAATTTTGTCAGTATTTGATAAAACACAAGTCTAATAATGTTATTACTTGTGGTAATGAGATGTTAAATGAATTAGGTTATAGCGGTTATTTTATGTCACCGCATTGGTGTTCCGATCTTAGTAATATGGAATAAGTGTTAGATAAATGCGGTAACAAATGTTCCTGTAAGGAACCATAACAGTTTAGATTTAACATTAAAGATGAGCATAAACATAATAAACAAAATTACAATCAAACCTATAACATTAATATCAAACAATCCAAAAAATGAAATCAATGGAGTAGTAAACGTGTACATAACTCCTGGATAACGTTTAGCAGCTACCGTTCCTATTCTAGACCAAAAATTTGGTTTCATGGTTTCGAAGCGGTGTTCTGCAACAAGACGAGGATCGTGTTCTACATATTTGGCAGAGTTATCCATTATTTGCCTGTTAATCTTCATTTCGTTTTCGATTCTGGCTATTTCAAAATAAAATCCCGATGATAGACCTCCAGACTTTATAATTTCATCTACGATGTTCAGCGCCGTAGTAACTCTAATAATATAGGCGGATAAGCTAACATCATACCCTCCTGTATATGTAAATATGGCATGATCTTTGTCTATTACAAGCTCGGTTTTAACTTTATTTCCTGTAATAATTTCTCTCATCTGTAGGATATCTATTTTCTTGTCATGTATTGCCTTCAAGACGGGACGAAGAAACGTAATATCCTCAATAACGTTATCGTTTTCTATAATAACTACATATTCTACATTTTTATTTTCTAGCTCGGTAAAAAATTTAGAATCCCATAGGGCTAAATGTCTAGCGATATTTCTTTTCGTTTCCTCTGTACACATAGTGTTACAAAACCCTGAAAAGAAGTGAGTATACTTGTCATCATCTCTAATATTTCCTCCAGTCCATTGTATAAACACATAATCCTTGTAATGATCTGGATCATCATTGACTATCACAACATCTCTTTTTTCTTGCATAACTTCATTGTCCTTCACATCATCGAACTTCTGATCATTAATATGCTCATGAACATTAGGAAATGTTTCTGATGGAGGTCTATCAATAACTGGCACAACAATAACAGGAGTTTTCACCGCCGCCATTTAGTTATTGAAATTAATCATATACAACTCTCTAATACGAGTTATATTTTCGTCTATCCATTGTTTCACATTGACATATTTCGACAAAAAGATATAAAATGCGTATTCCAATGCTTCTCTGTTTAATGAATTACTAAAATATACAAACACGTCACTGTCTGGTAATAAATAATATCTTAGAATATTGTAACAATTTATTTTGTATTGCACATGTTCGTGATCTATGAGTTCTTCTTCAAATGGCATAGGATCTCCGAATCTGAAAACGTATAAATAGGAGTTAGAATAATAATATTTGAGAGTATTGGTAATGTATAAACTCTTTAGCGGTATAATTAGTTTTTTTCTCTCGATTTCTATTTTTAGATGTGATGGAAAAATGACTAATTTTGTAGCATTAGTATCATGAACTCTAATCAAAATCTTAATATCTTCGTCACATGTTAGCTCTTTGAAGTTTTTAAGAGATGCATCAGTTGGTTTTACAGATGGAGTAGGTGCAACAATTTTTTGTTTAATGCATGCATGTATTGGAGCCATTGTCTTAACTATAATGGTGCTTGTATCGAAAAACTTTAATGCGGATAACGGAAGCTCTTCGCCGCGACTTTCTACGTCGTAATTGGGTTCTAATGCCGATCTCTGAATGGATACTAGTTTTCTAAGTTCTAATGTAATTCTCTGAAAATGTAAATCCAATTCCTCCGGCATTATAGATGTGTATACATCGGTAAATAAAACTATAGTATCCAACGATCCCTTCTCGCAAATTCTAGTCTTAACCAAGAAATCGTATATAACTACGGAGATGGCGTATTTAAGAGTGGATTCTTCTACCGTTTTGTTCTTGGATTTCATATAAGAAACTATAAAGTCCGCACTACTGTTAAGAATGATCACTAACGCAACTATATAGTTCAAATTAAGCATCTTGGAAACATAAAATAACTCTGTAGATGATACTTGACTTTCGAATAAGTTTGCAGACAAACGAAGAAAGAACAGACCTCTCTTAATTTCAGAAGAAAACTTTTTTTCGTATTCCTGACGTCTAGAGTTTATATCAATAAGAAAGTTAAGAATTAGTCGGTTAATGTTGTATTTCATTACCCAAGTTTGAGATTTCATAATATTGTCAAAAGACATGATAATATTAAAGATAAAGCGCTGACTATGAACGAAATAGCTATATGGTTCGCTCAAGAATATAGTCTTGTTAAACGTGGAAACGATAACTGTATTTTTAATCACGTCAGCGGCATCTAAATTAAATATAGGTATATTTATTCCACACACTCTACAATATGCCACACCATCTTCATAATAAATAAATTCGTTAGCAAAATTATTAATTTTAGTGAAATAGTTAGCGTCAACTTTCATAGCTTCCTTCAATCTAATTTGATGCTCACATGGCGCGAATTCTACTCTAACATCCCTTTTCCATGCCTCAGGTTCATCGATCTCTATAATATCTAGTTTCTTGCGTTTCACAAACACAGGCTCGTCTCTCGCGATGAGATCTGTATAGTAACTATGTAAATGATAACTAGATAGAAAGATGTAGCTATATAGATGACGATCCTTTAAGAGAGGTATAATAACTTTACCCCAATCAGATAGACTGTTGTTATGGTCTTCGGAAAAAGAATTTTTATAAATTTTTCCAGTATTTTCTAAATATACGTACTTGATATCTAAGAAATCCTTAATAATAATAGGAATGGATAATCCGTCTATTTTATAAAGAAATACATATCGCATATTATACTTTTTTTTGGAAATTGGAATACCGATGTGTCTACATAAATACGCAAAGTCTAAATATTTTTTAGAGAATCTTAGTTGGTCCAAATTCTTTTCCAAGTACGGTAATAGATTTTTCATATTGAACGGTATCTTCTTGATCTCTGGTTCTAATTCCGCATTAAATGATGAAACTAAGTCACTATTTTTATAACTAACGATTACATCACCTCTAACATCATCATTTACCAGGATACTGATCTTCTTTTGTCGTAAATACATGTCTAATGTGTTAAAAAAAAGATCATACAAGTTATACGTCATTTCATCTGTAGTATTCTTGTCATTGAAGGATAAACTCGTACTAATCTCTTCTTTAACAGTCTGTTCAAATTTATATCCTATATATGAAAAAATAGCAACCAGTGTTTGATCATCCGCGTCAATATTCTGTTCTATCGTAGTGTATAACAATCTTATATCTTCTTCTGTGATAGTCGATACGTTATAAAGGTTGATAACGAAAATATTTTTATTTCGTGAAATAAAGTCATTGTAGGATTTTGGACTTATATTCGTGTCTAGTAGATATGATTTTATTTTTGGAATGATCTCAATTAAAATAGTCTCTTTAGAGTCCATTTAAAGTTACAAACAACTAGGAAATTGGTTTATGATGTATAATTTTTTTAGTTTTTATAGATTCTTTATTCTATACTTAAAAAATGAAAATAAATACAAAGGTTCTTGAGGGTTGTGTTAATTGAAAGCGATAAATAATCATAAATTATTTCATTATCGCGATATCCGTTAAGTTTGTATCGTAATGGCGTGGTCAATTACGAATAAAGCGGATACTAGTAGTTTCACAAAGATGGCTGAAATCAGAGCTCATCTAAGAAATAGCGCTGAAAATAAAGATAAAAACGAGGATATTTTCCCGGAAGATGTAATAATTCCATCTACTAAGCCCAAAACCAAACGAACCACTACTCCTCGTAAACCAGCGGCTACTAAAAGATCAACCAAAAAGGATAAAGAAAAGGAGGAAGTGGAAGAAGTAGTTATAGAGGAATATCATCAAACAACTGAAGAAAATTCTCCACCTCCGTCATCATCTCCTGGAGTCGGCGACATTGTAGAAAGCGTGGCCGCTGTAGAGCTCGATGATAGCGACGGGGATGATGAACCTATGGTACAAGTTGAAGCTGGTAAAGTAAATCATAGTGCTAGAAGCGATCTCTCTGACCTAAAGGTGGCTACCGACAATATCGTTAAAGATCTTAAGAAAATTATTACTAGAATCTCTGCAGTATCGACTGTTCTAGAGGATGTTCAAGCAGCTGGTATCTCTAGACAATTTACTTCTATGACTAAAGCTATTACAACACTATCTGATCTAGTCACCGAGGGAAAATCTAAAGTTGTTCGTAAAAAAGTTAAAACTTGTAAGAAGTAAATGCGTGCACTTTTTTATAAAGATGGTAAACTGTTTACCGATAATAATTTTTTAAATCCTGTATCAGACGATAATCCAGCGTATGAGGTTTTGCAACATGTTAAAATTCCTACTCATTTAACAGATGTAGTAGTATATGAACAAACGTGGGAAGAGGCATTAACTAGATTAATTTTTGTGGGAAGTGATTCAAAAGGACGTAGACAATACTTTTACGGAAAAATGCATATACAGAATCGCAATGCTAAAAGAGATCGTATTTTTGTTAGAGTATATAACGTTATGAAACGAATTAATTGTTTTATAAACAAAAATATAAAGAAATCGTCCACAGATTCCAATTATCAGTTGGCGGTTTTTATGTTAATGGAAACTATGTTTTTTATTAGATTTGGTAAAATGAAATATCTTAAGGAGAATGAAACAGTAGGGTTATTAACACTAAAAAATAAACACATAGAAATAAGTCCCGATGAAATAGTTATCAAGTTTGTAGGAAAGGACAAAGTTTCACATGAATTTGTTGTTCATAAGTCTAATAGACTATATAAACCGCTATTGAAACTGACTGATGATTCTAGTCCCGAAGAATTTCTGTTCAACAAACTAAGTGAACGAAAGGTATATGAATGTATCAAACAGTTTGGTATTAGAATCAAGGATCTCCGAACGTATGGAGTCAATTATACGTTTTTATATAATTTTTGGACAAATGTAAAGTCCGTATCTCCTCTTCCATCACCAAAAAAGTTGATAGCATTAACTATCAAACAAACTGCTGAAGTGGTAGGTCATACTCCATCAATTTCAAAAAGAGCTTATATGGCAACGACTATTTTAGAAATGGTAAAGGATAAAAATTTTTTAGACGTAGTATCTAAAACTACGTTCGATGAATTCCTATCTATAGTCGTAGATCACGTTAAATCATCTACGGATGGATGATAATAGATCTTTACACAAATAATTACAAGACCGATAAATGGAAATGGATAAACGGATGAAATCTCTCGCTATGACAGCTTTCTTCGGAGAGCTAAACACGTTAGATATTATGGCATTGATAATGTCTATATTTAAACACCATCCAAACAATACCATTTTTTCAGTGGATAAGGATGGTCAATTTATGATTGATTTCGAATACGATAATTATAAGGCTTCTCAATATTTGGATCTGACCCTCACTCCGATATCTGGAAATGAATGCAAGACTCACGCATCTAGTATAGCCGAACAATTGGCGTGTGTGGATATTATTAAAGAGGATATTAGCGAATATATCAAAACTACTCCCCGTCTTAAACGATTTATAAAAAAATACCGCAATAGATCATATACTCGTATCAGTCGAGATACAGAAAAGCTTAAAATAGCTCTAGCTAAAGGCATAGATTACGAATATATAAAAGACGCTTGTTAATAAGTAAATGAAAAAAAACTAGTCGTTTATAATAAAACACAATATGGATGCCAACATAGTATCATCTTCTACTATTGCGACGTATATAGACGCTTTAGCGAAGAATGCTTCAGAATTAGAACAGAGGTCTACCGCATACGAAATAAATAATGAATTGGAACTAGTATTTATTAAACCGCCATTGATTACGTTGACAAATGTAGTAAATATCTCCACGATTCAGGAATCGTTTATTCGATTTACCGTTACTAATAAGGAAGGTATCAAAATTAGAACTAAGATTCCATTATCTAAGGTACATGGTCTAGATGTAAAAAATGTGCAGTTGGTAGATGCTATAGATAACATAGTTTGGGAAAAGAAATCATTAGTGACGGAAAATCGTCTTCACAAAGAATGCTTGTTGAGACTATCAACAGAGGAACGTCATATATTTTTGGATTACAAGAAATATGGATCCTCTATCCGACTAGAATTAGTCAATCTTATTCAAGCAAAAACAAAAAACTTTACGATAGACTTTAAGCTAAAATATTTTCTAGGATCTGGCGCTCAATCTAAAAGTTCTTTATTGCACGCTATTAATCATCCAAAGTCAAGGCCTAATACATCTCTGGAAATAGAATTTACACCTAGAGACAATGAAACAGTTCCATATGATGAACTAATAAAGGAATTGACGACTCTCTCGCGTCATATATTTATGGCTTCTCCAGAGAATGTAATTCTTTCTCCACCTATTAACGCACCTATAAAGACTTTTATGTTGCCTAAACAAGATATAGTAGGTCTGGATCTGGAAAATCTATATGCCGTAACTAAGACTGACGGCATTCCTATAACTATCAGAGTTACATCAAAAGGGTTGTATTGTTATTTTACACATCTTGGTTATATTATTAGATATCCAGTTAAGAGAACAATAGATTCCGAAGTAGTAGTCTTTGGTGAGGCAGTTAAGGATAAGAACTGGACCGTATATCTCATTAAGCTAATAGAGCCCGTAAATGCAATCAGTGATAGACTAGAAGAAAGTAAGTATGTTGAATCTAAACTAGTGGATATTTGTGATCGGATAGTATTCAAGTCAAAGAAATACGAAGGTCCGTTTACTACAACTAGTGAAGTCGTCGATATGTTATCTACATATTTACCAAAGCAACCAGAAGGTGTTATTCTGTTCTATTCAAAGGGACCTAAATCTAACATTGATTTTAAAATCAAAAAGGAGAATACTATAGACCAAACTGCAAATGTAGTATTTAGGTACATGTCCAGTGAACCAATTATCTTTGGAGAGTCGTCTATCTTTATAGAGTATAAGAAATTTACCAACGATAAAGGCTTTCCTAAAGAATATGGTTCTGGTAAGATTGTGTTATATAACGGCGTTAATTATCTAAATAATATCTATTGTTTGGAATATATTAATACACATAATGAAGTGGGTATTAAGTCCGTTGTTGTACCTATTAAGTTTATAGCAGAATTCTTAGTCAATGGAGAAATACTTAAACCTAGAATCGATAAAACCATGAAATATATTAACTCAGAAGACTATTATGGAAATCAACATAATATCATAGTCGAACATTTAAGAGATCAAAGCATCAAAATAGGAGATGTCTTTAACGAGGATAAACTATCGGATGTTGGACATCAATACGCTGCCAACAACGATAAATTTAGATTAAATCCAGAAGTTAGTTATTTTACTAATAAACGAACTAGAGGGCCGTTGGGAATTTTATCAAACTACGTCAAGACTCTTCTTATTTCTATGTATTGTTCCAAAACATTTTTAGACGATTCCAACAAACGAAAGGTATTAGCGATTGATTTTGGAAACGGTGCTGACCTGGAAAAATACTTTTATGGAGAGATTGCGTTATTGGTAGCGACGGATCCGGATGCTGATGCTATAGCTAGAGGAAATGAAAGATACAACAAATTAAATTCTGGAATTAAAACCAAGTACTACAAATTTGACTACATTCAGGAAACTATTCGATCCGATACATTTGTCTCTAGTGTCAGAGAAGTATTCTATTTTGGAAAGTTTAATATCATTGACTGGCAGTTCGCTATTCATTATTCTTTTCATCCAAGACATTATGCTACAGTCATGAATAACTTATCCGAACTAACTGCTTCTGGAGGCAAGGTATTAATTACTACCATGGATGGAGACAAATTATCAAAATTAACCGATAAAAAGACTTTTATAATTCATAAGAATCTACCTAGTAGCGAAAACTATATGTCTGTAGAAAAAATAGCTGATGATAGAATAGTGGTATATAATCCATCAACAATGTCTACTCCAATGACTGAATACATTATCAAAAAGAACGATATAGTCAGAGTGTTTAACGAATACGGATTTGTTCTTGTAGATAATGTTGATTTCGCTACAATTATAGAACGAAGTAAAAAGTTTATTAATGGCGCATCTACAATGGAAGATAGACCGTCTACAAGAAACTTTTTCGAACTAAATAGAGGAGCCATTAAATGTGAAGGTTTAGATGTCGAAGACTTACTTAGTTACTATGTTGTTTATGTCTTTTCTAAGCGGTAAATAATAATATGGTATGGGTTCTGATATCCCCGTTCTAAATGCATTAAATAATTCCAATAGAGCGATTTTTGTTCCTATAGGACCTTCCAACTGTGGATACTCTGTATTATTAATAGATATATTAATACTTTTGTAGGGTAACAGAGGTTCTACGTCTTCTAAAAATAAAAGTTTTATAACATCTGGCCTGTTCATAAATAAAAACTTGGCGATTCTATATATACTCTTATTATCAAATCTAGCCATTGTCTTATAGATGTGAGCTACTGTAGGTGTACCATTTGATTTTCTTTCTAATACTATATATTTCTCTCGAAGAAGTTCTTGCAGATCATCTGGGAATAAAATACTACTGTTGAGTAAATCAGTTATTTTTTTTATATCGATATTGATGGACATTTTTATAGTTAAGGATAATAAGTATCCCAAAGTAGATAACGACGATAACGAAGTATTTATACTTTTAGGAAATCACAATGACTTTATCAGATCAAAATTAACAAAATTAAAGGAGCATGTATTTTTTTCTGAATATATTGTGACTCCAGATACATATGGATCTTTATGCGTCGAATTAAATGGGTCTAGTTTTCAGCACGGTGGTAGATATATAGAGGTGGAGGAATTTATAGATGCTGGAAGACAAGTTAGATGGTGTTCTACATCCAATCATATATCTGAAGATATACACACTGATAAATTTGTCATTTATGATATTTATACGTTTGATTCGTTCAAGAATAAACGATTGGTATTTGTACAGGTACCTCCATCATTAGGAGATGATAGCTATTTAACTAATCCGTTATTGTCTCCGTATTATCGTAATTCAGTAGCCAGACAAATGGTCAATGATATGATTTTTAATCAAGATTCATTTTTAAAATATTTATTAGAACATCTGATTAGAAGCCACTATAGAGTTTCTAAACATATAACAATAGTTAGATACAAGGATACCGAAGAATTAAATCTAACAAGAATATGTTATAATAGAGATAAGTTTAAGGCGTTTGTATTCGCTTGGTTTAACGGCGTTTCGGAAAATGAAAAGGTACTAGATACGTATAAAAAGGTATCTGATTTGATATAATGAATTCAGTGACTATATCACACGCACCATATACTATTACTTATCACGATGATTGGGAACCAGTAATGAGTCAATTGGTAGAGTTTTATAACGAAGTAGCCAGTTGGTTGCTACGCGACGAGACGTCGCCTATTCCTGATAAGTTCTTTATACAATTGAAACAGCCGCTTAGAAATAAACGAGTATGTGTGTGTGGTATAGATCCGTATCCAAAAGATGGAACTGGTGTACCGTTCGAATCACCAAATTTTACAAAAAAATCAATTAAGGAGATAGCTTCATCTATATCTAGATTAACCGGAGTAATTGATTATAAAGGTTATAACCTTAATATAATAGACGGGGTTATACCCTGGAATTATTACTTAAGTTGTAAATTAGGAGAAACAAAAAGTCACGCGATTTACTGGGATAAGATTTCCAAGTTACTGCTACAGCATATAACTAAACACGTTAGTGTTCTTTATTGTTTGGGTAAAACAGATTTCTCGAATATACGGGCAAAGTTAGAATCCCCGGTAACTACCATAGTGGGATATCATCCAGCGGCCAGAGACCACCAATTCGAGAAAGATCGATCATTTGAAATTATCAACGTTTTACTGGAATTAGACAACAAGACACCTATAAATTGGGCTCAAGGGTTTATTTATTAATGCTTTAGTGAAATTTTAACTTGTGTTCTAAATGGATGCGGCTATTAGAGGTAATGATGTTATCTTTGTTCTTAAGACTATAGGTGTCCCGTCAGCATGCAGACAAAATGAAGATCCAAGATTCGTAGAAGCATTTAAATGCGACGAGTTAGAAAGATATATTGATAATAATCCAGAATGTACACTATTCGAAAGTCTTAGGGATGAGGAAGCATACTCTATAGTCAGAATTTTCATGGATGTAGATTTAGACGCGTGTCTAGACGAAATAGATTATTTAACGGCTATTCAAGATTTTATTATCGAGGTGTCAAACTGTGTAGCTAGATTCGCATTTACAGAATGCGGTGCCATTCATGAAAATGTAATAAAATCCATGAGATCTAATTTTTCATTGACTAAGTCTACAAATAGAGATAAAACAAGTTTTCATATTATCTTTTTAGACACGTATACCACTATGGATACATTGATAGCTATGAAACGAACACTATTAGAATTAAGTAGATCATCTGAAAATCCACTAACAAGATCGATAGACACTGCCGTATATAGGAGAAAAACAACTCTTCGGGTTGTAGGTACTAGGAAAAATCCAAATTGCGACACTATTCATGTAATGCAACCACCTCACGATAATATAGAAGATTACCTATTCACTTACGTGGATATGAACAACAATAGTTATTACTTTTCTCTACAACGACGATTGGAGGATTTAGTTCCTGATAAGTTATGGGAACCAGGGTTTATTTCGTTCGAAGACGCTATAAAAAGAGTTTCAAAAATATTCATTAATTCTATAATAAACTTTAATGATCTCGATGAAAATAATTTTACAACGGTACCACTGGTCATAGATTATGTAACACCTTGTGCATTATGTAAAAAACGATCGCATAAACATCCGCATCAACTATCGTTGGAAAATGGTGCTATTAGAATTTACAAAACTGGTAATCCACATAGTTGTAAAGTTAAAATTGTTCCGTTGGATGGTAATAAACTGTTTAATATTGCACAAAGAATTTTAGACACTAACTCTGTTTTATTAACCGAACGAGGAGACCATATAGTTTGGATTAATAATTCATGGAAATTTAACAGCGAAGAACCCTTGATAACAAAACTAATTCTATCAATAAGACATCAACTACCTAAGGAATATTCAAGCGAATTACTCTGTCCGAGGAAACGAAAGACTGTAGAAGCTAACATACGAGACATGTTAGTAGATTCAGTAGAGACCGATACCTATCCGGATAAACTTCCGTTTAAAAATGGTGTATTGGACCTGGTAGACGGAATGTTTTACTCTGGAGATGATGCTAAAAAATATACGTGTACTGTATCGACCGGATTTAAATTTGACGATACAAAATTCGTCGAAGACAGTCCAGAAATGGAAGAGTTAATGAATATCATTAACGATATCCAACCATTAACGGATGAAAATAAGAAAAATAGAGAGCTGTATGAAAAAACATTATCTAGTTGTTTATGTGGTGCTACCAAAGGATGTTTAACATTCTTTTTTGGAGAAACCGCAACTGGGAAGTCGACAACCAAACGTTTGTTAAAGTCTGCTATCGGTGACCTGTTTGTCGAGACGGGTCAAACAATTTTAACAGATGTATTGGATAAAGGACCTAATCCATTTATCGCTAATATGCATTTAAAAAGATCTGTATTCTGTAGCGAACTACCTGATTTTGCATGTAGTGGATCAAAGAAAATTAGATCTGATAATATTAAAAAGTTGACAGAACCTTGTGTCATTGGAAGACCGTGTTTCTCCAATAAAATTAATAATAGAAACCATGCGACAATCATTATCGATACTAATTACAAACCTGTCTTTGATAGGATAGATAACGCATTAATGAGAAGAATTGCCGTCGTGCGATTCAGAACACACTTTTCTCAACCTTCTGGTAGAGAGGCTGCTGAAAATAATGACGCGTACGATAAAGTCAAACTATTAGACGAGGGATTAGATGGTAAAATACAGAATAATAGATATAGATTCGCATTTCTATACTTGTTGGTTAAATGGTACAAAAAATATCATATTCCTATTATGAAACTATATCCTACACCGGAAGAGATTCCGGACTTTGCATTCTATCTCAAAATAGGTACTCTGTTGGTATCTAGCTCTGTAAAGCATATTCCATTAATGACGGACCTCTCCAAAAAGGGATATATATTGTACGATAATGTGGTTACTCTTCCGTTGACTACTTTCCAACAGAAAATATCCAAGTATTTTAATTCTAGACTATTTGGACACGATATAGAGAGCTTCATCAATAGACATAAGAAATTTGCCAATGTTAGTGATGAATATCTGCAATATATATTCATAGAGGATATTTCATCTCCGTAAATATATGCCATATATTTATAGAATATATCACATATCTAAATGAATACCGGAATCATAGATTTATTTGATAATCATGTTGATAGTATACCAACTATATTACCTCATCAGTTAGCTACTTTAGATTATCTAGTTAGAACTATCATAGATGAGAACAGAAGCGTGTTATTGTTCCATATTATGGGATCGGGTAAAACAATAATCGCTTTGTTGTTCGCCTTGGTAGCTTCCAGATTTAAAAAGGTTTACATTTTAGTACCGAACATCAACATCTTAAAAATTTTCAATTATAATATGGGTGTAGCTATGAACTTGTTTAATGACGAATTCATAGCTGAGAATATCTTTATTCATTCCACAACAAGTTTTTATTCTCTTAATTATAACGATAACGTCATTAATTATAACGGATTAAGTCGCTACAATAACTCTATTTTTATCGTTGATGAGGCACATAATATTTTTGGGAATAATACTGGAGAACTTATGACCGTGATAAAAAATAAAAACAAGATTCCTTTTCTACTATTGTCTGGATCTCCCATTACTAACACACCTAATACGCTGGGTCATATTATAGATTTAATGTCCGAAGAGACGATAGATTTTGGTGAGATTATTAGTCGTGGTAAGAAAGTAATTCAGACACTTCTTAACGAACGCGGAGTGAATGTACTCAAGGATTTGCTTAAAGGAAGAATATCATATTACGAAATGCCGGACAAAGATCTACCAACAATAAGATATCACGGACGTAAATTTCTAGATACTCGAGTAGTATATTGTCACATGTCTAAACTTCAAGAGAAAGATTATATGATTACTAGACGGCAGCTATGTTATCATGAAATGTTTGATAAAAATATGTATAACGTGTCAATGGCAGTATTGGGACAACTTAATCTGATGAATAATTTAGATACGTTATTTCAGGAACAGGATAAGGAATTGTACCCAAATCTGAAAATAAATAATGGAGTGTTATACGGTGAAGAATTGGTAACGTTAAACATTAGTTCCAAATTTAAGTACTTTATCAATCGGATACAGACACTCAAGGGAAAACACTTTATATACTTCTCTAATTCTACATATGGTGGATTGGTAATTAAATATATCATGCTCAGTAATGGATATTCTGAATATAATGGTTCTCAGGGAACTAATCCACATATGATAAACGGCAAACCAAAAACATTTGCTATCGTTACTAGTAAAATGAAATCGTCTTTAGAGGATCTATTAGATGTGTATAATTCTCCTGAAAACGATGATGGCAATCAATTGATGTTTTTGTTTTCGTCAAACATTATGTCTGAATCCTATACTCTGAAAGAGGTAAGGCATATTTGGTTTATGACTATCCCGGATACTTTTTCTCAATACAACCAAATTCTTGGACGATCTATTAGAAAATTCTCTTACGTCGATATTTCTGAACCCGTTAATGTATATCTTTTAGCAGCCGTATATTCAGATTTCAATGACGAAGTGACGTCATTAAACGATTATACACAGGATGAATTGATTAATGTTTTACCCTTTGACATCAAAAAGCTGTTGTATCTAAAATTTAAGACTAAAGAAACGAATAGAATATACTCTATTCTTCAAGAGATGTCTGAAACGTATTCTCTTCCACCACATCCATCAATTGTAAAAGTTTTATTGGGAGAATTGGTCAGACAATTTTTTTATAATAATTCTCGTATTAAGTATAACGACTCCAAGTTACTTAAAATGGTTACATCAGTTATAAAAAATAAAGAAGACGCTAGGAATTACATAGATGATATTGTAAACGGTCACTTCTTTGTATCGAATAAAGTATTTGATAAATCTCTTTTATACAAATACGAAAACGATATTATTACAGTACCGTTTAGACTTTCCTACGAACCATTTGTTTGGGGAGTTAACTTTCGTAAAGAATATAATGTGGTATCTTCTCCATAAAACTGATGAGATATATAAAGAAATAAATGTCGAGCTTTGTTACCAATGGATATCTTCCAGTTACATTGGAACCACATGAGTTGACGTTAGACATAAAAACTAATATTAGGAATGCCGTATATAAGGCGTATCTCCATAGAGAAATTAGTGGTAAAATGGCCAAGAAAATAGAAATTCGTGAAGACGTGGAATTACCTCTCGGTGAAATAGTTAATAATTCTGTAGTTATAAACGTTCCGTGTGTAATAACCTACGCATATTATCACGTTGGGGATATAGTCAGAGGAACATTAAACATCGAAGATGAATCAAATGTAACTATTCAATGTGGAGATTTAATCTGTAAACTAAGTAGAGATTCGGGTACTGTATCATTTAGCGATTCAAAGTACTGCTTTTTTCGAAATGGTAATGCGTATGATAACGGCATCGAAGTCTCCGCCGTTCTAATGGAGGCTCAACAAGGTACCGAATCTAGTTTTGTTTTTCTCGCGAATATCGTTGACTCATAAGAAAGAGAATAGCGGTGAGTATAAATACGAATACTATGGCAATAATTGCGAATGTTTTATTCCCTTCGATATATTTTTGATAATATGAAAAACATGCCTCTCTCAAATCAGACAACCATTTCATAAAATAGTTCTCTCGCACTGGTGAGGTGGTTGCAGCTCGTATAATCTCCCCAGAATAATATACTTGCGTGTCGTCGTTCAATTTATACGGATTTCTATAATTCTCTGTTATATAATGAGGTTTACCCTCATGATTAGACGACGACAATAGTGTTCTGAATTTAGATAGTTGATCAGAATGAATGTTTATTGGTGTTGGAAAAATTATCCATGCTGCGTCTGCAGAGTGGTTGATAGTTGTTCCTAGATATGTAAAATAATCCAACGTACTAGGTAGCAAATTGTCTAGATAAAATACTGAATCAAATGGCGCAGACATATTAGCGGATCTAATGGAATCCAATTGATTGACTATCTTTTGAAAATATACATTTTTATGATCTGATACTTGTAAGAATATAGCAATAATGATAATTCCATCATCGTGTTTTTTTGCCTCTTCATAAGAACTATATTTTTTCTTATTCCAATGAACCAGATTAATCTCTCCAGAGTATTTGTATACATCTATCAAGTGATTGGATCCATAATCGTCTTCCTTTCCCCAATATATATGTATTGTTGATAACACATATTCATTGGGGAGAAACCCTCCACTTATATATCCTCCTTTAAAATTAATCCTTACTAGTTTTCCAGTATTCTGGATAGTGGTTGGTTTCGACTCATTATAATGTATGTCTAACGTCTTCAATCGCGCGTCAGAAATTGCTTTTTTAGTTTCTATATTAATAGGAGATAGTTGTTGAGGCATAGTAAAAATGAAATGATAACTGTCTAGAAATAGCTCTTAGTATGGGATTTACAATGGATGAGGAAGTGATATTTGAAACTCCTAGAGAATTAATATCTATTAAACGAATAAAAGATATTCCAAGATCAAAAGACACGCACGTGTTTGCTGCGTGTATAACAAGTGACGGATATCCGTTAATAGGAGCTAGAAGAACTTCATTCGCATTCCAGGCGATATTATCTCAACAAAATTCAGATTCTATCTTTAGAGTATCCACTAAACTATTACGGTTTATGTACTACAATGAACTAAGAGAAATCTTTAGACGGTTGAGAAAAGGTTCTATCAACAATATCGATCCTCACTTCGAAGAGTTAATATTATTGGGTGGTAAACTAGATAAAAAGGAATCTATTAAAGATTGTTTAAGAAGAGAATTAAAAGAGGAAAGTGATGAACATATAACAGTAAAAGAATTCGGAAATGTAATTCTAAAACTTACAACGAGTGATAAATTATTTAATAAAGTATATATAGGTTATTGCATGGCATGTTTTATTAATCAATCGTTGGAGGATTTATCACATACTAGTATTTACAATGTAGAAATTAGAAAGATTAAATCGTTAAATGATTGTATTAACGACGATAAATACGAATATCTGTCTTATATTTATAATATACTAATTAATAGTAAATGAGCTTTTACAGATCTAGTATAATTAGTCAGATTATTAAGTATAATAGACGACTAGCTAAGTCTATTATTTGCGAGGATGACTCTCAAATTATTACACTCACGGCATTCGTTAACCAATGCCTATGGTGTCATAAACGAGTATCCGTGTCCGCTATTTTATTAACTACTGATAACAAAATATTAGTATGTAACAGACGAGATAGTTTTCTCTATTCTGAAATAATTAGAACTAGAAACATGTATAGAAAGAAACGATTATTTCTGAATTATTCCAATTATTTGAACAAACAGGAAAGAAGTATACTATCGTCATTTTTTTCTCTAGATCCAGCTACTGCTGATAATGATAGAATAAACGCTATTTATCCGGGTGGTATACCCAAAAGGGGTGAGAACGTTCCAGAGTGTTTATCCAGGGAAATCAAAGAAGAAGTTAATATAGACAATTCTTTTGTATTCATAGACACTCGTTTTTTTATTCATGGTATCATAGAAGATACCATTATTAACAAATTTTTTGAGGTAATTTTCTTTGTTGGACGAATATCTCTAACGAGTGATCAAATTATTGATACCTTTAAAAGTAATCATGAAATAAAGGATCTAATATTTTTAGATCCAAATTCAGGTAATGGACTCCAATACGAAATTGCAAAATATGCTCTAGATACTGCAAAACTTAAATGTTACGGTCATAGAGGATGTTATTATGAATCATTAAAAAAATTAACTGAGGATGATTGATTAGAAAATATAAATTAATTTACCATCGTGTATTTTTATAACGGGATTGTCTGGCATATCATGTAGATAGTTACCGTCTACATCGTATACTCTACCATCTACGCCTTTAAATCCTCTATTTATTGATATTAATCTATTAGAATTGGAATACCAAATATTAGTACCCTCAATTAGTTTATTGGTAATATTTTTTTTAGACGATAGATCGATGGCTCTTGAAACCAAGGTTTTCCAACCGGACTCATTGTCTATCGGTGAGAAGTCTTTTTCATTAGCATGAATCCATTCTAATGATGTATGTTTAAACACTCTAAACAATTGTACAAATTCTTTTGATTTGTTTTGAATGATTTCAAATAGGTCTTCGTCTACAGTAGGCATACCATTAGATAATCTAGCCATTATAAAGTGCACGTTTACATATCTACGTTCTGGAGGAGTAAGAACGTGACTATTGAGACGAATGGCTCTTCCTACTATCTGACGAAGAGACGCCTCGTTCCATGTCATATCTAAAATGAAGATATCATTGATTGAGAAGAAACTAATACCCTCGCCTCCGCTAGAAGAGAATACGCATGTTTTAATGCATTCTCCGTTAGTGTTTGATTCTTGGTTAAACTCAGCCACCGCCTTGATTCTAGTATCTTTTGTTCTAGATGAGAACTCTATATTAGAGATACCAAAGACTTTGAAATATAGTAATAAGATTTCTATTCCTGACTGATTAACAAATGGTTCAAAGACTAGACATTTACCATGGGATGCTAATATTCCCAAACATACATCTATAAATTTGACGCTTTTCTCTTTTAATTCAGTAAATAGAGAGATATCAGCCGCAATAGCATCCCCTCCCAATAGTTCTCCCTTTTTAAAGGTGTCTAATGCGGATTTAGAAAATTCTCTATCTCTTAATGAATTTTTAAAATCATTATATAGGGTTGCTATCTCTTGTGCGTATTCTCCCGGATCACGATTTTGTCTTTCAGGAAAGCTATCGAATGTAAACGTAGTAGCCATACGTCTCAGAATTCTAAATGATGATATACCAGTTTTTATTTCTGCGAGTTTAGCCTTTTGATAAATCTCTTCTTGCTTTTTTGACATATTAACGTATCGCATTAATACTGTTTTCTTAGCGAATGATGCAGACCCTTCCACATCATCAAAAATAGAAAACTCGTTATTAACTATGTACGAACATAGGCCTCCTAGTTTGGAGACTAATTCTTTTTCATCGACTAGACGTTTATTCTCAAATAGCGATTGGTGTTGTAAGGATCCTGGTCGCAGTAAGTTAACCAACATGGTGAATTCTTGCACACTATTAACGATAGGTGTAGCCGATAAACAAATCATCTTATGGTTTTTTAACGCAATGGTCTTAGATAAAAAATTATATACTGACCGAGTAGGACGGATCTTACCATCTTCTTTGATTAATGATTTAGAAATGAAGTTATGACATTCATCAATGATGACGCATATTCTACTCTTGGAATTAATAGTTTTGATATTAGTAAAAAATTTATTTCTAAAATTTTGATCATCGTAATTAATAAAAATACAATCCTTCGTTATCTCTGGAGCGTATCTGAGTATAGTGTTTATCCAAGGATCTTCTATCAAAGCCTTTTTTACCAATAAGATAATTGCCCAATTCGTATAAATATCCTTAAGATGTTTGAGAATATATACAGTAGTCATTGTTTTACCGACACCTGTTTCATGGAACAATAAAAGAGAATGCATACTGTCTAATCCTAAGAAAACTCTTGCTACAAAATGTTGATAATCCTTGAGGCGTACTACGTCTGACCCCATCATTTCAACGGGCATATTAGTAGTTCTGCGTAAGGCATAATCGATATAGGCCGCGTGTGATTTACTCATTTATGAGTGATAAGTAATAACTATGTTTTAAAAATCACAGCAGTAGTTTAACTAGCCTTCTCTGATGTTTGTTTTCGATACTTTTTGAATCAGAAGTCATACTAGAATAAAGCAGCGAGTGAACGTAATAGAGAGCTTCGTATACTCTATTCGAAAACTCTAAGAACTTATTAATGAATTCCGTATCCACTGGATCGTTTAAAATACTAAATTGAACAGTGTTCACATCCTTCCAAGACGAAGACTTAGTGACGGACTTAACATGAGACATAAATAAATCCAAATTTTTTTTATAAACATCACTAGCCACCATAATGGCGCTATCTTTCAACCAACTATCGCTTACGCATTTTAACAGTCTAACATTTTTAAAGAGACTACAATATATTCTCATAGTATCGATTACACCTCTACCGAATAGAGTGGGAAGTTTAATAATACAATATTTTTCGTTTACAAAATCAAATAATGGTCGAAACACGTCGAAGGTTAACATCTTATAATCGCTAATGTATAGATTGTTTTCAGTGAGATGATTATTAGATTTAATAGCATCTCGTTCACGTTTGAACAGTTTATTGCGTGCGCTGAGGTCGGCAACTACGGCATCCGCTCTAGTACTCCTCCCATAATACTTTACGCTATTAATCTTTAAAATTTCATAGACTTTATCTAGATCGCTTTCTGGTAACATGATATCATGTGTAAAAAGTTTTAACATGTCGGTCGGCATTCTATTTAGATCATTAACTCTAGAAATCTGAAGAAAGTAATTAGCTCCATATTCCAGACTAGGTAATGGGCTTTTACCTAAAGACAAGTTAAGTTCTGGCAATGTTTCATAAAATGGAAGAAGGACATGTGTCCCCTCCCGGATATTTTTTACAATTTCATCCATTTACAACTCTATAGTTTGTTTTCATTATTATTAGTTATTATCTCCCATAATCTTGGTAATACTTACACCTTGATCATAAGATACCTTATACAGGTCATTACATACAACTACCAATTGTTTTTGTACATAATAGATTGGATGATTGATATCCATGGTGGAATAAACTACTCGAACAGATAGTTTATCTTTCCCCCTAGATACATTGGCCGTAATAGTTGTCGGCCTAAAGAATATCTTTGGTGTAAAGTTAAAAGTTAGGGTTCTTGTTCCATTATTGCTTTTTGTCAGTAGTTCGTTATAAATTCTCGAGATGGGCCCGTTCTCTGAATATAGAACATCATTTCCAAATCTAACTTCTAGTCTAGAAATAATATCGGTCTTATTTTTAAAATCTATTCCCTTGATGAATGGATCGTTAATAAACAAATCCTTGGCCTTTGATTCGGCTGATCTATTATCTCCGTTATAGACGTTACGTTGACTAGTCCAAAGACTTACAGGAATAGATGTATCGATGATGTTGATAGTATGTGATATGTGAGCAAAGACTGTTCTCTTGGTGGCGTCGCTATATGTTCCAGTAATGGCGGAAAACTTTTTAGAAATGTTATATATAAAAGAATTTTTTCGGGTTCCAAACATTAACAGATTAGTATGAAGATAAACACTCATATTATCAGGAACATTATCAATTTTTACATAAACATCGGCATCTTGAATAGAAACAACACCATCTTCTGGAACCTCTACGATCTCGGCAGATTCCGGATAACCAGTCGGTGGACCATCACTAACAATAACTAGATCATCCAACAATCTACTCACATATGCGTCTATATAATCTTTTTCATCTTGTGAGTACCCTGGATACGAAATAAATTTGTTATCAGTATTTCCATAATAAGGTTTAGTATAAACAGAGAGAGATGTTGCTGCATGAACTTCGGTTACTGTCGCCGTTGGTTGGTTTATTTGACCTATTACTCTCCTAGGTTTCTCTATAAATGATGGTTTAATTTGTACATTCTTAACCATATATCCAATAAAGCTCAATTCAGGAACATAAACAAATTCTTTGTTGAACGTTTCAAAGTCGAACGAAGAGTCACGAATAACGATATCGGATACTGGATTGAAGGTCACCGTTACGGTAATTTTTGAATCGGATAGTTTAAGACTACTGAATGTATCTTCCACATCAAACGGAGTTTTAATATAAACGTATACTGTAGATGGTTCTTTAATAGTGTCATTAGGAGTTAGGCCAATAGAAATATCATTAAGTTCACTAGAATATCCAGAATGTTTCAAAGCAATTGTATTATTGATACAATTATTATATAATTCTTCGCCCTCAATTTCCCAAATAACACCGTTACACGAAGAGACAGATACATGATTAATACATTTATATCCAACATATGGCACGTAACCGAATCTTCCCATACCTTTAACTTCTGGAAGTTCCAAACTCAGAACCAAATGATTAAGCGCAGTAATATACTGATCCCTAATTTCGAAGCTAGCGATAGCCTGATTGTCTGGCCCATCGTTTGTCATAACTCCGGATAGAGAAATATATTGCGGCATATATAAAGTTGGAATTTGACTATCAACTGCGAAGACATTAGACCGTTTAATAAAGTCATCCCCACCGATCAAAGAATTAATGATAGTATTATTCATTTTCTATTTAAAATGGAAAAAGCTTACAATAAACTCCGTAGAGAAATATCTATAATTTGTGAGTTTTCCTTAAAGTAACAGCTTCCGTAAACACCGTCTTTATCTCTTAGTAAGTTTATTGTATTTATGACCTTTTCCTTATCTTCATAGAATACTAAAGGCAATAAAGAAATTTTTGGTTCTTCTCTAAGAGCTACGTGAGACTTAACCATAGACGCCAACGAATCCCTACATATTTTAGAACAGAAATACCCAACTTCACCACCCTTGAATGTCTCAATACTAATAGGTCTAAAAACCAAATCTTGATTACAAAACCAACACTTATCAATTACACTATTTGTCTTAATAGACATATCTGCCATAGATTTATAATACTTTGGTAGTATACAAGCGAGTGCTTCTTCTTTAGCGGGCTTAAAGACTGCTTTAGGTGCTGAAATAACCACATCTGGAAGACTTACTCGCTTAGCCATTTAATTACGGAACTATTTTTTTATACTTCTAATGAACAAGTAGAAAACCTCTCATCTACAAAAACATACTCGTGTCCATAATCCTCTACCATAGTAACACGTTTTTTAGATCTCATATGTGCTAAAAAGTTTTCCCATACTAATTGGTTACTATTATTTTTCGTATAATTTTTAACAGTTTGAGGTTTTAGATTTTTAGTTACAGAAGTGATATCGAATATTTTATCCAAAAAGAATGAGTAATTAATTGTCTTAGAAGGAGTGTTTTCTTGGCAAAAGAATACCAAGTGCTTAAATATTTCTACTACTTCATTAATCTTTTCTGTACTCAGATTCAGTTTCTCATCTTTTACTTGATTGATTATTTCAAAGACTAACTTATAATCCTTTTTATTTATTCTCTCGTTAGCCTTAAGAAAACTAGATACAAAATTTGCATCTACATCATCCGTGGATATTTGATTTTTTTCCATGATATCCAATAGTTCCGAGATAATTTCTCCAGAACATTGATGAGACAATAATCTCCGCAATACATTTCTCAAATGAATAAGTTTATTAGACACGTGGAAGTTTGACTTTTTTTGTACCTTTGTACATTTTTGAAATACAGACTCGCAAAAAATACAATATTCATATCCTTGTTCAGATACTATACCGTTATGTCTACAACAGCTACATAATCGTAGATTCATGTTAACACTCTACGTATCTCGTCGTCCAATATTTTATATAAAAACATTTTATTTCTAGACGTTGTCAGAAAATCCTGTAATATTTTTAGTTTTTTTGGTTGTGAATAAAGTATCGCCCTAATAATATTGGTACCGTCTTCCGACAATATAGTAGTTAAATTATCCGAGCATGTAGAAGAACACCGCTTAGGCGGATTCAGTACAATGTTATATTTTTCGTACCAACTCATTTAAATATCATAATCTAAAATAGTTCTGTAATATGTCTAGCGCTAATATATTGATCATAATCCTGTGCATAAATTAAGATACAACAATGTCTTGAAATCATCGACATGGCTTCTTCCATAGTTAGAAGATCATCGTCAAAGTTAGCAACGTGATTCATCAACATTTGCTGTTTTGAGGCAGCAAATACTGAACCATCACCATTCAACCATTCATAAAAACCATCGTCTGAATCCATTGATAATTTCTTGTACTGGTTTTTGAGAGCTCGCATCAATCTAGCATTTCTAGCTCCCGGATTGAAAACAGAAAGAGGATCGTACATCCAAGGTCCATTTTCTGTAAATAGAATCGTATAATGTCCCTTCAAGAAGATATCAGACGATCCACAATCAAAGAATTGGTCTCCGAGTTTGTAACAGACTGCGGACTTTAACCTATACATGATACCGTTTAGCATGATTTCTGGTGATACGTCAATCGGAGTATCATCTATTAGAGATCTAAAGCCGGTGTAACATTCTCCGCCAAACATATTCTTATTCTGACGTCGTTCTACATAAAACATCATTGCTCCATTAACGATAACAGGTGAATGAACAGCACTACCCATCACATTAGTTCCCAATGGATCAATGTGTGTAACTCCAGAACATCTTCCATAGCCTATGTTAGGAGGAGCGAACACCACTCTTCCACTATTGCCATCGAATGCCATAGAATAAATATCCTTGGAATTGATAGAAATCGGACTGTCGGATGTTGTTATCATCTTCATAGGATTAACAACGATGTATGGTGCAGCCTGAAGTTTCATATCGTAACTGATGCCGTTCATAGGTCTAGCCACAGAAACCAACGTAGGTCTAAATCCAACTATAGACAAAATAGAAGCTAATATCTGTTCCTCATCTGTCATAACTTGAGAGCATCCAGTATGAATAATCTTCATTAGATGGGGATCTACCGCATCATCATCGTTACAATAAAAAATTCCCATTCTAATGTTCATAATTGCTTTTCTAATCATGGTATGAATGTTTGCTCTCTGAATCTCTGTGGAAATTAGATCTGATACACCTGTAATCACTATCGGATTATCCTCCGTAAGACGATTAACCAACAACATATAATTATAAGACTTTACTCTTCTAAATTCATAAAGTTGCTGGATTAGACTATATGTGTCTCCATGTACATACGCGTTCTCGAGCGCAGGAAGTTTAATACCGAATAGTGCCATCAGAATAGGATGAATGTAGTAATTAGTTTCTGGTTTTCTATAAATAAAAGACAAATCTTGTGAACTAGACATATCGGTAAAATGCATGGATTGGAATCGTGTAGTCGACAGAAGAATATGATGATTAGATGGAGAGTATATTTTATCTAACTCTTTGAGTTGGTCACCGATTCTAGGACTAGCTCGAGAATGAATAAGTACTAAGGGATGAGTACATTTCACAGAAACACTGGCGTTGTTCAACGTACTCTTTACATGGGAAAGGAGTTGAAATAGCTCGTTTCTATTTGTCCTGACAATATTTAGTTTATTCATAATATTAAGCATATCCTGAATAGTAAAGTTAGATGTGTCATACTTGTTAGTAGTTAGATATTTAGCAATTGCATTCCCATCATTTCTCAATCTCGTACTCCAATCATGTGTGGATGCTACTTCGTCGATGGAAACCATACAATCCTTTTTGATAGGCTGTTGAGATTGATCATTTCCTGTACGTTTAGGTTTGGTACGTTGATTTCTAGCCCCTGCTGATATAAAGTCATCGTCTACAATTTGGGATAATGAATTACATACACTACAAGACAAAGATTTATCAGAAGTGTGAATATGATCTTCATCTACCAAAGAAAGAGTTTGATTAGTATAACTAGATTTTAGTCCCGCGTTAGATGTTAAAAAAACATCGCTATTGACCACGGCTTCCATTATTTATATTCGTAGTTTTTACTCGAAAGCGTGATTTTAATATCCAATCTTATTACTTTTGGAATCGTTCAAAACCTTTGACTAGTTGTAGAATTTGATCTATTGCCCTACGCGTATACTCCCTTGCATCATATACGTTCGTCACCAGATCGTTTGTTTCGGCCTGAAGTTGACGCATATCTTTTTCAACACTCGACATGAGATCCTTAAGGGTCATATCGTCTAGATTTTGTTGAGATGCTGCTCCTGGATTTGGATTTTGTTGTGCTGTTGTACATACTGTACCACCAGTAGGTGTAGGAGTACATACAGTGGCCACAATAGGAGGTTGAAGAGGTGTAACCGTTGGAGTAGTACAAGAAATACTTCCATCCGATTGTTGTGTACATGTGGTTGTTGGTAACGTCTGAGAAGGTTGGGTAGATGGCGGTGTCGTCATCTTTTGATCTTTATTAAATTTAGAGATAATATCCTGAACAGTATTGCTCGGCGTCAACGCTGGAAGGAGTGTACTCGCCGGCGCATCAGTATCTGTAGACAACCAATCAAAAAGATTAGACATATCAGATGATGTATTAGTTTGTTGACGTGGTTTTAGTACAGGAGCAGTACTACTAGGTAGAAGAATAGGAGCCGGTGTAGGTGTCGGAACCGGCTGTGGAGTTATATGAATAGTTGGTTGTAGCGGTTGGGTAGGCTGTCTGCTGGCGGTCATCATATTATCTCTAGCTAGTTGTTCTCGCAACTGTCTTTGATAATACGACTCTTGAGACTTTAGTCCTATTTCAATCGCTTCATCCTTTTTCGTATCCGGATCCTTTTCTTCAGAATAATAGATTGACGACTTTGGTGTAGAGGATTCTGCCAGCCCCTGTGAGAACTTGTTAAAGAAGTCCATTTAAGGCTTTAAAATTGAATTGCGATTATAAGATTAAATGGCAGACACGGACGATATTATCGACTATGAATCCGATGATCTCACCGAATACGAGGATGATGAAGAAGATGGAGAGTCACTAGAAACTAGTGATATAGATCCCAAATCTTCTTATAAGATTGTAGAATCAACATCCACTCATATAGAAGATGCGCATTCCAATCTTAAACATATAGGGAATCATATATCTGCTCTTAAACGACGCTATACTAGACGTATAAGTCTATTTGAAATAGCGGGTATAATAGCAGAAAGCTATAACTTGCTTCAACGAGGAAGATTACCTCTAGTTTCAGAATTTTCTGACGAAACGATGAAGCAAAATATGCTACATGTAATTATACAAGAGATAGAGGAGGGTTCTTGTCCTATAGTCATCGAAAAGAACGGAGAATTGTTGTCGGTAAACGATTTTGATAAAGATGGTCTAAAATTCCATCTAGACTATATTATCAAAATTTGGAAACTTCAAAAACGATATTAGAATTTATACGAATATCGTTCTCTAAATGTCACAATCAAGTCTCTCATATTCAGCAGTTTATTGTCGTACTTTATATCGTGTTCATTAACGATATTTTGCAAAATAGTAATGATTCTATCTTCCTTCGATAGATATTCTTCAGAGATTATTGTCTTATATTCTTTCTTGTTATCCGATATGAATTTGATAAGACTTTGAACATTATTAATACCCGTCTGTTTAATTTTTTCTATAGATATTTTAGTTTTGGTAGATTCTATGGTGTCTGTTAATAGGCATCCAACATCGACATTCGACGTCAATTGTCTATAAATCAGAGTATAAATTTTAGAAATAACATTAGCAAATTGTTGTGCGTTGATGTCGTTATTCTGAAACAGTATGATTTTAGGTAGCATTTTCTTAACAAAGAGAACGTATTTATTGTTACTCAGTTGAACAGATGATATATCCAGATTACTAACGCATCTGATTCCATATACCAAACTTTCAGAAGAAATGGTGTACAATTGTTTGTATTCATTCAATGTCTCCTTTTCAGAAATTAGTTTAGAGTCGAATACTGCAATAATTTTCAAGAGATAGTTTTCATCAGATAAGATTTTATTTAGTGTAGATATGATAAAACTATTGTTTTGTTGGAGAACTTGATACGCCGCATTCTCTGTAGTCGACGCTCTCAAATGGGAAACAATCTCTATTATTTTTTTGGAATCGGATACTATATCTTCGGTATCTTGACGCAGTCTAGTATACATAGAGTTAAGAGAAATTAGAGTTTGTACATTAAGCAACATGTCTCTAAATGTGGCTACAAACTTTTCTTTTTCCACATCATCTAGTTTATTATATACCGATTTCACAACGGCACCAGATTTAAGGAACCAGAATGAAAAACTCTGATAACTACAATATTTCATCATAGTTACGATTTTATCATCTTCTATAGTTGGTGTGATAACACATACCTTTTTCTCCAAGACTGGAACCAACGTCATAAAAATGTTTAAATCAAAATCCATATCAACATCTGATGCGCTAAGACCAGTCTCGCGTTCAAGATTATCTTTACTAATGGTGACGAACTCATCGTATAGAACTCTAAGTTTGTCCATTATTTATTTACAGATTTAGTTGTTTAATTTATTTGTGCTCTTCCAGAGTTGGGATAGTATTTTTCTAACGTCGGTATTATATTATTAGGATCTACGTTCATATGTATCATAATATTAATCATCCACGTTTTGATAAATCTATCTTTAGCTTCTGAAATAACGTATTTAAACAAAGGAGAAAAATATTTAGTTACGGCATCAGACGCGATAACATTTTTTGTAAATGTAACGTATTTAGACGACAGATCTTCGTTAAAAAGTTTTCCATCTATGTAGAATCCATCGGTTGTTAACACCATTCCCGCGTCAGAGTGAATAGGAGTTTGAATAGTTTGTTTTGGAAATAGATCCTTCAATAACTTATAGTTGGGTGGGAAAAAATCGATTTTATCACTAGACTCTTTCTTTTTTACTATCATTACCTCATGAACTATTTCTTGAATGAGTATATGTATTTTCTTTCCTATATCGGTCGCGTTCATTGGAAAATATATCATGTCGTTAACTATAAGAATATTTTTATCCTCGTTTACAAACTGAATAATATCAGATATAGTTCGTAAACGAACTATATCATCACCAGCACAACATCTAACTATATGATATCCACTAGTTTCCTTTAGCCGTTTATTATCTTGTTCCATATTAGCAGTCATTCCATCATTTAAGAAGGCGTCAAAGATAATAGGGAGAAATGACATTTTGGATTCTGTTACGACTTTACCAAAATTAAGGATATACGGACTTACTATCTTTTTCTCAACGTCGATTTGATGAACACACGATGAAAATGTACTTCGATGAGATTGATCATGTAGAAAACAACAAGGGATACAATATTTCCGCATATCATGAAATATATTAAGAAATCCCACTTTATTATATTTCCCCAAAGGATCAATGCATGTAAACATTATACCGTTATCATTAATAAAGACTTCTTTCTCATCGGATCTGTAAAAGTTGTTACTGATTTTTTTCATTCCAGGATCTAGATAATTAATAATAATGGGTTTTCTATTCTTATTCTTTGTATTTTGACATATCCTAGACCAGTAAACAGTTTCCACTTTGGTAAAATCAGAAGACTTTTGAACGCTATTAAACATGGCATTAATGGCAATAACTAAAAATGTAAAATATTTTTCTATGTTAGGAATATGGTTTTTCACTTTAATAGATATATGGTTTTTTGCCAAAATGATAGATATTTTTTTATCCGATGATAGTAAAATATTATTAGTCGCCGTCTCTATAAAAATGAAGCTAGTCTCGATATCCAATTTTATTCTAGAATTGATAGGAGTCGCCAAATGTACCTTATACGTTATATCTCCCTTGATGCGTTCCATTTGTGTATCTATATCGGACACAAGATCTGTAAATAGTTTTACGTTATTAATCATCACGGTATCGCCATCGCTAGATAATGCTAATGTACTATCCAAGTCCCAAATGGAGAGATTTAACTGTTCATCGTTTAGAATAAAATGATTACCTGTCATATTAATAAAGTGTTCATCGTATCTAGATAACAACGACTTATAATTAATGTCCAAGTCTTGAACTCGCTGAATGATCTTTTTTAACCCAGTTAGTTTTAGATTGGTACGAAATATATTGTTAAACTTTGATTCTACAGTAATGTCCAAATCTAGTTGTGGAAATACTTCCATCAACATTGTTTCAAACTTGATAATATTATTATCTACATCTTCGTACGATCCAAATTCCGGAATAGATGTATCGCACGCTCTGGCCACCCAGATAACCAAAAAGTCACACGCTCCAGAATATACATTGTATAAAAAGCTATCGTTTTTTAGTAGTGTTTTTTTCTGAGTATATACGAAAGGATTAAAAATAGTATTATCAACGTAACTATATTCCAAATTATTCTTATGAGAATAGATAATAATATCGTCCTTAATATCTAACAAATTTCCTAAATATCCCTTTAATTGAGTCATTCGAAGCGTTAATAAAATATGTCTCTTAACTATTTCCGGCCGTTGTATATTTAAATGACTTCGTAAGAAATAATATATAGGCGACTTCTCATCTATGTAATCATATGGAGTGAGATATAGGGCTCGTTCTACCTCCTGCCCCTTACCCACCTGTAATACCAATTGCGGACTCACTATATATCGCATATTTATATCGTGGGGTAAAGTGAAAATCTACTACCGATGATGTAAGTCTTACAATGTTCGAACCAGTACCAGATCTTAATTTGGAGGCCTCCGTAGAACTAGGGGAGGTAAATATAGATCAAACAACACCTATGATAAAGGAGAATAGCGGTTTTATATCCCGTAGTAGACGTCTATTCGCCCATAGATCTAAGGATGATGAGAGAAAACTAGCACTACGATTCTTTTTACAAAGACTTTATTTTTTAGATCATAGAGAGATTCATTATTTGTTCAGATGCGTCGACGCTGTAAAAGACGTCACTATTACCAAAAAAAATAACATTATCGTGGCGCCTTATATAGCACTTTTAACTATCGCATCAAAAGGATGCAAACTTACAGAAACAATGATTGAAGCATTCTTTCCAGAACTATATAATGAACATAGTAAGAAATTCAAATTCAACTCTCAAGTATCCATCATCCAAGAAAAACTCGGATACCAGTCTGGAAACTATCACGTTTATGATTTTGAACCGTATTACTCTACAGTAGCTCTGGCTATTCGAGATGAACATTCATCTGGCATTTTTAATATCCGTCAAGAGAGTTATCTTGTAAGTTCATTATCTGAAATAACATATAGATTTTATCTAATTAATCTAAAATCTGATCTTGTTCAATGGAGTGCTAGTACGGGCGCTGTAATTAATCAAATGGTAAATACTGTATTGATTACAGTGTATGAAAAATTACAACTGGCCATAGAAAATGATTCACAATTTACATGTTCATTGGCTGTGGAATCAGAACTTCCAATAAAATTACTTAAAGATAGAAATGAATTATTTACAAAATTCATTAACGAGTTAAAAAAGACCAGTTCATTCAAGATAAGCAAACGTGATAAGGATACGCTATTAAAACATTTTACTTATGACTGGAGTTAGAATTTATAGACGACACATTTCGTTTATCATTGTTACTATTACTATCATTATTAGTATTCTTCTTGTCATCTTGTTCAGAAATATACAGCAATGCTATACCTAATACTAAATACATTATCATGCTTGCAATGGCTCTAACAACAACGAACCAAAATGAATTTGGTCGTAGCTTTTGTTCACAAAAATACATAAAGAAATGTCTACATAAATCTATGGCGCCATTGGCTACTTGAAATAGCGCCAGTCCTCCTACAGATTTTAATATAGCTGTATAACATGACATTTATTCATCATCAAAAGAGACAGAGTCACCATCTGTCATATTTAGATTTTTTTTCATGTGTTCAAAGTATCCTCTACTCATTTCATTATAATAGTTTATCATGCTTAGAATTTTAGGACGGATCAATGAGTAAGACTTGACTAGATCGTCAGTAGTAATTTGTGCATCATCTATTCTGCATCCGCTTCGTCGAATAATGTATAGCATCGCTTTGAGATTCTCCATAGCTATCAAGTCTTTATATAATGACATGGAAATATCTGTGAATGCTTTATACTTCTCCAACATCGATGCCTTAACATCATCACATACTTTAGCATTGAAAATACGTTCTATTGTGTAGATGGATGTAGCAAGATTTTTAAACAACAATGCCATCTTACATGATGATTGTCTCAAGTCTCCAATCGTTTGTTTAGAACGATTAGCTACAGAGTCCAATGCTTGGCTAACTAGCATATTATTATCTTTAGAAATTGTATTCTTCAATGAGGCGTTTATCATATCTGTGATTTCGTTAGTCATATTACAGTCTGACTGGGTTGTAATGTTATCCAACATATCACCTATGGATACGGTACACGTACCAGCATTTGTAATAATCCTATCTAAGATGTTGTATGGCATTGCGCAGAAAATATCTTCTCCTGTAATATCTCCACTCTCGATAAATCTACTCAGATTATTCTTAAATGCCTTATTCTCTGGAGAAAAGATATCAGTGTCCATCATTTCATTAATAGTATACGCAGAAAAGATACCACGAGTATCAATTCTATCCAAGATACTTATCGGTTCCGAGTCACAGATAATTGTTTCCTCTCCTTCGGGAGATCCTGCATAGAAATATCTAGGACAATAGTTTCTATACTGTCTGTAACTCTGATAATCTCTAAAGTCACTAACTGATACCATGAAATTGAGAAGATCAAACGCTGAAGTAATCAATTTTTCTGCCTCGTTTTTACTACAACTAGTTTTCATCAATGTAGTGACGATGTATTGTTTAGTTACTCTTGGTCTAATACTGATGATAGAGATATTATTGCTTCCCATAATGGATCTTCTAGTAGTCACCTTAAAGCCCATTGATGCGAATAGCAGATAGATAAAGTCTTGGTATGACTCCTTTCTAATATAGTACGGACTACCTTTGTCACCCAACTTTATACCCACATAAGCCATAACAACCTCTTTAATAGCCGTTTCATGAGGTTTATCAGCCATGAGCCTGAGTAGTTGAAAGAATCGCATGAATCCCGTCTCAGAAAGTCCTATATGCATGATAGATTTATCTTTCCTGGGAAACTCTCGTATAGTTATAGATGAAATACTCTTCAAAGTTTCTGAAATAAGATTAGTAACAGTCTTACCTCCGACTACTCTGGGTAACAAACATACTCTAATAGGTGTTTTCTCTGCGGAGATAATATCAGAAAGGATAGAGCAATAAGTAGTATTATTGTGATTATAAAGACCGAATACATAACAGGTAGAATTTATAAACATCATGTCCTGAAGGGTTTTAGACTTGTATTCCTCGTAATCTATACCGTCCCAAAACATGGATTTGGTAACTTTGATAGCCGTAGATCTTTGTTCCTTCGCTAACAGGTTAAAGAAATTAATAAAGAATTTGTTGTTTCTATTTATGTCCACAAATTGCACGTTTGGAAGCGCCACGGTTACATTCACTGCAGCATTTTGAGGATCGCGAGTATGAAGTACGATGTTATTGTTTACTGGTATATCTGGAAAGAAATCTACCAGTCTAGGAATAAGAGATTGATATCGCATAGAAATAGTAAAGTTTATAATCTCATCATTGAAGATTACTCTGTTACCATTGTAATAAATTGGTACTCTATCATAATCATCGACAAAGTACTGTTCATACATGATGAGATGTTTATATGTTGGCATAGTAGTGAGATCGACGTTTGGTAATGGCAATGTATTAAGATTAACTCCATAATGTCTAGCAGCATCTGCGATGTTATAAGTGATGTCAAAGCGGGGTTGATCTTGTGCTGTTATATATTGTCTAACACCTATAAGATTATCAAAATCTTGTCTGCTTAATACACCGTTAACAATTTTTGCCTTGAATTCTTTTATTGGTGCATTAATAACATCCTTATAGAGGATGTTAAACAAATAAGTATTATCAAAGTTAAGATCTGGGTATTTCTTTTCTGCTAGAACATCCATTGAGTCGGAGCCATCTGGTTTAATATAACCACCGATAAATCTAGCTCTGTATTCTGTATCCGTCAATCTAATATTAAGAAGGTGTTGAGTGAAAGGTGGAAGATCGTAAAAGCTGTGAGTATTAATAATAGGGTTAGTTTCCGAACTAATGTTAATTGGATGATTAATAATATTTATATTTCCAGCGTTAAGTGTAACATTAAACAGTTTTAATTCACGTGACGTGGTATCAATTAAATAATTAATGCCCAATTTGGATATAGTAGCCTGAAGCTCATCTTGTTTAGTTACGGATCCTAATGAGTTATTAAGAAATACATCGAACGGATGAACGAAGGTTGTTTTAAGTTGGTCACATACTTTGTAATCTAGACATAGATGTGGAAGAACGGTAGAAACTATACGAAATAGATATTCAGAGTCCTCTAATTGATCAAGAGTAACTATTGACTTAATAGGCATCATTTATTTAGTATTAAATGACGACCGTACCAGTGACAGATATACAAAACGACTTAATTACAGAGTTTTCAGAAGATAATTATCCATCTAACAAAAATTATGAAATAACTCTTCGCCAAATGTCTATTCTAACTCACGTTAACAACGTGGTAGATAGAGAACATAATGCCGCCGTAGTGTCATCTCCAGAGGAAATATCATCACAACTTAATGAAGATCTATTTCCAGATGATGATTCACCGGCCACTATTATCGAACGAGTACAACCTCATACTACTATTATTGACGATACGCCACCTCCTACTTTTCGTAGAGAGTTATTGATATCGGAACAACGTCAACAACGAGAAAAAAGATTTAATATTACAGTATCAAAAAATTCTGAAGCAATAATGGAATCTAGATCTATGATAACTTCTATGCCAACACAAACACCATCCTTGGGAGTAGTTTATGATAAAGATAAAAGAATTCAGATGCTAGAGGATGAAGTGGTTAATCTTAGAAATCAACGATCTAATACAAAATCATCTGATAATTTAGATAATTTTACCAGAATACTATTTGGTAAGACTCCGTATAAATCAACCGAAGTTAATAAGCGTATAGCCATCGTTAATTATGCAAATTTGAACGGGTCCCCCTTATCAGTCGAGGACTTGGATGTCTGTTCGGAGGATGAAATAGATAGAATCTATAAAACGATTAAACAATATCACGAAAGTAGAAAACGAAAAATTATCGTCACTAACGTGATTATTATTGTCATAAACATTATTGAGCAGGCATTGCTAAAACTCGGATTTGAAGAAATCAAAGGACTGAGTACCGATATCACTTCAGAAATTATCGATGTGGAGATCGGAGATGACTGCGATGCTGTAGCATCAAAACTAGGAATCGGTAACAGTCCGGTTCTTAATATTGTATTGTTTATACTCAAGATATTCGTTAAACGAATTAAAATTATTTAATTTAATACATTCCCATATCCAGACAACAATCGTCTGGATTAATCTGTTCCTGTCGTCTCATACCGGACGACATATTAATCTTTTTATTAGTGGGCATCTTTTTAGATGGTTTCTTTTTCCCAGCATTAACTGATTCGATACCTAGAAGATCGTGATTGATTTCTCCGACCATTCCACGAACTTCTAATTGGCCGTCTCTAACGGTACCATAAACTATTTTACCAGCATTAGTAACAGCTTGGACAATCTGACCATCCATTGCGTTGAATGATGTAGTTGCTGTTGTTCTACGTCTAGGAGCACCAGAGGTATTTTTAGAGCTCTTGGATGTTGATGTAGAAGACGAGGATTTTGATTTTGGTTTACATGTAATACATTTTGAACTCTTTGATTTTGTATCACATGCACCGGCAGTCACATCTGTTTGAGAATTAAGATTATTGTTGCCTCCTTTGACGGCTGCATCTCCACCGATCTGCGCTAGTAGATTTTTAAGCTGTGGTGTAATCTTATTAACTGTTTCAATATAATCATCGTAACTACTTCTAACGGCTAAATTTTTTTTATCCGCCATTTAGAAGCTAAAAATATTTTTATTTATGCAGAAGATTTAACTAGATTATACAATGAACTAATATGATCCTTTTCTAGATTATTTACGAACTTGGTATTTCTTGTTTCTGGAGGAGGAGAATTTAAATTCGGACTTGGATTCGGATTTTGTGGGTTCTTGATCTTATTATACAGCGTGTATAGGATGGTGACGGTAACTGCTACACAAATACCGATCAACAGAAGAATACCAATCATTTATTGACAATAACTTCACTATGATCAAGTATGTAATAATCATCTTTTCACTAAGTAAGTAGTAATAATGATTCAACAATGACACGATATATGGACGATAATAATTTAGTTCATGGAAATATCGCTATGATTGGTGTGAATGACTCCGCTAACTCTGTGGGGTGCACAGTGCTTTCCCCACATAGAATAAATTAGCATTCCGACTGTGATAATAATACCAAGTATAAACGCCATAATACTCAATACTTTCCATGTACGAGTGGGACTGGTAGACTTACTAAAGTCAATAAAGGCGAAGATACACGAAAGAATCAAAAGAATGATTCCAGCGATTAGCACGCCAGAAAAATAATTTCCAATCATAAGCATCATGTCCATTTAACTAATAAAAATTTTAAATCGCCGAATAAACAAAGTGGAATATAAACCATATAAAAACAATAGTTTGTACTGCAAAAATAATATCTATTTTTGTTTTCGAAGATATGGTAAAATTAAATAGTAGTACACAGCATGTTATAACTAACAGCAGCAACGGCTCGTAATTACTTATCATTTACTAGACGAAAAGGTGGTGGGATATTTTCTTGCTCAAATAATACGAATATATCACCCATCCATTTTATACGATGTTTATATACTCTAATCTTTAATAGATCTATAGATGACGGGTTTACCAATAATATAGATTTTATCGATTCATCTAATTTAAACCCTTCCTTAAACGTGAATGATCTATTATCTGGCATAATGATGACCCTACCTGATGAATCTGACAATGTACTGGGCCATGTAGAATAAATTATCAACGAATTATCGTCTACGAACATTTATATCATTTGTTTTAATTTTAGGACGTGAATAAATAGATATAAAATAGAAAATAACAGATATTACAACCAGTGTTATGGACGCACCCAACCATGTAGGCAGTTTTATTTTATCGTTTACTACAGGTTCTCCTGGATGTACGTCACCAACTGCAGACGTAGTTCTAGTACAATTAGACGTAAGTTCCGCTTGGGAATTTTTTAACGCTAAAGAGTTAACGTTGATCGTACACCCAACGTATTTACATCTAGTTCTTTGAACATCTTGATTATAATATAACCATTTTCTATCTCTAGATTCGTCAGTGCACTCATGTAACCAACATACCCTAGGTCCTAAATATTTATCTCCGGAATTAGATTTTGGATAATTCGCGCACCAACAATTTCTATTTCCTTTATGGTCGTTACAAAAGACGTATAATGCCGTATCCCCAAAAGTAAAATAATCAGGACGAATAATTCTAATAAACTCAGAACAATATCTCGCATCCATATGTTTGGAGCAAATATCGGAATAAGTAGACATAGCCGGTTTCCGTTTTACACGTAACCATTCTAAACAATTGGGGTTTCCAGGATCGTTTCTACAAAAACCAGTCATGAAATCGTCACAATGTTCTGTCTTGTAATTATTATTAAATATTTTTGGACAGTGTTTGGTATTTGTCTTAGAACAACATTTTGCCACGCTATCACTATCACCCAGGAGATAATCCTTTTTTATAAAATGACATCGTTGCCCGGATGCTATATAATCAGTAGCATATTTTAAATCCTTAATATATTCAGGAGTTACCTCGTTCTGATAATAGATTAATGATCCAGGACGAAATTTGAAAGAACTACATGGTTCTCCATGAATTAATACATATTGTTTAGCAAATTCAGGAACTATAAAACTACTACAATGATCTATCGACATACCATCTATCAAACAAAATTTGGGTTTAATTTCTCCTGGAGACGTTTCATAATAATACATATAACTTTCTTCGGCAAACCTAACAGCTCTATTATATTCAGGATAATTAAAATCTAATACCATATATTTGTCTCGTATATCTGCTATTCCTGTCTCTATTTTGATTCTATTAAGAGTAACAGCTGCCCCCATTCTTAATAATCATCAGTATTTAAACTGTTAAATGTTGGTATATCAACATCTATCTTATTTCCCGCAGTATAAGGTTTGTTGCAGGTATACTGTTCAGGAATGGGTACATTTATACTTCTTTTATAGTCCTGTCTTTCGATGTTCATCACAAATGCAAAGAACAGAATAAACAAAATAATGTAAGAAATAATATTAAATATCTGTGAATTCGTAAATACATTGATTGCCATAATAATTACAGCAGCTACAATACACACAATAGACATTCCCACAGTGTTGCCATTACCTCCACGATACATTTGAGTTACTAAGCAATAGGTAATAACTAAGCTAGTAAGAGGCAATAGAAAAGATGAGATAAATATCATCAATATAGAGATTAGAGGAGGGCTATATAGAGCCAAGACGAACAAAATCAAACCGAGTAACGTTCTAACATCATTATTTTTGAAGATTCCCAAATAATCATTCATTATTCCTCCATAATCGTTTTGCATCATACCCCCATCTTTAGGCATAAACGATTGCTGCTGTTCCTCTGTAAATAAATCTTTATCAAGCACTCCAGCACCCGCAGAGAAGTCATCAAGCATATTGTAATATCTTAAATAACTCATTTATATATTAAAAAATGTCACTATTAAAGATGGAGTATAATCTTTATGCCGAACTAAAAAAAATGACTTGTGGTCAGACCATAAGTCTTTTTAATGAAGACGGCGATTTCGTAGAAGTTGAACCAGGATCATCCTTTAAGTTTCTAATACCTAAGGGATTTTACTCCTCTCCTTGTGTAAAGACGAGTCTAGTATTCAAGACATTAACAACGACCGATAATAAAATTACTAGTATCAATCCAACAAATGCGCCAAAGTTATATCCTCTTCAACGCAAAGTCGTATCTGAAGTAGTTTCTAATATGAGGAAAATGATCGAATTAAAACGTCCTCTATACATCACTCTTCACTTGGCATGTGGATTTGGTAAGACTATTACCACGTGTTATCTTATGACCACACACGGCAGAAAAACCATCATTTGCGTACCCAATAAAATGTTAATACATCAATGGAAGACACAGGTAGAGGCAGTCGGATTGGAACATAAGATATCTATAGATGGAGTTAGTAGTCTATTAAAGGAACTAAAGACTCAAAGTCCGGATGTATTAATCGTAGTCAGTAGACATCTGACAAACGATGCATTTTGTAAATATATCAATAAGCATTATGATTTGTTTATCTTGGATGAATCACATACGTATAATCTGATGAACAATACAGCAGTTACAAGATTTTTAGCGTATTATCCTCCGATGATGTGTTATTTTTTAACTGCTACACCTAGACCAGCTAACCAAATTTATTGTAATAGTATTATTAATATTGCCAAGTTATCCGATCTAAAAAAAACTATCTATATAGTAGATAGTTTTTTTGAGCCATATTCCACAGACAATATTAGAAATATGGTAAAACGACTAGATGGACCATCTAATAAATATCATATATATACCGAGAAGTTATTATCTGTAGACGAGCCTAGAAACCAACTTATTCTTGATACCCTGGTAGAAGAATTCAAGTCAGGAACTATTAATAGAATTTTAGTTATTACTAAACTACGTGAACATATGGTATTCTTCTACAAACGATTATTAGATCTTTTCGGAGCAGAGGTTGTATTTATAGGAGACGCCCAAAATAGACGTACTCCAGATATGGTCAAATCGATTAAGGAACTAAATAGATTTATATTCGTATCCACCTTATTTTATTCCGGCACTGGTTTAGATATTCCGAGTTTGGATTCTTTGTTCATTTGCTCGGCAGTAATCAACAATATGCAAATAGAGCAATTACTAGGGAGGGTATGTCGAGAAACAGAACTATTAGATAGGACGGTATATGTATTTCCTAACACATCCATCAAAAAAATAAAGTACATGATAGGAAATTTCGTGCAACGAATTATTAGTCTGTCTGTAGATAAACTCGGATTTAAACAAGAAAGTTATCAGAAACATCAGGAATCTGAACCCGCTTCCGTACCAACATCCTCCAGAGAAGAACGTGTATTAAATAGAATATTTAACTCGCAAAATCGTTAAGAAGTTTAAGAGACGATCCACATGCTGAGCAGGCCAGTGTATTACCCCTCATAGTATTAATATAATCCAATGATACTTTTGTGATGTCGGAAATCTTAACCAATTTAGACTGACAGGCAGAACACGTCATACAATCATCATCGTCATCGATAACTGTAGTCTTGGGCTTCTTTTTGCGACTCTTCATTCCGGAACGCATATTGGTGCTATCCATTTAGGTAGTAAAAAATAAGTCAGAATATGCCCTATAACACGATCGTGCAAAACCTGGTATATCGTCTCTATCTTTATCACAATATAGTGTATCAACATCTTTATTATTGACCTCGTTTATCTTGGAACATGGAATGGGAACATTTTTGTTAACGGCCACCTTTGCCTTAATTCCAGATGTTGTAAAATTATAACTAAACAGTCTATCATCGACACAAATGAAATTCTTGTTTAGACGTTTGTAGTTTACGTATGCGGCTCGTTCTCGTCTCATTTTTTCAGATATTGCAGGTACTATAATATTAAAAATAAGAATGAAATAACATAGGATTAAAAATAAAGTTATCATGACTTCTAGTGCTGATTTAACTAACTTAAAAGAATTACTTAGTCTGTACAAAAGTTTGAGATTTTCAGATTCTGTGGCTATAGAGAAGTATAATTCTTTGGTAGAATGGGGAACATCTACTTACTGGAAAATAGGCGTACAAAAGGTAACTAATGTCGAGACGTCCATATCTGATTATTATGATGAGGTAAAAAATAAACCGTTTAATATTGATCCGGGGTATTATATTTTCTTACCAGTATATTTTGGAAGCGTCTTTATTTATTCAAAGGGTAAAAATATGGTAGAACTTGGATCTGGAAACTCTTTTCAAATACCGGATGAGATTCGAAGTGCGTGTAACAAAGTATTAGATAGTGATAACGGAATAGACTTTCTGAGATTTGTTTTGTTAAACAATAGATGGATAATGGAAGACGCTATATCAAAATACCAGTCTCCAGTTAATATATTTAAACTAGCTAGTGAGTACGGATTAAACATACCCAACTATTTAGAAATTGAAATAGAGGAAGACACATTATTTGACGATGAGTTATACTCTATTATGGAACGCTCTTTCGATGATACATTTCCAAAAATATCTATATCGTATATTAAGTTGGGAGAACTTAAGCGGCAAGTTGTAGACTTTTTCAAATTCTCATTCATGTATATTGAGTCAATCAAGGTAGATCGTATAGGAGATAATATTTTTATTCCTAGCGTTATAACAAAATCAGGAAAAAAGATATTAGTAAAAGATGTAGACCATTTAATACGATCCAAGGTTAGAGAACATACATTTGTAAAAGTAAAAAAGAAAAACACATTTTCCATTTTATACGACTATGATGGGAACGGAACAGAAACTAGAGGAGAAGTAATAAAACGAATTATAGACACTATAGGACGAGACTATTATGTTAATGGAAAGTATTTCTCTAAGGTTGGTATTGCAGGCTTAAAGCAATTGACTAATAAATTAGATATTAATGAGTGTGCAACTGTCGATGAGTTAGTTGATGAGATTAATAAATCCGGAACTGTAAAACGAAAAATAAAAAACCAATCAGTATTTGATTTAAGCAGAGAATGTTTGGGATATCCAGAAGCGGATTTTATAACGTTAGTTAATAACATGCGGTTCAAAATAGAAAATTGTAAGGTTGTAAATTTCAATATTGAAAATACTAATTGTTTAAATAACCCGAGTATTGAAACTATATATGGAAACTTCAACCAGTTCGTCTCAATCTTTAATACCGTTACCGATGTCAAAAAAAGATTATTCGAGTGAAATAATATGCGCCTTTGATATAGGTGCAAAAAATCCTGCCAGAACTGTTTTAGAAGTCAAGGATAACTCCGTTAGGGTATTGGATATATCAAAATTAGACTGGAGTTCTGATTGGGAAAGGCGCATAGCTCAAGATTTGTCACAATATGAATACACTACAGTTCTTCTAGAACGTCAGCCTAGAAGGTCACCGTACGTCAAATTTATCTATTTTATTAAAGGCTTTTTATATCATACATCTGCTGCCAAAGTTATTTGCGTCTCACCTGTCATGTCTGGTAATTCATATAGAGATCGAAAAAAGAGATCTGTTGAAGCATTTCTTGATTGGATGGACACATTCGGATTGCGAGACTCCGTTCCGGATAGACGCAAATTAGACGATGTAGCGGATAGTTTCAATTTGGCTATGAGATACGTATTAGATAAATGGAATACTAATTATACACCTTATAATAGGTGTAAATATAGAAATTACATAAAAAAAATGTAATAACGTTAGTAACGCCATTATGGATAATCTATTTACCTTTCTACATGAAATAGAAGATAGATATGCCAGAACTATTTTTAACTTTCATCTAATAAGTTGTGATGAAATAGGAGATATATATGGTCTTATGAAAGAACGCATTTCCTCAGAGGATATGTTTGACAATATAGTATATAATAAAGATATACATCCTGCCATTAAGAAACTAGTTTATTGCGACATCCAACTTACTAAACATATTATTAATCAGAATACGTATCCGGTATTTAACGATTCTTCACAAGTGAAATGTTGTCATTATTTCGATATAAACTCAAATAATAGCAATATTAGCTCTCGTACAGTAGAGATATTTGAGAGTGAAAAGTCATCTCTTGTATCATATATTAAAACTACCAATAAGAAGAGAAAGGTCAATTACGGCGAAATAAAGAAAACTGTACATGGAGGCACTAATGCAAATTACTTTTCCGGTAAAAAGTCTGATGAGTATCTGAGCACTACAGTCAGGTCCAACATTAATCAACCTTGGATCAAAACCATTTCTAAGAGAATGAGAGTAGATATCATTAATCACTCTATAGTAACGCGTGGAAAAAGCTCTATATTACAAACTATAGAAATTATTTTTACTAATAGAACATGTGTGAAAATATTCAAGGATTCTACTATGCACATTATTCTATCCAAGGACAAGGATGAAAAGGGATGTATAAACATGATTGATAAATTATTCTATGTATATTATAATTTATTTCTGTTGTTCGAGGATATCATCCAAAACGATTACTTTAAAGAAGTAGCTAATGTTGTAAACCATGTACTCATGGCTACGGCATTAGATGAGAAATTATTCCTAATTAAGAAAATGGCTGAACACGATGTTTATGGAGTTAGCAATTTCAAAATAGGGATGTTTAACCTGACATTTATTAAGTTGTTGGATCATACCGTTTTCCCCTCTCTGTTAGATGAGGATAGCAAAATAAAGTTTTTTAAGGGGAAAAAGCTCAATATTGTAGCATTACGATCTCTGGAGGATTGTACAAATTACGTGACTAAATCCGAGAATATGATAGAAATGATGAAGGAAAGATCGACTATTTTAAATAGCATAGATATAGAAACGGAATCGGTAGATCGTCTAAAAGAATTGCTTCTAAAATGAAAAAAAACACTGATTCAGAAATGGATCAACGACTCGGGTATAAGTTTTTGGTGCCTGATCCTAAAGCCGGAGTTTTTTATAGACCGTTACATTTCCAATATGTATCGTATTCTAATTTTATATTGCATCGATTGCATGAAATCTTGACCGTCAAGCGGCCACTCTTATCGTTTAAGAATAATACAGAACGAATTATGATAGAAATTAGCAATGTTAAAGTGACTCCTCCAGATTACTCACCTATAATTGCGAGTATTAAAGGTAAGAGTTATGACGCATTAGCCACGTTCACTGTAAATATCTTTAAAGAGGTAATGACCAAAGAGGGTATATCCATCACTAAAATAAGTAGTTATGAGGGAAAAGATTCTCATTTGATAAAAATTCCGCTACTAATAGGATATGGGAATAAAAATCCACTTGATACAGCCAAGTATCTTGTTCCTAATGTCATAGGTGGAGTCTTTATCAATAAACAATCTGTCGAAAAAGTAGGAATTAATCTAGTAGAAAAGATTACAACATGGCCAAAATTTAGGGTTGTTAAGCCAAACTCATTCACTTTCTCGTTTTCCTCCGTATCCCCTCCTAATGTATTACCGACAAGATATCGCCATTACAAGATATCTCTGGATATATCACAATTGGAAGCGTCGAATATATCATCGACAAAGACATTTATAACGGTCAATATTGTTTTGCTGTCTCAATATTTATCTAGAGTGAGTCTAGAATTCATTAGACGTAGTTTATCATACGATATGCCTCCAGAAGTTGTCTATCTAGTAAACGCGATAATAGATAGTGCTAAACGACTTACCGAATCTATTACTGACTTTAATATTGATACATACATTAATGACCTGGTGGAAGCTGAACACATTAAACAAAAATCTCAGTTAACGATTAACGAGTTTAAATATGAAATGCTGCATAACTTTTTACCTCATATGAACTATACACCCGATCAACTAAAGGGATTTTATATGATATCTTTACTAAGAAAGTTTCTCTACTGTATCTACCACACTTCTAGATATCCAGATAGAGATTCGATGGTTTGTCATCGCATCCTAACGTACGGCAAATATTTTGAGACGTTAGCACATGATGAATTAGAGAATTACATAGGTAACATCCGAAACGATATCATGAACAATCACAAGAACAGAGGCACTTACGCAGTAAACATTCATGTACTAACAACTCCTGGACTTAATCATGCATTTTCTAGTCTATTGAGTGGAAAGTTCAAAAAGTCAGACGGTAGTTATCGAACACATCCTCACTATTCATGGATGCAGAATATTTCTATTCCTAGAAGTGTTGGATTTTATCCGGATCAAGTAAAGATTTCAAAGATGTTTTCTGTCAGAAAATACCATCCAAGCCAATATCTTTACTTTTGTTCATCAGACGTTCCGGAAAGAGGTCCTCAGGTAGGTTTAGTATCTCAATTGTCTGTCTTGAGTTCCATTACAAATATACTAACGTCTGAGTATTTGGATTTGGAAAAGAAAATTTGTGAGTATATCAGATCATATTATAAAGATGATATAAGTTACTTTGAAACAGGATTTCCAATCACTATAGAAAATGCTCTAGTCGCATCTCTTAATCCAAATATGATATGTGATTTTGTAACTGACTTTAGACGTAGAAAACGGATGGGATTCTTCGGTAACTTGGAGGTAGGTATTACTTTAGTTAGGGATCACATGAATGAAATTCGCATTAATATTGGAGCAGGAAGATTAGTCAGACCATTCTTGGTTGTGGATAACGGAGAGCTCATGATGGATGTGTGTCCGGAGTTAGAAAGCAGATTAGACGACATGACATTCTCTGACATTCAGAAAGAGTTTCCACATGTCATCGAAATGGTAGATATAGAACAATTTACTTTTAGTAACGTATGTGAATCGGTTCAAAAATTTAGAATGATGTCAAAGGATGAAAGAAAGCAATACGATTTATGTGACTTTCCTGCCGAATTTAGAGATGGATATGTAGCATCTTCACTAGTGGGAATCAATCACAATTCTGGACCCAGAGCTATTCTTGGATGTGCTCAAGCTAAACAAGCTATCTCTTGTCTGAGTTCGGATATACGAAATAAAATAGACAATGGAATTCATTTGATGTATCCAGAGAGGCCAATTGTGATTAGTAAGGCTTTAGAAACTTCAAAGATTGCGGCTAATTGCTTCGGACAACATGTTACTATAGCATTAATGTCGTACAAAGGTATCAATCAAGAGGATGGAATTATCATCAAAAAACAATTTATTCAGAGAGGCGGTCTCGATATTGTTACAGCCAAGAAACATCAAGTAGAAATTCCATTGGAAAACTTTAATAACAAAGAAAGAGATAGGTCTAACGCCTATTCGAAATTAGAAAGTAATGGATTAGTTAGACTGAATGCTTTCTTGGAATCCGGAGACGCTATGGCAAGAAATATCTCATCAAGAACTCTTGAAGATGATTTTGCTAGAGATAATCAGATTAGCTTTGATGTTTCCGAGAAATATACAGATATGTACAAATCTCGCGTTGAACGAGTACAAGTAGAACTTACTGACAAAGTTAAGGTGCGAGTATTAACCATGAAAGAAAGAAGACCCATTCTAGGAGACAAATTTACTACTAGAACGAGTCAAAAGGGAACAGTCGCGTATATCGCAGATGAAACGGAACTTCCGTACGACGAAAATGGTATCACACCAGATGTCATTATTAATTCTACATCCATCTTCTCTAGAAAAACTATATCTATGTTGATAGAAGTTATTTTAACAGCCGCATATTCTACTAAGCCGTACAACAATAAGGGAGAAAACCGACCTGTCTGTTTTCCTAGTAGTAACGAAACATCTATCGATGCATATATGCAATTCGCTAAACAATGTTATGAGTATTCAAATCCGAAATTGTCCGAGGAAGAATTATCGGATAAAATCTTTTGTGAAAAGATTCTCTATGATCCTGAAACGGATAAGCCTTATGAATCCAAAGTATTTTTTGGACCAATTTATTACTTGCGTCTGAGACATTTAACTCAGGACAAGGCAACCGTTAGATGTAGAGGTAAAAAGACGAAGCTCATTAGACAAGCGAATGAGGGACGAAAACGTGGAGGAGGTATCAAGTTTGGAGAAATGGAGAGAGACTGTTTAATAGCACATGGTGCAGCCAATACTATTACAGAAGTTTTAAAAGACTCAGAAGAGGATTATCAAGATGTGTATATTTGTGAAAATTGTGGAGACATAGCAGCACAAATCAAAAGTATTAATACATGTCTTAGATGTTCAAAACTTAATCTCTCTCCTCTCTTAACAAAAATTGATACCACGCACGTATCTAAAGTATTTCTTACTCAAATGAACGCCAGAGGCGTAAAAGTTAAATTAGATTTCGAACGAAGGCCTCCTTCGTTTTATAAACCATTAGATAAAGTTGATCTTAAACCGTCTTTTCTGGTATAATATTGTTTAGTAGATACTCATCAAGATAAGCTAATTCACTAAACATATTATCGGATTCGGTATTGTTACTCGAGAATAGAGTTCGTTATGCTCCTGATATTCGGAAATCTGTGGAGTTTCAGGTTTTGGTGGAAGTGTAACTGCTACTTGGTGGGATACTGAAGGATATTTCAGAGAGTTGTGGATGTTCGGGTTCGACATCCACCGATGGTGTCACGCCACTAATCGGTTCGGTAACGTCTGTGGATGGAGGTGCTACTTCTACAGAACCTGTAGCCTCAGTTGTCAACGGAGATACATATTCAATGCGCGGAAATGTATAATTTGGTAATGGTTTCTCATGTGGATCTTAAGAAGAAGAGGTAAGATATCTACGAAAGATACCGATCACGTTTCTAGTTCTCTTTTGTAGAACTTTAACTTTTTCTTTCTCAGCATCTAGTTGATATTCCGACCTCTTCACGTTTCGCATGGGTTACCTCCGCAGTTTTTACAAGCGATTTCACGTTCCAGATCACGTTCAGCCTTCATACGTCTCTCCCTCTCTCTATCGAGTTTATCAGAGCAGTCTTTCTGAAGGCGATCGAACTCCATAAATTTCTCCAACGCTTTGATTGTTTCCATAGATTTCCGAAGTTTAGCTTCTAGGACGGCGATTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCGAATTCACGGGGTACAACCGTTTCCATTACCACCATCTCTATGTTTCTTTTCTAGATCGGCAATCTTTCTCAACATTTCATCCCCATACCTTTTCATTCCTCGAGTCTATTGTCGTCGAAATATCGTTCCAGCTCCTTTTCGACCTCAATAACTTTAGCACGTTGTTTCATCAAGCTCTCTCTTGTAGTACTATCATTTTTATCTGATTCCCTGACACGTTTAAGATCTTCATGTAATTGAGTCAGCTCTTGACGCAATCTCTTAACTAACTTCCTCTCTTGCTTCTTCGTCATAGTACTTACAATCACTATGGGATCCATTGTTACCACGTCTGTACTCGACGAGCTCACGTTTAAGAGATTCAATTTCCAGTTTGTATCGGTCCATGTCTCCATTGCTACACCACCATTAGATTTACAGGCTGCTAGTTGTCGTTCGAGATCAGAAATACGTGTTTTCTTGGAATGGATTTCGTCGATGTACTTGTCATGATTGGCATCGAAACACTTATTAAGTTCTTTTTTTCAATTCTACGATTTTATTTCTTTCGCGAGTCAATTCCCTCCTGTAGTAACTATCAGTTTTGTCAGATTCACGCTCTCTACGTAGACTTTCTTGTAAGTTACTAATTTGTTCCCTGGCATTACCGAGTTCAGTTTTATATGCCGAATAGAGTTCTGATTCATCCTTTGAGAAGATCTCTAGCGATCGTTCAAGATCCCTGATTCTAGTCTTTAGCCTATTTACCTCCTCAGAAGATGCTCCGTTACCGTTTTTACAATCGTTAAGATGTCTATCAAGATCCATGATTCTATCTCTTTTCCATATCAGCATTGATTTCATTATTACGTTCGCAGTCGTTCAACTGTATTTCAAGATCTGAGATTCTAGATTGTAATCTCTGTAGCATTTCCACGGCATTCACTCAGTTGTCTTTCAAGATCTGAGATTCTAGATTGGAGTCTGCTAATCTCTGTAAGATTTCCTCCTCCGCTCTCGATGCAGTCGGTCAACTTATTCTCTAGTTCTCTAATACGCGAACGCAGTGCATCAACTTCTTGTGTGTCTTCTTGATTGCGTGTGCATTCATCGAGTCTAGATTCGAGATCTCTAACGTGACGTCGTTCTTCCTCAAGTTCTCTGTGTACTACAGAAAGCGTGTCCCTATCTTGTTGATATTTAGCAATTTCTGATTCTAGAGTACTGATTCTACTCACGTATGTACTAATAGTTGTCTTAGCCTTATCAAGATCCTCCTTGTATTTGTCACATTCCTTGATATCCATACGAAGTCTGGACAGTTCCCATTCGACATTACGACGTTTATCGATTTCAGCTCGGAGATCGTCGTCGCGTTGTTTTAGCCACATACGACTAAGTTCAAGTTCTCGTTGACAAGATCCATCTACTTTTCCATCCCTAATAGTATCCAGTTCCTTTTCTAGTTCTGACCGCATTTCTCGTTCCATATCAAGAGATTCTCTCAATTCTCGTATAGTCTTCTTATCAATTTCTGATGAATCTGAACCATCATCTGTCCCATTTTGTTGCATATCCCTGAGTTCTTTGATCTCTGTTGTAAGTCTGTCGATTCTTTCGGTTTTATAAACAGAATCCCTTTCCAAAGTCCTAATCTTACTGAGTTTATCATTAAGTTCTTCATTCAATTCAGTGAGTTTTCTCTTGGCTTCTTCCAAGTCTGTTTTAAACTCTCCATCATTTCCGCATTCTTCCTCGCATTTATCTAACCATTCAATTAGTTTATTAATAACTAGTTGGTAATCAGCGATTCCTATAGCCGTTCTTGTATTTGTGGGAACATAATTAGGATCTTCTAATGGATTGTATGGCTTGATAGCATCATCTTTATCATTATTAGGTGGGGGATGGACAACCTTAATTGGTTGGTCCTCCTTATCTCCTCCAGTAGCATGTGGTTCTTCAATACCAGTATTAGTAATAGGCTTAGACAAATGCTTGTCGTACGCGGGCACTTCCTCATCCATCAAGTATTTATAATCGGGTTCTGTTTCAGAATATTCTTTTCTAAGAGACGCGACTTCAGGAGTTAGTAGAAGAACTCTGTTTCTGTATCTATCAACGCTGGAATCGATACTCAAGTTAAGGATAGCGAATACCTCATCGTCATCATCCGTATCTTCTGAAACGCCATCATATGACATTTCATGAAGTCTAACGTATTGATAAACAGAATCAGATTTAGTATTAAACAGATCCTTGACCTTTTTAGTAAATGCATATGTATATTTTAGATCTCCAGATTTCATAATATGATCGCATGCCTTAAATGTCAATGCTTCCATGATATAGTCTGGAACACTAATGGGTGACGAAAAAGATACAGCACCATATGCTACGTTGATAAATAGATCTGAACCACTAAGTAGATAATGATTAATGTTAAGGAAGAGGAAATATTCAGTATATAGATATGCCTTAGCATCATATCTTGTACTAAACACGCTAAACAGTTTATTGATGTGATCAATTTCCAACAGAACAATTAGAGCGGCAGGAATACCAACAAACATATTACCACATCCGTATTTTCTATGAATATCACATATCATATTAAAAAATCTTGATAGAAGAGCGAATATCTCGTCTGACTTAATGAGATGTAGTTCAGCAGCATAAGTCATAACTGTAAATAGAACATACTTTCCTGTAGTGTTGATTCTAGACTCCACATCAACACCATTATTAAAAATAGTTTTATATACATCTTTAATCTGCTCTCCGTTAATCGTCGAACGTTCTAGTATACGGAAACACTTTGATTTCTTATCTGTAGTTAATGACTTAGTGATATCACGAAGAATATTACGAATTACATTTCTTGTTTTTCTTGAGAGACCTGATTCAGAACTCAACTCATCGTTCCATAGTTTTTCTACCTCAGTGGCGAAATCTTTGGAGTGTTTGGTACATTTTTTAATAAGGTTCGTGACCTCCATTTATTATAAAAAATTTTTATTCAAAACTTAACTACAATCGGGTAATTATAAGATCGTAGATCTCCCATGTGGTGGAATACTACCATCTATCGCATGTTGATGGACAGTAGGTAATGGCCATGGGAACAGTAATGTTTGCATATTTATCTTTCTTGCTAGTATTACTGTATATTGTCCCAATGTTTCAATGTGATGTTCTAACCTATCAACTGCCACTGTATCACAACAATAATGTCCGATGGAATTAAGATTATGATCCAATGTGTTTAATATATGATTATCAAGTCTTATACGATCCGCGTCTTTTTTGACAGGATCAGGCTCTTCTACAGGAAGAAGTTTCGGCCTCTTATGATAGTCATGTCTGGGAAATGGTGGTCTAGGATGAGGATCAGGTATCGGAGTAGGTTTTGGATTATAATCATCATCATCATCATCATCATCATCATCATCATCATCATCTATGATATCATCATCTTCGATATTTATTTTGCTATCTTGATAATGTCCTATATCAGTTGCATTTTCAGCACTCGACTGAATATTAGTACATTCATTGTCTATTATTAACGTATTTCTAAACCCAAAATGTATATGTTGAACATCACTACTATAGTTGATGAGTCTTATAGCATGAATTCGCTTATCGTTATCGGGTTTATCTTCTGTCACCTTAACAATTCCTTTTTTATTAAACTCTGCATAATCATAACCATTTCTATTGTTTGTTCTAATATAAACGAGTATAGCATCATTGCTAAATTTTTCAATAGTATCAAAAACAGAATATCCTAAACCATATAATATATATTCAGGAACACTCAAACTAAATGTCCAGGATTCTCCTAAATACGTAAACTTTAATAGTGCTAAATCATTCAAAAATCTACCGCTTATAGATAGATAGTACATGAATGCGTATAGTAGTCTACCTATCTCTTTATTATGAAAACCGACATTACGATCATATATTTCGTGATATACATGTGACCCGTTTACGTTAAACCATAAATACATGGGTGATCCTATAAACATGAATTTATTTCTAATTCTCAGAGCCATAGTTAATTGACCGTGTAATATTTGTTTACATGCATACTTGATACGATCATTAATAAGATTTTTATCATTGCTCGTTATTTCAGAATCGTATATATAAGGAGTACCATCATGATTCTTACCAGATATTATACAAAATACTATATATAAAATATATTGACCCACGTTAGTAATCATGTAAATGTTTAATGTTTTAAATTTTGTATTTAATGATCCATCATCATATGCTAGCATGGTCTTGTGATATTCATTCTTTAAAATATAATATTGTGTTAGCCATTGCATTGGAGCTCCTAATGGAGATTTTCTATTCTCGTCCATTTTAGGATATGCTTTCATAAAGTCCCTAATAACTTCGTGAATAATGTTTCTATGTTTTCTACTGATGCATGTATTTGCTTCGATTTTTTTATCCCATGTTTCATCTATCATAGATTTAAACGCAGTAATGCTCGCAACATTAACATCTTGAACCATTGGTACAATTCCGTTCCATAAATTTATAATGTTCGCCATTTATATAACTCATTTTTTGAATATACTTTTAATTGAACAAAAGAGTTAAGTTACTCATATGGATGCCGTCCAGTCTGTACATCAATCTTTTTAGCCAGAGATATCATAGCCGCTCTTAGAGTTTCAGCGTGATTTTCCAACCTAAATAGAACTTCATCGTTGCGTTTACAACACTTTTCTATTTGTTCAAACTTTGTTGTTATATTAGTAATCTTTTTTTCCAAATTAGTTAGCCGTTGTTTGAGAGTTTCCTCATTATCGTCTCCATAGGCTTTAACAATTGCTTCGCGTTTAGTCTCTGGATTTTTAGCAGCCTTTGTAGAGAAAAATTCAGTTGCTGGAATTGCAAGATCGTCATCTCCGGGGAAAAGAGTTCCGTCCATTTAAAGTACAGATTTTAGAAACTGACACTCTGTGTTATTTATATTTGGCGCAATACATGGATTATAAATATCGATGTTAATAACATCAGAAAATGTAAAGTCTATACATTGTCGCATCGTGTTAAATTTTCTAATGGATCTAGTATTATTGGGTCCAACTTCTGCCTGAAATCCAAATATGGAAGCGGATACAAAACCGTTTCCTGGATAAACCACACATCTCCACTTTTGCTTTACATCAGAAATTGTGTCATTGACATCTTGAACTCTCCTATCTAATGCCGGTGTTCCACCTATAGATTTTGAATACTCGAATGCTGCATGAGTAGCATTGAATTCCTTAATATTGCCATAATTTTCATATATTGAGTAACTCTGGATAAAAAGTAAACACACCGCAGCCGTCGCTACTACAATAAAAAAAATTGATAGAGAGTTCATTTATAATCTATTAGAAGCTGATAAAATTTTTTTACACGCGTCAGACAATGCTTTAATAAATAGTTCAACATCTACTTTTGTCATATCGAACCGATGGTATGATTCTAACCTAGAATTACATCCGAAAAAGTTGACTATGTTCATAGTCATTAAGTCATTAACGAACAACATTCCAGACTCTGGATTATAAGACGATACTGTTTCGTCACAATCACCCACCTTAATCATGTGATTATGAATATTGGCTATTAGAGTACCTTCTAAGAAATCTATAATATCTTTGAAACACGATTTAAAATCAAACCACGAATATACTTCTACGAAGAAAGTTAGTTTACCCATAGGAGAGATAACTATAAATGGAGATCTAGATACAAAATCCGGATCTATGATAGTTTTAACATTATTATATTCTCTATTAAATACCTCCACATCTAAAAATGTTAATTTTGAAACTATGTCTTCGTTTATTACCGTACCTGAACTAAACGCTATAAGCTCTATTGTTTGAGAACTCTTTAAACGATATTCTTGAAATACATGTAACAAAGTTTCCTTTAACTCGGTCGGTTTATCTACCATAGTTACAGAATTTGTATCCTTATCTATAATATAATAATCAAAATCGTATAAAGTTATATAATTATCGTGTTCAGATTGTGATCTTTTCAAATAGACTAAAAACCCCATTTCTCTAGTAAGTATCTTATGTATATGTTTGTAAAATATCTTCATGGTGGGAATATGCTCTACAGCAGTTAGCCATTCCTCATTGACAGCTGTAGATGTATTATACAAAACTACTCCAATGTTTAACAAGGGCCATTTTACGAGATTATTAAATCCTTGTTTGATAAATGTAGCCAATGCGGGTTCGAGTTCAACGACGATTGAATTCTCTTCCCGTGGATGCTGCATGATGAACGACGGGATGTTGTTGTTCTATTGATTTGGAATTCTTTTTCGACTTTTTGTTTATATTAAATATTTTAAAATTTATGGCTGATAGTAATTCATGTACTACGGATAATGTAGACGTGTATTGCATATCGATATCTTTATTATTAGATAAATTTATCAATAAATGTGAGAAGTTTGCCTCGTTAAGGTCTTCCATTTAAATATTATATAAATATTTGTGTTTGTATTTTATTCGTCTTTTATGGGATAGTTTTTAACTAGTAAAGCTGTAATTACATACTTTGTCCGTAAAACATAAATATAAATACCCGCTTTTATCAAACGTTCCAAAAAGTCGGCAGCTGACATTTTTAACATGACATCTATTTTAAATACACTTAGGTTTTTAGAAAAAACATCATTTTATAATTGTAACGATTCAATAACTAAAGAAAAGATTAAGATTAAACATAAGGGAATGTTATTTGTATTTTATAAGCCAAAGCATTCTACCGTTGTTAAATACTTGTCTGGAGGAGGTATATATCATGATGATTTGGTTGTATTGGGGAAGGTAACAATTAATGATCTAAAGATGATGCTATTTTACATGGATTTATCATATCATGGAGTGACAAGTAGTGGAGCAATTTACAAATTGGGATCGTCTATCGATAGACTTTCTCTAAATAGGACTATTGTTACAAAAGTTAATAACAATTATAACAATTATAACAATTATAACAATTATAATTGTTATAATAATTATAATTGTTATAATTATGATGATACATTTTTTGACGATGATGATTGATCACTATTACACAATTTTGTTTTTGTACTTTCTAATATAGTGTTTAGGTTCTTTTTCATATGAGAATATTGACTTACTAAAATATCTATGTTTAACTTTTGTTCTATAACGTCCTTATCGGCGGTATCGGTACATATACGTAATTCACCTTCACAAAATACGGAGTCTTCGATAATAATAGCCAATCGATTATTGGATCTAGCTGTCTGTATCATATTCAACATGTTTAATATATCCTTTCGTTTCCCCTTTACAGGCATCGATCGTAGCATATTTTCCGCGTCTGAGATGGAAATGTTAAAACTGCAAAAATGCGTAATGTTAGCCCGTCCTAATATTGGTACGTGTCTATAAGTTTGGCATAGTAGAATAATAGACGTGTTTAAATGCCTTCCAAAGTTTAAGAATTCTATTAGAGTATTACATTTTGATAGTTTATCACCTACATCATCAAAAATAAGTAAAAAGTGTGCTGATTTTTTATGATTTTGTGCGACAGCAATACATTTTTCTATGTTACTTTTAGTTCGTATCAGATTATATTCTAGAGCTTCCTGACTACTAACGAAATTAATATGATTTGGCCAAATGTATCCATCATAATCTGGGTTATAAACGGGTGTAAACAAGAATATATGTTTATATTTTTTAACTAGTGTAGAAAACAGAGATAGTAAATAGATAGTTTTTCCAGATCCAGATCCTCCTGTTAAAACCATTCTAAACGGCATTTTTAATAAATTTTCTCTTGAAAATTGTTTTTCTTGAAAACAATTCATAATTATATTTACAGTTACTAAATTAATTTGATAATAAATCAAAATATGGAAAACTAAGGTCGTTAGTAGGGAGGAGAACAACGAAGGCATATCGTGATATAAATAACATTTATTATCATGATGACACCAGAAAACGACGAAGAGCAGACATCTGTGTTCTCCGCTACTGTTTACGGAGACAAAATTCAGGGAAAGAATAAACGCAAACGCGTGATTGGTCTATGTATTAGAATATCTATGGTTATTTCACTACTATCTATGATTACCATGTCCGCGTTTCTCATAGTGCGCCTAAATCAATGCATGTCTGCTAACAAGGCTGCTATTACTGACTCCGCTGTTGCCGTTGCTGCGGCATCATCTACTCATAGAAAGGTTGTGTCTAGCACTACACAATATGATCACAAAGAAAGCTGTAATGGTTTATATTACCAGGGTTCTTGTTATATATTACATTCAGACTATAAGTCATTCGAGGATGCTAAAGCAAACTGCGCTGCGGAATCATCAACACTACCCAATAAATCCGATGTCTTGACTACCTGGCTCATTGATTATGTTGAGGATACATGGGGATCTGATGGTAATCCAATTACAAAAACTACATCCGATTATCAAGATTCTGATGTATCACAAGAAGTTAGAAAGTATTTTTGTACATAAATAAATGAAATCGCTTAATAGACAAACTGTAAGTAGGTTTAGGAAGTTGTCGGTGCCGGCCGCTATAATGATGTTACTCTCAACCATTATTAGCGGCATAGGAACATTTCTGCATTACAGAGAAGAACTGATGCCTAGTGCTTGCGCCAATGGATGGATACAATACGATAAACATTGTTATCTGGATACCAACATTAAAATGTCTACGGATAATGCAGTTTATCAGTGTCGCAAATTACGAGCTAGATTGCCTAGACCTGATACTAGACATCTGAGAGTATTGTTTAGTATTTTTTATAAAGATTATTGGGTAAGTTTAAAAAAGACCAATGATAAATGGTTAGATATTAATAATGATAAAGATATAGATATTAGTAAATTAACAAATTTTAAGCAACTAAACAGCACGACGGATTCTGAGGCGTGTTATATATACAAGTCTGGAAAACTGGTTAAAACAGTATGTAAAAGTACTCAATCTGTACTATGCGTTAAAAGATTCTACAAGTGACAACAAAAAATGAATTAATAGTAAGTCGTTAACGTACGCCGCCATGGACGCCGCGTTTGTTATTACTCCAATGGGTGTGTTGACTATAACAGATACATTGTATGATGATCTCGATATCTCAATCATGGACTTTATAGGACCATACATTATAGGTAACATAAAAATTGTCCAAATAGATGTACGGGATATAAAATATTCCGACATGCAAAAATGCTACTTTAGCTATAAGGGTAAAATAGTTCCTCAGGATTCTAATGATTTGGCTAGATTCAACATTTATAGTATTTGTACAGCATACAGATCAAAAAATACCATCATCATAGCATGCGACTATGATATCATGTTAGATATAGAAGGTAAACATCAACCATTTTATCTATTCCCATCTATTGATGTTTTTAACGCTACAATCATAGAAGCGTATAATCTGTATACAGCTGGAGATTATCATCTGATCATCAATCCTTCAGATAATCTGAAAATGAAATTGTCGTTTAATTCTTCATTTTGTATATCAGACGGCAATGGATGGATTATAATTGATGGGAAATGTAATAGTAATTTTTTATCATAAAAGTTGTAAAGTAAATAATAAAACAATAAATATTGAACTAGTAGTATGTTGTATATTGAGCAATCAGAGATGATGCTGGTACCTCTTATCACGGTGACCGTAGTTGCGGGAACAATATTAGTATGTTATATATTATATATTTGTAGGAAAAAGATACGTACTGTCTATAATGACAATAAAATTATCATGACAAAATTAAAAAAGATAAAGAGTCCTAATTCCAGCAAATCTAGTAAATCAACTGATAGCGAATCAGACTGGGAGGATCACTGTAGTGCTATGGAACAAAACAATGACGTAGATAATATTTCTAGAAATGAGATATTGAACGATGATAGCTTCGCTGGTAGTTTAATATGGGATAACGAATCCAATATCATGGCGCCTAGCACAGAACACATTTACGATAGTGTTGCTGGAAGCACGCTGCTAATAAATAATGATCGTAATGAACAGACTATTTATCAGAATACTACAGTAGTAATTAATGATACAGAGACTGTTGAAATACTTAATGAAGATACCAAACAGATTCCTAGCTATTCTTCCAATCCTTTCGTAAATTATAATAAAACCAGTATTTGTAGCAAGTCAAATCCGTTCATTGCAGAACTCAACAATAAATTTAGTGATAATAATCCGTTTAGGAGAGCACATAGTGACGATTATCTTAATAAGCAACAAGATCATGAATACGATGATATAGAATCATCGGTTGTATCATTGGTCTGATTAGTTTCCTTTTTATAAAATTGAAGTAATATTTAGTATTAATTACCGCCGATGCATTATACAAATATGGAGATATTCCCTGTATTCGGCATTTCTAAAATTAGCAATTTTATTGCTAATAATGACTGTAGATATTATATAGATGTAGAGCATCAAAAAATTATATCTGATGAGATCAATAGACAGATGGATGAAACGGTACTTCTTACCAACATCTTAAGCGTAGAAGTTGTAAATGACAATGAGATGTACCATCTTATTCCCCATAGACTATCGACTATTATACTCTGTATTAGTTCTGTTGGAGGATGTGTTATCTCTATAGATAATGACGTCAATGACAAAAATATTCTAACATTTCCCATTGATCATGCTGTAATCATATCCCCACTGAGTAAATGTGTCGTAGTTAGCAAGGGCCCTACAACCATACTGGTTGTTAAAGCGGATATACCCAGCAAACGATTGGTAACATCGTTTACAAACGACATACTGTATGTAAACAATCTATCACTGATTAATTATTTACCGTCGTCTGTATTCATTATTAGACGAGTCACCGACTATTTGGATAGACACATATGTGATCAGATATTTGCTAATAATAAGTGGTATTCCATTATAACTATCGACGATAAGCAATATCCTATTCCATCAAATTGTATAGGTATGTCTTCTGCCAAGTACATAAATTCGAGCATCGAGCAAGATATTTTGATCCATGTTTGTAACCTCGAGCATCCATTCGACTCAGTCTACAAAAAAATGCAGTCGTACAATTCTCTACCTATCAAGGAACAAATATTGTATGGTAGAATTGATAATATAAATATGAGCATTAGTATTTCGGTGGATTAATAGATTTCTCTAGTATGGGATCATTAATCATCTCTAAATACATCATAAAAAAGCTATTATCAAATACTGTACTGAATGGATTCATTCTTTTCTCTTTTTATGAAACTCTGTTGTATATCTACGGATAAAACTAGAAGCAAAAAATCTGATAGGAAGAATAATGATTATATGGAGGAACACGATTATTATAAAATAACAATAGTTCCTGGTTCCTCTTCCACGTCTACTAGCTCGTGGTATTATACACATGCCTAGTAATAGTCTCTTTGCGTTGACGGAAAGCAGACTAGAAATAACAGGCCAAAATGTTCAGACACCATAATAGTTCCCAACCCAGATAATAACAGAGTTCCATCAACACATTCCTTTAAACTCAATCCCAAACCCAAAACCGTTAAAATGTATCCAGCCAATTGATAGTAGATAATGAGGTGTACAGCACATGATAATTTACACAGTAACCAAAATGAAAACACTTTAGTAATTATAAGAAATATAGACGGTAATGTCATCATCAACAATCCAATAATATGCCTGAGAGTAAACATTGACGGATAAAACAAAAATGCCCCGCATAACTCTATCATGGCAATAACGCAACCAAACACTTGTAAAATTCCTAAATTAGTAGAAAATACAACTGATATCGATGTATAAGCGATTTCGAGGAATAATAAGAACAAAGTAATTCCCGTAAAGATAAACATCAACATTGTTTGGTAATCATTAAACCAATTAGTATGACGTTGAATTAATTTCACAGTATATTTTATTCCAGTATTATCCCCGCATGTATACGTACCTGGTAAGATATCTTTATATTCCATAATCAATGAGACATCACTATCCGATAACGAATGAAGTCTAGCACTAGTATGCCATTTACTTAATATGGTCGTCTTGGAAGTTTTATTATAAGTTAAAATATCATGATTGTCCAATTTCCATCTAATATACTTTGTCGGATTATCTATAATACACGGAATAATGATGGTATCATTACATGCTGTATATTCTATAGTCTTTGTAGATGTTATAACCACAAAAGTACAGAGGTATATCAACAATATTCTAACTCTTAACATTTTTATTTATTTAAAATGATACCTTTGTTATTTATTTTATTCTTATTTTGCTAACGGTATCGAATGGCATAAGTTTGAAACGAGTGAAGAAATAATTTCTACTTACTTAATAGATTATGTGGTAACGGGTGTTATTAATGGGGATGTATATACATTTTCAAATAATGAACTAAACAAAACTGGGTTAACTAATAACAATAATTATATCACAACATCTATAAAAGTAGAGGATAAGGATACATTAGTAGTATGCGGAACCAATAACGGAAATCCCAAATGTTGGAAAATAGACGGTTCATACTACCCAAAACATATAGGTAGAGGATACGATCATCAAAATAGCAAAGTAACGATAATCAGTCACAATGAATGTGTACTATCCGACATAAACATATAAAAAGAAGGAATTAAACGATGGAGAAGATTTGACGGACCATGTGGTTATGATTAAACGAGTTAAGTTTTTTAAGAAGCCTTAGAAGAGAGGCTATTGGGTATGAGAATCCGAAATATTAAACCAGACAACCCCATATAATTTTATAGCTAAGAATGCCGCGAAGAATGGAACTAATAAAAACGGAAATATTTGTAGCACAACGAATAACTCCCAAACTGCATTCATGTTACACTATATAACACTACTTCGGTTAGATGTTTTAGAAAAAATAAATATCACCGTACCGTTTTGTTGTATAAAAATAACAATTAACAATTATCAATTTTTTTCTTTAATATTTTACGTGGTTGACCATTCTTGGTGGTAAAATAATCTCTTAGTGTTGGAATGGAATGCTGTTTAATGTTTCCACACTCATCGTATATTTTGACGTATGCAGTCACATCGTTTACGCAATAGTCAGACTGTAGTTCTATCATGCTTCCTACGTTAGAAGGAGGAACAGTTTTAAAGTCTCTTGGTTTTAATCTATTGTCATTAGTTTTCATGAAATCCTTTGTTTTATCCACTTCACATTTTAAATAAATGTCCACTATACATTCTTCTGTTAATTTTACTAGATCATCATGAGTCATAGAATTCATAGGTTCCGTAGTCCATGGATCCAAACTAGCAAACTTCGCGTATACGGTATCGCGATTAGTGTATACACCAACTGTATGAAAATTAAGAAAACAGTTTAATAAATCTACAGAAATATTTAATCCTCCGTTTGATACAGATGCGCCATATTTATGGATTTCGGATTCACACGTTGTTTGTCTAAGGGGTTCGTCTAGTGTTGCTTCTACATAGACTTCGATTCCCATATATTCTTTATTGCCAGAATCACATACCGATTTATCATACGCTGGTTCACTTGTTTGAAAACTAAATGGTAGTAGATACATCAAAATAATAAATAATAAGTACATTCTGCAATATTGTTATCGTAATTGGAAAATTGGTATTCAAGTGAGCTGGATTATGTGAGTATTGGATTGTATATTTTATTTTATATTTTATATTTTATATTTTATTTTATATTTTATATTTTATTTTATATTTTGTAGTAAGAATAGAATGCTAATGTCAAGTTTATTCGAATAGATGTCTTATTAAAAAACATATATAATAAATAACAATGGCTGAATGGCATAAAATTATCGAGGATATCTCAAAAAATAATAAGTTCGAGGATGCCGCCATCGTTGATTACAAGACTACAAAGAATGTTCTAGCGGCTATTCCTAACAGAACATTTGCAAAGATTAATCCGGGTGAAGTTATTCCCCTCATCACTAATCATAATATTCTAAAACCTCTTATTGGTCAGAAATTTTGTATTGTATATACTAACTCTCTAATGGATGAGAACACGTATGCTATGGAGTTGCTTACTGGGTACGCCCCTGTATCTCCGATCGTTATAGCGAGAACTCATACCGCACTTATATTTTTGATGGGTAAGCCAACAACATCCAGACGTGATGTGTATAGAACATGTAGAGATCACGCTACCCGTGTACGTGCAACTGGTAATTAAAATAAAAAGTAATATTCATATGTAGTGTCAATTTTAAATGATGATGAAATGGATAATATCCATATTGACGATGTCAATAATGCCGGTATTGACATACAGCTCATCGATTTTTAGATTTCATTCAGAGGATATTGAATTATGTTATGGGAATTTGTATTTTGATAGGATCTATAATAATGTAGTAAATATAAAATATATTCCTGAGCATATTCCATATAGATATAATTTTATTAATCGTACGTTCTCCGTAGATGAACTAGATGATAATGTCTTTTTTACACATGGTTATTTTTTAAAACACAAATATGGTTGTTCACTTAATCCTAGTTTGATTGTCTCATTATCAGGAAACTTAAAATATAATGATATACAATGCTCAGTAAATGTATCGTGTCTCATTAAAAATTTGGCAACGAGTACATCTACTATATTAACATCTAAACATAAGACTTATTCTCTATATCGGTCCATGTGTATTGCTATAATAGGATACGATTCTATTATATGGTATAAATATATAAATGACAGGTATAATGACATCTATGATTTTACTGCAATATGTATGCTAATAGCGTCTACATTGATAGTGATCATATACGTGTTTAAAAAAATAAAAATGAACTCTTAATTATGTTATACTATTAGAAATGGATAAAATCAAAATTACGATTGATTCAAAAATTGGTAATGTTGTTACCATATCGTATAACTTGGAAAAGATAACTATTGATGTCACGCCAAAAAAGAAAAAAGAAAAGGATGTATTATTAGCGCAATCAGTTGCTGTCGAAGAGGCAAAAGATGTCAAGGTGGAAGAAAAAAATATTATCGATATTGAAGATGACGATGATATGGATATAGAAAACACGTAATACGATCTATAAAAATAAGTATTAAATACTTTTTATTTACGGTACTCTTGTAGTGGTGATACCACTAATCGATTATTTTTTTTAAAAAAATACTTATTCTGATTCTTCTAGCCATTTCCGTGTTCGTTCGAATGCCACATCGACGTCAAAAATAGGGGAGTAGTTGAAATCTAGTTCTGCATTGTTGGTACGCACCTCAAATGTAGTGTTGGATATCTTCAACGTATAGTTGTTGAGTATTGATGGTTTTCTAAATAGAATTCTCTTCATATCATTCTTGCACGCGTACATTTTTAGCATCCATCTTGGAATCCTAGATCCTTGTTCTATTCCCAATGGTTTCATCAATAGAAGATTAAACATATCGTAAGAACACGATGGAGAGTAATCGTAGCAAAAGTAAGCATTTCCTTTAATCGCAGATCCCGGATACTGGATATATTTTGCAGCCAACACGTGCATCCATGCAACATTTCCTACATATACCCGGCTATGCACAGCGTCATCATCGACTGTACGATACATAATGTTACCGTGTTGCTTACATTGCTCGTAAAAGACTTTCGTCAATTTGTCTCCTTCTCCGTAAATTCCAGTGGGTCTTAGGCAACAAGTATACAATTTTGCGCCATTCATGATTACGGAATTATTGGCTTTCATAACCAGTTGCTCGGCCATACGTTTACTTTTTGCGTATACATGTCCTGGTGATATATCATAAAGGGTATGCTCATGACCGATGAATGGATTACCGTGTTTATTTGGTCCTATTGCTTCCATGCTACTAGTATAGATCAAATACTTGATTCCTAGGTCCACACAAGCTGCCAATATAGTCTGTGTTCCATAATAGTTTACTTTCATGATTTCATTATCAGTGTATTTTCCAAATACATCCACTAGAGCAGCCGTATGAATAATCAGATTTACCCCATCTAGCGCTTCTCTCACCTTATCAAAGTCGTTTATATCACATTGTATATAGTTTATAACCTTAACTTTCGAGGTTATTGGTTGTGGATCTTCTACAATATCTATGACTCTTATTTCTTGAACATCATCTGCGCTAATTAAAAGTTTTACTATATACCTGCCTAGAAATCCGGCACCGCCAGTAACCGCGTACACGGCCATTGCTGCCACTCATAATATCAGACTACTTATTCTATTTTACTAAATAATGGCTGTTTGTATAATAGACCACGATAATATCAGAGGAGTTATTTACGTTGAACAAGTCCATGGAAAAGATAAAGTTTTAGGATCAGTTATTGGATTAAAATCCGGAACGTATAGTTTGATAATTCATCGTTACGGAGATATTAGTCGAGGATGTGATTCCATAGGCAGTCCAGAAATATTTATCGGTAACATCTTTGTAAACAGATATGGTGTAGCATATGTTTATTTAGATACAGATGTAAATATATCTACAATTATTGGAAAGGCGTTATCTATTTCAAAAAATGATCAGAGATTAGCGTGTGGAGTTATTGGTATTTCGTACATAAATGAAAAGATAATACATTTTCTTACAATTAACGAGAATGGCGTTTGATATATCAGTTAATGCGTCTAAAACAATAAATGCATTAGTTTACTTTTCTACTCAGCAAGATAAATTAGTCATACGTAATGAAGTTAATGATATACACTACACTGTCGAATTTGATAGGGACAAAGTAGTTGATACGTTTATTTCATATAATAGACATAATGACTCCATAGAGATAAGAGGGGTGCTTCCAGAGGAAACTAATATTGGTCGCGTGGTTAATACGCCGGTTAGTATGACTTACTTGTATAATAAGTATAGTTTTAAACCGATTTTAGCAGAATATATAAGACACAGAAATACTATATCCGGCAACATTTATTCGGCATTGATGACGCTAGATGATTTGGTTATTAAACAGTATGGAGACATTGATCTATTATTTAATGAGAAACTTAAAGTAGACTCCGATTCGGGACTATTTGACTTTGTCAACTTTGTAAAGGATATGATATGTTGTGATTCTAGAATAGTAGTAGCTCTATCTAGTCTAGTATCTAAACATTGGGAATTGACAAATAAAAAGTATAGGTGTATGGCATTAGCCGAACATATAGCTGATAGTATTCCAATATCTGAGCTATCTAGACTACGATACAATCTATGTAAGTATCTACGCGGACACACTGATAGCATAGAGGATGAATTTGATTATTTTGAAGACGATGATTTGTCTACATGTTCTGCCGTAACCGATAGGGAAACGGATGTATAATTTTTTTTATAGTATGAAGGATATGATGGATATGATGATATGATGGATATGATGATATGATGGATATGATGGATATGATGGATATGATGGATATGATAAAAAAATATAATTGTTGTATCCATTCCCATTCAAATCACCTTATATGATTCTGTAACACAATGAAGGAGTCTCATAGATATATAGAGGTCAGATACTGGTTTGATAAACTTTTTATTCCACATGAGCATGTTTGACTTATGGTTAGACACACATACTTTAACAAATCACTGAAAATTGGAGTTAGGTATTCCTCTCAGAATCAGTTGCCGTTCTGGAACATTAAATGTATTTTTTATGATATACTCCAACGCATTTATGTGGGTATACAACAAGTCATTAATAATGAGTATTTCCAAGAGTTTTAGTTGTCTAGTATTTAACAAGAGAAGAGATTTCAACAGACTGTTTATGAACTCGAATACCGCCTCATTGTCGCTTATATTGATGACATGACATCGAATTCCCAATATCAATCTCATCAGTGATGAGTAGCTCAATCTTGTTATCGGGATCCAATTTCTAAAGATGTCATTAAACCCTCGATCGTGAATGGATTTATCATCATCGTTTTTATGTTGGACATGAGCTTAGTCCGTTTGTCCACATCTATATACGATGATTTCTGAATTATTTCATATATCTCTCGTTAACTCCAGGAACTTGTCAGGGATCTAACTTTAATATGTTCTCGTCTAAGAGATGAAAATCTTTGGATGGTTGCATGTGACTTTTCTCTAAAGGATGATGTTACCCGATCCTCTCTTAAATGACTCCATCTTATCCTTGGACAAGATGGACAGTCTATTTTCCTTAGATGGTTTAATATTTTTTACCCATGATCTATAAAGGTAGACAGACCTAATCGTCTCGGATGACCATATATTATTTTCCGTTTTATTATACGCATAAATTGTAAAAAATATGTTAGGTTTACGAAAATGTCTCGTGGGGCATTAATCGTTTTTGAAGGATTGGACAAATCTGGAAAAACAACACAATGTATGAACATCATGGAATCTATACCGGCAAACACGATAAAATATCTTAACTTTCCTCAGCGATCCACAGTCACTGGAAAGATGATAGATGACTATCTAACTCGTAAAAAAACCTATAATGATCATATAGTTAATCTATTATTTTGTGCAAATAGATGGGAGTTTGCATCTTTTATACAAGAACAACTAGAACAGGGAATTACTTTAATAGTTGACAGATACGCGTTCTCTGGAGTAGCGTATGCCACCGCTAAAGGCGCGTCAATGACTCTCAGTAAGAGTTATGAATCTGGATTGCCTAAACCCGACTTAGTTATATTCTTGGAATCTGGTAGCAAAGAAATTAATAGAAACATCGGCGAGGAAATTTATGAAGATGTTGAATTCCAACAAAAGGTATTACAAGAATATAAAAAAATGATTGAAGAAGGAGATATTCATTGGCAAATTATTTCTTCTGAATTCGAGGAAGATGTAAAGAAGGAGTTGATTAAGAATATAGTTATAGAGGCTATACACACGGTTACTGGACCAGTGGGGCAACTGTGGATGTAATAAAATGAAATTACATTTTTATAAATAGATGTTAGTACAGTGTTATAAATGGATGAAGCATATTACTCTGGCAACTTGGAATCAGTACTCGGGGATACGTGTCCGATATGCATACCGAACTCGCATCAATATCTCAATTAGTTATTGCCAAGATAGAAACTATAGATAATGATTATTAAACAAGGACATTGTAAATTTTATCATGTGTAGATCAAACTTGGATAATCCATTTATCTCTTTCCTAGATACTGCATATACTATCATAGATCAAGAGATCTATCAGAACGAGTTGATTAATTCATTAGACGATAATGAAATTATCGATTGTATAGTTAACAAGTTTATGAGCTTTTATAAGGATAACCTAGAAAATATGGTAGATGCTATCATTACTCTAAAATATTATAATTAATAATCCAGATTTTAAAACTACGTATGTGGAAGTACTCGGTTCCAGAATAGCTGATATAGATATTAAACAAGTGATACGTAAGAATATAATACAATTGTCTAATGATCCGCGAACGATATTTGTGAAAATATTAAAAAAAAATACTTTTTTTATTAAATGACGTCTCTTCGCGAATTTAGAAAATTATGCTGTGATATATATCACGCATCAGGATATAAAGAAAAATCTAAATTAATTAGAGACTTTATAACAGATAGAGATGATACCGATACATATTTGATCATTAAGCTATTGCTTCCCGGATTAGACGATAGAATGTATAACATGAACGATAAACAAATTATAAAATTATATAGTATAATATTTAAACAATCTCAGGAAGATATGCTACAAGATTTAGGATACGGATATATAGGAGACACTATTAGGACTTTCTTCAAAGAGAACACGGAAATCCGTCCACGAGATAAAAGCATTTTAACTTTAGAAGAAGTGGATAGTTTTTTAACTACGTTATCATCAGTAACTAAAGAATCACATCAAATAAAATTATTGACTGATATAGCATCTGTTTGTACATGTAATGATTTAAAATGTGTAGTCATGCTTATTGATAAAGATCTAAAAATTAAAGCGGGTCCTCGGTACGTGCTTAACGCTATTAGTCCTCATGCCTATGATGTTTTTAGAAAATCTAATAACTTGAAAGAGATAATAGAAAATGCAGCTAAACAAAATCTAGACTCTATATCTATTTCTGTTATGACTCCAATTAATCCCATGTTAGCGGAATCATGTGATTCTGTCAATAAGGCGTTTAAAAAATTTCCATCAGGAATGTTTGCGGAAGTCAAATACGATGGTGAAAGAGTACAAGTTCATAAAAAAAATAACGAGTTTGCATTCTTTAGTAGAAACATGAAACCAGTACTCTCTCATAAAGTGGATTATCTCAAAGAATACATACCGAAAGCATTTAAAAAAGCTACGTCTATCGTATTGGATTCTGAAATTGTTCTTGTAGACGAACATAATGTACCGCTACCGTTTGGAAGTTTAGGTATACACAAAAAGAAAGAATATAAAAACTCTAACATGTGTTTGTTCGTATTTGACTGTTTATACTTTGATGGATTCGATATGACAGACATTCCATTGTATGAACGAAGATCTTTTCTCAAAGATGTTATGGTCGAAATACCCAATAGAATAGTATTCTCAGAGTTGACGAATATTAGTAACGAGTCTCAGTTAACTGATGTATTAGATGATGCACTAACGAGAAAATTAGAAGGATTGGTCTTAAAAGATATTAATGGCGTATACGAACCGGGAAAGAGAAGATGGTTAAAAATAAAGCGAGACTATTTGAACGAGGGTTCCATGGCAGATTCTGCCGATTTAGTAGTACTAGGTGCCTACTATGGTAAAGGAGGAAAGGGTGGTATCATGGCAGTCTTTCTAATGGGTTGTTACGACGATGAATCCGGTAAATGGAAGACGGTAACTAAATGTTCCGGTCACGATGATAATACGTTAAGGGTTTTGCAAGACCAATTAACGATGGTTAAAATTAACAAGGATCCCAAAAAAATTCCAGAGTGGTTGGTAGTTAATAAAATCTATATTCCCGATTTTGTAGTAGATGATCCGAAACAATCTCAGATATGGGAAATTTCAGGAGCAGAGTTTACATCTTCCAAGTCACATACAGCGAATGGAATATCGATTAGATTTCCTAGATTTACTAGGATTAGAGAAGATAAAACGTGGAAAGAATCTACTCATCTAAACGATTTAGTAAACTTGACTAAATCTCTTAATAGTTACATATAAACTGAAAAATAAAATAACACTATTTTAGTTGGTAGTCGCCATGGATGGTGTTATCGTATACTGTCTAAATGCGTTAGTAAAACATGGCGAGGAAATAAATCATATAAAAAATGATTTCATGATTAAACCATGTTGTGAAAGAGTTTGTGAAAAAGTCAAGAACGTTCACATCGGCGGACAATCTAAAAACAATACAGTGATTGCAGATTTGCCATATCTGGATAATGCTGTATCAGATGTATGCAAATCAATATATAAAAAGAATGTATCAAGAATATCCAGATTTGCTAATTTGATAAAAATAGATGACGATGACAAGACTCCTACCGGCGTATATAATTATTTTAAACCTAAAGATGCTATTCCTGTTATTATATCCATAGGAAAGGATAAAGATGTCTGTGAACTATTAATCTCATCTGATAAAGCGTGTGCGTGTATAAAGTTAAATTTATATAAAGTAGCCATTCTTCCCATGGATGTTTCCTTTTTTACCAAAGGAAATGCATCATTGATTATTCTCCTGTTTGATTTCTCTATCGATGCGGCACCTCTCTTAAGAAGTGTAACCGATAATAATGTTATTATATCTAGACACCAGCGCCTACATGACGAGCTTCCGAGTTCCAATTGGTTCAAGTTTTACATAAGTATAAAGTCCGACTATTGTTCTATATTATATATGGTTGTTGATGGATCTATGATGTATGCGATAGCTGATAATAGAACTCACGCAATTATTAGCAAAAATATATTAGACAATACTACGATTAACGATGAGTGTAGATGCTGTTATTCTGAACCACAGATTAGGATTCTTGATAGAGATGAGATGCTCAATGGATCATCGTGTTATATGAACAGACATTGTATTATGATGAATTTACCTGATGTAGGCGAATTTGGATCTAGTATGTTGGGGAAATATGAACCTGACATGATTAAGATTGCTCTTTCGGTGGCTGGTAATTTAATAAGAAATCGAGACTACATTCCCGGGAGACGAGGCTATAGCTACTACGTTTACGGTATAGCCTCTAGATAATTTTTTTTAAGCACGAAATAAAAACATAATTTTAAACAATCTATTTCATACTATTTTGTGTGCTCACCATGAACATAAAGATAGATATATTAGTATTTCTGGTGATAAATTTACGGCGACTGCTAGGAGGGAAAATGAAGAAAGAAAAAATATCTACCTCTCCAAAAAGAAAAACTACTGATGTTATCAAACCTGATTATCTTGAGTACAATGACTTGTTAGATAGAGATGAGATGTCTACTATTCTAGAGGAATATTAGGCCTTAGAATAAAATATGGACGACTCTTAACGAAATTAGAAAATTCGATAATGATGTTGAAGAACAATTCGGTACTATAGAAGAACTCAAGCAGAAGCTTAGATTAAATTCTGAAGAGAGAGCAGATAATTTTATAGATTATATAAAGGTACAAAAACAGGATATCATCAAACTTACTGTATACGATTGCATATATCTATGATAGGATTGTGTGCGTGCGTGGTAGATGTTTGGAGAAATGAGAAACTGTTTTCTAGATGGAAATATTGGTTACAAGCGATTAAACTGTTTATTGATGATCACATGCTTGATAAGATAAAATCTATTGTAGAATAGACTAGTGTATGTGGAAATGTCATAGAAAGTTAAAAGTTAATGAGAGCAAAAATATATAAGGTTGTATTCCATATTTGTTATTTTTTTCTGTAATAGTTAGAAAATACATTCGATGGTCTATCTACCAGATTATTATGTGTTATAAGGTACTTTTCTCATAATAAACTAGAGTATGAGTAAGATAGTGTTTTTCAAAAACATATAAATCTAAAATTGATGGATGAGATATACAGCTATTAATTTCGAAAATATATTTTAATCTGATAACTTTAAACATGGATTTTTGATGGTGGTTTAAGTTTAAAAAAGATTTTGTTATTGTAGTATGATAATATCAAAAAGATGGATATAAAGAATTTACTGACTACATGTACTATTTTACATTACTACATTGGCTACGGCATATATACCTATTTCGTCACTTCCACACGCTCCGGTAAACGGGTGTCATGTGACGAGGGAGAATCTTGATAAGAGGCATAATCAATGTTGTAATCCGATGTCCACCTGGAGAATTTGCCAAGGTCAGATGTAGAGTTGGTAGTGATAACACAAAATGTGAACACTGCCCACCTCATACATATACCGCAATCCCCAATTATTCTAATAGATGTCATCAATGTAGAAAATGCCCAACAGGATCATTTGATAAGGTAAAGTGTACCGGAACACAGAACAAATGTTCGTGTCATCCTGGTTGGTATACGCTACTGATTCTTCACAGACTGAAGATTGTCGAGATTTGTGTACCAAAAAAGGAGATGTCCATGCGGATACTTTGGTGGAATAGATGAAGGAAATCCTATTTGTAAATCGTGTTGTGTTGGTGAATATTGCGACTACCTACGTAATTATAGACTTGATCCATTTCCTCCATGCAAACTATCTATCTAAATGTAATTAATTATGATTTTGATGATAATGTTACCATACATTATATCACTACTTGGTTAGTGTGTATTATTTAGTATGGAAGACCTATTAATAATTACTTATCTTTTGACGATCTTGTTATAATTATAATATAAAAATACTTATGACATAGTAACTCATAATTGCTGACGCGATAAATTCGTAATAATCTGTTTTGTTCAAATTTTTATAAGGAATCTACAGGCATAAAAATAAAAATATAATCTATAATATACTCTTACAACGCCATCATGAATAGCAGTGAATTAATTGCTGTTATTATGGATTTAGAAATAGTGGACGATTTTGTGATATTAATATAGTTATTAATGATGAAAGGATAAACGCGCATAGACTCATCCTATCTGGAGCCTCCGAATATTTTTTCCATTCTGTTTTCCAATAATTTTATCGATTCTAATGAATACGAAGTTAATCTAAGTCATTTAGATTATCAAAGTGTTAACTATTTGATCGATTACATTTATGGGATACCTTTGAGCCTAACTAACAATAACGTGAAATATATTCTTTCAACCGCTGATTTTTTTACAAATTGGATCTGTCATTACTGAGTGCGAAAAATACATACTTAAAAATCTTTGTTTTAGAAACTGTATCGATTTCTACATATACGCTGATAAATATAATAACAAGAAAATAGAATTAGCATCGTTTAACACAATATTACGAAATATTTTGAGACTCATCAACAATGAAAACTTTAAATACTTAACAGAGGAATCAATGATAAAAATTTTAAGCGATGATATGTTATATATAAAAAATGAGGATTTCACCCCACTGATTCTCATTAAATGGTTAGAGAGTACACCAACCATGTACCGTCGAGTTACTTAGATGCCTCAGAATATCATTTCTTTCCCCACAAGTTATAAAATCACTTTATAGTCATCGACTGGTTAGTTCAATCTACGAATGTATAACATTCTTAAACAATATAGCATTCTTGGATAAATCATTTCCTAGATACCATATCATCGAGTTGATATCTATCGGTATAAGTAATTCACATGATAAGATTTCCATAAACTGCTACAATCATAAAAAAATTCATGGGAAATGATATCTTCACGTAGATATAGGTGTAGTTTCGCAGTGACCGTCCTGGATAATATTATCTATATGATGGGTGGATATGATCAGTCCCTGTATAGAAGTTCAAAGGTTATAGCGTACAATACATGTACTAATTCTTGGATATATGATATACCAGAGCTAAAAATATCATCGTTCTAATTGCGGAGGAGTTGCCAATGACGAATACATTTATTGTATAGGCGGTATACGCGATCAGGAGTCATCGTTGATATCTAGTATCGATAGATGGAAGCCATCAAAACCATATTGGCAGAAGTATGCTAAAATGTGCGAACCAAAATGTGATATGGGGTTGCGATTTTAAACGGATTAATATATGTCATAGGTGGAGTCGTTAAAGGTGACACACATATACCAACGCACTAGAGAGTTTATCAGAAGATGGATGGATGAATCATCAACGTCTTCCAATAAAAATGTCCAATATGTCGACGATTGTTCATGCTGGAAAGATTTATATATCTAGAGGTTACAACAATAGTAGTGTAGTTAATGTAATATCGAATCTAGTCCTTAGCTATAATCCGATATATGATGAATGGACCAAATTATCATCATTAAATATTCCTAGAATTAATCCTGCTCTATGGTCAGTGTATAATAAATTATATGTAGGAGGAGTAATATCTGATGATGTTCAAACTAATACATCTGAAACATACGATAAAGAAAAAGATTGTTGGACATTGGATAATGGTCACTTGTTACCACATAATTATATAATGTATAAATGCGAACCGTTTAAACATAGATATCCATTGGAAAAAACACAGTACACGAATGATTTTCTAAAGTATTTGGAAAGTTTTATAGGTAGTTGATAGAACAAAATACATAATTTTGTAAAAATAAATCACTTTTTATACTAATATGACACAATTACCAATACTTTTGTTACTAATATCATTAGTATACGCTACACCTTCTCCTCAGACATCTAAAAAAATAGGTGATGATGCAACTATATCATGTAGTCGAAATAATACAAATTACTACGTTGTTATGAGTGCTTGGTATAAGGAGCCCAATTCCATTATTCTCTTAGCTGCCAAAAGCGACGTCTTGTATTTTGATAATTATACCAAGGATAAAATATCTTACGACTCTCCATACGATGATCTAGTTACAACTATCACAATTAAATCATTGACTGCTGGAGATGCCGGTACTTATATATGTGCATTCTTTATGACATCGACTACAAATGATACTGATAAAGTAGATTATGAAGAATACTCCATAGAGTTGATTGTAAATACAGATAGTGAATCGACTATAGACATAATACTATCTGGATCTACACCAGAAACTATTTCTGAGAAACCAGAGGATATAGATAATTCTAATTGCTCGTCTGTATTCGAAATCACGACTCCGGAACCAATTACTGATAATGTAGACGACCATACAGACACCGTCACATACACTAGTGATAGCATTAATACAGTAAATGCATCATCTGGAGAATCCACAACAGACGAGATTCCGGAACCAATTACTGATAAAGAAGAAGATCATACAGTAACAGACACTGTCTCATACACTACAGTAAGTACATCATCTGGAATTGTCACTACTAAATCAACCACCGATGATGCGGATCTTTATGATACATACAATGATAATGATACAGTACCGCCAACTACTGTAGGTGGTAGTACAACCTCTATTAGCAATTATAAAACCAAGGACTTCGTAGAAATATTTGGTATTACCACATTAATTATATTGTCAGCAGTGGCGATTTTCTGTATTACGTATTATATATGTAATAAACACCCACGTAAATACAAAACAGAGAACAAAGTCTAGATTTTTGACTTACATAAATATCTGGGATAATAAAATCTATCATATTGAGAGGACCATCTGGTTCAGGAAAGACAGCCATAACCAAAAGACTGTTAAAAGACTATGGGAATATATTTGGATTTGTGGTGTCCCATACCACTAGATTTCCTCGTCCTATGGAACGAGAAGGTGTTGATTACCTTACGTTAACAGAGAGGCCATCTGGAAGGGAATAGCCGCCGGAAACTTTCTAGAACATACTGAGTTTTTAGGAAATATTTACGGAACTTCTAAAACAGCTGTAAATACAGCGGTTATTAATAATCGTATTTGCGCGATGGATTTAAACATCAACGGTGTTAGAAGTCTTAAAAATACTTACCTAATGCATTACTTGGGTATATAAGACCTACCTCTCTTAAAATGGTTGAGACCAATCTTCGTCGTAGAAACACTGAAGCGGACGACGAATCTCATCGTCGCGTGATGTTGGCAAAAAACGGATATGGATGAGGTCAACGAAGCAGGTCTATTCGACACTATTATTATTGAAGATGATGTGAATTTAGCATATAGTAAGTGTTAATTCAGATACTACAGGACCGTATTAGAATGTATTTTAACACTAATTAGAGACTTAAGATTTGACTTAAAACTTGATAATTAATAATATAACTCGTTTTTATATGTGGCTATTTCAACGTCTAATGTATTAGTTAAATATTAAAACTTACCACGTAAAACTTAAAATTTAAAATGGTATTTCATTGACAGATCATACATTATGAAGTTTCAAGGACTTGTGTTAATTGACAATTGCAAAAATCAATGGGTCGTTGGACCATTAATAGGAAAAGGTGGATTCGGTAGTATTTATACTACTAATGACAATAATTATGTAGTAAAAATAGAGCCCAAAGCTAACGGATCATTATTTACCGAACAGGCATTTTATACTAGAGTACTTAAACCATCCGTTATCGAAGAATGGAAAAAATCTCACAATATAAAGCACGTAGGTCTTATCACATGCAAGGCATTTGGTTTATACAAATCCATTAATGTGGAATATCGATTCTTGGTAATAAATAGATTAGGTGCAGATCTAGATGCGGTGATCAGAGCCAATAATAATAGACTACCAGAAAGGTCGGTGATGTTGATCGGAATCGAAATCTTAAATACCATACAATTTATGCACGAGCAAGGATATTCTCACGGAGATATTAAAGCGAGTAATATAGTCTTGGATCAAATAGATAAGAATAAATTATATCTAGTGGATTACGGATTGGTTTCTAAATTCATGTCTAACGGCGAACATGTTCCATTTATAAGAAATCCAAATAAAATGGATAACGGTACTCTAGAATTTACACCTATAGATTCGCATAAAGGATACGTTGTATCTAGACGTGGTGATCTAGAAACACTTGGATATTGTATGATTAGATGGTTGGGAGGTATCTTGCCATGGACTAAGATATCTGAAACAAAGAATTCTGCATTAGTAAGTGCCGCAAAACAGAAATATGTTAACAATACTGCGACTTTGTTAATGACCAGTTTGCAATATGCACCTAGAGAATTGCTGCAATATATTACCATGGTAAACTCTTTGACATATTTTGAGGAACCCAATTACGACGAGTTTCGTCGAGTATTAATGAATGGAGTTATGAAAAATTTTTGTTGATAAAAAAATTAAAAAAATAACTTAGTTATTATCACTCTCGTGAGTACAATAGAAACATGGCGATGTTTTACGCACACGCTTTCGGTGGGTACGACGAGAACCTTCATGCATTTCCTGGAATATCATCGACGGTTGCCAATGATGTCAGGAAATATTCTGTTGTGTCAGTTTATAATAAAAAGTATAACATTGTAAAAAACAAATATATGTGGTGTAACAGTCAAGTGAACAAGAGATATATTGGAGCACTACTGCCTATGTTTGAATGCAATGAATATCTACAAATTGGAGATCCAATCCATGATCTAGAAGGAAATCAAATCTCTATTGTCACATATCGCCACAAAAACTACTATGCTCTAAGTGGAATTGGGTACGAGAGTCTAGACTTGTGTTTGGAAGGAGTAGGGATTCATCATCACGTACTTGAAACAGGAAACGCGGTATATGGAAAAGTTCAACATGAGTATTCTACTATCAAAGAGAAGGCCAAAGAAATGAATGCACTCAAACCAGGACCTATCATCGATTACCACGTCTGGATAGGAGATTGTGTCTGCCAAGTTACTACTGTAGACGTGCATGGAAAGGAAATTATGAGAATGAGATTCAAAAGGGGTGCGGTGCTTCCGATTCCAAATCTGGTAAAAGTTAAAGTTGGGGAGGAAAATGATACAATAAATCTTTCCACTTCCATATCAGCTCTCCTAAATTCCGGTGGCGGCACCATCGAGGTAACATCTAAGGAAGAACGTGTAGATTATGTACTCATGAAACGTTTGGAATCTATACATCATTTGTGGTCTGTAGTGTATGATCATCTTAATGTTGTGAATGGCGAAGAACGATGTTATGTACATATGCATTCATCTCATCAAAGTCCTATGCTGAGTACTGTAAAAACAAATTTGTACATGAAGACTATGGGAGCATGTCTTCAAATGGACTCCATGGAAGCTCTAGAGTATCTTAGTGAACTGAAGGAATCAGGTGGGCGGAGTCCCAGACCAGAATTGCAGAAATTTGAATATCCAGATGGAGTGAAAGACACTGAATCAATTGAGAGATTGGCAGAGGAGTTCTTCAATAGATCAGAACTTCAGGCCGGTGAATCAGTCAAATTTGGTAATTCTATTAATGTTAAACATACATCTGTTTCAGCTAAGCAACTAAGAACACGTATACGACAGCAGCTTCCTTCTATACTCTCATCTTTTGCCAACACAAAGGGTGGATATTTGTTCATTGGAGTTGATAATAATACACACAAAGTAATTGGATTCACGGTGGGTCATGACTACCTCAAACTGGTAGAGAGTGATATAGAAAAGTATATCCAAAAACTTCCTGTTGTGCATTTCTGCAAGAAAAAAGAGGACATCAAGTACGCATGTAGATTCATCAAGGTGTATAAACCTGGTGATGAGACTACCTCGACATATGTGTGCGCAATCAAAGTGGAAAGATGCTGCTGTGCTGTGTTTGCGGATTGGCCAGAATCATGGTACATGGATACTAGTGGTAGTATGAAGAAGTATTCTCCAGATGAATGGGTGTCACATATAAAATTTTAATTAGGGTAAGGTAAAACTATATATAATAACTAACAATTTGTGTATCATATAGACAATTAATTAGGTAACTGTTATCTCTTTTTAACTAACTAACTAACTAACTAACTCTTATATACTATTAATAATACATCTATTAATCATTGATTAGCTTATTGCTTTAATTGTTTTTGTAAACTAACACTGTTCATTGAAAAGGGATAACATGTTACAGAATATAAATTATATATGGATTTTTTTAAAAAGGAAATACTTGACTGGAGTATATATTTATTTCTTCATTACATAACACGTCTGTGTTCTAATTCTTCCAATTCTTCCACATCTCATATAATACAGGAATATAATCTTGTTCGAAAATATGAGAAAGTGGATAAAACAATAGTTGATTTTTTATCTAGGTGGCCAAATTTATTCCATATTTTAGAATATGGGGAAAATATTCTACATATTTATTTTATAGATGCTGCTAATACGAATATTATGATTTTTTTTCTAGATAGAGTATTAAATATTAATAAGAACCGTGGGTCATTTATACATAATCTCGGGTTATCATCCATTAATATAAAAGAATATGTATATCAATTAGTTAATAATGATCATCTAGATAATAGTATAAGACTAATGCTTGAAAATGGACGTAGAACAAGACATTTTTTGTCTTATATATTGGATACAGTTAATATCTATATAAGTATTTTAATAAATCATAGATTTTATATAGATGCCGAAGACAGTTACGGTTGTACATTATTACATAGATGTATATATAACTATAAGAAATCAGAATCAGAATCATATAATGAATTAATTAAGATATTGTTAAATAATGGATCAGATGTAGATAAAAAAGATACGTACGGAAACACACCGTTTATCCTATTATGTAAACACGATATCGACAACGCGGAATTGTTTGAGATATGTTTAGAGAATGCTAATATAGACTCTGTAGACTTTAATGGATATACACCTCTTCATTATGTCTCATGTCGTAATAAATATGATTTTGTAAAGTTATTAATTTCTAAAGGAGCAAATGTTAATGCACGTAATAGATTCGGAACTACTCCATTTTATTGTGGAATTATACACGGTATCTCGCTTATAAAACTATATTTGGAATCAGACACAGAGTTAGAAATAGATAATGAACATATAGTTCGTCATTTAATAATTTTTGATGCTGTTGAATCTTTAGATTATCTATTGTCCAGAGGAGTTATTGATATTAACTATCGTACTATATACAACGAAACATCTATTTACGACGCTGTCAGTTATAATGCGTATAATACGTTAGTCTATCTATTAAACAGAAATGGTGATTTTGAGACGATTACTACTAGTGGATGTACATGTATTTCGGAAGCAGTCGCGAACAACAACAAAATAATAATGGATATACTATTGTCTAAACGACCATCTTTGAAAATTATGATACCATCTATGATAGCAATTACTAAACATAAACAACATAATGCAGATTTATTGAAAATGTGTATAAAATATACTGCGTGTATGACCGATTATGATACTCTTATAGATGTACAATCGCTACATCAATATAAATGGTATATTTTAAAATGTTTTGATGAAATAGATATCATGAAGAGATGTTATATAAAAAATAAAACTGTATTCCAATTAGTTTTTTGTATCAAAGACATTAATACTTTAATGAGATACGGTAGACATCCTTCTTTCGTGAAATGTAATATTCTTGACGTATACGGAAGTTGTGTACGTAATATCATAGCATCTATTAGATATCGTCAGAGATTAATTAGTCTATTATCCAAGAAGCTGGATGCTGGAGATAAATGGTCGTGTTTTCCTAACGAAATAAAATATAAAATATTGGAAAACTTTAACGATAACGAACTGACCACATATCTGAAAATCTTATAAACACTATTAAAATATAAAATCTAAGTAGGATAAAATCACACTACATCATTGTTTCCTTTTAGTGCTCGACAGTGTATACTATTTTTAACACTCATAAATAAAAATGAAAACGATTTCCGTTGTTACGTTGTTATGCGTACTACCTGCTGTTGTTTATTCAACATGTACTGTACCCACTATGAATAACGCTAAATTAACGTCTACCGAAACATCGTTTAATGATAAACAGAAAGTTACGTTTACATGTGATTCAGGATATCATTCTTTGGATCCAAATGCTGTCTGTGAAACAGATAAATGGAAATACGAAAATCCATGCAAGAAAATGTGCACAGTTTCTGATTATGTCTCTGAACTATATGATAAGCCATTATACGAAGTGAATTCCACCATGACACTAAGTTGCAACGGTGAAACAAAATATTTTCGTTGTGAAGAAAAAAATGGAAATACTTCTTGGAATGATACTGTCACGTGTCCTAATGCGGAATGTCAACCTCTTCAATTAGAACACGGATCGTGTCAACCAGTTAAAGAAAAATACTCATTTGGGGAATATATGACTATCAACTGTGATGTTGGATATGAGGTTATTGGTGTTTCGTATATAAGTTGTACGGCTAATTCTTGGAATGTTATTCCATCATGTCAACAAAAATGTGATATACCGTCCCTATCTAATGGATTAATTTCCGGATCTACATTTTCTATCGGTGGCGTTATACATCTTAGTTGTAAAAGTGGTTTTACACTAACGGGGTCTCCATCATCCACATGTATCGACGGTAAATGGAATCCCATACTCCCAACATGTGTACGATCTAACGAAGAATTTGATCCAGTGGATGATGGTCCCGACGATGAGACAGATCTGAGCAAACTCTCGAAAGACGTTGTACAATATGAACAAGAAATAGAATCGTTAGAAGCAACTTATCATATAATCATAATGGCGTTGACAATTATGGGTGTCATATTTCTAATCTCCATTATAGTATTAGTTTGTTCCTGTGACAAAAATAATGACCAATATAAGTTCCATAAATTGCTACCGTGAATATAAATCCGTTAAAATAATTAATAATTAATAATTAATAACGAACAAGTATCAAAAGATTAAAGAATTAGCTAGAATCAATTAGATGTCTTCTTCAGTGGATGTTGATATCTACGATGCCGTTAGAGCATTTTTACTCAGGCACTATTATGACAAGAGATTTATTGTGTATGGAAGAAGTAACACCATATTACATAATATATACAGGCTATTTACAAGATGCACCGTTATACCGTTCGATGATATAGTACGTACTATGCCAAATGAATCACGTGTTAAACAATGGGTGATGGATACACTTAATGGTATAATGATGAATGAATTCGATACTGTATGTGTGGGTACCGGACTACGATTCATGGAAATGTTTTTCGATTACAATAAAAATAATCCCAAAAATAGCATCAACAATCAAATAATGTATGATATAATTAATAGCGTAGCCATAATTCTAGCTAATGAGAGATATAGAAGCGCGTTTAACGACGATAGAATATACATCCGTAGAACTATGATGGACAAATTGTACGAATACGCATCTCTAACTACTATTGGTACGATCACTGGAGGTGTTTGTTATTTTATCTGTTGATGCATCTAGTTAGTTTGTATAAATAATTATTTCGATATACTAGTTAAAATTTTAAGATTTTAAATGTATAAAAAACTAATAACGTTTTTATTTGTAATAGGTGCAGTTGCATCCTATTCGAATAATGAGTACACTCCGTTTAATAAACTGAGTGTAAAACTCTATATAGATGGAGTAGATAATATAGAAAATTCATATACTGATGATAATAATGAATTGGTGTTAAATTTTAAAGAGTACACAATTTCTATTATTACAGAGTCATGTGACGTCGGATTTGATTCCATAGATATAGATGTTATAAACGACTATAAAATTATTGATATGTATACCATTGACTCGTCTACTATTCAACGCAGAGGACATACGTGTAGAATATCTACCAAATTATCATGCCATTATGATAAGTACCCTTATATCCACAAATATGAGGGTGATGAACGACAATATTCTATTACCGCAGAGGGAAAATGCTATAAAGGAATAAAATATGAAATAAGTATGATGAACGATGATACTCTATTGAGAAAACATACTCTTAAAATTGGATTTACTTATATATTCGATCGTCATGGGCATAGTAATACATATTATTCAAAATATGATTTTTAAAAATTTAAAATATATTATCACTTCAGTGACAGTAGTCAAATAACAAACAACACCATGAGATATATTATAATTCTCGCAGTTTTGTTCATTAATAGTATACATGCTAAAATAACTAGTTATAAGTTTGAATCCGTCAATTTTGATTCCAAAATTGAATGGACTGGGGATGGTCTATACAATATATCCCTTAAAAATTATGGCATCAAGACGTGGCAAACAATGTATACAAATGTACCAGAAGGAACATACGACATATCCGGATTTCCAAAGAATGATTTCGTATCTTTCTGGGTTAAATTTGAACAAGGCGACTATAAAGTGGAAGAGTATTGTACGGGACTATGTGTCGAAGTAAAAATTGGACCACCAACTGTAATATTGACTGAATATGACGATCATATCAATTTGTTCATCGAGCATCCGTATGCTACTAGAGGTAGCAAGAAGATTCCTATTTACAAACGCGGTGACATGTGTGATATCTACTTGTTGTATACGGCTAACTTCACATTCGGAGATTCTGAAGAACCAGTAACATATGATATCGATGACTACGATTGCACGTCTACAGGTTGCAGTATAGACTTTGCCACAACAGAAAAAGTGTGTGTGACAGCACAGGGAGCCACAGAAGGGTTTCTCGAAAAAATTACTCCATGGAGTTCGGAAGTATGTCTGACACCTAAAAAGAATGTATATACGTGCGCAATTAGATCTAAAGAAGATGTTCCCAATTTCAAGGACAAAATAGCCAGAGTTATCACGAGAAAATTTAATAAACAGTCTCAATCTTATTTGACTAAATTTCTCGGTAGCACATCGAATGATGTTACAACTTTTTTTAGCATTCTTGACTAAATATTCATAACTAATTTTTATTAATGATACAAAAATGAAATAAACTGTATATTATACACTGGTTAACGCCCTTGGCTCTAACCATTTTCAAGATGAGGTCCCTGATTATAGTCCTTCTGTTCCCCTCTATCATCTACTCAATGTCTATTAGACGATGCGAGAAGACTGAAGAGGAAACATGGGGATTAAAAATAGGGTTGTGTATAATTGCCAAAGATTTCTATCCCGAAAGAACTGATTGCAGTGTTCATCGCCCAACTGCAAGTGGAGGATTGATAACTGAAGGCAATGGATTCAGAGTAGTTATATATGATCAATGTACAGAACCCCATGACTTTATTATCACCGATACTCAACAAACACGTCTTGGATCATCTCATACATATATTAAATTCAGTAACATGAATACAGGTGTCCCATCTAGTATTCCAAAATGTTCCAGAACTCTCTGTATTTCTGTATATTGTGATCAAGAGGCGGGAGACATAAAATTTGAGGAGTATACTCAAGAATCAAGTGATATCAGTATTAGAGTTAAGTATGATTCATCATGTATTGATTATCTGGGTATTAATCAAAGTTTCATGAATGAATGTATTCGAAGAATTACAACATGGGATAGAGAATCATGCGTCAGAATTGATACACAGACTATAAATAAATATCTTAAGTCTTGCACCAACACAAAATTCGACCGTAATGTCTACAAAAGGTACATACTGAAGAGTAAAGCACTCCATGCTAAAACAGAGTTGTAATAGATATAAAATACTTTTTATAATAATTAGGCTAGAAAAATCTCACTCACATGTAATCTTAAAAAAATGATATGATAGTTCTTACAAGTAGCGATTGAGTTTTAAATGGATTCTATTAATTACCGGGGAACTTAACAATTCGTTCTGATCTACAGACATTGGTTAATAAATCATCTTATTTTGCCAATATATTAAAATGTGGAAACTCCACTAATAATATTACATTGTGCGACTTTCAAGATGATGTGATATATAGGGTTATACAGTTTTAACAATTATATAATAGAGATAGAAAGTACAAAAGATGTAGAATCAATGATATGGCACGCTAAACAGTTGGGTGTGGAATCATTGCTAAAAGAATGTCAAAATTATTTGCTTAGAATATTACGTATATAATTGTTTAGAAATTTATAGAATAACTAATATTAATACATTATCGTATATCTACAACGATATAAGAAACTTCATATTGGATAATATTACTATTAATATATAAGGATCCAGATTTTATATATTTGCCTAAATACATTATTATAGATTTACTAGGACAATCACCTAAATGTTTTTAACGAAGATAATGTGGTAAAGATTATATACACTTATATATCTTCCGATATCTACAAGGATATTCCATATCATCATTGTGTAAACTAAATAACGTTTTCTATGGCATTTAATAAGGACATTGGATATGTGGAAAAGTGATGTATGGAAGTTAGTACATTATCAACTTCTCCTTATTGATTGAAAATGAAAATATAAATAGTTTTTATGTATAGCGGTATCTACCCTATAGTTTTATTGCTTACTACTAACATGGATTCAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATACAGATGTAGAAGATATCATGAATGAAATAGATAGAGAGAAAGAAGAAATACTAAAAAATGTAGAAATTGAAAATAATAAAAACATTAACAAGAATCATCCCAGTGAATATATTAGAGAAGCACTTGTTATTAATACCAGTAGTAATAGTGATTCCATTGATAAAGAAGTTATAGAATATATCAGTCACGATGTAGGAATATAGATCATATCTACTAATTTTTATAATCGATACAAAACATAAAAACAACTCGTTATTACATAGCAGGTATGGAATCCTTCAAGTATTGTTTTGATAACGATGGTAAGAAATGGATTATCGGAAATACTTTATATTCTGGTAATTCAATACTCTATAAGGTCAGAAAAAATTTCACTAGTTCGTTCTACAATTACGTAATGAAGATAGATCATAAATCACACAAGCCATTGTTGTCCGAAATACGATTCTATATATCTGTATTGGATCCTTTGACTATCAACAACTGGACACGAGAACGTGGTATAAAGTATTTGGCTATTCCAGATCTGTATGGAATTGGAGAAACCGATGATTATATGTTCTTCATTATAAAGAATTTGGGAAGAGTATTCGCCCCAAAGGATAGTGAATCAGTTTTCGAAGCATGTGTCACTATGATAAACACGTTAGAGTTTATACACTCTCAAGGATTTACTCATGGAAAAATAGAACCGATGAATATACTGATTAGAAATAAACGTATTTCACTAATTGACTATTCTAGAACTAACAAACTATACAAAAGTGGAACACATATAGATTACAACGAGGACATGATAACTTCAGGAAATATCAATTATATGTGTGTAGACAATCATCTTGGAGCAACAGTTTCAAGACGAGGAGATTTAGAAATGTTGGGATATTGCATGATAGAATGGTTCGGTGGTAAACTTCCATGGAAAAACGAAAGTAGTATAAAAGTAATAAAACAAAAAAAAGAATATAAACAATTTATAGCTACTTTTTTTGAGGACTGTTTTCCTGAAGGAAATGAACCTCTGGAATTAGTTAGATATATAGAATTAGTATACATGTTAGATTATTCTCAAACTCCTAATTATGACAGACTACGTAGACTGTTTATACAAGATTGAAATTATATTCTTTTTTTTATAGAGTGTGGGGGTAGTGTTACGGATATCTAATATTAATATTAGACTATCTCTATCGCGCTACACGACCAATATCGATTACTATGGATATCTTCAGGGAAATCGCATCTTCTATGAAAGGAAAGAATGTATTCATTTCTCCAGCGTCAATCTCGTCAGTATTGACAATACTGTATTATGGAGCTAATGGATCCACTGCTGAACAGCTATCAAAATATGTAGAAAAGGAGGAGAACATGGATAAGGTTAGCGCTCAGAATATCTCATTCAAATCCATGAATAAAGTATATGGGCGATATTCTGCCGTGTTTAAAGATTCCTTTTTGGGAAAAATTGGCGATAAGTTTCAAACTGTTGACTTCACTGATTGTCGCACTATAGATGCAATCAATAAGTGTGTAGATATCTTTACTGAGGGAAAAATCAATCCACTATTGGATGAACCATTGTCTCCTGATACCTGTCTCCTAGCAATTAGTGCCGTATACTTTAAAGCAAAATGGTTGATGCCATTCGAAAAGGAATTTACCAGTGATTATCCCTTTTACGTATCTCCAACGGAAATGGTAGATGTAAGTATGATGTCTATTTACGGCGAGCCATTTAATCACGCATCTGTAAAAGAATCATTCGGTAACTTTTCAATCATAGAACTGCCATATGTTGGAGATACTAGTATGATGGTCATTCTTCCAAACAAGATTGATGGATTAGAATCCATAGAACAAAATCTAACAGATACAAATTTTAAGAAATGGTGTAACTCTCTGAAAGCTACGTTTATCGATGTGCACATTCCTAAGTTTAAGGTAATAGGTTCGTATAATCTTGTGGATACGCTAATAAAGTTGGGACTGACAGATGTGTTCTATTCAACTGGTGATTATATCAATATGTGTAATTCAGATGTGAGTGTTGACGCTATGATTCACAAAACGTATATAGATGTCAATGAAGAGTATACAGAAGCAGCTGCAGCAACTTCTGTACTAGTGGCAGACTGTGCATCAACAGTTACAAATGAGTTCTGTGCAGATCATCCGTTCATCTATGTGATTAGACATGTCGATGGTAAAATTCTTTTCGTTGGTAGATATTGCTCTCCAACAACTAATTAAGCACATTCTTAATATTAGAATATTATATAGTTAAGATTTTTACTAACAGGTTAACATTTTTTTTTAAAAATAGAAAAAACATGTGGTATTAGTGCAGGTCGTTATTCTTCCAATTGCAATTGGTAAGATGACGGCCAACTTTAGTACCCACGTCTTTTCACCACAACACTGTGGATGTGACAGACTGACCAGTATTGATGACGTCAGACAATGTTTGACTGAATATATTTATTGGTCGTCGTATGCATACCGCAACAGGCAATGCGCTGGACAACTGTATGACACACTCCTCTCTTTTAAAGATGATGCGGAATCAGTGTTCATCGACGTTCGTGAGCTGGTAAAAAATATGCCGTGGGATAATGTTAAGGATTGTACAGAGATCATCCGTTGTTATATACCGGATGAGCAAAAAACCATCAGAGAGATTTCGGCCATCATTGGACTTTGTGCATATGCTGCTACTTACTGGGGAGGTGAAGACCATCCCACTAGTAACAGTCTGAACGCATTGTTTGTGATGCTTGAGATGCTCAATTACATGGATTATACCATCATATTCTGGCGTATGAATTGATGAGTTACAGCTTGACATTTCTTCTTTCCTCCCTCTTCTTCTACCTTTCCCAGAAACAAACTTTTTTTACCCACTATAAAATAAAATGAGTATACTACCTGTTATATTTCTTCCTATATTTTTTTATTCTCCATTCGTTCAGACTTTTAACGTGCCTGAATGTATCGACAAAGGGCAATATTTTGCATCATTCATGGAGTTAGAAAACGAGCCAGTAATCTTACCATGTCCTCAAATAAATACGCTATCATCCGGATATAATATATTAGATATTTTATGGGAAAAACGAGGAGCGGATAATGATAGAATTATACAGATAGATAATGGTAGCAATATGCTAATTCTGAACCCGACACAATCAGACTCTGGTATTTATATATACATTACCACGAACGAAACCTACTGTGACATGATGTCGTTAAATTTGACAATCGTGTCTGTCTCAGAATCAAATATAGATCTTATCTCGTATCCACAAATAGTAAATGAGAGATCTACTGGTAAAATGGTATGTCCCAATATTAATGCATTTATTTCTAGTAACGTAAACACAGAATTATATGGAGCGGACATCGACGCCTTAGAAATAAGAGACTTAAACAACGGACACCTGGAATTATTACCATAGAAGATGTTAGAAAAAATGATGCTGGTTATTATACATGTGTTTTAGAATATATATATANNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTATATATATATATATATATGGGCAAAACATATAACGTAACCAGAATTATAAAATTAGAGGTACGGGATAGAATAATACCTCCTACTATGAAATTACCAGAAGGAGTAGTAACTTCAATAGGTAGTAATTTGACTATTGCATGTAGAGTATCGTTGAGACTTCCCACAACGGACACCGACGTCTTTTGGATAAGTAATGGTATATGTATTACGAAGAAGAAGACGAGGACGGAGACGGTAGAATAAGTGTAGCAAATAAAATCTATATGACCGATAAGAGACGTGTTATTACATCCTGGTTAAACATTAATCCTGTCAAGGAAGAAGATGCTACAACGTTTACGTGTATGGCGTTTACTATTCCTAGCATCAGCAAAACAGTTACTGTTAGTAAACGTGAATGTATGTTGTTACATTTCCATATCAATTGAGTTTATAAGAATTTTTTATACATTATCTTCCAACAAACAATTGACGAACGTATTGCTATGATTAACTCCCACAATACTATATATATTATTAATCATTAACTTGCAGACTATACCTAGTAGTGCTATTTTGACATACTCATGTTCTTGTGTAATCGCAGTATCTATATTATTAAAGTACGTAAATCTAGCTATAGTTTTATTATTTAATTTTAGATAATATACTGTCTCCGTATTTTTAAAAAATTACCACATCCTTTATTAAATCATGAATGGGAATTTCTGTGTCATCGTTAGTATATTGTGAACAACAAGAGCAGATATCTATAGGAAAGGGTGGAATGCGATACATTGATCTATGTAGTTTTAAAACATACGCGAACTTTGAAGAATTTATATAAATCATCTCACGAGATATTGCTCTCTGTCATATTCATACACCTGTATAAACTTTCTAGACATCTTACAATGTGTTATTTTATGATCATATTTACATATTTACTGGTATATCAAAGATGTTAGATTAGTTAATGGGAATCGTCTATAATAATGAATATTAAACAATTATAGGAGGAGTTTATACCTACAAAAACATCATAAAAATGAGTCATCGTCCGATTTATGTTTTAAATATACTAACATTACTACCTTCAGAAATTATATACGAAATATTATACATGCTGACAATTAACGATCTTTATAATATATAGTATCCACCTACCAAAGTATAATTGTATTTTTCTCATGTGATGTGTGTAAAAAACTGATATTATATAATTATCTTAGTACCTATGATGAAGATGAAGATGAAGATGAAGATGATGGTCCGTATATATTTTGTATCATTATCGTTATTGCTATTCCATAGTTACGCCATAGACATCGAAAATGAAATCACCGAATTCTTCAATAAAATGAGAGATACTCTACCAGCTAAAGACTCTAAATGGTTGAATCCAGTATGTATGTTTGGAGGCACAATGAATGATATGGCCGCTCTAGGAGAGCCATTCAGTGCAAAGTGTCCTCCTATTGAAGACAGTCTTTTATCGCATAGATATAAAGACTATGTGGTTAAATGGGAAAGGCTAGAAAAGAATAGACGGCGACAGGTTTCTAATAAACGTGTTAAACATGGTGATTTATGGATAGCCAACTATACATCTAAATTCAGTAACCGTAGGTATTTATGTACCGTAACCACAAAGAATGGTGACTGTGTTCAGGGTGTAGTTAGATCTCATGTGTGGAAACCTTCTTCATGCATTCCAAAAACATATGAACTAGGTACTTATGATAAGTATGGCATAGACTTATACTGTGGAATTCTTTATGCGAACCATTATAATAATATAACTTGGTATAAAGATAATAAGGAAATTAATATCGACGATTTTAAGTATTCACAAGCGGGAAAGGAATTAATTATTCATAATCCAGAGTTAGAAGATAGTGGAAGATACGACTGTTACGTTCATTACGACGACGTTAGAATCAAGAATGATATCGTAGTATCAAGATGTAAAATACTTACGGTTATACCGTCACAAGACCACAGGTTTAAACTAATACTAGATCCGAAAATCAACGTAACGATAGGAGAACCTGCCAATATAACATGCAGTGCTGTGTCAACGTCATTATTTGTCGACGATGTACTGATTGAATGGGAAAATCCATCCGGATGGATTATAGGATTAGATTTTGGTGTATACTCTATTTTAACTAGTAGAGGCGGTATCACCGAGGCGACTTTGTATTTTGAAAATGTTACTGAAGAATATATAGGCAATACATATACATGTCGTGGACACAACTATTATTTTGATAAAACTCTTACAACTACAGTAGTATTGGAGTAAATACACAATGCATTTTTATATACATTACTGAATTATTATTATTAATTATATCGTATTTGTGCTATAGAATGGATGAAGATACGCGACTATCTAGGTATTTGTATCTCACCGATAGAGAACATATAAATGTAGACTCTATTAAACAGTTGTGTAAAATATCAGATCCTAATGCATGTTATAGATGTGGATGTACGGCTTTACATGAGTACTTTTATAATTATAGATCAGTCAACGGAAAATACAAGTATAGATACAACGGTTACTATCAATATTATTCATCTAGCGATTATGAAAATTATAATGAATATTATTATGATGATTATGATAGAACTGGTATGAACAGTGAGAGTGATAATATATCAATCAAAACAGAATACGAGAATGAATATGAATTCTATGATGAAACACAAGATCAAAGTACACAACTAGTAGATTACGACATTAAACTCAAAACCAATGAGGATGATTTTGTTGATGAATTCTATGGTTATGATAGATCAGTGGGTGTCCATGATTATATAGATGTATCAATTAATAAAGTAGTATATGGAAGAGAGTCTCACGTAAGATGGTGGGATATATGGCAAGAACATAATGATGGCGTATACAGTATAGGAAAGGAGTGCATAGATAATATATACGAAGACAGACATACCGTAGACGAATTCTACAAGATAGACAGCGTATCAGATGTAGATGACGCAGAACATATATCTCAGATAACTAATGATGTATCTACACAAACATGGGAAAAGAAATCAGAGTTAGATAGATACATGGAAATGTATCCTCGTCATAGATATGGTAAGCATTCTGTCTTTAAGGGATTTTCTGACAAAGTTAGAAAAAATGATTTAGACATGAACGTGGTAAAAGAATTACTTTCTAACGGTGCATCTCTAACAATCAAGGATAGCAGTAATAAGGATCCAATTGCTGTTTATTTTAGAAGAACAATAATGAATTTAGAAATGATTGATATCATTAACAAACATACAACTATCTATGAACGCAGGTATATAGTACACTCCTATCTAAAAAATTATAGAAATTTCGATTATCCATTTTTCAGAAAGTTAGTTTTGACTAATAAACATTGTCTCAACAATTATTGTAATATAAGCGACGGCAAATATGGAACACCACTACATATATTAGCATCTAATAAAAAAATAATAACTCCTAATTACATGAAGTTATTAGTGTATAACGGAAATGATATAAACGCACGAGGTGAAGATACACAAATGCGAACTCCATTACACAAATATTTGTGTAAATTTGTATATCATAATATTGAATATGGTATCCGATACTATAATGAAAAGATTATAGACGCATTTATAGAGTTAGGAGCCGATCTAACTATTCCAAATGACGATGGAATGATACCAGTAGTTTACTGTATACACTCAAATGCCGAATATGGTTATAACAATATTACTAACATAAAGATAATACGTAAACTACTTAATCTTAGTAGACATGCGTCACATAATCTATTTAGAGATCGAGTCATGCACGATTATATAAGTAATACATATATTGATCTTGAGTGTTTAGATATCATTAGATCACTTGATGGGTACGATATTAATTGTTACTTTGAAGGACGTACACCACTTCATTGCGCTATACAATATAACTTCACTCAGATTGCTGAGTACTTATTAGATCGAGGAGCTGATATATCATTAAAGACAGACGATGGTAAAACTGTATTTGATTTATCGTTATGTAGTTACATTCCTCTTAAATGGACTAGCTTTTTGATTAGTCGTCTACCGCCTAAAAGTGTCATATGCTCACTGACTAACCATATAATAGATTATGTTCTTACGAACAATAGACGTATTATTTGGCAGAGTCAAATGATTAATAAGTACGTACTGTTACTGGACCCATCCTTTTATTATAGATTCAGAAATGTTATCGAAAACAAATTAGACCAATACAATAATCGTTATAATATGTTCGAACACGATAGGGACGTTAATGAAAAGTATGGCAAAGTCTTACATGACCTCGATACATATATCAAGGATGTACAAGTATTAAAATCTACTTCCATCACTAATAATATAACACTATACGACACTATTATAAATAATAAGTCAGAGTTTCCTATACGTCGTGTAAACGACAAACAATTAATTAATCTCATAAAATCCAATACATATCATAATCTTATCGAAAAAGTTATTAAAAATACATTAGAGAAATATACTTTAACTAATATAGTCCTCGAGTATATGATCTCATCTCGATCTCAATCATCTTATTTGAGTCGTATTCCTAATGAGATATTACTCGAAATATTATATAAACTCGACATGTACGATTTACGTAATCTATATACAAGATATATGAGAGAGAATGATATCACAGAGTATCATATAGAGAATACGAGGTCTGTTTCTACACAGACATGAATAATGAATACACATACAACGTTTTTTTTAATCTTAGATATAACACTAATTACATCAAGATTATATATTGAAATCGTAATTTGAGTTGTCTGATCATCATGGATATCGAAAATAATATACGTAACATTAGCAATCTTTTAGATGATTGATATATTATTATGCGATGTAATCATAACTATCGGAGATGTAGAAATTAAAGCGCATAAAACTATTTTGGTTGCCGGATCTACGTATTTTAAAACAATGTTCACAACATCTATGATAGCGAGAGATCTAGCAACTAGAGTAAATATACAGATGTTCGATAAAGATGCCGTCAAAAATATTGTACAGTACTTATACAATAGGTATATAAGTTCTATGAATGTGATAGACATATTAAAATGCACCGACTAAGAACGTAAAACGAACTATAGAATGTTATACAATGGGTGATGATAAGTAGAAGATGTTACCCGATATACCCATAGCATTATCTAGTTATGGCATGTGTGTATTAGATCAATACATATACATTATAAGCGGTCGTACCCAACACTGATTATACATCGGTACATACAGTAAATAGCATAGATATGGAGGAGGATACAAATATTTCAAATAAAGTTATGAGATACGCGCTGTCAATAATATATGGAAGACATTACCTAACTTCTGAACTGGAACTATAAATCCAGGCTCTCGCATAAAGATGAATATATATGTTGTATGCGACATCAAAGATGAAAAAATGTTAAGACTTATATATTTAGATATAACACGAATATGTATGACGGATGGGAATTGGTAACGATGACAGAAAGCAGATTGTCAGCTCTGCATACTATTCTTCATGACAATACCATAATGATGTTACATTGTTATGAAGCGTATATGTTACAAGATACATTTAATGTGCTTACGGAACATATATTTAGAAACATCTACTAACGATTTTTTATGCTTGTATTATTAATGGTATGTAATATGATTTAATTGATTGTGTACACGATACCAATTTGTCGAGTATGAATACGGAGTACAAACATAAACTGAAGTTTAACATTATTTATTTATGATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATACATTATATATCGTTATTGTTTGGTCTATGCCATGGATATCTTTAAAGAACTAATCTTAAAACATACGGATGAAAATGTTTTGATTTCTCCAGTTTCCATTTTATCTACTTTATCTATTCTGAATCATGGAGCAGCTGGTTCTACAGCTGAACAACTATCAAAATATATAGAGAATATGAATGAGAATACACCCGATGATAAGAAGGATGACAATAATGACATGGACGTAGATATTCCGTATTGCGCGACACTAGCTACCGCAAATAAAATATACGGTAGTGATAGTATCGAGTTCCATGCCTCATTCCTACAAAAAATAAAAGACGATTTTCAAACTGTAAACTTTAATAATGCGAACCAAACAAAGGAACTAATCAACGAATGGGTTAAGACAATGACAAATGGTAAAATTAATTCCTTATTGACTAGTCCGCTATCCATTAATACTCGTATGATAGTTATTAGCGCCGTCCATTTTAAAGCAATGTGGAAATATCCATTTTCTAAACATCTTACATATACAGACAAGTTTTATATTTCTAAGAATATAGTTACCAGTGTTGATATGATGGTGGGTACCGAGAATGACTTGCAATATGTACATATTAATGAATTATTCGGAGGATTCTCTATTATCGATATTCCATACGAGGGAAACTCTAGTATGGTGATTATACTGCCGGACGACATAGAAGGTATATATAACATAGAAAAAAATATAACAGATGAAAAATTTAAAAAATGGTGTGGTATGTTATCTACTAAAAGTATAGACTTGTATATGCCAAAGTTTAAAGTGGAAATGACGGAACCGTATAATCTGGTACCGATTCTAGAAAATTTAGGACTTACTAATATATTTGGATATTATGCAGATTTTAGTAAGATGTGTAATGAAACTATCACTGTAGAAAAATTTCTACATACGACGTTTATAGATGTTAATGAGGAGTATACAGAAGTATCGGCCGTTACAGGAGTATTCATGACTAACTTTTCGATGGTATATCGTATGAAGGTCTACATAAACCATCCATTCATATACATGATTAAAGATAACACCGGACATACACTTTTTATAGGGAAATACTGCTATCCGCAATAAATATAAACAATAGACTTTTATCACGTTATCTCATGTATAAAATATTACAAATAGTATAGCATAAACTAAAGTCGATACATACATTAAAACTTAAATAATAATGTAATTTACAATTAATAGTATAAACTAAAAAAATTAAAAAATTAAAAACAATATCATTATTATAAGTAATATCAAAATGACGATATACGGATTAATAGCGTATCTTATATTCGTGACTTCATCCATCGCTAGTCCACTTTACATTCCCGTTATTCCGCCCATTTCGGAAGATAAATCGTTCAATAGTGTAGAGGTATTAGTTTCTTTGTTTCCCGATGACCAAAAAGACTATACAGTAACTTCTCAGTTCAATAACTACACTATCGGTACCAAAGACTGGACTATCAACGTACTATCCACACCTGATGGTCTGGACATACCATTGACTAATATAACTTATTGGTCACGGTTTACTATAGGTCGTGCATTGTTCAAATCAGAGTCTGAGGATATTTTCCAAAAGAAAATGAGTATTCTAGGTGTTTCTATAGAATGTAAGAAGCCGTCGACATTACTTACTTTTTTAACCGTGCGTAAAATGACTCGAGTATTTAATAGATTTCCAGATATGGCTTATTATCGAGGAGACTGTCTAGAAGCCGTTTATGTAACAATGACTTATAAAAATACTAAAACTGGAGAGACTGATTACACGTACCTCTCTAATGGGGGGTTGCCTGCATACTATCGTAATGGGGTCGATGGTTGATTATTGATTAGTATATTCCTTATATTCCTTATTCTTTTTATTCACACAAAAAGAACATTTTTATAAACATGAAACCACTGTCTAAATGTAATTATGATCTTGATTTATAGATGATGATCAGCCTTCAGAGGATTTTGACCAGTATGTTTAATATGAAAAAAAACATAACTATTAAGCGCTATTGCGCTATTGTGCTTAATTATTTTGCTCTATAAACTGAATATATAGCCACAATTATTGACGGGCTTGTTTGTGACCGACAATCATGAATTTTCAGAAATTATCTCTGGCTATATATCTTACGGTGACATGTTCGTGGTGTTATGAAACATGTATGAGAAAAACTGCGTTGTATCATGACATTCAATTGGAGCATGTAGAAGACAATAAAGATAGTGTAGCATCGCTACCGTACAAGTATCTACAAGTAGTCAAACAAAGAGAACGTAGTAGATTGTTGGCTACATTTAATTGGACGGATATAGCTGAGGGTGTTAGAAATGAGTTCATTAAAATATGTGATATCAACGGAACATATCTATATAATTATACTATTGCTGTTAGTATAATTATTGATTCCACGGAAGAACTACCAACAGTTACTCCAATTACAACATATGAACCTTCTATATATAATTATACTATCGATTATAGCACTGTTATTACTACTGAAGAACTACAAGTGACTCCAACATATGCACCTGTAACAACTCCTCTTCCAACATCAGCAGTTCCTTATGATCAACGATCGAATAACAATGTAAGTACTATATCTATTCAGGTACTGAGTAAAATATTGGGAGTCAATGAAACAGAATTAACTAATTATCTTATTATGCATAAAAATGACACTGTTGACAATAACACCATGGTTGATGATGAGACATCTAACAATAACACATTACATGGTAATATAGGATTTTTGGAAATAAATAATTGTTATAATGTTTCTGTGTCAGATGCTAGTTTTAGAATAACATTAGTAAACGATACTTCTGAAGAAATTTTGCTAATGCTAACAGGAACTAGTTCATCCGACACCTTCATATCTTCCACCAATATCACTGAATGTTTGAAAACATTAATCAATAATGTGTCGATTAATGATGTACTTATAACACAAAATATGAATGTAACATCTAATTGTGATAAATGCTCAATGAATTTGATGGCATCCGTTATTCCTGCAGTTAATGAATTTAACAATACGTTGATGAAAATTGGTGTAAAAGATGATGAAAACAATACGGTATATAAATATTATAATTGTAAACTAACTACAAATTCTACATGTGATGAGTTAATCAATTTAGATGAAGTCATTAACAACATAACTCTGACAAATATTATACACAATAGTGTTTCGACAACTAACAGCAGAAAAAGACGAGATCTGAATGATGAGTTTGAATTTTCCACTTCCAAGGAATTAGATTGTCTTTACGAATCATATGGTGTAAACGATGATATAAGTCATTGTTTTGCATCACCTAGACGTAGACGATCTGACGACAAAAAGGAGTACATGGACATGAAATTATTCGACCACGCGAAAAAAGATTTAGGAATAGACAGTGTTATTCCTAGAGGTACAACCCATTTCCAAGTAGGTGCATCTGGTGCAAGTGGTGGTGTTGTAGGAGATAGTTTCCCATTTCAAAATGTTAAATCGCGTGCCAGTCTATTGGCGGAAAAAATAATGCCTAGAGTACCTATTACTGCTACCGAAGCTGATCTATATGCAACTGTAAATAGACAACCCAAGTTACCAGCAGGTGTTAAAAGTACTCCGTTTACAGAGGCGCTTGTGTCTACGATAAACCAAAAGCTTTCTAATGTTAGAGAGGTAACTTATGCTTCGCTCAATCTGCCAGGATCAAGTGGCTATGTTCATAGACCATCTGATTCTGTTATTTATAGCAGTATAAGACGGTCACGTTTACCTAGTGATAGCGATAGTGATTATGAGGATATACAAACTGTTGTTAAGGAATATAATGAAAGATATGGTAGATCAGTCAGTAGAACACAGTCATCAAGTAGTGAAAGCGATTTTGAAGATATAGATACTGTTGTTAGGGAATATAGACAAAAATATGGCAATGCAATGGCAAAAGGACGTAGTAGTTCCCCTAAACCTGATCCATTATATAGTACTGTTAAGAAAACAACTAAAAGTCTATCTACTGGTGTAGACATAGTTACAAAACAATCAGACTATTCTCTATTACCTGACGTTAATACTGGCAGTTCTATTGTGTCACCTCTCACCAGAAAAGGAGCTACTAGACGACGACCTAGACGCCCTACAAATGATGGTCTACAGAGTCCAAATCCTCCTCTCCGTAATCCACTTCCTCAACATGATGATTATTCTCCTCCACAAGTACACAGACCTCCACCACTTCCTCCTAAACCAGTCCAAAATTCGCCACAACTTCCCCCTAGACCAGTAGGTCAATTACTACCTCCTCCTATAGATCAACCAGATAAAGGATTTAGTAAGTTTGTATCACCTAGACGGTGTAGAAGAGCAAGCTCTGGAGTCATATGTGGTATGATACAATCAAAACCAAACGATGATACCTATTCACTTCTTCAACGATCAAAAATTGAACCAGAATATGTGGAGGTTGGTAATGGTATACCCAAGAACAATGTTCCTGTAATAGGTAATAAACATAGTAAAAAATATACATCGACGATGTCAAAAATATCAACAAAATTTGATAAATCTACGGCATTTGGAGCAGCAATGTTACTAACTGGTCAGCAGGCCATTAGCCAACAGACTAGATCAACTACGTTGAGTAGAAAAGATCAGATGAGTAAGGAAGAAAAGATATTCGAAGCAGTTACAATGAGTCTATCAACTATAGGTTCAACGTTGACGTCTGCAGGTATGACGGGTGGTCCAAAACTAATGATTGCAGGAATGGCTATAACGGCTATAACTGGTATAATAGATACGATAAAAGATATATATTACATGTTTTCAGGACAGGAGAGGCCAGTAGATCCTGTTATTAAATTATTTAATAAGTACACTGGCTTAATGTCCGATAATAATAAAATGGGTGTAAGAAAATGTTTGACACCCGGTGACGACACACTTATTTATATCGCATACAGAAACGATACCAGTTTTAAACAGAATACGGATGCGATGGCTTTGTATTTCTTAGATGTTATCGATTCAGAGATCCTATATCTAAACACATCAAATTTAGTTCTAGAGTATCAACTAAAGGTGGCTTGCCCCATAGGAACATTAAGATCTGTAGATGTGGACATAACTGCGTATACAATATTATATGATACAGCGGATAATATTAAGAAATACAAGTTTATCAGAATGGCAACGCTACTATCCAAACATCCAGTTATTAGATTGACATGTGGTTTAGCAGCAACATTGGTGATTAAACCGTACGAGGTACCCATCAGTGATATGCAACTACTAAAAATGGCGACGCCTGGTGAACCAGAATCCACTAAATCTATACCATCCGATGTCTGTGATAGGTATCCTCTAAAGAAATTCTATCTTTTAGCTGGTGGTTGTCCCTATGATACATCTCAAACTTTTATTGTACATACTACTTGCAGTATTCTACTAAGAACAGCTACACGGGATCAGTTTAGAAACAGATGGGTGTTACAAAATCCATTTAGACAAGAAGGGACATATAAGCAACTGTTTACCTTTAGCAAATACGATTTTAACGACACCATAATCGATCCTAATGGTGTGGTGGGTCATGCTAGCTTTTGTACCAATAGAAGCAGCAACCAATGTTTCTGGTCCGAACCTATGATATTGGAAGATGTATCATCGTGTAGTTCTAGAACTAGAAAAATATACGTAAAACTGGGAATATTTAATGCTGAAGGTTTTAATAGTTTTGTACTAAATTGTCCAACTGGGTCTACACCTACATACATCAAACATAAAAATGCGGACAGTAACAATGTTATCATAGAGCTACCTGTAGGTGATTACGGCACAGCCAAATTGTATTCAGCAACAAAACCATCGAGGATAGCTGTGTTCTGCACACATAACTATGATAAACGATTCAAATCAGATATTATAGTTCTAATGTTTAATAAAAACAGCGGTATTCCATTTTGGAGCATGTACACAGGAAGTGTAACTAGTAAAAATAGAATGTTTGCCACATTGGCTAGAGGAATGCCGTTTAGATCAACGTATTGCGATAACAGACGACGATCAGGTTGTTATTATGCAGGAATACCATTTCATGAAGATAGTGTAGAAACAGATATACATTATGGACCAGAAATAATGTTAAAGGAAACATATGACATAAACAGTATTGACCCACGAGTTATAACAAAGTCAAAGACCCATTTTCCTGCTCCATTGAGTGTAAAATTCATGGTTGACAATTTAGGAAATGGATATGACAACCCTAATTCATTTTGGGAAGATGCTAAAACTAAGAAACGGACATATAGTGCAATGACGATAAAAGTCCTACCATGTACAGTGAGAAATAAAAATATAGACTTTGGATATAACTATGGAGATATTATTTCTAATATGGTTTATCTACAATCTACTAGTCAGGATTATGGAGATGGTACCAAATATACATTTAAATCCGTAACTAGATCAGATCATGAGTGTGAATCTAGCTTAGATCTAACGTCTAAGGAAGTAACTGTGACATGTCCTGCGTTTAGTATACCAAGAAATATATCAACATATGAAGGTCTATGCTTTAGTGTTACTACATCTAAAGATCATTGTGCTACAGGTATTGGTTGGTTAAAATCTAGTGGTTATGGGAAGGAAGATGCTGATAAACCACGTGCTTGTTTTCATCATTGGAATTATTACACACTGTCGTTGGATTATTACTGTTCATACGAAGATATTTGGAGAAGCACCTGGCCTGACTATGATCCATGTAAGTCATATATCCATATAGAGTATAGAGATACATGGATAGAATCTAATGTGTTACAGCAACCTCCTTACACATTCGAATTCATTCATGACAATTCTAACGAATATGTGGATAAAGAAATTAGTAACAAATTAAATGATCTGTACAATGAATACAAGAAGATTATGGAATATAGCGACGGATCATTGCCGGCGTCTATAAACAGATTAGCAAAGGCATTGACTTCAGAGGGTAGAGAAATAGCAAGTGTTAATATAGATGGTAATCTGTTAGATATCGCATATCAAGCAGATAAGGAAAAGATGGCCGACATACAGACAAGAATAAATGATATTATTAGAGATTTGTTTATACACACTCTATCAGACAAAGATATAAAAGACATTATAGAATCCGAAGAAGGTAAGAGATGTTGTATAATAGATGTTAAGAACAATCTTGTTAAAAAGTACTATTCTATTGATAATTATCTATGTGATACTTTAGATGATTATATATACACCTCTGTAGAATATAACAAATCCTATGTGTTAGTAAACGATACTTATATAAGCTATGACTATCTTGAATCATCAGGTGTAGTTGTTCTATCATGTTATGAAATGACTATAATCTCCTTGGATACAAAAGACGCCAAAGATGCTATAGAAGATGTGATAGTAGCAAGTGCGGTAGCCGAAGCATTGAATGACATGTTTAAGGAATTTGATAAAAACGTAAGTGCTATTATAATAAAAGAAGAAGATAATTATCTAAACAGTTCGCCCGATATCTACCATATAATATATATCATAGGTGGCACTATTCTGCTACTGTTAGTCATTATTTTAATATTGGCAATTTATATAGCGCGCAATAAATACAGAACCAGGAAATATGAAATAATGAAATATGACAATATGAGCATTAAATCTGAGCATCATGATAGTCTTGAAACAGTGTCTATGGAAATTATTGATAATCGGTACTAATAAAATAGTTTAACTCTTTTAGAACCAGTTTGGTACTGTAATTTCAGTTCATTACTCGTTGAGAATATTGATGATTTTTTTTAAATGAGTATCGGTAGTTACATATTACCATATCATCCATTATATAATCGATGATGCATGTATTAGAATACTTTCCGAATAAGTCTTCTAAATATTGTATTAATTATGAAAAACTATGCTATGTGAGTATGATTCAAAGATGTTTAATGATACGATACTAGATTTTATCTCTAGCGAGATTGTTTAGAATCATTTATCATAACTATGTTTAATAAATTCATCAACGAATATCGATAAAGACCTCTTGTAATTCGAGTATAGGAAGTAGTATTACCATATCAACTTCCGAGTTAACAATTACTCTAAAACATGAGGATTGTACTCCTGTCTTTATTGGAGATCACTATTTAGTCGTTGATAAACTAGTAACCTCAGGTTTCTTTACAAACGATAAAGTACAACATCAAGACCTCACAACACAGTGCAAGATTAATCTAGAAATCAAATGTAATTCTGGAGGAGAATCTAGACAACTAACACCCACGGCGAAGTATACTTTATGCCTCATTCAGAAACGGTAACTGTAGTAGGAGACTGTCTCTCTAATCTCGATGTATATATAATATATACCAATACGGACGCGATATATTCCGACATGAATGGCGTCGCTTATCATATGTTATATCCTAAATGTTGATCATATTCCACAAATGATTGTGAACGAGATTAAATCATCTAACAAATAATTAGTTTTTTATGACATTAACATATAATAAATAAATTAATCATTATTGACTTAACGATGACGAAAGTTATCATTATCTTAGGATTCTTGATTATTAATACAAATTCGTTGTGTCTATGAAATGTGAACAAGGTGTCTCATATTATAATGCACAAGAATTAAAGTGTTGTAAACTATCTAGCCAGGAACATATTCAGATTATCGATGTGATAAATACAGCGATACCATCTGTGGACATTGTCCAAGTGACACATTCACGTCAATATATAATCGTTCTCCTCGGTGTCATAGTTGTAGAGGTCACACCTTGTACACCTACCACAAATAGAATATGTCATTGTGACTCGAATAGTTATCGTCTCCTTAAAGCTTCTGATGGTAACTGTGTTACATGTGCTCCTAAAACAAAATATGGTCGTGTGTACGGAAAGAAAGGAGAAAATGATATGGAATACCATTTGTAAGAAATGTCGGAAGGGTACTTATTCAGATATTGTATCTGACTCTGATCAATGTAAACCTATGACAAGATAAGACTTACTCGCATCTACTGGATAGACATAAATATCCTCCTCGTAATAATGAAATATAATATACACTAATTATTAATATCAATCGAGTATTAACATATAAGTTATTTTTAAACCCCTTTTGGGTTCCGTCCTAAACGGCGTTTCGGTCTGTGTCGCCACCATGGTCACACCGAGCCTCTGCGTGCTCCTCCATCGAGGACGACTTCAACTATGACAGCTCGGTGGCGTCTGCCAGCGTGTACATACGAATGGCATTTCTAAGAAAAGTCTACGGTATCCTTTCTACAATTTCCTTTAACAACGGCAACAGCTGCAGTATTTTTATACTTTGAATGCATCGGACATTTATACAAGGGAGTCCTGTTCTAATATTGGCATCAATGTTCGGATCTATAGGCTTGATTTTCGCATTGACTTTACACAGACATGAACATCCCCTGAATCTGTACATACTTTGTGGATTTACACTGTTAGAATCTCTAACGCTGGCCTCTGTTGTTACTTTCTATGATGCACGTATCGTTATGCAAGCTTTCATGTTGACTACTGCAGTGTTTCTTGCTCTGACTACATATACTCTACAATCAAAGAGAGATTTCAGTAAACTTGTAACAGGATTGTTTGCTGCTTTCTGGATTTTAATTTTGTCAGGAGTCTTGAGGATAAAGTTTAAAATAGAATTAATAAAGAACATATAGGTCATTTTTTAAACATGGATAGAAACCAAGGTTGTTAGTTAATAATATACAAGATATTTTTTCTCACTCTGATCCATGTAAACCAAGGACGAGAGACACTCTCATTCCTCATTCACGACACCATTAAAAATGGAAATTAAAGCCCTCTATTAAGCACAGACGGCTACAGGTCTACCATCAGGTTACCTTCGTCTACCTTCACAATGGCCTCTCCTTGTGCCCAGTTCAGTCCCTGTCATTGCCACGCTACTAAGGACTCCCTGAATACCGTGACTGACGTCAGACATTGTCTGACTGAATACATCCTGTGGGTTTCTCATAGATGGACCCATAGAGAAAGCGCAGGGCCTCTCTACAGGCTTCTCATCTCTTTCAGAATTGATGCAATGGAGCTATTTGGTAGCGAGTTGAAGGAGTTCTCGAATTCACTTCCGTGGGACAATATCGACAATTGCGTGGAGATCATTAAATGTTTCATCAGAAATGACTCCATGAAAACCGCCAAAGAACTTTGTGCAATAATTGGACTTTGTACTCAATCAGCTATTGTCACTGGAAGAGTCTTCAATGATAAGTATATCGACATACTACTTATGCTGCGAAAGATTCTGAACGAGAACGACTATCTCACCCTCTTGGATCATATCCTCACTGCTAAATACTAAATCTCCTTCATGCTCTCTCACTAATACTCTTACTCACTACACTTTTTATCATCTTATGATGAATGATTGCCTTCATCATTTTTTCGTGGAATATAATATAGGAATAATTAGCACCAGAATAGCTATGGATATCTCGTTAAGAATATTCTCTATAAGAGACATAATGTAGACATAGTTATTATATCCTTCTTAGATAAGTGTTACGCTACTGGAAAGTTTCCATCGTTATTATTACATGAAGATGATATAATTAAACCAACATTGAGATTGGCTCTTATGTTAGCTGGATTGAATTACTGTAATAAATGCATCGAGTATAGAGGGATATAGCAATTCTCGATAATAGTCATGCAATATTTGAATGAGACTGATAATTTAGGTAATACAGTACTACACACATATCTTTCTAGATTATATATCGTTAAAAATCTGTAAGATGTATATTTCTCATAAGTATCCACTGTGTAATATTATTAATGGATATATAGATAACGCAATAGGGACTAATAGTATTGTAAAAGATATAATCGACTATTTACGTACATATCCAGATATCTATATTCCTACTAGTTTGCTGCGTAGTTGCATCATTGATATGCATGATTTATCAGGATTCAGAGATGAATTACTAAGTAAACTACAATCCCACAATAAGTAAGAATCAAATATCAAAAACTCACTTTTGATTTTTCTAGTCTTAAGTAATACATATATTTATTAATAGACCTATGAAATAAAAAAAGGTAACAATGGATTCGCGTATAGCTATTTACGTATTAGTATCGGCATCTCTTTTGTATCTTGTTAATTGTCACAAACTAGTACATTACTTCAATCTGAAAATAAATGGAAGTGATATAACTAATACAGCAGATATATTGCTGGACAATTATCCAATTATGACCTTTGATGGAAAGGATATTTATCCATCTATCTCGTTCATGGTCGGTAATAAACTTTTCCTAGATCTTTATAAAAATATCTTTGAAGAATTTTTCAGACTATTTCGAGTATCTGTAAGTAGTCAATACGAGGAATTAGAATATTATTATTCATGTGATTATACTAACAACCGTCCTACAATTAAACAACATTACTTTTATAACGGCGACGAATATACTGAAATTGATAGATCGAAAAAAGCCACTAATAAAAACAGTTGGTTAATTACTTCAGGCTTTAGACTACAAAAATGGTTCGATAGCGAAGATTGTATAATTTATCTCAGATCTTTAGTTAGAAGAATGGAAGACAGTAACAAAAACAGTAAAAAAACTTAGTACTTAGATATCGAAAAAATATATTTTTGTAGACTCTTGAGAATAGAAGGAAAACATGTACATAATTATAAAAAATGAAAATCAATGGCGAATAAGACAGTGCGATTCGCACCATGGAGTCGGTAGNNNNNNNNGCNNNNNNNNNNNNNTTTCACGACGACCTCGATCNNNNNNNNNTNNCTTTGGTAGATGATTATAAAAAACATGGATTAGGTGTTGACTGTTATGTTCTAGAACCAGTTGTTGACAGGAAAATATTTGATAGATTTCTCCTTGAACCAATTTGTGATCCTGTAGATGTTCTGTATGATTATTTTAGGATTCATAGAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTGTTTGCATATATTACATATAAAGATATTATATCTGCATTAGTGTCAAAGAATTATATGGAAGATATTTTCTCTATAATTATTAAGAATTGTAATTCTGTGCAAGATCTCTTACTTTACTATCTATCTAATGCATATGTAGAAATAGACATTGTTGATCTTATGGTAGATCATGGGGCTGTAATATATAAAATAGAATGCTTGAATGCCTATTTTAGGGGAATATGTAAAAAGGAAAGTAGTGTTGTTGAGTTTATTTTGAATTGTGGTATCCCAGATGAAAATGATGTTAAATTAGATCTATATAAAATAATTCAGTATACTAGGGGATTCCTTGTAGATGAACCCACAGTATTAGAAATTTATAAGCTTTGTATCCCATATATTGAAGATATCAATCAACTAGATGCTGGTGGAAGGACCTTGCTTTATCGCGCTATCTATGCAGGTTATATAGATTTAGTATCATGGCTATTAGAAAATGGAGCAAATGTCAACGCAGTAATGAGTAATGGATATACATGTCTTGACGTGGCCGTGGATAGGGGATCTGTCATCGCCCGTAGGGAAGCACATCTTAAAATATTAGAAATATTGCTTAGAGAACCATTGTCTATTGACTGTATAAAATTAGCTATACTTAATAATACAATTGAAAACCATGATGTGATAAAGCTCTGTATCAAGTATTTTATGATGGTAGATTATTCACTTTGTAATGTGTATGCATCATCACTCTTTGATTATATAATTGATTGTAAACAAGAATTGGAGTACATTAGGCAGATGAAAATTCATAATACAACCATGTATGAGTTAATCTATAATAGAGACAAAAACAAGCATGCTTCCCATATTCTACATAGGTATTCTAAACATCCAGTTTTGACACAGTGTATCACTAAAGGATTCAAGATTTACACAGAAGTAACCGAGCAGGTCACTAAAGCTCTAAACAGACGTGCTCTAATAGATGAGATAATAAACAATGTATCAACTGATGACAATCTCCTATCAAAACTTCCATTAGAAATTAGGGATCTAATTGTTTCACAAGCTGTCATATAGAGTTCTATCCACCCACCTTTCTTGAAATGAGTTAATAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTAAGTCATAAGTTAGTTTATAGTCTAACACTTCTAATTTTTATACCTTGATCTTTTTCTCTAATTATGAAAAAGTAAATCATTATGAAGATGGATGAAATGGACGAGATTGTGCGCATCGTTAACGATAGTATGTGGTACGTACCTAACGCATTTATGGACGACGGTGATAATGAAGGTCACATTTCTGTCAATAATGTCTGTCATATGTATCTCGCATTCTTTGATGTGGATATATCATCTCATCTGTTTAAATTAGTTATTAAACACTGCGATCTGAATAAACGACTAAAATGTGGTAACTCTCCATTACATTGCTATACGATGAATACACGATTTAATCCATCTGTATTAAAGATATTGTTACGCCACGGCATGCGTAACTTTGATAGCAAGGATAAAAAAGGACATATTCCTCTACACCACTATCTGATTCATTCACTATCAATCGATAACAAGATCTTTGATATACTAACGGACCCCATTGATGACTTTAGTAAATCATCCGATCTATTGCTGTGTTATCTTAGATATAAATTCAATGGGAGCTTAAACTATTACGTTCTGTACAAATTATTGACTAAAGGATCTGACCCTAATTGCGTCGATGAGGATGGACTCACTTCTCTTCATTACTACTGTAAACACATATCCGCGTTCCACGAAAGCAATTATTACAAGTCAAAGAGTCACACTAAGATGCGAGCTGAGAAGCGATTCATCTACGCGATAATAGATCATGGAGCAAACATTAACGCGGTTACGAAAATCGGAAATACGCCGTTACACACTTACCTTCAACAGTATACCAAACATAGTCCTCGTGTGGTGTATGCTCTTTTATCTCGAGGAGCCGATACGAGGATACGTAATAATCTTAATTGTACACCCATCATGGAATACATAAAGAACGATTGTGCAACAGGTCATATTCTCATAATGTTACTCAATTGGCACGAACAAAAATACGGGAAATTACAAAAGGAAGAAGGACAACATCTACTTTATCTATTCATAAAACATAATCAAGGATATGGAAGTCGCTCTCTCAATATACTACGGTATCTACTAGATAGATTCGACATTCAGAAAGACGAATACTATAATACAATGACTCCTCTTCATACCGCCTTCCAGAATTGCAATAACAATGTTGCCTCATACCTCGTATACATTGGATACGACATCAACCTTCCGACTAAAGACGATAAGACAGTATTCGACTTGGTGTTTGAAAACAGAAACATTATATACAAGGCGGATGTCGTTAATGACATTATCCACCACAGACTGAAAGTATCTCTACCTATGATTAAATCGTTGTTCTACAAGATGTCGGAGTTCTCTCCCTACGACGATCACTACGTAAAGAAGATAATAGCCTACTGCCTATTAAGGGACGAGTCATTTGCGGAACTACATACTAAATTCTGTTTAAACGAGGACTATAAAAGTGTATTTATGAAAAATATATCATTCGATAAGATAGATTCCATCATCGAAAAATGTAGTCGTGACATAAGTCTCCTCAAAGAGATTCGAATCTCAGACACCGACTTGTATACGGTATTGAGAACAGAAGACATTCGGTATCACACATATCTCGAAGCCATACATTCAGACAAACGCATTTCATTTCCCATGTACGACGATCTCATAGAACAGTGTCATCTATCGATGGAGCATAAAAGTAAACTCGTCGACAAAGCACTCAATAAATTAGAGTCTACCATCGATAGTCAATCTAGACTATCGTATTTGCCTCCGGAAATTATGCGCAATATCATAACCAAGCTAAGCGACTACCATCTAAACAGTATGTTGTACGGAAAGAACCATTACAAATATTATCCATGATAGAAAGAAAATATTTAAAAAATAATCTATATGATTGGAGAAGTAGGAAACAAACAGTAACAAGACGACGATTACTACATTATTAAATCATGAGGTCCGTATTATACTCGTATATATTGTTTCTCTCATGTATAATAATAAACGGAAGAGATATAGCACCACATGCACCATCCAATGGAAAGTGTAAAGACAACGAATACAGAAGCCGTAATCTATGTTGTCTATCGTGTCCTCCGGGAACTTACGCTTTCAGATTATGTGATAGCAAGACTAATACACAATGTACACCGTGTGGTTCGGATACCTTTACATCTCACAATAATCATTTACAGGCTTGTCTAAGTTGTAACGGAAGATGTGATAGTAATCAGGTAGAGACGCGATCGTGTAACACGACTCACAATAGAATCTGTGAATGCTCTCCAGGATATTATTGTCTTCTCAAAGGAGCATCAGGGTGTAGAACATGTATTTCTAAAACAAAGTGTGGAATAGGATACGGAGTATCCGGATACACGTCTACCGGAGACGTCATCTGTTCTCCGTGTGGTCCCGGAACATATTCTCACACCGTCTCTTCCACAGATAAATGCGAACCCGTCGTAACCAGCAATACATTTAACTATATCGATGTGGAAATTAACCTGTATCCAGTCAACGACACATCGTGTACTCGGACGACCACTACCGGTCTCAGCGAATCCATCTCAACGTCGGAACTAACTATTACCATGAATCATAAAGATTGTGATCCAGTCTTTCGTGCAGAATACTTCTCTGTCCTTAATAATGTAGCAACTTCAGGATTCTTTACAGGAGAAAATAGATATCAGAATACTTCAAAGATATGTACTCTGAATTTCGAGATTAAATGTAACAACAAAGATTCATCTTCCAAACAGTTAACGAAAACAAAGAATGATACTATCATGCCGCATTCAGAGACGGTAACTCTAGTGGGCGACTGTCTATCTAGCGTCGACATCTACATACTATATAGTAATACCAATACTCAAGACTACGAAAATGATACAATCTCTTATCATATGGGTAATGTTCTCGATGTCAATAGCCATATGCCCGCTAGTTGCGATATACATAAACTGATCACTAATTCCCAGAATCCCACCCACTTATAGTAAGTTTTTTTACCTATAAATAATAAATACAATAATTAATTTCTCGTAAAAGTAGAAAATATATTCTAATTTATTATATGGTAAGAAAGTAGAATCATCTAGAACAGTAATCAATCAATAGCAATCATGAAACAATATATTGTCCTGGCATGCATGTGCCTAGTGGCAGCTGCTATGCCTACTAGTCTTCAACAATCTTCATCCTCGTGTACTGAAGAAGAAAACAAACATCATATGGGAATCGATGTTATTATCAAAGTCACAAAGCAAGACCAAACACCGACCAATGATAAGATTTGTCAATCCGTAACGGAAGTTACAGAGACCGAAGATGATGAGGTATCCGAAGAAGTTGTAAAAGGAGATCCCACCACTTATTACACTATCGTCGGTGCGGGTCTTAACATGAACTTTGGATTCACCAAATGCCCAAAGATTTTATCCATCTCCGAATCCTCTGATGGAAACACTGTGAATACTAGATTGTCCAGCGTGTCACCGGGACAAGGTAAGGACTCTCCCGCGATCACGCGTGAAGAAGCTCTGGCTATGATCAAAGACTGTGAGATGTCTATCGACATCAGATGTAGCGAAGAAGAGAAAGACAGTGACATCAAGACCCATCCAGTACTTGGGTCTAACATCTCACATAAGAAAGTGAGTTACAAAGATATCATCGGTTCAACGATCGTTGATACAAAATGTGTCAAGAACCTAGAGTTTAGCGTACGTATCGGAGACATGTGTGAGGAATCATCTGAACTTGAAGTCAAGGATGGATTCAAGTATGTCGACGGATCGGCATCTGAAGGTGCAACCGATGATACTTCACTCATCGATTCAACAAAACTCAAAGCATGTGTCTGAATCGATAACTCTATTCATCTGAAAATGGATGAGTTGGGTTAATCGAACGATTCAGACACCGCACCACGAATTAAAAAAGACCGGGCACTATATTCCGGTTTGCAAAACAAAAATATTTAACTACATTCACAAAAAGTTACCTCTCGTTACTTCTTCTTTCTGTTTCAATATGTGATACGATATGATCACTATTCGTATTCTCTTGGTCTCATAAAAAAGTTTTACAAAAAAAAAAAAAATATTTTTATTCTCTTTCTCTCTTCGATGGTCTCACAAAAATATTAAACCTCTTTCTGATGTCTCAACTATTTCGTAAACGATAACGTCCAACAATATATTCTCGTAGAGCTTATCAACATCCTTATACCAATCTAGGTTGTCAGACAATTGCATCATAAAATAATGTTTATAATTTACACGTTAACATCATATAATAAACGTATATAGTTAATATTTTTGGAATATAAATGATCTGTAAAATCCATGTAGGGGACACTGCTCACGTTTTTTCTCTAGTACATAATTTCACACAAGTTTTTATACAGACAAATTAATTCTCGTCCATATATTTTAAAACATTGACTTTTGTACTAAGAAAAATATCTTGACTAACCATCTCTTTCTCTCTTCGATGGGTCTCACAAAAATATTAAACCTCTTTCTGATGGAGTCGTAAAAAGTTTTTATCCTTTCTCTCTTCGATAGGTCTCACAAAAATATTAAACCTCTTTCTGATGGTCTCTATAAACGATTGATTTTTCTTACCCTCTAGAGTTTCCTACGGTCGTGGGTCACACATTTTTTTCTAGACACTAAATAAAATAGTAAAATTAAATTAATTA diff --git a/data_output/nextstrain/mpox/lineage-b.1/unreleased/tree.json b/data_output/nextstrain/mpox/lineage-b.1/unreleased/tree.json new file mode 100644 index 00000000..574c8e8a --- /dev/null +++ b/data_output/nextstrain/mpox/lineage-b.1/unreleased/tree.json @@ -0,0 +1 @@ +{"version":"v2","meta":{"title":"Nextclade reference tree for Mpox virus (Lineage B.1)","updated":"2023-11-21","build_url":"https://github.com/nextstrain/mpox/nextclade","data_provenance":[{"name":"GenBank","url":"https://www.ncbi.nlm.nih.gov/genbank/"}],"maintainers":[{"name":"Cornelius Roemer","url":"https://neherlab.org"},{"name":"Richard Neher","url":"https://neherlab.org"},{"name":"Nextstrain team","url":"https://nextstrain.org"}],"display_defaults":{"color_by":"lineage","map_triplicate":false,"distance_measure":"div","tip_label":"strain_display","transmission_lines":false},"genome_annotations":{"OPG001":{"end":1575,"seqid":"resources/genome_annotation.gff3","start":835,"strand":"-","type":"gene"},"OPG001_dup":{"end":196375,"seqid":"resources/genome_annotation.gff3","start":195635,"strand":"+","type":"gene"},"OPG002":{"end":2751,"seqid":"resources/genome_annotation.gff3","start":1702,"strand":"-","type":"gene"},"OPG002_dup":{"end":195508,"seqid":"resources/genome_annotation.gff3","start":194459,"strand":"+","type":"gene"},"OPG003":{"end":4607,"seqid":"resources/genome_annotation.gff3","start":2841,"strand":"-","type":"gene"},"OPG003_dup":{"end":194369,"seqid":"resources/genome_annotation.gff3","start":192603,"strand":"+","type":"gene"},"OPG005":{"end":189660,"seqid":"resources/genome_annotation.gff3","start":189199,"strand":"+","type":"gene"},"OPG015":{"end":6156,"seqid":"resources/genome_annotation.gff3","start":4843,"strand":"-","type":"gene"},"OPG015_dup":{"end":192367,"seqid":"resources/genome_annotation.gff3","start":191054,"strand":"+","type":"gene"},"OPG016":{"end":190940,"seqid":"resources/genome_annotation.gff3","start":190410,"strand":"+","type":"gene"},"OPG019":{"end":8008,"seqid":"resources/genome_annotation.gff3","start":7580,"strand":"+","type":"gene"},"OPG021":{"end":10315,"seqid":"resources/genome_annotation.gff3","start":9587,"strand":"+","type":"gene"},"OPG022":{"end":10858,"seqid":"resources/genome_annotation.gff3","start":10478,"strand":"-","type":"gene"},"OPG023":{"end":12900,"seqid":"resources/genome_annotation.gff3","start":10918,"strand":"-","type":"gene"},"OPG024":{"end":13228,"seqid":"resources/genome_annotation.gff3","start":13034,"strand":"-","type":"gene"},"OPG025":{"end":15267,"seqid":"resources/genome_annotation.gff3","start":13375,"strand":"-","type":"gene"},"OPG027":{"end":16377,"seqid":"resources/genome_annotation.gff3","start":15925,"strand":"-","type":"gene"},"OPG029":{"end":17069,"seqid":"resources/genome_annotation.gff3","start":16602,"strand":"-","type":"gene"},"OPG030":{"end":17833,"seqid":"resources/genome_annotation.gff3","start":17213,"strand":"-","type":"gene"},"OPG031":{"end":18828,"seqid":"resources/genome_annotation.gff3","start":17878,"strand":"-","type":"gene"},"OPG034":{"end":20005,"seqid":"resources/genome_annotation.gff3","start":19361,"strand":"-","type":"gene"},"OPG035":{"end":20404,"seqid":"resources/genome_annotation.gff3","start":20051,"strand":"-","type":"gene"},"OPG036":{"end":21064,"seqid":"resources/genome_annotation.gff3","start":20531,"strand":"-","type":"gene"},"OPG037":{"end":22433,"seqid":"resources/genome_annotation.gff3","start":21105,"strand":"-","type":"gene"},"OPG038":{"end":23159,"seqid":"resources/genome_annotation.gff3","start":22497,"strand":"-","type":"gene"},"OPG039":{"end":24118,"seqid":"resources/genome_annotation.gff3","start":23264,"strand":"-","type":"gene"},"OPG040":{"end":25478,"seqid":"resources/genome_annotation.gff3","start":24351,"strand":"-","type":"gene"},"OPG042":{"end":27097,"seqid":"resources/genome_annotation.gff3","start":25823,"strand":"-","type":"gene"},"OPG043":{"end":27955,"seqid":"resources/genome_annotation.gff3","start":27125,"strand":"-","type":"gene"},"OPG044":{"end":28540,"seqid":"resources/genome_annotation.gff3","start":28091,"strand":"+","type":"gene"},"OPG045":{"end":29262,"seqid":"resources/genome_annotation.gff3","start":28603,"strand":"-","type":"gene"},"OPG046":{"end":29729,"seqid":"resources/genome_annotation.gff3","start":29274,"strand":"-","type":"gene"},"OPG047":{"end":31194,"seqid":"resources/genome_annotation.gff3","start":29746,"strand":"-","type":"gene"},"OPG048":{"end":32164,"seqid":"resources/genome_annotation.gff3","start":31205,"strand":"-","type":"gene"},"OPG049":{"end":33151,"seqid":"resources/genome_annotation.gff3","start":32195,"strand":"-","type":"gene"},"OPG050":{"end":33408,"seqid":"resources/genome_annotation.gff3","start":33181,"strand":"-","type":"gene"},"OPG051":{"end":33649,"seqid":"resources/genome_annotation.gff3","start":33425,"strand":"-","type":"gene"},"OPG052":{"end":33995,"seqid":"resources/genome_annotation.gff3","start":33801,"strand":"-","type":"gene"},"OPG053":{"end":34690,"seqid":"resources/genome_annotation.gff3","start":34052,"strand":"-","type":"gene"},"OPG054":{"end":35996,"seqid":"resources/genome_annotation.gff3","start":34677,"strand":"-","type":"gene"},"OPG055":{"end":37083,"seqid":"resources/genome_annotation.gff3","start":36019,"strand":"-","type":"gene"},"OPG056":{"end":39034,"seqid":"resources/genome_annotation.gff3","start":37127,"strand":"-","type":"gene"},"OPG057":{"end":40195,"seqid":"resources/genome_annotation.gff3","start":39077,"strand":"-","type":"gene"},"OPG058":{"end":40434,"seqid":"resources/genome_annotation.gff3","start":40213,"strand":"-","type":"gene"},"OPG059":{"end":40633,"seqid":"resources/genome_annotation.gff3","start":40484,"strand":"-","type":"gene"},"OPG060":{"end":41182,"seqid":"resources/genome_annotation.gff3","start":40706,"strand":"-","type":"gene"},"OPG061":{"end":41884,"seqid":"resources/genome_annotation.gff3","start":41189,"strand":"-","type":"gene"},"OPG062":{"end":42252,"seqid":"resources/genome_annotation.gff3","start":41947,"strand":"+","type":"gene"},"OPG063":{"end":43688,"seqid":"resources/genome_annotation.gff3","start":42249,"strand":"-","type":"gene"},"OPG064":{"end":45898,"seqid":"resources/genome_annotation.gff3","start":43685,"strand":"-","type":"gene"},"OPG065":{"end":46483,"seqid":"resources/genome_annotation.gff3","start":46022,"strand":"-","type":"gene"},"OPG066":{"end":47428,"seqid":"resources/genome_annotation.gff3","start":46649,"strand":"-","type":"gene"},"OPG068":{"end":49904,"seqid":"resources/genome_annotation.gff3","start":48201,"strand":"+","type":"gene"},"OPG069":{"end":50486,"seqid":"resources/genome_annotation.gff3","start":49986,"strand":"+","type":"gene"},"OPG070":{"end":51411,"seqid":"resources/genome_annotation.gff3","start":50590,"strand":"+","type":"gene"},"OPG071":{"end":54438,"seqid":"resources/genome_annotation.gff3","start":51418,"strand":"-","type":"gene"},"OPG072":{"end":54757,"seqid":"resources/genome_annotation.gff3","start":54470,"strand":"+","type":"gene"},"OPG073":{"end":55141,"seqid":"resources/genome_annotation.gff3","start":54752,"strand":"-","type":"gene"},"OPG074":{"end":57125,"seqid":"resources/genome_annotation.gff3","start":55128,"strand":"-","type":"gene"},"OPG075":{"end":57498,"seqid":"resources/genome_annotation.gff3","start":57172,"strand":"-","type":"gene"},"OPG076":{"end":57630,"seqid":"resources/genome_annotation.gff3","start":57523,"strand":"-","type":"gene"},"OPG077":{"end":58583,"seqid":"resources/genome_annotation.gff3","start":57645,"strand":"-","type":"gene"},"OPG078":{"end":58811,"seqid":"resources/genome_annotation.gff3","start":58590,"strand":"-","type":"gene"},"OPG079":{"end":59621,"seqid":"resources/genome_annotation.gff3","start":58812,"strand":"-","type":"gene"},"OPG080":{"end":62018,"seqid":"resources/genome_annotation.gff3","start":59703,"strand":"-","type":"gene"},"OPG081":{"end":62285,"seqid":"resources/genome_annotation.gff3","start":62046,"strand":"-","type":"gene"},"OPG082":{"end":63452,"seqid":"resources/genome_annotation.gff3","start":62304,"strand":"-","type":"gene"},"OPG083":{"end":64716,"seqid":"resources/genome_annotation.gff3","start":63445,"strand":"-","type":"gene"},"OPG084":{"end":66752,"seqid":"resources/genome_annotation.gff3","start":64722,"strand":"+","type":"gene"},"OPG085":{"end":68531,"seqid":"resources/genome_annotation.gff3","start":66756,"strand":"-","type":"gene"},"OPG086":{"end":68863,"seqid":"resources/genome_annotation.gff3","start":68528,"strand":"-","type":"gene"},"OPG087":{"end":69519,"seqid":"resources/genome_annotation.gff3","start":68857,"strand":"+","type":"gene"},"OPG088":{"end":69863,"seqid":"resources/genome_annotation.gff3","start":69489,"strand":"-","type":"gene"},"OPG089":{"end":71170,"seqid":"resources/genome_annotation.gff3","start":69866,"strand":"+","type":"gene"},"OPG090":{"end":71370,"seqid":"resources/genome_annotation.gff3","start":71179,"strand":"+","type":"gene"},"OPG091":{"end":71867,"seqid":"resources/genome_annotation.gff3","start":71370,"strand":"+","type":"gene"},"OPG092":{"end":72947,"seqid":"resources/genome_annotation.gff3","start":71832,"strand":"-","type":"gene"},"OPG093":{"end":73760,"seqid":"resources/genome_annotation.gff3","start":72978,"strand":"+","type":"gene"},"OPG094":{"end":74802,"seqid":"resources/genome_annotation.gff3","start":73780,"strand":"+","type":"gene"},"OPG095":{"end":75555,"seqid":"resources/genome_annotation.gff3","start":74803,"strand":"+","type":"gene"},"OPG096":{"end":75865,"seqid":"resources/genome_annotation.gff3","start":75587,"strand":"+","type":"gene"},"OPG097":{"end":76875,"seqid":"resources/genome_annotation.gff3","start":75841,"strand":"-","type":"gene"},"OPG098":{"end":77655,"seqid":"resources/genome_annotation.gff3","start":76900,"strand":"+","type":"gene"},"OPG099":{"end":78051,"seqid":"resources/genome_annotation.gff3","start":77665,"strand":"+","type":"gene"},"OPG100":{"end":78466,"seqid":"resources/genome_annotation.gff3","start":78008,"strand":"+","type":"gene"},"OPG101":{"end":79019,"seqid":"resources/genome_annotation.gff3","start":78486,"strand":"+","type":"gene"},"OPG102":{"end":80086,"seqid":"resources/genome_annotation.gff3","start":79085,"strand":"+","type":"gene"},"OPG103":{"end":80558,"seqid":"resources/genome_annotation.gff3","start":80001,"strand":"+","type":"gene"},"OPG104":{"end":81019,"seqid":"resources/genome_annotation.gff3","start":80618,"strand":"-","type":"gene"},"OPG105":{"end":84986,"seqid":"resources/genome_annotation.gff3","start":81126,"strand":"+","type":"gene"},"OPG106":{"end":85498,"seqid":"resources/genome_annotation.gff3","start":84983,"strand":"-","type":"gene"},"OPG107":{"end":86081,"seqid":"resources/genome_annotation.gff3","start":85512,"strand":"+","type":"gene"},"OPG108":{"end":87059,"seqid":"resources/genome_annotation.gff3","start":86085,"strand":"-","type":"gene"},"OPG109":{"end":89447,"seqid":"resources/genome_annotation.gff3","start":87060,"strand":"-","type":"gene"},"OPG110":{"end":90264,"seqid":"resources/genome_annotation.gff3","start":89632,"strand":"+","type":"gene"},"OPG111":{"end":91209,"seqid":"resources/genome_annotation.gff3","start":90265,"strand":"+","type":"gene"},"OPG112":{"end":91687,"seqid":"resources/genome_annotation.gff3","start":91247,"strand":"+","type":"gene"},"OPG113":{"end":94268,"seqid":"resources/genome_annotation.gff3","start":91731,"strand":"+","type":"gene"},"OPG114":{"end":94667,"seqid":"resources/genome_annotation.gff3","start":94227,"strand":"-","type":"gene"},"OPG115":{"end":95361,"seqid":"resources/genome_annotation.gff3","start":94660,"strand":"+","type":"gene"},"OPG116":{"end":96017,"seqid":"resources/genome_annotation.gff3","start":95361,"strand":"+","type":"gene"},"OPG117":{"end":98406,"seqid":"resources/genome_annotation.gff3","start":96049,"strand":"+","type":"gene"},"OPG118":{"end":100359,"seqid":"resources/genome_annotation.gff3","start":98446,"strand":"+","type":"gene"},"OPG119":{"end":100871,"seqid":"resources/genome_annotation.gff3","start":100386,"strand":"+","type":"gene"},"OPG120":{"end":101748,"seqid":"resources/genome_annotation.gff3","start":100834,"strand":"-","type":"gene"},"OPG121":{"end":102431,"seqid":"resources/genome_annotation.gff3","start":101790,"strand":"+","type":"gene"},"OPG122":{"end":103174,"seqid":"resources/genome_annotation.gff3","start":102428,"strand":"+","type":"gene"},"OPG123":{"end":105070,"seqid":"resources/genome_annotation.gff3","start":103175,"strand":"-","type":"gene"},"OPG124":{"end":105968,"seqid":"resources/genome_annotation.gff3","start":105105,"strand":"-","type":"gene"},"OPG125":{"end":107654,"seqid":"resources/genome_annotation.gff3","start":105999,"strand":"-","type":"gene"},"OPG126":{"end":108130,"seqid":"resources/genome_annotation.gff3","start":107678,"strand":"-","type":"gene"},"OPG127":{"end":108825,"seqid":"resources/genome_annotation.gff3","start":108151,"strand":"-","type":"gene"},"OPG128":{"end":109055,"seqid":"resources/genome_annotation.gff3","start":108822,"strand":"-","type":"gene"},"OPG129":{"end":111004,"seqid":"resources/genome_annotation.gff3","start":109070,"strand":"-","type":"gene"},"OPG130":{"end":111902,"seqid":"resources/genome_annotation.gff3","start":111057,"strand":"-","type":"gene"},"OPG131":{"end":112425,"seqid":"resources/genome_annotation.gff3","start":111940,"strand":"+","type":"gene"},"OPG132":{"end":113540,"seqid":"resources/genome_annotation.gff3","start":112422,"strand":"-","type":"gene"},"OPG133":{"end":115696,"seqid":"resources/genome_annotation.gff3","start":113564,"strand":"-","type":"gene"},"OPG134":{"end":116628,"seqid":"resources/genome_annotation.gff3","start":115750,"strand":"+","type":"gene"},"OPG135":{"end":116911,"seqid":"resources/genome_annotation.gff3","start":116609,"strand":"-","type":"gene"},"OPG136":{"end":119587,"seqid":"resources/genome_annotation.gff3","start":116912,"strand":"-","type":"gene"},"OPG137":{"end":120558,"seqid":"resources/genome_annotation.gff3","start":119602,"strand":"+","type":"gene"},"OPG138":{"end":121132,"seqid":"resources/genome_annotation.gff3","start":120560,"strand":"-","type":"gene"},"OPG139":{"end":121368,"seqid":"resources/genome_annotation.gff3","start":121156,"strand":"-","type":"gene"},"OPG140":{"end":121746,"seqid":"resources/genome_annotation.gff3","start":121474,"strand":"-","type":"gene"},"OPG141":{"end":121924,"seqid":"resources/genome_annotation.gff3","start":121763,"strand":"-","type":"gene"},"OPG142":{"end":122198,"seqid":"resources/genome_annotation.gff3","start":121914,"strand":"-","type":"gene"},"OPG143":{"end":123315,"seqid":"resources/genome_annotation.gff3","start":122182,"strand":"-","type":"gene"},"OPG144":{"end":123932,"seqid":"resources/genome_annotation.gff3","start":123318,"strand":"-","type":"gene"},"OPG145":{"end":125425,"seqid":"resources/genome_annotation.gff3","start":123947,"strand":"+","type":"gene"},"OPG146":{"end":125639,"seqid":"resources/genome_annotation.gff3","start":125406,"strand":"-","type":"gene"},"OPG147":{"end":125987,"seqid":"resources/genome_annotation.gff3","start":125640,"strand":"-","type":"gene"},"OPG148":{"end":127266,"seqid":"resources/genome_annotation.gff3","start":125986,"strand":"+","type":"gene"},"OPG149":{"end":127759,"seqid":"resources/genome_annotation.gff3","start":127196,"strand":"+","type":"gene"},"OPG150":{"end":128927,"seqid":"resources/genome_annotation.gff3","start":127779,"strand":"+","type":"gene"},"OPG151":{"end":132418,"seqid":"resources/genome_annotation.gff3","start":128924,"strand":"+","type":"gene"},"OPG153":{"end":137667,"seqid":"resources/genome_annotation.gff3","start":136138,"strand":"-","type":"gene"},"OPG154":{"end":138050,"seqid":"resources/genome_annotation.gff3","start":137718,"strand":"-","type":"gene"},"OPG155":{"end":138491,"seqid":"resources/genome_annotation.gff3","start":138051,"strand":"-","type":"gene"},"OPG156":{"end":139409,"seqid":"resources/genome_annotation.gff3","start":138492,"strand":"-","type":"gene"},"OPG157":{"end":139608,"seqid":"resources/genome_annotation.gff3","start":139372,"strand":"-","type":"gene"},"OPG158":{"end":139769,"seqid":"resources/genome_annotation.gff3","start":139641,"strand":"-","type":"gene"},"OPG159":{"end":140205,"seqid":"resources/genome_annotation.gff3","start":139768,"strand":"+","type":"gene"},"OPG160":{"end":141074,"seqid":"resources/genome_annotation.gff3","start":140172,"strand":"-","type":"gene"},"OPG161":{"end":141647,"seqid":"resources/genome_annotation.gff3","start":141102,"strand":"+","type":"gene"},"OPG162":{"end":142158,"seqid":"resources/genome_annotation.gff3","start":141652,"strand":"+","type":"gene"},"OPG163":{"end":142732,"seqid":"resources/genome_annotation.gff3","start":142202,"strand":"+","type":"gene"},"OPG164":{"end":143464,"seqid":"resources/genome_annotation.gff3","start":142778,"strand":"+","type":"gene"},"OPG165":{"end":144322,"seqid":"resources/genome_annotation.gff3","start":143516,"strand":"+","type":"gene"},"OPG166":{"end":144577,"seqid":"resources/genome_annotation.gff3","start":144398,"strand":"+","type":"gene"},"OPG167":{"end":145407,"seqid":"resources/genome_annotation.gff3","start":144574,"strand":"-","type":"gene"},"OPG170":{"end":146778,"seqid":"resources/genome_annotation.gff3","start":146113,"strand":"-","type":"gene"},"OPG171":{"end":147389,"seqid":"resources/genome_annotation.gff3","start":146988,"strand":"+","type":"gene"},"OPG172":{"end":148017,"seqid":"resources/genome_annotation.gff3","start":147427,"strand":"+","type":"gene"},"OPG173":{"end":148261,"seqid":"resources/genome_annotation.gff3","start":148037,"strand":"+","type":"gene"},"OPG174":{"end":149395,"seqid":"resources/genome_annotation.gff3","start":148355,"strand":"-","type":"gene"},"OPG175":{"end":149819,"seqid":"resources/genome_annotation.gff3","start":149442,"strand":"+","type":"gene"},"OPG176":{"end":150531,"seqid":"resources/genome_annotation.gff3","start":149809,"strand":"+","type":"gene"},"OPG178":{"end":152123,"seqid":"resources/genome_annotation.gff3","start":151509,"strand":"+","type":"gene"},"OPG180":{"end":154371,"seqid":"resources/genome_annotation.gff3","start":152692,"strand":"+","type":"gene"},"OPG181":{"end":155416,"seqid":"resources/genome_annotation.gff3","start":154412,"strand":"+","type":"gene"},"OPG185":{"end":159858,"seqid":"resources/genome_annotation.gff3","start":158917,"strand":"+","type":"gene"},"OPG187":{"end":161533,"seqid":"resources/genome_annotation.gff3","start":160622,"strand":"+","type":"gene"},"OPG188":{"end":163107,"seqid":"resources/genome_annotation.gff3","start":161596,"strand":"+","type":"gene"},"OPG189":{"end":165018,"seqid":"resources/genome_annotation.gff3","start":163333,"strand":"+","type":"gene"},"OPG190":{"end":166075,"seqid":"resources/genome_annotation.gff3","start":165122,"strand":"+","type":"gene"},"OPG191":{"end":166667,"seqid":"resources/genome_annotation.gff3","start":166161,"strand":"+","type":"gene"},"OPG192":{"end":167279,"seqid":"resources/genome_annotation.gff3","start":166731,"strand":"+","type":"gene"},"OPG193":{"end":168137,"seqid":"resources/genome_annotation.gff3","start":167334,"strand":"+","type":"gene"},"OPG195":{"end":168895,"seqid":"resources/genome_annotation.gff3","start":168230,"strand":"+","type":"gene"},"OPG197":{"end":169972,"seqid":"resources/genome_annotation.gff3","start":169670,"strand":"+","type":"gene"},"OPG198":{"end":170886,"seqid":"resources/genome_annotation.gff3","start":170038,"strand":"+","type":"gene"},"OPG199":{"end":172022,"seqid":"resources/genome_annotation.gff3","start":170988,"strand":"+","type":"gene"},"OPG200":{"end":172599,"seqid":"resources/genome_annotation.gff3","start":172150,"strand":"+","type":"gene"},"OPG204":{"end":175587,"seqid":"resources/genome_annotation.gff3","start":174532,"strand":"+","type":"gene"},"OPG205":{"end":178019,"seqid":"resources/genome_annotation.gff3","start":175656,"strand":"+","type":"gene"},"OPG208":{"end":180339,"seqid":"resources/genome_annotation.gff3","start":179266,"strand":"+","type":"gene"},"OPG209":{"end":181090,"seqid":"resources/genome_annotation.gff3","start":180518,"strand":"+","type":"gene"},"OPG210":{"end":186998,"seqid":"resources/genome_annotation.gff3","start":181356,"strand":"+","type":"gene"},"nuc":{"end":197209,"start":1,"strand":"+","type":"source"}},"colorings":[{"key":"clade_membership","title":"Clade","type":"categorical","scale":[["IIb","#DEA73C"]]},{"key":"gt","title":"Genotype","type":"categorical"},{"key":"outbreak","title":"Outbreak","type":"categorical","scale":[["hMPXV-1","#4C90C0"]]},{"key":"lineage","title":"Lineage","type":"categorical","scale":[["B.1","#4041C7"],["B.1.1","#3F53CD"],["B.1.2","#4064CF"],["B.1.3","#4375CD"],["C.1","#4784C8"],["B.1.4","#4C91BF"],["B.1.5","#539CB4"],["B.1.6","#5AA5A7"],["B.1.7","#63AC9A"],["B.1.8","#6CB28C"],["B.1.9","#77B67E"],["B.1.10","#82BA71"],["B.1.11","#8FBC66"],["B.1.12","#9CBE5B"],["B.1.13","#A9BD53"],["B.1.14","#B5BD4C"],["B.1.15","#C1BA46"],["B.1.16","#CDB642"],["B.1.17","#D6B03F"],["B.1.18","#DEA73B"],["B.1.19","#E39B39"],["B.1.20","#E68D36"]]},{"key":"date","title":"Collection Date","type":"categorical"},{"key":"host","title":"Host","type":"categorical"},{"key":"strain","title":"Strain name","type":"categorical"},{"key":"strain_display","title":"Pretty strain name","type":"categorical"},{"key":"region","title":"Region","type":"categorical","scale":[["Asia","#447CCD"],["Oceania","#5EA9A1"],["Africa","#8ABB6A"],["Europe","#BEBB48"],["South America","#E29E39"],["North America","#E2562B"]]},{"key":"country","title":"Country","type":"categorical","scale":[["Israel","#5E1D9D"],["Taiwan","#4D23AE"],["South Korea","#4432BD"],["Japan","#3F43C7"],["Australia","#3F56CE"],["South Africa","#4067CF"],["Portugal","#4379CD"],["Ireland","#4887C6"],["Spain","#4E95BD"],["United Kingdom","#559FB0"],["France","#5DA8A3"],["Belgium","#67AE94"],["Netherlands","#71B486"],["Switzerland","#7CB878"],["Germany","#89BB6B"],["Italy","#96BD60"],["Slovenia","#A3BE57"],["Sweden","#B1BD4E"],["Austria","#BDBB48"],["Czech Republic","#CAB843"],["Slovakia","#D3B23F"],["Romania","#DDAA3C"],["Finland","#E29E39"],["Brazil","#E69036"],["Peru","#E67F33"],["Colombia","#E56B2F"],["Mexico","#E1552B"],["USA","#DE3E27"],["Canada","#DB2823"]]}],"filters":["clade_membership","lineage","country","host","institution","region","strain_display","strain","date","outbreak"],"panels":["tree","entropy"],"extensions":{"nextclade":{"clade_node_attrs":[{"name":"outbreak","displayName":"Outbreak","description":""},{"name":"lineage","displayName":"Lineage","description":""}],"placement_mask_ranges":[{"begin":0,"end":1500},{"begin":133050,"end":133250},{"begin":136500,"end":136600},{"begin":140050,"end":140250},{"begin":146750,"end":147000},{"begin":150500,"end":150650},{"begin":169250,"end":169500},{"begin":169700,"end":169800},{"begin":173150,"end":173350},{"begin":179000,"end":179300},{"begin":190787,"end":197209}]}}},"tree":{"name":"NODE_0000001","node_attrs":{"div":0,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{},"labels":{"clade":"B.1"}},"children":[{"name":"ref_in_coord","node_attrs":{"div":0,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000000","node_attrs":{"div":0,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T607-","T608-","T609-","T133177-","C133178-","T133179-","T133180-","T133181-","C133182-","T133183-","C133184-","A133185-","A133186-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A196615-","A196616-","A196617-"]}},"children":[{"name":"ON682267","node_attrs":{"div":0,"accession":"ON682267","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI010"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON682267/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP205139","node_attrs":{"div":0,"accession":"OP205139","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000090"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205139/2022-05-25"},"date":{"value":"2022-05-25"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON880546","node_attrs":{"div":0,"accession":"ON880546","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3368/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880546/2022-06-02"},"date":{"value":"2022-06-02"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"ON631241","node_attrs":{"div":0,"accession":"ON631241","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"2022/2 SLO"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia"},"strain_display":{"value":"Slovenia/ON631241/2022-05-24"},"date":{"value":"2022-05-24"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON838940","node_attrs":{"div":0,"accession":"ON838940","author":{"author":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J.","value":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"4061"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Hospital Universitario La Paz, Microbiology"},"strain_display":{"value":"Spain/ON838940/2022-05-20"},"date":{"value":"2022-05-20"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP689666","node_attrs":{"div":0,"accession":"OP689666","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI513"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP689666/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR035655","node_attrs":{"div":0,"accession":"OR035655","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_49"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035655/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON983166","node_attrs":{"div":0,"accession":"ON983166","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3702/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON983166/2022-06-15"},"date":{"value":"2022-06-15"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OR035652","node_attrs":{"div":0,"accession":"OR035652","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_46"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035652/2022-08-02"},"date":{"value":"2022-08-02"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON808414","node_attrs":{"div":0,"accession":"ON808414","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"CVR_MPXV1b"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"strain_display":{"value":"United Kingdom/ON808414/2022-05-15"},"date":{"value":"2022-05-15"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"ON782022","node_attrs":{"div":0,"accession":"ON782022","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.,Sironen,T.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.,Sironen,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX-42/Finland/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"strain_display":{"value":"Finland/ON782022/2022-05-31"},"date":{"value":"2022-05-31"},"country":{"value":"Finland"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OP382480","node_attrs":{"div":0,"accession":"OP382480","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00003"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382480/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP415195","node_attrs":{"div":0,"accession":"OP415195","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_96X1Vd_9000217"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415195/2022-03-XX"},"date":{"value":"2022-03-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP225969","node_attrs":{"div":0,"accession":"OP225969","author":{"author":"Gigante,C.M.,Ghinai,I.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.M.,Ghinai,I.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_IL0025"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP225969/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"ON880508","node_attrs":{"div":0,"accession":"ON880508","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3127/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880508/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"ON627808","node_attrs":{"div":0,"accession":"ON627808","author":{"author":"Young,E.L.,Hergert,J.,Oakeson,K.F.","value":"Young,E.L.,Hergert,J.,Oakeson,K.F."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/human/USA/UT-UPHL-82200022/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Department of Health, Utah Public Health Laboratory, USA"},"strain_display":{"value":"USA/ON627808/2022-05-20"},"date":{"value":"2022-05-20"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"ON803429","node_attrs":{"div":0,"accession":"ON803429","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2873/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON803429/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR087011","node_attrs":{"div":0,"accession":"OR087011","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_202/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR087011/2022-08-08"},"date":{"value":"2022-08-08"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON880421","node_attrs":{"div":0,"accession":"ON880421","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/UZ_REGA_5/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Rega Institute, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/ON880421/2022-05-27"},"date":{"value":"2022-05-27"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON755040","node_attrs":{"div":0,"accession":"ON755040","author":{"author":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O.","value":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_IRBA22-14"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IRBA, D.DNRBC/D.2MI/U.BACT"},"strain_display":{"value":"France/ON755040/2022-05-20"},"date":{"value":"2022-05-20"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON880420","node_attrs":{"div":0,"accession":"ON880420","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/UZ_REGA_4/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Rega Institute, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/ON880420/2022-05-27"},"date":{"value":"2022-05-27"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON808417","node_attrs":{"div":0,"accession":"ON808417","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"CVR_MPXV1e"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"strain_display":{"value":"United Kingdom/ON808417/2022-05-15"},"date":{"value":"2022-05-15"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"ON649720","node_attrs":{"div":0,"accession":"ON649720","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0024/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"strain_display":{"value":"Portugal/ON649720/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"ON676703","node_attrs":{"div":0,"accession":"ON676703","author":{"author":"Gigante,C.M.,Ventura,J.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y.","value":"Gigante,C.M.,Ventura,J.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_CA001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"strain_display":{"value":"USA/ON676703/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON880422","node_attrs":{"div":0,"accession":"ON880422","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/UZ_REGA_6/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Rega Institute, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/ON880422/2022-05-27"},"date":{"value":"2022-05-27"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR759162","node_attrs":{"div":0,"accession":"OR759162","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL074/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759162/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["G850A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C196360T"]}}},{"name":"OP382482","node_attrs":{"div":0,"accession":"OP382482","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00005"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382482/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035663","node_attrs":{"div":0,"accession":"OR035663","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_57"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035663/2022-06-09"},"date":{"value":"2022-06-09"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP205117","node_attrs":{"div":0,"accession":"OP205117","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000159"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205117/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON803438","node_attrs":{"div":0,"accession":"ON803438","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2897/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON803438/2022-05-20"},"date":{"value":"2022-05-20"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP536747","node_attrs":{"div":0,"accession":"OP536747","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000365"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536747/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035654","node_attrs":{"div":0,"accession":"OR035654","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_48"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035654/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP205114","node_attrs":{"div":0,"accession":"OP205114","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000152"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205114/2022-05-16"},"date":{"value":"2022-05-16"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035713","node_attrs":{"div":0,"accession":"OR035713","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_107"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035713/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON880419","node_attrs":{"div":0,"accession":"ON880419","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/UZ_REGA_3/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Rega Institute, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/ON880419/2022-05-27"},"date":{"value":"2022-05-27"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035704","node_attrs":{"div":0,"accession":"OR035704","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_98"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035704/2022-05-31"},"date":{"value":"2022-05-31"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G179023A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON649879","node_attrs":{"div":0,"accession":"ON649879","author":{"author":"Israeli,O.,Guedj-Dana,Y.,Lazar,S.,Shifman,O.,Erez,N.,Weiss,S.,Paran,N.,Israely,T.,Schuster,O.,Zvi,A.,Beth-Din,A.,Cohen Gihon,I.","value":"Israeli,O.,Guedj-Dana,Y.,Lazar,S.,Shifman,O.,Erez,N.,Weiss,S.,Paran,N.,Israely,T.,Schuster,O.,Zvi,A.,Beth-Din,A.,Cohen Gihon,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_ISR001_2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Biochemistry & Molecular Genetics, Israel Institute for Biological Research, Israel"},"strain_display":{"value":"Israel/ON649879/2022-05-20"},"date":{"value":"2022-05-20"},"country":{"value":"Israel"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"ON880530","node_attrs":{"div":0,"accession":"ON880530","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3162/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880530/2022-05-29"},"date":{"value":"2022-05-29"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"OR264442","node_attrs":{"div":0,"accession":"OR264442","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"60_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264442/2022-08-22"},"date":{"value":"2022-08-22"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["C173173T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035678","node_attrs":{"div":0,"accession":"OR035678","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_72"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035678/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON563414","node_attrs":{"div":0,"accession":"ON563414","author":{"author":"Gigante,C.M.,Smole,S.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Brown,C.,Li,Y.","value":"Gigante,C.M.,Smole,S.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Brown,C.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_MA001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"strain_display":{"value":"USA/ON563414/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON585034","node_attrs":{"div":0,"accession":"ON585034","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0007/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"strain_display":{"value":"Portugal/ON585034/2022-05-15"},"date":{"value":"2022-05-15"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A188351-"]}}},{"name":"OP160532","node_attrs":{"div":1,"accession":"OP160532","author":{"author":"Tutu van Furth AM,van der Kuip M,van Els AL,Fievez LC,van Rijckevorsel GG,van den Ouden A,Jonges M,Welkers MR,Welkers,M.,Jonges,M.","value":"Tutu van Furth AM,van der Kuip M,van Els AL,Fievez LC,van Rijckevorsel GG,van den Ouden A,Jonges M,Welkers MR,Welkers,M.,Jonges,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Netherlands/NH-AUMC-0001/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention"},"strain_display":{"value":"Netherlands/OP160532/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Netherlands"}},"branch_attrs":{"mutations":{"nuc":["A148207T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G191845A","A196614-"],"OPG173":["E57D"]},"labels":{"aa":"OPG173: E57D"}}},{"name":"OP150926","node_attrs":{"div":0,"accession":"OP150926","author":{"author":"Gigante,C.,Goldoft,M.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Holshue,M.,Li,Y.","value":"Gigante,C.,Goldoft,M.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Holshue,M.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_PA001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP150926/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP133007","node_attrs":{"div":2,"accession":"OP133007","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1536480/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP133007/2022-07-22"},"date":{"value":"2022-07-22"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{"nuc":["A28532-","G32715A","G110407A","T133099-","T133100-","T133101-","T133102-","A173189G","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG044":["M148-"],"OPG049":["S146F"]},"labels":{"aa":"OPG044: M148-; OPG049: S146F"}}},{"name":"OP120937","node_attrs":{"div":1,"accession":"OP120937","author":{"author":"Aja-Macaya,P.,Rumbo-Feal,S.,Poza,M.,Canizares,A.,Vallejo,J.A.,Bou,G.","value":"Aja-Macaya,P.,Rumbo-Feal,S.,Poza,M.,Canizares,A.,Vallejo,J.A.,Bou,G."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MP01CHUAC"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Biomedical research institute (INIBIC), Microbiology"},"strain_display":{"value":"Spain/OP120937/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["G150330A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP133006","node_attrs":{"div":4,"accession":"OP133006","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1532243/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP133006/2022-07-06"},"date":{"value":"2022-07-06"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{"nuc":["A28532-","C122511T","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","G151801A","C153984T","G169886A","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG044":["M148-"],"OPG143":["E269K"],"OPG178":["G98E"],"OPG197":["E73K"]},"labels":{"aa":"OPG044: M148-; OPG143: E269K; OPG178: G98E; OPG197: E73K"}}},{"name":"OP062232","node_attrs":{"div":1,"accession":"OP062232","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Jolly,G.,Griffiths,E.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Jolly,G.,Griffiths,E.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3909/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP062232/2022-06-27"},"date":{"value":"2022-06-27"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T","G75169A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG095":["D123N"]},"labels":{"aa":"OPG095: D123N"}}},{"name":"OP022170","node_attrs":{"div":1,"accession":"OP022170","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_5"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP022170/2022-05-16"},"date":{"value":"2022-05-16"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C178569T","-179183T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OP022171","node_attrs":{"div":0,"accession":"OP022171","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_6"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP022171/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179208C","-179209A","-179210T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"ON959134","node_attrs":{"div":1,"accession":"ON959134","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_NY003"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"strain_display":{"value":"USA/ON959134/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C98368T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON927243","node_attrs":{"div":1,"accession":"ON927243","author":{"author":"Palomino-Cabrera,R.,Penas-Utrilla,D.,Buenestado-Serrano,S.,Perez-Lago,L.,Herranz Martin,M.,Veintimilla,C.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Palomino-Cabrera,R.,Penas-Utrilla,D.,Buenestado-Serrano,S.,Perez-Lago,L.,Herranz Martin,M.,Veintimilla,C.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/Spain/MD-HGUGM-6642566/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"HGUGM, Microbial Genomics"},"strain_display":{"value":"Spain/ON927243/2022-06-21"},"date":{"value":"2022-06-21"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","C187154T"]}}},{"name":"ON880543","node_attrs":{"div":3,"accession":"ON880543","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3357/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880543/2022-06-02"},"date":{"value":"2022-06-02"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["T606-","C17810T","G62130A","C157792T","A196614-"],"OPG030":["M8I"]},"labels":{"aa":"OPG030: M8I"}}},{"name":"ON880531","node_attrs":{"div":0,"accession":"ON880531","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3165/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880531/2022-05-29"},"date":{"value":"2022-05-29"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"ON880521","node_attrs":{"div":0,"accession":"ON880521","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2858/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880521/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"ON880525","node_attrs":{"div":0,"accession":"ON880525","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3086/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880525/2022-05-25"},"date":{"value":"2022-05-25"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"ON880509","node_attrs":{"div":0,"accession":"ON880509","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3137/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880509/2022-05-29"},"date":{"value":"2022-05-29"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"ON872184","node_attrs":{"div":5,"accession":"ON872184","author":{"author":"Fletcher,N.,Gonzalez,G.,Meredith,L.,Purves,K.,Carr,M.,Dean,J.,Keogan,B.,Crowley,B.,Lyons,F.,O'Reilly,S.,Gautier,V.,Mallon,P.,Gordon,S.,Connell,J.,De Gascun,C.F.","value":"Fletcher,N.,Gonzalez,G.,Meredith,L.,Purves,K.,Carr,M.,Dean,J.,Keogan,B.,Crowley,B.,Lyons,F.,O'Reilly,S.,Gautier,V.,Mallon,P.,Gordon,S.,Connell,J.,De Gascun,C.F."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"WA-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University College Dublin, National Virus Reference Laboratory"},"strain_display":{"value":"Ireland/ON872184/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Ireland"}},"branch_attrs":{"mutations":{"nuc":["T48785C","G49636A","C50017T","T72809C","G178541A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG068":["G479E"],"OPG069":["T11I"],"OPG092":["K47E"]},"labels":{"aa":"OPG068: G479E; OPG069: T11I; OPG092: K47E"}}},{"name":"ON838939","node_attrs":{"div":2,"accession":"ON838939","author":{"author":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J.","value":"de la Hoz-Sanchez,B.,Lopez-Ortiz,M.,Gutierrez-Arroyo,A.,Roces-Alvarez,P.,Lazaro-Peona,F.,Dahdouh,E.,Bloise,I.,Garcia-Rodriguez,J.,Mingorance,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"8887"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Hospital Universitario La Paz, Microbiology"},"strain_display":{"value":"Spain/ON838939/2022-06-06"},"date":{"value":"2022-06-06"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["G90838A","G94328A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG111":["D192N"]},"labels":{"aa":"OPG111: D192N"}}},{"name":"ON843171","node_attrs":{"div":0,"accession":"ON843171","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0030/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/ON843171/2022-05-26"},"date":{"value":"2022-05-26"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C133103T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON843164","node_attrs":{"div":0,"accession":"ON843164","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0037/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/ON843164/2022-05-18"},"date":{"value":"2022-05-18"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C133103T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON808416","node_attrs":{"div":1,"accession":"ON808416","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"CVR_MPXV1d"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"strain_display":{"value":"United Kingdom/ON808416/2022-05-15"},"date":{"value":"2022-05-15"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["G20576A","T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"ON808415","node_attrs":{"div":0,"accession":"ON808415","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"CVR_MPXV1c"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"strain_display":{"value":"United Kingdom/ON808415/2022-05-15"},"date":{"value":"2022-05-15"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"ON803444","node_attrs":{"div":1,"accession":"ON803444","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2969/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON803444/2022-05-24"},"date":{"value":"2022-05-24"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["G21069A"]}}},{"name":"ON803427","node_attrs":{"div":0,"accession":"ON803427","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2861/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON803427/2022-05-18"},"date":{"value":"2022-05-18"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON803436","node_attrs":{"div":0,"accession":"ON803436","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2894/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON803436/2022-05-20"},"date":{"value":"2022-05-20"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["G143768-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG165":["G85-"]},"labels":{"aa":"OPG165: G85-"}}},{"name":"ON780016","node_attrs":{"div":0,"accession":"ON780016","author":{"author":"Rueca,M.,Giombini,E.,Gruber,C.E.M.,Gramigna,G.,Mazzotta,V.,Carletti,F.,Lapa,D.,Pittalis,S.,Puro,V.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F.","value":"Rueca,M.,Giombini,E.,Gruber,C.E.M.,Gramigna,G.,Mazzotta,V.,Carletti,F.,Lapa,D.,Pittalis,S.,Puro,V.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"INMI-Pt3"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology"},"strain_display":{"value":"Italy/ON780016/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A"]}}},{"name":"ON745215","node_attrs":{"div":0,"accession":"ON745215","author":{"author":"Giombini,E.,Gruber,C.E.M.,Rueca,M.,Gramigna,G.,VIta,S.,Carletti,F.,D'Abramo,A.,Lapa,D.,Puro,V.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Specchiarello,E.,Vairo,F.,Vaia,F.,Garbuglia,A.R.,Nicastri,E.,Antinori,A.,GIrardi,E.,Maggi,F.","value":"Giombini,E.,Gruber,C.E.M.,Rueca,M.,Gramigna,G.,VIta,S.,Carletti,F.,D'Abramo,A.,Lapa,D.,Puro,V.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Specchiarello,E.,Vairo,F.,Vaia,F.,Garbuglia,A.R.,Nicastri,E.,Antinori,A.,GIrardi,E.,Maggi,F."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"INMI-Pt2"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology"},"strain_display":{"value":"Italy/ON745215/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["T591A","A592-","T593-","T595A","-607T","-608T","-609T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A"]}}},{"name":"ON745225","node_attrs":{"div":1,"accession":"ON745225","author":{"author":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/Spain/MD-HGUGM-66649483/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"HGUGM, Microbial Genomics"},"strain_display":{"value":"Spain/ON745225/2022-05-27"},"date":{"value":"2022-05-27"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["G50151A","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG069":["D56N"]},"labels":{"aa":"OPG069: D56N"}}},{"name":"ON682265","node_attrs":{"div":0,"accession":"ON682265","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI04"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON682265/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON682268","node_attrs":{"div":1,"accession":"ON682268","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI08"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON682268/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G4454A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C192756T"],"OPG003":["H52Y"],"OPG003_dup":["H52Y"]},"labels":{"aa":"OPG003: H52Y; OPG003_dup: H52Y"}}},{"name":"ON676705","node_attrs":{"div":1,"accession":"ON676705","author":{"author":"Gigante,C.M.,Atkinson,A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Murray,J.,Li,Y.","value":"Gigante,C.M.,Atkinson,A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Murray,J.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_UT001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"strain_display":{"value":"USA/ON676705/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","G28330A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG044":["M80I"]},"labels":{"aa":"OPG044: M80I"}}},{"name":"ON676706","node_attrs":{"div":0,"accession":"ON676706","author":{"author":"Gigante,C.M.,Atkinson,A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Murray,J.,Li,Y.","value":"Gigante,C.M.,Atkinson,A.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Murray,J.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_UT002"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"strain_display":{"value":"USA/ON676706/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","T133102-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON676708","node_attrs":{"div":14,"accession":"ON676708","author":{"author":"Gigante,C.M.,Myers,R.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Blythe,D.,Li,Y.","value":"Gigante,C.M.,Myers,R.,Seabolt,M.H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Blythe,D.,Li,Y."},"strain":{"value":"MPXV_USA_2021_MD"},"clade_membership":{"value":"outgroup"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Division of High-Consequence Pathogens & Pathology, Centers for Disease Control & Prevention (US CDC), USA"},"strain_display":{"value":"USA/ON676708/2021-11-XX"},"date":{"value":"2021-11-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A3111G","T39139C","A73239G","A74205G","A77383G","C79348T","T84587C","C86979T","C133714T","T150469C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C151461A","A155795G","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","A170262G","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T183519C","T194099C"],"OPG057":["K353E"],"OPG093":["N88D"],"OPG094":["I142M"],"OPG098":["K162E"],"OPG176":["Y221H"],"OPG197":["T34-","D35-"],"OPG210":["S722P"]},"labels":{"aa":"OPG057: K353E; OPG093: N88D; OPG094: I142M; OPG098: K162E; OPG176: Y221H; OPG197: T34-, D35-; OPG210: S722P","clade":"outgroup"}}},{"name":"ON649717","node_attrs":{"div":1,"accession":"ON649717","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0019/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"strain_display":{"value":"Portugal/ON649717/2022-05-21"},"date":{"value":"2022-05-21"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C118296T"],"OPG136":["R431K"]},"labels":{"aa":"OPG136: R431K"}}},{"name":"ON644344","node_attrs":{"div":0,"accession":"ON644344","author":{"author":"Licastro,D.,DeGasperi,M.,Negri,C.,Piscianz,E.,Koncan,R.,Dal Monego,S.,Segat,L.,D'Agaro,P.","value":"Licastro,D.,DeGasperi,M.,Negri,C.,Piscianz,E.,Koncan,R.,Dal Monego,S.,Segat,L.,D'Agaro,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_FVG-ITA_01_2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Genomics & Epigenomics, AREA Science Park, Italy"},"strain_display":{"value":"Italy/ON644344/2022-05-25"},"date":{"value":"2022-05-25"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["C334-","A335-","C133077T","T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T173317-","G173318-","G173319-","G173320-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON619838","node_attrs":{"div":2,"accession":"ON619838","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_4"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Research & Evaluation, UKHSA, UK"},"strain_display":{"value":"United Kingdom/ON619838/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C147011T","G172095A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"ON622712","node_attrs":{"div":1,"accession":"ON622712","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/UZ_REGA_1/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Microbiology, Immunology & Transplantation, KU Leuven, Rega Institute, Belgium"},"strain_display":{"value":"Belgium/ON622712/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C46125T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG065":["R120K"]},"labels":{"aa":"OPG065: R120K"}}},{"name":"ON619836","node_attrs":{"div":2,"accession":"ON619836","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_2"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Research & Evaluation, UKHSA, UK"},"strain_display":{"value":"United Kingdom/ON619836/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C7259T","C33832T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG052":["R55Q"]},"labels":{"aa":"OPG052: R55Q"}}},{"name":"ON622720","node_attrs":{"div":0,"accession":"ON622720","author":{"author":"Laubscher,F.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Schibler,M.,Kaiser,L.,Renzoni,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-CH-38156923/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Laboratory of Viorology, University Hospital of Geneva, Switzerland"},"strain_display":{"value":"Switzerland/ON622720/2022-05-24"},"date":{"value":"2022-05-24"},"country":{"value":"Switzerland"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON619835","node_attrs":{"div":0,"accession":"ON619835","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Pullan,S.T.,Carter,D.P.,Crook,J.M.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Research & Evaluation, UKHSA, UK"},"strain_display":{"value":"United Kingdom/ON619835/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179179T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"ON614676","node_attrs":{"div":0,"accession":"ON614676","author":{"author":"Gruber,C.E.M.,Rueca,M.,Gramigna,G.,Carletti,F.,Butera,O.,Fabeni,L.,Specchiarello,E.,Meschi,S.,Colavita,F.,Minosse,C.,Francalancia,M.,Lapa,D.,Garbuglia,A.R.,Giombini,E.","value":"Gruber,C.E.M.,Rueca,M.,Gramigna,G.,Carletti,F.,Butera,O.,Fabeni,L.,Specchiarello,E.,Meschi,S.,Colavita,F.,Minosse,C.,Francalancia,M.,Lapa,D.,Garbuglia,A.R.,Giombini,E."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"INMI-Pt1"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Laboratory of Virology, INMI Lazzaro Spallanzani IRCCS, Italy"},"strain_display":{"value":"Italy/ON614676/2022-05-18"},"date":{"value":"2022-05-18"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"ON615424","node_attrs":{"div":2,"accession":"ON615424","author":{"author":"Oude Munnink,B.B.,Boter,M.,Wellers,B.,Molenkamp,R.,Sikkema,R.S.,Koopmans,M.","value":"Oude Munnink,B.B.,Boter,M.,Wellers,B.,Molenkamp,R.,Sikkema,R.S.,Koopmans,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_2022_NL001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Public Health Virology, Erasmus Medical Centre, The Netherlands"},"strain_display":{"value":"Netherlands/ON615424/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Netherlands"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155611A","G171003A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","G179362-","G179363-","-196615A"],"OPG199":["E6K"]},"labels":{"aa":"OPG199: E6K"}}},{"name":"ON595760","node_attrs":{"div":0,"accession":"ON595760","author":{"author":"Laubscher,F.,Chudzinski,V.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinski,V.,Schibler,M.,Kaiser,L.,Renzoni,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-CH-38134631/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Laboratory of Viorology, University Hospital of Geneva, Switzerland"},"strain_display":{"value":"Switzerland/ON595760/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Switzerland"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","T133101-","T133102-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"]}}},{"name":"OP324500","node_attrs":{"div":5,"accession":"OP324500","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0186/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP324500/2022-06-28"},"date":{"value":"2022-06-28"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C774-","G775-","C4592T","G11462A","G89734A","C92865T","C133750T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G192618A","T196649-","C196650-"],"OPG003":["E6K"],"OPG003_dup":["E6K"],"OPG023":["S480L"],"OPG110":["E35K"]},"labels":{"aa":"OPG003: E6K; OPG003_dup: E6K; OPG023: S480L; OPG110: E35K"}}},{"name":"OP324540","node_attrs":{"div":0,"accession":"OP324540","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0232/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP324540/2022-06-21"},"date":{"value":"2022-06-21"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","C146816T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A","-196616T"]}}},{"name":"OP324492","node_attrs":{"div":0,"accession":"OP324492","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0177/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP324492/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A","-196616T"]}}},{"name":"OP324497","node_attrs":{"div":0,"accession":"OP324497","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0182/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP324497/2022-06-27"},"date":{"value":"2022-06-27"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP324485","node_attrs":{"div":1,"accession":"OP324485","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0170/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP324485/2022-07-03"},"date":{"value":"2022-07-03"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179853T"]}}},{"name":"OP324475","node_attrs":{"div":1,"accession":"OP324475","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0158/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP324475/2022-07-07"},"date":{"value":"2022-07-07"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G727-","T728-","A136552-","T136553-","C136554-","G150394A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T196639-","T196640-"],"OPG153":["D385-"],"OPG176":["E196K"]},"labels":{"aa":"OPG153: D385-; OPG176: E196K"}}},{"name":"OP324472","node_attrs":{"div":1,"accession":"OP324472","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0155/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP324472/2022-07-06"},"date":{"value":"2022-07-06"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G685-","T686-","C21998T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196686-","T196687-"],"OPG037":["D146N"]},"labels":{"aa":"OPG037: D146N"}}},{"name":"OP310056","node_attrs":{"div":5,"accession":"OP310056","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-089437/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP310056/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C21398T","C66975T","C97153T","G120238A","C136972T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG037":["D346N"],"OPG085":["M519I"],"OPG137":["E213K"]},"labels":{"aa":"OPG037: D346N; OPG085: M519I; OPG137: E213K"}}},{"name":"OP245359","node_attrs":{"div":0,"accession":"OP245359","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/PT0126/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP245359/2022-07-14"},"date":{"value":"2022-07-14"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP245346","node_attrs":{"div":0,"accession":"OP245346","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/PT0112/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP245346/2022-07-15"},"date":{"value":"2022-07-15"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP245311","node_attrs":{"div":1,"accession":"OP245311","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/PT0055/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP245311/2022-07-28"},"date":{"value":"2022-07-28"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C136572T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G158190A"],"OPG153":["E366K"]},"labels":{"aa":"OPG153: E366K"}}},{"name":"OP245316","node_attrs":{"div":1,"accession":"OP245316","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/PT0062/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP245316/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C15652T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP245308","node_attrs":{"div":0,"accession":"OP245308","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/PT0051/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP245308/2022-07-31"},"date":{"value":"2022-07-31"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP215217","node_attrs":{"div":2,"accession":"OP215217","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI218"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP215217/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C56259T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C188946T"]}}},{"name":"OP205095","node_attrs":{"div":2,"accession":"OP205095","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000107"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205095/2022-06-13"},"date":{"value":"2022-06-13"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-607T","C49892T","A56110G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG074":["L339S"]},"labels":{"aa":"OPG074: L339S"}}},{"name":"OP205092","node_attrs":{"div":4,"accession":"OP205092","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000104"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205092/2022-06-12"},"date":{"value":"2022-06-12"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-607T","G30128T","C164096T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188683T","C190269T","-196615A"],"OPG047":["P356Q"],"OPG189":["S255L"]},"labels":{"aa":"OPG047: P356Q; OPG189: S255L"}}},{"name":"OP185715","node_attrs":{"div":1,"accession":"OP185715","author":{"author":"Gigante,C.M.,Steidley,B.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Davizon,E.S.,Li,Y.","value":"Gigante,C.M.,Steidley,B.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Davizon,E.S.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_CO0002"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP185715/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C17437T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG030":["E133K"]},"labels":{"aa":"OPG030: E133K"}}},{"name":"OP440563","node_attrs":{"div":1,"accession":"OP440563","author":{"author":"Hemarajata,P.,Green,N.M.","value":"Hemarajata,P.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00061/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP440563/2022-07-20"},"date":{"value":"2022-07-20"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C2489T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G194721A"],"OPG002":["G88E"],"OPG002_dup":["G88E"]},"labels":{"aa":"OPG002: G88E; OPG002_dup: G88E"}}},{"name":"OP415274","node_attrs":{"div":1,"accession":"OP415274","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_i96eY5_9000346"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415274/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G180299A"],"OPG208":["G345E"]},"labels":{"aa":"OPG208: G345E"}}},{"name":"OP415281","node_attrs":{"div":0,"accession":"OP415281","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_hSAaEl_9000356"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415281/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP422245","node_attrs":{"div":0,"accession":"OP422245","author":{"author":"Laubscher,F.,Chudzinsk,V.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinsk,V.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-CH-38212023/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"strain_display":{"value":"Switzerland/OP422245/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Switzerland"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OP415226","node_attrs":{"div":0,"accession":"OP415226","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_k9tr7U_9000256"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415226/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["A173518-","G173519-","A173520-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP415196","node_attrs":{"div":0,"accession":"OP415196","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_96X1Vd_9000218"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415196/2022-03-XX"},"date":{"value":"2022-03-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP415220","node_attrs":{"div":0,"accession":"OP415220","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_EduQvV_9000249"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415220/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP415194","node_attrs":{"div":0,"accession":"OP415194","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_96X1Vd_9000216"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415194/2022-03-XX"},"date":{"value":"2022-03-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP414372","node_attrs":{"div":0,"accession":"OP414372","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0343/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414372/2022-05-26"},"date":{"value":"2022-05-26"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP414365","node_attrs":{"div":1,"accession":"OP414365","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0335/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414365/2022-05-29"},"date":{"value":"2022-05-29"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C144555T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG166":["S53L"]},"labels":{"aa":"OPG166: S53L"}}},{"name":"OP414380","node_attrs":{"div":0,"accession":"OP414380","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0351/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414380/2022-05-24"},"date":{"value":"2022-05-24"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"]}}},{"name":"OP414330","node_attrs":{"div":2,"accession":"OP414330","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0296/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414330/2022-06-08"},"date":{"value":"2022-06-08"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C110108T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A152274G"]}}},{"name":"OP414300","node_attrs":{"div":3,"accession":"OP414300","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0259/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414300/2022-06-19"},"date":{"value":"2022-06-19"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-607T","C23759T","G68825A","G117941A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"]}}},{"name":"OP414323","node_attrs":{"div":3,"accession":"OP414323","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0288/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414323/2022-06-13"},"date":{"value":"2022-06-13"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-607T","G58696A","G59086A","G90052A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"],"OPG078":["S39L"],"OPG079":["S179L"],"OPG110":["D141N"]},"labels":{"aa":"OPG078: S39L; OPG079: S179L; OPG110: D141N"}}},{"name":"OP414301","node_attrs":{"div":1,"accession":"OP414301","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0261/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414301/2022-06-19"},"date":{"value":"2022-06-19"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C184822T"],"OPG210":["T1156I"]},"labels":{"aa":"OPG210: T1156I"}}},{"name":"OP414297","node_attrs":{"div":0,"accession":"OP414297","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0256/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414297/2022-06-19"},"date":{"value":"2022-06-19"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP414294","node_attrs":{"div":1,"accession":"OP414294","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0253/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414294/2022-06-21"},"date":{"value":"2022-06-21"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","G142942A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-"}}},{"name":"OP382494","node_attrs":{"div":0,"accession":"OP382494","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00017"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382494/2022-07-22"},"date":{"value":"2022-07-22"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP382491","node_attrs":{"div":4,"accession":"OP382491","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00014"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382491/2022-07-22"},"date":{"value":"2022-07-22"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["T606-","G5444A","C20105T","A83680T","G101344A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C191766T"],"OPG015":["S238L"],"OPG015_dup":["S238L"],"OPG105":["D852V"]},"labels":{"aa":"OPG015: S238L; OPG015_dup: S238L; OPG105: D852V"}}},{"name":"OP382490","node_attrs":{"div":0,"accession":"OP382490","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00013"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382490/2022-07-20"},"date":{"value":"2022-07-20"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP382487","node_attrs":{"div":0,"accession":"OP382487","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00010"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382487/2022-07-18"},"date":{"value":"2022-07-18"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OP382484","node_attrs":{"div":0,"accession":"OP382484","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00007"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382484/2022-07-06"},"date":{"value":"2022-07-06"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP382483","node_attrs":{"div":0,"accession":"OP382483","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00006"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382483/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OP382478","node_attrs":{"div":1,"accession":"OP382478","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382478/2022-06-13"},"date":{"value":"2022-06-13"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["C178006T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG205":["S784F"]},"labels":{"aa":"OPG205: S784F"}}},{"name":"OP555503","node_attrs":{"div":6,"accession":"OP555503","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0409/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555503/2022-07-25"},"date":{"value":"2022-07-25"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C15057T","G67261A","G74252A","G95760A","G118335A","G132631A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG025":["D71N"],"OPG085":["S424L"],"OPG094":["R158K"],"OPG116":["A134T"],"OPG136":["S418F"]},"labels":{"aa":"OPG025: D71N; OPG085: S424L; OPG094: R158K; OPG116: A134T; OPG136: S418F"}}},{"name":"OP555501","node_attrs":{"div":2,"accession":"OP555501","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0406/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555501/2022-07-20"},"date":{"value":"2022-07-20"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G11924A","G41652A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG023":["S326L"],"OPG061":["S78F"]},"labels":{"aa":"OPG023: S326L; OPG061: S78F"}}},{"name":"OP536815","node_attrs":{"div":0,"accession":"OP536815","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000453"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536815/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP536813","node_attrs":{"div":3,"accession":"OP536813","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000451"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536813/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","G61102A","C77309T","C96440T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A"],"OPG080":["S306F"],"OPG098":["S137L"],"OPG117":["T131I"]},"labels":{"aa":"OPG080: S306F; OPG098: S137L; OPG117: T131I"}}},{"name":"OP536811","node_attrs":{"div":2,"accession":"OP536811","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000448"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536811/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C95004T","G111541A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG130":["S121F"]},"labels":{"aa":"OPG130: S121F"}}},{"name":"OP539896","node_attrs":{"div":2,"accession":"OP539896","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00111/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP539896/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","C104164T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C177339T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T196813-","A196814-","A196815-"],"OPG123":["E303K"],"OPG205":["L562F"]},"labels":{"aa":"OPG123: E303K; OPG205: L562F"}}},{"name":"OP536802","node_attrs":{"div":2,"accession":"OP536802","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000430"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536802/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-607T","C87702T","G150484A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG176":["D226N"]},"labels":{"aa":"OPG176: D226N"}}},{"name":"OP536739","node_attrs":{"div":3,"accession":"OP536739","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-USA-IL-IDPH-078"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"strain_display":{"value":"USA/OP536739/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C88308T","G97290A","C109462T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"],"OPG129":["G515R"]},"labels":{"aa":"OPG129: G515R"}}},{"name":"OP536730","node_attrs":{"div":0,"accession":"OP536730","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-USA-IL-IDPH-069"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"strain_display":{"value":"USA/OP536730/2022-06-28"},"date":{"value":"2022-06-28"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"OP536682","node_attrs":{"div":1,"accession":"OP536682","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-USA-IL-IDPH-021"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"strain_display":{"value":"USA/OP536682/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C27368T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"OP524009","node_attrs":{"div":0,"accession":"OP524009","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI407"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP524009/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP523986","node_attrs":{"div":1,"accession":"OP523986","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI384"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP523986/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A4679T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T192531A"]}}},{"name":"OP484675","node_attrs":{"div":2,"accession":"OP484675","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI354"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP484675/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C87755T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G165247A"],"OPG109":["D565N"]},"labels":{"aa":"OPG109: D565N"}}},{"name":"OP484674","node_attrs":{"div":2,"accession":"OP484674","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI353"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP484674/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C32790T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C183220T"],"OPG049":["R121K"],"OPG210":["S622F"]},"labels":{"aa":"OPG049: R121K; OPG210: S622F"}}},{"name":"OP628484","node_attrs":{"div":3,"accession":"OP628484","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-088353/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP628484/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G44856T","C145137T","G162929A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG064":["P348H"],"OPG167":["D91N"],"OPG188":["R445K"]},"labels":{"aa":"OPG064: P348H; OPG167: D91N; OPG188: R445K"}}},{"name":"OP628489","node_attrs":{"div":4,"accession":"OP628489","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-092175/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP628489/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A93217G","G116130A","G151339A","G152202A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["K496R"]},"labels":{"aa":"OPG113: K496R"}}},{"name":"OP626127","node_attrs":{"div":1,"accession":"OP626127","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI489"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP626127/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C362T","C148390T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G196848A"],"OPG174":["E336K"]},"labels":{"aa":"OPG174: E336K"}}},{"name":"OP626117","node_attrs":{"div":3,"accession":"OP626117","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI479"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP626117/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C101074T","C128824T","G138682A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG150":["S349F"],"OPG156":["S243F"]},"labels":{"aa":"OPG150: S349F; OPG156: S243F"}}},{"name":"OP626105","node_attrs":{"div":1,"accession":"OP626105","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI467"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP626105/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C82676T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP605580","node_attrs":{"div":1,"accession":"OP605580","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-39-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605580/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["-607T","C179082T","C179091T","T179094A","C179100T","T179103A","C179109T","T179112A","C179118T","T179121A","C179127T","T179130A","C179136T","C179145T","T179148A","C179154T","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179239A","-179240T","-179241A","-179242T","-179243A","G189288A"]}}},{"name":"OP605573","node_attrs":{"div":0,"accession":"OP605573","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-31-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605573/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["-607T","A120644-","T120645-","T120646-","A120647-","G120648-","T120649-","G120650-","G120651-","G120652-","C120653-","A120654-","T120655-","C120656-","T120657-","T120658-","T120659-","T120660-","T120661-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179216A","-179217C","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG138":["M160-","P161-","T162-","N163-","K164-","K165-"]},"labels":{"aa":"OPG138: M160-, P161-, T162-, N163-, K164-, K165-"}}},{"name":"OP605575","node_attrs":{"div":0,"accession":"OP605575","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-33-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605575/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["-607T","C179154T","T179157A","C179163T","T179166A","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181T","-179182A","-179183T","-179184A","-179185A","-179186T","-179187A","-179188T","-179189A","-179190T","-179191A","-179192T","-179193A","-179194A","-179195T","-179196A","-179197T","-179198A","-179204T","-179205A","-179206T","-179207A","-179208T","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP605571","node_attrs":{"div":2,"accession":"OP605571","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-29-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605571/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["T264-","-607T","A86557T","A120644-","T120645-","T120646-","A120647-","G120648-","T120649-","G120650-","G120651-","G120652-","C120653-","A120654-","T120655-","C120656-","T120657-","T120658-","T120659-","T120660-","T120661-","C168661T","G173318A","G173319T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG108":["I168K"],"OPG138":["M160-","P161-","T162-","N163-","K164-","K165-"]},"labels":{"aa":"OPG108: I168K; OPG138: M160-, P161-, T162-, N163-, K164-, K165-"}}},{"name":"OP605582","node_attrs":{"div":10,"accession":"OP605582","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-41-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605582/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["C198-","-607T","C27187T","G176523A","C176524T","T176532G","G176536C","A176544T","A176550T","A176551G","T176552C","A176559C","T179059G","T179072A","G179076T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG043":["D257N"],"OPG205":["A290Y","I297L","N299C"]},"labels":{"aa":"OPG043: D257N; OPG205: A290Y, I297L, N299C"}}},{"name":"OP605569","node_attrs":{"div":2,"accession":"OP605569","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-27-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605569/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["-607T","G104565A","G130432A","T179166A","-179172C","-179173A","-179174G","-179175T","-179176A","-179177T","-179178C","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185G","-179186T","-179187T","-179188T","-179189A","-179190G","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197A","-179198T","-179199C","-179200C","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208A","-179209T","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217T","-179218A","-179219T","-179220C","-179221A","-179222T","-179223A","-179224T","-179225C","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236T","-179237T","-179238T","-179239A","-179240C","-179241A","-179242T","-179243A","T179248A","T179254A","G179256C","T179258G","A179261T","G179269A","T179271C","A179272G"],"OPG123":["S169F"],"OPG208":["D2N","I3V"]},"labels":{"aa":"OPG123: S169F; OPG208: D2N, I3V"}}},{"name":"OP605563","node_attrs":{"div":1,"accession":"OP605563","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-21-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605563/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","A29748T"],"OPG047":["*483K"]},"labels":{"aa":"OPG047: *483K"}}},{"name":"OP605561","node_attrs":{"div":0,"accession":"OP605561","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-19-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605561/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{}}},{"name":"OP605558","node_attrs":{"div":0,"accession":"OP605558","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-16-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605558/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP605554","node_attrs":{"div":0,"accession":"OP605554","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-11-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605554/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{}}},{"name":"OP603007","node_attrs":{"div":1,"accession":"OP603007","author":{"author":"Gigante,C.M.,Xia,D.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y.","value":"Gigante,C.M.,Xia,D.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_PA0007"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP603007/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","A153679T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-196615A"],"OPG180":["T330S"]},"labels":{"aa":"OPG180: T330S"}}},{"name":"OP555657","node_attrs":{"div":2,"accession":"OP555657","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0589/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555657/2022-08-24"},"date":{"value":"2022-08-24"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-607T","G2543A","G73164A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C194667T","-196615A"],"OPG002":["S70L"],"OPG002_dup":["S70L"],"OPG093":["E63K"]},"labels":{"aa":"OPG002: S70L; OPG002_dup: S70L; OPG093: E63K"}}},{"name":"OP555648","node_attrs":{"div":4,"accession":"OP555648","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0577/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555648/2022-09-09"},"date":{"value":"2022-09-09"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G2360A","A136552-","T136553-","C136554-","G146433A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C167425T","C189174T","C194850T"],"OPG002":["T131I"],"OPG002_dup":["T131I"],"OPG153":["D385-"],"OPG170":["H116Y"],"OPG193":["S31F"]},"labels":{"aa":"OPG002: T131I; OPG002_dup: T131I; OPG153: D385-; OPG170: H116Y; OPG193: S31F"}}},{"name":"OP555647","node_attrs":{"div":7,"accession":"OP555647","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0576/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555647/2022-09-05"},"date":{"value":"2022-09-05"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C28104T","C28175T","C46132T","G112246A","C125152T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A153083G","C162012T"],"OPG044":["S5L"],"OPG065":["D118N"],"OPG131":["D103N"],"OPG180":["K131R"]},"labels":{"aa":"OPG044: S5L; OPG065: D118N; OPG131: D103N; OPG180: K131R"}}},{"name":"OP555610","node_attrs":{"div":0,"accession":"OP555610","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0539/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555610/2022-08-23"},"date":{"value":"2022-08-23"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-607T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"]}}},{"name":"OP555612","node_attrs":{"div":3,"accession":"OP555612","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0541/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555612/2022-08-23"},"date":{"value":"2022-08-23"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G98166A","C124265T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C157632T"]}}},{"name":"OP555578","node_attrs":{"div":3,"accession":"OP555578","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0504/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555578/2022-08-13"},"date":{"value":"2022-08-13"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G70841A","G132625A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G182189A"],"OPG089":["E326K"]},"labels":{"aa":"OPG089: E326K"}}},{"name":"OP837355","node_attrs":{"div":0,"accession":"OP837355","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI593"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP837355/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP747062","node_attrs":{"div":3,"accession":"OP747062","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-106624/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP747062/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C90945T","C103417T","C173114T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG123":["E552K"]},"labels":{"aa":"OPG123: E552K"}}},{"name":"OP743991","node_attrs":{"div":0,"accession":"OP743991","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-092990/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP743991/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP748946","node_attrs":{"div":1,"accession":"OP748946","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00260/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP748946/2022-10-17"},"date":{"value":"2022-10-17"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C12684T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG023":["E73K"]},"labels":{"aa":"OPG023: E73K"}}},{"name":"OP743357","node_attrs":{"div":0,"accession":"OP743357","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200022/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Utah Public Health Laboratory"},"strain_display":{"value":"USA/OP743357/2022-05-21"},"date":{"value":"2022-05-21"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OP743358","node_attrs":{"div":0,"accession":"OP743358","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200023/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Utah Public Health Laboratory"},"strain_display":{"value":"USA/OP743358/2022-05-21"},"date":{"value":"2022-05-21"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OP743365","node_attrs":{"div":3,"accession":"OP743365","author":{"author":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J.","value":"Iverson,T.,Oakeson,K.F.,Young,E.L.,Wagner,J.,Hergert,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/UT-UPHL-82200134/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Utah Public Health Laboratory"},"strain_display":{"value":"USA/OP743365/2022-07-27"},"date":{"value":"2022-07-27"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","C138921A","A149457T","C189536T"],"OPG005":["S113L"],"OPG153":["D385-"],"OPG175":["I6L"]},"labels":{"aa":"OPG005: S113L; OPG153: D385-; OPG175: I6L"}}},{"name":"OP715826","node_attrs":{"div":0,"accession":"OP715826","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI546"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP715826/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OP693649","node_attrs":{"div":2,"accession":"OP693649","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT_INS_MPX_0039_L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP693649/2022-07-29"},"date":{"value":"2022-07-29"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A2840-","T2841-","C2842-","G127058A","G136194A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","T196865-","A196866-","G196867-"],"OPG148":["R358K"],"OPG153":["H492Y"]},"labels":{"aa":"OPG148: R358K; OPG153: H492Y"}}},{"name":"OP689665","node_attrs":{"div":0,"accession":"OP689665","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI512"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP689665/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OQ319136","node_attrs":{"div":0,"accession":"OQ319136","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI678"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ319136/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150564-","G150565-","A150566-","T150567-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OQ099609","node_attrs":{"div":1,"accession":"OQ099609","author":{"author":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_IL0031"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ099609/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G50617A","A173314-","T173315-","A173316-","T173317-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A"],"OPG070":["D10N"]},"labels":{"aa":"OPG070: D10N"}}},{"name":"OP920685","node_attrs":{"div":9,"accession":"OP920685","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00347/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP920685/2022-10-09"},"date":{"value":"2022-10-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C29308T","C54262T","C65348T","G69678A","G74672A","C76556T","C105161T","C144237T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G162016A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG046":["G141E"],"OPG094":["R298K"],"OPG097":["R107K"],"OPG124":["D270N"],"OPG165":["S241L"],"OPG188":["E141K"]},"labels":{"aa":"OPG046: G141E; OPG094: R298K; OPG097: R107K; OPG124: D270N; OPG165: S241L; OPG188: E141K"}}},{"name":"OP920696","node_attrs":{"div":3,"accession":"OP920696","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00358/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP920696/2022-11-05"},"date":{"value":"2022-11-05"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G15683A","C104028T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G184416A"],"OPG123":["G348E"],"OPG210":["D1021N"]},"labels":{"aa":"OPG123: G348E; OPG210: D1021N"}}},{"name":"OP935995","node_attrs":{"div":2,"accession":"OP935995","author":{"author":"Bajwa,M.I.,Miller,H.","value":"Bajwa,M.I.,Miller,H."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"B1118436"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Delaware Public Health Lab, Sequencing/Bioinformatics"},"strain_display":{"value":"USA/OP935995/2022-10-02"},"date":{"value":"2022-10-02"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C95099T","C135868T","A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG115":["S147L"],"OPG153":["D385-"]},"labels":{"aa":"OPG115: S147L; OPG153: D385-"}}},{"name":"OQ411312","node_attrs":{"div":1,"accession":"OQ411312","author":{"author":"Laubscher,F.,Chudzinsk,V.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Chudzinsk,V.,Schibler,M.,Kaiser,L.,Renzoni,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-CH-38292866/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"strain_display":{"value":"Switzerland/OQ411312/2022-06-08"},"date":{"value":"2022-06-08"},"country":{"value":"Switzerland"}},"branch_attrs":{"mutations":{"nuc":["C87764T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG109":["E562K"]},"labels":{"aa":"OPG109: E562K"}}},{"name":"OQ348875","node_attrs":{"div":3,"accession":"OQ348875","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000128/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDPH, VRDL"},"strain_display":{"value":"USA/OQ348875/2022-06-27"},"date":{"value":"2022-06-27"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T6976-","G53144A","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","C145153T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C165730T","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG071":["S432F"]},"labels":{"aa":"OPG071: S432F"}}},{"name":"OQ339209","node_attrs":{"div":2,"accession":"OQ339209","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI690"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ339209/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","G103240A","G150551-","A150563-","T150564-","G150565-","A150566-","T150567-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C156437T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG044":["K147-"]},"labels":{"aa":"OPG044: K147-"}}},{"name":"OQ320520","node_attrs":{"div":0,"accession":"OQ320520","author":{"author":"Gigante,C.,Ostadkar,R.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Weigand,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,X.,Li,Y.","value":"Gigante,C.,Ostadkar,R.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Weigand,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,X.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_MN0008"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ320520/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ320449","node_attrs":{"div":3,"accession":"OQ320449","author":{"author":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y.","value":"Gigante,C.,Hauser,J.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mangla,A.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_DC0020"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ320449/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G6619A","C99831T","C142957T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ557951","node_attrs":{"div":5,"accession":"OQ557951","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_TX0003"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ557951/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","C19610T","G108050A","T133102-","C135024T","C135225T","C156627T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-196615A"]}}},{"name":"OQ547776","node_attrs":{"div":0,"accession":"OQ547776","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI749"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ547776/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OQ547894","node_attrs":{"div":0,"accession":"OQ547894","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000169/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDPH, VRDL"},"strain_display":{"value":"USA/OQ547894/2023-01-09"},"date":{"value":"2023-01-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T6976-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OQ503763","node_attrs":{"div":1,"accession":"OQ503763","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-090794/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OQ503763/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G72069A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR086938","node_attrs":{"div":0,"accession":"OR086938","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Horemans,M.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Horemans,M.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_129/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR086938/2022-06-29"},"date":{"value":"2022-06-29"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035730","node_attrs":{"div":4,"accession":"OR035730","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_124"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035730/2022-09-20"},"date":{"value":"2022-09-20"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C12298T","C32853T","G35385A","C169036T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG049":["G100E"]},"labels":{"aa":"OPG049: G100E"}}},{"name":"OR035729","node_attrs":{"div":2,"accession":"OR035729","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_123"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035729/2022-09-20"},"date":{"value":"2022-09-20"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C19277T","C166803T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG192":["P25S"]},"labels":{"aa":"OPG192: P25S"}}},{"name":"OR035725","node_attrs":{"div":1,"accession":"OR035725","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_119"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035725/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-","C137999T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG154":["E18K"]},"labels":{"aa":"OPG154: E18K"}}},{"name":"OR035720","node_attrs":{"div":1,"accession":"OR035720","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_114"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035720/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C8597T","T133101-","T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035693","node_attrs":{"div":0,"accession":"OR035693","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_87"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035693/2022-08-09"},"date":{"value":"2022-08-09"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035687","node_attrs":{"div":1,"accession":"OR035687","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_81"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035687/2022-08-09"},"date":{"value":"2022-08-09"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T98627C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG118":["V61A"]},"labels":{"aa":"OPG118: V61A"}}},{"name":"OR035684","node_attrs":{"div":0,"accession":"OR035684","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_78"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035684/2022-06-29"},"date":{"value":"2022-06-29"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035681","node_attrs":{"div":0,"accession":"OR035681","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_75"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035681/2022-06-03"},"date":{"value":"2022-06-03"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-"]}}},{"name":"OR035682","node_attrs":{"div":0,"accession":"OR035682","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_76"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035682/2022-06-07"},"date":{"value":"2022-06-07"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035683","node_attrs":{"div":0,"accession":"OR035683","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_77"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035683/2022-06-13"},"date":{"value":"2022-06-13"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035656","node_attrs":{"div":1,"accession":"OR035656","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_50"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035656/2022-05-31"},"date":{"value":"2022-05-31"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","C173614T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035649","node_attrs":{"div":0,"accession":"OR035649","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_43"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035649/2022-08-02"},"date":{"value":"2022-08-02"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR030940","node_attrs":{"div":1,"accession":"OR030940","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_29"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR030940/2022-07-15"},"date":{"value":"2022-07-15"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C82511T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR030935","node_attrs":{"div":2,"accession":"OR030935","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_24"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR030935/2022-07-19"},"date":{"value":"2022-07-19"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C94839T","C131367T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG151":["S815F"]},"labels":{"aa":"OPG151: S815F"}}},{"name":"OR030933","node_attrs":{"div":1,"accession":"OR030933","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_22"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR030933/2022-07-19"},"date":{"value":"2022-07-19"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","C170121T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR030925","node_attrs":{"div":1,"accession":"OR030925","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_7"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR030925/2022-06-09"},"date":{"value":"2022-06-09"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["A28532-","T76087-","T80849-","T133639-","A138474-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C187959T","-196615A"],"OPG044":["M148-"]},"labels":{"aa":"OPG044: M148-"}}},{"name":"OR030923","node_attrs":{"div":0,"accession":"OR030923","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_12"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR030923/2022-06-29"},"date":{"value":"2022-06-29"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T606-","A26090-","T26091-","T76087-","T80849-","A89106-","T133101-","T133102-","T155424-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OQ918696","node_attrs":{"div":6,"accession":"OQ918696","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00485/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ918696/2023-03-11"},"date":{"value":"2023-03-11"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G30285A","G37487A","C71193T","G119839A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C161690T","C177865T","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T179244-"],"OPG047":["P304S"],"OPG137":["E80K"],"OPG188":["S32F"],"OPG205":["S737F"]},"labels":{"aa":"OPG047: P304S; OPG137: E80K; OPG188: S32F; OPG205: S737F"}}},{"name":"OQ721951","node_attrs":{"div":3,"accession":"OQ721951","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Taiwan/110-122438/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"strain_display":{"value":"Taiwan/OQ721951/2023-03-XX"},"date":{"value":"2023-03-XX"},"country":{"value":"Taiwan"}},"branch_attrs":{"mutations":{"nuc":["T133092-","T133093-","T133094-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T149983A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G160358A","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A184479G","G193496T","A193498T","A193748G","T194019G","T194021A","G194086A"],"OPG003_dup":["K298N","E299V","C473G","R495K"],"OPG176":["S59T"],"OPG210":["R1042G"]},"labels":{"aa":"OPG003_dup: K298N, E299V, C473G, R495K; OPG176: S59T; OPG210: R1042G"}}},{"name":"OQ672580","node_attrs":{"div":9,"accession":"OQ672580","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Taiwan/110-093354/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"strain_display":{"value":"Taiwan/OQ672580/2023-03-XX"},"date":{"value":"2023-03-XX"},"country":{"value":"Taiwan"}},"branch_attrs":{"mutations":{"nuc":["T4795C","C39503G","G43620A","A44076G","G45563A","T69121C","T80764C","A130204G","A143123G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG057":["K231N"],"OPG064":["F608S"],"OPG087":["Y89H"],"OPG104":["N86D"],"OPG164":["T116A"]},"labels":{"aa":"OPG057: K231N; OPG064: F608S; OPG087: Y89H; OPG104: N86D; OPG164: T116A"}}},{"name":"OQ627926","node_attrs":{"div":0,"accession":"OQ627926","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"INMI-22932022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"strain_display":{"value":"Italy/OQ627926/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OQ581849","node_attrs":{"div":2,"accession":"OQ581849","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0007b/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"strain_display":{"value":"Spain/OQ581849/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["A52777C","C150418T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T169409C","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG071":["Y554*"]},"labels":{"aa":"OPG071: Y554*"}}},{"name":"OQ581848","node_attrs":{"div":1,"accession":"OQ581848","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0006b/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"strain_display":{"value":"Spain/OQ581848/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["C133168-","T133169-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C174264T","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ570421","node_attrs":{"div":2,"accession":"OQ570421","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"INMI-22872022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"strain_display":{"value":"Italy/OQ570421/2022-08-22"},"date":{"value":"2022-08-22"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["C106275T","G111562A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG130":["S114F"]},"labels":{"aa":"OPG130: S114F"}}},{"name":"OR449703","node_attrs":{"div":0,"accession":"OR449703","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI989"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR449703/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"OR449638","node_attrs":{"div":0,"accession":"OR449638","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI924"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR449638/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150551-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"OR353584","node_attrs":{"div":1,"accession":"OR353584","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MN-MDH-MPXV_0074"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Minnesota Department of Health, Public Health Laboratory"},"strain_display":{"value":"USA/OR353584/2022-09-15"},"date":{"value":"2022-09-15"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","T129642G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T196756-","G196757-","T196758-"],"OPG151":["L240*"]},"labels":{"aa":"OPG151: L240*"}}},{"name":"OR264462","node_attrs":{"div":0,"accession":"OR264462","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"8_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264462/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OR264461","node_attrs":{"div":0,"accession":"OR264461","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"8_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264461/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264418","node_attrs":{"div":0,"accession":"OR264418","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"44_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264418/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OR264419","node_attrs":{"div":0,"accession":"OR264419","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"44_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264419/2022-07-10"},"date":{"value":"2022-07-10"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OR264409","node_attrs":{"div":1,"accession":"OR264409","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"39_L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264409/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["C66718T","T179244-"],"OPG084":["S666L"]},"labels":{"aa":"OPG084: S666L"}}},{"name":"OR264387","node_attrs":{"div":0,"accession":"OR264387","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"28_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264387/2022-06-23"},"date":{"value":"2022-06-23"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264384","node_attrs":{"div":6,"accession":"OR264384","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"27_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264384/2022-08-14"},"date":{"value":"2022-08-14"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","G29641A","A50415G","T76084-","T76085-","T80846-","T80847-","G109811A","T121121-","C146721T","A152675-","A152676-","G176229A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","G188299A"],"OPG044":["K147-"],"OPG046":["S30L"],"OPG069":["S144G"],"OPG170":["E20K"],"OPG205":["E192K"]},"labels":{"aa":"OPG044: K147-; OPG046: S30L; OPG069: S144G; OPG170: E20K; OPG205: E192K"}}},{"name":"OR095066","node_attrs":{"div":0,"accession":"OR095066","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_248/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR095066/2022-08-16"},"date":{"value":"2022-08-16"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR086978","node_attrs":{"div":0,"accession":"OR086978","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_169/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR086978/2022-07-27"},"date":{"value":"2022-07-27"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR086963","node_attrs":{"div":0,"accession":"OR086963","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_154/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR086963/2022-07-15"},"date":{"value":"2022-07-15"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR086969","node_attrs":{"div":0,"accession":"OR086969","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_160/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR086969/2022-07-27"},"date":{"value":"2022-07-27"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C196750-","T196751-","A196752-"]}}},{"name":"OR086948","node_attrs":{"div":0,"accession":"OR086948","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_139/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR086948/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OX336004","node_attrs":{"div":1,"accession":"OX336004","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX336004/2022-08-26"},"date":{"value":"2022-08-26"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{"nuc":["T606-","C94836T","T133100-","T133101-","T133102-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"]}}},{"name":"OX261748","node_attrs":{"div":0,"accession":"OX261748","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX261748/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{"nuc":["T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"]}}},{"name":"OR759206","node_attrs":{"div":4,"accession":"OR759206","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL118/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759206/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["T606-","C25172T","C67289T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G164327A","G164910A","A196614-"],"OPG040":["D103N"],"OPG085":["E415K"],"OPG189":["G332E"]},"labels":{"aa":"OPG040: D103N; OPG085: E415K; OPG189: G332E"}}},{"name":"OR759163","node_attrs":{"div":0,"accession":"OR759163","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL072/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759163/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR759159","node_attrs":{"div":1,"accession":"OR759159","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL071/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759159/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C20143T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG035":["E88K"]},"labels":{"aa":"OPG035: E88K"}}},{"name":"OR759145","node_attrs":{"div":1,"accession":"OR759145","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL054/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759145/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C171732T"],"OPG199":["L249F"]},"labels":{"aa":"OPG199: L249F"}}},{"name":"OR499950","node_attrs":{"div":8,"accession":"OR499950","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00493/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499950/2023-04-24"},"date":{"value":"2023-04-24"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C21494T","C69560T","C80874T","C86342T","C137855T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C182578T","C188161T","C189998T"],"OPG037":["D314N"],"OPG088":["V102M"],"OPG104":["S49N"],"OPG108":["D240N"],"OPG154":["E66K"],"OPG210":["S408L"]},"labels":{"aa":"OPG037: D314N; OPG088: V102M; OPG104: S49N; OPG108: D240N; OPG154: E66K; OPG210: S408L"}}},{"name":"OR488002","node_attrs":{"div":2,"accession":"OR488002","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0684/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR488002/2022-05-31"},"date":{"value":"2022-05-31"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C132153T","C132940T","C133227T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG151":["S1077L"]},"labels":{"aa":"OPG151: S1077L"}}},{"name":"OR464218","node_attrs":{"div":2,"accession":"OR464218","author":{"author":"Gigante,C.,Johnson,S.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Riner,D.,Li,Y.","value":"Gigante,C.,Johnson,S.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Riner,D.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_MI0013"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OR464218/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C8222T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","G186177A"],"OPG210":["E1608K"]},"labels":{"aa":"OPG210: E1608K"}}},{"name":"OR464192","node_attrs":{"div":6,"accession":"OR464192","author":{"author":"Gigante,C.,Pettit,D.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Deutsch-Feldman,M.,Li,Y.","value":"Gigante,C.,Pettit,D.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Deutsch-Feldman,M.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_NC0016"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OR464192/2022-12-XX"},"date":{"value":"2022-12-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T606-","C14091T","G16956A","G56721A","C94427T","G141759A","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","C184829T","A196614-"],"OPG025":["E393K"],"OPG114":["E81K"]},"labels":{"aa":"OPG025: E393K; OPG114: E81K"}}},{"name":"NODE_0000042","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C127220T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG148":["S412L"],"OPG149":["Q9*"]},"labels":{"aa":"OPG148: S412L; OPG149: Q9*"}},"children":[{"name":"ON585036","node_attrs":{"div":2,"accession":"ON585036","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Ferreira,R.,Sobral,D.,Nunes,A.,Santos,J.D.,Mixao,V.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0010/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"strain_display":{"value":"Portugal/ON585036/2022-05-15"},"date":{"value":"2022-05-15"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C144527T","A188351-"],"OPG166":["P44S"]},"labels":{"aa":"OPG166: P44S"}}},{"name":"OP414370","node_attrs":{"div":1,"accession":"OP414370","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0341/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414370/2022-05-27"},"date":{"value":"2022-05-27"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C663-","A664-","A196619-","T196620-"]}}}]},{"name":"NODE_0000043","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133102-","T168120C","-179207A"],"OPG193":["F263L"]},"labels":{"aa":"OPG193: F263L"}},"children":[{"name":"OP144216","node_attrs":{"div":1,"accession":"OP144216","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/ITM_pt_07/Belgium/30-May-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OP144216/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["A133165-","A133166-","T133167-","C133168-","T133169-","T133170-","T133171-","C133172-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T140113-","A140114-","T140115-","A140116-","A140117-","T140122-","A140123-","T140124-","A140125-","A140126-","C140127-","A140128-","A140129-","T140130-","T140131-","A140132-","T140133-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","A140143-","A140144-","T140145-","T140146-","G140147-","T140148-","T140149-","A140150-","T140151-","A140152-","A140153-","T140154-","A140155-","-179240T","-179241A","-179242T","-179243A"],"OPG159":["Y116-","N117-","Y119-","N120-","N121-","Y122-","N123-","N124-","Y125-","N126-","C127-","Y128-","N129-","N130-"]},"labels":{"aa":"OPG159: Y116-, N117-, Y119-, N120-, N121-, Y122-, N123-, N124-, Y125-, N126-, C127-, Y128-, N129-, N130-"}}},{"name":"OP144215","node_attrs":{"div":1,"accession":"OP144215","author":{"author":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P.","value":"De Baetselier,I.,Van Dijck,C.,Kenyon,C.,Coppens,J.,Smet,H.,de Block,T.,Coppens,S.,Vanroye,F.,Bugert,J.,Girl,P.,Liesenborghs,L.,Selhorst,P.,Arien,K.,den Bossche,D.V.,Florence,E.,Rezende,A.M.,Vercauteren,K.,Esbroeck,M.V.,Bracke,S.,Brosius,I.,Soentjens,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/ITM_pt_05/Belgium/30-May-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OP144215/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T179244-","C179245-","G179246-","T179247-","T179248-"]}}}]},{"name":"NODE_0000044","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A28532-","T133098-","T133099-","T133100-","T133101-","T133102-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","C179091-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188252T","A196613-","A196614-"],"OPG044":["M148-"]},"labels":{"aa":"OPG044: M148-"}},"children":[{"name":"OP133005","node_attrs":{"div":1,"accession":"OP133005","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1531848/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP133005/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{"nuc":["A179077-","A179090-","A179092-","T179093-","G197058T","C197173G"]}}},{"name":"OP133004","node_attrs":{"div":1,"accession":"OP133004","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1533374/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP133004/2022-07-11"},"date":{"value":"2022-07-11"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{"nuc":["A322G","T450C","-179091T"]}}}]},{"name":"NODE_0000045","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C144546T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-196615A"],"OPG166":["S50F"]},"labels":{"aa":"OPG166: S50F"}},"children":[{"name":"OP019275","node_attrs":{"div":3,"accession":"OP019275","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1525179/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP019275/2022-06-10"},"date":{"value":"2022-06-10"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{"nuc":["-608T","-609T","A107070C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G190319A","-196616A","-196617A"]}}},{"name":"OR473631","node_attrs":{"div":1,"accession":"OR473631","author":{"author":"Kwasiborski,A.,Hourdel,V.,Baliere,C.,Hoinard,D.,Grassin,Q.,Feher,M.,De La Porte Des Vaux,C.,Cresta,M.,Vanhomwegen,J.,Manuguerra,J.-C.,Batejat,C.,Caro,V.","value":"Kwasiborski,A.,Hourdel,V.,Baliere,C.,Hoinard,D.,Grassin,Q.,Feher,M.,De La Porte Des Vaux,C.,Cresta,M.,Vanhomwegen,J.,Manuguerra,J.-C.,Batejat,C.,Caro,V."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"CIBU-220031"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Insitut Pasteur, Environment and Infectious Risks Unit"},"strain_display":{"value":"France/OR473631/2022-06-03"},"date":{"value":"2022-06-03"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A"]}}}]},{"name":"NODE_0000046","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C4629T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","G192581A"]}},"children":[{"name":"ON622713","node_attrs":{"div":1,"accession":"ON622713","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/UZ_REGA_2/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Microbiology, Immunology & Transplantation, KU Leuven, Rega Institute, Belgium"},"strain_display":{"value":"Belgium/ON622713/2022-05-22"},"date":{"value":"2022-05-22"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ159044","node_attrs":{"div":6,"accession":"OQ159044","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI649"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ159044/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C75807T","C110546T","G141123A","G157626A","C171794T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG096":["A74V"],"OPG161":["E8K"]},"labels":{"aa":"OPG096: A74V; OPG161: E8K"}}}]},{"name":"NODE_0000047","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C96773T","C109432T","C142356T"],"OPG117":["S242L"],"OPG129":["D525N"],"OPG163":["S52F"]},"labels":{"aa":"OPG117: S242L; OPG129: D525N; OPG163: S52F"}},"children":[{"name":"OP341487","node_attrs":{"div":4,"accession":"OP341487","author":{"author":"Welkers,M.,Jonges,M.,de Regt,M.,Ooijevaar,R.,Wagemakers,A.","value":"Welkers,M.,Jonges,M.,de Regt,M.,Ooijevaar,R.,Wagemakers,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Netherlands/NH-AUMC-0060/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Amsterdam Medical Centres location AMC, Medical Microbiology & Infection Prevention"},"strain_display":{"value":"Netherlands/OP341487/2022-08-05"},"date":{"value":"2022-08-05"},"country":{"value":"Netherlands"}},"branch_attrs":{"mutations":{"nuc":["C114985T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG133":["D238N"]},"labels":{"aa":"OPG133: D238N"}}},{"name":"OP245310","node_attrs":{"div":3,"accession":"OP245310","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/PT0053/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP245310/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}}]},{"name":"NODE_0000048","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G16110A","G51378A","C89030T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G181082A"],"OPG109":["V140I"],"OPG209":["D189N"]},"labels":{"aa":"OPG109: V140I; OPG209: D189N"}},"children":[{"name":"OP328312","node_attrs":{"div":4,"accession":"OP328312","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-087564/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP328312/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR433615","node_attrs":{"div":4,"accession":"OR433615","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-080214/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR433615/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000049","node_attrs":{"div":1,"lineage":{"value":"B.1.13"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G175093A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG204":["D188N"]},"labels":{"aa":"OPG204: D188N","clade":"B.1.13"}},"children":[{"name":"OP257254","node_attrs":{"div":2,"accession":"OP257254","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.13"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/OH-UW-073812/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP257254/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C132520T"]}}},{"name":"OP536663","node_attrs":{"div":3,"accession":"OP536663","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"lineage":{"value":"B.1.13"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-USA-IL-IDPH-002"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"strain_display":{"value":"USA/OP536663/2022-08-04"},"date":{"value":"2022-08-04"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G119424A","G125452A","-196615A","-196616A","-196617A"],"OPG136":["S55L"],"OPG146":["S63L"]},"labels":{"aa":"OPG136: S55L; OPG146: S63L"}}}]},{"name":"NODE_0000050","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C23567T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OP205109","node_attrs":{"div":2,"accession":"OP205109","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000146"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205109/2022-06-13"},"date":{"value":"2022-06-13"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C118683T"],"OPG136":["R302K"]},"labels":{"aa":"OPG136: R302K"}}},{"name":"OP415212","node_attrs":{"div":4,"accession":"OP415212","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_UbfBKN_9000238"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415212/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C67289T","G67527A","G77052A"],"OPG085":["E415K"]},"labels":{"aa":"OPG085: E415K"}}}]},{"name":"NODE_0000051","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C102355T","C113923T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG121":["S189L"],"OPG133":["D592N"]},"labels":{"aa":"OPG121: S189L; OPG133: D592N"}},"children":[{"name":"OP422343","node_attrs":{"div":2,"accession":"OP422343","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1540386/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP422343/2022-08-08"},"date":{"value":"2022-08-08"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{}}},{"name":"OP422340","node_attrs":{"div":2,"accession":"OP422340","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1533948/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP422340/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000052","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T12827C","T12833A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG023":["D23V","N25S"]},"labels":{"aa":"OPG023: D23V, N25S"}},"children":[{"name":"OP440550","node_attrs":{"div":4,"accession":"OP440550","author":{"author":"Hemarajata,P.,Green,N.M.","value":"Hemarajata,P.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00035/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP440550/2022-08-13"},"date":{"value":"2022-08-13"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C1735T","T149447C","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G195475A","-196615A"]}}},{"name":"OP414329","node_attrs":{"div":3,"accession":"OP414329","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0295/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414329/2022-06-08"},"date":{"value":"2022-06-08"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C27303T"],"OPG043":["G218E"]},"labels":{"aa":"OPG043: G218E"}}}]},{"name":"NODE_0000053","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C170573T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}},"children":[{"name":"OP415248","node_attrs":{"div":3,"accession":"OP415248","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_XJRG9b_9000293"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415248/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["G148403A","G148615A"],"OPG174":["L261F"]},"labels":{"aa":"OPG174: L261F"}}},{"name":"OP605567","node_attrs":{"div":3,"accession":"OP605567","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-25-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605567/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["C71938T","G73939A","T196886-","T196887-","T196888-"],"OPG092":["R337K"],"OPG094":["D54N"]},"labels":{"aa":"OPG092: R337K; OPG094: D54N"}}}]},{"name":"NODE_0000054","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G59905A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG080":["S705F"]},"labels":{"aa":"OPG080: S705F"}},"children":[{"name":"OP615276","node_attrs":{"div":4,"accession":"OP615276","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00203/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP615276/2022-07-19"},"date":{"value":"2022-07-19"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G131350A","C135330T","G150732A"]}}},{"name":"OP722497","node_attrs":{"div":2,"accession":"OP722497","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00238/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP722497/2022-07-21"},"date":{"value":"2022-07-21"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C165424T"]}}}]},{"name":"NODE_0000055","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A33-","C8385T","A86934G","G91904A","T133101-","T133102-","A151508-","A151509-","T151510-","T151512-","T151514-","T151517-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196751-","A196752-"]}},"children":[{"name":"OP605584","node_attrs":{"div":4,"accession":"OP605584","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-43-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605584/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["-607T","T33995A","-133101T","-133102T","-151508A","-151509A","-151510T","-151512T","-151514T","-151517T","-151523A","-151524T","-196751T","-196752A"],"OPG052":["M1L"]},"labels":{"aa":"OPG052: M1L"}}},{"name":"OR087013","node_attrs":{"div":3,"accession":"OR087013","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_204/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR087013/2022-08-08"},"date":{"value":"2022-08-08"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G151511-","C151513-","C151515-","G151516-","G151518-","G151519-","G151520-","G151521-","C151522-","C196750-"]}}}]},{"name":"NODE_0000056","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G84579A","A87268G","G115865A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG105":["D1152N"],"OPG109":["V727A"],"OPG134":["R39K"]},"labels":{"aa":"OPG105: D1152N; OPG109: V727A; OPG134: R39K"}},"children":[{"name":"OP588277","node_attrs":{"div":3,"accession":"OP588277","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI414"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP588277/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-179189A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"]}}},{"name":"OP689663","node_attrs":{"div":3,"accession":"OP689663","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI510"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP689663/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000057","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C55859T","C93755T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG074":["V423I"]},"labels":{"aa":"OPG074: V423I"}},"children":[{"name":"OP555660","node_attrs":{"div":2,"accession":"OP555660","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0593/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555660/2022-09-14"},"date":{"value":"2022-09-14"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OQ451901","node_attrs":{"div":6,"accession":"OQ451901","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI716"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ451901/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-607T","C2315T","G21250A","G40586A","G146821A","G160267A","G194895A"],"OPG002":["G146E"],"OPG002_dup":["G146E"],"OPG037":["S395F"]},"labels":{"aa":"OPG002: G146E; OPG002_dup: G146E; OPG037: S395F"}}}]},{"name":"NODE_0000058","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C15480T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}},"children":[{"name":"OP555642","node_attrs":{"div":2,"accession":"OP555642","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0571/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555642/2022-09-05"},"date":{"value":"2022-09-05"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["A19385T"],"OPG034":["F207L"]},"labels":{"aa":"OPG034: F207L"}}},{"name":"OP555630","node_attrs":{"div":2,"accession":"OP555630","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0559/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555630/2022-08-30"},"date":{"value":"2022-08-30"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G102204A","A136543-","T136544-","C136545-","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-"],"OPG121":["E139K"],"OPG153":["D382-","D383-","D384-","D385-"]},"labels":{"aa":"OPG121: E139K; OPG153: D382-, D383-, D384-, D385-"}}}]},{"name":"NODE_0000059","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G98456A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG118":["G4E"]},"labels":{"aa":"OPG118: G4E"}},"children":[{"name":"OP881941","node_attrs":{"div":9,"accession":"OP881941","author":{"author":"Gigante,C.,Ingram,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Geeter,E.,Li,Y.","value":"Gigante,C.,Ingram,A.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Geeter,E.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_AL0001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP881941/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G17735A","C25644T","G74526A","T97911C","C103258T","G141521A","G157338A","G157752A"],"OPG123":["D605N"]},"labels":{"aa":"OPG123: D605N"}}},{"name":"OR030924","node_attrs":{"div":4,"accession":"OR030924","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_13"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR030924/2022-06-29"},"date":{"value":"2022-06-29"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T606-","G18442A","G26858A","A28532-","T76087-","T80849-","A89106-","T155424-","G170981A"],"OPG044":["M148-"]},"labels":{"aa":"OPG044: M148-"}}}]},{"name":"NODE_0000060","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C43487T","C71729T","C101983T"],"OPG063":["D68N"],"OPG121":["S65L"]},"labels":{"aa":"OPG063: D68N; OPG121: S65L"}},"children":[{"name":"OQ503837","node_attrs":{"div":3,"accession":"OQ503837","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00460/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ503837/2023-01-23"},"date":{"value":"2023-01-23"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OR209311","node_attrs":{"div":3,"accession":"OR209311","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_TX0053"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OR209311/2023-01-XX"},"date":{"value":"2023-01-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000061","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C111391T","C119654T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","C152191T","A173314-","T173315-","A173316-","T173317-","C176178T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-"],"OPG130":["C171Y"],"OPG137":["S18L"],"OPG205":["H175Y"]},"labels":{"aa":"OPG130: C171Y; OPG137: S18L; OPG205: H175Y"}},"children":[{"name":"OQ973327","node_attrs":{"div":4,"accession":"OQ973327","author":{"author":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L.","value":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"case1_skin"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ973327/2022-09-06"},"date":{"value":"2022-09-06"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G173595-","G173596-","T173597-","T173598-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","A180535-","A180536-","T180537-","A180538-","G180539-","C180540-","G180541-","T180542-","A180543-","T180544-","C180545-","T180546-","T180547-","A180548-"]}}},{"name":"OQ973326","node_attrs":{"div":4,"accession":"OQ973326","author":{"author":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L.","value":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"case1_air"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ973326/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G2615-","A2616-","T2617-","A2618-","G2619-","A2620-","C2621-","A2622-","A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","T2653-","T2654-","T2655-","A2656-","C2657-","A2658-","C2659-","T2660-","T2661-","A194549-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","A196613-","A196614-"],"OPG002":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-"],"OPG002_dup":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-"]},"labels":{"aa":"OPG002: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-; OPG002_dup: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-"}}}]},{"name":"NODE_0000062","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C28887T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG045":["E126K"]},"labels":{"aa":"OPG045: E126K"}},"children":[{"name":"OX336038","node_attrs":{"div":1,"accession":"OX336038","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX336038/2022-08-31"},"date":{"value":"2022-08-31"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{}}},{"name":"OX291694","node_attrs":{"div":5,"accession":"OX291694","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX291694/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{"nuc":["C15311T","C54262T","G81015T","G141131A"],"OPG104":["T2K"]},"labels":{"aa":"OPG104: T2K"}}}]},{"name":"NODE_0000063","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G67955A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G184141A","A196614-"],"OPG085":["P193S"],"OPG210":["G929D"]},"labels":{"aa":"OPG085: P193S; OPG210: G929D"}},"children":[{"name":"OX291780","node_attrs":{"div":2,"accession":"OX291780","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX291780/2022-07-25"},"date":{"value":"2022-07-25"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{"nuc":["A173316-","T173317-"]}}},{"name":"OX291676","node_attrs":{"div":3,"accession":"OX291676","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX291676/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{"nuc":["G14590A","T133102-"]}}}]},{"name":"NODE_0000064","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G57076A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG074":["S17L"]},"labels":{"aa":"OPG074: S17L"}},"children":[{"name":"OX291435","node_attrs":{"div":1,"accession":"OX291435","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX291435/2022-07-25"},"date":{"value":"2022-07-25"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{"nuc":["T164536-","T164537-","G164538-","A164539-","A164540-","A164541-","A164542-","T164543-","T164544-","A164545-","T164546-","G164547-","A164548-","T164549-","A164550-","C164551-","C164552-","A164553-","T164554-","C164555-","T164556-","A173314-","T173315-","A173316-","T173317-"],"OPG189":["L402-","K403-","I404-","M405-","I406-","P407-","S408-"]},"labels":{"aa":"OPG189: L402-, K403-, I404-, M405-, I406-, P407-, S408-"}}},{"name":"OX291424","node_attrs":{"div":1,"accession":"OX291424","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX291424/2022-07-25"},"date":{"value":"2022-07-25"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000065","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C118421T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG136":["M389I"]},"labels":{"aa":"OPG136: M389I"}},"children":[{"name":"OP120938","node_attrs":{"div":2,"accession":"OP120938","author":{"author":"Aja-Macaya,P.,Rumbo-Feal,S.,Poza,M.,Canizares,A.,Vallejo,J.A.,Bou,G.","value":"Aja-Macaya,P.,Rumbo-Feal,S.,Poza,M.,Canizares,A.,Vallejo,J.A.,Bou,G."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MP03CHUAC"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Biomedical research institute (INIBIC), Microbiology"},"strain_display":{"value":"Spain/OP120938/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["C142607T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG163":["H136Y"]},"labels":{"aa":"OPG163: H136Y"}}},{"name":"NODE_0000066","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G133806A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}},"children":[{"name":"OP536771","node_attrs":{"div":4,"accession":"OP536771","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000393"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536771/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-607T","G63147A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C160426T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"OR264382","node_attrs":{"div":2,"accession":"OR264382","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"26_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264382/2022-07-19"},"date":{"value":"2022-07-19"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000068","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C73609T","C113740T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG093":["S211L"],"OPG133":["D653N"]},"labels":{"aa":"OPG093: S211L; OPG133: D653N"}},"children":[{"name":"OP626126","node_attrs":{"div":2,"accession":"OP626126","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI488"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP626126/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"OP594188","node_attrs":{"div":3,"accession":"OP594188","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI424"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP594188/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G8068A"]}}},{"name":"OQ773481","node_attrs":{"div":2,"accession":"OQ773481","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI862"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ773481/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150564-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}}]},{"name":"NODE_0000069","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G21655A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG037":["S260L"]},"labels":{"aa":"OPG037: S260L"}},"children":[{"name":"OP837354","node_attrs":{"div":1,"accession":"OP837354","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI592"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP837354/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"OP764629","node_attrs":{"div":1,"accession":"OP764629","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI571"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP764629/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"OQ451900","node_attrs":{"div":1,"accession":"OQ451900","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI715"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ451900/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-607T"]}}}]},{"name":"NODE_0000070","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","G145790A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OQ348891","node_attrs":{"div":2,"accession":"OQ348891","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000144/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDPH, VRDL"},"strain_display":{"value":"USA/OQ348891/2022-06-25"},"date":{"value":"2022-06-25"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T6976-","C117143T"]}}},{"name":"NODE_0000071","node_attrs":{"div":5,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G1512A","G12099A","C143551T","G160358A","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","C195698T"],"OPG001":["Q22*"],"OPG001_dup":["Q22*"],"OPG023":["R268*"]},"labels":{"aa":"OPG001: Q22*; OPG001_dup: Q22*; OPG023: R268*"}},"children":[{"name":"OQ503818","node_attrs":{"div":8,"accession":"OQ503818","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00425/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ503818/2022-12-03"},"date":{"value":"2022-12-03"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G44107A","G107064A","T133177-","C133178-","T133179-","T133180-","T133181-","C133182-","T133183-","C133184-","A133185-","A133186-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C188361T"]}}},{"name":"OQ603483","node_attrs":{"div":5,"accession":"OQ603483","author":{"author":"Haw,M.,Kath,C.,Espinosa,A.,O'Neil,R.,Hacker,J.","value":"Haw,M.,Kath,C.,Espinosa,A.,O'Neil,R.,Hacker,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000214/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDPH, VRDL"},"strain_display":{"value":"USA/OQ603483/2023-01-31"},"date":{"value":"2023-01-31"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C942T","G196268A"],"OPG001":["E212K"],"OPG001_dup":["E212K"]},"labels":{"aa":"OPG001: E212K; OPG001_dup: E212K"}}}]}]},{"name":"NODE_0000072","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G2146A","C39044T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T187876C","C195064T"]}},"children":[{"name":"OQ503829","node_attrs":{"div":6,"accession":"OQ503829","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00406/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ503829/2023-01-09"},"date":{"value":"2023-01-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C2749T","G112552A","C167231T","G194461A"],"OPG002":["M1I"],"OPG002_dup":["M1I"],"OPG132":["S330L"]},"labels":{"aa":"OPG002: M1I; OPG002_dup: M1I; OPG132: S330L"}}},{"name":"NODE_0000073","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A24345G","T170904-"]}},"children":[{"name":"OQ644777","node_attrs":{"div":4,"accession":"OQ644777","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00471/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ644777/2023-02-13"},"date":{"value":"2023-02-13"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ644776","node_attrs":{"div":4,"accession":"OQ644776","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00470/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ644776/2023-02-13"},"date":{"value":"2023-02-13"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000074","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G162623A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG188":["R343K"]},"labels":{"aa":"OPG188: R343K"}},"children":[{"name":"OR087002","node_attrs":{"div":1,"accession":"OR087002","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_193/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR087002/2022-08-03"},"date":{"value":"2022-08-03"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-"]}}},{"name":"NODE_0000075","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C110147T"]}},"children":[{"name":"OR035731","node_attrs":{"div":3,"accession":"OR035731","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_125"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035731/2022-09-20"},"date":{"value":"2022-09-20"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G61361A"]}}},{"name":"OR035708","node_attrs":{"div":3,"accession":"OR035708","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_102"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035708/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C60081T","T196712-","A196713-","T196714-"]}}}]}]},{"name":"NODE_0000076","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","A41654-","A41655-","T41656-","A41657-","C41658-","T41659-","A41660-","A41661-","T41662-","T41663-","T41664-","G41665-","T41666-","T41667-","T41668-","T41669-","A41670-","C41671-","T41672-","C41673-","T41674-","A41675-","T41676-","A41677-","C118161T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG061":["V72-","K73-","Q74-","I75-","S76-","I77-"],"OPG136":["R476Q"]},"labels":{"aa":"OPG061: V72-, K73-, Q74-, I75-, S76-, I77-; OPG136: R476Q"}},"children":[{"name":"OR035716","node_attrs":{"div":6,"accession":"OR035716","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_110"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035716/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T607-","G36963A","-41654A","-41655A","-41656T","-41657A","-41658C","-41659T","-41660A","-41661A","-41662T","-41663T","-41664T","-41665G","-41666T","-41667T","-41668T","-41669T","-41670A","-41671C","-41672T","-41673C","-41674T","-41675A","-41676T","-41677A","G48024A","C109810T","G149818A","C170573T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","T196712-","A196713-","T196714-"],"OPG055":["R41C"],"OPG061":["-72V","-73K","-74Q","-75I","-76S","-77I"],"OPG129":["D399N"],"OPG176":["D4N"],"OPG198":["S179L"]},"labels":{"aa":"OPG055: R41C; OPG061: -72V, -73K, -74Q, -75I, -76S, -77I; OPG129: D399N; OPG176: D4N; OPG198: S179L"}}},{"name":"OR264421","node_attrs":{"div":1,"accession":"OR264421","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"46_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264421/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"OPG061":["R71-"]},"labels":{"aa":"OPG061: R71-"}}},{"name":"OR264423","node_attrs":{"div":1,"accession":"OR264423","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"46_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264423/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"OPG061":["S78-"]},"labels":{"aa":"OPG061: S78-"}}}]},{"name":"NODE_0000077","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133100-","T133101-","T133102-","C147965T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG172":["S180F"]},"labels":{"aa":"OPG172: S180F"}},"children":[{"name":"OR095046","node_attrs":{"div":1,"accession":"OR095046","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Van Holm,B.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Van Holm,B.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_228/Belgium/2022'"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR095046/2022-08-12"},"date":{"value":"2022-08-12"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C196881-","G196882-","T196883-"]}}},{"name":"NODE_0000078","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C28168T","T133097-","T133098-","T133099-","A173314-","T173315-","A173316-","T173317-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","C179470T","A196614-"],"OPG208":["P69S"]},"labels":{"aa":"OPG208: P69S"}},"children":[{"name":"OQ973328","node_attrs":{"div":3,"accession":"OQ973328","author":{"author":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L.","value":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"case6_air"},"clade_membership":{"value":"IIb"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ973328/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G2615-","A2616-","T2617-","A2618-","G2619-","A2620-","C2621-","A2622-","A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","T2653-","T2654-","T2655-","A2656-","C2657-","A2658-","C2659-","T2660-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","C194595-"],"OPG002":["C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-"],"OPG002_dup":["C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-"]},"labels":{"aa":"OPG002: C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-; OPG002_dup: C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-"}}},{"name":"OQ973329","node_attrs":{"div":3,"accession":"OQ973329","author":{"author":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L.","value":"Raymenants,J.,Van Gestel,L.,Coppens,J.,de Block,T.,Bangwen,E.,Rutgers,J.,Hens,M.,De Vos,E.,Coppens,S.,Keyaerts,E.,Andre,E.,Rezende,A.M.,Van Esbroeck,M.,Vercauteren,K.,Liesenborghs,L."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"case6_skin"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ973329/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C173474-","G173475-","A173476-","C173477-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-","A180535-","A180536-","T180537-","A180538-","G180539-","C180540-","G180541-","T180542-","A180543-","T180544-","C180545-","T180546-","T180547-","A180548-"]}}}]}]},{"name":"NODE_0000079","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C130606T"]}},"children":[{"name":"OR759155","node_attrs":{"div":1,"accession":"OR759155","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL065/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759155/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000080","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C45203T","C88917T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}},"children":[{"name":"OQ627927","node_attrs":{"div":3,"accession":"OQ627927","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"INMI-18982022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"strain_display":{"value":"Italy/OQ627927/2022-08-16"},"date":{"value":"2022-08-16"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{}}},{"name":"OQ570420","node_attrs":{"div":3,"accession":"OQ570420","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"INMI-14732022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"strain_display":{"value":"Italy/OQ570420/2022-08-11"},"date":{"value":"2022-08-11"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000081","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","C168943T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OR095049","node_attrs":{"div":1,"accession":"OR095049","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_231/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR095049/2022-08-12"},"date":{"value":"2022-08-12"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T196852-","G196853-","T196854-"]}}},{"name":"OR086979","node_attrs":{"div":2,"accession":"OR086979","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_170/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR086979/2022-07-27"},"date":{"value":"2022-07-27"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C33863T","-151508A","-151509A","-151510T","-151511G","-151512T","-151513C","-151514T","-151515C","-151516G","-151517T","-151518G","-151519G","-151520G","-151521G","-151522C","-151523A","-151524T","T196618-","A196619-"],"OPG052":["E45K"]},"labels":{"aa":"OPG052: E45K"}}},{"name":"OR086964","node_attrs":{"div":1,"accession":"OR086964","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_155/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR086964/2022-07-27"},"date":{"value":"2022-07-27"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000082","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G64522A","T133102-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"]}},"children":[{"name":"OR095045","node_attrs":{"div":1,"accession":"OR095045","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_227/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR095045/2022-08-12"},"date":{"value":"2022-08-12"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-606T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196614A"]}}},{"name":"OX297403","node_attrs":{"div":1,"accession":"OX297403","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX297403/2022-08-09"},"date":{"value":"2022-08-09"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{"nuc":["T133101-"]}}},{"name":"OX261749","node_attrs":{"div":1,"accession":"OX261749","lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX261749/2022-07-20"},"date":{"value":"2022-07-20"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{"nuc":["-133102T","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-"]}}}]},{"name":"NODE_0000083","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C13653T","C116100T","G150376A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG025":["D539N"],"OPG176":["D190N"]},"labels":{"aa":"OPG025: D539N; OPG176: D190N"}},"children":[{"name":"LC722946","node_attrs":{"div":3,"accession":"LC722946","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/TKY220091/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC722946/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000084","node_attrs":{"div":5,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G121971A","G187059A"]}},"children":[{"name":"OP588282","node_attrs":{"div":6,"accession":"OP588282","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI419"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP588282/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G44231A","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OP689687","node_attrs":{"div":5,"accession":"OP689687","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI534"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP689687/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"OQ773494","node_attrs":{"div":7,"accession":"OQ773494","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI875"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ773494/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G86751A","G86752A","G150551-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG108":["A103V"]},"labels":{"aa":"OPG108: A103V"}}}]}]},{"name":"NODE_0000085","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G169928A"],"OPG197":["D87N"]},"labels":{"aa":"OPG197: D87N"}},"children":[{"name":"NODE_0000086","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G10118A","C15004T"],"OPG021":["E178K"]},"labels":{"aa":"OPG021: E178K"}},"children":[{"name":"ON983165","node_attrs":{"div":5,"accession":"ON983165","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3686/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON983165/2022-06-14"},"date":{"value":"2022-06-14"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["G16819A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A163211-","A163212-","C163213-","T163214-","C180825T"],"OPG029":["S84L"],"OPG209":["S103F"]},"labels":{"aa":"OPG029: S84L; OPG209: S103F"}}},{"name":"ON751962","node_attrs":{"div":3,"accession":"ON751962","author":{"author":"Claro,I.M.,de Lima,E.L.,Romano,C.M.,Candido,D.S.,Lindoso,J.A.L.,Barra,L.A.C.,Borges,L.M.S.,Medeiros,L.A.,Tomishige,M.Y.S.,Ramundo,M.S.,Moutinho,T.,da Silva,A.J.D.,Rodrigues,C.C.M.,de Azevedo,L.C.F.,Villas-Boas,L.S.,da Silva,C.A.M.,Coletti,T.M.,O'Toole,A.,Quick,J.,Loman,N.,Rambaut,A.,Faria,N.R.,Figueiredo-Mello,C.,Sabino,E.C.","value":"Claro,I.M.,de Lima,E.L.,Romano,C.M.,Candido,D.S.,Lindoso,J.A.L.,Barra,L.A.C.,Borges,L.M.S.,Medeiros,L.A.,Tomishige,M.Y.S.,Ramundo,M.S.,Moutinho,T.,da Silva,A.J.D.,Rodrigues,C.C.M.,de Azevedo,L.C.F.,Villas-Boas,L.S.,da Silva,C.A.M.,Coletti,T.M.,O'Toole,A.,Quick,J.,Loman,N.,Rambaut,A.,Faria,N.R.,Figueiredo-Mello,C.,Sabino,E.C."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/BR0001/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Imperial College London, School of Public Health"},"strain_display":{"value":"Brazil/ON751962/2022-06-07"},"date":{"value":"2022-06-07"},"country":{"value":"Brazil"}},"branch_attrs":{"mutations":{"nuc":["T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","G173575-","A173576-","G173577-","A173578-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000087","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G58518A"]}},"children":[{"name":"OP626120","node_attrs":{"div":8,"accession":"OP626120","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI482"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP626120/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G3079A","C23345T","C23353T","C23356T","C151626T","C157938T","C194131T"],"OPG003":["S510L"],"OPG003_dup":["S510L"],"OPG039":["D255N","D256N"],"OPG178":["Q40*"]},"labels":{"aa":"OPG003: S510L; OPG003_dup: S510L; OPG039: D255N, D256N; OPG178: Q40*"}}},{"name":"OP594200","node_attrs":{"div":4,"accession":"OP594200","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI436"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP594200/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G59922A","G112249A"],"OPG131":["E104K"]},"labels":{"aa":"OPG131: E104K"}}}]}]},{"name":"NODE_0000088","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G70190A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG089":["E109K"]},"labels":{"aa":"OPG089: E109K"}},"children":[{"name":"ON954773","node_attrs":{"div":2,"accession":"ON954773","author":{"author":"Gigante,C.M.,Ventura,J.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y.","value":"Gigante,C.M.,Ventura,J.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_CA002"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"strain_display":{"value":"USA/ON954773/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G83568A"],"OPG105":["A815T"]},"labels":{"aa":"OPG105: A815T"}}},{"name":"OQ427119","node_attrs":{"div":2,"accession":"OQ427119","author":{"author":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Weigand,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y.","value":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Weigand,M.,Knipe,K.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_OH0004"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ427119/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G126310A","A173316-","T173317-"],"OPG148":["E109K"]},"labels":{"aa":"OPG148: E109K"}}},{"name":"OR035734","node_attrs":{"div":2,"accession":"OR035734","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_128"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035734/2022-10-10"},"date":{"value":"2022-10-10"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G164038A","T196712-","A196713-","T196714-"],"OPG189":["E236K"]},"labels":{"aa":"OPG189: E236K"}}},{"name":"OR035673","node_attrs":{"div":3,"accession":"OR035673","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_67"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035673/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G60855A","G71907A"]}}}]},{"name":"NODE_0000089","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C77462T"],"OPG098":["S188F"]},"labels":{"aa":"OPG098: S188F"}},"children":[{"name":"OP440592","node_attrs":{"div":1,"accession":"OP440592","author":{"author":"Hemarajata,P.,Green,N.M.","value":"Hemarajata,P.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00013/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP440592/2022-07-22"},"date":{"value":"2022-07-22"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A763-","A764-","T765-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196715-","T196716-","T196717-"]}}},{"name":"OP451007","node_attrs":{"div":1,"accession":"OP451007","author":{"author":"Gigante,C.M.,Pavlick,J.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y.","value":"Gigante,C.M.,Pavlick,J.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_GA0009"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP451007/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000090","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C111164T","A143676G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C152385T"],"OPG130":["E247K"],"OPG165":["N54S"]},"labels":{"aa":"OPG130: E247K; OPG165: N54S"}},"children":[{"name":"OR759186","node_attrs":{"div":4,"accession":"OR759186","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL098/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759186/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"OR759183","node_attrs":{"div":4,"accession":"OR759183","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL095/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759183/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000091","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G106113A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C189810T"]}},"children":[{"name":"OQ644781","node_attrs":{"div":8,"accession":"OQ644781","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00475/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ644781/2022-11-22"},"date":{"value":"2022-11-22"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G13224A","C22664T","C23353T","G24446A","G25294A","C25308T"],"OPG024":["S2L"],"OPG038":["D166N"],"OPG039":["D256N"],"OPG040":["S62L","P345S"]},"labels":{"aa":"OPG024: S2L; OPG038: D166N; OPG039: D256N; OPG040: S62L, P345S"}}},{"name":"NODE_0000092","node_attrs":{"div":5,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G66587A","G143857A","C144237T","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG165":["S241L"]},"labels":{"aa":"OPG165: S241L"}},"children":[{"name":"OQ918699","node_attrs":{"div":5,"accession":"OQ918699","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00488/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ918699/2023-02-20"},"date":{"value":"2023-02-20"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","-179176A","-179177T","-179178A"]}}},{"name":"OQ918700","node_attrs":{"div":5,"accession":"OQ918700","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00489/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ918700/2023-02-20"},"date":{"value":"2023-02-20"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OQ918698","node_attrs":{"div":5,"accession":"OQ918698","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00487/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ918698/2023-02-20"},"date":{"value":"2023-02-20"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179082C","-179083A","-179084T","-179085T","-179086A","-179087T","-179088A","-179089T","-179090A","-179091C","-179092A","-179093T","-179094T","-179095A","-179096T","-179097A","-179098T","-179099A","-179100C","-179101A","-179102T","-179103T","-179104A","-179105T","-179106A","-179107T","-179108A","-179109C","-179110A","-179111T","-179112T","-179113A","-179114T","-179115A","-179116T","-179117A","-179118C","-179119A","-179120T","-179121T","-179122A","-179123T","-179124A","-179125T","-179126A","-179127C","-179128A","-179129T","-179130T","-179131A","-179132T","-179133A","-179134T","-179135A","-179136C","-179137A","-179138T","-179139T","-179140A","-179141T","-179142A","-179143T","-179144A","-179145C","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-"]}}}]}]},{"name":"NODE_0000093","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C34784T","C101418T","G109844A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG054":["D405N"],"OPG120":["D111N"]},"labels":{"aa":"OPG054: D405N; OPG120: D111N"}},"children":[{"name":"OR743495","node_attrs":{"div":4,"accession":"OR743495","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1026"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR743495/2023-09-XX"},"date":{"value":"2023-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G145312A","-179194A","-179195T","C179265-","A179266-","T179267-"]}}},{"name":"OR743494","node_attrs":{"div":3,"accession":"OR743494","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1025"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR743494/2023-09-XX"},"date":{"value":"2023-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000094","node_attrs":{"div":6,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C45528T","C84767T","C170791T"],"OPG064":["R124K"]},"labels":{"aa":"OPG064: R124K"}},"children":[{"name":"OR743498","node_attrs":{"div":6,"accession":"OR743498","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1029"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR743498/2023-10-XX"},"date":{"value":"2023-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-179263G","-179264C"]}}},{"name":"OR743497","node_attrs":{"div":8,"accession":"OR743497","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1028"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR743497/2023-10-XX"},"date":{"value":"2023-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G143777A","G175934A","-179194A","-179195T","C179265-","A179266-","T179267-"],"OPG165":["V88I"]},"labels":{"aa":"OPG165: V88I"}}}]}]},{"name":"OR126131_NODE_0000067_merged","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C141757T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OR126131","node_attrs":{"div":5,"accession":"OR126131","author":{"author":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C.","value":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"HRYC_MPXV001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Hospital Ramon y Cajal, Microbiology"},"strain_display":{"value":"Spain/OR126131/2022-09-21"},"date":{"value":"2022-09-21"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["C11749-","C34432T","C48324T","G101294A","G190695A"],"OPG016":["E96K"],"OPG053":["E87K"],"OPG120":["S152L"]},"labels":{"aa":"OPG016: E96K; OPG053: E87K; OPG120: S152L"}}},{"name":"NODE_0000067","node_attrs":{"div":3,"lineage":{"value":"B.1.18"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C43706T","T124690C"]},"labels":{"clade":"B.1.18"}},"children":[{"name":"OP628451","node_attrs":{"div":3,"accession":"OP628451","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.18"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-083401/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP628451/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OQ148474","node_attrs":{"div":9,"accession":"OQ148474","author":{"author":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"lineage":{"value":"B.1.18"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LBMB-UTP_MP-025_VAC"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"strain_display":{"value":"Colombia/OQ148474/2022-11-15"},"date":{"value":"2022-11-15"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G67758A","C128242T","G144572A","C166940T","C168829T","C170049T"],"OPG150":["S155F"],"OPG166":["A59T"]},"labels":{"aa":"OPG150: S155F; OPG166: A59T"}}},{"name":"OQ557948","node_attrs":{"div":8,"accession":"OQ557948","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"lineage":{"value":"B.1.18"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_NY0009"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ557948/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G24063A","C25370T","G54088A","G108462A","C159779T","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG039":["S19F"],"OPG040":["E37K"],"OPG185":["S288L"]},"labels":{"aa":"OPG039: S19F; OPG040: E37K; OPG185: S288L"}}}]}]},{"name":"NODE_0000095","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C6310T","C81194T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G190900A"],"OPG016":["R164K"]},"labels":{"aa":"OPG016: R164K"}},"children":[{"name":"OQ503839","node_attrs":{"div":4,"accession":"OQ503839","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00463/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ503839/2023-01-26"},"date":{"value":"2023-01-26"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A39081T","C102294T","T179244-"],"OPG057":["I372N"],"OPG121":["Q169*"]},"labels":{"aa":"OPG057: I372N; OPG121: Q169*"}}},{"name":"NODE_0000096","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","A39482C","A170123-","T170124-","A170125-","A170126-","C179145-"],"OPG057":["H238Q"],"OPG198":["K30-"]},"labels":{"aa":"OPG057: H238Q; OPG198: K30-"}},"children":[{"name":"OP680504","node_attrs":{"div":3,"accession":"OP680504","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00226/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP680504/2022-10-03"},"date":{"value":"2022-10-03"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OQ503844","node_attrs":{"div":3,"accession":"OQ503844","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00468/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ503844/2023-01-26"},"date":{"value":"2023-01-26"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-","A181373-","T181374-","C181375-","T181376-","C181377-","T181378-","G181379-","G181380-","C181381-","T181382-","A181383-","T181384-","A181385-","T181386-","A181387-","T181388-","C181389-","T181390-","T181391-","A181392-","C181393-","G181394-","G181395-","T181396-","G181397-","A181398-","C181399-","A181400-","T181401-","G181402-","T181403-","T181404-","C181405-","G181406-","T181407-","G181408-","G181409-","T181410-","G181411-","T181412-","T181413-","A181414-","T181415-","G181416-","A181417-","A181418-","A181419-","C181420-","A181421-","T181422-","G181423-","T181424-","A181425-","T181426-","G181427-","A181428-","G181429-","A181430-","A181431-","A181432-","A181433-","A181434-","C181435-","T181436-","G181437-","C181438-","G181439-","T181440-","T181441-","G181442-","T181443-","A181444-","T181445-","C181446-","A181447-","T181448-","G181449-","A181450-","C181451-"]}}}]},{"name":"NODE_0000097","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G159399A","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"]}},"children":[{"name":"OP689657","node_attrs":{"div":3,"accession":"OP689657","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI504"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP689657/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OP689655","node_attrs":{"div":3,"accession":"OP689655","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI502"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP689655/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000098","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C118453T","G137276A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177009A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196614-"],"OPG136":["E379K"],"OPG153":["S131F"],"OPG205":["E452K"]},"labels":{"aa":"OPG136: E379K; OPG153: S131F; OPG205: E452K"}},"children":[{"name":"OQ331006","node_attrs":{"div":4,"accession":"OQ331006","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00397/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ331006/2023-01-03"},"date":{"value":"2023-01-03"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G635-","A636-","A637-","G39327A","T196627-","C196628-","T196629-"],"OPG057":["A290V"]},"labels":{"aa":"OPG057: A290V"}}},{"name":"NODE_0000099","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C117119T"]}},"children":[{"name":"OQ331007","node_attrs":{"div":4,"accession":"OQ331007","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00398/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ331007/2023-01-03"},"date":{"value":"2023-01-03"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499970","node_attrs":{"div":4,"accession":"OR499970","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00513/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499970/2023-05-04"},"date":{"value":"2023-05-04"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T605-"]}}},{"name":"OR499971","node_attrs":{"div":6,"accession":"OR499971","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00514/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499971/2023-05-04"},"date":{"value":"2023-05-04"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T39397C","T178873C","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG057":["N267D"]},"labels":{"aa":"OPG057: N267D"}}},{"name":"OR499968","node_attrs":{"div":5,"accession":"OR499968","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00511/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499968/2023-05-04"},"date":{"value":"2023-05-04"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T39076-","T39077-","T39078-","A39079-","A39080-","A39081-","T39082-","T39083-","T39084-","A176368T","A190409-","A190410-","T190411-","G190412-","G190413-","A190414-","T190415-","T190416-","C190417-","G190418-","C190419-","G190420-","T190421-","A190422-","T190423-","A190424-","G190425-","C190426-","T190427-","A190428-","T190429-","T190430-","T190431-","A190432-","C190433-","G190434-","T190435-","A190436-","T190437-","T190438-","A190439-","G190440-","T190441-","A190442-","T190443-","C190444-","G190445-","G190446-","C190447-","A190448-","T190449-","C190450-","T190451-","C190452-","T190453-","T190454-","T190455-","T190456-","G190457-","T190458-","A190459-","T190460-","C190461-","T190462-","T190463-","G190464-","T190465-","T190466-","A190467-","A190468-","T190469-","T190470-","G190471-","T190472-","C190473-","A190474-","C190475-","A190476-","A190477-","A190478-","C190479-","T190480-","A190481-","G190482-","T190483-","A190484-","C190485-","A190486-","T190487-","T190488-","A190489-","C190490-","T190491-","T190492-","C190493-","A190494-","A190495-","T190496-","C190497-","T190498-","G190499-","A190500-","A190501-","A190502-","A190503-","T190504-","A190505-"],"OPG205":["E238V"]},"labels":{"aa":"OPG205: E238V"}}}]}]},{"name":"NODE_0000100","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G50982A","T133102-","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"OR035670","node_attrs":{"div":3,"accession":"OR035670","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_64"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035670/2022-06-24"},"date":{"value":"2022-06-24"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C71644T","C127445T","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"],"OPG091":["S92L"],"OPG149":["P84S"]},"labels":{"aa":"OPG091: S92L; OPG149: P84S"}}},{"name":"OR035643","node_attrs":{"div":1,"accession":"OR035643","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_37"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035643/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-133102T"]}}},{"name":"OR030943","node_attrs":{"div":1,"accession":"OR030943","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_32"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR030943/2022-07-15"},"date":{"value":"2022-07-15"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133101-"]}}},{"name":"NODE_0000101","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G28334A","G47240A","C48569T"],"OPG044":["E82K"]},"labels":{"aa":"OPG044: E82K"}},"children":[{"name":"OR095057","node_attrs":{"div":4,"accession":"OR095057","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_239/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR095057/2022-08-12"},"date":{"value":"2022-08-12"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T196852-","G196853-","T196854-"]}}},{"name":"OR095054","node_attrs":{"div":4,"accession":"OR095054","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_236/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR095054/2022-08-12"},"date":{"value":"2022-08-12"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000102","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C156429T"]}},"children":[{"name":"NODE_0000103","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G162265A","C165278T"],"OPG188":["E224K"],"OPG190":["H53Y"]},"labels":{"aa":"OPG188: E224K; OPG190: H53Y"}},"children":[{"name":"OP019277","node_attrs":{"div":3,"accession":"OP019277","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1531254/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP019277/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP555487","node_attrs":{"div":4,"accession":"OP555487","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0391/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555487/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C139646T"],"OPG158":["E42K"]},"labels":{"aa":"OPG158: E42K"}}}]},{"name":"NODE_0000104","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C65571T","G144988A"]}},"children":[{"name":"OP013006","node_attrs":{"div":3,"accession":"OP013006","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3542/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP013006/2022-06-07"},"date":{"value":"2022-06-07"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"OP013017","node_attrs":{"div":3,"accession":"OP013017","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Chapel,M.,Tyler,A.,Haidl,E.,Domselaar,G.V.,Antonation,K.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Jolly,G.,Fafard,J.,Charest,H.,Levade,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3752/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP013017/2022-06-10"},"date":{"value":"2022-06-10"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"OP270027","node_attrs":{"div":4,"accession":"OP270027","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-4024/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP270027/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C181455T"],"OPG210":["Q34*"]},"labels":{"aa":"OPG210: Q34*"}}},{"name":"OP270025","node_attrs":{"div":6,"accession":"OP270025","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-4014/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP270025/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T","C45103T","G74933A","G131867A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG064":["E266K"],"OPG095":["R44Q"],"OPG151":["E982K"]},"labels":{"aa":"OPG064: E266K; OPG095: R44Q; OPG151: E982K"}}}]}]},{"name":"NODE_0000105","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C21128T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-196615A"],"OPG037":["E436K"]},"labels":{"aa":"OPG037: E436K"}},"children":[{"name":"OR264408","node_attrs":{"div":1,"accession":"OR264408","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"39_K"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264408/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}},{"name":"ON631963","node_attrs":{"div":1,"accession":"ON631963","author":{"author":"Hammerschlag,Y.,MacLeod,G.,Papadakis,G.,Adnan Sanchez,A.,Druce,J.,Savic,I.,Taiaroa,G.,Roberts,J.,Caly,L.,Williamson,D.A.,Cheng,A.C.,McMahon,J.H.","value":"Hammerschlag,Y.,MacLeod,G.,Papadakis,G.,Adnan Sanchez,A.,Druce,J.,Savic,I.,Taiaroa,G.,Roberts,J.,Caly,L.,Williamson,D.A.,Cheng,A.C.,McMahon,J.H."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPxV/VIDRL01/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"Victorian Infectious Diseases Reference Laboratory, Doherty Institute, Australia"},"strain_display":{"value":"Australia/ON631963/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["C133077T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264407","node_attrs":{"div":1,"accession":"OR264407","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"39_I"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264407/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000107","node_attrs":{"div":5,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T607-","A22452T","C66718T","C144356T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","C188683T","A196615-"],"OPG084":["S666L"]},"labels":{"aa":"OPG084: S666L"}},"children":[{"name":"OR264405","node_attrs":{"div":5,"accession":"OR264405","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"39_G"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264405/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}},{"name":"OR264404","node_attrs":{"div":5,"accession":"OR264404","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"39_D"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264404/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264406","node_attrs":{"div":5,"accession":"OR264406","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"39_H"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264406/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"]}}}]}]},{"name":"NODE_0000108","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C53342T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG071":["R366K"]},"labels":{"aa":"OPG071: R366K"}},"children":[{"name":"OQ451902","node_attrs":{"div":6,"accession":"OQ451902","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI717"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ451902/2022-11-XX"},"date":{"value":"2022-11-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-607T","C3602T","C124495T","G159789A","C170573T","G190695A","G193608A"],"OPG003":["E336K"],"OPG003_dup":["E336K"],"OPG016":["E96K"],"OPG198":["S179L"]},"labels":{"aa":"OPG003: E336K; OPG003_dup: E336K; OPG016: E96K; OPG198: S179L"}}},{"name":"NODE_0000109","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C156205T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}},"children":[{"name":"OP748969","node_attrs":{"div":2,"accession":"OP748969","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00283/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP748969/2022-10-19"},"date":{"value":"2022-10-19"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OP748964","node_attrs":{"div":2,"accession":"OP748964","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00278/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP748964/2022-10-20"},"date":{"value":"2022-10-20"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OQ427135","node_attrs":{"div":3,"accession":"OQ427135","author":{"author":"Gigante,C.,Steidley,B.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Davizon,E.,Li,Y.","value":"Gigante,C.,Steidley,B.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Davizon,E.,Li,Y."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_CO0004"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ427135/2022-11-XX"},"date":{"value":"2022-11-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G120238A","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","T136555-","A136556-","T136557-","G136558-","A136559-","T136560-","A136561-","T136562-","C136563-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG137":["E213K"],"OPG153":["I370-","I371-","D372-","D373-","D374-","D375-","D376-"]},"labels":{"aa":"OPG137: E213K; OPG153: I370-, I371-, D372-, D373-, D374-, D375-, D376-"}}},{"name":"NODE_0000110","node_attrs":{"div":3,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C109535T","A136516-","T136517-","A196657-","T196658-","A196659-"]}},"children":[{"name":"OQ331002","node_attrs":{"div":3,"accession":"OQ331002","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00374/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ331002/2022-11-23"},"date":{"value":"2022-11-23"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OQ331001","node_attrs":{"div":6,"accession":"OQ331001","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00373/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ331001/2022-11-23"},"date":{"value":"2022-11-23"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A763-","A764-","T765-","A11160G","T20384A","T130733C","-179145C","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","C196738-","C196739-","T196740-"],"OPG023":["F581L"],"OPG151":["C604R"]},"labels":{"aa":"OPG023: F581L; OPG151: C604R"}}}]}]}]},{"name":"NODE_0000111","node_attrs":{"div":1,"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G181367A","A196614-"]},"labels":{"clade":"B.1.9"}},"children":[{"name":"ON843175","node_attrs":{"div":1,"accession":"ON843175","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0043/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/ON843175/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000112","node_attrs":{"div":2,"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G176823A"],"OPG205":["E390K"]},"labels":{"aa":"OPG205: E390K"}},"children":[{"name":"ON880538","node_attrs":{"div":3,"accession":"ON880538","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3336/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880538/2022-06-01"},"date":{"value":"2022-06-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C32627T"]}}},{"name":"NODE_0000113","node_attrs":{"div":3,"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-606T","A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","C57110T","-196614A"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG074":["E6K"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG074: E6K"}},"children":[{"name":"ON649713","node_attrs":{"div":3,"accession":"ON649713","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.D.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Carvalho,I.L.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0020/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute National de Saude Doutor Ricardo Jorge (INSA), Portugal"},"strain_display":{"value":"Portugal/ON649713/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OP555532","node_attrs":{"div":4,"accession":"OP555532","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0451/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555532/2022-08-04"},"date":{"value":"2022-08-04"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159148A"],"OPG185":["D78N"]},"labels":{"aa":"OPG185: D78N"}}}]},{"name":"NODE_0000114","node_attrs":{"div":4,"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C34432T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G155157A"],"OPG053":["E87K"],"OPG181":["R249K"]},"labels":{"aa":"OPG053: E87K; OPG181: R249K"}},"children":[{"name":"OP555506","node_attrs":{"div":4,"accession":"OP555506","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0413/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555506/2022-07-26"},"date":{"value":"2022-07-26"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000115","node_attrs":{"div":5,"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C68792T"]}},"children":[{"name":"OP555608","node_attrs":{"div":5,"accession":"OP555608","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0537/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555608/2022-08-19"},"date":{"value":"2022-08-19"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OP555607","node_attrs":{"div":6,"accession":"OP555607","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.9"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0536/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555607/2022-08-22"},"date":{"value":"2022-08-22"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G13563A"],"OPG025":["P569S"]},"labels":{"aa":"OPG025: P569S"}}}]}]}]}]},{"name":"NODE_0000116","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G102694A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}},"children":[{"name":"OP863230","node_attrs":{"div":6,"accession":"OP863230","author":{"author":"Haw,M.,Probert,W.,Espinosa,A.,Kath,C.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Haw,M.,Probert,W.,Espinosa,A.,Kath,C.,O'Neil,R.,Bell,J.,Hacker,J."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/CA-CDPH-000056/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDPH, VRDL"},"strain_display":{"value":"USA/OP863230/2022-10-07"},"date":{"value":"2022-10-07"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A31053G","G34502A","G147352A","G151540A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","G189258A"],"OPG047":["C48R"],"OPG171":["R122K"],"OPG178":["G11E"]},"labels":{"aa":"OPG047: C48R; OPG171: R122K; OPG178: G11E"}}},{"name":"NODE_0000117","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G28490A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG044":["D134N"]},"labels":{"aa":"OPG044: D134N"}},"children":[{"name":"OP422342","node_attrs":{"div":3,"accession":"OP422342","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1539124/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP422342/2022-08-02"},"date":{"value":"2022-08-02"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{"nuc":["C110960T"]}}},{"name":"OP422341","node_attrs":{"div":2,"accession":"OP422341","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1538395/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP422341/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000118","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C179853T"]}},"children":[{"name":"OP555651","node_attrs":{"div":3,"accession":"OP555651","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0580/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555651/2022-09-09"},"date":{"value":"2022-09-09"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C121514T"],"OPG140":["G78E"]},"labels":{"aa":"OPG140: G78E"}}},{"name":"OP555639","node_attrs":{"div":3,"accession":"OP555639","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0568/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555639/2022-09-02"},"date":{"value":"2022-09-02"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G101192A"],"OPG120":["P186L"]},"labels":{"aa":"OPG120: P186L"}}}]},{"name":"NODE_0000119","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C12684T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG023":["E73K"]},"labels":{"aa":"OPG023: E73K"}},"children":[{"name":"OQ331004","node_attrs":{"div":2,"accession":"OQ331004","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00393/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ331004/2022-12-13"},"date":{"value":"2022-12-13"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OQ644787","node_attrs":{"div":3,"accession":"OQ644787","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00481/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ644787/2023-01-18"},"date":{"value":"2023-01-18"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G90825A"]}}}]}]},{"name":"NODE_0000120","node_attrs":{"div":2,"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","G36617A","C159779T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG055":["S156L"],"OPG185":["S288L"]},"labels":{"aa":"OPG055: S156L; OPG185: S288L","clade":"B.1.14"}},"children":[{"name":"ON959133","node_attrs":{"div":2,"accession":"ON959133","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_NY002"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"strain_display":{"value":"USA/ON959133/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"ON959135","node_attrs":{"div":4,"accession":"ON959135","author":{"author":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Seabolt,M.H.,Zhao,H.,Wilkins,K.,Respress,J.,Howard,D.,Batra,D.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_NY004"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology"},"strain_display":{"value":"USA/ON959135/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G2132A","G96835A","C195078T"],"OPG002":["S207L"],"OPG002_dup":["S207L"],"OPG117":["D263N"]},"labels":{"aa":"OPG002: S207L; OPG002_dup: S207L; OPG117: D263N"}}},{"name":"ON694342","node_attrs":{"div":2,"accession":"ON694342","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI011"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON694342/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-606T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-","-196614A"]}}},{"name":"OR086956","node_attrs":{"div":5,"accession":"OR086956","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_147/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR086956/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-606T","C22880T","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","G158617A","C170573T"],"OPG038":["E94K"],"OPG198":["S179L"]},"labels":{"aa":"OPG038: E94K; OPG198: S179L"}}},{"name":"OX009124","node_attrs":{"div":4,"accession":"OX009124","author":{"author":"Pettke,A.,Filen,F.,Asgeirsson,H.,Glans,H.,Widgren,K.,Muradrasoli,S.,Helgesson,S.,Karlberg,M.L.,Walai,N.,Bjerkner,A.,Gourle,H.,Lindsjo,O.K.,Sonden,K.","value":"Pettke,A.,Filen,F.,Asgeirsson,H.,Glans,H.,Widgren,K.,Muradrasoli,S.,Helgesson,S.,Karlberg,M.L.,Walai,N.,Bjerkner,A.,Gourle,H.,Lindsjo,O.K.,Sonden,K."},"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Lesion"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Public Health Agency of Sweden, Unit for Laboratory Development and Technology Transfer , Folkhalsomyndigheten, 171 82 Solna"},"strain_display":{"value":"Sweden/OX009124/2022-05-22"},"date":{"value":"2022-05-22"},"country":{"value":"Sweden"}},"branch_attrs":{"mutations":{"nuc":["T602-","T603-","T604-","T605-","A8055-","A28529-","A28530-","T47054-","T76087-","T88836-","A91705-","A92907-","T103367-","T104687-","T148344A","A148345T","A151680-","A162904-","T163342-","T163597-","A170728-"],"OPG044":["K147-"],"OPG113":["I393-"],"OPG178":["T58-"],"OPG188":["K437-"],"OPG189":["F4-"],"OPG198":["K231-"]},"labels":{"aa":"OPG044: K147-; OPG113: I393-; OPG178: T58-; OPG188: K437-; OPG189: F4-; OPG198: K231-"}}},{"name":"NODE_0000121","node_attrs":{"div":3,"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G171270A","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","-196614A"],"OPG199":["D95N"]},"labels":{"aa":"OPG199: D95N"}},"children":[{"name":"OP382493","node_attrs":{"div":6,"accession":"OP382493","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00016"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382493/2022-07-22"},"date":{"value":"2022-07-22"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["G25999A","G97417A","G100939A"],"OPG042":["Q367*"],"OPG117":["E457K"]},"labels":{"aa":"OPG042: Q367*; OPG117: E457K"}}},{"name":"OP382492","node_attrs":{"div":4,"accession":"OP382492","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00015"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382492/2022-07-22"},"date":{"value":"2022-07-22"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["G161913A","A196856-","A196857-","A196858-"]}}},{"name":"OP555644","node_attrs":{"div":5,"accession":"OP555644","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.14"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0573/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555644/2022-09-06"},"date":{"value":"2022-09-06"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T594A","-606T","-607T","-608T","-609T","C93713T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G158549A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A","-196616T"]}}}]}]},{"name":"NODE_0000122","node_attrs":{"div":4,"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C9389T","C30154T","G161797A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A179266-","T179267-","A179270-","T179271-","A179272-","T179273-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","A179282-","A185557C"],"OPG188":["E68K"],"OPG210":["K1401T"]},"labels":{"aa":"OPG188: E68K; OPG210: K1401T","clade":"B.1.16"}},"children":[{"name":"OP459211","node_attrs":{"div":5,"accession":"OP459211","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-23596-O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"strain_display":{"value":"Colombia/OP459211/2022-08-29"},"date":{"value":"2022-08-29"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G170076A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP819959","node_attrs":{"div":6,"accession":"OP819959","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"SAN_INS_MPX_0971_L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP819959/2022-10-11"},"date":{"value":"2022-10-11"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G23673A","G37974A","-179266A","-179267T","-179270A","-179271T","-179272A","-179273T","-179275T","-179276T","-179277T","-179278A","-179279A","-179280A","-179282A"],"OPG039":["S149L"],"OPG056":["S354L"]},"labels":{"aa":"OPG039: S149L; OPG056: S354L"}}},{"name":"OP693647","node_attrs":{"div":4,"accession":"OP693647","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"DC_INS_MPX_0082_L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP693647/2022-08-08"},"date":{"value":"2022-08-08"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A1701-","C1702-","T1703-","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-","T196852-","G196853-","T196854-"]}}},{"name":"OQ197861","node_attrs":{"div":7,"accession":"OQ197861","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Rosales,A.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Rosales,A.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"DC_INS_MPX-1118-H"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OQ197861/2022-10-20"},"date":{"value":"2022-10-20"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G23118A","G74167A","T110647C","C179265-","G179268-","G179269-","C179274-","G179281-"],"OPG094":["D130N"],"OPG129":["T120A"]},"labels":{"aa":"OPG094: D130N; OPG129: T120A"}}},{"name":"NODE_0000123","node_attrs":{"div":5,"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G148403A"]}},"children":[{"name":"OP819955","node_attrs":{"div":13,"accession":"OP819955","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"VAC_INS_MPX_0962_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP819955/2022-10-13"},"date":{"value":"2022-10-13"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C53865T","C57810T","G69840A","C117200T","C124379T","G161421A","C178546T","-179266A","-179267T","-179270A","-179271T","-179272A","-179273T","-179275T","-179276T","-179277T","-179278A","-179279A","-179280A","-179282A","C188775T"],"OPG071":["D192N"],"OPG145":["H145Y"],"OPG187":["R267K"]},"labels":{"aa":"OPG071: D192N; OPG145: H145Y; OPG187: R267K"}}},{"name":"OP819954","node_attrs":{"div":7,"accession":"OP819954","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"VAC_INS_MPX_0960_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP819954/2022-10-15"},"date":{"value":"2022-10-15"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G89896A","G164843A","-179266A","-179267T","-179270A","-179271T","-179272A","-179273T","-179275T","-179276T","-179277T","-179278A","-179279A","-179280A","-179282A"],"OPG110":["E89K"],"OPG189":["G504E"]},"labels":{"aa":"OPG110: E89K; OPG189: G504E"}}},{"name":"OQ148473","node_attrs":{"div":6,"accession":"OQ148473","author":{"author":"Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LBMB-UTP_MP-021_VAC"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"strain_display":{"value":"Colombia/OQ148473/2022-11-11"},"date":{"value":"2022-11-11"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C133212-","C133213-","T133214-","C133215-","G133216-","A133217-","G133218-","T133219-","C133220-","T133221-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","C179265-","G179268-","G179269-","C179274-","G179281-","C188896T"]}}},{"name":"OQ696095","node_attrs":{"div":7,"accession":"OQ696095","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.16"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-30094O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ696095/2022-11-08"},"date":{"value":"2022-11-08"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","G104597A","C116175T","G150568A","C179265-","G179268-","G179269-","C179274-","G179281-"]}}}]}]},{"name":"NODE_0000124","node_attrs":{"div":2,"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A11326-","T11327-","C11328-","T11329-","A11330-","C11331-","G11332-","A11333-","T11334-","A11335-","T11336-","T11337-","A11338-","G11339-","A11340-","T11341-","A11342-","C11343-","T11344-","T11345-","C11346-","A11347-","C11348-","T11349-","C11350-","A11351-","A11352-","T11353-","G11354-","A11355-","A11356-","T11357-","C11358-","A11359-","A11360-","T11361-","C11362-","A11363-","C11364-","A11365-","C11366-","A11367-","A11368-","T11369-","C11370-","T11371-","A11372-","A11373-","T11374-","G11375-","T11376-","A11377-","G11378-","G11379-","T11380-","T11381-","T11382-","A11383-","T11384-","G11385-","A11386-","C11387-","A11388-","T11389-","A11390-","A11391-","T11392-","A11393-","G11394-","C11395-","A11396-","T11397-","T11398-","T11399-","T11400-","C11401-","A11402-","G11403-","C11404-","A11405-","G11406-","T11407-","T11408-","C11409-","A11410-","A11411-","T11412-","G11413-","T11414-","T11415-","T11416-","C11417-","T11418-","A11419-","G11420-","A11421-","T11422-","T11423-","C11424-","G11425-","T11426-","T11427-","G11428-","A11429-","T11430-","G11431-","G11432-","C11433-","A11434-","A11435-","T11436-","G11437-","G11438-","T11439-","T11440-","A11441-","T11442-","A11443-","C11444-","A11445-","T11446-","G11447-","T11448-","A11449-","T11450-","A11451-","T11452-","C11453-","C11454-","G11455-","T11456-","T11457-","A11458-","T11459-","T11460-","T11461-","G11462-","A11463-","T11464-","C11465-","T11466-","A11467-","A11468-","T11469-","G11470-","T11471-","T11472-","G11473-","A11474-","C11475-","A11476-","T11477-","C11478-","T11479-","G11480-","A11481-","A11482-","C11483-","C11484-","G11485-","G11486-","A11487-","T11488-","T11489-","C11490-","T11491-","A11492-","G11493-","C11494-","A11495-","G11496-","T11497-","A11498-","A11499-","A11500-","G11501-","A11502-","T11503-","A11504-","C11505-","T11506-","A11507-","G11508-","A11509-","G11510-","A11511-","T11512-","T11513-","G11514-","T11515-","T11516-","T11517-","A11518-","T11519-","T11520-","A11521-","T11522-","A11523-","T11524-","C11525-","T11526-","A11527-","A11528-","C11529-","A11530-","G11531-","C11532-","C11533-","T11534-","T11535-","G11536-","T11537-","G11538-","A11539-","A11540-","G11541-","A11542-","A11543-","G11544-","T11545-","G11546-","T11547-","T11548-","T11549-","C11550-","T11551-","C11552-","C11553-","T11554-","C11555-","G11556-","T11557-","T11558-","T11559-","G11560-","T11561-","C11562-","A11563-","A11564-","T11565-","C11566-","A11567-","T11568-","G11569-","T11570-","T11571-","A11572-","A11573-","T11574-","G11575-","T11576-","C11577-","T11578-","T11579-","T11580-","A11581-","A11582-","G11583-","A11584-","T11585-","A11586-","A11587-","G11588-","G11589-","T11590-","A11591-","G11592-","A11593-","C11594-","A11595-","A11596-","A11597-","T11598-","G11599-","T11600-","T11601-","T11602-","A11603-","T11604-","A11605-","G11606-","T11607-","A11608-","C11609-","T11610-","A11611-","A11612-","G11613-","A11614-","A11615-","T11616-","T11617-","G11618-","G11619-","G11620-","C11621-","A11622-","A11623-","A11624-","C11625-","A11626-","T11627-","A11628-","A11629-","G11630-","A11631-","C11632-","A11633-","T11634-","G11635-","T11636-","C11637-","A11638-","C11639-","A11640-","A11641-","A11642-","G11643-","A11644-","C11645-","C11646-","C11647-","T11648-","T11649-","T11650-","T11651-","T11652-","G11653-","T11654-","A11655-","T11656-","G11657-","T11658-","A11659-","T11660-","A11661-","A11662-","G11663-","T11664-","G11665-","T11666-","A11667-","G11668-","A11669-","A11670-","A11671-","T11672-","T11673-","A11674-","T11675-","A11676-","A11677-","C11678-","A11679-","T11680-","C11681-","C11682-","A11683-","T11684-","A11685-","G11686-","T11687-","T11688-","G11689-","G11690-","A11691-","T11692-","T11693-","C11694-","A11695-","C11696-","A11697-","T11698-","A11699-","G11700-","G11701-","T11702-","G11703-","T11704-","C11705-","C11706-","A11707-","A11708-","T11709-","C11710-","G11711-","G11712-","G11713-","A11714-","T11715-","C11716-","T11717-","C11718-","T11719-","C11720-","C11721-","A11722-","T11723-","C11724-","A11725-","T11726-","C11727-","G11728-","A11729-","G11730-","A11731-","T11732-","G11733-","A11734-","T11735-","T11736-","G11737-","A11738-","C11739-","G11740-","G11741-","C11742-","A11743-","T11744-","C11745-","T11746-","C11747-","C11748-","C11749-","C11750-","C11751-","T11752-","T11753-","C11754-","C11755-","T11756-","T11757-","T11758-","T11759-","T11760-","T11761-","A11762-","G11763-","T11764-","A11765-","G11766-","A11767-","T11768-","A11769-","T11770-","T11771-","T11772-","C11773-","A11774-","T11775-","C11776-","G11777-","T11778-","G11779-","T11780-","A11781-","A11782-","G11783-","A11784-","A11785-","T11786-","C11787-","A11788-","A11789-","T11790-","A11791-","T11792-","T11793-","A11794-","A11795-","T11796-","A11797-","T11798-","T11799-","T11800-","C11801-","T11802-","A11803-","A11804-","A11805-","G11806-","T11807-","A11808-","T11809-","C11810-","T11811-","G11812-","T11813-","G11814-","T11815-","A11816-","T11817-","A11818-","G11819-","C11820-","C11821-","T11822-","C11823-","T11824-","T11825-","T11826-","A11827-","T11828-","T11829-","T11830-","A11831-","C11832-","C11833-","A11834-","C11835-","A11836-","G11837-","C11838-","T11839-","C11840-","C11841-","A11842-","T11843-","A11844-","T11845-","T11846-","C11847-","C11848-","A11849-","A11850-","C11851-","A11852-","T11853-","G11854-","C11855-","A11856-","T11857-","T11858-","C11859-","C11860-","A11861-","C11862-","T11863-","A11864-","G11865-","A11866-","G11867-","G11868-","G11869-","A11870-","T11871-","A11872-","T11873-","C11874-","G11875-","A11876-","T11877-","A11878-","T11879-","C11880-","G11881-","C11882-","C11883-","G11884-","A11885-","A11886-","T11887-","G11888-","T11889-","C11890-","A11891-","T11892-","A11893-","T11894-","A11895-","C11896-","T11897-","C11898-","A11899-","A11900-","T11901-","T11902-","A11903-","G11904-","T11905-","A11906-","T11907-","A11908-","T11909-","G11910-","T11911-","T11912-","G11913-","G11914-","A11915-","G11916-","G11917-","A11918-","C11919-","A11920-","T11921-","C11922-","C11923-","G11924-","A11925-","G11926-","T11927-","T11928-","C11929-","A11930-","T11931-","T11932-","G11933-","T11934-","T11935-","T11936-","T11937-","C11938-","A11939-","A11940-","T11941-","A11942-","T11943-","C11944-","A11945-","A11946-","A11947-","G11948-","A11949-","G11950-","A11951-","T11952-","G11953-","G11954-","T11955-","T11956-","T11957-","C11958-","C11959-","T11960-","T11961-","A11962-","T11963-","C11964-","A11965-","T11966-","T11967-","T11968-","C11969-","T11970-","C11971-","C11972-","A11973-","T11974-","A11975-","G11976-","T11977-","G11978-","G11979-","T11980-","A11981-","C11982-","A11983-","A11984-","T11985-","A11986-","C11987-","T11988-","A11989-","C11990-","A11991-","C11992-","A11993-","T11994-","T11995-","A11996-","T11997-","T11998-","C11999-","C12000-","G12001-","T12002-","A12003-","C12004-","G12005-","G12006-","C12007-","T12008-","T12009-","T12010-","C12011-","C12012-","A12013-","T12014-","T12015-","C12016-","T12017-","C12018-","C12019-","A12020-","A12021-","A12022-","A12023-","A12024-","C12025-","A12026-","A12027-","T12028-","T12029-","T12030-","T12031-","A12032-","C12033-","C12034-","A12035-","A12036-","A12037-","T12038-","C12039-","T12040-","A12041-","A12042-","A12043-","T12044-","C12045-","T12046-","A12047-","C12048-","A12049-","T12050-","C12051-","T12052-","T12053-","T12054-","A12055-","T12056-","T12057-","G12058-","T12059-","A12060-","T12061-","C12062-","T12063-","A12064-","T12065-","A12066-","A12067-","T12068-","C12069-","A12070-","C12071-","T12072-","A12073-","T12074-","T12075-","T12076-","A12077-","G12078-","A12079-","T12080-","A12081-","A12082-","T12083-","C12084-","A12085-","G12086-","C12087-","C12088-","A12089-","T12090-","A12091-","A12092-","T12093-","T12094-","C12095-","C12096-","T12097-","C12098-","G12099-","A12100-","G12101-","T12102-","G12103-","C12104-","A12105-","A12106-","C12107-","A12108-","T12109-","G12110-","T12111-","T12112-","A12113-","G12114-","A12115-","T12116-","C12117-","G12118-","T12119-","C12120-","T12121-","A12122-","T12123-","A12124-","T12125-","A12126-","T12127-","G12128-","A12129-","A12130-","T12131-","A12132-","A12133-","G12134-","C12135-","C12136-","G12137-","T12138-","G12139-","T12140-","T12141-","A12142-","T12143-","C12144-","T12145-","A12146-","T12147-","T12148-","C12149-","C12150-","T12151-","T12152-","T12153-","C12154-","A12155-","T12156-","T12157-","A12158-","A12159-","C12160-","A12161-","A12162-","T12163-","T12164-","T12165-","A12166-","A12167-","C12168-","G12169-","A12170-","T12171-","G12172-","T12173-","C12174-","T12175-","A12176-","T12177-","A12178-","T12179-","C12180-","T12181-","A12182-","T12183-","A12184-","T12185-","G12186-","A12187-","G12188-","A12189-","T12190-","G12191-","A12192-","C12193-","T12194-","T12195-","A12196-","A12197-","T12198-","A12199-","T12200-","A12201-","A12202-","T12203-","A12204-","T12205-","T12206-","G12207-","A12208-","A12209-","G12210-","A12211-","G12212-","C12213-","T12214-","G12215-","T12216-","A12217-","C12218-","A12219-","A12220-","T12221-","A12222-","G12223-","T12224-","T12225-","T12226-","T12227-","T12228-","A12229-","T12230-","C12231-","T12232-","A12233-","T12234-","A12235-","G12236-","A12237-","A12238-","G149818A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G151362A"],"OPG023":["S222-","I223-","D224-","K225-","N226-","Y227-","C228-","T229-","A230-","L231-","Q232-","Y233-","Y234-","I235-","K236-","S237-","S238-","H239-","I240-","D241-","I242-","D243-","I244-","V245-","K246-","L247-","L248-","M249-","K250-","G251-","I252-","D253-","N254-","T255-","A256-","Y257-","S258-","Y259-","I260-","D261-","D262-","L263-","T264-","C265-","C266-","T267-","R268-","G269-","I270-","M271-","A272-","D273-","Y274-","L275-","N276-","S277-","D278-","Y279-","R280-","Y281-","N282-","K283-","D284-","V285-","D286-","L287-","D288-","L289-","V290-","K291-","L292-","F293-","L294-","E295-","N296-","G297-","K298-","P299-","Y300-","G301-","I302-","M303-","C304-","S305-","I306-","V307-","P308-","L309-","W310-","R311-","N312-","D313-","K314-","E315-","T316-","I317-","S318-","L319-","I320-","L321-","K322-","T323-","M324-","N325-","S326-","D327-","V328-","L329-","Q330-","H331-","I332-","L333-","I334-","E335-","Y336-","M337-","T338-","F339-","G340-","D341-","I342-","D343-","I344-","P345-","L346-","V347-","E348-","C349-","M350-","L351-","E352-","Y353-","G354-","A355-","V356-","V357-","N358-","K359-","E360-","A361-","I362-","H363-","R364-","Y365-","F366-","R367-","N368-","I369-","N370-","I371-","D372-","S373-","Y374-","T375-","M376-","K377-","Y378-","L379-","L380-","K381-","K382-","E383-","G384-","G385-","D386-","A387-","V388-","N389-","H390-","L391-","D392-","D393-","G394-","E395-","I396-","P397-","I398-","G399-","H400-","L401-","C402-","E403-","S404-","N405-","Y406-","G407-","C408-","Y409-","N410-","F411-","Y412-","T413-","Y414-","T415-","Y416-","K417-","K418-","G419-","L420-","C421-","D422-","M423-","S424-","Y425-","V426-","C427-","P428-","I429-","L430-","S431-","T432-","I433-","N434-","I435-","C436-","L437-","P438-","Y439-","L440-","K441-","D442-","I443-","N444-","M445-","I446-","D447-","K448-","R449-","G450-","E451-","T452-","L453-","L454-","H455-","K456-","A457-","V458-","R459-","Y460-","N461-","K462-","Q463-","S464-","L465-","V466-","S467-","L468-","L469-","L470-","E471-","S472-","G473-","S474-","D475-","V476-","N477-","I478-","R479-","S480-","N481-","N482-","G483-","Y484-","T485-","C486-","I487-","T488-","I489-","A490-","I491-","N492-","E493-","S494-","R495-","N496-","I497-","E498-","L499-","L500-","K501-","M502-","L503-","L504-","C505-","H506-","K507-","P508-","T509-","L510-","D511-","C512-","V513-","I514-","D515-","S516-","L517-","S518-","E519-","V520-","S521-","N522-","I523-","V524-","D525-"],"OPG176":["D4N"]},"labels":{"aa":"OPG023: S222-, I223-, D224-, K225-, N226-, Y227-, C228-, T229-, A230-, L231-, Q232-, Y233-, Y234-, I235-, K236-, S237-, S238-, H239-, I240-, D241-, I242-, D243-, I244-, V245-, K246-, L247-, L248-, M249-, K250-, G251-, I252-, D253-, N254-, T255-, A256-, Y257-, S258-, Y259-, I260-, D261-, D262-, L263-, T264-, C265-, C266-, T267-, R268-, G269-, I270-, M271-, A272-, D273-, Y274-, L275-, N276-, S277-, D278-, Y279-, R280-, Y281-, N282-, K283-, D284-, V285-, D286-, L287-, D288-, L289-, V290-, K291-, L292-, F293-, L294-, E295-, N296-, G297-, K298-, P299-, Y300-, G301-, I302-, M303-, C304-, S305-, I306-, V307-, P308-, L309-, W310-, R311-, N312-, D313-, K314-, E315-, T316-, I317-, S318-, L319-, I320-, L321-, K322-, T323-, M324-, N325-, S326-, D327-, V328-, L329-, Q330-, H331-, I332-, L333-, I334-, E335-, Y336-, M337-, T338-, F339-, G340-, D341-, I342-, D343-, I344-, P345-, L346-, V347-, E348-, C349-, M350-, L351-, E352-, Y353-, G354-, A355-, V356-, V357-, N358-, K359-, E360-, A361-, I362-, H363-, R364-, Y365-, F366-, R367-, N368-, I369-, N370-, I371-, D372-, S373-, Y374-, T375-, M376-, K377-, Y378-, L379-, L380-, K381-, K382-, E383-, G384-, G385-, D386-, A387-, V388-, N389-, H390-, L391-, D392-, D393-, G394-, E395-, I396-, P397-, I398-, G399-, H400-, L401-, C402-, E403-, S404-, N405-, Y406-, G407-, C408-, Y409-, N410-, F411-, Y412-, T413-, Y414-, T415-, Y416-, K417-, K418-, G419-, L420-, C421-, D422-, M423-, S424-, Y425-, V426-, C427-, P428-, I429-, L430-, S431-, T432-, I433-, N434-, I435-, C436-, L437-, P438-, Y439-, L440-, K441-, D442-, I443-, N444-, M445-, I446-, D447-, K448-, R449-, G450-, E451-, T452-, L453-, L454-, H455-, K456-, A457-, V458-, R459-, Y460-, N461-, K462-, Q463-, S464-, L465-, V466-, S467-, L468-, L469-, L470-, E471-, S472-, G473-, S474-, D475-, V476-, N477-, I478-, R479-, S480-, N481-, N482-, G483-, Y484-, T485-, C486-, I487-, T488-, I489-, A490-, I491-, N492-, E493-, S494-, R495-, N496-, I497-, E498-, L499-, L500-, K501-, M502-, L503-, L504-, C505-, H506-, K507-, P508-, T509-, L510-, D511-, C512-, V513-, I514-, D515-, S516-, L517-, S518-, E519-, V520-, S521-, N522-, I523-, V524-, D525-; OPG176: D4N","clade":"B.1.15"}},"children":[{"name":"ON694335","node_attrs":{"div":2,"accession":"ON694335","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI018"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON694335/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-","A196614-"]}}},{"name":"OP484673","node_attrs":{"div":5,"accession":"OP484673","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI352"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP484673/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C21128T","G74187T","C151111T"],"OPG037":["E436K"],"OPG094":["Q136H"]},"labels":{"aa":"OPG037: E436K; OPG094: Q136H"}}},{"name":"NODE_0000125","node_attrs":{"div":7,"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C8385T","-11326A","-11327T","-11328C","-11329T","-11330A","-11331C","-11332G","-11333A","-11334T","-11335A","-11336T","-11337T","-11338A","-11339G","-11340A","-11341T","-11342A","-11343C","-11344T","-11345T","-11346C","-11347A","-11348C","-11349T","-11350C","-11351A","-11352A","-11353T","-11354G","-11355A","-11356A","-11357T","-11358C","-11359A","-11360A","-11361T","-11362C","-11363A","-11364C","-11365A","-11366C","-11367A","-11368A","-11369T","-11370C","-11371T","-11372A","-11373A","-11374T","-11375G","-11376T","-11377A","-11378G","-11379G","-11380T","-11381T","-11382T","-11383A","-11384T","-11385G","-11386A","-11387C","-11388A","-11389T","-11390A","-11391A","-11392T","-11393A","-11394G","-11395C","-11396A","-11397T","-11398T","-11399T","-11400T","-11401C","-11402A","-11403G","-11404C","-11405A","-11406G","-11407T","-11408T","-11409C","-11410A","-11411A","-11412T","-11413G","-11414T","-11415T","-11416T","-11417C","-11418T","-11419A","-11420G","-11421A","-11422T","-11423T","-11424C","-11425G","-11426T","-11427T","-11428G","-11429A","-11430T","-11431G","-11432G","-11433C","-11434A","-11435A","-11436T","-11437G","-11438G","-11439T","-11440T","-11441A","-11442T","-11443A","-11444C","-11445A","-11446T","-11447G","-11448T","-11449A","-11450T","-11451A","-11452T","-11453C","-11454C","-11455G","-11456T","-11457T","-11458A","-11459T","-11460T","-11461T","-11462G","-11463A","-11464T","-11465C","-11466T","-11467A","-11468A","-11469T","-11470G","-11471T","-11472T","-11473G","-11474A","-11475C","-11476A","-11477T","-11478C","-11479T","-11480G","-11481A","-11482A","-11483C","-11484C","-11485G","-11486G","-11487A","-11488T","-11489T","-11490C","-11491T","-11492A","-11493G","-11494C","-11495A","-11496G","-11497T","-11498A","-11499A","-11500A","-11501G","-11502A","-11503T","-11504A","-11505C","-11506T","-11507A","-11508G","-11509A","-11510G","-11511A","-11512T","-11513T","-11514G","-11515T","-11516T","-11517T","-11518A","-11519T","-11520T","-11521A","-11522T","-11523A","-11524T","-11525C","-11526T","-11527A","-11528A","-11529C","-11530A","-11531G","-11532C","-11533C","-11534T","-11535T","-11536G","-11537T","-11538G","-11539A","-11540A","-11541G","-11542A","-11543A","-11544G","-11545T","-11546G","-11547T","-11548T","-11549T","-11550C","-11551T","-11552C","-11553C","-11554T","-11555C","-11556G","-11557T","-11558T","-11559T","-11560G","-11561T","-11562C","-11563A","-11564A","-11565T","-11566C","-11567A","-11568T","-11569G","-11570T","-11571T","-11572A","-11573A","-11574T","-11575G","-11576T","-11577C","-11578T","-11579T","-11580T","-11581A","-11582A","-11583G","-11584A","-11585T","-11586A","-11587A","-11588G","-11589G","-11590T","-11591A","-11592G","-11593A","-11594C","-11595A","-11596A","-11597A","-11598T","-11599G","-11600T","-11601T","-11602T","-11603A","-11604T","-11605A","-11606G","-11607T","-11608A","-11609C","-11610T","-11611A","-11612A","-11613G","-11614A","-11615A","-11616T","-11617T","-11618G","-11619G","-11620G","-11621C","-11622A","-11623A","-11624A","-11625C","-11626A","-11627T","-11628A","-11629A","-11630G","-11631A","-11632C","-11633A","-11634T","-11635G","-11636T","-11637C","-11638A","-11639C","-11640A","-11641A","-11642A","-11643G","-11644A","-11645C","-11646C","-11647C","-11648T","-11649T","-11650T","-11651T","-11652T","-11653G","-11654T","-11655A","-11656T","-11657G","-11658T","-11659A","-11660T","-11661A","-11662A","-11663G","-11664T","-11665G","-11666T","-11667A","-11668G","-11669A","-11670A","-11671A","-11672T","-11673T","-11674A","-11675T","-11676A","-11677A","-11678C","-11679A","-11680T","-11681C","-11682C","-11683A","-11684T","-11685A","-11686G","-11687T","-11688T","-11689G","-11690G","-11691A","-11692T","-11693T","-11694C","-11695A","-11696C","-11697A","-11698T","-11699A","-11700G","-11701G","-11702T","-11703G","-11704T","-11705C","-11706C","-11707A","-11708A","-11709T","-11710C","-11711G","-11712G","-11713G","-11714A","-11715T","-11716C","-11717T","-11718C","-11719T","-11720C","-11721C","-11722A","-11723T","-11724C","-11725A","-11726T","-11727C","-11728G","-11729A","-11730G","-11731A","-11732T","-11733G","-11734A","-11735T","-11736T","-11737G","-11738A","-11739C","-11740G","-11741G","-11742C","-11743A","-11744T","-11745C","-11746T","-11747C","-11748C","-11749C","-11750C","-11751C","-11752T","-11753T","-11754C","-11755C","-11756T","-11757T","-11758T","-11759T","-11760T","-11761T","-11762A","-11763G","-11764T","-11765A","-11766G","-11767A","-11768T","-11769A","-11770T","-11771T","-11772T","-11773C","-11774A","-11775T","-11776C","-11777G","-11778T","-11779G","-11780T","-11781A","-11782A","-11783G","-11784A","-11785A","-11786T","-11787C","-11788A","-11789A","-11790T","-11791A","-11792T","-11793T","-11794A","-11795A","-11796T","-11797A","-11798T","-11799T","-11800T","-11801C","-11802T","-11803A","-11804A","-11805A","-11806G","-11807T","-11808A","-11809T","-11810C","-11811T","-11812G","-11813T","-11814G","-11815T","-11816A","-11817T","-11818A","-11819G","-11820C","-11821C","-11822T","-11823C","-11824T","-11825T","-11826T","-11827A","-11828T","-11829T","-11830T","-11831A","-11832C","-11833C","-11834A","-11835C","-11836A","-11837G","-11838C","-11839T","-11840C","-11841C","-11842A","-11843T","-11844A","-11845T","-11846T","-11847C","-11848C","-11849A","-11850A","-11851C","-11852A","-11853T","-11854G","-11855C","-11856A","-11857T","-11858T","-11859C","-11860C","-11861A","-11862C","-11863T","-11864A","-11865G","-11866A","-11867G","-11868G","-11869G","-11870A","-11871T","-11872A","-11873T","-11874C","-11875G","-11876A","-11877T","-11878A","-11879T","-11880C","-11881G","-11882C","-11883C","-11884G","-11885A","-11886A","-11887T","-11888G","-11889T","-11890C","-11891A","-11892T","-11893A","-11894T","-11895A","-11896C","-11897T","-11898C","-11899A","-11900A","-11901T","-11902T","-11903A","-11904G","-11905T","-11906A","-11907T","-11908A","-11909T","-11910G","-11911T","-11912T","-11913G","-11914G","-11915A","-11916G","-11917G","-11918A","-11919C","-11920A","-11921T","-11922C","-11923C","-11924G","-11925A","-11926G","-11927T","-11928T","-11929C","-11930A","-11931T","-11932T","-11933G","-11934T","-11935T","-11936T","-11937T","-11938C","-11939A","-11940A","-11941T","-11942A","-11943T","-11944C","-11945A","-11946A","-11947A","-11948G","-11949A","-11950G","-11951A","-11952T","-11953G","-11954G","-11955T","-11956T","-11957T","-11958C","-11959C","-11960T","-11961T","-11962A","-11963T","-11964C","-11965A","-11966T","-11967T","-11968T","-11969C","-11970T","-11971C","-11972C","-11973A","-11974T","-11975A","-11976G","-11977T","-11978G","-11979G","-11980T","-11981A","-11982C","-11983A","-11984A","-11985T","-11986A","-11987C","-11988T","-11989A","-11990C","-11991A","-11992C","-11993A","-11994T","-11995T","-11996A","-11997T","-11998T","-11999C","-12000C","-12001G","-12002T","-12003A","-12004C","-12005G","-12006G","-12007C","-12008T","-12009T","-12010T","-12011C","-12012C","-12013A","-12014T","-12015T","-12016C","-12017T","-12018C","-12019C","-12020A","-12021A","-12022A","-12023A","-12024A","-12025C","-12026A","-12027A","-12028T","-12029T","-12030T","-12031T","-12032A","-12033C","-12034C","-12035A","-12036A","-12037A","-12038T","-12039C","-12040T","-12041A","-12042A","-12043A","-12044T","-12045C","-12046T","-12047A","-12048C","-12049A","-12050T","-12051C","-12052T","-12053T","-12054T","-12055A","-12056T","-12057T","-12058G","-12059T","-12060A","-12061T","-12062C","-12063T","-12064A","-12065T","-12066A","-12067A","-12068T","-12069C","-12070A","-12071C","-12072T","-12073A","-12074T","-12075T","-12076T","-12077A","-12078G","-12079A","-12080T","-12081A","-12082A","-12083T","-12084C","-12085A","-12086G","-12087C","-12088C","-12089A","-12090T","-12091A","-12092A","-12093T","-12094T","-12095C","-12096C","-12097T","-12098C","-12099G","-12100A","-12101G","-12102T","-12103G","-12104C","-12105A","-12106A","-12107C","-12108A","-12109T","-12110G","-12111T","-12112T","-12113A","-12114G","-12115A","-12116T","-12117C","-12118G","-12119T","-12120C","-12121T","-12122A","-12123T","-12124A","-12125T","-12126A","-12127T","-12128G","-12129A","-12130A","-12131T","-12132A","-12133A","-12134G","-12135C","-12136C","-12137G","-12138T","-12139G","-12140T","-12141T","-12142A","-12143T","-12144C","-12145T","-12146A","-12147T","-12148T","-12149C","-12150C","-12151T","-12152T","-12153T","-12154C","-12155A","-12156T","-12157T","-12158A","-12159A","-12160C","-12161A","-12162A","-12163T","-12164T","-12165T","-12166A","-12167A","-12168C","-12169G","-12170A","-12171T","-12172G","-12173T","-12174C","-12175T","-12176A","-12177T","-12178A","-12179T","-12180C","-12181T","-12182A","-12183T","-12184A","-12185T","-12186G","-12187A","-12188G","-12189A","-12190T","-12191G","-12192A","-12193C","-12194T","-12195T","-12196A","-12197A","-12198T","-12199A","-12200T","-12201A","-12202A","-12203T","-12204A","-12205T","-12206T","-12207G","-12208A","-12209A","-12210G","-12211A","-12212G","-12213C","-12214T","-12215G","-12216T","-12217A","-12218C","-12219A","-12220A","-12221T","-12222A","-12223G","-12224T","-12225T","-12226T","-12227T","-12228T","-12229A","-12230T","-12231C","-12232T","-12233A","-12234T","-12235A","-12236G","-12237A","-12238A","G40242A","C40335T","C127609T","G139582A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG023":["-222S","-223I","-224D","-225K","-226N","-227Y","-228C","-229T","-230A","-231L","-232Q","-233Y","-234Y","-235I","-236K","-237S","-238S","-239H","-240I","-241D","-242I","-243D","-244I","-245V","-246K","-247L","-248L","-249M","-250K","-251G","-252I","-253D","-254N","-255T","-256A","-257Y","-258S","-259Y","-260I","-261D","-262D","-263L","-264T","-265C","-266C","-267T","-268R","-269G","-270I","-271M","-272A","-273D","-274Y","-275L","-276N","-277S","-278D","-279Y","-280R","-281Y","-282N","-283K","-284D","-285V","-286D","-287L","-288D","-289L","-290V","-291K","-292L","-293F","-294L","-295E","-296N","-297G","-298K","-299P","-300Y","-301G","-302I","-303M","-304C","-305S","-306I","-307V","-308P","-309L","-310W","-311R","-312N","-313D","-314K","-315E","-316T","-317I","-318S","-319L","-320I","-321L","-322K","-323T","-324M","-325N","-326S","-327D","-328V","-329L","-330Q","-331H","-332I","-333L","-334I","-335E","-336Y","-337M","-338T","-339F","-340G","-341D","-342I","-343D","-344I","-345P","-346L","-347V","-348E","-349C","-350M","-351L","-352E","-353Y","-354G","-355A","-356V","-357V","-358N","-359K","-360E","-361A","-362I","-363H","-364R","-365Y","-366F","-367R","-368N","-369I","-370N","-371I","-372D","-373S","-374Y","-375T","-376M","-377K","-378Y","-379L","-380L","-381K","-382K","-383E","-384G","-385G","-386D","-387A","-388V","-389N","-390H","-391L","-392D","-393D","-394G","-395E","-396I","-397P","-398I","-399G","-400H","-401L","-402C","-403E","-404S","-405N","-406Y","-407G","-408C","-409Y","-410N","-411F","-412Y","-413T","-414Y","-415T","-416Y","-417K","-418K","-419G","-420L","-421C","-422D","-423M","-424S","-425Y","-426V","-427C","-428P","-429I","-430L","-431S","-432T","-433I","-434N","-435I","-436C","-437L","-438P","-439Y","-440L","-441K","-442D","-443I","-444N","-445M","-446I","-447D","-448K","-449R","-450G","-451E","-452T","-453L","-454L","-455H","-456K","-457A","-458V","-459R","-460Y","-461N","-462K","-463Q","-464S","-465L","-466V","-467S","-468L","-469L","-470L","-471E","-472S","-473G","-474S","-475D","-476V","-477N","-478I","-479R","-480S","-481N","-482N","-483G","-484Y","-485T","-486C","-487I","-488T","-489I","-490A","-491I","-492N","-493E","-494S","-495R","-496N","-497I","-498E","-499L","-500L","-501K","-502M","-503L","-504L","-505C","-506H","-507K","-508P","-509T","-510L","-511D","-512C","-513V","-514I","-515D","-516S","-517L","-518S","-519E","-520V","-521S","-522N","-523I","-524V","-525D"],"OPG058":["E34K"]},"labels":{"aa":"OPG023: -222S, -223I, -224D, -225K, -226N, -227Y, -228C, -229T, -230A, -231L, -232Q, -233Y, -234Y, -235I, -236K, -237S, -238S, -239H, -240I, -241D, -242I, -243D, -244I, -245V, -246K, -247L, -248L, -249M, -250K, -251G, -252I, -253D, -254N, -255T, -256A, -257Y, -258S, -259Y, -260I, -261D, -262D, -263L, -264T, -265C, -266C, -267T, -268R, -269G, -270I, -271M, -272A, -273D, -274Y, -275L, -276N, -277S, -278D, -279Y, -280R, -281Y, -282N, -283K, -284D, -285V, -286D, -287L, -288D, -289L, -290V, -291K, -292L, -293F, -294L, -295E, -296N, -297G, -298K, -299P, -300Y, -301G, -302I, -303M, -304C, -305S, -306I, -307V, -308P, -309L, -310W, -311R, -312N, -313D, -314K, -315E, -316T, -317I, -318S, -319L, -320I, -321L, -322K, -323T, -324M, -325N, -326S, -327D, -328V, -329L, -330Q, -331H, -332I, -333L, -334I, -335E, -336Y, -337M, -338T, -339F, -340G, -341D, -342I, -343D, -344I, -345P, -346L, -347V, -348E, -349C, -350M, -351L, -352E, -353Y, -354G, -355A, -356V, -357V, -358N, -359K, -360E, -361A, -362I, -363H, -364R, -365Y, -366F, -367R, -368N, -369I, -370N, -371I, -372D, -373S, -374Y, -375T, -376M, -377K, -378Y, -379L, -380L, -381K, -382K, -383E, -384G, -385G, -386D, -387A, -388V, -389N, -390H, -391L, -392D, -393D, -394G, -395E, -396I, -397P, -398I, -399G, -400H, -401L, -402C, -403E, -404S, -405N, -406Y, -407G, -408C, -409Y, -410N, -411F, -412Y, -413T, -414Y, -415T, -416Y, -417K, -418K, -419G, -420L, -421C, -422D, -423M, -424S, -425Y, -426V, -427C, -428P, -429I, -430L, -431S, -432T, -433I, -434N, -435I, -436C, -437L, -438P, -439Y, -440L, -441K, -442D, -443I, -444N, -445M, -446I, -447D, -448K, -449R, -450G, -451E, -452T, -453L, -454L, -455H, -456K, -457A, -458V, -459R, -460Y, -461N, -462K, -463Q, -464S, -465L, -466V, -467S, -468L, -469L, -470L, -471E, -472S, -473G, -474S, -475D, -476V, -477N, -478I, -479R, -480S, -481N, -482N, -483G, -484Y, -485T, -486C, -487I, -488T, -489I, -490A, -491I, -492N, -493E, -494S, -495R, -496N, -497I, -498E, -499L, -500L, -501K, -502M, -503L, -504L, -505C, -506H, -507K, -508P, -509T, -510L, -511D, -512C, -513V, -514I, -515D, -516S, -517L, -518S, -519E, -520V, -521S, -522N, -523I, -524V, -525D; OPG058: E34K"}},"children":[{"name":"OP431400","node_attrs":{"div":10,"accession":"OP431400","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-22751-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP431400/2022-08-17"},"date":{"value":"2022-08-17"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G47482A","C60062T","G125388A"],"OPG080":["E653K"],"OPG145":["R481H"]},"labels":{"aa":"OPG080: E653K; OPG145: R481H"}}},{"name":"OP390175","node_attrs":{"div":7,"accession":"OP390175","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"BOL-UNIMOL-MPX-292803-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"strain_display":{"value":"Colombia/OP390175/2022-08-02"},"date":{"value":"2022-08-02"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{}}},{"name":"OP819950","node_attrs":{"div":9,"accession":"OP819950","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MET_INS_MPX_0956_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP819950/2022-10-12"},"date":{"value":"2022-10-12"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G144284A","C171808T","-180517A","-180518A","-180519T","-180520G","-180521A","-180522C","-180523G","-180524A","-180525T","-180526A","-180527T","-180528A","-180529C","-180530G","-180531G","-180532A","-180533T","-180534T","G196973-","A196974-","A196975-"],"OPG165":["D257N"],"OPG199":["S274L"]},"labels":{"aa":"OPG165: D257N; OPG199: S274L"}}},{"name":"OP693654","node_attrs":{"div":7,"accession":"OP693654","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"DC_INS_MPX_0722_L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP693654/2022-08-23"},"date":{"value":"2022-08-23"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A2840-","T2841-","C2842-"]}}},{"name":"NODE_0000126","node_attrs":{"div":8,"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C21324T"]}},"children":[{"name":"OP623592","node_attrs":{"div":10,"accession":"OP623592","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"BOL-UNIMOL-MPX-293165-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"strain_display":{"value":"Colombia/OP623592/2022-08-09"},"date":{"value":"2022-08-09"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C18213T","G141921A"],"OPG031":["E206K"]},"labels":{"aa":"OPG031: E206K"}}},{"name":"OP837479","node_attrs":{"div":11,"accession":"OP837479","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"DC_INS_MPX_1024_L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP837479/2022-09-20"},"date":{"value":"2022-09-20"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","G68296A","C144166T","-180517A","-180518A","-180519T","-180520G","-180521A","-180522C","-180523G","-180524A","-180525T","-180526A","-180527T","-180528A","-180529C","-180530G","-180531G","-180532A","-180533T","-180534T","C181495T"],"OPG085":["S79L"],"OPG210":["S47L"]},"labels":{"aa":"OPG085: S79L; OPG210: S47L"}}},{"name":"OR035721","node_attrs":{"div":9,"accession":"OR035721","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.15"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_115"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035721/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-180517A","-180518A","-180519T","-180520G","-180521A","-180522C","-180523G","-180524A","-180525T","-180526A","-180527T","-180528A","-180529C","-180530G","-180531G","-180532A","-180533T","-180534T","G180556A","T196712-","A196713-","T196714-"]}}}]}]}]},{"name":"NODE_0000127","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C112408T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG131":["L157F"]},"labels":{"aa":"OPG131: L157F"}},"children":[{"name":"OQ672571","node_attrs":{"div":3,"accession":"OQ672571","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"19012023_anal"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672571/2023-01-19"},"date":{"value":"2023-01-19"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G69989A","C117978T","T145510-","T145511-","A145512-","C145513-","T145514-","T145515-","A145516-","A145517-","T145518-","A145519-","G145520-","A145521-","T145522-","T145523-","A145524-","T145525-","G145526-","T145527-","T146786-","A146787-","T146788-","T146789-","G146790-","T146791-","T146792-","A146793-","T146794-","C146795-","G146796-","T146797-","A146798-","A146799-","T146800-","T146801-","G146802-","G146803-","A146804-","A146805-","A146806-","A146807-","T146808-","T146809-","G146810-","G146811-","T146812-","A146813-","T146814-","T146815-","C146816-","A146817-","A146818-","G146819-","T146820-","G146821-","A146822-","G146823-","C146824-","T146825-","G146826-","G146827-","A146828-","T146829-","T146830-","A146831-","T146832-","G146833-","T146834-","G146835-","A146836-","G146837-","T146838-","A146839-","T146840-","T146841-","G146842-","G146843-","A146844-","T146845-","T146846-","G146847-","T146848-","A146849-","T146850-","A146851-","T146852-","T146853-","T146854-","T146855-","A146856-","T146857-","T146858-","T146859-","T146860-","A146861-","T146862-","A146863-","T146864-","T146865-","T146866-","T146867-","A146868-","T146869-","A146870-","T146871-","T146872-","T146873-","T146874-","A146875-","T146876-","A146877-","T146878-","T146879-","T146880-","T146881-","A146882-","T146883-","T146884-","T146885-","T146886-","A146887-","T146888-","A146889-","T146890-","T146891-","T146892-","T146893-","A146894-","T146895-","A146896-","T146897-","T146898-","T146899-","T146900-","A146901-","T146902-","T146903-","T146904-","T146905-","A146906-","T146907-","A146908-","T146909-","T146910-","T146911-","T146912-","G146913-","T146914-","A146915-","G146916-","T146917-","A146918-","A146919-","G146920-","A146921-","A146922-","T146923-","A146924-","G146925-","A146926-","A146927-","T146928-","G146929-","C146930-","T146931-","A146932-","A146933-","T146934-","G146935-","T146936-","C146937-","A146938-","A146939-","G146940-","T146941-","T146942-","T146943-","A146944-","T146945-","T146946-","C146947-","G146948-","A146949-","A146950-","T146951-","A146952-","G146953-","A146954-","T146955-","G146956-","T146957-","C146958-","T146959-","T146960-","A146961-","T146962-","T146963-","A146964-","A146965-","A146966-","A146967-","A146968-","A146969-","C146970-","A146971-","T146972-","A146973-","T146974-","A146975-","T146976-","A146977-","A146978-","T146979-","A146980-","A146981-","A146982-","T146983-","A146984-","A146985-","C146986-","A146987-","A146988-","T146989-","G146990-","G146991-","C146992-","T146993-","G146994-","A146995-","A146996-","T146997-","G146998-","G146999-","C147000-","A147001-","T147002-","A147003-","A147004-","A147005-","A147006-","T147007-","T147008-","A147009-","T147010-","C147011-","G147012-","A147013-","G147014-","G147015-","A147016-","T147017-","A147018-","T147019-","C147020-","T147021-","C147022-","A147023-","A147024-","A147025-","A147026-","A147027-","T169726-","A169727-"],"OPG089":["A42T"],"OPG136":["R537K"],"OPG197":["T20-"]},"labels":{"aa":"OPG089: A42T; OPG136: R537K; OPG197: T20-"}}},{"name":"NODE_0000128","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G6878A","C40894T","C67724T","C145201-","C145202-","A145203-","T145204-","T145205-","T145206-","A145207-","T180382-","A180383-","T180384-","T180385-","A180386-","C180387-","A180388-","A180389-","A180390-","T180391-","A180392-","G180393-","T180394-","A180395-","T180396-","A180397-","G180398-","C180399-","A180400-","T180401-","A180402-","A180403-","A180404-","C180405-","T180406-","A180407-","A180408-","A180409-","G180410-","T180411-","C180412-","G180413-","A180414-","T180415-","A180416-","C180417-","A180418-","T180419-","A180420-","C180421-","A180422-","T180423-","T180424-","A180425-","A180426-","A180427-","A180428-","C180429-","T180430-","T180431-","A180432-","A180433-","A180434-","T180435-","A180436-","A180437-","T180438-","A180439-","A180440-","T180441-","G180442-","T180443-","A180444-","A180445-","T180446-","T180447-","T180448-","A180449-","C180450-","A180451-","A180452-","T180453-","T180454-","A180455-","A180456-","T180457-","A180458-","G180459-","T180460-","A180461-","T180462-","A180463-","A180464-","A180465-","C180466-","T180467-","A180468-","A180469-","A180470-","A180471-","A180472-","A180473-","A180474-","T180475-","T180476-","A180477-","A180478-","A180479-","A180480-","A180481-","A180482-","T180483-","T180484-","A180485-","A180486-","A180487-","A180488-","A180489-","C180490-","A180491-","A180492-","T180493-","A180494-","T180495-","C180496-","A180497-","T180498-","T180499-","A180500-","T180501-","T180502-","A180503-","T180504-","A180505-","A180506-","G180507-","T180508-","A180509-","A180510-","T180511-","A180512-","T180513-","C180514-","A180515-","A180516-","A180535-","A180536-","T180537-","A180538-","G180539-","C180540-","G180541-","T180542-","A180543-","T180544-","C180545-","T180546-","T180547-","A180548-","T180549-","A180550-","T180551-","T180552-","C180553-","G180554-","T180555-","G180556-","A180557-","C180558-","T180559-","T180560-","C180561-","A180562-","T180563-","C180564-","C180565-","A180566-","T180567-","C180568-","G180569-","C180570-","T180571-","A180572-","G180573-","T180574-","C180575-","C180576-","A180577-","C180578-","T180579-","T180580-","T180581-","A180582-","C180583-","A180584-","T180585-","T180586-","C180587-","C180588-","C180589-","G180590-","T180591-","T180592-","A180593-","T180594-","T180595-","C180596-","C180597-","G180598-","C180599-","C180600-","C180601-","A180602-","T180603-","T180604-","T180605-","C180606-","G180607-","G180608-","A180609-","A180610-","G180611-","A180612-","T180613-","A180614-","A180615-","A180616-","T180617-","C180618-","G180619-","T180620-","T180621-","C180622-","A180623-","A180624-","T180625-","A180626-","G180627-","T180628-","G180629-","T180630-","A180631-","G180632-","A180633-","G180634-","G180635-","T180636-","A180637-","T180638-","T180639-","A180640-","G180641-","T180642-","T180643-","T180644-","C180645-","T180646-","T180647-","T180648-","G180649-","T180650-","T180651-","T180652-","C180653-","C180654-","C180655-","G180656-","A180657-","T180658-","G180659-","A180660-","C180661-","C180662-","A180663-","A180664-","A180665-","A180666-","A180667-","G180668-","A180669-","C180670-","T180671-","A180672-","T180673-","A180674-","C180675-","A180676-","G180677-","T180678-","A180679-","A180680-","C180681-","T180682-","T180683-","C180684-","T180685-","C180686-","A180687-","G180688-","T180689-","T180690-","C180691-","A180692-","A180693-","T180694-","A180695-","A180696-","C180697-","T180698-","A180699-","C180700-","A180701-","C180702-","T180703-","A180704-","T180705-","C180706-","G180707-","G180708-","T180709-","A180710-","C180711-","C180712-","A180713-","A180714-","A180715-","G180716-","A180717-","C180718-","T180719-","G180720-","G180721-","A180722-","C180723-","T180724-","A180725-","T180726-","C180727-","A180728-","A180729-","C180730-","G180731-","T180732-","A180733-","C180734-","T180735-","A180736-","T180737-","C180738-"],"OPG060":["G97R"],"OPG085":["E270K"],"OPG167":["K68-","W69-"]},"labels":{"aa":"OPG060: G97R; OPG085: E270K; OPG167: K68-, W69-"}},"children":[{"name":"OQ672575","node_attrs":{"div":6,"accession":"OQ672575","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"02022023_gluteal"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672575/2023-02-02"},"date":{"value":"2023-02-02"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["A125538G","G152986A"],"OPG180":["E99K"]},"labels":{"aa":"OPG180: E99K"}}},{"name":"OQ672573","node_attrs":{"div":5,"accession":"OQ672573","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"26012023_neck"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672573/2023-01-26"},"date":{"value":"2023-01-26"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","T2653-","T2654-","T47709-","G47710-","T47742-","T47743-","A47744-","G47745-","G47746-","A47747-","C47748-","T47749-","A47750-","C47751-","T47752-","A47753-","C47754-","T47755-","C47756-","T47757-","A47758-","G47759-","A47760-","A47761-","G47762-","A47763-","T47764-","A47765-","T47766-","A47767-","G47768-","C47769-","A47770-","C47771-","C47772-","A47773-","T47774-","C47775-","T47776-","A47777-","T47778-","T47779-","C47780-","C47781-","A47782-","A47783-","A47784-","T47785-","A47786-","A47787-","T47788-","C47789-","A47790-","G47791-","A47792-","A47793-","A47794-","A47795-","C47796-","T47797-","T47798-","A47799-","T47800-","A47801-","A47802-","A47803-","C47804-","T47805-","A47806-","T47807-","T47808-","C47809-","T47810-","C47811-","G47812-","G47813-","A47814-","C47815-","A47816-","T47817-","T47818-","T47819-","C47820-","A47821-","G47822-","T47823-","C47824-","A47825-","T47826-","T47827-","G47828-","G47829-","C47830-","A47831-","A47960-","T47961-","G47962-","T47963-","A47964-","T47965-","G47966-","C47967-","C47968-","T47969-","G47970-","T47971-","T47972-","C47973-","G47974-","T47975-","A47976-","T47977-","G47978-","C47979-","C47980-","A48037-","G48038-","T48039-","C48069-","A48070-","T48071-","C48072-","A48113-","T48114-","A48115-","G48116-","T48117-","A48118-","C48176-","A48177-","T48178-","A48179-","G48180-","A48181-","T48182-","A48183-","A48184-","C48185-","T48186-","C48187-","T48188-","C48189-","T48190-","T48191-","C48192-","T48193-","A48194-","T48195-","A48196-","A48197-","A48198-","A48199-","A48200-","A48201-","T48202-","G48203-","G48204-","A48205-","T48206-","T48207-","T48208-","T48209-","A48210-","T48211-","T48212-","C48213-","G48214-","T48215-","A48216-","G48217-","A48218-","A48219-","A48220-","G48221-","T48222-","A48223-","T48224-","C48225-","T48226-","T48227-","A48228-","T48229-","A48230-","T48231-","A48232-","C48233-","A48234-","C48235-","A48236-","G48237-","T48238-","A48239-","G48240-","A48241-","A48289-","T48290-","A48330-","G48331-","C48332-","A48333-","A48334-","T48335-","T48336-","T48337-","T48338-","C48339-","T48366-","G48387-","T48388-","T48389-","T48390-","T48391-","C48392-","A48393-","T48394-","A48395-","C48396-","A48397-","C48435-","G48436-","A48437-","C48438-","A48439-","C48440-","G48441-","C48442-","A48443-","T48444-","T48445-","T48446-","G48447-","A48448-","T48449-","G48450-","C48451-","A48452-","A48571-","A48572-","T48573-","A48574-","C48575-","A48576-","T48577-","G48578-","G48579-","A48580-","C48581-","G48582-","A48583-","A48584-","T48585-","T48586-","A48587-","G48588-","G48589-","A48590-","G48591-","A48592-","A48593-","C48594-","T48595-","T48596-","A48597-","T48598-","A48599-","G48600-","G48601-","C48602-","G48603-","T48604-","A48605-","A48606-","A48607-","T48608-","T48609-","A48610-","T48611-","G48612-","A48613-","C48614-","T48615-","T48616-","A48617-","G48618-","T48619-","C48648-","C48649-","C48650-","A48651-","T48652-","C48653-","A48654-","A48655-","A48656-","G48657-","A48658-","T48659-","A48660-","T48661-","G48662-","G48663-","A48664-","A48665-","A48666-","T48667-","C48668-","A48669-","T48670-","T48671-","T48672-","T48673-","T48674-","A48759-","A48760-","A48761-","G48762-","A48763-","T48764-","A48765-","C48766-","A48767-","G48768-","G48769-","C48770-","A48771-","T48772-","A48773-","G48774-","G48780-","C48781-","G48782-","G48783-","A48784-","T48785-","A48786-","A48787-","T48788-","G48789-","A48790-","T48791-","A48792-","G48793-","A48794-","C48823A","C48837-","A48838-","T48839-","A48840-","G48841-","C48842-","A48843-","A48844-","T48845-","C48846-","T48847-","A48848-","A48849-","C48850-","A48851-","G48852-","A48853-","A48854-","A48855-","C48856-","G48857-","T48858-","T48859-","T48860-","A48861-","G48862-","G48863-","G48864-","A48865-","T48866-","T48867-","A48868-","T48869-","A48870-","T48871-","C48872-","T48873-","T48874-","T48875-","C48876-","C48877-","C48878-","G48879-","G48880-","A48881-","G48882-","A48883-","T48884-","A48885-","A48886-","G48887-","A48888-","C48889-","A48924-","A48925-","T48926-","G48927-","A48928-","T48929-","G48930-","C48931-","G48932-","G48933-","A48934-","A48987-","T48988-","A48989-","T48990-","A48991-","C48992-","T48993-","C48994-","T48995-","G48996-","A48997-","G48998-","A48999-","T49000-","A49001-","A49002-","A49003-","A49004-","C49005-","A49006-","G49007-","G49008-","G49009-","A49010-","C49011-","G49012-","C49013-","G49014-","T49015-","T49016-","A49017-","A49018-","T49019-","A49020-","A49021-","A49022-","A49023-","A49024-","C49025-","A49026-","T49027-","G49028-","C49029-","T49030-","T49031-","A49032-","A49033-","G49034-","T49035-","T49036-","A49037-","G49038-","T49039-","T49040-","T49041-","A49042-","T49043-","A49044-","T49045-","C49046-","T49047-","T49048-","T49049-","G49050-","A49051-","G49052-","C49053-","C49054-","T49157-","A49158-","T49159-","T49160-","A49161-","G49162-","T49163-","T49164-","T49165-","T49166-","T49167-","A49168-","C49169-","A49170-","A49171-","A49172-","G49173-","C49174-","T49175-","A49176-","A49177-","T49178-","T49179-","T49180-","T49181-","A49182-","T49183-","T49184-","A49185-","A49186-","C49187-","G49188-","G49189-","T49190-","A49191-","A49192-","T49193-","A49194-","C49195-","A49196-","T49197-","T49198-","T49199-","A49200-","T49201-","T49202-","A49203-","G49204-","T49205-","G49206-","A49207-","T49208-","A49209-","G49210-","A49211-","A49212-","C49213-","G49214-","T49215-","T49216-","T49217-","A49218-","A49219-","C49220-","G49221-","A49222-","T49223-","G49224-","A49225-","C49226-","T49227-","T49228-","A49229-","T49230-","T49231-","C49232-","A49233-","G49234-","A49235-","G49236-","T49237-","T49238-","G49239-","T49240-","T49241-","G49242-","T49243-","T49244-","C49245-","A49246-","A49247-","A49248-","T49249-","A49250-","G49251-","A49252-","T49253-","C49254-","C49255-","C49256-","G49257-","A49258-","A49259-","T49260-","A49261-","T49262-","T49263-","T49264-","C49265-","G49266-","A49267-","T49268-","A49269-","A49270-","T49271-","G49272-","A49273-","A49274-","C49275-","G49276-","A49277-","A49278-","T49279-","T49280-","A49281-","T49282-","G49283-","T49284-","C49285-","T49286-","T49287-","T49288-","A49289-","T49290-","T49291-","C49292-","T49293-","A49294-","T49295-","A49296-","C49297-","G49298-","A49299-","G49300-","T49301-","G49302-","C49303-","T49304-","G49305-","C49306-","G49307-","G49308-","A49309-","C49310-","A49311-","T49312-","T49313-","A49314-","A49315-","A49316-","C49317-","G49318-","A49319-","T49320-","T49321-","T49322-","G49323-","A49324-","T49325-","G49326-","A49327-","G49328-","T49329-","T49330-","A49331-","G49332-","A49333-","T49334-","A49335-","T49336-","T49337-","A49338-","A49339-","T49340-","A49341-","A49342-","C49343-","A49344-","G49345-","T49346-","T49347-","A49348-","T49349-","A49350-","T49351-","A49352-","T49353-","C49354-","T49355-","A49356-","A49357-","T49358-","A49407-","A49408-","G49409-","A49410-","A49411-","G49412-","T49413-","G49414-","T49415-","C49416-","A49417-","A49418-","A49419-","T49420-","T49473-","T49474-","G49475-","C49476-","A49477-","C49478-","G49479-","A49480-","G49481-","T49482-","C49483-","G49484-","G49485-","A49486-","T49487-","C49488-","C49489-","C49490-","A49491-","T49492-","G49493-","G49494-","T49495-","C49496-","A49497-","T49498-","A49499-","G49500-","A49501-","G49502-","A49503-","A49504-","C49505-","G49506-","G49507-","A49508-","A49509-","T49510-","A49511-","C49512-","T49513-","A49514-","A49515-","A49516-","G49517-","A49518-","A49519-","A49520-","C49521-","T49522-","G49523-","T49524-","C49525-","A49526-","T49527-","C49528-","T49529-","A49530-","T49531-","A49532-","A49533-","A49534-","A49535-","T49536-","C49537-","C49538-","A49539-","A49540-","G49541-","A49542-","G49543-","T49544-","A49545-","G49546-","A49547-","C49548-","G49549-","G49550-","C49551-","T49552-","G49553-","A49554-","A49555-","C49556-","T49557-","T49558-","G49559-","T49560-","T49561-","T49562-","A49563-","G49564-","C49565-","A49566-","A49567-","A49568-","A49569-","A49570-","C49571-","A49572-","T49573-","T49574-","T49575-","T49576-","A49577-","A49578-","A49579-","A49580-","T49581-","A49582-","T49583-","T49584-","A49585-","T49586-","T49587-","T49588-","A49589-","G49590-","A49591-","C49592-","G49593-","G49594-","A49595-","C49596-","A49597-","A49598-","T49599-","T49600-","G49601-","G49602-","C49603-","T49604-","C49605-","G49606-","T49607-","C49608-","T49609-","A49610-","G49611-","G49612-","T49613-","C49614-","T49615-","T49616-","G49617-","T49618-","G49619-","T49620-","T49621-","A49622-","G49623-","A49624-","T49625-","G49626-","A49627-","T49628-","T49629-","A49630-","T49631-","A49632-","A49633-","A49634-","G49635-","G49636-","A49637-","G49638-","A49639-","C49640-","T49641-","T49642-","A49643-","T49644-","T49645-","A49646-","G49647-","T49648-","T49649-","A49650-","A49651-","A49652-","A49653-","T49654-","G49655-","A49656-","T49657-","A49658-","A49659-","A49660-","C49661-","C49662-","A49663-","T49664-","C49665-","T49666-","C49667-","A49668-","A49669-","A49670-","T49671-","C49672-","T49673-","G49674-","T49675-","G49676-","G49677-","A49678-","G49679-","G49680-","A49681-","T49682-","G49683-","T49684-","A49685-","T49686-","C49687-","C49688-","G49689-","C49690-","A49691-","T49692-","T49693-","C49694-","G49695-","T49696-","T49697-","A49698-","G49699-","A49700-","T49701-","T49702-","T49703-","T49704-","C49705-","T49706-","A49707-","C49708-","A49709-","A62259-","G62260-","T62261-","T62262-","A62263-","C62305-","A62306-","A62307-","A62308-","G62309-","A62328-","G62329-","T62330-","T62331-","G62332-","T62333-","A62334-","T62335-","A62336-","C62337-","T62338-","G62339-","A62340-","G62341-","A62342-","A62343-","T62344-","T62345-","G62346-","A62347-","C62348-","G62349-","T62373-","T62374-","T62375-","C62376-","T62377-","A62412-","C62413-","T62414-","A62415-","G62416-","A62417-","C62418-","T62419-","T62420-","G62421-","A62422-","A62433-","G62434-","T62435-","A62436-","T62437-","A62438-","G62439-","A62535-","C62536-","G62552-","A62553-","G62554-","G62571-","C62572-","T62573-","T62574-","C62575-","T62576-","A62577-","G62578-","A62601-","C62624-","T62625-","A62626-","T62627-","C62628-","A62646-","C62647-","T62648-","C62649-","G62650-","C62651-","G62652-","T62653-","T62654-","T62655-","A62656-","G62657-","A62658-","G62659-","G62660-","A62661-","G62662-","T62663-","G62664-","A62665-","A62666-","C62667-","G62668-","T62669-","C62670-","T62671-","T62672-","C62673-","G62758-","T62759-","G62760-","G62761-","A62762-","A62763-","T62764-","T62765-","G62766-","A62767-","A62768-","G62769-","A62770-","T62771-","T62772-","C62773-","T62774-","A62775-","A62776-","T62777-","G62778-","G62779-","A62780-","T62781-","G62782-","A62783-","T62784-","G62785-","T62786-","T62787-","C62788-","T62789-","A62790-","C62791-","C62792-","T62793-","A62794-","T62795-","T62796-","T62797-","C62798-","A62799-","T62800-","C62801-","C62802-","G62803-","A62804-","T62805-","C62820-","A62821-","A62822-","T62823-","T62856-","A62857-","G62858-","T62859-","C62860-","T62861-","C62862-","T62863-","C62864-","T62865-","T62866-","T62867-","C62868-","G62869-","G62870-","A62871-","A62892-","T62893-","A62894-","C62895-","G62896-","A62897-","G62898-","T62899-","C62900-","A62901-","T62902-","T62903-","A62904-","T62905-","A62906-","T62907-","A62908-","C62909-","T62910-","C62911-","C62912-","T62931-","T62949-","G62950-","G62951-","G62952-","A62953-","C62967-","G62968-","A62969-","T62970-","A62982-","T62983-","C62984-","C62985-","G62986-","G62987-","A62988-","A62989-","C62990-","A62991-","T62992-","T62993-","G62994-","G63024-","G63025-","T63026-","A63027-","A63028-","G63029-","A63030-","A63031-","C63032-","A63042-","T63075-","T63076-","G63077-","A63078-","G63079-","A63080-","C63081-","T63082-","T63083-","G63084-","A63085-","T63086-","A63102-","T63103-","T63104-","C63143-","G63144-","T63145-","C63146-","G63147-","A63148-","C63149-","G63150-","C63151-","C63152-","A63153-","T63168-","G63169-","G63170-","A63171-","G63172-","T63173-","A63174-","C63240-","T63241-","C63242-","G63243-","T63244-","A63245-","C63246-","G63247-","C63248-","C63258-","A63259-","T63260-","G63261-","A63262-","T63263-","C63264-","A63265-","A63266-","G63267-","A63268-","G63269-","T63270-","G63271-","A63272-","T63273-","T63274-","T63275-","G63276-","A63277-","G63278-","A63279-","A63280-","C63281-","A63282-","T63283-","C63284-","C63285-","T63286-","C63287-","C63288-","A63311-","C63312-","A63313-","G63314-","T63315-","A63330-","T63331-","A63332-","A63333-","A63348-","A63349-","T63369-","A63370-","A63371-","A63372-","G63373-","A63374-","T63375-","T63385-","C63386-","T63387-","A63388-","A63389-","C63390-","G63391-","G63392-","A63393-","G63394-","A63395-","C63396-","A63397-","A63398-","T63399-","T63400-","T63401-","T63402-","T63403-","T63404-","G63405-","G63406-","T63407-","A63408-","G63409-","G63410-","T63411-","T63412-","T63413-","T63414-","A63415-","G63416-","A63417-","G63418-","A63419-","C63420-","T63421-","T63422-","T63423-","G63424-","A63425-","A63426-","G63427-","C63428-","T63429-","A63430-","C63431-","T63432-","T63433-","G63434-","T63435-","T63436-","T63437-","A63438-","A63439-","C63440-","A63441-","A63442-","A63443-","G63444-","T63445-","T63446-","A63447-","T63448-","T63449-","C63450-","A63451-","T63452-","C63453-","G63454-","T63455-","C63456-","T133098-","T133099-","T133100-","T133101-","T133102-","C180739-","A180740-"],"OPG002":["D34-","N35-"],"OPG068":["S44-","N45-","F46-","P47-","Q48-","H49-","L56-","V63-","F64-","I65-","H66-","M67-","V68-","R69-","H80-","A81-","F82-","D83-","A84-","P85-","Y125-","M126-","D127-","E128-","L129-","G130-","E131-","L132-","I133-","G134-","V135-","N136-","Y137-","D138-","L139-","V140-","N242-","D243-","A244-","D245-","I263-","Y264-","S265-","E266-","I267-","K268-","Q269-","G270-","R271-","V272-","N273-","K274-","N275-","M276-","L277-","K278-","L279-","V280-","Y281-","I282-","F283-","E284-","P285-","I320-","S321-","F322-","Y323-","K324-","A325-","N326-","F327-","I328-","N329-","G330-","N331-","T332-","F333-","I334-","S335-","D336-","R337-","T338-","F339-","N340-","D341-","D342-","L343-","F344-","R345-","V346-","V347-","V348-","Q349-","I350-","D351-","P352-","E353-","Y354-","F355-","D356-","N357-","E358-","R359-","I360-","M361-","S362-","L363-","F364-","Y365-","T366-","S367-","A368-","A369-","D370-","I371-","K372-","R373-","F374-","D375-","E376-","L377-","D378-","I379-","N380-","N381-","S382-","Y383-","I384-","S385-","N386-","I387-","K403-","K404-","C405-","Q406-","I407-"],"OPG081":["T9-"],"OPG082":["S27-","L28-","Y41-","L47-","F48-","T49-","K50-","E56-","D57-","V58-","L59-","K60-","S61-","L62-","L63-","I64-","M65-","N154-","V155-","P156-","D157-","S158-","S162-","P168-","F169-","D170-","L211-","E212-","I213-","N214-","M215-","L216-","S217-","D218-","E219-","I220-","G221-","R222-","T223-","S224-","S225-","I226-","R227-","I228-","F229-","S231M","T232F","K261-","T262-","F263-","T264-","P265-","L266-","N267-","A268-","S269-","I276-","V277-","R293-","S294-","T300N","H301-","Y339-","T340-","K345-","S346-","S347-"]},"labels":{"aa":"OPG002: D34-, N35-; OPG068: S44-, N45-, F46-, P47-, Q48-, H49-, L56-, V63-, F64-, I65-, H66-, M67-, V68-, R69-, H80-, A81-, F82-, D83-, A84-, P85-, Y125-, M126-, D127-, E128-, L129-, G130-, E131-, L132-, I133-, G134-, V135-, N136-, Y137-, D138-, L139-, V140-, N242-, D243-, A244-, D245-, I263-, Y264-, S265-, E266-, I267-, K268-, Q269-, G270-, R271-, V272-, N273-, K274-, N275-, M276-, L277-, K278-, L279-, V280-, Y281-, I282-, F283-, E284-, P285-, I320-, S321-, F322-, Y323-, K324-, A325-, N326-, F327-, I328-, N329-, G330-, N331-, T332-, F333-, I334-, S335-, D336-, R337-, T338-, F339-, N340-, D341-, D342-, L343-, F344-, R345-, V346-, V347-, V348-, Q349-, I350-, D351-, P352-, E353-, Y354-, F355-, D356-, N357-, E358-, R359-, I360-, M361-, S362-, L363-, F364-, Y365-, T366-, S367-, A368-, A369-, D370-, I371-, K372-, R373-, F374-, D375-, E376-, L377-, D378-, I379-, N380-, N381-, S382-, Y383-, I384-, S385-, N386-, I387-, K403-, K404-, C405-, Q406-, I407-; OPG081: T9-; OPG082: S27-, L28-, Y41-, L47-, F48-, T49-, K50-, E56-, D57-, V58-, L59-, K60-, S61-, L62-, L63-, I64-, M65-, N154-, V155-, P156-, D157-, S158-, S162-, P168-, F169-, D170-, L211-, E212-, I213-, N214-, M215-, L216-, S217-, D218-, E219-, I220-, G221-, R222-, T223-, S224-, S225-, I226-, R227-, I228-, F229-, S231M, T232F, K261-, T262-, F263-, T264-, P265-, L266-, N267-, A268-, S269-, I276-, V277-, R293-, S294-, T300N, H301-, Y339-, T340-, K345-, S346-, S347-"}}}]},{"name":"NODE_0000129","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G47746-","A62110-","T62111-","A62112-","A62113-","A62114-","A62116-","T62118-","T62121-","A62122-","T62123-","A62124-","T62125-","A62126-","T62127-","T62128-","T62129-","A62131-","A62132-","A62133-","A62134-","T62135-","T62138-","T62139-","A62140-","T62144-","T62145-","A62148-","T62149-","T62150-","A62151-","A62167-","T62168-","T62169-","T62171-","A62173-","A62174-","T62175-","A62176-","T62177-","A62178-","T62179-","A62181-","T62182-","T62183-","A62184-","A62187-","T62188-","T62189-","T62190-","A62191-","A62192-","T62194-","T62197-","T62198-","A62200-","T62202-","A62203-","T62204-","A62206-","T62207-","T62213-","A62217-","A62219-","A62220-","A62221-","T62222-","T62223-","A62224-","A62227-","T62228-","A62230-","A62231-","A62232-","A62233-","A62236-","T62237-","T62238-","A62239-","A62240-","T62241-","A62242-","A62244-","T62246-","T62247-","A62248-","T62249-","A62252-","A62254-","T62255-","A62259-","T62261-","T62262-","A62263-","A62265-","A62266-","T62270-","T62271-","A62272-","T62273-","A62274-","A62277-","T62278-","A62281-","A62284-","T62285-","T62286-","T62287-","A62288-","T62289-","A62290-","T62291-","T62293-","A62294-","A62295-","A62296-","A62297-","A62298-","T62299-","T62300-","A62301-","A62303-","T62304-","A62306-","A62307-","A62308-","A62310-","A62311-","T62312-","A62313-","T62314-","T62316-","A62318-","A62320-","A62321-","T62324-","T62327-","A62328-","T62330-","T62331-","T62333-","A62334-","T62335-","A62336-","T62338-","A62340-","A62342-","A62343-","T62344-","T62345-","A62347-","A62350-","A62351-","A62352-","A62354-","A62355-","T62356-","T62358-","T62359-","T62360-","T62362-","T62363-","A62364-","A62366-","T62367-","A62368-","T62369-","T62370-","T62371-","T62372-","T62373-","T62374-","T62375-","T62377-","T62378-","A62379-","T62380-","T62381-","A62382-","T62384-","A62385-","A62386-","A62390-","T62392-","T62393-","A62394-","A62395-","T62396-","A62397-","T62399-","A62400-","A62403-","A62404-","T62406-","A62409-","A62410-","A62411-","A62412-","T62414-","A62415-","A62417-","T62419-","T62420-","A62422-","T62423-","T62424-","A62425-","T62426-","T62427-","T62429-","A62430-","T62431-","A62432-","A62433-","T62435-","A62436-","T62437-","A62438-","A62440-","T62441-","A62442-","T62446-","T62447-","A62450-","A62451-","A62452-","T62453-","A62454-","A62455-","T62456-","T62458-","T62459-","T62461-","T62463-","T62464-","T62465-","A62467-","T62468-","A62469-","A62470-","A62471-","A62472-","T62474-","T62475-","A62478-","A62480-","A62481-","A62482-","A62483-","T62484-","T62486-","A62487-","A62489-","A62490-","T62491-","T62492-","T62493-","T62494-","T62495-","T62496-","A62497-","A62498-","A62499-","A62500-","A62501-","T62503-","T62504-","A62505-","T62506-","T62508-","T62509-","T62510-","T62511-","T62514-","A62515-","T62516-","T62517-","A62518-","T62520-","A62521-","A62522-","T62523-","A62524-","T62525-","T62528-","T62531-","T62532-","A62533-","A62535-","T62539-","T62540-","A62541-","T62542-","T62543-","A62544-","T62545-","T62546-","A62547-","A62548-","T62549-","A62550-","T62551-","A62553-","T62555-","A62557-","T62558-","A62560-","A62561-","A62562-","T62563-","A62566-","A62568-","T62573-","T62574-","T62576-","A62577-","A62579-","T62580-","A62581-","T62582-","T62586-","T62587-","T62588-","T62589-","A62590-","T62591-","T62592-","T62593-","A62596-","A62598-","T62599-","T62600-","A62601-","A62603-","T62604-","T62607-","A62608-","A62609-","A62610-","T62611-","A62614-","A62615-","T62616-","A62617-","T62619-","A62621-","A62622-","A62623-","T62625-","A62626-","T62627-","T62629-","T62630-","A62703-","T62704-","A62705-","A62706-","A62707-","A62709-","A62710-","T62711-","T62712-","T62713-","A62715-","A62717-","A62718-","A62719-","T62720-","A62723-","T62724-","T62726-","T62727-","A62728-","A62729-","T62730-","T62732-","A62733-","T62734-","T62735-","A62736-","T62738-","A62739-","A62742-","A62743-","A62744-","T62745-","T62746-","T62747-","T62748-","T62749-","T62750-","A62752-","T62756-","A62757-","T62759-","A62762-","A62763-","T62764-","T62765-","A62767-","A62768-","A62770-","T62771-","T62772-","T62774-","A62775-","A62776-","T62777-","A62780-","T62781-","A62783-","T62784-","T62786-","T62787-","T62789-","A62790-","T62793-","A62794-","T62795-","T62796-","T62797-","A62799-","T62800-","A62804-","T62805-","A62806-","A62807-","A62809-","T62810-","T62812-","T62813-","A62814-","A62815-","T62816-","T62817-","T62818-","A62821-","A62822-","T62823-","A62824-","A62827-","A62828-","T62832-","T62833-","T62834-","T62835-","A62836-","A62837-","T62838-","A62839-","T62840-","T62841-","T62842-","A62845-","T62846-","A62848-","T62849-","A62850-","T62851-","A62852-","T62856-","A62857-","T62859-","T62861-","C62862-","T62863-","T62865-","T62866-","T62867-","A62871-","T62873-","T62874-","A62875-","T62876-","A62877-","T62878-","A62879-","T62882-","T62883-","A62884-","T62885-","T62886-","A62889-","A62891-","A62892-","T62893-","A62894-","A62897-","T62899-","A62901-","T62902-","T62903-","A62904-","T62905-","A62906-","T62907-","A62908-","T62910-","A62913-","A62914-","A62915-","A62916-","A62917-","A62918-","A62920-","A62921-","A62922-","A62923-","T62924-","A62925-","A62926-","T62928-","A62929-","T62931-","A62932-","T62933-","A62934-","A62935-","A62936-","A62937-","T62938-","T62940-","T62942-","A62943-","T62944-","A62947-","A62948-","T62949-","A62953-","A62954-","A62955-","A62956-","A62957-","A62960-","A62961-","A62962-","T62963-","T62964-","A62965-","T62966-","A62969-","T62970-","A62971-","T62972-","A62973-","T62976-","A62977-","T62978-","A62979-","A62981-","A62982-","T62983-","A62988-","A62989-","A62991-","T62992-","T62993-","A62995-","A62996-","T62999-","A63000-","T63001-","T63002-","A63003-","A63004-","T63005-","A63006-","T63008-","T63009-","A63010-","A63011-","T63012-","T63013-","T63015-","T63016-","T63017-","T63018-","T63019-","A63021-","T63023-","T63026-","A63027-","A63028-","A63030-","A63031-","A63035-","T63036-","A63037-","T63040-","T63041-","A63042-","T63043-","T63044-","A63046-","A63048-","T63049-","T63050-","T63052-","A63053-","T63054-","T63057-","T63058-","T63059-","T63060-","A63061-","A63062-","A63063-","T63064-","A63065-","T63066-","T63067-","T63069-","A63070-","T63071-","A63072-","A63073-","T63075-","T63076-","A63078-","A63080-","T63082-","T63083-","A63085-","T63086-","A63087-","A63089-","T63090-","A63091-","T63092-","T63093-","A63094-","A63095-","T63096-","A63098-","A63101-","A63102-","T63103-","T63104-","A63106-","A63107-","A63108-","A63109-","T63110-","T63111-","A63112-","T63113-","T63114-","T63115-","T63116-","T63117-","A63118-","T63119-","A63121-","A63124-","T63127-","T63129-","T63131-","T63132-","T63133-","A63135-","A63138-","T63139-","A63141-","T63142-","T63145-","A63148-","A63153-","T63155-","T63156-","A63157-","A63158-","A63161-","A63162-","A63166-","A63167-","T63168-","A63171-","T63173-","A63174-","A63175-","A63176-","A63177-","T63178-","A63179-","A63180-","A63181-","T63182-","A63183-","T63184-","A63186-","T63187-","T63188-","A63189-","A63190-","T63191-","A63192-","T63193-","A63194-","T63195-","T63198-","T63200-","A63201-","A63203-","T63204-","A63205-","T63206-","T63207-","A63208-","T63210-","A63211-","T63212-","T63213-","T63214-","T63215-","T63216-","A63217-","T63218-","T63219-","A63220-","A63221-","T63222-","T63225-","T63226-","T63227-","A63229-","T63230-","T63231-","A63232-","T63233-","A63235-","T63236-","T63238-","T63239-","T63241-","T63244-","A63245-","A63250-","A63251-","T63252-","A63254-","T63255-","T63256-","A63259-","T63260-","A63262-","T63263-","A63265-","A63266-","A63268-","T63270-","A63272-","T63273-","T63274-","T63275-","A63277-","A63279-","A63280-","A63282-","T63283-","T63286-","A63291-","T63293-","A63294-","T63295-","T63296-","A63297-","A63298-","T63299-","T63303-","T63304-","T63305-","A63306-","T63308-","A63309-","A63310-","A63311-","A63313-","T63315-","A63318-","T63319-","T63322-","T63323-","A63326-","A63327-","T63328-","A63329-","A63330-","T63331-","A63332-","A63333-","A63334-","A63335-","T63337-","T63338-","T63340-","A63343-","A63344-","T63346-","T63347-","A63348-","A63349-","A63350-","A63353-","T63354-","A63355-","T63356-","T63357-","A63358-","T63359-","A63362-","T63363-","T63364-","T63367-","T63368-","T63369-","A63370-","A63371-","A63372-","A63374-","T63375-","A63376-","T63377-","A63379-","T63382-","A63384-","T63385-","T63387-","A63388-","A63389-","A63393-","A63395-","A63397-","A63398-","T63399-","T63400-","T63401-","T63402-","T63403-","T63404-","T63407-","A63408-","T63411-","T63412-","T63413-","T63414-","A63415-","A63417-","A63419-","T63421-","T63422-","T63423-","A63425-","A63426-","T63429-","A63430-","T63432-","T63433-","T63435-","T63436-","T63437-","A63438-","A63439-","A63441-","A63442-","A63443-","T63445-","T63446-","A63447-","T63448-","T63449-","A63451-","T63452-","T63455-","T63458-","T63460-","A63461-","T63463-","A63464-","T63465-","T63466-","T63468-","A63469-","T63470-","T63471-","T63472-","A63473-","A63474-","T63475-","T63476-","T63477-","T63478-","T63480-","A63481-","T63483-","T63484-","A63485-","A63486-","T63487-","T63488-","T63489-","A63490-","T63491-","A63493-","A63495-","T63496-","A63497-","T63498-","A63500-","A63502-","T63503-","T63504-","C89166T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"]}},"children":[{"name":"OQ672570","node_attrs":{"div":2,"accession":"OQ672570","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"02112022_anal"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672570/2022-11-02"},"date":{"value":"2022-11-02"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G49680-","G49710-","G62109-","G62115-","G62117-","C62119-","C62120-","G62130-","C62136-","G62137-","C62141-","G62142-","G62143-","C62146-","G62147-","C62166-","G62170-","G62172-","C62180-","G62185-","G62186-","C62193-","C62195-","C62196-","G62199-","C62201-","C62205-","G62208-","G62209-","C62210-","G62211-","G62212-","G62214-","C62215-","C62216-","G62218-","C62225-","C62226-","C62229-","G62234-","C62235-","C62243-","G62245-","G62250-","C62251-","G62253-","C62256-","G62257-","C62258-","G62260-","G62264-","C62267-","G62268-","G62269-","G62275-","C62276-","C62279-","C62280-","C62282-","C62283-","C62292-","G62302-","C62305-","G62309-","G62315-","G62317-","C62319-","C62322-","G62323-","C62325-","C62326-","G62329-","G62332-","C62337-","G62339-","G62341-","G62346-","C62348-","G62349-","C62353-","G62357-","C62361-","C62365-","C62376-","G62383-","C62387-","C62388-","G62389-","C62391-","G62398-","G62401-","G62402-","C62405-","G62407-","G62408-","C62413-","G62416-","C62418-","G62421-","C62428-","G62434-","G62439-","C62443-","C62444-","C62445-","C62448-","C62449-","G62457-","C62460-","C62462-","G62466-","G62473-","C62476-","C62477-","G62479-","G62485-","G62488-","G62502-","C62507-","G62512-","C62513-","C62519-","C62526-","G62527-","G62529-","G62530-","G62534-","C62536-","G62537-","C62538-","G62552-","G62554-","G62556-","G62559-","C62564-","C62565-","C62567-","C62569-","C62570-","G62571-","C62572-","C62575-","G62578-","C62583-","G62584-","C62585-","C62594-","C62595-","C62597-","G62602-","G62605-","G62606-","C62612-","C62613-","G62618-","G62620-","C62624-","C62628-","C62708-","C62714-","C62716-","G62721-","G62722-","G62725-","G62731-","G62737-","G62740-","G62741-","G62751-","C62753-","G62754-","C62755-","G62758-","G62760-","G62761-","G62766-","G62769-","C62773-","G62778-","G62779-","G62782-","G62785-","C62788-","C62791-","C62792-","C62798-","C62801-","C62802-","G62803-","C62808-","G62811-","C62819-","C62820-","C62825-","C62826-","C62829-","G62830-","G62831-","C62843-","G62844-","G62847-","C62853-","G62854-","G62855-","G62858-","C62860-","C62864-","C62868-","G62869-","G62870-","C62872-","G62880-","C62881-","C62887-","C62888-","C62890-","C62895-","G62896-","G62898-","C62900-","C62909-","C62911-","C62912-","C62919-","C62927-","G62930-","C62939-","G62941-","C62945-","G62946-","G62950-","G62951-","G62952-","C62958-","G62959-","C62967-","G62968-","G62974-","G62975-","G62980-","C62984-","C62985-","G62986-","G62987-","C62990-","G62994-","C62997-","G62998-","C63007-","C63014-","C63020-","G63022-","G63024-","G63025-","G63029-","C63032-","C63033-","G63034-","G63038-","G63039-","G63045-","C63047-","G63051-","G63055-","G63056-","C63068-","C63074-","G63077-","G63079-","C63081-","G63084-","G63088-","G63097-","C63099-","G63100-","G63105-","C63120-","C63122-","C63123-","C63125-","G63126-","G63128-","G63130-","C63134-","G63136-","G63137-","C63140-","C63143-","G63144-","C63146-","G63147-","C63149-","G63150-","C63151-","C63152-","G63154-","C63159-","C63160-","C63163-","C63164-","G63165-","G63169-","G63170-","G63172-","C63185-","G63196-","C63197-","C63199-","G63202-","G63209-","C63223-","C63224-","G63228-","C63234-","C63237-","C63240-","C63242-","G63243-","C63246-","G63247-","C63248-","G63249-","G63253-","C63257-","C63258-","G63261-","C63264-","G63267-","G63269-","G63271-","G63276-","G63278-","C63281-","C63284-","C63285-","C63287-","C63288-","G63289-","G63290-","G63292-","G63300-","G63301-","G63302-","G63307-","C63312-","G63314-","C63316-","C63317-","C63320-","G63321-","G63324-","C63325-","G63336-","G63339-","C63341-","C63342-","G63345-","G63351-","G63352-","G63360-","C63361-","C63365-","G63366-","G63373-","C63378-","C63380-","C63381-","C63383-","C63386-","C63390-","G63391-","G63392-","G63394-","C63396-","G63405-","G63406-","G63409-","G63410-","G63416-","G63418-","C63420-","G63424-","G63427-","C63428-","C63431-","G63434-","C63440-","G63444-","C63450-","C63453-","G63454-","C63456-","G63457-","C63459-","C63462-","C63467-","G63479-","G63482-","C63492-","C63494-","C63499-","C63501-","-180517A","-180518A","-180519T","-180520G","-180521A","-180522C","-180523G","-180524A","-180525T","-180526A","-180527T","-180528A","-180529C","-180530G","-180531G","-180532A","-180533T","-180534T"],"OPG068":["D494-"],"OPG081":["N46-","R47-","T48-","V49-","T50-","I51-","F52-","K53-","Y54-","I55-","G56-","L57-","F58-","I59-"]},"labels":{"aa":"OPG068: D494-; OPG081: N46-, R47-, T48-, V49-, T50-, I51-, F52-, K53-, Y54-, I55-, G56-, L57-, F58-, I59-"}}},{"name":"NODE_0000130","node_attrs":{"div":6,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C2621-","A2623-","C2624-","A2625-","T2626-","A2627-","G2628-","A2629-","T2630-","T2631-","A2632-","C2633-","G2634-","G2635-","C2636-","T2637-","T2638-","C2639-","T2640-","G2641-","T2642-","A2643-","T2644-","T2645-","C2646-","G2647-","T2648-","T2649-","G2650-","T2651-","C2652-","C8201T","-62110A","-62111T","-62112A","-62113A","-62114A","-62116A","-62118T","-62121T","-62122A","-62123T","-62124A","-62125T","-62126A","-62127T","-62128T","-62129T","-62131A","-62132A","-62133A","-62134A","-62135T","-62138T","-62139T","-62140A","-62144T","-62145T","-62148A","-62149T","-62150T","-62151A","-62167A","-62168T","-62169T","-62171T","-62173A","-62174A","-62175T","-62176A","-62177T","-62178A","-62179T","-62181A","-62182T","-62183T","-62184A","-62187A","-62188T","-62189T","-62190T","-62191A","-62192A","-62194T","-62197T","-62198T","-62200A","-62202T","-62203A","-62204T","-62206A","-62207T","-62213T","-62217A","-62219A","-62220A","-62221A","-62222T","-62223T","-62224A","-62227A","-62228T","-62230A","-62231A","-62232A","-62233A","-62236A","-62237T","-62238T","-62239A","-62240A","-62241T","-62242A","-62244A","-62246T","-62247T","-62248A","-62249T","-62252A","-62254A","-62255T","-62259A","-62261T","-62262T","-62263A","-62265A","-62266A","-62270T","-62271T","-62272A","-62273T","-62274A","-62277A","-62278T","-62281A","-62284A","-62285T","-62286T","-62287T","-62288A","-62289T","-62290A","-62291T","-62293T","-62294A","-62295A","-62296A","-62297A","-62298A","-62299T","-62300T","-62301A","-62303A","-62304T","-62306A","-62307A","-62308A","-62310A","-62311A","-62312T","-62313A","-62314T","-62316T","-62318A","-62320A","-62321A","-62324T","-62327T","-62328A","-62330T","-62331T","-62333T","-62334A","-62335T","-62336A","-62338T","-62340A","-62342A","-62343A","-62344T","-62345T","-62347A","-62350A","-62351A","-62352A","-62354A","-62355A","-62356T","-62358T","-62359T","-62360T","-62362T","-62363T","-62364A","-62366A","-62367T","-62368A","-62369T","-62370T","-62371T","-62372T","-62373T","-62374T","-62375T","-62377T","-62378T","-62379A","-62380T","-62381T","-62382A","-62384T","-62385A","-62386A","-62390A","-62392T","-62393T","-62394A","-62395A","-62396T","-62397A","-62399T","-62400A","-62403A","-62404A","-62406T","-62409A","-62410A","-62411A","-62412A","-62414T","-62415A","-62417A","-62419T","-62420T","-62422A","-62423T","-62424T","-62425A","-62426T","-62427T","-62429T","-62430A","-62431T","-62432A","-62433A","-62435T","-62436A","-62437T","-62438A","-62440A","-62441T","-62442A","-62446T","-62447T","-62450A","-62451A","-62452A","-62453T","-62454A","-62455A","-62456T","-62458T","-62459T","-62461T","-62463T","-62464T","-62465T","-62467A","-62468T","-62469A","-62470A","-62471A","-62472A","-62474T","-62475T","-62478A","-62480A","-62481A","-62482A","-62483A","-62484T","-62486T","-62487A","-62489A","-62490A","-62491T","-62492T","-62493T","-62494T","-62495T","-62496T","-62497A","-62498A","-62499A","-62500A","-62501A","-62503T","-62504T","-62505A","-62506T","-62508T","-62509T","-62510T","-62511T","-62514T","-62515A","-62516T","-62517T","-62518A","-62520T","-62521A","-62522A","-62523T","-62524A","-62525T","-62528T","-62531T","-62532T","-62533A","-62535A","-62539T","-62540T","-62541A","-62542T","-62543T","-62544A","-62545T","-62546T","-62547A","-62548A","-62549T","-62550A","-62551T","-62553A","-62555T","-62557A","-62558T","-62560A","-62561A","-62562A","-62563T","-62566A","-62568A","-62573T","-62574T","-62576T","-62577A","-62579A","-62580T","-62581A","-62582T","-62586T","-62587T","-62588T","-62589T","-62590A","-62591T","-62592T","-62593T","-62596A","-62598A","-62599T","-62600T","-62601A","-62603A","-62604T","-62607T","-62608A","-62609A","-62610A","-62611T","-62614A","-62615A","-62616T","-62617A","-62619T","-62621A","-62622A","-62623A","-62625T","-62626A","-62627T","-62629T","-62630T","-62703A","-62704T","-62705A","-62706A","-62707A","-62709A","-62710A","-62711T","-62712T","-62713T","-62715A","-62717A","-62718A","-62719A","-62720T","-62723A","-62724T","-62726T","-62727T","-62728A","-62729A","-62730T","-62732T","-62733A","-62734T","-62735T","-62736A","-62738T","-62739A","-62742A","-62743A","-62744A","-62745T","-62746T","-62747T","-62748T","-62749T","-62750T","-62752A","-62756T","-62757A","-62759T","-62762A","-62763A","-62764T","-62765T","-62767A","-62768A","-62770A","-62771T","-62772T","-62774T","-62775A","-62776A","-62777T","-62780A","-62781T","-62783A","-62784T","-62786T","-62787T","-62789T","-62790A","-62793T","-62794A","-62795T","-62796T","-62797T","-62799A","-62800T","-62804A","-62805T","-62806A","-62807A","-62809A","-62810T","-62812T","-62813T","-62814A","-62815A","-62816T","-62817T","-62818T","-62821A","-62822A","-62823T","-62824A","-62827A","-62828A","-62832T","-62833T","-62834T","-62835T","-62836A","-62837A","-62838T","-62839A","-62840T","-62841T","-62842T","-62845A","-62846T","-62848A","-62849T","-62850A","-62851T","-62852A","-62856T","-62857A","-62859T","-62863T","-62865T","-62866T","-62867T","-62871A","-62873T","-62874T","-62875A","-62876T","-62877A","-62878T","-62879A","-62882T","-62883T","-62884A","-62885T","-62886T","-62889A","-62891A","-62892A","-62893T","-62894A","-62897A","-62899T","-62901A","-62902T","-62903T","-62904A","-62905T","-62906A","-62907T","-62908A","-62910T","-62913A","-62914A","-62915A","-62916A","-62917A","-62918A","-62920A","-62921A","-62922A","-62923A","-62924T","-62925A","-62926A","-62928T","-62929A","-62931T","-62932A","-62933T","-62934A","-62935A","-62936A","-62937A","-62938T","-62940T","-62942T","-62943A","-62944T","-62947A","-62948A","-62949T","-62953A","-62954A","-62955A","-62956A","-62957A","-62960A","-62961A","-62962A","-62963T","-62964T","-62965A","-62966T","-62969A","-62970T","-62971A","-62972T","-62973A","-62976T","-62977A","-62978T","-62979A","-62981A","-62982A","-62983T","-62988A","-62989A","-62991A","-62992T","-62993T","-62995A","-62996A","-62999T","-63000A","-63001T","-63002T","-63003A","-63004A","-63005T","-63006A","-63008T","-63009T","-63010A","-63011A","-63012T","-63013T","-63015T","-63016T","-63017T","-63018T","-63019T","-63021A","-63023T","-63026T","-63027A","-63028A","-63030A","-63031A","-63035A","-63036T","-63037A","-63040T","-63041T","-63042A","-63043T","-63044T","-63046A","-63048A","-63049T","-63050T","-63052T","-63053A","-63054T","-63057T","-63058T","-63059T","-63060T","-63061A","-63062A","-63063A","-63064T","-63065A","-63066T","-63067T","-63069T","-63070A","-63071T","-63072A","-63073A","-63075T","-63076T","-63078A","-63080A","-63082T","-63083T","-63085A","-63086T","-63087A","-63089A","-63090T","-63091A","-63092T","-63093T","-63094A","-63095A","-63096T","-63098A","-63101A","-63102A","-63103T","-63104T","-63106A","-63107A","-63108A","-63109A","-63110T","-63111T","-63112A","-63113T","-63114T","-63115T","-63116T","-63117T","-63118A","-63119T","-63121A","-63124A","-63127T","-63129T","-63131T","-63132T","-63133T","-63135A","-63138A","-63139T","-63141A","-63142T","-63145T","-63148A","-63153A","-63155T","-63156T","-63157A","-63158A","-63161A","-63162A","-63166A","-63167A","-63168T","-63171A","-63173T","-63174A","-63175A","-63176A","-63177A","-63178T","-63179A","-63180A","-63181A","-63182T","-63183A","-63184T","-63186A","-63187T","-63188T","-63189A","-63190A","-63191T","-63192A","-63193T","-63194A","-63195T","-63198T","-63200T","-63201A","-63203A","-63204T","-63205A","-63206T","-63207T","-63208A","-63210T","-63211A","-63212T","-63213T","-63214T","-63215T","-63216T","-63217A","-63218T","-63219T","-63220A","-63221A","-63222T","-63225T","-63226T","-63227T","-63229A","-63230T","-63231T","-63232A","-63233T","-63235A","-63236T","-63238T","-63239T","-63241T","-63244T","-63245A","-63250A","-63251A","-63252T","-63254A","-63255T","-63256T","-63259A","-63260T","-63262A","-63263T","-63265A","-63266A","-63268A","-63270T","-63272A","-63273T","-63274T","-63275T","-63277A","-63279A","-63280A","-63282A","-63283T","-63286T","-63291A","-63293T","-63294A","-63295T","-63296T","-63297A","-63298A","-63299T","-63303T","-63304T","-63305T","-63306A","-63308T","-63309A","-63310A","-63311A","-63313A","-63315T","-63318A","-63319T","-63322T","-63323T","-63326A","-63327A","-63328T","-63329A","-63330A","-63331T","-63332A","-63333A","-63334A","-63335A","-63337T","-63338T","-63340T","-63343A","-63344A","-63346T","-63347T","-63348A","-63349A","-63350A","-63353A","-63354T","-63355A","-63356T","-63357T","-63358A","-63359T","-63362A","-63363T","-63364T","-63367T","-63368T","-63369T","-63370A","-63371A","-63372A","-63374A","-63375T","-63376A","-63377T","-63379A","-63382T","-63384A","-63385T","-63387T","-63388A","-63389A","-63393A","-63395A","-63397A","-63398A","-63399T","-63400T","-63401T","-63402T","-63403T","-63404T","-63407T","-63408A","-63411T","-63412T","-63413T","-63414T","-63415A","-63417A","-63419A","-63421T","-63422T","-63423T","-63425A","-63426A","-63429T","-63430A","-63432T","-63433T","-63435T","-63436T","-63437T","-63438A","-63439A","-63441A","-63442A","-63443A","-63445T","-63446T","-63447A","-63448T","-63449T","-63451A","-63452T","-63455T","-63458T","-63460T","-63461A","-63463T","-63464A","-63465T","-63466T","-63468T","-63469A","-63470T","-63471T","-63472T","-63473A","-63474A","-63475T","-63476T","-63477T","-63478T","-63480T","-63481A","-63483T","-63484T","-63485A","-63486A","-63487T","-63488T","-63489T","-63490A","-63491T","-63493A","-63495A","-63496T","-63497A","-63498T","-63500A","-63502A","-63503T","-63504T","C151552T","C167451T","G187391A","A194549-","A194550-","G194551-","T194552-","G194553-","T194554-","A194555-","A194556-","A194557-","G194558-","A194559-","C194560-","A194561-","A194562-","C194563-","G194564-","A194565-","A194566-","T194567-","A194568-","C194569-","A194570-","G194571-","A194572-","A194573-","G194574-","C194575-","C194576-","G194577-","T194578-","A194579-","A194580-","T194581-","C194582-","T194583-","A194584-","T194585-"],"OPG002":["R38-","S39-","R40-","N41-","L42-","C43-","C44-","L45-","S46-","C47-"],"OPG002_dup":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-","R38-","S39-","R40-","N41-","L42-","C43-"],"OPG178":["S15F"]},"labels":{"aa":"OPG002: R38-, S39-, R40-, N41-, L42-, C43-, C44-, L45-, S46-, C47-; OPG002_dup: K31-, C32-, K33-, D34-, N35-, E36-, Y37-, R38-, S39-, R40-, N41-, L42-, C43-; OPG178: S15F"}},"children":[{"name":"OQ672572","node_attrs":{"div":6,"accession":"OQ672572","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"26012023_anal"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672572/2023-01-26"},"date":{"value":"2023-01-26"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-47746G","-62861T","-62862C"]}}},{"name":"OQ672574","node_attrs":{"div":6,"accession":"OQ672574","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"02022023_anal"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672574/2023-02-02"},"date":{"value":"2023-02-02"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-2623A","-2624C","-2625A","-2626T","-2627A","-2628G","-2629A","-2630T","-2631T","-2632A","-2633C","-2634G","-2635G","-2636C","-2637T","-2638T","-2639C","-2640T","-2641G","-2642T","-2643A","-2644T","-2645T","-2646C","-2647G","-2648T","-2649T","-2650G","-2651T","-2652C","-194549A","-194550A","-194551G","-194552T","-194553G","-194554T","-194555A","-194556A","-194557A","-194558G","-194559A","-194560C","-194561A","-194562A","-194563C","-194564G","-194565A","-194566A","-194567T","-194568A","-194569C","-194570A","-194571G","-194572A","-194573A","-194574G","-194575C","-194576C","-194577G","-194578T","-194579A","-194580A","-194581T","-194582C","-194583T","-194584A","-194585T"],"OPG002":["-38R","-39S","-40R","-41N","-42L","-43C","-45L","-46S","-47C"],"OPG002_dup":["-31K","-32C","-33K","-34D","-35N","-36E","-37Y","-38R","-39S","-40R","-41N","-42L","-43C"]},"labels":{"aa":"OPG002: -38R, -39S, -40R, -41N, -42L, -43C, -45L, -46S, -47C; OPG002_dup: -31K, -32C, -33K, -34D, -35N, -36E, -37Y, -38R, -39S, -40R, -41N, -42L, -43C"}}},{"name":"NODE_0000131","node_attrs":{"div":7,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A2611-","C2612-","A2613-","C2614-","G2615-","A2616-","T2617-","A2618-","G2619-","A2620-","A2622-","T2653-","T2654-","T2655-","A2656-","C2657-","A2658-","C2659-","T2660-","T2661-","T39397C","T47695-","C47696-","A47697-","T47698-","T47699-","A47700-","C47701-","G47702-","A47703-","G47704-","A47705-","C47706-","A47707-","T47708-","T47709-","G47710-","A47711-","A47712-","A47713-","C47714-","T47715-","A47716-","G47717-","G47718-","A47719-","T47720-","A47721-","T47722-","A47723-","T47724-","A47725-","A47726-","A47727-","A47728-","T47729-","T47730-","T47731-","A47732-","A47733-","G47734-","G47735-","G47736-","A47737-","A47738-","T47739-","G47740-","A47741-","T47742-","T47743-","A47744-","G47745-","A47747-","C47748-","T47749-","A47750-","C47751-","T47752-","A47753-","C47754-","T47755-","C47756-","T47757-","A47758-","G47759-","A47760-","A47761-","G47762-","A47763-","T47764-","A47765-","T47766-","A47767-","G47768-","C47769-","A47770-","C47771-","C47772-","A47773-","T47774-","C47775-","T47776-","A47777-","T47778-","T47779-","C47780-","C47781-","A47782-","A47783-","A47784-","T47785-","A47786-","A47787-","T47788-","C47789-","A47790-","G47791-","A47792-","A47793-","A47794-","A47795-","C47796-","T47797-","T47798-","A47799-","T47800-","A47801-","A47802-","A47803-","C47804-","T47805-","A47806-","T47807-","T47808-","C47809-","T47810-","C47811-","G47812-","G47813-","A47814-","C47815-","A47816-","T47817-","T47818-","T47819-","C47820-","A47821-","G47822-","T47823-","C47824-","A47825-","T47826-","T47827-","G47828-","G47829-","C47830-","A47831-","A47832-","A47833-","G47834-","C47835-","A47836-","T47837-","C47838-","A47839-","C47840-","A47841-","G47842-","A47843-","A47844-","T47845-","C47846-","C47847-","G47848-","A47849-","G47850-","T47851-","A47852-","A47853-","G47854-","A47855-","T47856-","G47857-","A47858-","T47859-","A47860-","T47861-","A47862-","T47863-","G47864-","C47865-","T47866-","C47867-","G47868-","C47869-","T47870-","G47871-","C47872-","T47873-","T47874-","T47875-","A47876-","C47877-","A47878-","T47879-","G47880-","T47881-","T47882-","T47883-","C47884-","C47885-","C47886-","A47887-","A47888-","T47889-","T47890-","T47891-","G47892-","T47893-","T47894-","T47895-","G47896-","G47897-","A47898-","G47899-","A47900-","T47901-","G47902-","A47903-","C47904-","C47905-","A47906-","T47907-","A47908-","G47909-","A47910-","T47911-","T47912-","C47913-","A47914-","T47915-","T47916-","T47917-","G47918-","T47919-","T47920-","A47921-","T47922-","A47923-","G47924-","A47925-","A47926-","T47927-","G47928-","C47929-","A47930-","T47931-","C47932-","C47933-","A47934-","A47935-","C47936-","A47937-","T47938-","T47939-","G47940-","T47941-","T47942-","C47943-","A47944-","T47945-","G47946-","A47947-","T47948-","A47949-","T47950-","A47951-","G47952-","T47953-","T47954-","G47955-","A47956-","A47957-","T47958-","C47959-","A47960-","T47961-","G47962-","T47963-","A47964-","T47965-","G47966-","C47967-","C47968-","T47969-","G47970-","T47971-","T47972-","C47973-","G47974-","T47975-","A47976-","T47977-","G47978-","C47979-","C47980-","T47981-","G47982-","T47983-","G47984-","G47985-","C47986-","T47987-","A47988-","A47989-","G47990-","A47991-","T47992-","A47993-","C47994-","T47995-","G47996-","T47997-","G47998-","T47999-","A48000-","A48001-","A48002-","G48003-","A48004-","A48005-","A48006-","T48007-","G48008-","G48009-","T48010-","A48011-","A48012-","A48013-","T48014-","A48015-","A48016-","A48017-","T48018-","A48019-","C48020-","T48021-","T48022-","T48023-","G48024-","A48025-","G48026-","A48027-","A48028-","T48029-","C48030-","T48031-","T48032-","T48033-","A48034-","A48035-","G48036-","A48037-","G48038-","T48039-","G48040-","C48041-","A48042-","T48043-","T48044-","G48045-","A48046-","C48047-","T48048-","T48049-","T48050-","G48051-","T48052-","T48053-","A48054-","G48055-","T48056-","G48057-","A48058-","A48059-","T48060-","A48061-","G48062-","G48063-","C48064-","A48065-","T48066-","T48067-","C48068-","C48069-","A48070-","T48071-","C48072-","T48073-","T48074-","T48075-","C48076-","T48077-","C48078-","C48079-","A48080-","A48081-","T48082-","A48083-","C48084-","T48085-","A48086-","A48087-","T48088-","T48089-","C48090-","A48091-","A48092-","A48093-","T48094-","T48095-","G48096-","T48097-","T48098-","A48099-","A48100-","A48101-","T48102-","T48103-","A48104-","A48105-","T48106-","A48107-","A48108-","T48109-","G48110-","G48111-","A48112-","A48113-","T48114-","A48115-","G48116-","T48117-","A48118-","T48119-","A48120-","A48121-","A48122-","T48123-","A48124-","G48125-","T48126-","T48127-","A48128-","T48129-","T48130-","A48131-","G48132-","T48133-","G48134-","A48135-","T48136-","A48137-","G48138-","G48139-","A48140-","T48141-","A48142-","G48143-","T48144-","A48145-","A48146-","A48147-","C48148-","A48149-","T48150-","A48151-","A48152-","T48153-","T48154-","A48155-","T48156-","T48157-","A48158-","G48159-","A48160-","A48161-","T48162-","A48163-","G48164-","T48165-","A48166-","G48167-","T48168-","G48169-","T48170-","A48171-","G48172-","T48173-","A48174-","T48175-","C48176-","A48177-","T48178-","A48179-","G48180-","A48181-","T48182-","A48183-","A48184-","C48185-","T48186-","C48187-","T48188-","C48189-","T48190-","T48191-","C48192-","T48193-","A48194-","T48195-","A48196-","A48197-","A48198-","A48199-","A48200-","A48201-","T48202-","G48203-","G48204-","A48205-","T48206-","T48207-","T48208-","T48209-","A48210-","T48211-","T48212-","C48213-","G48214-","T48215-","A48216-","G48217-","A48218-","A48219-","A48220-","G48221-","T48222-","A48223-","T48224-","C48225-","T48226-","T48227-","A48228-","T48229-","A48230-","T48231-","A48232-","C48233-","A48234-","C48235-","A48236-","G48237-","T48238-","A48239-","G48240-","A48241-","A48242-","A48243-","A48244-","T48245-","A48246-","A48247-","T48248-","A48249-","T48250-","A48251-","G48252-","A48253-","T48254-","T48255-","T48256-","T48257-","T48258-","T48259-","A48260-","A48261-","A48262-","G48263-","G48264-","A48265-","T48266-","G48267-","A48268-","T48269-","A48270-","C48271-","A48272-","T48273-","T48274-","A48275-","A48276-","G48277-","T48278-","A48279-","A48280-","A48281-","G48282-","T48283-","A48284-","A48285-","A48286-","C48287-","A48288-","A48289-","T48290-","T48291-","T48292-","T48293-","A48294-","C48295-","C48296-","C48297-","T48298-","C48299-","A48300-","A48301-","T48302-","C48303-","A48304-","T48305-","G48306-","T48307-","A48308-","C48309-","T48310-","A48311-","G48312-","C48313-","T48314-","C48315-","T48316-","C48317-","A48318-","A48319-","G48320-","T48321-","A48322-","T48323-","C48324-","T48325-","A48326-","G48327-","T48328-","T48329-","A48330-","G48331-","C48332-","A48333-","A48334-","T48335-","T48336-","T48337-","T48338-","C48339-","C48340-","T48341-","C48342-","A48343-","A48344-","C48345-","A48346-","T48347-","G48348-","T48349-","T48350-","A48351-","T48352-","T48353-","A48354-","C48355-","T48356-","A48357-","A48358-","G48359-","G48360-","A48361-","T48362-","G48363-","T48364-","A48365-","T48366-","T48367-","A48368-","G48369-","C48370-","T48371-","A48372-","A48373-","T48374-","A48375-","C48376-","C48377-","A48378-","A48379-","T48380-","T48381-","T48382-","T48383-","T48384-","T48385-","T48386-","G48387-","T48388-","T48389-","T48390-","T48391-","C48392-","A48393-","T48394-","A48395-","C48396-","A48397-","T48398-","A48399-","T48400-","G48401-","G48402-","T48403-","A48404-","C48405-","G48406-","A48407-","T48408-","G48409-","C48410-","T48411-","G48412-","T48413-","A48414-","A48415-","A48416-","G48417-","T48418-","A48419-","T48420-","A48421-","C48422-","G48423-","A48424-","A48425-","G48426-","C48427-","G48428-","G48429-","T48430-","T48431-","T48432-","T48433-","A48434-","C48435-","G48436-","A48437-","C48438-","A48439-","C48440-","G48441-","C48442-","A48443-","T48444-","T48445-","T48446-","G48447-","A48448-","T48449-","G48450-","C48451-","A48452-","C48453-","C48454-","C48455-","A48456-","C48457-","G48458-","T48459-","T48460-","G48461-","T48462-","A48463-","C48464-","G48465-","T48466-","T48467-","A48468-","A48469-","A48470-","G48471-","C48472-","A48473-","T48474-","T48475-","G48476-","A48477-","C48478-","T48479-","A48480-","A48481-","G48482-","A48483-","A48484-","T48485-","T48486-","A48487-","T48488-","T48489-","T48490-","A48491-","T48492-","C48493-","G48494-","T48495-","T48496-","T48497-","A48498-","G48499-","T48500-","A48501-","A48502-","C48503-","A48504-","C48505-","A48506-","A48507-","T48508-","A48509-","C48510-","A48511-","G48512-","T48513-","C48514-","G48515-","T48516-","A48517-","C48518-","A48519-","A48520-","G48521-","G48522-","A48523-","A48524-","A48525-","C48526-","A48527-","G48528-","T48529-","G48530-","C48531-","A48532-","T48533-","A48534-","A48535-","A48536-","C48537-","T48538-","A48539-","A48540-","C48541-","A48542-","C48543-","A48544-","A48545-","G48546-","A48547-","T48548-","G48549-","A48550-","A48551-","A48552-","A48553-","A48554-","T48555-","T48556-","T48557-","T48558-","T48559-","A48560-","G48561-","A48562-","G48563-","G48564-","T48565-","T48566-","G48567-","C48568-","C48569-","G48570-","A48571-","A48572-","T48573-","A48574-","C48575-","A48576-","T48577-","G48578-","G48579-","A48580-","C48581-","G48582-","A48583-","A48584-","T48585-","T48586-","A48587-","G48588-","G48589-","A48590-","G48591-","A48592-","A48593-","C48594-","T48595-","T48596-","A48597-","T48598-","A48599-","G48600-","G48601-","C48602-","G48603-","T48604-","A48605-","A48606-","A48607-","T48608-","T48609-","A48610-","T48611-","G48612-","A48613-","C48614-","T48615-","T48616-","A48617-","G48618-","T48619-","T48620-","C48621-","T48622-","T48623-","A48624-","A48625-","T48626-","C48627-","C48628-","A48629-","T48630-","T48631-","A48632-","T48633-","T48634-","T48635-","C48636-","A48637-","C48638-","G48639-","G48640-","A48641-","G48642-","G48643-","G48644-","G48645-","A48646-","A48647-","C48648-","C48649-","C48650-","A48651-","T48652-","C48653-","A48654-","A48655-","A48656-","G48657-","A48658-","T48659-","A48660-","T48661-","G48662-","G48663-","A48664-","A48665-","A48666-","T48667-","C48668-","A48669-","T48670-","T48671-","T48672-","T48673-","T48674-","T48675-","T48676-","A48677-","A48678-","A48679-","A48680-","C48681-","T48682-","G48683-","T48684-","T48685-","T48686-","A48687-","A48688-","G48689-","A48690-","A48691-","A48692-","A48693-","C48694-","A48695-","G48696-","A48697-","C48698-","T48699-","T48700-","C48701-","A48702-","A48703-","A48704-","G48705-","T48706-","T48707-","G48708-","T48709-","T48710-","A48711-","A48712-","A48713-","A48714-","A48715-","A48716-","T48717-","T48718-","A48719-","A48720-","G48721-","T48722-","G48723-","T48724-","T48725-","A48726-","T48727-","A48728-","A48729-","G48730-","A48731-","T48732-","T48733-","A48734-","C48735-","T48736-","T48737-","A48738-","T48739-","T48740-","T48741-","G48742-","G48743-","G48744-","C48745-","A48746-","T48747-","A48748-","C48749-","C48750-","T48751-","A48752-","A48753-","G48754-","C48755-","A48756-","A48757-","G48758-","A48759-","A48760-","A48761-","G48762-","A48763-","T48764-","A48765-","C48766-","A48767-","G48768-","G48769-","C48770-","A48771-","T48772-","A48773-","G48774-","A48775-","G48776-","T48777-","T48778-","T48779-","G48780-","C48781-","G48782-","G48783-","A48784-","T48785-","A48786-","A48787-","T48788-","G48789-","A48790-","T48791-","A48792-","G48793-","A48794-","C48795-","A48796-","A48797-","G48798-","A48799-","T48800-","A48801-","T48802-","A48803-","T48804-","A48805-","T48806-","A48807-","C48808-","T48809-","C48810-","T48811-","A48812-","T48813-","T48814-","T48815-","C48816-","A48817-","A48818-","C48819-","A48820-","A48821-","A48822-","C48823-","T48824-","G48825-","G48826-","T48827-","A48828-","G48829-","A48830-","A48831-","T48832-","A48833-","G48834-","T48835-","C48836-","C48837-","A48838-","T48839-","A48840-","G48841-","C48842-","A48843-","A48844-","T48845-","C48846-","T48847-","A48848-","A48849-","C48850-","A48851-","G48852-","A48853-","A48854-","A48855-","C48856-","G48857-","T48858-","T48859-","T48860-","A48861-","G48862-","G48863-","G48864-","A48865-","T48866-","T48867-","A48868-","T48869-","A48870-","T48871-","C48872-","T48873-","T48874-","T48875-","C48876-","C48877-","C48878-","G48879-","G48880-","A48881-","G48882-","A48883-","T48884-","A48885-","A48886-","G48887-","A48888-","C48889-","T48890-","A48891-","G48892-","C48893-","T48894-","A48895-","T48896-","T48897-","G48898-","G48899-","G48900-","T48901-","G48902-","T48903-","G48904-","G48905-","T48906-","T48907-","A48908-","A48909-","A48910-","C48911-","G48912-","A48913-","A48914-","A48915-","G48916-","T48917-","A48918-","T48919-","A48920-","G48921-","C48922-","T48923-","A48924-","A48925-","T48926-","G48927-","A48928-","T48929-","G48930-","C48931-","G48932-","G48933-","A48934-","T48935-","A48936-","T48937-","C48938-","G48939-","T48940-","T48941-","A48942-","T48943-","T48944-","A48945-","A48946-","T48947-","A48948-","G48949-","A48950-","C48951-","C48952-","C48953-","G48954-","C48955-","C48956-","A48957-","T48958-","T48959-","A48960-","C48961-","C48962-","A48963-","T48964-","G48965-","T48966-","A48967-","T48968-","G48969-","A48970-","T48971-","A48972-","A48973-","A48974-","A48975-","T48976-","T48977-","C48978-","T48979-","T48980-","A48981-","G48982-","T48983-","T48984-","A48985-","T48986-","A48987-","T48988-","A48989-","T48990-","A48991-","C48992-","T48993-","C48994-","T48995-","G48996-","A48997-","G48998-","A48999-","T49000-","A49001-","A49002-","A49003-","A49004-","C49005-","A49006-","G49007-","G49008-","G49009-","A49010-","C49011-","G49012-","C49013-","G49014-","T49015-","T49016-","A49017-","A49018-","T49019-","A49020-","A49021-","A49022-","A49023-","A49024-","C49025-","A49026-","T49027-","G49028-","C49029-","T49030-","T49031-","A49032-","A49033-","G49034-","T49035-","T49036-","A49037-","G49038-","T49039-","T49040-","T49041-","A49042-","T49043-","A49044-","T49045-","C49046-","T49047-","T49048-","T49049-","G49050-","A49051-","G49052-","C49053-","C49054-","T49055-","G49056-","A49057-","A49058-","A49059-","A49060-","A49061-","G49062-","A49063-","T49064-","A49065-","T49066-","C49067-","A49068-","G49069-","A49070-","G49071-","A49072-","A49073-","C49074-","T49075-","T49076-","C49077-","T49078-","G49079-","C49080-","T49081-","A49082-","G49083-","A49084-","A49085-","A49086-","T49087-","C49088-","A49089-","T49090-","A49091-","T49092-","A49093-","T49094-","G49095-","A49096-","T49097-","A49098-","T49099-","T49100-","C49101-","C49102-","T49103-","G49104-","G49105-","A49106-","G49107-","A49108-","T49109-","A49110-","T49111-","C49112-","C49113-","T49114-","A49115-","T49116-","C49117-","T49118-","A49119-","T49120-","T49121-","A49122-","T49123-","T49124-","G49125-","A49126-","T49127-","G49128-","C49129-","A49130-","A49131-","A49132-","A49133-","A49134-","A49135-","C49136-","G49137-","A49138-","C49139-","G49140-","A49141-","T49142-","T49143-","G49144-","G49145-","A49146-","A49147-","A49148-","A49149-","A49150-","A49151-","T49152-","A49153-","T49154-","T49155-","T49156-","T49157-","A49158-","T49159-","T49160-","A49161-","G49162-","T49163-","T49164-","T49165-","T49166-","T49167-","A49168-","C49169-","A49170-","A49171-","A49172-","G49173-","C49174-","T49175-","A49176-","A49177-","T49178-","T49179-","T49180-","T49181-","A49182-","T49183-","T49184-","A49185-","A49186-","C49187-","G49188-","G49189-","T49190-","A49191-","A49192-","T49193-","A49194-","C49195-","A49196-","T49197-","T49198-","T49199-","A49200-","T49201-","T49202-","A49203-","G49204-","T49205-","G49206-","A49207-","T49208-","A49209-","G49210-","A49211-","A49212-","C49213-","G49214-","T49215-","T49216-","T49217-","A49218-","A49219-","C49220-","G49221-","A49222-","T49223-","G49224-","A49225-","C49226-","T49227-","T49228-","A49229-","T49230-","T49231-","C49232-","A49233-","G49234-","A49235-","G49236-","T49237-","T49238-","G49239-","T49240-","T49241-","G49242-","T49243-","T49244-","C49245-","A49246-","A49247-","A49248-","T49249-","A49250-","G49251-","A49252-","T49253-","C49254-","C49255-","C49256-","G49257-","A49258-","A49259-","T49260-","A49261-","T49262-","T49263-","T49264-","C49265-","G49266-","A49267-","T49268-","A49269-","A49270-","T49271-","G49272-","A49273-","A49274-","C49275-","G49276-","A49277-","A49278-","T49279-","T49280-","A49281-","T49282-","G49283-","T49284-","C49285-","T49286-","T49287-","T49288-","A49289-","T49290-","T49291-","C49292-","T49293-","A49294-","T49295-","A49296-","C49297-","G49298-","A49299-","G49300-","T49301-","G49302-","C49303-","T49304-","G49305-","C49306-","G49307-","G49308-","A49309-","C49310-","A49311-","T49312-","T49313-","A49314-","A49315-","A49316-","C49317-","G49318-","A49319-","T49320-","T49321-","T49322-","G49323-","A49324-","T49325-","G49326-","A49327-","G49328-","T49329-","T49330-","A49331-","G49332-","A49333-","T49334-","A49335-","T49336-","T49337-","A49338-","A49339-","T49340-","A49341-","A49342-","C49343-","A49344-","G49345-","T49346-","T49347-","A49348-","T49349-","A49350-","T49351-","A49352-","T49353-","C49354-","T49355-","A49356-","A49357-","T49358-","A49359-","T49360-","A49361-","A49362-","T49363-","T49364-","T49365-","A49366-","T49367-","G49368-","A49369-","G49370-","G49371-","T49372-","G49373-","A49374-","A49375-","C49376-","G49377-","A49378-","T49379-","A49380-","T49381-","C49382-","A49383-","C49384-","A49385-","T49386-","T49387-","A49388-","G49389-","A49390-","T49391-","A49392-","C49393-","A49394-","A49395-","T49396-","G49397-","G49398-","A49399-","T49400-","G49401-","A49402-","T49403-","A49404-","T49405-","G49406-","A49407-","A49408-","G49409-","A49410-","A49411-","G49412-","T49413-","G49414-","T49415-","C49416-","A49417-","A49418-","A49419-","T49420-","C49421-","T49422-","T49423-","T49424-","A49425-","A49426-","C49427-","G49428-","A49429-","G49430-","G49431-","A49432-","T49433-","A49434-","C49435-","G49436-","T49437-","T49438-","G49439-","T49440-","A49441-","T49442-","T49443-","A49444-","T49445-","G49446-","T49447-","T49448-","A49449-","A49450-","G49451-","G49452-","A49453-","A49454-","T49455-","A49456-","C49457-","A49458-","A49459-","T49460-","A49461-","C49462-","A49463-","T49464-","A49465-","C49466-","C49467-","T49468-","G49469-","T49470-","T49471-","T49472-","T49473-","T49474-","G49475-","C49476-","A49477-","C49478-","G49479-","A49480-","G49481-","T49482-","C49483-","G49484-","G49485-","A49486-","T49487-","C49488-","C49489-","C49490-","A49491-","T49492-","G49493-","G49494-","T49495-","C49496-","A49497-","T49498-","A49499-","G49500-","A49501-","G49502-","A49503-","A49504-","C49505-","G49506-","G49507-","A49508-","A49509-","T49510-","A49511-","C49512-","T49513-","A49514-","A49515-","A49516-","G49517-","A49518-","A49519-","A49520-","C49521-","T49522-","G49523-","T49524-","C49525-","A49526-","T49527-","C49528-","T49529-","A49530-","T49531-","A49532-","A49533-","A49534-","A49535-","T49536-","C49537-","C49538-","A49539-","A49540-","G49541-","A49542-","G49543-","T49544-","A49545-","G49546-","A49547-","C49548-","G49549-","G49550-","C49551-","T49552-","G49553-","A49554-","A49555-","C49556-","T49557-","T49558-","G49559-","T49560-","T49561-","T49562-","A49563-","G49564-","C49565-","A49566-","A49567-","A49568-","A49569-","A49570-","C49571-","A49572-","T49573-","T49574-","T49575-","T49576-","A49577-","A49578-","A49579-","A49580-","T49581-","A49582-","T49583-","T49584-","A49585-","T49586-","T49587-","T49588-","A49589-","G49590-","A49591-","C49592-","G49593-","G49594-","A49595-","C49596-","A49597-","A49598-","T49599-","T49600-","G49601-","G49602-","C49603-","T49604-","C49605-","G49606-","T49607-","C49608-","T49609-","A49610-","G49611-","G49612-","T49613-","C49614-","T49615-","T49616-","G49617-","T49618-","G49619-","T49620-","T49621-","A49622-","G49623-","A49624-","T49625-","G49626-","A49627-","T49628-","T49629-","A49630-","T49631-","A49632-","A49633-","A49634-","G49635-","G49636-","A49637-","G49638-","A49639-","C49640-","T49641-","T49642-","A49643-","T49644-","T49645-","A49646-","G49647-","T49648-","T49649-","A49650-","A49651-","A49652-","A49653-","T49654-","G49655-","A49656-","T49657-","A49658-","A49659-","A49660-","C49661-","C49662-","A49663-","T49664-","C49665-","T49666-","C49667-","A49668-","A49669-","A49670-","T49671-","C49672-","T49673-","G49674-","T49675-","G49676-","G49677-","A49678-","G49679-","G49680-","A49681-","T49682-","G49683-","T49684-","A49685-","T49686-","C49687-","C49688-","G49689-","C49690-","A49691-","T49692-","T49693-","C49694-","G49695-","T49696-","T49697-","A49698-","G49699-","A49700-","T49701-","T49702-","T49703-","T49704-","C49705-","T49706-","A49707-","C49708-","A49709-","G49710-","A49711-","G61794-","G61795-","C61796-","A61797-","T61798-","A61815-","G61816-","T61817-","A61818-","C61819-","A61820-","A61821-","G61822-","T61823-","G61824-","G61825-","C61826-","T61827-","G61828-","C61829-","T61830-","A61831-","T61832-","T61833-","T61834-","C61835-","G61836-","G61837-","C61838-","T61839-","G61840-","C61841-","C61842-","A61843-","G61844-","A61845-","G61846-","T61847-","G61848-","T61849-","C61850-","C61851-","A61852-","A61853-","T61854-","T61855-","C61856-","T61857-","A61858-","C61859-","C61860-","G61861-","T61862-","T61863-","G61864-","T61865-","T61866-","A61867-","C61868-","T61869-","C61870-","C61871-","A61872-","T61873-","T61874-","A61875-","T61876-","A61877-","T61878-","A61879-","T61880-","T61881-","C61882-","C61883-","T61884-","T61885-","G61886-","A61887-","A61888-","T61889-","A61890-","A61891-","C61892-","C61893-","T61894-","T61895-","C61896-","A61897-","T61898-","A61899-","G61900-","C61901-","T61902-","A61903-","T61904-","T61905-","T61906-","T61907-","A61908-","A61909-","T61910-","A61911-","G61912-","G61913-","A61914-","T61915-","C61916-","T61917-","A61918-","T61919-","A61920-","T61921-","G61922-","A61923-","T61924-","C61925-","A61926-","G61927-","T61928-","G61929-","T61930-","T61931-","T61932-","A61933-","A61934-","G61935-","C61936-","C61937-","A61938-","T61939-","A61940-","G61941-","C61942-","A61943-","C61944-","A61945-","A61946-","T61947-","T61948-","T61949-","T61950-","C61951-","T61952-","A61953-","A61954-","T61955-","A61956-","C61957-","G61958-","A61959-","G61960-","A61961-","C61962-","G61963-","T61964-","G61965-","A61966-","T61967-","T61968-","T61969-","T61970-","A61971-","T61972-","C61973-","A61974-","A61975-","A61976-","C61977-","A61978-","T61979-","G61980-","A61981-","C61982-","A61983-","T61984-","T61985-","T61986-","T61987-","C61988-","C61989-","T61990-","T61991-","G61992-","T61993-","A61994-","T61995-","C61996-","C61997-","A61998-","T61999-","T62000-","T62001-","C62002-","G62003-","T62004-","T62005-","T62006-","A62007-","A62008-","T62009-","G62010-","A62011-","C62012-","A62013-","A62014-","A62015-","C62016-","A62017-","T62018-","T62019-","T62020-","T62021-","T62022-","G62023-","T62024-","T62025-","G62026-","G62027-","T62028-","G62029-","T62030-","A62031-","A62032-","T62033-","A62034-","A62035-","A62036-","A62037-","A62038-","A62039-","A62040-","A62041-","T62042-","T62043-","A62044-","T62045-","T62046-","T62047-","A62048-","A62049-","T62050-","T62051-","T62052-","T62053-","T62054-","C62055-","A62056-","T62057-","T62058-","A62059-","A62060-","T62061-","A62062-","G62063-","G62064-","G62065-","A62066-","T62067-","T62068-","T62069-","G62070-","A62071-","C62072-","G62073-","T62074-","A62075-","T62076-","G62077-","T62078-","A62079-","G62080-","C62081-","G62082-","T62083-","A62084-","C62085-","A62086-","A62087-","A62088-","A62089-","T62090-","T62091-","A62092-","T62093-","C62094-","G62095-","T62096-","T62097-","C62098-","C62099-","T62100-","G62101-","G62102-","T62103-","A62104-","T62105-","A62106-","T62107-","A62108-","G62109-","A62110-","T62111-","A62112-","A62113-","A62114-","G62115-","A62116-","G62117-","T62118-","C62119-","C62120-","T62121-","A62122-","T62123-","A62124-","T62125-","A62126-","T62127-","T62128-","T62129-","G62130-","A62131-","A62132-","A62133-","A62134-","T62135-","C62136-","G62137-","T62138-","T62139-","A62140-","C62141-","G62142-","G62143-","T62144-","T62145-","C62146-","G62147-","A62148-","T62149-","T62150-","A62151-","A62152-","A62153-","C62154-","T62155-","T62156-","T62157-","A62158-","A62159-","T62160-","G62161-","A62162-","T62163-","T62164-","G62165-","C62166-","A62167-","T62168-","T62169-","G62170-","T62171-","G62172-","A62173-","A62174-","T62175-","A62176-","T62177-","A62178-","T62179-","C62180-","A62181-","T62182-","T62183-","A62184-","G62185-","G62186-","A62187-","T62188-","T62189-","T62190-","A62191-","A62192-","C62193-","T62194-","C62195-","C62196-","T62197-","T62198-","G62199-","A62200-","C62201-","T62202-","A62203-","T62204-","C62205-","A62206-","T62207-","G62208-","G62209-","C62210-","G62211-","G62212-","T62213-","G62214-","C62215-","C62216-","A62217-","G62218-","A62219-","A62220-","A62221-","T62222-","T62223-","A62224-","C62225-","C62226-","A62227-","T62228-","C62229-","A62230-","A62231-","A62232-","A62233-","G62234-","C62235-","A62236-","T62237-","T62238-","A62239-","A62240-","T62241-","A62242-","C62243-","A62244-","G62245-","T62246-","T62247-","A62248-","T62249-","G62250-","C62251-","A62252-","G62253-","A62254-","T62255-","C62256-","G62257-","C62258-","A62259-","G62260-","T62261-","T62262-","A62263-","G62264-","A62265-","A62266-","C62267-","G62268-","G62269-","T62270-","T62271-","A62272-","T62273-","A62274-","G62275-","C62276-","A62277-","T62278-","C62279-","C62280-","A62281-","C62282-","C62283-","A62284-","T62285-","T62286-","T62287-","A62288-","T62289-","A62290-","T62291-","C62292-","T62293-","A62294-","A62295-","A62303-","T62304-","C62305-","A62306-","A62307-","A62308-","G62309-","A62310-","A62311-","T62312-","A62313-","T62314-","G62315-","T62316-","G62317-","A62318-","C62319-","A62320-","A62321-","C62322-","G62323-","T62324-","C62325-","C62326-","T62327-","A62328-","G62329-","T62330-","T62331-","G62332-","T62333-","A62334-","T62335-","A62336-","C62337-","T62338-","G62339-","A62340-","G62341-","A62342-","A62343-","T62344-","T62345-","G62346-","A62347-","C62348-","G62349-","A62350-","A62351-","A62352-","C62353-","A62354-","A62355-","T62356-","G62357-","T62373-","T62374-","T62375-","C62376-","T62377-","T62378-","A62379-","T62380-","T62381-","A62382-","G62383-","T62384-","A62385-","A62386-","C62387-","C62388-","G62389-","A62390-","C62391-","T62392-","T62393-","A62394-","A62395-","T62396-","A62397-","G62398-","T62399-","A62400-","G62401-","G62402-","A62403-","A62404-","C62405-","T62406-","G62407-","G62408-","A62409-","A62410-","A62411-","A62412-","C62413-","T62414-","A62415-","G62416-","A62417-","C62418-","T62419-","T62420-","G62421-","A62422-","T62423-","T62424-","A62425-","T62426-","T62427-","C62428-","T62429-","A62430-","T62431-","A62432-","A62433-","G62434-","T62435-","A62436-","T62437-","A62438-","G62439-","A62440-","T62441-","A62442-","C62443-","C62444-","C62445-","T62446-","T62447-","C62448-","C62449-","A62450-","A62451-","A62452-","T62453-","A62454-","A62455-","T62456-","G62457-","T62458-","T62459-","C62460-","T62461-","C62462-","T62463-","T62464-","T62465-","G62466-","A62467-","T62468-","A62469-","A62470-","A62471-","A62472-","G62473-","T62474-","T62475-","C62476-","C62477-","A62478-","G62479-","A62480-","A62481-","A62482-","A62483-","T62484-","G62485-","T62486-","A62487-","G62488-","A62489-","A62490-","T62491-","T62492-","T62493-","T62494-","T62495-","T62496-","A62497-","A62498-","A62499-","A62500-","A62501-","G62502-","T62503-","T62504-","A62505-","T62506-","C62507-","T62508-","T62509-","T62510-","T62511-","G62512-","C62513-","T62514-","A62515-","T62516-","T62517-","A62518-","C62519-","T62520-","A62521-","A62522-","T62523-","A62524-","T62525-","C62526-","G62527-","T62528-","G62529-","G62530-","T62531-","T62532-","A62533-","G62534-","A62535-","C62536-","G62537-","C62538-","T62539-","T62540-","A62541-","T62542-","T62543-","A62544-","T62545-","T62546-","A62547-","A62548-","T62549-","A62550-","T62551-","G62552-","A62553-","G62554-","T62555-","G62556-","A62557-","T62558-","G62559-","A62560-","A62561-","A62562-","T62563-","C62564-","C62565-","A62566-","C62567-","A62568-","C62569-","C62570-","G62571-","C62572-","T62573-","T62574-","C62575-","T62576-","A62577-","G62578-","A62579-","T62580-","A62581-","T62582-","C62583-","G62584-","C62585-","T62586-","T62587-","T62588-","T62589-","A62590-","T62591-","T62592-","T62593-","C62594-","C62595-","A62596-","C62597-","A62598-","T62599-","T62600-","A62601-","G62602-","A62603-","T62604-","G62605-","G62606-","T62607-","A62608-","A62609-","A62610-","T62611-","C62612-","C62613-","A62614-","A62615-","T62616-","A62617-","G62618-","T62619-","G62620-","A62621-","A62622-","A62623-","C62624-","T62625-","A62626-","T62627-","C62628-","T62629-","T62630-","T62631-","T62632-","T62633-","A62634-","G62635-","G62636-","A62637-","A62638-","T62639-","G62640-","T62641-","A62642-","T62643-","G62644-","G62645-","A62646-","C62647-","T62648-","C62649-","G62650-","C62651-","G62652-","T62653-","T62654-","T62655-","A62656-","G62657-","A62658-","G62659-","G62660-","A62661-","G62662-","T62663-","G62664-","A62665-","A62666-","C62667-","G62668-","T62669-","C62670-","T62671-","T62672-","C62673-","G62674-","G62675-","A62676-","G62677-","T62678-","A62679-","G62680-","T62681-","A62682-","A62683-","A62684-","G62685-","G62686-","A62687-","T62688-","G62689-","A62690-","T62691-","T62692-","C62693-","G62694-","T62695-","C62696-","A62697-","A62698-","A62699-","T62700-","G62701-","A62702-","A62703-","T62704-","A62705-","A62706-","A62707-","C62708-","A62709-","A62710-","T62711-","T62712-","T62713-","C62714-","A62715-","C62716-","A62717-","A62718-","A62719-","T62720-","G62721-","G62722-","A62723-","T62724-","G62725-","T62726-","T62727-","A62728-","A62729-","T62730-","G62731-","T62732-","A62733-","T62734-","T62735-","A62736-","G62737-","T62738-","A62739-","G62740-","G62741-","A62742-","A62743-","A62744-","T62745-","T62746-","T62747-","T62748-","T62749-","T62750-","G62751-","A62752-","C62753-","G62754-","C62755-","T62756-","A62757-","G62758-","T62759-","G62760-","G62761-","A62762-","A62763-","T62764-","T62765-","G62766-","A62767-","A62768-","G62769-","A62770-","T62771-","T62772-","C62773-","T62774-","A62775-","A62776-","T62777-","G62778-","G62779-","A62780-","T62781-","G62782-","A62783-","T62784-","G62785-","T62786-","T62787-","C62788-","T62789-","A62790-","C62791-","C62792-","T62793-","A62794-","T62795-","T62796-","T62797-","C62798-","A62799-","T62800-","C62801-","C62802-","G62803-","A62804-","T62805-","A62806-","A62807-","C62808-","A62809-","T62810-","G62811-","T62812-","T62813-","A62814-","A62815-","T62816-","T62817-","T62818-","C62819-","C62820-","A62821-","A62822-","T62823-","A62824-","C62825-","C62826-","A62827-","A62828-","C62829-","G62830-","G62831-","T62832-","T62833-","T62834-","T62835-","A62836-","A62837-","T62838-","A62839-","T62840-","T62841-","T62842-","C62843-","G62844-","A62845-","T62846-","G62847-","A62848-","T62849-","A62850-","T62851-","A62852-","C62853-","G62854-","G62855-","T62856-","A62857-","G62858-","T62859-","C62860-","T62863-","C62864-","T62865-","T62866-","T62867-","C62868-","G62869-","G62870-","A62871-","C62872-","T62873-","T62874-","A62875-","T62876-","A62877-","T62878-","A62879-","G62880-","C62881-","T62882-","T62883-","A62884-","T62885-","T62886-","C62887-","C62888-","A62889-","C62890-","A62891-","A62892-","T62893-","A62894-","C62895-","G62896-","A62897-","G62898-","T62899-","C62900-","A62901-","T62902-","T62903-","A62904-","T62905-","A62906-","T62907-","A62908-","C62909-","T62910-","C62911-","C62912-","A62913-","A62914-","A62915-","A62916-","A62917-","A62918-","C62919-","A62920-","A62921-","A62922-","A62923-","T62924-","A62925-","A62926-","C62927-","T62928-","A62929-","G62930-","T62931-","A62932-","T62933-","A62934-","A62935-","A62936-","A62937-","T62938-","C62939-","T62940-","G62941-","T62942-","A62943-","T62944-","C62945-","G62946-","A62947-","A62948-","T62949-","G62950-","G62951-","G62952-","A62953-","A62954-","A62955-","A62956-","A62957-","C62958-","G62959-","A62960-","A62961-","A62962-","T62963-","T62964-","A62965-","T62966-","C62967-","G62968-","A62969-","T62970-","A62971-","T62972-","A62973-","G62974-","G62975-","T62976-","A62977-","T62978-","A62979-","G62980-","A62981-","A62982-","T62983-","C62984-","C62985-","G62986-","G62987-","A62988-","A62989-","C62990-","A62991-","T62992-","T62993-","G62994-","A62995-","A62996-","C62997-","G62998-","T62999-","A63000-","T63001-","T63002-","A63003-","A63004-","T63005-","A63006-","C63007-","T63008-","T63009-","A63010-","A63011-","T63012-","T63013-","C63014-","T63015-","T63016-","T63017-","T63018-","T63019-","C63020-","A63021-","G63022-","T63023-","G63024-","G63025-","T63026-","A63027-","A63028-","G63029-","A63030-","A63031-","C63032-","C63033-","G63034-","A63035-","T63036-","A63037-","G63038-","G63039-","T63040-","T63041-","A63042-","T63043-","T63044-","G63045-","A63046-","C63047-","A63048-","T63049-","T63050-","G63051-","T63052-","A63053-","T63054-","G63055-","G63056-","T63057-","T63058-","T63059-","T63060-","A63061-","A63062-","A63063-","T63064-","A63065-","T63066-","T63067-","C63068-","T63069-","A63070-","T63071-","A63072-","A63073-","C63074-","T63075-","T63076-","G63077-","A63078-","G63079-","A63080-","C63081-","T63082-","T63083-","G63084-","A63085-","T63086-","A63087-","G63088-","A63089-","T63090-","A63091-","T63092-","T63093-","A63094-","A63095-","T63096-","G63097-","A63098-","C63099-","G63100-","A63101-","A63102-","T63103-","T63104-","G63105-","A63106-","A63107-","A63108-","A63109-","T63110-","T63111-","A63112-","T63113-","T63114-","T63115-","T63116-","T63117-","A63118-","T63119-","C63120-","A63121-","C63122-","C63123-","A63124-","C63125-","G63126-","T63127-","G63128-","T63129-","G63130-","T63131-","T63132-","T63133-","C63134-","A63135-","G63136-","G63137-","A63138-","T63139-","C63140-","A63141-","T63142-","C63143-","G63144-","T63145-","C63146-","G63147-","A63148-","C63149-","G63150-","C63151-","C63152-","A63153-","G63154-","T63155-","T63156-","A63157-","A63158-","C63159-","C63160-","A63161-","A63162-","C63163-","C63164-","G63165-","A63166-","A63167-","T63168-","G63169-","G63170-","A63171-","G63172-","T63173-","A63174-","A63175-","A63176-","A63177-","T63178-","A63179-","A63180-","A63181-","T63182-","A63183-","T63184-","C63185-","A63186-","T63187-","T63188-","A63189-","A63190-","T63191-","A63192-","T63193-","A63194-","T63195-","G63196-","C63197-","T63198-","C63199-","T63200-","A63201-","G63202-","A63203-","T63204-","A63205-","T63206-","T63207-","A63208-","G63209-","T63210-","A63211-","T63212-","T63213-","T63214-","T63215-","T63216-","A63217-","T63218-","T63219-","A63220-","A63221-","T63222-","C63223-","C63224-","T63225-","T63226-","T63227-","G63228-","A63229-","T63230-","T63231-","A63232-","T63233-","C63234-","A63235-","T63236-","C63237-","T63238-","T63239-","C63240-","T63241-","C63242-","G63243-","T63244-","A63245-","C63246-","G63247-","C63248-","G63249-","A63250-","A63251-","T63252-","G63253-","A63254-","T63255-","T63256-","C63257-","C63258-","A63259-","T63260-","G63261-","A63262-","T63263-","C63264-","A63265-","A63266-","G63267-","A63268-","G63269-","T63270-","G63271-","A63272-","T63273-","T63274-","T63275-","G63276-","A63277-","G63278-","A63279-","A63280-","C63281-","A63282-","T63283-","C63284-","C63285-","T63286-","C63287-","C63288-","G63289-","G63290-","A63291-","G63292-","T63293-","A63294-","T63295-","T63296-","A63297-","A63298-","T63299-","G63300-","G63301-","G63302-","T63303-","T63304-","T63305-","A63306-","G63307-","T63308-","A63309-","A63310-","A63311-","C63312-","A63313-","G63314-","T63315-","C63316-","C63317-","A63318-","T63319-","C63320-","G63321-","T63322-","T63323-","G63324-","C63325-","A63326-","A63327-","T63328-","A63329-","A63330-","T63331-","A63332-","A63333-","A63334-","A63335-","G63336-","T63337-","T63338-","G63339-","T63340-","C63341-","C63342-","A63343-","A63344-","G63345-","T63346-","T63347-","A63348-","A63349-","A63350-","G63351-","G63352-","A63353-","T63354-","A63355-","T63356-","T63357-","A63358-","T63359-","G63360-","C63361-","A63362-","T63363-","T63364-","C63365-","G63366-","T63367-","T63368-","T63369-","A63370-","A63371-","A63372-","G63373-","A63374-","T63375-","A63376-","T63377-","C63378-","A63379-","C63380-","C63381-","T63382-","C63383-","A63384-","T63385-","C63386-","T63387-","A63388-","A63389-","C63390-","G63391-","G63392-","A63393-","G63394-","A63395-","C63396-","A63397-","A63398-","T63399-","T63400-","T63401-","T63402-","T63403-","T63404-","G63405-","G63406-","T63407-","A63408-","G63409-","G63410-","T63411-","T63412-","T63413-","T63414-","A63415-","G63416-","A63417-","G63418-","A63419-","C63420-","T63421-","T63422-","T63423-","G63424-","A63425-","A63426-","G63427-","C63428-","T63429-","A63430-","C63431-","T63432-","T63433-","G63434-","T63435-","T63436-","T63437-","A63438-","A63439-","C63440-","A63441-","A63442-","A63443-","G63444-","T63445-","T63446-","A63447-","T63448-","T63449-","C63450-","A63451-","T63452-","C63453-","G63454-","T63455-","C63456-","G63457-","T63458-","C63459-","T63460-","A63461-","C63462-","T63463-","A63464-","T63465-","T63466-","C63467-","T63468-","A63469-","T63470-","T63471-","T63472-","A63473-","A63474-","T63475-","T63476-","T63477-","T63478-","G63479-","T63480-","A63481-","G63482-","T63483-","T63484-","A63485-","A63486-","T63487-","T63488-","T63489-","A63490-","T63491-","C63492-","A63493-","C63494-","A63495-","T63496-","A63497-","T63498-","C63499-","A63500-","C63501-","A63502-","T63503-","T63504-","A63505-","A63506-","A89103-","A89104-","A89105-","G89148-","T89149-","C89150-","A89151-","T89166-","C89229-","A89230-","G89231-","T89232-","G89233-","T89234-","T89235-","A89373-","C89374-","T89375-","T89376-","A89377-","T89378-","A89379-","T89380-","T89381-","C89382-","G89383-","T89384-","G89385-","T89386-","C89387-","T89388-","A89389-","G89390-","T89391-","A89392-","G89393-","A89394-","T89700-","A194548-","G194586-","T194587-","T194588-","G194589-","T194590-","C194591-","T194592-","A194593-","T194594-","C194595-","G194596-","T194597-","G194598-","T194599-"],"OPG002":["K31-","C32-","K33-","D34-","N35-","E36-","Y37-"],"OPG002_dup":["C44-","L45-","S46-","C47-"],"OPG057":["N267D"],"OPG082":["T259-","P260-","K261-","T262-","F263-","T264-","P265-","L266-","N267-","A268-","S269-","P270-","V277-","F328-","I329-","K330-","E331-","N332-","I333-","I334-","W335-","K336-","G337-","I338-","Y339-","T340-","F348-","P349-","V350-","P351-","T352-","T357-","N358-","K359-","K360-","K361-","V369-","N370-","S371-","Q372-"]},"labels":{"aa":"OPG002: K31-, C32-, K33-, D34-, N35-, E36-, Y37-; OPG002_dup: C44-, L45-, S46-, C47-; OPG057: N267D; OPG082: T259-, P260-, K261-, T262-, F263-, T264-, P265-, L266-, N267-, A268-, S269-, P270-, V277-, F328-, I329-, K330-, E331-, N332-, I333-, I334-, W335-, K336-, G337-, I338-, Y339-, T340-, F348-, P349-, V350-, P351-, T352-, T357-, N358-, K359-, K360-, K361-, V369-, N370-, S371-, Q372-"}},"children":[{"name":"OQ672577","node_attrs":{"div":7,"accession":"OQ672577","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"13022023_anal"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672577/2023-02-13"},"date":{"value":"2023-02-13"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-61794G","-61795G","-61796C","-61797A","-61798T","-61815A","-61816G","-61817T","-61818A","-61819C","-61820A","-61821A","-61822G","-61823T","-61824G","-61825G","-61826C","-61827T","-61828G","-61829C","-61830T","-61831A","-61832T","-61833T","-61834T","-61835C","-61836G","-61837G","-61838C","-61839T","-61840G","-61841C","-61842C","-61843A","-61844G","-61845A","-61846G","-61847T","-61848G","-61849T","-61850C","-61851C","-61852A","-61853A","-61854T","-61855T","-61856C","-61857T","-61858A","-61859C","-61860C","-61861G","-61862T","-61863T","-61864G","-61865T","-61866T","-61867A","-61868C","-61869T","-61870C","-61871C","-61872A","-61873T","-61874T","-61875A","-61876T","-61877A","-61878T","-61879A","-61880T","-61881T","-61882C","-61883C","-61884T","-61885T","-61886G","-61887A","-61888A","-61889T","-61890A","-61891A","-61892C","-61893C","-61894T","-61895T","-61896C","-61897A","-61898T","-61899A","-61900G","-61901C","-61902T","-61903A","-61904T","-61905T","-61906T","-61907T","-61908A","-61909A","-61910T","-61911A","-61912G","-61913G","-61914A","-61915T","-61916C","-61917T","-61918A","-61919T","-61920A","-61921T","-61922G","-61923A","-61924T","-61925C","-61926A","-61927G","-61928T","-61929G","-61930T","-61931T","-61932T","-61933A","-61934A","-61935G","-61936C","-61937C","-61938A","-61939T","-61940A","-61941G","-61942C","-61943A","-61944C","-61945A","-61946A","-61947T","-61948T","-61949T","-61950T","-61951C","-61952T","-61953A","-61954A","-61955T","-61956A","-61957C","-61958G","-61961A","-61962C","-61963G","-61964T","-61965G","-61966A","-61967T","-61968T","-61969T","-61970T","-61971A","-61972T","-61973C","-61974A","-61975A","-61976A","-61977C","-61978A","-61979T","-61980G","-61981A","-61982C","-61983A","-61984T","-61985T","-61986T","-61987T","-61988C","-61989C","-61990T","-61991T","-61992G","-61993T","-61994A","-61995T","-61996C","-61997C","-61998A","-61999T","-62000T","-62001T","-62002C","-62003G","-62004T","-62005T","-62006T","-62007A","-62008A","-62009T","-62010G","-62011A","-62012C","-62013A","-62014A","-62015A","-62016C","-62017A","-62018T","-62019T","-62020T","-62021T","-62022T","-62023G","-62024T","-62025T","-62026G","-62027G","-62028T","-62029G","-62030T","-62031A","-62032A","-62033T","-62034A","-62035A","-62036A","-62037A","-62038A","-62039A","-62040A","-62041A","-62042T","-62043T","-62044A","-62045T","-62046T","-62047T","-62048A","-62049A","-62050T","-62051T","-62052T","-62053T","-62054T","-62055C","-62056A","-62057T","-62058T","-62059A","-62060A","-62061T","-62062A","-62064G","-62066A","-62067T","-62068T","-62069T","-62070G","-62071A","-62072C","-62073G","-62074T","-62075A","-62076T","-62077G","-62078T","-62079A","-62080G","-62081C","-62082G","-62083T","-62084A","-62085C","-62086A","-62087A","-62088A","-62089A","-62090T","-62091T","-62092A","-62093T","-62094C","-62095G","-62096T","-62097T","-62098C","-62099C","-62100T","-62101G","-62102G","-62103T","-62104A","-62105T","-62106A","-62107T","-62108A","-62109G","-62110A","-62111T","-62112A","-62113A","-62114A","-62115G","-62116A","-62117G","-62118T","-62119C","-62120C","-62121T","-62122A","-62123T","-62124A","-62125T","-62126A","-62127T","-62128T","-62129T","-62130G","-62131A","-62132A","-62133A","-62134A","-62135T","-62136C","-62137G","-62138T","-62139T","-62140A","-62141C","-62142G","-62143G","-62144T","-62145T","-62146C","-62147G","-62148A","-62149T","-62150T","-62151A","-62152A","-62153A","-62154C","-62155T","-62156T","-62157T","-62158A","-62159A","-62160T","-62161G","-62162A","-62163T","-62164T","-62165G","-62166C","-62167A","-62168T","-62169T","-62170G","-62171T","-62172G","-62173A","-62174A","-62175T","-62176A","-62177T","-62178A","-62179T","-62180C","-62181A","-62182T","-62183T","-62184A","-62185G","-62186G","-62187A","-62188T","-62189T","-62190T","-62191A","-62192A","-62193C","-62194T","-62195C","-62196C","-62197T","-62198T","-62199G","-62200A","-62201C","-62202T","-62203A","-62204T","-62205C","-62206A","-62207T","-62208G","-62209G","-62210C","-62211G","-62212G","-62213T","-62214G","-62215C","-62216C","-62217A","-62221A","-62222T","-62223T","-62228T","-62229C","-62230A","-62231A","-62232A","-62233A","-62234G","-62235C","-62236A","-62237T","-62238T","-62239A","-62240A","-62241T","-62242A","-62243C","-62244A","-62245G","-62246T","-62247T","-62248A","-62249T","-62250G","-62251C","-62252A","-62253G","-62254A","-62255T","-62256C","-62257G","-62258C","-62259A","-62260G","-62264G","-62265A","-62266A","-62267C","-62268G","-62269G","-62270T","-62271T","-62272A","-62273T","-62274A","-62275G","-62276C","-62277A","-62278T","-62279C","-62280C","-62281A","-62282C","-62283C","-62284A","-62285T","-62286T","-62287T","-62288A","-62289T","-62290A","-62303A","-62304T","-62309G","-62310A","-62311A","-62312T","-62313A","-62314T","-62315G","-62316T","-62317G","-62318A","-62319C","-62320A","-62321A","-62322C","-62324T","-62325C","-62326C","-62327T","-62328A","-62329G","-62330T","-62331T","-62332G","-62333T","-62352A","-62353C","-62354A","-62355A","-62356T","-62357G","-62389G","-62390A","-62391C","-62392T","-62393T","-62413C","-62414T","-62416G","-62417A","-62420T","-62421G","-62422A","-62423T","-62424T","-62425A","-62426T","-62427T","-62428C","-62429T","-62430A","-62431T","-62432A","-62474T","-62475T","-62484T","-62492T","-62493T","-62494T","-62495T","-62496T","-62497A","-62498A","-62499A","-62500A","-62501A","-62502G","-62503T","-62504T","-62505A","-62506T","-62507C","-62508T","-62509T","-62510T","-62511T","-62512G","-62513C","-62514T","-62515A","-62516T","-62517T","-62518A","-62519C","-62520T","-62521A","-62522A","-62523T","-62524A","-62525T","-62526C","-62527G","-62528T","-62529G","-62530G","-62531T","-62532T","-62543T","-62546T","-62547A","-62548A","-62549T","-62550A","-62551T","-62552G","-62553A","-62554G","-62555T","-62556G","-62557A","-62558T","-62559G","-62560A","-62561A","-62562A","-62563T","-62564C","-62565C","-62566A","-62567C","-62568A","-62569C","-62570C","-62571G","-62572C","-62573T","-62575C","-62579A","-62580T","-62581A","-62582T","-62583C","-62584G","-62585C","-62586T","-62587T","-62588T","-62589T","-62590A","-62591T","-62592T","-62593T","-62594C","-62595C","-62596A","-62597C","-62598A","-62599T","-62600T","-62601A","-62602G","-62606G","-62607T","-62608A","-62609A","-62610A","-62611T","-62612C","-62616T","-62617A","-62618G","-62619T","-62620G","-62621A","-62627T","-62632T","-62633T","-62634A","-62635G","-62636G","-62637A","-62638A","-62639T","-62640G","-62641T","-62642A","-62643T","-62653T","-62694G","-62695T","-62697A","-62698A","-62700T","-62705A","-62706A","-62707A","-62708C","-62709A","-62710A","-62711T","-62712T","-62713T","-62714C","-62715A","-62716C","-62717A","-62718A","-62719A","-62720T","-62721G","-62722G","-89103A","-89104A","-89105A","-89148G","-89149T","-89150C","-89151A","-89229C","-89230A","-89231G","-89232T","-89233G","-89234T","-89235T","-89373A","-89374C","-89375T","-89376T","-89377A","-89378T","-89379A","-89380T","-89381T","-89382C","-89383G","-89384T","-89385G","-89386T","-89387C","-89388T","-89389A","-89390G","-89391T","-89392A","-89393G","-89394A","-89700T","C194600-","C194601-","T194602-"],"OPG002_dup":["P48-"]},"labels":{"aa":"OPG002_dup: P48-"}}},{"name":"OQ672576","node_attrs":{"div":8,"accession":"OQ672576","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"08022023_anal"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672576/2023-02-08"},"date":{"value":"2023-02-08"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T70389G","-194548A"],"OPG089":["M175R"]},"labels":{"aa":"OPG089: M175R"}}},{"name":"OQ672579","node_attrs":{"div":7,"accession":"OQ672579","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"28022023_anal"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672579/2023-02-28"},"date":{"value":"2023-02-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["-62294A","-62374T","-62375T","-63506A","C70785-","G70786-","T70787-","A70788-","T70789-","A70790-","T70829-","C70830-","G70880-","T70881-","G70882-","C70883-","C70884-","G70885-","T70886-","T70887-","A70888-","C70889-","C70890-","C70891-","T70892-","G70893-","C70894-","C70895-","G70907-","C70908-","A70909-","T70910-","T70911-","A70912-","G70913-","A70914-","A70915-","C70916-","C70917-","A70918-","C70919-","G70920-","T70921-","G70940-","A70941-","A70942-","T70963-","T70970-","T70971-","C70972-","G70973-","A70974-","A70975-","A70976-","A70977-","T70978-","A70979-","C70980-","T70981-","A70982-","A70983-","A70984-","T70985-","C70986-","A70987-","T71023-","G71024-","G71025-","A71026-","T71027-","A71028-","T71029-","T71030-","C71031-","T71032-","A71033-","A71034-","C71035-","G71036-","A71037-","A71038-","A71039-","A71040-","C71041-","T71042-","G71043-","T71044-","A71045-","A71046-","C71047-","A71048-","C71049-","C71050-","A71051-","T71052-","A71053-","G71054-","T71055-","G71056-","T71057-","T71058-","C71059-","G71060-","G71061-","C71062-","A71063-","T71064-","C71065-","T71066-","A71067-","T71068-","A71069-","A71070-","G71071-","G71072-","A71073-","T71074-","A71075-","A71076-","T71077-","T71078-","T71079-","A71080-","C71081-","T71082-","A71083-","C71084-","T71085-","G71086-","A71087-","G71088-","T71089-","A71090-","T71091-","A71092-","A71129-","C71130-","C71131-","A71132-","A71133-","T71134-","A71135-","C71136-","T71137-","A71138-","A71139-","A71140-","A71141-","G71142-","T71143-","G71144-","A71145-","T71146-","A71147-","A71148-","T71149-","A71150-","T71172-","T71173-","A71174-","A71175-","A71176-","A71177-","A71178-","A71179-","T71180-","G71181-","G71182-","T71183-","G71184-","T71185-","T71186-","C71187-","C71188-","A71189-","G71190-","C71191-","T71192-","C71193-","G71194-","T71195-","G71196-","T71197-","G71198-","T71199-","T71200-","C71201-","T71202-","A71203-","C71204-","A71205-","T71206-","G71207-","C71208-","G71209-","G71210-","C71211-","A71212-","A71213-","A71214-","G71215-","A71216-","T71217-","A71218-","T71219-","T71220-","T71221-","C71222-","T71223-","C71224-","A71225-","C71226-","G71227-","A71228-","A71229-","C71230-","G71231-","A71232-","T71233-","A71234-","T71235-","A71236-","A71237-","A71238-","T71239-","T71240-","G71241-","A71242-","T71243-","T71244-","A71245-","T71246-","A71247-","C71248-","G71249-","A71250-","A71251-","A71252-","A71253-","A71254-","A71255-","A71256-","T71257-","C71258-","A71259-","T71260-","T71261-","A71262-","A71263-","A71264-","G71265-","G71266-","A71267-","T71268-","G71269-","T71270-","A71271-","C71272-","T71273-","A71274-","G71275-","T71276-","C71277-","A71278-","G71279-","T71280-","G71281-","T71282-","A71283-","A71284-","A71285-","G71286-","A71287-","A71288-","C71289-","G71290-","A71291-","A71292-","T71293-","G71294-","T71295-","T71296-","G71297-","T71298-","A71299-","G71300-","G71301-","T71302-","T71303-","A71304-","A71305-","A71306-","A71307-","T71308-","T71309-","A71310-","T71311-","C71312-","T71313-","A71314-","C71315-","A71316-","C71317-","A71318-","A71319-","A71320-","T71321-","A71322-","G71323-","A71324-","A71325-","C71326-","C71327-","T71328-","C71329-","A71330-","A71331-","C71332-","G71333-","T71334-","A71335-","A71336-","C71337-","T71338-","T71339-","A71340-","A71341-","C71342-","A71343-","G71344-","T71345-","G71346-","C71347-","A71348-","A71349-","C71350-","C71351-","T71352-","C71353-","T71354-","A71355-","T71356-","T71357-","G71358-","G71359-","A71360-","T71361-","A71362-","T71363-","A71364-","A71365-","A71366-","C71367-","T71368-","A71369-","A71370-","T71371-","G71372-","G71373-","A71374-","T71375-","C71376-","C71377-","G71378-","G71379-","T71380-","T71381-","A71382-","A71383-","T71384-","T71385-","T71386-","T71387-","A71388-","T71389-","C71390-","A71391-","A71392-","G71393-","A71394-","C71395-","A71396-","T71397-","A71398-","T71399-","G71400-","C71401-","G71402-","C71403-","C71404-","T71405-","A71406-","G71407-","A71408-","G71409-","G71410-","T71411-","T71412-","C71413-","T71414-","A71415-","T71416-","T71417-","A71418-","T71419-","T71420-","T71421-","T71422-","T71423-","A71424-","T71425-","T71426-","G71517-","T71518-","A71519-","G71520-","T71521-","T71522-","G71523-","A71524-","A71525-","T71526-","C71527-","T71528-","A71529-","C71530-","C71531-","T71532-","A71533-","T71534-","A71535-","G71536-","A71537-","A71538-","A71539-","A71540-","G71541-","G71542-","A71543-","G71544-","T71545-","T71546-","A71547-","G71548-","A71549-","A71550-","T71551-","A71552-","G71553-","T71554-","C71555-","C71556-","C71557-","A71558-","T71559-","T71560-","G71561-","G71562-","A71563-","T71564-","A71565-","G71566-","A71567-","T71568-","T71569-","T71570-","T71571-","T71572-","T71573-","G71574-","A71575-","A71576-","G71577-","G71578-","A71579-","T71580-","A71581-","T71582-","C71583-","T71584-","T71585-","A71586-","G71587-","T71588-","G71589-","C71590-","A71591-","A71592-","A71593-","A71594-","G71595-","T71596-","A71597-","T71598-","A71599-","C71600-","A71601-","T71602-","G71603-","T71604-","T71605-","A71606-","G71607-","A71608-","G71609-","A71610-","A71611-","T71612-","A71613-","T71614-","T71615-","C71616-","A71617-","A71618-","G71619-","T71620-","T71621-","A71622-","T71623-","G71624-","A71625-","A71626-","A71627-","A71628-","T71629-","A71630-","G71631-","C71632-","A71633-","G71634-","C71635-","T71636-","G71637-","A71638-","T71639-","A71640-","T71641-","G71642-","T71643-","C71644-","G71645-","T71646-","T71647-","A71648-","A71649-","C71650-","T71651-","T71652-","G71676-","G71677-","T71678-","C71679-","G71709-","C71710-","T71711-","G71712-","A71713-","A71714-","T71715-","G71716-","T71717-","T71718-","A71719-","T71720-","A71721-","A71722-","A71723-","A71724-","A71725-","T71726-","G71727-","C71728-","C71729-","G71730-","G71731-","T71732-","A71733-","T71734-","T71735-","G71736-","A71737-","T71738-","A71739-","C71740-","A71741-","T71742-","C71743-","G71744-","T71745-","C71746-","T71747-","A71748-","A71749-","A71750-","C71751-","G71752-","A71753-","A71754-","T71755-","A71756-","T71757-","T71758-","A71759-","G71760-","G71761-","T71762-","A71763-","A71764-","A71765-","G71766-","A71767-","T71768-","A71769-","T71770-","T71771-","T71772-","T71773-","T71774-","C71775-","T71776-","G71777-","A71778-","G71779-","C71780-","C71781-","A71782-","A71783-","A71784-","A71785-","C71786-","T71787-","T71788-","T71789-","A71790-","C71791-","A71792-","G71793-","A71794-","T71795-","G71796-","A71797-","T71798-","A71799-","A71800-","T71801-","A71802-","G71803-","A71804-","T71805-","G71806-","G71807-","A71808-","T71809-","A71810-","A71811-","A71812-","G71813-","C71856-","C71910-","T71911-","T71912-","T71913-","T71914-","T71915-","C71916-","T71917-","T71918-","A71919-","A71920-","C71921-","G71922-","T71923-","T71924-","G71925-","T71926-","T71927-","T71928-","G71929-","C71930-","C71931-","A71932-","T71933-","C71934-","A71935-","C71936-","T71937-","C71938-","T71939-","C71940-","A71941-","T71942-","A71943-","A71944-","T71945-","G71946-","T71947-","A71948-","A71949-","A71950-","G71951-","A71952-","T71953-","A71954-","T71955-","T71956-","C71957-","T71958-","A71959-","A71960-","A71961-","A71962-","T71963-","G71964-","G71965-","T71966-","A71967-","A71968-","A71969-","C71970-","T71971-","T71972-","T71973-","T71974-","G71975-","C71976-","A71977-","T71978-","A71979-","T71980-","C71981-","G71982-","G71983-","A71984-","T71985-","G71986-","C71987-","A71988-","G71989-","A71990-","A71991-","A71992-","T71993-","T71994-","G71995-","G71996-","T71997-","A71998-","T71999-","A72000-","A72001-","A72002-","T72003-","G72004-","T72005-","T72006-","G72007-","T72008-","A72009-","A72010-","T72011-","T72012-","G72013-","T72014-","A72015-","T72016-","T72017-","A72018-","T72019-","T72020-","T72021-","C72022-","C72023-","C72024-","G72025-","T72026-","C72027-","A72028-","A72029-","T72030-","G72031-","G72032-","A72033-","C72034-","T72035-","A72036-","G72037-","T72038-","C72039-","A72040-","C72041-","A72042-","G72043-","C72044-","T72045-","C72046-","C72047-","A72048-","T72049-","C72050-","A72051-","G72052-","T72053-","T72054-","T72055-","T72056-","A72057-","T72058-","A72059-","T72060-","C72061-","C72062-","T72063-","T72064-","T72065-","A72066-","G72067-","A72068-","G72069-","T72070-","A72071-","T72072-","T72073-","T72074-","C72075-","T72076-","C72077-","A72078-","C72079-","T72080-","C72081-","G72082-","T72083-","G72084-","T72085-","C72086-","T72087-","A72088-","G72089-","C72090-","A72091-","T72092-","T72093-","C72094-","T72095-","A72096-","G72097-","A72098-","G72099-","C72100-","A72101-","T72102-","T72103-","C72104-","C72105-","A72106-","T72107-","G72108-","A72109-","T72110-","C72111-","T72112-","G72113-","T72114-","T72115-","T72116-","A72117-","T72118-","C72119-","G72120-","T72121-","T72122-","G72123-","A72124-","T72125-","A72126-","T72127-","T72128-","G72129-","G72130-","C72131-","C72132-","G72133-","G72134-","A72135-","A72136-","A72137-","G72138-","A72139-","T72140-","A72141-","G72142-","A72143-","T72144-","T72145-","T72146-","T72147-","T72148-","T72149-","A72150-","T72151-","T72152-","T72153-","T72154-","T72155-","T72156-","A72157-","T72158-","T72159-","A72160-","T72161-","A72162-","T72163-","T72164-","A72165-","C72166-","T72167-","A72168-","T72169-","T72170-","G72171-","G72172-","C72173-","A72174-","A72175-","T72176-","T72177-","G72178-","T72179-","A72180-","G72181-","A72182-","T72183-","A72184-","T72185-","A72186-","A72187-","C72188-","T72189-","T72190-","C72191-","T72192-","G72193-","G72194-","T72195-","A72196-","A72197-","A72198-","T72199-","A72200-","T72201-","T72202-","T72203-","T72204-","T72205-","C72206-","T72207-","A72208-","C72209-","C72210-","T72211-","T72212-","T72213-","T72214-","C72215-","A72216-","A72217-","T72218-","C72219-","T72220-","C72221-","T72222-","T72223-","C72224-","T72225-","A72226-","T72227-","T72228-","T72229-","T72230-","C72231-","A72232-","A72233-","G72234-","C72235-","C72236-","G72237-","G72238-","C72239-","T72240-","A72241-","T72242-","A72243-","T72244-","A72245-","T72246-","T72247-","C72248-","T72249-","G72250-","C72251-","T72252-","A72253-","T72254-","A72255-","T72256-","T72257-","G72258-","T72259-","T72260-","A72261-","C72262-","T72263-","A72264-","G72265-","T72266-","A72267-","T72268-","C72269-","A72270-","A72271-","T72272-","A72273-","C72274-","C72275-","T72276-","T72277-","T72278-","T72279-","C72280-","T72281-","G72282-","G72283-","C72284-","T72285-","A72286-","A72287-","G72288-","A72289-","A72290-","G72291-","T72292-","C72293-","A72294-","T72295-","A72296-","T72297-","G72298-","T72299-","G72300-","G72301-","T72302-","A72303-","T72304-","T72305-","C72306-","A72307-","C72308-","T72309-","A72310-","T72311-","A72312-","T72313-","C72314-","A72315-","G72316-","T72317-","T72318-","T72319-","T72320-","A72321-","A72322-","C72323-","T72324-","G72325-","G72326-","T72327-","A72328-","G72329-","T72330-","T72331-","C72332-","C72333-","A72334-","T72335-","T72336-","A72337-","G72338-","C72339-","C72340-","T72341-","T72342-","T72343-","C72344-","C72345-","A72346-","C72347-","T72348-","T72349-","C72350-","T72351-","G72352-","C72353-","A72354-","G72355-","A72356-","A72357-","T72358-","A72359-","A72360-","T72361-","T72362-","A72363-","G72364-","A72365-","A72366-","A72367-","T72368-","T72369-","G72370-","G72371-","T72372-","T72373-","C72374-","T72375-","T72376-","T72377-","A72378-","C72379-","C72380-","A72381-","G72382-","A72383-","A72384-","A72385-","A72386-","T72387-","C72388-","C72389-","A72390-","G72391-","C72392-","T72393-","A72394-","-194548A","-194549A"],"OPG080":["A75-"],"OPG089":["S307F","I309-","P310-","S322-","V339-","P340-","L341-","P342-","C343-","Q344-","L349-","E350-","P351-","R352-","K353-","E359-"],"OPG091":["L163-"],"OPG092":["A186-","G187-","F188-","S189-","G190-","K191-","E192-","P193-","I194-","S195-","N196-","Y197-","S198-","A199-","E200-","V201-","E202-","R203-","L204-","M205-","E206-","L207-","P208-","V209-","K210-","T211-","D212-","I213-","V214-","N215-","T216-","T217-","Y218-","D219-","F220-","L221-","A222-","R223-","K224-","G225-","I226-","D227-","T228-","S229-","N230-","N231-","I232-","A233-","E234-","Y235-","I236-","A237-","G238-","L239-","K240-","I241-","E242-","E243-","I244-","E245-","K246-","V247-","E248-","K249-","Y250-","L251-","P252-","E253-","V254-","I255-","S256-","T257-","I258-","A259-","N260-","S261-","N262-","I263-","I264-","K265-","N266-","K267-","K268-","S269-","I270-","F271-","P272-","A273-","N274-","I275-","N276-","D277-","K278-","Q279-","I280-","M281-","E282-","C283-","S284-","R285-","M286-","L287-","D288-","T289-","S290-","E291-","K292-","Y293-","S294-","K295-","G296-","Y297-","K298-","T299-","D300-","G301-","A302-","V303-","T304-","S305-","P306-","L307-","T308-","G309-","N310-","N311-","T312-","I313-","T314-","T315-","F316-","I317-","P318-","I319-","S320-","A321-","S322-","D323-","M324-","Q325-","K326-","F327-","T328-","I329-","L330-","E331-","Y332-","L333-","Y334-","I335-","M336-","R337-","V338-","M339-","A340-","N341-","N342-","V343-","K344-","K345-","K346-","V365-"],"OPG109":["L19-","L20-","D21-","T22-","N23-","I24-","S25-","D100-"]},"labels":{"aa":"OPG080: A75-; OPG089: S307F, I309-, P310-, S322-, V339-, P340-, L341-, P342-, C343-, Q344-, L349-, E350-, P351-, R352-, K353-, E359-; OPG091: L163-; OPG092: A186-, G187-, F188-, S189-, G190-, K191-, E192-, P193-, I194-, S195-, N196-, Y197-, S198-, A199-, E200-, V201-, E202-, R203-, L204-, M205-, E206-, L207-, P208-, V209-, K210-, T211-, D212-, I213-, V214-, N215-, T216-, T217-, Y218-, D219-, F220-, L221-, A222-, R223-, K224-, G225-, I226-, D227-, T228-, S229-, N230-, N231-, I232-, A233-, E234-, Y235-, I236-, A237-, G238-, L239-, K240-, I241-, E242-, E243-, I244-, E245-, K246-, V247-, E248-, K249-, Y250-, L251-, P252-, E253-, V254-, I255-, S256-, T257-, I258-, A259-, N260-, S261-, N262-, I263-, I264-, K265-, N266-, K267-, K268-, S269-, I270-, F271-, P272-, A273-, N274-, I275-, N276-, D277-, K278-, Q279-, I280-, M281-, E282-, C283-, S284-, R285-, M286-, L287-, D288-, T289-, S290-, E291-, K292-, Y293-, S294-, K295-, G296-, Y297-, K298-, T299-, D300-, G301-, A302-, V303-, T304-, S305-, P306-, L307-, T308-, G309-, N310-, N311-, T312-, I313-, T314-, T315-, F316-, I317-, P318-, I319-, S320-, A321-, S322-, D323-, M324-, Q325-, K326-, F327-, T328-, I329-, L330-, E331-, Y332-, L333-, Y334-, I335-, M336-, R337-, V338-, M339-, A340-, N341-, N342-, V343-, K344-, K345-, K346-, V365-; OPG109: L19-, L20-, D21-, T22-, N23-, I24-, S25-, D100-"}}},{"name":"OQ672578","node_attrs":{"div":7,"accession":"OQ672578","author":{"author":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K.","value":"Mertes,H.,Rezende,A.M.,Naesens,R.,de Block,T.,Michiels,J.,Coppens,J.,Van Dijck,C.,Bomans,P.,Arien,K.,Bottieau,E.,Van Esbroeck,M.,Liesenborghs,L.,Vercauteren,K."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"23022023_anal"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Tropica Medicine, Department of Clinical Sciences"},"strain_display":{"value":"Belgium/OQ672578/2023-02-23"},"date":{"value":"2023-02-23"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T2662-","C47694-","T49712-","G61626-","A61627-","G61628-","C61629-","T61630-","T61631-","A61674-","A61675-","T61676-","C61677-","G61678-","G61679-","A61680-","G61681-","A61682-","A61683-","T61684-","G61685-","T61686-","T61687-","T61688-","C61689-","C61690-","C61691-","A61692-","T61693-","T61694-","T61695-","T61696-","T61697-","A61698-","G61699-","G61700-","A61701-","T61702-","T61703-","A61704-","A61705-","C61706-","A61707-","T61708-","A61709-","G61710-","T61740-","A61741-","G61742-","T61743-","T61744-","A61764-","T61765-","T61766-","T61767-","G61768-","A61769-","T61770-","A61771-","A61791-","A61792-","T61793-","A61799-","A61800-","T61801-","C61802-","C61803-","G61804-","G61805-","A61806-","T61807-","G61808-","T61809-","T61810-","G61811-","T61812-","G61813-","T61814-","A62296-","A62297-","A62298-","T62299-","T62300-","A62301-","G62302-","T62358-","T62359-","T62360-","C62361-","T62362-","T62363-","A62364-","C62365-","A62366-","T62367-","A62368-","T62369-","T62370-","T62371-","T62372-","G88521-","A88522-","T88523-","C88524-","T88525-","C88526-","T88527-","A88528-","T88529-","A88530-","A88531-","T88532-","A88533-","T88534-","C88535-","T88536-","A88537-","G88538-","T88539-","T88540-","T88541-","C88542-","T88543-","T88544-","G88545-","C88546-","G88547-","T88548-","T88549-","T88550-","C88551-","A88552-","C88553-","A88554-","A88555-","A88556-","C88557-","A88558-","C88559-","A88560-","G88561-","G88562-","C88563-","T88564-","C88565-","G88566-","T88567-","C88568-","T88569-","C88570-","T88571-","C88572-","G88573-","C88574-","G88575-","A88576-","T88577-","G88578-","A88579-","G88580-","A88581-","T88582-","C88583-","T88584-","G88585-","T88586-","A88587-","T88588-","A88589-","G88590-","T88591-","A88592-","A88593-","C88594-","T88595-","A88596-","T88597-","G88598-","T88599-","A88600-","A88601-","A88602-","T88603-","G88604-","A88605-","T88606-","A88607-","A88608-","C88609-","T88610-","A88611-","G88612-","A88613-","T88614-","A88615-","G88616-","A88617-","A88618-","A88619-","G88620-","A88621-","T88622-","G88623-","T88624-","A88625-","G88626-","C88627-","T88628-","A88629-","T88630-","A88631-","T88632-","A88633-","G88634-","A88635-","T88636-","G88637-","A88638-","C88639-","G88640-","A88641-","T88642-","C88643-","C88644-","T88645-","T88646-","T88647-","A88648-","A88649-","G88650-","A88651-","G88652-","A88653-","G88654-","G88655-","T88656-","A88657-","T88658-","A88659-","A88660-","T88661-","A88662-","A88663-","C88664-","T88665-","T88666-","T88667-","A88668-","C88669-","C88670-","C88671-","C88672-","A88673-","A88674-","T88675-","C88676-","A88677-","G88678-","A88679-","T88680-","A88681-","G88682-","A88683-","C88684-","T88685-","G88686-","T88687-","T88688-","G88689-","T88690-","T88691-","A88692-","T88693-","G88694-","G88695-","T88696-","C88697-","T88698-","T88699-","C88700-","G88701-","G88702-","A88703-","A88704-","A88705-","A88706-","A88707-","G88708-","A88709-","A88710-","T88711-","T88712-","T88713-","T88714-","T88715-","A88716-","T88717-","A88718-","A88719-","A88720-","T88721-","T88722-","T88723-","T88724-","T88725-","C88726-","C88727-","A88728-","G88729-","T88730-","A88731-","T88732-","T88733-","T88734-","T88735-","C88736-","T88737-","A88738-","A88739-","A88740-","T88741-","A88742-","T88743-","A88744-","C88745-","G88746-","T88747-","A88748-","C88749-","T88750-","T88751-","G88752-","A88753-","T88754-","A88755-","T88756-","C88757-","T88758-","A88759-","A88760-","G88761-","A88762-","A88763-","A88764-","T88765-","C88766-","C88767-","T88768-","T88769-","A88770-","A88771-","T88772-","A88773-","A88774-","T88775-","A88776-","A88777-","T88778-","A88779-","G88780-","G88781-","A88782-","A88783-","T88784-","G88785-","G88786-","A88787-","T88788-","A88789-","A88790-","T88791-","C88792-","C88793-","G88794-","T88795-","C88796-","T88797-","A88798-","T88799-","T88800-","T88801-","T88802-","A88803-","T88804-","A88805-","A88806-","A88807-","G88808-","A88809-","A88810-","A88811-","T88812-","A88813-","C88814-","A88815-","T88816-","A88817-","T88818-","C88819-","G88820-","C88821-","A88822-","T88823-","A88824-","T88825-","T88826-","A88827-","T88828-","A88829-","C88830-","T88831-","T88832-","T88833-","T88834-","T88835-","T88836-","T88837-","T88838-","G88839-","G88840-","A88841-","A88842-","A88843-","T88844-","T88845-","G88846-","G88847-","A88848-","A88849-","T88850-","A88851-","C88852-","C88853-","G88854-","A88855-","T88856-","G88857-","T88858-","G88859-","T88860-","C88861-","T88862-","A88863-","C88864-","A88865-","T88866-","A88867-","A88868-","A88869-","T88870-","A88871-","C88872-","G88873-","C88874-","A88875-","A88876-","A88877-","G88878-","T88879-","C88880-","T88881-","A88882-","A88883-","A88884-","T88885-","A88886-","T88887-","T88888-","T88889-","T88890-","T88891-","T88892-","A88893-","G88894-","A88895-","G88896-","A88897-","A88898-","T88899-","C88900-","T88901-","T88902-","A88903-","G88904-","T88905-","T88906-","G88907-","G88908-","T88909-","C88910-","C88911-","A88912-","A88913-","A88914-","T88915-","T88916-","C88917-","T88918-","T88919-","T88920-","T88921-","C88922-","C88923-","A88924-","A88925-","G88926-","T88927-","A88928-","C88929-","G88930-","G88931-","T88932-","A88933-","A88934-","T88935-","A88936-","G88937-","A88938-","T88939-","T88940-","T88941-","T88942-","T88943-","C88944-","A88945-","T88946-","A88947-","T88948-","T88949-","G88950-","A88951-","A88952-","C88953-","G88954-","G88955-","T88956-","A88957-","T88958-","C88959-","T88960-","T88961-","C88962-","T88963-","T88964-","G88965-","A88966-","T88967-","C88968-","T88969-","C88970-","T88971-","G88972-","G88973-","T88974-","T88975-","C88976-","T88977-","A88978-","A88979-","T88980-","T88981-","C88982-","C88983-","G88984-","C88985-","A88986-","T88987-","T88988-","A88989-","A88990-","A88991-","T88992-","G88993-","A88994-","T88995-","G88996-","A88997-","A88998-","A88999-","C89000-","T89001-","A89002-","A89003-","G89004-","T89005-","C89006-","A89007-","C89008-","T89009-","A89010-","T89011-","T89012-","T89013-","T89014-","T89015-","A89016-","T89017-","A89018-","A89019-","C89020-","T89021-","A89022-","A89023-","C89024-","G89025-","A89026-","T89027-","T89028-","A89029-","C89030-","A89031-","T89032-","C89033-","A89034-","C89035-","C89036-","T89037-","C89038-","T89039-","A89040-","A89041-","C89042-","A89043-","T89044-","C89045-","A89046-","T89047-","C89048-","A89049-","T89050-","T89051-","T89052-","A89053-","C89054-","C89055-","A89056-","G89057-","G89058-","A89059-","T89060-","A89061-","C89062-","T89063-","G89064-","A89065-","T89066-","C89067-","T89068-","T89069-","C89070-","T89071-","T89072-","T89073-","T89074-","G89075-","T89076-","C89077-","G89078-","T89079-","A89080-","A89081-","A89082-","T89083-","A89084-","C89085-","A89086-","T89087-","G89088-","T89089-","C89090-","T89091-","A89092-","A89093-","T89094-","G89095-","T89096-","G89097-","T89098-","T89099-","A89100-","A89101-","A89102-","A89106-","A89107-","G89108-","A89109-","T89110-","C89111-","A89112-","T89113-","A89114-","C89115-","A89116-","A89117-","G89118-","T89119-","T89120-","A89121-","T89122-","A89123-","C89124-","G89125-","T89126-","C89127-","A89128-","T89129-","T89130-","T89131-","C89132-","A89133-","T89134-","C89135-","T89136-","G89137-","T89138-","A89139-","G89140-","T89141-","A89142-","T89143-","T89144-","C89145-","T89146-","T89147-","T89152-","T89153-","G89154-","A89155-","A89156-","G89157-","G89158-","A89159-","T89160-","A89161-","A89162-","A89163-","C89164-","T89165-","G89167-","T89168-","A89169-","C89170-","T89171-","A89172-","A89173-","T89174-","C89175-","T89176-","C89177-","T89178-","T89179-","C89180-","T89181-","T89182-","T89183-","A89184-","A89185-","C89186-","A89187-","G89188-","T89189-","C89190-","T89191-","G89192-","T89193-","T89194-","C89195-","A89196-","A89197-","A89198-","T89199-","T89200-","T89201-","A89202-","T89203-","A89204-","T89205-","C89206-","C89207-","T89208-","A89209-","T89210-","A89211-","T89212-","A89213-","T89214-","G89215-","A89216-","A89217-","A89218-","A89219-","A89220-","A89221-","T89222-","A89223-","G89224-","C89225-","A89226-","A89227-","C89228-","T89236-","G89237-","A89238-","T89239-","C89240-","A89241-","T89242-","C89243-","C89244-","G89245-","C89246-","G89247-","T89248-","C89249-","A89250-","A89251-","T89252-","A89253-","T89254-","T89255-","C89256-","T89257-","G89258-","T89259-","T89260-","C89261-","T89262-","A89263-","T89264-","C89265-","G89266-","T89267-","A89268-","G89269-","T89270-","G89271-","T89272-","A89273-","T89274-","A89275-","A89276-","C89277-","A89278-","A89279-","T89280-","C89281-","T89282-","T89283-","A89284-","T89285-","A89286-","T89287-","C89288-","T89289-","T89290-","C89291-","T89292-","T89293-","C89294-","T89295-","G89296-","T89297-","G89298-","A89299-","T89300-","A89301-","G89302-","T89303-","C89304-","G89305-","A89306-","T89307-","A89308-","C89309-","G89310-","T89311-","T89312-","A89313-","T89314-","A89315-","A89316-","A89317-","G89318-","G89319-","T89320-","T89321-","G89322-","A89323-","T89324-","A89325-","A89326-","C89327-","G89328-","A89329-","A89330-","A89331-","A89332-","T89333-","A89334-","T89335-","T89336-","T89337-","T89338-","T89339-","A89340-","T89341-","T89342-","T89343-","C89344-","G89345-","T89346-","G89347-","A89348-","A89349-","A89350-","T89351-","A89352-","A89353-","A89354-","G89355-","T89356-","C89357-","A89358-","T89359-","T89360-","G89361-","T89362-","A89363-","G89364-","G89365-","A89366-","T89367-","T89368-","T89369-","T89370-","G89371-","G89372-","T89395-","A89396-","T89397-","G89398-","A89399-","T89400-","T89401-","T89402-","T89403-","A89404-","T89405-","T89406-","T89407-","T89408-","T89409-","G89410-","G89411-","A89412-","A89413-","T89414-","G89415-","A89416-","T89417-","C89418-","T89419-","C89420-","A89421-","A89422-","T89423-","T89424-","A89425-","A89426-","A89427-","A89428-","T89429-","A89430-","G89431-","T89432-","C89433-","T89434-","C89435-","T89436-","T89437-","T89438-","A89439-","G89440-","A89441-","G89442-","T89443-","C89444-","C89445-","A89446-","T89447-","T89448-","T89449-","A89450-","A89451-","A89452-","G89453-","T89454-","T89455-","A89456-","C89457-","A89458-","A89459-","A89460-","C89461-","A89462-","A89463-","C89464-","T89465-","A89466-","G89467-","G89468-","A89469-","A89470-","A89471-","T89472-","T89473-","G89474-","G89475-","T89476-","T89477-","T89478-","A89479-","T89480-","G89481-","A89482-","T89483-","G89484-","T89485-","A89486-","T89487-","A89488-","A89489-","T89490-","T89491-","T89492-","T89493-","T89494-","T89495-","T89496-","A89497-","G89498-","T89499-","T89500-","T89501-","T89502-","T89503-","A89504-","T89505-","A89506-","G89507-","A89508-","T89509-","T89510-","C89511-","T89512-","T89513-","T89514-","A89515-","T89516-","T89517-","C89518-","T89519-","A89520-","T89521-","A89522-","C89523-","T89524-","T89525-","A89526-","A89527-","A89528-","A89529-","A89530-","A89531-","T89532-","G89533-","A89534-","A89535-","A89536-","A89537-","T89538-","A89539-","A89540-","A89541-","T89542-","A89543-","C89544-","A89545-","A89546-","A89547-","G89548-","G89549-","T89550-","T89551-","C89552-","T89553-","T89554-","G89555-","A89556-","G89557-","G89558-","G89559-","T89560-","T89561-","G89562-","T89563-","G89564-","T89565-","T89566-","A89567-","A89568-","T89569-","T89570-","G89571-","A89572-","A89573-","A89574-","G89575-","C89576-","G89577-","A89578-","T89579-","A89580-","A89581-","A89582-","T89583-","A89584-","A89585-","T89586-","C89587-","A89588-","T89589-","A89590-","A89591-","A89592-","T89593-","T89594-","A89595-","T89596-","T89597-","T89598-","C89599-","A89600-","T89601-","T89602-","A89603-","T89604-","C89605-","G89606-","C89607-","G89608-","A89609-","T89610-","A89611-","T89612-","C89613-","C89614-","G89615-","T89616-","T89617-","A89618-","A89619-","G89620-","T89621-","T89622-","T89623-","G89624-","T89625-","A89626-","T89627-","C89628-","G89629-","T89630-","A89631-","A89632-","T89633-","G89634-","G89635-","C89636-","G89637-","T89638-","G89639-","G89640-","T89641-","C89642-","A89643-","A89644-","T89645-","T89646-","A89647-","C89648-","G89649-","A89650-","A89651-","T89652-","A89653-","A89654-","A89655-","G89656-","C89657-","G89658-","G89659-","A89660-","T89661-","A89662-","C89663-","T89664-","A89665-","G89666-","T89667-","A89668-","G89669-","T89670-","T89671-","T89672-","C89673-","A89674-","C89675-","A89676-","A89677-","A89678-","G89679-","A89680-","T89681-","G89682-","G89683-","C89684-","T89685-","G89686-","A89687-","A89688-","A89689-","T89690-","C89691-","A89692-","G89693-","A89694-","G89695-","C89696-","T89697-","C89698-","A89699-","C89701-","T89702-","A89703-","A89704-","G89705-","A89706-","A89707-","A89708-","T89709-","A89710-","G89711-","C89712-","G89713-","C89714-","T89715-","G89716-","A89717-","A89718-","A89719-","A89720-","T89721-","A89722-","A89723-","A89724-","G89725-","A89726-","T89727-","A89728-","A89729-","A89730-","A89731-","A89732-","C89733-","G89734-","A89735-","G89736-","G89737-","A89738-","T89739-","A89740-","T89741-","T89742-","T89743-","T89744-","C89745-","C89746-","C89747-","G89748-","G89749-","A89750-","A89751-","G89752-","A89753-","T89754-","G89755-","T89756-","A89757-","A89758-","T89759-","A89760-","A89761-","T89762-","T89763-","C89764-","C89765-","A89766-","T89767-","C89768-","T89769-","A89770-","C89771-","T89772-","A89773-","A89774-","G89775-","C89776-","C89777-","C89778-","A89779-","A89780-","A89781-","A89782-","C89783-","C89784-","A89785-","A89786-","A89787-","C89788-","G89789-","A89790-","A89791-","C89792-","C89793-","A89794-","C89795-","T89796-","A89797-","C89798-","T89799-","C89800-","C89801-","T89802-","C89803-","G89804-","T89805-","A89806-","A89807-","A89808-","C89809-","C89810-","A89811-","G89812-","C89813-","G89814-","G89815-","C89816-","T89817-","A89818-","C89819-","T89820-","A89821-","A89822-","A89823-","A89824-","G89825-","A89826-","T89827-","C89828-","A89829-","A89830-","C89831-","C89832-","A89833-","A89834-","A89835-","A89836-","A89837-","G89838-","G89839-","A89840-","T89841-","A89842-","A89843-","A89844-","G89845-","A89846-","A89847-","A89848-","A89849-","G89850-","G89851-","A89852-","G89853-","G89854-","A89855-","A89856-","G89857-","T89858-","G89859-","G89860-","A89861-","A89862-","G89863-","A89864-","A89865-","G89866-","T89867-","A89868-","G89869-","T89870-","T89871-","A89872-","T89873-","A89874-","G89875-","A89876-","G89877-","G89878-","A89879-","A89880-","T89881-","A89882-","T89883-","C89884-","A89885-","T89886-","C89887-","A89888-","A89889-","A89890-","C89891-","A89892-","A89893-","C89894-","T89895-","G89896-","A89897-","A89898-","G89899-","A89900-","A89901-","A89902-","A89903-","T89904-","T89905-","C89906-","T89907-","C89908-","C89909-","A89910-","C89911-","C89912-","T89913-","C89914-","C89915-","G89916-","T89917-","C89918-","A89919-","T89920-","C89921-","A89922-","T89923-","C89924-","T89925-","C89926-","C89927-","T89928-","G89929-","G89930-","A89931-","G89932-","T89933-","C89934-","G89935-","G89936-","C89937-","G89938-","A89939-","C89940-","A89941-","T89942-","T89943-","G89944-","T89945-","A89946-","G89947-","A89948-","A89949-","A89950-","G89951-","C89952-","G89953-","T89954-","G89955-","G89956-","C89957-","C89958-","G89959-","C89960-","T89961-","G89962-","T89963-","A89964-","G89965-","A89966-","G89967-","C89968-","T89969-","C89970-","G89971-","A89972-","T89973-","G89974-","A89975-","T89976-","A89977-","G89978-","C89979-","G89980-","A89981-","C89982-","G89983-","G89984-","G89985-","G89986-","A89987-","T89988-","G89989-","A89990-","T89991-","G89992-","A89993-","A89994-","C89995-","C89996-","T89997-","A89998-","T89999-","G90000-","G90001-","T90002-","A90003-","C90004-","A90005-","A90006-","G90007-","T90008-","T90009-","G90010-","A90011-","A90012-","G90013-","C90014-","T90015-","G90016-","G90017-","T90018-","A90019-","A90020-","A90021-","G90022-","T90023-","A90024-","A90025-","A90026-","T90027-","C90028-","A90029-","T90030-","A90031-","G90032-","T90033-","G90034-","C90035-","T90036-","A90037-","G90038-","A90039-","A90040-","G90041-","C90042-","G90043-","A90044-","T90045-","C90046-","T90047-","C90048-","T90049-","C90050-","T90051-","G90052-","A90053-","C90054-","C90055-","T90056-","A90057-","A90058-","A90059-","G90060-","G90061-","T90062-","G90063-","G90064-","C90065-","T90066-","A90067-","C90068-","C90069-","G90070-","A90071-","C90072-","A90073-","A90074-","T90075-","A90076-","T90077-","C90078-","G90079-","T90080-","T90081-","A90082-","A90083-","A90084-","G90085-","A90086-","T90087-","C90088-","T90089-","T90090-","A90091-","A90092-","G90093-","A90094-","A90095-","A90096-","A90097-","T90098-","T90099-","A90100-","T90101-","T90102-","A90103-","C90104-","T90105-","A90106-","G90107-","A90108-","A90109-","T90110-","C90111-","T90112-","C90113-","T90114-","G90115-","C90116-","A90117-","G90118-","T90119-","A90120-","T90121-","C90122-","G90123-","A90124-","C90125-","T90126-","G90127-","T90128-","T90129-","C90130-","T90131-","A90132-","G90133-","A90134-","G90135-","G90136-","A90137-","T90138-","G90139-","T90140-","T90141-","C90142-","A90143-","A90144-","G90145-","C90146-","A90147-","G90148-","C90149-","T90150-","G90151-","G90152-","T90153-","A90154-","T90155-","C90156-","T90157-","C90158-","T90159-","A90160-","G90161-","A90162-","C90163-","A90164-","A90165-","T90166-","T90167-","T90168-","A90169-","C90170-","T90171-","T90172-","C90173-","T90174-","A90175-","T90176-","G90177-","A90178-","C90179-","T90180-","A90181-","A90182-","A90183-","G90184-","C90185-","T90186-","A90187-","T90188-","T90189-","A90190-","C90191-","A90192-","A90193-","C90194-","A90195-","C90196-","T90197-","A90198-","T90199-","C90200-","T90201-","G90202-","A90203-","T90204-","C90205-","T90206-","A90207-","G90208-","T90209-","C90210-","A90211-","C90212-","C90213-","G90214-","A90215-","G90216-","G90217-","G90218-","A90219-","A90220-","A90221-","A90222-","T90223-","C90224-","T90225-","A90226-","A90227-","A90228-","G90229-","T90230-","T90231-","G90232-","T90233-","T90234-","C90235-","G90236-","T90237-","A90238-","A90239-","A90240-","A90241-","A90242-","A90243-","G90244-","T90245-","T90246-","A90247-","A90248-","A90249-","A90250-","C90251-","T90252-","T90253-","G90254-","T90255-","A90256-","A90257-","G90258-","A90259-","A90260-","G90261-","T90262-","A90263-","A90264-","A90265-","T90266-","G90267-","C90268-","G90269-","T90270-","G90271-","C90272-","A90273-","C90274-","T90275-","T90276-","T90277-","T90278-","T90279-","T90280-","A90281-","T90282-","A90283-","A90284-","A90285-","G90286-","A90287-","T90288-","G90289-","G90290-","T90291-","A90292-","A90293-","A90294-","C90295-","T90296-","G90297-","T90298-","T90299-","T90300-","A90301-","C90302-","C90303-","G90304-","A90305-","T90306-","A90307-","A90308-","T90309-","A90310-","A90311-","T90312-","T90313-","T90314-","T90315-","T90316-","T90317-","A90318-","A90319-","A90320-","T90321-","C90322-","C90323-","T90324-","G90325-","T90326-","A90327-","T90328-","C90329-","A90330-","G90331-","A90332-","C90333-","G90334-","A90335-","T90336-","A90337-","A90338-","T90339-","C90340-","C90341-","A90342-","G90343-","C90344-","G90345-","T90346-","A90347-","T90348-","G90349-","A90350-","G90351-","G90352-","T90353-","T90354-","T90355-","T90356-","G90357-","C90358-","A90359-","A90360-","C90361-","A90362-","T90363-","G90364-","T90365-","T90366-","A90367-","A90368-","A90369-","A90370-","T90371-","T90372-","C90373-","C90374-","T90375-","A90376-","C90377-","T90378-","C90379-","A90380-","T90381-","T90382-","T90383-","A90384-","A90385-","C90386-","A90387-","G90388-","A90389-","T90390-","G90391-","T90392-","A90393-","G90394-","T90395-","A90396-","G90397-","T90398-","A90399-","T90400-","A90401-","T90402-","G90403-","A90404-","A90405-","C90406-","A90407-","A90408-","A90409-","C90410-","G90411-","T90412-","G90413-","G90414-","G90415-","A90416-","A90417-","G90418-","A90419-","G90420-","G90421-","C90422-","A90423-","T90424-","T90425-","A90426-","A90427-","C90428-","T90429-","A90430-","G90431-","A90432-","T90433-","T90434-","A90435-","A90436-","T90437-","T90438-","T90439-","T90440-","T90441-","G90442-","T90443-","G90444-","G90445-","G90446-","A90447-","A90448-","G90449-","T90450-","G90451-","A90452-","T90453-","T90454-","C90455-","A90456-","A90457-","A90458-","A90459-","G90460-","G90461-","A90462-","C90463-","G90464-","T90465-","A90466-","G90467-","A90468-","C90469-","A90470-","A90471-","T90472-","A90473-","C90474-","T90475-","T90476-","T90477-","T90478-","A90479-","C90480-","G90481-","G90482-","A90483-","A90484-","A90485-","A90486-","A90487-","T90488-","G90489-","C90490-","A90491-","T90492-","A90493-","T90494-","A90495-","C90496-","A90497-","G90498-","A90499-","A90500-","T90501-","C90502-","G90503-","C90504-","A90505-","A90506-","T90507-","G90508-","C90509-","T90510-","A90511-","A90512-","A90513-","A90514-","G90515-","A90516-","G90517-","A90518-","T90519-","C90520-","G90521-","T90522-","A90523-","T90524-","T90525-","T90526-","T90527-","T90528-","G90529-","T90530-","T90531-","A90532-","G90533-","A90534-","G90535-","T90536-","A90537-","T90538-","A90539-","T90540-","A90541-","A90542-","C90543-","G90544-","T90545-","T90546-","A90547-","T90548-","G90549-","A90550-","A90551-","A90552-","C90553-","G90554-","A90555-","A90556-","T90557-","T90558-","A90559-","A90560-","T90561-","T90562-","G90563-","T90564-","T90565-","T90566-","T90567-","A90568-","T90569-","A90570-","A90571-","A90572-","C90573-","A90574-","A90575-","A90576-","A90577-","A90578-","T90579-","A90580-","T90581-","A90582-","A90583-","A90584-","G90585-","A90586-","A90587-","A90588-","T90589-","C90590-","G90591-","T172130-","T172131-","C172132-","C172133-","T173843-","A173844-","G173845-","T173846-","A173847-"],"OPG080":["S84-","N85-"]},"labels":{"aa":"OPG080: S84-, N85-"}}}]}]}]}]},{"name":"NODE_0000132","node_attrs":{"div":1,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C182950T"],"OPG210":["S532L"]},"labels":{"aa":"OPG210: S532L","clade":"B.1.12"}},"children":[{"name":"NODE_0000133","node_attrs":{"div":3,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G1302A","C57550T","G78328A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C195908T"],"OPG001":["L92F"],"OPG001_dup":["L92F"]},"labels":{"aa":"OPG001: L92F; OPG001_dup: L92F"}},"children":[{"name":"OP415207","node_attrs":{"div":3,"accession":"OP415207","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_BhVKjm_9000233"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415207/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OP415206","node_attrs":{"div":3,"accession":"OP415206","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_BhVKjm_9000232"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415206/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000134","node_attrs":{"div":2,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G111084A"]}},"children":[{"name":"ON880548","node_attrs":{"div":2,"accession":"ON880548","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3448/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880548/2022-06-03"},"date":{"value":"2022-06-03"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000135","node_attrs":{"div":4,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G98233A","G98455A","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG117":["D729N"],"OPG118":["G4K"]},"labels":{"aa":"OPG117: D729N; OPG118: G4K"}},"children":[{"name":"ON880413","node_attrs":{"div":5,"accession":"ON880413","author":{"author":"Coletti,T.M.,Ghilardi,F.,khan,M.J.,Claro,I.M.,Valenca,I.N.,Faria,N.R.,Sabino,E.C.","value":"Coletti,T.M.,Ghilardi,F.,khan,M.J.,Claro,I.M.,Valenca,I.N.,Faria,N.R.,Sabino,E.C."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/BR0002/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Imperial College London, School of Public Health"},"strain_display":{"value":"Brazil/ON880413/2022-06-14"},"date":{"value":"2022-06-14"},"country":{"value":"Brazil"}},"branch_attrs":{"mutations":{"nuc":["C76334T","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A173314-","T173315-","A173316-","T173317-","-179189A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG097":["R181K"]},"labels":{"aa":"OPG097: R181K"}}},{"name":"NODE_0000136","node_attrs":{"div":5,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G98456A"]}},"children":[{"name":"OP270022","node_attrs":{"div":8,"accession":"OP270022","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3972/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP270022/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","G3361A","C152970T","-179158A","-179160A","-179161T","-179162A","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G181349A","C193849T"],"OPG003":["S416L"],"OPG003_dup":["S416L"]},"labels":{"aa":"OPG003: S416L; OPG003_dup: S416L"}}},{"name":"OP378701","node_attrs":{"div":6,"accession":"OP378701","author":{"author":"Gigante,C.M.,Hughes,S.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y.","value":"Gigante,C.M.,Hughes,S.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Baumgartner,J.,Li,Y."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_NY0028"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP378701/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T4775-","A4776-","A4777-","C4778-","T4779-","A4780-","A4781-","C4782-","T4783-","T4784-","A4785-","T4786-","G4787-","A4788-","C4789-","T4790-","T4791-","A4792-","A4793-","C4794-","T4795-","A4796-","A4797-","C4798-","T4799-","T4800-","A4801-","T4802-","G4803-","A4804-","C4805-","T4806-","C40966T","C179154-","A179155-","T179156-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"],"OPG060":["D73N"]},"labels":{"aa":"OPG060: D73N"}}},{"name":"OR209309","node_attrs":{"div":8,"accession":"OR209309","author":{"author":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_TN0019"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OR209309/2022-12-XX"},"date":{"value":"2022-12-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C93601T","C94418T","T133101-","T133102-","C136029T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["A624V"],"OPG114":["E84K"]},"labels":{"aa":"OPG113: A624V; OPG114: E84K"}}},{"name":"NODE_0000137","node_attrs":{"div":6,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C24231T"]}},"children":[{"name":"OP390179","node_attrs":{"div":6,"accession":"OP390179","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"BOL-UNIMOL-MPX-293015-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"strain_display":{"value":"Colombia/OP390179/2022-08-24"},"date":{"value":"2022-08-24"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OR264365","node_attrs":{"div":7,"accession":"OR264365","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"12_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264365/2022-07-18"},"date":{"value":"2022-07-18"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["G23457A"],"OPG039":["S221F"]},"labels":{"aa":"OPG039: S221F"}}}]},{"name":"NODE_0000138","node_attrs":{"div":6,"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G153910A"],"OPG180":["E407K"]},"labels":{"aa":"OPG180: E407K"}},"children":[{"name":"OQ918701","node_attrs":{"div":11,"accession":"OQ918701","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00490/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ918701/2023-02-10"},"date":{"value":"2023-02-10"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C21910T","G28483A","G39552A","A57421-","C57422-","A57423-","A57424-","A57425-","A57426-","A57427-","G57428-","G57429-","A57430-","C57431-","A57432-","T57433-","G57434-","T57435-","A57436-","A57437-","A57438-","C57439-","T57440-","T57441-","G132490A","C150443T","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG037":["R175K"],"OPG057":["S215F"],"OPG075":["K20-","F21-","T22-","C23-","P24-","F25-","C26-"],"OPG176":["T212I"]},"labels":{"aa":"OPG037: R175K; OPG057: S215F; OPG075: K20-, F21-, T22-, C23-, P24-, F25-, C26-; OPG176: T212I"}}},{"name":"OR759180","node_attrs":{"div":10,"accession":"OR759180","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.12"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL092/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759180/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["T606-","C16209T","C24208T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","G182088A","G182189A","A196614-"],"OPG027":["E57K"],"OPG210":["E245K"]},"labels":{"aa":"OPG027: E57K; OPG210: E245K"}}}]}]}]}]}]},{"name":"NODE_0000139","node_attrs":{"div":2,"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G12169A","G44960A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]},"labels":{"clade":"B.1.17"}},"children":[{"name":"OP442552","node_attrs":{"div":2,"accession":"OP442552","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00085/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP442552/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G771-","T772-","G773-","A196789-","A196790-","T196791-"]}}},{"name":"OP890564","node_attrs":{"div":3,"accession":"OP890564","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00336/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP890564/2022-11-09"},"date":{"value":"2022-11-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A39482T"],"OPG057":["H238Q"]},"labels":{"aa":"OPG057: H238Q"}}},{"name":"OP890557","node_attrs":{"div":3,"accession":"OP890557","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00329/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP890557/2022-11-09"},"date":{"value":"2022-11-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","A13238C","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000140","node_attrs":{"div":3,"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A39081T","A196780-","A196781-","T196782-"],"OPG057":["I372N"]},"labels":{"aa":"OPG057: I372N"}},"children":[{"name":"OP890570","node_attrs":{"div":4,"accession":"OP890570","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00313/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP890570/2022-11-09"},"date":{"value":"2022-11-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G178111A","C196672-","T196673-","G196674-"]}}},{"name":"OP890553","node_attrs":{"div":3,"accession":"OP890553","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00325/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP890553/2022-11-09"},"date":{"value":"2022-11-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000141","node_attrs":{"div":3,"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G140635A"],"OPG160":["S147L"]},"labels":{"aa":"OPG160: S147L"}},"children":[{"name":"OP890567","node_attrs":{"div":5,"accession":"OP890567","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00310/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP890567/2022-11-09"},"date":{"value":"2022-11-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C39334G","G164476A"],"OPG057":["A288P"],"OPG189":["E382K"]},"labels":{"aa":"OPG057: A288P; OPG189: E382K"}}},{"name":"OP890569","node_attrs":{"div":4,"accession":"OP890569","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00312/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP890569/2022-11-09"},"date":{"value":"2022-11-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A763-","A764-","T765-","G39312T","-179145T","T179244-","T196678-","C196679-","T196680-"],"OPG057":["A295E"]},"labels":{"aa":"OPG057: A295E"}}}]},{"name":"NODE_0000142","node_attrs":{"div":3,"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A39395-","T39396-","T39397-","C85931T"],"OPG057":["N267-"]},"labels":{"aa":"OPG057: N267-"}},"children":[{"name":"OQ330999","node_attrs":{"div":4,"accession":"OQ330999","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00391/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ330999/2022-12-19"},"date":{"value":"2022-12-19"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C174129T"]}}},{"name":"OQ503816","node_attrs":{"div":3,"accession":"OQ503816","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00423/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ503816/2022-12-02"},"date":{"value":"2022-12-02"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000143","node_attrs":{"div":5,"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G71249A","G182189A"],"OPG090":["R24Q"]},"labels":{"aa":"OPG090: R24Q"}},"children":[{"name":"OQ547884","node_attrs":{"div":6,"accession":"OQ547884","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000176/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDPH, VRDL"},"strain_display":{"value":"USA/OQ547884/2023-01-06"},"date":{"value":"2023-01-06"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T760-","T761-","T762-","G79741A"],"OPG102":["M219I"]},"labels":{"aa":"OPG102: M219I"}}},{"name":"OQ644784","node_attrs":{"div":7,"accession":"OQ644784","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.17"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00478/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ644784/2023-01-08"},"date":{"value":"2023-01-08"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A11160G","T133529G"],"OPG023":["F581L"]},"labels":{"aa":"OPG023: F581L"}}}]}]}]},{"name":"NODE_0000144","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C132698T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}},"children":[{"name":"OP555508","node_attrs":{"div":4,"accession":"OP555508","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0416/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555508/2022-07-26"},"date":{"value":"2022-07-26"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G40375A","C92352T","C120425T"],"OPG137":["S275L"]},"labels":{"aa":"OPG137: S275L"}}},{"name":"OP555512","node_attrs":{"div":1,"accession":"OP555512","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0424/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555512/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-607T"]}}},{"name":"OP555662","node_attrs":{"div":3,"accession":"OP555662","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0595/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555662/2022-09-16"},"date":{"value":"2022-09-16"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T109045C","T122837G"],"OPG128":["Y4C"],"OPG143":["N160T"]},"labels":{"aa":"OPG128: Y4C; OPG143: N160T"}}},{"name":"NODE_0000145","node_attrs":{"div":7,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C18441T","G22415A","G70002A","G143951A","C148604T","G154188A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C196745-","C196746-","A196747-"],"OPG031":["E130K"],"OPG089":["R46K"],"OPG165":["D146N"],"OPG174":["M264I"]},"labels":{"aa":"OPG031: E130K; OPG089: R46K; OPG165: D146N; OPG174: M264I"}},"children":[{"name":"OR643700","node_attrs":{"div":10,"accession":"OR643700","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00558/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643700/2023-08-24"},"date":{"value":"2023-08-24"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C96773T","A166129G","G168741A"],"OPG117":["S242L"],"OPG195":["R171K"]},"labels":{"aa":"OPG117: S242L; OPG195: R171K"}}},{"name":"OR499996","node_attrs":{"div":9,"accession":"OR499996","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00540/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499996/2023-07-01"},"date":{"value":"2023-07-01"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G30433A","C57102T","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR499994","node_attrs":{"div":7,"accession":"OR499994","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00538/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499994/2023-07-21"},"date":{"value":"2023-07-21"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499993","node_attrs":{"div":7,"accession":"OR499993","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00537/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499993/2023-07-06"},"date":{"value":"2023-07-06"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000146","node_attrs":{"div":9,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G70425A","C137966T"],"OPG089":["G187E"],"OPG154":["E29K"]},"labels":{"aa":"OPG089: G187E; OPG154: E29K"}},"children":[{"name":"OR643711","node_attrs":{"div":9,"accession":"OR643711","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00555/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643711/2023-08-02"},"date":{"value":"2023-08-02"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR643708","node_attrs":{"div":9,"accession":"OR643708","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00553/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643708/2023-07-28"},"date":{"value":"2023-07-28"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000147","node_attrs":{"div":8,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C14823A"],"OPG025":["D149Y"]},"labels":{"aa":"OPG025: D149Y"}},"children":[{"name":"OR643701","node_attrs":{"div":8,"accession":"OR643701","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00559/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643701/2023-08-07"},"date":{"value":"2023-08-07"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499982","node_attrs":{"div":8,"accession":"OR499982","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00525/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499982/2023-06-14"},"date":{"value":"2023-06-14"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000148","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C148268T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"ON755039","node_attrs":{"div":1,"accession":"ON755039","author":{"author":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O.","value":"Jarjaval,F.,Nolent,F.,Criqui,A.,Chapus,C.,Lamer,O.,Ferraris,O.,Gorge,O."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_IRBA22-11"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IRBA, D.DNRBC/D.2MI/U.BACT"},"strain_display":{"value":"France/ON755039/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A173314-","T173315-","A173316-","T173317-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}}},{"name":"OR035703","node_attrs":{"div":2,"accession":"OR035703","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_97"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035703/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C162521T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T"],"OPG188":["S309L"]},"labels":{"aa":"OPG188: S309L"}}},{"name":"OR264451","node_attrs":{"div":4,"accession":"OR264451","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"65_D"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264451/2022-08-25"},"date":{"value":"2022-08-25"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["T96531G","G158414A","G159694A","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG185":["V260I"]},"labels":{"aa":"OPG185: V260I"}}},{"name":"NODE_0000149","node_attrs":{"div":2,"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G9963A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T"],"OPG021":["R126K"]},"labels":{"aa":"OPG021: R126K","clade":"B.1.19"}},"children":[{"name":"OP270026","node_attrs":{"div":2,"accession":"OP270026","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Antonation,K.,Griffiths,E.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-4017/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP270026/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-196615A","-196616A","-196617A"]}}},{"name":"OP382481","node_attrs":{"div":4,"accession":"OP382481","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00004"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382481/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["G115549A","T133102-","C163653T","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"],"OPG133":["P50S"]},"labels":{"aa":"OPG133: P50S"}}},{"name":"OP838893","node_attrs":{"div":2,"accession":"OP838893","author":{"author":"Viscardi,M.,Cozzolino,L.,De Martinis,C.,Cardillo,L.,Fusco,G.","value":"Viscardi,M.,Cozzolino,L.,De Martinis,C.,Cardillo,L.,Fusco,G."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ID6821"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Istituto Zooprofilattico Sperimentale del Mezzogiorno, Hanimal Health"},"strain_display":{"value":"Italy/OP838893/2022-06-21"},"date":{"value":"2022-06-21"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["T4736-","A4737-","T4738-","G4739-","A4740-","C4741-","T4742-","T4743-","A4744-","A4745-","C4746-","T4747-","T133100-","T133101-","T133102-","C133103-","G133104-","A133105-","A133106-","T133107-","T133108-","C133109-","A133110-","C133111-","G133112-","A140134-","A140135-","C140136-","A140137-","A140138-","T140139-","T140140-","A140141-","T140142-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A157678-","A157679-","A157680-","A157681-","T157682-","T157683-","T157684-","T157685-","A157686-","A157687-","G157688-","C157689-","G157690-","A157691-","T157692-","G157693-","A157694-","T157695-","A157696-","T163214-","C163215-","T163216-","T163217-","A163218-","T163219-","A163220-","T163221-","A163417-","A163418-","T163419-","T163420-","C163421-","T163422-","T163423-","C163424-","C163425-","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","G174537-","A174538-","T174539-","G174540-","A174541-","A174542-","A180482-","T180483-","T180484-","A180485-","A180486-","A180487-","A180488-","A180489-","A181114-","T181115-","T181116-","C181117-","C181118-","T181119-","T181120-","A181121-","T181122-","T192478-","A192479-","G192480-","T192481-","T192482-","A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-"],"OPG159":["N124-","Y125-","N126-"],"OPG189":["N29-","S30-","S31-"]},"labels":{"aa":"OPG159: N124-, Y125-, N126-; OPG189: N29-, S30-, S31-"}}},{"name":"OR035726","node_attrs":{"div":4,"accession":"OR035726","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_120"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035726/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C22739T","G133104A","G133231A","T137560-","G164487A"],"OPG038":["E141K"]},"labels":{"aa":"OPG038: E141K"}}},{"name":"NODE_0000150","node_attrs":{"div":3,"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G150003A"]}},"children":[{"name":"OP382486","node_attrs":{"div":6,"accession":"OP382486","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00009"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382486/2022-07-07"},"date":{"value":"2022-07-07"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["C38483T","C164272T","G175971A","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"],"OPG189":["R314C"],"OPG205":["E106K"]},"labels":{"aa":"OPG189: R314C; OPG205: E106K"}}},{"name":"OP555643","node_attrs":{"div":6,"accession":"OP555643","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0572/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555643/2022-09-05"},"date":{"value":"2022-09-05"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-607T","C55057T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A169944T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C185326T","-196615A"],"OPG073":["E29K"],"OPG197":["E92V"],"OPG210":["S1324L"]},"labels":{"aa":"OPG073: E29K; OPG197: E92V; OPG210: S1324L"}}},{"name":"OQ172215","node_attrs":{"div":7,"accession":"OQ172215","author":{"author":"Zeggagh,J.,Ferraris,O.,Salmona,M.,Tarantola,A.,Molina,J.M.,Delaugerre,C.","value":"Zeggagh,J.,Ferraris,O.,Salmona,M.,Tarantola,A.,Molina,J.M.,Delaugerre,C."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-1047"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Hopital Saint Louis, Paris"},"strain_display":{"value":"France/OQ172215/2022-06-07"},"date":{"value":"2022-06-07"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["A2591G","A31053G","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133171-","C133172-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T133639-","A150635-","A152676-","T152686-","T155897A","C173533A","A179077T","A179079T","A179081T","C179082T","A179083T","A179086T","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T194619C","T194627G"],"OPG002":["F54S"],"OPG002_dup":["F54S","C57G"],"OPG047":["C48R"]},"labels":{"aa":"OPG002: F54S; OPG002_dup: F54S, C57G; OPG047: C48R"}}},{"name":"NODE_0000151","node_attrs":{"div":4,"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C74417T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A196614-"],"OPG094":["S213L"]},"labels":{"aa":"OPG094: S213L"}},"children":[{"name":"OP536781","node_attrs":{"div":5,"accession":"OP536781","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000405"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536781/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C62868T"]}}},{"name":"NODE_0000152","node_attrs":{"div":5,"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C22179T"]}},"children":[{"name":"OP536803","node_attrs":{"div":5,"accession":"OP536803","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000431"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536803/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["G190782-","A190783-","A190784-","A190785-"],"OPG016":["E125-","I126-"]},"labels":{"aa":"OPG016: E125-, I126-"}}},{"name":"OP536782","node_attrs":{"div":5,"accession":"OP536782","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.19"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000406"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536782/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-606T","-196614A"]}}}]}]}]}]}]},{"name":"NODE_0000153","node_attrs":{"div":1,"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G5595A","C191615T"],"OPG015":["Q188*"],"OPG015_dup":["Q188*"]},"labels":{"aa":"OPG015: Q188*; OPG015_dup: Q188*","clade":"B.1.8"}},"children":[{"name":"OP215224","node_attrs":{"div":1,"accession":"OP215224","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI235"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP215224/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"NODE_0000154","node_attrs":{"div":2,"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G902A","G161296A","C196308T"],"OPG001_dup":["S225L"]},"labels":{"aa":"OPG001_dup: S225L"}},"children":[{"name":"OP331337","node_attrs":{"div":2,"accession":"OP331337","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000183"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP331337/2022-06-29"},"date":{"value":"2022-06-29"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG001":["S225L"]},"labels":{"aa":"OPG001: S225L"}}},{"name":"OP484679","node_attrs":{"div":2,"accession":"OP484679","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI358"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP484679/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG001":["S225L"]},"labels":{"aa":"OPG001: S225L"}}},{"name":"OP626130","node_attrs":{"div":3,"accession":"OP626130","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI492"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP626130/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A902G","C24929T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T196308C"],"OPG001_dup":["L225S"],"OPG040":["D184N"]},"labels":{"aa":"OPG001_dup: L225S; OPG040: D184N"}}},{"name":"OP863250","node_attrs":{"div":5,"accession":"OP863250","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI600"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP863250/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A902G","G89716A","G128858A","-179188T","-179189A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","G181052-","C186220T"],"OPG110":["E29K"],"OPG209":["G179-"],"OPG210":["A1622V"]},"labels":{"aa":"OPG110: E29K; OPG209: G179-; OPG210: A1622V"}}},{"name":"OR035714","node_attrs":{"div":5,"accession":"OR035714","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_108"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035714/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["A902G","C80545T","G102614A","C170573T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG103":["S182L"],"OPG122":["V63I"],"OPG198":["S179L"]},"labels":{"aa":"OPG103: S182L; OPG122: V63I; OPG198: S179L"}}},{"name":"OR030928","node_attrs":{"div":3,"accession":"OR030928","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_17"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR030928/2022-07-19"},"date":{"value":"2022-07-19"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C68981T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG001":["S225L"],"OPG087":["S42L"]},"labels":{"aa":"OPG001: S225L; OPG087: S42L"}}}]},{"name":"NODE_0000155","node_attrs":{"div":3,"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G78034A","C80111T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG099":["D124N"]},"labels":{"aa":"OPG099: D124N"}},"children":[{"name":"ON720849","node_attrs":{"div":4,"accession":"ON720849","author":{"author":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/Spain/MD-HGUGM-6532064/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Microbial Genomics, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"},"strain_display":{"value":"Spain/ON720849/2022-05-27"},"date":{"value":"2022-05-27"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["A327-","T604-","T605-","T606-","A1697-","A8055-","A9529-","C11749-","T15127-","T16099-","A19360-","A21081-","A27114-","A28529-","A28530-","A28602-","T32194-","A33199-","T34046-","T35571-","T37982-","T39131-","T39866-","T41744-","A43500-","T43509-","T46648-","A55124-","T56040-","A57277-","A58650-","A62041-","T64752-","A64935-","G69145-","A69744-","T76084-","T76085-","A76890-","A79181-","T79229-","A79460-","A79787-","T80849-","T88095-","T88836-","A89106-","A91705-","T94647-","T94795-","A98080-","T103367-","T105360-","T108715-","A110978-","T114518-","T114755-","A116014-","T116963-","T121121-","C122649T","A123995-","A124727-","A127250-","A127754-","A128933-","A132023-","A132024-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133639-","T137886-","A138474-","A142466-","A144230-","A148000-","A148351-","T150539-","A150635-","A151986-","A152676-","T152686-","A153424-","A154129-","T155424-","A157997-","T163597-","T168120-","A168962-","A170728-","T170904-","T172087-","T172667-","T178048-","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","A179950-","G181052-","A181253-","A182646-","T187080-","A190935-","T195519-","A196593-","A196611-","A196612-","A196613-","A196614-","T197183-"],"OPG016":["T176-"],"OPG044":["K147-"],"OPG084":["F11-"],"OPG087":["G97-"],"OPG102":["K33-","K126-","K235-"],"OPG115":["S46-"],"OPG117":["K678-"],"OPG134":["N89-"],"OPG143":["D223N"],"OPG145":["M17-"],"OPG149":["K19-"],"OPG151":["N4-","K1034-"],"OPG163":["N89-"],"OPG165":["M239-"],"OPG172":["I192-"],"OPG178":["M160-"],"OPG180":["N245-"],"OPG189":["F89-"],"OPG193":["F263-"],"OPG198":["K231-"],"OPG208":["N229-"],"OPG209":["G179-"],"OPG210":["K431-"]},"labels":{"aa":"OPG016: T176-; OPG044: K147-; OPG084: F11-; OPG087: G97-; OPG102: K33-, K126-, K235-; OPG115: S46-; OPG117: K678-; OPG134: N89-; OPG143: D223N; OPG145: M17-; OPG149: K19-; OPG151: N4-, K1034-; OPG163: N89-; OPG165: M239-; OPG172: I192-; OPG178: M160-; OPG180: N245-; OPG189: F89-; OPG193: F263-; OPG198: K231-; OPG208: N229-; OPG209: G179-; OPG210: K431-"}}},{"name":"ON622718","node_attrs":{"div":4,"accession":"ON622718","author":{"author":"Martinez-Puchol,S.,Coello,A.,Bordoy,A.E.,Soler,L.,Panisello,D.,Gonzalez-Gomez,S.,Clara,G.,Paris de Leon,A.,Not,A.,Hernandez,A.,Bofill-Mas,S.,Saludes,V.,Blanco,I.,Martro,E.,Cardona,P.-J.","value":"Martinez-Puchol,S.,Coello,A.,Bordoy,A.E.,Soler,L.,Panisello,D.,Gonzalez-Gomez,S.,Clara,G.,Paris de Leon,A.,Not,A.,Hernandez,A.,Bofill-Mas,S.,Saludes,V.,Blanco,I.,Martro,E.,Cardona,P.-J."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/ES0001/HUGTiP/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Microbiology, Hospital Universitari Germans Trias i Pujol, Spain"},"strain_display":{"value":"Spain/ON622718/2022-05-20"},"date":{"value":"2022-05-20"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","C14113-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T139150C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","A179283-","C179284-","T179285-","A179286-","A179287-","T179288-","C179289-","T179290-","T179291-","A179292-","A179293-","A179294-","A179295-","C179296-","A179297-","T179298-","A179299-","C179300-","G179301-","G179302-","A179303-","T179304-","G179305-","A179306-","A179307-","A179308-","A179309-","T179310-","G179311-","T179312-","T179313-","T179314-","T179315-","G179316-","A179317-","T179318-","T179319-","T179320-","C179321-","T179322-","C179323-","C179324-","A179325-","G179326-","T179327-","T179328-","T179329-","C179330-","C179331-","A179332-","T179333-","T179334-","T179335-","T179336-","A179337-","T179338-","C179339-","T179340-","A179341-","C179342-","T179343-","T179344-","T179345-","A179346-","T179347-","C179348-","T179349-","A179350-","T179351-","T179352-","C179353-","T179354-","G179355-","A179356-","A179357-","T179358-","C179359-","A179360-","T179361-","-196615A","-196616A"],"OPG156":["Q87R"]},"labels":{"aa":"OPG156: Q87R"}}},{"name":"NODE_0000156","node_attrs":{"div":5,"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G22643A","G63811A","-179194A","-179195T","-179196A","-179197T","-179198A"],"OPG038":["H173Y"]},"labels":{"aa":"OPG038: H173Y"}},"children":[{"name":"OP303778","node_attrs":{"div":5,"accession":"OP303778","author":{"author":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y.","value":"Gigante,C.M.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Mendoza,R.,Li,Y."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_FL0015"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP303778/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP415254","node_attrs":{"div":7,"accession":"OP415254","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_imBNaw_9000300"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415254/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T119985C","A179194-","T179195-","A179196-","T179197-","A179198-","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","G189258A"]}}},{"name":"OP477454","node_attrs":{"div":5,"accession":"OP477454","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-23267-O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP477454/2022-08-23"},"date":{"value":"2022-08-23"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP477452","node_attrs":{"div":5,"accession":"OP477452","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-23265-C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP477452/2022-08-23"},"date":{"value":"2022-08-23"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP450995","node_attrs":{"div":5,"accession":"OP450995","author":{"author":"Gigante,C.M.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y.","value":"Gigante,C.M.,Thomas,L.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Dunn,J.,Li,Y."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_TN0001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP450995/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179199C","-179200A","-179201T","-179202T","A182310-","T182311-","T182312-","G182313-","G182314-","T182315-","G182316-","T182317-","A182318-","A182319-","A182320-","A182321-","G182322-","A182323-","T182324-","G182325-","A182326-","T182327-","G182328-","A182329-","A182330-","A182331-"],"OPG210":["I319-","G320-","V321-","K322-","D323-","D324-","E325-","N326-"]},"labels":{"aa":"OPG210: I319-, G320-, V321-, K322-, D323-, D324-, E325-, N326-"}}},{"name":"OP642374","node_attrs":{"div":6,"accession":"OP642374","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-24722-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642374/2022-09-08"},"date":{"value":"2022-09-08"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G168759A","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG195":["R177K"]},"labels":{"aa":"OPG195: R177K"}}},{"name":"OQ320513","node_attrs":{"div":9,"accession":"OQ320513","author":{"author":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y.","value":"Gigante,C.,Lee,P.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Burroughs,M.S.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Stanek,D.,Li,Y."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_FL0009"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ320513/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G4038A","A39081T","C67289T","G73790A","T133102-","A173284-","T173285-","A173286-","T173287-","A173288-","T173289-","A173290-","T173291-","A173292-","T173293-","A173294-","T173295-","A173296-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","C193172T"],"OPG057":["I372N"],"OPG085":["E415K"],"OPG094":["G4E"]},"labels":{"aa":"OPG057: I372N; OPG085: E415K; OPG094: G4E"}}},{"name":"OR759149","node_attrs":{"div":9,"accession":"OR759149","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.8"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL055/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759149/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C8555T","G95862A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168089T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G181674A","-196615A"],"OPG116":["A168T"],"OPG210":["E107K"]},"labels":{"aa":"OPG116: A168T; OPG210: E107K"}}}]}]}]},{"name":"NODE_0000157","node_attrs":{"div":4,"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C18133T","G67611A","G130231A","G159277A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG185":["E121K"]},"labels":{"aa":"OPG185: E121K","clade":"B.1.11"}},"children":[{"name":"OP169336","node_attrs":{"div":4,"accession":"OP169336","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-070499/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP169336/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A"]}}},{"name":"OP440582","node_attrs":{"div":5,"accession":"OP440582","author":{"author":"Hemarajata,P.,Green,N.M.","value":"Hemarajata,P.,Green,N.M."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPX/Human/USA/CA-LACPHL-MA00009/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP440582/2022-07-22"},"date":{"value":"2022-07-22"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C31162T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP390178","node_attrs":{"div":4,"accession":"OP390178","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MAG-UNIMOL-MPX-292982-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"strain_display":{"value":"Colombia/OP390178/2022-08-20"},"date":{"value":"2022-08-20"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP378706","node_attrs":{"div":5,"accession":"OP378706","author":{"author":"Gigante,C.M.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.M.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_IL0053"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP378706/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C161002T","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP536709","node_attrs":{"div":5,"accession":"OP536709","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-USA-IL-IDPH-048"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"strain_display":{"value":"USA/OP536709/2022-06-23"},"date":{"value":"2022-06-23"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","T48717A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A","-196616A","-196617A"],"OPG068":["L173I"]},"labels":{"aa":"OPG068: L173I"}}},{"name":"OP536703","node_attrs":{"div":4,"accession":"OP536703","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-USA-IL-IDPH-042"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"strain_display":{"value":"USA/OP536703/2022-06-23"},"date":{"value":"2022-06-23"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G173318A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A","-196616A","-196617A"]}}},{"name":"OP603012","node_attrs":{"div":4,"accession":"OP603012","author":{"author":"Gigante,C.M.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y.","value":"Gigante,C.M.,Ventura,J.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Seabolt,M.H.,Weigand,M.R.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Nash,J.,Li,Y."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_CA0034"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP603012/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","-196615A"]}}},{"name":"OP819960","node_attrs":{"div":7,"accession":"OP819960","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"SAN_INS_MPX_0973_L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP819960/2022-10-17"},"date":{"value":"2022-10-17"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A19748-","G19749-","G19750-","C19751-","G19752-","T19753-","G27840A","C64404T","C96810T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG034":["T87-","P88-"],"OPG043":["S39F"],"OPG083":["D105N"]},"labels":{"aa":"OPG034: T87-, P88-; OPG043: S39F; OPG083: D105N"}}},{"name":"OP642421","node_attrs":{"div":5,"accession":"OP642421","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-25510E"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642421/2022-09-03"},"date":{"value":"2022-09-03"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C90842T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG111":["S193F"]},"labels":{"aa":"OPG111: S193F"}}},{"name":"OQ148469","node_attrs":{"div":7,"accession":"OQ148469","author":{"author":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Lopez,P.A.,Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LBMB-UTP_MP-013_VAC"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"strain_display":{"value":"Colombia/OQ148469/2022-11-11"},"date":{"value":"2022-11-11"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C29040T","G128544A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","G182189A"],"OPG045":["D75N"],"OPG150":["D256N"]},"labels":{"aa":"OPG045: D75N; OPG150: D256N"}}},{"name":"OP959063","node_attrs":{"div":6,"accession":"OP959063","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"BOL-UNIMOL-MPX-293633-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"strain_display":{"value":"Colombia/OP959063/2022-11-15"},"date":{"value":"2022-11-15"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C132590T","G139081A"],"OPG156":["S110F"]},"labels":{"aa":"OPG156: S110F"}}},{"name":"OP959062","node_attrs":{"div":4,"accession":"OP959062","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"BOL-UNIMOL-MPX-293614-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"strain_display":{"value":"Colombia/OP959062/2022-11-11"},"date":{"value":"2022-11-11"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{}}},{"name":"OQ320458","node_attrs":{"div":8,"accession":"OQ320458","author":{"author":"Gigante,C.,Cleavinger,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Burroughs,M.R.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Sinn,M.,Li,Y.","value":"Gigante,C.,Cleavinger,K.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Burroughs,M.R.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Sinn,M.,Li,Y."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_MO0002"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ320458/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T606-","G19458A","G149818A","T167929A","-179194A","-179195T","-179196A","-179197T","-179198A","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C185455T","A196614-"],"OPG034":["S183L"],"OPG176":["D4N"],"OPG193":["I199N"],"OPG210":["S1367L"]},"labels":{"aa":"OPG034: S183L; OPG176: D4N; OPG193: I199N; OPG210: S1367L"}}},{"name":"OR035719","node_attrs":{"div":7,"accession":"OR035719","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_113"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035719/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","C142797T","C167995T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G189258A"],"OPG164":["S7L"],"OPG193":["S221F"]},"labels":{"aa":"OPG164: S7L; OPG193: S221F"}}},{"name":"OQ957072","node_attrs":{"div":7,"accession":"OQ957072","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-3668E"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ957072/2023-02-16"},"date":{"value":"2023-02-16"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C35308T","G71777A","C120979T"],"OPG054":["R230H"],"OPG138":["D52N"]},"labels":{"aa":"OPG054: R230H; OPG138: D52N"}}},{"name":"NODE_0000158","node_attrs":{"div":5,"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G17023A","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG029":["S16F"]},"labels":{"aa":"OPG029: S16F"}},"children":[{"name":"OQ696093","node_attrs":{"div":8,"accession":"OQ696093","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-29778O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ696093/2022-11-03"},"date":{"value":"2022-11-03"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C35308T","G102395A","G148319A"],"OPG054":["R230H"]},"labels":{"aa":"OPG054: R230H"}}},{"name":"NODE_0000159","node_attrs":{"div":8,"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G74462A","C80742T","G113382A"],"OPG094":["R228K"],"OPG104":["R93Q"]},"labels":{"aa":"OPG094: R228K; OPG104: R93Q"}},"children":[{"name":"OQ696101","node_attrs":{"div":8,"accession":"OQ696101","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-30628C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ696101/2022-11-11"},"date":{"value":"2022-11-11"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["-179265C","-179266A","-179267T","-179268G","-179269G","-179270A","-179271T","-179272A","-179273T","-179274C","-179275T","-179276T","-179277T","-179278A","-179279A","-179280A","-179281G","-179282A"]}}},{"name":"OQ696092","node_attrs":{"div":8,"accession":"OQ696092","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.11"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-29706O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ696092/2022-11-03"},"date":{"value":"2022-11-03"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["T196988-","A196989-","A196990-"]}}}]}]}]},{"name":"NODE_0000160","node_attrs":{"div":1,"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G111029A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]},"labels":{"clade":"B.1.6"}},"children":[{"name":"OP320554","node_attrs":{"div":3,"accession":"OP320554","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS-016"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP320554/2022-07-09"},"date":{"value":"2022-07-09"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{"nuc":["G25098A","A34289G"]}}},{"name":"OP320548","node_attrs":{"div":1,"accession":"OP320548","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS008"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP320548/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{}}},{"name":"OP320552","node_attrs":{"div":2,"accession":"OP320552","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS-012"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP320552/2022-07-06"},"date":{"value":"2022-07-06"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{"nuc":["C96110T"],"OPG117":["S21L"]},"labels":{"aa":"OPG117: S21L"}}},{"name":"OP320553","node_attrs":{"div":1,"accession":"OP320553","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS-013"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP320553/2022-07-08"},"date":{"value":"2022-07-08"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{}}},{"name":"OP320549","node_attrs":{"div":1,"accession":"OP320549","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS-010"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP320549/2022-07-02"},"date":{"value":"2022-07-02"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{}}},{"name":"OP431402","node_attrs":{"div":2,"accession":"OP431402","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-22752-O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP431402/2022-08-18"},"date":{"value":"2022-08-18"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G15814A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP642385","node_attrs":{"div":1,"accession":"OP642385","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-24910-O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642385/2022-09-09"},"date":{"value":"2022-09-09"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-"]}}},{"name":"OQ261706","node_attrs":{"div":1,"accession":"OQ261706","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-28353C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ261706/2022-10-14"},"date":{"value":"2022-10-14"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","T196852-","G196853-","T196854-"]}}},{"name":"OQ197863","node_attrs":{"div":2,"accession":"OQ197863","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Rosales,A.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Rosales,A.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"DC_INS_MPX-1122-H"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OQ197863/2022-10-22"},"date":{"value":"2022-10-22"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C151204T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"]}}},{"name":"OQ644785","node_attrs":{"div":8,"accession":"OQ644785","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00479/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ644785/2022-12-01"},"date":{"value":"2022-12-01"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A713-","G714-","T715-","C3375T","C35216T","C105831T","G134403A","C140075T","G158161A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C183982T","G187156A","G193835A","C196668-","T196669-","T196670-"],"OPG054":["D261N"],"OPG159":["S103F"],"OPG210":["T876M"]},"labels":{"aa":"OPG054: D261N; OPG159: S103F; OPG210: T876M"}}},{"name":"OP289783","node_attrs":{"div":1,"accession":"OP289783","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Mestanza,O.,Lope,P.,Nunez,A.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Mestanza,O.,Lope,P.,Nunez,A."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS-003"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP289783/2022-06-27"},"date":{"value":"2022-06-27"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{}}},{"name":"OP289782","node_attrs":{"div":1,"accession":"OP289782","author":{"author":"Silva,I.,Jimenez,V.,Hurtado,V.,Barcena,L.","value":"Silva,I.,Jimenez,V.,Hurtado,V.,Barcena,L."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS-001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP289782/2022-06-25"},"date":{"value":"2022-06-25"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","-196615A","-196616A","-196617A"]}}},{"name":"OP320551","node_attrs":{"div":1,"accession":"OP320551","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS-018"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP320551/2022-07-09"},"date":{"value":"2022-07-09"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{}}},{"name":"OP320555","node_attrs":{"div":1,"accession":"OP320555","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS-021"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP320555/2022-07-09"},"date":{"value":"2022-07-09"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{}}},{"name":"OP320550","node_attrs":{"div":1,"accession":"OP320550","author":{"author":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G.","value":"Padilla,C.,Silva,I.,Hurtado,V.,Jimenez,V.,Barcena,L.,Lope,P.,Arotinco,G."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LIM-INS-015"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud Peru, Laboratorio de Biotecnologia y Biologia Molecular"},"strain_display":{"value":"Peru/OP320550/2022-07-09"},"date":{"value":"2022-07-09"},"country":{"value":"Peru"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000161","node_attrs":{"div":7,"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C14098T","C84063T","G142493A","G151324A","C170573T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C187332T","C196696-","G196697-","A196698-"],"OPG163":["D98N"],"OPG198":["S179L"]},"labels":{"aa":"OPG163: D98N; OPG198: S179L"}},"children":[{"name":"OR499960","node_attrs":{"div":13,"accession":"OR499960","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00503/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499960/2023-03-15"},"date":{"value":"2023-03-15"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G6746A","C39266T","C63819T","G106927A","G138862A","G169213A"],"OPG083":["V300I"],"OPG125":["T243M"],"OPG156":["S183F"]},"labels":{"aa":"OPG083: V300I; OPG125: T243M; OPG156: S183F"}}},{"name":"NODE_0000162","node_attrs":{"div":9,"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G97749A","G188726A"]}},"children":[{"name":"OQ331003","node_attrs":{"div":9,"accession":"OQ331003","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00392/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ331003/2022-12-06"},"date":{"value":"2022-12-06"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OQ503814","node_attrs":{"div":11,"accession":"OQ503814","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00421/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ503814/2022-12-03"},"date":{"value":"2022-12-03"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A11160G","C108851T"],"OPG023":["F581L"],"OPG128":["D69N"]},"labels":{"aa":"OPG023: F581L; OPG128: D69N"}}}]}]},{"name":"NODE_0000163","node_attrs":{"div":2,"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G132863A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-"]}},"children":[{"name":"OP642375","node_attrs":{"div":4,"accession":"OP642375","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-24590-C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642375/2022-09-07"},"date":{"value":"2022-09-07"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C29887T","C71451T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG091":["H28Y"]},"labels":{"aa":"OPG091: H28Y"}}},{"name":"OP881939","node_attrs":{"div":2,"accession":"OP881939","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-26719E"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP881939/2022-09-29"},"date":{"value":"2022-09-29"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-"]}}},{"name":"OQ148463","node_attrs":{"div":4,"accession":"OQ148463","author":{"author":"Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Orjuela,M.,Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LBMB-UTP_MP-004_TOL"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"strain_display":{"value":"Colombia/OQ148463/2022-09-21"},"date":{"value":"2022-09-21"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G22646A","C85452T"],"OPG038":["P172S"],"OPG106":["G16E"]},"labels":{"aa":"OPG038: P172S; OPG106: G16E"}}},{"name":"OQ696099","node_attrs":{"div":5,"accession":"OQ696099","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.6"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-30518C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ696099/2022-11-09"},"date":{"value":"2022-11-09"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G63811A","G167862A","C170130T"],"OPG193":["D177N"]},"labels":{"aa":"OPG193: D177N"}}}]}]},{"name":"NODE_0000168","node_attrs":{"div":1,"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C70780T"]},"labels":{"clade":"B.1.5"}},"children":[{"name":"OP150925","node_attrs":{"div":1,"accession":"OP150925","author":{"author":"Gigante,C.,Xia,D.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y.","value":"Gigante,C.,Xia,D.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Plipat,N.,Li,Y."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_GA001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP150925/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON959175","node_attrs":{"div":1,"accession":"ON959175","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI162"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/ON959175/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON959154","node_attrs":{"div":1,"accession":"ON959154","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI137"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/ON959154/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"ON918656","node_attrs":{"div":5,"accession":"ON918656","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Taiwan/110-231642/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"strain_display":{"value":"Taiwan/ON918656/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Taiwan"}},"branch_attrs":{"mutations":{"nuc":["C28702T","T34793C","T50861C","C51777T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG054":["T402A"],"OPG070":["V91A"],"OPG071":["E888K"]},"labels":{"aa":"OPG054: T402A; OPG070: V91A; OPG071: E888K"}}},{"name":"ON792322","node_attrs":{"div":1,"accession":"ON792322","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba64538/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"strain_display":{"value":"Switzerland/ON792322/2022-06-02"},"date":{"value":"2022-06-02"},"country":{"value":"Switzerland"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON780017","node_attrs":{"div":1,"accession":"ON780017","author":{"author":"Gramigna,G.,Giombini,E.,Gruber,C.E.M.,Rueca,M.,Carletti,F.,Cicalini,S.,Lapa,D.,Puro,V.,Marani,A.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Rivano Capparuccia,M.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F.","value":"Gramigna,G.,Giombini,E.,Gruber,C.E.M.,Rueca,M.,Carletti,F.,Cicalini,S.,Lapa,D.,Puro,V.,Marani,A.,Fabeni,L.,Butera,O.,Colavita,F.,Meschi,S.,Matusali,G.,Rivano Capparuccia,M.,Specchiarello,E.,Vairo,F.,Vaia,F.,Nicastri,E.,Antinori,A.,Girardi,E.,Maggi,F."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"INMI-Pt4"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"INMI Lazzaro Spallanzani IRCCS, Laboratory of Virology"},"strain_display":{"value":"Italy/ON780017/2022-05-21"},"date":{"value":"2022-05-21"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-196615A"]}}},{"name":"OP245318","node_attrs":{"div":5,"accession":"OP245318","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/PT0064/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP245318/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G71227A","C133867T","C134247T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G158866A"],"OPG090":["E17K"]},"labels":{"aa":"OPG090: E17K"}}},{"name":"OP536756","node_attrs":{"div":3,"accession":"OP536756","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000376"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536756/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C69888T","C150392T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG089":["S8L"],"OPG176":["S195F"]},"labels":{"aa":"OPG089: S8L; OPG176: S195F"}}},{"name":"OP555650","node_attrs":{"div":3,"accession":"OP555650","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0579/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555650/2022-09-10"},"date":{"value":"2022-09-10"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C41022T","A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G159001A"],"OPG060":["R54K"],"OPG153":["D385-"],"OPG185":["D29N"]},"labels":{"aa":"OPG060: R54K; OPG153: D385-; OPG185: D29N"}}},{"name":"OP783902","node_attrs":{"div":1,"accession":"OP783902","author":{"author":"Laubscher,F.,Marques-Melancia,S.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A.","value":"Laubscher,F.,Marques-Melancia,S.,Cordey,S.,Schibler,M.,Kaiser,L.,Renzoni,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-CH-38347314/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University Hospitals of Geneva, Laboratory of Virology"},"strain_display":{"value":"Switzerland/OP783902/2022-06-08"},"date":{"value":"2022-06-08"},"country":{"value":"Switzerland"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ319135","node_attrs":{"div":1,"accession":"OQ319135","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI677"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ319135/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150562-","A150563-","T150564-","G150565-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OQ274885","node_attrs":{"div":1,"accession":"OQ274885","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI666"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ274885/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OQ274886","node_attrs":{"div":1,"accession":"OQ274886","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI667"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ274886/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OQ274884","node_attrs":{"div":1,"accession":"OQ274884","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI665"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ274884/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150551-","A150552-","T150553-","A150554-","T150555-","G150556-","A150557-","T150558-","G150559-","G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A152676-","T152686-","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OQ274883","node_attrs":{"div":1,"accession":"OQ274883","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI664"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ274883/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A152676-","T152686-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OR264398","node_attrs":{"div":5,"accession":"OR264398","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"34_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264398/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["C30283T","C37054T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","G179589A","G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N"}}},{"name":"NODE_0000169","node_attrs":{"div":2,"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C25644T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"]}},"children":[{"name":"ON637939","node_attrs":{"div":2,"accession":"ON637939","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI02"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON637939/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A169745-","C169746-","A169747-","G169748-","A169749-","T169750-","A169751-","C169752-","A169753-","G169754-","A169755-","T169756-","A169757-","C169758-","A169759-","G169760-","A169761-","T169762-","A169763-","C169764-","A169765-","G169766-","A169767-","T169768-","A169769-","C169770-","A169771-","G169772-","A169773-","T169774-","A173292-","T173293-","A173294-","T173295-","A173296-","T173297-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-"],"OPG197":["T26-","D27-","T28-","D29-","T30-","D31-","T32-","D33-","T34-","D35-"]},"labels":{"aa":"OPG197: T26-, D27-, T28-, D29-, T30-, D31-, T32-, D33-, T34-, D35-"}}},{"name":"OQ773463","node_attrs":{"div":4,"accession":"OQ773463","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI844"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ773463/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150564-","G150565-","G156469A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","C190668T"],"OPG016":["R87*"]},"labels":{"aa":"OPG016: R87*"}}}]},{"name":"NODE_0000170","node_attrs":{"div":4,"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G111379A","C160426T","G165326A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A"],"OPG130":["S175L"],"OPG190":["E69K"]},"labels":{"aa":"OPG130: S175L; OPG190: E69K"}},"children":[{"name":"OQ320464","node_attrs":{"div":4,"accession":"OQ320464","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_NY0025"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ320464/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OQ721933","node_attrs":{"div":5,"accession":"OQ721933","author":{"author":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y.","value":"Gigante,C.,Lee,B.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salehi,E.,Li,Y."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_OH0005"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ721933/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G48045A","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","G173318-","G173319-","G173320-","C173321-","A173322-","A173323-","A173324-","A173325-","C173326-","A173327-","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"]}}},{"name":"OQ721932","node_attrs":{"div":9,"accession":"OQ721932","author":{"author":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y.","value":"Gigante,C.,Ruiz,V.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Wang,J.,Li,Y."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_NY0046"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ721932/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","G74391A","G98473A","C124495T","C132962T","C149264T","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-196615A"],"OPG094":["M204I"],"OPG118":["D10N"]},"labels":{"aa":"OPG094: M204I; OPG118: D10N"}}}]},{"name":"NODE_0000171","node_attrs":{"div":2,"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C44333T","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG064":["M522I"]},"labels":{"aa":"OPG064: M522I"}},"children":[{"name":"ON853667","node_attrs":{"div":3,"accession":"ON853667","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI085"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/ON853667/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G46956A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"],"OPG066":["P158L"]},"labels":{"aa":"OPG066: P158L"}}},{"name":"OR035702","node_attrs":{"div":6,"accession":"OR035702","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_96"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035702/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C29315T","C60396T","G149807A","C161572T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG046":["D139N"]},"labels":{"aa":"OPG046: D139N"}}},{"name":"OR035675","node_attrs":{"div":3,"accession":"OR035675","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_69"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035675/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G161488A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000172","node_attrs":{"div":3,"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G93512T"],"OPG113":["K594N"]},"labels":{"aa":"OPG113: K594N"}},"children":[{"name":"OP358276","node_attrs":{"div":6,"accession":"OP358276","author":{"author":"Tramuto,F.","value":"Tramuto,F."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"SIC-AOUP-UNIPA_VL_9aug"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University of Palermo, Department of Health Promotion Sciences Maternal and Infant Care, Internal Medicine and Medical Specialties \"G. D'Alessandro\"\"\""},"strain_display":{"value":"Italy/OP358276/2022-08-09"},"date":{"value":"2022-08-09"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["C33103T","C114490T","C133295T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-"],"OPG049":["E17K"],"OPG133":["D403N"]},"labels":{"aa":"OPG049: E17K; OPG133: D403N"}}},{"name":"OR264417","node_attrs":{"div":4,"accession":"OR264417","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.5"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"43_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264417/2022-06-22"},"date":{"value":"2022-06-22"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["G2898A","C194312T"]}}}]}]}]},{"name":"NODE_0000173","node_attrs":{"div":2,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C89906T","G94798A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG110":["S92F"],"OPG115":["E47K"]},"labels":{"aa":"OPG110: S92F; OPG115: E47K","clade":"B.1.10"}},"children":[{"name":"ON720848","node_attrs":{"div":3,"accession":"ON720848","author":{"author":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D.","value":"Buenestado-Serrano,S.,Palomino-Cabrera,R.,Penas-Utrilla,D.,Rodriguez-Grande,J.,Sola Campoy,P.,Perez-Lago,L.,Rodriguez-Grande,C.,Herranz Martin,M.,Suarez,J.,Catalan,P.,Munoz,P.,Garcia de Viedma,D."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/Spain/MD-HGUGM-6513479/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Microbial Genomics, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, Madrid, Spain"},"strain_display":{"value":"Spain/ON720848/2022-05-27"},"date":{"value":"2022-05-27"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["A327-","T605-","T606-","A1697-","T4296-","T6587-","T6588-","T7253-","G7724-","T8017-","A8036-","T8499-","T9514-","A9869-","T10502-","A10914-","T11188-","C11749-","T11761-","T12121-","A15754-","A17087-","T18866-","A19360-","T20663-","A21081-","T21975-","T24678-","T25853-","T26099-","C27002-","A27114-","C27799-","A28529-","A28530-","T32194-","T33414-","G35949-","T37982-","T39131-","T39866-","T41744-","T42990-","C43014-","G43200-","A43443-","T44120-","T44738-","G46762-","T48675-","A49134-","G49833-","A51022-","A52765-","A54968-","A55124-","T55560-","T56040-","T57075-","A57277-","A58650-","T61749-","A62041-","T63628-","A64728-","A64935-","A65535-","A65967-","T66783-","A66843-","A67164-","C68466-","T68481-","C68899-","G69145-","A69744-","T69768-","A71254-","G71359-","T75833-","A76072-","T76084-","T76085-","A76153-","A76154-","A76890-","A77260-","T77803-","T78062-","A79042-","A79181-","G79217-","C79533T","A79787-","G80950-","C82482-","T84846-","T88095-","T88836-","T88941-","A89106-","T90646-","T91129-","T91370-","A91583-","A91705-","T94795-","A95341-","A95574-","G95742-","G95818-","A97351-","A97480-","A97501-","A97699-","A98683-","T101452-","G101515-","T102437-","T103367-","T103368-","T104279-","T105360-","T106596-","T108598-","A113921-","T113951-","C114431-","T114518-","T114755-","T115127-","G115801-","A116014-","C116494-","T116963-","T121121-","T121122-","G121269-","C121546-","T124022-","T124751-","A125252-","A126568-","T126682-","A126715-","A127250-","A127754-","A132023-","A132024-","T133095-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","T133639-","T136780-","T137886-","A143045-","G143363-","T143478-","A144230-","T146131-","A148000-","A149727-","A150340-","T150538-","T150539-","A150635-","T150864-","A151490-","A151508-","G151545-","A152676-","T152686-","A153358-","A153424-","A153517-","T154862-","T155424-","C156607-","C156608-","A157997-","T163498-","T163597-","A163957-","A165461-","A166740-","G167640-","A167967-","T168120-","A170728-","T170758-","T170903-","T170904-","T172087-","T172667-","G179036-","A179551-","A179950-","T180905-","G181052-","A181253-","C183534-","A183780-","T187080-","A190935-","A191015-","G191519-","A196613-","A196614-","T196888-","T197183-"],"OPG015_dup":["G156-"],"OPG016":["T176-"],"OPG019":["G49-"],"OPG021":["N95-"],"OPG023":["G385-"],"OPG043":["G53-"],"OPG044":["K147-"],"OPG066":["P223-"],"OPG068":["L159-","D545-"],"OPG070":["N145-"],"OPG074":["K523-"],"OPG084":["K3-","K272-","R416-"],"OPG085":["F457-"],"OPG087":["L15-","G97-"],"OPG090":["K26-"],"OPG096":["L83-"],"OPG098":["S121-"],"OPG099":["F47-"],"OPG100":["F19-"],"OPG102":["K33-"],"OPG104":["P24-"],"OPG109":["K206-"],"OPG111":["F128-"],"OPG112":["S42-"],"OPG115":["S46-"],"OPG116":["K72-"],"OPG117":["K435-","N478-","R551-"],"OPG118":["I80-"],"OPG122":["Y4-"],"OPG123":["K569-"],"OPG133":["K394-"],"OPG134":["E18-","P249-"],"OPG139":["P34-"],"OPG145":["F26-","F269-","I436-"],"OPG148":["I195-","F233-"],"OPG149":["K19-"],"OPG151":["K1034-"],"OPG164":["R90-"],"OPG165":["M239-"],"OPG172":["I192-"],"OPG175":["N96-"],"OPG176":["K178-"],"OPG178":["D13-"],"OPG180":["K223-","K276-"],"OPG181":["F151-"],"OPG189":["L56-","K209-"],"OPG190":["N114-"],"OPG192":["K4-"],"OPG193":["G103-","F263-"],"OPG198":["K231-"],"OPG208":["I96-"],"OPG209":["L130-"],"OPG210":["P727-"]},"labels":{"aa":"OPG015_dup: G156-; OPG016: T176-; OPG019: G49-; OPG021: N95-; OPG023: G385-; OPG043: G53-; OPG044: K147-; OPG066: P223-; OPG068: L159-, D545-; OPG070: N145-; OPG074: K523-; OPG084: K3-, K272-, R416-; OPG085: F457-; OPG087: L15-, G97-; OPG090: K26-; OPG096: L83-; OPG098: S121-; OPG099: F47-; OPG100: F19-; OPG102: K33-; OPG104: P24-; OPG109: K206-; OPG111: F128-; OPG112: S42-; OPG115: S46-; OPG116: K72-; OPG117: K435-, N478-, R551-; OPG118: I80-; OPG122: Y4-; OPG123: K569-; OPG133: K394-; OPG134: E18-, P249-; OPG139: P34-; OPG145: F26-, F269-, I436-; OPG148: I195-, F233-; OPG149: K19-; OPG151: K1034-; OPG164: R90-; OPG165: M239-; OPG172: I192-; OPG175: N96-; OPG176: K178-; OPG178: D13-; OPG180: K223-, K276-; OPG181: F151-; OPG189: L56-, K209-; OPG190: N114-; OPG192: K4-; OPG193: G103-, F263-; OPG198: K231-; OPG208: I96-; OPG209: L130-; OPG210: P727-"}}},{"name":"OP205110","node_attrs":{"div":2,"accession":"OP205110","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000147"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205110/2022-06-14"},"date":{"value":"2022-06-14"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OR035722","node_attrs":{"div":5,"accession":"OR035722","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_116"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035722/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C20879T","C60094T","T133102-","G149818A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","T196712-","A196713-","T196714-"],"OPG036":["M62I"],"OPG080":["R642K"],"OPG176":["D4N"]},"labels":{"aa":"OPG036: M62I; OPG080: R642K; OPG176: D4N"}}},{"name":"OQ581847","node_attrs":{"div":15,"accession":"OQ581847","author":{"author":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Munoz-Barrera,A.,Ciuffreda,L.,Alcoba-Florez,J.,Rubio-Rodriguez,L.A.,Rodriguez-Perez,H.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Salas-Hernandez,J.,Rodriguez-Nunez,J.,Inigo-Campos,A.,Garcia-Olivares,V.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0005b/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"strain_display":{"value":"Spain/OQ581847/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["A43453G","A66769C","T88735A","G90070A","C101656T","G104325A","C121681T","G127869A","G132490A","T133095A","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","T139779C","G140866T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C151204T","T176743A"],"OPG063":["L79P"],"OPG085":["V588G"],"OPG109":["E238V"],"OPG110":["D147N"],"OPG123":["A249V"],"OPG150":["G31R"],"OPG160":["S70Y"],"OPG205":["L363*"]},"labels":{"aa":"OPG063: L79P; OPG085: V588G; OPG109: E238V; OPG110: D147N; OPG123: A249V; OPG150: G31R; OPG160: S70Y; OPG205: L363*"}}},{"name":"OR264420","node_attrs":{"div":3,"accession":"OR264420","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"45_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264420/2022-07-10"},"date":{"value":"2022-07-10"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["G63147A","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"NODE_0000174","node_attrs":{"div":3,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C150831T"]}},"children":[{"name":"ON959143","node_attrs":{"div":4,"accession":"ON959143","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX-96/Finland/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"strain_display":{"value":"Finland/ON959143/2022-06-16"},"date":{"value":"2022-06-16"},"country":{"value":"Finland"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C188491T"]}}},{"name":"OP382489","node_attrs":{"div":4,"accession":"OP382489","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00012"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382489/2022-07-19"},"date":{"value":"2022-07-19"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["G109437A","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","G150603-","A150604-","T150605-","A150606-","T150607-","G150608-","A150609-","T150610-","G150611-"],"OPG129":["S523L"],"OPG153":["D384-","D385-"]},"labels":{"aa":"OPG129: S523L; OPG153: D384-, D385-"}}}]},{"name":"NODE_0000175","node_attrs":{"div":3,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G50672A"],"OPG070":["R28K"]},"labels":{"aa":"OPG070: R28K"}},"children":[{"name":"OP642386","node_attrs":{"div":4,"accession":"OP642386","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-24913-O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642386/2022-09-09"},"date":{"value":"2022-09-09"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C121034T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP642392","node_attrs":{"div":3,"accession":"OP642392","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-24520-O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642392/2022-09-07"},"date":{"value":"2022-09-07"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP642388","node_attrs":{"div":3,"accession":"OP642388","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-24915-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642388/2022-09-09"},"date":{"value":"2022-09-09"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OP693650","node_attrs":{"div":4,"accession":"OP693650","author":{"author":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M.","value":"Laiton-Donato,K.,Alvarez-Diaz,D.A.,Franco-Munoz,C.,Ruiz-Moreno,H.A.,Rojas-Estevez,P.,Rosales,A.,Martinez,D.,Flores,A.,Prieto,F.,Walteros,D.,Gomez,S.,Mercado-Reyes,M."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT_INS_MPX_0024_L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP693650/2022-08-07"},"date":{"value":"2022-08-07"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G93624A"],"OPG113":["E632K"]},"labels":{"aa":"OPG113: E632K"}}},{"name":"OP642408","node_attrs":{"div":3,"accession":"OP642408","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-25285O"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642408/2022-09-13"},"date":{"value":"2022-09-13"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-"]}}},{"name":"OQ261707","node_attrs":{"div":4,"accession":"OQ261707","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-28354C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ261707/2022-10-14"},"date":{"value":"2022-10-14"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G148202A"],"OPG173":["E56K"]},"labels":{"aa":"OPG173: E56K"}}},{"name":"OQ148472","node_attrs":{"div":5,"accession":"OQ148472","author":{"author":"Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C.","value":"Tabares,F.A.,Anacona,J.D.,Lopez,P.A.,Orjuela,M.,Zuluaga-Velez,A.,Sepulveda-Arias,J.C."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"LBMB-UTP_MP-019_VAC"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad Tecnologica de Pereira, Laboratorio de Biologia Molecular y Biotecnologia / Facultad de ciencias de la salud"},"strain_display":{"value":"Colombia/OQ148472/2022-11-11"},"date":{"value":"2022-11-11"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C25087T","C62649T"],"OPG040":["R131K"]},"labels":{"aa":"OPG040: R131K"}}},{"name":"NODE_0000176","node_attrs":{"div":4,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G68499A"]}},"children":[{"name":"OQ261709","node_attrs":{"div":6,"accession":"OQ261709","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-28766E"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ261709/2022-10-21"},"date":{"value":"2022-10-21"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C15945T","C158835T","A197010-","T197011-","G197012-"],"OPG027":["D145N"]},"labels":{"aa":"OPG027: D145N"}}},{"name":"OQ261701","node_attrs":{"div":4,"accession":"OQ261701","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-28290C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ261701/2022-10-13"},"date":{"value":"2022-10-13"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","A197133-","T197134-","T197135-"]}}}]},{"name":"NODE_0000177","node_attrs":{"div":8,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","G32863A","G45416A","C72770T","C123118T","C148771T","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-"],"OPG092":["E60K"],"OPG174":["D209N"]},"labels":{"aa":"OPG092: E60K; OPG174: D209N"}},"children":[{"name":"OQ696103","node_attrs":{"div":8,"accession":"OQ696103","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-31501C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ696103/2022-11-22"},"date":{"value":"2022-11-22"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{}}},{"name":"OQ696098","node_attrs":{"div":11,"accession":"OQ696098","author":{"author":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde Hoyos,C.A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-30513C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ696098/2022-11-10"},"date":{"value":"2022-11-10"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A50672G","C67823T","A94798G"],"OPG070":["K28R"],"OPG085":["E237K"],"OPG115":["K47E"]},"labels":{"aa":"OPG070: K28R; OPG085: E237K; OPG115: K47E"}}}]},{"name":"NODE_0000178","node_attrs":{"div":4,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C13624T","-179194A","-179195T","C181355-","A181356-","T181357-","G181358-","A181359-","A181360-","T181361-","T181362-","T181363-","T181364-","C181365-","A181366-","G181367-","A181368-","A181369-","A181370-","T181371-","T181372-"]}},"children":[{"name":"OP642403","node_attrs":{"div":5,"accession":"OP642403","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-25254C"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642403/2022-09-13"},"date":{"value":"2022-09-13"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C120170T","G133051A"],"OPG137":["S190L"]},"labels":{"aa":"OPG137: S190L"}}},{"name":"NODE_0000179","node_attrs":{"div":5,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C43472T","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG063":["E73K"]},"labels":{"aa":"OPG063: E73K"}},"children":[{"name":"OP642398","node_attrs":{"div":5,"accession":"OP642398","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-24939C"},"clade_membership":{"value":"IIb"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642398/2022-09-12"},"date":{"value":"2022-09-12"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{}}},{"name":"OP689664","node_attrs":{"div":5,"accession":"OP689664","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI511"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP689664/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-181355C","-181356A","-181357T","-181358G","-181359A","-181360A","-181361T","-181362T","-181363T","-181364T","-181365C","-181366A","-181367G","-181368A","-181369A","-181370A","-181371T","-181372T"]}}}]}]},{"name":"NODE_0000180","node_attrs":{"div":4,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C49265T"]}},"children":[{"name":"OP459217","node_attrs":{"div":7,"accession":"OP459217","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-23654-O"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia"},"strain_display":{"value":"Colombia/OP459217/2022-08-30"},"date":{"value":"2022-08-30"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C113965T","G150800A","C152191T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG133":["E578K"]},"labels":{"aa":"OPG133: E578K"}}},{"name":"OP819958","node_attrs":{"div":4,"accession":"OP819958","author":{"author":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M.","value":"Laiton-Donato,K.D.,Franco,C.E.,Alvarez-Diaz,D.A.,Ruiz-Moreno,H.A.,Prada,D.A.,Martinez,D.,Mercado-Reyes,M.M."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"QUI_INS_MPX_0967_L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Instituto Nacional de Salud, Direccion de Investigacion en Salud Publica"},"strain_display":{"value":"Colombia/OP819958/2022-10-15"},"date":{"value":"2022-10-15"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G150603-","A150604-","T150605-","A150606-","T150607-","G150608-","A150609-","T150610-","G150611-"]}}},{"name":"OQ261695","node_attrs":{"div":7,"accession":"OQ261695","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-28157C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OQ261695/2022-10-12"},"date":{"value":"2022-10-12"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["A1701-","C1702-","T1703-","G7959A","C19990T","G164476A","T196852-","G196853-","T196854-"],"OPG019":["R127Q"],"OPG034":["D6N"],"OPG189":["E382K"]},"labels":{"aa":"OPG019: R127Q; OPG034: D6N; OPG189: E382K"}}},{"name":"OP959057","node_attrs":{"div":5,"accession":"OP959057","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"SUC-UNIMOL-MPX-293401-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"strain_display":{"value":"Colombia/OP959057/2022-11-10"},"date":{"value":"2022-11-10"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G23118A"]}}},{"name":"NODE_0000181","node_attrs":{"div":5,"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C100007T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"],"OPG118":["S521F"]},"labels":{"aa":"OPG118: S521F"}},"children":[{"name":"OP536764","node_attrs":{"div":5,"accession":"OP536764","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000385"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536764/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-180517A","-180518A","-180519T","-180520G","-180521A","-180522C","-180523G","-180524A","-180525T","-180526A","-180527T","-180528A","-180529C","-180530G","-180531G","-180532A","-180533T","-180534T","A196614-"]}}},{"name":"OP477453","node_attrs":{"div":5,"accession":"OP477453","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-23188-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP477453/2022-08-23"},"date":{"value":"2022-08-23"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{}}},{"name":"OP642379","node_attrs":{"div":5,"accession":"OP642379","author":{"author":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R.","value":"Betancur,I.I.B.,Velarde-Hoyos,C.-A.C.V.,Gomez,R.R.G.,Mercado-Reyes,M.M.R."},"lineage":{"value":"B.1.10"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ANT-LDSP-ANT-MPX-24713-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Laboratorio Departamental de Salud Publica de Antioquia, Antioquia"},"strain_display":{"value":"Colombia/OP642379/2022-09-08"},"date":{"value":"2022-09-08"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000182","node_attrs":{"div":1,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G34308A"],"OPG053":["S128L"]},"labels":{"aa":"OPG053: S128L","clade":"B.1.4"}},"children":[{"name":"ON803417","node_attrs":{"div":3,"accession":"ON803417","author":{"author":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J.","value":"Knox,N.,Duggan,A.,Yadav,C.,Hole,D.,Haidl,E.,Chapel,M.,Jolly,G.,Domselaar,G.V.,Antonation,K.,Leung,A.,Fernando,L.,Audet,J.,Hagan,M.,Graham,M.,Griffiths,E.,Safronetz,D.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2836/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON803417/2022-05-17"},"date":{"value":"2022-05-17"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C69127T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G158750A"],"OPG087":["R91W"]},"labels":{"aa":"OPG087: R91W"}}},{"name":"OP390177","node_attrs":{"div":2,"accession":"OP390177","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"ATL-UNIMOL-MPX-292896-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"strain_display":{"value":"Colombia/OP390177/2022-08-13"},"date":{"value":"2022-08-13"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["C176447T","A180517-","A180518-","T180519-","G180520-","A180521-","C180522-","G180523-","A180524-","T180525-","A180526-","T180527-","A180528-","C180529-","G180530-","G180531-","A180532-","T180533-","T180534-"]}}},{"name":"OQ503748","node_attrs":{"div":6,"accession":"OQ503748","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-108160/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OQ503748/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","G36259A","A80755C","G159203A","G174543A","C177720T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG104":["C89G"],"OPG185":["G96E"],"OPG205":["R689C"]},"labels":{"aa":"OPG104: C89G; OPG185: G96E; OPG205: R689C"}}},{"name":"NODE_0000183","node_attrs":{"div":2,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T85846C"],"OPG107":["M112T"]},"labels":{"aa":"OPG107: M112T"}},"children":[{"name":"ON880532","node_attrs":{"div":2,"accession":"ON880532","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3253/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880532/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C133187-","A133188-","T133189-","T133190-","T133191-","C133192-","A133193-"]}}},{"name":"ON880519","node_attrs":{"div":2,"accession":"ON880519","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Charest,H.,Levade,I.,Fafard,J."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2833/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880519/2022-05-13"},"date":{"value":"2022-05-13"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000184","node_attrs":{"div":4,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C10672T","G112481A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G163626A"],"OPG022":["E63K"]},"labels":{"aa":"OPG022: E63K"}},"children":[{"name":"NODE_0000185","node_attrs":{"div":5,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A87705G"]}},"children":[{"name":"OR126132","node_attrs":{"div":8,"accession":"OR126132","author":{"author":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C.","value":"Ponce-Alonso,M.,Martinez-Garcia,L.,Olavarrieta,L.,Galan,J.C."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"HRYC_MPXV002"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Hospital Ramon y Cajal, Microbiology"},"strain_display":{"value":"Spain/OR126132/2023-03-23"},"date":{"value":"2023-03-23"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["G6376A","G11924A","G21674A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C190834T"],"OPG016":["S142L"],"OPG023":["S326L"],"OPG037":["L254F"]},"labels":{"aa":"OPG016: S142L; OPG023: S326L; OPG037: L254F"}}},{"name":"OR759209","node_attrs":{"div":5,"accession":"OR759209","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL121/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759209/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000186","node_attrs":{"div":6,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C99441T"]}},"children":[{"name":"OR759187","node_attrs":{"div":8,"accession":"OR759187","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL099/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759187/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C153642T","C183429T"],"OPG210":["P692S"]},"labels":{"aa":"OPG210: P692S"}}},{"name":"NODE_0000187","node_attrs":{"div":7,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C111569T"],"OPG130":["D112N"]},"labels":{"aa":"OPG130: D112N"}},"children":[{"name":"OR759185","node_attrs":{"div":7,"accession":"OR759185","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL097/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759185/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"OR759175","node_attrs":{"div":7,"accession":"OR759175","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL087/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759175/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T"]}}},{"name":"OR759157","node_attrs":{"div":7,"accession":"OR759157","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL068/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759157/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000188","node_attrs":{"div":5,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G144478A"]}},"children":[{"name":"ON880511","node_attrs":{"div":5,"accession":"ON880511","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3214/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880511/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"]}}},{"name":"OR759193","node_attrs":{"div":5,"accession":"OR759193","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL105/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759193/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"OR759168","node_attrs":{"div":6,"accession":"OR759168","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL080/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759168/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C4150T","G193060A"],"OPG003":["S153N"],"OPG003_dup":["S153N"]},"labels":{"aa":"OPG003: S153N; OPG003_dup: S153N"}}},{"name":"NODE_0000189","node_attrs":{"div":6,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C143461T"]}},"children":[{"name":"OR759212","node_attrs":{"div":6,"accession":"OR759212","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL124/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759212/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["T606-","A196614-"]}}},{"name":"OR759148","node_attrs":{"div":6,"accession":"OR759148","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL052/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759148/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T","-196615A"]}}}]},{"name":"NODE_0000190","node_attrs":{"div":6,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G170076A"]}},"children":[{"name":"OR759176","node_attrs":{"div":8,"accession":"OR759176","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL088/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759176/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T","C128534T","C151626T"],"OPG178":["Q40*"]},"labels":{"aa":"OPG178: Q40*"}}},{"name":"OR759174","node_attrs":{"div":6,"accession":"OR759174","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL086/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759174/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000191","node_attrs":{"div":5,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C24995T","G85774A","G148427A","G189258A"],"OPG040":["D162N"],"OPG107":["R88K"]},"labels":{"aa":"OPG040: D162N; OPG107: R88K"}},"children":[{"name":"ON983164","node_attrs":{"div":6,"accession":"ON983164","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3558/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON983164/2022-06-09"},"date":{"value":"2022-06-09"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["G167106A"],"OPG192":["E126K"]},"labels":{"aa":"OPG192: E126K"}}},{"name":"ON983163","node_attrs":{"div":5,"accession":"ON983163","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Fernando,L.,Graham,M.,Antonation,K.,Audet,J.,Hagan,M.,Safronetz,D.,Leung,A.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Jolly,G.,Marchand-Austin,A.,Eshaghi,A.,Patel,S.N.,Hasso,M.,Gubbay,J.B.,Olsha,R."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-3532/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON983163/2022-06-07"},"date":{"value":"2022-06-07"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"ON880505","node_attrs":{"div":5,"accession":"ON880505","author":{"author":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Knox,N.,Yadav,C.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Jolly,G.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Griffiths,E.,Leung,A.,Graham,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-2906/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/ON880505/2022-05-20"},"date":{"value":"2022-05-20"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"OP279048","node_attrs":{"div":6,"accession":"OP279048","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-4155/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP279048/2022-06-29"},"date":{"value":"2022-06-29"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C120198T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP279035","node_attrs":{"div":5,"accession":"OP279035","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-4103/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP279035/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP279033","node_attrs":{"div":9,"accession":"OP279033","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-4094/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP279033/2022-07-06"},"date":{"value":"2022-07-06"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","G8373A","C19191T","G103142A","C105161T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A"],"OPG122":["E239K"],"OPG124":["D270N"]},"labels":{"aa":"OPG122: E239K; OPG124: D270N"}}},{"name":"OR759221","node_attrs":{"div":5,"accession":"OR759221","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL133/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759221/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR759227","node_attrs":{"div":7,"accession":"OR759227","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL141/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759227/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["G16076A","G106482A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG027":["S101F"]},"labels":{"aa":"OPG027: S101F"}}},{"name":"OR759211","node_attrs":{"div":6,"accession":"OR759211","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL123/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759211/2022-06-01"},"date":{"value":"2022-06-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G172501A"],"OPG200":["E118K"]},"labels":{"aa":"OPG200: E118K"}}},{"name":"OR759192","node_attrs":{"div":5,"accession":"OR759192","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL104/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759192/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR759177","node_attrs":{"div":11,"accession":"OR759177","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL089/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759177/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T","C13331T","G62952A","G67225A","G100442A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G178818A","C181598T","-196615A"],"OPG085":["S436L"]},"labels":{"aa":"OPG085: S436L"}}},{"name":"OR759156","node_attrs":{"div":6,"accession":"OR759156","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL066/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759156/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-607T","C923A","G127179A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G196287T","-196615A"],"OPG001":["G218V"],"OPG001_dup":["G218V"]},"labels":{"aa":"OPG001: G218V; OPG001_dup: G218V"}}},{"name":"NODE_0000192","node_attrs":{"div":7,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C24282T","G28334A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG044":["E82K"]},"labels":{"aa":"OPG044: E82K"}},"children":[{"name":"OR759181","node_attrs":{"div":8,"accession":"OR759181","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL093/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759181/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C47672T"]}}},{"name":"OR759182","node_attrs":{"div":7,"accession":"OR759182","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL094/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759182/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-196615A"]}}}]},{"name":"NODE_0000193","node_attrs":{"div":6,"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G45236A"]}},"children":[{"name":"OP279043","node_attrs":{"div":6,"accession":"OP279043","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-4140/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP279043/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR759203","node_attrs":{"div":6,"accession":"OR759203","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL115/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759203/2022-06-01"},"date":{"value":"2022-06-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OR759184","node_attrs":{"div":7,"accession":"OR759184","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.4"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL096/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759184/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["G132531A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}}]}]}]},{"name":"NODE_0000194","node_attrs":{"div":1,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C25644T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]},"labels":{"clade":"B.1.7"}},"children":[{"name":"OP205106","node_attrs":{"div":1,"accession":"OP205106","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000143"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205106/2022-06-16"},"date":{"value":"2022-06-16"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OP205101","node_attrs":{"div":2,"accession":"OP205101","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000136"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205101/2022-07-07"},"date":{"value":"2022-07-07"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C174227T"]}}},{"name":"OP205090","node_attrs":{"div":1,"accession":"OP205090","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000102"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205090/2022-06-13"},"date":{"value":"2022-06-13"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OP205081","node_attrs":{"div":1,"accession":"OP205081","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000078"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205081/2022-06-14"},"date":{"value":"2022-06-14"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OP415182","node_attrs":{"div":4,"accession":"OP415182","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_Yob5K4_9000201"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415182/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["G56745A","C88394T","G187367A"],"OPG109":["E352K"]},"labels":{"aa":"OPG109: E352K"}}},{"name":"OP415181","node_attrs":{"div":1,"accession":"OP415181","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_dTfiMV_9000200"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415181/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OP536814","node_attrs":{"div":2,"accession":"OP536814","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000452"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536814/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["A57256G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OP536801","node_attrs":{"div":3,"accession":"OP536801","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000429"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536801/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G160946A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G180608A","T190787-"],"OPG187":["D109N"],"OPG209":["E31K"]},"labels":{"aa":"OPG187: D109N; OPG209: E31K"}}},{"name":"OP536778","node_attrs":{"div":7,"accession":"OP536778","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000400"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536778/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T606-","C66249T","G69081A","C88644A","C104134T","C112638T","A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G186489A","A196614-"],"OPG109":["K268N"],"OPG123":["A313T"],"OPG153":["D385-"],"OPG210":["D1712N"]},"labels":{"aa":"OPG109: K268N; OPG123: A313T; OPG153: D385-; OPG210: D1712N"}}},{"name":"OP536774","node_attrs":{"div":3,"accession":"OP536774","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000396"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536774/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-607T","G50034A","G74200A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A"],"OPG069":["E17K"],"OPG094":["D141N"]},"labels":{"aa":"OPG069: E17K; OPG094: D141N"}}},{"name":"OP536665","node_attrs":{"div":2,"accession":"OP536665","author":{"author":"Gagnon,K.T.","value":"Gagnon,K.T."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-USA-IL-IDPH-004"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Southern Illinois University, Molecular Biology, Microbiology, and Biochemistry"},"strain_display":{"value":"USA/OP536665/2022-06-14"},"date":{"value":"2022-06-14"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G12169A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A","-196616A","-196617A"]}}},{"name":"OP604567","node_attrs":{"div":5,"accession":"OP604567","author":{"author":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T.","value":"Chapman,R.C.,Bernhard,K.,McCutchen,E.L.,Fauver,J.R.,O'Dell,J.X.,Mannell,M.,Wiley,M.R.,Cross,S.T."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV22/human/USA-OK-288"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"University of Nebraska Medical Center, Environmental, Agricultural, and Occupational Health"},"strain_display":{"value":"USA/OP604567/2022-09-12"},"date":{"value":"2022-09-12"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G4236A","C9781T","G49824A","C57550T","A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C192974T","-196615A","-196616A","-196617A"],"OPG068":["E542K"],"OPG153":["D385-"]},"labels":{"aa":"OPG068: E542K; OPG153: D385-"}}},{"name":"OR759205","node_attrs":{"div":1,"accession":"OR759205","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL117/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759205/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"ON843170","node_attrs":{"div":1,"accession":"ON843170","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0031/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/ON843170/2022-05-26"},"date":{"value":"2022-05-26"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OP205070","node_attrs":{"div":1,"accession":"OP205070","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000064"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205070/2022-06-06"},"date":{"value":"2022-06-06"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000195","node_attrs":{"div":2,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G120241A"],"OPG137":["D214N"]},"labels":{"aa":"OPG137: D214N"}},"children":[{"name":"ON911481","node_attrs":{"div":5,"accession":"ON911481","author":{"author":"Galan-Huerta,K.A.,Paz-Infanzon,M.,Ruiz-Higareda,A.F.,Nuzzolo-Shihadeh,L.,Camacho-Ortiz,A.,Bocanegra-Ibarias,P.,Rivas-Estilla,A.M.,Zacarias-Villarreal,D.,Yamallel-Ortega,L.A.,Guerrero-Putz,M.D.,Ocampo-Candiani,J.","value":"Galan-Huerta,K.A.,Paz-Infanzon,M.,Ruiz-Higareda,A.F.,Nuzzolo-Shihadeh,L.,Camacho-Ortiz,A.,Bocanegra-Ibarias,P.,Rivas-Estilla,A.M.,Zacarias-Villarreal,D.,Yamallel-Ortega,L.A.,Guerrero-Putz,M.D.,Ocampo-Candiani,J."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/MX-UANL001/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Universidad Autonoma de Nuevo Leon - Facultad de Medicina, Centro de Investigacion e Innovacion en Virologia Medica"},"strain_display":{"value":"Mexico/ON911481/2022-06-28"},"date":{"value":"2022-06-28"},"country":{"value":"Mexico"}},"branch_attrs":{"mutations":{"nuc":["T606-","G57088A","C127530T","T133098-","T133099-","T133100-","T133101-","T133102-","T168120C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-196615A","-196616A","-196617A"],"OPG074":["S13L"],"OPG149":["S112L"],"OPG193":["F263L"]},"labels":{"aa":"OPG074: S13L; OPG149: S112L; OPG193: F263L"}}},{"name":"OP205071","node_attrs":{"div":2,"accession":"OP205071","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000065"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205071/2022-06-06"},"date":{"value":"2022-06-06"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OQ773452","node_attrs":{"div":2,"accession":"OQ773452","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI833"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ773452/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-"]}}}]},{"name":"NODE_0000198","node_attrs":{"div":3,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G144556A","C170573T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}},"children":[{"name":"OR264460","node_attrs":{"div":3,"accession":"OR264460","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"7_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264460/2022-07-11"},"date":{"value":"2022-07-11"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}},{"name":"OR264459","node_attrs":{"div":3,"accession":"OR264459","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"7_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264459/2022-07-11"},"date":{"value":"2022-07-11"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}},{"name":"OR264370","node_attrs":{"div":3,"accession":"OR264370","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"18_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264370/2022-07-11"},"date":{"value":"2022-07-11"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000199","node_attrs":{"div":2,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G63147A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}},"children":[{"name":"OP536792","node_attrs":{"div":5,"accession":"OP536792","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000418"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536792/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C15004T","C101845T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177780A","-179194A","-179195T","-179196A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG121":["S19F"],"OPG205":["E709K"]},"labels":{"aa":"OPG121: S19F; OPG205: E709K"}}},{"name":"OR264425","node_attrs":{"div":2,"accession":"OR264425","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"48_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264425/2022-08-31"},"date":{"value":"2022-08-31"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000200","node_attrs":{"div":6,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G10224A","G129761A","T143625A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C177847T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","-196615A"],"OPG021":["R213Q"],"OPG151":["D280N"],"OPG165":["I37N"],"OPG205":["S731L"]},"labels":{"aa":"OPG021: R213Q; OPG151: D280N; OPG165: I37N; OPG205: S731L"}},"children":[{"name":"ON927248","node_attrs":{"div":6,"accession":"ON927248","author":{"author":"Chan,W.Y.,Mtshali,P.S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J.","value":"Chan,W.Y.,Mtshali,P.S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"NICD-SVPL232"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Africa"},"institution":{"value":"National Institute for Communicable Disease, Sequencing core facility"},"strain_display":{"value":"South Africa/ON927248/2022-06-24"},"date":{"value":"2022-06-24"},"country":{"value":"South Africa"}},"branch_attrs":{"mutations":{"nuc":["A196601C"]}}},{"name":"ON918611","node_attrs":{"div":6,"accession":"ON918611","author":{"author":"Chan,W.Y.,Mtshali,S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J.","value":"Chan,W.Y.,Mtshali,S.,Grobbelaar,A.,Moolla,N.,Mohale,T.,Lowe,M.,Du Plessis,M.,Ismail,A.,Weyer,J."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"NICD-SVPL223"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Africa"},"institution":{"value":"National Institute for Communicable Disease, Sequencing Core Facility"},"strain_display":{"value":"South Africa/ON918611/2022-06-20"},"date":{"value":"2022-06-20"},"country":{"value":"South Africa"}},"branch_attrs":{"mutations":{"nuc":["-607T"]}}}]}]},{"name":"NODE_0000201","node_attrs":{"div":2,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C14077T"]}},"children":[{"name":"OP205084","node_attrs":{"div":4,"accession":"OP205084","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000093"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205084/2022-05-30"},"date":{"value":"2022-05-30"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C4529T","G155585A","G192681A"],"OPG003":["D27N"],"OPG003_dup":["D27N"]},"labels":{"aa":"OPG003: D27N; OPG003_dup: D27N"}}},{"name":"OP415186","node_attrs":{"div":2,"accession":"OP415186","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_cmjxZM_9000205"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415186/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000202","node_attrs":{"div":3,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G147799A"],"OPG172":["A125T"]},"labels":{"aa":"OPG172: A125T"}},"children":[{"name":"OP205097","node_attrs":{"div":5,"accession":"OP205097","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000130"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205097/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["G37691A","G157353A"]}}},{"name":"OP415199","node_attrs":{"div":3,"accession":"OP415199","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_K1dQNt_9000223"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415199/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000203","node_attrs":{"div":2,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C148771T","A179191-","T179192-","T179193-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG174":["D209N"]},"labels":{"aa":"OPG174: D209N"}},"children":[{"name":"OR449630","node_attrs":{"div":4,"accession":"OR449630","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI916"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR449630/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G69840A","C99542T","G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG118":["S366F"],"OPG193":["F263-"]},"labels":{"aa":"OPG118: S366F; OPG193: F263-"}}},{"name":"NODE_0000204","node_attrs":{"div":3,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G114316A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG133":["H461Y"]},"labels":{"aa":"OPG133: H461Y"}},"children":[{"name":"OR087006","node_attrs":{"div":7,"accession":"OR087006","author":{"author":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P.","value":"Vanmechelen,B.,Wawina-Bokalanga,T.,Logist,A.-S.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_197/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR087006/2022-08-03"},"date":{"value":"2022-08-03"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["C12637T","G53377A","T133102-","C178569T","-179191A","-179192T","-179193T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C182707T"],"OPG210":["S451F"]},"labels":{"aa":"OPG210: S451F"}}},{"name":"NODE_0000205","node_attrs":{"div":4,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G152437A"]}},"children":[{"name":"OQ159026","node_attrs":{"div":5,"accession":"OQ159026","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI631"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ159026/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150547A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179194-","T179195-","A179196-","T179197-","A179198-","C179199-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-","C179208-","A179209-","T179210-","T179211-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","G187677A"]}}},{"name":"OQ627928","node_attrs":{"div":4,"accession":"OQ627928","author":{"author":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F.","value":"Rueca,M.,Tucci,F.G.,Mazzotta,V.,Gramigna,G.,Gruber,C.E.M.,Fabeni,L.,Giombini,E.,Matusali,G.,Pinnetti,C.,Mariano,A.,Butera,O.,Specchiarello,E.,Mondi,A.,Lanini,S.,Carletti,F.,Girardi,E.,Vaia,F.,Nicastri,E.,Antinori,A.,Maggi,F."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"INMI-19442022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases \"L. Spallanzani\"\" - IRCCS, Laboratory of Virology\""},"strain_display":{"value":"Italy/OQ627928/2022-09-14"},"date":{"value":"2022-09-14"},"country":{"value":"Italy"}},"branch_attrs":{"mutations":{"nuc":["-608T","G610-","T611-","A612-"]}}}]}]}]},{"name":"NODE_0000206","node_attrs":{"div":2,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G42504A"]}},"children":[{"name":"OP324503","node_attrs":{"div":3,"accession":"OP324503","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0189/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP324503/2022-06-27"},"date":{"value":"2022-06-27"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-607T","G149478-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G186537A","-196615A"],"OPG175":["G13-"],"OPG210":["E1728K"]},"labels":{"aa":"OPG175: G13-; OPG210: E1728K"}}},{"name":"OP205098","node_attrs":{"div":4,"accession":"OP205098","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000131"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205098/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["C40862T","G95871A"],"OPG116":["E171K"]},"labels":{"aa":"OPG116: E171K"}}},{"name":"OP205076","node_attrs":{"div":2,"accession":"OP205076","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000070"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205076/2022-06-09"},"date":{"value":"2022-06-09"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OP204840","node_attrs":{"div":3,"accession":"OP204840","author":{"author":"Seang,S.,Burrel,S.,Todesco,E.,Leducq,V.,Monsel,G.,Le Pluart,D.,Cordevant,C.,Pourcher,V.,Palich,R.,Charpentier,C.","value":"Seang,S.,Burrel,S.,Todesco,E.,Leducq,V.,Monsel,G.,Le Pluart,D.,Cordevant,C.,Pourcher,V.,Palich,R.,Charpentier,C."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"PatientMPXV"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"APHP Pitie Salpetriere SU, Virology"},"strain_display":{"value":"France/OP204840/2022-06-10"},"date":{"value":"2022-06-10"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","G163250A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196612-","A196613-","A196614-"]}}},{"name":"NODE_0000207","node_attrs":{"div":3,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C115870T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}},"children":[{"name":"OP414387","node_attrs":{"div":7,"accession":"OP414387","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0364/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414387/2022-06-26"},"date":{"value":"2022-06-26"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C5292T","G74267A","A161784T","C176852T","G191918A"],"OPG015":["D289N"],"OPG015_dup":["D289N"],"OPG094":["R163Q"]},"labels":{"aa":"OPG015: D289N; OPG015_dup: D289N; OPG094: R163Q"}}},{"name":"OP414335","node_attrs":{"div":7,"accession":"OP414335","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0301/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414335/2022-06-07"},"date":{"value":"2022-06-07"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C1458T","C1920T","G37739A","G61329A","C65828T","G195290A","G195752A"],"OPG001":["D40N"],"OPG001_dup":["D40N"],"OPG002":["D278N"],"OPG002_dup":["D278N"]},"labels":{"aa":"OPG001: D40N; OPG001_dup: D40N; OPG002: D278N; OPG002_dup: D278N"}}}]}]},{"name":"NODE_0000208","node_attrs":{"div":2,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C57173T"]}},"children":[{"name":"OP205099","node_attrs":{"div":4,"accession":"OP205099","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000133"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205099/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["G56365A","A174924T"]}}},{"name":"NODE_0000209","node_attrs":{"div":3,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C142797T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG164":["S7L"]},"labels":{"aa":"OPG164: S7L"}},"children":[{"name":"OP279036","node_attrs":{"div":3,"accession":"OP279036","author":{"author":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N.","value":"Duggan,A.,Hole,D.,Yadav,C.,Knox,N.,Tyler,A.,Haidl,E.,Chapel,M.,Domselaar,G.V.,Graham,M.,Audet,J.,Fernando,L.,Antonation,K.,Safronetz,D.,Hagan,M.,Peters,G.,Go,A.,Laminman,V.,Kaplen,B.,Leung,A.,Griffiths,E.,Jolly,G.,Eshaghi,A.,Gubbay,J.B.,Hasso,M.,Marchand-Austin,A.,Olsha,R.,Patel,S.N."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/CAN/UN-NML-4112/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"National Microbiology Laboratory, Public Health Agency of Canada"},"strain_display":{"value":"Canada/OP279036/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP480404","node_attrs":{"div":5,"accession":"OP480404","author":{"author":"Deanhardt,B.,Miller,M.,Wang,J.R.","value":"Deanhardt,B.,Miller,M.,Wang,J.R."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/USA/NC-UNC-0003/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"University of North Carolina at Chapel Hill, Department of Genetics"},"strain_display":{"value":"USA/OP480404/2022-08-04"},"date":{"value":"2022-08-04"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-608T","-609T","C74733T","C102889T","A133165-","A133166-","T133167-","C133168-","T133169-","T133170-","T133171-","C133172-","T133173-","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A","-196616A","-196617A"]}}},{"name":"OQ918697","node_attrs":{"div":11,"accession":"OQ918697","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00486/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ918697/2023-02-18"},"date":{"value":"2023-02-18"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C55036T","G73789A","C96914T","C136435T","G158254A","C166803T","C170381T","G178559A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG073":["E36K"],"OPG094":["G4R"],"OPG117":["S289L"],"OPG192":["P25S"],"OPG198":["S115L"]},"labels":{"aa":"OPG073: E36K; OPG094: G4R; OPG117: S289L; OPG192: P25S; OPG198: S115L"}}},{"name":"OR264396","node_attrs":{"div":8,"accession":"OR264396","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"33_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264396/2022-09-07"},"date":{"value":"2022-09-07"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["G14622A","A28529-","A28530-","T76084-","T76085-","G101241A","T133102-","C136244T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C156446T","G174708A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG025":["R216C"],"OPG044":["K147-"],"OPG153":["R475K"],"OPG204":["M59I"]},"labels":{"aa":"OPG025: R216C; OPG044: K147-; OPG153: R475K; OPG204: M59I"}}},{"name":"OR209323","node_attrs":{"div":4,"accession":"OR209323","author":{"author":"Li,C.M.","value":"Li,C.M."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_NC0003"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OR209323/2022-12-XX"},"date":{"value":"2022-12-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T606-","G62268A","A136552-","T136553-","C136554-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","A196614-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OR759200","node_attrs":{"div":3,"accession":"OR759200","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL112/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759200/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"OR759172","node_attrs":{"div":3,"accession":"OR759172","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL084/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759172/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000210","node_attrs":{"div":6,"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C30137T","C55072T","G130068A"],"OPG047":["R353K"],"OPG073":["D24N"],"OPG151":["R382Q"]},"labels":{"aa":"OPG047: R353K; OPG073: D24N; OPG151: R382Q"}},"children":[{"name":"OR759178","node_attrs":{"div":7,"accession":"OR759178","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL090/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759178/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["T606-","G26352A","A196614-"],"OPG042":["A249V"]},"labels":{"aa":"OPG042: A249V"}}},{"name":"OR759165","node_attrs":{"div":6,"accession":"OR759165","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.7"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL077/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759165/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000211","node_attrs":{"div":1,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G74360A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"],"OPG094":["R194H"]},"labels":{"aa":"OPG094: R194H","clade":"B.1.1"}},"children":[{"name":"ON792321","node_attrs":{"div":1,"accession":"ON792321","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba6450e/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"strain_display":{"value":"Switzerland/ON792321/2022-06-02"},"date":{"value":"2022-06-02"},"country":{"value":"Switzerland"}},"branch_attrs":{"mutations":{"nuc":["T9242-","A9243-","A9244-","G9245-","A9246-","G9247-","G9248-","A9249-","G9250-","A9251-","G9252-","G9253-","A9254-","C9255-","A9256-","A19360-","T19361-","C19362-","A19363-","T19364-","T19365-","A43653-","T43654-","T43655-","A49176-","A49177-","T49178-","T49179-","T49180-","T49181-","A49182-","T49183-","T49184-","A49185-","A49186-","C49187-","G49188-","G49189-","T49190-","A49191-","A49192-","T49193-","A79063-","A79064-","T79065-","T79066-","T79067-","T79068-","A79069-","A79070-","T79071-","A79072-","T79073-","A79074-","A79075-","T79076-","A79077-","C79078-","T79079-","T79080-","A79081-","A79082-","A79083-","A79084-","A79085-","T79086-","G79087-","G79088-","A79089-","T79090-","G79091-","T79092-","T79093-","G79094-","T79095-","G79096-","T79097-","C79098-","G79099-","T79100-","T79101-","A79102-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","A152691-","A152692-","T152693-","G152694-","A152695-","C152696-","G152697-","T152698-","A175944-","T175945-","A175946-","T175947-","C175948-","A175949-","A175950-","C179127A","C179136T","T179138A","T179148-","T179157-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179185A","-179186T","-179187A","-179188T","-179189A","-179190T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T180493-","A180494-","T180495-","C180496-","A180497-","T180498-","T180499-"],"OPG063":["D50-"],"OPG068":["N329-","G330-","N331-","T332-","F333-","I334-"],"OPG205":["I97-","S98-","I99-"]},"labels":{"aa":"OPG063: D50-; OPG068: N329-, G330-, N331-, T332-, F333-, I334-; OPG205: I97-, S98-, I99-"}}},{"name":"ON755236","node_attrs":{"div":1,"accession":"ON755236","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI030"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/ON755236/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"ON755252","node_attrs":{"div":2,"accession":"ON755252","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI046"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/ON755252/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C21530T"],"OPG037":["E302K"]},"labels":{"aa":"OPG037: E302K"}}},{"name":"ON694332","node_attrs":{"div":2,"accession":"ON694332","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON694332/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A163211T","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"ON694329","node_attrs":{"div":1,"accession":"ON694329","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI025"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON694329/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A192483-","A192484-","G192485-","T192486-","C192487-","A192488-","T192489-","A192490-","A192491-","G192492-","T192493-","T192494-","A192495-","G192496-","T192497-","T192498-","A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP215268","node_attrs":{"div":3,"accession":"OP215268","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI248"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP215268/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C40937T","G175349A"],"OPG204":["S273N"]},"labels":{"aa":"OPG204: S273N"}}},{"name":"OP215223","node_attrs":{"div":1,"accession":"OP215223","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI234"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP215223/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"OP355564","node_attrs":{"div":1,"accession":"OP355564","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI303"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP355564/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","A188351-"]}}},{"name":"OP628448","node_attrs":{"div":3,"accession":"OP628448","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-082531/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP628448/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","G52232A","C119838T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"],"OPG071":["S736L"]},"labels":{"aa":"OPG071: S736L"}}},{"name":"OP615337","node_attrs":{"div":4,"accession":"OP615337","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI453"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP615337/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C92284T","C116142T","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","G187135A"],"OPG113":["S185L"]},"labels":{"aa":"OPG113: S185L"}}},{"name":"OP555635","node_attrs":{"div":6,"accession":"OP555635","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0564/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555635/2022-09-05"},"date":{"value":"2022-09-05"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C23422T","G54619A","G68997A","C69705T","C156100T"],"OPG039":["E233K"]},"labels":{"aa":"OPG039: E233K"}}},{"name":"OQ547751","node_attrs":{"div":1,"accession":"OQ547751","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI724"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ547751/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}},{"name":"OR264399","node_attrs":{"div":3,"accession":"OR264399","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"36_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264399/2022-06-30"},"date":{"value":"2022-06-30"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","A43500-","T76084-","T76085-","T80846-","T80847-","A89106-","G118500A","T121121-","T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G160406A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","C196772-","A196773-","T196774-"],"OPG044":["K147-"],"OPG136":["T363M"]},"labels":{"aa":"OPG044: K147-; OPG136: T363M"}}},{"name":"OR264392","node_attrs":{"div":1,"accession":"OR264392","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"31_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264392/2022-08-10"},"date":{"value":"2022-08-10"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"]}}},{"name":"OR500079","node_attrs":{"div":6,"accession":"OR500079","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Romania/B-16/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"strain_display":{"value":"Romania/OR500079/2022-08-04"},"date":{"value":"2022-08-04"},"country":{"value":"Romania"}},"branch_attrs":{"mutations":{"nuc":["A31817T","C67289T","G97717T","C133109A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C166374G","T166375G","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG085":["E415K"],"OPG117":["E557*"],"OPG191":["L72G"]},"labels":{"aa":"OPG085: E415K; OPG117: E557*; OPG191: L72G"}}},{"name":"OR500080","node_attrs":{"div":10,"accession":"OR500080","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Romania/B-18/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"strain_display":{"value":"Romania/OR500080/2022-08-16"},"date":{"value":"2022-08-16"},"country":{"value":"Romania"}},"branch_attrs":{"mutations":{"nuc":["G17189T","A55140C","T55141A","T75369C","T91506G","G121663A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","T169776C","A173282G","A173284G","T174471A","G179029T","A179046T","A179081T","A179110T","T179121A","C179127T","T179129-","T179130-","T179139A","-179172A","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190T","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C179672A","C181209T"],"OPG073":["M1W"],"OPG074":["N662M"],"OPG208":["S136Y"]},"labels":{"aa":"OPG073: M1W; OPG074: N662M; OPG208: S136Y"}}},{"name":"OR500078","node_attrs":{"div":1,"accession":"OR500078","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Romania/B-8/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"strain_display":{"value":"Romania/OR500078/2022-06-29"},"date":{"value":"2022-06-29"},"country":{"value":"Romania"}},"branch_attrs":{"mutations":{"nuc":["T92388-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG113":["F220-"]},"labels":{"aa":"OPG113: F220-"}}},{"name":"OP382479","node_attrs":{"div":1,"accession":"OP382479","author":{"author":"Colson,P.","value":"Colson,P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV-IHU00002"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"IHU - Mediterranee Infection, MEPHI"},"strain_display":{"value":"France/OP382479/2022-07-01"},"date":{"value":"2022-07-01"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"ON694333","node_attrs":{"div":1,"accession":"ON694333","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON694333/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP310061","node_attrs":{"div":1,"accession":"OP310061","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-088764/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OP310061/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"NODE_0000212","node_attrs":{"div":2,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G173429A"]}},"children":[{"name":"ON694334","node_attrs":{"div":2,"accession":"ON694334","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Stocker,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI021"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Centre for Biological Threats, Highly Pathogenic Viruses, Robert Koch Institute, Germany"},"strain_display":{"value":"Germany/ON694334/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["A192499-","A192500-","G192501-","T192502-","C192503-","A192504-","T192505-","A192506-","A192507-","G192508-","T192509-","T192510-","A192511-","G192512-","T192513-","T192514-","A192515-","A192516-","G192517-","T192518-","C192519-","A192520-","T192521-","A192522-","A192523-","G192524-","T192525-","T192526-","A192527-","G192528-","T192529-","T192530-"]}}},{"name":"OP204857","node_attrs":{"div":3,"accession":"OP204857","author":{"author":"Rhie,G.-E.","value":"Rhie,G.-E."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P1-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OP204857/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["C786T","C71728T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG091":["A120V"]},"labels":{"aa":"OPG091: A120V"}}}]},{"name":"NODE_0000213","node_attrs":{"div":3,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G145305A","G178435A"],"OPG167":["P35S"]},"labels":{"aa":"OPG167: P35S"}},"children":[{"name":"OP555488","node_attrs":{"div":3,"accession":"OP555488","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0392/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555488/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OR030945","node_attrs":{"div":7,"accession":"OR030945","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_34"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR030945/2022-07-19"},"date":{"value":"2022-07-19"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G23288A","C57919T","A74360G","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G183819A"],"OPG077":["R222K"],"OPG094":["H194R"],"OPG210":["D822N"]},"labels":{"aa":"OPG077: R222K; OPG094: H194R; OPG210: D822N"}}}]},{"name":"NODE_0000216","node_attrs":{"div":4,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C17048T","G93828A","G177009A"],"OPG029":["D8N"],"OPG113":["E700K"],"OPG205":["E452K"]},"labels":{"aa":"OPG029: D8N; OPG113: E700K; OPG205: E452K"}},"children":[{"name":"OQ159028","node_attrs":{"div":5,"accession":"OQ159028","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI633"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ159028/2022-11-XX"},"date":{"value":"2022-11-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C41131T"],"OPG060":["E18K"]},"labels":{"aa":"OPG060: E18K"}}},{"name":"OQ339216","node_attrs":{"div":7,"accession":"OQ339216","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI697"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ339216/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G25098A","A28529-","A28530-","T54142A","G111116A","G150551-","T150564-","G150565-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG044":["K147-"],"OPG130":["R263C"]},"labels":{"aa":"OPG044: K147-; OPG130: R263C"}}},{"name":"OQ735077","node_attrs":{"div":11,"accession":"OQ735077","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0626/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OQ735077/2023-03-21"},"date":{"value":"2023-03-21"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-609T","A615-","C616-","C10929T","C22179T","G39515A","G77076A","G129659A","C129949T","G139167A","C196638-","T196639-"],"OPG023":["E658K"],"OPG151":["E246K"]},"labels":{"aa":"OPG023: E658K; OPG151: E246K"}}}]},{"name":"NODE_0000217","node_attrs":{"div":2,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G155698A"]}},"children":[{"name":"OP555659","node_attrs":{"div":7,"accession":"OP555659","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0592/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555659/2022-09-14"},"date":{"value":"2022-09-14"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G685-","T686-","C21910T","C67207T","G81244A","G109451A","G138237A","-196615A"],"OPG037":["R175K"],"OPG085":["R442K"],"OPG105":["R40K"]},"labels":{"aa":"OPG037: R175K; OPG085: R442K; OPG105: R40K"}}},{"name":"NODE_0000218","node_attrs":{"div":3,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G161575A"]}},"children":[{"name":"OP626115","node_attrs":{"div":3,"accession":"OP626115","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI477"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP626115/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"OR459775","node_attrs":{"div":5,"accession":"OR459775","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P002-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459775/2022-09-02"},"date":{"value":"2022-09-02"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["G14640A","C108843T","G136558C","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG025":["H210Y"],"OPG153":["I370M"]},"labels":{"aa":"OPG025: H210Y; OPG153: I370M"}}},{"name":"OR086942","node_attrs":{"div":3,"accession":"OR086942","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Sinnesael,R.,Ysebaert,L.,Verlinden,J.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_133/Belgium/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR086942/2022-07-05"},"date":{"value":"2022-07-05"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","A151508-","A151509-","T151510-","G151511-","T151512-","C151513-","T151514-","C151515-","G151516-","T151517-","G151518-","G151519-","G151520-","G151521-","C151522-","A151523-","T151524-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196748-","T196749-","C196750-"]}}}]}]},{"name":"NODE_0000219","node_attrs":{"div":6,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C46672T","C56805T","C72314T","C103216T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","T152686-","A169769-","C169770-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C180857T"],"OPG066":["E253K"],"OPG074":["M107I"],"OPG092":["D212N"],"OPG123":["V619I"]},"labels":{"aa":"OPG066: E253K; OPG074: M107I; OPG092: D212N; OPG123: V619I"}},"children":[{"name":"OR500083","node_attrs":{"div":8,"accession":"OR500083","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Romania/B-35_L3/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"strain_display":{"value":"Romania/OR500083/2023-02-15"},"date":{"value":"2023-02-15"},"country":{"value":"Romania"}},"branch_attrs":{"mutations":{"nuc":["C9781T","G127563A","-169769A","-169770C"],"OPG149":["R123Q"]},"labels":{"aa":"OPG149: R123Q"}}},{"name":"OR500082","node_attrs":{"div":6,"accession":"OR500082","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Romania/B-35_L2/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"strain_display":{"value":"Romania/OR500082/2023-01-26"},"date":{"value":"2023-01-26"},"country":{"value":"Romania"}},"branch_attrs":{"mutations":{"nuc":["A169771-","G169772-","A169773-","T169774-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"NODE_0000220","node_attrs":{"div":7,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C127628T"],"OPG149":["P145S"]},"labels":{"aa":"OPG149: P145S"}},"children":[{"name":"OR500081","node_attrs":{"div":8,"accession":"OR500081","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Romania/B-35_L1/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"strain_display":{"value":"Romania/OR500081/2023-01-05"},"date":{"value":"2023-01-05"},"country":{"value":"Romania"}},"branch_attrs":{"mutations":{"nuc":["C16327T"]}}},{"name":"NODE_0000221","node_attrs":{"div":8,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C42674T"],"OPG063":["E339K"]},"labels":{"aa":"OPG063: E339K"}},"children":[{"name":"OR500084","node_attrs":{"div":8,"accession":"OR500084","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Romania/B-35_R1/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"strain_display":{"value":"Romania/OR500084/2023-01-05"},"date":{"value":"2023-01-05"},"country":{"value":"Romania"}},"branch_attrs":{"mutations":{"nuc":["A169771-","G169772-","A169773-","T169774-"],"OPG197":["T34-","D35-"]},"labels":{"aa":"OPG197: T34-, D35-"}}},{"name":"OR500085","node_attrs":{"div":8,"accession":"OR500085","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Romania/B-35_R2/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"strain_display":{"value":"Romania/OR500085/2023-01-26"},"date":{"value":"2023-01-26"},"country":{"value":"Romania"}},"branch_attrs":{"mutations":{"nuc":["-169769A","-169770C"]}}},{"name":"OR500086","node_attrs":{"div":10,"accession":"OR500086","author":{"author":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D.","value":"Hohan,R.,Vlaicu,O.,Banica,L.,Surleac,M.,Paraschiv,S.,Otelea,D."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Romania/B-35_R3/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute for Infectious Diseases 'Matei Bals', Molecular Diagnostics Laboratory"},"strain_display":{"value":"Romania/OR500086/2023-02-15"},"date":{"value":"2023-02-15"},"country":{"value":"Romania"}},"branch_attrs":{"mutations":{"nuc":["G169748A","C179190T","T179192A","T179193A","A179198G","C179199-","A179200-","T179201-","A185438C","C185439A"]}}}]}]}]},{"name":"NODE_0000222","node_attrs":{"div":2,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","C29887T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG044":["K147-"]},"labels":{"aa":"OPG044: K147-"}},"children":[{"name":"OR264455","node_attrs":{"div":2,"accession":"OR264455","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"67_D"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264455/2022-08-25"},"date":{"value":"2022-08-25"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-28529A","-28530A","T76084-","T76085-","T80846-","T80847-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-"],"OPG044":["-147K"]},"labels":{"aa":"OPG044: -147K"}}},{"name":"OR264438","node_attrs":{"div":3,"accession":"OR264438","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"56_D"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264438/2022-09-06"},"date":{"value":"2022-09-06"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["T76084-","T76085-","C89382T"]}}},{"name":"OR264437","node_attrs":{"div":2,"accession":"OR264437","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"56_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264437/2022-09-06"},"date":{"value":"2022-09-06"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}},{"name":"OR264439","node_attrs":{"div":2,"accession":"OR264439","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"56_F"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264439/2022-09-06"},"date":{"value":"2022-09-06"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}},{"name":"OR264424","node_attrs":{"div":2,"accession":"OR264424","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"47_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264424/2022-07-13"},"date":{"value":"2022-07-13"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-28529A","-28530A"],"OPG044":["-147K"]},"labels":{"aa":"OPG044: -147K"}}},{"name":"OR264410","node_attrs":{"div":2,"accession":"OR264410","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"3_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264410/2022-07-29"},"date":{"value":"2022-07-29"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-607T","-28529A","-28530A","-196615A"],"OPG044":["-147K"]},"labels":{"aa":"OPG044: -147K"}}},{"name":"OR264372","node_attrs":{"div":2,"accession":"OR264372","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"19_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264372/2022-08-24"},"date":{"value":"2022-08-24"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["T76084-","T76085-","T80846-","T80847-","A89106-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-","A152675-","A152676-","A165461-"],"OPG190":["N114-"]},"labels":{"aa":"OPG190: N114-"}}}]},{"name":"NODE_0000223","node_attrs":{"div":2,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C22739T"],"OPG038":["E141K"]},"labels":{"aa":"OPG038: E141K"}},"children":[{"name":"ON808413","node_attrs":{"div":2,"accession":"ON808413","author":{"author":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C.","value":"Filipe,A.,Tong,L.,Vattipally,S.B.,Maclean,A.,Gunson,R.,Holden,M.T.G.,Barr,D.,Ho,A.,Palmarini,M.,Rambaut,A.,Robertson,D.L.,Thomson,E.C."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"CVR_MPXV1a"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"MRC University of Glasgow Centre for Virus Research, Viral Genomics and Bioinformatics"},"strain_display":{"value":"United Kingdom/ON808413/2022-05-15"},"date":{"value":"2022-05-15"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T133098-","T133099-","T133100-","T133101-","T133102-","C133103-","A136552-","T136553-","C136554-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OP355578","node_attrs":{"div":4,"accession":"OP355578","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI322"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP355578/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G55993A","G173727A","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","A188351-"],"OPG074":["S378F"]},"labels":{"aa":"OPG074: S378F"}}},{"name":"OP523990","node_attrs":{"div":7,"accession":"OP523990","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI388"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP523990/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G6376A","G13107A","G117345A","C144256T","G170785A","C190834T"],"OPG016":["S142L"],"OPG024":["S41L"],"OPG136":["S748F"],"OPG198":["E250K"]},"labels":{"aa":"OPG016: S142L; OPG024: S41L; OPG136: S748F; OPG198: E250K"}}},{"name":"OP019276","node_attrs":{"div":2,"accession":"OP019276","author":{"author":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W.","value":"Camp,J.V.,Redlberger-Fritz,M.,Aberle,S.W."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMPXV/Austria/MUW1527495/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Medical University of Vienna, Center for Virology"},"strain_display":{"value":"Austria/OP019276/2022-06-21"},"date":{"value":"2022-06-21"},"country":{"value":"Austria"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP626111","node_attrs":{"div":2,"accession":"OP626111","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI473"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP626111/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000225","node_attrs":{"div":3,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C86567T"],"OPG108":["E165K"]},"labels":{"aa":"OPG108: E165K"}},"children":[{"name":"OP215272","node_attrs":{"div":5,"accession":"OP215272","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Jessen,H.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI253"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP215272/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G9245A","G21060A","C174904-","G174905-","T174906-","A174907-","G174908-","G174909-","T174910-","A174911-","T174912-","T174913-","T174914-","A174915-","T174916-","G174917-","T174918-","A174919-","C174920-","C174921-","G174922-","T174923-","A174924-","A174925-","C174926-"],"OPG036":["T2M"],"OPG204":["R125-","R126-","Y127-","L128-","C129-","T130-","V131-","T132-"]},"labels":{"aa":"OPG036: T2M; OPG204: R125-, R126-, Y127-, L128-, C129-, T130-, V131-, T132-"}}},{"name":"OP484684","node_attrs":{"div":3,"accession":"OP484684","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI363"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP484684/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000226","node_attrs":{"div":4,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C22740T","C38937T"],"OPG056":["R33Q"]},"labels":{"aa":"OPG056: R33Q"}},"children":[{"name":"OP555641","node_attrs":{"div":6,"accession":"OP555641","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0570/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555641/2022-09-02"},"date":{"value":"2022-09-02"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G74362A","A136546-","T136547-","C136548-","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","T136555-","A136556-","T136557-","G136558-","A136559-","T136560-","A136561-","T136562-","C136563-","A136564-","T136565-","C136566-","A136567-","T136568-","C136569-","C177240T"],"OPG094":["A195T"],"OPG153":["I370-","I371-","D372-","D373-","D374-","D375-","D376-","D377-"],"OPG205":["Q529*"]},"labels":{"aa":"OPG094: A195T; OPG153: I370-, I371-, D372-, D373-, D374-, D375-, D376-, D377-; OPG205: Q529*"}}},{"name":"NODE_0000227","node_attrs":{"div":5,"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C118523T","A196614-"]}},"children":[{"name":"OP555587","node_attrs":{"div":5,"accession":"OP555587","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0516/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555587/2022-08-17"},"date":{"value":"2022-08-17"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G778-","T779-","A196656-","A196657-"]}}},{"name":"OP555569","node_attrs":{"div":5,"accession":"OP555569","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0494/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555569/2022-08-15"},"date":{"value":"2022-08-15"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}}]}]}]}]},{"name":"NODE_0000228","node_attrs":{"div":1,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","G186165A"],"OPG210":["D1604N"]},"labels":{"aa":"OPG210: D1604N","clade":"B.1.2"}},"children":[{"name":"ON929079","node_attrs":{"div":1,"accession":"ON929079","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI124"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/ON929079/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"]}}},{"name":"OP331334","node_attrs":{"div":1,"accession":"OP331334","author":{"author":"Grove,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Grove,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000060"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP331334/2022-06-07"},"date":{"value":"2022-06-07"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP415208","node_attrs":{"div":6,"accession":"OP415208","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_Fap1fz_9000234"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415208/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T606-","C24282T","G24622A","C49694T","C92375T","G94221A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG040":["S286L"],"OPG113":["E831K"]},"labels":{"aa":"OPG040: S286L; OPG113: E831K"}}},{"name":"OP415203","node_attrs":{"div":1,"accession":"OP415203","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_fZLVcc_9000228"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415203/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OQ330980","node_attrs":{"div":5,"accession":"OQ330980","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00363/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ330980/2022-10-07"},"date":{"value":"2022-10-07"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C28321T","C68714T","C94102T","A121162G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"],"OPG113":["T791I"]},"labels":{"aa":"OPG113: T791I"}}},{"name":"OR449688","node_attrs":{"div":2,"accession":"OR449688","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI974"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR449688/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G118391A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"OR449671","node_attrs":{"div":1,"accession":"OR449671","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI957"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR449671/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150551-","T150564-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","C179190-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"],"OPG193":["F263-"]},"labels":{"aa":"OPG193: F263-"}}},{"name":"OP150927","node_attrs":{"div":1,"accession":"OP150927","author":{"author":"Gigante,C.,Pavlick,J.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y.","value":"Gigante,C.,Pavlick,J.,Seabolt,M.,Zhao,H.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Parrott,T.,Li,Y."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_WA001"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP150927/2022-05-XX"},"date":{"value":"2022-05-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR035718","node_attrs":{"div":1,"accession":"OR035718","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_112"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035718/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000230","node_attrs":{"div":3,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C3405T","G5375A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","C191835T","G193805A"],"OPG015":["A261V"],"OPG015_dup":["A261V"]},"labels":{"aa":"OPG015: A261V; OPG015_dup: A261V"}},"children":[{"name":"OQ503812","node_attrs":{"div":10,"accession":"OQ503812","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00419/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ503812/2022-11-22"},"date":{"value":"2022-11-22"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C72914T","C112712T","G129749A","G133004A","G154098A","C166171T","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G182486A"],"OPG092":["D12N"],"OPG132":["D277N"],"OPG151":["E276K"],"OPG191":["S4L"]},"labels":{"aa":"OPG092: D12N; OPG132: D277N; OPG151: E276K; OPG191: S4L"}}},{"name":"OR759146","node_attrs":{"div":4,"accession":"OR759146","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL053/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759146/2022-08-01"},"date":{"value":"2022-08-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["C170573T","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}}}]},{"name":"NODE_0000231","node_attrs":{"div":12,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A670-","A671-","G2126A","G10224A","T39348C","C64132T","A78942G","T130733C","G138728A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C154736T","A155151C","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","G183791A","T187664C","C195084T","T196774-","A196775-","A196776-"],"OPG002":["S209L"],"OPG002_dup":["S209L"],"OPG021":["R213Q"],"OPG057":["D283G"],"OPG083":["M195I"],"OPG101":["T153A"],"OPG151":["C604R"],"OPG156":["H228Y"],"OPG181":["P109S","E247A"]},"labels":{"aa":"OPG002: S209L; OPG002_dup: S209L; OPG021: R213Q; OPG057: D283G; OPG083: M195I; OPG101: T153A; OPG151: C604R; OPG156: H228Y; OPG181: P109S, E247A"}},"children":[{"name":"OR178742","node_attrs":{"div":12,"accession":"OR178742","author":{"author":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J.","value":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000194/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDPH, VRDL"},"strain_display":{"value":"USA/OR178742/2023-02-14"},"date":{"value":"2023-02-14"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G669-"]}}},{"name":"OR178741","node_attrs":{"div":13,"accession":"OR178741","author":{"author":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J.","value":"Kath,C.,Haw,M.,Espinosa,A.,Hacker,J."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/CACDPH1MPX1000193/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDPH, VRDL"},"strain_display":{"value":"USA/OR178741/2023-02-14"},"date":{"value":"2023-02-14"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-670A","-671A","A31053G","-196774T","-196775A","-196776A"],"OPG047":["C48R"]},"labels":{"aa":"OPG047: C48R"}}}]},{"name":"NODE_0000232","node_attrs":{"div":3,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G143789A","C147168T","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG165":["D92N"],"OPG171":["L61F"]},"labels":{"aa":"OPG165: D92N; OPG171: L61F"}},"children":[{"name":"OP205080","node_attrs":{"div":4,"accession":"OP205080","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000076"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205080/2022-06-09"},"date":{"value":"2022-06-09"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["G61253A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG080":["R256C"]},"labels":{"aa":"OPG080: R256C"}}},{"name":"NODE_0000233","node_attrs":{"div":4,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C20992T"],"OPG036":["D25N"]},"labels":{"aa":"OPG036: D25N"}},"children":[{"name":"OP626125","node_attrs":{"div":5,"accession":"OP626125","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI487"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP626125/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C61780T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-"],"OPG080":["R80K"]},"labels":{"aa":"OPG080: R80K"}}},{"name":"OR449692","node_attrs":{"div":6,"accession":"OR449692","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI978"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR449692/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G61253A","G95871A","G150551-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","T168120-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"],"OPG080":["R256C"],"OPG116":["E171K"],"OPG193":["F263-"]},"labels":{"aa":"OPG080: R256C; OPG116: E171K; OPG193: F263-"}}},{"name":"OR264415","node_attrs":{"div":4,"accession":"OR264415","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"42_F"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264415/2022-06-22"},"date":{"value":"2022-06-22"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OR264412","node_attrs":{"div":4,"accession":"OR264412","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"42_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264412/2022-06-08"},"date":{"value":"2022-06-08"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["C133103T","G133104-","A133105-","A133106-","A133201-","C133202-","C133203-","T133204-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-","G179281-","A179282-","T196669-","T196670-","T196671-"]}}},{"name":"OR264414","node_attrs":{"div":4,"accession":"OR264414","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"42_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264414/2022-06-22"},"date":{"value":"2022-06-22"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264416","node_attrs":{"div":4,"accession":"OR264416","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"42_G"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264416/2022-06-22"},"date":{"value":"2022-06-22"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OR264413","node_attrs":{"div":4,"accession":"OR264413","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"42_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264413/2022-06-22"},"date":{"value":"2022-06-22"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"NODE_0000236","node_attrs":{"div":5,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C29229T"],"OPG045":["D12N"]},"labels":{"aa":"OPG045: D12N"}},"children":[{"name":"OP205089","node_attrs":{"div":7,"accession":"OP205089","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000101"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205089/2022-06-09"},"date":{"value":"2022-06-09"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["G149561A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G182486A"]}}},{"name":"NODE_0000237","node_attrs":{"div":6,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C57492T","-179194A","-179195T","-179199C","-179200A","-179201T","-179203A","-179205A","-179208C","-179209A","-179210T","-179211T"],"OPG075":["E3K"]},"labels":{"aa":"OPG075: E3K"}},"children":[{"name":"OP205140","node_attrs":{"div":6,"accession":"OP205140","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000193"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205140/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000238","node_attrs":{"div":11,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G10475A","G23462A","G73939A","T147168C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C171808T","-179196A","-179197T","-179198A","-179202T","-179204T","-179206T","-179207A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG094":["D54N"],"OPG171":["F61L"],"OPG199":["S274L"]},"labels":{"aa":"OPG094: D54N; OPG171: F61L; OPG199: S274L"}},"children":[{"name":"OP536807","node_attrs":{"div":11,"accession":"OP536807","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000438"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536807/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OP536763","node_attrs":{"div":11,"accession":"OP536763","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000384"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536763/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}}]}]}]}]}]},{"name":"NODE_0000239","node_attrs":{"div":2,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C188391T"]}},"children":[{"name":"OP215262","node_attrs":{"div":3,"accession":"OP215262","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI238"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP215262/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C179181-","C179190-","G182303A"]}}},{"name":"OP205086","node_attrs":{"div":2,"accession":"OP205086","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000097"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205086/2022-06-06"},"date":{"value":"2022-06-06"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP539914","node_attrs":{"div":2,"accession":"OP539914","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00129/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP539914/2022-09-09"},"date":{"value":"2022-09-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179181-","C179190-","T179244-"]}}},{"name":"OP539909","node_attrs":{"div":2,"accession":"OP539909","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX/Human/USA/CA-LACPHL-MA00124/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OP539909/2022-09-09"},"date":{"value":"2022-09-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179181-","C179190-","G196753-","G196754-","T196755-"]}}},{"name":"OP536784","node_attrs":{"div":2,"accession":"OP536784","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000408"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536784/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP605583","node_attrs":{"div":7,"accession":"OP605583","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-42-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605583/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["A161-","-607T","C17614A","C27187T","G111484A","G147305A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C159401A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG030":["V74L"],"OPG043":["D257N"],"OPG130":["T140I"],"OPG185":["S162Y"]},"labels":{"aa":"OPG030: V74L; OPG043: D257N; OPG130: T140I; OPG185: S162Y"}}},{"name":"OP879767","node_attrs":{"div":2,"accession":"OP879767","author":{"author":"Palmateer,N.C.","value":"Palmateer,N.C."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"NJ-MPXV-054"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"New Jersey Department of Health, Public Health and Environmental Laboratories"},"strain_display":{"value":"USA/OP879767/2022-07-25"},"date":{"value":"2022-07-25"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179181-","C179190-"]}}},{"name":"OP687929","node_attrs":{"div":4,"accession":"OP687929","author":{"author":"Gigante,C.M.,Maloney,M.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Morrison,S.S.,Seabolt,M.H.,Weigand,M.R.,Knipe,K.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Pearson,C.,Li,Y.","value":"Gigante,C.M.,Maloney,M.,Zhao,H.,Batra,D.,Hetrick,E.E.,Howard,D.T.,Kovar,L.,Morrison,S.S.,Seabolt,M.H.,Weigand,M.R.,Knipe,K.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Pearson,C.,Li,Y."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_CT0004"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OP687929/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C22880T","G62253A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG038":["E94K"]},"labels":{"aa":"OPG038: E94K"}}},{"name":"OQ348860","node_attrs":{"div":11,"accession":"OQ348860","author":{"author":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J.","value":"Probert,W.,Espinosa,A.,Kath,C.,Haw,M.,O'Neil,R.,Bell,J.,Hacker,J."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/CA-CDPH-1MPX1000112/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDPH, VRDL"},"strain_display":{"value":"USA/OQ348860/2022-12-14"},"date":{"value":"2022-12-14"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C7705T","C39334G","G50617A","G62896A","G89947A","C110394T","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","G150753A","A158920T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G183899A"],"OPG057":["A288P"],"OPG070":["D10N"],"OPG082":["S186L"],"OPG110":["E106K"],"OPG129":["R204Q"],"OPG185":["T2S"]},"labels":{"aa":"OPG057: A288P; OPG070: D10N; OPG082: S186L; OPG110: E106K; OPG129: R204Q; OPG185: T2S"}}},{"name":"OQ330997","node_attrs":{"div":6,"accession":"OQ330997","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox virus/Human/USA/CA-LACPHL-MA00390/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ330997/2022-12-14"},"date":{"value":"2022-12-14"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G4248A","C100938T","G146665A","G159103A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C192962T"],"OPG120":["E271K"],"OPG185":["D63N"]},"labels":{"aa":"OPG120: E271K; OPG185: D63N"}}},{"name":"OQ503828","node_attrs":{"div":9,"accession":"OQ503828","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00405/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ503828/2023-01-10"},"date":{"value":"2023-01-10"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A662-","C663-","A664-","G25309A","G28271A","G112785A","T118096C","G133968T","C165231T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179181-","C179190-","C180371T","T196635-","C196636-","T196637-"],"OPG040":["S57L"],"OPG044":["D61N"],"OPG136":["M498V"],"OPG190":["S37L"]},"labels":{"aa":"OPG040: S57L; OPG044: D61N; OPG136: M498V; OPG190: S37L"}}},{"name":"OQ979625","node_attrs":{"div":10,"accession":"OQ979625","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-012937/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OQ979625/2023-01-XX"},"date":{"value":"2023-01-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A63108T","G77907A","G92718A","C136554T","G148238A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C167676T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G180523A","G180531A","G180827A"],"OPG099":["M81I"],"OPG113":["E330K"],"OPG153":["D372N"],"OPG173":["D68N"],"OPG193":["H115Y"],"OPG209":["G5E","E104K"]},"labels":{"aa":"OPG099: M81I; OPG113: E330K; OPG153: D372N; OPG173: D68N; OPG193: H115Y; OPG209: G5E, E104K"}}},{"name":"OQ702779","node_attrs":{"div":4,"accession":"OQ702779","author":{"author":"Gigante,C.,Haydel,D.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salinas,A.,Li,Y.","value":"Gigante,C.,Haydel,D.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Cintron,R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Salinas,A.,Li,Y."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_LA0009"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ702779/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C85811T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188491T"]}}},{"name":"OQ644778","node_attrs":{"div":3,"accession":"OQ644778","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00472/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ644778/2022-11-10"},"date":{"value":"2022-11-10"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T606-","G23127A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179181-","C179190-","A196614-"]}}},{"name":"OR464207","node_attrs":{"div":6,"accession":"OR464207","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_TX0054"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OR464207/2022-12-XX"},"date":{"value":"2022-12-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T606-","G45781A","G71465A","G96778A","G145287A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A196614-"],"OPG064":["H40Y"],"OPG117":["E244K"],"OPG167":["P41S"]},"labels":{"aa":"OPG064: H40Y; OPG117: E244K; OPG167: P41S"}}},{"name":"NODE_0000240","node_attrs":{"div":4,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A20156G","C170573T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179181-","C179190-"],"OPG198":["S179L"]},"labels":{"aa":"OPG198: S179L"}},"children":[{"name":"OP597793","node_attrs":{"div":4,"accession":"OP597793","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MN-MDH-MPXV_0019"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Minnesota Department of Health"},"strain_display":{"value":"USA/OP597793/2022-07-20"},"date":{"value":"2022-07-20"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR353582","node_attrs":{"div":5,"accession":"OR353582","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MN-MDH-MPXV_0072"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Minnesota Department of Health, Public Health Laboratory"},"strain_display":{"value":"USA/OR353582/2022-09-07"},"date":{"value":"2022-09-07"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C185818T"],"OPG210":["S1488L"]},"labels":{"aa":"OPG210: S1488L"}}}]},{"name":"NODE_0000241","node_attrs":{"div":7,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T26669C","G96073A","G115235A","C125294T","C135868T","A150586-","T150587-","A150588-","T150589-","A150591-","T150592-","A150595-","T150596-","A150597-","T150598-","A150600-","T150601-"],"OPG117":["D9N"]},"labels":{"aa":"OPG117: D9N"}},"children":[{"name":"OQ159027","node_attrs":{"div":8,"accession":"OQ159027","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI632"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ159027/2022-11-XX"},"date":{"value":"2022-11-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G77052A","-150586A","-150587T","-150588A","-150589T","-150591A","-150592T","-150595A","-150596T","-150597A","-150598T","-150600A","-150601T","C179181-","C179190-"]}}},{"name":"OP959061","node_attrs":{"div":7,"accession":"OP959061","author":{"author":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D.","value":"Loyola,S.,Fernandez-Ruiz,M.,Torres-Pacheco,J.,Franco-Munoz,C.,Laiton-Donato,K.,Ruiz-Moreno,H.,Mercado-Reyes,M.,Gomez-Camargo,D."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"BOL-UNIMOL-MPX-293613-L"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"South America"},"institution":{"value":"Universidad de Cartagena, Laboratorio de Investigacion Molecular (UNIMOL)"},"strain_display":{"value":"Colombia/OP959061/2022-10-11"},"date":{"value":"2022-10-11"},"country":{"value":"Colombia"}},"branch_attrs":{"mutations":{"nuc":["G150590-","G150593-","G150594-","G150599-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000242","node_attrs":{"div":3,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T157527C","C179181-","C179190-"]}},"children":[{"name":"ON813262","node_attrs":{"div":3,"accession":"ON813262","author":{"author":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Uddin,S.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI062"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/ON813262/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"OP555483","node_attrs":{"div":4,"accession":"OP555483","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0387/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555483/2022-07-12"},"date":{"value":"2022-07-12"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G154098A"]}}},{"name":"OP689671","node_attrs":{"div":5,"accession":"OP689671","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI518"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP689671/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C34258T","T100218C","G173153A"],"OPG053":["A145T"]},"labels":{"aa":"OPG053: A145T"}}},{"name":"OQ773512","node_attrs":{"div":7,"accession":"OQ773512","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/ON/RKI893"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ773512/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G150087A","C156429T","C156509T","G177872A","-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}}]},{"name":"NODE_0000243","node_attrs":{"div":6,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G8638A","C21548T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","C188236T","C188339T"],"OPG037":["D296N"]},"labels":{"aa":"OPG037: D296N"}},"children":[{"name":"OQ503752","node_attrs":{"div":6,"accession":"OQ503752","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-118017/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OQ503752/2022-11-XX"},"date":{"value":"2022-11-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","-196615A"]}}},{"name":"NODE_0000244","node_attrs":{"div":8,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C47820T","C68218T"],"OPG085":["R105Q"]},"labels":{"aa":"OPG085: R105Q"}},"children":[{"name":"OR427346","node_attrs":{"div":8,"accession":"OR427346","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-048416/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR427346/2023-04-XX"},"date":{"value":"2023-04-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T133102-"]}}},{"name":"OR427343","node_attrs":{"div":9,"accession":"OR427343","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-038917/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR427343/2023-03-XX"},"date":{"value":"2023-03-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G100939A"]}}},{"name":"OR427340","node_attrs":{"div":8,"accession":"OR427340","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-028603/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR427340/2023-02-XX"},"date":{"value":"2023-02-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR427341","node_attrs":{"div":10,"accession":"OR427341","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-039072/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR427341/2023-03-XX"},"date":{"value":"2023-03-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G156482A","C175867T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG205":["S71F"]},"labels":{"aa":"OPG205: S71F"}}},{"name":"NODE_0000245","node_attrs":{"div":9,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C102741T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG122":["S105L"]},"labels":{"aa":"OPG122: S105L"}},"children":[{"name":"OQ979621","node_attrs":{"div":9,"accession":"OQ979621","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-042823/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OQ979621/2023-04-XX"},"date":{"value":"2023-04-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR499962","node_attrs":{"div":9,"accession":"OR499962","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00505/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499962/2023-04-12"},"date":{"value":"2023-04-12"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499953","node_attrs":{"div":9,"accession":"OR499953","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00496/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499953/2023-04-26"},"date":{"value":"2023-04-26"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000246","node_attrs":{"div":10,"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G12239A","G12488A","-196615A"],"OPG023":["S138L","S221F"]},"labels":{"aa":"OPG023: S138L, S221F"}},"children":[{"name":"OQ979624","node_attrs":{"div":10,"accession":"OQ979624","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-028492/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OQ979624/2023-02-XX"},"date":{"value":"2023-02-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR427347","node_attrs":{"div":10,"accession":"OR427347","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-025109/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR427347/2023-02-XX"},"date":{"value":"2023-02-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR427345","node_attrs":{"div":11,"accession":"OR427345","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.2"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-036395/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR427345/2023-03-XX"},"date":{"value":"2023-03-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T607-","G12748A","A196615-"]}}}]}]}]}]}]},{"name":"NODE_0000247","node_attrs":{"div":1,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G53326A"]}},"children":[{"name":"NODE_0000248","node_attrs":{"div":6,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A61383C","G63100A","G141114A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G153562A","C177155T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-"],"OPG082":["S118L"],"OPG161":["E5K"],"OPG180":["E291K"]},"labels":{"aa":"OPG082: S118L; OPG161: E5K; OPG180: E291K"}},"children":[{"name":"OP751212","node_attrs":{"div":7,"accession":"OP751212","author":{"author":"Bajwa,M.I.,Miller,H.","value":"Bajwa,M.I.,Miller,H."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"B1118383"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Delaware Public Health Lab, Sequencing/Bioinformatics"},"strain_display":{"value":"USA/OP751212/2022-08-30"},"date":{"value":"2022-08-30"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C136081T"]}}},{"name":"OP751213","node_attrs":{"div":6,"accession":"OP751213","author":{"author":"Bajwa,M.I.,Miller,H.","value":"Bajwa,M.I.,Miller,H."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"B1118385"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Delaware Public Health Lab, Sequencing/Bioinformatics"},"strain_display":{"value":"USA/OP751213/2022-08-30"},"date":{"value":"2022-08-30"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000249","node_attrs":{"div":2,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C121104T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A"],"OPG138":["R10K"]},"labels":{"aa":"OPG138: R10K"}},"children":[{"name":"OR264430","node_attrs":{"div":3,"accession":"OR264430","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"51_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264430/2022-09-05"},"date":{"value":"2022-09-05"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-607T","C15582T","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","-196615A"]}}},{"name":"NODE_0000250","node_attrs":{"div":4,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A28529-","A28530-","T133102-","C134102T","G177009A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG044":["K147-"],"OPG205":["E452K"]},"labels":{"aa":"OPG044: K147-; OPG205: E452K"}},"children":[{"name":"OR264447","node_attrs":{"div":4,"accession":"OR264447","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"63_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264447/2022-08-22"},"date":{"value":"2022-08-22"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["T76084-","T76085-"]}}},{"name":"OR264378","node_attrs":{"div":4,"accession":"OR264378","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"25_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264378/2022-08-22"},"date":{"value":"2022-08-22"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["T133101-","T172087-"]}}}]},{"name":"NODE_0000251","node_attrs":{"div":5,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","G57661A","A118917C","C187452T","-196615A"],"OPG077":["S308L"],"OPG136":["I224S"]},"labels":{"aa":"OPG077: S308L; OPG136: I224S"}},"children":[{"name":"OR264457","node_attrs":{"div":6,"accession":"OR264457","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"68_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264457/2022-08-26"},"date":{"value":"2022-08-26"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["T607-","A28529-","A28530-","C62868T","T76084-","T76085-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196615-"],"OPG044":["K147-"]},"labels":{"aa":"OPG044: K147-"}}},{"name":"OR264427","node_attrs":{"div":5,"accession":"OR264427","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"4_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264427/2022-05-19"},"date":{"value":"2022-05-19"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR264394","node_attrs":{"div":5,"accession":"OR264394","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"32_B"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264394/2022-08-24"},"date":{"value":"2022-08-24"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-"]}}}]},{"name":"NODE_0000252","node_attrs":{"div":7,"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C7034T","A28529-","A28530-","G70190A","G144895A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G187827A","C190276T"],"OPG044":["K147-"],"OPG089":["E109K"]},"labels":{"aa":"OPG044: K147-; OPG089: E109K"}},"children":[{"name":"OR264452","node_attrs":{"div":7,"accession":"OR264452","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"66_C"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264452/2022-08-25"},"date":{"value":"2022-08-25"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["T133096-","T133097-","T133098-","T133099-","T133100-","T133101-","T133102-"]}}},{"name":"OR264436","node_attrs":{"div":7,"accession":"OR264436","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"55_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264436/2022-08-09"},"date":{"value":"2022-08-09"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{"nuc":["-28529A","-28530A","T76084-","T76085-"],"OPG044":["-147K"]},"labels":{"aa":"OPG044: -147K"}}},{"name":"OR264369","node_attrs":{"div":7,"accession":"OR264369","author":{"author":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I.","value":"Taouk,M.L.,Steinig,E.,Taiaroa,G.,Savic,I."},"lineage":{"value":"B.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"16_A"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Oceania"},"institution":{"value":"The Peter Doherty Institute for Infection and Immunity at the University of Melbourne, Department of Infectious Diseases"},"strain_display":{"value":"Australia/OR264369/2022-08-08"},"date":{"value":"2022-08-08"},"country":{"value":"Australia"}},"branch_attrs":{"mutations":{}}}]}]},{"name":"NODE_0000253","node_attrs":{"div":3,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C164385T","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","C187620T"]},"labels":{"clade":"B.1.20"}},"children":[{"name":"OQ320441","node_attrs":{"div":3,"accession":"OQ320441","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Sheth,M.R.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_TX0040"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ320441/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-607T","T133102-","A173298-","T173299-","A173300-","T173301-","A173302-","T173303-","A173304-","T173305-","A173306-","T173307-","A173308-","T173309-","A173310-","T173311-","A173312-","T173313-","A173314-","T173315-","A173316-","T173317-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179190C","-179199C","-196615A"]}}},{"name":"NODE_0000254","node_attrs":{"div":4,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T602-","T603-","T604-","T605-","T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G177398A","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","A196610-","A196611-","A196612-","A196613-","A196614-"]}},"children":[{"name":"OQ918695","node_attrs":{"div":4,"accession":"OQ918695","author":{"author":"Hemarajata,P.,Green,N.M.,Garrigues,J.M.","value":"Hemarajata,P.,Green,N.M.,Garrigues,J.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00484/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories, Los Angeles County Department of Public Health"},"strain_display":{"value":"USA/OQ918695/2023-02-07"},"date":{"value":"2023-02-07"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179190C","-179199C","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OR464208","node_attrs":{"div":6,"accession":"OR464208","author":{"author":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y.","value":"Gigante,C.,Kubin,G.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Mcgrath,D.,Takakuwa,J.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,Mccollum,A.,Hutson,C.,Davidson,W.,Rao,A.,White,S.,Li,Y."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_TX0055"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OR464208/2022-12-XX"},"date":{"value":"2022-12-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G129761A","G150577-","A150578-","T150579-","A150580-","T150581-","G150582-","A150583-","T150584-","G150585-","T165597C","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-"],"OPG151":["D280N"],"OPG190":["V159A"]},"labels":{"aa":"OPG151: D280N; OPG190: V159A"}}},{"name":"NODE_0000255","node_attrs":{"div":5,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C177899T","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","A179191-","T179192-","T179193-","A179194-","T179195-","A179196-","T179197-","A179198-","A179200-","T179201-","T179202-","A179203-","T179204-","A179205-","T179206-","A179207-"]}},"children":[{"name":"OR500006","node_attrs":{"div":5,"accession":"OR500006","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00530/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR500006/2023-03-24"},"date":{"value":"2023-03-24"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["-179145T","T179244-"]}}},{"name":"OR499978","node_attrs":{"div":8,"accession":"OR499978","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00521/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499978/2023-05-09"},"date":{"value":"2023-05-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C14016T","C134847T","-179145T","T179244-","C183799T"],"OPG025":["E418K"],"OPG210":["S815L"]},"labels":{"aa":"OPG025: E418K; OPG210: S815L"}}},{"name":"OR499972","node_attrs":{"div":7,"accession":"OR499972","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00515/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499972/2023-04-25"},"date":{"value":"2023-04-25"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G18919A","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","G187517A"]}}},{"name":"NODE_0000256","node_attrs":{"div":6,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","G115293A"],"OPG133":["A135V"]},"labels":{"aa":"OPG133: A135V"}},"children":[{"name":"OR499966","node_attrs":{"div":6,"accession":"OR499966","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00509/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499966/2023-03-31"},"date":{"value":"2023-03-31"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499965","node_attrs":{"div":6,"accession":"OR499965","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00508/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499965/2023-04-10"},"date":{"value":"2023-04-10"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C193406A"]}}},{"name":"OR499964","node_attrs":{"div":6,"accession":"OR499964","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00507/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499964/2023-04-10"},"date":{"value":"2023-04-10"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000257","node_attrs":{"div":6,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G146690A"],"OPG170":["S30F"]},"labels":{"aa":"OPG170: S30F"}},"children":[{"name":"OR499983","node_attrs":{"div":6,"accession":"OR499983","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00526/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499983/2023-06-09"},"date":{"value":"2023-06-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499951","node_attrs":{"div":6,"accession":"OR499951","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00494/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499951/2023-04-30"},"date":{"value":"2023-04-30"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G196724-","A196725-","G196726-"]}}},{"name":"OR499949","node_attrs":{"div":6,"accession":"OR499949","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00492/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499949/2023-03-30"},"date":{"value":"2023-03-30"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A196713-","T196714-","A196715-"]}}},{"name":"NODE_0000258","node_attrs":{"div":8,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-602T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C159608T","G163900-","A163901-","A163902-","T163903-","C163904-","A163905-","G168964A","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A192393C","G192396A","A192402G","-196610A"],"OPG185":["S231F"],"OPG189":["E190-","S191-"]},"labels":{"aa":"OPG185: S231F; OPG189: E190-, S191-"}},"children":[{"name":"OR665165","node_attrs":{"div":9,"accession":"OR665165","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-097301/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR665165/2023-09-XX"},"date":{"value":"2023-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G177918A"],"OPG205":["D755N"]},"labels":{"aa":"OPG205: D755N"}}},{"name":"OR665162","node_attrs":{"div":8,"accession":"OR665162","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-097833/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR665162/2023-09-XX"},"date":{"value":"2023-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000259","node_attrs":{"div":9,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G141131A"]}},"children":[{"name":"OR665164","node_attrs":{"div":9,"accession":"OR665164","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-098659/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR665164/2023-09-XX"},"date":{"value":"2023-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR665163","node_attrs":{"div":10,"accession":"OR665163","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-097798/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR665163/2023-09-XX"},"date":{"value":"2023-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A80466G"],"OPG103":["N156D"]},"labels":{"aa":"OPG103: N156D"}}}]}]}]},{"name":"NODE_0000260","node_attrs":{"div":10,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C15718T","C22349T","C83753T","G98119A","C113363T"],"OPG037":["E29K"],"OPG117":["E691K"],"OPG132":["D60N"]},"labels":{"aa":"OPG037: E29K; OPG117: E691K; OPG132: D60N"}},"children":[{"name":"OR643712","node_attrs":{"div":11,"accession":"OR643712","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00556/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643712/2023-07-31"},"date":{"value":"2023-07-31"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G36246A"]}}},{"name":"OR499987","node_attrs":{"div":10,"accession":"OR499987","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00531/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499987/2023-06-30"},"date":{"value":"2023-06-30"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499975","node_attrs":{"div":10,"accession":"OR499975","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00518/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499975/2023-06-21"},"date":{"value":"2023-06-21"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR473614","node_attrs":{"div":11,"accession":"OR473614","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0077/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR473614/2023-06-27"},"date":{"value":"2023-06-27"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G164230A"],"OPG189":["E300K"]},"labels":{"aa":"OPG189: E300K"}}},{"name":"NODE_0000261","node_attrs":{"div":12,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C23353T","G119341A"],"OPG039":["D256N"],"OPG136":["R83C"]},"labels":{"aa":"OPG039: D256N; OPG136: R83C"}},"children":[{"name":"OR725694","node_attrs":{"div":12,"accession":"OR725694","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0101/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR725694/2023-08-23"},"date":{"value":"2023-08-23"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499995","node_attrs":{"div":12,"accession":"OR499995","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00539/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499995/2023-07-23"},"date":{"value":"2023-07-23"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}}]},{"name":"NODE_0000262","node_attrs":{"div":13,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C11710T","G41336A","G155611A","T179078-","A179079-","T179080-","A179081-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-"]}},"children":[{"name":"OR643703","node_attrs":{"div":13,"accession":"OR643703","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00561/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643703/2023-08-09"},"date":{"value":"2023-08-09"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C179082-","C179091-","C179100-","C179109-","C179118-","C179127-","C179136-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"NODE_0000263","node_attrs":{"div":15,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C629-","C630-","A631-","A632-","G633-","A634-","G635-","A636-","G25213A","C168713T","-179078T","-179079A","-179080T","-179081A","-179083A","-179084T","-179085T","-179086A","-179087T","-179088A","-179089T","-179090A","-179092A","-179093T","-179094T","-179095A","-179096T","-179097A","-179098T","-179099A","-179101A","-179102T","-179103T","-179104A","-179105T","-179106A","-179107T","-179108A","-179110A","-179111T","-179112T","-179113A","-179114T","-179115A","-179116T","-179117A","-179119A","-179120T","-179121T","-179122A","-179123T","-179124A","-179125T","-179126A","-179128A","-179129T","-179130T","-179131A","-179132T","-179133A","-179134T","-179135A","-179137A","-179138T","-179139T","-179140A","-179141T","-179142A","-179143T","-179144A","-196610A","-196611A","-196612A","-196613A","-196614A"],"OPG040":["S89F"],"OPG195":["Q162*"]},"labels":{"aa":"OPG040: S89F; OPG195: Q162*"}},"children":[{"name":"OR643710","node_attrs":{"div":16,"accession":"OR643710","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00564/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643710/2023-08-14"},"date":{"value":"2023-08-14"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","C170130T"]}}},{"name":"OR643704","node_attrs":{"div":15,"accession":"OR643704","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00562/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643704/2023-08-07"},"date":{"value":"2023-08-07"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]}]}]},{"name":"NODE_0000264","node_attrs":{"div":6,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T164946C"]}},"children":[{"name":"OR160416","node_attrs":{"div":10,"accession":"OR160416","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0058/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR160416/2023-05-17"},"date":{"value":"2023-05-17"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G7637A","G36409A","C101983T","G186105A"],"OPG019":["D20N"],"OPG121":["S65L"],"OPG210":["E1584K"]},"labels":{"aa":"OPG019: D20N; OPG121: S65L; OPG210: E1584K"}}},{"name":"NODE_0000265","node_attrs":{"div":7,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C20453T"]}},"children":[{"name":"OR449306","node_attrs":{"div":7,"accession":"OR449306","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/RKI1020"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR449306/2023-07-XX"},"date":{"value":"2023-07-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-602T","-603T","-604T","-605T","-606T","-179145C","-179146A","-179147T","-179148T","-179149A","-179150T","-179151A","-179152T","-179153A","-179154C","-179155A","-179156T","-179157T","-179158A","-179159T","-179160A","-179161T","-179162A","-179163C","-179164A","-179165T","-179166T","-179167A","-179168T","-179169A","-179170T","-179171A"]}}},{"name":"OR421477","node_attrs":{"div":7,"accession":"OR421477","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0019/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR421477/2023-04-20"},"date":{"value":"2023-04-20"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR257451","node_attrs":{"div":7,"accession":"OR257451","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0061/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR257451/2023-05-31"},"date":{"value":"2023-05-31"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR160417","node_attrs":{"div":9,"accession":"OR160417","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0059/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR160417/2023-05-23"},"date":{"value":"2023-05-23"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G43661A","C57550T","A136552-","T136553-","C136554-"],"OPG063":["L10F"],"OPG153":["D385-"]},"labels":{"aa":"OPG063: L10F; OPG153: D385-"}}},{"name":"OR574872","node_attrs":{"div":7,"accession":"OR574872","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0097/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR574872/2023-08-15"},"date":{"value":"2023-08-15"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR643699","node_attrs":{"div":8,"accession":"OR643699","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00550/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643699/2023-07-28"},"date":{"value":"2023-07-28"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G3804T","C193406A"]}}},{"name":"OR574871","node_attrs":{"div":8,"accession":"OR574871","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0096/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR574871/2023-08-10"},"date":{"value":"2023-08-10"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C25865T"]}}},{"name":"OR574862","node_attrs":{"div":7,"accession":"OR574862","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0053/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR574862/2023-05-15"},"date":{"value":"2023-05-15"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR574865","node_attrs":{"div":7,"accession":"OR574865","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0065/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR574865/2023-06-01"},"date":{"value":"2023-06-01"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C169399T"]}}},{"name":"OR574860","node_attrs":{"div":7,"accession":"OR574860","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0051/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR574860/2023-05-12"},"date":{"value":"2023-05-12"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-"],"OPG153":["D385-"]},"labels":{"aa":"OPG153: D385-"}}},{"name":"OR574861","node_attrs":{"div":7,"accession":"OR574861","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0052/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR574861/2023-05-13"},"date":{"value":"2023-05-13"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR574870","node_attrs":{"div":12,"accession":"OR574870","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0095/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR574870/2023-08-03"},"date":{"value":"2023-08-03"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G17038A","G34502A","C86402T","G105411A","A136549-","T136550-","C136551-","A136552-","T136553-","C136554-","C177946T"],"OPG029":["S11F"],"OPG108":["E220K"],"OPG153":["D384-","D385-"],"OPG205":["T764I"]},"labels":{"aa":"OPG029: S11F; OPG108: E220K; OPG153: D384-, D385-; OPG205: T764I"}}},{"name":"OR499999","node_attrs":{"div":7,"accession":"OR499999","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00543/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499999/2023-06-24"},"date":{"value":"2023-06-24"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR500000","node_attrs":{"div":7,"accession":"OR500000","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00544/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR500000/2023-06-28"},"date":{"value":"2023-06-28"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-"]}}},{"name":"OR500005","node_attrs":{"div":8,"accession":"OR500005","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00549/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR500005/2023-07-26"},"date":{"value":"2023-07-26"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T834-","T835-","C836-","G18504A","G174531-","A174532-","T174533-","G174534-","A174535-","A174536-","-179145T","T179244-"]}}},{"name":"OR499955","node_attrs":{"div":7,"accession":"OR499955","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00498/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499955/2023-04-24"},"date":{"value":"2023-04-24"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499954","node_attrs":{"div":7,"accession":"OR499954","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00497/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499954/2023-04-28"},"date":{"value":"2023-04-28"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499958","node_attrs":{"div":10,"accession":"OR499958","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00501/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499958/2023-05-02"},"date":{"value":"2023-05-02"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["A11160G","T126985C","T130733C"],"OPG023":["F581L"],"OPG151":["C604R"]},"labels":{"aa":"OPG023: F581L; OPG151: C604R"}}},{"name":"OR499952","node_attrs":{"div":7,"accession":"OR499952","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00495/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499952/2023-04-26"},"date":{"value":"2023-04-26"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR473618","node_attrs":{"div":8,"accession":"OR473618","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0087/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR473618/2023-07-12"},"date":{"value":"2023-07-12"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C69779T","C196709-","A196710-","A196711-"],"OPG088":["E29K"]},"labels":{"aa":"OPG088: E29K"}}},{"name":"OR473615","node_attrs":{"div":7,"accession":"OR473615","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0083/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR473615/2023-07-10"},"date":{"value":"2023-07-10"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR421479","node_attrs":{"div":7,"accession":"OR421479","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0022/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR421479/2023-05-04"},"date":{"value":"2023-05-04"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR160415","node_attrs":{"div":7,"accession":"OR160415","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0057/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Meical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR160415/2023-05-18"},"date":{"value":"2023-05-18"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR421480","node_attrs":{"div":7,"accession":"OR421480","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0023/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR421480/2023-05-07"},"date":{"value":"2023-05-07"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR421478","node_attrs":{"div":7,"accession":"OR421478","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0020/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR421478/2023-04-27"},"date":{"value":"2023-04-27"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000266","node_attrs":{"div":8,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C2313T","G194897A"],"OPG002":["D147N"],"OPG002_dup":["D147N"]},"labels":{"aa":"OPG002: D147N; OPG002_dup: D147N"}},"children":[{"name":"OR500001","node_attrs":{"div":8,"accession":"OR500001","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00545/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR500001/2023-06-10"},"date":{"value":"2023-06-10"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR499998","node_attrs":{"div":9,"accession":"OR499998","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Human/USA/CA-LACPHL-MA00542/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR499998/2023-06-22"},"date":{"value":"2023-06-22"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G51378A","T196676-","G196677-","T196678-"]}}}]},{"name":"NODE_0000270","node_attrs":{"div":8,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C180618T"],"OPG209":["S34L"]},"labels":{"aa":"OPG209: S34L"}},"children":[{"name":"OR421481","node_attrs":{"div":9,"accession":"OR421481","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0067/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR421481/2023-06-08"},"date":{"value":"2023-06-08"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C98128T"],"OPG117":["P694S"]},"labels":{"aa":"OPG117: P694S"}}},{"name":"OR353590","node_attrs":{"div":9,"accession":"OR353590","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MN-MDH-MPXV_0080"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Minnesota Department of Health, Public Health Laboratory"},"strain_display":{"value":"USA/OR353590/2023-06-05"},"date":{"value":"2023-06-05"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C134847T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T194619C"],"OPG002_dup":["F54S"]},"labels":{"aa":"OPG002_dup: F54S"}}},{"name":"OR473622","node_attrs":{"div":8,"accession":"OR473622","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0076/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR473622/2023-06-27"},"date":{"value":"2023-06-27"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR473620","node_attrs":{"div":8,"accession":"OR473620","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-04-0074/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR473620/2023-06-22"},"date":{"value":"2023-06-22"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR473619","node_attrs":{"div":10,"accession":"OR473619","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0088/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR473619/2023-07-17"},"date":{"value":"2023-07-17"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C61724T","C111728T"],"OPG080":["E99K"],"OPG130":["D59N"]},"labels":{"aa":"OPG080: E99K; OPG130: D59N"}}},{"name":"NODE_0000271","node_attrs":{"div":9,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-604T","-605T","-606T","C174050T"]}},"children":[{"name":"OR725692","node_attrs":{"div":9,"accession":"OR725692","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0098/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR725692/2023-08-19"},"date":{"value":"2023-08-19"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G635-","A636-","A637-"]}}},{"name":"OR502626","node_attrs":{"div":13,"accession":"OR502626","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0091/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR502626/2023-07-23"},"date":{"value":"2023-07-23"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C5912T","C25865T","C56140T","C175358T","G191298A"],"OPG015":["R82K"],"OPG015_dup":["R82K"],"OPG074":["R329K"],"OPG204":["S276L"]},"labels":{"aa":"OPG015: R82K; OPG015_dup: R82K; OPG074: R329K; OPG204: S276L"}}},{"name":"OR473617","node_attrs":{"div":9,"accession":"OR473617","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-MPXV-050-0085/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR473617/2023-07-11"},"date":{"value":"2023-07-11"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000272","node_attrs":{"div":11,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T765-","T766-","C767-","G113508A","C136791T"],"OPG153":["E293K"]},"labels":{"aa":"OPG153: E293K"}},"children":[{"name":"OR725697","node_attrs":{"div":11,"accession":"OR725697","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0107/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR725697/2023-09-06"},"date":{"value":"2023-09-06"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR725696","node_attrs":{"div":11,"accession":"OR725696","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0106/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR725696/2023-09-05"},"date":{"value":"2023-09-05"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000273","node_attrs":{"div":10,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C105798T"]}},"children":[{"name":"OR502625","node_attrs":{"div":10,"accession":"OR502625","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0090/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR502625/2023-07-21"},"date":{"value":"2023-07-21"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000274","node_attrs":{"div":11,"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G148126A","T196633-","C196634-","T196635-"]}},"children":[{"name":"OR725698","node_attrs":{"div":11,"accession":"OR725698","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-052-0100/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR725698/2023-08-22"},"date":{"value":"2023-08-22"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}},{"name":"OR725693","node_attrs":{"div":11,"accession":"OR725693","author":{"author":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S.","value":"Green,S.,Kunstman,K.,Barbian,H.,Araujo Perez,F.,Kittner,A.,Bobrovska,S."},"lineage":{"value":"B.1.20"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/USA/IL-RIPHL-050-0099/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Rush University Medical Center, Regional Innovative Public Health Laboratory (RIPHL)"},"strain_display":{"value":"USA/OR725693/2023-08-18"},"date":{"value":"2023-08-18"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{}}}]}]}]}]}]}]}]}]}]}]},{"name":"NODE_0000275","node_attrs":{"div":1,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G190660A"],"OPG016":["R84K"]},"labels":{"aa":"OPG016: R84K","clade":"B.1.3"}},"children":[{"name":"ON983168","node_attrs":{"div":1,"accession":"ON983168","author":{"author":"Chmel,M.,Pajer,P.,Nagy,A.,Zlamal,M.,Jirincova,H.,Dresler,J.,Bartos,O.","value":"Chmel,M.,Pajer,P.,Nagy,A.,Zlamal,M.,Jirincova,H.,Dresler,J.,Bartos,O."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPxV/Prague_001/2022/flye_medaka"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Military Heatlh Institute, Military Heatlh Institute in Prague"},"strain_display":{"value":"Czech Republic/ON983168/2022-04-28"},"date":{"value":"2022-04-28"},"country":{"value":"Czech Republic"}},"branch_attrs":{"mutations":{"nuc":["T80849-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}}},{"name":"OP414383","node_attrs":{"div":1,"accession":"OP414383","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0356/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP414383/2022-05-23"},"date":{"value":"2022-05-23"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["A666-","T667-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G"]}}},{"name":"OQ721953","node_attrs":{"div":9,"accession":"OQ721953","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Taiwan/110-525030/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"strain_display":{"value":"Taiwan/OQ721953/2023-03-XX"},"date":{"value":"2023-03-XX"},"country":{"value":"Taiwan"}},"branch_attrs":{"mutations":{"nuc":["T605-","T606-","C64426T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C166940T","T177665A","A177666T","A177667T","G178104T","G178290T","T178629A","G196412A"],"OPG205":["N670K","N671F"]},"labels":{"aa":"OPG205: N670K, N671F"}}},{"name":"NODE_0000276","node_attrs":{"div":6,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C17196T","C39898T","C148933T","G171318A","C175241T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"],"OPG057":["D100N"],"OPG174":["E155K"],"OPG199":["E111K"],"OPG204":["S237L"]},"labels":{"aa":"OPG057: D100N; OPG174: E155K; OPG199: E111K; OPG204: S237L"}},"children":[{"name":"OP205116","node_attrs":{"div":6,"accession":"OP205116","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000158"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205116/2022-07-07"},"date":{"value":"2022-07-07"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{}}},{"name":"OP536780","node_attrs":{"div":6,"accession":"OP536780","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000404"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536780/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T606-","A62041-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"]}}}]},{"name":"NODE_0000277","node_attrs":{"div":2,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G55133A"],"OPG074":["R665C"]},"labels":{"aa":"OPG074: R665C"}},"children":[{"name":"OQ581854","node_attrs":{"div":4,"accession":"OQ581854","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Taiwan/109-005210/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"strain_display":{"value":"Taiwan/OQ581854/2023-02-XX"},"date":{"value":"2023-02-XX"},"country":{"value":"Taiwan"}},"branch_attrs":{"mutations":{"nuc":["G152776A","G158406A","A192404-","G192405-","T192406-","A192411-"],"OPG180":["D29N"]},"labels":{"aa":"OPG180: D29N"}}},{"name":"NODE_0000278","node_attrs":{"div":3,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C64426T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"ON792320","node_attrs":{"div":4,"accession":"ON792320","author":{"author":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A.","value":"Kufner,V.,Ziltener,G.,Zaheri,M.,Schmutz,S.,Audige,A.,Bernasconi,O.,Steiner,K.,Huder,J.,Shah,C.,Capaul,R.,Bloemberg,G.,Boeni,J.,Huber,M.,Trkola,A."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Switzerland/ZH-UZH-IMV-3ba6449f/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University of Zurich, Institute of Medical Virology"},"strain_display":{"value":"Switzerland/ON792320/2022-06-01"},"date":{"value":"2022-06-01"},"country":{"value":"Switzerland"}},"branch_attrs":{"mutations":{"nuc":["G159376A"],"OPG185":["D154N"]},"labels":{"aa":"OPG185: D154N"}}},{"name":"ON782054","node_attrs":{"div":5,"accession":"ON782054","author":{"author":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0001a/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"strain_display":{"value":"Spain/ON782054/2022-05-31"},"date":{"value":"2022-05-31"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["G50337A","A122238T","-133177T","-133178C","-133179T","-133180T","-133181T","-133182C","-133183T","-133184C","-133185A","-133186A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A169759G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A193392G","T193688C","T194099C","T194619C","T195948C","-196615A"],"OPG001_dup":["L105S"],"OPG002_dup":["F54S"],"OPG003_dup":["N264D"],"OPG069":["G118R"],"OPG143":["S360T"]},"labels":{"aa":"OPG001_dup: L105S; OPG002_dup: F54S; OPG003_dup: N264D; OPG069: G118R; OPG143: S360T"}}},{"name":"ON782055","node_attrs":{"div":5,"accession":"ON782055","author":{"author":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C.","value":"Alcoba-Florez,J.,Munoz-Barrera,A.,Ciuffreda,L.,Rodriguez-Perez,H.,Rubio-Rodriguez,L.A.,Gil-Campesino,H.,Garcia-Martinez de Artola,D.,Inigo-Campos,A.,Diez-Gil,O.,Gonzalez-Montelongo,R.,Valenzuela-Fernandez,A.,Lorenzo-Salazar,J.M.,Flores,C."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Spain/HUNSC_ITER_0001b/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Instituto Tecnologico y de Energias Renovables (ITER), Genomics Division"},"strain_display":{"value":"Spain/ON782055/2022-05-31"},"date":{"value":"2022-05-31"},"country":{"value":"Spain"}},"branch_attrs":{"mutations":{"nuc":["A48265T","C48296G","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG068":["D22V"]},"labels":{"aa":"OPG068: D22V"}}},{"name":"ON782021","node_attrs":{"div":3,"accession":"ON782021","author":{"author":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O.","value":"Kant,R.,Smura,T.,Vauhkonen,H.,Vapalahti,O."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX-37/Finland/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"University of Helsinki, Department of Virology, Faculty of Medicine"},"strain_display":{"value":"Finland/ON782021/2022-05-24"},"date":{"value":"2022-05-24"},"country":{"value":"Finland"}},"branch_attrs":{"mutations":{"nuc":["-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"ON622722","node_attrs":{"div":4,"accession":"ON622722","lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_FR_HCL0001_2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Virology, GENomique EPIdemiologique das maladies Infectieuses, France"},"strain_display":{"value":"France/ON622722/2022-05-22"},"date":{"value":"2022-05-22"},"country":{"value":"France"}},"branch_attrs":{"mutations":{"nuc":["C109627A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","A179077-","T179078-","A179079-","T179080-","A179081-","C179082-","A179083-","T179084-","T179085-","A179086-","T179087-","A179088-","T179089-","A179090-","C179091-","A179092-","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG129":["A460S"]},"labels":{"aa":"OPG129: A460S"}}},{"name":"OP215273","node_attrs":{"div":5,"accession":"OP215273","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Uddin,S.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2022/RKI251"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OP215273/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["G5515A","T54004C","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C179259T","C191695T"]}}},{"name":"OP205067","node_attrs":{"div":3,"accession":"OP205067","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_UK_2022_9000061"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP205067/2022-05-27"},"date":{"value":"2022-05-27"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["-607T","-196615A"]}}},{"name":"OP415255","node_attrs":{"div":3,"accession":"OP415255","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPX_GZUtx9_9000301"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP415255/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T606-","A196614-"]}}},{"name":"OP536751","node_attrs":{"div":4,"accession":"OP536751","author":{"author":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M.","value":"Groves,N.,Osman,K.L.,Lewandowski,K.S.,Carter,D.P.,Pullan,S.T.,Myers,R.,Vipond,R.,Chand,M."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"9000370"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"UKHSA, Research and Evaluation"},"strain_display":{"value":"United Kingdom/OP536751/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"United Kingdom"}},"branch_attrs":{"mutations":{"nuc":["T606-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C158422T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"]}}},{"name":"OP605568","node_attrs":{"div":6,"accession":"OP605568","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-26-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605568/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["C12426T","C44716T","C141194T","A196614-"],"OPG023":["E159K"],"OPG064":["E395K"]},"labels":{"aa":"OPG023: E159K; OPG064: E395K"}}},{"name":"OP555633","node_attrs":{"div":4,"accession":"OP555633","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0562/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OP555633/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["A136552-","T136553-","C136554-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C168066T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG153":["D385-"],"OPG193":["Q245*"]},"labels":{"aa":"OPG153: D385-; OPG193: Q245*"}}},{"name":"OQ054224","node_attrs":{"div":4,"accession":"OQ054224","author":{"author":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y.","value":"Gigante,C.,Ghinai,I.,Zhao,H.,Batra,D.,Hetrick,E.,Howard,D.,Kovar,L.,Seabolt,M.,Morrison,S.,Desch,M.,Knipe,K.,Weigand,M.,Sheth,M.,Burgin,A.,Burroughs,M.,Lee,J.,Wilkins,K.,McCollum,A.,Hutson,C.,Davidson,W.,Rao,A.,Kerins,J.,Li,Y."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_USA_2022_IL0030"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"CDC, DHCPP-PRB"},"strain_display":{"value":"USA/OQ054224/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G108819A","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OR035732","node_attrs":{"div":4,"accession":"OR035732","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_126"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035732/2022-10-03"},"date":{"value":"2022-10-03"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["G92135A","T133102-","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OR353547","node_attrs":{"div":3,"accession":"OR353547","author":{"author":"Plumb,M.R.","value":"Plumb,M.R."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MN-MDH-MPXV_0037"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Minnesota Department of Health, Public Health Laboratory"},"strain_display":{"value":"USA/OR353547/2022-08-03"},"date":{"value":"2022-08-03"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G150560-","A150561-","T150562-","A150563-","T150564-","G150565-","A150566-","T150567-","G150568-","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OR134560","node_attrs":{"div":14,"accession":"OR134560","author":{"author":"Miller,H.,Bajwa,M.","value":"Miller,H.,Bajwa,M."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"B1221136"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Delaware Public Health Lab, Sequencing/Bioinformatics"},"strain_display":{"value":"USA/OR134560/2023-03-13"},"date":{"value":"2023-03-13"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["C19558T","G32277A","C35688T","G39140A","G55059A","G75512A","C110402T","C121161T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C170673T","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C179542T","C189174T"],"OPG034":["E150K"],"OPG049":["S292L"],"OPG073":["S28L"],"OPG095":["R237K"],"OPG139":["A70T"]},"labels":{"aa":"OPG034: E150K; OPG049: S292L; OPG073: S28L; OPG095: R237K; OPG139: A70T"}}},{"name":"OX248696","node_attrs":{"div":5,"accession":"OX248696","lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"RNA"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Science Park of Comenius University of Bratislava, Ilkovicova 8, 841 04 Bratislava"},"strain_display":{"value":"Slovakia/OX248696/2022-07-04"},"date":{"value":"2022-07-04"},"country":{"value":"Slovakia"}},"branch_attrs":{"mutations":{"nuc":["T606-","G37250A","C138080T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","A196614-"],"OPG155":["E138K"]},"labels":{"aa":"OPG155: E138K"}}},{"name":"OR759179","node_attrs":{"div":5,"accession":"OR759179","author":{"author":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A.","value":"Isabel,S.,Eshaghi,A.,Duvvuri,V.R.,Gubbay,J.B.,Cronin,K.,Li,A.,Hasso,M.,Clark,S.T.,Hopkins,J.P.,Patel,S.N.,Braukmann,T.W.A."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"hMpxV/Canada/ON-PHOL091/2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Public Health Ontario, Microbiology and Laboratory Science"},"strain_display":{"value":"Canada/OR759179/2022-09-01"},"date":{"value":"2022-09-01"},"country":{"value":"Canada"}},"branch_attrs":{"mutations":{"nuc":["G85581A","C122502T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG107":["V24I"],"OPG143":["D272N"]},"labels":{"aa":"OPG107: V24I; OPG143: D272N"}}},{"name":"ON754985","node_attrs":{"div":3,"accession":"ON754985","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_SI2022_S4"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/ON754985/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["A33-","T157-","-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"OP605552","node_attrs":{"div":3,"accession":"OP605552","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-09-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605552/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["T38-","T157-","-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"ON754986","node_attrs":{"div":3,"accession":"ON754986","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_SI2022_S5"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/ON754986/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["A161-","-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"ON754984","node_attrs":{"div":3,"accession":"ON754984","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_SI2022_S3"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/ON754984/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["A240-","-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"ON838178","node_attrs":{"div":3,"accession":"ON838178","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"SI2022_S7"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/ON838178/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["A33-","T157-","-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","A196614-"]}}},{"name":"OP605551","node_attrs":{"div":3,"accession":"OP605551","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-08-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605551/2022-06-XX"},"date":{"value":"2022-06-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["A33-","T157-","-607T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"]}}},{"name":"NODE_0000279","node_attrs":{"div":4,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["A33-","T157-","-607T","G167517A","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T"],"OPG193":["E62K"]},"labels":{"aa":"OPG193: E62K"}},"children":[{"name":"ON754987","node_attrs":{"div":4,"accession":"ON754987","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV_SI2022_S1_VEROE6"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/ON754987/2022-05-23"},"date":{"value":"2022-05-23"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{}}},{"name":"ON609725","node_attrs":{"div":4,"accession":"ON609725","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Skubic,C.,Rozman,D.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Skubic,C.,Rozman,D.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"SLO"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Laboratory for Diagnostics of Zoonoses & WHO Centre, Institute of Microbiology & Immunology, Faculty of Medicine, University of Ljubljana, Slovenia"},"strain_display":{"value":"Slovenia/ON609725/2022-05-23"},"date":{"value":"2022-05-23"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000280","node_attrs":{"div":8,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T594A","-607T","-608T","-609T","G72609A","G72610T","G72611T","T72614A","A72617C","A72977-","A72978-","T72979-","G72980-","A72981-"],"OPG092":["C111G","K112*","P113N","T114S"]},"labels":{"aa":"OPG092: C111G, K112*, P113N, T114S"}},"children":[{"name":"OP605560","node_attrs":{"div":12,"accession":"OP605560","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-18-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605560/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["G19153A","A55133G","T64426C","G183650A"],"OPG074":["C665R"],"OPG210":["M765I"]},"labels":{"aa":"OPG074: C665R; OPG210: M765I"}}},{"name":"OP605562","node_attrs":{"div":9,"accession":"OP605562","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-20-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605562/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["A29748T"],"OPG047":["*483K"]},"labels":{"aa":"OPG047: *483K"}}}]},{"name":"NODE_0000281","node_attrs":{"div":15,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C15969T","C17998T","G40610A","C43803T","C63879T","G70190A","G118289A","C147011T","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","G152776A","C159532T","G161629A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","C189427T"],"OPG005":["P77S"],"OPG027":["E137K"],"OPG031":["M277I"],"OPG064":["G699E"],"OPG083":["D280N"],"OPG089":["E109K"],"OPG180":["D29N"],"OPG185":["P206S"],"OPG188":["E12K"]},"labels":{"aa":"OPG005: P77S; OPG027: E137K; OPG031: M277I; OPG064: G699E; OPG083: D280N; OPG089: E109K; OPG180: D29N; OPG185: P206S; OPG188: E12K"}},"children":[{"name":"OQ451904","node_attrs":{"div":15,"accession":"OQ451904","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/RKI719"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ451904/2023-01-XX"},"date":{"value":"2023-01-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"OQ451903","node_attrs":{"div":15,"accession":"OQ451903","author":{"author":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Pape,K.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/RKI718"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OQ451903/2023-01-XX"},"date":{"value":"2023-01-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000282","node_attrs":{"div":6,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["-607T","C8612T","C56018T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","G187156A"],"OPG074":["E370K"]},"labels":{"aa":"OPG074: E370K"}},"children":[{"name":"OP605570","node_attrs":{"div":6,"accession":"OP605570","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-28-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605570/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000283","node_attrs":{"div":7,"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G52232A"],"OPG071":["S736L"]},"labels":{"aa":"OPG071: S736L"}},"children":[{"name":"OP605585","node_attrs":{"div":7,"accession":"OP605585","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-44-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605585/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{}}},{"name":"OP605581","node_attrs":{"div":7,"accession":"OP605581","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-40-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605581/2022-08-XX"},"date":{"value":"2022-08-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["A204-"]}}},{"name":"OP605578","node_attrs":{"div":10,"accession":"OP605578","author":{"author":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T.","value":"Zakotnik,S.,Vlaj,D.,Suljic,A.,Zorec,T.M.,Korva,M.,Poljak,M.,Avsic Zupanc,T."},"lineage":{"value":"B.1.3"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Slovenia-MPXV-36-2022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Laboratory for Diagnostics of Zoonoses and WHO Centre"},"strain_display":{"value":"Slovenia/OP605578/2022-07-XX"},"date":{"value":"2022-07-XX"},"country":{"value":"Slovenia"}},"branch_attrs":{"mutations":{"nuc":["T163-","C64583A","C115217T","C183631T"],"OPG083":["G45V"],"OPG210":["S759F"]},"labels":{"aa":"OPG083: G45V; OPG210: S759F"}}}]}]},{"name":"NODE_0000289","node_attrs":{"div":4,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G105923A","-150586A","-150587T","-150588A","-150589T","-150590G","-150591A","-150592T","-150593G","-150594G","-150595A","-150596T","-150597A","-150598T","-150599G","-150600A","-150601T","-150602G","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","C179181-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","C179226-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG124":["L16F"]},"labels":{"aa":"OPG124: L16F","clade":"C.1"}},"children":[{"name":"LC753969","node_attrs":{"div":4,"accession":"LC753969","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220176"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC753969/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{}}},{"name":"OR035728","node_attrs":{"div":5,"accession":"OR035728","author":{"author":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P.","value":"Wawina-Bokalanga,T.,Vanmechelen,B.,Logist,A.-S.,Ysebaert,L.,Verlinden,J.,Horemans,M.,Van Holm,B.,Bloemen,M.,Maes,P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/UZ_REGA_122"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"KU Leuven, Microbiology, Immunology and Transplantation"},"strain_display":{"value":"Belgium/OR035728/2022-10-28"},"date":{"value":"2022-10-28"},"country":{"value":"Belgium"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G149818A","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","T196712-","A196713-","T196714-"],"OPG176":["D4N"]},"labels":{"aa":"OPG176: D4N"}}},{"name":"OQ581853","node_attrs":{"div":6,"accession":"OQ581853","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Taiwan/110-093831/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"strain_display":{"value":"Taiwan/OQ581853/2023-02-XX"},"date":{"value":"2023-02-XX"},"country":{"value":"Taiwan"}},"branch_attrs":{"mutations":{"nuc":["T132513C","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","C185069T"]}}},{"name":"LC753970","node_attrs":{"div":4,"accession":"LC753970","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220187"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC753970/2022-10-XX"},"date":{"value":"2022-10-XX"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{}}},{"name":"LC753968","node_attrs":{"div":4,"accession":"LC753968","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2022/TKY220165"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC753968/2022-09-XX"},"date":{"value":"2022-09-XX"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000291","node_attrs":{"div":5,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C3987T"]}},"children":[{"name":"OQ721954","node_attrs":{"div":10,"accession":"OQ721954","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Taiwan/110-539498/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"strain_display":{"value":"Taiwan/OQ721954/2023-03-XX"},"date":{"value":"2023-03-XX"},"country":{"value":"Taiwan"}},"branch_attrs":{"mutations":{"nuc":["-607T","C798T","C11923T","T14737C","C48442T","G90825A","G102694A","T179093-","T179094-","A179095-","T179096-","A179097-","T179098-","A179099-","C179100-","A179101-","T179102-","T179103-","A179104-","T179105-","A179106-","T179107-","A179108-","C179109-","A179110-","T179111-","T179112-","A179113-","T179114-","A179115-","T179116-","A179117-","C179118-","A179119-","T179120-","T179121-","A179122-","T179123-","A179124-","T179125-","A179126-","C179127-","A179128-","T179129-","T179130-","A179131-","T179132-","A179133-","T179134-","A179135-","C179136-","A179137-","T179138-","T179139-","A179140-","T179141-","A179142-","T179143-","A179144-","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","-179176A","-179177T","-179178A","-179179T","-179180A","-179181C","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179226C","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A","A191312G","G196412A"],"OPG015_dup":["I87V"],"OPG068":["A81V"]},"labels":{"aa":"OPG015_dup: I87V; OPG068: A81V"}}},{"name":"OQ581855","node_attrs":{"div":8,"accession":"OQ581855","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Taiwan/0310000009/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"strain_display":{"value":"Taiwan/OQ581855/2023-03-XX"},"date":{"value":"2023-03-XX"},"country":{"value":"Taiwan"}},"branch_attrs":{"mutations":{"nuc":["G15797A","C41168T","A137251T"]}}}]},{"name":"NODE_0000292","node_attrs":{"div":5,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C166940T","G193223A"]}},"children":[{"name":"OQ721952","node_attrs":{"div":12,"accession":"OQ721952","author":{"author":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y.","value":"Lin,J.-H.,Chiu,S.-C.,Huang,H.-I.,Huang,W.-L.,Li,T.-Y.,Fann,W.-B.,Hsieh,P.-Y.,Yang,J.-Y."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Taiwan/240031000030/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Centers for Disease Control, Taiwan, Center of Diagnostics and Vaccine Development"},"strain_display":{"value":"Taiwan/OQ721952/2023-03-XX"},"date":{"value":"2023-03-XX"},"country":{"value":"Taiwan"}},"branch_attrs":{"mutations":{"nuc":["C798T","C13503T","G33539A","G34948A","G40174A","G156025A","A183935G","A184219G"],"OPG025":["A589T"],"OPG054":["A350V"],"OPG057":["P8S"],"OPG210":["I860M","Y955C"]},"labels":{"aa":"OPG025: A589T; OPG054: A350V; OPG057: P8S; OPG210: I860M, Y955C"}}},{"name":"NODE_0000293","node_attrs":{"div":6,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C3987T","-179172C","-179173A","-179174T","-179175T","-179176A","-179177T","-179178A","-179179T","-179180A","-179182A","-179183T","-179184T","-179185A","-179186T","-179187A","-179188T","-179189A","-179190C","-179191A","-179192T","-179193T","-179212A","-179213T","-179214A","-179215T","-179216A","-179217C","-179218A","-179219T","-179220T","-179221A","-179222T","-179223A","-179224T","-179225A","-179227A","-179228T","-179229T","-179230A","-179231T","-179232A","-179233T","-179234A","-179235C","-179236A","-179237T","-179238T","-179239A","-179240T","-179241A","-179242T","-179243A"]}},"children":[{"name":"LC760460","node_attrs":{"div":8,"accession":"LC760460","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220304"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC760460/2023-01-23"},"date":{"value":"2023-01-23"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{"nuc":["G48887A","G75699A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"],"OPG096":["R38Q"]},"labels":{"aa":"OPG096: R38Q"}}},{"name":"LC760461","node_attrs":{"div":7,"accession":"LC760461","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.,Harada,S.,Amano,A."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220343"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC760461/2023-02-13"},"date":{"value":"2023-02-13"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{"nuc":["C798T","C68765T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G196412A"],"OPG086":["M33I"]},"labels":{"aa":"OPG086: M33I"}}},{"name":"LC756924","node_attrs":{"div":7,"accession":"LC756924","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220325"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC756924/2023-01-30"},"date":{"value":"2023-01-30"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{"nuc":["C151434T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"LC756923","node_attrs":{"div":6,"accession":"LC756923","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220318"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC756923/2023-01-25"},"date":{"value":"2023-01-25"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{"nuc":["C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"LC756925","node_attrs":{"div":7,"accession":"LC756925","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220342"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC756925/2023-02-09"},"date":{"value":"2023-02-09"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{"nuc":["C84734T","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OR459782","node_attrs":{"div":8,"accession":"OR459782","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P009-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459782/2023-04-12"},"date":{"value":"2023-04-12"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["G12908A","C159231T","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C"]}}},{"name":"OR665166","node_attrs":{"div":11,"accession":"OR665166","author":{"author":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L.","value":"Sereewit,J.,Xie,H.,Roychoudhury,P.,Greninger,A.L."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MpxV/human/USA/WA-UW-092809/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"UW Virology, Laboratory Medicine"},"strain_display":{"value":"USA/OR665166/2023-09-XX"},"date":{"value":"2023-09-XX"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["T606-","G13434A","G29650A","C33332T","G37974A","C74691T","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179181C","-179226C","A196614-"],"OPG025":["R612C"],"OPG046":["T27I"],"OPG050":["R26Q"],"OPG056":["S354L"]},"labels":{"aa":"OPG025: R612C; OPG046: T27I; OPG050: R26Q; OPG056: S354L"}}},{"name":"OR459804","node_attrs":{"div":7,"accession":"OR459804","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P034-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459804/2023-04-25"},"date":{"value":"2023-04-25"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["T133102-","G163603A","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C"],"OPG189":["D91N"]},"labels":{"aa":"OPG189: D91N"}}},{"name":"OR459798","node_attrs":{"div":7,"accession":"OR459798","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P027-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459798/2023-04-22"},"date":{"value":"2023-04-22"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["G5173A","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","C192037T"]}}},{"name":"OR459797","node_attrs":{"div":6,"accession":"OR459797","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P026-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459797/2023-04-22"},"date":{"value":"2023-04-22"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["A113921-","A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","T169716C","G169717A","T169721A","G169775A","T169776C","A169780T","-179181T","-179226T"],"OPG197":["M16T","S18T","V36T","E37D"]},"labels":{"aa":"OPG197: M16T, S18T, V36T, E37D"}}},{"name":"OR459796","node_attrs":{"div":8,"accession":"OR459796","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P024-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459796/2023-04-21"},"date":{"value":"2023-04-21"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["T606-","G57129A","G144095A","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","A196614-"],"OPG165":["D194N"]},"labels":{"aa":"OPG165: D194N"}}},{"name":"OR459793","node_attrs":{"div":6,"accession":"OR459793","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P020-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459793/2023-04-19"},"date":{"value":"2023-04-19"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C"]}}},{"name":"LC756922","node_attrs":{"div":6,"accession":"LC756922","author":{"author":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K.","value":"Kasuya,F.,Negishi,A.,Kumagai,R.,Hasegawa,M.,Fujiwara,T.,Miyake,H.,Nagashima,M.,Sadamasu,K."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/human/Japan/Tokyo/2023/TKY220310"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Department of Microbiology; 3-24-1,Hyakunin-cho, Shinjuku-ku, Tokyo 169-0073"},"strain_display":{"value":"Japan/LC756922/2023-01-25"},"date":{"value":"2023-01-25"},"country":{"value":"Japan"}},"branch_attrs":{"mutations":{"nuc":["C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-"]}}},{"name":"OR459783","node_attrs":{"div":6,"accession":"OR459783","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P010-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459783/2023-04-13"},"date":{"value":"2023-04-13"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C"]}}},{"name":"NODE_0000294","node_attrs":{"div":7,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T606-","C155209T","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C","A196614-"]}},"children":[{"name":"OR459780","node_attrs":{"div":7,"accession":"OR459780","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P007-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459780/2023-04-10"},"date":{"value":"2023-04-10"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{}}},{"name":"OR459789","node_attrs":{"div":7,"accession":"OR459789","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P016-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459789/2023-04-18"},"date":{"value":"2023-04-18"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000297","node_attrs":{"div":7,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C52108T","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C"]}},"children":[{"name":"OR459784","node_attrs":{"div":8,"accession":"OR459784","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P011-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459784/2023-04-14"},"date":{"value":"2023-04-14"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["C97608T"]}}},{"name":"OR459800","node_attrs":{"div":7,"accession":"OR459800","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P029-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459800/2023-04-23"},"date":{"value":"2023-04-23"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{}}},{"name":"OR459794","node_attrs":{"div":8,"accession":"OR459794","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P021-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459794/2023-04-21"},"date":{"value":"2023-04-21"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["T178915C"]}}},{"name":"OR459802","node_attrs":{"div":7,"accession":"OR459802","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P032-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459802/2023-04-25"},"date":{"value":"2023-04-25"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{}}},{"name":"OR459792","node_attrs":{"div":7,"accession":"OR459792","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P019-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459792/2023-04-19"},"date":{"value":"2023-04-19"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000299","node_attrs":{"div":8,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C149963T","G184562A"],"OPG176":["S52L"]},"labels":{"aa":"OPG176: S52L"}},"children":[{"name":"OR459778","node_attrs":{"div":9,"accession":"OR459778","author":{"author":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C.","value":"Chung,Y.-S.,Yi,H.,Choi,M.-M.,Kim,J.-W.,Lee,M.,Lee,S.,Sim,G.,Lee,J.H.,Shin,H.,Choi,C."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV-ROK-P005-2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Asia"},"institution":{"value":"Korea Disease Control and Prevention Agency, Division of High-risk Pathogens"},"strain_display":{"value":"South Korea/OR459778/2023-03-13"},"date":{"value":"2023-03-13"},"country":{"value":"South Korea"}},"branch_attrs":{"mutations":{"nuc":["G85691A","-179181C","-179194A","-179195T","-179196A","-179197T","-179198A","-179199C","-179200A","-179201T","-179202T","-179203A","-179204T","-179205A","-179206T","-179207A","-179208C","-179209A","-179210T","-179211T","-179226C"]}}},{"name":"NODE_0000300","node_attrs":{"div":13,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C21062T","G101241A","G152866A","C179172-","A179173-","T179174-","T179175-","A179176-","T179177-","A179178-","T179179-","A179180-","A179182-","T179183-","T179184-","A179185-","T179186-","A179187-","T179188-","A179189-","C179190-","A179191-","T179192-","T179193-","A179212-","T179213-","A179214-","T179215-","A179216-","C179217-","A179218-","T179219-","T179220-","A179221-","T179222-","A179223-","T179224-","A179225-","A179227-","T179228-","T179229-","A179230-","T179231-","A179232-","T179233-","A179234-","C179235-","A179236-","T179237-","T179238-","A179239-","T179240-","A179241-","T179242-","A179243-","G188348A","C188946T","C191053-","A191054-","T191055-","G191056-","G191057-","A191058-","G191059-","T191060-","C191061-","G191062-","G191063-","T191064-","A191065-","G191066-","A191067-","T191068-","T191069-","T191070-","C191071-","A191072-","T191073-","G191074-","G191075-","C191076-","T191077-","G191078-","T191079-","C191080-","G191081-","A191082-","T191083-","G191084-","A191085-","G191086-","C191087-","A191088-","G191089-","T191090-","T191091-","T191092-","C191093-","A191094-","C191095-","G191096-","A191097-","C191098-","G191099-","A191100-","C191101-","C191102-","T191103-","C191104-","G191105-","A191106-","T191107-","C191108-","T191109-","T191110-","T191111-","G191112-","G191113-","T191114-","C191115-","A191116-","T191117-","T191118-","A191119-","T191120-","C191121-","T191122-","T191123-","T191124-","G191125-","G191126-","T191127-","A191128-","G191129-"],"OPG036":["M1I"],"OPG180":["D59N"]},"labels":{"aa":"OPG036: M1I; OPG180: D59N"}},"children":[{"name":"OR643705","node_attrs":{"div":21,"accession":"OR643705","author":{"author":"Garrigues,J.M.,Green,N.M.","value":"Garrigues,J.M.,Green,N.M."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPV/Human/USA/CA-LACPHL-MA00563/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"North America"},"institution":{"value":"Los Angeles County Public Health Laboratories"},"strain_display":{"value":"USA/OR643705/2023-08-16"},"date":{"value":"2023-08-16"},"country":{"value":"USA"}},"branch_attrs":{"mutations":{"nuc":["G21880A","G47532A","A101241G","C125074T","G133704A","G133838A","A152866G","C179145-","A179146-","T179147-","T179148-","A179149-","T179150-","A179151-","T179152-","A179153-","C179154-","A179155-","T179156-","T179157-","A179158-","T179159-","A179160-","T179161-","A179162-","C179163-","A179164-","T179165-","T179166-","A179167-","T179168-","A179169-","T179170-","A179171-","T180483A","-191053C","-191054A","-191055T","-191056G","-191057G","-191058A","-191059G","-191060T","-191061C","-191062G","-191063G","-191064T","-191065A","-191066G","-191067A","-191068T","-191069T","-191070T","-191071C","-191072A","-191073T","-191074G","-191075G","-191076C","-191077T","-191078G","-191079T","-191080C","-191081G","-191082A","-191083T","-191084G","-191085A","-191086G","-191087C","-191088A","-191089G","-191090T","-191091T","-191092T","-191093C","-191094A","-191095C","-191096G","-191097A","-191098C","-191099G","-191100A","-191101C","-191102C","-191103T","-191104C","-191105G","-191106A","-191107T","-191108C","-191109T","-191110T","-191111T","-191112G","-191113G","-191114T","-191115C","-191116A","-191117T","-191118T","-191119A","-191120T","-191121C","-191122T","-191123T","-191124T","-191125G","-191126G","-191127T","-191128A","-191129G"],"OPG037":["S185F"],"OPG180":["N59D"]},"labels":{"aa":"OPG037: S185F; OPG180: N59D"}}},{"name":"NODE_0000301","node_attrs":{"div":14,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C142797T"],"OPG164":["S7L"]},"labels":{"aa":"OPG164: S7L"}},"children":[{"name":"OR381841","node_attrs":{"div":14,"accession":"OR381841","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0645/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381841/2023-07-07"},"date":{"value":"2023-07-07"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OR326996","node_attrs":{"div":14,"accession":"OR326996","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0632/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR326996/2023-06-25"},"date":{"value":"2023-06-25"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T591A","-607T","-608T","-609T","A196619T"]}}},{"name":"OR326992","node_attrs":{"div":14,"accession":"OR326992","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0628/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR326992/2023-06-16"},"date":{"value":"2023-06-16"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","-179183T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-"]}}},{"name":"OR326991","node_attrs":{"div":15,"accession":"OR326991","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0627/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR326991/2023-06-15"},"date":{"value":"2023-06-15"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-","G165862T"]}}},{"name":"OR519724","node_attrs":{"div":14,"accession":"OR519724","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1022"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR519724/2023-08-XX"},"date":{"value":"2023-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-"]}}},{"name":"OR487998","node_attrs":{"div":15,"accession":"OR487998","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0680/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487998/2023-08-08"},"date":{"value":"2023-08-08"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["A176268G"],"OPG205":["S205G"]},"labels":{"aa":"OPG205: S205G"}}},{"name":"OR487990","node_attrs":{"div":14,"accession":"OR487990","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0669/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487990/2023-08-01"},"date":{"value":"2023-08-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OR487991","node_attrs":{"div":15,"accession":"OR487991","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0671/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487991/2023-08-02"},"date":{"value":"2023-08-02"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C165219T"],"OPG190":["S33F"]},"labels":{"aa":"OPG190: S33F"}}},{"name":"OR487989","node_attrs":{"div":15,"accession":"OR487989","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0668/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487989/2023-08-01"},"date":{"value":"2023-08-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G90093A"]}}},{"name":"OR487986","node_attrs":{"div":15,"accession":"OR487986","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0665/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487986/2023-08-01"},"date":{"value":"2023-08-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C72039T"]}}},{"name":"NODE_0000302_NODE_0000303_merged","node_attrs":{"div":16,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["T57476C"],"OPG075":["Q8R"]},"labels":{"aa":"OPG075: Q8R"}},"children":[{"name":"OR487995","node_attrs":{"div":17,"accession":"OR487995","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0675/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487995/2023-08-03"},"date":{"value":"2023-08-03"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C175864T"],"OPG205":["S70L"]},"labels":{"aa":"OPG205: S70L"}}},{"name":"OR487996","node_attrs":{"div":16,"accession":"OR487996","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0677/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487996/2023-08-07"},"date":{"value":"2023-08-07"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000303","node_attrs":{"div":16,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G173397A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-"]}},"children":[{"name":"OR743499","node_attrs":{"div":16,"accession":"OR743499","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1030"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR743499/2023-10-XX"},"date":{"value":"2023-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OR743500","node_attrs":{"div":16,"accession":"OR743500","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1031"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR743500/2023-10-XX"},"date":{"value":"2023-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{}}},{"name":"OR487992","node_attrs":{"div":16,"accession":"OR487992","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0672/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487992/2023-08-02"},"date":{"value":"2023-08-02"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-179244T","-179245C","-179246G","-179247T","-179248T","-179249A","-179250T","-179251T","-179252G","-179253T","-179254T","-179255T","-179256G","-179257G","-179258T","-179259C","-179260T","-179261A","-179262T","-179263G"]}}}]}]}]},{"name":"NODE_0000304","node_attrs":{"div":14,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G13563A"],"OPG025":["P569S"]},"labels":{"aa":"OPG025: P569S"}},"children":[{"name":"OR381843","node_attrs":{"div":14,"accession":"OR381843","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0649/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381843/2023-07-10"},"date":{"value":"2023-07-10"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OR381837","node_attrs":{"div":16,"accession":"OR381837","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0640/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381837/2023-06-27"},"date":{"value":"2023-06-27"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C29342T","C148438T","G150556A"],"OPG046":["E130K"],"OPG174":["E320K"]},"labels":{"aa":"OPG046: E130K; OPG174: E320K"}}},{"name":"OR381835","node_attrs":{"div":14,"accession":"OR381835","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0638/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381835/2023-06-27"},"date":{"value":"2023-06-27"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OR381834","node_attrs":{"div":15,"accession":"OR381834","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0636/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381834/2023-06-29"},"date":{"value":"2023-06-29"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G55497A"]}}},{"name":"OR381833","node_attrs":{"div":15,"accession":"OR381833","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0634/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381833/2023-07-03"},"date":{"value":"2023-07-03"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C176877T","-179186T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-"],"OPG205":["H408Y"]},"labels":{"aa":"OPG205: H408Y"}}},{"name":"OR326994","node_attrs":{"div":14,"accession":"OR326994","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0630/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR326994/2023-06-22"},"date":{"value":"2023-06-22"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-608T","G610-","T611-","-179186T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-"]}}},{"name":"OR326993","node_attrs":{"div":14,"accession":"OR326993","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0629/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR326993/2023-06-20"},"date":{"value":"2023-06-20"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["A150586-","T150587-","A150588-","T150589-","G150590-","A150591-","T150592-","G150593-","G150594-","A150595-","T150596-","A150597-","T150598-","G150599-","A150600-","T150601-","G150602-"]}}},{"name":"OR488000","node_attrs":{"div":17,"accession":"OR488000","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0682/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR488000/2023-08-07"},"date":{"value":"2023-08-07"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G49821A","G87187A","C190352T"],"OPG068":["E541K"],"OPG109":["S754L"]},"labels":{"aa":"OPG068: E541K; OPG109: S754L"}}},{"name":"OR487982","node_attrs":{"div":14,"accession":"OR487982","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0660/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487982/2023-07-26"},"date":{"value":"2023-07-26"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-607T"]}}},{"name":"OR487981","node_attrs":{"div":14,"accession":"OR487981","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0657/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487981/2023-07-21"},"date":{"value":"2023-07-21"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"NODE_0000305","node_attrs":{"div":15,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C117631T"],"OPG136":["D653N"]},"labels":{"aa":"OPG136: D653N"}},"children":[{"name":"OR381840","node_attrs":{"div":15,"accession":"OR381840","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0644/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381840/2023-07-07"},"date":{"value":"2023-07-07"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OR381839","node_attrs":{"div":15,"accession":"OR381839","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0643/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381839/2023-07-04"},"date":{"value":"2023-07-04"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000306","node_attrs":{"div":16,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C121394T","G162280A"],"OPG188":["E229K"]},"labels":{"aa":"OPG188: E229K"}},"children":[{"name":"OR743496","node_attrs":{"div":16,"accession":"OR743496","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1027"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR743496/2023-10-XX"},"date":{"value":"2023-10-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OR487994","node_attrs":{"div":16,"accession":"OR487994","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0674/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487994/2023-08-03"},"date":{"value":"2023-08-03"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OR487993","node_attrs":{"div":16,"accession":"OR487993","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0673/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487993/2023-08-03"},"date":{"value":"2023-08-03"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}}]},{"name":"NODE_0000307","node_attrs":{"div":15,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C37738T"],"OPG056":["E433K"]},"labels":{"aa":"OPG056: E433K"}},"children":[{"name":"OR487984","node_attrs":{"div":16,"accession":"OR487984","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0663/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487984/2023-07-28"},"date":{"value":"2023-07-28"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C15258T"],"OPG025":["D4N"]},"labels":{"aa":"OPG025: D4N"}}},{"name":"NODE_0000308","node_attrs":{"div":16,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G151847A"]}},"children":[{"name":"OR381844","node_attrs":{"div":18,"accession":"OR381844","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0650/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381844/2023-07-18"},"date":{"value":"2023-07-18"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-609T","G610-","T611-","G138584A","G151875A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-","G179268-","G179269-","A179270-","T179271-","A179272-","T179273-","C179274-","T179275-","T179276-","T179277-","A179278-","A179279-","A179280-"],"OPG156":["R276W"],"OPG178":["D123N"]},"labels":{"aa":"OPG156: R276W; OPG178: D123N"}}},{"name":"OR381836","node_attrs":{"div":16,"accession":"OR381836","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0639/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381836/2023-06-27"},"date":{"value":"2023-06-27"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OR381838","node_attrs":{"div":17,"accession":"OR381838","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"Monkeypox/PT0641/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR381838/2023-07-04"},"date":{"value":"2023-07-04"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-607T","-609T","G610-","T611-","C82619T"]}}},{"name":"OR326997","node_attrs":{"div":16,"accession":"OR326997","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0633/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR326997/2023-06-25"},"date":{"value":"2023-06-25"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["-608T","G610-","T611-","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-"]}}},{"name":"OR326995","node_attrs":{"div":17,"accession":"OR326995","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0631/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR326995/2023-06-22"},"date":{"value":"2023-06-22"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["G695-","T696-","C34435T","A196625-","T196626-"],"OPG053":["A86T"]},"labels":{"aa":"OPG053: A86T"}}},{"name":"OR487997","node_attrs":{"div":16,"accession":"OR487997","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0679/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487997/2023-08-08"},"date":{"value":"2023-08-08"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{}}},{"name":"OR487985","node_attrs":{"div":21,"accession":"OR487985","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0664/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487985/2023-08-01"},"date":{"value":"2023-08-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["C62243T","A132145G","G150054A","C162248T","G164445A"],"OPG081":["V15I"],"OPG176":["M82I"],"OPG188":["S218F"]},"labels":{"aa":"OPG081: V15I; OPG176: M82I; OPG188: S218F"}}},{"name":"OR487988","node_attrs":{"div":16,"accession":"OR487988","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0667/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487988/2023-08-01"},"date":{"value":"2023-08-01"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["A784-","T785-","T196689-","C196690-"]}}},{"name":"OR487980","node_attrs":{"div":16,"accession":"OR487980","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0656/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487980/2023-07-21"},"date":{"value":"2023-07-21"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T606-","A196614-"]}}},{"name":"OR487979","node_attrs":{"div":18,"accession":"OR487979","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0655/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487979/2023-07-21"},"date":{"value":"2023-07-21"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T12827C","C15258T"],"OPG023":["N25S"],"OPG025":["D4N"]},"labels":{"aa":"OPG023: N25S; OPG025: D4N"}}},{"name":"NODE_0000309","node_attrs":{"div":19,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["C56879T","C57492T","G121291A","T179244-","C179245-","G179246-","T179247-","T179248-","A179249-","T179250-","T179251-","G179252-","T179253-","T179254-","T179255-","G179256-","A196614-"],"OPG074":["E83K"],"OPG075":["E3K"]},"labels":{"aa":"OPG074: E83K; OPG075: E3K"}},"children":[{"name":"OR449307","node_attrs":{"div":21,"accession":"OR449307","author":{"author":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Pape,K.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1021"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR449307/2023-08-XX"},"date":{"value":"2023-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["C84191T","C115068T","A179169-","T179170-","A179171-","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"],"OPG133":["R210K"]},"labels":{"aa":"OPG133: R210K"}}},{"name":"OR487976","node_attrs":{"div":20,"accession":"OR487976","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0652/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487976/2023-07-19"},"date":{"value":"2023-07-19"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T606-","-179244T","-179245C","-179246G","-179247T","-179248T","-179249A","-179250T","-179251T","-179252G","-179253T","-179254T","-179255T","-179256G","C181495T"],"OPG210":["S47L"]},"labels":{"aa":"OPG210: S47L"}}},{"name":"OR487978","node_attrs":{"div":21,"accession":"OR487978","author":{"author":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P.","value":"Isidro,J.,Borges,V.,Pinto,M.,Sobral,D.,Santos,J.,Nunes,A.,Mixao,V.,Ferreira,R.,Santos,D.,Duarte,S.,Vieira,L.,Borrego,M.J.,Nuncio,S.,Lopes de Carvalho,I.,Pelerito,A.,Cordeiro,R.,Gomes,J.P."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/PT0654/2023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"National Institute of Health Doutor Ricardo Jorge, Portugal (INSA), Department of Infectious Diseases"},"strain_display":{"value":"Portugal/OR487978/2023-07-21"},"date":{"value":"2023-07-21"},"country":{"value":"Portugal"}},"branch_attrs":{"mutations":{"nuc":["T606-","T12827C","T12833A"],"OPG023":["N25S"]},"labels":{"aa":"OPG023: N25S"}}},{"name":"NODE_0000310","node_attrs":{"div":20,"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"clade_membership":{"value":"IIb"}},"branch_attrs":{"mutations":{"nuc":["G172945A"]}},"children":[{"name":"OR743493","node_attrs":{"div":20,"accession":"OR743493","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1024"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR743493/2023-08-XX"},"date":{"value":"2023-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-179194A","-179195T","G179257-","T179258-","C179259-","T179260-","A179261-","T179262-","G179263-","C179264-","C179265-","A179266-","T179267-"]}}},{"name":"OR519723","node_attrs":{"div":20,"accession":"OR519723","author":{"author":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A.","value":"Brinkmann,A.,Kohl,C.,Schrick,L.,Michel,J.,Schaade,L.,Nitsche,A."},"lineage":{"value":"C.1"},"outbreak":{"value":"hMPXV-1"},"strain":{"value":"MPXV/Germany/2023/ON/RKI1023"},"clade_membership":{"value":"IIb"},"host":{"value":"Homo sapiens"},"region":{"value":"Europe"},"institution":{"value":"Robert Koch Institute, Centre for Biological Threats, Highly Pathogenic Viruses"},"strain_display":{"value":"Germany/OR519723/2023-08-XX"},"date":{"value":"2023-08-XX"},"country":{"value":"Germany"}},"branch_attrs":{"mutations":{"nuc":["-179244T","-179245C","-179246G","-179247T","-179248T","-179249A","-179250T","-179251T","-179252G","-179253T","-179254T","-179255T","-179256G"]}}}]}]}]}]}]}]}]}]}]}]}]}]}]}]}]}} \ No newline at end of file